FrancophonIA/ELRC3.0 huggingface dataset:
English: Significant lowering of intraocular pressure can be maintained for periods exceeding 24 hours with a single dose.
Croatian: Značajno sniženje intraokularnog tlaka može se održati kroz period koji premašuje 24 sata s pojedinačnom dozom.
English: Do not drive or use machines until this has worn off.
Croatian: Nemojte upravljati vozilima i strojevima sve dok se vid ne razbistri.
English: Travoprost must not be used in women of childbearing age/potential unless adequate contraceptive measures are in place (see section 5.3).
Croatian: Travoprost ne smiju koristiti žene u reproduktivnoj dobi/koje mogu zatrudnjeti, osim ako nisu poduzete adekvatne mjere kontracepcije (vidjeti dio 5.3).
English: Cartons containing 1 or 3 bottles.
Croatian: Kutije sadrže 1 ili 3 bočice.
English: If you forget to use IZBA
Croatian: Ako ste zaboravili primijeniti IZBU
English: If you or your child are using other eye preparations such as eye drop or eye ointment, wait for at least 5 minutes between putting in IZBA and the other eye preparations.
Croatian: Ako Vi ili Vaše dijete koristite i druge lijekove za oko poput kapi ili masti za oči, pričekajte najmanje 5 minuta između primjene IZBE i drugih lijekova za oko.
English: The change in iris colour occurs slowly and may not be noticeable for months to years.
Croatian: Promjena boje šarenice nastaje polako i može se razvijati neprimjetno kroz više mjeseci ili godina.
English: • Close the bottle cap firmly immediately after use.
Croatian: • Bočicu čvrsto zatvorite odmah nakon primjene.
English: In a similar 3-month study in adult patients, these events occurred at an incidence of 11.4% and 0%, respectively.
Croatian: U sličnom 3-mjesečnom ispitivanju u odraslih bolesnika, incidencija pojavljivanja tih događaja bila je 11,4% odnosno 0%.
English: Typically, the brown pigmentation around the pupil spreads concentrically towards the periphery in affected eyes, but the entire iris or parts of it may become more brownish.
Croatian: Tipično je da se smeđa pigmentacija oko zjenice širi koncentrično prema periferiji oboljelog oka, ali cijela šarenica ili njezini dijelovi mogu postati više smeđi.
English: 1 bottle of 2.5 mL 3 bottles of 2.5 mL
Croatian: 1 bočica od 2,5 ml 3 bočice od 2,5 ml
English: Increased palpebral fissure observed in monkeys were not seen in rabbits or in the clinical trials with travoprost products and is considered to be species specific.
Croatian: Povećanje palpebralne fisure zabilježeno kod majmuna nije viđeno kod kunića niti u kliničkim ispitivanjima s travoprost lijekovima i smatra se specifičnim za vrstu.
English: Month 3
Croatian: Mjesec 3
English: The most frequent adverse reactions reported in the paediatric population were ocular hyperaemia (16.9%) and growth of eyelashes (6.5%).
Croatian: Najučestalije nuspojave prijavljene u pedijatrijskoj populaciji bile su okularna hiperemija (16,9%) i rast trepavica (6,5%).
English: • After using IZBA, keep the eyelid closed, apply gentle pressure by pressing a finger into the corner of the eye, by the nose (picture 4) for at least 1 minute.
Croatian: • Nakon ukapavanja IZBE, držite vjeđu zatvorenom, pritisnite prstom kut oka blizu nosa na najmanje 1 minutu (slika 4).
English: What IZBA looks like and contents of the pack
Croatian: Kako IZBA izgleda i sadržaj pakiranja
English: Discard 4 weeks after first opening.
Croatian: Baciti 4 tjedna nakon prvog otvaranja.
English: The safety and efficacy of IZBA in children below the age of 3 years have not been established.
Croatian: Sigurnost i djelotvornost IZBE u djece ispod 3 godine nisu ustanovljene.
English: Write down the date you opened it in the space on each carton box.
Croatian: Zapišite datum otvaranja na za to predviđeno mjesto na svakoj kutiji.
English: The mean percent reductions in IOP from baseline to each study visit and assessment time point ranged from 28.4% to 30.7%.
