FrancophonIA/ELRC3.0 huggingface dataset:
English: This pack (treatment initiation pack) is used when you start your treatment with Lacosamide Accord.
Croatian: Ovo pakiranje (pakiranje za početak liječenja) se koristi kada započinjete Vaše liječenje Lakozamid Accordom.
English: What Lacosamide Accord is and what it is used for
Croatian: Što je Lakozamid Accord i za što se koristi
English: What Lacosamide Accord is and what it is used for What you need to know before you take Lacosamide Accord How to take Lacosamide Accord Possible side effects
Croatian: Što je Lakozamid Accord i za što se koristi Što morate znati prije nego počnete uzimati Lakozamid Accord Kako uzimati Lakozamid Accord Moguće nuspojave
English: Therefore, this medicinal product should be used with caution in patients allergic to peanut or soya.
Croatian: Stoga je ovaj lijek potrebno upotrebljavati s oprezom u bolesnika koji su alergični na kikiriki ili soju.
English: What you need to know before you take Lacosamide Accord
Croatian: Što morate znati prije nego počnete uzimati Lakozamid Accord
English: • if you are allergic to peanut or soya.
Croatian: • ako ste alergični na kikiriki ili soju
English: The packages are marked with ‘week 1 (2, 3 or 4)'.
Croatian: Pakiranja su označena s ʻ1.(2., 3. ili 4.) tjedan'.
English: Uncommon: may affect up to 1 in 100 children Feeling sleepy or lacking in energy (lethargy).
Croatian: Manje često: mogu se javiti u do 1 do 100 djece osjećaju se pospano ili im nedostaje energije (letargija).
English: They will help you decide if you should take Lacosamide Accord or not.
Croatian: Liječnik će Vam pomoći u donošenju odluke trebate li uzimati Lakozamid Accord ili ne.
English: This dose is called a maintenance dose and will depend on how you respond to Lacosamide Accord.
Croatian: Ta doza naziva se dozom održavanja i ovisit će o Vašem odgovoru na Lakozamid Accord.
English: Packs of 14, 56, 60 or 168 tablets
Croatian: Pakiranja od 14, 56, 60 ili 168 tableta
English: Lacosamide Accord treatment initiation pack contains 4 different packages (one for each tablet strength) with 14 tablets each, for the first 2 to 4 weeks of therapy depending on the patient´s response and tolerability.
Croatian: Lakozamid Accord pakiranje za početak liječenja sadrži 4 različita pakiranja (jedno za svaku jačinu tablete), svako s 14 tableta, za prva 2 do 4 tjedna terapije ovisno o odgovoru i podnošljivosti bolesnika.
English: In particular, tell your doctor or pharmacist if you are taking any of the following medicines that affect your heart - this is because Lacosamide Accord can also affect your heart:
Croatian: Posebice obavijestite svog liječnika ili ljekarnika ako uzimate bilo koji od sljedećih lijekova koji utječu na srce - to je zato što Lakozamid Accord također može utjecati na srce:
English: • you have thoughts of harming or killing yourself.
Croatian: • ako imate misli o samoozljeđivanju ili samoubojstvu.
English: Lacosamide Accord is used as a long term treatment.
Croatian: Lakozamid Accord se koristi za dugotrajno liječenje.
English: • Swallow the Lacosamide Accord tablet with a glass of water.
Croatian: • Progutajte tabletu Lakozamid Accorda uz čašu vode.
English: • Take Lacosamide Accord twice each day- once in the morning and once in the evening.
Croatian: • Lakozamid Accord se mora uzimati dvaput na dan svakog dana, jednom ujutro i jednom navečer.
English: How to store Lacosamide Accord Contents of the pack and other information
Croatian: Kako čuvati Lakozamid Accord Sadržaj pakiranja i druge informacije
English: Listed below are the normal recommended doses of Lacosamide Accord for different age groups and weights.
Croatian: U nastavku su navedene uobičajene preporučene doze Lakozamid Accorda za različite dobne skupine i tjelesne težine.
English: • medicines used to treat certain types of irregular heart beat or heart failure.
Croatian: • lijekovi koji se koriste u liječenju određenih vrsta nepravilnog srčanog ritma ili zatajenja srca.
English: Hypersensitivity to the active substance, soya lecithin or to any of the excipients listed in section 6.1.
