FrancophonIA/ELRC3.0 huggingface dataset:
English: In the 40-week trial versus dulaglutide a weight loss of ≥5% and ≥10% was achieved for more subjects with Ozempic 0.5 mg (44% and 14%) compared with dulaglutide 0.75 mg (23% and 3%) and Ozempic 1 mg (up to 63% and 27%) compared with dulaglutide 1.5 mg (30% and 8%).
Slovenian: V 40-tedenskem preskušanju v primerjavi z dulaglutidom je ≥ 5-odstotno oz. ≥ 10-odstotno zmanjšanje telesne mase doseglo več prejemnikov zdravila Ozempic 0,5 mg (44 % oz. 14 %) kot prejemnikov 0,75 mg dulaglutida (23 % oz. 3 %) ter več prejemnikov zdravila Ozempic 1 mg (do 63 % oz. 27 %) kot prejemnikov 1,5 mg dulaglutida (30 % oz. 8 %).
English: SUSTAIN 5 - Ozempic vs. placebo both in combination with basal insulin In a 30-week double-blind placebo-controlled trial, 397 patients inadequately controlled with basal insulin with or without metformin were randomised to Ozempic 0.5 mg once weekly, Ozempic 1 mg once weekly or placebo.
Slovenian: SUSTAIN 5 - Zdravilo Ozempic v primerjavi s placebom, oba v kombinaciji z bazalnim insulinom V 30-tedenskem dvojno slepem, s placebom kontroliranem preskušanju so 397 bolnikov, nezadostno urejenih z bazalnim insulinom (z metforminom ali brez), randomizirali na 0,5 mg zdravila Ozempic enkrat na teden, 1 mg zdravila Ozempic enkrat na teden ali na placebo.
English: One ml solution for injection contains 1.34 mg semaglutide.
Slovenian: En mililiter raztopine za injiciranje vsebuje 1,34 mg semaglutida.
English: 1 mg in the dose counter must line up precisely with the dose pointer to ensure that you get a correct dose.
Slovenian: Oznaka za 1 mg na števcu odmerka mora biti natančno poravnana s kazalnikom odmerka, da boste zagotovo dobili pravilen odmerek.
English: No dose adjustment is required for patients with hepatic impairment.
Slovenian: Bolnikom z okvaro jeter odmerka ni treba prilagoditi.
English: Do not freeze Ozempic and do not use it if it has been frozen.
Slovenian: Zdravila Ozempic ne zamrzujte; če je bilo zmrznjeno, ga ne uporabite.
English: If pancreatitis is suspected, semaglutide should be discontinued; if confirmed, semaglutide should not be restarted.
Slovenian: Če se pankreatitis potrdi, se zdravljenja s semaglutidom ne sme znova uvesti.
English: It contains 4 mg of semaglutide, and you can only select doses of 1 mg.
Slovenian: Vsebuje 4 mg semaglutida in omogoča izključno 1-mg odmerek.
English: Semaglutide reduces blood glucose in a glucose dependent manner by stimulating insulin secretion and lowering glucagon secretion when blood glucose is high.
Slovenian: Semaglutid znižuje glukozo v krvi v odvisnosti od koncentracije glukoze, tako da spodbuja izločanje insulina in zmanjša izločanje glukagona, kadar je koncentracija glukoze v krvi velika.
English: Cardiovascular disease
Slovenian: Srčno-žilne bolezni
English: HR: 0.74 95% CI 0.58: 0.95
Slovenian: Ozempic placebo razmerje ogroženosti: 0.74 95 % IZ [0,58; 0,95]
English: No dose adjustment of paracetamol is necessary when administered with semaglutide.
Slovenian: Med uporabo s semaglutidom odmerka paracetamola ni treba prilagoditi.
English: • Never share your pen or your needles with other people.
Slovenian: • Svojega injekcijskega peresnika in igel si ne smete deliti z drugimi.
English: In a 56-week open-label trial, 813 patients on metformin alone (49%), metformin with sulfonylurea (45%) or other (6%) were randomised to Ozempic 1 mg or exenatide ER 2 mg once weekly.
