FrancophonIA/ELRC3.0 huggingface dataset:
English: The score line facilitates breaking of the tablet into 4 equal doses.
Croatian: Urez olakšava lomljenje tablete na 4 jednake doze.
English: Bed-wetting at night
Croatian: Noćno mokrenje u krevet
English: These symptoms may be due to parts of the intestine becoming paralysed.
Croatian: Ovi simptomi mogu biti posljedica paralize dijelova crijeva.
English: These adverse effects can be potentiated by the concomitant intake of alcohol.
Croatian: Te nuspojave mogu biti pojačane kod istodobnog uzimanja alkohola.
English: • sexual disturbances (decreased sex-drive, problems with erection)
Croatian: • seksualni poremećaji (smanjen seksualni nagon, tegobe s erekcijom)
English: Long-term safety data in children and adolescents concerning growth, maturation and cognitive and behavioural development are not available (see section 4.2).
Croatian: Nema dostupnih podataka o dugoročnoj sigurnosti primjene u djece i adolescenata u pogledu rasta, sazrijevanja i kognitivnog i bihevioralnog razvoja (vidjeti dio 4.2).
English: Usually the X is added to a solution for infusion.
Croatian: Obično se X dodaje u otopinu za infuziju.
English: Do not use this medicine after the expiry date which is stated on the label afterr EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na naljepnici iza oznake EXP.
English: Therefore, amitriptyline may increase the risk for cardiac arrhythmia (see section 4.4).
Croatian: Stoga amitriptilin može povećati rizik od srčanih aritmija (vidjeti dio 4.4).
English: The therapeutic plasma concentration in major depression is around 80 - 200 ng/ml (≈ 280 - 700 nmol/l) (for amitriptyline + nortriptyline).
Croatian: Terapijska koncentracija u plazmi kod velike depresije iznosi oko 80 - 200 ng/ml (≈ 280 - 700 nmol/l) (za amitriptilin + nortriptilin).
English: Any degree of heart block or disorders of cardiac rhythm and coronary artery insufficiency.
Croatian: Bilo koji stupanj srčanog bloka ili poremećaja srčanog ritma i koronarna insuficijencija.
English: Anaesthetics given during tri/tetracyclic antidepressant therapy may increase the risk of arrhythmias and hypotension.
Croatian: Anestetici koji se daju tijekom terapije tricikličkim/tetracikličkim antidepresivima mogu povećati rizik od aritmija i hipotenzije.
English: Steady state plasma levels of amitriptyline + nortriptyline are reached within a week for most patients, and in steady state the plasma level comprises approximately equal parts of amitriptyline and nortriptyline around the clock following treatment with conventional tablets 3 times a day.
Croatian: U većine bolesnika, razine amitriptilina i nortriptilina u plazmi postižu stanje dinamičke ravnoteže unutar tjedan dana, a u stanju dinamičke ravnoteže razina u plazmi sastoji se od približno jednakih udjela amitriptilina i nortriptilina tijekom 24 sata nakon liječenja konvencionalnim tabletama 3 puta na dan.
English: The genotoxic potential of amitriptyline has been investigated in various in vitro and in vivo studies.
Croatian: Genotoksičnost amitriptilina istražena je u raznim in vitro i in vivo ispitivanjima.
English: • if you are taking medicines known as monoamine oxidase inhibitors (MAOIs)
Croatian: • ako uzimate lijekove koji se nazivaju inhibitori monoaminooksidaze (MAOi)
English: Do not use this medicine after the expiry date which is stated on the card box and ampoule.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kartonskoj kutiji i ampuli.
English: The solution for infusion prepared with sodium chloride solution 0.9% must be used immediately.
Croatian: Otopina za infuziju pripremljena s 0,9 %-tnom otopinom natrijevog klorida mora se odmah primijeniti.
English: X contains lactose
Croatian: X sadrži laktozu
English: • low blood pressure, weak pulse, pallor
Croatian: • nizak krvni tlak, slab puls, bljedilo
English: Your doctor may take blood samples to determine the level of amitriptyline in the blood (see also section 2).
Croatian: Liječnik može uzeti uzorke krvi kako bi odredio razinu amitriptilina u krvi (pogledajte također dio 2).
