FrancophonIA/ELRC3.0 huggingface dataset:
English: Maximum daily dose is 3000 mg.
Danish: Den maksimale daglige dosis er 3.000 mg.
English: Sitagliptin 100 mg once daily added to ongoing metformin therapy (N=453)
Danish: Sitagliptin 100 mg en gang dagligt som supplement til metforminbehandling (N=453)
English: EU/1/10/620/009 14 film-coated tablets EU/1/10/620/010 28 film-coated tablets EU/1/10/620/011 56 film-coated tablets EU/1/10/620/021 60 film-coated tablets EU/1/10/620/012 112 film-coated tablets EU/1/10/620/013 168 film-coated tablets EU/1/10/620/022 180 film-coated tablets EU/1/10/620/014 196 film-coated tablets EU/1/10/620/015 50 x 1 film-coated tablets EU/1/10/620/016 196 (2 x 98) film-coated tablets EU/1/10/620/018 168 (2 x 84) film-coated tablets
Danish: EU/1/10/620/009 14 filmovertrukne tabletter EU/1/10/620/010 28 filmovertrukne tabletter EU/1/10/620/011 56 filmovertrukne tabletter EU/1/10/620/021 60 filmovertrukne tabletter EU/1/10/620/012 112 filmovertrukne tabletter EU/1/10/620/013 168 filmovertrukne tabletter EU/1/10/620/022 180 filmovertrukne tabletter EU/1/10/620/014 196 filmovertrukne tabletter EU/1/10/620/015 50 x 1 filmovertrukne tabletter EU/1/10/620/016 196 (2 x 98) filmovertrukne tabletter EU/1/10/620/018 168 (2 x 84) filmovertrukne tabletter
English: Maximum daily dose is 2000 mg.
Danish: Den maksimale daglige dosis er 2.000 mg.
English: - This medicine has been prescribed for you only.
Danish: - Lægen har ordineret Ristfor til Dem personligt.
English: Sitagliptin 50 mg + metformin 500 mg (N=183)
Danish: : Sitagliptin 50 mg + metformin 500 mg (N=183) Initialbehandling (to gange dagligt)
English: EU/1/10/620/001 14 film-coated tablets EU/1/10/620/002 28 film-coated tablets EU/1/10/620/003 56 film-coated tablets EU/1/10/620/019 60 film-coated tablets EU/1/10/620/004 112 film-coated tablets EU/1/10/620/005 168 film-coated tablets EU/1/10/620/020 180 film-coated tablets EU/1/10/620/006 196 film-coated tablets EU/1/10/620/007 50 x 1 film-coated tablets EU/1/10/620/008 196 (2 x 98) film-coated tablets EU/1/10/620/017 168 (2 x 84) film-coated tablets
Danish: EU/1/10/620/001 14 filmovertrukne tabletter EU/1/10/620/002 28 filmovertrukne tabletter EU/1/10/620/003 56 filmovertrukne tabletter EU/1/10/620/019 60 filmovertrukne tabletter EU/1/10/620/004 112 filmovertrukne tabletter EU/1/10/620/005 168 filmovertrukne tabletter EU/1/10/620/020 180 filmovertrukne tabletter EU/1/10/620/006 196 filmovertrukne tabletter EU/1/10/620/007 50 x 1 filmovertrukne tabletter EU/1/10/620/008 196 (2 x 98) filmovertrukne tabletter EU/1/10/620/017 168 (2 x 84) filmovertrukne tabletter
English: Maximum daily dose is 1000 mg.
Danish: Den maksimale daglige dosis er 1.000 mg.
English: depending on how your kidneys are working - if you have recently had a heart attack or have severe circulatory problems, such as ‘shock' or breathing difficulties - if you have liver problems - if you drink alcohol to excess (either every day or only from time to time) - if you are breast-feeding.
Danish: - Hvis De for nylig har haft et hjerteanfald eller har alvorlige kredsløbsproblemer, herunder shock eller vejrtrækningsbesvær.
English: In clinical studies, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, warfarin, or oral contraceptives, providing in vivo evidence of a low propensity for causing interactions with substrates of CYP3A4, CYP2C8, CYP2C9, and organic cationic transporter (OCT).
