FrancophonIA/ELRC3.0 huggingface dataset:
English: The overall number of death at week 36 was slightly higher in the iNO group; 53/395 (13.4 %) as compared to control 42/397 (10.6 %).
Maltese: In-numru globali ta' mwiet f'ġimgħa 36 kien daqsxejn ogħla fil-grupp li ngħata iNO; 53/395 (13.4%) meta mqabbel mal-kontroll 42/397 (10.
English: MM/YYYY
Maltese: U L- UŻU
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.
Maltese: Informazzjoni dettaljata dwar din il-mediċina tinsab fuq is-sit elettroniku tal-Aġenzija Ewropea għallMediċini http://www.ema.europa.eu/.
English: Most of it traverses the pulmonary capillary bed where it combines with haemoglobin that is 60 % to 100 % oxygen-saturated.
Maltese: Ħafna minnu jgħaddi minn fuq is-sodda kapillari pulmonari fejn jingħaqad mal-emoglobina li hija 60% to 100% saturata bl-ossiġnu.
English: A 2 litre gas cylinder filled at 155 bar absolute brings 307 litres of gas under pressure of 1 bar at 15oC.
Maltese: Ċilindru tal-gass ta' 2 litri mimli f'155 bar assoluti jġib 307 litri ta' gass taħt pressjoni ta' 1 bar fi 15oC.
English: Studies show that nitric oxide exhibits pulmonary pharmacodynamic effects at intra-airway concentrations as low as 1 ppm.
Maltese: Studji urew li nitric oxide juri effetti farmakodinamiċi pulmonari f'konċentrazzjonijiet fil-passaġġ tal-arja minn ġewwa baxxi sa 1 ppm.
English: LT-08300, Vilnius Tel.: +370 2787787 administracija@lt.aga.com
Maltese: +370 2787787 administracija@lt.aga.com
English: Other medicines and INOmax
Maltese: Mediċini oħra u INOmax
English: INOmax appears to increase the partial pressure of arterial oxygen (PaO2) by dilating pulmonary vessels in better ventilated areas of the lung, redistributing pulmonary blood flow away from lung regions with low ventilation/perfusion (V/Q) ratios toward regions with normal ratios.
Maltese: INOmax jidher li jżid il-pressjoni parzjali tal-ossiġnu arterjali (PaO2) billi jwessa' l-vini pulmonari f'żoni vventilati aħjar tal-pulmun, jerġa' jqassam il-fluss ta' demm pulmonari 'l bogħod mir-reġjuni tal-pulmun bi proporzjonijiet ta' ventilazzjoni/perfużjoni baxxi (V/Q) lejn reġjuni bi proporzjonijiet normali.
English: Persistent pulmonary hypertension of the newborn (PPHN) occurs as a primary developmental defect or as a condition secondary to other diseases such as meconium aspiration syndrome (MAS), pneumonia, sepsis, hyaline membrane disease, congenital diaphragmatic hernia (CDH), and pulmonary hypoplasia.
Maltese: Pressjoni pulmonari għolja fit-tarbija tat-twelid (PPHN) isseħħ bħala difett primarju tal-iżvilupp jew bħala kundizzjoni sekondarja għall-mard l-ieħor bħal meconium aspiration syndrome (MAS), pnewmonja, sepsis, mard tal-membrana ijalina, ftuq dijaframmatiku konġenitali (CDH), u hypoplasia pulomonari.
English: PHARMACEUTICAL FORM AND CONTENTS Inhalation gas
Maltese: GĦAMLA FARMAĊEWTIKA U KONTENUT
English: Data further suggested a lack of additional benefit for the higher dose of nitric oxide.
Maltese: Aktar dejta uriet nuqqas ta' benefiċċju addizzjonali għad-doża ogħla ta' nitric oxide.
English: INOmax should not be used in preterm baby < 34 weeks of gestational age.
Maltese: INOmax ma għandux jintuża f'tarbija ta' qabel iż-żmien < 34 ġimgħa tal-età ta' ġestazzjoni.
English: Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for > 70 % of the nitric oxide dose inhaled.