Croatian: Srednja vrijednost postotka sniženja IOT od početnog je u svakom posjetu tijekom studije i vremenu procjene bila u rasponu od 28,4% do 30,7%.
English: The effect on IOP was seen after the second week of treatment and was consistently maintained throughout the 12 week period of study for all age groups.
Croatian: Učinak na IOT zabilježen je nakon drugog tjedna liječenja te se konzistentno održavao kroz 12 tjedana ispitivanja, u svim dobnim skupinama.
English: Metabolism is the major route of elimination of both travoprost and the active free acid.
Croatian: Metaboliziranje je glavni put eliminacije i travoprosta i aktivne slobodne kiseline.
English: No dosage adjustment is necessary in these patients.
Croatian: Nije potrebno prilagođavanje doze kod ovih bolesnika.
English: A topical overdose is not likely to occur or to be associated with toxicity.
Croatian: Topikalno predoziranje nije očekivano niti povezano s toksičnošću.
English: If you think that you may be pregnant speak with your doctor right away.
Croatian: Ako sumnjate na trudnoću, odmah razgovarajte sa svojim liječnikom.
English: IZBA may increase the risk of inflammation of the back of the eye.
Croatian: IZBA može povećati rizik upale stražnjeg dijela oka.
English: IZBA may gradually change eyelashes in the treated eye(s); these changes were observed in about half of the patients in clinical trials and include: increased length, thickness, pigmentation, and/or number of lashes.
Croatian: IZBA može postupno mijenjati trepavice liječenog oka (očiju); ove su promjene opažene kod oko polovice bolesnika u kliničkim ispitivanjima i uključuju: povećanje duljine, debljine, pigmentacije i/ili broja trepavica.
English: When substituting another ophthalmic antiglaucoma medicinal product with IZBA, the other medicinal product should be discontinued and IZBA should be started the following day.
Croatian: Kada se drugi topikalni oftalmički antiglaukomski lijek zamjenjuje IZBOM, mora se prekinuti primjena drugog lijeka i započeti s primjenom IZBE sljedećeg dana.
English: What IZBA is and what it is used for What you need to know before you use IZBA How to use IZBA
Croatian: Što je IZBA i za što se koristi Što morate znati prije nego počnete primjenjivati IZBU Kako primjenjivati IZBU
English: Tiny amounts of hydrochloric acid or sodium hydroxide are added to keep acidity levels (pH levels) normal.
Croatian: Male količine kloridne kiseline ili natrijevog hidroksida dodane su za održavanje normalne razine kiselosti (pH vrijednosti).
English: A topical overdose of travoprost may be flushed from the eye(s) with lukewarm water.
Croatian: Topikalno predozirani travoprost može se isprati iz oka (očiju) toplom vodom.
English: Always use this medicine exactly as your doctor or the doctor treating your child has told you.
Croatian: Uvijek primijenite ovaj lijek točno onako kako Vam je rekao liječnik ili liječnik Vašeg djeteta.
English: Not known dysuria, urinary incontinence
Croatian: Nepoznato dizurija, urinarna inkontinencija
English: This may reduce the systemic absorption of medicinal products administered via the ocular route and result in a decrease in systemic adverse reactions.
Croatian: To može smanjiti sustavnu apsorpciju lijeka primijenjenog u oko i rezultirati smanjenjem sustavnih nuspojava.
English: The dose should not exceed one drop in the affected eye(s) daily.
Croatian: Doza ne smije prekoračiti jednu kap u oboljelo oko (oči) na dan.
English: Skin contact with IZBA must be avoided as transdermal absorption of travoprost has been demonstrated in rabbits.
Croatian: Kontakt kože s IZBOM mora se izbjegavati jer je transdermalna apsorpcija travoprosta pokazana u kunića.
English: IZBA can be used in children from 3 years to <18 years at the same dose as for adults.
Croatian: IZBA se može primjenjivati u djece u dobi od 3 godine do <18 godina u istoj dozi kao i za odrasle.
English: Both side effects were observed with a higher incidence in children and adolescents compared to adults.
Croatian: Obje nuspojave češće su zabilježene u djece i adolescenata nego u odraslih.
English: Talk to your doctor or pharmacist before using IZBA.
Croatian: Obratite se svom liječniku ili ljekarniku prije nego primijenite IZBU.
