FrancophonIA/ELRC3.0 huggingface dataset:
English: The absolute bioavailability of emtricitabine from Emtriva 200 mg hard capsules was estimated to be 93% and the absolute bioavailability from Emtriva 10 mg/mL oral solution was estimated to be 75%.
Maltese: Ir-rata tal-biodisponibiltà assoluta ta' emtricitabine mill-kapsuli iebsin Emtriva ta' 200 mg ġiet stmata li hi ta' 93%, u r-rata tal-biodisponibiltà assoluta mis-soluzzjoni orali Emtriva ta' 10 mg/mL kienet stmata li hi ta' 75%.
English: insomnia, abnormal dreams Nervous system disorders: Very common:
Maltese: nuqqas ta' rqad, ħolm anormali Disturbi fis-sistema nervuża:
English: Creatinine clearance (mL/min)
Maltese: Tneħħija tal-krejatinina (mL/min)
English: Emtriva contains the active substance emtricitabine.
Maltese: Emtriva fiha s-sustanza attiva, emtricitabine.
English: Emtricitabine is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which competitively inhibits HIV-1 reverse transcriptase, resulting in DNA chain termination.
Maltese: Emtricitabine huwa fosforilat permezz ta' enzimi ċellulari biex jifforma emtricitabine 5'-trifosfat li tinibixxi kompetittivament ir-reverse transcriptase ta' l-HIV-1 li jirriżulta fit-terminazzjoni tal-katina tad-DNA.
English: Table 2: Tabulated summary of adverse reactions associated with emtricitabine based on clinical study and post-marketing experience
Maltese: Tabella 2: Sommarju tabulat ta' reazzjonijiet avversi assoċjati ma' emtricitabine bbażat fuq studju kliniku u esperjenza ta' wara t-tqegħid fis-suq
English: Printing ink containing Black iron oxide (E172) Shellac (E904)
Maltese: Linka ta' l-istampar fiha: black iron oxide (E172), shellac (E904)
English: Pharmacokinetic parameters were determined following administration of a single dose of 200 mg emtricitabine hard capsules to 30 non-HIV infected subjects with varying degrees of renal insufficiency.
Maltese: Il-parametri farmakokinetiċi kienu stabbiliti wara li ngħatat doża waħda ta' kapsuli iebsa ta' 200 mg ta' emtricitabine lil 30 individwu mhux infettati bl-HIV, b'livelli varji ta' insuffiċjenza renali.
English: In 20 HIV infected subjects receiving 200 mg emtricitabine daily as hard capsules, steady-state plasma emtricitabine peak concentrations (Cmax), trough concentrations (Cmin) and area under the plasma concentration time curve over a 24-hour dosing interval (AUC) were 1.8 ± 0.7 µg/mL, 0.09 ± 0.07 µg/mL and 10.0 ± 3.1 µg·h/mL, respectively.
Maltese: F'20 individwu infettati bl-HIV li kienu qegħdin jieħdu 200 mg ta' emtricitabine kuljum f'kapsuli iebsin, l-ogħla konċentrazzjonijiet ta' emtricitabine fil-plażma fissa (Cmax), konċentrazzjonijiet l-iżjed baxxi (Cmin), u l-erja taħt il-kurva tal-ħin tal-konċentrazzjonijiet tal-plażma matul interval ta' dożaġġ ta' 24 siegħa (AUC) kienu ta' 1.8 ± 0.7 µg/mL, 0.09 ± 0.07 µg/mL u 10.0 ± 3.1 µg·h/mL, rispettivament.
English: Antiviral activity in vitro: The 50% inhibitory concentration (IC50) value for emtricitabine against laboratory and clinical isolates of HIV-1 was in the range of 0.0013 to 0.5 µmol/l.
Maltese: Il-valur tal-konċentrazzjoni inibitorja ta' 50% (IC50) ta' emtricitabine kontra isolates tal-laboratorju u kliniċi ta' l-HIV-1 kienet fil-medda ta' 0.0013 sa 0.5 µmol/l.
