FrancophonIA/ELRC3.0 huggingface dataset:
English: Ketoconazole (400 mg daily) increased tadalafil (20 mg) exposure (AUC) 4-fold and Cmax by 22 %.
Slovenian: Ketokonazol (400 mg na dan) je povečal izpostavljenost (AUC) tadalafilu (20 mg) za 4-krat in Cmax za 22 %.
English: In a subsequent study, 217 patients who were treatmentnaïve to PDE5 inhibitors were randomized to CIALIS 5 mg once a day vs. placebo.
Slovenian: V nadaljnji študiji so 217 bolnikov, ki se predhodno niso zdravili z zaviralci PDE5, naključno razvrstili v jemanje zdravila CIALIS v odmerku 5 mg enkrat na dan in jemanje placeba.
English: These include: migraine, swelling of the face, serious allergic reaction which causes swelling of the face or throat, serious skin rashes, some disorders affecting blood flow to the eyes, irregular heartbeats, angina and sudden cardiac death.
Slovenian: - migreno, otekanje obraza, resno alergijsko reakcijo, ki povzroči otekanje obraza in grla, resne kožne izpuščaje, nekatere motnje, ki vplivajo na dotok krvi v oči, nepravilno bitje srca, angino pektoris in nenadno srčno smrt.
English: CIALIS is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure (see section 4.4).
Slovenian: Zdravilo CIALIS je kontraindicirano pri bolnikih, ki so izgubili vid na enem očesu zaradi nearteritične anteriorne ishemične optične nevropatije (NAION), tudi če ta dogodek ni bil povezan s predhodnim jemanjem zaviralcev PDE5 (glejte poglavje 4.4).
English: Nederland Eli Lilly Nederland B.V.
Slovenian: Eli Lilly Nederland B.V.
English: Method of administration CIALIS is available as 2.5, 5, 10, and 20 mg film-coated tablets for oral use.
Slovenian: Zdravilo CIALIS je na voljo v obliki 2,5 mg, 5 mg, 10 mg in 20 mg filmsko obloženih tablet za peroralno uporabo.
English: Tadalafil is predominantly metabolised by the cytochrome P450 (CYP) 3A4 isoform.
Slovenian: Tadalafil se presnavlja predvsem s citokromom P450 (CYP), izoobliko 3A4.
English: In order for tadalafil to be effective for the treatment of erectile dysfunction, sexual stimulation is required.
Slovenian: Za učinkovitost tadalafila pri zdravljenju erektilne disfunkcije je potrebna spolna stimulacija.
English: CIALIS improves blood flow to, and relaxes the muscles of, the prostate and bladder which may reduce symptoms of benign prostatic hyperplasia.
Slovenian: Zdravilo CIALIS izboljša dotok krvi v prostato in sečni mehur ter sprošča mišice prostate in mehurja, s čimer lahko zmanjša simptome benigne hiperplazije prostate.
English: Benign prostatic hyperplasia in adult men
Slovenian: Benigna hiperplazija prostate pri odraslih moških
English: How to take CIALIS
Slovenian: Kako jemati zdravilo CIALIS
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER Eli Lilly Nederland B.V.
Slovenian: IME IN NASLOV IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM Eli Lilly Nederland B.V.
English: Cytochrome P450 inducers
Slovenian: Zaviralci citokroma P450
English: (2) Postmarketing surveillance reported adverse reactions not observed in placebo-controlled clinical trials.
Slovenian: (2) Neželeni učinki o katerih so poročali med spremljanjem v obdobju trženja tadalafila in jih v s placebom kontroliranih kliničnih študijah niso opazili.
English: There is no relevant use of CIALIS in the paediatric population with regard to the treatment of erectile dysfunction.
Slovenian: Zdravilo CIALIS ni namenjeno za uporabo pri pediatrični populaciji za zdravljenje erektilne disfunkcije.
