FrancophonIA/ELRC3.0 huggingface dataset:
English: If you stop taking this medicine too quickly, you may have low blood pressure.
Croatian: Ako prestanete uzimati ovaj lijek prebrzo, možete dobiti niski krvni tlak.
English: Symptoms typically emerge within a few days or weeks of starting the treatment.
Croatian: Simptomi se obično pojavljuju u roku od nekoliko dana ili tjedana nakon početka liječenja.
English: Risk of infection
Croatian: Rizik od infekcije
English: If this is not the case, local or international treatment protocols and guidelines should be followed.
Croatian: Ako to nije primjenjivo, treba se pridržavati lokalnih ili međunarodnih protokola i smjernica za liječenje.
English: The efficacy of midazolam may be reduced.
Croatian: Djelotvornost midazolama može biti smanjena.
English: You may experience serious side effects if you stop taking this medicine suddenly.
Croatian: Možete doživjeti ozbiljne nuspojave ako iznenadno prekinete uzimati ovaj lijek.
English: You and your partner must use appropriate contraception.
Croatian: Vi i Vaš partner morate koristiti odgovarajuću kontracepciju (zaštitu).
English: Throw away half tablets that you have not taken.
Croatian: Bacite polovice tableta koje niste iskoristili.
English: No antidote exists and treatment is symptomatic.
Croatian: Ne postoji protuotrov a liječenje je simptomatično.
English: Before the start of treatment, any source of infection, especially tuberculosis, should be removed.
Croatian: Prije početka terapije potrebno je ukloniti svaki izvor infekcije, posebice tuberkuloze.
English: - if you are more than 12 hours late: do not take the tablet but take the next tablet at the usual time.
Croatian: - kasnite više od 12 sati: nemojte uzeti tabletu već uzmite sljedeću tabletu u uobičajeno vrijeme.
English: Your doctor will decide the dose and tell you on which days you should take it.
Croatian: Vaš će liječnik donijeti odluku o dozi lijeka i reći vam u koje dane je morate uzeti.
English: Your doctor will arrange appropriate blood tests before and during treatment.
Croatian: Vaš liječnik će dogovoriti odgovarajuće nalaze krvi prije i tijekom liječenja.
English: Uncontrolled psychoses.
Croatian: Nekontrolirane psihoze.
English: Genotoxicity findings have been shown to be artefactual.
Croatian: Nalazi genotoksičnosti dokazali su se artefaktualnim.
English: During treatment with this medicine it is important to maintain a balanced diet.
Croatian: Tijekom liječenja ovim lijekom, izuzetno je važno da održavate uravnoteženu prehranu.
English: Long-term treatment
Croatian: Dugoročno liječenje
English: Most reactions recover after either dose reduction or withdrawal, although specific treatment may be necessary.
Croatian: Većina se reakcija povuče nakon smanjivanja ili ustezanja doze, iako specifično liječenje može biti potrebno.
English: − if you have an untreated psychiatric illness.
Croatian: − ako imate neliječenu psihijatrijsku bolest.
English: Inform your doctor immediately if you are pregnant or if you become pregnant during treatment.
Croatian: Odmah obavijestite svog liječnika ako ste trudni ili ste zatrudnjeli tijekom liječenja.
English: These would include depressive or manic-depressive illness and previous steroid psychoses.
Croatian: To uključuje depresivne ili manično depresivne bolesti i ranije steroidne psihoze.
English: Your doctor will discuss these with you and will explain the potential risks and benefits of your treatment.
Croatian: Vaš će liječnik razgovarati s Vama o ovim nuspojava i objasnit će Vam moguće rizike i koristi liječenja.
English: Data on female fertility are contradictory.
Croatian: Podaci o plodnosti u žena su kontradiktorni.
English: Women of childbearing potential and their male partners should take appropriate contraceptive measures.
Croatian: Žene reproduktivne dobi i njihovi muški partneri trebaju poduzeti odgovarajuće kontracepcijske mjere.
