FrancophonIA/ELRC3.0 huggingface dataset:
English: • Because of a risk of breathing problems, the use of codeine medicines for pain relief in children has been restricted: these medicines are now only to be used to treat acute (short lived) moderate pain in children above 12 years of age, and only if it cannot be relieved by other painkillers such as paracetamol or ibuprofen.
Slovenian: • Zaradi tveganja za težave z dihanjem je bila uporaba zdravil za lajšanje bolečine, ki vsebujejo kodein, pri otrocih omejena: ta zdravila se lahko po novem uporabljajo samo za zdravljenje akutne (prehodne) zmerne bolečine pri otrocih, starejših od 12 let, ki je ni mogoče ublažiti z drugimi zdravili proti bolečinam, na primer s paracetamolom ali ibuprofenom.
English: Some of the children who had suffered severe side effects had evidence of being ‘ultra-rapid metabolisers' of codeine.
Slovenian: Nekateri otroci, pri katerih so se pojavili hudi neželeni učinki, so imeli znake „izredno hitre presnove kodeina.
English: • Codeine should not be used at all in children (aged below 18 years) who undergo surgery for the removal of the tonsils or adenoids to treat obstructive sleep apnoea, as these patients are more susceptible to respiratory problems.
Slovenian: • kodein se nikakor ne sme uporabljati pri otrocih (mlajših od 18 let), ki so prestali operacijo za odstranitev tonzil ali žrelnic zaradi obstruktivne apneje med spanjem, saj so ti bolniki dovzetnejši za težave z dihanjem;
English: Some of the children were found to be CYP2D6 ultra-rapid metabolisers.
Slovenian: Pri nekaterih otrocih so ugotovili, da imajo izredno hitro presnovo s CYP2D6.
English: • Codeine is now only indicated in patients older than 12 years of age for the treatment of acute moderate pain that cannot be relieved by other analgesics such as paracetamol or ibuprofen (alone).
Slovenian: • Kodein je po novem indiciran samo pri bolnikih, starejših od 12 let, za zdravljenje akutne zmerne bolečine, ki je ni mogoče ublažiti z drugimi analgetiki, na primer s paracetamolom ali ibuprofenom (kot monoterapijo).
English: The children who had suffered severe side effects had evidence of being ‘CYP2D6 ultra-rapid metabolisers' of codeine.
Slovenian: Otroci, pri katerih so se pojavili hudi neželeni učinki, so imeli znake „izredno hitre presnove kodeina s CYP2D6.
English: • All children (aged below 18 years) who undergo surgery for the removal of the tonsils or adenoids to treat obstructive sleep apnoea (frequent interruption of breathing during sleep) should not be given codeine as they are more at risk of breathing problems.
Slovenian: • Kodein se ne sme dajati otrokom (mlajšim od 18 let), ki so prestali operacijo za odstranitev tonzil ali žrelnic zaradi obstruktivne apneje med spanjem (pogostih prekinitev dihanja med spanjem), saj pri njih obstaja povečano tveganje za težave z dihanjem.
English: The reason for this longer half-life is unknown.
Slovenian: Razlog za daljši razpolovni čas ni poznan.
English: Dogs aged 12 months or more.
Slovenian: Psi, stari 12 mesecev ali več.
English: Bodyweight (kg)
Slovenian: Telesna teža (kg)
English: In rare cases these adverse reactions may be fatal.
Slovenian: V redkih primerih so ti neželeni učinki lahko smrtni.
English: ATCvet code: QM01AH92.
Slovenian: Oznaka ATC vet: QM01AH92
English: Particular attention should be paid to maintaining haemodynamic status.
Slovenian: Posebna pozornost naj se nameni ohranjanju hemodinamičnega statusa.
English: Do not use in dogs less than 12 months of age and/or less than 5 kg body weight.
Slovenian: Ne uporabite pri psih, mlajših od 12 mesecev in/ali lažjih od 5 kg telesne teže.
English: Località Marino del Tronto 63100 Ascoli Piceno (AP) ITALY
Slovenian: Località Marino del Tronto 63100 Ascoli Piceno (AP) ITALIJA
English: MARKETING AUTHORISATION NUMBER(S) EU/2/08/084/001-005
Slovenian: ŠTEVILKA(E) DOVOLJENJ(A) ZA PROMET EU/2/08/084/001-005
English: Steady state pharmacokinetics was attained by the fourth treatment in most animals.
