FrancophonIA/ELRC3.0 huggingface dataset:
English: A large international long-term term study of treatment for neonatal diabetes due to KCNJ11 mutations is ongoing and results were reported in 81 patients of the 90 patients originally included with a median [interquartile range] follow-up duration of 10.2 years [9.3-10.8 years].
Croatian: Veliko međunarodno dugoročno ispitivanje u vezi s liječenjem neonatalnog dijabetesa uzrokovanog mutacijama gena KCNJ11 trenutačno je u tijeku te su objavljeni rezultati za 81 od 90 inicijalno uključenih ispitanika s medijanom [interkvartilni raspon (IQR)] trajanja praćenja od 10,2 godine [9,3
English: This medicine contains 2.80 mg of sodium per mL.
Croatian: Ovaj lijek sadrži 2,80 mg natrija po ml.
English: In addition undesirable effects gathered from the use in adults is of importance given the small database in children.
Croatian: Nadalje, nuspojave zabilježene kod odraslih važne su jer su podaci o nuspojavama u djece ograničeni.
English: The attending specialist should then be contacted.
Croatian: Treba se obratiti odgovarajućem liječniku specijalistu.
English: If your child's capillary blood sugar exceeds 3 g/L (or 300 mg/dL or 16.5 mmol/L), check for the presence of ketonuria with a finger stick or urine stick tests according to your child's doctor recommendations.
Croatian: Ako razina šećera u kapilarnoj krvi vašeg djeteta prekoračuje 3 g/l (ili 300 mg/dl ili 16,5 mmol/l), provjerite prisutnost ketonurije pomoću urinarnog štapića ili testa za urin u skladu s preporukama liječnika vašeg djeteta.
English: If ketone bodies are present, an insulin injection must be given rapidly to restore the metabolic situation.
Croatian: Ako se ustanovi prisutnost ketona, treba što prije primijeniti injekciju inzulina radi obnove metaboličke situacije.
English: In patients carrying a G6PD enzyme deficiency, cases of acute haemolytic anaemia have been reported with glibenclamide.
Croatian: U bolesnika s nedostatkom enzima G6PD zabilježeni su slučajevi akutne hemolitičke anemije nakon primjene glibenklamida.
English: Turn the bottle with the syringe into its upright position.
Croatian: Bočicu sa štrcaljkom okrenite u uspravan položaj.
English: Nausea, vomiting, flushing, dizziness, headache, chest and abdominal discomfort, and general hangover-like symptoms among others have occurred following the concomitant use of alcohol and glibenclamide.
Croatian: Mučnina, povraćanje, navale crvenila, vrtoglavica, glavobolja, nelagoda u trbuhu i prsima, kao i opći simptomi slični mamurluku među ostalima pojavili su se nakon istodobne primjene alkohola i glibenklamida.
English: Oxypentifylline used to improve peripheral blood flow
Croatian: Oksipentifilin koji se upotrebljava za poboljšanje perifernog protoka krvi
English: Reduction of glibenclamide absorption from the gastrointestinal tract
Croatian: Smanjenje apsorpcije glibenklamida iz gastrointestinalnog trakta
English: This must be followed by continuous infusion of more dilute glucose solution (10%) at the rate needed to maintain blood-glucose above 100 mg/dL (100 mg/dL = 5.5 mmol/L).
Croatian: Nakon toga potrebno je kontinuirano davati infuziju razrjeđenije otopine glukoze (10 %) brzinom koja je potreban za održavanje glukoze u krvi iznad 100 mg/dl (100 mg/dl =
English: As soon as insulin is discontinued, the dose of AMGLIDIA is adjusted according to capillary blood glucose.
Croatian: Čim se prekine uzimanje inzulina, doza lijeka AMGLIDIA prilagođava se ovisno o glukozi u kapilarnoj krvi.
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients hydroxyethylcellulose lactic acid purified water sodium benzoate (E211) sodium citrate xanthan gum
Croatian: 6.1 Popis pomoćnih tvari hidroksietilceluloza laktatna kiselina pročišćena voda natrijev benzoat (E211) natrijev citrat ksantanska guma
English: Neonatal diabetes is a disease where the child's body does not release enough insulin to control the level of blood sugar; AMGLIDIA is used only in patients who still have some ability to make insulin.
