FrancophonIA/ELRC3.0 huggingface dataset:
English: a Whenever possible, the BO segment selected for treatment should include normal tissue margins of a few millimetres at the proximal and distal ends.
Bulgarian: Kadar je mogoče, mora segment BP, izbran za zdravljenje, vključevati običajne robove tkiv nekaj milimetrov na proksimalnih in distalnih koncih.
English: Patients randomised to the OM only group received orally omeprazole 20 mg BID for the duration of the study.
Bulgarian: Bolniki, ki so bili naključno razvrščeni v skupino, ki je dobivala samo OM, so dobili 20 mg omeprazola peroralno dvakrat na dan v času raziskave.
English: Porfimer sodium is cleared slowly from the body, with a mean CLT of 0.859 ml/h/kg (C.V. 53%) in patients.
Bulgarian: Porfimer-natrij se pri bolnikih počasi izčisti iz telesa, pri čemer je CLT 0,859 ml/h/kg (C.V. 53%).
English: The laser light application will induce difficulties with swallowing (pain, nausea and vomiting).
Bulgarian: s hrano in pijačo Uporaba laserske svetlobe povzroči težave pri požiranju (bolečino, slabost in bruhanje).
English: Patients may receive a second course of PDT a minimum of 90 days after the initial therapy; up to three courses of PDT (each injection separated by a minimum of 90 days) should be given to a previously treated segment which still shows HGD or to a new segment if the initial Barrett's segment was >7 cm in length.
Bulgarian: Bolniki lahko dobijo drugo epizodo PDT najmanj 90 dni po začetnem zdravljenju; predhodno zdravljeni del, ki še vedno kaže HGD, ali novi del lahko prejme do tri epizode PDT (vsako injekcijo posebej čez najmanj 90 dni), če je bila dolžina začetnega segmenta Barrettovega požiralnika >7 cm. Tako preostali kot dodatni segmenti, se lahko zdravijo
English: The first laser light session occurred 40-50 hours after injection and a second session, if indicated, occurred 96-120 hours after injection.
Bulgarian: Prvo zdravljenje z lasersko svetlobo je potekalo 40-50 ur po injiciranju, drugo, če je bilo potrebno, pa 96-120 ur po injiciranju.
English: PhotoBarr should not be used in children and adolescents below 18 years of age, due to lack of experience.
Bulgarian: Pri otrocih in mladostnikih, mlajših od 18 let, se zdravilo PhotoBarr zaradi pomanjkanja izkušenj ne priporoča.
English: Both residual and additional segments may be treated in the same light session(s) if the total length of the segments treated with the balloon/diffuser combination is not greater than 7 cm.
Bulgarian: s svetlobo v času istih obiskov, če celotna dolžina segmentov, zdravljenih s kombinacijo balona/difuzorja, ni večja od 7 cm.
English: Avoid direct exposure to bright indoor lights, including dental lamps, operating room lamps, unshaded light bulbs at close proximity or neon lights.
Bulgarian: svetlobi vključno z zobozdravstvenimi svetilkami, lučmi v operacijskih dvoranah, nezasenčenimi žarnicami v neposredni bližini ali neonskimi
English: PhotoBarr should not be used during pregnancy unless clearly necessary.
Bulgarian: PhotoBarra ne smete uporabljati med nosečnostjo, razen v nujnih primerih.
English: The second stage of therapy is illumination with laser light 40-50 hours following injection with PhotoBarr.
Bulgarian: Druga stopnja zdravljenja je osvetlitev z lasersko svetlobo 40-50 ur po injiciranju
English: Instructions for reconstitution
Bulgarian: Navodilo za pripravo zdravila
English: If you go out during daylight hours (even on cloudy days and while travelling in a vehicle), you should take the following precautions:
Bulgarian: Če greste podnevi na prosto (tudi v oblačnem vremenu in med vožnjo z avtomobilom), se zaščitite, kot sledi: zakrijte si čim večji del kože tako, da nosite
English: Read the package leaflet before use.
Bulgarian: Pred uporabo natančno preberite navodilo!
English: With light activation, porfimer sodium was mutagenic in some in-vitro tests.
Bulgarian: svetlobe je bil porfimer-natrij mutagen v nekaterih in vitro preskusih.
English: In rats porfimer sodium passed into breast milk.
