FrancophonIA/ELRC3.0 huggingface dataset:
English: The most frequently reported adverse reactions in clinical trials were gastrointestinal disorders, including nausea (very common), diarrhoea (very common) and vomiting (common).
Croatian: Najčešće prijavljene nuspojave tijekom kliničkih ispitivanja bile su gastrointestinalni poremećaji, uključujući mučninu (vrlo često), proljev (vrlo često) i povraćanje (često).
English: Use semaglutide once a week Write the weekday you choose to inject I injected my weekly dose on the below dates subcutaneous use
Croatian: Primjenjujte semaglutid jedanput na tjedan Zapišite dan u tjednu koji ste odabrali za davanje injekcije Moja tjedna doza injicirana je na datume u nastavku
English: Appetite, energy intake and food choice
Croatian: Apetit, unos energije i odabir hrane
English: See section 2, ‘Warning and precautions' for information on increased risk of low blood sugar and section 4 for the warning signs of low blood sugar.
Croatian: „Upozorenja i mjere opreza“ za informacije o povećanom riziku niske razine šećera u krvi i dio 4. za znakove upozorenja na nisku razinu šećera u krvi.
English: The effect of semaglutide on cardiac repolarization was tested in a thorough QTc trial.
Croatian: Učinak semaglutida na repolarizaciju srca ispitan je tijekom detaljnog QTc ispitivanja.
English: During treatment with this medicine, you may feel sick (nausea) or be sick (vomiting), or have diarrhoea.
Croatian: Tijekom liječenja ovim lijekom možete osjetiti mučninu ili povraćati ili imati proljev.
English: There are limited data from the use of semaglutide in pregnant women.
Croatian: Postoje ograničeni podaci o primjeni semaglutida u trudnica.
English: Table 1 Adverse reactions from long-term controlled phase 3a trials including the cardiovascular outcomes trial
Croatian: Tablica 1 Nuspojave iz dugotrajnih kontroliranih ispitivanja faze 3a, uključujući ispitivanje kardiovaskularnih ishoda
English: If so, the full dose will not be delivered.
Croatian: U tom slučaju nećete primiti cijelu dozu.
English: For diastolic blood pressure, there were no significant differences between semaglutide and comparators.
Croatian: Kad je riječ o dijastoličkom krvnom tlaku, nije bilo značajnih razlika između semaglutida i lijekova za usporedbu.
English: • Caregivers must be very careful when handling used needles to prevent needle injury and crossinfection.
Croatian: • Osobe koje skrbe za bolesnika moraju biti osobito oprezne pri rukovanju rabljenim iglama kako bi spriječile ozljedu iglom i križnu infekciju.
English: What Ozempic contains
Croatian: Što Ozempic sadrži
English: Always watch the dose counter to know how many mg you inject.
Croatian: Uvijek motrite brojčanik doze kako biste znali koliko mg injicirate.
English: Table 4 SUSTAIN 7: Results at week 40 Semaglutide 0.5 mg
Croatian: Tablica 4 SUSTAIN 7: Rezultati u 40. tjednu Semaglutid 0,5 mg
English: The total number of primary component MACE endpoints was 254, including 108 (6.6%) with semaglutide and 146 (8.9%) with placebo.
Croatian: Ukupni broj primarnih sastavnica MACE mjera ishoda bio je 254, uključujući 108 (6,6%) uz semaglutid i 146 (8,9%) uz placebo.
English: The enzyme neutral endopeptidase (NEP) is expected to be involved in the metabolism of semaglutide.
Croatian: Enzimski neutralna endopeptidaza (NEP) trebala bi sudjelovati u metabolizmu semaglutida.
English: • Do not inject Ozempic which has been frozen.
Croatian: • Ne injicirajte Ozempic koji je bio zamrznut.
English: All pharmacodynamic evaluations were performed after 12 weeks of treatment (including dose escalation) at steady state with semaglutide 1 mg once weekly.
Croatian: Sve farmakodinamičke procjene izvršene su nakon 12 tjedana liječenja (uključujući povećanje doze) u stanju dinamičke ravnoteže uz primjenu semaglutida 1 mg jedanput na tjedan.
English: Low blood sugar is more likely to happen if you also take a sulfonylurea or insulin.
Croatian: Veća je vjerojatnost da će se niska razina šećera u krvi pojaviti ako uzimate i sulfonilureju ili inzulin.
