FrancophonIA/ELRC3.0 huggingface dataset:
English: Darunavir Cmax: ↔ 0.96 Darunavir C12: ↓ 0.77
Slovenian: Darunavir AUC12: ↓ 0,86 Darunavir Cmax: ↔ 0,96 Darunavir C12: ↓ 0,77
English: Use the oral applicator supplied with the pack to measure your dose accurately.
Slovenian: Za točno odmerjanje odmerka uporabite aplikator za peroralno odmerjanje, ki je priložen v pakiranju.
English: Maraviroc 300 mg twice daily + OBT N=426
Slovenian: Maravirok 300 mg dvakrat na dan + OOT n = 426
English: If you notice any of these symptoms: Tell your doctor.
Slovenian: Če se vam pojavijo ti simptomi, nemudoma obvestite zdravnika.
English: These include:  symptoms of infections and inflammation  joint pain, stiffness and bone problems.
Slovenian:  simptomi okužb in vnetja,  bolečine v sklepih, togost sklepov in težave s kostmi.
English: Lamivudine Cmax: ↔ 1.16
Slovenian: Lamivudin Cmax: ↔ 1,16
English: Ketoconazole concentrations not measured, no effect is expected.
Slovenian: Koncentracija ketokonazola ni bila merjena, učinki niso pričakovani.
English: Maraviroc is the major circulating component (approximately 42% radioactivity) following a single oral dose of 300 mg.
Slovenian: Po posamičnem peroralnem odmerku 300 mg je maravirok glavna komponenta v obtoku (približno 42 % radioaktivnosti).
English: Hepatic disease
Slovenian: Bolezni jeter
English: Etravirine C12: ↔ 1.08
Slovenian: Etravirin C12: ↔ 1,08
English: Poly (vinyl alcohol) Titanium dioxide (E171) Macrogol 3350
Slovenian: Filmska obloga polivinilalkohol titanov dioksid (E171) makrogol 3350 smukec sojin lecitin indigotin (E132)
English: Dialysis had a minimal effect on exposure in subjects with ESRD.
Slovenian: Dializa je pri bolnikih s končno odpovedjo ledvic minimalno vplivala na izpostavljenost.
English: More patients treated with maraviroc discontinued due to lack of efficacy (43 vs.15) and among patients with lack of efficacy, the proportion acquiring NRTI resistance (mainly lamivudine) was higher in the maraviroc arm.
Slovenian: Med bolniki z nezadostno učinkovitostjo je bil delež s pridobljeno odpornostjo za nukleozidne zaviralce reverzne transkriptaze (predvsem za lamivudin) večji v kraku z maravirokom.
English: CELSENTRI should be used with caution in adult patients with severe renal impairment (CLcr <30 mL/min) who are receiving potent CYP3A4 inhibitors (see sections 4.4 and 5.2).
Slovenian: Pri odraslih bolnikih s hudo okvaro ledvic (očistek kreatinina < 30 ml/min), ki jemljejo močne zaviralce CYP3A4, je treba zdravilo CELSENTRI uporabljati previdno (glejte poglavji 4.4 in 5.2).
English: Anti-HCV Ribavirin
Slovenian: Zdravila proti hepatitisu C Ribavirin
English: CELSENTRI 300 mg film-coated tablets
Slovenian: CELSENTRI 300 mg filmsko obložene tablete
English: ANTIBIOTICS Sulphamethoxazole/ Trimethoprim 800 mg/160 mg BID (maraviroc 300 mg BID)
Slovenian: ANTIBIOTIKI Sulfametoksazol/ trimetoprim 800 mg/160 mg dvakrat na dan (maravirok 300 mg dvakrat na dan)
English: CELSENTRI 75 mg film-coated tablets
Slovenian: CELSENTRI 75 mg filmsko obložene tablete
English: Maraviroc AUC12: ↔ 1.11
Slovenian: Maravirok AUC12: ↔ 1,11
English: Nevirapine 200 mg BID (maraviroc 300 mg Single Dose)
Slovenian: Nevirapin 200 mg dvakrat na dan (maravirok 300 mg enkraten odmerek)
English: An increased risk of postural hypotension may occur in patients with severe renal insufficiency who are treated with potent CYP3A inhibitors or boosted protease inhibitors (PIs) and maraviroc.
