FrancophonIA/ELRC3.0 huggingface dataset:
English: Peripheral infusion time longer than 30 minutes, leads to a higher incidence of infusion site reactions and thrombophlebitis.
Slovenian: Če periferno infundiranje traja več kot 30 minut, to poveča pojavnost reakcij na mestu infundiranja in tromboflebitisa.
English: 24 gastro-resistant tablets 96 gastro-resistant tablets
Slovenian: 24 gastrorezistentnih tablet 96 gastrorezistentnih tablet
English: • severe kidney problems - signs include passing more or less urine that is a different colour than usual
Slovenian: • hude težave z ledvicami - med znaki so izločanje več ali manj urina, ki je drugačne barve kot po navadi
English: ECOFF values do not equate to clinical breakpoints.
Slovenian: Vrednosti ECOFF niso enake kliničnim mejnim vrednostim.
English: noxafil tablets
Slovenian: noxafil tablete
English: • efavirenz and fosamprenavir used to treat HIV infection.
Slovenian: • efavirenz in fosamprenavir, ki se uporabljata za zdravljenje okužbe s HIV.
English: Renal clearance is a minor elimination pathway, with 14 % of the radiolabelled dose excreted in urine (< 0.2 % of the radiolabelled dose is parent compound).
Slovenian: Ledvični očistek je manj pomembna pot izločanja; v urinu se izloči 14 % radioaktivno označenega odmerka (< 0,2 % radioaktivno označenega odmerka predstavlja matična spojina).
English: The majority (377/600, [63 %]) of patients included had Acute Grade 2 or 3 or chronic extensive (195/600, [32.5 %]) GVHD at study start.
Slovenian: Večina (377/600, [63 %]) v študijo vključenih bolnikov je imela na začetku študije akutno GVHD stadija 2 ali 3 ali kronično obsežno GVHD (195/600, [32,5 %]).
English: • inflammation or pain at injection site
Slovenian: • vnetje ali bolečine na mestu injiciranja
English: New diagnosis of acute myelogenous leukaemia was the most common underlying condition (435/602, [72 %]).
Slovenian: Najpogostejša osnovna bolezen je bila na novo diagnosticirana akutna mieloična levkemija (435/602, [72 %]).
English: Q1 Q2 Q3 Q4
Slovenian: Kv1 Kv2 Kv3 Kv4
English: Cenexi HSC, 2, rue Louis Pasteur; 14200 Hérouville St Clair, France
Slovenian: Cenexi HSC, 2, rue Louis Pasteur; 14200 Hérouville St Clair, Francija
English: Posaconazole inhibits the enzyme lanosterol 14α-demethylase (CYP51), which catalyses an essential step in ergosterol biosynthesis.
Slovenian: Posakonazol zavira encim lanosterol-14α-demetilazo (CYP51), ki katalizira eno od ključnih stopenj v biosintezi ergosterola.
English: If not used immediately, the solution can be stored up to 24 hours at 2°C-8°C (in a refrigerator).
Slovenian: Če ni uporabljeno takoj, je raztopino mogoče shranjevati do 24 ur pri temperaturi od 2 °C do 8 °C (v hladilniku).
English: It is recommended to exercise caution due to the potential for higher plasma exposure.
Slovenian: Priporočljiva je previdnost zaradi možne večje plazemske izpostavljenosti.
English: • pseudoaldosteronism, which results in high blood pressure with a low potassium level (shown in blood test)
Slovenian: • psevdoaldosteronizem, ki povzroči zvišan krvni tlak z nizko koncentracijo kalija (se pokaže pri preiskavah krvi)
English: • Do not take a double dose to make up for a forgotten dose.
Slovenian: • Ne vzemite dvojnega odmerka, da bi nadomestili izpuščeni odmerek.
English: Caution is warranted on any sign or symptom of thromboembolic events (see sections 4.8 and 5.3).
Slovenian: Potrebno je biti pozoren na pojav kakršnega koli znaka ali simptoma tromboemboličnih dogodkov (glejte poglavji 4.8 in 5.3).
English: Note: In clinical trials, multiple peripheral infusions given through the same vein resulted in infusion site reactions (see section 4.8).
Slovenian: Opomba: V kliničnih preskušanjih je večkratno periferno infundiranje v isto veno povzročilo reakcije na mestu infundiranja (glejte poglavje 4.8).