Croatian: Neonatalni dijabetes jest bolest kod koje tijelo djeteta ne ispušta dovoljnu količinu inzulina za kontrolu razine šećera u krvi; AMGLIDIA se primjenjuje samo u bolesnika koji i dalje mogu donekle stvarati inzulin.
English: To limit exposure to sodium benzoate and with respect to the mode of delivery (1 mL and 5 mL oral syringes), it is not recommended to use the AMGLIDIA 0.6 mg/mL strength for posologies higher than the ones described below:
Croatian: Radi ograničavanja izloženosti natrijevu benzoatu i s obzirom na način primjene (štrcaljkom za usta od 1 ml i 5 ml), ne preporučuje se upotreba lijeka AMGLIDIA jačine 0,6 mg/ml za doze veće od onih navedenih u nastavku:
English: Disulfiram-like reactions have occurred very rarely following the concomitant use of alcohol and glibenclamide.
Croatian: Reakcije slične reakcijama nakon primjene disulfirama pojavile su se u vrlo rijetkim slučajevima nakon istodobne primjene alkohola i glibenklamida.
English: Finally, draw back the plunger until graduation corresponding to the prescribed dose in ml (figure 4C).
Croatian: Konačno, povucite klip prema natrag do oznake ml koja se podudara s propisanom dozom (slika 4C).
English: Treatment using sulphonylureas in neonatal diabetes linked to potassium channel disorders is supported by published studies showing measurable improvements in glycaemic control and suggesting neuro-psychomotor and neuro-psychological deficiencies, which are greater in younger patients.
Croatian: Liječenje neonatalnog dijabetesa povezanog s poremećajima kalijevih kanala pomoću sulfonilureja podržavaju objavljena ispitivanja koja pokazuju mjerljiva poboljšanja u kontroli glikemije i upućuju na neurološke psihomotoričke i neurološke fiziološke nedostatke koji su veći u mlađih bolesnika.
English: Throughout the transfer period, administer bolus insulin or insulin pump boluses with meals as required to maintain reasonable glycemic control.
Croatian: Tijekom prijelaznog razdoblja potrebno je primjenjivati bolusni inzulin ili boluse inzulinskom pumpom uz obroke da bi se održala razumna kontrola glikemije.
English: Quinolone antibiotics
Croatian: Antibiotici kinoloni
English: Bioavailability studies have demonstrated that nonmicronised tablets provide serum glibenclamide concentrations that are not bioequivalent to those from micronised tablets.
Croatian: Ispitivanja bioraspoloživosti pokazala su da nemikronizirane tablete rezultiraju koncentracijama glibenklamida u serumu koje nisu bioekvivalentne koncentracijama mikroniziranih tableta.
English: If it is necessary to prescribe this medicinal product, screening should be conducted for the occurrence of any haemolysis.
Croatian: Ako je potrebno propisati ovaj lijek, treba provoditi preglede kako bi se utvrdilo je li nastala hemoliza.
English: The screw cap should then be replaced on the bottle with the adaptor and not removed during the 30-day use.
Croatian: Zatim treba navojni zatvarač bočice vratiti na bočicu s nastavkom koji se ne smije uklanjati tijekom 30-dnevne uporabe.
English: Increase ciclosporin plasma concentration
Croatian: Povećanje koncentracije ciklosporina u plazmi
English: Barbiturates (such as phenobarbital used to treat epilepsy)
Croatian: Barbiturati (kao što je fenobarbital koji se upotrebljava za liječenje epilepsije)
English: Women of childbearing potential planning a pregnancy should be switched from oral glibenclamide to insulin.
Croatian: Žene reproduktivne dobi koje planiraju trudnoću trebaju prijeći s uporabe oralnog glibenklamida na inzulin.
English: Holding the bottle the right way up, insert the syringe firmly into the adaptor fitted to the bottle (figure 2).
Croatian: Dok držite bočicu u odgovarajućem uspravnom položaju, štrcaljku umetnite čvrsto u nastavak pričvršćen na bočicu (slika 2).
English: Guanethidine used to treat high blood pressure
Croatian: Gvanetidin koji se upotrebljava za liječenje visokog krvnog tlaka
English: It should therefore not be prescribed for these patients, and the use of an alternative treatment is strongly recommended, if available.
Croatian: Strogo se preporučuje uporaba alternativnoga liječenja, ako je dostupno.
