FrancophonIA/ELRC3.0 huggingface dataset:
English: Predictability of sustained virological response - Naïve patients: Virological response by week 12 is defined as at least 2-log viral load decrease or undetectable levels of HCV-RNA.Virological response by week 4 is defined as at least 1-log viral load decrease or undetectable levels of HCV-RNA.
Croatian: Predvidljivost trajnog virološkog odgovora - bolesnici koji prethodno nisu bili liječeni: Virološki odgovor do 12. tjedna definira se kao smanjenje količine virusa za najmanje 2 log ili kao nemjerljiva HCV-RNK.
English: Excipients with known effect: Each vial contains 40 mg of sucrose per 0.5 ml.
Croatian: Pomoćne tvari s poznatim učinkom Jedna bočica sadrži 40 mg saharoze u 0,5 ml.
English: Dose to be administered
Croatian: Doza koju treba primijeniti
English: Please refer to the ribavirin and boceprevir Summary of Product Characteristics (SmPCs) when ViraferonPeg is to be used in combination with these medicines.
Croatian: Molimo pročitajte Sažetak opisa svojstava lijeka za ribavirin i boceprevir ako će se ViraferonPeg primjenjivati u kombinaciji s tim lijekovima.
English: Carton 50 micrograms
Croatian: Kutija 50 mikrograma
English: Hold the syringe with the needle in the vial pointing up.
Croatian: Držite štrcaljku tako da je igla u bočici okrenuta prema gore.
English: How to use ViraferonPeg
Croatian: Kako primjenjivati ViraferonPeg
English: Carton 100 micrograms
Croatian: Kutija 100 mikrograma
English: First dose reduction to ViraferonPeg 1 µg/kg
Croatian: Prvo smanjenje doze lijeka ViraferonPeg na 1 μg/kg
English: Rare side effects (may affect up to 1 in 1,000 people): - diabetic ketoacidosis (medical emergency due to build-up of ketone bodies in the blood as a result of out-of-control diabetes), - seizures (convulsions) and bipolar disorders (mood disorders characterized by alternating episodes of sadness and excitement), - eye problems including changes in vision, damage to the retina, obstruction of the retinal artery, inflammation of the optic nerve, swelling of the eye, - congestive heart failure, abnormal heart rhythm, pericarditis (inflammation of the lining of the heart), inflammation and degeneration of muscle tissue and peripheral nerves, kidney problems, - sarcoidosis (a disease characterized by persistent fever, weight loss, joint pain and swelling, skin lesions and swollen glands).
Croatian: Rijetke nuspojave (mogu se javiti u do 1 na 1000 osoba): - dijabetička ketoacidoza (hitno stanje zbog nakupljanja ketonskih tijela u krvi kao posljedica nekontrolirane šećerne bolesti), - napadaji (konvulzije) i bipolarni poremećaji (poremećaji raspoloženja obilježeni naizmjeničnim epizodama tuge i uzbuđenja), - problemi s očima koji obuhvaćaju promjene vida, oštećenje mrežnice, opstrukciju mrežnične arterije, upalu očnog živca, oticanje oka, - kongestivno zatajenje srca, poremećaj srčanog ritma, perikarditis (upala srčane ovojnice), upala i degeneracija mišićnog tkiva i perifernih živaca, tegobe s bubrezima, - sarkoidoza (bolest koju prate stalna vrućica, gubitak tjelesne težine, bol i oticanje zglobova, oštećenja kože i otečene žlijezde).
English: Discontinuation of ViraferonPeg should be considered in patients who develop new or worsening ophthalmological disorders.
Croatian: U bolesnika u kojih se razviju novi ili pogoršaju postojeći oftalmološki poremećaji treba razmotriti obustavu lijeka ViraferonPeg.
English: How to store ViraferonPeg
Croatian: Kako čuvati ViraferonPeg
English: Your healthcare provider will instruct you how to self-inject this medicine.
Croatian: Vaš zdravstveni radnik će Vas uputiti kako da si sami date injekciju lijeka ViraferonPeg.
English: Table 2b Two-step dose reduction of ViraferonPeg in combination therapy in adults First dose reduction to ViraferonPeg 1 µg/kg
Croatian: Tablica 2b Smanjenje doze lijeka ViraferonPeg u dva koraka u kombiniranoj terapiji u odraslih
English: 3 mcg/kg/week (2 weeks)
Croatian: 3 µg/kg na tjedan (2 tjedna)
English: Detailed instructions for subcutaneous administration are provided at the end of this leaflet (see section “How to self-inject ViraferonPeg”).
