FrancophonIA/ELRC3.0 huggingface dataset:
English: After repeated once-daily administration of 40 mg esomeprazole, the mean area under the plasma concentration-time curve was approximately 100% higher in poor metabolisers than in subjects having a functional CYP2C19 enzyme (extensive metabolisers).
Croatian: Nakon višekratne primjene doze od 40 mg esomeprazola jedanput na dan prosječna vrijednost površine ispod krivulje bila je otprilike 100% veća u sporih metabolizatora nego u ispitanika u kojih je enzim CYP2C19 funkcionalan (brzi metabolizatori).
English: • You may need to take the capsules for 2 or 3 days in a row before your reflux symptoms (for example, heartburn and acid regurgitation) get better.
Croatian: • Kapsule ćete možda morati uzimati 2 ili 3 dana zaredom prije nego što osjetite poboljšanje simptoma refluksa (primjerice, žgaravice i povrata želučane kiseline).
English: Pack sizes of 7 and 14 gastro-resistant tablets.
Croatian: Veličine pakiranja: 7 i 14 želučanootpornih tableta.
English: • They have significant unintentional weight loss, recurrent vomiting, dysphagia, haematemesis or melaena and when gastric ulcer is suspected or present, malignancy should be excluded as treatment with esomeprazole may alleviate symptoms and delay diagnosis.
Croatian: • u slučaju značajnog neplaniranog gubitka težine, opetovanog povraćanja, disfagije, hematemeze ili melene te kod sumnje na želučani ulkus ili postojanja želučanog ulkusa, potrebno je isključiti maligne bolesti, jer liječenje esomeprazolom može ublažiti simptome i odgoditi postavljanje dijagnoze.
English: • Low levels of sodium in the blood.
Croatian: • niske razine natrija u krvi.
English: • Cilostazol (used to treat intermittent claudication - a condition where poor blood supply to the leg muscles causes pain and difficulty in walking).
Croatian: • Cilostazol (koristi se za liječenje intermitentne klaudikacije - stanja u kojem nedostatna opskrba krvlju mišića nogu uzrokuje bol u nogama i probleme pri hodanju).
English: Animal studies with the racemic mixture omeprazole, given by oral administration do not indicate effects with respect to fertility.
Croatian: Istraživanja na životinjama u kojima se ispitivala peroralno primijenjena racemična smjesa omeprazola nisu ukazala na učinke povezane s plodnošću.
English: A light pink, oblong, biconvex, film-coated, gastro-resistant tablet of 14 mm x 7 mm engraved with ‘20 mG' on one side and ‘A/EH' on the other side.
Croatian: Svijetloružičasta, duguljasta, bikonveksna, filmom obložena, želučanootporna tableta veličine 14 mm x 7 mm s utisnutom oznakom „20 mG“ na jednoj i „A/EH“ na drugoj strani.
English: Following a single dose of 40 mg esomeprazole the mean are under the plasma concentration-time curve is approximately 30% higher in females than in males.
Croatian: Nakon jednokratne doze od 40 mg esomeprazola prosječna vrijednost površine ispod krivulje je približno 30% veća u žena nego u muškaraca.
English: • The active substance is esomeprazole.
Croatian: • Djelatna tvar je esomeprazol.
English: • Dizziness, tingling feelings such as “pins and needles”.
Croatian: • omaglica, osjećaj trnaca „poput bockanja iglicama“
English: For 20 mg esomeprazole the corresponding values are 50% and 68% respectively.
Croatian: Za dozu od 20 mg esomeprazola odgovarajuće vrijednosti bioraspoloživosti su 50% odnosno 68%.
English: What can I do to help relieve my symptoms?
Croatian: Kako možete olakšati simptome žgaravice?
English: Concomitant administration of 40 mg esomeprazole resulted in a 13% increase in trough plasma levels of phenytoin in epileptic patients.
Croatian: Istodobna primjena 40 mg esomeprazola povećala je za 13% najnižu koncentraciju fenitoina u plazmi u bolesnika s epilepsijom.
English: Do not take Nexium Control
Croatian: Nemojte uzimati Nexium Control
English: • Cilostazol (used to treat intermittent claudication - a condition where poor blood supply to the leg muscles causes pain and difficulty in walking)
Croatian: • Cilostazol (koristi se za liječenje intermitentne klaudikacije - stanja u kojem nedostatna opskrba krvlju mišića nogu uzrokuje bol u nogama i probleme pri hodanju)
English: This can cause weakness, bruising, or make infections more likely.
