FrancophonIA/ELRC3.0 huggingface dataset:
English: AUC: ↑ 34 % (↑ 18 to ↑ 53) Cmax: ↑ 49 % (↑ 32 to ↑ 69) Efavirenz:
Slovenian: Cmax: ↑ 49 % (↑ 32 do ↑ 69) efavirenz:
English: Methadone(a medicine used to treat opiate addiction):your doctor may recommend an alternative treatment.
Slovenian: Metadon (zdravilo za zdravljenje odvisnosti od opiatov):zdravnikvam bo morda svetoval drugo zdravljenje.
English: Norepinephrine and dopamine reuptake inhibitor Bupropion/Efavirenz [150 mg single dose (sustained release)/600 mg once daily]
Slovenian: Zaviralec ponovnega privzema noradrenalina in dopamina bupropion/efavirenz [150 mg enkratni odmerek (podaljšano sproščanje)/600 mg enkrat na dan]
English: Bupropion: AUC: ↓ 55% (↓ 48 to ↓ 62)
Slovenian: bupropion: AUC: ↓ 55 % (↓ 48 do
English: AUC: ↓ 71% (↓ 67 to ↓ 74) Cmax: ↓ 51% (↓ 46 to ↓ 56) Cmin: ↓ 91% (↓ 88 to ↓ 92) Efavirenz:
Slovenian: AUC: ↓ 71 % (↓ 67 do ↓ 74) Cmax: ↓ 51 % (↓ 46 do ↓ 56) Cmin: ↓ 91 % (↓ 88 do ↓ 92) efavirenz:
English: Most cases occurred in patients who already had liver disease, but there have been a few reports in patients without any existing liver disease.
Slovenian: Večina primerov se je pojavila pri bolnikih, ki so že imeli bolezen jeter,
English: The daily dose of rifabutin should be increased by 50 % when administered with efavirenz.
Slovenian: Pri sočasni uporabi z efavirenzem je treba dnevni odmerek rifabutina povečati za 50 %.
English: EU/1/99/111/005 - bottle
Slovenian: EU/1/99/111/005 - plastenka
English: The recommended dose of efavirenz in combination with nucleoside analogue reverse transcriptase inhibitors (NRTIs) with or without a PI (see section 4.5) is 24 ml orally, once daily.
Slovenian: V kombinaciji z nukleozidnimi zaviralci reverzne transkriptaze (NRTI-ji), z ali brez ZP, je priporočeni odmerek efavirenza 24 ml peroralno, enkrat na dan (glejte poglavje 4.5).
English: * When compared to atazanavir 300 mg/ritonavir 100 mg once daily in the evening without efavirenz.
Slovenian: (indukcija CYP3A4) *v primerjavi z atazanavirjem 300 mg/ritonavirjem 100 mg enkrat na dan zvečer brez efavirenza.
English: If you are affected your doctor may suggest that you take Stocrin at bedtime and on an empty stomach.
Slovenian: Če se pojavijo pri vas, vam bo zdravnik morda svetoval, da zdravilo Stocrin jemljete pred spanjem in na tešče.
English: Ethinyloestradiol+Norgestimate/ Efavirenz (0.035 mg+0.25 mg once daily/600 mg once daily)
Slovenian: HORMONSKI KONTRACEPTIVI peroralni: etinilestradiol+norgestimat/efavirenz (0,035 mg+0,25 mg enkrat na dan/ 600 mg enkrat na dan)
English: When your Stocrin supply starts to run low, get more from your doctor or pharmacist.
Slovenian: Ko gre vaša zaloga zdravila Stocrin h koncu, si ga priskrbite pri zdravniku oz. farmacevtu.
English: Dose (mg)*
Slovenian: Stocrin kg odmerek (mg)*
English: STOCRIN is indicated in antiviral combination treatment of human immunodeficiency virus-1 (HIV-1) infected adults, adolescents and children 3 years of age and older.
Slovenian: Zdravilo STOCRIN je indicirano za kombinirano protivirusno zdravljenje odraslih, mladostnikov in otrok, starih tri leta ali več, ki so okuženi z virusom humane imunske pomanjkljivosti tipa 1 (HIV-1).
