FrancophonIA/ELRC3.0 huggingface dataset:
English: * In a combined analysis from several clinical studies, atazanavir/ritonavir 300/100 mg co-administered with tenofovir disoproxil fumarate 300 mg (n=39) was compared to atazanavir/ritonavir 300/100 mg (n=33).
Danish: * I en kombineret analyse af flere kliniske studier, hvor samtidig administration af atazanavir/ritonavir 300/100 mg og tenofovirdisoproxilfumarat 300 mg (n=39) blev sammenlignet med atazanavir/ritonavir 300/100 mg (n=33).
English: If a higher dose of an H2-receptor antagonist is required (e.g., famotidine 40 mg twice daily or equivalent) an increase of the REYATAZ/ritonavir dose from 300/100 mg to 400/100 mg can be considered.
Danish: Hvis en højere dosis H2-receptorantagonist er nødvendig (f.eks. famotidin 40 mg 2 gange dagligt eller tilsvarende), kan dosisøgning af REYATAZ/ritonavir fra 300/100 mg til 400/100 mg overvejes.
English: REYATAZ should not be used in combination with medicinal products that are substrates of CYP3A4 and have a narrow therapeutic index.
Danish: REYATAZ bør ikke anvendes i kombination med lægemidler, der er CYP3A4-substrater, og som har et snævert terapeutisk indeks.
English: CD4 count <50 cells/mm3
Danish: CD4-celletal <50 celler/mm3
English: Voriconazole AUC ↑561% (↑451% Voriconazole Cmax ↑438% (↑355% Voriconazole Cmin ↑765% (↑571%
Danish: Voriconazol AUC ↑561% (↑451% Voriconazol Cmax ↑438% (↑355% Voriconazol Cmin ↑765% (↑571%
English: The pharmacokinetic data from HIV-infected pregnant women receiving REYATAZ capsules with ritonavir are presented in Table 8.
Danish: De farmakokinetiske data fra hiv-smittede gravide kvinder, der fik REYATAZ kapsler med ritonavir, er beskrevet i Tabel 8.
English: Serious skin rash, including Stevens-Johnson syndrome, has been reported in patients taking REYATAZ.
Danish: Der er rapporteret alvorligt hududslæt, herunder Stevens-Johnsons syndrom (se afsnit 4), hos patienter, der tager REYATAZ.
English: How to take REYATAZ
Danish: Sådan skal du tage REYATAZ
English: Co-administration of REYATAZ with voxilaprevir-containing regimens is not recommended.
Danish: Samtidig administration af REYATAZ med regimer der indeholder voxilaprevir frarådes.
English: Additional infant formula, beverage or food may be given after consumption of the entire mixture.
Danish: Barnet kan mades med mere modermælkserstatning, væske eller føde efter indgivelse af hele blandingen.
English: When given with REYATAZ/ritonavir, the recommended dose of rifabutin is 150 mg 3 times per week on set days (for example MondayWednesday-Friday).
Danish: Når rifabutin gives sammen med REYATAZ/ritonavir, er den anbefalede rifabutindosis 150 mg 3 gange ugentligt på fastsatte dage (for eksempel mandag-onsdag-fredag).
English: Weight and levels of blood lipids and glucose may increase during antiretroviral therapy (see section 4.4).
Danish: Kropsvægt og niveauerne af lipid og glucose i blodet kan stige under antiretroviral behandling (se pkt.
English: uncommon: torsades de pointesa rare: QTc prolongationa, oedema, palpitation
Danish: ikke almindelig: torsades de pointesa sjælden: QTc-forlængelsea, ødem, palpitation
English: Driving and using machines If you feel dizzy or lightheaded, do not drive or use machines, and contact your doctor immediately.
Danish: Hvis du føler dig svimmel eller uklar, må du ikke køre bil eller betjene maskiner, og du skal straks kontakte lægen.
English: *Lack of pharmacokinetics interaction bounds 70-143%
Danish: *Interval på 70-143%, hvor der ikke er farmakokinetisk interaktion
English: REYATAZ/ritonavir should not be used in combination with medicinal products that are substrates of CYP3A4 and have a narrow therapeutic index.
Danish: REYATAZ/ritonavir bør ikke anvendes i kombination med lægemidler, der er CYP3A4-substrater, og som har et snævert terapeutisk indeks.
English: Concentrations of these antiarrhythmics may be increased when co-administered with REYATAZ.
