FrancophonIA/ELRC3.0 huggingface dataset:
English: Rebif solution for subcutaneous injection in a cartridge is intended for multidose use with either the RebiSmart electronic injection device or the RebiSlide manual pen-injector device following adequate training of the patient and/or carer.
Slovenian: Zdravilo Rebif raztopina za subkutano injiciranje v vložku je namenjeno za večkratno odmerjanje, bodisi z elektronskim pripomočkom za injiciranje RebiSmart ali z ročnim injekcijskim peresnikom RebiSlide, po ustreznem izobraževanju bolnika in/ali negovalca.
English: Rebif, like other interferons beta, has a potential for causing severe liver injury including acute hepatic failure (see section 4.8).
Slovenian: Zdravilo Rebif ima, tako kot drugi interferoni beta, potencial za povzročanje hudih jetrnih poškodb, vključno z akutno jetrno odpovedjo (glejte poglavje 4.8).
English: In healthy volunteers after intravenous administration, interferon beta-1a exhibits a sharp multi-exponential decline, with serum levels proportional to the dose.
Slovenian: Pri zdravih prostovoljcih se po intravenskem dajanju interferona beta-1a pokaže oster multieksponentni padec serumskih vrednosti, sorazmerno z odmerkom.
English: Other forms of multiple sclerosis
Slovenian: Druge oblike multiple skleroze
English: Rebif is indicated for the treatment of
Slovenian: Zdravilo Rebif je indicirano za zdravljenje
English: • a dry cotton ball or gauze
Slovenian: • suh kos bombažne vate ali gaze
English: When first starting treatment with Rebif, the dose should be gradually escalated in order to allow tachyphylaxis to develop thus reducing adverse reactions.
Slovenian: Na začetku prvega zdravljenja z zdravilom Rebif se odmerek postopno viša z namenom razvoja tahifilaksije in s tem zmanjšanja neželenih učinkov.
English: Rebif solution is clear to opalescent.
Slovenian: Raztopina Rebif je bistra do opalescentna.
English: • Keep track of and rotate your injection sites, so that one area is not injected too often.
Slovenian: • Beležite si mesta injiciranja in jih izmenjujte tako, da ne zabadate prepogosto v eno in isto mesto.
English: Thrombotic microangiopathy including thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome* (class label for interferon beta products, see section 4.4), pancytopenia*
Slovenian: trombotična mikroangiopatija, vključno s trombotično trombocitopenično purpuro/hemolitično-uremičnim sindromom * (označevanje razreda zdravil, ki vsebujejo interferon beta; glejte poglavje 4.4), pancitopenija*
English: Patients were randomised in a double-blind manner to either Rebif 44 micrograms given three times per week, Rebif 44 micrograms once weekly, or placebo.
Slovenian: Bolniki so bili randomizirani na dvojno slep način v bodisi skupino, ki je prejemala zdravilo Rebif 44 mikrogramov trikrat na teden, v skupino, ki je prejemala zdravilo Rebif 44 mikrogramov enkrat na teden, ali v skupino, ki je prejemala placebo.
English: Severe elevations in transaminases
Slovenian: močno zvišanje ravni transaminaz
English: Patients being treated with Rebif may occasionally develop new or worsening thyroid abnormalities.
Slovenian: Pri bolnikih, ki se zdravijo z zdravilom Rebif, se lahko občasno razvijejo ali pa poslabšajo motnje delovanja ščitnice.
English: • Read all the following instructions carefully before using RebiDose.
Slovenian: • Pred uporabo peresnika RebiDose natančno preberite naslednja navodila.
English: The proportion of patients with disability progression, as defined by at least one point increase in EDSS confirmed three months later, was reduced from 39% (placebo) to 30% (Rebif 22 micrograms).
Slovenian: Odstotek bolnikov z napredovanjem nesposobnosti, definiranim kot povečanje za najmanj eno točko po EDSS, potrjenim po 3 mesecih, se je zmanjšal iz 39 % (placebo) na 30 % (zdravilo Rebif 22 mikrogramov).
English: • Hold RebiSlide firmly and slide the release button which is on the side of the device.
Slovenian: • Trdno držite pripomoček RebiSlide in potisnite sprožilni gumb, ki je ob strani pripomočka.
English: Regardless of the route of dosing, pronounced pharmacodynamic changes are associated with the administration of Rebif.
