FrancophonIA/ELRC3.0 huggingface dataset:
English: Use within 60 days after first opening.
Croatian: Upotrijebiti u roku od 60 dana od prvog otvaranja.
English: Tenofovir concentrations not measured, no effect is expected.
Croatian: Koncentracije tenofovira nisu mjerene, ne očekuje se ikakav učinak.
English: - if you have severe liver disease.
Croatian: - ako bolujete od teške bolesti jetre.
English: - if you have a history of liver disease, including chronic active hepatitis.
Croatian: - ako ste nekada imali bolest jetre, uključujući kronični aktivni hepatitis.
English: Lopinavir concentrations: ↓ 30
Croatian: Koncentracije lopinavira: ↓ 30
English: This medicine is available in plastic bottles containing a desiccant labelled ‘DO NOT EAT' and 30 tablets and in multipacks of 90 tablets comprising 3 bottles, each containing 30 tablets.
Croatian: Lijek je dostupan u plastičnim bocama sa sredstvom za sušenje s oznakom „NE GUTATI” i 30 tableta i u višestrukim pakiranjima s 90 tableta u 3 boce od kojih svaka sadrži po 30 tableta.
English: - if you have or have had kidney disease, or if tests have shown problems with your kidneys.
Croatian: - ako imate ili ste imali bolest bubrega ili su testovi ukazivali na probleme s bubrezima.
English: It is believed that these symptoms are due to improvement in the body's immune response, enabling the body to fight infections that may have been present with no obvious symptoms.
Croatian: Vjeruje se da je uzrok tih simptoma poboljšanje imunološkog odaziva tijela koje tijelu omogućava da se bori protiv infekcija koje su možda bile prisutne bez pojave očitih simptoma.
English: Contraindications of concomitant use
Croatian: Kontraindikacije za istodobno korištenje
English: Tell your doctor immediately if you are pregnant or intend to become pregnant.
Croatian: Bez odlaganja obavijestite liječnika ako ste trudni ili namjeravate zanijeti.
English: Possible serious side effects: tell your doctor immediately
Croatian: Moguće ozbiljne nuspojave: odmah obavijestite liječnika
English: Patients with rare hereditary problems of galactose intolerance, the total lactase deficiency or glucosegalactose malabsorption should not take this medicine.
Croatian: Bolesnici s rijetkim nasljednim problemima intolerancije galaktoze, potpunim nedostatkom laktaze ili malapsorpcijom glukoze-galaktoze ne smiju uzimati ovaj lijek.
English: Decreases in bone mineral density of the hip were significantly greater in this group until 96 weeks.
Croatian: Smanjenje mineralne gustoće kosti kuka bilo je značajno veće u toj skupini do 96. tjedna.
English: The methadone dose was increased by a mean of 22% to alleviate withdrawal symptoms.
Croatian: Doza metadona povećana je za prosječno 22 % da bi se ublažili simptomi apstinencijske krize.
English: It is important to tell your doctor or pharmacist if you are taking any of the following:
Croatian: Važno je da kažete liječniku ili ljekarniku ako uzimate bilo koji od sljedećih lijekova:
English: Mean percent change in AUC, Cmax, Cmin with 90% confidence intervals if available
Croatian: Srednja vrijednost postotka promjene AUC, Cmax, Cmin uz 90 %-tne intervale pouzdanosti ako su dostupni
English: Your doctor will carefully consider whether to treat you with medicines containing tenofovir and didanosine.
Croatian: Liječnik će pažljivo razmotriti hoće li Vas liječiti lijekovima koji sadržavaju kombinaciju tenofovira i didanozina.
English: - any signs of skin rash.
Croatian: - bilo kakvi znakovi osipa na koži.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c (7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Croatian: Zahtjevi za podnošenje periodičkih izvješća o neškodljivosti za ovaj lijek definirani su u referentnom popisu datuma EU (EURD popis) predviđenom člankom 107.c stavkom 7. Direktive 2001/83/EZ i svim sljedećim ažuriranim verzijama objavljenima na europskom internetskom portalu za lijekove.