Danish: I kliniske undersøgelser ændrede sitagliptin ikke farmakokinetikken for metformin, glyburid, simvastatin, rosiglitazon, warfarin eller orale kontraceptiva betydeligt.
English: Least squares mean adjusted for insulin use at Visit 1 (pre-mixed vs. non-pre-mixed [intermediate- or long-acting]), and baseline value.
Danish: HbA1c (%) i 24. uge HbA1c (%) i 26. uge Gennemsnit beregnet ved mindste kvadraters metode justeret for anvendelse af insulin ved besøg 1 (forblandet versus ikkeforblandet [middellangtidsvirkende eller langtidsvirkende]) og baseline-værdi.
English: This is sometimes called insulin-dependent diabetes - if you have or have had an allergic reaction to sitagliptin, metformin, or Ristfor (see section 4) - if you are taking a sulphonylurea or insulin, diabetes medicines, together with Ristfor, as you may experience low blood sugar levels (hypoglycaemia).
Danish: - Hvis De tager anden diabetesmedicin, sulfonylurinstof eller insulin, sammen med Ristfor, da De så kan opleve lavt blodsukker (hypoglykæmi).
English: If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Danish: Er De i tvivl, så spørg lægen eller apotekspersonalet.
English: Placebo-corrected mean change in HbA1c (%) (95 % CI)
Danish: Placebokorrigeret gennemsnitlig ændring i HbA1c
English: What Ristfor looks like and contents of the pack
Danish: Udseende og pakningsstørrelser
English: If you take more Ristfor than you should
Danish: Hvis De har taget for meget Ristfor
English: Do not take Ristfor: - if you are allergic to sitagliptin or metformin or any of the other ingredients of this medicine (listed in section 6) - if you have severely reduced kidney function - if you have uncontrolled diabetes, with e.g. severe hyperglycaemia (high blood glucose), nausea, vomiting, diarrhoea, rapid weight loss, lactic acidosis (see “Risk of lactic acidosis” below) or ketoacidosis.
Danish: - Hvis De har dårligt kontrolleret diabetes, der eksempelvis er ledsaget af alvorlig hyperglykæmi (højt blodsukker), kvalme, opkastning, diarré, hurtigt vægttab, laktacidose (se ”Risiko for laktacidose” nedenfor) eller ketoacidose.
English: In a pre-/post-natal development study performed in rats sitagliptin showed no adverse effects.
Danish: Sitagliptin viste ingen bivirkninger i en præ- og postnatal udviklingsundersøgelse udført med rotter.
English: If any of the above apply to you, talk to your doctor for further instructions.
Danish: Kontakt lægen for at få yderligere vejledning, hvis noget af ovennævnte gælder for Dem.
English: Some patients taking metformin have experienced the following side effects after starting sitagliptin: Common (may affect up to 1 in 10 people): low blood sugar, nausea, flatulence, vomiting Uncommon (may affect up to 1 in 100 people): stomach ache, diarrhoea, constipation, drowsiness
Danish: Ikke almindelige (kan berøre op til 1 ud af 100 behandlede): Mavesmerter, diarré, forstoppelse, lavt blodsukker, døsighed.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate equivalent to 50 mg of sitagliptin and 1,000 mg of metformin hydrochloride.
Danish: Hver filmovertrukken tablet (tablet) indeholder sitagliptinphosphatmonohydrat svarende til 50 mg sitagliptin og 1.000 mg metforminhydrochlorid.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate equivalent to 50 mg of sitagliptin and 850 mg of metformin hydrochloride.
Danish: Hver filmovertrukken tablet (tablet) indeholder sitagliptinphosphatmonohydrat svarende til 50 mg sitagliptin og 850 mg metforminhydrochlorid.
English: Film coating poly(vinyl alcohol) macrogol 3350 talc (E553b) titanium dioxide (E171) iron oxide red (E172) iron oxide black (E172)
Danish: Talcum (E553b) Titandioxid (E171) Rød jernoxid (E172) Sort jernoxid (E172)
English: Each tablet contains sitagliptin phosphate monohydrate equivalent to 50 mg of sitagliptin and 850 mg of metformin hydrochloride.
Danish: Hver tablet indeholder sitagliptinphosphatmonohydrat svarende til 50 mg sitagliptin og 850 mg metforminhydrochlorid.
