FrancophonIA/ELRC3.0 huggingface dataset:
English: This may reduce your risk of early death or catching infections because your immune system is weak.
Danish: Dette kan gøre dit immunforsvar stærkere og kan nedsætte din risiko for tidlig død eller for at få infektioner, som følge af at dit immunforsvar er svækket.
English: Delstrigo should be avoided with concurrent or recent use of nephrotoxic medicinal products (e.g., high-dose or multiple nonsteroidal anti-inflammatory medicinal products [NSAIDs]) (see section 4.5).
Danish: Delstrigo skal undgås sammen med eller ved nylig anvendelse af nefrotoksiske lægemidler (f.eks. høje doser af eller flere non-steroide antiinflammatoriske lægemidler [NSAID]) (se pkt.
English: Rare musculoskeletal pain, osteomalacia (manifested as bone pain and infrequently contributing to fractures)*, myopathy*
Danish: Sjælden muskuloskeletale smerter, osteomalaci (manifesteret som knoglesmerter og i sjældne tilfælde med frakturer til følge)*, myopati*
English: Tenofovir disoproxil requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate.
Danish: Tenofovirdisoproxil kræver først diesterhydrolyse for at blive omdannet til tenofovir og efterfølgende fosforyleringer via cellulære enzymer for at blive til tenofovirdifosfat.
English: There was no clinically relevant difference in the pharmacokinetics of doravirine in a study comparing 8 subjects with moderate hepatic impairment (classified as Child-Pugh score B primarily due to increased encephalopathy and ascites scores) to 8 subjects without hepatic impairment.
Danish: Der var ingen klinisk relevant forskel i doravirins farmakokinetik i et studie, hvor 8 forsøgspersoner med moderat nedsat leverfunktion (primært klassificeret som Child-Pugh-score B grundet øgede encefalopati- og ascites-scorer) blev sammenlignet med 8 forsøgspersoner uden nedsat leverfunktion.
English: Discuss your hepatitis B therapy with your doctor.
Danish: Tal med lægen om din hepatitis B-behandling.
English: Lamivudine has been identified in breast-fed newborns/infants of treated women.
Danish: Lamivudin er påvist hos nyfødte/spædbørn, ammet af kvinder, som er i behandling.
English: Yellow, oval-shaped, tablet of dimensions 21.59 mm x 11.30 mm, debossed with the corporate logo and 776 on one side and plain on the other side.
Danish: Gul, oval tablet, 21,59 mm x 11,30 mm, med virksomhedslogo og 776 præget på den ene side og uden prægning på den anden side.
English: It is recommended that estimated CrCl be assessed in all patients prior to initiating therapy and as clinically appropriate during therapy with Delstrigo.
Danish: Det anbefales, at estimeret CrCl vurderes hos alle patienter før initiering af behandling med Delstrigo og efter klinisk behov under behandlingen.
English: canagliflozin liraglutide sitagliptin
Danish: canagliflozin liraglutid sitagliptin
English: What Delstrigo is
Danish: Hvad Delstrigo er
English: ≥ 200 cells/mm
Danish: ≥ 200 celler/mm
English: Animal studies with lamivudine showed an increase in early embryonic deaths in rabbits but not in rats (see section 5.3).
Danish: Dyreforsøg med lamivudin viste en stigning i antallet af dødsfald i det tidlige fosterstadium hos kaniner, men ikke hos rotter (se pkt.
English: Reproduction studies with orally administered doravirine have been performed in rats and rabbits at exposures approximately 9 times (rats) and 8 times (rabbits) the exposure in humans at the recommended human dose (RHD) with no effects on embryo-foetal (rats and rabbits) or pre/postnatal (rats) development.
Danish: Der er udført reproduktionsstudier med oralt administreret doravirin hos rotter og kaniner ved eksponeringer ca. 9 gange (rotter) og 8 gange (kaniner) eksponeringen hos mennesker ved den anbefalede dosis til mennesker (RHD) uden indvirkning på den embryo-føtale (rotter og kaniner) eller præ-/postnatale (rotter) udvikling.
English: The principal mode of action of 3TC-TP is inhibition of RT via DNA chain termination after incorporation of the nucleotide analogue.
Danish: Den primære virkningsmekanisme for 3TC-TP er hæmning af RT via DNA-kæde-terminering efter inkorporering af nukleotidanalogen.
