FrancophonIA/ELRC3.0 huggingface dataset:
English: For patients with renal or hepatic impairment colchicine with boosted PREZISTA is contraindicated (see sections 4.3 and 4.4).
Slovenian: Pri bolnikih z ledvično ali jetrno okvaro je kombinacija kolhicina in okrepljenega zdravila PREZISTA kontraindicirana (glejte poglavji 4.3 in 4.4).
English: Even if you feel better, do not stop taking PREZISTA and cobicistat or ritonavir without talking to your doctor.
Slovenian: Tudi če se počutite bolje, ne smete prenehati z jemanjem zdravila PREZISTA in kobicistata ali ritonavirja, ne da bi se posvetovali s svojim zdravnikom.
English: The recommended dose regimen is 800 mg once daily with cobicistat 150 mg once daily or ritonavir 100 mg once daily taken with food.
Slovenian: Priporočeni režim odmerjanja zdravila PREZISTA je 800 mg enkrat na dan, skupaj s 150 mg kobicistata enkrat na dan ali s 100 mg ritonavirja enkrat na dan, s hrano.
English: PREZISTA should not be used in paediatric patients below 3 years of age or less than 15 kg body weight (see sections 4.4 and 5.3).
Slovenian: Zdravila PREZISTA se pri pediatričnih bolnikih, mlajših od 3 let ali s telesno maso, manjšo od 15 kg ne sme uporabljati (glejte poglavji 4.4 in 5.3).
English: Hepatobiliary disorders common increased alanine aminotransferase uncommon hepatitis, cytolytic hepatitis, hepatic steatosis, hepatomegaly, increased transaminase, increased aspartate aminotransferase, increased blood bilirubin, increased blood alkaline phosphatase, increased gamma-glutamyltransferase
Slovenian: občasni hepatitis, citolitični hepatitis, jetrna steatoza, hepatomegalija, povišana koncentracija transaminaz, povišanje koncentracije aspartat-aminotransferaze, povišana koncentracija bilirubina v krvi, povišana koncentracija alkalne fosfataze v krvi, povišana koncentracija gama-glutamiltransferaze
English: Plasma concentrations of these medicinal products may be increased when co-administered with boosted PREZISTA, resulting in reduced serum cortisol concentrations.
Slovenian: Ob sočasni uporabi z okrepljenim zdravilom PREZISTA se lahko plazemske koncentracije teh zdravil zvišajo, serumske koncentracije kortizola pa znižajo.
English: Excipient with known effect: Each tablet contains a maximum of 2.750 mg sunset yellow FCF (E110).
Slovenian: Pomožne snovi z znanim učinkom: Ena tableta vsebuje 2,750 mg barvila sončno rumeno FCF (E110).
English: Low rates of developing resistant HIV-1 virus were observed in ART-naïve patients who are treated for the first time with darunavir/cobicistat once daily in combination with other ART, and in ART-experienced patients with no darunavir RAMs receiving darunavir/cobicistat in combination with other ART.
Slovenian: Nizko stopnjo razvoja odpornih HIV-1 virusov so opazili pri bolnikih, ki niso imeli izkušenj z ART in so jih prvič zdravili s kombinacijo darunavir/kobicistat enkrat na dan skupaj z drugimi ART, in pri bolnikih z izkušnjami z ART brez RAM, ki so prejemali kombinacijo darunavir/kobicistat skupaj z drugimi ART. Spodnja preglednica prikazuje razvoj mutacij zaviralcev proteaze HIV-1 in odpornost za PI pri bolnikih z virološko odpovedjo v preskušanju GS-US-216-130.
English: Efavirenz in combination with PREZISTA/ritonavir 800/100 mg once daily may result in sub-optimal darunavir Cmin.
Slovenian: Pri uporabi kombinacije zdravil efavirenz in PREZISTA/ritonavir 800/100 mg enkrat na dan se Cmin darunavirja lahko zniža pod optimalno vrednost.