Croatian: Detaljne upute za potkožnu primjenu se nalaze na kraju ove upute (vidjeti dio
English: This medicine, when given alone, is usually given at a dose of 0.5 or 1.0 microgram per kilogram of body weight once a week, for 6 months to 1 year.
Croatian: Primjena u odraslih - liječenje samo lijekom ViraferonPeg Kad se primjenjuje samostalno, ovaj lijek se obično daje u dozi od 0,5 ili 1,0 mikrograma po kilogramu tjelesne težine jedanput na tjedan, tijekom 6 mjeseci do godinu dana.
English: Paediatric population (bitherapy only) - Dose to be administered Dosing for children 3 years of age and older and adolescent patients is determined by body surface area for ViraferonPeg and by body weight for ribavirin.
Croatian: Za djecu u dobi od 3 i više godina i adolescente doziranje lijeka ViraferonPeg se određuje prema tjelesnoj površini, a ribavirina prema tjelesnoj težini.
English: For weight, pre-treatment to end of long-term follow-up, weightfor-age percentiles decreased 1.3 and 5.5 percentiles among subjects treated for 24 weeks or 48 weeks, respectively.
Croatian: Kada je u pitanju tjelesna težina, od razdoblja prije početka liječenja do završetka dugotrajnog praćenja percentili na percentilnoj krivulji težine za dob smanjili su se za 1,3 percentila u djece liječene 24 tjedna te za 5,5 percentila u djece liječene 48 tjedana.
English: • Neutrophil count
Croatian: • neutrofili
English: Please refer to the ribavirin SmPC when ViraferonPeg is to be used in combination with ribavirin.
Croatian: Molimo pročitajte Sažetak opisa svojstava lijeka za ribavirin ako će se ViraferonPeg primjenjivati u kombinaciji s ribavirinom.
English: Powder and solvent for solution for injection in pre-filled pen.
Croatian: Prašak i otapalo za otopinu za injekciju u napunjenoj brizgalici.
English: Dapsone (N-acetyltransferase substrate)
Croatian: N-acetiltransferaze)
English: The solution should be clear and colourless before use.
Croatian: Otopina prije primjene mora biti bistra i bezbojna.
English: Patients were randomized to receive either ViraferonPeg (1.5 µg/kg/week) plus ribavirin (800 mg/day) or interferon alfa-2b (3 MIU TIW) plus ribavirin (800 mg/day) for 48 weeks with a follow-up period of 6 months.
Croatian: Bolesnici su bili randomizirani u skupine koje su primale ViraferonPeg (1,5 μg/kg na tjedan) i ribavirin (800 mg na dan) ili interferon alfa-2b (3 mil.
English: Liver enzymes and hepatic function should be closely monitored in cirrhotic patients.
Croatian: U bolesnika s cirozom moraju se pomno nadzirati jetreni enzimi i funkcija jetre.
English: Hypothyroidism
Croatian: hipotireoza
English: You may dial up or down to any dose prior to injection.
Croatian: Prije injekcije vijak za doziranje možete okretati u bilo kojem smjeru do bilo koje doze.
English: Use in adults - ViraferonPeg alone
Croatian: Primjena u odraslih - ViraferonPeg u kombiniranom liječenju
English: Conjunctival haemorrhage, eye pruritus, keratitis, vision blurred, photophobia Ear and labyrinth disorders
Croatian: krvarenje konjunktive, svrbež oka, keratitis, zamagljen vid, fotofobija Poremećaji uha i labirinta
English: Reminder: Please read the “Pregnancy and breast-feeding” section of the Package Leaflet for ribavirin before using it in combination with this medicine.
Croatian: Podsjetnik: molimo pročitajte dio "Trudnoća i dojenje" u uputi o lijeku za ribavirin prije nego što ga uzmete u kombinaciji s ovim lijekom.
English: In a clinical trial, approximately 1.2 % of patients treated with ViraferonPeg or interferon alfa-2b in combination with ribavirin reported life-threatening psychiatric events during treatment.
Croatian: U jednom su kliničkom ispitivanju prijavljeni po život opasni psihijatrijski događaji u približno 1,2% bolesnika liječenih lijekom ViraferonPeg ili interferonom alfa-2b u kombinaciji s ribavirinom.
English: From pre-treatment to end of long-term followup among subjects treated for 24 or 48 weeks, height-for-age percentiles decreased 1.3 and 9.0 percentiles, respectively.