Slovenian: Neodvisno od poti odmerjanja so z uporabo zdravila Rebif povezane izrazite farmakodinamične spremembe.
English: If the patient experiences any break in the skin, which may be associated with swelling or drainage of fluid from the injection site, the patient should be advised to consult with their physician before continuing injections with Rebif.
Slovenian: Bolniku moramo svetovati, da se v primeru pojava kakršne koli razpoke v koži, ki jo lahko spremlja oteklina ali odtekanje tekočine iz mesta injiciranja, posvetuje s svojim zdravnikom, preden nadaljuje z uporabo injekcij zdravila Rebif.
English: Injection site cellulitis*
Slovenian: celulitis na mestu injiciranja*
English: Before the injection
Slovenian: Pred injiciranjem
English: Store in a refrigerator (2°C - 8°C) away from the cooling element.
Slovenian: Shranjujte v hladilniku (2 ºC-8 ºC), stran od zamrzovalnega predela.
English: If you stop using Rebif
Slovenian: Če ste prenehali uporabljati zdravilo Rebif
English: Frequency not known: Transient neurological symptoms (i.e. hypoesthesia, muscle spasm, paraesthesia, difficulty in walking, musculoskeletal stiffness) that may mimic multiple sclerosis exacerbations*
Slovenian: prehodni nevrološki simptomi (npr. hipoestezija, mišični krči, parestezije, težave pri hoji in mišično-skeletna okorelost), ki so lahko podobni poslabšanju multiple skleroze*
English: It may cause toxic reactions and anaphylactoid reactions in infants and children up to 3 years old.
Slovenian: Lahko povzroči toksične reakcije in anafilaktoidne reakcije pri dojenčkih in otrocih do 3 leta starosti.
English: • The active substance is interferon beta-1a.
Slovenian: • Učinkovina je interferon beta-1a.
English: What Rebif looks like and contents of the pack
Slovenian: Izgled zdravila Rebif in vsebina pakiranja
English: Frequency not known: Pulmonary arterial hypertension* (class label for interferon products, see below Pulmonary arterial hypertension)
Slovenian: pljučna arterijska hipertenzija* (velja za skupino zdravil, ki vsebujejo interferone - glejte Pljučna arterijska hipertenzija spodaj)
English: If a patient responds poorly to therapy with Rebif, and has neutralising antibodies, the treating physician should reassess the benefit/risk ratio of continued Rebif therapy.
Slovenian: Pri bolnikih, kjer je odziv na zdravljenje z zdravilom Rebif slab in so razvili protitelesa, mora lečeči zdravnik ponovno pretehtati razmerje koristi in tveganja pri nadaljevanju zdravljenja z zdravilom Rebif.
English: • Blood clots in the small blood vessels may occur during your treatment.
Slovenian: • Med zdravljenjem se lahko pojavijo krvni strdki v majhnih krvnih žilah.
English: Peaks of similar height and time were observed for most of these markers after first and sixth administration.
Slovenian: Za večino teh označevalcev so po prvem in šestem dajanju zdravila opazili podobne najvišje vrednosti, ki so se pojavile približno ob istem času.
English: Primary progressive multiple sclerosis
Slovenian: Primarna progresivna multipla skleroza
English: Symptoms may include increased bruising, bleeding, fever, extreme weakness, headache, dizziness or light-headedness.
Slovenian: Simptomi lahko vključujejo povečano nastajanje modric, krvavitve, povišano telesno temperaturo, izjemno šibkost, glavobol, omotico ali vrtoglavico.
English: This might happen several weeks to several years after starting Rebif.
Slovenian: To se lahko pojavi nekaj tednov do nekaj let po začetku zdravljenja z zdravilom Rebif.
English: • thyroid,
Slovenian: • ledvic,
English: If you forget to use Rebif
Slovenian: Če ste pozabili uporabiti zdravilo Rebif
English: Injection site necrosis, injection site mass, injection site abscess, injection site infections*, increased sweating*
Slovenian: nekroza na mestu injiciranja, bula na mestu injiciranja, absces na mestu injiciranja, okužbe na mestu injiciranja*, povečano potenje*
English: If you experience troubling local reactions, contact your doctor.
Slovenian: Če se pojavijo moteče lokalne reakcije, se posvetujte z zdravnikom.
English: The safety guard automatically surrounds the needle and locks into place to protect you from the needle.
Slovenian: Varovalo se samodejno povezne čez iglo in jo zaradi zaščite blokira.