Slovenian: V 56-tedenskem preskušanju z odprtim načrtom zdravljenja so 813 bolnikov, ki so prejemali samo metformin (49 %), metformin s sulfonilsečnino (45 %) ali kakšno drugo zdravljenje (6 %),
English: Ozempic is to be injected subcutaneously in the abdomen, in the thigh or in the upper arm.
Slovenian: Zdravilo Ozempic je treba injicirati subkutano v trebuh, stegno ali nadlaket.
English: 1 mg selected
Slovenian: izbran je odmerek 1 mg
English: In the phase 3a trials, mean increases of 1 to 6 beats per minute (bpm) from a baseline of 72 to 76 bpm were observed in subjects treated with Ozempic.
Slovenian: V preskušanjih faze 3a so pri osebah, ki so prejemale zdravilo Ozempic, zabeležili povprečno povečanje za 1 do 6 utripov na minuto od izhodiščne frekvence, ki je bila od 72 do 76 utripov na minuto.
English: Talk to your doctor if you have any questions or concerns.
Slovenian: Če imate kakšna vprašanja ali vas kaj skrbi, se posvetujte z zdravnikom.
English: Prepare your pen with a new needle
Slovenian: Pripravite injekcijski peresnik z novo injekcijsko iglo
English: Cardiovascular death Non-fatal stroke Non-fatal myocardial infarction
Slovenian: Možganska kap brez smrtnega izida Miokardni infarkt brez smrtnega izida razmerje ogroženosti
English: How to identify a blocked or damaged needle - If 0 does not appear in the dose counter after continuously pressing the dose button, you may have used a blocked or damaged needle.
Slovenian: - Če se po večkratnem pritiskanju potisnega gumba na števcu odmerka ne pokaže 0, je igla lahko zamašena ali poškodovana.
English: Instructions on how to use Ozempic 1 mg solution for injection in pre-filled pen Please read these instructions carefully before using your Ozempic pre-filled pen.
Slovenian: Pred uporabo injekcijskega peresnika Ozempic natančno preberite ta navodila.
English: Always dispose of the needle after each injection to ensure convenient injections and prevent blocked needles.
Slovenian: Iglo zavrzite po vsakem injiciranju, da zagotovite nemoteno injiciranje in da preprečite mašenje igle.
English: Ozempic 0.5 mg vs dulaglutide 0.75 mg c Ozempic 1 mg vs dulaglutide 1.5 mg
Slovenian: Ozempic 1 mg dulaglutid 0,75 mg dulaglutid 1,5 mg
English: Combining a sulfonylurea or an insulin with this medicine might increase the risk of getting low blood sugar levels (hypoglycaemia).
Slovenian: Hipoglikemija Sočasna uporaba sulfonilsečnine ali insulina skupaj s tem zdravilom lahko poveča tveganje za prenizko koncentracijo krvnega sladkorja (hipoglikemijo).
English: 1 pen and 4 disposable needles (4 doses)
Slovenian: 1 injekcijski peresnik in 4 igle za enkratno uporabo (4 odmerki)
English: Semaglutide compared to placebo lowered fasting triglyceride and very low density lipoproteins (VLDL) cholesterol concentrations by 12% and 21%, respectively.
Slovenian: Lipidi na tešče in po obrokih Semaglutid je v primerjavi s placebom znižal koncentracijo trigliceridov na tešče za 12 % in holesterola v lipoproteinih zelo majhne gostote (VLDL - Very Low Density Lipoproteins) na tešče za
English: The pen is for use by one person only.
Slovenian: Injekcijski peresnik je namenjen izključno za uporabo pri enem samem bolniku.
English: 0.5 mg in the dose counter must line up precisely with the dose pointer to ensure that you get a correct dose.
Slovenian: Oznaka za 0,5 mg na števcu odmerka mora biti natančno poravnana s kazalnikom odmerka, da boste zagotovo dobili pravilen odmerek.
