FrancophonIA/ELRC3.0 huggingface dataset:
English: In poultry enrofloxacin is poorly metabolized to its active metabolite ciprofloxacin (approximately 5 %).
Danish: Metaboliseringen til den aktive metabolit ciprofloxacin sker dårligt i fjerkræ (ca. 5 %).
English: Use of the product deviating from the instructions given by in the SPC may increase the prevalence of bacteria resistant to the fluoroquinolones and may decrease the effectiveness of treatment with other fluoroquinolones due to the potential for cross-resistance.
Danish: Hvis brugen af produktet afviger fra det som er beskrevet i produktresuméet kan det øge forekomsten af bakterier resistente overfor fluoroquinoloner og kan muligvis nedsætte effekten af behandling med andre fluoroquinoloner som følge af potentiel krydsresistens.
English: In studies where the dose could be calculated in mg/kg, although a dose of approximately 10 mg/kg bodyweight was effective as metaphylaxis it appeared that a higher dose was more effective for treatment of E. coli.
Danish: Undersøgelser, hvor dosis kunne beregnes i mg/kg, viste, at en højere dosis var mere effektiv til behandling af E. coli, selv om en dosis på 10 mg/kg legemsvægt var effektiv som metafylakse.
English: Doses up to 100 mg/kg bodyweight during 5 days or 30 mg/kg bodyweight for 3 weeks were clinically well tolerated in broilers.
Danish: Doser på op til 10 mg/kg legemsvægt i fem dage eller 30 mg/kg legemsvægt i tre uger var klinisk veltolereret i slagtekyllinger.
English: One ml of “Product name” (to be completed nationally) contains:
Danish: 1 ml ”Produkt navn” (færdiggøres nationalt) indeholder:
English: Baytril 10% oral solution at a dose rate of 100 ppm (approximately 10 mg/kg) for 6 days and repeating after a 3 day interval was shown to be safe to use in rabbits aged 30 days, in does at mating and 15 days after mating and when does were lactating.
Danish: Undersøgelsen viste, at en dosis på 100 ppm (ca. 10 mg/kg) Baytril 10 % oral opløsning i seks dage med tre dages mellemrum kunne indgives sikkert i 30 dage gamle kaniner, i hunkaniner ved parring og 15 dage efter parring, og når hunkaninerne ammede.
English: 4 days
Danish: 4 døgn
English: Do not use this veterinary medicinal product after the expiry date which is stated on the packaging.
Danish: Må ikke anvendes efter den udløbsdato, som er angivet på flasken efter EXP.
English: Animal Health Division Bayer House Strawberry Hill Newbury
Danish: Strawberry Hill Newbury
English: Chickens must not be slaughtered for human consumption until 3 days after the last treatment.
Danish: Kyllinger må tidligst slagtes til menneskeføde 3 dage efter behandling er afsluttet.
English: In chickens, the EU studies submitted are approximately 25 years old, involve experimental infections only and were conducted when the Minimum Inhibitory
Danish: For så vidt angår kyllinger, er de forelagte EU-undersøgelser ca. 25 år gamle, de involverer udelukkende eksperimentelle infektioner og blev udført på et tidspunkt, hvor mindste inhiberende koncentration (MIC) for E. coli var betydeligt lavere end MIC'en for E. coli i dag.
English: Do not use in the case of known hypersensitivity to the active substance, other (fluoro)quinolones or to any of the excipients.
Danish: Anvendes ikke i tilfælde af kendt overfølsomhed overfor den aktive substans, andre fluoroquinoloner eller et af hjælpestofferne.
English: Solution for use in drinking water.
Danish: Opløsning til anvendelse i drikkevand Klar gullig opløsning
English: Birds must not be slaughtered for human consumption during treatment.
Danish: Under behandling må fugle ikke slagtes til menneskeføde.
English: Netherlands Bayer B.V.
Danish: Bayer B.V.
English: Total number of rabbits x Average body weight in kg x 0.1 = Total volume (ml) per day
Danish: Total antal kaniner x gennemsnitlig legemsvægt i kg x 0,1 = total volumen (ml) pr dag
English: Treatment of the respiratory tract and of the digestive tract infections caused by the following bacteria susceptible to enrofloxacin:
Danish: Behandling af infektioner i luftvejene og fordøjelseskanalen forårsaget af følgende bakterier følsomme for enrofloxacin.