English: Diarrhea, nausea and vomiting
Croatian: Proljev, mučnina i povraćanje
English: Ifosfamide used to treat different types of cancers
Croatian: Ifosfamid koji se upotrebljava za liječenje različitih vrsta raka
English: o For major surgery, insulin therapy should replace AMGLIDIA; o Hepatic or renal dysfunction may require a reduction in dosage; o In exceptional situations of stress (e.g. trauma, surgery, febrile infections), blood-glucose regulation may deteriorate, and a temporary change to insulin may be necessary to maintain good metabolic control.
Croatian: o pri disfunkciji jetre ili bubrega može biti potrebno smanjenje doze; o u iznimnim situacijama stresa (npr. trauma, operacija, febrilne infekcije), regulacija glukoze u krvi može se pogoršati te će možda biti potrebno privremeno prijeći na inzulinsku terapiju radi održavanja dobre metaboličke kontrole.
English: Each mL contains 2.8 mg of sodium and 5 mg of benzoate salt.
Croatian: Jedan ml sadrži 2,8 mg natrija i 5 mg benzoata.
English: Liver failure reduces the metabolism of glibenclamide and therefore significantly slows down its elimination.
Croatian: Zatajenje jetre smanjuje metabolizam glibenklamida te stoga značajno usporava njegovu eliminaciju.
English: From data published in the literature, treatment with sulfonylurea is reported to be successful in approximately 90% of the patients with neonatal diabetes associated with K-ATP channel mutations.
Croatian: Prema podacima iz literature liječenje sulfonilurejom uspješno je u približno 90 % bolesnika s neonatalnim dijabetesom povezanim s mutacijama K-ATP kanala.
English: Biliary excretion of the metabolites increases in the event of kidney failure, proportionally to the severity of the change in renal function.
Croatian: Izlučivanje metabolita putem žuči povećava se u slučaju zatajenja bubrega, proporcionalno ozbiljnosti promjene u funkciji bubrega.
English: Anaphylactic reaction including dyspnoea, hypotension and shock.
Croatian: Poremećaji imunološkog sustava Anafilaktička reakcija, uključujući dispneju, hipotenziju i šok.
English: A. MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION
Croatian: PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET B. UVJETI ILI OGRANIČENJA VEZANI UZ OPSKRBU I PRIMJENU
English: Heparin used to decrease the clotting ability of the blood
Croatian: Heparin koji se upotrebljava za smanjenje sposobnosti zgrušavanja krvi
English: During titration period patients' capillary blood-glucose concentration should continue to be monitored four times a day and at bedtime, as insulin requirements may continue to fall, or AMGLIDIA may need to be titrated.
Croatian: Tijekom titracijskog razdoblja koncentraciju glukoze u kapilarnoj krvi bolesnika potrebno je i dalje pratiti četiri puta dnevno i prije spavanja jer se potreba za inzulinom može dodatno smanjivati ili se doza lijeka AMGLIDIA treba titrirati.
English: − in patients taking bosentan (see section 4.5)
Croatian: − u bolesnika s porfirijom; − u bolesnika koji uzimaju bosentan (vidjeti dio 4.5)
English: Do not use this medicine after the expiry date which is stated on the carton and bottle after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici iza oznake
English: The same child had a transient and minimal ASAT 73 IU/L, and ALAT 42 IU/L increased (normal range below 60 and 40 respectively).
Croatian: U istog djeteta došlo je do prolaznog i minimalnog povećanja ASAT 73 IU/l i ALAT 42 IU/l
English: Overdose of sulphonamides can result in hypoglycaemia.
Croatian: Predoziranje sulfonamidima može dovesti do hipoglikemije.
English: Cimetidine
Croatian: Cimetidin
English: Salicylates (such as aminosalicylic acid, para-aminosalicylic acid used for tuberculosis)
Croatian: Salicilati (na primjer aminosalicilatna kiselina, para-aminosalicilatna kiselina koja se koristi kod tuberkuloze)
English: Administration through a feeding tube should be avoided.
Croatian: Treba izbjegavati primjenu putem sonde za hranjenje.
English: The dose is measured by drawing the plunger of the syringe back until it reaches the marking for the dose the doctor has prescribed for your child.
Croatian: Doza se mjeri tako da se klip štrcaljke povuče do oznake doze koju je liječnik propisao Vašem djetetu.