English: Concomitant use of sildenafil or tadalafil for the treatment of pulmonary arterial hypertension and darunavir co-administered with low dose ritonavir may increase plasma concentrations of sildenafil or tadalafil.
Slovenian: Pri sočasni uporabi sildenafila ali tadalafila (za zdravljenje pljučne arterijske hipertenzije) in darunavirja v kombinaciji z majhnim odmerkom ritonavirja lahko pride do zvišanja plazemskih koncentracij sildenafila ali tadalafila.
English: At 48 weeks, virologic response, defined as the percentage of patients with plasma HIV-1 RNA level < 50 copies/ml, with PREZISTA/ritonavir 800/100 mg once daily treatment was demonstrated to be non-inferior (at the pre-defined 12% non-inferiority margin) compared to PREZISTA/ritonavir 600/100 mg twice daily for both ITT and OP populations.
Slovenian: Po 48 tednih so dokazali, da je virološki odgovor, določen kot odstotek bolnikov, s plazemsko koncentracijo HIV-1 RNK < 50 kopij/ml, pri režimu zdravljenja z zdravilom PREZISTA/ritonavir 800/100 mg enkrat na dan primerljiv (pri v naprej določeni meji primerljivosti 12%) z režimom PREZISTA/ritonavir 600/100 mg dvakrat na dan tako pri tako ITT, kot tudi pri OP populaciji bolnikov.
English: Therefore the same once daily dosage may be used in treatment-experienced adolescents aged 12 to < 18 years and weighing at least 40 kg without darunavir resistance associated mutations (DRV-RAMs)* and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Slovenian: Zato se lahko enako enkrat dnevno odmerjanje uporabi pri mladostnikih, starih 12 do < 18 let in s telesno maso najmanj 40 kg, z izkušnjami z zdravljenjem, ki nimajo z rezistenco za darunavir povezanih mutacij (DRV-RAM) * in imajo plazemsko koncentracijo HIV-1 RNK < 100.000 kopij/ml in število CD4+ celic ≥ 100 celic x 10
English: PREZISTA tablets contain sunset yellow FCF (E110) which may cause allergic reactions.
Slovenian: Prezista tablete vsebujejo barvilo sončno rumeno FCF (E110), ki lahko povzroči alergijske reakcije.
English: 240 tablets in a plastic bottle.
Slovenian: 240 tablet v plastičnem vsebniku.
English: In addition, pharmacokinetic modeling and simulation of darunavir exposures in paediatric patients across the ages of 3 to < 18 years confirmed the darunavir exposures as observed in the clinical studies and allowed the identification of weight-based PREZISTA/ritonavir once daily dosing regimens for paediatric patients weighing at least 15 kg that are either ART-naïve or treatment-experienced paediatric patients without DRV-RAMs* and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Slovenian: Farmakokinetični model in posnemanje izpostavljenosti darunavirju pri pediatričnih bolnikih starih 3 do< 18 let sta potrdila izpostavljenost darunavirju, opaženo v kliničnih preskušanjih in na osnovi telesne mase določila odmerjanje zdravil PREZISTA/ritonavir enkrat na dan pri pediatričnih bolnikih s telesno maso najmanj 15 kg, ki še nimajo ali pa že imajo izkušnje ART in so brez z rezistenco za darunavir povezanih mutacij (DRV-RAM) * in imajo plazemsko koncentracijo HIV-1 RNK < 100.000 kopij/ml in število CD4+ celic ≥ 100 celic x 10
English: Orange oval shaped tablet of 17.3 mm, debossed with “300MG” on one side and “TMC114” on the other side.
Slovenian: Oranžna ovalna tableta, dolga 17,3 mm, z vtisnjeno oznako “300MG” na eni strani in “TMC114” na drugi.