English: • heartburn (a burning sensation in the chest rising up to the throat)
Slovenian: • zgaga (pekoč občutek v prsnem košu, ki se dviguje proti grlu)
English: This finding was not seen in monkeys dosed for one year.
Slovenian: Tega niso opazili pri opicah, ki so zdravilo dobivale eno leto.
English: Results from clinical studies in prophylaxis of Invasive Fungal Infections Study
Slovenian: Izsledki kliničnih študij profilakse invazivnih glivnih okužb Študija
English: Prophylaxis in GVHD Study 316
Slovenian: Profilaksa pri GVHD Študija 316
English: • cisapride (used to treat stomach problems)
Slovenian: • cisaprid (za zdravljenje težav z želodcem)
English: • have any problem with potassium, magnesium or calcium levels in your blood
Slovenian: • če imate kakšne težave s koncentracijo kalija, magnezija ali kalcija v krvi.
English: No pharmacokinetic data are available from paediatric patients less than 8 years of age.
Slovenian: Farmakokinetičnih podatkov za pediatrične bolnike, mlajše od 8 let, ni na voljo.
English: To improve absorption of posaconazole, whenever possible it should be taken during or immediately after food or a nutritional drink (see section 3 “How to take Noxafil”).
Slovenian: Da se izboljša absorpcija posakonazola ga, kadar koli je le mogoče, vzemite med ali takoj po jedi ali zaužitju prehranskega dopolnila v obliki napitka (glejte poglavje 3 “Kako jemati zdravilo Noxafil”).
English: Posaconazole is slowly eliminated with a mean half-life (t½) of 35 hours (range 20 to 66 hours).
Slovenian: Posakonazol se izloča počasi, s srednjo razpolovno dobo (t½) 35 ur (razpon od 20 do 66 ur).
English: Similarly, in the prophylaxis studies, the mean steady-state posaconazole average concentration (Cav) was comparable among ten adolescents (13-17 years of age) to Cav achieved in adults (≥ 18 years of age).
Slovenian: Podobno je bila v študijah profilaktične uporabe povprečna koncentracija posakonazola v stanju dinamičnega ravnovesja (Cav) pri desetih mladostnikih (starih od 13 do 17 let) primerljiva Cav, doseženi pri odraslih (starih ≥ 18 let).
English: You may need to have blood tests while you are taking this medicine.
Slovenian: Morda vam bodo morali med jemanjem tega zdravila opravljati preiskave krvi.
English: There are currently insufficient data to set clinical breakpoints for Aspergillus spp.
Slovenian: Trenutno ni dovolj podatkov za določitev kliničnih mejnih vrednosti za Aspergillus spp.
English: At exposures lower than those obtained at therapeutic doses in humans, posaconazole caused skeletal variations and malformations, dystocia, increased length of gestation, reduced mean litter size and postnatal viability.
Slovenian: Pri izpostavljenostih, manjših od izpostavljenosti, doseženih s terapevtskimi odmerki pri človeku, je posakonazol povzročil spremembe skeleta in malformacije, distocijo, podaljšanje gestacije, manjše povprečno število mladičev in manjšo postnatalno življenjsko sposobnost.
English: A switch to oral administration is recommended as soon as the patients' condition allows (see section 4.4).
Slovenian: Prehod na peroralno uporabo je priporočljiv takoj, ko to dopušča bolnikovo stanje (glejte poglavje 4.4).
English: You will be given Noxafil:
Slovenian: Zdravilo Noxafil boste dobili:
English: • Do not use this medicine after the expiry date which is stated on the label.
Slovenian: • Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na ovojnini.
English: In Study 316, overall mortality was similar (POS, 25 %; FLU, 28 %); however, the proportion of IFIrelated deaths was significantly lower in the POS group (4/301) compared with the FLU group (12/299; P= 0.0413).
Slovenian: V študiji 316 je bila celokupna umrljivost podobna (POS 25 %, FLU 28 %), vendar je bil odstotek z invazivno glivno okužbo povezanih smrti v skupini s POS značilno manjši (4/301) kot v skupini s FLU (12/299, p = 0,0413).
English: Other medicines and Noxafil
Slovenian: Druga zdravila in zdravilo Noxafil
English: A key secondary endpoint was the incidence of proven/probable IFIs during the on-treatment period (first dose to last dose of study medicinal product + 7 days).
