FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients on kidney dialysis may need to take a reduced dose.
Slovenian: Bolniki z boleznijo ledvic, ki prejemajo dializo, bodo morali jemati zmanjšan odmerek.
English: What information is still awaited for Lojuxta?
Slovenian: Katere informacije o zdravilu Lojuxta še pričakujemo?
English: For the full list of side effects, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov glejte navodilo za uporabo.
English: The active substance in Lojuxta, lomitapide, blocks the action of a substance in the body called ‘microsomal triglyceride transfer protein', which is present in the cells of the liver and the gut.
Slovenian: Zdravilna učinkovina zdravila Lojuxta, lomitapid, zavira delovanje snovi v telesu, imenovane „mikrosomalni protein za prenos trigliceridov“.
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Lojuxta, including the appropriate precautions to be followed by healthcare professionals and patients.
Slovenian: V skladu s tem načrtom so bile v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in bolniki.
English: Lojuxta can only be obtained with a prescription.
Slovenian: Izdaja zdravila Lojuxta je le na recept.
English: How is Lojuxta used?
Slovenian: Kako se zdravilo Lojuxta uporablja?
English: How does Lojuxta work?
Slovenian: Kako zdravilo Lojuxta deluje?
English: EU/2/09/102/001 GRIPOVAC 3 strains of inactivated
Slovenian: EU/2/09/102/001 GRIPOVAC 3 seve inaktiviranega virusa Influenca
English: 1GMNU = Geometric mean of neutralizing units induced in Guinea pigs after twice immunisation with 0.5 ml of this vaccine
Slovenian: ≥ 12.34 log2 GMNU1 1GMNU = Geometrijska sredina neutralizirajočih enot induciranih pri budrah po dvakratni imunizaciji z 0,5 ml tega cepiva
English: Influenza A virus/swine *
Slovenian: A/prašiči*
English: * Strains of inactivated Influenza A virus/swine/ Bakum/IDT1769/2003 (H3N2)
Slovenian: * Seve inaktiviranega virusa Influence A /prašiči/
English: What measures are being taken to ensure the safe and effective use of Natpar?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Natpar?
English: The usual recommended starting dose is 50 micrograms once a day.
Slovenian: Priporočeni začetni odmerek je 50 mikrogramov enkrat dnevno.
English: The maximum daily dose is 100 micrograms.
Slovenian: Največji dnevni odmerek je 100 mikrogramov.
English: It is not intended to provide practical advice on how to use Natpar.
Slovenian: Povzetek ni namenjen zagotavljanju praktičnih nasvetov o njegovi uporabi.
English: Other information about Natpar
Slovenian: Druge informacije o zdravilu Natpar
English: This is a summary of the European public assessment report (EPAR) for Natpar.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Natpar.
English: What is Natpar and what is it used for?
Slovenian: Kaj je zdravilo Natpar in za kaj se uporablja?
English: As a result, patients have low levels of calcium which can cause problems in bones, muscles, heart, kidneys and other parts of the body.
Slovenian: Bolniki imajo zato nizke ravni kalcija, kar lahko povzroči težave s kostmi, mišicami, srcem, ledvicami in drugimi deli telesa.
English: What benefits of Natpar have been shown in studies?
Slovenian: Kakšne koristi je zdravilo Natpar izkazalo v študijah?
English: The summary of the opinion of the Committee for Orphan Medicinal Products for Natpar can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/Rare disease designation.
Slovenian: Povzetek mnenja Odbora za zdravila sirote o zdravilu Natpar je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/Rare disease designation.
English: What are the risks associated with Natpar?
Slovenian: Kakšna tveganja so povezana z zdravilom Natpar?
English: While the main study showed that Natpar helps control blood calcium levels while reducing the need for calcium and vitamin D supplements, the study was of short duration and there was no evidence of improvements in patients' quality of life or reductions in long-term problems such as kidney impairment.
