FrancophonIA/ELRC3.0 huggingface dataset:
English: All patients should be advised to report symptoms of visual impairment, such as changes in visual acuity, changes in colour vision, blurred vision, or visual field defect.
Slovenian: Vsem bolnikom je treba svetovati, da morajo zdravnika obvestiti o motnjah vida, kot so spremembe v ostrini vida, spremembe barvnega zaznavanja, zamegljen vid ali okvara vidnega polja.
English: Do not take any medicine to treat your diarrhoea without first checking with your doctor.
Slovenian: Ne vzemite nobenega zdravila za zdravljenje driske, ne da bi se prej posvetovali z zdravnikom.
English: Sivextro may have a minor influence on the ability to drive and use machines as it may cause dizziness, fatigue or, uncommonly, somnolence (see section 4.8).
Slovenian: Zdravilo Sivextro ima lahko blag vpliv na sposobnost vožnje in upravljanja strojev, saj lahko povzroči omotico, utrujenost ali, občasno, zaspanost (glejte poglavje 4.8).
English: The elimination half-life of tedizolid is approximately 12 hours and the intravenous clearance is 6-7 L/h.
Slovenian: Razpolovni čas izločanja tedizolida je približno 12 ur, očistek po intravenskem odmerku pa je 6-7 l/h.
English: It must not be administered as an intravenous bolus.
Slovenian: Ne sme se dajati v obliki intravenskega bolusa.
English: The safety and efficacy of tedizolid phosphate in children and adolescents below 18 years of age have not yet been established.
Slovenian: Varnost in učinkovitost tedizolid fosfata pri otrocih in mladostnikih, starih manj kot 18 let, še nista bili dokazani.
English: What Sivextro is and what it is used for
Slovenian: Kaj je zdravilo Sivextro in za kaj ga uporabljamo
English: • any problems with your eyesight such as blurred vision, changes in colour vision, difficulty in seeing detail or if your field of vision becomes restricted.
Slovenian: • kakršne koli težave z vidom, kot so zamegljen vid, spremembe barvnega vida, težave pri videnju podrobnosti ali če se vaše vidno polje zmanjša.
English: The resulting solution is a clear colourless or light-yellow solution and should be administered over approximately 1 hour.
Slovenian: Nastala raztopina je bistra, brezbarvna ali svetlo rumena in se mora aplicirati približno 1 uro.
English: The average binding of tedizolid to human plasma proteins is approximately 70-90%.
Slovenian: Povprečna vezava tedizolida na plazemske beljakovine pri človeku sega od približno 70 do 90 %.
English: In the event of overdose, Sivextro should be discontinued and general supportive treatment given.
Slovenian: V primeru prevelikega odmerjanja je treba uporabo zdravila Sivextro prekiniti in bolniku nuditi splošno podporno zdravljenje.
English: 3) or severely immunocompromised patients.
Slovenian: 3) ali zelo oslabljenim imunskim sistemom.
English: Patients with neutropenia
Slovenian: Bolniki z nevtropenijo
English: This study used sensitive morphologic evaluation of perfusion-fixed peripheral and central nervous system tissue.
Slovenian: V tej študiji so uporabili občutljivo morfološko oceno tkiv perifernega in centralnega živčevja, fiksiranih s perfuzijo.
English: Sivextro must not be mixed with other medicinal products.
Slovenian: Zdravilo Sivextro se ne sme mešati z drugimi zdravili.
English: Do not use this medicine if you notice any particles or the solution is cloudy.
Slovenian: Ne uporabljajte tega zdravila, če v raztopini opazite kakršne koli delce ali če je motna.
English: CDAD must be considered in all patients who present with severe diarrhoea following antibiotic use.
Slovenian: Možnost pojava CDAD je treba upoštevati pri vseh bolnikih, pri katerih po uporabi antibiotikov nastopi huda diareja.
English: Tell your doctor straight away if you suffer from any of the following while taking Sivextro:
Slovenian: Takoj povejte zdravniku, če imate med jemanjem zdravila Sivextro kaj od naslednjega:
English: This is when antibiotics cannot stop the growth of bacteria and treat your infection.
