FrancophonIA/ELRC3.0 huggingface dataset:
English: The following conventional classification is used: very common (1/10), common (1/100 to <1/10), uncommon (1/1,000 to <1/100), rare (1/10,000 to <1/1,000), very rare (<1/10,000), not known (cannot be estimated from the available data).
Croatian: Za to se koristila sljedeća uobičajena klasifikacija: vrlo često (1/10), često (1/100 i <1/10), manje često (1/1000 i <1/100), rijetko (1/10 000 i <1/1000), vrlo rijetko (<1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: After opening the bottle, the product should be used immediately in order to avoid microbial contamination.
Croatian: Nakon otvaranja boce, lijek treba upotrijebiti odmah kako bi se izbjegla mikrobiološka kontaminacija.
English: Vomiting, nausea
Croatian: Povraćanje, mučnina
English: Hypersensitivity reactions.
Croatian: Reakcije preosjetljivosti.
English: • Hypersensitivity to the active substance, to other bisphosphonates or to any of the excipients listed in section 6.1.
Croatian: • Preosjetljivost na djelatnu tvar, druge bisfosfonate ili neku od pomoćnih tvari navedenih u dijelu 6.1
English: The primary endpoint of the study was the percent change from baseline in lumbar spine bone mineral density (BMD) after 12 months of treatment.
Croatian: Primarni ishod ispitivanja bio je postotak promjene mineralne gustoće kostiju (engl. bone mineral density - BMD) lumbalne kralježnice u odnosu na početne vrijednosti nakon 12 mjeseci liječenja.
English: Your doctor may recommend a dental examination before you start treatment with Zometa.
Croatian: Vaš liječnik može preporučiti pregled kod zubara prije nego počnete liječenje Zometom.
English: The highest non-lethal single intravenous dose was 10 mg/kg bodyweight in mice and 0.6 mg/kg in rats.
Croatian: Najviša jednokratna intravenska doza bez letalnog učinka iznosila je 10 mg/kg tjelesne težine u miševa i 0,6 mg/kg u štakora.
English: Multi-packs containing 4 (4x 1) or 5 (5x 1) bottles.
Croatian: Višestruka pakiranja sadrže 4 (4x 1) ili 5 (5x 1) boca.
English: Thus these results precluded determining a definitive effect of zoledronic acid on fertility in humans.
Croatian: Stoga se na temelju ovih rezultata ne može utvrditi konačan učinak zoledronatne kiseline na plodnost u ljudi.
English: - Aclasta (a medicine that also contains zoledronic acid and is used to treat osteoporosis and other non-cancer diseases of the bone), or any other bisphosphonate, since the combined effects of these medicines taken together with Zometa are unknown.
Croatian: - Aclastu (lijek koji također sadrži zoledronatnu kiselinu i koriste se za liječenje osteoporoze i drugih bolesti kostiju koje nisu uzrokovane rakom) ili bilo koji drugi bisfosfonat, budući da kombinirani učinci ovih lijekova kad se uzimaju zajedno sa Zometom nisu poznati.
English: - Cancer, co-morbid conditions (e.g. anaemia, coagulopathies, infection), smoking.
Croatian: - Rak, komorbiditetna stanja (npr. anemija, koagulopatije, infekcija), pušenje.
English: Dizziness, paraesthesia, dysgeusia, hypoaesthesia, hyperaesthesia, tremor, somnolence
Croatian: Omaglica, parestezija, disgeuzija, hipoestezija, hiperestezija, tremor, somnolencija
English: It is especially important that you tell your doctor if you are also taking: - Aminoglycosides (medicines used to treat severe infections), calcitonin (a type of medicine used to treat post-menopausal osteoporosis and hypercalcaemia), loop diuretics (a type of medicine to treat high blood pressure or oedema) or other calcium-lowering medicines, since the combination of these with bisphosphonates may cause the calcium level in the blood to become too low.
Croatian: Osobito je važno da obavijestite liječnika ako također uzimate: - Aminoglikozide (lijekovi za liječenje teških infekcija), kalcitonin (vrsta lijeka za liječenje postmenopauzalne osteoporoze i hiperkalcemije), diuretici Henleove petlje (vrsta lijekova za liječenje visokog krvnog tlaka ili edema) ili drugi lijekovi koji snizuju razinu kalcija, budući da kombinacija ovih lijekova s bisfosfonatima može dovesti do preniskih razina kalcija u krvi.
