FrancophonIA/ELRC3.0 huggingface dataset:
English: Active substances known to induce CYP2C19 or CYP3A4 or both (such as rifampicin and St John's wort) may lead to decreased omeprazole serum levels by increasing omeprazole's rate of metabolism.
Slovenian: Zdravilne učinkovine, ki inducirajo CYP2C19, CYP3A4 ali oba (npr. rifampicin in šentjanževka), lahko zmanjšajo koncentracijo omeprazola v serumu, ker povečajo hitrost njegove presnove.
English: This should be considered in patients with reduced body stores or risk factors for reduced vitamin B12 absorption on long-term therapy.
Slovenian: To je treba upoštevati pri dolgotrajnem zdravljenju bolnikov z zmanjšano telesno zalogo vitamina B12 ali z dejavniki tveganja za zmanjšano absorpcijo tega vitamina.
English: For patients with swallowing difficulties and for children who can drink or swallow semi-solid food Patients can open the capsule and swallow the contents with half a glass of water or after mixing the contents in a slightly acidic fluid e.g., fruit juice or applesauce, or in non-carbonated water.
Slovenian: Bolniki, ki težko požirajo, in otroci, ki lahko pijejo ali požirajo poltrdo hrano Bolnik lahko kapsulo odpre in njeno vsebino zaužije s pol kozarca vode, ali po premešanju vsebine z rahlo kislo tekočino, npr. sadnim sokom, čežano ali negazirano vodo.
English: The AUC of omeprazole increases with repeated administration due to a decrease of systemic clearance probably caused by an inhibition of the CYP2C19 enzyme by omeprazole and/or its metabolites (e.g. the sulphone).
Slovenian: AUC omeprazola se s ponavljajočo uporabo povečuje zaradi zmanjšanja sistemskega očistka; vzrok tega je verjetno zavrtje encima CYP2C19 z omeprazolom in/ali njegovimi presnovki (npr. s sulfonom).
English: • Children over 1 year of age and with a body weight of more than 10 kg may take Losec.
Slovenian: • Otroci, ki so starejši od 1 leta in tehtajo več kot 10 kg, lahko jemljejo zdravilo Losec.
English: • Skin rash on exposure to sunshine.
Slovenian: • izpuščaj na koži po izpostavljenosti soncu
English: • You pass black stools (blood-stained faeces).
Slovenian: • Iztrebljate črno (krvavo obarvano) blato.
English: Gastro-resistant tablets
Slovenian: gastrorezistentne tablete
English: 10 tablets (10 mg only) 14 tablets
Slovenian: 10 tablet (samo 10 mg) 14 tablet
English: Your doctor will decide whether you can take Losec during this time.
Slovenian: Zdravnik bo presodil, ali lahko med tem časom jemljete zdravilo Losec.
English: Irreversible visual impairment has been reported in isolated cases of critically ill patients who have received omeprazole intravenous injection, especially at high doses, but no causal relationship has been established.
Slovenian: Opisani so posamezni primeri ireverzibilne okvare vida pri kritičnih bolnikih, ki so dobili omeprazol v intravenski injekciji, zlasti v velikih odmerkih, toda vzročna povezanost ni ugotovljena.
English: Your doctor may increase the dose to 40 mg once a day.
Slovenian: Zdravnik vam odmerek lahko poveča na 40 mg enkrat na dan.
English: Omeprazole, as all acid-blocking medicines, may reduce the absorption of vitamin B12 (cyanocobalamin) due to hypo- or achlorhydria.
Slovenian: Kot vsa zdravila, ki zavirajo izločanje kisline, lahko tudi omeprazol zaradi hipo- ali aklorhidrije zmanjša absorpcijo vitamina B12 (cianokobalamina).
English: • Swallow your tablets whole with half a glass of water.
Slovenian: • Tablete pogoltnite cele s pol kozarca vode.
English: Effects of omeprazole on the pharmacokinetics of other active substances
Slovenian: Vpliv omeprazola na farmakokinetiko drugih zdravilnih učinkovin
English: The interaction may also involve CYP2C19 inhibition.
Slovenian: Medsebojno delovanje morda vključuje tudi zavrtje CYP2C19.
English: • Tacrolimus (in cases of organ transplantation)
Slovenian: • takrolimus (uporablja se pri presaditvi organov).
English: Losec is used in adults for the short-term treatment of reflux symptoms (for example, heartburn, acid regurgitation).
