FrancophonIA/ELRC3.0 huggingface dataset:
English: Store in the original lead shielding.
Slovenian: Shranjujte v originalni svinčeni zaščiti.
English: Distribution Ioflupane (
Slovenian: Porazdelitev Joflupan (
English: Vial - 5 mL presentation
Slovenian: Viala - pakiranje po 5 ml
English: 6.6 Special precautions for disposal and other handling
Slovenian: D.P Posebni varnostni ukrepi za odstranjevanje in ravnanje z zdravilom
English: How Striascan is used
Slovenian: Kako uporabljati zdravilo Striascan
English: Respiratory, thoracic and mediastinal disorders
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora dispneja neznana pogostnost
English: Urinary bladder wall Uterus
Slovenian: Stena žolčnika
English: Renal impairment / Hepatic impairment
Slovenian: Okvara ledvic/jeter
English: If you are pregnant, do not use Striascan.
Slovenian: Če ste noseči, ne uporabljajte zdravila Striascan, saj bi vaš otrok lahko prejel nekaj radioaktivnosti.
English: Name and address of the manufacturer(s) responsible for batch release CIS BIO International
Slovenian: Ime in naslov izdelovalca (izdelovalcev), odgovornega (odgovornih) za sproščanje serij
English: Vial - 2.5 mL presentation
Slovenian: Viala - pakiranje po 2,5 ml
English: At the chemical concentrations used for diagnostic examinations, Striascan does not appear to have any pharmacodynamic activity.
Slovenian: Ne kaže, da ima zdravilo Striascan farmakodinamično delovanje pri kemičnih koncentracijah, ki se uporabljajo za diagnostične preglede.
English: Careful consideration of the benefit risk ratio in these patients is required since an increased radiation exposure is possible.
Slovenian: Pri teh bolnikih je možna večja izpostavljenost sevanju, zato je treba razmerje med tveganji in koristmi skrbno proučiti.
English: Each 5 mL single dose vial contains 370 MBq ioflupane (
Slovenian: Ena 5-mililitrska enoodmerna viala vsebuje 370 MBq joflupana (
English: Dizziness, formication (paraesthesia), dysgeusia
Slovenian: Bolezni živčevja glavobol pogosti omotica, mravljinčavost (parestezija), disgevzija občasni
English: Dyspnea
Slovenian: Dojki
English: 370 MBq / vial DD/MM/YYYY xx h xx CET 74 MBq / mL DD/MM/YYYY xx h xx CET
Slovenian: 370 MBq/vialo DD/MM/LLLL xx.
English: ioflupane (
Slovenian: joflupan (
English: 185 MBq / vial DD/MM/YYYY xx h xx CET 74 MBq / mL DD/MM/YYYY xx h xx CET
Slovenian: 185 MBq/vialo DD/MM/LLLL xx.
English: Immune system disorders
Slovenian: Bolezni imunskega sistema preobčutljivost neznana pogostnost
English: Radioactive medicine.
Slovenian: Radioaktivno zdravilo Znak za radioaktivnost
English: Uncommon (1/1,000 to <1/100) Rare
Slovenian: (1/1,000 do <1/100)
English: Any ioflupane (
Slovenian: Pri joflupanu (
English: F-91192 Gif-sur-Yvette Cedex FRANCE
Slovenian: 91192 Gif-sur-Yvette Cedex FRANCIJA
English: The values for the sensitivity of ioflupane (
Slovenian: Senzitivnost joflupana (
English: Bone surfaces Brain
Slovenian: Nadledvični žlezi Površina kosti
English: Nervous system disorders
Slovenian: Organski sistem po MedDRA Neželeni učinki
English: Oesophagus
Slovenian: Striascan.
English: Headache
Slovenian: Priželjc
English: Testes
Slovenian: Prebavila
English: How Striascan is stored
Slovenian: Shranjevanje zdravila Striascan
English: Ear and labyrinth disorders Vertigo
Slovenian: Ušesne bolezni, vključno z motnjami labirinta vrtoglavica občasni
English: Nausea, dry mouth
Slovenian: Bolezni prebavil navzea, suha usta občasni bruhanje neznana pogostnost
English: This is normal practice with medicines like Striascan.
