FrancophonIA/ELRC3.0 huggingface dataset:
English: The median duration of therapy in the published literature ranged between 4 weeks and more than 20 months.
Slovenian: Mediano trajanje zdravljenja v objavljeni literaturi se je gibalo od 4 tednov do več kot 20 mesecev.
English: The first 37 patients were started at 400 mg, the protocol was subsequently amended to allow higher dosing and the remaining 223 patients were started at 600 mg.
Slovenian: Prvih 37 bolnikov je začelo zdravljenje s 400 mg, protokol je bil pozneje dopolnjen, tako da je omogočal večje odmerjanje, tako da je preostalih 223 bolnikov začelo zdravljenje s 600 mg.
English: Imatinib should not be used during pregnancy unless clearly necessary.
Slovenian: Imatiniba ne smete uporabljati pri nosečnicah, razen če je nujno potrebno.
English: Lymphoid blast crisis: a limited number of patients were enrolled in phase I studies (n = 10).
Slovenian: Limfoidna blastna kriza: Omejeno število bolnikov so vključili v študije prve faze (n = 10).
English: The decreases in white blood cell (WBC) and neutrophil counts occurred mainly during the first six weeks of therapy, with values remaining relatively stable thereafter.
Slovenian: Do znižanja števila belih krvnih celic in nevtrofilcev je prišlo večinoma v prvih šestih tednih zdravljenja, po tem obdobju pa so bile vrednosti relativno stabilne.
English: In this study, 31 % of patients achieved a haematological response (36 % in previously untreated patients and 22 % in previously treated patients).
Slovenian: V tej študiji je 31 % bolnikov doseglo hematološki odziv (36 % pri predhodno nezdravljenih bolnikih in 22 % pri predhodno zdravljenih bolnikih).
English: Events that have been reported at different dose ranges are as follows:
Slovenian: V različnih obsegih odmerkov so poročali o naslednjih dogodkih:
English: An unexpected rapid weight gain should be carefully investigated and if necessary appropriate supportive care and therapeutic measures should be undertaken.
Slovenian: Nepričakovano hitro naraščanje telesne mase je treba skrbno raziskati in izvajati ustrezne podporne in terapevtske ukrepe, če je potrebno.
English: As reported in a recent publication 21 of these 65 patients also achieved complete molecular remission with a median follow-up of 28 months (range 13-67 months).
Slovenian: Kot so nedavno objavili, je 21 od teh 65 bolnikov doseglo tudi popolno molekularno remisijo po mediano 28 mesecih spremljanja (razpon 13-67 mesecev).
English: Dose adjustment for adverse reactions in all indications in adults and paediatric patients
Slovenian: Prilagoditev odmerjanja zaradi neželenih učinkov pri vseh indikacijah pri odraslih in pediatričnih bolnikih
English: Women of childbearing potential Women of childbearing potential must be advised to use effective contraception during treatment.
Slovenian: Ženske v rodni dobi Ženskam v rodni dobi je treba svetovati, naj med zdravljenjem uporabljajo učinkovito kontracepcijo.
English: A major response combines both complete and partial responses: complete (0 % Ph+ metaphases), partial (1-35 %)
Slovenian: Pomemben odziv združuje tako popolne kot delne odzive: popoln (0 % Ph+ metafaz), delen (1
English: Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription (such as paracetamol) and including herbal medicines (such as St. John's Wort).
Slovenian: Obvestite zdravnika, farmacevta ali medicinsko sestro, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo, tudi če ste ga dobili brez recepta (na primer paracetamol), vključno z zdravili rastlinskega izvora (na primer šentjanževko).
English: Study 0102 38-month data Myeloid blast crisis (n = 260) % of patients (CI95 %)
Slovenian: Študija 0102 podatki pri 38 mesecih mieloidna blastna kriza (n = 260) % bolnikov (IZ95 %)
English: Safety data from this study seem to be in line with the safety profile of imatinib in Ph+ ALL patients.
Slovenian: Kaže, da se podatki o varnosti iz te študije ujemajo z varnostnim profilom imatiniba pri bolnikih s Ph+ ALL.
English: (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data).