Maltese: In-nitrat ġie identifikat bħala l-metabolit predominanti ta' nitric oxide li joħroġ fl-awrina, u li jammonta għal > 70% tan-nitric oxide li ttieħed man-nifs.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/01/194/003, EU/1/01/194/004
Maltese: TAL-AWTORIZZAZZJONI GĦAT-TQEGĦID FIS-SUQ EU/1/01/194/003, EU/1/01/194/004
English: At this level of oxygen saturation, nitric oxide combines predominantly with oxyhaemoglobin to produce methaemoglobin and nitrate.
Maltese: nitric oxide jingħaqad predominantement ma' oxyhaemoglobin biex jipproduċi methaemoglobin u nitrata.
English: In the CINRGI trial, 186 term- and near-term neonates with hypoxic respiratory failure and without lung hypoplasia were randomised to receive either INOmax (n=97) or nitrogen gas (placebo; n=89) with an initial dose of 20 ppm weaning to 5 ppm in 4 to 24 hours with median duration of exposure of 44 hours.
Maltese: Fil-prova CINRGI, 186 tarbija tat-twelid li twieldu wara li għamlu l-perjodu ta' ġestazzjoni kollu jew qrib il-perjodu ta' ġestazzjoni kollu b'kollass respiratorju ipossiku u mingħajr ipoplażja tal-pulmun ntgħażlu b'mod każwali biex jirċievu jew INOmax (n=97) jew gass tan-nitroġenu (plaċebo; n=89) b'doża inizjali ta' 20 ppm li tiftam sa 5 ppm f'4 sa 24 siegħa b'dewmien medjan ta' esponiment ta'
English: The installation of a nitric oxide pipeline system with supply station of gas cylinders, fixed network and terminal units is forbidden.
Maltese: L-installazzjoni ta' sistema ta' pajpijiet ta' nitric oxide bi stazzjoni ta' forniment ta' ċilindri tal-gass, netwerk fiss u unitajiet terminali hija pprojbita.
English: The dose of nitric oxide should be reduced if the concentration of nitrogen dioxide exceeds 0.5 ppm.
Maltese: Id-doża ta' nitric oxide għandha titnaqqas jekk il-konċentrazzjoni ta' nitrogen dioxide taqbeż 0.5 ppm.
English: Weaning
Maltese: manifattur
English: MARKETING AUTHORISATION NUMBER(S) EU/1/01/194/001, EU/1/01/194/002
Maltese: TAL-AWTORIZZAZZJONI GĦAT-TQEGĦID FIS-SUQ EU/1/01/194/001, EU/1/01/194/002
English: The dose may be increased up to 20 ppm if the lower dose has not provided sufficient clinical effects.
Maltese: Id-doża tista' tiżdied sa 20 ppm jekk id-doża aktar baxxa ma tkunx ipprovdiett effetti kliniċi suffiċjenti.
English: The dose may be increased up to 40 ppm if the lower dose has not provided sufficient clinical effects.
Maltese: Id-doża tista' tiżdied sa 40 ppm jekk id-doża aktar baxxa ma tkunx ipprovdiet effetti kliniċi suffiċjenti.
English: A 10 litre gas cylinder filled at 155 bar absolute brings 1535 litres of gas under pressure of 1 bar at 15oC.
Maltese: Ċilindru tal-gass ta' 10 litri mimli f'155 bar assoluti jġib 1535 litri ta' gass taħt pressjoni ta' 1 bar fi 15oC.
English: AGA Gas AB, Linde Healthcare SE-181 81 Lidingö Tel: + 46 8 7311800/020 790 151 healthcare@se.aga.com
Maltese: Tel: + 46 8 7311800/020 790 151 healthcare@se.aga.com
English: A 2 litre gas cylinder filled at oC. A 10 litre gas cylinder filled
Maltese: Ċilindru tal-gass ta' 10 litri
English: Within the pulmonary system, nitric oxide can combine with oxygen and water to produce nitrogen dioxide and nitrite, respectively, which interact with oxyhaemoglobin to produce methaemoglobin and nitrate.
