FrancophonIA/ELRC3.0 huggingface dataset:
English: Based on the different elimination pathways of the other NRTIs zidovudine, emtricitabine, stavudine, lamivudine, that are primarily renally excreted, and abacavir for which metabolism is not mediated by CYP450, no interactions are expected for these medicinal compounds and boosted darunavir.
Danish: På baggrund af de forskellige eliminationsveje for de andre NRTI, zidovudin, emtricitabin, stavudin, lamivudin, der primært udskilles via nyrerne, og abacavir, som ikke metaboliseres via CYP, forventes der ikke nogen lægemiddelinteraktioner for disse lægemidler og boostet darunavir.
English: 3 years In-use shelf life after first opening HDPE bottle: 100 days
Danish: 3 år Holdbarhed når HDPE-flasken først er åbnet: 100 dage.
English: How to store Darunavir Mylan Contents of the pack and other information
Danish: Opbevaring af Darunavir Mylan Pakningsstørrelser og yderligere oplysninger
English: - Corticosteroids including betamethasone, budesonide, fluticasone, mometasone, prednisone, triamcinolone.
Danish: - Kortikosteroider, herunder betamethason, budesonid, fluticason, mometason, prednison, triamcinolon.
English: CORTICOSTEROIDS Corticosteroids primarily metabolised by CYP3A (including betamethasone, budesonide, fluticasone, mometasone, prednisone, triamcinolone)
Danish: KORTIKOSTEROIDER Kortikosteroider der primært metaboliseres af CYP3A (herunder betamethason, budesonid, fluticason, mometason, prednison, triamcinolon)
English: Clinical monitoring for central nervous system toxicity associated with increased exposure to efavirenz may be indicated when darunavir co-administered with low dose ritonavir is given in combination with efavirenz.
Danish: Klinisk monitorering for centralnervesystemstoksicitet i forbindelse med øget eksponering for efavirenz kan være indiceret, når darunavir administreret sammen med lavdosis ritonavir gives i kombination med efavirenz.
English: - Darunavir 75 milligram and 150 milligram tablets have been developed for use in children, but can also be used in adults in some cases.
Danish: - Darunavir tabletter på 75 mg og 150 mg er fremstillet til anvendelse til børn, men i nogle tilfælde kan de også bruges til voksne.
English: Darunavir Mylan 75 mg, 150 mg, 300 mg and 600 mg tablets can be used to construct the twice daily 600 mg regimen.
Danish: Darunavir Mylan 75 mg, 150 mg, 300 mg og 600 mg tabletter kan anvendes til at sammensætte regimet med 600 mg to gange dagligt.
English: zoldipem (sedative agents) - Perphenazine, risperidone, thioridazine (to treat psychiatric conditions).
Danish: zoldipem (beroligende midler) - Perphenazin, risperidon, thioridazin (til behandling af psykiske lidelser).
English: Co-administration with CYP3Ametabolised corticosteroids is not recommended unless the potential benefit to the patient outweighs the risk, in which case patients should be monitored for systemic corticosteroid effects.
Danish: Samtidig administration med CYP3A-metaboliserede kortikosteroider anbefales ikke, med mindre den potentielle fordel for patienten opvejer risikoen herved.
English: Other severe side effects were diabetes (common), and inflammation of the pancreas (uncommon).
Danish: Andre alvorlige bivirkninger var diabetes (almindelig) og betændelse i bugspytkirtlen (ikke almindelig).
English: Co-administration with boosted darunavir may cause a large increase in the concentration of these medicines.
Danish: Co-administration med boostet darunavir kan give anledning til en kraftig forøgelse af koncentrationen af disse lægemidler.
English: Rare thrombocytopenia, neutropenia, anaemia, leucopenia increased eosinophil count
Danish: Sjælden trombocytopeni, neutropeni, anæmi, leukopeni forøget eosinofiltal
English: Based on the different elimination pathways of the other NRTIs zidovudine, emtricitabine, stavudine, lamivudine, that are primarily renally excreted, and abacavir for which metabolism is not mediated by CYP450, no interactions are expected for these medicinal compounds and darunavir coadministered with low dose ritonavir.