English: Mean Difference a
Croatian: Srednja vrijednost razlike a
English: Macular oedema has been reported during treatment with prostaglandin F2a analogues.
Croatian: Edem makule je bio prijavljen tijekom liječenja analozima prostangladina F2a.
English: • Immediately before using a bottle for the first time, tear open the overwrap pouch, take the bottle out (picture 1) and write the date of opening on the carton in the space provided.
Croatian: • Zaštitni vanjski omot (vrećicu) otvorite neposredno prije prve primjene (slika 1), izvadite bočicu i zapišite datum otvaranja na kutiji na označenom mjestu.
English: Animal studies showed no effect of travoprost on fertility at doses more than 250 times the maximum recommended human ocular dose.
Croatian: Studije na životinjama pokazale su da nema učinka na plodnost kod primjene travoprosta u dozama većim od 250 puta od maksimalno preporučene doze za primjenu u oko kod ljudi.
English: You may find that your vision is blurred for a time just after you use IZBA.
Croatian: Može se dogoditi da Vam se vid zamuti neko vrijeme neposredno nakon primjene IZBE.
English: Temporary blurred vision or other visual disturbances may affect the ability to drive or use machines.
Croatian: Prolazno zamućenje vida ili drugi vidni poremećaji mogu utjecati na sposobnost upravljanja vozilima ili rada na strojevima.
English: Travoprost free acid and its metabolites are mainly excreted by the kidneys.
Croatian: Travoprost slobodna kiselina i njezini metaboliti većim dijelom se izlučuju putem bubrega.
English: It is absorbed through the cornea where the isopropyl ester is hydrolysed to the active free acid.
Croatian: Apsorbira se kroz rožnicu gdje se izopropilni ester hidrolizira u aktivnu slobodnu kiselinu.
English: Periorbital and lid changes including deepening of the eyelid sulcus have been observed with prostaglandin analogues.
Croatian: Periorbitalne i promjene na vjeđama, uključujući produbljivanje sulkusa vjeđa, zabilježene su kod uporabe analoga prostanglandina.
English: Aqueous humour concentrations declined with a half-life of approximately 1.5 hours.
Croatian: Koncentracija u očnoj vodici se smanjuje s poluvremenom od otprilike 1,5 sat.
English: Thereafter, plasma levels declined rapidly to below the 10 pg/mL assay quantitation limit before 1 hour post-administration.
Croatian: Nakon toga, razina u plazmi brzo pada ispod limita kvantitativnog testa od 10 pg/ml prije isteka jednog sata nakon primjene.
English: Topical ocular administration of travoprost to monkeys at concentrations of up to 0.012% to the right eye, twice daily for one year resulted in no systemic toxicity.
Croatian: Topikalna primjena travoprosta u oko kod majmuna pri koncentracijama do 0,012% u desno oko dvaput dnevno tijekom jedne godine, nije rezultirala sistemskom toksičnošću.
English: One drop in the affected eye or eyes, once a day in the evening.
Croatian: Jedna kap u oko (ili oči) koje se liječi, jednom dnevno - navečer.
English: The mechanism of eyelash changes and their long-term consequences are currently unknown.
Croatian: Mehanizam promjena na trepavicama i dugoročne posljedice u svezi s tim trenutno nisu poznate.
English: Novartis Bulgaria EOOD Тел.
Croatian: Novartis Bulgaria EOOD.
English: In the unlikely event of coming in contact with a substantial portion of the contents of the bottle, thoroughly cleanse the exposed area immediately.
Croatian: U slučajnom dodiru sa većom količinom sadržaja bočice, potrebno je odmah i temeljito oprati mjesto izlaganja.
English: One mL of solution contains 7.5 mg propylene glycol and 2 mg polyoxyethylene hydrogenated castor oil 40 (HCO-40) (see section 4.4).
Croatian: Jedan ml otopine sadrži 7,5 mg propilenglikola i 2 mg polioksietilen hidrogeniranog ricinusovog ulja 40 (HCO-40) (vidjeti dio 4.4).
English: Secondary pharmacology
Croatian: Sekundarna farmakologija
English: • If you have current or previous history of an eye inflammation (iritis and uveitis) talk to your doctor before you use IZBA.
Croatian: • Ako imate ili ste imali upalu oka (iritis i uveitis) razgovarajte sa svojim liječnikom prije primjene IZBE.
