FrancophonIA/ELRC3.0 huggingface dataset:
English: Handle with care!” and “Please replace needle cap” are shown until the needle cap is put back on.
Estonian: Käsitsege ettevaatlikult!” ja “Palun asetage nõelale kork” ilmuvad ekraanile seni, kuni nõela kork on tagasi asetatud.
English: What Cimzia looks like and contents of the pack
Estonian: Kuidas Cimzia välja näeb ja pakendi sisu
English: • You can now remove the used pen by pulling the pen straight up carefully from the skin.
Estonian: • Nüüd võite kasutatud pen-süstli eemaldada, tõmmates seda ettevaatlikult naha pinnalt otse üles.
English: Some patients with an initial partial response may subsequently improve with continued treatment beyond 16 weeks.
Estonian: Mõnel algselt osalise ravivastuse saavutanud patsiendil võib pärast 16 nädalat seisund ravi jätkamisel edaspidi paraneda.
English: Patients had ≥ 3 swollen and tender joints and increased acute phase reactants.
Estonian: Patsientidel oli ≥ 3 turses ja valulikku liigest ja ägeda faasi reaktiivsuse näitajad kõrgenenud.
English: CIMPASI-1 and CIMPASI-2 evaluated 234 patients and 227 patients respectively.
Estonian: Uuringutes CIMPASI-1 ja CIMPASI-2 hinnati vastavalt 234 ja 227 patsienti.
English: However, if any of the following steps go wrong and/or if you feel unsure about the injection process, contact your doctor or pharmacist.
Estonian: Siiski, kui mõni järgnevatest sammudest läheb valesti ja/või kui te tunnete ennast süstimisprotsessi suhtes ebakindlalt, pöörduge oma arsti või apteekri poole.
English: The physician should discuss with the patient which injection presentation option is the most appropriate.
Estonian: Arst peab patsiendiga arutama, milline süstevahendi tüüp on kõige sobilikum.
English: Data from more than 500 prospectively collected pregnancies exposed to Cimzia with known pregnancy outcomes, including more than 400 pregnancies exposed during the first trimester, does not indicate a malformative effect of Cimzia.
Estonian: Prospektiivselt kogutud andmed rohkem kui 500 Cimzia'ga kokku puutunud ja teadaolevate rasedustulemustega raseduse kohta, mille moodustavad rohkem kui 400 rasedust kokkupuutega esimese trimestri jooksul, ei viita väärarengute tekkele Cimzia'ga.
English: Major clinical response is defined as achieving ACR 70 response at every assessment over a continuous 6-month period
Estonian: Kliiniliselt oluline ravivastus on defineeritud kui ACR 70 ravivastuse saavutamine igal hindamisel järjepideva 6-kuulise perioodi jooksul
English: Only the highest titers were associated with reduced certolizumab pegol plasma levels, however, no impact on efficacy was observed.
Estonian: Üksnes kõrgeimad tiitrid seostati alanenud tsertolizumabpegooli plasmatasemetega, aga ei täheldatud mingit mõju efektiivsusele.
English: The other cases represented a variety of different malignancies and included rare malignancies usually associated with immunosuppression.
Estonian: Ülejäänud juhud olid erinevad pahaloomulised kasvajad, sh harvaesinevad pahaloomulised kasvajad, mida harilikult seostatakse immunosupressiooniga.
English: Do not stop using Cimzia without talking to your doctor first.
Estonian: Ärge lõpetage Cimzia kasutamist ilma oma arstiga nõu pidamata.
English: Table 3 ACR response in clinical trials RA-I and RA-II Study RA-I Methotrexate combination (24 and 52 weeks)
Estonian: Tabel 3 ACR ravivastus uuringutes RA-I ja RA-II Uuring RA-I Kombinatsioon metotreksaadiga (24 ja 52 nädalat)
English: Then, talk to your doctor and inject the following doses as instructed.
Estonian: Seejärel pidage nõu oma arstiga ja süstige järgmised annused vastavalt juhistele.
English: The mean PASI score at baseline was 20 and ranged from 12 to 69.
Estonian: Keskmine ravieelne PASI skoor oli 20, vahemikus 12 kuni 69.
English: This number decreases with increasing doses of concomitant MTX treatment.
Estonian: See väärtus väheneb samaaegsel MTX ravi lisamisel kasvavas annuses.
