FrancophonIA/ELRC3.0 huggingface dataset:
English: Histamine H2-receptor antagonists and proton pump inhibitors Concomitant administration of fluvastatin with cimetidine, ranitidine or omeprazole results in an increase in the bioavailability of fluvastatin, which, however, is of no clinical relevance.
Danish: Histamin H2-receptorantagonister og protonpumpehæmmere Administration af fluvastatin samtidig med cimetidin, ranitidin eller omeprazol medfører en forøgelse i biotilgængeligheden af fluvastatin, som dog er uden klinisk betydning.
English: Section 5.3 - Preclinical safety data
Danish: Afsnit 5.3 - Prækliniske sikkerhedsdata
English: An analysis from the pooled clinical trial databases of Lescol IR or Lescol XL registration studies provided by the MAH showed that the likelihood of achieving LDL reductions of ≥25% was modest with a 20 mg daily dosage of fluvastatin.
Danish: En analyse på grundlag af de samlede databaser over kliniske undersøgelser af Lescol IR eller Lescol XL registreringsundersøgelser indsendt af indehaveren af markedsføringstilladelsen viste, at sandsynligheden for at opnå nedsættelser af LDL på ≥25 % var beskeden med en dosis fluvastatin på 20 mg om dagen.
English: Fluvastatin should be administered at least 4 hours after the resin (e.g. cholestyramine) to avoid a significant interaction due to drug binding of the resin.
Danish: Fluvastatin bør administreres mindst 4 timer efter resinet (fx colestyramin) for at undgå signifikant interaktion som følge af lægemidlets binding til resinet.
English: Concomitant administration of fluvastatin with the potent cytochrome P450 (CYP) 3A4 inhibitors itraconazole and erythromycin has minimal effects on the bioavailability of fluvastatin.
Danish: Samtidig administration af fluvastatin og de potente cytokrom P450-(CYP)3A4-hæmmere itraconazol og erythromycin har en minimal effekt på biotilgængeligheden af fluvastatin.
English: The risk of myopathy has been reported to be increased in patients receiving immunosuppressive agents (including ciclosporin), fibrates, nicotinic acid or erythromycin together with other HMG-CoA reductase inhibitors.
Danish: Ifølge rapporter er risikoen for myopati øget hos patienter, der tager immunsuppressive stoffer (inklusive ciclosporin), fibrater, nicotinsyre eller erythromycin sammen med HMG-CoAreduktasehæmmere.
English: The pharmacokinetics of fluvastatin remain unchanged in patients with mild to severe renal insufficiency.
Danish: Fluvastatins farmakokinetik forbliver uændret hos patienter med mildt til svær nyreinsufficiens.
English: United Kingdom Novartis Pharmaceuticals UK Ltd (Trading as Sandoz
Danish: Storbritannien Novartis Pharmaceuticals UK Ltd (Trading as Sandoz Pharmaceuticals) Frimley Business Park
English: Dose adjustments should be made at intervals of 4 weeks or more.'
Danish: Dosisjusteringer bør foretages med intervaller på fire uger eller mere."
English: The statement that isolated cases of myopathy have been reported post-marketing for concomitant administration of fluvastatin with ciclosporin and the statement related to concomitant administration of fluvastatin and colchicines has been included in the MAH's proposal and agreed by the CHMP.
Danish: Erklæringen om, at isolerede tilfælde af myopati er blevet indberettet efter markedsføringen ved samtidig administration af fluvastatin og ciclosporin og erklæringen vedrørende samtidig administration af fluvastatin og colchicin er medtaget i forslaget fra indehaveren af markedsføringstilladelsen og er godkendt af CHMP.
English: Given the minimal involvement of this enzyme in the metabolism of fluvastatin, it is expected that other CYP3A4 inhibitors (e.g. ketoconazole, ciclosporin) are unlikely to affect the bioavailability of fluvastatin.
Danish: Da dette enzym er meget lidt involveret i metabolismen af fluvastatin, forventes det for usandsynligt, at andre CYP3A4hæmmere (f.eks. ketoconazol og ciclosporin) har nogen effekt på biotilgængeligheden af fluvastatin.
English: In glibenclamide-treated NIDDM patients (n=32), administration of fluvastatin (40 mg twice daily for 14 days) increased the mean Cmax, AUC, and t½ of glibenclamide by approximately 50%, 69%, and 121%, respectively.
