FrancophonIA/ELRC3.0 huggingface dataset:
English: This is equivalent to 4.4% of the recommended maximum daily dietary intake of sodium for an adult.
Slovenian: To ustreza 4,4 % priporočenega največjega dnevnega vnosa natrija s hrano za odraslega.
English: The dose and/or frequency of use of these medicines may need to be reduced to avoid hypotension and prolonged erection.
Slovenian: Odmerek in/ali pogostnost uporabe teh zdravil bo morda treba zmanjšati, da bi preprečili hipotenzijo in dolgotrajno erekcijo.
English: Some patients taking ritonavir may experience changes in the electrocardiogram (ECG).
Slovenian: Nekaterim bolnikom, ki jemljejo ritonavir, se lahko pojavijo spremembe na elektrokardiogramu (EKG).
English: A large amount (6100 live births) of pregnant women were exposed to ritonavir during pregnancy; of these, 2800 live births were exposed during the first trimester.
Slovenian: Med nosečnostjo je bilo ritonavirju izpostavljeno veliko število (6100 živorojenih) nosečnic; od tega je bilo 2800 živorojenih izpostavljenih v prvem trimesečju.
English: In this instance, close clinical monitoring is warranted.
Slovenian: V tem primeru je potrebno skrbno klinično spremljanje.
English: ND: Not determined.
Slovenian: ND: Ni določeno.
English: Renal clearance averaged less than 0.1 l/h and was relatively constant throughout the dosage range.
Slovenian: Ledvični očistek je bil v povprečju manj kot 0,1 l/uro in je bil v vsem odmernem območju razmeroma stalen.
English: Your doctor may wish to reduce the steroid dose or monitor your side effects more closely.
Slovenian: Zdravnik vam bo morda zmanjšal odmerek steroida ali pa bo natančneje spremljal vaše neželene učinke.
English: Tissue distribution studies with
Slovenian: Raziskave porazdelitve v tkivih s
English: There is no parenteral formulation of ritonavir, therefore the extent of absorption and absolute bioavailability have not been determined.
Slovenian: Parenteralnega pripravka ritonavirja ni, zato delež absorpcije in absolutna biološka uporabnost nista ugotovljeni.
English: ND: Not determined
Slovenian: ND: ni določeno
English: Response was similar in both dosing regimens and across patient age.
Slovenian: Odziv je bil podoben pri obeh shemah odmerjanja in ne glede na starost bolnika.
English: Ritonavir penetrates minimally into the brain.
Slovenian: Ritonavir minimalno prodira v možgane.
English: Also read the list of medicines under ‘Other medicines and Ritonavir Mylan' for use with certain other medicines which require special care.
Slovenian: Preberite tudi seznam zdravil pod naslovom ''Druga zdravila in zdravilo Ritonavir Mylan'' glede uporabe z nekaterimi drugimi zdravili, ki zahtevajo posebno pozornost.
English: Even if you feel better, do not stop taking Ritonavir Mylan without talking to your doctor.
Slovenian: Tudi če se počutite bolje, ne prenehajte jemati zdravila Ritonavir Mylan, ne da bi se posvetovali s svojim zdravnikom.
English: To avoid transmitting the infection, mothers with HIV must not breast-feed their babies.
Slovenian: Da bi preprečili prenos okužbe, matere, ki so okužene s HIV, ne smejo dojiti.
English: Other pharmaceutical forms/strengths may be more appropriate for administration to this population.
Slovenian: Za to populacijo so morda bolj primerne druge farmacevtske oblike/jakosti.
English: If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Slovenian: Če se bolezen jeter pri takšnih bolnikih poslabša, pride v poštev prekinitev ali prenehanje zdravljenja.
English: It is recommended that a condom or other non-hormonal method of contraception is used instead.
Slovenian: Priporočljivo je, da namesto tega uporabljate kondome ali druge nehormonske načine kontracepcije.
English: This medicine contains 87.75 mg of sodium in each tablet.
Slovenian: To zdravilo vsebuje 87,75 mg natrija v vsaki tableti.
English: Accumulation of other mutations in the protease gene (including at positions 20, 33, 36, 46, 54, 71, and 90) can also contribute to ritonavir resistance.