Maltese: Fi ħdan is-sistema pulmonari, nitric oxide jista jingħaqad mal-ossiġnu u lilma biex jipproduċi nitrogen dioxide u nitrite, rispettivament, li jinteraġixxu ma' oxyhaemoglobin biex jipproduċu methaemoglobin u nitrate.
English: The nitric oxide delivery system for intermittent flow ventilation should be adequate to avoid spikes in nitric oxide concentration.
Maltese: Is-sistema tal-għoti tan-nitric oxide għall-ventilazzjoni ta' flus intermittenti għandha tkun adegwata biex jiġu evitati żidiet f'daqqa fil-konċentrazzjoni ta' nitric oxide.
English: If it is > 2.5 %, the INOmax dose should be decreased and the administration of reducing medicinal products such as methylene blue may be considered.
Maltese: Jekk tkun > 2.5%, id-doża ta' INOmax għandha titnaqqas u l-għoti tal prodotti mediċinali tat-tnaqqis bħall-methylene blue jista' jiġi ikkunsidrat.
English: Atelectasis a
Maltese: ANNESS I
English: Rapid rebound reactions such as intensified pulmonary vasoconstriction and hypoxia after sudden withdrawal of inhaled nitric oxide therapy has been described, precipitating cardiovascular collapse.
Maltese: Reazzjonijiet ta' rikaduta rapida bħal vasokostrizzjoni pulmonari intensifikata u ipoksja wara rtirar f'daqqa ta' terapija b'nitric oxide li jittieħed man-nifs ġiet deskritta li tippreċipita kollass kardjovaskulari.
English: SK-831 06 Bratislava Tel: +421 2 49 10 25 16 healthcare.sk@linde.com
Maltese: Tel: +421 2 49 10 25 16 healthcare.sk@linde.com
English: FIN-02600 Espoo Puh/Tel: + 358 10 2421 hctilaus@fi.aga.com
Maltese: + 358 10 2421 hctilaus@fi.aga.com
English: In the INOT27 trial, 795 preterm infants (GA<29 weeks) with hypoxic respiratory failure were randomised to receive either INOmax (n=395) in a dose of 5 ppm or nitrogen (placebo n=400),
Maltese: Fil-prova INOT27, 795 tarbija li twieldu qabel iż-żmien (GA<29 ġimgħa) b'insuffiċjenza respiratorja ipossika ġew randomizzati sabiex jirċievu jew INOmax (n=395) f'doża ta' 5 ppm jew nitroġenu (plaċebo n=400), li jibdew fi żmien l-ewwel 24 siegħa tal-ħajja u jiġu trattati għal mill-inqas 7 ijiem, sa 21 ġurnata.
English: INOmax 400 ppm mol/mol inhalation gas Nitric oxide
Maltese: INOmax 400 ppm mol/mol gass għat-teħid man-nifs Nitric oxide
English: Bradycardia (low cardiac frequency) or too low amount of oxygen in the blood (oxygen desaturation/hypoxemia) due to sudden withdrawal of the treatment, Headache, dizziness, dry throat or shortness of breath following accidental ambient air exposure to nitric oxide (e.g. leakage from equipment or cylinder).
Maltese: Bradikardja (frekwenza kardijaka baxxa) jew ammont baxx ħafna ta' ossiġnu fid-demm (desaturazzjoni tal-ossiġnu/ipoksemja) minħabba twaqqif f'daqqa tat-trattament, Uġigħ ta' ras, sturdament, griżmejn xotti jew qtugħ ta' nifs wara espożizzjoni aċċidentali talarja ambjentali għan-nitric oxide (eż. tnixxija minn apparat jew ċilindru).
English: Accidental exposure to INOmax in hospital staff has been associated with adverse events (see section 4.8).
Maltese: Espożizzjoni aċċidentali għal INOmax f'persunal tal-isptar ġiet assoċjata ma' avvenimenti avversi (ara sezzjoni 4.8).
English: AUTHORISATION
Maltese: LISTA
English: The dose should be incrementally reduced to 1 ppm for 30 minutes with close observation of systemic and central pressure, and then turned off. Weaning should be attempted at least every 12 hours when the patient is stable on a low dose of INOmax.