Croatian: To može uzrokovati slabost i stvaranje modrica ili povećati sklonost infekcijama.
English: • Effects on your stomach or gut: diarrhoea, stomach ache, constipation, wind (flatulence).
Croatian: • učinci na želudac ili crijeva: proljev, bol u želucu, zatvor, vjetrovi (flatulencija)
English: Nexium Control is not meant to bring immediate relief.
Croatian: Nexium Control nije namijenjen za trenutačno ublažavanje simptoma.
English: Your doctor may need to monitor you when you start or stop taking Nexium Control.
Croatian: Liječnik će Vas možda morati nadzirati kada započnete ili prekinete liječenje lijekom Nexium Control.
English: Excipient(s) with known effect Each gastro-resistant tablet contains 28 mg sucrose.
Croatian: Pomoćna(e) tvar(i) s poznatim učinkom Jedna želučanootporna tableta sadrži 28 mg saharoze.
English: • You may need to take the tablets for 2 or 3 days in a row before your reflux symptoms (for example, heartburn and acid regurgitation) get better.
Croatian: • Tablete ćete možda morati uzimati 2 ili 3 dana zaredom prije nego što osjetite poboljšanje simptoma refluksa (primjerice, žgaravice i povrata želučane kiseline).
English: Omeprazole (40 mg once daily) increased voriconazole (a CYP2C19 substrate) Cmax and AUCτ by 15% and 41%, respectively.
Croatian: Omeprazol (u dozi od 40 mg jedanput na dan) je povećao Cmax vorikonazola (supstrata CYP2C19) za 15%, a njegov AUCτ za 41%.
English: The pharmacokinetics of esomeprazole has been studied in doses up to 40 mg b.i.d.
Croatian: Farmakokinetika esomeprazola ispitivana je u dozama do 40 mg dvaput na dan.
English: • Digoxin (used for heart problems)
Croatian: • Digoksin (koristi se za srčane tegobe)
English: Esomeprazole inhibits CYP2C19, the major esomeprazole metabolising enzyme.
Croatian: Esomeprazol inhibira CYP2C19, glavni enzim koji metabolizira esomeprazol.
English: • Digoxin (used for heart problems).
Croatian: • Digoksin (koristi se za srčane tegobe).
English: Capsule approximately 11 x 5 mm, with a clear body, and an amethyst cap imprinted with “NEXIUM 20 MG” in white.
Croatian: Kapsula veličine približno 11 x 5 mm sa prozirnim tijelom i ljubičastom kapicom na kojoj je bijelom tintom otisnuto “NEXIUM 20 MG”.
English: Medicinal products known to induce CYP2C19 or CYP3A4 or both (such as rifampicin and St. John's wort (Hypericum perforatum)) may lead to decreased esomeprazole serum levels by increasing the esomeprazole metabolism.
Croatian: Lijekovi za koje se zna da induciraju CYP2C19, CYP3A4 ili oba izoenzima (poput rifampicina i gospine trave (Hypericum perforatum)) mogu povećati metabolizam esomeprazola i tako smanjiti njegovu koncentraciju u serumu.
English: In a study in healthy subjects, there was a decreased exposure by almost 40% of the active metabolite of clopidogrel when a fixed dose combination of esomeprazole 20 mg + acetylsalicylic acid 81 mg was given with clopidogrel compared to clopidogrel alone.
Croatian: U ispitivanju u zdravih ispitanika primijećeno je smanjenje izloženosti aktivnom metabolitu klopidogrela od gotovo 40% kada se uz klopidogrel davala fiksna kombinacija 20 mg esomeprazola + 81 mg acetilsalicilne kiseline u usporedbi s primjenom samo klopidogrela.
English: Concomitant administration of 30 mg esomeprazole resulted in a 45% decrease in clearance of the CYP2C19 substrate diazepam.
Croatian: Istodobna primjena 30 mg esomeprazola uzrokovala je 45% manji klirens diazepama, supstrata CYP2C19.
English: Reproductive system and breast disorders gynaecomastia
Croatian: Poremećaji reproduktivnog sustava i dojki ginekomastija
English: Blood and lymphatic system disorders leukopenia, thrombocytopenia agranulocytosis, pancytopenia
Croatian: Poremećaji krvi i limfnog sustava leukopenija, trombocitopenija agranulocitoza pancitopenija
English: Carcinogenicity studies in the rat with the racemic mixture have shown gastric ECL-cell hyperplasia and carcinoids.
