FrancophonIA/ELRC3.0 huggingface dataset:
English: Similar to the first study the incidence of VTE during extended prophylaxis was significantly lower for enoxaparin sodium compared to placebo for both total VTE (enoxaparin sodium 21 [16%] versus placebo 45 [34.4%]; p=0.001) and proximal DVT (enoxaparin sodium 8 [6.1%] versus placebo 28 [21.4%]; p=<0.001).
Croatian: Slično kao i u prvom ispitivanju, incidencija VTE-a tijekom produljene profilakse bila je značajno niža uz enoksaparinnatrij nego uz placebo i za ukupni VTE (21 uz enoksaparinnatrij [16%] naspram 45 uz placebo [34,4%]; p=0,001) i za proksimalni DVT (8 uz enoksaparinnatrij [6,1%] naspram 28 uz placebo [21,4%]; p < 0,001).
English: The drug substance is the sodium salt.
Croatian: Djelatna tvar je natrijeva sol.
English: • Rare: Spinal haematoma* (or neuraxial haematoma).
Croatian: • Rijetko: hematom kralježnice* (ili neuraksijalni hematom).
English: What Thorinane contains - The active substance is enoxaparin sodium.
Croatian: Što Thorinane sadrži - Djelatna tvar je enoksaparinnatrij.
English: In patients with renal impairment, there is an increase in exposure of enoxaparin sodium which increases the risk of bleeding.
Croatian: U bolesnika s oštećenjem bubrežne funkcije povećana je izloženost enoksaparinnatriju, što povećava rizik od krvarenja.
English: Enoxaparin sodium was found to have no effect on fertility or reproductive performance of male and female rats at SC doses up to 20 mg/kg/day.
Croatian: Utvrđeno je da enoksaparinnatrij ne utječe na plodnost ni reproduktivnu sposobnost mužjaka i ženki štakora pri supkutanim dozama do 20 mg/kg/dan.
English: What you need to know before you use Thorinane
Croatian: Što morate znati prije nego počnete primjenjivati Inhixu
English: Based on literature data the use of enoxaparin sodium 4,000 IU (40 mg) in cirrhotic patients (Child-Pugh class B-C) appears to be safe and effective in preventing portal vein thrombosis.
Croatian: Prema podacima iz literature, čini se da je primjena enoksaparinnatrija u dozi od 4000 IU (40 mg) u bolesnika s cirozom (Child-Pugh stadij B-C) sigurna i učinkovita za sprječavanje tromboze portalne vene.
English: Hard mass or lump at the injection site
Croatian: • tvrda masa ili kvržica na mjestu injiciranja
English: It is advised that the trade name and batch number of the product you are using are recorded by your healthcare professional.
Croatian: Preporučuje se da zdravstveni radnik zabilježi naziv i broj serije lijeka koji primjenjujete u Vaš zdravstveni karton.
English: In a clinical study of pregnant women with mechanical prosthetic heart valves given enoxaparin sodium (100 IU/kg (1 mg/kg ) twice daily) to reduce the risk of thromboembolism, 2 of 8 women developed clots resulting in blockage of the valve and leading to maternal and foetal death.
Croatian: U kliničkom ispitivanju provedenom u trudnica s mehaničkim umjetnim srčanim zaliscima koje su primale enoksaparinnatrij (100 IU/kg [1 mg/kg] dvaput na dan) za smanjenje rizika od tromboembolije, u 2 od 8 žena nastali su krvni ugrušci koji su uzrokovali opstrukciju zaliska i tako doveli do smrti majke i ploda.
English: During haemodialysis, enoxaparin sodium should be introduced into the arterial line of the circuit at the beginning of the dialysis session.
Croatian: Tijekom hemodijalize, enoksaparinnatrij treba injicirati kroz arterijsku liniju sustava za dijalizu na početku postupka dijalize.
English: • Pregnant women with mechanical prosthetic heart valves
Croatian: • Trudnice s mehaničkim umjetnim srčanim zaliscima
English: You will be given 2,000 IU (20 mg) or 4,000 IU (40 mg) of Thorinane each day.
Croatian: Svaki ćete dan primati 2000 IU (20 mg) ili 4000 IU (40 mg) lijeka Thorinane.
English: No difference in major bleeding was found between the enoxaparin sodium and the placebo group.