English: Both doses of Cimzia demonstrated efficacy compared to placebo regardless of age, gender, body weight, BMI, psoriasis disease duration, previous treatment with systemic therapies and previous treatment with biologics.
Estonian: Cimzia mõlema annusega tõestati efektiivsust platseeboga võrreldes, olenemata vanusest, soost, kehakaalust, kehamassiindeksist, psoriaasihaiguse kestusest, varasemast ravist süsteemsete raviviisidega ja varasemast ravist bioloogiliste ainetega.
English: At Week 4 and Week 8, all infant concentrations were BLQ.
Estonian: 4. ja 8. nädalal olid kontsentratsioonid kõigil imikutel määramispiirist väiksemad.
English: • Press the (Start/Pause button).
Estonian: • Vajutage (Start/Paus nupp).
English: Cimzia has not been studied in these patient populations.
Estonian: Cimzia toimeid nendel patsientidel ei ole uuritud.
English: • Once ava is placed firmly against your skin “When ready press > once” is shown.
Estonian: • Niipea kui “ava” on kindlalt vastu teie nahka, ilmub ekraanile “Kui olete valmis, vajutage > üks kord”.
English: Cimzia does not contain a fragment crystallisable (Fc) region, which is normally present in a complete antibody, and therefore does not fix complement or cause antibody-dependent cell-mediated cytotoxicity in vitro.
Estonian: Cimzia ei sisalda kristalliseeruvat (Fc) regiooni, mis on olemas täielikus antikehas, ja seetõttu ta ei fikseeri komplementi ega tekita antikehast-sõltuvat rakulist tsütotoksilisust in vitro.
English: The typical Cavg that produces half the maximum probability of ACR 20 response (EC50) was 17 µg/ml (95% CI: 10-23 µg/ml).
Estonian: Tüüpiline Cavg, mis tekitab 50% maksimaalsest ACR 20 ravivastuse tõenäosusest (EC50) oli 17 µg/ml (95% CI: 10-23 µg/ml).
English: • Do not remove the needle cap until ava instructs you to do so.
Estonian: •Ärge eemaldage nõela korki enne, kui „ava“ teil seda teha palub.
English: Interference with thrombin time (TT) and prothrombin time (PT) assays have not been observed.
Estonian: Reaktsioone trombiini aja (TT) ja protrombiini aja (PT) testidega ei ole leitud.
English: - Once the needle cap has been removed, you must give the injection within 5 minutes.
Estonian: Kui nõela kork on eemaldatud, peate süstima 5 minuti jooksul.
English: The solution is clear to opalescent, colourless to yellow.
Estonian: Lahus on selge kuni opalestseeruv ja värvitu kuni kollane.
English: **These events have been related to the class of TNF-antagonists.
Estonian: ** Need nähud on olnud seotud TNF-antagonistide ravimirühmaga.
English: Multiple doses of up to 800 mg subcutaneously and 20 mg/kg intravenously have been administered.
Estonian: Korduvalt manustati annuseid kuni 800 mg subkutaanselt ja 20 mg/kg intravenoosselt.
English: Wald p-values are quoted for the comparison of treatments using logistic regression with factors for treatment and region.
Estonian: Wald p-väärtused on määratud raviviiside võrdluseks kasutades logistilist regressiooni koos faktoritega ravi ja piirkonna jaoks.
English: Contact with natural rubber latex may cause severe allergic reactions in individuals sensitive to latex.
Estonian: Loodusliku kummilateksiga kokkupuutumine võib põhjustada lateksi suhtes tundlikel isikutel raskeid allergilisi reaktsioone.
English: - Keep the needle cap - you will need it to remove the used medication from ava later.
Estonian: Hoidke nõela kork alles - teil läheb seda pärast vaja, et eemaldada kasutatud ravim „ava-st“.
English: • Do not shake the medication.
Estonian: • Ärge raputage ravimit.
English: Heart failure - If you have mild HEART FAILURE and you are being treated with Cimzia, your heart failure status must be closely monitored by your doctor.
Estonian: Südamepuudulikkus - Kui teil on kerge SÜDAMEPUUDULIKKUS ja saate raviks Cimzia't, jälgib arst hoolikalt teie südamepuudulikkuse seisundit.
English: Distribution studies have demonstrated that placental and milk transfer of cTN3 PF to the foetal and neonatal circulation is negligible.
