FrancophonIA/ELRC3.0 huggingface dataset:
English: - The other ingredients are microcrystalline cellulose, tartric acid, maize starch, pregelatinized maize starch, talc, stearic acid.
Slovenian: Druge sestavine zdravila so mikrokristalna celuloza, vinska kislina, koruzni škrob, želatiniran koruzni škrob, smukec, stearinska kislina.
English: Rasagiline use in patients with moderate hepatic impairment should be avoided.
Slovenian: Uporabi razagilina pri bolnikih z zmerno jetrno okvaro se je potrebno izogibati.
English: White to off-white, oblong (approximately 11.5 mm x 6 mm) biconvex tablets, debossed with ‘R9SE' on one side and ‘1' on the other side.
Slovenian: Bele do belkaste, podolgovate (približno 11,5 mm x 6 mm) bikonveksne tablete, z vtisnjenim ''R9SE'' na eni strani in ''1'' na drugi strani tablete.
English: Uncommon: angina pectoris (0.5% vs. 0%)
Slovenian: Občasni: angina pektoris (0,5% proti 0%)
English: Rasagiline must not be administered along with other MAO inhibitors (including medicinal and natural products without prescription e.g. St. John's Wort) as there may be a risk of non-selective MAO inhibition that may lead to hypertensive crises (see section 4.3).
Slovenian: Razagilin se ne sme uporabljati sočasno z drugimi inhibitorji MAO (vključno z zdravili in naravnimi pripravki brez recepta, kot je npr. šentjanževka), ker obstaja tveganje, da neselektivna inhibicija monoaminooksidaze (MAO) lahko vodi do hipertenzivnih kriz (glejte poglavje 4.3).
English: Common: hallucinations (2.9% vs. 2.1%), abnormal dreams (2.1% vs. 0.8%) Uncommon: confusion (0.8% vs. 0.5%)
Slovenian: Pogosti: halucinacije (2,9% proti 2,1%), neobičajne sanje (2,1% proti 0,8%) Občasni: zmedenost (0,8% proti 0,5%)
English: Rasagiline use in patients with severe hepatic impairment is contraindicated (see section 4.3).
Slovenian: Uporaba razagilina pri bolnikih s hudo jetrno okvaro je kontraindicirana (glejte poglavje 4.3).
English: What Rasagiline Mylan is and what it is used for 2.
Slovenian: Kaj je zdravilo Razagilin Mylan in za kaj ga uporabljamo 2.
English: Therefore, in view of the MAO inhibitory activity of rasagiline, antidepressants should be administered with caution.
Slovenian: Zaradi tega je s stališča inhibitorne monoaminooksidazne aktivnosti razagilina potrebno antidepresive uporabljati previdno.
English: In study II, patients were randomly assigned to receive placebo (229 patients), or rasagiline 1 mg/day (231 patients) or the catechol-O-methyl transferase (COMT) inhibitor, entacapone, 200 mg taken along with scheduled doses of levodopa (LD)/decarboxylase inhibitor (227 patients), and were treated for 18 weeks.
Slovenian: V študiji II so bolniki naključno prejemali placebo (229 bolnikov) ali razagilin 1 mg/dan (231 bolnikov) ali katehol-o-metil-transferazni inhibitor (COMT), entakapon 200 mg, skupaj s predvidenimi odmerki levodope (LD)/dekarboksilazni inhibitor (227 bolnikov); zdravljeni so bili 18 tednov.
English: Very common: dyskinesia (10.5% vs. 6.2%)
Slovenian: Zelo pogosti: diskinezija (10,5% proti 6,2%)
English: Rasagiline Mylan with food and drink Rasagiline Mylan may be taken with or without food.
Slovenian: Zdravilo Razagilin Mylan skupaj s hrano in pijačo Zdravilo Razagilin Mylan lahko jemljete bodisi s hrano bodisi brez nje.
