FrancophonIA/ELRC3.0 huggingface dataset:
English: Since decreased concentrations of artemether, dihydroartemisinin, or lumefantrine may result in a decrease of antimalarial efficacy, caution is recommended when Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and artemether/lumefantrine tablets are co-administered.
Lithuanian: Kadangi dėl sumažėjusios artemetero, dihidroartemizinino arba lumefantrino koncentracijos gali sumažėti antimaliarinis veiksmingumas, reikia atsargiai kartu skirti
English: Morning Cmax: ↑ 24% (↑ 12 to ↑ 38) Evening Cmax: ↔
Lithuanian: Vakaro AUC: ↔ Ryto Cmax: ↑ 24 % (↑ 12 iki ↑ 38)
English: nausea
Lithuanian: Traukuliai
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and vigabatrin or gabapentin can be coadministered without dose adjustment.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka gali būti skiriama kartu su vigabatrinu arba gabapentinu nekoreguojant dozės.
English: Morning Cmin: ↑ 42% (↑ 9 to ↑ 86) Evening Cmin: ↑ 24% (↑ 3 to ↑ 50)
Lithuanian: Vakaro Cmax: ↔ Ryto Cmin: ↑ 42 % (↑ 9 iki ↑ 86)
English: Ritonavir/Emtricitabine
Lithuanian: Ritonaviras/emtricitabinas
English: Itraconazole/Efavirenz (200 mg b.i.d./600 mg q.d.)
Lithuanian: Itrakonazolas/efavirenzas (200 mg b.i.d.
English: DMPA/Tenofovir disoproxil
Lithuanian: DMPA/tenofoviras dizoproksilis
English: nephritis
Lithuanian: Natris
English: Simvastatin:
Lithuanian: Registruotojas:
English: Cmax: ↑ 25% (↑ 8 to ↑ 45) Cmin: ↔
Lithuanian: Cmax: ↑ 25 % (nuo ↑ 8 iki
English: Clarithromycin/Emtricitabine
Lithuanian: Klaritromicinas/emtricitabinas
English: ANTI-INFECTIVES HIV antivirals
Lithuanian: ANTIINFEKCINIAI ŽIV antivirusiniai vaistiniai preparatai Proteazių inhibitoriai
English: Maraviroc/Emtricitabine
Lithuanian: Maravirokas/emtricitabinas
English: Co-administration of Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka with sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/ voxilaprevir is not recommended (see section 4.4).
Lithuanian: Kartu vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka su sofosbuviru / velpatasviru arba sofosbuviru/velpatasviru/ voksilapreviru nerekomenduojama (žr.
English: Clarithromycin/Efavirenz (500 mg b.i.d./400 mg q.d.)
Lithuanian: Klaritromicinas/efavirenzas (500 mg b.i.d.
English: Pharmacokinetic studies have not been performed with efavirenz/emtricitabine/tenofovir disoproxil in infants and children under 18 years of age (see section 4.2).
Lithuanian: Nėra pakankamai duomenų apie vartojimą vaikams (jaunesniems kaip 18 metų amžiaus asmenims), todėl vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka vaikams nerekomenduojama (žr. 4.2 skyrių).
English: Tenofovir: AUC: ↔ Cmax: ↔
Lithuanian: Tenofoviro: AUC: ↔ Cmax: ↔
English: Rifampicin/Efavirenz (600 mg q.d./600 mg q.d.)
Lithuanian: Rifampicinas/efavirenzas (600 mg q.d.
English: Rifabutin/Tenofovir disoproxil
Lithuanian: Rifabutinas/tenofoviras dizoproksilis
English: Use of appropriate antihistamines and/or corticosteroids is recommended when Efavirenz/Emtricitabine/Tenofovir disoproxil Krka is restarted.
Lithuanian: Vėl pradėjus gerti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, rekomenduojama vartoti tinkamą antihistamininį vaistą ir (arba) kortikosteroidą.
English: Pravastatin/Emtricitabine
Lithuanian: Pravastatinas/emtricitabinas
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka, Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka should not be administered concomitantly with lamivudine (see section 4.4).