English: Heart failure, hypotension, cardiogenic shock.
Croatian: Zatajenje srca, hipotenzija, kardiogeni šok.
English: Your doctor may take blood samples to determine the level this medicine in the blood (see also section 2).
Croatian: Liječnik može uzeti uzorke krvi kako bi odredio razinu ovog lijeka u krvi (pogledajte također dio 2).
English: Monitor for rhabdomyolysis if the patient has been unconscious for a considerable time.
Croatian: Pratiti moguću pojavu rabdomiolize ako je bolesnik bez svijesti dulje vrijeme.
English: • epilepsy, a history of convulsions or fits
Croatian: • epilepsiju, konvulzije ili napadaje u povijesti bolesti
English: Elderly patients over 65 years of age:
Croatian: Stariji bolesnici u dobi iznad 65 godina
English: Known poor metabolisers of CYP2D6 or CYP2C19
Croatian: Poznati slabi metabolizatori CYP2D6 ili CYP2C19
English: If necessary the dose can be increased by 25 mg or 50 mg after 1 week up to 150 mg daily.
Croatian: Po potrebi se doza može povisiti za 25 mg ili 50 mg nakon 1 tjedna do najviše 150 mg na dan.
English: Cardiac symptoms: Arrhythmias (ventricular tachyarrhythmias, torsade de pointes, ventricular fibrillation).
Croatian: Srčani simptomi: aritmije (ventrikularne tahiaritmije, torsade de pointes, ventrikularna fibrilacija).
English: A single dose above 75 mg is not recommended.
Croatian: Ne preporučuje se uzimati jednokratnu dozu višu od 75 mg.
English: If you have thoughts of harming or killing yourself at any time, contact your doctor or go to a hospital straight away.
Croatian: Ako u bilo kojem trenutku počnete razmišljati o samoozljeđivanju ili samoubojstvu, odmah se obratite liječniku ili otiđite u bolnicu.
English: • This medicines should not be taking at the same time as an anticholinergic drug (see also section 2 Other medicines and X)
Croatian: • Ovaj se lijek ne smije uzimati istovremeno s antikolinergičkim lijekom (vidjeti također dio 2 Drugi lijekovi i X).
English: Prolonged QT interval
Croatian: Produljeni QT interval
English: Episodes of mania
Croatian: Manične epizode
English: If you are going to have an operation and receive general or local anaesthetics, you should tell your doctor that you are taking this medicine.
Croatian: Ako se spremate na kirurški zahvat i primit ćete opće ili lokalne anestetike, trebate obavijestiti liječnika da uzimate ovaj lijek.
English: Great care is necessary if amitriptyline is administered to hyperthyroid patients or to those receiving thyroid medication, since cardiac arrhythmias may develop.
Croatian: Potreban je veliki oprez ako se amitriptilin primjenjuje bolesnicima s hipertireozom ili onima koji primaju lijekove za štitnjaču jer se mogu razviti srčane aritmije.
English: Reduced liver function Careful dosing and, if possible, a serum level determination is advisable.
Croatian: Savjetuje se pažljivo doziranje i, po mogućnosti, određivanje razine u serumu.
English: Simultaneous administration of amitriptyline and MAOIs may cause serotonin syndrome (a combination of symptoms, possibly including agitation, confusion, tremor, myoclonus and hyperthermia).
Croatian: Istodobna primjena amitriptilina i MAO inhibitora može uzrokovati serotoninski sindrom (kombinacija simptoma, koja može uključivati agitaciju, konfuziju, tremor, mioklonus i hipertermiju).
English: In the presence of ethanol amitriptyline free plasma concentrations and nortriptyline concentrations were increased.
Croatian: U prisutnosti etanola koncentracije slobodnog amitriptilina u plazmi i koncentracije nortriptilina bile su povišene.
English: Saroten and associated names is indicated for in-hospital treatment of major depressive disorders in adults.
Croatian: Saroten i pridružena imena je indiciran za bolničko liječenje velikog depresivnog poremećaja u odraslih.
English: Duration of treatment Do not change the dose of the medicine or stop taking the medicine without consulting your doctor first.
Croatian: Nemojte promijeniti dozu lijeka ili prestati uzimati lijek a da se prethodno niste savjetovali s liječnikom.