Slovenian: Kategorije pogostnosti so opredeljene z naslednjim dogovorom: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: *, interstitial lung disease*
Slovenian: *, intersticijska pljučna bolezen*
English: Some children and adolescents taking Imatinib medac may have slower than normal growth.
Slovenian: Pri nekaterih otrocih in mladostnikih, ki jemljejo zdravilo Imatinib medac, je lahko rast počasnejša od normalne.
English: Clinical studies in MDS/MPD
Slovenian: Klinične študije pri MDS/MPD
English: The most important changes included cardiac hypertrophy and dilatation, leading to signs of cardiac insufficiency in some animals.
Slovenian: Najbolj pomembne spremembe vključujejo hipertrofijo in dilatacijo srca, ki povzročata znake srčnega popuščanja pri nekaterih živalih.
English: The preclinical safety profile of imatinib was assessed in rats, dogs, monkeys and rabbits.
Slovenian: Predklinični varnostni profil imatiniba je bil ocenjen pri podganah, psih, opicah in kuncih.
English: After correcting for the BSA effect, other demographics such as age, body weight and body mass index did not have clinically significant effects on the exposure of imatinib.
Slovenian: Po korekciji zaradi telesne površine drugi demografski dejavniki, kot so starost, telesna masa in indeks telesne mase, niso klinično pomembno vplivali na izpostavljenost imatinibu.
English: • Dry mouth, dry skin or dry eye.
Slovenian: • suha usta, suha koža ali suhe oči,
English: Clinical studies in Ph+ ALL
Slovenian: Klinične študije pri Ph+ ALL
English: The safety and efficacy of imatinib in children with MDS/MPD, DFSP and HES/CEL aged less than 18 years of age have not been established in clinical trials.
Slovenian: Varnost in učinkovitost imatiniba pri otrocih z MDS/MPD, DFSP in HES/CEL, starih manj kot 18 let, v kliničnih preskušanjih nista bili dokazani.
English: Pharmacotherapeutic group: protein kinase inhibitor, ATC code: L01XE01
Slovenian: Farmakoterapevtska skupina: zaviralec proteinskih kinaz, oznaka ATC: L01XE01
English: No histopathological changes were seen in rat liver.
Slovenian: V podganjih jetrih niso opazili histopatoloških sprememb.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in theagreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Slovenian: Imetnik dovoljenja za promet z zdravilom bo izvedel zahtevane farmakovigilančne aktivnosti in ukrepe, podrobno opisane v sprejetem RMP, predloženem v modulu 1.8.2 dovoljenja za promet z zdravilom, in vseh nadaljnjih sprejetih posodobitvah RMP.
English: Treatment with imatinib may then be continued at a reduced daily dose.
Slovenian: Nato se lahko zdravljenje z imatinibom nadaljuje z zmanjšanim dnevnim odmerkom.
English: In a recent publication updated information from 6 of these 11 patients revealed that all these patients remained in cytogenetic remission (range 32 - 38 months).
Slovenian: Nedavno objavljeni dopolnjeni podatki za 6 od teh 11 bolnikov razkrivajo, da so vsi ti bolniki ostali v citogenetični remisiji (po 32 - 38 mesecih).
English: Poland medac
Slovenian: Poljska medac
English: At the same dose, the number of stillborn pups as well as those dying between postpartum days 0 and 4 was increased.
Slovenian: Pri enakem odmerku se je povečalo število mrtvorojenih mladičev in tistih, ki so poginili med dnevoma 0 in 4 po skotitvi.
English: However, these oedemas were rarely severe and may be managed with diuretics, other supportive measures, or by reducing the dose of imatinib.
Slovenian: Vendar so bili ti edemi redko težki in jih lahko zdravimo z diuretiki, drugimi podpornimi ukrepi ali z zmanjšanjem odmerka imatiniba.
English: One of these intermediates was also positive in the mouse lymphoma assay.
Slovenian: Eden od teh vmesnih produktov je bil pozitiven tudi v testu mišjega limfoma.
English: Complete cytogenetic response confirmed by a second bone marrow cytogenetic evaluation performed at least one month after the initial bone marrow study.