English: Tadalafil administered to healthy subjects produced no significant difference compared to placebo in supine systolic and diastolic blood pressure (mean maximal decrease of 1.6/0.8 mm Hg, respectively), in standing systolic and diastolic blood pressure (mean maximal decrease of 0.2/4.6 mm Hg, respectively), and no significant change in heart rate.
Slovenian: Tadalafil, ki so ga dali zdravim posameznikom, v primerjavi s placebom ni povzročil pomembne razlike sistoličnega oz. diastoličnega krvnega tlaka leže (povprečni maksimalni padec 1,6 mmHg oziroma 0,8 mmHg), sistoličnega oz. diastoličnega krvnega tlaka stoje (povprečni maksimalni padec 0,2 mmHg oziroma 4,6 mmHg) ter nobene pomembne spremembe srčne frekvence.
English: Dose adjustments are not required in patients with mild to moderate renal impairment.
Slovenian: Pri bolnikih z blago do zmerno okvaro ledvic prilagajanja odmerkov niso potrebna.
English: CIALIS 20 mg is available in blister packs containing 2, 4, 8, 10 or 12 tablets.
Slovenian: Zdravilo CIALIS 20 mg je na voljo v pretisnih omotih z 2, 4, 8, 10 ali 12 tabletami.
English: CIALIS 10 mg film-coated tablets Aluminium/PVC blisters in cartons of 4 film-coated tablets.
Slovenian: CIALIS 10 mg filmsko obložene tablete Pretisni omoti aluminij/PVC v škatlah s po 4 filmsko obloženimi tabletami.
English: In a 12-week study performed in 186 patients (142 tadalafil, 44 placebo) with erectile dysfunction secondary to spinal cord injury, tadalafil significantly improved the erectile function leading to a mean per-subject proportion of successful attempts in patients treated with tadalafil 10 or 20 mg (flexible-dose, on demand) of 48 % as compared to 17 % with placebo.
Slovenian: V 12-tedenski študiji, ki so jo izvedli pri 186 bolnikih (142 jih je jemalo tadalafilu, 44 pa placebo) z erektilno disfunkcijo zaradi poškodbe hrbtenjače, je tadalafil bistveno izboljšal erektilno funkcijo, kar je vodilo v povprečno sorazmerno število uspešnih poskusov na osebo pri bolnikih, zdravljenih s tadalafilom 10 ali 20 mg (prilagodljiv odmerek, po potrebi) pri 48 % bolnikov, v primerjavi s 17 % pri placebu.
English: The randomised, double-blind, placebo-controlled, parallel, 3-arm study of tadalafil was conducted in 331 boys aged 7-14 years with DMD receiving concurrent corticosteroid therapy.
Slovenian: Randomizirano, dvojno slepo, s placebom nadzorovano paralelno študijo tadalafila s tremi skupinami preiskovancev so opravili s 331 fanti, starimi od 7 do
English: CIALIS 5 mg is available in blister packs containing 14, 28 or 84 tablets.
Slovenian: Zdravilo CIALIS 5 mg je na voljo v pretisnih omotih s 14, 28 ali 84 tabletami.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to medical prescription
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja zdravila je le na recept.
English: CIALIS has negligible influence on the ability to drive or use machines.
Slovenian: 4.7 Vpliv na sposobnost vožnje in upravljanja strojev Zdravilo CIALIS ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
English: There is limited clinical data on the safety of CIALIS in patients with severe hepatic impairment (Child-Pugh Class C); if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician.
Slovenian: Pri bolnikih s hudo okvaro jeter (razred C po Child-Pughu) so na voljo le omejeni klinični podatki o varnosti zdravila CIALIS; v kolikor ga predpišemo, naj zdravnik, ki zdravilo predpiše, skrbno ovrednoti razmerje med koristmi in tveganjem pri posamezniku.