English: For patients inadequately controlled on dual combination therapy with the maximal tolerated dose of metformin and a sulphonylurea
Danish: Til patienter, der ikke er tilstrækkeligt kontrolleret på maksimal tolereret dosis af metforminmonoterapi
English: Each tablet contains sitagliptin phosphate monohydrate equivalent to 50 mg of sitagliptin and 1,000 mg of metformin hydrochloride.
Danish: Hver tablet indeholder sitagliptinphosphatmonohydrat svarende til 50 mg sitagliptin og 1.000 mg metforminhydrochlorid.
English: Ristfor 50 mg/1,000 mg film-coated tablets sitagliptin/metformin hydrochloride
Danish: Ristfor 50 mg/1.000 mg filmovertrukne tabletter sitagliptin/metforminhydrochlorid
English: What Ristfor is and what it is used for What you need to know before you take Ristfor How to take Ristfor
Danish: Det skal De vide, før De begynder at tage Ristfor Sådan skal De tage Ristfor Bivirkninger
English: Ristfor 50 mg/850 mg film-coated tablets sitagliptin/metformin hydrochloride
Danish: Ristfor 50 mg/850 mg filmovertrukne tabletter Sitagliptin/metforminhydrochlorid
English: Ristfor 50 mg/850 mg tablets sitagliptin/metformin HCl
Danish: Ristfor 50 mg/850 mg tabletter sitagliptin/metforminhydrochlorid
English: Ristfor 50 mg/1,000 mg tablets sitagliptin/metformin HCl
Danish: Ristfor 50 mg/1000 mg tabletter sitagliptin/metforminhydrochlorid
English: Uncommon nausea
Danish: Bulløs pemfigoid
English: What Ristfor contains
Danish: Ristfor indeholder:
English: Common flatulence
Danish: Flatulens
English: Slovenská republika Merck Sharp & Dohme, s. r. o. Tel.: +421 2 58282010 dpoc_czechslovak@merck.com
Danish: Tel.: +421 2 58282010 dpoc_czechslovak@merck.com
English: tmax is between 3 and 8 hours.
Danish: tmax er mellem 3 og 8 timer.
English: Diagnosis should be made according to current guidelines.
Danish: Diagnosen skal stilles i henhold til gældende retningslinjer.
English: Your doctor will advise you.
Danish: Lægen vil rådgive Dem.
English: The volume of distribution is around 10 l/kg.
Danish: Distributionsvolumen er ca. 10 l/kg.
English: In general, the observed side effects are mild to moderate.
Danish: Generelt er de observerede bivirkninger milde til moderate.
English: Mon → Tue → Wed → Thu → Fri → Sat → Sun
Danish: Man → Tirs → Ons → Tors → Fre → Lør → Søn
English: In another case of a large overdose, the patient also survived and recovered.
Danish: I et andet tilfælde med stor overdosis overlevede patienten også og kom sig.
English: As a consequence, only limited data are available and patients with these conditions should be closely supervised.
Danish: Som et resultat heraf er der kun en begrænset mængde data til rådighed, og patienter med disse tilstande skal overvåges nøje.
English: The effects of barbiturates and neuroleptics may be reduced.
Danish: Effekten af barbiturater og neuroleptika kan blive reduceret.
English: The clinical relevance of these findings is unknown.
Danish: Den kliniske relevans af disse observationer er ukendt.
English: No specific antidote for intoxication or overdose is available.
Danish: Der findes ingen specifik modgift mod forgiftning eller overdosering.
English: There is a possible relationship between this accumulation and the vacuolisation observed in lungs.
Danish: Der er en mulig sammenhæng mellem denne akkumulation og den vakuolisation, der observeredes i lunger.
English: Week 1, 2, 3, 4 Day 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
Danish: Uge 1, 2, 3, 4 Dag 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
English: Not known (frequency cannot be estimated from the available data):
Danish: Ikke kendte (hyppigheden kan ikke fastsættes ud fra forhåndenværende data):
English: This effect was only observed at high doses in rodents.
Danish: Denne virkning blev kun observeret ved høje doser hos gnavere.
English: Memory loss in Alzheimer's disease is due to a disturbance of message signals in the brain.
