FrancophonIA/ELRC3.0 huggingface dataset:
English: • If you are allergic to raltegravir or to any of the other ingredients in this medicine (listed in section 6).
Slovenian: Ne jemljite zdravila Isentress • če ste alergični na raltegravir ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Isentress is an antiviral medicine that works against the Human Immunodeficiency Virus (HIV).
Slovenian: Zdravilo Isentress je protivirusno zdravilo, ki deluje proti virusu humane imunske pomanjkljivosti (HIV), ki povzroča sindrom pridobljene imunske pomanjkljivosti (AIDS).
English: Two pack sizes are available: packs containing 1 bottle with 60 tablets, and multipacks comprising 3 bottles, each containing 60 tablets.
Slovenian: Na voljo sta dve velikosti pakiranja: pakiranje, ki vsebuje 1 plastenko s 60 tabletami in multi pakiranje s 3 plastenkami, v katerem vsaka vsebuje po 60 tablet.
English: 3 x 100 mg twice daily The weight-based dosing recommendation for the chewable tablet is based on approximately 6 mg/kg/dose twice daily (see section 5.2).
Slovenian: 3 x 100 mg dvakrat na dan Priporočilo za odmerjanje žvečljivih tablet glede na telesno maso temelji na približnem odmerku 6 mg/kg dvakrat na dan (glejte poglavje 5.2).
English: Patients had prior exposure to a median of 12 anti-retrovirals for a median of 10 years.
Slovenian: Bolniki so se predhodno zdravili z 12 protiretrovirusnimi zdravili (mediana vrednost), zdravljenje pa je trajalo 10 let (mediana vrednost).
English: Infections and infestations Uncommon genital herpes, folliculitis, gastroenteritis, herpes simplex, herpes virus infection, herpes zoster, influenza, lymph node abscess, molluscum contagiosum, nasopharyngitis, upper respiratory tract infection
Slovenian: Infekcijske in parazitske bolezni občasni genitalni herpes, folikulitis, gastroenteritis, herpes simpleks, okužba s herpes virusom, herpes zoster, gripa, absces bezgavk, molluscum contagiosum, nazofaringitis, okužba zgornjih dihalnih poti
English: What Isentress contains The active substance is raltegravir.
Slovenian: Kaj vsebuje zdravilo Isentress Učinkovina je raltegravir.
English: Dizziness has been reported in some patients during treatment with regimens containing raltegravir.
Slovenian: Pri nekaterih bolnikih, ki so se zdravili z režimom, ki je vseboval raltegravir, so poročali o pojavu omotice.
English: Treatment-naïve adult patients
Slovenian: Predhodno nezdravljeni odrasli bolniki
English: Raltegravir at concentrations of 31  20 nM resulted in 95 % inhibition (IC95) of HIV-1 replication (relative to an untreated virus-infected culture) in human T-lymphoid cell cultures infected with the cell-line adapted HIV-1 variant H9IIIB.
Slovenian: Na celičnih kulturah humanih T-limfoidnih celic, okuženih z za celično linijo prilagojeno varianto virusa HIV-1 H9IIIB, je raltegravir v koncentracijah 31  20 nM povzročil 95 % inhibicijo (IC95) replikacije virusa HIV-1 (v primerjavi z netretiranimi, z virusom okuženimi kulturami).
English: Administration of a high fat meal resulted in a 1.9% increase in AUC0-last, 28% decrease in Cmax, and 12% decrease in C24 hr.
Slovenian: Uporaba po obroku z veliko vsebnostjo maščob je povzročila povečanje AUC0-last za 1,9 %, zmanjšanje Cmax za 28 % in zmanjšanje C24ur za 12 %.
English: There were no clinically important pharmacokinetic differences due to gender, race, ethnicity or body weight in adults for raltegravir 400 mg twice daily, and no clinically meaningful effect on raltegravir pharmacokinetics was concluded.
Slovenian: Farmakokinetika se pri odraslih med uporabo 400 mg raltegravirja dvakrat na dan ni klinično pomembno razlikovala glede na spol, raso, etnično pripadnost ali telesno maso, tako da ni bilo ugotovljenega klinično pomembnega učinka raltegravirja na farmakokinetiko.
English: The chewable tablets are available in 25 mg and scored 100 mg strengths.
Slovenian: Žvečljive tablete so na voljo v jakostih 25 mg in 100 mg z razdelilno zarezo.
English: ISENTRESS chewable tablets contain fructose and sorbitol.
