FrancophonIA/ELRC3.0 huggingface dataset:
English: Macugen is a solution which is injected into the eye. Pegaptanib, the active substance of this medicine, inhibits the activity of the factor involved in the abnormal formation of new blood vessels in the eye, known as Vascular Endothelial Growth Factor165 (VEGF165).
Croatian: Pegaptanib, djelatna tvar ovog lijeka, inhibira aktivnost faktora uključenog u abnormalno stvaranje novih krvnih žila u oku, poznatog kao vaskularni endotelni faktor165 rasta ( VEGF165).
English: • nightmare, depression, deafness, vertigo
Croatian: • noćne more, depresiju, gluhoću,vrtoglavicu
English: The safety data described below summarise all procedure and adverse reactions in the 295 patients in the 0.3 mg treatment group.
Croatian: Sigurnosni podaci opisani u nastavku sažeto prikazuju sve nuspojave povezane s postupkom injiciranja i s lijekom u 295 bolesnika koji su primali dozu od 0,3 mg.
English: Pegaptanib is a pegylated modified oligonucleotide that binds with high specificity and affinity to extracellular Vascular Endothelial Growth Factor (VEGF165) inhibiting its activity.
Croatian: Pegaptanib je pegilirani modificirani oligonukleotid koji se s visokom specifičnošću i afinitetom veže za izvanstanični vaskularni endotelni faktor rasta (VEGF165) te inhibira njegovu aktivnost.
English: After intravitreal and intravenous administrations of radiolabeled pegaptanib to rabbits, the highest concentrations of radioactivity (excluding the eye for the intravitreal dose) were obtained in the kidney.
Croatian: Nakon intravitrealne i intravenske primjene radioaktivno označenog pegaptaniba u kunića, najviše koncentracije radioaktivnosti (izuzevši oko kod intravitrealne primjene) postignute su u bubrezima.
English: If you are affected, do not drive or use machines until this resolves.
Croatian: Ako Vam je vid zamagljen, nemojte upravljati vozilom ni rukovati strojevima dok se simptomi ne povuku.
English: The two trials enrolled patients, including all neovascular AMD lesion subtypes (25% predominantly classic, 39% occult with no classic and 36% minimally classic), lesion sizes up to 12 disc areas, of which up to 50% could be comprised of subretinal haemorrhage and/or up to 25% fibrotic scar or atrophic damage.
Croatian: U navedenim dvama ispitivanjima sudjelovali su bolesnici sa svim podvrstama lezija kod neovaskularne senilne makularne degeneracije (25% bolesnika s pretežno klasičnim lezijama, 39% bolesnika s okultnim lezijama bez klasičnih i 36% bolesnika s minimalno klasičnim lezijama) i veličinama lezija do 12 površina diska.
English: Twenty-four hours after intravitreous administration of a radiolabeled dose of pegaptanib to both eyes of rabbits, radioactivity was mainly distributed in vitreous humour, retina and aqueous humour.
Croatian: Dvadeset i četiri sata nakon intravitrealne primjene radioaktivno označene doze pegaptaniba u oba oka kunića, radioaktivnost se prvenstveno raspodijelila u staklovinu, mrežnicu i očnu vodicu.
English: In the 40 mg/kg/day group, pegaptanib concentrations in the amniotic fluid were 0.05% of the maternal plasma levels.
Croatian: U skupini koja je primala 40 mg/kg na dan koncentracije pegaptaniba u amnijskoj tekućini iznosile su 0,05% koncentracija u plazmi majke.
English: Jankovcova 1569/2c 170 00 Praha 7
Croatian: PharmaSwiss Česká republika s.r.o. Jankovcova 1569/2c 170 00 Praha 7
English: • bleeding that occurs around the eye (periorbital bleeding)
Croatian: • krvarenje oko oka (periorbitalno krvarenje)
English: CAUTION: Since the pre-filled syringe contains more medicinal product volume (250-270 microlitres) than the recommended dose (90 microlitres), a part of the volume contained in the syringe has to be discarded prior to the administration.
Croatian: OPREZ: Budući da napunjena štrcaljka sadrži veći volumen lijeka (250-270 mikrolitara) od preporučene doze (90 mikrolitara), dio volumena u štrcaljki treba ispustiti prije primjene lijeka.
English: No data are available to evaluate male or female mating or fertility indices.