English: Concomitant treatment with MAOIs (monoamine oxidase inhibitors) is contra-indicated (see section 4.5).
Croatian: Istodobno liječenje MAO inhibitorima (inhibitorima monoaminooksidaze) je kontraindicirano (vidjeti dio 4.5).
English: • cisapride (used to treat certain types of indigestion)
Croatian: • cisaprid (primjenjuje se za liječenje određenih vrsta probavnih tegoba)
English: Depending on individual patient response, a lower dose of amitriptyline should be considered if a strong CYP2D6 inhibitor (e.g. bupropion, quinidine, fluoxetine, paroxetine) is added to amitriptyline treatment (see section 4.5).
Croatian: Ovisno o odgovoru pojedinog bolesnika, potrebno je razmotriti nižu dozu amitriptilina ako se liječenju amitriptilinom dodaje jaki inhibitor CYP2D6 (npr. bupropion, kinidin, fluoksetin, paroksetin) (vidjeti dio 4.5).
English: Carton/Label
Croatian: Kutija/naljepnica
English: In nursing mothers amitriptyline and nortriptyline are excreted in small amounts with the breast milk.
Croatian: U dojilja se amitriptilin i nortriptilin izlučuju u maloj količini u majčino mlijeko.
English: • congested nose.
Croatian: • začepljen nos.
English: Saroten injectable solution is used in hospitalized patients especially for the initial treatment of depressive disorders.
Croatian: Saroten otopina za injekciju primjenjuje se u hospitaliziranih bolesnika, osobito za početno liječenje depresivnih poremećaja.
English: • Depression in adults (major depressive episodes)
Croatian: • liječenje depresije u odraslih (velikih depresivnih epizoda)
English: Treatment with amitriptyline may be instituted 14 days after discontinuation of irreversible non-selective MAOIs and minimum one day after discontinuation of the reversible moclobemide.
Croatian: Liječenje amitriptilinom može se uvesti 14 dana nakon prestanka primjene ireverzibilnih neselektivnih MAO inhibitora i najmanje jedan dan nakon prestanka primjene reverzibilnog moklobemida.
English: • have a surgery planned as it might be necessary to stop the treatment with amitriptyline before you are given anaesthetics.
Croatian: • imate planiran kirurški zahvat, jer može biti potrebno prekinuti liječenje amitriptilinom prije nego što dobijete anestetike.
English: • numbness or tingling in the arms or legs
Croatian: • utrnulost ili trnci u rukama i nogama
English: The elimination half-life (t½ β) amitriptyline after peroral administration is about 25 hours (24.65±6.31 hours; range 16.49-40.36 hours).
Croatian: Poluvijek eliminacije (t½ β) amitriptilina nakon peroralne primjene iznosi oko 25 sati (24,65 ± 6,31 sati; raspon 16,49 - 40,36 sati).
English: Intravenous infusion
Croatian: Intravenska infuzija
English: Electrolyte disturbances (hypokalaemia, hyperkalaemia, hypomagnesaemia) are known to be conditions increasing the proarrythmic risk.
Croatian: Poznato je da su poremećaji elektrolita (hipokalemija, hiperkalemija, hipomagnezemija) stanja koja povećavaju proaritmijski rizik.
English: Deaths by deliberate or accidental overdosage have occurred with this class of medicament.
Croatian: S ovom skupinom lijekova bilo je smrtnih slučajeva namjernim ili slučajnim predoziranjem.
English: What you need to know before you take X
Croatian: Što morate znati prije nego što primite X
English: Dose to be administered 1-1½ hours before bedtime.
Croatian: Doza se primjenjuje 1 - 1½ sat prije odlaska na spavanje.
English: • narrow angle glaucoma (loss of vision due to abnormally high pressure in the eye)
Croatian: • glaukom uskog kuta (gubitak vida zbog abnormalno visokog tlaka u oku)
English: It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals.
Croatian: Sprječava ponovnu pohranu, te posljedično inaktivaciju noradrenalina i serotonina na živčanim završecima.
English: Antifungals such as fluconazole and terbinafine increase serum concentrations of tricyclics and accompanying toxicity.