English: Medium chain triglycerides Benzoic acid (E210) Strawberry/mint flavour
Slovenian: 6.1 Seznam pomožnih snovi srednjeverižni nasičeni trigliceridi benzojska kislina (E210) aroma jagode/mete
English: Grazoprevir: AUC: ↓83% Cmax: ↓87%
Slovenian: AUC: ↓ 83 % Cmax: ↓ 87 %
English: Efavirenz kg
Slovenian: Efavirenz kg odmerek (mg)
English: If you take too much Stocrin contact your doctor or nearest emergency department for advice.
Slovenian: Če ste vzeli večji odmerek zdravila Stocrin, kot bi smeli Če vzamete preveč zdravila Stocrin, se posvetujte z zdravnikom ali obiščite najbližjo urgenco.
English: AUC: ↓ 60 % (↓ 52 to ↓ 68) Cmax: ↓ 62 % (↓ 55 to ↓ 78) (CYP3A4 induction) Co-administration of efavirenz with atorvastatin, pravastatin, or simvastatin did not affect efavirenz AUC or Cmax values.
Slovenian: Cmax: ↓ 62 % (↓ 55 do ↓ 78) (indukcija CYP3A4) Sočasna uporaba efavirenza atorvastatinom, pravastatinom ali simvastatinom ni vplivala na vrednosti AUC ali Cmax efavirenza.
English: Always take this medicine exactly as your doctor or pharmacisthas toldyou.
Slovenian: Pri jemanju tega zdravila natančno upoštevajte navodila zdravnika ali farmacevta.
English: Outer carton: STOCRIN 50 mg tablets
Slovenian: Škatla: STOCRIN 50 mg tablete
English: Ritonavir: Morning AUC: ↑ 18 % (↑ 6 to
Slovenian: AUC zjutraj: ↑ 18 % (↑ 6 do ↑ 33)
English: A similar reduction in indinavir exposures was observed when indinavir 1,000 mg q8h was given with efavirenz 600 mg daily.
Slovenian: Pri jemanju indinavirja 1.000 mg q8h z efavirenzem 600 mg na dan so opazili podobno zmanjšanje izpostavljenosti indinavirju.
English: 180 ml oral solution Oral syringe with a pushin bottleneck adapter.
Slovenian: 180 ml peroralne raztopine brizga za peroralno uporabo z nastavkom, ki se pritisne v vrat plastenke
English: Your doctor may consider giving you an alternative medicine or changing the dose of the proteaseinhibitors.
Slovenian: Zdravnik vam bo po potrebi lahko predpisal drugo zdravilo ali spremenil odmerek zaviralcev proteaze.
English: Wipe the adapter and replace the cap tightly over it.
Slovenian: Nastavek obrišite in nanj tesno namestite zamašek.
English: The response rate, based on the NC = F analysis of the percentage of patients with plasma HIV-RNA < 400 copies/ml at 48 weeks was 60 % (95 %, C.I.
Slovenian: Delež bolnikov, ki so se odzvali na zdravljenje, je bil glede na NK = NA analizo odstotkov bolnikov s plazemsko HIV-RNA < 400 kopij/ml po 48 tednih 60 % (95-odstotni IZ 47, 72) ter 53 % (IZ 40, 66) glede na odstotek bolnikov s plazemsko HIV-RNA < 50 kopij/ml.
English: • Each ml of Stocrin oral solution contains 30 mg of the active substance efavirenz.
Slovenian: • En ml peroralne raztopine Stocrin vsebuje 30 mg učinkovine efavirenza.
English: ACID REDUCING AGENTS Aluminium hydroxide-magnesium hydroxide-simethicone antacid/Efavirenz (30 mL single dose/400 mg single dose)
Slovenian: aluminijev hidroksidni-magnezijev hidroksidni-simetikonijev antacid/efavirenz (enkratni odmerek 30 ml/enkratni odmerek 400 mg) famotidin/efavirenz (enkratni odmerek 40 mg/enkratni odmerek 400 mg)
English: In 35 patients receiving efavirenz 600 mg once daily, steady state Cmax was 12.9 ± 3.7 M (29 %) [mean ± S.D. (% C.V.)], steady state Cmin was 5.6 ± 3.2 M (57 %), and AUC was 184 ± 73 M·h (40 %).
