FrancophonIA/ELRC3.0 huggingface dataset:
English: Hulio 40 mg solution for injection in single-use vial (type I glass), fitted with rubber stoppers (fluoropolymer-laminated butyl rubber), aluminium crimps and flip-off seals.
Slovenian: Zdravilo Hulio 40 mg raztopina za injiciranje v viali za enkratno uporabo (steklo tipa I) z gumijasto zaporko (butilna guma, prevlečena s fluoropolimerom), aluminijastim zamaškom in tesnilom ''flip-off''.
English: After 12 weeks of therapy, patients who had received adalimumab in period A were rerandomised in period B to 1 of 3 treatment groups (adalimumab 40 mg every week, adalimumab 40 mg every other week, or placebo from week 12 to week 35).
Slovenian: Po 12 tednih terapije so bolnike, ki so prejemali adalimumab v obdobju A, ponovno randomizirali v obdobju B v eno izmed treh skupin zdravljenja (adalimumab 40 mg vsak teden, adalimumab 40 mg vsak drugi teden ali placebo od 12. do 35. tedna).
English: On rare occasions, a specific and severe type of lymphoma has been observed in some patients taking adalimumab.
Slovenian: V redkih primerih so pri bolnikih, ki dobivajo adalimumab, opazili specifično in resno obliko limfoma.
English: Psoriatic arthritis and axial spondyloarthritis including ankylosing spondylitis There is no relevant use of adalimumab in the paediatric population for the indications of ankylosing spondylitis and psoriatic arthritis.
Slovenian: Psoriatični artritis in aksialni spondiloartritis, vključno z ankiloznim spondilitisom Uporaba adalimumaba pri pediatrični populaciji za indikaciji ankilozni spondilitis in psoriatični artritis ni primerna.
English: Table 23: Maintenance of Clinical Remission and Response (Percent of Patients) Placebo
Slovenian: Preglednica 23: Vzdrževanje klinične remisije in odziva (odstotek bolnikov) placebo
English: If these medicines do not work well enough, patients will be given Hulio.
Slovenian: Če ta zdravila ne delujejo dovolj dobro, bodo bolniki prejeli zdravilo Hulio.
English: o DO NOT use the pen if the medication is not near the Fill Marker.
Slovenian: ◦ Injekcijskega peresnika NE uporabljajte, če zdravilo ni v bližini oznake napolnjenosti.
English: Tell your child's doctor immediately if your child gets symptoms like changes in vision, weakness in arms or legs or numbness or tingling in any part of the body.
Slovenian: Otrokovemu zdravniku takoj povejte, če se pri vašem otroku pojavijo simptomi, kot so spremembe vida, šibkost rok ali nog ali pa odrevenelost ali mravljinčenje v katerem koli delu telesa.
English: Push the plunger rod all the way down.
Slovenian: Nosilec bata potisnite do konca dol.
English: In the larger AS study I with 315 patients, results showed statistically significant improvement of the signs and symptoms of ankylosing spondylitis in patients treated with adalimumab compared to placebo.
Slovenian: Rezultati obsežnejše študije AS I pri 315 bolnikih so pri bolnikih, ki so dobivali adalimumab, pokazali statistično značilno izboljšanje znakov in simptomov ankilozirajočega spondilitisa v primerjavi s placebom.
English: b 2-sided P value from log rank test. c NE = not estimable.
Slovenian: b 2-stranska vrednost P testa log-rank.
English: RA study III evaluated 619 patients with moderately to severely active rheumatoid arthritis who were ≥ 18 years old, and who had an ineffective response to methotrexate at doses of 12.5 to 25 mg or have been intolerant to 10 mg of methotrexate every week.
Slovenian: V študiji revmatoidnega artritisa III je bilo ocenjenih 619 bolnikov z zmerno do zelo aktivnim revmatoidnim artritisom, starih ≥ 18 let, ki se niso učinkovito odzvali na odmerke metotreksata od 12,5 do 25 mg ali niso prenašali 10 mg metotreksata vsak teden.
English: In Psoriasis Studies I and II, a primary endpoint was the proportion of patients who achieved a PASI 75 response from baseline at week 16 (see Tables 17 and 18).
Slovenian: V študijah psoriaze I in II je bila primarna končna točka delež bolnikov, ki so od izhodišča do 16. tedna dosegli PASI 75 (glejte preglednici 17 in 18).