Croatian: Preosjetljivost na djelatnu tvar, sojin lecitin ili neku od pomoćnih tvari navedenih u dijelu 6.1.
English: Not known: frequency cannot be estimated from available data Changes in behaviour, not acting like themselves.
Croatian: Nepoznato: ne može se procijeniti iz dostupnih podataka mijenja im se ponašanje, ne ponašaju se uobičajeno.
English: • It is used to treat a certain type of epilepsy characterised by the occurrence of partial-onset seizure with or without secondary generalisation.
Croatian: • Koristi se za liječenje određenog oblika epilepsije karakteriziranog pojavom parcijalnih napadaja sa sekundarnom generalizacijom ili bez nje.
English: • you have severe heart disease such as heart failure or have had a heart attack.
Croatian: • ako bolujete od teške srčane bolesti kao što je zatajenje srca ili ste imali srčani udar.
English: Table: Start of the treatment (the first 4 weeks)
Croatian: Tablica: Početak liječenja (prva 4 tjedna)
English: When you take Lacosamide Accord with other antiepileptic medicines Start of the treatment (the first 4 weeks)
Croatian: Kad uzimate Lakozamid Accord s drugim antepileptičkim lijekovima: Početak liječenja (prva 4 tjedna)
English: Outer carton - treatment initiation pack containing 4 cartons of 14 film-coated tablets
Croatian: Vanjska kutija - pakiranje za početak liječenja koje sadrži 4 kutije s 14 filmom obloženih tableta
English: • dizziness;
Croatian: • nesvjestica;
English: Seek advice immediately from your doctor if you get pregnant or are planning to become pregnant.
Croatian: Odmah zatražite savjet liječnika ako ste trudni ili ako planirate imati dijete.
English: The efficacy of lacosamide as adjunctive therapy at recommended doses (200 mg/day, 400 mg/day) was established in 3 multicenter, randomized, placebo-controlled clinical trials with a 12-week maintenance period.
Croatian: Djelotvornost lakozamida kao dodatne terapije u preporučenim dozama (200 mg/dan, 400 mg/dan) ustanovljena je u 3 multicentrična, randomizirana, placebom kontrolirana klinička ispitivanja u razdoblju održavanja od 12 tjedana.
English: Lacosamide Accord film-coated tablets are packed in PVC-PVDC/Aluminium blisters.
Croatian: Lakozamid Accord filmom obložene tablete zapakirane su u PVC-PVDC/aluminijske blistere.
English: Lacosamide Accord is available in packs of 14, 56, 60 or 168 film-coated tablets.
Croatian: Lakozamid Accord je dostupan u pakiranjima od 14, 56, 60 ili 168 filmom obloženih tableta.
English: For all antiepileptic medicinal products, it has been shown that in the offspring of treated women with epilepsy, the prevalence of malformations is two to three times greater than the rate of approximately 3 % in the general population.
Croatian: Za sve antiepileptičke lijekove pokazalo se da se u potomstva majki liječenih zbog epilepsije rizik od nastanka malformacija dvostruko ili trostruko povećava u usporedbi s očekivanom incidencijom u općoj populaciji od oko 3 %.
English: It is not recommended to take Lacosamide Accord if you are pregnant or breast-feeding, as the effects of lacosamide on pregnancy and the unborn baby or the new-born child are not known.
Croatian: Ne preporučuje se uzimanje Lakozamid Accorda ako ste trudni ili dojite jer nisu poznati učinci lakozamida na trudnoću i na plod ili novorođenče.
English: You will start your treatment with a low dose of Lacosamide Accord, usually 50 mg twice a day, and increase it week by week.
Croatian: Vaše liječenje ćete započeti niskom dozom Lakozamid Accorda, obično 50 mg dvaput na dan, i povećavati je iz tjedna u tjedan.
English: The efficacy and safety of lacosamide in conversion to monotherapy has been assessed in a historicalcontrolled, multicentre, double-blind, randomized trial.
Croatian: Djelotvornost i sigurnost lakozamida kod prijelaza na monoterapiju ocjenjivane su u povijesno kontroliranom, multicentričnom, dvostruko slijepom, randomiziranom ispitivanju.
English: • Lacosamide Accord is used in adults, adolescents and children aged 4 years and older.
Croatian: • Lakozamid Accord se koristi u odraslih, adolescenata i djece od navršenih 4 godine života.
