FrancophonIA/ELRC3.0 huggingface dataset:
English: Doses are usually taken within 15 minutes of the meal, but the time may vary from immediately preceding the meal to as long as 30 minutes before the meal.
Slovenian: Odmerek se običajno vzame v 15 minutah pred obrokom, vendar pa se ta čas lahko giblje v razponu od tik pred obrokom do 30 minut pred njim.
English: What you need to know before you take Prandin).
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Prandin).
English: • Steroids (anabolic steroids and corticosteroids - used for anemia or to treat inflammation)
Slovenian: • steroide (anabolne steroide in kortikosteroide, ki jih uporabljamo za zdravljenje anemije ali vnetja),
English: You can take Prandin with metformin, another medicine for diabetes, if your doctor prescribes it.
Slovenian: Zdravilo Prandin lahko jemljete skupaj z metforminom, drugim zdravilom za zdravljenje sladkorne bolezni, če vam takšno zdravljenje predpiše zdravnik.
English: Repaglinide closes ATP-dependent potassium channels in the β-cell membrane via a target protein different from other secretagogues.
Slovenian: Repaglinid v membrani celic β zapre od ATP-odvisne kalijeve kanale, in sicer prek tarčne beljakovine, ki pa ni ista kot pri ostalih sekretagogih.
English: • If severe hypoglycaemia is not treated, it can cause brain damage (temporary or permanent)
Slovenian: • Dolgotrajna nezdravljena huda hipoglikemija lahko povzroči (prehodno ali trajno) okvaro možganov in celo smrt.
English: Repaglinide
Slovenian: repaglinida.
English: If you take more Prandin than you should
Slovenian: Če ste vzeli večji odmerek zdravila Prandin, kot bi smeli
English: When symptoms of hypoglycaemia have disappeared or when blood sugar levels are stabilised continue Prandin treatment.
Slovenian: Ko simptomi hipoglikemije izzvenijo ali se koncentracija krvnega sladkorja ustali, nadaljujte zdravljenje z zdravilom Prandin.
English: • Ciclosporin (used to suppress the immune system)
Slovenian: • ciklosporin (uporabljamo ga za zaviranje imunskega sistema),
English: As insulin sensitivity is increased in diabetic patients with renal impairment, caution is advised when titrating these patients.
Slovenian: Ker je občutljivost za insulin pri diabetikih z okvaro ledvic večja, je prilagajanje odmerka pri teh bolnikih treba opraviti še posebej previdno.
English: • If you exercise more than usual
Slovenian: • če ste telesno bolj dejavni kot ponavadi,
English: • Octreotide (used to treat cancer)
Slovenian: • oktreotid (uporabljamo ga za zdravljenje raka),
English: • Hypersensitivity to repaglinide or to any of the excipients listed in section 6.1.
Slovenian: 4.3 Kontraindikacije • Preobčutljivost za repaglinid ali katero koli pomožno snov, navedeno v poglavju 6.1.
English: Rifampicin, a potent inducer of CYP3A4, but also CYP2C8, acts both as an inducer and inhibitor of the metabolism of repaglinide.
Slovenian: Rifampicin, ki je močan induktor tako CYP3A4 kot CYP2C8, deluje kot induktor in zaviralec presnove repaglinida.
English: Prandin has been shown to lower the blood sugar, which helps to prevent complications from your diabetes.
Slovenian: Zdravilo Prandin dokazano znižuje koncentracijo krvnega sladkorja, kar pomaga preprečiti razvoj zapletov zaradi sladkorne bolezni.
English: The plasma elimination half-life is approximately one hour.
Slovenian: Plazemski razpolovni čas izločanja znaša približno
English: If you forget to take Prandin
Slovenian: Če ste pozabili vzeti zdravilo Prandin
English: Your blood sugar may get too high (hyperglycaemia).
Slovenian: Krvni sladkor se vam lahko tudi preveč zviša (to imenujemo hiperglikemija).