Slovenian: Ključni sekundarni opazovani dogodek je bila pojavnost dokazanih oziroma verjetnih invazivnih glivnih okužb med obdobjem zdravljenja (od prvega odmerka do zadnjega odmerka proučevanega zdravila + 7 dni).
English: Therefore, trough concentrations that fall in the upper part of the usual therapeutic range should be targeted and careful attention should be paid to clinical signs and symptoms, laboratory parameters and tissue biopsies.
Slovenian: Zato mora biti ciljna najnižja koncentracija sirolimusa v zgornjem delu običajnega terapevtskega razpona in posebno pozornost je treba nameniti kliničnim znakom in simptomom, laboratorijskim parametrom in tkivnim biopsijam.
English: Overall Response Success by Species All mycologically confirmed Aspergillus spp.
Slovenian: Skupni odziv Uspešnost po vrstah Vse mikološko potrjene Aspergillus spp.
English: Moreover, sparse PK samples were collected at several days during steady state before the next dose (Cmin) for a larger subject population.
Slovenian: Poleg tega so redko razporejene farmakokinetične vzorce odvzeli ob več dneh v stanju dinamičnega ravnovesja pred naslednjim odmerkom (Cmin) za večjo populacijo preiskovancev.
English: • water retention (oedema)
Slovenian: • zastajanje vode (edemi)
English: Posaconazole is slowly absorbed and slowly eliminated with a large apparent volume of distribution (1,774 litres) and is highly protein bound (> 98 %), predominantly to serum albumin.
Slovenian: Posakonazol se počasi absorbira in počasi izloča, z velikim navideznim porazdelitvenim volumnom (1.774 litrov) in je v veliki meri vezan na beljakovine (> 98 %), predvsem na serumski albumin.
English: Prophylaxis in Neutropenia Study 1899
Slovenian: Profilaksa pri nevtropeniji Študija 1899
English: Food The absorption of posaconazole is significantly increased by food (see sections 4.2 and 5.2).
Slovenian: Hrana Absorpcija posakonazola se bistveno poveča s hrano (glejte poglavji 4.2 in 5.2).
English: In patients with moderate or severe renal impairment (creatinine clearance <50 mL/min), accumulation of the intravenous vehicle, Betadex Sulfobutyl Ether Sodium (SBECD), is expected to occur.
Slovenian: Pri bolnikih z zmerno ali hudo okvaro ledvic (očistek kreatinina < 50 ml/min) je treba pričakovati kopičenje intravenskega vehikla, natrijevega sulfobutiletra betaciklodekstrina (SBECD).
English: • This medicine does not require any special storage conditions.
Slovenian: • Za shranjevanje tega zdravila niso potrebna posebna navodila.
English: Patients who develop abnormal liver function tests during Noxafil therapy must be routinely monitored for the development of more severe hepatic injury.
Slovenian: Bolnike, pri katerih se med zdravljenjem z zdravilom Noxafil pojavijo nenormalni izvidi jetrnih testov, je treba rutinsko spremljati glede nastanka hujše poškodbe jeter.
English: Oral formulations of Noxafil should be used in these patients unless an assessment of the benefit/risk to the patient justifies the use of Noxafil concentrate for solution for infusion.
Slovenian: Pri teh bolnikih je treba uporabljati peroralne oblike zdravila Noxafil, razen če ocena razmerja koristi in tveganja za posameznega bolnika upravičuje uporabo zdravila Noxafil koncentrat za raztopino za infundiranje.
English: See Table 4 and 5 for results from both studies.
Slovenian: Za izsledke obeh študij glejte preglednici 4 in 5.
English: Store in a refrigerator at 2°C-8°C.
Slovenian: Shranjujte v hladilniku pri temperaturi od 2 °C do 8 °C.
English: The following information was derived from data with posaconazole oral suspension or early tablet formulation.
Slovenian: Naslednje informacije temeljijo na podatkih, pridobljenih med uporabo peroralne suspenzije ali zgodnje oblike tablet posakonazola.
English: Posaconazole is absorbed with a median tmax of 3 hours (fed patients).
Slovenian: Posakonazol se absorbira z mediano vrednostjo tmax 3 ure (nahranjeni bolniki).
English: Noxafil concentrate for solution for infusion will always be prepared and given to you by a healthcare professional.
