FrancophonIA/ELRC3.0 huggingface dataset:
English: • if you have liver problems or mild or moderate kidney disease
Slovenian: • če imate težave z jetri ali blago do zmerno ledvično bolezen;
English: • low levels of blood sugar,
Slovenian: • nizke ravni sladkorja v krvi,
English: The granules should not be crushed or chewed, as this impairs the gastro-resistant coating.
Slovenian: Zrnc se ne sme drobiti ali žvečiti, saj se s tem poškoduje gastrorezistentna obloga.
English: Mild to moderate renal impairment
Slovenian: Blaga do zmerna okvara ledvic
English: The recommended dose for adults is 1 sachet three times a day, with a schedule of 1 sachet every 8 hours.
Slovenian: Priporočeni odmerek za odrasle je 1 vrečica trikrat na dan, pri čemer je treba vzeti 1 vrečico na vsakih 8 ur.
English: Pleural or synovial fluid concentrations are approximately equal to plasma.
Slovenian: Koncentracije v plevralni in sinovialni tekočini so približno enake kot v plazmi.
English: During the first 3 months of your treatment with GRANUPAS, you must be attentive to any sign of allergic reaction (for example skin eruption, itchy red spots on the skin, itching, rash, watery or itchy eyes or stuffy nose) or hepatitis (for example fever, fatigue, dark urine, pale stool, abdominal pain, yellow skin and eyes).
Slovenian: V prvih 3 mesecih zdravljenja z zdravilom GRANUPAS morate biti pozorni na kakršne koli znake alergijske reakcije (na primer kožni izpuščaj, srbeče rdeče pike na koži, srbenje, izpuščaj, solzne ali srbeče oči ali zamašen nos) ali hepatitisa (na primer zvišano telesno temperaturo, utrujenost, temen urin, svetlo blato, bolečine v trebuhu, porumenelo kožo in oči) .
English: The optimal dose regimen in children is uncertain.
Slovenian: Optimalna shema odmerjanja pri otrocih ni določena.
English: The medicinal product should be swallowed immediately after mixing with orange juice, tomato juice, apple sauce and yogurt whilst the granules are intact.
Slovenian: Zdravilo je treba zaužiti takoj, ko se zmeša s pomarančnim sokom, paradižnikovim sokom, jabolčno čežano ali jogurtom, pri čemer zrnca ostanejo nespremenjena.
English: For infants, children and adolescents the dosage will be adapted to the patient's weight at 150 mg/kg per day, divided in two intakes.
Slovenian: Odmerek za dojenčke, otroke in mladostnike se bo določil glede na bolnikovo telesno maso, tako da bo ustrezal odmerku 150 mg/kg na dan, ki bo razdeljen v dva odmerka.
English: The lack of a dose-response relationship suggests that the findings are not of clinical relevance, but it is noted that the findings were observed at doses below those proposed clinically.
Slovenian: Zaradi odsotnosti povezave med odmerkom in odzivom je mogoče sklepati, da ugotovitve niso klinično pomembne, vendar pa je treba izpostaviti, da so ugotovitve temeljile na odmerkih, ki so bili manjši od klinično priporočenih.
English: Pharmacotherapeutic group: Antimycobacterials, drugs for treatment of tuberculosis, ATC code: J04AA01
Slovenian: Farmakoterapevtska skupina: učinkovine za zdravljenje infekcij z mikobakterijami, zdravila z delovanjem na Mycobacterium tuberculosis, oznaka ATC: J04AA01
English: Lucane Pharma 172 rue de Charonne 75011 Paris France
Slovenian: Lucane Pharma, 172 rue de Charonne 75011 Pariz
English: (*) in subjects also infected with HIV thyroid gland problems and specifically underactive thyroid or low levels of thyroid hormones, are a very common side effect that may affect more than 1 in 10 people.
Slovenian: (*) pri bolnikih, ki so sočasno okuženi z virusom HIV, so motnje v delovanju ščitnice, posebej zmanjšano delovanje ščitnice ali nizke ravni ščitničnih hormonov, pogosti stranski učinki, ki lahko prizadenejo več kot 1 od 10 bolnikov.
English: • To measure the dose: o Lines on the spoon indicate the amount (in milligrams of para-aminosalicylic acid).
