FrancophonIA/ELRC3.0 huggingface dataset:
English: Onsenal is used in addition to surgery (to remove the polyps) and endoscopic monitoring (to check if polyps are developing, using an endoscope, a thin tube that allows a doctor to look inside the gut).
Maltese: Onsenal jintuża flimkien mal-kirurġija (għat-tneħħija tal-qarnit) u lmonitoraġġ endoskopiku (biex ikun magħruf jekk ikunux qed jiżviluppaw qarnit, bl-użu ta' l-endoskopu, tubu rqiq li bih it-tabib ikun jista' jara l-ġewwieni tal-passaġġ ta' l-ikel).
English: The full EPAR for Onsenal can be found here.
Maltese: Għaliex ġie approvat Onsenal?
English: Onsenal must not be given to patients with severe liver or kidney problems.
Maltese: Onsenal ma għandux jingħata lil pazjenti bi problemi gravi fil-fwied jew il-kliewi.
English: It must not be used in patients who have an active ulcer or bleeding in the stomach or gut, or in patients who have had allergic-type reactions after taking aspirin or an NSAID, including another COX-2 inhibitor.
Maltese: Ma għandux jintuża f'pazjenti b'ulċera attiva jew fsada fl-istonku jew fil-musrana jew f'pazjenti li kellhom reazzjonijiet ta' tip allerġiku wara li ħadu aspirina jew NSAID, inkluż inibitur tal-COX-2 ieħor).
English: By blocking the activity of COX-2, celecoxib helps to slow down the formation of polyps by stopping them developing their own blood supply and by increasing the rate of cell death.
Maltese: Billi jimblokka l-attività tal-COX-2, celecoxib jgħin biex inaqqas il-veloċità li biha l-polipi jiffurmaw ruħhom billi jwaqqafhom milli jiżviluppaw il-provvista ta' demm tagħhom stess u billi jżid il-veloċità tal-mewt taċ-ċelluli.
English: In the study, 25 patients had an intact colon, but the remainder had had some or all of their colon removed through surgery.
Maltese: Fl-istudju, 25 pazjent kellhom kolon intatt, iżda l-bqija tal-pazjenti kien tneħħielhom il-kolon tagħhom kollu jew parti minnu b'intervent kirurġiku.
English: What benefit has Onsenal shown during the studies?
Maltese: Kif ġie studjat Onsenal?
English: For the full list of all side effects reported with Onsenal, see the
Maltese: Għal-lista sħiħa tal-effetti sekondarji rrappurtati ma' Onsenal ara l-Fuljett ta' Tagħrif.
English: 50 capsules
Maltese: 50 kapsula
English: Tel. +31 (0)20 6615 072 info@diurnal.co.uk
Maltese: +31 (0)20 6615 072 info@diurnal.co.uk
English: Delpharm Lille SAS Parc d'Activités Roubaix-Est 22 rue de Toufflers CS 50070 Lys Lez Lannoy, 59 452 France
Maltese: Delpharm Lille SAS Parc d'Activités Roubaix-Est 22 rue de Toufflers CS 50070 Lys Lez Lannoy, 59 452 Franza
English: Van Heuven Goedhartlaan 935 A 1181LD Amstelveen The Netherlands
Maltese: Van Heuven Goedhartlaan 935 A 1181LD Amstelveen In-Netherlands
English: ATC code: H02AB09
Maltese: H02AB09
English: Capsule Hypromellose
Maltese: Kapsula Hypromellose
English: No antidote is available.
Maltese: M'hemm l-ebda antidotu disponibbli.
English: The biological half-life of hydrocortisone is about 100 minutes.
Maltese: Il-half life bijoloġika ta' hydrocortisone hija madwar 100 minuta.
English: Alkindi comes in high density polyethylene plastic bottles containing 50 capsules.
Maltese: Alkindi jiġi fi fliexken tal-plastik high density polyethylene li fihom 50 kapsula.
English: 1 mg (blue)
Maltese: 1 mg (blu)
English: Hydrocortisone is a glucocorticoid.
Maltese: Hydrocortisone huwa glukokortikojd.
