FrancophonIA/ELRC3.0 huggingface dataset:
English: Data from a randomised trial in patients with juvenile rheumatoid arthritis (aged 2.8 to 15.1 years) indicated greater oral bioavailability of methotrexate in the fasting state.
Slovenian: 2,8 do 15,1 leta) so pokazali večjo peroralno biološko uporabnost metotreksata na tešče.
English: Hepatic steatosis, fibrosis and cirrhosis, Decrease in serum albumin
Slovenian: jetrna steatoza, fibroza in ciroza, znižanje koncentracije serumskega albumina akutni hepatitis in hepatotoksičnost,
English: 3 has been reported for methotrexate used in rheumatologic and related indications 4 see remarks on liver biopsy in section 4.4
Slovenian: 4 Glejte pripombe o biopsiji jeter v poglavju 4.4.
English: If pregnancy occurs during treatment with methotrexate and up to six months thereafter, medical advice should be given regarding the risk of harmful effects on the child associated with treatment and ultrasonography examinations should be performed to confirm normal foetal development.
Slovenian: se mora nosečnica posvetovati z zdravnikom glede tveganja za škodljive učinke na otroka, ki so povezani z zdravljenjem, za preverjanje, ali se plod normalno razvija, pa je treba opraviti ultrazvočne preglede.
English: − dizziness, confusion, seizures
Slovenian: − omotica, zmedenost, krči, − okvara pljuč,
English: Malignant lymphomas
Slovenian: Maligni limfomi
English: painful urination
Slovenian: − boleče ali oteženo uriniranje,
English: Pancreatitis, Enteritis, Malabsorption, Melaena, Gingivitis
Slovenian: driska razjede in krvavitve prebavnega trakta pankreatitis, enteritis, malabsorpcija, melena, gingivitis toksični megakolon,
English: The combination of methotrexate and sulfasalazine can enhance the effect of methotrexate, as sulfasalazine causes inhibition of folic acid synthesis.
Slovenian: Kombinacija metotreksata in sulfasalazina lahko z zaviranjem sinteze folne kisline s sulfasalazinom poveča učinkovitost metotreksata.
English: Name and address of the manufacturer responsible for batch release Quay Pharmaceuticals Limited
Slovenian: Ime in naslov izdelovalca, odgovornega za sproščanje serij
English: Treatment of rheumatoid arthritis, severe juvenile idiopathic arthritis, severe psoriasis and severe psoriatic arthritis with Jylamvo is a long-term treatment.
Slovenian: Zdravljenje revmatoidnega artritisa, hudega juvenilnega idiopatičnega artritisa, hude luskavice in hudega psoriatičnega artritisa z zdravilom Jylamvo je dolgotrajno.
English: The active substance is methotrexate.
Slovenian: Učinkovina je metotreksat.
English: Doses exceeding 20 mg (10 ml)/week can be associated with a substantial increase in toxicity, especially bone marrow depression.
Slovenian: Odmerki, ki presegajo 20 mg (10 ml)/teden, so lahko povezani s precejšnjim povečanjem toksičnosti, zlasti z zaviranjem delovanja kostnega mozga.
English: − serious disorder of bone marrow (anaemia), swollen glands
Slovenian: − resne motnje v delovanju kostnega mozga (anemija), otečene žleze,
English: Dermatitis and sunburn
Slovenian: Dermatitis in sončne opekline
English: During methotrexate therapy, concurrent vaccination with live vaccines should be avoided (see sections 4.3 and 4.4).
Slovenian: Sočasno cepljenje z živimi cepivi se med zdravljenjem z metotreksatom ne sme izvajati (glejte poglavji 4.3 in 4.4).
English: Particular caution is also required in the presence of inactive chronic infections (e.g. herpes zoster, tuberculosis, hepatitis B or C) as it is possible that activation of these infections may occur.
Slovenian: − imate neaktivno, dolgotrajno okužbo (npr. tuberkulozo, hepatitis B ali C, pasovca [herpes zoster], saj lahko ponovno izbruhne;
English: Animal studies showed that the administration of NSAIDs including salicylic acid resulted in reduced tubular methotrexate secretion and accordingly potentiated its toxic effects.
Slovenian: vključno s salicilno kislino, povzročila zmanjšano tubularno izločanje metotreksata in posledično povečala njegove toksične učinke.
