FrancophonIA/ELRC3.0 huggingface dataset:
English: This is thought to be due to differences in parental characteristics (e.g., maternal age, sperm characteristics) and the higher incidence of multiple pregnancies.
Slovenian: Menijo, da je to posledica razlik v značilnostih staršev (npr. starosti matere, značilnostih sperme) in večje incidence večplodnih nosečnosti.
English: Corifollitropin alfa does not display any intrinsic LH/hCG activity.
Slovenian: Korifolitropin alfa nima nobene intrinzične aktivnosti LH/hCG.
English: *corifollitropin alfa is a glycoprotein produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology.
Slovenian: *Korifolitropin alfa je glikoprotein, izdelan v ovarijskih celicah kitajskega hrčka (CHO) z uporabo tehnologije rekombinantne DNA.
English: In case of an excessive ovarian response, see the recommendations given in section 4.4 in order to reduce the risk for developing ovarian hyperstimulation syndrome (OHSS).
Slovenian: Če je odziv jajčnikov premočan, pa glejte priporočila, ki so podana v poglavju 4.4, da boste zmanjšali tveganje za nastanek sindroma hiperstimulacije jajčnikov (OHSS).
English: Treatment with a GnRH antagonist should be started on stimulation day 5 or day 6 depending on the ovarian response, i.e. the number and size of growing follicles.
Slovenian: Zdravljenje z antagonistom GnRH je treba začeti na 5. dan stimulacije oziroma na 6. dan, odvisno od odziva jajčnikov, tj. od števila in velikosti rastočih foliklov.
English: IVF involves collecting the eggs from the ovary, fertilising them in the laboratory, and transferring the embryos into the uterus a few days later.
Slovenian: Pri IVF zberejo jajčeca iz jajčnikov, jih oplodijo v laboratoriju in nekaj dni pozneje zarodke prenesejo v maternico.
English: For women having their first cycle of ovarian stimulation, for whom risk factors are only partially known, close observation for early signs and symptoms of OHSS is recommended.
Slovenian: Pri ženskah, ki imajo prvi ciklus stimulacije jajčnikov in so dejavniki tveganja pri njih le delno znani, pa je priporočljivo pozorno spremljanje glede zgodnjih znakov in simptomov OHSS.
English: Alanine aminotransferase increased, aspartate aminotransferase increased
Slovenian: Preiskave občasni zvišanje alanin-aminotransferaze, zvišanje aspartat-aminotransferaze
English: Do not use this medicine after the expiry date which is stated on the label and outer carton after “EXP” (expiry date).
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki in na škatli poleg oznake EXP (rok uporabnosti).
English: Results of a small uncontrolled study suggest a higher ovarian response than in combination with a GnRH antagonist.
Slovenian: Izsledki majhne nenadzorovane študije pa so pokazali večji odziv jajčnikov kot pri uporabi kombinacije z antagonistom GnRH.
English: Since corifollitropin alfa is not a substrate of cytochrome P450 enzymes, no metabolic interactions with other medicinal products are anticipated.
Slovenian: Ker pa korifolitropin alfa ni substrat za encime citokroma P450, ni pričakovati nikakršnih presnovnih interakcij z drugimi zdravili.
English: The steady state volume of distribution is 9.2 L (6.5-13.1 L
Slovenian: Porazdelitveni volumen v stanju dinamičnega ravnovesja je 9,2 l (od 6,5 do 13,1 l
English: - A single 150-microgram dose is recommended in women: who weigh more than 60 kilograms, regardless of age.
Slovenian: - Enkraten odmerek 150 mikrogramov je priporočljiv za ženske: ki tehtajo več kot 60 kilogramov, ne glede na starost.
English: The pH may have been adjusted with sodium hydroxide and/or hydrochloric acid.
Slovenian: pH je lahko bil uravnan z natrijevim hidroksidom in/ali klorovodikovo kislino.
English: Because of the risk of developing OHSS, patients should be monitored for at least two weeks after hCG administration.
Slovenian: Zaradi tveganja za nastanek OHSS je treba ženske spremljati še najmanj dva tedna po prejemu hCG.
