FrancophonIA/ELRC3.0 huggingface dataset:
English: The CVMP agreed that although there is limited data for M. synoviae in comparison with M. gallisepticum, the available information from the studies provided is sufficient to support the conclusion that Denagard 45% at a dose of 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight for three to five consecutive days would be efficacious in the treatment and metaphylaxis of Airsacculitis and Infectious Synovitis caused by M. synoviae.
Croatian: CVMP se složio da, iako su podaci za M. synoviae ograničeni u usporedbi s onima za M. gallisepticum, dostupne informacije dobivene u ispitivanjima dovoljne su za potvrdu zaključka da bi Denagard 45 % u dozi od 25 mg tiamulin hidrogenfumarata (ekvivalent 55,6 mg VMP-a)/kg tjelesne težine primjenjivan tijekom tri do pet uzastopnih dana bio djelotvoran za liječenje i metafilaksu aerosakulitisa i infektivnog sinovitisa prouzročenih bakterijom M. synoviae.
English: Dose-related reductions in mortality, average lung lesion area and A. pleuropneumoniae re-isolation but no complete clinical cure were observed at lower doses (20 mg).
Croatian: Pri nižim dozama (20 mg) opažena su s dozom povezana smanjenja u smrtnosti, prosječnoj površini lezije pluća i ponovnoj izolaciji uzročnika A. pleuropneumoniae, ali bez potpunog kliničkog izlječenja.
English: Granules for use in drinking water
Croatian: Granule za uporabu u vodi za piće
English: If signs of an interaction do occur, stop both the administration of tiamulin-medicated drinking water and also the administration of ionophore-contaminated feed immediately.
Croatian: Ako primijetite znakove interakcije, odmah prekinite primjenu vode za piće s tiamulinom i hrane kontaminirane ionoforima.
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals: Personal protective equipment consisting of safety glasses or goggles and gloves should be worn when handling the veterinary medicinal product in order to avoid contamination of the user's eyes and topical exposure of skin.
Croatian: Kod rukovanja veterinarsko-medicinskim proizvodom treba nositi osobnu zaštitnu opremu koja se sastoji od zaštitnih naočala i rukavica, kako bi se spriječilo da proizvod dospije u oči ili na kožu.
English: Serum protein-binding was approximately 45%.
Croatian: Vezivanje serumskih bjelančevina približno je 45 %.
English: including infections complicated by Pasteurella multocida susceptible to tiamulin.
Croatian: uključujući infekcije komplicirane bakterijom Pasteurella multocida osjetljivom na tiamulin.
English: The LD5 is 1090 mg/kg body weight for chickens and 840 mg/kg body weight for turkeys.
Croatian: LD5 je 1090 mg/kg t.m., za kokoši te 840 mg/kg t.m. za pure.
English: Colon contents concentrations of tiamulin have been estimated at 3.41 µg/ml following administration of tiamulin hydrogen fumarate at 8.8 mg/kg body weight.
Croatian: Koncentracija tiamulina u kolonu procjenjuje se na 3,41 µg/ml nakon primjene 8,8 mg/kg t.m.
English: The indication for treatment and metaphylaxis of Enzootic Pneumonia caused by M. hyopneumoniae, including infections complicated by P. multocida was supported by in vitro susceptibility data from the European MycoPath I project, proprietary clinical studies and literature.
Croatian: Indikacija za liječenje i metafilaksu enzootske pneumonije prouzročene bakterijom M. hyopneumoniae , uključujući infekcije koje su komplicirane zbog bakterije P. multocida potkrijepljena je in vitro podacima osjetljivosti dobivenim u europskom projektu MycoPath I, vlasničkim kliničkim ispitivanjima i iz literature.
English: and Gebhart, C.J. (2009) In vitro antimicrobial activity against 10 North American and European Lawsonia intracellularis isolates.
Croatian: 5 Wattanaphansak, S., Singer, R.S. and Gebhart, C.J. (2009) In vitro antimicrobial activity against 10 North American and European Lawsonia intracellularis isolates.
English: - Treatment and metaphylaxis of Enzootic Pneumonia caused by Mycoplasma hyopneumoniae,
Croatian: - Liječenje i metafilaksa enzootske pneumonije koju uzrokuje Mycoplasma hyopneumoniae,
English: Tiamulin was administered for three days by gavage at 20-30 mg tiamulin hydrogen fumarate/kg body weight or in the drinking water.
