FrancophonIA/ELRC3.0 huggingface dataset:
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu.
Slovenian: Podrobne informacije o tem zdravilu so dostopne na spletni strani Evropske agencije za zdravila EMA http://www.ema.europa.eu.
English: • Increased urine output
Slovenian: • Povečano izločanje urina
English: Do not use this medicine if you notice particles or a discolouration.
Slovenian: Zdravila ne uporabljajte, če opazite kakršne koli delce ali če je raztopina motna.
English: • Loss of appetite
Slovenian: • Izguba apetita
English: Please tell your doctor or hospital pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Slovenian: Povejte svojemu zdravniku ali bolnišničnemu farmacevtu, če jemljete ali ste pred kratkim jemali katero koli zdravilo, tudi če ste ga dobili brez recepta.
English: Randomised and treated patients Fully supplemented patients
Slovenian: Bolniki s popolnim bolniki dopolnjevanjem
English: Concomitant use not recommended: Live attenuated vaccines (except yellow fever, for which concomitant use is contraindicated): Risk of systemic, possibly fatal, disease.
Slovenian: Odsvetovana sočasna uporaba: Živa oslabljena cepiva (razen proti rumeni mrzlici, za katero je sočasna uporaba kontraindicirana): tveganje za sistemsko, potencialno smrtno bolezen.
English: Clinical efficacy
Slovenian: Klinična učinkovitost:
English: There are no data from the use of pemetrexed in pregnant women; but pemetrexed, like other antimetabolites, is suspected to cause serious birth defects when administered during pregnancy.
Slovenian: Podatkov o uporabi pemetrekseda pri nosečnicah ni, a za pemetreksed, kot za druge anti-metabolite, sumimo, da povzroča resne prirojene okvare, če ga dajemo med nosečnostjo.
English: Calculate the dose and the number of Pemetrexed Sandoz vials needed.
Slovenian: Izračunajte odmerek in število potrebnih vial zdravila Pemetreksed Sandoz.
English: • Upset stomach
Slovenian: •Razdražen želodec
English: Creatinine clearance should be ≥ 45 ml/min.
Slovenian: Očistek kreatinina mora biti  45 ml/min.
English: If you are also receiving cisplatin, your doctor will make sure that you are properly hydrated and receive appropriate treatment before and after receiving cisplatin to prevent vomiting.
Slovenian: Če prejemate tudi cisplatin, bo vaš zdravnik pred prejemanjem cisplatina in po njem preveril, ali ste ustrezno hidrirani ter da prejemate ustrezno zdravljenje za preprečevanje bruhanja.
English: • Low white blood cells
Slovenian: • Nizko število belih krvnih celic
English: 75% of previous dose
Slovenian: 75% predhodnega odmerka
English: Patients must also receive an intramuscular injection of vitamin B12 (1,000 micrograms) in the week preceding the first dose of pemetrexed and once every three cycles thereafter.
Slovenian: Bolniki morajo prejeti tudi intramuskularno injekcijo vitamina B12 (1000 mikrogramov) v tednu pred prvim odmerkom pemetrekseda in enkrat vsake tri cikluse zatem.
English: • Pancytopenia- combined low counts of white cells, red cells and platelets
Slovenian: • Pancitopenija - skupno nizko število belih krvnih celic, rdečih krvnih celic in trombocitov
English: Pharmacotherapeutic group: Antineoplastic agents, folic acid analogues, ATC code: L01BA04
Slovenian: Farmakoterapevtska skupina: Zdravila z delovanjem na novotvorbe, analogi folne kisline, Oznaka ATC: L01BA04
English: Your doctor will discuss with you the potential risk of taking Pemetrexed Sandoz during pregnancy.
Slovenian: S svojim zdravnikom se pogovorite o možnem tveganju pri prejemanju zdravila Pemetreksed Sandoz v času nosečnosti.
English: Before each infusion you will have samples of your blood taken to evaluate if you have sufficient kidney and liver function and to check that you have enough blood cells to receive Pemetrexed Sandoz.
Slovenian: Pred vsako infuzijo vam bodo odvzeli vzorce krvi za vrednotenje delovanja vaših ledvic in jeter ter oceno, ali imate dovolj krvnih celic za prejemanje zdravila Pemetreksed Sandoz.
English: Alkaline phosphatase (AP), aspartate aminotransferase (AST or SGOT), and alanine aminotransferase (ALT or SGPT) should be ≤ 3 times upper limit of normal.