English: 1) and a clearance of 0.13 L/h
Slovenian: 1), očistek znaša 0,13 l/h (od
English: The injection may be given by a healthcare professional (for example a nurse), your partner or yourself, if carefully instructed by your doctor.
Slovenian: Injekcijo vam bo lahko dal zdravstveni delavec (na primer medicinska sestra) ali vaš partner oziroma si jo boste dali sami, če vam je zdravnik dal natančna navodila za to.
English: OHSS may be caused by administration of hCG and by pregnancy (endogenous hCG).
Slovenian: OHSS lahko povzročita uporaba hCG in nosečnost (endogeni hCG).
English: Reproduction toxicology studies in rats and rabbits indicated that corifollitropin alfa does not adversely affect fertility.
Slovenian: Toksikološke študije razmnoževanja pri podganah in kuncih so pokazale, da korifolitropin alfa ne vpliva negativno na plodnost.
English: Not known (cannot be estimated from available data) - Allergic reactions (hypersensitivity reactions, both local and generalised, including rash).
Slovenian: Neznana pogostnost (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti) - alergijske reakcije (preobčutljivostne reakcije, tako lokalne kot generalizirane, vključno z izpuščajem).
English: Both embryotoxicity and teratogenicity are considered a consequence of the superovulatory state of the animal not able to support a number of embryos above a physiological ceiling.
Slovenian: Vendar bi tako embriotoksičnost kot teratogenost lahko šteli za posledici superovulatornega stanja živali, katerih telo ni moglo vzdrževati števila zarodkov nad fiziološko zgornjo mejo.
English: One of these gonadotropic hormones is follicle-stimulating hormone (FSH), which is needed in women for the growth and development of follicles (small round sacs in your ovaries that contain the eggs).
Slovenian: Eden od teh gonadotropnih hormonov je folikle stimulirajoči hormon (FSH), ki je pri ženskah potreben za rast in razvoj foliklov (majhnih, okroglih vrečic v jajčnikih, v katerih so jajčeca).
English: Stimulation day 5 or 6:
Slovenian: 5. ali 6. dan stimulacije:
English: In women with generally recognized risk factors for thromboembolic events, such as a personal or family history, severe obesity or thrombophilia, treatment with gonadotropins may further increase this risk.
Slovenian: Pri ženskah, ki imajo splošno priznane dejavnike tveganja za tromboembolične pojave, na primer pri tistih s tromboembolični pojavi v osebni ali družinski anamnezi, hudo debelostjo ali trombofilijo, lahko zdravljenje z gonadotropini dodatno poveča omenjeno tveganje.
English: In women undergoing ART procedures the risk of multiple pregnancy is mainly related to the number of embryos transferred.
Slovenian: Pri ženskah v programu asistirane reprodukcije je tveganje za večplodno nosečnost povezano predvsem s številom prenesenih zarodkov.
English: <Justification for not including Braille accepted>
Slovenian: <Sprejeta je utemeljitev, da Braillova pisava ni potrebna>
English: FTET Cycles of ENGAGE
Slovenian: FTET cikli študije ENGAGE
English: Multiple pregnancies and specific characteristics of couples with fertility problems (e.g., a woman's age, certain sperm problems, genetic background of both parents) may also be associated with an increased chance of birth defects.
Slovenian: Večplodne nosečnosti in posebne značilnosti parov, ki imajo težave s plodnostjo (npr. zaradi starosti ženske, določenih težav s spermo, genetske zasnove obeh staršev), so lahko povezane tudi s povečano verjetnostjo za prirojene napake pri otroku.
English: These side effects are not considered to be related to the use of Elonva, but to Assisted Reproductive Technology (ART) or subsequent pregnancy.
Slovenian: Ti neželeni učinki ne veljajo za povezane z uporabo zdravila Elonva, ampak povezane z asistirano reprodukcijo (ART) oziroma s poznejšo nosečnostjo.
English: Older than 36 years
Slovenian: Več kot 36 let
English: If you use more Elonva or (rec)FSH than you should If you think you have used more Elonva or (rec)FSH than you should, contact your doctor immediately.
Slovenian: Če ste uporabili večji odmerek zdravila Elonva ali (rek)FSH, kot bi smeli Če mislite, da ste uporabili več zdravila Elonva ali (rek)FSH, kot bi smeli, se nemudoma posvetujte z zdravnikom.