Slovenian: Enakomerno farmakokinetično stanje zdravila je bilo pri večini živali doseženo s četrtim zdravljenjem.
English: Do not exceed the stated dose prescribed by your veterinarian.
Slovenian: Ne prekoračite odmerka, ki ga je predpisal vaš veterinar.
English: Mavacoxib is 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide.
Slovenian: Mavakoksib je 4-[5-(4-florofenil)-3-(triflorometil)-1H-pirazol-1-yl]-benzensulfonamid.
English: Pre-treatment with other anti-inflammatory substances may result in additional or increased adverse effects.
Slovenian: Predhodno zdravljenje z drugimi nesteroidnimi protivnetnimi zdravili lahko povzroči dodatne ali povečane neželene učinke.
English: Date of last renewal: 12/08/2013.
Slovenian: Datum podaljšanja dovoljenja za promet: 12/08/2013.
English: A maximum treatment administration of 6.5 months continuous therapy is recommended so as to manage plasma levels of mavacoxib in animals which exhibit reduced elimination
Slovenian: Priporočena je maksimalna neprekinjena terapija 6,5 mesecev za obvladovanje koncentracije mavakoksiba v plazmi pri živalih, ki kažejo znake zmanjšane eliminacije.
English: Mavacoxib is well absorbed after oral administration; bioavailability was 87% in fed dogs and 46 % in fasted conditions and the recommended dose is based on administration with food.
Slovenian: Mavakoksib se dobro absorbira po peroralnem dajanju; biološka razpoložljivost je bila 87 % pri hranjenih psih in 46 % v postnem stanju, priporočen odmerek pa je določen glede na dajanje skupaj s hrano.
English: The dose of Trocoxil chewable tablets is 2 mg/kg of body weight (see table below).
Slovenian: Odmerek Trocoxil žvečljivih tablet je 2 mg/kg telesne teže (glejte spodaj navedeno tabelo).
English: Based on the results of canine whole blood assays, plasma concentrations producing 20% COX-1 inhibition and 80% COX-2 inhibition were 2.46 µg/mL and 1.28 µg/mL, respectively, so that the IC20COX-1:IC80COX-2 potency ratio is approximately 2:1, whilst the IC80COX-1:IC80COX-2 potency ratio is approximately 40:1.
Slovenian: Na podlagi rezultatov celotne analize pasje krvi, so bile koncentracije v plazmi, ki so proizvedle 20 % COX-1 inhibicijo in 80 % COX-2 inhibicijo 2,46 µg/ml in 1,28 µg/ml, tako da je razmerje učinkovitosti IC20COX-1:IC80COX-2 približno 2:1, medtem ko je IC80COX-1:IC80COX-2 razmerje učinkovitosti približno 40:1.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 09/09/2008
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum pridobitve dovoljenja za promet: 09/09/2008.
English: In laboratory studies with young adult dogs, mean elimination half-life values ranged from 13.8 to 19.3 days.
Slovenian: V laboratorijskih študijah pri mlajših odraslih psih je bil srednji razpolovni časa eliminacije od 13,8 do 19,3 dni.
English: Therapeutic concentrations in fed dogs are reached rapidly and peak concentrations are obtained in less than 24 hours after administering a dose.
Slovenian: Terapevtska koncentracija je pri hranjenih psih hitro dosežena, najvišja koncentracija je dosežena v manj kot 24 urah po dajanju odmerka.
English: Adverse reactions could occur at any timepoint during this period.
Slovenian: Neželeni učinki se lahko pojavijo v katerem koli trenutku v tem časovnem obdobju.
English: The key aim of intervention is to maintain renal perfusion.
Slovenian: Ključni cilj ukrepanja je ohranitev funkcije ledvic.
English: There are two isoforms of COX, COX-1, and COX-2.
Slovenian: Obstajata dve izomeri ciklooksigenaze, COX-1 in COX-2.
English: Do not use in cases of heart insufficiency.
Slovenian: Ne uporabite v primeru insuficience srca.
English: Population pharmacokinetic data derived from studies in dogs with a predominantly older population with heavier dogs as compared to the experimental studies (mean 9 years of age) showed that the mean elimination half-life was 39 days with a small sub-population (<5%) having an elimination half-life of more than 80 days and correspondingly an increased exposure was recorded in these individuals.
