FrancophonIA/ELRC3.0 huggingface dataset:
English: Concomitant administration of 40 mg esomeprazole resulted in a 13% increase in trough plasma levels of phenytoin in epileptic patients.
Maltese: L-għoti konkomitanti ta' 40 mg ta' esomeprazole wassal għal żieda ta' 13% fil-livelli l-aktar baxxi ta' phenytoin fil-plasma f'pazjenti epilettiċi.
English: The co-administration of omeprazole (20 mg once a day) with atazanavir 400 mg/ritonavir 100 mg to healthy volunteers resulted in a decrease of approximately 30% in the atazanavir exposure as compared with the exposure observed with atazanavir 300 mg/ritonavir 100 mg once a day without omeprazole 20 mg once a day.
Maltese: L-għoti flimkien ta' omeprazole (20 mg darba kuljum) ma' atazanavir 400 mg/ritonavir 100 mg lil voluntiera b'saħħithom wassal għal tnaqqis ta' madwar 30% fl-espożizzjoni għal atazanavir meta mqabbel mal-espożizzjoni osservata b'atazanavir 300 mg/ritonavir 100 mg darba kuljum mingħajr omeprazole 20 mg darba kuljum.
English: Due to the similar pharmacodynamic effects and pharmacokinetic properties of omeprazole and esomeprazole, concomitant administration with esomeprazole and atazanavir is not recommended and concomitant administration with esomeprazole and nelfinavir is contraindicated (see section 4.3 and 4.4).
Maltese: Minħabba l-effetti farmakodinamiċi u l-karatteristiċi farmakokinetiċi simili ta' omeprazole u esomeprazole, l-għoti konkomitanti ma' esomeprazole u atazanavir mhuwiex rakkomandat u l-għoti konkomitanti ma' esomeprazole u nelfinavir huwa kontraindikat (ara sezzjonijiet 4.3 u 4.4).
English: Nexium Control 20 mg Tablets
Maltese: Nexium Control 20 mg Pilloli
English: Medicinal products which induce CYP2C19 and/or CYP3A4
Maltese: Prodotti mediċinali li jinduċu CYP2C19 u/jew CYP3A4
English: In two multicenter, randomized, double-blind, placebo-controlled pivotal studies 234 subjects with a recent history of frequent heartburn were treated with 20 mg esomeprazole for 4 weeks.
Maltese: F'żewġ studji pivitali, multiċentri, randomizzati, double-blind u kkontrollati bil-plaċebo, 234 individwu bi storja riċenti ta' ħruq ta' stonku frekwenti kienu kkurati b'20 mg esomeprazole għal 4 ġimgħat.
English: In a study in healthy subjects, there was a decreased exposure by almost 40% of the active metabolite of clopidogrel when a fixed dose combination of esomeprazole 20 mg + acetylsalicylic acid 81 mg was given with clopidogrel compared to clopidogrel alone.
Maltese: Fi studju fuq individwi b'saħħithom, kien hemm tnaqqis ta' madwar 40% fl-espożizzjoni talmetabolit attiv ta' clopidogrel meta kombinazzjoni ta' doża fissa ta' esomeprazole 20 mg + aċidu aċetilsaliċiliku (acetylsalicylic acid) 81 mg ingħatat ma' clopidogrel meta mqabbla ma' clopidogrel waħdu.
English: Musculoskeletal and connective tissue disorders arthralgia, myalgia muscular weakness
Maltese: Disturbi muskoluskeletriċi u tattessuti konnettivi artralġja, mijalġja dgħjufija muskolari
English: Thus, when esomeprazole is combined with medicinal products metabolised by CYP2C19, such as warfarin, phenytoin, citalopram, imipramine, clomipramine, diazepam, etc., the plasma concentrations of these medicinal products may be increased and a dose reduction could be needed.
Maltese: Għalhekk, meta esomeprazole jiġi kkombinat ma' prodotti mediċinali metabolizzati b'CYP2C19, bħal warfarin, phenytoin, citalopram, imipramine, clomipramine, diazepam, eċċ., ilkonċentrazzjonijiet ta' dawn il-prodotti mediċinali fil-plasma jistgħu jiżdiedu u jista' jkun hemm bżonn ta' tnaqqis fid-doża.