English: • any infection (including tuberculosis, blood poisoning, influenza, cellulitis, shingles, ear infections, tooth infections, cold sores, reproductive tract infections, urinary tract infection,
Slovenian: • vse okužbe (vključno s tuberkulozo, zastrupitvijo krvi, gripo, celulitisom, pasovcem, okužbami ušes, okužbami zob, herpesom, okužbami reproduktivnih organov, okužbami sečil, glivičnimi okužbami, okužbami sklepov);
English: In the Phase 3 trial of adalimumab in patients with paediatric Crohn's disease which evaluated efficacy and safety of two body weight adjusted maintenance dose regimens following body weight adjusted induction therapy up to 52 weeks of treatment, ALT elevations ≥ 3 x ULN occurred in 2.6% (5/192) of patients of whom 4 were receiving concomitant immunosuppressants at baseline.
Slovenian: V preskušanju faze 3 z adalimumabom pri bolnikih s pediatrično Crohnovo boleznijo, kjer so ocenjevali učinkovitost in varnost dveh telesni masi prilagojenih vzdrževalnih režimov odmerjanja, ki sta sledila telesni masi prilagojenemu začetnemu zdravljenju do 52 tednov zdravljenja, so se pojavila zvišanja ALT ≥ 3 × ULN pri 2,6 % (5/192) bolnikov, od katerih so štirje sočasno prejemali imunosupresive ob začetku preskušanja.
English: The most commonly reported adverse reactions are infections (such as nasopharyngitis, upper respiratory tract infection and sinusitis), injection site reactions (erythema, itching, haemorrhage, pain or swelling), headache and musculoskeletal pain.
Slovenian: Najpogosteje poročani neželeni učinki so okužbe (kot so nazofaringitis, okužbe zgornjih dihal in sinusitis), reakcije na mestu injiciranja (eritem, srbenje, hemoragija, bolečina ali otekanje), glavobol in mišično-skeletne bolečine.
English: Exposure-response relationships between adalimumab concentration and efficacy in paediatric patients with severe chronic plaque psoriasis were established for PASI 75 and PGA clear or minimal, respectively.
Slovenian: Razmerji med izpostavljenostjo in odzivom med koncentracijo adalimumaba in učinkovitostjo pri pediatričnih bolnikih s hudo kronično psoriazo v plakih sta bili določeni za PASI 75 (PASI - Psoriasis Area and Severity Index) in za PGA (PGA - Physician's Global Assessment) čisto ali minimalno.
English: In RA studies I-IV, adalimumab-treated patients achieved statistically significant ACR 20 and 50 responses compared to placebo as early as one to two weeks after initiation of treatment.
Slovenian: V študijah revmatoidnega artritisa I-IV so z adalimumabom zdravljeni bolniki v primerjavi s prejemniki placeba dosegli statistično značilna odziva 20 in 50 po ACR že en do dva tedna po začetku zdravljenja.
English: Hulio is used to treat hidradenitis suppurativa in adolescents from 12 years of age.
Slovenian: Zdravilo Hulio se uporablja za zdravljenje hidradenitis suppurativa pri mladostnikih, starejših od 12 let.
English: Medication
Slovenian: Zdravilo
English: 1 sterile needle
Slovenian: 1 sterilna igla
English: • Once syringe is firmly attached to the needle, remove the clear needle packaging.
Slovenian: • Ko je brizga trdno nameščena na iglo, odstranite prozorno ovojnino igle.
English: Placebo / MTXc n=200
Slovenian: placebo/M TXc n = 200
English: Tell your doctor immediately if you get symptoms like changes in your vision, weakness in your arms or legs or numbness or tingling in any part of the body.
Slovenian: Zdravniku takoj povejte, če se pri vas pojavijo simptomi, kot so spremembe vida, šibkost rok ali nog ali pa odrevenelost ali mravljinčenje v katerem koli delu telesa.
English: Adalimumabb/ MTXc n=207
Slovenian: adalimumabb/M TXc n = 207
English: Table 16: Ps Study IV Efficacy Results at 16, 26 and 52 weeks Endpoint
Slovenian: Preglednica 16: Študija psoriaze IV - rezultati učinkovitosti po 16, 26 in 52 tednih Končna točka
English: There is insufficient evidence of the efficacy of adalimumab in patients with ankylosing spondylitislike psoriatic arthropathy due to the small number of patients studied.
