FrancophonIA/ELRC3.0 huggingface dataset:
English: Given the long half-life of Lutetium (177Lu) it is specially recommended to avoid internal contamination.
Slovenian: Glede na dolg razpolovni čas lutecija (177Lu) je še posebej priporočljivo, da se izognete notranji kontaminaciji.
English: Any unused product or waste material should be disposed of in accordance with local requirements.
Slovenian: Neuporabljen radionuklidni predhodnik ali odpadni material zavrzite v skladu z lokalnimi predpisi.
English: Their receipt, storage, use, transfer and disposal are subject to the regulations and/or appropriate licences of the competent official authorities.
Slovenian: Za njihovo sprejemanje, shranjevanje, uporabo, prenos in odstranjevanje veljajo predpisi in/ali ustrezna dovoljenja pristojnih organov.
English: When an administration of radioactive medicinal products to a woman of childbearing potential is intended, it is important to determine whether or not she is pregnant.
Slovenian: Kadar se načrtuje dajanje radiofarmakov ženski v rodni dobi, je pomembno ugotoviti, ali je ženska morda noseča.
English: No animal toxicity studies were conducted with Lumark.
Slovenian: Študij toksičnosti na živali z radionuklidnim predhodnikom Lumark niso izvedli.
English: In the absence of compatibility studies, this medicinal product must not be mixed with medicinal products other than the medicinal products to be radiolabelled.
Slovenian: Zaradi pomanjkanja študij kompatibilnosti tega radionuklidnega predhodnika ne smemo mešati z drugimi zdravili, razen z zdravili, namenjenimi za radioaktivno označevanje.
English: It is not known whether Lutetium (177Lu) chloride may interact with other medicines as specific studies have not been carried out.
Slovenian: Ni znano, ali lahko lutecijev (177Lu) klorid vpliva na druga zdravila, saj specifičnih študij niso izvedli.
English: Before administration of Lumark you should: drink plenty of water before being given the radiolabelled medicine in order to urinate as often as possible during the first few hours after the procedure.
Slovenian: - pijte veliko vode, preden vam dajo radiooznačeno zdravilo, da boste v prvih urah po postopku čim pogosteje urinirali.
English: Lu)-chloride.
Slovenian: (177Lu) klorid.
English: Lutetium (177Lu) has a half-life of 6.647 days.
Slovenian: Lutecij (177Lu) ima razpolovno dobo 6,647 dneva.
English: The minimal specific activity is 500 GBq/mg Lutetium (177Lu) at the ART.
Slovenian: Minimalna specifična aktivnost je 500 GBq/mg lutecija (177Lu) v ART.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu.
Slovenian: Podrobne informacije o radionuklidnem predhodniku so objavljene na spletni strani Evropske agencije za zdravila http://www.ema.europa.eu.
English: According to literature reports and taking a conservative approach (maximum patient dose of 10 GBq, average labeling yield and no additional measures), it may be considered that 177Lu-labelled medicinal products do not lead to reproductive toxicity including spermatogenetic damage in male testes or genetic damage in male testes or female ovaries.
Slovenian: Upoštevajoč poročila iz literature in konzervativni pristop (največji odmerek za bolnika 10 GBq, povprečen rezultat označevanja in odsotnost dodatnih ukrepov), lahko predpostavljamo, da z lutecijem (177Lu) označena zdravila ne vplivajo na sposobnost razmnoževanja, vključno z okvarami spermatogeneze v moških testisih in genetskimi okvarami moških testisov ali ženskih jajčnikov.
English: Intraperitoneal administration resulted in generalized peritonitis with adhesion and accumulation of some ascetic fluid.
Slovenian: Intraperitonealno dajanje je povzročilo generalizirani peritonitis z adhezijo in kopičenjem ascitesa.
English: • Carcinoid crisis
Slovenian: Neznana: karcinoidna kriza
English: Due to the capacity of the chelating ligands (DTPA, EDTA) of forming water soluble complexes, the complexes and bound Lutetium(177Lu) are rapidly eliminated by the kidneys.