English: Do not use this medicine after the expiry date which is stated on the bottle and carton after ‘EXP'.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na boci i kutiji iza oznake „EXP”.
English: Similar results were found by other investigators, although the MPA plasma levels were more variable in the second study.
Croatian: Slične rezultate dobili su i drugi istraživači, iako su u drugom istraživanju postojale veće razlike u razinama MPA u plazmi.
English: - if you have a history of mental illness, including depression, or of substance or alcohol abuse.
Croatian: - ako ste nekada imali mentalnu bolest, uključujući depresiju, ili ovisnost o drogama ili alkoholu.
English: 117 Allée Des Parcs, 69 800 Saint-Priest, France
Croatian: 117 Allée Des Parcs, 69 800 Saint-Priest, Francuska
English: - Lactic acidosis (excess lactic acid in the blood) is a rare (may affect up to 1 in every 1,000 patients) but serious side effect that can be fatal.
Croatian: - Laktacidoza (prekomjerna količina mliječne kiseline u krvi) je rijetka (može se pojaviti u do 1 na svakih 1000 bolesnika), ali ozbiljna nuspojava koja može biti smrtonosna.
English: Stayed on original treatment regimen (N=97) n/N (%)
Croatian: Ostali na prvotnom režimu liječenja (N = 97) n/N (%)
English: - dry mouth - incoherent speech - increased appetite - libido decreased - myalgia
Croatian: - suha usta - inkoherentan govor - povećani apetit - smanjeni libido - mialgija
English: If appropriate, resumption of anti-hepatitis B therapy may be warranted.
Croatian: Ako je to prikladno, može biti opravdano nastaviti terapiju za hepatitis B.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 05 September 2017
Croatian: Datum prvog odobrenja: 05 rujna 2017
English: If available, 90% confidence intervals are shown in parentheses.
Croatian: U zagradama su prikazani 90 %-tni intervali pouzdanosti, ako su dostupni.
English: If you think you may have lactic acidosis, contact your doctor immediately.
Croatian: Mislite li da možda imate laktacidozu, odmah se obratite liječniku.
English: • disturbances of coordination and balance
Croatian: • alergijske reakcije • poremećaji koordinacije i ravnoteže
English: Patients coinfected with HIV and HBV
Croatian: Bolesnici istovremeno inficirani HIV-om i HBV-om
English: EXP: Once opened use within 60 days.
Croatian: EXP: Nakon otvaranja iskoristiti u roku od 60 dana.
English: It contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium-free'.
Croatian: Sadržava manje od 1 mmol natrija (23 mg) po dozi, što znači da je u biti „bez natrija”.
English: Emtricitabine (n=45)
Croatian: emtricitabin (n = 45)
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant Summary of Product Characteristics for these medicinal products.
Croatian: U slučaju istovremene antivirusne terapije hepatitisa B ili C, molimo također pročitajte Sažetak opisa svojstava lijeka za te lijekove.
English: Expected: Voxilaprevir:↓
Croatian: Očekivano: voksilaprevir:↓
English: They include some common medicines and some herbal preparations (including St. John's wort) which can cause serious interactions.
Croatian: Među njima su neki uobičajeni lijekovi i neki biljni pripravci (uključujući gospinu travu) koji mogu uzrokovati ozbiljne interakcije.
English: The clinical outcome of this observed reduction of boceprevir trough concentrations has not been directly assessed.
Croatian: Klinički ishod ovog opaženog smanjenja najnižih koncentracija boceprevira nije izravno procijenjen.
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Croatian: Ako uočite bilo koje simptome infekcije ili druge simptome poput slabosti mišića, slabosti koja počinje u šakama i stopalima i pomiče se nagore prema trupu tijela, osjećaja lupanja srca, nevoljnog drhtanja ili hiperaktivnosti, obavijestite svog liječnika odmah kako biste potražili liječničku pomoć.
English: Do not store above 25°C.
Croatian: Čuvati na temperaturi do 25 °C.
English: If overdose occurs, the patient must be monitored for evidence of toxicity (see section 4.8), and standard supportive treatment applied as necessary.
