FrancophonIA/ELRC3.0 huggingface dataset:
English: A randomised open-label study compared the HIV RNA suppression of nelfinavir 1250 mg BID versus nelfinavir 750 mg TID in PI naïve patients also receiving stavudine (30-40 mg BID) and lamivudine (150 mg BID).
Danish: En åben, randomiseret undersøgelse sammenlignede suppression af hiv-RNA efter hhv. nelfinavir 1250 mg BID og nelfinavir 750 mg TID hos PI-naive patienter, som også fik stavudin (30-40 mg BID) og lamivudin (150 mg BID).
English: Interactions of nelfinavir with selected compounds that describe the impact of nelfinavir on the pharmacokinetics of the co-administered compound and the impact of other drugs on pharmacokinetics of nelfinavir are listed in Table 1.
Danish: Nelfinavirs interaktioner med udvalgte forbindelser er anført i tabel 1, som beskriver nelfinavirs indvirkning på farmakokinetikken af de samtidigt administrerede stoffer og indvirkningen af andre
English: Herbal preparations containing St. John's wort (Hypericum perforatum) must not be used while taking nelfinavir due to the risk of decreased plasma concentrations and reduced clinical effects of nelfinavir (see section 4.5).
Danish: Urtepræparater, der indeholder perikon (Hypericum perforatum), må ikke anvendes under behandling med nelfinavir på grund af risiko for nedsat plasmakoncentration og nedsat klinisk effekt af nelfinavir
English: Metabolic enzyme inhibitors: Co-administration of nelfinavir with inhibitors of CYP2C19 (e.g., fluconazole, fluoxetine, paroxetine, lansoprazole, imipramine, amitriptyline and diazepam) may be expected to reduce the conversion of nelfinavir to its major active metabolite M8 (tert-butyl hydroxy nelfinavir) with a concomitant increase in plasma nelfinavir levels (see section 5.2).
Danish: Metaboliske enzymhæmmere: Samtidig administration af nelfinavir og CYP2C19 hæmmere (f.eks. fluconazol, fluoxetin, paroxetin, lansoprazol, imipramin, amitriptylin og diazepam) kan forventes at reducere omsætningen af nelfinavir til dets aktive hovedmetabolit M8 (tert-butyl hydroxynelfinavir), med ledsagende stigning i plasmakoncentrationen af nelfinavir (se pkt.
English: Oral Contraceptives 17 α-Ethinyl estradiol 35 μg qd x 15 days (Nelfinavir 750 mg q8h x 7 days)
Danish: Orale kontraceptiva 17 α-ethinylestradiol 35 μg 1 gang daglig i 15 dage (Nelfinavir 750 mg hver 8. time i 7 dage)
English: Rare (≥ 0.01 % - ≤ 0.1 %): hepatitis, hepatic enzymes increased and jaundice when nelfinavir is used in combination with other antiretroviral agents.
Danish: Sjælden (≥ 0,01 % - ≤ 0,1 %): Hepatitis, stigning i leverenzymer og ikterus, når nelfinavir er anvendt i kombination med andre antiretrovirale stoffer.
English: The oral powder may be mixed with a small amount of water, milk, formula, soy formula, soy milk, dietary supplements, or pudding.
Danish: Det orale pulver kan blandes med lidt vand, mælk, modermælkserstatning, soja-modermælkserstatning, sojamælk, kosttilskud eller budding.
English: Use with increased monitoring for adverse events associated with increased exposure to sildenafil.
Danish: Anvend under nøje overvågning for bivirkninger forbundet med øget eksponering for sildenafil.
English: At week 48, 63 % nelfinavir and 75 % lopinavir/ritonavir patients had HIV-1 RNA < 400 copies/ml, whereas 52 % nelfinavir and 67 % lopinavir/ritonavir patients had HIV-1 RNA <50 copies/ml (intent-to-treat, missing = failure).
