FrancophonIA/ELRC3.0 huggingface dataset:
English: Artemether/lumefantrine/efaviren z (20/120 mg tablet, 6 doses of 4 tablets each over 3 days/600mg once daily)
Danish: Artemether/lumefantrin/efavirenz (20/120 mg tablet, 6 doser af 4 tabletter hver over 3 dage/600 mg en gang dagligt)
English: If efavirenz is co-administered with voriconazole, the voriconazole maintenance dose must be increased to 400 mg every 12 hours and the efavirenz dose must be reduced by 50%, i.e. to 300 mg once daily.
Danish: Hvis efavirenz administreres sammen med voriconazol, skal vedligeholdelsesdosis af voriconazol øges til 400 mg hver 12. time, og dosis af efavirenz skal reduceres med 50%, dvs. til 300 mg en gang dagligt.
English: Other macrolide antibiotics (e.g. erythromycin)/efavirenz
Danish: Andre makrolidantibiotika (f.eks. erythromycin)/efavirenz
English: - If you have severe liver disease.
Danish: Hvis du har alvorlig leversygdom, må du ikke tage
English: Cmax: ↑ 11% (↑ 6 to ↑ 16)
Danish: Cmax: ↑ 11% (↑ 6 til ↑ 16)
English: Talk to your doctor before taking Efavirenz Teva
Danish: Kontakt lægen, før du tager Efavirenz Teva.
English: Efavirenz Teva 600 mg film-coated tablets Efavirenz
Danish: Efavirenz Teva 600 mg filmovertrukne tabletter Efavirenz
English: Cmin: ↓ 12% (↓ 24% to ↑ 1%)
Danish: Cmin: ↓ 12% (↓ 24 til ↑ 1)
English: Study number/ Treatment regimensb n % (95% C.I.c) % (95% C.I.c) cells/mm3
Danish: % (95% C.I.c) % (95% C.I.c) celler/mm3 (S.E.M.d)
English: Each film-coated tablet contains 9.98 mg lactose (as monohydrate).
Danish: Hjælpestof, som behandleren skal være opmærksom på Hver filmovertrukken tablet indeholder 9,98 mg lactose (i form af monohydrat).
English: Efavirenz must not be administered concurrently with terfenadine, astemizole, cisapride, midazolam, triazolam, pimozide, bepridil, or ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine), since inhibition of their metabolism may lead to serious, life-threatening events (see section 4.3).
Danish: Efavirenz må ikke administreres sammen med terfenadin, astemizol, cisaprid, midazolam, triazolam, pimozid, bepridil eller ergotalkaloider (f.eks. ergotamin, dihydroergotamin, ergonovin og methylergonovin), da hæmning af disses metabolisme kan føre til alvorlige livstruende hændelser (se pkt.
English: In a study of HIV infected intravenous drug users, co-administration of efavirenz with methadone resulted in decreased plasma levels of methadone and signs of opiate withdrawal.
Danish: I en undersøgelse med hivinficerede brugere af intravenøse stoffer resulterede samtidig administration af efavirenz og methadon i nedsat plasmakoncentration af methadon og abstinenssymptomer.
English: Depomedroxyprogesterone acetate (DMPA)/efavirenz (150 mg IM single dose DMPA)
Danish: Depomedroxyprogesteronacet at (DMPA)/efavirenz (150 mg enkeltdosis DMPA intramuskulært)
English: Co-administration of efavirenz with the fixed-combination tablet containing efavirenz, emtricitabine, and tenofovir disoproxil is not recommended, unless needed for dose adjustment (for example, with rifampicin).
Danish: Efavirenz og den faste kombinationstablet indeholdende efavirenz, emtricitabin og tenofovirdisoproxil, bør ikke administreres samtidigt samtidigt medmindre det er nødvendigt for dosisjustering (fx ved samtidig behandling med rifampicin).
English: When efavirenz is co-administered with an anticonvulsant that is a substrate of CYP450 isoenzymes, periodic monitoring of anticonvulsant levels should be conducted.
Danish: antikonvulsivum, som er et substrat for CYP450isoenzymer, bør regelmæssig monitorering af antikonvulsivakoncentrationen foretages.
