FrancophonIA/ELRC3.0 huggingface dataset:
English: Each tablet contains 96 mg lactose monohydrate.
Slovenian: Ena tableta vsebuje 96 mg laktoze monohidrata.
English: • this may cause the child to be tired or breathless
Slovenian: • To lahko povzroči utrujenost ali zasoplost otroka.
English: Truvada should not be given to adolescents with existing kidney problems.
Slovenian: Zdravila Truvada se ne sme dajati mladostnikom z obstoječimi ledvičnimi težavami.
English: The time to onset of protection after commencing Truvada is unknown.
Slovenian: Čas do začetka zaščite po uvedbi zdravila Truvada ni znan.
English: • Reminder to attend scheduled clinic visits.
Slovenian: • opozorila za načrtovane obiske pri zdravniku.
English: The most frequent adverse reaction reported in the Truvada group in the iPrEx study was headache (1%).
Slovenian: Najpogostejši neželeni učinek, o katerem so poročali v skupini, ki je prejemala zdravilo Truvada v študiji iPrEx, je bil glavobol (1 %).
English: These may be signs of HIV infection:
Slovenian: Možni znaki okužbe s HIV:
English: • If you have hepatitis B, it is especially important not to stop your Truvada treatment without talking to your doctor first.
Slovenian: • Če ste okuženi s hepatitisom B, je še zlasti pomembno, da ne prenehate z zdravljenjem z zdravilom Truvada, ne da bi se prej posvetovali z zdravnikom.
English: • Know your hepatitis B virus (HBV) infection status before starting Truvada.
Slovenian: • Ugotovite stanje okužbe z virusom hepatitisa B (HBV) pred začetkom jemanja zdravila Truvada.
English: • weakness beginning in the hands and feet and moving up towards the trunk of the body
Slovenian: • oslabelost, ki se najprej pojavi v dlaneh in stopalih in se nato širi proti trupu
English: • If you become pregnant, or plan to become pregnant, ask your doctor about the potential benefits and risks of therapy with Truvada to you and your child.
Slovenian: • Če zanosite ali načrtujete zanositev, se posvetujte z zdravnikom o možnih koristih in tveganjih zdravljenja z zdravilom Truvada za vas in vašega otroka.
English: Truvada should only be used in individuals with creatinine clearance (CrCl) < 80 mL/min if the potential benefits are considered to outweigh the potential risks.
Slovenian: Zdravilo Truvada se sme uporabljati samo pri posameznikih z očistkom kreatinina (CrCl) < 80 ml/min, če se oceni, da morebitne koristi odtehtajo morebitna tveganja.
English: Truvada should only be used for pre-exposure prophylaxis as part of an overall HIV-1 infection prevention strategy including the use of other HIV-1 prevention measures (e.g. consistent and correct condom use, knowledge of HIV-1 status, regular testing for other sexually transmitted infections).
Slovenian: Zdravilo Truvada se sme uporabljati samo za zaščito pred izpostavitvijo kot del splošne strategije za preprečevanje okužbe s HIV-1, vključno z uporabo drugih ukrepov za preprečevanje HIV-1 (npr. dosledna in pravilna uporaba kondomov, zavedanje statusa okužbe s HIV-1, redno testiranje za druge spolno prenosljive okužbe).
English: If you have kidney problems, your doctor may advise you to stop taking Truvada or, if you already have HIV, to take Truvada less frequently.
Slovenian: Če imate ledvične težave, vam zdravnik lahko svetuje, da zdravilo Truvada prenehate jemati ali, če ste že okuženi s HIV, da zdravilo Truvada uporabljate manj pogosto.
English: Truvada is not always effective in preventing the acquisition of HIV-1.
Slovenian: Zdravilo Truvada ni vedno učinkovito pri preprečevanju okužbe s HIV-1.
English: BMD Z-scores were not adjusted for height and weight.
Slovenian: Z-vrednost MGK ni bila prilagojena za višino in telesno maso.
English: Therefore, the same problems may be seen if Truvada is administered with a third nucleoside analogue.
Slovenian: Zato je možno, da se bodo enake težave pojavile pri jemanju zdravila Truvada s tretjim analogom nukleozidov.
English: Do not take Truvada to reduce your risk unless you are confirmed to be HIV negative.