Croatian: Tiamulin je davan intubacijom u dozi 20 - 30 mg tiamulin hidrogenfumarata/kg tjelesne težine ili u vodi za piće.
English: If an interaction does occur, stop tiamulin medication immediately and replace with fresh drinking water.
Croatian: Ako dođe do interakcije, odmah prekinite primjenu tiamulina i vodu s tiamulinom zamijenite svježom vodom za piće.
English: In the field trials tiamulin was administered at inclusion rates of 125 - 250 ppm or daily doses from 12.7 to 59.7 mg tiamulin hydrogen fumarate/kg body weight for three days.
Croatian: U ispitivanjima na terenu tiamulin je primjenjivan pri stopi prisutnosti od 125 do 250 ppm ili dnevnim dozama od 12,7 do 59,7 mg tiamulin hidrogenfumarata/kg tjelesne težine tijekom tri dana.
English: Denagard 45% has also been shown to be efficacious for the treatment of Enzootic Pneumonia caused by M. hyopneumoniae including infections complicated by Pasteurella multocida.
Croatian: Denagard 45 % pokazao se djelotvornim i za liječenje i metafilaksu enzootske pneumonije prouzročene bakterijom M. hyopneumoniae, uključujući infekcije komplicirane bakterijom Pasteurella multocida.
English: In the older European data there was a wider range of MICs for M. gallisepticum (<0.004 and >256 µg/ml) with a MIC50 of 0,008 µg/ml and a MIC90 of 1 µg/ml.
Croatian: U starijim europskim podacima raspon MIK-ova bio je širi za M. gallisepticum (<0,004 i >256 µg/ml) s MIK50 od 0,008 µg/ml i MIK90 od 1 µg/ml.
English: Serum protein-binding was approximately 50%.
Croatian: Vezivanje serumskih bjelančevina približno je 50 %.
English: For chickens and turkeys, in order to avoid interactions between the incompatible ionophores monensin, narasin and salinomycin and tiamulin, the feed mill supplying the birds feed should be notified that tiamulin will be used and that these anticoccidials should not be included in the feed or contaminate the feed.
Croatian: Kako biste izbjegli interakcije između nekompatibilnih ionofora monenzina, narazina i salinomicina te tiamulina kod kokoši i pura, tvornicu koja dostavlja hranu za perad potrebno je obavijestiti da namjeravate primijeniti tiamulin i da hrana ne smije sadržavati kokcidiostatike, odnosno da hrana njima ne smije biti kontaminirana.
English: The indication Pleuropneumonia caused by A. pleuropneumoniae was supported by in vitro susceptibility data and by artificial infection studies.
Croatian: Indikacija pleuropneumonije prouzročene bakterijom A. pleuropneumoniae potkrijepljena je podacima osjetljivosti in vitro te ispitivanjima u kojima je infekcija izazvana umjetno.
English: • Enzootic Pneumonia caused by M hyopneumoniae, including infections complicated by Pasteurella multocida, or Pleuropneumonia caused by A. pleuropneumoniae: 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight administered daily for 5 consecutive days.
Croatian: M hyopneumoniae , uključujući infekcije komplicirane zbog bakterije Pasteurella multocida ili pleuropneumonije prouzročene bakterijom A. pleuropneumoniae: 20 mg tiamulin hidrogenfumarata (što odgovara 44,4 mg VMP-a) / kg tjelesne težine primjenjivanog dnevno tijekom 5 uzastopnih dana.
English: Belgium VMD nv Hoge Mauw 900
Croatian: VMD nv
English: Denagard 45% and its associated names are veterinary medicinal products presented as granules for use in drinking water for pigs, chicken and turkeys containing 450 mg tiamulin hydrogen fumarate as an active substance per gram product.
Croatian: Denagard 45 % i povezani nazivi jesu veterinarsko-medicinski proizvodi u obliku granula za primjenu u vodi za piće za svinje, piliće i purane koji sadrže 450 mg tiamulin hidrogenfumarata kao djelatnu tvar po gramu VMP-a.
English: Following a 50 mg tiamulin hydrogen fumarate/kg body weight single dose the Cmax was 4.02 µg/ml in serum by microbiological assay and after a 25 mg/kg dose it was 1.86 µg/ml.
Croatian: Nakon primjene jednokratne doze od 50 mg tiamulinfumarata/kg t.m., Cmax bila je 4,02 µg/ml u serumu, utvrđeno mikrobiološkom metodom, a nakon 25 mg/kg bila je 1,86 µg/ml.
