FrancophonIA/ELRC3.0 huggingface dataset:
English: • Topical gastro-intestinal medicinal products, antacids and activated carbon, as well as colestyramine, due to reduction of the intestinal absorption of dexamethasone.
Slovenian: • zdravila za lokalno zdravljenje bolezni prebavil, antacidi in aktivno oglje ter tudi holestiramin, saj se zmanjša absorpcija deksametazona v prebavilih.
English: • Lapatinib, due to increased hepatotoxicity of lapatinib likely due to induction of CYP3A4 metabolism.
Slovenian: • lapatinib, saj se poveča hepatotoksičnost lapatiniba, kar je verjetno posledica indukcije presnove s CYP3A4;
English: • Oral anticoagulants, due to a possible impact of corticosteroids on the metabolism of the oral anticoagulant and on coagulation factors, as well as the haemorrhagic risk (mucosa of the digestive tract, vascular fragility) of dexamethasone therapy itself at high doses or treatment periods above 10 days.
Slovenian: • peroralni antikoagulanti, saj lahko kortikosteroidi vplivajo na presnovo peroralnih antikoagulantov in dejavnike strjevanja krvi, poleg tega pa lahko že deksametazon sam v velikih odmerkih ali pri zdravljenju, ki traja več kot 10 dni, povzroči tveganje za krvavitve (krvavitve iz sluznice prebavil, krhkost žil).
English: If you stop taking Neofordex
Slovenian: Če ste prenehali jemati zdravilo Neofordex
English: Repeated, daily administration of dexamethasone also leads to reduced dexamethasone plasma levels due to the induction of CYP3A4 and P-gp.
Slovenian: Pri večkratni, vsakodnevni uporabi deksametazona pride tudi do zmanjšanja koncentracije deksametazona v plazmi zaradi indukcije CYP3A4 in P-gp.
English: − Muscle cramps, muscle weakness;
Slovenian: − mišični krči, mišična šibkost;
English: The posology of anti-diabetic medicinal products may have to be adjusted during and after the treatment with dexamethasone.
Slovenian: Odmerjanje antidiabetičnih zdravil bo med zdravljenjem z deksametazonom in po njem morda treba prilagoditi;
English: The following combinations should be avoided due to safety concerns:
Slovenian: Farmakodinamične interakcije Iz varnostnih razlogov se je treba izogibati naslednjim kombinacijam:
English: Dexamethasone is metabolized via cytochrome P450 3A4 (CYP3A4).
Slovenian: Deksametazon se presnavlja s citokromom P450 3A4 (CYP3A4).
English: Concomitant administration of dexamethasone with inducers or inhibitors of CYP3A4 or P-gp may lead to decreased or increased plasma concentrations of dexamethasone, respectively.
Slovenian: Sočasna uporaba deksametazona z induktorji ali zaviralci CYP3A4 ali P-gp lahko povzroči zmanjšane ali povečane koncentracije deksametazona v plazmi.
English: − Medicinal products that may increase dexamethasone plasma concentration:
Slovenian: − zdravila, ki lahko povečajo koncentracijo deksametazona v plazmi:
English: • With digitalis, as hypokalaemia enhances the toxic effects of digitalis.
Slovenian: • z naprstcem, saj hipokaliemija okrepi njegove toksične učinke.
English: If affected, patients should be instructed not to drive, use machines or perform hazardous tasks while being treated with dexamethasone.
Slovenian: Bolnike s temi simptomi je treba opozoriti, da med zdravljenjem z deksametazonom ne smejo voziti, upravljati s stroji ali opravljati nevarnih dejavnosti.
English: Each carton contains 10 x 1 tablets in OPA/Aluminium /PVC-Aluminium perforated unit dose blister.
Slovenian: Ena škatla vsebuje 10 x 1 tableto v perforiranem pretisnem omotu za enkratni odmerek iz OPA/aluminija/PVC-aluminija.
English: − if you have a viral infection, especially viral hepatitis, herpes, chickenpox or shingles,
Slovenian: − če imate virusno okužbo, zlasti virusni hepatitis, herpes, norice ali pasovec;
English: • Isoniazid, as glucocorticoids may decrease isoniazid plasma concentrations, probably due to a stimulation of hepatic metabolism of isoniazid and a reduction of glucocorticoid metabolism.