Slovenian: Zdravila Truvada ne jemljite za zmanjšanje tveganja, razen če je potrjeno, da ste HIV negativni.
English: Tenofovir is primarily excreted by the kidney by both filtration and an active tubular transport system with approximately 70-80% of the dose excreted unchanged in urine following intravenous administration.
Slovenian: Tenofovir se primarno izloča preko ledvic tako s filtracijo kot z aktivnim tubularnim transportnim sistemom, pri čemer se po intravenskem vnosu približno 70-80% odmerka izloči nespremenjenega z urinom.
English: Individuals over the age of 65 years are more likely to have decreased renal function, therefore caution should be exercised when administering Truvada to older people.
Slovenian: Obstaja večja verjetnost, da je ledvična funkcija pri posameznikih, starejših od 65 let, zmanjšana, zato je pri dajanju zdravila Truvada starejšim ljudem potrebna previdnost.
English: If you feel dizzy while taking Truvada, do not drive and do not use any tools or machines.
Slovenian: Če se vam v času zdravljenja z zdravilom Truvada pojavlja omotičnost, ne vozite avtomobila in ne upravljajte z orodji ali stroji.
English: If you have taken Truvada during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Slovenian: Če ste zdravilo Truvada jemali med nosečnostjo, vas lahko zdravnik naroči na redne preiskave krvi in druge diagnostične preiskave, da bo spremljal razvoj vašega otroka.
English: In order to optimise the absorption of tenofovir, it is recommended that Truvada should preferably be taken with food.
Slovenian: Za optimalno absorpcijo tenofovirja se priporoča zdravilo Truvada jemati s hrano.
English: o Do not share or re-use needles or other injection or drug equipment.
Slovenian: o Ne delite ali ponovno uporabljajte igel ali drugih pripomočkov za injiciranje in za ostale oblike jemanja drog.
English: In addition, the clinical response to treatment should be closely monitored in patients receiving Truvada at a prolonged dosing interval.
Slovenian: Poleg tega je treba skrbno spremljati klinični odziv na zdravljenje pri bolnikih, ki prejemajo zdravilo Truvada s podaljšanim intervalom med odmerki.
English: o Do not share personal items that can have blood or body fluids on them, such as toothbrushes and razor blades.
Slovenian: o Ne delite osebnih predmetov, na katerih so lahko kri ali telesne tekočine, kot so zobne ščetke in brivniki.
English: If you take more Truvada than you should
Slovenian: Če ste vzeli večji odmerek zdravila Truvada, kot bi smeli
English: − Truvada should always be used combined with other medicines to treat HIV infection.
Slovenian: ­ Zdravilo Truvada je treba vedno uporabljati v kombinaciji z drugimi zdravili za zdravljenje okužbe z virusom HIV.
English: EU/1/04/305/001 30 film-coated tablets EU/1/04/305/002 90 (3 x 30) film-coated tablets
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/04/305/001 30 filmsko obloženih tablet EU/1/04/305/002 90 (3 x 30) filmsko obloženih tablet
English: If clinical symptoms consistent with acute viral infection are present and recent (< 1 month) exposures to HIV-1 are suspected, use of Truvada should be delayed for at least one month and HIV-1 status reconfirmed before starting Truvada for pre-exposure prophylaxis.
Slovenian: Če so prisotni klinični simptomi akutne virusne okužbe in obstaja sum na nedavno (< 1 mesec) izpostavljenost virusu HIV-1, je treba uporabo zdravila Truvada zamakniti za najmanj en mesec in ponovno potrditi stanje okužbe s HIV-1, preden se začne zdravilo Truvada jemati za zaščito pred izpostavitvijo.
English: Patients infected with HBV who discontinue Truvada should be closely monitored with both clinical and laboratory follow-up for at least several months after stopping treatment.
Slovenian: Bolniki z okužbo s HBV, ki prekinejo zdravljenje z zdravilom Truvada, potrebujejo natančno spremljanje z ustreznimi kliničnimi in laboratorijskimi preiskavami še vsaj nekaj mesecev po prenehanju zdravljenja.
English: • If you are being treated for HIV infection your doctor will prescribe Truvada with other antiretroviral medicines.
Slovenian: • Če se zdravite zaradi okužbe s HIV, vam bo zdravnik predpisal zdravilo Truvada skupaj z drugimi protiretrovirusnimi zdravili.
