FrancophonIA/ELRC3.0 huggingface dataset:
English: A definitive mechanism of action of peginterferon beta-1a in multiple sclerosis (MS) is not known.
Icelandic: Sértækur verkunarháttur peginterferóns beta-1a í MS-sjúkdómi er ekki þekktur.
English: - Packs can be taken out of the fridge and then put back in a fridge more than once if you need to. - Make sure the time the syringes spend out of a fridge is no more than 30 days in total.
Icelandic: - Pakkningar má taka úr kæli og setja aftur í kælinn oftar en einu sinni ef þörf krefur.
English: • Slowly push the plunger all the way down until syringe is empty (See Figure I).
Icelandic: Þrýstu rólega á stimplinn alla leið niður þangað til sprautan er tóm (sjá mynd I).
English: (frequency cannot be estimated from the available data) - Pulmonary arterial hypertension: A disease of severe narrowing of the blood vessels in the lungs resulting in high blood pressure in the blood vessels that carry blood from the heart to the lungs.
Icelandic: Sjúkdómur með alvarlegri þrengingu í lungnaæðum sem leiðir til hækkunar á blóðþrýstingi í æðum sem flytja blóð frá hjarta til lungna.
English: The recommended dose of Plegridy is 125 micrograms injected subcutaneously every 2 weeks (14 days).
Icelandic: Ráðlagður skammtur af Plegridy eru 125 míkrógrömm sem gefin eru undir húð á tveggja vikna (14 daga) fresti.
English: Plegridy 125 mcg injection peginterferon beta-1a SC
Icelandic: Plegridy 125 µg stungulyf peginterferón beta-1a s.c.
English: Patients should be advised to immediately report any symptoms of depression and/or suicidal ideation to their prescribing physician.
Icelandic: Ráðleggja skal sjúklingum að greina lækninum þegar í stað frá ef þeir verða varir við þunglyndiseinkenni og/eða sjálfsvígshugsanir.
English: Do not pull back on the plunger.
Icelandic: Ekki draga sprautustimpilinn upp.
English: This medicine contains less than 1 mmol sodium (23 mg), that is to say it is essentially “sodium-free”.
Icelandic: Lyfið inniheldur minna en 1 mmól af natríum (23 mg), þ.e.a.s. er sem næst natríumlaust.
English: Supplies needed for your plegridy injection
Icelandic: Útbúnaður sem þarf fyrir Plegridy inndælingu
English: Peginterferon beta-1a has not been tested for reproductive toxicity in pregnant animals.
Icelandic: Peginterferón beta-1a hefur ekki verið prófað með tilliti til eituráhrifa á æxlun hjá þunguðum dýrum.
English: The other ingredients are: Sodium acetate trihydrate, acetic acid glacial, arginine hydrochloride, polysorbate 20 and water for injections (see Section 2 “Plegridy contains Sodium”).
Icelandic: Natríumasetat þríhýdrat, ísedik, arginín hýdróklóríð, pólýsorbat 20 og vatn fyrir stungulyf (sjá kafla 2 „Plegridy inniheldur natríum“).
English: External heat sources such as hot water must not be used to warm Plegridy.
Icelandic: Ekki má nota hitagjafa á borð við heitt vatn til að hita Plegridy.
English: How to use Plegridy
Icelandic: Hvernig nota á Plegridy
English: Re-capping could cause the pen to lock.
Icelandic: Ef hettan er sett aftur á gæti lyfjapenninn læst sér.
English: Cases of TMA, manifested as thrombotic thrombocytopenic purpura (TTP) or haemolytic uraemic syndrome (HUS), including fatal cases, have been reported with interferon beta products.
Icelandic: Tilkynnt hefur verið um tilfelli segaöræðakvilla sem koma fram sem blóðflagnafæðarpurpuri með segamyndun (TTP) eða þvageitrunarblóðlýsa (HUS), þ.m.t. banvæn tilfelli við meðferð með interferón beta lyfjum.
