FrancophonIA/ELRC3.0 huggingface dataset:
English: ↑ cyclosporine AUC 1.66 (1.51, 1.82) Cmax 1.08 (0.97, 1.19) (CYP3A inhibition)
Croatian: ↑ ciklosporin AUC 1,66 (1,51; 1,82) Cmax 1,08 (0,97; 1,19)
English: (CYP2C9 induction)
Croatian: (indukcija CYP2C9)
English: Name and address of the manufacturer(s) responsible for batch release Schering-Plough Labo NV
Croatian: Naziv i adresa proizvođača odgovornog(ih) za puštanje serije lijeka u promet
English: Outer carton for 240 mg concentrate for solution for infusion
Croatian: Kutija za 240 mg koncentrat za otopinu za infuziju
English: PREVYMIS 240 mg sterile concentrate letermovir
Croatian: 240 mg sterilni koncentrat letermovir
English: Vial label for 480 mg concentrate for solution for infusion
Croatian: Naljepnica bočice za 480 mg koncentrat za otopinu za infuziju
English: Vial label for 240 mg concentrate for solution for infusion
Croatian: Naljepnica bočice za 240 mg koncentrat za otopinu za infuziju
English: Lactose monohydrate
Croatian: hidrokortizonnatrij sukcinat
English: The mean apparent terminal half-life for letermovir is approximately 12 hours with 480 mg IV letermovir in healthy subjects.
Croatian: Kod primjene letermovira zdravim ispitanicima u dozi od 480 mg i.v., srednja vrijednost prividnog terminalnog poluvijeka letermovira iznosi približno 12 sati.
English: Outer carton for 480 mg concentrate for solution for infusion
Croatian: Kutija za 480 mg koncentrat za otopinu za infuziju
English: How to store PREVYMIS
Croatian: Kako čuvati PREVYMIS
English: PREVYMIS 480 mg film-coated tablets letermovir
Croatian: PREVYMIS 480 mg filmom obložene tablete letermovir
English: • Potassium phosphate
Croatian: • doripenem kalijev fosfat
English: If you are breast-feeding or are planning to breast-feed, tell your doctor before taking this medicine.
Croatian: Ako dojite ili planirate dojiti, obratite se svom liječniku prije nego što uzmete ovaj lijek.
English: Once diluted, the solution of PREVYMIS is clear, and ranges from colourless to yellow.
Croatian: Otopina lijeka PREVYMIS je nakon razrjeđivanja bistra te bezbojna do žuta.
English: PREVYMIS is not recommended in pregnancy.
Croatian: Ne preporučuje se primjena lijeka PREVYMIS u trudnoći.
English: Nafcillin may decrease plasma concentrations of letermovir.
Croatian: Nafcilin može sniziti koncentracije letermovira u plazmi.
English: • Telavancin
Croatian: • mučnina
English: If concomitant administration is necessary, TDM for voriconazole is recommended the first 2 weeks after initiating or ending letermovir, as well as after changing route of administration of letermovir or immunosuppressant.
Croatian: Preporučuje se praćenje tijekom prva 2 tjedna nakon uvođenja ili nakon prekida primjene letermovira, kao i nakon promjene puta primjene letermovira ili promjene imunosupresiva.
English: General disorders and administration site conditions Uncommon fatigue, oedema peripheral
Croatian: Opći poremećaji i reakcije na mjestu primjene Manje često umor, periferni edem
English: Stem Cell Source
Croatian: Izvor matičnih stanica
English: Antidiabetic medicinal products repaglinide
Croatian: Antidijabetici repaglinid
English: Bosentan may decrease plasma concentrations of letermovir.
Croatian: Bosentan može sniziti koncentracije letermovira u plazmi.
English: (OATP1B1/3 inhibition)
Croatian: (inhibicija OATP1B1/3)
English: Nevirapine may decrease plasma concentrations of letermovir.
Croatian: Nevirapin može sniziti koncentracije letermovira u plazmi.
English: Ear and labyrinth disorders Uncommon vertigo
Croatian: Poremećaji uha i labirinta Manje često vrtoglavica
English: (P-gp/UGT induction)
Croatian: (indukcija P-gp-a/UGT-a)
English: Efavirenz may decrease plasma concentrations of letermovir.