English: Carcinogenicity studies in male mice, male and female rats were negative.
Danish: Carcinogenecitetsundersøgelser på hanmus samt han- og hunrotter var negative.
English: AUC: ↔*/** (↓ 10 to ↑ 26) Cmax: ↔*/** (↓ 5 to ↑ 26) Cmin: ↑ 12%*/** (↓ 16 to ↑ 49)
Danish: AUC: ↔*/** (↓ 10 til ↑ 26) Cmax: ↔*/** (↓ 5 til ↑ 26) Cmin: ↑ 12%*/** (↓ 16 til ↑ 49)
English: (400/100 mg twice daily/ 600 mg once daily)
Danish: (400/100 mg to gange dagligt/600 mg én gang dagligt)
English: Lopinavir concentrations: similar to lopinavir/ritonavir 400/100 mg twice daily without efavirenz
Danish: Lopinavirkoncentrationer: Samme som for lopinavir/ritonavir 400/100 mg to gange dagligt uden efavirenz.
English: Breast-feeding should be discontinued during treatment with efavirenz.
Danish: Amning skal ophøre under behandling med efavirenz.
English: Efavirenz may cause dizziness, impaired concentration, and/or somnolence.
Danish: Efavirenz kan forårsage svimmelhed, nedsat koncentrationsevne og/eller døsighed.
English: (CYP3A4 and CYP2B6 induction)
Danish: (CYP3A4- og CYP2B6induktion)
English: - nervousness, forgetfulness, confusion, fitting (seizures), abnormal thoughts - blurred vision - a feeling of spinning or tilting (vertigo) - pain in the abdomen (stomach) caused by inflammation of the pancreas - allergic reaction (hypersensitivity) that may cause severe skin reactions (erythema multiforme,
Danish: - Nervøsitet, glemsomhed, forvirring, anfald (kramper), unormale tanker - Sløret syn - Snurrende eller gyngende fornemmelse (svimmelhed) - Smerter i maven forårsaget af betændelse i bugspytkirtlen - Allergisk reaktion (overfølsomhed) som kan medføre alvorlige hudreaktioner (erythema multiforme, Stevens-Johnsons syndrom) - Gulfarvning af hud eller øjne, kløe, eller smerter i maven forårsaget af betændelse i leveren - Brystforstørrelse hos mænd - Aggressiv opførsel, humørsvingninger, at se eller høre ting, som i virkeligheden ikke er der
English: Sufficient data on the tolerability of efavirenz with low-dose ritonavir (100 mg, once or twice daily) are not available.
Danish: Anbefaling vedrørende samtidig administration med efavirenz efavirenz sammen med ritonavir 100 mg i lav dosis (én eller to gange dagligt) er ikke tilgængelige.
English: Efavirenz in combination with darunavir/ritonavir 800/100 mg once daily may result in suboptimal darunavir Cmin.
Danish: 800/100 mg én gang dagligt kan resultere i suboptimal darunavir Cmin.
English: IDV + NRTIs a NC = F, noncompleter = failure.
Danish: IDV + NRTI'ere 170 51 (43, 59) a NC = F, non-completer = failure.
English: Uncommon (affects 1 to 10 users in 1,000)
Danish: Ikke almindelige (berører 1 til 10 ud af 1.000 brugere)
English: Recommendation concerning co-administration with efavirenz gabapentin are exclusively eliminated unchanged in the urine and are unlikely to compete for the same metabolic enzymes and elimination pathways as efavirenz.
Danish: Der forventes ingen klinisk signifikante interaktioner, da vigabatrin og gabapentin udelukkende elimineres uændret i urinen, og derfor konkurrerer de sandsynligvis ikke om de samme metaboliske enzymer og eliminationsveje som efavirenz.
English: EFV + NFV + NRTIs
Danish: EFV + NFV +
English: No clinically significant pharmacokinetic interaction
Danish: Ingen klinisk signifikant farmakokinetisk interaktion
English: - certain antibiotics including some agents of the following classes: macrolides, fluoroquinolones,
Danish: - Antibiotika, herunder følgende typer: makrolider, fluoroquinoloner eller imidazol.