English: voor varkens en kippen
Croatian: Svinje, kokoši
English: Clinical efficacy in the treatment of Porcine Proliferative Enteropathy (ileitis) caused by L. intracellularis was demonstrated in three artificial infection studies and one field trial.
Croatian: Klinička djelotvornost u liječenju proliferativne enteropatije (ileitis) svinja prouzročene bakterijom L. intracellularis dokazana je u trima ispitivanjima umjetno izazvane zaraze i jednom ispitivanju na terenu.
English: The indication Porcine Colonic Spirochaetosis (colitis) caused by B. pilosicoli was supported by in vitro susceptibility data and field studies.
Croatian: Indikacija crijevne spirohetoze (kolitis) svinja prouzročene bakterijom B. pilosicoli potkrijepljena je podacima za osjetljivost in vitro i ispitivanjima na terenu.
English: Special storage precautions
Croatian: Posebne mjere pri čuvanju
English: In the field trials tiamulin was administered at inclusion rates of 125 - 250 ppm and estimated doses from 13.3 - 32.5 mg tiamulin hydrogen fumarate/kg body weight for three days.
Croatian: U ispitivanjima provedenim na terenu tiamulin je primjenjivan pri stopi prisutnosti 125 - 250 ppm i procijenjenim dozama 13,3 - 32,5 mg tiamulin hidrogenfumarata/kg tjelesne težine tijekom tri dana.
English: Denagard 45% is a veterinary medicinal product presented as granules for use in drinking water for pigs, chicken and turkeys containing 450 mg tiamulin hydrogen fumarate per gram product.
Croatian: Denagard 45% je veterinarsko-medicinski proizvod u obliku granula za primjenu u vodi za piće za svinje, piliće i purane koji sadrže 450 mg tiamulin hidrogenfumarata po gramu VMP-a.
English: Laying birds: Can be used in laying chickens and in breeding chickens and turkeys.
Croatian: Nesilice: Može se primijeniti kod nesilica, rasplodnih kokoši i pura.
English: For meat and offal from turkey, a GLP-compliant residue depletion study was provided.
Croatian: Za meso i iznutrice purana provedeno je ispitivanje deplecije rezidua u skladu s dobrom laboratorijskom praksom.
English: ATC vet code: QJ 01 XQ 01
Croatian: Farmakoterapijska grupa: antibakterijski pripravak za sustavne infekcije/pleuromutilini/tiamulin ATCvet kod: QJ 01 XQ 01
English: Clinical efficacy in the treatment of swine dysentery caused by B. hyodysenteriae was demonstrated in two artificial infection studies and in a series of six field trials.
Croatian: Klinička djelotvornost u liječenju dizenterije svinja prouzročene bakterijom B. hyodysenteriae dokazana je u dvama ispitivanjima u kojima je zaraza izazvana umjetno te u nizu od šest ispitivanja na terenu.
English: The presence of the disease in the herd must be established before the product is used.
Croatian: Prije primjene proizvoda mora se ustanoviti prisutnost bolesti u uzgoju.
English: Guidance for preparing product solutions:
Croatian: Smjernice za pripremu otopine:
English: 450 mg/g Oral granules Swine, chickens (broilers, rearing of broilers, layers / breeders), turkeys (for fattening and breeding)
Croatian: Tiamulinfumarat 450 mg/g Oralne granule Svinje, kokoši (brojleri, uzgoj brojlera, nesilice/rasplodne životinje), pure (za tov i rasplod)
English: In European isolates tiamulin was highly active against M. hyopneumoniae, with MIC50 of 0.016 µg/ml, MIC90 of 0.062 µg/ml, and a MIC range of 0.002-0.125 µg/ml (MycoPath I project, 2014).
Croatian: U europskim izolatima tiamulin je bio vrlo aktivan protiv M. hyopneumoniae, s vrijednošću MIK50 od 0,016 µg/ml, MIK90 od 0,062 µg/ml i rasponom vrijednosti MIK-a od 0,002 - 0,125 µg/ml
English: In these studies the MICs ranged from ≤0.008-64 µg/ml, with MIC50s of ≤0.062 µg/ml up to 0.125 µg/ml and MIC90s of 0.25 µg/ml up to 8 µg/ml.
Croatian: U tim ispitivanjima MIK-ovi su bili u rasponu od ≤0,008 - 64 µg/ml, s MIK50s od ≤ 0,062 µg/ml do 0,125 µg/ml i MIK90s od 0,25 µg/ml do 8 µg/ml.