English: More than one injection of Elonva within one treatment cycle or too high a dose of Elonva and/or (rec)FSH may increase the risk of OHSS (see OHSS in section 4.4.
Slovenian: Dajanje več kot ene injekcije zdravila Elonva v posameznem ciklusu zdravljenja ali uporaba prevelikega odmerka zdravila Elonva in/ali (rek)FSH lahko povečata tveganje za OHSS (glejte OHSS v poglavju 4.4).
English: What Elonva is and what it is used for
Slovenian: Kaj je zdravilo Elonva in za kaj ga uporabljamo
English: Early OHSS usually occurs within 10 days after hCG administration and may be associated with an excessive ovarian response to gonadotropin stimulation.
Slovenian: Zgodnji OHSS običajno nastopi v 10 dneh po prejemu hCG in je lahko združen s čezmernim odzivom jajčnikov na spodbujanje z gonadotropini.
English: This leaflet was last revised in Month YYYY.
Slovenian: Navodilo je bilo nazadnje revidirano dne mesec LLLL.
English: 1) and is reached 44 hours (35-57 hours
Slovenian: 1) in je dosežena 44 ur (od 35 do 57 ur 1) po odmerku.
English: Elonva 150 µg recFSH 300 IU n N % n N % n N % n N %
Slovenian: (rek)FSH 300 i.e. n N % n N % n N % n N %
English: The recommended doses of Elonva have only been established in a treatment cycle with a GnRH antagonist that was administered from stimulation day 5 or day 6 onwards (see also sections 4.1, 4.4, and 5.1).
Slovenian: Priporočeni odmerki zdravila Elonva so bili določeni le v ciklusu zdravljenja z antagonistom GnRH, ki so ga uporabili od 5. ali 6. dne stimulacije naprej (glejte tudi poglavja 4.1, 4.4 in 5.1).
English: Distribution, metabolism and elimination of corifollitropin alfa are very similar to other gonadotropins, such as FSH, hCG and LH.
Slovenian: Po porazdelitvi, presnovi in izločanju je korifolitropin alfa zelo podoben drugim gonadotropinom, kot so FSH, hCG in LH.
English: Women older than 36 years of age who weighed less than 50 kilograms were not studied.
Slovenian: Uporabe pri ženskah, starejših od 36 let in s telesno maso manj kot 50 kilogramov, niso raziskali.
English: You should not use Elonva if you are already pregnant, or think that you might be pregnant, or if you are breast-feeding.
Slovenian: Zdravila Elonva ne smete uporabljati, če ste noseči ali menite, da bi lahko bili noseči, oziroma če dojite.
English: The incidence of congenital malformations after ART may be slightly higher than after spontaneous conceptions.
Slovenian: Incidenca kongenitalnih malformacij po asistirani reprodukciji je lahko nekoliko večja kot po spontani zanositvi.
English: If you forget to use Elonva
Slovenian: Če ste pozabili uporabiti zdravilo Elonva
English: Self administration of Elonva should only be performed by women who are well-motivated, adequately trained and with access to expert advice.
Slovenian: Zdravilo Elonva si smejo same injicirati samo tiste ženske, ki so motivirane in ustrezno usposobljene za to ter imajo dostop do nasveta strokovnjaka.
English: In each case, these antibodies were non-neutralizing and did not interfere with the response to stimulation or the normal physiologic responses of the Hypothalamic-Pituitary-Ovarian (HPO) axis.
Slovenian: Pri nobeni ženski ta telesa niso bila nevtralizirajoča in niso vplivala na odziv na stimulacijo ali na normalne fiziološke odzive hipotalamo-hipofizno-ovarijske osi.
English: Of the 2,511 women treated with Elonva who were evaluated for the formation of post-treatment antibodies, four (0.16%) had evidence of antibody formation, including three who had been exposed once to Elonva and one who had been exposed twice to Elonva.
Slovenian: Od 2.511 žensk, zdravljenih z zdravilom Elonva, pri katerih so opravili preiskave glede nastajanja protiteles po zdravljenju, so nastajanje protiteles ugotovili pri štirih (0,16 %); tri od njih so bile zdravilu Elonva izpostavljene enkrat, ena pa dvakrat.