Lithuanian: Dėl lamivudino ir emtricitabino, Efavirenz/Emtricitabine/Tenofovir disoproxil Krka sudedamosios dalies emtricitabino panašumo Efavirenz/Emtricitabine/Tenofovir disoproxil Krka nereikėtų skirti kartu su lamivudinu (žr. 4.4 skyrių).
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and raltegravir can be co-administered without dose adjustment.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka ir raltegraviro galima skirti kartu nekoreguojant dozės.
English: Since Efavirenz/Emtricitabine/Tenofovir disoproxil Krka is a fixed-dose combination product, the dose of efavirenz cannot be altered; therefore, voriconazole and Efavirenz/Emtricitabine/Tenofovir disoproxil
Lithuanian: Kadangi Efavirenz/Emtricitabine/Tenofovir disoproxil Krka yra fiksuotos dozės sudėtinis vaistinis preparatas, efavirenzo dozė negali būti pakeista, todėl vorikonazolo kartu su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka skirti negalima (žr. 4.5 skyrių ir 1 lentelę).
English: Following multiple dose oral administration of emtricitabine to 20 HIV infected patients, steady-state Cmax was 1.8 ± 0.7 µg/ml (mean ± S.D.) (39%CV), steady-state Cmin was 0.09 ± 0.07 µg/ml (80%) and the AUC was 10.0 ± 3.1 µg•h/ml (31%) over a 24 hour dosing interval.
Lithuanian: N.) (39 % VK), Cmin - buvo 0,09 ± 0,07 µg/ml (80 %), AUC buvo 10,0 ± 3.1 µg•val/ml
English: Antimycobacterials Rifabutin/Efavirenz (300 mg q.d./600 mg q.d.)
Lithuanian: Rifabutinas/efavirenzas (300 mg q.d.
English: Methadone: AUC: ↔ Cmax: ↔ Cmin: ↔
Lithuanian: Metadono: AUC: ↔ Cmax: ↔ Cmin: ↔
English: Discontinuation of efavirenz/emtricitabine/tenofovir disoproxil therapy in patients co-infected with HIV and HBV may be associated with severe acute exacerbations of hepatitis (see section 4.4).
Lithuanian: Nutraukus ŽIV ir HBV infekuotų pacientų gydymą efavireno/emtricitabino/tenofoviro dizoproksilio gali smarkiai paūmėti hepatitas (žr.
English: The recommended dose of Efavirenz/Emtricitabine/Tenofovir disoproxil Krka is one tablet taken orally once daily.
Lithuanian: Rekomenduojama Efavirenz/Emtricitabine/Tenofovir disoproxil Krka dozė yra viena tabletė, kuri vartojama per burną vieną q.d.
English: Your doctor may conduct blood tests in order to check how well your liver is working or may switch you to another medicine.
Lithuanian: Tokiu atveju Jūsų gydytojas gali reguliariai tirti Jūsų kraują, kad patikrintų, ar gerai dirba Jūsų kepenys (žr.
English: Efavirenz/emtricitabine/tenofovir disoproxil is recommended for administration on an empty stomach since food may increase efavirenz exposure and may lead to an increase in the frequency of adverse reactions (see sections 4.4 and 4.8).
Lithuanian: Efavirenzo/emtricitabino/tenofoviro dizoproksilio rekomenduojama vartoti nevalgius, nes maistas gali padidinti efavirenzo ekspoziciją, o tai gali padidinti nepageidaujamų reakcijų dažnį (žr.
English: -0.5% (-3.2% to 2.2%)
Lithuanian: 98,9 % -0,5 % (nuo -3,2 % iki 2,2 %)
English: Simvastatin acid:
Lithuanian: - Pagalbinės medžiagos:
English: Posaconazole/Efavirenz (-/400 mg q.d.)
Lithuanian: Karbamazepinas/efavirenzas (400 mg q.d.
English: Cmax: ↓ 38%
Lithuanian: Cmin: ↓ 40%
English: N-monodesmethyl diltiazem: AUC: ↓ 37% (↓ 17 to ↓ 52) Cmax: ↓ 28% (↓ 7 to ↓ 44) Cmin: ↓ 37% (↓ 17 to ↓ 52)
Lithuanian: Nmonodesmetildiltiazem o: AUC: ↓ 37 % (↓ 17 iki ↓
English: Fosamprenavir/ritonavir/Emtricitab ine
Lithuanian: Darunaviras/ritonaviras/emtricitabi-nas
English: AUC: ↓ 34% (↓ 41 to ↓ 25) Cmax: ↓ 34% (↓ 41 to ↑ 25)
Lithuanian: AUC: ↓ 34 % (nuo ↓ 41 iki ↓ 25)
English: dizziness has been reported during treatment with efavirenz, emtricitabine and tenofovir disoproxil.
