FrancophonIA/ELRC3.0 huggingface dataset:
English: Lantus 100 units/ml solution for injection in a vial Lantus 100 units/ml solution for injection in a cartridge Lantus SoloStar 100 units/ml solution for injection in a pre-filled pen
Croatian: Lantus 100 jedinica/ml otopina za injekciju u ulošku Lantus SoloStar 100 jedinica/ml otopina za injekciju u napunjenoj brizgalici
English: Lantus SoloStar 100 units/ml solution for injection in a pre-filled pen Insulin glargine
Croatian: Lantus SoloStar 100 jedinica/ml otopina za injekciju u napunjenoj brizgalici inzulin glargin
English: Lantus 100 units/ml solution for injection insulin glargine
Croatian: Lantus 100 jedinica/ml otopina za injekciju inzulin glargin
English: Once in use, vials may be stored for a maximum of 4 weeks not above 30°C.
Croatian: Ulošci u uporabi mogu se čuvati najdulje 4 tjedna na temperaturi do 30°C.
English: Retinopathy
Croatian: Simptomi
English: Consult your insulin pen instruction booklet for further details.
Croatian: Za detaljne informacije pogledajte knjižicu s uputama za uporabu brizgalice.
English: Pre-filled pens in use or carried as a spare may be stored for a maximum of 4 weeks not above 30°C and away from direct heat or direct light.The pen in use must not be stored in the refrigerator Do not use it after this time period.
Croatian: Napunjene brizgalice u uporabi ili rezervne brizgalice mogu se čuvati najdulje 4 tjedna na temperaturi do 30°C, zaštićene od izvora topline i izravne svjetlosti.
English: Step 6.
Croatian: 4. korak Odabir doze
English: Read the package leaflet before use.
Croatian: Pregledajte uložak prije nego što ga upotrijebite.
English: This helps prevent:
Croatian: One obuhvaćaju bolesnike:
English: HYPERGLYCAEMIA (high blood sugar levels)
Croatian: - ako imate hiperglikemiju (visoku razinu šećera u krvi),
English: Ελλάδα sanofi-aventis AEBE Τηλ: +30 210 900 16 00
Croatian: Τηλ: +30 210 900 16 00
English: What Lantus contains
Croatian: Sadržaj pakiranja i druge informacije Što Lantus sadrži
English: Do not use SoloStar if you notice particles in it. Only use SoloStar if the solution is clear, colourless and waterlike.
Croatian: Smijete ga upotrijebiti samo ako je otopina bistra, bezbojna i vodenasta.
English: Subcutaneous use Open here
Croatian: Otvoriti ovdje
English: Select the dose
Croatian: UPUTA O LIJEKU
English: Lantus 100 units/ml solution for injection in a cartridge Insulin glargine
Croatian: Lantus 100 jedinica/ml otopina za injekciju u ulošku inzulin glargin
English: Injection site reactions
Croatian: Opći poremećaji i reakcije na mjestu primjene reakcije na mjestu injiciranja edem
English: It usually appears between 40 and 50 years of age.
Croatian: Obično se javlja u dobi između 40 i 50 godina.
English: The absolute risk reduction was 4.2%.
Croatian: Smanjenje apsolutnog rizika iznosilo je 4,2%.
English: The median follow-up duration was 22.9 months.
Croatian: Medijan perioda praćenja bio je 22,9 mjeseci.
English: Ask your pharmacist how to throw away medicines you no longer use.
Croatian: Pitajte svog ljekarnika kako bacati lijekove koje više ne koristite.
English: Luminous phenomena (phosphenes)
Croatian: Svjetlosni fenomeni (fosfeni)
English: Do not take a double dose to make up for the forgotten dose.
Croatian: Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: The higher than approved dose used in the study did not fully explain these findings.
Croatian: Veća doza lijeka od odobrene korištena u ispitivanju nije u potpunosti objasnila ove rezultate.
English: In this way Corlentor helps to control and reduce the number of angina attacks.
Croatian: Na taj način, Corlentor pomaže u kontroliranju i smanjenju broja napadaja angine.
English: Uncontrolled blood pressure
Croatian: Nekontrolirani krvni tlak
English: The potential risk for humans is unknown.