Croatian: Nema dostupnih podataka za ocjenu parenja ni indeksa plodnosti u mužjaka ili ženki.
English: The selective inhibition in animals with pegaptanib proved as effective at suppressing pathological neovascularisation as pan-VEGF inhibition, however pegaptanib spared the normal vasculature whereas pan-VEGF inhibition did not.
Croatian: U životinja se selektivna inhibicija pegaptanibom pokazala jednako djelotvornom u supresiji patološke neovaskularizacije kao i općenita inhibicija VEGF-a međutim, pegaptanib pri tome nije oštetio normalno krvožilje, a općenita inhibicija VEGF-a jest.
English: Verteporfin photodynamic therapy (PDT) was permitted in patients with predominantly classic lesions at the discretion of the investigators.
Croatian: Prema odluci ispitivača, fotodinamska terapija (PDT) verteporfinom bila je dopuštena u bolesnika s pretežno klasičnim lezijama.
English: At doses below 0.5 mg/eye, pegaptanib plasma concentrations do not likely exceed 10 ng/ml.
Croatian: Kod doza manjih od 0,5 mg po oku nije vjerojatno da bi koncentracije pegaptaniba u plazmi mogle premašiti 10 ng/ml.
English: Please seek immediate medical help if you experience any of the following soon after the injection: sudden onset of breathing difficulty or wheezing, swollen mouth, face, hands or feet, itching skin, fainting, rapid pulse, stomach cramps, nausea, vomiting or diarrhoea.
Croatian: Odmah zatražite liječničku pomoć ako ubrzo nakon injekcije primijetite: iznenadnu pojavu tegoba s disanjem ili piskanje pri disanju, oticanje usta, lica, šaka ili stopala, svrbež kože, nesvjesticu, ubrzani puls, grčeve u želucu, mučninu, povraćanje ili proljev.
English: 4.7 Effects on ability to drive and use machines Macugen has a minor influence on the ability to drive and use machines due to the possible temporary visual blurring after administration of Macugen by intravitreal injection.
Croatian: Macugen malo utječe na sposobnost upravljanja vozilima i rada sa strojevima zbog mogućeg nastanka privremeno zamagljenog vida nakon intravitrealne injekcije lijeka.
English: SLOWLY depress the plunger to eliminate all the bubbles and to expel the excess drug so that the top edge of the 3rd rib on the plunger stopper aligns with the pre-printed black dosing line (See Fig 2, below).
Croatian: POLAKO gurajte klip prema gore kako bi se uklonili mjehurići i izbacio višak lijeka tako da se gornji rub trećeg navoja čepa klipa poravna s otisnutom crnom linijom za doziranje (vidjeti Sliku 2 u nastavku).
English: In the clinical trial, the overall frequency of non-ocular haemorrhages, an adverse event potentially related to systemic VEGF (vascular endothelial growth factor) inhibition, was slightly increased in intravitreal VEGF inhibitor-treated patients.
Croatian: U kliničkim ispitivanjima, ukupna učestalost neokularnih hemoragija, štetnog događaja potencijalno povezanog sa sistemskom inhibicijom VEGF-a (vaskularnog endotelnog faktora rasta), bila je blago povišena u bolesnika liječenih intravitrealnim VEGF inhibitorom.
English: Patients were randomised to receive sham or 0.3 mg, 1 mg or 3 mg pegaptanib administered as intravitreal injections every 6 weeks for 48 weeks.
Croatian: Bolesnici su randomizirani u skupinu koja je primala placebo postupak ili u skupine koje su primale 0,3 mg, 1 mg ili 3 mg pegaptaniba u obliku intravitrealne injekcije svakih 6 tjedana tijekom razdoblja od 48 tjedana.
English: • bleeding in the eye or the internal portion of the eye (vitreous)
Croatian: • krvarenje u oko ili unutarnji dio oka (staklovinu)
English: • increased sensitivity to light, appearance of flashing lights
Croatian: • pojačanu osjetljivost na svjetlost, bljeskanje pred očima
English: Prior to the administration, the syringe should be removed from the plastic clip and the tip cap removed.
Croatian: Prije primjene štrcaljku treba odvojiti od plastične kvačice i ukloniti zatvarač vrha.
English: The syringe should be checked with the needle pointing up for the presence of bubbles.
