FrancophonIA/ELRC3.0 huggingface dataset:
English: In adults who had not been treated before, Rebetol in combination with interferon alfa 2b was more effective than interferon alfa 2b on its own, with 41% of the patients responding to the combination treatment and 16% to the interferon alone.
Croatian: Kod bolesnika koji nisu prethodno liječeni Rebetol u kombinaciji s interferonom alfa 2b bio je učinkovitiji nego sam interferon alfa 2b; 41 % pacijenata reagiralo je na kombiniranu terapiju, a 16 % reagiralo je na sam interferon.
English: Response rates were higher when Rebetol was used with peginterferon alfa 2b.
Croatian: Stope odgovora bile su više kada se Rebetol primjenjivao s peginterferonom alfa 2b.
English: What benefit has Rebetol shown during the studies?
Croatian: Koje su koristi lijeka Rebetol utvrđene u ispitivanjima?
English: Rebetol is used in combination with other medicines to treat adults with long-term hepatitis C (a disease of the liver due to infection with the hepatitis C virus).
Croatian: Rebetol je u kombinaciji s drugim lijekovima indiciran za liječenje kroničnog hepatitisa C (bolesti jetre nastale uslijed infekcije virusom hepatitisa C) u odraslih osoba.
English: In all of the studies, Rebetol was given in combination with interferon alfa-2b or peginterferon alfa-2b.
Croatian: Rebetol je u svim ispitivanjima davan u kombinaciji s interferonom alfa-2b ili peginterferonom alfa-2b.
English: Two main studies involving 1,503 adult patients with type 1 hepatitis C and compensated liver disease investigated the effect of ribavirin in a triple therapy combination with peginterferon alfa-2b and boceprevir.
Croatian: U dvama glavnim ispitivanjima, koja su obuhvaćala 1503 odrasla bolesnika s hepatitisom C tipa 1 i kompenziranom bolesti jetre, ispitivao se učinak ribavirina u trostrukoj kombiniranoj terapiji s peginterferonom alfa-2b i boceprevirom.
English: Rebetol in combination with peginterferon alfa 2b was also effective in adults with cirrhosis or HIV.
Croatian: Kombinirana terapija lijeka Rebetol i peginterferona alfa 2b također je bila učinkovita kod odraslih bolesnika s cirozom ili virusom HIV-a.
English: The Committee noted that Rebetol in combination with other medicines, including peginterferon alfa and DAAs is effective against long-term hepatitis C virus infection in adults and children.
Croatian: Odbor je uočio da je Rebetol u kombinaciji s drugim lijekovima, uključujući peginterferon alfa i antivirotike koji djeluju direktno, učinkovit protiv kronične infekcije virusom hepatitisa C u odraslih i u djece.
English: In the studies on triple therapy in patients with type 1 hepatitis C and compensated liver disease, ribavirin in combination with peginterferon alfa 2b and boceprevir was shown to be more effective than the dual combination with peginterferon alfa 2b alone.
Croatian: U ispitivanjima trostruke terapije u bolesnika s hepatitisom C tipa 1 i kompenziranom bolesti jetre pokazalo se da je ribavirin u kombinaciji s peginterferonom alfa 2b i boceprevirom učinkovitiji nego dvostruka kombinacija samo s peginterferonom alfa 2b.
English: What is Rebetol used for?
Croatian: Za što se Rebetol koristi?
English: A 40% increase was seen among patients who had been treated before.
Croatian: U bolesnika koji su prethodno bili liječeni uočeno je 40 %-tno povećanje.
English: How is Rebetol used?
Croatian: Kako se Rebetol koristi?
English: For a full list of restrictions, see the package leaflet.
Croatian: Potpuni popis ograničenja potražite u uputi o lijeku.
English: How does Rebetol work?
Croatian: Kako djeluje Rebetol?
English: For the full list of side effects reported with Rebetol, see the package leaflet.
Croatian: Potpuni popis nuspojava zabilježenih pri primjeni lijeka Rebetol potražite u uputi lijeka.
English: How has Rebetol been studied?
Croatian: Kako je Rebetol ispitivan?
English: Wash hands after use.
Croatian: Nakon upotrebe oprati ruke.
English: These signs are temporary and should resolve when the journey ends.
Croatian: Ovi znakovi su privremeni te bi trebali proći kada putovanje završi.