Slovenian: Zaradi majhnega števila proučevanih bolnikov ni dovolj dokazov o učinkovitosti adalimumaba pri bolnikih s psoriatično artropatijo, podobno ankilozirajočemu spondilitisu.
English: If you forget to give your child an injection, you should inject the next dose of Hulio as soon as you remember.
Slovenian: Če pozabite dati svojemu otroku injekcijo zdravila Hulio, mu morate odmerek zdravila Hulio injicirati takoj, ko se spomnite.
English: Hulio is administered every other week via subcutaneous injection.
Slovenian: Zdravilo Hulio se odmerja vsak drugi teden v obliki subkutane injekcije.
English: If your doctor has told you that you (or your child) have an intolerance to some sugars or if you have been diagnosed with hereditary fructose intolerance (HFI), a rare genetic disorder in which a person cannot break down fructose, talk to your doctor before you (or your child) take or receive this medicine.
Slovenian: Če vam je zdravnik povedal, da imate (ali ima vaš otrok) intoleranco za nekatere sladkorje, ali če so vam odkrili dedno intoleranco za fruktozo (HFI), redko genetsko bolezen, pri kateri telo ne more razgraditi fruktoze, se posvetujte s svojim zdravnikom, preden začnete jemati (ali začne vaš otrok jemati) to zdravilo.
English: Polyarticular juvenile idiopathic arthritis from 2 years of age The recommended dose of Hulio for patients with polyarticular juvenile idiopathic arthritis from 2 years, of age is based on body weight (Table 1).
Slovenian: Poliartikularni juvenilni idiopatski artritis od 2. leta starosti Priporočeni odmerek zdravila Hulio pri bolnikih s poliartikularnim juvenilnim idiopatskim artritisom, starih 2 leti in več, temelji na telesni masi (preglednica 1).
English: week 12 results showed statistically significant improvement of the signs and symptoms of active nr-axSpA in patients treated with adalimumab compared to placebo (Table 14).
Slovenian: Rezultati so v 12. tednu pokazali statistično pomembno izboljšanje znakov in simptomov aktivnega nraxSpA pri bolnikih, ki so bili zdravljeni z adalimumabom v primerjavi s placebom (preglednica 14).
English: What Hulio is and what it is used for What you need to know before giving your child Hulio How to use Hulio
Slovenian: Kaj je zdravilo Hulio in za kaj ga uporabljamo Kaj morate vedeti, preden bo vaš otrok prejel zdravilo Hulio Kako uporabljati zdravilo Hulio Možni neželeni učinki
English: Time to Treatment Failure in Studies UV I and UV II
Slovenian: Preglednica 24: Čas do neuspeha zdravljenja v študijah UV I in UV II
English: • 1 sharps disposal container (not included in Hulio pack)
Slovenian: • 1 vsebnik za odlaganje ostrih predmetov (ni priložen pakiranju zdravila Hulio);
English: By week 68, patients receiving continuous adalimumab treatment showed statistically significant greater improvement of the signs and symptoms of active nr-axSpA as compared to patients allocated to treatment withdrawal during the double-blind period of the study (Table 15).
Slovenian: Rezultati do 68. tedna so pokazali statistično značilno izboljšanje znakov in simptomov aktivnega nr axSpA pri bolnikih, ki so neprekinjeno prejemali adalimumab, v primerjavi z bolniki, ki so bili v skupini za prenehanje zdravljenja v dvojno slepem obdobju študije (preglednica 15).
English: General disorders and administration site conditions*
Slovenian: Splošne težave in spremembe na mestu aplikacije:*
English: Use one of the alcohol pads to wipe the stopper and then place the vial on a flat surface.
Slovenian: Uporabite enega od alkoholnih zložencev in z njim obrišite zaporko.
English: Across all treatment groups, the mean baseline PASI score was 18.9 and the baseline Physician's Global Assessment (PGA) score ranged from “moderate” (53% of subjects included) to “severe” (41%) to “very severe” (6%).
Slovenian: V vseh terapevtskih skupinah je bila povprečna izhodiščna ocena PASI 18,9, izhodiščna zdravnikova globalna ocena (PGA - Physician's Global Assessment) pa je segala od ''zmerne'' (53 % vključenih preiskovancev) do ''hude'' (41 %) in ''zelo hude'' (6 %).