Slovenian: • izoniazid, saj lahko glukokortikoidi zmanjšajo koncentracijo izoniazida v plazmi, kar je verjetno posledica spodbujanja jetrne presnove izoniazida in zmanjšanja presnove glukokortikoidov;
English: • Erythromycin, due to increased metabolism of erythromycin in non-carriers of the CYP3A5*1 allele after dexamethasone treatment.
Slovenian: • eritromicin, saj se po zdravljenju z deksametazonom pri tistih, ki niso prenašalci alela CYP3A5*1, poveča presnova eritromicina;
English: This may include headache, problems with your vision (including pain or swelling in the eye), feeling or being sick, fever, pain in your muscles and joints, swelling in the inside of your nose, weight loss, itchy skin and conjunctivitis.
Slovenian: Med njimi so glavobol, težave z vidom (vključno z bolečino v očesu in otekanjem očesa), slabost ali bruhanje, zvišana telesna temperatura, bolečina v mišicah in sklepih, otekline v nosu, zmanjšanje telesne mase, srbeča koža in konjunktivitis.
English: Treatment with this medicine may cause central serous chorioretinopathy, an eye disease that leads to blurred or distorted vision.
Slovenian: Zdravljenje s tem zdravilom lahko povzroči centralno serozno horioretinopatijo, očesno bolezen, ki povzroča zamegljen in popačen vid. Do tega običajno pride v enem očesu.
English: − Medicinal products that may reduce dexamethasone plasma concentration:
Slovenian: − zdravila, ki lahko zmanjšajo koncentracijo deksametazona v plazmi:
English: Neutropenia was the most frequently reported Grade 3 or 4 haematological adverse reaction in patients with relapsed/refractory multiple myeloma treated with the combination of dexamethasone with pomalidomide.
Slovenian: Nevtropenija je bila najpogosteje poročani hematološki neželeni učinek 3. ali 4. stopnje pri bolnikih z recidivnim ali proti zdravljenju odpornim multiplim mielomom, zdravljenih s kombinacijo deksametazona in pomalidomida.
English: Concomitant administration of erythropoietic medicinal products may also increase thrombotic risk in these patients.
Slovenian: Trombotično tveganje pri teh bolnikih se lahko poveča tudi zaradi sočasne uporabe eritropoetičnih zdravil.
English: Use of corticosteroids requires appropriate monitoring in patients with ulcerative colitis (due to perforation risk), recent intestinal anastomoses, diverticulitis, recent myocardial infarction (risk of left ventricular free wall rupture), diabetes mellitus (or family history), renal insufficiency, hepatic impairment, osteoporosis and myasthenia gravis.
Slovenian: Med uporabo kortikosteroidov je treba ustrezno spremljati bolnike z ulceroznim kolitisom (zaradi tveganja za predrtje), nedavnimi anastomozami črevesja, divertikulitisom, nedavnim srčnim infarktom (tveganje za rupturo proste stene levega prekata), sladkorno boleznijo (ali družinsko anamnezo te bolezni), ledvično insuficienco, okvaro jeter, osteoporozo in miastenijo gravis.
English: Effects of other medicinal products on dexamethasone Dexamethasone is metabolized via cytochrome P450 3A4 (CYP3A4), and transported by the P-glycoprotein (P-gp, also known as MDR1).
Slovenian: Deksametazon se presnavlja s citokromom P450 3A4 (CYP3A4), prenaša pa s P-glikoproteinom (P-gp, znan tudi kot MDR1).
English: Common: Liver function tests abnormal, alanine aminotransferase increased.
Slovenian: Bolezni jeter, žolčnika in žolčevodov pogosti: nenormalni izvidi preiskav delovanja jeter, povišana vrednost alanin-aminotransferaze.
English: Neofordex is a high-dose glucocorticoid.
Slovenian: Zdravilo Neofordex je visokoodmerni glukokortikoid.
English: Neofordex is a medicine that contains the active substance dexamethasone.
Slovenian: Neofordex je zdravilo, ki vsebuje učinkovino deksametazon.
English: Treatment for active gastric or duodenal ulceration should be commenced prior to initiation of corticosteroids.
Slovenian: Pred začetkom uporabe kortikosteroidov je treba uvesti zdravljenje za aktivno razjedo želodca ali dvanajstnika.
English: • With non-steroidal anti-inflammatory drugs (NSAIDs), due to an increased risk of gastrointestinal ulceration.