Estonian: Jaotuvus-uuringud on näidanud, et cTN3 PF ülekanne platsenta ja piima kaudu lootele ja vastsündinule on ebaoluline.
English: • Wash your hands thoroughly.
Estonian: • Peske hoolikalt käed.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu
Estonian: Täpne teave selle ravimpreparaadi kohta on Euroopa Ravimiameti kodulehel: http://www.ema.europa.eu/
English: In addition, since certolizumab pegol is a protein that is degraded in the gastrointestinal tract after oral administration, the absolute bioavailability is expected to be very low in a breastfed infant.
Estonian: Lisaks, kuna tsertolizumabpegool on valk, mis pärast suukaudset manustamist seedetraktis laguneb, on imetataval lapsel selle absoluutne biosaadavus eeldatavasti väga väike.
English: Almost all of these patients had received treatment with the immunosuppressants azathioprine and/or 6-mercaptopurine concomitantly with a TNF-antagonist at or prior to diagnosis.
Estonian: Peaaegu kõik need patsiendid on saanud immunosupressant-ravi asatiopriini ja/või 6merkaptopuriiniga koos TNF-antagonistidega enne diagnoosi saamist või diagnoosimise alguses.
English: Study AS0006, performed in subjects without radiographic signs of inflammation in the SI joints, confirmed the effect previously demonstrated in this subgroup in the AS001 study.
Estonian: AS0006 uuring, mis teostati katseisikutel, kellel ei esinenud radiograafilisi SI-liigeste põletiku tunnuseid, kinnitas AS001 uuringu selles alarühmas eelnevalt näidatud toimet.
English: • Push plunger head all the way down until the entire dose has been given and the plunger head is between the needle guard activation clips.
Estonian: • Vajutage kolb alla kuni kogu annus on süstitud ning kolvi pea asub nõelakaitset aktiveerivate klambrite vahel.
English: Not known multiple sclerosis*, Guillain-Barré syndrome*
Estonian: Teadmata Sclerosis multiplex*, Guillain-Barré sündroom*
English: Percentage response based upon number of subjects contributing data (n) to that endpoint and time point which may differ from N
Estonian: Ravivastuse protsent, mis põhineb andmeid kogutavatel patsientide arvul (n) vastavas lõpptulemi ja ajapunktis, võib erineda N-st
English: ASDAS-MI response was defined as an ASDAS reduction (improvement) ≥ 2.0 relative to baseline or as reaching the lowest possible score.
Estonian: ASDAS-MI vastust määratleti ASDAS vähenemisena (paranemine) ≥2,0 algväärtuse suhtes või madalaima võimaliku skoori saavutamisena.
English: • suicide attempt, mental impairment, delirium
Estonian: • enesetapukatsed, vaimsed häired, deliirium
English: Medication level indicator 3.
Estonian: Ravimi taseme idikaator 3.
English: There have been rare reports of other immunemediated conditions; the causal relationship to Cimzia is not known.
Estonian: Teatatud on teistest immuunvahendatud seisunditest, mille põhjuslik seos Cimzia'ga ei ole teada.
English: Patients receiving concomitant NSAIDs and conventional DMARDs were 72.6% and 70.2% respectively.
Estonian: Samaaegselt said NSAIDe ja DMARDe vastavalt 72,6% ja 70,2% patsientidest.
English: Patients were predominantly men (64%) and Caucasian (94%), with a mean age of 45.7 years (18 to 80 years); of these, 7.2% were ≥ 65 years of age.
Estonian: Patsiendid olid valdavalt mehed (64%) ja europiidsest rassist (94%), keskmise vanusega 45,7 aastat (18 kuni 80 aastat); neist 7,2% olid ≥ 65-aastased.
English: If the indicator is not at the bottom, contact your pharmacist.
Estonian: Kui indikaator ei ole põhjas, võtke ühendust apteekriga.
English: • serious skin rashes.
Estonian: • tõsised nahalööbed.
English: Before initiation of therapy with Cimzia, all patients must be evaluated for both active or inactive (latent) tuberculosis infection.
Estonian: Enne Cimzia-ravi alustamist tuleb kõiki patsiente uurida nii aktiivse kui ka inaktiivse (latentse) tuberkuloosi suhtes.
English: ASAS 40 was a secondary endpoint.
Estonian: ASAS 40 oli teisene tulemusnäitaja.