Slovenian: Farmakokinetični podatki populacije iz študij, v kateri so prevladovali starejši in težji psi v primerjavi z eksperimentalno študijo (povprečna starost 9 let), so pokazali, da je povprečen eliminacijski razpolovni čas 39 dni z manjšo subpopulacijo (<5 %), ki je imela eliminacijski razpolovni čas več kot 80 dni .Ustrezno je bila zabeležena tudi povečana izpostavljenost pri teh posameznikih.
English: Veterinarians should be aware that clinical signs of adverse reactions may continue when supportive therapy (such as gastro protectants) is discontinued.
Slovenian: Veterinarji se naj zavedajo, da se lahko klinični znaki nadaljujejo, ko se podporna terapija (kot so zdravila za zaščito želodca) prekine.
English: A treatment cycle should not exceed 7 consecutive doses (6.5 months).
Slovenian: Ciklus zdravljenja naj ne preseže 7 zaporednih odmerkov (6,5 mesecev).
English: No drug interaction studies have been performed.
Slovenian: Študije o medsebojnem delovanju z drugimi zdravili niso bile izvedene.
English: The principal mode of action is inhibition of cyclooxygenase (COX).
Slovenian: Osnovni način delovanja je inhibicija ciklooksigenaze (COX).
English: PACKAGE SIZE 2 tablets
Slovenian: VELIKOST PAKIRANJA 2 tableti
English: Manufacturer responsible for batch release: Pfizer Italia s.r.l.
Slovenian: Proizvajalec odgovoren za sproščanje serij:Pfizer Italia s.r.l.
English: Risks for interactions have to be accounted for throughout the effect period i.e. 1-2 months after administration of Trocoxil.
Slovenian: Tveganje za medsebojno delovanje zdravil je potrebno upoštevati v celotnem obdobju delovanja, kar je 1-2 meseca po dajanju Trocoxila.
English: It is a diarylsubstituted pyrazole.
Slovenian: Je pirazol, substituiran z diarilom .
English: Tablets also contain the following ingredients
Slovenian: Tableta vsebuje tudi naslednje snovi:
English: Wash hands after handling the product.
Slovenian: Po dajanju zdravila si umijte roke.
English: The dose is 2 mg mavacoxib per kg body weight given immediately before or with the dog's main meal.
Slovenian: Odmerek je 2 mg mavakoksiba na kg telesne teže, ki se da psu tik pred ali z glavnih obrokom hrane.
English: 95 mg For the full list of excipients, see section 6.1.
Slovenian: Za celoten seznam pomožnih snovi, glejte poglavje 6.1.
English: Similarly adverse reactions occurring at the use dose in the animal population principally involved the gastrointestinal system.
Slovenian: Podobno so neželeni učinki, ki so se pojavili v populaciji živali pri uporabi predpisanega odmerka, vključevali predvsem gastro-intestinalni sistem.
English: Its activity culminates in the synthesis of local hormones and inflammatory mediators, termed eicosanoids, which include several prostaglandins.
Slovenian: Njegova aktivnost je največja pri sintezi lokalnih hormonov in vnetnih mediatorjev, imenovanih eikozanoidi, ki vključujejo številne prostaglandine.
English: Use the dose prescribed by the veterinarian.
Slovenian: Uporabite odmerek, ki ga predpiše veterinar.
English: THIS IS NOT A DAILY TREATMENT.
Slovenian: NAVEDENA TERAPIJA NI ZA DNEVNO UPORABO.
English: If your dog needs surgery, inform the surgeon that the dog is using Trocoxil.
Slovenian: Če vaš pes potrebuje kirurški poseg, opozorite lečečega veterinarja, da žival prejema Trocoxil.
English: The treatment-free period should however, take into account the pharmacology of the medicinal products used previously.
Slovenian: Pri časovnem presledku je potrebno upoštevati farmakokinetiko predhodno uporabljenega zdravila.
English: ADVICE ON CORRECT ADMINISTRATION Trocoxil should be given immediately before or during the animal's main meal.
Slovenian: NASVET O PRAVILNI UPORABI ZDRAVILA Trocoxil se daje živali tik pred ali med glavnim obrokom hrane.
English: The safety of Trocoxil has not been established during pregnancy and lactation.
Slovenian: Varnost Trocoxila ni bila ugotovljena med brejostjo in laktacijo.