English: Contains lactose monohydrate, see leaflet for further information.
Slovenian: SEZNAM POMOŽNIH SNOVI Vsebuje laktozo monohidrat, za dodatne informacije glejte navodilo za uporabo.
English: • Children given emtricitabine very commonly experienced changes in skin colour including
Slovenian: • Otroci, ki so dobivali emtricitabin, so imeli zelo pogosto spremembe obarvanosti kože,
English: You do not need to take another tablet if you were sick more than 1 hour after taking Truvada.
Slovenian: Še ene tablete vam ni treba vzeti, če ste bruhali več kot 1 uro po zaužitju zdravila Truvada.
English: It is important not to miss a dose of Truvada.
Slovenian: Pomembno je, da ne izpustite nobenega odmerka zdravila Truvada.
English: When using Truvada for pre-exposure prophylaxis individuals should be reassessed at each visit to ascertain whether they remain at high risk of HIV-1 infection.
Slovenian: Pri uporabi zdravila Truvada pri posameznikih za zaščito pred izpostavitvijo je treba ob vsakem obisku ponovno oceniti, ali so še vedno močno izpostavljeni tveganju za okužbo z virusom HIV-1.
English: Do not miss any doses of Truvada, or stop taking it.
Slovenian: Ne izpustite nobenega odmerka zdravila Truvada in ga ne prenehajte jemati.
English: Table 2: Interactions between Truvada or its individual component(s) and other medicinal products
Slovenian: Preglednica 2: Interakcije med zdravilom Truvada ali njegovo(-imi) posamično(-imi) učinkovino(-ami) in drugimi zdravili
English: • If you notice within 12 hours of the time you usually take Truvada, take the tablet preferably with food as soon as possible.
Slovenian: • Če to opazite v roku 12 ur od časa, ko običajno vzamete zdravilo Truvada, morate tableto vzeti čim prej, najbolje s hrano.
English: Pharmacokinetic studies have not been performed with Truvada in children and adolescents (under 18 years of age).
Slovenian: Farmakokinetične študije z zdravilom Truvada niso bile izvedene pri otrocih in mladostnikih (mlajših od 18 let).
English: If you accidentally take more than the recommended dose of Truvada, contact your doctor or nearest emergency department for advice.
Slovenian: Če ste pomotoma zaužili odmerek zdravila Truvada, višji od priporočenega, se posvetujte z zdravnikom ali poiščite najbližjo urgentno ambulanto.
English: HIV-1 uninfected individuals should be counselled at frequent intervals to strictly adhere to the recommended Truvada daily dosing schedule.
Slovenian: Posamezniki, ki niso okuženi s HIV-1, potrebujejo svetovanje v pogostih intervalih za strogo upoštevanje priporočenega režima dnevnega odmerjanja zdravila Truvada.
English: • Truvada may affect your kidneys.
Slovenian: • Zdravilo Truvada lahko vpliva na ledvice.
English: Interrupting use of Truvada should also be considered in case of progressive decline of renal function when no other cause has been identified.
Slovenian: O prekinitvi uporabe zdravila Truvada je treba razmisliti tudi v primeru progresivnega upada ledvične funkcije, če ni bil ugotovljen noben drug razlog.
English: Discontinuation of Truvada therapy in patients infected with HBV may be associated with severe acute exacerbations of hepatitis.
Slovenian: Prekinitev zdravljenja z zdravilom Truvada pri bolnikih z okužbo s HBV je lahko povezana s hudimi akutnimi poslabšanji hepatitisa.
English: Serum Herpes Simplex Virus Type 2 Infection, N (%) Urine Leukocyte Esterase Positive, N (%)
Slovenian: Serumska okužba z virusom herpes simpleksa tipa 2, N (%) Pozitivna prisotnost levkocita esteraza v urinu, N (%)
English: Limited data from clinical studies support once daily dosing in HIV-1 uninfected individuals with CrCl 60-80 mL/min.
Slovenian: Omejeno število podatkov iz kliničnih študij podpira odmerjanje enkrat dnevno pri posameznikih, ki niso okuženi s HIV-1, s CrCl 6080 ml/min.
