FrancophonIA/ELRC3.0 huggingface dataset:
English: It is not recommended to use ritonavir in patients receiving rivaroxaban, due to the risk of increased bleeding (see section 4.5).
Slovenian: Zaradi večjega tveganja za krvavitve ritonavirja ni priporočljivo uporabljati pri bolnikih, ki prejemajo rivaroksaban (glejte poglavje 4.5).
English: 400 q12 h
Slovenian: 400 na 12 ur
English: 50, oral single dose
Slovenian: 50, posamičen odmerek
English: Ritonavir co-administration is likely to result in increased plasma concentrations of astemizole and terfenadine and is therefore contraindicated (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja ponavadi zviša koncentracijo astemizola in terfenadina v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: Dosage conversion from oral solution to tablets for children
Slovenian: Pretvorba odmerkov s peroralne raztopine na filmsko obložene tablete za otroke: odmerek peroralne raztopine odmerek filmsko obloženih tablet
English: The co-administration of vorapaxar with ritonavir is not recommended (see section 4.4 and refer to the vorapaxar SmPC).
Slovenian: Sočasna uporaba vorapaksarja z ritonavirjem ni priporočljiva (glejte poglavje 4.4 in povzetek glavnih značilnosti zdravila za vorapaksar).
English: 100q12h ↓ 39% ↓ 24% Concomitant use of ritonavir dosed as an antiretroviral agent and voriconazole is contraindicated due to reduction in voriconazole concentrations (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja, odmerjanega kot protiretrovirusno zdravilo, in vorikonazola je kontraindicirana zaradi zmanjšane kocentracije vorikonazola (glejte poglavje 4.3).
English: Ritonavir may modify P-glycoprotein mediated fexofenadine efflux when dosed as an antiretroviral agent or as a pharmacokinetic enhancer resulting in increased concentrations of fexofenadine.
Slovenian: Ritonavir, odmerjan kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, lahko spremeni s P-glikoproteinom posredovani iztok feksofenadina in tako zviša koncentracijo feksofenadina.
English: Ritonavir increases the serum levels of amprenavir as a result of CYP3A4 inhibition.
Slovenian: Ritonavir zviša plazemske koncentracije simeprevirja, kar je posledica zaviranja CYP3A4.
English: 40 mg, single dose
Slovenian: 20 mg, enkratni odmerek 40 mg, enkratni odmerek 40 mg, enkratni odmerek
English: Human studies with radiolabelled ritonavir demonstrated that the elimination of ritonavir was primarily via the hepatobiliary system; approximately 86% of radiolabel was recovered from stool, part of which is expected to be unabsorbed ritonavir.
Slovenian: Približno 86 % izotopa so našli v blatu, del tega gre verjetno na račun neabsorbiranega ritonavirja.
English: Careful monitoring of therapeutic and adverse effects is recommended when these medicines are concomitantly administered with antiretroviral doses of ritonavir.
Slovenian: Med sočasno uporabo teh zdravil in protiretrovirusnih odmerkov ritonavirja je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov .
English: For further information, physicians should refer to the Summary of Product Characteristics for amprenavir.
Slovenian: Za dodatne informacije glejte povzetek glavnih značilnosti zdravila za amprenavir.
English: It is advisable to monitor renal function in patients with renal function impairment.
Slovenian: Pri bolnikih z okvarjenim delovanjem ledvic je priporočljivo nadzirati delovanje ledvic.
English: Abdominal pain (upper and lower), nausea, diarrhoea (including severe with electrolyte imbalance), vomiting, dyspepsia
Slovenian: Bolezni prebavil zelo pogosti bolečine v trebuhu (v zgornjem in spodnjem predelu), navzea, driska (vključno s hudo drisko in elektrolitskimi motnjami), bruhanje, dispepsija pogosti anoreksija, flatulenca, razjede v ustih, gastrointestinalna krvavitev, gastroezofagealna refluksna bolezen, pankreatitis
English: 500q12h ↑ 3.4-fold ↑ 55% Ritonavir inhibits CYP3A-mediated metabolism of ketoconazole.
