FrancophonIA/ELRC3.0 huggingface dataset:
English: After almost 4 years, nobody had had post-herpetic neuralgia in the Shingrix group compared with 18 in the placebo group.
Slovenian: Po skoraj štirih letih v skupini, ki je prejela zdravilo Shingrix, nihče ni zbolel za postherpetično nevralgijo, v skupini s placebom pa jih je zbolelo 18.
English: After just over 3 years on average, 6 adults had had shingles in the Shingrix group compared with 210 in the placebo group.
Slovenian: Po povprečno dobrih treh letih je v skupini, ki je prejela zdravilo Shingrix, za pasovcem zbolelo šest odraslih, v skupini s placebom pa 210.
English: After 4 years, 4 adults had had post-herpetic neuralgia in the Shingrix group compared with 36 in the placebo group.
Slovenian: Po skoraj štirih letih so v skupini, ki je prejela zdravilo Shingrix, za postherpetično nevralgijo zboleli štirje, v skupini s placebom pa jih je zbolelo 36.
English: Further information on Incruse Ellipta can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Nadaljnje informacije o zdravilu Incruse Ellipta so na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: 1 Previously known as Incruse.
Slovenian: 1 Predhodno znano kot zdravilo Incruse.
English: Incruse Ellipta was investigated in four main studies involving over 4,000 patients.
Slovenian: Zdravilo Incruse Ellipta so proučevali v štirih glavnih študijah, ki so vključevale več kot 4 000 bolnikov.
English: The European Medicines Agency decided that Incruse Ellipta's benefits are greater than its risks and it can be authorised for use in the EU.
Slovenian: Evropska agencija za zdravila je zaključila, da so koristi zdravila Incruse Ellipta večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
English: Incruse Ellipta0F (umeclidinium bromide) EMA/593792/2018
Slovenian: Incruse Ellipta0F (umeklidinijev bromid) EMA/593792/2018
English: The most common side effects with Incruse Ellipta (which may affect up to 1 in 10 people) are headache, nasopharyngitis (inflammation of the nose and throat), upper respiratory tract infection (nose and throat infection), sinusitis (inflammation of the sinuses), cough, urinary tract infection (infection of the structures that carry urine), and tachycardia (increased heart rate).
Slovenian: Najpogostejši neželeni učinki zdravila Incruse Ellipta (ki se lahko pojavijo pri največ 1 bolniku od 10) so glavobol, nazofaringitis (vnetje nosu in žrela), okužba zgornjih dihal (okužba nosu in žrela), sinuzitis (vnetje sinusov), kašelj, okužba sečil (okužba struktur za odvajanje urina) in tahikardija (povečan srčni utrip).
English: The main measure of effectiveness was based on changes in the patients' forced expiratory volumes (FEV1, the maximum volume of air a person can breathe out in one second).
Slovenian: Glavno merilo učinkovitosti je bila sprememba forsiranega ekspiracijskega volumna (FEV1 - največja količina zraka, ki jo oseba lahko izdihne v eni sekundi) pri bolnikih.
English: As medicines of the same class as Incruse Ellipta may have an effect on the heart and blood vessels in the brain, the company that markets Incruse Ellipta will carry out a long-term study in patients to collect further information on its safety in comparison with tiotropium.
Slovenian: Ker lahko zdravila, ki spadajo v isti razred kot zdravilo Incruse Ellipta, vplivajo na srce in krvne žile v možganih, bo podjetje, ki trži zdravilo Incruse Ellipta, pri bolnikih izvedlo dolgoročno študijo, da bo zbralo dodatne informacije o njegovi varnosti v primerjavi s tiotropijem.
English: What measures are being taken to ensure the safe and effective use of Incruse Ellipta?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Incruse Ellipta?
English: It is available as an inhalation powder in a portable inhaler device.
Slovenian: Na voljo je v obliki praška za inhaliranje v prenosnem inhalatorju.
English: Incruse Ellipta1 (umeclidinium bromide)
Slovenian: Incruse Ellipta1 (umeklidinijev bromid)
English: Incruse Ellipta received a marketing authorisation valid throughout the EU on 28 April 2014.