Slovenian: K odpornosti proti ritonavirju lahko pripomore tudi kopičenje drugih mutacij na proteaznem genu (vključno s položaji 20, 33, 36, 46, 54, 71 in 90).
English: Erectile dysfunction, as the medicines used to treat erectile dysfunction can cause hypotension and prolonged erection.
Slovenian: erektilno disfunkcijo, saj zdravila, ki se uporabljajo za zdravljenje erektilne disfunkcije lahko povzročijo hipotenzijo in dolgotrajno erekcijo.
English: In general, pregnant mothers received ritonavir after the first three months of pregnancy at a lower dose (booster) along with other protease inhibitors.
Slovenian: Na splošno so nosečnice dobivale ritonavir po prvih treh mesecih nosečnosti v manjšem (spodbujevalnem) odmerku skupaj z drugimi zaviralci proteaz.
English: The extent of increase in AUC and Cmax depends on the timing of ritonavir administration.
Slovenian: Obseg povečanja AUC in Cmax je odvisen od časa uporabe ritonavirja.
English: If you are affected do not drive or use machinery.
Slovenian: Če se vam to zgodi, ne upravljajte vozil in strojev.
English: Stevens Johnson syndrome, toxic epidermal necrolysis (TEN)
Slovenian: Stevens-Johnsonov sindrom, toksična epidermalna nekroliza (TEN)
English: Food slightly decreases the bioavailability of the ritonavir tablet.
Slovenian: Hrana nekoliko zmanjša biološko uporabnost tablet ritonavirja.
English: Dizziness is a known undesirable effect that should be taken into account when driving or using machinery.
Slovenian: Omotica je znan neželeni učinek, ki ga je treba upoštevati, kadar naj bi bolnik vozil oz. upravljal s stroji.
English: Contraindicated when used for the treatment of pulmonary arterial hypertension (PAH) only.
Slovenian: Kontraindiciran je le, kadar se uporablja za zdravljenje pljučne arterijske hipertenzije (PAH).
English: (μg•h/ml) t1/2 (h)
Slovenian: (μg•uro/ml) t1/2 (ure)
English: The effect of ritonavir on rifampicin is not known.
Slovenian: Vpliv ritonavirja na rifampcin ni znan.
English: Clozapine, pimozide
Slovenian: Klozapin, pimozid
English: When ritonavir is used as a pharmacokinetic enhancer at the 100 mg and 200 mg level it cannot be assumed that the following warnings and precautions will also apply.
Slovenian: Če je ritonavir uporabljen kot farmakokinetični stopnjevalec v odmerkih 100 mg in 200 mg, ni mogoče domnevati, da prav tako veljajo naslednja opozorila in previdnostni ukrepi.
English: Patients with chronic diarrhoea or malabsorption
Slovenian: Bolniki s kronično drisko ali malabsorpcijo
English: This medicinal product contains 87.75 mg sodium per tablet, equivalent to 4.4% of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Slovenian: To zdravilo vsebuje 87,75 mg natrija na tableto, kar ustreza 4,4 % priporočenega največjega dnevnega vnosa s strani Svetovne zdravstvene organizacije (WHO), ki je 2 g natrija za odrasle.
English: 150 daily
Slovenian: 150 na dan
English: In some cases fatalities have been observed.
Slovenian: Opisanih je bilo nekaj smrtnih primerov.
English: 1 Based on parallel group comparison.
Slovenian: Na podlagi primerjave vzporednih skupin.
English: S-Warfarin R-Warfarin
Slovenian: Varfarin S-varfarin R-varfarin
English: However, the AUC of the M-2 metabolite was approximately 3% of the AUC of parent compound.
Slovenian: Vendar je AUC presnovka M-2 le približno 3 % AUC matične učinkovine.
English: Ritonavir Mylan is used by children 2 years of age or older, adolescents and adults who are infected with HIV, the virus which causes AIDS.
Slovenian: Zdravilo Ritonavir Mylan se uporablja pri otrocih, starih 2 leti ali več, mladostnikih in odraslih, ki so okuženi s HIV, virusom, ki povzroča AIDS.
