FrancophonIA/ELRC3.0 huggingface dataset:
English: The diuretic action of hydrochlorothiazide reduces plasma volume, increases plasma renin activity, increases aldosterone secretion, with consequent increases in urinary potassium and bicarbonate loss, and decreases in serum potassium.
Danish: Hydrochlorthiazids diuretiske virkning reducerer plasmavolumen, øger plasmareninaktiviteten, sænker serumkalium og øger aldosteronsekretionen, med deraf følgende øget udskillelse af kalium og bikarbonat i urinen.
English: • Severe renal impairment (creatinine clearance <30 ml/min).
Danish: • Svært nedsat nyrefunktion (kreatinin-clearance < 30 ml/min)
English: The concomitant use of Kinzalkomb with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 ml/min/1.73 m2) (see sections 4.5 and 5.1).
Danish: Samtidig brug af Kinzalkomb og lægemidler indeholdende aliskiren er kontraindiceret hos patienter med diabetes mellitus eller nedsat nyrefunktion (GFR < 60 ml/min/1,73 m2) (se pkt.
English: Thiazides should be discontinued before carrying out tests for parathyroid function.
Danish: Thiaziderne skal seponeres, inden der foretages undersøgelser af biskjoldbruskkirtlernes funktion.
English: There are no adequate data from the use of Kinzalkomb in pregnant women.
Danish: Der er utilstrækkelige data fra anvendelse af telmisartan til gravide kvinder.
English: Thiazides have been shown to increase the urinary excretion of magnesium, which may result in hypomagnesaemia (see section 4.5).
Danish: Det har vist sig, at thiazider øger magnesiumudskillelsen i urinen, hvilket kan resultere i hypomagnesiæmi (se pkt.
English: Telmisartan blocks the effect of angiotensin II so that the blood vessels relax, and your blood pressure is lowered.
Danish: Telmisartan blokerer angiotensin IIs virkning, så blodkarrene afslappes og blodtrykket falder.
English: Untreated acute angle-closure glaucoma can lead to permanent vision loss.
Danish: Ubehandlet akut snævervinklet glaukom kan føre til permanent synstab.
English: In patients with impaired renal function the rate of hydrochlorothiazide elimination is reduced.
Danish: Hos patienter med nedsat nyrefunktion reduceres hastigheden af udskillelsen af hydrochlorthiazid.
English: Previous preclinical safety studies performed with co-administration of telmisartan and hydrochlorothiazide in normotensive rats and dogs, in doses producing exposure comparable to that in the clinical therapeutic range, caused no additional findings not already observed with administration of either substance alone.
Danish: I prækliniske sikkerhedsforsøg med samtidig indgift af telmisartan og hydrochlorthiazid i normotensive rotter og hunde i doser, der gav en eksponering sammenlignelig med den i det kliniskterapeutiske område, fandt man ikke andre resultater end dem, der allerede var set ved indgift af de to stoffer hver for sig.
English: In the "Prevention Regimen For Effectively avoiding Second Strokes" (PRoFESS) trial in patients 50 years and older, who recently experienced stroke, an increased incidence of sepsis was noted for telmisartan compared with placebo, 0.70 % vs. 0.49 % [RR 1.43 (95 % confidence interval 1.002.06)]; the incidence of fatal sepsis cases was increased for patients taking telmisartan (0.33 %) vs. patients taking placebo (0.16 %) [RR 2.07 (95 % confidence interval 1.14 - 3.76)].
Danish: I forsøget "Prevention Regimen For Effectively avoiding Second Strokes" (PRoFESS) hos patienter på 50 år og ældre, som for nylig har oplevet stroke, blev der observeret en øget incidens af sepsis hos patienter behandlet med telmisartan sammenlignet med placebo, 0,70 % vs. 0,49 % [RR 1,43 (95 % sikkerhedsinterval 1,00-2,06)]; incidensen af letale sepsistilfælde var øget hos patienter, som fik telmisartan (0,33 %) vs. patienter, som fik placebo (0,16 %) [RR 2,07 (95 % sikkerhedsinterval 1,14-3,76)].
English: Hydrochlorothiazide, a sulfonamide, can cause an idiosyncratic reaction, resulting in acute transient myopia and acute angle-closure glaucoma.
