FrancophonIA/ELRC3.0 huggingface dataset:
English: - A 2 to 4-fold increase in the risk of gallbladder disease requiring surgery in postmenopausal women receiving oestrogens has been reported (see section 4.8).
Croatian: - U postmenopauzalnih bolesnica koje su primale estrogene prijavljen je 2 do 4 puta veći rizik od bolesti žučnog mjehura koja zahtjeva kirurški zahvat(vidjeti dio 4.8).
English: You will only be prescribed this medicine if your symptoms seriously hinder your daily life and your doctor determines that other types of HRT are not appropriate for you.
Croatian: Vaš svakodnevni život i liječnik utvrdi da za Vas nisu prikladne druge vrste hormonskog nadomjesnog liječenja.
English: Some medicines may interfere with the effect of DUAVIVE.
Croatian: Neki lijekovi mogu utjecati na učinak lijeka DUAVIVE što može dovesti do nepravilnog krvarenja.
English: The safety and efficacy of CE/BZA have not been evaluated in patients with hepatic impairment.
Croatian: Sigurnost i djelotvornost KE/BZA nije ispitivana u bolesnica s oštećenom funkcijom jetre.
English: Use in this population is therefore not recommended (see sections 4.4 and 5.2).
Croatian: Primjena u ovoj skupini se stoga ne preporučuje (vidjeti dijelove 4.4 i 5.2).
English: - Known, past or suspected oestrogen-dependent malignant tumours (e.g., endometrial cancer).
Croatian: - Zloćudni tumori ovisni o estrogenu (primjerice, rak endometrija) - dijagnosticirani, u anamnezi ili sumnja na njih.
English: Enlargement of hepatic haemangiomas
Croatian: Povećanje hemangioma jetre
English: WHI Studies combined - Additional risk of ischaemic stroke* over 5 years use Age range (years) Incidence per 1,000 women in placebo arm over 5 years
Croatian: Kombinirana WHI ispitivanja - dodatni rizik od ishemijskog moždanog udara* tijekom 5 godina primjene Dobni raspon (godine)
English: • Signs of a blood clot, such as painful swelling and redness of the legs, sudden chest pain or difficulty in breathing.
Croatian: • Znakovi krvnog ugruška kao što su bolno oticanje i crvenilo nogu, iznenadna bol u prsnom košu ili poteškoće s disanjem.
English: Cholecystitis
Croatian: Kolecistitis
English: Should a VTE event occur or be suspected, CE/BZA should be discontinued immediately.
Croatian: Ako nastupi VTE ili se na nju sumnja, uzimanje KE/BZA treba odmah prekinuti.
English: • A heart attack - symptoms will usually include pain, including chest pain spreading to the jaw, neck and upper arm. You may feel sweaty, breathless, fatigued, nauseous and faint in addition to the pain
Croatian: • Srčani udar - simptomi obično uključuju bol, uključujući bol u prsnom košu koja se širi u čeljust, vrat i nadlaktice.
English: • Hives (urticaria)
Croatian: • Koprivnjača (utrikarija)
English: If you have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina.
Croatian: - ako imate poremećaj zgrušavanja krvi (primjerice, manjak proteina C, proteina S ili antitrombina) - ako imate ili ste nedavno imali bolest uzrokovanu krvnim ugrušcima u arterijama kao što su srčani udar, moždani udar ili angina - ako imate ili ste ikada imali bolest jetre i testovi funkcije jetre
English: • an irregular heartbeat
Croatian: • nepravilni otkucaji srca
English: • Hot flushes
Croatian: • Navale vrućine
English: A single 20 mg dose of BZA was administered to these subjects.
Croatian: Te bolesnice primile su jednokratnu dozu od 20 mg BZA.
English: Hepatic impairment The pharmacokinetics of CE/BZA have not been evaluated in women with hepatic impairment.
Croatian: Oštećenje funkcije jetre Farmakokinetika KE/BZA nije ispitivana u žena s oštećenom funkcijom jetre.
English: Detectable amounts of oestrogens have been identified in the milk of mothers receiving CE. Oestrogen administration to breast-feeding mothers has been shown to decrease the quantity and quality of the milk.
Croatian: Pokazalo se da primjena estrogena u dojilja smanjuje količinu i kvalitetu mlijeka.