English: (↑ clarithromycin from CYP3A inhibition and possible P-gp inhibition)
Slovenian: (↑ koncentracij klaritromicina zaradi zaviranja CYP3A in verjetno tudi P-gp)
English: ART-experienced paediatric patients (3 to 17 years of age and weighing at least 40 kg) In ART-experienced patients without DRV-RAMs* and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Slovenian: Pediatrični bolniki,ki imajo izkušnje z ART (stari 3 do 17 let in s telesno maso najmanj 40 kg) Pri bolnikih z izkušnjami z ART, ki nimajo DRV-RAM * in imajo plazemsko koncentracijo HIV-1 RNK < 100.000 kopij/ml in število CD4+ celic ≥ 100 celic x 10
English: Interaction Geometric mean change (%)
Slovenian: Medsebojno delovanje Geometrična povprečna sprememba
English: OR - 800 milligram PREZISTA together with 150 milligram cobicistat or100 milligram ritonavir once daily.
Slovenian: ALI - 800 miligramov zdravila PREZISTA skupaj s 150 miligrami kobicistata ali s 100 miligrami ritonavirja enkrat na dan.
English: PREZISTA 400 mg film-coated tablets 3 years
Slovenian: PREZISTA 400 mg filmsko obložene tablete 3 leta
English: The PREZISTA 400 milligram tablet is not for use in children younger than 3 years of age or weighing less than 40 kilograms.
Slovenian: Zdravila PREZISTA 400 miligramov se ne sme uporabljati pri otrocih, mlajših od 3 let ali s telesno maso manj kot 15 kg.
English: Insert the supplied oral dosing pipette all the way into the bottle.
Slovenian: Priloženo merilno kapalko vstavite v steklenico.
English: This dose must not exceed the recommended adult dose, which is 600 milligram PREZISTA together with 100 milligram of ritonavir two times per day or 800 milligram PREZISTA together with 100 milligram ritonavir once a day.
Slovenian: Ta odmerek ne sme preseči priporočenega odmerka za odrasle, ki je 600 miligramov zdravila PREZISTA, skupaj s 100 miligrami ritonavirja, dvakrat na dan ali 800 miligramov zdravila PREZISTA, skupaj s 100 miligrami ritonavirja, enkrat na dan.
English: Buprenorphine/naloxone 8/2 mg-16/4 mg once daily buprenorphine AUC ↓ 11% buprenorphine Cmin ↔ buprenorphine Cmax ↓ 8% norbuprenorphine AUC ↑ 46% norbuprenorphine Cmin ↑ 71% norbuprenorphine Cmax ↑ 36% naloxone AUC ↔ naloxone Cmin ND naloxone Cmax ↔
Slovenian: buprenorfin/nalokson 8/2 mg-16/4 mg enkrat na dan buprenorfin AUC ↓ 11% buprenorfin Cmin ↔ buprenorfin Cmax ↓ 8% norbuprenorfin AUC ↑ 46% norbuprenorfin Cmin ↑ 71% norbuprenorfin Cmax ↑ 36% nalokson AUC ↔ nalokson Cmin ND nalokson Cmax ↔
English: • 80 ART-experienced HIV-1 infected paediatric patients aged from 6 to 17 years and weighing at least 20 kg who received PREZISTA tablets with low dose ritonavir twice daily in combination with other antiretroviral agents.
Slovenian: • 80 s HIV-1 okuženih pediatričnih bolnikov, starih 6 do 17 let in s telesno maso najmanj 20 kg, z izkušnjami z ART, ki so prejemali zdravilo PREZISTA skupaj z majhnim odmerkom ritonavirja dvakrat na dan in drugimi protiretrovirusnimi zdravili.
English: Renal impairment No dose adjustment is required in patients with renal impairment (see sections 4.4 and 5.2).
Slovenian: Okvara ledvic Pri bolnikih z okvaro ledvic prilagajanje odmerka ni potrebno (glejte poglavji 4.4 in 5.2).
English: Children PREZISTA is not for use in children younger than 3 years of age or weighing less than 15 kilograms.
