FrancophonIA/ELRC3.0 huggingface dataset:
English: Within the 5 years follow-up post-treatment period, the children had a mean height of 44th percentile, which was below the median of the normative population and less than their mean baseline height (48th percentile).
Croatian: Tijekom petogodišnjeg praćenja nakon završetka liječenja djeca su imala srednju vrijednost visine na 44. percentili, što je bilo niže od medijana vrijednosti normativne populacije i manje od prosjeka njihove visine na početku praćenja (48. percentila).
English: If it gets worse, your doctor will decide whether or not your Ribavirin Teva Pharma B.V. treatment needs to be changed.
Croatian: Ako se infekcija pogoršava, liječnik će odlučiti treba li promijeniti liječenje lijekom Ribavirin Teva Pharma B.V. ili ne.
English: Thus, ribavirin must be administered with caution to patients with pre-existing cardiac disease (see section 4.3).
Croatian: Stoga se ribavirin mora primjenjivati uz oprez u bolesnika s od ranije postojećom srčanom bolešću (vidjeti dio 4.3).
English: Haemoglobin concentrations should be monitored closely during treatment and corrective action taken as necessary (see section 4.2).
Croatian: Potrebno je pažljivo pratiti koncentracije hemoglobina tijekom liječenja i po potrebi poduzeti korektivne mjere (vidjeti dio 4.2).
English: Treatment with ribavirin in combination with peginterferon alfa-2b was associated with decreases in absolute CD4+ cell counts within the first 4 weeks without a reduction in CD4+ cell percentage.
Croatian: Liječenje ribavirinom u kombinaciji s peginterferonom alfa-2b bilo je povezano sa smanjenjem apsolutnog broja CD4+ stanica unutar prva 4 tjedna, no bez smanjenja postotka CD4+ stanica.
English: If the abnormality is reversed, ribavirin may be restarted at 600 mg daily, and further increased to 800 mg daily at the discretion of the treating physician.
Croatian: Ako se vrijednosti vrate u normalu, liječenje ribavirinom može se ponovno započeti dozom od 600 mg na dan, koja se prema odluci nadležnog liječnika može dodatno povećati na 800 mg na dan.
English: There were some cases of more severe neutropenia in patients treated with Ribavirin Teva Pharma B.V. in combination with peginterferon alfa-2b (WHO grade 3: 39 of 186 [21 %]; and WHO grade 4: 13 of 186 [7 %]); WHO grade 3 leukopenia was also reported in 7 % of this treatment group.
Croatian: Bilo je slučajeva teže neutropenije u bolesnika liječenih lijekom Ribavirin Teva Pharma B.V. u kombinaciji s peginterferonom alfa-2b (SZO stupanj 3: 39 od 186 [21%] bolesnika; i SZO stupanj 4: 13 od 186 bolesnika [7%]); leukopenija SZO stupnja 3 također je prijavljena u 7% bolesnika u ovoj terapijskoj skupini.
English: The majority of adverse reactions reported in the study were mild or moderate in severity.
Croatian: Većina nuspojava prijavljenih u ispitivanju bile su blagog do umjerenog intenziteta.
English: If you are not sure, talk to your doctor or pharmacist before taking Ribavirin Teva Pharma B.V. if you: - are allergic to ribavirin or any of the other ingredients of this medicine (listed in section 6).
Croatian: Ako niste sigurni, obratite se svom liječniku ili ljekarniku prije nego uzmete Ribavirin Teva Pharma B.V.: - ako ste alergični na ribavirin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6). - ako ste trudni ili planirate trudnoću (vidjeti dio "Trudnoća i dojenje").
English: Both ribavirin and its triazole carboxamide and triazole carboxylic acid metabolites are also excreted renally.
Croatian: I ribavirin i njegovi metaboliti triazol karboksiamid i triazol karboksilna kiselina izlučuju se putem bubrega.
English: Very rare:
Croatian: vrlo rijetko:
English: Limited safety data (N = 25) are available in co-infected patients with CD4+ cell counts < 200/µL (see section 4.4).
Croatian: Ograničeni su podaci o sigurnosti (N=25) za bolesnike s istodobnom infekcijom u kojih je broj CD4+ stanica <200/µl (vidjeti dio 4.4).