Slovenian: Zdravilo Noxafil koncentrat za raztopino za infundiranje bo vedno pripravil in vam ga dal zdravstveni delavec.
English: Contains sodium.
Slovenian: Vsebuje natrij.
English: See Table 5 and 6 for results from both studies.
Slovenian: Za izsledke obeh študij glejte preglednici 5 in 6.
English: Noxafil 100 mg gastro-resistant tablets are packaged in a PVC/ polychlorotrifluoroethylene laminate blister with push-through aluminium lidding.
Slovenian: Noxafil 100 mg gastrorezistentne tablete so pakirane v pretisni omot iz PVC/poliklorotrifluoroetilen laminata z aluminijasto folijo, skozi katero se potisne tableta.
English: • heart failure or heart attack which could lead to the heart stopping beating and death, heart rhythm problems, with sudden death
Slovenian: • srčno popuščanje ali srčni infarkt, ki lahko povzroči zastoj srca in smrt; motnje srčnega ritma z nenadno smrtjo
English: Cav Range (ng/mL)
Slovenian: Razpon Cav (ng/ml)
English: One subject (<1 %) had a predicted Cav below 500 ng/mL and 19 % of the subjects had a predicted Cav above 2,500 ng/mL.
Slovenian: En preiskovanec (< 1 %) je imel predvideno Cav pod 500 ng/ml in 19 % preiskovancev je imelo predvideno Cav nad 2.500 ng/ml.
English: • Infections in the mouth or throat area (known as “thrush”) caused by fungi called Candida, which were not previously treated.
Slovenian: • okužb v predelu ust ali žrela (znane pod imenom “sor”), ki jih povzroča gliva Candida in katere predhodno še niso bile zdravljene.
English: Epidemiological Cut-off (ECOFF) values for Aspergillus spp.
Slovenian: Epidemiološke mejne vrednosti (ECOFF) za Aspergillus spp.
English: From a microbiological point of view, once admixed, the product should be used immediately.
Slovenian: Z mikrobiološkega stališča je treba zdravilo uporabiti takoj, ko je pripravljeno.
English: • Aseptically transfer 16.7 mL of posaconazole to an intravenous bag (or bottle) containing a compatible admixture diluent (see below for list of diluents) using the volume ranging from 150 mL to 283 mL depending on the final concentration to be achieved (not less than 1 mg/mL and not greater than 2 mg/mL).
Slovenian: • Aseptično prenesite 16,7 ml posakonazola v intravensko vrečko (ali steklenico), ki vsebuje od 150 ml do 283 ml kompatibilne mešanice topila (glejte spodaj seznam topil), odvisno od končne koncentracije, ki jo je treba doseči (naj ne bo nižja od 1 mg/ml in naj ne presega 2 mg/ml).
English: • Cardiomyopathy, especially in the presence of cardiac failure
Slovenian: • kardiomiopatija, še posebej v primeru srčnega popuščanja,
English: • Store in a refrigerator (2C-8C).
Slovenian: • Shranjujte v hladilniku (2 °C do 8 °C).
English: Coadministration of posaconazole with sirolimus is not recommended and should be avoided whenever possible.
Slovenian: Sočasna uporaba posakonazola s sirolimusom ni priporočljiva in se ji je treba izogniti, če je le mogoče.
English: A measuring spoon is provided with each bottle for measuring 2.5 and 5 mL doses of the oral suspension.
Slovenian: Vsaki steklenički je priložena odmerna žlička za odmerjanje 2,5 in 5 ml peroralne suspenzije.
English: If a dose of Noxafil has been forgotten
Slovenian: Če je bil odmerek zdravila Noxafil pozabljen
English: • difficulty breathing
Slovenian: • težko dihanje
English: • If a central venous catheter is not available, a single infusion may be administered through a peripheral venous catheter with a volume to achieve a dilution of approximately 2 mg/mL.
Slovenian: • Če centralni venski kateter ni na voljo, je mogoče enkratno intravensko infuzijo dati po perifernem venskem katetru v količini, s katero se doseže koncentracija približno 2 mg/ml.
English: • have had an allergic reaction to another antifungal medicine such as ketoconazole, fluconazole,
Slovenian: • če ste imeli alergijsko reakcijo na kakšno drugo protiglivno zdravilo, npr. na ketokonazol,
English: Multiple doses of posaconazole administered via a peripheral venous catheter were associated with thrombophlebitis (60 % incidence).