English: Common: dermatitis (2.0% vs. 0%)
Slovenian: Pogosti: dermatitis (2,0% proti 0%)
English: Experimental data indicated that rasagiline inhibits prolactin secretion and thus, may inhibit lactation.
Slovenian: Eksperimentalni podatki kažejo, da razagilin zavira izločanje prolaktina, to pa lahko zavre dojenje.
English: Preclinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated-dose toxicity and reproduction toxicity.
Slovenian: Predklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih in reproduktivne toksičnosti ne kažejo posebnega tveganja za človeka.
English: Rasagiline was not carcinogenic in rats at systemic exposure, 84-339 times the expected plasma exposures in humans at 1 mg/day.
Slovenian: Razagilin pri sistemski izpostavljenosti pri podganah, ki je bila 84 do 339-kratna pričakovani plazemski izpostavljenosti pri človeku pri 1 mg/dan, ni bil kancerogen.
English: Ask your doctor for advice prior to driving or using machines.
Slovenian: Pred vožnjo ali uporabo strojev se posvetujte s svojim zdravnikom.
English: The list below includes adverse reactions which were reported with a higher incidence in placebo controlled studies, in patients receiving 1 mg/day rasagiline (rasagiline group n=149, placebo group n=151).
Slovenian: Spodnji seznam vključuje neželene učinke, ki so bili z večjo incidenco sporočani v s placebom kontroliranih študijah pri bolnikih, ki so prejemali razagilin 1 mg/dan (skupina razagilina n = 149, skupina placeba n = 151).
English: Do not stop taking Rasagiline Mylan without first talking to your doctor.
Slovenian: Če ste prenehali jemati zdravilo Razagilin Mylan Ne prenehajte jemati zdravila Razagilin Mylan, ne da bi se prej pogovorili z zdravnikom.
English: Do not store above 25ºC.
Slovenian: Shranjujte pri temperaturi do 25 ºC.
English: Common: depression (5.4% vs. 2%), hallucinations (1.3% vs. 0.7%) Nervous system disorders
Slovenian: Pogosti: depresija (5,4% proti 2%), halucinacije (1,3% proti 0,7%) Bolezni živčevja
English: In study III, the mean difference compared to placebo was -0.94h, 95% CI [-1.36, -0.51], p<0.0001.
Slovenian: V študiji III je bila v primerjavi s placebom povprečna razlika -0,94 ur, 95% CI [-1,36, -0,51]; p < 0,0001.
English: What Rasagiline Mylan is and what it is used for
Slovenian: Kaj je zdravilo Razagilin Mylan in za kaj ga uporabljamo
English: There have been reports of medicinal product interactions with the concomitant use of dextromethorphan and non-selective MAO inhibitors.
Slovenian: Obstajajo poročila o interakcijah zdravil pri sočasni uporabi dekstrometorfana in neselektivnih inhibitorjev MAO.
English: Conjugation of rasagiline and its metabolites was also found to be a major elimination pathway to yield glucuronides.
Slovenian: Ugotovljeno je, da je konjugacija razagilina in njegovih presnovkov glavna izločevalna pot nastalih glukuronidov.
English: What Rasagiline Mylan looks like and contents of the pack Rasagiline tablets are presented as white to off-white, oblong (approximately 11.5 mm x 6 mm) biconvex tablets, debossed with ‘R9SE' on one side and ‘1' on the other side.
Slovenian: Izgled zdravila Razagilin Mylan in vsebina pakiranja Tablete razagilina so bele do belkaste, podolgovate (približno 11,5 mm x 6 mm) bikonveksne tablete, z vtisnjenim ''R9SE'' na eni strani in ''1'' na drugi strani tablete.
English: In vitro experiments indicate that both routes of rasagiline metabolism are dependent on cytochrome P450 system, with CYP1A2 being the major iso-enzyme involved in rasagiline metabolism.
Slovenian: In vitro poskusi so pokazali, da sta obe poti presnove razagilina odvisni od citokrom P450 sistema, kjer je v njegovo presnovo zajet CYP1A2 kot glavni izoencim.