English: EXP {month/year} Once broached, use by:………..
Croatian: ROK VALJANOSTI EXP {mjesec/godina} Jednom odčepljen, upotrijebiti do:….
English: The inter-individual variation in kinetics may be large, up to 70 CV% for AUC.
Croatian: Inter-individualne razlike u kinetici mogu biti velike, čak do 70 CV% za AUC.
English: Date of first authorisation: 29/09/2006.
Croatian: Datum prvog odobrenja: 29/09/2006
English: Date of last renewal: 29/09/2011.
Croatian: Datum posljednjeg produljenja: 29/09/2011
English: * Correct dose for dogs of less than 3 kg cannot be accurately achieved.
Croatian: *Točna doza za pse lakše od 3 kg ne može se točno postići
English: Vall de Bianya 17813 (Girona) SPAIN
Croatian: Vall de Bianya 17813 (Girona) ŠPANJOLSKA
English: • Holding one side of the cut firmly, pull the other side towards the centre of the blister until the tablet is visible.
Croatian: • Držeći čvrsto jednu stranu zareza povucite drugu stranu prema sredini blistera dok se ne vidi tableta.
English: Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Croatian: Rok valjanosti veterinarsko-medicinskog proizvoda kada je zapakiran za prodaju: 3 godine.
English: No data have been presented on overdoses in adult cats.
Croatian: Nema podataka o predoziranju u odraslih mačaka.
English: EXP {month/year} Once broached, use within 28 days.
Croatian: Jednom otvoren, upotrijebiti unutar 28 dana.
English: Vomiting is a complex process coordinated centrally by the emetic centre.
Croatian: Povraćanje je složen proces koji je centralno koordiniran od strane centra za povraćanje.
English: The elimination t1/2 following intravenous dosing was approximately 5.8 h.
Croatian: Eliminacija t1/2 nakon intravenoznog doziranja je oko 5,8 h.
English: Shelf life of half tablets: 2 days.
Croatian: Rok valjanosti prepolovljene tablete: 2 dana.
English: For the major metabolite 10.4% of the maropitant dose was recovered in urine and 9.3% in faeces.
Croatian: Za glavni metabolit 10,4% doze maropitanta je utvrđeno u urinu i 9,3% u fecesu.
English: Sulphobutyl ether β-cyclodextrin (SBECD) Metacresol
Croatian: Sulfobutil eter β-ciklodekstrin (SBECD) Metakrezol
English: 4 tablets
Croatian: 4 tablete
English: Although Cerenia has been demonstrated to be effective in both the treatment and prevention of emesis induced by chemotherapy, it was found more efficacious if used preventively.
Croatian: Iako je Cerenia pokazala učinkovitost i kod liječenja i sprječavanja povraćanja uzrokovanog kemoterapijom, smatra se da je učinkovitije ako se daje preventivno.
English: Each cardboard box contains 1 vial.
Croatian: Svaka kartonska kutija sadrži 1 bočicu.
English: This centre consists of several brainstem nuclei (area postrema, nucleus tractus solitarius, dorsal motor nucleus of the vagus) that receive and integrate sensory stimuli from central and peripheral sources and chemical stimuli from the circulation and the cerebro-spinal fluid.
Croatian: Centar se sastoji od nekoliko jezgri moždanog stabla (area postrema, nucleus tractus solitarius, dorzalna motorička jezgra vagusa) koje primaju i integriraju osjetne podražaje iz centralnih i perifernih izvora i kemijske podražaje iz cirkulacije i cerebro-spinalne tekućine.
English: Cerenia must not be mixed with other veterinary medicinal products in the same syringe as its compatibility with other products has not been tested.
Croatian: Cerenia se ne smije miješati u istoj brizgalici s drugim veterinarsko medicinskim proizvodima zato što kompatibilnost s drugim proizvodima nije testirana.
English: Cardboard box containing one aluminium-aluminium blister pack, each containing four tablets per pack.
Croatian: Kartonska kutija u kojoj je jedan aluminijsko-aluminijski blister, svaki blister sadrži četiri tablete.
English: Tablets should be administered at least one hour before starting the journey.
Croatian: Tablete treba dati barem jedan sat prije početka putovanja.