English: • Phenytoin (used to treat epilepsy).
Maltese: • Phenytoin (użat għall-kura tal-epilessija).
English: The proportion of patients maintaining an intragastric pH above 4 for at least 8, 12 and 16 hours respectively were for esomeprazole 20 mg 76%, 54%, and 24%.
Maltese: Il-proporzjonijiet ta' pazjenti li żammew pH intragastriku ogħla minn 4 għal mill-anqas 8, 12 u 16-il siegħa għal esomeprazole 20 mg kienu 76%, 54% u 24% rispettivament.
English: Esomeprazole is a CYP2C19 inhibitor.
Maltese: Esomeprazole huwa inibitur ta' CYP2C19.
English: To avoid this interference, Nexium Control treatment should be stopped for at least 5 days before CgA measurements (see section 5.1).
Maltese: Biex din l-interferenza tiġi evitata, il-kura bi Nexium Control għandha titwaqqaf għal mill-inqas 5 ijiem qabel il-kejl ta' CgA (ara sezzjoni 5.1).
English: For saquinavir (with concomitant ritonavir), increased serum levels (80-100%) have been reported during concomitant omeprazole treatment (40 mg once a day).
Maltese: Għal saquinavir (b'ritonavir konkomitanti), ġiet irrapportata żieda fil-livelli fis-serum (80-100%) matul kura konkomitanti b'omeprazole (40 mg darba kuljum).
English: Treatment with proton pump inhibitors (PPIs) may lead to a slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter and in hospitalised patients, also possibly Clostridium difficile (see section 5.1).
Maltese: Kura b'inibituri tal-pompa tal-proton (PPIs) tista' twassal għal żieda żgħira fir-riskju ta' infezzjonijiet gastrointestinali bħal Salmonella u Campylobacter u f'pazjenti li qegħdin jirċievu kura l-isptar, possibbilment anke Clostridium difficile (ara sezzjoni 5.1).
English: Concomitant treatment with omeprazole (20 mg daily) and digoxin in healthy subjects increased the bioavailability of digoxin by 10% (up to 30% in two out of ten subjects).
Maltese: Kura konkomitanti b'omeprazole (20 mg kuljum) u digoxin f'individwi b'saħħithom żiedet ilbijodisponibilità ta' digoxin b'10% (sa 30% fi tnejn minn għaxar individwi).
English: Immune system disorders hypersensitivity reactions e.g. fever, angioedema and anaphylactic reaction/shock
Maltese: Disturbi fissistema immuni reazzjonijiet ta' sensittività eċċessiva eż. deni, anġjoedema u reazzjoni anafilattika/xokk
English: • Phenytoin (used to treat epilepsy)
Maltese: • Phenytoin (użat għall-kura tal-epilessija)
English: Pfizer ApS, Consumer Healthcare (Danmark/Danmörk/Tanska) Tlf: +45 4420 1100
Maltese: Pfizer ApS, Consumer Healthcare (Danmark/Danmörk/Tanska)
English: Pack sizes of 7 and 14 gastro-resistant tablets.
Maltese: Daqs tal-pakketti ta' 7 u 14-il pillola gastro-reżistenti.
English: The majority of these rated the importance of this change to be Important to Extremely Important in performing their activities of daily living (79 - 86% at week 2).
Maltese: Il-maġġoranza tagħhom ikklassifikaw l-importanza ta' din ilbidla bħala Importanti sa Importanti Ħafna biex iwettqu l-attivitajiet tagħhom tal-ħajja ta' kuljum (79 - 86% f'ġimgħa 2).
English: • Dry mouth.
Maltese: Sess tal-persuna
English: • Disturbed sleep (insomnia), feeling sleepy.
Maltese: • Disturb fl-irqad (insomnja), sensazzjoni ta' ngħas.
English: This time and dose-dependency is due to a decrease of first pass metabolism and systemic clearance probably caused by an inhibition of the CYP2C19 enzyme by esomeprazole and/or its sulphone metabolite.