Slovenian: • z nesteroidnimi protivnetnimi zdravili (NSAID), saj se poveča tveganje za predrtje prebavil;
English: Tendonitis
Slovenian: Tendinitis
English: Other medicines and Neofordex Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Slovenian: Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo.
English: When Neofordex is given in combination with other medicinal products, refer to their Summaries of Product Characteristics for additional contraindications.
Slovenian: Če se bo zdravilo Neofordex uporabljalo v kombinaciji z drugimi zdravili, glejte njihove povzetke glavnih značilnosti zdravila za dodatne kontraindikacije.
English: Immunocompromised patients who have not previously had chickenpox or measles are particularly at risk.
Slovenian: Predvsem so v nevarnosti bolniki z oslabljenim imunskim sistemom, ki še niso imeli noric ali ošpic.
English: Neutropenia occurred in 45.3% of relapsed and refractory multiple myeloma patients who received low dose dexamethasone plus pomalidomide (Pom + LD-Dex), and in 19.5% of patients who received high dose dexamethasone (HD-Dex).
Slovenian: Nevtropenija se je pojavila pri 45,3 % bolnikov z recidivnim ali proti zdravljenju odpornim multiplim mielomom, ki so prejemali deksametazon v majhnem odmerku plus pomalidomid (Pom + LD-dex), ter pri 19,5 % bolnikov, ki so prejemali velik odmerek deksametazona (HD-dex).
English: The combination of lenalidomide, thalidomide or pomalidomide with dexamethasone is associated with an increased risk of deep vein thrombosis and pulmonary embolism in patients with multiple myeloma (see section 4.5).
Slovenian: Kombinacija lenalidomida, talidomida ali pomalidomida in deksametazona je pri bolnikih z multiplim mielomom povezana s povečanim tveganjem za globoko vensko trombozo in pljučno embolijo (glejte poglavje 4.5).
English: Do not take Neofordex
Slovenian: Ne jemljite zdravila Neofordex
English: 10 x 1 tablets in OPA/Aluminium /PVC-Aluminium perforated unit dose blister.
Slovenian: 10 x 1 tableta v perforiranem pretisnem omotu za enkratni odmerek iz OPA/aluminija/PVC-aluminija.
English: Patients must avoid contact with subjects with chickenpox or measles.
Slovenian: Zato se morajo bolniki izogibati stiku z osebami, ki imajo norice ali ošpice.
English: Other cytochrome P450 isoenzymes may also play a role in dexamethasone biotransformation.
Slovenian: Pri biotransformaciji deksametazona lahko sodelujejo tudi drugi izoencimi citokroma P450.
English: How to take Neofordex 4.
Slovenian: Kako jemati zdravilo Neofordex 4.
English: A similar incidence of high-grade neutropenia was reported in newly diagnosed patients treated with the combination of lenalidomide and dexamethasone.
Slovenian: O podobni incidenci nevtropenije visoke stopnje so poročali tudi pri bolnikih z na novo diagnosticirano boleznijo, ki so prejemali kombinacijo lenalidomida in deksametazona.
English: • Docetaxel and cyclophosphamide, due to reduction of their plasma levels by induction of CYP3A and P-gp.
Slovenian: • docetaksel in ciklofosfamid, saj se zaradi indukcije CYP3A in P-gp zmanjšajo njune koncentracije v plazmi;
English: Glucocorticoids have only weak acute toxicity.
Slovenian: Akutna toksičnost glukokortikoidov je majhna.
English: During treatment, a diet low in simple sugars and high in protein should be followed due to the hyperglycaemic effect of corticosteroids and their stimulation of protein catabolism with a negative nitrogen balance.
Slovenian: Kortikosteroidi delujejo hiperglikemično in spodbujajo razgradnjo beljakovin, kar povzroči negativno ravnovesje dušika, zato je med zdravljenjem treba uživati hrano z nizko vsebnostjo enostavnih sladkorjev in z visoko vsebnostjo beljakovin.
English: Neofordex will be given with other medicines for multiple myeloma.
Slovenian: Zdravilo Neofordex se uporablja skupaj z drugimi zdravili za multipli mielom.
English: In combination with thalidomide or its analogues the most serious adverse reactions were venous thromboembolic events, predominantly deep vein thrombosis and pulmonary embolism, and myelosuppression, particularly neutropenia and thrombocytopenia (see section 4.4).