Slovenian: Večkratni odmerki posakonazola, uporabljeni po perifernem venskem katetru, so bili povezani s tromboflebitisom (pojavnost 60 %).
English: See “Other medicines and Noxafil” below for more information including information on other medicines which may interact with Noxafil.
Slovenian: Glejte "Druga zdravila in zdravilo Noxafil" (spodaj) za več informacij, vključno z informacijami o drugih zdravilih, ki lahko medsebojno delujejo z zdravilom Noxafil.
English: As observed with other azole antifungal agents, these effects on reproduction were considered to be due to a treatment-related effect on steroidogenesis.
Slovenian: Tako kot pri drugih azolskih antimikotikih so ti učinki na razmnoževanje šteli za posledico z zdravljenjem povezanega učinka na steroidogenezo.
English: This medicine is available in a single use glass vial closed with bromobutyl rubber stopper and aluminium seal.
Slovenian: Zdravilo je na voljo v stekleni viali za enkratno uporabo, zaprti z zamaškom iz brombutilne gume in aluminijasto zaporo.
English: Noxafil is used to prevent and treat many different fungal infections.
Slovenian: Zdravilo Noxafil se uporablja za preprečevanje in zdravljenje številnih različnih vrst glivnih okužb.
English: Noxafil tablets are the preferred formulation to optimize plasma concentrations and generally provide higher plasma drug exposures than Noxafil oral suspension.
Slovenian: Zdravilo Noxafil v obliki tablet je primernejša oblika za optimiziranje plazemske koncentracije in na splošno zagotavlja večjo plazemsko izpostavljenost zdravilu kot zdravilo Noxafil peroralna suspenzija.
English: The effect of posaconazole on sirolimus in patients is unknown, but is expected to be variable due to the variable posaconazole exposure in patients.
Slovenian: Učinek posakonazola na sirolimus pri bolnikih ni znan, vendar je treba pričakovati, da je spremenljiv zaradi spremenljive izpostavljenosti posakonazolu med bolniki.
English: Study 5615 was conducted in a similar patient population to that previously studied in the pivotal posaconazole oral suspension clinical program.
Slovenian: Študijo 5615 so izvedli pri podobni populaciji bolnikov, kot je bila pred tem preučena v ključnem kliničnem programu s peroralno suspenzijo posakonazola.
English: Posaconazole was not genotoxic in in vitro and in vivo studies.
Slovenian: Posakonazol v študijah in vitro in in vivo ni bil genotoksičen.
English: Most of the cases of aspergillosis were considered to be refractory to prior therapy in both the posaconazole group (88 %) and in the external control group (79 %).
Slovenian: Večina primerov aspergiloze je veljala za odporne na predhodno zdravljenje tako v skupini, ki je prejemala posakonazol (88 %), kot v zunanji kontrolni skupini (79 %).
English: itraconazole or voriconazole.
Slovenian: flukonazol, itrakonazol ali vorikonazol.
English: • rifabutin and rifampicin (used to treat certain infections).
Slovenian: • rifabutin in rifampicin (uporabljata se za zdravljenje določenih okužb).
English: 105 mL of oral suspension in a bottle (glass amber type IV) closed with a plastic child-resistant cap (polypropylene) and a measuring spoon (polystyrene) with 2 graduations: 2.5 mL and 5 mL.
Slovenian: 105 ml peroralne suspenzije v steklenički (rjavo steklo tipa IV), zaprti s plastično za otroke varno zaporko (iz polipropilena) in odmerno žličko (iz polistirena) z 2 oznakama: 2,5 ml in 5 ml.
English: In Study 1899, a significant decrease in all cause mortality in favour of posaconazole was observed [POS 49/304 (16 %) vs. FLU/ITZ 67/298 (22 %) p= 0.048].
Slovenian: V študiji 1899 so značilno manjšo celokupno umrljivost zaradi vseh vzrokov opazili v skupini, ki je prejemala posakonazol [POS 49/304 (16 %) v primerjavi s FLU/ITZ 67/298 (22 %), p = 0,048].
English: • hearing problems
Slovenian: • težave s sluhom
English: * Based on adverse reactions observed with the oral suspension, gastro-resistant tablets, and concentrate for solution for infusion.
