FrancophonIA/ELRC3.0 huggingface dataset:
English: However, the limitations of these data and the uncertainties regarding extrapolation of ex vivo data to the clinical situation imply that no firm conclusions can be made for regular ibuprofen use, and no clinically relevant effect is considered to be likely for occasional ibuprofen use.
Slovenian: Toda zaradi nezadostnih podatkov in zaradi negotovosti glede ekstrapolacije podatkov ex vivo na klinično uporabo ni mogoče sprejeti nobenih trdnih sklepov, ki bi se nanašali na redno uporabo ibuprofena, klinično pomemben učinek v primeru občasne uporabe ibuprofena pa ni verjeten.
English: Rash, pruritus, skin bleeding (purpura)
Slovenian: Izpuščaj, srbenje, kožne krvavitve (purpura)
English: Each film-coated tablet contains 102.6 mg of lactose (as lactose monohydrate).
Slovenian: Ena filmsko obložena tableta vsebuje 102,6 mg laktoze (v obliki laktoze monohidrata).
English: 10 film-coated tablets 14 film-coated tablets 28 film-coated tablets 30 film-coated tablets 50 film-coated tablets 90 film-coated tablets 100 film-coated tablets
Slovenian: 10 filmsko obloženih tablet 14 filmsko obloženih tablet 28 filmsko obloženih tablet 30 filmsko obloženih tablet 50 filmsko obloženih tablet 90 filmsko obloženih tablet 100 filmsko obloženih tablet
English: Co-administration of heparin had no effect on the inhibition of platelet aggregation induced by clopidogrel.
Slovenian: Sočasna uporaba heparina ni imela nobenega učinka na zaviranje agregacije trombocitov, sprožene s klopidogrelom.
English: However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 2 ‘Warnings and precautions').
Slovenian: Vendar pa se morate nemudoma posvetovati s svojim zdravnikom, če ste glede krvavitve kakorkoli zaskrbljeni (glejte poglavje 2 »Opozorila in previdnostni ukrepi«).
English: Pharmacogenetics: In patients who are poor CYP2C19 metabolisers, clopidogrel at recommended doses forms less of the active metabolite of clopidogrel and has a smaller effect on platelet function.
Slovenian: Farmakogenetika: Pri bolnikih, ki so slabi presnavljalci s CYP2C19, med uporabo priporočenih odmerkov klopidogrela nastane manj aktivnega presnovka klopidogrela in ima manjši učinek na delovanje trombocitov.
English: If you forget to take Clopidogrel/Acetylsalicylic acid Teva If you forget to take a dose of Clopidogrel/Acetylsalicylic acid Teva, but remember within 12 hours of your usual time, take your tablet straight away and then take your next tablet at the usual time.
Slovenian: Če ste pozabili vzeti zdravilo Klopidogrel/acetilsalicilna kislina Teva Če ste pozabili vzeti odmerek zdravila Klopidogrel/acetilsalicilna kislina Teva in ste se nanj spomnili v 12 urah od običajnega časa jemanja, vzemite tableto takoj.
English: • hallucinations
Slovenian: • halucinacije,
English: • carbamazepine, or oxcarbazepine, medicines to treat some forms of epilepsy,
Slovenian: • karbamazepin ali okskarbazepin, zdravili za zdravljenje nekaterih oblik epilepsije,
English: Clopidogrel/Acetylsalicylic acid Teva is indicated for the prevention of atherothrombotic events in adult patients already taking both clopidogrel and acetylsalicylic acid (ASA).
Slovenian: Zdravilo Klopidogrel/acetilsalicilna kislina Teva je indicirano za preprečevanje aterotrombotičnih dogodkov pri odraslih bolnikih, ki že jemljejo tako klopidogrel kot acetilsalicilno kislino (ASA).
English: • methotrexate, a medicine used to treat severe joint disease (rheumatoid arthritis) or skin disease
Slovenian: • metotreksat, zdravilo za zdravljenje hude bolezni sklepov (revmatoidnega artritisa) ali bolezni kože (luskavice),
English: In a small number of cases, bleeding in the eye, inside the head, the lung or the joints has also been reported.
Slovenian: Poročali so o majhnem številu primerov krvavitev v očesu, glavi, pljučih ali sklepih.
English: If you become pregnant while taking Clopidogrel/Acetylsalicylic acid Teva, consult your doctor immediately as it is recommended not to take Clopidogrel/Acetylsalicylic acid Teva while you are pregnant.