Slovenian: Čeprav je glavna študija pokazala, da zdravilo Natpar pomaga pri nadzoru ravni kalcija v krvi in zmanjšuje potrebo po nadomestkih kalcija in vitamina D, je bila študija kratkotrajna in ni bilo dokazov o izboljšanju kakovosti življenja bolnikov ali zmanjšanju dolgoročnih težav, kot je okvara ledvic.
English: Why is Natpar approved?
Slovenian: Zakaj je bilo zdravilo Natpar odobreno?
English: The company that markets Natpar will set-up a registry and collect long-term data on patients treated with Natpar, including its effects on bones, kidneys and patients' quality of life.
Slovenian: Družba, ki trži zdravilo Natpar, bo vzpostavila register in zbirala dolgoročne podatke o bolnikih, ki se zdravijo s tem zdravilom, vključno z njegovimi učinki na kosti, ledvice in kakovost življenja bolnikov.
English: The most common side effects with Natpar (which may affect more than 1 in 10 people) are too high or too low blood calcium levels, which can lead to headache, diarrhoea, vomiting, paraesthesia (unusual sensations like pins and needles), hypoaesthesia (reduced sense of touch) and high calcium levels in the urine.
Slovenian: Najpogostejši neželeni učinki zdravila Natpar (ki se lahko pojavijo pri več kot 1 bolniku od 10) so previsoke ali prenizke ravni kalcija v krvi, kar lahko povzroči glavobol, diarejo, bruhanje, parestezijo (nenavadne občutke, kot je zbadanje), hipestezijo (zmanjšan občutek za dotik) in visoko raven kalcija v urinu.
English: Because of the limited data available, Natpar has been given ‘conditional approval'.
Slovenian: Ker je na voljo omejena količina podatkov, je zdravilo Natpar pridobilo „pogojno dovoljenje za promet“.
English: Natpar parathyroid hormone
Slovenian: Natpar paratiroidni hormon
English: For more information about treatment with Natpar, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Natpar preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: The full EPAR for Natpar can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Natpar je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Natpar have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in varnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Natpar upoštevati zdravstveni delavci in bolniki, so vključeni tudi v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo.
English: Therefore, Natpar should only be used in patients who are not adequately controlled with standard treatments alone, who do not have other treatment options.
Slovenian: Zdravilo Natpar naj se zato uporablja le pri bolnikih, pri katerih bolezni ni mogoče ustrezno nadzorovati samo s standardno terapijo, in bolnikih, ki nimajo drugih možnosti zdravljenja.
English: What information is still awaited for Natpar?
Slovenian: Katere informacije o zdravilu Natpar še pričakujemo?
English: Because the number of patients with hypoparathyroidism is low, the disease is considered ‘rare', and Natpar was designated an ‘orphan medicine' (a medicine used in rare diseases) on 18 December 2013.
Slovenian: Ker je bolnikov s hipoparatiroidizmom malo, velja ta bolezen za redko, zato je bilo zdravilo Natpar 18. decembra 2013 določeno kot „zdravilo sirota“ (zdravilo za zdravljenje redkih bolezni).
English: Natpar is used as an add-on to treatment with calcium and vitamin D supplements when these treatments have not worked well enough.
Slovenian: Zdravilo Natpar se uporablja kot dodatek k zdravljenju z dopolnili kalcija in vitamina D, kadar ta zdravila niso dovolj učinkovita.
English: In a main 24-week study involving 124 patients, 54.8% (46 out of 84) of the patients who received Natpar achieved and maintained acceptable blood calcium levels while reducing their doses of calcium and vitamin D supplements by at least 50%.
Slovenian: V glavni 24-tedenski študiji, ki je vključevala 124 bolnikov, je 54,8 % bolnikov (46 bolnikov od 84), ki so prejemali zdravilo Natpar, doseglo in ohranilo ustrezne ravni kalcija ob vsaj 50-odstotnem zmanjšanju odmerkov dopolnil kalcija in vitamina D. Delež bolnikov, ki so prejemali placebo (zdravilo brez zdravilne učinkovine) in so dosegli enake rezultate, je bil 2,5 % (1 bolnik od 40).
