FrancophonIA/ELRC3.0 huggingface dataset:
English: 3-Day Starterpack (Combined pack)
Croatian: SEROQUEL 3-dnevno početno pakiranje (kombinirano pakiranje)
English: Tell your doctor immediately if you experience any of the following after taking Seroquel::
Croatian: Odmah recite svome liječniku ako osjetite nešto od sljedećeg nakon uzimanja Seroquela:
English: Tell your doctor immediately if you experience any of the following after taking Seroquel XR:
Croatian: Odmah recite svome liječniku ako osjetite nešto od sljedećeg nakon uzimanja Seroquela XR:
English: If you stop taking Seroquel
Croatian: Ako prestanete uzimati Seroquel
English: Pharmacokinetic data were sampled in 9 children aged 10-12 years old and 12 adolescents, who were on steady-state treatment with 400 mg quetiapine twice daily.
Croatian: Farmakokinetički podaci dobiveni su na uzorku od devetero djece u dobi od 10-12 godina i 12 adolescenata, koji su bili u stanju dinamičke ravnoteže s 400 mg kvetiapina dva puta dnevno.
English: The class of medicines to which Seroquel XR belongs can cause heart rhythm problems, which can be serious and in severe cases may be fatal.
Croatian: Lijekovi iz skupine kojoj pripada i Seroquel XR, mogu uzrokovati poremećaje srčanoga ritma, koji mogu biti ozbiljni, a u teškim slučajevima i smrtonosni.
English: At steady-state, the dose-normalised plasma levels of the parent compound, quetiapine, in children and adolescents (10-17 years of age) were in general similar to adults, though Cmax in children was at the higher end of the range observed in adults.
Croatian: U stanju dinamičke ravnoteže, razina normaliziranog roditeljskog spoja u plazmi, kvetiapina, u djece i adolescenata (10-17 godina) uglavnom je bila slična onoj u odraslih, iako je Cmax u djece bio na gornjoj granici raspona zabilježenog u odraslih.
English: Seroquel data in combination with divalproex or lithium in acute moderate to severe manic episodes at 3 and 6 weeks is limited; however, combination therapy was well tolerated.
Croatian: Podaci o djelovanju Seroquela u kombinaciji s divalproeksom ili litijem u akutnom liječenju umjerenih do teških maničnih epizoda u trećem i šestom tjednu su ograničeni, premda je kombinirano liječenje bilo dobro podnošljivo.
English: Clinicians should therefore ensure that the lowest effective dose, starting with 50 mg/day, is used for treatment.
Croatian: Stoga kliničari trebaju koristiti za liječenje najnižu učinkovitu dozu, počevši od 50 mg/dan.
English: How to take Seroquel
Croatian: Kako uzimati Seroquel
English: Acute withdrawal symptoms such as insomnia, nausea, headache, diarrhoea, vomiting, dizziness, and irritability have been described after abrupt cessation of quetiapine.
Croatian: Akutni simptomi ustezanja koji uključuju nesanicu, mučninu, glavobolju, proljev, povraćanje, omaglicu i razdražljivost, opisani su nakon naglog prekida uzimanja kvetiapina.
English: • You have ever had a fit (seizure).
Croatian: • ako ste ikada imali napadaje.
English: Tablet coating: hypromellose, macrogol, titanium dioxide (E171).
Croatian: Ovojnica: hipromeloza, makrogol, titanijev dioksid (E 171).
English: No data is available about the incidence of seizures in patients with a history of seizure disorder.
Croatian: Nema dostupnih podataka o incidenciji napadaja kod bolesnika s anamnezom takvih poremećaja.
English: Due to lack of robust data, a decision must be made whether to discontinue breast-feeding or to discontinue Seroquel XR therapy taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Croatian: Zbog nedostatka robusnih podataka, odluku o tome hoće li se prekinuti dojenje ili terapija Seroquelom XR treba donijeti uzimajući u obzir koristi dojenja za dijete i koristi liječenja za ženu.
English: The same ADRs described above for adults should be considered for children and adolescents.
Croatian: Prethodno opisane nuspojave, koje su bile zabilježene u odraslih potrebno je uzeti u obzir i kod djece i adolescenata.