English: Sulphonylureas like glibenclamide have been shown to be effective in certain genetic mutations responsible for the genesis of neonatal diabetes.
Croatian: Sulfonilureje kao što je glibenklamid pokazale su se djelotvornima za određene mutacije gena odgovorne za nastanak neonatalnog dijabetesa.
English: Coumarin derivatives (such as dicoumarol, acenocoumarol) used to decrease the clotting ability of the blood
Croatian: Derivati kumarina (kao što je dikumarol, acenokumarol) koji se upotrebljavaju za smanjenje sposobnosti zgrušavanja krvi
English: Slip about the first 1 cm of the syringe into the child's mouth and place it against the inside cheek; Let the child suck.
Croatian: Stavite otprilike 1 cm štrcaljke u usta djeteta i naslonite je uz unutrašnji dio obraza.
English: Make sure you have the box containing the syringe size prescribed by your doctor.
Croatian: Provjerite sadrži li vaše pakiranje veličinu štrcaljke koju je propisao vaš liječnik.
English: Transitory diarrhea Abdominal pain Vomiting Dyspepsia
Croatian: Prolazni proljev Abdominalna bol
English: A comparative study of relative bioavailability between two suspensions of glibenclamide oral suspensions (0.6 mg/mL and 6 mg/mL) and crushed glibenclamide tablets (Daonil 5 mg) showed that when glibenclamide oral suspensions were administered, peak plasma concentrations of glibenclamide are reached 0.5 hours earlier than that observed with the crushed Daonil tablet (median value after administration is 2.5 hours compared to 3 hours).
Croatian: Komparativno ispitivanje relativne bioraspoloživosti između dvije suspenzije glibenklamida za oralnu primjenu (0,6 mg/ml i 6 mg/ml) te zdrobljenih tableta glibenklamida (Daonil 5 mg) pokazalo je da su nakon primjene suspenzije glibenklamida za oralnu primjenu vršne koncentracije glibenklamida u plazmi dosegnute 0,5 sati ranije u usporedbi sa zdrobljenim tabletama Daonil (medijan vrijednosti nakon primjene iznosi 2,5 sati u odnosu na 3 sata).
English: Isoniazid used to treat tuberculosis
Croatian: Izoniazid koji se upotrebljava za liječenje tuberkuloze
English: The values for maximum plasma concentrations (Cmax) were similar for the two suspensions (201.71 ± 71.43 ng/mL for the 6 mg/mL suspension and 206.93 ± 67.33 ng/mL for the 0.6 mg/mL suspension).
Croatian: Vrijednosti maksimalnih koncentracija u plazmi (Cmax) bile su slične za obje suspenzije (201,71 ± 71,43 ng/ml za oralnu suspenziju od 6 mg/ml i
English: In repeated dose toxicity studies with oral administration of high doses of glibenclamide, effects on pancreatic beta-cells were observed (enlargement of the islets of Langerhans with irregularly configured islets and reduction in pancreatic β-cell granulation in rats at doses of ≥ 30 mg/kg/day, beta-cell exhaustion as indicated by depletion of insulin-containing granules in rabbits at doses of > 100 mg/kg/day).
Croatian: U ispitivanjima toksičnosti nakon ponovljene doze u pogledu oralne primjene visokih doza glibenklamida, primijećeni su učinci na beta stanice gušterače (povećanje Langerhansovih otočića s nepravilno konfiguriranim otočićima i smanjenjem granulacije beta stanica u gušterači štakora pri dozama ≥ 30 mg/kg/dan, iscrpljenost beta stanica na koje upućuje deplecija granula koje sadrže inzulin u kunića pri dozama > 100 mg/kg/dan)."
English: The 1 mL oral syringe is thin and small while the 5 mL syringe is thick and long.
Croatian: Štrcaljka za usta od 1 ml tanka je i mala, dok je štrcaljka od 5 ml debela i dugačka.
English: The median [IQR] dose of sulfonylurea fell over the follow-up with a median [IQR] dose of 0.30 mg/kg/day [0.14-0.53] mg/kg/day at one year and of 0.23 mg/kg/day [0.12-0.41 mg/kg/day] at 10 years, p=0.03).
