FrancophonIA/ELRC3.0 huggingface dataset:
English: The pharmacokinetics of fulvestrant has been evaluated in a single-dose clinical study conducted in women with mild to moderate hepatic impairment (Child-Pugh class A and B).
Danish: Farmakokinetikken for fulvestrant er blevet undersøgt i et klinisk enkeltdosis-studie, der blev gennemført hos kvinder, som havde let til moderat nedsat leverfunktion, (Child-Pugh klasse A og B).
English: In the FALCON study, the number of patients who reported an adverse reaction of joint and musculoskeletal pain was 65 (31.2%) and 48 (24.1%) for fulvestrant and anastrozole arms, respectively.
Danish: I FALCON-studiet var antallet af patienter, som rapporterede en bivirkning i form af smerter i led, muskler og knogler, henholdsvis 65 (31,2%) og 48 (24,1%) for fulvestrant-armen og anastrozolarmen.
English: One dose contains 500 mg benzyl alcohol, and up to 1000 mg ethanol anhydrous.
Danish: En dosis indeholder 500 mg benzylakohol og op til 1.000 mg ethanol, vandfri.
English: No dose adjustments are recommended for patients with mild to moderate renal impairment (creatinine clearance ≥30 ml/min).
Danish: Dosisjustering anbefales ikke til patienter med let til moderat nedsat nyrefunktion (kreatinin-clearance ≥30 ml/min).
English: Women of childbearing potential Patients of child-bearing potential should be advised to use effective contraception while on treatment.
Danish: Patienter, der potentielt kan blive gravide, skal anbefales at bruge effektiv prævention under behandlingen.
English: Hepatic failurec,f, hepatitis f, elevated gamma-GT f
Danish: Ikke almindelig Leversvigtc,f, hepatitisf, forhøjet gamma-GTf
English: Store and transport refrigerated (2°C - 8°C).
Danish: Opbevares i køleskab og transporteres nedkølet (2°C - 8°C).
English: f Thrombocytopenia includes the following PTs: Thrombocytopenia, Platelet count decreased.
Danish: f Thrombocytopeni inkluderer de følgende PTs: thrombocytopeni, nedsat trombocyttal.
English: Table 6 Efficacy results in visceral and non-visceral disease from PALOMA3 study (intentto-treat population)
Danish: Tabel 6 Effektresultater i visceral og ikke-visceral sygdom fra PALOMA-3-studiet (intent-to-treat-population)
English: • Allergic (hypersensitivity) reactions, including swelling of the face, lips, tongue and/or throat that may be signs of anaphylactic reactions
Danish: • Allergiske reaktioner (overfølsomhed), der kan omfatte hævelser i ansigt, læber, tunge og/eller svælg, som kan være tegn på en anafylaktisk reaktion
English: Venous thromboembolisma
Danish: Venøs thromboembolismea, hedeture
English: A total of 335 patients in the fulvestrant plus palbociclib arm and 166 patients in the fulvestrant plus placebo arm completed the questionnaire at baseline and at least 1 post-baseline visit.
Danish: 166 patienter i fulvestrant plus placebo-armen udfyldte spørgeskemaet ved baseline og ved mindst et besøg efterfølgende.
English: Fulvestrant Mylan has 2 pack presentations, either a pack containing 1 glass pre-filled syringe or a pack containing 2 glass pre-filled syringes.
Danish: Fulvestrant Myaln leveres i 2 forskellige pakninger, enten en pakning indeholdende 1 fyldt glasinjektionssprøjte eller en pakning med 2 fyldte glas-injektionssprøjter.
English: • Injection site reactions, such as pain and/or inflammation
Danish: • Reaktion ved injektionsstedet som smerte og eller betændelseslignende tilstand (inflammation)
English: Fulvestrant Mylan contains 10% w/v ethanol (alcohol) i.e. up to 1000 mg per dose, equivalent to 20 ml beer or 8 ml wine per dose.
Danish: Fulvestrant Mylan indeholder 10 vol % ethanol (alkohol), dvs. op til 1.000 mg pr. dosis, svarende til 20 ml øl eller 8 ml vin pr. dosis.