Slovenian: Zdravilo Losec se uporablja pri odraslih za kratkotrajno zdravljenje simptomov refluksa (npr. zgage, regurgitacije kisline).
English: This time- and dosedependency is due to a decrease of first pass metabolism and systemic clearance probably caused by an inhibition of the CYP2C19 enzyme by omeprazole and/or its metabolites (e.g. the sulphone).
Slovenian: Ta odvisnost od časa in odmerka je posledica manjše presnove prvega prehoda in sistemskega očistka omeprazola; vzrok je verjetno zavrtje encima CYP2C19 z omeprazolom in/ali njegovimi presnovki (npr. s sulfonom).
English: • You can take your tablets with food or on an empty stomach.
Slovenian: • Tablete lahko vzamete s hrano ali na prazen želodec.
English: Leukopenia, thrombocytopenia
Slovenian: levkopenija, trombocitopenija
English: For posaconazol and erlotinib concomitant use should be avoided.
Slovenian: Sočasni uporabi posakonazola in erlotiniba se je treba izogniti.
English: The stability of omeprazole is influenced by the pH of the solution for infusion, which is why no other solvent or quantities should be used for dilution.
Slovenian: Na stabilnost omeprazola vpliva pH raztopine za infundiranje in to je razlog, da se za razredčenje ne sme uporabiti drugega vehikla ali količine.
English: Aluminium blister.
Slovenian: Aluminijski pretisni omot
English: Losec is not likely to affect your ability to drive or use any tools or machines.
Slovenian: Ni verjetno, da bi zdravilo Losec vplivalo na vašo sposobnost za upravljanje vozil ali strojev.
English: Vial of 10 ml made of colourless borosilicate glass, type I. Stopper made of bromobutyl rubber, cap made of aluminium and a plastic polypropylene lid.
Slovenian: 10-ml viale iz brezbarvnega borosilikatnega stekla tipa I. Zamašek je izdelan iz bromobutilne gume, zaporka iz aluminija in plastičen polipropilenski pokrovček.
English: Posology in adults
Slovenian: Odmerjanje pri odraslih
English: After repeated once-daily administration, the bioavailability increases to about 60%.
Slovenian: Po večkratnem odmerjanju enkrat na dan se biološka uporabnost poveča na približno
English: As in all long-term treatments, especially when exceeding a treatment period of 1 year, patients should be kept under regular surveillance.
Slovenian: Bolnike je treba redno kontrolirati, tako kot med vsakim dolgotrajnim zdravljenjem; to še zlasti velja, če je zdravljenje daljše od 1 leta.
English: H. pylori eradication in peptic ulcer disease
Slovenian: Odprava H. pylori pri peptični ulkusni bolezni
English: • If the ulcer do not fully heal, the dose can be increased to 40 mg once a day for 8 weeks.
Slovenian: • Če se vam razjeda ne pozdravi povsem, je odmerek mogoče povečati na 40 mg enkrat na dan za nadaljnjih 8 tednov.
English: They work by reducing the amount of acid that your stomach produces.
Slovenian: Ta zdravila delujejo tako, da zmanjšajo nastajanje kisline v želodcu.
English: Eradication of H. pylori in children
Slovenian: Odprava H. pylori pri otrocih
English: If you are given more Losec than you should If you think you have been given too much Losec, talk to your doctor straight away.
Slovenian: Če dobite večji odmerek zdravila Losec, kot bi smeli Če menite, da ste dobili preveč zdravila Losec, se nemudoma posvetujte z zdravnikom.
English: lansoprazole, rabeprazole, esomeprazole).
Slovenian: lansoprazol, rabeprazol, esomeprazol);
English: In children younger than 6 months, clearance of omeprazole is low due to low capacity to metabolise omeprazole.
Slovenian: Zaradi majhne sposobnosti za presnovo omeprazola je očistek omeprazola pri otrocih, mlajših od 6 mesecev, majhen.
English: 700 capsules
Slovenian: 700 kapsul
English: • Store this blister in the original package or keep the bottle tightly closed in order to protect from moisture.
Slovenian: • Shranjujte ta pretisni omot v originalnem pakiranju oz. shranjujte plastenko tesno zaprto za zagotovitev zaščite pred vlago.
English: • Effects on your stomach or gut: diarrhoea, stomach pain, constipation, wind (flatulence).
Slovenian: • učinki na želodec in črevo: driska, bolečine v želodcu, zaprtost, vetrovi
English: • You get stomach pain or indigestion.
Slovenian: • Pojavijo se vam bolečine v želodcu ali težave z želodcem.