English: Children and adolescents Cimzia is not recommended for use in children and adolescents under the age of 18 years.
Estonian: Lapsed ja noorukid Cimzia't ei soovitata kasutada lastel ja alla 18-aastastel noorukitel.
English: Check the red medication level indicator is at the bottom of the cartridge - this shows you have had all of your injection.
Estonian: Kontrollige, et punane ravimi taseme indikaator oleks kolbampulli põhjas - see näitab, et kogu ravim süstiti.
English: The primary efficacy variable was the Ankylosing Spondylitis Disease Activity Score major improvement (ASDAS-MI) response at Week 52.
Estonian: Esmane efektiivsuse muutuja oli anküloseeriva spondüliidi toimeskaala peamise paranemise (ASDAS-MI) vastus 52. nädalal.
English: • The medication is to be used with the electromechanical injection device called “ava” which is provided separately.
Estonian: • Ravimit tuleb kasutada koos elektromehaanilise süsteseadmega, mille nimi on „ava“ ning mida müüakse eraldi.
English: This medicinal product is for single use only.
Estonian: Ravim on ühekordseks kasutamiseks.
English: The C-EARLY trial met its primary and key secondary endpoints.
Estonian: Kliiniline uuring C-EARLY täitis oma esmast lõpptulemit ja teisest tähtsaimat lõpptulemit.
English: Key results are presented in Table 9.
Estonian: Peamised tulemused on esitatud tabelis 9.
English: • Guillain-Barré syndrome*
Estonian: • Guillain-Barré sündroom*
English: Cimzia treated patients also had significant improvements in ACR 50 and 70 response rates.
Estonian: Cimzia ravirühmades esines ka olulist paranemist ACR 50 ja 70 ravivastuses.
English: Cimzia is used to reduce skin inflammation and other signs and symptoms of your disease.
Estonian: Cimzia't kasutatakse nahapõletiku ja teie haiguse teiste tunnuste ja sümptomite vähendamiseks.
English: Assessments on remission (DAS28(ESR) <2.6), Low Disease Activity (DAS28(ESR) ≤3.2) status, ACR50 and ACR 70 by visit demonstrated that Cimzia+MTX treatment led to faster and greater responses than PBO+MTX treatment.
Estonian: Remissiooni (DAS28(ESR) < 2,6), madala haigusaktiivsuse (DAS28(ESR) ≤ 3,2), ACR50 ja ACR 70 hindamine visiitidel näitas, et Cimzia+MTX-ravi tagas kiirema ja tõhusama ravivastuse kui PBO+MTX-ravi.
English: • after 12 weeks if you have rheumatoid arthritis, axial spondyloarthritis or psoriatic arthritis, or
Estonian: • 12 nädala möödumisel, kui teil on reumatoidartriit, aksiaalne spondüloartriit või psoriaatiline artriit,
English: Periodic skin examination is recommended, particularly for patients with risk factors for skin cancer.
Estonian: Seetõttu soovitatakse perioodilist naha seisundi jälgimist, eriti nahavähi riskiga patsientidele.
English: Table 1 Adverse reactions in clinical trials and postmarketing System Organ Class
Estonian: Tabel 1 Kliinilistes uuringutes ja turuletulekujärgselt esinenud kõrvaltoimed Organsüsteemi klass
English: Pharmacotherapeutic group: immunosuppressants, tumour necrosis factor alpha (TNFα) inhibitors, ATC code: L04AB05
Estonian: Farmakoterapeutiline rühm: immunosupressandid, tuumorinekroosifaktor alfa (TNF-alfa) inhibiitorid, ATC kood: L04AB05
English: Quality of life / Patient reported outcomes
Estonian: Elukvaliteet / patsientide teatatud andmed
English: - If you are at risk of or are a carrier of or have active HEPATITIS B VIRUS (HBV) infection, Cimzia may increase the risk of reactivation in people who carry this virus.
Estonian: - Kui teil on risk saada või teil on juba diagnoositud latentne või aktiivne B-HEPATIIT (HBV), võib Cimzia tõsta HBV aktiveerumise riski kandjatel.
English: This will include a thorough medical history, a chest X-ray and a tuberculin test.
Estonian: See hõlmab küsitlust põetud haiguste kohta, rindkere röntgenülesvõtet ja tuberkuliiniproovi.
English: Patients treated with Cimzia may receive vaccinations, except for live vaccines.