Danish: På baggrund af de forskellige eliminationsveje for de andre NRTI, zidovudin, emtricitabin, stavudin, lamivudin, der primært udskilles via nyrerne, og abacavir, som ikke metaboliseres via CYP, forventes der ikke nogen lægemiddelinteraktioner for disse lægemidler og darunavir administreret sammen med lavdosis ritonavir.
English: What Darunavir Mylan contains - The active substance is darunavir.
Danish: Darunavir Mylan indeholder - Aktivt stof: darunavir.
English: If you forget to take Darunavir Mylan
Danish: Hvis du glemmer at tage Darunavir Mylan
English: The pharmacokinetic properties of darunavir, co-administered with cobicistat or ritonavir, have been evaluated in healthy adult volunteers and in HIV-1 infected patients.
Danish: De farmakokinetiske egenskaber af darunavir, co-administreret med cobicistat eller ritonavir, er blevet vurderet hos raske, voksne, frivillige forsøgspersoner og hos hiv-1-inficerede patienter.
English: Lurasidone, pimozide, quetiapine or sertindole to treat psychiatric conditions
Danish: Lurasidon,pimozid, quetiapin eller sertindol til behandling af psykiske lidelser
English: Reproductive system and breast disorders Uncommon gynaecomastia*
Danish: Det reproduktive system og mammae Ikke almindelig gynækomasti*
English: rifabutin Cmax darunavir AUC ↑ 53% darunavir Cmin ↑ 68% darunavir Cmax ↑ 39% sum of active moieties of rifabutin (parent drug + 25-O-desacetyl metabolite)
Danish: rifabutin Cmax darunavir AUC ↑ 53% darunavir Cmin ↑ 68% darunavir Cmax ↑ 39% totalt aktivt rifabutin (moderstof + 25-O-desacetyl-metabolit)
English: (↑ clarithromycin from CYP3A inhibition and possible P-gp inhibition)
Danish: (↑ clarithromycin fra CYP3Ahæmning og mulig P-gp-hæmning (Pglykoprotein))
English: People taking darunavir may develop a skin rash.
Danish: Personer, der tager darunavir, kan udvikle hududslæt.
English: This cannot be administered with these 75 milligram tablets.
Danish: Denne dosis kan ikke administreres med disse 75 mg tabletter.
English: HIV Protease inhibitors (PIs) - without additional co-administration of low dose ritonavir Atazanavir
Danish: Proteasehæmmere (PI) -uden yderligere co-administration af lavdosis ritonavir Atazanavir
English: Boosted darunavir may increase antifungal plasma concentrations and posaconazole, isavuconazole, itraconazole or fluconazole may increase darunavir concentrations.
Danish: Boostet darunavir kan øge plasmakoncentrationen af antimykotika , og posaconazol, isavuconazol, itraconazol og fluconazol kan øge koncentrationen af darunavir.
English: In some patients with advanced HIV infection and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Danish: Hos nogle patienter med fremskreden hiv-infektion og en tidligere opportunistisk infektion kan tegn og symptomer på inflammation fra tidligere infektioner vise sig ret hurtigt efter anti-hiv-behandlingen er påbegyndt.
English: ART-naïve paediatric patients (3 to 17 years of age and weighing at least 15 kg) The weight-based dose of darunavir and ritonavir in paediatric patients is provided in the table below.
Danish: ART-naive pædiatriske patienter (3 til 17 år og legemsvægt mindst 15 kg) Den vægtbaserede dosis af darunavir og ritonavir til pædiatriske patienter fremgår af tabellen nedenfor.
English: Limited data is available in patients with HIV-1 clades other than B.
Danish: Der foreligger begrænsede data for patienter med andre hiv-1-subtyper end subtype B.
English: Tell your doctor if you take: - Alfentanil (injectable strong and short-acting painkiller that is used for surgical procedures) - Digoxin (to treat certain heart disorders) - Clarithromycin (antibiotic) - Itraconazole, isavuconazole, fluconazole, posaconazole, clotrimazole (to treat fungal infections).
Danish: Informér din læge, hvis du tager: - Alfentanil (injicerbart stærkt og hurtigtvirkende smertestillende middel, der anvendes til operationer) - Digoxin (til behandling af visse hjertelidelser) - Clarithromycin (antibiotika) - Itraconazol, isavuconazol, fluconazol, posaconazol, clotrimazole (til behandling af svampeinfektioner).