Danish: Efter 48 uger havde 63 % af nelfinavirpatienterne og 75 % af lopinavir/ritonavirpatienterne < 400 kopier/ml hiv-1-RNA, hvorimod 52 % af nelfinavirpatienterne og 67 % af lopinavir/ritonavirpatienterne havde < 50 kopier/ml hiv-1RNA (intent-to-treat, manglende = svigt).
English: In patients, the nelfinavir AUC0-24 with 1250 mg BID administration was 52.8 ± 15.7 µg⋅h/ml (n=10) and with 750 mg TID administration was 43.6 ± 17.8 µg⋅h/ml (n=11).
Danish: Hos patienter var nelfinavir AUC0-24 52,8 ± 15,7 μg⋅time/ml (n=10) ved administration af 1250 mg to gange daglig og 43,6 ± 17,8 μg⋅time/ml (n=11) ved administration af 750 mg tre gange daglig.
English: - Contains potassium: 50.0 mg of dibasic potassium phosphate corresponding to 22.5 mg of See section 4.4
Danish: - Indeholder kalium: 50,0 mg dikaliumphosphat svarende til 22,5 mg kalium pr. gram oralt
English: Mothers must be instructed to discontinue breast-feeding if they are receiving VIRACEPT.
Danish: Hvis mødre tager VIRACEPT, bør de instrueres i at afbryde amningen.
English: VIRACEPT 50 mg/g oral powder Nelfinavir
Danish: VIRACEPT 50 mg/g oralt pulver Nelfinavir
English: In a second study, healthy volunteers received single doses of 1250 mg VIRACEPT (5 x 250 mg tablets) under fasted or fed conditions (two meals with different fat content).
Danish: I et andet studie fik raske frivillige en enkeltdosis på 1250 mg VIRACEPT (5 x 250 mg tabletter) i fastende tilstand eller efter indtagelse af føde (to måltider med forskelligt fedtindhold).
English: Take special care with Viracept
Danish: Vær ekstra forsigtig med at tage Viracept
English: Nelfinavir is also an inhibitor of CYP 3A4.
Danish: Nelfinavir er også en hæmmer af CYP3A4.
English: • This medicine has been prescribed for you.
Danish: • Lægen har ordineret Viracept til dig personligt.
English: The median increase from baseline in CD4+ cell count over 48 weeks was 207 cells/mm3 and 203 cells/mm3 in the nelfinavir and fosamprenavir/ritonavir groups respectively.
Danish: Den mediane stigning fra baseline i CD4+ celletallet efter 48 uger var 207 celler/mm3 og 203 celler/mm3 for henholdsvis nelfinavir- og fosamprenavir/ritonavirgrupperne.
English: • You can mix the powder with a small amount of water, milk, baby formula, soy formula, soy milk, dietary liquid supplements or pudding.
Danish: • Du kan blande pulveret med lidt vand, mælk, modermælkserstatning, soja modermælkserstatning, sojamælk, flydende kosttilsskud eller budding.
English: Nelfinavir levels may increase on stopping St. John's wort, and the dose of nelfinavir may need adjusting.
Danish: Nelfinavirkoncentrationer kan stige ved ophør med perikon og det kan blive nødvendigt at justere dosis af nelfinavir.
English: You should monitor your child to assure that the recommended number of tablets are taken at each dose with meals, for each weight band.
Danish: Du skal sikre, at dit barn inden for de enkelte vægtintervaller får det anbefalede antal tabletter ved hvert måltid.
English: Dose to be given three times a day to children aged 3 to 13 Body weight of your child
Danish: Dosis som gives tre gange daglig til børn i alderen 3 til 13 år Dit barns kropsvægt
English: The efficacy of the BID (twice daily) regimen has been evaluated versus the TID (three times daily) regimen primarily in patients naïve to PIs (see section 5.1).