English: If necessary, clean it with a mild detergent on a moistened cloth.
Slovenian: Po potrebi ga očistite s krpo,
English: The trial compared 0.5 mg of Ozempic to 0.75 mg of dulaglutide and 1 mg of Ozempic to 1.5 mg of dulaglutide.
Slovenian: V preskušanju so primerjali 0,5 mg zdravila Ozempic z 0,75 mg dulaglutida in 1 mg zdravila Ozempic z 1,5 mg dulaglutida.
English: Please see section 4 for the warning signs of low blood sugar levels.
Slovenian: Za opozorilne znake prenizke koncentracije krvnega sladkorja glejte poglavje 4.
English: A drop of solution may appear at the needle tip.
Slovenian: Na konici igle se lahko pokaže kapljica raztopine.
English: Ozempic pre-filled pen and needle (example)
Slovenian: Napolnjen injekcijski peresnik Ozempic in injekcijska igla (primer)
English: Semaglutide did not change the overall exposure of atorvastatin following a single dose administration of atorvastatin (40 mg).
Slovenian: Semaglutid po enkratnem odmerku atorvastatina (40 mg) ni spremenil celotne izpostavljenosti atorvastatinu.
English: This may prevent blocked needles, contamination, infection, leakage of solution and inaccurate dosing.
Slovenian: To lahko prepreči zamašitev igle, kontaminacijo, okužbo, iztekanje raztopine in netočno odmerjanje.
English: Semaglutide did not prolong QTc intervals at supra-therapeutic dose levels (up to 1.5 mg at steady state).
Slovenian: Semaglutid v odmerkih, večjih od terapevtskih (do 1,5 mg v stanju dinamičnega ravnovesja), ni podaljšal intervala QTc.
English: MARKETING AUTHORISATION NUMBERS EU/1/17/1251/003 1 pen and 4 disposable needles EU/1/17/1251/004 3 pens and 12 disposable needles
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/17/1251/003 1 injekcijski peresnik in 4 igle za enkratno uporabo EU/1/17/1251/004 3 injekcijski peresniki in 12 igel za enkratno uporabo
English: Semaglutide did not change the overall exposure or Cmax of digoxin following a single dose of digoxin (0.5 mg).
Slovenian: Semaglutid po enkratnem odmerku digoksina (0,5 mg) ni spremenil celotne izpostavljenosti digoksinu ali njegove Cmax.
English: MARKETING AUTHORISATION NUMBERS EU/1/17/1251/005 1 pen and 4 disposable needles EU/1/17/1251/006 3 pens and 12 disposable needles
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/17/1251/005 1 injekcijski peresnik in 4 igle za enkratno uporabo EU/1/17/1251/006 3 injekcijski peresniki in 12 igel za enkratno uporabo
English: 0.25 mg in the dose counter must line up precisely with the dose pointer to ensure that you get a correct dose.
Slovenian: Oznaka za 0,25 mg na števcu odmerka mora biti natančno poravnana s kazalnikom odmerka, da boste zagotovo dobili pravilen odmerek.
English: This reduces the risk of blocked needles, contamination, infection and inaccurate dosing.
Slovenian: Tako boste zmanjšali tveganje za zamašitev igle, kontaminacijo, okužbo in netočno odmerjanje.
English: This was supported by a semaglutide-induced suppression of appetite in the fasting state as well as postprandially, improved control of eating, less food cravings and a relative lower preference for high fat food.
Slovenian: Semaglutid je v primerjavi s placebom zmanjšal energijski vnos 3 zaporednih ad libitum obrokov za 18-35 %, kar je bilo doseženo s semaglutidom izzvanim zmanjšanjem apetita na tešče in po obrokih, boljšim obvladovanjem uživanja hrane, manjšim hlepenjem po hrani in razmeroma manjšo željo po zelo mastni hrani.
English: Semaglutide 0.5 mg
Slovenian: Ozempic 0,5 mg
English: Hold the dose button down until the dose counter shows 0.