Danish: Koncentrationer af disse antiarytmika kan øges ved samtidig administration af REYATAZ.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON TEXT
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE TEKST PÅ YDRE ÆSKE
English: The child is to drink the mixture.
Danish: Barnet skal drikke blandingen.
English: If you have been told by your doctor that your child has an intolerance to some sugars, contact your doctor before giving this medicinal product to your child.
Danish: Kontakt lægen, før du giver denne medicin til dit barn, hvis lægen har fortalt dig, at din barn ikke tåler visse sukkerarter.
English: Co-administration of REYATAZ with these medicinal products is expected to substantially increase their concentrations and may result in PDE5-associated adverse reactions such as hypotension, visual changes and priapism (see section 4.5).
Danish: Samtidig administration af REYATAZ med disse lægemidler forventes at øge deres koncentration væsentligt og kan resultere i PDE5-relaterede bivirkninger såsom hypotension, synsforstyrrelser og priapisme (se pkt.
English: Prior to mixing, the sachet is tapped to settle the powder.
Danish: Inden blanding bankes der let på brevet for at samle pulveret.
English: Add an additional tablespoon in the container, mix and feed to your child again.
Danish: Tilsæt en ekstra spiseskefuld mad, rør rundt og mad barnet igen.
English: Particular caution should be used when prescribing REYATAZ in association with medicinal products which have the potential to increase the QT interval and/or in patients with preexisting risk factors (bradycardia, long congenital QT, electrolyte imbalances (see sections 4.8 and 5.3).
Danish: Man bør udvise særlig forsigtighed, når REYATAZ ordineres samtidig med lægemidler, som kan forøge QT-intervallet og/eller til patienter med allerede eksisterende risikofaktorer (bradykardi, medfødt langt QT, elektrolytforstyrrelser (se pkt.
English: Didanosine should be taken at the fasted state 2 hours after REYATAZ/ritonavir taken with food.
Danish: Didanosin skal tages fastende, 2 timer efter indtagelse af REYATAZ/ritonavir, taget til et måltid.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/03/267/001-006; 008-011
Danish: EU/1/03/267/001-006; 008-011
English: Increased monitoring for rifabutin-associated adverse reactions including neutropenia and uveitis is warranted due to an expected increase in exposure to rifabutin.
Danish: Øget overvågning for rifabutinassocierede bivirkninger inklusive neutropeni og uveitis er påkrævet pga. en forventet øget rifabutineksponering.
English: HIV RNA <50 copies/ml, %a at least 5 to < 10 kg (REYATAZ 150 and 200 mg) at least 10 to < 15 kg at least 15 to < 25 kg at least 25 to < 35 kg
Danish: hiv-RNA <50 kopier/ml, %a mindst 5 til < 10 kg (REYATAZ 150 og 200 mg) mindst 10 til < 15 kg mindst 15 til < 25 kg mindst 25 til < 35 kg hiv-RNA <400 kopier/ml, %a mindst 5 til < 10 kg (REYATAZ 150 og 200 mg) mindst 10 til < 15 kg mindst 15 til < 25 kg mindst 25 til < 35 kg
English: Carbamazepine should be used with caution in combination with REYATAZ.
Danish: Carbamazepin bør anvendes med forsigtighed sammen med REYATAZ.
English: Concomitant use of REYATAZ/ritonavir and fluticasone or other glucocorticoids that are metabolised by CYP3A4 is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression (see section 4.5).
Danish: Samtidig brug af REYATAZ og fluticason, eller andre glukokortikoider, som metaboliseres af CYP3A4, frarådes, medmindre de potentielle fordele ved behandlingen opvejer risikoen for systemiske bivirkninger forårsaget af kortikosteroider, herunder Cushings syndrom og binyrebarksuppression (se pkt.
English: When co-administered with tenofovir disoproxil fumarate, it is recommended that REYATAZ 300 mg be given with ritonavir 100 mg and tenofovir disoproxil fumarate 300 mg (all as a single dose with food).
Danish: Ved administration sammen med tenofovirdisoproxilfumarat anbefales det at give REYATAZ 300 mg med ritonavir 100 mg og tenofovirdisoproxilfumarat 300 mg (alle som en enkeltdosis sammen med mad).
English: Given that low dose ritonavir (100 mg twice daily) has been shown to have no significant effect on methadone concentrations, no interaction is expected if methadone is coadministered with REYATAZ, based on these data.