English: PHARMACEUTICAL FORM AND CONTENTS 4 film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 4 filmsko obložene tablete
English: CIALIS 20 mg film-coated tablets Aluminium/PVC blisters in cartons of 2, 4, 8, 10 and 12 film-coated tablets.
Slovenian: CIALIS 20 mg filmsko obložene tablete Pretisni omoti aluminij/PVC v škatlah s po 2, 4, 8, 10 in 12 filmsko obloženimi tabletami.
English: Ritonavir, a protease inhibitor (200 mg twice daily), which is an inhibitor of CYP3A4, CYP2C9, CYP2C19, and CYP2D6, increased tadalafil (20 mg) exposure (AUC) 2-fold with no change in Cmax.
Slovenian: Ritonavir, zaviralec proteaze (200 mg dvakrat na dan), ki je zaviralec CYP3A4, CYP2C9, CYP2C19 in CYP2D6, je povečal izpostavljenost (AUC) tadalafilu
English: Aluminium/PVC blisters in cartons of 28 film-coated tablets.
Slovenian: Pretisni omoti aluminij/PVC v škatlah s po 28 filmsko obloženimi tabletami.
English: PHARMACEUTICAL FORM AND CONTENTS 28 film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 28 filmsko obloženih tablet
English: CIALIS 2.5 mg is available in blister packs containing 28 tablets.
Slovenian: Zdravilo CIALIS 2,5 mg je na voljo v pretisnih omotih z 28 tabletami.
English: In a study to assess the effects of tadalafil on vision, no impairment of colour discrimination (blue/green) was detected using the Farnsworth-Munsell 100-hue test.
Slovenian: V študiji ugotavljanja učinkov tadalafila na vid z uporabo Farnsworth-Munsellovega testa s
English: There was no evidence of teratogenicity, embryotoxicity or foetotoxicity in rats or mice that received up to 1000 mg/kg/day tadalafil.
Slovenian: Pri podganah ali miših, ki so prejemale do 1000 mg/kg/dan tadalafila, ni bilo dokazov teratogenosti, embriotoksičnosti ali fetotoksičnosti.
English: In patients who are taking alpha1 blockers, concomitant administration of CIALIS may lead to symptomatic hypotension in some patients (see section 4.5).
Slovenian: Pri bolnikih, ki jemljejo antagoniste adrenergičnih receptorjev alfa1, lahko sočasno dajanje zdravila CIALIS pri nekaterih bolnikih povzroči simptomatsko hipotenzijo (glejte poglavje 4.5).
English: CIALIS 5 mg is used to treat adult men with: - erectile dysfunction.
Slovenian: Zdravilo CIALIS 5 mg je namenjeno zdravljenju odraslih moških z:
English: Abdominal pain, Vomiting, Nausea, Gastro-oesophageal reflux
Slovenian: bruhanje, navzea, gastroezofagealni refluks
English: CIALIS 10 mg is available in blister packs containing 4 tablets.
Slovenian: Zdravilo CIALIS 10 mg je na voljo v pretisnih omotih s 4 tabletami.
English: Major classes of antihypertensive medicinal products were studied, including calcium channel blockers (amlodipine), angiotensin converting enzyme (ACE) inhibitors (enalapril), beta-adrenergic receptor blockers (metoprolol), thiazide diuretics (bendrofluazide), and angiotensin II receptor blockers (various types and doses, alone or in combination with thiazides, calcium channel blockers, beta-blockers, and/or alpha-blockers).
Slovenian: Preučevali so poglavitne razrede antihipertenzivnih zdravil, vključno z antagonisti kalcijevih kanalčkov (amlodipin), zaviralci angiotenzin konvertaze (enalapril), antagonisti adrenergičnih receptorjev beta (metoprolol), tiazidnimi diuretiki (bendroflumetiazid) in antagonisti receptorjev angiotenzina II (različni tipi in odmerki, posamezno ali v kombinaciji s tiazidi, zaviralci kalcijevih kanalčkov, antagonisti adrenergičnih receptorjev beta in/ali antagonisti adrenergičnih receptorjev alfa).
