FrancophonIA/ELRC3.0 huggingface dataset:
English: Candesartan does not influence ACE or other enzyme systems usually associated with the use of ACE inhibitors.
Maltese: Candesartan ma jinfluenzawx ACE, jew sistemi ta' enżimi oħra normalment assoċjati ma l-użu ta' inibituri ACE.
English: The terminal half-life (t½) of candesartan is approximately 9 hours.
Maltese: Il-half-life terminali (t½) ta' candesartan hija ta' madwar 9 sigħat.
English: The use of AIIRAs is contraindicated during the second and third trimesters of pregnancy (see sections 4.3 and 4.4).
Maltese: L-Użu ta' AIIRAs huwa kontraindikat waqt it-tieni u t-tielet trimestri tat-tqala (ara sezzjoni 4.3 u 4.4).
English: Sleep disturbances, depression, restlessness
Maltese: Disturbi fl-irqad, depressjoni, irrekwitezza
English: Treatment with a thiazide diuretic may impair glucose tolerance.
Maltese: Kura b' dijuretiku thiazide tista tnaqqas it-tolleranza għall-glucose.
English: The candesartan cilexetil/hydrochlorothiazide combination 32 mg/25 mg was significantly more effective than the 32 mg/12.5 mg combination, and the overall mean blood pressure reductions were 16/10 mmHg and 13/9 mmHg, respectively.
Maltese: It-taħlita ta' candesartan cilexetil/hydrochlorothiazide 32 mg/25 mg kienet aktar effettiva mit-taħlita ta' 32 mg/12.5 mg u ttnaqqis totali fil-pressjoni kienu 16/10 mmHg u 13/9 mmHg rispettivament.
English: Total plasma clearance of candesartan is about 0.37 ml/min/kg, with a renal clearance of about 0.19 ml/min/kg.
Maltese: It-tneħħija totali ta' candesartan mill-plażma hija ta' madwar 0.37 ml/min/kg, bi tneħħija millkliewi ta' madwar 0.19 ml/min/kg.
English: Jaundice (intrahepatic cholestatic jaundice)
Maltese: Suffejra (suffejra ta' kolestażi intraepatika)
English: Carbenoxolone (for treatment of oesophageal disease, or oral ulcers).
Maltese: • Carbenoxolone (għal kura ta' mard esofaġali, jew ulċeri orali).
English: In two clinical studies (randomised, double-blind, placebo controlled, parallel group) including 275 and 1524 randomised patients, respectively, the candesartan cilexetil/hydrochlorothiazide combinations 32 mg/12.5 mg and 32 mg/25 mg resulted in blood pressure reductions of 22/15 mmHg and 21/14 mmHg, respectively, and were significantly more effective than the respective monocomponents.
Maltese: F' żewġ studji kliniċi (randomised, double blind, ikkontrollati bi plaċebo, grupp parallel) jinkludu 275 u 1524 pazjent randomised, rispettivament, it-taħlita ta' candesartan cilexetil/hydrochlorothiazide 32 mg/12.5 mg u 32 mg/25 mg irriżultat fi tnaqqis fil-pressjoni ta' 22/15 mmHg u 21/14 mmHg, rispettivament, u kienu sinifikament aktar effettivi mis-sustanzi rispettivi waħedhom.
English: Thiazides may reduce the renal excretion of cytotoxic medicinal products (e.g. cyclophosphamide, methotrexate) and potentiate their myelosuppressive effects.
Maltese: Thiazides jistgħu jnaqqsu l-eskrezzjoni mill-kliewi ta' prodotti mediċinali ċitotossiċi (eż. cyclophosphamide, methotrexate) u jqawwi l-effetti majelosuppressivi tagħhom.
English: It is important that you are aware of what these side effects may be.
Maltese: Huwa importani li tkun taf x' jistgħu jkunu dawn l-effetti sekondarji.
English: Renal dysfunction and interstitial nephritis
Maltese: Glucosurja Anormalita renali, nefrite interstizjali
English: Water tablets (diuretics).