English: The efficacy of Seroquel XR in the treatment of schizophrenia was demonstrated in one 6-week placebocontrolled trial in patients who met DSM-IV criteria for schizophrenia, and one active-controlled Seroquel immediate release-to-Seroquel XR switching study in clinically stable outpatients with schizophrenia.
Croatian: Djelotvornost Seroquela XR u liječenju shizofrenije, pokazana je u jednom 6-tjednom, placebom kontroliranom ispitivanju, provedenom u bolesnika koji su udovoljavali DSM-IV (The Diagnostic and Statistical Manual of Mental Disorders) kriterijima za dijagnosticiranje shizofrenije, te u jednom aktivno kontroliranom ispitivanju koje se bavilo učincima prelaska klinički stabilnih, ambulantno liječenih bolesnika oboljelih od shizofrenije, sa Seroquel tableta s trenutnim oslobađanjem na Seroquel XR.
English: Extrapyramidal symptoms:
Croatian: Ekstrapiramidni simptomi:
English: Due to lack of robust data, a decision must be made whether to discontinue breast-feeding or to discontinue Seroquel therapy taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Croatian: Zbog nedostatka robusnih podataka, odluku o tome hoće li se prekinuti dojenje ili terapija Seroquelom treba donijeti uzimajući u obzir koristi dojenja za dijete i koristi liječenja za ženu.
English: • treatment of bipolar disorder: o For the treatment of moderate to severe manic episodes in bipolar disorder o For the treatment of major depressive episodes in bipolar disorder o For the prevention of recurrence of manic or depressed episodes in patients with bipolar disorder who previously responded to quetiapine treatment.
Croatian: • liječenje bipolarnog poremećaja: o za liječenje umjerenih do teških maničnih epizoda u bipolarnom poremećaju. o za liječenje velikih depresivnih epizoda u bipolarnom poremećaju. o za sprječavanje ponovne pojave maničnih ili depresivnih epizoda u bolesnika s bipolarnim poremećajem koji su prethodno odgovorili na liječenje kvetiapinom.
English: Your tablets may make you feel sleepy.
Croatian: Vas učiniti pospanima.
English: In a monotherapy relapse prevention study, patients with depressive episodes stabilised on open-label Seroquel XR treatment for at least 12 weeks were randomised to either Seroquel XR once daily or placebo for up to 52 weeks.
Croatian: U monoterapijskom ispitivanju otvorenog tipa za prevenciju relapsa, bolesnici s depresivnim epizodama stabilizirani na terapiji Seroquelom XR tijekom najmanje 12 tjedana bili su randomizirani u skupinu koja je uzimala Seroquel XR jednom dnevno, ili u skupinu koja je uzimala placebo, tijekom 52 tjedna.
English: Do not store above 30°C.
Croatian: POSEBNE MJERE ČUVANJA Ne čuvati na temperaturi iznad 30°C.
English: during their pregnancy
Croatian: Stanja vezana uz trudnoću,
English: The rates of suicide related events in the active arm vs. placebo were 1.4% vs. 1.3% in the schizophrenia trial, 1.0% vs. 0% in the bipolar mania trial, and 1.1% vs. 0% in the bipolar depression trial.
Croatian: Stope događaja povezanih sa samoubojstvom u aktivno liječenim skupinama u odnosu na skupine koje su primale placebo bile su sljedeće: 1,4% naspram 1,3% u ispitivanju u shizofreniji, 1,0% naspram 0% u ispitivanju u bipolarnoj maniji te 1,1% naspram 0% u ispitivanju u bipolarnoj depresiji.
English: Antidepressant effect was seen at 150 and 300 mg/day in shortterm trials as add-on therapy (with amitriptyline, bupropion, citalopram, duloxetine, escitalopram, fluoxetine, paroxetine, sertraline and venlafaxine - see Section 5.1) and at 50 mg/day in short-term monotherapy trials.
Croatian: Antidepresivni učinak je opažen pri 150 i 300 mg/dan u kratkoročnim kliničkim ispitivanjima kao dodatna terapija (sa amitriptilinom, bupropionom, citalopramom, duloksetinom, escitalopramom, fluoksetinom, paroksetinom, sertralinom i venlafaksinom - vidjeti dio 5.1), i pri 50
English: Tablet Strength
Croatian: Jačina tableta
English: Seroquel can be administered with or without food.
Croatian: Seroquel se uzima s hranom ili bez nje.
