FrancophonIA/ELRC3.0 huggingface dataset:
English: VANTAVO must be taken with water only (not mineral water) at least 30 minutes before the first food, beverage, or medicinal product (including antacids, calcium supplements and vitamins) of the day.
Slovenian: Zdravilo VANTAVO je treba vzeti izključno z navadno vodo (ne z mineralno vodo) najmanj 30 minut pred prvim dnevnim obrokom hrane in pijače ali zaužitjem drugih zdravil (vključno z antacidi, pripravki kalcija in vitamini).
English: • allergic reactions such as hives; swelling of the face, lips, tongue and/or throat, possibly causing difficulty breathing or swallowing; severe skin reactions.
Slovenian: • alergijske reakcije, kot so koprivnica, otekanje obraza, ustnic, jezika in/ali žrela, ki lahko otežuje dihanje ali požiranje, hude kožne reakcije
English: There were no differences in mean serum calcium, phosphate, or 24-hour urine calcium between treatment groups.
Slovenian: Med skupinama ni bilo razlik v povprečni vrednosti serumskega kalcija, serumskega fosfata ali kalcija v 24-urnem urinu.
English: Results are insufficient to support the use of alendronate sodium in paediatric patients with osteogenesis imperfecta.
Slovenian: Rezultati, ki bi podprli uporabo natrijevega alendronata pri pediatričnih bolnikih z imperfektno osteogenezo, so pomanjkljivi.
English: Lesser amounts are distributed to adipose and muscle tissue and stored as vitamin D3 at these sites for later release into the circulation.
Slovenian: Manjše količine se porazdelijo v maščevje in mišičje, kjer se kot vitamin D3 uskladiščijo za poznejše sproščanje v obtok.
English: VANTAVO should not be used during pregnancy.
Slovenian: Zdravila VANTAVO se med nosečnostjo ne sme uporabljati.
English: In the absence of adequate sunlight exposure, vitamin D3 is an essential dietary nutrient.
Slovenian: V primeru nezadostne izpostavljenosti soncu, je vitamin D3 treba vnesti s hrano.
English: • your doctor has told you that you have Barrett's oesophagus (a condition associated with changes in the cells that line the lower oesophagus),
Slovenian: • če vam je zdravnik povedal, da imate Barrettov požiralnik (stanje, povezano s spremembami sluznice v spodnjem delu požiralnika),
English: When you get out of bed on the day you have chosen, and before taking your first food, drink or other medicines, swallow (do not crush or chew the tablet or allow it to dissolve in your mouth) one VANTAVO tablet with a full glass of water (not mineral water).
Slovenian: Ko na izbrani dan zjutraj vstanete in še preden pojeste prvo hrano ali popijete prvo pijačo ali vzamete katero koli drugo zdravilo, pogoltnite (ne zdrobite, ne žvečite in ne raztapljajte v ustih) eno tableto VANTAVO s polnim kozarcem vode (ne z mineralno vodo).
English: Severe vitamin D deficiency may cause muscle weakness which can lead to falls and a greater risk of fractures.
Slovenian: Hudo pomanjkanje vitamina D lahko povzroči mišično oslabelost, zaradi česar se poveča verjetnost padcev in tveganje za zlome.
English: It is likely that calcium supplements, antacids, and some oral medicines will interfere with the absorption of VANTAVO if taken at the same time.
Slovenian: Dodatki kalcija, antacidi in nekatera zdravila, ki jih zaužijete, lahko motijo absorpcijo zdravila VANTAVO, če jih vzamete istočasno.
English: Since Non Steroidal Anti-Inflammatory Drug (NSAID) use is associated with gastrointestinal irritation, caution should be used during concomitant use with alendronate.
Slovenian: Ker so nesteroidna protivnetna zdravila (NSAR-i) povezana z draženjem prebavil, moramo biti pri sočasni uporabi z alendronatom previdni.
English: In clinical studies, asymptomatic, mild and transient decreases in serum calcium and phosphate were observed in approximately 18 % and 10 %, respectively, of patients taking alendronate 10 mg/day versus approximately 12 % and 3 % of those taking placebo.
Slovenian: V kliničnih študijah so opazili asimptomatska, blaga in prehodna znižanja serumskega kalcija in fosfata: pri bolnikih, ki so jemali alendronat 10 mg/dan, za približno 18 % oz. 10 %, pri bolnikih, ki so jemali placebo, pa za približno 12 % oz. 3 %.