English: atorvastatin Cmax ↑ 319%
Danish: atorvastatin Cmax ↑ 319 % Ω atorvastatin Cmin ND
English: Number of subjects with virologic failure and paired baseline/endpoint phenotypes, showing loss of susceptibility to PIs at endpoint compared to baseline, n/N
Danish: Antal deltagere med virologisk svigt og parrede fænotyper ved baseline/endepunkt, der udviste tab af følsomhed over for PI'er ved endepunktet sammenlignet med baseline, n/N PI
English: Monitoring of renal function may be indicated when darunavir coadministered with low dose ritonavir is given in combination with tenofovir disoproxil, particularly in patients with underlying systemic or renal disease, or in patients taking nephrotoxic agents.
Danish: Monitorering af nyrefunktionen kan være indiceret, når darunavir administreret sammen med lavdosis ritonavir gives i kombination med tenofovirdisoproxil, især hos patienter med underliggende systemisk eller renal sygdom eller hos patienter, der tager nefrotoksiske midler.
English: Darunavir Mylan 75 mg, 150 mg, 300 mg and 600 mg film-coated tablets contain less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium-free'.
Danish: Darunavir Mylan 75 mg, 150 mg, 300 mg og 600 mg filmovertrukne tabletter indeholder mindre end 1 mmol natrium (23 mg) pr. dosis, dvs. den er i det væsentlige natriumfri.
English: ANTIMALARIALS Artemether/Lumefantrine 80/480 mg, 6 doses at 0, 8, 24, 36, 48, and 60 hours artemether AUC ↓ 16% artemether Cmin ↔ artemether Cmax ↓ 18% dihydroartemisinin AUC ↓ 18% dihydroartemisinin Cmin ↔ dihydroartemisinin Cmax ↓ 18% lumefantrine AUC ↑ 175% lumefantrine Cmin ↑ 126% lumefantrine Cmax ↑ 65% darunavir AUC ↔ darunavir Cmin ↓ 13% darunavir Cmax ↔
Danish: MALARIAMIDLER Artemether/ lumefantrin 80/480 mg, 6 doser efter 0, 8, 24, 36, 48 og 60 timer artemether AUC ↓ 16% artemether Cmin ↔ artemether Cmax ↓ 18% dihydroartemisinin AUC ↓ 18% dihydroartemisinin Cmin ↔ dihydroartemisinin Cmax ↓ 18% lumefantrine AUC ↑ 175% lumefantrin Cmin ↑ 126% lumefantrin Cmax ↑ 65% darunavir AUC ↔ darunavir Cmin ↓ 13% darunavir Cmax ↔
English: Ergot alkaloids like ergotamine, dihydroergotamine, ergometrine and methylergonovine to treat migraine headaches
Danish: Ergot-alkaloider (f.eks. ergotamin, dihydroergotamin, ergometrin og methylergometrin)
English: Darunavir Mylan should be used with caution in patients with a known sulphonamide allergy.
Danish: Darunavir indeholder en sulfonamid-del. Darunavir Mylan skal anvendes med forsigtighed hos patienter med kendt sulfonamidallergi.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu .
Danish: Yderligere oplysninger om dette lægemiddel er tilgængelig på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu/.
English: Instructions for children - The child must take darunavir always together with ritonavir.
Danish: Anvisninger for børn - Barnet skal altid tage darunavir sammen med ritonavir.
English: Lopinavir/ ritonavir 800/200 mg per day N=346
Danish: Lopinavir/ ritonavir 800/200 m g pr. dag N=346
English: 100 milligram
Danish: 100 mg
English: Tell your doctor if you take: - Phenobarbital, phenytoin (to prevent seizures) - Dexamethasone (corticosteroid) - Efavirenz (HIV infection) - Boceprevir (hepatitis C infection) - Rifapentine, rifabutin (medicines to treat some infections such as tuberculosis) - Saquinavir (HIV infection).
Danish: Informér din læge, hvis du tager: - Phenobarbital, fenytoin (forhindrer krampeanfald) - Dexamethason (kortikosteroid) - Efavirenz (hiv-infektion) - Boceprevir (hepatitis C-infektion) - Rifapentin, rifabutin (lægemidler til behandling af nogle infektioner som f.eks. tuberkulose) - Saquinavir (hiv-infektion).