Croatian: Nije poznato koliki je potencijalni rizik primjene u ljudi.
English: About 4% of an oral dose is excreted unchanged in urine.
Croatian: Oko 4% oralne doze izlučuje se nepromijenjeno u urinu.
English: Corlentor should be taken during meals.
Croatian: Corlentor treba uzimati tijekom obroka.
English: Headache, generally during the first month of treatment
Croatian: Glavobolja, obično tijekom prvog mjeseca liječenja
English: If you forget to take a dose of Corlentor, take the next dose at the usual time.
Croatian: Ako zaboravite uzeti jednu dozu Corlentora, uzmite sljedeću dozu u uobičajeno vrijeme.
English: Do not throw away any medicine via wastewater or household waste.
Croatian: Nikada nemojte nikakve lijekove bacati u otpadne vode ili kućni otpad.
English: ibutilide, amiodarone).
Croatian: ibutilid, amiodaron).
English: Like all medicines, this medicine can cause side effects, although not everybody gets them.
Croatian: Kao i svi lijekovi, ovaj lijek može uzrokovati nuspojave, iako se neće javiti kod svakoga.
English: Hazard ratio [95% CI]
Croatian: Omjer ugroženosti [95% CI]
English: If this happens, contact your doctor immediately.
Croatian: Ako se to dogodi, odmah se obratite liječniku.
English: Other medicines and Corlentor
Croatian: Drugi lijekovi i Corlentor
English: Elevated creatinine in blood
Croatian: Povišena vrijednost kreatinina u krvi
English: What Corlentor is and what it is used for
Croatian: Što je Corlentor i za što se koristi
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, ako ste nedavno uzimali ili biste mogli uzeti bilo koje druge lijekove.
English: Children Corlentor is not intended for use in children and adolescents younger than 18 years.
Croatian: Corlentor nije namijenjen djeci ni mladeži mlađoj od 18 godina.
English: The MAH shall complete, within the stated timeframe, the below measures:
Croatian: Nositelj odobrenja će dovršiti, unutar navedenog vremenskog roka, niže navedenu mjeru:
English: All phosphenes resolved during or after treatment, of which a majority (77.5%) resolved during treatment.
Croatian: Svi su se fosfeni povukli tijekom ili nakon liječenja, od čega se većina (77,5%) povukla tijekom liječenja.
English: About stable angina pectoris (usually referred to as “angina”):
Croatian: O stabilnoj angini pektoris (koja se obično naziva “anginom”):
English: Very rare: Irregular heart beats.
Croatian: Vrlo rijetko: Nepravilni otkucaji srca.
English: Tablets must be taken orally twice daily, i.e. once in the morning and once in the evening during meals (see section 5.2).
Croatian: Tablete se moraju uzimati peroralno dva puta na dan, tj. jedanput ujutro i jedanput uvečer tijekom obroka (vidjeti dio 5.2).
English: Your doctor will decide the right dose for you.
Croatian: Liječnik će odrediti koja je prava doza za Vas.
English: The calendar printed on the blister containing the tablets should help you remember when you last took a tablet of Corlentor.
Croatian: Kalendar otisnut na blister pakovanju koje sadržava tablete, trebao bi Vam pomoći da zapamtite, kada ste zadnji put uzeli tabletu Corlentora.
English: - This medicine has been prescribed for you.
Croatian: Ovaj je lijek propisan Vama.
English: The safety and efficacy of ivabradine in children aged below 18 years have not yet been established.
Croatian: Sigurnost i djelotvornost ivabradina u djece starosti do 18 godina nisu još ustanovljene.
English: This lowers the heart's need for oxygen especially in the situations when an angina attack is more likely to happen.
Croatian: Time se smanjuje potreba srca za kisikom, osobito u situacijama kada postoji veća vjerojatnost da će doći do napadaja angine.
English: If you are pregnant and have taken Corlentor, talk to your doctor.
Croatian: Ako ste trudni, a uzeli ste Corlentor, obratite se liječniku.
English: Modification in the heart functioning (the symptoms are a slowing down of the heart rate).
Croatian: Promjene u radu srca (simptomi su usporenje otkucaja srca).
