FrancophonIA/ELRC3.0 huggingface dataset:
English: Starting dose of 50 IU/kg, 3 times per week, followed if necessary by a dosage increase with 25 IU/kg increments (3 times per week) until the desired goal is achieved (this should be done in steps of at least four weeks).
Danish: Startdosis på 50 IE/kg 3 gange ugentlig, om nødvendigt efterfulgt af dosisøgning med forhøjelser à 25 IE/kg (3 gange ugentlig), indtil ønsket værdi er opnået (dette bør ske med intervaller på mindst 4 uger).
English: • Retacrit is used in moderately anaemic adults about to have major orthopaedic surgery (for example hip or knee replacement operations), to reduce the potential need for blood transfusions.
Danish: • Retacrit bruges til voksne med moderat blodmangel, som skal gennemgå en større ortopædisk operation (f.eks. udskiftning af hofte eller knæ) til at nedsætte risikoen for, at det kan være nødvendigt med blodtransfusion.
English: In cases where there is a medical need to shorten the lead time before surgery to less than three weeks, Retacrit 300 IU/kg should be administered subcutaneously daily for 10 consecutive days prior to surgery, on the day of surgery and for four days immediately thereafter.
Danish: I tilfælde, hvor der er klinisk behov for at afkorte tiden før operationen til mindre end tre uger, skal der gives en dosis på 300 IE/kg Retacrit administreret subkutant dagligt i 10 konsekutive dage før operationen, på operationsdagen samt i 4 dage umiddelbart efter.
English: In these trials, epoetin alfa administered 3 times per week and once weekly has been shown to increase haemoglobin and decrease transfusion requirements after the first month of therapy in anaemic cancer patients.
Danish: Disse studier viste, at epoetin alfa administreret 3 gange ugentligt og én gang ugentligt, øger hæmoglobin og nedsætter behovet for transfusioner efter den første måneds behandling hos anæmiske cancerpatienter.
English: Additional studies compared the 40 000 IU once-weekly regimen of epoetin alfa with biweekly doses ranging from 80 000 to 120 000 IU subcutaneously.
Danish: I andre studier blev regimet med 40.000 IE epoetin alfa én gang ugentligt sammenlignet med en dosis hver anden uge i intervallet fra 80.000-120.000 IE indgivet subkutant.
English: The liquid needs to come to room temperature.
Danish: Væsken skal opnå stuetemperatur.
English: In the double-blind study, patients were treated with epoetin alfa 600 IU/kg or placebo intravenously once daily every 3 to 4 days over 3 weeks (total 6 doses).
Danish: I det dobbeltblindede studie fik patienterne epoetin alfa 600 IE/kg eller placebo intravenøst én gang dagligt hver 3. til 4. dag i løbet af 3 uger (i alt 6 doser).
English: An inverse relationship between apparent clearance and dose was noted in healthy subjects.
Danish: Hos raske forsøgs-personer sås et omvendt forhold mellem tilsyneladende clearance og dosis.
English: Rare: may affect up to 1 in 1 000 people.
Danish: Sjældne: Forekommer hos op til 1 ud af 1.000 patienter.
English: Early shunt revision and thrombosis prophylaxis by administration of acetylsalicylic acid, for example, is recommended in these patients.
Danish: Til disse patienter anbefales tidlig shunt-revision og tromboseprofylakse med f.eks acetylsalicylsyre.
English: Due to intra-patient variability, occasional individual haemoglobin values for a patient above and below the desired haemoglobin concentration range may be observed.
Danish: På grund af intrapatientvariationer kan der lejlighedsvis observeres individuelle hæmoglobinværdier hos en patient, der er over og under det ønskede koncentrationsinterval.
English: • Severe allergic reaction that may include: o a swollen face, lips, mouth, tongue or throat o difficulty swallowing or breathing o itchy rash (hives).
Danish: • Alvorlig allergisk reaktion, herunder: o Hævelser i ansigt, læberne, munden, tungen eller halsen.
English: Do not remove the syringe's needle cover while allowing it to reach room temperature.
Danish: Fjern ikke sprøjtens nålebeskyttelseshætte, mens stuetemperatur opnås.
English: For cancer patients, iron supplementation (elemental iron 200 to 300 mg/day orally) is recommended if transferrin saturation is below 20%.
Danish: Det anbefales at give jerntilskud (elementært jern 200-300 mg/dag oralt) til cancerpatienter, hvis transferrinmætningen ligger under 20 %.
English: • shortened overall survival and increased deaths attributed to disease progression at 4 months in patients with metastatic breast cancer receiving chemotherapy when administered to achieve a haemoglobin concentration range of 12 to 14 g/dL (7.5 to 8.7 mmol/L),
Danish: • kortere samlet overlevelse og forhøjet dødelighed, der tilskrives sygdomsprogression ved 4 måneder hos patienter med metastatisk brystcancer, som får kemoterapi, når det administeres for at opnå en hæmoglobinkoncentration på 12-14 g/dl (7,5-8,7 mmol/l),
English: Therefore, epoetin zeta should not be used in patients with baseline haemoglobin >13 g/dL (>8.1 mmol/L).
Danish: Epoetin zeta bør derfor ikke anvendes til patienter med en hæmoglobinværdi på > 13 g/dl (>8,1 mmol/l) ved baseline.
English: • Check the syringe, to make sure it is the right dose, has not passed its expiry date, is not damaged, and the liquid is clear and not frozen.
Danish: • Kontrollér sprøjten for at sikre, at det er den rigtige dosis, at udløbsdatoen ikke er overskredet,
English: Chemotherapy-induced anaemia
Danish: Kemoterapi-induceret anæmi
English: HOSPIRA Enterprises B.V. Randstad 22-11
Danish: Randstad 22-11
English: Good sites are the top of the thigh and around the tummy (abdomen)
Danish: Gode steder er den øverste del af låret og på maven, men ikke nær navlen.
English: In paediatric patients the recommended haemoglobin concentration range is between 9.5 g/dL to 11 g/dL (5.9 to 6.8 mmol/L).
Danish: Hos pædiatriske patienter er det anbefalede koncentrationsinterval for hæmoglobin mellem 9,5-11 g/dl (5,9-6,8 mmol/l).
English: Epoetin zeta should be used with caution in patients with epilepsy, history of seizures, or medical conditions associated with a predisposition to seizure activity such as CNS infections and brain metastases.
Danish: Epoetin zeta skal anvendes med forsigtighed til patienter med epilepsi, krampeanfald i anamnesen eller medicinske lidelser forbundet med disponering for krampeanfald såsom infektioner i centralnervesystemet og hjernemetastaser.
English: Chronic renal failure patients being treated with epoetin zeta should have haemoglobin levels measured on a regular basis until a stable level is achieved, and periodically thereafter.
Danish: Patienter med kronisk nyresvigt, som er i behandling med epoetin zeta, skal regelmæssigt have målt hæmoglobin, indtil der opnås et stabilt niveau og derefter med løbende mellemrum.
English: In the single-blind study, patients were treated with epoetin alfa 300 IU/kg or 600 IU/kg or placebo intravenously once daily every 3 to 4 days over 3 weeks (total 6 doses).
Danish: I det enkeltblindede studie fik patienterne epoetin alfa 300 IE/kg eller 600 IE/kg eller placebo intravenøst én gang dagligt hver 3. til 4. dag i 3 uger (i alt 6 doser).
English: erythropoietin suggested that distribution volume was approximately 1.5 to 2 times higher in the preterm neonates than in the healthy adults, and clearance was approximately 3 times higher in the preterm neonates than in healthy adults.
Danish: Et studie med 7 præmature neonatale patienter med meget lav fødselsvægt og 10 raske voksne, som fik intravenøs erythropoietin, tydede på, at fordelingsvolumenet var omtrent 1,5 til 2 gange højere hos de præmature neonatale patienter end hos de raske voksne, og at clearance var omtrent 3 gange højere hos præmature neonatale patienter end hos raske voksne.
English: Median overall survival in the epoetin alfa plus SOC group was 17.8 months compared with 18.0 months in the SOC alone group (HR 1.07, 95% CI: 0.97, 1.18).
Danish: Median samlet overlevelse i gruppen, der blev behandlet med epoetin alfa plus standardbehandling var 17,8 måneder sammenlignet med 18 måneder i gruppen, der alene fik standardbehandling (HR 1,07, 95 % CI: 0,97, 1,18).
English: Each pack contains 1, 4 or 6 pre-filled syringes.
Danish: Hver pakning indeholder 1, 4 eller 6 fyldte injektionssprøjter.
English: If necessary, increase or decrease the dose by 25 IU/kg (3 times per week) until the desired haemoglobin concentration range between 10 g/dL to 12 g/dL (6.2 to 7.5 mmol/L) is achieved (this should be done in steps of at least four weeks).
Danish: Hvis det er nødvendigt, øges eller mindskes dosis med 25 IE/kg (3 gange ugentligt), indtil det tilstræbte koncentrationsinterval for hæmoglobin mellem 10-12 g/dl (6,2-7,5 mmol/l) er opnået (dette bør udføres med mindst 4 ugers interval).
English: Epoetin alfa has been shown to stimulate erythropoiesis in anaemic patients with CRF, including dialysis and pre-dialysis patients.
Danish: Det er vist, at epoetin alfa stimulerer erytropoiesen hos anæmiske patienter med kronisk nyresvigt, herunder såvel dialyse- som prædialysepatienter.
English: Adult haemodialysis patients
Danish: Voksne hæmodialysepatienter
English: Erythroid response during the first 24 weeks of the study was demonstrated by 27/85 (31.8%) of the subjects in the epoetin alfa group compared to 2/45 (4.4%) of the subjects in the placebo group (p<0.001).
Danish: I løbet af de første 24 uger af studiet demonstrerede 27/85 (31,8 %) af patienterne i epoetin alfa gruppen erythroidrespons sammenlignet med 2/45 (4,4 %) af patienterne i placebogruppen (p < 0,001).Alle de responderende patienter var i stratummet med sEPO < 200 mU/ml under screening.
English: Epoetin zeta should be used with caution in patients with porphyria.
Danish: Der bør udvises forsigtighed ved brug af epoetin zeta til patienter med porfyri.
English: This medicinal product contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially ‘sodium free'.
Danish: Dette lægemiddel indeholder mindre end 1 mmol (23 mg) natrium pr. dosis, dvs. det er i det væsentlige natrium-frit.
English: For patients scheduled for major elective orthopaedic surgery, iron supplementation (elemental iron 200 mg/day orally) should be administered throughout the course of epoetin zeta therapy.
Danish: Til patienter, der skal gennemgå større planlagt elektiv ortopædkirurgi, skal der gives jerntilskud (elementært jern 200m/dag oralt) under hele epoetin zetabehandlingen.
English: Currently available data for subcutaneous use of epoetin alfa in these populations are described in section 5.1 but no recommendation on posology can be made.
Danish: De foreliggende data for subkutan brug af epoetin alfa hos disse populationer er beskrevet i pkt.
English: How to use Retacrit
Danish: Sådan skal du bruge Retacrit
English: Detailed information is available on the website of the European Medicines Agency http://www.ema.europa.eu.
Danish: Du kan finde yderligere oplysninger findes på det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu.
English: The mean CL/F for the 150 IU/kg 3 times-per-week and 40 000 IU once-weekly regimens in healthy subjects were 31.2 and 12.6 mL/h/kg, respectively.
Danish: Middelværdierne for CL/F ved regimer på 150 IE/kg 3 gange ugentligt og 40.000 IE en gang ugentligt hos raske forsøgspersoner var henholdsvis 31,2 og 12,6 ml/time/kg.
English: This medicine contains less than 1 mmol sodium (23 mg) per dose, i.e. essentially ‘sodium-free'.
Danish: Denne medicin indeholder mindre end 1 mmol (23 mg) natrium pr. dosis, dvs. den er i det væsentlige natriumfri.
English: • in adults on haemodialysis or peritoneal dialysis.
Danish: hos voksne i hæmodialyse eller peritoneal dialyse.
English: Retacrit should be administered in order to increase haemoglobin to not greater than 11 g/dL (6.8 mmol/L).
Danish: Retacrit skal administreres for at øge hæmoglobin til maksimalt 11 g/dl (6,8 mmol/l).
English: Epoetin alfa was evaluated in an open-label, non-randomised, open dose-range, 52-week clinical study in paediatric CRF patients undergoing haemodialysis.
Danish: Epoetin alfa blev evalueret i et åbent, ikke randomiseret klinisk studie på 52 uger med åbent dosisinterval hos pædiatriske patienter med kronisk nyresvigt, der var i hæmodialyse.
English: In the event of either being observed, discard the medicinal product.
Danish: Hvis du kan se noget af dette, skal lægemidlet bortskaffes.
English: The other ingredients are disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, sodium chloride, calcium chloride dihydrate, polysorbate 20, glycine, leucine, isoleucine, threonine, glutamic acid, phenylalanine, water for injections, sodium hydroxide (pH adjuster), hydrochloric acid (pH adjuster).
Danish: Øvrige indholdsstoffer: dinatriumphosphatdihydrat, natriumdihydrogenphosphatdihydrat, natriumchlorid, calciumchloriddihydrat, polysorbat 20, glycin, leucin, isoleucin, treonin, glutaminsyre, phenylalanin, vand til injektionsvæsker, natriumhydroxid (til justering af pH), saltsyre (til justering af pH).
English: The mean CL/F for the 150 IU/kg, 3-times-per-week and 40 000 IU, once-weekly regimens in the anaemic cancer subjects were 45.8 and 11.3 mL/h/kg, respectively.
Danish: Middelværdierne for CL/F ved regimer på 150 IE/kg 3 gange ugentligt og 40.000 IE en gang ugentligt hos anæmiske forsøgspersoner med cancer var henholdsvis 45,8 og 11,3 ml/time/kg.
English: The AUCs of the respective pharmacodynamic parameters were similar between the 150 IU/kg, 3 times-per-week and 40 000 IU, once-weekly dosing regimens in healthy subjects and also in anaemic cancer subjects.
Danish: AUC for de respektive farmakodynamiske parametre var sammenlignelige for dosisregimer med 150 IE/kg 3 gange ugentligt og 40.000 IE én gang ugentligt hos raske forsøgspersoner og hos anæmiske forsøgspersonerpersoner med cancer.
English: • The usual dose is 600 IU per kilogram bodyweight twice a week.
Danish: • Den sædvanlige dosis er 600 IE pr. kilogram legemsvægt 2 gange om ugen
English: In cancer patients receiving chemotherapy, the 2 to 3 week delay between ESA administration and the appearance of erythropoietin-induced red cells should be taken into account when assessing if epoetin zeta therapy is appropriate (patient at risk of being transfused).
Danish: Ved vurderingen af hvorvidt behandling med epoetin zeta er hensigtsmæssig (patienter i risiko for transfusion) hos cancerpatienter i kemoterapibehandling, bør det tages i betragtning, at der går 2-3 uger fra administration af erythropoietin, til der viser sig erythropoietin-fremkaldte røde blodceller.
English: • Before use, leave the Retacrit syringe to stand until it reaches room temperature.
Danish: • Inden du bruger Retacrit, skal du lade sprøjten opnå stuemperatur.
English: Particular attention should be paid to sudden stabbing migraine-like headaches as a possible warning signal (see section 4.4).
Danish: Det er særligt vigtigt at være opmærksom på pludselige migrænelignende hovedpiner med jag, hvilket kan være et advarselstegn (se pkt.
English: Do not throw away any medicines via wastewater or household waste.
Danish: Af hensyn til miljøet må du må ikke smide medicinrester i afløbet, toilettet eller skraldespanden.
English: If the haemoglobin concentration has increased <1 g/dL (<0.62 mmol/L) and the reticulocyte count has increased <40 000 cells/µL above baseline, response is unlikely and treatment should be discontinued.
Danish: Hvis koncentrationen af hæmoglobin er steget < 1 g/dl (< 0,62 mmol/l), og reticulocyttallet er steget < 40.000 celler/mikrol over baseline, kan respons ikke forventes, og behandling bør seponeres.
English: Yes ≤2 RBC Units ˃2 and ≤4 RBC Units ˃4 RBC Units No one subject did not have sEPO data in the ≥200 mU/ml stratum there were 13 subjects in the epoetin alfa group and 6 subjects in the placebo group
Danish: Ja ≤ 2 RBC enheder ˃ 2 og ≤ 4 RBC enheder ˃ 4 RBC enheder
English: A rise in haemoglobin of greater than 2 g/dL (1.25 mmol/L) over a four week period should be avoided.
Danish: En stigning i hæmoglobin på mere end 2 g/dl (1,25 mmol/l) over en 4-ugers periode bør undgås.
English: • Hold the pre-filled syringe by the body of the syringe with the covered needle pointing upward.
Danish: • Hold den fyldte sprøjte på cylinderen med nålebeskyttelseshætten pegende opad.
English: Hypersensitivity reactions, including cases of rash (including urticaria), anaphylactic reactions, and angioneurotic oedema have been reported (see section 4.4).
Danish: Der foreligger rapporter om overfølsomhedsreaktioner, inklusive tilfælde med udslæt (herunder urticaria), anafylaktiske reaktioner og angioødem (se pkt.
English: Solution for injection in pre-filled syringe (injection).
Danish: Injektionsvæske, opløsning i fyldt injektionssprøjte (injektion).
English: • Take the cover off the syringe by holding the barrel and pulling the cover off carefully without twisting it. Don't push the plunger, touch the needle or shake the syringe.
Danish: • Tag beskyttelsen af sprøjten ved at holde på cylinderen og forsigtig trække hætten af uden at vride den.
English: The median TTP based on IRC-determined PD was 8.0 months in the epoetin alfa plus SOC group and 8.3 months in the SOC group (HR 1.033, 95% CI:
Danish: Mediantid til progression baseret på IRC vurderet sygdomsprogression var 8,0 måneder i gruppen, der blev behandlet med epoetin alfa plus standardbehandling og 8,3 måneder i gruppen, der alene fik standardbehandling (HR 1,033, 95 % CI:
English: The use of epoetin zeta is not recommended in lactating surgical patients participating in an autologous blood predonation programme.
Danish: Epoetin zeta bør ikke anvendes hos ammende kirurgiske patienter, der deltager i en autolog blodprædonation.
English: If the haemoglobin concentration has increased by at least 1 g/dL (0.62 mmol/L) or the reticulocyte count has increased ≥ 40 000 cells/µL above baseline after 4 weeks of treatment, the dose should remain at 150 IU/kg 3 times per week or 450 IU/kg once weekly.
Danish: Hvis koncentrationen af hæmoglobin er steget med mindst 1 g/dl (0,62 mmol/l), eller reticulocyttallet er steget ≥ 40.000 celler/mikrol over baseline efter 4 ugers behandling, bør der fortsættes med dosis på 150 IE/kg 3 gange ugentligt eller 450 IE/kg 1 gang ugentligt.
English: Adult peritoneal dialysis patients
Danish: Voksne peritonealdialysepatienter
English: • Dispose of your used syringe in a sharps container.
Danish: • Kassér den brugte sprøjte i en kanylebeholder.
English: • The starting dose is 450 IU per kilogram bodyweight once a week.
Danish: • Startdosis er 450 IE pr. kilogram legemsvægt en gang om ugen.
English: Disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, sodium chloride, calcium chloride dihydrate, polysorbate 20, glycine, leucine, isoleucine, threonine, glutamic acid, phenylalanine, water for injections, sodium hydroxide (pH adjuster), hydrochloric acid (pH adjuster).
Danish: Dinatriumfosfatdihydrat, natriumdihydrogenfosfatdihydrat, natriumchlorid, kalciumkloriddihydrat, polysorbat 20, glycin, leucin, isoleucin, threonin, glutaminsyre, phenylalanin, vand til injektioner, natriumhydroxid (til justering af pH-værdien), saltsyre (til justering af pH-værdien).
English: An increased incidence of thrombotic vascular events (TVEs) has been observed in patients receiving ESAs (see section 4.4).
Danish: Der er observeret en øget forekomst af trombotiske vaskulære hændelser (TVE'er) hos patienter, der får ESA'er (se pkt.
English: Chronic renal failure
Danish: Kronisk nyresvigt
English: Retacrit should be administered as a subcutaneous injection.
Danish: Retacrit skal administreres subkutant.
English: Similar rates of rise of haematocrit were noted when epoetin alfa was administered by either route.
Danish: Der observeredes tilsvarende rater for stigning i hæmatokrit, når epoetin alfa blev administreret enten intravenøst eller subkutant.
English: Serum electrolytes should be monitored in chronic renal failure patients.
Danish: Der skal måles serumelektrolytter hos patienter med kronisk nyresvigt.
English: Do not administer Retacrit by intravenous infusion or in conjunction with other medicinal product solutions (please refer to section 6.6 for further information).
Danish: Retacrit må ikke administreres som intravenøs infusion eller sammen med andre lægemiddelopløsninger (se pkt.
English: The median time to progression (TTP) based on investigator-determined progressive disease (PD) was 7.5 months in the epoetin alfa plus SOC group and 7.5 months in the SOC group (HR 1.099, 95% CI: 0.998, 1.210).