Slovenian: Za zdravilo Incruse Ellipta je bilo 28. aprila 2014 izdano dovoljenje za promet, veljavno po vsej EU.
English: Incruse Ellipta is used for maintenance (regular) treatment.
Slovenian: Zdravilo Incruse Ellipta se uporablja za vzdrževalno (redno) zdravljenje.
English: As for all medicines, data on the use of Incruse Ellipta are continuously monitored.
Slovenian: Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila Incruse Ellipta stalno spremljajo.
English: Side effects reported with Incruse Ellipta are carefully evaluated and any necessary action taken to protect patients.
Slovenian: Neželeni učinki, o katerih so poročali pri zdravilu Incruse Ellipta, se skrbno ovrednotijo in po potrebi se sprejmejo ukrepi za zaščito bolnikov.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Incruse Ellipta have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Incruse Ellipta upoštevati zdravstveni delavci in bolniki, so vključeni tudi v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: A double dose of Incruse Ellipta only showed small improvements compared with a single dose, which were not considered relevant.
Slovenian: Z dvojnim odmerkom zdravila Incruse Ellipta je bilo v primerjavi z enkratnim odmerkom doseženo le majhno izboljšanje tega rezultata, ki se ne šteje za pomembno.
English: Results showed that Incruse Ellipta improved lung function by an average FEV1 of 127 ml more than placebo after 12 weeks of treatment and by 115 ml more than placebo after 24 weeks of treatment.
Slovenian: Rezultati so pokazali, da je zdravilo Incruse Ellipta po 12 tednih zdravljenja izboljšalo delovanje pljuč v smislu povečanja povprečne vrednosti FEV1 za 127 ml več kot placebo, po 24 tednih pa za 115 ml več.
English: The Agency also noted that there were no major safety concerns with Incruse Ellipta, with side effects being manageable and similar to other medicines of the same class (antimuscarinic bronchodilators).
Slovenian: Ugotovila je tudi, da ni večjih pomislekov glede varnosti zdravila Incruse Ellipta, saj so njegovi neželeni učinki obvladljivi in podobni kot pri drugih zdravilih iz istega razreda (antimuskarinski bronhodilatatorji).
English: Other information about Incruse Ellipta
Slovenian: Druge informacije o zdravilu Incruse Ellipta
English: In the study comparing Incruse Ellipta with tiotropium, FEV1 improvements over 24 weeks were similar for both medicines.
Slovenian: V študiji, v kateri so zdravilo Incruse Ellipta primerjali s tiotropijem, so bila izboljšanja vrednosti FEV1 v obdobju 24 tednov pri obeh zdravilih podobna.
English: An overview of Incruse Ellipta and why it is authorised in the EU
Slovenian: Pregled zdravila Incruse Ellipta in zakaj je odobreno v EU
English: Incruse Ellipta is a medicine used to relieve the symptoms of chronic obstructive pulmonary disease (COPD) in adults.
Slovenian: Zdravilo Incruse Ellipta se uporablja za lajšanje simptomov kronične obstruktivne pljučne bolezni (KOPB) pri odraslih.
English: The Agency concluded that Incruse Ellipta was shown to be effective at improving lung function and symptoms of COPD.
Slovenian: Zaključila je, da se je zdravilo Incruse Ellipta izkazalo za učinkovito pri izboljševanju delovanja pljuč in simptomov KOPB.
English: What benefits of Incruse Ellipta have been shown in studies?
Slovenian: Kakšne koristi zdravila Incruse Ellipta so se pokazale v študijah?
English: The active substance in Incruse Ellipta, umeclidinium bromide, is a muscarinic receptor antagonist.
Slovenian: Učinkovina v zdravilu Incruse Ellipta, umeklidinijev bromid, je antagonist muskarinskih receptorjev.
English: Why is Incruse Ellipta authorised in the EU?
Slovenian: Zakaj je bilo zdravilo Incruse Ellipta odobreno v EU?
English: What is Incruse Ellipta and what is it used for?
Slovenian: Kaj je zdravilo Incruse Ellipta in za kaj se uporablja?
English: What are the risks associated with Incruse Ellipta?
Slovenian: Kakšna tveganja so povezana z zdravilom Incruse Ellipta?