English: Uncommon eye inflammation (uveitis, scleritis, or episcleritis)
Slovenian: Občasni vnetje oči (uveitis, skleritis ali episkleritis)
English: This adverse reaction was identified through post-marketing surveillance.
Slovenian: Ta neželeni učinek so opažali v obdobju trženja.
English: Insufficiency is associated with negative calcium balance, bone loss, and increased risk of skeletal fracture.
Slovenian: Pri pomanjkanju pride do negativne bilance kalcija, izgube kostnine in povečanja tveganja za zlome kosti.
English: 6) After swallowing your VANTAVO tablet, wait at least 30 minutes before taking your first food, drink, or other medicine of the day, including antacids, calcium supplements and vitamins.
Slovenian: 6) Ko pogoltnete tableto VANTAVO, vsaj še 30 minut počakajte, preden zaužijete prvo hrano, pijačo ali katero koli drugo zdravilo, vključno z antacidi, dodatki kalcija in vitamini.
English: How to take VANTAVO tablets
Slovenian: Kako jemati tablete VANTAVO
English: What you need to know before you take VANTAVO
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo VANTAVO
English: Patients should be instructed that if they miss a dose of VANTAVO they should take one tablet on the morning after they remember.
Slovenian: Bolnikom je treba naročiti, naj v primeru, da pozabijo vzeti odmerek zdravila VANTAVO, vzamejo eno tableto zjutraj potem, ko se spomnijo.
English: During bisphosphonate treatment, all patients should be encouraged to maintain good oral hygiene, receive routine dental check-ups, and report any oral symptoms such as dental mobility, pain, or swelling.
Slovenian: Med zdravljenjem z bisfosfonati je treba bolnike spodbujati, da vzdržujejo dobro ustno higieno, da redno hodijo na zobozdravniške preglede in da poročajo o kakršnih koli simptomih v ustih, kot so majavost zob, bolečina ali otekanje.
English: Vitamin D3 is produced in the skin by conversion of 7-dehydrocholesterol to vitamin D3 by ultraviolet light.
Slovenian: Vitamin D3 se tvori v koži s pretvorbo 7-dehidroholesterola v vitamin D3 z ultravijolično svetlobo.
English: • transient flu-like symptoms, such as aching muscles, generally feeling unwell and sometimes with fever usually at the start of treatment,
Slovenian: • prehodni gripi podobni simptomi, kot npr. bolečine v mišicah, splošno slabo počutje in včasih zvišana telesna temperatura, običajno ob začetku zdravljenja
English: 2031 BN, Haarlem, Netherlands
Slovenian: 2031 BN, Haarlem, Nizozemska
English: Additional supplementation with vitamin D should be considered on an individual basis taking into account any vitamin D intake from vitamins and dietary supplements.
Slovenian: O jemanju dodatkov vitamina D je treba presoditi pri vsakem bolniku posebej, pri tem pa upoštevati vnos vitamina D z vitamini in prehrano.
English: 4) Do not take VANTAVO at bedtime or before getting up for the day.
Slovenian: 4) Zdravila VANTAVO ne jemljite zvečer ali preden zjutraj vstanete.
English: In severe cases, deficiency results in secondary hyperparathyroidism, hypophosphataemia, proximal muscle weakness and osteomalacia, further increasing the risk of falls and fractures in osteoporotic individuals.
Slovenian: Pri hudem pomanjkanju se pojavi sekundarni hiperparatiroidizem, hipofosfatemija, oslabelost proksimalnih mišic in osteomalacija, kar še bolj poveča tveganje za padce in zlome pri bolnikih z osteoporozo.
English: Circulating vitamin D3 is bound to vitamin D-binding protein.
Slovenian: Vitamin D3 v obtoku je vezan na vitamin D-vezavno beljakovino.
English: The principal action of 1,25-dihydroxyvitamin D3 is to increase intestinal absorption of both calcium and phosphate as well as regulate serum calcium, renal calcium and phosphate excretion, bone formation and bone resorption.
Slovenian: Glavni učinek 1,25-dihidroksivitamina D3 je povečanje absorpcije kalcija in fosfata v črevesju, uravnava pa tudi količino kalcija v serumu, izločanje kalcija in fosfata skozi ledvice ter tvorbo in resorpcijo kosti.