Slovenian: * Na podlagi neželenih učinkov, opaženih s peroralno suspenzijo, gastrorezistentnimi tabletami in koncentratom za raztopino za infundiranje.
English: Contains also liquid glucose.
Slovenian: Vsebuje tudi tekočo glukozo.
English: • nerve damage (neuropathy)
Slovenian: • okvara živcev (nevropatija)
English: The safety of posaconazole concentrate for solution for infusion has been assessed in 268 patients in clinical trials.
Slovenian: Varnost posakonazola v koncentratu za raztopino za infundiranje so v kliničnih preskušanjih ocenili pri 268 bolnikih.
English: • have a weakness of the heart muscle or heart failure
Slovenian: • če imate šibkost srčne mišice ali srčno popuščanje.
English: However, if it is almost time for your next dose, take your dose when it is due.
Slovenian: Če pa je že skoraj čas za naslednji odmerek, tega vzemite ob rednem času.
English: This medicine can also be used to prevent fungal infections in adults who are at high risk of getting a fungal infection, such as:
Slovenian: To zdravilo se lahko uporabi tudi za preprečevanje glivnih okužb pri odraslih, ki imajo veliko tveganje za takšne okužbe, na primer:
English: • through a plastic tube placed in your vein (intravenous infusion)
Slovenian: • po plastični cevki, nameščeni v veno (intravenska infuzija),
English: • fits (convulsions)
Slovenian: • napadi krčev (konvulzije)
English: Based on pharmacokinetic data in 10 of these paediatric patients, the pharmacokinetic profile appears to be similar to patients ≥ 18 years of age.
Slovenian: Na podlagi farmakokinetičnih podatkov pri 10 od teh pediatričnih bolnikov je farmakokinetični profil videti podoben kot pri bolnikih, starih ≥ 18 let.
English: The clinical significance of this finding is unknown; therefore, the use of posaconazole concentrate for solution for infusion to patients under 18 years of age is not recommended (see section 4.2).
Slovenian: Klinični pomen tega izsledka ni znan, zato uporaba posakonazola v koncentratu za raztopino za infundiranje ni priporočljiva pri bolnikih, mlajših od 18 let (glejte poglavje 4.2).
English: Pharmacokinetic modelling with an oral tablet formulation suggests that patients weighing greater than 120 kg may have lower posaconazole exposure.
Slovenian: Farmakokinetično modeliranje z obliko peroralnih tablet kaže, da je lahko izpostavljenost posakonazolu manjša pri bolnikih, ki tehtajo več kot 120 kg.
English: Subjects achieved a mean predicted Cav at steady state of 1,970 ng/mL.
Slovenian: Preiskovanci so dosegli povprečno predvideno Cav v stanju dinamičnega ravnovesja 1.970 ng/ml.
English: • Equilibrate the refrigerated vial of Noxafil to room temperature.
Slovenian: • Pustite, da se ohlajena viala z zdravilom Noxafil ogreje na sobno temperaturo.
English: Posaconazole may increase the plasma concentration of ergot alkaloids (ergotamine and dihydroergotamine), which may lead to ergotism.
Slovenian: Posakonazol lahko poveča plazemsko koncentracijo alkaloidov ergot (ergotamina in dihidroergotamina) in to lahko povzroči ergotizem.
English: • pain, back or neck pain, pain in arms or legs
Slovenian: • bolečine, bolečine v hrbtu ali v vratu, bolečine v rokah ali nogah
English: • medicines used to decrease stomach acid such as cimetidine and ranitidine or omeprazole and similar medicines that are called proton pump inhibitors.
Slovenian: • zdravila, ki se uporabljajo za zmanjševanje količine želodčne kisline, kot so cimetidin in ranitidin ali omeprazol ter podobna zdravila, ki jih imenujemo zaviralci protonske črpalke.
English: Rare: the following may affect up to 1 in 1,000 people
Slovenian: Redki: pojavijo se lahko pri največ 1 od 1.000 oseb
English: Additionally, twelve patients 13-17 years of age received posaconazole oral suspension 600 mg/day for prophylaxis of invasive fungal infections (Studies 316 and 1899).
Slovenian: Poleg tega je dvanajst bolnikov, starih od 13 do 17 let, prejemalo peroralno suspenzijo posakonazola v odmerku 600 mg/dan za profilakso invazivnih glivnih okužb (študiji 316 in 1899).