English: The glucose and appetite effects are specifically mediated via GLP-1 receptors in the pancreas and the brain.
Croatian: Učinci na glukozu i apetit posebno su posredovani putem GLP-1 receptora u gušterači i mozgu.
English: Semaglutide doses of 0.5 mg and 1 mg provide adequate systemic exposure over a body weight range of 40-198 kg.
Croatian: Doze semaglutida od 0,5 mg i 1 mg pružaju odgovarajuću sistemsku izloženost za tjelesnu težinu u rasponu od 40 do 198 kg.
English: The effect of semaglutide on fertility in humans is unknown.
Croatian: Učinak semaglutida na plodnost u ljudi nije poznat.
English: Only use the medicine in this pen as prescribed.
Croatian: Lijek u ovoj brizgalici koristite samo kako Vam je propisano.
English: After at least 4 weeks with a dose of 0.5 mg once weekly, the dose can be increased to 1 mg once weekly to further improve glycaemic control.
Croatian: Nakon najmanje 4 tjedna uz dozu od 0,5 mg jedanput na tjedan, doza se može povećati na 1 mg jedanput na tjedan kako bi se dodatno poboljšala regulacija glikemije.
English: The rodent C-cell tumours are caused by a non-genotoxic, specific GLP-1 receptor mediated mechanism to which rodents are particularly sensitive.
Croatian: Tumori C-stanica u glodavaca uzrokovani su ne-genotoksičnim, specifičnim mehanizmom posredovanim GLP-1 receptorom, na koji su glodavci osobito osjetljivi.
English: Tell your doctor if you have diabetic eye disease or if you experience eye problems during treatment with this medicine.
Croatian: Obavijestiti svog liječnika ako imate bolest oka uzrokovanu šećernom bolešću ili ako primijetite probleme s očima tijekom liječenja ovim lijekom.
English: After the first use of the pen, store below 30°C.
Croatian: Nakon prve primjene brizgalicu čuvati na temperaturi ispod 30°C.
English: If pancreatitis is suspected, semaglutide should be discontinued; if confirmed, semaglutide should not be restarted.
Croatian: Ako se sumnja na pankreatitis, treba prekinuti primjenu semaglutida, a ako se pankreatitis potvrdi, liječenje semaglutidom ne smije se ponovno započeti.
English: A prolonged period of observation and treatment for these symptoms may be necessary, taking into account the long half-life of semaglutide of approximately 1 week (see section 5.2).
Croatian: Možda će biti potrebno dulje praćenje i liječenje tih simptoma, pri čemu je potrebno uzeti u obzir dugi poluvijek semaglutida od približno 1 tjedna (vidjeti dio 5.2).
English: Ozempic should not be used if it does not appear clear and colourless or almost colourless.
Croatian: Ozempic se ne smije koristiti ako ne izgleda bistro i bezbojno ili gotovo bezbojno.
English: Select your dose
Croatian: Odaberite dozu
English: In a study with a single subcutaneous dose of radiolabelled semaglutide, it was found that the primary excretion routes of semaglutide-related material were via urine and faeces; approximately 2/3 of semaglutide-related material were excreted in urine and approximately 1/3 in faeces.
Croatian: U ispitivanju sa pojedinačnom potkožnom dozom radioaktivno obilježenog semaglutida utvrđeno je da su primarni putovi izlučivanja materijala povezanih sa semaglutidom bili putem urina i stolice; približno 2/3 materijala povezanih sa semaglutidom izlučeno je urinom, a približno 1/3 u stolici.
English: If it shows 1, at least 1 mg is left in your pen.
Croatian: Ako pokazuje 1; to znači da je najmanje 1 mg preostalo u brizgalici.
English: Ozempic should not be used if it has been frozen.
Croatian: Ozempic se ne smije koristiti ako je bio zamrznut.
English: GLP-1 receptors are also expressed in the heart, vasculature, immune system and kidneys.
Croatian: GLP-1 receptori eksprimiraju se i u srcu, krvnim žilama, imunološkom sustavu i bubrezima.
English: Severe and on-going stomach pain which could be due to acute pancreatitis If you have severe and on-going pain in the stomach area - see a doctor straight away as this could be a sign of acute pancreatitis (inflamed pancreas).
Croatian: Ako osjećate jaku i ustrajnu bol u području trbuha - odmah posjetite liječnika jer bi to mogao biti znak akutnog pankreatitisa (upala gušterače).
