FrancophonIA/ELRC3.0 huggingface dataset:
English: This delivery system will ensure that the correct amount of nitric oxide is delivered by diluting INOmax with an oxygen/air mixture immediately before giving it to you.
Slovenian: Ta sistem za dovajanje bo zagotovil, da se dovaja pravilna količina dušikovega oksida, tako da razredči zdravilo INOmax s kisikom/mešanico zraka takoj pred uporabo pri vas ali vašemu otroku.
English: INOmax should only be delivered according to a neonatologist's prescription.
Slovenian: Zdravilo INOmax se sme dovajati le, če ga predpiše neonatolog.
English: All equipment, including connectors, tubing, and circuits, used in the delivery of nitric oxide must be made of materials compatible with the gas.
Slovenian: Vsa oprema, ki jo uporabljate pri dovajanju dušikovega oksida, vključno s priključki, cevmi in napeljavo, mora biti izdelana iz materialov, združljivih s tem plinom.
English: If there is no change in oxygenation during administration of INOmax at 1 ppm, the FiO2 should be increased by 10 %, the INOmax is discontinued, and the neonates monitored closely for signs of hypoxaemia.
Slovenian: Če se med uporabo zdravila INOmax v odmerku 1 ppm oksigenacija ne spremeni, povečajte FiO2 za 10 %, prekinite uporabo zdravila INOmax in pri novorojenčku skrbno opazujte morebiten pojav znakov hipoksemije.
English: In patients undergoing heart surgery, an increase in pulmonary artery pressure due to pulmonary vasoconstriction is frequently seen.
Slovenian: Pri bolnikih, pri katerih opravljajo srčni kirurški poseg, so pogosto opazili povišanje tlaka v pljučni arteriji zaradi pljučne vazokonstrikcije.
English: Driving and using machines Not relevant.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Ni pomembno.
English: This is due to unwanted pulmonary vasodilation caused by inhaled nitric oxide, resulting in a further increase of already existing pulmonary hyperperfusion thus potentially giving raise to forward or backward failure.
Slovenian: Vzrok je neželena pljučna vazodilatacija, ki jo povzroča vdihnjeni dušikov oksid, kar lahko pripelje do nadaljnjega povečanja že obstoječe pljučne hiperperfuzije in posledično morda do miokardnega infarkta sprednje ali zadnje stene.
English: In addition, nitric oxide has affinity to metalloproteins and may also react with SH-groups in protein forming nitrosyl compounds.
Slovenian: Poleg tega ima dušikov oksid afiniteto do metaloproteinov in lahko reagira tudi s skupinami -SH v beljakovinah ter tvori nitrozilne spojine.
English: In clinical trials, no efficacy has been demonstrated with the use of inhaled nitric oxide in patients with congenital diaphragmatic hernia.
Slovenian: V kliničnih raziskavah niso dokazali učinkovitosti vdihovanja dušikovega oksida pri bolnikih s prirojeno diafragmalno hernijo.
English: It, therefore, is recommended that prior to the administration of nitric oxide, pulmonary artery catheterisation or echocardiographic examination of central haemodynamics be performed.
Slovenian: Zato je pred uporabo dušikovega oksida priporočljivo opraviti kateterizacijo pljučne arterije ali ehokardiografsko preiskavo osrednje hemodinamike.
English: newborn babies, babies, children, teenagers 0-17 years and adults with high blood pressure in the lungs, connected with heart surgery.
Slovenian: - novorojenčkov, otrok in mladostnikov, starih od 0 do 17 let, ter odraslih z visokim krvnim tlakom v pljučih, povezanim s srčnim kirurškim posegom.
English: Inhaled nitric oxide therapy should be maintained at 5 ppm until there is improvement in the neonate's oxygenation such that the FiO2 (fraction of inspired oxygen) < 0.60.
Slovenian: Zdravljenje z vdihavanjem dušikovega oksida obdržite na 5 ppm dokler se oksigenacija novorojenčka ne izboljša tako, da je FiO2 (delež vdihnjenega kisika) <0,60.
English: Significantly fewer neonates in the INOmax group required ECMO compared to the control group (31 % vs. 57 %, p<0.001).
Slovenian: ECMO potrebovalo značilno manjše število novorojenčkov kot v kontrolni skupini (31 % proti 57 %, p < 0,001).