Croatian: U slučaju predoziranja bolesnika mora biti pod nadzorom zbog znakova toksičnosti (vidjeti dio 4.8) te mu se, prema potrebi, mora pružiti standardno potporno liječenje.
English: In uninfected volunteers, multiple doses of 200 to 400 mg per day for 10 days resulted in a lower than predicted extent of accumulation (22 to 42% lower) and a shorter terminal half-life of 40 to 55 hours (single dose half-life 52 to 76 hours).
Croatian: U neinficiranih dobrovoljaca više doza od 200 do 400 mg po danu tijekom 10 dana rezultiralo je manjom akumulacijom lijeka od predviđenog (manja za 22 do 42 %) i kraćim poluvijekom od 40 do 55 sati (poluvijek jedne doze 52 do 76 sati).
English: The biotransformation of emtricitabine includes oxidation of the thiol moiety to form the 3'-sulphoxide diastereomers (approximately 9% of dose) and conjugation with glucuronic acid to form 2'-O-glucuronide (approximately 4% of dose).
Croatian: Biotransformacija emtricitabina uključuje oksidaciju tiolne skupine, pri čemu nastaju diastereomeri 3'-sulfoksida (približno 9 % doze) i konjugaciju s glukoronskom kiselinom, pri čemu nastaje 2'-O-glukoronid (približno 4 % doze).
English: Patients should be informed that if they do occur, these common symptoms are likely to improve with continued therapy and are not predictive of subsequent onset of any of the less frequent psychiatric symptoms.
Croatian: Bolesnicima treba objasniti da će, ukoliko se pojave, ti uobičajeni simptomi biti ublaženi tijekom trajanja terapije te da se na temelju njih ne može predvidjeti naknadna pojava bilo kakvih manje čestih psihijatrijskih simptoma.
English: Co-administration with drugs that are known to prolong the QTc interval (proarryhthmic).
Croatian: Istodobna primjena s lijekovima za koje je poznato da produljuju QTc interval (proaritmici).
English: Modified LOCF: Post-hoc analysis where patients who failed virologically or discontinued for adverse events were treated as failures; for other drop-outs, the LOCF (last observation carried forward) method was applied
Croatian: Prilagođeni LOCF: Post-hoc analiza u kojoj su bolesnici u kojih je došlo do virološkog neuspjeha ili su prestali s liječenjem zbog nuspojava tretirani kao neuspješni; na ostale isključene bolesnike primijenjena je metoda LOCF (last observation carried forward)
English: Pharmacotherapeutic group: Antiviral for systemic use, antivirals for treatment of HIV infections, combinations, ATC code: J05AR06.
Croatian: Farmakoterapijska skupina: Antivirusni lijek za sistemsku primjenu, antivirusni lijekovi za liječenje infekcije HIV-om, kombinacije, ATK oznaka: J05AR06.
English: Rare completed suicide3,4, delusion3,4, neurosis3,4
Croatian: Rijetko izvršeno samoubojstvo3,4, deluzija3,4, neuroza3,4
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Croatian: Ako Vam je liječnik rekao da ne podnosite neke vrste šećera, obratite se liječniku prije uzimanja ovog lijeka.
English: In vitro binding of emtricitabine to human plasma proteins is < 4% and independent of concentrations over the range of 0.02 to 200 µg/ml.
Croatian: In vitro vezivanje emtricitabina na proteine ljudske plazme je < 4 % i neovisno je o koncentracijama u rasponu od 0,02 do 200 µg/ml.
English: Table 6: Summary of pharmacokinetic data from study GS-US-177-0105
Croatian: Tablica 6: Sažetak farmakokinetičkih podataka iz istraživanja GS-US-177-0105 efavirenz (n = 45)
English: Skin and subcutaneous tissue disorders: Very common rash (moderate-severe, 11.6%, all grades, 18%)3
Croatian: Poremećaji kože i potkožnog tkiva: Vrlo često osip (umjeren do težak, 11,6 %, svi stupnjevi, 18 %)3
English: Some patients taking combination antiretroviral therapy may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Croatian: U nekih se bolesnika koji uzimaju kombiniranu antiretrovirusnu terapiju može razviti koštana bolest koja se naziva osteonekrozom (odumiranje koštanog tkiva uzrokovano gubitkom dovoda krvi u kost).