Bulgarian: Pri podganah je porfimer-natrij prehajal v materino mleko.
English: Pinnacle Biologics B.V., p/a Trust Company Amsterdam B.V., Crystal Tower 21st Floor, Orlyplein 10, 1043 DP Amsterdam, The Netherlands
Bulgarian: Pinnacle Biologics B.V., p/a Trust Company Amsterdam B.V., Crystal Tower 21st Floor, Orlyplein
English: Both the medicine and laser light are necessary for the therapy to work.
Bulgarian: Za uspešnost zdravljenja sta potrebna tako zdravilo kot laserska svetloba.
English: Based on evidence for a primarily hepatic/biliary elimination of photoactive substances, severity of phototoxic reactions and duration of the period of photosensitivity in patients with any grade of hepatic impairment may be increased.
Bulgarian: Na osnovi dokazov za v prvi vrsti jetrno/žolčno izločanje fotoaktivnih spojin lahko zaključimo, da bosta resnost fototoksičnih reakcij in trajanje občutljivosti za svetlobo pri bolnikih
English: PhotoBarr is for single use only and any unused solution should be discarded.
Bulgarian: PhotoBarr je namenjen za enkratno uporabo; neuporabljeno raztopino zavrzite.
English: Very common: Oesophageal stenosis acquired*, vomiting*, dysphagia, constipation,
Bulgarian: Zelo pogoste: Pridobljena ezofagealna stenoza*, bruhanje*, disfagija, zaprtje, slabost*.
English: Of the serious adverse events (SAEs) in the PhotoBarr PDT + OM group, 44 (23.1%) were considered associated with the treatment.
Bulgarian: Od hudih neželenih učinkov (HNU) v skupini bolnikov, ki so dobivali PhotoBarr PDT + OM, se je štelo, da jih je 44 (23,1%) nastalo kot posledica zdravljenja.
English: Women of childbearing age should take adequate contraceptive precautions whilst and up to 90 days after receiving PhotoBarr.
Bulgarian: Ženske v rodni dobi naj jemljejo ustrezna kontracepcijska sredstva med in do 90 dni po uporabi
English: PhotoBarr 75 mg vial should be reconstituted with 31.8 ml of 5% glucose solution for injection, resulting in a final porfimer sodium concentration of 2.5 mg/ml in the solution for injection.
Bulgarian: 75 mg-vialo PhotoBarra je treba pripraviti z 31,8 ml 5% raztopine glukoze za injiciranje, katere rezultat je končna koncentracija porfimer-natrija v raztopini za injiciranje 2,5 mg/ml.
English: The survival curves indicated that, by the end of the entire follow-up period, patients in the PhotoBarr PDT + OM group had a 83% chance of being cancer-free as compared to a 53% chance for patients in the OM only group.
Bulgarian: Krivulje preživetja so pokazale, da so imeli do konca celotnega spremljevalnega obdobja bolniki v skupini, ki je dobivala PhotoBarr PDT + OM, 83% možnost, da ne zbolijo za rakom, v primerjavi
English: Bronchitis, nail fungal infection, sinusitis, skin infection
Bulgarian: Bronhitis, glivične okužbe nohtov, sinuzitis, infekcije kože
English: − Any unused product or waste material should be disposed of in accordance with local requirements.
Bulgarian: − Neuporabljeno zdravilo ali odpadni material zavrzite v skladu z lokalnimi predpisi.
English: Compounds that quench active oxygen species or scavenge radicals, such as dimethyl sulphoxide, b-carotene, ethanol, formate and mannitol would be expected to decrease PDT activity.
Bulgarian: Od snovi, ki udušijo aktivne vrste kisika, ali sproščajo radikale, kot so dimetilsulfoksid, b-karoten, etanol, format in manitol, bi pričakovali, da zmanjšajo delovanje PDT.
English: If some photosensitivity reaction occurs with the limited skin test, the patient should continue exercising precautions for another 2 weeks before retesting.
Bulgarian: Če se pri omejenem kožnem preskusu pojavi kaka fotosenzitivna reakcija, mora biti bolnik previden še naslednja 2
English: Eligible patients for this study were to have biopsy-proven HGD in Barrett's oesophagus (BO).
Bulgarian: Bolniki, primerni za to raziskavo, so morali imeti z biopsijo potrjeno HGD v Barrettovem požiralniku (BP).
