FrancophonIA/ELRC3.0 huggingface dataset:
English: The most common serious side effects (seen in more than 1 person in 100) with Cabometyx in patients with renal cell carcinoma are high blood pressure, diarrhoea, nausea (feeling sick), loss of appetite, tiredness, dehydration, hyponatraemia and hypomagnesaemia (low blood levels of sodium and magnesium), palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome, which involves rash and numbness on the palms and soles) and embolism (clot in a blood vessel).
Croatian: Najčešće ozbiljne nuspojave lijeka Cabometyx (zabilježene u više od 1 na 100 osoba) u bolesnika oboljelih od karcinoma bubrežnih stanica su visoki krvni tlak, proljev, mučnina, gubitak apetita, umor, dehidracija, hiponatremija i hipomagnezemija (niske razine natrija i magnezija u krvi), palmarnoplantarna eritrodizestezija (sindrom koji izaziva osip i utrnulost šaka i stopala) i embolija (ugrušci u krvnim žilama).
English: The European Medicines Agency therefore decided that Cabometyx's benefits are greater than its risks and it can be authorised for use in the EU.
Croatian: Europska agencija za lijekove zaključila je da koristi od lijeka Cabometyx nadmašuju s njim povezane rizike te da lijek može biti odobren za primjenu u Europskoj uniji.
English: Side effects reported with Cabometyx are carefully evaluated and any necessary action taken to protect patients.
Croatian: Nuspojave prijavljene za lijek Cabometyx pažljivo se procjenjuju i poduzimaju se potrebne mjere za zaštitu bolesnika.
English: Cabometyx is a cancer medicine used to treat adults with:
Croatian: Cabometyx je lijek protiv raka koji se primjenjuje za liječenje odraslih osoba oboljelih od:
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Cabometyx have been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Cabometyx nalaze se u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: In previously untreated patients with moderate or high risk disease, Cabometyx also provided clinically relevant benefit, delaying the progression of the cancer and the need for other treatments.
Croatian: Prethodno neliječenim bolesnicima koji imaju bolest srednjeg ili visokog rizika liječenjem lijekom Cabometyx osigurala se i klinički relevantna korist tako što se njime odgodila progresija raka i potreba za drugim terapijama.
English: As for all medicines, data on the use of Cabometyx are continuously monitored.
Croatian: Kao i za sve lijekove, podatci o primjeni lijeka Cabometyx kontinuirano se prate.
English: In addition, results indicated that patients treated with Cabometyx lived overall longer than patients treated with everolimus (an average of 21.4 months compared with 16.5 months).
Croatian: Osim toga, rezultati su pokazali da su bolesnici liječeni lijekom Cabometyx ukupno živjeli dulje od bolesnika liječenih everolimusom (u prosjeku 21,4 mjeseca u odnosu na 16,5 mjeseci).
English: What is Cabometyx and what is it used for?
Croatian: Što je Cabometyx i za što se primjenjuje?
English: Treatment is continued for as long as the patient benefits from it or until side effects become unacceptable.
Croatian: Liječenje treba nastaviti sve dok bolesnik ima koristi od terapije ili dok ne razvije neprihvatljive nuspojave.
English: Cabometyx can only be obtained with a prescription and treatment should be started by a doctor who has experience of using cancer medicines.
Croatian: Cabometyx se izdaje samo na liječnički recept, a liječenje mora započeti liječnik s iskustvom u primjeni lijekova protiv raka.
English: An overview of Cabometyx and why it is authorised in the EU
Croatian: Pregled informacija o lijeku Cabometyx i zašto je odobren u EU-u
English: Why is Cabometyx authorised in the EU?
Croatian: Zašto je lijek Cabometyx odobren u EU-u?
English: A second main study showed that Cabometyx was effective in adults with previously untreated renal cell carcinoma that was locally advanced or had spread elsewhere in the body.
Croatian: U drugom glavnom ispitivanju utvrđeno je da je lijek Cabometyx učinkovit u odraslih osoba s karcinomom bubrežnih stanica koji prethodno nije liječen, a koji je lokalno uznapredovao ili se proširio na druge dijelove tijela.
English: It is used in patients who have been previously treated with a type of cancer medicine called ‘vascular endothelial growth factor (VEGF) inhibitor'.