Danish: Hydrochlorthiazid, som er et sulfonamid, kan forårsage en idiosynkratisk reaktion, der kan resultere i akut forbigående nærsynethed og akut snævervinklet glaukom.
English: Presumably through blockade of the reninangiotensin-aldosterone system, co-administration of telmisartan tends to reverse the potassium loss associated with these diuretics.
Danish: Sandsynligvis pga. blokering af renin-angiotensin-aldosteronsystemet synes telmisartan at modvirke det kaliumtab, der er forbundet med disse diuretika.
English: Anaemia Eosinophilia, thrombocytopenia
Danish: Anæmi Eosinofili, trombocytopeni
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS Blister of 7 tablets
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTER ELLER STRIP Blisterkort med 7 tabletter
English: The most commonly reported adverse reaction is dizziness.
Danish: Den almindeligst rapporterede bivirkning er svimmelhed.
English: Both substances help to control high blood pressure.
Danish: Begge lægemiddelstoffer anvendes til at sænke forhøjet blodtryk.
English: Kinzalkomb is a combination of an angiotensin II receptor antagonist, telmisartan, and a thiazide diuretic, hydrochlorothiazide.
Danish: Kinzalkomb er en kombination af en angiotensin II-receptorantagonist, telmisartan og thiazidet hydrochlorthiazid.
English: As with other vasodilators, special caution is indicated in patients suffering from aortic or mitral stenosis, or obstructive hypertrophic cardiomyopathy.
Danish: Som ved brug af andre vasodilatatorer bør særlig forsigtighed udvises hos patienter, der lider af aortaeller mitralstenose eller obstruktiv hypertrofisk kardiomyopati.
English: Hydrochlorothiazide exhibits linear pharmacokinetics.
Danish: Hydrochlorthiazid udviser lineær farmakokinetik.
English: If hypotension occurs, the patient should be placed in a supine position, with salt and volume replacements given quickly.
Danish: Ved hypotension skal patienten lægges i rygleje, og der skal hurtigt gives salt- og væskesubstitution.
English: Kinzalkomb may increase the blood pressure lowering effect of other medicines used to treat high blood pressure or of medicines with blood pressure lowering potential (e.g. baclofen, amifostine).
Danish: Kinzalkomb kan øge den blodtrykssænkende virkning, både af anden blodtrykssænkende medicin og af medicin, der potentielt kan sænke blodtrykket (f.eks. baclofen eller amifostin).
English: Overdose with hydrochlorothiazide is associated with electrolyte depletion (hypokalaemia, hypochloraemia) and hypovolaemia resulting from excessive diuresis.
Danish: Overdosering med hydrochlorthiazid medfører elektrolytforstyrrelser (hypokaliæmi, hypokloræmi) og hypovolæmi pga. overdreven diurese.
English: Angioedema (also with fatal outcome), erythema, pruritus, rash, hyperhidrosis, urticaria
Danish: Angioødem (også med letalt udfald), erytem, prutitus, udslæt, hyperhidrose, urticaria
English: Anorexia, appetite decreased, electrolyte imbalance, hypercholesterolaemia, hyperglycaemia, hypovolaemia.
Danish: Anoreksi, nedsat appetit, forstyrrelser i elektrolytbalancen, hyperkolesterolæmi, hyperglykæmi, hypovolæmi
English: Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of drug initiation.
Danish: Symptomerne kan være akut synsnedsættelse eller øjensmerter og opstår sædvanligvis indenfor få timer til uger efter første indtagelse af lægemidlet.
English: Anaphylactic reactions, hypersensitivity
Danish: Anafylaktiske reaktioner, overfølsomhed
English: These medicinal products may potentiate the effect of hydrochlorothiazide on serum potassium (see section 4.4).
Danish: Disse lægemidler kan øge hydrochlorthiazids påvirkning af serumkalium (se pkt.
English: Investigations Rare:
Danish: Undersøgelser Sjælden:
English: Contact your doctor, pharmacist, or your nearest hospital emergency department immediately.
Danish: Kontakt straks lægen, skadestuen eller apoteket.