English: 30 to 40% are conjugated to glucuronic acid or sulphated in the human liver and excreted in this form in the urine.
Croatian: 30 do 40% su konjugirani u glukuronsku kiselinu ili podvrgnuti sulfataciji u ljudskoj jetri te, u ovom obliku, izlučeni u urinu.
English: Patients should be advised to promptly report febrile episodes.
Croatian: Bolesnicima se treba savjetovati da odmah prijave febrilne epizode.
English: Frequencies are defined as: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000 including isolated reports), not known (cannot be estimated from the available data).
Croatian: Učestalosti se definiraju kao: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: The treatments with the two medicinal products should be separated by at least one week.
Croatian: Liječenja s dva lijeka moraju se provodi s razmakom od najmanje jednog tjedna.
English: You must take this medicine on the appropriate days, exactly as your doctor prescribed.
Croatian: Morate uzimati ovaj lijek na predviđene dane, točno kako je Vaš liječnik propisao.
English: Other possible side effects may be:
Croatian: Druge moguće nuspojave uključuju:
English: 17, Parc des Vautes 34980 Saint Gély du Fesc France
Croatian: 17, Parc des Vautes 34980 Saint Gély du Fesc Francuska
English: If you are over 65 years old and/or frail, your doctor may prescribe a half tablet each time.
Croatian: Ako ste stariji od 65 godina i/ili slaboga zdravlja, liječnik Vam može propisati i pola tablete po primjeni.
English: At high doses (e.g. 40 mg), it reduces the immune response.
Croatian: Pri visokim dozama (primjerice 40 mg) smanjuje imunološki odgovor.
English: If you forget to take Neofordex If you forget to take Neofordex at the usual time and - if you are less than 12 hours late: take the tablet immediately.
Croatian: Ako ste zaboravili uzeti lijek Neofordex Ako ste zaboravili uzeti Neofordex u uobičajeno vrijeme i - kasnite manje od 12 sati: odmah uzmite tabletu.
English: Effective measures to avoid pregnancy must be taken (see section 4.6).
Croatian: Moraju se poduzeti učinkovite mjere za izbjegavanje trudnoće (vidjeti dio 4.6).
English: There is a linear relationship between administered and bioavailable doses.
Croatian: Postoji linearan odnos između primijenjenih i bioraspoloživih doza.
English: Common: Cushing's syndrome;
Croatian: Često: Cushingov sindrom;
English: − Infection, inflammation of the whole body due to infection (sepsis);
Croatian: − Infekcija, upala cijelog tijela zbog infekcije (sepsa);
English: It the combination is required, monitoring should be reinforced and coagulation parameters controlled after one week and then every other week of treatment as well as after the end of treatment.
Croatian: Ako je kombinacija potrebna, praćenje se treba intenzivirati a parametre koagulacije treba kontrolirati nakon tjedan dana, te zatim svaki drugi tjedan liječenja kao i po završetku liječenja.
English: If you have difficulties taking the tablet out of the blister or breaking the tablet, ask somebody for help.
Croatian: Ako imate poteškoća s vađenjem tableta iz blistera ili lomljenjem tablete, zamolite nekoga za pomoć.
English: You doctor will observe you more closely if you have any of the listed diseases.
Croatian: Vaš liječnik će Vas pažljivije pratiti ako bolujete od bilo koje navedene bolesti.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Croatian: Zahtjevi za podnošenje periodičkih izvješća o neškodljivosti za ovaj lijek definirani su u referentnom popisu datuma EU (EURD popis) predviđenim člankom 107(c) stavkom 7 Direktive 2001/83/EZ i svakim svim sljedećim nadopunama objavljenim na europskom internetskom portalu za lijekove.
English: Infections and Infestations
Croatian: Infekcije i infestacije
English: Talk to your doctor before taking Neofordex if you or a member of your immediate family have suffered, or currently suffer from severe depression or manic attacks.
Croatian: Razgovarajte sa svojim liječnikom prije primjene lijeka Neofordex ako ste Vi ili član Vaše neposredne obitelji bolovali ili trenutno bolujete od teške depresije ili maničnih napadaja.