Slovenian: Najresnejši neželeni učinki pri zdravljenju v kombinaciji s talidomidom ali njegovimi analogi so bili venski trombembolični dogodki, med katerimi sta prevladovali globoka venska tromboza in pljučna embolija, ter mielosupresija, zlasti nevtropenija in trombocitopenija (glejte poglavje 4.4).
English: Uncommon: Urticaria;
Slovenian: − odpoved ledvic;
English: In one study, 10.7% of patients treated with thalidomide and dexamethasone experienced grade 3/4 neuropathic reactions, compared to 0.9% of patients treated with dexamethasone alone.
Slovenian: stopnje pri 10,7 % bolnikov, zdravljenih s talidomidom in deksametazonom, v primerjavi z 0,9 % bolnikov, ki so jih zdravili samo z deksametazonom.
English: Each tablet contains dexamethasone acetate equivalent to 40 mg dexamethasone.
Slovenian: Ena tableta vsebuje deksametazonacetat v količini, ki ustreza 40 mg deksametazona.
English: Neutropenia was Grade 3 or 4 in 41.7% of patients who received Pom + LD-Dex, compared with 14.8% who received HD-Dex.
Slovenian: Nevtropenija je bila 3. ali 4. stopnje pri 41,7 % bolnikov, ki so prejemali Pom + LD-dex, in pri 14,8 % bolnikov, ki so prejemali HD-dex.
English: • Ivermectin, due to a reduction of ivermectin plasma levels.
Slovenian: • ivermektin, saj se zmanjša koncentracija ivermektina v plazmi.
English: Low-grade peripheral neuropathic reactions, predominantly grade 1 paraesthesia, may be observed with dexamethasone alone in up to 34% of newly diagnosed multiple myeloma patients.
Slovenian: Pri uporabi samega deksametazona se lahko pri največ 34 % bolnikov z na novo diagnosticiranim multiplim mielomom pojavijo periferne nevropatije nizke stopnje, predvsem parestezija 1. stopnje.
English: (purpura);
Slovenian: − koprivnica;
English: Common: Venous thromboembolic reactions, predominantly deep vein thrombosis and pulmonary embolism, hypertension, hypotension, flushing, blood pressure increased, diastolic blood pressure decreased;
Slovenian: Žilne bolezni pogosti: venski trombembolični neželeni učinki, zlasti globoka venska tromboza in pljučna embolija, hipertenzija, hipotenzija, zardevanje, zvišan krvni tlak, znižan diastolični krvni tlak; neznana pogostnost: purpura, podplutbe.
English: Thrombocytopenia occurred in 27.0% of relapsed and refractory multiple myeloma patients who received Pom + LD-Dex, and 26.8% of patients who received HD-Dex.
Slovenian: Trombocitopenija se je pojavila pri 27,0 % bolnikov z recidivnim ali proti zdravljenju odpornim multiplim mielomom, ki so prejemali Pom + LD-dex, in pri 26,8 % bolnikov, ki so prejemali HD-dex.
English: A similar incidence of high-grade thrombocytopenia was reported in newly diagnosed patients treated with the combination of lenalidomide and dexamethasone.
Slovenian: O podobni incidenci trombocitopenije visoke stopnje so poročali tudi pri bolnikih z na novo diagnosticirano boleznijo, ki so prejemali kombinacijo lenalidomida in deksametazona.
English: Common: may affect up to 1 in 10 people
Slovenian: Pogosti: pojavijo se lahko pri največ 1 od 10 bolnikov:
English: Hyperglycaemia, insomnia, muscle pain and weakness, asthenia, fatigue, oedema and weight increase occur very commonly.
Slovenian: Zelo pogosto se pojavijo hiperglikemija, nespečnost, bolečine v mišicah in šibkost mišic, astenija, utrujenost, edem in povečanje telesne mase.
English: − Reduction in the number of red or white blood cells and/or platelets, or increased number of white blood cells, decreased levels of potassium or of albumin (a protein) in the blood, increased levels of uric acid in the blood, changes in liver function tests;
Slovenian: − zmanjšanje števila rdečih in belih krvnih celic in/ali trombocitov ali povečanje števila belih krvnih celic,
English: Children do not develop multiple myeloma.
Slovenian: Otroci in mladostniki Multipli mielom se ne pojavlja pri otrocih.
English: − Rash, itching, reddened skin;
Slovenian: − izpuščaj, srbenje, pordela koža;
English: Thrombocytopenia was Grade 3 or 4 in 20.7% of patients who received Pom + LD-Dex and in 24.2% who received HD-Dex.