Danish: Lav ritonavirdosis (100 mg 2 gange dagligt) er vist ikke at have signifikant effekt på methadon-koncentrationen, og på baggrund af disse data forventes ingen interaktion ved samtidig administration af methadon og REYATAZ.
English: The dose of REYATAZ capsules for children is calculated by body weight and is taken once daily with food and 100 mg ritonavir as shown below:
Danish: Dosis af REYATAZ-kapsler til børn beregnes ud fra barnets vægt og skal tages en gang dagligt sammen med mad og 100 mg ritonavir som vist i tabellen nedenfor:
English: When given with REYATAZ, the recommended dose of rifabutin is 150 mg 3 times per week on set days (for example Monday-Wednesday-Friday).
Danish: Når rifabutin gives sammen med REYATAZ, er den anbefalede rifabutindosis 150 mg 3 gange ugentligt på fastsatte dage (for eksempel mandag-onsdagfredag).
English: Put the syringe tip into the mixture and pull back the plunger until the full amount of infant formula is taken up.
Danish: Stik spidsen af sprøjten ned i blandingen og træk stemplet tilbage, indtil den nødvendige mængde modermælkserstatning er trukket op i sprøjten.
English: Co-administration of quetiapine with REYATAZ is contraindicated as REYATAZ may increase quetiapine-related toxicity.
Danish: Samtidig administration af quetiapin og REYATAZ er kontraindiceret, da REYATAZ kan øge quetiapin-relateret toksicitet.
English: The dose and the number of REYATAZ oral powder sachets needed is determined based on weight (see section 4.2.
Danish: Dosis og det nødvendige antal breve med REYATAZ oralt pulver er baseret på legemsvægten (se pkt.
English: Among patients who received REYATAZ 400 mg once daily or REYATAZ 300 mg with ritonavir 100 mg once daily, the only adverse reactions of any severity reported very commonly with at least a possible relationship to regimens containing REYATAZ and one or more NRTIs were nausea (20%), diarrhoea (10%), and jaundice (13%).
Danish: Blandt patienter, der fik REYATAZ 400 mg, én gang dagligt, eller REYATAZ 300 mg med 100 mg ritonavir, én gang dagligt, var de eneste meget almindelige bivirkninger, af nogen sværhedsgrad og med mindst en mulig forbindelse til regimer indeholdende REYATAZ og én eller flere NRTIer: kvalme (20%), diarré (10%) og gulsot (13%).
English: PDE5 inhibitors used for the treatment of erectile dysfunction: particular caution should be used when prescribing PDE5-inhibitors (sildenafil, tadalafil, or vardenafil) for the treatment of erectile dysfunction in patients receiving REYATAZ.
Danish: PDE5-hæmmere ved behandling af erektil dysfunktion: Der bør udvises særlig forsigtighed ved ordinering af PDE5-hæmmere (sildenafil, tadalafil eller vardenafil) til behandling af erektil dysfunktion hos patienter, der får REYATAZ.
English: Put another 10 ml of prepared infant formula in the cup or container and rinse the remaining oral powder from the cup or container.
Danish: Hæld yderligere 10 ml tilberedt modermælkserstatning i koppen eller beholderen for at skylle det resterende REYATAZ oralt pulver ud af koppen.
English: Driving and using machines If you feel dizzy or lightheaded, do not drive or use machines and contact your doctor immediately.
Danish: Hvis du føler dig svimmel eller uklar, må du ikke køre bil eller betjene maskiner og du skal straks kontakte lægen.
English: CD4 Mean Change from Baseline, cells/mm3 All patients
Danish: CD4 Middelændring fra baseline, celler/mm3 Alle patienter
English: d Intent-to-treat analysis, with missing values considered as failures.
Danish: d Intent-to-treat-analyse hvor manglende værdier anses som svigt.
English: PDE5 inhibitors used for the treatment of erectile dysfunction: particular caution should be used when prescribing PDE5-inhibitors (sildenafil, tadalafil, or vardenafil) for the treatment of erectile dysfunction in patients receiving REYATAZ with concomitant low-dose ritonavir.
Danish: PDE5-hæmmere ved behandling af erektil dysfunktion: Der bør udvises særlig forsigtighed ved ordinering af PDE5-hæmmere (sildenafil, tadalafil eller vardenafil) til behandling af erektil dysfunktion hos patienter, der får REYATAZ samtidig med lavdosis ritonavir.