Croatian: Efavirenz može sniziti koncentracije letermovira u plazmi.
English: (600 mg single dose PO)/ letermovir (480 mg single dose PO)
Croatian: (jedna doza od 600 mg peroralno)/ letermovir (jedna doza od 480 mg peroralno)
English: Etravirine may decrease plasma concentrations of letermovir.
Croatian: Etravirin može sniziti koncentracije letermovira u plazmi.
English: Letermovir may decrease the plasma concentrations of phenytoin.
Croatian: Letermovir može sniziti koncentracije fenitoina u plazmi.
English: PREVYMIS 240 mg concentrate for solution for infusion letermovir
Croatian: 240 mg koncentrat za otopinu za infuziju letermovir
English: Frequent monitoring of sirolimus whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of sirolimus adjusted accordingly Frequent monitoring of sirolimus concentrations is recommended at initiation or discontinuation of cyclosporine coadministration with PREVYMIS.
Croatian: Potrebno je često kontrolirati koncentracije sirolimusa u punoj krvi tijekom liječenja, kada se mijenja put primjene lijeka PREVYMIS i po prestanku liječenja lijekom PREVYMIS te sukladno njima prilagoditi dozu sirolimusa
English: • Inspect vial contents for discolouration and particulate matter prior to dilution.
Croatian: • Sadržaj bočice treba prije razrjeđivanja pregledati kako bi se utvrdilo je li promijenio boju i sadrži li čestice.
English: PREVYMIS 480 mg concentrate for solution for infusion letermovir
Croatian: PREVYMIS 480 mg koncentrat za otopinu za infuziju letermovir
English: The 240 mg and 480 mg concentrate for solution for infusion is packaged in clear, glass vials.
Croatian: Koncentrat za otopinu za infuziju od 240 mg i 480 mg dolazi u prozirnim staklenim bočicama.
English: Recommendations concerning coadministration with PREVYMIS
Croatian: Preporuke za istodobnu primjenu s lijekom PREVYMIS
English: PREVYMIS is not recommended in patients with moderate hepatic impairment combined with moderate or severe renal impairment (see section 5.2).
Croatian: Istodobno oštećenje funkcije jetre i funkcije bubrega Primjena lijeka PREVYMIS ne preporučuje se u bolesnika s umjerenim oštećenjem funkcije jetre koji uz to imaju i umjereno ili teško oštećenje funkcije bubrega (vidjeti dio 5.2).
English: Thioridazine may decrease plasma concentrations of letermovir.
Croatian: Tioridazin može sniziti koncentracije letermovira u plazmi.
English: Letermovir may increase statin plasma concentrations.
Croatian: Letermovir može povisiti koncentracije statina u plazmi.
English: PREVYMIS 240 mg film-coated tablets letermovir
Croatian: 240 mg filmom obložene tablete letermovir
English: Thirty-seven percent (37%) of subjects were engrafted at baseline.
Croatian: U 37% ispitanika je na početku ispitivanja transplantat bio prihvaćen.
English: Refer to the respective prescribing information.
Croatian: Vidjeti odgovarajuće informacije o lijeku.
English: Phenytoin may decrease plasma concentrations of letermovir.
Croatian: Fenitoin može sniziti koncentracije letermovira u plazmi.
English: • Tacrolimus
Croatian: • proljev
English: Iron oxide yellow (E172) Iron oxide red (only for 480 mg tablets) (E172) Carnauba wax (E903)
Croatian: Film ovojnica laktoza hidrat hipromeloza (E464) titanijev dioksid (E171) triacetin (E1518) željezov oksid, žuti (E172) željezov oksid, crveni (samo za tablete od 480 mg) (E172) karnauba vosak (E903)
English: Expected: ↑ glyburide
Croatian: Očekivano: ↑ gliburid
English: Close clinical monitoring for respiratory depression and/or prolonged sedation should be exercised during coadministration of PREVYMIS with midazolam.
Croatian: Kod istodobne primjene lijeka PREVYMIS i midazolama potrebno je pažljivo pratiti klinički status bolesnika zbog moguće depresije disanja i/ili produljene sedacije.