Slovenian: Na podlagi zmožnosti kelatnih ligandov (DTPA, EDTA), da tvorijo v vodi topne komplekse, se kompleksi in vezani lutecij (177Lu) hitro izločijo prek ledvic.
English: Medicines radiolabelled with Lumark will only be used in special, controlled areas.
Slovenian: radiooznačena z radionuklidnim predhodnikom Lumark, bodo uporabljena le v posebnih, nadzorovanih okoljih.
English: Activity Reference Time (ART): {DD/MM/YYYY} {hh:mm} CET Specific activity (at ART): {YY} GBq/mg Lu mass:
Slovenian: Referenčni čas aktivnosti (ART): {DD/MM/LLLL} {uu:mm} CET Specifična aktivnost (v ART): {YY} GBq/mg
English: For administration after in vitro radiolabelling.
Slovenian: Za dajanje po radiooznačevanju in vitro.
English: Before administering radiopharmaceuticals to a mother who is breast-feeding, consideration should be given to the possibility of delaying the administration of radionuclide until the mother has ceased breast-feeding, and to what is the most appropriate choice of radiopharmaceuticals, bearing in mind the secretion of activity in breast milk.
Slovenian: Pred uporabo radiofarmakov pri doječi materi je treba razmisliti o odložitvi uporabe radionuklida, dokler mati ne neha dojiti, in o najustreznejši izbiri radiofarmakov, pri čemer je treba upoštevati izločanje aktivnosti sevanja v materino mleko.
English: 5111 PV Baarle-Nassau NETHERLANDS
Slovenian: 5111 PV Baarle-Nassau Nizozemska
English: Administration of a high activity (7.400 MBq) of the Lutetium(177Lu)-labelled medicinal product results in an average radiation dose rate at 1 m distance from the patient of 4-11 µSv/h after 24 hours.
Slovenian: Dajanje zdravil, ki so označena z lutecijem (177Lu) visoke aktivnosti (7,400 MBq), povzroči povprečno stopnjo odmerkov sevanja 4-11 µSv/h na razdalji 1 m od bolnika po 24 urah.
English: By intraperitoneal route, the LD50 is approximately 300 mg/kg in mice and rats.
Slovenian: Z uporabo intraperitonealne poti znaša LD50 pri miših in podganah približno 300 mg/kg.
English: (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000),
Slovenian: Neželeni učinki so razdeljeni v skupine po pogostnostih po MedDRA: zelo pogosti (≥1/10), pogosti (≥1/100 do <1/10), občasni (≥1/1.000 do <1/100), redki (≥1/10.000 do <1/1.000), zelo redki (<1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: Only syringe needles (for example non-metallic) with proven resistance to dilute acid should be used to minimize trace metal impurity levels.
Slovenian: Uporabljajo se lahko samo igle za brizge (na primer nekovinske) z dokazano odpornostjo proti razredčenim kislinam, da se zmanjša raven nečistot v obliki kovin v sledovih.
English: For instructions on extemporary preparation of the medicinal product before administration, see section 12.
Slovenian: Za navodila glede vnaprejšnje priprave zdravila pred dajanjem glejte poglavje 12.
English: The studies suggest that the intravenous toxicity of the ionic compounds of the rare earth elements would decrease with atomic weight resulting in Lutetium (177Lu) being the least toxic of the series.
Slovenian: Študije kažejo, da intravenska toksičnost ionskih spojin redkih zemeljskih elementov upada z atomsko težo, zaradi česar je lutecij (177Lu) med njimi najmanj toksičen.
English: SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF APPROPRIATE Any unused product or waste material should be disposed of in accordance with local requirements.
Slovenian: POSEBNI VARNOSTNI UKREPI ZA ODSTRANJEVANJE NEUPORABLJENIH ZDRAVIL ALI IZ NJIH NASTALIH ODPADNIH SNOVI, KADAR SO POTREBNI
English: Like all medicines, the medicine radiolabelled with Lumark can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo, radiooznačeno z radionuklidnim predhodnikom Lumark, neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: By intravenous route, the LD50 in rats and mice ranges between 30 and 60 mg/kg.