English: STATEMENT OF ACTIVE SUBSTANCE(S)
Slovenian: Opozorila v zvezi s pomožnimi snovmi
English: For non-oncological indications, in women of child-bearing age the possibility of a pregnancy must be ruled out, e.g. by pregnancy tests, before treatment is started.
Slovenian: Pri neonkoloških indikacijah je treba pri ženskah v rodni dobi pred začetkom zdravljenja z ustreznimi metodami, kot je test nosečnosti, izključiti nosečnost.
English: − worsening of psoriasis during treatment with UV therapy
Slovenian: − poslabšanje luskavice med zdravljenjem z obsevanjem z UV-žarki,
English: • Pre-existing blood disorders such as bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anaemia
Slovenian: − imate krvne bolezni, kot so hipoplazija kostnega mozga, levkopenija, trombocitopenija ali izrazita anemija;
English: Methotrexate should be used with caution in patients with impaired renal function (see section 4.4).
Slovenian: Pri bolnikih z okvarjenim delovanjem ledvic je treba metotreksat uporabljati previdno (glejte poglavje 4.4).
English: Cholestyramine can increase the non-renal elimination of methotrexate by interfering with the enterohepatic circulation.
Slovenian: Holestiramin lahko z motenjem enterohepatičnega obtoka poveča neledvično izločanje metotreksata.
English: − liver failure
Slovenian: Okvara jeter
English: − skin rash, skin redness and itching.
Slovenian: − kožni izpuščaj, pordelost kože in srbenje.
English: Very rare (may affect up to 1 in 10,000 people):
Slovenian: Zelo redki (pojavijo se lahko pri največ 1 od 10 000 bolnikov):
English: Jylamvo is for use in the following indications:
Slovenian: Zdravilo Jylamvo se uporablja pri bolnikih:
English: Nocardiosis, Histoplasma and cryptococcus mycosis, Disseminated herpes simplex
Slovenian: herpes zoster sepsa okužbe, ki jih povzroča citomegalovirus nokardioza, histoplazma in kriptokokna mikoza, diseminirani herpes simpleks
English: − unconsciousness
Slovenian: − nespečnost,
English: Methotrexate temporarily affects sperm and egg production.
Slovenian: Metotreksat prizadene tvorbo semenske tekočine in jajčec.
English: In non-oncologic indications, the absence of pregnancy must be confirmed before Jylamvo is used.
Slovenian: Pri neonkoloških indikacijah je treba pred uporabo zdravila Jylamvo izključiti nosečnost.
English: Certain brain disorders (encephalopathy/leukoencephalopathy) have been reported in cancer patients receiving methotrexate.
Slovenian: Pri nekaterih bolnikih, ki so prejemali metotreksat, so poročali o določenih okvarah možganov (encefalopatiji/levkoencefalopatiji).
English: In the antineoplastic treatment, myelosuppression and mucositis are the predominant dose-limiting toxic effects of methotrexate.
Slovenian: Pri zdravljenju z antineoplastičnimi zdravili sta prevladujoča toksična učinka metotreksata, ki omejujeta odmerek, mielosupresija in mukozitis.
English: For protection, you should wear disposable gloves when handling Jylamvo.
Slovenian: Pri rokovanju z zdravilom Jylamvo za lastno zaščito nosite rokavice za enkratno uporabo.
English: The medicinal product can be taken with or without food.
Slovenian: Zdravilo Jylamvo se lahko jemlje s hrano ali brez nje.
English: − acute hepatitis (inflammation of the liver)
Slovenian: − akutni hepatitis (vnetje jeter),
English: Bone marrow depression (severe courses),
Slovenian: megaloblastna anemija depresija kostnega mozga (hudi poteki),
English: Effective clearance of methotrexate is reported to be achieved with acute intermittent haemodialysis using a high-flux dialyser.
Slovenian: Poročali so o učinkovitem očistku metotreksata z akutno, intermitentno visokopretočno hemodializo.
English: Painful erosions of psoriatic plaque,
Slovenian: povečanje števila revmatičnih vozličev, boleče erozije psoriatičnega plaka,
English: There is a risk of excessive immunosuppression with risk of lymphoproliferation when the combination is used.
Slovenian: Če se uporablja kombinirano zdravljenje, hkrati s tveganjem limfoproliferacije obstaja tudi tveganje prekomerne imunosupresije.