English: The Marketing Authorisation Holder (MAH) shall ensure that all physicians who are expected to prescribe/use Truvada in either adolescent patients for the treatment of HIV-1 infection or in adults and adolescents for PrEP are provided with a physician educational pack containing the Summary of Product Characteristics and an appropriate educational brochure, as detailed below:
Slovenian: Imetnik dovoljenja za promet z zdravilom zagotovi, da vsi zdravniki, ki naj bi predpisovali/uporabljali zdravilo Truvada za zdravljenje mladostnikov, okuženih z virusom HIV-1, ali za PrEP pri odraslih in mladostnikih, prejmejo izobraževalni paket za zdravnike, ki vsebuje Povzetek glavnih značilnosti zdravila in ustrezno izobraževalno gradivo, kot je navedeno v nadaljevanju:
English: While taking Truvada you may still develop infections or other illnesses associated with HIV infection.
Slovenian: Med jemanjem zdravila Truvada lahko še vedno pride do okužbe ali drugih bolezni, povezane z okužbo s HIV.
English: • That there is an increased risk of renal disease in HIV infected patients associated with tenofovir disoproxil fumarate-containing products such as Truvada
Slovenian: • da obstaja povečano tveganje za ledvično bolezen pri bolnikih s HIV, povezano z zdravili, ki vsebujejo dizoproksiltenofovirijev fumarat, kot je zdravilo Truvada;
English: Truvada has not been studied in HIV-1 uninfected individuals with creatinine clearance < 60 mL/min and is therefore not recommended for use in this population.
Slovenian: Zdravilo Truvada ni bilo preučevano pri posameznikih, ki niso okuženi s HIV-1, z očistkom kreatinina < 60 ml/min in se zato ne priporoča za uporabo pri tej populaciji.
English: (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100) or rare (≥ 1/10,000 to
Slovenian: Pogostnost je definirana kot zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100) ali redki neželeni učinki (≥ 1/10.000 do < 1/1.000).
English: Truvada film-coated tablets are blue, capsule-shaped tablets, engraved on one side with the word “GILEAD” and on the other side with the number “701”.
Slovenian: Truvada filmsko obložene tablete so modre tablete kapsulne oblike z vtisnjeno besedo “GILEAD” na eni strani in številko “701” na drugi strani.
English: • Just taking Truvada may not stop you getting HIV.
Slovenian: • Samo jemanje zdravila Truvada morda ne bo preprečilo okužbe s HIV.
English: Truvada is not recommended if you have severe kidney disease or are on dialysis.
Slovenian: Uporaba zdravila Truvada ni priporočljiva, če imate hudo ledvično obolenje ali ste na dializi.
English: a Relative risk reduction calculated for mITT cohort based on incident (post-baseline) seroconversion.
Slovenian: a Relativno zmanjšanje tveganja, izračunano za mITT kohorto na podlagi dogodka serokonverzije (po izhodišču).
English: What Truvada is and what it is used for What you need to know before you take Truvada How to take Truvada
Slovenian: Kaj je zdravilo Truvada in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Truvada Kako jemati zdravilo Truvada Možni neželeni učinki
English: • That Truvada may cause a reduction in BMD and the effects of Truvada associated changes in BMD on long-term bone health and future fracture risk are currently unknown in paediatric patients
Slovenian: • da lahko zdravilo Truvada vpliva na zmanjšanje MKG in da spremembe MKG zaradi učinkov zdravila Truvada na dolgoročno zdravje kosti in prihodnje tveganje zlomov pri pediatričnih bolnikih trenutno niso znani;
English: Administration of Truvada with food resulted in a delay of approximately three quarters of an hour in reaching maximum tenofovir concentrations and increases in tenofovir AUC and Cmax of approximately 35% and 15%, respectively, when administered with a high fat or light meal, compared to administration in the fasted state.
Slovenian: Jemanje zdravila Truvada s hrano je povzročilo približno tričetrturno zakasnitev pri doseganju maksimalne koncentracije tenofovirja ter povečanju AUC tenofovirja za približno 35% in Cmax za približno 15% pri jemanju skupaj z obrokom, bogatim z maščobami ali lažjim obrokom, v primerjavi z jemanjem na tešče.
English: The safety and efficacy of Truvada in children under the age of 12 years have not been established (see section 5.2).
Slovenian: Varnost in učinkovitost zdravila Truvada pri otrocih, mlajših od 12 let, nista bili dokazani (glejte poglavje 5.2).