English: Pneumonia, ascariasis, enterobiasis, herpes zoster, cellulitis
Croatian: pneumonija, askarijaza, enterobijaza, herpes zoster, celulitis
English: Hepatomegaly
Croatian: hepatomegalija
English: Patients with low CD4 counts:
Croatian: Bolesnici s malim brojem CD4 stanica:
English: *AUC12 (ng.hr/mL) for Ribavirin; AUC0-24 (IU.hr/mL) for interferon alfa-2b
Croatian: *AUC12 (ng.h/ml) za Ribavirin Teva Pharma B.V ; AUC0-24 (IU.h/ml) za interferon afa-2b
English: Anti-thyroid antibody positive
Croatian: pozitivna antitireoidna protutijela
English: If you are a woman who is breast-feeding, you must not take this medicine.
Croatian: Ako ste dojilja, ne smijete uzimati ovaj lijek.
English: Cerebrovascular haemorrhage*, cerebrovascular ischaemia*, encephalopathy*, polyneuropathy*
Croatian: cerebrovaskularno krvarenje*, cerebrovaskularna ishemija*, encefalopatija*, polineuropatija*
English: If a patient has a serious adverse reaction potentially related to ribavirin, the ribavirin dose should be modified or discontinued, if appropriate, until the adverse reaction abates or decreases in severity.
Croatian: Ako bolesnik ima ozbiljnu nuspojavu koja bi mogla biti povezana s ribavirinom, dozu ribavirina treba prilagoditi ili po potrebi prekinuti njegovu primjenu dok se nuspojava ne povuče ili dok se njezina težina ne smanji.
English: Ribavirin therapy must not be initiated until a report of a negative pregnancy test has been obtained immediately prior to initiation of therapy.
Croatian: Liječenje ribavirinom ne smije se započeti dok se ne dobije negativan rezultat testa na trudnoću neposredno prije početka liječenja.
English: thoughts about threatening the life of others, mania (excessive or unreasonable enthusiasm), pericarditis (inflammation of the lining of the heart), pericardial effusion [a fluid collection that develops between the pericardium (the lining of the heart) and the heart itself], change in colour of the tongue.
Croatian: misli o ugrožavanju života drugih, manija (pretjerano ili bezrazložno ushićenje), perikarditis (upala srčane ovojnice), perikardijalni izljev (nakupljanje tekućine između srčane ovojnice i samog srca), promjena boje jezika
English: The population enrolled mainly consisted in children with mild to moderate hepatitis C. In the two multicentre trials sustained virological response rates in children and adolescents were similar to those in adults.
Croatian: U ispitivanje su uglavnom uključena djeca s blagim do umjerenim hepatitisom C. U dva multicentrična ispitivanja, stope održivog virološkog odgovora u djece i adolescenata bile su slične u onima u odraslih.
English: If the child is weighing less than 47 kg or unable to swallow tablets an oral solution of ribavirin should be used.
Croatian: Ako dijete teži manje od 47 kg ili ako ne može gutati, potrebno je primijeniti oralnu otopinu ribavirina.
English: Among those patients with elevated uric acid levels, very few patients treated with the combination developed clinical gout, none of which required treatment modification or discontinuation from the clinical trials.
Croatian: Među bolesnicima s povišenim vrijednostima mokraćne kiseline vrlo je mali broj onih liječenih kombiniranom terapijom razvio kliničku sliku gihta, a niti u jednog od tih bolesnika nije bilo potrebno modificirati liječenje ili isključiti bolesnika iz ispitivanja.
English: In patients co-infected with HCV/HIV, limited efficacy and safety data (N = 25) are available in subjects with CD4 counts less than 200 cells/µL.
Croatian: Među bolesnicima istodobno zaraženima HCV-om i HIV-om malo je podataka o djelotvornosti i sigurnosti (N=25) za ispitanike s brojem CD4 stanica manjim od 200 stanica/μl.
English: Genotype 1 > 600,000 IU/mL
Croatian: Genotip 1 >600 000 IU/ml svi
English: - Genotoxicity: Ribavirin induces genotoxicity (see section 5.3).
Croatian: - Genotoksičnost: ribavirin inducira genotoksičnost (vidjeti dio 5.3).
English: Patients treated with ribavirin and zidovudine are at increased risk of developing anaemia; therefore, the concomitant use of ribavirin with zidovudine is not recommended (see section 4.5).
