FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients should be advised to seek medical advice if they experience joint aches and pain, joint stiffness or difficulty in movement.
Croatian: Bolesnicima treba preporučiti da potraže liječnički savjet ako osjete bolove ili ukočenost u zglobovima ili imaju otežano kretanje.
English: rare: hepatosplenomegaly, cholecystitis a
Croatian: rijetko: hepatosplenomegalija, kolecistitis a
English: Although this study presented some limitations (i.e., unbound drug concentrations not studied), results suggested that the atazanavir pharmacokinetic parameters were decreased by 30% to 50% in patients undergoing haemodialysis compared to patients with normal renal function.
Croatian: Iako je ovo ispitivanje imalo neka ograničenja (tj., nisu ispitane koncentracije nevezanog lijeka), rezultati ukazuju na to da su farmakokinetički parametri atazanavira bili smanjeni za 30% do 50% u bolesnika na hemodijalizi u usporedbi s bolesnicima s normalnom funkcijom bubrega.
English: Atazanavir is metabolised and eliminated primarily by the liver.
Croatian: Atazanavir se metabolizira i eliminira prvenstveno putem jetre.
English: FC susceptibility in cell culture relative to the wild-type reference was assayed using PhenoSense
Croatian: FC osjetljivosti u staničnoj kulturi u odnosu na referentni divlji tip ispitala se pomoću PhenoSense
English: • gait disturbance (abnormal manner of walking)
Croatian: • poremećaj hoda (abnormalan način hodanja)
English: If the use of atorvastatin is considered strictly necessary, the lowest possible dose of atorvastatin should be administered with careful safety monitoring (see section 4.4).
Croatian: Ako je uporaba atorvastatina neophodno potrebna, treba primijeniti najnižu moguću dozu atorvastatina uz poman nadzor sigurnosti primjene (vidjeti dio 4.4).
English: As a general rule, it is recommended that HIV infected women not breast-feed their infants in order to avoid transmission of HIV.
Croatian: Kao opće pravilo, preporučuje da žene zaražene HIV-om ne doje svoju dojenčad kako bi se izbjegao prijenos HIV-a.
English: Switching to capsules from other formulations is encouraged as soon as patients are able to consistently swallow capsules.
Croatian: Preporučuje se prelazak s drugih oblika na kapsule čim bolesnici mogu pouzdano progutati kapsule.
English: If available, 90% confidence intervals (CI) are shown in parentheses.
Croatian: Intervali pouzdanosti (CI) od 90% navedeni su u zagradi, ako su dostupni.
English: Treatment of overdose with atazanavir should consist of general supportive measures, including monitoring of vital signs and electrocardiogram (ECG), and observations of the patient's clinical status.
Croatian: Liječenje predoziranja atazanavirom treba se sastojati od općih potpornih mjera, uključujući praćenje vitalnih znakova i elektrokardiogram (EKG), te promatranja kliničkog stanja bolesnika.
English: Time-averaged difference ATV/RTV-LPV/RTV [97.5% CI
Croatian: Vremenski uprosječena razlika ATV/RTVLPV/RTV [97,5% CI
English: Atazanavir Mylan is an antiviral (or antiretroviral) medicine.
Croatian: Atazanavir Mylan je antivirusni (ili antiretrovirusni) lijek.
English: Since there are limited data available and due to inter-patient variability during pregnancy, Therapeutic Drug Monitoring (TDM) may be considered to ensure adequate exposure.
Croatian: Budući da su dostupni podaci ograničeni i da postoji varijabilnost između bolesnica tijekom trudnoće, može se razmotriti mogućnost praćenja koncentracije lijeka tijekom liječenja kako bi se osigurala odgovarajuća izloženost.
English: Two minor metabolites of atazanavir in plasma have been characterised.
Croatian: Opisana su dva manja metabolita atazanavira u plazmi.
English: Intent-to-treat analysis, with missing values considered as failures.
Croatian: Analiza prema planiranom liječenju, s time da su se vrijednosti koje su nedostajale smatrale neuspjehom.
English: Electrocardiographic changes (sinus bradycardia, prolongation of PR interval, prolongation of QT interval, and prolongation of QRS complex) were observed only in an initial 2 week oral toxicity study performed in dogs.