English: Three studies compared Incruse Ellipta with placebo (a dummy treatment), while one study compared Incruse Ellipta with tiotropium (another medicine for COPD).
Slovenian: V treh študijah so zdravilo Incruse Ellipta primerjali s placebom (zdravilom brez učinkovine), v eni študiji pa s tiotropijem (drugim zdravilom za zdravljenje KOPB).
English: For the full list of side effects and restrictions with Incruse Ellipta, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov in omejitev pri uporabi zdravila Incruse Ellipta glejte navodilo za uporabo.
English: Incruse Ellipta can only be obtained with a prescription.
Slovenian: Predpisovanje in izdaja zdravila Incruse Ellipta je le na recept.
English: How is Incruse Ellipta used?
Slovenian: Kako se zdravilo Incruse Ellipta uporablja?
English: How does Incruse Ellipta work?
Slovenian: Kako zdravilo Incruse Ellipta deluje?
English: Incruse Ellipta contains the active substance umeclidinium bromide.
Slovenian: Zdravilo vsebuje učinkovino umeklidinijev bromid.
English: Key elements to be included in the educational material
Slovenian: Ključni elementi, ki morajo biti vključeni v izobraževalno gradivo
English: • Educational material
Slovenian: • Izobraževalno gradivo
English: If use of eltrombopag is deemed necessary, the starting dose must be 25mg once daily.
Slovenian: Če je uporaba eltrombopaga nujna, mora biti začetni odmerek 25 mg enkrat na dan.
English: The Member States must ensure that all conditions with regard to the safe and effective use of the medicinal products described below are implemented:
Slovenian: Države članice morajo zagotoviti uveljavitev vseh spodaj opisanih pogojev za varno in učinkovito uporabo zdravil:
English: • Measure serum ALT, AST and bilirubin prior to initiation of Revolade, every 2 weeks during the dose adjustment phase and monthly following establishment of a stable dose.
Slovenian: • Meritve ALT, AST in bilirubina v serumu pred uvedbo zdravila Revolade, vsaka 2 tedna med obdobjem prilagajanja odmerka in nato vsak mesec po opredelitvi stabilnega odmerka.
English: The MAH shall agree the details of an educational programme with the National Competent Authorities and must implement such programme nationally to ensure that, prior to prescribing, all physicians are provided with a healthcare professional information pack containing the following:
Slovenian: Takšen program mora izvesti nacionalno, da bodo pred predpisovanjem zdravila vsi zdravniki dobili informacijski komplet za zdravstveno osebje, ki vsebuje naslednje:
English: • Revolade should be interrupted if platelet counts increase to > 250,000/μl.
Slovenian: • Uporabo zdravila Revolade je treba prekiniti, če se število trombocitov poveča na > 250.000/µl.
English: • Awareness to prescribers of the labelled indication and warnings associated with non-indicated populations (e.g. not recommended for use in children, pregnant or lactating females, other off label uses).
Slovenian: • Pri zdravnikih zagotoviti poznavanje odobrenih indikacij in opozoril, povezanih z uporabo pri neindiciranih populacijah (npr. uporaba zdravila ni priporočljiva pri otrocih, nosečnicah in doječih ženskah, druge uporabe zunaj okvira odobrenih indikacij).
English: • Discontinue Revolade if ALT levels increase (≥ 3X the upper limit of normal [ULN]) and are: - progressive, or - persistent for > 4 weeks, or - accompanied by increased direct bilirubin, or - accompanied by clinical symptoms of liver injury or evidence for hepatic decompensation.
Slovenian: • Prekinitev uporabe zdravila Revolade, če se pojavi zvišanje ALT (≥ 3-kratna zgornja normalna meja [ZNM]), ki: - napreduje ali - traja > 4 tedne ali - ga spremlja zvišanje direktnega bilirubina ali - ga spremljajo klinični simptomi okvare jeter ali znaki jetrne dekompenzacije.
English: Once the platelet count is < 100,000/μl, reinitiate therapy at a reduced daily dose.
Slovenian: Ko je število trombocitov < 100.000/µl, znova začnite zdravljenje z manjšim dnevnim odmerkom.