Danish: Hos glibenclamidbehandlede NIDDM-patienter (n=32) forøgede administration af fluvastatin (40 mg to gange dagligt i 14 dage) den gennemsnitlige Cmax, AUC og t½ for glibenclamid med henholdsvis ca. 50 %, 69 % og 121 %.
English: - if you have severe upper stomach pain (signs of inflamed pancreas).
Danish: - hvis du får stærke smerter øverst i maven (tegn på betændelse i bugspytkirtlen).
English: Section 4.3 - Contra-indications
Danish: Afsnit 4.3 - Kontraindikationer
English: In the LIPS study which was the basis for this indication, the 80 mg daily dose of fluvastatin (i.e., Lescol IR 40 mg BID) was used as starting dose.
Danish: I LIPSundersøgelsen, der dannede grundlag for denne indikation, blev en daglig dosis på 80 mg fluvastatin (dvs. Lescol IR 40 mg to gange daglig (BID)) anvendt som startdosis.
English: Bartók Béla út 43-47, 5th Floor, 1114 Budapest, Hungary
Danish: Novartis Hungária Kft. Pharma Bartók Béla út 43-47, 5th Floor 1114 Budapest
English: Doses should be individualised according to baseline LDL-C levels and the recommended goal of therapy to be accomplished.
Danish: Dosis bør tilpasses individuelt ud fra baselineniveau af LDL-C og det anbefalede behandlingsmål, der skal nås.
English: Therefore, Lescol/Lescol XL is contraindicated during pregnancy (see section 4.3).
Danish: Derfor er Lescol/Lescol XL kontraindiceret under graviditet (se pkt.
English: Immune system disorders Very rare:
Danish: Immunsystemet Meget sjælden:
English: − Your doctor can also prescribe Lescol/ Lescol XL to prevent further serious cardiac events (e.g. heart attack) in patients after they already went through a heart catheterisation, with an intervention in the heart vessel.
Danish: − Lægen kan også udskrive Lescol/Lescol XL for at forebygge flere alvorlige hjertetilfælde (fx hjerteanfald) hos patienter, der har gennemgået en ballonudvidelse ved et indgreb i hjertets blodårer.
English: The MAH has also implemented the statement from the EU worksharing Project.
Danish: Indehaveren af markedsføringstilladelsen har også medtaget erklæringen fra arbejdsdelingsprojektet på EU-plan.
English: Fluvastatin exerts its main effect in the liver, which is also the main organ for its metabolism.
Danish: Fluvastatin udøver hovedsagelig sin virkning i leveren, hvor det også hovedsagelig metaboliseres.
English: Although at present there is no clinical evidence that fluvastatin efficacy in lowering lipid levels is altered, for patients undertaking long-term rifampicin therapy (e.g. treatment of tuberculosis), appropriate adjustment of fluvastatin dosage may be warranted to ensure a satisfactory reduction in lipid levels.
Danish: Selvom der i øjeblikket ikke er klinisk bevis for, at fluvastatins effekt mht. sænkning af lipidniveauerne ændres, kan passende justering af fluvastatindosis have sin berettigelse hos patienter, der er i langvarig behandling med rifampicin (fx tuberkulosebehandling), for at sikre tilfredsstillende reduktion af lipidniveauet.
English: In the Lescol Intervention Prevention Study (LIPS), the effect of fluvastatin on major adverse cardiac events (MACE; i.e. cardiac death, non-fatal myocardial infarction and coronary revascularisation) was assessed in patients with coronary heart disease who had first successful percutaneous coronary intervention.
Danish: I LIPS-studiet (Lescol Intervention Prevention Study) blev fluvastatins effekt på alvorlige kardielle hændelser (MACE (major adverse cardiac events); dvs. hjertestop, ikke-fatalt myokardieinfarkt og koronar revaskularisering) vurderet hos patienter med koronar hjertesygdom og en første vellykket perkutan koronar intervention.
English: Marketing Authorisation Holder and Manufacturer For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder: [See Annex I - To be completed nationally]
Danish: Indehaver af markedsføringstilladelsen og fremstiller For information om denne medicin, kontakt din lokale repræsentant for indehaveren af markedsføringstilladelsen: [Se bilag I - Udfyldes nationalt]
English: Novartis Sverige AB Box 1150, 18311 Täby, Sweden
Danish: Novartis Sverige AB Box 1150
English: Biochemical abnormalities of liver function have been associated with HMG-CoA reductase inhibitors and other lipid-lowering agents.