English: Shelf life of the veterinary medicinal product as packaged for sale: 3 years
Slovenian: Rok uporabnosti zdravila v pakiranju za prodajo: 3 leti.
English: Both COX-1 and COX-2 are present constitutively in the kidney and are assumed to possess protective roles in adverse physiological circumstances.
Slovenian: Oba, COX-1 in COX-2, sta v osnovi prisotna v ledvicah in imata predvidoma zaščitno vlogo v neželenih fizioloških okoliščinah.
English: The products of COX-2 metabolism are also involved in ovulation, implantation and closure of the ductus arteriosus.
Slovenian: Produkti metabolizma COX-2 so vpleteni tudi pri ovulaciji, ugnezdenju zarodka in zaprtju arterioznega duktusa.
English: STATEMENT OF THE ACTIVE SUBSTANCE(S) AND OTHER INGREDIENT(S) Active substance:
Slovenian: NAVEDBA UČINKOVIN(E) IN DRUGE(IH) SESTAVIN Zdravilna učinkovina:
English: Carton boxes containing one blister.
Slovenian: Kartonska škatla vsebuje 1 pretisni omot.
English: A treatment cycle with Trocoxil should not exceed 7 consecutive doses (6.5 months).
Slovenian: Cikel zdravljenja s Trocoxilom naj ne preseže 7 zaporednih odmerkov (6,5 mesecev).
English: COX is a key enzyme in pathways of arachidonic acid metabolism.
Slovenian: COX je ključni encim v kaskadi metabolizma arahidonske kisline.
English: Trocoxil should not be used in dehydrated dogs.
Slovenian: Trocoxila se ne daje dehidriranim psom.
English: Animals with evidence of impaired renal or hepatic function, or with evidence of a protein or blood losing enteropathy are not suitable for treatment with Trocoxil.
Slovenian: Živali z znaki oslabelega delovanja ledvic ali jeter ali z znaki izgubljanja proteinov ali enteropatično izgubo krvi, niso primerne za zdravljenje s Trocoxilom.
English: For this reason dogs with hepatic disorders should not be treated.
Slovenian: Zaradi teh razlogov naj se psov z motnjami v delovanju jeter ne zdravi.
English: Care should be taken to avoid treatment of animals that might not tolerate prolonged NSAID exposure.
Slovenian: Potrebna je previdnost pri zdravljenju živali, ki ne tolerirajo dolgotrajnega izpostavljanja nesteroidnim protivnetnim zdravilom.
English: Adverse reactions could occur at any time point during this period.
Slovenian: Neželeni učinki se lahko pojavijo kadarkoli v tem času.
English: However, studies in laboratory animals administered other NSAIDs have shown increased pre- and post-implantation loss, embryo-foetal lethality, and malformations.
Slovenian: Študije na laboratorijskih živali, ki so prejele druga nesteroidna protivnetna zdravila, so pokazale povečane izgube pred in po ugnezdenju zarodka, povečano embrionalno-fetalno smrtnost in malformacije.
English: Do not eat, drink, or smoke when handling the product.
Slovenian: Med rokovanjem z zdravilom ne jejte, pijte ali kadite.
English: MANUFACTURER'S BATCH NUMBER Lot
Slovenian: PROIZVAJALČEVA ŠTEVILKA SERIJE Lot {številka}
English: For the treatment of pain and inflammation associated with degenerative joint disease in dogs in cases where continuous treatment exceeding one month is indicated.
Slovenian: Zdravljenje bolečine in vnetja, povezanega z degenerativnim obolenjem sklepov pri psih, v primerih kjer je indicirano zdravljenje, daljše od enega meseca.
English: Tell your veterinarian if your dog is using a blood-thinning agent.
Slovenian: Povejte vašemu veterinarju, če vaš pes prejema zdravila za redčenje krvi.
English: COX-1 is a widely distributed constitutive enzyme, primarily involved in maintaining organ and tissue function, whilst COX-2 is inducible at sites of tissue damage but in some organs it is also constitutive.
Slovenian: COX-1 je široko razporejen osnovni encim, ki je primarno vpleten v ohranjaje funkcij organov in tkiv, medtem ko je COX-2 encim, ki se pojavi na mestu poškodbe tkiva, vendar je v nekaterih organih prisoten tudi kot osnovni encim.
English: It is recommended to repeat the clinical examination one month after commencing treatment with Trocoxil and prior to administration of the third dose with additional monitoring of clinical pathology as appropriate during treatment.
