FrancophonIA/ELRC3.0 huggingface dataset:
English: These include potassium supplements or salt substitutes containing potassium, potassium-sparing medicines and heparin.
Slovenian: To vklju uje kalijeve nadomestke ali nadomestke soli, ki vsebujejo kalij, zdravila, ki var ujejo s kalijem in heparin.
English: Caution required with concomitant use
Slovenian: Pri so asni uporabi je potrebna previdnost
English: Clinical experience in children less than 6 years of age Two clinical studies were conducted in patients aged 1 to 6 years with 90 and 75 patients, respectively.
Slovenian: Pri bolnikih v starosti od 1 leta do 6 let so izvedli dve klini ni študiji: v eno je bilo vklju enih 90 bolnikov, v drugo pa 75.
English: Regarding renal function, doubling of serum creatinine was observed in 4.2% of valsartan-treated patients, 4.8% of valsartan+captopril-treated patients, and 3.4% of captopril-treated patients.
Slovenian: Glede delovanja ledvic so opazili podvojitev koncentracije kreatinina v serumu pri 4,2 % bolnikov, ki so se zdravili z valsartanom, pri 4,8 % bolnikov, ki so se zdravili s kombinacijo valsartana in kaptoprila, in pri 3,4 % bolnikov, ki so se zdravili s kaptoprilom.
English: In the overall Val-HeFT population, valsartan treated patients showed significant improvement in NYHA class, and heart failure signs and symptoms, including dyspnoea, fatigue, oedema and rales compared to placebo.
Slovenian: V celotni populaciji študije Val-HeFT se je pri bolnikih, zdravljenih z valsartanom, pokazalo zna ilno izboljšanje po razvrstitvi NYHA in v znakih ter simptomih sr nega popuš anja, vklju no z dispnejo, utrujenostjo, edemom in s piskanjem pri dihanju v primerjavi s placebom.
English: In patients whose renal function may depend on the activity of the renin-angiotensin system (e.g patients with severe congestive heart failure), treatment with angiotensin converting enzyme inhibitors has been associated with oliguria and/or progressive azotaemia and in rare cases with acute renal failure and/or death.
Slovenian: Pri bolnikih, pri katerih je delovanje ledvic lahko odvisno od aktivnosti renin-angiotenzinskega sistema, (npr. pri bolnikih s hudim kongestivnim sr nim popuš anjem), je bilo zdravljenje z zaviralcem angiotenzinske konvertaze povezano z oligurijo in/ali s progresivno azotemijo, v redkih primerih tudi z akutno odpovedjo ledvic in/ali s smrtjo.
English: The VALsartan In Acute myocardial iNfarcTion trial (VALIANT) was a randomised, controlled, multinational, double-blind study in 14,703 patients with acute myocardial infarction and signs, symptoms or radiological evidence of congestive heart failure and/or evidence of left ventricular systolic dysfunction (manifested as an ejection fraction 40% by radionuclide ventriculography or 35% by echocardiography or ventricular contrast angiography).
Slovenian: VALIANT (VALsartan In Acute myocardial iNfarcTion) je bilo randomizirano, kontrolirano, multinacionalno, dvojno slepo preskušanje, v katerem je sodelovalo 14.703 bolnikov z akutnim miokardnim infarktom, ki so imeli znake, simptome ali radiološke dokaze kongestivnega sr nega popuš anja in/ali znake sistoli ne disfunkcije levega prekata (kar se kaže kot iztisna frakcija 40 % pri radionuklidni ventrikulografiji ali 35 % pri ehokardiografiji ali kontrastni angiografiji prekata).
English: The recommended starting dose of Diovan is 40 mg twice daily.
Slovenian: Priporo en za etni odmerek zdravila Diovan je 40 mg dvakrat na dan.
English: Valsartan is unlikely to be removed by haemodialysis.
Slovenian: Ni verjetno, da bi se valsartan lahko izloil s hemodializo.
English: Concomitant use not recommended
Slovenian: So asna uporaba ni priporo ena
English: Therefore, the combination of valsartan with an ACE inhibitor is not recommended.
Slovenian: Zato uporaba kombinacije valsartana z zaviralcem ACE ni priporo ena.
English: At 30 weeks, the percentage change in UAE was significantly reduced by 36% from baseline with valsartan 160 mg (95%CI: 22 to 47%), and by 44% with valsartan 320 mg (95%CI: 31 to 54%).