English: There were no cases of serotonin syndrome in the rasagiline clinical program in which 115 patients were exposed concomitantly to rasagiline and tricyclics and 141 patients were exposed to rasagiline and SSRIs/ SNRIs.
Slovenian: V kliničnem programu z razagilinom, v katerem je bilo 115 bolnikov izpostavljenih hkrati razagilinu in triciklikom, 141 bolnikov pa je bilo izpostavljenih razagilinu in SSRI/SNRI, ni bilo primerov serotoninskega sindroma.
English: If you are starting treatment with Rasagiline Mylan, you should wait at least 5 weeks after stopping fluoxetine treatment.
Slovenian: Če začenjate zdravljenje z zdravilom Razagilin Mylan, morate po prenehanju zdravljenja s fluoksetinom počakati vsaj 5 tednov.
English: What you need to know before you take Rasagiline Mylan 3.
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Razagilin Mylan 3.
English: Certain antidepressants (selective serotonin reuptake inhibitors, selective serotonin-norepinephrine reuptake inhibitors, tricyclic or tetracyclic antidepressants) the antibiotic ciprofloxacin used against infections the cough suppressant dextromethorphan sympathomimetics such as those present in eye drops, nasal and oral decongestants and cold medicine containing ephedrine or pseudoephedrine
Slovenian: Prosite zdravnika za nasvet, preden začnete hkrati z zdravilom Razagilin Mylan jemati katero od naslednjih zdravil: določeni antidepresivi (selektivni inhibitorji ponovnega privzema serotonina, selektivni inhibitorji ponovnega privzema serotonina-norepinefrina, triciklični ali tetraciklični antidepresivi), antibiotik ciprofloksacin, ki se uporablja proti okužbam, zdravilo za pomirjanje kašlja dekstrometorfan, simpatikomimetiki, kot so tisti, ki so prisotni v kapljicah za oči, nosnih ali peroralnih dekongestivih in zdravila proti prehladu, ki vsebujejo efedrin ali psevdoefedrin.
English: In study III, patients were randomly assigned to receive placebo (159 patients), rasagiline 0.5 mg/day (164 patients), or rasagiline 1 mg/day (149 patients), and were treated for 26 weeks.
Slovenian: V študiji III so bolniki naključno prejemali placebo (159 bolnikov), razagilin 0,5 mg/dan (164 bolnikov) ali razagilin 1 mg/dan (149 bolnikov) ter bili zdravljeni 26 tednov.
English: Rasagiline Mylan
Slovenian: Razagilin Mylan
English: The mean total daily decrease in the OFF time was similar in the entacapone group (-0.80h, 95% CI [-1.20, -0.41], p<0.0001) to that observed in the rasagiline 1 mg group.
Slovenian: Povprečno celotno dnevno skrajšanje OFF časa je bilo v skupini z entakaponom (-0,80 ur, 95% CI [-1,20, -0,41]; p < 0,0001) podobno kot v skupini z razagilinom 1 mg/dan.
English: Common: dystonia (2.4% vs. 0.8%), carpal tunnel syndrome (1.3% vs. 0%), balance disorder (1.6% vs. 0.3%)
Slovenian: Pogosti: distonija (2,4% proti 0,8%), sindrom karpalnega tunela (1,3% proti 0%), motnje ravnotežja (1,6% proti 0,3%)
English: If you are starting treatment with fluoxetine or fluvoxamine, you should wait at least 14 days after stopping Rasagiline Mylan treatment.
Slovenian: Če začenjate zdravljenje s fluoksetinom ali fluvoksaminom, morate po prenehanju zdravljenja z zdravilom Razagilin Mylan počakati vsaj 14 dni.
English: If you take more Rasagiline Mylan than you should If you think that you may have taken too many Rasagiline Mylan tablets, contact your doctor or pharmacist immediately.
