FrancophonIA/ELRC3.0 huggingface dataset:
English: What benefits of Dovato have been shown in studies?
Danish: Hvilke fordele viser studierne, at der er ved Dovato?
English: How is Dovato used?
Danish: Hvordan anvendes Dovato?
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Dovato have been included in the summary of product characteristics and the package leaflet.
Danish: Der er anført anbefalinger og forholdsregler i produktresuméet og indlægssedlen, som patienter og sundhedspersonale skal følge for at sikre risikofri og effektiv anvendelse af Dovato.
English: Furthermore, both active substances are available in a single tablet and are acceptably safe.The European Medicines Agency therefore decided that Dovato's benefits are greater than its risks and that it can be authorised for use in the EU.
Danish: Det Europæiske Lægemiddelagentur konkluderede derfor, at fordelene ved Dovato opvejer risiciene, og at det kan godkendes til anvendelse i EU.
English: How does Dovato work?
Danish: Hvordan virker Dovato?
English: 3 (3x1) inhalers (360(3x120) actuations) (multipack)
Danish: 3 (3x1) inhalatorer (360(3x120) pust) (multipakning)
English: 1 inhaler (120 actuations)
Danish: 1 inhalator (120 pust)
English: Pack size
Danish: EU-nummer
English: Strength Pharmaceutical Form
Danish: (Særnavn) Navn Styrke Lægemiddelform Administration Emballage Pakningsstørrelse EU/1/16/1152/001 Roteas
English: • Not known (frequency cannot be estimated from the available data)
Danish: • Ikke kendt (kan ikke estimeres ud fra forhåndenværende data)
English: There was a significant and beneficial effect in quality of life (as assessed by PD-QUALIF scale).
Danish: Der var en signifikant og gavnlig effekt på livskvaliteten (målt på PD-QUALIF skalaen).
English: 597 678 01 Blansko Czech Republic
Danish: 597 678 01 Blansko Tjekkiet
English: The frequency of possible side effects listed below is defined using the following convention:
Danish: Hyppigheden af mulige bivirkninger er anført nedenfor i henhold til følgende konvention:
English: Take the next dose normally, when it is time to take it.
Danish: Tag den næste dosis på det tidspunkt, hvor De normalt ville gøre det.
English: Your doctor may need to adjust or stop your dose.
Danish: Lægen kan være nødt til at ændre Deres dosis eller stoppe behandlingen.
English: Less than 1% of rasagiline is excreted as unchanged product in urine.
Danish: Mindre end 1% rasagilin udskilles som uændret stof i urinen.
English: • abnormal dreams
Danish: • Unormale drømme
English: Patients should be regularly monitored for the development of impulse control disorders.
Danish: Patienterne bør regelmæssigt kontrolleres for udvikling af impulskontrolforstyrrelser.
English: It can be used together with or without levodopa (another medicine that is used to treat Parkinson's disease).
Danish: Det kan bruges sammen med eller uden levodopa (et andet lægemiddel, som anvendes til behandling af Parkinsons sygdom).
English: In case of overdose, patients should be monitored and the appropriate symptomatic and supportive therapy instituted.
Danish: I tilfælde af overdosering bør patienten overvåges, og passende symptomatisk og understøttende behandling iværksættes.
English: The absolute bioavailability of a single rasagiline dose is about 36%.
Danish: Den absolutte biotilgængelighed af en enkelt dosis rasagilin er ca. 36%.
English: Parkinson's disease is associated with symptoms of hallucinations and confusion.
Danish: Parkinsons sygdom er forbundet med symptomer som hallucinationer og forvirring.
English: The robustness of the results for the primary efficacy end point, was confirmed in a battery of additional statistical models and was demonstrated in three cohorts (ITT, per protocol and completers).
Danish: Resultaternes styrke for det primære effektmåls vedkommende blev bekræftet af en ekstra række statistiske modeller og blev påvist i tre kohorter (ITT, pr. protokol og gennemførende deltagere).
English: Any suspicious skin lesion should be evaluated by a specialist.
Danish: Enhver mistænkelig hudforandring bør vurderes af en speciallæge.
