FrancophonIA/ELRC3.0 huggingface dataset:
English: Studies in dogs found that SevoFlo was as effective at starting and maintaining anaesthesia as other anaesthetic agents, such as isoflurane (another anaesthetic gas), thiopental, propofol, and ketamine plus diazepam.
Slovenian: Študije pri psih so pokazale, da je zdravilo SevoFlo pri povzročitvi in vzdrževanju anestezije enako učinkovito kot nekateri drugi anestetiki, npr. izofluran (drug plin za anestezijo), tiopental, propofol in ketamin z diazepamom.
English: SevoFlo received a marketing authorisation valid throughout the EU for SevoFlo on 11 December
Slovenian: Zdravilo SevoFlo je pridobilo dovoljenje za promet, veljavno po vsej Evropski uniji, 11. decembra 2002.
English: For more information about using SevoFlo, see the package leaflet or contact your veterinarian or pharmacist.
Slovenian: Za več informacij glede uporabe zdravila SevoFlo glejte navodilo za uporabo ali se posvetujte z veterinarjem ali farmacevtom.
English: It contains the active substance sevoflurane, a chemical which is a liquid at room temperature, but when heated becomes a gas (vaporises).
Slovenian: Zdravilo vsebuje učinkovino sevofluran, tj. kemično snov, ki je pri sobni temperaturi tekoča, pri segrevanju pa se uplini (upari).
English: Safety information has been included in the summary of product characteristics and the package leaflet for SevoFlo, including the appropriate precautions to be followed by healthcare professionals and animal owners or keepers.
Slovenian: V povzetek glavnih značilnosti zdravila SevoFlo in navodilo za njegovo uporabo so bile vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in lastniki ali skrbniki živali.
English: SevoFlo is used to bring about and maintain general anaesthesia (loss of consciousness).
Slovenian: Uporablja se za povzročitev in vzdrževanje splošne anestezije (izgube zavesti).
English: For the full list of side effects of SevoFlo, and for the full list of restrictions, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila SevoFlo, in seznam omejitev glejte navodilo za uporabo.
English: SevoFlo produced a relatively rapid and smooth start of anaesthesia in dogs, followed by a good recovery.
Slovenian: Zdravilo SevoFlo je dokaj hitro in brez težav uvedlo anestezijo pri psih, temu pa je sledilo uspešno prebujanje.
English: For cats, a review of published scientific literature showed that SevoFlo is effective for anaesthesia and that it is compatible with a range of sedative and pain-relieving medicines used in anaesthesia.
Slovenian: Pri mačkah je pregled objavljene znanstvene literature pokazal, da je zdravilo SevoFlo učinkovito kot anestetik ter da se lahko med anestezijo uporablja v kombinaciji z vrsto drugih sedativov in zdravil za lajšanje bolečine.
English: Studies showed that sevoflurane could be used safely with several other medicines commonly used in dogs before or during operations, for maintenance of anaesthesia.
Slovenian: Študije so pokazale, da se lahko sevofluran za vzdrževanje anestezije varno uporablja skupaj s številnimi drugimi zdravili, ki se običajno uporabljajo pri psih pred ali med kirurškim posegom.
English: How does SevoFlo work?
Slovenian: Kako zdravilo SevoFlo deluje?
English: How is SevoFlo used?
Slovenian: Kako se zdravilo SevoFlo uporablja?
English: Animal studies are insufficient.
Slovenian: Študij na živalih ni dovolj.
English: Austria, Belgium, Cyprus, Czech Republic, Estonia, Germany, Greece, Finland, Hungary, Iceland, Ireland, Luxembourg, The Netherlands, Norway, Slovakia, Slovenia, Spain, Sweden
Slovenian: Avstrija, Belgija, Ciper, Češka, Estonija, Nemčija, Grčija, Finska, Madžarska, Islandija, Irska, Luksemburg, Nizozemska, Norveška, Slovaška, Slovenija, Španija, Švedska
English: France, Portugal
Slovenian: Francija, Portugalska
English: It has no agonist activity.
Slovenian: Agonističnega delovanja nima.
English: Sugar in your urine.
Slovenian: • Sladkor v urinu.