Slovenian: Popoln citogenetični odziv, potrjen z drugo citogenetično oceno kostnega mozga, opravljeno vsaj en mesec po prvi študiji kostnega mozga.
English: However, some of these reactions may be serious or lifethreatening and several patients with blast crisis died with a complex clinical history of pleural effusion, congestive heart failure and renal failure.
Slovenian: Vendar so nekatere od teh reakcij lahko resne ali smrtno nevarne.Več bolnikov z blastno krizo je namreč umrlo z zapleteno klinično anamnezo plevralnega izliva, kongestivnega popuščanja srca in ledvične odpovedi.
English: Check whether cytopenia is related to leukaemia (marrow aspirate or biopsy).
Slovenian: Preverite, ali je citopenija povezana z levkemijo (aspirat ali biopsija kostnega mozga).
English: Studies in animals have however shown reproductive toxicity (see section 5.3) and the potential risk for the foetus is unknown.
Slovenian: Študije na živalih so pokazale vpliv na sposobnost razmnoževanja (glejte poglavje 5.3) in možno tveganje za plod ni znano.
English: At the time of analysis, the median treatment duration was 47 months (24 days - 60 months).
Slovenian: V času analize je bilo mediano trajanje zdravljenja 47 mesecev (24 dni - 60 mesecev).
English: • Imatinib medac is not recommended during pregnancy unless clearly necessary as it may harm your baby.
Slovenian: • Uporaba zdravila Imatinib medac v nosečnosti ni priporočena, če to ni nujno potrebno, saj lahko škoduje vašemu otroku.
English: Therefore, the use of imatinib in combination with other chemotherapeutic agents requires special precaution.
Slovenian: Zato je pri uporabi imatiniba v kombinaciji z drugimi kemoterapevtiki potrebna posebna previdnost.
English: The results observed in a population of 211 newly diagnosed Ph+ ALL patients in four uncontrolled clinical studies (AAU02, ADE04, AJP01 and AUS01) are consistent with the results described above.
Slovenian: Pri populaciji 211 bolnikov z novo odkrito Ph+ ALL iz štirih nekontroliranih kliničnih študij (AAU02, ADE04, AJP01 in AUS01) se rezultati ujemajo z zgoraj opisanimi.
English: A further 6 DFSP patients treated with imatinib were reported in 5 published case reports, their ages ranging from 18 months to 49 years.
Slovenian: Nadaljnjih 6 bolnikov z DFSP, zdravljenih z imatinibom, so opisali v 5 publikacijah opisov primera, njihova starost se je gibala med 18 meseci in 49 leti.
English: In the event of overdose, the patient should be observed and appropriate supportive treatment given.
Slovenian: V primeru prevelikega odmerjanja je treba bolnika opazovati in mu nuditi ustrezno podporno zdravljenje.
English: • The other ingredients are crospovidone (type A), lactose monohydrate, magnesium stearate.
Slovenian: • Druge sestavine zdravila so krospovidon (tip A), laktoza monohidrat, magnezijev stearat.
English: Clinical studies in HES/CEL
Slovenian: Klinične študije pri HES/CEL
English: These events can usually be managed with either a reduction of the dose or an interruption of treatment with imatinib, but can in rare cases lead to permanent discontinuation of treatment.
Slovenian: Ti dogodki se lahko odpravljajo bodisi z zmanjšanjem odmerka bodisi z začasno prekinitvijo zdravljenja z imatinibom, v redkih primerih pa so lahko razlog za trajno prekinitev zdravljenja.
English: Studies in two breast-feeding women revealed that both imatinib and its active metabolite can be distributed into human milk.
Slovenian: Študije pri dveh doječih materah so pokazale, da se tako imatinib kot njegov aktivni presnovek pri človeku lahko izločata v materino mleko.
English: The complete molecular response rate was 48 % (49 out of 102 evaluable patients).
Slovenian: Delež bolnikov s popolnim molekularnim odzivom je bil 48 % (49 od 102 za oceno primernih bolnikov).
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2).
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja zdravila je na recept le s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: • Unexpected bleeding or bruising (when you have not hurt yourself).
Slovenian: • nepričakovana krvavitev ali modrica (ne da bi se prej poškodovali).