Slovenian: Zdravilo ISENTRESS žvečljive tablete vsebuje fruktozo in sorbitol.
English: In this study, administration of the chewable tablet with a high fat meal led to an average 6 % decrease in AUC, 62 % decrease in Cmax, and 188 % increase in C12hr compared to administration in the fasted state.
Slovenian: V tej študiji je jemanje žvečljivih tablet z obrokom z veliko maščobami vodilo do povprečno 6 % znižanja AUC, 62 % znižanja Cmax in 188 % zvišanja C12ur v primerjavi z jemanjem na tešče.
English: gastric pH altering agents: proton pump inhibitors (e.g. omeprazole), H2 blockers (e.g. famotidine, ranitidine, cimitedine)
Slovenian: učinkovine, ki spreminjajo pH v želodcu: zaviralci protonske črpalke (npr. omeprazol), antagonisti histaminskih receptorjev H2 (npr. famotidin, ranitidin, cimetidin)
English: • Do not use this medicine after the expiry date which is stated on the bottle after EXP.
Slovenian: • Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na plastenki poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
English: Strong inducers of drug metabolizing enzymes
Slovenian: Močni induktorji encimov, ki presnavljajo zdravila
English: • Keep the bottle tightly closed, with the desiccant in order to protect from moisture.
Slovenian: • Plastenko shranjujte tesno zaprto in s sušilom za zagotovitev zaščite pred vlago.
English: 2 white (1 mL) syringes
Slovenian: 2 beli (1-ml) brizgi
English: Comprehensive drug interaction studies were performed with raltegravir 400 mg twice daily and a limited number of drug interaction studies were performed for raltegravir 1,200 mg once daily.
Slovenian: Obsežne študije medsebojnega delovanja zdravil so bile izvedene s 400 mg raltegravirja dvakrat na dan, s 1.200 mg raltegravirja enkrat na dan pa je bilo izvedenih malo takšnih študij.
English: Isentress chewable tablets contain fructose and sorbitol If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this medicine.
Slovenian: Isentress žvečljive tablete vsebujejo fruktozo in sorbitol Če vam je zdravnik povedal, da ne prenašate nekaterih sladkorjev, se pred uporabo tega zdravila posvetujte z zdravnikom.
English: Each single-use sachet contains 100 mg of raltegravir which is to be suspended in 10 mL of water giving a final concentration of 10 mg per mL.
Slovenian: Eno vrečico za enkratno uporabo, ki vsebuje 100 mg raltegravirja, je treba suspendirati v 10 ml vode, da nastane suspenzija s končno koncentracijo 10 mg/ml.
English: Geometric Mean (%CV AUC (mg*hr/L)
Slovenian: Geometrična sredina (% KV AUC (mg*ur/l)
English: The active substance is raltegravir.
Slovenian: Učinkovina je raltegravir.
English: Scheduled appointments for the patient should be kept because the ISENTRESS dosage should be adjusted as the child grows.
Slovenian: Bolniki se morajo držati dogovorjenih obiskov, ker je treba odmerek zdravila ISENTRESS prilagajati tekom otrokove rasti.
English: Randomisation was stratified by screening HIV RNA level (≤ 50,000 copies/mL; and > 50,000 copies/mL) and by hepatitis B or C status (positive or negative).
Slovenian: Stratifikacija randomiziranih bolnikov je bila izvedena na osnovi vrednosti HIV RNA (≤ 50.000 kopij/ml in > 50.000 kopij/ml) in hepatitis B ali C statusa (pozitiven ali negativen).
English: Co-administration of raltegravir 1,200 mg once daily with aluminium/magnesium and calcium carbonate containing antacids are likely to result in clinically meaningful reductions in the plasma trough levels of raltegravir.
Slovenian: Sočasna uporaba 1.200 mg raltegravirja enkrat na dan z antacidi, ki vsebujejo aluminij/magnezij ali kalcijev karbonat, verjetno klinično pomembno zmanjša najmanjšo koncentracijo raltegravirja v plazmi.
English: At the highest dose levels, 400 mg/kg/day in females and 250 mg/kg/day in males, systemic exposure was similar to that at the clinical dose of 400 mg twice daily.
Slovenian: Pri največjih odmerkih, za mišje samice 400 mg/kg/dan in za mišje samce 250 mg/kg/dan, je bila sistemska izpostavitev podobna kot pri kliničnem odmerku 400 mg dvakrat na dan.