English: Weeks 1-2
Slovenian: • 1. in 2. teden
English: OTHER Merck Europe B.V.
Slovenian: DRUGI PODATKI Merck Europe B.V.
English: Asymptomatic transaminase increase
Slovenian: asimptomatsko zvečanje ravni transaminaz
English: Laboratory abnormalities are associated with the use of interferons.
Slovenian: Z uporabo interferonov so povezani nenormalni laboratorijski testi.
English: You should discuss this with your doctor if you are concerned.
Slovenian: Če ste zaskrbljeni, se o tem posvetujte s svojim zdravnikom.
English: • Disorders of the retina (back of the eye) such as inflammation or blood clots with consequent vision disorders (vision disturbances, loss of vision)
Slovenian: • bolezni mrežnice (očesnega ozadja), kot so vnetje ali krvni strdki s posledičnimi motnjami vida
English: Retinal vascular disorders (i.e. retinopathy, cotton wool spots, obstruction of retinal artery or vein)*
Slovenian: bolezni mrežničnega žilja (npr. retinopatija, pojav belih lis na mrežnici in zamašitev mrežnične arterije ali vene)*
English: • Remove and discard the needle according to the instruction manual provided with your device.
Slovenian: • Iglo odstranite in zavrzite v skladu z navodili za uporabo v priročniku, ki je priložen vašemu pripomočku.
English: The recommended posology of Rebif is 44 micrograms given three times per week by subcutaneous injection.
Slovenian: Priporočeno odmerjanje zdravila Rebif je 44 mikrogramov, trikrat na teden v obliki subkutane injekcije.
English: • Your doctor will tell you how to choose the correct dose of 22 micrograms.
Slovenian: • Kako izbrati pravilen odmerek 22 mikrogramov vam bo razložil vaš zdravnik.
English: To help reduce these symptoms your doctor may advise you to take a fever reducing painkiller before a dose of Rebif and then for 24 hours after each injection.
Slovenian: Za zmanjšanje navedenih simptomov, vam zdravnik lahko svetuje, da pred odmerkom zdravila Rebif in nato še naslednjih 24 ur po vsaki injekciji vzamete zdravilo, ki deluje proti zvišani telesni temperaturi in bolečinam.
English: • Rebif is given by injection under the skin (subcutaneously) using a pre-filled pen called “RebiDose”.
Slovenian: • Zdravilo Rebif se daje z injiciranjem pod kožo (subkutano), z uporabo napolnjenega injekcijskega peresnika, ki se imenuje »RebiDose«.
English: Rebif (interferon beta-1a) shares the same amino acid sequence with endogenous human interferon beta.
Slovenian: Zdravilo Rebif (interferon beta-1a) ima enako zaporedje aminokislin kot endogeni človeški interferon beta.
English: If you experience any of these symptoms, contact your doctor for advice.
Slovenian: Če opazite katerega koli od teh simptomov, se takoj posvetujte s svojim zdravnikom.
English: INFORMATION IN BRAILLE rebif 8.8/0.1 / 22/0.25
Slovenian: PODATKI V BRAILLOVI PISAVI rebif 8,8/0,1 / 22/0,25
English: Warnings and precautions Talk to your doctor, pharmacist or nurse before using Rebif.
Slovenian: Opozorila in previdnostni ukrepi Pred začetkom uporabe zdravila Rebif se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
English: Biological response markers (e.g., 2',5'-OAS activity, neopterin and beta 2-microglobulin) are induced by interferon beta-1a following subcutaneous doses administered to healthy volunteer subjects.
Slovenian: Interferon beta-1a inducira biološke označevalce odziva (npr. aktivnost 2',5'-OAS, neopterin in beta-2-mikroglobulin) po dajanju subkutanih odmerkov zdravim prostovoljcem.
English: • Choose an injection site.
Slovenian: • Izberite mesto injiciranja.
English: • Your doctor will tell you how to choose the correct dose.
Slovenian: • Kako izbrati pravilen odmerek vam bo razložil vaš zdravnik.
English: Intramuscular and subcutaneous administrations produce fully superimposable responses.
Slovenian: Odzivi po intramuskularni in subkutani uporabi se popolnoma prekrivajo.
English: Clinical data suggest that after 24 to 48 months of treatment with Rebif 44 micrograms, approximately 13 to 14% of patients develop persistent serum antibodies to interferon beta-1a.