Croatian: Elektrokardiografske promjene (sinusna bradikardija, produljenje PR intervala, produljenje QT intervala i produljenje QRS kompleksa) bile su opažene samo u početnom dvotjednom ispitivanju oralne toksičnosti provedenom u pasa.
English: • medicines to lower blood pressure, to slow heart rate, or to correct heart rhythm (amiodarone,
Croatian: • lijekove za snižavanje krvnog tlaka, usporavanje rada srca ili ispravljanje srčanog ritma
English: Grade 3 or 4 elevation of total bilirubin was noted in 37% (6% Grade 4).
Croatian: Povišenje ukupnog bilirubina 3. ili 4. stupnja bilo je zabilježeno u 37% bolesnika (4. stupanj u 6%).
English: Pharmacokinetic Parameter
Croatian: Farmakokinetički parametar
English: The mean AUC(0-∞) was 42% greater in subjects with impaired hepatic function than in healthy subjects.
Croatian: Srednja vrijednost AUC(0-∞) bila je 42% veća u bolesnika s oštećenjem funkcije jetre nego u zdravih ispitanika.
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Croatian: Znakovi osteonekroze su ukočenost zglobova, bolovi (osobito u kuku, koljenu i ramenu) i otežano kretanje.
English: • that co-administration with famotidine is not recommended but if required, atazanavir without ritonavir should be administered either 2 hours after famotidine or 12 hours before.
Croatian: • Ne preporučuje se istovremena primjena s famotidinom, ali ako je ona neophodna, atazanavir bez ritonavira treba primijeniti ili 2 sata nakon famotidina ili 12 sati prije njega.
English: Other forms of this medicine may be available for use in children at least 3 months old and weighing at least 5 kg.
Croatian: Drugi oblici ovog lijeka mogu biti dostupni za primjenu u djece u dobi od najmanje 3 mjeseca i tjelesne težine od najmanje 5 kg.
English: Haemophiliac patients should therefore be made aware of the possibility of increased bleeding.
Croatian: Bolesnici s hemofilijom stoga trebaju biti svjesni povećane mogućnosti krvarenja.
English: Atazanavir Mylan capsules may be used by adults and children 6 years of age and older.
Croatian: Atazanavir Mylan kapsule mogu uzimati odrasli i djeca u dobi od 6 ili više godina.
English: UNIQUE IDENTIFIER - 2D BARCODE
Croatian: 17. JEDINSTVENI IDENTIFIKATOR- 2D BARKOD
English: Atazanavir Mylan with food and drink
Croatian: Atazanavir Mylan s hranom i pićem
English: ** Based on historical comparison.
Croatian: ** Na temelju usporedbe s podacima iz prethodnih ispitivanja.
English: Therefore, such co-administration is not recommended.
Croatian: Stoga se njihova istovremena primjena ne preporučuje.
English: The use of higher ritonavir doses may alter the safety profile of atazanavir (cardiac effects, hyperbilirubinaemia) and therefore is not recommended.
Croatian: Primjena viših doza ritonavira može promijeniti sigurnosni profil atazanavira (učinci na srce, hiperbilirubinemija) te se stoga ne preporučuje.
English: Number of patients evaluable.
Croatian: Broj bolesnika koje se moglo procijeniti.
English: If necessary, monitor lamotrigine concentrations and adjust the dose accordingly.
Croatian: Po potrebi treba nadzirati koncentracije lamotrigina i u skladu s time prilagoditi dozu.
English: The use of atazanavir in children less than 3 months of age and weighing less than 5 kg has not been studied due to the risk of serious complications.
Croatian: Primjena atazanavira u djece mlađe od 3 mjeseca i tjelesne težine manje od 5 kg nije ispitana zbog rizika od pojave ozbiljnih komplikacija.
English: Following a single 400 mg dose of
Croatian: Nakon jednokratne doze od 400-mg
English: Desacetyl-diltiazem AUC ↑165%
Croatian: Dezacetil-diltiazem AUC ↑165%
English: When transitioning between formulations, a change in dose may be needed.
Croatian: Kada se prelazi s jednog oblika na drugi, možda će biti potrebna promjena doze.