English: Jylamvo 2 mg/ml oral solution methotrexate
Slovenian: Jylamvo 2 mg/ml peroralna raztopina metotreksat
English: Remember to inform your doctor about the treatment with Jylamvo if you are prescribed another medicine during treatment.
Slovenian: Če vam je med zdravljenjem predpisano drugo zdravilo, ne pozabite obvestiti zdravnika o zdravljenju z zdravilom Jylamvo.
English: − reduced blood cell formation with a decrease in white and/or red blood cells and/or platelets
Slovenian: − zmanjšana tvorba krvnih celic z zmanjšanjem števila belih in/ali rdečih krvnih celic in/ali krvnih ploščic (levkopenija, anemija, trombocitopenija), − glavobol, utrujenost, vrtoglavica,
English: Treatment of active rheumatoid arthritis, severe JIA, severe psoriasis and severe psoriatic arthritis represents a long-term treatment.
Slovenian: Zdravljenje aktivnega revmatoidnega artritisa, hudega juvenilnega idiopatičnega artritisa (JIA), hude psoriaze in hudega psoriatičnega artritisa je dolgotrajno.
English: − inflammation of the heart sac, accumulation of fluid in the heart sac
Slovenian: − vnetje osrčnika, nabiranje tekočine v osrčniku,
English: Depression Mood swings Insomnia
Slovenian: Psihiatrične motnje depresija nihanja razpoloženja nespečnost
English: − liver diseases, reduced content of blood proteins
Slovenian: − razjede in krvavitve v prebavilih, − bolezni jeter, znižane vrednosti beljakovin v krvi,
English: Hepatobiliary disorders
Slovenian: hematemeza dispepsija
English: • Recommendation to monitor patients for signs and symptoms of overdose (these predominantly affect the haematopoietic and gastrointestinal systems)
Slovenian: • priporočilo o spremljanju bolnikov glede pojava znakov in simptomov prevelikega odmerjanja
English: Prompt investigations should be considered when pulmonary alveolar haemorrhage is suspected to confirm the diagnosis.
Slovenian: Ob sumu na pljučno alveolarno krvavitev so potrebne takojšnje preiskave za potrditev diagnoze.
English: − seizures (convulsions)
Slovenian: − epileptični krči (konvulzije),
English: Take the medicine pack with you when you visit your doctor or the hospital.
Slovenian: Ob odhodu k zdravniku ali v bolnišnico vzemite s seboj škatlo z zdravilom.
English: Skin toxicity
Slovenian: Toksični učinki na koži
English: If you suffer from diarrhoea please speak to your doctor.
Slovenian: Če imate drisko, se posvetujte z zdravnikom.
English: Pruritus vasculitis, herpetiform skin eruptions, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), Increased rheumatic nodules,
Slovenian: vaskulitis, herpetiformni izbruhi na koži, Stevens-Johnson ov sindrom,
English: − bone damage in the jaw (secondary to excessive growth of white blood cells).
Slovenian: − krvavitev iz pljuč*, − odmiranje čeljustne kosti (ki nastanejo zaradi prevelike rasti belih krvničk).
English: Keep the bottle tightly closed to prevent spoilage of the medicine and reduce the risk of accidental spillage.
Slovenian: Da bo zdravilo ostalo neokrnjeno in da zmanjšate tveganje nenamernega razlitja, naj bo steklenička tesno zaprta.
English: Severe, occasionally fatal, dermatologic reactions, including toxic epidermal necrolysis (Lyell's syndrome) or Stevens-Johnson syndrome have been reported after single or multiple doses of methotrexate.
Slovenian: Po enkratnem odmerku ali večkratnih odmerkih metotreksata so poročali o hudih, občasno smrtnih dermatoloških reakcijah, vključno s toksično epidermalno nekrolizo (Lyellovim sindromom) ali
English: The doctor may increase the dose if the used dose is not effective but tolerated well.
Slovenian: Če predpisani odmerek ni učinkovit, bolnik pa ga dobro prenaša, ga lahko zdravnik poveča.