English: Hungary
Danish: Ungaren
English: 10 mg/kg bodyweight per day for 5 consecutive days.
Danish: 10 mg/kg legemsvægt dagligt i 5 på hinanden følgende dage.
English: CVMP Reflection paper on the use of fluoroquinolones in food- producing animals - Precautions for use in the SPC regarding prudent use guidance (EMEA/CVMP/416168/2006)http://www.ema.europa.eu/docs/en_GB/document_library/Other/2009/10/WC500005173.pdf
Danish: 6 CVMP Reflection paper on the use of fluoroquinolones in food- producing animals - Precautions for use in the SPC regarding prudent use guidance (EMEA/CVMP/416168/2006)http://www.ema.europa.eu/docs/en_GB/document_library/Other/2009/10/WC500005173.pdf anbefalede CVMP ændringen af de markedsføringstilladelser, for hvilke produktresumé, etikettering og indlægsseddel fremgår af bilag III for Baytril 10 % oral opløsning og relaterede navne (se bilag I).
English: From the data submitted however, it is not possible to determine the optimal dose rate for treatment of Escherichia coli in either chickens or turkeys.
Danish: Det er imidlertid ikke muligt at fastslå den optimale dosering til behandling af Escherichia coli i hverken kyllinger eller kalkuner ud fra de forelagte oplysninger.
English: The exposure of the environment from the use of the product in chickens (PECsoil 887 µg/kg) is greater than the exposure from the treatment of rabbits at the new proposed dose rate of 10 mg/kg during 5 days (PECsoil 361 µg/kg).
Danish: eksponeringen ved behandling af kaniner ved den nye foreslåede dosis på 10 mg/kg i fem dage (PECsoil 361 µg/kg).
English: Total number of birds x Average body weight in kg x 0.1 = Total volume (ml) per day
Danish: Totalt antal fugle x gennemsnitlig legemsvægt i kg x 0,1 = total volumen (ml) pr dag.
English: BAYER HEALTH CARE AG 51368 Leverkusen GERMANY
Danish: BAYER HEALTH CARE AG 51368 Leverkusen TYSKLAND
English: Calculate the daily quantity (ml) of “Product name” (to be completed nationally) required for treatment period as follows:
Danish: Formel til beregning af den daglige mængde (ml) ”Produkt navn” (færdiggøres nationalt):
English: The medicated water should be made up fresh each day just before it is offered to the animals.
Danish: Det medicinerede drikkevand skal opblandes lige inden administrationen til dyrene.
English: Turkeys must not be slaughtered for human consumption until 3 days after the last treatment
Danish: Kalkuner må tidligst slagtes til menneskeføde 3 dage efter behandling er afsluttet.
English: • Withdrawal period;
Danish: • tilbageholdelsesperiode
English: Rinse any splashes from skin or eyes immediately with water.
Danish: Spildes produktet på huden eller kommer i øjnene vaskes straks med vand.
English: Please read package leaflet carefully before use.
Danish: INDIKATION(ER) Læs indlægssedlen omhyggeligt før brug
English: In vitro susceptibility has been shown in strains of (i) Gram-negative species such as Escherichia coli, Pasteurella multocida and Avibacterium (Haemophilus) paragallinarum and (ii) Mycoplasma gallisepticum and Mycoplasma synoviae.
Danish: In vitro følsomhed er vist hos stammer af (i) Gram-negative bakterier som Escherichia coli, Pasteurella multocida og Avibacterium (Haemophilus) paragallinarum og (ii) Mycoplasma gallisepticum og Mycoplasma synoviae (se sektion 4.5)
English: Bayer Vital GmbH 51368 Leverkusen GERMANY
Danish: Bayer Vital GmbH 51368 Leverkusen TYSKLAND
English: Pharmacotherapeutic group: quinolone and quinoxaline antibacterials, fluoroquinolones.
Danish: Farmakoterapeutisk gruppe: antibakterielle quinoloner og quinoxaliner, flouroquinoloner ATCvet-kode: QJ01MA90
English: • Shelf life.
Danish: • holdbarhed.