Slovenian: Alkalna fosfataza (AF), aspartatna aminotransferaza (AST ali SGOT) in alaninska aminotransferaza (ALT ali SGPT) morajo biti  3-kratnik zgornje meje normalnih vrednosti.
English: **In the pemetrexed/cisplatin arm, randomised and treated (N=225) and fully supplemented (N=167).
Slovenian: **V veji zdravljenja s pemetreksedom /cisplatinom, randomizirani in zdravljeni (N = 225) ter s popolnim dopolnjevanjem (N = 167).
English: Patients should be regularly monitored for acute tubular necrosis, decreased renal function and signs and symptoms of nephrogenic diabetes insipidus (e.g. hypernatraemia).
Slovenian: Bolnike je treba redno spremljati zaradi akutne tubulne nekroze, zmanjšane ledvične funkcije ter znakov in simptomov nefrogenega diabetesa insipidus (npr. hipernatriemija).
English: • Radiation recall (a skin rash like severe sunburn) which can occur on skin that has previously been exposed to radiotherapy, from days to years after the radiation.
Slovenian: • Radiacijski izpuščaj (kožni izpuščaj kot pri hudi sončni opeklini), ki se lahko pojavi na koži, ki je bila v preteklosti izpostavljena obsevanju, in sicer od nekaj dni do več let po obsevanju.
English: A total of 213 patients (48.3%) completed ≥ 6 cycles and a total of 103 patients (23.4%) completed ≥ 10 cycles of treatment with pemetrexed.
Slovenian: Skupno 213 bolnikov (48,3 %) je zaključilo ≥ 6 ciklov in skupno 103 bolniki (23,4 %) so zaključili ≥ 10 ciklov zdravljenja s pemetreksedom
English: Very common Creatinine clearance decreased**
Slovenian: Znižan očistek kreatinina**
English: 50% of previous dose
Slovenian: 50% predhodnega odmerka
English: Concomitant use contraindicated: Yellow fever vaccine: Risk of fatal generalised vaccinale disease (see section 4.3).
Slovenian: Kontraindicirana sočasna uporaba: Cepivo proti rumeni mrzlici: tveganje za smrtno generalizirano bolezen po cepljenju (glejte poglavje 4.3).
English: Patients must receive adequate antiemetic treatment and appropriate hydration prior to and/or after receiving cisplatin (see also cisplatin Summary of Product Characteristics for specific dosing advice).
Slovenian: Bolniki morajo prejeti zadostno antiemetično zdravljenje, pred in/ali po prejemanju cisplatina jih moramo tudi ustrezno hidrirati (glejte tudi Povzetek glavnih značilnosti zdravila cisplatina za posebne nasvete o odmerjanju).
English: Upon recovery, patients should be re-treated using the guidelines in Tables 1, 2, and 3, which are applicable for Pemetrexed Sandoz used as a single agent or in combination with cisplatin.
Slovenian: Po okrevanju bolnike ponovno zdravimo z uporabo smernic v Preglednicah 1, 2 in 3, ki veljajo za zdravilo Pemetreksed Sandoz, če jo uporabljamo kot edino učinkovino ali v kombinaciji s cisplatinom.
English: Pemetrexed is mainly eliminated unchanged renally by tubular secretion and to a lesser extent by glomerular filtration.
Slovenian: Pemetreksed se izloča predvsem nespremenjen preko ledvic s tubulno sekrecijo in v manjšem obsegu z glomerulno filtracijo.
English: Driving and using machines Pemetrexed Sandoz may make you feel tired.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Zdravilo Pemetreksed Sandoz lahko povzroči, da se boste počutili utrujene.
English: In clinical studies, patients with creatinine clearance of ≥ 45 ml/min required no dose adjustments other than those recommended for all patients.
Slovenian: V kliničnih študijah bolniki z očistkom kreatinina  45 ml/min niso potrebovali prilagajanja odmerkov, razen tistih prilagoditev, ki jih priporočamo za vse bolnike.
English: a Statistically significant for non-inferiority, with the entire confidence interval for HR well below the 1.17645 non-inferiority margin (p < 0.001).
Slovenian: aStatistično pomembna za prednost, s celotnim intervalom zaupanja za RT znatno pod 1,17645 mejoprednosti (p < 0,001).
English: Kaplan-Meier plots of overall survival by histology
Slovenian: Kaplan Meier-jeva grafa skupnega preživetja glede na histologijo
English: Children and adolescents There is no relevant use of Pemetrexed Sandoz in the paediatric population.