English: If this happens to you, be careful when driving or using machines at times when there could be sudden changes in light intensity, especially when driving at night.
Croatian: Ako se to dogodi Vama, budite pažljivi kada upravljate vozilom ili radite za strojevima u vrijeme kada bi moglo doći do iznenadnih promjena intenziteta svjetla, osobito tijekom upravljanja vozilom po noći.
English: Angina is more likely to happen when the heart beats faster in situations such as exercise, emotion, exposure to the cold or after eating.
Croatian: Veća je vjerojatnost da će angina nastupiti kada srce radi brže u situacijama kao što je fizički napor, emocije, izloženost hladnoći ili nakon jela.
English: Ivabradine has been studied in clinical trials involving nearly 45,000 participants.
Croatian: Ivabradin je ispitan u kliničkim ispitivanjima u kojima je sudjelovalo gotovo 45 000 osoba.
English: 92284 Suresnes cedex - France
Croatian: 92284 Suresnes cedex - Francuska
English: Women that need treatment with ivabradine should stop breast-feeding, and choose for another way of feeding their child.
Croatian: Žene kojima je neophodno liječenje s ivabradinom moraju prestati dojiti, i odabrati drugi način hranjenja djeteta.
English: Other long-term repeat dose and carcinogenicity studies revealed no clinically relevant changes.
Croatian: U drugim dugoročnim ispitivanjima s ponovljenim dozama i ispitivanjima kancerogenosti nisu otkrivene klinički relevantne promjene.
English: Luminous visual phenomena (brief moments of increased brightness, most often caused by sudden changes in light intensity).
Croatian: Svjetlosni vidni fenomeni (kratki trenuci pojačane svjetlosti, najčešće uzrokovani iznenadnim promjenama intenziteta svjetla).
English: Bradycardia was reported by 3.3% of patients particularly within the first 2 to 3 months of treatment initiation.
Croatian: Bradikardija je zabilježena u 3,3% bolesnika osobito unutar prva 2 do 3 mjeseca uvođenja liječenja.
English: The usual dose is one tablet in the morning and one tablet in the evening.
Croatian: Uobičajena doza je jedna tableta ujutro, a jedna tableta uvečer.
English: Combination with calcium channel blockers
Croatian: Kombinacija s blokatorima kalcijevih kanala
English: The effects on blood pressure and peripheral vascular resistance were minor and not clinically significant.
Croatian: Učinci na krvni tlak i periferni vaskularni otpor bili su minorni i nisu bili klinički signifikantni.
English: Studies in animals have shown reproductive toxicity.
Croatian: Ispitivanja na životinjama pokazala su da postoje toksični učinci na reprodukciju.
English: If you think that the effect of Corlentor is too strong or too weak, talk to your doctor or pharmacist.
Croatian: Ako mislite da je učinak Corlentora prejak ili preslab, razgovarajte s liječnikom ili ljekarnikom.
English: This leads to a reduction in cardiac workload and myocardial oxygen consumption.
Croatian: To dovodi do redukcije radnog opterećenja srca i potrošnje kisika u miokardu.
English: Do not take Corlentor - if you are allergic to ivabradine or any of the other ingredients of this medicine (listed in section
Croatian: Nemojte uzimati Corlentor - ako ste alergični na ivabradin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6);
English: Caution should be exercised in patients with retinitis pigmentosa.
Croatian: Potreban je oprez u bolesnika s retinitis pigmentosa.
English: What Corlentor is and what it is used for What you need to know before you take Corlentor How to take Corlentor
Croatian: Što je Corlentor i za što se koristi Što morate znati prije nego počnete uzimati Corlentor Kako uzimati Corlentor
English: Arklow - Co. Wicklow - Ireland
Croatian: Wicklow - Irska
English: They generally occur within the first two months of treatment after which they may occur repeatedly and resolve during or after treatment
Croatian: Obično se javljaju unutar prva dva mjeseca liječenja nakon čega se mogu ponavljano javljati i nestati tijekom ili nakon liječenja.
