FrancophonIA/ELRC3.0 huggingface dataset:
English: • injection site reactions - such as bruising, pain, irritation, itching and rash.
Slovenian: • reakcije na mestu injiciranja, npr. podplutbe, bolečina, draženje, srbenje in izpuščaj
English: In embryo-foetal development studies in rats, semaglutide caused embryotoxicity below clinically relevant exposures.
Slovenian: V študijah embriofetalnega razvoja pri podganah je bil semaglutid embriotoksičen ob izpostavljenostih, manjših od klinično pomembnih.
English: Semaglutide is not recommended for use in patients with end-stage renal disease (see section 5.2).
Slovenian: Zdravljenje s semaglutidom ni priporočljivo pri bolnikih s končno odpovedjo ledvic (glejte poglavje 5.2).
English: After 4 weeks the dose should be increased to 0.5 mg once weekly.
Slovenian: Po 4 tednih je treba odmerek povečati na 0,5 mg enkrat na teden.
English: Discontinuation due to an adverse event
Slovenian: Prekinitev zdravljenja zaradi neželenega učinka
English: Hypoglycaemia defined as severe (requiring the assistance of another person) or symptomatic in combination with a blood glucose <3.1 mmol/L
Slovenian: povečana koncentracija amilaze, zmanjšanje telesne mase a) Hipoglikemija, opredeljena kot huda (zahtevala je pomoč druge osebe) ali simptomatska, v kombinaciji s koncentracijo glukoze v krvi < 3,1 mmol/l.
English: Never try to put the inner needle cap back on the needle.
Slovenian: Na iglo nikoli ne poskušajte znova namestiti notranjega pokrovčka, ker se z iglo lahko zbodete.
English: After selecting a new dosing day, once-weekly dosing should be continued.
Slovenian: Po izbiri novega dneva za injiciranje zdravila je treba nadaljevati z odmerjanjem enkrat na teden.
English: Sitagliptin 100 mg
Slovenian: 100 mg
English: Exposure of ethinylestradiol was not affected; an increase of 20% was observed for levonorgestrel exposure at steady state.
Slovenian: Izpostavljenost etinilestradiolu se ni spremenila, v stanju dinamičnega ravnovesja pa so opazili za 20 % večjo izpostavljenost levonorgestrelu.
English: Only use the medicine in this pen as prescribed.
Slovenian: Zdravilo v tem peresniku uporabite izključno v skladu s predpisom zdravnika.
English: If this happens you might not get the intended effect of this medicine.
Slovenian: V tem primeru morda ne boste deležni želenega učinka tega zdravila.
English: Overdoses of up to 4 mg in a single dose, and up to 4 mg in a week have been reported in clinical trials.
Slovenian: V kliničnih preskušanjih so poročali o prevelikih odmerkih do 4 mg v enkratnem odmerku in do 4 mg v enem tednu.
English: • Do not drop your pen or knock it against hard surfaces.
Slovenian: • Pazite, da vam injekcijski peresnik ne pade in da z njim ne udarite ob trdo površino.
English: Marketing Authorisation Holder and Manufacturer Novo Nordisk A/S
Slovenian: Imetnik dovoljenja za promet z zdravilom in izdelovalec Novo Nordisk A/S
English: When the pen is empty, throw it away without a needle on as instructed by your doctor, nurse, pharmacist or local authorities.
Slovenian: Ko injekcijskega peresnika ne potrebujete več, ga zavrzite brez nameščene igle, kot vam je to naročil zdravnik, medicinska sestra, farmacevt ali kot zahtevajo lokalni predpisi.
English: If the dose counter stops before 1 mg, there is not enough solution left for a full dose of 1 mg.
Slovenian: Če se števec odmerka ustavi pred 1 mg, v injekcijskem peresniku ni več dovolj raztopine za polni odmerek 1 mg.
English: In 2-year carcinogenicity studies in rats and mice, semaglutide caused thyroid C-cell tumours at clinically relevant exposures.
Slovenian: V 2-letnih študijah kancerogenosti pri podganah in miših je semaglutid ob klinično pomembni izpostavljenosti povzročil tumorje parafolikularnih celic ščitnice.
English: Experience with the use of semaglutide in patients with severe renal impairment is limited.
Slovenian: Izkušenj z uporabo semaglutida pri bolnikih s hudo okvaro ledvic je malo.
English: If your pen is already in use, go to step 3 ‘Select your dose'.