English: Concomitant intake of food increases the absorption by approximately 15%.
Slovenian: Sočasno uživanje hrane poveča absorpcijo za približno 15 %.
English: you have ever had allergy or asthma.
Slovenian: - če ste kdaj imeli alergijo ali astmo.
English: If this happens to you, do not drive or use any tools or machines.
Slovenian: Če se vam to zgodi, ne vozite in ne upravljajte vozil ali strojev.
English: Medicines to treat cancer.
Slovenian: • Zdravila za zdravljenje raka.
English: A similar effect has also been reported with AIIRAs.
Slovenian: O podobnem učinku so poročali pri ARAII.
English: It is used for treating high blood pressure (hypertension) in adult patients.
Slovenian: Uporablja se za zdravljenje visokega krvnega tlaka (hipertenzije) pri odraslih bolnikih.
English: This causes moderate to severe pain in the stomach.
Slovenian: To povzroči zmerne do hude bolečine v trebuhu.
English: This medicinal product is authorised in the Member States of the EEA under the following names:
Slovenian: To zdravilo je odobreno v državah članicah EGP pod naslednjimi imeni: Ime zdravila
English: Detailed information on this medicinal product is available on the website of {name of MS/Agency}
Slovenian: Podrobne informacije o zdravilu so objavljene na spletni strani {ime DČ/agencije}
English: Taking Atacand Plus with food and drink (in particular alcohol)
Slovenian: Jemanje zdravila Atacand Plus skupaj s hrano in pijačo (še zlasti z alkoholom)
English: Approximately 70% of an oral dose is eliminated in the urine within 48 hours.
Slovenian: Približno 70 % peroralnega odmerka se izloči v urinu v 48 urah.
English: Labelling
Slovenian: OZNAČEVANJE
English: Penicillin (an antibiotic).
Slovenian: • Penicilin (antibiotik).
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS Non-Perforated calendar foil (7, 14, 28, 56 and 98 tablets)
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA PRETISNEM OMOTU Neperforiran koledarski trak (7, 14, 28, 56 in 98 tablet)
English: Atacand Plus is indicated for the:
Slovenian: Zdravilo Atacand Plus je indicirano za:
English: you are allergic to sulphonamide medicines.
Slovenian: - če ste alergični na sulfonamidna zdravila.
English: Pituitary hormone (ACTH).
Slovenian: • Hipofizni hormon (ACTH).
English: The frequencies used in the tables throughout section 4.8 are: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare
Slovenian: Pogostnosti, uporabljane v preglednicah v celotnem poglavju 4.8, so: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000).
English: Available interaction studies indicate no effect on CYP2C9 and CYP3A4.
Slovenian: Študije medsebojnega delovanja, ki so na voljo, ne kažejo vpliva na CYP2C9 in CYP3A4.
English: If a photosensitivity reaction occurs, it is recommended to stop treatment.
Slovenian: Če se pojavi fotosenzibilnostna reakcija, je zdravljenje priporočljivo končati.
English: Dose adjustment of antidiabetic medicinal products, including insulin, may be required.
Slovenian: Potrebna je lahko prilagoditev odmerka antidiabetičnih zdravil, vključno z insulinom.
English: Most of the antihypertensive effect is usually attained within 4 weeks of initiation of treatment.
Slovenian: Večina antihipertenzivnega učinka je po navadi dosežena v 4 tednih po začetku zdravljenja.
English: The safety and efficacy of Atacand Plus in children aged between birth and 18 years have not been established.
Slovenian: Varnost in učinkovitost zdravila Atacand Plus pri otrocih od rojstva do 18. leta starosti nista ugotovljeni.
English: Epidemiological evidence regarding the risk of teratogenicity following exposure to ACE inhibitors during the first trimester of pregnancy has not been conclusive; however a small increase in risk cannot be excluded.
Slovenian: Epidemiološki izsledki o tveganju teratogenih učinkov po izpostavljenosti zaviralcem ACE v prvem trimesečju nosečnosti niso dokončni, toda majhnega povečanja tveganja ni mogoče izključiti.
English: you have ever had gout.
Slovenian: - če ste kdaj imeli protin.
English: There is limited experience with hydrochlorothiazide during pregnancy, especially during the first trimester.