English: Second injection: 94 micrograms, choose blue pen
Icelandic: 94 míkrógrömm, veldu bláan penna
English: Date of first authorisation: 18 July 2014 Date of latest renewal: 25 March 2019
Icelandic: 25. mars 2019
English: • For the first injections, you can use the record table printed on the inside of the lid of the
Icelandic:  Fyrir fyrstu inndælingarnar getur þú notað skráningartöfluna sem prentuð er innan á lok upphafspakkningarinnar.
English: P-value p=0.0007
Icelandic: P-gildi p=0,0007
English: Prompt treatment of nephrotic syndrome is required and discontinuation of treatment with Plegridy should be considered.
Icelandic: Nýrungaheilkenni krefst tafarlausrar meðferðar og íhuga skal stöðvun meðferðar með Plegridy.
English: Dose 3
Icelandic: Skref 3:
English: These blood tests will be in addition to the tests which are normally done to monitor your MS. - The functioning of your thyroid gland will be checked regularly or whenever thought necessary by your doctor.
Icelandic: Þessi blóðpróf bætast við þau próf sem eru venjulega gerð til að fylgjast með MS sjúkdómi þínum.
English: To minimise the risk of injection site reactions patients should be instructed in the use of an aseptic injection technique.
Icelandic: Til að draga úr hættu á aukaverkunum á stungustað skal leiðbeina sjúklingum að viðhafa smitgát við sprautun.
English: 47% ≥2 relapses in prior year
Icelandic: 47% ≥ 2 köst síðasta árið 38% a.m.k.
English: Plegridy 63 mcg injection Plegridy 94 mcg injection peginterferon beta-1a SC
Icelandic: Plegridy 63 µg stungulyf Plegridy 94 µg stungulyf peginterferón beta-1a s.c.
English: It is not known whether peginferferon beta-1a is secreted in human milk.
Icelandic: Ekki er vitað hvort peginterferón beta-1a skilst út í móðurmjólk.
English: Pre-Filled Syringe Initiation Pack
Icelandic: Merkimiði á áfylltri sprautu í upphafspakkningu
English: - Irritation at an injection site, which can lead to skin and tissue damage (injection site necrosis).
Icelandic: - Ertingu á stungustað sem getur leitt til húð- og vefjaskemmda (drep á stungustað).
English: 1 pre-filled syringe of 63 micrograms 1 pre-filled syringe of 94 micrograms
Icelandic: 1 áfyllt sprauta með 63 míkrógrömmum 1 áfyllt sprauta með 94 míkrógrömmum
English: You should see a yellow plunger.
Icelandic: Þú ættir að sjá gulan stimpil.
English: Do not inject directly into your belly button.
Icelandic: Ekki gefa inndælinguna beint í naflann.
English: This medicinal product contains less than 1 mmol (23 mg) sodium, that is to say it is essentially “sodium-free”.
Icelandic: Lyfið inniheldur minna en 1 mmól (23 mg) af natríum, þ.e.a.s. er sem næst natríumlaust.
English: P-value p=0.0003
Icelandic: P-gildi p=0,0003
English: The following may occur: Blood clots in the small blood vessels that can affect your kidneys (thrombotic thrombocytopenic purpura or haemolytic uremic syndrome).
Icelandic: Blóðtappar geta myndast í litlum æðum og þeir geta haft áhrif á nýrun (blóðflagnafæðarpurpuri með segamyndun eða rauðalos-þvageitrunarheilkenni).
English: Cases of nephrotic syndrome with different underlying nephropathies including collapsing focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), membranoproliferative glomerulonephritis (MPGN) and membranous glomerulopathy (MGN) have been reported during treatment with interferon-beta products.
Icelandic: Tilkynnt hefur verið um tilfelli nýrungaheilkennis með mismunandi undirliggjandi nýrnakvillum, þ. á. m. samfallsafbrigði staðbundins nýrahnoðraherslis í geira (FSGS), nýrnakvilla með lágmarksbreytingum (MCD), himnu- og fjölgunarnýrahnoðrabólgu (MPGN) og nýrahnoðrakvilla í himnu (MGN) við meðferð með interferón beta lyfjum.