Danish: Hukommelsestab ved Alzheimers sygdom skyldes en forstyrrelse af signalstoffer i hjernen.
English: The patient received symptomatic treatment and plasmapheresis.
Danish: Patienten fik symptomatisk behandling og plasmaferese.
English: Treatment should be initiated and supervised by a physician experienced in the diagnosis and treatment of Alzheimer's dementia.
Danish: Behandlingen bør iværksættes og overvåges af en læge med erfaring i diagnosticering og behandling af Alzheimers demens.
English: Memantine has an absolute bioavailability of approximately 100%.
Danish: Memantin har en absolut biotilgængelighed på ca. 100%.
English: EXP {MM/YYYY}
Danish: EXP {MM/ÅÅÅÅ}
English: About 45% of memantine is bound to plasma-proteins.
Danish: Omkring 45% af memantin bindes til plasmaproteiner.
English: SYSTEM ORGAN CLASS
Danish: SYSTEMORGANKLASSE
English: CARTON AND LABEL FOR BOTTLE
Danish: ÆSKE OG MÆRKAT TIL FLASKE
English: This effect is known from other active substances with cationic amphiphilic properties.
Danish: Denne virkning kendes fra andre aktive stoffer med kationiske amfifile egenskaber.
English: Due to the pharmacological effects and the mechanism of action of memantine the following interactions may occur:
Danish: På grund af den farmakologiske effekt af og virkningsmekanismen for memantin kan følgende interaktioner forekomme:
English: In the prospectively defined primary analysis statistical significance was not reached at the primary efficacy endpoint at week 24.
Danish: I den prospektivt definerede primære analyse opnåedes der ikke statistisk signifikans på det primære effektmål i uge 24.
English: Once daily
Danish: En gang dagligt
English: GENERAL CLASSIFICATION FOR SUPPLY 15.
Danish: GENEREL KLASSIFIKATION FOR UDLEVERING 15.
English: The solution should be taken with a little water.
Danish: Opløsningen skal tages med lidt vand.
English: Psychotic reactions2
Danish: Psykotiske reaktioner2
English: It modulates the effects of pathologically elevated tonic levels of glutamate that may lead to neuronal dysfunction.
Danish: Det modulerer virkningen af patologisk forhøjede toniske niveauer af glutamat, der kan medføre neuronal dysfunktion.
English: Oral solution 50 ml
Danish: Oral opløsning 50 ml
English: 2 Isolated cases reported in post-marketing experience.
Danish: 2 Enkeltstående tilfælde rapporteret efter markedsføringen.
English: Some factors that may raise urine pH (see section 5.2 “Elimination”) may necessitate careful monitoring of the patient.
Danish: Visse faktorer, der kan forhøje urin-pH (se under punkt 5.2), kan nødvendiggøre omhyggelig monitorering af patienten.
English: You may experience increased symptoms as described in section 4.
Danish: De kan opleve forøgede symptomer, som beskrevet i punkt 4 “Bivirkninger”.
English: In the event of overdose, treatment should be symptomatic.
Danish: I tilfælde af overdosering bør der anvendes symptomatisk behandling.
English: The tablets should be swallowed with some water.
Danish: Tabletterne bør synkes sammen med noget vand.
English: This dose will be increased weekly by 5 mg until the recommended (maintenance) dose is reached.
Danish: Denne dosis vil blive øget hver uge med 5 mg, indtil den anbefalede (vedligeholdelses-) dosis er nået.
English: 100 D-60318 Frankfurt/Main Germany
Danish: 100 D-60318 Frankfurt/Main Tyskland
English: Your doctor will tell you whether your illness allows you to drive and to use machines safely.
Danish: Deres læge vil give Dem besked på, om Deres sygdom tillader, at De uden risiko kan køre bil og betjene maskiner.
English: Date of first authorisation: 22 Nov 2012 Date of latest renewal: {DD month YYYY}
Danish: Dato for første markedsføringstilladelse: 22 november 2012 Dato for seneste genregistrering: {DD måned ÅÅÅÅ}
English: - Do not take a double dose to make up for a forgotten dose.
Danish: - de må ikke tage en dobbeltdosis som erstatning for den glemte dosis.