Slovenian: Zdravila PREZISTA se pri otrocih, ki so mlajši od 3 let ali imajo telesno maso manjšo od 15 kilogramov, ne sme uporabljati.
English: Efavirenz in combination with boosted PREZISTA once daily may result in sub-optimal darunavir Cmin.
Slovenian: Pri uporabi kombinacije efavirenz in okrepljenega zdravila PREZISTA enkrat na dan se Cmin darunavirja lahko zniža pod optimalno vrednost.
English: The PREZISTA 800 milligram tablet is used to treat adults and children (3 years of age and above, at least 40 kilograms body weight) who are infected by HIV and - who have not used antiretroviral medicines before.
Slovenian: Zdravilo PREZISTA 800 miligramov uporabljamo za zdravljenje odraslih in otrok (starih 3 leta ali starejših in s telesno maso najmanj 40 kg), ki so okuženi z virusom HIV in - še niso prejemali nobenega drugega protiretrovirusnega zdravila.
English: b PREZISTA/100 mg (1.2 ml) ritonavir once daily
Slovenian: b PREZISTA/100 mg (1,2 ml) ritonavir enkrat na dan
English: Instructions for adults - Take PREZISTA always together with cobicistat or ritonavir.
Slovenian: Navodila za odrasle - Zdravilo PREZISTA jemljite vedno skupaj s kobicistatom ali z ritonavirjem.
English: The recommended dose regimen is 600 mg twice daily taken with ritonavir 100 mg twice daily taken with food.
Slovenian: Priporočeno je odmerjanje 600 mg darunavirja dvakrat na dan, skupaj s 100 mg ritonavirja dvakrat na dan, s hrano.
English: With baseline HIV-RNA
Slovenian: z začetno HIV-RNK
English: Metabolism and nutrition disorders common diabetes mellitus, hypertriglyceridaemia, hypercholesterolaemia, hyperlipidaemia uncommon gout, anorexia, decreased appetite, decreased weight, increased weight, hyperglycaemia, insulin resistance, decreased high density lipoprotein, increased appetite, polydipsia, increased blood lactate dehydrogenase
Slovenian: Presnovne in prehranske motnje pogosti sladkorna bolezen, hipertrigliceridemija, hiperholesterolemija, hiperlipidemija občasni protin, anoreksija, zmanjšan tek, zmanjšana telesna masa, zvečana telesna masa, hiperglikemija, odpornost na insulin, znižana koncentracija lipoproteinov visoke gostote, zvečan tek, polidipsija, povišana koncentracija laktat-dehidrogenaze v krvi
English: Exposure to these immunosuppressants will be increased when co-administered with PREZISTA co-administered with low dose ritonavir.
Slovenian: Pričakovano je zvečanje izpostavljenosti navedenim imunosupresivom pri njihovi sočasni uporabi z zdravilom PREZISTA skupaj z majhnim odmerkom ritonavirja.
English: PREZISTA cannot work properly without food.
Slovenian: PREZISTA ne more pravilno delovati.
English: The recommended dose of emtricitabine/tenofovir alafenamide is 200/10 mg once daily when used with boosted PREZISTA.
Slovenian: Priporočeni odmerek emtricitabin/alafenamidtenofovirata v kombinaciji z okrepljenim zdravilom PREZISTA je 200/10 mg enkrat na dan.
English: For dosage recommendations in ART-naïve patients see the Summary of Product Characteristics for PREZISTA 400 mg and 800 mg tablets.
Slovenian: Priporočila za odmerjanje pri bolnikih, ki še nimajo izkušenj z ART, so navedena v Povzetku glavnih značilnosti zdravil PREZISTA 400 mg in 800 mg tablete.
English: If antidepressants are co-administered with PREZISTA with low dose ritonavir, the recommended approach is a dose titration of the antidepressant based on a clinical assessment of antidepressant response.