English: Due to species differences in yolk sac anatomy and function, and due to lack of GLP-1 receptor expression in the yolk sac of non-human primates, this mechanism is considered unlikely to be of relevance to humans.
Croatian: Zbog različite anatomije i funkcije žumanjčane vreće među vrstama te zbog nepostojanja eksprimiranja receptora GLP-1 u žumanjčanoj vreći neljudskih primata, smatra se da je malo vjerojatno da bi taj mehanizam mogao biti značajan za ljude.
English: If your pen is already in use, go to step 3 ‘Select your dose'.
Croatian: Ako je brizgalica već u upotrebi, prijeđite na 3. korak „Odabir doze“.
English: The hazard ratio [95% CI] for time to nephropathy (new onset of persistent macroalbuminuria, persistent doubling of serum creatinine, need for continuous renal replacement therapy and death due to renal disease) was 0.64 [0.46; 0.88] driven by new onset of persistent macroalbuminuria.
Croatian: Omjer hazarda [95% CI] za vrijeme do nefropatije (nova pojava trajne makroalbuminurije, trajno udvostručena vrijednost kreatinina u serumu, nužno kontinuirano bubrežno nadomjesno liječenje i smrt zbog bolesti bubrega) bio je 0,64 [0,46; 0,88] uzrokovan novom pojavom trajne makroalbuminurije.
English: For further information on administration, see section 6.6.
Croatian: Za daljnje informacije o primjeni vidjeti dio 6.6.
English: Time from randomisation (week) Ozempic
Croatian: Vrijeme od randomizacije (u tjednima) Ozempic
English: Ozempic should not be administered intravenously or intramuscularly.
Croatian: Ozempic se ne smije primjenjivati intravenski ili intramuskularno.
English: • it is more than 5 days since you should have used Ozempic, skip the missed dose.
Croatian: • prošlo je više od 5 dana od vremena kad ste trebali primijeniti lijek Ozempic, preskočite propuštenu dozu.
English: Ozempic can be administered with needles up to a length of 8 mm.
Croatian: Ozempic se smije primjenjivati s iglama duljine do 8 mm.
English: Keep away from the cooling element.
Croatian: Držati dalje od odjeljka za zamrzavanje.
English: Consistent with the potentially immunogenic properties of medicinal products containing proteins or peptides, patients may develop antibodies following treatment with semaglutide.
Croatian: Sukladno mogućim imunogenim svojstvima lijekova koji sadrže proteine ili peptide, u bolesnika se tijekom liječenja semaglutidom mogu razviti protutijela na semaglutid.
English: The total numbers of cardiovascular deaths, non-fatal myocardial infarctions and non-fatal strokes were 90, 111, and 71, respectively, including 44 (2.7%), 47 (2.9%), and 27 (1.6%), respectively, with semaglutide (figure 4).
Croatian: Ukupni broj smrti uzrokovanih kardiovaskularnim događajem, infarkta miokarda bez smrtnog ishoda i moždanih udara bez smrtnog ishoda bio je 90, 111, odnosno 71, uključujući 44 (2,7%), 47 (2,9%), odnosno 27 (1,6%) uz semaglutid (slika 4).
English: Semaglutide exposure increased in a dose proportional manner for doses of 0.5 mg and 1 mg.
Croatian: Izloženost semaglutidu povećala se proporcionalno dozi za doze od 0,5 mg i 1 mg.
English: Always make sure that a drop appears at the needle tip before you use a new pen for the first time.
Croatian: Uvijek provjerite da se kapljica pojavila na vrhu igle ako prvi put upotrebljavate novu brizgalicu.
English: • Unscrew the needle and dispose of it carefully in accordance with local guidelines.
Croatian: • Odvijte iglu i pažljivo je odložite u otpad sukladno lokalnim propisima.
English: Semaglutide compared to placebo lowered the energy intake of 3 consecutive ad libitum meals by 18-35%.
Croatian: Semaglutid u usporedbi s placebom snizio je unos energije 3 uzastopna ad libitum obroka za 18-35%.
English: In general, these reactions were mild or moderate in severity and of short duration.
Croatian: Općenito su te reakcije bile blage do umjerene težine i kratkog trajanja.
English: Semaglutide acts as a GLP-1 receptor agonist that selectively binds to and activates the GLP-1 receptor, the target for native GLP-1.