Maltese: • Pilloli ta' l-ilma (dijuretiċi).
English: Atacand Plus is contraindicated in patients with severe hepatic impairment and/or cholestasis (see section 4.3).
Maltese: Atacand Plus huwa kontraindikat f' pazjenti b'indeboliment tal-fwied qawwi u/jew kolestasi (ara sezzjoni 4.3)
English: Acetylsalicylic acid (if you are taking more than 3 g each day) (medicine to relieve pain and inflammation).
Maltese: • Acetylsalicylic acid (jekk qed tieħu aktar minn 3 g kuljum) (mediċini li jnaqqsu l-uġigħ u l infjammazzjoni).
English: Following an oral dose of 14C-labelled candesartan cilexetil, approximately 26% of the dose is excreted in the urine as candesartan and 7% as an inactive metabolite while approximately 56% of the dose is recovered in the faeces as candesartan and 10% as the inactive metabolite.
Maltese: Wara doża mill-ħalq ta' candesartan cilexetil tikkettat b'14C, madwar 26% mid-doża titneħħa fl-awrina bħala candesartan u 7% titneħħa bħala l-metabolit mhux attiv filwaqt li madwar 56% mid-doża hija rkuprata mill-ippurgar bħala candesartan u 10% tiġi rkuprata bħala l-metabolit mhux attiv.
English: The safety and efficacy of Atacand Plus in children aged between birth and 18 years have not been established.
Maltese: Is-sigurtà u l-effikaċja ta' Atacand Plus fit-tfal ta' età mit-twelid sa 18-il sena ma ġewx stabbiliti.
English: In a double-blind randomised study, Atacand Plus 16 mg/12.5 mg once daily reduced blood pressure significantly more, and controlled significantly more patients, than the combination losartan/hydrochlorothiazide 50 mg/12.5 mg once daily.
Maltese: Fi studju randomised u double blind, Atacand Plus 16 mg/12.5 mg mogħti darba kuljum naqqas il-pressjoni b' mod aktar sinifikanti u kkontrolla pazjenti b' mod aktar sinifikanti milli t-taħita ta' losartan/hydrochlorothiazide 50 mg/12.5 mg darba kuljum.
English: Diuretic-induced hypokalaemia and hypomagnesaemia predisposes to the potential cardiotoxic effects of digitalis glycosides and antiarrhythmics.
Maltese: Ipokalimja u ipomagnesemija indotti b' dijuretiċi jwasslu għall-effetti potenzjali kardjotossiċi ta' glikosidi bid- digitalis u antiarritmiċi.
English: Angiotensin II is the primary vasoactive hormone of the renin-angiotensin-aldosterone system and plays a role in the pathophysiology of hypertension and other cardiovascular disorders.
Maltese: Angiotensin II huwa l-ormon primarju vażoattiv tas-sistema ta' renin-angiotensin-aldosterone u għandu rwol fil-patofiżjoloġija tal-pressjoni għolja u ta' disturbi kardjovaskulari oħra.
English: • Hydrochlorothiazide belongs to a group of medicines called diuretics (water tablets).
Maltese: • Hydrochlorothiazide jippartjeni lil grupp ta' mediċini li jissejħu dijuretiċi (pilloli ta' l-ilma).
English: Calcium or Vitamin D supplements.
Maltese: • Supplimenti tal-calcium jew vitamina D.
English: Large clinical studies have shown that long-term treatment with hydrochlorothiazide reduces the risk for cardiovascular morbidity and mortality.
Maltese: Studji kliniċi kbar wrew li kura fit-tul b' hydrochlorothiazide tnaqqas ir-riskju ta' morbidita u mortalita kardjuvaskulari.
English: Common Weakness Rare
Maltese: Komuni Rari
English: Approximately 70% of an oral dose is eliminated in the urine within 48 hours.
Maltese: Bejn wieħed u ieħor 70% ta' doża orali tiġi eliminata flawrina fi żmien 48 siegħa.