English: Do not take Kinzalkomb
Danish: Tag ikke Kinzalkomb
English: Very rare side effects (may affect up to 1 in 10,000 people): Increased pH (disturbed acid-base balance) due to low blood chloride level.
Danish: Meget sjældne bivirkninger (kan forekomme hos op til 1 ud af 10.000 brugere): Forhøjet pH-værdi (forstyrrelse i syre-base-balancen) på grund af lavt kloridindhold i blodet.
English: Syncope, paraesthesia Insomnia, sleep disorders
Danish: Synkope, paræstesi Søvnløshed, søvnforstyrrelser
English: Although clinically significant hyperkalaemia has not been documented with Kinzalkomb, risk factors for the development of hyperkalaemia include renal insufficiency and/or heart failure, and diabetes mellitus.
Danish: Skønt der ikke er set nogen klinisk signifikant hyperkaliæmi i forbindelse med Kinzalkomb, så omfatter risikofaktorerne for udvikling af hyperkaliæmi blandt andet nyreinsufficiens og/eller hjertesvigt samt diabetes mellitus.
English: High HCTZ use (≥50,000 mg cumulative) was associated with an adjusted OR of 1.29 (95% CI: 1.231.35) for BCC and 3.98 (95% CI: 3.68-4.31) for SCC.
Danish: Stort forbrug af hydrochlorthiazid (≥ 50.000 mg kumulativt) var forbundet med en justeret OR-værdi på 1,29 (95 %-KI: 1,23-1,35) for basalcellekarcinom og på 3,98 (95 %-KI: 3,68-4,31) for pladecellekarcinom.
English: Talk to your doctor before taking Kinzalkomb if you are suffering or have ever suffered from any of the following conditions or illnesses:
Danish: Kontakt lægen, før du tager Kinzalkomb, hvis du har eller har haft en medicinsk lidelse eller sygdom, især hvis det er en af dem, der er nævnt nedenfor:
English: In patients whose vascular tone and renal function depend predominantly on the activity of the reninangiotensin-aldosterone system (e.g. patients with severe congestive heart failure or underlying renal disease, including renal artery stenosis), treatment with medicinal products that affect this system has been associated with acute hypotension, hyperazotaemia, oliguria, or rarely acute renal failure (see section 4.8).
Danish: Hos patienter, hvis vaskulære tonus og nyrefunktion overvejende afhænger af renin-angiotensin-aldosteronsystemets aktivitet (fx patienter med svær højresidig hjerteinsufficiens eller tilgrundliggende nyresygdom, herunder nyrearteriestenose), har behandling med lægemidler, som påvirker dette system, været forbundet med akut hypotension, hyperazotæmi, oliguri eller i sjældne tilfælde akut nyresvigt (se pkt.
English: In patients with mild to moderate hepatic impairment the posology should not exceed Kinzalkomb 40 mg/12.5 mg once daily.
Danish: Hos patienter med let eller moderat nedsat leverfunktion bør dosis ikke overskride Kinzalkomb 40 mg/12,5 mg én gang daglig.
English: Hydrochlorothiazide may cause or exacerbate hypovolaemia which could lead to electrolyte imbalance (see section 4.4).
Danish: Hydrochlorthiazid kan forårsage eller forværre hypovolæmi, som kan føre til elektrolytforstyrrelser (se pkt.
English: If this combination proves essential, careful monitoring of serum lithium level is recommended during concomitant use.
Danish: Hvis denne kombination skønnes nødvendig, tilrådes tæt monitorering af serum-lithium.
English: Chest pain Influenza-like illness, pain
Danish: Brystsmerter Influenzalignende symptomer, smerter
English: Although hypokalaemia may develop with the use of thiazide diuretics, concurrent therapy with telmisartan may reduce diuretic-induced hypokalaemia.
Danish: Hypokaliæmi kan forkomme ved anvendelse af thiaziddiuretika, men samtidig behandling med telmisartan kan reducere den diuretika-inducerede hypokaliæmi.
English: Based on their pharmacological properties it can be expected that the following medicinal product may potentiate the hypotensive effects of all antihypertensives including telmisartan: Baclofen, amifostine.
Danish: Følgende præparater har farmakologiske egenskaber, der kan forventes at forstærke den hypotensive effekt af alle antihypertensiva, herunder telmisartans: Baclofen, amifostin.
