FrancophonIA/ELRC3.0 huggingface dataset:
English: Haemophiliac patients should therefore be made aware of the possibility of increased bleeding.
Slovenian: Bolnike s hemofilijo je treba seznaniti z možnostjo, da se zveča nagnjenost h krvavitvam.
English: The tablets should be swallowed whole and not chewed, broken or crushed.
Slovenian: Tablete je treba pogoltniti cele in se jih ne sme žvečiti, prelomiti ali zdrobiti.
English: Antipsychotics/ Neuroleptics
Slovenian: Antipsihotiki/Nevroleptiki
English: Medicinal products that are affected by the use of ritonavir
Slovenian: Zdravila, na katera vpliva uporaba ritonavirja
English: No interaction study is available with ritonavir only.
Slovenian: Študij medsebojnega delovanja samo z ritonavirjem ni na razpolago.
English: In an open label trial completed in 1998 in HIV infected, clinically stable children there was a significant difference (p = 0.03) in the detectable RNA levels in favour of a triple regimen (ritonavir, zidovudine and lamivudine) following 48 weeks treatment.
Slovenian: V odprtem preskušanju, dokončanem leta 1998, s HIV okuženih, klinično stabilnih otrok, so po 48 tednih zdravljenja ugotovili pomembno razliko (p = 0,03) v zaznavni koncentraciji RNA v prid trojne sheme (ritonavir, zidovudin in lamivudin).
English: See also section 2 What you need to know before you or your child takes Ritonavir Mylan.
Slovenian: Glejte tudi poglavje 2, Kaj morate vedeti, preden boste vi ali vaš otrok vzeli zdravilo Ritonavir Mylan.
English: It is therefore important that you remain under the supervision of your doctor while taking Ritonavir Mylan.
Slovenian: Zato je pomembno, da med jemanjem zdravila Ritonavir Mylan ostanete pod nadzorstvom svojega zdravnika.
English: Particular caution should be used when prescribing sildenafil or tadalafil for the treatment of erectile dysfunction in patients receiving ritonavir.
Slovenian: Posebna previdnost je potrebna pri predpisovanju sildenafila ali tadalafila za zdravljenje erektilne disfunkcije bolnikom, ki jemljejo ritonavir.
English: There is a large amount of information on the use of ritonavir (the active ingredient in Ritonavir Mylan) during pregnancy.
Slovenian: O uporabi ritonavirja (zdravilne učinkovine v zdravilu Ritonavir Mylan) med nosečnostjo je veliko podatkov.
English: Co-administration of tipranavir with 200 mg of ritonavir has been associated with reports of clinical hepatitis and hepatic decompensation including some fatalities.
Slovenian: Med sočasno uporabo tipranavirja z 200 mg ritonavirja so bili opisani primeri kliničnega hepatitisa in dekompenzacije jeter, vključno z nekaj smrtnimi primeri.
English: Increased fexofenadine levels may lessen over time as induction develops.
Slovenian: Zvišanje koncentracije feksofenadina se lahko sčasoma zmanjša, ko se razvije indukcija.
English: Other forms of this medicine may be more appropriate for children who have difficulty swallowing tablets.
Slovenian: Za otroke, ki imajo težavo s požiranjem tablet, so morda bolj primerne druge oblike tega zdravila.
English: QTcF interval was evaluated in a randomised, placebo and active (moxifloxacin 400 mg once daily) controlled crossover study in 45 healthy adults, with 10 measurements over 12 hours on Day 3.
Slovenian: Interval QTcF so ocenili v randomizirani, s placebom in zdravilno učinkovino (moksifloksacin 400 mg enkrat na dan) kontrolirani navzkrižni študiji pri 45 zdravih odraslih, ki so jim 3. dan v 12 urah naredili 10 meritev.
English: Ritonavir is likely to change the uterine bleeding profile and reduce the effectiveness of estradiol-containing contraceptives (see section 4.4).
Slovenian: Verjetno je, da bo ritonavir spremenil profil maternične krvavitve in zmanjšal učinkovitost kontraceptivov, ki vsebujejo estradiol (glejte poglavje 4.4).
English: CYP3A4 inhibitors increase the exposure of lomitapide, with strong inhibitors increasing exposure approximately 27-fold.
Slovenian: CYP3A4 zaviralci povečajo izpostavljenost lomitapida, v primeru močnih zaviralcev se izpostavljenost poveča za približno 27-krat.