English: *NRTI in DOR arm: FTC/TDF (333) or ABC/3TC (50); NRTI in DRV+r arm: FTC/TDF (335) or ABC/3TC (48) **Subjects received FTC/TDF
Danish: *NRTIer i DOR-armen: FTC/TDF (333) eller ABC/3TC (50); NRTIer i DRV+r-armen: FTC/TDF (335) eller ABC/3TC
English: Assessment of BMD should be considered for HIV-1 infected adult patients who have a history of pathologic bone fracture or other risk factors for osteoporosis or bone loss.
Danish: Det bør overvejes at vurdere BMD for hiv-1-inficerede voksne patienter med patologisk knoglefraktur i anamnesen eller andre risikofaktorer for osteoporose eller knogletab.
English: • telotristat ethyl (a medicine to treat diarrhea in people with carcinoid syndrome)
Danish: • telotristatethyl (et lægemiddel til behandling af diarré hos personer med karcinoidsyndrom)
English: No significant cross-resistance has been demonstrated between doravirine-resistant HIV-1 variants and lamivudine/emtricitabine or tenofovir or between lamivudine- or tenofovir-resistant variants and doravirine.
Danish: Der er ikke påvist signifikant krydsresistens mellem doravirin-resistente hiv-1-varianter og lamivudin/emtricitabin eller tenofovir eller mellem lamivudin- eller tenofovir-resistente varianter og doravirin.
English: The K65R substitution in HIV-1 RT selected by tenofovir is also selected in some HIV-1 infected patients treated with abacavir or didanosine.
Danish: K65R-substitutionen i hiv-1-RT, der blev selekteret for ved anvendelse af tenofovir, er også selekteret for hos nogle hiv-1-inficerede patienter, som blev behandlet med abacavir eller didanosin.
English: Cmax and AUC values were 0.30 ± 0.09 micrograms per mL and 2.29 ± 0.69 µg•hr per mL, respectively.
Danish: Cmax- og AUC-værdierne var henholdsvis 0,30 ± 0,09 µg pr. ml og 2,29 ± 0,69 µg•t pr. ml.
English: In the DRIVE-SHIFT clinical trial, no subjects developed genotypic or phenotypic resistance to DOR, 3TC, or TDF during the initial 48 weeks (immediate switch, N=447) or 24 weeks (delayed switch, N=209) of treatment with Delstrigo.
Danish: I det kliniske studie DRIVE-SHIFT var der ingen forsøgspersoner, der udviklede genotypisk eller fænotypisk resistens over for DOR, 3TC eller TDF i de første 48 uger (øjeblikkeligt skift, N=447) eller 24 uger (sent skift, N=209) under behandlingen med Delstrigo.
English: EC50 values were in the range of 0.003 to 15 microM (1 microM = 0.23 micrograms per mL).
Danish: EC50værdierne lå i intervallet 0,003 til 15 µM (1 µM = 0,23 µg pr. ml).
English: Administration of lamivudine in animal toxicity studies at high doses was not associated with any major organ toxicity.
Danish: Administration af lamivudin i høje doser i toksicitetsstudier hos dyr var ikke forbundet med større organtoksicitet.
English: Treatment naïve adult subjects
Danish: Behandlingsnaive voksne forsøgspersoner
English: In vitro studies have determined that neither tenofovir disoproxil nor tenofovir are substrates for the CYP450 enzymes.
Danish: I in vitro-studier er det fastlagt, at hverken tenofovirdisoproxil eller tenofovir er substrater for CYPenzymerne.
English: In a study comparing 8 subjects with severe renal impairment to 8 subjects without renal impairment, the single dose exposure of doravirine was 31 % higher in subjects with severe renal impairment.
Danish: I et studie, hvor 8 forsøgspersoner med svært nedsat nyrefunktion blev sammenlignet med 8 forsøgspersoner uden nedsat nyrefunktion, var enkeltdosiseksponeringen for doravirin 31% højere hos forsøgspersoner med svært nedsat nyrefunktion.
English: Discontinued study due to AE or Death
Danish: Udtrådt af studie på grund af bivirkning eller død
English: 2031 BN Haarlem NETHERLANDS
Danish: 2031 BN Haarlem Holland
English: buprenorphine naloxone
Danish: buprenorphin naloxon
English: Limited data are available for patients whose virus expressed a Y115F substitution (n = 3), Q151M substitution (n = 2), or T69 insertion (n = 4) in HIV-1 RT, all of whom had a reduced response in clinical trials.