English: Swallow the prescribed dose of one tablet (40 mg) or half a tablet (20 mg) in the morning with a glass of water.
Croatian: Progutajte propisanu dozu od jedne tablete (40 mg) ili pola tablete (20 mg) ujutro s čašom vode.
English: Neofordex may cause serious mental health problems.
Croatian: Neofordex može uzrokovati ozbiljne mentalne zdravstvene probleme.
English: Then, keep the spare half tablet in a safe place, out of the sight and reach of children, until you can throw it away properly, as you should not throw away any medicines in wastewater or household waste.
Croatian: Međutim, čuvajte preostalu polovicu tablete na sigurnom mjestu, daleko od pogleda i dohvata djece, sve dok je ne budete mogli ispravno zbrinuti jer se nikakvi lijekovi ne smiju bacati u otpadne vode niti u kućni otpad.
English: It can also affect the nitro blue tetrazolium (NBT) test for bacterial infections and cause false-negative results.
Croatian: Također može utjecati na nitro blue tetrazoinum test (NBT) na bakterijske infekcije te uzrokovati lažno negativne rezultate.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Croatian: Ako ste trudni ili dojite, mislite da biste mogli biti trudni ili planirate imati dijete, obratite se svom liječniku ili ljekarniku za savjet prije nego uzmete ovaj lijeka.
English: The following combinations should be avoided due to safety concerns:
Croatian: Sljedeće se kombinacije trebaju izbjegavati zbog sigurnosnih razloga:
English: The benefit from dexamethasone treatment should be carefully and continuously weighed against actual and potential risks.
Croatian: Koristi od liječenja deksametazonom trebaju se pažljivo i kontinuirano odmjeravati u odnosu na stvarne i potencijalne rizike.
English: Multiple myeloma is a progressive rare haematologic disease.
Croatian: Multipli mijelom je progresivna rijetka hematološka bolest.
English: They act together by killing cancerous white blood cells.
Croatian: Ovi lijekovi djeluju zajedno tako što ubijaju kancerogene bijele krvne stanice.
English: Sodium intake should be reduced and blood pressure should be monitored.
Croatian: Unos natrija se mora smanjiti, a krvni se tlak mora pratiti.
English: There is a risk of severe strongyloidiasis.
Croatian: Postoji rizik od ozbiljne strongiloidijaze.
English: Your doctor may change the dose and frequency of administration based on certain parameters including your blood analyses, your general condition, other medicines prescribed to you and your response to the treatment.
Croatian: Vaš liječnik može promijeniti dozu i učestalost primjene na temelju određenih parametara uključujući analize krvi, Vašeg općeg stanja, drugih lijekova koji su Vam propisani i Vašeg odgovora na liječenje.
English: − Lack of body water (dehydration) with thirst or headache;
Croatian: Nedostatak tjelesne vode (dehidracija) povezan sa žeđi ili glavoboljom;
English: No differences were found in dexamethasone pharmacokinetics between subjects of European and Asian (Indonesian and Japanese) descent.
Croatian: Nisu utvrđene razlike u farmakokinetici deksametazona između osoba europskog i azijskog (indonezijskog i japanskog) porijekla.
English: The incidence rate of certain adverse reactions varies depending on the combination treatment used.
Croatian: Stopa incidencije određenih nuspojava varira ovisno o kombiniranom liječenju koje se koristi.
English: Such infections can also be caused by microorganisms that rarely cause disease under normal circumstances (opportunistic infections).
Croatian: Takve infekcije mogu također uzrokovati mikroorganizmi koji rijetko uzrokuju bolest u normalnim okolnostima (oportunistične infekcije).
English: If you need tests (in particular for infections) you should inform the person performing the tests as dexamethasone may interfere with the results.
Croatian: Ako su Vam potrebna testiranja (posebice na infekcije), morate o istome obavijestiti osobu koja provodi testove jer deksametazon može utjecati na rezultate.