Slovenian: Kaj vsebuje zdravilo Striascan
English: Contact your nuclear medicine doctor if you have any questions.
Slovenian: Če imate dodatna vprašanja, se posvetujte z zdravnikom nuklearne medicine.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Zometa on 20 March 2001.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Zometa, veljavno po vsej Evropski uniji, izdala 20. marca 2011.
English: What measures are being taken to ensure the safe and effective use of Zometa?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Zometa?
English: The full EPAR for Zometa can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Zometa je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: The usual dose of Zometa is one infusion of 4 mg over at least 15 minutes.
Slovenian: Običajni odmerek zdravila Zometa je ena 4-miligramska infuzija v trajanju najmanj 15 minut.
English: What benefit has Zometa shown during the studies?
Slovenian: Kakšne koristi je zdravilo Zometa izkazalo med študijami?
English: This is a summary of the European public assessment report (EPAR) for Zometa.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Zometa.
English: For more information about treatment with Zometa, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Zometa preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: Other information about Zometa
Slovenian: Druge informacije o zdravilu Zometa
English: The main measure of effectiveness was the number of patients whose calcium levels had returned to normal within 10 days after treatment.
Slovenian: Glavno merilo učinkovitosti je bilo število bolnikov, pri katerih se je raven kalcija v 10 dneh po zdravljenju vrnila na normalno raven.
English: What is the risk associated with Zometa?
Slovenian: Kakšna tveganja so povezana z zdravilom Zometa?
English: It is available as a powder (4mg) and solvent, and as a concentrate (4mg/5ml), both of which are made up into a solution for infusion (drip into a vein), and as a pre-prepared solution for infusion (4mg/100ml).
Slovenian: Na voljo je v obliki praška (4 mg) in vehikla ter koncentrata (4 mg/5 ml), ki se oba uporabita za pripravo raztopine za infundiranje (kapalne infuzije v veno), in kot predhodno pripravljene raztopine za infundiranje (4mg/100 ml).
English: A risk management plan has been developed to ensure that Zometa is used as safely as possible.
Slovenian: Za zagotovitev čim varnejše uporabe zdravila Zometa je bil pripravljen načrt obvladovanja tveganj.
English: Osteonecrosis of the jaw (damage to the bones of the jaw, which could lead to pain, sores in the mouth or loosening of teeth) has been reported uncommonly (seen in between 1 and 10 patients in 1,000).
Slovenian: O osteonekrozi čeljustnice (poškodbi čeljustnice, ki lahko povzroči bolečine, oteklost v ustih ali majanje zob) so poročali občasno (opaženo pri 1 do 10 bolnikih od 1 000).
English: The CHMP decided that Zometa's benefits are greater than its risks and recommended that it be given marketing authorisation.
Slovenian: CHMP je zaključil, da so koristi zdravila Zometa večje od z njim povezanih tveganj, in priporočil, da se zanj izda dovoljenje za promet.
English: In the third study, Zometa was as effective as pamidronate: 44% of the patients receiving Zometa had at least one skeletal event, compared with 46% of those receiving pamidronate.
Slovenian: V tretji študiji je bilo zdravilo Zometa enako učinkovito kot pamidronat: 44 % bolnikov, ki so prejemali zdravilo Zometa, je imelo vsaj en z okostjem povezan dogodek v primerjavi s 46 % tistih, ki so prejemali pamidronat.
English: The most common side effect with Zometa (seen in more than 1 patient in 10) is hypophosphataemia (low blood phosphate levels).
Slovenian: Najpogostejši neželeni učinek zdravila Zometa (opažen pri več kot 1 bolniku od 10) je hipofosfatemija (nizka raven fosfatov v krvi).
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Zometa, including the appropriate precautions to be followed by healthcare professionals and patients.
Slovenian: V skladu s tem načrtom so bile v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in bolniki.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Zometa.
Slovenian: Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil to zdravilo, na podlagi česar je oblikoval mnenje za izdajo dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
English: In addition, the company that markets Zometa will provide a card to inform patients about the risk of osteonecrosis of the jaw and to instruct them to contact their doctor if they experience symptoms.
Slovenian: Poleg tega bo družba, ki trži zdravilo Zometa, pripravila kartico, s katero bo bolnike seznanila s tveganjem pojava osteonekroze čeljustnice in jih pozvala, naj v primeru pojava simptomov poiščejo zdravniško pomoč.
English: Looking at the results of the two studies together, 88% of the patients receiving Zometa had normal calcium levels within 10 days after treatment, compared with 70% of those receiving pamidronate.
Slovenian: Na podlagi rezultatov obeh študij skupaj je mogoče ugotoviti, da je bila pri 88 % bolnikov, ki so prejemali zdravilo Zometa, raven kalcija v 10 dneh po zdravljenju normalna v primerjavi s 70 % tistih, ki so prejemali pamidronat.
English: In patients with hypercalcaemia, Zometa was more effective than pamidronate.
Slovenian: Pri bolnikih s hiperkalciemijo je bilo zdravilo Zometa učinkovitejše od pamidronata.
English: Zometa should not be used in pregnant or breastfeeding women.
Slovenian: Prav tako ga ne smejo uporabljati nosečnice in doječe ženske.
English: In the first two studies of patients with bone metastases, the number of patients who developed a new skeletal event was lower with Zometa (33 to 38%) than with placebo (44%).
Slovenian: V prvih dveh študijah pri bolnikih s kostnimi metastazami, ki so prejemali zdravilo Zometa, je bilo število bolnikov, pri katerih se je razvil nov, z okostjem povezan dogodek, manjše kot pri tistih, ki so prejemali placebo (od 33 do 38 % v primerjavi s 44 %).
English: Zoledronic acid
Slovenian: Zometa zoledronska kislina
English: The main measure of effectiveness was the number of patients who developed at least one new ‘skeletal event' over 13 months.
Slovenian: Glavno merilo učinkovitosti je bilo število bolnikov, pri katerih se je v 13 mesecih pojavil vsaj en nov z okostjem povezan dogodek.
English: Zometa must not be used in people who are hypersensitive (allergic) to zoledronic acid, other bisphosphonates or any of the other ingredients.
Slovenian: Zdravila Zometa ne smejo uporabljati osebe, ki so preobčutljive za (alergične na) zoledronsko kislino, druge difosfonate ali katero koli drugo sestavino zdravila.
English: Why has Zometa been approved?
Slovenian: Zakaj je bilo zdravilo Zometa odobreno?
English: Zometa has been studied in over 3,000 adults with bone metastases in three main studies looking at its ability to prevent bone damage.
Slovenian: Zdravilo Zometa so proučevali v treh glavnih študijah pri več kot 3 000 bolnikih s kostnimi metastazami, v katerih so raziskali njegovo sposobnost pri preprečevanju poškodb kosti.
English: When used to prevent bone complications, the infusion can be repeated every three to four weeks, and patients should also take supplements of calcium and vitamin D. A lower dose is recommended for patients with bone metastases (when cancer has spread to the bone) if they have mild to moderate problems with their kidneys.
Slovenian: Pri uporabi zdravila za preprečevanje z okostjem povezanih zapletov se infundiranje lahko ponovi vsake tri do štiri tedne, bolniki pa morajo prejemati tudi dodatek kalcija in vitamina D. Pri bolnikih s kostnimi metastazami (rakom, ki se je razširil na kosti), ki imajo blage do zmerne težave z ledvicami, je priporočljiv nižji odmerek zdravila.
English: This leads to less bone loss.
Slovenian: S tem se zmanjša izguba kostnega mase.
English: Zometa is a medicine that contains the active substance zoledronic acid.
Slovenian: Zometa je zdravilo, ki vsebuje zdravilno učinkovino zoledronska kislina.
English: For the full list of all side effects reported with Zometa, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Zometa, glejte navodilo za uporabo.
English: Zometa must only be used by a doctor who has experience in the use of this type of medicine given into a vein.
Slovenian: Zdravilo Zometa smejo uporabljati le zdravniki z izkušnjami z uporabo te vrste zdravil za intravensko uporabo.
English: Zometa has also been compared with pamidronate in two main studies involving a total of 287 adults with hypercalcaemia caused by tumours.
Slovenian: Zdravilo Zometa so v dveh glavnih študijah, v kateri je bilo vključenih skupno 287 odraslih bolnikov s hiperkalciemijo, ki jo povzročijo tumorji, primerjali tudi s pamidronatom.
English: The reduction of bone loss helps to make bones less likely to break, which is useful in preventing fractures in cancer patients with bone metastases.
Slovenian: Zmanjševanje izgubljanja kostne mase vpliva na manjšo lomljivost kosti, kar je koristno pri preprečevanju zlomov pri bolnikih z rakom z metastazami v kosteh.
English: Zometa can be used to prevent bone complications in adults with advanced cancer that is affecting the bone.
Slovenian: Zdravilo Zometa se lahko uporablja za preprečevanje z okostjem povezanih zapletov pri odraslih z napredovalim rakom, ki prizadene kosti.
English: This included any bone complications needing treatment with radiotherapy or surgery, any fractures or any spinal compression.
Slovenian: Gre za kakršne koli kostne zaplete, pri katerih je potrebno zdravljenje z obsevanjem ali operacija, zlome ali pojav spinalne kompresije.
English: By preventing the breakdown of bones, Zometa also helps to reduce the amount of calcium released into the blood.
Slovenian: Zdravilo Zometa s preprečevanjem razgradnje kosti pripomore tudi k znižanju ravni kalcija, ki se sprosti v kri.
English: Zometa was compared with placebo (a dummy treatment) in two of the studies, and with pamidronate (another bisphosphonate) in the third.
Slovenian: V dveh študijah so ga primerjali s placebom (zdravilom brez zdravilne učinkovine), v tretji pa s pamidronatom (drugim difosfonatom).
English: What is Zometa used for?
Slovenian: Za kaj se zdravilo Zometa uporablja?
English: How has Zometa been studied?
Slovenian: Kako je bilo zdravilo Zometa raziskano?
English: How does Zometa work?
Slovenian: Kako zdravilo Zometa deluje?
English: How is Zometa used?
Slovenian: Kako se zdravilo Zometa uporablja?
English: Appropriate monitoring is advised.
Slovenian: Priporočljivo je ustrezno spremljanje.
English: No new safety findings were observed.
Slovenian: Novih izsledkov o varnosti ni bilo.
English: Î Don't drive or operate machinery unless you're feeling well.
Slovenian: Î Ne vozite ali upravljajte strojev, če se ne počutite dobro.
English: If you are pregnant or could be pregnant, tell your doctor.
Slovenian: Če ste noseči ali bi lahko bili noseči, o tem obvestite svojega zdravnika.
English: • if you have type 1 diabetes - this needs different treatment.
Slovenian: • če imate sladkorno bolezen tipa 1 - potrebno je drugačno zdravljenje
English: The minimum effective oral dose is approximately 0.6 mg.
Slovenian: Najmanjši učinkoviti peroralni odmerek je približno 0,6 mg.
English: Protein binding was greater than 99.5%.
Slovenian: Vezava na beljakovine je bila več kot 99,5 %.
English: The clinical relevance of this observation has not been fully elucidated.
Slovenian: Klinični pomen tega opažanja ni povsem pojasnjen.
English: It is not known whether breast-feeding will lead to exposure of the infant to medicinal product.
Slovenian: Ni znano, ali dojenje povzroči izpostavljenost otroka temu zdravilu.
English: Rarely hypoglycaemic reactions can occur immediately and may be severe and not always easy to correct.
Slovenian: Redko se lahko nemudoma pojavijo hipoglikemične reakcije, ki so lahko hude in jih ni vedno lahko
English: There was no significant difference in the effect regardless of whether the drug was taken 30 minutes before or immediately before a meal.
Slovenian: Učinek zdravila se ni pomembno razlikoval, če je bilo uporabljeno 30 minut pred obrokom ali tik pred njim.
English: AVAGLIM should be taken once daily shortly before or during a meal (usually the first main meal of the day).
Slovenian: AVAGLIM je treba vzeti enkrat na dan, tik pred obrokom ali med njim (ponavadi pred ali med prvim dnevnim obrokom).
English: If a dose is forgotten, the following dose must not be increased.
Slovenian: Če bolnik pozabi vzeti odmerek, naslednjega odmerka ne sme povečati.
English: anabolic steroids and male sex hormones,
Slovenian: anabolni steroidi in moški spolni hormoni,
English: Packs of 14, 28, 56, 84 or 112 tablets.
Slovenian: Pakiranja s 14, 28, 56, 84 ali 112 tabletami.
English: These small changes are not clinically significant and, therefore, it is not necessary to administer rosiglitazone at any particular time in relation to meals.
Slovenian: Ti majhni spremembi nista klinično pomembni, zato rosiglitazona ni treba uporabljati v kakšnem posebnem časovnem presledku glede na obroke.
English: Your blood sugar levels may become too high or too low (see ‘Low blood sugar' in Section 4).
Slovenian: Vrednosti vašega krvnega sladkorja lahko postanejo previsoke ali prenizke (glejte "Nizek krvni sladkor« v poglavju 4).
English: Similar effects have been seen with other thiazolidinediones.
Slovenian: Podobne učinke so opažali z drugimi tiazolidindioni.
English: 3.6 (1.8) mg 1995.5 (682.6) mg *Similar relative effective doses (i.e approximately half maximal dose) for other sulphonylureas
Slovenian: 3,6 (1,8) mg 1995,5 (682,6) mg *Podobni relativno učinkoviti odmerki (tj. približno pol največjega odmerka) za druge sulfonilsečnine
English: If this applies to you, use appropriate contraception to avoid the possibility of an unplanned pregnancy (see ‘Pregnancy and
Slovenian: Če se to nanaša na vas, morate za preprečitev neželene nosečnosti uporabljati ustrezno obliko kontracepcije (glejte ‘Nosečnost in dojenje'
English: The inter-subject variability was large, with a 7-fold difference in unbound AUC between patients.
Slovenian: Interindividualna variabilnost je bila velika in razlika nevezane AUC je bila med bolniki 7-kratna.
English: The terminal half-life for radioactivity was about 130 h indicating that elimination of metabolites is very slow.
Slovenian: Terminalni razpolovni čas radioaktivnosti je okrog 130 ur, kar kaže, da je izločanje presnovkov zelo počasno.
English: You may be at risk of having low blood sugar and need hospital treatment.
Slovenian: Lahko se vam vrednost krvnega sladkorja zniža tako, da potrebujete bolnišnično zdravljenje.
English: Î Checking your blood sugar levels regularly is especially important if you are taking any of these medicines, even if you are feeling well
Slovenian: Î Redno preverjanje vrednosti vašega krvnega sladkorja je potrebno, še posebej karad jemljete katero od teh zdravil, čeprav se počutite dobro
English: However, this raises no safety concern regarding target or special populations as hepatic impairment is contraindicated and the phase III clinical studies included a considerable number of elderly patients and patients with mild to
Slovenian: Vendar to ne pomeni nobenih varnostnih zadržkov glede ciljnih ali posebnih populacij, ker okvara jeter pomeni kontraindikacijo, klinične študije III. faze pa so vključile veliko starejših bolnikov in bolnikov z blago do zmerno okvaro ledvic.
English: If you stop taking Avaglim, your blood sugar will not be controlled, and you may become unwell.
Slovenian: Če prenehate jemati zdravilo Avanglim, krvni sladkor ne bo več nadzorovan, vaše zdravstveno stanje pa se lahko poslabša.
English: Avaglim tablets contain a small amount of lactose.
Slovenian: Avaglim tablete vsebujejo majhno količino laktoze.
English: In the event of an overdose, it is recommended that appropriate supportive treatment should be initiated as dictated by the patient's clinical status.
Slovenian: V primeru prevelikega odmerjanja je priporočljivo uvesti ustrezno podporno terapijo, kot jo zahteva bolnikovo klinično stanje.
English: Don't take extra tablets to make up for a missed dose.
Slovenian: Ne jemljite dodatnih tablet, da bi tako nadomestili pozabljeni odmerek.
English: Some of the medicines most likely to do this are:
Slovenian: Zdravila, ki to lahko povzročijo so:
English: Avaglim can also strengthen or weaken the effects of medicines to prevent blood clots (anticoagulants such as warfarin).
Slovenian: Avaglim lahko okrepi ali zmanjša učinke zdravil za preprečevanje tvorbe krvnih strdkov (antikoagulantov, kot je varfarin).
English: Glimepiride AUC0-t, AUC0-inf and Cmax were increased by 30%, 19% and 55% respectively, on average.
Slovenian: AUC0-t, AUC0-inf oz. Cmax glimepirida so se v povprečju povečale za 30 %, 19 % oz. 55 %.
English: For rosiglitazone, Cmax values were decreased by approximately 32% with food.
Slovenian: Vrednosti Cmax rosiglitazona so se s hrano zmanjšale za približno 32 %.
English: Î Tell a doctor or pharmacist if you think that Avaglim is not working as it should, particularly if you are taking any other medicines.
Slovenian: Î Obvestite svojega zdravnika ali farmacevta, če menite, da zdravilo Avaglim ne deluje, kot bi moralo, še posebej, če jemljete katerokoli druga zdravila.
English: However, rosiglitazone promoted differentiation and reversal of mutagenic changes in human colon cancer cells in vitro.
Slovenian: Je pa rosiglitazon spodbudil diferenciacijo in preobrat mutagenih sprememb v celicah človeškega raka na kolonu in vitro.
English: However, the concomitant use of the active substances in patients in clinical studies and in widespread clinical use has not resulted in any unexpected interactions.
Slovenian: Vendar sočasna uporaba učinkovin v kliničnih študijah in med široko klinično uporabo ni povzročila nepričakovanih medsebojnih delovanj.
English: − Within 60 days of an important (pharmacovigilance or risk minimisation) milestone being reached
Slovenian: − v 60 dneh po pomembnem mejniku (farmakovigilančnem ali povezanem z zmanjševanjem
English: If ALT levels remain >3X the upper limit of normal, therapy should be discontinued.
Slovenian: Če raven ALT ostaja > 3-kratno zgornjo normalno mejo, je treba zdravljenje prekiniti.
English: Overdose of sulphonylureas, including glimepiride, can result in severe life-threatening hypoglycaemia lasting 12 to 72 hours, which may recur after apparent recovery.
Slovenian: Preveliko odmerjanje sulfonilsečnin, vključno z glimepiridom, lahko povzroči hudo, smrtno nevarno hipoglikemijo, ki traja od 12 do 72 ur in se lahko po navideznem okrevanju ponovi.
English: 10 Hepatitis may progress to liver failure.
Slovenian: 10 Hepatitis lahko napreduje v odpoved jeter.
English: The possible contribution of fluid retention to weight gain should be individually assessed as rapid and excessive weight gain has been reported very rarely as a sign of fluid retention.
Slovenian: Možni prispevek zastajanja tekočine k povečanju telesne mase je treba oceniti posamezno, saj so o hitrem in čezmernem povečanju telesne mase kot znaku zastajanja tekočine poročali zelo redko.
English: Î Tell your doctor as soon as possible if you get any of these symptoms - either for the first time or
Slovenian: Î Čimprej obvestite svojega zdravnika, če se pojavi katerikoli od teh simptomov - bodisi prvič ali
English: As with other sulphonylureas, this effect is based on an improvement in responsiveness of pancreatic beta cells to the physiological glucose stimulus.
Slovenian: Tako kot pri drugih sulfonilsečninah ta učinek temelji na izboljšani odzivnosti pankreatičnih celic beta na fiziološki glukozni stimulus.