English: Urticaria, Stevens-Johnson syndrome2, Exfoliative dermatitis2, Hyperhydrosis (sweating)
Slovenian: Bolezni kože in podkožja izpuščaj koprivnica, StevensJohnsonov sindrom2, eksofoliativni dermatitis2, hiperhidroza (znojenje)
English: Tadalafil has no effect in the absence of sexual stimulation.
Slovenian: Tadalafil brez spolne stimulacije nima učinka.
English: 5.2 Pharmacokinetic properties
Slovenian: 5.2 Farmakokinetične lastnosti Absorpcija
English: Tadalafil at doses of 2.5, 5, and 10 mg taken once a day was initially evaluated in 3 clinical studies involving 853 patients of various ages (range 21-82 years) and ethnicities, with erectile dysfunction of various severities (mild, moderate, severe) and etiologies.
Slovenian: Tadalafil v odmerkih od 2,5 mg, 5 mg in 10 mg enkrat na dan so prvotno vrednotili v 3 kliničnih študijah, ki so zajemale 853 bolnikov različnih starosti (od 21-82 let) in narodnosti, z erektilno disfunkcijo različnih resnosti (blaga, zmerna, huda) in etiologij.
English: In these patients the recommended dose is 5 mg taken once a day at approximately the same time of day.
Slovenian: Pri teh bolnikih je priporočeni odmerek 5 mg, zaužit enkrat na dan ob približno istem času dneva.
English: Nervous system disorders Headache
Slovenian: Bolezni živčevja glavobol omotica možganska kap1
English: Prior to initiating treatment with tadalafil for benign prostatic hyperplasia patients should be examined to rule out the presence of carcinoma of the prostate and carefully assessed for cardiovascular conditions (see section 4.3).
Slovenian: Pred uvedbo zdravljenja benigne hiperplazije prostate s tadalafilom je treba bolnike pregledati in izključiti prisotnost karcinoma prostate ter natančno oceniti njihove morebitne srčno-žilne bolezni
English: Transporters
Slovenian: Prenašalci
English: Most patients reported erectile dysfunction of at least 1 year in duration.
Slovenian: Večina bolnikov je poročala o erektilni disfunkciji,
English: For the treatment of erectile dysfunction
Slovenian: Za zdravljenje erektilne disfunkcije
English: Tadalafil exposure (AUC) in subjects with mild and moderate hepatic impairment (Child-Pugh Class A and B) is comparable to exposure in healthy subjects when a dose of 10 mg is administered.
Slovenian: Pri dajanju 10 mg odmerka je izpostavljenost tadalafilu (AUC) pri osebah z blago in zmerno okvaro jeter (razreda A in B po Child-Pughu) primerljiva z izpostavljenostjo pri zdravih osebah.
English: Cases of sudden hearing loss have been reported after the use of tadalafil.
Slovenian: Po uporabi tadalafila so poročali o primerih nenadne izgube sluha.
English: Renal insufficiency
Slovenian: Insuficienca ledvic
English: Men with diabetes Dose adjustments are not required in diabetic patients.
Slovenian: Moški s sladkorno boleznijo Pri bolnikih s sladkorno boleznijo odmerkov ni potrebno prilagajati.
English: • Drinking alcohol may affect your ability to get an erection so avoid excessive drinking with CIALIS.
Slovenian: • Pitje alkohola lahko vpliva na vašo sposobnost doseganja erekcije, zato se pri jemanju zdravila
English: The recommended dose of CIALIS is 10 mg taken prior to anticipated sexual activity and with or without food.
Slovenian: Priporočeni odmerek zdravila CIALIS je 10 mg, zaužit pred pričakovano spolno aktivnostjo, s hrano ali brez nje.
English: When dogs were treated there was reduced sperm development in the testes.