Croatian: Ispitivanja kancerogenosti na štakorima uz primjenu racemične smjese ukazala su na hiperplaziju želučanih stanica nalik na enterokromafine stanice i karcinoide.
English: Esomeprazole must not be used concomitantly with nelfinavir (see section 4.5).
Croatian: Esomeprazol se ne smije primjenjivati istodobno s nelfinavirom (vidjeti dio 4.5).
English: Nervous system disorders headache dizziness, paraesthesia, somnolence taste disturbance
Croatian: Poremećaji živčanog sustava glavobolja omaglica, parestezije, somnolencija poremećaj okusa
English: You may experience symptoms such as diarrhoea, stomach ache, constipation, feeling or being sick and weakness.
Croatian: Mogli biste osjetiti simptome (kao što su proljev, bol u želucu, zatvor, mučnina ili povraćanje) i slabost.
English: These gastric effects in the rat are the result of sustained, pronounced hypergastrinaemia secondary to reduced production of gastric acid and are observed after long-term treatment in the rat with inhibitors of gastric acid secretion.
Croatian: Ove promjene su rezultat trajne izrazite hipergastrinemije koja je posljedica smanjenog lučenja želučane kiseline, a primijećene su nakon dugotrajne primjene inhibitora lučenja želučane kiseline u štakora.
English: Proton pump inhibitors are associated with very infrequent cases of SCLE.
Croatian: Subakutni kožni lupus eritematodes (engl. subacute cutaneous lupus erythematosus, SCLE) Inhibitori protonske pumpe povezani su s vrlo rijetkim slučajevima SCLE-a.
English: Nexium Control is indicated for the short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults.
Croatian: Nexium Control je indiciran za kratkotrajno liječenje simptoma refluksa (npr. žgaravice i regurgitacije želučane kiseline) u odraslih.
English: • Voriconazole (used to treat infections caused by a fungus) and clarithromycin (used to treat infections).
Croatian: • Vorikonazol (koristi se za liječenje gljivičnih infekcija) i klaritromicin (koristi se za liječenje infekcija).
English: You may need to take the capsules for 2-3 days in a row before you feel better.
Croatian: Kapsule ćete možda morati uzimati 2-3 dana zaredom prije nego što osjetite poboljšanje.
English: Medicinal products which induce CYP2C19 and/or CYP3A4
Croatian: Lijekovi koji induciraju CYP2C19 i/ili CYP3A4
English: Your doctor may need to monitor you when you start or stop taking Nexium Control
Croatian: Liječnik će Vas možda morati nadzirati kada započnete ili prekinete liječenje lijekom Nexium Control
English: • Suddenly feeling wheezy or short of breath (bronchospasm).
Croatian: • iznenadno piskanje pri disanju ili nedostatak zraka (bronhospazam)
English: Investigated medicinal products with no clinically relevant interaction Amoxicillin and quinidine
Croatian: Ispitivani lijekovi kod kojih ne dolazi do klinički značajne interakcije Amoksicilin i kinidin
English: In both studies esomeprazole 20 mg was significantly better compared to placebo for the primary endpoint, complete resolution of heartburn, defined as no heartburn episodes during the last 7 days prior to the final visit (33.9% - 41.6% vs. placebo 11.9 - 13.7%, (p<0.001).
Croatian: U oba je ispitivanja esomeprazol u dozi od 20 mg postigao značajno bolje rezultate u usporedbi s placebom u primarnoj mjeri ishoda, potpunom povlačenju žgaravice što se definira kao izostanak epizode žgaravice tijekom posljednjih 7 dana prije završnog posjeta (33,9%41,6% u odnosu na 11,9-13,7% u bolesnika koji su primali placebo, (p<0,001).
English: Musculoskeletal and connective tissue disorders arthralgia, myalgia muscular weakness
Croatian: Poremećaji mišićnokoštanog sustava i vezivnog tkiva artralgija, mialgija mišićna slabost
English: The co-administration of omeprazole (20 mg once a day) with atazanavir 400 mg/ritonavir 100 mg to healthy volunteers resulted in a decrease of approximately 30% in the atazanavir exposure as compared with the exposure observed with atazanavir 300 mg/ritonavir 100 mg once a day without omeprazole 20 mg once a day.