Slovenian: Klinični pregled je priporočljivo ponoviti en mesec po začetku zdravljenja s Trocoxilom in pred dajanjem tretjega odmerka, dodatno spremljanje klinične patologije pa po potrebi med zdravljenjem.
English: In overdose safety studies, repeated doses of 5 mg/kg and 10 mg/kg were not associated with adverse clinical events, abnormal clinical chemistry or significant histological abnormalities.
Slovenian: V študiji varnosti zdravila pri prevelikem odmerjanju, ponavljajoči odmerki 5 mg/kg in 10 mg/kg niso pokazali neželenih kliničnih učinkov, nenormalne klinične kemične slike ali očitnih histoloških sprememb.
English: Do not use concomitantly with glucocorticoids or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), see section 4.8.
Slovenian: Ne uporabite istočasno z glukokortikoidi ali drugimi nesteroidnimi protivnetnimi zdravili (NSAID) (glejte poglavje 4.8).
English: Trocoxil belongs to a group of medicines called Non-steroidal Anti-inflammatory drugs (NSAIDs) which are used to treat pain and inflammation.
Slovenian: Trocoxil spada v skupino zdravil imenovanih nesteroidna protivnetna zdravila (NSAID), ki se uporabljajo za zdravljenje bolečine in vnetja.
English: Before prescribing Trocoxil and during treatment with Trocoxil, your veterinarian will check your dog for kidney and liver problems as well as for diseases of the intestines.
Slovenian: Pred predpisano uporabo Trocoxila in med samim zdravljenjem bo vaš veterinar pregledal psa ali ima probleme z delovanjem ledvic in jeter kot tudi za prisotnost bolezni prebavil.
English: If an adverse reaction to the administration of Trocoxil occurs, stop using the product, and seek medical advice from your veterinarian immediately.
Slovenian: Če se pojavi neželen učinek po dajanju Trocoxila, zdravilo prenehajte uporabljati in takoj poiščite nasvet pri vašem veterinarju.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Veterinary medicinal product subject to prescription.
Slovenian: B. POGOJI TER OMEJITVE GLEDE OSKRBE IN UPORABE Na veterinarski recept.
English: Do not use this veterinary medicinal product after the expiry date which is stated on the carton and blister after Exp.
Slovenian: Zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na zunanji ovojnini in pretisnem omotu po EXP.
English: -Blister foil base: PVC film /aluminium foil/ nylon -Blister backing: vinyl heat seal coating /aluminium foil/polyester film/printable paper Not all pack sizes may be marketed.
Slovenian: -osnova folije pretisnega omota: PVC film / aluminijasta folija / najlon -hrbtna stran pretisnega omota: toplotno zavarjena vinilna prevleka /aluminijasta folija / poliesterski film / papir za tiskanje
English: Trocoxil has an extended effect duration (up to 2 months after administration of the second dose and following doses).
Slovenian: Trocoxil ima podaljšano delovanje (do 2 meseca po dajanju drugega odmerka in sledečih odmerkih).
English: NSAIDs are highly bound to plasma proteins and may compete with other highly bound substances, such that concomitant administration may result in toxic effects.
Slovenian: NSAID se v visokem odstotku vežejo na plazemske beljakovine in lahko tekmujejo z drugimi snovmi z visoko vezavo na plazemske beljakovine, kar se lahko odrazi s toksičnim učinkom.
English: Do not use in case of known hypersensitivity to sulphonamides.
Slovenian: Ne uporabite v primeru znane preobčutljivosti na sulfonamide.
English: PHARMACEUTICAL FORM Chewable tablets
Slovenian: FARMACEVTSKA OBLIKA Žvečljive tablete
English: Ensure appropriate hydration and haemodynamic status when animals receiving Trocoxil undergo anaesthesia and/or surgical procedures or develop conditions which may result in dehydration or compromised haemodynamic status.
Slovenian: Zagotovite primerno hidracijo in hemodinamični status živali, ki prejemajo mavakoksib in so v anesteziji in/ali kirurškem posegu ali v primeru pojava bolezni, ki lahko imajo za posledico dehidracijo ali prizadet hemodinamični status.
English: Care should be taken to ensure that the tablet is ingested.
Slovenian: Zagotovite, da je bila tableta zaužita.
English: Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of increased renal toxicity.