English: How does Natpar work?
Slovenian: Kako zdravilo Natpar deluje?
English: In patients with this condition, the parathyroid glands in the neck do not produce enough parathyroid hormone which controls the level of calcium in the blood.
Slovenian: Pri bolnikih s to boleznijo paratiroidne žleze v vratu ne proizvajajo dovolj paratiroidnega hormona, ki uravnava raven kalcija v krvi.
English: Natpar must not be used in patients who are having or have had radiation therapy to the bones, who have bone cancer or cancer that has spread to the bones and are at increased risk of developing a bone cancer called osteosarcoma.
Slovenian: Zdravilo Natpar se ne sme uporabljati pri bolnikih, ki se zdravijo ali so se zdravili z obsevanjem kosti, ki imajo kostnega raka ali raka, ki se je razširil na kosti, in ki jih ogroža tveganje za nastanek kostnega raka, imenovanega osteosarkom.
English: Natpar must also not be used in patients who have unexplained increases in the levels of an enzyme called bone alkaline phosphatase and those who have pseudohypoparathyroidism, a rare disease where the body does not respond adequately to the parathyroid hormone produced by the body.
Slovenian: Zdravilo Natpar se prav tako ne sme uporabljati pri bolnikih, ki imajo nepojasnjene zvišane ravni encima, imenovanega kostna alkalna fosfataza, in tistih, ki imajo psevdohipoparatiroidizem, redko bolezen, pri kateri se telo neustrezno odziva na paratiroidni hormon, ki nastaja v telesu.
English: The active substance in Natpar, parathyroid hormone, is a copy of the natural hormone produced by the parathyroid glands.
Slovenian: Zdravilna učinkovina v zdravilu Natpar, paratiroidni hormon, je kopija naravnega hormona, ki ga proizvajajo paratiroidne žleze.
English: Natpar has been shown to help control blood calcium levels in patients with hypoparathyroidism who are receiving calcium and vitamin D supplements.
Slovenian: Zdravilo Natpar pomaga pri nadzoru ravni kalcija v krvi pri bolnikih s hipoparatiroidizmom, ki prejemajo dopolnila kalcija in vitamina D.
English: For practical information about using Natpar, patients should read the package leaflet or contact their doctor or pharmacist.
Slovenian: Za praktične informacije o uporabi zdravila Natpar naj bolniki preberejo navodilo za uporabo ali se posvetujejo z zdravnikom ali farmacevtom.
English: The medicine can only be obtained with a prescription and treatment should be supervised by a healthcare professional experienced in the management of patients with hypoparathyroidism.
Slovenian: Predpisovanje in izdaja zdravila Natpar je le na recept, zdravljenje z njim pa mora nadzorovati zdravnik, ki ima izkušnje z zdravljenjem bolnikov s hipoparatiroidizmom.
English: Patients can inject Natpar themselves once they have been trained.
Slovenian: Bolniki si lahko po ustreznem usposabljanju zdravilo Natpar injicirajo sami.
English: Since Natpar has been granted a conditional approval, the company that markets Natpar will conduct a further study to confirm the benefits and risks of the medicine and the appropriateness of the once-aday dosing schedule.
Slovenian: Ker je zdravilo Natpar pridobilo pogojno dovoljenje za promet, bo družba, ki ga trži, izvedla dodatno raziskavo za potrditev tveganj in koristi zdravila ter primernosti odmerjanja enkrat dnevno.
English: How is Natpar used?
Slovenian: Kako se zdravilo Natpar uporablja?
English: Natpar is available as a powder and a liquid that are mixed together to make a solution for injection.
Slovenian: Zdravilo Natpar je na voljo v obliki praška in vehikla, ki se zmešata v raztopino za injiciranje.
English: Natpar is a hormone replacement medicine for treating adults with under-active parathyroid glands, a condition known as hypoparathyroidism.
Slovenian: Zdravilo Natpar je hormonski nadomestek za zdravljenje odraslih s premalo delujočimi obščitničnimi (paratiroidnimi) žlezami, tj. boleznijo, znano kot hipoparatiroidizem.
