FrancophonIA/ELRC3.0 huggingface dataset:
English: Co-administration of the proton pump inhibitor omeprazole and PROCYSBI in vivo showed no effects on cysteamine bitartrate exposure.
Danish: In vivo koadministration af protonpumpehæmmeren omeprazol havde ingen indvirkning på eksponeringen for cysteaminbitartrat.
English: Severe allergic reaction (seen uncommonly): Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of face, lips, tongue, or throat.
Danish: Kontakt straks lægen eller sundhedspersonalet, hvis du oplever en eller flere af nedenstående bivirkninger - du behøver muligvis øjeblikkelig lægehjælp: Svær allergisk reaktion (ikke almindelig): Søg akut lægehjælp ved nogen af disse tegn på en allergisk reaktion: nældefeber, vejrtrækningsbesvær, hævelse af ansigt, læber, tunge eller hals.
English: 400 mL white HDPE bottle containing 250 capsules with one 2-in-1 desiccant cylinder and two oxygen absorber cylinders, with a child resistant polypropylene closure.
Danish: 400 ml hvid HDPE-flaske med børnesikret lukke af polypropylen indeholdende 250 kapsler og en 2-i1-cylinder med tørremiddel og to iltabsorberende cylindre.
English: Cysteamine therapy must be initiated promptly once the diagnosis is confirmed (i.e., increased WBC cystine) to achieve maximum benefit.
Danish: Behandlingen med cysteamin skal begynde, så snart diagnosen er bekræftet (dvs. forhøjet indhold af cystin i leukocytterne) for at patienten skal opnå størst mulig fordel af behandlingen.
English: Report any changes to your doctor.
Danish: Kontakt lægen, hvis der er forandringer.
English: Each gastro-resistant hard capsule contains 25 mg or 75 mg of cysteamine.
Danish: Hver enterokapsel indeholder 25 mg eller 75 mg cysteamin.
English: CNS symptoms such as seizures, lethargy, somnolence, depression, and encephalopathy have been associated with cysteamine.
Danish: CNS-symptomer såsom krampeanfald, letargi, somnolens, depression og encefalopati er blevet sat i forbindelse med cysteamin.
English: WBC cystine level (LS Mean ± SE) in nmol hemicystine/mg protein*
Danish: Cystinindhold i leukocytter (mindste kvadraters gennemsnit ± standardfejl) i nmol hemicystin/mg protein*
English: Effects on fertility have been seen in animal studies (see section 5.3).
Danish: Dyreforsøg har vist påvirkning af fertiliteten (se pkt.
English: Individuals with cystinosis have elevations of WBC cystine above 2 nmol hemicystine/mg protein.
Danish: Hos personer med cystinose er leukocytternes cystinindhold forhøjet til over 2 nmol hemicystin/mg protein.
English: Your doctor will monitor you for benign intracranial hypertension (or pseudotumor cerebri (PTC)) and/or swelling of the optic nerve (papilledema) associated with cysteamine treatment.
Danish: Lægen vil overvåge dig for godartet forhøjet intrakranielt tryk (falsk hjernetumor) og/eller hævelse af synsnerven (papilødem), som forekommer ved behandling med cysteamin.
English: Stomach and intestinal (gastrointestinal) problems: Patients taking cysteamine have developed ulcers and bleeding.
Danish: Problemer med mave-tarmsystemet: Patienter i behandling med cysteamin har fået mavesår og blødning.
English: The MAH shall provide an educational pack targeting all physicians who are expected to prescribe PROCYSBI prior to the launch.
Danish: Indehaveren af markedsføringstilladelsen udleverer før markedsføringen et sæt informationsmateriale til alle læger, der forventes at ordinere PROCYSBI.
English: What PROCYSBI contains
Danish: PROCYSBI indeholder:
English: Uncommon: Gastrointestinal ulcer Common: Skin odour abnormal, rash
Danish: Ikke almindelig: Gastrointestinalt ulcus Almindelig: Unormal hudlugt, udslæt
English: Central nervous system symptoms: Some patients taking cysteamine have developed seizures, depression, and become too sleepy (excessive sleepiness).
Danish: Symptomer fra centralnervesystemet: Nogle patienter har ved behandling med cysteamin fået krampeanfald og depression og tendens til stærk søvnighed.