English: Long term carcinogenicity studies of ritonavir in mice and rats revealed tumourigenic potential specific for these species, but are regarded as of no relevance for humans.
Slovenian: Dolgotrajne raziskave kancerogenosti ritonavirja na miših in podganah so odkrile tumorogeni potencial, specifičen za ti živalski vrsti, ki pa velja za nepomembnega pri ljudeh.
English: There may be additional information in those leaflets about situations when ritonavir should be avoided.
Slovenian: V teh navodilih so morda dodatne informacije o okoliščinah, v katerih ne smete jemati ritonavirja.
English: If you have any further questions about Ritonavir Mylan (ritonavir) or the other medicines prescribed, please ask your doctor or pharmacist.
Slovenian: Če imate dodatna vprašanja o zdravilu Ritonavir Mylan (ritonavirju) ali drugih predpisanih zdravilih, se posvetujte z zdravnikom ali s farmacevtom.
English: If you are currently taking any of these medicines, ask your doctor about switching to a different medicine while you are taking Ritonavir Mylan.
Slovenian: Če trenutno jemljete katero od teh zdravil, se z zdravnikom pogovorite o zamenjavi s kakšnim drugačnim zdravilom, medtem ko uporabljate zdravilo Ritonavir Mylan.
English: Do not take Ritonavir Mylan if you are allergic to ritonavir or any of the other ingredients of this medicine (see section 6).
Slovenian: Ne jemljite zdravila Ritonavir Mylan če ste alergični na ritonavir ali katerokoli sestavino tega zdravila (glejte poglavje 6).
English: Kidney (renal) disease, since your doctor may need to check the dose of your other medicines (such as protease inhibitors).
Slovenian: bolezen ledvic, ker bo zdravnik morda moral preveriti odmerek vaših drugih zdravil (npr. zaviralcev proteaz).
English: Dose adjustment should be considered based on the patient's clinical response to methadone therapy.
Slovenian: Odmerek je treba prilagoditi glede na bolnikov klinični odziv na zdravljenje z metadonom.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/17/1242/001 30 film-coated tablets EU/1/17/1242/002 90 film-coated tablets EU/1/17/1242/003 100 film-coated tablets
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/17/1242/001 30 filmsko obloženih tablet EU/1/17/1242/002 90 filmsko obloženih tablet EU/1/17/1242/003 100 filmsko obloženih tablet
English: Dose alterations should not be necessary.
Slovenian: Spreminjanje odmerka praviloma ni potrebno.
English: Ritonavir did not appear to increase the chance of developing birth defects compared to the general population.
Slovenian: Glede na izkušnje ritonavir ni povečal možnosti za pojav prirojenih hib v primerjavi s splošno populacijo.
English: The maximum daily dose of this product is equivalent to 53% of the WHO recommended maximum daily intake for sodium.
Slovenian: Največji dnevni odmerek tega zdravila ustreza 53 % priporočenega največjega dnevnega vnosa za natrij s strani Svetovne zdravstvene organizacije (WHO).
English: Methadone1
Slovenian: Metadon1
English: So it is important that you carefully read the side effects section of the leaflets that are provided with these other medicines.
Slovenian: Zato je pomembno, da natančno preberete poglavje o neželenih učinkih v navodilih, priloženih tem drugim zdravilom.
English: • serious allergic reaction (anaphylaxis) • high levels of sugar in the blood
Slovenian: - resna alergijska reakcija (anafilaksija), - visoka koncentracija sladkorja v krvi.
English: The most frequently used nucleosides in this study were zidovudine, stavudine, didanosine and zalcitabine.
Slovenian: Najpogosteje uporabljani nukleozidi v tej študiji so bili zidovudin, stavudin, didanozin in zalcitabin.
English: Erythromycin, itraconazole
Slovenian: Eritromicin, itrakonazol
English: The increases of plasma levels of buprenorphine and its active metabolite did not lead to clinically significant pharmacodynamic changes in a population of opioid tolerant patients.
Slovenian: Višja koncentracija buprenorfina in njegovega aktivnega presnovka v plazmi ni povzročila klinično pomembnih farmakodinamičnih sprememb v populaciji bolnikov s toleranco za opioide.