Estonian: Cimzia-ravi saavaid patsiente võib vaktsineerida, välja arvatud elusvaktsiinidega.
English: Tell your surgeon or dentist performing the procedure that you are having treatment with Cimzia by showing them your Patient Reminder Card.
Estonian: Rääkige oma kirurgile või hambaarstile, et te saate Cimzia-ravi ja näidake oma patsiendi meeldetuletuskaarti.
English: - If you have an infection or if you develop symptoms such as fever, wounds, tiredness or dental problems.
Estonian: - Kui teil on infektsioone või teil tekivad sümptomid, nagu palavik, haavad, väsimus või probleemid hammastega.
English: Creatine phosphokinase elevations
Estonian: Kreatiinfosfokinaasi tõusud
English: Cimzia may have a minor influence on your ability to drive and use machines.
Estonian: Cimzia'l võib olla vähene mõju teie võimele autot juhtida ja masinatega töötada.
English: • Do not use the medication if it has been dropped after taking it out of the pack.
Estonian: • Ärge kasutage ravimit, kui see on pärast pakendist väljavõtmist maha kukkunud.
English: Previous treatment with one TNF-antagonist was allowed and 20% of patients had prior TNF-antagonist exposure.
Estonian: Eelnev ravi ühe TNF-antagonistiga oli lubatud ning 20% patsientide koguarvust olid eelnevalt kasutanud TNF-antagonisti.
English: The injection begins when a first “click” is heard and the orange band at the bottom of the pre-filled pen disappears.
Estonian: Süstimine algab, kui kuulete esimest klõpsatust ning pen-süstli alaosas olev oranž riba kaob.
English: The difference from placebo tended to be greater in nr-axSpA than in the AS subpopulation which may be due to less chronic structural damage in nr-axSpA patients.
Estonian: Erinevus platseebost kaldus olema suurem mitteradiograafilise aksiaalse spondüloartriidi (nr-axSpA) puhul kui AS alarühmas, mis võib olla põhjustatud väiksemast kroonilisest struktuursest kahjustusest nr-axSpA patsientidel.
English: The additional following adverse reactions have been observed uncommonly with Cimzia in other indications: gastrointestinal stenosis and obstructions, general physical health deterioration, abortion spontaneous and azoospermia.
Estonian: Järgnevaid kõrvaltoimeid on aeg-ajalt leitud Cimzia kasutamisel teistel näidustustel: gastrointestinaalne stenoos ja obstruktsioonid, üldine füüsilise tervise halvenemine, spontaanne abort ja azoospermia.
English: Some of these reactions occurred after the first administration of Cimzia.
Estonian: Mõned neist reaktsioonidest on tekkinud pärast Cimzia esmakordset manustamist.
English: If you take Cimzia, your risk of getting lymphoma or other cancers may increase.
Estonian: Kui te kasutate Cimzia't, võib risk haigestuda lümfoomi või mõnda teise vähivormi suureneda.
English: If the seal(s) is missing or broken - do not use and contact your pharmacist.
Estonian: kui pitser(id) on puudu või katki - ärge kasutage ning võtke ühendust apteekriga.
English: Some of these reactions could occur after the first administration of Cimzia.
Estonian: Mõned neist reaktsioonidest võivad tekkida pärast Cimzia esmakordset manustamist.
English: • Place the orange skin sensor against the injection site where you are going to inject.
Estonian: •Asetage oranž nahasensor süstekoha vastu, kuhu kavatsete süstida.
English: Patients must have been intolerant to or had an inadequate response to at least one NSAID.
Estonian: Patsientidel pidi olema talumatus või ebapiisav ravivastus vähemalt ühe NSAID suhtes.
English: If your doctor determines that methotrexate is inappropriate, Cimzia can be given alone.
Estonian: Kui teie arst otsustab, et metotreksaat ei ole sobilik, võib Cimzia't kasutada üksi.
English: If you develop a fever that does not go away, bruise or bleed very easily or look very pale, call your doctor immediately.
Estonian: Kui teil tekib palavik, mis ei lähe üle, teil tekivad kergesti verejooksud ja verevalumid või olete väga kahvatu, võtke kohe ühendust oma arstiga.
English: Randomised, double-blind treatment regimen week 18 to 34
Estonian: Randomiseeritud, topeltpime annustamisrežiim nädalatel 18 kuni 34
English: Evaluation for treatment of signs and symptoms and inhibition of structural damage.