Slovenian: Bolniki s hudo insuficienco ledvic, ki dobivajo močne zaviralce CYP3A ali okrepljene zaviralce proteaz in maravirok, imajo lahko večje tveganje posturalne hipotenzije.
English: Sulphamethoxazole/trimethoprim concentrations not measured, no effect expected.
Slovenian: Koncentraciji sulfametoksazola/trimetoprima nista bili merjeni, učinki niso pričakovani.
English: Not studied, but both are potent CYP3A4 inhibitors and would be expected to increase maraviroc concentrations.
Slovenian: Ni raziskano; ker pa sta oba močna zaviralca CYP3A4, je mogoče pričakovati zvišanje koncentracije maraviroka.
English: Each ml of oral solution contains 20 mg maraviroc.
Slovenian: En mililiter peroralne raztopine vsebuje 20 mg maraviroka.
English: Zidovudine AUC12: ↔ 0.98
Slovenian: Zidovudin AUC12: ↔ 0,98
English: Abdominal pain, flatulence, nausea common
Slovenian: Bolezni prebavil bolečine v trebuhu, flatulenca, navzea pogosti
English: celsentri 20 mg/ml
Slovenian: PODATKI V BRAILLOVI PISAVI celsentri 20 mg/ml
English: Background resistance to other classes of antiretrovirals have been shown to be similar in previously undetected CXCR4-tropic virus of the minor viral population, as that found in CCR5-tropic virus.
Slovenian: Ugotovljeno je, da je odpornost predhodno neodkritih CXCR4-tropnih virusov iz manjšinske virusne populacije proti drugim skupinam protiretrovirusnih zdravil podobna kot odpornost CCR5-tropnih virusov.
English: Other developmental parameters of these offspring, including fertility and reproductive performance, were not affected by the maternal administration of maraviroc.
Slovenian: Uporaba maraviroka pri samicah materah ni vplivala na druge razvojne parametre tega potomstva, vključno s plodnostjo in spodobnostjo razmnoževanja.
English: Maraviroc AUC12: ↑ 2.53
Slovenian: Maravirok AUC12: ↑ 2,53
English: • The other ingredients are: citric acid (anhydrous), sodium citrate dihydrate, sucralose, sodium benzoate, strawberry flavouring (501440T), purified water
Slovenian: • Druge sestavine zdravila so: citronska kislina (brezvodna), natrijev citrat dihidrat, sukraloza,
English: Maraviroc AUC12: ↓ 0.55
Slovenian: Maravirok AUC12: ↓ 0,55
English: CD4+ cell count Mean change from baseline (cells/µL) 1 p-values < 0.0001 2 For all efficacy endpoints the confidence intervals were 95%, except for HIV-1 RNA Change from baseline, which was 97.5%
Slovenian: Intervali zaupanja so bili za vse primarne cilje učinkovitosti 95 %, za spremembo HIV-1 RNA od izhodišča pa 97,5 %.
English: Maraviroc Cmax: ↑ 2.09
Slovenian: Maravirok Cmax: ↑ 2,09
English: CXCR4-using virus was detected at failure in approximately 60% of subjects who failed treatment on maraviroc, as compared to 6% of subjects who experienced treatment failure in the placebo + OBT arm. To investigate the likely origin of the on-treatment CXCR4-using virus, a detailed clonal analysis was conducted on virus from 20 representative subjects (16 subjects from the maraviroc arms and 4 subjects from the placebo + OBT arm) in whom CXCR4-using virus was detected at treatment failure.
Slovenian: Da bi raziskali verjetni izvir virusa uporabnika CXCR4 med zdravljenjem, so opravili podrobno klonsko analizo virusov 20 reprezentativnih preiskovancev (16 preiskovancev iz kraka z maravirokom in 4 preiskovancev iz kraka s placebom + OOT), pri katerih so ob neuspehu terapije ugotovili virus uporabnik CXCR4.
English: Postural hypotension (see section 4.4) uncommon
Slovenian: Žilne bolezni posturalna hipotenzija (glejte poglavje 4.4)
English: 2x carton for blister pack containing 300 mg maraviroc film-coated tablets - without Blue Box
Slovenian: PODATKI NA ZUNANJI OVOJNINI 2× škatla za pretisne omote s 300 mg filmsko obloženimi tabletami - brez blue box
English: Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Efavirenz 600 mg QD (maraviroc 100 mg BID)
Slovenian: Nenukleozidni zaviralci reverzne transkriptaze (NNRTI) Efavirenz 600 mg enkrat na dan (maravirok 100 mg dvakrat na dan)
English: Check with your doctor if you think this applies to you or your child.
