FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients should be instructed that any solution left in the bottle 45 days after opening should be disposed of in accordance with local requirements or returned to the pharmacy.
Croatian: Pacijente je potrebno upozoriti da je neiskorištenu otopinu koja preostane u boci 45 dana nakon otvaranja potrebno zbrinuti sukladno nacionalnim propisima ili vratiti u ljekarnu.
English: Such exacerbations have been seen following discontinuation of emtricitabine treatment in HBV infected patients without concomitant HIV infection and have been detected primarily by serum alanine aminotransferase (ALT) elevations in addition to re-emergence of HBV DNA.
Croatian: Pogoršanja su zabilježena nakon prekida liječenja emtricitabinom u pacijenata inficiranih HBV-om bez istovremene infekcije HIV-om te su primarno otkrivena na temelju povišenja alanin-aminotransferaza (ALT-a) u serumu uz ponovnu pojavu HBV DNK.
English: The bottle contains 170 mL of solution.
Croatian: Boca sadrži 170 mL otopine.
English: Relevant examples include cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jirovecii pneumonia.
Croatian: Relevantni primjeri obuhvaćaju citomegalovirusni retinitis, generalizirane i/ili žarišne mikobakterijske infekcije te upala pluća uzrokovana s Pneumocystis jirovecii.
English: In case of concomitant antiviral therapy for hepatitis B or C, please also refer to the relevant Summary of Product Characteristics for these medicinal products.
Croatian: U slučaju istovremenog antivirusnog liječenja hepatitisa B ili C pročitajte i sažetak opisa svojstava lijeka za te lijekove.
English: How to store Emtriva
Croatian: Kako uzimati Emtrivu
English: In general, emtricitabine pharmacokinetics in HBV infected subjects were similar to those in healthy subjects and in HIV infected subjects.
Croatian: Općenito je farmakokinetika emtricitabina u osoba inficiranih virusom HBV-a bila slična farmakokinetici u zdravih ispitanika i u HIV-om zaraženih ispitanika.
English: Emtricitabine did not inhibit the enzyme responsible for glucuronidation.
Croatian: Emtricitabin nije inhibirao enzim odgovoran za glukuronidaciju.
English: If there is any solution left in the bottle after 45 days, this should be disposed of in accordance with local requirements or returned to the pharmacy.
Croatian: Neiskorištenu otopinu koja preostane u boci nakon 45 dana valja zbrinuti sukladno s lokalnim propisima ili vratiti u ljekarnu.
English: In infants and children older than 4 months, the majority of patients achieved or maintained complete suppression of plasma HIV-1 RNA through 48 weeks (89% achieved ≤ 400 copies/mL and 77% achieved ≤ 50 copies/mL).
Croatian: U dojenčadi i djece starije od 4 mjeseca većina je pacijenata postigla ili održala potpunu supresiju HIV-1 RNK u plazmi tijekom 48 tjedana (89% postiglo je ≤ 400 kopija/mL, a 77% postiglo je
English: 3 This adverse reaction, which was identified through post-marketing surveillance, was not observed in randomised controlled clinical trials in adults or paediatric HIV clinical trials of emtricitabine.
Croatian: 3 Ova nuspojava prepoznata je tijekom praćenja lijeka nakon stavljanja u promet, ali nije opažena u randomiziranim kontroliranim kliničkim ispitivanjima emtricitabina u odraslih ili u kliničkim ispitivanjima emtricitabina u pedijatrijskih pacijenata inficiranih HIV-om.
English: • If you have problems with your kidneys, your doctor may advise you to take Emtriva less frequently.
Croatian: • Ako imate problema s bubrezima, možda će Vas liječnik uputiti da rjeđe uzimate Emtrivu.
English: There are no clinically significant interactions when emtricitabine is co-administered with indinavir, zidovudine, stavudine, famciclovir or tenofovir disoproxil fumarate.
Croatian: Nema klinički značajnih interakcija prilikom istovremene primjene emtricitabina s indinavirom, zidovudinom, stavudinom, famciklovirom ili tenofovirdizoproksil fumaratom.
English: Emtriva should not be taken with any other medicinal products containing emtricitabine or medicinal products containing lamivudine.