English: The onset time is ≤ 3 days post-Zometa infusion, and the reaction is also referred to using the terms “flu-like” or “post-dose” symptoms.
Croatian: Vrijeme nastupa je ≤3 dana nakon infuzije Zomete, a reakcija se još zove “sindrom nalik gripi” ili simptomi “nakon doziranja”.
English: Zoledronic acid shows no appreciable binding to plasma proteins and does not inhibit human P450 enzymes in vitro (see section 5.2), but no formal clinical interaction studies have been performed.
Croatian: Zoledronatna kiselina se ne veže u nekoj zamjetnoj mjeri za proteine plazme i ne inhibira ljudske enzime P450 in vitro (vidjeti dio 5.2), ali nisu provedena službena klinička ispitivanja interakcija.
English: Untreated hypercalcaemia patients generally have some degree of renal function impairment, therefore careful renal function monitoring should be considered.
Croatian: Bolesnici s neliječenom hiperkalcemijom najčešće imaju neki stupanj oštećenja funkcije bubrega pa je stoga potrebno razmotriti pažljivo praćenje funkcije bubrega.
English: Tumours can accelerate normal bone change in such a way that the release of calcium from bone is increased.
Croatian: Tumori mogu ubrzati normalnu pregradnju kosti, zbog čega se kalcij pojačano otpušta iz kostiju.
English: Date of first authorisation: 20.03.2001 Date of latest renewal: 20.03.2006
Croatian: Datum posljednje obnove odobrenja: 20.03.2006.
English: Zoledronic acid belongs to the class of bisphosphonates and acts primarily on bone.
Croatian: Zoledronatna kiselina pripada skupini bisfosfonata i djeluje prvenstveno na kost.
English: In paediatric patients with severe osteogenesis imperfecta, zoledronic acid seems to be associated with more pronounced risks for acute phase reaction, hypocalcaemia and unexplained tachycardia, in comparison to pamidronate, but this difference declined after subsequent infusions.
Croatian: Čini se da je u pedijatrijskih bolesnika s teškim oblikom osteogenesis imperfecta zoledronatna kiselina povezana s izraženijim rizikom od reakcije akutne faze, hipokalcemije i neobjašnjene tahikardije u odnosu na pamidronat, ali ta se razlika smanjila s daljnjim infuzijama.
English: The plasma protein binding is low, with the unbound fraction ranging from 60% at 2 ng/ml to 77% at 2000 ng/ml of zoledronic acid.
Croatian: Vezanje za proteine plazme je nisko, s nevezanom frakcijom u rasponu od 60% kod 2 ng/ml do 77% kod 2000 ng/ml zoledronatne kiseline.
English: From the bone tissue it is released very slowly back into the systemic circulation and eliminated via the kidney.
Croatian: Iz koštanog tkiva se otpušta vrlo sporo natrag u sustavni krvotok i eliminira putem bubrega.
English: The active substance in Zometa is zoledronic acid, which belongs to a group of substances called bisphosphonates.
Croatian: Djelatna tvar u Zometi je zoledronatna kiselina, koja pripada skupini tvari koje se zovu bisfosfonati.
English: Severe kidney impairment (will normally be determined by your doctor with certain specific blood tests).
Croatian: Teško oštećenje funkcije bubrega (obično će ga utvrditi liječnik pomoću određenih specifičnih krvnih pretraga).
English: The majority of the reports refer to cancer patients following tooth extractions or other dental surgeries.
Croatian: Većina zabilježenih slučajeva odnosila se na onkološke bolesnike nakon vađenja zuba ili drugih stomatoloških operacija.
English: No pharmacokinetic data for zoledronic acid are available in patients with hypercalcaemia or in patients with hepatic insufficiency.
Croatian: Nema dostupnih farmakokinetičkih podataka za zoledronatnu kiselinu u bolesnika s hiperkalcemijom ili bolesnika s insuficijencijom jetre.
English: Median time to onset of the first SRE was not reached in the zoledronic acid-treated arm at the end of the study and was significantly prolonged compared to placebo (p=0.007).
Croatian: Medijan vremena do nastupa prvog koštanog događaja nije dosegnut u skupini liječenoj zoledronatnom kiselinom do kraja ispitivanja i bilo je značajno dulje u usporedbi s placebom (p=0,007).