English: In rabbit studies with BZA, abortion and an increased incidence of heart (ventricular septal defect) and skeletal system (ossification delays, misshapen or misaligned bones, primarily of the spine and skull) anomalies in the fetuses were present at maternally toxic dosages of  0.5 mg/kg/day (1.5 times the human exposure).
Croatian: U ispitivanjima s BZA na kunićima, pri dozama toksičnima za majku od 0,5 mg/kg na dan (1,5 puta veća izloženost nego u ljudi), zabilježeni su pobačaji i povećana incidencija anomalija srca (defekt ventrikularnog septuma) i koštanog sustava ploda (odgođeno okoštavanje, deformacija ili krivi raspored kostiju, prvenstveno kralježnice i lubanje).
English: Randomised controlled data found no increased risk of coronary artery disease in hysterectomised women using oestrogen-only therapy.
Croatian: Randomizirani kontrolirani podaci nisu pokazali povećanje rizika od koronarne arterijske bolesti u žena koje su uzimale terapiju samim estrogenom a ranije su podvrgnute histerektomiji (odstranjenju maternice).
English: In case of doubt, talk to your doctor before you take this medicine.
Croatian: Ako imate bilo kakvih dvojbi, obratite se liječniku prije nego uzmete ovaj lijek.
English: The pharmacokinetics of CE/BZA have not been evaluated in patients with renal impairment.
Croatian: Farmakokinetika KE/BZA nije bila procjenjivana u bolesnica s oštećenom funkcijom bubrega.
English: Adverse reactions reported with CE and/or bazedoxifene monotherapy
Croatian: Nuspojave prijavljene kod liječenja monoterapijom KE i/ili bazedoksifenom
English: Kidney stones may develop and cause severe pain in the mid-back region (renal colic).
Croatian: Mogu se stvoriti bubrežni kamenci i uzrokovati jaku bol u središnjem dijelu leđa (bubrežne kolike).
English: • Muscle spasms (including leg cramps)
Croatian: • Mišićni spazam (uključujući grčeve u nogama)
English: Arthralgia; leg cramps
Croatian: Artralgija; grčevi u nogama
English: Breast pain, tenderness, enlargement, discharge; leucorrhoea
Croatian: Bolovi u dojkama, osjetljivost, povećanje dojki, iscjedak; leukoreja
English: • Breast pain, breast tenderness, swollen breasts
Croatian: • Bolovi i osjetljivost u dojkama, oticanje dojki
English: Polydextrose (E1200) (contains glycerol and glucose) Maltitol liquid
Croatian: Bezbojna ovojnica hidroksietilceluloza povidon (E1201) polidekstroza (E1200) (sadrži glicerol i glukozu) maltitol, tekući poloksamer 188
English: If you have or have ever had a blood clot in a vein (thrombosis), such as in the legs (deep venous thrombosis), the lungs (pulmonary embolism) or eyes (retinal vein thrombosis).
Croatian: - ako imate, sumnjate da imate ili ste imali rak osjetljiv na estrogen, kao što je rak sluznice maternice (endometrija) - ako se nedavno imali bilo kakvo neobjašnjeno vaginalno krvarenje - ako imate prekomjerno zadebljanje sluznice maternice (hiperplazija endometrija) koje se ne liječi - ako imate ili se ikada imali krvni ugrušak u veni (tromboza), primjerice u nogama (duboka venska tromboza), plućima (plućna emobolija) ili očima (tromboza retinalne vene).
English: The effect of DUAVIVE on the risk of breast cancer is unknown.
Croatian: Učinak lijeka DUAVIVE na rizik od raka dojke nije poznat.
English: The effect of DUAVIVE on the risk of ovarian cancer is unknown.
Croatian: Učinak lijeka DUAVIVE na rizik od raka jajnika nije poznat.
English: Muscle spasms (includes leg cramps)
Croatian: Mišićni spazam (uključujuć i grčeve u nogama)
English: Common: may affect 1 in 10 people
Croatian: Česte: mogu se javiti u do 1 na 10 osoba
English: Hypromellose 2910 (3 mPa•s) (E464) Sucrose monopalmitate Ascorbic acid
Croatian: Bazedoksifen aktivna ovojnica saharoza hipromeloza 2910 (3 mPa•s) (E464) saharozamonopalmitat askorbatna kiselina
English: - Active or past history of venous thromboembolism (e.g., deep venous thrombosis,
Croatian: - Aktivna ili prijašnja venska tromboembolija (primjerice, duboka venska tromboza, plućna embolija i tromboza retinalne vene).