Danish: Biokemiske leverfunktionsanomalier er blevet sat i forbindelse med HMG-CoA-reduktasehæmmere og andre lipidsænkende midler.
English: In the vast majority of EU Member States Lescol/Lescol XL is contraindicated in breastfeeding women and statement to this effect has been included by the MAH.
Danish: I langt størstedelen af medlemsstaterne er Lescol/Lescol XL kontraindiceret hos kvinder, der ammer, og indehaveren af markedsføringstilladelsen havde medtaget en erklæring herom.
English: The long-term efficacy of Lescol/Lescol XL therapy in childhood to reduce morbidity and mortality in adulthood has not been established.
Danish: Langtidsvirkningen af behandling med Lescol/Lescol XL i barndommen med hensyn til nedsat morbiditet og mortalitet i voksenalderen er ikke klarlagt (se pkt.
English: If muscular symptoms like pain, weakness or cramps occur in patients receiving fluvastatin, their CK levels should be measured.
Danish: Hvis patienter i behandling med fluvastatin oplever muskelsymptomer såsom smerter, svaghed eller kramper, skal deres CK-niveau måles.
English: • Exceptional cases of interstitial lung disease, especially with long term therapy (see section 4.4)
Danish: • Sjældne tilfælde af interstitial lungesygdom, særlig ved langtidsbrug (se pkt.
English: Concomitant administration of fluvastatin with bezafibrate, gemfibrozil, ciprofibrate or niacin (nicotinic acid) has no clinically relevant effect on the bioavailability of fluvastatin or the other lipid-lowering agent.
Danish: Samtidig administration af fluvastatin og bezafibrat, gemfibrozil, ciprofibrat eller niacin (nicotinsyre) har ingen klinisk relevant effekt på biotilgængeligheden af fluvastatin eller det andet lipidsænkende middel.
English: Fluvastatin treatment slowed the progression of coronary atherosclerosis lesions by 0.072 mm (95% confidence intervals for treatment difference from −0.1222 to −0.022 mm) over 2.5 years as measured by change in minimum lumen diameter (fluvastatin −0.028 mm vs. placebo −0.100 mm).
Danish: Fluvastatinbehandling forsinkede signifikant progressionen af koronare ateroskleroselæsioner med 0,072 mm (95 %-konfidensintervaller (KI) for behandlingsforskelle fra0,1222 til -0,022 mm) over 2,5 år, målt som ændringen i mindste lumendiameter (fluvastatin
English: This is also in line with all other statins posology recommendations.
Danish: Dette er også i overensstemmelse med den anbefalede dosering for andre statiner.
English: - if you have red or purple skin lesions (signs of blood vessel inflammation).
Danish: - hvis du får røde eller lilla sår på huden (tegn på betændelse i blodårene).
English: In a 24-week analysis, daily doses of 20 mg, 40 mg and 80 mg produced dose-related reductions in total-C, LDL-C, Apo B and in triglycerides and increases in HDL-C (see Table 2).
Danish: I en analyse ved uge 24 gav daglige doser på 20 mg, 40 mg og 80 mg dosisrelaterede fald i total-C, LDL-C, apoB og triglycerider og stigninger i HDL-C (se tabel 2).
English: The study included male and female patients (18 to 80 years old) and with baseline total-C levels ranging from 3.5 to 7.0 mmol/l (135 to 270 mg/dl).
Danish: Studiet omfattede mandlige og kvindelige patienter (18 til 80 år gamle) med baselineniveauer af total-C fra 3,5 til 7,0 mmol/l (135 til 270 mg/dl).
English: - Fibrates (e.g. gemfibrozil), nicotinic acid or bile acid sequestrants (medicines used to lower bad cholesterol levels).
Danish: - Fibrater (fx gemfibrozil), nicotinsyre eller galdesyrebindere (medicin, der bruges til at sænke mængden af ”dårligt” kolesterol).
English: Exceptional cases of interstitial lung disease have been reported with some statins, especially with long term therapy (see section 4.8).
Danish: Sjældne tilfælde af interstitial lungesygdom er blevet rapporteret ved brug af nogle statiner, særlig ved langtidsbrug (se pkt.