Croatian: Od razdoblja prije početka liječenja do završetka dugotrajnog praćenja, percentil visine za dob smanjio se za 1,3 percentila u djece liječene 24 tjedna odnosno za 9,0 percentila u djece liječene 48 tjedana.
English: Reminder: Please read the “Warnings and precautions” section of the Package Leaflet for ribavirin before using it in combination with this medicine.
Croatian: Podsjetnik: Molimo pročitajte i dio "Upozorenja i mjere opreza" u uputi o lijeku za ribavirin prije nego što ga uzmete u kombinaciji s ovim lijekom.
English: Common side effects (may affect up to 1 in 10 people): - fungal infection, common cold, cold sores, pharyngitis (sore throat), sinusitis, ear infection, coughing, throat pain, feeling cold, eye pain, - decrease in blood clotting cells called platelets, that may result in easy bruising and spontaneous bleeding, swollen glands (swollen lymph nodes), blood thyroid tests abnormalities, decrease in thyroid gland activity, which may make you feel tired, depressed, increase your sensitivity to cold and other symptoms,
Croatian: Česte nuspojave (mogu se javiti u do 1 na 10 osoba): - gljivična infekcija, obična prehlada, herpetični mjehurići, faringitis (upala grla), upala sinusa, infekcija uha, kašalj, grlobolja, osjećaj hladnoće, bol u oku, - smanjenje broja stanica koje zgrušavaju krv, a zovu se trombociti, što može dovesti do laganog nastajanja modrica i spontanog krvarenja, otečene žlijezde (otečeni limfni čvorovi), poremećaji nalaza krvnih pretraga funkcije štitnjače, smanjena aktivnost štitnjače, zbog čega se možete osjećati umorno, depresivno, biti osjetljiviji na hladnoću i imati druge simptome,
English: Diarrhoea, aphthous stomatitis, cheilosis, mouth ulceration, stomach discomfort, oral pain
Croatian: proljev, aftozni stomatitis, heilitis, ulceracije u ustima, nelagoda u želucu, bol u ustima
English: Two trials have been conducted in patients co-infected with HIV and HCV.
Croatian: Bolesnici s istodobnom infekcijom HCV-om i HIV-om Dva su ispitivanja provedena u bolesnika s istodobnom infekcijom HCV-om i HIV-om.
English: More significant obtundation and coma, including cases of encephalopathy, have been observed in some patients, usually elderly, treated at higher doses for oncology indications.
Croatian: U nekih bolesnika, obično starijih, liječenih visokim dozama zbog onkoloških bolesti primijećeni su značajnije promijenjeno stanje svijesti i koma, uključujući slučajeve encefalopatije.
English: Volume of ViraferonPeg to administer (ml)
Croatian: Volumen lijeka ViraferonPeg koji treba primijeniti (ml)
English: Desipramine (CYP2D6 substrate)
Croatian: Dezipramin (supstrat CYP2D6)
English: Discontinue ViraferonPeg if:
Croatian: Obustaviti liječenje lijekom ViraferonPeg ako su:
English: ViraferonPeg is available in different pack sizes: - 1 vial of powder for solution for injection and 1 ampoule of solvent for injection; - 1 vial of powder for solution for injection, 1 ampoule of solvent for injection, 1 injection syringe,
Croatian: ViraferonPeg je dostupan u pakiranjima koja sadrže: - 1 bočicu s praškom za otopinu za injekciju i 1 ampulu s otapalom za parenteralnu primjenu; - 1 bočicu s praškom za otopinu za injekciju, 1 ampulu s otapalom za parenteralnu primjenu,
English: Careful co-administration of thioridazine with the product (ViraferonPeg) is recommended.
Croatian: Preporučuje se oprez kod istodobne primjene tioridazina s ovim lijekom (ViraferonPeg).