English: Calcium channel blockers Bepridil
Croatian: Blokatori kalcijskih kanala Bepridil
English: A population pharmacokinetic analysis of samples from Phase II clinical trials indicated no effect of race on the pharmacokinetics of atazanavir.
Croatian: Analiza populacijske farmakokinetike uzoraka iz kliničkih ispitivanja faze II pokazala je da rasa ne utječe na farmakokinetiku atazanavira.
English: Your doctor has prescribed Atazanavir Mylan for you because you are infected by the HIV that causes Acquired Immunodeficiency Syndrome (AIDS).
Croatian: Liječnik Vam je propisao Atazanavir Mylan zato što ste zaraženi HIV-om koji uzrokuje sindrom stečene imunodeficijencije (SIDA).
English: Some patients taking combination antiretroviral therapy may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Croatian: Neki bolesnici koji uzimaju kombiniranu antiretrovirusnu terapiju mogu razviti bolest kostiju koja se zove osteonekroza (odumiranje koštanog tkiva zbog gubitka opskrbe krvlju).
English: When given with atazanavir, the recommended dose of rifabutin is 150 mg 3 times per week on set days (for example MondayWednesday-Friday).
Croatian: Kad se daje s atazanavirom, preporučena doza rifabutina je 150 mg tri puta tjedno u određene dane (na primjer, ponedjeljaksrijeda-petak).
English: If you notice a change in the way your heart beats (heart rhythm changes), please inform your doctor.
Croatian: Ako primijetite promjenu u radu srca (promjene srčanog ritma), obavijestite o tome svog liječnika.
English: No single dose of famotidine should exceed 20 mg, and the total daily dose of famotidine should not exceed 40 mg.
Croatian: Nijedna pojedinačna doza famotidina ne smije biti veća od 20 mg, a ukupna dnevna doza famotidina ne smije biti veća od 40 mg.
English: Atazanavir Mylan should not be used in children less than 3 months because of safety concerns especially taking into account the potential risk of kernicterus.
Croatian: Atazanavir Mylan se ne smije primijenjivati u djece mlađe od 3 mjeseca zbog sigurnosnih razloga, osobito kada se uzme u obzir mogući rizik od kernikterusa.
English: Table 7: Efficacy Outcomes (paediatric patients 6 years to less than 18 years of age) at Week 48 (Study AI424-020) Parameter
Croatian: Tablica 7: Ishodi djelotvornosti (pedijatrijski bolesnici u dobi od 6 godina do manje od 18 godina) u 48. tjednu (Ispitivanje AI424-020)
English: Neither metabolite demonstrated in vitro antiviral activity.
Croatian: Nijedan metabolit nije pokazao antivirusno djelovanje in vitro.
English: CORTICOSTEROIDS Fluticasone propionate intranasal 50 µg 4 times daily for 7 days
Croatian: KORTIKOSTEROIDI Flutikazon propionat intranazalno 50 µg 4 puta na dan tijekom 7 dana
English: No teratogenic effects were observed in rats or rabbits at maternally toxic doses.
Croatian: Nisu opaženi teratogeni učinci u štakora ili kunića pri maternalno toksičnim dozama.
English: Assessment of the pharmacokinetics, safety, tolerability, and efficacy of atazanavir is based on data from the open- label, multicenter clinical trial AI424-020 conducted in patients from 3 months to 21 years of age.
Croatian: Procjena farmakokinetike, sigurnosti, podnošljivosti i djelotvornosti atazanavira temelji se na podacima iz multicentričnog kliničkog ispitivanja otvorenog tipa AI424-020 koje je provedeno u bolesnika u dobi od 3 mjeseca do 21 godine.
English: If you take more Atazanavir Mylan than you should Yellowing of the skin and/or eyes (jaundice) and irregular heart beat (QTc prolongation) may occur if you or your child take too much Atazanavir Mylan.
Croatian: Ako uzmete više lijeka Atazanavir Mylan nego što ste trebali Žutilo kože i /ili očiju (žutica) i nepravilni otkucaji srca (produženje QTc interavala) mogu se pojaviti ako Vaše dijete uzme previše lijeka Atazanavir Mylan:
English: There was an increase in the maximum PR interval compared to atazanavir alone.
