FrancophonIA/ELRC3.0 huggingface dataset:
English: Sandimmun 50 mg soft capsules are corn yellow and oblong.
Maltese: Sandimmun 50 mg kapsuli rotob sofor lewn il-qamħ u oblungi.
English: At toxic doses (rats at 30 mg/kg/day and rabbits at 100 mg/kg/day orally), ciclosporin was embryo- and foetotoxic as indicated by increased prenatal and postnatal mortality, and reduced foetal weight together with related skeletal retardations.
Maltese: F'dożi tossiċi (il-firien sa 30 mg/kg/kuljum u l-fniek sa 100 mg/kg/kuljum oralment), ciclosporin kien tossiku għall-embrijun u l-fetu kif deher permezz ta' żieda fil-mortalità ta' qabel u wara t-twelid, u naqqas il-piż tal-fetu flimkien ma' difetti skelettriċi relatati.
English: This is equivalent to nearly 15 ml beer or 5 ml wine.
Maltese: Dan hu daqs bejn wieħed u ieħor 15 ml birra jew 5 ml inbid.
English: The total dose each day is usually between 5 mg and 7 mg per kilogram body weight.
Maltese: Endogenous uveitis - Id-doża totali għal kuljum hi normalment ta' bejn 5 mg u 7 mg għal kull kilo tal-piż tiegħek.
English: Each capsule contains 25 mg ciclosporin.
Maltese: Kull kapsula fiha 25 mg ciclosporin.
English: In refractory cases, the dose can be increased to 7 mg/kg/day for a limited period.
Maltese: F'każijiet refrattorji, id-doża tista' tiżdied għal 7 mg/kg/kuljum għal perjodu limitat.
English: Caution is recommended when co-administering ciclosporin with lercanidipine (see section 4.4).
Maltese: Hu rrakkomandat li wieħed joqgħod attent meta jagħti flimkien ciclosporin ma' lercanidipine (ara sezzjoni 4.4).
English: In all cases of overdosage, general supportive measures should be followed and symptomatic treatment applied.
Maltese: Fil-każijiet kollha ta' doża eċċessiva, wieħed għandu jipprovdi miżuri supportivi ġenerali u jkun hemm trattament sintomatiku.
English: Co-administration of bosentan and ciclosporin in healthy volunteers increases the bosentan exposure several-fold and there was a 35% decrease in ciclosporin exposure.
Maltese: L-għoti flimkien ta' bosentan u ciclosporin f'voluntiera b'saħħithom żied l-espożizzjoni ta' bosentan għal bosta drabi u kien hemm tnaqqis ta' 35% fl-espożizzjoni ta' ciclosporin.
English: Ciclosporin is an inhibitor of CYP3A4, the multidrug efflux transporter P-glycoprotein and organic anion transporter proteins (OATP) and may increase plasma levels of co-medications that are substrates of this enzyme and/or transporter.
Maltese: Ciclosporin hu inibitur ta' CYP3A4, it-trasportatur tal-efluss tal-multimediċina glikoproteina-P u lproteini trasportaturi tal-anjon organiku (OATP) u jistgħu jgħollu l-livelli tal-plażma meta jingħataw mediċini flimkien li huma sottostrati u/jew trasportaturi ta' din l-enzima.
English: Medicines which may increase the level of ciclosporin in your blood include: antibiotics (such as erythromycin or azythromycin), anti-fungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, nicardipine, verapamil, amiodarone), metoclopramide (used to stop sickness), oral contraceptives, danazol (used to treat menstrual problems), medicines used to treat gout (allopurinol), cholic acid and derivatives (used to treat gallstones), protease inhibitors used to treat HIV, imatinib (used to treat leukaemia or tumours), colchicine, telaprevir (used to treat hepatitis C).