English: • Dry mouth.
Slovenian: • vnetje v ustih
English: This may cause weakness, being sick (vomiting) and cramps.
Slovenian: To lahko povzroči šibkost, bruhanje in krče.
English: • Sudden wheezing, swelling of your lips, tongue and throat or body, rash, fainting or difficulties in swallowing (severe allergic reaction).
Slovenian: • Nenadno piskajoče dihanje, oteklost ustnic, jezika in žrela ali telesa, izpuščaj, omedlevico ali težave s požiranjem ( huda alergijska reakcija).
English: Co-administration of omeprazole (40 mg once daily) reduced mean nelvinavir exposure by ca. 40% and the mean exposure of the pharmacologically active metabolite M8 was reduced by ca. 75 -90%.
Slovenian: Uporaba omeprazola (40 mg enkrat na dan) je zmanšala povprečno izpostavljenost nelfinavirju za približno 40 % in povprečno izpostavljenost farmakološko aktivnemu presnovku M8 za približno 75 do 90 %.
English: H. pylori is associated with peptic ulcer disease, including duodenal and gastric ulcer disease.
Slovenian: H. pylori je povezan s peptično ulkusno boleznijo, vključno z ulkusno boleznijo na dvanajstniku in želodcu.
English: POSSIBLE SIDE EFFECTS Like all medicines, Losec can cause side effects, although not everybody gets them.
Slovenian: MOŽNI NEŽELENI UČINKI Kot vsa zdravila ima lahko tudi zdravilo Losec neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Irreversible visual impairment has been reported in isolated cases of critically ill patients who have received Losec intravenous injection, especially at high doses, but no causal relationship has been established.
Slovenian: Opisani so posamezni primeri ireverzibilne okvare vida pri kritičnih bolnikih, ki so dobili Losec v intravenski injekciji, zlasti v velikih odmerkih, toda vzročna povezanost ni ugotovljena.
English: Side effects such as dizziness and visual disturbances may occur (see section 4).
Slovenian: Pojavijo se lahko neželeni učinki, npr. omotica ali motnje vida (glejte poglavje 4).
English: Sodium chloride 9 mg/ml (0.9%) solution for infusion or glucose 50 mg/ml (5%) solution for infusion must be used.
Slovenian: Uporabiti je treba 0,9 % (9 mg/ml) raztopino natrijevega klorida za infundiranje ali 5 % (50 mg/ml) raztopino glukoze za infundiranje.
English: Adverse drug reactions such as dizziness and visual disturbances may occur (see section 4.8).
Slovenian: Pojavijo se lahko neželeni učinki, npr. omotica ali motnje vida (glejte poglavje 4.8).
English: • Reddening of the skin with blisters or peeling.
Slovenian: • Pordelost kože z mehurji ali lupljenjem.
English: H. pylori together with gastric acid are major factors in the development of peptic ulcer disease.
Slovenian: H. pylori in želodčna kislina sta med glavnimi dejavniki za pojav peptične ulkusne bolezni.
English: Perforated unit dose blister (hospital pack):
Slovenian: Perforirani pretisni omot za enkratni odmerek (bolnišnično pakiranje):
English: The usual dose is one 20 mg tablet or two 10 mg tablets once a day for 14 days.
Slovenian: Običajen odmerek je ena 20-mg tableta ali dve 10-mg tableti enkrat na dan 14 dni.
English: Blood and lymphatic system disorders Rare:
Slovenian: Bolezni krvi in limfatičnega sistema Redki:
English: Concomitant administration of omeprazole (40 mg once daily) and atazanavir 300 mg/ritonavir 100 mg to healthy volunteers resulted in a 75% decrease of the atazanavir exposure.
Slovenian: Uporaba omeprazola (40 mg enkrat na dan) in 300 mg atazanavirja/100 mg ritonavirja je pri zdravih prostovoljcih zmanjšala izpostavljenost atazanavirju za 75 %.
English: • Sudden wheezing, swelling of your lips, tongue and throat or body, rash, fainting or difficulties to swallow (severe allergic reaction).
Slovenian: • Nenadno piskajoče dihanje, oteklost ustnic, jezika in žrela ali telesa, izpuščaj, omedlevico ali težave s požiranjem (huda alergijska reakcija).
English: 10 mg once daily.
Slovenian: 40 mg enkrat na dan.