Slovenian: ↑ 29-krat Ritonavir ↓ 40% ND Ritonavir zavira CYP3A in tako zviša koncentracijo tipranavirja v serumu.
English: Caution should be exercised in administering ceritinib with ritonavir.
Slovenian: Pri uporabi ceritiniba z ritonavirjem je potrebna previdnost.
English: 1,000 q12 h
Slovenian: 1000 na 12 ur
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A4 and as a result is expected to increase the plasma concentrations of erythromycin and itraconazole.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A4, zato je treba pričakovati, da zviša koncentracijo eritromicina in itrakonazola v plazmi.
English: Anticoagulants Rivaroxaban
Slovenian: Antikoagulanti
English: Uncommon: may affect up to 1 in 100 people
Slovenian: Občasni: pojavijo se lahko pri 1 od 100 bolnikov - sladkorna bolezen
English: Antiasthmatic Theophylline1
Slovenian: Teofilin1
English: When ritonavir is used as a pharmacokinetic enhancer of other PIs, consult the Summary of Product Characteristics of the co-administered protease inhibitor for contraindications.
Slovenian: Če je ritonavir uporabljen kot farmakokinetični stopnjevalec drugih zaviralcev proteaz, je treba glede kontraindikacij upoštevati povzetek glavnih značilnosti sočasno uporabljenega zaviralca proteaz.
English: Ritonavir dosed as a pharmacokinetic enhancer The interaction profiles of HIV-protease inhibitors, co-administered with low dose ritonavir, are dependent on the specific co-administered protease inhibitor.
Slovenian: Značilnosti medsebojnega delovanja zaviralcev proteaz HIV, uporabljenih sočasno z majhnimi odmerki ritonavirja, so odvisne od specifičnega sočasno uporabljenega zaviralca proteaz.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 100 mg of ritonavir.
Slovenian: NAVEDBA ENE ALI VEČ UČINKOVIN Ena filmsko obložena tableta vsebuje 100 mg ritonavirja.
English: Serum concentrations may be increased due to CYP3A4 inhibition by ritonavir.
Slovenian: Serumske koncentracije se lahko povečajo zaradi CYP3A zavrtja z ritonavirjem.
English: Anti-gout treatments Colchicine
Slovenian: Zdravilo za zdravljenje infekcij z mikobakterijami
English: In the absence of pharmacokinetic studies in patients with stable severe hepatic impairment (Child Pugh Grade C) without decompensation, caution should be exercised when ritonavir is used as a pharmacokinetic enhancer as increased levels of the co-administered PI may occur.
Slovenian: Farmakokinetičnih študij pri bolnikih s stabilno hudo okvaro jeter (razred C po Child-Pughu) brez dekompenzacije ni.
English: Talk to your doctor before taking Ritonavir Mylan.
Slovenian: Pred začetkom jemanja zdravila Ritonavir Mylan se posvetujte z zdravnikom.
English: Refer to the Summary of Product Characteristics for atazanavir for further details.
Slovenian: Za dodatne informacije glejte povzetek glavnih značilnosti zdravila za atazanavir.
English: How to store Ritonavir Mylan
Slovenian: Shranjevanje zdravila Ritonavir Mylan
English: ↑ 2.5-fold
Slovenian: ↑ 2,5-krat
English: Clinical trials confirmed the safety and efficacy of fosamprenavir 700 mg twice daily with ritonavir 100 mg twice daily.
Slovenian: Klinična preskušanja so potrdila varnost in učinkovitost 700 mg fosamprenavirja dvakrat na dan s 100 mg ritonavirja dvakrat na dan. Ritonavir s fosamprenavirjem ni raziskan v odmerkih, večjih od 100 mg dvakrat na dan. Za dodatne informacije glejte povzetek glavnih značilnosti zdravila za fosamprenavir.
English: Due to the risk of bedaquiline related adverse events, co-administration should be avoided.