English: The dose indicates the quantity of the interferon beta-1a moiety of peginterferon beta-1a without consideration of the PEG moiety attached.
Icelandic: Skammturinn tilgreinir magn interferón beta-1a hlutans í peginterferón beta-1a án tillits til hins viðtengda PEG-hluta.
English: PARTICULARS TO APPEAR ON THE INTERMEDIATE PACKAGING MULTIPACK INNER CARTON
Icelandic: INNRI UMBÚÐUM FJÖLPAKKNING INNRI ASKJA
English: - Store in a refrigerator (fridge) 2º-8ºC.
Icelandic: - Geymið í kæli við 2º - 8ºC.
English: How to store Plegridy
Icelandic: Hvernig geyma á Plegridy
English: Dosage schedule
Icelandic: FYRNINGARDAGSETNING
English: Syringe label
Icelandic: Flensulík einkenni
English: Box of two 125 microgram pre-filled pens (grey labelled pens) in a protective plastic tray.
Icelandic: Kassi með tveimur 125 míkrógramma áfylltum lyfjapennum (merktir gráir) í hlífðarplastbökkum.
English: Orange
Icelandic: Appelsínugul
English: • If needed, apply a gauze pad or adhesive bandage or plaster to the injection site.
Icelandic: Settu grisju eða plástur á stungustaðinn ef þörf er á.
English: Dose 2
Icelandic: Skref 2:
English: - Blood problems
Icelandic: - Blóðkvillar
English: If you use more Plegridy than you should
Icelandic: Ef notaður er stærri skammtur af Plegridy en mælt er fyrir um
English: Serious side effects - Liver problems
Icelandic: Alvarleg lifrar- eða nýrnavandamál
English: Efficacy of Plegridy has been demonstrated over placebo.
Icelandic: Sýnt hefur verið fram á virkni Plegridy fram yfir lyfleysu.
English: • Using one hand, hold the syringe by the glass barrel.
Icelandic: Haltu utan um glerhylki sprautunnar með annarri höndinni.
English: (common - may affect up to 1 in 10 people) If you: - Feel unusually sad, anxious or worthless or - Have thoughts about suicide
Icelandic: - Finnur fyrir óvenjulegri depurðar-, kvíða- eða gagnleysistilfinningu eða - Veltir fyrir þér að fremja sjálfsvíg
English: Flu-like symptoms are more common when you first start using Plegridy.
Icelandic: Flensulík einkenni eru algeng einkenni þegar notkun Plegridy er hafin.
English: The pharmacological properties of Plegridy are consistent with those of interferon beta-1a and are believed to be mediated by the protein portion of the molecule.
Icelandic: Lyfjafræðilegir eiginleikar Plegridy eru í samræmi við eiginleika interferón beta1a og eru taldir stýrast af próteinhluta sameindarinnar.
English: Decreased peripheral blood counts in all cell lines, including rare pancytopenia and severe thrombocytopenia, have been reported in patients receiving interferon beta.
Icelandic: Tilkynnt hefur verið um fækkun blóðkorna í útæðablóði í öllum frumulínum, þ.m.t. mjög sjaldgæfri blóðfrumnafæð og alvarlegri blóðflagnafæð, hjá sjúklingum sem fá meðferð með interferón beta.
English: • Plegridy pre-filled syringe is for subcutaneous injection (injection into skin).
Icelandic: Plegridy áfyllt sprauta er ætluð til inndælingar undir húð (inndælingar í húð).
English: Upon repeated dosing with peginterferon beta-1a of sexually mature female monkeys, effects on menstrual cycle length and progesterone levels were observed.
Icelandic: Þegar kynþroska apynjum voru gefnir endurteknir skammtar af peginterferóni beta-1a hafði það áhrif á lengd tíðahringsins og prógesterónmagn.