Croatian: Postoji produljenje maksimalnog PR intervala u usporedbi sa samim atazanavirom.
English: Some people will need special care before or while taking Atazanavir Mylan.
Croatian: Nekim će osobama trebati posebna skrb prije ili tijekom uzimanja lijeka Atazanavir Mylan.
English: High doses of ketoconazole and itraconazole (>200 mg/day) are not recommended.
Croatian: Ne preporučuju se visoke doze ketokonazola i itrakonazola (>200 mg na dan).
English: Patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities during combination antiretroviral therapy and should be monitored according to standard practice.
Croatian: Bolesnici s postojećim poremećajem funkcije jetre, uključujući kronični aktivni hepatitis, imaju povećanu učestalost poremećaja funkcije jetre tijekom kombinirane antiretrovirusne terapije i trebaju biti pod nadzorom sukladno standardnoj praksi.
English: Atazanavir should be administered 2 hours before or 1 hour after antacids or buffered medicinal products.
Croatian: Atazanavir treba primijeniti 2 sata prije ili 1 sat nakon antacida i puferiranih lijekova.
English: Desacetyl-diltiazem Cmax ↑172%
Croatian: Dezacetil-diltiazem Cmax ↑172%
English: Your doctor will discuss with you which combination of these medicines with Atazanavir Mylan is best for you.
Croatian: Liječnik će razgovarati s Vama koja je kombinacija lijekova s lijekom Atazanavir Mylan za Vas najbolja.
English: • Yellowing of your skin or the white part of your eyes caused by high levels of bilirubin in your blood has been commonly reported.
Croatian: • Često je prijavljeno žutilo kože ili bjeloočnica koje je uzrokovano povišenim razinama bilirubina u Vašoj krvi.
English: • peripheral neuropathy (numbness, weakness, tingling or pain in the arms and legs)
Croatian: • periferna neuropatija (utrnulost, slabost, trnci ili bol u rukama i nogama)
English: 3 years For bottles: Use within 90 days of first opening
Croatian: 3 godine Za boce: Iskoristiti u roku od 90 dana od otvaranja
English: If the patient has developed SJS or DRESS associated with the use of atazanavir, atazanavir may not be restarted.
Croatian: Ako je bolesnik razvio SJS ili DRESS povezan s primjenom atazanavira, atazanavir se možda neće ponovno uvesti u terapiju.
English: 14-OH clarithromycin
Croatian: 14-OH klaritromicin
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jirovecii pneumonia.
Croatian: Važni primjeri su citomegalovirusni retinitis, generalizirane i/ili fokalne mikobakterijske infekcije i upala pluća prouzročena gljivicom Pneumocystis jirovecii.
English: There were no tumorigenic findings in male mice or in rats.
Croatian: Nisu se pronašli znakovi tumorogenog djelovanja u mužjaka miša ili u štakora.
English: McDermott Laboratories Limited trading as Gerard Laboratories 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited trading as Gerard Laboratories 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13
English: It is not known whether Atazanavir Mylan with ritonavir administered to the mother during pregnancy will exacerbate physiological hyperbilirubinaemia and lead to kernicterus in neonates and infants.
Croatian: Nije poznato hoće li Atazanavir Mylan s ritonavirom primijenjen majci tijekom trudnoće pogoršati fiziološku hiperbilirubinemiju i dovesti do kernikterusa novorođenčeta i dojenčeta.
English: EXP Once opened: Use within 90 days
Croatian: EXP Nakon otvaranja: iskoristiti u roku od 90 dana
English: Asymptomatic PR interval prolongation was more frequent in paediatric patients than adults.
Croatian: Asimptomatsko produljenje PR intervala bilo je češće u pedijatrijskih bolesnika nego u odraslih.
English: The signs may be a mild yellowing of the skin or eyes.
Croatian: Znakovi mogu biti blago žućkasta boja kože ili bjeloočnica.
English: • quetiapine (used to treat schizophrenia, bipolar disorder and major depressive disorder).