English: Ethyl parahydroxybenzoate (E214) Sodium methyl parahydroxybenzoate (E219) Citric acid monohydrate
Slovenian: FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi makrogol 400 glicerol aroma pomaranče sukraloza etilparahidroksibenzoat (E214) natrijev metilparahidroksibenzoat (E219) citronska kislina monohidrat trinatrijev citrat prečiščena voda
English: In the event of (prior) treatment with medicinal products that can have adverse reactions on bone marrow (e.g. sulphonamides, trimethoprim/sulphamethoxazole, chloramphenicol, pyrimethamine), the possibility of haematopoietic disorders must be considered.
Slovenian: (npr. sulfonamidi, trimetoprim/sulfametoksazol, kloramfenikol, pirimetamin), je treba upoštevati možnost hematopoetskih motenj.
English: Thromboembolic reactions (including arterial and cerebral thrombosis, thrombophlebitis, deep leg vein thrombosis, retinal vein thrombosis, pulmonary embolism), Hypotension
Slovenian: (vključno z arterijsko in možgansko trombozo, tromboflebitisom , globoko vensko trombozo, vensko trombozo mrežnice,
English: Radiation-induced dermatitis and sunburn can reappear during methotrexate therapy (recall reactions).
Slovenian: Med zdravljenjem z metotreksatom se lahko znova pojavijo dermatitis, ki ga povzroči obsevanje, in sončne opekline (spominske reakcije).
English: • Patient Card
Slovenian: • opozorilno kartico za bolnika.
English: The other ingredients are: macrogol 400, glycerol, orange flavour, sucralose, ethyl parahydroxybenzoate (E214), sodium methyl parahydroxybenzoate (E219), citric acid, tri-sodium citrate, purified water.
Slovenian: etilparahidroksibenzoat (E214), natrijev metilparahidroksibenzoat (E219), citronska kislina, trinatrijev citrat, prečiščena voda.
English: Concurrent vaccination using live vaccines should not be given.
Slovenian: Cepljenja z živimi cepivi se med zdravljenjem z metotreksatom ne sme izvajati.
English: Telangiectasis, Hidradenitis
Slovenian: akutna zanohtnica, furunkuloza teleangiektazija hidradenitis
English: Your doctor will therefore do tests to check for any changes in your blood (such as a low white blood cell count, a low blood platelet count, lymphomas), kidneys or liver.
Slovenian: Zato bo zdravnik opravil preiskave, s katerimi bo preveril morebitne spremembe v krvi (npr. nizko število belih krvnih celic,
English: Most frequently (very common) observed adverse reactions of methotrexate include gastrointestinal disorders (e.g. stomatitis, dyspepsia, abdominal pain, nausea, loss of appetite) and abnormal liver function tests (e.g. increased alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), bilirubin, alkaline phosphatase).
Slovenian: Najpogostejši (zelo pogosti) opaženi neželeni učinki metotreksata vključujejo bolezni prebavil (npr. stomatitis, dispepsijo, bolečine v trebuhu, navzejo, izgubo teka) in nenormalne teste jetrne funkcije
English: Eosinophilia, Neutropenia, Lymphadenopathy
Slovenian: limfoproliferativna bolezen2, eozinofilija, nevtropenija, limfadenopatija krvavitve
English: − mood swings
Slovenian: − nihanja razpoloženja,
English: - if you have a weakened immune system - if you are suffering from a serious infection such as tuberculosis or HIV - if you have ulcers in the stomach or in the intestines - if you have an inflammation of the mucous membrane of the mouth or mouth ulcers - if you are pregnant or breast-feeding (see section “Pregnancy, breast-feeding and fertility”) - if you have had a live vaccine recently or are about to have one
Slovenian: − ste noseči ali dojite (glejte poglavje „Nosečnost, dojenje in plodnost“); − ste bili pred kratkim cepljeni ali če boste cepljeni z živim cepivom.
English: Pain,
Slovenian: − driska,
English: Such side effects cannot be excluded when methotrexate is used to treat other diseases.
Slovenian: Če se metotreksat uporablja za zdravljenje drugih bolezni, takšnih neželenih učinkov ni mogoče izključiti.
English: Due to its potentially toxic effects on the liver, additional hepatotoxic medicinal products should not be taken during treatment with methotrexate unless urgently necessary and the consumption of alcohol should be avoided or reduced (see section 4.5).
Slovenian: - Zaradi morebitnega toksičnega učinka na jetra se med zdravljenjem z metotreksatom ne smejo uporabljati dodatna hepatotoksična zdravila, razen če je to nujno potrebno.