English: Your doctor will take a blood test before prescribing Lescol/Lescol XL.
Danish: Din læge vil tage en blodprøve, inden du får udskrevet Lescol/Lescol XL.
English: - if you have a thyroid disease (hypothyroidism).
Danish: - hvis du har en sygdom i skjoldbruskkirtlen (hypotyreose).
English: Based on pooled analyses of controlled clinical trials confirmed elevations of alanine aminotransferase or aspartate aminotranferase levels to more than 3 times the upper limit of normal occurred in 0.2% on Lescol capsules 20 mg/day, 1.5% to 1.8% on Lescol capsules 40 mg/day, 1.9% on Lescol XL tablets 80 mg/day and in 2.7% to 4.9% on twice daily Lescol capsules 40 mg.
Danish: På baggrund af poolede analyser af kontrollerede kliniske forsøg forekom der bekræftede stigninger i alanin-aminotransferase- eller aspartat-aminotranferasekoncentrationen på mere end 3 gange den øvre normalgrænse hos 0,2 %, som fik Lescol-kapsler 20 mg/dag, hos 1,5 % til 1,8 %, som fik Lescol-kapsler 40 mg/dag, hos 1,9 %, som fik Lescol XLdepottabletter 80 mg/dag, og hos 2,7 % til 4,9 %, som fik Lescol-kapsler 40 mg to gange daglig.
English: The first study enrolled 29 pre-pubertal boys, 9-12 years of age, who had an LDL-C level > 90th percentile for age and one parent with primary hypercholesterolaemia and either a family history of premature ischaemic heart disease or tendon xanthomas.
Danish: I det første studie blev der inkluderet 29 præpubertetsdrenge i alderen 9-12 år, som havde et LDL-Cniveau >90%-fraktilen for alder, og som havde en forælder med primær hyperkolesterolæmi og enten en familiær anamnese med iskæmisk hjertesygdom eller senexantomer.
English: Lescol, a fully synthetic cholesterol-lowering agent, is a competitive inhibitor of HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate, a precursor of sterols, including cholesterol.
Danish: Lescol, et udelukkende syntetisk kolesterolnedsættende middel, er en kompetitiv hæmmer af HMGCoA reduktase, som er ansvarlig for omdannelsen af HMG-CoA til mevalonat, en sterolprecurser, herunder kolesterol.
English: What Lescol/Lescol XL contains - The active substance is fluvastatin sodium
Danish: Lescol/Lescol XL indeholder: - Aktivt stof: fluvastatinnatrium
English: Austria, Belgium, Cyprus, Czech Republic, Denmark, Finland, France, Greece, Iceland, Ireland, Italy, Malta, Norway, Netherlands, Poland, Portugal, Romania, Slovak Republic, Spain, Sweden, United Kingdom
Danish: Belgien, Cypern, Danmark, Den Tjekkiske Republik, Finland, Frankrig, Grækenland, Holland, Irland, Island, Italien, Malta, Norge, Polen, Portugal, Rumænien, Slovakiet, Spanien, Storbritannien, Sverige, Østrig,
English: Despite the theoretical considerations concerning the role of cholesterol in embryo development, animal studies did not suggest an embryotoxic and teratogenic potential of fluvastatin.
Danish: Trods de teoretiske overvejelser vedrørende kolesterols rolle for fosters udvikling tydede dyreforsøg med fluvastatin ikke på embryotoksisk eller teratogent potentiale.
English: LIPS (study LES-EUR-01) was conducted to determine if fluvastatin therapy reduced the long-term risk of MACE (i.e. cardiac death, non-fatal myocardial infarction (MI) and coronary revascularisation) in CHD patients after a successful PCI.
Danish: LIPS (undersøgelse LES-EUR-01) blev gennemført for at fastslå, om fluvastatinbehandling nedsatte den langsigtede risiko for større kardielle hændelser (dvs. hjertedød, non-fatalt myokardieinfarkt og koronar revaskularisering) hos patienter med koronare hjertelidelser efter en vellykket perkutan koronar intervention.
English: [See Annex I - To be completed Nationally]
Danish: [Se bilag I - Udfyldes nationalt]
English: Hepatitis Skin and subcutaneous tissue disorders Rare:
Danish: Hud og subkutane væv Sjælden:
English: In the case of pre-pubertal children, as experience is very limited in this group, the potential risks and benefits should be carefully evaluated before the initiation of treatment.