English: Only when atazanavir with ritonavir is co-administered with efavirenz, a dose increase of ritonavir to 200 mg once daily could be considered.
Slovenian: Kadar je atazanavir z ritonavirjem sočasno uporabljen z efavirencem, je potrebno premisliti o povečanju odmerka ritonavirja na 200 mg enkrat na dan.
English: Steroids
Slovenian: Steroidi
English: If trazodone is co-administered with ritonavir, the combination should be used with caution, initiating trazodone at the lowest dosage and monitoring for clinical response and tolerability.
Slovenian: Če trazodon uporabite sočasno z ritonavirjem, morate kombinacijo uporabljati previdno, trazodon uvesti v najmanjšem odmerku ter kontrolirati bolnikov klinični odziv in prenašanja.
English: For some products, contraindications may be more relevant when ritonavir is used as an antiretroviral agent than when ritonavir is used as a pharmacokinetic enhancer (e.g. rifabutin and voriconazole):
Slovenian: Za nekatera zdravila so kontraindikacije lahko pomembnejše, če je ritonavir uporabljen kot protiretrovirusno zdravilo, kot če je uporabljen kot farmakokinetični stopnjevalec (npr. rifabutin in vorikonazol):
English: The enzyme-modulating effect of ritonavir may be dose dependent.
Slovenian: Vpliv ritonavirja na modulacijo encimov je morda odvisen od odmerka.
English: In cases of co-administration of ritonavir (100 mg twice daily) and indinavir (800 mg twice daily) caution is warranted as the risk of nephrolithiasis may be increased.
Slovenian: Med sočasno uporabo ritonavirja (100 mg dvakrat na dan) in indinavirja (800 mg dvakrat na dan) je potrebna previdnost, kajti poveča se lahko tveganje za nefrolitiazo.
English: Increased plasma concentrations of ergot derivatives leading to acute ergot toxicity, including vasospasm and ischaemia.
Slovenian: Zvišana koncentracija ergotderivatov v plazmi s posledičnimi ergotskimi toksičnimi učinki, vključno z vazospazmom in ishemijo.
English: Ritonavir is a protease inhibitor used to control HIV infection.
Slovenian: Ritonavir je zaviralec proteaze, ki se uporablja za obvladovanje okužbe s HIV.
English: In general, as mutations associated with ritonavir resistance accumulate, susceptibility to select other PIs may decrease due to cross-resistance.
Slovenian: Na splošno se lahko s kopičenjem mutacij, povezanih z odpornostjo proti ritonavirju, zaradi navzkrižne odpornosti zmanjša dovzetnost za izbiro drugih zaviralcev proteaz.
English: Norbuprenorphine Glucuronide metabolites
Slovenian: Norbuprenorfin Presnovki glukuronida
English: If a side effect is preventing you from taking Ritonavir Mylan as directed, tell your doctor straight away.
Slovenian: Če vam neželen učinek prepreči jemanje zdravila Ritonavir Mylan, morate to takoj povedati zdravniku.
English: 117 Allée des Parcs, 69800 Saint-Priest, France
Slovenian: 117 Allée des Parcs, 69800 Saint-Priest, Francija
English: Concomitant use of ritonavir and fluticasone or other glucocorticoids that are metabolised by CYP3A4 is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression (see section 4.5).
Slovenian: Sočasna uporaba ritonavirja in flutikazona ali drugih glukokortikoidov, ki se presnavljajo s CYP3A4, ni priporočljiva, razen če možna korist zdravljenja odtehta tveganje sistemskih učinkov kortikosteroidov, vključno s Cushingovim sindromom in adrenalno supresijo (glejte poglavje 4.5).
English: The inhibitory effect of ritonavir (with or without other protease inhibitors) on P-gp activity may decrease over time (e.g. digoxin and fexofenadine-see table “Ritonavir effects on non-antiretroviral medicinal products” below).
Slovenian: Zaviralni učinek ritonavirja (z drugimi zaviralci proteaz ali brez njih) na aktivnost P-gp se lahko sčasoma zmanjša (npr. digoksin in feksofenadin - glejte spodnjo tabelo “Učinki ritonavirja na neretrovirusna zdravila”).
English: Joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty moving, tell your doctor, as this may be a sign of a problem that can destroy bone (osteonecrosis).