English: Also see PULMONARY ATERIAL HYPERTENSION in this table for further information regarding co-administration of REYATAZ/ritonavir with sildenafil.
Danish: Se også PULMONAL ARTERIEL HYPERTENSION i denne tabel for yderligere information om samtidig administration af REYATAZ/ritonavir og sildenafil.
English: REYATAZ with ritonavir should be used with caution in patients with mild hepatic impairment.
Danish: REYATAZ med ritonavir bør anvendes med forsigtighed til patienter med let nedsat leverfunktion.
English: HCV Protease Inhibitors
Danish: HCV-proteasehæmmere
English: * When compared to REYATAZ 300 mg/ritonavir 100 mg once daily in the evening without efavirenz.
Danish: * Sammenlignet med REYATAZ 300 mg/ritonavir 100 mg én gang dagligt om aftenen uden efavirenz.
English: If REYATAZ is co-administered with irinotecan, patients should be closely monitored for adverse events related to irinotecan.
Danish: Hvis REYATAZ administreres samtidig med irinotecan, bør patienten monitoreres tæt for irinotecan-relaterede bivirkninger.
English: Gallbladder problems uncommonly happen in people taking REYATAZ.
Danish: Galdeblæreproblemer kan forekommme mindre hyppigt hos personer, der tager REYATAZ.
English: Reversible elevations in indirect (unconjugated) bilirubin related to inhibition of UDP-glucuronosyl transferase (UGT) have occurred in patients receiving REYATAZ (see section 4.8).
Danish: Der er set reversible forhøjelser i indirekte (ukonjugeret) bilirubin relateret til hæmning af UDPglucuronosyltransferase (UGT) hos patienter i behandling med REYATAZ (se pkt.
English: REYATAZ capsules are available for paediatric patients at least 6 years of age who weigh at least 15 kg and who are able to swallow capsules (see Summary of Product Characteristics for REYATAZ
Danish: REYATAZ kapsler fås til pædiatriske patienter, som er mindst 6 år og vejer mindst 15 kg og er i stand til at sluge kapsler (se produktresumeet for REYATAZ kapsler).
English: PHARMACEUTICAL FORM AND CONTENTS Oral Powder
Danish: LÆGEMIDDELFORM OG ANTAL (PAKNINGSSTØRRELSE) Oralt pulver
English: No dosage adjustments are needed for REYATAZ/ritonavir and fluconazole.
Danish: Dosisjustering er ikke nødvendig for REYATAZ/ritonavir og fluconazol.
English: Didanosine should be taken at the fasted state 2 hours after REYATAZ taken with food.
Danish: Didanosin skal tages fastende, 2 timer efter indtagelse af REYATAZ, taget til et måltid.
English: SEDATIVES Benzodiazepines
Danish: Benzodiazepiner
English: By as-treated analysis, excluding missing values, the proportions of patients with HIV RNA < 400 copies/ml (< 50 copies/ml) in the REYATAZ + ritonavir arm and the lopinavir + ritonavir arm were 55% (40%) and 56% (46%), respectively.
Danish: Andelen af patienter med hiv-RNA <400 kopier/ml (< 50 kopier/ml) i REYATAZ + ritonavir-armen og lopinavir + ritonavir-armen var henholdsvis 55% (40%) og 56% (46%).
English: Co-administration of REYATAZ and medicinal products that induce CYP3A4 is not recommended (see sections 4.3 and 4.5).
Danish: Samtidig administration af REYATAZ og lægemidler, der inducerer CYP3A4 frarådes (se pkt.
English: Six of 20 (30%) women on REYATAZ/ritonavir 300/100 mg and 13 of 21 (62%) women on REYATAZ/ritonavir 400/100 mg experienced grades 3 to 4 hyperbilirubinaemia.
Danish: Seks ud af 20 (30%) kvinder, der fik REYATAZ/ritonavir 300/100 mg og 13 ud af 21 (62%) kvinder, der fik REYATAZ/ritonavir 400/100 mg oplevede grad 3 til 4 hyperbilirubinæmi.
English: Paediatric trials with REYATAZ oral powder
Danish: Pædiatriske studier med REYATAZ oralt pulver
English: REYATAZ oral powder must be taken with ritonavir and has to be taken with food.
Danish: REYATAZ oralt pulver skal tages sammen med ritonavir og i forbindelse med et måltid.