English: Stevens-Johnson syndrome, erythema multiforme3, severe rash angioedema4
Croatian: Stevens-Johnsonov sindrom, multiformni eritem3, težak osip angioedem4
English: - Hormonal contraceptive, such as birth control pills, an injected contraceptive (for example, Depo-Provera), or a contraceptive implant (for example, Implanon): You must also use a reliable barrier method of contraception (see Pregnancy and breast-feeding).
Croatian: - Hormonalni kontraceptivi, kao što su pilule protiv začeća, kontraceptivi koji se primjenjuju injiciranjem (na primjer, Depo-Provera), ili kontraceptivni implantati (na primjer, Implanon): Morate koristiti i pouzdanu metodu barijerne kontracepcije (pogledajte Trudnoća i dojenje).
English: 6.6 Special precautions for disposal and other handling Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom Neiskorišteni lijek ili otpadni materijal potrebno je zbrinuti sukladno nacionalnim propisima.
English: - if you have a heart condition, such as an abnormal electrical signal called prolongation of the QT interval that puts you at high risk for severe heart rhythm problems (Torsade de Pointes).
Croatian: - ako imate bolest srca, kao što je abnormalan električni signal koji se naziva produljenje QT intervala, zbog čega ste izloženi visokom riziku od teških problema sa srčanim ritmom (torsade de pointes)
English: When efavirenz is co-administered with a calcium channel blocker that is a substrate of the CYP3A4 enzyme, there is a potential for reduction in the plasma concentrations of the calcium channel blocker.
Croatian: Ako se efavirenz primjenjuje istovremeno s blokatorom kalcijevih kanala koji je supstrat enzima CYP3A4, postoji mogućnost smanjenja plazmatske koncentracije blokatora kalcijevih kanala.
English: Immune system disorders: Common allergic reaction
Croatian: Poremećaji imunološkog sustava: Često alergijska reakcija
English: [To appear on outer carton only]
Croatian: [samo na vanjskom pakiranju]
English: The inducing effect of St. John's wort may persist for at least 2 weeks after cessation of treatment (see section 4.3).
Croatian: Indukcijski učinak gospine trave može potrajati najmanje 2 tjedna nakon prestanka njezinog uzimanja (vidjeti dio 4.3).
English: PVR (KM): Pure virologic response assessed using the Kaplan Meier (KM) method M: Missing
Croatian: PVR (KM): čisti virološki odgovor (Pure virologic response), ocijenjen primjenom Kaplan-Meierove (KM) metode
English: See section 2.
Croatian: Pogledajte dio 2.
English: Carbamazepine plasma levels should be monitored periodically.
Croatian: Povremeno se trebaju kontrolirati razine karbamazepina u plazmi.
English: PHARMACEUTICAL FORM AND CONTENTS 30 film-coated tablets
Croatian: OBLIK I SADRŽAJ 30 filmom obloženih tableta
English: In the open-label extended phase of study GS-01-934, where patients received efavirenz/emtricitabine/tenofovir disoproxil on an empty stomach, 3 additional cases of resistance were seen.
Croatian: U otvorenoj proširenoj fazi ispitivanja GS-01-934, u kojem su bolesnici uzimali efavirenz/emtricitabin/tenofovirdizoproksil na prazan želudac, opažena su 3 dodatna slučaja rezistencije.
English: Patients should be advised that if they experience symptoms such as severe depression, psychosis or suicidal ideation, they should contact their doctor immediately to assess the possibility that the symptoms may be related to the use of efavirenz, and if so, to determine whether the risk of continued therapy outweighs the benefits (see section 4.8).
Croatian: Bolesnike treba uputiti da se, osjete li simptome poput teške depresije, psihoze ili samoubilačkih ideja, moraju odmah obratiti svojem liječniku radi procjene moguće povezanosti tih simptoma s upotrebom efavirenza te, ako ta povezanost postoji, radi utvrđivanja nadmašuje li rizik uslijed nastavka terapije koristi od terapije (vidjeti dio 4.8).