English: Use immediately after reconstitution and dilution.
Croatian: Primijeniti odmah nakon rekonstitucije i razrjeđivanja.
English: In multiple myeloma patients, the risk of renal dysfunction may be increased when Zometa is used in combination with thalidomide.
Croatian: U bolesnika s multiplim mijelomom, rizik od poremećaja funkcije bubrega može biti povećan kad se Zometa koristi u kombinaciji s talidomidom.
English: Dystocia was observed at the lowest dose (0.01 mg/kg bodyweight) tested in the rat.
Croatian: Distocija je bila opažena pri najnižoj dozi (0,01 mg/kg tjelesne težine) ispitanoj u štakora.
English: Following initiation of therapy, serum creatinine should be measured prior to each dose of Zometa and treatment should be withheld if renal function has deteriorated.
Croatian: Nakon početka liječenja kreatinin u serumu treba mjeriti prije primjene svake doze Zomete, a liječenje treba obustaviti ako se funkcija bubrega pogorša.
English: Zometa treatment should be resumed at the same dose as that given prior to treatment interruption.
Croatian: Liječenje Zometom treba nastaviti istom dozom koja se davala prije prekida liječenja.
English: Angioneurotic oedema
Croatian: Angioneurotski edem
English: Patients should also be administered an oral calcium supplement of 500 mg and 400 IU vitamin D daily.
Croatian: Bolesnicima također treba davati peroralni dodatak kalcija od 500 mg i 400 IU vitamina
English: Talk to your doctor before you are given Zometa: if you have or have had a kidney problem.
Croatian: Obratite se svom liječniku prije nego primite Zometu: ako imate ili ste imali tegobe s bubrezima.
English: * Includes vertebral and non-vertebral fractures ** Accounts for all skeletal events, the total number as well as time to each event during the trial NR Not Reached
Croatian: * Uključuje prijelome kralježaka i drugih kostiju ** Odnosi se na sve koštane događaje, njihov ukupni broj i vrijeme do svakog pojedinog događaja tijekom ispitivanja
English: Zoledronic acid was evaluated in rats for potential adverse effects on fertility of the parental and F1 generation.
Croatian: Mogući štetni učinci zoledronatne kiseline na plodnost ispitani su na roditeljskoj i F1 generaciji štakora.
English: Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, pain or swelling, or non-healing of sores or discharge, as these could be signs of a condition called osteonecrosis of the jaw.
Croatian: Odmah se obratite se svom liječniku i zubaru ako imate bilo koji problem s Vašim ustima ili zubima kao što su klimavi zubi, bol ili oticanje, ili ranice koje ne cijele ili iscjedak, jer to mogu biti znakovi stanja koje se zove osteonekroza čeljusti.
English: Confusion.
Croatian: Zbunjenost.
English: These fractures occur after minimal or no trauma and some patients experience thigh or groin pain, often associated with imaging features of stress fractures, weeks to months before presenting with a completed femoral fracture.
Croatian: Prijelomi nastaju nakon minimalne traume ili bez ikakve traume, pri čemu neki bolesnici osjete bol u natkoljenici ili preponama, a na radiološkim slikama često su prisutni znakovi stresnog prijeloma tjednima ili mjesecima prije nego što nastane potpuni prijelom bedrene kosti.
English: If a lower dose of Zometa is required, first withdraw the appropriate volume as indicated below and then dilute it further with 100 ml of infusion solution.
Croatian: Ako je potrebna niža doza Zomete, prvo izvucite odgovarajući volumen kako je navedeno niže, i potom ga dodatno razrijedite sa 100 ml otopine za infuziju.
English: Remove the following amount of Zometa solution for infusion (ml)
Croatian: Izvucite sljedeću količinu Zometa otopine za infuziju (ml)
English: Sudden coldness with fainting, limpness or collapse.
Croatian: Iznenadan osjećaj hladnoće s nesvjesticom, posrtanjem ili kolapsom.
English: While the risk is reduced with a dose of 4 mg zoledronic acid administered over 15 minutes, deterioration in renal function may still occur.
Croatian: Premda je rizik smanjen kod primjene zoledronatne kiseline u dozi od 4 mg primijenjene tijekom 15 minuta, i dalje može nastupiti pogoršanje funkcije bubrega.