English: Do not swallow the capsule, risk of choking.
Maltese: Tiblax il-kapsula, hemm riskju ta' fgar.
English: Fertility There are no data available for possible effects of Alkindi on fertility.
Maltese: Fertilità M'hemmx data disponibbli dwar effetti possibbli ta' Alkindi fuq il-fertilità.
English: In all 24 patients Alkindi was found to increase cortisol values from baseline as expected: median baseline cortisol 14.1 mmol/l (range 14.1 - 104.5), median Cmax 535.2 mmol/l (range 346.2 - 1445.1).
Maltese: F'kull wieħed mill-24 pazjent instab li Alkindi żied il-valur ta' cortisol mill-linja bażi kif mistenni: il-linja bażi medjana ta' cortisol 14.1 mmol/l (medda 14.1 - 104.5), medjan Cmax 535.2 mmol/l (medda 346.2 - 1445.1).
English: Date of first authorisation: 09 February 2018
Maltese: Data tal-ewwel awtorizzazzjoni: 09 ta' Frar 2018
English: Distribution 90% or more of circulating hydrocortisone is reversibly bound to protein.
Maltese: Distribuzzjoni 90% jew aktar ta' hydrocortisone fiċ-ċirkulazzjoni huwa marbut b'mod riversibbli mal-proteini.
English: These include: - Grapefruit juice.
Maltese: - Meraq tal-grejpfrut.
English: Hydrocortisone is metabolised by cytochrome P450 3A4 (CYP3A4).
Maltese: Interazzjoni ma' prodotti mediċinali oħra u forom oħra ta' interazzjoni Hydrocortisone jiġi metabolizzat permezz taċ-ċitokromu P450 3A4 (CYP3A4).
English: - Anticonvulsants: phenytoin, carbamazepine and oxcarbazepine - Antibiotics: rifampicin and rifabutin - Barbiturates including phenobarbital and primidone - Antiretroviral medicinal products: efavirenz and nevirapine
Maltese: - Antibijotiċi: rifampicin u rifabutin - Barbiturati inkluż phenobarbital u primidone - Prodotti mediċinali antiretrovirali: efavirenz u nevirapine
English: Studies in animals have shown reproductive toxicity of corticosteroids (see section 5.3)
Maltese: Studji f'annimali wrew tossiċità riproduttiva ta' kortikosterojdi (ara sezzjoni 5.3).
English: - The active substance is hydrocortisone - Alkindi 0.5 mg granules in capsules for opening: each capsule contains 0.5 mg of hydrocortisone - Alkindi 1 mg granules in capsules for opening: each capsule contains 1 mg of hydrocortisone - Alkindi 2 mg granules in capsules for opening: each capsule contains 2 mg of hydrocortisone - Alkindi 5 mg granules in capsules for opening: each capsule contains 5 mg of hydrocortisone - The other ingredients are microcrystalline cellulose, hypromellose, magnesium stearate and ethyl cellulose.
Maltese: - Alkindi 0.5 mg granijiet f'kapsuli għall-ftuħ: kull kapsula fiha 0.5 mg ta' hydrocortisone - Alkindi 1 mg granijiet f'kapsuli għall-ftuħ: kull kapsula fiha 1 mg ta' hydrocortisone - Granijiet Alkindi ta' 2 mg f'kapsuli għall-ftuħ: kull kapsula fiha 2 mg ta' hydrocortisone - Granijiet Alkindi ta' 5 mg f'kapsuli għall-ftuħ: kull kapsula fiha 5 mg ta' hydrocortisone
English: - Medicine used to treat human immunodeficiency virus (HIV) infection and AIDS: ritonavir.
Maltese: - Mediċina li tintuża għat-trattament ta' infezzjoni tal-virus tal-immunodefiċjenza umana (human immunodeficiency virus - HIV) u tal-AIDS: ritonavir.
English: Patients/and or carers should be warned that potentially severe psychiatric adverse reactions; euphoria, mania, psychosis with hallucinations and delirium have been seen in adult patients at replacement doses of hydrocortisone (see section 4.8).