Slovenian: Takrat antibiotiki ne morejo ustaviti razraščanja bakterij in pozdraviti okužbe.
English: Only the pharmacokinetic profile of tedizolid is discussed in this section.
Slovenian: V tem poglavju je opisan samo farmakokinetični profil tedizolida.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from tedizolid phosphate therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Slovenian: Odločiti se je treba med prenehanjem dojenja in prenehanjem/prekinitvijo zdravljenja s tedizolid fosfatom, pri čemer je treba pretehtati prednosti dojenja za otroka in prednosti zdravljenja za mater.
English: OUTER CARTON (VIAL)
Slovenian: ZUNANJA ŠKATLA (VIALA)
English: Administration of Sivextro with tyramine-rich foods (i.e., containing tyramine levels of approximately 100 mg) would not be expected to elicit a pressor response.
Slovenian: Pri uporabi zdravila Sivextro sočasno s tiraminom bogatimi živili (tj. vsebnost tiramina približno 100 mg) sprožitve presornega odziva ni mogoče pričakovati.
English: Organisms
Slovenian: Organizmi
English: Any unused medicine or waste material, including materials used for reconstitution, dilution and administration, should be disposed of in accordance with local requirements.
Slovenian: Neuporabljeno zdravilo ali odpadni material, vključno z materiali, ki se uporabljajo za rekonstitucijo, redčenje in dajanje, zavrzite v skladu z lokalnimi predpisi.
English: It is available in packs containing 1 or 6 vials.
Slovenian: Zdravilo je na voljo v pakiranjih, ki vsebujejo po 1- ali 6-vial.
English: Warnings and precautions Your doctor will have decided if Sivextro is suitable to treat your infection.
Slovenian: Opozorila in previdnostni ukrepi Zdravnik bo presodil, ali je zdravilo Sivextro primerno za zdravljenje vaše okužbe.
English: Clinical efficacy has not been established against the following pathogens although in vitro studies suggest that they would be susceptible to tedizolid in the absence of acquired mechanisms of resistance:
Slovenian: Klinična učinkovitost proti naslednjim patogenom ni bila dokazana, čeprav študije in vitro nakazujejo, da so občutljivi za tedizolid, če nimajo pridobljenih mehanizmov odpornosti:
English: • methotrexate (used to treat cancer, rheumatoid arthritis or psoriasis)
Slovenian: • metotreksat (za zdravljenje raka, revmatoidnega artritisa ali psoriaze)
English: Sivextro can interfere with the effects of these medicines.
Slovenian: Zdravilo Sivextro lahko moti učinke teh zdravil.
English: The safety and efficacy of tedizolid phosphate in patients with neutropenia (neutrophil counts <1,000 cells/mm
Slovenian: Varnost in učinkovitost tedizolid fosfata pri bolnikih z nevtropenijo (število nevtrofilcev < 1.000 celic/mm
English: • Sleepiness, abnormal sleep pattern, difficulty sleeping, nightmares (unpleasant/disturbing dreams)
Slovenian: • zaspanost, nenormalen vzorec spanja, težave s spanjem, nočne more (neprijetne/moteče sanje)
English: If not, the reconstituted and diluted solution should be stored at room temperature or in a refrigerator at 2°C to 8°C, and administered within 24 hours after reconstitution.
Slovenian: Če se ne uporabi takoj, se mora rekonstituirana in razredčena raztopina hraniti pri sobni temperaturi ali v hladilniku pri temperaturi od 2 °C do 8 °C ter uporabiti v 24 urah po rekonstituciji.
English: Driving and using machines Do not drive or use machines if you feel dizzy or tired after taking this medicine.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Ne vozite in ne uporabljajte strojev, če ste po uporabi tega zdravila omotični ali utrujeni.
English: Tedizolid, generated from tedizolid phosphate after metabolic activation (in vitro and in vivo), was also tested for genotoxicity.
Slovenian: Tedizolid, ki nastane iz tedizolid fosfata po aktivaciji presnove (in vitro in vivo), je bil preskušen tudi glede genotoksičnosti.
English: Studies in mice and rats showed developmental effects (see section 5.3).
Slovenian: Študije na miših in podganah so pokazale učinke na razvoj (glejte poglavje 5.3).