Croatian: Emtriva se ne smije uzimati istovremeno s drugim lijekovima koji sadrže emtricitabin ni s lijekovima koji sadrže lamivudin.
English: If there is evidence of exacerbations of liver disease in such patients, interruption or discontinuation of treatment must be considered.
Croatian: Ako u tih pacijenata nastupe znakovi egzacerbacije bolesti jetre, mora se uzeti u obzir privremen ili trajan prekid liječenja.
English: Immune Reactivation Syndrome: In HIV infected patients with severe immune deficiency at the time of initiation of CART, an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Croatian: Sindrom imunološke reaktivacije: U pacijenata inficiranih HIV-om s teškom imunodeficijencijom u vrijeme početka CART-a može nastati upalna reakcija na asimptomatske ili rezidualne oportunističke infekcije.
English: The following side effects are very common (these can affect at least 10 in every 100 patients):
Croatian: Sljedeće nuspojave su vrlo česte (mogu se javiti u najmanje 10 na svakih 100 pacijenata):
English: For infants from 4 months, children, and patients who are unable to swallow hard capsules and patients with kidney problems, Emtriva is available as a liquid (an oral solution).
Croatian: Za dojenčad od 4 mjeseca starosti, djecu i pacijente koji ne mogu progutati tvrde kapsule te pacijente s bubrežnim tegobama Emtriva je dostupna kao tekućina (oralna otopina).
English: • Infants, children and adolescents weighing 40 kg or less: the dose of Emtriva 10 mg/mL oral solution is calculated according to your body weight.
Croatian: • Dojenčad, djeca i adolescenti do tjelesne težine od 40 kg: doza Emtriva 10 mg/mL oralne otopine određuje se prema tjelesnoj težini.
English: The clear solution is orange to dark orange in colour.
Croatian: Bistra otopina je narančaste do tamnonarančaste boje.
English: These findings should be considered for any child exposed in utero to nucleos(t)ide analogues, who present with severe clinical findings of unknown etiology, particularly neurologic findings.
Croatian: Te nalaze treba uzeti u obzir u svakog djeteta koje je in utero bilo izloženo nukleozidnim i nukleotidnim analozima, a ima tešku kliničku sliku nepoznate etiologije, osobito neurološke nalaze.
English: If you have difficulty in swallowing the capsules, tell your doctor.
Croatian: Ako ne možete progutati kapsule, obavijestite o tome svog liječnika.
English: Antiviral activity in vitro: The 50% inhibitory concentration (IC50) value for emtricitabine against laboratory and clinical isolates of HIV-1 was in the range of 0.0013 to 0.5 µmol/l.
Croatian: Antivirusno djelovanje in vitro: Vrijednost inhibitorne koncentracije pri 50% (IK50) emtricitabina na laboratorijske i kliničke izolate virusa HIV-1 u rasponu je od 0,0013 do 0,5 µmol/L.
English: Ethnicity No clinically important pharmacokinetic difference due to ethnicity has been identified.
Croatian: Etnička pripadnost Nisu ustanovljene klinički važne razlike u farmakokinetici vezane uz etničku pripadnost.
English: There is no experience of the use of Emtriva in patients who are failing their current regimen or who have failed multiple regimens (see section 5.1).
Croatian: Nema iskustva primjene Emtrive u pacijenata u kojih trenutno liječenje nije uspješno ili u kojih višestruki režimi liječenja nisu bili uspješni (vidjeti dio 5.1).
English: Plasma emtricitabine exposure (AUC) in infants up to 3 months of age who received 3 mg/kg emtricitabine once daily was similar to that observed using 6 mg/kg daily doses in HIV infected adults and children aged 4 months and over.
Croatian: Izloženost emtricitabinu u plazmi (AUC) u dojenčadi do 3 mjeseca starosti koja su primala 3 mg/kg emtricitabina jedanput na dan bila je slična izloženosti zabilježenoj pri dozama od 6 mg/kg jedanput na dan u HIV-om inficiranih odraslih i djece od 4 mjeseca i starije.
English: 2 Anaemia was common and skin discolouration (increased pigmentation) was very common when emtricitabine was administered to paediatric patients (see section 4.8, Paediatric population).
Croatian: 2 Anemija je bila česta, a promjena boje kože (povećana pigmentacija) vrlo česta kad se emtricitabin primjenjivao u pedijatrijskih pacijenata (vidjeti dio 4.8, Pedijatrijska populacija).