English: • For the prevention of perioperative nausea and vomiting and improvement in recovery from general anaesthesia after use of the μ-opiate receptor agonist morphine.
Croatian: • Za sprječavanje perioperativne mučnine, povraćanja i poboljšanje oporavka od opće anestezije nakon primjene agonista µ-opijata receptora, morfija.
English: Note: No attempt should be made to remove the tablet by pushing it through the blister backing as this will damage both the tablet and blister.
Croatian: Napomena: ne pokušavajte izvaditi tabletu gurajući ju kroz blister jer će to oštetiti i tabletu i blister.
English: Overdose (symptoms, emergency procedures, antidotes):
Croatian: Predoziranje (simptomi, postupci u slučaju nužde, antidota):
English: With the extended use of Cerenia tablets in dogs from 5 to 14 consecutive days, the periodic safety update report (PSUR) cycle for Cerenia has been reset and the data lock point for the next PSUR is 30 June 2014 for submission of 6 monthly reports (covering all authorised presentations of the product) for the next two years, followed by yearly reports for the subsequent two years and thereafter at 3 yearly intervals.
Croatian: S produženom uporabom Cerenia tableta u pasa od 5 - 14 uzastopnih dana, ciklus periodičkog izvješća o neškodljivosti (PSUR) je ponovo pokrenut, a zaključavanje baze podataka za sljedeće PSUR-ove je 30. lipanj 2014., za podnošenje 6 mjesečnih izvješća (koja uključuju sva odobrena pakovanja proizvoda) u sljedeće 2 godine, koje potom slijede godišnja izvješća u sljedeće dvije godine, a nakon toga u trogodišnjem intervalu.
English: The elimination halflife at 8 mg/kg was 5.47 hours.
Croatian: Vrijeme polueliminacije pri dozi od 8 mg/kg iznosi 5,47 sati.
English: As the pharmacokinetic variation is large and maropitant accumulates in the body after once daily repeated administration, lower doses than recommended might be sufficient in some individuals and when repeating the dose.
Croatian: S obzirom da je farmakokinetička varijacija velika i da se maropitant nakuplja u organizmu nakon ponovljene dnevne doze, doza niža od preporučene može biti dovoljna kod nekih jedinki u slučaju da je potrebno ponoviti dozu.
English: Treatment may be repeated for up to five consecutive days.
Croatian: Liječenje se može ponoviti do pet uzastopnih dana.
English: Maropitant undergoes cytochrome P450 (CYP) metabolism in the liver.
Croatian: Maropitant prolazi kroz metabolizam citokroma P450 (CYP) u jetri.
English: Croscarmellose sodium Lactose monohydrate Magnesium stearate Microcrystalline cellulose Sunset Yellow (E110) as a colorant
Croatian: Karmelozanatrij Laktoza monohidrat Magnezijev stearat Mikrokristalinična celuloza Sunset žuto (E110) kao bojilo
English: Maropitant (as maropitant citrate monohydrate)
Croatian: Maropitant (u obliku maropitant citrat monohidrata)
English: The safety of maropitant during treatment beyond 5 days has not been explored in the target population (i.e. young dogs suffering from viral enteritis).
Croatian: Neškodljivost maropitanta tijekom liječenja više od 5 dana nije bila istražena u ciljnoj populaciji (tj. u mladih pasa koji boluju od virusnog enteritisa).
English: Pale orange tablet
Croatian: Blijedo narančasta tableta
English: If you notice any side effects, even those not already listed in this package leaflet or you think that the medicine has not worked, please inform your veterinary surgeon.
Croatian: Ako zamijetite bilo koju ozbiljnu nuspojavu ili druge nuspojave koje nisu opisane u uputi o VMP ili mislite da lijek ne djeluje, molimo obavijestite svog veterinara.
English: In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products in the same syringe.
Croatian: U nedostatku ispitivanja kompatibilnosti ovaj veterinarsko-medicinski proizvod ne smije se miješati s drugim veterinarsko-medicinskim proizvodima.
English: In the case of accidental eye exposure, flush the eyes with plenty of water and seek medical attention.
Croatian: U slučaju nehotičnog kontakta s očima, isprati s puno vode i potražiti liječničku pomoć.
English: Administering Cerenia on a completely empty stomach may cause your dog to vomit.
Croatian: Davanje Cerenie na prazan želudac može uzrokovati povraćanje kod Vašeg psa.