Maltese: Pazjenti u/jew dawk li jieħdu ħsiebhom għandhom jiġu mwissija li reazzjonijiet avversi psikjatriċi potenzjalment severi; ewforija, manija, psikosi b'alluċinazzjonijiet u delirju ġew osservati f'pazjenti adulti f'dożi ta' sostituzzjoni ta' hydrocortisone (ara sezzjoni 4.8).
English: 5 mg (grey)
Maltese: 5 mg (griż)
English: Among parents and carers asked about their child's experience of taking the medication (n=23), 82.6% agreed/strongly agreed that their child found swallowing Alkindi easy; 65.2% agreed/strongly agreed that their child showed a positive reaction after Alkindi administration; 95.5% would be happy to give their child Alkindi in the future; and 95.5% said that they would prefer Alkindi for their child's treatment over their usual hydrocortisone formulation.
Maltese: Fost ġenituri u dawk li jieħdu ħsieb il-pazjent li ġew mistoqsija dwar l-esperjenza tat-tifel/tifla tagħhom dwar it-teħid tal--mediċina (n=23), 82.6% qablu/qablu bis-sħiħ li t-tifel/tifla sab/et Alkindi faċli biex jinbela'; 65.2% qablu/qablu bis-sħiħ li t-tifel/tifla tagħhom urew reazzjoni pożittiva wara l-għoti ta' Alkindi; 95.5% ikunu kuntenti jagħtu Alkindi lit-tifel/tifla tagħhom fil-futur; u 95.5% qalu li jippreferu Alkindi għall-kura tattifel/tifla tagħhom mill-formula ta' hydrocortisone li jużaw normalment.
English: 0.5 mg (red)
Maltese: 0.5 mg (aħmar)
English: intense feeling of happiness and excitement (euphoria).
Maltese: sentiment qawwi ta' ferħ u eċitament (ewforija).
English: - Keep this leaflet.
Maltese: Eskrement ta' granijiet.
English: Alkindi contains a medicine called hydrocortisone.
Maltese: Alkindi fih mediċina msejħa hydrocortisone.
English: Replacement therapy in primary and secondary adrenal insufficiency Alkindi is given as replacement therapy by oral administration of granules according to clinical practice, in a dose to be titrated against individual clinical response.
Maltese: Terapija ta' sostituzzjoni f'insuffiċjenza adrenali primarja u sekondarja Alkindi jingħata bħala terapija ta' sostituzzjoni permezz ta' amministrazzjoni mill-ħalq ta' granijiet skont il-prassi klinika, f'doża li għandha tiġi aġġustata kontra r-rispons kliniku individwali.
English: Medicines used to treat AIDS: efavirenz and nevirapine.
Maltese: Mediċini li jintużaw għat-trattament tal-AIDS: efavirenz u nevirapine.
English: There is no information on any effects of Alkindi on fertility.
Maltese: M'hemmx informazzjoni dwar effetti ta' Alkindi fuq il-fertilità.
English: Alkindi is therapeutically equivalent to conventional hydrocortisone tablets.
Maltese: Alkindi hija terapewtikament ekwivalenti għal pinnoli ta' hydrocortisone konvenzjonali.
English: The capsule is printed with "INF-1.0" in blue ink.
Maltese: Il-kapsula hija stampata bil-kitba "INF-1.0" b'linka blu.
English: All inks contain Shellac, Propylene glycol, Concentrated ammonia solution
Maltese: Il-linka kollha fiha Shellac, Propylene glycol, soluzzjoni ta' ammonja konċentrata
English: - due for an operation.
Maltese: - wasal/waslet għal operazzjoni.
English: The pivotal study was an open-label single-dose single-centre trial in 24 paediatric patients aged less than 6 years requiring replacement therapy for adrenal insufficiency due to CAH, primary adrenal failure or hypopituitarism.
Maltese: L-istudju ċentrali kien prova open-label b'doża waħda f'ċentru wieħed f'24 pazjent pedjatriku ta' anqas minn 6 snin li kienu jeħtieġu terapija ta'sostituzzjoni għal insuffiċjenza adrenali minħabba CAH, falliment adrenali primarju jew ipopitwitariżmu (hypopituitarism).