Danish: Der foreligger begrænsede data om patienter, hvis virus udtrykte en Y115F-substitution (n=3), Q151M-substitution (n=2) eller T69insertion (n=4) i hiv-1-RT, og disse havde alle et reduceret respons i kliniske studier.
English: • dabrafenib (a medicine to treat skin cancer)
Danish: • dabrafenib (et lægemiddel til behandling af hudkræft)
English: Pharmacokinetic parameters were not altered by diminishing hepatic function.
Danish: Der skete ingen ændring i de farmakokinetiske parametre med aftagende leverfunktion.
English: Co-administration with the moderate CYP3A inducer rifabutin decreased doravirine concentrations (see Table 1).
Danish: Administration sammen med den moderate CYP3A-induktor rifabutin nedsatte koncentrationen af doravirin (se tabel 1).
English: Lamivudine is a nucleoside analogue.
Danish: Lamivudin er en nukleosidanalog.
English: The efficacy of switching from a baseline regimen consisting of two nucleoside reverse transcriptase inhibitors in combination with a ritonavir- or cobicistat-boosted PI, or cobicistat-boosted elvitegravir, or an NNRTI to Delstrigo was evaluated in a randomized, open-label trial (DRIVE-SHIFT), in virologically suppressed HIV-1 infected adults.
Danish: Virkningen af skiftet fra et baseline-regime bestående af to nukleosid revers transkriptasehæmmere i kombination med en ritonavir- eller cobicistat-boostet PI, eller cobicistat-boostet elvitegravir, eller en NNRTI til Delstrigo blev evalueret i et randomiseret, åbent studie (DRIVE-SHIFT) hos virologisk supprimerede hiv-1-inficerede voksne.
English: • enlarged liver or fatty liver, yellow skin or eyes, pain in the belly (abdomen) caused by inflammation of the liver
Danish: • forstørret lever eller fedtlever, gul hud eller gule øjne, ondt i maven (abdomen) forårsaget af leverbetændelse
English: ombitasvir/paritaprevir/ ritonavir and dasabuvir +/ritonavir
Danish: ombitasvir/ paritaprevir/ritonavir og dasabuvir +/- ritonavir
English: Film-coated tablets 30 film-coated tablets 90 (3 bottles of 30) film-coated tablets
Danish: Filmovertrukne tabletter 30 filmovertrukne tabletter 90 (3 flasker a 30) filmovertrukne tabletter
English: • if you are taking any of the following medicines: - carbamazepine, oxcarbazepine, phenobarbital, phenytoin (medicines for seizure) - rifampicin, rifapentine (medicines for tuberculosis) - St. John's wort (Hypericum perforatum, a herbal remedy used for depression and anxiety) or products that contain it - mitotane (a medicine to treat cancer) - enzalutamide (a medicine to treat prostate cancer) - lumacaftor (a medicine to treat cystic fibrosis)
Danish: • hvis du tager et eller flere af følgende lægemidler: carbamazepin, oxcarbazepin, phenobarbital, phenytoin (lægemidler mod krampeanfald) rifampicin, rifapentin (lægemidler mod tuberkulose) perikon (Hypericum perforatum, et naturlægemiddel mod depression og angst), eller lægemidler, der indeholder perikon mitotan (et lægemiddel til behandling af kræft) enzalutamid (et lægemiddel til behandling af prostatakræft) lumacaftor (et lægemiddel til behandling af cystisk fibrose).
English: Other substitutions yielded a fold change of 5-10 (G190S (5.7); K103N/P225H (7.9), V108I/Y181C (6.9), Y181V (5.1)).
Danish: Andre substitutioner gav en 5-10 gange ændring (G190S (5,7), K103N/P225H (7,9), V108I/Y181C (6,9), Y181V (5,1)).
English: Cases of acute renal failure after initiation of high-dose or multiple NSAIDs have been reported in HIV-infected patients with risk factors for renal dysfunction who appeared stable on tenofovir disoproxil.
Danish: Tilfælde af akut nyresvigt efter initiering af behandling med høje doser af eller flere NSAID er blevet rapporteret hos hiv-inficerede patienter med risikofaktorer for dysfunktion af nyrerne, som forekom stabile på tenofovirdisoproxil.
English: Exclusionary NNRTI substitutions were those listed above (DRIVE-FORWARD and DRIVE-AHEAD), with the exception of substitutions RT K103N, G190A and Y181C (accepted in DRIVE-SHIFT).