Croatian: Semaglutid djeluje kao agonist GLP-1 receptora koji se selektivno veže i aktivira GLP-1 receptor, ciljno mjesto nativnog GLP-1.
English: Figure 4 Forest plot: analyses of time to first occurrence of the composite outcome, its components and all cause death (SUSTAIN 6)
Croatian: Slika 4 Grafikon raspona pouzdanosti (engl. forest plot): analiza vremena do prve pojave kompozitnog ishoda, njegovih sastavnica i smrti zbog bilo kojeg uzroka (SUSTAIN 6)
English: Therapeutic experience in patients ≥75 years of age is limited (see section 5.2).
Croatian: ≥75 godina je ograničeno (vidjeti dio 5.2).
English: Semaglutide 0.25 mg is not a maintenance dose.
Croatian: Semaglutid od 0,25 mg nije doza održavanja.
English: Do not use this medicine if you notice that the solution is not clear and colourless or almost colourless.
Croatian: Ovaj lijek se ne smije upotrijebiti ako primijetite da otopina nije bistra i bezbojna ili gotovo bezbojna.
English: The efficacy and safety of Ozempic 0.5 mg and 1 mg once weekly were evaluated in six randomised controlled phase 3a trials that included 7,215 patients with type 2 diabetes mellitus (4,107 treated with semaglutide).
Croatian: Djelotvornost i sigurnost lijeka Ozempic 0,5 mg i 1 mg jedanput na tjedan procjenjivani su u šest randomiziranih ispitivanja faze 3a koja su uključivala 7215 bolesnika sa šećernom bolešću tipa 2 (4107 liječenih semaglutidom).
English: During induced hypoglycaemia, semaglutide compared to placebo did not alter the counter regulatory responses of increased glucagon and did not impair the decrease of C-peptide in patients with type 2-diabetes.
Croatian: Tijekom inducirane hipoglikemije semaglutid u usporedbi s placebom nije promijenio kontraregulatorne odgovore povećanog glukagona i nije narušio smanjenje C-peptida u bolesnika sa šećernom bolešću tipa 2.
English: Treatment with semaglutide demonstrated sustained, statistically superior and clinically meaningful reductions in HbA1c and body weight for up to 2 years compared to placebo and active control treatment (sitagliptin, insulin glargine, exenatide ER and dulaglutide).
Croatian: Liječenje semaglutidom pokazalo je održana, statistički superiorna i klinički značajna smanjenja HbA1c i tjelesne težine do 2 godine u usporedbi s placebom i aktivnim kontrolnim liječenjem (sitagliptin, glargin inzulin, eksenatid ER i dulaglutid).
English: A 2-year clinical trial investigated 3,297 patients with type 2 diabetes, with high cardiovascular risk, long duration of diabetes and poorly controlled blood glucose.
Croatian: U dvogodišnjem kliničkom ispitivanju sudjelovalo je 3297 bolesnika sa šećernom bolešću tipa 2 s visokim kardiovaskularnim rizikom, dugotrajnom šećernom bolešću i slabom regulacijom glukoze u krvi.
English: When Ozempic is added to existing metformin and/or thiazolidinedione therapy, the current dose of metformin and/or thiazolidinedione can be continued unchanged.
Croatian: Kad se Ozempic dodaje već postojećem liječenju metforminom i/ili tiazolidindionom, postojeća doza metformina i/ili tiazolidindiona može se nastaviti primjenjivati bez promjene.
English: There were 61% males, the mean age was 65 years and mean BMI was 33 kg/m2.
Croatian: 61% ispitanika bili su muškarci, srednja dob bila je 65 godina, a srednji ITM 33 kg/m2.
English: In foetuses, major skeletal and visceral malformations were observed, including effects on long bones, ribs, vertebrae, tail, blood vessels and brain ventricles.
Croatian: U fetusa su zabilježene velike koštane i visceralne malformacije, uključujući učinke na duge kosti, rebra, kralježnicu, rep, krvne žile i moždane komore.
English: Gastro-oesophageal reflux disease Eructation Flatulence
Croatian: Gastroezofagealna refluksna bolest Eruktacija Flatulencija
English: Frequent blood testing to determine the ability of your blood to clot may be required.
Croatian: Možda će biti potrebne učestale pretrage krvi kako bi se odredila sposobnost zgrušavanja krvi.