English: Injection site erythema, fatigue, pyrexia, rigors, influenza-like illness, asthenia, pain, malaise, irritability
Croatian: eritem na mjestu injiciranja, umor, pireksija, zimica, bolest nalik gripi, astenija, bol, malaksalost, razdražljivost
English: 2 injection needles and 1 cleansing swab; - 4 vials of powder for solution for injection and 4 ampoules of solvent for injection; - 4 vials of powder for solution for injection, 4 ampoules of solvent for injection, 4 injection syringes,
Croatian: 1 štrcaljku za injekciju, 2 igle za injekciju i 1 tupfer za čišćenje; - 4 bočice s praškom za otopinu za injekciju i 4 ampule s otapalom za parenteralnu primjenu; - 4 bočice s praškom za otopinu za injekciju, 4 ampule s otapalom za parenteralnu primjenu,
English: Headache, dizziness
Croatian: glavobolja, omaglica
English: Very common side effects (may affect more than 1 in 10 people): - feeling depressed, irritability, trouble falling asleep or staying asleep, feeling anxious or nervous, difficulty concentrating, mood swings, - headache, dizziness, tired feeling, shaking chills, fever, flu-like symptoms, virus infection, weakness, - difficult breathing, pharyngitis (sore throat), coughing, - stomach pain, vomiting, nausea, diarrhoea, loss of appetite, loss of weight, dry mouth, - hair loss, itching, dry skin, rash, irritation or redness (and rarely, skin damage) at the site of injection, - decreases in the number of red blood cells (that may cause fatigue, shortness of breath, dizziness), decrease in certain white blood cells (that makes you more susceptible to different infections),
Croatian: Vrlo česte nuspojave (mogu se javiti u više od 1 na 10 osoba): - depresivnost, razdražljivost, poteškoće s uspavljivanjem ili održavanjem sna, tjeskoba ili nervoza, poteškoće s koncentracijom, promjene raspoloženja, - glavobolja, omaglica, osjećaj umora, zimica s tresavicom, vrućica, simptomi nalik gripi, virusna infekcija, slabost, - otežano disanje, faringitis (upala grla), kašalj, - bol u trbuhu, povraćanje, mučnina, proljev, gubitak teka, gubitak tjelesne težine, suha usta, - gubitak kose, svrbež, suha koža, osip, iritacija ili crvenilo (i rijetko, oštećenje kože) na mjestu injekcije, - smanjenje broja crvenih krvnih stanica (to može uzrokovati umor, nedostatak zraka, omaglicu),
English: A small volume is lost during preparation of ViraferonPeg for injection when the dose is measured and injected.
Croatian: Tijekom pripreme lijeka ViraferonPeg za injekciju, pri mjerenju doze i davanju injekcije, izgubi se mali dio volumena.
English: 1.5 mcg/kg/week (4 weeks)
Croatian: 1,5 µg/kg na tjedan (4 tjedna)
English: - are taking telbivudine.
Croatian: Za potkožnu primjenu.
English: - are being treated for a mental illness or had treatment in the past for any other nervous or mental disorder, including depression (such as feelings of sadness, dejection) or suicidal or homicidal behaviour (see section 4 “Possible side effects”).
Croatian: - ako se liječite od psihičke bolesti ili ste se u prošlosti liječili od bilo kojeg drugog neurološkog ili psihičkog poremećaja, uključujući depresiju (poput osjećaja tuge, malodušnosti) ili ponašanje koje upućuje na moguće samoubojstvo ili ubojstvo (vidjeti dio 4. "Moguće nuspojave") - ikada imali srčani udar ili srčane tegobe, - ako imate bolest bubrega, liječnik Vam može propisati nižu dozu od uobičajene te će redovito tijekom liječenja pratiti vrijednosti parametara bubrežne funkcije u krvi.
English: Especially in patients on a high dose of methadone, the risk for QTc prolongation should be considered.
Croatian: Treba uzeti u obzir rizik od produljenja QTc-intervala, osobito u bolesnika koji uzimaju visoke doze metadona.
English: • Platelets
Croatian: • trombociti
English: Do not use if it is discoloured or if particles are present.
Croatian: Ne smijete je upotrijebiti ako je promijenila boju ili su u njoj prisutne čestice.
English: Slovenská republika Merck Sharp & Dohme, s. r. o. Tel: +421 2 58282010 dpoc_czechslovak@merck.com
Croatian: Česká republika Merck Sharp & Dohme s.r.o. Tel: +420 233 010 111 dpoc_czechslovak @merck.com
English: ViraferonPeg strength (g/0.5 ml)
Croatian: Jačina lijeka ViraferonPeg (µg/0,5 ml)
English: No pharmacokinetic interactions were noted between ViraferonPeg and ribavirin in a multiple-dose pharmacokinetic study.
Croatian: U ispitivanju farmakokinetike višekratnih doza nisu zabilježene farmakokinetičke interakcije između lijeka ViraferonPeg i ribavirina.
English: When patients are administered ViraferonPeg with medications metabolized by CYP1A2 or CYP2D6, the extent of the decrease in cytochrome P 450 activity is unlikely to have a clinical impact, except with medicines which have a narrow therapeutic margin (Table 5).