English: Efavirenz Teva 600 mg film-coated tablets
Danish: Efavirenz Teva 600 mg filmovertrukne tabletter
English: AUC: ↑ 21% Cmin: ↑ 17% Cmax: ↑ 15%
Danish: AUC: ↑ 21% Cmin: ↑ 17%
English: if you have a history of convulsions (fits or seizures) or if you are being treated with anticonvulsant therapy such as carbamazepine, phenobarbital and phenytoin.
Danish: hvis du tidligere har haft krampeanfald, eller hvis du får medicin mod krampeanfald, for eksempel carbamazepin, phenobarbital og phenytoin.
English: ANTICOAGULANTS Warfarin/efavirenz Acenocoumarol/efavirenz
Danish: Warfarin/efavirenz Acenocoumarol/efavirenz
English: Ethinyloestradiol + norgestimate / efavirenz (0.035 mg + 0.25 mg once daily/600 mg once daily)
Danish: Ethinylestradiol + norgestimat/efavirenz (0,035 mg + 0,25 mg én gang dagligt/600 mg én gang dagligt)
English: Efavirenz Teva contains efavirenz and may cause dizziness, impaired concentration, and drowsiness.
Danish: Trafik- og arbejdssikkerhed Efavirenz Teva indeholder efavirenz og kan give svimmelhed, nedsat koncentrationsevne og døsighed.
English: - Medicines used to treat convulsions/seizures (anticonvulsants): carbamazepine, phenytoin,
Danish: - Medicin til behandling af krampeanfald: carbamazepin, phenytoin, phenobarbital.
English: AUC: ↔* (↓ 9 to ↑ 10) Cmax: ↑ 17%* (↑ 8 to ↑ 27) Cmin: ↓ 42%* (↓ 31 to ↓ 51)
Danish: AUC: ↔* (↓ 9 til ↑ 10) Cmax: ↑ 17%* (↑ 8 til ↑ 27) Cmin: ↓ 42%* (↓ 31 til ↓ 51)
English: Efavirenz can be re-initiated in patients interrupting therapy because of rash.
Danish: Efavirenzbehandling kan genoptages hos patienter, der afbryder behandlingen på grund af udslæt.
English: Forty-three patients 3 months to 21 years of age (median 9.6 years) were dosed with efavirenz.
Danish: 43 patienter, mellem 3 måneder og 21 år (gennemsnit 9,6 år) blev behandlet med SUSTIVA.
English: Concomitant administration of velpatasvir/sofosbuvir/ voxilaprevir with efavirenz is not recommended, as it may decrease concentrations of velpatasvir and voxilaprevir.
Danish: Samtidig administration af velpatasvir/sofosbuvir/voxilapr evir med efavirenz anbefales ikke, da det kan medføre fald i koncentrationerne af
English: In 35 patients receiving efavirenz 600 mg once daily, steady-state Cmax was 12.9 ± 3.7 microM (29%) [mean ± S.D. (% C.V.)], steady-state Cmin was 5.6 ± 3.2 microM (57%), and AUC was 184 ± 73 microM·h (40%).
Danish: Hos 35 patienter, der fik efavirenz 600 mg 1 gang daglig var det gennemsnitlige steady-state Cmax 12,9 ± 3,7 mikroM (29%) [gennemsnit ± S.D. (% C.V.
English: Methadone/efavirenz (stable maintenance, 35-100 mg once daily/600 mg once daily)
Danish: Methadon/efavirenz (stabil vedligeholdelse, 35-100 mg én gang dagligt/600 mg én gang dagligt)
English: Your doctor will check your cholesterol levels and will consider changing the dose of your statin, if needed.
Danish: Lægen vil kontrollere dit kolesterol i blodet og måske ændre din statindosis.
English: (CYP3A4 induction) * When compared to atazanavir 300 mg/ritonavir 100 mg once daily in the evening without efavirenz.
Danish: * Ved sammenligning med atazanavir 300 mg/ritonavir 100 mg én gang dagligt om aftenen uden efavirenz.
English: AUC: ↔ Cmax: ↑ 11% (↑ 3 to ↑19)
Danish: AUC: ↔ Cmax: ↑ 11% (↑ 3 til ↑19)
English: Study AI266922 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with didanosine and emtricitabine in antiretroviral-naive and -experienced paediatric patients.
