FrancophonIA/ELRC3.0 huggingface dataset:
English: To re-prime the inhaler, shake the inhaler well and press down on the centre of the dose indicator twice to release a total of 2 puffs into the air away from your face.
Slovenian: Za ponovno osnovno pripravo inhalator dobro pretresite in dvakrat pritisnite na sredino kazalnika odmerka, da boste proč od obraza sprostili skupno 2 vpiha.
English: Secondary metabolic pathways include deformylation and sulfate conjugation.
Slovenian: Sekundarni poti presnove obsegata deformilacijo in sulfatno konjugacijo.
English: Symptomatic outcomes
Slovenian: Simptomatski izidi
English: The safety profile is characterised by anticholinergic and β2-adrenergic class effects related to the individual components of the combination.
Slovenian: Varnostni profil določajo antiholinergični in β2-adrenergični učinki skupine, povezani z posameznima učinkovinama v tej kombinaciji.
English: In-vitro studies indicate the glycopyrronium does not inhibit any subtype of cytochrome P450 and that there is no induction of CYP1A2, 2B6, or 3A4.
Slovenian: Študije in vitro kažejo, da glikopironij ne zavira nobene podvrste citokroma P450 in da ne inducira CYP1A2, 2B6 ali 3A4.
English: • Hold the inhaler upright, away from your face and shake it well (See Figure 4).
Slovenian: • Držite inhalator pokonci, obrnjen proč od obraza, in ga dobro pretresite (glejte sliko 4).
English: Insufficient pharmacokinetic data are available to compare exposure for other ethnicities or races.
Slovenian: Za primerjavo izpostavljenosti pri drugih etničnih pripadnostih ali rasah ni na voljo dovolj farmakokinetičnih podatkov.
English: Bevespi Aerosphere is not for use in children or adolescents below 18 years of age.
Slovenian: Zdravilo Bevespi Aerosphere ni namenjeno za uporabo pri otrocih in mladostnikih, mlajših od 18 let.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Bevespi Aerosphere in all subsets of the paediatric population in COPD (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Bevespi Aerosphere za vse podskupine pediatrične populacije pri KOPB (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: The recommended dose is two puffs twice a day.
Slovenian: Priporočeni odmerek je dva vpiha dvakrat na dan.
English: Concurrent use of either non-selective or selective β-adrenergic blockers should be avoided unless there are compelling reasons for their use.
Slovenian: Sočasni uporabi neselektivnih in selektivnih blokatorjev adrenergičnih receptorjev β se je treba izogniti, razen če je njihova uporaba nujna.
English: INNER CARTON, MULTIPACK - WITH NO BLUE BOX
Slovenian: NOTRANJA ŠKATLA SKUPNEGA PAKIRANJA - BREZ MODREGA OKENCA
English: However, if it is nearly time for your next dose, skip the missed dose.
Slovenian: Če pa je že skoraj čas za naslednji odmerek, izpustite odmerek, ki ste ga pozabili uporabiti.
English: SGRQ total score
Slovenian: Celotna ocena SGRQ
English: Do not put the pressurised container back into the actuator if it is still wet.
Slovenian: Tlačnega vsebnika ne vstavljajte nazaj v sprožilnik, če je ta še moker.
English: Glycopyrronium has similar affinity to the subtypes of muscarinic receptors M1 to M5.
Slovenian: Glikopironij ima podobno afiniteto za podvrste muskarinskih receptorjev M1 do M5.
English: • medicines called beta-blockers that may be used to treat high blood pressure or other heart problems (such as atenolol or propranolol) or to treat glaucoma (such as timolol)
Slovenian: • zdravila, imenovana blokatorji beta, ki se lahko uporabljajo za zdravljenje visokega krvnega tlaka ali drugih težav s srcem (npr. atenolol ali propranolol), ali za zdravljenje glavkoma (npr. timolol).
English: The medicine prevents the tightening of the muscles around the airways, making it easier for air to get in and out of the lungs.
Slovenian: Zdravilo prepreči skrčenje mišic okrog dihalnih poti in tako olajša vstopanje zraka v pljuča in njegovo izstopanje iz pljuč.
English: Step 5: While breathing in deeply and slowly, press down on the centre of the dose indicator until the pressurised container stops moving in the actuator and a puff of medicine has been released (See Figure 10).