Maltese: Mediċini li jistgħu jżidu l-livell ta' ciclosporin fid-demm tiegħek jinkludu: antibjotiċi (bħal erythromycin jew azythromycin), antifungali (voriconazole, itraconazole), mediċini użati għal problem tal-qalb jew pressjoni għolja tad-demm (diltiazem, nicardipine, verapamil, amiodarone), metoclopramide (użat biex iwaqqaf id-dardir), kontraċettvi orali, danazol (użat biex jittratta problemi menstruwali), mediċini użati biex jikkuraw il-gotta (allopurinol), aċidi koliċi u derivattivi (użati biex jittrattaw il-ġebla), inibituri protease użati biex tkun ittrattata l-HIV, imatinib (użat biex jikkukra l-lewċemija jew it-tumuri), colchicine, telaprevir (użat biex jittratta l-epatite Ċ).
English: Sandimmun may also cause dose-dependent, reversible increases in serum bilirubin and in liver enzymes (see section 4.8).
Maltese: Sandimmun jista' wkoll jikkawża żidiet riversibbli dipendenti fuq id-doża fil-bilirubin tas-serum u flenzimi tal-fwied (ara sezzjoni 4.8).
English: If plasma or serum is used, a standard separation protocol (time and temperature) should be followed.
Maltese: Jekk jintuża l-plażma jew is-serum, wieħed għandu jimxi ma' protokoll ta' separazzjoni standard (ħin u temperatura).
English: o Capsule shell: Iron oxide yellow (E172), titanium dioxide (E171), glycerol 85%, sorbitol syrup special, gelatin.
Maltese: Iron oxide yellow (E172), titanium dioxide (E171), glycerol 85%, sorbitol syrup special, gelatin.
English: Owing to its possible interference with the cytochrome P450 enzyme system, grapefruit juice should be avoided for dilution (see section 4.5).
Maltese: Minħabba l-interferenza li jista' jkun hemm mas-sistema tal-enzimi taċċitokromu P450, wieħed għandu jevita li jħallatha ma' meraq tat-tronġa (ara sezzjoni 4.5).
English: Atopic dermatitis
Maltese: Dermatite atopika
English: Amiodarone substantially increases the plasma ciclosporin concentration concurrently with an increase in serum creatinine.
Maltese: Amiodarone iżid sostanzjalement il-konċentrazzjoni ta' ciclosporin fil-plażma flimkien ma' żieda filkreatinina tas-serum.
English: Pre-existing infections may also be aggravated and reactivation of polyomavirus infections may lead to polyomavirus-associated nephropathy (PVAN) or to JC virus associated progressive multifocal leukopathy (PML).
Maltese: Infezzjonijiet eżistenti diġà jistgħu wkoll jaggravaw u riattivazzjoni ta' infezzjonijiet poliomavirus jistgħu jwasslu għal nefropatija assoċjata ma' poliomavirus (PVAN) jew għal lewkopatija multifokali progressiva assoċjata mal-virus JC (PML).
English: Each capsule contains 100 mg ciclosporin.
Maltese: Kull kapsula fiha 100 mg ciclosporin.
English: Sandimmun concentrate for solution for infusion contains macrogolglycerol ricinoleate/polyethoxylated castor oil, which can cause phathalate stripping from polyvinyl chloride.
Maltese: Sandimmun konċentrat għal soluzzjoni għall-infużjoni fih macrogolglycerol ricinoleate/polyethoxylated castor oil, li jistgħu jikkawżaw tqaxxir ftalati li jiġi mill-kloru tal-polivinil.
English: o Capsule shell: Iron oxide red (E172), titanium dioxide (E 171), glycerol 85%, sorbitol syrup special, gelatin.
Maltese: Iron oxide red (E172), titanium dioxide (E 171), glycerol 85%, sorbitol syrup special, gelatin.
English: If a significant impairment of renal function occurs, the dosage of the co-administered medicinal product should be reduced or alternative treatment considered.
Maltese: Jekk ikun hemm indeboliment qawwi tal-funzjoni tal-kliewi, id-doża talprodott mediċinali mogħti fl-istess ħin għandha titnaqqas jew jitqies trattament alternattiv.