English: Pharmacokinetic enhancer and concomitant medications Darunavir has different interaction profiles depending on whether the compound is boosted with ritonavir or cobicistat: - Darunavir boosted with cobicistat is more sensitive for CYP3A induction: concomitant use of darunavir/cobicistat and strong CYP3A inducers is therefore contraindicated (see section 4.3), and concomitant use with weak to moderate CYP3A inducers is not recommended (see section 4.5).
Danish: Farmakokinetisk forstærker og samtidige lægemidler Darunavir har forskellige interaktionsprofiler afhængigt af, om stoffet boostes med ritonavir eller cobicistat: - Darunavir boostet med cobicistat er mere følsomt over for CYP3A-induktion: samtidig brug af darunavir/cobicistat og potente CYP3A-induktorer er derfor kontraindiceret (se pkt.
English: Lovastatin,simvastatin and lomitapide to lower cholesterol levels
Danish: Lovastatin, simvastatin og lomitapid til nedsættelse af kolesterol i blodet
English: The recommended dose regimen is 800 mg once daily with cobicistat 150 mg once daily or ritonavir 100 mg once daily taken with food.
Danish: Den anbefalede dosis er 800 mg en gang dagligt sammen med cobicistat 150 mg en gang dagligt eller ritonavir 100 mg en gang dagligt i forbindelse med et måltid.
English: At week 48, the virologic response, defined as the percentage of patients with confirmed plasma viral load < 50 HIV-1 RNA copies/ml, was evaluated in 16 paediatric patients 15 kg to < 20 kg and 5 paediatric patients 10 kg to < 15 kg receiving darunavir/ritonavir in combination with other antiretroviral agents (see section 4.2 for dosage recommendations per body weight).
Danish: Ved uge 48 blev det virologiske respons, defineret som procentdelen af patienter med bekræftet viral load i plasma < 50 HIV-1-RNA-kopier/ml, evalueret hos 16 pædiatriske patienter med legemsvægt 15 kg til < 20 kg og hos 5 pædiatriske patienter med legemsvægt 10 kg til 15 kg, der fik darunavir/ritonavir i kombination med andre antiretrovirale lægemidler (se pkt.
English: sodium starch glycolate, hypromellose, magnesium stearate.
Danish: natriumcarboxymethylstivelse, hypromellose, magnesiumstearat.
English: Vascular disorders Uncommon hypertension, flushing
Danish: Vaskulære sygdomme Ikke almindelig hypertension, rødmen
English: When administration of atorvastatin and darunavir coadministered with low dose ritonavir is desired, it is recommended to start with an atorvastatin dose of 10 mg once daily.
Danish: Hvis der er behov for administration af atorvastatin og darunavir administreret sammen med lavdosis ritonavir, anbefales det at starte med en atorvastatindosis på 10 mg x 1.
English: Metabolism and nutrition disorders Common anorexia, diabetes mellitus, hypercholesterolaemia, hypertriglyceridaemia, hyperlipidaemia
Danish: Metabolisme og ernæring Almindelig anoreksi, diabetes mellitus, hyperkolesterolæmi, hypertriglyceridæmi, hyperlipidæmi
English: What Darunavir Mylan is and what it is used for What you need to know before you take Darunavir Mylan How to take Darunavir Mylan Possible side effects
Danish: Det skal du vide, før du begynder at tage Darunavir Mylan Sådan tages Darunavir Mylan Mulige bivirkninger
English: Driving and using machines Do not operate machines or drive if you feel dizzy after taking Darunavir Mylan.
Danish: Betjen ikke maskiner, og kør ikke et motorkøretøj, hvis du føler dig svimmel efter at have taget Darunavir Mylan.
English: In-use shelf life after first opening HDPE bottle: 90 days.
Danish: Holdbarhed når HDPE-flasken først er åbnet: 90 dage.
English: ART-experienced paediatric patients (3 to 17 years of age and weighing at least 40 kg) The dose of cobicistat to be used with darunavir in children less than 18 years of age has not been established.
Danish: ART-erfarne pædiatriske patienter (3 til 17 år og legemsvægt mindst 40 kg) Dosis af cobicistat til administration sammen med darunavir hos børn under 18 år, er ikke blevet fastlagt.
English: ART-naïve paediatric patients from the age of 12 years to < 18 years, and weighing at least 40 kg DIONE is an open-label, Phase II trial evaluating the pharmacokinetics, safety, tolerability, and efficacy of darunavir with low dose ritonavir in 12 ART-naïve HIV-1 infected paediatric patients aged 12 to less than 18 years and weighing at least 40 kg.