Slovenian: Pred začetkom zdravljenja se posvetujte z zdravnikom, če mislite, da se kaj od naštetega nanaša na vas (ali na vašega otroka).
English: Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs) Lamivudine 150 mg BID (maraviroc 300 mg BID)
Slovenian: Zaviralci nukleozidne in nukleotidne reverzne transkriptaze (NRTI) Lamivudin 150 mg dvakrat na dan (maravirok 300 mg dvakrat na dan)
English: 2x carton for blister pack containing 150 mg maraviroc film-coated tablets - without Blue Box
Slovenian: PODATKI NA ZUNANJI OVOJNINI 2× škatla za pretisne omote s 150 mg filmsko obloženimi tabletami - brez blue box
English: Hepatitis toxic, hepatic failure, hepatic cirrhosis, blood alkaline phosphatase increased rare
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva miozitis, zvišanje kreatin-fosfokinaze v krvi občasni atrofija mišic redki
English: Therefore, unless your doctor tells you (or your child) to stop treatment, it is important to keep taking CELSENTRI correctly, as described above.
Slovenian: Zato je pomembno, da zdravilo CELSENTRI jemljete pravilno, tako kot je opisano zgoraj, razen če vam (ali vašemu otroku) zdravnik naroči, da morate zdravljenje prekiniti.
English: >2.0x ULN
Slovenian: > 2,0 x ZNM 4,9
English: Store the oral solution below 30°C.
Slovenian: Peroralno raztopino shranjujte pri temperaturi do 30 °C.
English: Maraviroc Cmax: ↔ 1.19
Slovenian: Maravirok Cmax: ↔ 1,19
English: The highest dose administered in clinical studies was 1,200 mg.
Slovenian: Največji aplicirani odmerek v kliničnih študijah je bil 1.200 mg. Neželeni učinek, ki je omejeval odmerek, je bila posturalna hipotenzija.
English: Efavirenz 600 mg QD + saquinavir/ritonavir 1000 mg/100 mg BID (maraviroc 100 mg BID)
Slovenian: Efavirenz 600 mg enkrat na dan + sakvinavir/ritonavir 1000 mg/100 mg dvakrat na dan (maravirok 100 mg dvakrat na dan)
English: Maraviroc Cmax: ↑ 3.38
Slovenian: Maravirok Cmax: ↑ 3,38
English: Maraviroc Cmax: ↑ 4.78
Slovenian: Maravirok Cmax: ↑ 4,78
English: CELSENTRI dose should be decreased to 150 mg twice daily when co-administered with efavirenz and a PI (except tipranavir/ritonavir where the dose should be 600 mg twice daily).
Slovenian: Če je zdravilo CELSENTRI uporabljeno sočasno z efavirenzom in zaviralcem proteaz, je treba njegov odmerek zmanjšati na 150 mg dvakrat na dan (izjema je sočasna uporaba s tipranavirjem/ritonavirjem, kjer mora biti odmerek 600 mg dvakrat na dan).
English: CELSENTRI can make you dizzy.
Slovenian: Zdravilo CELSENTRI lahko povzroči omotico.
English: Discontinue maraviroc and other suspect agents immediately if signs or symptoms of severe skin or hypersensitivity reactions develop.
Slovenian: Če se pojavijo znaki ali simptomi hudih kožnih ali preobčutljivostnih reakcij, nemudoma nehajte uporabljati maravirok in druga sumljiva zdravila.
English: CELSENTRI 25 mg film-coated tablets
Slovenian: CELSENTRI 25 mg filmsko obložene tablete
English: Maraviroc Cmax: ↑ 1.25
Slovenian: Maravirok Cmax: ↑ 1,25
English: Blue, biconvex, oval film-coated tablets, approximate dimensions 8.56 mm x 15.5 mm and debossed with “MVC 150”.
Slovenian: Modra, bikonveksna, ovalna filmsko obložena tableta, velika približno 8,56 mm x 15,5 mm z oznako "MVC 150".
English: Excipient with known effect: each 75 mg film-coated tablet contains 0.42 mg of soya lecithin.