English: In treated patients who completed titration and started withdrawing antiepileptic medicinal products ( 284 and 99 respectively), monotherapy was maintained in 71.5 % and 70.7 % of patients respectively for 57-105 days (median 71 days), over the targeted observation period of 70 days.
Croatian: Kod liječenih bolesnika koji su završili s titracijom i započeli s ukidanjem drugih antiepileptika (284, odnosno 99), monoterapija je održana u 71,5 % odnosno 70,7 % bolesnika kroz 57-105 dana (medijan 71 dan), preko ciljanog razdoblja promatranja od 70 dana.
English: Lacosamide Accord with alcohol As a safety precaution do not take Lacosamide Accord with alcohol.
Croatian: Kao sigurnosnu mjeru opreza ne uzimajte Lakozamid Accord s alkoholom.
English: Therefore dosage supplementation following haemodialysis is recommended (see section 4.2).
Croatian: Stoga se nakon hemodijalize preporučuje dodatna doza (vidjeti dio 4.2).
English: • You may take Lacosamide Accord with or without food.
Croatian: • Lakozamid Accord možete uzimati s hranom ili bez nje.
English: However, a higher incidence (≥5 % difference) of fall, diarrhoea and tremor has been reported in elderly patients compared to younger adult patients.
Croatian: Međutim, zabilježena je veća incidencija (≥ 5 % razlike) padova, proljeva i tremora u starijih bolesnika u odnosu na mlađe odrasle bolesnike.
English: The treatment initiation pack contains 4 cartons, each carton with 14 tablets of 50 mg, 100 mg, 150 mg and 200 mg.
Croatian: Pakiranje za početak liječenja sadrži 4 kutije, svaka kutija s 14 tableta od 50 mg, 100 mg, 150 mg i 200 mg.
English: Dosage in adolescents and children weighing 50 kg or more is the same as in adults (see above).
Croatian: Doziranje u adolescenata i djece tjelesne težine 50 kg ili više jednako je kao u odraslih (vidjeti gore).
English: Also tell your doctor or pharmacist if you are taking any of the following medicines - this is because they may increase or decrease the effect of Lacosamide Accord on your body:
Croatian: Obavijestite svog liječnika ili ljekarnika i ako uzimate bilo koji od sljedećih lijekova zato što oni mogu pojačati ili smanjiti učinak Lakozamid Accorda na Vaše tijelo:
English: Do not take Lacosamide Accord if you are allergic to lacosamide, or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na lakozamid ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: The patients were randomized to carbamazepine CR or lacosamide, provided as tablets, in a 1:1 ratio.
Croatian: Bolesnici su bili randomizirani na karbamazepin CR ili lakozamid, u obliku tableta, u omjeru 1:1.
English: Partial-onset seizures have a similar clinical expression in children from 4 years of age and in adults.
Croatian: Parcijalni napadaji imaju sličnu kliničku sliku u djece od navršene 4 godinih života i u odraslih.
English: 14 film-coated tablets 56 film-coated tablets 60 film-coated tablets 168 film-coated tablets 14 x 1 film-coated tablet 56 x 1 film-coated tablet
Croatian: 14 filmom obloženih tableta 56 filmom obloženih tableta 60 filmom obloženih tableta 168 filmom obloženih tableta 14 x 1 filmom obložena tableta 56 x 1 filmom obložena tableta
English: In adjunctive clinical trials in epilepsy patients, the incidence rate of reported first-degree AV Block is uncommon, 0.7 %, 0 %, 0.5 % and 0 % for lacosamide 200 mg, 400 mg, 600 mg or placebo, respectively.
Croatian: U dodatnim kliničkim istraživanjima u bolesnika s epilepsijom stopa incidencije prijavljenih AVblokova prvog stupnja manje je česta te iznosi 0,7%, 0%, 0,5% za lakozamid u dozi od 200 mg, 400 mg, 600 mg odnosno 0% za placebo.
English: Your doctor may also prescribe a starting dose of 100 mg of Lacosamide Accord twice a day.
Croatian: Vaš liječnik također može propisati početnu dozu od 100 mg Lakozamid Accorda dvaput na dan.
English: Eligible patients on a stable dose regimen of 1 to ≤ 3 antiepileptic medicinal products, who still experienced at least 2 partial-onset seizures during the 4 weeks prior to screening with seizure-free phase no longer than 21 days in the 8-week period prior to entry into the baseline period, were randomised to receive either placebo (n=172) or lacosamide (n=171).