English: The pharmacokinetics of peginterferon beta-1a has not been evaluated in patients with hepatic insufficiency.
Icelandic: Lyfjahvörf peginterferón beta-1a hjá sjúklingum með skerta lifrarstarfsemi hafa ekki verið metin.
English: Do not share your Plegridy pen.
Icelandic: Ekki deila Plegridy lyfjapennanum með öðrum.
English: • Plegridy pre-filled syringe is for injecting the medicine under the skin only (subcutaneous)
Icelandic: Áfyllt Plegridy sprauta er eingöngu ætluð til inndælingar lyfsins undir húðina (inndæling undir húð).
English: (uncommon - may affect up to 1 in 100 people) If you get any of these:
Icelandic: (sjaldgæf - getur komið fyrir hjá allt að 1 af hverjum 100 einstaklingum)
English: Thrombotic microangiopathy (TMA) (class effects)
Icelandic: Segaöræðakvilli (TMA) (tengt lyfjaflokknum)
English: Toxicity
Icelandic: Eiturhrif
English: EXP If a refrigerator is not available, pens can be left at room temperature (up to 25°C) for up to 30 days.
Icelandic: EXP Ef kælir er ekki til staðar má geyma sprautur við stofuhita (upp að 25°C) í allt að 30 daga.
English: Plegridy binds to the type I interferon receptor on the surface of cells and elicits a cascade of intracellular events leading to the regulation of interferon-responsive gene expression.
Icelandic: I á yfirborði frumu og kallar þannig fram keðjuverkun innan frumunnar, sem leiðir til temprunar á interferón-móttækilegri genatjáningu.
English: Giving your injection Step 4: Choose and clean your injection site
Icelandic: Veldu og hreinsaðu stungustaðinn
English: Plegridy contains sodium
Icelandic: Plegridy með áfylltri sprautu
English: Race had no effect on the pharmacokinetics of peginterferon beta-1a in a population pharmacokinetic analysis.
Icelandic: Kynþáttur hafði engin áhrif á lyfjahvörf peginterferóns beta-1a samkvæmt þýðisgreiningu á lyfjahvörfum.
English: No information is available on the potential effects of peginterferon beta-1a on male fertility.
Icelandic: Engar upplýsingar liggja fyrir um hugsanleg áhrif peginterferóns beta-1a á frjósemi karla.
English: Pulmonary arterial hypertension has been seen at various time points during treatment, including several years after starting treatment with interferon beta-products.
Icelandic: Lungnaháþrýstingur hefur sést á ýmsum tímum meðan á meðferð stendur, þ.m.t. nokkrum árum eftir að meðferð með interferón beta lyfjum hófst.
English: The average molecular mass is approximately 44 kDa of which the protein moiety constitutes approximately 23 kDa.
Icelandic: Meðal mólmassinn er u.þ.b. 44 kDa, þar af er próteinhlutinn u.þ.b. 23 kDa.
English: Hypothyroidism and hyperthyroidism have been observed with the use of interferon beta products.
Icelandic: Of- og vanvirkni skjaldkirtils hefur komið fram við notkun interferón beta lyfja.
English: Sodium acetate trihydrate Acetic acid, glacial Arginine hydrochloride Polysorbate 20
Icelandic: Arginín hýdróklóríð Pólýsorbat 20
English: Step 7: Inject medicine
Icelandic: Skref 7: Fjarlægðu
English: When you are ready to inject, carefully follow the instructions in section 7 “Instructions for injecting Plegridy pre-filled syringe”, at the end of this leaflet.