English: PARTICULARS TO APPEAR WITHIN THE OUTER PACKAGING (CARTON)
Slovenian: PODATKI, KI MORAJO BITI NAVEDENI NA ZUNANJI OVOJNINI (ŠKATLA)
English: Bone and mineral metabolism Causes of osteoporosis other than oestrogen deficiency and ageing should be considered.
Slovenian: Presnova kosti in mineralov Poleg pomanjkanja estrogena in staranja je treba upoštevati tudi druge vzroke za osteoporozo.
English: What VANTAVO looks like and contents of the pack
Slovenian: Izgled zdravila VANTAVO in vsebina pakiranja
English: In healthy subjects, oral prednisone (20 mg three times daily for five days) did not produce a clinically meaningful change in oral bioavailability of alendronate (a mean increase ranging from 20 % to 44 %).
Slovenian: Pri zdravih preiskovancih peroralni prednizon (20 mg trikrat dnevno, pet dni) ni povzročil klinično pomembne spremembe v biološki uporabnosti po peroralni uporabi alendronata (povprečni porast od 20 % do 44 %).
English: Non-clinical studies with the combination of alendronate and colecalciferol have not been conducted.
Slovenian: Predklinične študije s kombinacijo alendronata in holekalciferola niso bile izvedene.
English: While no increased risk was observed in extensive clinical trials with alendronate, there have been rare (post-marketing) reports of gastric and duodenal ulcers, some of which were severe and with complications (see section 4.8).
Slovenian: Čeprav v obsežnih kliničnih preskušanjih z alendronatom povečanega tveganja niso opazili, so v obdobju trženja zdravila v redkih primerih poročali o razjedah v želodcu in dvanajstniku (nekatere so bile resne in s komplikacijami) (glejte poglavje 4.8).
English: • a history of dental disease, poor oral hygiene, periodontal disease, invasive dental procedures and poorly fitting dentures
Slovenian: • anamnezo bolezni zob, slabo ustno higieno, bolezen dlesni, invazivni zobozdravniški poseg in slabo prilegajočo zobno protezo.
English: Alendronate sodium is a bisphosphonate that inhibits osteoclastic bone resorption with no direct effect on bone formation.
Slovenian: Natrijev alendronat je bisfosfonat, ki zavira delovanje osteoklastov in s tem kostno resorpcijo, nima pa neposrednega vpliva na proces tvorbe kosti.
English: Take one tablet once a week.
Slovenian: Vzemite eno tableto enkrat na teden.
English: Patients may experience certain adverse reactions (for example, blurred vision, dizziness and severe bone muscle or joint pain (see section 4.8)) that may influence the ability to drive and use machines.
Slovenian: Pri bolnikih se lahko pojavijo določeni neželeni učinki (npr. zamegljen vid, omotica in hude bolečine v kosteh, mišicah ali sklepih (glejte poglavje 4.8)), ki lahko vplivajo na sposobnost vožnje in upravljanja strojev.
English: Vitamin D insufficiency develops when both sunlight exposure and dietary intake are inadequate.
Slovenian: Pomanjkanje vitamina D se pojavi, kadar sta premajhna tako izpostavljenost soncu, kot tudi vnos s hrano.
English: An Instruction Card is included in the carton for VANTAVO.
Slovenian: V škatli zdravila VANTAVO je priložena kartica z navodili.
English: It reduces the risk of vertebral and hip fractures.
Slovenian: Zmanjša tveganje za zlome hrbtenice in kolka.
English: At doses far higher than the human therapeutic range, reproductive toxicity has been observed in animal studies.
Slovenian: Pri odmerkih, ki daleč presegajo terapevtsko območje pri ljudeh, so v študijah na živalih opazili škodljiv vpliv na sposobnost razmnoževanja.
English: • potency of the bisphosphonate (highest for zoledronic acid), route of administration (see above)
Slovenian: • jakost bisfosfonatov (največja pri zoledronski kislini), pot uporabe (glejte zgoraj) in kumulativni odmerek,
English: • stomach or peptic ulcers (sometimes severe or with bleeding),
Slovenian: • razjede v želodcu ali dvanajstniku (včasih hude ali s krvavitvijo)
English: Osteonecrosis of the jaw has also been reported in patients with osteoporosis receiving oral bisphosphonates.
Slovenian: O osteonekrozi čeljusti so poročali tudi pri bolnikih z osteoporozo, ki so prejemali peroralne bisfosfonate.
English: - Abnormalities of the oesophagus and other factors which delay oesophageal emptying such as stricture or achalasia.
Slovenian: - Nenormalnosti požiralnika in drugi dejavniki, ki upočasnjujejo praznjenje požiralnika, kot sta zožitev ali ahalazija.
English: In this study, a significant difference was observed in the analysis of the subgroup of osteoporotic women (37 % of the global population who correspond with the above definition of osteoporosis) in the incidence of hip fractures (alendronate 1.0 % vs. placebo 2.2 %, a reduction of 56 %) and in the incidence of  1 vertebral fracture (2.9 % vs. 5.8 %, a reduction of 50 %).
Slovenian: V tej študiji so pri analizi podskupine žensk z osteoporozo (37 % svetovne populacije, ki ustreza že omenjeni definiciji osteoporoze) opazili pomembno razliko v pojavnosti zlomov kolka (alendronat 1,0 % v primerjavi s placebom 2,2 %, 56 % zmanjšanje) in v pojavnosti ≥ 1 zlomov vretenc (2,9 % v primerjavi s 5,8 %, 50 % zmanjšanje).
English: Bioavailability was decreased similarly to an estimated 0.46 % and 0.39 % when alendronate was administered one hour or half an hour before a standardised breakfast.
Slovenian: Biološka uporabnost se je pri zaužitju alendronata eno uro ali pol ure pred standardiziranim zajtrkom podobno zmanjšala na ocenjenih 0,46 % oz. 0,39 %.
English: The possibility of osteonecrosis of the external auditory canal should be considered in patients receiving bisphosphonates who present with ear symptoms such as pain or discharge, or chronic ear infections.
Slovenian: Možnost osteonekroze zunanjega slušnega kanala je treba upoštevati pri bolnikih, ki prejemajo bisfosfonate in pri katerih se pojavljajo simptomi bolezni ušesa, kot sta bolečina ali izcedek, ali kronična vnetja ušesa.
English: The therapeutic equivalence of alendronate once weekly 70 mg (n=519) and alendronate 10 mg daily (n=370) was demonstrated in a one-year multicentre study of post-menopausal women with osteoporosis.
Slovenian: Terapevtsko ekvivalenco alendronata 70 mg enkrat tedensko (n = 519) in alendronata 10 mg enkrat dnevno (n = 370) so dokazali v enoletni multicentrični študiji pri ženskah s pomenopavzalno osteoporozo.
English: Alendronate given during pregnancy in rats caused dystocia related to hypocalcaemia (see section 5.3).
Slovenian: Alendronat, ki so ga dajali brejim podganam, je povzročil distocijo, povezano s hipokalciemijo (glejte poglavje 5.3).
English: Medicines for fits (seizures) (like phenytoin or phenobarbital) may decrease the effectiveness of vitamin D. Additional vitamin D supplements may be considered on an individual basis.
Slovenian: Zdravila proti krčem (napadom) (kot sta fenitoin ali fenobarbital) lahko zmanjšajo učinek vitamina D. Pri posameznih bolnikih lahko pride v poštev jemanje dodatkov vitamina D.
English: VANTAVO is only intended for use in postmenopausal women.
Slovenian: Zdravilo VANTAVO je namenjeno le ženskam po menopavzi.
English: • Patients should only swallow VANTAVO whole.
Slovenian: • Bolnik mora pogoltniti celo tableto VANTAVO.
English: The mean steady-state volume of distribution, exclusive of bone, is at least 28 litres in humans.
Slovenian: Povprečni volumen porazdelitve v stanju dinamičnega ravnovesja (brez kosti), je pri ljudeh vsaj 28 litrov.
English: It is very important that the full dosing instructions are provided to, and are understood by the patient (see section 4.2).
Slovenian: Zelo pomembno je, da se bolnika natančno pouči, kako naj jemlje alendronat, in da bolnik navodila tudi razume (glejte poglavje 4.2).
English: VANTAVO is effective only if taken when your stomach is empty.
Slovenian: Zdravilo VANTAVO je učinkovito samo, če ga vzamete na tešče.
English: A small percentage of vitamin D3 undergoes glucuronidation prior to elimination.
Slovenian: Pri majhnem deležu vitamina D3 pred izločanjem pride do glukuronidacije.
English: The following adverse reactions have been reported during clinical studies and/or post-marketing use with alendronate.
Slovenian: Seznam neželenih učinkov v preglednici Iz kliničnih študij in/ali v obdobju trženja alendronata so poročali o naslednjih neželenih učinkih.
English: • blurred vision; pain or redness in the eye,
Slovenian: • zamegljen vid, bolečina v očesu ali rdeče oko
English: Olestra, mineral oils, orlistat, and bile acid sequestrants (e.g. cholestyramine, colestipol) may impair the absorption of vitamin D. Anticonvulsants, cimetidine and thiazides may increase the catabolism of vitamin D. Additional vitamin D supplements may be considered on an individual basis.
Slovenian: Olestra, mineralna olja, orlistat in izmenjevalci žolčnih kislin (npr. holestiramin, holestipol) lahko motijo absorpcijo vitamina D. Antikonvulzivi, cimetidin in tiazidi lahko povečajo razgradnjo vitamina D. Pri posameznih bolnikih lahko pride v poštev še dodatno jemanje vitamina D.
English: During bisphosphonate treatment patients should be advised to report any thigh, hip or groin pain and any patient presenting with such symptoms should be evaluated for an incomplete femur fracture.
Slovenian: Bolnikom je treba svetovati, naj v času zdravljenja z bisfosfonati sporočijo kakršne koli bolečine v stegnu, kolku ali dimljah, vsakega bolnika z navedenimi simptomi pa je treba pregledati glede nepopolnega zloma stegnenice.
English: Certain medicines for rheumatism or long-term pain called NSAIDs (e.g. acetylsalicylic acid or ibuprofen) might cause digestive problems.
Slovenian: Določena zdravila za zdravljenje revmatičnih obolenj ali dolgotrajne bolečine, imenovana nesteroidni antirevmatiki (NSAID) (npr: acetilsalicilna kislina ali ibuprofen), lahko povzročijo prebavne motnje.
English: Studies in animals have shown hypercalcaemia and reproductive toxicity with high doses of vitamin D (see section 5.3).
Slovenian: Študije na živalih so pri velikih odmerkih vitamina D pokazale hiperkalciemijo in vpliv na sposobnost razmnoževanja (glejte poglavje 5.3).
English: Therefore, somewhat greater accumulation of alendronate in bone might be expected in patients with impaired renal function (see section 4.2).
Slovenian: Zato se pri bolnikih z okvaro ledvične funkcije pričakuje nekoliko večje kopičenje alendronata v kosteh (glejte poglavje 4.2).
English: Irritation, inflammation or ulceration of the gullet (oesophagus - the tube that connects your mouth with your stomach) often with symptoms of chest pain, heartburn, or difficulty or pain upon swallowing may occur, especially if patients do not drink a full glass of water and/or if they lie down less than 30 minutes after taking VANTAVO.
Slovenian: Po zaužitju lahko pride do draženja, vnetja ali razjede požiralnika, pogosto z bolečino v prsnem košu, zgago ali oteženim ali bolečim požiranjem, še posebej, če bolnik ne spije polnega kozarca vode in/ali če se uleže prej kot v 30 minutah po zaužitju zdravila VANTAVO.
English: The mean half-life of vitamin D3 in the serum following an oral dose of VANTAVO (70 mg/2800 IU) is approximately 24 hours.
Slovenian: Povprečni razpolovni čas vitamina D3 v serumu po peroralnem odmerku zdravila VANTAVO (70 mg/2.800 i.e.) je približno 24 ur.
English: Studies in rats have shown that treatment with alendronate during pregnancy was associated with dystocia in dams during parturition which was related to hypocalcaemia.
Slovenian: Študije na podganah so pokazale, da je bila distocija med porodom zaradi hipokalciemije povezana z zdravljenjem z alendronatom.
English: Vitamin D toxicity has not been documented during chronic therapy in generally healthy adults at a dose less than 10,000 IU/day.
Slovenian: Toksičnega učinka vitamina D pri sicer na splošno zdravih odraslih, ki so dlje časa dobivali odmerke manj kot 10.000 i.e. dnevno, niso zabeležili.
English: • pain in the mouth, and/or jaw, swelling or sores inside the mouth, numbness or a feeling of heaviness in the jaw, or loosening of a tooth.
Slovenian: • bolečina v ustih in/ali čeljusti, otekanje ali ranice v ustih, odrevenelost ali občutek pritiska v čeljusti ali majanje zoba.
English: In the initial efficacy studies, the mean BMD increases with alendronate 10 mg/day relative to placebo at three years were 8.8 %, 5.9 % and 7.8 % at the spine, femoral neck and trochanter, respectively.
Slovenian: V začetnih študijah učinkovitosti se je povprečna MKG hrbtenice, vratu stegnenice oz. trohantra pri zdravljenju z alendronatom 10 mg/dan v primerjavi s placebom po treh letih zvišala za 8,8 %, 5,9 % oz. 7,8 %.
English: If you forget to take VANTAVO
Slovenian: Če ste pozabili vzeti zdravilo VANTAVO
English: A. MANUFACTURER (S) RESPONSIBLE FOR BATCH RELEASE
Slovenian: A. IZDELOVALEC (IZDELOVALCI), ODGOVOREN (ODGOVORNI) ZA SPROŠČANJE SERIJ
English: Alendronate can cause local irritation of the upper gastrointestinal mucosa.
Slovenian: Alendronat lahko povzroči lokalno draženje sluznice zgornjega dela prebavil.
English: It is likely that food and beverages (including mineral water) will make VANTAVO less effective if taken at the same time.
Slovenian: Hrana in pijače (vključno z mineralno vodo) lahko ob sočasnem zaužitju zmanjšajo učinek zdravila VANTAVO.
English: Musculoskeletal and connective tissue disorders
Slovenian: Bolezni mišičnoskeletnega sistema in vezivnega tkiva
English: The other ingredients are microcrystalline cellulose (E460), lactose anhydrous (see section 2), medium chain triglycerides, gelatin, croscarmellose sodium, sucrose (see section 2), colloidal silicon dioxide, magnesium stearate (E572), butyl hydroxytoluene (E321), modified starch (maize), and sodium aluminium silicate (E554).
Slovenian: Pomožne snovi so: mikrokristalna celuloza (E460), brezvodna laktoza (glejte poglavje 2), srednjeverižni trigliceridi, želatina, premreženi natrijev karmelozat, saharoza (glejte poglavje 2), koloidni silicijev dioksid, magnezijev stearat (E572), butilhidroksitoluen (E321), modificirani škrob (koruzni) in aluminijev natrijev silikat (E554).
English: This medicinal product contains lactose and sucrose.
Slovenian: To zdravilo vsebuje laktozo in saharozo.
English: Alendronate
Slovenian: Alendronat
English: • if you have certain problems with your gullet (oesophagus - the tube that connects your mouth with your stomach) such as narrowing or difficulty swallowing,
Slovenian: • če imate določene težave s požiralnikom (del prebavne cevi, ki povezuje usta in želodec), kot je njegovo zoženje ali oteženo požiranje,
English: Neopharmed Gentili S.p.A. Tel. + 39 02 89 13 21 regulatory@neogen.it
Slovenian: Tel. + 39 02 89 13 21 regulatory@neogen.it
English: If you stop taking VANTAVO
Slovenian: Če ste prenehali jemati zdravilo VANTAVO
English: 5 How to store VANTAVO Contents of the pack and other information
Slovenian: Shranjevanje zdravila VANTAVO Vsebina pakiranja in dodatne informacije
English: Vitamin D3 is rapidly metabolized by hydroxylation in the liver to 25-hydroxyvitamin D3, and subsequently metabolized in the kidney to 1,25-dihydroxyvitamin D3, which represents the biologically active form.
Slovenian: Vitamin D3 se v jetrih s hidroksilacijo hitro presnovi v 25-hidroksivitamin D3, nato pa se v ledvicah presnovi v 1,25-dihidroksivitamin D3, ki je biološko aktivna oblika.
English: • tiredness; swelling in the hands or legs.
Slovenian: • utrujenost, otekanje dlani ali nog
English: No specific information is available on the treatment of overdose with alendronate.
Slovenian: Posebnih napotkov o ukrepih pri prekomernem odmerjanju alendronata ni na voljo.
English: †, pruritus Uncommon rash, erythema Rare rash with photosensitivity, severe skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis
Slovenian: Redki izpuščaj z občutljivostjo na svetlobo, hude kožne reakcije, vključno s Stevens-Johnsonovim sindromom in toksično epidermalno nekrolizo
English: Return to taking one tablet once a week, as originally scheduled on your chosen day.
Slovenian: Nadaljevati morajo z jemanjem ene tablete enkrat na teden na izbrani dan, tako kot so prvotno načrtovali.
English: Activity of osteoclasts is inhibited, but recruitment or attachment of osteoclasts is not affected.
Slovenian: Zavrto je delovanje osteoklastov, ne pa tudi njihovo zbiranje ali vezava.