Slovenian: Držite potisni gumb pritisnjen, dokler števec odmerka ne pokaže 0.
English: Other secondary endpoints All cause death
Slovenian: Smrt zaradi vseh vzrokov
English: Talk to your doctor, pharmacist or nurse before using this medicine.
Slovenian: Pred začetkom uporabe zdravila se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
English: • gas (flatulence)
Slovenian: • vetrovi (napenjanje)
English: Ozempic contains the active substance semaglutide.
Slovenian: Zdravilo Ozempic vsebuje učinkovino semaglutid.
English: Hazard Ratio (95% CI)
Slovenian: (95% IZ)
English: Patients (%) achieving HbA1c <7% FPG (mmol/L)
Slovenian: Bolniki (%), ki so dosegli HbA1c Glukoza v plazmi na tešče (mmol/L)
English: If so, the full dose will not be delivered.
Slovenian: V tem primeru niste injicirali celotnega odmerka.
English: It contains 2 mg of semaglutide, and you can only select doses of 0.25 mg.
Slovenian: Vsebuje 2 mg semaglutida in omogoča izključno 0,25-mg odmerek.
English: In SUSTAIN 6 (see subsection Cardiovascular disease) 867 patients were on premix insulin (with or without OAD(s)) at baseline.
Slovenian: Kombinacija s pripravljeno mešanico insulina z/brez 1 ali 2 peroralnima antidiabetikoma V preskušanju SUSTAIN 6 (glejte podpoglavje Srčno-žilne bolezni) je 867 bolnikov izhodiščno uporabljalo pripravljeno mešanico insulina (z enim ali več peroralnih antidiabetičnih zdravil ali brez njih).
English: If you use this medicine in combination with a sulphonylurea or insulin, low blood sugar (hypoglycaemia) may occur which may reduce your ability to concentrate.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Če uporabljate to zdravilo v kombinaciji s sulfonilsečnino ali insulinom, se lahko pojavi prenizek krvni sladkor (hipoglikemija), ki vam lahko zmanjša sposobnost za zbranost.
English: Semaglutide lowers the fasting and postprandial glucagon concentrations.
Slovenian: Semaglutid zniža koncentracijo glukagona na tešče in postprandialno.
English: Diabetic retinopathy
Slovenian: Diabetična retinopatija
English: It contains 2 mg of semaglutide, and you can only select doses of 0.5 mg.
Slovenian: Vsebuje 2 mg semaglutida in omogoča izključno 0,5-mg odmerek.
English: During hypoglycaemia, semaglutide diminishes insulin secretion and does not impair glucagon secretion.
Slovenian: Med hipoglikemijo semaglutid zmanjša izločanje insulina, ne zmanjša pa izločanja glukagona.
English: The principal mechanism of protraction is albumin binding, which results in decreased renal clearance and protection from metabolic degradation.
Slovenian: Glavni mehanizem podaljšanja razpolovnega časa je vezava na albumine, ki zmanjša ledvični očistek učinkovine in jo zaščiti pred presnovno razgradnjo, poleg tega pa semaglutid stabilizira tudi proti razgradnji z encimom DPP-4.
English: Semaglutide delays the rate of gastric emptying as assessed by paracetamol pharmacokinetics during a standardised meal test. Paracetamol AUC0-60min and Cmax were decreased by 27% and 23%, respectively, following concomitant use of semaglutide 1 mg.
Slovenian: Po sočasni uporabi z 1 mg semaglutida se je AUC0-60min paracetamola zmanjšala za 27 % in njegova Cmax za 23 %.
English: Always remove the injection needle after each injection and store the pen without a needle attached.
Slovenian: Iglo morate po vsakem injiciranju odstraniti in injekcijski peresnik shraniti brez nameščene igle.
English: The proportion of patients tested positive for anti-semaglutide antibodies at any time point post-baseline was low (1−2%) and no patients had anti-semaglutide neutralising antibodies or anti-semaglutide antibodies with endogenous GLP-1 neutralising effect at end-of-trial.