Slovenian: Če je injekcijski peresnik že bil uporabljen, glejte poglavje 3, "Izbira odmerka".
English: Semaglutide delays gastric emptying and has the potential to impact the rate of absorption of concomitantly administered oral medicinal products.
Slovenian: Semaglutid upočasni praznjenje želodca in tako lahko vpliva na hitrost absorpcije sočasno uporabljenih peroralnih zdravil.
English: Use of GLP-1 receptor agonists may be associated with gastrointestinal adverse reactions.
Slovenian: Uporabo agonistov receptorjev GLP-1 lahko spremljajo neželeni učinki na prebavilih.
English: In patients with type 2 diabetes, semaglutide resulted in the following relative reductions in glucagon compared to placebo: fasting glucagon (8-21%), postprandial glucagon response (14-15%) and mean 24 hour glucagon concentration (12%).
Slovenian: Pri bolnikih s sladkorno boleznijo tipa 2 je semaglutid v primerjavi s placebom povzročil naslednja relativna znižanja koncentracije glukagona: na tešče za 8-21 %, postprandialnega odziva glukagona za 14-15 % in povprečne 24-urne koncentracije glukagona za 12 %.
English: Semaglutide caused a minor delay of early postprandial gastric emptying, thereby reducing the rate at which glucose appears in the circulation postprandially.
Slovenian: Semaglutid je povzročil manjšo zakasnitev zgodnjega postprandialnega praznjenja želodca, s čimer se je zmanjšala hitrost postprandialnega pojavljanja glukoze v krvnem obtoku.
English: Semaglutide had a beneficial effect on plasma lipids, lowered systolic blood pressure and reduced inflammation in clinical studies.
Slovenian: Semaglutid je v kliničnih študijah ugodno vplival na lipide v plazmi, znižal je sistolični krvni tlak in zmanjšal vnetje.
English: Ozempic is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise
Slovenian: Zdravilo Ozempic je namenjeno zdravljenju odraslih z nezadostno urejeno sladkorno boleznijo tipa 2
English: The patient should be advised to discard the injection needle after each injection and store the pen without an injection needle attached.
Slovenian: Bolnika opozorite, naj po vsakem injiciranju zdravila injekcijsko iglo zavrže in naj injekcijski peresnik shranjuje brez nameščene igle.
English: If it shows 0.5, at least 0.5 mg is left in your pen.
Slovenian: Če števec odmerka kaže 0,5, je v vašem injekcijskem peresniku vsaj še 0,5 mg.
English: Semaglutide 0.25 mg is not a maintenance dose.
Slovenian: 0,25-mg odmerek semaglutida ni vzdrževalni odmerek.
English: (AUC0-5h) was not affected.
Slovenian: Celotna izpostavljenost paracetamolu (AUC0-5h) se ni spremenila.
English: In developmental toxicity studies in rabbits and cynomolgus monkeys, increased pregnancy loss and slightly increased incidence of foetal abnormalities were observed at clinically relevant exposures.
Slovenian: V študijah razvojne toksičnosti pri kuncih in opicah cynomolgus so ob klinično pomembnih izpostavljenostih opažali pogostejšo prekinitev brejosti in rahlo večjo pojavnost nepravilnosti pri plodovih.
English: Increased heart rate
Slovenian: Povečanje srčne frekvence
English: The total numbers of cardiovascular deaths, non-fatal myocardial infarctions and non-fatal strokes were 90, 111, and 71, respectively, including 44 (2.7%), 47 (2.9%), and 27 (1.6%), respectively, with semaglutide (figure 4).
Slovenian: Skupno število srčno-žilnih smrti je bilo 90 (s semaglutidom 44 [2,7 %]), miokardnih infarktov brez smrtnega izida 111 (s semaglutidom 47 [2,9 %]) in možganskih kapi brez smrtnega izida 71 (s semaglutidom 27 [1,6 %]) (slika 4).
English: In patients with type 2 diabetes, the mean steady state concentrations following subcutaneous administration of 0.5 mg and 1 mg semaglutide were approximately 16 nmol/L and 30 nmol/L, respectively.
Slovenian: Pri bolnikih s sladkorno boleznijo tipa 2 je bila povprečna koncentracija v stanju dinamičnega ravnovesja po subkutani uporabi 0,5 mg približno 16 nmol/l in 1 mg približno 30 nmol/l.
English: Do not stop using this medicine without talking to your doctor.