Danish: Hos børn i præpuberteten skal de potentielle risici og fordele vurderes omhyggeligt, før behandlingen startes, da erfaring med behandling af denne gruppe er meget begrænset.
English: If any of these apply to you, do not take Lescol/ Lescol XL and tell your doctor.
Danish: Hvis noget af dette gælder for dig, må du ikke tage Lescol/Lescol XL, og du skal fortælle det til din læge.
English: Also, the relative reduction in LDL-C is similar across different baseline levels of LDL-C.
Danish: Den relative nedsættelse af LDL-kolesterol er ens for de forskellige baselineniveauer af LDL-kolesterol.
English: This leaflet was last approved in [To be completed nationally]
Danish: Denne indlægsseddel blev senest godkendt den [Udfyldes nationalt]
English: Caution should be exercised when Lescol/Lescol XL is administered to patients with a history of liver disease or heavy alcohol ingestion.
Danish: Forsigtighed tilrådes ved administration af Lescol/Lescol XL til patienter med leversygdom i anamnesen eller et stort alkoholforbrug.
English: Do not use Lescol/Lescol XL after the expiry date which is stated on the carton and blister after [To be completed nationally].
Danish: Brug ikke Lescol/Lescol XL efter den udløbsdato, der står på pakning og blisterkort.
English: Gesundheitsproducte GmbH Ruhlandstrasse 5, 83646 Bad Töltz,
Danish: Ruhlandstrasse 5, 83646 Bad Töltz Tyskland
English: Children and adolescents with heterozygous familial hypercholesterolaemia In patients aged < 18 years, efficacy and safety have not been studied for treatment periods longer than two years.
Danish: Børn og unge med heterozygot familiær hyperkolesterolæmi Virkning og sikkerhed er ikke undersøgt hos patienter <18 år for behandlingsperioder på mere end to år.
English: 114 patients (66 boys and 48 girls) were treated with fluvastatin administered as either Lescol capsules (20 mg/day to 40 mg twice daily) or Lescol XL 80 mg prolonged-release tablets once daily using a dose-titration regimen based upon LDL-C response.
Danish: 114 patienter (66 drenge og 48 piger) blev behandlet med fluvastatin, der blev administreret enten som Lescol-kapsler (20 mg/dag til 40 mg to gange daglig) eller som Lescol XL 80 mg depottablet én gang daglig ved brug af et dosistitreringsregime baseret på LDL-C-respons.
English: In 12 placebo-controlled studies in patients with Type IIa or IIb hyperlipoproteinaemia, Lescol alone was administered to 1,621 patients in daily dose regimens of 20 mg, 40 mg and 80 mg (40 mg twice daily) for at least 6 weeks duration.
Danish: I 12 placebokontrollerede studier med patienter med type IIa eller IIb hyperlipoproteinæmi blev Lescol monoterapi administreret til 1.621 patienter i daglige dosisregimer på 20 mg, 40 mg og 80 mg (40 mg to gange daglig) i mindst 6 uger.
English: If you take more Lescol/Lescol XL than you should If you have accidentally taken too much Lescol/Lescol XL, talk to your doctor straight away.
Danish: Hvis du har taget for mange Lescol/Lescol XL Hvis du ved et uheld har taget for meget Lescol/Lescol XL, skal du straks kontakte lægen.
English: A variety of changes were identified in toxicity studies that are common to HMG-CoA reductase inhibitors.
Danish: I toksicitetsundersøgelserne blev der påvist en række ændringer, som er almindelige for HMG-CoAreduktasehæmmere.
English: The CHMP agreed with the following wording proposed by the MAH: ‘In patients with coronary heart disease after percutaneous coronary interventions the appropriate daily dose is 80 mg.'
Danish: CHMP vedtog følgende formulering foreslået af indehaveren af markedsføringstilladelsen: "Hos patienter med koronar hjertesygdom efter perkutan koronar intervention er en daglig dosis på 80 mg passende."