English: The use of nitrous oxide potentiates the effect of methotrexate on folate metabolism, yielding increased toxicity such as severe, unpredictable myelosuppression, stomatitis and neurotoxicity with intrathecal administration.
Slovenian: kar povzroči povečano toksičnost, ki se lahko izrazi v obliki hude, nepredvidljive mielosupresije, stomatitisa in nevrotoksičnosti.
English: Jylamvo contains ethyl parahydroxybenzoate and sodium methyl parahydroxybenzoate
Slovenian: Zdravilo Jylamvo vsebuje etilparahidroksibenzoat in natrijev metilparahidroksibenzoat
English: The dose should be adjusted as follows for patients with rheumatoid arthritis, juvenile arthritis, psoriasis and psoriatic arthritis.
Slovenian: Pri bolnikih z revmatoidnim artritisom, juvenilnim artritisom, psoriazo in psoriatičnim artritisom je treba odmerek prilagoditi.
English: Insufficient data is available for methotrexate exposure during pregnancy higher than 30 mg (15 ml)/week, but higher rates of spontaneous abortions and congenital malformations are expected, in particular at doses commonly used in oncologic indications
Slovenian: vendar se pričakujejo višje stopnje spontanih splavov in kongenitalnih malformacij, še zlasti pri odmerkih, ki se pogosto uporabljajo pri onkoloških indikacijah.
English: − kidney disease, inflammation or ulcers of the bladder (possibly also with blood in the urine),
Slovenian: − bolezen ledvic, vnetje ali razjede sečnega mehurja (lahko se pojavi kri v urinu), boleče uriniranje, − vnetje in draženje v nožnici.
English: Psoriatic lesions can worsen during UV radiation and co-administration of methotrexate.
Slovenian: psoriatične lezije se lahko s sočasnim obsevanjem z UV-žarki poslabšajo, dermatitis,
English: − nausea, vomiting, abdominal discomfort or severe diarrhoea
Slovenian: − navzeja, bruhanje, neprijeten občutek v trebuhu ali huda driska,
English: − inflammation of the lungs (pneumonia) with dry cough, shortness of breath and fever
Slovenian: − vnetje pljuč (pljučnica) s suhim kašljem, zadihanostjo in zvišano telesno temperaturo,
English: How to store Jylamvo
Slovenian: Shranjevanje zdravila Jylamvo
English: Take Jylamvo only once a week for the treatment of rheumatic or skin diseases (RA, JIA and psoriasis or psoriatic arthritis).
Slovenian: Zdravilo Jylamvo jemljite samo enkrat na teden pri zdravljenju revmatskih ali kožnih bolezni (RA,
English: Malignant lymphomas may occur in patients receiving low dose methotrexate, in which case therapy must be discontinued.
Slovenian: Pri bolnikih, ki jemljejo majhne odmerke metotreksata, se lahko pojavijo maligni limfomi.
English: Methotrexate should be administered only with the greatest caution, if at all, in patients with significant existing or previous liver disease, especially if due to alcohol.
Slovenian: Pri bolnikih s hudim trenutnim ali nedavnim obolenjem jeter, zlasti če je ta posledica alkohola, je treba metotreksat, če sploh, uporabljati zelo previdno.
English: Methotrexate should be used only with great caution, if at all, in patients who have a significant liver disease, particularly if this is/was alcohol-related.
Slovenian: Pri bolnikih s hudo boleznijo jeter, zlasti če je ta posledica alkohola, je treba metotreksat, če sploh,
English: Patients with rheumatological or dermatological diseases must be informed unequivocally that treatment is to be taken just once a week and not daily.
Slovenian: Revmatološke ali dermatološke bolniki je treba jasno opozoriti na to, da se zdravilo uporablja samo enkrat tedensko in ne vsak dan. Nepravilna uporaba metotreksata lahko povzroči hude neželene učinke, ki so lahko celo smrtni.
English: You should avoid fathering a child or to donate semen during treatment with methotrexate and for at least 6 months after the end of treatment.
Slovenian: Med zdravljenjem z metotreksatom in še vsaj šest mesecev po koncu zdravljenja se morate izogibati spočetju otroka ali darovanju semenske tekočine.
English: Closer monitoring of liver enzymes should be undertaken in patients taking other hepatotoxic medicinal products concomitantly (e.g. leflunomide).