English: - Hypersensitivity to the active substance, other porphyrins or to any of the excipients.
Bulgarian: - Preobčutljivost za zdravilno učinkovino, druge porfirine ali katero koli pomožno snov.
English: PhotoBarr is used to remove high-grade dysplasia (cells with atypical changes that increase the risk of developing cancer) in patients with Barrett's oesophagus (gullet).
Bulgarian: PhotoBarr se uporablja za odpravo displazije (celice z netipičnimi spremembami, ki povečujejo tveganje za razvoj raka) visoke stopnje pri bolnikih z Barrettovim požiralnikom.
English: There are no clinical data on exposed pregnancies available for porfimer sodium.
Bulgarian: Kliničnih podatkov o izpostavljenosti nosečnic porfimer-natriju ni na voljo.
English: The majority of the SAEs experienced were gastrointestinal disorders (8% - 11 patients), specifically nausea (3% - 4 patients), vomiting (3% - 4 patients) and upper abdominal pain (2% - 2 patients).
Bulgarian: Večina HNU so bile prebavne motnje (8% - 11 bolnikov), posebno slabost (3% - 4 bolniki), bruhanje (3% - 4 bolniki)
English: Skin and eye contact should be avoided due to the potential for photosensitivity reactions upon exposure to light; use of rubber gloves and eye protection is recommended.
Bulgarian: s kožo in očmi, ker lahko pri izpostavljenosti svetlobi izzove preobčutljivostne reakcije; priporočljiva je uporaba gumijastih rokavic
English: The frequency and nature of the photosensitivity reactions experienced in this study are unlike the documented incidence seen in previous clinical studies in cancer patients (approx. 20%) or the spontaneously reported incidence from commercial use of PhotoBarr (< 20%).
Bulgarian: Pogostost in vrsta preobčutljivostnih reakcij na svetlobo, ki so nastale v tej raziskavi, niso take kot so pojavi, opaženi v prejšnjih kliničnih raziskavah pri rakavih bolnikih (približno 20%), ali pojavi, o katerih
English: You may receive a second laser light treatment 96-120 hours after the initial injection of PhotoBarr.
Bulgarian: tudi drugo zdravljenje z lasersko svetlobo 96-120 ur po začetnem vbrizganem odmerku PhotoBarra.
English: Photodynamic therapy with PhotoBarr is a two-stage process requiring administration of both medicinal product and light.
Bulgarian: s PhotoBarrom je dvostopenjski proces, ki zahteva uporabo tako zravila kot svetlobe.
English: Photodynamic therapy with PhotoBarr has exclusively been studied in patients not suffering from severe medical conditions, such as congestive heart failure of advanced stage or serious pulmonary conditions that might impair the eligibility of patients for surgical procedures.
Bulgarian: smo preučevali izključno pri bolnikih, ki ne trpijo zaradi hudih bolezenskih stanj, kot so kongestivna srčna odpoved v napredovali fazi ali hude pljučne bolezni, ki bi lahko vplivale na
English: A dark red to reddish brown lyophilised powder or cake.
Bulgarian: Temno rdeč do rdečkastorjav liofiliziran prašek ali pogača.
English: Fibre optic diffuser/balloon combinationa
Bulgarian: Preglednica 1. Kombinacija difuzorja z optičnimi vlakni/balonaa
English: 75 mg powder in a vial (glass type I, 40 ml capacity) with a grey butyl stopper.
Bulgarian: 75 mg praška v viali (steklo hidrolitske skupine I, prostornina 40 ml ) s sivim butilnim zamaškom.
English: Treatment time (sec)
Bulgarian: Čas zdravljenja (sek)
English: In the clinical studies with PhotoBarr, follow-up surveillance was done every three months, or every six months after four consecutive biopsy results had shown no more high-grade dysplasia (see section 5.1).
Bulgarian: spremljevalni kontrolni pregled vsake tri mesece ali celo vsakih šest mesecev po tem, ko rezultati štirih zaporednih biopsij niso več pokazali visoke stopnje displazije (glejte poglavje 5.1).
English: The effects of an overdose on the duration of photosensitivity are unknown.
Bulgarian: Ni znanih učinkov prevelikega odmerjanja na trajanje občutljivosti na svetlobo.
English: One course of PDT consists of one injection of PhotoBarr plus one or two laser light applications.