English: Use of oestrogen-only HRT has been associated with a slightly increased risk of having ovarian cancer diagnosed (see section 4.4).
Croatian: Primjena hormonskog nadomjesnog liječenja (HNL) koja sadrži samo estrogen povezuje se s blago povećanim rizikom od dijagnoze raka jajnika (vidjeti dio 4.4).
English: • fibroids inside your womb growth of womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
Croatian: • rast sluznice maternice izvan maternice (endometrioza) ili prekomjerni rast sluznice maternice (hiperplazija endometrija) povećani rizik od razvoja krvnih ugrušaka [vidjeti „Krvni ugrušci u venama (tromboza)“]
English: • Drowsiness
Croatian: • Pospanost
English: The use of oestrogen-only HRT has been associated with a slightly increased risk of ovarian cancer.
Croatian: Primjena hormonskog nadomjesnog liječenja (HNL) koje sadrži samo estrogen povezuje se s blago povećanim rizikom od nastanka raka jajnika.
English: Leiomyoma (uterine fibroids) or endometriosis Risk factors for thromboembolic disorders (see below) Risk factors for oestrogen-dependent tumours, e.g., 1
Croatian: leiomiom (fibroidi materice) ili endometriozu čimbenike rizika za tromboembolijske poremećaje (vidjeti ispod) čimbenike rizika za tumore ovisne o estrogenu, npr. srodstvo prvog stupnja za rak dojke hipertenziju poremećaje jetre (npr. adenom jetre) šećernu bolest s krvožilnim komplikacijama ili bez njih kolelitijazu migrenu ili (jaku) glavobolju sistemski eritemski lupus hiperplaziju endometrija u anamnezi (vidjeti ispod) epilepsiju astmu otosklerozu
English: Oral oestrogen-only*
Croatian: Peroralno primijenjen samo estrogen*
English: Each modified-release tablet contains 0.45 mg of conjugated oestrogens and bazedoxifene acetate equivalent to 20 mg bazedoxifene
Croatian: Jedna tableta s prilagođenim oslobađanjem sadrži 0,45 mg konjugiranih estrogena i 20 mg bazedoksifena u obliku bazedoksifenacetata
English: • Vaginal inflammation
Croatian: • Vaginalne gljivične infekcije (kandidijaza)
English: Little or no cytochrome P450-mediated metabolism is evident.
Croatian: Vrlo malo je ili gotovo uopće nije uočljivo metaboliziranje posredovanjem citokroma P450.
English: Each modified-release tablet contains 0.45 mg of conjugated oestrogens and bazedoxifene acetate equivalent to 20 mg bazedoxifene.
Croatian: Jedna tableta s prilagođenim oslobađanjem sadrži 0,45 mg konjugiranih estrogena i 20 mg bazedoksifena u obliku bazedoksifenacetata.
English: Adverse reactions that have been observed with CE monotherapy
Croatian: Nuspojave opažene kod monoterapije KE
English: WHI studies oestrogen only arm - additional risk of VTE over 5 years' use Age range (years) Incidence per 1,000 women in placebo arm over 5 years
Croatian: Skupina WHI ispitivanja koja je primala samo estrogen - dodatni rizik od VTE tijekom 5 godina primjene Dobni raspon (godine)
English: Endometrial hyperplasia and carcinoma
Croatian: Hiperplazija i rakendometrija
English: The effect of DUAVIVE on the risk of stroke is unknown.
Croatian: Učinak lijeka DUAVIVE na rizik od moždanog udara nije poznat.
English: Randomised controlled data found no increased risk of CAD in hysterectomised women using oestrogen-only therapy.
Croatian: Randomizirano kontrolirano ispitivanje nije pokazalo povećanje rizika od KAB u žena koje su uzimale terapiju samim estrogenom a ranije su podvrgnute histerektomiji.
English: Each tablet contains 0.45 mg of conjugated oestrogens and bazedoxifene acetate equivalent to 20 mg bazedoxifene.
Croatian: Jedna tableta sadrži 0,45 mg konjugiranih estrogena i 20 mg bazedoksifena u obliku bazedoksifenacetata.