English: Table 7: Distribution of patients by age and adalimumab dose received during the OL LI phase
Slovenian: Preglednica 7: Porazdelitev bolnikov po starosti in odmerku adalimumaba, ki so ga dobivali med odprto uvajalno fazo
English: Hulio is used to treat children and adolescents aged 2 to 17 years with chronic non-infectious uveitis who have inflammation affecting the front of the eye.
Slovenian: Zdravilo Hulio se uporablja za zdravljenje otrok in mladostnikov, starih od 2 do 17 let, s kroničnim neinfekcijskim uveitisom, kjer vnetje prizadene sprednji del očesa.
English: Hulio is also used to treat severe plaque psoriasis in children and adolescents aged 4 to 17 years whom medicines applied to the skin and treatment with UV light have either not worked very well or are not suitable.
Slovenian: Zdravilo Hulio se uporablja tudi za zdravljenje hude luskavice v plakih pri otrocih in mladostnikih, starih od 4 do 17 let, pri katerih zdravila, nanesena na kožo, in zdravljenje z UV-svetlobo niso dovolj dobro delovali ali pa niso primerni.
English: • Hulio can be used during breast-feeding.
Slovenian: Zdravilo Hulio se lahko uporablja med dojenjem.
English: In Psoriasis Studies I and II, a primary endpoint was the proportion of patients who achieved a PASI 75 response from baseline at week 16 (see Tables 14 and 15).
Slovenian: V študijah psoriaze I in II je bila primarna končna točka delež bolnikov, ki so od izhodišča do 16. tedna dosegli PASI 75 (glejte preglednici 14 in 15).
English: Keep this Patient Reminder Card with you or your child at all times and for 4 months after your child's last injection of Hulio.
Slovenian: To opozorilno kartico za bolnika imejte vedno pri sebi ali naj jo ima pri sebi vaš otrok, kar velja še 4 mesece po zadnji injekciji zdravila Hulio, ki jo otrok prejme.
English: Preparing the Hulio dose for injection
Slovenian: Priprava odmerka zdravila Hulio za injiciranje
English: For patients who develop the signs and symptoms such as fever, malaise, weight loss, sweats, cough, dyspnoea, and/or pulmonary infiltrates or other serious systemic illness with or without concomitant shock an invasive fungal infection should be suspected and administration of Hulio should be promptly discontinued.
Slovenian: Če se pri bolniku pojavijo znaki in simptomi, kot so zvišana telesna temperatura, splošno slabo počutje, hujšanje, znojenje, kašelj, dispneja in/ali pljučni infiltrati ali druga resna sistemska bolezen s sočasnim šokom ali brez njega, je treba posumiti na invazivno glivično okužbo.
English: This risk may increase if your lung function is reduced.
Slovenian: Tveganje je lahko večje, če imate oslabljeno delovanje pljuč.
English: What Hulio is and what it is used for What you need to know before you use Hulio How to use Hulio
Slovenian: Kaj je zdravilo Hulio in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Hulio Kako uporabljati zdravilo Hulio Možni neželeni učinki
English: JSNd score a methotrexate b 95% confidence intervals for the differences in change scores between methotrexate and adalimumab.
Slovenian: Ocena erozij Ocena ZSŠd a metotreksat b 95 % intervali zaupanja za razlike v spremembi ocen med metotreksatom in adalimumabom c na podlagi analize rangov d zožitev sklepne špranje
English: The safety and efficacy of adalimumab were assessed in randomised, double-blind, placebo-controlled studies and an open-label extension study in adult patients with moderate to severe hidradenitis suppurativa (HS) who were intolerant, had a contraindication or an inadequate response to at least a 3month trial of systemic antibiotic therapy.
Slovenian: Varnost in učinkovitost adalimumaba so raziskali v randomiziranih, dvojno slepih študijah, kontroliranih s placebom, in v odprti podaljšani študiji pri odraslih bolnikih z zmerno do hudo obliko hidradenitis suppurativa (HS), ki imajo intoleranco, kontraindikacijo ali se ne odzovejo zadovoljivo na vsaj 3-mesečno preskušanje sistemske antibiotične terapije.
English: Your child's doctor may decide to stop treatment.
Slovenian: Morda se bo odločil, da otrokovo zdravljenje prekine.
English: Vaccine
Slovenian: Cepljenje
English: Hulio is used to treat hidradenitis suppurativa in adults, and adolescents from 12 years of age.
Slovenian: Zdravilo Hulio se uporablja za zdravljenje hidradenitis suppurativa pri odraslih in mladostnikih, starejših od 12 let.