English: It replaces the missing hormone in patients with hypoparathyroidism, thus helping to restore calcium levels.
Slovenian: Pri bolnikih s hipoparatiroidizmom nadomešča manjkajoči hormon in tako pomaga uravnavati raven kalcija.
English: For the full list of all side effects reported with Natpar, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Natpar, glejte navodilo za uporabo.
English: Natpar replaces the missing parathyroid hormone in patients with hypoparathyroidism.
Slovenian: Zdravilo Natpar nadomešča pomanjkanje paratiroidnega hormona pri bolnikih s hipoparatiroidizmom.
English: and calcium supplements, is then adjusted on the basis of the patient's blood calcium levels.
Slovenian: Odmerek zdravila Natpar in bolnikov odmerek dopolnil vitamina D in kalcija se nato prilagajo glede na raven kalcija v bolnikovi krvi.
English: Regarding safety, the risk of calcium levels becoming too high or too low is considered important and further data are needed to better understand the consequences of wide fluctuations in blood calcium level after the medicine is given once a day.
Slovenian: Za boljše razumevanje posledic izrazitega nihanja ravni kalcija v krvi po dajanju zdravila enkrat dnevno bodo potrebni nadaljnji podatki.
English: Natpar contains the active substance parathyroid hormone.
Slovenian: Zdravilo Natpar vsebuje zdravilno učinkovino paratiroidni hormon.
English: Natpar is injected under the skin of the thigh using the Natpar pen.
Slovenian: Zdravilo Natpar se s peresnikom Natpar injicira pod kožo stegna.
English: Then carry on as usual the next day.
Slovenian: Nato nadaljujte kot običajno naslednji dan.
English: These measures will help protect the environment
Slovenian: Takšni ukrepi pomagajo varovati okolje.
English: 90% Confidence Interval
Slovenian: 90-% interval zaupanja
English: Elderly population (> 65 years)
Slovenian: Starejša populacija (> 65 let)
English: There are only very few data available on patients with African origin.
Slovenian: Na voljo je zelo malo podatkov za bolnike afriškega izvora.
English: % of Patients with Response
Slovenian: % bolnikov z odgovorom
English: Infusion Volume 1 and Time 2
Slovenian: Volumen infuzije 1 in čas 2
English: After reconstitution: 24 hours.
Slovenian: Po rekonstituciji: 24 ur.
English: The dose is determined by the doctor considering the following factors.
Slovenian: Odmerek določi zdravnik z upoštevanjem naslednjih dejavnikov.
English: From a microbiological point of view, the product should be used immediately.
Slovenian: Z mikrobiološkega vidika moramo zdravilo uporabiti takoj.
English: These symptoms usually disappear within a couple of hours or days.
Slovenian: Ti simptomi ponavadi izginejo v nekaj urah ali dneh.
English: Number of events (per patient)
Slovenian: Število dogodkov (na bolnika)
English: • Take your tablet with a full glass of water only (about 200 mL).
Slovenian: • vzamete tableto samo s polnim kozarcem vode (približno 200 ml).
English: Do not let the tablet dissolve in your mouth
Slovenian: Ne pustite, da se tableta raztopi v ustih.
English: No data are available .
Slovenian: Podatki niso na voljo.
English: Date of first authorisation: 21 January 2011 Date of latest renewal: 30 September 2015
Slovenian: Datum prve odobritve: 21. januar 2011 Datum zadnjega podaljšanja: 30. september 2015
English: Lactose monohydrate Macrogol 4000
Slovenian: Laktoza monohidrat Makrogol 4000
English: While on treatment, these patients should avoid invasive dental procedures if possible.
Slovenian: Med zdravljenjem naj se ti bolniki, če je le mogoče, izogibajo invazivnim zobozdravstvenim posegom.
English: Quality of Life *
Slovenian: kakovost življenja *
English: 5 years.