English: 14 film-coated tablets [28 film-coated tablets] [56 film-coated tablets] [84 film-coated tablets] [98 film-coated tablets] [100 film-coated tablets] [112 film-coated tablets]
Croatian: 14 filmom obloženih tableta [28 filmom obloženih tableta] [56 filmom obloženih tableta] [84 filmom obloženih tableta] [98 filmom obloženih tableta] [100 filmom obloženih tableta] [112 filmom obloženih tableta]
English: Corlentor contains lactose
Croatian: Corlentor sadrži laktozu
English: What you need to know before you take Corlentor
Croatian: Što morate znati prije nego počnete uzimati Corlentor
English: AV 1st degree block (ECG prolonged PQ interval)
Croatian: AV blok prvog stupnja (produžen PQ interval u EKG-u)
English: If you take more Corlentor than you should
Croatian: Ako uzmete više Corlentora nego što ste trebali:
English: The treatment has to be initiated only in patient with stable heart failure.
Croatian: Liječenje treba započeti samo u bolesnika sa stabilnim zatajenjem srca.
English: Ivabradine has no influence on the ability to use machines.
Croatian: Ivabradin ne utječe na sposobnost rada sa strojevima.
English: Under physiological conditions, ivabradine is rapidly released from tablets and is highly water-soluble (>10 mg/ml).
Croatian: U fiziološkim se uvjetima ivabradin brzo oslobađa iz tableta te je vrlo topljiv u vodi (>10 mg/ml).
English: Hypertensive patients requiring blood pressure treatment modifications.
Croatian: Bolesnici s hipertenzijom koji zahtijevaju promjenu liječenja visokog krvnog tlaka.
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential.
Croatian: Neklinički podaci ukazuju da nema posebnih opasnosti za ljude na temelju standardnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti i kancerogenog potencijala.
English: In addition, discontinuation of treatment should be considered if there is only limited symptomatic response and when there is no clinically relevant reduction in resting heart rate within three months.
Croatian: Nadalje, prekid liječenja potrebno je razmotriti kada postoji samo ograničeni odgovor na simptomatsko liječenje i kada ne postoji kliničko značajno smanjenje srčane frekvencije unutar 3 mjeseca liječenja.
English: They are usually triggered by sudden variations in light intensity.
Croatian: Obično ih potiču iznenadne promjene intenziteta svjetla.
English: Other side effects have also been reported:
Croatian: Druge nuspojave su također zabilježene: Često:
English: Date of latest renewal: 25/10/2010
Croatian: Datum posljednje obnove: 25/10/2010
English: These episodes occurred most frequently shortly after blood pressure treatment was modified, were transient, and did not affect the treatment effect of ivabradine.
Croatian: Ove epizode su se najčešće pojavile ubrzo nakon promjene liječenja visokog tlaka, bile su prolazne i nisu utjecale na terapijski učinak ivabradina.
English: Abbreviations for days of the week
Croatian: Kratice za dane u tjednu
English: s r.o.
Croatian: Z O.O.
English: The absolute bioavailability of the film-coated tablets is around 40%, due to first-pass effect in the gut and liver.
Croatian: Apsolutna bioraspoloživost filmom obloženih tableta iznosi oko 40%, zbog učinka prvog prolaza u crijevu i jetri.
English: No influence on glucose or lipid metabolism was observed.
Croatian: Nije zapažen utjecaj na glukozu ili metabolizam lipida.
English: If the combination appears necessary, close cardiac monitoring is needed.
Croatian: Ukoliko se čini da je ta kombinacija potrebna, rad srca treba pažljivo pratiti.
English: Phosphenes were generally reported to be of mild to moderate intensity.
Croatian: Općenito je zabilježeno da su fosfeni bili blaga do umjerena intenziteta.
English: Stable angina is a heart disease which happens when the heart does not receive enough oxygen.
Croatian: Stabilna angina pektoris jest bolest srca koja nastaje kada srce ne prima dovoljno kisika.
English: If there is no improvement in symptoms of angina within 3 months after start of treatment, treatment of ivabradine should be discontinued.
Croatian: Ukoliko se ne postigne poboljšanje simptoma unutar 3 mjeseca od početka liječenja, liječenje ivabradinom se mora prekinuti.