English: No clinically significant differences in AUC or Cmax were noted between males and females.
Slovenian: Med ženskami in moškimi niso ugotovili klinično pomembnih razlik v AUC ali Cmax.
English: The safety and efficacy of ritonavir in children aged below 2 years has not been established.
Slovenian: Varnost in učinkovitost ritonavirja pri otrocih, mlajših od 2 let ni bila ugotovljena.
English: Limited published data reports that ritonavir is present in human milk.
Slovenian: Dojenje Omejeni objavljeni podatki poročajo, da je ritonavir prisoten v materinem mleku.
English: Sulfamethoxazole/Trimethoprim2
Slovenian: Sulfametoksazol/Trimetoprim2
English: Maraviroc may be given with ritonavir to increase the maraviroc exposure.
Slovenian: Maravirok je mogoče uporabiti z ritonavirjem, da bi dosegli večjo izpostavljenost maraviroku.
English: You may need additional medicine to help your blood clot (factor VIII), in order to control any bleeding.
Slovenian: Morda boste za obvladanje krvavitev potrebovali dodatno zdravilo za strjevanje krvi (faktor VIII).
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2).
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja zdravila je le na recept (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: The AUC of the metabolite prednisolone increased by 37 and 28% after 4 and 14 days ritonavir, respectively.
Slovenian: AUC presnovka prednizolona se je povečala za 37 % po 4 dneh in za 28 % po 14 dneh sočasnega jemanja z ritonavirjem.
English: After ritonavir use for 10 days, no inhibitory effect of ritonavir was observed.
Slovenian: Po 10-dnevni uporabi ritonavirja niso opazili nobenega zaviralnega učinka ritonavirja.
English: Dasatinib, nilotinib, vincristine, vinblastine
Slovenian: Dasatinib, nilotinib , vinkristin, vinblastin
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Slovenian: Če opazite kakšne znake okužbe ali druge simptome, kot so mišična šibkost, šibkost, ki se začenja v dlaneh in stopalih in se premika proti trupu, močno bitje srca (palpitacije), tresavica (tremor) ali hiperaktivnost, nemudoma obvestite vašega zdravnika, da vas bo ustrezno zdravil.
English: Ritonavir concentrations in this study were highly variable and somewhat lower than those obtained in adults receiving 600 mg (approximately 330 mg/m2) twice daily.
Slovenian: Koncentracije ritonavirja so bile v tej študiji zelo spremenljive in nekoliko nižje kot pri odraslih, ki so dobivali 600 mg (približno 330 mg/m2) dvakrat na dan.
English: The use of higher ritonavir doses might alter the safety profile of the combination and therefore is not recommended.
Slovenian: Uporaba večjih odmerkov ritonavirja lahko spremeni varnostne značilnosti kombinacije, zato ni priporočljiva.
English: Post-marketing cases have been reported indicating a potential interaction between ritonavir containing products and levothyroxine.
Slovenian: V obdobju trženja so poročali o primerih, ki kažejo na potencialno interakcijo med zdravili, ki vsebujejo ritonavir, in levotiroksinom.
English: If the benefit is considered to outweigh the risk and ritonavir must be used, reduce the ibrutinib dose to 140 mg and monitor patient closely for toxicity.
Slovenian: Če korist odtehta tveganje in je treba ritonavir uporabiti, zmanjšajte odmerek ibrutiniba na 140 mg in pozorno spremljate bolnika za toksičnost.
English: For a description of the mechanisms and potential mechanisms contributing to the interaction profile of the PIs, see section 4.5.
Slovenian: Za opis mehanizmov in možnih mehanizmov, ki prispevajo k medsebojnemu delovanju zaviralcev proteaz, glejte poglavje 4.5.
English: Taking Ritonavir Mylan as recommended should give you the best chance of delaying resistance to the medicines.
Slovenian: Jemanje zdravila Ritonavir Mylan v skladu s priporočili vam zagotavlja najboljšo možnost za odložitev odpornosti proti zdravilom.
English: SPECIAL STORAGE CONDITIONS Do not store above 30C.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Shranjujte pri temperaturi do 30°C.