Slovenian: Klinični podatki kažejo, da se po 24 do 48 mesecih zdravljenja z zdravilom Rebif 44 mikrogramov, približno pri 13 do 14 % bolnikov razvije vztrajen pojav serumskih protiteles na interferon beta-1a.
English: Any disease other than multiple sclerosis that could better explain signs and symptoms of the patient had to be excluded.
Slovenian: Izključiti je bilo treba vse druge bolezni, ki bi bolj ustrezale znakom in simptomom pri teh bolnikih, kot multipla skleroza.
English: • The other ingredients are mannitol, poloxamer 188, L-methionine, benzyl alcohol, sodium acetate, acetic acid, sodium hydroxide and water for injections.
Slovenian: • Druge sestavine zdravila so manitol, poloksamer 188, L-metionin, benzilalkohol, natrijev acetat, ocetna kislina, natrijev hidroksid in voda za injekcije.
English: INFORMATION IN BRAILLE rebif 8.8 rebif 22
Slovenian: PODATKI V BRAILLOVI PISAVI rebif 8,8 rebif 22
English: • patients with relapsing multiple sclerosis.
Slovenian: • bolnikov z multiplo sklerozo z zagoni.
English: • Hypersensitivity to natural or recombinant interferon beta or to any of the excipients listed in section 6.1.
Slovenian: • Preobčutljivost na naravni ali rekombinantni interferon beta ali katero koli pomožno snov,
English: • Your doctor will tell you how to choose the correct dose of 44 micrograms.
Slovenian: • Kako izbrati pravilen odmerek 44 mikrogramov vam bo razložil vaš zdravnik.
English: Clear to opalescent solution, with pH 3.7 to 4.1 and osmolarity 250 to 450 mOsm/L.
Slovenian: Bistra do opalescentna raztopina s pH 3,7 do 4,1 in osmolarnostjo 250 do 450 mOsm/l.
English: INFORMATION IN BRAILLE rebif 44/0.5
Slovenian: PODATKI V BRAILLOVI PISAVI rebif 44/0,5
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated-dose toxicity, and genotoxicity.
Slovenian: Predklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih odmerkih in genotoksičnosti ne kažejo posebnega tveganja za človeka.
English: Weeks 5+
Slovenian: 5. teden in naprej
English: The posology for patients who have experienced a first demyelinating event is 44 micrograms of Rebif given three times per week by subcutaneous injection.
Slovenian: Odmerjanje za bolnike, ki so doživeli prvi dogodek demielinizacije, je 44 mikrogramov zdravila Rebif trikrat na teden v obliki subkutane injekcije.
English: The pack contains 6 individual doses of 0.2 mL of Rebif 8.8 micrograms solution for injection in a 1 mL type 1 glass syringe with a stainless steel needle and 6 individual doses of 0.5 mL of Rebif 22 micrograms solution for injection in a 1 mL type 1 glass syringe with a stainless steel needle.
Slovenian: Pakiranje vsebuje 6 posameznih odmerkov po 0,2 ml zdravila Rebif 8,8 mikrogramov raztopine za injiciranje v enomililitrskih tip I steklenih injekcijskih brizgah z iglo iz nerjavečega jekla in 6 posameznih odmerkov po 0,5 ml zdravila Rebif 22 mikrogramov raztopine za injiciranje v enomililitrskih tip I steklenih injekcijskih brizgah z iglo iz nerjavečega jekla.
English: Manufacturer Merck Serono S.p.A.
Slovenian: Proizvajalec Merck Serono S.p.A.
English: Rebif has not yet been investigated in patients with primary progressive multiple sclerosis and should not be used in these patients.
Slovenian: Uporaba zdravila Rebif pri bolnikih s primarno progresivno multiplo sklerozo še ni raziskana, zato se zdravila Rebif pri teh bolnikih ne sme uporabljati.
English: Injection site necrosis (ISN) has been reported in patients using Rebif (see section 4.8).
Slovenian: Pri bolnikih, ki uporabljajo zdravilo Rebif, so poročali o nekrozi na mestu injiciranja (ISN) (glejte poglavje 4.8).
English: NOTE: do not use any areas in which you feel lumps, firm knots, or pain; talk to your doctor or healthcare professional about anything you find.
Slovenian: POZOR: Ne uporabljajte predelov, v katerih čutite zatrdline, trde vozle ali bolečino; o vsem, kar opazite, se pogovorite s svojim zdravnikom ali drugim zdravstvenim delavcem.