Danish: Effekten af et BID-regime (to gange daglig), sammenlignet med et TID-regime (3 gange daglig), er primært undersøgt hos patienter, som ikke tidligere har fået proteasehæmmere (se pkt.
English: Patients receiving VIRACEPT BID (n=10) achieved nelfinavir Cmax of 4.0 ± 0.8 µg/ml and morning and evening trough concentrations of 2.2 ± 1.3 µg/ml and 0.7 ± 0.4 µg/ml, respectively.
Danish: De patienter, der fik VIRACEPT to gange daglig (n=10) opnåede Cmax nelfinavir på 4,0 ± 0,8 μg/ml og trough-koncentrationer om morgenen og aftenen på hhv. 2,2 ± 1,3 μg/ml og 0,7 ± 0,4 μg/ml.
English: VIRACEPT 250 mg film-coated tablets Nelfinavir
Danish: VIRACEPT 250 mg filmovertrukne tabletter Nelfinavir
English: Patients with renal or hepatic impairment should not be given colchicine with nelfinavir (see section 4.4).
Danish: Patienter med nedsat nyre-eller leverfunktion bør ikke behandles med colchicin og nelfinavir samtidig (se pkt.
English: In one study, healthy volunteers received a single dose of 1250 mg of VIRACEPT (5x 250 mg tablets) under fasted or fed conditions (three meals with different caloric and fat contents).
Danish: I et studie fik raske frivillige en enkeltdosis på 1250 mg VIRACEPT (5 x 250 mg tabletter) i fastende tilstand eller efter indtagelse af føde (tre måltider med forskelligt kalorie- og fedtindhold).
English: Contraceptives with norethindrone should not be coadministered with nelfinavir.
Danish: Kontraceptiva med norethindron bør ikke administreres sammen med nelfinavir.
English: Omeprazole should not be coadministered with nelfinavir.
Danish: Omeprazol bør ikke administreres sammen med nelfinavir.
English: Vascular disorders: Rare (≥ 0.01 % - ≤ 0.1 %): increased spontaneous haemorrhage bleeding in patients with haemophilia.
Danish: Vaskulære sygdomme: Sjælden (≥ 0,01 % - ≤ 0,1 %): Øget spontan blødning hos patienter med hæmofili.
English: Number of scoops Blue Scoop
Danish: Antal måleskeer Blå måleske
English: Plasma levels of nelfinavir can be reduced by concomitant use of the herbal preparation St. John's wort (Hypericum perforatum).
Danish: Perikon (Hypericum perforatum) Plasmakoncentrationerne af nelfinavir kan reduceres ved samtidig brug af urtepræparatet perikon (Hypericum perforatum).
English: • Once the tablet is dispersed, mix the cloudy bluish liquid thoroughly and take immediately.
Danish: Når tabletten/tabletterne er opløst, skal den uklare, blålige væske omrøres grundigt og indtages med det samme.
English: What Viracept looks like and contents of the pack Viracept 50 mg/g oral powder is a white to off-white powder.
Danish: Viracept 50 mg/g oralt pulver er et hvidt til off-white pulver.
English: Contraceptives with ethinyl estradiol should not be coadministered with nelfinavir.
Danish: Kontraceptiva med ethinylestradiol bør ikke administreres sammen med nelfinavir.
English: Roche Pharma AG Emil-Barell-Str. 1
Danish: Emil- Barrell Strasse 1
English: Patients with renal impairment should not be given colchicine with VIRACEPT.
Danish: Patienter med nedsat nyrefunktion bør ikke gives colchicin sammen med VIRACEPT.
English: PDE-5 inhibitors for the treatment of pulmonary arterial hypertension (PAH) Tadalafil
Danish: PDE-5-hæmmere til behandling af pulmonal arteriel hypertension (PAH) Samtidig administration af
English: A pharmacokinetic study in HIV-positive patients compared multiple doses of 1250 mg twice daily (BID) with multiple doses of 750 mg three times daily (TID) for 28 days.