Slovenian: Po 30 tednih je bila z valsartanom 160 mg sprememba izlo anja albumina z urinom v odstotkih zna ilno manjša za 36 % od izhodiš ne vrednosti (95 % IZ: 22 do 47 %), z valsartanom 320 mg pa za 44 % (95 % IZ: 31 do 54 %).
English: • increase of level of blood urea nitrogen and increase of level of serum creatinine (which can indicate abnormal kidney function)
Slovenian: • zvišana koncentracija dušika se nine v krvi in zvišana koncentracija kreatinina v serumu (kar lahko kaže na nenormalno delovanje ledvic)
English: Children weighing between 18 kg and <35 kg received valsartan 80 mg or enalapril 10 mg; those between 35 kg and <80 kg received valsartan 160 mg or enalapril 20 mg; those 80 kg received valsartan 320 mg or enalapril 40 mg.
Slovenian: Otroci s telesno maso med 18 in < 35 kg so prejemali valsartan v odmerku 80 mg ali enalapril v odmerku 10 mg; tisti s telesno maso med 35 kg in < 80 kg so prejemali valsartan v odmerku 160 mg ali enalapril v odmerku 20 mg; tisti s telesno maso 80 kg pa so prejemali valsartan v odmerku 320 mg ali enalapril v odmerku 40 mg.
English: Patients treated with valsartan had a better quality of life as demonstrated by change in the Minnesota Living with Heart Failure Quality of Life score from baseline at endpoint than placebo.
Slovenian: Bolniki z valsartanom so imeli ob zaklju ku študije boljšo kakovost življenja v primerjavi s tistimi, ki so prejemali placebo, kot je pokazala sprememba rezultata Minnesotske lestvice kakovosti življenja za bolnike s sr nim popuš anjem od izhodiš a do konca študije (Minnesota Living with Heart Failure Quality of Life).
English: Uptitration to 80 mg and 160 mg twice daily should be done at intervals of at least two weeks to the highest dose, as tolerated by the patient.
Slovenian: Ve anje odmerka na 80 mg in 160 mg dvakrat na dan mora potekati v vsaj dvotedenskim intervalih do najve jega odmerka, glede na to, kako bolnik odmerjanje prenaša.
English: 18 kg to <35 kg
Slovenian: 18 kg do < 35 kg 80 mg
English: However, the triple combination of an ACE inhibitor, a beta blocker and valsartan is not recommended (see sections 4.4 and 5.1).
Slovenian: Vendar trojna kombinacija zaviralca ACE, antagonista adrenergi nih receptorjev beta in valsartana ni priporo ena (glejte poglavji 4.4 in 5.1).
English: Use in paediatric patients aged 6 to 18 years with hepatic impairment As in adults, Diovan is contraindicated in paediatric patients with severe hepatic impairment, biliary cirrhosis and in patients with cholestasis (see sections 4.3, 4.4 and 5.2).
Slovenian: Uporaba pri pediatri nih bolnikih, ki so stari od 6 do 18 let in imajo okvaro jeter Kot pri odraslih je zdravilo Diovan kontraindicirano pri pediatri nih bolnikih s hudo okvaro jeter, z biliarno cirozo in pri bolnikih s holestazo (glejte poglavja 4.3, 4.4 in 5.2).
English: Valsartan was as effective as captopril in reducing all-cause mortality after myocardial infarction.
Slovenian: Valsartan je bil pri zmanjševanju umrljivosti iz vseh vzrokov po miokardnem infarktu enako u inkovit kot kaptopril.
English: There is currently no experience on the safe use in patients with a creatinine clearance <10 ml/min and patients undergoing dialysis, therefore valsartan should be used with caution in these patients.
Slovenian: Trenutno ni izkušenj z varno uporabo pri bolnikih z o istkom kreatinina < 10 ml/min in pri bolnikih, ki se zdravijo z dializo, zato je treba valsartan pri teh bolnikih uporabljati previdno.
English: There is currently no experience on the safe use in patients with a creatinine clearance <10 ml/min and patients undergoing dialysis, therefore valsartan should be used with caution in these patients (see sections 4.2 and
Slovenian: Trenutno ni izkušenj o varni uporabi pri bolnikih z o istkom kreatinina < 10 ml/min in pri bolnikih, ki se zdravijo z dializo, zato je treba pri teh bolnikih valsartan uporabljati previdno (glejte poglavji 4.2 in 4.4).
English: Concomitant use with potassium supplements, potassium-sparing diuretics, salt substitutes containing potassium, or other agents that may increase potassium levels (heparin, etc.) is not recommended.