English: - Anti-fungals: itraconazole, posaconazole, voriconazole - Antibiotics: erythromycin and clarithromycin - Antiretroviral medicinal products: ritonavir - Grapefruit juice
Maltese: - Antibijotiċi: erythromycin u clarithromycin - Prodotti mediċinali antiretrovirali: ritonavir
English: Hydrocortisone is a synthetic version of the hormone cortisol.
Maltese: Hydrocortisone huwa verżjoni sintetika tal-ormon cortisol.
English: Medicinal products/substances inhibiting CYP3A4, requiring a potential decrease in Alkindi dosing, include but are not limited to:
Maltese: Prodotti mediċinali/sustanzi li jinibixxu CYP3A4, u għalhekk potenzjalment jirrikjedu tnaqqis fiddożaġġ ta' Alkindi, jinkludu iżda mhumiex limitati għal:
English: Medicines used to treat infections (antibiotics): rifampicin and rifabutin.
Maltese: Mediċini li jintużaw għat-trattament tal-infezzjonijiet (antibijotiċi): rifampicin u rifabutin.
English: Other medicines and Alkindi
Maltese: Mediċini oħra u Alkindi
English: Replacement therapy of adrenal insufficiency in infants, children and adolescents (from birth to < 18 years old).
Maltese: Terapija ta' sostituzzjoni għal insuffiċjenza adrenali fit-trabi, fit-tfal u fl-adolexxenti (mit-twelid sa < 18-il sena).
English: Pharmacotherapeutic group: Corticosteroids for systemic use; Glucocorticoids.
Maltese: Kortikosterojdi għal użu sistemiku; Glukokortikojdi.
English: The terminal half-life of hydrocortisone is about 1.5 hours following intravenous and oral dosing of hydrocortisone tablets and Alkindi in dexamethasone-suppressed healthy adult male volunteers.
Maltese: Il-half life terminali ta' hydrocortisone hija madwar 1.5 sigħat (siegħa u nofs) wara dożaġġ fil-vini u mill-ħalq ta' pinnoli tal-hydrocortisone u Alkindi f'voluntiera rġiel adulti b'saħħithom li għandhom soppressjoni ta' dexamethasone.
English: Recommended replacement doses of hydrocortisone are 8-10 mg/m2/day for patients with adrenal insufficiency alone and 10-15 mg/m2/day in patients with congenital adrenal hyperplasia (CAH), typically in three or four divided doses.
Maltese: Id-dożi ta' sostituzzjoni rakkomandati ta' hydrocortisone huma bejn 8-10 mg/m2/jum għal pazjenti b'insuffiċjenza adrenali biss u 10-15 mg/m2/jum għal pazjenti b'iperplasja adrenali konġenitali
English: The ink on the 1 mg strength capsule also contains indigotine (E132).
Maltese: Il-linka fuq il-kapsula ta' qawwa 1 mg fiha wkoll indigotine (E132).
English: Reports of acute toxicity and/or deaths following hydrocortisone overdose are rare.
Maltese: .9 Doża eċċessiva Rapporti ta' tossiċità akuta u/jew ta' mwiet wara doża eċċessiva ta' hydrocortisone huma rari.
English: 2 mg (green)
Maltese: 2 mg (aħdar)
English: - The capsule is made from hypromellose.
Maltese: - Il-kapsula hija magħmula minn hypromellose.
English: Granules
Maltese: UŻU
English: One, corticosteroid-binding globulin is a glycoprotein; the other is albumin.
Maltese: Waħda, globulina li torbot il kortikosterojdihija glikoproteina; l-oħra hija albumina.
English: - Medicines used to treat infections (antibiotics): erythromycin and clarithromycin.
Maltese: - Mediċini li jintużaw għat-trattament tal-infezzjonijiet (antibijotiċi): erythromycin u clarithromycin.
English: overexcitement and overactivity (mania).
Maltese: (alluċinazzjonijiet) u konfużjoni mentali (delirju). - eċċitament żejjed u attività żejda (manija).