Slovenian: • Navodila za odmerjanje: o črte na žlički označujejo količino (miligrame para-aminosalicilne kisline).
English: Patients should be advised that the skeletons of the granules may be seen in the stools.
Slovenian: Bolnikom je treba pojasniti, da lahko v blatu opazijo lupinice zrnc.
English: The plasma half-life of this agent is about 1 hour, the concentration is not substantially altered in hepatic dysfunction.
Slovenian: Plazemski razpolovni čas te učinkovine je približno 1 ura, koncentracija pa ni veliko drugačna pri okvarjenem delovanju jeter.
English: Because the granules are protected by an enteric coating, absorption does not commence until they leave the stomach.
Slovenian: Ker zrnca ščiti enterična obloga, se absorpcija začne šele, ko zrnca preidejo skozi želodec.
English: GRANUPAS is not recommended during pregnancy and should only be used if advised by your physician.
Slovenian: Zdravilo GRANUPAS med nosečnostjo ni priporočljivo in ga lahko uporabljate samo, če vam je tako svetoval zdravnik.
English: *see Description of selected adverse reactions below Description of selected adverse reactions
Slovenian: *Glejte Opis izbranih neželenih učinkov spodaj.
English: The drug does not cross the blood brain barrier in patients unless the meninges are inflamed, when the concentration of para-aminosalicylic acid in cerebrospinal fluid is about 10 to 50% of the plasma.
Slovenian: Zdravilo pri bolnikih ne prehaja skozi krvno-možgansko pregrado, razen v primeru vnetja možganskih ovojnic, ko koncentracija para-aminosalicilne kisline v cerebrospinalni tekočini znaša približno 10 do 50 % plazemske.
English: Smaller doses in children should be measured using the dosing spoon and given by sprinkling on apple sauce or yogurt.
Slovenian: Manjše odmerke za otroke je treba odmeriti z merilno žličko in jih stresti v jabolčno čežano ali jogurt.
English: The first symptoms usually appear within three months of the start of therapy with a rash as the most common adverse reaction followed by fever and much less frequently by gastrointestinal disturbances of anorexia, nausea or diarrhoea.
Slovenian: Prvi simptomi se običajno pojavijo v treh mesecih od začetka zdravljenja, pri čemer se najpogosteje pojavi izpuščaj, ki mu sledijo zvišana telesna temperatura in precej manj pogosto prebavne motnje, kot so anoreksija, navzea ali driska.
English: In the table below all adverse reactions are listed by system organ class and by frequency.
Slovenian: V spodnji preglednici so navedeni vsi neželeni učinki glede na organski sistem in pogostnost.
English: The dosage is doubled every 2 days until reaching a total of 1 gram after which the dosage is divided to follow the regular schedule of administration.
Slovenian: Nato je treba odmerek vsaka dva dni podvojiti, dokler skupni odmerek ne znaša 1 g; potem je treba odmerek razdeliti tako, da se nadaljuje z dajanjem zdravila po običajni shemi odmerjanja.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Slovenian: Druga zdravila in zdravilo GRANUPAS Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo.
English: The mechanism of action of para-aminosalicylic acid resembles the sulfonamides, competing with paraminobenzoic acid (PABA) for dihydropteroate synthetase (DHP), a key enzyme in the biosynthesis of folates.
Slovenian: Mehanizem delovanja para-aminosalicilne kisline je podoben kot pri sulfonamidih, ki tekmujejo s para-aminobenzojsko kislino (PABA) za vezavo na dihidropteroat sintetazo (DHP), ki je ključni encim za biosintezo folatov.
English: Cutaneous hypersensitivity reactions were also frequent as well as adverse reactions related to the nervous system.
Slovenian: Pogoste so bile tudi preobčutljivostne kožne reakcije in neželeni učinki, povezani z živčevjem.
English: Severe renal disease.
Slovenian: Huda ledvična bolezen.
English: Given that the metabolites of para-aminosalicylic acid are largely excreted via glomerular filtration, caution is warranted in patients with mild to moderate renal impairment (see also section 4.3).
Slovenian: Zaradi dejstva, da se presnovki para-aminosalicilne kisline pretežno izločajo z glomerulno filtracijo, je potrebna previdnost pri bolnikih z blago do zmerno okvaro ledvic (glejte tudi poglavje 4.3).
English: • Make your child eat it straight away.