Slovenian: Plodnost Ko so zdravilo dajali psom, so v modih opazili zmanjšano nastajanje sperme v modih.
English: In general, the recommended dose is 10 mg taken prior to anticipated sexual activity and with or without food.
Slovenian: Običajen priporočeni odmerek je 10 mg, zaužit pred pričakovano spolno aktivnostjo, s hrano ali brez nje.
English: Tachycardia, Palpitations
Slovenian: palpitacijami in tahikardijo.
English: 4.4 Special warnings and precautions for use
Slovenian: 4.4 Posebna opozorila in previdnostni ukrepi Pred zdravljenjem z zdravilom CIALIS
English: Steady-state plasma concentrations are attained within 5 days of once-daily dosing.
Slovenian: Plazemske koncentracije v stanju dinamičnega ravnovesja so dosežene v 5 dneh odmerjanja enkrat na dan.
English: Tablet core: lactose monohydrate, croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate.
Slovenian: Jedro tablete: laktoza monohidrat, natrijev karmelozat, premreženi, hidroksipropilceluloza, mikrokristalna celuloza, natrijev lavrilsulfat, magnezijev stearat.
English: Prolonged erections Priapism, Penile haemorrhage,
Slovenian: Motnje reprodukcije in dojk podaljšane erekcije priapizem, krvavitev iz penisa, hematospermija
English: In the two primary efficacy studies of general populations, the mean per-subject proportion of successful intercourse attempts were 57 and 67 % on CIALIS 5 mg, 50 % on CIALIS 2.5 mg as compared to 31 and 37 % with placebo.
Slovenian: V dveh študijah primarne učinkovitosti pri splošni populaciji je bilo v povprečju pri bolnikih, zdravljenih z zdravilom CIALIS 5 mg, uspešnih 57 % in 67 % poskusov spolnega odnosa, pri bolnikih, zdravljenih z zdravilom CIALIS v odmerku 2,5 mg, pa 50 %, v primerjavi z 31 in 37 % pri placebu.
English: Your doctor may adjust the dose to 2.5 mg based on your response to CIALIS.
Slovenian: Glede na vaš odziv na zdravilo CIALIS vam bo vaš zdravnik morda prilagodil odmerek na 2,5 mg. Tega boste prejeli kot 2,5 mg tableto.
English: For once-a-day evaluation of tadalafil at doses of 2.5, 5, and 10 mg 3 clinical studies were initially conducted involving 853 patients of various ages (range 21-82 years) and ethnicities, with erectile dysfunction of various severities (mild, moderate, severe) and etiologies.
Slovenian: Za oceno, izvedeno enkrat na dan, za tadalafil v odmerkih 2,5 mg, 5 mg in 10 mg so bile prvotno opravljene 3 klinične študije, ki so zajemale 853 bolnikov različnih starosti (od 21-82 let) in narodnosti, z erektilno disfunkcijo različnih resnosti (blaga, zmerna, huda) in etiologij.
English: A CYP3A4 inducer, rifampicin, reduced tadalafil AUC by 88 %, relative to the AUC values for tadalafil alone (10 mg).
Slovenian: Induktorji citokroma P450 Induktor CYP3A4, rifampicin, je AUC tadalafila zmanjšal za 88 % v primerjavi z vrednostmi AUC za sam tadalafil (10 mg).
English: In clinical studies, tadalafil was shown to augment the hypotensive effects of nitrates.
Slovenian: V kliničnih študijah je bilo dokazano, da tadalafil okrepi hipotenzivne učinke nitratov.
English: The recommended dose is one 5 mg tablet taken once a day at approximately the same time of the day.
Slovenian: Priporočeni odmerek je ena 5 mg tableta enkrat na dan ob približno istem času dneva.
English: Thus, in a patient prescribed any dose of CIALIS (2.5 mg-20 mg), where nitrate administration is deemed medically necessary in a life-threatening situation, at least 48 hours should have elapsed after the last dose of CIALIS before nitrate administration is considered.