Lithuanian: Vis dėlto taikant gydymą efavirenzu, emtricitabinu ar tenofoviro dizoproksiliu pastebėtas svaigulys.
English: Simvastatin/Tenofovir disoproxil
Lithuanian: Rozuvastatinas/tenofoviras dizoproksilis
English: How to store Efavirenz/Emtricitabine/Tenofovir disoproxil Krka
Lithuanian: Kaip laikyti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka
English: ANNEX I
Lithuanian: Standart as
English: Artemether/Lumefantrine/Tenofovi r disoproxil
Lithuanian: Artemeteras / lumefantrinas / tenofoviro dizoproksilis
English: Norelgestromin (active metabolite): AUC: ↓ 64% (↓ 62 to ↓ 67) Cmax: ↓ 46% (↓ 39 to ↓ 52) Cmin: ↓ 82% (↓ 79 to ↓ 85)
Lithuanian: Norelgestromino (veiklusis metabolitas): AUC: ↓ 64 % (↓ 62 iki
English: saquinavir/ritonavir and Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka is not recommended.
Lithuanian: Sakvinavirą ir ritonavirą vartoti kartu su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka nerekomenduojama.
English: Efavirenz/emtricitabine/tenofovir disoproxil should be administered with caution to patients with mild hepatic impairment (see sections 4.3 and 4.4).
Lithuanian: Pacientams, sergantiems lengvu kepenų veiklos sutrikimu, efavireno/emtricitabino/tenofoviro dizoproksilio reikia skirti atsargiai (žr. 4.3 ir 4.4 skyrius).
English: Efavirenz: AUC: ↔ Cmax: ↔
Lithuanian: Efavirenzas: AUC: ↔ Cmax: ↔
English: Psychiatric disorders: Common depression (severe in 3, anxiety 3, abnormal dreams 3, insomnia abnormal dreams, insomnia
Lithuanian: Psichikos sutrikimai: Dažni depresija (1,6 % sunki) nerimas
English: It is recommended that Efavirenz/Emtricitabine/Tenofovir disoproxil Krka be taken on an empty stomach since food may increase efavirenz exposure and may lead to an increase in the frequency of adverse reactions (see sections 4.4 and 4.8).
Lithuanian: Rekomenduojama Efavirenz/Emtricitabine/Tenofovir disoproxil Krka vartoti nevalgius, nes maistas gali padidinti efavirenzo ekspoziciją, todėl gali padidėti nepageidaujamų reakcijų dažnumas (žr.
English: Fluoxetine/Emtricitabine
Lithuanian: Fluoksetinas/emtricitabinas
English: Two subjects with confirmed virologic rebound developed NNRTI resistance-associated substitutions to efavirenz including K103N, V106V/I/M and Y188Y/C reverse transcriptase substitutions at week 240 (96 weeks on efavirenz/emtricitabine/tenofovir disoproxil) and week 204 (60 weeks on efavirenz/emtricitabine/tenofovir disoproxil).
Lithuanian: 240 savaitę (96 savaites vartojant efavirenzo/emtricitabino/tenofoviro dizoproksilio) ir 204 savaitę (60 savaičių vartojant efavirenzo/emtricitabino/tenofoviro dizoproksilio) dviem pacientams, kuriems buvo patvirtintas virusologinis atkrytis, išsivystė su atsparumu NNATI susiję efavirenzo pakaitai, įskaitant K103N, V106V/I/M ir Y188Y/C atvirkštinės transkriptazės pakaitus.
English: What you need to know before you take Efavirenz/Emtricitabine/Tenofovir disoproxil
Lithuanian: Kas žinotina prieš vartojant Efavirenz/Emtricitabine/Tenofovir disoproxil Krka
English: Tenofovir: AUC: ↔ Cmax: ↔ Cmin: ↔
Lithuanian: Tenofoviro: AUC: ↔ Cmax: ↔ Cmin: ↔
English: Insufficient data are available to make a dosing recommendation for atazanavir/ritonavir in combination with efavirenz/emtricitabine/tenofovir disoproxil.