English: • statins such as pitavastatin, rosuvastatin (used to lower blood cholesterol)
Slovenian: • statine, kot sta pitavastatin, rosuvastatin (za zniževanje ravni holesterola v krvi).
English: It belongs to a group of medicines called “oxazolidinones”.
Slovenian: Spada v skupino zdravil, ki jih imenujemo "oksazolidinoni".
English: • sumatriptan, zolmitriptan (used to treat migraine)
Slovenian: • sumatriptan, zolmitriptan (za zdravljenje migrene)
English: It is used to treat adults with infections of the skin and tissues below the skin.
Slovenian: Uporablja se za zdravljenje odraslih z okužbami kože in mehkih tkiv.
English: Membrane transporters
Slovenian: Membranski prenašalci
English: Appropriate supportive measures, antibiotic treatment of C. difficile, and surgical evaluation should be considered.
Slovenian: Razmisliti je treba tudi o ustreznih podpornih ukrepih, zdravljenju okužbe s C. difficile z antibiotiki in kirurški oceni.
English: In such cases, prompt evaluation is recommended with referral to an ophthalmologist as necessary.
Slovenian: V teh primerih se priporoča takojšnja ocena stanja in po potrebi napotitev k oftalmologu.
English: Tedizolid phosphate film-coated tablets or powder for concentrate for solution for infusion may be used as initial therapy.
Slovenian: Tedizolid fosfat v obliki filmsko obloženih tablet ali praška za koncentrat za raztopino za infundiranje se lahko uporabi za začetno zdravljenje.
English: • Blurred vision, ‘floaters' (small shapes seen floating in the field of vision)
Slovenian: • zamegljen vid, "motnjave" v očesu (majhne oblike, ki lebdijo v vidnem polju)
English: Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
Slovenian: Potrebna je natančna anamneza, saj so o pojavu CDAD poročali v obdobju več kot dveh mesecev po uporabi antibiotikov.
English: Adverse reactions are classified by preferred term and System Organ Class, and by frequency.
Slovenian: Neželeni učinki so razvrščeni po priporočenih izrazih, organskih sistemih in pogostnosti.
English: Shaking or rapid movement should be avoided as it may cause foaming.
Slovenian: Tresenju ali hitrim gibom se je treba izogibati, ker lahko povzročijo penjenje.
English: If CDAD is suspected or confirmed, tedizolid phosphate and, if possible, other antibacterial agents not directed against C. difficile should be discontinued and adequate therapeutic measures should be initiated immediately.
Slovenian: V primeru suma ali potrditve CDAD je treba prekiniti uporabo tedizolid fosfata in če je mogoče drugih antibiotikov, ki niso usmerjeni proti C. difficile, ter nemudoma uvesti ustrezne terapevtske ukrepe.
English: The impact of gender on the pharmacokinetics of tedizolid phosphate was evaluated in healthy males and females in clinical studies and in a population pharmacokinetics analysis.
Slovenian: Vpliv spola na farmakokinetiko tedizolid fosfata so ocenili pri zdravih moških in ženskah v kliničnih študijah in populacijskih farmakokinetičnih analizah.
English: The most commonly observed mutations in staphylococci and enterococci that result in oxazolidinone resistance are in one or more copies of the 23S rRNA genes (G2576U and T2500A).
Slovenian: Najpogosteje opažene mutacije pri stafilokokih in enterokokih, ki povzročajo odpornost na oksazolidinone, so v eni ali več kopijah genov 23S rRNA (G2576U in T2500A).
English: EU/1/15/991/002 1 vial EU/1/15/991/003 6 vials
Slovenian: EU/1/15/991/002 1 viala EU/1/15/991/003 6 vial
English: No meaningful changes in blood pressure or heart rate with pseudoephedrine were observed in the healthy volunteers, and no clinically relevant increase in tyramine sensitivity was observed.
Slovenian: Opazili niso ne pomembnih sprememb krvnega tlaka ali srčnega utripa pri uporabi psevdoefedrina pri zdravih prostovoljcih ne klinično pomembnega povečanja občutljivosti za tiramin.