Slovenian: Trombocitopenija je bila 3. ali 4. stopnje pri 20,7 % bolnikov, ki so prejemali Pom + LD-dex, in pri 24,2 % bolnikov, ki so prejemali HD-dex.
English: In addition, convulsions have been reported with concurrent use of dexamethasone and ciclosporin.
Slovenian: Poleg tega so pri sočasni uporabi deksametazona in ciklosporina poročali o konvulzijah.
English: A complete blood cell count, including white blood cell count with differential count, platelet count, haemoglobin, and haematocrit should be performed at baseline, every week for the first 8 weeks of dexamethasone/lenalidomide treatment and monthly thereafter to monitor for cytopenias.
Slovenian: Pojav morebitnih citopenij je treba spremljati tako, da se ob začetku zdravljenja z deksametazonom/lenalidomidom in nato enkrat na teden prvih 8 tednov ter kasneje vsak mesec pregleda celotna krvna slika, vključno s številom belih krvnih celic skupaj z diferencialno krvno sliko, številom trombocitov, hemoglobinom in hematokritom.
English: − Vomiting, nausea, diarrhoea, indigestion, bloating, swollen and/or painful stomach;
Slovenian: − bruhanje, slabost, driska, prebavne motnje, napenjanje, napihnjen in/ali boleč želodec;
English: What Neofordex contains - The active substance is dexamethasone.
Slovenian: Kaj vsebuje zdravilo Neofordex - Učinkovina je deksametazon.
English: Neofordex administration should follow instructions for dexamethasone administration when described in the Summary of Product Characteristics of the associated treatment(s).
Slovenian: Pri uporabi zdravila Neofordex je treba upoštevati navodila za uporabo deksametazona, ki so opisana v povzetkih glavnih značilnosti zdravila za zdravila v kombinaciji.
English: Psychiatric disorders
Slovenian: Duševne motnje
English: • Praziquantel, due to the reduction of praziquantel plasma concentrations due to an increase of its hepatic metabolism by dexamethasone, with a risk of failure of treatment.
Slovenian: • prazikvantel, saj deksametazon poveča jetrno presnovo prazikvantela, zaradi česar se zmanjša njegova koncentracija v plazmi in se pojavi tveganje za neuspešno zdravljenje.
English: neofordex UNIQUE IDENTIFIER - 2D BARCODE
Slovenian: EDINSTVENA OZNAKA - DVODIMENZIONALNA ČRTNA KODA
English: You must read the package leaflets of all medicinal products to be taken in combination with Neofordex for information related to these medicines before starting treatment with Neofordex.
Slovenian: Pred začetkom jemanja zdravila Neofordex morate za informacije, povezane z zdravili, ki jih boste jemali v kombinaciji z zdravilom Neofordex, prebrati navodila za uporabo za vsa ta zdravila.
English: Prior to the use of Neofordex in combination with any other medicinal product, reference should be made to the Summary of Product Characteristics of that product.
Slovenian: Pred uporabo zdravila Neofordex v kombinaciji s katerim koli drugim zdravilom je treba prebrati povzetek glavnih značilnosti zdravila za izbrano zdravilo.
English: How to store Neofordex 6.
Slovenian: Shranjevanje zdravila Neofordex 6.
English: Common: Depression, anxiety, aggression, confusional state, irritability, nervousness, mood alteration, agitation, euphoric mood; Uncommon: Mood swings, hallucinations;
Slovenian: Duševne motnje zelo pogosti: nespečnost; pogosti: depresija, tesnoba, agresija, zmedenost, razdražljivost, živčnost, spremembe razpoloženja, agitacija, evforično razpoloženje; občasni: nihanja razpoloženja, halucinacije; neznana pogostnost: manija, psihoza, vedenjske motnje.
English: Grade 4 febrile neutropenia episodes were observed infrequently (0.6% in lenalidomide/dexamethasone-treated patients compared to 0.0% in placebo/dexamethasone treated patients).
Slovenian: Epizode febrilne nevtropenije 4. stopnje so opazili redko (0,6 % pri bolnikih, ki so prejemali lenalidomid/deksametazon, v primerjavi z 0,0 % pri bolnikih, ki so prejemali placebo/deksametazon).
English: • Ciclosporin, due to a reduction of ciclosporin bioavailability and plasma levels.