English: Blue, capsule-shaped, film-coated tablet, of dimensions 19 mm x 8.5 mm, debossed on one side with “GILEAD” and on the other side with “701”.
Slovenian: Modra, filmsko obložena tableta kapsulne oblike, z dimenzijami 19 mm x 8,5 mm, z vtisnjenima znakoma “GILEAD” na eni strani in “701” na drugi strani.
English: The frequency category was estimated from a statistical calculation based on the total number of patients exposed to emtricitabine in randomised controlled clinical studies (n = 1,563) or tenofovir disoproxil in randomised controlled clinical studies and the expanded access program (n = 7,319).
Slovenian: Kategorija pogostnosti je bila ocenjena s statističnim izračunom na podlagi skupnega števila bolnikov, izpostavljenih emtricatibinu v randomiziranih kontroliranih kliničnih študijah (n = 1 563) ali dizoproksiltenofoviratu v randomiziranih kontroliranih kliničnih študijah in podaljšanem programa dostopanja (n = 7 319).
English: The use of Truvada is not recommended in patients with severe renal impairment (creatinine clearance < 30 mL/min) and in patients who require haemodialysis since appropriate dose reductions cannot be achieved with the combination tablet (see sections 4.2 and 5.2).
Slovenian: Uporaba zdravila Truvada se ne priporoča pri bolnikih s hudo ledvično okvaro (očistek kreatinina < 30 ml/min) in bolnikih, ki potrebujejo hemodializo, ker ustreznega zmanjšanja odmerka ni mogoče doseči s kombinirano tableto (glejte poglavji 4.2 in 5.2).
English: • If you notice 12 hours or more after the time you usually take Truvada, forget about the missed dose.
Slovenian: • Če to opazite po 12 urah ali več od časa, ko običajno vzamete zdravilo Truvada, pozabljenega odmerka ne vzemite.
English: Truvada can only help reduce your risk of getting HIV before you are infected.
Slovenian: Zdravilo Truvada lahko samo pomaga zmanjšati tveganje za okužbo z virusom HIV, preden se okužite.
English: At baseline the randomised groups had similar median plasma HIV-1 RNA (5.02 and 5.00 log10 copies/mL) and CD4 counts (233 and 241 cells/mm3).
Slovenian: Ob izhodišču so imele randomizirane skupine podobno mediano števila HIV-1 RNA v plazmi (5,02 in 5,00 log10 kopij/ml) in CD4 (233 in 241 celic/mm3).
English: o Always practice safer sex. Use condoms to reduce contact with semen, vaginal fluids, or blood.
Slovenian: Uporabljajte kondome, da zmanjšate stik s semensko tekočino, vaginalnimi izločki ali krvjo.
English: The risk of HIV-1 infection should be balanced against the potential for renal and bone effects with long-term use of Truvada.
Slovenian: Tveganje za okužbo z virusom HIV-1 je treba presoditi glede na možne učinke na ledvice in kosti pri dolgotrajni uporabi zdravila Truvada.
English: A multidisciplinary approach is recommended to weigh the benefit/risk balance of the use of Truvada for the treatment of HIV-1 infection or for pre-exposure prophylaxis, decide the appropriate monitoring during treatment (including decision for treatment withdrawal) and consider the need for supplementation on a case by case basis.
Slovenian: Priporoča se multidisciplinarni pristop, s katerim se presodi o razmerju med koristmi in tveganji zdravljenja okužbe z virusom HIV-1 ali zaščite neokuženih mladostnikov pred izpostavitvijo z zdravilom Truvada, in sprejme odločitev glede ustreznega spremljanja med zdravljenjem (vključno z odločitvijo o prenehanju zdravljenja) ter razmisli o potrebi po dodatnem zdravljenju za vsakega posameznega bolnika.
English: Prior to initiating Truvada for the treatment of HIV-1 infection or for use in pre-exposure prophylaxis, it is recommended that creatinine clearance is calculated in all individuals.
Slovenian: Pred začetkom zdravljenja z zdravilom Truvada za zdravljenje okužbe s HIV-1 ali za uporabo za zaščito pred izpostavitvijo se priporoča izračun očistka kreatinina pri vseh posameznikih.