English: Film-coated tablet 6 x 1 film-coated tablets
Slovenian: filmsko obložene tablete 6 x 1 filmsko obložena tableta
English: • amitriptyline, citalopram, clomipramine, dosulepin, doxepin, fluoxetine, fluvoxamine,
Slovenian: • amitriptilin, citalopram, klomipramin, dosulepin, doksepin, fluoksetin, fluvoksamin, imipramin,
English: Do not use Lactated Ringer's Injection or Hartmann's Solution.
Slovenian: Ne uporabljajte raztopine Ringerjevega laktata za injiciranje ali Hartmannove raztopine.
English: The powder will be reconstituted in the vial with 4 mL of water for injections.
Slovenian: Prašek se rekonstituira v viali s 4 ml vode za injekcije.
English: If the same intravenous line is used for sequential infusion of several different medicinal products, the line should be flushed before and after infusion with 0.9% sodium chloride.
Slovenian: Če se za zaporedno infundiranje več različnih zdravil uporabi ista intravenska linija, je treba pred infuzijo in po njej linijo sprati z 0,9-odstotno raztopino natrijevega klorida.
English: • imatinib, lapatinib (used to treat cancer)
Slovenian: • imatinib, lapatinib (za zdravljenje raka)
English: Due to a hydroxymethyl group in the C5 position, tedizolid retains activity against strains of Staphylococcus aureus that express the cfr gene in the absence of chromosomal mutations.
Slovenian: Zaradi hidroksimetilne skupine v položaju C5 je pri tedizolidu ohranjena aktivnost proti sevom Staphylococcus aureus, ki izražajo gen cfr v odsotnosti kromosomskih mutacij.
English: Animal studies with tedizolid phosphate do not indicate harmful effects with respect to fertility (see section 5.3).
Slovenian: Študije na živalih s tedizolid fosfatom niso pokazale škodljivih učinkov na plodnost (glejte poglavje 5.3).
English: Sivextro vials are intended for single use only.
Slovenian: Viale z zdravilom Sivextro so samo za enkratno uporabo.
English: Antibacterial activity in combination with other antibacterial and antifungal agents
Slovenian: Protibakterijsko delovanje v kombinaciji z drugimi antibiotiki in antimikotiki
English: Frequencies are defined as: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000).
Slovenian: Pogostnosti neželenih učinkov so opredeljene kot: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000) in zelo redki (< 1/10.000).
English: Frequencies are defined as: very common (≥1/10); common (≥ 1/100 to < 1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare
Slovenian: Pogostnosti neželenih učinkov so opredeljene kot: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000) in zelo redki
English: Tedizolid phosphate should be administered with caution in patients known to be hypersensitive to other oxazolidinones since cross-hypersensitivity may occur.
Slovenian: Tedizolid fosfat je treba uporabljati previdno pri bolnikih z znano preobčutljivostjo na druge oksazolidinone, saj lahko pride do navzkrižne preobčutljivosti.
English: Do not use this medicine after the expiry date which is stated on the vial label after “EXP”.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki viale poleg oznake "EXP".
English: The recommended dose is one 200 mg tablet once a day for 6 days.
Slovenian: Priporočeni odmerek je ena 200 mg tableta enkrat dnevno 6 dni.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with Sivextro in one or more subsets of the paediatric population in the treatment of acute bacterial skin and skin structure infections (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z zdravilom Sivextro za eno ali več podskupin pediatrične populacije, zdravljenih zaradi akutnih bakterijskih okužb kože in mehkih tkiv (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Less than 3% of tedizolid phosphate administered dose is excreted as active tedizolid.
Slovenian: Manj kot 3 % uporabljenega odmerka tedizolid fosfata se izloči v obliki aktivnega tedizolida.
English: Antibacterial activity against other relevant pathogens
Slovenian: Protibakterijska aktivnost proti drugim pomembnim patogenom
English: Beta haemolytic streptococci of Groups A,B,C,G Viridans group streptococci (Streptococcus anginosus group only)
Slovenian: Betahemolitični streptokoki skupin A, B, C, G Streptokoki skupine Viridans (samo skupina Streptococcus anginosus)
English: Prescribing tedizolid phosphate in the absence of a proven or strongly suspected bacterial infection increases the risk of the development of drug-resistant bacteria.