Slovenian: Če menite, da ste morda vzeli preveč tablet zdravila Razagilin Mylan, se morate nemudoma posvetovati z zdravnikom ali s farmacevtom.
English: The concomitant use of rasagiline and dextromethorphan or sympathomimetics such as those present in nasal and oral decongestants or cold medicinal product containing ephedrine or pseudoephedrine is not recommended (see section 4.5).
Slovenian: Sočasna uporaba razagilina in dekstrometorfana ali simpatikomimetikov, kot so tisti, ki so prisotni v nazalnih in peroralnih dekongestivih, ali zdravil proti prehladu, ki vsebujejo efedrin ali psevdoefedrin, ni priporočljiva (glejte poglavje 4.5).
English: In mice, increased incidences of combined bronchiolar/alveolar adenoma and/or carcinoma were observed at systemic exposures, 144-213-times the expected plasma exposure in humans at 1 mg/day.
Slovenian: Pri miših so pri sistemski izpostavljenosti, ki je bila 144 do 213-kratna pričakovani plazemski izpostavljenosti pri človeku pri 1 mg/dan, opazovali povečano incidenco kombiniranega bronhiolarnega/alveolarnega adenoma in/ali karcinoma.
English: Synthon Hispania S.L., C/ Castelló no1, Pol. Las Salinas, 08830, Sant Boi de Llobregat, Barcelona, Spain
Slovenian: Las Salinas, 08830, Sant Boi de Llobregat, Barcelona, Španija
English: In study II, the mean difference in the number of hours spent in the “OFF” state compared to placebo was -0.78h, 95% CI [-1.18, -0.39], p=0.0001.
Slovenian: V študiji II je bila povprečna razlika v številu ur, preživetih v »OFF« stanju v primerjavi s placebom0,78 ur, 95% CI [-1,18, -0,39 ], p = 0,0001.
English: In patients taking Rasagiline Mylan and/or other medications used to treat Parkinson's disease, behaviours such as compulsions, obsessive thoughts, addictive gambling, excessive spending, impulsive behaviour and an abnormally high sex drive or an increase in sexual thoughts or feelings have been observed.
Slovenian: Pri bolnikih, ki jemljejo zdravilo Razagilin Mylan in/ali druga zdravila, ki se uporabljajo za zdravljenje Parkinsonove bolezni, so opazili vedenja, kot so kompulzije, obsesivne misli, odvisnost od iger na srečo, prekomerno zapravljanje denarja, impulzivno vedenje in nenormalna povečana spolna sla ali obsedenost s pretiranim predajanjem mislim ali občutkom v povezavi s spolnostjo.
English: Common: influenza (4.7% vs. 0.7%)
Slovenian: Pogosti: gripa (4,7% proti 0,7%)
English: Common: abdominal pain (4.2% vs. 1.3%), constipation (4.2% vs. 2.1%), nausea and vomiting (8.4% vs. 6.2%), dry mouth (3.4% vs. 1.8%)
Slovenian: Pogosti: bolečina v trebuhu (4,2% proti 1,3%), zaprtje (4,2% proti 2,1%), siljenje na bruhanje in bruhanje (8,4% proti 6,2%), suha usta (3,4% proti 1,8%) Bolezni kože in podkožja
English: The tablets are available in blister packs of 7, 10, 28, 30, 100 and 112 tablets and in perforated blister packs containing 7 x 1, 10 x 1, 28 x 1, 30 x 1, 100 x 1 and 112 x 1 tablets.
Slovenian: Tablete so na voljo v pretisnih omotih v škatli po 7, 10, 28, 30, 100 in 112 tablet ali perforiranih enoodmernih pretisnih omotih iz PVC/PVDC/aluminija po 7 x 1, 10 x 1, 28 x 1, 30 x 1, 100 x 1 ali 112 x 1 tableto.