Croatian: Podobni bolesnici na režimu stabilne doze od 1 do ≤ 3 antiepileptička lijeka koji su još uvijek iskusili najmanje 2 parcijalna napadaja tijekom 4 tjedna prije probira s razdobljima bez napadaja ne dulje od 21 dan u razdoblju od 8 tjedana prije ulaska u početno razdoblje, randomizirani su za primanje ili placeba (n=172) ili lakozamida (n=171).
English: Troubles with your memory, thinking or finding words, confusion;
Croatian: • problemi s pamćenjem, poteškoće u razmišljanju ili odabiru riječi, smetenost;
English: If you stop taking Lacosamide Accord
Croatian: Ako prestanete uzimati Lakozamid Accord
English: If you forget to take Lacosamide Accord
Croatian: Ako ste zaboravili uzeti Lakozamid Accord
English: In children weighing from 20 to under 30 kg, a maximum dose of 10 mg/kg/day is recommended and in children weighing from 30 to under 50 kg, a maximum dose of 8 mg/kg/day is recommended, although in open-label studies (see sections 4.8 and 5.2), a dose up to 12 mg/kg/day has been used by a small number of these children.
Croatian: U djece tjelesne težine od 20 do manje od 30 kg preporučena je maksimalna doza od 10 mg/kg/dan, a u djece tjelesne težine od 30 do manje od 50 kg preporučena je maksimalna doza od 8 mg/kg/dan, iako je u otvorenim ispitivanjima (vidjeti dijelove 4.8 i 5.2) doza do 12 mg/kg/dan primijenjena na malom broju te djece.
English: 50 mg: Each film-coated tablet contains 0.105 mg of lecithin (soya) 100 mg: Each film-coated tablet contains 0.210 mg of lecithin (soya) 150 mg: Each film-coated tablet contains 0.315 mg of lecithin (soya) 200 mg: Each film-coated tablet contains 0.420 mg of lecithin (soya) For the full list of excipients, see section 6.1.
Croatian: 50 mg: jedna filmom obložena tableta sadrži 0,105 mg lecitina (soje) 100 mg: jedna filmom obložena tableta sadrži 0,210 mg lecitina (soje) 150 mg: jedna filmom obložena tableta sadrži 0,315 mg lecitina (soje) 200 mg: jedna filmom obložena tableta sadrži 0,420 mg lecitina (soje) Za cjeloviti popis pomoćnih tvari vidjeti dio 6.1.
English: Lacosamide Accord may make you dizzy -this could increase the risk of accidental injury or a fall.
Croatian: Lakozamid Accord može kod Vas izazvati omaglicu - to može povećati rizik od slučajne ozljede ili pada.
English: • a medicine for HIV called ritonavir;
Croatian: • lijek za HIV zvan ritonavir;
English: The decrease in non-renal clearance in the patients of the study was estimated to give a 20 % increase in the AUC of lacosamide.
Croatian: Procijenjeno je da smanjenje nebubrežnog klirensa u bolesnika u ispitivanju povećava AUC lakozamida za 20 %.
English: Lacosamide treatment may also be initiated with a single loading dose of 200 mg, followed approximately 12 hours later by a 100 mg twice a day (200 mg/day) maintenance dose regimen.
Croatian: Liječenje lakozamidom može se također započeti pojedinačnom udarnom dozom od 200 mg, nakon čega otprilike nakon 12 sati slijedi režim doze održavanja od 100 mg dvaput na dan (200 mg/dan).
English: • medicines for fungal infections called fluconazole, itraconazole or ketoconazole;
Croatian: • lijekovi za liječenje gljivičnih infekcija zvani flukonazol, itrakonazol ili ketokonazol
English: A safety pharmacology study with intravenous administration of lacosamide in anesthetized dogs showed transient increases in PR interval and QRS complex duration and decreases in blood pressure most likely due to a cardiodepressant action.
Croatian: U ispitivanju sigurnosne farmakologije u kojem je lakozamid primijenjen intravenski anesteziranim psima primijećeno je prolazno produljenje PR-intervala i proširenje QRS-kompleksa te sniženje krvnog tlaka, najvjerojatnije zbog kardiodepresivnog učinka.