Maltese: Id-doża għandha titnaqqas b'mod inkrimentali għal 1 ppm għal 30 minuta b'monitoraġġ mill-qrib tal-pressjoni sistemika u ċentrali, u mbagħad tintefa.
English: How to store INOmax
Maltese: Tużax INOmax
English: From a corrosion point of view the supply system can be divided into two zones: 1) From the gas cylinder valve to the humidifier (dry gas) and 2) From the humidifier to outlet (moist gas which may contain NO2).
Maltese: Minn lat ta' korrużjoni, is-sistema ta' forniment tista' tinqasam f'żewġ żoni: 1) Mill-valv taċ-ċilindu tal-gass għall-umidifikatur (gass xott) u 2) Millumidifikatur għall-iżbokk (gass niedi li jista' jkun fih NO2).
English: - Setting the NO, NO2 and O2 monitors for high and low alarm limits - Using the manual backup delivery system - Procedures for correctly switching gas cylinders and purging system - Troubleshooting alarms - NO, NO2 and O2 monitor calibration - Monthly system performance check-up procedures
Maltese: - Issettjar tal-apparat għall-konċentrazzjoni t-tajba ta' nitric acid li trid tingħata - Issettjar tal-monitors tal-NO, NO2 u O2 għal-limiti ta' allarm baxxi u għoljin - Użu tas-sistema ta' backup ta' għoti manwali
English: In the NINOS trial, 235 neonates with hypoxic respiratory failure were randomised to receive 100 % O2 with (n=114) or without (n=121) nitric oxide most with an initial concentration of 20 ppm with weaning as possible to lower doses with a median duration of exposure of 40 hours.
Maltese: Fil-prova NINOS, 235 tarbija tat-twelid b'kollass respiratorju ipossiku ntagħżlu b'mod każwali biex jirċievu 100% O2 bi (n=114) jew mingħajr (n=121) nitric oxide, ħafna minnhom b'konċentrazzjoni inizjali ta' 20 ppm bi ftim possibbli għal dożi iktar baxxi b'dewmien medjan ta' esponiment ta' 40 siegħa.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Nitric oxide (NO) 800 ppm mol/mol.
Maltese: DIKJARAZZJONI TAS-SUSTANZA(I) ATTIVA(I) Nitric oxide (NO) 800 ppm mol/mol.
English: Overdose with INOmax will be manifest by elevations in methaemoglobin and NO2.
Maltese: Doża eċċessiva ta' INOmax timmanifesta ruħha b'elevazzjonijiet fil-methaemoglobin u l-NO2.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Nitric oxide (NO) 400 ppm mol/mol.
Maltese: DIKJARAZZJONI TAS-SUSTANZA(I) ATTIVA(I) Nitric oxide (NO) 400 ppm mol/mol.
English: The nitrogen dioxide (NO2) concentration and FiO2 must also be measured at the same site using calibrated and approved (CE-marked) monitoring equipment.
Maltese: Il-konċentrazzjoni ta' nitrogen dioxide (NO2) u FiO2 għandhom jitkejlu wkoll fl-istess sit bl-użu ta' apparat ta' monitoraġġ ikkalibrat u approvat (immarkat-CE).
English: as part of the treatment of peri- and post-operative pulmonary hypertension in adults and newborn infants, infants and toddlers, children and adolescents, ages 0-17 years in conjunction to heart surgery, in order to selectively decrease pulmonary arterial pressure and improve right ventricular function and oxygenation.
Maltese: bħala parti mit-trattament ta' pressjoni pulmonari għolja waqt u wara operazzjoni f'persuni adulti u trabi tat-twelid, trabi u tfal li għadhom kif telqu jimxu, tfal u adoloxxenti, età 0-17-il sena flimkien ma' operazzjoni tal-qalb, sabiex titnaqqas b'mod selettiv il-pressjoni fl-arterji pulmonari u jittejbu l-funzjoni u l-ossiġenazzjoni tal-ventrikolu tal-lemin.
English: There is an increased risk of methaemoglobin formation if substances with a known tendency to increase methaemoglobin concentrations are administered concomitantly with nitric oxide (e.g. alkyl nitrates and sulphonamides).