Bulgarian: En ciklus PDT sestoji iz enega injiciranja PhotoBarra ter ene ali dveh aplikacij laserske svetlobe.
English: They consist mainly of sunburn-like reactions, mild redness on exposed skin, usually the face and hands.
Bulgarian: Predstavljajo jih predvsem reakcije, podobne sončnim opeklinam, blaga rdečina na izpostavljeni koži, navadno na obrazu
English: Laser light
Bulgarian: Uporaba laserske svetlobe
English: 6.6 Special precautions for disposal and other handling
Bulgarian: 6.6 Posebni varnostni ukrepi za odstranjevanje in ravnanje z zdravilom
English: Conventional UV (ultraviolet) sunscreens are of no value in protecting against photosensitivity reactions because photoactivation is caused by visible light.
Bulgarian: so brez učinka pri zaščiti pred fotosenzitivnimi reakcijami, ker fotoaktivacijo povzroča vidna svetloba.
English: The recommended 2 mg/kg dose, instead of the recommended single administration, was given twice two days apart (10 patients) and three times within two weeks (1 patient), without any notable adverse reactions being reported.
Bulgarian: Priporočeni odmerek zdravila 2 mg/kg, namesto priporočenega enkratnega odmerka, dan dvakrat (10 bolnikom) v razmaku dveh dni, in trikrat 2 mg/kg (1 bolniku) v času dveh tednov, so bolniki prenašali brez opaznih neželenih učinkov.
English: - Oesophageal or gastric varices or patients with oesophageal ulcers >1 cm in diameter.
Bulgarian: - Varice požiralnika ali želodca ali bolniki z razjedami požiralnika premera >1 cm.
English: Table 3 lists appropriate fibre optic power outputs and treatment times using a light intensity of 400 mW/cm.
Bulgarian: Preglednici 3 so naštete ustrezne izhodne moči difuzorjev z optičnimi vlakni ter časi zdravljenja pri uporabljeni jakosti svetlobe 400 mW/cm.
English: If eating or drinking becomes impossible or if you keep vomiting, please return to the clinical for medical attention.
Bulgarian: Če ne morete jesti ali piti, ali če se bruhanje ponavlja, pojdite nazaj na kliniko, kjer vam bodo nudili
English: How does photodynamic therapy (PDT) work?
Bulgarian: Fotodinamično zdravljenje (PDT, photodynamic therapy)
English: OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF
Bulgarian: ZDRAVIL ALI IZ NJIH NASTALIH ODPADNIH SNOVI, KADAR SO POTREBNI
English: Very common side effects fever photosensitivity reactions (see section 3) vomiting, nausea tightening of the gullet (oesophagus), difficulty in swallowing that may cause pain constipation, dehydration
Bulgarian: Zelo pogosti neželeni učinki vročina, fotosenzitivni odzivi (glejte poglavje 3), bruhanje, slabost, zoženje požiralnika, težave pri požiranju, ki je lahko boleče, zaprtje, dehidracija.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton - 15 mg
Bulgarian: PODATKI NA ZUNANJI OVOJNINI Karton - 15 mg
English: Since PhotoBarr is activated by the red part of light, sunscreens for UV (ultraviolet) light will not protect you against photosensitivity reactions.
Bulgarian: svetlobe, vas zaščitni faktorji, ki ščitijo pred UV (ultravijolično) svetlobo, ne bodo obvarovali pred fotosenzitivnimi reakcijami.
English: Women of child-bearing potential should use effective contraception before, during and for at least 90 days after treatment.
Bulgarian: Ženske v rodni dobi naj uporabljajo učinkovito kontracepcijo pred zdravljenjem, med njim in najmanj
English: Treatment Time (min:sec)
Bulgarian: Čas zdravljenja (min:sek)
English: In vitro binding of porfimer sodium to human serum protein is around 90% and independent of concentration between 20 and 100 μg/ml.
Bulgarian: In vitro vezava porfimer-natrija na človeške beljakovine v serumu je približno 90% in ni odvisna od
English: Patients should be advised to consult their ophthalmologist if they notice any vision changes after treatment with PhotoBarr PDT.
Bulgarian: Bolnikom je treba svetovati, da se posvetujejo z oftalmologom, če opazijo kakršne koli spremembe
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton - 75 mg
Bulgarian: PODATKI NA ZUNANJI OVOJNINI Karton - 75 mg
English: After reconstitution, each ml solution contains 2.5 mg porfimer sodium.