Slovenian: Pri sočasni uporabi antidepresivov in zdravila PREZISTA skupaj z majhnim odmerkom ritonavirja, se priporoča titracija odmerka antidepresiva na podlagi klinične ocene učinka antidepresiva.
English: For dosage recommendations in children, see the Summary of Product Characteristics for PREZISTA 75 mg, 150 mg, 300 mg, 600 mg tablets and 100 mg/ml oral suspension.
Slovenian: Navodila za odmerjanje pri otrocih so navedena v Povzetkih glavnih značilnosti zdravil PREZISTA 75 mg, 150 mg, 300 mg, 600 mg tablete in 100 mg/ml peroralni suspenziji.
English: White oval shaped tablet of 13.7 mm, debossed with “150” on one side and “TMC” on the other side.
Slovenian: Bela ovalna tableta, dolga 13,7 mm, z vtisnjeno oznako “150” na eni strani in “TMC” na drugi.
English: PREZISTA is not recommended for use in paediatric patients below 3 years of age or less than 15 kg body weight (see sections 4.2 and 5.3).
Slovenian: Uporaba zdravila PREZISTA pri pediatričnih bolnikih, mlajših od 3 let ali s telesno maso manjšo od 15 kg ni priporočljiva (glejte poglavji 4.2 in 5.3).
English: At 48 weeks non-inferiority in virologic response to the PREZISTA/ritonavir treatment, defined as the percentage of patients with plasma HIV-1 RNA level < 400 and < 50 copies/ml, was demonstrated (at the pre-defined 12% non-inferiority margin) for both ITT and OP populations.
Slovenian: Po 48 tednih zdravljenja z zdravilom PREZISTA/ritonavir so primerljivost virološkega odziva, ki je določena kot odstotek bolnikov s koncentracijo HIV-1 RNK v plazmi < 400 kopij/ml in < 50 kopij, dokazali (pri predhodno določeni 12% meji primerljivosti) tako za ITT, kot tudi za OP populacijo bolnikov.
English: If parenteral midazolam is co-administered with boosted PREZISTA it may cause a large increase in the concentration of this benzodiazepine.
Slovenian: Sočasna uporaba parenteralnega midazolama in okrepljenega zdravila PREZISTA lahko povzroči veliko zvišanje koncentracije tega benzodiazepina.
English: Nervous system disorders common headache, peripheral neuropathy, dizziness uncommon lethargy, paraesthesia, hypoaesthesia, dysgeusia, disturbance in attention, memory impairment, somnolence rare syncope, convulsion, ageusia, sleep phase rhythm disturbance
Slovenian: Bolezni živčevja pogosti glavobol, periferna nevropatija, omotica občasni letargija, parestezija, hipestezija, disgevzija, motnje pozornosti redki sinkopa, konvulzije, agevzija, motnje spalnega ritma
English: This dose must not exceed the recommended adult dose, which is 800 milligram PREZISTA together with 100 milligram ritonavir once a day.
Slovenian: Ta odmerek ne sme preseči priporočenega odmerka za odrasle, ki je 800 miligramov zdravila PREZISTA skupaj s 100 miligrami ritonavirja, enkrat na dan.
English: Nevirapine 200 mg twice daily nevirapine AUC ↑ 27% nevirapine Cmin ↑ 47% nevirapine Cmax ↑ 18% darunavir: concentrations were consistent with historical data (↑ nevirapine from CYP3A inhibition)
Slovenian: nevirapin 200 mg dvakrat na dan nevirapin AUC ↑ 27% nevirapin Cmin ↑ 47% nevirapin Cmax ↑ 18% koncentracije darunavirja so bile skladne s starejšimi podatki.
English: - The other ingredients are microcrystalline cellulose, colloidal anhydrous silica, crospovidone, magnesium stearate.
Slovenian: - Druge sestavine zdravila so mikrokristalna celuloza, koloidni brezvodni silicijev dioksid, krospovidon, magnezijev stearat.
English: PREZISTA 75 mg film-coated tablets Each film-coated tablet contains 75 mg of darunavir (as ethanolate).