Maltese: Din id-dipendenza fuq il-ħin u d-doża hija minħabba tnaqqis fil-metaboliżmu tal-ewwel passaġġ u fittneħħija sistemika probabbilment ikkawżati minn inibizzjoni tal-enzima CYP2C19 minn esomeprazole u/jew il-metabolit sulphone tiegħu.
English: Ear and labyrinth disorders vertigo
Maltese: Disturbi fil-widnejn u fis-sistema labirintika vertiġini
English: • Citalopram, imipramine or clomipramine (used to treat depression).
Maltese: • Citalopram, imipramine jew clomipramine (użati għall-kura tad-depressjoni).
English: In healthy volunteers, concomitant administration of 40 mg esomeprazole resulted in a 32% increase in area under the plasma concentration-time curve (AUC) and a 31% prolongation of elimination half-life(t1/2) but no significant increase in peak plasma levels of cisapride.
Maltese: F'voluntiera b'saħħithom, l-għoti konkomitanti ta' 40 mg ta' esomeprazole wassal għal żieda ta' 32% fl-erja taħt il-kurva tal- konċentrazzjoni mal-ħin fil-plasma (AUC) u titwil ta' 31% tal-half-life(t1/2) tal eliminazzjoni imma l-ebda żieda sinifikanti fil-livelli massimi ta' cisapride fil-plasma.
English: What Nexium Control looks like and contents of the pack Nexium Control 20 mg gastro-resistant tablets are light pink, oblong, biconvex, 14 mm x 7 mm, filmcoated, engraved with ‘20 mG' on one side and A/EH on the other side.
Maltese: Nexium Control 20 mg pilloli gastro-reżistenti huma roża ċari, tawwalin, bikonvessi, ta' 14 mm x 7 mm, miksija b'rita, imnaqqxin b'‘20 mG' fuq naħa waħda u A/EH fuq in-naħa l-oħra.
English: Excipient(s) with known effect Each gastro-resistant hard capsule contains 11.5 mg sucrose.
Maltese: Kull kapsula iebsa gastro-reżistenti fiha 11.5 mg ta' sukrosju.
English: Omeprazole, given in doses of 40 mg to healthy subjects in a cross-over study, increased Cmax and AUC for cilostazol by 18% and 26% respectively, and one of its active metabolites by 29% and 69% respectively.
Maltese: Omeprazole, meta ngħata f'dożi ta' 40 mg lil individwi b'saħħithom fi studju cross-over, żied is-Cmax u l-AUC għal cilostazol bi 18% u 26% rispettivament, u wieħed mill-metaboliti tiegħu b'29% u 69% rispettivament.
English: • Citalopram, imipramine or clomipramine (used to treat depression)
Maltese: • Citalopram, imipramine jew clomipramine (użati għall-kura tad-depressjoni)
English: The remaining part is dependent on another specific isoform, CYP3A4, responsible for the formation of esomeprazole sulphone, the main metabolite in plasma.
Maltese: Il-parti li tifdal tiddependi fuq isoforma speċifika oħra, CYP3A4, li hija responsabbli għall-formazzjoni ta' esomeprazole sulphone, il-metabolit prinċipali fil-plażma.
English: • You are due to have a specific blood test (Chromogranin A).
Maltese: • Tkun ser tagħmel test tad-demm speċifiku (Chromogranin A).
English: The parameters below reflect mainly the pharmacokinetics in individuals with a functional CYP2C19 enzyme, extensive metabolisers.
Maltese: Il-parametri ta' hawn taħt jirriflettu prinċipalment il-farmakokinetika f'individwi b'enzima CYP2C19 funzjonali, jiġifieri metabolizzaturi estensivi.
English: • Digoxin (used for heart problems).
Maltese: • Digoxin (użat għall-problemi fil-qalb).
English: Adverse reactions not observed in clinical studies, but seen in animals at exposure levels similar to clinical exposure levels and with possible relevance to clinical use were as follows:
Maltese: Ir-reazzjonijiet avversi li ma kinux osservati fl-istudji kliniċi, iżda li dehru f'annimali f'livelli ta' espożizzjoni simili għal-livelli tal-espożizzjoni klinika u b'rilevanza possibbli għall-użu kliniku kienu kif ġej:
English: Subacute cutaneous lupus erythematosu s (see section
Maltese: lupus erythematosus tal-ġilda subakut (ara sezzjoni 4.4).