Slovenian: Z uporabo intravenske poti LD50 pri podganah in miših obsega med 30 in 60 mg/kg.
English: The complete Summary of Product Characteristics (SmPC) of Lumark is provided as a separate document in the pack of the medicinal product, with the objective to provide healthcare professionals with other additional scientific and practical information about the use of this product.
Slovenian: Celotni povzetek glavnih značilnosti zdravila za radionuklidni predhodnik Lumark je na voljo kot ločen dokument v pakiranju radionuklidnega predhodnika z namenom omogočiti zdravstvenim delavcem še druge, dodatne, znanstvene in praktične informacije o uporabi tega radionuklidnega predhodnika.
English: Each pack contains one vial in a lead container.
Slovenian: Eno pakiranje vsebuje eno vialo v svinčenem vsebniku.
English: Uncommon (may affect up to 1 in 100 people): • Bone marrow cancer (acute myeloid leukaemia)
Slovenian: Občasni (pojavijo se lahko pri največ 1 od 100 bolnikov): − rak kostnega mozga (akutna mieloična levkemija)
English: After the medicine radiolabelled with Lumark is administered, it will deliver certain amounts of ionising radiation (radioactivity) which carries a small risk of cancer and development of hereditary defects.
Slovenian: Ko boste prejeli zdravilo, radiooznačeno z radionuklidnim predhodnikom Lumark, boste prejeli določene količine ionizirajočega sevanja (radioaktivnosti), ki prinaša majhno tveganje za raka in razvoj dednih okvar.
English: Other medicines and medicines radiolabelled with Lumark Tell your nuclear medicine doctor if you are taking, have recently taken or might take any other medicines since they may interfere with the procedure.
Slovenian: Druga zdravila in zdravila, radiooznačena z radionuklidnim predhodnikom Lumark Obvestite zdravnika nuklearne medicine, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo, saj bi ta zdravila lahko vplivala na postopek.
English: The vials are placed in a lead container for protective shielding and packed in a plastic jar.
Slovenian: Viale so v svinčenem vsebniku, ki predstavlja varovalni ščit, in so pakirane v plastičnem lončku.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your nuclear medicine doctor for advice before you are given medicines radiolabelled with Lumark.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom nuklearne medicine, preden vam dajo zdravilo, radiooznačeno z radionuklidnim predhodnikom Lumark.
English: If you have been given more medicine radiolabelled with Lumark than you should Since the medicine radiolabelled with Lumark is handled by a nuclear medicine doctor under strictly controlled conditions, there is only a very small chance of possible overdose.
Slovenian: Če ste prejeli več zdravila, radiooznačenega z radionuklidnim predhodnikom Lumark, kot bi smeli Ker z zdravilom, radiooznačenim z radionuklidnim predhodnikom Lumark, rokuje zdravnik nuklearne medicine v strogo nadzorovanih pogojih, je verjetnost prevelikega odmerjanja zelo majhna.
English: This medicinal must be used only for the radiolabelling of carrier molecules, which have been specifically developed and authorised for radiolabelling with this radionuclide.
Slovenian: Uporablja se samo za radioaktivno označevanje nosilnih molekul, ki so bile specifično razvite in odobrene za radioaktivno označevanje s tem radionuklidom.
English: When in doubt, it is important to consult your nuclear medicine doctor.
Slovenian: Če ste v dvomih, je pomembno, da se posvetujte z zdravnikom nuklearne medicine.
English: Gallbladder Wall LLI Wall Small Intestine Stomach Wall ULI Wall Heart Wall Kidneys
Slovenian: nadledvične žleze možgani prsa stena žolčnega mehurja stena spodnjega dela debelega črevesa tanko črevo želodčna stena stena zgornjega dela debelega črevesa srčna stena ledvice jetra pljuča mišice jajčniki trebušna slinavka rdeči kostni mozeg osteogene celice koža vranica testisi priželjc ščitnica stena sečnega mehurja maternica Celotno telo
English: Pharmacokinetics of Lutetium (177Lu) was investigated in rats and mice.