Slovenian: 5 leti
English: 100 ml over 15 minutes
Slovenian: 100 ml v 15 minutah
English: In clinical trials, therapy has continued for up to 96 weeks.
Slovenian: V kliničnih preskušanjih je zdravljenje potekalo do 96 tednov.
English: The usual dose of Iasibon is one tablet each day.
Slovenian: Običajni odmerek zdravila Iasibon je ena tableta vsak dan.
English: If you develop these symptoms, stop taking Iasibon and tell your doctor straight away (see sections 3 and 4).
Slovenian: Če se pojavijo ti simptomi, prenehajte z jemanjem zdravila Iasibon in takoj obvestite svojega zdravnika (glejte poglavji 3 in 4).
English: They are available in packs of 3, 6, 9, 28 and 84 tablets.
Slovenian: Na voljo so v pakiranjih po 3, 6, 9, 28 in 84 tablet.
English: Multiple events were therefore counted only once for the purposes of the analysis.
Slovenian: Večkratne dogodke so zaradi analize upoštevali le enkrat.
English: If the dates for submission of a PSUR and the update of a RMP coincide, they can be submitted at the same time.
Slovenian: Če predložitev PSUR in posodobitev RMP sovpadata, se ju lahko predloži istočasno.
English: Film-coated tablets 3 film-coated tablets 6 film-coated tablets 9 film-coated tablets 28 film-coated tablets 84 film-coated tablets
Slovenian: Filmsko obložene tablete 3 filmsko obložene tablete 6 filmsko obloženih tablet 9 filmsko obloženih tablet 28 filmsko obloženih tablet 84 filmsko obloženih tablet
English: • Swallow the tablet whole.
Slovenian: • pogoltnete celo tableto.
English: If you are taking a tablet every other day or once a week, ask your doctor or pharmacist for advice.
Slovenian: Če jemljete tablete vsak drugi dan ali enkrat na teden, vprašajte vašega zdravnika ali farmacevta za nasvet.
English: When taken 30 minutes before a meal, the reduction in bioavailability is approximately 30%.
Slovenian: Pri jemanju 30 minut pred obrokom je zmanjšanje biološke uporabnosti približno 30-%.
English: 500 ml over 1 hour
Slovenian: 500 ml v 1 uri
English: Maximum observed plasma concentrations were reached within 0.5 to 2 hours (median 1 hour) in the fasted state and absolute bioavailability was about 0.6%.
Slovenian: Najvišje plazemske koncentracije so bile med postom dosežene v obdobju od 0,5 do 2 ur (mediana časa 1 ura), absolutna biološka uporabnost je bila okoli 0,6 %.
English: SMPR (per patient year)
Slovenian: SMPR (na bolnikovo leto)
English: • rise in body temperature.
Slovenian: • zvišanje telesne temperature,
English: Hypromellose (E464) Titanium dioxide E171
Slovenian: Hipromeloza (E464) Titanov dioksid (E171)
English: The extent of absorption is impaired when taken together with food or beverages (other than water).
Slovenian: Obseg absorpcije je pri sočasnem jemanju hrane ali pijače (druge kot voda) zmanjšan.
English: If anaphylactic or other severe hypersensitivity/allergic reactions occur, immediately discontinue the injection and initiate appropriate treatment.
Slovenian: Če pride do pojava anafilaktične ali druge hude preobčutljivostne/alergijske reakcije, takoj prekinite z injiciranjem in začnite z ustreznim zdravljenjem.
English: As renal function decreases with age, this is the only factor that should be considered (see renal impairment section).
Slovenian: Ker se ledvična funkcija z leti zmanjšuje, je to edini dejavnik, ki ga je treba upoštevati (glejte odstavek ledvične okvare).
English: However, the marketing authorisation holder shall submit periodic safety update reports for this medicinal product if the product is included in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and published on the European medicines web-portal.
Slovenian: • Redno posodobljena poročila o varnosti zdravila (PSUR) Imetnik dovoljenja za promet z zdravilom mora redno posodobljena poročila o varnosti zdravila za to zdravilo predložiti v skladu z zahtevami, določenimi v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES in objavljenem na evropskem spletnem portalu o zdravilih.