Lithuanian: Parengti dozavimo rekomendacijas lopinaviro ir ritonaviro deriniui su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka duomenų nepakanka.
English: Diltiazem/Tenofovir disoproxil
Lithuanian: Efavirenzum/emtricitabinum/tenofovirum disoproxilum
English: Rare renal failure (acute and chronic), acute tubular necrosis,
Lithuanian: Reti inkstų nepakankamumas (ūminis ir lėtinis), ūmi kanalėlių nekrozė, nefritas (įskaitant ūminį intersticinį nefritą) nefrogeninis necukrinis diabetas
English: Mild-to-moderate rash has been reported with the individual components of efavirenz/emtricitabine/tenofovir disoproxil.
Lithuanian: Pastebėtas lengvas ar vidutinio sunkumo išbėrimas, susijęs su atskiromis efavireno/emtricitabino/tenofoviro dizoproksilio sudedamosiomis dalimis.
English: If the patient vomits more than 1 hour after taking Efavirenz/Emtricitabine/Tenofovir disoproxil Krka he/she does not need to take another dose.
Lithuanian: laikotarpiu vemia, reikia išgerti kitą tabletę. Jei pacientas, išgėręs Efavirenz/Emtricitabine/Tenofovir disoproxil Krka tabletę, vemia vėliau nei po 1 val., jam ar jai kitos dozės vartoti nereikia.
English: Atorvastatin/Emtricitabine
Lithuanian: Atorvastatinas/emtricitabinas
English: Tacrolimus: AUC: ↔ Cmax: ↔ C24h: ↔
Lithuanian: Takrolimuzas: AUC: ↔ Cmax: ↔ C24: ↔
English: Paroxetine: AUC: ↔ Cmax: ↔ Cmin: ↔
Lithuanian: Paroksetino: AUC: ↔ Cmax: ↔ Cmin: ↔
English: Rifampicin/Tenofovir disoproxil (600 mg q.d./245 mg q.d.)
Lithuanian: Rifampicinas/tenofoviras dizoproksilis (600 mg q.d.
English: Insufficient data are available to make a dosing recommendation for indinavir when dosed with Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka.
Lithuanian: Parengti dozavimo rekomendacijas indinaviro deriniui su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka duomenų nepakanka.
English: If Efavirenz/Emtricitabine /Tenofovir disoproxil Krka is used with nephrotoxic medicinal products, renal function should be closely monitored according to the recommended schedule.
Lithuanian: - Reikia vengti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka vartoti kartu su arba netrukus po nefrotoksinių vaistinių preparatų vartojimo. Jei Efavirenz/Emtricitabine/Tenofovir disoproxil Krka vartojamas su nefrotoksiniais vaistiniais preparatais, būtina pagal rekomenduojamą tvarkaraštį atidžiai stebėti inkstų funkciją.
English: Efavirenz: no clinically significant interaction.
Lithuanian: kliniškai reikšmingos sąveikos nėra.
English: AUC: ↓ 43% (↓ 7 to ↓ 65) Cmax: ↔
Lithuanian: Cmax: ↓ 64 % (↓ 57 iki ↓
English: Atazanavir/ritonavir/Efavirenz (400 mg q.d./200 mg q.d./600 mg q.d., all administered with food)
Lithuanian: Atazanaviras/ritonaviras/efavirenzas (400 mg q.d, 200 mg q.d ir 600 mg q.d, visi skiriami valgio metu)
English: Maraviroc/Tenofovir disoproxil (300 mg b.i.d./245 mg q.d.)
Lithuanian: Maravirokas/tenofoviras dizoproksilis (300 mg b.i.d.
English: Simvastatin/Emtricitabine
Lithuanian: Simvastatinas/emtricitabinas
English: Etonogestrel/Tenofovir disoproxil Interaction not studied.
Lithuanian: Valproinė rūgštis/tenofoviras dizoproksilis Sąveika netirta.
English: As Efavirenz/Emtricitabine/Tenofovir disoproxil Krka may cause renal damage, monitoring of renal function is recommended (see sections 4.4 and 4.8 Summary of the safety profile).
Lithuanian: Kadangi Efavirenz/Emtricitabine/Tenofovir disoproxil Krka gali sukelti inkstų pažeidimą, rekomenduojama stebėti inkstų funkcionavimą (žr.
English: AUC: ↓ 54%
Lithuanian: Buprenorfino: AUC: ↓ 50 %
English: AUC: ↓ 69% (↓ 62 to ↓ 73) Cmax: ↓ 76% (↓ 63 to ↓ 79)
Lithuanian: Simvastatino: AUC: ↓ 69 % (↓ 62 iki ↓
English: Do not breast-feed during treatment with Efavirenz/Emtricitabine/Tenofovir disoproxil Krka.
Lithuanian: Nepasitarę su savo gydytoju nenustokite vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka.
English: If you forget to take Efavirenz/Emtricitabine/Tenofovir disoproxil Krka
Lithuanian: Pamiršus pavartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka
English: Paroxetine/Efavirenz (20 mg q.d./600 mg q.d.)
Lithuanian: Paroksetinas/efavirenzas (20 mg q.d.
English: Pravastatin/Efavirenz (40 mg q.d./600 mg q.d.)
Lithuanian: Pravastatinas/efavirenzas (40 mg q.d.
English: Voriconazole/Efavirenz (200 mg b.i.d./400 mg q.d.)
Lithuanian: Vorikonazolas/efavirenzas (200 mg b.i.d.
English: If creatinine clearance is confirmed as < 50 ml/min or serum phosphate decreases to < 1.0 mg/dl then Efavirenz/Emtricitabine /Tenofovir disoproxil Krka therapy should be interrupted.
Lithuanian: Pacientams, kuriems yra vidutinio sunkumo ar sunkus inkstų veiklos sutrikimas (kreatinino klirensas < 50 ml/min), Efavirenz/Emtricitabine/Tenofovir disoproxil Krka skirti nerekomenduojama.
English: Cases of acute renal failure after initiation of high dose or multiple non-steroidal anti-inflammatory drugs (NSAIDs) have been reported in patients treated with tenofovir disoproxil and with risk factors for renal dysfunction.
Lithuanian: Pradėjus skirti didelių dozių arba kartotinai vartojamus nesteroidinius vaistus nuo uždegimo (NVNU) pacientams, kurie buvo gydomi tenofoviro dizoproksiliu ir kuriems yra inkstų veiklos sutrikimo rizikos faktorių, nustatyta ūminio inkstų nepakankamumo atvejai. Jei Efavirenz/Emtricitabine/Tenofovir disoproxil Krka skiriamas kartu su NVNU, reikia tinkamai stebėti inkstų veiklą.
English: Lopinavir/ritonavir/Tenofovir disoproxil (400 mg b.i.d./100 mg b.i.d./245 mg q.d.)
Lithuanian: Darunaviras/ritonaviras/tenofoviras dizoproksilis (300 mg b.i.d.* / 100 mg b.i.
English: ANTICOAGULANTS Warfarin/Efavirenz Acenocoumarol/Efavirenz
Lithuanian: ANTIKOAGULIANTAI Varfarinas/efavirenzas Acenokumarolis/efavirenzas
English: Atazanavir/ritonavir/Efavirenz (400 mg q.d./100 mg q.d./600 mg q.d., all administered with food)
Lithuanian: Atazanaviras/ritonaviras/efavirenzas (400 mg q.d, 100 mg q.d ir 600 mg q.d, visi skiriami valgio metu)
English: AUC: ↓ 31% (↓ 8 to ↓ 47) Cmin: ↓ 40%
Lithuanian: Indinaviro: AUC: ↓ 31 % (↓ 8 iki
English: Ginkgo biloba extracts (herbal preparation).
Lithuanian: - Ginkmedžio lapų ekstraktas (augalinis preparatas).
English: Since no dose recommendation can be made for itraconazole
Lithuanian: Kadangi itrakonazolo dozės vartojant kartu su
English: Emtricitabine: AUC: ↔ Cmax: ↔ C24h: ↔
Lithuanian: Emtricitabinas: AUC: ↔ Cmax: ↔ C24: ↔
English: Due to the similarity between lamivudine and emtricitabine, a component of
Lithuanian: Kadangi fluoksetino ir paroksetino metabolizmo pobūdis panašus, t.y.
English: Vigabatrin/Efavirenz
Lithuanian: Vigabatrinas/efavirenzas
English: Fosamprenavir/ritonavir/Efavirenz (700 mg b.i.d./100 mg b.i.d./600 mg q.d.)
Lithuanian: Fozamprenaviras/ritonaviras/efavirenzas (700 mg b.i.d.
English: Paroxetine/Emtricitabine
Lithuanian: Paroksetinas/emtricitabinas
English: If Efavirenz/Emtricitabine/Tenofovir disoproxil Krka is stopped, speak to your doctor before you restart taking Efavirenz/Emtricitabine/Tenofovir disoproxil Krka tablets.
Lithuanian: Gydymo Efavirenz/Emtricitabine/Tenofovir disoproxil Krka sustabdymas gali rimtai pakenkti Jūsų atsakui į būsimą gydymą. Jei nebevartojote Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, prieš pradėdami vėl vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka tabletes pasakykite savo gydytojui. Jeigu turite problemų arba reikia koreguoti dozę, Jūsų gydytojas atsižvelgs į tai skirdamas atskiras Efavirenz/Emtricitabine/Tenofovir disoproxil Krka sudedamąsias dalis.
English: Valproic acid/Efavirenz (250 mg b.i.d./600 mg q.d.)
Lithuanian: Valproinė rūgštis/efavirenzas (250 mg b.i.d.
English: Swallow Efavirenz/Emtricitabine/Tenofovir disoproxil Krka whole with water.
Lithuanian: Nurykite Efavirenz/Emtricitabine/Tenofovir disoproxil Krka tabletę nesukramtę, užgerdami vandeniu.
English: Cmin: ↑ 51% (↑ 37 to ↑ 66)
Lithuanian: Cmin: ↑ 121% (nuo ↑ 100 iki ↑ 143)
English: Pointes, consider alternatives to efavirenz/emtricitabine/tenofovir disoproxil.
Lithuanian: 3 skyrių, Nustojus vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka).
English: Protease inhibitors Atazanavir/ritonavir/Tenofovir disoproxil (300 mg q.d./100 mg q.d./245 mg q.d.)
Lithuanian: Atazanaviras/ritonaviras/tenofoviras dizoproksilis (300 mg per parą, 100 mg q.d.
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and paroxetine can be co-administered without dose adjustment.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka ir sofosbuviras gali būti vartojami kartu, nekoreguojant dozės.
English: As a fixed combination, Efavirenz/Emtricitabine/Tenofovir disoproxil Krka should not be administered concomitantly with other medicinal products containing the components, emtricitabine or tenofovir disoproxil as. Efavirenz/Emtricitabine/Tenofovir disoproxil Krka should not be co administered with products containing efavirenz unless needed for dose adjustment e.g. with rifampicin (see section 4.2).
Lithuanian: Reikia vengti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka vartoti kartu su arba netrukus po nefrotoksinių vaistinių preparatų vartojimo. Jei Efavirenz/Emtricitabine/Tenofovir disoproxil Krka ir nefrotoksinių vaistinių preparatų (pvz.
English: Co-administration of ritonavir at doses of 600 mg and Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka is not recommended.
Lithuanian: 600 mg ritonaviro dozes vartoti kartu su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka nerekomenduojama.
English: 3, suicide ideation
Lithuanian: 3, neįprasti sapnai
English: AUC: ↓ 58% (↓ 39 to ↓ 68) Cmax: ↓ 51% (↓ 32 to ↓ 58)
Lithuanian: Cmax: ↓ 51 % (↓ 32 iki
English: Fluoxetine/Tenofovir disoproxil
Lithuanian: Fluoksetinas/tenofoviras dizoproksilis
English: What Efavirenz/Emtricitabine/Tenofovir disoproxil Krka looks like and contents of the pack
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka išvaizda ir kiekis pakuotėje
English: Diltiazem or similar medicines (called calcium channel blockers): When you start taking Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, your doctor may need to adjust your dose of the calcium channel blocker.