Croatian: Štrcaljku treba pregledati iglom okrenutom prema gore kako bi se utvrdila eventualna prisutnost mjehurića.
English: Arterial thromboembolic events (ATEs) are adverse events potentially related to systemic VEGF inhibition.
Croatian: Događaji arterijske tromboembolije su štetni događaji potencijalno povezani sa sistemskom VEGF inhibicijom.
English: • inflammation of your eye or of the outer surface of the eye
Croatian: • upalu oka ili vanjske površine oka
English: • disorder of the jelly portion inside the eye (vitreous disorder), such as displacement or tear
Croatian: • poremećaj želatinozne tvari u oku (poremećaj staklovine) poput pomaka ili razderotina
English: Uncommon asthenopia, blepharitis, conjunctivitis allergic, corneal deposits, eye haemorrhage, eyelids pruritus, keratitis, vitreous haemorrhage, pupillary reflex impaired, corneal abrasion, retinal exudates, eyelid ptosis, retinal scar, chalazion, corneal erosion, decreased intraocular pressure, injection site reaction, injection site vesicles, retinal detachment, corneal disorder, retinal artery occlusion, retinal tear, ectropion, eye movement disorder, eyelid irritation, hyphaema, pupillary disorder, iris disorder, ocular icterus, anterior uveitis, deposit eye, iritis, optic nerve cupping, pupillary deformity, retinal vein occlusion, and vitreous prolapse
Croatian: Poremećaji oka vrlo često upala prednje očne sobice, bol u oku, povišen intraokularni tlak, točkasti keratitis, plutajuće čestice u staklovini i zamućenje staklovine često neuobičajen osjet u oku, katarakta, konjunktivalno krvarenje, hiperemija konjunktive, edem konjunktive, konjunktivitis, distrofija rožnice, oštećenje epitela rožnice, poremećaj epitela rožnice, edem rožnice, suho oka, endoftalmitis, iscjedak iz oka, upala oka, iritacija oka, svrbež oka, crvenilo oka, oticanje oka, edem vjeđe, pojačano suzenje, degeneracija makule, midrijaza, nelagoda u oku, očna hipertenzija, periorbitalni hematom, fotofobija, fotopsija, krvarenja mrežnice, zamagljen vid, smanjena oštrina vida, smetnje vida, odvajanje staklovine i poremećaj manje često astenopija, blefaritis, alergijski konjunktivitis, talozi u rožnici, krvarenje u oko, svrbež vjeđa, keratitis, krvarenje u staklovinu, oštećenje zjeničnog refleksa, abrazija rožnice, eksudati na mrežnici, ptoza vjeđe, ožiljak na mrežnici, halazion, erozija rožnice, snižen intraokularni tlak, reakcija na mjestu injekcije, vezikule na mjestu injekcije, odignuće mrežnice, poremećaj rožnice, okluzija mrežnične arterije, razderotina mrežnice, ektropij, poremećaj očne pokretljivosti, iritacija vjeđe, hifema, poremećaj zjenice, poremećaj šarenice, očni ikterus, prednji uveitis, talozi u oku, iritis, atrofija vidnog živca, deformacija zjenice, okluzija vene mrežnice i prolaps staklovine
English: Summary of Mean Changes in Visual Acuity from Baseline to Weeks 6, 12, 54 and 102 (LOCF) EOP 1004
Croatian: Sažeti prikaz srednjih promjena oštrine vida od početnih vrijednosti do 6., 12., 54. i 102. tjedna
English: Occasionally, an infection or bleeding in the eye can occur after Macugen injection (in the next two weeks).
Croatian: Nakon injekcije lijeka Macugen ponekad može doći do infekcije ili krvarenja u oku (unutar dva tjedna nakon injekcije).
English: • inflammation of the eye (iritis)
Croatian: • upalu oka (iritis)
English: • irritation and inflammation of the skin, hair colour changes, rash, itching,
Croatian: • nadraženost i upalu kože, promjene boje kose, osip, svrbež
English: It is not known whether Macugen is excreted in human milk.
Croatian: Nije poznato izlučuje li se Macugen u majčino mlijeko.
English: There is a theoretical risk of arterial thromboembolic including stroke and myocardial infarction events following intravitreal use of VEGF inhibitors.
Croatian: Postoji teoretski rizik od događaja arterijske tromboembolije uključujući moždani udar i infarkt miokarda nakon intravitrealne primjene VEGF inhibitora.