Slovenian: Pri bolnikih, ki sočasno prejemajo druga hepatotoksična zdravila (npr. leflunomid), je treba skrbno spremljati jetrne encime.
English: − fingernail infections, detachment of the nail from the nail bed, boils, widening of small blood vessels, damage to the blood vessels of the skin, allergic inflammation of blood vessels
Slovenian: − vnetje nohtov, odstopanje nohtov od nohtne posteljice, bule, razširitev malih krvnih žil,
English: Put on disposable gloves before handling.
Slovenian: Konico brizge za odmerjanje potisnite v odprtino nastavka.
English: − a blood disorder characterised by the appearance of very large red blood cells (megaloblastic anaemia)
Slovenian: Redki (pojavijo se lahko pri največ 1 od 1 000 bolnikov): − krvna motnja, za katero je značilen pojav zelo velikih rdečih krvničk (megaloblastna anemija),
English: The risk of an interaction between NSAIDs and methotrexate should be considered in patients with a low methotrexate dose, particularly in the case of impaired kidney function.
Slovenian: Pri bolnikih, zdravljenih z majhnimi odmerki metotreksata, še posebno pri tistih z okvarjenim delovanjem ledvic, je treba upoštevati medsebojno delovanje nesteroidnih protivnetnih zdravil in metotreksata.
English: In addition, pulmonary alveolar haemorrhage has been reported with methotrexate used in rheumatologic and related indications.
Slovenian: 3 O tem so poročali pri uporabi metotreksata pri revmatoloških in sorodnih indikacijah.
English: Immunosuppression, Allergic vasculitis (severe toxic symptom), Hypogammaglobulinaemia
Slovenian: anafilaktični šok, zvišana telesna temperatura, mrzlica imunosupresija, alergijski vaskulitis (hud simptom toksičnosti),
English: Allergic reactions, Anaphylactic shock,
Slovenian: Bolezni imunskega sistema alergijske reakcije,
English: Renal failure, Oliguria, Anuria, Azotaemia
Slovenian: (po možnosti s hematurijo), disurija ledvična odpoved, oligurija, anurija, azotemija proteinurija
English: Respiratory, thoracic and mediastinal disorders
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora intersticijski alveolitis/pljučnica
English: Megaloblastic anaemia
Slovenian: aplastična anemija,
English: Oral solution.
Slovenian: Peroralna uporaba.
English: Diarrhoea can be a possible side effect of Jylamvo and requires an interruption of therapy.
Slovenian: Možen neželeni učinek zdravila Jylamvo je driska; če se pojavi, je treba zdravljenje prekiniti.
English: - diuretics, that reduce fluid retention - medicines for lowering blood sugar levels such as metformin
Slovenian: − zdravila za zniževanje ravni glukoze v krvi, kot je metformin, − retinoide (za zdravljenje luskavice in drugih bolezni kože),
English: Symptoms include leucocytopenia, thrombocytopenia, anaemia, pancytopenia, neutropenia, myelosuppression, mucositis, stomatitis, oral ulceration, nausea, vomiting, gastrointestinal ulceration and bleeding.
Slovenian: Simptomi vključujejo levkopenijo, trombocitopenijo, anemijo, pancitopenijo, nevtropenijo,
English: Treatment should not be initiated or should be discontinued if there are any abnormalities in liver function tests or liver biopsies, or if these develop during therapy.
Slovenian: Če se med preiskavami delovanja jeter ali biopsijami jeter odkrijejo kakršne koli bolezenske spremembe ali če te nastanejo med zdravljenjem, se zdravljenje ne sme začeti oziroma ga je treba prekiniti.
English: The possibility of delayed methotrexate clearance should be considered in combination with other cytostatic medicinal products.
Slovenian: Pri sočasni uporabi metotreksata z drugimi citostatičnimi zdravili je treba upoštevati, da je lahko očistek metotreksata zakasnel.
English: This oral solution contains 2 mg methotrexate in 1 ml solution and the scaling of the dosing syringe is in ml and not mg.
Slovenian: Opozorila in previdnostni ukrepi Pomembno opozorilo glede odmerjanja zdravila Jylamvo (metotreksat): Ta peroralna raztopina vsebuje 2 mg metotreksata v 1 ml raztopine, merilne enote na brizgi za odmerjanje pa so mililitri in ne miligrami.