English: Other medicines and Elonva
Slovenian: Druga zdravila in zdravilo Elonva
English: Stimulation day 8:
Slovenian: 8. dan stimulacije:
English: Pharmacokinetic parameters of corifollitropin alfa were evaluated after subcutaneous administration in women undergoing a COS treatment cycle.
Slovenian: Farmakokinetične parametre korifolitropina alfa so ocenili po subkutani uporabi pri ženskah, pri katerih je potekal ciklus zdravljenja COS.
English: This may be due to cross-reactivity of hCG pregnancy tests with the carboxy-terminal peptide of the beta subunit of Elonva.
Slovenian: To je lahko zaradi navzkrižne reaktivnosti nekaterih hCG testov nosečnosti s karboksi-terminalnim peptidom beta podenote zdravila Elonva.
English: Do not throw away an empty or unused syringe via household waste.
Slovenian: Prazne ali neporabljene injekcijske brizge ne smete odvreči med gospodinjske odpadke.
English: In particular, women should be evaluated for hypothyroidism, adrenocortical insufficiency, hyperprolactinemia and pituitary or hypothalamic tumours, and appropriate specific treatment given.
Slovenian: Še posebej je treba te ženske pregledati, da ugotovite, ali imajo hipotireozo, adrenokortikalno insuficienco, hiperprolaktinemijo in tumorje hipofize ali hipotalamusa, ter jim uvesti ustrezno specifično zdravljenje.
English: Therefore, the use of Elonva is not recommended in combination with a GnRH agonist (see also section 4.2).
Slovenian: Zato uporaba zdravila Elonva ni priporočljiva v kombinaciji z agonistom GnRH (glejte tudi poglavje 4.2).
English: Damage to the ovary due to reduced blood supply can be limited by early diagnosis and immediate detorsion.
Slovenian: Poškodba jajčnikov zaradi zmanjšane prekrvavitve se lahko omeji z zgodnjim odkritjem in takojšnjo detorzijo (odvitjem).
English: It is not known if treatment with fertility medicines increases the risk of these tumours in infertile women.
Slovenian: Ni znano, ali zdravljenje z zdravili za plodnost poveča tveganje za nastanek teh tumorjev pri neplodnih ženskah.
English: No interaction studies with Elonva and other medicines have been performed.
Slovenian: Študij medsebojnega delovanja zdravila Elonva z drugimi zdravili niso izvedli.
English: Subcutaneous injection of Elonva may be carried out by the woman herself or her partner, provided that proper instructions are given by the physician.
Slovenian: Subkutano injiciranje zdravila Elonva lahko izvede ženska sama ali pa ji zdravilo injicira njen partner, pod pogojem, da sta od zdravnika dobila ustrezna navodila.
English: Stimulation day 1:
Slovenian: 1. dan stimulacije:
English: If you feel dizzy, you should not drive or use machines.
Slovenian: Če ste omotični, ne upravljajte vozil ali strojev.
English: Storage by the pharmacist Store in a refrigerator.
Slovenian: Shranjevanje v lekarni Shranjujte v hladilniku.
English: Please discuss this with your doctor, before starting treatment, especially if: - you know you already have an increased chance of having a thrombosis - you, or anyone in your immediate family, have ever had a thrombosis - you are severely overweight.
Slovenian: O tem se morate pogovoriti z zdravnikom še pred začetkom zdravljenja, še posebej: - če veste, da imate že povečano verjetnost za nastanek tromboze, - če ste imeli vi ali kdor koli v vaši ožji družini kadar koli v življenju trombozo, - če imate močno povečano telesno maso.
English: After absorption into the blood, corifollitropin alfa is distributed mainly to the ovaries and the kidneys.
Slovenian: Po absorpciji v kri se korifolitropin alfa porazdeli predvsem v jajčnike in ledvice.
English: A step-by-step “instructions for use” is given at the end of this leaflet.
Slovenian: Podrobna navodila za dajanje zdravila so podana tudi na koncu teh navodil.
English: 36 years or younger
Slovenian: 36 let ali manj
English: The table below displays the main adverse reactions in women treated with Elonva in clinical trials and post-marketing surveillance according to system organ class and frequency; very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), and not known (cannot be estimated from available data).