Slovenian: togost sklepov in bolečine (zlasti v kolku, kolenu ali rami) in težave pri gibanju: povejte zdravniku, saj so to lahko znaki motnje, ki povzroča uničenje kosti (osteonekroza).
English: Ritonavir is an orally active peptidomimetic inhibitor of the HIV-1 and HIV-2 aspartyl proteases.
Slovenian: Ritonavir je peroralno aktiven peptidomimetični zaviralec aspartilproteaz HIV-1 in HIV-2.
English: In patients with haemophilia type A and B, there have been reports of increased bleeding while taking this treatment or another protease inhibitor.
Slovenian: Pri bolnikih s hemofilijo tipa A in B so bili med jemanjem tega zdravila ali drugih zaviralcev proteaz opisani primeri povečanih krvavitev.
English: A controlled study completed in 1996 with ritonavir as add-on therapy in HIV-1 infected patients extensively pre-treated with nucleoside analogues and baseline CD4 cell counts ≤ 100 cells/μl showed a reduction in mortality and AIDS defining events.
Slovenian: Kontrolirana študija, dokončana leta 1996, ritonavirja kot dodatnega zdravila pri bolnikih, okuženih s HIV-1, predhodno izdatno zdravljenih z nukleozidnimi analogi in z izhodiščnim številom celic CD4  100 celic/l, je pokazala zmanjšanje umrljivosti in dogodkov, ki opredeljujejo aids.
English: Strong CYP3A4 inhibitors such as protease inhibitors may increase bedaquiline exposure which could potentially increase the risk of bedaquiline-related adverse reactions.
Slovenian: Močni zaviralci CYP3A4 kot so zaviralci proteaz lahko povečajo izpostavljenost bedakilinu, kar bi lahko povečalo tveganje za neželene učinke bedakilina.
English: Ritonavir was noted to be extensively metabolised by the hepatic cytochrome P450 system, primarily by the CYP3A isozyme family and to a lesser extent by the CYP2D6 isoform.
Slovenian: Ugotovljeno je, da se ritonavir izdatno presnavlja s sistemom jetrnega citokroma P450, predvsem z družino izoencimov CYP3A in v manjši meri z izoobliko CYP2D6.
English: Steroids (e.g. dexamethasone, fluticasone propionate, prednisolone, triamcinolone) as ritonavir may raise the blood levels of these medicines which may lead to Cushing's syndrome (development of a rounded face) and reduce production of the hormone cortisol.
Slovenian: Steroide (npr. deksametazon, flutikazonpropionat, prednizolon, triamcinolon), kajti ritonavir lahko zviša koncentracijo teh zdravil v krvi, to pa lahko povzroči Cushingov sindrom (pojav okroglega obraza) in zmanjša nastajanje hormona kortizola.
English: 0.125, single dose
Slovenian: 0,125 posamičen odmerek
English: The mean average change from baseline over 16 weeks for HIV RNA levels was -0.79 log10 (maximum mean decrease: 1.29 log10) in the ritonavir group versus -0.01 log10 in the control group.
Slovenian: Srednja povprečna sprememba v primerjavi z izhodiščno koncentracijo HIV RNA v 16 tednih je bila - 0,79 log10 (največje srednje zmanjšanje: 1,29 log10) v skupini, ki je prejemala ritonavir, v primerjavi z - 0,01 log10 v kontrolni skupini.
English: Trazodone (a medicine for depression) as, unwanted effects like nausea, dizziness, low blood pressure and fainting can occur when taken with ritonavir.
Slovenian: Trazodon (zdravilo proti depresiji), ker se lahko med sočasno uporabo z ritonavirjem pojavijo neželeni učinki, npr. občutek siljenja na bruhanje, omotica, nizek krvni tlak in omedlevica.
English: Multipack: 90 (3 bottles of 30) film-coated tablets
Slovenian: Skupno pakiranje: 90 (3 plastenke po 30) filmsko obloženih tablet
English: No human data on the effect of ritonavir on fertility are available.
Slovenian: Ni podatkov o vplivu ritonavirja na plodnost pri človeku.
English: Thereby, increasing the risk of extreme sedation and respiratory depression from these agents.
Slovenian: S tem se poveča tveganje za čezmerno sedacijo in respiratorno depresijo, ki sta povzročeni s temi zdravili.
English: 600 q12 h Nevirapine Ritonavir Co-administration of ritonavir with nevirapine does not lead to clinically relevant changes in the pharmacokinetics of either nevirapine or ritonavir.
Slovenian: Nevirapin ↔ ↔ Ritonavir ↔ ↔ Sočasna uporaba ritonavirja z nevirapinom ne povzroči klinično pomembnih sprememb v farmakokinetiki nevirapina ali ritonavirja.
English: ↑ 64% ↑ 5 fold
Slovenian: Amprenavir2↑ 64% ↑ 5-krat
English: There are medicines that may not mix with ritonavir because their effects could increase or decrease when taken together.
Slovenian: Nekaterih zdravil ne smete jemati obenem z ritonavirjem, ker se lahko njihovi učinki med sočasno uporabo z ritonavirjem povečajo ali zmanjšajo.
English: The mean average change from baseline over 48 weeks for HIV RNA levels was -0.88 log10 in the ritonavir group versus -0.66 log10 in the ritonavir + zidovudine group versus -0.42 log10 in the zidovudine group.
Slovenian: Srednja povprečna sprememba v primerjavi z izhodiščno koncentracijo HIV RNA v 48 tednih je bila -0,88 log10 v skupini na ritonavirju, -0,66 log10 v skupini na ritonavirju in zidovudinu ter -0,42 log10 v skupini na zidovudinu.
English: Developmental toxicity observed in rats (embryolethality, decreased foetal body weight and ossification delays and visceral changes, including delayed testicular descent) occurred mainly at a maternally toxic dosage.
Slovenian: Toksični učinki na razvoj, ugotovljeni pri podganah (embrioletalnost, zmanjšana fetalna telesna masa, zapoznela osifikacija in visceralne spremembe, vključno z zapoznelo spustitvijo testisov), so se v glavnem pojavili pri odmerkih, toksičnih za samico-mater.
English: Co-administration of ritonavir and medicinal products primarily metabolised by CYP3A may result in increased plasma concentrations of the other medicinal product, which could increase or prolong its therapeutic and adverse effects.
Slovenian: Sočasna uporaba zdravila ritonavirja z zdravili, ki se primarno presnavljajo s CYP3A, lahko poveča koncentracijo drugega zdravila v plazmi, to pa lahko poveča ali podaljša njegove terapevtske in neželene učinke.
English: Increased risk of tumor lysis syndrome at the dose initiation and during the dose-titration phase (see section 4.5).
Slovenian: Povečano tveganje za sindrom tumorske lize pri začetnem odmerjanju in med fazo titracije odmerka (glejte poglavje 4.5).
English: Midazolam is extensively metabolised by CYP3A4.
Slovenian: Midazolam se obsežno presnavlja s pomočjo CYP3A4.
English: 117 Allée des Parcs, Saint-Priest, 69800, France
Slovenian: 117 Allée des Parcs, Saint-Priest, 69800, Francija
English: In HIV-infected patients with severe immune deficiency at the time of institution of combination antiretroviral therapy (CART), an inflammatory reaction to asymtomatic or residual opportunistic pathogens may arise and cause serious clinical conditions, or aggravation of symptoms.
Slovenian: Pri s HIV okuženih bolnikih s hudo imunsko pomanjkljivostjo lahko ob uvedbi kombiniranega protiretrovirusnega zdravljenja (CART - "combination antiretroviral therapy") nastane vnetna reakcija na asimptomatične ali rezidualne oportunistične patogene in povzroči resna klinična stanja ali poslabšanje simptomov.
English: Ritonavir pharmacokinetic parameters have not been studied in patients with renal impairment.
Slovenian: Farmakokinetični parametri ritonavirja niso raziskani pri bolnikih z okvaro ledvic.
English: Animal studies do not indicate harmful effects of ritonavir on fertility (see section 5.3).
Slovenian: Študije na živalih niso pokazale škodljivega vpliva ritonavirja na sposobnost razmnoževanja (glejte poglavje 5.3).
English: Patients should not remain on 300 mg twice daily for more than 3 days.
Slovenian: Odmerka 300 mg dvakrat na dan se ne sme ohranjati več kot 3 dni.
English: Interactions between ritonavir and protease inhibitors, antiretroviral agents other than protease inhibitors and other non-antiretroviral medicinal products are listed in the tables below.
Slovenian: Medsebojna delovanja med ritonavirjem in zaviralci proteaz, protiretrovirusnimi zdravili razen zaviralcev proteaz in neretrovirusnimi zdravili so našteta v spodnjih tabelah.
English: 14-OH clarithromycin metabolite
Slovenian: Klaritromicin presnovek 14-OH klaritromicin
English: Particular caution should be used when prescribing ritonavir in patients using trazodone.
Slovenian: Posebna previdnost je potrebna pri predpisovanju ritonavirja bolnikom, ki uporabljajo trazodon.
English: Clinical investigation in humans has revealed no clinically significant alteration in thyroid function tests.
Slovenian: Klinične raziskave pri ljudeh niso pokazale klinično pomembnih sprememb v preiskavah delovanja ščitnice.
English: There is no specific antidote for overdose with ritonavir.
Slovenian: Za preveliko odmerjanje ritonavirja ni specifičnega antidota.
English: The pharmacokinetics of ritonavir during multiple dose regimens were studied in non-fasting HIV-infected adult volunteers.
Slovenian: Farmakokinetiko ritonavirja so med uporabo shem z večkratnim odmerjanjem raziskovali pri neteščih odraslih prostovoljcih, okuženih s HIV.
English: Serum concentrations of ibrutinib may be increased due to CYP3A inhibition by ritonavir, resulting in increased risk for toxicity including risk of tumor lysis syndrome.
Slovenian: Serumske koncentracije ibrutiniba se lahko povečajo zaradi zavrtja CYP3A z ritonavirjem, posledično se poveča tveganje za toksičnost, vključno s pojavom sindroma tumorske lize.
English: The isopropylthiazole oxidation metabolite (M-2) is the major metabolite and has antiviral activity similar to that of parent compound.
Slovenian: Glavni presnovek je izopropiltiazolski oksidacijski presnovek (M-2); njegova protivirusna aktivnost je podobna protivirusni aktivnosti matične učinkovine.
English: Plasma concentrations of ritonavir after administration of a single 100 mg dose tablet are similar to the 100 mg soft gelatin capsule under fed conditions.
Slovenian: Koncentracija ritonavirja v plazmi je po uporabi 100 mg odmerka v tableti podobna kot po 100 mg odmerku v mehki želatinski kapsuli na poln želodec.
English: Across dose groups, ritonavir oral clearance (CL/F/m2) declined with age with median values of 9.0 L/h/m2 in children less than 3 months of age, 7.8 L/h/m2 in children between 3 and 6 months of age and 4.4 L/h/m2 in children between 6 and 24 months of age.
Slovenian: Mediana vrednost pri otrocih do 3 mesecev starosti je bila 9,0 l/uro/m2, pri otrocih od 3 do 6 mesecev starosti 7,8 l/uro/m2 in pri otrocih od 6 do 24 mesecev starosti 4,4 l/uro/m
English: MARKETING AUTHORISATION NUMBER(S) EU/1/17/1242/004
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/17/1242/004
English: Ritonavir has been shown to cause modest asymptomatic prolongation of the PR interval in some healthy adult subjects.
Slovenian: Ugotovljeno je, da ritonavir nekaterim zdravim odraslim osebam zmerno in asimptomatsko podaljša interval PR.
English: Immunosuppressants Cyclosporine, tacrolimus, everolimus
Slovenian: Ciklosporin, takrolimus, everolimus
English: Clinical trials confirmed the safety and efficacy of 300 mg atazanavir once daily with ritonavir 100 mg once daily in treatment experienced patients.
Slovenian: Klinična preskušanja so potrdila varnost in učinkovitost 300 mg atazanavirja enkrat na dan s 100 mg ritonavirja enkrat na dan za zdravljenje bolnikov, ki so že dobivali terapijo.
English: In a study completed in 1996 recruiting less advanced HIV-1 infected patients (CD4 200-500 cells/μl) without previous antiretroviral therapy, ritonavir in combination with zidovudine or alone reduced viral load in plasma and increased CD4 count.
Slovenian: V študiji, dokončani leta 1996, ki je zajela bolnike z manj napredovalo okužbo s HIV-1 (200-500 celic CD4/l) brez predhodnega protiretrovirusnega zdravljenja, je ritonavir v kombinaciji z zidovudinom ali sam zmanjšal virusno breme v plazmi in zvečal število celic CD4.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported in patients with advanced HIV-disease and/or long-term exposure to combination antiretroviral therapy (CART).
Slovenian: Čeprav je vzrokov verjetno več (vključno z uporabo kortikosteroidov, uživanjem alkohola, hudo imunosupresijo, višjim indeksom telesne mase), so o primerih osteonekroze poročali zlasti pri bolnikih z napredovalo boleznijo HIV ali dolgotrajno izpostavljenostjo kombiniranemu protiretrovirusnemu zdravljenju (CART - combination antiretroviral therapy) ali obojim.
English: Dose of ritonavir (mg)
Slovenian: Odmerek ritonavirja (mg)
English: HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended.
Slovenian: Če je indicirano zdravljenje z zaviralcem reduktaze HMG-CoA, sta priporočljiva pravastatin ali fluvastatin.
English: • if your doctor prescribes a full dose, adults may be started on a dose of 3 tablets in the morning and 3 tablets 12 hours later, gradually increasing over a period of up to 14 days to the full dose of 6 tablets twice daily (totalling 1,200 mg per day).
Slovenian: če zdravnik predpiše polni odmerek, lahko odrasli začnejo jemati 3 filmsko obložene tablete zjutraj in 3 filmsko obložene tablete 12 ur pozneje ter ga nato v obdobju do 14 dni postopoma povečujejo do polnega odmerka 6 filmsko obloženih tablet dvakrat na dan.
English: Renal changes including tubular degeneration, chronic inflammation and proteinurea were noted in rats and are felt to be attributable to species-specific spontaneous disease.
Slovenian: Pri podganah ugotovljene ledvične spremembe, Vključno z degeneracijo tubulov, kroničnim vnetjem in proteinurijo, veljajo za posledico spontane bolezni, specifične za to živalsko vrsto.
English: Pack sizes: 30, 90, 100 and multipack containing 90 (3 bottles of 30) film-coated tablets.
Slovenian: Velikosti pakiranja: 30 , 90, 100 in skupno pakiranje po 90 (3 plastenke po 30) filmsko obloženih tablet.
English: Muscle pain, tenderness or weakness, particularly in combination with antiretroviral therapy including protease inhibitors and nucleoside analogues.
Slovenian: bolečine v mišicah, občutljivost ali šibkost mišic, zlasti v kombinaciji z protiretrovirusnim zdravljenjem, vključno z zaviralci proteaz in nukleozidnimi analogi.
English: If Ritonavir Mylan is taken in combination with other antiretroviral medicines, it is important that you also carefully read the leaflets that are provided with these other medicines.
Slovenian: Če jemljete zdravilo Ritonavir Mylan v kombinaciji z drugimi protiretrovirusnimi zdravili, morate natančno prebrati tudi navodila, priložena tem drugim zdravilom.
English: Patients who exhibit these signs or symptoms should be evaluated and ritonavir therapy should be discontinued if a diagnosis of pancreatitis is made (see section 4.8).
Slovenian: Bolnike s temi znaki oz. simptomi je treba pregledati; če je diagnoza pankreatitisa potrjena, je treba zdravljenje z ritonavirjem prekiniti (glejte poglavje 4.8).
English: Phenytoin may decrease serum levels of ritonavir.
Slovenian: Fenitoin lahko zniža koncentracije ritonavirja v serumu.
English: Ritonavir is not a cure for HIV infection or AIDS.
Slovenian: Ritonavir ne ozdravi okužbe s HIV ali AIDS-a.
English: The recommended dose of ritonavir is 600 mg (6 tablets) twice daily (total of 1,200 mg per day) by mouth.
Slovenian: Odrasli Priporočen odmerek ritonavirja je 600 mg (6 tablet) peroralno dvakrat na dan (skupno 1200 mg na dan).
English: You must not take ritonavir with colchicine if you have kidney and/or liver problems (see also ‘Do not take Ritonavir Mylan' above).
Slovenian: Ritonavirja ne smete uporabljati hkrati s kolhicinom, če imate težave z ledvicami ali jetri (glejte tudi ‘Ne jemljite zdravila Ritonavir Mylan' zgoraj).
English: The following adverse reactions of moderate to severe intensity with possible or probable relationship to ritonavir have been reported.
Slovenian: Opisani so bili naslednji zmerni do hudi neželeni učinki, ki so morda ali verjetno povezani z ritonavirjem.