English: • Thick, whitish vaginal discharge and candidiasis (infection)
Danish: • Tykt, hvidligt udflåd fra skeden og svamp (candidainfektion)
English: Very common Hypersensitivity reactionse Uncommon
Danish: Meget almindelig Overfølsomhedsreaktionere Ikke almindelig Anafylaktiske reaktioner
English: The geometric mean (standard deviation) steady state trough concentration (Cmin,ss) and AUCss was 4.2 (0.9) ng/mL and 3680 (1020) ng*hr/mL, respectively.
Danish: Den geometriske, gennemsnitlige steady-state-(ss)dalkoncentration af fulvestrant (Cmin,ss) og AUCss var henholdsvis 4,2 (0,9) ng/ml og 3.680 (1.020) ng*t/ml (standardafvigelse).
English: This study compared the efficacy and safety of fulvestrant 500 mg (n=362) with fulvestrant 250 mg (n=374).
Danish: I dette studie blev virkning og sikkerhed af fulvestrant 500 mg (n=362) sammenlignet med fulvestrant 250 mg (n=374).
English: The paediatric patients were aged 1 to 8 years and received 4 mg/kg monthly intramuscular dose of fulvestrant.
Danish: De pædiatriske patienter var i alderen 1 til 8 år og fik en intramuskulær dosis på 4 mg fulvestrant/kg hver måned.
English: When fulvestrant is given in combination with palbociclib, it is important that you also read the package leaflet for palbociclib.
Danish: Når fulvestrant gives i kombination med palbociclib er det vigtigt, at du også læser indlægssedlen for palbociclib.
English: Fulvestrant Mylan contains benzyl alcohol
Danish: Fulvestrant Mylan indeholder benzylalkohol
English: A 2-week study in healthy postmenopausal volunteers treated with 20 μg per day ethinylestradiol showed that pre-treatment with fulvestrant 250 mg resulted in significantly reduced stimulation of the postmenopausal endometrium, compared to pre-treatment with placebo, as judged by ultrasound measurement of endometrium thickness.
Danish: Et studie på 2 uger med raske postmenopausale frivillige forsøgspersoner, behandlet med 20 μg ethinylestradiol dagligt, viste, at præmedicinering med fulvestrant 250 mg resulterede i en signifikant reduceret stimulation af det postmenopausale endometrium, sammenlignet med placebo, vurderet via ultralydsmålinger af endometriets tykkelse.
English: • Numbness, tingling and pain
Danish: • Følelsesløshed, snurrende fornemmelse og smerter
English: Infections and infestations Very common Infectionsb Blood and lymphatic system disorders Very common Neutropeniac Leukopeniad Anaemiae Thrombocytopeniaf Uncommon Febrile neutropenia Metabolism and nutrition disorders Very common Decreased appetite Nervous system disorders Common Dysgeusia Eye disorders Common Lacrimation increased Vision blurred Dry eye Respiratory, thoracic and mediastinal disorders Common Epistaxis Gastrointestinal disorders Very common Nausea
Danish: Infektioner og parasitære sygdomme Meget almindelig Infektionerb Blod og lymfesystem Meget almindelig Neutropenic Leukopenid Anæmie Thrombocytopenif Ikke almindelig Febril neutropeni Metabolisme og ernæring Meget almindelig Nedsat appetit Nervesystemet Almindelig Dysgeusi Øjne Almindelig Øget tåresekretion Sløret syn Tørre øjne Luftveje, thorax og mediastinum Almindelig Epistaxis Mave-tarm-kanalen Meget almindelig Kvalme
English: Breast-feeding must be discontinued during treatment with fulvestrant.
Danish: Amning skal ophøre under behandling med fulvestrant.
English: Comparison between groups (Fulvestrant 500 mg/ Fulvestrant 250 mg) Hazard ratio
Danish: Sammenligning mellem grupper (Fulvestrant 500 mg/ Fulvestrant 250 mg) Hazard ratio
English: DOR (measurable disease) [months (95% CI)]
Danish: DOR (målbar sygdom) [måneder (95 % CI)]
English: However, if you feel tired after treatment do not drive or use machines.
Danish: Hvis du føler dig træt efter behandling med Fulvestrant Mylan, bør du ikke køre bil eller betjene maskiner.
English: d Leukopenia includes the following PTs: Leukopenia, White blood cell count decreased.
Danish: d Leukopeni inkluderer de følgende PTs: leukopeni, nedsat antal hvide blodlegemer.
English: Mucosal inflammation, Oral pain, Oropharyngeal discomfort, Oropharyngeal pain, Stomatitis.