English: Clinical trials with quetiapine have shown that in addition to the known safety profile identified in adults (see section 4.8), certain adverse events occurred at a higher frequency in children and adolescents compared to adults (increased appetite, elevations in serum prolactin, vomiting, rhinitis and syncope), or may have different implications for children and adolescents (extrapyramidal symptoms and irritability) and one was identified that has not been previously seen in adult studies (increases in blood pressure).
Croatian: Klinička ispitivanja s kvetiapinom su dodatno pokazala, uz poznati sigurnosni profil lijeka u odraslih (vidjeti dio 4.8), da se određeni štetni događaji pojavljuju s većom učestalošću u djece i adolescenata nego u odraslih (povećani apetit, porast serumskog prolaktina, povraćanje, rinitis i sinkopa) ili mogu imati drugačije implikacije u djece i adolescenata (ekstrapiramidni simptomi i razdražljivost), a zabilježen je i jedan koji prethodno nije primijećen u ispitivanjima u odraslih (povišenje krvnog tlaka).
English: The pharmacokinetics of quetiapine were not significantly altered by co-administration of the antipsychotics risperidone or haloperidol.
Croatian: Farmakokinetika kvetiapina nije se znatnije promijenila kad se uzimao istodobno s antipsihoticima risperidonom ili haloperidolom.
English: Weight gain has been seen in patients taking Seroquel XR.
Croatian: Primijećeno je povećanje tjelesne težine kod bolesnika koji uzimaju Seroquel XR.
English: The mean plasma clearance of quetiapine was reduced by 30-50% in elderly subjects when compared to younger patients.
Croatian: Srednja vrijednost plazmatskog klirensa kvetiapina u starijih bolesnika smanjena je za 30-50% u usporedbi s mlađim bolesnicima.
English: The percentage of quetiapine treated patients who gained ≥7% of body weight ranged from 5.3% for the 50 mg daily dose to 15.5% for the 400 mg daily dose (with lower gain for the 600 and 800 mg daily doses), compared to 3.7% for placebo treated patients.
Croatian: Postotak bolesnika liječenih kvetiapinom koji su dobili ≥7% tjelesne težine varira od 5,3% za dnevnu dozu od 50 mg do 15,5% za dnevnu dozu od 400 mg (s nižim prirastom za dnevne doze od 600 i 800 mg), u usporedbi s 3,7% za bolesnike koji su primali placebo.
English: First trimester
Croatian: Prvo tromjesečje
English: Lipids:
Croatian: Lipidi:
English: What Seroquel XR looks like and contents of the pack
Croatian: Kako Seroquel XR izgleda i sadržaj pakiranja
English: The rates of weight gain ≥ 7% of baseline body weight in the active arm vs. placebo were 17% vs. 2.5% in the schizophrenia and bipolar mania trials, and 12.5% vs. 6% in the bipolar depression trial.
Croatian: Stope porasta tjelesne težine za ≥ 7% od početne vrijednosti tjelesne težine u aktivno liječenim skupinama u odnosu na skupine koje su primale placebo bile su sljedeće: 17% naspram 2,5% u ispitivanjima u shizofreniji i bipolarnoj maniji te 12,5% naspram 6% u ispitivanju u bipolarnoj depresiji.
English: In one long-term study (up to 2 years treatment) evaluating recurrence prevention in patients with manic, depressed or mixed mood episodes quetiapine was superior to placebo in increasing the time to recurrence of any mood event (manic, mixed or depressed), in patients with bipolar I disorder.
Croatian: U jednom dugoročnom ispitivanju (do dvije godine liječenja), u kojoj je evaluirano sprječavanje ponovne pojave u bolesnika s maničnim, depresivnim ili mješovitim epizodama, kvetiapin je bio superiorniji u odnosu na placebo u povećanju vremena do ponovne pojave bilo koje epizode poremećaja raspoloženja (manične, mješovite ili depresivne) kod bolesnika s bipolarnim poremećajem tipa I.
English: Decreases in free T3
Croatian: smanjenja razine ukupnog T3
English: These include difficulty starting muscle movements, shaking, feeling restless or muscle stiffness without pain.
Croatian: Oni uključuju otežano pokretanje mišića, tresavicu, osjećaj nemira ili ukočenost mišića bez boli.