English: Patients with poorer tolerability still receive significant benefit if white blood cell cystine levels are below 2 nmol hemicystine/mg protein (when measured using the mixed leukocyte assay).
Danish: Patienter med ringe tolerabilitet vil stadig have væsentlig fordel af at få sænket leukocytternes cystinindhold til under 2 nmol hemicystin/mg protein (målt med den blandede leukocytanalyse).
English: Printing ink shellac povidone K-17 titanium dioxide (E171)
Danish: Trykfarve shellac povidon K-17 titaniumdioxid (E171)
English: o In the printing ink: shellac, povidone (K-17), titanium dioxide (E171).
Danish: o I trykfarven: shellac, povidon (K-17), titaniumdioxid (E171).
English: It is important to dose PROCYSBI in relation to food intake in a consistent and reproducible way over time (see section 5.2) In paediatric patients who are at risk of aspiration, aged approximately 6 years and under, the hard capsules should be opened and the content sprinkled on food or liquid listed below.
Danish: 5.2) Til pædiatriske patienter med risiko for aspiration (under seks år) åbnes de hårde kapsler, og indholdet drysses på mad eller drikke som angivet nedenfor.
English: The mixture must be eaten within 2 hours after preparation and must be refrigerated from the time of preparation to the time of administration.
Danish: Blandingen skal indtages senest to timer efter at den er tilberedt, og skal opbevares nedkølet fra tilberedningen til indtagelsen.
English: In order for this medicine to work correctly, you must do the following: - Swallow the whole capsule with an acidic drink (such as orange juice or any acidic juice) or water.
Danish: Overhold følgende for at PROCYSBI skal virke korrekt: - Slug hele kapslen med en sur drik (appelsinjuice eller anden sur juice) eller vand.
English: If skin or bone abnormalities appear, the dose of cysteamine should be reduced or stopped.
Danish: Hud- eller knogleforandringer bør medføre dosisreduktion eller seponering af cysteamin.
English: There have been reports of serious skin lesions in patients treated with high doses of immediaterelease cysteamine bitartrate or other cysteamine salts that have responded to cysteamine dose reduction.
Danish: Der er beskrevet tilfælde, hvor dosisreduktion af cysteamin medførte bedring af alvorlige hudlæsioner hos patienter, der var behandlet med høje doser af cysteaminbitartrat med hurtig udløsning eller med andre salte af cysteamin.
English: PROCYSBI 75 mg hard capsule
Danish: PROCYSBI 75 mg hård kapsel
English: Normal individuals and persons heterozygous for cystinosis have white blood cell cystine levels of < 0.2 and usually below 1 nmol hemicystine/mg protein, respectively, when measured using the mixed leukocyte assay.
Danish: Leukocytternes cystinindhold er < 0,2 nmol hemicystin/mg protein hos normale personer, og sædvanligvis under 1 nmol hemicystin/mg protein hos personer, som er heterozygote for cystinose, målt med den blandede leukocytanalyse.
English: Capsule shell gelatin titanium dioxide (E171) indigo carmine (E132)
Danish: Kapselskal gelatine titaniumdioxid (E171) indigocarmin (E132)
English: Discard 30 days after opening the foil seal.
Danish: Skal kasseres 30 dage efter anbrud af folielukningen.
English: If fasting during this period is not possible, it is acceptable to eat only a small amount ( 100 grams) of food (preferentially carbohydrates) during the hour before and after PROCYSBI administration.
Danish: Patienter, der ikke kan faste så længe, bør nøjes med et lille måltid (100 gram) (fortrinsvis kulhydrater) i tidsrummet fra en time før til en time efter administration af PROCYSBI.
English: Dermatological
Danish: Dermatologiske risici
English: No carcinogenic studies have been conducted with cysteamine bitartrate gastro-resistant hard capsules.
Danish: Der er ikke udført karcinogenicitetsundersøgelser med cysteaminbitartrat som enterokapsler.
English: o In the capsule shell: gelatin, titanium dioxide (E171), indigo carmine (E132).
Danish: o I kapselskallen: gelatine, titaniumdioxid (E171), indigocarmin (E132).
English: GI ulceration and bleeding have been reported in patients receiving immediate-release cysteamine bitartrate.