English: The delivery system must provide a constant inhaled INOmax concentration irrespective of the ventilator.
Slovenian: Sistem za dovajanje mora zagotavljati stalno koncentracijo vdihanega zdravila INOmax, ne glede na respirator.
English: The pharmacokinetics of nitric oxide has been studied in adults.
Slovenian: Farmakokinetiko dušikovega oksida so raziskovali pri odraslih.
English: Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for > 70 % of the nitric oxide dose inhaled.
Slovenian: Kot prevladujoči presnovek dušikovega oksida, ki se izloča v urinu, so določili nitrat, ki ustreza >70 % odmerka vdihanega dušikovega oksida.
English: PHARMACEUTICAL FORM Inhalation gas.
Slovenian: FARMACEVTSKA OBLIKA plin za inhaliranje
English: Methaemoglobinaemia that does not resolve after reduction or discontinuation of therapy can be treated with intravenous vitamin C, intravenous methylene blue, or blood transfusion, based upon the clinical situation.
Slovenian: Methemoglobinemijo, ki je ne odpravi zmanjšanje odmerka ali prekinitev zdravljenja, lahko glede na klinično stanje zdravimo z intravenskim odmerjanjem vitamina C, intravenskim odmerjanjem metilen modrega ali s transfuzijo krvi.
English: When the decision is made to discontinue inhaled nitric oxide therapy, the dose should be reduced to 1 ppm for 30 minutes to one hour.
Slovenian: Ko ste se odločili prekiniti zdravljenje z vdihovanjem dušikovega oksida, za 30 minut do eno uro zmanjšajte odmerek na 1 ppm.
English: All regulations concerning handling of pressurised gas cylinders must be followed.
Slovenian: Upoštevati morate vse predpise o ravnanju s tlačnimi jeklenkami.
English: Nitric oxide is absorbed systemically after inhalation.
Slovenian: Dušikov oksid se po vdihavanju absorbira sistemsko.
English: In the event of a system failure or a wall-outlet power failure, a backup battery power supply and reserve nitric oxide delivery system should be available.
Slovenian: Zaradi morebitne okvare sistema ali prekinitve električnega toka morate imeti na voljo nadomestno napajanje z baterijo in nadomestni sistem za dovajanje dušikovega oksida.
English: INOmax appears to increase the partial pressure of arterial oxygen (PaO2) by dilating pulmonary vessels in better ventilated areas of the lung, redistributing pulmonary blood flow away from lung regions with low ventilation/perfusion (V/Q) ratios toward regions with normal ratios.
Slovenian: Videti je, da zdravilo INOmax povečuje parcialni tlak kisika v arterijah (PaO2) tako, da razširi pljučne žile v bolj ventiliranih delih pljuč in tako preusmeri krvni pretok iz predelov pljuč z nizkim razmerjem ventilacija/perfuzija proti predelom z normalnim razmerjem.
English: In adults undergoing heart surgery, methaemoglobin level should be measured within one hour of the initiation of INOmax therapy.
Slovenian: Pri odraslih, pri katerih se bo opravil srčni kirurški poseg, je treba eno uro po začetku zdravljenja z zdravilom INOmax izmeriti raven methemoglobina.
English: Inhaled nitric oxide has been shown to selectively reduce pulmonary vascular resistance and reduce the increased pulmonary artery pressure.
Slovenian: Pokazali so, da inhalacijski dušikov oksid selektivno zmanjša rezistenco pljučnih žil in zniža povišan tlak v pljučni arteriji.
English: If the fraction of methaemoglobin rises to a level that potentially compromises adequate oxygen delivery, the INOmax dose should be decreased and the administration of reducing medicinal products such as methylene blue may be considered.
Slovenian: Če se frakcija methemoglobina poviša na raven, ki lahko ogrozi zadostno dovajanje kisika, je treba odmerek zdravila INOmax zmanjšati ter razmisliti o uporabi zdravil za zniževanje methemoglobina, kot je metilen modro.
English: These effects in turn lead to improved blood circulation and oxygenation in the pulmonary circulation.
Slovenian: Ti učinki izboljšajo cirkulacijo krvi in oksigenacijo v pljučni cirkulaciji.