Danish: slimhindeinflammation, mundsmerter, orofaryngealt ubehag, orofaryngeale smerter, stomatitis.
English: • Remove glass syringe barrel from tray and check that it is not damaged.
Danish: • Tag glassprøjten ud af bakken og undersøg, om den er
English: massive uncontrolled effusions [pleural, pericardial, peritoneal], pulmonary lymphangitis, and over 50% liver involvement), were not eligible for enrolment into the study.
Danish: for livstruende komplikationer på kort sigt (herunder patienter med massivt ukontrolleret ekssudat [pleural, perikardiel, peritoneal], pulmonal lymfangitis samt mere end 50 % leverpåvirkning), var ikke egnede til deltagelse i studiet.
English: An open-label phase 2 study investigated the safety, efficacy and pharmacokinetics of fulvestrant in 30 girls aged 1 to 8 years with Progressive Precocious Puberty associated with McCune Albright Syndrome (MAS).
Danish: Et åben-label fase-2-studie undersøgte sikkerhed og virkning samt farmakokinetiske egenskaber ved fulvestrant hos 30 piger i alderen 1 til 8 år med progressiv pubertas præcox i forbindelse med McCune Albright-syndrom (MAS).
English: • Increase of bilirubin (bile pigment produced by the liver)
Danish: • Forhøjet mængde bilirubin (galdefarvestof, der dannes i leveren)
English: In rats, a reversible reduction in female fertility and embryonic survival, dystocia and an increased incidence of foetal abnormalities including tarsal flexure were observed.
Danish: Hos rotter sås reversibel nedsat kvindelig fertilitet og embryo-overlevelse, dyctocia samt en øget forekomst af fosterabnormaliteter inkl.
English: Fulvestrant Mylan 500 mg (2 x 250 mg/5 ml solution for injection) should be administered using two pre-filled syringes, see section 3.
Danish: Fulvestrant Mylan 500 mg (2 x 250 mg/5 ml injektionsvæske, opløsning) skal administreres med 2 fyldte injektionssprøjter, se afsnit 3.
English: Fulvestrant Mylan is used either:
Danish: Fulvestrant Mylan anvendes enten
English: Neuropathy peripherale, sciaticae
Danish: Perifer neuropatie, iskiase
English: The hazard ratio of fulvestrant 250 mg to anastrozole for time to death was 1.01 (95% CI 0.86 to 1.19).
Danish: Hazard ratio for fulvestrant 250 mg i forhold til anastrozol for tid til død, var 1,01 (95% konfidensinterval, 0,86 til 1,19).
English: To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease, or epilepsy.
Danish: Anvend kun dette lægemiddel til børn, gravide eller ammende kvinder og patienter i højrisikogruppe såsom patienter med epilepsi og leversygdomme efter aftale med lægen.
English: Exposure to temperatures below 2°C will not damage the product providing it is not stored below -20°C.
Danish: Temperaturer under 2°C vil ikke beskadige produktet, forudsat at det ikke opbevares ved temperaturer under -20°C.
English: Fulvestrant should be used with caution in patients with severe renal impairment (creatinine clearance less than 30 ml/min).
Danish: Fulvestrant skal anvendes med forsigtighed til patienter med meget nedsat nyrefunktion (kreatininclearance < 30 ml/min).
English: What Fulvestrant Mylan contains - The active substance is fulvestrant.
Danish: Fulvestrant Mylan indeholder: - Aktivt stof: fulvestrant.
English: 6.6 Special precautions for disposal and other handling
Danish: 6.6 Regler for bortskaffelse og anden håndtering Administrationsinstruktion
English: - The other ingredients (excipients) are benzyl benzoate, benzyl alcohol, ethanol, anhydrous, castor oil, refined.
Danish: - Øvrige indholdsstoffer (hjælpestoffer): benzylbenzoat, benzylalkohol, vandfri ethanol, renset ricinusolie.
English: A total of 521 pre/peri- and postmenopausal women who had progressed on or within 12 months from completion of adjuvant endocrine therapy on or within 1 month from prior endocrine therapy for advanced disease, were randomised 2:1 to fulvestrant plus palbociclib or fulvestrant plus placebo and stratified by documented sensitivity to prior hormonal therapy, menopausal status at study entry (pre/peri- versus postmenopausal), and presence of visceral metastases.