Slovenian: Če ste prenehali uporabljati zdravilo Ozempic Ne prenehajte uporabljati tega zdravila, ne da bi se prej posvetovali z zdravnikom.
English: Experience with the use of Semaglutide in patients with severe hepatic impairment is limited.
Slovenian: Izkušenj z uporabo semaglutida pri bolnikih s hudo okvaro jeter je malo.
English: If the dose counter stops before 0.5 mg, there is not enough solution left for a full dose of 0.5 mg.
Slovenian: Če se števec odmerka ustavi pred 0,5 mg, v injekcijskem peresniku ni več dovolj raztopine za polni odmerek 0,5 mg.
English: If it shows 1, at least 1 mg is left in your pen.
Slovenian: Če števec odmerka kaže 1, je v vašem injekcijskem peresniku vsaj še 1 mg.
English: Prior to excretion, semaglutide is extensively metabolised through proteolytic cleavage of the peptide backbone and sequential beta-oxidation of the fatty acid sidechain.
Slovenian: Presnova/Biotransformacija Pred izločanjem se semaglutid obsežno presnovi s proteolitičnim razcepom peptidne hrbtenice in nadaljnjo beta-oksidacijo stranske maščobnokislinske verige.
English: Semaglutide is not anticipated to decrease the effect of oral contraceptives as semaglutide did not change the overall exposure of ethinylestradiol and levonorgestrel to a clinically relevant degree when an oral contraceptive combination medicinal product (0.03 mg ethinylestradiol/0.15 mg levonorgestrel) was co-administered with semaglutide.
Slovenian: Semaglutid namreč ni klinično pomembno spremenil celotne izpostavljenosti etinilestradiolu in levonorgestrelu, če je bil sočasno s semaglutidom uporabljen peroralni kontraceptiv (0,03 mg etinilestradiola/0,15 mg levonorgestrela).
English: SUSTAIN 3 - Ozempic vs. exenatide ER both in combination with metformin or metformin with sulfonylurea
Slovenian: SUSTAIN 3 - Zdravilo Ozempic v primerjavi z eksenatidom ER, oba v kombinaciji z metforminom ali z metforminom in sulfonilsečnino
English: Diabetic retinopathy complications is a composite of: retinal photocoagulation, treatment with intravitreal agents, vitreous haemorrhage, diabetes-related blindness (uncommon).
Slovenian: b) Zapleti diabetične retinopatije obsegajo: fotokoagulacijo mrežnice, zdravljenje z intravitrealnimi sredstvi, krvavitev v steklovino, s sladkorno boleznijo povezano slepoto (občasen zaplet).
English: Figure 3 Kaplan-Meier plot of time to first occurrence of the composite outcome: cardiovascular death, non-fatal myocardial infarction or non-fatal stroke (SUSTAIN 6)
Slovenian: Kaplan-Meierjev prikaz časa do prvega pojava sestavljenega izida: srčno-žilne smrti, miokardnega infarkta brez smrtnega izida ali možganske kapi brez smrtnega izida (SUSTAIN 6)
English: In a long-term trial in subjects with cardiovascular risk factors, 16% of Ozempic-treated subjects had an increase in heart rate of >10 bpm compared to 11% of subjects on placebo after 2 years of treatment.
Slovenian: V dolgoročnem preskušanju pri osebah s srčno-žilnimi dejavniki tveganja je imelo po 2 letih zdravljenja srčno frekvenco večjo za > 10 utripov na minuto 16 % preiskovancev, ki so prejemali zdravilo Ozempic, in 11 % tistih, ki so prejemali placebo.
English: This medicine contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially ‘sodium-free'.
Slovenian: To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na odmerek, kar v bistvu pomeni "brez natrija".
English: An additional trial including 1,201 patients was conducted to compare the efficacy and safety of Ozempic 0.5 mg and 1 mg once weekly to dulaglutide 0.75 mg and 1.5 mg once weekly, respectively.
Slovenian: Dodatno preskušanje, ki je zajelo 1.201 bolnika, so izvedli za primerjavo učinkovitosti in varnosti zdravila Ozempic 0,5 mg enkrat na teden z 0,75 mg dulaglutida enkrat na teden ter zdravila Ozempic 1 mg enkrat na teden z 1,5 mg dulaglutida enkrat na teden.
English: Renal impairment did not impact the pharmacokinetics of semaglutide in a clinically relevant manner.
Slovenian: Okvara ledvic ni klinično pomembno vplivala na farmakokinetiko semaglutida.