Croatian: Nije utvrđena razlika u velikim krvarenjima između skupine liječene enoksaparinnatrijem i one koja je primala placebo.
English: Your doctor may request you perform a blood test to check your platelet count.
Croatian: Vaš će liječnik možda zatražiti da napravite krvne pretrage da bi provjerio broj trombocita.
English: • Stop blood clots from forming in your blood in the following situations: o When you have an acute illness and face period of limited mobility o When you have unstable angina (a condition when not enough blood gets to your heart)
Croatian: • sprječavanje nastanka ugrušaka u krvi u sljedećim situacijama: o prije i nakon operacije o kada imate akutnu bolest i možda ćete neko vrijeme biti manje pokretni o kada imate nestabilnu anginu pektoris (stanje kod kojega do srca ne dospijeva dovoljna količina krvi) o nakon srčanog udara
English: All patients also received warfarin sodium (dose adjusted according to prothrombin time to achieve an INR of 2.0 to 3.0), commencing within 72 hours of initiation of enoxaparin sodium or standard heparin therapy, and continuing for 90 days.
Croatian: Svi su bolesnici primali i varfarinnatrij (doza se prilagođavala prema protrombinskom vremenu radi postizanja INR-a od 2,0 do 3,0), počevši 72 sata nakon početka liječenja enoksaparinnatrijem ili standardnim heparinom pa tijekom razdoblja od 90 dana.
English: To minimize the risk of bleeding following the vascular instrumentation during the treatment of unstable angina, NSTEMI and acute STEMI, adhere precisely to the intervals recommended between enoxaparin sodium injection doses.
Croatian: Kako bi se minimizirao rizik od krvarenja nakon krvožilnog pristupa tijekom liječenja nestabilne angine, NSTEMI-ja i akutnog STEMI-ja, treba se točno pridržavati preporučenih intervala između injekcijskih doza enoksaparinnatrija.
English: • Other medicinal products affecting haemostasis such as: - Platelet aggregation inhibitors including acetylsalicylic acid used at antiaggregant dose (cardioprotection), clopidogrel, ticlopidine, and glycoprotein IIb/IIIa antagonists indicated in acute coronary syndrome due to the risk of bleeding, - Dextran 40, - Systemic glucocorticoids.
Croatian: • Ostali lijekovi koji utječu na hemostazu, kao što su: - inhibitori agregacije trombocita, uključujući acetilsalicilatnu kiselinu u antiagregacijskoj dozi (kardioprotekcija), klopidogrel, tiklopidin i antagoniste glikoproteina IIb/IIIa indicirane kod akutnog koronarnog sindroma zbog rizika od krvarenja - dekstran 40 - sistemski glukokortikoidi
English: After you have had a heart attack
Croatian: Nakon srčanog udara
English: Enoxaparin sodium is to be used with extreme caution in patients with a history (>100 days) of heparininduced thrombocytopenia without circulating antibodies.
Croatian: Enoksaparinnatrij se mora primjenjivati uz osobit oprez u bolesnika koji u anamnezi (> 100 dana) imaju heparinom izazvanu trombocitopeniju bez cirkulirajućih protutijela.
English: The signs may include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue.
Croatian: Znakovi mogu uključivati: osip, otežano gutanje ili disanje, oticanje usana, lica, grla ili jezika.
English: There was a higher incidence of gastrointestinal bleeding in the enoxaparin sodium group (0.5%) versus the heparin group (0.1%), while the incidence of intracranial haemorrhage was similar in both groups (0.8% with enoxaparin sodium versus 0.7% with heparin).
Croatian: Incidencija gastrointestinalnog krvarenja bila je viša u skupini liječenoj enoksaparinnatrijem (0,5%) nego u onoj koja je primala heparin (0,1%), dok je incidencija intrakranijalnog krvarenja bila slična u obje skupine (0,8% uz enoksaparinnatrij naspram 0,7% uz heparin).