English: The treatment scheme is also indicated on the treatment initiation pack.
Danish: Behandlingsskemaet er også angivet på behandlingspakken.
English: As the effects have neither been observed in long term studies in rodents nor in non-rodents, the clinical relevance of these findings is unknown.
Danish: Da virkningerne hverken er blevet observeret i langtidsstudier hos gnavere eller hos ikke-gnavere, er den kliniske relevans af disse observationer ukendt.
English: In man, about 80% of the circulating memantine-related material is present as the parent compound.
Danish: Hos mennesket er ca. 80% af det cirkulerende memantin-relaterede materiale til stede som modersubstans.
English: Ataxia and other preclinical signs have preceded the vacuolisation and necrosis.
Danish: Ataksi og andre prækliniske tegn er indtruffet før vakuolisering og nekrose.
English: The tolerance and dosing of memantine should be reassessed on a regular basis, preferably within three months after start of treatment.
Danish: Tolerance og dosering af memantin bør regelmæssigt vurderes, helst senest tre måneder efter behandlingsstart.
English: • Concomitant use of memantine and amantadine should be avoided, owing to the risk of pharmacotoxic psychosis.
Danish: • Samtidig brug af memantin og amantadin skal undgås på grund af risikoen for farmakotoksisk psykose.
English: Drug hypersensitivity
Danish: Lægemiddelhypersensitivitet
English: Once opened, the contents of the bottle should be used within 3 months.
Danish: Når flasken er anbrudt, skal indholdet anvendes inden for 3 måneder.
English: Memantine is eliminated in a monoexponential manner with a terminal t½ of 60 to 100 hours.
Danish: Memantin har en monoeksponentiel elimination med en terminal t½ på 60 til 100 timer.
English: For detailed instructions on the preparation and handling of the product see end of this leaflet.
Danish: Detaljerede instruktioner i tilberedning og håndtering af produktet findes sidst i denne brochure.
English: Instruction for proper use of the pump
Danish: Vejledning i korrekt brug af pumpen
English: There is no indication that food influences the absorption of memantine.
Danish: Der er ikke noget der tyder på, at føde påvirker absorptionen af memantin.
English: Both compounds are chemically related NMDA-antagonists.
Danish: Begge forbindelser er kemisk beslægtede NMDA-antagonister.
English: Summary of safety profile
Danish: Opsummering af sikkerhedsprofil
English: Hold a glass with a little water or a spoon below the nozzle.
Danish: Hold et glas med lidt vand eller en ske under tudens åbning.
English: Hallucinations1
Danish: Hallucinationer1
English: The renal elimination rate of memantine under alkaline urine conditions may be reduced by a factor of 7 to 9 (see section 4.4).
Danish: Den renale eliminationsrate for memantin kan, under alkaliske urinforhold, reduceres med en faktor på 7 til 9 (se under punkt 4.4).
English: Thereafter, the clinical benefit of memantine and the patient's tolerance of treatment should be reassessed on a regular basis according to current clinical guidelines.
Danish: Herefter bør den behandlingsmæssige fordel af memantin og patientens tolerabilitet regelmæssigt vurderes i henhold til gældende kliniske retningslinjer.
English: Treatment of patients with moderate to severe Alzheimer's disease.
Danish: Behandling af patienter med moderat til svær Alzheimers sygdom.
English: Therapy should only be started if a caregiver is available who will regularly monitor the intake of the medicinal product by the patient.
Danish: Behandlingen bør kun påbegyndes, hvis patienten har en omsorgsperson til rådighed, som er villig til regelmæssigt at overvåge patientens lægemiddelindtagelse.
English: Memantine should not be used during pregnancy unless clearly necessary.
Danish: Memantin må ikke anvendes under graviditet, medmindre det er tvingende nødvendigt.
English: If the pump does not function as described during intended use and according to instruction, the patient should consult the treating physician or a pharmacist.
Danish: Hvis pumpen ved brug ikke virker som beskrevet og i henhold til anvisningen, skal patienten kontakte den behandlende læge eller apoteket.
English: 1 Hallucinations have mainly been observed in patients with severe Alzheimer´s disease.
Danish: 1 Hallucinationer er hovedsageligt observeret hos patienter med svær Alzheimers sygdom.