English: Hypophosphataemia Adverse events occurring with frequencies < 5% were medically assessed and it was shown that these cases are consistent with the well established safety profile of Zometa (see section 4.8)
Croatian: Hipofosfatemija Štetni događaji koji nastaju s učestalošću <5% bili su medicinski procijenjeni i pokazalo se da su u skladu s dobro utvrđenim sigurnosnim profilom Zomete (vidjeti dio 4.8)
English: After initiating the infusion of zoledronic acid, the plasma concentrations of zoledronic acid rapidly increased, achieving their peak at the end of the infusion period, followed by a rapid decline to < 10% of peak after 4 hours and < 1% of peak after 24 hours, with a subsequent prolonged period of very low concentrations not exceeding 0.1% of peak prior to the second infusion of zoledronic acid on day 28.
Croatian: Nakon početka infuzije zoledronatne kiseline, koncentracija zoledronatne kiseline u plazmi brzo se povisila i postigla vršnu vrijednost na kraju razdoblja infuzije, nakon čega je uslijedilo brzo sniženje na <10% vršne vrijednosti nakon 4 sata te <1% vršne vrijednosti nakon 24 sata, a potom produljeno razdoblje vrlo niskih koncentracija koje nisu prelazile 0,1% vršne vrijednosti prije druge infuzije zoledronatne kiseline 28. dana.
English: Dyspnoea, cough, bronchoconstriction
Croatian: Dispneja, kašalj, bronhokonstrikcija
English: It is not known whether zoledronic acid is excreted into human milk.
Croatian: Nije poznato izlučuje li se zoledronatna kiselina u majčino mlijeko.
English: NR NR NR 640
Croatian: ND ND ND 640
English: Use immediately after dilution.
Croatian: Primijeniti odmah nakon razrjeđivanja.
English: Patients being treated with Zometa should not be treated with Aclasta or any other bisphosphonate concomitantly, since the combined effects of these agents are unknown.
Croatian: Bolesnici koji se liječe Zometom ne smiju istodobno uzimati Aclastu ili bilo koji drugi bisfosfonat, budući da kombinirani učinci tih tvari nisu poznati.
English: Difficulty in breathing with wheezing or coughing.
Croatian: Otežano disanje uz piskanje u plućima ili kašljanje.
English: Bradycardia, cardiac arrhythmia (secondary to hypocalcaemia)
Croatian: Bradikardija, srčana aritmija (uslijed hipokalcemije)
English: Stable for 24 hours at 2C - 8C after further dilution in 100 ml physiological saline or 5% w/v glucose solution.
Croatian: Stabilno 24 sata pri 2C - 8C nakon dodatnog razrjeđenja u 100 ml fiziološke otopine ili 5% m/V otopine glukoze.
English: Only limited pharmacokinetic data are available in patients with severe renal insufficiency (creatinine clearance < 30 ml/min).
Croatian: Za bolesnike s teškom insuficijencijom bubrega dostupni su samo ograničeni farmakokinetički podaci (klirens kreatinina manji od 30 ml/min).
English: The reduced doses for patients with renal impairment are expected to achieve the same AUC as that seen in patients with creatinine clearance of 75 ml/min.
Croatian: Očekuje se da će snižene doze u bolesnika s oštećenjem funkcije bubrega postići isti AUC kakav se opaža u bolesnika s klirensom kreatinina od 75 ml/min.
English: Zoledronic acid is not metabolised and is excreted unchanged via the kidney.
Croatian: Zoledronatna kiselina se ne metabolizira i izlučuje se neizmijenjena putem bubrega.
English: - Anti-angiogenic medicines (used to treat cancer), since the combination of these with Zometa has been associated with an increased risk of osteonecrosis of the jaw (ONJ).
Croatian: - Antiangiogene lijekove (primjenjuju se za liječenje raka), budući da je kombinacija ovih lijekova sa Zometom povezana s povećanim rizikom osteonekroze čeljusti.
English: The diluted Zometa infusion solution should be used immediately in order to avoid microbial contamination.
Croatian: Razrijeđena Zometa otopina za infuziju treba se upotrijebiti odmah kako bi se izbjegla mikrobiološka kontaminacija.
English: Patients must be maintained well hydrated prior to and following administration of Zometa.