English: • Active clinically significant bleeding and conditions with a high risk of haemorrhage, including recent haemorrhagic stroke, gastrointestinal ulcer, presence of malignant neoplasm at high risk of bleeding, recent brain, spinal or ophthalmic surgery, known or suspected oesophageal varices, arteriovenous malformations, vascular aneurysms or major intraspinal or intracerebral vascular abnormalities;
Croatian: • aktivnim klinički značajnim krvarenjem i stanjima kod kojih postoji visok rizik od krvarenja, uključujući nedavno pretrpljen hemoragijski moždani udar, gastrointestinalni ulkus, prisutnost zloćudne novotvorine kod koje postoji visok rizik od krvarenja, nedavno proveden kirurški zahvat na mozgu, kralježnici ili očima, poznate ili suspektne varikozitete jednjaka, arteriovenske malformacije, krvožilne aneurizme ili značajne intraspinalne ili intracerebralne krvožilne abnormalnosti
English: • Spinal or epidural anaesthesia or loco-regional anaesthesia when enoxaparin sodium is used for treatment in the previous 24 hours (see section 4.4).
Croatian: • spinalnom ili epiduralnom anestezijom ili lokoregionalnom anestezijom kada je enoksaparinnatrij primijenjen za liječenje unutar prethodna 24 sata (vidjeti dio 4.4)
English: 2,000 IU (20 mg) SC once daily
Croatian: 2000 IU (20 mg) s.c. jedanput na dan
English: - Treatment of acute ST-segment elevation myocardial infarction (STEMI) including patients to be managed medically or with subsequent percutaneous coronary intervention (PCI).
Croatian: ST-segment elevation myocardial infarction, STEMI), uključujući bolesnike koji će se liječiti medikamentozno ili koji će naknadno biti podvrgnuti perkutanoj koronarnoj intervenciji (engl. percutaneous coronary intervention, PCI)
English: • you have diabetes or problems with blood vessels in the eye caused by diabetes (called diabetic
Croatian: • ako imate šećernu bolest ili tegobe s krvnim žilama u oku uzrokovane šećernom bolešću (što se naziva dijabetičkom retinopatijom)
English: You may have a blood test before you start using this medicine and at intervals while you are using it; this is to check the level of the clotting cells (platelets) and potassium in your blood.
Croatian: Prije nego što počnete uzimati ovaj lijek i povremeno tijekom njegove primjene možda ćete obavljati krvne pretrage; njima se želi provjeriti broj stanica koje zgrušavaju krv (trombocita) i razina kalija u krvi.
English: Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency.
Croatian: Enoksaparinnatrij se prvenstveno metabolizira u jetri procesima desulfatacije i/ili depolimerizacije, kojima se razgrađuje na elemente manje molekulske mase i uvelike smanjene biološke aktivnosti.
English: If an epidural anaesthesia is planned, it is recommended to withdraw enoxaparin sodium treatment before (see section 4.4).
Croatian: Ako se planira epiduralna anestezija, preporučuje se prije toga prekinuti primjenu enoksaparinnatrija (vidjeti dio 4.4).
English: These included 1,776 for prophylaxis of deep vein thrombosis following orthopaedic or abdominal surgery in patients at risk for thromboembolic complications, 1,169 for prophylaxis of deep vein thrombosis in acutely ill medical patients with severely restricted mobility, 559 for treatment of DVT with or without PE, 1,578 for treatment of unstable angina and non-Q-wave myocardial infarction and 10,176 for treatment of acute STEMI.
Croatian: To je uključivalo 1776 slučajeva profilakse duboke venske tromboze nakon ortopedskog ili abdominalnog kirurškog zahvata u bolesnika s rizikom od tromboembolijskih komplikacija, 1169 slučajeva profilakse duboke venske tromboze u medikamentozno liječenih bolesnika s akutnom bolešću i izuzetno ograničenom pokretljivošću, 559 slučajeva liječenja DVT-a praćenog PE-om ili bez njega, 1578 slučajeva liječenja nestabilne angine i infarkta miokarda bez Q-zupca te 10 176 slučajeva liječenja akutnog STEMI-ja.
English: Signs of an allergic reaction include: rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue.
Croatian: Znakovi alergijske reakcije uključuju: osip, otežano gutanje ili disanje, oticanje usana, lica, grla ili jezika.
English: • Rare: Eosinophilia*
Croatian: • Rijetko: eozinofilija*
English: • Prophylaxis of venous thromboembolic disease in moderate and high risk surgical patients, in particular those undergoing orthopaedic or general surgery including cancer surgery.