Danish: Et farmakokinetisk studie hos hiv-positive patienter sammenlignede 1250 mg to gange daglig med 750 mg tre gange daglig, begge i 28 dage.
English: Study M98-863 is a randomised, double blind trial of 653 antiretroviral-naïve patients investigating lopinavir/ritonavir (400/100 mg BID n=326) compared to nelfinavir (750 mg TID n=327), each in combination with lamivudine (150 mg twice daily) and stavudine (40 mg twice daily).
Danish: Studie M98-863 er en randomiseret, dobbeltblindet undersøgelse med 653 antiretroviralbehandlingsnaive patienter, hvor lopinavir/ritonavir (400/100 mg to gange daglig, n=326) blev sammenlignet med nelfinavir (750 mg tre gange daglig, n=327), begge i kombination med lamivudin (150 mg to gange daglig) og stavudin (40 mg to gange daglig).
English: Each film-coated tablet contains 250 mg of nelfinavir (as mesilate).
Danish: Hver filmovertrukken tablet indeholder 250 mg nelfinavir (som mesilat).
English: Each film-coated tablet contains 292.25 mg of nelfinavir mesilate, equivalent to 250 mg nelfinavir as free base.
Danish: Hver filmovertrukken tablet indeholder 292,25 mg nelfinavirmesilat svarende til 250 mg nelfinavir
English: Increase in AUC, Cmax and Tmax for Nelfinavir in Fed State Relative to Fasted State Following 1250 mg VIRACEPT (5 x 250 mg tablets)
Danish: Stigning i AUC, Cmax og Tmax for nelfinavir efter indtagelse af føde i forhold til fastende tilstand efter 1250 mg VIRACEPT (5 x 250 mg tabletter)
English: Concomitant use of rifampicin is contraindicated with nelfinavir
Danish: Samtidig brug af rifampicin og nelfinavir er kontraindiceret
English: NAME OF THE MEDICINAL PRODUCT VIRACEPT 250 mg film-coated tablets.
Danish: LÆGEMIDLETS NAVN VIRACEPT 250 mg filmovertrukne tabletter.
English: Saquinavir 1200 mg TID (nelfinavir 750 mg single dose)
Danish: Saquinavir 1200 mg 3 gange daglig (nelfinavir 750 mg enkeltdosis)
English: Rare (≥ 0.01 % - ≤ 0.1 %): abdominal distension,
Danish: Sjælden (≥ 0,01 % - ≤ 0,1 %): Oppustet mave.
English: Lipid disorders should be managed as clinically appropriate (see section 4.8).
Danish: Lipidsygdomme skal behandles i henhold til klinisk praksis (se pkt.
English: • Triazolam or oral midazolam taken by mouth (for anxiety or to help you sleep)
Danish: • Triazolam eller midazolam indtaget gennem munden (sovemedicin eller mod angst)
English: • Rinse the glass with a half cup of water and swallow the rinse to ensure all of the dose is taken.
Danish: • Skyl glasset med et halvt glas vand og drik vandet, som du har brugt til at skylle med, for at
English: Table 1 Dose to be taken by adults and children older than 13 years How often you take it
Danish: Tabel 1 Dosis som tages af voksne og børn ældre end 13 år
English: At 24 weeks, the percentage of patients whose plasma HIV RNA levels had decreased to below the limit of detection of the assay (< 400 copies/ml) were 81 % and 8 % for the groups treated with nelfinavir 750 mg TID plus zidovudine and lamivudine or zidovudine and lamivudine, respectively.
Danish: Efter 24 uger var der 81 % og 8 % af patienterne, hvis plasma-hiv-RNA var faldet til under prøvens detektionsgrænse (< 400 kopier/ml) i hhv. gruppen, der fik 750 mg nelfinavir 3 gange daglig sammen med zidovudin og lamivudin, og gruppen der fik zidovudin og lamivudin.
English: Measure out a level scoop of powder.