English: WHITE
Slovenian: BELA
English: Depression, including suicidal thoughts and behaviours, has been reported in some patients taking this medicine, particularly in patients with a prior history of depression or psychiatric illness.
Slovenian: Pri nekaterih bolnikih, ki so jemali to zdravilo, so poročali o depresiji, vključno s samomorilnimi mislimi in obnašanjem, še posebej pri bolnikih, ki so že kdaj prej imeli depresijo ali duševno bolezen.
English: It is not recommended to take Isentress with certain antacids (those containing aluminium and/or magnesium).
Slovenian: Jemanje zdravila Isentress z določenimi antacidi (tistimi, ki vsebujejo aluminij in/ali magnezij) ni priporočljivo.
English: The impact of other strong inducers of drug metabolizing enzymes, such as phenytoin and phenobarbital, on UGT1A1 is unknown; therefore, co-administration with raltegravir 1,200 mg once daily is not recommended.
Slovenian: Vpliv drugih močnih induktorjev encimov, ki presnavljajo zdravila, npr. fenitoina in fenobarbitala, na UGT1A1 ni znan, zato sočasna uporaba s 1.200 mg raltegravirja enkrat na dan ni priporočljiva.
English: Efavirenz 600 mg at bedtime (N = 282)
Slovenian: efavirenz 600 mg pred spanjem (n = 282)
English: ≥ 25 kg Chewable tablet
Slovenian: ≥ 25 kg žvečljiva tableta
English: Put the tip of the syringe into the cup of the prepared Isentress and pull back on the plunger.
Slovenian: Konico brizge potopite v posodico s pripravljenim zdravilom Isentress in izvlecite bat.
English: ISENTRESS granules for oral suspension contain fructose, sorbitol and sucrose.
Slovenian: Zdravilo ISENTRESS zrnca za peroralno suspenzijo vsebuje fruktozo, sorbitol in saharozo.
English: Co-administration of raltegravir 1,200 mg once daily and tipranavir/ritonavir is not recommended.
Slovenian: Sočasna uporaba 1.200 mg raltegravirja enkrat na dan in tipranavirja/ritonavirja ni priporočljiva.
English: Driving and using machines Do not operate machines, drive or cycle if you feel dizzy after taking this medicine.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Če ste med jemanjem tega zdravila omotični, ne smete upravljati s stroji, voziti ali kolesariti.
English: Step 13.
Slovenian: 13. korak Čiščenje
English: Use with caution in patients who have had myopathy or rhabdomyolysis in the past or have any predisposing issues including other medicinal products associated with these conditions (see section 4.4).
Slovenian: Pri bolnikih, ki so že kdaj imeli miopatijo ali rabdomiolizo, in pri bolnikih, ki imajo kateri koli predispozicijski dejavnik zanju, vključno z zdravljenjem z drugimi zdravili, ki so povezana z njima, je treba zdravilo uporabljati previdno (glejte poglavje 4.4).
English: Use with caution in patients who have had myopathy or rhabdomyolysis in the past or have any predisposing issues including other medicinal products associated with these conditions (see section 4.8).
Slovenian: Pri bolnikih, ki so že kdaj imeli miopatijo ali rabdomiolizo, in bolnikih, ki imajo kateri koli predispozicijski dejavnik, vključno z zdravljenjem z drugimi zdravili, ki so povezana z njima, je treba zdravilo uporabljati previdno (glejte poglavje 4.8).
English: To monitor maternal-foetal outcomes in patients inadvertently administered raltegravir while pregnant, an Anti-retroviral Pregnancy Registry has been established.
Slovenian: Register nosečnic, ki so se med nosečnostjo zdravile s protiretrovirusnimi zdravili Za spremljanje izidov nosečnosti (izidov za mater in plod) pri bolnicah, ki so med nosečnostjo nenamenoma jemale raltegravir, je bil vzpostavljen register nosečnic, ki so se med nosečnostjo zdravile s protiretrovirusnimi zdravili.
English: Pink, oval tablet, marked with "227" on one side.
Slovenian: Ovalna, rožnata, filmsko obložena tableta, z oznako "227" na eni strani.
English: Co-administration of raltegravir with antacids containing divalent metal cations may reduce raltegravir absorption by chelation, resulting in a decrease of raltegravir plasma levels.
Slovenian: Pri sočasni uporabi raltegravirja z antacidi, ki vsebujejo dvovalentne kovinske katione, se lahko zaradi kelacije zmanjša absorpcija raltegravirja, kar vodi do zmanjšane koncentracije raltegravirja v plazmi.