Croatian: • profilaksu venske tromboembolijske bolesti u umjereno rizičnih i visokorizičnih kirurških bolesnika, osobito onih koji se podvrgavaju ortopedskim ili općim kirurškim zahvatima, uključujući onkološke kirurške zahvate
English: - The pre-filled syringe is intended for single use only.
Croatian: - Napunjena štrcaljka namijenjena je samo za jednokratnu uporabu.
English: Acute coronary syndrome: treatment of unstable angina and NSTEMI and treatment of acute STEMI
Croatian: Akutni koronarni sindrom: liječenje nestabilne angine i NSTEMI-ja te liječenje akutnog STEMI-ja
English: In moderate risk patients, enoxaparin sodium treatment should be maintained for a minimal period of 710 days whatever the recovery status (e.g. mobility).
Croatian: U umjereno rizičnih bolesnika liječenje enoksaparinnatrijem treba održavati tijekom najmanje 7 - 10 dana, neovisno o statusu oporavka (npr. pokretljivosti).
English: In case a closure device is used, the sheath can be removed immediately.
Croatian: Ako se koristi pomagalo za okluziju, uvodnica se može odmah ukloniti.
English: The incidence of DVT during extended prophylaxis was significantly lower for enoxaparin sodium compared to placebo, no PE was reported.
Croatian: Incidencija DVT-a tijekom produljene profilakse bila je značajno niža uz enoksaparinnatrij nego uz placebo, a nije prijavljen nijedan slučaj PE-a.
English: The rates of venous thromboembolism at the end of the double-blind phase were 12.0 % (n=20) in the placebo group and 4.8% (n=8) in the enoxaparin sodium group; p=0.02.
Croatian: Stopa venske tromboembolije na kraju dvostruko slijepe faze iznosila je 12,0% (n=20) u skupini koja je primala placebo te 4,8% (n=8) u skupini liječenoj enoksaparinnatrijem; p=0,02.
English: Indication Prophylaxis of venous thromboembolic disease
Croatian: Profilaksa venske tromboembolijske bolesti
English: Prevention of venous thromboembolic disease associated with surgery
Croatian: Profilaksa venske tromboembolijske bolesti povezane s kirurškim zahvatom
English: The risk of these events is higher with the use of post-operative indwelling epidural catheters, with the concomitant use of additional drugs affecting haemostasis such as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), with traumatic or repeated epidural or spinal puncture, or in patients with a history of spinal surgery or spinal deformity.
Croatian: Rizik od tih događaja veći je kod uporabe poslijeoperacijskih trajnih epiduralnih katetera, istodobne primjene dodatnih lijekova koji utječu na hemostazu, poput nesteroidnih protuupalnih lijekova (NSAIL), traumatske ili ponovljene epiduralne ili spinalne punkcije, kao i u bolesnika koji u anamnezi imaju kirurški zahvat na kralježnici ili deformaciju kralježnice.
English: For patients with a high risk of haemorrhage, the dose should be reduced to 50 IU/kg (0.5 mg/kg) for double vascular access or 75 IU/kg (0.75 mg/kg) for single vascular access.
Croatian: U bolesnika s visokim rizikom od krvarenja, dozu treba smanjiti na 50 IU/kg (0,5 mg/kg) kod dvostrukog žilnog pristupa ili 75 IU/kg (0,75 mg/kg) kod jednostrukog žilnog pristupa.
English: These events are rare with enoxaparin sodium dosage regimens 4,000 IU (40 mg) once daily or lower.
Croatian: Ti su događaji rijetki kada se enoksaparinnatrij primjenjuje u dozama od 4000 IU (40 mg) jedanput na dan ili nižima.
English: Enoxaparin sodium has shown no mutagenic activity based on in vitro tests, including the Ames test, mouse lymphoma cell forward mutation test, and no clastogenic activity based on an in vitro human lymphocyte chromosomal aberration test, and the in vivo rat bone marrow chromosomal aberration test.
Croatian: Enoksaparinnatrij nije pokazao mutageno djelovanje u testovima in vitro, uključujući Amesov test i test mutacija na mišjim stanicama limfoma, kao ni klastogeno djelovanje u testu kromosomskih aberacija na ljudskim limfocitima in vitro i testu kromosomskih aberacija na stanicama koštane srži štakora in vivo.
English: Enoxaparin sodium pharmacokinetics appears to be linear over the recommended dosage ranges.