English: Low levels of radioactivity were measured in amniotic fluid and foetal tissues of pregnant rats administered
Croatian: Niske razine radioaktivnosti izmjerene su u amnionskoj tekućini i tkivima fetusa skotnih ženki štakora kojima je davan
English: Not known depression, anxiety, insomnia
Croatian: Nepoznato depresija, anksioznost, nesanica
English: Rare musculoskeletal pain, arthralgia
Croatian: Rijetko mišićnokoštana bol, artralgija
English: • IZBA may gradually change the colour of your iris (the coloured part of your eye).
Croatian: • IZBA može postepeno promijeniti boju šarenice (obojeni dio oka).
English: In addition, the following side effects have been observed with another medicine containing a higher strength of travoprost (40 micrograms/mL):
Croatian: Dodatno sljedeće su nuspojave opažene s drugim lijekovima koji sadrže veću jačinu travoprosta (40 mikrograma/ml):
English: The following side effects have been observed with IZBA:
Croatian: Sljedeće su nuspojave opažene s IZBOM:
English: It is unknown whether travoprost from eye drops is excreted in human breast milk.
Croatian: Nije poznato izlučuje li se travoprost iz kapi za oko u majčino mlijeko u ljudi.
English: The change in eye colour has predominantly been seen in patients with mixed coloured irides, i.e., blue-brown, grey-brown, yellow-brown and green-brown; however, it has also been observed in patients with brown eyes.
Croatian: Promjena boje oka uglavnom se opaža kod bolesnika s mješovito obojenim šarenicama, npr. plavosmeđe, sivosmeđe, žutosmeđe i zelenosmeđe, međutim opažena je također kod bolesnika sa smeđim očima.
English: IZBA has no or negligible influence on the ability to drive and use machines.
Croatian: IZBA ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Pruritus, hair growth abnormal
Croatian: Nepoznato svrbež, abnormalan rast dlaka
English: If you or your child use more IZBA than you should Rinse all the medicine out with warm water.
Croatian: Ako sebi ili svom djetetu primijenite više IZBE nego što ste trebali Isperite oko mlakom vodom.
English: Eye inflammation is a possible side effect which may be associated with the use of prostaglandin analogues such as IZBA.
Croatian: Upala oka moguća je nuspojava koja može biti povezana s korištenjem analoga prostaglandina poput IZBE.
English: Pull down the eyelid with a clean finger, until there is a ‘pocket' between the eyelid and the eye.
Croatian: Donju vjeđu čistim prstom lagano povucite prema dolje, tako da nastane „prostor“ između vjeđe i oka.
English: General side effects: rash or itching of the skin.
Croatian: Opće nuspojave: osip ili svrbež kože.
English: IOP reductions for this group were based on only 6 patients in the timolol group and 9 patients in the travoprost group where 4 patients in the travoprost group versus 0 patients in the timolol group had no relevant mean IOP reduction at Week 12.
Croatian: Sniženja IOT-a za ovu skupinu temeljena su na samo 6 bolesnika u skupini koja je primala timolol i 9 bolesnika u skupini koja je primala travoprost, gdje 4 bolesnika u skupini koja je primala travoprost odnosno 0 bolesnika u skupini koja je primala timolol nije imalo relevantne srednje vrijednosti sniženja IOT-a u 12. tjednu.
English: Mean IOP reductions in the travoprost and timolol groups were similar (see Table 4).
Croatian: Srednje vrijednosti sniženja IOT-a u skupinama koje su primale travoprost odnosno timolol bile su slične (vidjeti Tablicu 4).
English: Visit
Croatian: Posjeta
English: Additional adverse reactions reported in paediatric patients in the 3-month paediatric study (n=77) compared to a similar trial in adults (n=185) included erythema of eyelid, keratitis, lacrimation increased, and photophobia, all reported as single events with an incidence of 1.3% versus 0.0% seen in adults.
Croatian: Dodatne nuspojave prijavljene u pedijatrijskih bolesnika u 3-mjesečnom pedijatrijskom ispitivanju (n=77) u usporedbi sa sličnim ispitivanjem u odraslih (n=185) uključivale su eritem vjeđe, keratitis, pojačano suzenje i fotofobiju, a sve su bile prijavljene kao pojedinačni događaji s incidencijom od 1,3% u usporedbi s 0,0% primijećenih u odraslih.