Estonian: Nähtude ja sümptomite ravi ning strukturaalsete kahjustuste inhibeerimise hindamine.
English: • Continue to hold the pre-filled pen in place firmly against the skin until a second “click” is heard and the viewing window turns orange.
Estonian: • Hoidke jätkuvalt pen-süstlit tugevasti paigal vastu nahka kuni kuulete teist klõpsatust ning näete, et vaateaken muutub oranžiks.
English: Hold the pre-filled pen straight (at a 90° degree angle) against the skin, that previously has been cleaned (the “injection site”).
Estonian: Hoidke pen-süstlit otse (90° nurga all) vastu nahapiirkonda, mis on eelnevalt puhastatud (“süstekoht”).
English: You might get an infection more easily while you are being treated with Cimzia, including serious, or in rare cases, life-threatening infections.
Estonian: Cimzia-ravi ajal võivad teil infektsioonid tekkida kergemini, kaasa arvatud rasked või harvadel juhtudel eluohtlikud infektsioonid.
English: • You will be instructed by your doctor or healthcare giver how to inject the medicine.
Estonian: • Teie arst või tervishoiutöötaja õpetab teile, kuidas ravimit süstida.
English: Rare odynophagia, hypermotility
Estonian: Odünofaagia, hüpermotiilsus
English: If this occurs, you should stop using Cimzia.
Estonian: Kui see tekib, peate Cimzia kasutamise lõpetama.
English: The dose-dispenser cartridge is also referred to as “medication”.
Estonian: Annusti kolbampulli nimetatakse ka „ravimiks“.
English: The pre-filled syringe with needle guard should only be used by healthcare professionals.
Estonian: Nõelakaitsega süstel on kasutamiseks ainult tervishoiutöötajatele.
English: *These events have been related to this class of medicines but the incidence with Cimzia is not known.
Estonian: * Neid kõrvaltoimeid on seostatud seda tüüpi ravimitega, kuid seos Cimzia'ga on teadmata
English: This effect has been observed with the PTT-Lupus Anticoagulant (LA) test and Standard Target Activated Partial Thromboplastin time (STA-PTT) Automate tests from Diagnostica Stago, and the HemosIL APTT-SP liquid and HemosIL lyophilised silica tests from Instrumentation Laboratories.
Estonian: Toimet on leitud Diagnostica Stago PTT-Lupus Anticoagulant (LA) testis ja Standard Target Activated Partial Thromboplastin time (STA-PTT) Automate testis ning Instrumentation Laboratories HemosIL APTT-SP liquid ja HemosIL lyophilized silica testis.
English: • Any unused product(s) or waste material should be disposed of in accordance with local requirements.
Estonian: • Kasutamata ravim (ravimid) või jäätmematerjal tuleb hävitada vastavalt kohalikele nõuetele.
English: Moderate to severe heart failure (NYHA classes III/IV) (see section 4.4).
Estonian: Mõõdukas kuni raske südamepuudulikkus (NYHA III/IV klass) (vt lõik 4.4).
English: These results were maintained over 52 weeks of treatment in DMARD-naïve subjects.
Estonian: Need tulemused säilisid 52 nädala jooksul DMARD-ravi mittesaanud patsientide ravis.
English: Week 52 p-values were < 0.001 for both mTSS and erosion score and ≤ 0.01 for JSN score.
Estonian: 52. nädal p-väärtused olid < 0,001 nii mTSS kui erosiooni skoori ja ≤ 0,01 mõlemas ajapunktis JSN skoori osas.
English: Rheumatoid arthritis Cimzia, in combination with methotrexate (MTX), is indicated for:
Estonian: Reumatoidartriit Cimzia kombinatsioonis metotreksaadiga (MTX) on näidustatud:
English: Patients must have been intolerant to or had an inadequate response to at least two NSAIDs.
Estonian: Patsientidel pidi olema talumatus või ebapiisav vastus vähemalt kahele MSPVA-le.
English: The improvement in BASMI linear score achieved at Week 24 was maintained through Week 204 for patients who remained in the study.
Estonian: 24-ndaks nädalaks saavutatud paranemine BASMI lineaarväärtuses säilis kuni 204. nädalani patsientidel, kes jätkasid uuringus.
English: No dose adjustment is required.
Estonian: Annuse kohaldamine ei ole vajalik.