English: In the 78-week mouse study, at doses of 1, 4, and 16 mg/kg/day, evidence of a statistically significant trend was found for lymphocytic lymphomas in females, and the incidence of hepatocellular carcinomas in mid-dose males significantly exceeded the control value.
Maltese: Fi studju fuq il-ġrieden li dam għaddej 78 ġimgħa, b'dożi ta' 1. 4, u 16 mg/kg/kuljum, instab li kien hemm evidenza ta' tendenza sinjifikanti statistikament ta' limfomi limfoċiti fin-nisa, u l-inċidenza ta' karċinomi epatoċellulari flirġiel mogħtija nofs id-doża qabżet b'qawwa il-valur ta' kontroll.
English: Exposure changes of commonly used statins with ciclosporin are summarised in Table 1.
Maltese: Qed jingħata sommarju tat-tibdiliet fl-espożizzjoni ta' statini użati komunament ma' ciclosporin f'Tabella 1.
English: Ensure that the correct amount of medicine is in the syringe.
Maltese: Jista' jkun hemm kemm infezzjonijiet ġenerali u wkoll lokalizzati.
English: Caution should be observed when co-administering ciclosporin with drugs that substantially increase or decrease ciclosporin plasma concentrations, through inhibition or induction of CYP3A4 and/or Pglycoprotein (see section 4.5).
Maltese: Wieħed għandu joqgħod attent meta jagħti ciclosporin flimkien ma' mediċini li jżidu jew inaqqsu sostanzjalment il-konċentrazzjonijiet tal-plażma, permezz ta' inibizzjoni jew induzzjoni ta' CYP3A4 u/jew glikoproteina-P (ara sezzjoni 4.5).
English: • your blood pressure before the start of your treatment and regularly during treatment,
Maltese: • il-pressjoni tad-demm qabel ma tibda t-trattament tiegħek u b'mod regolari waqt it-trattament,
English: Each capsule contains 50 mg ciclosporin.
Maltese: Kull kapsula fiha 50 mg ciclosporin.
English: NAME OF THE MEDICINAL PRODUCT Sandimmun and associated names (see Annex I) 25 mg soft capsules Sandimmun and associated names (see Annex I) 50 mg soft capsules Sandimmun and associated names (see Annex I) 100 mg soft capsules [See Annex I - To be completed nationally] Ciclosporin
Maltese: Sandimmun u ismijiet assoċjati (Ara Anness I) 25 mg kapsuli rotob Sandimmun u ismijiet assoċjati (Ara Anness I) 50 mg kapsuli rotob Sandimmun u ismijiet assoċjati (Ara Anness I) 100 mg kapsuli rotob [Ara Anness I - Biex timtela mill-pajjiż partikolari]
English: When Sandimmun is given with other immunosuppressants (e.g. with corticosteroids or as part of a triple or quadruple medicinal product therapy), lower doses (e.g. 3 to 6 mg/kg given in 2 divided doses for the initial treatment) may be used.
Maltese: Meta Sandimmun jingħata ma' immunosuppressanti oħrajn (eż. ma' kortikosterojdi jew bħala parti minn terapija bi tliet jew erba' prodotti mediċinali), jistgħu jintużaw dożi aktar baxxi (eż. 3 sa 6 mg/kg mogħtija f'żewġ dożi separati għat-trattament inizjali).
English: This contains 5 mg of ciclosporin.
Maltese: Din fiha 5 mg ciclosporin.
English: There is a high variability in the data reported on the terminal elimination half-life of ciclosporin, depending on the assay applied and the target population.
Maltese: Hemm varjabbiltà qawwija fid-dejta rrappurtata dwar l-eliminazzjoni tal-half-life terminali ta' ciclosporin, u dan jiddependi mill-eżami applikat u l-popolazzjoni mmirata.
English: Some malignancies may be fatal.
Maltese: Xi tumuri malinni jistgħu jkunu fatali.