English: Elimination of raltegravir in vivo in human is primarily through the UGT1A1-mediated glucuronidation pathway.
Slovenian: Izločanje raltegravirja pri človeku in vivo poteka predvsem z glukuronidacijo z UGT1A1.
English: Uncommon mental disorder, suicide attempt, anxiety, confusional state, depressed mood, major depression, middle insomnia, mood altered, panic attack, sleep disorder, suicidal ideation, suicidal behaviour (particularly in patients with a pre-existing history of psychiatric illness)
Slovenian: Psihiatrične motnje pogosti nenormalne sanje, nespečnost, nočne more, nenormalno obnašanje, depresija občasni duševne motnje, poskus samomora, anksioznost, stanje zmedenosti, depresivno razpoloženje, huda oblika depresije, nespečnost srednje faze, sprememba razpoloženja, panični napad, motnje spanja, samomorilne misli, samomorilno vedenje (predvsem pri bolnikih, ki so v preteklosti že kdaj imeli psihiatrične motnje)
English: • 60 sachets of Isentress granules
Slovenian: • 60 vrečic zrnc zdravila Isentress
English: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) efavirenz (raltegravir 400 mg Single Dose)
Slovenian: Nenukleozidni zaviralci reverzne transkriptaze (NNRTI) efavirenz (raltegravir 400 mg enkratni odmerek)
English: • bloating; abdominal pain; diarrhoea; excessive gas in the stomach or bowel; feeling sick;
Slovenian: • napenjanje, bolečine v trebuhu, driska, preveč plina v želodcu ali črevesju, siljenje na bruhanje,
English: Severe and life-threatening skin reactions and allergic reactions have been reported in some patients taking this medicine.
Slovenian: Pri nekaterih bolnikih, ki jemljejo to zdravilo, so poročali o hudih in življenjsko nevarnih kožnih in alergijskih reakcijah.
English: 60 sachets, two 1 mL, two 3 mL and two 10 mL oral dosing syringes and 2 mixing cups.
Slovenian: 60 vrečic, dve 1-ml, dve 3-ml in dve 10-ml odmerni brizgi za peroralno dajanje in 2 posodici za mešanje
English: Administration of raltegravir following a high-fat meal increased AUC and Cmax by approximately 2-fold and increased C12 hr by 4.1-fold.
Slovenian: Pri jemanju raltegravirja po obroku z veliko vsebnostjo maščob sta bili vrednosti AUC in Cmax raltegravirja večji za približno 2-krat, vrednost C12 ur pa za 4,1-krat.
English: • infection of the hair roots; influenza; skin infection due to virus; vomiting or diarrhoea due to an infectious agent; upper respiratory tract infection; lymph node abscess
Slovenian: • okužba korenin las ali dlak, gripa, virusna okužba kože, bruhanje ali driska zaradi povzročitelja okužbe, okužba zgornjih dihalnih poti, gnojno vnetje bezgavk
English: At the highest dose levels, 400 mg/kg/day in females and 250 mg/kg/day in males, systemic exposure was similar to that at the clinical dose of 1,200 mg once daily.
Slovenian: Pri največjih odmerkih, za mišje samice 400 mg/kg/dan in za mišje samce 250 mg/kg/dan, je bila sistemska izpostavitev podobna kot pri kliničnem odmerku 1.200 mg enkrat na dan.
English: Adverse reactions considered by investigators to be causally related to raltegravir (alone or in combination with other ART), as well as adverse reactions established in post-marketing experience, are listed below by System Organ Class.
Slovenian: Spodaj so po organskih sistemih našteti neželeni učinki, ki so bili po oceni raziskovalcev vzročno povezani z raltegravirjem (samim ali v kombinaciji z drugimi protiretrovirusnimi zdravili), kot tudi neželeni učinki poročani v obdobju trženja zdravila.
English: Pull back the plunger.
Slovenian: Bat izvlecite nazaj ven.
English: Because the formulations have different pharmacokinetic profiles neither the granules for oral suspension nor the chewable tablets should be substituted for the 400 mg tablet or 600 mg tablet (see section 5.2).
Slovenian: Ker imajo farmacevtske oblike različne farmakokinetične profile, se niti zrnc za peroralno suspenzijo niti žvečljivih tablet ne sme zamenjati s 400 mg tabletami ali 600 mg tabletami (glejte poglavje 5.2).
English: Raltegravir AUC and Cmax increase dose proportionally over the dose range 100 mg to 1,600 mg. Raltegravir C12 hr increases dose proportionally over the dose range of 100 to 800 mg and increases slightly less than dose proportionally over the dose range 100 mg to 1,600 mg.
Slovenian: Pri odmerkih v razponu od 100 do 800 mg se vrednost C12 ur raltegravirja povečuje sorazmerno z odmerkom, pri odmerkih v razponu od 100 mg do 1.600 mg pa nekoliko manj kot sorazmerno z odmerkom.
English: Raltegravir 400 mg twice daily + OBT (N = 462)
Slovenian: raltegravir 400 mg dvakrat na dan + OBT (n = 462)
English: Because the formulations have different pharmacokinetic profiles neither the chewable tablets nor the granules for oral suspension should be substituted for the 400 mg tablet or 600 mg tablet (see section 5.2).
Slovenian: Ker imajo farmacevtske oblike različne farmakokinetične profile, se niti žvečljivih tablet niti zrnc za peroralno suspenzijo ne sme zamenjati s 400 mg tabletami ali 600 mg tabletami (glejte poglavje 5.2).
English: The safety profile observed in patients who used atazanavir and / or tenofovir disoproxil fumarate was generally similar to the safety profile of patients who did not use these agents.
Slovenian: Pri bolnikih, ki so se zdravili z atazanavirjem in/ali tenofovirdizoproksil fumaratom, je bil profil neželenih učinkov na splošno podoben kot pri bolnikih, ki se niso zdravili s tema zdraviloma, zato prilagajanje odmerka ni potrebno.
English: Therefore, no dose adjustment is required with use of proton pump inhibitors or H2 antagonists.
Slovenian: Pri uporabi zaviralcev protonske črpalke ali antagonistov histaminskih receptorjev H2 zato prilagajanje odmerka ni potrebno.
English: Get ready
Slovenian: 1. korak Pripravite se
English: Recommended Dose* for ISENTRESS Chewable Tablets for Paediatric Patients Weighing at Least 25 kg
Slovenian: Priporočeni odmerek* zdravila ISENTRESS žvečljive tablete za pediatrične bolnike s telesno maso najmanj 25 kg telesna masa (kg)
English: The impact of medicinal products that are strong inducers of UGT1A1 such as rifampicin on raltegravir 1,200 mg once daily is unknown, but co-administration is likely to decrease raltegravir trough levels based on the reduction in trough concentrations observed with raltegravir 400 mg twice daily; therefore, co-administration with raltegravir 1,200 mg once daily is not recommended.
Slovenian: Vpliv zdravil, ki so močni induktorji UGT1A1, kot je npr. rifampicin, na odmerek 1.200 mg raltegravirja enkrat na dan, ni znan, vendar je glede na zmanjšanje najmanjše koncentracije raltegravirja pri odmerku 400 mg dvakrat na dan verjetno, da sočasna uporaba zmanjša najmanjšo koncentracijo raltegravirja in zato sočasna uporaba s 1.200 mg raltegravirja enkrat na dan ni priporočljiva.
English: efavirenz (raltegravir 1,200 mg single dose)
Slovenian: efavirenz (raltegravir 1.200 mg enkratni odmerek)
English: Film-coating - Polyvinyl alcohol - Titanium dioxide - Polyethylene glycol 3350 - Talc - Red iron oxide - Black iron oxide
Slovenian: Filmska obloga - polivinilalkohol - titanov dioksid - polietilenglikol 3350 - smukec - rdeči železov oksid - črni železov oksid
English: One carton contains 60 sachets, two 1 mL, two 3 mL and two 10 mL oral dosing syringes and 2 mixing cups.
Slovenian: Ena škatla vsebuje 60 vrečic, dve 1-ml, dve 3-ml in dve 10-ml brizgi za peroralno dajanje in dve posodici za mešanje.
English: How should I store Isentress?
Slovenian: Kako naj shranjujem zdravilo Isentress?
English: In adults, there were no clinically important pharmacokinetic differences between patients with moderate hepatic insufficiency and healthy subjects.
Slovenian: Med odraslimi bolniki z zmerno jetrno insuficienco in zdravimi osebami ni bilo nobenih klinično pomembnih razlik v farmakokinetiki.
English: Co-administration of raltegravir (400 mg twice daily and 1,200 mg once daily) with aluminium and/or magnesium containing antacids is not recommended.
Slovenian: Sočasna uporaba raltegravirja (400 mg dvakrat na dan in 1.200 mg enkrat na dan) z antacidi, ki vsebujejo aluminij in/ali magnezij, ni priporočljiva.
English: atazanavir (raltegravir 1,200 mg single dose)
Slovenian: atazanavir (raltegravir 1.200 mg enkratni odmerek)
English: White to off-white, granular powder that may contain yellow or beige to tan particles, in a single-use sachet.
Slovenian: zrnca za peroralno suspenzijo bel do sivo bel zrnat prašek, ki lahko vsebuje rumene ali bež do rumeno rjave delce, v vrečici za enkratno uporabo
English: Number of chewable tablets
Slovenian: odmerek število žvečljivih tablet
English: However, if co-administration with rifampicin is unavoidable, a doubling of the dose of raltegravir can be considered in adults.
Slovenian: Če je sočasno zdravljenje z rifampicinom nujno potrebno, je treba pri odraslih razmisliti o podvojitvi odmerka raltegravirja.
English: ANTI-RETROVIRAL Protease inhibitors (PI) atazanavir /ritonavir (raltegravir 400 mg Twice Daily)
Slovenian: PROTIRETROVIRUSNA ZDRAVILA Zaviralci proteaz (PI) atazanavir/ritonavir (raltegravir 400 mg dvakrat na dan)
English: 1.5 x 100 mg twice daily *The weight-based dosing recommendation for the chewable tablet, and oral suspension in 10mL of water is based on approximately 6 mg/kg/dose twice daily (see section 5.2).
Slovenian: 1,5 x 100 mg dvakrat na dan *Priporočeni odmerek na podlagi telesne mase za žvečljive tablete in peroralno suspenzijo v 10 ml vode temelji na približno 6 mg/kg/odmerek dvakrat na dan (glejte poglavje 5.2).
English: Isentress contains the active substance raltegravir.
Slovenian: Zdravilo Isentress vsebuje učinkovino raltegravir.
English: Strong inducers of drug metabolizing enzymes (e.g., rifampicin) have not been studied with raltegravir 1,200 mg once daily, but could result in decreased raltegravir trough plasma levels; therefore, co-administration with raltegravir 1,200 mg once daily is not recommended.
Slovenian: Močnih induktorjev encimov, ki presnavljajo zdravila, (npr. rifampicin) skupaj s 1.200 mg raltegravirja enkrat na dan niso raziskali, vendar bi lahko povzročili zmanjšanje najnižje koncentracije raltegravirja v plazmi, zato sočasna uporaba s 1.200 mg raltegravirja enkrat na dan ni priporočljiva.
English: Patients with pre-existing liver dysfunction including chronic hepatitis have an increased frequency of liver function abnormalities during combination anti-retroviral therapy and should be monitored according to standard practice.
Slovenian: Pri bolnikih z že obstoječo okvaro jeter, vključno s kroničnim hepatitisom, so bile nepravilnosti delovanja jeter med kombiniranim protiretrovirusnim zdravljenjem pogostejše.
English: The treatment difference (raltegravir 1,200 mg once daily-raltegravir 400 mg twice daily) was 0.5 % with an associated 95 % CI of (-4.2, 5.2) establishing that raltegravir 1,200 mg once daily is non-inferior to raltegravir 400 mg twice daily.
Slovenian: Razlika med zdravljenjema (1.200 mg raltegravirja enkrat na dan in 400 mg raltegravirja dvakrat na dan) je bila 0,5 % in s 95 % IZ (-4,2; 5,2); kar kaže, da sta shemi 1.200 mg raltegravirja enkrat na dan in 400 mg raltegravirja dvakrat na dan primerljivi.
English: • loss of memory; pain in the hand due to nerve compression; disturbance in attention; dizziness with rapid changes in posture; abnormal taste; increased sleepiness; lack of energy; forgetfulness; migraine headache; loss of feeling, numbness or weakness of the arms and/or legs; tingling; sleepiness; tension headache; tremors; poor quality sleep
Slovenian: • izguba spomina, bolečina v roki zaradi pritiska na živec, motnje pozornosti, omotica po hitri spremembi položaja telesa, nenormalen okus, večja zaspanost, pomanjkanje energije, pozabljivost, migrena, zmanjšana občutljivost za dotik, omrtvelost ali šibkost v rokah in/ali nogah, mravljinčenje, zaspanost, tenzijski glavobol, tresenje, slaba kakovost spanca