English: It is not known whether memantine is excreted in human breast milk but, taking into consideration the lipophilicity of the substance, this probably occurs.
Danish: Det vides ikke, om memantin udskilles i human modermælk, men i betragtning af stoffets lipofilicitet forventes dette at være tilfældet.
English: The same may be true for ketamine and dextromethorphan (see also section 4.4).
Danish: Det samme kan gøre sig gældende for ketamin og dextromethorphan (se også under pkt 4.4).
English: Animal studies indicate a potential for reducing intrauterine growth at exposure levels, which are identical or slightly higher than at human exposure (see section 5.3).
Danish: Dyrestudier antyder en potentiel mulighed for intrauterin væksthæmning ved eksponeringsniveauer, der er identiske med eller lidt højere end human eksponering (se under punkt 5.3).
English: Also, urine pH may be elevated by states of renal tubulary acidosis (RTA) or severe infections of the urinary tract with Proteus bacteria.
Danish: Urin-pH kan også forhøjes ved tilstande med renal tubulær acidose (RTA) eller alvorlige urinvejsinfektioner med Proteus bacteria.
English: There was no evidence of any carcinogenicity in life long studies in mice and rats.
Danish: Der var ingen tegn på karcinogenicitet i livstidsstudier på rotter og mus.
English: Maintenance treatment can be continued for as long as a therapeutic benefit is favourable and the patient tolerates treatment with memantine.
Danish: Vedligeholdelsesbehandling kan fortsætte, så længe der er terapeutiske fordele, og patienten kan tåle memantinbehandlingen.
English: 50 ml (and 10 x 50 ml) in brown glass bottles (Hydrolytic Class II) and 100 ml in brown glass bottles (Hydrolytic Class III).
Danish: 50 ml (og 10x 50 ml) i brune glasflasker (hydrolytisk klasse II) og 100 ml i brune glasflasker (hydrolytisk klasse III).
English: None of these metabolites exhibit NMDA-antagonistic activity.
Danish: Ingen af disse metabolitter udviser NMDA-antagonistisk aktivitet.
English: MARKETING AUTHORISATION NUMBER(S) 13.
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (NUMRE) 13.
English: Not known (frequency cannot be estimated from the available data): • Inflammation of the pancreas, inflammation of the liver (hepatitis) and psychotic reactions
Danish: Ikke kendte (hyppighed kan ikke estimeres ud fra forhåndenværende data): • Betændelse i bugspytkirtlen, leverbetændelse (hepatitis) og psykotiske reaktioner
English: There is one published case report on a possible risk also for the combination of memantine and phenytoin.
Danish: Der er publiceret en kasuistik, der også viser en mulig risiko ved kombination af memantin og phenytoin.
English: In rats, foetal growth reduction was noted at exposure levels, which are identical or slightly higher than at human exposure.
Danish: Hos rotter noteredes en føtal vækstreduktion ved eksponeringsniveauer, der var identiske med eller lidt højere end ved human eksponering.
English: If you have impaired kidney function, your doctor will decide upon a dose that suits your condition.
Danish: Hvis De har nedsat nyrefunktion, afgør Deres læge, hvilken dosis der passer til Deres tilstand.
English: Renal handling also involves tubular reabsorption, probably mediated by cation transport proteins.
Danish: Omsætningen i nyrerne involverer også tubulær reabsorption, der sandsynligvis medieres af katione transportproteiner.
English: In particular, Memantine Merz may change the effects of the following medicines and their dose may need to be adjusted by your doctor:
Danish: I særdeleshed kan Memantine Merz ændre virkningen af følgende medicin, og lægen kan derfor være nødt til at ændre doseringen:
English: Discontinuation of memantine should be considered when evidence of a therapeutic effect is no longer present or if the patient does not tolerate treatment.
Danish: Seponering bør overvejes, når der ikke længere er tegn på terapeutisk effekt, eller hvis patienten ikke kan tåle behandlingen.
English: In these situations the treatment should be carefully supervised, and the clinical benefit of Memantine Merz reassessed by your doctor on a regular basis.
Danish: I disse situationer bør behandlingen overvåges nøje, og den kliniske gavn af Memantine Merz skal regelmæssigt vurderes af Deres læge.