English: • Chronic Respiratory Disease caused by M. gallisepticum and Airsacculitis and Infectious Synovitis caused by M. synoviae: 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight administered daily for the period of 3 to 5 consecutive days.
Croatian: Kronična respiratorna bolest koju uzrokuje bakterija M. gallisepticum i aerosakulitis i infektivni sinovitis koju uzrokuje M. synoviae: 25 mg tiamulin hidrogenfumarata (što odgovara 55,6 mg VMP-a) / kg tjelesne težine primijenjeno dnevno tijekom 3 do 5 uzastopnih dana.
English: Marketing authorisation number(s) To be completed nationally.
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE U PROMET Dopuniti na nacionalnoj razini.
English: Similar findings were reported from other studies dating from 1997 - 2014 with MIC50 ranging from ≤0.015 µg/ml - 0.06 µg/ml, MIC90 ranging from 0.031 µg/ml - 0,125 µg/ml, and MIC ranges of 0.002-0.125 µg/ml.
Croatian: Slični podaci zabilježeni su u drugim ispitivanjima u razdoblju od1997. do 2014., s vrijednostima MIK50 u rasponu od ≤0,015 µg/ml - 0,06 µg/ml, MIK90 u rasponu od 0,031 µg/ml - 0,125 µg/ml i MIK u rasponu od 0,002 - 0,125 µg/ml.
English: On very rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin.
Croatian: Vrlo rijetko, kod svinja se nakon primjene tiamulina može pojaviti crvenilo kože ili blagi edem.
English: Doses administered ranged from 8.8-20 mg tiamulin hydrogen fumarate/kg body weight for 5 days.
Croatian: Primjenjivane doze bile su u rasponu 8,8 - 20 mg tiamulin hidrogenfumarata/kg tjelesne težine tijekom 5 dana.
English: Artificial challenge studies were carried out using tiamulin inclusion rates in drinking water ranging from 120 to 180 ppm equivalent to doses of 20 to 40 mg tiamulin hydrogen fumarate/kg body weight.
Croatian: Ispitivanja s umjetno izazvanom infekcijom provedena su primjenom stope prisutnosti tiamulina u vodi za piće u rasponu od 120 do 180 ppm, što odgovara dozama od 20 do 40 mg tiamulin hidrogenfumarata/kg tjelesne težine.
English: • the CVMP reviewed the summary of product characteristics, labelling and package leaflet proposed by the marketing authorisation holders and considered all the overall submitted data; the CVMP has recommended the amendment of the marketing authorisations for Denagard 45% and its associated names as referred in Annex I for which the summary of product characteristics, labelling and package leaflet are set out in Annex III.
Croatian: CVMP preporučuje izmjenu odobrenja za stavljanje lijeka u promet za Denagard 45 % i povezanih naziva kao što je navedeno u Prilogu I., a za koji su sažetak opisa svojstava, označavanje i uputa o VMP-u navedeni u Prilogu III.
English: In turkeys serum levels of tiamulin hydrogen fumarate are lower with a 50 mg tiamulin hydrogen fumarate/kg body weight single dose giving a Cmax of 3.02 µg/ml in serum, and 25 mg/kg giving 1.46 µg/ml.
Croatian: Kod pura su razine tiamulinfumarata u serumu niže pa jednokratna doza od 50 mg tiamulinfumarata/kg t.m. postiže Cmax od 3,02 µg/ml u serumu, a doza od 25 mg/kg razinu od 1,46 µg/ml.
English: Tiamulin is a bacteriostatic semi-synthetic antibiotic belonging to the pleuromutilin group of antibiotics and acts at the ribosomal level to inhibit bacterial protein synthesis.
Croatian: Tiamulin je bakteriostatski polusintetički antibiotik iz skupine pleuromutilina te djeluje na ribosomskoj razini i koči sintezu bakterijskih bjelančevina.
English: MARKETING AUTHORISATION HOLDER To be completed nationally.
Croatian: NOSITELJ ODOBRENJA ZA STAVLJANJE U PROMET Dopuniti na nacionalnoj razini.
English: • Meat and offal: 6 days
Croatian: Meso i iznutrice: šest dana
English: The feed should be tested for the ionophores prior to use if there is any suspicion that contamination of the feed might occur.
Croatian: Ako postoji sumnja da je došlo do kontaminacije hrane, morate hranu prije uporabe testirati na prisustvo ionofora.