English: If the NO2 is > 0.5 ppm, the delivery system should be assessed for malfunction, the NO2 analyser should be recalibrated, and the INOmax and/or FiO2 should be reduced if possible.
Slovenian: >0,5 ppm, je treba oceniti motnje v delovanju sistema, ponovno umeriti analizator NO2 ter po možnosti znižati koncentracijo zdravila INOmax in/ali FiO2.
English: With a continuous flow neonatal ventilator, this may be achieved by infusing a low flow of INOmax into the inspiratory limb of the ventilator circuit.
Slovenian: Z respiratorjem za novorojenčke s stalnim pretokom lahko to dosežete tako, da low flow zdravila INOmax potopite v inspiracijsko vejo napeljave respiratorja.
English: For you or your child's safety, the delivery systems intended for administration of INOmax are fitted with devices that constantly measure the amount of nitric oxide, oxygen and nitrogen dioxide (a chemical formed when nitric oxide and oxygen are mixed) being delivered to the lungs.
Slovenian: Za vašo varnost in varnost vašega otroka je sistem za dovajanje zdravila INOmax opremljen z napravami, ki nenehno merijo količino dušikovega oksida, kisika in dušikovega dioksida (kemične snovi, ki se tvori ob mešanju dušikovega oksida in kisika), ki se dovaja v pljuča.
English: If oxygenation falls >20 %, INOmax therapy should be resumed at 5 ppm and discontinuation of INOmax therapy should be reconsidered after 12 to 24 hours.
Slovenian: >20 %, morate znova uvesti zdravljenje z zdravilom INOmax v odmerku 5 ppm, o možnosti prekinitve zdravljenja pa znova premislite po 12 do 24 urah.
English: This will be monitored by blood samples and if required the dose of inhaled nitric oxide must be reduced.
Slovenian: To bodo preverjali z vzorci krvi in, če bo to potrebno, bodo zmanjšali odmerek dušikovega oksida.
English: PHARMACEUTICAL FORM AND CONTENTS Inhalation gas
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA plin za inhaliranje
English: The efficacy of INOmax has been investigated in term and near-term newborns with hypoxic respiratory failure resulting from a variety of aetiologies.
Slovenian: Učinkovitost zdravila INOmax so raziskovali pri novorojenčkih s hipoksično respiratorno odpovedjo kot posledico različnih etiologij, ki so se rodili v roku ali blizu roka.
English: The inspired INOmax concentration must be measured continuously in the inspiratory limb of the circuit near the patient.
Slovenian: Koncentracijo vdihanega zdravila INOmax morate v inspiracijski veji napeljave ob bolniku nenehno meriti.
English: Gas cylinders are to be stored in wellventilated rooms or in ventilated sheds where they are protected from rain and direct sunlight.
Slovenian: Jeklenke shranjujte v dobro prezračenih prostorih ali v prezračenih lopah, kjer bodo zaščitene pred dežjem in neposredno sončno svetlobo.
English: How to use INOmax
Slovenian: Kako uporabljati zdravilo INOmax
English: All regulations concerning handling of pressure vessels must be followed.
Slovenian: Upoštevati morate vse predpise o ravnanju s tlačnimi posodami.
English: Prior to launch of the new indication of the product in each Member State, the Marketing Authorisation Holder shall agree the content and format of the educational material with the national competent authority.
Slovenian: Dodatni ukrepi za zmanjševanje tveganj Imetnik dovoljenja za promet z zdravilom naj pred uvedbo nove indikacije za zdravilo v vsaki državi članici s pristojnim nacionalnim organom dogovori vsebino in obliko izobraževalnega gradiva.
English: Nitrate is cleared from the plasma by the kidney at rates approaching the rate of glomerular filtration.
Slovenian: Ledvice očistijo nitrat iz plazme pri hitrosti, podobni hitrosti glomerulne filtracije.
English: OTHER SPECIAL WARNING(S), IF NECESSARY Ensure that the parent or guardian has read and is aware of the indications and cautions presented in the package leaflet prior to administration to their baby.
Slovenian: DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA Zagotovite, da pred uporabo zdravila pri otroku roditelj ali skrbnik prebere navodilo za uporabo in je seznanjen z indikacijami in opozorili v navodilu.
English: Acute toxicity is related to anoxia resulting from elevated methaemoglobin levels.
Slovenian: Akutna toksičnost je povezana z anoksijo, kar povzroča povišane ravni methemoglobina.