Slovenian: Farmakokinetiko lutecija (177Lu) so proučevali pri podganah in miših.
English: Pregnancy The use of Lutetium (177Lu)-labelled medicinal products is contraindicated during established or suspected pregnancy or when pregnancy has not been excluded (see section 4.3).
Slovenian: Nosečnost Uporaba z lutecijem (177Lu) označenih zdravil je kontraindicirana med ugotovljeno nosečnostjo ali sumom nanjo oziroma kadar nosečnosti ni mogoče izključiti (glejte poglavje 4.3).
English: Lumark is not intended for direct use in patients.
Slovenian: Radionuklidni predhodnik Lumark ni namenjen za neposredno uporabo pri bolnikih.
English: If you are pregnant Medicines radiolabelled with Lumark must not be administered if you are pregnant.
Slovenian: Če ste noseči Zdravil, radiooznačenih z radionuklidnim predhodnikom Lumark, ne smete prejemati, če ste noseči.
English: Each vial contains a volume varying from 0.1 to 5 mL corresponding to an activity ranging from 8 to 400 GBq (at ART).
Slovenian: Ena viala vsebuje prostornino od 0,1 do 5 ml, kar ustreza aktivnosti, ki obsega od 8 do 400 GBq (v ART).
English: In all cases, the risk of the radiation is outweighed by the potential benefit of receiving the radiolabelled medicine.
Slovenian: V vseh primerih možne koristi zaradi prejema radiooznačenega zdravila odtehtajo tveganje sevanja.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja radionuklidnega predhodnika je le s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: Healthcare personnel are advised to limit the time of close contact with patients injected with Lutetium (177Lu)-radiopharmaceuticals.
Slovenian: Zdravstvenemu osebju je treba svetovati, naj omeji čas tesnega stika z bolniki, ki so prejeli injekcije radiofarmakov z lutecijem (177Lu).
English: The nuclear medicine doctor supervising the procedure will decide on the quantity of medicine radiolabelled with Lumark to be used in your case.
Slovenian: Zdravnik nuklearne medicine, ki bo nadzoroval postopek, bo določil količino radionuklidnega predhodnika Lumark, ki bo uporabljena pri vas.
English: The toxicity of Lutetium (177Lu) chloride has been studied in different mammals and using different administration routes.
Slovenian: Toksičnost lutecijevega (177Lu) klorida so proučevali pri različnih sesalcih in z uporabo različnih poti dajanja.
English: Storing Lumark is the responsibility of the specialist and will be done in appropriate premises.
Slovenian: Za shranjevanje radionuklidnega predhodnika Lumark je odgovoren specialist, ki ga izvede v ustreznih prostorih.
English: Radiolabelling of carrier molecules, such as monoclonal antibodies, peptides or other substrates, with Lutetium (177Lu) chloride is very sensitive to the presence of trace metal impurities.
Slovenian: Radioaktivno označevanje nosilnih molekul, kot so monoklonska protitelesa, peptidi ali drugi substrati, z lutecijevim (177Lu) kloridom je zelo občutljivo na prisotnost nečistot v obliki kovin v sledovih.
English: Radiopharmaceuticals should be received, used and administered only by authorised persons in designated clinical settings.
Slovenian: Radiofarmake sme sprejemati, uporabljati in dajati samo pooblaščeno osebje v izbranih kliničnih ustanovah.
English: Radioactive medicinal products should be prepared by the user in a manner which satisfies both radiation safety and pharmaceutical quality requirements.
Slovenian: Radiofarmake mora uporabnik pripraviti na način, ki bo zadostil zahtevam glede zaščite pred sevanjem in zahtevam farmacevtske kakovosti.
English: • a reduced number of white blood cells (leukopenia, lymphopenia or neutropenia) which are important for protecting the body against infection
Slovenian: - zmanjšanega števila rdečih krvnih celic (anemije); - zmanjšanega števila krvnih ploščic v krvi (trombocitopenija), ki so pomembne za zaustavitev krvavitve; - zmanjšanega števila belih krvnih celic (levkopenija, limfopenija ali nevtropenija), ki so pomembne za zaščito telesa pred okužbo.