Slovenian: Pri 35 bolnikih, ki so dobivali 600 mg efavirenza enkrat na dan, so bile v stanju dinamičnega ravnovesja Cmax 12,9 ± 3,7 M (29 %) [povprečje ± S.D. (% C.V.)]
English: Co-administration of glecaprevir/pibrentasvir with efavirenz is not recommended.
Slovenian: Sočasne uporabe efavirenza in glekaprevira/pibrentasvira ne priporočamo.
English: Stocrin 50 mg film-coated tablets are supplied in bottles of 30 tablets.
Slovenian: Stocrin 50 mg filmsko obložene tablete so na voljo v plastenkah s 30 tabletami.
English: Convulsions have been observed in patients receiving efavirenz, generally in the presence of known medical history of seizures.
Slovenian: Pri bolnikih, ki se zdravijo z efavirenzem, so opazili krče, običajno pri tistih bolnikih z anamnezo napadov krčev.
English: Therefore, the dosage recommendation provided in Table 1 incorporates a higher dose of efavirenz oral solution for these younger children.
Slovenian: Zaradi tega odmerni režim peroralne raztopine efavirenza za mlajše otroke, ki je podan v preglednici 1, vključuje višje odmerke.
English: Stocrin oral solution (30 mg/ml)
Slovenian: Stocrin peroralna raztopina (30 mg/ml)
English: Telaprevir/Efavirenz (1,125 mg q8h/600 mg once daily)
Slovenian: telaprevir/efavirenz (1,125 mg q8h/600 mg enkrat na dan)
English: Pregnancies have occurred in women taking Stocrin while using a contraceptive implant, although it has not been established that the Stocrin therapy caused the contraceptive to fail.
Slovenian: Nekatere ženske, ki so med uporabo kontracepcijskega vsadka jemale zdravilo Stocrin, so zanosile, kljub temu da ni bilo dokazano, da zdravljenje z zdravilom Stocrin prepreči delovanje kontraceptiva.
English: Outer carton: STOCRIN 200 mg tablets
Slovenian: Škatla: STOCRIN 200 mg tablete
English: Women should not get pregnant during treatment with Stocrin and for 12 weeks thereafter.
Slovenian: Ženske med jemanjem in 12 tednov po prenehanju jemanja zdravila Stocrin ne smejo zanositi.
English: Efavirenz oral solution (30 mg/ml)
Slovenian: Efavirenz peroralna raztopina (30 mg/ml)
English: Bupropion (a medicine used to treat depression or to helpyou stop smoking): your doctor may need to change your dose of bupropion.
Slovenian: Bupropion(zdravilo za zdravljenje depresije ali za pomoč pri prenehanju kajenja): zdravnik vam bo morda spremenil odmerek bupropiona.
English: An oral syringe with a push-in bottle-neck adapter is included in the carton.
Slovenian: V škatli je brizga za peroralno dajanje z nastavkom, ki se pritisne v vrat plastenke.
English: Consider alternatives to efavirenz for co-administration with a drug with a known risk of Torsade de Pointes or when to be administered to patients at higher risk of Torsade de Pointes.
Slovenian: Pri sočasni uporabi z zdravilom, ki ima znano tveganje za torsade de pointes, ali pri uporabi pri bolnikih z večjim tveganjem za torsade de pointes, je treba razmisliti o alternativah efavirenzu.
English: AUC: ↓ 38 % (↓ 28 to ↓ 47) Cmax: ↓ 32 % (↓ 15 to ↓ 46) Cmin: ↓ 45 % (↓ 31 to ↓ 56) Efavirenz:
Slovenian: AUC: ↓ 38 % (↓ 28 do↓ 47) Cmax: ↓ 32 % (↓ 15 do ↓ 46) Cmin: ↓ 45 % (↓ 31 do ↓ 56) efavirenz:
English: Stocrin 600 mg film-coated tablets are supplied in bottles of 30 tablets.