Danish: Afmål en strøgen skefuld pulver.
English: Uncommon (≥ 0.1 % - ≤ 1 %): hypersensitivity including bronchospasm, pyrexia, pruritus, facial oedema and rash maculo-papular or dermatitis bullous.
Danish: Ikke almindelig (≥ 0,1 % - ≤ 1 %): Overfølsomhed inklusive bronkospasme, pyreksi, kløe, ansigtsødem og makulopapulær udslæt eller bulløs dermatitis.
English: Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltese insufficiency should not take this medicine.
Danish: VIRACEPT oralt pulver indeholder også saccharose og bør ikke anvendes til patienter med arvelig fructoseintolerans, glucose/galactosemalabsorption eller sucrase-isomaltasemangel.
English: Patients aged 3 to 13 years: for children, the recommended starting dose is 50-55 mg/kg BID or, if using a TID regimen, 25 - 35 mg/kg body weight per dose.
Danish: Patienter mellem 3 og 13 år: Den anbefalede initiale dosis til børn er 50-55 mg/kg to gange daglig eller 25-35 mg/kg legemsvægt indgivet tre gange daglig.
English: The mean increase from baseline in CD4+ cell count at week 48 was 195 cells/mm3 and 207 cells/mm3 in the nelfinavir and lopinavir/ritonavir groups respectively.
Danish: Den gennemsnitlige stigning fra baseline i CD4+ celletallet efter 48 uger var henholdsvis 195 celler/mm3 og 207 celler/mm3 i nelfinavir- og lopinavir/ritonavirgrupperne.
English: Proton Pump Inhibitors Omeprazole 20 mg bid x 4 days administered 30 minutes before nelfinavir (Nelfinavir 1250 mg bid x 4 days)
Danish: Syrepumpehæmmere Omeprazol 20 mg 2 gange daglig i 4 dage administreret 30 minutter før nelfinavir (Nelfinavir 1250 mg 2 gange daglig i 4 dage)
English: Each gram of oral powder contains 50 mg of nelfinavir (as mesilate).
Danish: Hvert gram oralt pulver indeholder 50 mg nelfinavir (som mesilat).
English: Indinavir 800 mg Q8H X 7 days (nelfinavir 750 mg single dose)
Danish: Indinavir 800 mg hver 8. time i 7 dage (nelfinavir 750 mg enkeltdosis)
English: Patients aged 3 to 13 years: for children, the recommended starting dose is 50-55 mg/kg BID or if using a TID regimen, 25 - 35 mg/kg body weight per dose.
Danish: Patienter mellem 3 og 13 år: Den anbefalede initiale dosis til børn er 50-55 mg/kg per dosis to gange daglig eller 25-35 mg/kg per dosis tre gange daglig.
English: Atorvastatin is less dependent on CYP3A4 for metabolism.
Danish: Atorvastatins metabolisme er mindre afhængig af CYP3A4.
English: If you want to take the tablets instead please see the Package Leaflet for Viracept 250 mg tablets.
Danish: Hvis du vil tage tabletter i stedet for, så se indlægssedlen for Viracept
English: Viracept is used with other ‘anti-retroviral' medicines to:
Danish: Viracept anvendes sammen med andre antiretrovirale lægemidler for at: • Bekæmpe hiv (human immundefekt virus).
English: The signs may include difficulty in breathing, fever, itching, swelling of the face and skin rashes that can sometimes form blisters.
Danish: opsvulmet ansigt samt hududslæt, der i nogle tilfælde kan danne blister.
English: Metabolic enzyme inducers: Potent inducers of CYP3A4 (e.g., rifampicin, pehnobarbital and carbamazepine) may reduce nelfianvir plasma concentrations and their coadministration is contraindicated (see section 4.3).