Slovenian: Otroci in mladostniki Zdravilo Pemetreksed Sandoz ni primerno za uporabo pri pediatrični populaciji.
English: 28023 (Aravaca) Madrid España
Slovenian: Osa Mayor, nº 4 28023 (Aravaca) Madrid España
English: • Hypernatraemia - increased sodium in blood
Slovenian: • Hipernatriemija - zvišane ravni natrija v krvi
English: Men are advised not to father a child during and up to 6 months following treatment with Pemetrexed Sandoz and should therefore use effective contraception during treatment with Pemetrexed Sandoz and for up to 6 months afterwards.
Slovenian: Moškim odsvetujemo, da bi v času zdravljenja z zdravilom Pemetreksed Sandoz ter do 6 mesecev po zdravljenju s tem zdravilom spočeli otroka, zato naj v času zdravljenja z zdravilom Pemetreksed Sandoz ter do 6 mesecev po zdravljenju s tem zdravilom uporabljajo učinkovito kontracepcijo.
English: Hepatic impairment: No relationships between AST (SGOT), ALT (SGPT), or total bilirubin and pemetrexed pharmacokinetics were identified.
Slovenian: Bolniki z okvarjenim delovanjem jeter: Ugotovili niso nobenih razmerij med AST (SGOT), ALT (SGPT), ali celokupnim bilirubinom in farmakokinetiko pemetrekseda.
English: Pemetrexed + Cisplatin Gemcitabine + Cisplatin
Slovenian: Pemetreksed + Cisplatin Gemcitabin + Cisplatin
English: Treatment with Pemetrexed Sandoz should be discontinued if a patient experiences any haematologic or non-haematologic Grade 3 or 4 toxicity after 2 dose reductions or immediately if Grade 3 or 4 neurotoxicity is observed.
Slovenian: Zdravljenje z zdravilom Pemetreksed Sandoz moramo prekiniti, če bolnik izkusi kakršnokoli hematološko ali nehematološko toksičnost stopnje 3 ali 4 po 2 znižanjih odmerka ali nemudoma, če opazimo nevrološko toksičnost stopnje 3 ali 4.
English: Pemetrexed total systemic clearance is 91.8 ml/min and the elimination half-life from plasma is 3.5 hours in patients with normal renal function (creatinine clearance of 90ml/min).
Slovenian: Celotni sistemski očistek pemetrekseda je 91,8 ml/min, razpolovni čas izločanja iz plazme je 3,5 ur pri bolnikih z normalnim ledvičnim delovanjem (očistek kreatinina 90 ml/min).
English: • Allergic reaction: skin rash / burning or prickling sensation
Slovenian: • Alergijske reakcije: kožni izpuščaji/pekoč ali zbadajoč občutek
English: A significant increase in the incidence of possibly study-drug-related Grade 3/4 neutropenia was observed with longer exposure to pemetrexed (≤ 6 cycles: 3.3 %, > 6 cycles: 6.4 %: p=0.046).
Slovenian: Znatno povečanje pojavnosti nevtropenije stopnje 3/4, ki je lahko povezano s preučevanim zdravilom, so opazili pri dolgotrajnejši izpostavljenosti pemetreksedu (≤ 6 ciklov: 3,3 %, > 6 ciklov: 6,4 %: p=0,046).
English: Pemetrexed Sandoz has minor influence on the ability to drive and use machines as it has been reported that pemetrexed may cause fatigue.
Slovenian: Zdravilo Pemetreksed Sandoz ima blag vpliv na sposobnost vožnje in upravljanja s stroji, saj so poročali, da lahko pemetreksed povzroči utrujenost.
English: • Pain, redness, swelling or sores in your mouth
Slovenian: • Bolečina, rdečina, otekanje ali rane v vaših ustih
English: * Refer to National Cancer Institute CTC version 2 for each grade of toxicity except the term “creatinine clearance decreased”.
Slovenian: *Glejte CTC Nacionalnega inštituta za rakava obolenja, različico 2, za vsako stopnjo toksičnosti, razen izraza “znižan očistek kreatinina”.
English: • Oedema (excess fluid in body tissue, causing swelling)
Slovenian: • Edem (preveč tekočine v telesnih tkivih, kar povzroča oteklino)
English: OTHER SPECIAL WARNING(S), IF NECESSARY
Slovenian: DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA Citotoksično
English: Do not use Pemetrexed Sandoz: - if you are allergic (hypersensitive) to pemetrexed or any of the other ingredients of this medicine (listed in section 6).