Croatian: Primjenjuje se u bolesnika koji su prethodno liječeni vrstom lijeka protiv raka naziva „inhibitor vaskularnog endotelnog čimbenika rasta (VEGF)”.
English: For more information about using Cabometyx, see the package leaflet or contact your doctor or pharmacist.
Croatian: Više informacija o primjeni lijeka Cabometyx pročitajte u uputi o lijeku, odnosno obratite se liječniku ili ljekarniku.
English: The study involved 157 patients, and compared Cabometyx with another cancer medicine, sunitinib.
Croatian: Ispitivanjem je bilo obuhvaćeno 157 bolesnika, a lijek Cabometyx uspoređen je s drugim lijekom za liječenje raka, sunitinibom.
English: The side effects of Cabometyx are similar to other tyrosine kinase inhibitors, and they are considered manageable.
Croatian: Nuspojave lijeka Cabometyx slične su onima drugih inhibitora tirozin kinaze i smatra se da ih je moguće kontrolirati.
English: What are the risks associated with Cabometyx?
Croatian: Koji su rizici povezani s lijekom Cabometyx?
English: Results also indicated that Cabometyx helped patients to live longer.
Croatian: Rezultati također pokazuju da je lijek Cabometyx pomogao u produljenju života bolesnika.
English: It is also used in patients who have not had previous treatment and whose cancer is at moderate or high risk of rapidly getting worse.
Croatian: Također se primjenjuje u bolesnika koji prethodno nisu liječeni, a izloženi su srednjem do visokom riziku od naglog pogoršanja bolesti.
English: The most common serious side effects (seen in more than 1 person in 100) with Cabometyx in patients with hepatocellular carcinoma are hepatic encephalopathy (harmful effects on the brain caused by liver damage), palmar-plantar erythrodysaesthesia syndrome, weakness and diarrhoea.
Croatian: Najčešće ozbiljne nuspojave lijeka Cabometyx (zabilježene u više od 1 na 100 osoba) u bolesnika oboljelih od hepatocelularnog karcinoma su jetrena encefalopatija (štetni učinci na mozak prouzročeni oštećenjem funkcije jetre), sindrom palmarno-plantarne eritrodizestezije, slabost i proljev.
English: In the study, Cabometyx was compared with placebo (a dummy treatment).
Croatian: Tijekom ispitivanja lijek Cabometyx uspoređen je s placebom (prividnim liječenjem).
English: One main study involving 658 adults with advanced renal cell carcinoma that had got worse despite treatment with a VEGF inhibitor showed that Cabometyx is effective at prolonging the time patients lived without their disease getting worse (progression-free survival).
Croatian: Glavnim ispitivanjem u kojem je sudjelovalo 658 odraslih osoba s uznapredovalim karcinomom bubrežnih stanica koji se pogoršao unatoč liječenju inhibitorom VEGF-a utvrđeno je da Cabometyx učinkovito produljuje razdoblje tijekom kojega bolesnici žive bez pogoršanja bolesti (preživljenje bez progresije).
English: The active substance in Cabometyx, cabozantinib, is a ‘tyrosine kinase inhibitor'.
Croatian: Djelatna tvar u lijeku Cabometyx, kabozantinib, inhibitor je tirozinske kinaze.
English: How does Cabometyx work?
Croatian: Kako djeluje Cabometyx?
English: One main study involving 707 adults with hepatocellular carcinoma who had already been treated with sorafenib showed that Cabometyx was effective at prolonging how long patients lived (overall survival).
Croatian: Glavnim ispitivanjem u kojem je sudjelovalo 707 odraslih osoba s hepatocelularnim karcinomom koji su prethodno bili liječeni sorafenibom utvrđeno je da Cabometyx učinkovito produljuje razdoblje preživljenja bolesnika (ukupno preživljenje).
English: • hepatocellular carcinoma (a liver cancer).
Croatian: • hepatocelularnog karcinoma (raka jetre).
English: In the study, Cabometyx was compared with the cancer medicine everolimus.
Croatian: Tijekom ispitivanja lijek Cabometyx uspoređen je s everolimusom, drugim lijekom protiv raka.
