FrancophonIA/ELRC3.0 huggingface dataset:
English: Reported symptoms of overdose include neutropenia, anaemia, thrombocytopenia, mucositis, sensory polyneuropathy, and rash.
Danish: De rapporterede symptomer ved overdosering omfatter neutropeni, anæmi, trombocytopeni, mucositis, sensorisk polyneuropati og udslæt.
English: If you are breast-feeding, tell your doctor.
Danish: Hvis De ammer, skal De fortælle Deres læge dette.
English: Concomitant yellow fever vaccine (see section 4.5).
Danish: Samtidig brug af vaccination mod gul feber (se pkt.
English: A statistically significant improvement of the clinically relevant symptoms (pain and dyspnoea) associated with malignant pleural mesothelioma in the pemetrexed /cisplatin arm (212 patients) versus the cisplatin arm alone (218 patients) was demonstrated using the Lung Cancer Symptom Scale.
Danish: Ved hjælp af lungecancersymptomskalaen blev der påvist en statistisk signifikant bedring af de klinisk relevante symptomer (smerte og dyspnø) i forbindelse med malignt pleuramesoteliom i pemetrexed/cisplatin-armen (212 patienter) versus armen med cisplatin alene (218 patienter).
English: Grade 3 or 4 mucositis
Danish: Mucositis af grad 3 eller 4
English: Less toxicity and reduction in Grade 3/4 haematologic and non-haematologic toxicities, such as neutropenia, febrile neutropenia, and infection with Grade 3/4 neutropenia, were reported when pretreatment with folic acid and vitamin B12 was administered.
Danish: Der blev observeret en mindre toksicitet og en reduktion i antallet af hæmatologiske og ikkehæmatologiske toksiciteter af grad 3/4 såsom neutropeni, febril neutropeni og infektion med neutropeni af grad 3/4, når patienterne var i forbehandling med folsyre og B12-vitamin.
English: Children and adolescents There is no relevant use of pemetrexed in the paediatric population.
Danish: Børn og unge Det er ikke relevant at bruge pemetrexed til børn og unge.
English: Method of administration For Precautions to be taken before handling or administering Pemetrexed Pfizer, see section 6.6.
Danish: For information om sikkerhedsforanstaltninger, der skal tages før håndtering og administration af Pemetrexed Pfizer, se pkt.
English: The reconstituted solution is clear and ranges in colour from colourless to yellow or green-yellow without adversely affecting product quality.
Danish: Den rekonstituerede opløsning er klar og varierer i farve fra farveløs til gul eller grøngul, hvilket ikke påvirker produktets kvalitet.
English: Fast heart rate
Danish: Hurtig puls
English: Pemetrexed Pfizer must only be reconstituted with sterile water for injections.
Danish: Pemetrexed Pfizer må kun rekonstitueres med sterilt vand til injektionsvæsker.
English: 50% of previous dose
Danish: 50 % af tidligere dosis
English: This leaflet was last revised in month YYYY.
Danish: Denne indlægsseddel blev senest ændret { MM/ÅÅÅÅ }
English: The recommended dose of cisplatin is 75 mg/m2 BSA infused over two hours approximately 30 minutes after completion of the pemetrexed infusion on the first day of each 21-day cycle.
Danish: Den anbefalede dosis cisplatin er 75 mg/m2 legemsoverflade infunderet over 2 timer cirka 30 minutter efter afsluttet infusion af pemetrexed på den første dag i hver 21-dages-serie.
English: Efficacy of pemetrexed + cisplatin vs. gemcitabine + cisplatin in first-line non-small cell lung cancer - ITT population and histology subgroups
Danish: Effekt af pemetrexed + cisplatin mod gemcitabin + cisplatin ved 1. linje-behandling af ikkesmåcellet lungecancer - ITTpopulation og histologiske undergrupper.
English: Hypernatraemia - increased sodium in blood Inflammation of the skin, mainly of the lower limb with swelling, pain and redness
Danish: Øget koncentration af natrium i blodet (hypernatriæmi) Betændelse i huden, hovedsagligt i underbenet med hævelse, smerte og rødme.
English: Adenocarcinom a (N = 847)
Danish: Adenocarcinom (N = 847)
English: Common Vomiting Mucositis/
Danish: Almindelig Opkastning Mucositis/stomatitis
English: The percentage of patients that received post-study treatment was 64.3% for pemetrexed and 71.7% for placebo.