English: Estimates for the oral bioavailability of maropitant were 23.7% at 2 mg/kg and 37.0% at 8 mg/kg.
Croatian: Procjene peroralne bioraspoloživosti maropitanta su bile 23,7% za dozu od 2 mg/kg i 37% za 8 mg/kg.
English: Plasma protein binding of maropitant in dogs is more than 99%.
Croatian: Vezanje proteina plazme za maropitant kod pasa je veće od 99%.
English: Intravenous administration of Cerenia should be given as a single bolus without mixing the product with any other fluids.
Croatian: Intravenoznu primjenu Cerenie treba primijeniti kao jednostruki bolus, bez miješanja proizvoda s drugim tekućinama.
English: Substance P is found in significant concentrations in the nuclei comprising the emetic centre and is considered the key neurotransmitter involved in vomiting.
Croatian: P tvar se u značajnim koncentracijama nalazi u jezgrama koje obuhvaćaju centar povraćanja i smatra se ključnim neurotransmiterom uključenim u akt povraćanja.
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS BLISTER / Tablets
Croatian: OSNOVNI PODACI KOJI SE MORAJU NALAZITI NA BLISTERIMA ILI TRAKAMA BLISTER / Tableta
English: Half-tablets should be stored for a maximum of two days after removal from the blister.
Croatian: Polovinu tablete treba iskoristiti nakon najviše dva dana od otvaranja blistera.
English: At a dose of 8 mg/kg, Cmax of 776 ng/ml was reached at 1.7 hours post-dosing.
Croatian: Pri dozi od 8 mg/kg, postignuta je Cmax od 776 ng/ml, 1,7 sati nakon aplikacije.
English: EU/2/06/062/001 (16 mg tablets) EU/2/06/062/002 (24 mg tablets) EU/2/06/062/003 (60 mg tablets) EU/2/06/062/004 (160 mg tablets)
Croatian: EU/2/06/062/001 (tablete 16 mg) EU/2/06/062/002 (tablete 24 mg) EU/2/06/062/003 (tablete 60 mg) EU/2/06/062/004 (tablete 160 mg)
English: Interaction with other medicinal products and other forms of interaction: Cerenia should not be used concomitantly with Ca-channel antagonists as maropitant has affinity to Ca-channels.
Croatian: Interakcije s drugim medicinskim proizvodima i drugi oblici interakcija: Cerenia se ne smije davati istodobno s antagonistima kalcijevih kanala jer maropitant ima sklonost prema njima.
English: DATE ON WHICH PACKAGE LEAFLET WAS LAST APPROVED
Croatian: 14. DATUM KADA JE UPUTA O VMP ZADNJI PUTA ODOBRENA
English: • Firstly, fold or cut along the perforation between each tablet as shown by the scissor symbol 
Croatian: • Prvo presavinite ili prerežite blister po perforaciji između dvije tablete kako je prikazano simbolom škara .
English: A clear, colourless to light yellow solution.
Croatian: Bistra, bezbojna do blijedo žuta otopina.
English: Injecting the product at refrigerated temperature may reduce pain at injection.
Croatian: Injiciranje rashlađenog pripravka može smanjiti bol prilikom aplikacije.
English: The elimination t1/2 following intravenous dosing was approximately 4.9 h. There appears to be an age-related effect on the pharmacokinetics of maropitant in cats with kittens having higher clearance than adults.
Croatian: Eliminacija t1/2 nakon intravenoznog doziranja je oko 4,9 h.Pretpostavlja se da postoji farmakokinetički efekt maropitanta vezan za starost životinje jer mačići imaju veće izlučivanje od odraslih mačaka
English: For subcutaneous or intravenous use in dogs and cats.
Croatian: Za subkutanu ili intravenoznu primjenu kod pasa i mačaka.
English: Cerenia solution for injection may be administered for up to five days and Cerenia tablets for up to fourteen days.
Croatian: Cerenia otopina za injekciju može se primjenjivati do 5 dana, a Cerenia tablete do četrnaest dana.
English: Therefore, it is recommended to administer the antiemetic prior to administration of the chemotherapeutic agent.
Croatian: S toga se preporučuje davanje antiemetika prije davanja kemoterapeutika.
English: It also contains metacresol (as preservative).