English: In both studies esomeprazole 20 mg was significantly better compared to placebo for the primary endpoint, complete resolution of heartburn, defined as no heartburn episodes during the last 7 days prior to the final visit (33.9% - 41.6% vs. placebo 11.9 - 13.7%, (p<0.001).
Maltese: Fiż-żewġ studji, esomeprazole 20 mg kien konsiderevolment aħjar meta mqabbel mal-plaċebo għallendpoint primarju, il-fejqan sħiħ tal-ħruq ta' stonku, definit bħala ebda episodju ta' ħruq ta' stonku matul l-aħħar 7 t'ijiem qabel l-aħħar vista (33.9% - 41.6% vs. plaċebo 11.9 - 13.7%, (p<0.001).
English: Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product.
Maltese: Pazjenti bi problemi ereditarji rari ta' intolleranza għal fruttosju, malassorbiment ta' glucose-galactose jew insuffiċjenza ta' sucraseisomaltase ma għandhomx jieħdu din il-mediċina.
English: Concomitant administration of esomeprazole and a CYP3A4 inhibitor, clarithromycin (500 mg twice a day (b.i.d.
Maltese: L-għoti konkomitanti ta' esomeprazole u inibitur ta' CYP3A4, clarithromycin (500 mg darbtejn kuljum (b.i.d.)), wassal għal irduppjar talespożizzjoni (AUC) għal esomeprazole.
English: A light pink, oblong, biconvex, film-coated, gastro-resistant tablet of 14 mm x 7 mm engraved with ‘20 mG' on one side and ‘A/EH' on the other side.
Maltese: Pillola gastro-reżistenti, roża ċara, tawwalija, ġejja għat-tond miż-żewġ naħat, miksija b'rita ta' 14 mm x 7 mm mnaqqxa b'‘20 mG' fuq naħa waħda u b'‘A/EH' fuq in-naħa l-oħra.
English: Other medicines and Nexium Control
Maltese: Mediċini oħra u Nexium Control
English: It belongs to a group of medicines called ‘proton pump inhibitors'.
Maltese: Huwa jappartjeni għal grupp ta' mediċini msejħa ‘inibituri tal-pompa tal-proton'.
English: Elderly patients (≥65 years old) The metabolism of esomeprazole is not significantly changed in elderly patients (71-80 years of age).
Maltese: Anzjani (≥65 sena) Il-metaboliżmu ta' esomeprazole ma jinbidilx b'mod sinifikanti f'pazjenti anzjani (71-80 sena).
English: Reproductive system and breast disorders gynaecomastia
Maltese: Disturbi fissistema riproduttiva u fissider ġinekomastja
English: • You have ever had a skin reaction after treatment with a medicine similar to Nexium Control that reduces stomach acid.
Maltese: • jekk qatt kellek reazzjoni fil-ġilda wara kura b'mediċina simili għal Nexium Control li tnaqqas l-aċtu fl-istonku.
English: Nervous system disorders headache dizziness, paraesthesia, somnolence taste disturbance
Maltese: Disturbi fissistema nervuża uġigħ ta' ras sturdament, parasteżija, ngħas disturb fittogħma
English: The pharmacokinetics of esomeprazole has been studied in doses up to 40 mg b.i.d.
Maltese: Il-farmakokinetika ta' esomeprazole ġiet studjata f'dożi sa 40 mg darbtejn kuljum.
English: Studies evaluating concomitant administration of esomeprazole and either naproxen or rofecoxib did not identify any clinically relevant pharmacokinetic interactions during short-term studies.
Maltese: Studji li evalwaw l-għoti konkomitanti ta' esomeprazole u jew naproxen jew rofecoxib ma identifikaw l-ebda interazzjoni farmakokinetikaklinikament rilevanti matul studji fuq perjodu qasir.
English: Hypersensitivity to the active substance, substituted benzimidazoles or to any of the excipients listed in section 6.1.