English: From these data the CVMP concluded that Denagard 45% at a dose of 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight for three to five consecutive days would be efficacious in the treatment and metaphylaxis of Infectious Sinusitis and Airsacculitis caused by Mycoplasma gallisepticum, Mycoplasma synoviae and Mycoplasma meleagridis susceptible to tiamulin.
Croatian: Na temelju tih podataka CVMP je zaključio da bi Denagard 45 % u dozi od 40 mg tiamulin hidrogenfumarata (što odgovara 88,9 mg VMP-a) / kg tjelesne težine primjenjivan tijekom tri do pet uzastopnih dana bio djelotvoran za liječenje i metafilaksu infektivnog sinusitisa i aerosakulitisa prouzročenih bakterijama Mycoplasma gallisepticum, Mycoplasma synoviae i Mycoplasma meleagridis osjetljivih na tiamulin.
English: • Infectious Sinusitis and Airsacculitis caused by M. gallisepticum, M. synoviae and M. meleagridis: 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight administered daily for the period of 3 to 5 consecutive days
Croatian: Infektivni sinusitis i aerosakulitis prouzročeni bakterijama M. gallisepticum, M. synoviaei M. meleagridis: 40 mg tiamulin hidrogenfumarata (što odgovara 88,9 mg VMP-a) / kg tjelesne težine primijenjeno dnevno tijekom 3 do 5 uzastopnih dana.
English: For M. synoviae MICs ranged from 0.05 to 0.5 µg/ml with MIC50s of 0.1 µg/ml and a MIC90 of 0.25 µg/ml.
Croatian: Za M. synoviae MIK-ovi su se kretali u rasponu od 0,05 do 0,5 µg/ml s MIK50s od 0,1 µg/ml i MIK90 od 0,25 µg/ml.
English: Target species pigs, indications and posology
Croatian: Svinje kao ciljne vrste životinja, indikacije i doziranje
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Denagard 450 mg/g granules for use in drinking water for pigs, chickens and turkeys
Croatian: NAZIV VETERINARSKO-MEDICINSKOG PROIZVODA Denagard 450 mg/g, granule za uporabu u vodi za piće, za svinje, kokoši i pure
English: Special precautions for the disposal of unused product or waste materials, if any Dispose of waste material in accordance with local requirements.
Croatian: 15. Posebne mjere opreza pri odlaganju neupotrebljenih proizvoda ili otpadnih materijala, ako ih ima
English: • Meat and offal: 2 days
Croatian: Meso i iznutrice: dva dana
English: In drinking water use.
Croatian: U vodi za piće.
English: The artificial infection studies were carried out using tiamulin inclusion rates in drinking water ranging from 60 to 250 ppm or estimated daily doses from 15.4 to 64.2 mg tiamulin hydrogen fumarate/kg body weight.
Croatian: Ispitivanja umjetno izazvane zaraze provedena su primjenom stopa prisutnosti tiamulina u vodi za piće u rasponu od 60 do 250 ppm ili procijenjenim dnevnim dozama od 15,4 do 64,2 mg tiamulin hidrogenfumarata/kg tjelesne težine.
English: • Swine Dysentery caused by B hyodysenteriae or Porcine Colonic Spirochaetosis (colitis) caused by B.pilosicoli: 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight administered daily in the drinking water of pigs for 3 to 5 consecutive days depending on the severity of the infection and/or the duration of the disease.
Croatian: Dizenterija svinja prouzročena bakterijom B hyodysenteriae ili crijevna spirohetoza (kolitis) svinja prouzročena bakterijom B. pilosicoli: 8,8 mg tiamulin hidrogenfumarata (što odgovara 19,6 mg VMP-a/kg tjelesne težine primjenjivanog dnevno na svinjama u vodi za piće tijekom 3 do 5 uzastopnih dana, ovisno o težini infekcije i/ili trajanju bolesti.
English: Pigs, chickens (broilers, pullets, layers and breeders), turkeys (fattening and breeding birds)
Croatian: Svinje, kokoši (brojleri, pilenke, nesilice i rasplodne životinje), pure (za tov i rasplod)
English: For M. synoviae MICs ranged from 0.004 to 0.5 µg/ml with a MIC50 of 0,125 µg/ml and a MIC90 of 0.25 µg/ml.
Croatian: Za M. synoviae MIK-ovi su bili u rasponu od 0,004 do 0,5 µg/ml s MIK50 od 0,125 µg/ml i MIK90 od 0,25 µg/ml.
English: Pigs, chickens, turkeys
Croatian: Svinje, kokoši, pure
English: Lee, J.M.