English: Patients treated with Cabometyx lived for an average of 8.6 months without their disease getting worse compared with 5.3 months in those treated with sunitinib.
Croatian: Bolesnici liječeni lijekom Cabometyx živjeli su u prosjeku 8,6 mjeseci bez pogoršanja bolesti, u usporedbi s 5,3 mjeseca u bolesnika liječenih sunitinibom.
English: What benefits of Cabometyx have been shown in studies?
Croatian: Koje su koristi od lijeka Cabometyx utvrđene u ispitivanjima?
English: Patients treated with Cabometyx lived for an average of 7.4 months without their disease getting worse compared with 3.8 months in patients treated with everolimus.
Croatian: Bolesnici liječeni lijekom Cabometyx živjeli su u prosjeku 7,4 mjeseca bez pogoršanja bolesti, u usporedbi s 3,8 mjeseci u bolesnika liječenih everolimusom.
English: Patients treated with Cabometyx lived on average for 10.2 months, compared with 8.0 months in patients who received placebo.
Croatian: Bolesnici liječeni lijekom Cabometyx živjeli su u prosjeku 10,2 mjeseca, a oni koji su primili placebo 8,0 mjeseci.
English: For the full list of side effects and restrictions with Cabometyx, see the package leaflet.
Croatian: Potpuni popis nuspojava i ograničenja zabilježenih pri primjeni lijeka Cabometyx potražite u uputi o lijeku.
English: In hepatocellular carcinoma, Cabometyx was shown to prolong survival in patients who had been treated with sorafenib.
Croatian: Kad je riječ o hepatocelularnom karcinomu, utvrđeno je da lijek Cabometyx produljuje preživljenje u bolesnika koji su prethodno bili liječeni sorafenibom.
English: The dose may need to be reduced or treatment stopped temporarily if serious or unacceptable side effects occur.
Croatian: U slučaju pojave teških ili neprihvatljivih nuspojava potrebno je smanjiti dozu ili privremeno prekinuti liječenje.
English: In advanced renal cell carcinoma, Cabometyx was shown to prolong the time previously treated patients lived without their disease getting worse.
Croatian: Kad je riječ o uznapredovalom karcinomu bubrežnih stanica, utvrđeno je da lijek Cabometyx produljuje razdoblje tijekom kojega prethodno liječeni bolesnici žive bez pogoršanja bolesti.
English: • advanced renal cell carcinoma (a kidney cancer).
Croatian: • uznapredovalog karcinoma bubrežnih stanica (raka bubrega).
English: Cabometyx contains the active substance cabozantinib.
Croatian: Cabometyx sadržava djelatnu tvar kabozantinib.
English: It is used on its own in patients who have already been treated with the cancer medicine sorafenib.
Croatian: Primjenjuje se kao monoterapija u bolesnika koji su prethodno liječeni drugim lijekom protiv raka naziva sorafenib.
English: How is Cabometyx used?
Croatian: Kako se Cabometyx primjenjuje?
English: Tablet
Croatian: Jačina
English: EMA Number
Croatian: EMA broj postupka (Novoizumljen o) ime
English: You should specifically tell your doctor if you take:
Croatian: Trebate posebno naglasiti svom liječniku ako uzimate:
English: What you need to know before you take [X] Other medicines and [X]
Croatian: Što morate znati prije nego počnete uzimati [X] Drugi lijekovi i [X]
English: - anti-retroviral medicines (medicines to treat HIV infections).
Croatian: -antiretrovirusne lijekove (lijekovi za liječenje infekcije HIV-om).
English: Not known: partial loss of vision
Croatian: Nepoznato: djelomičan gubitak vida
English: Not known: maculopathy
Croatian: Nepoznato: makulopatija
English: Adopted at the 13-16 May 2019 PRAC
Croatian: Usvojeno na sjednici PRAC-a održanoj 13. - 16. svibnja 2019.
English: There have been reports of long-lasting sexual dysfunction where the symptoms have continued despite discontinuation of SSRIs/SNRI.
Croatian: Postoje izvješća o dugotrajnom poremećaju seksualne funkcije gdje su se simptomi nastavili unatoč prestanku liječenja SSRI-ovima/SNRI-om.