English: A limited number of patients (50 patients) have received a second infusion for hypercalcaemia.
Slovenian: Omejeno število bolnikov (50 bolnikov) je prejelo drugo infuzijo zaradi hiperkalciemije.
English: Creatinine Clearance (ml/min)
Slovenian: Očistek kreatinina (ml/min)
English: In particular, tell your doctor or pharmacist if you are taking any of the following medicines:
Slovenian: Še posebej obvestite svojega zdravnika ali farmacevta, če jemljete katerekoli izmed naslednjih zdravil:
English: Iasibon is indicated in adults for:
Slovenian: 4.1 Terapevtske indikacije Iasibon je indiciran pri odraslih za:
English: • Do not use this medicine if you notice that the solution is not clear or contains particles.
Slovenian: • Ne uporabljajte tega zdravila ,če opazite, da raztopina ni bistra ali vsebuje vidne delce.
English: Do not lie down.
Slovenian: Ne izzovite bruhanja in ne lezite.
English: • increased sensitivity of sound, taste or touch or changes in smell
Slovenian: • povečana občutljivost na zvok, okus ali dotik ali spremembe zaznavanja vonja,
English: Water may be taken at any time during the course of Iasibon treatment (see section 4.5).
Slovenian: Vodo lahko med zdravljenjem z zdravilom Iasibon pijemo kadarkoli (glejte poglavje 4.5).
English: Pharmathen International S.A. Industrial Park Sapes, Street block 5 69300 Sapes, Prefecture of Rodopi Greece
Slovenian: Pharmathen International S.A. Industrial Park Sapes, Street block 5 693 00 Sapes, Rodopi
English: • supplements containing calcium, magnesium, iron or aluminium
Slovenian: • dodatke, ki vsebujejo kalcij, magnezij, železo ali aluminij;
English: - The tablets should be swallowed whole with a full glass of water (180 to 240 ml) while the patient is standing or sitting in an upright position.
Slovenian: - Tablete je treba pogoltniti cele s polnim kozarcem navadne vode (180 do 240 ml), bolnik mora pri tem stati ali sedeti pokončno.
English: After taking your tablet, wait at least 30 minutes.
Slovenian: ko vzamete tableto, počakajte vsaj 30 minut.
English: Not known (frequency cannot be estimated from the available data) • asthma attack
Slovenian: Ni znano (pogostnosti ni mogoče oceniti iz razpoložljivih podatkov):
English: • Iasibon is normally given by a doctor or other medical staff who have experience with the treatment of cancer.
Slovenian: • Zdravilo Iasibon običajno aplicira zdravnik ali drugo medicinsko osebje, ki ima izkušnje pri zdravljenju raka..
English: The highest dose used in clinical trials was 6 mg but this dose does not add any further benefit in terms of efficacy.
Slovenian: Največji odmerek, ki so ga dajali v kliničnih preskušanjih, je bil 6 mg, vendar ta odmerek ni prispeval k nadaljnjemu izboljšanju glede učinkovitosti.
English: Repeated treatment may be considered in case of recurrent hypercalcaemia or insufficient efficacy.
Slovenian: Ponovitev zdravljenja pride v poštev v primeru povratne hiperkalciemije ali nezadostne učinkovitosti.
English: Renal clearance (about 60 ml/min in healthy postmenopausal females) accounts for 50-60% of total clearance and is related to creatinine clearance.
Slovenian: Ledvični očistek (okoli 60 ml/min pri zdravih ženskah v postmenopavzi) znaša okoli 50 do 60 % celotnega očistka in je soroden kreatininskemu očistku.
English: Iasibon tablets should be taken after an overnight fast (at least 6 hours) and before the first food or drink of the day.
Slovenian: Tablete Iasibon je treba vzeti po postu prek noči (najmanj 6 ur) pred prvim zaužitjem hrane ali pijače v dnevu.