Slovenian: V spodnji preglednici so podani glavni neželeni učinki pri ženskah, zdravljenih z zdravilom Elonva v kliničnih preskušanjih in v času trženja zdravila, razvrščeni po organskih sistemih in po pogostnosti; zelo pogosti (≥ 1/10), pogosti (od ≥ 1/100 do < 1/10), občasni (od ≥ 1/1.000 do < 1/100), redki (od ≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000) in neznana pogostnost (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti).
English: Corifollitropin alfa exposure after a single subcutaneous injection is 665 hours*ng/mL (AUC, 426-1,037 hours*ng/mL
Slovenian: Izpostavljenost korifolitropinu alfa po enkratni subkutani injekciji je 665 ur*ng/ml (AUC, 426-1.037 ur*ng/ml
English: After a single subcutaneous injection of Elonva, the maximum serum concentration of corifollitropin alfa is 4.24 ng/mL (2.49-7.21 ng/mL
Slovenian: Po enkratni subkutani injekciji zdravila Elonva je največja serumska koncentracija korifolitropina alfa 4,24 ng/ml (2,49-7,21 ng/ml
English: Injury, poisoning and procedural complications
Slovenian: Poškodbe, zastrupitve in zapleti postopkov občasni bolečina ob postopku
English: Do not inject Elonva without talking with your doctor.
Slovenian: Zdravila Elonva si ne injicirajte, ne da bi se posvetovali z zdravnikom.
English: The most frequently reported adverse reactions during treatment with Elonva in clinical trials (N=2,397) are pelvic discomfort (6.0%), OHSS (4.3%, see also section 4.4), headache (4.0%), pelvic pain (2.9%), nausea (2.3%), fatigue (1.5%), and breast tenderness (1.3%).
Slovenian: Najpogosteje poročani neželeni učinki med zdravljenjem z zdravilom Elonva v kliničnih preskušanjih (N = 2.397) so bili neugodje v medenici (6,0 %), OHSS (4,3 %, glejte tudi poglavje 4.4), glavobol (4,0 %), bolečine v medenici (2,9 %), slabost (2,3 %), utrujenost (1,5 %) in občutljivost dojk (1,3 %).
English: The GnRH antagonist is used to prevent premature Luteinising Hormone (LH) surges.
Slovenian: Antagonist GnRH uporabimo za preprečevanje prezgodnjega zvišanja koncentracije luteinizirajočega hormona (LH).
English: The first symptoms of ovarian overstimulation may be noticed as pain in the stomach (abdomen), feeling sick or diarrhoea.
Slovenian: Prvi simptomi hiperstimulacije jajčnikov so opazni v obliki bolečin v trebuhu (abdomnu) ter občutka slabosti ali driske.
English: The syringe is packed together with a sterile injection needle.
Slovenian: Injekcijska brizga je pakirana skupaj s sterilno injekcijsko iglo.
English: Elonva may cause a false positive hCG pregnancy test if the test is administered during the ovarian stimulation portion of the ART cycle.
Slovenian: Zdravilo Elonva lahko povzroči lažno pozitiven hCG test nosečnosti, če se test izvede med stimulacijo jajčnikov v ART ciklu.
English: If you forgot to inject Elonva on the day you should have, contact your doctor immediately.
Slovenian: Če si pozabite injicirati zdravilo Elonva na predvideni dan, se takoj posvetujte z zdravnikom.
English: In case of inadvertent exposure to Elonva during pregnancy, clinical data are not sufficient to exclude an adverse outcome of pregnancy.
Slovenian: V primeru, da je v času nosečnosti prišlo do nenamerne izpostavljenosti zdravilu Elonva, dosedanji klinični podatki niso zadostni, da bi lahko izključili neželeni izid nosečnosti.
English: Elonva contains the active ingredient corifollitropin alfa and belongs to the group of medicines called gonadotropic hormones.
Slovenian: Zdravilo Elonva vsebuje učinkovino korifolitropin alfa in spada v skupino zdravil, imenovanih gonadotropni hormoni.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with Elonva in one or more subsets of the paediatric population in hypogonadotrophic hypogonadism (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z zdravilom Elonva za vse skupine pediatrične populacije s hipogonadoptropnim hipogonadizmom (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Ovarian torsion may be related to other conditions, such as OHSS, pregnancy, previous abdominal surgery, past history of ovarian torsion, and previous or current ovarian cysts.
