FrancophonIA/ELRC3.0 huggingface dataset:
English: If you stop taking IOA because you want to get pregnant, you are recommended to wait until you have had a natural period before trying to conceive.
Slovenian: Če prenehate jemati zdravilo IOA, ker želite zanositi, priporočamo, da počakate do prve naravne menstruacije in šele potem skušate zanositi.
English: Nomegestrol acetate and its hydroxylated metabolites undergo extensive phase 2 metabolism to form glucuronide- and sulphate conjugates.
Slovenian: Nomegestrolacetat in njegovi hidroksilirani presnovki so podvrženi obsežni presnovi druge faze in tvorijo glukuronidne in sulfatne konjugate.
English: Allergic (hypersensitive) reactions have been reported in users of IOA, but the frequency cannot be
Slovenian: Pri uporabnicah zdravila IOA so poročali o alergijskih (preobčutljivostnih) reakcijah, vendar pogostnosti iz razpoložljivih podatkov ni mogoče oceniti.
English: • There is no consensus about the possible role of varicose veins and superficial thrombophlebitis in the onset or progression of venous thrombosis.
Slovenian: • O možni vlogi varikoznih ven in povrhnjega tromboflebitisa pri pojavu in napredovanju venske tromboze ni soglasja.
English: All adverse reactions are listed by system organ class and frequency; very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100) and rare (≥ 1/10,000 to < 1/1,000).
Slovenian: (≥1/100 do <1/10), občasni (≥1/1.000 do <1/100) in redki (≥1/10.000 do <1/1.000).
English: Multiple doses up to five times the daily dose of IOA and single doses up to 40 times the daily dose of nomegestrol acetate alone have been used in women without safety concern.
Slovenian: Pri ženskah, ki so zaužile več odmerkov do petkratnika dnevnega odmerka zdravila IOA, oziroma pri tistih, ki so enkrat zaužile do 40-kratnik dnevnega odmerka samega nomegestrolacetata, ni bilo težav glede varnosti.
English: See also ‘General Notes' in section 2
Slovenian: Glejte tudi "Splošno" v poglavju 2 zgoraj.
English: Dose-linearity was observed in the range 0.625-5 mg (assessed in fertile and post-menopausal
Slovenian: Linearno odvisnost so opazili v razponu od 0,625 do 5 mg (merjeno pri plodnih ženskah in pri ženskah po menopavzi).
English: Read all of this leaflet carefully before you start using this medicine because it contains
Slovenian: Pred začetkom uporabe zdravila natančno preberite navodilo, ker vsebuje za vas pomembne podatke!
English: The effectiveness of the pill is maintained, but tell your doctor if you are using anti-fungal medicines
Slovenian: Učinkovitost kontracepcijske tablete je ohranjena, vendar morate zdravniku povedati, če jemljete antimikotike (protiglivična zdravila), ki vsebujejo ketokonazol.
English: • It is not yet known how the risk of a blood clot with IOA compares to the risk with a combined hormonal contraceptive that contains levonorgestrel.
Slovenian: • Ni še znano, kakšno je tveganje za nastanek krvnega strdka med uporabo zdravila IOA v primerjavi s tveganjem med uporabo kombiniranega hormonskega kontraceptiva, ki vsebuje levonorgestrel.
English: If you want to stop IOA because you want to get pregnant, see in section 3 ‘If you stop taking IOA'.
Slovenian: Če želite prenehati z uporabo zdravila IOA, ker želite zanositi, glejte poglavje 3 "Če prenehate z jemanjem zdravila IOA".
English: The IOA blister contains 28 tablets: 24 white tablets with the active substances (number 1-24) and 4 yellow tablets without active substances (number 25-28).
Slovenian: Pretisni omot zdravila IOA vsebuje 28 tablet: 24 belih tablet z zdravilnima učinkovinama (številke 1-24) in 4 rumene tablete brez zdravilnih učinkovin (številke 25-28).
English: Using a combined hormonal contraceptive such as IOA increases your risk of developing a blood clot compared with not using one.
Slovenian: Uporaba kombiniranih hormonskih kontraceptivov, kot je zdravilo IOA, poveča vaše tveganje za nastanek krvnega strdka v primerjavi z neuporabo.
English: In the event of aggravation, or first appearance of any of these conditions or risk factors, the woman should be advised to contact her doctor to determine whether the use of IOA should be discontinued.