English: In vitro, emtricitabine did not inhibit metabolism mediated by any of the following human CYP450 isoforms: 1A2, 2A6, 2B6, 2C9, 2C19, 2D6 and 3A4.
Croatian: In vitro, emtricitabin nije inhibirao metabolizam posredovan nekim od sljedećih izoenzima CYP450 u ljudi: 1A2, 2A6, 2B6, 2C9, 2C19, 2D6 i 3A4.
English: Hepatic insufficiency: No data are available on which to make a dose recommendation for patients with hepatic insufficiency.
Croatian: Insuficijencija jetre: Ne postoje podaci na temelju kojih bi se mogla preporučiti doza za pacijente s insuficijencijom jetre.
English: Contains E110, E216, E218, sodium and propylene glycol, see leaflet for further information.
Croatian: POPIS POMOĆNIH TVARI Sadrži E110, E216, E218, natrij i propilenglikol, dodatne informacije potražite u uputi o lijeku.
English: Emtricitabine is rapidly and extensively absorbed following oral administration with peak plasma concentrations occurring at 1 to 2 hours post-dose.
Croatian: Emtricitabin se vrlo brzo i opsežno apsorbira nakon peroralne primjene, a najveće su koncentracije u plazmi 1 do 2 sata nakon primjene.
English: The use of emtricitabine in patients with chronic HBV induces the same mutation pattern in the YMDD motif observed with lamivudine therapy.
Croatian: Primjena emtricitabina u pacijenata s kroničnom infekcijom HBV-om potiče stvaranje jednakih obrazaca mutacije YMDD motiva primijećenih prilikom liječenja lamivudinom.
English: • low white blood cell count (a reduced white blood cell count can make you more prone to infection)
Croatian: Pretrage mogu također pokazati: • nizak broj bijelih krvnih stanica (zbog smanjenog broja bijelih krvnih stanica možete postati skloniji infekcijama)
English: Psychiatric disorders: Common:
Croatian: Psihijatrijski poremećaji:
English: Each dose (24 mL) contains 36 mg methyl parahydroxybenzoate (E218), 3.6 mg propyl parahydroxybenzoate (E216), 1.2 mg sunset yellow (E110), 480 mg propylene glycol and has a sodium content of 36 mg.
Croatian: Svaka doza (24 mL) sadrži 36 mg metilparahidroksibenzoata (E218), 3,6 mg propilparahidroksibenzoata (E216), 1,2 mg boje sunset yellow (E110), 480 mg propilenglikola te
English: How much 10 mg/mL solution to take (mL)
Croatian: Koliko otopine od 10 mg/mL uzeti (mL)
English: Emtriva oral solution is a clear, orange to dark orange solution that comes in bottles containing 170 mL with a measuring cup.
Croatian: Oralna otopina Emtriva bistra je otopina narančaste do tamnonarančaste boje i isporučuje se u bocama koje sadrže 170 mL te uz odmjernu čašicu.
English: No data are available on which to make a dose recommendation in paediatric patients with renal insufficiency.
Croatian: Ne postoje podaci na temelju kojih bi se mogla preporučiti doza za pedijatrijske pacijente s insuficijencijom bubrega.
English: Mitochondrial dysfunction following exposure in utero Nucleos(t)ide analogues may impact mitochondrial function to a variable degree, which is most pronounced with stavudine, didanosine and zidovudine.
Croatian: Poremećaj funkcije mitohondrija nakon izloženosti in utero Analozi nukleozida i nukleotida mogu, u različitom stupnju, utjecati na funkciju mitohondrija, a taj je utjecaj najizraženiji uz stavudin, didanozin i zidovudin.
English: Gilead Sciences Tél: + 33 (0) 1 46 09 41 00
Croatian: Tél: + 33 (0) 1 46 09 41 00
English: hypertriglyceridaemia, hyperglycaemia
Croatian: hipertrigliceridemija, hiperglikemija
English: The safety and efficacy of the reduced doses provided in section 4.2 are based on single dose pharmacokinetic data and modelling and have not been clinically evaluated.
Croatian: Sigurnost i djelotvornost smanjenih doza, navedenih u dijelu 4.2, temelje se na farmakokinetičkim podacima i modeliranju za jednu dozu i nisu klinički analizirane.