English: The effect of stopping treatment after the achievement of a complete cytogenetic response has not been investigated.
Slovenian: Učinek prekinitve zdravljenja po doseženem popolnem citogenetičnem odzivu ni raziskan.
English: There is limited experience in children and adolescents with Ph-positive ALL.
Slovenian: Izkušenj pri otrocih in mladostnikih s Ph-pozitivno ALL je malo.
English: These reactions can usually be managed by withholding imatinib temporarily and with diuretics and other appropriate supportive care measures.
Slovenian: Te reakcije lahko navadno zdravimo z začasno ukinitvijo imatiniba, z diuretiki in drugimi ustreznimi podpornimi negovalnimi ukrepi.
English: • Eye pain or deterioration in vision, bleeding in the eyes.
Slovenian: • bolečine v očeh ali poslabšanje vida, krvavitve v očeh,
English: Transformed CML is the stage of the disease after its progression from chronic phase to accelerated phase (AP) or blast crisis (BC).
Slovenian: Transformacija KML je stadij bolezni po napredovanju iz kronične faze v pospešeno fazo (AP) ali blastno krizo (BC).
English: GI and tumoural bleeding may be serious and sometimes fatal.
Slovenian: Krvavitve iz prebavil in tumorja so lahko resne in včasih življenje ogrožajoče.
English: Total bilirubin: = 1.5 ULN AST: >ULN (can be normal or < ULN if total bilirubin is >ULN)
Slovenian: AST: > ULN (lahko je normalna ali < ULN, če je celotni bilirubin >ULN)
English: Therapeutic indication
Slovenian: Terapevtska indikacija
English: The median duration of the neutropenic and thrombocytopenic episodes usually ranged from 2 to 3 weeks, and from 3 to 4 weeks, respectively.
Slovenian: Povprečno trajanje nevtropeničnih oziroma trombocitopeničnih epizod je bilo navadno 2-3 tedne oziroma 3-4 tedne.
English: Patients on imatinib treatment who are concerned about their fertility should consult with their physician.
Slovenian: Bolniki, ki se zdravijo z imatinibom in jih skrbi glede njihove plodnosti, naj se posvetujejo s svojim zdravnikom.
English: In the F1 offspring, at the same dose level, mean body weights were reduced from birth until terminal sacrifice and the number of litters achieving criterion for preputial separation was slightly decreased.
Slovenian: Pri potomcih F1 se je pri enakem odmerku povprečna telesna masa zmanjšala od skotitve do terminalnega žrtvovanja, število mladičev, ki so dosegli kriterij za ločitev prepucija, pa se je rahlo zmanjšalo.
English: Blast crisis is defined as blasts ≥ 30 % in blood or bone marrow or extramedullary disease other than hepatosplenomegaly.
Slovenian: Blastno krizo opredeljuje ≥ 30 % blastov v krvi ali kostnem mozgu ali ekstramedularna bolezen, ki ni hepatosplenomegalija.
English: 20 out of the 50 (40 %) patients in cohort 5 received haematopoietic stem cell transplant.
Slovenian: 20 od 50 bolnikov (40 %) v 5. kohorti so presadili krvotvorne matične celice.
English: • Women who might become pregnant are advised to use effective contraception during
Slovenian: • Ženskam, ki bi lahko zanosile, med zdravljenjem priporočamo uporabo učinkovite
English: Myeloid blast crisis: 260 patients with myeloid blast crisis were enrolled.
Slovenian: Mieloidna blastna kriza: Vključili so 260 bolnikov z mieloidno blastno krizo.
English: BATCH NUMBER Lot:
Slovenian: ŠTEVILKA SERIJE Lot
English: Reactivation of hepatitis B in patients who are chronic carriers of this virus has occurred after these patients received BCR-ABL tyrosine kinase inhibitors.
Slovenian: Reaktivacija hepatitisa B pri bolnikih, ki so kronični prenašalci tega virusa, se je pojavila, potem ko so ti bolniki prejeli zaviralce tirozinske kinaze BCR-ABL1.
English: In clinical trials in CML, discontinuation of the investigational medicinal product for treatment-related adverse reactions was observed in 2.4 % of newly diagnosed patients, 4 % of patients in late chronic phase after failure of interferon therapy, 4 % of patients in accelerated phase after failure of interferon therapy and 5 % of blast crisis patients after failure of interferon therapy.