Danish: I alt 521 præ-/peri- og postmenopausale kvinder, som havde progredieret under eller inden for 12 måneder efter fuldførelse af adjuverende endokrin behandling, under eller inden for 1 måned efter tidligere endokrin behandling mod fremskreden sygdom, blev randomiseret 2:1 til fulvestrant plus palbociclib eller fulvestrant plus placebo og stratificeret efter dokumenteret følsomhed over for tidligere hormonbehandling, menopausalstatus ved studiets start (præ-/peri- versus postmenopausal) og forekomst af viscerale metastaser.
English: Caution should be taken if injecting Fulvestrant Mylan at the dorsogluteal site due to the proximity of the underlying sciatic nerve.
Danish: Der bør udvises forsigtighed, hvis Fulvestrant Mylan injiceres i det dorsogluteale område på grund af den nært underliggende iskiasnerve.
English: A two-year oncogenicity study in rats (intramuscular administration of fulvestrant) showed increased incidence of ovarian benign granulosa cell tumours in female rats at the high dose, 10 mg/rat/15 days and an increased incidence of testicular Leydig cell tumours in males.
Danish: Et to-årigt onkogenicitetsstudie med rotter (intramuskulær administration af fulvestrant) viste øget forekomst af godartede ovarietumorer i granulosa-celler hos hunrotter ved den høje dosis på 10 mg/rotte/15 dage og en øget forekomst af Leydigs tumorer i testiklerne hos hanrotter.
English: For user convenience, the needle bevel- up position is oriented to the lever arm (see Figure 4).
Danish: For brugervenlighed vendes kanylens skråspids opad mod vippearmen (se figur 4).
English: Benzyl benzoate Benzyl alcohol Ethanol, anhydrous Castor oil, refined
Danish: Benzylbenzoat Benzylalkohol Ethanol, vandfri Ricinusolie, renset
English: -AI subgroup (n=313)a
Danish: -AI-undergruppe (n=313)a
English: Benzyl benzoate
Danish: Benzylbenzoat
English: The study included 423 patients whose disease had recurred or progressed during anti-estrogen therapy (AE subgroup) and 313 patients whose disease had recurred or progressed during aromatase inhibitor therapy (AI subgroup).
Danish: Studiet omfattede 423 patienter med recidiverende eller progredierende sygdom under antiøstrogen-behandlingen (AE-undergruppe), og 313 patienter med recidiverende eller progredierende sygdom under aromatasehæmmer-behandlingen (AI-undergruppe).
English: At the no-effect level for these findings, systemic exposure levels (AUC) were, in rats, approximately 1.5-fold the expected human exposure levels in females and 0.8-fold in males, and in mice, approximately 0.8fold the expected human exposure levels in both males and females.
Danish: Ved niveauet ”ingen effekt” for disse fund var den systemiske eksponering (AUC) cirka 1,5 gange niveauet af den forventede humane eksponeringer hos hunrotter og 0,8 gange hos hanrotter.
English: Comparison between groups (Fulvestrant 500 mg/Fulvestrant 250 mg)
Danish: Sammenligning melle grupper (Fulvestrant 500 mg/Fulvestrant 250 mg)
English: You must not breast-feed while on treatment with Fulvestrant Mylan.
Danish: Du må ikke amme, mens du behandles med Fulvestrant Mylan.
English: Interference with estradiol antibody assays
Danish: Interferens med estradiol-antistofanalyser
English: Very common Astheniaa, injection site reactionsb Common
Danish: Meget almindelig Astenia, reaktioner ved injektionsstedetb
English: Fulvestrant is indicated in patients whose disease had recurred or progressed on an anti-estrogen therapy.
Danish: Fulvestrant er indiceret til patienter med recidiverende eller progredierende sygdom under antiøstrogenbehandling.
English: 4.4 Special warnings and precautions for use Fulvestrant should be used with caution in patients with mild to moderate hepatic impairment (see sections 4.2, 4.3 and 5.2).
Danish: 4.4 Særlige advarsler og forsigtighedsregler vedrørende brugen Fulvestrant skal anvendes med forsigtighed til patienter med let til moderat nedsat leverfunktion (se pkt.
English: • as monotherapy for the treatment of estrogen receptor positive, locally advanced or metastatic breast cancer in postmenopausal women: not previously treated with endocrine therapy, or with disease relapse on or after adjuvant antiestrogen therapy, or disease progression on antiestrogen therapy.