Slovenian: Predpisovanje tedizolid fosfata brez dokazane bakterijske okužbe ali utemeljenega suma nanjo poveča tveganje za razvoj bakterij, odpornih na zdravila.
English: When incubated with pooled human liver microsomes, tedizolid was stable suggesting that tedizolid is not a substrate for hepatic CYP450 enzymes.
Slovenian: Pri inkubaciji z združenimi človeškimi jetrnimi mikrosomi je bil tedizolid stabilen, kar nakazuje, da tedizolid ni substrat za jetrne encime citokroma CYP450.
English: Sivextro must be administered by intravenous infusion over a 60-minute period.
Slovenian: Zdravilo Sivextro je treba aplicirati v intravenski infuziji v 60 minutah.
English: Controlled clinical studies did not include patients with neutropenia (neutrophil counts <1,000 cells/mm
Slovenian: V nadzorovane klinične študije niso bili vključeni bolniki z nevtropenijo (število nevtrofilcev < 1.000 celic/mm
English: Aseptic technique must be followed when preparing the infusion solution.
Slovenian: Pri pripravi raztopine za infundiranje je treba uporabiti aseptično tehniko.
English: Organisms resistant to oxazolidinones via mutations in chromosomal genes encoding 23S rRNA or ribosomal proteins (L3 and L4) are generally cross-resistant to tedizolid.
Slovenian: Organizmi, ki so odporni na oksazolidinon zaradi mutacij v kromosomskih genih, ki kodirajo 23S rRNA ali ribosomske beljakovine (L3 in L4), so običajno navzkrižno odporni na tedizolid.
English: Tedizolid is a reversible, non-selective inhibitor of monoamine oxidase (MAO) in vitro (see section 4.5).
Slovenian: Tedizolid je reverzibilen, neselektiven zaviralec monoaminooksidaze (MAO) in vitro (glejte poglavje 4.5).
English: Long-term carcinogenicity studies have not been conducted with tedizolid phosphate.
Slovenian: Dolgotrajne študije kancerogenosti s tedizolid fosfatom niso bile opravljene.
English: It will be given to you through a drip directly into a vein (intravenously) over approximately 1 hour.
Slovenian: Zdravilo boste prejeli v obliki infuzije v veno (intravensko), ki bo trajala približno 1 uro.
English: Recommended dose and duration The recommended dosage is 200 mg once daily for 6 days.
Slovenian: Priporočeni odmerek in trajanje zdravljenja Priporočeni odmerek je 200 mg enkrat dnevno 6 dni.
English: It is not known if Sivextro passes into breast milk in humans.
Slovenian: Ni znano, ali zdravilo Sivextro prehaja v materino mleko.
English: mannitol, sodium hydroxide, hydrochloric acid
Slovenian: manitol, natrijev hidroksid, klorovodikova kislina
English: For instructions on reconstitution and dilution of the medicinal product before administration, see section 6.6
Slovenian: Za navodila glede rekonstitucije in redčenja zdravila pred dajanjem glejte poglavje 6.6.
English: These findings suggest a higher frequency of infusion related reactions (phlebitis) than was observed in previous clinical studies with tedizolid phosphate.
Slovenian: Te ugotovitve kažejo na večjo pogostnost pojava reakcije na mestu infundiranja (flebitis), kot je bila opažena v prejšnjih kliničnih študijah s tedizolid fosfatom.
English: • Anxiety, irritability, shaking or trembling
Slovenian: • tesnoba, razdražljivost, tresenje ali drgetanje
English: In vitro studies in human liver microsomes indicate that tedizolid phosphate and tedizolid do not significantly inhibit metabolism mediated by any of the following CYP isoenzymes (CYP1A2, CYP2C19, CYP2A6, CYP2C8, CYP2C9, CYP2D6, and CYP3A4).
Slovenian: Študije in vitro na človeških jetrnih mikrosomih kažejo, da tedizolid fosfat in tedizolid bistveno ne zavirata presnove preko katerega koli od naslednjih izoencimov CYP (CYP1A2, CYP2C19, CYP2A6, CYP2C8, CYP2C9, CYP2D6 in CYP3A4).