Danish: Der er rapporteret gastrointestinal ulceration og blødning ved behandling med cysteaminbitartrat med hurtig udløsning.
English: PROCYSBI 25 mg hard capsule
Danish: PROCYSBI 25 mg hård kapsel
English: Consult your child's doctor for complete directions.
Danish: Få nærmere vejledning hos den læge, der behandler barnet.
English: If you are allergic to cysteamine (also known as mercaptamine) or any of the other ingredients of this medicine (listed in section 6).
Danish: Tag ikke PROCYSBI: hvis du er allergisk over for cysteamin (der også kaldes mercaptamin) eller et af de øvrige indholdsstoffer i PROCYSBI (angivet i afsnit 6) hvis du er allergisk over for penicillamin hvis du ammer
English: In some patients, the skin lesions on elbows regressed after immediate-release cysteamine dose reduction (see section 4.4).
Danish: Hudforandringerne på albuerne svandt hos nogle patienter ved dosisreduktion af cysteamin med hurtig udløsning (se pkt.
English: Abnormal liver function or reduced white blood cell count (leukopenia) can occur with use of cysteamine.
Danish: Cysteamin kan give abnorm leverfunktion eller nedsat antal hvide blodlegemer (leukopeni).
English: SPECIAL STORAGE CONDITIONS Store in a refrigerator.
Danish: SÆRLIGE OPBEVARINGSBETINGELSER Opbevares i køleskab (2 °C - 8 °C).
English: How to take PROCYSBI
Danish: Sådan skal du tage PROCYSBI
English: Discard Date:
Danish: Dato for bortskaffelse:
English: Do not crush or chew capsules or capsule contents.
Danish: Kapsler eller kapselindhold må ikke knuses eller tygges.
English: Gently stir the contents into the soft food, creating a mixture of cysteamine granules and the soft food.
Danish: Indholdet omrøres forsigtigt, så cysteamin-kornene blandes op i den bløde mad.
English: Stomach and intestinal ulcers and bleeding can occur in patients receiving cysteamine (see section 4).
Danish: Behandling med cysteamin kan medføre mavesår, tarmsår og blødning (se afsnit 4).
English: The cysteamine dose can be increased to a maximum of 1.95 g/m2/day to achieve this level.
Danish: For at nå dette niveau kan cysteamindosis øges til højst 1,95 g/m2/dag.
English: The use of doses higher than 1.95 g/m2/day is not recommended.
Danish: En dosering over 1,95 g/m2/dag frarådes.
English: • Breast-feeding.
Danish: • Amning.
English: Cysteamine (mercaptamine bitartrate)
Danish: Cysteamin (mercaptaminbitartrat)
English: Bone disorders reported were genu valgum, leg pain and hyperextensive joints, osteopenia, compression fractures, and scoliosis.
Danish: De indberettede knogleforandringer var genu valgum, smerter i benene, hypermobile led, osteopeni, kompressionsbrud og skoliose.
English: Frequency: adverse reaction
Danish: Hyppighed: bivirkning
English: Specific studies with cysteamine did not show any mutagenic effects in the Ames test or any clastogenic effect in the mouse micronucleus test. A bacterial reverse mutation assay study (“Ames test”) was performed with the cysteamine bitartrate used for PROCYSBI and cysteamine bitartrate did not show any mutagenic effects in this test.
Danish: Der sås ingen mutagene virkninger i en undersøgelse med bakteriel tilbagemutation (“Ames test”) af det cysteaminbitartrat, der anvendes til PROCYSBI.
English: Skin lesions, bone lesions, and joint problems: Treatment with high doses of cysteamine can cause skin lesions to develop.
Danish: Ikke almindelige bivirkninger (forekommer hos indtil 1 ud af 100 behandlede): Hudforandringer, knogleforandringer og ledproblemer: Behandling med høje doser cysteamin kan medføre hudforandringer.
English: The use of doses higher than 1.95 g/m2/day is not recommended (see section 4.2).
Danish: En dosering over 1,95 g/m2/dag frarådes (se pkt.
English: However, due to the results of animal studies in breast-feeding females and neonates (see section 5.3), breast-feeding is contra-indicated in women taking PROCYSBI (see section 4.3).
Danish: 5.3) er amning imidlertid kontraindiceret hos kvinder i behandling med PROCYSBI (se pkt.