English: Rasagiline is rapidly absorbed, reaching peak plasma concentration (Cmax) in approximately 0.5 hours.
Danish: Rasagilin absorberes hurtigt og når peak plasmakoncentration (Cmax) efter ca. 0,5 timer.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking any medicine.
Danish: Hvis De er gravid eller ammer, har mistanke om, at De er gravid, eller planlægger at blive gravid, skal De spørge Deres læge eller apotekspersonalet til råds, før De tager nogen form for medicin.
English: Adverse events were mild or moderate and not related to rasagiline treatment.
Danish: Bivirkningerne var milde eller moderate og ikke relaterede til rasagilin behandlingen.
English: Children and adolescents Rasagiline Mylan is not recommended for use under the age of 18.
Danish: Børn og unge Rasagilin Mylan anbefales ikke til unge under 18 år.
English: Elderly No change in dose is required for elderly patients.
Danish: Dosisjustering er ikke nødvendig hos ældre patienter.
English: Rasagiline is not recommended for use in children and adolescents due to lack of data on safety and efficacy.
Danish: Rasagilin bør ikke anvendes til børn og unge pga. manglende dokumentation for sikkerhed og virkning.
English: In this study, the primary measure of efficacy was the change from baseline in the total score of the Unified Parkinson's Disease Rating Scale (UPDRS, parts I-III).
Danish: I denne undersøgelse var det primære effektmål ændringen fra baseline i total score på Unified Parkinson's Disease Rating Scale (UPDRS, del I-III).
English: With Parkinson's disease, there is a loss of cells that produce dopamine in the brain.
Danish: Parkinsons sygdom forårsager et tab af celler, som producerer dopamin i hjernen.
English: Preclinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated-dose toxicity and reproduction toxicity.
Danish: De prækliniske data viser ingen særlig risiko for mennesker vurderet ud fra konventionelle undersøgelser af sikkerhedsfarmakologi, toksicitet efter gentagne doser og reproduktionstoksicitet.
English: CARTON FOR BLISTER PACK
Danish: ÆSKE TIL BLISTERPAKNING
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached
Danish: • På anmodning fra Det Europæiske Lægemiddelagentur Når risikostyringssystemet ændres, særlig som følge af, at der er modtaget nye oplysninger, der kan medføre en væsentlig ændring i risk/benefit-forholdet, eller som følge af, at en vigtig milepæl (lægemiddelovervågning eller risikominimering) er nået.
English: There was also a statistically significant improvement over placebo with the rasagiline 0.5 mg group, yet the magnitude of improvement was lower.
Danish: Der sås også en statistisk signifikant forbedring i forhold til placebo i rasagilin 0,5 mg gruppen, men forbedringen var mindre.
English: Rasagiline did not present genotoxic potential in vivo and in several in vitro systems using bacteria or hepatocytes.
Danish: Rasagilin fremviste ikke genotoksisk potentiale in vivo eller i adskillige in vitro systemer med bakterier eller hepatocyter.
English: In addition, skin cancer was reported in around 1% of patients in the placebo controlled clinical trials.
Danish: Desuden observeredes hudcancer hos ca. 1% af patienterne, der deltog i placebokontrollerede, kliniske undersøgelser.
English: The following side effects have been reported in placebo controlled clinical trials:
Danish: Følgende bivirkninger er observeret i placebokontrollerede, kliniske undersøgelser:
English: Rasagiline Mylan is used for the treatment of Parkinson's disease.
Danish: Rasagilin Mylan anvendes til behandling af Parkinsons sygdom.
English: There are a number of known interactions between non-selective MAO inhibitors and other medicinal products.
Danish: Der er flere kendte interaktioner mellem ikke-selektive MAO-hæmmere og andre lægemidler.
English: Rasagiline is administered orally, at a dose of 1 mg once daily with or without levodopa.
Danish: Rasagilin indtages peroralt i en dosis på 1 mg én gang dagligt med eller uden levodopa.
English: Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system listed in Appendix V.
Danish: Læger og sundhedspersonale anmodes om at indberette alle formodede bivirkninger via det nationale rapporteringssystem anført i: Appendiks V.