English: Pegaptanib pharmacokinetics have not been studied in patients with hepatic impairment.
Croatian: Farmakokinetika pegaptaniba nije ispitana u bolesnika s oštećenjem jetrene funkcije.
English: Moreover patients should be closely monitored for vitreous haemorrhage and endophthalmitis in the two weeks following the injection.
Croatian: Nadalje, tijekom dva tjedna nakon injekcije bolesnike treba pažljivo pratiti zbog moguće pojave krvarenja u staklovinu i endoftalmitisa.
English: In some patients the pressure inside the treated eye may increase for a short period directly after the injection.
Croatian: U nekih bolesnika odmah nakon injekcije može doći do kratkotrajnog povišenja tlaka u liječenu oku.
English: Each pack contains a pouch in a carton, containing a pre-filled syringe, Type I glass, filled with 0.250.27 ml of solution, sealed with an elastomeric plunger stopper and a pre-attached plunger rod, held by a plastic clip.
Croatian: Svako pakiranje u kutiji sadrži vrećicu s napunjenom štrcaljkom, staklo tip 1, napunjenu s 0,25-0,27 ml otopine, zatvorenu elastomernim čepom klipa pričvršćenim na potisni klip kojeg drži plastična kvačica.
English: Mean Change in Visual Acuity Over Time; Year 1; ITT (LOCF)
Croatian: Srednja promjena oštrine vida kroz vrijeme; 1. godina; populacija predviđena za liječenje (engl. intentto treat, ITT) (prijenos zadnje zabilježene vrijednosti (engl. last observation carried forward, LOCF))
English: Pegaptanib 0.3 mg showed treatment benefit regardless of baseline lesion subtype, lesion size and visual acuity as well as age, gender, iris pigmentation and prior and/or baseline PDT usage.
Croatian: Liječenje pegaptanibom u dozi od 0,3 mg imalo je pozitivne učinke neovisno o početnoj podvrsti lezije, veličini lezije i oštrini vida, kao i o dobi, spolu, pigmentaciji šarenice te prethodnoj fotodinamskoj terapiji i/ili fotodinamskoj terapiji na početku liječenja.
English: For additional information regarding sodium content of Macugen, see section
Croatian: Za dodatne informacije o sadržaju natrija u lijeku Macugen vidjeti dio 2. Kako Macugen izgleda i sadržaj pakiranja
English: The systemic exposure to pegaptanib is expected to be very low after ocular administration.
Croatian: Očekuje se vrlo niska sistemska izloženost pegaptanibu nakon okularne primjene.
English: Delivers a single dose of 0.3 mg in 90 microliters Pack of one pre-filled syringe, a plunger stopper and a pre-attached plunger rod.
Croatian: Sadrži jednu dozu od 0,3 mg u 90 mikrolitara Pakiranje s jednom napunjenom štrcaljkom, čepom klipa i pričvršćenim potisnikom klipa.
English: Uncommon hypertension, aortic aneurysm
Croatian: Krvožilni poremećaji manje često hipertenzija, aneurizma aorte
English: Method of administration For intravitreal injection use only.
Croatian: Način primjene Samo za intravitrealnu primjenu injekcijom.
English: sp. j. Tel.: +48 17 865 51 00
Croatian: Valeant sp. z o.o. sp. j. Tel.: +48 17 865 51 00
English: The physician safety brochure should contain the following key elements: a) The intravitreal procedure as it was performed in the pivotal clinical studies, along with any technical improvements b) Use of povidone iodine c) Performing lid scrubs d) Use of anaesthetic to ensure patient comfort e) Sterile techniques to minimize the risk of infection f) Use of antibiotics g) Techniques for the intravitreal injection h) Key signs and symptoms of intravitreal injection related adverse events including endophthalmitis,
Croatian: Sigurnosna brošura za liječnika treba sadržavati sljedeće ključne elemente: a) intravitrealni postupak kako je proveden u pivot kliničkim ispitivanjima skupa s tehničkim poboljšanjima b) primjenu povidon jodida c) čišćenje očnih vjeđa za zahvat d) primjenu anestetika kako bi se osigurala udobnost bolesnika e) sterilne tehnike za minimizaciju rizika od infekcije f) primjenu antibiotika g) tehnike za davanje intravitrealne injekcije h) ključne znakove i simptome štetnih događaja povezanih s intravitrealnim injekcijama uključujući endoftalmitis, povišeni intraokularni tlak, ozljedu mrežnice, intraokularno krvarenje, traumatsku kataraktu, preosjetljivost i injiciranja suvišnog volumena i) liječenje intraokularnog tlaka j) liječenje endoftalmitisa k) razumijevanje čimbenika rizika uključenih u razvoj endoftalmitisa l) prijavljivanje ozbiljnih nuspojava (pomoćni podsjetnik)
English: Each pack contains a pouch in a carton containing a 1 ml pre-filled syringe, Type 1 glass, sealed with an elastomeric (brombutyl rubber) plunger stopper and a pre-attached plunger rod, held by a plastic clip.