Slovenian: Zato naj pri bolniku, ki ima predpisan katerikoli odmerek zdravila CIALIS (2,5 mg-20 mg) in kjer je dajanje nitrata zdravstveno nujno v življenje ogrožajoči situaciji, preden razmislimo o dajanju nitrata preteče vsaj 48 ur po zadnjem odmerku zdravila CIALIS.
English: CIALIS 20 mg film-coated tablets Each tablet contains 20 mg tadalafil.
Slovenian: CIALIS 20 mg filmsko obložene tablete Ena tableta vsebuje 20 mg tadalafila.
English: Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.
Slovenian: Tadalafil v odmerku 10 in 20 mg je namenjen za uporabo pred pričakovano spolno aktivnostjo in ga ne priporočamo za dolgotrajno vsakodnevno uporabo.
English: ELI LILLY ČR, s.r.o.
Slovenian: Česká republika ELI LILLY ČR, s.r.o.
English: The improvement in the total international prostate symptom score with CIALIS 5mg in the four studies were -4.8, -5.6, -6.1 and -6.3 compared to -2.2,3.6, -3.8 and -4.2 with placebo.
Slovenian: -4,8, -5,6, -6,1 in -6,3 v primerjavi z -2,2, -3,6, -3,8 in -4,2 s placebom.
English: Myocardial infarction, Unstable angina pectoris2, Ventricular arrhythmia2
Slovenian: tahikardija, palpitacije miokardni infarkt, nestabilna angina pektoris2, prekatna aritmija2
English: As a precautionary measure, it is preferable to avoid the use of CIALIS during pregnancy.
Slovenian: Med nosečnostjo odsvetujemo uporabo zdravila CIALIS.
English: Men with renal impairment
Slovenian: Moški z okvaro ledvic
English: Blurred vision, Sensations described as eye pain
Slovenian: Očesne bolezni zamegljen vid, občutki opisani kot bolečina v očeh izpad v vidnem polju,
English: When taken once a day CIALIS allows you to obtain an erection, when sexually stimulated, at any time point during the 24 hours of the day.
Slovenian: Jemanje zdravila CIALIS enkrat na dan vam bo ob spolni stimulaciji omogočilo doseganje erekcije, kadarkoli tekom 24 ur dneva.
English: A selective inhibitor of CYP3A4, ketoconazole (200 mg daily), increased tadalafil (10 mg) exposure (AUC) 2-fold and Cmax by 15 %, relative to the AUC and Cmax values for tadalafil alone.
Slovenian: Selektivni zaviralec CYP3A4, ketokonazol (200 mg na dan) je povečal izpostavljenost (AUC) tadalafilu (10-mg) za 2-krat in Cmax za 15 % glede na vrednosti AUC in Cmax za sam tadalafil.
English: There are no available data about the administration of once-a-day dosing of tadalafil to patients with hepatic impairment.
Slovenian: Podatkov o dajanju odmerkov tadalafila enkrat na dan bolnikom z okvaro jeter ni.
English: Treatment of erectile dysfunction in adult males.
Slovenian: Zdravljenje erektilne disfunkcije pri odraslih moških.
English: MARKETING AUTHORISATION HOLDER Eli Lilly Nederland B.V.
Slovenian: IMETNIK DOVOLJENJA ZA PROMET Eli Lilly Nederland B.V.
English: Tadalafil has no effect in the treatment of erectile dysfunction in the absence of sexual stimulation.
Slovenian: Tadalafil pri zdravljenju erektilne disfunkcije brez spolne stimulacije nima učinka.
English: In the primary efficacy studies, 75 % of intercourse attempts were successful in CIALIS treated patients as compared to 32 % with placebo.