English: Studies in humans and in vitro studies using human liver microsomes have demonstrated that efavirenz is principally metabolised by the CYP system to hydroxylated metabolites with subsequent glucuronidation of these hydroxylated metabolites.
Croatian: Ispitivanja na ljudima i in vitro ispitivanja uz korištenje ljudskih jetrenih mikrosoma pokazala su da se efavirenz pretežno metabolizira CYP sustavom, i to u hidroksilirane metabolite s naknadnom glukoronizacijom tih hidroksiliranih metabolita.
English: - Bupropion, a medicine used to treat depression or to help you stop smoking, as your doctor may need to change your dose of bupropion.
Croatian: - Bupropion, lijek koji se koristi za liječenje depresije ili kao pomoć za prestanak pušenja: liječnik će možda morati promijeniti dozu bupropiona.
English: No effect (↔) equals a decrease in mean ratio estimate of ≤ 20% or increase in mean ratio estimate of ≤ 25%.
Croatian: Bez učinka (↔) odgovara smanjenju procijenjenog omjera srednjih vrijednosti za ≤ 20 % ili povećanju procijenjenog omjera srednjih vrijednosti za ≤ 25 %.
English: The following side effects may be signs of lactic acidosis: - deep rapid breathing - drowsiness - feeling sick (nausea), being sick (vomiting) and stomach pain.
Croatian: Sljedeće nuspojave mogu biti znakovi laktacidoze: - duboko, brzo disanje - omamljenost - mučnina, povraćanje i bol u želucu.
English: Common cerebellar coordination and balance disturbances3, somnolence (2.0%)3, headache (5.7%)3, disturbance in attention (3.6%)3, dizziness dizziness headache
Croatian: Često cerebelarni poremećaji koordinacije i ravnoteže3, somnolencija (2,0 %)3, glavobolja (5,7 %)3, poremećaj pozornosti (3,6 %)3, omaglica (8,5%)3
English: These patients should be carefully monitored for efavirenz adverse reactions, especially nervous system symptoms.
Croatian: Te bolesnike nužno je pomno pratiti radi pojave nuspojava efavirenza, naročito simptoma na živčanom sustavu.
English: - Ginkgo biloba extracts (herbal preparation).
Croatian: - Ekstrakt Ginkgo biloba (biljni pripravak).
English: 2 Thymidine analogue associated mutations included D67N (n=1) and K70R (n=1).
Croatian: 2 Mutacije povezane s analogom timidina uključivale su D67N (n = 1) i K70R (n = 1).
English: Patients either changed to efavirenz/emtricitabine/tenofovir disoproxil (N=203) or continued on their original antiretroviral treatment regimen (N=97).
Croatian: Bolesnici su ili prešli na efavirenz/emtricitabin/tenofovirdizoproksil (N = 203) ili su nastavili sa svojim prvotnim režimom antiretrovirusnog liječenja (N = 97).
English: United Kingdom Generics [UK] Ltd Tel: +44 1707 853000
Croatian: Ujedinjeno Kraljevstvo Generics [UK] Ltd Tel: +44 1707 853000
English: McDermott Laboratories Limited t/a Gerard Laboratories t/a Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited t/a Gerard Laboratories t/a Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Irska
English: SPECIAL STORAGE CONDITIONS Do not store above 25°C.
Croatian: POSEBNE MJERE ČUVANJA Čuvati na temperaturi do 25 °C.
English: Patients with pre-existing liver dysfunction including chronic active hepatitis have an increased frequency of liver function abnormalities during combination antiretroviral therapy (CART) and should be monitored according to standard practice.
Croatian: Bolesnici s otprije postojećim poremećajem funkcije jetre, uključujući kronični aktivni hepatitis, imaju povećanu učestalost abnormalnosti funkcije jetre tijekom kombinirane antiretrovirusne terapije (combination antiretroviral therapy, CART), pa ih treba nadzirati u skladu sa standardnom praksom.
English: - signs of dizziness, difficulty sleeping, drowsiness, difficulty concentrating or abnormal dreaming.