English: If you use more Ozempic than you should, talk to your doctor straight away.
Slovenian: Če ste uporabili večji odmerek zdravila Ozempic, kot bi smeli Če ste uporabili večji odmerek zdravila Ozempic, kot bi smeli, se takoj posvetujte z zdravnikom.
English: The mean volume of distribution of semaglutide following subcutaneous administration in patients with type 2 diabetes was approximately 12.5 L. Semaglutide was extensively bound to plasma albumin
Slovenian: Povprečni volumen porazdelitve semaglutida po subkutani uporabi pri bolnikih s sladkorno boleznijo tipa 2 je bil približno 12,5 l. Semaglutid je v veliki meri vezan na albumin v plazmi (> 99 %).
English: After your injection
Slovenian: Po injiciranju
English: The postprandial triglyceride and VLDL cholesterol response to a high fat meal was reduced by >40%.
Slovenian: Postprandialni odziv trigliceridov in holesterola VLDL na zelo masten obrok se je zmanjšal za
English: In cardiovascular high risk population the adverse reaction profile was similar to that seen in the other phase 3a trials (described in section 5.1).
Slovenian: 2-letno preskušanje srčno-žilnih izidov in varnosti V populaciji z velikim srčno-žilnim tveganjem so bile značilnosti neželenih učinkov podobne kot v drugih preskušanjih faze 3a (opisani so v poglavju 5.1).
English: No dose adjustment is required for patients with mild, moderate or severe renal impairment.
Slovenian: Pri zdravljenju bolnikov z blago, zmerno ali hudo okvaro ledvic prilagoditev odmerka ni potrebna.
English: When Ozempic is added to existing therapy of sulfonylurea or insulin, a reduction in the dose of sulfonylurea or insulin should be considered to reduce the risk of hypoglycaemia (see sections 4.4 and
Slovenian: Če je zdravilo Ozempic dodano obstoječemu zdravljenju s sulfonilsečnino ali insulinom, je treba razmisliti o zmanjšanju odmerka sulfonilsečnine ali insulina, da bi zmanjšali tveganje za hipoglikemijo (glejte poglavji 4.4 in 4.8).
English: Infants were slightly smaller at delivery, but recovered during the lactation period.
Slovenian: Mladiči so bili ob rojstvu nekoliko manjši,
English: Change from baseline at week 30
Slovenian: Sprememba od izhodišča v 30. tednu
English: Self-monitoring of blood glucose is not needed in order to adjust the dose of Ozempic.
Slovenian: Za prilagoditev odmerka zdravila Ozempic ni potrebna samokontrola glukoze v krvi.
English: In a 30-week double-blind placebo-controlled trial, 388 patients inadequately controlled with diet and exercise, were randomised to Ozempic 0.5 mg or Ozempic 1 mg once weekly or placebo.
Slovenian: V 30-tedenskem, dvojno slepem, s placebom kontroliranem preskušanju so 388 bolnikov, nezadostno urejenih z dieto in telesno vadbo, randomizirali na 0,5 mg ali 1 mg zdravila Ozempic enkrat na teden ali na placebo.
English: A prolonged period of observation and treatment for these symptoms may be necessary, taking into account the long half-life of semaglutide of approximately 1 week (see section 5.2).
Slovenian: Upoštevaje dolg razpolovni čas semaglutida (ki je približno 1 teden) je lahko potrebno podaljšanje obdobja opazovanja in zdravljenja teh simptomov (glejte poglavje 5.2).
English: Hepatic impairment did not have any impact on the exposure of semaglutide.
Slovenian: Okvara jeter ni vplivala na izpostavljenost semaglutidu.
English: • gall stones
Slovenian: • žolčni kamni
English: What Ozempic looks like and contents of the pack Ozempic is a clear and colourless or almost colourless solution for injection in a pre-filled pen.
Slovenian: Zdravilo Ozempic je bistra, brezbarvna ali skoraj brezbarvna raztopina za injiciranje v napolnjenem injekcijskem peresniku.
English: Ozempic is given as an injection under the skin (subcutaneous injection).
Slovenian: Kako se uporablja zdravilo Ozempic Zdravilo Ozempic je namenjeno injiciranju pod kožo (subkutana uporaba).
English: Compared to placebo, semaglutide improved first- and second-phase insulin response with a 3- and 2-fold increase, respectively, and increased maximal beta-cell secretory capacity in patients with type 2 diabetes.