Croatian: Medijan [IQR] doze sulfonilureje smanjio se tijekom praćenja s medijanom [IQR] doze od 0,30 mg/kg/dan [0,14 - 0,53 mg/kg/dan] nakon jedne godine i od 0,23 mg/kg/dan [0,120,41 mg/kg/dan] nakon 10 godina, p=0,03.
English: Oestrogens (such as 17-beta oestradiol) used for hormonal treatment
Croatian: Estrogeni (kao što je 17-beta estradiol) koji se upotrebljavaju za hormonsko liječenje
English: As shown in the literature and in the clinical studies performed with AMGLIDIA, the average daily dose is expected to be around 0.2 to 0.5 mg/kg/day in most of the patients suffering from neonatal diabetes.
Croatian: Kako se navodi u literaturi i kliničkim ispitivanjima s lijekom AMGLIDIA, očekuje se da je u većine bolesnika s neonatalnim dijabetesom prosječna dnevna doza oko 0,2 do 0,5 mg/kg/dan.
English: If there is major vomiting, a fast-acting insulin should be used to treat the patient until vomiting stops.
Croatian: Ako dolazi do velikog povraćanja, treba primijeniti inzulin s brzim djelovanjem dok bolesnik ne prestane povraćati.
English: Plasma clearance of glibenclamide may be prolonged in patients suffering from liver disease.
Croatian: Klirens glibenklamida iz plazme može se produljiti kod bolesnika s bolesti jetre.
English: Since no interaction study between glibenclamide and milk has been performed, and despite absence of food effect on glibenclamide absorption, recommendation is given to administer the suspension 15 minutes before child's milk feeding.
Croatian: Budući da nije provedeno ispitivanje u pogledu interakcije glibenklamida i mlijeka te unatoč tomu što nije primijećen učinak hrane na apsorpciju glibenklamida, preporučuje se primjena suspenzije 15
English: Glibenclamide, a second-generation, short half-life sulphonylurea, is a hypoglycaemic agent that reduces blood-glucose by stimulating insulin release by the pancreas; this effect depends on the presence of active beta-cells or beta-cells made active by glibenclamide in the pancreatic islets in certain cases of neonatal diabetes.
Croatian: Glibenklamid, sulfonilureja druge generacije kratkog poluvijeka jest hipoglikemijski lijek koji smanjuje glukozu u krvi stimuliranjem otpuštanja inzulina iz gušterače; taj učinak ovisi o prisutnosti aktivnih beta stanica ili beta stanica koje je aktivirao glibenklamid u Langerhansovim otočićima u određenim slučajevima neonatalnog dijabetesa.
English: Teeth problems (common: may affect up to 1 in 10 people): - Tooth discoloration.
Croatian: Problemi sa zubima (često: mogu se javiti u do 1 na 10 osoba): - promjena boje zubiju.
English: Potential effects
Croatian: Mogući efekti
English: The dose to be administered is obtained by drawing the plunger back as far as the scale marking for the dose determined for each child.
Croatian: Doza koja se primjenjuje dobiva se povlačenjem klipa do oznake doze propisane za svako dijete.
English: The most frequent adverse reactions are hypoglycemia, transitory diarrhea and abdominal pain.
Croatian: Najčešće nuspojave su hipoglikemija, prolazni proljev i bolovi u abdomenu.
English: If on insulin pump, reduce basal rate of insulin pump by 50% and reduce further in accordance with capillary blood-glucose measurements.
Croatian: Ako bolesnik koristi inzulinsku pumpu, smanjite bazalnu brzinu inzulinske pumpe za 50 % i dodatno je smanjujte u skladu s razinama glukoze u kapilarnoj krvi.
English: • The Amglidia 0.6 mg/mL strength should not be used for posology higher than 0.6 mg/kg/day to limit the exposure to the sodium benzoate excipient.
Croatian: • Lijek Amglidia jačine 0,6 mg/ml ne smije se koristiti za doze veće od 0,6 mg/kg/dan radi ograničavanja izloženosti natrijevu benzoatu koji je pomoćna tvar.
English: This medicine may only be used for the treatment of neonatal diabetes in newborns, infants and children.
Croatian: Ovaj lijek se može koristiti samo za liječenje neonatalnog dijabetesa u novorođenčadi, dojenčadi i djece.