English: The rate (95% confidence interval) of nonmelanoma skin cancers was 8.8 (6.0, 13.0) per 1,000 patient-years among adalimumab-treated patients and 3.2 (1.3, 7.6) per 1,000 patient-years among control patients.
Slovenian: Delež (95-% interval zaupanja) nemelanomskih kožnih rakov je bil 8,8 (6,0; 13,0) na 1000 bolnikov-let med bolniki, ki so prejemali adalimumab, in 3,2 (1,3; 7,6) na 1000 bolnikov-let med kontrolnimi bolniki.
English: Gently squeeze the injection site to create a raised area, and hold that area firmly.
Slovenian: Nežno stisnite kožo na injekcijskem mestu, da se površina dvigne, in jo čvrsto držite.
English: • pale complexion, dizziness, persistent fever, bruising or bleeding very easily.
Slovenian: • bledica, omotica, dolgotrajno zvišana telesna temperatura, hiter nastanek podplutb ali krvavitve.
English: When Hulio therapy is initiated, a loading dose of 40 mg for patients < 30 kg or 80 mg for patients ≥ 30 kg may be administered one week prior to the start of maintenance therapy.
Slovenian: Na začetku zdravljenja z zdravilom Hulio se lahko pri bolnikih < 30 kg uporabi polnilni odmerek 40 mg in pri bolnikih ≥ 30 kg polnilni odmerek 80 mg en teden pred začetkom vzdrževalnega zdravljenja.
English: In CD Study III, 854 patients received open-label 80 mg at week 0 and 40 mg at week 2.
Slovenian: V tej študiji je 854 bolnikov po odprtem protokolu dobilo 80 mg 0. teden in 40 mg 2. teden.
English: The recommended Hulio induction dose regimen for adult patients with moderately to severely active Crohn's disease is 80 mg at week 0 followed by 40 mg at week 2.
Slovenian: Priporočena shema odmerjanja zdravila Hulio med indukcijo je pri odraslih bolnikih z zmerno do hudo aktivno Crohnovo boleznijo 80 mg 0. teden in nato 40 mg 2. teden.
English: In CD Study I and CD Study II, statistically significant improvement in the disease-specific inflammatory bowel disease questionnaire (IBDQ) total score was achieved at week 4 in patients randomised to adalimumab 80/40 mg and 160/80 mg compared to placebo and was seen at weeks 26 and 56 in CD Study III as well among the adalimumab treatment groups compared to the placebo group.
Slovenian: Študiji pri Crohnovi bolezni I in II sta pokazali statistično značilno izboljšanje celotnega seštevka po vprašalniku IBDQ (vprašalnik, specifičen za vnetno bolezen črevesa) do 4. tedna pri bolnikih, randomiziranih na shemi z adalimumabom 80/40 mg in 160/80 mg v primerjavi s placebom; razliko 26. in 56. teden je v skupinah, zdravljenih z adalimumabom, v primerjavi s placebom pokazala tudi študija pri Crohnovi bolezni III.
English: EU/1/18/1319/001 1 pack EU/1/18/1319/002 2 pack EU/1/18/1319/003 6 pack
Slovenian: EU/1/18/1319/004 1 pakiranje EU/1/18/1319/005 2 pakiranji EU/1/18/1319/006 6 pakiranj
English: • trouble breathing or swallowing;
Slovenian: • težave pri dihanju ali požiranju;
English: Hulio is indicated for the treatment of adults with severe active ankylosing spondylitis who have had an inadequate response to conventional therapy.
Slovenian: Zdravilo Hulio je indicirano za zdravljenje hudega aktivnega ankilozirajočega spondilitisa pri odraslih, ki se na konvencionalno terapijo ne odzovejo ustrezno.
English: Table 17: Ps Study I (REVEAL) - Efficacy Results at 16 weeks Placebo N=398 n (%)
Slovenian: Preglednica 17: Študija pri psoriazi I (REVEAL) - Rezultati učinkovitosti po 16 tednih placebo n = 398 n (%)
English: • itching, inflammation of the skin (including eczema);
Slovenian: • srbenje, vnetje kože (vključno z ekcemom);
English: Hulio is indicated for the treatment of moderately to severely active Crohn's disease in paediatric patients (from 6 years of age) who have had an inadequate response to conventional therapy including primary nutrition therapy and a corticosteroid and/or an immunomodulator, or who are intolerant to or have contraindications for such therapies.