English: • Educate patients on the appropriate administration of Revolade (e.g. titration of Revolade, fooddrug interaction, dose recommendations for special populations [e.g. east Asians]).
Slovenian: • Seznanitev bolnikov z ustrezno uporabo zdravila Revolade (npr. titriranjem tega zdravila, interakcijah s hrano/zdravili, priporočili za odmerjanje v posebnih populacijah [npr. pri vzhodnih Azijcih].
English: • Eltrombopag should not be used in patients with hepatic impairment (Child Pugh score ≥ 5) unless the expected benefit outweighs the identified risk of portal venous thrombosis.
Slovenian: • Pri bolnikih z zmerno do hudo okvaro jeter se eltrombopag ne sme uporabljati, razen če pričakovana korist zdravljenja prevlada nad znanim tveganjem za pojav tromboze portalne vene.
English: • Educate patients about the potential for hepatic enzyme elevations, importance of monthly laboratory monitoring of ALT and AST, as well as the signs and symptoms associated with liver injury (e.g. jaundice).
Slovenian: • Seznanitev bolnikov z možnostjo zvišanja jetrnih encimov, pomenom vsakomesečnih laboratorijskih kontrol ALT in AST ter znaki in simptomi, ki spremljajo okvaro jeter (npr. zlatenica).
English: • Educate patients about chronic liver disease and the risk of thromboembolic events.
Slovenian: • Seznanitev bolnikov o bolnikih s kronično boleznijo jeter in tveganjem trombemboličnih dogodkov.
English: • Educate patients about the potential for thromboembolic events (TEE) in patients with chronic ITP and those known risk factors for thromboembolic events (e.g., Factor V Leiden, ATIII deficiency, antiphospholipid syndrome).
Slovenian: • Seznanitev bolnikov z možnostjo trombemboličnih dogodkov pri kronični ITP in v primeru znanih dejavnikov tveganja za trombembolične dogodke (npr. faktor V Leiden, pomanjkanje ATIII, antifosfolipidni sindrom).
English: • A dose reduction is recommended for ITP patients with platelet counts between 150,000250,000/μl.
Slovenian: • Bolnikom, ki imajo število trombocitov od 150.000 do 250.000/µl, je odmerek priporočljivo zmanjšati.
English: • Summary of Product Characteristics (SmPC) and Package Leaflet and Labelling
Slovenian: • Povzetek glavnih značilnosti zdravila in navodilo za uporabo
English: 20 November 2015
Slovenian: Datum prve odobritve: 20. november 2015
English: It has been reported that pemetrexed may cause fatigue.
Slovenian: Poročali so, da lahko pemetreksed povzroči utrujenost.
English: Based on the planned date of your infusion of pemetrexed and/or on the status of your kidney function, your doctor needs to advise you on which medicines you can take and when you can take them.
Slovenian: Na podlagi načrtovanega datuma vaše infuzije pemetrekseda in/ali glede na delovanje vaših ledvic vam mora zdravnik svetovati, katera zdravila lahko jemljete in kdaj jih lahko jemljete.
English: Reconstituted and infusion solution: The product should be used immediately.
Slovenian: Rekonstituirane raztopine in raztopine za infundiranje: Izdelek moramo uporabiti nemudoma.
English: Creatinine elevation 10.7 Creatinine clearance decreased**
Slovenian: Povišan kreatinin 10,7 Znižan očistek kreatinina**
English: Calculate the dose and the number of Pemetrexed Hospira vials needed.
Slovenian: Izračunajte odmerek in število potrebnih vial zdravila Pemetreksed Hospira.
English: Do not use Pemetrexed Hospira - if you are allergic to pemetrexed or any of the other ingredients of this medicine (listed in section 6).
Slovenian: Ne uporabljajte zdravila Pemetreksed Hospira - če ste alergični na pemetreksed ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Frequency estimate: Very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000) and not known (cannot be estimated from available data).
Slovenian: Pogostnosti so določene kot: zelo pogosto (≥1/10), pogosto (≥ 1/100 do < 1/10), občasno (≥ 1/1.000 do < 1/100), redko (≥ 1/10.000 do < 1/1.000), zelo redko (< 1/10.000) in neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
English: Driving and using machines Pemetrexed Hospira may make you feel tired.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Pemetreksed Hospira lahko povzroči, da se boste počutili utrujene.