English: ↔ fluconazole AUC 1.03 (0.99, 1.08) Cmax 0.95 (0.92, 0.99) ↔ letermovir AUC 1.11 (1.01, 1.23) Cmax 1.06 (0.93, 1.21)
Croatian: ↔ flukonazol AUC 1,03 (0,99; 1,08) Cmax 0,95 (0,92; 0,99)
English: Administer the entire contents of the IV
Croatian: Primijenite cijeli sadržaj infuzijske vrećice.
English: When PREVYMIS is co-administered with cyclosporine, the magnitude of the increase in plasma concentrations of CYP3A metabolised opioids may be greater.
Croatian: Koncentracije opioida u plazmi koji se metaboliziraju putem CYP3A mogle bi porasti još više kada se PREVYMIS primjenjuje istodobno s ciklosporinom.
English: Excipients
Croatian: PREVYMIS
English: Co-administration of PREVYMIS and St. John's wort is contraindicated.
Croatian: Istodobna primjena lijeka PREVYMIS i gospine trave je kontraindicirana.
English: Cardiovascular medicinal products digoxin (0.5 mg single dose)/ letermovir (240 mg twice daily)
Croatian: 0,5 mg)/letermovir (240 mg dvaput na dan)
English: • Anti-thymocyte globulin
Croatian: Antipsihotici tioridazin
English: Frequent monitoring of sirolimus whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of sirolimus adjusted accordingly Frequent monitoring of sirolimus concentrations is recommended at initiation or discontinuation of cyclosporine co administration with PREVYMIS.
Croatian: Preporučuje se često kontrolirati koncentracije sirolimusa pri uvođenju ili prekidu istodobne primjene ciklosporina i lijeka PREVYMIS.
English: --¹ not less than 10E6.0 CCID50
Croatian: Ne manje od 10E6.0 CCID50
English: 1 glass container + 1 oral applicator + 1 transfer adapter
Croatian: 1 stakleni spremnik+ 1 oralni aplikator + 1 nastavak za prijenos
English: 1 squeezable tube multi-monodose (5 single dose) squeezable tube (polyethylene) presentation connected by a bar
Croatian: 1 oralni aplikator više jednodoznih tuba (5 pojedinačnih doza) za istiskivanje (poletilen) spojenih trakom
English: 1 oral applicator
Croatian: Zaštićeno ime
English: Therefore, patients must be monitored closely.
Croatian: Bolesnike, stoga, treba pažljivo nadzirati.
English: It will be given once a day, for up to 7 days.
Croatian: Lijek ćete dobivati jednom dnevno, do najdulje 7 dana.
English: These may be the first signs that a severe allergic reaction is happening.
Croatian: To mogu biti prvi znakovi da se događa ozbiljna alergijska reakcija.
English: Date of latest renewal: 23 February 2006
Croatian: Datum posljednje obnove: 23. veljače 2006.
English: Inspect visually prior to use.
Croatian: Vizualno provjerite otopinu prije uporabe.
English: Tell your doctor immediately if you notice any of the following as you may need to stop treatment:
Croatian: Odmah recite svom liječniku ako primijetite bilo što od sljedećeg jer ćete možda morati prekinuti liječenje:
English: 1 mg corresponds to 18.2 EAU*.
Croatian: 1 mg odgovara aktivnosti od 18,2 EAU*.
English: Via Valcanello, 4 03012 Anagni (FR) Italy
Croatian: Via Valcanello, 4 03012 Anagni (FR) Italija
English: The powder is an entire or broken white to off white pellet.
Croatian: Prašak je cjelovita ili izlomljena bijela do gotovo bijela peleta.
English: Please tell your doctor if you are taking, or have recently taken, any other medicines, including medicines obtained without a prescription.
Croatian: Obavijestite svog liječnika ako uzimate ili ste nedavno uzimali bilo koje druge lijekove, uključujući i lijekove koje ste nabavili bez recepta.
English: Fasturtec is supplied as a pack of:
Croatian: Fasturtec je dostupan u pakiranju od:
English: Your treatment with Fasturtec may need to be stopped, and you may need further treatment.
Croatian: Možda će biti potrebno prekinuti Vaše liječenje lijekom Fasturtec i možda ćete trebati daljnje liječenje.