English: • changes in the nipple
Croatian: • promjene na bradavicama
English: Hypromellose 2208 (100,000 mPa•s) (E464) Magnesium stearate
Croatian: Jezgra tablete konjugiranih estrogena laktoza hidrat celuloza, mikrokristalična celuloza, prah hipromeloza 2208 (100 000 mPa•s) (E464) magnezijev stearat kalcijev fosfat
English: The effect of CE/BZA on the risk of stroke is unknown.
Croatian: Utjecaj KE/BZA na rizik od moždanog udara nije poznat.
English: Abdominal pain Constipation; diarrhoea; nausea
Croatian: Bol u trbuhu Konstipacija; proljev; mučnina
English: Evidence suggests that taking oestrogen-only HRT possibly increases the risk of breast cancer.
Croatian: Dokazi upućuju na moguće povećanje rizika od raka dojke kod uzimanja HNL-a koji sadrži samo estrogen.
English: Frequency of occurrence of adverse reactions
Croatian: Opći poremećaji i reakcije na mjestu primjene
English: • getting older
Croatian: Starije osobe
English: • Rash
Croatian: • Osip
English: Oestrous cycles and fertility were adversely affected in all bazedoxifene-treated female groups.
Croatian: U svim skupinama u kojima su ženke primale bazedoksifen zabilježen je štetan utjecaj na estrusni ciklus i plodnost.
English: - Known, suspected, or past history of breast cancer.
Croatian: Rak dojke - dijagnosticiran, u anamnezi ili sumnja na njega.
English: Colour coating
Croatian: Učestalost nuspojava
English: Tel: + 385 1 3908 777
Croatian: Τηλ: +357 22 817690
English: The effect of CE/BZA on the risk of ovarian cancer is unknown.
Croatian: Utjecaj KE/BZA na rak jajnika nije poznat.
English: The effect of CE/BZA on the risk of breast cancer is unknown.
Croatian: Utjecaj KE/BZA na rak dojke nije poznat.
English: Ischaemic stroke
Croatian: Ishemijski moždani udar
English: Pfizer Hellas (Cyprus Branch) A.E. Τηλ: +357 22 817690
Croatian: Pfizer Croatia d.o.o. Tel: + 385 1 3908 777
English: Reporting of side effects
Croatian: Sadržaj pomoćnih tvari
English: • gallstones
Croatian: • Omaglica
English: Otosclerosis
Croatian: Valunzi
English: Skin and subcutaneous tissue
Croatian: Gustoća tkiva dojki
English: Your doctor will advise you on what to do.
Croatian: Liječnik će Vam savjetovati što da učinite.
English: Date of first authorisation: 29 March 2001.
Croatian: Datum prvog odobrenja: 29. ožujka 2001.
English: Always take this medicine exactly as your doctor has told you.
Croatian: Uvijek uzmite ovaj lijek točno onako kako Vam je to rekao Vaš liječnik.
English: Body Surface Area (m
Croatian: Površina tijela (m
English: This is important as using more than one medicine at the same time can strengthen or weaken the effect of the medicines.
Croatian: To je važno jer primjena više od jednog lijeka istodobno može pojačati ili oslabiti učinke ovih lijekova.
English: Date of latest renewal: 24 April 2006.
Croatian: Datum posljednje obnove odobrenja: 24. travnja 2006.
English: The doctor will prescribe a suitable dose for you.
Croatian: Liječnik će Vam propisati prikladnu dozu.
English: Targretin with food and drink
Croatian: Targretin s hranom i pićem
English: Manufacturer Eisai Manufacturing Limited Mosquito Way Hatfield
Croatian: Eisai Manufacturing Limited Mosquito Way Hatfield
English: The recommended dose is generally 4 to 10 capsules to be taken once daily.
Croatian: Preporučena doza općenito iznosi 4 do 10 kapsula koje treba uzeti jedanput na dan.
English: Hypothyroidism generally occurs 4-8 weeks after commencement of therapy.
Croatian: Hipotiroidizam općenito nastaje 4-8 tjedana nakon početka terapije.
English: Tell your doctor if you are taking, have recently taken or might take any other medicines, such as
Croatian: Obavijestite svog liječnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove, kao što su
English: Targretin should be taken with food (see section 3).
Croatian: Targretin treba uzimati s hranom (pogledajte dio 3).
English: They may notice these changes and help you identify any problems that you need to talk to your doctor about.
Croatian: Oni bi mogli primijetiti te promjene i pomoći Vam da prepoznate tegobe o kojima trebate razgovarati s liječnikom.