Slovenian: Sočasni uporabi se je treba zaradi tveganja za neželene učinke bedakilina izogibati.
English: Concentrations of colchicine are expected to increase when co-administered with ritonavir.
Slovenian: Pri sočasni uporabi kolhicina z ritonavirjem je mogoče pričakovati zvišano koncentracijo kolhicina.
English: Generics UK Limited Station Close Potters Bar Hertfordshire EN6 1TL
Slovenian: Generics UK Limited Station Close
English: You must not take Ritonavir Mylan with sildenafil if you suffer from pulmonary arterial hypertension (see also section 2.
Slovenian: Zdravila Ritonavir Mylan ne smete jemati s sildenafilom, če imate pljučno arterijsko hipertenzijo (glejte tudi poglavje 2, Kaj morate vedeti, preden boste vi ali vaš otrok vzeli zdravilo Ritonavir Mylan).
English: Ritonavir co-administration is likely to result in increased plasma concentrations of alfuzosin and is therefore contraindicated (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja ponavadi zviša koncentracijo alfuzosina v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: Due to CYP3A inhibition by ritonavir, concentrations of lomitapide are expected to increase.
Slovenian: Zaradi zavrtja CYP3A z ritonavirjem se pričakuje povečanje koncentracij lomitapida.
English: 100q12h ↓ 22% ↓ 21%
Slovenian: 100 na 12 ur ↓ 39%
English: As ritonavir is primarily metabolised by the liver, ritonavir may be appropriate for use with caution as a pharmacokinetic enhancer in patients with renal insufficiency depending on the specific protease inhibitor with which it is co-administered.
Slovenian: Zato utegne biti potrebna previdnost, če je uporabljen kot farmakokinetični stopnjevalec pri bolnikih z insuficienco ledvic; to je odvisno od specifičnega zaviralca proteaz, s katerim je uporabljen sočasno.
English: Rifampicin and saquinavir (used for tuberculosis and HIV, respectively) as serious liver damage can occur when taken with ritonavir.
Slovenian: Rifampicin in sakvinavir (prvi je zdravilo proti tuberkulozi, drugi zdravilo proti HIV), ker lahko sočasna uporaba z ritonavirjem povzroči resno okvaro jeter Bosentan, riociguat (za pljučno arterijsko hipertenzijo), ker lahko ritonavir poveča koncentracijo tega zdravila v krvi.
English: Desipramine
Slovenian: Antidepresivi
English: Careful monitoring of serum levels or therapeutic effects is recommended when atovaquone is concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo atovakona in ritonavirja je priporočljivo natančno nadziranje koncentracije v serumu in terapevtskih učinkov.
English: Ritonavir co-administration is likely to result in increased plasma concentrations of clozapine or pimozide and is therefore contraindicated (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja ponavadi zviša koncentracijo klozapina in pimozida v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A4 and as a result is expected to increase the plasma concentrations of carbamazepine.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A4, zato je treba pričakovati, da zviša koncentracijo karbamazepina v plazmi.
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A4 and as a result is expected to increase the plasma concentrations of fentanyl.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A4, zato je treba pričakovati, da zviša koncentracijo fentanila v plazmi.
English: Medicinal Product Class
Slovenian: FARMACEVTSKI PODATKI
English: The reduction of the rifabutin dose to 150 mg 3 times per week may be indicated for select PIs when co-administered with ritonavir as a pharmacokinetic enhancer.
Slovenian: Pri nekaterih zaviralcih proteaz, sočasno uporabljenih z ritonavirjem kot farmakokinetičnim stopnjevalcem, je indicirano zmanjšanje odmerka rifabutina na 150 mg trikrat na teden.
English: ↑ 14 fold
Slovenian: ↑ 13-krat
English: 100 q12 h
Slovenian: 100na 12 ur
English: • allergic reactions including skin rashes
Slovenian: - alergijske reakcije, vključno z izpuščaji na koži (lahko so rdeči, privzdignjeni, srbeči),
English: Dosage reduction of desipramine is recommended when co-administered with ritonavir dosed as an antiretroviral agent.