English: In patients whose vascular tone and renal function depend predominantly on the activity of the reninangiotensin-aldosterone system (e.g. patients with severe congestive heart failure or underlying renal disease, including renal artery stenosis), treatment with medicinal products that affect this system including AIIRAs, has been associated with acute hypotension, azotaemia, oliguria or, rarely, acute renal failure.
Maltese: F'pazjenti li t-ton vaskulari u l-funzjoni tal-kliewi tagħhom jiddependu l-aktar mill-attività tassistema ta' renin-angiotensin-aldosterone (eż. pazjenti b'insuffiċjenza konġestiva tal-qalb qawwija jew meta diġà jkun hemm mard tal-kliewi li jinkludi stenożi tal-arterja renali), il-kura bi prodotti mediċinali oħra li jaffettwaw din is-sistema, inkluż AIIRAs, kienu assoċjati ma' pressjoni baxxa akuta, ażotemija, oligurja jew, b'mod rari, indeboliment akut tal-kliewi.
English: Angiotensin II Receptor Antagonists (AIIRAs):
Maltese: Antagonisti tar-riċettur tal-anġjotensina- II (AIIRAs)
English: Refractory hypokalaemia and hypercalcaemia.
Maltese: Ipokalimja u iperkalċimja refrattorji.
English: This medicinal product contains lactose, as an excipient, and patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Maltese: Dan il-prodott mediċinali fih il-lactose, bħala sustanza mhux attiva u pazjenti bi problemi ereditarji rari ta' intolleranza għall-galactose, defiċjenza ta' Lapp lactase jew malassorbiment ta' glucosegalactose m'għandhomx jieħdu din il- mediċina.
English: High temperature (fever).
Maltese: • Temperatura għolja (deni)
English: Medicinal products that affect the renin-angiotensin-aldosterone system, including angiotensin II receptor antagonists (AIIRAs), may increase blood urea and serum creatinine in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney.
Maltese: Prodotti mediċinali li jaffettwaw is-sistema ta' renin-angiotensin-aldosterone, li jinkludu lantagonisti tar-riċetturi ta' angiotensin II (AIIRAs), jistgħu jżidu l-urea fid-demm u l-krejatinina fisserum f'pazjenti li għandhom stenożi bilaterali tal-arterji tal-kilwa jew li għandhom stenożi talarterja lejn kilwa unika.
English: Thiazides should be discontinued before carrying out tests for parathyroid function.
Maltese: Thiazides għadhom jitwaqqfu qabel ma jsiru testijiet dwar il-funzjoni tal-partirojde.
English: Important information about some of the ingredients of Atacand Plus Atacand Plus contains lactose which is a type of sugar.
Maltese: Informazzjoni importanti fuq xi sustanzi mhux attivi ta' Atacand Plus Atacand Plus fiħ lactose li huwa tip ta' zokkor.
English: The relative bioavailability of a tablet formulation of candesartan cilexetil compared with the same oral solution is approximately 34% with very little variability.
Maltese: Il-bijodisponibiltà relattiva tal-formulazzjoni tal-pillola mqabbla mal-istess soluzzjoni orali hija ta' madwar 34% bi ftit li xejn varjabbilità.
English: Barbiturates (a type of sedative also used to treat epilepsy).
Maltese: • Barbiturati (tip ta' sedattiv jintuża wkoll għal kura tal-epilessija).
English: Thiazides, including hydrochlorothiazide, can cause fluid or electrolyte imbalance (hypercalcaemia, hypokalaemia, hyponatraemia, hypomagnesaemia and hypochloraemic alkalosis).
Maltese: Thiazides li jinkludu hydrochlorothiazide jista jikkawża żbilanċ fil-fluidi jew elektroliti (iperkalċimija, ipokalimja, iponatrimija, ipomagniżimija u alkalożi ipoklorimika)
English: It contains two active ingredients: candesartan cilexetil and hydrochlorothiazide.