English: Since omeprazole is metabolised by CYP2C19 and CYP3A4, active substances known to inhibit CYP2C19 or CYP3A4 (such as clarithromycin and voriconazole) may lead to increased omeprazole serum levels by decreasing omeprazole's rate of metabolism.
Slovenian: Omeprazol se presnovi s CYP2C19 in CYP3A4, zato lahko učinkovine, ki zavirajo CYP2C19 ali CYP3A4 (npr. klaritromicin in vorikonazol), povečajo koncentracijo omeprazola v serumu, ker zmanjšajo hitrost njegove presnove.
English: Almost 80% of a dose of omeprazole is excreted as metabolites in the urine, the remainder in the faeces, primarily originating from bile secretion.
Slovenian: Skoraj 80 % odmerka omeprazola se izloči v obliki presnovkov v urinu, preostanek pa v blatu; vsebnost v blatu izvira predvsem iz izločanja v žolču.
English: 30 capsules
Slovenian: 30 kapsul
English: Nelfinavir, atazanavir The plasma levels of nelfinavir and atazanavir are decreased in case of co-administration with omeprazole.
Slovenian: Nelfinavir, atazanavir Med uporabo hkrati z omeprazolom se koncentracija nelfinavirja in atazanavirja v plazmi zmanjša.
English: Treatment with proton pump inhibitors may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter (see section 5.1).
Slovenian: Zdravljenje z zaviralci protonske črpalke lahko nekoliko poveča tveganje za okužbe prebavil, npr. z bakterijami Salmonella in Campylobacter(glejte poglavje 5.1).
English: Like all medicines, Losec can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo Losec neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: When dose exceed Losec 80 mg daily, the dose should be divided and given twice daily.
Slovenian: Če odmerek preseže 80 mg zdravila Losec na dan, ga je treba razdeliti in ga uporabljati dvakrat na dan.
English: Losec capsules contain 10 mg, 20 mg or 40 mg of omeprazole.
Slovenian: Kapsule Losec vsebujejo 10 mg, 20 mg ali 40 mg omeprazola.
English: There is limited information available on the effects of overdoses of omeprazole in humans.
Slovenian: O učinkih prevelikega odmerjanja omeprazola pri človeku je malo informacij.
English: • Losec 20 mg + clarithromycin 500 mg + amoxicillin 1,000 mg, each twice daily for one week, or
Slovenian: • Losec 20 mg + klaritromicin 500 mg + amoksicilin 1.000 mg, vsi dvakrat na dan en teden, ali
English: What Losec looks like and contents of the pack
Slovenian: Izgled zdravila Losec in vsebina pakiranja
English: Omeprazole has not shown any tendency to accumulate with once daily dosing.
Slovenian: Omeprazol med uporabo enkrat na dan ni pokazal težnje h kopičenju.
English: 28 x 1 tablets
Slovenian: 28 x 1 tableta
English: • Muscle weakness.
Slovenian: • šibkost mišic
English: Almost 80% of an oral dose of omeprazole is excreted as metabolites in the urine, the remainder in the faeces, primarily originating from bile secretion.
Slovenian: Skoraj 80 % peroralnega odmerka omeprazola se izloči v obliki presnovkov v urinu, preostanek pa v blatu; vsebnost v blatu izvira predvsem iz izločanja v žolču.
English: - The other ingredients are disodium edetate and sodium hydroxide.
Slovenian: - Pomožni snovi sta natrijev edetat in natrijev hidroksid.
English: Losec is to be administered in an intravenous infusion for 20-30 minutes.
Slovenian: Zdravilo Losec je treba dati v intravenski infuziji, ki traja od 20 do 30 minut.
English: The recommended dose is 20 mg once daily for 14 days.
Slovenian: Priporočeni odmerek je 20 mg enkrat na dan 14 dni.
English: To treat symptoms of GERD such as heartburn and acid regurgitation:
Slovenian: Za zdravljenje simptomov GERB, npr. zgage in vračanja kisline:
English: Treatment with acid-reducing drugs may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter.
Slovenian: Zdravljenje z zdravili za zmanjševanje kisline lahko nekoliko poveča tveganje za okužbe prebavil, npr. z bakterijami Salmonella in Campylobacter.
English: For storage conditions of the reconstituted medicinal product, see section 6.3.
Slovenian: Za pogoje shranjevanja pripravljenega (rekonstituiranega) zdravila glejte poglavje 6.3. 6.5 Vrsta ovojnine in vsebina
English: • Treatment of symptomatic gastro-esophageal reflux disease
Slovenian: • zdravljenje simptomatske gastroezofagealne refluksne bolezni
English: • You have jaundice or severe liver disease.