Croatian: - pojava omaglice, otežanog spavanja, omamljenosti, problema u koncentraciji ili nenormalnih snova.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING INNER CARTON OF BOTTLE MULTIPACK (WITHOUT BLUE BOX)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU UNUTRAŠNJA KUTIJA VIŠESTRUKOG PAKIRANJA BOCE (BEZ PLAVOG OKVIRA)
English: Cmin: ↓ 8% (↑ 14 to ↓ 25) Norelgestromin (active metabolite):
Croatian: Cmin: ↓ 8 % (↑ 14 do ↓ 25) norelgestromin (aktivni metabolit):
English: It is recommended that creatinine clearance is calculated in all patients prior to initiating therapy with efavirenz/emtricitabine/tenofovir disoproxil and renal function (creatinine clearance and serum phosphate) is also monitored after two to four weeks of treatment, after three months of treatment and every three to six months thereafter in patients without renal risk factors.
Croatian: Preporučuje se izračunati klirens kreatinina u svih bolesnika prije nego se započne terapija efavirenzom/emtricitabinom/tenofovirdizoproksilom te pratiti funkciju bubrega (klirens kreatinina i razinu fosfata u serumu) nakon dva do četiri tjedna liječenja, nakon tri mjeseca liječenja i svakih tri do šest mjeseci nakon toga u bolesnika bez bubrežnih čimbenika rizika.
English: In vitro binding of tenofovir to human plasma or serum protein is < 0.7% and 7.2%, respectively over the tenofovir concentration range 0.01 to 25 µg/ml.
Croatian: In vitro vezivanje tenofovira na proteine ljudske plazme ili seruma je < 0,7 %, odnosno 7,2 %, u rasponu koncentracija tenofovira od 0,01 do 25 µg/ml.
English: McDermott Laboratories Limited t/a Gerard Laboratories t/a Mylan Dublin 35/36 Baldoyle Industrial Estate, Baldoyle, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited t/a Gerard Laboratories t/a Mylan Dublin 35/36 Baldoyle Industrial Estate, Baldoyle, Dublin 13 Irska
English: Laboratory tests should be performed to evaluate their liver disease at periodic intervals (see section 4.2).
Croatian: Nužno je periodički vršiti laboratorijske testove kako bi se procijenila njihova bolest jetre (vidjeti dio 4.2).
English: - Sertraline, a medicine used to treat depression, as your doctor may need to change your dose of sertraline.
Croatian: - Sertralin, lijek koji se koristi za liječenje depresije; liječnik će možda morati promijeniti dozu sertralina.
English: Film-coated tablet.
Croatian: Filmom obložena tableta
English: In HIV infected patients, peak efavirenz plasma concentrations were attained by 5 hours and steadystate concentrations reached in 6 to 7 days.
Croatian: U bolesnika inficiranih HIV-om najviše koncentracije efavirenza u plazmi postignute su za 5 sati, a koncentracija u stanju dinamičke ravnoteže za 6 do 7 dana.
English: Cmax: ↓ 19% (↓ 40 to ↑ 10) GS-3310071:
Croatian: Cmax: ↓ 19 % (↓ 40 do ↑ 10) GS-3310071:
English: Compounds or herbal preparations (for example Ginkgo biloba extracts and St. John's wort) which induce these enzymes may give rise to decreased plasma concentrations of efavirenz.
Croatian: Spojevi ili biljni preparati (na primjer, ekstrakt Ginkgo biloba i gospina trava), koji induciraju ove enzime, mogu dovesti do smanjenja koncentracije efavirenza u plazmi.
English: Patients who are receiving concomitant anticonvulsant medicinal products primarily metabolised by the liver, such as phenytoin, carbamazepine and phenobarbital, may require periodic monitoring of plasma levels.
Croatian: U bolesnika koji istovremeno primaju antikonvulzivne lijekove koji se primarno metaboliziraju u jetri, poput fenitoina, karbamazepina i fenobarbitala, može postojati potreba za povremenom kontrolom razine ovih lijekova u plazmi.
English: If you are over 65 years of age and are prescribed Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan, your doctor will monitor you carefully.
Croatian: Ako ste stariji od 65 godina, a propisan Vam je Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, liječnik će Vas pažljivo nadzirati.