English: Emtriva 200 mg hard capsules are available for adults, adolescents and children who weigh at least 33 kg and can swallow hard capsules.
Maltese: Kapsuli iebsin ta' Emtriva ta' 200 mg huma disponibbli għall-adulti, adolexxenti u tfal li jiżnu millinqas 33 kg u li jistgħu jibilgħu kapsuli iebsin.
English: Subjects were grouped according to baseline creatinine clearance (> 80 mL/min as normal function; 50-80 mL/min as mild impairment; 30-49 mL/min as moderate impairment; < 30 mL/min as severe impairment; < 15 mL/min as functionally anephric requiring haemodialysis).
Maltese: Lindividwi tqassmu skond il-linja bażi tat-tneħħija tal-krejatinina (> 80 mL/min bħala funzjoni normali; 50-80 mL/min bħala indeboliment ħafif; 30-49 mL/min bħala indeboliment moderat; < 30 mL/min bħala indeboliment sever; < 15-il mL/min bħala funzjonament anefriku li jeħtieġ id-dijaliżi taddemm).
English: Intracellular pharmacokinetics: In a clinical study, the intracellular half-life of emtricitabine-triphosphate in PBMCs was 39 hours.
Maltese: Fi studju kliniku, il-half-life intraċellulari ta' emtricitabine-trifosfat f'PBMCs kienet ta' 39 siegħa.
English: Steady-state trough plasma concentrations reached levels approximately 4-fold above the in vitro IC90 values for anti-HIV activity.
Maltese: L-inqas livelli ta' konċentrazzjonijiet tal-plażma fissa laħqu livelli bejn wieħed u ieħor erba' darbiet ogħla mill-valuri IC90 in vitro għall-attività anti-HIV.
English: Paediatric population: The recommended dose of Emtriva 10 mg/mL oral solution is 6 mg/kg up to a maximum of 240 mg (24 mL) once daily.
Maltese: Id-doża rakkomandata ta' Emtriva 10 mg/mL soluzzjoni orali hija ta' 6 mg/kg sa massimu ta' 240 mg (24 mL) darba kuljum.
English: There are no clinically significant interactions when emtricitabine is co-administered with indinavir, zidovudine, stavudine, famciclovir or tenofovir disoproxil fumarate.
Maltese: M'hemmx interazzjonijiet kliniċi sinifikanti meta emtricitabine jingħata flimkien ma' indinavir, zidovudine, stavudine, famciclovir, jew tenofovir disoproxil fumarate.
English: Assessment of adverse reactions from clinical study data is based on experience in three studies in adults (n = 1,479) and three paediatric studies (n = 169).
Maltese: L-istima ta' reazzjonijiet avversi minn dejta ta' studji kliniċi hija bbażata fuq esperjenza minn tliet studji fl-adulti (n = 1,479) u tliet studji pedjatriċi (n = 169).
English: Date of first authorisation: 24 October 2003 Date of latest renewal: 22 September 2008
Maltese: Data tal-aħħar tiġdid: 22 ta' Settembru 2008
English: Mitochondrial dysfunction following exposure in utero Nucleos(t)ide analogues may impact mitochondrial function to a variable degree, which is most pronounced with stavudine, didanosine and zidovudine.
Maltese: Disfunzjoni tal-mitokondrija wara esponiment in utero Analogi tan-nukleos(t)idi jista' jkollhom impatt fuq il-funzjoni tal-mitokondrija sa grad varjabbli, li hu l-aktar notevoli bi stavudine, didanosine u zidovudine.
English: In vitro binding of emtricitabine to human plasma proteins was < 4% and independent of concentration over the range of 0.02-200 µg/mL.
Maltese: It-twaħħil in vitro ta' emtricitabine ma' proteini tal-plażma umana kienet ta' < 4% u indipendenti millkonċentrazzjoni fil-medda ta' 0.
English: hypertriglyceridaemia, hyperglycaemia
Maltese: ipertrigliċeridimija, ipergliċemija
English: Gilead Sciences Slovakia s.r.o.
Maltese: Slovenská republika Gilead Sciences Slovakia, s.r.o.
English: Emtricitabine did not inhibit the enzyme responsible for glucuronidation.
Maltese: Emtricitabine ma impedixxix l-enzima responsabbli għallglukoronidazzjoni.
English: At 48 weeks of treatment the emtricitabine-containing regimen demonstrated an equivalent proportion of patients with HIV RNA < 400 copies/mL (94% emtricitabine versus 92%) and a greater proportion of patients with HIV RNA < 50 copies/mL (95% emtricitabine versus 87%) compared with the patients continuing with their PI-HAART regimen.
Maltese: Wara 48 ġimgħa ta' trattament il-kors li kien fih emtricitabine wera proporzjon ekwivalenti ta' pazjenti bl-RNA tal-HIV b' < 400 kopja/mL (94% emtricitabine kontra 92%) u proporzjon akbar ta' pazjenti bl-RNA tal-HIV b' < 50 kopja/mL (95% emtricitabine kontra 87%) meta mqabbel mal-pazjenti li komplew il-kors PIHAART tagħhom.
English: In general, the pharmacokinetics of emtricitabine in infants, children and adolescents (aged 4 months up to 18 years) are similar to those seen in adults.
Maltese: B'mod ġenerali, il-farmakokinetika ta' emtricitabine fit-trabi, tfal u adolexxenti (età ta' bejn 4 xhur sa 18-il sena) hija simili għal dik osservata fl-adulti.
English: Mechanism of action and pharmacodynamic effects Emtricitabine is a synthetic nucleoside analogue of cytidine with activity that is specific to HIV-1, HIV-2and HBV.
Maltese: Mekkaniżmu ta' azzjoni u effetti farmakodinamiċi Emtricitabine huwa analogu tan-nukleosidi ta' cytidine sintetika b'attività li hija speċifika għallHIV-1, l-HIV-2 u l-HBV.
English: The apparent volume of distribution after intravenous administration of emtricitabine was 1.4 ± 0.3 L/kg, indicating that emtricitabine is widely distributed throughout the body to both intracellular and extracellular fluid spaces.
Maltese: Il-volum apparenti ta' distribuzzjoni wara għoti ġol-vini ta' emtricitabine kien ta' 1.4 ± 0.3 L/kg, li jindika li emtricitabine tinfirex mal-ġisem kollu fl-ispazji fluwidi kemm dawk intraċellurlari u kemm ekstraċellulari.
English: Adults: The recommended dose of Emtriva 10 mg/mL oral solution is 240 mg (24 mL) once daily.
Maltese: Id-doża rakkomandata ta' Emtriva 10 mg/mL soluzzjoni orali hija ta' 240 mg (24 mL) darba kuljum.
English: Methyl parahydroxybenzoate (E218) Propylene glycol
Maltese: Methyl parahydroxybenzoate (E218)
English: Although the mean Cmax and Cmin were approximately 20% higher and mean AUC was 16% higher in females compared to males, this difference was not considered clinically significant.
Maltese: Għalkemm il-medja ta' Cmax u ta' Cmin kienet ta' madwar 20% ogħla u l-medja tal-AUC kienet ta' 16% ogħla fin-nisa meta mqabbla mal-irġiel, din id-differenza ma kinetx ikkunsidrata li kienet klinikament sinifikanti.
English: In the adult studies, 1,039 treatment-naïve and 440 treatment-experienced patients received emtricitabine (n = 814) or comparator medicinal product (n = 665) for 48 weeks in combination with other antiretroviral medicinal products.
Maltese: Fl-istudji fl-adulti, 1,039 pazjent li qatt ma kienu ħadu din it-terapija qabel u 440 pazjent esperjenzati bil-kura, irċivew emtricitabine (n = 814) jew prodott mediċinali biex iqabbel (n = 665) għal 48 ġimgħa flimkien ma' prodotti mediċinali antiretrovirali oħra.
English: Relevant examples include cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jirovecii pneumonia.
Maltese: Eżempji rilevanti jinkludu retinite ċitomegalovirus, infezzjonijiet mikobatterjali ġeneralizzati u/jew fokali, u pulmonite tat-tip Pneumocystis jirovecii.
English: diarrhoea, nausea
Maltese: uġigħ, astenja
English: Elderly patients are more likely to have decreased renal function, therefore caution should be exercised when treating elderly patients with Emtriva (see section 4.2).
Maltese: Pazjenti anzjani huma aktar probabbli li jkollhom tnaqqis tal-funzjoni renali, għalhekk għandha tingħata attenzjoni partikulari meta pazjenti anzjani jkunu qed jingħataw it-trattament b'Emtriva (ara sezzjoni 4.2).
English: Patients with pre-existing liver dysfunction including chronic active hepatitis have an increased frequency of liver function abnormalities during combination antiretroviral therapy (CART) and should be monitored according to standard practice.
Maltese: Pazjenti li diġa jbatu minn disfunzjoni tal-fwied li tinkludi l-epatite kronika attiva, għandhom żdieda fil-frekwenza ta' anormalitajiet tal-funzjoni tal-fwied waqt terapija antiretrovirali kombinata (CART, combination antiretroviral therapy) u jeħtieġ li jiġu monitorjati skond il-prattika normali.
English: Phenotypic analysis showed no significant changes in emtricitabine susceptibility unless the M184V/I mutation had developed.
Maltese: Analiżi fenotipika ma wriet l-ebda tibdil sinifikanti fis-suxxettibiltà għal emtricitabine sakemm ma kinetx żviluppat il-mutazzjoni M184V/1.
English: In addition to the adverse reactions reported in adults, anaemia (9.5%) and skin discolouration (31.8%) occurred more frequently in clinical trials involving HIV infected paediatric patients.
Maltese: Flimkien mar-reazzjonijiet avversi rrappurtati f'pazjenti adulti, anemija (9.5%) u telf tal-kulur tal-ġilda (31.8%) seħħew b'mod iktar frekwenti fi studji kliniċi li kienu jinvolvu pazjenti pedjatriċi infettati bl-HIV.
English: Emtricitabine is principally eliminated by the kidney via glomerular filtration and active tubular secretion.
Maltese: Emtricitabine hija eliminata prinċipalment mill-kliewi permezz ta' filtrazzjoni glomerulari u sekrezzjoni tubulari attiva.
English: In a pilot study in children and a definitive bioequivalence study in adults, the Emtriva 10 mg/mL oral solution was shown to have approximately 80% of the bioavailability of the Emtriva 200 mg hard capsules.
Maltese: Fi studju pilota fit-tfal u fi studju definittiv ta' bijoekwivalenza fl-adulti, is-soluzzjoni orali Emtriva ta' 10 mg/mL ntwera li għandha bejn wieħed u ieħor 80% tar-rata tal-biodisponibiltà tal-kapsuli iebsin Emtriva ta' 200 mg.
English: Capsule contents: microcrystalline cellulose (E460), crospovidone, magnesium stearate (E572), povidone (E1201)
Maltese: Kontenut tal-kapsula: microcrystalline cellulose (E460), crospovidone, magnesium stearate
English: In addition to the adverse reactions reported in adults (see section 4.8, Tabulated summary of adverse reactions), the following adverse reactions were observed more frequently in paediatric patients: anaemia was common (9.5%) and skin discolouration (increased pigmentation) was very common (31.8%) in paediatric patients.
Maltese: Flimkien mar-reazzjonijiet avversi rrappurtati f'pazjenti adulti (ara sezzjoni 4.8, Sommarju tabulat ta' reazzjonijiet avversi), ir-reazzjonijiet avversi li ġejjin kienu osservati b'mod iktar frekwenti f'pazjenti pedjatriċi: anemija kienet komuni (9.5%) u telf tal-kulur tal-ġilda (żieda fil-pigmentazzjoni) kien komuni ħafna (31.8%) f'pazjenti pedjatriċi.
English: Immune system disorders: Common:
Maltese: Disturbi fis-sistema immuni:
English: Emtricitabine did not exhibit cytotoxicity to peripheral blood mononuclear cells (PBMCs), established lymphocyte and monocyte-macrophage cell lines or bone marrow progenitor cells in vitro.
Maltese: Emtricitabine ma jinibixxix ċitotossiċità f'ċelluli mononukleari tad-demm periferali (peripheral blood mononuclear cells, PBMCs), f'razza ta' ċelluli stabbiliti tal-limfoċiti u tal-makrofaġi monoċitiċi jew f'ċelluli progenitriċi tal-mudullun in vitro.
English: Capsule shell: gelatin, indigotine (E132), titanium dioxide (E171) Printing ink containing: black iron oxide (E172), shellac (E904)
Maltese: Qoxra tal-kapsula: gelatin, indigotine (E132), titanium dioxide (E171)
English: Assessment of adverse reactions in paediatric patients from clinical study data is based on experience in three paediatric studies (n = 169) where treatment-naïve (n = 123) and treatment-experienced (n = 46) paediatric HIV infected patients aged 4 months to 18 years were treated with emtricitabine in combination with other antiretroviral agents.
Maltese: L-istima ta' reazzjonijiet avversi f'pazjenti pedjatriċi ta' dejta minn studji kliniċi hija bbażata fuq esperjenza minn tliet studji pedjatriċi (n = 169) fejn pazjenti pedjatriċi infettati bl-HIV li kellhom minn 4 xhur sa 18-il sena, li qatt ma kienu ħadu din it-terapija qabel (n = 123) u dawk esperjenzati bil-kura (n = 46), kienu ttrattati b'emtricitabine flimkien ma' mediċini antiretrovirali oħrajn.
English: Plasma emtricitabine exposure (AUC) in infants up to 3 months of age who received 3 mg/kg emtricitabine once daily was similar to that observed using 6 mg/kg daily doses in HIV infected adults and children aged 4 months and over.
Maltese: L-esponiment ta' emtricitabine fil-plażma (AUC) fi trabi li kellhom sa 3 xhur li rċivew 3 mg/kg ta' emtricitabine darba kuljum kienet simili għal dik li kienet osservata bl-użu ta' dożi ta' 6 mg/kg kuljum f'adulti u tfal infettati bl-HIV li kellhom 4 xhur jew iktar.
English: In virologically stable treatment-experienced adults, emtricitabine, in combination with an NRTI (either stavudine or zidovudine) and a PI or an NNRTI was shown to be non-inferior to lamivudine with respect to the proportion of responders (< 400 copies/mL) through 48 weeks (77% emtricitabine, 82% lamivudine).
Maltese: F'adulti esperjenzati bil-kura, viroloġikament stabbli, emtricitabine kkombinata ma' NRTI (jew stavudine jew zidovudine) u PI jew NNRTI wriet li mhijiex inferjuri għal lamivudine rigward ilproporzjon ta' responders (< 400 kopja/mL) matul 48 ġimgħa (77% emtricitabine, 82% lamivudine).
English: When tested for activity against laboratory strains of HBV, the IC50 value for emtricitabine was in the range of 0.01 to 0.04 µmol/l.
Maltese: Meta ttestajta għall-attività kontra strejns tal-HBV tal-laboratorju, il-valur ta' IC50 għal emtricitabine kien fil-medda ta' 0.01 sa 0.04 µmol/l.
English: Each mL contains 10 mg of emtricitabine.
Maltese: Kull mL fih 10 mg ta' emtricitabine.
English: Table 1: Daily doses of Emtriva 10 mg/mL oral solution adjusted according to creatinine clearance
Maltese: Tabella 1: Dożi ta' kuljum ta' Emtriva 10 mg/mL soluzzjoni orali aġġustati skont it-tneħħija tal krejatinina
English: In virologically stable treatment-experienced adults, emtricitabine, in combination with an NRTI (either stavudine or zidovudine) and a protease inhibitor (PI) or an NNRTI was shown to be non-inferior to lamivudine with respect to the proportion of responders (< 400 copies/mL) through 48 weeks (77% emtricitabine, 82% lamivudine).
Maltese: F'adulti esperjenzati bil-kura, viroloġikament stabbli, emtricitabine kkombinata ma' NRTI (jew stavudine jew zidovudine) u impeditur tal-protease (PI) jew NNRTI wriet li mhijiex inferjuri għal lamivudine rigward il-proporzjon ta' responders (< 400 kopja/mL) matul 48 ġimgħa (77% emtricitabine, 82% lamivudine).
English: Emtriva 200 mg hard capsules
Maltese: Emtriva 200 mg kapsuli iebsin
English: Emtricitabine is primarily excreted via glomerular filtration and active tubular secretion.
Maltese: Emtricitabine jitneħħa mill-ġisem, primarjament, permezz ta' filtrazzjoni glomerulari u sekrezzjoni tubulari attiva.
English: Renal insufficiency: Emtricitabine is eliminated by renal excretion and exposure to emtricitabine was significantly increased in patients with renal insufficiency (see section 5.2).
Maltese: Insuffiċjenza renali: Emtricitabine hija eliminata permezz ta' tneħħija renali u l-esponiment għal emtricitabine jiżdied b'mod sinifikanti f'pazjenti b'insuffiċjenza renali (ara sezzjoni 5.2).
English: elevated serum aspartate aminotransferase (AST) and/or elevated serum ALT, hyperbilirubinaemia Skin and subcutaneous tissue disorders: Common:
Maltese: aspartate aminotransferase (AST) għoli fis-serum u/jew ALT għoli fis-serum, iperbilirubinimja Disturbi fil-ġilda u fit-tessuti ta' taħt il-ġilda:
English: Emtriva oral solution contains sunset yellow (E110) which may cause allergic reactions, methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) which may cause allergic reactions (possibly delayed).
Maltese: Emtriva soluzzjoni orali fiha sunset yellow (E110) li jista' jikkawża reazzjonijiet allerġiċi, methyl parahydroxybenzoate (E218) u propyl parahydroxybenzoate (E216) li jista' jikkawża reazzjonijiet allerġiċi (li jistgħu jittardjaw).
English: Emtriva 200 mg hard capsules Emtricitabine
Maltese: Emtriva 200 mg kapsuli iebsin Emtricitabine
English: Package leaflet: Information for the user Emtriva 10 mg/mL oral solution
Maltese: Informazzjoni għall utent Emtriva 10 mg/mL soluzzjoni orali
English: 2 Anaemia was common and skin discolouration (increased pigmentation) was very common when emtricitabine was administered to paediatric patients (see section 4.8, Paediatric population).
Maltese: 2 Anemija kienet komuni u t-telf tal-kulur tal-ġilda (żieda fil-pigmentazzjoni) kienet komuni ħafna meta emtricitabine ngħata lil pazjenti pedjatriċi (ara sezzjoni 4.8, Popolazzjoni pedjatrika).
English: However, based on the minimal metabolism of emtricitabine and the renal route of elimination it is unlikely that a dose adjustment would be required in patients with hepatic insufficiency (see section 5.2).
Maltese: Madankollu, ibbażat fuq ilmetaboliżmu minimu ta' emtricitabine u r-rotta ta' l-eliminazzjoni renali, huwa improbabbli li jkun meħtieġ aġġustament tad-doża f'pazjenti b'insuffiċjenza epatika (ara sezzjoni 5.2).
English: The bottle contains 170 mL of solution.
Maltese: GĦAMLA FARMAĊEWTIKA U KONTENUT 170 mL soluzzjoni orali.
English: In an open-label, non-comparative study, pharmacokinetic data were obtained from 20 neonates of HIV infected mothers who received two 4-day courses of emtricitabine oral solution between the first week of life and 3 months of age at a dose level of 3 mg/kg once daily.
Maltese: Fi studju open-label, mhux komparattiv, tagħrif farmakokinetiku nkiseb minn 20 tarbija tat-twelid ta' ommijiet infettati bl-HIV li rċivew żewġ korsijiet ta' 4 ijiem ta' soluzzjoni orali emtricitabine bejn lewwel ġimgħa tal-ħajja u l-età ta' 3 xhur, f'livell ta' doża ta' 3 mg/kg darba kuljum.
English: The pharmacokinetics of emtricitabine are proportional to dose over the dose range of 25-200 mg following single or repeated administration.
Maltese: Il-farmakokinetiċi ta' emtricitabine huma proporzjonali għad-doża fuq il-medda tad-dożaġġ ta' 25-200 mg, wara l-għotja ta' darba jew ripetuta.
English: This medicinal product contains 36 mg of sodium per 24 mL, equivalent to 1.8% of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Maltese: Dan il-prodott mediċinali fih 36 mg ta' sodium f'kull 24 mL, ekwivalenti għal 1.8% tal-ammont massimu rakkomandat mill-WHO ta' 2 g sodium li għandu jittieħed kuljum minn adult.
English: This active substance is an antiretroviral medicine which is used to treat HIV infection.
Maltese: Din is-sustanza attiva hi mediċina antiretrovirali li tintuża biex tittratta l-infezzjoni ta' l-HIV.
English: How to store Emtriva
Maltese: Tiħux Emtriva
English: 15 mL
Maltese: 15-il mL
English: dizziness
Maltese: Pożoloġija
English: Psychiatric disorders: Common:
Maltese: Farmakokinetiċi intraċellulari:
English: Resistance: HIV-1 resistance to emtricitabine develops as the result of changes at codon 184 causing the methionine to be changed to a valine (an isoleucine intermediate has also been observed) of the HIV reverse transcriptase.
Maltese: Ir-reżistenza ta' l-HIV-1 għal emtricitabine tiżviluppa bħala riżultat ta' tibdil fil-kodon 184 li jikkawża li methionine tinbidel f'valine (isoleucine intermedja ġiet osservata wkoll) ta' l-HIV reverse transcriptase.
English: 18 mL
Maltese: 18-il mL
English: Table 1 below provides daily doses of Emtriva 10 mg/mL oral solution according to the degree of renal insufficiency.
Maltese: Tabella 1 t'hawn taħt tipprovdi d-dożi ta' kuljum ta' Emtriva 10 mg/mL soluzzjoni orali skond il-grad ta' insuffiċjenza renali.
English: In clinical trials of HIV infected adults, the most frequently occurring adverse reactions to emtricitabine were diarrhoea (14.0%), headache (10.2%), elevated creatine kinase (10.2%) and nausea (10.0%).
Maltese: Fi studji kliniċi fuq pazjenti adulti li kienu infettati bl-HIV, l-iktar reazzjonijiet avversi għal emtricitabine li seħħew b'mod aktar frekwenti kienu dijarrea (14.0%), uġigħ ta' ras (10.
English: Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) which works by interfering with the normal working of an enzyme (reverse transcriptase) that is essential for the HIV virus to reproduce itself.
Maltese: Emtricitabine hu impeditur tan-nucleoside reverse transcriptase (NRTI) u jaħdem billi jinterferixxi mal-ħidma normali ta' enzima (reverse transcriptase) li hi essenzjali biex il-virus ta' l-HIV jirriproduċi lilu nnifsu.
English: A measuring cup is provided (see section 6.5).
Maltese: Tazza tal-kejl hija pprovduta (ara sezzjoni 6.5).
English: Also, emtricitabine did not inhibit uridine-5'-diphosphoglucuronyl transferase, the enzyme responsible for glucuronidation.
Maltese: Emtricitabine, ukoll, ma impedixxix lill-enzima uridine-5'-diphosphoglucuronyl transferase, li hija responsabbli għall-glukoronidazzjoni.
English: Blood and lymphatic system disorders: Common:
Maltese: Disturbi tad-demm u tas-sistema limfatika:
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.
Maltese: Informazzjoni dettaljata dwar din il-mediċina tinsab fuq is-sit elettroniku tal-Aġenzija Ewropeja għallMediċini http://www.ema.europa.eu.
English: Emtriva comes in bottles or blister packs containing 30 capsules.
Maltese: Emtriva tiġi fi fliexken jew f'pakketti ta' folji li fihom 30 kapsula.