Slovenian: Izkušenj s hidroklorotiazidom med nosečnostjo je malo, še zlasti v prvem trimesečju.
English: Barbiturates (a type of sedative also used to treat epilepsy).
Slovenian: • Barbiturate (vrsto pomirjeval, ki se uporabljajo tudi za zdravljenje epilepsije).
English: Hydrochlorothiazide should not be used for essential hypertension in pregnant women except in rare situations where no other treatment could be used.
Slovenian: Hidroklorotiazida ne smemo uporabljati za zdravljenje esencialne hipertenzije pri nosečnicah, razen v redkih primerih, ko ne moremo uporabiti nobenega drugega zdravljenja.
English: Medicines for diabetes (tablets or insulin).
Slovenian: • Zdravila za sladkorno bolezen (tablete ali insulin).
English: With continuous treatment, most of the reduction in blood pressure is attained within four weeks and is sustained during long-term treatment.
Slovenian: Med stalnim zdravljenjem je večina znižanja krvnega tlaka dosežena v štirih tednih in se med dolgotrajnim zdravljenjem ohrani.
English: The recommended dose of Atacand Plus is one tablet once daily.
Slovenian: Priporočeni odmerek zdravila Atacand Plus je ena tableta enkrat na dan.
English: severe itching of the skin (with raised lumps).
Slovenian: • močno srbenje kože (z dvignjenimi kožnimi spremembami).
English: Large clinical studies have shown that long-term treatment with hydrochlorothiazide reduces the risk for cardiovascular morbidity and mortality.
Slovenian: Velike klinične študije so pokazale, da dolgotrajno zdravljenje s hidroklorotiazidom zmanjša tveganje kardiovaskularne umrljivosti in obolevnosti.
English: The apparent volume of distribution is approximately 0.8 l/kg.
Slovenian: Navidezni volumen porazdelitve je približno 0,8 l/kg.
English: It also has a role in the pathogenesis of organ hypertrophy and end organ damage.
Slovenian: Vlogo ima tudi pri patogenezi hipertrofije in okvare končnih organov.
English: Atacand Plus may cause a reduction in number of white blood cells.
Slovenian: Zdravilo Atacand Plus lahko povzroči zmanjšanje števila belih krvnih celic.
English: Therefore do not stop taking Atacand Plus without first talking to your doctor.
Slovenian: Zato ne nehajte jemati zdravila Atacand Plus, ne da bi se prej posvetovali s svojim zdravnikom.
English: Acetylsalicylic acid (if you are taking more than 3 g each day) (medicine to relieve pain and inflammation).
Slovenian: • Acetilsalicilno kislino (če jo jemljete več kot 3 g na dan) (zdravilo za lajšanje bolečin in ublažitev vnetja).
English: If you have been told by doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Slovenian: Če vam je zdravnik povedal, da imate intoleranco za nekatere sladkorje, se z njim posvetujte, preden vzamete to zdravilo.
English: Cyclosporine, a medicine used for organ transplant to avoid organ rejection.
Slovenian: • Ciklosporin, zdravilo, ki se uporablja za preprečevanje zavrnitve po presaditvi organa.
English: There was no evidence that either compound is carcinogenic.
Slovenian: Ni znakov, da bi bila ena ali druga spojina kancerogena.
English: you have a disease of the adrenal gland called Conn's syndrome (also called primary hyperaldosteronism).
Slovenian: - če imate bolezen nadledvičnih žlez, imenovano Connov sindrom (imenujemo jo tudi primarni hiperaldosteronizem).
English: These changes were considered to be caused by the pharmacological action of candesartan and to be of little clinical relevance.
Slovenian: Te spremembe so ocenili za posledice farmakološkega delovanja kandesartana in za klinično malo pomembne.
English: If you are not sure if this applies to you, please ask your doctor.
Slovenian: Če niste prepričani, ali to velja za vas, se posvetujte z zdravnikom.
English: Your doctor may occasionally do blood tests to check whether Atacand Plus has had any effect on your blood (agranulocytosis).
Slovenian: Zdravnik vas bo morda občasno opravil preiskavo krvi, da bo preveril, ali vam zdravilo Atacand Plus kaj vpliva na kri (agranulocitoza).