English: Other medicines and Rasagiline Mylan
Slovenian: Druga zdravila in zdravilo Razagilin Mylan
English: Therefore, in view of the MAO inhibitory activity of rasagiline, the concomitant administration of rasagiline and dextromethorphan is not recommended (see section 4.4).
Slovenian: Zaradi inhibitorne monoaminooksidazne aktivnosti razagilina sočasna uporaba razagilina in dekstrometorfana ni priporočljiva (glejte poglavje 4.4).
English: Severe hepatic impairment.
Slovenian: Huda jetrna okvara.
English: The following side effects have been reported in placebo controlled clinical trials:
Slovenian: V kliničnih študijah, nadzorovanimi s placebom, so poročali o naslednjih neželenih učinkih:
English: In the post-marketing period, cases of elevated blood pressure, including rare cases of hypertensive crisis associated with ingestion of unknown amounts of tyramine-rich foods, have been reported in patients taking rasagiline.
Slovenian: V obdobju trženja so pri bolnikih, ki so jemali razagilin, poročali o primerih zvišanega krvnega tlaka, vključno z redkimi primeri hipertenzivne krize, povezanih z zaužitjem neznane količine s tiraminom bogatih jedi.
English: In parentheses is the adverse reaction incidence (% of patients) in rasagiline vs. placebo, respectively.
Slovenian: V oklepaju je incidenca neželenih učinkov (% bolnikov) pri razagilinu v primerjavi s placebom.
English: Rasagiline may be taken with or without food.
Slovenian: Razagilin se lahko jemlje s hrano ali brez nje.
English: Concomitant treatment with other monoamine oxidase (MAO) inhibitors (including medicinal and natural products without prescription e.g. St. John's Wort) or pethidine (see section 4.5).
Slovenian: Sočasno zdravljenje z drugimi inhibitorji monoaminooksidaze (MAO) (vključno z zdravili in naravnimi pripravki brez recepta, kot je npr. šentjanževka) ali s petidinom (glejte poglavje 4.5).
English: At least 14 days should elapse between discontinuation of rasagiline and initiation of treatment with fluoxetine or fluvoxamine.
Slovenian: Najmanj 14 dni pa mora preteči med prekinitvijo zdravljenja z razagilinom in do začetka zdravljenja s fluoksetinom ali fluvoksaminom.
English: Renal impairment No change in dose is required for renal impairment.
Slovenian: Pri ledvičnih okvarah ni potrebno spreminjati odmerka.
English: What you need to know before you take Rasagiline Mylan
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Razagiline Mylan
English: If you forget to take Rasagiline Mylan
Slovenian: Če ste pozabili vzeti zdravilo Razagilin Mylan
English: At least 14 days must elapse between discontinuation of rasagiline and initiation of treatment with MAO inhibitors or pethidine.
Slovenian: Najmanj 14 dni mora preteči med prekinitvijo zdravljenja z razagilinom in začetkom zdravljenja z inhibitorji MAO ali s petidinom.
English: Rasagiline Mylan 1 mg tablets rasagiline
Slovenian: Razagilin Mylan 1 mg tablete razagilin
English: In study I, 404 patients were randomly assigned to receive placebo (138 patients), rasagiline 1 mg/day (134 patients) or rasagiline 2 mg/day (132 patients) and were treated for 26 weeks, there was no active comparator.
Slovenian: V študiji I so bili 404 bolniki naključno razporejeni v skupine in prejemali placebo (138 bolnikov), 1 mg razagilina na dan (134 bolnikov) ali 2 mg razagilina na dan (132 bolnikov); zdravljeni so bili 26 tednov; aktivne primerjave ni bilo.
English: Serious adverse reactions have been reported with the concomitant use of SSRIs, SNRIs, tricyclic/tetracyclic antidepressants and MAO inhibitors.
Slovenian: Poročali so o resnih neželenih učinkih ob sočasni uporabi SSRI, SNRI, tricikličnih in tetracikličnih antidepresivov in inhibitorjev MAO.