Danish: Studie AI266922 var et ikke-blindet studie til evaluering af efavirenz' farmakokinetik, sikkerhed, tolerabilitet og antivirale aktivitet i kombination med didanosin og emtricitabin hos antiretroviralnaive og -erfarne pædiatriske patienter.
English: If you forget to take Efavirenz Teva
Danish: Hvis du har glemt at tage Efavirenz Teva
English: NRTIs and NNRTIs NRTIs/efavirenz
Danish: NRTIer og NNRTIer NRTIer/efavirenz
English: Study PACTG 382 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with nelfinavir and an NRTI in antiretroviral-naive and NRTI-experienced paediatric patients.
Danish: Studie PACTG 382 var et ikke-blindet studie til evaluering af efavirenz' farmakokinetik, sikkerhed, tolerabilitet og antivirale aktivitet i kombination med en nelfinavir og en NRTI hos antiretroviral-naive og NRTI-erfarne pædiatriske patienter.
English: Interactions between efavirenz and protease inhibitors, antiretroviral agents other than protease inhibitors and other non-antiretroviral medicinal products are listed in Table 1 below (increase is indicated as “↑”, decrease as “↓”, no change as “↔”, and once every 8 or 12 hours as “q8h” or “q12h”).
Danish: "↑", fald som "↓", ingen ændring som "↔" og én gang hver 8. eller 12. time som "q8h" eller "q12h").
English: AUC: ↓ 31% (↓ 8 to ↓47) Cmin: ↓ 40%
Danish: AUC: ↓ 31% (↓ 8 til ↓47) Cmin: ↓ 40%
English: There is a potential for reduction or increase in the plasma concentrations of phenytoin, phenobarbital and other anticonvulsants that are substrates of CYP450 isoenzymes when co-administered with efavirenz.
Danish: Anbefaling vedrørende samtidig administration med efavirenz phenytoin, phenobarbital og andre antikonvulsiva, som er substrater for CYP450-isoenzymer, kan eventuelt falde eller stige, når disse administreres samtidigt med efavirenz.
English: Concomitant administration of glecaprevir/pibrentasvir with efavirenz may significantly decrease plasma concentrations of glecaprevir and pibrentasvir, leading to reduced therapeutic effect.
Danish: Samtidig administration af glecaprevir/pibrentasvir med efavirenz kan medføre signikant fald i plasmakoncentrationerne af glecaprevir og pibrentasvir og medføre nedsat terapeutisk effekt.
English: The clinical outcome of this observed reduction of boceprevir trough concentrations has not been directly assessed.
Danish: boceprevir koncentrationerne er ikke direkte vurderet.
English: AUC: ↓ 52% (↓ 33 to ↓ 66) Cmax: ↓ 45% (↓ 25 to ↓ 59) (CYP3A4 induction)
Danish: AUC: ↓ 52% (↓ 33 til ↓ 66) Cmax: ↓ 45% (↓ 25 til ↓ 59) (CYP3A4-induktion)
English: AUC: ↓ 36% (↓ 32 to ↓ 40) Cmax: ↓ 21% (↓ 15 to ↓ 26) Cmin: ↓ 47% (↓ 41 to ↓ 53) (decrease in carbamazepine concentrations: CYP3A4 induction; decrease in efavirenz concentrations: CYP3A4 and CYP2B6 induction)
Danish: AUC: ↓ 36% (↓ 32 til ↓ 40) Cmax: ↓ 21% (↓ 15 til ↓ 26) Cmin: ↓ 47% (↓ 41 til ↓ 53) (fald i carbamazepinkoncentrationen: CYP3A4-induktion; fald i efvirenzkoncentrationen: CYP3A4- og
English: Efavirenz Teva may reduce the amount of posaconazole in your blood.
Danish: Efavirenz Teva kan mindske mængden af posaconazol i blodet.
English: Efavirenz Teva can reduce the amount of statins in your blood.
Danish: Efavirenz Teva kan nedsætte mængden af statiner i blodet.
English: Efavirenz Teva may reduce the amount of itraconazole in your blood.