Croatian: Bolesnici moraju biti dobro hidrirani prije i nakon primjene Zomete.
English: Any unused solution should be discarded.
Croatian: Svu neiskorištenu otopinu treba zbrinuti.
English: In an in vitro study, zoledronic acid showed low affinity for the cellular components of human blood, with a mean blood to plasma concentration ratio of 0.59 in a concentration range of 30 ng/ml to 5000 ng/ml.
Croatian: U in vitro ispitivanju, zoledronatna kiselina je pokazala niski afinitet za humane krvne stanice, uz srednju vrijednost omjera koncentracije krvi prema plazmi od 0,59 za raspon koncentracije od 30 ng/ml do 5000 ng/ml.
English: Longer-term repeat administration at doses bracketing the highest intended human therapeutic dose of zoledronic acid produced toxicological effects in other organs, including the gastrointestinal tract, liver, spleen and lungs, and at intravenous injection sites.
Croatian: Dugotrajna ponovna primjena doza koje se približavaju najvišoj terapijskoj dozi zoledronatne kiseline u ljudi proizvela je toksične učinke na drugim organima, uključujući gastrointestinalni trakt, jetru, slezenu i pluća te promjene na mjestu primjene intravenske injekcije.
English: The recommended dose in hypercalcaemia (albumin-corrected serum calcium  12.0 mg/dl or 3.0 mmol/l) is a single dose of 4 mg zoledronic acid.
Croatian: Preporučena doza kod hiperkalcemije (serumski kalcij korigiran za albumin ≥12,0 mg/dl ili 3,0 mmol/l) je jednokratna doza od 4 mg zoledronatne kiseline.
English: The imbalance observed in this trial has not been observed in other trials with zoledronic acid, including those with Zometa (zoledronic acid) 4 mg every 3-4 weeks in oncology patients.
Croatian: Opažena neravnoteža u ovom ispitivanju nije bila primijećena u drugim ispitivanjima Zomete (zoledronatne kiseline) uključujući ispitivanja zoledronatne kiseline u dozi od 4 mg primijenjene svaka 3-4 tjedna u onkoloških bolesnika.
English: Osteonecrosis of the external auditory canal (bisphosphonate class adverse reaction) and other anatomical sites including femur and hip
Croatian: Osteonekroza vanjskog slušnog kanala (nuspojava razreda bisfosfonata) i drugih anatomskih mjesta uključujući bedrenu kost i kuk
English: Solvent for Zometa Water for injections 5 ml
Croatian: Otapalo za Zometu Voda za injekcije 5 ml
English: Aseptic techniques must be followed during the preparation of the infusion.
Croatian: Tijekom pripreme infuzije moraju se primjenjivati aseptičke tehnike.
English: An extension study was conducted in order to examine the long-term general and renal safety of once yearly or twice yearly zoledronic acid over the 12-month extension treatment period in children who had completed one year of treatment with either zoledronic acid or pamidronate in the core study.
Croatian: Produžetak ispitivanja proveo se da bi se ispitala dugotrajna opća sigurnost zoledronatne kiseline i njezina sigurnost za bubrege kod primjene jedanput ili dvaput godišnje tijekom 12-mjesečnog produžetka terapijskog razdoblja u djece koja su dovršila godinu dana liječenja zoledronatnom kiselinom ili pamidronatom u glavnom ispitivanju.
English: The management plan for patients who develop ONJ should be set up in close collaboration between the treating physician and a dentist or oral surgeon with expertise in ONJ.
Croatian: Plan liječenja bolesnika koji razviju ONČ potrebno je postaviti u uskoj suradnji između liječnika i stomatologa ili oralnog kirurga sa iskustvom u liječenju ONČ.
English: Administration of 0.001 mg/kg/day subcutaneously in rats and 0.005 mg/kg intravenously once every 2-3 days in dogs for up to 52 weeks was also well tolerated.
Croatian: Doza od 0,001 mg/kg na dan primijenjena supkutano u štakora i doza od 0,005 mg/kg primijenjena intravenski u pasa jedanput svaka 2-3 dana do najviše 52 tjedna također su se dobro podnosile.
English: During bisphosphonate treatment patients should be advised to report any thigh, hip or groin pain and any patient presenting with such symptoms should be evaluated for an incomplete femur fracture.