English: Absorption and bioavailability
Croatian: Absorpcija i bioraspoloživost
English: Cytochrome P450 3A4 (CYP3A4)
Croatian: Citokrom P450 3A4 (CYP3A4)
English: Ivabradine is the S-enantiomer with no bioconversion demonstrated in vivo.
Croatian: Ivabradin je S-enantiomer, a biokonverzija nije demonstrirana in vivo.
English: Food delayed absorption by approximately 1 hour, and increased plasma exposure by 20 to 30 %.
Croatian: Hrana usporava apsorpciju za oko 1 sat, te povećava koncentraciju u plazmi za 20 do 30 %.
English: These studies have shown embryotoxic and teratogenic effects (see section 5.3).
Croatian: Ispitivanja su pokazala embriotoksične i teratogene učinke (vidjeti dio 5.3).
English: Hypotension,
Croatian: Hipotenzija,
English: In dogs given ivabradine (doses of 2, 7 or 24 mg/kg/day) for one year, reversible changes in retinal function were observed but were not associated with any damage to ocular structures.
Croatian: U pasa koji su godinu dana dobivali ivabradin (doze od 2, 7 ili 24mg/kg/dan), zapažene su reverzibilne promjene funkcije mrežnice, no nisu bile povezane s oštećenjem okularnih struktura.
English: Pharmacokinetic/pharmacodynamic (PK/PD) relationship
Croatian: Farmakokinetički/Farmakodinamički (PK/PD) odnos
English: The metabolism of this active metabolite also involves CYP3A4.
Croatian: Metabolizam toga aktivnog metabolita također obuhvaća CYP3A4.
English: Treatment effect on the primary composite endpoint, its components and secondary endpoints
Croatian: Učinak liječenja na primarni kompozitni ishod, njegove pojedine komponente i sekundarne ishode
English: The intake of the tablet during meals is recommended in order to decrease intra-individual variability in exposure (see section 4.2).
Croatian: Preporučuje se tablete uzimati tijekom obroka, da bi se smanjila intraindividualna varijabilnost koncentracije (vidjeti dio 4.2).
English: Concomitant use with precaution
Croatian: Istodobna primjena s oprezom
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKOVANJU KUTIJA
English: The tablets are available in calendar packs (Aluminium/PVC blisters) of 14, 28, 56, 84, 98, 100 or 112 tablets.
Croatian: Tablete su dostupne u kalendarskim pakovanjima (aluminij/PVC blisterima) od 14, 28, 56, 84, 98, 100 ili 112 tableta.
English: If you still have angina symptoms and if you have tolerated the 5 mg twice daily dose well, the dose may be increased.
Croatian: Ukoliko i dalje imate simptome angine i dobro podnosite dozu od 5 mg dva puta na dan, doza se može povećati.
English: Since tablets contain lactose, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Croatian: Budući da tablete sadrže laktozu, bolesnici s rijetkim nasljednim poremećajem nepodnošenja galaktoze, nedostatkom Lapp laktaze ili glukoza-galaktoza malapsorpcijom ne smiju uzimati ovaj lijek.
English: It is recommended that the treating physician should be experienced in the management of chronic heart failure.
Croatian: Preporučuje se da liječnik koji provodi liječenje ima iskustva u vođenju liječenja kroničnog zatajenje srca.
English: Calendar packs containing 14, 28, 56, 84, 98, 100 or 112 film-coated tablets.
Croatian: Kalendarska pakiranja sadrže 14, 28, 56, 84, 98, 100 ili 112 filmom obloženih tableta.
English: Aluminium/PVC blister packed in cardboard boxes.
Croatian: 6.5 Vrsta i sadržaj spremnika Aluminij/PVC blisteri pakirani u kartonske kutije.
English: Always take this medicine exactly as your doctor or pharmacist has told you.
Croatian: Kako uzimati Corlentor Uvijek uzmite ovaj lijek točno onako kako Vam je rekao Vaš liječnik ili ljekarnik.
English: They can also be described as a halo, coloured flashes, image decomposition or multiple images.
Croatian: Mogu se također opisati kao aureola, raznobojne blijeskove, rastavljanje slike ili višestruke slike.