Croatian: Istodobna primjena omeprazola (20 mg jedanput na dan) i 400 mg atazanavira/100 mg ritonavira u zdravih dobrovoljaca dovela je do smanjenja izloženosti atazanaviru od približno 30% u usporedbi s izloženošću koja je primijećena kod primjene 300 mg atazanavira/100 mg ritonavira jedanput na dan bez omeprazola u dozi od 20 mg jedanput na dan.
English: Single doses of 80 mg esomeprazole were uneventful.
Croatian: Pojedinačne doze od 80 mg esomeprazola nisu uzrokovale simptome.
English: - You must talk to a doctor if you do not feel better or if you feel worse after 14 days.
Croatian: Pogledajte dio 4. - Obavezno se obratite liječniku ako se ne osjećate bolje ili ako se osjećate lošije nakon 14 dana.
English: • You are taking any medicines listed in the package leaflet.
Croatian: • Ako uzimate bilo koji lijek naveden u uputi o lijeku.
English: Gastric acid suppression during treatment with esomeprazole and other PPIs might decrease or increase the absorption of medicinal products with a gastric pH dependent absorption.
Croatian: Supresija želučane kiseline tijekom liječenja esomeprazolom i drugim inhibitorima protonske pumpe može smanjiti ili povećati apsorpciju lijekova kod kojih ona ovisi o pH.
English: This is because the capsule contains coated pellets, which stop the medicine from being broken down by the acid in your stomach.
Croatian: Naime, kapsule sadrže obložene pelete, koje sprječavaju kiselinu u želucu da razgradi lijek.
English: Treatment with PPIs may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter and in hospitalised patients, also possibly Clostridium difficile.
Croatian: Liječenje inhibitorima protonske pumpe može dovesti do blagog povećanja rizika od gastrointestinalnih infekcija, poput infekcija bakterijama Salmonella i Campylobacter, a u hospitaliziranih bolesnika i do moguće infekcije bakterijom Clostridium difficile.
English: Do not use this medicine after the expiry date which is stated on the carton and the bottle after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici iza oznake „Rok valjanosti“ i „EXP“.
English: Nexium Control contains the active substance esomeprazole.
Croatian: Nexium Control sadrži djelatnu tvar esomeprazol.
English: EU/1/13/860/001 7 gastro-resistant tablets EU/1/13/860/002 14 gastro-resistant tablets
Croatian: EU/1/13/860/001 7 želučanootpornih tableta EU/1/13/860/002 14 želučanootpornih tableta
English: However, post-marketing, a few isolated cases of elevated INR of clinical significance have been reported during concomitant treatment.
Croatian: Međutim, nakon stavljanja lijeka u promet, kod istodobnoga su liječenja prijavljeni izolirani klinički značajni slučajevi povećanoga INR-a.
English: Pfizer Gyógyszerkereskedelmi Kft. Consumer Healthcare Tel.: +36 1 488 37 00
Croatian: Consumer Healthcare Tel.: +36 1 488 37 00
English: Keep the container tightly closed to protect from moisture.
Croatian: Čuvati u čvrsto zatvorenoj bočici radi zaštite od vlage.
English: What Nexium Control contains - The active substance is esomeprazole.
Croatian: Što Nexium Control sadrži - Djelatna tvar je esomeprazol.
English: Esomeprazole has minor influence on the ability to drive or use machines.
Croatian: Esomeprazol slabo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: • You have severe kidney problems.
Croatian: • Ako imate teške probleme s bubrezima.
English: Dose adjustment is not required in patients with mild to moderate liver impairment.
Croatian: Nije potrebno prilagođavati dozu u bolesnika s blagim do umjerenim oštećenjem jetre.
English: Posology The recommended dose is 20 mg esomeprazole (one tablet) per day.
Croatian: Doziranje Preporučena doza je 20 mg esomeprazola (jedna tableta) na dan.
English: • Diazepam (used to treat anxiety, relax muscles or in epilepsy)
Croatian: • Diazepam (koristi se za liječenje tjeskobe, opuštanje mišića ili kod liječenja epilepsije)
English: • Diazepam (used to treat anxiety, relax muscles or in epilepsy).
Croatian: • Diazepam (koristi se za liječenje tjeskobe, opuštanje mišića ili kod liječenja epilepsije).
