FrancophonIA/ELRC3.0 huggingface dataset:
English: No information on the tolerability of tolcapone in these populations is available (see section 5.2)
Croatian: Nisu dostupni podaci o podnošljivosti tolkapona u ovim populacijama (vidjeti dio 5.2)
English: Film-coat: Hydroxypropylmethylcellulose, Talc, Yellow iron oxide, Ethylcellulose, Titanium dioxide, Triacetin, Sodium lauril sulfate.
Croatian: Film ovojnica: hidroksipropilmetilceluloza, talk, žuti željezov oksid, etilceluloza, titanijev dioksid, triacetin, natrijev laurilsulfat.
English: o
Croatian: I
English: During treatment: Liver function should be monitored every 2 weeks for the first year of therapy, every 4 weeks for the next 6 months and every 8 weeks thereafter.
Croatian: Tijekom liječenja: funkciju jetre treba nadzirati svaka 2 tjedna tijekom prve godine terapije, svaka 4 tjedna tijekom sljedećih 6 mjeseci te svakih 8 tjedana nakon toga.
English: “TASMAR” and “200” are engraved on one side.
Croatian: “TASMAR” i “200” su ugravirani na jednoj strani.
English: Increases to more than three times the upper limit of normal (ULN) in alanine aminotransferase (ALT)occurred in 1 % of patients receiving Tasmar 100 mg three times daily, and 3 % of patients at 200 mg three times daily.
Croatian: Povećanja na više od tri puta od gornje granice normale (GGN) u alanin aminotransferazi (ALT) javila su se u 1 % bolesnika koji su primali Tasmar 100 mg tri puta dnevno i 3 % bolesnika koji su primali 200 mg tri puta dnevno.
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, 4.2)
Croatian: Lijek se izdaje na ograničeni recept (vidjeti Dodatak I: Sažetak opisa svojstava lijeka, dio 4.2)
English: The consequent increase in dopaminergic stimulation can lead to the dopaminergic adverse reactions observed after treatment with COMT inhibitors.
Croatian: Posljedično povećanje dopaminergičke stimulacije može voditi do dopaminergičkih nuspojava opaženih nakon liječenja COMT inhibitorima.
English: severe symptoms of muscle stiffening, fever or mental confusion (Neuroleptic Malignant Syndrome) when antiparkinsonian treatments are abruptly reduced or withdrawn - Impulse control disorders (inability to resist the impulse of an action that could be harmful).
Croatian: Rijetko: - teški simptomi ukočenosti mišića, vrućica ili mentalna smetenost (neuroleptički maligni sindrom) kada se liječenje lijekovima za Parkinsonovu bolest naglo smanji ili ukine - poremećaj kontrole impulsa (nemogućnost odupiranja impulsu za neki postupak koji može biti štetan)
English: Tolcapone's effect on levodopa pharmacokinetics is similar with all pharmaceutical formulations of levodopa/benserazide and levodopa/carbidopa; it is independent of levodopa dose, levodopa/AADC-I (benserazide or carbidopa) ratio and the use of sustained-release formulations.
Croatian: Učinak tolkapona na farmakokinetiku levodope sličan je kod svih farmaceutskih oblika levodope/benzerazida i levodope/karbidope; neovisan je o dozi levodope, omjeru levodope/AADC-I (benzerazid ili karbidopa) te primjeni oblika s produljenim oslobađanjem.
English: Neuroleptic Malignant Syndrome Symptom Complex
Croatian: Grupa simptoma neuroleptičkog malignog sindroma
English: Special populations: Patients with severe renal impairment (creatinine clearance <30 ml/min) should be treated with caution.
Croatian: Posebne populacije: bolesnike s teškim oštećenjem jetre (klirens kreatinina <30 ml/min) treba liječiti s oprezom.
English: The data of more than 400 patients have confirmed that over a wide range of creatinine clearance values (30-130 mL/min) the pharmacokinetics of tolcapone are unaffected by renal function.
Croatian: Podaci o više od 400 bolesnika potvrdili su da bubrežna funkcija ne utječe na farmakokinetiku tolkapona kroz široki raspon vrijednosti klirensa kreatinina (30130 ml/min).
English: Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed (non-prescription medicines and herbals).
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzeli bilo koje druge lijekove, uključujući i one koji nisu propisani (bezreceptne i biljne lijekove).
English: Diarrhoea: In clinical trials, diarrhoea developed in 16 % and 18 % of patients receiving Tasmar 100 mg tid and 200 mg tid respectively, compared to 8 % of patients receiving placebo.