English: In ocular toxicity studies in monkeys, administration of travoprost at a dose of 0.45 microgram, twice a day, was shown to induce increased palpebral fissure.
Croatian: U studijama očne toksičnosti u majmuna primjena travoprosta u dozi od 0,45 mikrograma, dvaput dnevno, pokazala je induciranje povećanja palpebralne fisure.
English: CARTON FOR SINGLE BOTTLE 4.0 mL + CARTON FOR 3 x 4.0 mL BOTTLES
Croatian: KUTIJA ZA JEDNU BOČICU OD 4,0 ml + KUTIJA ZA 3 BOČICE x 4,0 ml
English: Rare heart rate irregular, heart rate decreased
Croatian: Rijetko nepravilni srčani ritam, usporeni otkucaji srca
English: Week 6
Croatian: Tjedan 6
English: Each 4 mL bottle will contain 2.5 mL of solution.
Croatian: Svaka bočica od 4 ml sadrži 2,5 ml otopine.
English: Reproduction and development studies have demonstrated a potent effect on foetal loss with a high rate observed in rats and mice (180 pg/mL and 30 pg/mL plasma, respectively) at exposures 1.2 to 6 times the clinical exposure (up to 25 pg/mL).
Croatian: Studije reprodukcije i razvoja su pokazale snažni učinak na gubitak fetusa s visokom stopom primijećenom u štakora i miševa (180 pg/ml odnosno 30 pg/ml plazme) kod ekspozicije dozama 1,2 do 6 puta većim od kliničke ekspozicije (do 25 pg/ml).
English: • Do not touch the eye or eyelid, surrounding areas or other surfaces with the dropper.
Croatian: • Izbjegavajte dodir kapaljke s okom ili vjeđom, okolnim područjima oka ili drugim površinama.
English: In children and adolescents, the most common side effects seen with the medicine containing a higher strength of travoprost (40 micrograms/mL) are eye redness and growth of eyelashes.
Croatian: U djece i adolescenata najčešće nuspojave uočene uz lijek koji sadrži veću jačinu travoprosta (40 mikrograma/ml) bile su crvenilo oka i rast trepavica.
English: IZBA contains travoprost, one of a group of medicines called prostaglandin analogues.
Croatian: IZBA sadrži travoprost, jedan od lijekova iz skupine pod nazivom analozi prostaglandina.
English: In pregnant rat, systemic administration of travoprost at doses more than 200 times the clinical dose during the period of organogenesis resulted in an increased incidence of malformations.
Croatian: Kod skotne ženke štakora sistemska primjena travoprosta u dozama većim od 200 puta od kliničke doze, tijekom razdoblja organogeneze, rezultirala je povećanom incidencijom malformacija.
English: 10 SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF APPROPRIATE
Croatian: POSEBNE MJERE ZA ZBRINJAVANJE NEISKORIŠTENOG LIJEKA ILI OTPADNIH MATERIJALA KOJI POTJEČU
English: It could infect the drops.
Croatian: Može doći do kontaminacije kapi.
English: In the age groups 3 to <12 years (n=36) and 12 to <18 years (n=26), mean IOP reduction at Week 12 in the travoprost group was similar to that in the timolol group.
Croatian: U dobnim skupinama od 3 do <12 godina (n=36) i od 12 do <18 godina (n=26), srednja vrijednost sniženja IOT-a u 12. tjednu u skupini koja je primala travoprost bila je slična onoj u skupini koja je primala timolol.
English: IZBA should only be used as an eye drop.
Croatian: IZBU primjenjujte samo kao kapi za oko.
English: Travoprost, a prostaglandin F2 analogue, is a highly selective full agonist which has a high affinity for the prostaglandin FP receptor, and reduces the intraocular pressure by increasing the outflow of aqueous humour via trabecular meshwork and uveoscleral pathways.
Croatian: Travoprost, analog prostaglandina F2, potpuni je agonist koji je visoko selektivan i ima visoki afinitet za prostaglandin FP receptor, i snižava intraokularni tlak povećanjem oticanja očne vodice kroz trabekularnu mrežicu i uveoskleralnim putem.