Slovenian: V kliničnih preskušanjih pri KML so prekinitev dajanja raziskovanega zdravila zaradi neželenih učinkov, povezanih z zdravljenjem, zabeležili pri 2,4 % na novo diagnosticiranih bolnikov, 4 % bolnikov v pozni kronični fazi po neuspelem zdravljenju z interferonom, 4 % bolnikov v pospešeni fazi po neuspelem zdravljenju z interferonom in 5 % bolnikov v blastni krizi po neuspelem zdravljenju z interferonom.
English: The active substance imatinib demonstrates an environmental risk for sediment organisms.
Slovenian: Zdravilna učinkovina imatinib kaže okoljsko tveganje za sedimentne organizme.
English: If you take more Imatinib medac than you should If you have accidentally taken too many capsules, talk to your doctor straight away.
Slovenian: Če ste vzeli večji odmerek zdravila Imatinib medac, kot bi smeli Če ste pomotoma vzeli preveč kapsul, se nemudoma posvetujte s svojim zdravnikom.
English: • If you are a woman who is pregnant or might get pregnant and are trying to open the capsules for your children or another patient unable to swallow, you should handle the contents with caution in order to avoid skin-eye contact or inhalation.
Slovenian: • Če ste noseči ali bi lahko zanosili in odpirate kapsule za svoje otroke ali kakega drugega bolnika, ki ne more požirati, ravnajte pri odpiranju kapsule z vsebino pazljivo in se izogibajte stiku zdravila z očmi preko rok ali vdihavanju zdravila.
English: In study 0102 [ANC ≥ 1.5 x 10
Slovenian: V študiji 0102 [ANC ≥ 1,5 x 10
English: When female rats were dosed 14 days prior to mating and through to gestational day 6, there was no effect on mating or on number of pregnant females.
Slovenian: Ko so podganje samice dobivale zdravilo 14 dni pred parjenjem in nato ves čas do 6. dne brejosti, ni bilo nikakršnega učinka na parjenje ali na število brejih samic.
English: 8 g to 10 g (single dose): Vomiting and gastrointestinal pain have been reported.
Slovenian: Odmerki od 8 g do 10 g (enkratni odmerki): opisovali so bruhanje in bolečine v prebavilih.
English: The doctor will tell you how many capsules of Imatinib medac to give to your child.
Slovenian: Zdravnik vam bo povedal, koliko kapsul zdravila Imatinib medac dajte svojemu otroku.
English: While you are taking Imatinib medac, your doctor will regularly check whether the medicine is working.
Slovenian: Med jemanjem zdravila Imatinib medac bo zdravnik redno spremljal, ali zdravilo deluje.
English: They may increase or decrease the effect of Imatinib medac, either leading to increased side effects or making Imatinib medac less effective.
Slovenian: Lahko povečajo ali zmanjšajo učinek zdravila Imatinib medac in zato bodisi povečajo verjetnost za nastanek neželenih učinkov, bodisi zmanjšajo učinkovitost zdravila Imatinib medac.
English: Teratogenic effects included exencephaly or encephalocele, absent/reduced frontal and absent parietal bones.
Slovenian: Teratogeni učinki so obsegali eksencefalijo ali encefalokelo, odsotnost ali zmanjšanje frontalnih kosti ter odsotnost parietalnih kosti.
English: Accelerated phase is an intermediate phase among the chronic phase and the onset of the blast crisis; it is considered as the first manifestation of resistance to therapy.
Slovenian: Pospešena faza je vmesna faza med kronično fazo in nastopom blastne krize; velja za prvi znak odpornosti proti zdravljenju.
English: As expected on the basis of the study design, no difference was observed in remission duration, disease-free survival or overall survival, although patients with complete molecular response and remaining in minimal residual disease had a better outcome in terms of both remission duration (p = 0.01) and disease-free survival (p = 0.02).