English: Patients should be cautioned about operating hazardous machines, including motor vehicles, until they are reasonably certain that Rasagiline does not affect them adversely.
Danish: Patienter bør tilrådes forsigtighed ved betjening af maskiner, herunder også bilkørsel eller motorcykelkørsel, indtil de er forholdsvis sikre på, at rasagilin ikke påvirker dem ugunstigt.
English: Animals studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3).
Danish: Dyreforsøg indikerer ikke direkte eller indirekte skadelige virkninger på drægtighed, embryoets/fostrets udvikling, fødslen eller den postnatale udvikling (se pkt.
English: • chest pain (angina pectoris)
Danish: • Smerter i brystet (angina pectoris)
English: In both studies, the primary measure of efficacy was the change from baseline to treatment period in the mean number of hours that were spent in the “OFF” state during the day (determined from “24-hour” home diaries completed for 3 days prior to each of the assessment visits).
Danish: I begge undersøgelser var det primære effektmål ændringen fra baseline til behandlingsperiodens afslutning målt som det gennemsnitlige antal timer i ”off-periode” (bestemt ud fra ”24-timers” dagbøger udfyldt i hjemmet i 3 dage inden hvert kontrolbesøg).
English: Rasagiline Mylan helps to increase and sustain levels of dopamine in the brain.
Danish: Rasagilin Mylan er med til at øge og opretholde dopaminniveauet i hjernen.
English: Blister packs of 7, 10, 28, 30, 100 or 112 tablets PVC/PVDC/Al.
Danish: blisterpakninger med 7, 10, 28, 30, 100 eller 112 tabletter PVC/PVDC/Al.
English: Adverse reactions are ranked under headings of frequency using the following conventions: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000).
Danish: Bivirkningerne er opdelt efter hyppighed med følgende betegnelser: Meget almindelig (≥1/10), almindelig (≥1/100 til <1/10), ikke almindelig (≥1/1.000 til <1/100), sjælden (≥1/10.000 til <1/1.000), meget sjælden (<1/10.000).
English: These are called impulse control disorders.
Danish: Disse handlinger kaldes impulskontrolforstyrrelser.
English: These symptoms may resemble those observed with non-selective MAO inhibitors.
Danish: Disse symptomer kan ligne dem, der blev observeret under behandling med non-selektive MAO-hæmmere.
English: 1-Aminoindan is an active major metabolite and it is not a MAO-B inhibitor.
Danish: l-Aminoindan er en aktiv hovedmetabolit og ikke en MAO-B-hæmmer.
English: C/ Castelló no1, Pol. Las Salinas 08830, Sant Boi de Llobregat, Barcelona Spain
Danish: C/ Castelló no1, Pol. Las Salinas 08830, Sant Boi de Llobregat, Barcelona Spanien
English: Patients with Parkinson's disease are particularly vulnerable to the adverse effects of hypotension due to existing gait issues.
Danish: Patienter med Parkinsons sygdom er særligt sårbare over for hypotension på grund af deres eksisterende gangforstyrrelser.
English: Tell your doctor if you or your family/carer notices that you are developing unusual behaviours where you cannot resist the impulse, urges or cravings to carry out certain harmful or detrimental activities to yourself or others.
Danish: Fortæl det til lægen, hvis De eller Deres familie/omsorgsperson bemærker, at De er ved at udvikle en usædvanlig adfærd, hvor De ikke kan modstå lysten, fristelsen eller trangen til at udføre bestemte handlinger, der er uønskede eller skadelige for Dem selv eller andre.
English: Do not use this medicine after the expiry date which is stated on the carton or blister after EXP.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på æsken eller blisterpakningen efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: The metabolism of rasagiline proceeds through two main pathways: N-dealkylation and/or hydroxylation to yield: 1-Aminoindan, 3-hydroxy-N-propargyl-1 aminoindan and 3-hydroxy-1-aminoindan.
Danish: Metaboliseringen af rasagilin sker via to hovedmetaboliseringsveje: N-dealkylation og/eller hydroxylering til 1Aminoindan, 3-hydroxy-N-propargyl-1 aminoindan og 3-hydroxy-1-aminoindan.