Slovenian: Ne uporabljajte zdravila Pemetreksed Sandoz: - če ste alergični na (preobčutljivi za) pemetreksed ali na katero koli sestavino tega zdravila
English: The dose of Pemetrexed Sandoz is 500 milligrams for every square metre of your body's surface area.
Slovenian: Odmerek zdravila Pemetreksed Sandoz je 500 miligramov za vsak kvadratni meter površine vašega telesa.
English: Side effects with Pemetrexed Sandoz may include:
Slovenian: Neželeni učinki z zdravilom Pemetreksed Sandoz lahko vključujejo:
English: Your doctor may decide to change the dose or delay treating you depending on your general condition and if your blood cell counts are too low.
Slovenian: Vaš zdravnik se bo morda odločil spremeniti odmerek ali odložiti zdravljenje, odvisno od vašega splošnega stanja, ter ob prenizkem številu krvnih celic.
English: Infectious and non-infectious disorders of the dermis, the hypodermis and/or the subcutaneous tissue have been reported with an unknown frequency (e.g. acute bacterial dermo-hypodermitis, pseudocellulitis, dermatitis).
Slovenian: Poročali so o infektivnih in neinfektivnih boleznih dermisa, hipodermisa in/ali podkožja z neznano pogostnostjo (na primer akutni bakterijski dermohipodermitis, psevdocelulitis, dermatitis).
English: Sandoz GmbH Biochemiestrasse 10 A-6250 Kundl Austria
Slovenian: Sandoz GmbH Biochemiestrasse 10 A-6250 Kundl Avstrija
English: If you have an accumulation of fluid around your lungs, your doctor may decide to remove the fluid before giving you Pemetrexed Sandoz.
Slovenian: Če se vam okrog pljuč nabira tekočina, se bo vaš zdravnik morda odločil tekočino pred dajanjem zdravila Pemetreksed Sandoz odstraniti.
English: Each pack of Pemetrexed Sandoz consists of one vial with protective plastic overwrap, containing 100 mg, 500 mg or 1000 mg of pemetrexed.
Slovenian: Vsako pakiranje zdravila Pemetreksed Sandoz vsebuje eno vialo z zaščitnim plastičnim ovojem, ki vsebuje 100 mg, 500 mg ali 1000 mg pemetrekseda.
English: The separation between the treatment arms was achieved by improvement in lung function in the pemetrexed/cisplatin arm and deterioration of lung function over time in the control arm.
Slovenian: Razlikovanje med vejama zdravljenja je bilo doseženo z izboljšanjem delovanja pljuč v veji zdravljenja s pemetreksedom/cisplatinom in poslabšanjem pljučnega delovanja s časom v kontrolni veji preskušanja.
English: Contact your doctor if you get a severe rash, or itching, or blistering (Stevens-Johnson Syndrome or Toxic epidermal necrolysis).
Slovenian: Obvestite svojega zdravnika, če se pojavijo hud izpuščaj, srbenje ali mehurčki (Stevens-Johnsonov sindrom ali toksična epidermalna nekroliza).
English: If you have been recently vaccinated, please tell your doctor, as this can possibly cause bad effects with Pemetrexed Sandoz.
Slovenian: Če ste bili nedavno cepljeni, prosimo, povejte to svojemu zdravniku, saj lahko to ob jemanju zdravila Pemetreksed Sandoz povzroča škodljive učinke.
English: • Inflammation of the skin, mainly of the lower limb with swelling, pain and redness
Slovenian: • Vnetje kože, večinoma spodnjih okončin, z otekanjem, bolečino in pordelostjo
English: 75% of previous dose (both pemetrexed and cisplatin)
Slovenian: 75% predhodnega odmerka (obeh pemetrekseda in cisplatina)
English: Most of these events resolved after pemetrexed withdrawal.
Slovenian: Večina teh učinkov je minila po prenehanju zdravljenja s pemetreksedom.
English: Corticosteriods: your doctor will prescribe you steroid tablets (equivalent to 4 milligram of dexamethasone twice a day) that you will need to take on the day before, on the day of, and the day after Pemetrexed Sandoz treatment.
Slovenian: Kortikosteroidi: vaš zdravnik vam bo predpisal tablete steroidov (ustrezno 4 miligramom deksametazona dvakrat dnevno), ki jih boste morali jemati dan pred zdravljenjem z zdravilom Pemetreksed Sandoz, na dan zdravljenja in na dan po zdravljenju z zdravilom Pemetreksed Sandoz.