English: Both acute and chronic alcohol intake, or excessive alcohol ingestion by people who drink occasionally, may attenuate the hypoglycaemic effect of glibenclamide or dangerously potentiate it by delaying its metabolic inactivation.
Croatian: Akutni i kronični unos alkohola, kao i unos pretjerane količine alkohola u osoba koje povremeno piju alkohol, može umanjiti hipoglikemijski učinak glibenklamida ili ga opasno potencirati odgađanjem metaboličke inaktivacije.
English: If your child carries a G6PD enzyme deficiency, he/she may experiment an abnormal breakdown of red blood cells (acute haemolytic anaemia) after taking AMGLIDIA.
Croatian: Ako Vaše dijete ima nedostatak enzima G6PD, nakon primjene lijeka AMGLIDIA može doći do abnormalnog razlaganja crvenih krvnih stanica (akutna hemolitička anemija).
English: If you stop giving AMGLIDIA
Croatian: Ako prestanete davati lijek AMGLIDIA
English: Medicines
Croatian: Lijekovi
English: Please read the posology and method of administration in the SmPC attached to this prescriber's guide.
Croatian: Pročitajte doziranje i način primjene u sažetku opisa svojstava lijeka priloženom ovom vodiču za propisivača.
English: - Other laboratory blood tests changes: increased levels of the white blood cells called eosinophils
Croatian: - druge promjene na laboratorijskim pretragama krvi: povećane razine bijelih krvnih stanica pod nazivom eozinofili (hipereozinofilija), blago do umjereno smanjenje krvnih pločica
English: After opening, keep the bottle tightly closed after each use and stored for a maximum of 30 days.
Croatian: Nakon otvaranja bočicu treba čvrsto zatvoriti nakon svake uporabe i čuvati najviše 30 dana.
English: Glucagon
Croatian: Glukagon
English: Glibenclamide crosses the placenta mostly in small amounts; however, transfer is highly variable among patients.
Croatian: Glibenklamid prolazi kroz posteljicu uglavnom u malim količinama, međutim, ta se količina uvelike razlikuje od bolesnice do bolesnice.
English: Turn the bottle with the syringe upside down (figure 3).
Croatian: Okrenite bočicu tako da štrcaljka bude okrenuta naopačke (slika 3).
English: Cyclophosphamides used to treat different types of cancer
Croatian: Ciklofosfamidi koji se upotrebljavaju za liječenje različitih vrsta raka
English: Breast-feeding seems to be compatible, but as a precautious measure monitoring of the fully breast-fed infant's blood sugar level is advisable.
Croatian: Čini se da je dojenje kompatibilno s primjenom ovog lijeka, ali kao mjera opreza preporučuje se praćenje razine šećera u krvi u dojenčadi koja su isključivo dojena.
English: In case of a partial response on lower doses, as shown by reduced insulin requirements, a further dose increase up to 2.8 mg/kg/day may be tried in selected cases.
Croatian: slučaju djelomičnog odgovora na niže doze, što se očituje u manjoj potrebi za inzulinom, u nekim je slučajevima moguće dodatno povećati dozu do 2,8 mg/kg/dan.
English: Since AMGLIDIA is administered with an oral syringe graduated in mL, the calculated daily dose should be expressed in mL by the physician explicitly stating the strength to be used.
Croatian: Budući da se lijek AMGLIDIA primjenjuje štrcaljkom za usta graduiranom na mililitre, izračunatu dnevnu dozu potrebno je izraziti u ml, pri čemu liječnik izričito navodi jačinu lijeka koja se treba primjenjivati.
English: Rare cases of agranulocytosis, hemolytic anemia, bone marrow aplasia and pancytopenia
Croatian: Rijetki slučajevi agranulocitoze, hemolitičke anemije, aplazije koštane srži i pancitopenije
English: Colesevelam binds to glibenclamide and reduces glibenclamide absorption from the gastrointestinal tract.
Croatian: Kolesevelam se veže za glibenklamid i smanjuje apsorpciju glibenklamida iz gastrointestinalnog trakta.
English: After first opening, use within 30 days.
Croatian: Upotrijebiti unutar 30 dana nakon prvog otvaranja.
English: Phenothiazine derivatives (such as chlorpromazine) used to treat schizophrenia and other psychoses
Croatian: Derivati fenotiazina (kao što je klorpromazin) koji se upotrebljavaju za liječenje shizofrenije i drugih psihoza