Danish: • som monoterapi til behandling af østrogen-receptor-positiv, lokal fremskreden eller metastatisk brystkræft hos postmenopausale kvinder: - der ikke tidligere har modtaget endokrin behandling, eller - med sygdomstilbagefald under eller efter adjuverende behandling med antiøstrogen, eller sygdomsprogression under antiøstrogenbehandling.
English: Keep the pre-filled syringe in the original package in order to protect from light.
Danish: Opbevar den fyldte sprøjte i den originale pakning for at beskytte mod lys.
English: Temperature excursions have a cumulative effect on the product quality and the 28 day time period must not be exceeded over the duration of the shelf life of Fulvestrant Mylan (see section 6.3).
Danish: Temperaturudsving har en kumulativ virkning på produktkvaliteten, og perioden på 28 dage må ikke overskrides i løbet af Fulvestrant Mylans opbevaringstid (se pkt.
English: Fifty-five percent (55.0%) of patients had visceral metastasis at baseline.
Danish: 55% af patienterne havde viscerale metastaser ved studiets udgangspunkt.
English: Neoadjuvant treatment for up to 16 weeks in breast cancer patients treated with either fulvestrant 500 mg or fulvestrant 250 mg did not result in clinically significant changes in endometrial thickness, indicating a lack of agonist effect.
Danish: Neoadjuverende behandling af brystkræftpatienter i op til 16 uger, med enten fulvestrant 500 mg eller fulvestrant 250 mg, viste ingen klinisk signifikante ændringer i endometriets tykkelse, hvilket indikerer manglende agonistvirkning.
English: What you need to know before you use Fulvestrant Mylan
Danish: Det skal du vide, før du begynder at bruge Fulvestrant Mylan
English: With the other hand, take hold of the cap (A) and carefully tilt back and forth until the cap disconnects and can be pulled off, do not twist (see Figure 1).
Danish: Hold fast i låget (A) med den anden hånd og vip forsigtigt frem og tilbage, indtil låget brækkes af og kan trækkes af.
English: In the pooled dataset of fulvestrant monotherapy, the most frequently reported adverse reactions were injection site reactions, asthenia, nausea, and increased hepatic enzymes (ALT, AST, ALP).
Danish: I de poolede datasæt med fulvestrant som monoterapi var de hyppigst rapporterede bivirkninger reaktioner ved injektionsstedet, asteni, kvalme og forhøjede leverenzymer (ALAT, ASAT, ALP).
English: Stomatitisg Diarrhoea Vomiting Skin and subcutaneous tissue disorders Very common Alopecia Rashh Common Dry skin General disorders and administration site conditions Very common Fatigue Pyrexia Common Asthenia Investigations Common AST increased ALT increased
Danish: Stomatitisg Diarré Opkastning Hud og subkutane væv Meget almindelig Alopeci Udslæth Almindelig Tør hud Almene symptomer og reaktioner på administrationsstedet Meget almindelig Træthed Feber Almindelig Asteni Undersøgelser Almindelig Forhøjet ASAT Forhøjet ALAT
English: After temperature excursions, the product should be returned immediately to the recommended storage conditions (store and transport in a refrigerator 2°C - 8°C).
Danish: Efter temperaturudsving skal produktet straks igen opbevares ved de anbefalede opbevaringsforhold (opbevares i køleskab og transporteres nedkølet ved 2°C - 8°C).
English: A Phase 3, randomised, double-blind, double-dummy, multicentre study of fulvestrant 500 mg versus anastrozole 1 mg was conducted in postmenopausal women with ER-positive and/or PgR-positive locally advanced or metastatic breast cancer who had not previously been treated with any hormonal therapy.
Danish: Der blev udført et randomiseret, dobbeltblindet, dobbelt-dummy, fase 3-multicenterstudie med fulvestrant 500 mg versus anastrozol 1 mg med postmenopausale kvinder med ER-positiv og/eller PgR-positiv lokalt fremskreden eller metastatisk brystkræft, som ikke tidligere havde fået hormonbehandling.