English: The systemic metabolic pathways parallel those of endogenous prostaglandin F2 which are characterised by reduction of the double bond in position C13-C14, oxidation of the 15-hydroxyl and -oxidative cleavages of the upper side chain.
Croatian: Sistemski metabolički putevi paralelni su s onima endogenih prostaglandina F2α, za koje je karakteristična redukcija C13-C14 dvostruke veze, oksidacija 15-hidroksilnih i β-oksidacijsko cijepanje gornjeg postraničnog lanca.
English: To prevent contamination of the dropper tip and solution, care must be taken not to touch the eyelids, surrounding areas or other surfaces with the dropper tip of the bottle.
Croatian: Da bi se spriječila kontaminacija vrha kapaljke i otopine, mora se izbjegavati dodir vrha kapaljke s vjeđama, okolnim područjima ili drugim površinama.
English: Rare blood pressure diastolic decreased, blood pressure systolic increased, hypotension, hypertension
Croatian: Rijetko sniženje dijastoličkog krvnog tlaka, povišenje sistoličkog krvnog tlaka, hipotenzija, hipertenzija
English: The following adverse reactions were assessed to be related with travoprost 40 µg/mL eye drops, solution (either benzalkonium chloride [BAK] or Polyquad-preserved) and are classified according to the following convention: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000) and not known (cannot be estimated from the available data).
Croatian: Sljedeće su nuspojave povezane s travoprost 40 µg/ml kapima za oko, otopinom (bilo s benzalkonijevim kloridom [BAK] ili polikvadom kao konzervansom) i razvrstane su prema sljedećem dogovoru: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000) ili nepoznato (ne može se procijeniti iz dostupnih podataka).
English: In a clinical trial of 3 months duration (N=442) involving IZBA as monotherapy, the most common adverse reaction observed was hyperaemia of the eye (ocular or conjunctival) reported in approximately 12% of the patients.
Croatian: U kliničkoj studiji u trajanju od 3 mjeseca (N=442) koja je uključila IZBU kao monoterapiju, najčešće zabilježena nuspojava bila je hiperemija oka (okularna ili konjunktivalna) prijavljena u otprilike 12% bolesnika.
English: Decrease of elevated intraocular pressure in adult patients with ocular hypertension or open-angle glaucoma (see section 5.1).
Croatian: Sniženje povišenog intraokularnog tlaka u odraslih bolesnika s očnom hipertenzijom ili glaukomom otvorenog kuta (vidjeti dio 5.1).
English: Rare: may affect up to 1 in 1,000 people
Croatian: Rijetko: mogu se pojaviti u manje od 1 na 1000 osoba
English: Not known chest pain, bradycardia, tachycardia, arrhythmia
Croatian: Nepoznato bol u prsima, bradikardija, tahikardija, aritmija
English: Findings are related to FP receptor agonist activity in uterus with early embryolethality, post-implantation loss, foetotoxicity.
Croatian: Nalazi su povezani s aktivnosti agonista FP receptora u uterusu i uključuju ranu smrtnost embrija, postimplantacijski gubitak i fetotoksičnost.
English: The studies used in the model were two dose response trials, one Phase III study using IZBA and a paediatric study using TRAVATAN (travoprost 40 micrograms/mL eye drops, solution).
Croatian: Ispitivanja korištena u modelu bila su ispitivanja odgovora na dvije doze, jedno ispitivanje faze III u kojem se primjenjivala IZBA i pedijatrijsko ispitivanje u kojem se primjenjivao TRAVATAN (travoprost 40 mikrograma/ml kapi za oko, otopina).
English: Use of IZBA is not recommended to those children under 3 years of age.
Croatian: Primjena IZBE se ne preporučuje u djece mlađe od 3 godine.
English: Not known vertigo, tinnitus
Croatian: Nepoznato vrtoglavica, tinitus
English: Mean IOP reduction at Week 12 in the 2 months to <3 years of age group was 1.8 mmHg in the travoprost group and 7.3 mmHg in the timolol group.
Croatian: Srednja vrijednost sniženja IOT-a u 12. tjednu u dobnoj skupini od 2 mjeseca do <3 godine bila je 1,8 mmHg u skupini koja je primala travoprost i 7,3 mmHg u skupini koja je primila timolol.