Croatian: Bolesnicima treba savjetovati da tijekom liječenja bisfosfonatima prijave svaku bol u natkoljenici, kuku ili preponama, i svakog bolesnika s takvim simptomima treba pregledati na nepotpuni prijelom bedrene kosti.
English: • Breast-feeding (see section 4.6).
Croatian: • Dojenje (vidjeti dio 4.6)
English: Single and multiple 5- and 15-minute infusions of 2, 4, 8 and 16 mg zoledronic acid in 64 patients with bone metastases yielded the following pharmacokinetic data, which were found to be dose independent.
Croatian: Jednokratne i višekratne infuzije zoledronatne kiseline u dozi od 2, 4, 8 i 16 mg u trajanju od 5 i 15 minuta u 64 bolesnika s koštanim metastazama pružile su sljedeće farmakokinetičke podatke, za koje se pokazalo da ne ovise o dozi.
English: The unopened bottle does not require any special storage conditions.
Croatian: Za neotvorenu bočicu nisu potrebni posebni uvjeti čuvanja.
English: Zoledronic acid 4 mg was also studied in a double-blind, randomised, placebo-controlled trial in 228 patients with documented bone metastases from breast cancer to evaluate the effect of 4 mg zoledronic acid on the skeletal related event (SRE) rate ratio, calculated as the total number of SRE events (excluding hypercalcaemia and adjusted for prior fracture), divided by the total risk period.
Croatian: Zoledronatna kiselina od 4 mg također se ispitivala u dvostruko slijepom, randomiziranom, placebom kontroliranom ispitivanju u 228 bolesnika s potvrđenim koštanim metastazama karcinoma dojke da bi se procijenio učinak 4 mg zoledronatne kiseline na omjer stope koštanih događaja izračunatog kao ukupni broj koštanih događaja (bez hiperkalcemije i prilagođen s obzirom na prethodne prijelome) podijeljen s ukupnim rizičnim razdobljem.
English: Clear and colourless solution.
Croatian: Bistra i bezbojna otopina.
English: In clinical studies, Zometa has been administered concomitantly with commonly used anticancer agents, diuretics, antibiotics and analgesics without clinically apparent interactions occurring.
Croatian: U kliničkim se ispitivanjima Zometa primjenjivala istodobno s često davanim antitumorskim lijekovima, diureticima, antibioticima i analgeticima bez klinički vidljivih interakcija.
English: Each pack contains the vial with concentrate.
Croatian: Svako pakiranje sadrži bočicu s koncentratom.
English: Intravenously administered zoledronic acid is eliminated by a triphasic process: rapid biphasic disappearance from the systemic circulation, with half-lives of t½ 0.24 and t½ 1.87 hours, followed by a long elimination phase with a terminal elimination half-life of t½ 146 hours.
Croatian: Intravenski primijenjena zoledronatna kiselina eliminira se procesom u tri faze: brzim bifazičnim nestankom iz sistemskog krvotoka, uz poluvijek t1/2α od 0,24 sata i t1/2β od 1,87 sati, za kojim slijedi dugotrajna faza eliminacije uz terminalni poluvijek eliminacije t1/2γ od 146 sati.
English: Multipack (4x1 bottle)
Croatian: Višestruko pakiranje (4x1 boca)
English: Zometa recommended dose* 4.0 mg zoledronic acid 3.5 mg* zoledronic acid 3.3 mg* zoledronic acid 3.0 mg* zoledronic acid * Doses have been calculated assuming target AUC of 0.66 (mg•hr/l) (CLcr = 75 ml/min).
Croatian: Preporučena doza Zomete* 4,0 mg zoledronatne kiseline 3,5 mg* zoledronatne kiseline 3,3 mg* zoledronatne kiseline 3,0 mg* zoledronatne kiseline * Doze su izračunate uz pretpostavku da je ciljni AUC 0,66 (mg•hr/l) (CLcr = 75 ml/min).
English: Multipack (5x1 bottle)
Croatian: Višestruko pakiranje (5x1 boca)
English: - Thalidomide (a medicine used to treat a certain type of blood cancer involving the bone) or any other medicines which may harm your kidneys.
Croatian: - Talidomid (lijek za liječenje određenih vrsta raka krvi koji zahvaća kost) ili neke druge lijekove koji mogu oštetiti bubrege.