English: 2 Desvenlafaxine; duloxetine; milnacipran; venlafaxine
Croatian: 2Desvenlafaksin; duloksetin; milnacipran; venlafaksin
English: Rare: spots in front of eyes, glaucoma, double vision, light hurts eye, blood in the eye, unequal sized pupils, vision abnormal, tear problem
Croatian: Rijetko: mrlje ispred očiju, glaukom, dvoslika, osjetljivost na svjetlo, krv u oku, zjenice nejednake veličine, abnormalan vid, problem sa suzama
English: Sertraline - Maculopathy (EPITT no 19341)
Croatian: Sertralin - Makulopatija (EPITT br. 19341)
English: 3 Citalopram; escitalopram; fluoxetine; fluvoxamine; paroxetine; sertraline 4 Clomipramine and vortioxetine were part of the signal assessment but are not concerned by the recommendation to update the product information.
Croatian: 3Citalopram; escitalopram; fluoksetin; fluvoksamin; paroksetin; sertralin 4 Klomipramin i vortioksetin bili su dio signalne procjene, ali nisu obuhvaćeni preporukom za ažuriranje informacija o lijeku.
English: Pantoprazole - Colitis microscopic (EPITT no 19342)
Croatian: Pantoprazol - mikroskopski kolitis (EPITT br. 19342)
English: Inflammation in the large bowel, that causes persistent watery diarrhoea
Croatian: Upala debelog crijeva koja uzrokuje ustrajan vodenasti proljev
English: Interaction with other medicinal products and other forms of interaction A significantly lower exposure to clopidogrel active metabolite and reduced platelet inhibition have been demonstrated in HIV-infected patients treated with ritonavir- or cobicistat-boosted anti-retroviral therapies (ART).
Croatian: 4.5. Interakcije s drugim lijekovima i drugi oblici interakcija Značajno niža izloženost aktivnom metabolitu klopidogrela i smanjena inhibicija trombocita opaženi su u bolesnika zaraženih HIV-om koji su liječeni antiretrovirusnim terapijama (ART) pojačanim ritonavirom ili kobicistatom.
English: Clopidogrel; clopidogrel, acetylsalicylic acid - Interaction with boosted antiviral human immunodeficiency virus (HIV) therapy leading to insufficient inhibition of platelet aggregation (EPITT no 19325)
Croatian: Klopidogrel; klopidogrel, acetilsalicilatna kiselinaInterakcija s pojačanom antivirusnom terapijom protiv virusa humane imunodeficijencije (HIV) koja dovodi do nedovoljne inhibicije agregacije trombocita (EPITT br. 19325)
English: Medicines like [Invented name] (so called SSRIs/SNRIs) may cause symptoms of sexual dysfunction (see section 4).
Croatian: [Novoizumljeno ime] (takozvani SSRI-ovi/SNRI-ovi) mogu uzrokovati simptome poremećaja seksualne funkcije (vidjeti dio 4).
English: Undesirable effects Tabulated list of adverse reactions Gastrointestinal disorders Frequency not known: Microscopic colitis
Croatian: Tablični popis nuspojava Poremećaji probavnog sustava Učestalost nepoznata: Mikroskopski kolitis
English: Serotonin and noradrenaline reuptake inhibitors (SNRI)2; selective serotonin reuptake inhibitors (SSRI)3 4 - Persistent sexual dysfunction after drug withdrawal (EPITT no 19277)
Croatian: Inhibitori ponovne pohrane serotonina i noradrenalina (SNRI)2; selektivni inhibitori ponovne pohrane serotonina (SSRI)3 4 - Perzistentan poremećaj seksualne funkcije nakon prekida primjene lijeka (EPITT br. 19277)
English: Date of first authorisation: 15 September 2008.
Croatian: Datum prvog odobrenja: 15. rujan 2008.
English: The following information is intended for healthcare professionals only
Croatian: Sljedeće informacije namijenjene su samo za zdravstvene radnike
English: Do not warm Tevagrastim in any other way (for example, do not warm it in a microwave or in hot water).
Croatian: Ne zagrijavajte Tevagrastim na bilo koji drugi način (na primjer, ne zagrijavajte ju u mikrovalnoj pećnici ili vrućoj vodi).
English: 08409 Vilnius Lithuania
Croatian: 08409 Vilnius
English: Your doctor may want to monitor you closely , see section 4 of the package leaflet.