English: If you currently have or have previously had problems with your kidneys, talk to your doctor or hospital pharmacist as you may not be able to receive Pemetrexed Sandoz.
Slovenian: Če imate ali ste imeli težave z ledvicami, se pogovorite s svojim zdravnikom ali bolnišničnim farmacevtom, ker morda ne boste mogli prejeti zdravila Pemetreksed Sandoz.
English: CTC a Grade
Slovenian: Stopnja CTC a
English: Dose for Cisplatin (mg/m2)
Slovenian: Odmerek cisplatina (mg/m2)
English: Sandoz Farmacéutica, S.A. Centro Empresarial Osa Mayor Avda.
Slovenian: Sandoz Farmacéutica, S.A. Centro Empresarial Osa Mayor
English: The use of Pemetrexed Sandoz should be avoided during pregnancy.
Slovenian: Uporabi zdravila Pemetreksed Sandoz med nosečnostjo se izogibamo.
English: • Blood clots in the lung blood vessels (pulmonary embolism)
Slovenian: • Krvni strdki v krvnih žilah v pljučih (pljučna embolija)
English: Cisplatin is also given by infusion into one of your veins, and is given approximately 30 minutes after the infusion of Pemetrexed Sandoz has finished.
Slovenian: Cisplatin tudi dajemo v obliki infuzije v veno, približno 30 minut po zaključku infuzije zdravila Pemetreksed Sandoz.
English: • Fast heart rate
Slovenian: • Hiter srčni utrip
English: • Conjunctivitis (inflamed eye)
Slovenian: •Konjunktivitis (vnetje očesa)
English: Therefore, the use of pemetrexed in patients with creatinine clearance of < 45ml/min is not recommended (see section 4.2).
Slovenian: Zato uporabe pemetrekseda pri bolnikih z očistkom kreatinina < 45 ml/min ne priporočamo (glejte poglavje 4.2).
English: • Thirst and increased water consumption
Slovenian: • Žeja in povečan vnos tekočin
English: ***Integrated adverse reactions table combines the results of the JMEN pemetrexed maintenance (N=663) and PARAMOUNT continuation pemetrexed maintenance (N=539) studies.
Slovenian: *** Skupna preglednica neželenih učinkov združuje rezultate študij vzdrževalnega zdravljenja samo s pemetreksedom JMEN (N=663) in nadaljevalnega zdravljenja s pemetreksedom (PARAMOUNT: N=539).
English: • Periodic safety update reports
Slovenian: • Periodično poročilo o varnosti zdravila
English: • Immune mediated haemolytic anaemia (antibody-mediated destruction of red blood cells)
Slovenian: • Hemolitična anemija (anemija zaradi propada rdečih krvnih celic)
English: Please tell your doctor if you are taking any medicine for pain or inflammation (swelling), such as medicines called “nonsteroidal anti-inflammatory drugs” (NSAIDs), including medicines purchased without a doctor's prescription (such as ibuprofen).
Slovenian: Druga zdravila in zdravilo Pemetreksed Sandoz Prosimo, povejte svojemu zdravniku, če jemljete zdravila proti bolečinam ali vnetju (oteklinam), denimo zdravila, imenovana “nesteroidna protivnetna zdravila” (NSAID-i), vključno z zdravili, ki ste jih dobili brez recepta (kot denimo ibuprofen).
English: • Taste change
Slovenian: •Sprememba okusa
English: Fisher's exact p-value* < 0.001
Slovenian: Fisherjeva točna p-vrednost*
English: Concomitant administration of substances that are also tubularly secreted (e.g., probenecid, penicillin) could potentially result in delayed clearance of pemetrexed.
Slovenian: Sočasno dajanje snovi, ki se tudi izločajo s tubulno sekrecijo (denimo probenecid, penicilin), lahko potencialno povzroči zakasnjeni očistek pemetrekseda.
English: If patients develop non-haematologic toxicities ≥ Grade 3 (excluding neurotoxicity), Pemetrexed Sandoz should be withheld until resolution to less than or equal to the patient's pre-therapy value.
Slovenian: Če se pri bolnikih razvijejo nehematološke toksičnosti  stopnje 3 (z izjemo nevrološke toksičnosti), moramo dajanje zdravila Pemetreksed Sandoz prekiniti, dokler se vrednosti ne povrnejo na manjše ali enake, kot jih je imel bolnik pred zdravljenjem.