English: Dilution before infusion:
Croatian: Razrjeđivanje prije infuzije:
English: What Fasturtec looks like and contents of the pack
Croatian: Kako Fasturtec izgleda i sadržaj pakiranja
English: It is not known whether the chance of developing an allergic reaction is increased if treatment with Fasturtec is repeated.
Croatian: Nije poznato povećava li se vjerojatnost za razvoj alergijske reakcije ako se liječenje lijekom Fasturtec ponovi.
English: No filter should be used for infusion.
Croatian: Za infuziju ne treba koristiti filter.
English: - Allergy/ allergic reactions (rashes and urticaria)
Croatian: - alergija/ alergijske reakcije (osipi i urtikarija)
English: 9 SPECIAL STORAGE CONDITIONS Store in a refrigerator
Croatian: 9 POSEBNE MJERE ČUVANJA Čuvati u hladnjaku.
English: Other medicines and Fasturtec
Croatian: Drugi lijekovi i Fasturtec
English: - Convulsion**
Croatian: - konvulzije **
English: Your doctor may also test your blood to make sure that you do not develop any blood disorders.
Croatian: Liječnik Vam također može provoditi krvne pretrage kako bi se ustanovilo imate li bilo kakav poremećaj krvi.
English: Do not use this medicine if you notice that the solution is unclear and/or contains particles.
Croatian: Ovaj lijek se ne smije upotrijebiti ako primijetite da otopina nije bistra i/ili da sadrži čestice.
English: What Fasturtec is and what it is used for
Croatian: Što je Fasturtec i za što se koristi
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity and genotoxicity.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih farmakoloških ispitivanja sigurnosti primjene, toksičnosti ponovljenih doza i genotoksičnosti.
English: These are rare (may affect up to 1 in 1,000 people).
Croatian: Te su reakcije rijetke (mogu se javiti u manje od 1 na 1000 osoba).
English: - Severe hypersensitivity reactions
Croatian: - teške reakcije preosjetljivosti
English: In case of severe allergic reaction, treatment should immediately and permanently be discontinued and appropriate therapy initiated.
Croatian: U slučaju teške alergijske reakcije, mora se odmah i trajno obustaviti liječenje te započeti s odgovarajućom terapijom.
English: Frequencies are defined using the following MedDRA convention as: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Croatian: Učestalost pojavljivanja definirana je prema MedDRA klasifikaciji kao: vrlo često (≥1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: As a protein the dose for the infant is expected to be very low.
Croatian: Budući da se radi o proteinu, očekuje se da će doza koju će dojenče primiti biti vrlo mala.
English: Your dose will be calculated according to your body weight.
Croatian: Liječnik će izračunati Vašu dozu prema Vašoj tjelesnoj težini.
English: Plasma samples should immediately be prepared by centrifugation in a pre-cooled centrifuge (4°C).
Croatian: Uzorke plazme treba odmah pripremiti centrifugiranjem u prethodno ohlađenoj centrifugi (4°C).
English: Clearance is increased (ca. 35%) in children and adolescents compared to adults, resulting in a lower systemic exposure.
Croatian: Klirens je u djece i adolescenata povećan (oko 35%) u usporedbi s odraslima, što rezultira nižom sistemskom izloženošću.
English: Fasturtec is not directly effective in the treatment of these abnormalities.
Croatian: Fasturtec nije izravno djelotvoran u liječenju tih poremećaja.
English: What you need to know before you are given Fasturtec
Croatian: Što morate znati prije nego počnete primati Fasturtec
English: Blood must be collected into pre-chilled tubes containing heparin anticoagulant.
Croatian: Krv se mora prikupljati u prethodno ohlađene spremnike koji sadrže heparinski antikoagulans.
English: The most commonly reported adverse reactions were nausea, vomiting, headache, fever, and diarrhea.
Croatian: Najčešće prijavljene nuspojave bile su mučnina, povraćanje, glavobolja, vrućica i proljev.
English: Rasburicase is a protein, and therefore: 1) not expected to bind to proteins, 2) expected that metabolic degradation will follow the pathways of other proteins, i.e. peptide hydrolysis, 3) unlikely to be candidate for drug-drug interactions.