English: As with all other angiotensin II receptor antagonists, telmisartan is apparently less effective in lowering blood pressure in black patients than in non blacks, possibly because of higher prevalence of low renin states in the black hypertensive population.
Danish: Som ved alle andre angiotensin II-receptorantagonister synes telmisartan at virke mindre blodtrykssænkende hos negroide end hos ikke-negroide personer.
English: The risk of hypokalaemia is greater in patients with cirrhosis of liver, in patients experiencing brisk diuresis, in patients who are receiving inadequate oral intake of electrolytes and in patients receiving concomitant therapy with corticosteroids or Adrenocorticotropic hormone (ACTH) (see section 4.5).
Danish: Der er større risiko for at få hypokaliæmi for patienter med levercirrose, med kraftig diurese eller med for lille indtag af elektrolytter samt for patienter, der får kortikosteroider eller adrenokortikotropt hormon (ACTH) (se pkt.
English: Co-administration of lithium and Kinzalkomb is not recommended (see section 4.4).
Danish: Samtidig administration af lithium og Kinzalkomb kan ikke anbefales (se pkt.
English: Thiazides may reduce the renal excretion of cytotoxic medicinal products and potentiate their myelosuppressive effects.
Danish: Thiazider kan formindske cytotoksiske lægemidlers udskillelse gennem nyrerne og forstærke deres myelosuppressive virkning.
English: Kinzalkomb should be taken in patients whose blood pressure is not adequately controlled by telmisartan alone.
Danish: Kinzalkomb gives, hvis blodtrykket ikke kan reguleres tilfredsstillende med telmisartan alene.
English: TRANSCEND randomized ACE-I intolerant patients with otherwise similar inclusion criteria as ONTARGET to telmisartan 80 mg (n=2954) or placebo (n=2972), both given on top of standard care.
Danish: I TRANSCEND-studiet randomiseredes patienter, der var intolerante over for ACE-hæmmere, men i øvrigt med de samme inklusionskriterier som i ONTARGET-studiet, til enten 80 mg telmisartan (n = 2.954) eller placebo (n = 2.972).
English: Xanthopsia, acute myopia, acute angle-closure glaucoma
Danish: Xantopsi, akut myopi, akut snævervinklet glaukom
English: - Low blood pressure (hypotension), likely to occur if you are dehydrated (excessive loss of body water) or have salt deficiency due to diuretic therapy (water tablets), low-salt diet, diarrhoea, vomiting, or haemodialysis.
Danish: • Lavt blodtryk (hypotension), som kan forekomme, når du er dehydreret (har for lidt kropsvæske) eller har saltmangel på grund af enten vanddrivende medicin, saltfattig diæt, diarré, opkastning eller hæmodialyse.
English: If you are intolerant to some sugars, consult your doctor before taking Kinzalkomb.
Danish: Hvis du ikke tåler disse sukkerarter, bør du kontakte din læge, før du tager Kinzalkomb.
English: You should also tell your doctor, if you experience an increased sensitivity of the skin to the sun with symptoms of sunburn (such as redness, itching, swelling, blistering) occurring more quickly than normal.
Danish: Fortæl din læge, hvis du ved solbadning hurtigere end ellers oplever symptomer på solskoldning (såsom rødme, kløe, hævelse, blærer).
English: Kinzalkomb 80 mg/12.5 mg tablets EU/1/02/214/006-010
Danish: Kinzalkomb 80 mg/12,5 mg tabletter EU/1/02/214/006-010
English: Telmisartan: The pharmacokinetics of orally administered telmisartan are non-linear over doses from 20 - 160 mg with greater than proportional increases of plasma concentrations (Cmax and AUC) with increasing doses.
Danish: Telmisartan: Farmakokinetikken ved oralt indgivet telmisartan er ikke-lineær ved doser på 20-160 mg, idet der ved stigende doser ses overproportionale stigninger af plasmakoncentrationen (Cmax og AUC).
English: The tablets should be swallowed with some water or other non-alcoholic drink.
Danish: Tabletten synkes sammen med vand eller en anden væske.
English: You should store your medicine in the original package in order to protect the tablets from moisture.