Slovenian: Ženski je treba svetovati, da naj se v primeru poslabšanja ali prvega pojava katerega od navedenih stanj ali dejavnikov tveganja posvetuje z zdravnikom, ki bo presodil, ali je treba uporabo zdravila IOA prekiniti.
English: Six multi-centre clinical trials of up to one year duration were used to evaluate safety of IOA.
Slovenian: Za ovrednotenje varnosti zdravila IOA so izvedli šest multicentričnih kliničnih preskušanj v trajanju do enega leta.
English: • diabetes mellitus with vascular symptoms
Slovenian: • sladkorna bolezen s simptomi na ožilju
English: • Extremely rarely, thrombosis has been reported to occur in CHC users in other blood vessels, e.g. hepatic, mesenteric, renal, or retinal veins and arteries.
Slovenian: • Pri uporabnicah KPK so izredno redko poročali o nastanku tromboze tudi v drugih krvnih žilah, npr. v jetrnih, mezenteričnih, ledvičnih, mrežničnih venah in arterijah.
English: As no epidemiological data are yet available with estradiol containing-CHCs, the warnings are considered applicable to the use of IOA.
Slovenian: Ker še ni na voljo epidemioloških podatkov za KHK, ki vsebujejo estradiol, veljajo zadevna opozorila tudi za uporabo zdravila IOA.
English: The increased risk of VTE during the postpartum period should be considered when re-starting IOA (see section 4.2 and 4.4).
Slovenian: Pri ponovni uvedbi zdravila IOA je treba upoštevati povečano tveganje za VTE v obdobju po porodu (glejte poglavji 4.2 in 4.4).
English: • if you are allergic to estradiol or nomegestrol acetate, or any of the other ingredients of this medicine (listed in section 6).
Slovenian: • če ste alergični na estradiol ali nomegestrolacetat ali katero koli sestavino tega zdravila
English: After discontinuation of IOA, return to ovulation in the first 28 days after last tablet intake was
Slovenian: Po prekinitvi jemanja zdravila IOA so pri 79 % žensk opazili povrnitev ovulacije v prvih 28 dneh po zaužitju zadnje tablete.
English: Table: Risk factors for ATE
Slovenian: Preglednica: Dejavniki tveganja za ATE Dejavnik tveganja
English: • It is not yet known how the risk of VTE with CHCs that contain nomegestrol acetate in combination with estradiol compares with the risk with low dose levonorgestrel-containing
Slovenian: • Ni še znano, kakšno je tveganje za VTE pri CHC, ki vsebujejo nomegestrolacetat v kombinaciji z estradiolom, v primerjavi s tveganjem pri CHC, ki vsebujejo majhen odmerek levonorgestrela.
English: [Box for placing day label stating:] Place day label here [Day numbering for each individual tablet:] Start,2, ….28 [Arrows indicating the sequence of the tablets:] →
Slovenian: DRUGI PODATKI [okvirček za dnevno oznako z napisom:] sem prilepite nalepko z dnevnimi oznakami [številka dneva za vsako posamezno tableto:] začetek, 2, ….28
English: The new tablet should be taken within 12 hours of the usual time of tablet-taking if possible.
Slovenian: Če je mogoče, mora novo tableto vzeti v 12 urah po običajnem času za zaužitje tablete.
English: • change in colour of the skin on the leg e.g. turning pale, red or
Slovenian: • spremenjena barva kože na nogi, npr. bleda, pordela ali pomodrela koža,
English: The decision to prescribe IOA should take into consideration the individual woman's current risk factors, particularly those for venous thromboembolism (VTE), and how the risk of VTE with IOA compares with other CHCs (see sections 4.3 and 4.4).
Slovenian: Pri odločitvi, da predpišete zdravilo IOA, je treba upoštevati trenutne dejavnike tveganja pri posameznici, zlasti za vensko trombembolijo (VTE) in kakšno je tveganje za VTE pri zdravilu IOA v primerjavi z drugimi kombiniranimi hormonskimi kontraceptivi (CHC - combined hormonal contraceptives) (glejte poglavji 4.3 in 4.4).
English: • Nomegestrol acetate, the progestogen in IOA, is derived from the hormone progesterone.
Slovenian: • Nomegestrolacetat, to je progestogen v zdravilu IOA, nastane iz hormona progesterona.