Danish: 64,3 % af pemetrexedpatienterne og 71,7 % af placebopatienterne fik behandling efter studiet.
English: There were no clinically relevant differences observed for the safety profile of pemetrexed within the histology subgroups.
Danish: Der blev ikke set nogen klinisk relevante forskelle i sikkerhedsprofilen for pemetrexed inden for de histologiske undergrupper.
English: Pemetrexed at a dose of 500 mg/m2 was studied as a single agent in 64 chemonaive patients with malignant pleural mesothelioma.
Danish: Pemetrexed i en dosis på 500 mg/m2 blev undersøgt som enkeltstof- behandling til 64 patienter med malignt pleuramesoteliom, som ikke tidligere havde modtaget kemoterapi.
English: In patients with normal renal function (creatinine clearance ≥ 80 ml/min), high doses of non-steroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen > 1600 mg/day) and acetylsalicylic acid at higher doses (≥ 1.3 g daily) may decrease pemetrexed elimination and, consequently, increase the occurrence of pemetrexed adverse events.
Danish: Hos patienter med en normal nyrefunktion (kreatininclearance ≥ 80 ml/min) kan høje doser af nonsteroide anti-inflammatoriske lægemidler (NSAID-præparater såsom ibuprofen > 1600 mg/dag) og acetylsalicylsyre i høje doser (≥ 1,3 g daglig) nedsætte udskillelsen af pemetrexed, og dermed øge forekomsten af bivirkninger relateret til pemetrexed.
English: Sepsis, sometimes fatal, has been commonly reported during clinical trials with pemetrexed.
Danish: Sepsis, sommetider dødelig, blev rapporteret med frekvensen "almindelig" under kliniske studier med pemetrexed.
English: Serious cardiovascular and cerebrovascular events, including myocardial infarction, angina pectoris, cerebrovascular accident, and transient ischaemic attack, have been uncommonly reported during clinical studies with pemetrexed, usually when given in combination with another cytotoxic agent.
Danish: Alvorlige kardiovaskulære og cerebrovaskulære bivirkninger, herunder myokardieinfarkt, angina pectoris, cerebrovaskulære hændelser og forbigående iskæmisk anfald er ikke almindeligt rapporteret under kliniske studier med pemetrexed, sædvanligvis når pemetrexed gives i kombination med et andet cytotoksisk lægemiddelstof.
English: If particulate matter is observed, do not administer.
Danish: Hvis der observeres partikler, må opløsningen ikke indgives.
English: Type I glass vial with bromobutyl rubber stopper containing 100 mg, 500 mg or 1,000 mg of pemetrexed
Danish: Hætteglas af type I med bromobutylgummiprop, der indeholder 100 mg, 500 mg eller 1.000 mg pemetrexed
English: Oesophagitis/ radiation oesophagitis has been uncommonly reported during clinical trials with pemetrexed.
Danish: Øsophagitis/ strålings-øsophagitis er ikke almindeligt rapporteret under kliniske studier med pemetrexed.
English: What you need to know before you use Pemetrexed Pfizer
Danish: Det skal de vide, før De begynder at bruge Pemetrexed Pfizer
English: Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Danish: Inden for hver gruppe af bivirkninger med samme frekvens er bivirkningerne opstillet efter, hvor alvorlige de er.
English: Other (N = 252)
Danish: Andre (N = 252)
English: Mesothelioma
Danish: Mesoteliom:
English: There were no clinically relevant differences observed for the safety profile of pemetrexed plus cisplatin within the histology subgroups.
Danish: Der blev ikke set klinisk relevante forskelle i sikkerhedsprofilen for pemetrexed plus cisplatin inden for de histologiske undergrupper.
English: Patients also required lower administration of erythropoietin/darbopoietin (10.4% versus 18.1%, p < 0.001), G-CSF/GM-CSF (3.1% versus 6.1%, p = 0.004), and iron preparations (4.3% versus 7.0%, p = 0.021).
Danish: Patienterne behøvede ligeledes mindre erythropoietin/darbopoietin (10,4 % mod 18,1 %, p < 0,001), G-CSF/GM-CSF (3,1 % mod 6,1 %; p = 0,004) og midler med jern (4,3 % mod 7,0 %; p = 0,021).