English: Uncommon: cerebrovascular accident (0.5% vs. 0.3%) Cardiac disorders
Slovenian: Občasni: možgansko-žilni dogodek (0,5% proti 0,3%) Srčne bolezni
English: The concomitant use of rasagiline and fluoxetine or fluvoxamine should be avoided (see section 4.5).
Slovenian: Sočasni uporabi razagilina in fluoksetina ali fluvoksamina se je potrebno izogibati (glejte poglavje 4.5).
English: The concomitant use of rasagiline and fluoxetine or fluvoxamine should be avoided (see section 4.4).
Slovenian: Sočasni uporabi razagilina in fluoksetina ali fluvoksamina se je potrebno izogibati (glejte poglavje 4.4).
English: In the post-marketing period, cases of serotonin syndrome associated with agitation, confusion, rigidity, pyrexia and myoclonus have been reported by patients treated with antidepressants/SNRI concomitantly with rasagiline.
Slovenian: V obdobju trženja so bolniki, sočasno zdravljeni z antidepresivi/SNRI in razagilinom, navajali primere serotoninskega sindroma, povezanega z agitacijo, zmedenostjo, togostjo, pireksijo in mioklonusom.
English: Common: conjunctivitis (2.7% vs. 0.7%)
Slovenian: Pogosti: konjunktivitis (2,7% proti 0,7%)
English: Therefore, in view of the MAO inhibitory activity of rasagiline, concomitant administration of rasagiline and sympathomimetics such as those present in nasal and oral decongestants or cold medicinal products, containing ephedrine or pseudoephedrine, is not recommended (see section 4.4).
Slovenian: Zaradi inhibitorne monoaminooksidazne aktivnosti razagilina sočasna uporaba razagilina in simpatikomimetikov, kot so tisti, ki so prisotni v nazalnih in peroralnih dekongestivih ali zdravil proti prehladu, ki vključujejo efedrin ali psevdoefedrin, ni priporočljiva (glejte poglavje 4.4).
English: Common: allergy (1.3% vs. 0.7%)
Slovenian: Pogosti: alergija (1,3% proti 0,7%)
English: How to take Rasagiline Mylan 4.
Slovenian: Kako jemati zdravilo Razagilin Mylan 4.
English: Rasagiline Mylan may be taken with or without food.
Slovenian: Zdravilo Razagilin Mylan lahko vzamete s hrano ali brez nje.
English: The concomitant administration of rasagiline and pethidine is contraindicated (see section 4.3).
Slovenian: Sočasna uporaba razagilina in petidina je kontraindicirana (glejte poglavje 4.3).
English: Impulse control disorders (ICDs) can occur in patients treated with dopamine agonists and/or dopaminergic treatments.
Slovenian: Pri bolnikih, ki se zdravijo z agonisti dopamina in/ali dopaminergičnimi zdravljenji, lahko pride do motenj pri obvladovanju impulzov.
English: Neoplasms benign, malignant and unspecified (including cysts and polyps) Uncommon: skin melanoma (0.5% vs. 0.3%)
Slovenian: Benigne, maligne in neopredeljene novotvorbe (vključno s cistami in polipi) Občasni: kožni melanom (0,5% proti 0,3%) Presnovne in prehranske motnje
English: Musculoskeletal and connective tissue disorders Common: arthralgia (2.4% vs. 2.1%), neck pain (1.3% vs. 0.5%)
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva Pogosti: bolečina v sklepih (2,4% proti 2,1%), bolečina v vratu (1,3% proti 0,5%) Preiskave
English: In case patients progress from mild to moderate hepatic impairment rasagiline should be stopped (see section 4.4).
Slovenian: V primeru, da pri bolniku blaga jetrna okvara napreduje do zmerne, se mora zdravljenje z razagilinom prekiniti (glejte poglavje 4.4).