Maltese: Hemm riskju akbar li tifforma l-methaemoglobin jekk is-sustanzi magħrufin li għandhom tendenza li jżidu l-konċentrazzjonijiet ta' methaemoglobin jingħataw flimkien man-nitric oxide (eż. alkyl nitrates u sulphonamides).
English: Nitric oxide may react with oxygen forming nitrogen dioxide that may cause airway irritation.
Maltese: Nitric oxide jista' jirreaġġixxi mal-ossiġenu u jifforma nitrogen dioxide li jista' jikkawża irritazzjoni fil-passaġġ tal-arja.
English: Available data suggest additive effects on central circulation, pulmonary artery pressure and right ventricular performance.
Maltese: Dejta disponibbli tissuġġerixxi effetti addittivi fuq iċ-ċirkolazzjoni ċentrali, il-pressjoni tal-arterji pulmonari u l-prestazzjoni tal-ventrikolu tal-lemin.
English: H-1097 Budapest Tel.: +361 347 4843 healthcare@hu.linde-gas.com
Maltese: +361 347 4843 healthcare@hu.linde-gas.com
English: Methaemoglobin disposition has been investigated as a function of time and nitric oxide exposure concentration in neonates with respiratory failure.
Maltese: Id-dispożizzjoni ta' methaemoglobin ġiet investigata fi trabi tat-twelid b'insuffiċjenza respiratorja bħala funzjoni taż-żmien u l-esponiment għall-konċentrazzjoni ta' nitric oxide.
English: INOmax 800 ppm mol/mol inhalation gas Nitric oxide
Maltese: INOmax 800 ppm mol/mol gass għat-teħid man-nifs Nitric oxide.
English: It relaxes vascular smooth muscle by binding to the haeme moiety of cytosolic guanylate cyclase, activating guanylate cyclase and increasing intracellular levels of cyclic guanosine 3',5'-monophosphate, which then leads to vasodilation.
Maltese: Dan jirrilassa l-muskolu morbidu vaskulari billi jeħel mal-haeme moiety tas-cytosolic guanylate cyclase, tattiva l-guanylate cyclase u żżid il-livelli intraċellulari ta' cyclic guanosine 3',5'-monophosphate, li mbagħad iwassal għal vasodilazzjoni.
English: Neonates with less than a full response at 20 ppm were evaluated for a response to 80 ppm nitric oxide or control gas.
Maltese: ossiġenazzjoni tal-membrana ekstrakorporali (ECMO). Trabi tat-twelid b'inqas minn rispons sħiħ f'20 ppm kienu evalwati għal rispons għal 80 ppm nitric oxide jew gass ta' kontroll.
English: Care must be taken when INOmax is given at the same time as medicinal products containing prilocaine.
Maltese: Trid tingħata attenzjoni meta INOmax jingħata fl-istess ħin li jingħataw prodotti mediċinali li fihom prilocaine.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Nitric oxide (NO) 400 ppm mol/mol.
Maltese: Nitric oxide (NO) 400 ppm mol/mol.
English: Pulmonary hypertension associated with heart surgery Prescription of nitric oxide should be supervised by a physician experienced in cardiothoracic anaesthesia & intensive care.
Maltese: Il-preskrizzjoni ta' nitric oxide għandha tiġi sorveljata minn tabib b'esperjenza f'anastesija kardjotorarċika u fil-kura intensiva.
English: In biological tissue, nitric oxide may form peroxynitrite with superoxide (O2-), an unstable compound which may cause tissue damage through further redox reactions.
Maltese: Fit-tessut bijoloġiku, nitric oxide jista' jifforma peroxynitrite b'superoxide (O2-), sustanza instabbli li tista' tikkawża ħsara lit-tessut permezz ta' aktar reazzjonijet ta' ossidazzjoni u tiċkin.
English: SE-181 81 Lidingö
Maltese: Linde Healthcare AB SE-181 81 Lidingö
English: In clinical studies, NO2 levels > 3 ppm or methaemoglobin levels > 7 % were treated by reducing the dose of, or discontinuing, INOmax.
Maltese: Fi studji kliniċi, il-livelli tal-NO2 > 3 ppm jew il-livelli tal-methaemoglobin > 7% ġew ikkurati billi tnaqqset jew twaqqfet id-doża ta' INOmax.