Icelandic: Þegar þú ert tilbúin/n til að sprauta þig, skaltu fylgja nákvæmlega leiðbeiningunum í kafla 7
English: Plegridy 63 micrograms solution for injection in pre-filled syringe Plegridy 94 micrograms solution for injection in pre-filled syringe Plegridy 125 micrograms solution for injection in pre-filled syringe Plegridy 63 micrograms solution for injection in pre-filled pen Plegridy 94 micrograms solution for injection in pre-filled pen Plegridy 125 micrograms solution for injection in pre-filled pen
Icelandic: Plegridy 63 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Plegridy 94 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Plegridy 125 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna
English: Starting Plegridy
Icelandic: Að byrja að nota Plegridy
English: • Let the injection site dry before injecting the dose.
Icelandic: Láttu stungustaðinn þorna áður en skammtinum er dælt inn.
English: You will hear the clicking sounds start.
Icelandic: Þú munt heyra smelli.
English: Slight decreases in mean red blood cell (RBC) counts were observed in Plegridy treated patients.
Icelandic: Lítilsháttar lækkun á meðalfjölda rauðra blóðkorna kom fram hjá sjúklingum sem meðhöndlaðir voru með Plegridy.
English: Plegridy pre-filled pen must not be used if the liquid is coloured, cloudy, or contains floating particles.
Icelandic: Ekki má nota áfyllta Plegridy sprautu ef vökvinn er litaður, skýjaður eða inniheldur fljótandi agnir.
English: ┼ Class label for interferon products, see below Pulmonary arterial hypertension $ Class label for interferon products
Icelandic: ┼Áhrif tengd lyfjaflokki interferón lyfja, sjá lungnaháþrýsting hér neðar.
English: The clinical studies indicate that multiple sclerosis patients can receive Plegridy and corticosteroids during relapses.
Icelandic: Klínískar rannsóknir benda til þess að gefa megi MS-sjúklingum í afturför Plegridy og barkstera.
English: Pulmonary arterial hypertension
Icelandic: UPPLÝSINGAR MEÐ BLINDRALETRI
English: The mean steady state clearance of peginterferon beta-1a was 4.1 ± 0.4 L/hr.
Icelandic: Meðalgildi úthreinsunar peginterferón beta-1a var 4,1 ± 0,4 l/klst. við jafnvægi.
English: Ask your doctor, pharmacist, or nurse for instructions on throwing away used syringes.
Icelandic: Leitið ráða hjá lækninum, lyfjafræðingi eða hjúkrunarfræðingnum um hvernig heppilegast er að farga notuðum sprautum.
English: - Kidney problems including scarring that may reduce your kidney function
Icelandic: - Nýrnasjúkdómar, þ.m.t. örmyndun sem getur skert starfsemi nýrna
English: First injection: 63 micrograms, choose orange pen
Icelandic: 63 míkrógrömm, veldu appelsínugulan penna
English: You will be provided with an Initiation Pack containing your first 2 injections: one orange pen with Plegridy 63 micrograms (for day 0) and one blue pen with Plegridy 94 micrograms (for day 14).
Icelandic: Einn appelsínugulmerktan penna sem inniheldur 63 míkrógrömm af Plegridy (til notkunar á degi 0) og annan blámerktan penna með 94 míkrógrömmum af Plegridy (til notkunar á 14. degi).
English: Patients should be monitored for symptoms or signs of decreased peripheral blood counts (see section
Icelandic: Fylgst skal með einkennum eða merkjum um fækkun blóðkorna í útæðablóði hjá sjúklingum (sjá kafla 4.8).
English: Full dose injection: 125 micrograms, choose grey pen
Icelandic: 125 míkrógrömm, veldu gráan penna
English: Table 1: Titration schedule at initiation Dose
Icelandic: 1 stiga aukning frá upphafsgildi
English: Less than 1% of patients who received Plegridy during the placebo controlled phase of the ADVANCE study discontinued treatment due to flu-like symptoms.
Icelandic: Plegridy á meðan á samanburðarfasanum með lyfleysu í ADVANCE-rannsókninni stóð hættu meðferð vegna flensulíkra einkenna.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING MULTIPACK OUTER CARTON Pre-filled pen 125 mcg Multipack (with bluebox)
Icelandic: Áfylltur lyfjapenni 125 µg fjölpakkning (með „blue box“)
English: Do not re-cap the pen.