Danish: Du skal opbevare Kinzalkomb i den originale yderpakning for at beskytte tabletterne mod fugt.
English: Kinzalkomb is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not controlled enough when telmisartan is used alone.
Danish: Kinzalkomb bruges til at sænke forhøjet blodtryk (essentiel hypertension) hos voksne, hvis blodtryk ikke er sænket tilstrækkeligt med telmisartan.
English: Thiazides, including hydrochlorothiazide, can cause fluid or electrolyte imbalance (including hypokalaemia, hyponatraemia and hypochloraemic alkalosis).
Danish: Thiazider, herunder hydrochlorthiazid, kan forårsage forstyrrelser i væske- eller elektrolytbalancen (bl.a. hypokaliæmi, hyponatriæmi og hypochloræmisk alkalose).
English: Gastrointestinal disorders
Danish: Gastrointestinalt ubehag
English: Non-steroidal anti-inflammatory medicinal products NSAIDs (i.e. acetylsalicylic acid at anti-inflammatory dosage regimens, COX-2 inhibitors and nonselective NSAIDs) may reduce the diuretic, natriuretic and antihypertensive effects of thiazide diuretics and the antihypertensive effects of angiotensin II receptor antagonists.
Danish: Non-steroide anti-inflammatoriske lægemidler (NSAID) NSAID (f.eks. acetylsalicylsyre (ASA) i doser beregnet til anti-inflammatorisk behandling, COX-2hæmmere og ikke-selektive NSAID) kan hos nogle patienter nedsætte den diuretiske, natriuretiske og antihypertensive virkning af thiaziddiuretika og den antihypertensive virkning af angiotensin IIreceptorantagonister.
English: Hypochloraemic alkalosis
Danish: Hypochloræmisk alkalose
English: Very rare side effects (may affect up to 1 in 10,000 people): Progressive scarring of lung tissue (interstitial lung disease) **
Danish: Meget sjældne bivirkninger (kan forekomme hos op til 1 ud af 10.000 brugere): Tiltagende arvævsdannelse i lungerne (interstitiel lungesygdom)**
English: Beta-blockers and diazoxide
Danish: Betablokkere og diazoxid
English: What Kinzalkomb contains
Danish: Kinzalkomb indeholder:
English: Thiazide-induced hypokalaemia or hypomagnesaemia favours the onset of digitalis-induced arrhythmia (see section 4.4).
Danish: Thiazidbetinget hypokaliæmi eller hypomagnesiæmi øger forekomsten af digitalis-inducerede arytmier (se pkt.
English: LIST OF EXCIPIENTS Contains lactose monohydrate and sorbitol (E420).
Danish: LISTE OVER HJÆLPESTOFFER Indeholder lactosemonohydrat og sorbitol (E420).
English: Kinzalkomb is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Danish: Det frarådes at anvende Kinzalkomb under graviditeten, og det må ikke tages senere end 3 måneder henne i graviditeten, da det kan forårsage alvorlige fosterskader.
English: Medicines that are affected by changes of the blood potassium level such as heart medicines (e.g. digoxin) or medicines to control the rhythm of your heart (e.g. quinidine, disopyramide, amiodarone, sotalol), medicines used for mental disorders (e.g. thioridazine, chlorpromazine, levomepromazine) and other medicines such as certain antibiotics (e.g. sparfloxacine, pentamidine) or certain medicines to treat allergic reactions (e.g. terfenadine).
Danish: - Medicin, der påvirkes af ændringer i kaliumindholdet i blodet, såsom hjertemedicin (f.eks. digoxin) eller medicin til at kontrollere hjerterytmen (f.eks. quinidin, disopyramid, amiodaron, sotalol), medicin, som bruges til psykiske lidelser (f.eks. thioridazin, chlorpromazin, levomepromazin) og andre lægemidler, såsom visse antibiotika (f.eks sparfloxacin, pentamidin) eller visse lægemidler til behandling af allergiske reaktioner (f.eks terfenadin).
English: Kinzalkomb must not be used in patients with severe renal impairment (creatinine clearance <30 ml/min) (see section 4.3).
Danish: Kinzalkomb må ikke anvendes til patienter med svært nedsat nyrefunktion (kreatinin-clearance <30 ml/min).