Bulgarian: Po pripravi vsebuje vsak ml raztopine 2,5 mg
English: − Photosensitivity can only be prevented by avoiding exposure to the sun for 90 days after receiving the PhotoBarr injection
Bulgarian: − Fotosenzitivne reakcije se lahko preprečijo samo, če se izognete izpostavljenosti kože in oči svetlobi v obdobju 90 dni po injekciji PhotoBarra.
English: No formal interaction studies have been performed with PhotoBarr investigating pharmacokinetic interactions with other medicinal products.
Bulgarian: s PhotoBarrom o medsebojnem delovanju, ki bi preučevale farmakokinetične interakcije z drugimi zdravili.
English: It is possible that concomitant use of other photosensitising agents (e.g., tetracyclines, sulphonamides, phenothiazines, sulphonylurea hypoglycaemic agents, thiazide diuretics, griseofulvin and fluoroquinolones) could increase the photosensitivity reaction.
Bulgarian: tetraciklinov, sulfonamidov, fenotiazinov, hipoglikemičnih pripravkov sulfoniluree, tiazidnih diuretikov, grizeofulvina ter fluorokinolonov) lahko poveča fotosenzitivno reakcijo.
English: The necrotic reaction and associated inflammatory response evolve over several days.
Bulgarian: Nekrotična reakcija in z njo povezana vnetna reakcija
English: Tracheo-oesophageal fistula, Gastrointestinal necrosis Skin and subcutaneous tissue disorders
Bulgarian: Traheoezofagenalna fistula, gastrointestinalna nekroza
English: The cytotoxic actions of porfimer sodium are light and oxygen-dependent.
Bulgarian: Citotoksični učinki porfimer-natrija so blagi in odvisni od kisika.
English: If not used immediately, in-use storage time and conditions prior to use are the responsibility of the user.
Bulgarian: Če se zdravilo ne uporabi takoj, je uporabnik odgovoren za čas shranjevanja
English: Special care to ensure accurate PhotoBarr dosing and/or light dose is crucial, since miscalculation of either medicinal product or light dose may lead to a less effective treatment or cause detrimental effect to the patient.
Bulgarian: Odločilna je posebna skrb za zagotavljanje točnega odmerjanja PhotoBarra in/ali odmerka svetlobe, ker lahko napačen
English: Breastfeeding should be terminated prior to treatment.
Bulgarian: Pred začetkom zdravljenja je treba prenehati dojiti.
English: These patients may be at higher risk for the development of cardiac and pulmonary related adverse events such as heart rhythm disorders, angina pectoris, dyspnoea, cough, pleural effusion, pharyngitis, atelectasis and events like dehydration (see also section 4.8).
Bulgarian: srčnega ritma, angina pectoris, dispneja, kašelj, plevralni izliv, faringitis, atelektaza ter pojavi, kot so dehidracija (glejte tudi poglavje 4.8), večje.
English: Fibre optic power outputs and treatment times required to deliver 130 J/cm of diffuser length using the centring balloon
Bulgarian: Preglednica 2. Izhodne moči difuzorjev z optičnimi vlakni in časi zdravljenja, potrebni za dajanje 130 J/cm dolžine difuzorja z uporabo balona za centriranje
English: − Record the patient's skin type and the date of injection on the patient alert card
Bulgarian: tip kože in datum injiciranja zdravila.
English: Tell your doctor immediately:
Bulgarian: Vaš zdravnik se
English: One course of PDT consists of one injection plus one or two light applications.
Bulgarian: En ciklus PDT se sestoji iz enega injiciranja PhotoBarra ter ene ali dveh aplikacij svetlobe.
English: if any of these signs are seen, then continue to protect yourself from bright light for 2 more weeks, then repeat the skin test.
Bulgarian: Če opazite katere od teh znakov, se še naprej zaščitite pred močno svetlobo v naslednjih 2
English: In clinical trials, PhotoBarr PDT has only been tested in patients being treatment naive concerning mucosal ablative therapy.
Bulgarian: V kliničnih preskušanjih PhotoBarra je bila PDT preizkušena le pri bolnikih, ki še niso bili zdravljeni z ablativnim zdravljenjem sluznice.