English: The elevated dopamine level and subsequent increased dopaminergic activity are likely to mediate rasagiline's beneficial effects seen in models of dopaminergic motor dysfunction.
Danish: Det forhøjede dopaminniveau og den efterfølgende øgede dopaminerge aktivitet er sandsynligvis årsagen til rasagilins gavnlige virkning, som er set i modeller af dopaminerg motorisk dysfunktion.
English: There have been cases of patients who, while taking one or more medications for the treatment of Parkinson's disease, were unable to resist the impulse, drive or temptation to perform an action that could be harmful to themselves or others.
Danish: Der har været rapporter om patienter, som under behandling med et eller flere lægemidler mod Parkinsons sygdom har været ude af stand til at modstå lysten, trangen eller fristelsen til at udføre en handling, der kan være skadelig for dem selv eller andre.
English: No studies on the effects on the ability to drive and use machines have been performed.
Danish: Der er ikke foretaget undersøgelser af virkningen på evnen til at køre bil eller betjene maskiner.
English: During the clinical development program, the occurrence of cases of melanoma prompted the consideration of a possible association with rasagiline.
Danish: Under det kliniske udviklingsprogram gav forekomsten af melanomtilfælde anledning til overvejelser om, hvorvidt der var en mulig sammenhæng med anvendelsen af rasagilin.
English: Concomitant administration of rasagiline and entacapone increased rasagiline oral clearance by 28%.
Danish: Samtidig indtagelse af rasagilin og entakapon øgede den orale clearance af rasagilin med 28%.
English: Starch, pregelatinised maize Talc
Danish: Stivelse, prægelatiniseret majs Talkum
English: Decreasing the dose of levodopa may ameliorate this side effect.
Danish: Dosisreduktion af levodopa kan reducere denne bivirkning.
English: In the rasagiline clinical program overall, 1,361 patients were treated with rasagiline for 3,076.4 patient years.
Danish: I kliniske undersøgelser med rasagilin blev i alt 1.361 patienter behandlet med rasagilin i 3.076,4 patientår.
English: Synthon Hispania S.L., C/ Castelló no1, Pol. Las Salinas, 08830, Sant Boi de Llobregat, Barcelona, Spain
Danish: Synthon Hispania S.L., C/ Castelló no1, Pol. Las Salinas, 08830, Sant Boi de Llobregat, Barcelona, Spanien
English: Food does not affect the Tmax of rasagiline, although Cmax and exposure (AUC) are decreased by approximately 60% and 20%, respectively, when the medicinal product is taken with a high fat meal.
Danish: Føde påvirker ikke rasagilins Tmax, selv om Cmax og AUC falder med hhv. ca. 60% og 20%, når lægemidlet indtages sammen med et måltid med højt fedtindhold.
English: Since rasagiline potentiates the effects of levodopa, the adverse effects of levodopa may be increased and pre-existing dyskinesia exacerbated.
Danish: Eftersom rasagilin forstærker virkningen af levodopa, kan levodopas bivirkninger øges og allerede eksisterende dyskinesi forværres.
English: Because AUC is not substantially affected, rasagiline can be administered with or without food.
Danish: Eftersom AUC ikke påvirkes væsentligt, kan rasagilin indtages uafhængigt af måltider.
English: There have been reports of hypotensive effects when rasagiline is taken concomitantly with levodopa.
Danish: Der har været tilfælde af hypotensive bivirkninger, hvis rasagilin tages samtidig med levodopa.
English: These results indicate that rasagiline's therapeutic concentrations are unlikely to cause any clinically significant interference with substrates of these enzymes.
Danish: Disse resultater tyder på, at terapeutiske koncentrationer af rasagilin sandsynligvis ikke giver anledning til klinisk relevant påvirkning af substrater for disse enzymer.
English: The recommended dose is 1 tablet of 1 mg taken by mouth once daily.
Danish: Den sædvanlige dosis er 1 tablet (1 mg) én gang dagligt.
English: Rasagiline was shown to be a potent, irreversible MAO-B selective inhibitor, which may cause an increase in extracellular levels of dopamine in the striatum.