Slovenian: Noben bolnik ob koncu preskušanja ni imel nevtralizirajočih protiteles proti semaglutidu ali protiteles proti semaglutidu, ki bi nevtralizirala učinek endogenega GLP-1.
English: Exenatide ER 2 mg
Slovenian: 2 mg
English: Ozempic 1 mg solution for injection: Each pre-filled pen contains 3 ml of solution, delivering 4 doses of 1 mg.
Slovenian: Ozempic 1 mg raztopina za injiciranje: en napolnjen injekcijski peresnik vsebuje 3 ml raztopine in omogoča odmerjanje 4 odmerkov po 1 mg.
English: Ozempic 1 mg solution for injection
Slovenian: Ozempic 1 mg raztopina za injiciranje
English: You may get side effects such as feeling sick (nausea).
Slovenian: Pojavijo se vam lahko neželeni učinki, na primer slabost (navzea).
English: Change from baseline at week 30 Difference from placebo [95% CI]
Slovenian: Sprememba od izhodišča v 40. tednu -1,5 Razlika v primerjavi z dulaglutidom [95 % IZ]
English: Diabetic retinopathy complications
Slovenian: Zapleti diabetične retinopatije
English: LIST OF EXCIPIENTS disodium phosphate dihydrate, propylene glycol, phenol, hydrochloric acid/sodium hydroxide (for pH adjustment), water for injections
Slovenian: SEZNAM POMOŽNIH SNOVI natrijev hidrogenfosfat dihidrat, propilenglikol, fenol, klorovodikovo kislino (za uravnavanje pH), natrijev hidroksid (za uravnavanje pH) in vodo za injekcije.
English: STATEMENT OF ACTIVE SUBSTANCE Each dose (0.74 ml) contains 1 mg semaglutide (1.34 mg/ml),
Slovenian: NAVEDBA ENE ALI VEČ UČINKOVIN En odmerek (0,74 ml) vsebuje 1 mg semaglutida (1,34 mg/ml),
English: • bloating of the stomach
Slovenian: • bolečine v trebuhu
English: Use semaglutide once a week Write the weekday you choose to inject I injected my weekly dose on the below dates subcutaneous use
Slovenian: Vpišite dan v tednu, ki ste ga izbrali za injiciranje:
English: 0.25 mg selected
Slovenian: izbran je odmerek 0,25 mg
English: Start by checking your pen to make sure that it contains Ozempic 0.25 mg, then look at the illustrations below to get to know the different parts of your pen and needle.
Slovenian: Začnite s preverjanjem injekcijskega peresnika: prepričajte se, da vsebuje zdravilo Ozempic 0,25 mg. Nato si oglejte spodnje ilustracije, da se boste seznanili z deli injekcijskega peresnika in igel.
English: • indigestion
Slovenian: • bruhanje
English: NAME OF THE MEDICINAL PRODUCT Ozempic 0.25 mg solution for injection in pre-filled pen Ozempic 0.5 mg solution for injection in pre-filled pen Ozempic 1 mg solution for injection in pre-filled pen
Slovenian: Ozempic 0,25 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku Ozempic 0,5 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku
English: The dose selector clicks differently when turned forwards, backwards or past 0.25 mg. Do not count the pen clicks.
Slovenian: Le števec in kazalnik odmerka kažeta, da ste izbrali 0,25 mg. Izbirnik odmerka klika z drugačnim zvokom, ko ga obračate naprej, nazaj ali mimo odmerka 0,25 mg. Ne štejte klikov injekcijskega peresnika.
English: HbA1c at baseline was 8.8%, 8.9% and 8.9% for Ozempic 0.5 mg, Ozempic 1 mg, and placebo, respectively.
Slovenian: Izhodiščno je bil HbA1c v skupini z 0,5 mg zdravila Ozempic 8,8 %, z 1 mg zdravila Ozempic 8,9 % in s placebom 8,9 %.