Croatian: Čini se da je farmakokinetika enoksaparinnatrija linearna u svim preporučenim rasponima doza.
English: - Changing from treatment with direct oral anticoagulant to Thorinane Stop taking direct oral anticoagulant.
Croatian: - Prelazak s liječenja direktnim oralnim antikoagulansima na Thorinane Prestanite uzimati direktni oralni antikoagulans.
English: Besides the anticoagulant effects of enoxaparin sodium, there was no evidence of adverse effects at 15 mg/kg/day in the 13-week SC toxicity studies both in rats and dogs and at 10 mg/kg/day in the 26-week SC and IV toxicity studies both in rats, and monkeys.
Croatian: Osim antikoagulacijskih učinaka enoksaparinnatrija, nije bilo dokaza štetnih učinaka pri dozi od 15 mg/kg na dan u 13-tjednom ispitivanju toksičnosti supkutane primjene ni u štakora ni u pasa, te pri dozi od 10 mg/kg na dan u 26-tjednom ispitivanju toksičnosti supkutane i intravenske primjene ni u štakora ni u majmuna.
English: The dose regimen of 100 IU/kg (1 mg/kg) administered twice daily should be used in all other patients such as those with obesity, with symptomatic PE, cancer, recurrent VTE or proximal (vena iliaca) thrombosis.
Croatian: Režim doziranja od 100 IU/kg (1 mg/kg) dvaput na dan treba koristiti u svih ostalih bolesnika, kao što su pretili bolesnici, bolesnici sa simptomatskim PE-om, rakom, rekurentnim VTE-om ili proksimalnom trombozom (trombozom ilijačne vene).
English: Spinal/epidural anaesthesia or lumbar puncture must not be performed within 24 hours of administration of enoxaparin sodium at therapeutic doses (see also section 4.3).
Croatian: Spinalna/epiduralna anestezija ili lumbalna punkcija ne smiju se izvoditi unutar 24 sata od primjene enoksaparinnatrija u terapijskim dozama (vidjeti i dio 4.3).
English: For the prophylaxis of venous thrombo-embolic disease following surgery, treatment of DVT and PE, treatment of unstable angina and NSTEMI, enoxaparin sodium should be administered by SC injection.
Croatian: Za profilaksu venske tromboembolijske bolesti nakon kirurškog zahvata, liječenje DVT-a i PE-a te liječenje nestabilne angine i NSTEMI-ja, enoksaparinnatrij treba primjenjivati supkutanom injekcijom.
English: 4) Carefully pull off the needle cap from the syringe.
Croatian: 4) Oprezno povlačenjem skinite pokrov igle sa štrcaljke.
English: The following medicinal products may be administered with caution concomitantly with enoxaparin sodium:
Croatian: Istodobna primjena uz oprez: Sljedeći se lijekovi mogu primjenjivati zajedno s enoksaparinnatrijem uz oprez:
English: Patients received enoxaparin sodium (4,000 IU (40 mg) SC) daily for 6 to 10 days and were then randomly assigned to receive either enoxaparin sodium or placebo for another 21 days.
Croatian: Bolesnici su primali enkosaparinnatrij (4000 IU [40 mg] s.c.) svakodnevno tijekom 6 do 10 dana, nakon čega su bili randomizirani za primanje enoksaparinnatrija ili placeba tijekom još 21 dana.
English: The incidence of major bleeding at 30 days was significantly higher (p<0.0001) in the enoxaparin sodium group (2.1%) versus the heparin group (1.4%).
Croatian: Incidencija velikih krvarenja nakon 30 dana bila je značajno viša (p < 0,0001) u skupini liječenoj enoksaparinnatrijem (2,1%) nego u onoj koja je primala heparin (1,4%).
English: The risk of HIT is higher in postoperative patients and mainly after cardiac surgery and in patients with cancer.
Croatian: Rizik od HIT-a veći je u poslijeoperacijskih bolesnika, i to prvenstveno nakon kirurških zahvata na srcu, te u onkoloških bolesnika.
English: Obese patients are at higher risk for thromboembolism.
Croatian: Pretili bolesnici imaju veći rizik od tromboembolije.
English: For continuous techniques, a similar delay of at least 12 hours should be observed before removing the catheter.
Croatian: Kada se koriste kontinuirane tehnike, prije uklanjanja katetera također mora proći najmanje 12 sati.