English: Pre-exposure prophylaxis: No new adverse reactions to Truvada were identified from two randomised placebo-controlled studies (iPrEx, Partners PrEP) in which 2,830 HIV-1 uninfected adults received Truvada once daily for pre-exposure prophylaxis.
Slovenian: Zaščita pred izpostavitvijo: Za zdravilo Truvada niso bili ugotovljeni nobeni novi neželeni učinki v dveh randomiziranih, s placebom nadzorovanih študijah (iPrEx, Partners PrEP), v katerih je 2.830 odraslih, ki niso bili okuženi s HIV-1, prejemalo zdravilo Truvada enkrat na dan za zaščito pred izpostavitvijo.
English: The safety and efficacy of Truvada for pre-exposure prophylaxis in patients with HBV or HCV infection has not been established.
Slovenian: Varnost in učinkovitost zdravila Truvada za zaščito pred izpostavitvijo pri bolnikih z okužbo z virusom HBV ali HCV nista bili ugotovljeni.
English: Therefore, a careful benefit-risk assessment is needed when Truvada is used in patients with creatinine clearance < 60 mL/min, and renal function should be closely monitored.
Slovenian: Zato je treba skrbno oceniti razmerje med koristmi in tveganjem pri uporabi zdravila Truvada pri bolnikih z očistkom kreatinina < 60 ml/min in skrbno spremljati delovanje ledvic.
English: However, in some HIV-1 infected patients, declines in creatinine clearance did not completely resolve despite tenofovir disoproxil discontinuation.
Slovenian: Vendar pa pri nekaterih bolnikih s HIV1 upad očistka kreatinina ni povsem izzvenel kljub prekinitvi zdravljenja z dizoproksiltenofoviratom.
English: • increased creatine kinase
Slovenian: • povišanje kreatin-kinaze
English: 8% (-1% to 17%)
Slovenian: 8% (-1% do 17%)
English: Truvada comes in bottles of 30 tablets.
Slovenian: Zdravilo Truvada je na voljo v plastenkah po 30 tablet.
English: The safety and efficacy of Truvada in children under the age of 12 years have not been established.
Slovenian: Varnost in učinkovitost zdravila Truvada pri otrocih, starih manj kot 12 let, nista bili dokazani.
English: Difference (95%CI)
Slovenian: Razlika (95% IZ)
English: Renal function (creatinine clearance and serum phosphate) should be evaluated prior to initiating Truvada for treatment of HIV-1 or for pre-exposure prophylaxis, and should be monitored during use as in adults (see above).
Slovenian: Ledvično funkcijo (očistek kreatinina in serumski fosfat) je treba pred uvedbo zdravila Truvada za zdravljenje okužbe s HIV-1 ali zaščite pred izpostavitvijo ovrednotiti, nato pa jo je treba med uporabo spremljati kot pri odraslih osebah (glejte zgoraj).
English: Some patients taking combination antiretroviral medicines such as Truvada may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Slovenian: Pri nekaterih bolnikih, ki jemljejo kombinirana protiretrovirusna zdravila, kot je zdravilo Truvada, se lahko pojavi bolezen kosti, imenovana osteonekroza (odmiranje kostnega tkiva zaradi nezadostne prekrvitve kosti).
English: Truvada P-valuea, b mITT Analysis
Slovenian: Placebo Truvada P-vrednosta, b
English: No human data on the effect of Truvada are available.
Slovenian: Ni podatkov o učinkih zdravila Truvada za ljudi.
English: The increased dose interval for Truvada in HIV-1 infected patients with moderate renal impairment is expected to result in higher peak plasma concentrations and lower Cmin levels as compared to patients with normal renal function.
Slovenian: Pričakuje se, da se bo odmerjanje zdravila Truvada v daljših časovnih intervalih za bolnike s HIV-1 z zmerno ledvično okvaro odražalo v višjih maksimalnih plazemskih koncentracijah in nižjih nivojih Cmin v primerjavi z bolniki z normalno ledvično funkcijo.
English: In vitro binding of emtricitabine to human plasma proteins was < 4% and independent of concentration over the range of 0.02 to 200 µg/mL.
Slovenian: In vitro je bila vezava emtricitabina na humane plazemske proteine manj kot 4% in je neodvisna od koncentracije v razponu med 0,02 in 200 µg/ml.