Slovenian: PREZISTA 75 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 75 mg darunavirja (v obliki etanolata).
English: PREZISTA co-administered with low dose ritonavir can be co-administered with H2-receptor antagonists without dose adjustments.
Slovenian: Zdravilo PREZISTA z majhnim odmerkom ritonavirja lahko uporabljamo sočasno z antagonisti receptorjev H2, brez prilagajanja odmerka.
English: Orange oval shaped tablet of 21.1 mm, debossed with “600MG” on one side and “TMC” on the other side.
Slovenian: Oranžna ovalna tableta, dolga 21,1 mm, z vtisnjeno oznako “600MG” na eni strani in “TMC” na drugi.
English: PREZISTA 800 mg film-coated tablets 2 years
Slovenian: PREZISTA 800 mg filmsko obložene tablete 2 leti
English: Patients should be instructed to take PREZISTA with cobicistat or low dose ritonavir within 30 minutes after completion of a meal.
Slovenian: Bolnike je treba poučiti, da najkasneje v 30 minutah po obroku vzamejo zdravilo PREZISTA skupaj s kobicistatom ali z majhnim odmerkom ritonavirja.
English: Hepatobiliary disorders common hepatic enzyme increased uncommon hepatitis*, cytolytic hepatitis*
Slovenian: Bolezni jeter, žolčnika in žolčevodov pogosti zvišane vrednosti jetrnih encimov občasni hepatitis*, citolitični hepatitis*
English: This cannot be administered with these 600 milligram tablets.
Slovenian: Ta odmerek se ne da doseči s 600 -miligramskimi tabletami.
English: Based on theoretical considerations PREZISTA is expected to increase alfuzosin plasma concentrations.
Slovenian: Po teoretični presoji se pri sočasni uporabi zdravila PREZISTA z alfuzosinom pričakuje zvišanje plazemskih koncentracij.
English: prezista 150 mg (this is only applicable to the outer pack)
Slovenian: prezista 150 mg (nanaša se samo na zunanjo ovojnino)
English: For clinical trial results in ART-naïve paediatric patients aged 12 to 17 years, refer to the Summary of Product Characteristics for PREZISTA 400 mg and 800 mg tablets or PREZISTA 100 mg/ml oral suspension.
Slovenian: Za rezultate kliničnih preskušanj pri bolnikih, ki nimajo izkušenj z ART, starih 12 do 17 let, glejte Povzetke glavnih značilnosti zdravil PREZISTA 400 mg in 800 mg tablete in PREZISTA 100 mg/ml peroralna suspenzija.
English: The PREZISTA 400 milligram tablet is used to treat adults and children (3 years of age and above, at least 40 kilograms body weight) who are infected by HIV and - who have not used antiretroviral medicines before.
Slovenian: Zdravilo PREZISTA 400 miligramov uporabljamo za zdravljenje odraslih in otrok (starih 3 leta ali starejših in s telesno maso najmanj 40 kg), ki so okuženi z virusom HIV in - še niso prejemali nobenega drugega protiretrovirusnega zdravila.
English: Saquinavir 1,000 mg twice daily darunavir AUC ↓ 26% darunavir Cmin ↓ 42% darunavir Cmax ↓ 17% saquinavir AUC ↓ 6% saquinavir Cmin ↓ 18% saquinavir Cmax ↓ 6%
Slovenian: sakvinavir 1.000 mg dvakrat na dan darunavir AUC ↓ 26% darunavir Cmin ↓ 42% darunavir Cmax ↓ 17%
English: White caplet shaped tablet of 9.2 mm, debossed with “75” on one side and “TMC” on the other side.
Slovenian: Bela ovalna tableta, dolga 9,2 mm, z vtisnjeno oznako “75” na eni strani in “TMC” na drugi.
English: Co-administration of PREZISTA co-administered with cobicistat and rifabutin is not recommended.