English: PROCYSBI 75 mg is presented as blue gastro-resistant hard capsules.
Danish: PROCYSBI, 75 mg, leveres som blå, hårde enterokapsler.
English: • The risk of teratogenicity and relevant risk minimisation advice: Women of childbearing potential should be informed about the risk of teratogenicity; For women of child-bearing potential a negative pregnancy test should be confirmed before starting treatment;
Danish: fødedygtige kvinder skal informeres om risikoen for teratogenicitet for fødedygtige kvinder skal der foreligge en negativ graviditetstest før påbegyndelse af behandlingen fødedygtige kvinder skal instrueres i at bruge hensigtsmæssig antikonception under behandlingen fødedygtige kvinder skal instrueres i at kontakte den behandlende læge, hvis de bliver gravide under behandlingen
English: Light blue size 0 hard capsules imprinted “75 mg” in white ink and a dark blue cap imprinted with “PRO” in white ink.
Danish: Lyseblå hårde kapsler, størrelse 0, med påskriften “75 mg” med hvid trykfarve, og mørkeblå overdel med påtrykt ”PRO”-logo med hvid trykfarve.
English: Each hard capsule contains 75 mg of cysteamine (as mercaptamine bitartrate).
Danish: Hver hård kapsel indeholder 75 mg cysteamin (som mercaptaminbitartrat).
English: Light blue size 3 hard capsules imprinted “25 mg” in white ink and a light blue cap imprinted with “PRO” in white ink.
Danish: Lyseblå hårde kapsler, størrelse 3, med påskriften “25 mg” med hvid trykfarve, og lyseblå overdel med påtrykt ”PRO”-logo med hvid trykfarve.
English: Each hard capsule contains 25 mg of cysteamine (as mercaptamine bitartrate).
Danish: Hver hård kapsel indeholder 25 mg cysteamin (som mercaptaminbitartrat).
English: Please keep the three cylinders in each bottle during the use of the bottle.
Danish: Alle 3 cylindre skal forblive i flasken under anvendelsen.
English: For example the therapeutic goal is to maintain a WBC cysteine level < 1 nmol hemicystine/mg protein (when measured using the mixed leukocyte assay), 30 min after dosing For patients adherent to a stable dose of PROCYSBI, and who do not have easy access to an adequate facility for measuring their WBC cystine, the goal of therapy should be to maintain plasma cysteamine concentration > 0.1 mg/L, 30 min after dosing.
Danish: For de patienter, der får en stabil dosis af PROCYSBI og ikke har let adgang til at få målt de hvide blodlegemers (leukocytter) cystinindhold, skal behandlingen sigte mod, at cysteamin i plasma holdes > 0,1 mg/l 30 minutter efter doseringen.
English: The dark blue cap is imprinted with “PRO” in white ink and the light blue body is imprinted with “75 mg” in white ink.
Danish: Den mørkeblå kapseloverdel er påtrykt ”PRO”-logoet med hvid trykfarve, og underdelen er påtrykt “75 mg” med hvid trykfarve.
English: What PROCYSBI is and what it is used for What you need to know before you take PROCYSBI How to take PROCYSBI
Danish: Det skal du vide, før du begynder at tage PROCYSBI Sådan skal du tage PROCYSBI Bivirkninger
English: Intact capsules of PROCYSBI should not be administered to children under the age of approximately 6 years due to risk of aspiration (see section 4.2).
Danish: 4.2) bør hele PROCYSBI hårde kapsler ikke gives til børn under ca. 6 år.
English: Symptoms such as seizures, tiredness, sleepiness, depression, and brain disorders (encephalopathy) can occur with cysteamine.
Danish: Cysteamin kan give symptomer såsom krampeanfald, træthed, svimmelhed, depression og hjernesygdom (encefalopati).
English: If you take more PROCYSBI than you should
Danish: Hvis du har taget for meget PROCYSBI
English: ANNEX 1 SUMMARY OF PRODUCT CHARACTERISTICS
Danish: BILAG I PRODUKTRESUMÉ
English: Please keep the two cylinders in each bottle during the use of the bottle.
Danish: Begge cylindre skal forblive i flasken under anvendelsen.