Danish: Det er vist, at rasagilin er en potent, irreversibel selektiv MAO-B-hæmmer, som kan forårsage en øgning i ekstracellulær dopaminniveau i striatum.
English: • irritation of the skin (dermatitis)
Danish: • Irritation af huden (dermatitis)
English: Ask your doctor for advice prior to driving or using machines.
Danish: Spørg Deres læge til råds, inden De kører bil, motorcykel eller på cykel, og inden De arbejder med værktøj eller maskiner.
English: Conjugation of rasagiline and its metabolites was also found to be a major elimination pathway to yield glucuronides.
Danish: Konjugationen af rasagilin og dets metabolitter viste sig også at være en vigtig del af metaboliseringen til glukoronider.
English: EU/1/16/1090/001 (7 tablets - oPA/alu/PVC/alu) EU/1/16/1090/002 (10 tablets - oPA/alu/PVC/alu) EU/1/16/1090/003 (28 tablets - oPA/alu/PVC/alu) EU/1/16/1090/004 (30 tablets - oPA/alu/PVC/alu) EU/1/16/1090/005 (100 tablets - oPA/alu/PVC/alu) EU/1/16/1090/006 (112 tablets - oPA/alu/PVC/alu) EU/1/16/1090/007 (7 tablets - PVC/PVDC/alu) EU/1/16/1090/008 (10 tablets - PVC/PVDC/alu) EU/1/16/1090/009 (28 tablets - PVC/PVDC/alu) EU/1/16/1090/010 (30 tablets - PVC/PVDC/alu) EU/1/16/1090/011 (100 tablets - PVC/PVDC/alu) EU/1/16/1090/012 (112 tablets - PVC/PVDC/alu) EU/1/16/1090/013 (7 tablets - PVC/PVDC/alu) EU/1/16/1090/014 (10 tablets - PVC/PVDC/alu) EU/1/16/1090/015 (28 tablets - PVC/PVDC/alu) EU/1/16/1090/016 (30 tablets - PVC/PVDC/alu) EU/1/16/1090/017 (100 tablets - PVC/PVDC/alu) EU/1/16/1090/018 (112 tablets - PVC/PVDC/alu)
Danish: EU/1/16/1090/001 (7 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/002 (10 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/003 (28 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/004 (30 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/005 (100 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/006 (112 tabletter - oPA/alu/PVC/alu) EU/1/16/1090/007 (7 tabletter - PVC/PVDC/alu) EU/1/16/1090/008 (10 tabletter - PVC/PVDC/alu) EU/1/16/1090/009 (28 tabletter - PVC/PVDC/alu) EU/1/16/1090/010 (30 tabletter - PVC/PVDC/alu) EU/1/16/1090/011 (100 tabletter - PVC/PVDC/alu) EU/1/16/1090/012 (112 tabletter - PVC/PVDC/alu) EU/1/16/1090/013 (7 x 1 tabletter - PVC/PVDC/alu) EU/1/16/1090/014 (10 x 1 tabletter - PVC/PVDC/alu) EU/1/16/1090/015 (28 x 1 tabletter - PVC/PVDC/alu) EU/1/16/1090/016 (30 x 1 tabletter - PVC/PVDC/alu) EU/1/16/1090/017 (100 x 1 tabletter - PVC/PVDC/alu) EU/1/16/1090/018 (112 x 1 tabletter - PVC/PVDC/alu)
English: Rasagiline was not carcinogenic in rats at systemic exposure, 84-339 times the expected plasma exposures in humans at 1 mg/day.
Danish: Rasagilin var ikke carcinogen i rotter ved systemisk koncentration, som var 84-339 gange højere end det forventede plasmaniveau hos mennesker, som får 1 mg/dagligt.
English: 6.5 Nature and contents of container oPA/Al/PVC/Al.
Danish: OPA/Al/PVC/Al.
English: C-labelled rasagiline, elimination occurred primarily via urine (62.6%) and secondarily via faeces (21.8%), with a total recovery of 84.4% of the dose over a period of 38 days.
Danish: Efter peroral indgift af 14C-mærket rasagilin skete udskillelsen primært via urinen (62,6%) og sekundært via fæces (21,8%) med en samlet genfindelse på 84,4% af dosis i løbet af 38 dage.