English: Light doses of two to three times the recommended dose have been administered to a few patients with superficial endobronchial tumours.
Bulgarian: Odmerki (laserske) svetlobe, ki so enaki dvakratnim ali trikratnim priporočenim odmerkom, so bili uporabljeni pri maloštevilnih bolnikih
English: Posology
Bulgarian: Difuzor
English: Blood albumin decreased, blood chloride increased, blood urea increased, haematocrit decreased, haemoglobin decreased, oxygen saturation decreased,
Bulgarian: Zmanjšana vrednost krvnega albumina, zvišana vrednost klorida v krvi, zvišana vrednost sečnine v krvi, zmanjšana vrednost hematokrita, zmanjšana vrednost hemoglobina, manjša nasičenost s kisikom, manjša vrednost skupnih
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2).
Bulgarian: in na recept (glejte Dodatek I: Povzetek glavnih
English: − There are a number of potential side effects that patients should be aware of.
Bulgarian: − Bolniki morajo biti seznanjenimi z možnimi neželenimi učinki.
English: Pregnancy
Bulgarian: Nosečnost
English: Tissue damage also results from ischaemia secondary to vasoconstriction, platelet activation and aggregation and clotting.
Bulgarian: Tudi poškodba tkiva je posledica ishemije, ki nastane ob vazokonstrikciji, aktivaciji in agregaciji ter strjevanju trombocitov. Raziskave na živalih
English: In patients,the mean peak plasma concentration (Cmax) was 79.6 μg/ml (C.V. 61%, range 39-222), whereas in volunteers Cmax was 40 μg/ml and AUCinf was 2400 μg/h/ml.
Bulgarian: takoj po injiciranju 79,6 μg/ml (C.V. 61%, razpon 39-222), pri prostovoljcih pa je bil Cmax 40 μg/ml in AUCinf 2400 μg/h/ml.
English: Preclinical studies indicate that the excretion of porfimer sodium components occurs primarily via the faecal route.
Bulgarian: Predklinične študije kažejo, da se sestavine porfimer-natrija izločajo predvsem z blatom.
English: Patients were excluded from the study if there was a presence of invasive oesophageal cancer, if they had a history of cancer other than nonmelanoma skin cancer or if they had received prior PDT to the oesophagus.
Bulgarian: invazivni rak požiralnika, rak v anamnezi, razen kožnega raka, ki ni bil melanom, ali če so poprej dobili PDT v požiralnik.
English: Comparison between the survival curves of the two treatment arms using the log rank test showed a statistically significant difference between the curves of the two groups in the ITT population (p=0.0014) indicating a significant delay in the progression to cancer.
Bulgarian: skupinah z uporabo testa log rank je pokazala statistično pomembno razliko med krivuljama v obeh skupinah populacije ITT (p=0,0014),
English: Short fibre optic diffusers (< 2.5 cm) are to be used to pretreat nodules with 50 J/cm diffuser length prior to regular balloon treatment in the first laser light session or for the retreatment of "skip" areas after the first light session.
Bulgarian: se uporabljajo za predhodno zdravljenje vozličkov pri dolžini difuzorja 50 J/cm pred rednim zdravljenjem z balonom pri prvem zdravljenju z lasersko svetlobo, ali za ponovno zdravljenje »izpuščenih« področij po prvem zdravljenju z lasersko svetlobo.
English: High-grade dysplasia in Barrett's oesophagus of < 7 cm
Bulgarian: Preglednica 4. Displazija visoke stopnje v Barrettovem požiralniku < 7 cm Naprave za oddajanje
English: PDT specifically targets and destroys abnormal cells.
Bulgarian: PDT cilja in uničuje
English: Tumour cell death also occurs through ischaemic necrosis secondary to vascular occlusion that appears to be partly mediated by thromboxane A2 release.
Bulgarian: s pomočjo ishemične nekroze, ki nastane kot posledica žilne okluzije, za katero se zdi, da jo delno povzroči sproščanje tromboksana A2. Lasersko zdravljenje
English: 4.7 Effects on ability to drive and use machines
Bulgarian: Raziskave o vplivu zdravila na sposobnost vožnje in upravljanje
English: Rare:
Bulgarian: Redko:
English: Neoplasms benign, malignant and unspecified (incl cysts and polyps) Uncommon:
Bulgarian: Benigne, maligne in neopredeljene novotvorbe (vključno