English: Since an increased risk of myopathy and/or rhabdomyolysis has been observed in patients receiving HMGCoA reductase inhibitors together with any of these molecules, the benefit and the risk of concurrent treatment should be carefully weighed and these combinations should only be used with caution (see section
Danish: Da der er observeret en øget risiko for myopati og/eller rabdomyolyse hos patienter i behandling med HMG-CoA-reduktasehæmmere sammen med disse stoffer, skal fordele og risici ved samtidig behandling omhyggeligt afvejes, og disse kombinationer må kun anvendes med forsigtighed (se pkt.
English: Starting and maintenance doses should be individualized according to the baseline LDL-C levels and the treatment goal to be accomplished.
Danish: Start- og vedligeholdelsesdosis skal tilpasses individuelt ud fra baselineniveau af LDL-kolesterol (LDL-C) og det behandlingsmål, der skal nås.
English: 08029 Barcelona Spain
Danish: 08029 Barcelona Spanien
English: 20 mg and 40 mg capsules Member State
Danish: 20 mg og 40 mg kapsler Medlemsland
English: If you are pregnant, consult your doctor or pharmacist before taking Lescol/Lescol XL.
Danish: Hvis du er gravid, skal du kontakte lægen eller apoteket, inden du tager Lescol/Lescol XL.
English: The CHMP agreed with the following wording proposed by the MAH for this indication: ‘Secondary prevention of major adverse cardiac events in adults with coronary heart disease after percutaneous coronary interventions (see section 5.1).'
Danish: CHMP godkendte følgende ordlyd foreslået af indehaveren af markedsføringstilladelsen for denne indikation: "Sekundær forebyggelse af større utilsigtede kardielle hændelser hos voksne med koronar hjertesygdom efter perkutan koronar intervention (se afsnit 5.1)."
English: Isolated cases of myopathy have been reported post-marketing for concomitant administration of fluvastatin with ciclosporin and fluvastatin with colchicines.
Danish: Enkeltstående tilfælde af myopati er blevet rapporteret efter markedsføring ved samtidig administration af fluvastatin og ciclosporin og fluvastatin og colchicin.
English: SPECIAL STORAGE CONDITIONS [To be completed Nationally]
Danish: SÆRLIGE OPBEVARINGSBETINGELSER [Udfyldes nationalt]
English: If muscular symptoms are severe and cause daily discomfort, even if CK levels are elevated to ≤ 5x ULN, treatment discontinuation should be considered.
Danish: Hvis muskelsymptomerne er svære og medfører daglige gener, skal det overvejes at seponere behandlingen, selvom CK-forhøjelsen er ≤5 x øvre normalgrænse.
English: No dose adjustments are therefore necessary in these patients however, due to limited experience with doses >40mg/day in case of severe renal impairment (CrCL <0,5 mL/sec or 30 mL/min), these doses should be initiated with caution.
Danish: Der kræves derfor ingen dosisjustering hos disse patienter, men på grund af begrænset erfaring med doser >40 mg/dag til patienter med svært nedsat nyrefunktion (kreatininclearance <0,5 ml/s eller 30 ml/min) skal disse doser dog påbegyndes med forsigtighed.
English: - Fluconazole (a medicine used to treat fungal infections).
Danish: - Fluconazol (medicin, der bruges mod svampeinfektioner).
English: If any of these apply to you, tell your doctor before you take Lescol/Lescol XL.
Danish: Hvis noget af dette gælder for dig, skal du fortælle det til din læge, før du tager Lescol/Lescol XL.
English: Fluvastatin, a fully synthetic cholesterol-lowering agent, is a competitive inhibitor of HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate, a precursor of sterols, including cholesterol.
Danish: Fluvastatin, et fuldt ud syntetisk kolesterolsænkende middel, er en kompetitiv hæmmer af HMG-CoAreduktase, som er ansvarlig for omdannelsen af HMG-CoA til mevalonat, et forstadie for steroler, inklusive kolesterol.
English: If you become pregnant while taking this medicine, stop taking Lescol/Lescol XL and see your doctor.
Danish: Hvis du bliver gravid, mens du tager medicinen, skal du stoppe med at tage Lescol/Lescol XL og tale med lægen.
English: Given as a single daily dose of 80 mg, Lescol XL significantly reduced total-C, LDL-C, triglycerides (TG) and Apo B (see Table 2).
Danish: Givet som en enkelt daglig dosis på 80 mg reducerede Lescol XL total-C, LDL-C, triglycerider (TG) og apoB signifikant (se tabel 2).