English: Patients should be monitored for myelosuppression during therapy and pemetrexed should not be given to patients until absolute neutrophil count (ANC) returns to ≥ 1,500 cells/mm3 and platelet count returns to ≥ 100,000 cells/mm3.
Danish: Under behandlingen skal patienten monitoreres for myelosuppression, og pemetrexed må ikke gives til patienter, før det absolutte neutrofiltal (ANC) igen er ≥ 1.500 celler/mm
English: Radiation recall (a skin rash like severe sunburn) which can occur on skin that has previously been exposed to radiotherapy, from days to years after the radiation.
Danish: Sjælden (kan forekomme hos op til 1 ud af 1.000 personer) Radiation recall (et hududslæt, der ligner en alvorlig solskoldning), som kan opstå på hud, der tidligere har været udsat for strålebehandling, dage eller op til år efter strålebehandlingen.
English: Nephrogenic diabetes insipidus and renal tubular necrosis were also reported in post marketing setting with pemetrexed alone or with other chemotherapeutic agents.
Danish: Nefrogen diabetes insipidus og renal tubulær nekrose blev også indberettet efter markedsføring af lægemidlet både med pemetrexed alene og i kombination med andre cystostatika.
English: Pemetrexed is physically incompatible with diluents containing calcium, including lactated Ringer's injection and Ringer's injection.
Danish: Pemetrexed er fysisk inkompatibelt med opløsningsvæsker, der indeholder calcium, herunder lakteret Ringer's opløsning og Ringer's opløsning.
English: Abbreviations: CI = confidence interval; HR = hazard ratio; ITT = intent-to-treat; N = total population size.
Danish: Responsrate (%) (95 %-CI) Stabil sygdom (%) Forkortelser: CI = konfidensinterval; HR = hazard ratio; ITT = intent to treat; N = samlet populationsstørrelse.
English: In clinical trials, cases of colitis (including intestinal and rectal bleeding, sometimes fatal, intestinal perforation, intestinal necrosis and typhlitis) have been reported uncommonly in patients treated with pemetrexed.
Danish: Tilfælde af colitis (inklusive intestinal og rektal blødning, sommetider dødelig, intestinal nekrose og typhliitis) er ikke almindeligt rapporteret hos patienter behandlet med pemetrexed i kliniske studier.
English: NSCLC, first-line treatment
Danish: NSCLC, 1. linje-behandling
English: Liver: abnormal blood tests
Danish: Lever: abnorme blodprøveresultater Rindende øjne
English: The most commonly reported undesirable effects related to pemetrexed, whether used as monotherapy or in combination, are bone marrow suppression manifested as anaemia, neutropenia, leucopenia, thrombocytopenia; and gastrointestinal toxicities, manifested as anorexia, nausea, vomiting, diarrhoea, constipation, pharyngitis, mucositis, and stomatitis.
Danish: De hyppigst indberettede bivirkninger relateret til pemetrexed ved både monoterapi og kombinationsbehandling, er knoglemarvssuppression med anæmi, neutropeni, leukopeni, trombocytopeni samt gastrointestinal toksicitet med anoreksi, kvalme, opkastning, diaré, forstoppelse, pharyngitis, mucositis og stomatitis.
English: **Refer to NCI CTCAE Criteria (Version 3.0; NCI 2003) for each grade of toxicity.
Danish: ** Se NCI CTCAE Criteria (Version 3.0; NCI 2003) for hver toksicitetsgrad De viste indberetningsfrekvenser er i henhold til CTCAE version 3.0.
English: Pancytopenia has been uncommonly reported during clinical trials with pemetrexed.
Danish: Pancytopeni er sjældent rapporteret under kliniske studier med pemetrexed.
English: Patients treated with pemetrexed and cisplatin required fewer transfusions (16.4% versus 28.9%, p < 0.001), red blood cell transfusions (16.1% versus 27.3%, p < 0.001) and platelet transfusions (1.8% versus 4.5%, p =0.002).
Danish: Patienter, der blev behandlet med pemetrexed og cisplatin, havde brug for færre transfusioner (16,4 % mod 28,9 %; p <0,001), transfusioner af røde blodlegemer (16,1 % mod 27,3 %; p <0,001) og blodpladetransfusioner (1,8 % mod 4,5 %; p = 0,002).