Slovenian: Sildenafil za zdravljenje erektilne disfunkcije je treba previdno uporabljati z ritonavirjem, odmerjanim kot protiretrovirusnim zdravilom ali
English: 600 q12 h Delavirdine1
Slovenian: 600 na 12 ur ↑ 13-krat
English: 20 mg, single dose
Slovenian: 20, posamičen odmerek
English: Antianginal
Slovenian: Antimikotik
English: 700 q12 h
Slovenian: Fosamprenavir 700 na 12 ur
English: Atovaquone
Slovenian: Bupropion
English: Tablet dose
Slovenian: posamičen odmerek
English: Ritonavir co-administration is likely to result in increased plasma concentrations of cisapride and is therefore contraindicated (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja ponavadi zviša koncentracijo cisaprida v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: (See section 4 Possible side effects) Dizziness, lightheadedness, fainting spells or abnormal heartbeat.
Slovenian: Omotica, omotičnost, napadi omedlevice ali nenormalno bitje srca.
English: Careful monitoring of serum levels or therapeutic effects is recommended when these medicines are concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo teh zdravil in ritonavirja je priporočljivo natančno nadziranje koncentracije v serumu in terapevtskih učinkov.
English: Careful monitoring of therapeutic and adverse effects is recommended when carbamazepine is concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo karbamazepina in ritonavirja je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov.
English: Careful monitoring of therapeutic and adverse effects is recommended when buspirone concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo buspirona in ritonavirja je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov.
English: 25-O-desacetyl rifabutin metabolite
Slovenian: Rifabutin1 Presnovek 25-O-dezacetilrifabutin
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A and as a result is expected to increase the plasma concentrations of loratadine.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A, zato je treba pričakovati, da zviša koncentracijo loratadina v plazmi.
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A and as a result is expected to increase the plasma concentrations of buspirone.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A, zato je treba pričakovati, da zviša koncentracijo buspirona v plazmi.
English: 600q12h ↓ 66% ↓ 62% Bupropion is primarily metabolised by CYP2B6.
Slovenian: Bupropion se primarno presnavlja s CYP2B6.
English: Anticonvulsants Carbamazepine
Slovenian: Karbamazepin
English: Alprazolam metabolism was inhibited following the introduction of ritonavir.
Slovenian: Po uvedbi ritonavirja se je pojavilo zavrtje presnove alprazolama.
English: 200q12h ↑ 28% ↑ 9% Careful monitoring of therapeutic and adverse effects is recommended when prednisolone is concomitantly administered with ritonavir.
Slovenian: 600 na 12 ur 2 uri pozneje Didanozin ↓ 13 % ↔ Ritonavir je priporočljivo jemati s hrano, didanozin pa je treba vzeti na prazen želodec.
English: Hypersensitivity including urticaria, and face oedema
Slovenian: Bolezni imunskega sistema pogosti probčutljivost vključno z urtikarijo in edemom obraza redki anafilaksija
English: Effect on Coadministered Medicinal Products
Slovenian: Vpliv na Cmax sočasno uporabljenega zdravila
English: Dysgeusia, oral and peripheral paraesthesia, headache, dizziness, peripheral neuropathy
Slovenian: Bolezni živčevja zelo pogosti dizgevzija, parestezija okrog ust in periferna parestezija, glavobol, omotica, periferna nevropatija pogosti nespečnost, anksioznost, zmedenost, motnje pozornosti, sinkopa, konvulzije
English: Clarithromycin doses greater than 1 g per day should not be co-administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Slovenian: Hkrati z ritonavirjem, odmerjanimkot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, ne smete uporabljati odmerkov klaritromicina, večjih od 1 g na dan.
English: The HMG-CoA reductase inhibitors simvastatin and lovastatin are highly dependent on CYP3A for metabolism, thus concomitant use of ritonavir with simvastatin or lovastatin is not recommended due to an increased risk of myopathy including rhabdomyolysis.