Slovenian: Pri bolnikih s sladkorno boleznijo tipa 2 je semaglutid v primerjavi s placebom izboljšal odziv insulina prve in druge faze s 3-kratnim (prva faza) in 2-kratnim (druga faza) povečanjem ter povečal največjo sekrecijsko sposobnost celic beta.
English: In fertility studies in rats, semaglutide did not affect mating performance or male fertility.
Slovenian: V študijah plodnosti pri podganah semaglutid ni vplival na sposobnost za parjenje ali plodnost podganjih samcev.
English: In female rats, an increase in oestrous cycle length and a small reduction in corpora lutea (ovulations) were observed at doses associated with maternal body weight loss.
Slovenian: Pri podganjih samicah so opažali podaljšanje estrusnega ciklusa in majhno zmanjšanje števila rumenih telesc (ovulacij) ob odmerkih, ki so bili povezani z zmanjšanjem telesne mase samic.
English: Press and hold in the dose button until the dose counter returns to 0.
Slovenian: Pritisnite in držite potisni gumb, dokler se števec odmerka ne vrne na 0.
English: Favours placebo
Slovenian: V korist placeba
English: Semaglutide exposure increased in a dose proportional manner for doses of 0.5 mg and 1 mg.
Slovenian: Izpostavljenost semaglutidu se je ob odmerkih 0,5 mg in 1 mg povečala sorazmerno z odmerkom.
English: Pharmacotherapeutic group: Drugs used in diabetes, Glucagon-like peptide-1 (GLP-1) analogues, ATC code: A10BJ06
Slovenian: Farmakoterapevtska skupina: zdravila za zdravljenje diabetesa, analogi glukagonu podobnega peptida-1 (GLP-1).
English: Sodium content This medicine contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially ‘sodium-free'.
Slovenian: Vsebnost natrija To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na odmerek, kar v bistvu pomeni "brez natrija".
English: Time since randomisation (week) Ozempic 0.5 mg Sitagliptin
Slovenian: sprememba od izhodišča čas od randomizacije (tedni) Ozempic 0,5 mg sitagliptin
English: • When you are not using the pen, keep the pen cap on in order to protect from light.
Slovenian: • Kadar injekcijskega peresnika ne uporabljate, naj bo pokrit s pokrovčkom za zagotovitev zaščite pred svetlobo.
English: However, when initiating treatment with Ozempic in combination with a sulfonylurea or an insulin, blood glucose self-monitoring may become necessary to adjust the dose of the sulfonylurea or the insulin to reduce the risk of hypoglycaemia (see section 4.4).
Slovenian: Vendar bodo bolniki na začetku zdravljenja z zdravilom Ozempic v kombinaciji s sulfonilsečnino ali insulinom morda morali izvajati samokontrolo glukoze v krvi, da bo mogoče prilagoditi odmerek sulfonilsečnine ali insulina z namenom zmanjšanja tveganja za hipoglikemijo (glejte poglavje 4.4).
English: After the first use of the pen, store below 30°C.
Slovenian: Po prvi uporabi shranjujte injekcijski peresnik pri temperaturi do 30 °C.
English: In juvenile rats, semaglutide caused delayed sexual maturation in both males and females.
Slovenian: Pri mladih podganah je semaglutid pri samcih in samicah povzročil zapoznelo spolno dozorevanje.
English: • The other ingredients are: disodium phosphate dihydrate, propylene glycol, phenol, water for injections, sodium hydroxide/hydrochloric acid (for pH adjustment).
Slovenian: • Druge sestavine zdravila so natrijev hidrogenfosfat dihidrat, propilenglikol, fenol, voda za injekcije, natrijev hidroksid (za uravnavanje pH) in klorovodikova kislina (za uravnavanje pH).
English: Nausea occurred in 17.0% and 19.9% of patients when treated with semaglutide 0.5 mg and 1 mg, respectively, diarrhoea in 12.2% and 13.3% and vomiting in 6.4% and 8.4%.
Slovenian: Pri bolnikih, zdravljenih z 0,5 mg oz. 1 mg semaglutida, se je navzea pojavila pri 17,0 % prvih in 19,9 % drugih, driska pri 12,2 % prvih in 13,3 % drugih ter bruhanje pri 6,4 % prvih in 8,4 % drugih.
English: • Take a new needle and tear off the paper tab.
Slovenian: • Vzemite novo injekcijsko iglo in z nje odstranite papirno nalepko.