English: Serum neutralising antibodies against interferon beta-1a may develop.
Slovenian: Lahko se razvijejo serumska nevtralizirajoča protitelesa na interferon beta-1a.
English: The results of this study suggest that the safety profile in children (2 to 11 years old) and in adolescents (12 to 17 years old) receiving Rebif 22 micrograms or 44 micrograms subcutaneous three times per week is similar to that seen in adults.
Slovenian: Rezultati te študije kažejo, da je varnostni profil pri otrocih (starih 2 do 11 let) in mladostnikih (starih 12 do 17 let), ki so trikrat na teden subkutano prejemali zdravilo Rebif 22 mikrogramov ali 44 mikrogramov, podoben kot pri odraslih.
English: • Hold RebiDose at a right angle (90 degrees) to the injection site.
Slovenian: • Peresnik RebiDose držite pravokotno na mesto injiciranja (90°).
English: If the patient has multiple lesions, Rebif should be discontinued until healing has occurred.
Slovenian: Če ima bolnik več lezij, mora prenehati z uporabo zdravila Rebif do zacelitve lezij.
English: INFORMATION IN BRAILLE rebif 44
Slovenian: PODATKI V BRAILLOVI PISAVI rebif 44
English: For the purpose of ambulatory use, the patient may remove Rebif from the refrigerator and store it not above 25°C for one single period of up to 14 days.
Slovenian: V primeru ambulantne uporabe lahko bolnik vzame zdravilo Rebif iz hladilnika in ga shranjuje pri temperaturi do 25 °C, največ 14 dni.
English: For administration, the instructions provided in the package leaflet and in the instruction manual (Instructions for Use) provided with RebiSmart and RebiSlide should be followed.
Slovenian: Za uporabo je treba upoštevati navodilo za uporabo zdravila in navodilo za uporabo pripomočka, ki je priloženo pripomočkoma RebiSmart in RebiSlide.
English: Events were reported at various time points during treatment and may occur after several years of treatment with interferon-beta.
Slovenian: O dogodkih so poročali v različnih obdobjih zdravljenja in se lahko pojavijo po več letih zdravljenja z interferonom beta.
English: Seizures*
Slovenian: dispneja*
English: The patient may store Rebif at or below 25°C for a single period up to 14 days.
Slovenian: Bolnik lahko shranjuje zdravilo Rebif pri temperaturi 25 °C ali manj, največ 14 dni.
English: Mannitol, poloxamer 188, L-methionine, benzyl alcohol, sodium acetate, acetic acid and sodium hydroxide for pH adjustment and water for injections.
Slovenian: Manitol, poloksamer 188, L-metionin, benzilalkohol, natrijev acetat, ocetna kislina in natrijev hidroksid za uravnavanje vrednosti pH ter voda za injekcije.
English: Rebif8.8micrograms and Rebif22 micrograms are supplied in an initiation pack that is intended for use during the initial 4 weeks of treatment, during which a gradual increase in Rebif dose is recommended.
Slovenian: Rebif 8,8 mikrogramov in Rebif 22 mikrogramov sta na voljo v začetnem pakiranju, ki je namenjen za uporabo v prvih 4 tednih zdravljenja, ko se priporoča postopno povečevanje odmerka zdravila Rebif.
English: Patients who have experienced a single clinical event The usual dose is 44 micrograms (12 million IU) given three times per week.
Slovenian: Bolniki, ki so imeli en klinični dogodek Običajen odmerek je 44 mikrogramov (12 milijonov i.e.) trikrat na teden.
English: Each pre-filled pen contains 44 micrograms,
Slovenian: En napolnjen injekcijski peresnik vsebuje 44 mikrogramov,
English: • NOTE: do not use any areas in which you feel lumps, firm knots, or pain; talk to your doctor or healthcare professional about anything you find.
Slovenian: • OPOMBA: Ne uporabljajte predelov, v katerih čutite zatrdline, trdne vozle ali bolečino; o vsem, kar opazite, se pogovorite s svojim zdravnikom ali drugim zdravstvenim delavcem.
English: For the purpose of ambulatory use, you may remove Rebif from the refrigerator and store it not above 25°C for one single period of up to 14 days.
Slovenian: V primeru ambulantne uporabe lahko vzamete zdravilo Rebif iz hladilnika in ga shranjujete pri temperaturi do 25 °C, največ 14 dni.
English: Clinical data suggest that after 24 to 48 months of treatment with Rebif 22 micrograms, approximately 24% of patients develop persistent serum antibodies to interferon beta-1a.
Slovenian: Klinični podatki kažejo, da se po 24 do 48 mesecih zdravljenja z zdravilom Rebif 22 mikrogramov, približno pri 24 % bolnikov razvije vztrajen pojav serumskih protiteles na interferon beta-1a.
English: Rebif is indicated for the treatment of relapsing multiple sclerosis.
Slovenian: Zdravilo Rebif je indicirano za zdravljenje multiple skleroze z zagoni.
English: Cases of nephrotic syndrome with different underlying nephropathies including collapsing focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), membranoproliferative glomerulonephritis (MPGN) and membranous glomerulopathy (MGN) have been reported during treatment with interferon-beta products.
Slovenian: Med zdravljenjem z zdravili, ki vsebujejo interferon beta, so poročali o primerih nefrotskega sindroma pri različnih predhodnih nefropatijah, vključno s fokalno segmentno glomerulosklerozo (kolapsno spremenjeni glomeruli), glomerulonefritisom z minimalnimi spremembami, membranoproliferativnim glomerulonefritisom in membransko glomerulopatijo.
English: Rebif 22 micrograms is available as a package of 1, 3, 12, or 36 syringes.
Slovenian: Rebif 22 mikrogramov je na voljo v pakiranju po 1, 3, 12 ali 36 injekcijskih brizg.
English: At licensed posology, Rebif 44 micrograms has been demonstrated to decrease the incidence (approximately 30% over 2 years) and severity of clinical relapses in patients with at least 2 exacerbations in the previous 2 years and with an EDSS of 0-5.0 at entry.
Slovenian: Pri odobrenem odmerjanju, zdravilo Rebif 44 mikrogramov dokazano zmanjšuje pogostnost (približno 30 % v dveh letih) in intenziteto kliničnih zagonov bolezni pri bolnikih, ki so imeli najmanj dva zagona v predhodnih dveh letih in izhodiščni EDSS 0 do 5,0.
English: HOW TO USE REBIF PRE-FILLED PEN (RebiDose)
Slovenian: KAKO UPORABLJATI NAPOLNJEN INJEKCIJSKI PERESNIK ZDRAVILA REBIF (RebiDose)
English: Symptoms may include muscle pain, joint pain and swelling, and rash.
Slovenian: Simptomi lahko vključujejo bolečine v mišicah, bolečine in oteklost sklepov in izpuščaj.
English: • Muscle and joints pain
Slovenian: • bolečine v mišicah in sklepih
English: 3 pre-filled syringes.
Slovenian: 3 napolnjeni injekcijski peresniki.
English: The device (RebiSmart or RebiSlide) containing a pre-filled cartridge of Rebif must be stored in the device storage box in a refrigerator (2°C - 8°C).
Slovenian: Pripomoček (RebiSmart ali RebiSlide), ki vsebuje napolnjen vložek zdravila Rebif, shranjujte v škatli za pripomoček, v hladilniku (2 °C-8 °C).
English: At licensed posology, Rebif 22 micrograms has been demonstrated to decrease the incidence (approximately 30% over 2 years) and severity of clinical relapses in patients with at least 2 exacerbations in the previous 2 years and with an EDSS of 0-5.0 at entry.
Slovenian: Pri odobrenem odmerjanju zdravilo Rebif 22 mikrogramov dokazano zmanjšuje pogostnost (približno 30 % v dveh letih) in intenziteto kliničnih zagonov bolezni pri bolnikih, ki so imeli najmanj dva zagona v predhodnih dveh letih in izhodiščni EDSS 0 do 5,0.
English: Each pre-filled pen contains 22 micrograms,
Slovenian: En napolnjen injekcijski peresnik vsebuje 22 mikrogramov,
English: Rebif 44 micrograms is available as a package of 1, 3, 12, or 36 syringes.
Slovenian: Rebif 44 mikrogramov je na voljo v pakiranju po 1, 3, 12 ali 36 injekcijskih brizg.
English: The solution for injection in a pre-filled syringe is ready for use.
Slovenian: Raztopina za injiciranje v napolnjeni injekcijski brizgi je pripravljena za uporabo.
English: 12 pre-filled syringes.
Slovenian: 12 napolnjenih injekcijskih peresnikov.
English: How to use Rebif
Slovenian: Kako uporabljati zdravilo Rebif