Croatian: Bolesnici liječeni ribavirinom i zidovudinom imaju povećan rizik za razvoj anemije, stoga se ne preporučuje istodobna primjena ribavirina sa zidovudinom (vidjeti dio 4.5).
English: Two trials have been conducted in patients co-infected with HIV and HCV.
Croatian: Provedena su dva ispitivanja u bolesnika s istodobnom infekcijom virusima HIV i HCV.
English: Severe adverse reactions were reported in 7 % (8/107) of all subjects and included injection site pain (1 %), pain in extremity (1 %), headache (1 %), neutropenia (1 %), and pyrexia (4 %).
Croatian: Teške nuspojave prijavljene su u 7% svih ispitanika (8/107) i uključivale su bol na mjestu injekcije (1%), bol u udovima (1%), glavobolju (1%), neutropeniju (1%) i pireksiju (4%).
English: Study 1 (RIBAVIC; P01017) was a randomized, multicentre study which enrolled 412 previously untreated adult patients with chronic hepatitis C who were co-infected with HIV.
Croatian: Ispitivanje 1 (RIBAVIC; P01017) bilo je randomizirano, multicentrično kliničko ispitivanje u koje je uključeno 412 prethodno neliječenih odraslih bolesnika s kroničnim hepatitisom C koji su istodobno bili zaraženi HIV-om.
English: Peripheral ischaemia*
Croatian: periferna ishemija*
English: However, in a population pharmacokinetic study, age was not a key factor in the kinetics of ribavirin; renal function is the determining factor.
Croatian: Međutim, u ispitivanju populacijske farmakokinetike dob nije bila ključni čimbenik u kinetici ribavirina.
English: Ninety four of 107 children enrolled in the
Croatian: Devedeset i četiri od 107 djece uključeno je u 5-godišnje dugotrajno ispitivanje praćenja.
English: All Genotype
Croatian: Svi genotipovi svi
English: The sustained response at the end of follow-up was significantly increased by the addition of ribavirin to interferon alfa-2b (41 % vs 16 %, p < 0.001).
Croatian: Trajan odgovor na liječenje na kraju razdoblja praćenja značajno se povećao dodavanjem ribavirina interferonu alfa-2b (41% u odnosu na 16%, p <0,001).
English: Based on published data, single-dose ribavirin pharmacokinetics was altered (increased AUCtf and Cmax) in patients with renal dysfunction compared with control subjects (creatinine clearance > 90 mL/minute).
Croatian: Prema objavljenim podacima, farmakokinetika ribavirina nakon jedne doze bila je izmijenjena (povećani AUCtf i Cmax) u bolesnika s oštećenom funkcijom bubrega u usporedbi s kontrolnim ispitanicima (klirens kreatinina >90 ml/min).
English: Ribavirin is embryotoxic or teratogenic, or both, at doses well below the recommended human dose in all animal species in which studies have been conducted.
Croatian: Ribavirin je pokazao embriotoksične ili teratogene učinke, ili oboje, u svih životinjskih vrsta u kojih su provedena istraživanja pri dozama koje su znatno niže od onih preporučenih za primjenu u ljudi.
English: Light pink to pink, (debossed with “93” on one side and “7232” on the other).
Croatian: Svijetlo ružičasta do ružičasta (s utisnutim "93" na jednoj strani i "7232" na drugoj).
English: Ulcerative colitis*
Croatian: ulcerozni kolitis*
English: Contents of the pack and other information What Ribavirin Teva Pharma B.V. contains
Croatian: Sadržaj pakiranja i druge informacije Što Ribavirin Teva Pharma B.V. sadrži
English: In the treatment phase of this study, the most prevalent adverse reactions in all subjects were pyrexia (80 %), headache (62 %), neutropenia (33 %), fatigue (30 %), anorexia (29 %) and injection-site erythema (29 %).
Croatian: U fazi liječenja u sklopu ovoga ispitivanja nuspojave koje su se najčešće pojavljivale u svih ispitanika bile su pireksija (80%), glavobolja (62%), neutropenija (33%), umor (30%), anoreksija (29%) i eritem na mjestu injekcije (29%).