English: However, the presence of nitrogen dioxide and moisture creates an aggressive atmosphere.
Maltese: Madankollu, il-preżenza ta' nitrogen dioxide u umdità toħloq ambjent aggressiv.
English: If there is no change in oxygenation during administration of INOmax at 1 ppm, the FiO2 should be increased by 10 %, the INOmax is discontinued, and the neonates monitored closely for signs of hypoxaemia.
Maltese: Jekk ma jkunx hemm bidla fl-għoti ta' ossiġnu waqt l-għoti ta' INOmax f'1 ppm, l-FiO2 għandha titnaqqas b'10%, jitwaqqaf INOmax, u t-trabi tat-twelid għandhom jiġu immonitorjati millqrib għal sinjali ta' livell baxx ħafna ta' ossiġnu fid-demm (hypoxaemia).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Nitric oxide (NO) 800 ppm mol/mol.
Maltese: Nitric oxide (NO) 800 ppm mol/mol.
English: A clinically significant interaction with other medicinal products used in the treatment of hypoxic respiratory failure cannot be excluded based on the available data.
Maltese: Effett klinikament sinifikanti ma' prodotti mediċinali oħra użati fil-kura ta' kollass respiratorju ipossiku ma jistax jiġi eskluż skont id-dejta disponibbli.
English: Methaemoglobin levels > 7 % were attained only in patients receiving 80 ppm, where they comprised 35 % of the group.
Maltese: Il-livelli ta' methaemoglobin > 7% inkisbu biss f'pazjenti li kienu qed jirċievu 80 ppm, li kienu jiffurmaw 35% tal-grupp.
English: Nitric oxide is genotoxic in some test systems.
Maltese: L-ossidu nitriku huwa ġenotossiku f'xi sistemi ta' ttestjar.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 01/08/2001
Maltese: Data tal-ewwel awtorizzazzjoni: 01/08/2001
English: The end medicinal products of nitric oxide that enter the systemic circulation are predominantly methaemoglobin and nitrate.
Maltese: nitric oxide li jidħlu fiċ-ċirkolazzjoni sistemika huma predominantement methaemoglobin u nitrata.
English: The safety and efficacy of INOmax in premature infants less than 34 weeks of gestation has not yet been established.
Maltese: Is-sigurtà u l-effikaċja ta' INOmax fi trabi prematuri b'inqas minn 34 ġimgħa ta' ġestazzjoni, ma ġewx determinati s'issa.
English: In patients undergoing heart surgery, an increase in pulmonary artery pressure due to pulmonary vasoconstriction is frequently seen.
Maltese: F'pazjenti li jkunu qegħdin jagħmlu kirurġija tal-qalb, żieda fil-pressjoni arterjali pulmonari minħabba vaskostrizzjoni pulmonari tidher b'mod frekwenti.
English: This leaflet was last revised in MM/YYYY.
Maltese: Espożizzjonijiet ogħla ma ġewx investigati.
English: - Keep this leaflet.
Maltese: Popolazzjonijiet ta' pazjenti speċjali
English: Nitrogen dioxide (NO2) is the main substance formed, and may cause airway inflammation and damage.
Maltese: Nitrogen dioxide (NO2) huwa s-sustanza ewlenija ffurmata, u jista' jikkawża infjammazzjoni tal-passaġġ tal-arja u ħsara.
English: Newborn infants, infants and toddlers, children and adolescents, ages 0-17 years The starting dose of inhaled nitric oxide is 10 ppm(part per million) of inhaled gas.
Maltese: Trabi tat-twelid, trabi u trabi li għadhom kif telqu jimxu, tfal u adoloxxenti, ta' età minn 0-17-il sena Id-doża tal-bidu ta' nitric oxide meħud man-nifs hija 10 ppm(parti għal kull miljun) ta' gass meħud man-nifs.
English: Attempts to wean INOmax should be made after the ventilator support is substantially decreased or after 96 hours of therapy.
Maltese: Tentattivi biex INOmax jinfatam għandhom isiru wara li titnaqqas l-għajnuna permezz tal-ventilatur jew wara 96 siegħa ta' terapija.