Danish: Metaboliske enzyminduktorer: Potente induktorer af CYP3A4 (f.eks. rifampicin, phenobarbital og carbamazepin) kan reducere nelfinavirs plasmakoncentration, og derfor er samtidig brug kontraindiceret (se pkt 4.3).
English: Increase in Nelfinavir AUC, Cmax and Tmax in Fed Low Fat (20%) versus High fat (50%) State Relative to Fasted State Following 1250 mg VIRACEPT (5 x 250 mg tablets) Number of
Danish: Stigning i AUC, Cmax og Tmax for nelfinavir efter indtagelse af føde med lavt fedtindhold (20 %) versus højt fedtindhold (50 %) i forhold til fastende tilstand efter 1250 mg VIRACEPT (5 x 250 mg tabletter)
English: The table provides a schedule assuring that the appropriate total daily dose of Viracept is taken each day based on the child's weight.
Danish: Tabellen giver ud fra barnets vægt en doseringsplan, der sikrer, at en passende totaldosis af Viracept indtages hver dag.
English: Use with increased monitoring for adverse events associated with increased exposure to vardenafil.
Danish: Kan anvendes under nøje overvågning for bivirkninger forbundet med øget eksponering for vardenafil.
English: What Viracept contains
Danish: Viracept indeholder:
English: Concomitant use of fluticasone propionate and VIRACEPT may increase plasma concentrations of fluticasone propionate.
Danish: Samtidig brug af fluticasonpropionat og VIRACEPT kan øge plasmakoncentrationen af fluticasonpropionat.
English: In vivo: The overall incidence of the D30N mutation in the viral protease of assessable isolates (n=157) from patients receiving nelfinavir monotherapy or nelfinavir in combination with zidovudine and lamivudine or stavudine was 54.8 %.
Danish: In vivo: Hos patienter, der fik nelfinavir-monoterapi eller nelfinavir i kombination med zidovudin og lamivudin eller stavudin, var den overordnede hyppighed af D30N-mutationer i den virale protease hos vurderbare isolater (n=157) 54,8 %.
English: Each gram of oral powder contains an amount of nelfinavir mesilate that makes 50 mg of nelfinavir.
Danish: Hvert gram oralt pulver indeholder en mængde af nelfinavirmesilat, som svarer til 50 mg nelfinavir.
English: Each gram of oral powder contains nelfinavir mesilate corresponding to 50 mg of nelfinavir.
Danish: Hvert gram oralt pulver indeholder nelfinavirmesilat svarende til 50 mg nelfinavir.
English: The length of combination anti-retroviral therapy, corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index, among others, may be some of the many risk factors for developing this disease.
Danish: Nogle af de mange risikofaktorer for udvikling af denne sygdom kan blandt andet være varigheden af den antiretrovirale kombinationsbehandling, steroidbehandling, alkoholforbrug, alvorligt nedsat immunforsvar samt højere body mass index (BMI).
English: • Combination anti-retroviral therapy may also cause raised lactic acid and sugar in the blood,
Danish: • Antiretroviral kombinationsbehandling kan også forårsage forhøjet mælkesyre og sukker i blodet, hyperlipidæmi (øget fedt i blodet) og resistens mod insulin.
English: Acidic food or juice (e.g., orange juice, apple juice or apple sauce) are not recommended to be used in combination with VIRACEPT, because the combination may result in a bitter taste.
Danish: Det anbefales ikke at bruge syreholdig føde eller juice (som f.eks. appelsinjuice, æblejuice eller æblemos) i kombination med Viracept, idet kombinationen kan give en bitter smag.
English: Concomitant use of trazodone and nelfinavir may increase plasma concentrations of trazodone and a lower dose of trazodone should be considered.
Danish: Samtidig brug af trazodon og nelfinavir kan øge plasmakoncentrationen af trazodon, og en lavere
English: Acidic food or juice (e.g. orange juice, apple juice or apple sauce) are not recommended to be used in combination with VIRACEPT, because the combination may result in a bitter taste.