English: Instructions for use, handling and disposal
Slovenian: Navodila za uporabo, ravnanje z zdravilom in odstranjevanje
English: For intravenous use
Slovenian: Za intravensko uporabo
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C to 8°C.
Slovenian: Če zdravila, pripravljenega za uporabo, ne uporabimo takoj, je za čase shranjevanja in pogoje pred uporabo odgovoren uporabnik, in naj bi ne presegali 24 ur pri 2 do 8 °C.
English: There are no data from the use of pemetrexed in pregnant women; but pemetrexed, like other antimetabolites, is suspected to cause serious birth defects when administered during pregnancy.
Slovenian: Podatkov o uporabi pemetrekseda pri nosečnicah ni, a za pemetreksed, kot za druge antimetabolite, sumimo, da povzroča resne prirojene okvare, če ga dajemo med nosečnostjo.
English: Pemetrexed Hospira can have a minor or moderate influence on ability to drive and use machines.
Slovenian: Zdravilo Pemetreksed Hospira ima blag ali zmeren vpliv na sposobnost vožnje in upravljanja s stroji.
English: Before each infusion you will have samples of your blood taken to evaluate if you have sufficient kidney and liver function and to check that you have enough blood cells to receive Pemetrexed Hospira.
Slovenian: Pred vsako infuzijo vam bomo odvzeli vzorce krvi za vrednotenje delovanja vaših ledvic in jeter ter oceno, ali imate dovolj krvnih celic za prejemanje zdravila Pemetreksed Hospira.
English: This medicine is for single use only; any unused solution must be disposed of in accordance with local requirements.
Slovenian: To zdravilo je namenjeno samo enkratni uporabi, morebitno neporabljeno raztopino je treba odstraniti v skladu z lokalnim predpisom.
English: Upon recovery, patients should be re-treated using the guidelines in Tables 1, 2, and 3, which are applicable for Pemetrexed Hospira used as a single agent or in combination with cisplatin.
Slovenian: Po okrevanju bolnike ponovno zdravimo z uporabo smernic v Preglednicah 1, 2 in 3, ki veljajo za zdravilo Pemetreksed Hospira, če jo uporabljamo kot edino učinkovino ali v kombinaciji s cisplatinom.
English: CZ Pfizer, spol.
Slovenian: Pfizer, spol.
English: When using Pemetrexed Hospira in combination with cisplatin:
Slovenian: Kadar uporabljamo Pemetreksed Hospira v kombinaciji s cisplatinom:
English: If you have an accumulation of fluid around your lungs, your doctor may decide to remove the fluid before giving you Pemetrexed Hospira.
Slovenian: Če se vam okrog pljuč nabira tekočina, se bo zdravnik morda odločil tekočino pred dajanjem zdravila Pemetreksed Hospira odstraniti.
English: • Fever or infection (common): if you have a temperature of 38ºC or greater, sweating or other signs of infection (since you might have fewer white blood cells than normal which is very common).
Slovenian: • Povišana telesna temperatura ali okužba (pogosto): če se pojavi temperatura 38 ºC ali višja, znojenje ali drugi znaki okužbe (ker imate lahko manj belih krvničk kot normalno, kar je zelo pogosto).
English: A significant increase in the incidence of possibly study-drug-related Grade 3/4 neutropenia was observed with longer exposure to pemetrexed (≤6 cycles: 3.3%, >6 cycles: 6.4%: p=0.046).
Slovenian: Znatno povečanje pojavnosti nevtropenije stopnje 3/4, ki je lahko povezano s preučevanim zdravilom, so opazili pri dolgotrajnejši izpostavljenosti pemetreksedu (≤ 6 ciklov: 3,3 %, > 6 ciklov: 6,4 %: p=0,046).
English: If you have been recently vaccinated, please tell your doctor, as this can possibly cause bad effects with Pemetrexed Hospira.
Slovenian: Če ste bili nedavno cepljeni, prosimo, povejte to zdravniku saj lahko to ob jemanju zdravila Pemetreksed Hospira povzroča škodljive učinke.