Danish: NNRTI-substitutionerne var udelukkende de ovenfor nævnte (DRIVE-FORWARD og DRIVE-AHEAD), med undtagelse af RTsubstitutionerne K103N, G190A og Y181C (accepteret i DRIVE-SHIFT).
English: • decreased levels of magnesium
Danish: • nedsat indhold af magnesium
English: Virologically suppressed adult subjects
Danish: Virologisk supprimerede voksne forsøgspersoner
English: No clinically relevant pharmacokinetic differences have been identified between men and women for doravirine, lamivudine, and tenofovir.
Danish: Ingen klinisk relevante farmakokinetiske forskelle mellem mænd og kvinder er identificeret for doravirin, lamivudin og tenofovir.
English: Blood and lymphatic systems disorders Uncommon neutropenia*, anaemia*, thrombocytopenia*
Danish: Blod og lymfesystem Ikke almindelig neutropeni*, anæmi*, trombocytopeni*
English: Some examples include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs (see section 4.4).
Danish: Nogle eksempler omfatter, men er ikke begrænset til, aciclovir, cidofovir, ganciclovir, valaciclovir, valganciclovir, aminoglycosider (f.eks. gentamicin) og høje doser af eller flere NSAID (se pkt.
English: ABC=abacavir; FTC=emtricitabine; DRV=darunavir; r=ritonavir
Danish: **Forsøgspersonerne fik FTC/TDF ABC= abacavir; FTC= emtricitabin; DRV=darunavir; r=ritonavir
English: Single dose lamivudine oral solution 300 mg lamivudine
Danish: Enkeltdosis lamivudin oral opløsning 300 mg lamivudin
English: The muscle pain, muscle weakness and decreases in potassium or phosphate in the blood may occur due to damage to kidney tubule cells.
Danish: Muskelsmerter, muskelsvaghed og nedsat indhold af kalium eller fosfat i blodet kan forekomme på grund af beskadigede nyrerørsceller.
English: Laboratory strains of HIV-1 harbouring the common NNRTI-associated mutations K103N, Y181C, or K103N/Y181C substitutions in RT exhibit less than a 3-fold decrease in susceptibility to doravirine compared to wild-type virus when evaluated in the presence of 100 % normal human serum.
Danish: Laboratoriestammer af hiv-1 med de almindelige NNRTI-associerede mutationer K103N, Y181C eller K103N/Y181C-substitutioner i RT har en mindre end 3 gange reduktion i følsomhed over for doravirin sammenlignet med vildtype-virus ved vurdering under tilstedeværelsen af 100% normalt humant serum.
English: Because a negligible amount of lamivudine was removed via (4-hour) haemodialysis, continuous ambulatory peritoneal dialysis, and automated peritoneal dialysis, it is not known if continuous haemodialysis would provide clinical benefit in a lamivudine overdose event.
Danish: Da det var en ubetydelig mængde lamivudin, der blev fjernet via hæmodialyse (over 4 timer), kontinuerlig ambulant peritonealdialyse og automatiseret peritonealdialyse, er det ukendt, om kontinuerlig hæmodialyse vil være klinisk til gavn i tilfælde af overdosering med lamivudin.
English: In clinical trials
Danish: I kliniske studier
English: Available pharmacodynamic/toxicological data in animals have shown excretion of doravirine in milk (see section 5.3).
Danish: De tilgængelige farmakodynamiske/toksikologiske data fra dyreforsøg viser, at doravirin udskilles i mælk (se pkt.
English: • thioridazine (a medicine to treat psychiatric conditions such as schizophrenia)
Danish: • thioridazin (et lægemiddel til behandling af psykiske lidelser såsom skizofreni).
English: • if you are allergic to doravirine, lamivudine or tenofovir disoproxil or any of the other ingredients of this medicine listed in section 6.
Danish: • hvis du er allergisk over for doravirin, lamivudin eller tenofovirdisoproxil eller et af de øvrige indholdsstoffer i Delstrigo (angivet i punkt 6).
English: • rifabutin (a medicine to treat some bacterial infections such as tuberculosis)
Danish: • rifabutin (et lægemiddel til behandling af visse bakterieinfektioner, f.eks. tuberkulose)
English: Tenofovir disoproxil is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate.
Danish: Tenofovirdisoproxil er en acyklisk nukleosid-fosfonatdiester-analog af adenosinmonofosfat.
English: Ask your pharmacist how to throw away medicines you no longer use.
Danish: • Spørg apotekspersonalet, hvordan du skal bortskaffe medicinrester.