English: Colitis (inflammation of the lining of the large bowel, which may be accompanied by intestinal or rectal bleeding)
Danish: Tyktarmsbetændelse (betændelse i tyktarmen, som kan ledsages af blødning fra tarm eller endetarm).
English: In patients treated for non-small cell lung cancer after prior chemotherapy, the recommended dose of pemetrexed is 500 mg/m2 BSA administered as an intravenous infusion over 10 minutes on the first day of each 21-day cycle.
Danish: Til patienter, der behandles for ikke-småcellet lungecancer efter tidligere behandling med kemoterapi, er den anbefalede dosis af pemetrexed 500 mg/m2 legemesoverflade indgivet som intravenøs infusion over 10 minutter på den første dag i hver 21-dages-serie.
English: All grades toxicity
Danish: Toksicitet i alle grader
English: Pemetrexed can suppress bone marrow function as manifested by neutropenia, thrombocytopenia, and anaemia (or pancytopenia) (see section 4.8).
Danish: Pemetrexed kan hæmme knoglemarvsfunktionen, hvilket kan ytre sig som neutropeni, trombocytopeni og anæmi (eller pancytopeni) (se pkt.
English: gemcitabine/cisplatin (N = 830)
Danish: gemcitabin/ cisplatin (N = 830)
English: Cases of radiation pneumonitis have been reported in patients treated with radiation either prior, during, or subsequent to their pemetrexed therapy.
Danish: Der er rapporteret om tilfælde af strålingspneumonitis hos patienter, som fik strålebehandling enten før, under eller efter behandling med pemetrexed.
English: Bullous conditions (blistering skin diseases)-including Stevens-Johnson syndrome and toxic epidermal necrolysis
Danish: Bulløse tilstande (hudsygdomme med blæredannelser), inklusive Stevens-Johnsons syndrom og toksisk epidermal nekrolyse.
English: Anticipated complications of overdose include bone marrow suppression as manifested by neutropenia, thrombocytopenia, and anaemia.
Danish: De forventede komplikationer ved overdosering omfatter knoglemarvshæmning, som ytrer sig ved neutropeni, trombocytopeni og anæmi.
English: • Allergic reaction: if you develop skin rash (very common) / burning or prickling sensation (common), or fever (common).
Danish: Allergisk reaktion: Hvis De udvikler udslæt (meget almindelig)/en brændende eller prikkendefornemmelse(almindelig)ellerfeber (almindelig).Hudreaktionerkanisjældne tilfældeværealvorligeogkanmedføredøden.
English: NSCLC, maintenance treatment JMEN
Danish: NSCLC, vedligeholdelsesbehandling
English: Malignant pleural mesothelioma
Danish: Malignt pleuramesoteliom
English: Dose modification table for pemetrexed (as a single agent or in combination) and cisplatin - Non-haematologic toxicities a, b
Danish: Tabel 2 - Dosisjustering for pemetrexed (som et enkeltstof eller i kombination) og cisplatinikke-hæmatologiske toksiciteter a, b ikke-hæmatologisk toksicitet a, b
English: The use of calcium folinate/folinic acid in the management of pemetrexed overdose should be considered.
Danish: Til afhjælpning af en overdosering af pemetrexed bør det overvejes at anvende kalciumfolinat/folsyre.
English: The analysis of the impact of NSCLC histology on overall survival demonstrated clinically relevant differences in survival according to histology, see table below.
Danish: Analysenafindvirkningenpå NSCLC-histologienfortotaloverlevelsevistekliniskrelevante forskelleioverlevelsebaseretpå histologi,se nedenstående tabel.
English: Patients with renal impairment (Standard Cockcroft and Gault formula or glomerular filtration rate measured Tc99m DPTA serum clearance method)
Danish: Patienter med nedsat nyrefunktion (standardformel, der er udviklet af Cockcroft og Gault, eller glomerulær filtrationshastighed baseret på Tc99m-DPTA-serum-clearancemetoden) Pemetrexed udskilles primært uforandret via nyrerne.
English: Rarely seen events include Stevens-Johnson syndrome and toxic epidermal necrolysis.
Danish: Sjældne bivirkninger omfatter Stevens-Johnsons syndrom og toksisk epidermal nekrolyse.