English: Medicines that may mean your endocrinologist will decrease your child's dose of Alkindi include: - Medicines used to treat fungal diseases: itraconazole, posaconazole, and voriconazole.
Maltese: - Mediċini li jintużaw għat-trattament ta' mard fungali: itraconazole, posaconazole, u voriconazole.
English: Medicines called barbiturates, which can be used to treat convulsions (including phenobarbital and primidone).
Maltese: Mediċini li jissejħu barbiturati, li jistgħu jintużaw għat-trattament tal-konvulsjonijiet (inkluż phenobarbital u primidone).
English: Psychosis with hallucinations and delirium Mania
Maltese: Psikosi b'alluċinazzjonijiet u delirju
English: The ink on the 5 mg strength capsule also contains potassium hydroxide, titanium dioxide (E171), and black iron oxide (E172).
Maltese: Il-linka fuq il-kapsula ta' qawwa 5 mg fiha wkoll potassium hydroxide, titanium dioxide (E171), u black iron oxide (E172).
English: Following oral administration, hydrocortisone is rapidly absorbed from the gastro-intestinal tract and the oral Alkindi 4x5 mg was approximately 87 % bioavailable when compared to intravenous hydrocortisone in dexamethasone-suppressed healthy adult male volunteers.
Maltese: Wara għoti mill-ħalq, hydrocortisone jiġi assorbit malajr mill-passaġġ gastrointestinali u Alkindi għal għoti mill-ħalq 4x5 mg kienet madwar 87 % biodisponibbli meta mqabbla ma' hydrocortisone fil-vina f'voluntiera rġiel adulti f'saħħithom li għandhom soppressjoni ta' dexamethasone.
English: The capsule is printed with "INF-5.0" in grey ink.
Maltese: Il-kapsula hija stampata bil-kitba "INF-5.0" b'linka griża.
English: - The printing ink on the capsules contains shellac, propylene glycol, and concentrated ammonia solution.
Maltese: - Il-linka tal-istampar fuq il-kapsuli fiha shellac, propylene glycol, u soluzzjoni ta' ammonja konċentrata.
English: Six of the 12 children in Cohort 1 (age range 2.6 to 4.7 years) responded to an adjusted palatability questionnaire.
Maltese: Sitta mit-12-il tifel u tifla fi Grupp 1 (età ta' bejn 2.6 u 4.7 snin) wieġbu għal kwestjonarju aġġustat dwar il-palatabilità (togħma).
English: Undesirable effects of corticosteroid replacement therapy Most undesirable effects of corticosteroids are dose and duration of exposure related.
Maltese: Effetti mhux mixtieqa ta' terapija ta' sostituzzjoni ta' kortikosterojdi Ħafna mill-effetti mhux mixtieqa ta' kortikosterojdi huma relatati mad-doża u mad-dewmien tal esponiment.
English: The study consisted of three consecutive cohorts, the first including 12 patients aged 2 to less than 6 years, the second including 6 patients aged 28 days to less than 2 years, and the third including 6 neonates aged from birth to less than 28 days.
Maltese: L-istudju kien jikkonsisti fi tliet gruppi konsekuttivi, l-ewwel wieħed kien fih 12-il pazjent minn età ta' sentejn (2) sa anqas minn 6 snin, it-tieni kien fih 6 pazjenti minn età ta' 28 jum sa anqas minn sentejn (2), u t-tielet kien fih 6 trabi tat-twelid minn età tat-twelid sa anqas minn 28 jum.
English: 1 patient had renal hypoplasia, 1 patient atopic dermatitis and 1 patient had rhinitis.
Maltese: Pazjent 1 kellu ipoplażja renali, pazjent 1 dermatite atopika u pazjent 1 kellu r-rinite.
English: The ink on the 2 mg strength capsule also contains indigotine (E132), yellow iron oxide (E172), and titanium dioxide (E171).
Maltese: Il-linka fuq il-kapsula ta' qawwa 2 mg fiha wkoll indigotine (E132), yellow iron oxide (E172), u titanium dioxide (E171).