Croatian: Kada se ViraferonPeg bolesnicima primjenjuje s lijekovima koji se metaboliziraju posredstvom CYP1A2 ili CYP2D6, razmjer smanjenja aktivnosti citokroma
English: 2 cleansing swabs; - 4 pre-filled pens containing powder and solvent for solution for injection, 4 needles ("Push-On Needle"),
Croatian: 2 tupfera za čišćenje - 4 napunjene brizgalice koje sadrže prašak i otapalo za otopinu za injekciju 4 igle (potisna igla)
English: Refer to the SmPC for boceprevir.
Croatian: Pročitajte Sažetak opisa svojstava lijeka za boceprevir.
English: For BMI, pre-treatment to end of long-term follow-up, BMI-for-age percentiles decreased 1.8 and 7.5 percentiles among subjects treated for 24 weeks or 48 weeks, respectively.
Croatian: Kada je u pitanju indeks tjelesne mase (engl. body mass index, BMI), od razdoblja prije početka liječenja do završetka dugotrajnog praćenja percentili na percentilnoj krivulji indeksa tjelesne mase za dob smanjili su se za 1,8 percentila u djece liječene 24 tjedna te za 7,5 percentila u djece liječene 48 tjedana.
English: Therefore, each pre-filled pen contains an excess amount of solvent and ViraferonPeg powder to ensure delivery of the labelled dose in 0.5 ml of ViraferonPeg, solution for injection.
Croatian: Zato svaka napunjena brizgalica sadrži nešto veću količinu otapala i ViraferonPeg praška kako bi se osigurala primjena deklarirane doze u 0,5 ml ViraferonPeg otopine za injekciju.
English: 8 injection needles and 4 cleansing swabs; - 6 vials of powder for solution for injection and 6 ampoules of solvent for injection; - 12 vials of powder for solution for injection, 12 ampoules of solvent for injection, 12 injection syringes, 24 injection needles and 12 cleansing swabs.
Croatian: 4 štrcaljke za injekciju, 8 igala za injekciju i 4 tupfera za čišćenje; - 6 bočica s praškom za otopinu za injekciju i 6 ampula s otapalom za parenteralnu primjenu; - 12 bočica s praškom za otopinu za injekciju, 12 ampula s otapalom za parenteralnu primjenu,
English: Powder: disodium phosphate; anhydrous, sodium dihydrogen phosphate dihydrate; sucrose and polysorbate 80.
Croatian: Prašak: natrijev hidrogenfosfat, bezvodni; natrijev dihidrogenfosfat dihidrat, saharoza i polisorbat 80.
English: Consideration should be given to replacing zidovudine in a combination anti-retroviral treatment (ART) regimen if this is already established.
Croatian: Ako je već uspostavljen režim kombinirane antiretrovirusne terapije, treba razmotriti zamjenu zidovudina drugim lijekom.
English: - 12 vials of powder for solution for injection, 12 ampoules of solvent for parenteral use, 12 injection syringes, 24 injection needles and 12 cleansing swabs.
Croatian: 12 štrcaljki za injekciju, 24 igle za injekciju i 12 tupfera za čišćenje.
English: Standard haematologic tests, blood chemistry and a test of thyroid function must be conducted in all patients prior to initiating therapy.
Croatian: U svih se bolesnika prije početka liječenja moraju provesti standardne hematološke i biokemijske pretrage kao i ispitivanje funkcije štitnjače.
English: Device body
Croatian: Primatelji presatka organa
English: A positive predictive value of 50 % (52/104; Study 1) was observed for HCV/HIV co-infected patients receiving bitherapy.
Croatian: Za bolesnike s istodobnom infekcijom HCV-om i HIV-om koji su primali dvojnu terapiju zabilježena je pozitivna prediktivna vrijednost od 50% (52/104; Ispitivanje 1).
English: *, injection site inflammation, fatigue, asthenia, irritability, chills, pyrexia, influenza like illness, pain
Croatian: reakcija na mjestu injiciranja*, upala na mjestu injiciranja, umor, astenija, razdražljivost, zimica, pireksija, bolest nalik gripi, bol
English: ViraferonPeg 1.5 micrograms/kg
Croatian: ViraferonPeg 1,5 mikrograma/kg
English: Ear pain
Croatian: bol u uhu
English: You should use a different place each time you give yourself an injection.
Croatian: Lijek trebate injicirati svaki puta na drugo mjesto.