Slovenian: Torzija jajčnikov je lahko povezana z drugimi stanji, kot so OHSS, nosečnost, predhodne operacije trebuha, torzija jajčnikov v preteklosti in v preteklosti ali trenutno prisotne ciste jajčnikov.
English: (0.10-0.18 L/h
Slovenian: 0,10 do 0,18 l/h
English: In ART there is an increased risk of OHSS with 18 or more follicles of 11 mm or more in diameter.
Slovenian: Pri asistirani reprodukciji obstaja povečano tveganje za OHSS pri 18 ali več foliklih premera 11 mm ali več.
English: What you need to know before you use Elonva
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Elonva
English: In animal studies reproductive toxicity has been observed (see preclinical safety data in section 5.3).
Slovenian: V študijah pri živalih so opazili toksičnost oz. vpliv na sposobnost razmnoževanja (glejte predklinične podatke o varnosti v poglavju 5.3).
English: The daily dose of (rec)FSH may depend on the ovarian response.
Slovenian: Dnevni odmerek (rek)FSH je lahko odvisen od odziva jajčnikov.
English: The long duration of FSH activity was achieved by adding the carboxy-terminal peptide of the β-subunit of human chorionic gonadotropin (hCG) to the β-chain of human FSH.
Slovenian: Dolgo trajanje aktivnosti FSH je bilo doseženo z dodajanjem karboksi-terminalnega peptida β podenote humanega horionskega gonadotropina (hCG) β verigi humanega FSH.
English: OHSS is a medical event distinct from uncomplicated ovarian enlargement.
Slovenian: OHSS je medicinski sopojav, ki se razlikuje od preprostega povečanja jajčnikov brez zapletov.
English: Ectopic pregnancy
Slovenian: Ektopična nosečnost
English: Elonva is intended for single subcutaneous injection only.
Slovenian: Zdravilo Elonva je namenjeno samo za enkratno subkutano injiciranje.
English: Intravascular thrombosis, which may originate in venous or arterial vessels, can result in reduced blood flow to vital organs or the extremities.
Slovenian: Intravaskularna tromboza, ki se lahko začne v venski ali arterijski žili, lahko posledično povzroči zmanjšan krvni obtok v vitalnih organih ali okončinah.
English: Corifollitropin alfa is designed as a sustained follicle stimulant with the same pharmacodynamic profile as (rec)FSH, but with a markedly prolonged duration of FSH activity.
Slovenian: Korifolitropin alfa je dolgotrajnejši stimulant rasti foliklov in ima enak farmakodinamični profil kot (rek)FSH, vendar znatno daljše trajanje aktivnosti FSH.
English: Your doctor may also check blood hormone levels.
Slovenian: Lahko bo spremljal tudi koncentracije hormonov v krvi.
English: If you do a pregnancy test during your infertility treatment with Elonva, the test might wrongly suggest that you are pregnant.
Slovenian: Če med zdravljenjem neplodnosti z zdravilom Elonva opravite test nosečnosti, lahko test napačno pokaže, da ste noseči.
English: The primary efficacy endpoint in the ENGAGE study was ongoing pregnancy (assessed at least 10 weeks after embryo transfer).
Slovenian: Primarni opazovani dogodek učinkovitosti v študiji ENGAGE je bila potekajoča nosečnost (ocenjena vsaj 10 tednov po prenosu zarodka).
English: Exposure to corifollitropin alfa increases proportionally with dose within the range of 60 micrograms to 240 micrograms.
Slovenian: Izpostavljenost korifolitropinu alfa se v razponu odmerkov od 60 do 240 mikrogramov povečuje sorazmerno odmerku.
English: It is not established whether or not treatment with gonadotropins increases the risk of these tumours in infertile women.
Slovenian: Ni bilo ugotovljeno, ali zdravljenje z gonadotropini poveča tveganje za nastanek teh tumorjev pri neplodnih ženskah ali ne.
English: The number of oocytes retrieved was a key secondary efficacy endpoint.
Slovenian: Število dobljenih jajčec je bil ključni sekundarni opazovani dogodek učinkovitosti.