Slovenian: Slika 9 5. korak: Med počasnim in globokim vdihom pritiskajte na srednji del kazalnika odmerka, dokler se tlačni vsebnik v sprožilniku ne neha premikati in se sprosti vpih zdravila (glejte sliko 10).
English: Bevespi Aerosphere should only be used during pregnancy if the expected benefits outweigh the potential risks.
Slovenian: Zdravilo Bevespi Aerosphere je med nosečnostjo dovoljeno uporabiti le, če pričakovane koristi odtehtajo možna tveganja.
English: • Press down firmly on the centre of the dose indicator until the pressurised container stops moving in the actuator.
Slovenian: • Močno pritiskajte na sredino kazalnika odmerka, dokler se tlačni vsebnik v sprožilniku ne neha premikati.
English: • you have kidney or liver problems
Slovenian: • če imate težave z ledvicami ali jetri.
English: EXP To be used within 3 months of opening the pouch.
Slovenian: EXP Porabite v 3 mesecih po odprtju vrečke.
English: An overdose of Bevespi Aerosphere may lead to exaggerated anticholinergic and/or β2-adrenergic signs and symptoms, the most frequent of which include blurred vision, dry mouth, nausea, muscle spasm, tremor, headache, palpitations and systolic hypertension.
Slovenian: Preveliko odmerjanje zdravila Bevespi Aerosphere lahko povzroči pretirane antiholinergične in/ali β2-adrenergične znake in simptome; najpogostejši so zamegljen vid, suhost ust, navzea, mišični spazmi, tremor, glavobol, palpitacije in sistolična hipertenzija.
English: This will release a puff of medicine from the mouthpiece (See Figure 5).
Slovenian: To bo sprostilo vpih zdravila iz ustnika (glejte sliko 5).
English: Figure 2a 120 puffs
Slovenian: Slika 2a 120 vpihov
English: Based on literature, and an in-vitro human hepatocyte study, metabolism plays a minor role in the overall elimination of glycopyrronium.
Slovenian: Na podlagi literature in študij na humanih hepatocitih in vitro ima presnova majhno vlogo v celotnem odstranjevanju glikopironija.
English: Studies in rats have shown adverse effects on fertility only at dose levels higher than the maximum human exposure to formoterol (see section 5.3).
Slovenian: Študije na podganah so pokazale neželene učinke na plodnost le pri odmerkih, ki so večji od največje izpostavljenosti formoterolu pri človeku (glejte poglavje 5.3).
English: The mean bronchodilator effect derived from serial FEV1 measurements at Day 1 and Week 12 from PINNACLE 1 are shown in Figure 1.
Slovenian: Povprečni bronhodilatacijski učinek na podlagi zaporednih meritev FEV1 1. dan in 12. teden v študiji PINNACLE 1 je prikazan na sliki 1.
English: Formoterol causes direct relaxation of airway smooth muscle as a consequence of the increase in cyclic AMP through activation of adenylate cyclase.
Slovenian: Formoterol neposredno sprošča gladke mišice dihal, kot posledica zvišanja cikličnega AMP z aktivacijo adenilat-ciklaze.
English: In PINNACLE 2, the results were similar to those observed in PINNACLE 1.
Slovenian: V študiji PINNACLE 2 so bili rezultati podobni tistim v študiji PINNACLE 1.
English: Glycopyrronium is primarily cleared from the systemic circulation by renal excretion and hepatic impairment would therefore not be expected to lead to unsafe systemic exposure.
Slovenian: Glikopironij se iz sistemskega obtoka odstrani predvsem z izločanjem skozi ledvice, zato ni pričakovati, da bi okvara jeter povzročila sistemsko izpostavljenost, ki ne bi bila varna.
English: The tabulated list of adverse reactions is based on the experience with Bevespi Aerosphere in clinical trials and experience with the individual components.
Slovenian: Seznam neželenih učinkov v preglednici temelji na izkušnjah z zdravilom Bevespi Aerosphere v kliničnih preskušanjih in izkušnjah z njegovima posameznima učinkovinama.
English: The effect of renal impairment on the exposure to glycopyrronium and formoterol for up to 12 weeks was evaluated in a population pharmacokinetic analysis.