Croatian: • kvetiapin (primjenjuje se za liječenje shizofrenije, bipolarnog poremećaja i velikog depresivnog poremećaja)
English: • hepatosplenomegaly (enlargement of the liver and spleen)
Croatian: • hepatosplenomegalija (povećanje jetre i slezene)
English: Further dosage reduction of rifabutin to 150 mg twice weekly on set days is recommended for patients in whom the 150 mg dose 3 times per week is not tolerated.
Croatian: Daljnje sniženje doze rifabutina na 150 mg dvaput tjedno u određene dane preporučuje se kod bolesnika koji ne podnose dozu od 150 mg 3 puta tjedno.
English: Driving and using machines If you feel dizzy or lightheaded, do not drive or use machines and contact your doctor immediately.
Croatian: Ako osjetite omaglicu ili ošamućenost, nemojte voziti ili upravljati strojevima i odmah se obratite liječniku.
English: In this way Atazanavir Mylan reduces the risk of developing illnesses linked to HIV infection.
Croatian: Tako Atazanavir Mylan smanjuje rizik od razvoja bolesti povezanih s HIV-infekcijom.
English: Tell your doctor if you are using sildenafil for the treatment of erectile dysfunction.
Croatian: Obavijestite svog liječnika ako uzimate sildenafil za liječenje erektilne disfunkcije.
English: Interaction
Croatian: Interakcija
English: PULMONARY ARTERIAL HYPERTENSION PDE5 Inhibitors
Croatian: PLUĆNA ARTERIJSKA HIPERTENZIJA Inhibitori PDE5
English: The clinical data derived from this study are inadequate to support the use of atazanavir (with or without ritonavir) in children below 6 years of age.
Croatian: Klinički podaci iz ovog ispitivanja nisu prikladni da bi se podržala primjena atazanavira (s ritonavirom ili bez njega) u djece mlađe od 6 godina.
English: Sildenafil is also used for the treatment of erectile dysfunction.
Croatian: Sildenafil se također primjenjuje za liječenje erektilne disfunkcije.
English: This association was observed independently of exposure to tenofovir disoproxil.
Croatian: Ta povezanost primijećena je neovisno o izloženosti tenofovirdizoproksilu.
English: If atazanavir is coadministered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Croatian: Ako se atazanavir primjenjuje istovremeno s parenteralnim midazolamom, to treba učiniti u jedinici intenzivnog liječenja (JIL) ili sličnom mjestu koje omogućuje pažljiv klinički nadzor i odgovarajuće zbrinjavanje u slučaju respiratorne depresije i/ili produžene sedacije.
English: • if you require haemodialysis
Croatian: • ako Vam je potrebna hemodijaliza
English: No dose adjustment required for raltegravir.
Croatian: Nije potrebna prilagodba doze za raltegravir.
English: If withdrawal of ritonavir is medically warranted under restrictive conditions (see section 4.4), special attention should be given to atazanavir interactions that may differ in the absence of ritonavir (see information below Table 2).
Croatian: Ako je izostavljanje ritonavira medicinski opravdano, pod restriktivnim uvjetima (vidjeti dio 4.4), posebnu pozornost treba obratiti na interakcije atazanavira koje mogu biti drugačije u odsustvu ritonavira (vidjeti informacije navedene ispod Tablice 2).
English: If necessary, monitor carbamazepine serum concentrations and adjust the dose accordingly.
Croatian: Po potrebi treba nadzirati koncentracije karbamazepina u serumu i u skladu s time prilagoditi dozu.
English: As a result, greater peak to trough ratios are observed, however at recommended doses, geometric mean atazanavir exposures (Cmin, Cax and AUC) in paediatric patients are expected to be similar to those observed in adults.
Croatian: Kao posljedica, opaženi su veći omjeri vršnih i najnižih vrijednosti, no očekuje se da kod preporučenih doza geometrijska sredjna vrijednost izloženosti atazanaviru (Cmin, Cmax i AUC) u pedijatrijskih bolesnika bude slična onoj primjećenoj u odraslih osoba.