English: Within the organ system classes, adverse reactions are listed under headings of frequency using the following categories: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥ 1/10,000 to <1/1,000); very rare (<1/10,000); not known.
Croatian: Nuspojave su razvrstane prema organskim sustavima i kategorijama učestalosti definiranima na sljedeći način: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000), nepoznato.
English: Table 2 provides guidelines for dose modifications and discontinuation based on the patient's haemoglobin concentration, cardiac status and indirect bilirubin concentration.
Croatian: Tablici 2 navode se smjernice za prilagodbu doze i prekid primjene na temelju bolesnikove koncentracije hemoglobina, srčanog statusa i koncentracije indirektnog bilirubina.
English: Co-administration of ribavirin and didanosine is not recommended.
Croatian: Ne preporučuje se istodobna primjena ribavirina i didanozina.
English: This should be discussed with your doctor (see “Do not take Ribavirin Teva Pharma B.V.”).
Croatian: O tome morate razgovarati sa svojim liječnikom (vidjeti dio "Nemojte uzimati Ribavirin Teva Pharma B.V.").
English: Study 2 (P02080) was a randomized, single centre study that enrolled 95 previously untreated adult patients with chronic hepatitis C who were coinfected with HIV.
Croatian: Ispitivanje 2 (P02080) bilo je randomizirano ispitivanje provedeno u jednom centru, u koje je uključeno 95 prethodno neliječenih odraslih bolesnika s kroničnim hepatitisom C koji su istodobno bili zaraženi HIV-om.
English: Suicide attempts, panic attack, hallucination
Croatian: pokušaj samoubojstva, napad panike, halucinacija rijetko:
English: In individual cases where the benefit of administering ribavirin concomitantly with azathioprine warrants the potential risk, it is recommended that close hematologic monitoring be done during concomitant azathioprine use to identify signs of myelotoxicity, at which time treatment with these medicines should be stopped (see section 4.4).
Croatian: U pojedinačnim slučajevima, kada korist od uzimanja ribavirina zajedno s azatioprinom opravdava mogući rizik, preporučuje se pomno nadzirati hematološke parametre za vrijeme istodobnog uzimanja azatioprina kako bi se otkrili znakovi mijelotoksičnosti, kada liječenje tim lijekovima treba prekinuti (vidjeti dio 4.4).
English: Rhabdomyolysis*, myositis*
Croatian: rabdomioliza*, miozitis*
English: Note: For patients who weigh <47 kg, or are unable to swallow tablets, ribavirin oral solution is available and should be used if appropriate.
Croatian: Napomena: za bolesnike težine <47 kg, ili one koji ne mogu progutati tabletu, dostupna je ribavirin oralna otopina i potrebno ju je primjenjivati po potrebi.
English: In Study 1 (see section 5.1), decrease in absolute neutrophil count levels below 500 cells/mm3 was observed in 4 % (8/194) of patients and decrease in platelets below 50,000/mm3 was observed in 4 % (8/194) of patients receiving ribavirin in combination with peginterferon alfa-2b.
Croatian: U Ispitivanju 1 (vidjeti dio 5.1) je smanjenje apsolutnog broja neutrofila ispod vrijednosti od 500 stanica/mm3 primjećeno u 4% (8/194) bolesnika, a smanjenje broja trombocita ispod 50 000/mm3 također u 4% (8/194) bolesnika koji su primali ribavirin u kombinaciji s peginterferonom alfa-2b.
English: It is possible that the increased bioavailability in this study was due to delayed transit of ribavirin or modified pH.
Croatian: Moguće je da je povećana bioraspoloživost u ovom ispitivanju bila posljedica odgođenog tranzita ribavirina ili promijenjenog pH.
English: It is possible that the decreased bioavailability in this study was due to delayed transit of ribavirin or modified pH.
Croatian: Moguće je da je smanjena bioraspoloživost u ovom ispitivanju bila posljedica odgođenog tranzita ribavirina ili promijenjenog pH.
English: The mean AUCtf was threefold greater in subjects with creatinine clearance between 10 and 30 mL/min compared with control subjects.
Croatian: Srednja vrijednost AUCtf bila je trostruko veća u ispitanika s klirensom kreatinina između 10 i 30 ml/min nego u kontrolnih ispitanika.
English: Dose reduction in paediatric patients without cardiac disease follows the same guidelines as adult patients without cardiac disease regarding haemoglobin levels (Table 2).
Croatian: Za smanjenje doze u pedijatrijskih bolesnika bez srčane bolesti vrijede iste smjernice utemeljene na vrijednostima hemoglobina kao i za odrasle bolesnike bez srčane bolesti (Tablica 2).
English: The haemolytic anaemia associated with ribavirin therapy may result in deterioration of cardiac function and/or worsening of pre-existing cardiac disease.
Croatian: Hemolitička anemija povezana s terapijom ribavirinom može dovesti do slabljenja funkcije srca i/ili pogoršanja postojeće bolesti srca.
English: For laboratory monitoring of pregnancy, please refer to Laboratory tests.
Croatian: Za laboratorijsko praćenje trudnoće vidjeti odlomak ″Laboratorijski nalazi″.
English: Plasma concentrations achieved in rat pups were below human plasma concentrations at the therapeutic dose.
Croatian: U mladih su štakora koncentracije u plazmi bile ispod koncentracija kakve se nalaze u ljudskoj plazmi pri terapijskim dozama.
English: Ribavirin, by having an inhibitory effect on inosine monophosphate dehydrogenase, may interfere with azathioprine metabolism possibly leading to an accumulation of 6-methylthioinosine monophosphate (6-MTIMP), which has been associated with myelotoxicity in patients treated with azathioprine.
Croatian: Ribavirin svojim inhibicijskim učinkom na inozin monofosfat dehidrogenazu može interferirati s metabolizmom azatioprina, što može dovesti do nakupljanja 6-metiltioinozin monofosfata (6-MTIMP) koje se u bolesnika liječenih azatioprinom povezuje s mijelotoksičnošću.
English: Table 3 provides guidelines for discontinuation based on the patient's indirect bilirubin concentration.
Croatian: U Tablici 3 navode se smjernice za prekid primjene na temelju bolesnikove koncentracije indirektnog bilirubina.
English: Most of the changes in laboratory values in the ribavirin/peginterferon alfa-2b clinical trial were mild or moderate.
Croatian: Promjene u laboratorijskim vrijednostima u kliničkom ispitivanju ribavirina/peginterferona alfa-2b bile su većinom blage ili umjerene.
English: A five-year long-term, observational, follow-up study enrolled 94 paediatric chronic hepatitis C patients after treatment in a multicentre trial.
Croatian: U 5-godišnje dugoročno opservacijsko ispitivanje praćenja uključena su 94 pedijatrijska bolesnika s kroničnim hepatitisom C nakon završetka liječenja u multicentričnom ispitivanju.
English: Ribavirin Teva Pharma B.V. tablets are packaged in aluminium blisters consisting of polyvinyl chloride (PVC)/polyethylene (PE)/polyvinyl Acetate (PVAc)
Croatian: Ribavirin Teva Pharma B.V. tablete su pakirane u aluminijske blistere od polivinilklorid (PVC)/polietilen(PE)/polivinilacetata (PVAc).
English: You or your female partner must use an effective contraceptive during the time you are taking this medicine and for 7 months after stopping treatment.
Croatian: Vi ili Vaša partnerica morate koristiti učinkovitu kontracepciju za vrijeme Vašeg liječenja lijekom Ribavirin Teva Pharma B.V. i tijekom 7 mjeseci nakon prestanka liječenja.
English: Therefore, there is a minimal potential for P450 enzyme-based interactions.
Croatian: Stoga je potencijal razvoja interakcija vezanih uz citokrom P450 minimalan.
English: Film coating, composed of : polyvinyl alcohol - partly hydrolysed, macrogol / polyethylene glycol 3350, titanium dioxide (E171), talc, iron oxide red, iron oxide yellow, iron oxide black.
Croatian: Film ovojnica: poli(vinilni alkohol) - djelomično hidrolizirani; makrogol/polietilenglikol 3350; titanijev dioksid (E171); talk; željezov oksid, crveni; željezov oksid žuti; željezov oksid, crni.
English: Due to substantial increases in ribavirin plasma concentrations in patients with moderate and severe renal impairment, ribavirin dose adjustments are recommended in adult patients with creatinine clearance < 50 mL/minute.
Croatian: Zbog značajnih povećanja koncentracije ribavirina u plazmi, u bolesnika s umjerenim i teškim oštećenjem funkcije bubrega, preporučuje se prilagoditi dozu ribavirina u odraslih bolesnika s klirensom kreatinina <50 ml/min.
English: Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Croatian: Unutar svake skupine učestalosti nuspojave su navedene u padajućem nizu prema ozbiljnosti.
English: Pharmacotherapeutic group: Antivirals for systemic use, nucleosides and nucleotides excl.reverse transcriptase inhibitors, ATC code: J05AB04.
Croatian: Farmakoterapijska skupina: pripravci za liječenje sustavnih virusnih infekcija, nukleozidi i nukleotidi osim inhibitora reverzne transkriptaze, ATK oznaka J05AB04.
English: There are no data for paediatric patients with cardiac disease (see section 4.4).
Croatian: Nema podataka o primjeni u pedijatrijskih bolesnika sa srčanom bolešću (vidjeti dio 4.4).
English: peginterferon alfa-2b (1.5 µg /kg/ week)
Croatian: peginterferon alfa-2b (1,5 µg/kg/ tjedan)
English: The mechanism by which ribavirin in combination with other medicinal products exerts its effects against HCV is unknown.
Croatian: Nije poznat mehanizam putem kojega ribavirin u kombinaciji s drugim lijekovima djeluje na HCV.
English: Patients who are treated with interferon alfa-2b and ribavirin after previous relapse from interferon therapy or who are treated for a shorter period are likely to have an improved safety profile than that described below.
Croatian: U bolesnika koji se liječe interferonom alfa-2b i ribavirinom zbog relapsa nakon prethodnog liječenja interferonom te u onih koji se liječe kraće vrijeme veća je vjerojatnost da će imati bolji sigurnosni profil nego što je opisano u nastavku.
English: Ribavirin Teva Pharma B.V. 400 mg film-coated tablets are light-pink to pink, (debossed with “R” on one side and “400” on the other).
Croatian: Ribavirin Teva Pharma B.V. 400 mg filmom obložene tablete su svijetlo ružičaste do ružičaste (s utisnutim "R" na jednoj strani i "400" na drugoj).
English: In general, the adverse reactions profile in children and adolescents was similar to that observed in adults, although there is a paediatric-specific concern regarding growth inhibition.
Croatian: Profil nuspojava u djece i adolescenata općenito je bio sličan onom zabilježenom u odraslih bolesnika, uz problem specifičan za pedijatrijsku populaciju koji se odnosi na zastoj u rastu.
English: This decline was significant among responders (0.3 for Metavir and -1.2 for Ishak) and stable (-0.1 for Metavir and -0.2 for Ishak) among non-responders.
Croatian: To je smanjenje bilo značajno u bolesnika koji su odgovorili na liječenje (-0,3 za Metavir te -1,2 za Ishak) te stabilno (-0,1 za Metavir te -0,2 za Ishak) u bolesnika bez odgovora.
English: Therefore the use of zidovudine and ribavirin in combination with alpha interferons is not recommended.
Croatian: Stoga se ne preporučuje primjena zidovudina i ribavirina u kombinaciji s alfa interferonima.
English: The exacerbation of anaemia due to ribavirin has been reported when zidovudine is part of the regimen used to treat HIV although the exact mechanism remains to be elucidated.
Croatian: Egzacerbacija anemije uzrokovana ribavirinom prijavljena je kada je u protokol liječenja HIV infekcije bio uključen zidovudin, iako točan mehanizam još treba razjasniti.
English: Although haematological toxicities of neutropenia, thrombocytopenia and anaemia occurred more frequently in HCV/HIV co-infected patients, the majority could be managed by dose modification and rarely required premature discontinuation of treatment (see section 4.4).
Croatian: Premda su se hematološki toksični učinci poput neutropenije, trombocitopenije i anemije javljali češće u bolesnika s istodobnom infekcijom HCV-om i HIV-om, većina ih se mogla zbrinuti prilagodbom doze, a rijetko je trebalo ranije obustaviti liječenje (vidjeti dio 4.4).
English: Ribavirin may be used in combination with interferon alfa-2b (see section 4.4).
Croatian: Ribavirin se može primjenjivati u kombinaciji s interferonom alfa-2b (vidjeti dio 4.4).