Croatian: Proljev: u kliničkim ispitivanjima, proljev je razvilo 16 % i 18 % bolesnika koji su uzimali Tasmar 100 mg tri puta dnevno, odnosno 200 mg tri puta dnevno, u usporedbi s 8 % bolesnika koji su primali placebo.
English: If treatment is discontinued: Patients who show evidence of acute liver injury while on Tasmar and are withdrawn from the medicinal product may be at increased risk for liver injury if Tasmar is reintroduced.
Croatian: Ako se prekida liječenje: bolesnici koji pokazuju znakove akutnog oštećenja jetre dok su na Tasmaru i koji prestanu uzimati taj lijek mogu imati povećani rizik od oštećenja jetre kod ponovnog uvođenja Tasmara.
English: This may include: o
Croatian: To može uključivati:
English: The treatment will be stopped, if these blood tests become abnormal.
Croatian: Ako ovi krvni nalazi budu abnormalni, liječenje će biti prekinuto.
English: Tell your doctor or a pharmacist as soon as possible: if you do not feel well while you are taking Tasmar if you experience symptoms such as nausea, vomiting, abdominal pain, loss of appetite, weakness, fever, darkening of urine or jaundice since uncommonly disturbances in the way the liver works, sometimes severe hepatitis was observed, if you notice a darkening of your urine since this could be a sign of a muscular or liver injury.
Croatian: Obavijestite svog liječnika ili ljekarnika što je prije moguće: - ako se ne osjećate dobro dok uzimate Tasmar - ako imate simptome kao što su mučnina, povraćanje, bol u trbuhu, gubitak apetita, slabost, vrućica, tamnija mokraća ili žutica jer su manje često opaženi poremećaji u načinu rada jetre, a ponekad i teški hepatitis, - ako primijetite da Vam je mokraća tamnija jer to može bit znak mišićnog ili jetrenog oštećenja.
English: Marketing Authorisation Holder: Meda AB
Croatian: Nositelj odobrenja za stavljanje gotovoga lijeka u promet Meda AB
English: The consequent increase in dopaminergic stimulation can lead to the dopaminergic side effects observed after treatment with COMT inhibitors.
Croatian: Posljedično povećanje dopaminergičke stimulacije može dovesti do dopaminergičkih nuspojava opaženih nakon liječenja COMT inhibitorima.
English: A natural protein (enzyme) in your body, the (COMT) Catechol-O-methyltransferase in your body breaks down levodopa.
Croatian: Prirodni protein (enzim) u Vašem tijelu, katehol-O-metiltransferaza (engl. catechol-Omethyltransferase, (COMT) razgrađuje levodopu u Vašem tijelu.
English: Because of the risk of rare but potentially fatal acute liver injury, Tasmar is only indicated for use in patients with levodopa-responsive idiopathic Parkinson's disease and motor fluctuations, who failed to respond to or are intolerant of other COMT inhibitors.
Croatian: Oštećenje jetre: zbog rizika od rijetkog, ali potencijalno smrtonosnog, akutnog oštećenja jetre, Tasmar je indiciran samo za primjenu u bolesnika s idiopatskom Parkinsonovom bolešću koja odgovara na levodopu i motoričkim fluktuacijama, a koji nisu odgovarali ili su intolerantni na druge COMT inhibitore.
English: Since clinical information is limited regarding the combination of warfarin and tolcapone, coagulation parameters should be monitored when these drugs are co-administered.
Croatian: Budući da su klinički podaci koji se odnose na kombinaciju varfarina i tolkapona ograničeni, parametri koagulacije se moraju nadzirati kada se ovi lijekovi primjenjuju istodobno.
English: If benefits are not seen within 3 weeks of the initiation of the treatment, Tasmar should be discontinued.
Croatian: Ako se unutar 3 tjedna od početka liječenja ne vide koristi, liječenje Tasmarom treba prekinuti.
English: Patients with severe renal impairment (creatinine clearance <30 ml/min) should be treated with caution.
Croatian: Bolesnike s teškim oštećenjem bubrega (klirens kreatinina <30 ml/min) treba liječiti s oprezom.
English: If the dose is increased to 200 mg tid, liver enzyme monitoring should take place before increasing the dose and then be reinitiated following the same sequence of frequencies as above (see sections 4.4 and 4.8).