Danish: ART-naive pædiatriske patienter i alderen 12 år til < 18 år og legemsvægt mindst 40 kg DIONE er et åbent fase II-studie til evaluering af farmakokinetik, sikkerhed, tolerabilitet og effekt af darunavir sammen med lavdosis ritonavir hos 12 ART-naive hiv-1-smittede pædiatriske patienter i alderen 12 år til < 18 år med en legemsvægt på mindst 40 kg.
English: Amiodarone, bepridil, dronedarone, ivabradine, quinidine, ranolazine to treat certain heart disorders e.g. abnormal heart beat
Danish: Amiodaron, bepridil, dronedaron, ivabradin quinidin, ranolazin til behandling af visse hjertelidelser som f.eks. unormal hjerterytme
English: Outcomes at Week 48
Danish: Resultater ved uge 48
English: - The other ingredients are colloidal anhydrous silica, cellulose microcrystalline, crospovidone,
Danish: - Øvrige indholdsstoffer: kolloid vandfri silica, mikrokrystallinsk cellulose, crospovidon,
English: The interaction profile of darunavir depends on whether ritonavir or cobicistat is used as pharmacokinetic enhancer.
Danish: Interaktionsprofilen for darunavir afhænger af, om ritonavir eller cobicistat benyttes som farmakokinetisk forstærker.
English: The maraviroc dose should be 150 mg twice daily when co-administered with boosted darunavir.
Danish: Maraviroc-dosis skal være 150 mg x 2, når det administreres sammen med boostet darunavir.
English: When administered concomitantly with darunavir and low dose ritonavir, the patient's tolerability of bosentan should be monitored.
Danish: Ved samtidig administration sammen med darunavir og lavdosis ritonavir skal patienten monitoreres for tolerabilitet af bosentan.
English: This cannot be administered with these 300 milligram tablets.
Danish: Denne dosis kan ikke administreres med disse 300 mg tabletter.
English: If you notice after 6 hours, then skip the intake and take the next doses as usual.
Danish: Hvis du først opdager det efter 6 timer, skal du springe den dosis over og tage den næste dosis, som du plejer.
English: ● 21 ART-experienced HIV-1 infected paediatric patients aged from 3 to < 6 years and weighing 10 kg to < 20 kg (16 participants from 15 kg to < 20 kg) who received darunavir oral suspension with low dose ritonavir twice daily in combination with other antiretroviral agents.
Danish: ● 21 ART-erfarne hiv-1-smittede pædiatriske patienter i alderen 3 til < 6 år med en legemsvægt på 10 kg til < 20 kg (16 deltagere fra 15 kg til < 20 kg) som fik darunavir oral suspension med lavdosis ritonavir to gange dagligt i kombination med andre antiretrovirale lægemidler.
English: For additional clinical study results in ART-experienced adults and paediatric patients, refer to the Summary of Product Characteristics for darunavir 75 mg, 150 mg, 300 mg or 600 mg tablets.
Danish: Vedrørende yderligere kliniske studieresultater hos ART-erfarne voksne og pædiatriske patienter henvises til produktresuméet for darunavir 75 mg, 150 mg, 300 mg eller 600 mg tabletter.
English: The dosage of other medicines might need to be changed since either their own or darunavir's therapeutic effect or side effects may be influenced when combined.
Danish: Det kan være nødvendigt at ændre doseringen af andre lægemidler, da enten deres eller Darunavir Mylans behandlingsmæssige effekt kan være påvirket, når de kombineres.
English: Applicable to darunavir boosted with either ritonavir or cobicistat: - The combination product lopinavir/ritonavir (see section 4.5).
Danish: Gælder for darunavir boostet med enten ritonavir eller cobicistat: - Kombinationsproduktet lopinavir/ritonavir (se pkt.
English: Caution should be exercised when combining one of these antineoplastic agents with boosted darunavir.
Danish: Der skal udvises forsigtighed ved kombination af et af disse antineoplastiske midler og boostet darunavir.