English: What Nexium Control looks like and contents of the pack Nexium Control 20 mg gastro-resistant tablets are light pink, oblong, biconvex, 14 mm x 7 mm, filmcoated, engraved with ‘20 mG' on one side and A/EH on the other side.
Croatian: Kako Nexium Control izgleda i sadržaj pakiranja Nexium Control 20 mg želučanootporne tablete su svijetloružičaste, ovalne, bikonveksne i filmom obložene, veličine 14 mm x 7 mm s utisnutom oznakom „20 mG“ na jednoj i „A/EH“ na drugoj strani.
English: • Put the tablet in a glass of still (non-fizzy) water.
Croatian: • Stavite tabletu u čašu negazirane vode.
English: Posology The recommended dose is 20 mg esomeprazole (one capsule) per day.
Croatian: Doziranje Preporučena doza je 20 mg esomeprazola (jedna kapsula) na dan.
English: Esomeprazole is metabolised by CYP2C19 and CYP3A4.
Croatian: Esomeprazol se metabolizira putem CYP2C19 i CYP3A4.
English: What Nexium Control looks like and contents of the pack Nexium Control 20 mg gastro-resistant hard capsules are approximately 11 x 5 mm capsules with a clear body, and an amethyst cap imprinted with “NEXIUM 20 MG” in white.
Croatian: Kako Nexium Control izgleda i sadržaj pakiranja Nexium Control 20 mg želučanootporne tvrde kapsule su kapsule veličine približno 11 x 5 mm s prozirnim tijelom i ljubičastom kapicom na kojoj je bijelom tintom otisnuto „NEXIUM 20 MG“.
English: The proportion of patients maintaining an intragastric pH above 4 for at least 8, 12 and 16 hours respectively were for esomeprazole 20 mg 76%, 54%, and 24%.
Croatian: Udio bolesnika u kojih je uz esomeprazol u dozi od 20 mg unutarželučani pH održan iznad vrijednosti 4 tijekom najmanje 8, 12 odnosno 16 sati iznosio je 76%, 54% odnosno 24%.
English: Concomitant administration of esomeprazole and a combined inhibitor of CYP2C19 and CYP3A4 may result in more than doubling of the esomeprazole exposure.
Croatian: Istodobna primjena esomeprazola i kombiniranog inhibitora CYP2C19 i CYP3A4 može više nego dvostruko povećati izloženost esomeprazolu.
English: You may need to take the tablets for 2-3 days in a row before you feel better.
Croatian: Tablete ćete možda morati uzimati 2-3 dana zaredom prije nego što osjetite poboljšanje.
English: • Sudden wheezing, swelling of your lips, tongue and throat, rash, fainting, or difficulties in swallowing (severe allergic reaction, seen rarely).
Croatian: • iznenadno piskanje pri disanju, oticanje usana, jezika i grla, osip, nesvjesticu ili otežano gutanje (teška alergijska reakcija, javlja se rijetko).
English: • Joint pain (arthralgia) or muscle pain (myalgia).
Croatian: • bol u zglobovima (artralgija) ili bol u mišićima (mijalgija)
English: Titanium dioxide (E171)
Croatian: talk titanijev dioksid (E171) trietilcitrat
English: Treatment with omeprazole 20 mg once a day had no effect on the exposure of darunavir (with concomitant ritonavir) and amprenavir (with concomitant ritonavir).
Croatian: Liječenje omeprazolom u dozi od 20 mg jedanput na dan nije utjecalo na izloženost darunaviru (primijenjenim zajedno s ritonavirom) niti amprenaviru (primijenjenim zajedno s ritonavirom).
English: No dose-related adverse reactions have been identified.
Croatian: Nisu primijećene nuspojave ovisne o dozi.
English: • Sudden wheezing, swelling of your lips, tongue and throat, rash, fainting or difficulties in swallowing (severe allergic reaction, seen rarely)
Croatian: • iznenadno piskanje pri disanju, oticanje usana, jezika i grla, osip, nesvjesticu ili otežano gutanje (teška alergijska reakcija, javlja se rijetko)
English: This is because the tablet contains coated pellets, which stop the medicine from being broken down by the acid in your stomach.
Croatian: Naime, tablete sadrže obložene pelete, koje sprječavaju kiselinu u želucu da razgradi lijek.
English: For atazanavir and nelfinavir, decreased serum levels have been reported when given together with omeprazole and concomitant administration is not recommended.