Croatian: Ako se doza poveća na 200 mg tri puta dnevno, prije povećanja doze treba nadzirati jetrene enzime, a zatim ponovno nadzirati prema jednakom slijedu učestalosti koji je naveden gore (vidjeti dijelove 4.4 i 4.8).
English: The most common of these are increased dyskinesia, nausea, vomiting, abdominal pain, syncope, orthostatic complains, constipation, sleep disorders, somnolence, hallucination.
Croatian: Najčešće od njih su pojačana diskinezija, mučnina, povraćanje, bol u abdomenu, sinkopa, ortostatske smetnje, konstipacija, poremećaji spavanja, somnolencija, halucinacije.
English: Outer Carton and bottle label, 30, 60, 100, 200 film-coated tablets
Croatian: Kartonska kutija i naljepnica na bočici, 30, 60, 100, 200 filmom obloženih tableta
English: A natural protein (enzyme) in your body, the (COMT) Catechol-O-methyltransferase breaks down the levodopa.
Croatian: Prirodni protein (enzim) u Vašem tijelu, katehol-O-metiltransferaza (engl. catechol-Omethyltransferase, (COMT) razgrađuje levodopu.
English: Liver function should be checked before starting treatment with Tasmar and then monitored every 2 weeks for the first year of therapy, every 4 weeks for the next 6 months and every 8 weeks thereafter.
Croatian: Prije liječenja Tasmarom treba provjeriti jetrenu funkciju, a zatim je nadzirati svaka 2 tjedna tijekom prve godine terapije, svaka 4 tjedna tijekom sljedećih 6 mjeseci i svakih 8 tjedana nakon toga.
English: Plasma levels of 3OMD were markedly and dose-dependently decreased by tolcapone when given with levodopa/AADC-I (aromatic amino acid decarboxylase - inhibitor) (benserazide or carbidopa).
Croatian: Tolkapon je značajno i ovisno o dozi smanjio plazmatske razine 3-OMD-a kada se davao s levodopom/AADC-I (inhibitor dekarboksilaze aromatske aminokiseline) (benzerazid ili karbidopa).
English: Česká republika MEDA Pharma s.r.o.
Croatian: Slovenská republika MEDA Pharma spol. s. r.o.
English: While receiving treatment:
Croatian: Tijekom liječenja:
English: Outer Carton and blister packs, 30 and 60 film-coated tablets
Croatian: Vanjska kutija i blister pakiranja, 30 i 60 filmom obloženih tableta
English: Diarrhoea led to withdrawal of 5% and 6% of patients receiving Tasmar 100 mg tid and 200 mg tid respectively, compared to 1 % of patients receiving placebo.
Croatian: Proljev je doveo do odustajanja kod 5 % i 6 % bolesnika koji su primali Tasmar 100 mg tri puta dnevno, odnosno 200 mg tri puta dnevno, u usporedbi s 1 % bolesnika koji su primali placebo.
English: C/Plom, 2-4, 5ª planta 08038 - Barcelona Tel: +34 900 102 712
Croatian: Mylan Pharmaceuticals S.L. C/Plom, 2-4, 5ª planta 08038 - Barcelona Tel: +34 900 102 712
English: Mylan Healthcare B.V Krijgsman 20
Croatian: Mylan Healthcare B.V
English: To improve efficacy your doctor should only increase the dose to 3 times daily 2 tablets (200 mg three times a day) if the increase in how your Parkinson´s disease symptoms are controlled outweighs the expected increase in side effects.The side effects at the higher dose can often be severe and affect your liver.
Croatian: Kako bi poboljšao učinkovitost Vaš liječnik smije dozu povećati samo na 3 puta dnevno po 2 tablete (200 mg tri puta dnevno), ako poboljšanje u kontroliranju simptoma Parkinsonove bolesti nadjačava očekivano pojačanje nuspojava.
English: Rare (≥1/10,000 to < 1/1,000)
Croatian: Rijetko (≥1/10 000 i < 1/1000)
English: If the dose is increased to 200 mg tid, liver enzyme monitoring should take place before increasing the dose and then be re-initiated following the sequence of frequencies as above.
Croatian: Ako se doza poveća na 200 mg tri puta dnevno, prije povećanja doze treba nadzirati jetrene enzime, a zatim ponovno nadzirati prema jednakom slijedu učestalosti koji je naveden gore.
English: 30 film-coated tablets 60 film-coated tablets
Croatian: 30 filmom obloženih tableta 60 filmom obloženih tableta
English: It is available in blisters in pack sizes of 30 and 60 tablets and in glass bottles in pack sizes of 100 tablets.
Croatian: Dostupne su u blisterima u veličinama pakiranja od 30 i 60 tableta te u staklenim bočicama u veličinama pakiranja od 100 tableta.
English: In the therapeutic range, tolcapone pharmacokinetics are linear and independent of levodopa/AADC-I (benserazide or carbidopa) coadministration.
Croatian: U terapijskom rasponu, farmakokinetika tolkapona je linearna i neovisna o istodobnoj primjeni levodope/AADC-I (benzerazid ili karbidopa).
English: Tasmar is available in PVC/PE/PVDC blisters (pack sizes of 30 and 60 film-coated tablets) and in amber glass bottles without desiccant (pack sizes of 100 film-coated tablets).
Croatian: Tasmar je dostupan u PVC/PE/PVDC blisterima (veličine pakiranja od 30 i 60 filmom obloženih tableta) i u staklenim bočicama boje jantara bez sredstva za sušenje (veličine pakiranja od 100 filmom obloženih tableta).
English: severe symptoms of muscle stiffening, fever or mental confusion (Neuroleptic Malignant Syndrome) when antiparkinsonian treatments are abruptly reduced or withdrawn.
Croatian: Rijetko: - teški simptomi ukočenosti mišića, vrućica ili mentalna smetenost (neuroleptički maligni sindrom) kada se liječenje lijekovima za Parkinsonovu bolest naglo smanji ili ukine
English: It is available in blisters in pack sizes of 30 and 60 tablets and in glass bottles in pack sizes of 30, 60 ,100 and 200 filmcoated tablets.
Croatian: Dostupne su u blisterima u veličinama pakiranja od 30 i 60 tableta te u staklenim bočicama u veličinama pakiranja od 30, 60, 100 i 200 filmom obloženih tableta.
English: may affect more than 1 in 10 people
Croatian: mogu se javiti u više od 1 na 10 osoba
English: Pale to light yellow, hexagonal, biconvex, film-coated tablet.
Croatian: Blijeda do svijetložuta, heksagonalna, bikonveksna, filmom obložena tableta.
English: Warfarin: Since clinical information is limited regarding the combination of warfarin and tolcapone, coagulation parameters should be monitored when these drugs are co-administered.
Croatian: Varfarin: budući da je kliničko iskustvo s kombinacijom varfarina i tolkapona ograničeno, trebalo bi nadzirati parametre koagulacije kada se ovi lijekovi primjenjuju istodobno.
English: Tasmar is indicated in combination with levodopa/benserazide or levodopa/carbidopa for use in patients with levodopa-responsive idiopathic Parkinson's disease and motor fluctuations, who failed to respond to or are intolerant of other catechol-o-methyltransferase (COMT) inhibitors (see section 5.1).
Croatian: Tasmar je indiciran u kombinaciji s levodopom/benzerazidom ili levodopom/karbidopom za primjenu u bolesnika s idiopatskom Parkinsonovom bolešću koja odgovara na levodopu i motoričkim fluktuacijama, a koji nisu odgovarali ili su intolerantni na druge inhibitore katehol-O-metiltransferaze (COMT, engl. catechol-O-methyltransferase) (vidjeti dio 5.1).
English: EU/1/97/044/006 100 tablets
Croatian: EU/1/97/044/006 100 tableta
English: Rare cases of severe hepatocellular injury resulting in death have been reported during marketed use (see section 4.4).
Croatian: Tijekom tržišne primjene prijavljeni su rijetki slučajevi hepatocelularnog oštećenja sa smrtnim ishodom (vidjeti dio 4.4).
English: How to store Tasmar
Croatian: Kako čuvati Tasmar
English: Hepatocellular injury, in rare cases with fatal outcome* (see section 4.4)
Croatian: Poremećaji jetre i žuči manje često hepatocelularno oštećenje, u rijetkim slučajevima s fatalnim ishodom (vidjeti dio 4.4)
English: Skin and subcutaneous tissue disorders
Croatian: Poremećaji kože i potkožnog tkiva često pojačano znojenje
English: EU/1/97/044/007 30 tablets EU/1/97/044/008 60 tablets EU/1/97/044/003 100 tablets EU/1/97/044/0010 200 tablets
Croatian: EU/1/97/044/007 30 tableta EU/1/97/044/008 60 tableta EU/1/97/044/003 100 tableta EU/1/97/044/0010 200 tableta
English: Tasmar is available in PVC/PE/PVDC blisters (pack sizes of 30 and 60 film-coated tablets) and in amber glass bottles without desiccant (pack sizes of 30, 60,100 and 200 film-coated tablets).
Croatian: Tasmar je dostupan u PVC/PE/PVDC blisterima (veličine pakiranja od 30 i 60 filmom obloženih tableta) i u staklenim bočicama boje jantara bez sredstva za sušenje (veličine pakiranja od 30, 60, 100 i 200 filmom obloženih tableta).
English: The following suggestions are based on pharmacological considerations and have not been evaluated in clinical trials.
Croatian: Prilagodbe levodope pri ukidanju Tasmara: sljedeće sugestije temelje se na farmakološkim razmatranjima te nisu vrednovane u kliničkim ispitivanjima.
English: Common (≥1/100 to < 1/10)
Croatian: Često (≥1/100 i < 1/10)
English: Impulse control disorders: Pathological gambling, increased libido, hypersexuality, compulsive spending or buying, binge eating and compulsive eating can occur in patients treated with dopamine agonists and/or other dopaminergic treatments such as Tasmar in association with Levedopa (see section 4.4 `special warnings and precautions for use´).
Croatian: Poremećaji kontrole impulsa: u bolesnika liječenih agonistima dopamina i/ili drugim dopaminergičkim liječenjima kao što je Tasmar u kombinaciji s levodopom može se javiti patološko kockanje, pojačani libido, hiperseksualnost, kompulzivno trošenje ili kupovanje, prejedanje i kompulzivno jedenje (vidjeti dio 4.4 `posebna upozorenja i mjere opreza pri uporabi´).
English: However, Tasmar, as a COMT inhibitor, is known to increase the bioavailability of the co-administered levodopa.
Croatian: Međutim, poznato je da Tasmar, kao COMT inhibitor, povećava bioraspoloživost istodobno primijenjene levodope.
English: Tasmar is supplied as film-coated tablets containing 100 mg tolcapone.
Croatian: Tasmar se isporučuje kao filmom obložene tablete koje sadrže 100 mg tolkapona.
English: System organ class
Croatian: Klasifikacija organskih sustava Incidencija
English: Tasmar is supplied as film-coated tablets containing 200 mg tolcapone.
Croatian: Tasmar se isporučuje kao filmom obložene tablete koje sadrži 200 mg tolkapona.
English: Tasmar, as a COMT inhibitor, is known to increase the bioavailability of the co-adminstered levodopa.
Croatian: Poznato je da Tasmar, kao COMT inhibitor, povećava bioraspoloživost istodobno primijenjene levodope.
English: A previous history of Neuroleptic Malignant Syndrome (NMS) Symptom Complex and /or non-traumatic Rhabdomyolysis or Hyperthermia.
Croatian: • Anamneza grupe simptoma neuroleptičnog malignog sindroma (NMS) i /ili netraumatske rabdomiolize ili hipertermije.
English: Excipients with known effect: Each tablet contains 7.5 mg lactose For the full list of excipients, see section 6.1.
Croatian: Pomoćne tvari s poznatim učinkom: svaka tableta sadrži 7,5 mg laktoze
English: may affect up to 1 in 1,000 people
Croatian: mogu se javiti u do 1 na 1000 osoba
English: Transient elevation above pretreatment levels of erythrocyte COMT activity was observed after withdrawal of tolcapone.
Croatian: Nakon prekida liječenja tolkaponom opažena su prolazna povišenja aktivnosti eritrocitnog COMT-a viša od razina prije liječenja.
English: Also contains lactose See leaflet for further information.
Croatian: Vidjeti Uputu o lijeku za dodatne informacije.
English: Dose and frequency of administration
Croatian: Doza i učestalost primjene
English: Postepu 21 B 02-676 Warszawa Tel: +48 22 5466400
Croatian: Mylan Healthcare Sp.z.o.o. ul. Postepu 21 B 02-676 Warszawa Tel: +48 22 5466400
English: Tolcapone does not accumulate with three times daily dosing of 100 or 200 mg. At these doses, Cmax is approximately 3 and 6 µg/ml, respectively.
Croatian: Tolkapon se ne akumulira s dozama od 100 do 200 mg tri puta dnevno.
English: 100 film-coated tablets
Croatian: 100 filmom obloženih tableta.
English: Slovenská republika MEDA Pharma spol.
Croatian: Slovenská republika MEDA Pharma spol. s r.o.
English: Tablet core: Calcium hydrogen phosphate, Microcrystalline cellulose, Povidone K30, Sodium starch glycollate, Lactose, Talc, Magnesium stearate.
Croatian: - Drugi sastojci su: Jezgra tablete: kalcijev hidrogenfosfat, mikrokristalična celuloza, povidon K30, natrijev škroboglikolat, laktoza, talk, magnezijev stearat.
English: Meda Pharma S.p.A.
Croatian: MEDA Pharmaceuticals A.E.
English: In Parkinson`s patients, NMS tends to occur when discontinuing or stopping dopaminergic-enhancing medications.
Croatian: Neuroleptični maligni sindrom (NMS): u bolesnika s Parkinsonovom bolešću, NMS se obično javlja pri prekidu ili prestanku uzimanja lijekova koji povećavaju dopaminergičku aktivnost.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer carton for blister packs [ 30 and 60 film-coated tablets]
Croatian: Kartonska kutija za blister pakiranje [ 30 i 60 filmom obloženih tableta]
English: Very common: involuntary movement (dyskinesia), nausea, decreased appetite, diarrhoea, headache, dizziness sleep problems, somnolence, feeling lightheaded while you stand, (orthostatic complaints),mental confusion and hallucinations, movement disorder with involuntary muscle spasms or malpositions (dystonia), dreaming excessive.
Croatian: Vrlo često: - nevoljni pokreti (diskinezija), - mučnina, gubitak apetita, proljev, - glavobolja, omaglica - poremećaji spavanja, izrazita pospanost, - osjećaj ošamućenosti dok stojite (ortostatske smetnje), mentalna smetenost i halucinacije - poremećaj pokreta s nevoljnim mišićnim grčevima ili iskrivljenim položajima (distonija) - prekomjerno sanjanje
English: Common: chest pain, constipation, dyspepsia, stomach ache, vomiting, dry mouth, fainting increased sweating, influenza-like symptoms reduced voluntary and involuntary movement (hypokinesia) upper respiratory tract infection increase of specific liver enzymes, urine discoloration
Croatian: Često: - bol u prsnom košu, - zatvor, probavne tegobe, želučana bol, povraćanje, suha usta - nesvjestica - pojačano znojenje, - simptomi nalik gripi - smanjenje voljnih i nevoljnih pokreta (hipokinezija) - infekcija gornjih dišnih puteva - povećanje specifičnih enzima jetre - promjena boje urina
English: Upper respiratory tract infection
Croatian: Infekcije i infestacije često infekcija gornjeg respiratornog trakta
English: may affect up to 1 in 100 people
Croatian: mogu se javiti u do 1 na 100 osoba
English: For the treatment of Parkinson´s disease, Tasmar is used together with the medicinal product levodopa (as levodopa/benserazide or levodopa/carbidopa).
Croatian: Tasmar se koristi zajedno s levodopom (kao levodopa/benzerazid ili levodopa/karbidopa) za liječenje Parkinsonove bolesti.
English: As Tasmar decreases the breakdown of levodopa in the body, side effects due to increased levodopa concentrations may occur when beginning Tasmar treatment.
Croatian: Prilagodbe levodope tijekom liječenja Tasmarom: budući da Tasmar smanjuje razgradnju levodope u tijelu, pri početku liječenja Tasmarom mogu se javiti nuspojave zbog povišenih koncentracija levodope.
English: Binge eating (eating large amounts of food in a short time period) or compulsive eating (eating more food than normal and more than needed to satisfy your hunger).
Croatian: o snažan impuls za prekomjernim kockanjem unatoč ozbiljnim osobnim ili obiteljskim posljedicama o promijenjen ili povećan spolni interes i ponašanje koje značajno zabrinjava vas ili druge, na primjer, pojačani spolni nagon o nekontrolirano prekomjerno kupovanje ili trošenje o prejedanje (jedenje velikih količina hrane u kratkom vremenskom razdoblju) ili kompulzivno jedenje (jedenje više hrane nego što je normalno i više nego što je potrebno za zadovoljenje gladi).
English: Uncommon (≥1/1,000 to < 1/100)
Croatian: Manje često (≥1/1000 i < 1/100)
English: may affect up to 1 in 10,000 people
Croatian: mogu se javiti u do 1 na 10 000 osoba
English: EU/1/97/044/004 30 tablets EU/1/97/044/005 60 tablets
Croatian: EU/1/97/044/004 30 tableta EU/1/97/044/005 60 tableta