English: If there is no alternative, it is recommended to closely monitor blood levels of ciclosporin, renal function, and for side effects of ciclosporin.
Maltese: Jekk m'hemmx alternattiva, hu rrakkomandat li tevalwa mill-qrib il-livelli ta' ciclosporin fid-demm, il-funzjoni tal-kliewi, u l-effetti sekondarji ta' ciclosporin.
English: If your doctor switches you from one oral formulation of ciclosporin to another After you change from one oral formulation of ciclosporin to another:
Maltese: Jekk it-tabib tiegħek jaqilbek minn formulazzjoni orali għal oħra ta' ciclosporin Wara li taqleb minn formulazzjoni orali waħda ta' ciclosporin għal oħra:
English: Cases of acute nephrotoxicity reported disorders of ion homeostasis, such as hyperkalaemia, hypomagnesaemia, and hyperuricaemia.
Maltese: Każijiet ta' nefrotossiċità rrappurtaw disturbi ta' omeostasi jonika, bħal iperkalemija, ipomagneżemija, u iperurikemija.
English: • if you are breast-feeding.
Maltese: • Tkabbir eċċessiv ta' pil.
English: Special excipients: Polyoxyl 40 hydrogenated castor oil Sandimmun contains polyoxyl 40 hydrogenated castor oil, which may cause stomach upsets and diarrhoea.
Maltese: Żejt ir-riġnu idroġenat polyoxyl 40 Sandimmun fih żejt ir-riġnu u idroġenat polyoxyl 40, li jista' jikkawża dwejjaq fl-istonku u dijarrea.
English: This is because this medicine contains alcohol (see section below “Sandimmun conatins castor oil and ethanol”).
Maltese: Dan għaliex din il-mediċina fiha l-alkoħol (ara s-sezzjoni ta' hawn taħt, “Sandimmun fih castor oil u ethanol”).
English: Doses available Fold change in exposure with ciclosporin
Maltese: Bidla bejn formulazzjonijiet orali ta' ciclosporin
English: All inducers of CYP3A4 and/or P-glycoprotein are expected to decrease ciclosporin levels.
Maltese: L-indutturi kollha ta' CYP3A4 u/jew tal-glikoproteina-P huma mistennija li jnaqqsu l-livelli ta' ciclosporin.
English: The 4-ml syringe is used to measure doses greater than 1 ml and up to 4 ml (each graduation of 0.1 ml corresponds to 10 mg of ciclosporin).
Maltese: Is-seringa ta' 4 ml tintuża biex jitkejlu d-dożi ta' aktar minn ml 1 u sa 4 ml (kull gradwazzjoni ta' 0.1 ml tikkorrispondi għal 10 mg ciclosporin).
English: Excipient with known effect:
Maltese: Effetti sekondarji rari ħafna:
English: In patients with nephrotic syndrome treated with immunosuppressants (including ciclosporin), the occurrence of malignancies (including Hodgkin's lymphoma) has occasionally been reported.
Maltese: F'pazjenti b'sindrome nefrotiku ttrattati b'immunosuppressanti (inkluż ciclosporin), dehru xi drabi tumuri malinni (inkluż tal-limfoma ta' Hodgkin).
English: This contains 10 mg of ciclosporin.
Maltese: Dan fih 10 mg ciclosporin.
English: The elimination half-life in kidney-transplanted patients was approximately 11 hours, with a range between 4 and 25 hours.
Maltese: L-eliminazzjoni tal-half-life f'pazjenti bi trapjant tal-kliewi kienet ta' madwar 11-il siegħa, b'medda ta' bejn 4 u 25 siegħa.
English: Hirsutism
Maltese: Pożoloġija
English: Activation of latent polyomavirus infections that may lead to polyomavirus associated nephropathy (PVAN), especially to BK virus nephropathy (BKVN), or to JC virus associated progressive multifocal leukoencephalopathy (PML), have been observed in patients receiving ciclosporin.