Maltese: Fiħ żewġ sustanzi attivi candesartan cilexetil u hydrochlorothiazide.
English: The half-life of hydrochlorothiazide remains unchanged (approximately 8 h) after administration of hydrochlorothiazide in combination with candesartan cilexetil.
Maltese: Il-half-life ta' hydrochlorothiazide jibqa l-istess (bejn wieħed u ieħor 8 sigħat) wara li jingħata hydrochlorothiazide ma candesartan cilexetil.
English: Second and third trimesters of pregnancy (see sections 4.4 and 4.6) Severe renal impairment (creatinine clearance < 30 ml/min/1.73 m2 BSA).
Maltese: (ara sezzjoni 4.4 u 4.6) Indeboliment tal-kliewi qawwi (tneħħija tal- krejatinina < 30 ml/min/ 1.73 m2 l-erja tas-superfiċe tal- ġisem
English: Hydrochlorothiazide The terminal t½ of hydrochlorothiazide is prolonged in patients with renal impairment.
Maltese: Hydrochlorothiazide It-t½ terminali ta' hydrochlorothiazide huwa mtawwal f' pazjenti b' indeboliment tal-kliewi.
English: Dose titration with the individual components (candesartan cilexetil and hydrochlorothiazide) is recommended.
Maltese: Żieda fid-doża tal-komponenti individwali ( candesartan cilexetil u hydrochlorothiazide) hija rakkomandata.
English: Symptoms such as dizziness, hypotension, thirst, tachycardia, ventricular arrhythmias, sedation/impairment of consciousness and muscle cramps can also be observed.
Maltese: Sintomi bħal sturdament, pressjoni baxxa, għaċċ, takikardija, arritmija ventrikulari, sedazzjoni/indeboliment tal-koxjenza u krampi tal-muskoli jista wkoll jiġu osservati.
English: Respiratory, thoracic and mediastinal disorders
Maltese: Disturbi respiratorji, torassiċi u medjastinali
English: In elderly subjects (over 65 years), Cmax and AUC of candesartan are increased by approximately 50% and 80%, respectively in comparison to young subjects.
Maltese: Fl-anzjani (li għandhom aktar minn 65 sena) is-Cmax u l-AUC ta' candesartan jiżdiedu b'madwar 50% u 80%, rispettivament speċjalment meta mqabbla ma' individwi żgħar.
English: Hydrochlorothiazide crosses the placenta.
Maltese: Hydrochlorothiazide jgħaddi mill-plaċenta.
English: In double-blind, randomised studies, the incidence of adverse events, especially cough, was lower during treatment with Atacand Plus than during treatment with combinations of ACE inhibitors and hydrochlorothiazide.
Maltese: Fi studji randomised u double blind, l-inċidenza ta' avvenimenti vversi, speċjalment sogħla, kienet aktar baxxa waqt kura b' Atacand Plus milli waqt kura b' taħlita ta' inibituri ACE u hydrochlorothiazide.
English: The usual dose of Atacand Plus is one tablet once a day Swallow the tablet with a drink of water.
Maltese: Id-doża normali ta' Atacand Plus hija ta' pillola waħda darba kuljum.
English: Patients with intravascular volume depletion
Maltese: Tnaqqis fil-volum intravaskulari
English: Based on the pharmacological mechanism of action of hydrochlorothiazide its use during the second and third trimesters may compromise foeto-placental perfusion and may cause foetal and neonatal effects like icterus, disturbance of electrolyte balance and thrombocytopenia.
Maltese: Skond il-mekkaniżmu farmakoloġiku tal-azzjoni ta' hydrochlorothiazide, l-użu tiegħu waqt it-tieni u t-tielet trimestri jista' jikkomprometti l-perfużjoni tal-plaċenta tal-fetu u jista' jikkawża effetti fil-fetu jew qabel it-twelid bħal ikteru, disturbi fil-bilanċ elektrolitiku u tromboċitopenija
English: In clinical trials with candesartan cilexetil/hydrochlorothiazide, adverse reactions were limited to those that were reported previously with candesartan cilexetil and/or hydrochlorothiazide.