English: 4.6 Fertility, pregnancy and lactation
Danish: 4.6 Fertilitet, graviditet og amninghttp://en.wikipedia.org/wiki/Lactation
English: Please keep the cylinders in each bottle during the use of the bottle.
Danish: Alle cylindre skal forblive i flasken under anvendelsen.
English: To get the most benefit from this medicine, try to avoid meals and dairy products for at least 1 hour before and 1 hour after PROCYSBI dosing.
Danish: Du skal prøve at undgå måltider og mejeriprodukter mindst 1 time før og 1 time efter doseringen med PROCYSBI for at få størst mulig fordel af lægemidlet.
English: Each bottle contains three plastic cylinders used for additional moisture and air protection.
Danish: Hver flaske indeholder tre plastikcylindre til ekstra beskyttelse mod fugt og luft.
English: bone fragility hair discolouration fits nervousness hallucination effect on the kidney manifested by swelling of the extremities and weight gain
Danish: Ikke almindelige bivirkninger: smerter i benene skoliose (sideværts skævhed af rygsøjlen) knogleskørhed misfarvet hår krampeanfald nervøsitet hallucinationer nyrepåvirkning, der viser sig ved hævede arme og ben og vægtøgning
English: Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
Danish: Brug af anden medicin sammen med PROCYSBI Fortæl det altid til lægen eller apotekspersonalet, hvis du tager anden medicin eller har gjort det for nylig.
English: Each bottle contains two plastic cylinders used for additional moisture and air protection.
Danish: Hver flaske indeholder to plastikcylindre til ekstra beskyttelse mod fugt og luft.
English: The light blue cap is imprinted with “PRO” in white ink and the light blue body is imprinted with “25 mg” in white ink.
Danish: Den lyseblå kapseloverdel er påtrykt ”PRO”-logoet med hvid trykfarve, og underdelen er påtrykt “25 mg” med hvid trykfarve.
English: What PROCYSBI looks like and contents of the pack PROCYSBI 25 mg is presented as blue gastro-resistant hard capsules.
Danish: PROCYSBI, 25 mg, leveres som blå, hårde enterokapsler.
English: PHARMACEUTICAL FORM AND CONTENTS Gastro-resistant hard capsule 60 capsules
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) Enterokapsler, hårde
English: Serious skin lesions can occur in patients treated with high doses of cysteamine.
Danish: Høje doser af cysteamin kan medføre alvorlige skader på huden.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each capsule contains 25 mg of cysteamine (as mercaptamine bitartrate).
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver kapsel indeholder 25 mg cysteamin (som mercaptaminbitartrat).
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each capsule contains 75 mg of cysteamine (as mercaptamine bitartrate).
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver kapsel indeholder 75 mg cysteamin (som mercaptaminbitartrat).
English: In genotoxicity studies published for cysteamine, induction of chromosome aberrations in cultured eukaryotic cell lines has been reported.
Danish: I publicerede undersøgelser med cysteamin er beskrevet kromosomforandringer i dyrkede eukaryote cellelinier, men specifikke undersøgelser med cysteamin viste hverken mutagene effekter ved Ames test eller klastogene effekter i mikronucleustest hos mus.
English: Common: Asthenia
Danish: Meget almindelig: Anoreksi
English: NAME OF THE MEDICINAL PRODUCT PROCYSBI 75 mg gastro-resistant hard capsules cysteamine
Danish: LÆGEMIDLETS NAVN PROCYSBI, enterokapsler, hårde, 75 mg cysteamin
English: NAME OF THE MEDICINAL PRODUCT PROCYSBI 25 mg gastro-resistant hard capsules cysteamine
Danish: LÆGEMIDLETS NAVN PROCYSBI, enterokapsler, hårde, 25 mg cysteamin
English: Benign intracranial hypertension, also called pseudotumor cerebri, has been reported with cysteamine use.
Danish: Cysteamin kan medføre godartet forhøjet intrakranielt tryk, også kaldet falsk hjernesvulst.
English: Administering through feeding tubes
Danish: Administration gennem sonde
English: Tell your doctor or nurse straight away if you notice any of the following side effects - you may need urgent medical treatment:
Danish: - Kontakt lægen eller apotekspersonalet, hvis du får bivirkninger, herunder bivirkninger, som ikke er nævnt her.