Slovenian: Pomožne snovi z znanim učinkom: ena 75 mg filmsko obložena tableta vsebuje 0,42 mg sojinega lecitina.
English: CELSENTRI 150 mg film-coated tablets
Slovenian: CELSENTRI 150 mg filmsko obložene tablete
English: Dose adjustment is necessary in patients with renal impairment receiving maraviroc with potent CYP3A4 inhibitors (see sections 4.2 and 4.4 and 4.5).
Slovenian: Bolnikom z okvaro ledvic, ki dobivajo maravirok z močnimi zaviralci CYP3A4, je treba odmerek prilagoditi (glejte poglavje 4.2, 4.4 in 4.5).
English: Each film-coated tablet contains 300 mg of maraviroc.
Slovenian: Ena filmsko obložena tableta vsebuje 300 mg maraviroka.
English: Maraviroc Cmax: ↑ 1.97
Slovenian: Maravirok Cmax: ↑ 1,97
English: How to store CELSENTRI Contents of the pack and other information
Slovenian: Vsebina pakiranja in dodatne informacije
English: Tenofovir concentrations not measured, no effect is expected.
Slovenian: Koncentracija tenofovirja ni bila merjena, učinki niso pričakovani.
English: Maraviroc Cmax: ↔ 1.03
Slovenian: Maravirok Cmax: ↔ 1,03
English: SEDATIVES
Slovenian: Dojenje
English: Tipranavir/ritonavir 500 mg/200 mg BID (maraviroc 150 mg BID)
Slovenian: Tipranavir/ritonavir 500 mg/200 mg dvakrat na dan (maravirok 150 mg dvakrat na dan)
English: celsentri 300 mg
Slovenian: PODATKI V BRAILLOVI PISAVI celsentri 300 mg
English: At the time of failure with CXCR4-using virus, the resistance pattern to other antiretrovirals appears similar to that of the CCR5-tropic population at baseline, based on available data.
Slovenian: Na podlagi razpoložljivih podatkov kaže, da je ob neuspehu z virusom uporabnikom CXCR4 odpornost proti drugim protiretrovirusnim zdravilom podobna kot izhodiščno v CCR5-tropni populaciji.
English: Zidovudine Cmax: ↔ 0.92
Slovenian: Zidovudin Cmax: ↔ 0,92
English: Each film-coated tablet contains 75 mg of maraviroc.
Slovenian: Ena filmsko obložena tableta vsebuje 75 mg maraviroka.
English: GENERAL CLASSIFICATION FOR SUPPLY 15.
Slovenian: Shranjevanje zdravila CELSENTRI 6.
English: Blue, biconvex, oval film-coated tablets, approximate dimensions 6.74 mm x 12.2 mm and debossed with “MVC 75”.
Slovenian: Modra, bikonveksna, ovalna filmsko obložena tableta, velika približno 6,74 mm x 12,2 mm, z vtisnjeno oznako "MVC 75".
English: Efavirenz concentrations not measured, no effect is expected.
Slovenian: Koncentracija efavirenza ni bila merjena, učinki niso pričakovani.
English: Maraviroc concentrations not measured, no interaction expected.
Slovenian: Koncentracija maraviroka ni bila merjena, medsebojno delovanje ni pričakovano.
English: Maraviroc AUC12: ↔ 1.03
Slovenian: Maravirok AUC12: ↔ 1,03
English: Blue, biconvex, oval film-coated tablets, approximate dimensions 10.5 mm x 19.0 mm and debossed with “MVC 300”.
Slovenian: Modra, bikonveksna, ovalna filmsko obložena tableta, velika približno 10,5 mm x 19,0 mm, z vtisnjeno oznako "MVC 300".
English: You need to know about important signs and symptoms to look out for while you're taking CELSENTRI.
Slovenian: Medtem ko jemljete zdravilo CELSENTRI, morate biti seznanjeni s pomembnimi znaki in simptomi.
English: Maraviroc AUC12 ↑ 4.88
Slovenian: Maravirok AUC12: ↑ 4,88
English: Maraviroc Cmax: ↑ 2.67
Slovenian: Maravirok Cmax: ↑ 2,67
English: Excipient with known effect: each 150 mg film-coated tablet contains 0.84 mg of soya lecithin.
Slovenian: Pomožne snovi z znanim učinkom: ena 150 mg filmsko obložena tableta vsebuje 0,84 mg sojinega lecitina.