English: 100 mg/day or 200 mg/day
Croatian: 100 mg/dan ili 200 mg/dan
English: Talk to your doctor before taking Lacosamide Accord if:
Croatian: Obratite se svom liječniku prije nego uzmete Lakozamid Accord:
English: In these patients it should be considered to perform an ECG before a lacosamide dose increase above 400mg/day and after lacosamide is titrated to steady-state.
Croatian: U ovih bolesnika treba razmotriti snimanje EKG-a prije povećanja doze lakozamida iznad 400 mg/dan i nakon što je lakozamid titriran do stanja dinamičke ravnoteže.
English: • you have a heart problem that affects the beat of your heart and you often have a particulary slow, fast or irregular heart beat (such as AV block, atrial fibrillation and atrial flutter).
Croatian: • ako imate srčani problem koji utječe na srčani ritam i često imate osobito usporene, ubrzane ili nepravilne otkucaje srca (kao što su AV blok, treperenje pretklijetki i lepršanje pretklijetki).
English: The discontinuation rate due to adverse events observed with lacosamide was 21.0 % (13/62) in elderly patients versus 9.2 % (35/382) in younger adult patients.
Croatian: Stopa prekida liječenja zbog nuspojava zabilježenih s lakozamidom bila je 21,0% (13/62) u starijih bolesnika naspram 9,2% (35/382) u mlađih odraslih bolesnika.
English: Do not drive, cycle or use any tools or machines until you know how this medicine affects you.
Croatian: Nemojte voziti automobil ili bicikl, niti koristiti alate ili strojeve dok ne znate kako ovaj lijek utječe na Vas jer Lakozamid Accord može uzrokovati omaglicu ili zamućen vid.
English: Blood tests may show abnormal liver function , liver injury;
Croatian: • krvne pretrage mogu ukazivati na promijenjenu funkciju jetre, oštećenje jetre;
English: Overall the proportion of subjects with a 50% reduction in seizure frequency was 23 %, 34 %, and 40 % for placebo, lacosamide 200 mg/day and lacosamide 400 mg/day.
Croatian: Ukupni udio ispitanika s 50 % smanjenom frekvencijom parcijalnih napadaja bio je 23 % u skupini s placebom, 34 % u skupini s lakozamidom 200 mg/dan i 40 % u skupini s lakozamidom 400 mg/dan.
English: However, cases with second- and third- degree AV Block associated with lacosamide treatment have been reported in postmarketing experience.
Croatian: Međutim, slučajevi pojave AV-bloka drugog i trećeg stupnja povezani s liječenjem lakozamidom zabilježeni su tijekom razdoblja nakon stavljanja lijeka u promet.
English: Depending on response and tolerability, Lacosamide Accord 150 mg tablets may be taken twice a day during the third week and Lacosamide Accord 200 mg tablets twice a day during the fourth week.
Croatian: Ovisno o odgovoru i podnošljivosti, Lakozamid Accord tablete od 150 mg mogu se uzimati dvaput na dan tijekom trećeg tjedna i Lakozamid Accord tablete od 200 mg dvaput na dan tijekom četvrtog tjedna.
English: This medicinal product contains lecithin (soya).
Croatian: Ovaj lijek sadrži lecitin (soju).
English: Hypoesthesia Dysarthria Disturbance in attention Paraesthesia
Croatian: Hipoestezija Dizartrija Poremećaj pažnje Parestezija
English: Treatment initiation pack (in adolescent and children weighing 50 kg or more and adults only) Lacosamide Accord 50 mg film-coated tablets
Croatian: Pakiranje za početak liječenja (samo za adolescente i djecu tjelesne težine veće od 50 kg, te odrasle) Lakozamid Accord 50 mg filmom obložene tablete
English: • In this type of epilepsy, fits first affect only one side of your brain.
Croatian: • U tom obliku epilepsije napadaji prvo zahvaćaju samo jednu stranu mozga, ali se nakon toga mogu proširiti i na veća područja zahvaćajući pritom obje strane mozga.
English: Depending on response and tolerability, the maintenance dose can be further increased by 2 mg/kg/day every week.
Croatian: Ovisno o odgovoru i podnošljivosti, doza održavanja svakih tjedan dana može se dalje povećavati za 2 mg/kg/dan.
English: In all of these controlled studies, the discontinuation rate due to adverse reactions was 12.2 % for patients randomized to lacosamide and 1.6 % for patients randomized to placebo.