English: Choose the appropriate option listed below for giving REYATAZ oral powder to your child.
Danish: Vælg en af nedenstående måder, hvorpå du kan give dit barn REYATAZ oralt pulver.
English: REYATAZ Dose once daily (mg)
Danish: REYATAZ en daglig dosis (mg)
English: The recommended dose of REYATAZ capsules is 300 mg once daily taken with ritonavir 100 mg once daily and with food.
Danish: Anbefalet dosis REYATAZ-kapsler er 300 mg én gang dagligt sammen med 100 mg ritonavir én gang dagligt og i forbindelse med et måltid.
English: The most frequently reported laboratory abnormality in paediatric patients receiving REYATAZ was elevation of total bilirubin (≥ 2.6 times ULN, Grade 3-4) which occurred in 45% of patients.
Danish: Den hyppigst rapporterede laboratoriemæssige anormalitet hos pædiatriske patienter i behandling med REYATAZ var forhøjet total-bilirubin (≥ 2,6 gange ULN, grad 3-4), som forekom hos 45% af patienterne.
English: Quinidine has a narrow therapeutic window and is contraindicated due to potential inhibition of CYP3A by REYATAZ/ritonavir.
Danish: Quinidin har et snævert terapeutisk indeks og er kontraindiceret pga. risiko for CYP3Ahæmning med REYATAZ/ritonavir.
English: The full amount of the mixture is drawn up into an oral syringe and administered into either right or left inner cheek of the infant.
Danish: Hele blandingen trækkes op i en mundsprøjte og indgives enten i barnets højre eller venstre kindhule.
English: Have the child drink the mixture.
Danish: Få barnet til at drikke blandingen.
English: Concentrations of these antiarrhythmics may be increased when co-administered with REYATAZ/ritonavir.
Danish: Koncentrationer af disse antiarytmika kan øges ved samtidig administration af REYATAZ/ritonavir.
English: No dosage adjustments are needed for fluconazole and REYATAZ.
Danish: Dosisjustering er ikke nødvendig for fluconazol og REYATAZ.
English: REYATAZ with ritonavir has not been studied in patients with hepatic impairment.
Danish: REYATAZ med ritonavir har ikke været undersøgt hos patienter med nedsat leverfunktion.
English: Off white to pale yellow powder.
Danish: Råhvidt til lysegult pulver.
English: NAME OF THE MARKETING AUTHORISATION HOLDER BRISTOL-MYERS SQUIBB PHARMA EEIG
Danish: NAVN PÅ INDEHAVEREN AF MARKEDSFØRINGSTILLADELSEN BRISTOL-MYERS SQUIBB PHARMA EEIG 3.
English: Do not use this medicine after the expiry date which is stated on the carton or sachet.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på æsken eller brevet efter Exp. Udløbsdatoen er den sidste dag i den nævnte måned.
English: The mechanism of interaction is decreased solubility of atazanavir as intra-gastric pH increases with H2blockers.
Danish: Interaktionsmekanismen er nedsat opløselighed af atazanavir pga. intragastrisk pH-stigning med H2blokkere.
English: (n=90
Danish: (n=90e)
English: Rare (may affect up to 1 in 1,000 people): gait disturbance (abnormal manner of walking) oedema (swelling) hepatosplenomegaly (enlargement of the liver and spleen) myopathy (aching muscles, muscle tenderness of weakness, not caused by exercise) kidney pain
Danish: Sjældne (kan forekomme hos op til 1 ud af 1.000 personer): gangforstyrrelser væskeophobninger forstørrelse af lever og milt muskelsmerter og muskelømhed på grund af svaghed, der ikke er forårsaget af motion nyresmerter
English: * When compared to REYATAZ 300 mg and ritonavir 100 mg without nevirapine.
Danish: * Sammenlignet med REYATAZ 300 mg/ritonavir 100 mg uden nevirapin.
English: Atazanavir and fluconazole concentrations were not significantly modified when REYATAZ/ritonavir was co-administered with fluconazole.
Danish: Atazanavir- og fluconazolkoncentrationerne ændredes ikke signifikant ved samtidig administration af REYATAZ/ritonavir og fluconazol.
English: * In a combined analysis, atazanavir 300 mg and ritonavir 100 mg (n=33) was compared to atazanavir 400 mg without ritonavir (n=28).