Maltese: F'pazjenti mogħtija ciclosporin kienu osservati attivazzjonijiet ta' infezzjonijiet tat-tip poliomavirus rieqda li jistgħu jwasslu għal nefrapatija assoċjata ma' poliomavirus (PVAN), b'mod speċjali ma' nefropatija bil-virus BK (BKVN), jew għall-virus JC assoċjat ma' lewkoenċefalopatija multifokali progressiva (PML).
English: Elevations in serum creatinine were observed in the studies using everolimus or sirolimus in combination with full-dose ciclosporin for microemulsion.
Maltese: Kien hemm żidiet fil-kreatinina tas-serum waqt studji li użaw everolimus jew sirolimus flimkien ma' doża sħiħa ta' ciclosporin għal mikroemulsjoni.
English: In a study performed in severe liver disease patients with biopsy-proven cirrhosis, the terminal half-life was 20.4 hours (range between 10.8 to 48.0 hours) compared to 7.4 to 11.0 hours in healthy subjects.
Maltese: Fi studju mwettaq fost pazjenti b'mard tal-fwied gravi b'ċirrożi ppruvata b'bijopsija, il-half life terminali kien ta' 20.4 sigħat (medda ta' bejn 10.
English: All metabolites identified so far contain the intact peptide structure of the parent compound; some possess weak immunosuppressive activity (up to one-tenth that of the unchanged drug).
Maltese: Il metaboliti kollha identifikati s'issa fihom l-istruttura peptide intatta tal-komponenti parentali; uħudgħandhom attività immunosuppressiva dgħajfa (sa wieħed minn kull għaxra tal-mediċina mhux mibdula).
English: Following concomitant administration of ciclosporin and aliskiren, a P-gp substrate, the Cmax of aliskiren was increased approximately 2.5-fold and the AUC approximately 5-fold.
Maltese: Wara l-għoti flimkien ta' ciclosporin u aliskiren, sottostrat ta' P-gp, is-Cmax ta' aliskiren żdied b'madwar 2.5 drabi u l-AUC b'madwar 5 drabi.
English: Other medicines and Sandimmun
Maltese: Kif ser jintuża Sandimmun
English: Stomach ulcer.
Maltese: Mhux applikabbli.
English: However, the pharmacokinetic profile of ciclosporin was not significantly altered.
Maltese: Madanakollu, il-profil farmakokinetiku ta' ciclosporin ma tibiddilx b'mod qawwi.
English: NAME OF THE MEDICINAL PRODUCT Sandimmun and associated names (see Annex I) 100 mg/ml oral solution [See Annex I - To be completed nationally] Ciclosporin
Maltese: Sandimmun u ismijiet assoċjati (ara Anness I) 100 mg/ml soluzzjoni orali [Ara Anness I - Biex timtela mill-pajjiż partikolari] Ciclosporin
English: The total dose each day is usually between 2.5 mg per kilogram of your body weight and 5 mg per kilogram body weight.
Maltese: Psorjasi u dermatite atopika - Id-doża totali għal kuljum hi normalment ta' bejn 2.5 mg għal kull kilo tal-piż tiegħek u 5 mg għal kull kilo tal-piż tiegħek.
English: Haemolytic uraemic syndrome, microangiopathic haemolytic anaemia
Maltese: IL-PRODOTTI MEDIĊINALI, JEKK HEMM BŻONN.
English: Nephrotic syndrome For inducing remission, the recommended daily dose is given in 2 divided oral doses.
Maltese: Sindrome nefrotiku Sabiex ikun hemm remissjoni, id-doża rrakkomandata għal kuljum tingħata f'2 dożi orali separati.
English: Capsule shell Iron oxide red (E172) Titanium dioxide (E 171) Glycerol 85% Sorbitol syrup special Gelatin
Maltese: Il-kisja tal-kapsula Iron oxide red (E172) Titanium dioxide (E 171) Glycerol 85% Sorbitol syrup special Gelatin
English: In 9 liver transplant patients aged 0.65-6 years, clearance was 9.3±5.4 ml/min/kg (assay: HPLC).