English: QT Prolongation
Croatian: QT prolongacija
English: (YMRS improvement ≥50%) were 64% for Seroquel 400 mg/day, 58% for 600 mg/day and 37% in the placebo arm.
Croatian: poboljšanje ≥ 50%) bila je 64% za Seroquel 400 mg dnevno, 58% za 600 mg dnevno i 37% za placebo.
English: The class of medicines to which Seroquel belongs can cause heart rhythm problems, which can be serious and in severe cases may be fatal.
Croatian: Lijekovi iz skupine kojoj pripada i Seroquel mogu uzrokovati poremećaje srčanoga ritma, koji mogu biti ozbiljni, a u teškim slučajevima i smrtonosni.
English: Frequency based on adverse event reports of bradycardia and related events in all clinical trials with quetiapine.
Croatian: Učestalost se temelji na prijavama bradikardije i povezanih događaja u svim kliničkim ispitivanjima s kvetiapinom.
English: In open label trials, in patients with schizophrenia, quetiapine was effective in maintaining the clinical improvement during continuation therapy in patients who showed an initial treatment response, suggesting some long-term efficacy.
Croatian: U otvorenim ispitivanjima, u bolesnika sa shizofrenijom koji su prvobitno reagirali na liječenje, kvetiapin je bio učinkovit u održavanju kliničkog poboljšanja tijekom kontinuiranog liječenja, što sugerira dugotrajnu djelotvornost.
English: The pharmacokinetics of sodium valproate and quetiapine were not altered to a clinically relevant extent when co-administered.
Croatian: Farmakokinetika natrijeva valproata i kvetiapina nije se izmijenila u klinički značajnome opsegu kad su se istodobno primjenjivali.
English: Neither low dose (400 mg/day) nor high dose regimen (800 mg/day) quetiapine was superior to placebo with respect to the percentage of patients achieving response, defined as ≥30% reduction from baseline in PANSS total score.
Croatian: Niti niža doza (400 mg dnevno), niti viša doza (800 mg dnevno) kvetiapina nisu bile superiornije placebu uzimajući u obzir postotak bolesnika kod kojih je došlo do odgovora na liječenje, definiran kao ≥ 30%-tno smanjenje od početne vrijednosti ukupnog rezultata PANSS ljestvice.
English: • add-on treatment of major depressive episodes in patients with Major Depressive Disorder (MDD) who have had sub-optimal response to antidepressant monotherapy (see Section 5.1).
Croatian: (Major Depressive Disorder, MDD) koji su imali suboptimalni odgovor na monoterapiju antidepresivima (vidjeti dio 5.1).
English: Cellulose, microcrystalline Sodium citrate Lactose monohydrate Magnesium stearate Hypromellose 2208
Croatian: Jezgra celuloza, mikrokristalična natrijev citrat laktoza hidrat magnezijev stearat hipromeloza 2208
English: In a multiple dose trial in patients to assess the pharmacokinetics of quetiapine given before and during treatment with carbamazepine (a known hepatic enzyme inducer), co-administration of carbamazepine significantly increased the clearance of quetiapine.
Croatian: U ispitivanju na bolesnicima s ciljem procjene farmakokinetike kvetiapina, primjenjenog u višekratnim dozama prije i za trajanja liječenja karbamazepinom (poznatim induktorom jetrenih enzima), istodobna primjena karbamazepina značajno je povećala klirens kvetiapina.
English: Gender: The pharmacokinetics of quetiapine does not differ between men and women.
Croatian: Farmakokinetika kvetiapina se ne razlikuje kod muškaraca i žena.
English: As with other antipsychotics, caution should be exercised when quetiapine is prescribed in patients with cardiovascular disease or family history of QT prolongation.
Croatian: Kao i prilikom primjene drugih antipsihotika, nužan je oprez pri propisivanju kvetiapina u bolesnika s kardiovaskularnim bolestima ili bolesnicima u čijoj obiteljskoj anamnezi postoji podatak o produljenju QT intervala.
English: For patients who were randomized to quetiapine, the mean weight gain during the open label period was 2.56 kg, and by week 48 of the randomized period, the mean weight gain was 3.22 kg, compared to open label baseline.
