FrancophonIA/ELRC3.0 huggingface dataset:
English: The effect of antihypertensive veterinary medicinal products, especially angiotensin converting enzyme (ACE)-inhibitors, may be potentiated when co-administered with torasemide.
Slovenian: Učinek antihipertenzivnih zdravil, zlasti zaviralcev angiotenzinske konvertaze (ACE), je lahko pri sočasnem jemanju torasemida okrepljen.
English: Therefore, diuretic activity of torasemide correlates better with the rate of torasemide excretion in the urine than with the concentration in the blood.
Slovenian: Tako je diuretično delovanje torasemida bolj povezano s stopnjo izločanja torasemida v urin kot z njegovo koncentracijo v krvi.
English: The proportion of torasemide excreted in the urine is approximately the same in fasted or fed conditions (61% vs. 59% respectively).
Slovenian: Delež torasemida, ki se izloči z urinom, je pri teščih in sitih psih skoraj enak (61- oz. 59-odstoten).
English: Doses of 0.26 mg/kg and higher should only be administered for a maximum period of 5 days.
Slovenian: Odmerke 0,26 mg/kg ali več smemo dajati največ 5 dni.
English: In case of accidental ingestion, particularly by a child, seek medical advice immediately and show the package leaflet or the label to the physician.
Slovenian: V primeru nenamernega zaužitja, zlasti pri otroku, se takoj posvetujte z zdravnikom in mu pokažite navodila za uporabo ali ovojnino.
English: In dogs, following a single intravenous dose of 0.2 mg torasemide/kg bodyweight, the mean total clearance was 22.1 mL/h/kg, with a mean volume of distribution of 166 mL/kg and a mean terminal half-life of about 6 hours.
Slovenian: Pri psih je bil po enkratnem intravenskem odmerku 0,2 mg torasemida/kg telesne mase povprečni skupni očistek 22,1 ml/h/kg, povprečni volumen porazdelitve je bil 166 ml/kg, povprečni končni razpolovni čas pa je znašal 6 ur.
English: Do not use concomitantly with other loop diuretics.
Slovenian: Ne uporabite sočasno z drugimi diuretiki Henlejeve zanke.
English: > 8 to 11.5
Slovenian: > 8 do 11,5
English: Two metabolites (a dealkylated and a hydroxylated metabolite) have been identified in urine.
Slovenian: V urinu sta bila identificirana dva presnovka (dealkilirani in hidroksilirani presnovek).
English: The initial/maintenance dose may be temporarily increased when pulmonary oedema becomes more severe, i.e. reaching alveolar oedema state (see section "Dosage for each species, route(s) and method of administration").
Slovenian: Začetni/vzdrževalni odmerek se lahko začasno poveča, če postane stanje pljučnega edema resnejše, tj. če doseže stanje alveolarnega edema (glejte poglavje »Odmerki za posamezne živalske vrste ter pot(i) in način uporabe zdravila«).
English: Since protein binding facilitates the renal secretion of torasemide, a decrease in binding due to displacement by another drug may be a cause of diuretic resistance.
Slovenian: Ker vezava proteinov pospešuje ledvično izločanje torasemida, je lahko manjša vezava zaradi izpodrivanja z drugim zdravilom vzrok odpornosti na diuretike.
English: > 15 to 23
Slovenian: > 15 do 23
English: The following clinical signs were observed commonly: episodic gastrointestinal signs such as vomiting and diarrhoea, dehydration, polyuria, polydipsia, urinary incontinence, anorexia, weight loss and lethargy.
Slovenian: Pogosto so bili opaženi naslednje klinični znaki: epizode gastrointestinalnih motenj, kot sta bruhanje in driska, dehidracija, poliurija, polidipsija, urinska inkontinenca, anoreksija, izguba telesne mase in letargija.
English: Consequently water reabsorption from the collecting duct is inhibited and the volume of water on the luminal side is increased.
Slovenian: To zmanjšuje reabsorpcijo vode iz zbiralnega kanala in poveča količino vode na luminalni strani.
English: Lactose monohydrate Cellulose microcrystalline Povidone (K30) Pork liver powder flavour Compressible sugar Crospovidone (type B) Magnesium stearate
Slovenian: 6.1 Seznam pomožnih snovi laktoza monohidrat celuloza, mikrokristalna povidon (K30) aroma svinjskih jeter v prahu saharoza, kompresibilna krospovidon (tip B) magnezijev stearat
English: If symptoms of allergy occur, seek medical advice and show the product packaging to the physician.
Slovenian: Če se pojavijo simptomi alergije, se posvetujte z zdravnikom in mu pokažite navodila za uporabo ali ovojnino.
English: Remaining tablet parts should be stored in the blister and be given at the next administration.
Slovenian: Preostale dele tablete je treba shranjevati v pretisnem omotu in jih porabiti za naslednji odmerek.
English: (0.26 to 0.40 mg/kg/day)
Slovenian: Začasni visoki odmerek (0,26 do 0,40 mg/kg/dan)
English: Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Slovenian: Ne uporabite v primeru preobčutljivosti na učinkovino ali na katero koli pomožno snov.
English: Once signs of congestive heart failure have been controlled and the patient is stable, it should be continued at the lowest effective dose if long term diuretic therapy with this product is required.
Slovenian: Ko so znaki kongestivnega srčnega popuščanja nadzorovani in je pes stabilen, je v primeru potrebe po dolgotrajnem diuretičnem zdravljenju z zdravilom treba nadaljevati z najnižjim učinkovitim odmerkom.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE Cardboard box (30 tablets)
Slovenian: PODATKI NA ZUNANJI OVOJNINI Kartonska škatla (30 tablet)
English: In dogs with acute pulmonary oedema requiring emergency treatment, the use of injectable medicinal products should be considered first before commencing oral diuretic therapy.
Slovenian: Pri psih z akutnim pljučnim edemom, ki zahteva nujno zdravljenje, je treba pred začetkom peroralnega zdravljenja z diuretikom najprej razmisliti o uporabi zdravil za injiciranje.
English: Transferring treatment from an alternative loop diuretic to this veterinary medicinal product has not been evaluated and such a change should only be implemented based on a benefit-risk assessment performed by the responsible veterinarian.
Slovenian: Ker zamenjava alternativnega diuretika Henlejeve zanke z zdravilom za uporabo v veterinarski medicini ni bila ocenjena, naj do take zamenjave pride samo na podlagi ocene razmerja korist - tveganje odgovornega veterinarja.
English: Store out of reach of animals.
Slovenian: Hranite izven dosega živali.
English: THE WORDS “FOR ANIMAL TREATMENT ONLY”
Slovenian: BESEDILO »SAMO ZA ŽIVALI« Samo za živali.
English: > 11.5 to 15
Slovenian: > 11,5 do 15
English: No pharmacokinetic interactions have been reported following co-administration of torasemide with digoxin; however hypokalaemia can enhance digoxin-induced arrhythmias.
Slovenian: Po sočasni uporabi torasemida in digoksina niso poročali o farmakokinetičnih interakcijah, čeprav lahko hipokaliemija sproži srčne aritmije, povzročene z digoksinom.
English: The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)) - common (more than 1 but less than 10 animals in 100 animals treated) - uncommon (more than 1 but less than 10 animals in 1,000 animals treated) - rare (more than 1 but less than 10 animals in 10,000 animals treated) - very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
Slovenian: Pogostost neželenih učinkov je določena po naslednjem dogovoru: - zelo pogosti (neželeni učinki se pokažejo pri več kot 1 od 10 zdravljenih živali) - pogosti (pri več kot 1, toda manj kot 10 živali od 100 zdravljenih živali) - občasni (pri več kot 1, toda manj kot 10 živali od 1.000 zdravljenih živali) - redki (pri več kot 1, toda manj kot 10 živali od 10.000 zdravljenih živali) - zelo redki (pri manj kot 1 živali od 10.000 zdravljenih živali, vključno s posameznimi primeri)
English: The tablets are flavoured.
Slovenian: Tablete imajo dodan okus.
English: The recommended initial/maintenance dose is 0.13 to 0.25 mg torasemide/kg bodyweight/day, once daily.
Slovenian: Priporočeni začetni/vzdrževalni odmerek torasemida je 0,13 do 0,25 mg/kg enkrat dnevno.
English: Do not use in cases of renal failure.
Slovenian: Ne uporabite v primeru odpovedi ledvic.
English: This veterinary medicinal product may cause hypersensitivity (allergic) reactions in persons that are sensitized to torasemide.
Slovenian: Pri osebah, ki so preobčutljive na torasemid, lahko zdravilo povzroči preobčutljivostne (alergijske) reakcije.
English: The safety and efficacy of the product has not been assessed for dogs weighing less than 2.5 kg. For these animals use only according to the benefit/risk assessment by the responsible veterinarian.
Slovenian: Varnost in učinkovitost zdravila nista bili ocenjeni pri psih, lažjih od 2,5 kg.
English: Feeding significantly increased torasemide AUC0-∞ by 37% and slightly delayed Tmax, but in fasted and fed conditions the maximal concentrations (Cmax) are approximately the same (2015 µg/L vs 2221 µg/L, respectively).
Slovenian: Hranjenje je znatno povečalo AUC0-∞ torasemida za 37 % in rahlo upočasnilo Tmax, maksimalne koncentracije (Cmax) pri teščih in sitih psih pa so bile skoraj enake (2015 µg/l v primerjavi z 2221 µg/l).
English: > 23 to 30
Slovenian: > 23 do 30
English: > 30 to 40
Slovenian: > 30 do 40
English: Renal function (measurement of blood urea and creatinine as well as urine protein: creatinine (UPC) ratio), hydration status and serum electrolytes status should be monitored prior to and during treatment at very regular intervals according to the benefit-risk assessment performed by the responsible veterinarian (see sections 4.3 and 4.6 of the SPC).
Slovenian: Ledvično funkcijo (merjenje sečnine in kreatinina v krvi ter proteinov v urinu: razmerje med beljakovinami in kreatininom v urinu - UPC), stanje hidracije in stanje serumskih elektrolitov je treba pred in med zdravljenjem spremljati v zelo rednih časovnih intervalih v skladu z oceno razmerja korist - tveganje odgovornega veterinarja (glejte poglavji 4.3 in 4.6 Povzetka glavnih značilnosti zdravila - SPC).
English: In case of loss of appetite and/or vomiting and/or lethargy or in case of treatment adjustment, renal function (blood urea and creatinine as well as urine protein:creatinine (UPC) ratio) should be assessed.
Slovenian: Ob izgubi apetita in/ali bruhanju in/ali letargiji oziroma v primeru prilagoditve zdravljenja je treba preveriti ledvično delovanje (sečnino in kreatinin v krvi ter proteine v urinu: razmerje med beljakovinami in kreatininom v urinu - UPC).
English: Torasemide belongs to the pyridine-3-sulfonylurea class of loop diuretics, also called high-ceiling diuretics.
Slovenian: Torasemid je diuretik Henlejeve zanke iz skupine piridin-3-sulfonilsečnine, ki se imenujejo tudi diuretiki vhodnega kraka Henlejeve zanke.
English: Renal function (measurement of blood urea and creatinine as well as urine protein: creatinine (UPC) ratio), hydration status and serum electrolytes status should be monitored prior to and during treatment at very regular intervals according to the benefit-risk assessment performed by the responsible veterinarian (see sections "Contraindications" and "Adverse reactions").
Slovenian: Ledvično funkcijo (merjenje sečnine in kreatinina v krvi ter proteinov v urinu: razmerje med beljakovinami in kreatininom v urinu - UPC), stanje hidracije in stanje serumskih elektrolitov je treba pred in med zdravljenjem spremljati v zelo rednih časovnih intervalih v skladu z oceno razmerja korist - tveganje odgovornega veterinarja (glejte razdelka »Kontraindikacije« in »Neželeni učinki«).
English: Other effects consistent with the pharmacological activity of torasemide were observed in pre-clinical studies in healthy dogs at the recommended dose, i.e. dry mucosa of the oral cavity, reversible increases in glucose and aldosterone serum concentrations, decrease in urine specific gravity and increase in urine pH.
Slovenian: Drugi učinki, značilni za farmakološko delovanje torasemida, so bili ob priporočenem odmerku v predkliničnih študijah opaženi pri zdravih psih, npr. suha sluznica v ustni votlini, reverzibilno povečanje serumskih koncentracij glukoze in aldosterona, zmanjšanje specifične teže urina in zvišanje pH-vrednosti urina.
English: Co-administration of loop diuretics and NSAIDs can result in a decreased natriuretic response.
Slovenian: Sočasna uporaba diuretikov Henlejeve zanke in nesteroidnih protivnetnih zdravil (NSAID) lahko povzroči zmanjšan natriuretski odziv.
English: A. MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. STATEMENT OF THE MRLs
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE C. NAVEDBA NAJVIŠJIH DOVOLJENIH KOLIČIN OSTANKOV ZDRAVILA (MRL)
English: After administration to healthy dogs of 3 times and 5 times the maximum dose for 5 consecutive days followed by 177 daily administrations of 3 times and 5 times the highest therapeutic recommended dose for maintenance, histopathological changes in the kidneys (interstitial inflammation, dilatation of renal tubules and subscapular cysts) were noted in addition to the effects observed after the administration of the recommended dose (see section 4.6).
Slovenian: Pri zdravih psih, ki so pet zaporednih dni prejeli 3- in 5-kratni maksimalni odmerek, čemur je sledilo 177 dni jemanja 3- in 5-kratnega najvišjega priporočenega vzdrževalnega terapevtskega odmerka, so poleg učinkov, značilnih za odmerjanje v priporočenem odmerku, opazili histopatološke spremembe v ledvicah (intersticijsko vnetje, razširitev ledvičnih tubulov in subskapularne ciste) (glejte poglavje 4.6).
English: In a clinical field study, renal insufficiency, a transient increase in renal blood parameters, haemoconcentration and alterations in electrolyte levels (chloride, sodium, potassium, phosphorus, magnesium, calcium) were very commonly observed.
Slovenian: V terenski klinični študiji so bili zelo pogosto opaženi ledvična okvara, prehodno povečanje ledvičnih krvnih parametrov, hemokoncentracija in spremembe na elektrolitski ravni (klor, natrij, kalij, fosfor, magnezij, kalcij).
English: After administration to healthy dogs of 3 times and 5 times the maximum dose for 5 consecutive days followed by 177 daily administrations of 3 times and 5 times the highest therapeutic recommended dose for maintenance, histopathological changes in the kidneys (interstitial inflammation, dilatation of renal tubules and subscapular cysts) were noted in addition to the effects observed after the administration of the recommended dose (see section "Adverse reactions").
Slovenian: Pri zdravih psih, ki so pet zaporednih dni prejeli 3- in 5-kratni maksimalni odmerek, čemur je sledilo 177 dni jemanja 3- in 5-kratnega najvišjega priporočenega vzdrževalnega terapevtskega odmerka, so poleg učinkov, značilnih za odmerjanje v priporočenem odmerku, opazili histopatološke spremembe v ledvicah (intersticijsko vnetje, razširitev ledvičnih tubulov in subskapularne ciste) (glejte poglavje »Neželeni učinki«).
English: Pharmacotherapeutic group: Cardiovascular system, high-ceiling diuretics, plain sulfonamides ATC vet code: QC03CA04
Slovenian: Oznaka ATC vet: QC03CA04
English: In a clinical field study, renal insufficiency, an increase in renal blood parameters, haemoconcentration and alterations in electrolyte levels (chloride, sodium, potassium, phosphorus, magnesium, calcium) were very commonly observed.
Slovenian: V terenski klinični študiji so bili zelo pogosto opaženi ledvična okvara, povečanje ledvičnih krvnih parametrov, hemokoncentracija in spremembe na elektrolitski ravni (klor, natrij, kalij, fosfor, magnezij, kalcij).
English: In cases of co-administration with corticosteroids, the effects of loss of potassium may be potentiated.
Slovenian: V primeru sočasne uporabe s kortikosteroidi lahko pride do povečane izgube kalija.
English: Since the ascending limb of the loop of Henle is impermeable to water, the inhibition of Na and Cl movement from the lumen to the interstitial space increases the concentration of ions in the lumen and produces a hypertonic medullary interstitium.
Slovenian: +-Cl z lumna v intersticijski prostor poveča koncentracije ionov v lumnu in ustvari hipertonično medularno intersticijo.
English: - rare (more than 1 but less than 10 animals in 10,000 animals treated) - very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
Slovenian: - pogosti (pri več kot 1, toda manj kot 10 živali od 100 zdravljenih živali) - občasni (pri več kot 1, toda manj kot 10 živali od 1.000 zdravljenih živali) - redki (pri več kot 1, toda manj kot 10 živali od 10.000 zdravljenih živali) - zelo redki (pri manj kot 1 živali od 10.000 zdravljenih živali, vključno s posameznimi primeri)
English: Torasemide has a more potent, longer-acting diuretic activity than furosemide.
Slovenian: Diuretični učinek torasemida je močnejši in dolgotrajnejši od učinka furosemida.
English: After administration of 3 and 5 times the highest therapeutic recommended dose to healthy dogs, a decrease of appetite was observed which led to a weight loss in some cases.
Slovenian: Pri zdravih psih, ki so prejeli 3- do 5-kratnik najvišjega priporočenega terapevtskega odmerka, so opazili izgubo teka, ki je v nekaterih primerih pripeljala do zmanjšanja telesne mase.
English: The initial/maintenance dose may be temporarily increased when pulmonary oedema becomes more severe, i.e. reaching alveolar oedema state (see section 4.9).
Slovenian: 4.4 Posebna opozorila za vsako ciljno živalsko vrsto Začetni/vzdrževalni odmerek se lahko začasno poveča, če postane stanje pljučnega edema resnejše, tj. če doseže stanje alveolarnega edema (glejte poglavje 4.9).
English: Torasemide causes a significant, dose-dependent increase in urine flow and the urinary excretion of sodium and potassium.
Slovenian: Torasemid povzroči precej pogostejše odvajanje urina ter izločanje natrija in kalija z urinom, ki sta odvisna od odmerka.
English: Chewable tablet.
Slovenian: Žvečljive tablete.
English: No accumulation of torasemide is observed after repeated once daily oral administration for 10 days, whatever the dose administered (ranging from 0.1 to 0.4 mg/kg) even if a slight supra dose proportionality is observed.
Slovenian: Ne glede na velikost odmerka (v razponu od 0,1 do 0,4 mg/kg) pri večkratnem peroralnem odmerjanju enkrat dnevno v obdobju 10 dni niso opazili akumulacije torasemida kljub rahli sorazmernosti pri supraterapevtskih odmerkih.
English: The primary site of action of torasemide is the thick ascending limb of the loop of Henle, where it interacts with the Na +-K
Slovenian: Glavno mesto delovanja torasemida je medularni del ascendentnega dela Henlejeve zanke, kjer reagira s kotransporterjem Na
English: Each chewable tablet contains:
Slovenian: KAKOVOSTNA IN KOLIČINSKA SESTAVA Ena žvečljiva tableta vsebuje:
English: 30 chewable tablets 90 chewable tablets
Slovenian: 90 žvečljivih tablet
English: Monitoring of glycaemia in diabetic animals is recommended prior to and during treatment.
Slovenian: Pred začetkom zdravljenja in med zdravljenjem je priporočljivo spremljanje glikemije pri živalih s sladkorno boleznijo.
English: Transient dose response alterations in the adrenal glands, consisting of minimal to moderate reactive hypertrophy/hyperplasia, presumably related to high production of aldosterone, were observed in the dogs treated with up to 5 times the highest therapeutic recommended dose.
Slovenian: Pri psih, ki so jih zdravili z do 5-kratnim najvišjim priporočenim terapevtskim odmerkom, so prehodne spremembe odziva na odmerek zaznali v nadledvičnih žlezah v obliki minimalno do zmerno reaktivne hipertrofije/hiperplazije, domnevno povezane z veliko proizvodnjo aldosterona.
English: This veterinary medicinal product may cause increased urination, thirst and/or gastrointestinal disturbances and/or hypotension and/or dehydration if ingested.
Slovenian: Posebni previdnostni ukrepi, ki jih mora izvajati oseba, ki živalim daje zdravilo Zdravilo lahko ob zaužitju povzroči povečano uriniranje, žejo in/ali prebavne motnje in/ali hipotenzijo in/ali dehidracijo.
English: Furthermore, the diuretic effect of torasemide is approximately the same in fed and fasted conditions.
Slovenian: Diuretični učinek torasemida je pri sitih in teščih psih približno enak.
English: Torasemide may antagonise the action of oral hypoglycaemic agents.
Slovenian: Torasemid lahko zavira delovanje peroralnih antidiabetikov.
English: 1 mg of torasemide
Slovenian: 1 mg torasemida
English: Furthermore, the diuretic effect of torasemide is approximately the same in fed or fasted conditions.
Slovenian: Diuretični učinek torasemida je pri sitih ali teščih psih približno enak.
English: torasemide
Slovenian: KARENCA
English: Isemid 1 mg chewable tablets Isemid 2 mg chewable tablets Isemid 4 mg chewable tablets torasemide
Slovenian: Isemid 4 mg žvečljive tablete torasemid
English: 2 mg of torasemide
Slovenian: 2 mg torasemida
English: The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)) - common (more than 1 but less than 10 animals in 100 animals treated) - uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
Slovenian: Pogostost neželenih učinkov je določena po naslednjem dogovoru: - zelo pogosti (neželeni učinki se pokažejo pri več kot 1 od 10 zdravljenih živali)
English: Isemid 1 mg chewable tablets for dogs (2.5-11.5 kg) Isemid 2 mg chewable tablets for dogs (> 11.5-23 kg) Isemid 4 mg chewable tablets for dogs (> 23-60 kg) torasemide
Slovenian: Isemid 1 mg žvečljive tablete za pse (2,5-11,5 kg) Isemid 2 mg žvečljive tablete za pse (> 11,5-23 kg) Isemid 4 mg žvečljive tablete za pse (> 23-60 kg) torasemid
English: Number and strength of Isemid tablets to be administered Initial/Maintenance dose
Slovenian: Število in jakost odmerjenih tablet zdravila Isemid Začetni/vzdrževalni odmerek (0,13 do 0,25 mg/kg/dan)
English: PACKAGE LEAFLET Isemid 1 mg chewable tablets for dogs (2.5-11.5 kg) Isemid 2 mg chewable tablets for dogs (> 11.5-23 kg) Isemid 4 mg chewable tablets for dogs (> 23-60 kg)
Slovenian: NAVODILO ZA UPORABO Isemid 1 mg žvečljive tablete za pse (2,5-11,5 kg) Isemid 2 mg žvečljive tablete za pse (> 11,5-23 kg) Isemid 4 mg žvečljive tablete za pse (> 23-60 kg)
English: 4 mg of torasemide
Slovenian: 4 mg torasemida
English: Pack sizes of 30 or 90 tablets.
Slovenian: VELIKOST PAKIRANJA 30 žvečljivih tablet
English: Oblong brown scored tablets.
Slovenian: Podolgovate rjave tablete z razdelilno zarezo.
English: THE WORDS “KEEP OUT OF THE SIGHT AND REACH OF CHILDREN”
Slovenian: BESEDILO »ZDRAVILO SHRANJUJTE NEDOSEGLJIVO OTROKOM« Zdravilo shranjujte nedosegljivo otrokom.
English: Children and adolescents (< 18 years)
Slovenian: Otroci in mladostniki (< 18 let)
English: Usually you will not experience any symptoms when these changes occur.
Slovenian: Ponavadi ne boste imeli nikakršnih simptomov, kadar se pojavijo te spremembe.
English: Date of first authorisation: 07 September 2007 Date of latest renewal: 12 September 2012
Slovenian: Datum prve odobritve: 7. september 2007 Datum zadnjega podaljšanja: 12. september 2012
English: Follow-up time was 28 days.
Slovenian: Čas sledenja je bil 28 dni.
English: Not known (cannot be estimated from the available data).
Slovenian: Neznana (ni mogoče oceniti iz razpoložljivih podatkov)
English: • Pregnancy (see sections 4.6 and 5.3).
Slovenian: • Nosečnost (glejte poglavji 4.6 in 5.3).
English: Distribution and biotransformation
Slovenian: Porazdelitev in biotransformacija
English: In this case, this medicine should be used with caution because your blood pressure may be decreased.
Slovenian: V tem primeru je treba zdravilo uporabljati previdno, ker se vaš krvni tlak lahko zniža.
English: Side effects are divided into the following two categories:
Slovenian: Neželeni učinki so razdeljeni v naslednji dve kategoriji:
English: The pharmacist or nurse will calculate the exact dose you need and the amount of the solution (in ml) you have to drink.
Slovenian: Farmacevt ali medicinska sestra bosta izračunala natančni odmerek, ki ga potrebujete, in količino raztopine (v ml), ki jo morate spiti.
English: • If you have a heart disease or had heart disease in the past, you should tell your doctor.
Slovenian: • Če imate ali ste v preteklosti imeli srčno bolezen, morate povedati zdravniku.