English: Treatment with semaglutide demonstrated sustained, statistically superior and clinically meaningful reductions in HbA1c and body weight for up to 2 years compared to placebo and active control treatment (sitagliptin, insulin glargine, exenatide ER and dulaglutide).
Slovenian: Zdravljenje s semaglutidom je v primerjavi s placebom in aktivnimi primerjalnimi zdravili (sitagliptinom, insulinom glargin, eksenatidom v obliki s podaljšanim sproščanjem (ER) in dulaglutidom) pokazalo trajno, statistično superiorno in klinično pomembno znižanje HbA1c in telesne mase za obdobje do 2 leti.
English: Figure 2 Mean change in HbA1c (%) and body weight (kg) from baseline to week 40
Slovenian: Povprečna sprememba HbA1c (%) in telesne mase (kg) od izhodišča do 40. tedna
English: Semaglutide did not affect male fertility in rats.
Slovenian: Semaglutid ni vplival na plodnost podganjih samcev.
English: • Your doctor may increase your dose to 1 mg once a week if your blood sugar is not controlled well enough with a dose of 0.5 mg once a week.
Slovenian: • Če krvnega sladkorja z odmerkom 0,5 mg enkrat na teden nimate dovolj dobro urejenega, vam zdravnik lahko odmerek poveča na 1 mg enkrat na teden.
English: When to use Ozempic
Slovenian: Kdaj uporabiti zdravilo Ozempic
English: Non-lethal thyroid C-cell tumours observed in rodents are a class effect for GLP-1 receptor agonists.
Slovenian: Tumorji parafolikularnih celic ščitnice, ki niso bili smrtni in so jih opažali pri glodalcih, so učinek skupine agonistov receptorjev GLP-1.
English: 3 pens and 12 disposable NovoFine Plus needles.
Slovenian: 3 napolnjeni injekcijski peresniki in 12 igel NovoFine Plus za enkratno uporabo.
English: Patients with low body weight may experience more gastrointestinal side effects when treated with semaglutide.
Slovenian: Bolniki z majhno telesno maso imajo lahko med zdravljenjem s semaglutidom več neželenih učinkov na prebavilih.
English: What Ozempic contains
Slovenian: Kaj vsebuje zdravilo Ozempic
English: One ml of solution contains 1.34 mg of semaglutide*.
Slovenian: En ml raztopine vsebuje 1,34 mg semaglutida*.
English: In a 104-week double-blind trial (SUSTAIN 6), 3,297 patients with type 2 diabetes mellitus at high cardiovascular risk were randomised to either Ozempic 0.5 mg once weekly, Ozempic 1 mg once weekly or corresponding placebo in addition to standard-of-care hereafter followed for 2 years.
Slovenian: V 104-tedenskem dvojno slepem preskušanju (SUSTAIN 6) so 3.297 bolnikov s sladkorno boleznijo tipa 2 in velikim srčno-žilnim tveganjem randomizirali (ob optimalnem režimu zdravljenja) na 0,5 mg zdravila Ozempic enkrat na teden, 1 mg zdravila Ozempic enkrat na teden ali ustrezen placebo in jih nato spremljali 2 leti.
English: The incidence of discontinuation of treatment due to adverse events was 6.1% and 8.7% for patients treated with semaglutide 0.5 mg and 1 mg, respectively, versus 1.5% for placebo.
Slovenian: Pojavnost prekinitev zdravljenja zaradi neželenih učinkov je bila med uporabo 0,5 mg semaglutida 6,1 %, med uporabo 1 mg semaglutida 8,7 % in med uporabo placeba 1,5 %.
English: Gastrointestinal disorders were the most frequent adverse events, and occurred in similar proportion of patients receiving Ozempic 0.5 mg (129 patients [43%]), Ozempic 1 mg (133 [44%]), and dulaglutide 1.5 mg (143 [48%]); fewer patients had gastrointestinal disorders with dulaglutide 0.75 mg (100
Slovenian: Najpogostejši neželeni učinki so bili bolezni prebavil, ki so se pojavljali pri primerljivem deležu bolnikov, ki so prejemali zdravilo Ozempic 0,5 mg (129 bolnikov [43 %]), zdravilo Ozempic 1 mg (133 bolnikov [44 %]) in 1,5 mg dulaglutida (143 bolnikov [48 %]).
English: Time from randomisation (week) Ozempic
Slovenian: Čas od randomizacije (tedni)