Danish: Efavirenz Teva kan mindske mængden af itraconazol i blodet.
English: Refer to the prescribing information for velpatasvir/sofosbuvir/ voxilaprevir for more information.
Danish: Se ordineringsoplysningerne for velpatasvir/sofosbuvir/voxilapr evir for yderligere information.
English: No data are available to make a dose recommendation.
Danish: Data er ikke tilgængelige mhp doseringsanbefaling.
English: artemether/lumefantrine: Efavirenz Teva may reduce the amount of artemether/lumefantrine in your blood atovaquone/proguanil: Efavirenz Teva may reduce the amount of atovaquone/proguanil in your blood.
Danish: artemether/lumefantrin: Efavirenz Teva kan nedsætte mængden af artemether/lumefantrin i blodet.
English: AUC: ↑ 21% (↑ 10 to ↑ 34) Cmax: ↑ 14% (↑ 4 to ↑ 26) Cmin: ↑ 25% (↑ 7 to ↑ 46)
Danish: AUC: ↑ 21% (↑ 10 til ↑ 34) Cmax: ↑ 14% (↑ 4 til ↑ 26) Cmin: ↑ 25% (↑ 7 til ↑ 46) b
English: These drugs include: - antiarrhythmics of classes IA and III, - neuroleptics, antidepressive agents,
Danish: Disse lægemidler omfatter: - antiarytmika klasse IA og III - neuroleptika, antidepressiva - visse antibiotika inklusive lægemidler fra følgende klasser: makrolider, fluoroquinoloner,
English: Posaconazole/efavirenz (--/400 mg once daily)
Danish: Posaconazol/efavirenz (--/400 mg én gang dagligt)
English: Herbal preparations containing St. John's wort (Hypericum perforatum) due to the risk of decreased plasma concentrations and reduced clinical effects of efavirenz (see section 4.5).
Danish: Naturlægemidler som indeholder Prikbladet perikum (Hypericum perforatum) må ikke indtages samtidigt med indtagelse af efavirenz på grund af risiko for reduktion i plasmakoncentrationer samt reduceret klinisk effekt af efavirenz (se pkt.
English: N-monodesmethyl diltiazem: AUC: ↓ 37% (↓ 17 to ↓ 52) Cmax: ↓ 28% (↓ 7 to ↓ 44) Cmin: ↓ 37% (↓ 17 to ↓ 52)
Danish: N-monodesmethyl diltiazem: AUC: ↓ 37% (↓ 17 til ↓ 52) Cmax: ↓ 28% (↓ 7 til ↓ 44) Cmin: ↓ 37% (↓ 17 til ↓ 52)
English: Using an ITT analysis, the overall proportions of patients with HIV RNA <400 copies/mL and <50 copies/mL at Week 48 were 77% (33/43) and 70% (30/43), respectively.
Danish: Ved brug af ITTanalyse var andelen af patienter med hiv-RNA <400 kopier/ml og <50 kopier/ml ved uge 48 henholdsvis 77% (33/43) og 70% (30/43).
English: Famotidine/efavirenz (40 mg single dose/400 mg single dose)
Danish: Famotidin/efavirenz (40 mg enkeltdosis/400 mg enkeltdosis)
English: Hypromellose 6cP (HPMC 2910) Lactose monohydrate Titanium dioxide Macrogol/PEG 3350
Danish: Lactosemonohydrat 6cP (HPMC 2910) Titaniumdioxid
English: The increased efavirenz concentrations observed following administration of efavirenz with food may lead to an increase in frequency of adverse reactions (see sections 4.4 and 5.2).
Danish: Den øgede efavirenz-koncentration observeret efter administration af efavirenz sammen med mad kan medføre en øgede frekvens af bivirkninger (se pkt.
English: Integrase strand transfer inhibitor Raltegravir/efavirenz (400 mg single dose/ -)
Danish: Intergrasehæmmer af genoverførelse Raltegravir/efavirenz (400 mg enkeltdosis/ -)
English: Multipack (bundle) containing 90 film-coated tablets (3 packs of 30 x 1 film-coated tablet) in white opaque PVC/PVdC-aluminium or aluminium-aluminium perforated unit-dose blisters.