English: Therefore, caution should be made when administering higher doses of NSAIDs or acetylsalicylic acid, concurrently with pemetrexed to patients with normal function (creatinine clearance ≥ 80 ml/min).
Slovenian: Zato je pri dajanju visokih odmerkov NSAID-ov ali acetilsalicilne kisline sočasno s pemetreksedom bolnikom z normalnim delovanjem ledvic (očistek kreatinina  80 ml/min) potrebna previdnost.
English: • Extremity pain, low temperature and discolouration have been reported.
Slovenian: • Poročali so tudi o bolečinah v okončinah, nizki temperaturi in bledosti okončin.
English: • If you experience sudden breathlessness, intense chest pain or cough with bloody sputum (uncommon)(may indicate a blood clot in the blood vessels of the lungs)
Slovenian: Če doživite nenadno težko dihanje, močno bolečino v prsih ali kašelj s krvavim izmečkom (redko) (lahko kaže na krvni strdek v krvnih žilah v pljučih).
English: Patients must take oral folic acid or a multivitamin containing folic acid (350 to 1,000 micrograms) on a daily basis.
Slovenian: Bolniki morajo dnevno jemati peroralno folno kislino ali multivitaminski pripravek, ki jo vsebuje (350 do 1000 mikrogramov).
English: A hospital pharmacist, nurse or doctor will have mixed the Pemetrexed Sandoz powder with 9 mg/ml (0.9 %) sodium chloride solution for injection before it is given to you.
Slovenian: Bolnišnični farmacevt, medicinska sestra ali zdravnik bo prašek Pemetreksed Sandoz, preden ga boste prejeli, zmešal z 9 mg/ml (0,9 %) raztopino natrijevega klorida za injiciranje.
English: You will always receive Pemetrexed Sandoz by infusion into one of your veins.
Slovenian: Zdravilo Pemetreksed Sandoz boste vedno prejeli v obliki infuzije v veno.
English: Clinically relevant Grade 3 and Grade 4 laboratory toxicities were similar between integrated Phase 2 results from three single-agent pemetrexed studies (N = 164) and the Phase 3 single-agent pemetrexed study described above, with the exception of neutropenia (12.8 % versus 5.3 %, respectively) and alanine aminotransferase elevation (15.2 % versus 1.9 %, respectively).
Slovenian: Klinično pomembne laboratorijske toksičnosti stopenj 3 in 4 so bile podobne pri integriranih rezultatih faze 2 treh študij pemetrekseda kot edine učinkovine (n = 164) in faze 3 študije pemetrekseda kot edine učinkovine, opisane zgoraj, z izjemo nevtropenije (12,8 % oziroma 5,3 %) in povišanja alaninske aminotransferaze (15,2 % oziroma 1,9 %).
English: Abbreviations: CI = confidence interval; HR = hazard ratio; ITT = intent-to-treat; N = total population size.
Slovenian: Okrajšave: IZ = interval zaupanja; RT = razmerje tveganja; NZ = namen zdraviti; N =velikost populacije.
English: Limited clinical data from a separate randomised, Phase 3, controlled trial, suggest that efficacy data (overall survival, progression-free survival) for pemetrexed are similar between patients previously pre-treated with docetaxel (N = 41) and patients who did not receive previous docetaxel treatment (N = 540).
Slovenian: Omejeni klinični podatki iz ločeno randomiziranih, kontroliranih preskušanj faze 3, nakazujejo, da so podatki o učinkovitosti (skupno preživetje, preživetje brez napredovanja) za pemetreksed podobni med bolniki, ki so bili predhodno zdravljeni z doksatakselom (N = 41) in bolniki, ki niso prejeli predhodnega zdravljenja z doksatakselom (N = 540).
English: Pemetrexed Sandoz is a medicine used in the treatment of cancer.
Slovenian: Pemetreksed Sandoz je zdravilo, ki ga uporabljamo pri zdravljenju raka.
English: • Dehydration
Slovenian: • Dehidracija
English: • Hepatitis (inflammation of the liver) • Anaphylactic shock (severe allergic reaction)
Slovenian: • Anafilaktični šok (huda alergična reakcija)
English: • Bullous conditions (blistering skin diseases)-including Stevens-Johnson syndrome and Toxic epidermal necrolysis
Slovenian: • Bulozna stanja (bolezni s kožnimi mehurji), vključno s Stevens-Johnsonovim sindromom in toksično epidermalno nekrolizo