English: • feeling weak, general feeling of being unwell
Danish: • svaghedsfølelse, generel følelse af ubehag.
English: In the DRIVE-SHIFT trial, an immediate switch to Delstrigo was demonstrated to be non-inferior at Week 48 compared to continuation of the baseline regimen at Week 24 as assessed by the proportion of subjects with HIV-1 RNA < 40 copies/mL.
Danish: I DRIVE-SHIFT-studiet blev øjeblikkeligt skift til Delstrigo påvist at være non-inferiørt ved uge 48 i forhold til at fortsætte på baseline-regimet ved uge 24, som det blev vurderet hos den del af forsøgspersonerne, der havde hiv-1 RNA < 40 kopier/ml.
English: See also the list in section “Other Medicines and Delstrigo”.
Danish: Se også listen under punktet “Brug af anden medicin sammen med Delstrigo”.
English: Delstrigo is indicated for the treatment of adults infected with HIV-1 without past or present evidence of resistance to the NNRTI class, lamivudine, or tenofovir (see sections 4.4 and 5.1).
Danish: Delstrigo er indiceret til behandling af hiv-1-inficerede voksne uden tidligere eller nuværende tegn på resistens over for NNRTI-klassen, lamivudin eller tenofovir (se pkt.
English: However, no dose adjustment is needed when doravirine is co-administered with CYP3A inhibitors.
Danish: Dosisjustering er dog ikke nødvendig, når doravirin administreres sammen med CYP3A-hæmmere.
English: In some subjects treated with zidovudine plus didanosine, isolates resistant to multiple RT inhibitors, including lamivudine, have emerged.
Danish: Hos nogle forsøgspersoner, som er blevet behandlet med zidovudin plus didanosin, er der opstået isolater, som er resistente over for flere RT-hæmmere, herunder lamivudin.
English: 3, 84 % were male, 27 % were non-white, 4 % had hepatitis B and/or C virus co-infection, 10 % had a history of AIDS, 20 % had HIV-1 RNA greater than 100,000 copies per mL, 13 % received ABC/3TC and 87 % received FTC/TDF; these characteristics were similar between treatment groups.
Danish: 3, 84% var mænd, 27% var ikke kaukasiere, 4% var samtidigt inficeret med hepatitis B- og/eller C-virus, 10% havde aids i anamnesen, 20% havde hiv-1-RNA større end 100.000 kopier pr. ml, 13% fik ABC/3TC, og 87% fik FTC/TDF; disse karakteristika var sammenlignelige mellem behandlingsgrupperne.
English: Psychiatric disorders Common abnormal dreams, insomnia
Danish: Psykiske forstyrrelser Almindelig unormale drømme, insomni
English: Excretion of unchanged medicinal product via urinary excretion is minor.
Danish: Uomdannet lægemiddel udskilles i mindre grad via urinen.
English: The antiviral activity of lamivudine against HIV-1 was assessed in a number of cell lines including monocytes and peripheral blood mononuclear cells (PBMCs) using standard susceptibility assays.
Danish: Lamivudins antivirale aktivitet mod hiv-1 blev vurderet i en række cellelinjer, herunder monocytter og mononukleære celler fra perifert blod (PBMC), ved brug af standard-følsomhedsanalyser.
English: Bone problems include bone pain, and bone softening or thinning (which may lead to fractures).
Danish: Knogleproblemer omfatter knoglesmerter og blødere eller tyndere knogler (hvilket kan føre til knoglebrud).
English: Antiandrogens enzalutamide
Danish: Antiandrogener enzalutamid
English: Anticonvulsants carbamazepine oxcarbazepine phenobarbital phenytoin
Danish: Antikonvulsiva carbamazepin oxcarbazepin phenobarbital phenytoin
English: • modafinil (a medicine to treat excessive sleepiness)
Danish: • modafinil (et lægemiddel til behandling af overdreven søvnighed)
English: See list under “Do not take Delstrigo” section.
Danish: Se listen under punktet “Tag ikke Delstrigo”.
English: Tenofovir disoproxil was mutagenic in the in vitro mouse lymphoma assay and negative in an in vitro bacterial mutagenicity test (Ames test).
Danish: Tenofovirdisoproxil var mutagent i in vitro-muselymfomanalysen og negativt i en in vitro-analyse af bakteriel mutagenicitet (Ames' test).
English: Lamivudine-resistant variants of HIV-1 have been selected in cell culture and in subjects treated with lamivudine.