Danish: * Atazanavir 300 mg og ritonavir 100 mg (n=33) er i en kombineret analyse sammenlignet med atazanavir 400 mg uden ritonavir (n=28).
English: A safe and effective dose in combination with REYATAZ has not been established for sildenafil when used to treat pulmonary arterial hypertension.
Danish: Der er ikke fastlagt en sikker og effektiv dosis for sildenafil i kombination med REYATAZ til behandling af pulmonal arteriel hypertension.
English: Do not throw away any medicines via wastewater or household waste.
Danish: Af hensyn til miljøet må du ikke smide medicinrester i afløbet, eller toilettet eller skraldespanden.
English: HIV RNA <50 copies/ml by select baseline PI substitutions,c % (responder/evaluabled) NA
Danish: hiv-RNA <50 kopier/ml ved selekteret baseline PI-substitution,c % (respondent/evaluerbard)
English: Desacetyl-diltiazem AUC ↑165% Desacetyl-diltiazem Cmax ↑172% Desacetyl-diltiazem Cmin ↑121%
Danish: Desacetyl-diltiazem Cmin ↑121%
English: Excipient with known effect: 82.18 mg of lactose per capsule.
Danish: Hjælpestof, som behandleren skal være opmærksom på: 82,18 mg lactose per kapsel.
English: 15 to less than 35 at least 35
Danish: 15 til under 35 mindst 35
English: After mixing the oral powder with food or drinks, it may be stored at room temperature (not above 30oC) for up to 1 hour.
Danish: Efter opblanding med mad eller drikke, kan blandingen opbevares i op til 1 time ved stuetemperatur (ikke over 30°C).
English: If REYATAZ/ritonavir is coadministered with irinotecan, patients should be closely monitored for adverse events related to irinotecan.
Danish: Hvis REYATAZ/ritonavir administreres samtidig med irinotecan, bør patienten monitoreres tæt for irinotecanrelaterede bivirkninger.
English: 50 to <100 cells/mm3
Danish: 50 to <100 celler/mm3
English: Patients should be warned about these possible side effects when using PDE5 inhibitors for erectile dysfunction with REYATAZ (see section 4.4).
Danish: Patienterne bør advares om risikoen for disse bivirkninger ved brug af PDE5-hæmmere mod erektil dysfunktion samtidig med REYATAZ (se pkt.
English: Due to CYP3A4 inhibition by REYATAZ, concentrations of quetiapine are expected to increase.
Danish: Da REYATAZ hæmmer CYP3A4, forventes koncentrationen af quetiapin at stige.
English: Co-administration with REYATAZ/ritonavir may cause a large increase in the concentration of these benzodiazepines.
Danish: Administration sammen med REYATAZ/ritonavir kan medføre en stor stigning i koncentrationen af disse benzodiazepiner.
English: For details on preparation and administration of the REYATAZ oral powder and Instructions for Use, see section 6.6.
Danish: For instruktioner om klargøring og administration af REYATAZ oralt pulver og brugsvejledning, se pkt.
English: Skin rash, itching that may occasionally be severe has been reported.
Danish: Der er rapporteret om hududslæt og kløe, som i nogle tilfælde kan være alvorligt.
English: In HIV-infected adult patients (n=33, combined studies) the mean half-life within a dosing interval for atazanavir was 12 hours at steady state following a dose of 300 mg daily with ritonavir 100 mg once daily with a light meal.
Danish: Gennemsnitlig halveringstid var, inden for atazanavirs dosisinterval, hos hiv-inficerede voksne patienter (n=33, kombinerede studier) 12 timer ved steady state efter en dosis på 300 mg dagligt med 100 mg ritonavir én gang dagligt med et let måltid.
English: Excipient with known effect: 164.36 mg of lactose per capsule.
Danish: Hjælpestof, som behandleren skal være opmærksom på: 164,36 mg lactose per kapsel.
English: CORTICOSTEROIDS Fluticasone propionate intranasal 50 µg 4 times daily for 7 days (ritonavir 100 mg capsules twice daily)
Danish: Fluticasonpropionat intranasalt 50 µg 4 gange dagligt i 7 dage (ritonavir 100 mg kapsler 2 gange dagligt)
English: Co-administration of lurasidone with REYATAZ is contrandicated as this may increase lurasidone-related toxicity (see section 4.3).
Danish: Samtidig administration af lurasidon og REYATAZ er kontraindiceret, da dette kan øge lurasidon-relateret toksicitet (se pkt.