Maltese: Fi provi kliniċi b' candesartan cilexetil/hydrochlorothiazide, reazzjonijiet avversi kienu limitati għal dawk li kienu rrappurtati qabel b' candesartan cilexetil u/jew hydrochlorothiazide.
English: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with Angiotensin Converting Enzyme (ACE) inhibitors or hydrochlorothiazide.
Maltese: Żidiet riversibbli fil-konċentrazzjonijiet ta' lithium fis-serum u fit-tossiċità kienu rrappurtati waqt għoti konkomitanti ta' lithium u impedituri ta' ACE jew hydrochlorothiazide.
English: Exposure to AIIRA therapy during the second and third trimesters is known to induce human fetotoxicity (decreased renal function, oligohydramnios, skull ossification retardation) and neonatal toxicity (renal failure, hypotension, hyperkalaemia) (see section 5.3).
Maltese: Huwa magħruf li esponiment għall- kura b' AIIRA waqt it-tieni u t-tielet trimestri tikkawża tossiċita tal-fetu uman (tnaqqis tal-funzjoni renali, oligoidramnios, ossifikazzjoni tal-kranju retardata) u tossiċita neonata (insuffiċjenza renali, pressjoni baxxa, livell għoli ta' potassju) (ara sezzjoni 5.3). Jekk l-espożizzjoni għall AIIRAs issir fit-tieni trimestru eżami ultra soniku tal-kliewi u l-kranju huwa rakkomandat.
English: Common Hyperglycaemia, hyperuricaemia, electrolyte imbalance (including hyponatraemia and hypokalaemia)
Maltese: Ipergliċemija, iperuriċemija, żbilanċ elektrolitiku (iponatrimija, ipokalimja)
English: The main manifestation of an overdose of hydrochlorothiazide is acute loss of fluid and electrolytes.
Maltese: Doża eċċessiva ta' hydrochlorothiazide tidher l-aktar x' aktarx bħala nuqqas akut ta' fluwidi u elektrolitiċi.
English: Medicines to lower your cholesterol, such as colestipol or cholestyramine.
Maltese: • Mediċini li jbaxxu l-kolesterol, bħal colestipol jew cholestyramine.
English: Very rare Cough
Maltese: Mhux komuni Rari
English: The absorption of hydrochlorothiazide is reduced by colestipol or cholestyramine.
Maltese: L-assorbiment ta' hydrochlorothiazide huwa mnaqqas b' colestipol jew cholestyramine.
English: Common Light-headedness, vertigo Rare
Maltese: Rass ħafifa, vertiġni Parasteżija
English: In a randomised, double-blind, parallel group clinical study including 1975 randomised patients not optimally controlled on 32 mg candesartan cilexetil once daily, the addition of 12.5 mg or 25 mg hydrochlorothiazide resulted in additional blood pressure reductions.
Maltese: Fi studju kliniku randomised, double blind, grupp parallel li jinkludi 1975 pazjent randomised mhux ikkontrollat b' mod xieraq fuq candesartan cilexetil 32 mg darba kuljum, iż-żieda ta' 12.5 mg jew 25 mg hydrochlorothiazide irriżulta f' tnaqqis addizzjonali tal-pressjoni.
English: Muscle cramps.
Maltese: • Krampi tal-muskolu.
English: Loop diuretics are preferred to thiazides in this population.
Maltese: Dijuretiċi loop huma preferuti minn dawk thiazide f' din il-popolazzjoni.
English: Hydrochlorothiazide may increase the risk of acute renal insufficiency especially with high doses of iodinated contrast media.
Maltese: Hydrochlorothiazide jista jżid ir-riskju ta' insuffiċjenza akuta tal-kliewi speċjalment b' dożi għolja ta' kuntrast ta' media jodinat.