Slovenian: • Če imate zlatenico ali hudo bolezen jeter.
English: Abdominal pain, constipation, diarrhoea, flatulence, nausea/vomiting
Slovenian: bolečine v trebuhu, zaprtost, driska, flatulenca, navzea/bruhanje
English: 35 capsules (10 mg only) 50 capsules (10 mg and 20 mg only) 56 capsules (10 mg only) 60 capsules (20 mg only) 84 capsules (10 mg and 20 mg only)
Slovenian: 35 kapsul (samo 10 mg) 50 kapsul (samo 10 mg in 20 mg) 56 kapsul (samo 10 mg) 60 kapsul (samo 20 mg) 84 kapsul (samo 10 mg in 20 mg)
English: 40 mg: Each gastro-resistant tablet contains 39-41 mg sucrose.
Slovenian: 40 mg: ena gastrorezistentna tableta vsebuje 39-41 mg saharoze.
English: No metabolite has been found to have any effect on gastric acid secretion.
Slovenian: Kot je ugotovljeno, noben presnovek ne vpliva na izločanje želodčne kisline.
English: Losec powder and solvent for solution for injection can be used as an alternative to oral therapy.
Slovenian: Zdravilo Losec prašek in vehikel za raztopino za injiciranje je mogoče uporabiti kot alternativo peroralnemu zdravljenju.
English: Losec gastro-resistant tablets are indicated for the treatment of reflux symptoms (e.g. heartburn, acid regurgitation) in adults
Slovenian: Gastrorezistentne tablete Losec so indicirane za zdravljenje simptomov refluksa (npr. zgage, regurgitacije kisline) pri odraslih.
English: The recommended initial dose is Losec 60 mg daily.
Slovenian: Priporočeni začetni odmerek je 60 mg zdravila Losec na dan.
English: • Dizziness, tingling feelings such as “pins and needles”, feeling sleepy.
Slovenian: • omotica, ščemeči občutki, npr. "mravljinčenje", zaspanost.
English: Oral dosing with omeprazole 20 mg maintains an intragastric pH of ≥ 3 for a mean time of 17 hours of the 24-hour period in duodenal ulcer patients.
Slovenian: Peroralna uporaba 20 mg omeprazola pri bolnikih z razjedo na dvanajstniku ohrani želodčni pH ≥ 3 povprečno 17 ur 24-urnega obdobja.
English: The posology recommendations are as follows:
Slovenian: Priporočila za odmerjanje so:
English: Carton for bottle and label: Keep the container tightly closed in order to protect from moisture.
Slovenian: Škatla za plastenko in nalepko: Vsebnik shranjujte tesno zaprt za zagotovitev zaščite pred vlago.
English: • Store this blister in the original package in order to protect from moisture.
Slovenian: • Shranjujte ta pretisni omot v originalnem pakiranju za zagotovitev zaščite pred vlago.
English: • Hypomagnesaemia
Slovenian: • hipomagneziemija
English: 14 capsules
Slovenian: 14 kapsul
English: [See Annex I - To be completed nationally] Omeprazole
Slovenian: [Glejte Dodatek I - izpolni država članica] omeprazol
English: During long-term treatment gastric glandular cysts have been reported in a somewhat increased frequency.
Slovenian: Med dolgotrajnim zdravljenjem je bilo opisano nekoliko pogostejše pojavljanje želodčnih glandularnih cist.
English: 50 x 1 tablets
Slovenian: 50 x 1 tableta
English: Dermatitis, pruritus, rash, urticaria
Slovenian: dermatitis, srbenje, izpuščaj, urtikarija
English: WHAT LOSEC IS AND WHAT IT IS USED FOR Losec contains the active substance omeprazole.
Slovenian: KAJ JE ZDRAVILO LOSEC IN ZA KAJ GA UPORABLJAMO Zdravilo Losec vsebuje zdravilno učinkovino omeprazol.
English: If symptom control has not been achieved after four weeks treatment with Losec 20 mg daily, further investigation is recommended.
Slovenian: Če simptomi po štirih tednih zdravljenja z 20 mg zdravila Losec na dan niso obvladani, so potrebne nadaljnje preiskave.
English: Taking Losec with food and drink You can take your tablets with food or on an empty stomach.
Slovenian: Jemanje zdravila Losec skupaj s hrano in pijačo Tablete lahko vzamete s hrano ali na prazen želodec.