Croatian: Vaš liječnik će Vas možda željeti pažljivo pratiti, vidjeti dio 4. upute o lijeku.
English: Tell your doctor or pharmacist if you are using have recently used or might use any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: Administer the dose as per standard protocol.
Croatian: Primijenite lijek po standardnom protokolu.
English: You, or people caring for you, can be taught how to give subcutaneous injections so that you can continue your treatment at home.
Croatian: Vi, ili osobe koje se brinu o Vama, možete naučiti kako davati potkožne (supkutane) injekcije tako da možete nastaviti liječenje kod kuće.
English: The needle safety guard will rapidly move to cover the needle (see picture 7).
Croatian: Zaštita za iglu će brzo prekriti iglu (vidjeti sliku 7).
English: How long will I have to take Tevagrastim?
Croatian: Koliko dugo moram uzimati Tevagrastim?
English: Before you inject Tevagrastim you must do the following:
Croatian: Prije nego primijenite Tevagrastim injekciju morate učiniti slijedeće:
English: Talk to your doctor, pharmacist or nurse before using Tevagrastim
Croatian: Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego primijenite Tevagrastim.
English: - in patients with advanced HIV infection which will help reduce the risk of infections.
Croatian: - u bolesnika s uznapredovalom HIV infekcijom, što će pomoći smanjiti rizik od infekcija.
English: This section contains information on how to give yourself an injection of Tevagrastim.
Croatian: Ovo poglavlje sadrži informacije o tome kako možete sami sebi davati injekcije lijeka Tevagrastim.
English: Try to self-inject at approximately the same time every day.
Croatian: Pokušajte samostalno primijeniti injekciju svaki dan u isto vrijeme.
English: Other medicines and Tevagrastim
Croatian: Drugi lijekovi i Tevagrastim
English: - osteoporosis (bone disease).
Croatian: - osteoporozu (bolest kostiju).
English: What Tevagrastim looks like and contents of the pack
Croatian: Kako Tevagrastim izgleda i sadržaj pakiranja
English: Do not release the pressure on the plunger!
Croatian: Ne popuštajte pritisak na klip!
English: Teva Pharmaceuticals Polska Sp. z o.o.
Croatian: Polska Teva Pharmaceuticals Polska Sp. z o.o.
English: Accidental exposure to freezing temperatures does not adversely affect the stability of Tevagrastim.
Croatian: Slučajno izlaganje temperaturama zamrzavanja ne utječe štetno na stabilnost Tevagrastima.
English: If you develop or are likely to develop cancers of the blood, you should not use Tevagrastim, unless instructed by your doctor.
Croatian: Ako razvijete ili ste skloni razvoju raka krvi, ne smijete primjenjivati Tevagrastim osim ako Vas tako nije uputio liječnik.
English: Contents of the pack and other information Information for injecting yourself
Croatian: Sadržaj pakiranja i druge informacije Informacije za samostalno injiciranje
English: Tevagrastim is usually given as a daily injection into the tissue just under the skin (known as a subcutaneous injection).
Croatian: Tevagrastim se obično daje kao dnevna injekcija u tkivo neposredno ispod kože (poznata kao potkožna ili supkutana injekcija).
English: In view of the possible risk of microbial contamination, Tevagrastim syringes are for single use only.
Croatian: Imajući u vidu mogući rizik od mikrobiološke kontaminacije, štrcaljke s Tevagrastimom namijenjene su isključivo jednokratnoj uporabi.
English: Congenital neutropenia
Croatian: Kongenitalna neutropenija
English: Tevagrastim is a white blood cell growth factor (granulocyte colony stimulating factor) and belong to a group of medicines called cytokines.
Croatian: Tevagrastim je faktor rasta bijelih krvnih stanica (faktor stimulacije kolonije granulocita) i pripada skupini lijekova zvanih citokini.
English: Common (≥ 1/100 to
Croatian: (≥ 1/100 i
English: Tevagrastim contains sorbitol (E420).
Croatian: Tevagrastim sadrži sorbitol (E420).