English: NAME OF THE MEDICINAL PRODUCT IOA 2.5 mg/1.5 mg film-coated tablets
Slovenian: IME ZDRAVILA IOA 2,5 mg/1,5 mg filmsko obložene tablete
English: • sudden weakness or numbness of the face, arm or leg, especially on
Slovenian: • nenadna šibkost ali omrtvelost obraza, roke ali noge, zlasti na eni strani telesa;
English: • The following conditions have been reported to occur or deteriorate with both pregnancy and COC use, but the evidence of an association with COC use is inconclusive: jaundice and/or pruritus related to cholestasis; gallstone formation; porphyria; systemic lupus erythematosus; haemolytic uraemic syndrome; Sydenham's chorea; herpes gestationis; otosclerosis-related
Slovenian: • Poročali so, da se naslednje bolezni ali motnje pojavijo ali poslabšajo med nosečnostjo in med uporabo KPK, vendar dokazi o povezavi s KPK niso dokončni: zlatenica in/ali pruritus povezan s holestazo, nastanek žolčnih kamnov, porfirija, sistemski eritematozni lupus, hemolitično uremični sindrom, Sydenhamova horeja, herpes gestationis, izguba sluha zaradi otoskleroze.
English: Oxidation of estrone and estradiol involves cytochrome P450 enzymes, mainly CYP1A2, CYP1A2 (extra hepatic), CYP3A4, CYP3A5, and CYP1B1 and CYP2C9.
Slovenian: Pri oksidaciji estrona in estradiola sodelujejo encimi citokroma P450, predvsem CYP1A2, CYP1A2 (zunaj jeter), CYP3A4, CYP3A5 in CYP1B1 ter
English: For example, if you start on a Wednesday, use the day label sticker that starts with ‘WED'.
Slovenian: Če na primer začnete kontracepcijske tablete jemati v sredo, uporabite tisto nalepko z dnevnimi oznakami, ki se začne s
English: Also HIV protease inhibitors with an inducing potential (e.g. ritonavir and nelfinavir) and non-nucleoside reverse transcriptase inhibitors (e.g. nevirapine and efavirenz), may affect hepatic metabolism.
Slovenian: Tudi zaviralci proteaz HIV, ki lahko inducirajo encime (npr. ritonavir in nelfinavir), ter nenukleozidni zaviralci reverzne transkriptaze (npr. nevirapin in evafirenz) lahko vplivajo na jetrno presnovo.
English: Magyarország MSD Pharma Hungary Kft. Tel.: + 36 1 888 5300 hungary_msd@merck.com
Slovenian: MSD Pharma Hungary Kft. Tel.: + 36 1 888 5300 hungary_msd@merck.com
English: Adverse reaction in MedDRA Term1
Slovenian: Neželeni učinki v skladu z MedDRA1 terminologijo
English: - epilepsy (e.g. primidone, phenytoin, phenobarbital, carbamazepine, oxcarbazepine,
Slovenian: - epilepsije (npr. primidon, fenitoin, fenobarbital, karbamazepin, okskarbazepin, topiramat,
English: Do not start the next blister of IOA until your doctor has checked that you are not pregnant.
Slovenian: Nemudoma se posvetujte z zdravnikom in ne začnite z jemanjem tablet iz naslednjega pretisnega omota zdravila IOA, dokler vam zdravnik ne potrdi, da niste noseči.
English: You can delay your period by not taking the yellow placebo tablets and going straight to a new blister of IOA.
Slovenian: Menstruacijo si lahko preložite tako, da ne jemljete rumenih placebo tablet in nadaljujete naravnost z jemanjem tablet iz novega pretisnega omota zdravila IOA.
English: As no epidemiological data are yet available with 17β-estradiol containing CHCs, the contraindications for ethinylestradiol containing CHCs are considered applicable to the use of IOA.
Slovenian: Ker še ni na voljo epidemioloških podatkov o KHK, ki vsebujejo 17β-estradiol, se razume, da kontraindikacije za uporabo KHK, ki vsebujejo etinilestradiol, veljajo tudi za uporabo zdravila IOA.
English: Whether this also applies to 17β-estradiol-containing COCs remains
Slovenian: Če to velja tudi za KPK, ki vsebujejo 17β-estradiol, je treba še potrditi.
English: Combined pills (including IOA tablets) no longer required should not be disposed via wastewater or the municipal sewage system.