Slovenian: Če med zdravljenjem z zdravilom Klopidogrel/acetilsalicilna kislina Teva zanosite, se nemudoma posvetujte s svojim zdravnikom, saj jemanje zdravila Klopidogrel/acetilsalicilna kislina Teva med nosečnostjo ni priporočljivo.
English: More than 30,000 patients entered into clinical trials with clopidogrel plus ASA at maintenance doses lower than or equal to 325 mg, and received a variety of concomitant medicinal products including diuretics, beta blockers, ACE Inhibitors, calcium antagonists, cholesterol lowering agents, coronary vasodilators, antidiabetic agents (including insulin), antiepileptic agents and GPIIb/IIIa antagonists without evidence of clinically significant adverse interactions.
Slovenian: Več kot 30.000 bolnikov je bilo vključenih v klinična preskušanja kombinacije klopidogrela in ASA v vzdrževalnih odmerkih, manjših ali enakih 325 mg ter med tem prejemali različna zdravila, med drugim diuretike, zaviralce adrenergičnih receptorjev beta, zaviralce ACE, kalcijeve antagoniste, zdravila za zniževanje holesterola, koronarne vazodilatatorje, antidiabetike (vključno z inzulinom), antiepileptike in antagoniste GPIIb/IIIa, brez dokaza o pojavu klinično pomembnih neželenih interakcij.
English: Each film-coated tablet contains 117.8 mg of lactose (as lactose monohydrate).
Slovenian: Ena filmsko obložena tableta vsebuje 117,8 mg laktoze (v obliki laktoze monohidrata).
English: No clinical data on exposure to the combination of clopidogrel/acetylsalicylic acid during pregnancy are available.
Slovenian: Kliničnih podatkov o izpostavljenosti kombinaciji klopidogrela/acetilsalicilne kisline v nosečnosti ni na voljo.
English: Following absorption, the ASA in the combination of clopidogrel/acetylsalicylic acid is hydrolyzed to salicylic acid with peak plasma levels of salicylic acid occurring within 1 hour of dosing, such that plasma levels of ASA are essentially undetectable 1.5-3 hours after dosing.
Slovenian: Po absorpciji se ASA iz kombinacije klopidogrela/acetilsalicilne kisline hidrolizira v salicilno kislino, ki doseže največjo koncentracijo v plazmi v 1 uri po odmerjanju, tako da je koncentracija ASA v plazmi po 1,5 do 3 urah po odmerjanju praktično nezaznavna.
English: Aluminium + Dessicant - Aluminium blisters.
Slovenian: Aluminij + sušilno sredstvo - aluminijasti pretisni omoti.
English: The clinically relevant adverse reactions observed in four major studies, the CAPRIE study (a study comparing clopidogrel alone to ASA) and the CURE, CLARITY and COMMIT studies (studies comparing clopidogrel plus ASA to ASA alone) are discussed below.
Slovenian: Spodaj so prikazani klinično pomembni neželeni učinki, ki so jih opazili v štirih študijah: študiji CAPRIE (je primerjala klopidogrel sam z ASA) in študijah CURE, CLARITY in COMMIT (so primerjale kombinacijo klopidogrela in ASA s samo ASA).
English: Do not use this medicine after the expiry date which is stated on the carton, bottle and blister after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli, plastenki in pretisnem omotu poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
English: • ASA or another non-steroidal anti-inflammatory medicine usually used to treat painful and/or inflammatory conditions of muscle or joints,
Slovenian: • ASA ali kakšno drugo nesteroidno protivnetno zdravilo, ki jih običajno uporabljamo za zdravljenje bolečin in/ali vnetja mišic ali sklepov,
English: As no clinical data on exposure to clopidogrel during pregnancy are available, it is preferable not to use clopidogrel during pregnancy as a precautionary measure.
Slovenian: Ker kliničnih podatkov o izpostavljenosti klopidogrelu med nosečnostjo ni, je potrebna previdnost, zato se uporabo klopidogrela med nosečnostjo odsvetuje.
English: Mean peak plasma levels of unchanged clopidogrel (approximately 2.2-2.5 ng/ml after a single 75 mg oral dose) occurred approximately 45 minutes after dosing.