Croatian: Razburikaza je protein te se stoga: 1) ne očekuje da se veže za proteine; 2) očekuje da će se metabolička razgradnja odvijati istim putem kao i razgradnja drugih proteina, tj. hidrolizom peptida; 3) smatra da nije kandidat za interakcije s drugim lijekovima.
English: If you suddenly notice: - a swelling of the face, lips, tongue or other part of your body - a shortness of breath, wheezing or breathing problems - a rash, itching or hives
Croatian: Ako iznenada primijetite: - oticanje lica, usana, jezika ili drugih dijelova tijela - nedostatak zraka, piskanje u plućima ili otežano disanje - osip, svrbež ili koprivnjaču
English: As metabolism is expected to occur by peptide hydrolysis, an impaired liver function is not expected to affect the pharmacokinetics.
Croatian: Budući da se očekuje da se metabolizam odvija putem hidrolize peptida, ne očekuje se da bi narušena funkcija jetre utjecala na farmakokinetiku.
English: Fasturtec will be administered at the same time as other medicines that may also cause side effects.
Croatian: Fasturtec ćete dobiti u isto vrijeme kad i druge lijekove koji također mogu uzrokovati nuspojave.
English: During treatment with Fasturtec, the advantage of breastfeeding should be weighted against the potential risk for the infant.
Croatian: Tijekom liječenja lijekom Fasturtec treba odvagnuti korist od dojenja u odnosu na mogući rizik za dojenče.
English: Sanofi Chimie Route d'Avignon 30390 Aramon France
Croatian: Sanofi Chimie Route d'Avignon 30390 Aramon Francuska
English: Frequency not known (frequency cannot be estimated from the available data) - involuntary muscle movements (muscle contraction involuntary).
Croatian: Učestalost nepoznata (učestalost se ne može procijeniti iz dostupnih podataka) nevoljni mišićni pokreti (nevoljne mišićne kontrakcije).
English: The mean terminal half-life was similar between paediatric and adult patients and ranged from 15.7 to 22.5 hours.
Croatian: Prosječan terminalni poluvijek bio je podjednak u pedijatrijskih i odraslih bolesnika i kretao se od 15,7 do 22,5 sati.
English: - Bronchospasm - Rhinitis
Croatian: - bronhospazam - rinitis
English: Samples must be immersed in an ice/water bath.
Croatian: Uzorke treba uroniti u kupku s ledom/vodom.
English: - Diarrhoea + - Vomiting++ - Nausea++
Croatian: - proljev+ -povraćanje++ - mučnina++
English: Detailed information on this product is available on the website of the European Medicines Agency http://www.ema.europa.eu
Croatian: Detaljnije informacije o ovom lijeku dostupne su na web stranici Europske agencije za lijekove http://www.ema.europa.eu.
English: The recommended dose is 0.20 mg per kg of body weight per day in both children and adults.
Croatian: Preporučena doza iznosi 0,20 mg po kilogramu tjelesne težine na dan i u djece i u odraslih.
English: Pregnancy and breast-feeding Tell your doctor if you are, or think you may be pregnant, or if you are breast-feeding.
Croatian: Trudnoća i dojenje Obavijestite svog liječnika ako ste trudni, mislite da biste mogli biti trudni ili ako dojite.
English: Because teratogenic effects of rasburicase cannot be ruled out, Fasturtec should only be used during pregnancy if strictly necessary.
Croatian: S obzirom da se ne mogu isključiti teratogeni učinci razburikaze, Fasturtec se smije primjenjivati u trudnoći samo ako je to zaista neophodno.
English: Time to first confirmation of normal levels of uric acid in hyperuricaemic patients is four hours for Fasturtec and 24 hours for allopurinol.
Croatian: Vrijeme do prve potvrde normalnih vrijednosti mokraćne kiseline u hiperuricemičnih bolesnika iznosi 4 sata za Fasturtec, a 24 sata za alopurinol.
English: Fertility There are no data regarding the effect of rasburicase on fertility.
Croatian: Plodnost Nema podataka o utjecaju razburikaze na plodnost.
English: Fasturtec is to be given to you before or during the start of your course of chemotherapy.
Croatian: Fasturtec ćete primiti prije ili na početku liječenja kemoterapijom.
English: Minimal accumulation of rasburicase (<1.3 fold) was observed between days 1 and 5 of dosing.