Slovenian: Kombinirane kontracepcijske tablete (vključno s tabletami IOA), ki jih ne uporabljate več, ne smete odvreči v odpadne vode ali v sistem javne kanalizacije.
English: • The use of any combined hormonal contraceptive (CHC) increases the risk of venous thromboembolism (VTE) compared with no use.
Slovenian: • Uporaba katerega koli kombiniranega hormonskega kontraceptiva (KPK) poveča tveganje za nastanek venske trombembolije (VTE) v primerjavi z ženskami, ki KPK ne uporabljajo.
English: No epidemiological data on the risk of cervical cancer in
Slovenian: Epidemiološki podatki o tveganju za nastanek raka materničnega vratu pri uporabnicah zdravila
English: In this case you could have a hereditary blood clotting
Slovenian: V takšnem primeru imate morda dedno motnjo strjevanja krvi;
English: In case you use a vaginal ring or transdermal patch, it is best to start using IOA on the day you remove the ring or patch.
Slovenian: Če uporabljate vaginalni obroček ali transdermalni obliž, je najbolje, da z jemanjem zdravila IOA začnete tisti dan, ko odstranite obroček ali obliž.
English: COC tablets (including IOA tablets) no longer required should not be disposed via wastewater or the municipal sewage system.
Slovenian: KPK tablet (vključno s tabletami IOA), ki jih ne uporabljate več, ne smete odvreči v odpadne vode ali v sistem javne kanalizacije.
English: Very common (may affect more than 1 in 10 people):
Slovenian: Pogosti (pojavijo se lahko pri največ 1 od 10 uporabnic):
English: Possibly related adverse reactions that have been reported in clinical trials or during postmarketing use with IOA are listed in the table below.
Slovenian: Tabelarični pregled neželenih učinkov Možno z zdravilom povezani neželeni učinki, o katerih so poročali v kliničnih preskušanjih ali v obdobju trženja zdravila IOA, so podani v spodnji preglednici.
English: In rare cases a blood clot can block blood vessels and cause serious
Slovenian: V redkih primerih lahko krvni strdek zamaši žile in povzroči resne težave.
English: Maximum serum concentrations of estradiol are about 90 pg/ml and are reached 6 h after dosing.
Slovenian: Stanje dinamičnega ravnovesja Največja serumska koncentracija estradiola znaša približno 90 pg/ml in je dosežena 6 h po zaužitju zdravila.
English: There have been no reports of serious harmful effects from taking too many IOA tablets at one time.
Slovenian: Če ste vzeli večji odmerek zdravila IOA, kot bi smeli Ni nobenih poročil o resnih škodljivih učinkih zaradi zaužitja prevelikega števila tablet zdravila IOA naenkrat.
English: Influence of other medicinal products on IOA
Slovenian: Vpliv drugih zdravil na zdravilo IOA
English: When changing from an injectable, IOA should be started on the day when the next injection would have been due.
Slovenian: Pri prehodu z injekcij naj začne ženska jemati zdravilo IOA na dan, ko bi bila na vrsti naslednja injekcija.
English: Another method of contraception should be used to avoid unintentional pregnancy.
Slovenian: Za preprečitev neželene nosečnosti je treba uporabiti drug način
English: IOA is contraindicated if a woman has one serious or multiple risk factors for ATE that puts her at high risk of arterial thrombosis (see section 4.3).
Slovenian: Zdravilo IOA je kontraindicirano, če ima ženska en resen ali več dejavnikov tveganja za ATE, zaradi katerih ima veliko tveganje za arterijsko trombozo (glejte poglavje 4.3).
English: Obesity (body mass index over 30 kg/m2)
Slovenian: Debelost (indeks telesne mase nad 30 kg/m2)
English: • if you are very overweight (body mass index or BMI over 30kg/m2);
Slovenian: • če imate zelo prekomerno telesno maso (indeks telesne mase [ITM] več kot 30kg/m2);
English: • Although COCs may have an effect on peripheral insulin resistance and glucose tolerance, there is no evidence for a need to alter the therapeutic regimen in diabetics using low-dose COCs (containing < 0.05 mg ethinylestradiol).
Slovenian: • Čeprav lahko KPK vplivajo na odpornost perifernih tkiv na insulin in glukozno toleranco, ni nobenih dokazov, da bi bilo treba pri sladkornih bolnicah, ki jemljejo nizko odmerne KPK (z < 0,05 mg etinilestradiola), kakor koli spremeniti režim zdravljenja, vendar je treba sladkorne bolnice skrbno spremljati med jemanjem KPK, še posebej v prvih mesecih njihove uporabe.