English: • sildenafil, vardenafil, or tadalafil (used by men to treat impotence (erectile dysfunction))
Croatian: • sildenafil, vardenafil ili tadalafil (uzimaju ga muškarci za liječenje impotencije (erektilna disfunkcija)
English: • irinotecan (used to treat cancer)
Croatian: • irinotekan (primjenjuje se u liječenju raka)
English: Phenytoin, phenobarbital
Croatian: Fenitoin, fenobarbital
English: While it may contribute to decreased susceptibility to atazanavir when it occurs with other protease substitutions, in clinical studies N88S by itself does not always lead to phenotypic resistance to atazanavir or have a consistent impact on clinical efficacy.
Croatian: Iako N88S može pridonijeti smanjenoj osjetljivosti na atazanavir kad se pojavi s drugim supstitucijama za proteazu, u kliničkim ispitivanjima supstitucija N88S sama po sebi ne dovodi uvijek do fenotipske rezistencije na atazanavir ili ne utječe dosljedno na kliničku djelotvornost.
English: For randomised patients, the mean time of prior antiretroviral exposure was 138 weeks for PIs, 281 weeks for NRTIs, and 85 weeks for NNRTIs.
Croatian: Prosječno trajanje prethodne izloženosti randomiziranih bolesnika antiretrovirusnim lijekovima iznosilo je 138 tjedana za inhibitore proteaze, 281 tjedana za NRTI-jeve i 85 tjedana za NNRTI-jeve.
English: No subject in either group showed emergence of protease inhibitor resistance.
Croatian: Ni u jednoga ispitanika u tim dvjema skupinama nije zabilježen razvoj rezistencije na inhibitore proteaze.
English: Store below 25ºC.
Croatian: Čuvati na temperaturi ispod 25ºC.
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Croatian: Ako primijetite neki od simptoma infekcije ili neke druge simptome kao mišićnu slabost, slabost koja počinje u rukama i nogama i širi se prema trupu, osjećaj lupanja srca, nevoljno drhtanje ili hiperaktivnost, obavijestite odmah svog liječnika i zatražite potrebno liječenje.
English: In pregnant rabbits, gross lesions of the stomach and intestines were observed in dead or moribund does at maternal doses 2 and 4 times the highest dose administered in the definitive embryo-development study.
Croatian: U skotnih ženki kunića opažene su velike lezije na želucu i crijevima u mrtvih ženki kunića ili ženki kunića na umoru pri maternalnim dozama koje su bile 2 ili 4 puta veće od najviše doze primijenjene u zaključnom ispitivanju embrionalnog razvoja.
English: Hard capsule
Croatian: Tvrda kapsula
English: If you have been told by your doctor that you have an intolerance to some sugars (e.g. lactose), contact your doctor before taking this medicinal product.
Croatian: Ako Vam je liječnik rekao da ne podnosite neke šećere (npr., laktozu), obratite se svom liječniku prije nego što uzmete ovaj lijek.
English: The use of Atazanavir Mylan with ritonavir may be considered during pregnancy only if the potential benefit justifies the potential risk.
Croatian: Primjena lijeka Atazanavir Mylan s ritonavirom može se uzeti u obzir tijekom trudnoće samo ako moguća korist opravdava mogući rizik.
English: Fluvastatin is partially metabolised by CYP2C9.
Croatian: Fluvastatin se djelomično metabolizira putem enzima CYP2C9.
English: Generics [UK] Ltd Tel: +44 1707 853000
Croatian: United Kingdom Generics [UK] Ltd Tel: +44 1707 853000
English: The recommended standard treatment is atazanavir boosted with ritonavir, ensuring optimal pharmacokinetic parameters and level of virologic suppression.
Croatian: Preporučeni standardni režim liječenja je atazanavir pojačan ritonavirom, čime se osiguravaju optimalni farmakokinetički parametri i optimalna razina virološke supresije.
English: During in vitro studies, cloned human cardiac potassium channel (hERG), was inhibited by 15% at a concentration (30 μM) of atazanavir corresponding to 30 fold the free drug concentration at Cmax in humans.
Croatian: Tijekom ispitivanja in vitro, klonirani kalijev kanal iz ljudskog srca (hERG) bio je inhibiran za 15% kod koncentracije (30 μM) atazanavira koja je odgovarala 30 puta većoj koncentraciji slobodnog lijeka pri Cmax u ljudi.