Maltese: Sensittività eċċessiva għas-sustanza attiva, sostituti ta' benzimidazoles jew għal kwalunkwe sustanza mhux attiva elenkata fis-sezzjoni 6.1.
English: • Digoxin (used for heart problems)
Maltese: • Digoxin (użat għall-problemi fil-qalb)
English: Approximately 2.9±1.5% of the population lack a functional CYP2C19 enzyme and are called poor metabolisers.
Maltese: Madwar 2.9±1.5% tal-popolazzjoni m'għandhomx enzima CYP2C19 funzjonali u jissejħu metabolizzaturi ħżiena.
English: For short-term treatment of reflux symptoms (heartburn, acid regurgitation) in adults, aged 18 or over.
Maltese: Għal kura għal żmien qasir ta' sintomi ta' rifluss (ħruq ta' stonku, rigurġitazzjoni ta' aċidu) fl-adulti, ta' 18-il sena u aktar.
English: • Generally feeling unwell and lacking energy.
Maltese: • Sensazzjoni ġenerali li ma tiflaħx u nuqqas ta' enerġija.
English: After five days of oral dosing with 20 mg and 40 mg of esomeprazole, intragastric pH above 4 was maintained for a mean time of 13 hours and 17 hours, respectively over 24 hours in symptomatic gastroesophageal reflux disease (GERD) patients.
Maltese: Wara ħamest ijiem ta' dożaġġ orali b'20 mg u 40 mg ta' esomeprazole, pH intragastriku ogħla minn 4 inżamm għal ħin medju ta' 13-il siegħa u 17-il siegħa, rispettivament fuq 24 siegħa f'pazjenti b'mard ta' rifluss gastroesofagali (GERD) sintomatiku.
English: • Erlotinib (used to treat cancer).
Maltese: • Erlotinib (użat għall-kura tal-kanċer).
English: Pharmacotherapeutic group: Drugs for acid related disorders, proton pump inhibitors, ATC code: A02BC05.
Maltese: Mediċini għal disturbi relatati mal-aċidu, inibituri tal-pompa talproton, Kodiċi ATC:
English: Nexium Control is available in a pack size of 14 gastro-resistant hard capsules in high-density polyethylene (HDPE) bottles with an induction seal closure and child resistant closure.
Maltese: Nexium Control huwa disponibbli f'daqs ta' pakkett ta' 14-il kapsula iebsa gastro-reżistenti fi fliexken tal-polietilene ta' densità għolja (high-density polyethylene HPDE) b'għeluq ta' siġill ta' induzzjoni u b'għeluq reżistenti għat-tfal.
English: The plasma elimination half-life is about 1.3 hours after repeated once-daily dosing.
Maltese: Il-half-life tal-eliminazzjoni mill-plażma hija madwar 1.3 sigħat wara għoti ripetut darba kuljum.
English: Alternatively, the tablet can be dispersed in half a glass of non-carbonated water.
Maltese: Inkella, il-pillola tista' tinħall f'nofs tazza ilma mhux karbonizzat.
English: This could be ‘Stevens-Johnson syndrome' or ‘toxic epidermal necrolysis', seen very rarely.
Maltese: Stevens-Johnson' jew ‘nekrolisi epidermika tossika', li dehru b'mod rari ħafna.
English: Nexium Control is indicated for the short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults.
Maltese: Nexium Control huwa indikat għall-kura għal żmien qasir ta' sintomi ta' rifluss (eż. ħruq ta' stonku u rigurġitazzjoni tal-aċidu) fl-adulti.
English: The investigators also found esomeprazole to be significantly more effective than placebo in resolving acid regurgitation (58.5% - 63.6% vs. placebo 28.3% - 37.4%) during the week 2 evaluation.
Maltese: L-investigaturi sabu wkoll li esomeprazole kien ferm iktar effettiv minn plaċebo fis-solliev ta' li wieħed itella' l-aċidu mill-istonku (58.5% - 63.6% vs. plaċebo 28.3%37.
English: Co-administration of omeprazole (40 mg once a day) reduced mean nelfinavir AUC, Cmax, and Cmin by 36 - 39 % and mean AUC, Cmax, and Cmin for the pharmacologically active metabolite M8 was reduced by 75 - 92%.
Maltese: L-għoti flimkien ta' omeprazole (40 mg darba kuljum) naqqas lAUC, is-Cmax u s-Cmin medji ta'nelfinavir b'36-39 % u l-AUC, is-Cmax u s-Cmin medji għall metabolit farmakoloġikament attiv M8 tnaqqas b'75-92%.
English: The symptoms described in connection with 280 mg esomeprazole were gastrointestinal symptoms and weakness.
Maltese: Is-sintomi deskritti b'rabta ma' 280 mg kienu sintomi gastrointestinali u dgħjufija.
English: It is important for you to give information about your medicine at this time.
Maltese: Importanti li tagħti informazzjoni dwar il-mediċina tiegħek f'dan il-waqt.
English: The investigators also found esomeprazole to be significantly more effective than placebo in resolving acid regurgitation (58.5% - 63.6% vs placebo 28.3% - 37.4%) during the week 2 evaluation.
Maltese: L-investigaturi sabu wkoll li esomeprazole kien ferm iktar effettiv minn plaċebo fis-solliev ta' li wieħed itella' l-aċidu mill-istonku (58.5% - 63.6% vs plaċebo 28.3%37.
English: • Feeling agitated, confused or depressed.
Maltese: • Tħossok aġitat/a, konfuż/a jew depress/a.
English: • Methotrexate (used to treat cancer and rheumatic disorders).
Maltese: • Methotrexate (użat biex jikkura l-kanċer u disturbi tar-rewmatiżmu).
English: • Erlotinib (used to treat cancer)
Maltese: • Erlotinib (użat għall-kura tal-kanċer)
English: You may take this medicine with antacids (e.g. magaldrate, alginic acid, sodium bicarbonate, aluminium hydroxide, magnesium carbonate or combinations of these) if needed.
Maltese: Tista' tieħu din il-mediċina ma' sustanzi kontra l-aċidi (eż. magaldrate, aċidu alġiniku, bikarbonat tassodju, idrossidu tal-aluminju, karbonat tal-manjeżju jew kombinazzjonijiet ta' dawn) jekk ikun meħtieġ.
English: Co-administration of omeprazole (40 mg once daily) with atazanavir 300 mg/ritonavir 100 mg to healthy volunteers resulted in a substantial reduction in atazanavir exposure (approximately 75% decrease in AUC, Cmax, and Cmin).
Maltese: L-għoti flimkien ta' omeprazole (40 mg darba kuljum) ma' atazanavir 300 mg/ritonavir 100 mg lil voluntiera b'saħħithom wassal għal tnaqqis sostanzjali fl-espożizzjoni għal atazanavir (tnaqqis ta' madwar 75% fl-AUC, s-Cmax, u s-Cmin).
English: • Joint pain (arthralgia) or muscle pain (myalgia).
Maltese: • Uġigħ fil-ġogi (artralġja) jew uġigħ fil-muskoli (majalġja).
English: Total plasma clearance is about 17 l/h after a single dose and about 9 l/h after repeated administration.
Maltese: It-tneħħija totali mill-plażma hija madwar 17 l/h wara doża waħda u madwar 9 l/h wara għoti ripetut.
English: Band
Maltese: Komuni
English: • Dizziness, tingling feelings such as “pins and needles”.
Maltese: • Sturdament, sensazzjonijiet ta' tingiż bħal “tnemnim”.
English: • Eyesight problems such as blurred vision.
Maltese: • Problemi fil-vista bħal vista mċajpra.
English: Following Overall Treatment Evaluation (OTE) of patients at week 2, 78.0-80.7% of patients on esomeprazole 20 mg, compared to 72.4 - 78.3% for placebo, reported their condition as improved.
Maltese: Wara Evalwazzjoni Globali tal-Kura (Overall Treatment Evaluation - OTE) tal-pazjenti fuq esomeprazole 20 mg, meta mqabbel ma' 72.4 - 78.3% għal plaċebo, irrappurtaw il-kundizzjoni tagħhom bħala li marret għall-aħjar.