English: Pharmacokinetic data on Lumark related to free Lutetium:
Slovenian: Farmakokinetični podatki o radionuklidnem predhodniku Lumark, povezani s prostim lutecijem:
English: LIST OF EXCIPIENTS Hydrochloric acid Water for injections
Slovenian: SEZNAM POMOŽNIH SNOVI klorovodikova kislina voda za injekcije
English: What Lumark is and what it is used for
Slovenian: Kaj je radionuklidni predhodnik Lumark in za kaj ga uporabljamo
English: When the precursor is bound to a carrier molecule the content of radioactive free Lutetium (177Lu) is supposed to be less than the stated amounts depending on the carrier used.
Slovenian: Ko se predhodnik veže na nosilno molekulo, naj bi vsebnost radioaktivnega prostega lutecija (177Lu) znašala manj od navedenih količin, glede na uporabljeno nosilno molekulo.
English: What you need to know before the medicine radiolabelled with Lumark is used The medicine radiolabelled with Lumark must not be used: - if you are allergic to Lutetium or any of the other ingredients of this medicine (listed in section 6).
Slovenian: Kaj morate vedeti, preden vam bodo dali zdravilo, radiooznačeno z zdravilom Lumark Zdravilo, radiooznačeno z radionuklidnim predhodnikom Lumark, se pri vas ne sme uporabiti: - če ste alergični na lutecij ali katero koli sestavino tega zdravila (navedeno v poglavju 6); - če ste noseči ali menite, da bi lahko bili noseči.
English: Description of selected adverse reactions:
Slovenian: Opis izbranih neželenih učinkov
English: - The other ingredients are hydrochloric acid and water for injections.
Slovenian: - Drugi sestavini radionuklidnega predhodnika sta klorovodikova kislina in voda za injekcije.
English: The possible use of chelating therapies could interfere with the use of Lutetium(177Lu)-labeled medicinal products.
Slovenian: Morebitna uporaba kelacijskih zdravljenj bi lahko vplivala na uporabo z lutecijem (177Lu) označenih zdravil.
English: Blood and lymphatic system disorders very common: Anaemia, thrombocytopenia, leukopenia and lymphopenia
Slovenian: Zelo pogosti: anemija, trombocitopenija, levkopenija in limfopenija
English: The toxicity of the free Lutetium (177Lu) due to in vivo release from the labelled biomolecule in the body during therapy could be reduced by post-administration of chelating agents.
Slovenian: Toksičnost prostega lutecija (177Lu) zaradi sproščanja in vivo iz označene biomolekule v telesu med zdravljenjem je mogoče zmanjšati z naknadnim dajanjem kelatorjev.
English: For this reason it is mandatory to use protective high quality (latex/nitrile) gloves in any direct contact with the radiopharmaceutical (vial/syringe) and with the patient.
Slovenian: (lateks/nitril) pri vsakem neposrednem stiku z radiofarmakom (viala/brizga) in z bolnikom.
English: Should you have any further question on the use of Lumark, please ask the nuclear medicine doctor who supervises the procedure.
Slovenian: Če imate kakršna koli dodatna vprašanja o uporabi radionuklidnega predhodnika Lumark, se posvetujte z zdravnikom nuklearne medicine, ki nadzoruje postopek.
English: What Lumark looks like and contents of the pack Lumark is presented as a sterile, clear, and colourless solution in a colourless type I glass vial of 10 mL, closed with a bromobutylrubber stopper and aluminium overseal
Slovenian: Izgled radionuklidnega predhodnika Lumark in vsebina pakiranja Radionuklidni predhodnik Lumark je sterilna, prosojna in brezbarvna raztopina v brezbarvni viali iz stekla tipa I in s prostornino 10 ml, ki je zaprta z zaporko iz bromobutilne gume in z aluminijastim pokrovčkom.
English: After neuroendocrine tumours are treated with Lutetium (177Lu), patients may experience symptoms associated with release of hormones from the tumour cells, known as carcinoid crisis.