English: Dose selector Dose button
Croatian: Izbornik doze Gumb za doziranje
English: Systematic evaluation of diabetic retinopathy complication was only performed in the cardiovascular outcomes trial.
Croatian: Sistemska procjena komplikacije dijabetičke retinopatije provedena je jedino u ispitivanju kardiovaskularnih ishoda.
English: After first use: Store below 30°C or in a refrigerator (2°C to 8°C).
Croatian: Nakon prve primjene: Čuvati na temperaturi ispod 30°C ili u hladnjaku (2°C do 8°C).
English: Semaglutide should not be used in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.
Croatian: Semaglutid se ne smije primjenjivati u bolesnika sa šećernom bolešću tipa 1 niti za liječenje dijabetičke ketoacidoze.
English: Dose counter stopped: 1 mg left
Croatian: Brojčanik doze je zaustavljen: preostao 1mg
English: If a patient wishes to become pregnant, or pregnancy occurs, semaglutide should be discontinued.
Croatian: Ako bolesnica planira trudnoću ili zatrudni, liječenje semaglutidom treba prekinuti.
English: Difference from dulaglutide [95% CI]
Croatian: Razlika u odnosu na dulaglutid [95% CI]
English: Get help from a person with good eyesight who is trained to use the Ozempic pre-filled pen.
Croatian: Zatražite pomoć osobe koja dobro vidi i koja je naučila kako koristiti Ozempic napunjenu brizgalicu.
English: If there is still no drop, change the needle and repeat step 2 ‘Check the flow' once more.
Croatian: Ako se kapljica i dalje ne pojavi, promijenite iglu i još jednom ponovite 2. korak „Provjera protoka“.
English: Mechanistic evaluations indicated that the embryotoxicity involved a GLP-1 receptor mediated impairment of the nutrient supply to the embryo across the rat yolk sac.
Croatian: Mehanističke procjene pokazale su da je embriotoksičnost uključivala receptorom GLP-1 posredovano oštećenje opskrbe hranjivim tvarima za embrio putem žumanjčane vreće štakora.
English: The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.
Croatian: Mehanizam snižavanja glukoze u krvi također uključuje i blago odgođeno pražnjenje želuca u ranoj postprandijalnoj fazi.
English: If it shows 0.5, at least 0.5 mg is left in your pen.
Croatian: Ako pokazuje 0,5; to znači da je najmanje 0,5 mg preostalo u brizgalici.
English: Your pen is designed to be used with NovoFine and NovoTwist disposable needles up to a length of 8 mm.
Croatian: Vaša brizgalica je namijenjena za uporabu s jednokratnim iglama NovoFine ili NovoTwist duljine do 8 mm.
English: Inject your dose
Croatian: 4. Injicirajte svoju dozu
English: Semaglutide lowered fasting glucose after the first dose.
Croatian: Semaglutid je snizio glukozu natašte nakon prve doze.
English: Few episodes (0.1% of subjects, 0.001 events/patient year) were observed with semaglutide in combination with oral antidiabetics other than sulfonylureas.
Croatian: Nekoliko epizoda (0,1% ispitanika, 0,001 događaja/bolesnik-godini) zabilježeno je kad se semaglutid primjenjivao u kombinaciji s drugim oralnim antidijabeticima osim sulfonilureje.
English: Use of GLP-1 receptor agonists may be associated with gastrointestinal adverse reactions.
Croatian: Primjena agonista receptora GLP-1 može se povezati s gastrointestinalnim nuspojavama.
English: In lactating rats, semaglutide was excreted in milk.
Croatian: U štakora u laktaciji semaglutid se izlučivao u mlijeko.
English: The principal mechanism of protraction is albumin binding, which results in decreased renal clearance and protection from metabolic degradation.
Croatian: Glavni je mehanizam prolongacije vezanje albumina, što rezultira smanjenim bubrežnim klirensom i zaštitom od metaboličke razgradnje.
English: However, a direct effect of semaglutide on the foetus cannot be excluded.
Croatian: Međutim, direktan učinak semaglutida na fetus ne može se isključiti.
English: Do not use this medicine if you are breast-feeding, as it is unknown if it passes into breast milk.
Croatian: Nemojte primjenjivati ovaj lijek ako dojite jer nije poznato izlučuje li se u majčino mlijeko.