Slovenian: • Otrok naj mešanico takoj zaužije.
English: Lucane Pharma
Slovenian: Lucane Pharma Teл.
English: In human lymphocyte cultures in-vitro clastogenic effects of achromatic, chromatid, isochromatic breaks or chromatid translocations were not seen at 153 or 600 µg /mL but at 1500 and 3000 µg /mL there was a dose related increase in chromatid aberrations.
Slovenian: Na kulturah človeških limfocitov in vitro pri 153 in 600 µg/ml niso opazili klastogenih učinkov v smislu akromatskih, kromatidnih in izokromatskih prelomov ali translokacij kromatid, pri 1500 in 3000 µg/ml pa so opazili z odmerkom povezano povečanje števila kromatidnih aberacij.
English: As there are no adequate and well controlled studies of para- aminosalicylic acid in humans, para-aminosalicylic acid should be given to a pregnant woman only if clearly needed.
Slovenian: Ker ni bila izvedena nobena zadovoljiva in dobro kontrolirana študija uporabe para-aminosalicilne kisline pri ljudeh, se lahko para-aminosalicilno kislino uporablja pri nosečnicah samo, če je to nujno potrebno.
English: The cumulative excretion of para-aminosalicylic after 24 hours is 84% of an oral dose of 4 g, 21% as para-aminosalicylic acid and 63% as the acetylated form.
Slovenian: Kumulativno izločanje para-aminosalicilne kisline po 24 urah znaša 84 % 4-gramskega peroralnega odmerka, od tega se 21 % izloči v obliki para-aminosalicilne kisline, 63 % pa v acetilirani obliki.
English: • elevated liver enzymes,
Slovenian: • zvišani jetrni encimi,
English: Para-aminosalicylic acid may cause hepatitis.
Slovenian: Para-aminosalicilna kislina lahko povzroči hepatitis.
English: A calibrated measuring spoon is provided.
Slovenian: Priložena je umerjena merilna žlička.
English: The contents of the sachet should be added to a glass of orange or tomato juice.
Slovenian: Vsebino vrečice je treba stresti v kozarec pomarančnega ali paradižnikovega soka.
English: Swallow the granules whole.
Slovenian: Zrnca zaužijte cela.
English: It is unknown whether it passes through the placental barrier.
Slovenian: Ni znano, ali zdravilo prehaja skozi placento.
English: It is important that you do not dissolve, crush or chew the granules as they may not absorb properly and may cause stomach ache or bleeding.
Slovenian: drobite ali žvečite, saj se morda ne bodo pravilno absorbirala in bodo lahko povzročila bolečine ali krvavitev v želodcu.
English: It inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Slovenian: Kislina zavira razvoj odpornosti bakterije proti streptomicinu in izoniazidu.
English: • reduction of the ability of red blood cells to release oxygen
Slovenian: • zmanjšana zmogljivost rdečih krvnih celic za sproščanje kisika,
English: Uncommon side effects (may affect more than 1 in 1,000 people): • loss of appetite (anorexia).
Slovenian: Občasni neželeni učinki (lahko se pojavijo pri več kot 1 od 1.000 bolnikov): • izguba teka (neješčnost).
English: Results indicate that para-aminosalicylic acid was considered not to have produced any clastogenic effect in mice treated at non-toxic dose levels (examined 24 hours after 2 daily administrations of 312.5 to 1250 mg/kg).
Slovenian: Rezultati in vivo študije genotoksičnosti (mikronukleusni preiskus) para-aminosalicilne kisline niso potrdili nobenih klastogenih učinkov para-aminosalicilne kisline na miši, ki so prejele netoksične odmerke (proučevano 24 ur po 2 dnevnih vnosih po 312,5 do 1250 mg/kg).
English: Do not use this medicine after the expiry date which is stated on the carton and sachet after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in vrečici poleg oznake „uporabno do“.
English: The small granules are designed to escape the restriction on gastric emptying of large particles.
Slovenian: Majhna zrnca so zasnovana tako, da se je mogoče izogniti omejitvam, povezanim s prehajanjem velikih delcev skozi želodec.
English: • if you have a stomach ulcer
Slovenian: • če imate razjedo želodca;
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON BOX
Slovenian: PODATKI NA ZUNANJI OVOJNINI KARTONASTA ŠKATLA
English: Hypothyroidism in HIV co-infected patients
Slovenian: Hipotiroidizem pri bolnikih, ki so sočasno okuženi z virusom HIV
English: Small amounts of this agent are distributed in the milk and bile.