Croatian: Za bolesnike koji su randomizirani u skupinu s kvetiapinom srednji dobitak na težini tijekom razdoblja ispitivanja otvorenog tipa bio je 2,56 kg, a do 48. tjedna randomizacijskog razdoblja srednji dobitak na težini bio je 3,22 kg u usporedbi s početnim vrijednostima otvorenog razdoblja ispitivanja.
English: Seroquel XR contains lactose which is a type of sugar.
Croatian: Seroquel XR sadrži laktozu, što je jedna vrsta šećera.
English: A meta analysis of placebo controlled clinical trials of antidepressant drugs in adult patients with psychiatric disorders showed an increased risk of suicidal behaviour with antidepressants compared to placebo in patients less than 25 years old.
Croatian: Meta-analiza placebom kontroliranih kliničkih ispitivanja antidepresiva u odraslih bolesnika s psihijatrijskim poremećajima je pokazala povećani rizik od suicidalnog ponašanja pri uzimanju antidepresiva u usporedbi s placebom u bolesnika mlađih od 25 godina.
English: Higher rates of extrapyramidal symptoms were seen in quetiapine treated patients compared to those treated with placebo in short-term, placebo-controlled clinical trials in MDD and bipolar depression.
Croatian: Veće stope ekstrapiramidnih simptoma uočene su u bolesnika liječenih kvetiapinom u usporedbi s onima liječenima placebom u kratkoročnim, placebom kontroliranim kliničkim ispitivanjima u velikom depresivnom poremećaju i bipolarnoj depresiji.
English: • Do not use Seroquel XR after the expiry date which is stated on the container after EXP.
Croatian: • Seroquel XR se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju iza “Rok valjanosti“ ili “EXP“.
English: Long-term efficacy and safety in patients with MDD has not been evaluated as add-on therapy, however long-term efficacy and safety has been evaluated in adult patients as monotherapy (see Section 5.1).
Croatian: Dugoročna djelotvornost i sigurnost primjene, kao dodatne terapije, u bolesnika s velikim depresivnim poremećajem nije procijenjena, ali je procijenjena dugoročna djelotvornost i sigurnost primjene kao monoterapije u odraslih bolesnika (vidjeti dio 5.1).
English: Given the observed risk for worsening of their metabolic profile, including changes in weight, blood glucose (see hyperglycemia) and lipids, which was seen in clinical studies, patients' metabolic parameters should be assessed at the time of treatment initiation and changes in these parameters should be regularly controlled for during the course of treatment.
Croatian: S obzirom na rizik od pogoršanja metaboličkog profila primijećenog u kliničkim ispitivanjima, koje uključuje promjene tjelesne težine, glukoze u krvi (vidjeti odlomak o hiperglikemiji) i lipida, potrebno je ocijeniti metaboličke parametre bolesnika pri uvođenju liječenja, a promjene tih parametara treba redovito kontrolirati tijekom liječenja.
English: Elevations in blood creatine phosphokinase
Croatian: Pretrage povećanja razine kreatin fosfokinaze u krvi
English: • You have problems with your liver.
Croatian: • ako imate jetrenih tegoba.
English: When Seroquel XR administered once daily is compared to the same total daily dose of immediate-release quetiapine fumarate (Seroquel immediate release) administered twice daily, the area under the plasma concentration-time curve (AUC) is equivalent, but the maximum plasma concentration (Cmax) is 13% lower at steady state.
Croatian: primijenjenog u jednokratnoj dnevnoj dozi, s profilom kvetiapinfumarata u obliku tableta s trenutnim otpuštanjem (Seroquel tablete), primijenjenim dva puta dnevno u istovjetnoj ukupnoj dnevnoj dozi, površina ispod krivulje plazmatska koncentracija-vrijeme (AUC) je ekvivalentna, no maksimalna koncentracija lijeka u plazmi (Cmax), 13 je posto niža u stanju dinamičke ravnoteže.
English: • Symptoms of withdrawal may occur in newborn babies of mothers that have used Seroquel XR
Croatian: • simptomi ustezanja (prekida primjene lijeka) mogu nastupiti u novorođenčadi čije su majke uzimale Seroquel XR tijekom trudnoće
English: • Do not use Seroquel after the expiry date which is stated on the container after EXP.
Croatian: • Seroquel se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju iza "Rok valjanosti" ili "EXP".