Danish: Multipack (bundt) med 90 filmovertrukne tabletter (3 pakninger à 30 x 1 filmovertrukket tablet) i hvide gennemsigtige PVC/PVdC-aluminium eller aluminium-aluminium perforerede enkeltdosisblisterpakninger.
English: AUC: ↑ 20% (↑ 8 to ↑ 34) Cmax: ↑ 21% (↑ 10 to ↑ 33)
Danish: AUC: ↑ 20% (↑ 8 til ↑ 34) Cmax: ↑ 21% (↑ 10 til ↑ 33)
English: CCR5 antagonist Maraviroc/efavirenz (100 mg twice daily/600 mg once daily)
Danish: CCR5-antagonist Maraviroc/efavirenz (100 mg to gange dagligt/600 mg én gang dagligt)
English: Lipid disorders should be managed as clinically appropriate
Danish: Tilstande med forhøjet lipid skal behandles som klinisk indiceret.
English: ACID-REDUCING AGENTS Aluminium hydroxidemagnesium hydroxidesimethicone antacid/efavirenz (30 ml single dose/400 mg single dose)
Danish: Aluminiumhydroxidmagnesiu mhydroxid-simeticon antacida/efavirenz (30 ml enkeltdosis/400 mg enkeltdosis)
English: Table 3: Efficacy results for studies ACTG 364 and 020 Responder rates (NC = Fa) Plasma HIV-RNA
Danish: Tabel 3: Effektresultater for undersøgelserne ACTG 364 og 020
English: Atovaquone and proguanil hydrochloride/efavirenz (250/100 mg single dose/600 mg once daily)
Danish: Atovaquon og proguanil hydrochlorid/efavirenz (250/100 mg enkeltdosis/600 mg én gang dagligt)
English: Lopinavir/ritonavir soft capsules or oral solution/ efavirenz
Danish: Lopinavir/ritonavir bløde kapsler eller oral opløsning/efavirenz
English: Study PACTG 1021 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with didanosine and emtricitabine in paediatric patients who were antiretroviral therapy naive.
Danish: Studie PACTG 1021 var et ikke-blindet studie til evaluering af efavirenz' farmakokinetik, sikkerhed, tolerabilitet og antivirale aktivitet i kombination med didanosin og emtricitabin hos antiretroviralnaive pædiatriske patienter.
English: AUC: ↓71% (↓67 to ↓74) Cmax: ↓51% (↓46 to ↓56) Cmin: ↓91% (↓88 to ↓92)
Danish: AUC: ↓ 71% (↓ 67 til ↓ 74) Cmax: ↓ 51% (↓ 46 til ↓ 56) Cmin: ↓ 91% (↓ 88 til ↓ 92)
English: Coadministration of glecaprevir/pibrentasvir with efavirenz is not recommended.
Danish: Samtidig administration af glecaprevir pibrentasvir med efavirenz anbefales ikke.
English: Plasma levels of efavirenz can be reduced by concomitant use of St. John's wort due to induction of drug-metabolising enzymes and/or transport proteins by St. John's wort.
Danish: Dette skyldes perikons induktion af lægemiddelmetaboliserende enzymer og/eller transportproteiner.
English: paranoia, psychosis†, suicide attempt, suicide ideation, catatonia*
Danish: Affektlabilitet, aggression, konfusion, eufori, hallucinationer, mani, paranoia, psykose†, suicidalforsøg, suicidaltanker, katatoni*
English: Multipack (carton) containing 90 film-coated tablets (3 packs of 30 x 1 film-coated tablet) in white opaque PVC/PVdC-aluminium or aluminium-aluminium perforated unit-dose blisters.
Danish: Multipack (æske) med 90 filmovertrukne tabletter (3 pakninger à 30 x 1 filmovertrukket tablet) i hvide gennemsigtige PVC/PVdC-aluminium eller aluminium-aluminium perforerede enkeltdosisblisterpakninger.
English: Common Pruritus
Danish: Almindelig Pruritus Ikke almindelig
English: Your doctor may give you a different anticonvulsant.
Danish: Lægen vil måske give dig en anden medicin mod krampeanfald.