English: Rasagiline Mylan 1 mg tablets
Slovenian: IME ZDRAVILA Razagilin Mylan 1 mg tablete
English: • Rare (may affect up to 1 in 1,000 people)
Slovenian: Redki (pojavijo se lahko pri največ 1 od 1.000 bolnikov)
English: • Very rare (may affect up to 1 in 10,000 people)
Slovenian: Zelo redki (pojavijo se lahko pri največ 1 od 10.000 bolnikov)
English: Caution should be used when initiating treatment with rasagiline in patients with mild hepatic impairment.
Slovenian: Ob začetku zdravljenja z razagilinom pri bolnikih z blago jetrno okvaro je potrebna previdnost.
English: How to store Rasagiline Mylan 6.
Slovenian: Shranjevanje zdravila Razagilin Mylan 6.
English: Common: orthostatic hypotension (3.9% vs. 0.8%) Gastrointestinal disorders
Slovenian: Pogosti: ortostatična hipotenzija (3,9% proti 0,8%)
English: With MAO inhibitors there have been reports of medicinal product interactions with the concomitant use of sympathomimetic medicinal products.
Slovenian: Ob sočasni uporabi inhibitorjev MAO in simpatikomimetičnih zdravil so poročali o medsebojnih interakcijah.
English: Common: decreased appetite (2.4% vs. 0.8%)
Slovenian: Občasni: manjši tek (2,4% proti 0,8%)
English: Decreasing the dose of levodopa may ameliorate this side effect.
Slovenian: Ta neželeni učinek se lahko izboljša z zmanjšanjem odmerka levodope.
English: Do not take the following medicines while taking Rasagaline Mylan: - monoamine oxidase (MAO) inhibitors (e.g. for treatment of depression or Parkinson's disease,
Slovenian: Medtem ko jemljete zdravilo Razagiline Mylan, ne jemljite naslednjih zdravil: zaviralce monoaminooksidaze (MAO) (npr. za zdravljenje depresije ali Parkinsonove bolezni ali pa za katero koli drugo indikacijo), vključno z zdravili in naravnimi pripravki brez recepta, kot je npr. šentjanževka, petidin (močno sredstvo proti bolečinam).
English: In case patients progress from mild to moderate hepatic impairment, rasagiline should be stopped (see section
Slovenian: V primeru, da pri bolniku blaga jetrna okvara napreduje do zmerne, se mora zdravljenje z razagilinom prekiniti (glejte poglavje 5.2).
English: Musculoskeletal and connective tissue disorders Common: musculoskeletal pain (6.7% vs. 2.6%), neck pain (2.7% vs. 0%), arthritis (1.3% vs.0.7%) Renal and urinary disorders
Slovenian: Pogosti: mišično-skeletna bolečina (6,7% proti 2,6%), bolečina v vratu (2,7% proti 0%), artritis
English: Serious adverse reactions have been reported with the concomitant use of pethidine and MAO inhibitors including another selective MAO-B inhibitor.
Slovenian: Ob sočasni uporabi petidina in inhibitorjev MAO, vključno z drugimi selektivnimi inhibitorji MAO-B, so poročali o resnih neželenih učinkih.
English: Warnings and precautions Talk to your doctor before taking Rasagiline Mylan.
Slovenian: Opozorila in previdnostni ukrepi Pred začetkom jemanja zdravila Razagiline Mylan se posvetujte z zdravnikom: če imate blage do zmerne težave z jetri, če imate kakršne koli sumljive kožne spremembe.
English: If you get any side effects, talk to your doctor or pharmacist.
Slovenian: Če opazite kateri koli neželeni učinek , se posvetujte z zdravnikom ali s farmacevtom.
English: • heart attack (myocardial infarction)
Slovenian: Občasni kap (možgansko žilni dogodek) srčni napad (miokardni infarkt) mehurjasti izpuščaj (vezikulobulozni izpuščaj)
English: Rasagiline undergoes almost complete biotransformation in the liver prior to excretion.
Slovenian: Preden se izloči, se razagilin skoraj popolnoma presnovi v jetrih.