Slovenian: Hkratna uporaba ritonavirja s simvastatinom ali lovastatinom zato ni priporočljiva, ker obstaja večje tveganje za miopatijo, vključno z rabdomiolizo.
English: Antifungal
Slovenian: Antiaritmiki
English: Ritonavir co-administration is likely to result in increased plasma concentrations of ergot derivatives and is therefore contraindicated (see section 4.3).
Slovenian: Sočasna uporaba ritonavirja ponavadi zviša koncentracijo derivatov ergot alkaloidov v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: Serum levels of ritonavir can be reduced by concomitant use of herbal preparations containing St John's wort (Hypericum perforatum).
Slovenian: Sočasna uporaba zdravil rastlinskega izvora, ki vsebujejo šentjanževko (Hypericum perforatum), lahko zmanjša koncentracijo ritonavirja v serumu, ker šentjanževka inducira encime, ki presnavljajo zdravila.
English: For further information, physicians should refer to the Summary of Product Characteristics for saquinavir.
Slovenian: Za dodatne informacije glejte povzetek glavnih značilnosti zdravila za sakvinavir.
English: Arthralgia and back pain Myositis, rhabdomyolysis, myalgia, myopathy/CPK increased
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva zelo pogosti artralgija in bolečine v hrbtu pogosti miozitis, rabdomioliza, mialgija, miopatija/zvišana CPK
English: Careful monitoring of therapeutic and adverse effects is recommended when dexamethasone is concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo deksametazona in ritonavirja je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov.
English: 400 q12 h Saquinavir4 Ritonavir
Slovenian: Sakvinavir4 ↑ 15-krat
English: 50, single dose 200q12h ↑ 2.4-fold ↑ 34% An increase in the incidence in trazodone-related adverse reactions was noted when co-administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Slovenian: Delavirdin1 ↔ ↔ Ritonavir ↑ 50 % ↑ 75 % Primerjava podatkov iz preteklosti ne kaže vpliva ritonavirja na farmakokinetiko delavirdina.
English: Careful monitoring of therapeutic and adverse effects is recommended when these medicines are concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo teh zdravil z ritonavirjem je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov.
English: Tipranavir 500 mg twice daily with ritonavir 200 mg twice daily.
Slovenian: Tipranavir 500 mg dvakrat na dan z ritonavirjem 200 mg dvakrat na dan (tipranavir z ritonavirjem naj se ne uporablja pri bolnikih, ki še niso bili zdravljeni z antiretrovirusno terapijo).
English: • laboratory test results: changes in blood test results (such as blood chemistry and blood count)
Slovenian: spremenjeni izvidi preiskav krvi
English: 4.4 Special warnings and precautions for use Ritonavir is not a cure for HIV-1 infection or AIDS.
Slovenian: Ritonavir ne ozdravi okužbe s HIV-1 ali AIDS-a.
English: Careful monitoring of therapeutic and adverse effects is recommended when loratadine is concomitantly administered with ritonavir.
Slovenian: Med sočasno uporabo loratidina in ritonavirja je priporočljivo natančno nadziranje terapevtskih in neželenih učinkov.
English: Barrier or other non-hormonal methods of contraception should be considered when administering ritonavir at therapeutic or low doses as ritonavir is likely to reduce the effect and change the uterine bleeding profile when co-administered with estradiol-containing contraceptives.
Slovenian: Ritonavir, uporabljen sočasno s kontraceptivi, ki vsebujejo estradiol, bo namreč verjetno zmanjšal njihov učinek in spremenil profil maternične krvavitve.
English: Due to an increased incidence of gastrointestinal and hepatic adverse reactions, a dose reduction of ketoconazole should be considered when co-administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Slovenian: Med sočasno uporabo ketokonazola in ritonavirja, odmerjanega kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, pride zaradi večje incidence neželenih učinkov na prebavila in jetra v poštev zmanjšanje odmerka ketokonazola.