English: Nitric oxide is delivered to the patient via mechanical ventilation after dilution with an oxygen/air mixture using an approved (CE-marked) nitric oxide delivery system.
Slovenian: Dušikov oksid dovajamo bolnikom z mehanskim predihavanjem po razredčenju z mešanico kisika/zraka z uporabo odobrenega (z oznako CE) sistema za dovajanje dušikovega oksida.
English: LIST OF EXCIPIENTS Also contains nitrogen.
Slovenian: SEZNAM POMOŽNIH SNOVI Vsebuje tudi dušik.
English: Abrupt discontinuation of the administration of inhaled nitric oxide may cause rebound reaction; decrease in oxygenation and increase in central pressure and subsequent decrease in systemic blood pressure.
Slovenian: Nenadna prekinitev zdravljenja z vdihovanjem dušikovega oksida lahko povzroči povratno reakcijo, zmanjšanje oksigenacije, povečanje centralnega tlaka in posledično zmanjšanje sistemskega krvnega tlaka.
English: BRAILLE Justification for not including Braille accepted
Slovenian: PODATKI V BRAILLOVI PISAVI Sprejeta je utemeljitev, da Braillova pisava ni potrebna.
English: Persistent pulmonary hypertension of the newborn (PPHN) occurs as a primary developmental defect or as a condition secondary to other diseases such as meconium aspiration syndrome (MAS), pneumonia, sepsis, hyaline membrane disease, congenital diaphragmatic hernia (CDH), and pulmonary hypoplasia.
Slovenian: se pojavlja kot primarna razvojna okvara ali kot posledica drugih bolezni, kot so mekonijski aspiracijski sindrom (MAS), pljučnica, sepsa, sindrom dihalne stiske pri novorojenčkih, prirojena diafragmalna hernija (CDH - »congenital diaphragmatic hernia«) in pljučna hipoplazija.
English: Description of selected adverse reactions Inhaled nitric oxide therapy may cause an increase in methaemoglobin.
Slovenian: Opis izbranih neželenih učinkov Zdravljenje z vdihavanjem dušikovega oksida lahko povzroči povišanje ravni methemoglobina.
English: Inside this place, a separate premise should be dedicated to the storage of nitric oxide gas cylinders.
Slovenian: Znotraj tega prostora morate dodeliti ločene prostore, namenjene le shranjevanju jeklenk z dušikovim oksidom.
English: Effects on platelets
Slovenian: Učinek na krvne ploščice
English: It relaxes vascular smooth muscle by binding to the haeme moiety of cytosolic guanylate cyclase, activating guanylate cyclase and increasing intracellular levels of cyclic guanosine 3',5'-monophosphate, which then leads to vasodilation.
Slovenian: Pri tem aktivira gvanilat-ciklazo in poveča znotrajcelične koncentracije cikličnega gvanozin-3',5'-monofosfata, kar pripelje do vazodilatacije.
English: This gas mixture can improve heart function and increase the flow of blood through the lungs, which may help to increase the amount of oxygen that reaches the blood.
Slovenian: Ta mešanica plinov lahko izboljša delovanje srca in poveča pretok krvi v pljučih, kar lahko pripomore k povečanju količine kisika,
English: d
Slovenian: V
English: 4.4 Special warnings and precautions for use
Slovenian: 4.4 Posebna opozorila in previdnostni ukrepi Nezadosten odziv
English: Consideration should be given to discontinuation of treatment if no beneficial physiological effects are apparent after a 30-minute trial of therapy.
Slovenian: Če se po 30 minutah poskusnega zdravljenja ne pojavijo nobeni koristni fiziološki učinki, je treba razmisliti o prekinitvi zdravljenja.
English: Limay Porcheville 3 avenue Ozanne 78440 Porcheville France
Slovenian: Limay-Porcheville 3 avenue Ozanne 78440 Porcheville Francija
English: These include prilocaine (a local anaesthetic used for pain relief in association to minor painful procedures e.g. suturing, and minor surgical or diagnostic procedures) or glyceryl trinitrate (used to treat chest pain).
Slovenian: (lokalnim anestetikom, ki se uporablja za lajšanje bolečine pri manjših bolečih posegih, kot je šivanje, in manjših kirurških ali diagnostičnih postopkih) ali gliceriltrinitratom (za zdravljenje bolečin v prsih).