English: • With anti-hypertensive medicinal products, due to a reduction of their effect (water and sodium retention).
Croatian: • s antihipertenzivnim lijekovima, zbog smanjivanja njihovog djelovanja (zadržavanje vode i natrija).
English: Do not exceed or take less than the prescribed dose.
Croatian: Ne premašujte propisanu dozu i ne uzimajte manju količinu od propisane doze.
English: Glucocorticoids are excreted in human milk and effects have been shown in breastfed newborns/infants of treated women.
Croatian: Glukokortikoidi se izlučuju u ljudskom mlijeku a njihov učinak je dokazan u dojene novorođenčadi/djece liječenih žena.
English: Action should be taken to try to minimize all modifiable risk factors (e.g. smoking, hypertension, and hyperlipidaemia).
Croatian: Potrebno je poduzeti radnje kako bi se pokušalo minimizirati sve modificirajuće faktore rizika (primjerice pušenje, hipertenziju i hiperlipidemiju).
English: Ask your pharmacist how to throw them away.
Croatian: Pitajte svog ljekarnika kako baciti tablete.
English: At very high doses the majority of dexamethasone circulates unbound in the blood.
Croatian: U slučaju vrlo jakih doza većina deksametazona cirkulira nevezana u krvi.
English: In order to minimise insomnia, the tablet should preferably be taken in the morning.
Croatian: Kako bi se smanjili izgledi za nesanicu, preporučuje se uzimanje tableta ujutro.
English: This should be taken into consideration in the surveillance of the patient.
Croatian: To treba imati na umu prilikom praćenja bolesnika.
English: If your treatment is to be stopped follow your doctor's advice.
Croatian: Ako se terapija mora prekinuti, pridržavajte se savjeta liječnika.
English: Risks may be higher with high doses (see also section 4.5 for pharmacokinetic interactions that can increase the risk of adverse reactions), although dose levels do not allow prediction of the onset, type severity or duration of reactions.
Croatian: Rizici mogu biti veći s većim dozama (vidjeti također dio 4.5 za farmakokinetičke interakcije koje mogu povećati rizik od nuspojava), iako razine doza ne dozvoljavaju predviđanja o nastupanju, ozbiljnosti tipa ili trajanju reakcija.
English: Excipient with known effect: Each tablet contains 98.1 mg lactose (as monohydrate).
Croatian: Pomoćna tvar s poznatim učinkom: Svaka tableta sadrži 98,1 mg laktoze (u obliku hidrata).
English: Treatment for active gastric or duodenal ulceration should be commenced prior to initiation of corticosteroids.
Croatian: Liječenje aktivne gastrične ili duodenalne ulceracije treba započeti prije početka terapije kortikosteroidima.
English: − if you are allergic to dexamethasone or one of the other ingredients of this medicine (listed in section 6),
Croatian: − ako ste alergični na deksametazon ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: Specific groups of patients
Croatian: Specifične grupe bolesnika
English: A dose reduction of lenalidomide or pomalidomide may be required.
Croatian: Može biti potrebno smanjenje doze lenalidomida ili pomalidomida.
English: You must not breast-feed during treatment.
Croatian: Tijekom liječenja ne smijete dojiti.
English: No chronic toxicity and carcinogenicity data are available.
Croatian: Nema dostupnih podataka o kroničnoj toksičnosti i karcinogenosti.
English: In some cases, the combination of several medicines can increase the side effects of one or the other of these medicines taken separately.
Croatian: U pojedinim slučajevima, kombinacija nekoliko lijekova može povećati nuspojave jednog ili drugog lijeka kada se uzima zasebno.
English: If you become ill or are involved in an accident, or if you need surgery (even at the dentist) or require a vaccination (particularly “live virus” vaccines) you should inform the doctor treating you that you are taking or have recently taken high-dose corticosteroids.