English: IOA comes in 1 or 3 blisters of 28 film-coated tablets (24 white active film-coated tablets and 4 yellow placebo film-coated tablets) packed in a ply carton.
Slovenian: Zdravilo IOA je na voljo v 1 ali 3 pretisnih omotih po 28 filmsko obloženih tablet (24 belih aktivnih filmsko obloženih tablet in 4 rumene placebo filmsko obložene tablete), pakiranih v kartonske škatle.
English: • if a member of your immediate family has had a heart attack or stroke at a young age (less than about 50).
Slovenian: • če je imel vaš bližnji sorodnik srčni infarkt ali možgansko kap v mlajših letih (pred približno
English: When doing so, no additional contraceptive measures are necessary.
Slovenian: zato dodatni ukrepi niso potrebni.
English: Like all medicines, IOA can cause side effects, although not everybody gets them.
Slovenian: Možni neželeni učinki Kot vsa zdravila ima lahko tudi zdravilo IOA neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Merck Sharp & Dohme Ireland (Human Health)
Slovenian: Merck Sharp & Dohme Ireland (Human Health) Limited
English: To delay a period the woman should continue with another blister pack of IOA without taking the yellow placebo tablets from her current pack.
Slovenian: Če želi ženska odložiti menstruacijo, naj nadaljuje z jemanjem tablet iz drugega pretisnega omota zdravila IOA ne da bi jemala rumene placebo tablete iz trenutnega pretisnega omota.
English: No studies were conducted to evaluate the effect of hepatic disease on the pharmacokinetics of IOA.
Slovenian: Študij za oceno vpliva ledvičnih bolezni na farmakokinetiko zdravila IOA niso izvedli.
English: • All 24 white film-coated tablets are active tablets that contain a small amount of two different female hormones.
Slovenian: • Vseh 24 belih filmsko obloženih tablet predstavlja aktivne tablete, ki vsebujejo majhno količino dveh različnih ženskih hormonov, to je nomegestrolacetata (progestogena) in estradiola
English: • if you, or someone in your immediate family, have a high level of fat in the blood (cholesterol
Slovenian: • če imate vi ali kdo od vaših bližnjih sorodnikov visoko koncentracijo maščob v krvi (holesterol ali trigliceride),
English: If the woman is less than 12 hours late in taking any active tablet, contraceptive protection is not reduced.
Slovenian: Če ženska zamuja z jemanjem katere koli tablete z zdravilno učinkovino manj kot 12 ur, kontracepcijska zaščita ni zmanjšana.
English: 1The most appropriate MedDRA term to describe a certain adverse reaction is listed.
Slovenian: 1Za opis določenega neželenega učinka je uporabljen najprimernejši izraz v skladu z MedDRA terminologijo.
English: The following advice only refers to missed white active tablets.
Slovenian: Naslednji nasveti se nanašajo samo na primer, da ste pozabili vzeti belo aktivno tableto.
English: Symptoms of a cerebrovascular accident can include: - sudden numbness or weakness of the face, arm or leg, especially on one side of the body; - sudden trouble walking, dizziness, loss of balance or coordination; - sudden confusion, trouble speaking or understanding; - sudden trouble seeing in one or both eyes; - sudden, severe or prolonged headache with no known cause; - loss of consciousness or fainting with or without seizure.
Slovenian: Med simptomi cerebrovaskularnega dogodka so lahko: - nenadna omrtvelost ali šibkost obraza, roke ali noge, zlasti na eni strani telesa, - nenadne težave s hojo, omotica, izguba ravnotežja ali koordinacije, - nenadna zmedenost, težave z govorom ali razumevanjem,
English: Due to metabolism and enterohepatic circulation, a large circulating pool of estrogen sulfates and glucuronides is present.
Slovenian: Zaradi presnove in enterohepatičnega obtoka kroži po telesu velika količina estrogen sulfatov in glukuronidov.
English: However, if intercourse has already occurred, pregnancy should be excluded before the actual start of COC use or the woman has to wait
Slovenian: Če pa je vmes že imela spolni odnos, je treba najprej izključiti nosečnost, preden lahko ženska začne jemati kombinirane peroralne kontraceptive, oziroma mora ženska počakati na prvo menstruacijo.