English: Trough concentrations of ritonavir decrease over time, possibly due to enzyme induction, but appeared to stabilise by the end of 2 weeks.
Slovenian: Minimalne koncentracije ritonavirja v stanju dinamičnega ravnovesja se sčasoma zmanjšajo, morda zaradi indukcije encimov, a se ob koncu 2. tedna stabilizirajo.
English: Paediatric populations The safety profile of ritonavir in children 2 years of age and older is similar to that seen in adults.
Slovenian: Pediatrična populacija Varnostni profil ritonavirja pri otrocih, starejših od 2 let, je podoben varnostnemu profilu pri odraslih.
English: Ritonavir Mylan film-coated tablets are available in plastic bottles with screw caps containing 30, 90 or 100 tablets and in multipacks of 90 tablets comprising 3 bottles, each containing 30 tablets.
Slovenian: Filmsko obložene tablete Ritonavir Mylan so na voljo v plastenkah z navojnim pokrovčkom, ki vsebujejo 30, 90 ali 100 tablet in v skupnem pakiranju po 90 tablet, ki je sestavljeno iz treh plastenk, od katerih vsaka vsebuje 30 tablet.
English: People with liver disease or hepatitis may have worsening of liver disease.
Slovenian: Bolnikom z boleznijo jeter ali hepatitisom se bolezen jeter lahko poslabša.
English: Events noted as having frequency not known were identified via post-marketing surveillance.
Slovenian: Učinke, ki imajo navedeno pogostnost "neznana", so ugotovili med spremljanjem po začetku trženja zdravila.
English: Thyroid-stimulating hormone (TSH) should be monitored in patients treated with levothyroxine at least the first month after starting and/or ending ritonavir treatment.
Slovenian: Pri bolnikih, ki se zdravijo z levotiroksinom, je treba spremljati ščitnico stimulirajoči hormon (TSH) vsaj prvi mesec po začetku in/ali koncu zdravljenja z ritonavirjem.
English: Increased plasma concentrations of quetiapine which may lead to coma.
Slovenian: Zvišana plazemska koncentracija kvetiapina, kar lahko vodi v komo.
English: The use of higher ritonavir doses may alter the safety profile of atazanavir (cardiac effects, hyperbilirubinemia) and therefore is not recommended.
Slovenian: Uporaba večjih odmerkov ritonavirja lahko spremeni varnostne značilnosti atazanavirja (učinki na srce, hiperbilirubinemija), zato ni priporočljiva.
English: Hormonal contraceptives containing ethinylestradiol as ritonavir may reduce the effectiveness of these medicines.
Slovenian: Hormonske kontraceptive, ki vsebujejo etinilestradiol, ker lahko ritonavir zmanjša učinkovitost teh zdravil.
English: Across dose groups, ritonavir oral clearance (CL/F/m2) was approximately 1.5 to 1.7 times faster in paediatric patients above 2 years of age than in adult subjects.
Slovenian: Pri vseh odmernih skupinah je bil peroralni očistek ritonavirja (Oč/F/m2) približno 1,5- do 1,7-krat hitrejši pri pediatričnih bolnikih, starejših od 2 let, kot pri odraslih preiskovancih.
English: For older children it may be feasible to substitute tablets for the maintenance dose of other pharmaceutical forms.
Slovenian: Pri starejših otrocih je namesto vzdrževalnega odmerka drugih farmacevtskih oblik mogoče uporabiti tablete.
English: For patients with renal impairment, a clarithromycin dose reduction should be considered: for patients with creatinine clearance of 30 to 60 ml/min the dose should be reduced by 50%, for patients with creatinine clearance less than 30 ml/min the dose should be reduced by 75%.
Slovenian: Pri bolnikih z okvaro ledvic pride v poštev zmanjšanje odmerka klaritromicina: bolnikom z očistkom kreatinina od 30 do 60 ml/min je treba odmerek zmanjšati za 50 %, tistim z očistkom kreatinina manj kot 30 ml/min pa za 75
English: ↓ 25% ND
Slovenian: Zidovudin ↓ 25 % ND
English: Administration of a single 100 mg dose of ritonavir tablet with a moderate fat meal (857 kcal, 31% calories from fat) or a high fat meal (907 kcal, 52% calories from fat) was associated with a mean decrease of 20-23% in ritonavir AUC and Cmax.