English: Mechanistic evaluations indicated that the embryotoxicity involved a GLP-1 receptor mediated impairment of the nutrient supply to the embryo across the rat yolk sac.
Slovenian: Proučevanje mehanizma je pokazalo, da embriotoksičnost vključuje preko receptorjev GLP-1
English: Semaglutide lowered high blood glucose concentrations by stimulating insulin secretion and lowering glucagon secretion in a glucose dependent manner.
Slovenian: Od glukoze odvisno izločanje insulina in glukagona Semaglutid je znižal povišano koncentracijo glukoze v krvi s stimulacijo izločanja insulina in zmanjšanjem sekrecije glukagona v odvisnosti od koncentracije glukoze.
English: Each pen contains 3 ml solution, delivering 4 doses of 1 mg.
Slovenian: En injekcijski peresnik vsebuje 3 ml raztopine in omogoča 4 odmerke po 1 mg.
English: Always remove the needle from your pen immediately after each injection.
Slovenian: Po vsakem injiciranju iglo nemudoma odstranite z injekcijskega peresnika.
English: One pre-filled pen contains 4 mg semaglutide in 3 ml solution.
Slovenian: En napolnjeni injekcijski peresnik vsebuje 4 mg semaglutida v 3 ml raztopine.
English: Always use the dose counter and the dose pointer to see that 1 mg has been selected before injecting this medicine.
Slovenian: Pred injiciranjem zdravila s števcem in kazalnikom odmerka vedno preverite, da ste izbrali odmerek 1 mg.
English: Start by checking your pen to make sure that it contains Ozempic 0.5 mg, then look at the illustrations below to get to know the different parts of your pen and needle.
Slovenian: Začnite s preverjanjem injekcijskega peresnika: prepričajte se, da vsebuje zdravilo Ozempic 0,5 mg. Nato si oglejte spodnje ilustracije, da se boste seznanili z deli injekcijskega peresnika in igel.
English: One pre-filled pen contains 2 mg semaglutide in 1.5 ml solution.
Slovenian: En napolnjen injekcijski peresnik vsebuje 2 mg semaglutida v 1,5 ml raztopine.
English: Age had no effect on the pharmacokinetics of semaglutide based on data from phase 3a studies including patients of 20-86 years of age.
Slovenian: Po podatkih študij faze 3a, ki so zajele bolnike v starosti od 20 do 86 let, starost ni vplivala na farmakokinetiko semaglutida.
English: SN:
Slovenian: PC:
English: 1 pre-filled pen and 4 disposable NovoFine Plus needles
Slovenian: 1 napolnjen injekcijski peresnik in 4 igle NovoFine Plus za enkratno uporabo.
English: In a 30-week open-label comparator trial 1,089 patients were randomised to Ozempic 0.5 mg once weekly, Ozempic 1 mg once weekly, or insulin glargine once-daily on a background of metformin (48%) or metformin and sulfonylurea (51%).
Slovenian: SUSTAIN 4 - Zdravilo Ozempic v primerjavi z insulinom glargin, oba v kombinaciji z 1 ali 2 peroralnima antidiabetičnima zdraviloma (metforminom ali metforminom in sulfonilsečnino) V 30-tedenskem primerjalnem preskušanju z odprtim načrtom zdravljenja so 1.089 bolnikov randomizirali na 0,5 mg zdravila Ozempic enkrat na teden ali 1 mg zdravila Ozempic enkrat na teden ali na insulin glargin enkrat na dan, vse ob osnovnem zdravljenju z metforminom (48 %) ali metforminom in sulfonilsečnino (51 %).
English: Start by checking your pen to make sure that it contains Ozempic 1 mg, then look at the illustrations below to get to know the different parts of your pen and needle.
Slovenian: Začnite s preverjanjem injekcijskega peresnika: prepričajte se, da vsebuje zdravilo Ozempic 1 mg. Nato si oglejte spodnje ilustracije, da se boste seznanili z deli injekcijskega peresnika in igel.
English: Ozempic 0.25 mg solution for injection: Each pre-filled pen contains 1.5 ml of solution, delivering 4 doses of 0.25 mg.