English: • other medicines to treat HIV or hepatitis C infection (such as atazanavir, cobicistat, darunavir,
Slovenian: • druga zdravila za zdravljenje okužbe s HIV ali hepatitisom C (npr. atazanavir, kobicistat, darunavir, efavirenz, etravirin, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, sakvinavir, boceprevir, telaprevir),
English: Each film-coated tablet contains 25 mg of maraviroc.
Slovenian: Ena filmsko obložena tableta vsebuje 25 mg maraviroka.
English: Excipient with known effect: each 25 mg film-coated tablet contains 0.14 mg of soya lecithin.
Slovenian: Pomožne snovi z znanim učinkom: ena 25 mg filmsko obložena tableta vsebuje 0,14 mg sojinega lecitina.
English: Protease Inhibitors (PIs) Atazanavir 400 mg QD (maraviroc 300 mg BID)
Slovenian: Zaviralci proteaz (PI) Atazanavir 400 mg enkrat na dan (maravirok 300 mg dvakrat na dan)
English: Pharmacokinetic Enhancers Cobicistat
Slovenian: PROTIMIKROBNE UČINKOVINE Protiretrovirusna zdravila Farmakokinetični spodbujevalci Kobicistat
English: Atazanavir/ritonavir 300 mg/100 mg QD (maraviroc 300 mg BID)
Slovenian: Atazanavir/ritonavir 300 mg/100 mg enkrat na dan (maravirok 300 mg dvakrat na dan)
English: Ritonavir AUC12: ↓ 0.66 Ritonavir Cmax: ↓ 0.61
Slovenian: Ritonavir AUC12: ↓ 0,66 Ritonavir Cmax: ↓ 0,61 Ritonavir C12: ↔ 0,86
English: Maraviroc AUC12 ↑ 9.77
Slovenian: Maravirok AUC12: ↑ 9,77
English: Signs include:
Slovenian: Pojavijo se naslednji znaki:
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING Bottle label - maraviroc 20 mg/ml oral solution
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA PRIMARNI OVOJNINI Nalepka na plastenki - 20 mg/ml peroralna raztopina
English: 120 film-coated tablets
Slovenian: 60 filmsko obloženih tablet
English: Co-administration of maraviroc with St. John's Wort is expected to substantially decrease maraviroc concentrations and may result in suboptimal levels and lead to loss of virologic response and possible resistance to maraviroc.
Slovenian: To lahko povzroči suboptimalno raven maraviroka, izgubo virološkega odziva in možen pojav odpornosti proti maraviroku.
English: Maraviroc Cmax: ↑ 2.26
Slovenian: Maravirok Cmax: ↑ 2,26
English: CELSENTRI 300 mg twice daily and sulphamethoxazole/ trimethoprim can be co-administered without dose adjustment.
Slovenian: Zdravilo CELSENTRI 300 mg dvakrat na dan je mogoče uporabljati sočasno s sulfametoksazolom/trimetoprimom brez prilagoditve odmerka.
English: Maraviroc Cmax: ↑ 2.29
Slovenian: Maravirok Cmax: ↑ 2,29
English: Maraviroc AUC12 ↑ 4.05
Slovenian: Maravirok AUC12: ↑ 4,05
English: ANTIFUNGALS Ketoconazole 400 mg QD (maraviroc 100 mg BID)
Slovenian: ANTIMIKOTIKI Ketokonazol 400 mg enkrat na dan (maravirok 100 mg dvakrat na dan)
English: Tenofovir 300 mg QD (maraviroc 300 mg BID)
Slovenian: Tenofovir 300 mg enkrat na dan (maravirok 300 mg dvakrat na dan)
English: Studies in Treatment-Experienced Adult Patients Infected with Non-CCR5-tropic Virus
Slovenian: Študije pri predhodno že zdravljenih odraslih bolnikih okuženih z ne-CCR5-tropnim virusom
English: Cellulose, microcrystalline Calcium hydrogen phosphate, anhydrous
Slovenian: Jedro tablete mikrokristalna celuloza brezvodni kalcijev hidrogenfosfat natrijev karboksimetilškrob magnezijev stearat
English: Citric acid (anhydrous) Sodium citrate dihydrate Sucralose
Slovenian: 6.1 Seznam pomožnih snovi citronska kislina (brezvodna) natrijev citrat dihidrat sukraloza natrijev benzoat jagodna aroma prečiščena voda
English: Darunavir/ritonavir 600 mg/100 mg BID (maraviroc 150 mg BID)
Slovenian: Darunavir/ritonavir 600 mg/100 mg dvakrat na dan (maravirok 150 mg dvakrat na dan)
English: Each film-coated tablet contains 150 mg of maraviroc.