English: If you have advanced HIV disease (AIDS) and another infection, you may develop inflammation or worsening of the symptoms of infection when you start treatment with Emtriva.
Croatian: Ako imate uznapredovalu bolest HIV-a (SIDA) i drugu infekciju, u Vas se mogu nakon započinjanja liječenja Emtrivom razviti upale ili pogoršanje simptoma infekcije.
English: Up to 30% of the emtricitabine dose can be removed by haemodialysis.
Croatian: Hemodijalizom se može ukloniti do 30% doze emtricitabina.
English: Administration of up to 1,200 mg emtricitabine has been associated with the adverse reactions listed above (see section 4.8).
Croatian: Primjena emtricitabina u dozi do 1200 mg povezana je s gore navedenim nuspojavama (vidjeti dio 4.8).
English: The apparent total body clearance at steady-state (CL/F) increased with age over the 3-month period with a corresponding decrease in AUC.
Croatian: Prividni klirens iz cijelog tijela u stanju dinamičke ravnoteže (CL/F) povećavao se s dobi tijekom tromjesečnog razdoblja uz odgovarajuće smanjenje AUC-a.
English: This medicine also contains 480 mg propylene glycol per 24 mL (maximum single dose) which is equivalent to a maximum of 12 mg/kg/day.
Croatian: Ovaj lijek sadrži i 480 mg propilenglikola u 24 mL (maksimalna pojedinačna doza) što odgovara maksimalnom iznosu od 12 mg/kg/dan.
English: Consequently, the use of emtricitabine in combination with lamivudine for the treatment of HIV infection cannot be recommended at this time.
Croatian: Stoga se trenutno ne može preporučiti primjena emtricitabina u kombinaciji s lamivudinom za liječenje infekcije HIV-om.
English: However, based on the minimal metabolism of emtricitabine and the renal route of elimination it is unlikely that a dose adjustment would be required in patients with hepatic insufficiency (see section 5.2).
Croatian: No, s obzirom na minimalni metabolizam emtricitabina i njegovu eliminaciju putem bubrega, malo je vjerojatno da bi u pacijenata s insuficijencijom jetre bilo potrebno prilagođavati dozu (vidjeti dio 5.2).
English: In some patients with advanced liver disease or cirrhosis, stopping treatment is not recommended as this may lead to worsening of hepatitis.
Croatian: U nekih se pacijenata s uznapredovalom bolešću jetre ili cirozom jetre ne preporučuje prekid liječenja, jer to može dovesti do pogoršanja hepatitisa.
English: Before starting treatment, your doctor may order blood tests to assess kidney function and may advise you to take a reduced dose of the oral solution or prescribe Emtriva hard capsules.
Croatian: Prije početka liječenja, liječnik će možda zatražiti krvne pretrage kako bi ocijenio funkciju bubrega te Vam može preporučiti da uzimate manju dozu oralne otopine ili Vam može propisati tvrde kapsule Emtriva.
English: If it's less than an hour since you took Emtriva, take another dose.
Croatian: Ako je prošlo manje od jednog sata od kad ste uzeli Emtrivu, uzmite drugu dozu.
English: Dose or dose interval adjustment is required in all patients with creatinine clearance < 30 mL/min (see sections 4.2, 4.4 and
Croatian: Prilagođavanje doze ili intervala doziranja obavezno je za sve pacijente s klirensom kreatinina < 30 mL/min (vidjeti dijelove 4.2, 4.4 i 5.2).
English: Keep this medicine out of the sight and reach of children.
Croatian: Kako čuvati Emtrivu Lijek čuvajte izvan pogleda i dohvata djece.
English: In the adult studies, 1,039 treatment-naïve and 440 treatment-experienced patients received emtricitabine (n = 814) or comparator medicinal product (n = 665) for 48 weeks in combination with other antiretroviral medicinal products.
Croatian: Tijekom ispitivanja provedenih na odraslima, 1039 pacijenata koji nisu bili prethodno liječeni te 440 pacijenata koji su već liječeni primalo je tijekom 48 tjedana emtricitabin (n = 814) ili usporedni lijek (n = 665) u kombinaciji s drugim antiretrovirusnim lijekovima.