Slovenian: Izogibajte se uporabi pri dehidrirani, hipovolemični in hipotenzični živali, ker obstaja možnost povečane renalne toksičnosti.
English: Triangular tablet with mottled brown appearance embossed with the tablet strength on one side, the reverse side is blank.
Slovenian: Trikotna tableta lisasto rjavega videza, na eni strani izbočena in označena z jakostjo tablet, na drugi strani je prazna.
English: People with known hypersensitivity to NSAIDs should avoid contact with the veterinary medicinal product.
Slovenian: Osebe z znano preobčutljivostjo na nesteroidna protivnetna zdravila naj se izogibajo stiku z zdravilom.
English: COX-2 exerts the major role in synthesising prostaglandins which have pivotal roles as mediators of pain, inflammation and fever.
Slovenian: COX-2 ima odločilno vlogo pri sintezi prostaglandinov, ki imajo ključno vlogo kot mediatorji bolečine, vnetja in povišane telesne temperature.
English: Pharmacotherapeutic group: Anti-inflammatory and anti-rheumatic products, non-steroids, Coxibs.
Slovenian: Farmakoterapevtska skupina: nesteroidna protivnetna in protirevmatična zdravila, koksibi.
English: The initial treatment should be repeated 14 days later, thereafter the dosing interval is one month.
Slovenian: Začetno zdravljenje naj se ponovi čez 14 dni, nato je interval med odmerki en mesec.
English: Mavacoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class.
Slovenian: Mavakoksib je nesteroidno protivnetno zdravilo (NSAID) iz razreda koksibov.
English: In the overdose studies, in common with other NSAIDs, adverse pharmacodynamic events occur affecting the gastrointestinal system.
Slovenian: V študijah s prevelikim odmerjanjem so se kot pri drugih nesteroidnih protivnetnih zdravilih, pojavili neželeni farmakodinamični primeri, ki so vplivali na gastro-intestinalni sistem.
English: Should another NSAID be administered after Trocoxil treatment, a treatment-free period of at least ONE MONTH should be ensured to avoid adverse effects.
Slovenian: Če se bo za Trocoxilom apliciralo drugo nesteroidno protivnetno zdravilo, je potrebno zagotoviti obdobje brez zdravljenja vsaj EN MESEC, da se izognete neželenim učinkom.
English: At 15 mg/kg there was evidence of vomiting, and softened/mucoid faeces and an increase in clinical chemistry parameters reflecting renal function.
Slovenian: Pri odmerku 15 mg/kg so se pojavili znaki bruhanja, mehkejše/sluzasto blato in povišanje kemičnih parametrov, ki kažejo na delovanje ledvic.
English: C. STATEMENT OF THE MRLs Not applicable.
Slovenian: C. NAVEDBA NAJVIŠJIH DOVOLJENIH KOLIČIN OSTANKOV ZDRAVILA (MRL) Ni smiselno
English: Trocoxil chewable tablets are indicated for the treatment of pain and inflammation associated with degenerative joint disease in dogs where treatment for more than one month is needed.
Slovenian: Trocoxil žvečljive tablete so indicirane za zdravljenje bolečine in vnetja, ki je povezano z degenerativnim obolenjem sklepov pri psih, kjer je indicirano zdravljenje, daljše od enega meseca.
English: Do not use in dogs suffering from gastro-intestinal disorders including ulceration and bleeding.
Slovenian: Ne uporabite pri psih z motnjami v delovanju gastro-intestinalnega sistema vključno z ulkusi in krvavitvami.
English: At 25 mg/kg there was evidence of gastrointestinal ulceration.
Slovenian: Pri odmerku 25 mg/kg so se pojavili znaki gastro intestinalnih ulkusov.
English: Gastrointestinal ulceration was reported in rare cases.
Slovenian: Poročali so o redkih primerih gastrointestinalnih ulceracij.
English: Silicified microcrystalline cellulose Artificial powdered beef flavour Croscarmellose sodium Sodium laurylsulfate Magnesium stearate
Slovenian: Celuloza, silikatna, mikrokristalna Umetna aroma govedine, prah Natrijev karmelozat, premreženi Natrijev lavrilsulfat Magnezijev stearat
English: The treatment should be repeated 14 days later, thereafter the dosing interval is ONE MONTH.
Slovenian: Zdravljenje se ponovi čez 14 dni, nato pa je obdobje med odmerjanjem EN MESEC.