English: Method of administration
Danish: Kontrolregime
English: If you are currently taking any of the following medicines (see also “Other medicines and Efavirenz Teva): Astemizole or terfenadine (used to treat allergy symptoms) Bepridil (used to treat heart disease) Cisapride (used to treat heartburn)
Danish: hvis du samtidigt tager et eller flere af følgende lægemidler (se også ”Brug af anden medicin sammen med Efavirenz Teva”): astemizol eller terfenadin (mod symptomer på allergi) bepridil (mod hjertesygdom) cisaprid (mod halsbrand) sekalealkaloider (f.eks. ergotamin, dihydroergotamin, ergonovin og methylergonovin) (mod migræne og klyngehovedpine)
English: Concomitant use of Ginkgo biloba extracts is not recommended (see section 4.5).
Danish: Samtidig anvendelse af Ginkgo biloba frarådes (se pkt.
English: Protease inhibitor : Elbasvir/grazoprevir
Danish: Proteasehæmmer: Elbasvir/grazoprevir
English: The mean Cmax of efavirenz in subjects with CYP2B6 *6/*6 genotype following the administration of 600 mg daily dose for 14 days was 2.25-fold the mean Cmax observed in subjects with CYP2B6 *1/*1 genotype.
Danish: Middel Cmax for efavirenz hos forsøgspersoner med genotype CYP2B6 *6/*6 efter administration af en daglig dosis på 600 mg i 14 dage var
English: Recommendation concerning co-administration with efavirenz immunosuppressants are not anticipated to affect exposure of efavirenz.
Danish: Disse immunsuppressiva forventes ikke at påvirke efavirenz' eksponering.
English: - itchy rash caused by a reaction to sunlight - liver failure, in some cases leading to death or liver transplant, has occurred with efavirenz.
Danish: - Leversvigt, som i nogle tilfælde kan føre til død eller levertransplantation, er forekommet sammen med efavirenz.
English: At baseline, median plasma HIV-1 RNA was 4.57 log10 copies/mL, median CD4+ cell count was 755 cells/mm3, and median CD4+ percentage was 30%.
Danish: Ved baseline var det mediane plasma hiv-RNA 4,57 log10-kopier/ml, median-CD4+ celletal var 755 celler/mm3, og median-CD4+ procent var 30%.
English: AUC12: ↓ 45% (↓ 38 to ↓ 51) Cmax: ↓ 51% (↓ 37 to ↓ 62)
Danish: AUC12: ↓ 45% (↓ 38 til ↓ 51) Cmax: ↓ 51% (↓ 37 til ↓ 62)
English: Clarithromycin/efavirenz (500 mg q12h/400 mg once daily)
Danish: Clarithromycin/efavirenz (500 mg q12h/400 mg én gang dagligt)
English: Five of these NNRTI-resistant isolates were found to have K103N or a valine-to-isoleucine substitution at position 108 (V108I) in RT. Three of the efavirenz treatment failure isolates tested remained sensitive to efavirenz in cell culture and were also sensitive to nevirapine and delavirdine.
Danish: (V108I) i RT. 3 af de testede efavirenz-behandlingssvigtisolater forblev følsomme over for efavirenz ved cellekultur og var også følsomme over for nevirapin og delavirdin.
English: Efavirenz Teva can reduce or increase the amount of anticonvulsant in your blood.
Danish: Efavirenz Teva kan nedsætte eller øge mængden af krampemedicin i blodet.
English: 30 x 1 film-coated tablet in white opaque PVC/PVdC-aluminium or aluminium-aluminium perforated unit-dose blisters.
Danish: 30 x 1 filmovertrukket tablet i hvide gennemsigtige PVC/PVdC-aluminium eller aluminiumaluminium perforeret enkeltdosis-blisterpakninger.
English: If you stop taking Efavirenz Teva When your Efavirenz Teva supply starts to run low, get more from your doctor or pharmacist.
Danish: Når din Efavirenz Teva er ved at slippe op, skal du hente mere hos din læge eller på apoteket.
English: Implant: Etonogestrel/efavirenz Decreased exposure of etonogestrel may be expected (CYP3A4 induction).
Danish: Der kan forventes nedsat eksponering for etonogestrel (CYP3A4-induktion).