English: Skin discolouration (increased pigmentation): Skin discolouration, manifested by hyperpigmentation mainly on the palms and/or soles, was generally mild, asymptomatic and of little clinical significance.
Croatian: Promjena boje kože (povećana pigmentacija): Promjena boje kože koja se najčešće manifestira hiperpigmentacijom na dlanovima i/ili tabanima uglavnom je bila blaga, bez simptoma i bez veće kliničke važnosti.
English: What Emtriva is and what it is used for Emtriva is a treatment for Human Immunodeficiency Virus (HIV) infection in adults, children and infants aged 4 months and over.
Croatian: Što je Emtriva i za što se koristi Emtriva se primjenjuje za liječenje infekcije virusom humane imunodeficijencije (HIV) u odraslih i dojenčadi u dobi od 4 mjeseca i starije.
English: When deciding on a new regimen for patients who have failed an antiretroviral regimen, careful consideration should be given to the patterns of mutations associated with different medicinal products and the treatment history of the individual patient.
Croatian: Prilikom odlučivanja o novom režimu liječenja pacijenata u kojih antiretrovirusni režim liječenja nije bio uspješan, nužno je pozorno razmotriti uzorke mutacija povezanih s drugim lijekovima i prijašnjim liječenjima pojedinog pacijenta.
English: Warnings and precautions • Tell your doctor if you have had kidney disease, or if tests have shown problems with your kidneys.
Croatian: • Obavijestite liječnika ako ste imali bolest bubrega ili ako su pretrage ukazale na probleme s bubrezima.
English: Emtricitabine is not recommended as monotherapy for the treatment of HIV infection.
Croatian: Ne preporučuje se primjena emtricitabina kao jedinog lijeka za liječenje infekcije HIV-om.
English: Blood and lymphatic system disorders: Common:
Croatian: Poremećaji krvi i limfnog sustava:
English: If you notice signs of inflammation or infection soon after you start taking Emtriva,
Croatian: Ako opazite znakove upale ili infekcije ubrzo nakon početka uzimanja Emtrive, odmah o tome obavijestite liječnika.
English: Patients with liver disease including chronic hepatitis B or C, who are treated with antiretrovirals, have a higher risk of severe and potentially fatal liver complications.
Croatian: Pacijenti s bolešću jetre, uključujući kronični hepatitis B ili C, koji se liječe antiretrovirusnim lijekovima, izloženi su većem riziku od teških i potencijalno fatalnih jetrenih komplikacija.
English: Steady-state trough plasma concentrations reached levels approximately 4-fold above the in vitro IC90 values for anti-HIV activity.
Croatian: Najniže koncentracije u plazmi u stanju dinamičke ravnoteže dostigle su razine koje su otprilike četverostruko iznad in vitro vrijednosti IK90 djelovanja protiv HIV-a.
English: Emtricitabine is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which competitively inhibits HIV-1 reverse transcriptase, resulting in DNA chain termination.
Croatian: Stanični enzimi fosforiliraju emtricitabin u emtricitabin 5'-trifosfat koji kompetitivno inhibira HIV-1 reverznu transkriptazu, što rezultira prekidom lanca DNK.
English: At 48 weeks of treatment the emtricitabine-containing regimen demonstrated an equivalent proportion of patients with HIV RNA < 400 copies/mL (94% emtricitabine versus 92%) and a greater proportion of patients with HIV RNA < 50 copies/mL (95% emtricitabine versus 87%) compared with the patients continuing with their PI-HAART regimen.
Croatian: Nakon 48 tjedana terapije, terapija režimom koji sadrži emtricitabin pokazala je ekvivalentan udio pacijenata s HIV RNK < 400 kopija/mL (94% u skupini emtricitabina naspram 92%) te veći udio pacijenata s HIV RNK < 50 kopija/mL (95% za emtricitabin naspram 87%) u usporedbi s pacijentima koji su nastavili HAART-terapiju inhibitorom proteaze.
English: Emtricitabine did not inhibit in vitro drug metabolism mediated by the following human CYP450 isoenzymes: 1A2, 2A6, 2B6, 2C9, 2C19, 2D6 and 3A4.