Croatian: Ako se razbolite ili budete uključeni u nesreću, ili Vam je potreban kirurški zahvat (čak i kod zubara) ili Vam je potrebno cjepivo (posebno cjepiva sa „živim virusom”), morate obavijestiti svog liječnika koji Vas liječi da uzimate ili da ste nedavno uzimali snažne doze kortikosteroida.
English: Common: Liver function tests abnormal, alanine aminotransferase increased.
Croatian: Često: abnormalni testovi funkcije jetre, povišena alanin aminotransferaza.
English: The tablet can be divided into two equal halves.
Croatian: Tableta se može podijeliti na dvije jednake polovice.
English: − Inability of the heart to pump enough blood round the body (heart failure);
Croatian: Nemogućnost srca da pumpa dovoljnu količinu krvi u tijelu (zatajenje srca);
English: Dexamethasone is bound by plasma proteins, principally albumin, up to about 80%, depending on the administered dose.
Croatian: Deksametazon vežu proteini u plazmi, i to prvenstveno albumin, do otprilike 80%, ovisno o primijenjenoj dozi.
English: High-dose corticosteroids, including dexamethasone, can cause psychological problems that may sometimes be serious.
Croatian: Snažne doze kortikosteroida, uključujući deksametazon, mogu uzrokovati psihološke probleme koji su ponekad ozbiljni.
English: If you have had blood clots in the past you should inform your doctor before taking Neofordex.
Croatian: Ako ste imali krvne ugruške u prošlosti, o tome morate obavijestiti svojeg liječnika prije nego što počnete uzimati Neofordex.
English: Patients/carers should also be alert to possible psychiatric disturbances that may occur either during, or immediately after, dose tapering/withdrawal of systemic steroids, although such reactions have been reported infrequently.
Croatian: Potrebno je upozoriti bolesnike/skrbnike na moguće psihijatrijske poremećaje koji mogu nastupiti tijekom ili neposredno nakon smanjivanja/ustezanja doze sistemskih steroida, iako takve reakcije nisu često prijavljivane.
English: Glucocorticoids have only weak acute toxicity.
Croatian: Glukokortikoidi imaju samo slabu akutnu toksičnost.
English: • Oral contraceptives, as it cannot be excluded that the efficacy of oral contraceptives may be reduced during treatment.
Croatian: • oralnih kontraceptiva, budući da se ne može isključiti mogućnost smanjivanja djelotvornosti oralnih kontracpetiva tijekom liječenja.
English: Neofordex should not be taken if you are pregnant unless clearly indicated by your doctor.
Croatian: Neofordex se ne smije uzimati ako ste trudni osim ako Vaš liječnik nije to jasno naznačio.
English: In case of active infectious disease, appropriate antiinfective treatment must be added to the treatment with Neofordex.
Croatian: U slučaju aktivne infektivne bolesti, odgovarajuće protuinfektivno liječenje mora se dodati liječenju lijekom Neofordex.
English: Halved tablets that are not taken immediately should be disposed of (see section 6.6).
Croatian: Prepolovljene tablete koje se ne uzmu odmah moraju se zbrinuti (vidjeti dio 6.6).
English: Prolonged exposure was required to achieve maximum levels of apoptotic markers along with increased caspase-3 activation and DNA fragmentation.
Croatian: Produljeno izlaganje bilo je potrebno kako bi se postigle maksimalne razine apoptotskih markera zajedno s povećanom aktivacijom kaspaze-3 i fragmentacijom DNK.
English: A haemoglobin concentration above 12 g/dl should lead to discontinuation of erythropoietic medicinal products.
Croatian: Koncentracija hemoglobina veća od 12 g/dl treba rezultirati prekidom primjene eritropoetskih lijekova.
English: − Failure of the thyroid gland to produce normal amounts of hormones (hypothyroidism);
Croatian: Nemogućnost štitnjače da stvara normalne količine hormona (hipotiroidizam);
English: Neofordex has moderate influence on the ability to drive and use machines.
Croatian: Neofordex umjereno utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Do not save the spare half tablet to take on another day as this medicine may deteriorate once divided and taken out of its packaging.