English: Toxicological findings also well known from preclinical studies with angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists were: a reduction of red cell parameters (erythrocytes, haemoglobin, haematocrit), changes of renal haemodynamics (increased blood urea nitrogen and creatinine), increased plasma renin activity, hypertrophy/hyperplasia of the juxtaglomerular cells and gastric mucosal injury.
Danish: Toksikologiske fund, som også er kendt fra prækliniske forsøg med "angiotensin converting enzyme"hæmmere og angiotensin II-receptor-antagonister, var: Fald i røde blodcelleparametre (erytrocytter, hæmoglobin, hæmatokrit), ændringer i den renale hæmodynamik (forhøjet urea N i serum (BUN) og kreatinin), forøget plasmareninaktivitet, hypertrofi/hyperplasi af de juxtaglomerulære celler og gastriske slimhindelæsioner.
English: There is no experience regarding the administration of Kinzalkomb in patients with recent kidney transplantation.
Danish: Der er ingen erfaring med anvendelse af Kinzalkomb til patienter, der kort tid forinden har fået foretaget en nyretransplantation.
English: As with any antihypertensive agent, excessive reduction of blood pressure in patients with ischaemic cardiopathy or ischaemic cardiovascular disease could result in a myocardial infarction or stroke.
Danish: Som ved andre antihypertensiva kan en for kraftig reduktion af blodtrykket hos patienter med iskæmisk kardiopati eller iskæmisk kardiovaskulær sygdom resultere i myokardieeinfarkt eller apopleksi (slagtilfælde).
English: For the foetotoxic potential of the telmisartan/hydrochlorothiazide combination see section 4.6.
Danish: Med hensyn til en potentiel føtotoksisk effekt af telmisartan/hydrochlorthiazid-kombinationen henvises til pkt.
English: If these medicinal products are to be prescribed with the hydrochlorothiazide-telmisartan combination, monitoring of potassium plasma levels is advised.
Danish: Hvis disse medikamenter gives sammen med hydrochlorthiazid-telmisartan-kombinationen, tilrådes monitorering af kalium-plasmaniveauet.
English: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with angiotensin converting enzyme inhibitors.
Danish: Der er rapporteret reversible stigninger i serum-lithiumkoncentrationerne samt toksicitet ved samtidig behandling med lithium og ACE-hæmmere.
English: Cholestyramine and colestipol resins
Danish: Colestyramin og colestipolresiner
English: Telmisartan In patients taking telmisartan alone the following additional side effects have been reported:
Danish: Telmisartan Hos patienter, der kun får telmisartan, er der i tillæg til ovenstående set følgende bivirkninger:
English: Telmisartan is not removed from blood by haemodialysis.
Danish: Telmisartan fjernes ikke fra blodet med hæmodialyse.
English: Concomitant administration of hydrochlorothiazide and telmisartan does not appear to affect the pharmacokinetics of either substance in healthy subjects.
Danish: Samtidig indgift af hydrochlorthiazid og telmisartan har hos raske personer ingen indflydelse på de to lægemidlers farmakokinetik
English: The elimination half-life is not changed in patients with hepatic impairment.
Danish: Elimineringshalveringstiden er uændret hos patienter med nedsat leverfunktion.
English: Nondepolarizing skeletal muscle relaxants (e.g. tubocurarine) The effect of nondepolarizing skeletal muscle relaxants may be potentiated by hydrochlorothiazide.
Danish: Ikke-depolariserende muskelrelaksantia (fx tubocurarin) Virkningen af ikke-depolariserende muskelrelaksantia kan forstærkes af hydrochlorthiazid.
English: Endocrine disorders Not known:
Danish: Det endokrine system Ikke kendt:
English: Anti-cholinergic medicines (medicines used to treat a variety of disorders such as gastrointestinal cramps, urinary bladder spasm, asthma, motion sickness, muscular spasms, Parkinson's disease and as an aid to anaesthesia) such as atropine and biperiden.
Danish: - Anti-cholinerge lægemidler (medicin til behandling af en række forskellige lidelser, såsom mavekramper, urinblære spasmer, astma, transportsyge, muskelkramper, Parkinsons sygdom og som en hjælp til bedøvelse) såsom atropin og biperiden.