English: Patients with advanced/metastatic, symptomatic, visceral spread, that were at risk of life-threatening complications in the short term (including patients with
Danish: Patienter med fremskreden/metastatisk, symptomatisk, visceral spredning, som havde risiko
English: A Phase 3, international, randomised, double-blind, parallel-group, multicentre study of fulvestrant 500 mg plus palbociclib 125 mg versus fulvestrant 500 mg plus placebo was conducted in women with HR-positive, HER2-negative locally advanced breast cancer not amenable to resection or radiation therapy with curative intent or metastatic breast cancer, regardless of their menopausal status, whose disease progressed after prior endocrine therapy in the (neo) adjuvant or metastatic setting.
Danish: Der blev udført et internationalt, randomiseret, dobbeltblindet, fase 3-multicenterstudie med parallelgrupper med fulvestrant 500 mg plus palbociclib 125 mg versus fulvestrant 500 mg plus placebo med kvinder med HR-positiv, HER2-negativ lokalt fremskreden brystkræft, der ikke var modtagelig for resektion eller strålebehandling med henblik på helbredelse, eller metastatisk brystkræft, uanset menopausalstatus, hvis sygdom progredierede efter tidligere endokrin behandling i (neo)adjuverende eller metastatisk regi.
English: Figure 1 Kaplan-Meier Plot of Progression-Free Survival (Investigator Assessment, Intent-To-Treat Population) ─ FALCON Study
Danish: Figur 1 Kaplan-Meier-diagram over progressionsfri overlevelse (investigatorvurdering, intentto-treat-population) ─ FALCON-studiet
English: • Anaphylactic reactions
Danish: • Anafylaktisk reaktion
English: Reproductive system and breast disorders Common
Danish: Det reproduktive system og mammae
English: Neoadjuvant treatment for up to 16 weeks in breast cancer patients with either fulvestrant 500 mg or fulvestrant 250 mg did not result in clinically significant changes in serum bone-turnover markers.
Danish: Neoadjuverende behandling med enten fulvestrant 500 mg eller fulvestrant 250 mg til brystkræftpatienter i op til 16 uger resulterede ikke i klinisk signifikante ændringer af knogle-turnover-markører i serum.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION One pre-filled syringe contains 250 mg fulvestrant in 5 ml solution.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING En fyldt injektionssprøjte indeholder 250 mg fulvestrant i 5 ml opløsning.
English: How to use Fulvestrant Mylan
Danish: Sådan skal du bruge Fulvestrant Mylan
English: Two phase-3 clinical studies were completed in a total of 851 postmenopausal women with advanced breast cancer who had disease recurrence on or after adjuvant endocrine therapy or progression following endocrine therapy for advanced disease.
Danish: To kliniske fase 3-studier blev gennemført med i alt 851 postmenopausale kvinder med fremskreden brystkræft, som havde sygdomstilbagefald under, eller efter, adjuvant endokrin behandling, eller progression efter endokrin behandling for fremskreden sygdom.
English: Each pre-filled syringe (5 ml) contains 250 mg fulvestrant.
Danish: En fyldt injektionssprøjte (5 ml) indeholder 250 mg fulvestrant.
English: ORR Odds Ratio (95% CI) and p-value
Danish: ORR-odds ratio (95% CI) og pværdi
English: Two clear type 1 glass pre-filled syringes with polypropylene plunger rod, fitted with a tamper-evident closure, each containing 5 ml Fulvestrant Mylan solution for injection.
Danish: To klare type 1 fyldte glas-injektionssprøjter med et polystyren pumpestempel, der er lukket med sikkerhedsforsegling, hver indeholdende 5 ml Fulvestrant Mylan injektionsvæske, opløsning.
English: For the subgroup of patients with disease limited to non-visceral metastasis (n=208), the HR was 0.592 (95% CI: 0.419, 0.837) for the fulvestrant arm compared to the anastrozole arm. For the subgroup of patients with visceral metastasis (n=254), the HR was 0.993 (95% CI: 0.740, 1.331) for the fulvestrant arm compared to the anastrozole arm.
Danish: For undergruppen af patienter med sygdom, der var begrænset til ikkeviscerale metastaser (n=208), var hazard ratio 0,592 (95% CI: 0,419; 0,837) for fulvestrant-armen sammenlignet med anastrozol-armen.
English: Figure 2 Kaplan-Meier plot of progression-free survival (investigator assessment, intentto-treat population) - PALOMA3 study
Danish: Kaplan-Meier-diagram over progressionsfri overlevelse (investigatorvurdering, intent-to-treat-population) - PALOMA-3-studiet