English: Zidovudine
Slovenian: Prednizolon
English: Due to CYP3A inhibition by ritonavir, concentrations of quetiapine are expected to increase.
Slovenian: Zaradi zavrtja CYP3A z ritonavirjem, lahko pričakujemo zvišane koncentracije kvetiapina.
English: Darunavir 800 mg once daily with ritonavir 100 mg once daily may be used in some ART experienced patients.
Slovenian: Pri nekaterih bolnikih, ki so že bili zdravljeni z antiretrovirusno terapijo (ART), se lahko uporablja darunavir 800 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan. Za nadaljne informacije o uporabi darunavirja enkrat dnevno pri bolnikih, ki so že bili zdravljeni z antiretrovirusno terapijo, glejte povzetek glavnih značilnosti zdravila za darunavir.
English: Anti-infectives Fusidic acid
Slovenian: Direktno delujoča protivirusna zdravila proti HCV
English: 200 q12 h
Slovenian: 200 na 12 ur
English: 200 q12 h Tipranavir Ritonavir
Slovenian: ↑ 5-krat Ritonavir↔ ↔
English: See section 4.4 and section 4.5 for co-administration of sildenafil in patients with erectile dysfunction.
Slovenian: Glede sočasne uporabe sildenafila pri bolnikih z erektilno disfunkcijo glejte poglavji 4.4 in 4.5.
English: Amlodipine, diltiazem, nifedipine Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A4 and as a result is expected to increase the plasma concentrations of calcium channel antagonists.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A4, zato je treba pričakovati, da zviša koncentracijo antagonistov kalcijevih kanalčkov v plazmi.
English: Rivaroxaban
Slovenian: Levotiroksin
English: Ritonavir increases the serum levels of amprenavir (from fosamprenavir) as a result of CYP3A4 inhibition.
Slovenian: Ritonavir zavira CYP3A4 in tako zviša koncentracijo amprenavirja (iz fosamprenavirja) v serumu.
English: ↑ 86% ND
Slovenian: Ritonavir ↑ 17 %
English: Norpethidine metabolite
Slovenian: Presnovek norpetidina
English: Ritonavir increases the serum levels of nelfinavir as a result of CYP3A4 inhibition.
Slovenian: Ritonavir zavira CYP3A4 in tako zviša koncentracijo nelfinavirja v serumu.
English: Sorbitan laurate Silica, colloidal anhydrous Sodium chloride Sodium stearyl fumarate
Slovenian: Vsebina tablete: kopovidon sorbitan lavrat silicijev dioksid, koloidni, brezvodni natrijev klorid natrijev stearilfumarat
English: Ritonavir increases the serum levels of maraviroc as a result of CYP3A inhibition.
Slovenian: Ritonavir zavira CYP3A in tako zviša koncentracijo maraviroka v serumu.
English: Ritonavir increases the serum levels of tipranavir as a result of CYP3A inhibition.
Slovenian: Ritonavir zavira presnovo ketokonazola s CYP3A.
English: Minimal benefit of ritonavir-mediated pharmacokinetic enhancement is achieved with doses higher than 100 mg twice daily.
Slovenian: Z odmerki, višjimi od 100 mg dvakrat na dan, se farmakokinetično stopnjevanje z ritonavirjem le minimalno poveča.
English: 50, single dose 600q12h ↑ 13-fold ↑ 2.4-fold Concomitant use of avanafil with ritonavir is contraindicated (see section 4.3).
Slovenian: ↑ 2,4-krat Sočasna uporaba avanafila z ritonavirjem je kontraindicirana (glejte poglavje
English: 500q12h,↓ 36% ↓ 38% Increased methadone dose may be necessary when concomitantly administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer due to induction of glucuronidation.
Slovenian: 200 na 12h/1h prej 200 na 12h/ sočasno 200 na 12h/6h po Serumske koncentracije se lahko povečajo zaradi proteina odpornosti proti raku dojke (BCRP) in akutnega zavrtja P-gp z ritonavirjem.