Slovenian: V primarnih študijah učinkovitosti je bilo pri bolnikih, zdravljenih z zdravilom CIALIS, uspešnih 75 % poskusov spolnega odnosa v primerjavi z 32 % pri placebu.
English: Serious cardiovascular events, including myocardial infarction, sudden cardiac death, unstable angina pectoris, ventricular arrhythmia, stroke, transient ischemic attacks, chest pain, palpitations and tachycardia, have been reported either post marketing and/or in clinical trials.
Slovenian: Srčnožilni dogodki V obdobju trženja zdravila in/ali kliničnih preskušanj so bili opisani resni srčnožilni dogodki, vključno z miokardnim infarktom, nenadno srčno smrtjo, nestabilno angino pektoris, ventrikularno aritmijo, možgansko kapjo, tranzitorno ishemično atako, bolečinami v prsnem košu, palpitacijami in tahikardijo.
English: NN:
Slovenian: Ti vključujejo:
English: Tadalafil (20 mg) did not augment the mean blood pressure decrease produced by alcohol (0.7 g/kg or approximately 180 ml of 40 % alcohol [vodka] in an 80-kg male) but in some subjects, postural dizziness and orthostatic hypotension were observed.
Slovenian: Tadalafil (20 mg) ni povečal povprečnega znižanja krvnega tlaka, ki ga je povzročil alkohol (0,7 g/kg ali približno 180 ml
English: CIALIS 10 mg and 20 mg is intended for use prior to anticipated sexual activity and is not recommended for continuous daily use.
Slovenian: Zdravilo CIALIS 10 mg in 20 mg je namenjeno za uporabo pred pričakovano spolno aktivnostjo in ga ne priporočamo za dolgotrajno vsakodnevno uporabo.
English: Film-coat: lactose monohydrate, hypromellose, triacetin, titanium dioxide (E171), iron oxide yellow (E172), iron oxide red (E172), talc.
Slovenian: Filmska obloga: laktoza monohidrat, hipromeloza, triacetin, titanov dioksid (E171), rumeni železov oksid (E172), rdeči železov oksid (E172), smukec.
English: Anti-hypertensives (including calcium channel blockers) The co-administration of doxazosin (4 and 8 mg daily) and tadalafil (5 mg daily dose and 20 mg as a single dose) increases the blood pressure-lowering effect of this alpha-blocker in a significant manner.
Slovenian: Sočasno jemanje doksazosina (4 mg in 8 mg na dan) in tadalafila (dnevni odmerek 5 mg in enkratni odmerek 20 mg) signifikantno okrepi hipotenzivni učinek antagonista adrenergičnih receptorjev alfa.
English: A slightly higher incidence of ECG abnormalities, primarily sinus bradycardia, has been reported in patients treated with tadalafil once a day as compared with placebo.
Slovenian: Pri bolnikih, ki so bili zdravljeni s tadalafilom z odmerjanjem enkrat na dan, so v primerjavi s placebom poročali o nekoliko povečani incidenci nepravilnosti EKG-ja, zlasti sinusni bradikardiji.
English: The mean persubject proportion of successful sexual intercourse attempts was 68 % for CIALIS patients compared to 52 % for patients on placebo.
Slovenian: Pri bolnikih, ki so jemali zdravilo CIALIS, je bilo v povprečju uspešnih 68 % poskusov spolnega odnosa, v primerjavi z 52 % pri bolnikih, ki so jemali placebo.
English: The most commonly reported adverse reactions in patients taking CIALIS for the treatment of erectile dysfunction or benign prostatic hyperplasia were headache, dyspepsia, back pain and myalgia, in which the incidences increase with increasing dose of CIALIS.
Slovenian: Neželeni učinki, o katerih so pri bolnikih, ki so jemali zdravilo CIALIS za zdravljenje erektilne disfunkcije ali benigne hiperplazije prostate, najpogosteje poročali, so bili glavobol, dispepsija,
English: Adult men
Slovenian: Odmerjanje Odrasli moški