Slovenian: Kot je bilo pričakovati glede na načrt študije, ni bilo nobene razlike v trajanju remisij, preživetju brez bolezni ali preživetju nasploh, čeprav so imeli bolniki s popolnim molekularnim odzivom in tisti z minimalno rezidualno boleznijo boljši izid glede trajanja remisije (p = 0,01) in preživetja brez bolezni (p = 0,02).
English: However, since the effects of low-dose exposure of the infant to imatinib are unknown, women taking imatinib should not breast-feed.
Slovenian: Vendar učinki izpostavljenosti dojenčka nizkim odmerkom imatiniba niso znani, zato ženske, ki jemljejo imatinib ne smejo dojiti.
English: Use in adults Your doctor will tell you exactly how many capsules of Imatinib medac to take.
Slovenian: Uporaba pri odraslih Zdravnik vam bo natančno povedal, koliko kapsul zdravila Imatinib medac morate jemati.
English: The effect of bodyweight on the clearance of imatinib is such that for a patient weighing 50 kg the mean clearance is expected to be 8.5 l/h, while for a patient weighing 100 kg the clearance will rise to 11.8 l/h.
Slovenian: Vpliv telesne mase na očistek imatiniba je takšen, da je pri bolniku, ki tehta 50 kg, pričakovani povprečni očistek 8,5 l/h, pri bolniku, ki tehta 100 kg, pa se očistek poveča na 11,8 l/h.
English: Posology modification
Slovenian: Sprememba odmerjanja
English: Cytogenetic response criteria:
Slovenian: Kriteriji citogenetičnega odziva:
English: Concomitant use of rifampicin or other strong CYP3A4 inducers and imatinib should be avoided.
Slovenian: Sočasni uporabi rifampicina ali drugih močnih induktorjev CYP3A4 in imatiniba se je treba izogibati.
English: The median time to progression in the overall population of 411 patients with relapsed/refractory Ph+ ALL ranged from 2.6 to 3.1 months, and median overall survival in the 401 evaluable patients ranged from 4.9 to 9 months.
Slovenian: Mediani čas do napredovanja bolezni je bil pri vseh 411 bolnikih z relapsom/neodzivno Ph+ ALL v obsegu od 2,6 do 3,1 meseca, mediano preživetje nasploh pa je bilo pri 401 za oceno primernih bolnikov v obsegu od 4,9 do 9 mesecev.
English: DFSP (at dose 800 mg)
Slovenian: DFSP (ob odmerku 800 mg)
English: Experience with imatinib in this indication is very limited and is based on haematological and cytogenetic response rates.
Slovenian: Za to indikacijo so izkušnje z imatinibom zelo omejene in temeljijo na hematološki in citogenetični odzivnosti.
English: The majority of patients who achieved a CCyR developed the CCyR between months 3 and 10 with a median time to response based on the Kaplan-Meier estimate of 5.6 months.
Slovenian: Večina bolnikov, ki je dosegla popolni citogenetični odziv, ga je dosegla med 3. in 10. mesecem z medianim časom do odziva 5,6 meseca glede na Kaplan-Meierjevo oceno.
English: 95 (37 %) had received prior chemotherapy for treatment of either accelerated phase or blast crisis (“pretreated patients”) whereas 165 (63 %) had not (“untreated patients”).
Slovenian: 95 bolnikov (37 %) je imelo predhodno kemoterapijo za zdravljenje bodisi pospešene faze bodisi blastne krize (»predhodno zdravljeni bolniki«), medtem ko 165 bolnikov (63 %) ni bilo predhodno zdravljenih (»nezdravljeni bolniki«).
English: Your doctor has prescribed Imatinib medac because you suffer from a serious condition.
Slovenian: Zdravnik vam je predpisal zdravilo Imatinib medac, ker imate resno bolezen.
English: Ara-C: cytosine arabinoside; CP: cyclophosphamide; DEX: dexamethasone; MTX: methotrexate; 6-MP: 6-mercaptopurine VM26: Teniposide; VCR: vincristine; IDA: idarubicine; i.v.
Slovenian: Ara-C: citozin arabinozid; CP: ciklofosfamid; DEX: deksametazon; MTX: metotreksat; 6-MP: 6-merkaptopurin; VM26: tenipozid; VCR: vinkristin; IDA: idarubicin; i.v.