English: Hypervitaminosis A.
Croatian: Hipervitaminoza A.
English: Although some patients have improvement within the first several weeks, most patients require several months or more of treatment to improve.
Croatian: Iako u nekih bolesnika nastupi poboljšanje u prvih nekoliko tjedana, većini je bolesnika potrebno nekoliko mjeseci liječenja ili dulje do poboljšanja.
English: The mechanism of this interaction is unknown.
Croatian: Mehanizam ove interakcije nije poznat.
English: Contains sorbitol.
Croatian: Sadrži sorbitol.
English: Do not stop taking your medication until your doctor advises you to do so.
Croatian: Nemojte prestati uzimati svoj lijek sve dok Vam to ne savjetuje liječnik.
English: If you forget to take one dose, take your daily dose with your next meal on the same day, then take your usual dose as normal, the following day.
Croatian: Ako zaboravite uzeti jednu dozu, uzmite svoju dnevnu dozu sa sljedećim obrokom istog dana, zatim uzmite svoju uobičajenu dozu kao i obično, sljedećeg dana.
English: 60528 Frankfurt am Main Germany
Croatian: 60528 Frankfurt am Main Njemačka
English: You may not notice some changes in your mood and behaviour and so it is very important that you tell your friends and family that this medicine could affect your mood and behaviour.
Croatian: Budući da sami možda nećete primijetiti promjene raspoloženja i ponašanja, vrlo je važno da kažete prijateljima i obitelji da bi ovaj lijek mogao utjecati na Vaše raspoloženje i ponašanje.
English: If you are taking a hormonal contraceptive (for example, birth control pills), you should discuss this with your doctor.
Croatian: Ako uzimate hormonsku kontracepciju (na primjer, tablete za kontrolu začeća), trebate o tome razgovarati s Vašim liječnikom.
English: Do not take a double dose in one day to make up for a forgotten dose the previous day.
Croatian: Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu od prethodnog dana.
English: System Organ Class (MedDRA terminology
Croatian: Klasifikacija organskih sustava (MedDRA terminologija)
English: Tell your doctor as soon as possible if you feel any deterioration in your condition while you are taking Targretin.
Croatian: Obavijestite svog liječnika čim prije ako osjetite ikakvo pogoršanje stanja dok uzimate Targretin.
English: The frequencies of adverse reactions are classified as very common (>1/10), common (>1/100, <1/10), uncommon (>1/1,000, <1/100), rare (>1/10,000, <1/1,000), and very rare (<1/10,000).
Croatian: Učestalosti nuspojava kategorizirane su kao vrlo često (>1/10), često (>1/100, <1/10), manje često (>1/1000, <1/100), rijetko (>1/10 000, <1/1000) i vrlo rijetko (<1/10 000).
English: The capsules can be taken immediately before, during or immediately after the course of the meal, if preferred.
Croatian: Kapsule se mogu uzeti neposredno prije, tijekom ili neposredno poslije obroka, po želji.
English: Minimise exposure to sunlight as much as possible and avoid exposure to sun lamps.
Croatian: Izlaganje sunčevom svjetlu svedite na najmanju moguću mjeru i izbjegavajte izlaganje svjetiljkama za sunčanje.
English: Sometimes it is necessary to adjust the dose or interrupt treatment.
Croatian: Ponekad je neophodno prilagoditi dozu ili prekinuti liječenje.
English: Initial dose calculations according to body surface area are as follows:
Croatian: Početna doza izračunava se prema površini tijela na sljedeći način:
English: 60528 Frankfurt am Main Germany e-mail: medinfo_de@eisai.net
Croatian: 60528 Frankfurt am Main Njemačka e-mail: medinfo_de@eisai.net
English: Terminal elimination half-life values were generally between one and three hours.
Croatian: Vrijednosti poluvijeka eliminacije općenito su se kretale između jedan i tri sata.
English: Take your prescribed number of capsules at the same time each day with a meal.
Croatian: Uzmite propisan broj kapsula svakog dana u isto vrijeme uz obrok.
English: Bexarotene is not genotoxic.
Croatian: Beksaroten nije genotoksičan.
English: Your doctor should determine how long you should take Targretin, and when treatment may be stopped.
Croatian: Vaš liječnik treba odrediti koliko dugo ćete uzimati Targretin i kada se može prestati s liječenjem.