Slovenian: Vpliv okvare ledvic na izpostavljenost glikopironiju in formoterolu do 12 tednov so ovrednotili v populacijski farmakokinetični analizi.
English: Bevespi Aerosphere is available in packs containing 1 inhaler with 120 puffs and in multipacks comprising 3 inhalers, each containing 120 puffs.
Slovenian: Zdravilo Bevespi Aerosphere je na voljo v pakiranju, ki vsebuje 1 inhalator s 120 vpihi in v skupnem pakiranju, sestavljenem iz 3 inhalatorjev, od katerih vsak vsebuje 120 vpihov.
English: Health-related quality of life:
Slovenian: Zdravstvena kakovost življenja
English: Step 2: Shake the inhaler well before each use (See Figure 7).
Slovenian: Slika 6 2. korak: Inhalator pred vsako uporabo dobro pretresite (glejte sliko 7).
English: COPD is a long-term disease of the airways in the lungs, which is often caused by smoking.
Slovenian: KOPB je dolgotrajna bolezen dihal in pljuč; pogosto jo povzroči kajenje.
English: Turn the actuator upside down and rinse the actuator again through the mouthpiece for about 30 seconds (See Figure 16).
Slovenian: Obrnite sprožilnik na glavo in ga skozi ustnik znova izpirajte približno 30 sekund (glejte sliko 16).
English: Step 4: Close your lips around the mouthpiece and tilt your head back, keeping your tongue below the mouthpiece (See Figure 9).
Slovenian: Slika 8 4. korak: Stisnite ustnice okrog ustnika in nagnite glavo rahlo nazaj; jezik držite pod ustnikom (glejte sliko 9).
English: What Bevespi Aerosphere is and what it is used for What you need to know before you use Bevespi Aerosphere How to use Bevespi Aerosphere Possible side effects
Slovenian: Kaj je zdravilo Bevespi Aerosphere in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Bevespi Aerosphere Kako uporabljati zdravilo Bevespi Aerosphere Možni neželeni učinki
English: Pressurised container
Slovenian: Tlačni vsebnik
English: Step 5: Look into the actuator and the mouthpiece to make sure any medicine build-up has been completely washed away.
Slovenian: 5. korak: Preglejte sprožilnik in ustnik in se tako prepričajte, da ste povsem odplaknili vse obloge zdravila.
English: It is unlikely that Bevespi Aerosphere administered at the recommended dose will affect fertility in humans.
Slovenian: Ni verjetno, da bi zdravilo Bevespi Aerosphere, uporabljeno v priporočenem odmerku, vplivalo na plodnost pri človeku.
English: COPD exacerbations:
Slovenian: Poslabšanja KOPB:
English: A double dose should not be taken to make up for a forgotten dose.
Slovenian: V primeru pozabljenega odmerka ne sme uporabiti dvojnega odmerka, da bi nadomestil pozabljenega.
English: Concomitant treatment with methylxanthine derivatives, steroids, or non-potassium-sparing diuretics may potentiate the possible initial hypokalaemic effect of β2-adrenergic agonists, therefore, caution is advised in their concomitant use (see section 4.4).
Slovenian: Sočasno zdravljenje z metilksantinskimi derivati, steroidi ali diuretiki, ki ne varčujejo s kalijem, lahko okrepi možni začetni hipokaliemični učinek agonistov adrenergičnih receptorjev β2, zato je pri njihovi sočasni uporabi potrebna previdnost (glejte poglavje 4.4).
English: If β-adrenergic blockers are required (including eye drops), cardioselective β-adrenergic blockers are preferred, although they should also be administered with caution.
Slovenian: Če so blokatorji adrenergičnih receptorjev β (vključno s kapljicami za oči) potrebni, imajo prednost kardioselektivni blokatorji β, čeprav je treba tudi te uporabljati previdno.
English: The effect of cimetidine, a probe inhibitor of OCT2 and MATE1, on inhaled glycopyrronium disposition showed a limited increase in its total systemic exposure (AUC0-t) by 22% and a slight decrease in renal clearance by 23% due to co-administration of cimetidine.
Slovenian: Vpliv cimetidina, testnega zaviralca OCT2 in MATE1, na izpostavljenost inhaliranemu glikopironiju je pokazal omejeno povečanje njegove celotne sistemske izpostavljenosti (AUC0-t) za 22 % in rahlo zmanjšanje ledvičnega očistka za 23 % zaradi sočasne uporabe cimetidina.