English: Satisfactory data have been submitted to support the use of enrofloxacin at the proposed harmonised dose rate to treat Avibacterium paragallinarum, Pasteurella multocida, Mycoplasma gallisepticum and Mycoplasma synoviae in chickens; Mycoplasma gallisepticum, Mycoplasma synoviae and Pasteurella multocida in turkeys.
Danish: Der var blevet forelagt tilfredsstillende data til støtte for anvendelsen af enrofloxacin i den foreslåede harmoniserede dosering til behandling af Avibacterium paragallinarum, Pasteurella multocida, Mycoplasma gallisepticum og Mycoplasma synoviae i kyllinger og Mycoplasma gallisepticum, Mycoplasma synoviae og Pasteurella multocida i kalkuner.
English: Withdrawal periods
Danish: Tilbageholdelsesperioder
English: Rabbit: 15 days Do not administer to animals producing eggs for human consumption
Danish: Kanin: 15 døgn Må ikke anvendes til dyr, hvis æg er bestemt til
English: Chicken: 7 days Turkey: 10 days Do not administer to laying birds producing eggs for human consumption
Danish: Kyllinger: 7 døgn Kalkuner: 10 døgn Må ikke anvendes til fugle, hvis æg er bestemt til menneskeføde
English: Benefit-risk assessment
Danish: Benefit/risk-forholdet
English: Chickens: 3 days Not for use in laying hens
Danish: Kyllinger: 3 døgn Må ikke anvendes til æglæggende høner
English: The product has been shown to be efficacious in the treatment of E. coli, Avibacterium paragallinarum, Pasteurella multocida, Mycoplasma gallisepticum and Mycoplasma synoviae in chickens; E. coli, Mycoplasma gallisepticum, Mycoplasma synoviae and Pasteurella multocida in turkeys.
Danish: Det er påvist, at lægemidlet er effektivt til behandling af E. coli, Avibacterium paragallinarum, Pasteurella multocida, Mycoplasma gallisepticum og Mycoplasma synoviae i kyllinger og E. coli, Mycoplasma gallisepticum, Mycoplasma synoviae og Pasteurella multocida i kalkuner.
English: Chickens: 8 days Not for use in birds producing eggs for human consumption
Danish: Kyllinger: 8 døgn Må ikke anvendes til fugle, hvis æg er bestemt til menneskeføde
English: Shelf-life after first opening the immediate packaging: 12 weeks.
Danish: Holdbarhed efter første åbning af den indre emballage: 12 uger Dato for åbning bør skrives på etiketten.
English: ANNEX I
Danish: Bilag I
English: A warning in relation to the potential effects of overdosing of fluoroquinolones on cartilage during the growth phase is included in section 4.10 of the SPC (Overdose).
Danish: Punkt 4.10 (Overdosering) indeholder en advarsel vedrørende de potentielle virkninger af en overdosering af fluoroquinoloner på brusk i vækstfasen.
English: Grounds for amendment of the summary of product characteristics, labelling and package leaflet
Danish: Begrundelser for ændring af produktresumé, etikettering og indlægsseddel:
English: Enrofloxacin 100 mg/ml oral solution Poultry (specifically broiler chickens, broiler breeders and pullets being reared as layers) and turkeys
Danish: Oral opløsning Fjerkræ (specifikt slagtekyllinger, avlsdyr og ungdyr opdrættet til æglægning) og kalkuner
English: Chicken and turkey: 3 days
Danish: Kylling og kalkun: 3 døgn
English: Any medicated water remaining after 24 hours after preparation must be discarded.
Danish: Efter 24 timer skal rester af vand indeholdende medicin kasseres Dato for åbning bør skrives på etiketten.
English: Shelf life after dilution or reconstitution according to directions: 24 hours.
Danish: Efter første åbning af den indre emballage: 12 uger Efter fortynding eller rekonstituering ifølge anvisning: 24 timer
English: At doses ≥ 50 mg/kg bodyweight/day administered for 5 days there was histological evidence of a detrimental effect on articular cartilage in broilers, but leg lesions were only clinically apparent in chickens and turkeys at doses > 100 mg/kg administered for ≥ 5 days.
Danish: Ved doser ≥ 50 mg/kg legemsvægt i fem dage var der histologiske tegn på en skadelig indvirkning på artikulær brusk i slagtekyllinger,
English: Available online at www.efsa.europa.eu/efsajournal de Jong A, Stephan B, Silley P.(2012).Fluoroquinolone resistance in E coli and Salmonella from healthy livestock and poultry in the EU.