English: NO2 rapidly forms in gas mixtures containing nitric oxide and O2, and nitric oxide may in this way cause airway inflammation and damage.
Maltese: Formazzjoni ta' NO2 NO2 malajr jifforma f'taħlitiet ta' gass li fihom in-nitric oxide u O2, u n-nitric oxide jista' b'dan il mod jikkawża infjammazzjoni jew ħsara fil-passaġġ.
English: Methaemoglobin level should be measured within one hour after initiation of INOmax therapy, using an analyser which can reliably distinguish between foetal haemoglobin and methaemoglobin.
Maltese: Il-livell ta' Methaemoglobin għandu jitkejjel fi żmien siegħa wara li tkun inbdiet it-terapija b'INOmax, bl-użu ta' analizzatur li b'mod affidabbli jista' jiddistingwi bejn haemoglobin tal-fetu u methaemoglobin.
English: When inhaled, nitric oxide produces selective pulmonary vasodilation.
Maltese: Meta jittieħed man-nifs, nitric acid jipproduċi vasodilazzjoni pulmonari selettiva.
English: BRAILLE Justification for not including Braille accepted
Maltese: Il-ġustifikazzjoni biex ma jkunx inkluż il-Braille hija aċċettata
English: All equipment, including connectors, tubing, and circuits, used in the delivery of nitric oxide must be made of materials compatible with the gas.
Maltese: L-apparat kollu, inkluż it-tqabbid, il-pajpjiet u ċirkwiti, użati fil-forniment ta' nitric oxide għandu jkun magħmul minn materjali kompatibbli mal-gass.
English: Do not discard used gas cylinders.
Maltese: Tarmix ċilindri tal-gass użati.
English: Return to distributor / manufacturer - a gas cylinder whose valve is not protected by a cap or a shell should not be used - a specific connection, with a 30 mm thread which is designated for medical use, complying with ISO 5145 and a pressure regulator which admits a pressure at least equal to 1.5 the maximum operating pressure (155 bar) of the gas cylinder should be used - the pressure regulator should be purged by the nitrogen-nitric oxide mixture before each new use in order to preclude nitrogen dioxide inhalation - the pressure regulator should not be tightened with pliers, at the risk of crushing the gasket
Maltese: - Tqabbid maċ-ċilindru tal-gass u maċ-ċirkwit tal-ventilatur għat-teħid ta' nifs mill-pazjent Tħaddim - Minn qabel uża l-proċedura tal-lista ta' verifika (serje ta' passi meħtieġa immedjatament qabel l-inizjazzjoni ta' kull pazjent biex jiġi żgurat li s-sistema tkun qed taħdem sewwa u li s-sistema hija mnaddfa mill-NO2) - Issettjar tal-apparat għall-konċentrazzjoni t-tajba ta' nitric acid li trid tingħata - Issettjar tal-monitors tal-NO, NO2 u O2 għal-limiti ta' allarm baxxi u għoljin - Użu tas-sistema ta' backup ta' għoti manwali - Proċeduri biex iċ-ċilindri tal-gass jinbidlu u s-sistema titnaddaf kif suppost
English: METHOD AND ROUTE(S) OF ADMINISTRATION Endotracheopulmonary use.
Maltese: Metodu ta' kif għandu jingħata Għal użu endotrakeopulmonari.
English: Dyspnoeac Chest Discomfortc Dry throat c
Maltese: Jekk inti jew it-tifel/tifla tiegħek tirċievu
English: The clinical significance of the chemical reactivity of nitric oxide in tissue is unknown.
Maltese: Is-sinifikat kliniku tar-reattività kimika ta' nitric oxide fit-tessut mhuwiex magħruf.
English: In the presence of oxygen, nitric oxide is rapidly oxidised to derivatives which are toxic to the bronchial epithelium and alveolo-capillary membrane.
Maltese: Fil-preżenza ta' ossiġnu, nitric oxide jossidizza b'mod mgħaġġel f'derivattivi li huma tossiċi għall bronchial epithelium u l-membrana kapillari tal-alveoli.