English: No significant effects attributable to glycopyrronium were seen.
Slovenian: Opazili niso nobenih pomembnih učinkov, ki bi jih bilo mogoče pripisati glikopironiju.
English: • The dose indicator display window will move after every 10 puffs.
Slovenian: • Oznake v okencu kazalnika odmerkov se bodo premaknile na vsakih 10 vpihov.
English: • you have diabetes
Slovenian: • če imate sladkorno bolezen.
English: You may be able to use a ‘spacer' with your inhaler.
Slovenian: Morda boste inhalator lahko uporabili skupaj z "ustnikom".
English: Warning: Do not break, puncture or burn the pressurised container, even when apparently empty.
Slovenian: Opozorilo: Tlačnega vsebnika ne odpirajte, ne predirajte in ne zažigajte, tudi če se zdi prazen.
English: OUTER CARTON, MULTIPACK - WITH BLUE BOX
Slovenian: ZUNANJA ŠKATLA SKUPNEGA PAKIRANJA - Z MODRIM OKENCEM
English: Do not use Bevespi Aerosphere if:
Slovenian: Ne uporabljajte zdravila Bevespi Aerosphere, če:
English: How to store Bevespi Aerosphere Contents of the pack and other information Instructions for use
Slovenian: Shranjevanje zdravila Bevespi Aerosphere Vsebina pakiranja in dodatne informacije Navodila za uporabo zdravila
English: After IV administration of a 0.2 mg dose of radiolabelled glycopyrronium, 85% of the dose was recovered in urine 48 hours post dose and some of radioactivity was also recovered in bile.
Slovenian: Po intravenski uporabi 0,2-mg odmerka radioaktivno označenega glikopironija se je 85 % odmerka pojavilo v urinu v 48 urah po odmerku, nekaj radioaktivnosti pa se je pojavilo tudi v žolču.
English: Before you use Bevespi Aerosphere for the first time Before you use Bevespi Aerosphere for the first time, make sure that the pointer on the dose indicator is pointing to the right of the “120” inhalation mark in the dose indicator display window (See Figure
Slovenian: Preden prvič uporabite zdravilo Bevespi Aerosphere, se prepričajte, da kazalec na kazalniku odmerka kaže desno od oznake vpihov "120" (v okencu kazalnika odmerka) (glejte sliko 1).
English: These include medicines for the treatment of: o depression (such as monoamine oxidase inhibitors or tricyclic antidepressants), o bacterial infections (such as erythromycin, clarithromycin, telithromycin), o allergic reactions (anti-histamines).
Slovenian: Mednje sodijo zdravila, ki jih uporabljamo pri zdravljenju: o depresije (kot so zaviralci monoaminooksidaze ali triciklični antidepresivi), o bakterijskih okužb (kot so eritromicin, klaritromicin in telitromicin), o alergijskih reakcij (antihistaminiki).
English: Step 6: Let the actuator air-dry overnight (See Figure 17).
Slovenian: 6. korak: Pustite sprožilnik, da se čez noč posuši na zraku (glejte sliko 17).
English: PINNACLE 4 used TDI.
Slovenian: V študiji PINNACLE 4 so uporabili TDI.
English: • you have prostate problems, or difficulty passing urine
Slovenian: • če imate težave s prostato ali z odvajanjem urina.
English: Studies evaluating the effect of renal impairment on the pharmacokinetics of glycopyrronium and formoterol have not been conducted.
Slovenian: Študij za ovrednotenje učinka okvare ledvic na farmakokinetiko glikopironija in formoterola niso izvedli.
English: You may notice that your heart is beating faster than usual, you feel shaky, you have visual disturbances, have a dry mouth, or have a headache or feel nauseous (sick).
Slovenian: Morda boste opazili hitrejši srčni utrip kot običajno, občutek tresenja, motnje vida, suha usta, glavobol ali občutek slabosti s siljenjem na bruhanje.
English: In-vitro studies indicate that formoterol does not inhibit the CYP450 enzymes at therapeutically relevant concentrations.
Slovenian: Študije in vitro kažejo, da formoterol v terapevtsko pomembnih koncentracijah ne zavira encimov CYP450.