Danish: Fluoroquinolone resistance in E coli and Salmonella from healthy livestock and poultry in the EU.
English: Lot: {number}
Danish: Batch {nummer}
English: Enrofloxacin 100 mg/ml oral solution Poultry
Danish: Enrofloxacin 100 mg/ml
English: The use of fluoroquinolones during the growth phase combined with a marked and prolonged increase in the intake of drinking water, and hence active ingredient, possibly due to high temperatures, may potentially be associated with damage of the articular cartilage.
Danish: Dette kan ses i tilfælde med markant og vedvarende stigning i indtagelse af drikkevand, og dermed aktivt stof, f.eks. som følge af høje temperaturer i omgivelserne.
English: Do not administer to layer replacement birds within 14 days of coming into lay.
Danish: Må ikke anvendes indenfor 14 dage forud for æglægningsperiodens begyndelse.
English: Replication forks and translational complexes cannot proceed beyond such enzyme-DNA-fluoroquinolone complexes, and inhibition of DNA and mRNA synthesis triggers events resulting in a rapid, drug concentration-dependent killing of pathogenic bacteria.
Danish: Den således inducerede inhibering af DNA- og mRNAsyntesen resulterer i hurtig, koncentrationsafhængig død af patogene bakterier.
English: Withdrawal period: Chickens: Meat and offal: 3 days.
Danish: Tilbageholdelsestid: Kyllinger: Slagtning: 3 døgn
English: Two enzymes essential in DNA replication and transcription, DNA gyrase and topoisomerase IV, have been identified as the molecular targets of fluoroquinolones.
Danish: Det er vist at de molekylære angrebspunkter for fluoroquinoloner er DNA-gyrase og topoisomerase IV, to essentielle enzymer i DNA-replikation og transkription.
English: Oplossing voor kippen kalkoenen
Danish: Oral opløsning Kyllinger og kalkuner
English: Chickens: 3 days Turkeys: 4 days
Danish: Kyllinger: 3 døgn Kalkuner: 4 døgn
English: Baytril 10% Enrofloxacin 100 mg/ml oral solution Chickens and turkeys
Danish: Baytril 10% Enrofloxacin 100 mg/ml
English: Cyprus
Danish: Cyperen
English: Turkeys: 3 days Not for use in laying turkey hens
Danish: Kalkuner: 3 døgn Må ikke anvendes til æglæggende kalkunhøner
English: Not for use in laying birds whose eggs are intended for human consumption
Danish: Må ikke anvendes til æglæggende fugle, hvis æg er bestemt til menneskeføde.
English: <Date of last renewal:> <{DD/MM/YYYY}><{DD month YYYY}>.
Danish: {måneder/år} eller <måneder/år>
English: Chickens: 3 days Turkeys: 3 days
Danish: Kyllinger: 3 døgn Kalkuner: 3 døgn
English: Rabbits: Meat and offal: 15 days.
Danish: Kalkuner: Slagtning: 3 døgn Kaniner: Slagtning: 15 døgn
English: {Name and address} <{tel}> <{fax}> <{e-mail}>
Danish: <{dage/måneder/år}> <{dage/måneder/år}>…
English: Use of fluoroquinolones during the growth phase combined with a marked and prolonged increase in the intake of drinking water, and hence active ingredient, possibly due to high temperatures, may potentially be associated with damage of the articular cartilage.
Danish: Brug af fluoroquinoloner under vækstfasen kan potentielt være forbundet med en beskadigelse af den artikulære brusk.
English: Enrofloxacin 100 mg/ml oral solution Poultry, non egglayers
Danish: Oral opløsning Fjerkræ, ikke æglæggende
English: Enrofloxacin 100 mg/ml oral solution Chickens (excluding laying hens), turkeys and rabbits
Danish: Oral opløsning Kyllinger (bort set fra æglæggende høner), kalkuner og kaniner
English: Shelf life of the veterinary medicinal product as packaged for sale: 4 years.
Danish: I salgspakning: 4 år
English: Not to be used in chicken producing eggs intended for human consumption
Danish: Må ikke anvendes til fjerkræ, hvis æg er bestemt til menneskeføde
English: PACKAGE LEAFLET FOR: “Product name” To be completed nationally.