Croatian: Sadrži metakrezol (kao konzervans).
English: In some individual dogs and when repeating the treatment, lower doses than recommended might be sufficient.
Croatian: Kod nekih pasa pri ponovljenom davanju tablete niže doze od propisanih mogu biti dovoljne.
English: Use only according to the benefit-risk assessment by the responsible veterinarian, because conclusive reproductive toxicity studies have not been conducted in any animal species.
Croatian: Primijeniti samo nakon procjene odnosa koristi/rizika od strane odgovornog veterinara, pošto zaključna ispitivanja reproduktivne toksičnosti nisu provedena ni kod jedne od ciljnih vrsta.
English: Dogs should be carefully observed following administration to ensure that each tablet is swallowed.
Croatian: Pse treba motriti nakon davanja lijeka kako bi bili sigurni da je tableta progutana.
English: In very rare cases, anaphylactic type reactions (allergic oedema, urticaria, erythema, collapse, dyspnoea, pale mucous membranes) may occur.
Croatian: U vrlo rijetkim slučajevima mogu se javiti reakcije anafilaktičkog tipa (alergijski edem, urtikarije, eritema, kolaps, dispnea, blijede mukozne sluznice).
English: In case treatment for a longer period than 5 days is regarded as necessary, careful monitoring of potential adverse events should be implemented.
Croatian: U slučaju liječenja u razdoblju dužem od 5 dana potrebno je pažljivo praćenje mogućih nuspojava.
English: 29 route des Industries 37530 Pocé-sur-Cisse FRANCE
Croatian: 37530 Pocé-sur-Cisse
English: Vomiting can be associated with serious, severely debilitating conditions and the cause should be investigated.
Croatian: Povraćanje može biti povezano s teškim i ozbiljnim stanjima, te zbog toga uzroci moraju biti istraženi.
English: Do not use this veterinary medicinal product after the expiry date which is stated on the label of the vial after EXP.
Croatian: Ne koristite veterinarsko-medicinski proizvod poslije isteka roka valjanosti naznačenog na etiketi poslije EXP.
English: CYP2D15 and CYP3A12 were identified as the canine isoforms involved in the hepatic biotransformation of maropitant.
Croatian: CYP2D15 i CYP3A12 su identificirani kao pseći izoformi uključeni u jetrenu biotransformaciju maropitanta.
English: The anti-emetic efficacy of maropitant against central and peripheral emetics was demonstrated in experimental studies including apomorphine, cisplatin and syrup of ipecac (dogs) and xylazine (cats).
Croatian: Antiemetička djelotvornost maropitanta protiv centralnih i perifernih emetika dokazana je u eksperimentalnim ispitivanjima uključujući amorfin, cispaltin i sirup ipekaka (pas) i ksilazin (mačka).
English: Cerenia tablets are available in 16 mg, 24 mg, 60 mg and 160 mg strength.
Croatian: Cerenia tablete su dostupne u jakosti od 16 mg, 24 mg, 60 mg i 160 mg.
English: • For the treatment of vomiting, in combination with other supportive measures.
Croatian: • Za liječenje povraćanja, u kombinaciji s drugim potpornim mjerama.
English: To remove a tablet from the blister the following sequence should be carried out;
Croatian: Da bi se tableta izvadila iz blistera pratite slijedeće korake:
English: Maropitant displays non-linear pharmacokinetics (AUC increases more than proportionally with increasing dose) when administered orally within the 1-16 mg/kg dose range.
Croatian: Maropitant pokazuje nelinearnu farmakokinetiku (povećanje AUC je više nego proporcionalno s povećanjem doze) kada se daje peroralno unutar granica doze od 1-16 mg/kg.
English: By inhibiting the binding of substance P within the emetic centre, maropitant is effective against neural and humoral (central and peripheral) causes of vomiting.
Croatian: Inhibicijom vezanja P tvari u centru za povraćanje, maropitant postaje djelotvoran protiv nervnih i humoralnih (centralnih i perifernih) uzroka povraćanja.
English: • For the prevention and treatment of vomiting, in conjunction with Cerenia solution for injection and in combination with other supportive measures.
Croatian: • Za sprječavanje i liječenje povraćanja uz potpornu terapiju Cerenia otopinom za injekcije i u kombinaciji s drugim potpornim mjerama.