Slovenian: Uporaba enkratnega 100 mg odmerka ritonavirja z zmerno mastnim obrokom (857 kcal, 31 % kalorij iz maščob) ali zelo mastnim obrokom (907 kcal, 52 % kalorij iz maščob) je bila povezana s povprečnim zmanjšanjem AUC in Cmax ritonavirja za 20-23 %.
English: If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, contact your doctor, pharmacist, Accident and Emergency department or if it is urgent get immediate medical help.
Slovenian: Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika, farmacevta, ambulanto za nujno medicinsko pomoč ali poiščite nujno medicinsko pomoč, če je situacija nujna.
English: In patients who are already taking ritonavir when digoxin is introduced, digoxin should be introduced more gradually than usual.
Slovenian: Pri bolnikih, ki ob uvedbi digoksina že jemljejo ritonavir, je treba digoksin uvesti bolj postopoma kot ponavadi.
English: Your doctor may need to adjust the dose of digoxin and monitor you while you are taking digoxin and Ritonavir Mylan in order to avoid heart problems.
Slovenian: Zdravnik vam bo morda moral prilagoditi odmerek digoksina in vas med sočasno uporabo digoksina in zdravila Ritonavir Mylan spremljati, da ne bi prišlo do težav s srcem.
English: Yellow, capsule shaped film-coated tablet, approximately 19.1 mm x 10.2 mm, debossed with ‘M163' on one side and plain on the other side.
Slovenian: Rumena filmsko obložena tableta v obliki kapsule, velikosti približno 19,1 × 10,2 mm, z vtisnjeno oznako »M163« na eni in brez oznake na drugi strani.
English: The maximum mean (95% upper confidence bound) difference in QTcF from placebo was 5.5 (7.6) for 400 mg twice daily ritonavir.
Slovenian: Največja povprečna razlika (95 % zgornja meja zaupanja) QTcF v primerjavi s placebom je bila 5,5 (7,6) med uporabo ritonavirja 400 mg dvakrat na dan.
English: People taking ritonavir may still develop infections or other illnesses associated with HIV infection or AIDS.
Slovenian: Osebe, ki jemljejo ritonavir, lahko še vedno zbolijo za okužbami ali drugimi boleznimi, povezanimi z okužbo s HIV in AIDS-om.
English: Refer to the colchicine prescribing information.
Slovenian: Glejte informacije o predpisovanju kolhicina.
English: The signs of toxicity observed in animals (mice and rats) included decreased activity, ataxia, dyspnoea and tremors.
Slovenian: Med znaki toksičnosti, ki so jih ugotavljali pri živalih (miših in podganah), so zmanjšana aktivnost, ataksija, dispneja in tremor.
English: Ritonavir can pass into breast milk.
Slovenian: Ritonavirlahko prehaja v materino mleko.
English: PHARMACEUTICAL FORM AND CONTENTS Film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA filmsko obložene tablete
English: Due to the risk of severe hepatotoxicity, saquinavir/ritonavir should not be given together with rifampicin.
Slovenian: Zaradi tveganja za hepatotoksične učinke sakvinavirja/ritonavirja ne smete dajati skupaj z rifampicinom.
English: Store in the original bottle in order to protect from moisture.
Slovenian: Shranjujte v originalni plastenki, da zagotovite zaščito pred vlago.
English: If ritonavir is co-administered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Slovenian: Če ritonavir uporabite sočasno s parenteralnim midazolamom, morate to izvesti v enoti za intenzivno nego (EIN) ali podobnem okolju, ki omogoča natančno klinično spremljanje in ustrezno medicinsko ukrepanje v primeru depresije dihanja in/ali podaljšane sedacije.
English: However, because ritonavir has also been shown to inhibit CYP2B6 in vitro, the recommended dose of bupropion should not be exceeded.
Slovenian: Ker pa je tudi ugotovljeno, da ritonavir in vitro zavira CYP2B6, priporočenega odmerka bupropiona ne smete prekoračiti.