English: In this study, the antianginal and anti-ischaemic benefits of ivabradine were confirmed in patients aged 65 years or more.
Croatian: U toj su studiji potvrđene antianginalne i antiishemijske prednosti ivabradina u bolesnika od 65 godina i starijih.
English: Women of child-bearing potential should use appropriate contraceptive measures during treatment (see section 4.3).
Croatian: Žene generativne dobi trebaju koristiti prikladne mjere kontracepcije tijekom liječenja (vidjeti dio 4.3).
English: It is used in adult patients who do not tolerate or cannot take heart medicines called beta-blockers.
Croatian: Lijek se koristi kod odraslih bolesnika koji ne podnose ili ne smiju uzimati lijekove za srce koji se zovu beta- blokatori.
English: Ivabradine is eliminated with a main half-life of 2 hours (70-75% of the AUC) in plasma and an effective half-life of 11 hours.
Croatian: Ivabradin se eliminira uz poluvrijeme eliminacije od 2 sata (70-75% AUC) u plazmi i efektivno poluvrijeme eliminacije od 11 sati.
English: Other secondary endpoints: - All cause death - Death from HF - Hospitalisation for any cause - Hospitalisation for CV reason
Croatian: Drugi sekundarni ishodi: - smrt zbog svih uzroka - smrt zbog zatajenja srca - hospitalizacija zbog bilo kojeg uzroka - hospitalizacija zbog KV uzroka
English: The total clearance is about 400 ml/min and the renal clearance is about 70 ml/min.
Croatian: Ukupni klirens je oko 400 ml/min, a renalni klirens oko 70 ml/min.
English: Servier Polska SP. Z O.O.
Croatian: Servier Polska SP.
English: Reproductive toxicity studies showed no effect of ivabradine on fertility in male and female rats.
Croatian: Ispitivanja reproduktivne toksičnosti nisu pokazala učinak ivabradina na plodnost mužjaka i ženki štakora.
English: At higher doses, the decrease in heart rate is no longer proportional to ivabradine plasma concentrations and tends to reach a plateau.
Croatian: Uz veće doze, usporenje srčane frekvencije više nije proporcionalno koncentracijama ivabradina u plazmi i teži dosizanju platoa.
English: Patients received standard care including beta-blockers (89 %), ACE inhibitors and/or angiotensin II antagonists (91 %), diuretics (83 %), and anti-aldosterone agents (60 %).
Croatian: Bolesnici su liječeni standardnim pristupom uključujući beta-blokatore (89%), inhibitore ACE i/ili antagoniste angiotenzina II (91%), diuretike (83%) i antagoniste aldosterona (60%).
English: The European Medicines Agency has waived the obligation to submit the results of studies with Corlentor in all subsets of the paediatric population in the treatment of angina pectoris.
Croatian: Europska agencija za lijekove je izuzela obvezu podnošenja rezultata ispitivanja lijeka Corlentor u svim podskupinama pedijatrijske populacije u liječenju angine pektoris.
English: Ivabradine (N=3241) n (%)
Croatian: Ivabradin (N=3241)
English: Les Laboratoires Servier 50, rue Carnot 92284 Suresnes cedex France
Croatian: Les Laboratoires Servier 50, rue Carnot 92284 Suresnes cedex Francuska
English: Palpitations, supraventricular extrasystoles
Croatian: Palpitacija, supraventrikularne ekstrasistole
English: It is also used in combination with beta-blockers in adult patients whose condition is not fully controlled with a beta-blocker.
Croatian: Također se lijek koristi u kombinaciji s beta-blokatorima kod odraslih bolesnika čije stanje nije u potpunosti kontrolirano s beta-blokatorima.
English: Phosphenes may also be described as a halo, image decomposition (stroboscopic or kaleidoscopic effects), coloured bright lights, or multiple image (retinal persistency).
Croatian: Fosfeni se mogu također opisati kao aureola, rastavljanje slike (stroboskopski ili kaleidoskopski učinak), žarka svjetlost raznih boja, ili višestruke slike (perzistencija retine).
English: Marketing Authorisation Holder: Les Laboratoires Servier 50, rue Carnot
Croatian: Les Laboratoires Servier 50, rue Carnot