Slovenian: Ozempic 0,25 mg raztopina za injiciranje: en napolnjen injekcijski peresnik vsebuje 1,5 ml raztopine in omogoča odmerjanje 4 odmerkov po 0,25 mg.
English: No episodes of severe hypoglycaemia were observed when semaglutide was used as monotherapy.
Slovenian: Med uporabo semaglutida v monoterapiji niso opazili hudih hipoglikemij.
English: STATEMENT OF ACTIVE SUBSTANCE Each dose (0.37 ml) contains 0.5 mg semaglutide (1.34 mg/ml),
Slovenian: NAVEDBA ENE ALI VEČ UČINKOVIN En odmerek (0,37 ml) vsebuje 0,5 mg semaglutida (1,34 mg/ml),
English: -5.1 [-6.1, -4.0]a p <0.0001 (2-sided) for superiority
Slovenian: -5,1 [-6,1; -4,0]a p < 0,0001 (2-stransko) za superiornost
English: Ozempic 0.25 mg solution for injection
Slovenian: Ozempic 0,25 mg raztopina za injiciranje
English: Name and address of the manufacturer responsible for batch release
Slovenian: Ime in naslov izdelovalca, odgovornega za sproščanje serij Novo Nordisk A/S
English: STATEMENT OF ACTIVE SUBSTANCE Each dose (0.19 ml) contains 0.25 mg semaglutide (1.34 mg/ml),
Slovenian: NAVEDBA ENE ALI VEČ UČINKOVIN En odmerek (0,19 ml) vsebuje 0,25 mg semaglutida (1,34 mg/ml),
English: This reduces the risk of blocked needles, contamination, infection, leakage of solution and inaccurate dosing.
Slovenian: Tako boste zmanjšali tveganje za zamašitev igle, kontaminacijo, okužbo, iztekanje raztopine in netočno odmerjanje.
English: 0.5 mg selected
Slovenian: izbran je odmerek 0,5 mg
English: In a 56-week active-controlled double-blind trial, 1,231 patients were randomised to Ozempic 0.5 mg once weekly, Ozempic 1 mg once weekly or sitagliptin 100 mg once daily, all in combination with metformin (94%) and/or thiazolidinediones (6%).
Slovenian: SUSTAIN 2 - Zdravilo Ozempic v primerjavi s sitagliptinom, oba v kombinaciji z 1 ali 2 peroralnima antidiabetičnima zdraviloma (metforminom in/ali tiazolidindioni) V 56-tedenskem, z učinkovino kontroliranem, dvojno slepem preskušanju so 1.231 bolnikov randomizirali na 0,5 mg zdravila Ozempic enkrat na teden, 1 mg zdravila Ozempic enkrat na teden ali na 100 mg sitagliptina enkrat na dan, vse v kombinaciji z metforminom (94 %) in/ali tiazolidindioni
English: The dose selector clicks differently when turned forwards, backwards or past 1 mg. Do not count the pen clicks.
Slovenian: Le števec in kazalnik odmerka kažeta, da ste izbrali 1 mg. Izbirnik odmerka klika z drugačnim zvokom, ko ga obračate naprej, nazaj ali mimo odmerka 1 mg. Ne štejte klikov injekcijskega peresnika.
English: Nervous system disorders
Slovenian: Bolezni živčevja omotica dizgevzija
English: -3.6c [-4.3, -2.8]a p <0.0001 (2-sided) for superiority b
Slovenian: -3,6c [-4,3; -2,8]a ap < 0,0001 (2-stransko) za superiornost b
English: The dose selector clicks differently when turned forwards, backwards or past 0.5 mg. Do not count the pen clicks.
Slovenian: Le števec in kazalnik odmerka kažeta, da ste izbrali 0,5 mg. Izbirnik odmerka klika z drugačnim zvokom, ko ga obračate naprej, nazaj ali mimo odmerka 0,5 mg. Ne štejte klikov injekcijskega peresnika.