English: • Itraconazole, ketokonazole (antifungal medicines)
Slovenian: • itrakonazol, ketokonazol (zdravila za zdravljenje glivičnih okužb),
English: • If you have liver problems.
Slovenian: • če imate težave z ledvicami.
English: 4.5 Interaction with other medicinal products and other forms of interaction A number of medicinal products are known to influence repaglinide metabolism.
Slovenian: 4.5 Medsebojno delovanje z drugimi zdravili in druge oblike interakcij Na presnovo repaglinida lahko vplivajo številna zdravila, zato mora zdravnik upoštevati možne interakcije.
English: Prandin is an oral antidiabetic medicine containing repaglinide which helps your pancreas produce more insulin and thereby lower your blood sugar (glucose).
Slovenian: Zdravilna učinkovina zdravila Prandin je repaglinid, ki trebušni slinavki pomaga, da tvori več insulina in tako znižuje koncentracijo krvnega sladkorja (glukoze).
English: Since the safety profile of the co-treatment has not been established in these patients, the concomitant use of clopidogrel and repaglinide should be avoided.
Slovenian: Ker pri teh bolnikih profil varnosti sočasnega zdravljenja ni znan, se je sočasni uporabi klopidogrela in repaglinida treba izogibati.
English: Prandin is used to control type 2 diabetes in adults as an add-on to diet and exercise: treatment is usually started if diet, exercise and weight reduction alone have not been able to control (or lower) your blood sugar.
Slovenian: Zdravilo Prandin uporabljamo za obvladovanje sladkorne bolezni tipa 2 pri odraslih bolnikih kot dodatek k dieti in telesni dejavnosti: zdravljenje je treba uvesti, če samo z dieto, telesno dejavnostjo in zmanjšanjem telesne mase koncentracije sladkorja v krvi ni mogoče nadzirati (ali znižati).
English: Novo Nordisk A/S Novo Allé, DK-2880 Bagsværd, Denmark.
Slovenian: Novo Allé, DK-2880 Bagsvaerd, Danska
English: Dosage adjustment of these compounds when co-administered with repaglinide is therefore not necessary.
Slovenian: Prilagoditev odmerka teh zdravil pri sočasni uporabi z repaglinidom ni potrebna.
English: Pharmaco-therapeutic group: Drugs used in diabetes, other blood glucose lowering drugs, excl. insulins, ATC code: A10BX02
Slovenian: Farmakoterapevtska skupina: Drugi antidiabetiki razen insulinov, oznaka ATC: A10BX02.
English: This lack of pharmacodynamic effect was observed with a sub-therapeutic dose of repaglinide.
Slovenian: Tako odsotnost farmakodinamskega učinka so opazili pri odmerkih repaglinida, ki so bili nižji od terapevtskih.
English: Prandin can also be given with metformin, another medicine for diabetes.
Slovenian: Zdravilo Prandin se lahko uporablja tudi skupaj z metforminom, drugim zdravilom za zdravljenje sladkorne bolezni.
English: Allergy is very rare (may affect up to 1 in 10,000 patients).
Slovenian: Alergija Alergija se pojavlja zelo redko (lahko se pojavi pri največ 1 od 10.000 bolnikov).
English: Repaglinide should be taken before main meals (i.e. preprandially).
Slovenian: Način uporabe Bolnik mora repaglinid vzeti pred glavnimi obroki (tj. predprandialno).
English: • If you have type 1 diabetes.
Slovenian: • imate sladkorno bolezen tipa 1,
English: • Danazol (used to treat breast cysts and endometriosis)
Slovenian: • danazol (uporabljamo ga za zdravljenje cist na dojkah in endometrioze),
English: Repaglinide is indicated in adults with type 2 diabetes mellitus whose hyperglycaemia can no longer be controlled satisfactorily by diet, weight reduction and exercise.
Slovenian: 4.1 Terapevtske indikacije Uporaba repaglinida je indicirana pri odraslih bolnikih s sladkorno boleznijo tipa 2, pri katerih hiperglikemije ni več mogoče zadovoljivo obvladovati z dieto, zmanjšanjem telesne mase in s telesno dejavnostjo.
English: NAME OF THE MARKETING AUTHORISATION HOLDER Novo Nordisk A/S
Slovenian: IMETNIK DOVOLJENJA ZA PROMET Novo Nordisk A/S
English: Frequency not known
Slovenian: Neželeni učinki neznane pogostnosti
English: • Phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)
Slovenian: • fenitoin, karbamazepin, fenobarbital (uporabljamo jih pri zdravljenju epilepsije),
English: Repaglinide, like other insulin secretagogues, is capable of producing hypoglycaemia.
Slovenian: Kot drugi sekretagogi insulina lahko tudi repaglinid povzroči hipoglikemijo.
English: The strengths are 0.5 mg, 1 mg and 2 mg. 0.5 mg tablets are white, 1 mg tablets are yellow and 2 mg tablets are peach-coloured.
Slovenian: Tablete so na voljo v treh jakostih: 0,5 mg, 1 mg in 2 mg. 0,5-mg tablete so bele, 1-mg tablete rumene, 2-mg tablete pa breskove barve.
English: SPECIAL STORAGE CONDITIONS Store in the original package in order to protect from moisture
Slovenian: 6.4 Posebna navodila za shranjevanje Shranjujte v originalni ovojnini za zagotovitev zaščite pred vlago.
English: • Thiazides (diuretics or ‘water pills')
Slovenian: • tiazide (diuretiki ali “zdravila za odvajanje vode”),
English: Repaglinide pharmacokinetics are characterised by low volume of distribution, 30 L (consistent with distribution into intracellular fluid) and is highly bound to plasma proteins in humans (greater than
Slovenian: Porazdelitev Za farmakokinetiko repaglinida je značilen majhen volumen porazdelitve (30 l), kar je v skladu s porazdelitvijo v znotrajcelični tekočini, vezava na plazemske proteine pri človeku pa je obsežna (več kot 98 %).
English: • Severe liver problems, abnormal liver function such as increased liver enzymes in your blood.
Slovenian: • hude težave z jetri, moteno delovanje jeter, zvišana koncentracija jetrnih encimov v krvi
English: In vitro data indicate that repaglinide is metabolised predominantly by CYP2C8, but also by CYP3A4.
Slovenian: Podatki in vitro raziskav kažejo, da se repaglinid presnavlja pretežno s CYP2C8, vendar pa tudi s CYP3A4.
English: • Beta blockers (used to treat high blood pressure or heart conditions)
Slovenian: • zaviralce adrenergičnih receptorjev beta (uporabljamo jih za zdravljenje visokega krvnega tlaka ali bolezni srca),
English: Novo Nordisk A/S Novo Allé DK-2880 Bagsværd Denmark
Slovenian: DK-2880 Bagsvaerd Danska
English: • If you have a severe liver disease.
Slovenian: • imate hudo bolezen jeter,
English: • Clopidogrel (prevents blood clots)
Slovenian: • klopidogrel (zdravilo, ki preprečuje nastajanje krvnih strdkov),
English: Repaglinide pharmacokinetics are characterised by a mean absolute bioavailability of 63% (CV 11%).
Slovenian: Za farmakokinetiko repaglinida je značilna 63 % povprečna absolutna biološka uporabnost
English: Abdominal pain, diarrhoea Common Vomiting, constipation Very rare Nausea
Slovenian: Bolezni prebavil bolečina v trebuhu, driska pogosti bruhanje, zaprtost zelo redki navzea neznana
English: Hepatic impairment No clinical studies have been conducted in patients with hepatic insufficiency.
Slovenian: Pri bolnikih z jetrno insuficienco klinične študije niso bile izvedene.
English: Each pack contains 30, 90, 120 or 270 tablets.
Slovenian: 30, 90, 120 ali 270 tablet.
English: Prandin is not recommended in patients with moderate liver disease.
Slovenian: Uporaba zdravila Prandin pri bolnikih z zmerno boleznijo jeter ni priporočljiva.
English: • If you take too much Prandin
Slovenian: • če ste vzeli prevelik odmerek zdravila Prandin,
English: How to store Prandin
Slovenian: Shranjevanje zdravila Prandin
English: • Deferasirox (used to reduce chronic iron overload)
Slovenian: • deferasiroks (uporabljamo ga za zdravljenje kronične preobremenitve z železom),
English: Polacrilin potassium Povidone (polyvidone) Glycerol 85%
Slovenian: glicerol, 85-odstotni magnezijev stearat meglumin poloksamer
English: The following substances may enhance and/or prolong the hypoglycaemic effect of repaglinide: Gemfibrozil, clarithromycin, itraconazole, ketokonazole, trimethoprim, ciclosporin, deferasirox, clopidogrel, other antidiabetic substances, monoamine oxidase inhibitors (MAOI), non selective beta blocking substances, angiotensin converting enzyme (ACE)-inhibitors, salicylates, NSAIDs, octreotide, alcohol, and anabolic steroids.
Slovenian: gemfibrozil, klaritromicin, itrakonazol, ketokonazol, trimetoprim, ciklosporin, deferasiroks, klopidogrel, drugi antidiabetiki, zaviralci monoaminooksidaze (zaviralci MAO), neselektivni antagonisti adrenergičnih receptorjev beta, zaviralci angiotenzinske konvertaze (zaviralci ACE),
English: Prandin 0.5 mg tablets Prandin 1 mg tablets Prandin 2 mg tablets
Slovenian: Navodilo za uporabo Prandin 0,5 mg tablete Prandin 1 mg tablete Prandin 2 mg tablete repaglinid
English: Prandin should not be taken if you have a severe liver disease (see Do not take Prandin).
Slovenian: Bolniki s hudo boleznijo jeter zdravila Prandin ne smejo jemati (glejte podpoglavje Ne jemljite zdravila Prandin);
English: Since the safety profile of this combination has not been established with dosages higher than 0.25 mg for repaglinide and 320 mg for trimethoprim, the concomitant use of trimethoprim with repaglinide should be avoided.
Slovenian: Ker profil varnosti te kombinacije zdravil pri odmerkih, višjih od 0,25 mg za repaglinid in 320 mg za trimetoprim še ni bil ugotovljen, se je treba sočasni uporabi trimetoprima in repaglinida izogibati.
English: • Severe hepatic function disorder.
Slovenian: • Hudo moteno delovanje jeter.
English: • Thyroid products (used to treat low levels of thyroid hormones)
Slovenian: • zdravila za ščitnico (uporabljamo jih za zdravljenje nizke ravni ščitničnih hormonov),
English: METHOD AND ROUTE OF ADMINISTRATION Read the package leaflet before use Oral use
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA Pred uporabo preberite priloženo navodilo.
English: Concomitant use of rifampicin and repaglinide might therefore induce a need for repaglinide dose adjustment which should be based on carefully monitored blood glucose concentrations at both initiation of rifampicin treatment (acute inhibition), following dosing (mixed inhibition and induction), withdrawal (induction alone) and up to approximately two weeks after withdrawal of rifampicin where the inductive effect of rifampicin is no longer present.
Slovenian: tako ob uvedbi zdravljenja z rifampicinom (akutna inhibicija), kot ob nadaljevanju (mešana inhibicija in indukcija) ter ukinitvi zdravljenja (samo indukcija) in še približno do dva tedna po ukinitvi rifampicina, ko indukcijski učinek rifampicina izzveni.
English: Repaglinide is rapidly absorbed from the gastrointestinal tract, which leads to a rapid increase in the plasma concentration of the active substance.
Slovenian: Absorpcija Repaglinid se hitro absorbira iz prebavil, zato se koncentracija zdravilne učinkovine v plazmi hitro zveča.
English: Clinical data in healthy volunteers support CYP2C8 as being the most important enzyme involved in repaglinide metabolism with CYP3A4 playing a minor role, but the relative contribution of CYP3A4 can be increased if CYP2C8 is inhibited.
Slovenian: Klinični podatki, pridobljeni pri zdravih prostovoljcih, potrjujejo domnevo, da je CYP2C8 najpomembnejši encim pri presnovi repaglinida in da ima CYP3A4 pri tem le manjšo vlogo, vendar pa se relativni prispevek CYP3A4 v primeru zavrtja CYP2C8 lahko poveča.
English: Do not take Prandin
Slovenian: Prandin ne smete jemati.
English: Warnings and precautions Talk to your doctor before taking Prandin:
Slovenian: Pred začetkom jemanja zdravila Prandin se posvetujte s svojim zdravnikom:
English: Abnormal hepatic function, increased liver enzymes*
Slovenian: Moteno delovanje jeter, zvišana vrednost jetrnih encimov
English: Embryotoxicity, abnormal limb development in rat foetuses and new born pups, was observed in female rats exposed to high doses in the last stage of pregnancy and during the lactation period.
Slovenian: katerih matere so bile v zadnjem obdobju brejosti in med laktacijo izpostavljene visokim odmerkom repaglinida, so opazili embriotoksične učinke in nenormalen razvoj okončin.
English: Combination with Neutral Protamine Hagedorn (NPH) insulin or thiazolidinediones Trials of combination therapy with NPH insulin or thiazolidinediones have been performed.
Slovenian: Kombinacija z insulinom NPH (Neutral Protamine Hagedorn) ali s tiazolidindioni Preskušanja s kombiniranim zdravljenjem z insulinom NPH ali s tiazolidindioni so bila izvedena, vendar pa je treba profil koristi in tveganj v primerjavi z drugimi kombiniranimi zdravljenji še ugotoviti.
English: The AUC (SD) after 2 mg single dose exposure (4 mg in patients with hepatic insufficiency) was 31.4 ng/ml x hr (28.3) in healthy volunteers, 304.9 ng/ml x hr (228.0) in patients with hepatic insufficiency, and 117.9 ng/ml x hr (83.8) in the elderly type 2 diabetic patients.
Slovenian: Po posamičnem odmerku 2 mg (4 mg pri bolnikih z insuficienco jeter) je vrednost AUC (SD) pri zdravih prostovoljcih znašala 31,4 ng/ml x ura (28,3), pri bolnikih z insuficienco jeter 304,9 ng/ml x ura (228,0), pri starostnikih s sladkorno boleznijo tipa 2 pa 117,9 ng/ml x ura (83,8).
English: Your ability to drive or use a machine may be affected if your blood sugar is low or high.
Slovenian: Previsok ali prenizek krvni sladkor lahko vpliva na sposobnost upravljanja vozil in strojev.
English: Very rare (may affect up to 1 in 10,000 patients)
Slovenian: Zelo redki (pojavijo se lahko pri največ 1 od 10.000 bolnikov)
English: A dose-dependent decrease in blood glucose was demonstrated in type 2 diabetic patients when administered in doses from 0.5 to 4 mg repaglinide.
Slovenian: Pri bolnikih s sladkorno boleznijo tipa 2 so pri uporabi repaglinida v odmerkih od 0,5 do 4 mg dokazali od odmerka odvisno znižanje glukoze v krvi.
English: • Monoamine oxidase inhibitors (MAOI) (used to treat depression)
Slovenian: • zaviralce monoaminooksidaz (zaviralci MAO, uporabljamo jih za zdravljenje depresije),
English: Type 2 diabetes is a disease in which your pancreas does not make enough insulin to control the sugar in your blood or where your body does not respond normally to the insulin it produces.
Slovenian: da bi uravnal koncentracijo sladkorja v krvi ali pa se telo ne odziva normalno na insulin, ki ga proizvaja.
English: Plasma repaglinide levels decreased rapidly, and low concentrations were seen in the plasma of type 2 diabetic patients 4 hours post-administration.
Slovenian: Nizko koncentracijo so v plazmi bolnikov s sladkorno boleznijo tipa 2 ugotovili 4 ure po uporabi.
English: If concomitant use is necessary, careful monitoring of blood glucose and close clinical monitoring should be performed.
Slovenian: Če je sočasna uporaba obeh zdravil nujna, je treba pazljivo nadzirati vrednosti glukoze v krvi in bolnika natančno klinično spremljati.
English: MARKETING AUTHORISATION NUMBERS
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET
English: Co-administration of cimetidine, nifedipine, oestrogen, or simvastatin with repaglinide, all CYP3A4 substrates, did not significantly alter the pharmacokinetic parameters of repaglinide.
Slovenian: nifedipin, estrogen ali simvastatin, se farmakokinetične lastnosti repaglinida niso pomembneje spremenile.
English: Common (may affect up to 1 in 10 patients)
Slovenian: Pogosti (pojavijo se lahko pri največ 1 od 10 bolnikov)
English: The resulting increased calcium influx induces insulin secretion from the β-cell.
Slovenian: Vtok kalcija se zato zveča in to sproži izločanje insulina iz celic β.
English: Abnormal hepatic function, increased liver enzymes Isolated cases of increased liver enzymes have been reported during treatment with repaglinide.
Slovenian: Med zdravljenjem z repaglinidom so poročali o posameznih primerih zvišanja vrednosti jetrnih encimov.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains 0.5 mg of repaglinide.
Slovenian: Ena tableta vsebuje 0,5 mg repaglinida.
English: • Clarithromycin, trimethoprim, rifampicin (antibiotic medicines)
Slovenian: • simpatikomimetike (uporabljamo jih za zdravljenje astme), • klaritromicin, trimetoprim, rifampicin (antibiotiki),
English: They include: increased urination; feeling thirsty; dry skin and dry mouth.
Slovenian: Opozorilni znaki previsokega krvnega sladkorja se pojavijo postopoma in vključujejo: pogostejše uriniranje, občutek žeje, suho kožo in suha usta.
English: Prandin should be taken with caution.
Slovenian: V tem primeru morate zdravilo Prandin uporabljati previdno;
English: INFORMATION IN BRAILLE prandin 0.5 mg
Slovenian: prandin 0,5 mg
English: • If you take gemfibrozil (a medicine used to lower increased fat levels in the blood).
Slovenian: • jemljete gemfibrozil (zdravilo za zdravljenje zvišane koncentracije maščob v krvi).
English: - The other ingredients are microcrystalline cellulose (E460), calcium hydrogen phosphate anhydrous, maize starch, polacrilin potassium, povidone (polyvidone), glycerol 85%, magnesium stearate, meglumine, poloxamer, iron oxide yellow (E172) only in the 1 mg tablets and iron oxide red (E172) only in the 2 mg tablets.
Slovenian: - Pomožne snovi so: mikrokristalna celuloza (E460), brezvodni kalcijev hidrogenfosfat, koruzni škrob, polakrilin kalij, povidon (polividon), 85-odstotni glicerol, magnezijev stearat, meglumin,
English: Less than 1% of repaglinide is recovered in faeces.
Slovenian: Z blatom se izloči manj kot 1 %
English: It has not been studied in these age groups.
Slovenian: Uporaba zdravila Prandin ni priporočljiva, saj njegova uporaba v teh starostnih skupinah ni bila raziskana.
English: Special care should be taken when inhibitors of both CYP2C8 and 3A4 are co-administered simultaneously with repaglinide.
Slovenian: Posebna previdnost je potrebna v primeru sočasne uporabe repaglinida in zdravil, ki zavirajo tako CYP2C8 kot 3A4.
English: If your blood sugar gets too high
Slovenian: V primeru prekomernega zvišanja koncentracije krvnega sladkorja
English: INFORMATION IN BRAILLE prandin 2 mg
Slovenian: prandin 2 mg
English: • If you have an infection or a fever
Slovenian: • če imate okužbo ali zvišano telesno temperaturo, • če jeste več kot ponavadi,
English: • Gemfibrozil (used to treat high blood fats)
Slovenian: • gemfibrozil (zdravilo za zdravljenje zvišane koncentracije maščob v krvi),
English: You may get a hypo (short for hypoglycaemia) if your blood sugar gets too low.
Slovenian: V primeru pojava hipe (nizka koncentracija krvnega sladkorja) Če se vam krvni sladkor prekomerno zniža, lahko doživite hipo (hipa je okrajšava za hipoglikemijo in pomeni simptome nizkega krvnega sladkorja).
English: Co-administration of trimethoprim (160 mg twice daily), a moderate CYP2C8 inhibitor, and repaglinide (a single dose of 0.25 mg) increased the repaglinide AUC, Cmax and t½ (1.6-fold, 1.4-fold and 1.2-fold respectively) with no statistically significant effects on the blood glucose levels.
Slovenian: Pri sočasni uporabi trimetoprima (v odmerku 160 mg dvakrat na dan), srednje močnega zaviralca CYP2C8, in repaglinida (v enkratnem odmerku 0,25 mg), se je vrednost AUC repaglinida povečala za 1,6-krat, vrednost Cmax za 1,4-krat, vrednost t½ pa za 1,2-krat, brez statistično pomembnega vpliva na vrednosti glukoze v krvi.
English: MARKETING AUTHORISATION NUMBERS EU/1/00/162/009-11, EU/1/00/162/020
Slovenian: ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/00/162/009-011, EU/1/00/162/020
English: INFORMATION IN BRAILLE prandin 1 mg
Slovenian: prandin 1 mg
English: Co-administration of gemfibrozil (600 mg twice daily), an inhibitor of CYP2C8, and repaglinide (a single dose of 0.25 mg) increased the repaglinide AUC 8.1-fold and Cmax 2.4-fold in healthy volunteers.
Slovenian: Pri sočasni uporabi gemfibrozila (v odmerku 600 mg dvakrat na dan), zaviralca CYP2C8, in repaglinida (v enkratnem odmerku 0,25 mg), se je pri zdravih prostovoljcih vrednost AUC repaglinida povečala za 8,1-krat, vrednost Cmax pa za 2,4-krat.
English: EU/1/00/162/009 30 tablets EU/1/00/162/010 90 tablets EU/1/00/162/011 120 tablets EU/1/00/162/020 270 tablets
Slovenian: EU/1/00/162/009 30 tablet EU/1/00/162/010 90 tablet EU/1/00/162/011 120 tablet EU/1/00/162/020 270 tablet
English: If you take gemfibrozil (used to lower increased fat levels in the blood) you should not take Prandin.
Slovenian: Če jemljete gemfibrozil (zdravilo za zdravljenje zvišane koncentracije maščob v krvi), zdravila
English: What Prandin contains
Slovenian: Eno pakiranje vsebuje
English: EU/1/00/162/015 30 tablets EU/1/00/162/016 90 tablets EU/1/00/162/017 120 tablets EU/1/00/162/019 270 tablets
Slovenian: EU/1/00/162/015 30 tablet EU/1/00/162/016 90 tablet EU/1/00/162/017 120 tablet EU/1/00/162/019 270 tablet
English: EU/1/00/162/003 30 tablets EU/1/00/162/004 90 tablets EU/1/00/162/005 120 tablets EU/1/00/162/021 270 tablets
Slovenian: EU/1/00/162/003 30 tablet EU/1/00/162/004 90 tablet EU/1/00/162/005 120 tablet EU/1/00/162/021 270 tablet