English: Medicines to control your heart beat (antiarrhythmic agents) such as digoxin and beta-blockers.
Maltese: • Mediċini li jikkontrollawlek it-taħbit tal-qalb ( sustanzi antiarritmiċi) bħal digoxin u beta blockers.
English: Candesartan cilexetil/hydrochlorothiazide is similarly effective in patients irrespective of age and gender.
Maltese: Candesartan cilexetil/hydrochlorothiazide huwa effettiv l-istess f' pazjenti irrispettivament mill-eta u s-sess.
English: Dose titration of candesartan cilexetil is recommended in patients with mild to moderate renal impairment (creatinine clearance ≥ 30 ml/min/1.73 m2 Body Surface Area (BSA)) before treatment with Atacand Plus (the recommended starting dose of candesartan cilexetil is 4 mg in these patients).
Maltese: Aġġustar fid-doża ta' candesartan cilexetil huwa rakkomandat f' pazjenti b' indeboliment tal-kliewi ħafif jew moderat (tneħħija tal- krejatinina > 30 ml/min/ 1.73 m2 l-erja tas-superfiċe tal- ġisem qabel kura b' Atacand Plus ( id-doża rakkomandata ta candesartan cilexetil li wieħed għandu jibda biha hija ta' 4 mg f' dawn il-pazjenti).
English: Do not take Atacand Plus if: you are allergic (hypersensitive) to candesartan cilexetil or hydrochlorothiazide or any of the other ingredients of Atacand Plus (see section 6).
Maltese: • inti allerġiku (tbati minn sensittivita' eċċessiva) għall-candesartan cilexetil jew hudrochlorothiazide jew sustanzi oħra ta' Atacand Plus (ara sezzjoni 6).
English: The antagonism of the AT1 receptors results in dose related increases in plasma renin levels, angiotensin I and angiotensin II levels, and a decrease in plasma aldosterone concentration.
Maltese: L-antagoniżmu tarriċetturi ta' angiotensin II (AT1) iwassal għal żidiet relatati mad-doża fil-livelli ta' renin fil-plażma, fil-livelli ta' angiotensin I u angiotensin II, u fi tnaqqis tal-konċentrazzjoni ta' aldosterone filplażma.
English: In a pooled analysis of clinical trial data of hypertensive patients, adverse reactions with candesartan cilexetil were defined based on an incidence of adverse events with candesartan cilexetil at least 1% higher than the incidence seen with placebo.
Maltese: F' analiżi pooled ra' dejta minn provi kliniċi fuq pazjenti bi pressjoni għolja, reazzjonijiet avversi b' candesartan cilexetil kienu mfissra fuq bażi ta' inċidenza ta' każijiet avversi b' candesartan cilexetil mill-anqas 1 % ogħla mill-inċidenza li dehret bi plaċebo.
English: Addition of hydrochlorothiazide potentiates the nephrotoxicity of candesartan.
Maltese: Żieda ta' hydrochlorothiazide tqawwi n-nefrotossiċita ta' candesartan.
English: Data from in vitro and in vivo genotoxicity testing indicate that candesartan and hydrochlorothiazide are unlikely to exert any mutagenic or clastogenic activity under conditions of clinical use.
Maltese: Dejta minn ittestjar in vitro u in vivo għal ġenotossiċità tindika li candesartan u hydrochlorothiazide ma jagħmilx użu minn attivitajiet mutaġeniċi jew klastoġeniċi fil-kundizzjonijiet tal-użu kliniku.
English: The effect of nondepolarising skeletal muscle relaxants (e.g. tubocurarine) may be potentiated by hydrochlorothiazide.
Maltese: L-effett ta' relassanti muskolo-skelitiċi mhux depolariżżanti (eż. tubocurarine) jista jitkabbar b' hydrochlorothiazide.
English: The table below presents adverse reactions with hydrochlorothiazide monotherapy usually with doses of 25 mg or higher.