Croatian: Antimikotici kao što su flukonazol i terbinafin povećavaju koncentracije tricikličkih antidepresiva u serumu i popratnu toksičnost.
English: • particular forms of abnormal heart rhythm (so called torsades de pointes)
Croatian: • posebni oblici nepravilnog srčanog ritma (takozvani torsades de pointes)
English: This medicine is used to treat:
Croatian: Ovaj se lijek primjenjuje za:
English: Do not give this medicine to children and adolescents aged below 18 years for these treatments, as safety and efficacy have not been established in this age group.
Croatian: Nemojte davati ovaj lijek djeci i adolescentima mlađima od 18 godina za liječenje ovih tegoba s obzirom na to da sigurnost i djelotvornost nisu ustanovljene u ovoj dobnoj skupini.
English: • medicines for certain heart conditions (e.g. beta blockers and antiarrhythmics)
Croatian: • lijekovi za određene srčane bolesti (npr. beta blokatori i antiaritmici)
English: As described for other psychotropics, amitriptyline may modify insulin and glucose responses calling for adjustment of the antidiabetic therapy in diabetic patients; in addition the depressive illness itself may affect patients' glucose balance.
Croatian: Kako se navodi i za druge psihotropne lijekove, amitriptilin može promijeniti inzulinski i glikemijski odgovor, što zahtijeva prilagodbu antidijabetičke terapije u bolesnika s dijabetesom; uz to, sama depresija može utjecati na ravnotežu glukoze u bolesnika.
English: Disturbance in attention, dysgeusia.
Croatian: često poremećaj pozornosti, disgeuzija, parestezija,
English: Examples of strong CYP2D6 inhibitors include bupropion, fluoxetine, paroxetine and quinidine.
Croatian: Primjeri jakih inhibitora CYP2D6 uključuju bupropion, fluoksetin, paroksetin i kinidin.
English: • allergic inflammation of the lung alveoli and of the lung tissue.
Croatian: • alergijska upala plućnih alveola i plućnog tkiva.
English: Prophylactic treatment of chronic tension type headache and prophylactic treatment of migraine in adults Treatment must be continued for an appropriate length of time.
Croatian: Profilaktičko liječenje kronične tenzijske glavobolje i profilaktičko liječenje migrene u odraslih Liječenje se mora provoditi tijekom odgovarajuće dugog razdoblja.
English: • astemizole and terfenadine (used to treat allergies and hayfever)
Croatian: • astemizol i terfenadin (primjenjuju se za liječenje alergija i peludne groznice)
English: • diabetes as you might need and adjustment of your antidiabetic medicine.
Croatian: • šećernu bolest, jer će Vam možda trebati prilagoditi antidijabetički lijek.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from the therapy of this medicinal product taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Croatian: Potrebno je odlučiti da li prekinuti dojenje ili prekinuti liječenje/suzdržati se od liječenja ovim lijekom uzimajući u obzir korist dojenja za dijete i korist liječenja za ženu.
English: Clinically relevant interactions may be expected with concomitant use of amitriptyline and strong CYP3A4 inhibitors such as ketoconazole, itraconazole and ritonavir.
Croatian: Klinički važne interakcije mogu se očekivati kod istovremene primjene amitriptilina i jakih inhibitora CYP3A4, kao što su ketokonazol, itrakonazol i ritonavir.
English: Take Use caution when using amitriptyline and methadone concomitantly due to a potential for additive effects on the QT interval and increased risk of serious cardiovascular effects.
Croatian: Budite oprezni kad istodobno primjenjujete amitriptilin i metadon zbog mogućih aditivnih učinaka na QT interval i povećan rizik od ozbiljnih kardiovaskularnih učinaka.
English: • absent sensation of appetite
Croatian: • odsustvo osjećaja gladi
English: Amitriptyline may induce side effects similar to other tricyclic antidepressants.
Croatian: Amitriptilin može izazvati nuspojave slične drugim tricikličkim antidepresivima.
English: • blue discolouration of the skin
Croatian: • plavičastu boju kože
English: The excretion proceeds mainly with urine.
Croatian: Izlučivanje se uglavnom odvija putem mokraće.