Slovenian: Povprečna največja koncentracija nespremenjenega klopidogrela v plazmi (približno 2,2-2,5 ng/ml po enem 75 mg peroralnem odmerku) se je pojavila približno 45 minut po odmerjanju.
English: Esomeprazole is expected to give a similar interaction with clopidogrel.
Slovenian: Pričakovati je, da je medsebojno delovanje esomeprazola in klopidogrela podobno.
English: ASA: The following symptoms are associated with moderate intoxication: dizziness, headache, tinnitus, confusion and gastrointestinal symptoms (nausea, vomiting and gastric pain).
Slovenian: ASA: Zmerna zastrupitev, povezana s sledečimi simptomi: omotico, glavobolom, tinitusom, zmedenostjo in prebavnimi simptomi (navzea, bruhanje in bolečina v želodcu).
English: • Active pathological bleeding such as peptic ulcer or intracranial haemorrhage.
Slovenian: • hude jetrne okvare, • aktivne patološke krvavitve, kot je peptična razjeda ali intrakranialna krvavitev.
English: If you forget for more than 12 hours, simply take the next single dose at the usual time.
Slovenian: Če ste tableto pozabili vzeti pred več kot 12 urami, preprosto vzemite naslednjo tableto ob običajnem času.
English: Recent transient ischaemic attack or stroke
Slovenian: Nedavna tranzitorna ishemična ataka ali možganska kap
English: If any of the situations mentioned below apply to you, you should tell your doctor before taking Clopidogrel/Acetylsalicylic acid Teva:
Slovenian: Če karkoli od spodaj naštetega velja za vas, morate o tem obvestiti svojega zdravnika, preden vzamete zdravilo Klopidogrel/acetilsalicilna kislina Teva:
English: Pack sizes of 14, 28 and 30 film-coated tablets.
Slovenian: Velikosti pakiranj po 14, 28 in 30 filmsko obloženih tablet.
English: • gout (a condition of painful, swollen joints caused by uric acid crystals)
Slovenian: • protin (boleči, otekli sklepi, kar povzročijo kristali sečne kisline)
English: • oral anticoagulants, medicines used to reduce blood clotting,
Slovenian: • peroralne antikoagulanse, zdravila proti strjevanju krvi,
English: • if you have had a clot in an artery of your brain (ischaemic stroke) which occurred in the last
Slovenian: • če ste imeli strdek v možganski arteriji (ishemična kap), ki se je pojavil v zadnjih sedmih dneh,
English: • Non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction) including patients undergoing a stent placement following percutaneous
Slovenian: • akutnem koronarnem sindromu brez elevacije ST spojnice (nestabilna angina ali miokardni infarkt brez Q zobca), vključno z bolniki, katerim je bila vstavljena opornica po perkutani
English: Tests are available to identify a patient's CYP2C19 genotype.
Slovenian: Na voljo so testi za ugotavljanje bolnikovega CYP2C19 genotipa.
English: Other concomitant therapy with ASA
Slovenian: Drugo sočasno zdravljenje z ASA
English: • If you have a medical condition that include the combination of asthma, nasal discharge (runny nose) and polyps (a type of growth in the nose).
Slovenian: • če imate obolenje, ki je kombinacija astme, izcedka iz nosu in polipov (vrsta tkivne rašče v nosu),
English: • sore mouth (stomatitis)
Slovenian: • vnetje v ustih (stomatitis),
English: Due to the risk of bleeding and haematological adverse reactions, blood cell count determination and/or other appropriate testing should be promptly considered whenever clinical symptoms suggestive of bleeding arise during the course of treatment (see section 4.8).
Slovenian: Zaradi tveganja za krvavitve in hematološke neželene učinke je potrebno v primeru kliničnih simptomov, ki nakazujejo krvavitev med zdravljenjem, takoj pregledati krvno sliko in/ali opraviti druge ustrezne preiskave (glejte poglavje 4.8).
English: As a precaution, concomitant use of strong or moderate CYP2C19 inhibitors should be discouraged (see section 4.5 for a list of CYP2C19 inhibitors, see also section 5.2).
Slovenian: Iz previdnosti je sočasna uporaba močnih ali srednje močnih zaviralcev CYP2C19 odsvetovana (za seznam zaviralcev CYP2C19 glejte poglavje 4.5; glejte tudi poglavje 5.2).
English: It is characterised by thrombocytopenia and microangiopathic haemolytic anaemia associated with either neurological findings, renal dysfunction or fever.
Slovenian: Zanjo je značilna trombocitopenija in mikroangiopatična hemolitična anemija povezana bodisi z nevrološkimi spremembami, motnjami v delovanju ledvic ali povečano telesno temperaturo.
English: Respiratory tract bleeding (haemoptysis, pulmonary haemorrhage), bronchospasm, interstitial pneumonitis, non-cardiogenic pulmonary edema with chronic use and in the context of a hypersensitivity reaction due to acetylsalicylic acid*, eosinophilic pneumonia.
Slovenian: Krvavitve v dihalih (hemoptiza, pljučna krvavitev), bronhospazem, intersticijski pnevmonitis, nekardiogeni pljučni edem zaradi kronične uporabe in v zvezi s preobčutljivostno reakcijo zaradi acetilsalicilne kisline*, eozinofilna pljučnica
English: Experimental data suggest that ibuprofen may inhibit the effect of low dose aspirin on platelet aggregation when they are dosed concomitantly.
Slovenian: Eksperimentalni podatki kažejo, da lahko ibuprofen med sočasno uporabo majhnih odmerkov aspirina zavre njen učinek na agregacijo trombocitov.
English: Patients should be evaluated for history of hypersensitivity to another thienopyridine (such as clopidogrel, ticlopidine, prasugrel) since cross-reactivity among thienopyridines has been reported (see section 4.8).
Slovenian: Pri bolnikih je treba preveriti, če so bile v preteklosti prisotne preobčutljivostne reakcije na druge tienopiridine (kot npr. klopidogrel, tiklopidin, prasugrel), saj so poročali o navzkrižni reaktivnosti med tienopiridini (glejte poglavje 4.8).
English: The recommended dose is one tablet of Clopidogrel/Acetylsalicylic acid Teva per day, to be taken orally with a glass of water, with or without food.
Slovenian: Priporočeni odmerek je ena tableta zdravila Klopidogrel/acetilsalicilna kislina Teva na dan, ki jo vzamete s kozarcem vode.
English: Tests are available to determine a patient's CYP2C19 genotype.
Slovenian: Na voljo so testi, ki omogočajo določitev bolnikovega genotipa CYP2C19.
English: • omeprazole, esomeprazole or cimetidine, medicines to treat upset stomach,
Slovenian: • omeprazol, esomeprazol ali cimetidin, zdravila za zdravljenje težav z želodcem,
English: The combination of clopidogrel/acetylsalicylic acid should be used with caution in patients with a history of peptic ulcer or gastroduodenal haemorrhage or minor upper GI symptoms as this may be due to gastric ulceration which may lead to gastric bleeding.
Slovenian: Kombinacijo klopidogrela/acetilsalicilne kisline morate previdno uporabljati pri bolnikih s peptično razjedo, gastroduodenalnimi krvavitvami ali manj izrazitimi gastrointestinalnimi simptomi zgornjega trakta v anamnezi, saj so ti simptomi lahko posledica želodčne razjede, ki lahko povzroči krvavitev v želodcu.
English: The number of patients experiencing the primary endpoint [cardiovascular (CV) death, myocardial infarction (MI), or stroke] was 582 (9.3%) in the clopidogrel plus ASA group and 719 (11.4%) in the ASA group, a 20% relative risk reduction (RRR) (95% CI of 10%-28%; p=0.00009) for the clopidogrel plus ASA group [17% relative risk reduction when patients were treated conservatively, 29% when they underwent percutaneous transluminal coronary angioplasty (PTCA) with or without stent and 10% when they underwent coronary artery bypass graft (CABG)].
Slovenian: Število bolnikov s primarnim opazovanim dogodkom [srčnožilna (SŽ) smrt, miokardni infarkt (MI) ali kap] je bilo 582 (9,3 %) v skupini, zdravljeni s klopidogrelom in z ASA ter 719 (11,4 %) v skupini, ki je prejemala ASA, kar je 20 % zmanjšanje relativnega tveganja (95 % IZ od 10 % do 28 %; p=0,00009) v skupini, zdravljeni s klopidogrelom in z ASA [17 % zmanjšanje relativnega tveganja, če so bili bolniki zdravljeni konzervativno, 29 % kadar je bila izvedena perkutana transluminalna koronarna angioplastika z ali brez stenta in 10 %, če je bila izvedena premostitvena operacija koronarnih arterij].
English: • Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) and syndrome of asthma, rhinitis, and nasal polyps.
Slovenian: • pri bolnikih, ki so preobčutljivi za nesteroidna protivnetna zdravila (NSAID) in bolnikih s sindromom astme, rinitisa in nosnih polipov.
English: • fluconazole, voriconazole, ciprofloxacin, or chloramphenicol, medicines to treat bacterial and fungal infections,
Slovenian: • flukonazol, vorikonazol, ciprofloksacin ali kloramfenikol, zdravila za zdravljenje bakterijskih in glivičnih okužb,
English: Consistent with the above results, in a meta analysis including 6 studies of 335 clopidogrel-treated subjects at steady state, it was shown that active metabolite exposure was decreased by 28% for intermediate metabolisers, and 72% for poor metabolisers while platelet aggregation inhibition (5 μM ADP) was decreased with differences in IPA of 5.9% and 21.4%, respectively, when compared to extensive metabolisers.
Slovenian: V skladu z zgornjimi rezultati so izsledki metaanalize, ki je zajela 6 študij, s 335 bolniki, zdravljenih s klopidogrelom, v stanju dinamičnega ravnovesja, pokazali, da se je v primerjavi z obsežnimi metabolizatorji izpostavljenost aktivnemu presnovku pri srednje dobrih metabolizatorjih zmanjšala za 28 %, pri slabih metabolizatorjih se je zmanjšala za 72 %, zavrtje agregacije trombocitov (5 µM ADP) pa se je zmanjšalo, in sicer z razliko pri IPA v višini 5,9 % oziroma 21,4 % v primerjavi z dobrimi metabolizatorji.
English: Rare side effect (may affect up to 1 in 1000 people): • vertigo.
Slovenian: Redki neželeni učinki (pojavijo se lahko pri največ 1 od 1.000 bolnikov): • vrtoglavica.
English: Do NOT take Clopidogrel/Acetylsalicylic acid Teva during third trimester of pregnancy.
Slovenian: Zdravila Klopidogrel/acetilsalicilna kislina Teva NE smete jemati v tretjem tromesečju nosečnosti.
English: As a dual antiplatelet agent, the combination of clopidogrel/acetylsalicylic acid should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery or other pathological conditions and in patients receiving treatment with other NSAIDs including Cox-2 inhibitors, heparin, glycoprotein IIb/IIIa inhibitors, selective serotonin reuptake inhibitors (SSRIs), or thrombolytics.
Slovenian: Kombinacijo klopidogrela/acetilsalicilne kisline, kot dvojno antiagregacijsko sredstvo, je treba previdno uporabljati pri bolnikih s povečanim tveganjem za krvavitev zaradi poškodbe, kirurškega posega ali drugih patoloških stanj ter pri bolnikih, ki so zdravijo z drugimi nesteroidnimi protivnetnimi zdravili, vključno z zaviralci Cox-2, heparinom, zaviralci glikoproteina IIb/IIIa, selektivnimi zaviralci ponovnega privzema serotonina ali trombolitiki.
English: Colitis (including ulcerative or lymphocytic colitis)
Slovenian: Kolitis (vključno z ulceroznim ali limfocitnim kolitisom).
English: If you are breast-feeding or planning to breast-feed, talk to your doctor before taking this medicine.
Slovenian: Če dojite ali načrtujete dojenje, se pred uporabo tega zdravila posvetujte s svojim zdravnikom.
English: Clopidogrel/Acetylsalicylic acid Teva contains clopidogrel and acetylsalicylic acid (ASA) and belongs to a group of medicines called antiplatelet medicinal products.
Slovenian: Zdravilo Klopidogrel/acetilsalicilna kislina Teva vsebuje klopidogrel in acetilsalicilno kislino (ASA) in spada v skupino zdravil, ki se imenujejo zaviralci agregacije trombocitov.
English: • excessive gas in stomach or intestines
Slovenian: • napihnjenost v želodcu ali črevesju,
English: Subsequently a respiratory acidosis occurs as a result of a suppressive effect on the respiratory centre.
Slovenian: Posledično se zaradi supresivnega učinka na dihalni center pojavi respiratorna acidoza.
English: Acetylsalicylic acid inhibits platelet aggregation by irreversible inhibition of prostaglandin cyclo-oxygenase and thus inhibits the generation of thromboxane A2, an inducer of platelet aggregation and vasoconstriction.
Slovenian: Acetilsalicilna kislina zavira agregacijo trombocitov z ireverzibilnim zavrtjem prostaglandinske ciklooksigenaze in s tem zavira nastajanje tromboksana A2, ki inducira agregacijo trombocitov in vazokonstrikcijo.
English: Moreover, the safety profile of clopidogrel in this subgroup of patients did not raise any particular concern.
Slovenian: Poleg tega, pri tej podskupini bolnikov niso ugotovili nobenih posebnih težav z varnostjo klopidogrela.
English: The combination of clopidogrel/acetylsalicylic acid has no or negligible influence on the ability to drive and use machines.
Slovenian: 4.7 Vpliv na sposobnost vožnje in upravljanja s stroji Kombinacija klopidogrela/acetilsalicilna kisline ne vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja s stroji.
English: As a precaution concomitant use of strong or moderate CYP2C19 inhibitors should be discouraged (see sections 4.4 and 5.2).
Slovenian: Iz previdnosti, se sočasno uporabo močnih ali srednje močnih zaviralcev CYP2C19 odsvetuje (glejte poglavji 4.4 in 5.2).
English: What you need to know before you take Clopidogrel/Acetylsalicylic acid Teva
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Klopidogrel/acetilsalicilna kislina Teva
English: You should not breast-feed while using this medicine.
Slovenian: Tega zdravila ne smete jemati med obdobjem dojenja.
English: The marketing authorisation holder shall submit PSURs for this product in accordance with the requirements set out in the list of Union reference dates (EURD list) provided for under Article
Slovenian: Imetnik dovoljenja za promet z zdravilom mora redno posodobljena poročila o varnosti zdravila za to zdravilo predložiti v skladu z zahtevami, določenimi v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES in objavljenem na evropskem spletnem portalu o zdravilih.
English: What Clopidogrel/Acetylsalicylic acid Teva is and what it is used for
Slovenian: Kaj je zdravilo Klopidogrel/acetilsalicilna kislina Teva in za kaj ga uporabljamo
English: Clopidogrel/Acetylsalicylic acid Teva is a fixed-dose combination medicinal product for continuation of therapy in:
Slovenian: Zdravilo Klopidogrel/acetilsalicilna kislina Teva je kombinirano zdravilo s stalnim odmerkom za nadaljevalno zdravljenje pri:
English: GI undesirable effects including stomach pain, heartburn, nausea, vomiting, and GI bleeding may occur.
Slovenian: Pojavijo se lahko gastrointestinalni neželeni učinki, vključno z bolečino v želodcu, zgago, navzeo, bruhanjem in krvavitvijo v prebavila.
English: Yellow, film-coated capsule shaped tablets.
Slovenian: filmsko obložena tableta (tableta) Rumene, filmsko obložene tablete v obliki kapsule.
English: How to store Clopidogrel/Acetylsalicylic acid Teva Contents of the pack and other information
Slovenian: Shranjevanje zdravila Klopidogrel/acetilsalicilna kislina Teva Vsebina pakiranja in dodatne informacije
English: - For more than 12 hours: patients should take the next dose at the regular scheduled time and should not double the dose.
Slovenian: - če je zamuda več kot 12 ur, naj bolnik naslednji odmerek vzame ob običajnem času in naj ne vzame dvojnega odmerka.
English: The most common side effect which has been seen with Clopidogrel/Acetylsalicylic acid Teva is bleeding.
Slovenian: Najpogostejši neželeni učinek med zdravljenjem z zdravilom Klopidogrel/acetilsalicilna kislina Teva so krvavitve.
English: Fifteen percent (15.0%) of patients in the clopidogrel plus ASA group and 21.7% in the group treated with ASA alone reached the primary endpoint, representing an absolute reduction of 6.7% and a 36% odds reduction in favor of clopidogrel (95% CI: 24, 47%; p <0.001), mainly related to a reduction in occluded infarct-related arteries.
Slovenian: Primarni opazovani dogodek je bil opažen pri 15,0 % bolnikov v skupini, ki je prejemala klopidogrel in ASA ter 21¸7 % bolnikov v skupini, ki je prejemala samo ASA, kar predstavlja absolutno zmanjšanje za 6,7 % in 36 % zmanjšanje verjetnosti v prid klopidogrela (95% IZ: 24%, 47 %; p<0,001) v glavnem zaradi zmanjšanja zaradi infarkta zamašenih arterij.