Slovenian: Majhne količine te učinkovine se porazdelijo po mleku in žolču.
English: GRANUPAS should not be used during breast-feeding.
Slovenian: Zdravila GRANUPAS se med dojenjem ne sme uporabljati.
English: Literature reports on para- aminosalicylic acid in pregnant women always report co-administration of other medicinal products.
Slovenian: Poročila iz literature v zvezi z uporabo para-aminosalicilne kisline pri nosečnicah vedno navajajo sočasno uporabo drugih zdravil.
English: In the rabbit, sodium aminosalicylate had no effects on embryofoetal development; however, the doses evaluated were below those proposed clinically.
Slovenian: Pri kuncih natrijev aminosalicilat ni vplival na embriofetalni razvoj, vendar pa so bili proučevani odmerki manjši od klinično priporočenih.
English: No drug interaction studies have been conducted in patients with HIV infection taking antiretroviral agents and para-aminosalicylic acid.
Slovenian: Študij medsebojnega delovanja zdravil na bolnikih, okuženih z virusom HIV, ki jemljejo protiretrovirusna zdravila in para-aminosalicilno kislino, niso izvedli.
English: The concentration of the metabolite may be increased in cases of renal failure.
Slovenian: Koncentracija presnovka je lahko večja v primeru ledvične odpovedi.
English: GRANUPAS is not recommended during pregnancy and in women of childbearing potential not using contraception.
Slovenian: Zdravila GRANUPAS ne uporabljajte pri nosečnicah in pri ženskah v rodni dobi, ki ne uporabljajo učinkovite kontracepcije.
English: Gastro-resistant granules The granules are small off white/ light brown coloured approximately 1.5 mm diameter.
Slovenian: Zrnca so majhna, umazano bele/svetlorjave barve in imajo premer približno 1,5 mm.
English: Bone defects were observed at 77 mg/kg only.and increased foetal weight was noted at the other doses.
Slovenian: Samo pri odmerku 77 mg/kg so opazili okvare kosti; pri vseh ostalih odmerkih so zabeležili zvečanje telesne mase ploda.
English: Patients with severe renal impairment should not receive para-aminosalicylic acid.
Slovenian: Bolniki s hudo okvaro ledvic ne smejo uporabljati para-aminosalicilne kisline.
English: They will not dissolve, but swirling the juice in the glass will help re-suspend the granules if they sink.
Slovenian: Zrnca se ne bodo raztopila, vendar jih lahko, če se usedejo na dno, z mešanjem soka v kozarcu ponovno umešamo v raztopino.
English: If you take more GRANUPAS than you should
Slovenian: Če ste vzeli večji odmerek zdravila GRANUPAS, kot bi smeli
English: The major metabolites of PAS are produced by conjugation to glycine in para-aminosalicyluric acid (PASU) for up to 25% of the dose and to N-acetyl in N-acetyl para-aminosalicylic acid (Ac-PAS) for up to 70% of the dose.
Slovenian: Glavna presnovka para-aminosalicilne kisline nastaneta s konjugacijo: z glicinom v para aminosalicilurno kislino (PASU) (do 25 % odmerka) in z N-acetilom v N-acetil-para-aminosalicilno kislino (Ac-PAS) (do 70 % odmerka).
English: Para-aminosalicylic acid is distributed in various tissues and fluids including the lungs, kidneys, liver and peritoneal fluid.
Slovenian: Para-aminosalicilna kislina se porazdeli po različnih tkivih in tekočinah, vključno s pljuči, ledvicami, jetri in peritonealno tekočino.
English: • Sprinkle the granules onto apple sauce or yogurt.
Slovenian: • Stresite zrnca v jabolčno čežano ali jogurt.
English: Para-aminosalicylic acid may decrease the gastrointestinal absorption of digoxin, by inhibiting the absorption function of intestinal cells.
Slovenian: Para-aminosalicilna kislina lahko zmanjša absorpcijo digoksina v prebavilih, saj zavira absorpcijsko delovanje črevesnih celic.
English: GRANUPAS is a gastro-resistant preparation and, therefore, the acid-resistant coating of the granules protects against degradation in the stomach therefore preventing the formation of meta-aminophenol (a known hepatotoxin).