Croatian: Kim, J.Y.
English: Water intake may be depressed during the administration of tiamulin in birds.
Croatian: Unos vode može biti smanjen tijekom primjene tiamulina kod peradi.
English: ii) For the treatment of Porcine Colonic Spirochaetosis (colitis) caused by Brachyspira pilosicoli.
Croatian: Za liječenje spirohetoze kolona svinja (kolitisa) koju uzrokuje Brachyspira pilosicoli.
English: From these data the CVMP concluded that Denagard 45% at a dose of 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight for three to five consecutive days would be efficacious in the treatment and metaphylaxis of Chronic Respiratory Disease caused by M. gallisepticum.
Croatian: Na temelju tih podataka CVMP je zaključio da bi Denagard 45 % u dozi od 25 mg tiamulin hidrogenfumarata (što odgovara 55,6 mg VMP-a)/kg tjelesne težine primjenjivan tijekom tri do pet uzastopnih dana bio djelotvoran za liječenje i metafilaksu kronične respiratorne bolesti prouzročene bakterijom M. gallisepticum.
English: Name of the veterinary medicinal product Denagard 450 mg/g granules for use in drinking water for pigs, chickens and turkeys Tiamulin hydrogen fumarate
Croatian: Naziv veterinarsko-medicinskog proizvoda Denagard 450 mg/g, granule za uporabu u vodi za piće za svinje, kokoši i pure Tiamulinfumarat
English: From these data the CVMP concluded that Denagard 45% at a dose of 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight for five consecutive days would be efficacious in the treatment and metaphylaxis of Enzootic Pneumonia caused by M. hyopneumoniae, including infections complicated by P. multocida.
Croatian: Na temelju tih podataka CVMP je zaključio da bi Denagard 45 % u dozi od 20 mg tiamulin hidrogenfumarata (što odgovara 44,4 mg VMP-a)/kg tjelesne težine primjenjivan tijekom pet uzastopnih dana bio djelotvoran za liječenje i metafilaksu enzootske pneumonije prouzročene bakterijom M. hyopneumoniae, uključujući infekcije komplicirane zbog P. multocida.
English: The indication treatment of Porcine Proliferative Enteropathy (ileitis) caused by L. intracellularis was supported by in vitro susceptibility data, artificial infection studies and a field trial.
Croatian: Liječenje proliferativne enteropatije (ileitis) svinja prouzročene bakterijom L. intracellularis potkrijepljeno je podacima osjetljivosti iz in vitro, ispitivanja, ispitivanjima umjetno izazvane zaraze te u ispitivanju na terenu.
English: At 250 ppm tiamulin hydrogen fumarate administered for three days significant improvements in clinical endpoints, pathological signs and elimination of M. gallisepticum were shown.
Croatian: primjenjivanog zaraženim svinjama tri do pet dana, pokazala su se značajna poboljšanja u kliničkim ishodima, patološkim znakovima i eliminaciji bakterije B. hyodysenteriae.
English: Shelf life after first opening the immediate packaging: 3 months Shelf life after dilution or reconstitution according to directions: The solution remains stable for 24 hours.
Croatian: Rok valjanosti poslije razrjeđenja ili rekonstitucije prema uputi: otopina je stabilna 24 sata.
English: Animals received a mean dose of 29 mg tiamulin hydrogen fumarate /kg body weight for five days via drinking water; this
Croatian: Životinje su primale prosječnu dozu od 29 mg tiamulin hidrogenfumarata / kg tjelesne težine tijekom pet dana u vodi za piće; ta je doza bila viša od indicirane doze (25 mg tiamulin hidrogenfumarata).
English: Artificial challenge studies were carried out using tiamulin inclusion rates in drinking water ranging from 60 to 250 ppm or estimated doses from 10 to 64.2 mg tiamulin hydrogen fumarate/kg body weight.
Croatian: Ispitivanja s umjetno izazvanom infekcijom provedena su primjenom stope prisutnosti tiamulina u vodi za piće u rasponu od 60 do 250 ppm ili procijenjenim dozama od 10 do 64,2 mg tiamulin hidrogenfumarata/kg tjelesne težine.
English: Turkeys Meat and offal: 6 days
Croatian: Pure Meso i jestive iznutrice: 6 dana
English: 783 Kim, I.S.
Croatian: Kang, J.M. 783 Kim, I.S. Choi, and J.B. Lee.
English: Target species chickens, indications and posology
Croatian: Pilići kao ciljne vrste životinja, indikacije i doziranje