English: Total daily dose (mg/day)
Croatian: Ukupna dnevna doza (mg/dan)
English: Treatment should be continued as long as the patient is deriving benefit.
Croatian: Liječenje treba nastaviti sve dok bolesnik od toga ima koristi.
English: Other medicines and Targretin
Croatian: Drugi lijekovi i Targretin
English: Of the total number of patients with CTCL in clinical studies, 61% were 60 years or older, while 30% were 70 years or older.
Croatian: Od ukupnog broja bolesnika s CTCL u kliničkim ispitivanjima, 61% bilo je u dobi od 60 godina ili starije, dok je 30% bilo u dobi od 70 godina ili starije.
English: DO NOT use Targretin if you are pregnant or breast-feeding.
Croatian: NEMOJTE uzimati Targretin ako ste trudni ili dojite.
English: No overall differences in safety were observed between patients 70 years or older and younger patients, but greater sensitivity of some older individuals to bexarotene cannot be ruled out.
Croatian: Općenito nisu bile opažene razlike u sigurnosti primjene između bolesnika u dobi od 70 godina ili starijih i onih mlađih, ali ne može se isključiti veća osjetljivost nekih starijih osoba na beksaroten.
English: Patients receiving bexarotene should not donate blood for transfusion.
Croatian: Bolesnici koji primaju beksaroten ne smiju donirati krv za transfuziju.
English: Very common (can occur in more than 1 in 10 patients treated): Low white blood cell count.
Croatian: Vrlo često (mogu nastati u više od 1 na 10 liječenih bolesnika): Nizak broj bijelih krvnih stanica.
English: Excipient(s) with known effect: sorbitol
Croatian: Pomoćna(e) tvar(i) s poznatim učinkom: sorbitol
English: When toxicity is controlled, doses may be carefully readjusted upward.
Croatian: Kad je toksičnost pod kontrolom, doze se mogu pažljivo ponovno prilagoditi na više razine.
English: Whenever contraception is required, it is recommended that two reliable forms of contraception be used simultaneously.
Croatian: Kadgod je potrebna kontracepcija, preporučuje se istodobno primjenjivati dva pouzdana oblika kontracepcije.
English: Do not store above 30C.
Croatian: Ne čuvati na temperaturi iznad 30 C.
English: Children and adolescents Targretin capsules should not be used in children or adolescents.
Croatian: Djeca i adolescenti Targretin kapsule ne smiju se primjenjivati u djece i adolescenata.
English: The safety and efficacy of bexarotene in children (aged below 18 years) have not been established.
Croatian: Sigurnost i djelotvornost beksarotena u djece (u dobi do 18 godina) nisu ustanovljene.
English: Targretin may be harmful to a developing foetus.
Croatian: Targretin može biti štetan za fetus u razvoju.
English: The aetiology of this finding is unknown.
Croatian: Etiologija ovog nalaza nije poznata.
English: If you regularly consume grapefruit or grapefruit juice, please consult your doctor as these have the potential to alter your body's response to Targretin therapy.
Croatian: Ako redovito konzumirate grejp ili sok od grejpa, molimo da potražite savjet liječnika, jer to može promijeniti odgovor Vašeg organizma na terapiju Targretinom.
English: Paediatric population Targretin is not recommended in children (aged below 18 years).
Croatian: Pedijatrijska populacija Targretin se ne preporučuje u djece (u dobi do 18 godina).
English: Pharmacokinetics in Special Populations
Croatian: Farmakokinetika u posebnih populacija
English: Any overdose should be treated with supportive care for the signs and symptoms exhibited by the patient.
Croatian: Svako predoziranje treba liječiti potpornom skrbi prema znakovima i simptomima koje bolesnik pokazuje.
English: - if you are allergic to bexarotene or any of the other ingredients of this medicine (listed in section
Croatian: - ako ste alergični na beksaroten ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: - if you have ever had any mental health problems including depression, aggressive tendencies or mood changes.
Croatian: - ako ste ikada imali psihičkih tegoba, uključujući depresiju, sklonost agresiji ili promjene raspoloženja.
English: Targretin contains a small amount of sorbitol, therefore patients with rare hereditary problems of fructose intolerance should not take this medicine.
Croatian: Targretin sadrži malu količinu sorbitola; stoga bolesnici s rijetkim nasljednim poremećajem nepodnošenja fruktoze ne smiju uzimati ovaj lijek.