Croatian: U svim navedenim kontroliranim ispitivanjima, stopa prekidanja liječenja zbog nuspojava bila je 12,2 % kod bolesnika randomiziranih na lakozamid i 1,6 % kod bolesnika randomiziranih na placebo.
English: Fall Skin laceration Contusion (1) Adverse reactions reported in post marketing experience.
Croatian: Pad Laceracije kože Kontuzija (1) Nuspojave prijavljene u razdoblju nakon stavljanja lijeka u promet.
English: If you take more Lacosamide Accord than you should If you have taken more Lacosamide Accord than you should, contact your doctor immediately.
Croatian: Ako ste uzeli više Lakozamid Accorda nego što ste smjeli, odmah se obratite liječniku.
English: In anesthetized dogs and Cynomolgus monkeys, at intravenous doses of 15-60 mg/kg, slowing of atrial and ventricular conductivity, atrioventricular block and atrioventricular dissociation were seen.
Croatian: Nakon intravenskih doza od 15 do 60 mg/kg anesteziranim psima i makaki majmunima primijećeni su usporeno provođenje impulsa kroz atrij i ventrikul te atrioventrikularni blok i atrioventrikularna disocijacija.
English: This was reported with lacosamide in 4.8 % (3/62) in elderly patients versus 1.6 % (6/382) in younger adult patients.
Croatian: Kod primjene lakozamida on je prijavljen u 4,8% (3/62) starijih bolesnika naspram 1,6% (6/382) u mlađih odraslih bolesnika.
English: Blood tests may show increased levels of liver enzymes and a type of white blood cell (eosinophilia); A widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form causing skin peeling in more than 30 % of the body surface (toxic epidermal necrolysis);
Croatian: • jako rasprostranjen osip s mjehurima i ljuštenjem kože, posebice oko usta, nosa, očiju i genitalija (Stevens-Johnsonov sindrom) te teži oblik koji uzrokuje ljuštenje kože na više od 30 % površine tijela (toksična epidermalna nekroliza);
English: • If your doctor decides to stop your treatment with Lacosamide Accord , they will tell you how to decrease the dose step by step.
Croatian: • Ako liječnik odluči prekinuti Vaše liječenje Lakozamid Accordom, dat će Vam upute kako postupno smanjivati dozu.
English: Based on the analysis of pooled placebo-controlled clinical trials in adjunctive therapy in 1,308 patients with partial-onset seizures, a total of 61.9 % of patients randomized to lacosamide and 35.2 % of patients randomized to placebo reported at least 1 adverse reaction.
Croatian: Na temelju analize udruženih placebom kontroliranih kliničkih istraživanja u dodatnoj terapiji u 1308 bolesnika s parcijalnim napadajima, ukupno 61,9 % bolesnika koji su randomizirani na lakozamid i 35,2 % bolesnika koji su randomizirani na placebo prijavilo je barem jednu nuspojavu.
English: During the second week, the patient takes Lacosamide Accord 100 mg tablets twice a day.
Croatian: Tijekom drugog tjedna bolesnik uzima Lakozamid Accord tabletu 100 mg dvaput na dan.
English: • If you have missed a dose beyond the first 6 hours of the scheduled dose, do not take the missed tablet anymore.
Croatian: • Ako je od propuštene doze proteklo više od 6 sati, nemojte uzimati propuštenu tabletu.
English: In this study, 425 patients aged 16 to 70 years with uncontrolled partial-onset seizures taking stable doses of 1 or 2 marketed antiepileptic medicinal products were randomized to be converted to lacosamide monotherapy (either 400mg/day or 300mg/day in a 3:1 ratio).
Croatian: U tom je ispitivanju 425 bolesnika u dobi od 16 do 70 godina s nekontroliranim parcijalnim napadajima, koji su uzimali stabilne doze od 1 ili 2 antiepileptika dostupna na tržištu, randomizirano na prijelaz na monoterapiju lakozamidom (400 mg/dan ili 300 mg/dan u omjeru 3 : 1).
English: Convulsion.
Croatian: • konvulzije.
English: 14 film-coated tablets.
Croatian: OBLIK I SADRŽAJ 14 filmom obloženih tableta.
English: When you take Lacosamide Accord with other antiepileptic medicines The usual starting dose of Lacosamide Accord is 50 mg twice a day.
Croatian: Kad uzimate Lakozamid Accord s drugim antepileptičkim lijekovima Uobičajena je početna doza Lakozamid Accorda 50 mg dvaput na dan.