Croatian: Svako pakiranje u kutiji sadrži vrećicu s napunjenom štrcaljkom od 1 ml od stakla tip 1, zatvorenu elastomernim (brombutil guma) čepom klipa pričvršćenim na potisni klip kojeg drži plastična kvačica.
English: • decreased vision
Croatian: • oslabljen vid
English: In rabbits, pegaptanib is eliminated as parent drug and metabolites primarily in the urine.
Croatian: U kunića se pegaptanib eliminira prvenstveno kroz mokraću u obliku osnovnog spoja i metabolita.
English: Macugen should be inspected visually for particulate matter and discoloration prior to administration (see section 6.6).
Croatian: Prije primjene Macugen treba vizualno pregledati kako bi se utvrdila eventualna prisutnost čestica i promjena boje (vidjeti dio 6.6).
English: Macugen is used for the treatment of the wet form of age-related macular degeneration (AMD).
Croatian: Macugen se koristi za liječenje vlažnog oblika senilne makularne degeneracije.
English: Ear and labyrinth disorders Uncommon deafness, Meniere's disease aggravated, vertigo
Croatian: Poremećaji uha i labirinta manje često gluhoća, pogoršanje Ménièreove bolesti, vrtoglavica
English: On average, the treatment benefit was maintained at 102 weeks with continuing preservation of visual acuity for patients re-randomized to continue pegaptanib.
Croatian: U prosjeku je u bolesnika randomiziranih za nastavak liječenja pegaptanibom korist liječenja bila održana do 102. tjedna, pri čemu je kontinuirano očuvana oštrina vida.
English: Each single dose pre-filled syringe delivers a dose of 0.3 mg pegaptanib in 90 microlitres.
Croatian: Jedna jednodozna napunjena štrcaljka sadrži dozu od 0,3 mg pegaptaniba u 90 mikrolitara.
English: • blood in your eye, discoloured eye, deposit eye
Croatian: • krv u oku, promjenu boje oka, taloge u oku
English: • small particles or spots in your vision (vitreous floaters or opacities).
Croatian: • male čestice ili točkice u vidnom polju (plutajuće čestice u staklovini i zamućenje staklovine).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION One pre-filled syringe provides a usable amount to deliver a single dose of 90 microlitres containing pegaptanib sodium, corresponding to 0.3 mg of the free acid form of the oligonucleotide.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedna napunjena štrcaljka sadrži dostatnu količinu za isporuku jedne doze od 90 mikrolitara koja sadrži pegaptanibnatrij, što odgovara 0,3 mg oligonukleotida u obliku slobodne kiseline.
English: - The active substance is pegaptanib.
Croatian: Što Macugen sadrži - Djelatna tvar je pegaptanib.
English: Adequate anaesthesia and a broad-spectrum topical microbicide should be administered prior to the injection.
Croatian: Prije injekcije treba primijeniti odgovarajuću anesteziju i antibiotik širokog spektra za topikalnu primjenu.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS POUCH containing pre-filled syringe, a plunger stopper and a pre-attached plunger rod
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE VREĆICA koja sadrži napunjenu štrcaljku, čep klipa i pričvršćen potisnik klipa
English: Pegaptanib sodium has not been adequately studied in patients with creatinine clearance below 20 ml/min.
Croatian: Nisu provedena odgovarajuća ispitivanja pegaptanib natrija u bolesnika s klirensom kreatinina manjim od 20 ml/min.