English: INOmax should be used and administered only by personnel specially trained in the use and handling of INOmax.
Slovenian: • Zdravilo INOmax sme uporabljati in dajati bolnikom samo osebje, ki je posebej usposobljeno za uporabo tega zdravila in ravnanje z njim.
English: Tested polymers which can be used in nitric oxide administration systems include polyethylene (PE) and polypropylene (PP).
Slovenian: Med preizkušene polimere, ki jih lahko uporabimo pri sistemih za dovajanje dušikovega oksida, spadata polietilen (PE)
English: INOmax cylinders should be stored secured in order to avoid falling and thus potentially causing harm.
Slovenian: • Jeklenke INOmax je treba shranjevati varno, tako da ne morejo pasti in povzročiti škode.
English: Prescription should be limited to those neonatal units that have received adequate training in the use of a nitric oxide delivery system.
Slovenian: Predpisovanje naj bo omejeno na tiste enote za novorojenčke, ki so ustrezno usposobljene za uporabo sistema za dovajanje dušikovega oksida.
English: In the presence of oxygen, nitric oxide is rapidly oxidised to derivatives which are toxic to the bronchial epithelium and alveolo-capillary membrane.
Slovenian: V prisotnosti kisika dušikov oksid hitro oksidira v snovi, ki so toksične za epitel bronhijev in alveolokapilarne membrane.
English: In one clinical study (NINOS), treatment groups were similar with respect to the incidence and severity of intracranial haemorrhage, Grade IV haemorrhage, periventricular leukomalacia, cerebral infarction, seizures requiring anticonvulsant therapy, pulmonary haemorrhage, or gastrointestinal haemorrhage.
Slovenian: V eni od kliničnih študij (NINOS) je bila pri skupinah bolnikov, ki so prejemali zdravilo, podobna incidenca in intenzivnost intrakranialnih krvavitev, krvavitev 4. stopnje, periventrikularne levkomalacije, možganske kapi, epileptičnih napadov, ki so zahtevali zdravljenje s protikonvulzivnimi zdravili, pljučnih krvavitev in krvavitev v prebavilih.
English: Data in adult humans are conflicting, and there has been no increase in bleeding complications in randomised controlled trials in term and near-term neonates with hypoxic respiratory failure.
Slovenian: Podatki pri odraslih ljudeh so si nasprotujoči, pri randomiziranih nadzorovanih kliničnih preizkušanjih na novorojenčkih s hipoksično respiratorno odpovedjo, rojenih v roku ali blizu roka, pa ni bilo povečanja zapletov pri krvavitvah.
English: Side effects that are commonly seen (affects more than 1 user in 100) in association with INOmax therapy include:
Slovenian: Neželeni učinki, ki se pogosto (pri več kot 1 od 100 bolnikov) pojavijo pri zdravljenju z zdravilom INOmax, so:
English: The gas cylinder should be put in an equipped site with appropriate material in order to hold the cylinder vertically.
Slovenian: Jeklenko morate namestiti v prostor, opremljen z ustreznimi materiali, ki omogočajo, da je jeklenka postavljena pokončno.
English: Bradycardia (low cardiac frequency) or too low amount of oxygen in the blood (oxygen desaturation/hypoxemia) due to sudden withdrawal of the treatment, Headache, dizziness, dry throat or shortness of breath following accidental ambient air exposure to nitric oxide (e.g. leakage from equipment or cylinder).
Slovenian: • bradikardija (zmanjšan srčni utrip) ali nezadostna količina kisika v krvi (desaturacija kisika/hipoksemija), ki nastane ob nenadni prekinitvi zdravljenja; • glavobol, omotica, suho grlo ali zasoplost po nenamerni izpostavljenosti dušikovemu oksidu v zraku okolja (npr. pri puščanju opreme ali jeklenke).
English: The starting dose of inhaled nitric oxide is 20 ppm (part per million) of inhaled gas.
Slovenian: Začetni odmerek inhalacijskega dušikovega oksida je 20 ppm (delcev na milijon) vdihanega plina.
English: The table below presents adverse reactions (ADRs) that have been reported with the use of INOmax from either the CINRGI trial of 212 neonates or post marketing experience in neonates (<1 months of age)).