Maltese: F'9 pazjenti bi trapjant li għandhom bejn 0.6 u 5.6 snin, it-tneħħija kienet ta' 9.
English: Preference should be given to an antihypertensive agent that does not interfere with the pharmacokinetics of ciclosporin, e.g. isradipine (see section 4.5).
Maltese: Għandha tingħata preferenza lil aġent għal kontra l-pressjoni għolja li ma jinterferixxix mal-farmakokinetiċi ta' ciclosporin, eż. isradipine (ara sezzjoni 4.5).
English: Swallow the capsules whole with water.
Maltese: Ibla' l-kapsuli sħaħ mal-ilma.
English: PHARMACEUTICAL FORM AND CONTENTS Oral solution containing 100 mg ciclosporin per mL
Maltese: U KONTENUT Soluzzjoni orali li fiha 100 mg ciclosporin għal kull mL
English: • Loss of appetite.
Maltese: • Nuqqas ta' aptit.
English: Capsule shell Iron oxide red (E172) Titanium dioxide (E171) Glycerol 85% Sorbitol syrup special Gelatin
Maltese: Il-kisja tal-kapsula Iron oxide red (E172) Titanium dioxide (E171) Glycerol 85% Sorbitol syrup special Gelatin
English: Psoriasis and atopic dermatitis
Maltese: Antibjotiċi azole:
English: Myalgia, muscle cramps
Maltese: OĦRA, JEKK MEĦTIEĠA
English: Organ, bone marrow and stem cell transplantation The total dose each day is usually between 2 mg and 15 mg per kilogram body weight.
Maltese: Trapjantazzjoni tal-organi, tal-mudullun jew taċ-ċelluli staminali - Id-doża totali għal kuljum hi normalment ta' bejn 2 mg u 15 mg għal kull kilo tal-piż tiegħek.
English: Effective pre-emptive and therapeutic strategies should be employed, particularly in patients on multiple long-term immunosuppressive therapy.
Maltese: Għandhom jitħaddmu strateġiji preventivi u terapewtiċi effettivi, b'mod partikulari f'pazjenti fuq terapija immunosuppressiva multipla fit-tul.
English: The frequency of malignancies increases with the intensity and duration of therapy (see section 4.4).
Maltese: Il-frekwenza tat-tumuri malinni tiżdied mal-intensità u ddewmien tat-terapija (ara sezzjoni 4.4).
English: Ciclosporin is extensively metabolised by the liver.
Maltese: Ciclosporin jiġi mmetabolizzat b'mod estensiv mill-fwied.
English: Each mark on the syringe is 0.05
Maltese: Kull marka fis-seringa hi 0.05 ml.
English: • Medicines which may affect your kidneys.
Maltese: • jekk din il-mediċina qed tingħata lil tfal żgħar.
English: Ciclosporin may increase the plasma concentrations of repaglinide and thereby increase the risk of hypoglycaemia.
Maltese: Ciclosporin jista' jżid il-konċentrazzjonijiet ta' repaglinide fil-plasma u għaldaqstant iżid ir-riskju ta' ipogliċemija.
English: • Brain problems with signs such as seizures, confusion, feeling disorientated, being less responsive, personality changes, feeling agitated, sleeplessness, changes to your sight, blindness, coma, paralysis of part or all of the body, stiff neck, loss of coordination with or without unusual speech or eye movements.
Maltese: • Problemi tal-moħħ b'sinjali bħal aċċessjonijiet, konfużjoni, tħossok mitluf, tirreaġixxi anqas, tibdiliet fil-personalità, tħossok aġitat, nuqqas ta' rqad, tibdiliet fil-vista tiegħek, għama, koma, paraliżi ta' parti minn ġismek jew kollu, għonq iebes, nuqqas ta' koordinazzjoni b'taħdit u movimenti tal-għajn li mhumiex tas-soltu, jew mingħajrhom.