English: • clouding of the lens (cataract)
Croatian: • zamućenje leće (katarakta)
English: • inflammation of the central part of the surface of the eye (keratitis)
Croatian: • upalu središnjeg dijela površine oka (keratitis)
English: Align the third rib of the plunger stopper with the pre-printed black dosing line.
Croatian: Poravnati treći navoj na čepu klipa s otisnutom crnom linijom za doziranje.
English: Therefore, the perfusion of the optic nerve head should be verified and elevation of intraocular pressure should be managed appropriately post injection.
Croatian: Stoga nakon injekcije treba provjeriti perfuziju glave vidnog živca i na odgovarajući način liječiti povišenje intraokularnog tlaka.
English: - The other ingredients are sodium chloride, monobasic sodium phosphate monohydrate, dibasic sodium phosphate heptahydrate, sodium hydroxide and hydrochloric acid (for pH adjustment) and water for injections.
Croatian: - Drugi sastojci su natrijev klorid, natrijev dihidrogenfosfat hidrat, natrijev hidrogenfosfat heptahidrat, natrijev hidroksid i kloridna kiselina (za podešavanje pH) i voda za injekcije.
English: • eye inflammation, tears, inflammation of the conjunctiva (conjunctivitis), dryness, eye discharge, eye irritation, itching of the eye, eye redness or enlargement of the pupil
Croatian: • upalu oka, suzenje, upalu konjunktive (konjunktivitis), suhoću oka, iscjedak iz oka nadraženost oka, svrbež oka, crvenilo oka ili proširene zjenice
English: • small lump on your eyelid due to inflammation (chalazion)
Croatian: • malu kvržicu na vjeđi izazvanu upalom (halacion)
English: Following the injection, transient increases in intraocular pressure were seen in Macugen treated patients.
Croatian: Nakon injekcije su u bolesnika liječenih lijekom Macugen primijećena prolazna povišenja intraokularnog tlaka.
English: The patient information should contain the following key elements: m) Key signs and symptoms of serious adverse events associated with the intravitreal injection procedure including endophthalmitis, increased intraocular pressure, retinal injury, intraocular haemorrhage, traumatic cataract, hypersensitivity and injection of excess volume n) When to seek urgent attention from the health care provider
Croatian: Informacije za bolesnika trebaju sadržavati sljedeće ključne elemente: m) ključne znakove i simptome ozbiljnih štetnih događaja povezanih s postupkom davanja intravitrealne injekcije uključujući endoftalmitits, povišeni intraokularni tlak, ozljedu mrežnice,
English: Cases of serious allergic reaction, including anaphylactic reaction and angioedema of which symptoms are described below, has been reported soon after the injection.
Croatian: Neposredno nakon primjene injekcije prijavljeni su slučajevi teške alergijske reakcije, uključujući anafilaktičku reakciju i angioedem, čiji su simptomi opisani niže u tekstu.
English: Drug interaction studies have not been conducted with Macugen.
Croatian: Nisu provedena ispitivanja interakcija lijeka Macugen s drugim lijekovima.
English: • small deposits on the eye or on the surface of the eye (cornea), deposits in the back of the eye,
Croatian: • male taloge na oku ili površini oka (rožnici), taloge u stražnjem dijelu oka
English: PharmaSwiss EOOD Тел.
Croatian: PharmaSwiss UAB Tel.
English: Common (may affect up to 1 in 10 people)
Croatian: Često (mogu se javiti u do 1 do 10 osoba)
English: • eversion of the eyelid, eye movement disorder, eyelid irritation
Croatian: • izvrnuće vjeđe, poremećaj pokretljivosti oka, nadraženost vjeđe
English: You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects you can help provide more information on the safety of this medicine.
Croatian: Nuspojave također možete prijaviti izravno putem nacionalnog sustava prijave nuspojava navedenog u Dodatku V.
English: • occlusion of the vein at the back of the eye
Croatian: • okluziju (zatvaranje) vene u stražnjem dijelu oka
English: • inflammation of the higher respiratory tract, vomiting, indigestion
Croatian: • upalu gornjih dišnih puteva, povraćanje, probavne smetnje
English: • small erosion on the central part of the surface of the eye (cornea)
Croatian: • malu eroziju središnjeg dijela površine oka (rožnice)
English: Macugen 0.3 mg solution for injection Pegaptanib
Croatian: Macugen 0,3 mg otopina za injekciju pegaptanib