Slovenian: Po zdravljenju nevroendokrinih tumorjev z lutecijem (177Lu) lahko bolniki doživijo simptome, povezane s sproščanjem hormonov iz tumorskih celic, kar imenujemo karcinoidna kriza.
English: Lumark is only used to radiolabel medicines that have been specifically developed for use with the active substance lutetium (177Lu)chloride.
Slovenian: Lumark se uporablja le za radiooznačevanje zdravil, ki so bila posebej razvita za uporabo z zdravilno učinkovino lutecijevim (177Lu) kloridom.
English: Each pack contains 1 glass vial in a lead cannister placed in a plastic jar.
Slovenian: Eno pakiranje vsebuje eno stekleno vialo v svinčenem vsebniku, ki je vložen v plastičen lonček.
English: Lot:
Slovenian: Masa Lu:
English: • Tumour lysis syndrome (rapid breakdown of tumour cells)
Slovenian: − karcinoidna kriza − sindrom tumorske lize (hitra razgradnja tumorskih celic)
English: Lutetium (177Lu) is produced by neutron irradiation of enriched Lutetium (176Lu).
Slovenian: Lutecij (177Lu) se izdeluje z nevtronskim obsevanjem obogatenega lutecija (176Lu).
English: The use of Lutetium (177Lu)-labelled medicines does involve exposure to small amounts of radioactivity.
Slovenian: Uporaba zdravil, označenih z lutecijem (177Lu), vključuje izpostavljenost manjšim količinam radioaktivnosti.
English: Your nuclear medicine doctor will inform you about the usual duration of the procedure after the administration of the medicine radiolabelled with Lumark.
Slovenian: Zdravnik nuklearne medicine vas bo obvestil o običajnem trajanju postopka po dajanju zdravila, radiooznačenega z radionuklidnim predhodnikom Lumark.
English: After administration of the medicine radiolabelled with Lumark has been performed The nuclear medicine doctor will inform you if you need to take any special precautions after receiving the medicine radiolabelled with Lumark.
Slovenian: Po končanem dajanju zdravila, radiooznačenega z radionuklidnim predhodnikom Lumark Zdravnik nuklearne medicine vas bo obvestil, ali morate po prejemu zdravila, radiooznačenega z radionuklidnim predhodnikom Lumark, uporabljati kakršne koli posebne previdnostne ukrepe.
English: Grounds for the variation to the terms of the marketing authorisation(s) On the basis of the scientific conclusions for Lutetium (177Lu) chloride the CHMP is of the opinion that the benefit-risk balance of the medicinal product(s) containing Lutetium (177Lu) chloride is unchanged subject to the proposed changes to the product information.
Slovenian: Na podlagi znanstvenih zaključkov za lutecijev (177Lu) klorid odbor CHMP meni, da je razmerje med koristjo in tveganjem zdravil(-a), ki vsebuje(-jo) lutecijev (177Lu) klorid nespremenjeno ob upoštevanju predlaganih sprememb v informacijah o zdravilu.
English: How to use the medicine radiolabelled with Lumark
Slovenian: Kako se uporablja zdravilo, radiooznačeno z zdravilom Lumark
English: Read all of this leaflet carefully before you are given the medicine combined with Lumark because it contains important information for you.
Slovenian: Pred začetkom jemanja zdravila, kombiniranega z radionuklidnim predhodnikom Lumark, natančno preberite navodilo, ker vsebuje za vas pomembne podatke!
English: Lumark should not be administered directly to the patient.
Slovenian: Radionuklidni predhodnik Lumark se ne sme dajati neposredno bolniku.
English: The dosimetry table below is presented in order to evaluate the contribution of non-conjugated Lutetium(177Lu) to the radiation dose following the administration of Lutetium (177Lu)-labelled medicinal product or resulting from an accidental intravenous injection of Lumark.
Slovenian: Spodnja preglednica dozimetrije predstavlja ocenjevanje prispevka nekonjugiranega lutecija (177Lu) k odmerku sevanja, ki sledi dajanju z lutecijem (177Lu) označenega zdravila ali je rezultat neželenega intravenskega injiciranja radionuklidnega predhodnika Lumark.