Slovenian: Ena filmsko obložena tableta vsebuje 150 mg maraviroka.
English: Studies in Treatment-Experienced Paediatric Patients Infected with CCR5-tropic Virus
Slovenian: Študije pri predhodno že zdravljenih pediatričnih bolnikih okuženih z CCR5-tropnim virusom
English: Package leaflet: information for the user CELSENTRI 20 mg /ml oral solution maraviroc
Slovenian: IME ZDRAVILA CELSENTRI 20 mg/ml peroralna raztopina maravirok
English: except in combination with tipranavir/ritonavir where the CELSENTRI dose should be 300 mg BID.
Slovenian: dan; izjema je uporaba v kombinaciji s tipranavirjem/ritonavirjem: v tem primeru mora biti odmerek zdravila CELSENTRI 300 mg dvakrat na dan.
English: CELSENTRI 300 mg twice daily and digoxin can be co-administered without dose adjustment.
Slovenian: Zdravilo CELSENTRI 300 mg dvakrat na dan in digoksin je mogoče uporabljati sočasno brez prilagoditve odmerka.
English: HIV-1 variants with reduced susceptibility to maraviroc have been selected in vitro, following serial passage of two CCR5-tropic viruses (0 laboratory strains, 2 clinical isolates).
Slovenian: In vitro so z zaporedno pasažo dveh CCR5-tropnih virusov (0 laboratorijskih sevov, 2 klinična izolata) selekcionirali variante HIV-1 z manjšo občutljivostjo za maravirok.
English: Blue, biconvex, oval film-coated tablets, approximate dimensions 4.6 mm x 8.0 mm and debossed with “MVC 25”.
Slovenian: Modra, bikonveksna, ovalna filmsko obložena tableta, velika približno 4,6 mm x 8,0 mm, z vtisnjeno oznako "MVC 25".
English: Bottle label - 75 mg film-coated tablets
Slovenian: PODATKI NA ZUNANJI OVOJNINI Škatla za plastenko - 75 mg filmsko obložene tablete
English: Saquinavir/ritonavir 1000 mg/100 mg BID (maraviroc 100 mg BID)
Slovenian: Sakvinavir/ritonavir 1000 mg/100 mg dvakrat na dan (maravirok 100 mg dvakrat na dan)
English: How to store CELSENTRI
Slovenian: Shranjevanje zdravila CELSENTRI
English: Maraviroc concentrations not measured, no effect is expected.
Slovenian: Koncentracija maraviroka ni bila merjena, učinki niso pričakovani.
English: celsentri 75 mg
Slovenian: PODATKI V BRAILLOVI PISAVI celsentri 75 mg
English: Elvitegravir/ritonavir 150/100mg QD (maraviroc 150 mg BID)
Slovenian: Elvitegravir/ritonavir 150/100 mg enkrat na dan (maravirok 150 mg dvakrat na dan)
English: Blister Strip of 10 tablets of 300 mg maraviroc film-coated tablets
Slovenian: Pretisni omot za 10 tablet 300 mg filmsko obloženih tablet maraviroka
English: CELSENTRI 75 mg film-coated tablets maraviroc
Slovenian: IME ZDRAVILA CELSENTRI 75 mg filmsko obložene tablete maravirok
English: Bottle label - 25 mg film-coated tablets
Slovenian: PODATKI NA ZUNANJI OVOJNINI Škatla za plastenko - 25 mg filmsko obložene tablete
English: Rifampicin 600 mg QD (maraviroc 100 mg BID)
Slovenian: Rifampicin 600 mg enkrat na dan (maravirok 100 mg dvakrat na dan)
English: Maraviroc AUC12 ↔ 1.02
Slovenian: Maravirok AUC12: ↔ 1,02
English: Maraviroc Cmax: ↓ 0.49
Slovenian: Maravirok Cmax: ↓ 0,49
English: Fosamprenavir/ritonavir 700 mg/100 mg BID (maraviroc 300 mg BID)
Slovenian: Fosamprenavir/ritonavir 700 mg/100 mg dvakrat na dan (maravirok 300 mg dvakrat na dan)
English: Bottle label - 300 mg film-coated tablets
Slovenian: PODATKI NA ZUNANJI OVOJNINI Škatla za plastenko - 300 mg filmsko obložene tablete
English: Maraviroc Cmax: ↔ 0.86
Slovenian: Maravirok Cmax: ↔ 0,86
English: Blister Strip of 10 tablets of 150 mg maraviroc film-coated tablets
Slovenian: Pretisni omot za 10 tablet 150 mg filmsko obloženih tablet maraviroka
English: Etravirine 200 mg BID (maraviroc 300 mg BID)
Slovenian: Etravirin 200 mg dvakrat na dan (maravirok 300 mg dvakrat na dan)
English: AUC: ↔ 1.18 Midazolam.