English: Cmax, ng/ml AUC12h, ng.h/ml Cmin, ng/ml a n=11 for AUC12h
Danish: Cmax, ng/ml AUC12t, ng∙t/ml Cmin, ng/ml b a n=11 for AUC12t
English: CALCIUM CHANNEL BLOCKERS Amlodipine
Danish: CALCIUMANTAGONISTER Amlodipine
English: Co administration of boosted darunavir with clonazepam may increase concentrations of clonazepam.
Danish: Co-administration af boostet med clonazepam kan øge koncentrationen af clonazepam.
English: Instructions for adults - Take darunavir always together with ritonavir.
Danish: Anvisninger for voksne - Tag altid darunavir sammen med ritonavir.
English: When used in combination with darunavir co-administered with low dose ritonavir, dose adjustment of indinavir from 800 mg twice daily to 600 mg twice daily may be warranted in case of intolerance.
Danish: Ved kombination af indinavir og darunavir administreret sammen med lavdosis ritonavir kan dosisjustering af indinavir fra 800 mg x 2 til 600 mg x 2 være nødvendig pga. intolerans.
English: HIV Protease inhibitors (PIs) - with co-administration of low dose ritonavir† Lopinavir/ritonavir
Danish: Proteasehæmmere (PI) - med co-administration af lavdosis ritonavir Lopinavir/ritonavir
English: Darunavir Mylan with food and drink See section 3 ‘How to take Darunavir Mylan.
Danish: Brug af Darunavir Mylan sammen med mad og drikke Se punkt 3 "Sådan skal du tage Darunavir Mylan".
English: Rare acute renal failure, renal failure, nephrolithiasis, increased blood creatinine, proteinuria, bilirubinuria, dysuria, nocturia, pollakiuria decreased creatinine renal clearance
Danish: Sjælden akut nyresvigt, nyresvigt, nephrolitiasis, forhøjet kreatinin i blodet, proteinuri, bilirubinuri, dysuri, nocturi, pollakisuri nedsat kreatininclearance i nyrerne
English: Other forms of this medicine may be more suitable for children: ask your doctor or pharmacist.
Danish: Andre formuleringer af dette lægemiddel kan være mere velegnede til børn.
English: Concomitant use of boosted darunavir and corticosteroids that are metabolised by CYP3A (e.g. fluticasone propionate or other inhaled or nasal corticosteroids) may increase the risk of development of systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression.
Danish: Samtidig administration af boostet darunavir og kortikosteroider, som metaboliseres af CYP3A (f.eks. fluticasonpropionat eller andre inhalerede eller intranasalt administrerede kortikosteroider), kan øge risikoen for udvikling af systemiske kortikosteroidvirkninger, herunder Cushings syndrom og adrenal suppression.
English: A dose decrease may be needed for these drugs when co-administered with boosted darunavir.
Danish: Det kan være nødvendigt at nedsætte dosis af disse lægemidler ved coadministration med boostet darunavir.
English: Caution should be exercised when combining one of these antineoplastic agents with darunavir with low dose ritonavir.
Danish: Der skal udvises forsigtighed ved kombination af et af disse antineoplastiske midler og darunavir med lavdosis ritonavir.
English: EXP <Bottles Only> Once opened, use within 100 days
Danish: EXP <Kun flasker> Skal anvendes inden for 100 dage efter anbrud.
English: Even if you feel better, do not stop taking darunavir and cobicistat or ritonavir without talking to your doctor.
Danish: Selvom du får det bedre, må du ikke stoppe med at tage darunavir og cobicistat eller ritonavir uden først at tale med din læge.
English: - Darunavir Mylan 75 milligram and 150 milligram tablets have been developed for use in children, but can also be used in adults in some cases.
Danish: - Darunavir Mylan-tabletter på 75 mg og 150 mg er fremstillet til anvendelse til børn, men i nogle tilfælde kan de også bruges til voksne.
English: The metabolism of alfentanil is mediated via CYP3A, and may as such be inhibited by darunavir co-administered with low dose ritonavir.
Danish: Alfentanil metaboliseres via CYP3A og kan dermed hæmmes af darunavir coadministreret med lavdosis ritonavir.
English: What Darunavir Mylan contains
Danish: Darunavir Mylan indeholder
English: Based on theoretical considerations darunavir coadministered with cobicistat is expected to increase metformin plasma concentrations.
Danish: Baseret på teoretiske overvejelser forventes darunavir coadministreret med cobicistat at øge plasmakoncentrationen af metformin.