English: Relative risk (95 % CI) of GvHD and TRM following treatment with G-CSF after bone marrow transplantation
Croatian: Relativni rizik (95 % CI) za GvHD i TRM nakon terapije G-CSF-om nakon transplantacije koštane srži Publikacija
English: Fertility Filgrastim did not affect reproductive performance or fertility in male or female rats (see section 5.3).
Croatian: Plodnost Filgrastim nije utjecao na reproduktivnu sposobnost ili plodnost u mužjaka i ženki štakora (vidjeti dio 5.3).
English: Check again to make sure the correct dose of Tevagrastim is in the syringe.
Croatian: Provjerite još jedanput da budete sigurni u točnu dozu lijeka Tevagrastim u štrcaljki.
English: Let go of the plunger.
Croatian: Pustite klip.
English: Contents of the pack and other information What Tevagrastim contains
Croatian: Sadržaj pakiranja i druge informacije Što Tevagrastim sadrži
English: If you use more Tevagrastim than you should
Croatian: Ako primijenite više lijeka Tevagrastim nego što ste trebali
English: - to increase the number of white blood cells if you suffer from severe chronic neutropenia to help prevent infections.
Croatian: - za povećanje broja bijelih krvnih stanica ako patite od teške kronične neutropenije, kako bi se pomoglo u borbi protiv infekcija;
English: Do not use any Tevagrastim that is left in the syringe.
Croatian: Ne primjenjujte Tevagrastim koji je ostao u štrcaljki.
English: Tevagrastim containing r-metHuG-CSF (filgrastim) causes marked increases in peripheral blood neutrophil counts within 24 hours, with minor increases in monocytes.
Croatian: Tevagrastim, koji sadrži r-metHuG-CSF (filgrastim), uzrokuje izrazit porast broja neutrofila u perifernoj krvi unutar 24 sata, i neznatan porast broja monocita.
English: If you become pregnant during Tevagrastim treatment, please inform your doctor.
Croatian: Ako ostanete trudni tijekom liječenja Tevagrastimom, obavijestite svog liječnika.
English: A reduction in the number of white blood cells (neutropenia) can occur for several reasons and makes your body less able to fight infection.
Croatian: Za što se Tevagrastim koristi Smanjenje broja bijelih krvnih stanica (neutropenija) može se javiti iz nekoliko razloga i čini Vaše tijelo manje sposobnim za borbu protiv infekcije.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Croatian: Nositelj odobrenja za stavljanje lijeka u promet će PSUR-eve za ovaj lijek podnositi u skladu s referentnim popisom datuma EU (EURD popis) predviđenom člankom 107.c stavkom 7 Direktive 2001/83/EZ i objavljenim na europskom internetskom portalu za lijekove.
English: Timing of leukapheresis: 1 or 2 leukapheresis on days 5 and 6 are often sufficient.
Croatian: Vrijeme i broj leukafereza: obično su dovoljne 1-2 leukafereze, 5. i 6. dan.
English: Teva Pharma Belgium N.V./S.A./AG, Belgique/Belgien
Croatian: Luxembourg/Luxemburg Teva Pharma Belgium N.V./S.A./AG,
English: There were no relevant differences between Tevagrastim and the reference product with regard to duration of severe neutropenia and incidence of febrile neutropenia.
Croatian: Nije bilo relevantnih razlika između Tevagrastima i referentnog pripravka u trajanju teške neutropenije ni u incidenciji febrilne neutropenije.
English: UAB Teva Baltics filiāle Latvijā
Croatian: UAB Teva Baltics Eesti filiaal
English: How do I prepare my Tevagrastim injection?
Croatian: Kako pripremiti Tevagrastim injekciju?
English: Leukapheresis should be started at day 5 and continued until day 6 if needed in order to collect 4 x 106 CD34+ cells/kg recipient bodyweight.
Croatian: Leukaferezu treba početi 5. dan i nastaviti do 6. dana, bude li potrebno, da se prikupi 4 x 106 CD34+-stanica/kg tjelesne težine primatelja.
English: A common side effect of Tevagrastim use is pain in your muscles or bones (musculoskeletal pain), which could be relieved by taking standard pain relief medicines (analgesics).
Croatian: Česta nuspojava primjene Tevagrastima je bol u mišićima ili kostima (mišićno-koštana bol), koja se može olakšati uzimanjem standardnih lijekova za ublažavanje boli (analgetika).