Slovenian: V spodnji preglednici so neželeni učinki, o katerih so poročali pri uporabi zdravila INOmax v preskušanju CINRGI pri 212 novorojenčkih ali v obdobju trženja pri novorojenčkih (starih <1 mesec).
English: Prescription should be limited to those cardio-thoracic units that have received adequate training in the use of a nitric oxide delivery system.
Slovenian: Predpisovanje mora biti omejeno na kardiotorakalne enote, ki so ustrezno usposobljene za uporabo sistemov za dovajanje dušikovega oksida.
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER Linde Healthcare AB
Slovenian: IME IN NASLOV IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM Linde Healthcare AB
English: The monitoring of Methaemoglobin level
Slovenian: • Spremljanje ravni methemoglobina.
English: See section 4.2 for information on monitoring for NO2.
Slovenian: Informacije o nadzorovanju koncentracije NO2 boste našli v poglavju 4.2.
English: When inhaled, nitric oxide produces selective pulmonary vasodilation.
Slovenian: Dušikov oksid pri vdihavanju povzroča selektivno pljučno vazodilatacijo.
English: Pharmacotherapeutic group: Other respiratory system products, ATC code R07AX01.
Slovenian: Oznaka ATC: R07AX01.
English: In biological tissue, nitric oxide may form peroxynitrite with superoxide (O2-), an unstable compound which may cause tissue damage through further redox reactions.
Slovenian: Dušikov oksid v tkivih lahko s superoksidom (O2-) tvori peroksinitrit, nestabilno spojino, ki lahko z nadaljnjimi reakcijami oksidacije in redukcije povzroči poškodbe tkiv.
English: The physician should have access at the bedside to a reserve nitric oxide delivery system.
Slovenian: Zdravniki morajo ob bolniških posteljah imeti dostop do nadomestnega sistema za dovajanje dušikovega oksida.
English: Nitric oxide chemically reacts with oxygen to form nitrogen dioxide.
Slovenian: Dušikov oksid kemično reagira s kisikom in tvori dušikov dioksid.
English: Too rapid weaning from inhaled nitric oxide therapy carries the risk of a re-bound increase in pulmonary artery pressure with subsequent circulatory instability.
Slovenian: Prehitra prekinitev zdravljenja z inhalacijskim dušikovim oksidom pomeni tveganje za povratno povišanje tlaka v pljučni arteriji, kar posledično povzroči nestabilnost krvnega obtoka.
English: Store gas cylinders indoors in well-ventilated rooms or outdoors in ventilated sheds where they are protected from rain and direct sunlight.
Slovenian: Jeklenke shranjujte v zaprtih, dobro prezračenih prostorih ali na prostem, v prezračenih lopah, kjer bodo zaščitene pred dežjem in neposredno sončno svetlobo.
English: Animal models have shown that nitric oxide may interact with haemostasis, resulting in an increased bleeding time.
Slovenian: Poskusi na živalih so pokazali, da dušikov oksid lahko vpliva na hemostazo in podaljša krvavitve.
English: Your or your child's doctor will undertake monitoring of nitrogen dioxide and in case of elevated values the INOmax therapy will be adjusted, decreased accordingly.
Slovenian: Zdravnik, ki zdravi vas ali vašega otroka, bo spremljal ravni dušikovega dioksida in, če bodo te previsoke, ustrezno zmanjšal odmerek zdravila INOmax.
English: When inhaled, this gas mixture can improve the flow of blood through the lungs, which may help to increase the amount of oxygen that reaches your baby's blood.
Slovenian: Vdihavanje te mešanice plinov lahko izboljša pretok krvi skozi pljuča, kar pripomore k povečanju količine kisika, ki pride v dojenčkovo kri;
English: The potential risk of bleeding and haemostasis disorders The potential risks if used in combination with other vasodilators which act on cGMP or cAMP
Slovenian: • Možno tveganja, če se zdravilo uporablja v kombinaciji z drugimi vazodilatatorji, ki delujejo na cGMP ali cAMP.
English: What you need to know before you begin a treatment with INOmax
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo INOmax Ne uporabljajte zdravila INOmax:
English: The adverse events collected occurred at similar incidence rates in both groups.
Slovenian: Pogostnost neželenih učinkov je bila v obeh skupinah podobna.