Slovenian: Stocrin 600 mg filmsko obložene tablete so na voljo v plastenkah s 30 tabletami.
English: Stocrincan reduce the amount of statins in your blood.
Slovenian: Zdravilo Stocrinlahko zmanjša količino statinov v krvi.
English: AUC: ↔*/** (↓ 10 to ↑ 26) Cmax: ↔*/** (↓ 5 to ↑ 26) Cmin: ↑ 12 %*/** (↓ 16 to ↑ 49) (CYP3A4 induction).
Slovenian: Cmax: ↔*/** (↓ 5 do ↑ 26) Cmin : ↑ 12 %*/** (↓ 16 do
English: Dose adjustments of atorvastatin may be required (refer to the Summary of Product Characteristics for the atorvastatin).
Slovenian: Morda je treba prilagoditi odmerek atorvastatina (glejte Povzetek glavnih značilnosti zdravila za atorvastatin).
English: Stocrin 200 mg film-coated tablets are supplied in bottles of 90.
Slovenian: Stocrin 200 mg filmsko obložene tablete so na voljo v plastenkah z 90 tabletami.
English: Bupropion (a medicine used to treat depression or to help you stop smoking): your doctor may need to change your dose of bupropion.
Slovenian: Bupropion(zdravilo zazdravljenje depresije ali za pomoč pri prenehanju kajenja): zdravnik vam bo morda spremenil odmerek bupropiona.
English: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil with sofosbuvir/velpatasvir has been shown to significantly decrease plasma concentrations of velpatasvir due to CYP3A induction by efavirenz, which may result in loss of therapeutic effect of velpatasvir.
Slovenian: Sočasna uporaba efavirenza/emtricitabina/dizoproksiltenofoviratas sofosbuvirjem/velpatasvirjem je pokazala pomembno znižanje plazemskih koncentracij velpatasvirja zaradi indukcije CYP3A4 z efavirenzom, kar lahko vodi do izgube terapevtskega učinka velpatasvirja.
English: The bottle adapter, which is already fixed to the nozzle of the syringe, can then be fitted into the neck of the bottle and pressed firmly down.
Slovenian: Nastavek za plastenko s pritrjeno brizgo za peroralno dajanje namestite na vrat plastenke in pritisnite.
English: Dose adjustments of simvastatin may be required (refer to the Summary of Product Characteristics for simvastatin).
Slovenian: Morda je treba prilagoditi odmerek simvastatina (glejte Povzetek glavnih značilnosti zdravila za simvastatin).
English: How to store Stocrin
Slovenian: Shranjevanje zdravila Stocrin
English: AUC: ↓ 26 % (↓ 15 to ↓ 36) Cmax: ↓ 20 % (↓ 11 to ↓ 28) Cmin: ↓ 32 % (↓ 15 to ↓ 46) (CYP3A4 and CYP2B6 induction)
Slovenian: Cmax: ↓ 20 % (↓ 11 do ↓ 28) Cmin: ↓ 32 % (↓ 15 do ↓ 46) (indukcija CYP3A4 in CYP2B6)
English: Integrase strand transfer inhibitor Raltegravir/Efavirenz (400 mg single dose/ - )
Slovenian: Priporočilo glede sočasne uporabe z efavirenzem raltegravir/efavirenz (400 mg enkratni odmerek/ - )
English: AUC: ↓ 35 % (↓ 13 to ↓ 40) Cmax: ↓ 13 % (↓ 0 to ↓ 23) 4-hydroxy atorvastatin:
Slovenian: Cmax: ↓ 13 % (↓ 0 do ↓ 23) 4-hidroksiatorvastatin:
English: AUC12: ↓ 45 % (↓ 38 to ↓ 51) Cmax: ↓ 51 % (↓ 37 to ↓ 62) Efavirenz concentrations not measured, no effect is expected.
Slovenian: Cmax: ↓ 51 % (↓ 37 do ↓ 62) Koncentracij efavirenza niso izmerili.