Danish: Lamivudin-resistente varianter af hiv-1 er blevet fundet i cellekultur og hos forsøgspersoner, der blev behandlet med lamivudin.
English: If you forget to take Delstrigo
Danish: Hvis du har glemt at tage Delstrigo
English: Common NNRTI resistant mutations (K103N, Y181C) were not selected in the in vitro study.
Danish: Der blev ikke selekteret for almindelige NNRTI-resistente mutationer (K103N, Y181C) i in vitro-studiet.
English: The pharmacokinetics of tenofovir following a 245 mg dose of tenofovir disoproxil have been studied in healthy subjects with moderate to severe hepatic impairment.
Danish: Tenofovirs farmakokinetik efter en 245 mg dosis tenofovirdisoproxil er blevet undersøgt hos raske forsøgspersoner med moderat til svært nedsat leverfunktion.
English: Persistent or worsening bone pain, pain in extremities, fractures, and/or muscular pain or weakness may be manifestations of proximal renal tubulopathy and should prompt an evaluation of renal function in at risk patients.
Danish: Persisterende eller tiltagende knoglesmerter, ekstremitetssmerter, frakturer og/eller muskelsmerter eller -svaghed kan være tegn på proksimal renal tubulopati og bør foranledige en vurdering af nyrefunktionen hos patienter i risikogruppen.
English: HIV-1 isolates selected by tenofovir expressed a K65R substitution in HIV-1 RT and showed a 2-4 fold reduction in susceptibility to tenofovir.
Danish: Hiv-1-isolater, der blev selekteret for ved anvendelse af tenofovir, udtrykte en K65R-substitution i hiv-1-RT og viste en 2-4 gange reduktion i følsomhed over for tenofovir.
English: Common: may affect up to 1 in 10 people:
Danish: Almindelig: kan forekomme hos op til 1 ud af 10 personer:
English: Uncommon constipation, abdominal discomfort
Danish: Ikke almindelig obstipation, abdominalt ubehag
English: Pharmacokinetic parameters of tenofovir were determined following administration of a single dose of tenofovir disoproxil 245 mg to 40 non-HIV infected adult subjects with varying degrees of renal impairment defined according to baseline CrCl (normal renal function when CrCl > 80 mL/min; mild with CrCl = 50-79 mL/min; moderate with CrCl = 30-49 mL/min and severe with CrCl = 10-29 mL/min).
Danish: Farmakokinetiske parametre for tenofovir blev bestemt efter administration af en enkelt dosis tenofovirdisoproxil 245 mg til 40 voksne forsøgspersoner, der ikke var inficeret med hiv og med forskellige grader af nedsat nyrefunktion, som var defineret i henhold til CrCl ved baseline (normal nyrefunktion, når CrCl > 80 ml/min, let nedsat ved CrCl = 50-79 ml/min, moderat nedsat ved CrCl = 30-49 ml/min og svært nedsat ved CrCl = 10-29 ml/min).
English: In DRIVE-AHEAD, a lower proportion of subjects who discontinued due to an adverse event by Week 48 was seen for the Delstrigo group (3.0 %) compared with the EFV/FTC/TDF group (6.6 %).
Danish: I DRIVE-AHEAD blev der set en lavere andel af forsøgspersoner, der var udtrådt af studiet på grund af en bivirkning ved uge 48, i Delstrigo-gruppen (3,0%) sammenlignet med EFV/FTC/TDF-gruppen
English: The median EC50 values of lamivudine were 60 nM (range: 20 to 70 nM), 35 nM (range: 30 to 40 nM), 30 nM (range: 20 to 90 nM), 20 nM (range: 3 to 40 nM), 30 nM (range: 1 to 60 nM), 30 nM (range: 20 to 70 nM), 30 nM (range: 3 to 70 nM), and 30 nM (range: 20 to 90 nM) against HIV-1 clades A-G and group O viruses (n = 3 except n = 2 for clade B) respectively.
Danish: Lamivudins median-EC50-værdier var 60 nM (interval: 20 til 70 nM), 35 nM (interval: 30 til 40 nM), 30 nM (interval: 20 til 90 nM), 20 nM (interval: 3 til 40 nM), 30 nM (interval: 1 til 60 nM), 30 nM (interval: 20 til 70 nM), 30 nM (interval: 3 til 70 nM) og 30 nM (interval: 20 til 90 nM) mod henholdsvis hiv-1 clade A-G- og gruppe O-vira (n = 3, med undtagelse af n = 2 for clade B).