Icelandic: Ekki setja hettuna aftur á lyfjapennann.
English: Plegridy pre-filled syringe” before you start.
Icelandic: „Leiðbeiningar um inndælingu Plegridy með áfylltri sprautu“ áður en þú byrjar.
English: Do not use more than one pen per 14-day period (every 2 weeks).
Icelandic: Notaðu ekki meira en einn áfylltan penna á 14 daga tímabili (á 2 vikna fresti).
English: Hepatic transaminase abnormalities
Icelandic: Óeðlileg gildi lifrartransamínasa
English: rash or colour change - Changes in your blood which might cause tiredness or reduced ability to fight infection - Increases in liver enzymes in the blood (will show up in blood tests)
Icelandic: - Aukning á lifrarensímum í blóði (kemur fram í blóðprófum)
English: Step 2: Collect your supplies and wash your hands.
Icelandic: Taktu til útbúnaðinn og þvoðu þér um hendurnar a.
English: Solution for injection 2 pre-filled pens.
Icelandic: Stungulyf, lausn 2-áfylltir lyfjapennar.
English: Plegridy 125 micrograms solution for injection in pre-filled syringe Each pre-filled syringe contains 125 micrograms of peginterferon beta-1a* in 0.5 mL solution for injection.
Icelandic: Plegridy 125 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Hver áfylltur lyfjapenni inniheldur 125 míkrógrömm af peginterferón beta-1a* í 0,5 ml stungulyfi, lausn.
English: • Let the Plegridy pre-filled syringe warm to room temperature for at least 30 minutes.
Icelandic: Plegridy sprautuna hitna við stofuhita í að minnsta kosti 30 mínútur.
English: You will be provided with an Initiation Pack containing your first 2 injections: one orange syringe with Plegridy 63 micrograms (for day 0) and one blue syringe with Plegridy 94 micrograms (for day 14).
Icelandic: Eina sprautu merkt appelsínugul sem inniheldur 63 míkrógrömm af Plegridy (til notkunar á degi 0) og aðra blámerkta sprautu með 94 míkrógrömmum af Plegridy (til notkunar á 14. degi).
English: Do not share your Plegridy pre-filled syringe.
Icelandic: Ekki deila áfylltu Plegridy sprautunni með öðrum.
English: Hepatic injury
Icelandic: - Höfuðverkur
English: There are no data on the effects of peginferferon beta-1a on human fertility.
Icelandic: Engin gögn liggja fyrir um áhrif peginterferóns beta-1a á frjósemi manna.
English: Package leaflet: Information for the user Plegridy 63 micrograms solution for injection in pre-filled syringe Plegridy 94 micrograms solution for injection in pre-filled syringe Plegridy 125 micrograms solution for injection in pre-filled syringe peginterferon beta-1a
Icelandic: Upplýsingar fyrir notanda lyfsins Plegridy 63 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Plegridy 94 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Plegridy 125 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna peginterferón beta-1a
English: Neutralising antibodies have the potential to reduce clinical efficacy.
Icelandic: Hlutleysandi mótefni geta dregið úr klínískri virkni.
English: A 29 gauge, 0.5 inch staked needle is pre-affixed to the syringe.
Icelandic: 0,5 tommu nál af sporvídd 29 er áföst við sprautuna.
English: Each pre-filled syringe contains 125 micrograms of peginterferon beta-1a in 0.5 mL.
Icelandic: Hver áfylltur lyfjapenni inniheldur 125 míkrógrömm af peginterferóni beta-1a í 0,5 ml.
English: Plegridy is for subcutaneous use.
Icelandic: Plegridy er ætlað til inndælingar undir húð.
English: Pack sizes: - The Plegridy Initiation Pack contains one orange pre-filled syringe of 63 micrograms and one blue pre-filled syringe of 94 micrograms.