English: • Thorinane can be added to the tube leaving the body (arterial line) at the start of the dialysis session.
Croatian: • Thorinane se može dodati u cijev koja izlazi iz tijela (arterijsku liniju) na početku dijalize.
English: There was a significant treatment benefit of enoxaparin sodium, as compared with unfractionated heparin, in patients who underwent percutaneous coronary intervention within 30 days after randomization (23 percent reduction in relative risk) or who were treated medically (15 percent reduction in relative risk, p=0.27 for interaction).
Croatian: Primijećena je značajna terapijska korist enoksaparinnatrija u usporedbi s nefrakcioniranim heparinom u bolesnika podvrgnutih perkutanoj koronarnoj intervenciji unutar 30 dana nakon randomizacije (smanjenje relativnog rizika za 23%) ili medikamentoznom liječenju (smanjenje relativnog rizika za 15%; p=0,27 za interakciju).
English: If a manual compression method is used, sheath should be removed 6 hours after the last IV/SC enoxaparin sodium injection.
Croatian: Ako se provodi ručna kompresija, uvodnicu treba ukloniti 6 sati nakon posljednje i.v./s.c. injekcije enoksparinnatrija.
English: Acetylsalicylic acid is recommended for all patients without contraindications at an initial oral loading dose of 150-300 mg (in acetylsalicylic acid-naive patients) and a maintenance dose of 75-325 mg/day long-term regardless of treatment strategy.
Croatian: Primjena acetilsalicilatne kiseline preporučuje se za sve bolesnike koji nemaju kontraindikacija, uz početnu peroralnu udarnu dozu od 150 do 300 mg (u bolesnika koji prethodno nisu bili liječeni acetilsalicilatnom kiselinom) i dugoročnu terapiju održavanja dozom od 75 do 325 mg/dan, neovisno o strategiji liječenja.
English: Insert the full length of the needle into the skin fold.
Croatian: Ubodite iglu cijelom dužinom u kožni nabor.
English: At approximately 3 months following enrolment, the incidence of VTE remained significantly lower in the enoxaparin sodium 4,000 IU (40 mg) treatment group versus the placebo treatment group.
Croatian: Približno 3 mjeseca nakon uključivanja u ispitivanje, incidencija VTE-a i dalje je bila značajno niža u skupini liječenoj enoksaparinnatrijem u dozi od 4000 IU (40 mg) nego u onoj koja je primala placebo.
English: The enoxaparin sodium dose was 4,000 IU (40 mg) SC once daily for prophylaxis of deep vein thrombosis following surgery or in acutely ill medical patients with severely restricted mobility.
Croatian: Doza enoksaparinnatrija iznosila je 4000 IU (40 mg) s.c. jedanput na dan za profilaksu duboke venske tromboze nakon kirurškog zahvata ili u medikamentozno liječenih bolesnika s akutnom bolešću i izuzetno ograničenom pokretljivošću.
English: 1) Stopping existing blood clots from getting any bigger.
Croatian: 1) Sprječava daljnje povećavanje postojećih krvnih ugrušaka.
English: In clinical studies, haemorrhages, thrombocytopenia and thrombocytosis were the most commonly reported reactions (see section 4.4 and 'Description of selected adverse reactions' below).
Croatian: U kliničkim su ispitivanjima najčešće prijavljene nuspojave bile krvarenja, trombocitopenija i trombocitoza (vidjeti dio 4.4 i odlomak "Opis odabranih nuspojava" u nastavku).
English: Extracorporeal use (in the dialysis circuit).
Croatian: Izvantjelesna primjena (u sustavu za dijalizu).
English: Appropriate antiplatelet therapy such as oral acetylsalicylic acid (75 mg to 325 mg once daily) should be administered concomitantly unless contraindicated.
Croatian: Potrebno je istodobno primjenjivati i odgovarajuću antitrombocitnu terapiju, poput peroralne primjene acetilsalicilatne kiseline (75 do 325 mg jedanput na dan), ako nije kontraindicirana.
English: • If you have restricted mobility due to illness, you will normally be given 4,000 IU (40 mg) of Thorinane each day.
Croatian: • Ako Vam je pokretljivost smanjena zbog bolesti, obično ćete svakodnevno primati 4000 IU