English: In the IOA group, acne was reported by 15.4 % of the women (versus 7.9 % in the comparator group), weight increased was reported by 8.6 % of the women (versus 5.7 % in the comparator group), and abnormal withdrawal bleeding (predominantly absence of withdrawal bleeding) was reported by 10.5 % of the women (versus 0.5 % in the comparator group).
Slovenian: V skupini, ki je jemala zdravilo IOA, je o aknah poročalo 15,4 % žensk (proti 7,9 % v primerjalni skupini), o povečanju telesne mase 8,6 % žensk
English: o A high risk of venous thromboembolism due to the presence of multiple risk factors (see
Slovenian: o Veliko tveganje za vensko trombembolijo zaradi prisotnosti večih dejavnikov tveganja
English: • Worsening of depression, Crohn's disease and ulcerative colitis have been associated with COC use.
Slovenian: • Z uporabo KPK je bilo povezano poslabšanje depresije, Crohnove bolezni in ulceroznega kolitisa.
English: Ferric oxide yellow (E172)
Slovenian: črni železov oksid (E 172)
English: Factors that increase your risk of a blood clot in a vein The risk of a blood clot with IOA is small but some conditions will increase the risk.
Slovenian: Tveganje za nastanek krvnega strdka je z zdravilom IOA majhno, vendar pa nekatera stanja to tveganje povečajo.
English: • Please be alert and see your doctor if you think you may have symptoms of a blood clot (see
Slovenian: • Bodite pozorni in pojdite k zdravniku, če menite, da imate simptome krvnega strdka (glejte poglavje 2 "Krvni strdki").
English: - sweating, nausea, vomiting or dizziness; - extreme weakness, anxiety, or shortness of breath; - rapid or irregular heartbeats.
Slovenian: - znojenje, navzea, bruhanje ali omotica, - skrajna šibkost, tesnoba ali kratka sapa, - hitro ali neredno bitje srca.
English: The user should take the last missed tablet as soon as she remembers, even if this means taking two tablets at the same time.
Slovenian: Zadnjo pozabljeno belo tableto naj ženska vzame takoj, ko se spomni, tudi če to pomeni, da bo vzela dve tableti hkrati.
English: IOA, like other hormonal contraceptives, does not protect against HIV infection (AIDS) or any
Slovenian: Tako kot druga hormonska kontracepcijska sredstva tudi zdravilo IOA ne varuje pred okužbo z virusom HIV (AIDS) ali katero drugo spolno prenosljivo boleznijo.
English: • Estradiol, the oestrogen in IOA, is identical to the hormone produced by your ovaries during a
Slovenian: • Estradiol, to je estrogen v zdravilu IOA, je popolnoma enak hormonu, ki nastaja v jajčnikih v času menstrualnega ciklusa.
English: Symptoms of deep vein thrombosis (DVT) can include: - unilateral swelling of the leg and/or foot or along a vein in the leg; - pain or tenderness in the leg which may be felt only when standing or walking; - increased warmth in the affected leg; red or discoloured skin on the leg.
Slovenian: Med simptomi globoke venske tromboze (DVT) so lahko: - enostranska oteklost noge in/ali stopala ali vzdolž vene na nogi, - bolečina ali občutljivost v nogi, ki je lahko prisotna le stoje ali med hojo,
English: IOA is contraindicated if a woman has multiple risk factors that put her at high risk of venous thrombosis (see section 4.3).
Slovenian: Zdravilo IOA je kontraindicirano, če ima ženska več dejavnikov tveganja, zaradi katerih je njeno tveganje za vensko trombozo veliko (glejte poglavje 4.3).
English: However, if she has missed more than 1 tablet, the woman should be advised to use extra precautions for 7 days.
Slovenian: Če pa ste izpustili več kot 1 tableto, morate 7 dni uporabljati dodatna kontracepcijska sredstva.
English: Other medical conditions associated with VTE Cancer, systemic lupus erythematosus, haemolytic uraemic syndrome, chronic inflammatory bowel disease (Crohn's disease or ulcerative colitis) and sickle cell disease
Slovenian: Rak, sistemski eritematozni lupus, hemolitičnouremični sindrom, kronična vnetna bolezen črevesja (Crohnova bolezen ali ulcerozni kolitis)