English: The toxicity observed in studies with the combination of glycopyrronium and formoterol in dogs were associated with the pharmacological actions of formoterol, including effects mainly on the cardiovascular system, consisting of hyperaemia, tachycardia, arrhythmias and myocardial lesions.
Slovenian: Toksičnost, opažena v študijah s kombinacijo glikopironija in formoterola pri psih, je bila povezana s farmakološkim delovanjem formoterola, vključno z učinki predvsem na srčno-žilni sistem, ki so obsegali hiperemijo, tahikardijo, motnje srčnega ritma in lezije miokarda.
English: Estimated glomerular filtration rate (eGFR) varied from 30-196 mL/min, representing a range of moderate to no renal impairment.
Slovenian: Ocenjena hitrost glomerularne filtracije (eGFR) je segala od 30 do 196 ml/min; to ustreza stanju od zmerne okvare ledvic do brez okvare ledvic.
English: These are known pharmacological manifestations seen after administration of high doses of adrenoceptor agonists.
Slovenian: To so znani farmakološki učinki po uporabi velikih odmerkov agonistov adrenergičnih receptorjev .
English: In the airways, it exhibits pharmacological effects through inhibition of the M3 receptor at the smooth muscle leading to bronchodilation.
Slovenian: V dihalih se njegovi farmakološki učinki kažejo z zavrtjem receptorjev M3 v gladkih mišicah; to povzroči bronhodilatacijo.
English: The primary metabolism of formoterol is by direct glucuronidation and by O-demethylation followed by conjugation to inactive metabolites.
Slovenian: Primarna presnova formoterola poteka z neposredno glukuronidacijo in O-demetilacijo, čemur sledi konjugacija neaktivnih presnovkov.
English: The typical clearance (CL/F) of glycopyrronium was 124 L/h.
Slovenian: Značilni očistek (CL/F) glikopironija je bil 124 l/h.
English: The pressurised container should not be broken, punctured or burnt, even when apparently empty.
Slovenian: Tlačnega vsebnika ne lomite, ne prebadajte in ne sežigajte, tudi če se zdi prazen.
English: There are no data on the use of Bevespi Aerosphere in pregnant women.
Slovenian: Podatkov o uporabi zdravila Bevespi Aerosphere pri nosečnicah ni.
English: • you have low levels of potassium in the blood
Slovenian: • če imate nizko koncentracijo kalija v krvi.
English: The clinical development program for Bevespi Aerosphere included three 24-week, randomised, double-blind, placebo-controlled, parallel-group pivotal Phase III studies in 5,433 patients with moderate to very severe COPD (PINNACLE 1, PINNACLE 2 and PINNACLE 4).
Slovenian: Program kliničnega razvoja zdravila Bevespi Aerosphere je obsegal tri 24-tedenske randomizirane, dvojno slepe, s placebom kontrolirane ključne študije III. faze z vzporednimi skupinami pri 5433 bolnikih z zmerno do zelo hudo KOPB (PINNACLE 1, PINNACLE 2 in PINNACLE 4).
English: Please read the instructions for use at the end of this leaflet.
Slovenian: Preberite navodila za uporabo zdravila na hrbtni strani tega navodila za uporabo.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking Bevespi Aerosphere.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom ali farmacevtom, preden vzamete zdravilo Bevespi Aerosphere.
English: • you have thyroid gland problems (called ‘thyrotoxicosis')
Slovenian: • če imate težave z žlezo ščitnico (imenovane "tirotoksikoza").
English: In-vitro glycopyrronium is a substrate for the renal transporters OCT2 and MATE1/2K.
Slovenian: In vitro je glikopironij substrat ledvičnih prenašalcev OCT2 in MATE1/2K.
English: However, because formoterol is primarily eliminated via hepatic metabolism, an increased exposure can be expected in patients with severe liver impairment.
Slovenian: Toda, ker se formoterol v prvi vrsti odstrani s presnovo v jetrih, je pri bolnikih s hudo okvaro jeter mogoče pričakovati večjo izpostavljenost.
English: Steady state is achieved within 2-3 days of repeated dosing of Bevespi Aerosphere, and the extent of exposure is approximately 2.3 times and 1.5 times higher than after the first dose, for glycopyrronium and formoterol, respectively.