English: Cerenia is not a sedative and some motion sick dogs may show nausea-like signs during travel such as salivation and lethargy.
Croatian: Cerenia nije sedativ i neki psi koji pate od bolesti putovanja mogu pokazati znakove slične mučnini kao na primjer pojačano slinjenje i letargiju.
English: Manufacturer responsible for batch release: FAREVA AMBOISE Zone Industrielle,
Croatian: Proizvođač odgovoran za puštanje serije u promet: FAREVA AMBOISE
English: Maropitant is non-sedative and should not be used as a sedative in motion sickness.
Croatian: Maropitant nema sedirajući učinak i ne treba ga koristiti kao sedativ za bolest putovanja.
English: Prevention of motion sickness
Croatian: Sprječavanje bolesti putovanja
English: During clinical studies maropitant plasma levels conferred efficacy from 1 hour after administration.
Croatian: Tijekom kliničkih ispitivanja razine maropitanta u plazmi odgovaraju učinkovitosti od 1 sat nakon davanja.
English: Vomiting can be associated with serious, severely debilitating conditions including gastrointestinal obstructions; therefore, appropriate diagnostic evaluations should be employed.
Croatian: Povraćanje može biti povezano s teškim i ozbiljnim stanjima koja oslabljuju organizam uključujući probavne zastoje (smetnje), zbog toga treba provesti ciljane dijagnostičke pretrage.
English: Plasma protein binding of maropitant in cats was estimated to be 99.1%.
Croatian: Vezanje proteina plazme za maropitant kod mačaka je procijenjeno na 99,1%.
English: Shelf life after first opening the vial: 28 days.
Croatian: Rok valjanosti poslije prvog otvaranja spremnika: 28 dana.
English: An unused half tablet should be returned to the opened blister and kept within the cardboard outer.
Croatian: Neiskorištenu polovinu tablete treba vratiti u već otvoreni blister, te vratiti u kartonsku kutiju.
English: Cerenia tablets were well tolerated when administered for 15 days at dosages up to 10 mg/kg bodyweight per day.
Croatian: Cerenia tablete se dobro podnose kada su davane 15 dana u dozi do 10 mg/kg tjelesne mase dnevno.
English: Following a single intravenous dose at 1 mg/kg the initial plasma concentration was 363 ng/ml.
Croatian: Nakon jedne intravenozne doze od 1 mg/kg početna koncentracije u plazmi bila je 363 ng/ml.
English: Cerenia tablets have been shown to be effective in the treatment of emesis, however where the frequency of vomiting is high, orally administered Cerenia may not be absorbed before the next vomiting event occurs.
Croatian: Cerenia tablete su se pokazale kao uspješna terapija protiv povraćanja, iako se kod slučajeva učestalog povraćanja peroralno aplicirana Cerenia možda neće apsorbirati prije slijedećeg akta povraćanja.
English: Each tablet contains 0.075% w/w Sunset Yellow (E110) as a colorant.
Croatian: Pomoćne tvari: Svaka tableta sadržava 0,075% w/w Sunset žutu (E110) kao bojilo.
English: Incidents of pre-travel vomiting, usually within two hours post-dosing were commonly reported after administration of the 8 mg/kg dose.
Croatian: Često su prijavljeni slučajevi povraćanja prije putovanja, obično unutar 2 sata nakon davanja doze od 8 mg/kg.
English: Treatment may be repeated for a maximum of two consecutive days.
Croatian: Lijek se može dati ponovo maksimalno dva uzastopna dana.
English: In vivo studies in dogs demonstrated the anti-emetic efficacy of maropitant against central and peripheral emetics including apomorphine, cisplatin and syrup of ipecac.
Croatian: In vivo ispitivanja na psima pokazuju antiemetičku djelotvornost maropitanta protiv centralnih i perifenih emetika uključujući amorfin, cispaltin i sirup ipekaka.
English: CYP1A and CYP3A-related enzymes were identified as the feline isoforms involved in the hepatic biotransformation of maropitant.
Croatian: CYP1A i CYP3A-vezani enzimi su identificirani kao mačji izoformi uključeni u jetrenu biotransformaciju maropitanta.
English: In laboratory studies, maropitant has been shown to be a potential eye irritant.
Croatian: Laboratorijska ispitivanja su pokazala da maropitant može nadražiti oči.