English: - Alkindi 2 mg granules in capsules for opening: the capsule is printed with "INF-2.0" in green ink.
Maltese: - Alkindi 2 mg granijiet f'kapsuli għall-ftuħ: il-kapsula hija stampata bil-kitba "INF-2.0" blinka ħadra.
English: Strength (ink colour) Also contains:
Maltese: - Bidliet fl-imġiba inkluż:
English: Pregnancy, breast-feeding and fertility
Maltese: - Meraq tal-grejpfrut - Liquorice
English: Each capsule contains 0.5 mg hydrocortisone.
Maltese: Kull kapsula fiha 0.5 mg ta' hydrocortisone.
English: - Alkindi 0.5 mg granules in capsules for opening: the capsule is printed with "INF-0.5" in red ink.
Maltese: - Alkindi 0.5 mg granijiet f'kapsuli għall-ftuħ: il-kapsula hija stampata bil-kitba "INF-0.5"
English: How to store Alkindi
Maltese: X'fih Alkindi
English: Alkindi 0.5 mg granules in capsules for opening Alkindi 1 mg granules in capsules for opening Alkindi 2 mg granules in capsules for opening Alkindi 5 mg granules in capsules for opening
Maltese: Alkindi 0.5 mg granijiet f'kapsuli għall-ftuħ Alkindi 1 mg granijiet f'kapsuli għall-ftuħ Alkindi 2 mg granijiet f'kapsuli għall-ftuħ Alkindi 5 mg granijiet f'kapsuli għall-ftuħ
English: Historical cohorts of adults treated from childhood for CAH have been found to have reduced bone mineral density and increased fracture rates and growth retardation (see section 4.4) - it is unclear if these relate to hydrocortisone therapy using current replacement regimens.
Maltese: Gruppi storiċi ta' adulti ttrattati għal CAH mit-tfulija nstabu li għandhom anqas densità minerali tal għadam u rati ogħla ta' ksur u dewmien fit-tkabbir (ara sezzjoni 4.4) - mhuwiex ċar jekk dawn jirrelatawx ma' terapija ta' hydrocortisone li tuża metodi ta' sostituzzjoni attwali.
English: Glucocorticoids cause profound and varied metabolic effects.
Maltese: Il-glukokortikojds jikkawżaw effetti metaboliċi qawwija u varji.
English: Infection should not be more likely at a replacement dose of hydrocortisone, but all infections should be treated seriously and stress dosing of steroid initiated early (see section 4.2).
Maltese: Infezzjoni m'għandhiex tkun aktar probabbli b'doża ta' sostituzzjoni ta' hydrocortisone, iżda l infezzjonijiet kollha għandhom jiġu trattati bis-serjetà u doża ta' sterojdi waqt perjodu ta' stress għandha tinbeda kmieni (ara sezzjoni 4.2).
English: Each capsule contains 2 mg hydrocortisone.
Maltese: Kull kapsula fiha 2 mg ta' hydrocortisone.
English: Each capsule contains 1 mg hydrocortisone.
Maltese: Kull kapsula fiha 1 mg ta' hydrocortisone.
English: As this was a single-dose study, the primary efficacy assessment was serum cortisol at 60 minutes.
Maltese: Peress li dan kien studju ta' doża waħda, l-assessjar primarju tal-effikaċja kien cortisol fis-serum wara 60 minuta.
English: Each capsule contains 5 mg hydrocortisone.
Maltese: Kull kapsula fiha 5 mg ta' hydrocortisone.
English: In less severe situations when parenteral administration of hydrocortisone is not required, for instance low grade infections, moderate fever of any aetiology and stressful situations such as minor surgical procedures, there should be high awareness of the risk of developing acute adrenal insufficiency, and the normal oral daily replacement dose should be increased temporarily; the Alkindi total daily dose should be increased by doubling or tripling the usual dose.