Slovenian: AUC: ↔ 1,18
English: Maraviroc Cmax: ↓ 0.34
Slovenian: Maravirok Cmax: ↓ 0,34
English: celsentri 25 mg
Slovenian: PODATKI V BRAILLOVI PISAVI celsentri 25 mg
English: Bottle label - 150 mg film-coated tablets
Slovenian: PODATKI NA ZUNANJI OVOJNINI Škatla za plastenko - 150 mg filmsko obložene tablete
English: HIV-1 clinical isolates resistant to NRTIs, NNRTIs, PIs and enfuvirtide were all susceptible to maraviroc in cell culture.
Slovenian: V celični kulturi so bili za maravirok občutljivi klinični izolati HIV-1, odporni proti nukleozidnim zaviralcem reverzne transkriptaze, nenukleozidnim zaviralcem reverzne transkriptaze, zaviralcem proteaz in enfuvirtidu.
English: Lopinavir/ritonavir 400 mg/100 mg BID (maraviroc 300 mg BID)
Slovenian: Lopinavir/ritonavir 400 mg/100 mg dvakrat na dan (maravirok 300 mg dvakrat na dan)
English: Levonorgestrel 150 mcg QD (maraviroc 100 mg BID)
Slovenian: Levonorgestrel 150 mikrogramov enkrat na dan (maravirok 100 mg dvakrat na dan)
English: PHARMACEUTICAL FORM AND CONTENTS
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Vsebina plastenke:
English: celsentri 150 mg
Slovenian: PODATKI V BRAILLOVI PISAVI celsentri 150 mg
English: CELSENTRI dose should be decreased to 150 mg twice daily when co-administered with rifabutin and a PI (except tipranavir/ritonavir where the dose should be 300 mg twice daily).
Slovenian: Če je zdravilo CELSENTRI uporabljeno sočasno z zaviralcem proteaz, je treba njegov odmerek zmanjšati na 150 mg dvakrat na dan; izjema je uporaba v kombinaciji s tipranavirjem/ritonavirjem: v tem primeru mora biti odmerek zdravila CELSENTRI 300 mg dvakrat na dan.
English: Pegylated interferon has not been studied, no interaction is expected.
Slovenian: Pegilirani interferon Pegilirani interferon ni raziskan;
English: The hepatic safety of maraviroc in combination with other antiretroviral agents in CCR5-tropic HIV-1-infected subjects with HIV RNA <50 copies/mL, co-infected with Hepatitis C and/or Hepatitis B Virus was evaluated in a multicentre, randomized, double blinded, placebo-controlled study.
Slovenian: Z multicentrično, randomizirano, dvojno slepo, s placebom kontrolirano študijo je bila ocenjena jetrna varnost maraviroka v kombinaciji z drugimi protiretrovirusnimi zdravili pri preiskovancih, okuženih z CCR5-tropnim virusom HIV-1 in HIV RNA < 50 kopij/ml, sočasno okuženih z virusom hepatitisa C in/ali hepatitisa B. 70 preiskovancev (Child-Pugh A, N = 64; Child-Pugh B, N = 6) so randomizirali v skupino z maravirokom, 67 preiskovancev (Child-Pugh A, N = 59; Child-Pugh B, N = 8) pa v skupino s placebom.
English: Musculoskeletal and connective tissue disorders
Slovenian: Bolezni živčevja konvulzije in konvulzivne motnje občasni