Croatian: Kad su se davali zajedno s omeprazolom, zabilježene su niže serumske razine atazanavira i nelfinavira pa se istodobna primjena ne preporučuje.
English: • The other ingredients are: glycerol monostearate 40-55, hydroxypropylcellulose, hypromellose, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1) dispersion 30 per cent, polysorbate 80, sugar spheres (sucrose and maize starch), talc, triethyl citrate, carmine (E120), indigo carmine (E132), titanium dioxide (E171), yellow iron oxide (E172), erythrosine (E127), allura red AC (E129), povidone K-17, propylene glycol, shellac, sodium hydroxide, and gelatin (see section 2, “Nexium Control contains sucrose”.)
Croatian: • Drugi sastojci su: glicerolmonostearat 40-55, hidroksipropilceluloza, hipromeloza, magnezijev stearat, metakrilatna kiselina- etilakrilat kopolimer (1:1); 30 postotna disperzija, polisorbat 80, šećerne kuglice (saharoza i kukuruzni škrob), talk, trietilcitrat, karmin (E120), bojilo Indigo carmine (E132), titanijev dioksid (E171), žuti željezov oksid (E172), bojilo Erythrosine (E127), bojilo Allura red AC (E129), povidon K-17, propilenglikol, šelak, natrijev hidroksid i želatina (Pogledajte dio 2, „Nexium Control sadrži saharozu”.)
English: Very rare (may affect up to 1 in 10,000 people)
Croatian: Vrlo rijetke (mogu se javiti u manje od 1 na 10 000 osoba):
English: • Citalopram, imipramine or clomipramine (used to treat depression)
Croatian: • Citalopram, imipramin ili klomipramin (koriste se za liječenje depresije)
English: Gastrointestinal disorders abdominal pain, constipation, diarrhoea, flatulence, nausea/ vomiting, fundic gland polyps (benign)
Croatian: Poremećaji probavnog sustava bol u abdomenu, konstipacija, proljev, flatulencija, mučnina/ povraćanje, polipi fundusnih žlijezda želuca (dobroćudni)
English: General disorders and administration site disorders malaise, increased sweating
Croatian: Opći poremećaji i reakcije na mjestu primjene malaksalost, pojačano znojenje
English: • Citalopram, imipramine or clomipramine (used to treat depression).
Croatian: • Citalopram, imipramin ili klomipramin (koriste se za liječenje depresije).
English: • Methotrexate (used to treat cancer and rheumatic disorders)
Croatian: • Metotreksat (koristi se za liječenje raka i reumatskih bolesti)
English: The pellets should not be chewed or crushed.
Croatian: Pelete se ne smiju žvakati niti drobiti.
English: Treatment with omeprazole 40 mg once a day had no effect on the exposure of lopinavir (with concomitant ritonavir).
Croatian: Liječenje omeprazolom u dozi od 40 mg jedanput na dan nije utjecalo na izloženost lopinaviru (primijenjenim zajedno s ritonavirom).
English: Esomeprazole is a CYP2C19 inhibitor.
Croatian: Esomeprazol je inhibitor CYP2C19.
English: The secondary endpoint of complete resolution of heartburn, defined as no heartburn on the patient's diary card for 7 consecutive days, was statistically significant at both week 1 (10.0% - 15.2% vs placebo 0.9% - 2.4%, p = 0.014, p<0.001) and week 2 (25.2% - 35.7% vs placebo 3.4% - 9.0%, p<0.001).
Croatian: Sekundarna mjera ishoda potpunog povlačenja žgaravice definirana kao izostanak žgaravice na bolesnikovoj kartici tijekom posljednjih 7 uzastopnih dana bila je statistički značajna i u 1. tjednu (10,0% do 15,2% u odnosu na 0,9%-2,4% u bolesnika koji su primali placebo, p=0,014, p<0,001) i u 2. tjednu (25,2%35,7% u odnosu na 3,4%-9,0% u bolesnika koji su primali placebo, p <0,001).
English: The normal symptoms of reflux are a painful sensation in the chest rising up to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
Croatian: Simptomi refluksa mogu biti osjećaj boli u prsnom košu koji se diže do grla (žgaravica) te kiseli okus u ustima (povrat kiseline).
English: Nexium Control contains sucrose
Croatian: Nexium Control sadrži saharozu
English: Nexium Control 20 mg Capsules
Croatian: Nexium Control 20 mg kapsule