Maltese: F'sitwazzjonijiet anqas gravi meta ma jkunx meħtieġ l-għotimgħarfa tal-hydrocortisone ġol-vini, pereżempju infezzjonijiet ta' grad baxx, deni moderat ta' kwalunkwe kawża u sitwazzjonijiet stressanti bħal proċeduri kirurġiċi minuri, għandu jkun hemm livell għoli ta' għarfien tar-riskju li tiżviluppa insuffiċjenza adrenali akuta, u d-doża normali ta' sostituzzjoni li tittieħed kuljum mill-ħalq għandha tiżdied b'mod temporanju; id-doża totali ta' kuljum ta' Alkindi għandha tiżdied billi d-doża normali tiġi rduppjata jew tripplikata.
English: Hydrocortisone is metabolised in the liver and most body tissues to hydrogenated and degraded forms such as tetrahydrocortisone and tetrahydrocortisol which are excreted in the urine, mainly conjugated as glucuronides, together with a very small proportion of unchanged hydrocortisone.
Maltese: Hydrocortisone huwa metabolizzat fil-fwied u f'ħafna mit-tessuti tal-ġisem għal forom idroġenati u degradati bħal tetrahydrocortisone u tetrahydrocortisol li huma mneħħija fl-awrina, prinċipalment konjugati bħala glukuronidi, flimkien ma' proporzjon żgħir ħafna ta' hydrocortisone mhux mibdul.
English: Parenteral administration of hydrocortisone is warranted during transient illness episodes such as severe infections, in particular gastroenteritis associated with vomiting and/or diarrhoea, high fever of any aetiology or extensive physical stress, such as for instance serious accidents and surgery under general anaesthesia.
Maltese: L-għoti ta' hydrocortisone ġol-vini hija ġġustifikata waqt episodji ta' mard tranżitorju bħal infezzjonijiet severi, b'mod partikolari l-gastroenterite assoċjata ma' rimettar u/jew dijarea, deni għoli ta' kwalunkwe kawża jew stress fiżiku estensiv, bħal pereżempju inċidenti serji u kirurġija taħt anestesija ġenerali.
English: The ink on the 0.5 mg strength capsule also contains potassium hydroxide and red iron oxide (E172).
Maltese: Il-linka fuq il-kapsula ta' qawwa 0.5 mg fiha wkoll potassium hydroxide u red iron oxide (E172).
English: The coadministration of Alkindi with soft food (yoghurt and fruit puree) has been studied in vitro with no significant effect on dissolution seen.
Maltese: L-għoti flimkien ta' Alkindi ma' ikel artab (jogurt u purè tal-frott) ġie studjat in vitro u ma ġie osservat l-ebda effett sinifikanti fuq it-taħlil (dissolution).
English: - Alkindi 1 mg granules in capsules for opening: the capsule is printed with "INF-1.0" in blue ink.
Maltese: - Granijiet Alkindi ta' 1 mg f'kapsuli għall-ftuħ: il-kapsula hija stampata bil-kitba "INF-1.0"
English: Medicines that may mean your endocrinologist will increase your child's dose of Alkindi include: Medicines used to treat epilepsy: phenytoin, carbamazepine, and oxcarbazepine.
Maltese: Mediċini li jistgħu jfissru li l-endokrinologu tiegħek se jżid id-doża ta' Alkindi għat-tifel/tifla tiegħek jinkludu: Mediċini li jintużaw għat-trattament tal-epilessija: phenytoin, carbamazepine, u oxcarbazepine.
English: Pack sizes: 1 bottle containing 50 capsules
Maltese: Flixkun wieħed fih 50 kapsula
English: Naturally-occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states.
Maltese: Il-glukokortikojds li jseħħu b'mod naturali (hydrocortisone u cortisone), li għandhom ukoll karatteristiċi li jżommu l-melħ, jintużaw bħala terapija ta' sostituzzjoni fi stati ta' defiċjenza adrenokortikali.
English: Glucocorticoids are adrenocortical steroids, both naturally-occurring and synthetic, which are readily absorbed from the gastro-intestinal tract.
Maltese: Glukokortikojds huma sterojdi adrenokortikali, li jseħħu kemm b'mod naturali kif ukoll b'mod sintetiku, li huma assorbiti faċilment mill-passaġġ gastrointestinali.