Maltese: It-tabella t' hawn taħt tippreżenta reazzjonijiet avversi b' hydrochlorothiazide bħala monoterapija normalment b' dożi ta' 25 mg jew aktar.
English: HOW TO STORE ATACAND PLUS
Maltese: Jekk tieqaf tuża Atacand Plus
English: When clinically appropriate a direct change from monotherapy to Atacand Plus may be considered.
Maltese: Meta klinikament xieraq tibdil dirett minn monoterapija għall- Atacand Plus jista jiġi kkunsidrat.
English: Fever
Maltese: Pillola
English: Concomitant use of Atacand Plus and potassium-sparing diuretics, potassium supplements or salt substitutes or other medicinal products that may increase serum potassium levels (e.g. heparin sodium) may lead to increases in serum potassium.
Maltese: L-użu konkomitanti ta' Atacand Plus u dijuretiċi li ma jneħħux il-potassju, supplimenti tal-potassju, sostituti tal-melħ li fihom il-potassju, jew prodotti mediċinali oħra li jistgħu jżidu l-livelli talpotassju (eż. heparin sodium) jistgħu jwasslu għal żidiet tal-potassju fis-serum.
English: These changes were considered to be caused by the pharmacological action of candesartan and to be of little clinical relevance.
Maltese: Dawn it-tibdiliet kienu kkunsidrati li ġew ikkawżati mill-azzjoni farmakoloġika ta' candesartan u huma ta' ftit relevanza klinika.
English: Thiazides have been shown to increase the urinary excretion of magnesium, which may result in hypomagnesaemia.
Maltese: Thiazides wrew li jżidu t-tneħħija ta' magnesium fl-awrina, li jista jirriżulta f' ipomagnesimija.
English: Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, diclofenac, celecoxib or etoricoxib (medicines to relieve pain and inflammation).
Maltese: • Mediċini anti-infjammatorji mhux sterojdi bħal ibuprofen, naproxen, diclofenac, celecoxib,
English: Concomitant treatment with cyclosporine may increase the risk of hyperuricaemia and gout-type complications.
Maltese: Kura konkomittanti ma cyclosporine jista jżid ir-riskju ta' iperuriċemija u kumplikazzjonijiet tip talgotta.
English: Anticholinergic agents (e.g. atropine, biperiden) may increase the bioavailability of thiazide-type diuretics by decreasing gastrointestinal motility and stomach emptying rate.
Maltese: Prodotti antikolinerġiċi (eż. atropine, biperiden) jistgħu jżidu l-bijodisponibilita' ta' dijuretiċi tat-tip thiazide billi jnaqqsu l-motilita gastrointestinali u r-rata ta' kemm jiżvojta l-istonku.
English: Your doctor may prescribe Atacand Plus if your blood pressure has not been properly controlled by candesartan cilexetil or hydrochlorothiazide alone.
Maltese: Xi ftit mill-effetti sekondarji ta' Atacand Plus huma ikkawżati minn candesartan cilexetil u xi ftit huma ikkawżati minn hdrochlorothiazide.
English: • Candesartan cilexetil belongs to a group of medicines called angiotensin II receptor antagonists.
Maltese: • Candesartan cilexetil jippartjeni lil grupp ta' mediċini li jissejħu antagonisti tar-riċettur angiotensin II. Jaħdem billi jirrilassa u jwessgħa il-kanali tad-demm.
English: Effects on the kidneys (such as regeneration, dilatation and basophilia in tubules; increased plasma concentrations of urea and creatinine) were induced by candesartan which could be secondary to the hypotensive effect leading to alterations of renal perfusion.
Maltese: Effetti fuq ilkliewi (bħal riġenerazzjoni, dilatazzjoni, tubuli bażofiliċi; żieda fil-konċentrazzjonijiet tal-urea u lkrejatinina fil-plażma) kienu kkaġunati minn candesartan li jistgħu jkunu ġejjin minħabba l-effett ta' pressjoni baxxa li jwassal għal tibdil fil-perfużjoni tal-kilwa.