Icelandic: Plegridy upphafspakkning inniheldur einn áfylltan lyfjapenna merktur appelsínugulur með 63 míkrógrömmum og einn blámerktan áfylltan lyfjapenna með 94 míkrógrömmum.
English: Plegridy 63 micrograms solution for injection in pre-filled syringe Plegridy 94 micrograms solution for injection in pre-filled syringe peginterferon beta-1a
Icelandic: Plegridy 63 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Plegridy 94 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna peginterferón beta-1a
English: Hepatic impairment
Icelandic: - Áverkar á stungustað
English: Step 4: Choose and clean your injection site a. Choose an injection site in your thigh, abdomen, or the back of your upper arm (see highlighted areas in Figure D).
Icelandic: Veldu stungustað á lærinu, kviðnum eða á aftanverðum upphandlegg (sjá lituð svæði á mynd D).
English: Solution for injection 2 pre-filled pens
Icelandic: Stungulyf, lausn 2 áfylltir lyfjapennar
English: Plegridy 94 micrograms solution for injection in pre-filled syringe Each pre-filled syringe contains 94 micrograms of peginterferon beta-1a* in 0.5 mL solution for injection.
Icelandic: Plegridy 94 míkrógrömm stungulyf, lausn í áfylltum lyfjapenna Hver áfylltur lyfjapenni inniheldur 94 míkrógrömm af peginterferón beta-1a* í 0,5 ml stungulyfi, lausn.
English: No information is available on the effects of peginterferon beta-1a on male fertility in animals.
Icelandic: Ekkert er vitað um áhrif peginterferóns beta-1a á frjósemi karldýra.
English: Accordingly, the half-life (t1/2) of peginterferon beta-1a is approximately 2-fold longer than non-pegylated interferon beta-1a in healthy volunteers.
Icelandic: 2-falt lengri en ópegýleraðs interferón beta-1a hjá heilbrigðum sjálfboðaliðum.
English: Instructions for injecting Plegridy pre-filled syringe BEFORE YOU START How to inject Plegridy
Icelandic: Upplýsingar um Plegridy og við hverju það er notað Áður en byrjað er að nota Plegridy Hvernig nota á Plegridy
English: 1 pre-filled syringe contains 94 micrograms of peginterferon beta-1a in 0.5 mL.
Icelandic: 1 áfylltur lyfjapenni inniheldur 94 míkrógrömm af peginterferóni beta-1a í 0,5 ml.
English: This could lock the pen
Icelandic: Þá gæti lyfjapenninn læst sér.
English: 1 pre-filled syringe contains 63 micrograms of peginterferon beta-1a in 0.5 mL.
Icelandic: 1 áfylltur lyfjapenni inniheldur 63 míkrógrömm af peginterferóni beta-1a í 0,5 ml.
English: Plegridy pre-filled syringe must not be used if the liquid is coloured, cloudy, or contains floating particles.
Icelandic: Ekki nota Plegridy áfyllta sprautu ef vökvinn er litaður, skýjaður eða inniheldur fljótandi agnir.
English: Subcutaneous use
Icelandic: Förgun notaðrar
English: Each pre-filled pen contains 125 micrograms of peginterferon beta-1a in 0.5 mL.
Icelandic: Hver áfyllt sprauta inniheldur 125 míkrógrömm af peginterferóni beta-1a í 0,5 ml.
English: Which dose
Icelandic: Hvaða skammtur
English: Flu-like symptoms
Icelandic: Sjúklingar sem fengu
English: Plegridy 125 micrograms solution for injection in pre-filled syringe peginterferon beta-1a
Icelandic: Plegridy 125 míkrógrömm stungulyf, lausn í áfylltri sprautu peginterferón beta-1a
English: Do not use more than one pre-filled syringe per 14-day period (every 2 weeks).
Icelandic: Notaðu ekki meira en eina áfyllta sprautu á 14 daga tímabili (á 2 vikna fresti).