Danish: ”Produkt navn” færdiggøres nationalt
English: • Target species;
Danish: • dyrearter, som lægemidlet er beregnet til
English: Target animal safety
Danish: Sikkerheden for det dyr, som lægemidlet er beregnet til
English: Do not administer to animals producing eggs for human consumption
Danish: Må ikke anvendes til dyr, hvis æg er bestemt til menneskeføde
English: Animal species Withdrawal periods
Danish: Tilbageholdelsestid menneskeføde
English: Active substance:
Danish: ud fra følgende betragtninger:
English: Not to be used in hens producing eggs for human consumption
Danish: Må ikke anvendes til høner, hvis æg er bestemt til menneskeføde
English: Bayer Animal Health GmBH
Danish: Storbritannien Bayer plc Animal Health Division Bayer House
English: • Posology;
Danish: • dosering
English: Date of first authorisation 19 May 2006 Date of latest renewal 23 June 2011
Danish: Dato for første markedsføringstilladelse 19. maj 2006 Dato for seneste fornyelse 23. juni 2011
English: You can usually carry on taking the drops, unless the effects are serious.
Danish: Man kan som regel fortsætte med at bruge dråberne, medmindre virkningerne er alvorlige.
English: Frequency cannot be estimated from available data
Danish: Hyppigheden kan ikke estimeres ud fra forhåndenværende data
English: This is enough for 4 weeks' usage.
Danish: Mængden rækker til 4 ugers brug.
English: The plasma protein binding of bimatoprost is approximately 88%.
Danish: Plasmaproteinbindingen af bimatoprost er ca. 88 %.
English: In all four cases, positive de-challenge and re-challenge were reported.
Danish: I alle fire tilfælde blev der rapporteret positiv dechallenge og rechallenge.
English: The response of these patients should be closely observed.
Danish: Disse patienters respons skal observeres nøje.
English: Neither nevi nor freckles of the iris appear to be affected by treatment.
Danish: Hverken naevi eller fregner i iris synes at blive påvirket af behandlingen.
English: Characteristics in older people
Danish: Egenskaber hos ældre mennesker
English: Chemical and physical in-use stability has been demonstrated for 28 days at 25°C.
Danish: Kemisk og fysisk holdbarhed efter anbrud er påvist i 28 dage ved 25 ºC.
English: The long term effects of increased iridial pigmentation are not known.
Danish: Langtidsvirkningerne af den øgede irispigmentering kendes ikke.
English: Put your next dose in at the usual time.
Danish: Dryp med næste dosis på det sædvanlige tidspunkt.
English: The ocular and systemic safety profile of the individual components is well established.
Danish: De enkelte komponenters okulære og systemiske sikkerhedsprofil er veldokumenteret.
English: The half-life of timolol in plasma is about 4 to 6 hours.
Danish: Timolols plasmahalveringstid er ca. 4-6 timer.
English: This may result in a decrease in systemic side effects and an increase in local activity.
Danish: Dette kan mindske de systemiske bivirkninger og øge den lokale effekt.
English: Hallucination:
Danish: Hallucinationer:
English: Tilt your head back and look at the ceiling.
Danish: Læg nakken tilbage og kig op i loftet.
English: In fact, the upper limit of the 95% CI did not exceed 0.14 mm Hg at week 12.
Danish: Faktisk oversteg den øvre grænse af 95 %konfidensintervallet ikke 0,14 mmHg ved uge 12.
English: Wash your hands before use.
Danish: Vask hænder før brug.
English: If one dose is missed, treatment should continue with the next dose as planned.
Danish: Hvis en dosis springes over, skal behandlingen fortsættes med den næste planlagte dosis.
English: Side effects where the frequency is not known
Danish: Bivirkninger, hvis hyppighed ikke er kendt
English: Before you use this medicine, tell your doctor if you have now or have had in the past
Danish: Før De bruger dette lægemiddel, skal De fortælle Deres læge, hvis De har eller tidligere har haft
English: It is acknowledged that in more than half of cases timolol eye drops were the only suspect drug, although additional risk factors such as elderly age, underlying disease or concomitant drugs may have contributed.
Danish: Det anerkendes, at timolol-øjendråber i mere end halvdelen af tilfælde var det eneste mistænkte lægemiddel, selvom yderligere risikofaktorer såsom høj alder, underliggende sygdom eller samtidige lægemidler kan have bidraget.