English: Taking Losec with food and drink You can take your capsules with food or on an empty stomach.
Slovenian: Jemanje zdravila Losec skupaj s hrano in pijačo Kapsule lahko vzamete s hrano ali na prazen želodec.
English: If symptom control has not been achieved after 4 weeks treatment with Losec 20 mg daily, further investigation is recommended.
Slovenian: Če simptomi po 4 tednih zdravljenja z 20 mg zdravila Losec na dan niso obvladani, so potrebne nadaljnje preiskave.
English: • Too much acid in the stomach caused by a growth in the pancreas (Zollinger-Ellison syndrome).
Slovenian: • Čezmernega izločanja želodčne kisline, ki je posledica rašče v trebušni slinavki (Zollinger-Ellisonovega sindroma).
English: If you take more Losec than you should If you take more Losec than prescribed by your doctor, talk to your doctor or pharmacist straight away.
Slovenian: Če ste vzeli večji odmerek zdravila Losec, kot bi smeli Če ste vzeli več zdravila Losec, kot vam ga je predpisal zdravnik, se takoj posvetujte z zdravnikom ali farmacevtom.
English: In a crossover clinical study, clopidogrel (300 mg loading dose followed by 75 mg/day) alone and with omeprazole (80 mg at the same time as clopidogrel) were administered for 5 days.
Slovenian: V navzkrižni klinični študiji so 5 dni uporabljali bodisi klopidogrel sam(polnilni odmerek 300 mg in potem 75 mg/dan) bodisi z omeprazolom (80 mg hkrati s klopidogrelom).
English: Concomitant administration of omeprazole with nelfinavir is contraindicated (see section 4.3).
Slovenian: Uporaba omeprazola hkrati z nelfinavirjem je kontraindicirana (glejte poglavje 4.3).
English: Nausea, vomiting, dizziness, abdominal pain, diarrhoea and headache have been reported.
Slovenian: Opisane so bile navzea, bruhanje, omotica, bolečine v trebuhu, driska in glavobol.
English: • If you or your child have trouble swallowing the capsules: - Open the capsules and swallow the contents directly with half a glass of water or put the contents into a glass of still (non-fizzy) water, any acidic fruit juice (e.g. apple, orange or pineapple) or apple sauce.
Slovenian: • Če vi ali vaš otrok težko pogoltneta kapsule: - Odprite kapsule in njihovo vsebino neposredno zaužijte s pol kozarca vode, ali pa njihovo vsebino dajte v kozarec navadne vode (brez mehurčkov), katerikoli kisel sadni sok (npr. jabolčni, pomarančni ali ananasov) ali v čežano.
English: Powder for injection: sodium hydroxide (for pH adjustment).
Slovenian: - Pomožne snovi so: Prašek za injekcijo: natrijev hidroksid (za prilagoditev pH).
English: This may be associated with a high fever and joint pains (Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis)
Slovenian: To je lahko povezano z zelo visoko telesno temperaturo in bolečinami v sklepih (multiformni eritem, Stevens-Johnsonov sindrom,
English: Pharmacotherapeutic group: Proton pump inhibitors, ATC code: A02BC01
Slovenian: Oznaka ATC: A02BC01
English: If you take more Losec than you should If you take more Losec than recommended, talk to your doctor or pharmacist straight away.
Slovenian: Če ste vzeli večji odmerek zdravila Losec, kot bi smeli Če ste vzeli več zdravila Losec, kot je priporočeno, se takoj posvetujte z zdravnikom ali farmacevtom.
English: Losec powder for solution for infusion can be used as an alternative to oral therapy.
Slovenian: Zdravilo Losec prašek za raztopino za infundiranje je mogoče uporabiti kot alternativo peroralnemu zdravljenju.
English: Losec gastro-resistant tablets contain sucrose.
Slovenian: Gastrorezistentne tablete Losec vsebujejo saharozo.
English: The exposure to the active metabolite of clopidogrel was decreased by 46% (Day 1) and 42% (Day 5) when clopidogrel and omeprazole were administered together.
Slovenian: Če sta bila klopidogrel in omeprazol uporabljena skupaj, se je izpostavljenost aktivnemu presnovku klopidogrela zmanjšala za 46 % (1. dan) oz. 42 % (5. dan).
English: Omeprazole is a moderate inhibitor of CYP2C19, the major omeprazole metabolising enzyme.
Slovenian: Omeprazol je zmeren zaviralec CYP2C19, ki je glavni encim za presnovo omeprazola.