English: The principal adverse reactions observed in clinical trials and associated with the administration of ciclosporin include renal dysfunction, tremor, hirsutism, hypertension, diarrhoea, anorexia, nausea and vomiting.
Maltese: Ir-reazzjonijiet avversi prinċipali osservati waqt il-provi kliniċi u assoċjati mal-għoti ta' ciclosporin jinkludu disfunzjoni tal-kliewi, tregħid, irsutiżmu, pressjoni għolja, dijarrea, anoressija, dardir u rimettar.
English: This is used to treat tumours, severe psoriasis and severe rheumatoid arthritis.
Maltese: Dan jintuża biex jikkura tumuri, psorajsi gravi u artrite rewmatojde gravi.
English: In some patients, GVHD occurs after discontinuation of ciclosporin treatment, but usually responds favourably to re-introduction of therapy.
Maltese: F'xi pazjenti, ikun hemm GVHD wara li jitwaqqaf it-trattament b'ciclosporin, imma normalment jirrispondu tajjeb meta terġa' tibda tintuża t-terapija.
English: Each ampoule of 1 ml contains 50 mg of ciclosporin.
Maltese: Kull kunjett ta' 1 ml fih 50 mg ciclosporin.
English: LABELLING
Maltese: LISTA
English: Like other immunosuppressants, ciclosporin predisposes patients to the development of a variety of bacterial, fungal, parasitic and viral infections, often with opportunistic pathogens.
Maltese: Bħal immunosuppressanti oħrajn, ciclosporin iwassal lill-pazjenti biex jiżviluppaw varjetà ta' infezzjonijiet batteriċi, fungali, parasitiċi u virali, ħafna drabi b'patoġeni opportunistiċi.
English: There have been solicited and spontaneous reports of hepatotoxicity and liver injury including cholestasis, jaundice, hepatitis and liver failure in patients treated with ciclosporin.
Maltese: Kien hemm rapporti mitluba u spontanji dwar epatossiċità u ħsara fil-fwied inkluż kolestasi, suffejra, epatite u disfunzjoni tal-fwied f'pazjenti ttrattati b'ciclosporin.
English: Capsule shell Iron oxide yellow (E172) Titanium dioxide (E171) Glycerol 85% Sorbitol syrup special Gelatin
Maltese: Il-kisja tal-kapsula Iron oxide black (E172) Titanium dioxide (E171) Glycerol 85% Sorbitol syrup special Gelatin
English: If eGFR decreases by more than 25% below baseline at more than one measurement, the dosage of Sandimmun should be reduced by 25 to 50%.
Maltese: Jekk l-eGFR tonqos b'aktar minn 25% taħt il-linja bażi f'aktar minn kejl wieħed, id-doża mogħtija ta' Sandimmun għandha titnaqqas b'25 sa 50%.
English: In very severe cases, rapid and adequate control of the disease is more likely to occur with a starting dose of 5 mg/kg/day.
Maltese: F'każijiet mill-aktar gravi, jista' jkun hemm kontroll rapidu u xieraq tal-marda b'doża inizjali ta' 5mg/kg/kuljum.
English: Macrolide antibiotics: Erythromycin can increase ciclosporin exposure 4- to 7-fold, sometimes resulting in nephrotoxicity.
Maltese: Erythromycin jista' jżid l-espożizzjoni ta' ciclosporin minn 4 għal 7 darbiet, kultant iwassal għal nefrotossiċità.
English: {Name and address} {tel} {fax}
Maltese: {Isem u indirizz} {telefon}
English: • The other ingredients are ethanol anhydrous, maize oil interesterified, maize oil refined.
Maltese: • L-ingredjenti l-oħrajn huma ethanol anhydrous, maize oil interesterified, maize oil refined.
English: Uncoloured glass (type I) ampoule.
Maltese: jew bosentan u aliskiren (użati biex inaqqsu l-pressjoni għolja).
English: Examples are:
Maltese: Teħux Sandimmun: