FrancophonIA/ELRC3.0 huggingface dataset:
English: AUC12: ↓ 45 % (↓ 38 to ↓ 51) Cmax: ↓ 51 % (↓ 37 to ↓ 62) Efavirenz concentrations not measured, no effect is expected.
Danish: AUC12:  45 % ( 38 til  51) Cmax:  51 % ( 37 til  62) Koncentrationen af efavirenz er ikke målt, ingen effekt forventes.
English: Warfarin or acenocoumarol (medicines used to reduce clotting of the blood): your doctor may need to adjust your dose of warfarin or acenocoumarol.
Danish: • Warfarin eller acenocoumarol (medicin til at forebygge blodpropper): lægen vil måske være nødt til at justere din warfarin- eller acenocoumaroldosis.
English: The nervous system symptoms tend to occur when treatment is first started, but generally decrease in the first few weeks.
Danish: Symptomerne fra nervesystemet har tilbøjelighed til at optræde, lige når behandlingen startes, men aftager i reglen i løbet af de første få uger.
English: Stocrin can reduce the amount of statins in your blood.
Danish: Stocrin kan nedsætte mængden af statiner i blodet.
English: STOCRIN 600 mg film-coated tablets Dark yellow, capsule-shaped, debossed with “225” on one side.
Danish: STOCRIN 600 mg filmovertrukne tabletter Mørkegule, kapselformede, præget med “225” på den ene side.
English: uncommon affect lability, aggression, confusional state, euphoric mood, hallucination, mania, paranoia, psychosis
Danish: Affektlabilitet, aggression, konfusion, eufori, hallucinationer, mani, paranoia, psykose suicidalforsøg, suicidaltanker, katatoni*
English: Each ml contains: efavirenz 30 mg
Danish: Hver ml indeholder: Efavirenz 30 mg
English: Outer carton: STOCRIN 600 mg
Danish: Ydre pakning: STOCRIN 600 mg
English: (400/100 mg twice daily/600 mg once daily)
Danish: (400/100 mg to gange dagligt/600 mg én gang dagligt)
English: - if you have a history of convulsions (fits or seizures) or if you are being treated with anticonvulsant therapy such as carbamazepine, phenobarbital and phenytoin.
Danish: - hvis du tidligere har haft krampeanfald, eller hvis du får medicin mod krampeanfald, for eksempel carbamazepin, phenobarbital og phenytoin.
English: Stocrin contains efavirenz and may cause dizziness,impaired concentration, and drowsiness.
Danish: Stocrin indeholder efavirenz og kan give svimmelhed, nedsat koncentrationsevne og døsighed.
English: Excipient with known effect Each film-coated tablet contains 249.6 mg of lactose (as monohydrate).
Danish: Hjælpestof, som behandleren skal være opmærksom på Hver filmovertrukken tablet indeholder 249,6 mg lactose (som monohydrat).
English: STOCRIN 600 mg film-coated tablets STOCRIN 50 mg film-coated tablets STOCRIN 200 mg film-coated tablets
Danish: STOCRIN 600 mg filmovertrukne tabletter STOCRIN 50 mg filmovertrukne tabletter STOCRIN 200 mg filmovertrukne tabletter
English: Psychiatric adverse reactions have been reported in patients treated with efavirenz.
Danish: Der er indberettet psykiske bivirkninger hos patienter, der er behandlet med efavirenz.
English: AUC: ↓ 31 % (↓ 8 to ↓ 47) Cmin: ↓ 40 %
Danish: AUC: ↓ 31 % (↓ 8 til ↓ 47) Cmin: ↓ 40 %
English: Stocrin can reduce or increase the amount of anticonvulsant in your blood.
Danish: Stocrin kan nedsætte eller øge mængden af krampestillende medicin i blodet.
English: • Before giving the dose of the oral solution make sure that the patient is sitting or standing upright.
Danish: • Patienten skal stå oprejst eller sidde ret op, når den orale væske skal gives.
English: Warfarinor acenocoumarol(medicines used to reduce clotting of the blood): your doctor may need to adjust your dose of warfarin or acenocoumarol.
Danish: • Warfarin og acenocoumarol (medicin til at forebygge blodpropper): lægen vil måske være nødt til at justere din warfarin- eller acenocoumaroldosis.
English: - any signs of skin rash.
Danish: - alle tegn på hududslæt.
English: Non-sustained convulsions were observed in some monkeys receiving efavirenz for ≥ 1 year, at doses yielding plasma AUC values 4- to 13-fold greater than those in humans given the recommended dose (see sections 4.4 and 4.8).
Danish: Der er set ikkevedvarende krampeanfald hos nogle aber, der fik efavirenz i  1 år, ved doser der gav plasma AUCværdier 4-13 gange højere end dem, der er set hos mennesker ved anbefalet dosis (se pkt.
English: Hormonal contraceptive, such as birth control pills, an injected contraceptive (for example, Depo-Provera), or a contraceptive implant (for example, Implanon): you must also use a reliable barrier method of contraception (see Pregnancy, breast-feeding and fertility).
Danish: • Hormonel prævention, såsom p-piller, prævention som indsprøjtning (fx Depo-Provera) eller et kontraceptivt implantat (fx Nexplanon): Du skal også bruge pålidelig barriereprævention (se Graviditet og amning), da Stocrin kan bevirke, at virkningen af hormonel prævention nedsættes.
English: Dose (ml) Children 3 - < 5 years
Danish: Børn 3 - < 5 år
English: Cmax: ↑ 11 % (↑ 6 to ↑ 16) Cmin: ↔ (CYP3A4 induction)
Danish: Cmax: ↑ 11% (↑ 6 til ↑ 16) Cmin: ↔ (CYP3A4-induktion)
English: An oral syringe with a push-in bottle-neck adapter is included in the carton.
Danish: En oral sprøjte med adapter til at sætte i flaskens hals følger med kartonen.
English: Injection: Depo-medroxyprogesterone acetate (DMPA)/Efavirenz (150 mg IM single dose DMPA)
Danish: Depomedroxyprogesteronacetat (DMPA)/efavirenz (150 mg enkeltdosis DMPA intramuskulært)
English: EU/1/99/111/005 - bottle
Danish: EU/1/99/111/005 - flaske
English: Ethinyloestradiol+Norgestimate/ Efavirenz (0.035 mg+0.25 mg once daily/600 mg once daily)
Danish: Ethinylestradiol + norgestimat/efavirenz (0,035 mg + 0,25 mg én gang dagligt/600 mg én gang dagligt)
English: When taken with rifampicin in patients weighing 50 kg or greater, increasing efavirenz daily dose to 800 mg may provide exposure similar to a daily dose of 600 mg, when taken without rifampicin.
Danish: Taget sammen med rifampicin kan øgning af efavirenzdosis til 800 mg dagligt hos voksne, der vejer 50 kg eller derover, give samme eksponering som en daglig dosis på 600 mg taget uden rifampicin.
English: Ritonavir: Morning AUC: ↑ 18 % (↑ 6 to
Danish: Ritonavir: AUC morgen: ↑ 18% (↑ 6 til ↑
English: < 400 copies/ml (95 % C.I.
Danish: < 400 kopier/ml (95% C.I.)
English: AUC: ↓ 7 % (↓ 23 to ↑ 13) * Cmax: ↑ 23 % (↓ 1 to ↑ 53) * Efavirenz:
Danish: AUC: ↓ 7 % (↓ 23 til ↑ 13)* Cmax: ↑ 23 % (↓ 1 til ↑ 53)* Efavirenz:
English: Medicines used to treat heart rhythm problems such as flecainide or metoprolol.
Danish: • Lægemidler med indvirkning på hjerterytmen: - Lægemidler til behandling af problemer med hjerterytmen: fx flecainid eller metoprolol.
English: If efavirenz is coadministered with voriconazole, the voriconazole maintenance dose must be increased to 400 mg every 12 hours and the efavirenz dose must be reduced by 50 %, i.e., to 300 mg once daily.
Danish: Hvis efavirenz administreres sammen med voriconazol, skal vedligeholdelsesdosis af voriconazol øges til 400 mg hver 12. time, og dosis af efavirenz skal reduceres med 50%, dvs. til 300 mg en gang dagligt.
English: If a patient is already taking St. John's wort, stop St. John's wort, check viral levels and if possible efavirenz levels.
Danish: Hvis patienten allerede tager perikon, skal dette seponeres, og de virale niveauer og evt. efavirenzkoncentrationen skal kontrolleres.
English: Excipient with known effect Each film-coated tablet contains 20.8 mg of lactose (as monohydrate).
Danish: Hjælpestof, som behandleren skal være opmærksom på Hver filmovertrukken tablet indeholder 20,8 mg lactose (som monohydrat).
English: AUC: ↓ 17% Cmax: ↔ (CYP3A4 induction)
Danish: AUC: ↓ 17 % Cmax: ↔ (CYP3A4-induktion)
English: Co-administration with elbasvir/grazoprevir due to the expected significant decreases in elbasvir and grazoprevir plasma concentrations (see section 4.5).
Danish: Samtidig administration med elbasvir/grazoprevir på grund af de forventede signifikante fald i plasmakoncentrationen af elbasvir og grazoprevir (se pkt.
English: < 50 copies/ml (95 % C.I.
Danish: <50 kopier/ml (95% C.I.)
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Danish: Hos nogle patienter med fremskreden hiv-infektion (aids), som tidligere har haft en infektion, som kun fremkommer under særlige betingelser (opportunistisk infektion), kan tegn og symptomer på betændelse fra tidligere infektioner forekomme kort efter, at anti-hiv-behandlingen er startet.
English: Uncommon (affects 1 to 10 users in 1,000) - nervousness, forgetfulness, confusion, fitting (seizures), abnormal thoughts - blurred vision - a feeling of spinning or tilting (vertigo) - pain in the abdomen (stomach) caused by inflammation of the pancreas - allergic reaction (hypersensitivity) that may cause severe skin reactions (erythema multiforme,
Danish: Ikke almindelige (berører 1 til 10 ud af 1.000 brugere) - Nervøsitet, glemsomhed, forvirring, anfald (kramper), unormale tanker - Sløret syn - Snurrende eller gyngende fornemmelse (svimmelhed) - Smerter i maven forårsaget af betændelse i bugspytkirtlen - Allergisk reaktion (overfølsomhed) som kan medføre alvorlige hudreaktioner (erythema multiforme, Stevens-Johnsons syndrom) - Gulfarvning af hud eller øjne, kløe, eller smerter i maven forårsaget af betændelse i leveren - Brystforstørrelse hos mænd - Aggressiv opførsel, humørsvingninger, at se eller høre ting, som i virkeligheden ikke er der
English: Stocrin is recommended to be taken on an empty stomach preferably at bedtime.
Danish: Det anbefales at tage Stocrin på tom mave, helst ved sengetid.
English: How to take Stocrin
Danish: Sådan skal du tage Stocrin
English: Medium chain triglycerides Benzoic acid (E210) Strawberry/mint flavour
Danish: Triglycerider, middelkædelængde Benzoesyre (E210) Jordbær/mintsmag
English: The most notable adverse reactions associated with efavirenz are rash and nervous system symptoms (see section 4.4).
Danish: De væsentligste bivirkninger i forbindelse med efavirenz er udslæt og symptomer fra nervesystemet (se pkt.
English: When efavirenz is co-administered with voriconazole, the voriconazole maintenance dose must be increased to 400 mg twice daily and the efavirenz dose must be reduced by 50 %, i.e., to 300 mg once daily.
Danish: Når efavirenz administreres sammen med voriconazol, bør vedligeholdelsesdosis for voriconazol øges til 400 mg to gange dagligt, og efavirenz-dosis skal reduceres med 50%, dvs. 300 mg én gang dagligt.
English: Co-administration of efavirenz with a fixed combination tablet containing efavirenz, emtricitabine, and tenofovir disoproxil, is not recommended unless needed for dose adjustment (for example, with rifampicin).
Danish: Efavirenz og en fastdosis-kombinationstablet indeholdende efavirenz, emtricitabin og tenofovirdisoproxil bør ikke administreres samtidigt, medmindre det er nødvendigt for dosisjustering (fx ved samtidig behandling med rifampicin).
English: STOCRIN 30 mg/ml oral solution
Danish: STOCRIN 30 mg/ml oral opløsning
English: Common (affects 1 to 10 users in 100) - abnormal dreams, difficulty concentrating, dizziness, headache, difficulty sleeping, drowsiness,
Danish: Almindelige (berører 1 til 10 ud af 100 brugere) - Unormale drømme, koncentrationsbesvær, svimmelhed, hovedpine, søvnbesvær, døsighed - Koordinerings- eller balanceproblemer - Mavesmerter, diarré, kvalme, opkastning - Kløe - Træthed - Bekymring, depression
English: Other medicines used for HIV infection: protease inhibitors: darunavir, indinavir, lopinavir/ritonavir, ritonavir, ritonavir boosted atazanavir, saquinavir or fosamprenavir/saquinavir.
Danish: • Anden medicin mod hiv-infektion: proteasehæmmere: darunavir, indinavir, lopinavir/ritonavir, ritonavir, atazanavir forstærket af ritonavir, saquinavir eller fosamprenavir/saquinavir.
English: AUC: ↓ 60 % (↓ 52 to ↓ 68) Cmax: ↓ 62 % (↓ 55 to ↓ 78) (CYP3A4 induction) Co-administration of efavirenz with atorvastatin, pravastatin, or simvastatin did not affect efavirenz AUC or Cmax values.
Danish: AUC: ↓ 60% (↓ 52 til ↓ 68) Cmax: ↓ 62% (↓ 55 til ↓ 78) (CYP3A4-induktion) Samtidig administration af efavirenz og atorvastatin, pravastatin eller simvastatin påvirkede ikke efivarenz' AUCeller Cmax-værdier.
English: Outer carton: STOCRIN 50 mg tablets
Danish: Ydre pakning: STOCRIN 50 mg tabletter
English: AUC: ↔*/** (↓ 10 to ↑ 26) Cmax: ↔*/** (↓ 5 to ↑ 26) Cmin: ↑ 12 %*/** (↓ 16 to ↑ 49) (CYP3A4 induction).
Danish: AUC: */** ( 10 til  26) Cmax: */** ( 5 til  26) Cmin:  12*/** ( 16 til  49) (CYP3A4-induktion).
English: EFV, efavirenz; ZDV, zidovudine; 3TC, lamivudine; IDV, indinavir.
Danish: Standard afvigelse på middelværdi EFV, efavirenz; ZDV, zidovudin, 3TC, lamivudin; IDV, indinavir.
English: AUC: ↓ 36 % C12: ↓ 21 % Cmax: ↓ 36 % (UGT1A1 induction)
Danish: AUC:  36% C12:  21% Cmax:  36% (UGT1A1-induktion)
English: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil with sofosbuvir/velpatasvir has been shown to significantly decrease plasma concentrations of velpatasvir due to CYP3A induction by efavirenz, which may result in loss of therapeutic effect of velpatasvir.
Danish: Det er påvist, at administration af efavirenz/emtricitabin/ tenofovirdisoproxil sammen med sofosbuvir/velpatasvir sænker plasmakoncentrationen af velpatasvir signifikant som følge af CYP3A-induktion forårsaget af efavirenz, hvilket kan resultere i tab af terapeutisk effekt af velpatasvir.
English: Excipient with known effect Each film-coated tablet contains 83.2 mg of lactose (as monohydrate).
Danish: Hjælpestof, som behandleren skal være opmærksom på Hver filmovertrukken tablet indeholder 83,2 mg lactose (som monohydrat).
English: Stocrin 30 mg/ml oral solution efavirenz
Danish: Stocrin 30 mg/ml oral opløsning efavirenz
English: Co-administration of glecaprevir/pibrentasvir with efavirenz is not recommended.
Danish: Samtidig administration af glecaprevir/pibrentasvir med efavirenz anbefales ikke.
English: There is a potential for reduction or increase in the plasma concentrations of phenytoin, phenobarbital and other anticonvulsants that are substrates of CYP450 isoenzymes when co-administered with efavirenz.
Danish: Plasmakoncentrationen for phenytoin, phenobarbital og andre antikonvulsiva, som er substrater for CYP-isoenzymer, kan eventuelt falde eller stige, når disse administreres samtidigt med efavirenz.
English: Co-administration of glecaprevir/pibrentasvir with efavirenz is not recommended (see section 4.5).
Danish: Samtidig administration af glecaprevir/pibrentasvir med efavirenz anbefales ikke (se pkt.
English: Stocrin oral solution (30 mg/ml)
Danish: Stocrin oral opløsning (30 mg/ml)
English: Dose adjustments of atorvastatin may be required (refer to the Summary of Product Characteristics for the atorvastatin).
Danish: Dosisjustering af atorvastatin kan være påkrævet (se SPC for atorvastatin).
English: ‡, disturbance in attention (3.6 %), dizziness (8.5 %), headache (5.7 %), somnolence uncommon agitation, amnesia, ataxia, coordination abnormal, convulsions, thinking abnormal, tremor
Danish: ‡, opmærksomhedsforstyrrelse (3,6%), svimmelhed (8,5%), hovedpine (5,7%), døsighed (2,0%)
English: Ginkgo biloba extracts (herbal preparation)
Danish: • Ginkgo biloba (et naturlægemiddel)
English: Outer carton: STOCRIN 200 mg tablets
Danish: Ydre pakning: STOCRIN 200 mg tabletter
English: AUC: ↓ 40 % (↓ 26 to ↓ 57) Cmax: ↓ 18 % (↓ 59 to ↑ 12)
Danish: AUC: ↓ 40% (↓ 26 til ↓ 57) Cmax: ↓ 18% (↓ 59 til ↑ 12)
English: Rapid squirting into the mouth may cause choking.
Danish: Hvis medicinen sprøjtes hurtigt ind i munden, kan patienten få væsken galt i halsen.
English: Cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to combination antiretroviral therapy (CART).
Danish: Der er rapporteret om tilfælde af osteonekrose hos patienter, der har fremskreden hiv-sygdom og/eller hos patienter der befinder sig i langvarig kombinationsbehandling med antiretrovirale lægemidler (CART).
English: Your doctor may consider giving you an alternative medicine or changing the dose of the proteaseinhibitors.
Danish: Lægen kan overveje at give dig anden medicin eller at ændre dosen af proteasehæmmere.
English: AUC: ↓ 4 % (↓ 0 to ↓ 31) Cmax: ↓ 47 % (↓ 9 to ↓ 51) Total active HMG Co-A reductase inhibitors:
Danish: AUC: ↓ 4% (↓ 0 til ↓ 31) Cmax: ↓ 47% (↓ 9 til ↓ 51) Totalt aktive HMG Co-A reduktasehæmmere:
English: Your doctor will check your cholesterol levels and will consider changing the dose of your statin, if needed.
Danish: Lægen vil kontrollere dit kolesterol i blodet og måske ændre statindosis.
English: AUC : ↓ 13 % Cmin : ↓ 31 % Cmax: ↓ 15% (CYP3A4 induction) Efavirenz:
Danish: AUC:  13 % Cmin:  31 % Cmax:  15 % (CYP3A4-induktion) Efavirenz:
English: Cmin: ↓ 12 % (↓ 24 to ↑ 1) (CYP3A4 induction)
Danish: Cmin: ↓ 12% (↓ 24 til ↑ 1) (CYP3A4-induktion)
English: Tablet core: Croscarmellose sodium, Microcrystalline cellulose, Sodium laurilsulfate, Hydroxypropylcellulose, Lactose monohydrate, Magnesium stearate
Danish: Tabletkerne: Croscarmellosenatrium, mikrokrystallinsk cellulose, natriumlaurilsulfat, hydroxypropylcellulose, lactosemonohydrat, magnesiumstearat
English: AUC: ↓ 34 % (↓ 21 to ↓ 41) Cmax: ↓ 20 % (↓ 2 to ↓ 26)
Danish: AUC: ↓ 34% (↓ 21 til ↓ 41) Cmax: ↓ 20% (↓ 2 til ↓ 26)
English: - bepridil (used to treat heart disease) - cisapride (used to treat heartburn) - ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine) (used to treat migraine and cluster headaches) - midazolam or triazolam (used to help you sleep) - pimozide, imipramine, amitriptyline or clomipramine (used to treat certain mental conditions) - St. John's wort (Hypericum perforatum) (a herbal remedy used for depression and anxiety) - flecainide, metoprolol (used to treat irregular heart beat) - certain antibiotics (macrolides, fluoroquinolones, imidazole) - triazole antifungal agents - certain antimalarial treatments - methadone (used to treat opiate addiction) - elbasvir/grazoprevir
Danish: - astemizol eller terfenadin (mod symptomer på allergi) - bepridil (mod hjertesygdom) - cisaprid (mod halsbrand) - sekalealkaloider (fx ergotamin, dihydroergotamin, ergonovin og methylergonovin) (mod migræne og klyngehovedpine) - midazolam eller triazolam (mod søvnløshed) - pimozid, imipramin, amitriptylin eller clomipramin (mod visse sindstilstande) - perikon (Hypericum perforatum) (et naturlægemiddel mod depression og angst) - flecainid, metoprolol (til behandling af uregelmæssig hjerterytme) - visse antibiotika (makrolider, fluoroquinoloner, imidazol) - triazol svampemidler - visse malariamidler - methadon (til behandling af opioidmisbrug) - elbasvir/grazoprevir.
English: AUC: ↓ 69 % (↓ 62 to ↓ 73) Cmax: ↓ 76 % (↓ 63 to ↓ 79) Simvastatin acid:
Danish: AUC: ↓ 69% (↓ 62 til ↓ 73) Cmax: ↓ 76% (↓ 63 til ↓ 79) Simvastatinsyre:
English: AUC: ↓ 58 % (↓ 39 to ↓ 68) Cmax: ↓ 51 % (↓ 32 to ↓ 58) Total active HMG Co-A reductase inhibitors:
Danish: AUC: ↓ 58% (↓ 39 til ↓ 68) Cmax: ↓ 51% (↓ 32 til ↓ 58) Totalt aktive HMG Co-A reduktasehæmmere:
English: Carcinogenicity studies in male mice, male and female rats were negative.
Danish: Karcinogenicitetsundersøgelser på hanmus samt han- og hunrotter var negative.
English: AUC: ↓ 35 % (↓ 13 to ↓ 40) Cmax: ↓ 13 % (↓ 0 to ↓ 23) 4-hydroxy atorvastatin:
Danish: AUC: ↓ 35% (↓ 13 til ↓ 40) Cmax: ↓ 13% (↓ 0 til ↓ 23) 4-hydroxy atorvastatin:
English: The length of combination antiretroviral therapy, corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index, among others, may be some of the many risk factors for developing this disease.
Danish: Til de mange risikofaktorer for udvikling af denne sygdom hører blandt andre: Længden af den antiretrovirale kombinationsbehandling, anvendelse af kortikosteroider, alkoholforbrug, alvorligt nedsat immunforsvar samt højere Body Mass Index (BMI).
English: Other macrolide antibiotics (e.g., erythromycin)/Efavirenz
Danish: Andre makrolidantibiotika (fx erythromycin)/efavirenz
English: Efavirenz must not be administered concurrently with terfenadine, astemizole, cisapride, midazolam, triazolam, pimozide, bepridil, or ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine) since inhibition of their metabolism may lead to serious, life-threatening events (see section 4.3).
Danish: Efavirenz må ikke administreres sammen med terfenadin, astemizol, cisaprid, midazolam, triazolam, pimozid, bepridil eller sekalealkaloider (fx ergotamin, dihydroergotamin, ergonovin og methylergonovin), da hæmning af disses metabolisme kan føre til alvorlige livstruende hændelser (se pkt.
English: A reliable method of barrier contraception must be used in addition to hormonal contraceptives (see section 4.6).
Danish: En pålidelig kontraceptiv barrieremetode skal anvendes som supplement til hormonelle kontraceptiva (se pkt.
English: Co-administration of simeprevir with efavirenz is not recommended.)
Danish: Samtidig administration af simeprevir og efavirenz frarådes.
English: In 35 patients receiving efavirenz 600 mg once daily, steady state Cmax was 12.9 ± 3.7 M (29 %) [mean ± S.D. (% C.V.)], steady state Cmin was 5.6 ± 3.2 M (57 %), and AUC was 184 ± 73 M·h (40 %).
Danish: Hos 35 patienter, der fik efavirenz 600 mg 1 gang dagligt, var det gennemsnitlige steady-state Cmax 12,9 ± 3,7 M (29%) [gennemsnit ± S.D. (% C.V.
English: Evening AUC: ↔ Morning Cmax: ↑ 24 % (↑ 12 to
Danish: AUC aften: ↔ Cmax morgen: ↑ 24% (↑ 12 til ↑
English: Bupropion (a medicine used to treat depression or to helpyou stop smoking): your doctor may need to change your dose of bupropion.
Danish: • Bupropion (medicin mod depression eller til rygeafvænning): lægen vil måske være nødt til at ændre din bupropiondosis.
English: Dose adjustments of simvastatin may be required (refer to the Summary of Product Characteristics for simvastatin).
Danish: Dosisjustering af simvastatin kan være påkrævet (se SPC for simvastatin).
English: Norepinephrine and dopamine reuptake inhibitor Bupropion/Efavirenz [150 mg single dose (sustained release)/600 mg once daily]
Danish: Noradrenalin og dopamin genoptagelseshæmmer Bupropion/efavirenz [150 mg enkeltdosis (som depot)/600 mg én gang dagligt]
English: AUC: ↓ 43 % (↓ 34 to ↓ 50) Cmax: ↓ 12 % (↓ 1 to ↓ 26) 2-hydroxy atorvastatin:
Danish: AUC: ↓ 43% (↓ 34 til ↓ 50) Cmax: ↓ 12% (↓ 1 til ↓ 26) 2-hydroxy atorvastatin:
English: Ear and labyrinth disorders uncommon tinnitus
Danish: Øre og labyrint Ikke almindelig
English: Integrase strand transfer inhibitor Raltegravir/Efavirenz (400 mg single dose/ - )
Danish: Intergrase hæmmer af genoverførelse Raltegravir/efavirenz (400 mg enkeltdoser/ - )
English: AUC: ↓ 75 % (↓ 59 to ↓ 84) Cmax: ↓ 64 % (↓ 57 to ↓ 69) Cmin: ↓ 62 % (↓ 44 to ↓ 75) N-monodesmethyl diltiazem: AUC: ↓ 37 % (↓ 17 to ↓ 52) Cmax: ↓ 28 % (↓ 7 to ↓ 44) Cmin: ↓ 37 % (↓ 17 to ↓ 52) Efavirenz:
Danish: AUC: ↓ 75% (↓ 59 til ↓ 84) Cmax: ↓ 64% (↓ 57 til ↓ 69) Cmin: ↓ 62% (↓ 44 til ↓ 75) N-monodesmethyl diltiazem: AUC: ↓ 37% (↓ 17 til ↓ 52) Cmax: ↓ 28% (↓ 7 til ↓ 44) Cmin: ↓ 37% (↓ 17 til ↓ 52) Efavirenz:
English: Stocrin 50 mg film-coated tablets are supplied in bottles of 30 tablets.
Danish: Stocrin 50 mg filmovertrukne tabletter fås i beholdere med 30 tabletter.
English: AUC: ↔* (↓ 9 to ↑ 10) Cmax: ↑ 17 %* (↑ 8 to ↑ 27) Cmin: ↓ 42 %* (↓ 31 to ↓ 51)
Danish: AUC: * ( 9 til  10) Cmax:  17 %* ( 8 til  27) Cmin:  42 %* ( 31 til  51)
English: • Each ml of Stocrin oral solution contains 30 mg of the active substance efavirenz.
Danish: • Hver milliliter Stocrin oral opløsning indeholder 30 mg af det aktive stof efavirenz.
English: Stocrin 600 mg film-coated tablets are supplied in bottles of 30 tablets.
Danish: Stocrin 600 mg filmovertrukne tabletter fås i beholdere med 30 tabletter.
English: AUC: ↓ 83 % (↓ 79 to ↓ 87) Cmax: ↓ 80 % (↓ 77 to ↓ 83) Cmin: ↓ 86 % (↓ 80 to ↓ 90) (induction of metabolism) Efavirenz: no clinically significant interaction.
Danish: AUC: ↓ 83% (↓ 79 til ↓ 87) Cmax: ↓ 80% (↓ 77 til ↓ 83) Cmin: ↓ 86% (↓ 80 til ↓ 90) (induktion af metabolisme).
English: • Turn the bottle upside down with the syringe still in place.
Danish: • Vend flasken på hovedet, stadig med sprøjten placeret i flaskeadapteren.