Slovenian: So asna uporaba kalijevih nadomestkov, diuretikov, ki var ujejo kalij, nadomestkov soli, ki vsebujejo kalij, ali drugih zdravil, ki lahko povzro ijo zve anje koncentracije kalija (heparin, itd.), ni priporo ena.
English: In some patients whose blood pressure is not adequately controlled, the dose can be increased to 160 mg and to a maximum of 320 mg. Diovan may also be administered with other antihypertensive agents.
Slovenian: Bolnikom, pri katerih krvni tlak ni ustrezno urejen, je mogo e odmerek zve ati na 160 mg in na najve 320 mg.
English: In clinical trials where valsartan was compared with an ACE inhibitor, the incidence of dry cough was significantly (p<0.05) less in patients treated with valsartan than in those treated with an ACE inhibitor (2.6% versus 7.9% respectively).
Slovenian: V klini nih preskušanjih, v katerih so valsartan primerjali z zaviralcem ACE, je bila pogostnost suhega kašlja pri bolnikih, ki so prejemali valsartan, statisti no zna ilno manjša kot pri tistih, ki so prejemali zaviralec ACE (2,6 % v primerjavi s 7,9 %, p < 0,05).
English: The study report will be finalized by the first quarter of 2014.
Slovenian: Poro ilo o študiji bo zaklju eno do etrtega etrtletja leta 2010.
English: • if you are taking medicines that increase the amount of potassium in your blood.
Slovenian: • e jemljete zdravila, ki pove ujejo koli ino kalija v krvi.
English: When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately, and, if appropriate, alternative therapy should be started (see sections 4.3 and 4.6).
Slovenian: Ob potrjeni nose nosti je treba zdravljenje z antagonisti angiotenzina II takoj prekiniti in, e je primerno, za eti alternativno zdravljenje (glejte poglavji 4.3 in
English: In a subgroup of patients not receiving an ACE inhibitor (n=366), the morbidity benefits were greatest.
Slovenian: Koristi v zvezi z obolevnostjo so bile najve je v podskupini bolnikov, ki niso prejemali zaviralca ACE (n = 366).
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential.
Slovenian: Neklini ni podatki na osnovi obi ajnih študij farmakološke varnosti, toksi nosti pri ponavljajo ih se odmerkih, genotoksi nosti in karcinogenega potenciala ne kažejo posebnega tveganja za loveka.
English: The MARVAL (Micro Albuminuria Reduction with Valsartan) study assessed the reduction in urinary albumin excretion (UAE) with valsartan (80-160 mg/od) versus amlodipine (5-10 mg/od), in 332 type 2 diabetic patients (mean age: 58 years; 265 men) with microalbuminuria (valsartan: 58 µg/min; amlodipine: 55.4 µg/min), normal or high blood pressure and with preserved renal function (blood creatinine <120 µmol/l).
Slovenian: V študiji MARVAL (Zmanjšanje mikroalbuminurije z valsartanom - Micro Albuminuria Reduction with Valsartan) so ocenili zmanjšanje izlo anja albumina z urinom (urinary albumin excretion - UAE) z valsartanom (v odmerku 80-160 mg/enkrat na dan) v primerjavi z amlodipinom ( v odmerku 5-10 mg/enkrat na dan), pri 332 bolnikih s sladkorno boleznijo tipa 2 (povpre na starost: 58 let; 265 moških) z mikroalbuminurijo (v skupini z valsartanom: 58 µg/min; v skupini z amlodipinom: 55,4 µg/min), z normalnim ali zvišanim krvnim tlakom in z ohranjenim delovanjem ledvic (koncentracija kreatinina v krvi < 120 µmol/l).
English: MARKETING AUTHORISATION HOLDER [See Annex I - To be completed nationally]
Slovenian: IMETNIK DOVOLJENJA ZA PROMET [Glejte Dodatek I - Izpolni država lanica]
English: In most patients, after administration of a single oral dose, onset of antihypertensive activity occurs within 2 hours, and the peak reduction of blood pressure is achieved within 4-6 hours.
Slovenian: Pri ve ini bolnikov pride do antihipertenzivnega u inka v 2 urah po vnosu posami nega peroralnega odmerka, do najve jega znižanja krvnega tlaka pa pride v 4 do 6 urah.
English: ADRs that occurred in adult patients with post-myocardial infarction and/or heart failure patients are listed below.