English: Manufacturer Chiesi Farmaceutici S.p.A.
Danish: Chiesi Pharmaceuticals B.V.
English: PROCYSBI 25 mg gastro-resistant hard capsules PROCYSBI 75 mg gastro-resistant hard capsules
Danish: PROCYSBI, enterokapsler, hårde, 25 mg PROCYSBI, enterokapsler, hårde, 75 mg
English: were randomized.
Danish: Enterokapsel, hård.
English: Other intestinal symptoms including nausea, vomiting, anorexia and stomach ache can occur with cysteamine.
Danish: Cysteamin kan give andre symptomer fra tarmene såsom kvalme, opkastning, appetitløshed og mavepine.
English: These studies were conducted at least 25 years ago.
Danish: Disse undersøgelser er mindst 25 år gamle.
English: Product name INN
Danish: Produktnavn INN
English: Susceptibility tests with isolates outside of the EU were submitted.
Danish: Der blev forelagt følsomhedstest med isolater uden for EU.
English: ATCvet Code: QJ01MA90.
Danish: ATCvet-kode: QJ01MA90.
English: Therefore, there is justification to have a second-line treatment available.
Danish: Der er derfor berettiget at have rådighed over en andetvalgsbehandling.
English: A margin of at least five times the recommended dose was safe.
Danish: En margin på mindst fem gange den anbefalede dosis var uden risiko.
English: Decreased susceptibility varied from approximately 10-50%.
Danish: Andelen med nedsat følsomhed varierede mellem 10 og 50 %.
English: The following conditions should be fulfilled by all marketing authorisation holders (see annex I):
Danish: Følgende betingelser skal opfyldes af alle indehavere af markedsføringstilladelsen (se bilag I):
English: These aspects include:
Danish: Disse aspekter er:
English: administration of the same dose rate.
Danish: stødvis administration af samme dosering.
English: In both species, the available data are rather variable in both quality and outcome.
Danish: For begge arter er de foreliggende data ret svingende både i kvalitet og udfald.
English: The paper by de Jong et al6, 2012, quotes data from the EASSA collected from EU countries.
Danish: Artiklen af de Jong et al6, 2012, citerer data fra EASSA indsamlet i EU-lande.
English: Romania CEVA SANTE ANIMALE ZI Très le Bois - BP 372
Danish: Rumænien CEVA SANTE ANIMALE ZI Très le Bois - BP 372
English: Ilfov, Romania
Danish: Ilfov, Rumænien
English: Add, to all products: 4.4 Special warnings for each target species
Danish: For alle produkter tilføjes: 4.4 Særlige advarsler for hver enkelt dyreart
English: This dose rate controlled the signs of disease.
Danish: Denne dosering kontrollerede sygdomstegnene.
English: The field studies are more than 20 years old and are limited in their reporting.
Danish: Feltundersøgelserne er mere end 20 år gamle, og rapporteringen er begrænset.
English: The paper states that the high values for 20052006 were due to the high level of resistance in Spain (24%), which was not included in reports for 1999-2000.
Danish: Rapporten angiver, at de høje værdier for 2005-2006 skyldtes det høje resistensniveau i Spanien (24 %), som ikke indgik i indberetningerne for 1999-2000.
English: Although methods cannot be directly compared, there is evidence of reduced susceptibility emerging over time.
Danish: Skønt metoderne ikke kan sammenlignes direkte, viser der sig efterhånden tegn på nedsat følsomhed.
English: The abovementioned data should be provided to the CVMP for assessment not later than 3 years after the Commission Decision on this referral procedure.
Danish: Ovenstående data skal forelægges CVMP til vurdering senest 3 år efter Kommissionens beslutning om denne indbringelsesprocedure.
English: Applicant/marketing authorisation holder
Danish: Ansøger/indehaver af markedsføringstilladelse
English: The bibliographic data are also supportive of the longer withdrawal periods.
Danish: De længere tilbageholdelsestider støttes også af de bibliografiske data.
English: If no clinical improvement is achieved within 2-3 days, alternative antimicrobial therapy should be considered based on susceptibility testing.
Danish: Hvis der ikke opnås klinisk bedring i løbet af 2-3 dage, bør anden antimikrobiel behandling baseret på følsomhedsbestemmelse overvejes.