Slovenian: Zdravilo GRANUPAS je gastrorezistenten pripravek, kar pomeni, da obloga, odporna proti kislinam, ščiti zrnca pred razgradnjo v želodcu in tako preprečuje, da bi se tvoril meta-aminofenol (znan hepatotoksin).
English: In a single dose study the plasma half-life of para-aminosalicylic acid administered as GRANUPAS was 1.62 ± 0.85 h.
Slovenian: Izločanje V študiji enkratnega odmerka je bil plazemski razpolovni čas para-aminosalicilne kisline po dajanju zdravila GRANUPAS 1,62 ± 0,85 ure.
English: Treatment is usually given for two years (24 months).
Slovenian: Ne vzemite več kot 3 vrečice na dan. Zdravljenje običajno traja dve leti (24 mesecev).
English: GRANUPAS contains para-aminosalicylic acid which is used in adults and children aged 28 days and older to treat resistant tuberculosis in combination with other medicines, in cases of resistance or intolerability with other treatments.
Slovenian: Zdravilo GRANUPAS vsebuje para-aminosalicilno kislino, ki se uporablja v kombinaciji z drugimi zdravili za zdravljenje odporne tuberkuloze pri odraslih in otrocih, starih 28 dni ali več, v primeru odpornosti ali neprenašanja drugih zdravil.
English: • Do not use the sachet if it is swollen or the granules have lost their light brown colour.
Slovenian: • Ne uporabite vrečice, če je nabrekla ali če so zrnca izgubila svetlorjavo barvo.
English: Speak to a doctor or pharmacist.
Slovenian: Posvetujte se z zdravnikom ali farmacevtom.
English: Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis.
Slovenian: Mehanizem delovanja Aminosalicilna kislina je bakteriostatik, ki deluje proti bakteriji Mycobacterium tuberculosis.
English: • Obligation to conduct post-authorisation measures
Slovenian: • Obveznost izvedbe ukrepov po pridobitvi dovoljenja za promet Jih ni.
English: • Use the spoon that comes with the medicine to measure the dose.
Slovenian: • Za odmerjanje uporabite žličko, ki je priložena zdravilu.
English: GRANUPAS is indicated for use as part of an appropriate combination regimen for multi-drug resistant tuberculosis in adults and paediatric patients from 28 days of age and older when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.
Slovenian: Zdravilo GRANUPAS je indicirano za uporabo v kombinaciji z drugimi ustreznimi zdravili za zdravljenje tuberkuloze, odporne proti več zdravilom, pri odraslih in pediatričnih bolnikih, starih 28 dni ali več, kadar zaradi odpornosti ali neprenašanja ni mogoče sestaviti druge učinkovite kombinacije zdravil.
English: Very rare Thrombocytopenia, purpura, leukopenia, anemia, methemoglobinemia, agranulocytosis.
Slovenian: Bolezni krvi in limfatičnega sistema zelo redki trombocitopenija, purpura, levkopenija, anemija, methemoglobinemija, agranulocitoza
English: The sachets can be stored below 25°C up to 24 hours after first opening.
Slovenian: Vrečice lahko po prvem odprtju shranjujete največ 24 ur pri temperaturi do 25 °C.
English: The complete syndrome includes steatorrhoea, an abnormal small bowel pattern on x-ray, villus atrophy, depressed cholesterol, reduced D-xylose and iron absorption.
Slovenian: Popoln sindrom vključuje steatorejo, spremembe vijug tankega črevesa, vidne na rentgenskem posnetku, atrofijo črevesnih resic, prenizek holesterol ter zmanjšano absorpcijo D-ksiloze in železa.
English: Para-aminosalicylic acid is acetylated in the liver and converted into the inactive metabolite, N-acetylpara-aminosalicylic acid which is devoid of bacteriostatic activity.
Slovenian: Para-aminosalicilna kislina se acetilira v jetrih in se pretvori v neaktivni presnovek, N-acetil-para aminosalicilno kislino, ki nima bakteriostatičnega učinka.
English: Desensitization can be accomplished by starting with 10 mg para-aminosalicylic acid (PAS) given as a single dose.
Slovenian: Desenzibilizacijo je mogoče doseči tako, da se na začetku zdravljenja daje 10 mg para-aminosalicilne kisline (PAS) v enkratnem odmerku.