Lithuanian: Kai Jūs pradėsite vartoti Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, gydytojui gali reikėti koreguoti Jūsų kalcio kanalų blokatorių dozę.
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka is a fixeddose Combination product, the dose of efavirenz cannot be altered; therefore, voriconazole and Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka must not be coadministered.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka yra fiksuotos dozės vaistinis preparatas, efavirenzo dozės negalima pakeisti, todėl vorikonazolą kartu su
English: Fluoxetine/Efavirenz
Lithuanian: Fluoksetinas/efavirenzas
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and fluoxetine can be co-administered without dose adjustment.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka ir fluoksetinas gali būti skiriami kartu.
English: Simvastatin/Efavirenz (40 mg q.d./600 mg q.d.)
Lithuanian: Simvastatinas/efavirenzas (40 mg q.d.
English: Paroxetine/Tenofovir disoproxil
Lithuanian: Bupropionas/tenofoviras dizoproksilis
English: Common pruritus vesiculobullous rash, pustular rash,
Lithuanian: Tai klaritromicinas, rifabutinas ir rifampicinas.
English: severe disturbances of electrolyte balance e.g. hypokalemia or hypomagnesemia.
Lithuanian: , yra hipokalemija arba hipomagnezemija).
English: Renal failure, renal impairment, elevated creatinine, hypophosphataemia and proximal tubulopathy (including Fanconi syndrome) have been reported with the use of tenofovir disoproxil in clinical practice (see section 4.8).
Lithuanian: Inkstų ir šlapimo takų sutrikimai: Nedažni padidėjęs kreatinino kiekis, proteinurija, proksimalinė inkstų tubulopatija, įskaitant Fanconi sindromą
English: AUC12h: ↓ 45% (↓ 38 to ↓ 51) Cmax: ↓ 51% (↓ 37 to ↓ 62)
Lithuanian: Cmax: ↓ 51 % (↓ 37 iki
English: AUC: ↓ 40% (↓ 26 to ↓ 57) Cmax: ↓ 18% (↓ 59 to ↑ 12)
Lithuanian: Dezacetildiltiazemo: AUC: ↓ 75 % (↓ 59 iki ↓
English: You may require blood tests to check how your liver is working for 4 months after stopping treatment.
Lithuanian: 4 mėnesius po gydymo nutraukimo reguliariai atlikti kraujo tyrimus, norint patikrinti, kaip veikia Jūsų kepenys.
English: Efavirenz: AUC: ↔ Cmax: ↔ Cmin: ↔
Lithuanian: Efavirenzas: AUC: ↔ Cmax: ↔ Cmin: ↔
English: Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka and fosamprenavir/ritonavir can be co-administered without dose adjustment.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka ir fozamprenavirą / ritonavirą galima skirti kartu nekoreguojant dozės.
English: Dose adjustments of diltiazem when coadministered with Efavirenz/Emtricitabine/Tenofovi r disoproxil Krka should be guided by clinical response (refer to the Summary of Product Characteristics for diltiazem).
Lithuanian: Diltiazemo, vartojamo kartu su Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, dozę koreguoti reikia pagal klinikinį atsaką (žr.
English: You must not take Efavirenz/Emtricitabine/Tenofovir disoproxil Krka with certain medicines.
Lithuanian: Gydymosi Efavirenz/Emtricitabine/Tenofovir disoproxil Krka metu nežindykite.
English: Sertraline/Tenofovir disoproxil
Lithuanian: Sertralinas/tenofoviras dizoproksilis
English: Valproic acid/Emtricitabine
Lithuanian: Valproinė rūgštis/emtricitabinas
English: Gastrointestinal disorders: Very common diarrhoea, nausea diarrhoea,
Lithuanian: Nedažni veido paraudimas Virškinimo trakto sutrikimai: Labai dažni viduriavimas, pykinimas viduriavimas, vėmimas, pykinimas
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka is not recommended if you have moderate to severe kidney disease.
Lithuanian: Efavirenz/Emtricitabine/Tenofovir disoproxil Krka, yra didesnė inkstų ligų rizika.
English: AUC: ↓ 39% (↓ 30 to ↓ 46) Cmax: ↓ 26% (↓ 15 to ↓ 35)
Lithuanian: Efavirenzo: AUC: ↓ 26 % (↓ 15 iki ↓