English: With respect to weight gain, when adjusting for normal growth over the longer term, an increase of at least 0.5 standard deviation from baseline in Body Mass Index (BMI) was used as a measure of a clinically significant change; 18.3% of patients who were treated with quetiapine for at least 26 weeks met this criterion.
Croatian: Što se tiče porasta tjelesne težine, kada se dugoročno korigira za normalan rast, kao mjera klinički značajne promjene koristilo se povećanje od najmanje 0,5 standardne devijacije od početne vrijednosti indeksa tjelesne mase (BMI); taj je kriterij zadovoljilo 18,3% bolesnika liječenih kvetiapinom najmanje 26 tjedana.
English: Cytochrome P450 (CYP) 3A4 is the enzyme that is primarily responsible for the cytochrome P450 mediated metabolism of quetiapine.
Croatian: Citokrom P450 (CYP) 3A4 je enzim koji je prvenstveno odgovoran za metaboliziranje kvetiapina posredovano citokromom P450.
English: In post-marketing, QT prolongation was reported with quetiapine at the therapeutic doses (see Section 4.8) and in overdose (see Section 4.9).
Croatian: U razdoblju nakon stavljanja lijeka u promet zabilježeno je produljenje QT intervala tijekom primjene kvetiapina u terapijskim dozama (vidjeti dio 4.8) i prilikom predoziranja (vidjeti dio 4.9).
English: Neuroleptic malignant syndrome has been associated with antipsychotic treatment, including quetiapine (see section 4.8).
Croatian: Neuroleptički maligni sindrom povezan je s uzimanjem antipsihotika, uključujući kvetiapin (vidjeti dio 4.8).
English: Talk to your doctor or pharmacist before taking Seroquel if:
Croatian: Obratite se svom liječniku ili ljekarniku prije nego uzmete Seroquel:
English: 4-Day Starterpack
Croatian: 4-dnevno početno pakiranje
English: • A combination of high temperature (fever), sweating, stiff muscles, feeling very drowsy or faint (a disorder called “neuroleptic malignant syndrome).”
Croatian: • kombinacija visoke tjelesne temperature (vrućica), znojenja, ukočenosti mišića, osjećaja izrazite omamljenosti ili nesvjestice (poremećaj koji se zove "neuroleptički maligni sindrom")
English: 8 tablets
Croatian: 8 tableta
English: Inappropriate antidiuretic hormone secretion
Croatian: neodgovaraju će izlučivanje antidiuretskog hormona
English: Shift from >132 mmol/L to ≤132 mmol/L on at least one occasion.
Croatian: Barem jednom izmjeren pomak sa >132 mmol/L na ≤ 132 mmol/L.
English: Lactose:
Croatian: Laktoza:
English: Increases in the hormone prolactin could in rare cases lead to the following: o Boys and girls to have swelling of breasts and unexpectedly produce breast milk o Girls to have no monthly period or irregular periods
Croatian: U rijetkim slučajevima povećanje razine hormona prolaktina može dovesti do slijedećeg: o oticanje dojki i neočekivano izlučivanje mlijeka iz dojki kod dječaka i djevojčica o izostanka mjesečnice ili neredovite mjesečnice kod djevojčica
English: As quetiapine is extensively metabolised by the liver, elevated plasma levels are expected in the population with hepatic impairment.
Croatian: Kako se kvetiapin opsežno metabolizira u jetri, u populaciji s oštećenjem funkcije jetre očekuje se povećanje kvetiapina u plazmi.
English: • Swelling of arms or legs.
Croatian: • oticanje ruku ili nogu
English: In elderly patients with major depressive episodes in MDD, dosing should begin with 50 mg/day on Days 1-3, increasing to 100 mg/day on Day 4 and 150 mg/day on Day 8.
Croatian: Kod starijih bolesnika sa velikim depresivnim epizodama u velikom depresivnom poremećaju, doziranje je potrebno započeti sa 50 mg/dan prvi, drugi i treći dan, povećavajući dozu na 100 mg/dan četvrti dan te na 150 mg/dan osmi dan.
English: Based on clinical trial adverse event reports of blood creatine phosphokinase increase not associated with neuroleptic malignant syndrome 15.
Croatian: Temeljeno na prijavama štetnog događaja porasta kreatin fosfokinaze u krvi u kliničkim ispitivanjima, a koji nisu povezani s neuroleptičkim malignim sindromom.