English: - The other ingredients are microcrystalline cellulose, tartric acid, maize starch, pregelatinized maize starch, talc, stearic acid.
Danish: Øvrige indholdsstoffer: mikrokrystallinsk cellulose, vinsyre, majsstivelse, prægelatiniseret majsstivelse, talkum, stearinsyre.
English: Thus, potent CYP1A2 inhibitors may alter rasagiline plasma levels and should be administered with caution.
Danish: Potente hæmmere af CYP1A2 kan således ændre rasagilins plasmakoncentration og bør anvendes med forsigtighed.
English: There were no cases of serotonin syndrome in the rasagiline clinical program in which 115 patients were exposed concomitantly to rasagiline and tricyclics and 141 patients were exposed to rasagiline and SSRIs/ SNRIs.
Danish: Der blev ikke observeret tilfælde af serotoninsyndrom i den kliniske afprøvning af rasagilin, hvor 115 patienter fik rasagilin samtidig med tricykliske antidepressiva, og 141 patienter fik rasagilin og SSRI'ere/SNRI'ere.
English: Do not stop taking Rasagiline Mylan without first talking to your doctor.
Danish: Hvis De holder op med at tage Rasagilin Mylan Hold ikke op med at tage Rasagilin Mylan uden først at have talt med Deres læge om det.
English: • general feeling of being unwell (malaise)
Danish: • En følelse af at være sløj (utilpashed)
English: Cellulose, microcrystalline Tartaric acid
Danish: Cellulose, mikrokrystallinsk Vinsyre
English: Do not store above 25°C
Danish: Må ikke opbevares ved temperaturer over 25 °C.
English: Impulse control disorders (ICDs) can occur in patients treated with dopamine agonists and/or dopaminergic treatments.
Danish: Impulskontrolforstyrrelser kan forekomme hos patienter i behandling med dopaminagonister og/eller anden behandling med dopaminerg virkning.
English: Rasagiline Mylan is indicated for the treatment of idiopathic Parkinson's disease (PD) as monotherapy (without levodopa) or as adjunct therapy (with levodopa) in patients with end of dose fluctuations.
Danish: Rasagilin Mylan er indiceret ved behandling af idiopatisk Parkinsons sygdom som monoterapi (uden levodopa) eller som kombinationsbehandling (med levodopa) hos patienter med end-of-dose fluktuationer.
English: The efficacy of rasagiline was established in three studies: as monotherapy treatment in study I and as adjunct therapy to levodopa in the studies II and III.
Danish: Rasagilins effekt blev påvist i tre undersøgelser: som monoterapi i undersøgelse I og som kombinationsbehandling med levodopa i undersøgelse II og III.
English: Therefore, in view of the MAO inhibitory activity of rasagiline, antidepressants should be administered with caution.
Danish: Set i lyset af rasagilins MAO-hæmmende virkning bør antidepressiva derfor gives med forsigtighed.
English: Tyramine/rasagiline interaction: Results of five tyramine challenge studies (in volunteers and PD patients), together with results of home monitoring of blood pressure after meals (of 464 patients treated with 0.5 or 1 mg/day of rasagiline or placebo as adjunct therapy to levodopa for six months without tyramine restrictions), and the fact that there were no reports of tyramine/rasagiline interaction in clinical studies conducted without tyramine restriction, indicate that rasagiline can be used safely without dietary tyramine restrictions.
Danish: Tyramin/rasagilin interaktion: Resultater fra fem undersøgelser, hvor raske frivillige og patienter med Parkinsons syge fik en testdosis af tyramin, og resultaterne af hjemmeblodtryksmåling efter måltider (med 464 patienter i behandling med 0,5 eller 1 mg rasagilin dagligt eller placebo i kombinationsbehandling med levodopa i seks måneder uden restriktioner i patienternes tyraminindtagelse) samt det faktum, at der ikke sås tyramin/rasagilin-interaktion i kliniske undersøgelser gennemført uden restriktioner i tyraminindtagelse, indikerer, at det er sikkert at tage rasagilin uden at begrænse indtagelsen af tyramin i kosten.