English: Timolol is not extensively bound to plasma.
Danish: Timolol bindes ikke i væsentlig grad til plasma.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Danish: Hvis De er gravid eller ammer, har mistanke om, at De er gravid, eller planlægger at blive gravid, skal De spørge deres læge eller apotekspersonalet til råds, før De bruger dette lægemiddel.
English: If overdose occurs treatment should be symptomatic and supportive.
Danish: I tilfælde af overdosering gives symptomatisk og understøttende behandling.
English: From a microbiological point of view, the in-use storage times and conditions are the responsibility of the user and would normally not be longer than 28 days at 25°C.
Danish: Ud fra et mikrobiologisk synspunkt er brugeren ansvarlig for opbevaringstid og -betingelser efter anbrud, som normalt ikke bør overstige 28 timer ved 25 ºC.
English: This risk may increase with elderly age, and the psychiatric medical history appears to be a risk factor rather than confounding for development of hallucinations following timolol containing eye drops administration
Danish: Denne risiko kan stige med høj alder, og den psykiatriske sygehistorie ser ud til at være en risikofaktor snarere end en konfunderende faktor for udvikling af hallucinationer efter administration af øjendråber, der indeholder timolol.
English: Do not drive or use machines until the symptoms have cleared.
Danish: Lad være med at arbejde med værktøj eller maskiner, før symptomerne er væk.
English: Not known bronchospasm (predominantly in patients with pre-existing bronchospastic disease) 2, asthma
Danish: Ikke kendt bronkospasme, (hovedsageligt hos patienter med eksisterende bronkospastisk lidelse) 2, astma
English: Superior sulcus deepening:
Danish: Fordybning af øvre sulcus:
English: Very common conjunctival hyperaemia.
Danish: Meget almindelig konjunktival hyperæmi.
English: Patients with cardiovascular diseases should be watched for signs of deterioration of these diseases and of adverse reactions.
Danish: Patienter med kardiovaskulære sygdomme bør monitoreres for tegn på forværring af disse sygdomme og for bivirkninger.
English: Timolol may get into your breast milk.
Danish: Timolol kan komme ud i Deres modermælk.
English: The frequency of possible adverse reactions listed below is defined using the following convention:
Danish: Hyppigheden af nedennævnte bivirkninger er defineret ved brug af følgende konvention:
English: Thus, it is important to apply GANFORT as instructed and avoid it running onto the cheek or other skin areas.
Danish: Det er derfor vigtigt at applicere GANFORT som anvist og undgå, at det løber ned på kinden eller andre hudområder.
English: In the publication: Nanda T, Rasool N, Callahan AB, Stamper RL, Odel JG. Ophthalmic Timolol Hallucinations: A Case Series and Review of the Literature.
Danish: Publikationen: Nanda T, Rasool N, Callahan AB, Stamper RL, Odel JG. Ophthalmic Timolol Hallucinations: A Case Series and Review of the Literature.
English: • Reduced sexual urge; sexual dysfunction
Danish: • Nedsat sexlyst, seksuel dysfunktion
English: When using nasolacrimal occlusion or closing the eyelids for 2 minutes, the systemic absorption is reduced.
Danish: Hvis tårevejene aflukkes, eller øjenlågene lukkes i 2 minutter, nedsættes den systemiske absorption.
English: Systemic absorption of the individual components was minimal and not affected by co-administration in a single formulation.
Danish: Systemisk absorption af de enkelte stoffer var meget lav og blev ikke påvirket af samtidig administration i en enkelt formulering.
English: Patients with corneal diseases should be treated with caution.
Danish: Patienter med hornhindesygdomme skal behandles med forsigtighed.
English: It is a synthetic prostamide, structurally related to prostaglandin F2α (PGF2α) that does not act through any known prostaglandin receptors.
Danish: Det er et syntetisk prostamid, som i strukturen ligner prostaglandin F2α (PGF2α), og som ikke virker gennem nogen kendte prostaglandinreceptorer.
English: The usual dose is one drop once a day, either in the morning or in the evening in each eye that needs treatment.
Danish: Den sædvanlige dosis er en dråbe én gang dagligt enten om morgenen eller om aftenen i hvert øje, der skal behandles.