Slovenian: Neželeni u inki, ki so se pojavljali pri odraslih bolnikih po miokardnem infarktu in/ali pri bolnikih s sr nim popuš anjem, so navedeni spodaj:
English: In patients with heart failure, the triple combination of an ACE inhibitor, a beta blocker and Diovan has not shown any clinical benefit (see section 5.1).
Slovenian: Pri bolnikih s sr nim popuš anjem uporaba trojne kombinacija zaviralca ACE, antagonista adrenergi nih receptorjev beta in zdravila Diovan ni pokazala klini nih koristi (glejte poglavje 5.1).
English: Use in paediatric patients aged 6 to 18 years with renal impairment Use in paediatric patients with a creatinine clearance <30 ml/min and paediatric patients undergoing dialysis has not been studied, therefore valsartan is not recommended in these patients.
Slovenian: Uporaba pri pediatri nih bolnikih, ki so stari od 6 do 18 let in imajo okvaro ledvic Pri pediatri nih bolnikih z o istkom kreatinina < 30 ml/min in pri pediatri nih bolnikih, ki se zdravijo z dializo, uporabe valsartana niso prou evali, zato pri teh bolnikih ni priporo ena.
English: Children and adolescents (6 to 18 years of age) with high blood pressure In patients who weigh less than 35 kg the usual dose is 40 mg of valsartan once daily.
Slovenian: Otroci in mladostniki (stari od 6 do 18 let) z visokim krvnim tlakom Za bolnike s telesno maso pod 35 kg je obi ajni odmerek 40 mg valsartana enkrat na dan. Za bolnike s telesno maso 35 kg ali ve je obi ajni za etni odmerek 80 mg valsartana enkrat na dan.
English: Clinical experience in children at or above 6 years of age In a clinical study involving 261 hypertensive paediatric patients 6 to 16 years of age, patients who weighed <35 kg received 10, 40 or 80 mg of valsartan tablets daily (low, medium and high doses), and patients who weighed 35 kg received 20, 80, and 160 mg of valsartan tablets daily (low, medium and high doses).
Slovenian: V klini ni študiji, v katero je bilo vklju enih 261 hipertenzivnih pediatri nih bolnikov v starosti od 6 do 16 let, so bolniki s telesno maso < 35 kg v obliki tablet prejemali 10, 40 ali 80 mg valsartana na dan (nizke, srednje ali visoke odmerke), bolniki s telesno maso 35 kg pa so v obliki tablet prejemali 20, 80 ali 160 mg valsartana na dan (nizke, srednje ali visoke odmerke).
English: The average time to peak concentration and elimination half-life of valsartan in heart failure patients are similar to that observed in healthy volunteers.
Slovenian: Povpre ni as do najvišje koncentracije in razpolovni as izlo anja valsartana pri bolnikih s sr nim popuš anjem sta podobna kot pri zdravih prostovoljcih.
English: As in adults, Diovan is contraindicated in paediatric patients with severe hepatic impairment, biliary cirrhosis and in patients with cholestasis (see sections 4.3 and 5.2).
Slovenian: Kot pri odraslih je zdravilo Diovan kontraindicirano pri pediatri nih bolnikih s hudo okvaro jeter, z biliarno cirozo in pri bolnikih s holestazo (glejte poglavji 4.3 in 5.2).
English: The Diovan Reduction of Proteinuria (DROP) study further examined the efficacy of valsartan in reducing UAE in 391 hypertensive patients (BP=150/88 mmHg) with type 2 diabetes, albuminuria (mean=102 µg/min; 20-700 µg/min) and preserved renal function (mean serum creatinine = 80 µmol/l).
Slovenian: V študiji zmanjševanja proteinurije z zdravilom Diovan (Diovan Reduction of Proteinuria - DROP) so naprej preu evali u inkovitost valsartana pri zmanjšanju izlo anja albumina z urinom pri 391 hipertenzivnih bolnikih (s krvnim tlakom 150/88 mmHg), s sladkorno boleznijo tipa 2, z albuminurijo (v povpre ju 102 µg/min; v obsegu 20-700 µg/min) in z ohranjenim delovanjem ledvic (s povpre no koncentracijo kreatinina v serumu 80 µmol/l).
English: When pregnancy is diagnosed, treatment with AIIRAs should be stopped immediately, and, if appropriate, alternative therapy should be started.
Slovenian: Ob potrjeni nose nosti je treba zdravljenje z antagonisti angiotenzina II takoj prekiniti in, e je primerno, za eti alternativno zdravljenje.
English: Treatment of symptomatic heart failure in adult patients when Angiotensin Converting Enzyme (ACE) inhibitors cannot be used, or as add-on therapy to ACE inhibitors when beta blockers cannot be used (see sections 4.4 and 5.1).
Slovenian: Zdravljenje simptomatskega sr nega popuš anja pri odraslih bolnikih v primerih, ko ni mogo e uporabiti zaviralcev angiotenzinske konvertaze (ACE), ali kot dodatno zdravljenje poleg zaviralcev ACE, ko ni mogo e uporabiti antagonistov adrenergi nih receptorjev beta (glejte poglavji 4.4 in 5.1).
English: The effect of the treatment can be influenced if Diovan is taken together with certain other medicines.
Slovenian: So asno jemanje nekaterih drugih zdravil lahko vpliva na u inek zdravljenja z zdravilom Diovan.
English: There is limited clinical experience with Diovan in paediatric patients with mild to moderate hepatic impairment.
Slovenian: Obseg klini nih izkušenj z uporabo zdravila Diovan pri pediatri nih bolnikih z blago do zmerno okvaro jeter je omejen.
English: During repeated dosing, the antihypertensive effect is substantially present within 2 weeks, and maximal effects are attained within 4 weeks and persist during long-term therapy.
Slovenian: Po ve kratnem odmerjanju pride do znatnega znižanja krvnega tlaka v 2 tednih, v 4 tednih pa do najve jega u inka, ki se med dolgotrajnim zdravljenjem ohranja.
English: Treatment of essential hypertension in adults, and hypertension in children and adolescents 6 to 18 years of age.
Slovenian: Zdravljenje esencialne hipertenzije pri odraslih in hipertenzije pri otrocih in mladostnikih, starih od 6 do 18 let.
English: If the combination proves necessary, careful monitoring of serum lithium levels is recommended.
Slovenian: e se izkaže, da je so asna uporaba obeh zdravil nujna, je priporo eno skrbno spremljanje koncentracije litija v serumu.
English: ANNEX II AMENDMENTS TO SUMMARY OF PRODUCT CHARACTERISTICS AND PACKAGE LEAFLET
Slovenian: DODATEK II DOPOLNILA POVZETKA GLAVNIH ZNA ILNOSTI ZDRAVILA IN NAVODILA ZA UPORABO
English: Provas 40 mg 40 mg
Slovenian: Provas 40 mg
English: Val-HeFT was a randomised, controlled, multinational clinical trial of valsartan compared with placebo on morbidity and mortality in 5,010 NYHA class II (62%), III (36%) and IV (2%) heart failure patients receiving usual therapy with LVEF <40% and left ventricular internal diastolic diameter (LVIDD) >2.9 cm/m2.
Slovenian: Val-HeFT je bilo randomizirano, kontrolirano, multinacionalno klini no preskušanje valsartana v primerjavi s placebom glede obolevnosti in umrljivosti pri 5.010 bolnikih s sr nim popuš anjem razreda NYHA II (62 %), III (36 %) in IV (2 %), ki so prejemali obi ajno terapijo in so imeli iztisni delež levega prekata < 40 % in notranji diastoli ni premer levega prekata (left ventricular internal diastolic diameter - LVIDD) > 2,9 cm/m2.
English: • Tell your doctor if you are breast-feeding or about to start breast-feeding.
Slovenian: • Povejte svojemu zdravniku, e dojite ali nameravate za eti dojiti.
English: The mean duration of follow-up was nearly two years.
Slovenian: Bolnike so v povpre ju spremljali skoraj dve leti.
English: Hypertension Treatment of hypertension in children and adolescents 6 to 18 years of age.
Slovenian: Hipertenzija Zdravljenje hipertenzije pri otrocih in mladostnikih, starih od 6 do 18 let.
English: • decreased kidney function (signs of renal impairment)
Slovenian: • zmanjšano delovanje ledvic (znak ledvi ne okvare)
English: Provas 80 mg 80 mg
Slovenian: Provas 80 mg
English: Diovan is contraindicated in patients with severe hepatic impairment, biliary cirrhosis and in patients with cholestasis (see sections 4.3, 4.4 and 5.2).
Slovenian: Zdravilo Diovan je kontraindicirano pri bolnikih s hudo okvaro jeter, z biliarno cirozo in pri bolnikih s holestazo (glejte poglavja 4.3, 4.4 in 5.2).