Danish: Det anbefales ikke at bruge syreholdig føde eller juice (som f.eks. appelsinjuice, æblejuice eller æblemos) i kombination med VIRACEPT, idet kombinationen kan give en bitter smag.
English: • Any other medicines for HIV infection such as ritonavir, indinavir, saquinavir and delavirdine,
Danish: Fortæl din læge eller på apoteket, hvis du tager nogle af de nedenstående lægemidler: • Andre lægemidler mod hiv-infektion såsom ritonavir, indinavir, saquinavir og delavirdin,
English: HOW TO TAKE VIRACEPT
Danish: SÅDAN SKAL DU TAGE VIRACEPT
English: Norethindrone AUC ↓18% Nelfinavir concentrations not measured
Danish: Ethinylestradiol AUC ↓ 47 % Nelfinavirkoncentrationer er ikke målt
English: Use with increased monitoring for adverse events associated with increased exposure to tadalafil.
Danish: Kan anvendes under nøje overvågning for bivirkninger forbundet med øget eksponering for tadalafil.
English: Renal Impairment: Since nelfinavir is highly bound to plasma proteins, it is unlikely that it will be significantly removed by haemodiaylisis or peritoneal dialysis.
Danish: Nedsat nyrefunktion: Det er usandsynligt at nelfinavir vil fjernes signifikant ved hæmodialyse eller peritoneal dialyse, da nelfinavir i høj grad er bundet til plasmaproteiner.
English: Coadministration of nelfinavir with fluticasone proprionate may increase plasma concentrations of fluticasone propionate.
Danish: Samtidig administration af nelfinavir og fluticasonpropionat kan øge plasmakoncentrationen af fluticasonpropionat.
English: Acidic food or juice (such as orange juice, apple juice or apple sauce) are not recommended to be taken with Viracept because together they may have a bitter taste.
Danish: Det anbefales ikke at bruge syreholdig føde eller juice (som f.eks. appelsinjuice, æblejuice eller æblemos) i sammen med VIRACEPT, idet kombinationen kan give en bitter smag.
English: Dosing Regimen1 N2
Danish: Dosering1
English: INSTRUCTIONS ON USE
Danish: Samtidig brug af
English: Patients with haemophilia: There have been reports of increased bleeding, including spontaneous skin haematomas and haemarthroses, in haemophiliac patients type A and B treated with PIs.
Danish: Patienter med hæmofili: For patienter med hæmofili type A og B, som er under behandling med proteasehæmmere er der rapporteret øget blødning, herunder spontane hudblødninger og ledblødninger.
English: Study APV30002 is a randomised, open-label trial of 649 antiretroviral treatment naïve patients with advanced HIV-disease, investigating fosamprenavir/ritonavir (1400 mg/200 mg QD n=322) compared to nelfinavir (1250 mg BID n=327), each in combination with lamivudine (150 mg twice daily) and abacavir (300 mg twice daily).
Danish: Studie APV3002 er en randomiseret, åben undersøgelse med 649 antiretroviral-behandlingsnaive patienter med fremskreden hiv-sygdom, hvor fosamprenavir/ritonavir (1400 mg/200 mg én gang daglig, n=322) blev sammenlignet med nelfinavir (1250 mg to gange daglig, n=327), i begge tilfælde kombineret med lamivudin (150 mg to gange daglig) og abacavir (300 mg to gange daglig).
English: Dosage reduction of rifabutin to 150 mg QD is necessary when nelfinavir 750 mg TID or 1250 mg BID and rifabutin are co-administered.
Danish: Det er nødvendigt at nedsætte dosering af rifabutin til 150 mg 1 gang daglig, når det indgives sammen med nelfinavir 750 mg 3 gange daglig eller 1250 mg 2 gange daglig.
English: • Alfuzosin (for benign prostatic hyperplasia (BPH))
Danish: • Alfuzosin (mod forstørret blærehalskirtel (prostata))