FrancophonIA/ELRC3.0 huggingface dataset:
English: Fluconazole intravenous infusion is compatible with the following administration fluids: a) Dextrose 5% and 20% b) Ringer's solution c) Hartmann's solution d) Potassium chloride in dextrose e) Sodium bicarbonate 4.2% and 5% f) Aminosyn 3.5% g) Sodium chloride 9 mg/ml (0.9%) h) Dialaflex (interperitoneal dialysis Soln 6.36%)
Slovenian: Flukonazol intravenska infuzija je združljiva z naslednjimi raztopinami za dajanje: a) 5 % in 20 % dekstroza b) Ringerjeva raztopina c) Hartmannova raztopina d) Kalijev klorid v dekstrozi e) 4,2 % in 5 % natrijev bikarbonat f) 3,5 % aminozin g) Natrijev klorid 9 mg/ml (0,9 %) h) Dialaflex (6,36 % raztopina za interperitonealno dializo)
English: Such a hormone change has not been observed in women treated with fluconazole (see section 5.1).
Slovenian: Pri ženskah, zdravljenih s flukonazolom, takšnih hormonskih sprememb niso ugotovili (glejte poglavje 5.1).
English: Fluconazole is a triazole antifungal agent.
Slovenian: Flukonazol je triazolsko protiglivično sredstvo.
English: • Tinea unguinium (onychomycosis) when other agents are not considered appropriate.
Slovenian: • Tinea unguinium (onychomycosis) kadar druga zdravila ne veljajo za primerna.
English: What Diflucan looks like and contents of the pack
Slovenian: Izgled zdravila Diflucan in vsebina pakiranja
English: 150 mg every third day for a total of 3 doses (day 1, 4, and 7) followed by 150 mg once weekly maintenance dose
Slovenian: 150 mg vsak tretji dan do skupno treh odmerkov (1., 4. in 7. dan), čemur sledi vzdrževalni odmerek 150 mg enkrat na teden
English: A measuring cup is provided with the 175 ml bottle.
Slovenian: Pri 175 ml plastenki je dodana merilna skodelica.
English: Fluconazole did not affect the fertility of male or female rats treated orally with daily doses of 5, 10, or 20 mg/kg or with parenteral doses of 5, 25, or 75 mg/kg.
Slovenian: Flukonazol ni vplival na plodnost podganjih samcev ali samic, ki so dobivali dnevne odmerke 5, 10 ali 20 mg/kg peroralno oziroma 5, 25 ali 75 mg/kg parenteralno.
English: Term newborn infants (from 15 to 27 days)
Slovenian: Normalno donošeni novorojenčki (od 15 do 27 dni)
English: Fluconazole has the potential to increase the systemic exposure of the calcium channel antagonists.
Slovenian: Flukonazol lahko poveča sistemsko izpostavljenost zaviralcev kalcijevih kanalčkov.
English: In combination therapy, symptoms of rifabutin toxicity should be taken into consideration.
Slovenian: Pri kombiniranem zdravljenju je treba upoštevati znake zastrupitve z rifabutinom.
English: Once opened, Diflucan may be used for a maximum of 30 days.
Slovenian: Ko je bilo enkrat odprto, se lahko zdravilo Diflucan uporablja največ 30 dni.
English: You might be given this medicine by your doctor to treat genital thrush, infection of the vagina or penis.
Slovenian: To zdravilo vam je zdravnik morebiti predpisal za zdravljenje glivičnega obolenja spolovil, okužbe nožnice ali penisa.
English: - Invasive candidiasis - Cryptococcal meningitis
Slovenian: - Invazivna kandidoza - Kriptokokni meningitis
English: - The medicinal product does not require any special storage conditions.
Slovenian: - Za shranjevanje zdravila niso potrebna posebna navodila.
English: The discontinuation of fluconazole presumably caused an enhanced CYP3A4 activity which led to increased metabolism of prednisone.
Slovenian: Prenehanje zdravljenja s flukonazolom je domnevno povzročilo povečano aktivnost CYP3A4, to pa je privedlo do povečane presnove prednizona.
English: In animal studies, there is a correlation between MIC values and efficacy against experimental mycoses due to Candida spp.
Slovenian: Razmerje med farmakokinetiko in farmakodinamiko (PK/PD) V študijah na živalih obstaja soodvisnost med vrednostmi minimalnih inhibitornih koncentracij (MIK) in učinkovitostjo nasproti eksperimentalnim mikozam, povzročenim s Candida spp.
English: - Once opened, Diflucan may be used for a maximum of 30 days.
Slovenian: - Ko je bilo enkrat odprto, se lahko zdravilo Diflucan uporablja največ 30 dni.
English: • Cryptococcal meningitis (see section 4.4).
Slovenian: • Kriptokoknega meningitisa (glejte poglavje 4.4).
English: The evidence for efficacy of fluconazole in the treatment of other forms of endemic mycoses such as paracoccidioidomycosis, lymphocutaneous sporotrichosis and histoplasmosis is limited, which prevents specific dosing recommendations.
Slovenian: Dokazi o učinkovitosti flukonazola za zdravljenje ostalih oblik globoke endemične mikoze, kot so Parakokcidioidomikoza, Limfokutana sporotrihoza in Histoplazmoza, so omejeni, zato ni mogoče dati posebnih priporočil o odmerjanju.
English: Fluconazole is metabolised only to a minor extent.
Slovenian: Flukonazol se presnavlja le v majhnem obsegu.
English: Benzodiazepines (short acting), i.e. midazolam, triazolam: Following oral administration of midazolam, fluconazole resulted in substantial increases in midazolam concentrations and psychomotor effects.
Slovenian: Benzodiazepini (kratkotrajno delujoči, npr. midazolam, triazolam): Po peroralni uporabi midazolama je flukonazol povzročil bistveno povečanje koncentracije midazolama in njegovih psihomotoričnih učinkov.
English: The most frequently (>1/10) reported adverse reactions are headache, abdominal pain, diarrhoea, nausea, vomiting, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased and rash.
Slovenian: Neželeni učinki, o katerih so poročali najpogosteje (> 1/10), so glavobol, bolečine v trebuhu, driska, navzea, bruhanje, povečana raven alanin aminotransferaze, povečana raven aspartat aminotransferaze, povečana raven alkalne fosfataze v krvi in kožni izpuščaji.
English: Symptomatic treatment (with supportive measures and gastric lavage if necessary) may be adequate.
Slovenian: Utegnilo bi zadostovati simptomatsko zdravljenje (s podpornimi ukrepi in izpiranjem želodca, če je potrebno).
English: Keep the bottle tightly closed.
Slovenian: Plastenko shranjujte dobro zaprto.
English: HMG CoA reductase inhibitors: The risk of myopathy and rhabdomyolysis increases when fluconazole is coadministered with HMG-CoA reductase inhibitors metabolised through CYP3A4, such as atorvastatin and simvastatin, or through CYP2C9, such as fluvastatin.
Slovenian: Zaviralci reduktaze HMG-CoA: Nevarnost pojava miopatije in rabdomiolize se poveča, če flukonazol uporabimo sočasno z zaviralci reduktaze HMG-CoA, ki se presnavljajo s CYP3A4 (npr. atorvastatin ali simvastatin) ali s CYP2C9 (npr. fluvastatin).
English: probably due to an inhibition of the warfarin metabolism through CYP2C9.
Slovenian: verjetno zaradi zavrtja presnove varfarina prek CYP2C9.
English: After reconstitution, the volume of the suspension is 110 ml, providing a usable volume of 100 ml.
Slovenian: Po rekonstituciji volumen suspenzije znaša 110 ml, kar zagotavlja 100 ml uporabnega volumna.
English: Rifampicin: Concomitant administration of fluconazole and rifampicin resulted in a 25% decrease in the AUC and a 20% shorter half-life of fluconazole.
Slovenian: Rifampicin: Sočasna uporaba flukonazola in rifampicina je za 25 % zmanjšala AUC in za 20 % skrajšala razpolovni čas flukonazola.
English: Plasma elimination half-life for fluconazole is approximately 30 hours.
Slovenian: Razpolovni čas izločanja flukonazola iz plazme znaša približno 30 ur.
English: In patients receiving coumarin-type anticoagulants concurrently with fluconazole the prothrombin time should be carefully monitored.
Slovenian: Pri bolnikih, ki dobivajo antikoagulanse kumarinskega tipa sočasno s flukonazolom, je treba natančno spremljati protrombinski čas.
English: If you get any of the following symptoms, tell your doctor immediately.
Slovenian: Če pri vas pride do pojava katerega izmed spodaj navedenih simptomov, to brez odlašanja povejte svojemu zdravniku.
English: Concomitant use of the following other medicinal products lead to precautions and dose adjustments:
Slovenian: V primeru sočasne uporabe naslednjih zdravil je potrebna previdnost in prilagoditve odmerka:
English: Terfenadine
Slovenian: Terfenadin
English: PHARMACEUTICAL FORM AND CONTENTS 1 hard capsule.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 1 trda kapsula
English: In patients (including paediatric population) with impaired renal function who will receive multiple doses of fluconazole, an initial dose of 50 mg to 400 mg should be given, based on the recommended daily dose for the indication.
Slovenian: Bolnikom (vključno z otroki), ki imajo okvaro ledvic in dobivajo multiple odmerke flukonazola, je treba dati začetni odmerek od 50 mg do 400 mg, izhajajoč iz priporočenega odmerka za določeno indikacijo.
English: • Vaginal candidiasis, acute or recurrent; when local therapy is not appropriate.
Slovenian: • Vaginalne kandidoze, akutne bolezni ali njene ponovitve; kadar lokalno zdravljenje ni primerno.
English: • Prophylaxis of candidal infections in patients with prolonged neutropenia (such as patients with haematological malignancies receiving chemotherapy or patients receiving Hematopoietic Stem Cell Transplantation (see section 5.1)).
Slovenian: • Preprečevanje okužb s kandido pri bolnikih s podaljšano nevtropenijo (kot so bolniki s hematološkimi malignnimi boleznimi, ki prejemajo kemoterapijo ali bolniki, ki prejemajo presadek hematopoetskih zarodnih celic (glejte poglavje 5.1)).
English: Capsule content:
Slovenian: Sestava ovojnice kapsule:
English: 1, 2, 3, 4, 6, 7, 10, 12, 14, 20, 28, 30, 42, 50, 60, 100 or 500 hard capsules.
Slovenian: 1, 2, 3, 4, 6, 7, 10, 12, 14, 20, 28, 30, 42, 50, 60, 100 ali 500 trdih kapsul.
English: After reconstitution, the volume of the suspension is 40 ml, providing a usable volume of 35 ml.
Slovenian: Po rekonstituciji volumen suspenzije znaša 40 ml, kar zagotavlja 35 ml uporabnega volumna.
English: The enzyme inhibiting effect of fluconazole persists 4-5 days after discontinuation of fluconazole treatment due to the long half-life of fluconazole (see section 4.3).
Slovenian: Zaradi dolgega razpolovnega časa flukonazola se njegov zaviralni učinek na encime ohrani še 4 do 5 dni po prenehanju zdravljenja s flukonazolom (glejte poglavje 4.3).
English: Celecoxib: During concomitant treatment with fluconazole (200 mg daily) and celecoxib (200 mg) the celecoxib Cmax and AUC increased by 68% and 134%, respectively.
Slovenian: Celekoksib: Med sočasnim zdravljenjem s flukonazolom (200 mg na dan) in celekoksibom (200 mg) se je Cmax celekoksiba povečala za 68 % in njegova AUC za 134 %.
English: There was no significant pharmacokinetic interaction between fluconazole and azithromycin.
Slovenian: Med flukonazolom in azitromicinom ni bilo pomembnega farmakokinetičnega medsebojnega delovanja.
English: Concomitant use of fluconazole and halofantrine has the potential to increase the risk of cardiotoxicity (prolonged QT interval, torsades de pointes) and consequently sudden heart death.
Slovenian: Sočasna uporaba flukonazola in halofantrina lahko poveča tveganje za pojav kardiotoksičnih učinkov (podaljšanje intervala QT, torsades de pointes) in s tem nenadne srčne smrti.
English: Excipient: 0.58 g sucrose per ml of reconstituted suspension.
Slovenian: Pomožna snov: 0,58 g saharoze na ml rekonstituirane suspenzije.
English: The pharmacokinetic properties of fluconazole are similar following administration by the intravenous or oral route.
Slovenian: Farmakokinetične lastnosti flukonazola so po intravenski in peroralni uporabi podobne.
English: Carcinogenesis
Slovenian: Kancerogenost
English: What Diflucan looks like and contents of the pack Diflucan is a clear, colourless to slightly yellow solution with a viscosity greater than water and is supplied in an amber glass bottle with a screw cap containing 750 mg fluconazole.
Slovenian: Zdravilo Diflucan je bistra, brezbarvna do rahlo rumena raztopina z viskoznostjo večjo kot jo ima voda, na voljo pa je v stekleničkah iz rjavega stekla z navojnim pokrovčkom iz aluminija, v katerih se nahaja 750 mg flukonazola.
English: Write the expiry date of the reconstituted suspension on the bottle label (the shelf life of the reconstituted suspension is 28 days).
Slovenian: Na etiketo plastenke zapišite datum preteka roka uporabnosti rekonstituirane suspenzije (rok uporabnosti rekonstituirane suspenzije je 28 dni).
English: Adults:
Slovenian: Odrasli
English: 150 mg once weekly or 50 mg once daily
Slovenian: 150 mg enkrat na teden ali 50 mg enkrat na dan
English: Methadone: Fluconazole may enhance the serum concentration of methadone.
Slovenian: Metadon: Flukonazol lahko poveča koncentracijo metadona v serumu.
English: Cyclophosphamide: Combination therapy with cyclophosphamide and fluconazole results in an increase in serum bilirubin and serum creatinine.
Slovenian: Ciklofosfamid: Kombinirano zdravljenje s ciklosfosfamidom in flukonazolom povzroči zvišanje ravni bilirubina in kreatinina v serumu.
English: Diflucan has been associated with rare cases of serious hepatic toxicity including fatalities, primarily in patients with serious underlying medical conditions.
Slovenian: V povezavi z zdravilom Diflucan so bili, predvsem pri bolnikih z resnimi osnovnimi boleznimi, opisani redki primeri hude hepatotoksičnosti, tudi s smrtnim izidom.
English: Constipation dyspepsia, flatulence, dry mouth
Slovenian: Zaprtje, dispepsija, flatulenca, suha usta
English: This medicinal product is authorised in the Member States of the EEA under the following names: [See Annex I - To be completed nationally]
Slovenian: Zdravilo je v državah članicah EGP pridobilo dovoljenje za promet z naslednjimi imeni: [glejte dodatek I - Izpolni država članica]
English: Concomitant use of the following other medicinal products is contraindicated:
Slovenian: Sočasna uporaba naslednjih zdravil je kontraindicirana:
English: Instructions for use: Shake the closed bottle of the reconstituted suspension before each use.
Slovenian: Navodila za uporabo: Pred vsako uporabo zaprto plastenko z rekonstituirano suspenzijo stresajte.
English: At doses ranging from 80 mg/kg to 320 mg/kg embryolethality in rats was increased and foetal abnormalities included wavy ribs, cleft palate, and abnormal cranio-facial ossification.
Slovenian: Pri odmerkih, ki so se gibali v območju od 80 mg/kg do 320 mg/kg, je bila smrtnost zarodkov povečana, nenormalnosti pri plodu pa so vključevale valovita rebra, razcepljeno nebo in nenormalno kranio-facialno osifikacijo.
English: A 60 ml bottle contains 24.4 g of powder for oral suspension.
Slovenian: 60 ml plastenka vsebuje 24,4 g praška za peroralno suspenzijo.
English: Consideration should be given to official guidance on the appropriate use of antifungals.
Slovenian: Za ustrezno uporabo protiglivičnih zdravil je treba upoštevati uradne smernice.
English: Fluconazole has been shown to be more selective for fungal cytochrome P-450 enzymes than for various mammalian cytochrome P-450 enzyme systems.
Slovenian: Za flukonazol so ugotovili, da bolj selektivno deluje na encime citokroma P-450 v glivicah kot na encimske sisteme citokroma P-450 pri različnih sesalskih encimskih sistemih.
English: Term newborn infants (0 to 14 days)
Slovenian: Normalno donošeni novorojenčki (0 do 14 dni)
English: Vinca alkaloids: Although not studied, fluconazole may increase the plasma levels of the vinca alkaloids (e.g. vincristine and vinblastine) and lead to neurotoxicity, which is possibly due to an inhibitory effect on CYP3A4.
Slovenian: Alkaloidi vinke: Čeprav tega niso raziskovali, lahko flukonazol poveča koncentracije alkaloidov vinke (npr. vinkristina in vinblastina) v plazmi in povzroči nevrotoksične učinke; to je morda posledica zaviralnega učinka na CYP3A4.
English: In patients with fungal meningitis, fluconazole levels in the CSF are approximately 80% the corresponding plasma levels.
Slovenian: Pri bolnikih z glivičnim meningitisom koncentracija flukonazola v cerebrospinalni tekočini znaša približno 80 % odgovarjajoče koncentracije v plazmi.
English: No adjustments in single dose therapy are necessary.
Slovenian: Pri zdravljenju z enim odmerkom prilagajanje ni potrebno.
English: Taking too much Diflucan may make you unwell.
Slovenian: Če vzamete preveliko količino zdravila Diflucan, bi se lahko počutili slabo.
English: Excipients: each hard capsule also contains 149.12 mg lactose monohydrate.
Slovenian: Pomožne snovi: ena trda kapsula vsebuje tudi 149,12 mg laktoze monohidrata.
English: Patients who are receiving high dose theophylline or who are otherwise at increased risk for theophylline toxicity should be observed for signs of theophylline toxicity while receiving fluconazole.
Slovenian: Bolnike, ki dobivajo velike odmerke teofilina ali jih sicer ogrožajo škodljivi učinki teofilina, je treba med zdravljenjem s flukonazolom opazovati glede znakov škodljivih učinkov teofilina.
English: - Each hard capsule contains 50 mg, 100 mg, 150 mg or 200 mg of fluconazole.
Slovenian: - Ena trda kapsula vsebuje 50 mg, 100 mg, 150 mg ali 200 mg flukonazola.
English: 150 mg every third day for a total of 3 doses (day 1, 4 and 7) and then once a week for 6 months while you are at risk of getting an infection
Slovenian: 150 mg vsak tretji dan do skupno treh odmerkov (1., 4. in 7 dan), nato enkrat na teden dokler pri vas obstaja nevarnost, da bi se lahko okužili
English: In addition to the observed/documented interactions mentioned below, there is a risk of increased plasma concentration of other compounds metabolized by CYP2C9 and CYP3A4 coadministered with fluconazole.
Slovenian: Poleg opaženih/dokumentiranih medsebojnih delovanj, opisanih spodaj, obstaja med sočasno uporabo flukonazola in drugih spojin, ki se presnavljajo s CYP2C9 in CYP3A4, tveganje za povečanje njihove plazemske koncentracije.
English: The coadministration of fluconazole at doses lower than 400 mg per day with terfenadine should be carefully monitored (see sections 4.3 and 4.5).
Slovenian: Bolnike, ki s flukonazolom v odmerkih manjših od 400 mg na dan sočasno prejemajo tudi terfenadin je treba natančno spremljati (glejte poglavji 4.3 in 4.5).
English: For instruction on handling of the product, see section 6.6.
Slovenian: Za navodila glede ravnanja z zdravilom glejte poglavje 6.6.
English: Infants, toddlers and children (from 28 days to 11 years old):
Slovenian: Dojenčki, majhni otroci in otroci (v starosti od 28 dni do 11 let):
English: 7 to 21 days (until oropharyngeal candidiasis is in remission).
Slovenian: 7 do 21 dni (dokler ne pride do remisije kandidoze ustne votline in žrela).
English: The child should remain upright during administration.
Slovenian: Otrok naj med dajanjem zdravila ostane v vzravnanem položaju.
English: The combined use of fluconazole at doses of 400 mg or greater with terfenadine is contraindicated (see section 4.3).
Slovenian: Uporaba flukonazola v odmerkih 400 mg ali več v kombinaciji s terfenadinom je kontraindicirana (glejte poglavje 4.3).
English: Diflucan can be taken with or without food.
Slovenian: Zdravilo Diflucan lahko uporabljamo s hrano ali brez nje.
English: A 60 ml or a 175 ml high density polyethylene (HDPE) bottle with either a plastic child-resistant closure or continuous thread aluminum closure containing a white to off-white powder for oral suspension providing a white to off-white orange-flavoured suspension after reconstitution.
Slovenian: 60 ml ali 175 ml plastenka iz polietilena velike gostote (HDPE), opremljena bodisi s plastičnim zamaškom, ki ga otroci ne morejo odpreti, bodisi z aluminijasto zaporko z neprekinjenim navojem, v kateri se nahaja bel do belkast prašek za peroralno suspenzijo, s katerim po rekonstituciji nastane bela do belkasta suspenzija z okusom po pomarančah.
English: Initial dose: 6 mg/kg Subsequent dose: 3 mg/kg daily
Slovenian: Začetni odmerek: 6 mg/kg Poznejši odmerki: 3 mg/kg na dan
English: Agranulocytosis, leukopenia, thrombocytopenia, neutropenia
Slovenian: Agranulocitoza, levkopenija, trombocitopenija, nevtropenija
English: Fentanyl: One fatal case of fentanyl intoxication due to possible fentanyl fluconazole interaction was reported.
Slovenian: Fentanil: Opisan je bil en primer zastrupitve s fentanilom zaradi možnega medsebojnega delovanja fentanila in flukonazola s smrtnim izidom.
English: To stop cryptococcal meningitis from coming back 200 mg once daily until you are told to stop
Slovenian: Za preprečitev ponovitve kriptokoknega meningitisa 200 mg enkrat na dan, dokler vam zdravnik ne naroči, da z zdravljenjem prenehajte
English: Prophylaxis of candidal infections in patients with prolonged neutropenia
Slovenian: Preprečevanje okužb s kandido pri bolnikih z dolgotrajno nevtropenijo
English: At the 150 mg once-a-week dose, the concentration of fluconazole in stratum corneum on day 7 was 23.4 µg/g and 7 days after the second dose was still 7.1 µg/g.
Slovenian: Pri odmerku 150 mg enkrat na teden je koncentracija flukonazola v stratum corneum 7. dan znašala 23,4 mikrogramov/g, 7 dni po drugem odmerku pa je še vedno znašala 7,1 mikrogramov/g.
English: To treat mucosal thrush - dose depends on where the infection is located
Slovenian: Za zdravljenje glivičnih okužb sluznic - odmerek je odvisen od tega, na katerem mestu se okužba nahaja
English: Concomitant repeated administration of 200 mg fluconazole and 250 mg phenytoin intravenously, caused an increase of the phenytoin AUC24 by 75% and Cmin by 128%.
Slovenian: Sočasno večkratno intravensko dajanje flukonazola v odmerku 200 mg in fenitoina v odmerku 250 mg je povečalo AUC24 fenitoina za 75 % in Cmin za 128 %.
English: Erythromycin: Concomitant use of fluconazole and erythromycin has the potential to increase the risk of cardiotoxicity (prolonged QT interval, torsades de pointes) and consequently sudden heart death.
Slovenian: Eritromicin: Sočasna uporaba flukonazola in eritromicina lahko poveča tveganje za pojav kardiotoksičnih učinkov (podaljšanje intervala QT, torsades de pointes) in s tem nenadne srčne smrti.
English: Elderly Dosage should be adjusted based on the renal function (see “Renal Impairment”).
Slovenian: Starejši Odmerjanje je treba prilagoditi glede na delovanje ledvic (glejte »Okvara ledvic«).
English: Clear Type I glass infusion vial sealed closed with rubber stoppers and aluminium caps.
Slovenian: Infuzijska viala iz prozornega stekla tipa I, neprepustno zaprta z zamaškom iz gume in alumijastim pokrovčkom.
English: Reconstitution instructions:
Slovenian: Navodila za rekonstitucijo:
English: Diflucan treated patients who are concomitantly treated with medicinal products with a narrow therapeutic window metabolised through CYP2C9, CYP2C19 and CYP3A4, should be monitored (see section 4.5).
Slovenian: Bolnike, ki sočasno z zdravilom Diflucan dobivajo zdravila z ozkim terapevtskim oknom, ki se presnavljajo s CYP2C9, CYP2C19 in CYP3A4, je treba spremljati (glejte poglavje 4.5).
English: Because Diflucan is available as a dilute sodium chloride solution, in patients requiring sodium or fluid restriction, consideration should be given to the rate of fluid administration.
Slovenian: Ker je zdravilo Diflucan na voljo v obliki razredčene raztopine natrijevega klorida, je treba pri bolnikih, pri katerih so potrebne omejitve vnosa natrija ali tekočin, pozornost nameniti hitrosti dajanja tekočine.
English: Elderly Dosage should be adjusted based on the renal function (see “Renal impairment”).
Slovenian: Starejši Odmerjanje je treba prilagoditi glede na delovanje ledvic (glejte »Okvara ledvic«)
English: The levels of fluconazole in saliva and sputum are similar to plasma levels.
Slovenian: Koncentracija flukonazola v slini in sputumu je podobna koncentraciji v plazmi.
English: Cardiovascular system
Slovenian: Srčno-žilni sistem
English: Insert the adapter fitted onto the syringe into the bottle neck (Figure 1);
Slovenian: Na brizgi nameščen nastavek vstavite v vrat plastenke (slika 1);
English: 200 mg to 400 mg once daily from 11 months for up to 24 months or longer if needed.
Slovenian: 200 do 400 mg enkrat na dan od 11 do 24 mesecev ali dlje, če je potrebno.
English: Theophylline: In a placebo controlled interaction study, the administration of fluconazole 200 mg for 14 days resulted in an 18% decrease in the mean plasma clearance rate of theophylline.
Slovenian: Teofilin: V s placebom nadzorovani študiji medsebojnega delovanja je 14-dnevna uporaba flukonazola v odmerku 200 mg za 18 % zmanjšala povprečni očistek teofilina iz plazme.