Danish: Mediantid til progression baseret på investigators vurdering af sygdomsprogression var 7,5 måneder i gruppen, der blev behandlet med epoetin alfa plus standardbehandling og 7,5 måneder i gruppen, der alene fik standardbehandling (HR 1,099, 95 % CI: 0,998, 1,210).
English: While on Retacrit, some people need medicines to reduce the risk of blood clots.
Danish: Visse personer har behov for at tage medicin, der nedsætter risikoen for blodpropper, mens de bruger Retacrit.
English: Some patients with more extended dosing intervals (greater than once weekly) of epoetin zeta may not maintain adequate haemoglobin levels (see section 5.1) and may require an increase in epoetin zeta dose.
Danish: 5.1) ved mere forlængede dosisintervaller (længere end en uge) for epoetin zeta, og en forøgelse af epoetindosis kan være nødvendig.
English: • Flu-like symptoms, such as headache, aches and pains in the joints, feeling of weakness, chills,
Danish: • Influenzalignende symptomer, f.eks hovedpine, ledsmerter, mathed, kulderystelser, træthed og svimmelhed.
English: Paediatric population with chronic renal failure on haemodialysis
Danish: Pædiatrisk population med kronisk nyresvigt i hæmodialyse
English: • Retacrit is used to treat symptomatic anaemia caused by kidney disease
Danish: • Retacrit anvendes til at behandle symptomgivende blodmangel forårsaget af nyresygdom hos børn i hæmodialyse.
English: Retacrit should be administered to patients with symptomatic anaemia (e.g. haemoglobin concentration ≤10 g/dL (6.2 mmol/L)).
Danish: Retacrit skal administreres til patienter med symptomatisk anæmi (f.eks. hæmoglobinkoncentration ≤ 10 g/dl (6,2 mmol/l)).
English: If after an additional 4 weeks of therapy at 300 IU/kg 3 times per week, the haemoglobin concentration has increased ≥ 1 g/dL (≥0.62 mmol/L) or the reticulocyte count has increased ≥40 000 cells/µl, the dose should remain at 300 IU/kg 3 times per week.
Danish: Hvis koncentrationen af hæmoglobin efter yderligere 4 ugers behandling med 300 IE/kg 3 gange ugentligt er steget ≥ 1 g/dl (0,62 mmol/l), eller reticulocyttallet er steget med ≥ 40.000 celler/mikrol, skal dosis holdes på 300 IE/kg 3 gange om ugen.
English: • The recommended dose is 600 IU per kilogram bodyweight once a week.
Danish: • Den anbefalede dosis er 600 IE pr. kilogram legemsvægt 1 gang om ugen.
English: The safety of epoetin zeta has not been established in patients with hepatic dysfunction.
Danish: Epoetin alfas sikkerhed er ikke blevet klarlagt hos patienter med leverdysfunktion
English: Retacrit 8 000 IU
Danish: Retacrit 8.000 IE
English: 30 000 IU/0.75 ml
Danish: 30.000 IE/0,75 ml
English: A sustained haemoglobin level of greater than 12 g/dL (7.5 mmol/L) should be avoided.
Danish: Et vedvarende hæmoglobinniveau over 12 g/dl (7,5 mmol/l) bør undgås.
English: Respiratory tract congestion, which includes events of upper respiratory tract congestion, nasal congestion and nasopharyngitis, have been reported in studies with extended interval dosing in adult patients with renal insufficiency not yet undergoing dialysis.
Danish: I studier med længere dosisinterval er der rapporteret om tilstoppede øvre luftveje som forstoppet næse og nasopharyngitis hos voksne patienter med nyreinsufficiens, der endnu ikke er i dialyse.
English: If the haemoglobin concentration is increasing by more than 2 g/dL (1.25 mmol/L) per month, or if the haemoglobin concentration level exceeds 12 g/dL (7.5 mmol/L), reduce the Retacrit dose by about 25 to 50%.
Danish: Hvis koncentrationen af hæmoglobin stiger med mere end 2 g/dl (1,25 mmol/l) pr. måned, eller hvis koncentrationen af hæmoglobin overstiger 12 g/dl (7,5 mmol/l), skal dosis af Retacrit reduceres med ca. 25-50 %.
English: Retacrit 20 000 IU
Danish: Retacrit 20.000 IE