English: Treatment with Pemetrexed Hospira should be discontinued if a patient experiences any haematologic or non-haematologic Grade 3 or 4 toxicity after 2 dose reductions or immediately if Grade 3 or 4 neurotoxicity is observed.
Slovenian: Zdravljenje z zdravilom Pemetreksed Hospira moramo prekiniti, če bolnik izkusi kakršnokoli hematološko ali nehematološko toksičnost stopnje 3 ali 4 po 2 znižanjih odmerka ali nemudoma, če opazimo nevrološko toksičnost stopnje 3 ali 4.
English: Pemetrexed Hospira is a medicine used in the treatment of cancer.
Slovenian: Pemetreksed Hospira je zdravilo, ki ga uporabljamo pri zdravljenju raka.
English: Hospira UK Limited
Slovenian: Izdelovalec Hospira UK Limited Horizon
English: The dose of Pemetrexed Hospira is 500 milligrams for every square metre of your body's surface area.
Slovenian: Odmerek zdravila Pemetreksed Hospira je 500 miligramov za vsak kvadratni meter površine vašega telesa.
English: What you need to know before you use Pemetrexed Hospira
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Pemetreksed Hospira
English: What Pemetrexed Hospira is and what it is used for
Slovenian: Kaj je zdravilo Pemetreksed Hospira in za kaj ga uporabljamo
English: Corticosteroids: your doctor will prescribe you steroid tablets (equivalent to 4 milligram of dexamethasone twice a day) that you will need to take on the day before, on the day of, and the day after Pemetrexed Hospira treatment.
Slovenian: Kortikosteroidi: zdravnik vam bo predpisal tablete steroidov (ustrezno 4 miligramom deksametazona dvakrat dnevno), ki jih boste morali jemati dan pred zdravljenjem z zdravilom Pemetreksed Hospira, na dan zdravljenja in na dan po zdravljenju z zdravilom Pemetreksed Hospira.
English: Please tell your doctor if you are taking any medicine for pain or inflammation (swelling), such as medicines called “nonsteroidal anti-inflammatory drugs” (NSAIDs), including medicines purchased without a doctor's prescription (such as ibuprofen).
Slovenian: Druga zdravila in zdravilo Pemetreksed Hospira Prosimo, povejte zdravniku, če jemljete kaka zdravila proti bolečinam ali vnetju (oteklinam), denimo zdravila, imenovana “nesteroidna protivnetna zdravila” (NSAID), vključno z zdravili, ki ste jih dobili brez recepta (kot denimo ibuprofen).
English: Refer to section 2 “Pemetrexed Hospira contains sodium”.
Slovenian: Glejte poglavje 2 “Pemetreksed Hospira vsebuje natrij”.
English: When prepared as directed, chemical and physical in-use stability of reconstituted and infusion solutions of pemetrexed were demonstrated for 24 hours at refrigerated temperature (2°C to 8°C).
Slovenian: Po pripravi po navodilih so kemijsko in fizikalno obstojnost za uporabo rekonstituiranih raztopin pemetrekseda in raztopin pemetrekseda za infundiranje pokazali za 24 ur v hladilniku (2°C do 8°C).
English: If patients develop non-haematologic toxicities ≥ Grade 3 (excluding neurotoxicity), Pemetrexed Hospira should be withheld until resolution to less than or equal to the patient's pre-therapy value.
Slovenian: Če se pri bolnikih razvijejo nehematološke toksičnosti ≥ stopnje 3 (z izjemo nevrološke toksičnosti), moramo dajanje zdravila Pemetreksed Hospira prekiniti, dokler se vrednosti ne povrnejo na manjše ali enake, kot jih je imel bolnik pred zdravljenjem.
English: Immune mediated haemolytic anaemia (antibody-mediated destruction of red blood cells) Hepatitis (inflammation of the liver)
Slovenian: Imunsko pogojena hemolitična anemija (propad rdečih krvnih celic, ki ga povzročijo protiteles) Hepatitis (vnetje jeter)
English: You will always receive Pemetrexed Hospira by infusion into one of your veins.
Slovenian: Zdravilo Pemetreksed Hospira boste vedno prejeli v obliki infuzije v veno.