Croatian: Ne spremajte preostalu polovicu tablete kako biste ju uzeli drugi dan jer ovaj lijek može propasti nakon što je tableta jednom prepolovljena i izvađena iz pakiranja.
English: The following combinations require precautions due to changes in dexamethasone pharmacokinetics:
Croatian: Sljedeće kombinacije zahtijevaju mjere opreza zbog promjena u farmakokinetici deksametazona:
English: neofordex UNIQUE IDENTIFIER - 2D BARCODE
Croatian: JEDINSTVENI IDENTIFIKATOR - 2D BARKOD
English: Due to possible stability issues affecting half tablets stored after division, half-tablets that are not taken immediately should be discarded in agreement with local precautions for environmental protection (see also 6.4).
Croatian: Zbog mogućnosti da se poremeti stabilnost polovica tableta ako se one pohrane nakon razlamanja, polovice tableta koje se ne uzmu odmah moraju se zbrinuti u skladu s lokalnim propisima za zaštitu okoliša (vidi također 6.4).
English: Potassium levels should be monitored and corrected as necessary.
Croatian: Razine kalija treba pratiti i ispraviti prema potrebi.
English: This risk is increased by treatment with certain antibiotics and by kidney problems.
Croatian: Ovaj se rizik povećava liječenjem određenim antibioticima i problemima s bubrezima.
English: If you are using a pill organiser box, use the perforation to separate individual tablets from the blister without opening the packaging.
Croatian: Ako koristite organizator za lijekove, koristite se perforacijom kako biste odvojili pojedinačne tablete s blistera bez otvaranja pakiranja.
English: − Increased need for diabetes medicine, salt imbalance, potassium loss due to low carbon dioxide levels (a condition called metabolic alkalosis);
Croatian: Povećana potreba za lijekovima protiv dijabetesa, neravnoteža soli, gubitak kalija zbog malih razina ugljikovog dioksida (stanja nazvanog metabolička alkaloza);
English: Efficacy of hormone replacement therapy may also be reduced.
Croatian: Može doći i do smanjenja djelotvornosti hormonske zamjenske terapije.
English: Certain viral diseases (varicella, measles) can be aggravated in patients receiving glucocorticoid treatment or who have received glucocorticoid treatment within the previous 3 months.
Croatian: Određene virusne bolesti (varicela, ospice) mogu se pogoršati u bolesnika koji primaju liječenje glukokortikoidom ili koji su primili liječenje glukokortikoidom tijekom prethodna 3 mjeseca.
English: In elderly and/or frail patients, the daily dose may be reduced to 20 mg of dexamethasone, according to the appropriate treatment regimen.
Croatian: Dnevna se doza može, u starijih i/ili krhkih bolesnika, smanjiti na 20 mg deksametazona, u skladu s primjerenim režimom liječenja.
English: In cases of prior tuberculosis with major radiological sequelae or if it is not certain that a full 6-month rifampicin treatment course has been followed, a prophylactic anti-tuberculosis treatment is required.
Croatian: U slučaju ranije tuberkuloze sa značajnim radiološkim posljedicama ili ako nije sigurno je li završena cijela kura 6-mjesečnog liječenja rifampicinom, potrebno je provesti profilaktično liječenje protiv tuberkuloze.
English: Smoking has no influence on dexamethasone pharmacokinetics.
Croatian: Pušenje nema utjecaja na farmakokinetiku deksametazona.
English: Water and sodium retention is common and can lead to hypertension.
Croatian: Uobičajeno je zadržavanje vode i natrija, te može rezultirati hipertenzijom.
English: Not known: Infection, sepsis.
Croatian: Nepoznato: infekcija, sepsa.
English: Pack size of 10 tablets.
Croatian: Veličina pakiranja od 10 tableta.
English: If you notice blurring or distorted vision that lasts for several days, please contact your doctor.
Croatian: Ako primijetite da vam je vid zamućen ili iskrivljen nekoliko dana, molimo obratite se svojem liječniku.