Croatian: Emtricitabin nije inhibirao in vitro metabolizam lijeka posredovan sljedećim izoenzimima CYP450 u ljudi: 1A2, 2A6, 2B6, 2C9, 2C19, 2D6 i 3A4.
English: Pharmacokinetic parameters were determined following administration of a single dose of 200 mg emtricitabine hard capsules to 30 non-HIV infected subjects with varying degrees of renal insufficiency.
Croatian: Farmakokinetički parametri određeni su nakon primjene jednokratnih doza od 200 mg emtricitabina, u obliku tvrdih kapsula, u 30 ispitanika koji nisu bili inficirani virusom HIV-a, a imali su različite stupnjeve insuficijencije bubrega.
English: There have been reports of mitochondrial dysfunction in HIV negative infants exposed in utero and/or postnatally to nucleoside analogues; these have predominantly concerned treatment with regimens containing zidovudine.
Croatian: Postoje izvješća o poremećenoj funkciji mitohondrija kod HIV-negativne dojenčadi koja je bila in utero i/ili postnatalno izložena analozima nukleozida, što se pretežno odnosi na liječenje režimima koji su sadržavali zidovudin.
English: Do not stop your treatment without contacting your doctor.
Croatian: Ne prekidajte liječenje bez prethodnog savjetovanja s liječnikom.
English: In HIV infected patients with severe immune deficiency at the time of institution of CART, an inflammatory reaction to asymptomatic or residual opportunistic pathogens may arise and cause serious clinical conditions, or aggravation of symptoms.
Croatian: U pacijenata inficiranih HIV-om s teškom imunodeficijencijom u vrijeme uvođenja CART-a može doći do upalne reakcije na asimptomatske ili rezidualne oportunističke patogene, koja može uzrokovati teška klinička stanja ili pogoršanje simptoma.
English: The following side effects are common (these can affect up to 10 in every 100 patients):
Croatian: Sljedeće nuspojave su česte (mogu se javiti u do 10 na svakih 100 pacijenata):
English: Emtricitabine is primarily excreted via glomerular filtration and active tubular secretion.
Croatian: Emtricitabin se primarno izlučuje glomerularnom filtracijom i aktivnom tubularnom sekrecijom.
English: The safety and efficacy of the dose interval adjustment guidelines provided in section 4.2 are based on single dose pharmacokinetic data and modelling and have not been clinically evaluated.
Croatian: Sigurnost i djelotvornost smjernica za prilagođavanje intervala doziranja navedenih u dijelu 4.2, temelje se na farmakokinetičkim podacima i modeliranju za jednu dozu i nisu klinički analizirane.
English: With the exception of famciclovir and tenofovir disoproxil fumarate, the effect of co-administration of emtricitabine with medicinal products that are excreted by the renal route, or other medicinal products known to affect renal function, has not been evaluated.
Croatian: Izuzev famciklovira i tenofovirdizoproksil fumarata, nije procijenjen učinak istovremene primjene emtricitabina i drugih lijekova koji se luče bubrežnim putem, ili drugih lijekova za koje je poznato da utječu na bubrežnu funkciju.
English: HIV/HBV co-infected patients: The adverse reaction profile in patients co-infected with HBV is similar to that observed in patients infected with HIV without co-infection with HBV.
Croatian: Pacijenti istovremeno inficirani HIV-om i HBV-om: Profil nuspojava u pacijenata s istovremenom infekcijom HBV-om sličan je profilu koji je zapažen u pacijenata zaraženih virusom HIV-a bez istovremene infekcije HBV-om.
English: If you accidentally take too many Emtriva hard capsules, contact your doctor or nearest emergency department for advice.
Croatian: Ako slučajno uzmete previše tvrdih kapsula Emtrive, obratite se svom liječniku ili otiđite po savjet u hitnu službu najbliže bolnice.
English: If the patient vomits more than 1 hour after taking Emtriva they do not need to take another dose.
Croatian: Ako pacijent povraća nakon više od 1 sata od uzimanja Emtrive, nije potrebno uzeti još jednu dozu.
English: Emtricitabine is primarily excreted by the kidneys with complete recovery of the dose achieved in urine (approximately 86%) and faeces (approximately 14%).
Croatian: Emtricitabin se prvenstveno izlučuje putem bubrega pri čemu se čitava doza izolira iz mokraće (oko 86%) i stolice (oko 14%).