Slovenian: Sočasna uporaba zdravila PREZISTA s kobicistatom in rifabutinom ni priporočljiva.
English: 380 mg (3.8 ml) PREZISTA/50 mg (0.6 ml) ritonavir twice daily
Slovenian: 380 mg (3.8 ml) PREZISTA/50 mg (0,6 ml) ritonavir dvakrat na dan
English: kidney or lung] - heart attack, slow heart beating, palpitations - visual disturbance - chills, feeling abnormal - a feeling of confusion or disorientation, altered mood, restlessness - fainting, epileptic fits, changes or loss of taste - mouth sores, vomiting blood, inflamation of the lips, dry lips, coated tongue - running nose - skin lesions, dry skin - stiffness of muscles or joints, joint pain with or without inflammation - changes in some values of your blood cells or chemistry.
Slovenian: - mrzlica, nenavadno počutje - stanje zmedenosti ali dezorientacije, spremembe razpoloženja, nemir - omedlevica, epileptični napadi, spremembe ali izguba okusa - razjede v ustih, bruhanje krvi, vnetje ustnic, suha usta, obložen jezik - izcedek iz nosu - razjede na koži, suha koža - okorelost mišic ali sklepov, bolečina v sklepih z vnetjem ali brez vnetja - spremembe v vrednostih nekaterih krvnih celic ali kemijskih parametrov.
English: 30 tablets in a plastic bottle.
Slovenian: 30 tablet v plastičnem vsebniku.
English: PREZISTA 75 mg film-coated tablets
Slovenian: PREZISTA 75 mg filmsko obložene tablete
English: Human experience of acute overdose with PREZISTA co-administered with cobicistat or low dose ritonavir is limited.
Slovenian: Izkušnje z akutnim prevelikim odmerjanjem zdravila PREZISTA skupaj s kobicistatom ali z majhnim odmerkom ritonavirja pri ljudeh so omejene.
English: PREZISTA contains the active substance darunavir.
Slovenian: Zdravilo PREZISTA vsebuje zdravilno učinkovino darunavir.
English: Removing the child resistant cap The plastic bottle comes with a child resistant cap and must be opened as follows: Push the plastic screw cap down while turning it counter clockwise.
Slovenian: Snemanje zaporke, varne za otroke Plastenka ima za otroke varno zaporko, ki jo odprete takole: Potisnite plastično navojno zaporko navzdol in jo pri tem obračajte v nasprotni smeri urinega kazalca.
English: Do not combine PREZISTA with products that contain St John's wort (Hypericum perforatum).
Slovenian: Zdravila PREZISTA ne smete jemati sočasno z zdravili rastlinskega izvora, ki vsebujejo šentjanževko (Hypericum perforatum).
English: Co-administration of boosted PREZISTA with clonazepam may increase concentrations of clonazepam.
Slovenian: Sočasna uporaba okrepljenega zdravila PREZISTA s klonazepamom lahko zviša koncentracije klonazepama.
English: Based on theoretical considerations PREZISTA co-administered with cobicistat is expected to increase metformin plasma concentrations.
Slovenian: Po teoretični presoji se pri sočasni uporabi zdravila PREZISTA s kobicistatom pričakuje zvišanje plazemskih koncentracij metformina.
English: Instructions for children 3 years of age and above, weighing more than 40 kilograms - Take 800 milligram PREZISTA (2 tablets containing 400 milligram of PREZISTA or 1 tablet containing 800 milligram of PREZISTA) at the same time, once a day, every day.
Slovenian: Navodila za otroke, stare 3 leta in več, s telesno maso najmanj 40 kg - Vzemite 800 miligramov zdravila PREZISTA (2 tableti zdravila PREZISTA po 400 miligramov ali 1 tableta zdravila PREZISTA po 800 miligramov) vsak dan ob istem času, enkrat na dan. - Zdravilo PREZISTA vzemite vedno skupaj s 100 miligrami ritonavirja.