English: This medical product should be used with caution in patients with convulsive disorders, urinary retention, prostatic hypertrophy, hyperthyroidism, paranoid symptomatology and advanced hepatic or cardiovascular disease, pylorus stenosis and paralytic ileus.
Croatian: Ovaj je lijek potrebno primjenjivati s oprezom u bolesnika s konvulzivnim poremećajima, urinarnom retencijom, hipertrofijom prostate, hipertireozom, paranoidnom simptomatologijom i uznapredovalom jetrenom i kardiovaskularnom bolešću, stenozom pilorusa i paralitičkim ileusom.
English: Adrenergic neurone blockers: Tricyclic antidepressants may counteract the antihypertensive effects of centrally acting antihypertensives such as guanethidine, betanidine, reserpine, clonidine and methyldopa.
Croatian: Blokatori adrenergičkih neurona: Triciklički antidepresivi mogu poništiti antihipertenzivne učinke antihipertenziva s centralnim djelovanjem kao što su gvanetidin, betanidin, rezerpin, klonidin i metildopa.
English: The tablets should be swallowed with water independent of meals.>
Croatian: Tablete se trebaju progutati s vodom, neovisno o obrocima.>
English: The antidepressant effect usually sets in after 2 - 4 weeks.
Croatian: Antidepresivni učinak obično nastupa nakon 2 - 4 tjedna.
English: The estimated daily infant exposure (amitriptyline + nortriptyline) averages 2% of the corresponding maternal weight related doses of amitriptyline (in mg/kg) (see section 4.6).
Croatian: Procijenjena dnevna izloženost dojenčeta (amitriptilinu + nortriptilinu) prosječno odgovara 2 % odgovarajuće doze amitripilina po kilogramu tjelesne težine u majke (u mg/kg) (vidjeti dio 4.6).
English: After about 1 to 2 weeks a stepwise reduction together with a change to the oral formulations for further treatment can be initiated.
Croatian: Nakon približno 1 do 2 tjedna može se započeti s postupnim sniženjem zajedno s prelaskom na oralne formulacije za daljnje liječenje.
English: • acute increase of pressure in the eye
Croatian: • akutno povišenje tlaka u oku
English: The mean absolute oral bioavailability is 53% (Fabs = 0.527±0.123; range 0.219-0.756).
Croatian: Srednja vrijednost apsolutne oralne bioraspoloživosti iznosi 53 % (Fabs = 0,527 ± 0,123; raspon 0,219 - 0,756).
English: • skin rash, nettle rash (urticarial), swelling of the face and tongue
Croatian: • kožni osip, koprivnjača (urtikarija), oticanje lica i jezika
English: • various cardiac symptoms such as heart block, heart failure, hypotension, cardiogenic shock,
Croatian: • razne srčane simptome kao što su srčani blok, zatajenje srca, hipotenzija, kardiogeni šok,
English: • medicines used to treat some mental illnesses (e.g. pimozide and sertindole)
Croatian: • lijekovi za liječenje nekih mentalnih bolesti (npr. pimozid i sertindol)
English: Convulsions.
Croatian: Konvulzije.
English: • Anticholinergic drugs such as certain medicines to treat Parkinsons disease and gastrointerstinal disorders (e.g. atropine, hyoscyamine)
Croatian: • antikolinergički lijekovi kao što su određeni lijekovi za liječenje Parkinsonove bolesti i gastrointestinalnih poremećaja (npr. atropin, hiosciamin)
English: These patients may have higher plasma concentrations of amitriptyline and its active metabolite nortriptyline.
Croatian: Ovi bolesnici mogu imati veće koncentracije amitriptilina i njegovog aktivnog metabolita nortriptilina u plazmi.
English: • Major Depressive Disorder
Croatian: • veliki depresivni poremećaj
English: The ratio milk concentration/serum concentration in women is around 1:1.
Croatian: Omjer koncentracije u mlijeku/ koncentracija u serumu u žena je oko 1:1.
English: Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, such as: monoamine oxidase inhibitors (MAOIs) e.g. phenelzine, iproniazid, isocarboxazid, nialamide or tranylcypromine (used to treat depression) or selegiline (used to treat Parkinson's disease).