English: What you need to know before you take GRANUPAS Do not take GRANUPAS
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo GRANUPAS Ne jemljite zdravila GRANUPAS:
English: Do not breastfeed whilst taking GRANUPAS.
Slovenian: Med jemanjem zdravila GRANUPAS ne smete dojiti.
English: This medicinal product decreases the gastrointestinal absorption of para-aminosalicylic acid, and should not be administered concomitantly.
Slovenian: To zdravilo zmanjša absorpcijo para-aminosalicilne kisline v prebavilih, zato se ga ne sme uporabljati sočasno z njo.
English: Antiretrovirals
Slovenian: Protiretrovirusna zdravila
English: The sachets can be stored below 25°C up to 24 hours after opening.
Slovenian: Vrečice lahko po odprtju shranjujete največ 24 ur pri temperaturi do 25 °C.
English: A malabsorption syndrome can develop in patients on para-aminosalicylic acid, but is usually not complete.
Slovenian: Pri bolnikih, ki se zdravijo s para-aminosalicilno kislino, se lahko razvije malabsorpcijski sindrom, ki pa se običajno ne kaže z vsemi značilnimi znaki.
English: • reduction in numbers of white blood cells,
Slovenian: • zmanjšanje števila belih krvnih celic,
English: • Do not crush or chew the granules.
Slovenian: • Zrnc ne smete drobiti ali žvečiti.
English: Given the metabolic pathway of para-aminosalicylic acid no significant drug interaction is anticipated.
Slovenian: Glede na presnovno pot para aminosalicilne kisline pomembnejšega medsebojnega delovanja zdravil ni pričakovati.
English: Sachets consisting of paper/low density polyethylene/aluminium foil/primer/low density polyethylene.
Slovenian: Vrečice iz papirja/polietilena nizke gostote/aluminijaste folije/prevleke/polietilena nizke gostote.
English: Do not use this medicine if you notice the sachets are swollen or if the granules are dark brown or purple.
Slovenian: Ne uporabljajte tega zdravila, če opazite, da so vrečice nabrekle ali da so zrnca temnorjava ali škrlatno rdeča.
English: The other ingredients are silica, colloidal hydrated, dibutyl sebacate, methacrylic acid - ethyl acrylate copolymer (1:1) dispersion 30 per cent, hypromellose, cellulose, microcrystalline, talc.
Slovenian: Druge sestavine zdravila so koloidni hidratirani silicijev dioksid, dibutilsebakat, metakrilna kislina in etilakrilat (kopolimer 1 : 1, 30-odstotna disperzija), hipromeloza, mikrokristalna celuloza in smukec.
English: Co-administration of para- aminosalicylic acid and ethionamide may intensify adverse reactions of para-aminosalicylic acid, mainly the gastrointestinal effects, including jaundice, hepatitis, nausea, vomiting, diarrhoea, abdominal pain or anorexia.
Slovenian: Sočasna uporaba para-aminosalicilne kisline in etionamida lahko okrepi neželene učinke paraaminosalicilne kisline, še zlasti gastrointestinalne neželene učinke, kot so zlatenica, hepatitis, navzea, bruhanje, driska, bolečine v trebuhu ali anoreksija.
English: Para-aminosalicylic acid and its metabolites are excreted by glomerular filtration and tubular secretion.
Slovenian: Para-aminosalicilna kislina in njeni presnovki se izločajo z glomerulno filtracijo in tubulno sekrecijo.
English: How to take GRANUPAS
Slovenian: Kako jemati zdravilo GRANUPAS
English: Sodium aminosalicylic acid was not mutagenic in Ames test strain TA 100.
Slovenian: Natrijeva aminosalicilna kislina se pri Amesovem testu s sevom TA 100 ni izkazala za mutageno.
English: Para-aminosalicylic acid may be associated with an increased risk of hypothyroidism in HIV coinfected patients.
Slovenian: Para-aminosalicilno kislino povezujemo s povečanim tveganjem za pojav hipotiroidizma pri bolnikih, ki so sočasno okuženi z virusom HIV.
English: Very rare side effects (may affect less than 1 in 10,000 people):
Slovenian: Zelo redki neželeni učinki (lahko se pojavijo pri manj kot 1 od 10.000 bolnikov):