Slovenian: • ciklosporin, saj se zmanjšata biološka uporabnost in plazemska koncentracija ciklosporina.
English: Neofordex contains lactose.
Slovenian: Zdravilo Neofordex vsebuje laktozo.
English: In patients with multiple myeloma, the combination of dexamethasone with thalidomide and its analogues is associated with an increased risk of venous thromboembolism (predominantly deep vein thrombosis and pulmonary embolism) and arterial thromboembolism (predominantly myocardial infarction and cerebrovascular event) (see sections 4.5 and 4.8).
Slovenian: Kombinacija deksametazona in talidomida ter njegovih analogov lahko pri bolnikih z multiplim mielomom poveča tveganje za vensko trombembolijo (predvsem za globoko vensko trombozo in pljučno embolijo) ter arterijsko trombembolijo (predvsem za srčni infarkt in cerebrovaskularne dogodke) (glejte poglavji 4.5 in
English: − Pain, fever, chills, fainting, vertigo, exhaustion, drowsiness, impaired sense of balance.
Slovenian: − bolečine, zvišana telesna temperatura, mrzlica, omedlevica, vrtoglavica, izčrpanost, zaspanost, motnje ravnotežja;
English: Grade 4 febrile neutropenia episodes were observed infrequently (0.6% in lenalidomide/dexamethasone-treated patients compared to 0.0% in placebo/dexamethasone treated patients; see section 4.8).
Slovenian: Epizode febrilne nevtropenije 4. stopnje so opazili redko (0,6 % pri bolnikih, ki so prejemali lenalidomid/deksametazon, in 0,0 % pri bolnikih, ki so prejemali placebo/deksametazon; glejte poglavje 4.8).
English: Thrombocytopenia was also reported very commonly by patients with relapsed/refractory multiple myeloma treated with the combination of dexamethasone with pomalidomide.
Slovenian: O trombocitopeniji so zelo pogosto poročali tudi bolniki z recidivnim ali proti zdravljenju odpornim multiplim mielomom, zdravljeni s kombinacijo deksametazona in pomalidomida.
English: Depending on the duration of treatment, calcium metabolism may be impaired.
Slovenian: Med dolgotrajnejšim zdravljenjem se lahko zmanjša presnova kalcija.
English: Reference should be made to all the relevant Summary of Product Characteristics prior to the commencement of any combination treatment for additional information.
Slovenian: Pred uvedbo zdravljenja s katero koli kombinacijo je treba za več informacij prebrati vse zadevne povzetke glavnih značilnosti zdravil.
English: Dexamethasone is a type of hormone called a glucocorticoid, sometimes called a corticoid or corticosteroid, with various actions including effects on white blood cells, which form part of the immune system (the body's natural defences).
Slovenian: Deluje na različne načine, med drugim vpliva na bele krvne celice, ki so del imunskega sistema (naravne telesne obrambe).
English: You may experience serious side effects if you stop taking this medicine suddenly.
Slovenian: Nenadno prenehanje jemanja tega zdravila lahko povzroči resne neželene učinke.
English: Common: Pneumonia, herpes zoster, upper respiratory tract infection, lower respiratory tract infection, oral candidiasis, oral fungal infection, urinary tract infection, herpes simplex, candidal infection;
Slovenian: Infekcijske in parazitske bolezni pogosti: pljučnica, herpes zoster, okužba zgornjih dihal, okužba spodnjih dihal, ustna kandidoza, glivična okužba ust, okužba sečil, herpes simpleks, okužba s kandido; neznana pogostnost: okužba, sepsa.
English: Common: Weight decreased, weight increased.
Slovenian: Preiskave pogosti: zmanjšanje telesne mase, povečanje telesne mase.
English: Common: Peripheral neuropathy, dizziness, psychomotor hyperactivity, disturbance in attention, memory impairment, tremor, paraesthesia, headache, ageusia, dysgeusia, somnolence, lethargy, balance impaired, dysphonia;
Slovenian: Bolezni živčevja pogosti: periferna nevropatija, omotica, psihomotorna hiperaktivnost, motnje pozornosti, oslabljen spomin, tremor, parestezija, glavobol, agevzija, disgevzija, somnolenca, letargija, motnje ravnotežja, disfonija; občasni: cerebrovaskularni inzult, prehodni ishemični napad, amnezija, motnje koordinacije, ataksija, sinkopa; neznana pogostnost: konvulzije.