English: Pemetrexed has a steady-state volume of distribution of
Danish: Pemetrexed har et steady state-fordelingsvolumen på 9 l/m2.
English: The pharmacokinetic properties of pemetrexed are not influenced by concurrently administered cisplatin.
Danish: De farmakokinetiske egenskaber for pemetrexed påvirkes ikke af samtidig indgivelse af cisplatin.
English: Pemetrexed infusion solutions prepared as directed above are compatible with polyvinyl chloride and polyolefin- lined administration sets and infusion bags.
Danish: Pemetrexedinfusionsopløsninger, der er forberedt som angivet ovenfor, er kompatible med indgivelsessæt og dropposer belagt med polyvinylchlorid og polyolefin.
English: Women must use effective contraception during treatment with pemetrexed.
Danish: Kvinder skal anvende effektive svangerskabsforebyggende midler under behandlingen med pemetrexed.
English: The table below provides the frequency and severity of undesirable effects that have been reported in >5% of 168 patients with mesothelioma who were randomised to receive cisplatin and pemetrexed, and 163 patients with mesothelioma randomised to receive single-agent cisplatin.
Danish: Nedenstående tabel viser hyppigheden og sværhedsgraden af bivirkninger, der blev rapporteret hos > 5 % af 168 patienter med mesoteliom, som var randomiseret til behandling med cisplatin og pemetrexed, og 163 patienter med mesoteliom, som var randomiseret til enkeltstofbehandling med cisplatin.
English: Time to treatment failure (TTTF - months)
Danish: Tid til behandlingssvigt (TTTF - måneder) (N = 283)
English: Uncommon cases of acute renal failure have been reported with pemetrexed alone or in association with other chemotherapeutic agents (see section 4.4).
Danish: Ikke almindelige tilfælde af akut nyresvigt er rapporteret ved brug af pemetrexed alene og i kombinationsbehandling med andre cytostatika (se pkt.
English: Warnings and precautions Talk to your doctor or hospital pharmacist before receiving Pemetrexed Pfizer.
Danish: Kontakt lægen eller sundhedspersonalet, før De får Pemetrexed Pfizer.
English: Pemetrexed Pfizer is given in combination with cisplatin, another anti-cancer medicine, as treatment for malignant pleural mesothelioma, a form of cancer that affects the lining of the lung, to patients who have not received prior chemotherapy.
Danish: Pemetrexed Pfizer anvendes sammen med cisplatin, en anden medicin mod kræft, til behandling af malignt pleuramesoteliom, en kræftform som påvirker lungehinderne, til patienter, som ikke tidligere har fået kemoterapi.
English: • 95% CI for HR
Danish: 95 %-CIformedianen HR
English: Stomatitis/Pharyngitis Diarrhoea without colostomy
Danish: Diarré uden kolostomi
English: The table below provides the frequency and severity of undesirable effects considered possibly related to study medicinal product that have been reported in > 5% of 839 patients with NSCLC who were randomised to receive cisplatin and pemetrexed and 830 patients with NSCLC who were randomised to receive cisplatin and gemcitabine.
Danish: Nedenstående tabel viser hyppigheden og sværhedsgraden af bivirkninger, der blev vurderet som muligt relateret til forsøgsmedicinen, og som blev rapporteret hos > 5 % af de 839 patienter med NSCLC, der blev randomiseret til at få cisplatin og pemetrexed, samt de 830 patienter med NSCLC, som blev randomiseret til at få cisplatin og gemcitabin.
English: Rash/ desquamation Common Pruritus Alopecia
Danish: Almindelig Pruritus Alopeci
English: During the study, low-dose folic acid and vitamin B12 supplementation was introduced to patients' therapy to reduce toxicity.
Danish: I løbet af studiet blev patienternes behandling suppleret med et lavdosistilskud af folsyre og B12vitamin for at mindske toksiciteten.
English: A multi-centre, randomised, open-label, Phase-3 study of pemetrexed plus cisplatin versus gemcitabine plus cisplatin in chemonaive patients with locally advanced or metastatic (Stage IIIb or IV) non-small cell lung cancer (NSCLC) showed that pemetrexed plus cisplatin (Intent-To-Treat [ITT] population N = 862) met its primary endpoint and showed similar clinical efficacy as gemcitabine plus cisplatin (ITT N = 863) in overall survival (HR 0.94; 95% CI= 0.84-1.05).