Croatian: Opažena je minimalna kumulacija razburikaze (< 1,3 puta) između 1. i 5. dana primjene.
English: The required volume of the reconstituted solution depends on the patient's body weight.
Croatian: Potreban volumen rekonstituirane otopine ovisi o tjelesnoj težini bolesnika.
English: The safety results of patients treated with Fasturtec in Study EFC4978 were consistent with the adverse events profile observed in previous clinical studies with predominantly paediatric patients.
Croatian: Rezultati ispitivanja sigurnosti primjene u bolesnika liječenih lijekom Fasturtec u Ispitivanju EFC4978 bili su sukladni profilu nuspojava opaženom u ranijim kliničkim ispitivanjima s pretežno pedijatrijskim bolesnicima.
English: Sample handling:
Croatian: Rukovanje uzorcima:
English: Safety results on 246 patients were consistent with the adverse events profile in the overall population.
Croatian: Rezultati ispitivanja sigurnosti primjene u 246 bolesnika bili su sukladni profilu nuspojava u ukupnoj populaciji.
English: Talk to your doctor, nurse or hospital pharmacist if you have a history of any kind of allergy.
Croatian: Obavijestite svog liječnika, medicinsku sestru ili bolničkog ljekarnika ako ste imali bilo koju vrstu alergije.
English: - Hypotension
Croatian: - hipotenzija
English: - Fever++
Croatian: - vrućica++
English: Tell your doctor if you have ever had any allergic type reactions due to other medicines; Fasturtec can cause allergic-type reactions, such as severe anaphylaxis including anaphylactic shock (sudden lifethreatening or fatal allergic reactions).
Croatian: Recite liječniku ako ste ikada imali bilo kakvu alergijsku reakciju uzrokovanu drugim lijekovima; Fasturtec može izazvati alergijske reakcije, kao što je teška anafilaksija, uključujući anafilaktički šok (iznenadne životno opasne ili smrtonosne alergijske reakcije).
English: Only clear and colourless solutions without particles should be used.
Croatian: Smije se koristiti samo bistra i bezbojna otopina, bez čestica.
English: Clinical efficacy and safety
Croatian: Klinčka djelotvornosti i sigurnost
English: Therefore the reconstituted solution should be diluted under controlled and validated aseptic conditions.
Croatian: Rekonstituiranu otopinu treba, stoga, razrijediti pod kontroliranim i validiranim aseptičkim uvjetima.
English: During treatment with Fasturtec, your doctor will carry out blood tests to check the levels of uric acid and decide how long you will be treated for.
Croatian: Tijekom liječenja lijekom Fasturtec liječnik će provoditi krvne pretrage radi provjere razine mokraćne kiseline te će odlučiti koliko dugo ćete se liječiti.
English: Finally, plasma must be maintained in an ice/water bath and analysed for uric acid within 4 hours.
Croatian: Konačno, uzorke plazme treba čuvati u ledenoj/vodenoj kupki te odrediti razinu mokraćne kiseline u roku od 4 sata.
English: Fasturtec is injected slowly into a vein, which should take about 30 minutes.
Croatian: Fasturtec se polako injicira u venu, u trajanju od oko 30 minuta.
English: Efficacy results on 229 evaluable patients showed an overall response rate (normalization of plasma uric acid levels) of 96.1%.
Croatian: Rezultati ispitivanja djelotvornosti u 229 bolesnika koje se moglo ocijeniti pokazali su ukupan udio terapijskog odgovora (normalizaciju vrijednosti mokraćne kiseline u plazmi) od 96,1%.
English: Therefore the diluted solution should be infused immediately.
Croatian: Razrijeđenu otopinu treba, stoga, odmah primijeniti.
English: Tell your doctor, nurse or hospital pharmacist immediately as these may be signs of a serious allergic reaction (anaphylaxis).
Croatian: Odmah obavijestite svog liječnika, medicinsku sestru ili bolničkog ljekarnika jer to mogu biti znakovi ozbiljne alergijske reakcije (anafilaksije).
English: Rasburicase is a tetrameric protein with identical subunits of a molecular mass of about 34 kDa.
Croatian: Razburikaza je tetramerni protein s identičnim podjedinicama, molekularne mase od oko 34 kDa.