English: Serum electrolyte and acid balance should be checked and corrected, if needed.
Slovenian: Kontrolirati je treba elektrolite v serumu in acido-bazno ravnovesje ter jih korigirati, če je treba.
English: Important information about some of the ingredients of Atacand Plus Atacand Plus contains lactose which is a type of sugar.
Slovenian: Pomembne informacije o nekaterih sestavinah zdravila Atacand Plus Zdravilo Atacand Plus vsebujejo laktozo, ki je vrsta sladkorja.
English: Candesartan does not influence ACE or other enzyme systems usually associated with the use of ACE inhibitors.
Slovenian: Kandesartan ne vpliva na ACE ali druge encimske sisteme, po navadi povezane z uporabo zaviralcev ACE.
English: Elderly population No dose adjustment is necessary in elderly patients.
Slovenian: Starejša populacija Starejšim bolnikom odmerka ni treba prilagoditi.
English: High temperature (fever).
Slovenian: • Zvišana telesna temperatura (vročina).
English: Following an oral dose of 14C-labelled candesartan cilexetil, approximately 26% of the dose is excreted in the urine as candesartan and 7% as an inactive metabolite while approximately 56% of the dose is recovered in the faeces as candesartan and 10% as the inactive metabolite.
Slovenian: Po peroralnem odmerku s 14C-označenega cileksetilkandesartanata se približno 26 % odmerka izloči v urinu kot kandesartan in 7 % kot neaktivni presnovek, približno 56 % odmerka pa se pojavi v blatu kot kandesartan in 10 % kot neaktivni presnovek.
English: Do not take Atacand Plus if: you are allergic (hypersensitive) to candesartan cilexetil or hydrochlorothiazide or any of the other ingredients of Atacand Plus (see section 6).
Slovenian: Ne jemljite zdravila Atacand Plus: - če ste alergični (preobčutljivi) na cileksetilkandesartanat ali hidroklorotiazid ali na katerokoli sestavino zdravila Atacand Plus (glejte poglavje 6).
English: Hydrochlorothiazide is excreted in human milk in small amounts.
Slovenian: Hidroklorotiazid se pri človeku izloča v materinem mleku v majhni količini.
English: There is no indication of serious or exaggerated first dose hypotension or rebound effect after cessation of treatment.
Slovenian: Ni znakov, da bi se po prvem odmerku pojavila resna ali čezmerna hipotenzija, ali da bi se po prenehanju zdravljenja pojavil povratni učinek ("rebound").
English: It helps your body to get rid of water and salts like sodium in your urine.
Slovenian: Telesu pomaga z urinom izločiti vodo in soli, kot je natrij.
English: Calcium or Vitamin D supplements.
Slovenian: • Dodatke kalcija ali vitamina D.
English: Patients received candesartan or placebo with other antihypertensive treatment added as needed.
Slovenian: Bolniki so prejemali kandesartan ali placebo ter so jim dodali druge antihipertenzive, kot je bilo potrebno.
English: Very rare Renal impairment, including renal failure in susceptible patients (see section 4.4)
Slovenian: Bolezni sečil zelo redki okvara ledvic, vključno z odpovedjo ledvic pri občutljivih bolnikih (glejte poglavje 4.4)
English: Worsening of existing lupus erythaematosus-like reactions or appearance of unusual skin reactions.
Slovenian: • Poslabšanje obstoječih, eritematoznemu lupusu podobnih reakcij ali pojav nenavadnih kožnih reakcij.
English: During long-term therapy, reduced peripheral resistance contributes to the blood pressure reduction.
Slovenian: Med dolgotrajnim zdravljenjem zmanjšanje perifernega upora pripomore k znižanju krvnega tlaka.
English: If calcium supplements or Vitamin D must be prescribed, serum calcium levels should be monitored and the dose adjusted accordingly.
Slovenian: Če je treba predpisati dodatke kalcija ali vitamin D, je treba koncentracijo kalcija v serumu kontrolirati in odmerek ustrezno prilagoditi.
English: Angiotensin II is the primary vasoactive hormone of the renin-angiotensin-aldosterone system and plays a role in the pathophysiology of hypertension and other cardiovascular disorders.