English: • topotecan (used to treat cancer)
Slovenian: • topotekan (za zdravljenje raka)
English: In cases where tedizolid phosphate was discontinued, the affected haematological parameters have returned back to pre-treatment levels.
Slovenian: V primerih, ko so zdravljenje s tedizolid fosfatom opustili, so se spremenjeni hematološki parametri povrnili na enake vrednosti, kot so bile pred zdravljenjem.
English: Sivextro is administered intravenously over approximately 1 hour.
Slovenian: Zdravilo Sivextro se aplicira intravensko približno eno uro.
English: The safety profile in this study was similar to the Phase 3 clinical trials; however, infusion site reactions (phlebitis) were reported more frequently (2.7%) in tedizolid phosphate treated subjects than in the linezolid control group (0%), particularly among Asian patients.
Slovenian: Varnostni profil v študiji je bil podoben kot v kliničnih preskušanjih 3. faze, vendar je bila reakcija na mestu infundiranja (flebitis) poročana pogosteje pri bolnikih, zdravljenih s tedizolid fosfatom (2,7 %), kot pri bolnikih, zdravljenih z linezolidom (0 %), še posebej pri bolnikih azijskega porekla.
English: The film coat of the tablet contains polyvinyl alcohol, titanium dioxide (E171), macrogol, talc and yellow iron oxide (E172).
Slovenian: Filmska obloga tablete vsebuje polivinilalkohol, titanov dioksid (E171), makrogol, smukec in rumeni železov oksid (E172).
English: Table 1 Frequency of adverse reactions by System Organ Class in comparative clinical studies
Slovenian: Preglednica 1 Pogostnost neželenih učinkov po organskih sistemih v primerjalnih kliničnih študijah
English: This medicinal product contains less than 1 mmol sodium (23 mg) per dose, i.e., essentially “sodiumfree.”
Slovenian: Zdravilo Sivextro vsebuje natrij To zdravilo vsebuje manj kot 1 mmol natrija (23 mg) na odmerek, kar v bistvu pomeni 'brez natrija'.
English: Potential serotonergic interactions
Slovenian: Možne serotoninergične interakcije
English: • Decrease or loss of skin sensitivity, tingling/prickling skin sensation
Slovenian: • zmanjšanje ali izguba občutljivosti kože, mravljinčenje/zbadajoč občutek na koži
English: The effects of tedizolid phosphate on fertility in humans have not been studied.
Slovenian: Učinkov tedizolid fosfata na plodnost pri ljudeh niso raziskovali.
English: Laboratoires Merck Sharp & Dohme-Chibret Route de Marsat, Riom 63963, Clermont-Ferrand Cedex 9 France
Slovenian: Laboratoires Merck Sharp & Dohme-Chibret Route de Marsat, Riom 63963, Clermont-Ferrand Cedex 9 Francija
English: The safety and efficacy of tedizolid phosphate when administered for periods longer than 6 days have not been established (see section 4.4).
Slovenian: Varnost in učinkovitost tedizolid fosfata pri uporabi, daljši od 6 dni, nista bili dokazani (glejte poglavje 4.4).
English: Patients who commence treatment on the parenteral formulation may be switched to the oral presentation when clinically indicated.
Slovenian: Bolniki, ki so začeli zdravljenje s parenteralno obliko zdravila, lahko preidejo na peroralno obliko, kadar je to klinično indicirano.
English: • Swelling in ankles and/or feet
Slovenian: • zatečeni gležnji in/ali stopala
English: The AUC/MIC ratio was the pharmacodynamic parameter shown to best correlate with efficacy in mouse thigh and lung S. aureus infection models.
Slovenian: Razmerje AUC/MIK je farmakodinamični parameter, ki najbolje korelira z učinkovitostjo pri mišjih modelih okužbe stegna in pljuč z bakterijo S. aureus.
English: Oval (13.8 mm long by 7.4 mm wide) yellow film-coated tablet debossed with “TZD” on the obverse side and “200” on the reverse side.
Slovenian: Ovalne (13,8 mm dolge in 7,4 mm široke) rumene filmsko obložene tablete z vtisnjenima oznakama "TZD" na eni in "200" na drugi strani.