English: After repeated once-daily administration of 40 mg esomeprazole, the mean area under the plasma concentration-time curve was approximately 100% higher in poor metabolisers than in subjects having a functional CYP2C19 enzyme (extensive metabolisers).
Maltese: Wara għoti ripetut darba kuljum ta' 40 mg esomeprazole, lerja medja taħt il-kurva tal-konċentrazzjoni fil-plażma mal-ħin kienet madwar 100% ogħla filmetabolizzaturi ħżiena milli f'individwi li kellhom enzima CYP2C19 funzjonali (metabolizzaturi estensivi).
English: • Methotrexate (used to treat cancer and rheumatic disorders)
Maltese: • Methotrexate (użat biex jikkura l-kanċer u disturbi tar-rewmatiżmu)
English: • Swallow your capsule whole with half a glass of water.
Maltese: • Ibla' l-kapsula sħiħa ma' nofs tazza ilma.
English: Pfizer Consumer Manufacturing Italy S.r.l.
Maltese: Pfizer Consumer Manufacturing Italy S.r.l. Via Nettunese, 90
English: After repeated administration with 20 mg esomeprazole once daily for five days, mean peak acid output after pentagastrin stimulation is decreased 90% when measured 6-7 hours after dosing on day five.
Maltese: Wara għoti ripetut ta' 20 mg esomeprazole darba kuljum għal ħamest ijiem, il-produzzjoni massima medja ta' aċidu wara stimulazzjoni tal-pentagastrin tonqos b'90% meta titkejjel 6-7 sigħat wara ddożaġġ fil-ħames jum.
English: What Nexium Control looks like and contents of the pack Nexium Control 20 mg gastro-resistant hard capsules are approximately 11 x 5 mm capsules with a clear body, and an amethyst cap imprinted with “NEXIUM 20 MG” in white.
Maltese: Nexium Control 20 mg kapsuli ibsin gastro-reżistenti huma kapsuli ta' madwar 11 x 5 mm b'korp ċar, u b'għatu ta' kulur amethyst b'kitba'“NEXIUM 20
English: Nexium Control contains sugar spheres, which contain sucrose, a type of sugar.
Maltese: Nexium Control fih sferi taz-zokkor, li fihom is-sucrose, tip ta' zokkor.
English: The secondary endpoint of complete resolution of heartburn, defined as no heartburn on the patient's diary card for 7 consecutive days, was statistically significant at both week 1 (10.0% - 15.2% vs placebo 0.9% - 2.4%, p = 0.014, p<0.001) and week 2 (25.2% - 35.7% vs placebo 3.4% - 9.0%, p<0.001).
Maltese: Ilpunt ta' tmiem sekondarju għall-fejqan komplet tal-ħruq tal-istonku, definit bħala ebda ħruq talistonku fuq il-kard tad-djarju tal-pazjent għal 7 t'ijiem konsekuttivi, kien statistikament sinifikanti kemm f'ġimgħa 1 (10.0% - 15.2% vs plaċebo 0.9% - 2.4%, p = 0.014, p<0.001) kif ukoll f'ġimgħa 2 (25.
English: Decreased gastric acidity due to any means including PPIs, increases gastric counts of bacteria normally present in the gastrointestinal tract.
Maltese: It-tnaqqis fl-aċidità gastrika minħabba kwalunkwe mezz fosthom il-PPIs, iżid l-għadd gastriku ta' batterji normalment preżenti fl-apparat gastro-intestinali.
English: • Swallow your tablet whole with half a glass of water.
Maltese: • Ibla' l-pillola sħiħa ma' nofs tazza ilma.
English: Increased gastric pH during omeprazole treatment may change the absorption of the protease inhibitors.
Maltese: Żieda fil-pH gastriku matul kura b'omeprazole tista' tbiddel l-assorbiment tal-inibituri tal-protease.
English: Esomeprazole is extensively plasma protein bound and is therefore not readily dialysable.
Maltese: Esomeprazole jintrabat b'mod estensiv mal-proteini fil-plasma u għalhekk ma jiġix dijalizzat malajr.
English: Aluminium blister.
Maltese: Folji tal-aluminju.