English: In clinical trials up to 1 year involving 4,807 patients with type 2 diabetes, adverse events related to diabetic retinopathy were reported in similar proportions of subjects treated with semaglutide (1.7%) and comparators (2.0%).
Croatian: U kliničkim ispitivanjima u trajanju do 1 godine u kojima je sudjelovalo 4807 bolesnika sa šećernom bolešću tipa 2, nuspojave povezane s dijabetičkom retinopatijom prijavljene su u sličnim omjerima ispitanika liječenih semaglutidom (1,7%) i lijekovima za usporedbu (2,0%).
English: Semaglutide reduces body weight and body fat mass through lowered energy intake, involving an overall reduced appetite.
Croatian: Semaglutid smanjuje tjelesnu težinu i količinu masnog tkiva sniženjem unosa energije koji obuhvaća općenito smanjeni apetit.
English: In female rats, an increase in oestrous length and a small reduction in number of ovulations were observed at doses associated with maternal body weight loss (see section 5.3).
Croatian: U ženki štakora zabilježeno je povećanje duljine estrusa i malo smanjenje broja ovulacija pri dozama povezanim s gubitkom tjelesne težine majke (vidjeti dio 5.3).
English: Body weight has an effect on the exposure of semaglutide.
Croatian: Tjelesna težina ima učinak na izloženost semaglutidu.
English: Patients with low body weight may experience more gastrointestinal side effects when treated with semaglutide.
Croatian: Bolesnici male tjelesne težine mogu imati više gastrointestinalnih nuspojava uz liječenje semaglutidom.
English: The most commonly reported adverse reaction was nausea.
Croatian: Najčešća prijavljena nuspojava bila je mučnina.
English: These other medicines may include: oral antidiabetics (such as metformin, thiazolidinediones, sulfonylureas) or insulin.
Croatian: Ti drugi lijekovi mogu obuhvaćati: oralne antidijabetike (primjerice, metformin, tiazolidindion, sulfonilureja) ili inzulin.
English: Always remove the needle from your pen immediately after each injection.
Croatian: Uvijek skinite iglu s brizgalice odmah nakon svakog injiciranja.
English: • Your doctor may increase your dose to 1 mg once a week if your blood sugar is not controlled well enough with a dose of 0.5 mg once a week.
Croatian: • Liječnik Vam može povećati dozu na 1 mg jedanput na tjedan ako se uz dozu od 0,5 mg jedanput na tjedan nije postigla odgovarajuća regulacija šećera u krvi.
English: The efficacy of semaglutide was not impacted by age, gender, race, ethnicity, BMI at baseline, body weight (kg) at baseline, diabetes duration and level of renal function impairment.
Croatian: Na djelotvornost semaglutida nije utjecala dob, spol, rasa, etničko porijeklo, ITM na početku, tjelesna težina (kg) na početku, trajanje šećerne bolesti ni razina oštećenja bubrežne funkcije.
English: Treat your pen with care.
Croatian: Pažljivo postupajte s brizgalicom.
English: How to identify a blocked or damaged needle - If 0 does not appear in the dose counter after continuously pressing the dose button, you may have used a blocked or damaged needle.
Croatian: - Ako se na brojčaniku doze ne prikaže 0 nakon neprestanog pritiskanja gumba za doziranje, možda ste koristili začepljenu ili oštećenu iglu.
English: • The starting dose is 0.25 mg once a week for four weeks.
Croatian: • Početna doza je 0,25 mg jedanput na tjedan tijekom četiri tjedna.
English: It is important that you continue with your diet and exercise plan as told by your doctor, pharmacist or nurse.
Croatian: Važno je nastaviti se pridržavati plana prehrane i vježbanja prema uputama liječnika, ljekarnika ili medicinske sestre.
English: The proportion of patients tested positive for anti-semaglutide antibodies at any time point post-baseline was low (1−2%) and no patients had anti-semaglutide neutralising antibodies or anti-semaglutide antibodies with endogenous GLP-1 neutralising effect at end-of-trial.
Croatian: Udio bolesnika koji su bili pozitivni na protutijela na semaglutid u bilo kojem trenutku nakon početka ispitivanja bio je nizak (1-2%) i ni u jednog bolesnika nisu se razvila neutralizacijska protutijela na semaglutid ni protutijela na semaglutid s neutralizacijskim učinkom na endogeni GLP-1 na kraju ispitivanja.