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzeli bilo koje druge lijekove, kao što su: • inhibitori monoaminooksidaze (MAO), npr. fenelzin, iproniazid, izokarboksazid, nialamid ili tranilcipromin (primjenjuju se za liječenje depresije) ili selegilin (primjenjuje se za liječenje
English: Amitriptyline should not be used in children and adolescents aged less than 18 years, as safety and efficacy have not been established (see section 4.4).
Croatian: Amitriptilin se ne smije koristiti u djece i adolescenata u dobi ispod 18 godina, s obzirom na to da sigurnost i djelotvornost nisu ustanovljene (vidjeti dio 4.4).
English: Patients should be individually titrated to the dose that provides adequate analgesia with tolerable adverse drug reactions.
Croatian: Dozu je potrebno titrirati u svakog bolesnika posebno do one doze koja osigurava odgovarajuću analgeziju uz podnošljive nuspojave.
English: The CYP3A4 and CYP1A2 isozymes metabolise amitriptyline to a lesser extent.
Croatian: Izoenzimi CYP3A4 i CYP1A2 metaboliziraju amitriptilin u manjem opsegu.
English: The daily dose may be increased up to 100 mg - 150 mg, depending on individual patient response and tolerability.
Croatian: Dnevna doza može se povisiti na 100 mg - 150 mg, ovisno o odgovoru pojedinog bolesnika i podnošljivosti.
English: Tramadol: Concomitant use of tramadol (a CYP2D6 substrate) and tricyclic antidepressants (TCAs), such as amitriptyline increases the risk for seizures and serotonin syndrome.
Croatian: Tramadol: Istodobna primjena tramadola (supstrat CYP2D6) i tricikličkih antidepresiva kao što je amitriptilin povećava rizik od napadaja i serotoninskog sindroma.
English: • methadone (used to treat pain and for detoxification)
Croatian: • metadon (primjenjuje se za liječenje boli i za detoksifikaciju)
English: Do not drive or work with tools or machinery if you are affected.
Croatian: Vas, nemojte upravljati vozilima niti raditi s alatima ili strojevima.
English: Fever.
Croatian: Vrućica.
English: CYP2D6 inhibitors: The CYP2D6 isozyme can be inhibited by a variety of drugs, e.g. neuroleptics, serotonin reuptake inhibitors, beta blockers, and antiarrhythmics.
Croatian: Inhibitori CYP2D6: Izoenzim CYP2D6 mogu inhibirati razni lijekovi, npr., neuroleptici, inhibitori ponovne pohrane serotonina, beta blokatori i antiaritmici.
English: Severe liver disease.
Croatian: Teška bolest jetre.
English: Demethylnortriptyline and amitriptyline-N-oxide are only present in plasma in minute amounts; the latter is almost inactive.
Croatian: Demetilnortriptilin i amitriptilin-N-oksid prisutni su u plazmi samo u minimalnoj količini; ovaj drugi je gotovo nedjelatan.
English: • adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine (these may be present in cough or cold medicine, and in some anaesthetics)
Croatian: • adrenalin, efedrin, izoprenalin, noradrenalin, fenilefrin i fenilpropanolamin (mogu biti prisutni u lijekovima protiv kašlja ili prehlade i u nekim anesteticima)
English: Your doctor will advise you whether to start/continue/stop breast-feeding, or stop using this medicine taking into account the benefit of breast-feeding for your child and the benefit of therapy for you.
Croatian: Liječnik će Vam savjetovati da li započeti/nastaviti/prekinuti dojenje ili prekinuti uzimanje ovog lijeka uzimajući u obzir korist dojenja za Vaše dijete i korist liječenja za Vas.
English: Caution is also advised for co-administration of amitriptyline and diuretics inducing hypokalaemia (e.g. furosemide)
Croatian: Savjetuje se oprez i kod istovremene primjene amitriptilina i diuretika koji izazivaju hipokalemiju (npr. furosemid).
English: The analgesic effect is normally seen after 2 - 4 weeks of dosing.
Croatian: Analgetski učinak obično se opaža nakon 2 - 4 tjedna doziranja.
English: Very rare (<1/10,000);
Croatian: Vrlo rijetko (<1/10 000);
English: Initially 25 mg 2 times daily (50 mg daily).
Croatian: U početku, 25 mg dvaput na dan (50 mg na dan).