English: 8 cleansing swabs; - 12 pre-filled pens containing powder and solvent for solution for injection, 12 needles ("Push-On Needle"),
Croatian: 8 tupfera za čišćenje - 12 napunjenih brizgalica koje sadrže prašak i otapalo za otopinu za injekciju 12 igala (potisna igla)
English: Therefore, each vial contains an extra amount of solvent and ViraferonPeg powder to ensure delivery of the labeled dose in 0.5 ml of ViraferonPeg, solution for injection.
Croatian: Stoga svaka bočica sadrži dodatnu količinu otapala i ViraferonPeg praška kako bi se osigurala primjena deklarirane doze u 0,5 ml ViraferonPeg otopine za injekciju.
English: 120 micrograms/0.5 ml
Croatian: 120 mikrograma/0,5 ml
English: nd dose reduction of ViraferonPeg is to 0.5 µg/kg/week.
Croatian: Ako je potrebno, drugo smanjenje doze lijeka ViraferonPeg je na 0,5 μg/kg na tjedan.
English: 150 micrograms/0.5 ml
Croatian: 150 mikrograma/0,5 ml
English: Monotherapy with ViraferonPeg and bitherapy with ViraferonPeg and ribavirin Naïve patients
Croatian: Monoterapija lijekom ViraferonPeg i dvojna terapija lijekom ViraferonPeg i ribavirinom Bolesnici koji prethodno nisu bili liječeni
English: - pain in joints and muscles, muscle and bone pain.
Croatian: bol u kostima, mišićna slabost
English: ViraferonPeg 120 micrograms powder and solvent for solution for injection EU/1/00/132/016
Croatian: ViraferonPeg 120 mikrograma prašak i otapalo za otopinu za injekciju EU/1/00/132/016
English: 80 micrograms/0.5 ml
Croatian: 80 mikrograma/0,5 ml
English: 8 cleansing swabs; - 12 pre-filled pens (CLEARCLICK) containing powder and solvent for solution for injection, 12 needles ("Push-On Needle"),
Croatian: 8 tupfera za čišćenje - 12 napunjenih brizgalica (CLEARCLICK) s praškom i otapalom za otopinu za injekciju 12 igala (potisna igla)
English: Vasculitis
Croatian: vaskulitis
English: 100 micrograms/0.5 ml
Croatian: 100 mikrograma/0,5 ml
English: NR
Croatian: B.
English: Uncommon side effects (may affect up to 1 in 100 people): - painful or difficult urination, urinary frequency, the presence of excess protein in the urine, painful menstruation, - itchy anal area (pinworms or ascarids), inflammation of the lining membrane of the stomach and the intestines, inflamed gums, enlarged liver, - abnormal behaviour, emotional disorder, fear, nightmare, tremor, decreased sensitivity to touch, numbness or tingling feeling, pain radiating along the course of one or more nerves, drowsiness, - bleeding of the mucous membrane that lines the inner surface of the eyelids, itchy eyes, eye pain, blurred vision, intolerance to light, - low blood pressure, paleness, nasal discomfort, runny nose, wheezing, difficult breathing, chest pain or discomfort, - redness, swelling, pain of skin, shingles, skin sensitive to sunlight, rash with raised spotted lesions, skin discolouration, peeling of skin, shortening of muscle tissue, muscle twitching, facial pain, bruising.
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na 100 osoba): - bolno ili otežano mokrenje, učestalo mokrenje, prekomjerna količina bjelančevina u mokraći, bolna mjesečnica, - svrbež analnog područja (dječje gliste ili askaridi), upala želučane i crijevne sluznice, upala desni, povećana jetra, - neuobičajeno ponašanje, emocionalni poremećaj, strah, noćne more, nevoljno drhtanje, smanjena osjetljivost na dodir, utrnulost ili trnci, bol koja sijeva uzduž jednog ili više živaca, omamljenost, - krvarenje iz sluznice koja oblaže unutarnju površinu kapaka, svrbež očiju, bol u oku, zamagljen vid, nepodnošenje svjetla, - snižen krvni tlak, bljedilo, osjećaj nelagode u nosu, curenje nosa, piskanje pri disanju, otežano disanje, bol ili nelagoda u prsima, - crvenilo, oticanje, bol kože, herpes zoster, osjetljivost kože na sunčevu svjetlost, osip s točkastim uzdignućima, promjena boje kože, ljuštenje kože, skraćenje mišićnog tkiva, trzanje mišića, bol u licu, stvaranje modrica.
English: 1 mcg/kg/week (4 weeks)
Croatian: 1 µg/kg na tjedan (4 tjedna)