English: At the end of 2 weeks, valsartan reduced both systolic and diastolic blood pressure in a dose-dependent manner.
Slovenian: Po dveh tednih je valsartan v odvisnosti od odmerka znižal tako sistoli ni kot diastoli ni krvni tlak.
English: Rixil 40 mg 40 mg
Slovenian: Rixil 40 mg
English: Evaluation of patients with heart failure should always include assessment of renal function (see section 4.2).
Slovenian: Pregled bolnikov po miokardnem infarktu mora vedno vklju evati oceno ledvi ne funkcije (glejte poglavje 4.2).
English: Marketing Authorisation Holder and Manufacturer [See Annex I - To be completed nationally]
Slovenian: Imetnik dovoljenja za promet z zdravilom in izdelovalec [Glejte Dodatek I - Izpolni država lanica]
English: Blood and lymphatic system disorders Not known
Slovenian: Bolezni krvi in limfati nega sistema neznana trombocitopenija
English: These doses in rats (200 and 600 mg/kg/day) are approximately 6 and 18 times the maximum recommended human dose on a mg/m2 basis (calculations assume an oral dose of 320 mg/day and a 60-kg patient).
Slovenian: Ti odmerki pri podganah (200 do 600 mg/kg/dan) so približno 6-krat in 18-krat ve ji od najve jega priporo enega odmerka za ljudi na osnovi mg/m2 (izra un predvideva peroralni odmerek 320 mg/dan in 60-kg bolnika).
English: Provas 320 mg 320 mg
Slovenian: Provas 320 mg
English: Use of Diovan in post-myocardial infarction patients commonly results in some reduction in blood pressure, but discontinuation of therapy because of continuing symptomatic hypotension is not usually necessary provided dosing instructions are followed (see section 4.2).
Slovenian: Uporaba zdravila Diovan pri bolnikih po miokardnem infarktu pogosto povzro i dolo eno znižanje krvnega tlaka, vendar zaradi vztrajne simptomatske hipotenzije obi ajno ni potrebno prekiniti zdravljenja, e bolnik uporablja zdravilo v skladu z navodili za odmerjanje (glejte poglavje 4.2).
English: Adult patients after a recent heart attack: After a heart attack the treatment is generally started as early as after 12 hours, usually at a low dose of 20 mg twice daily.
Slovenian: Odrasli bolniki po nedavnem sr nem napadu: Po sr nem napadu zdravljenje ve inoma za nemo že 12 ur po napadu z nizkimi odmerki 20 mg dvakrat na dan. Odmerek 20 mg dobite tako, da razpolovite 40-miligramsko tableto.
English: • if you are being treated for heart failure, a triple combination with ACE inhibitors and beta blockers (medications to treat heart failure) is not recommended.
Slovenian: e se zdravite zaradi srnega popušanja, ni priporoena uporaba trojne kombinacija z zaviralci ACE in antagonisti adrenerginih receptorjev beta (zdravila za zdravljenje srnega popušanja).
English: Rua do Centro Empresarial, Edificio 8 Quinta da Beloura
Slovenian: Quinta da Beloura
English: Angiotensin II Receptor Antagonists (AIIRAs) should not be initiated during pregnancy.
Slovenian: Zdravljenja z antagonisti angiotenzina II se ne sme za eti med nose nostjo.
English: Cordinate 320 mg 320 mg
Slovenian: Cordinate 320 mg
English: Adult patients with heart failure: Treatment starts generally with 40 mg twice daily.
Slovenian: Odrasli bolniki s sr nim popuš anjem: Zdravljenje obi ajno za nemo s 40 mg dvakrat na dan.
English: Provas 160 mg 160 mg
Slovenian: Provas 160 mg
English: These doses in rats (600 mg/kg/day) are approximately 18 times the maximum recommended human dose on a mg/m2 basis (calculations assume an oral dose of 320 mg/day and a 60-kg patient).
Slovenian: Ti odmerki pri podganah (600 mg/kg/dan) so približno 18-krat ve ji od najve jega priporo enega odmerka za ljudi na osnovi mg/m2 (izra un predvideva peroralni odmerek 320 mg/dan in 60-kg bolnika).
English: Diovan is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section).
Slovenian: Uporaba zdravila Diovan ni priporo ljiva v zgodnjem obdobju nose nosti, po tretjem mesecu nose nosti pa lahko povzro i resno škodo vašemu otroku (glejte poglavje Nose nost in dojenje).