Danish: Et randomiseret, åbent, fase 3-multicenterstudie af pemetrexed plus cisplatin versus gemcitabin plus cisplatin med patienter, der ikke tidligere har fået kemoterapi, med lokalt fremskreden eller metastatisk (fase III b eller IV) ikke-småcellet lungecancer (NSCLC) viste, at pemetrexed plus cisplatin (intent-to-treat [ITT] population N=862) mødte dets primære endepunkt og viste lignende klinisk virkning som gemcitabin plus cisplatin (ITT N=863) på total overlevelse (HR 0,94; 95 %, CI = 0,84-1,05).
English: Efficacy parameter pemetrexed / cisplatin (N = 226)
Danish: Effektparameter pemetrexed/ cisplatin (N = 226)
English: PARAMOUNT: Kaplan-Meier plot of progression-free survival (PFS) and Overall Survival (OS) for continuation pemetrexed maintenance versus placebo in patients with NSCLC other than predominantly squamous cell histology (measured from randomisation)
Danish: PARAMOUNT: Kaplan-Meier-kurver for progressionsfri overlevelse (PFS) og total overlevelse (OS) for pemetrexed induktionsbehandling efterfulgt af pemetrexed vedligeholdelsesbehandling versus placebo hos patienter med NSCLC bortset fra cancer hovedsagelig bestående af pladeepitelceller (målt fra randomiseringen)
English: After reconstitution as directed, the solution contains 25 mg/ml of pemetrexed.
Danish: Efter rekonstitution indeholder opløsningen 25 mg/ml pemetrexed.
English: Grade 3-4 toxicity
Danish: Toksicitet i grad 3-4
English: Progression-free survival (PFS) and overall response rate were similar between treatment arms: median PFS was 4.8 months for pemetrexed plus cisplatin versus 5.1 months for gemcitabine plus cisplatin (adjusted hazard ratio (HR) 1.04; 95% CI= 0.94-1.15), and overall response rate was 30.6% (95% CI= 27.3- 33.9) for pemetrexed plus cisplatin versus 28.2% (95% CI= 25.0-31.4) for gemcitabine plus cisplatin.
Danish: Progressionsfrioverlevelse(PFS)ogstørrelsen afdettotale responsvarens mellemde to behandlingsarme:medianPFS var4,8 månederforpemetrexed plus cisplatinmod5,1 månederfor gemcitabinplus cisplatin (justerethazardratio1.04;95 %CI= 0,94-1,15)ogdettotale respons var 30,6 %(95 %CI= 27,3-33,9)forpemetrexed plus cisplatin mod28,2 %(95 %CI= 25,0-31,4)for gemcitabinplus cisplatin.
English: This suggests that pemetrexed may impair male fertility.
Danish: Dette tyder på, at pemetrexed kan nedsætte fertiliteten hos hanner.
English: Frequency* Event**
Danish: Hyppighed* Bivirkning**
English: General disorders and administration site conditions
Danish: Almene symptomer og symptomer på administrationsstedet
English: A multi-centre, randomised, open-label Phase-3 study of pemetrexed versus docetaxel in patients with locally advanced or metastatic NSCLC after prior chemotherapy has shown median survival times of 8.3 months for patients treated with pemetrexed (Intent-To-Treat [ITT] population N = 283) and 7.9 months for patients treated with docetaxel (ITT N = 288).
Danish: Et åbent, randomiseret fase 3-multicenterstudie med pemetrexed versus docetaxel til patienter med lokalt fremskreden eller metastatisk NSCLC (ikke-småcellet lungekræft), der tidligere var behandlet med kemoterapi, har vist en median overlevelsestid på 8,3 måneder for patienter, som blev behandlet med pemetrexed (intent-to-treat-population, N = 283), og 7,9 måneder for patienter, som blev behandlet med docetaxel (intent-to-treat, N = 288).
English: Therefore, the use of pemetrexed in patients with creatinine clearance of <45 ml/min is not recommended (see section 4.2).
Danish: Pemetrexed anbefales derfor ikke til patienter med en kreatininclearance på < 45 ml/min (se pkt.
English: If pemetrexed solutions contact the mucous membranes, flush thoroughly with water.
Danish: Hvis pemetrexedopløsning kommer i kontakt med slimhinderne, skal de skylles grundigt med vand.