Slovenian: Angiotenzin II je primarni vazoaktivni hormon sistema renin-angiotenzin-aldosteron in ima vlogo v patofiziologiji hipertenzije in drugih kardiovaskularnih bolezni.
English: Atacand Plus may cause increased sensitivity of the skin to sun.
Slovenian: Zdravilo Atacand Plus lahko poveča občutljivost kože za sonce.
English: Atacand Plus can affect the way some other medicines work and some medicines can have an effect on Atacand Plus.
Slovenian: Zdravilo Atacand Plus lahko vpliva na delovanje nekaterih drugih zdravil in nekatera druga zdravila lahko vplivajo na zdravilo Atacand Plus.
English: There were 26.7 events per 1000 patient-years in the candesartan group versus 30.0 events per 1000 patientyears in the control group (relative risk 0.89, 95% CI 0.75 to 1.06, p=0.19).
Slovenian: V skupini s kandesartanom so zabeležili 26,7 dogodka na 1000 bolnik-let, v kontrolni skupini pa 30,0 dogodkov na 1000 bolnik-let (relativno tveganje 0,89, 95 % IZ 0,75-1,06, p = 0,19).
English: Water tablets (diuretics).
Slovenian: • Tablete za odvajanje vode (diuretike).
English: At the doses contained in Atacand Plus, only minimal effects were observed.
Slovenian: Med uporabo odmerkov, ki jih vsebuje zdravilo Atacand Plus, so opažali le minimalne učinke.
English: Whilst there is no controlled epidemiological data on the risk with AIIRAs, similar risks may exist for this class of drugs.
Slovenian: O tveganju z ARAII ni kontroliranih epidemioloških podatkov, vendar lahko s to skupino zdravil obstajajo podobna tveganja.
English: A reduction in your red or white blood cells or platelets.
Slovenian: • Zmanjšanje števila rdečih ali belih krvnih celic ali trombocitov.
English: Withdrawals from treatment due to adverse events were similar with candesartan cilexetil/hydrochlorothiazide (2.3-3.3%) and placebo (2.7-4.3%).
Slovenian: Delež umikov zaradi neželenih učinkov je bil s cileksetilkandesartanatom/hidroklorotiazidom (2,3-3,3 %) in placebom (2,7-4,3 %) podoben.
English: Atacand Plus once daily provides effective and smooth blood pressure reduction over 24 hours, with little difference between maximum and trough effects during the dosing interval.
Slovenian: Zdravilo Atacand Plus enkrat na dan zagotavlja učinkovito in enakomerno 24-urno znižanje krvnega tlaka z majhno razliko med največjim in najmanjšim učinkom med odmernim intervalom.
English: However, the blood pressure response and the incidence of adverse events are similar after a given dose of Atacand Plus in young and elderly patients (see section 4.2).
Slovenian: Toda odziv krvnega tlaka in incidenca neželenih učinkov sta po določenem odmerku zdravila Atacand Plus pri mladih in starejših bolnikih podobna (glejte poglavje
English: If re-administration of treatment is essential, it is recommended to protect areas exposed to the sun or to artificial UVA radiation.
Slovenian: Če se izkaže, da je ponovna uporaba zdravila nujna, je priporočljivo zaščititi predele, izpostavljene soncu ali umetni svetlobi UVA.
English: Your doctor will normally advise you to stop taking Atacand Plus before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Atacand Plus.
Slovenian: Zdravnik vam bo praviloma svetoval, da nehajte jemati zdravilo Atacand Plus, preden zanosite ali čim ugotovite, da ste noseči, in vam bo namesto zdravila Atacand Plus predpisal neko drugo zdravilo.
English: An increased or reduced amount of potassium in your blood, especially if you already have kidney problems or heart failure.
Slovenian: Zvišanje ali znižanje kalija v krvi, zlasti če že imate težave z ledvicami ali srčno popuščanje.
English: you have persistently high levels of calcium in your blood.
Slovenian: - če imate trajno visok kalcij v krvi.
English: Back pain, pain in joints and muscles.
Slovenian: • Bolečine v hrbtu, bolečine v sklepih in mišicah.