Slovenian: Stanje dinamičnega ravnovesja je doseženo v 2 do 3 dneh ponavljajoče se uporabe zdravila Bevespi Aerosphere in obseg izpostavljenosti je v primerjavi s tisto po prvem odmerku približno 2,3-krat večji za glikopironij in približno 1,5-krat večji za formoterol.
English: Figure 14 Step 1: Take the pressurised container out of the actuator (See Figure 15).
Slovenian: Slika 14 1. korak: Vzemite tlačni vsebnik iz sprožilnika (glejte sliko 15).
English: Hypokalaemia β2-adrenergic agonists may produce significant hypokalaemia, which may increase the susceptibility to cardiac arrhythmias.
Slovenian: Agonisti adrenergičnih receptorjev β2 lahko povzročijo pomembno hipokaliemijo, ta pa lahko poveča dovzetnost za motnje srčnega ritma.
English: Following inhaled administration of Bevespi Aerosphere in subjects with COPD, glycopyrronium Cmax occurred at approximately 5 minutes, and formoterol Cmax occurred within 20 to 60 minutes.
Slovenian: Po inhaliranju zdravila Bevespi Aerosphere je bila pri preiskovancih s KOPB Cmax glikopironija dosežena v približno 5 minutah in Cmax formoterola v približno 20 do 60 minutah.
English: Bevespi Aerosphere delivers the active ingredients directly to the airways in your lungs as you breathe in.
Slovenian: Zdravilo Bevespi Aerosphere odda učinkovini neposredno v dihalne poti v pljučih, ko vdihnete.
English: The systemic exposure (AUC0-12) in subjects with COPD with moderate-severe renal impairment (eGFR of 30-45 mL/min) is approximately 30% higher for glycopyrronium compared to subjects with COPD with normal renal function (eGFR of >90 mL/min).
Slovenian: Sistemska izpostavljenost (AUC0-12) glikopironiju je pri preiskovancih s KOPB in zmerno hudo okvaro ledvic (eGFR 30-45 ml/min) približno 30 % večja kot pri preiskovancih s KOPB in normalnim delovanjem ledvic (eGFR > 90 ml/min).
English: Following inhalation of the glycopyrronium and formoterol combination, the pharmacokinetics of each component was similar to those observed when each active substance was administered separately.
Slovenian: Po inhaliranju kombinacije glikopironija in formoterola je bila farmakokinetika vsake posamezne učinkovine podobna kot med uporabo vsake učinkovine posamezno.
English: Write the date the pouch is opened on the inhaler label in the space provided.
Slovenian: Datum odprtja vrečke vpišite na predvideni prostor na nalepki inhalatorja.
English: Dose indicator
Slovenian: Kazalnik odmerka
English: Since glycopyrronium is eliminated mainly by the renal route, drug interaction could potentially occur with medicinal products affecting renal excretion mechanisms.
Slovenian: Ker se glikopironij izloča predvsem skozi ledvice, bi se morda lahko pojavila medsebojna delovanja z zdravili, ki vplivajo na mehanizem izločanja skozi ledvice.
English: Step 8: Re-prime your Bevespi Aerosphere inhaler after each cleaning.
Slovenian: 8. korak: Po vsakem čiščenju inhalatorja Bevespi Aerosphere znova opravite osnovno pripravo.
English: • The colour in the dose indicator display window will change to red, as shown in the shaded area, when there are only 20 puffs of medicine left in your inhaler (See Figure 2d).
Slovenian: • Ko bo v inhalatorju preostalo le še 20 vpihov zdravila, se bo barva okenca kazalnika odmerka spremenila v rdečo, kot je prikazano na zasenčeni površini (glejte sliko 2d).
English: These include: o corticosteroids that you take by mouth (such as prednisolone), o diuretics (such as furosemide or hydrochlorothiazide) used for high blood pressure, o some medicines used to treat breathing conditions called methylxanthines (such as theophylline);
Slovenian: Med takšnimi so: o kortikosteroidi, ki jih zaužijete (peroralni kortikosteroidi), na primer prednizolon, o diuretiki (na primer furosemid ali hidroklorotiazid), ki jih uporabljamo pri zvišanem krvnem tlaku, o nekatera zdravila, imenovana metilksantini, ki se uporabljajo za zdravljenje težav z dihanjem (na primer teofilin).