Slovenian: Zdravilo Hulio je indicirano za zdravljenje zmerno do hudo aktivne Crohnove bolezni pri pediatričnih bolnikih (od 6. leta starosti), ki se ne odzovejo zadovoljivo na konvencionalno zdravljenje, vključno s primarno prehransko terapijo in kortikosteroidom in/ali imunomodulatorjem, ali pri tistih, ki imajo intoleranco ali kontraindikacije za tako zdravljenje.
English: Table 11: Distribution of patients by age and adalimumab dose received during the OL LI
Slovenian: Preglednica 11: Porazdelitev bolnikov po starosti in odmerku adalimumaba, ki so ga dobivali med odprto uvajalno fazo
English: Hepatosplenic T-cell lymphoma1) Merkel cell carcinoma (neuroendocrine carcinoma of the skin)1)
Slovenian: redki levkemija1) neznana pogostnost hepatosplenični T-celični limfom1), karcinom Merklovih celic (nevroendokrini karcinom kože)1)
English: Note: P = Placebo (Number at Risk); H = adalimumab (Number at Risk).
Slovenian: Opomba: P = placebo (število rizičnih preiskovancev); H = adalimumab (število rizičnih preiskovancev)
English: • Check the expiry date printed on the vial.
Slovenian: • Preverite rok uporabnosti zdravila, ki je natisnjen na viali.
English: Preparing the Hulio injection
Slovenian: Priprava injekcije zdravila Hulio
English: Hulio is intended for the treatment of the following inflammatory diseases: - rheumatoid arthritis; - polyarticular juvenile idiopathic arthritis; - enthesitis-related arthritis; - ankylosing spondylitis; - axial spondyloarthritis without radiographic evidence of ankylosing spondylitis; - psoriatic arthritis; - psoriasis; - hidradenitis suppurativa; - Crohn's disease; - ulcerative colitis; - non-infectious uveitis in adults and children.
Slovenian: Zdravilo Hulio je namenjeno za zdravljenje naslednjih vnetnih bolezni: - revmatoidnega artritisa, - poliartikularnega juvenilnega idiopatskega artritisa, - artritisa, povezanega z entezitisom, - ankilozirajočega spondilitisa, - aksialnega spondiloartritisa brez radiografskega dokaza za ankilozirajoči spondilitis, - psoriatičnega artritisa, - luskavice (psoriaze), - hidradenitis suppurativa, - Crohnove bolezni, - ulceroznega kolitisa, - neinfekcijskega uveitisa pri odraslih in otrocih.
English: Amongst those who responded at week 16 (n=144), the Pediatric ACR 30/50/70/90 responses were maintained for up to six years in the OLE phase in patients who received adalimumab throughout the study.
Slovenian: Med bolniki, ki so se odzvali 16. teden (n = 144), so se odzivi ''Pediatric ACR'' 30/50/70/90 v odprti podaljšani fazi ohranili do 6 let pri tistih, ki so ves čas študije dobivali adalimumab.
English: If these medicines do not work well enough, you will be given Hulio.
Slovenian: Če ta zdravila ne delujejo dovolj dobro, boste dobili zdravilo Hulio.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON - VIAL MULTIPACK (WITH BLUE BOX)
Slovenian: PODATKI NA ZUNANJI OVOJNINI ZUNANJA ŠKATLA - VEČKRATNO PAKIRANJE VIAL (Z MODRIM OKENCEM)
English: If your child has mild heart failure and are being treated with Hulio, your child's heart failure status must be closely monitored by the doctor.
Slovenian: Če ima vaš otrok blago srčno popuščanje in se zdravi z zdravilom Hulio, mora zdravnik natančno nadzorovati stanje srčnega popuščanja pri otroku.
English: Hulio Dose for Paediatric Patients with Crohn's disease
Slovenian: Preglednica 4: Odmerjanje zdravila Hulio pri pediatričnih bolnikih s Crohnovo boleznijo
English: Recheck the doctor's prescription for the correct prescribed amount.
Slovenian: Ponovno preverite, kolikšno količino je predpisal zdravnik.
English: • Take a single vial box out of the fridge at least 30 minutes before you intend to use it to allow the contents to reach room temperature.
Slovenian: • Škatlo z eno vialo vzemite iz hladilnika najmanj 30 minut pred predvideno uporabo, da se vsebina segreje na sobno temperaturo.