English: you are vomiting, have recently had severe vomiting, or have diarrhoea.
Slovenian: - če bruhate, ste pred kratkim močno bruhali ali imate drisko.
English: The main manifestation of an overdose of hydrochlorothiazide is acute loss of fluid and electrolytes.
Slovenian: Glavni znak prevelikega odmerjanja hidroklorotiazida je akutna izguba tekočine in elektrolitov.
English: Since there is no effect on the degradation of kinins, or on the metabolism of other substances, such as substance P, AIIRAs are unlikely to be associated with cough.
Slovenian: Ker ARAII ne vplivajo na razgradnjo kininov ali na presnovo drugih snovi, npr. snovi P, ni verjetno, da bi jih spremljal kašelj.
English: It is not known to what extent hydrochlorothiazide is removed by haemodialysis.
Slovenian: Ni znano, v kolikšni meri hemodializa odstrani hidroklorotiazid.
English: The usual dose of Atacand Plus is one tablet once a day Swallow the tablet with a drink of water.
Slovenian: Običajen odmerek zdravila Atacand Plus je ena tableta enkrat na dan. Tableto zaužijte s kozarcem vode.
English: Like all medicines, Atacand Plus can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo Atacand Plus neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: you have heart, liver or kidney problems.
Slovenian: - če imate težave s srcem, jetri ali ledvicami.
English: WHAT ATACAND PLUS IS AND WHAT IT IS USED FOR
Slovenian: KAJ JE ZDRAVILO ATACAND PLUS IN ZA KAJ GA UPORABLJAMO
English: Total plasma clearance of candesartan is about 0.37 ml/min/kg, with a renal clearance of about 0.19 ml/min/kg.
Slovenian: Celotni plazemski očistek kandesartana je približno 0,37 ml/min/kg, njegov ledvični očistek pa je približno 0,19 ml/min/kg.
English: The addition of hydrochlorothiazide did not significantly affect the outcome of foetal development studies in rats, mice or rabbits (see section 4.6).
Slovenian: Dodatek hidroklorotiazida ni bistveno vplival na izid v študijah razvoja plodov pri podganah, miših ali kuncih (glejte poglavje
English: • Hydrochlorothiazide belongs to a group of medicines called diuretics (water tablets).
Slovenian: • Hidroklorotiazid spada v skupino zdravil, imenovanih diuretiki (tablete za odvajanje vode).
English: It is important to keep taking Atacand Plus every day.
Slovenian: Pomembno je, da zdravilo Atacand Plus vzamete vsak dan.
English: Postural hypotension may become aggravated by simultaneous intake of alcohol, barbiturates or anaesthetics.
Slovenian: Posturalno hipotenzijo lahko poslabša sočasno uživanje alkohola ali barbituratov ali uporaba anestetikov.
English: Hydrochlorothiazide may increase the risk of acute renal insufficiency especially with high doses of iodinated contrast media.
Slovenian: Hidroklorotiazid lahko poveča tveganje akutne insuficience ledvic, zlasti ob velikih odmerkih kontrastnih sredstev z jodom.
English: Angiotensin II Receptor Antagonists (AIIRAs):
Slovenian: Antagonisti receptorjev angiotenzina II (ARAII):
English: This medicinal product does not require any special temperature storage conditions.
Slovenian: • Za shranjevanje zdravila niso potrebna posebna navodila glede temperature.
English: Therefore, the use of Atacand Plus is not recommended until this condition has been corrected.
Slovenian: Zato zdravila Atacand Plus ni priporočljivo uporabiti, dokler se to stanje ne odpravi.
English: Based on in vitro data, no interaction would be expected to occur in vivo with medicinal products whose metabolism is dependent upon cytochrome P450 isoenzymes CYP1A2, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 or CYP3A4.
Slovenian: Glede na podatke in vitro ni pričakovati medsebojnega delovanja in vivo z zdravili, katerih presnova je odvisna od izoencimov CYP1A2, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 ali CYP3A4 citokroma P450.
English: The pharmacokinetics in patients undergoing haemodialysis were similar to those in patients with severe renal impairment.
Slovenian: Farmakokinetika pri bolnikih na hemodializi je bila podobna k bolnikih s hudo okvaro ledvic.