English: Atovaquone: AUC: ↓ 75% (↓ 62 to ↓ 84)
Slovenian: atovakon: AUC: ↓ 75 % (↓ 62 do
English: AUC: ↓ 18% (↓ 8 to ↓ 27) Cmax: ↓ 14% (↓ 3 to ↓ 24)
Slovenian: AUC: ↓ 18 % (↓ 8 do ↓ 27) Cmax: ↓ 14 % (↓ 3 do ↓ 24) Cmin: ↓ 25 % (↓ 14 do ↓
English: Lopinavir/ritonavir tablets/ Efavirenz
Slovenian: lopinavir/ritonavir mehke kapsule ali peroralna raztopina/efavirenz lopinavir/ritonavir tablete/efavirenz
English: To do this, remove the child-resistant cap and the foil seal.
Slovenian: Najprej odstranite za otroke varen zamašek in zaščitno folijo.
English: AUC: ↓ 39 % (↓ 21 to ↓ 53) Cmax: ↓ 37 % (↓ 20 to ↓ 51) Cmin: ↓ 44 % (↓ 27 to ↓ 58) (decrease in itraconazole concentrations: CYP3A4 induction)
Slovenian: Cmax: ↓ 37 % (↓ 20 do ↓ 51) Cmin: ↓ 44 % (↓ 27 do ↓ 58) (zmanjšanje koncentracij itrakonazola: indukcija CYP3A4) hidroksiitrakonazol:
English: Common (affects 1 to 10 users in 100) - abnormal dreams, difficulty concentrating, dizziness, headache, difficulty sleeping, drowsiness,
Slovenian: Pogosti (pojavijo se pri 1 do 10 od 100 bolnikov) - nenormalne sanje, težave s koncentracijo, omotica, glavobol, oteženo spanje, zaspanost, težave s koordinacijo ali z ravnotežjem - bolečine v trebuhu, driska, slabost (siljenje na bruhanje), bruhanje - srbenje - utrujenost - občutek tesnobe, depresivno počutje
English: Stocrin contains efavirenz and may cause dizziness,impaired concentration, and drowsiness.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Zdravilo Stocrin vsebuje efavirenz in lahko povzroči omotico, motnje koncentracije in zaspanost.
English: Evening Cmax: ↔ Morning Cmin: ↑ 42 % (↑ 9 to b
Slovenian: AUC zvečer: ↔ Cmax zjutraj: ↑ 24 % (↑ 12 do ↑ 38) Cmax zvečer: ↔ Cmin zjutraj: ↑ 42 % (↑ 9 do ↑ 86)
English: Severe rash occurred in less than 1 % of patients treated with efavirenz, and 1.7 % discontinued therapy because of rash.
Slovenian: Hud izpuščaj se je pojavil pri manj kot 1 % bolnikov, zdravljenih z efavirenzem.
English: STOCRIN 50 mg film-coated tablets Each film-coated tablet contains 50 mg of efavirenz.
Slovenian: STOCRIN 50 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 50 mg efavirenza.
English: Ear and labyrinth disorders uncommon tinnitus
Slovenian: Ušesne bolezni, vključno z motnjami labirinta občasni tinitus
English: AUC: ↓ 36 % (↓ 32 to ↓ 40) Cmax: ↓ 21 % (↓ 15 to ↓ 26) Cmin: ↓ 47 % (↓ 41 to ↓ 53) (decrease in carbamazepine concentrations: CYP3A4 induction; decrease in efavirenz concentrations: CYP3A4 and CYP2B6 induction) The steady-state AUC, Cmax and Cmin of the active carbamazepine epoxide metabolite remained unchanged.
Slovenian: Cmax: ↓ 21 % (↓ 15 do ↓ 26) Cmin: ↓ 47 % (↓ 41 do ↓ 53) (zmanjšanje koncentracij karbamazepina: indukcija CYP3A4; zmanjšanje koncentracij efavirenza: indukcija CYP3A4 in CYP2B6)
English: STOCRIN 50 mg film-coated tablets
Slovenian: STOCRIN 50 mg filmsko obložene tablete
English: STOCRIN 200 mg film-coated tablets Each film-coated tablet contains 200 mg of efavirenz.
Slovenian: STOCRIN 200 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 200 mg efavirenza.
English: STOCRIN 30 mg/ml oral solution efavirenz
Slovenian: Stocrin 30 mg/ml peroralna raztopina efavirenz
English: Stocrin 30 mg/ml oral solution efavirenz
Slovenian: STOCRIN 30 mg/ml peroralna raztopina efavirenz
English: STOCRIN 200 mg film-coated tablets
Slovenian: STOCRIN 200 mg filmsko obložene tablete
English: STOCRIN 600 mg film-coated tablets
Slovenian: STOCRIN 600 mg filmsko obložene tablete
English: Pregnancies have occurred in women takingStocrinwhile using a contraceptive implant, although it has not been established that the Stocrin therapy caused the contraceptive to fail.
Slovenian: Nekatere ženske, ki so meduporabo kontracepcijskega vsadka jemale zdravilo Stocrin, so zanosile, kljub temu da ni bilo dokazano, da zdravljenje z zdravilom Stocrin prepreči delovanje kontraceptiva.
English: Efavirenz has not been evaluated in children below 3 years of age or who weigh less than 13 kg.
Slovenian: Pri otrocih mlajših od 3 let ali lažjih od 13 kg uporabe efavirenza niso preučili.
English: AUC: ↓ 75 % (↓ 59 to ↓ 84) Cmax: ↓ 64 % (↓ 57 to ↓ 69) Cmin: ↓ 62 % (↓ 44 to ↓ 75) N-monodesmethyl diltiazem: AUC: ↓ 37 % (↓ 17 to ↓ 52) Cmax: ↓ 28 % (↓ 7 to ↓ 44) Cmin: ↓ 37 % (↓ 17 to ↓ 52) Efavirenz:
Slovenian: Cmax: ↓ 64 % (↓ 57 do ↓ 69) Cmin: ↓ 62 % (↓ 44 do ↓ 75) N-monodesmetil-diltiazem: AUC: ↓ 37 % (↓ 17 do ↓
English: Ritonavir/Efavirenz (500 mg twice daily/600 mg once daily)
Slovenian: ritonavir/efavirenz (500 mg dvakrat na dan/600 mg enkrat na dan)
English: AUC: ↓ 69 % (↓ 55 to ↓ 79) Cmax: ↓ 60 % (↓ 50 to ↓ 68) Cmin: ↓ 63 % (↓ 44 to ↓ 75) Desacetyl diltiazem:
Slovenian: Cmax: ↓ 60 % (↓ 50 do ↓ 68) Cmin: ↓ 63 % (↓ 44 do ↓ 75) desacetildiltiazem:
English: STOCRIN 600 mg film-coated tablets Each film-coated tablet contains 600 mg of efavirenz.
Slovenian: STOCRIN 600 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 600 mg efavirenza.
English: • Each Stocrin film-coated tablet contains 50 mg of the active substance efavirenz.
Slovenian: • Ena filmsko obložena tableta Stocrin vsebuje 50 mg učinkovine efavirenza.
English: AUC: ↓ 43 % (↓ 34 to ↓ 50) Cmax: ↓ 12 % (↓ 1 to ↓ 26) 2-hydroxy atorvastatin:
Slovenian: Cmax: ↓ 12 % (↓ 1 do ↓ 26) 2-hidroksiatorvastatin:
English: 3, or in PI or NNRTI-experienced patients.
Slovenian: 3, ali bolnikih, ki so se že zdravili z zaviralcem proteaze ali NNRTI.
English: AUC: ↓ 27 % (↓ 20 to ↓ 33) Cmax: ↓ 20 % (↓ 15 to ↓ 24) Cmin: ↓ 35 % (↓ 24 to ↓ 44) Efavirenz:
Slovenian: Cmax: ↓ 20 % (↓ 15 do ↓ 24) Cmin: ↓ 35 % (↓ 24 do ↓ 44) efavirenz:
English: The pharmacokinetics of efavirenz have not been studied in patients with renal insufficiency; however, less than 1 % of an efavirenz dose is excreted unchanged in the urine, so the impact of renal impairment on efavirenz elimination should be minimal (see section 4.2).
Slovenian: Pri bolnikih z ledvično insuficienco niso preučevali farmakokinetike efavirenza, vendar se manj kot 1 % odmerka efavirenza izloči nespremenjenega z urinom.
English: For this reason, efavirenz oral solution should not be given to children less than 3 years of age.
Slovenian: Zaradi tega uporabe peroralne raztopine efavirenza pri otrocih, mlajših od 3 let, ne priporočamo.
English: • Each Stocrin film-coated tablet contains 600 mg of the active substance efavirenz.
Slovenian: • Ena filmsko obložena tableta Stocrin vsebuje 600 mg učinkovine efavirenza.
English: Pharmacotherapeutic group: Antivirals for systemic use.
Slovenian: Farmakoterapevtska skupina: Zdravila za sistemsko zdravljenje virusnih infekcij, nenukleozidni zaviralci reverzne transkriptaze.
English: Skin rash was considered treatment related in 18 % of patients treated with efavirenz.
Slovenian: Pri 18 % bolnikov, zdravljenih z efavirenzem, so menili, da je pojav izpuščaja povezan z zdravljenjem.
English: Dose adjustments of pravastatin may be required (refer to the Summary of Product Characteristics for pravastatin).
Slovenian: Morda je treba prilagoditi odmerek pravastatina (glejte Povzetek glavnih značilnosti zdravila za pravastatin).
English: • Each Stocrin film-coated tablet contains 200 mg of the active substance efavirenz.
Slovenian: • Ena filmsko obložena tableta Stocrin vsebuje 200 mg učinkovine efavirenza.
English: ANTI-INFECTIVES HIV antivirals
Slovenian: ZDRAVILA ZA KISLINSKO POGOJENE BOLEZNI
English: Proguanil: AUC: ↓ 43% (↓ 7 to ↓ 65)
Slovenian: atorvastatin: AUC: ↓ 43 % (↓ 34 do ↓
English: AUC: ↓ 64 % (↓ 62 to ↓ 67) Cmax: ↓ 46 % (↓ 39 to ↓ 52) Cmin: ↓ 82 % (↓ 79 to ↓ 85) Levonorgestrel
Slovenian: Cmax: ↓ 46 % (↓ 39 do ↓ 52) Cmin: ↓ 82 % (↓ 79 do ↓ 85) levonorgestrel (aktivni presnovek):
English: ‡, disturbance in attention (3.6 %), dizziness (8.5 %), headache (5.7 %), somnolence uncommon agitation, amnesia, ataxia, coordination abnormal, convulsions, thinking abnormal, tremor
Slovenian: Bolezni živčevja pogosti motnje cerebelarne koordinacije in ravnotežja motnje koncentracije (3,6 %), omotica (8,5 %), glavobol (5,7 %), zaspanost (2,0 %)*
English: AUC: ↓ 39 % (↓ 27 to ↓ 50) Cmax: ↓ 29 % (↓ 15 to ↓ 40) Cmin: ↓ 46 % (↓ 31 to ↓ 58) Efavirenz:
Slovenian: Cmax: ↓ 29 % (↓ 15 do ↓ 40) Cmin: ↓ 46 % (↓ 31 do ↓ 58) efavirenz:
English: Maraviroc:
Slovenian: maravirok.
English: AUC: ↓ 58 % (↓ 39 to ↓ 68) Cmax: ↓ 51 % (↓ 32 to ↓ 58) Total active HMG Co-A reductase inhibitors:
Slovenian: Cmax: ↓ 51 % (↓ 32 do ↓ 58) skupni aktivni zaviralci HMG
English: Evening Cmin: ↑ 24 % (↑ 3 to
Slovenian: Cmin zvečer: ↑ 24 % (↑ 3 do efavirenz: AUC: ↑ 21 % (↑ 10 do ↑
English: AUC: ↓ 37 % (↓ 14 to ↓ 55) Cmax: ↓ 35 % (↓ 12 to ↓ 52) Cmin: ↓ 43 % (↓ 18 to ↓ 60) Efavirenz:
Slovenian: Cmax: ↓ 35 % (↓ 12 do ↓ 52) Cmin: ↓ 43 % (↓ 18 do ↓ 60) efavirenz:
English: Darunavir:
Slovenian: ritonavir:
English: STOCRIN 50 mg film-coated tablets efavirenz
Slovenian: Stocrin 50 mg filmsko obložene tablete efavirenz
English: Stocrin 50 mg film-coated tablets efavirenz
Slovenian: STOCRIN 50 mg filmsko obložene tablete efavirenz
English: (22 - 42 % lower) and a shorter terminal half-life compared with single dose administration (see below).
Slovenian: Pri neokuženih prostovoljcih so 10-dnevni večkratni odmerki 200 - 400 mg na dan povzročili manjšo akumulacijo zdravila od pričakovane (22 - 42 % manjšo) in krajši končni razpolovni čas v primerjavi z enkratnim odmerkom (glejte spodaj).
English: Stocrin can reduce the amount of statins in your blood.
Slovenian: ZdraviloStocrinlahko zmanjša količino statinov v krvi.
English: AUC: ↓ 18% (↓ 10 to ↓ 26) Cmax: ↓ 24% (↓ 15 to ↓ 32)
Slovenian: Cmax : ↓ 17 % (↓ 6 do ↓ 26) Cmin : ↓ 50 % (↓ 40 do ↓
English: Stocrin 600 mg film-coated tablets efavirenz
Slovenian: STOCRIN 600 mg filmsko obložene tablete efavirenz
English: Ginkgo bilobaextracts(herbal preparation)
Slovenian: Izvlečke ginka (pripravekrastlinskega izvora).
English: Cmin: ↓ 10% (↑ 1 to ↓ 19)%
Slovenian: Cmax: ↑ 23 % (↓ 1 do ↑ 53)
English: AUC: ↓ 40 % (↓ 26 to ↓ 57) Cmax: ↓ 18 % (↓ 59 to ↑ 12)
Slovenian: Cmax: ↓ 18 % (↓ 59 do ↑ 12)
English: Stocrin 200 mg film-coated tablets efavirenz
Slovenian: STOCRIN 200 mg filmsko obložene tablete efavirenz
English: STOCRIN 200 mg film-coated tablets efavirenz
Slovenian: Stocrin 200 mg filmsko obložene tablete efavirenz
English: • With the bottle upright, fit the tip of the syringe into the bottle adapter.
Slovenian: • Plastenko držite v pokončnem položaju in namestite konico brizge na nastavek.
English: 3 and the mean baseline HIV-RNA level was 60,250 copies/ml.
Slovenian: 60.250 kopij/ml.
English: • Stocrin is for oral use.
Slovenian: • Zdravilo Stocrin se vzame skozi usta.
English: Cmax: ↓ 34% (↓ 21 to ↓ 47)
Slovenian: AUC: ↓ 34 % (↓ 21 do ↓
English: AUC: ↓ 39 % (↓ 30 to ↓ 46) Cmax: ↓ 26 % (↓ 15 to ↓ 35) Clarithromycin
Slovenian: AUC: ↓ 43 % (↓ 7 do ↓ 65) Cmax: ↔
English: You should consult your doctor if you have a rash, since some rashes may be serious; however, most cases of rash disappear without any change to your treatment with Stocrin.
Slovenian: V primeru izpuščaja se posvetujte z zdravnikom, ker so nekateri izpuščaji lahko resni.
English: AUC: ↓ 69 % (↓ 62 to ↓ 73) Cmax: ↓ 76 % (↓ 63 to ↓ 79) Simvastatin acid:
Slovenian: Cmax: ↓ 76 % (↓ 63 do ↓ 79) simvastatin v obliki kisline: AUC: ↓ 58 % (↓ 39 do ↓
English: STOCRIN 30 mg/ml oral solution
Slovenian: STOCRIN 30 mg/ml peroralna raztopina
English: Each film-coated tablet contains: efavirenz 200 mg
Slovenian: Ena filmsko obložena tableta vsebuje 200 mg efavirenza.
English: It's important to follow these instructions carefully.
Slovenian: Zelo pomembno je, da natančno upoštevate ta navodila.
English: General advice:
Slovenian: Splošni nasveti: