FrancophonIA/ELRC3.0 huggingface dataset:
English: A 6-week, randomised, study of lithium and SEROQUEL XR versus placebo and SEROQUEL XR in adult patients with acute mania indicated that the combination of SEROQUEL XR with lithium leads to more adverse events (63% versus 48% in SEROQUEL XR in combination with placebo).
Maltese: f'pazjenti adulti b'manija akuta indika li l-kombinazzjoni ta' SEROQUEL XR ma' lithium twassal għal aktar avvenimenti avversi (63% kontra 48% f'SEROQUEL XR f'kombinazzjoni ma' plaċebo).
English: Quetiapine is extensively metabolised by the liver.
Maltese: Quetiapine jiġi metabolizzat b'mod estensiv mill-fwied.
English: Mean change among patients who had this increase was 41.7 mg/dL (≥1.07 mmol/L).
Maltese: 41.7 mg/dL (≥1.07 mmol/L).
English: The pharmacokinetics of quetiapine and norquetiapine are linear across the approved dosing range.
Maltese: Il-farmakokinetika ta' quetiapine u norquetiapine huma lineari fil-medda ta' dożaġġ approvat.
English: Seroquel XR 50 mg, 150 mg, 200 mg, 300 mg, 400 mg prolonged-release tablets quetiapine
Maltese: Il-pilloli Seroquel XR fihom 50 mg, 150 mg, 200 mg, 300 mg jew 400 mg ta' quetiapine (bħala quetiapine fumarate).
English: The average molar dose fraction of free quetiapine and the active human plasma metabolite norquetiapine is <5% excreted in the urine.
Maltese: Il frazzjoni medja tad-doża molari ta' quetiapine ħieles u l-metabolit attiv fil-plasma umana norquetiapine jiġi eliminat <5% fl-awrina.
English: Seroquel was administered twice-daily totalling 400 mg to 800 mg a day as combination therapy to lithium or valproate.
Maltese: Seroquel ingħata darbtejn kuljum b'total ta' 400 mg sa 800 mg kuljum bħala terapija kkombinata ma' lithium jew valproate .
English: There is no specific antidote to quetiapine.
Maltese: M'hemmx antidotu speċifiku għal quetiapine.
English: Do not take Seroquel :
Maltese: Tieħux Seroquel :
English: 10 blisters of 5 tablets
Maltese: 10 folji ta' 5 pilloli
English: • If you are taking any of the following medicines: - some medicines for HIV - azole medicines (for fungal infections) - erythromycin or clarithromycin (for infections) - nefazodone (for depression)
Maltese: - mediċini azole (għall-infezzjonijiet fungali) - erythromycin jew clarithromycin (għall-infezzjonijiet) - nefazodone (għad-dipressjoni)
English: Agranulocytosis
Maltese: Il-Ġreċja
English: 6.5 Nature and contents of container Polychlorotrifluoroethylene and polyvinylchloride with aluminium blister
Maltese: Polychlorotrifluoroethylene u polyvinylchloride b'folja tal-aluminju
English: In a 6-week, randomised, study of lithium and SEROQUEL XR versus placebo and SEROQUEL XR in adult patients with acute mania, a higher incidence of extrapyramidal related events (in particular tremor), somnolence, and weight gain were observed in the lithium add-on group compared to the placebo add-on group (see section 5.1).
Maltese: Fi studju randomizzat ta' 6 ġimgħat ta' lithium u SEROQUEL XR kontra plaċebo u SEROQUEL XR f'pazjenti adulti b'manija akuta, kienet osservata inċidenza ogħla ta' avvenimenti ekstrapiramidali relatati (b'mod partikulari rogħda), ngħas, u żieda fil-piż fil-grupp li kellu lithium miżjud meta mqabbla mal-grupp li kellu plaċebo miżjud (ara sezzjoni 5.1).
English: See Section 5.1
Maltese: Ara Sezzjoni 5.1
English: The total daily dose for the first four days of therapy is 50 mg (Day 1), 100 mg (Day 2), 200 mg (Day 3) and 300 mg (Day 4).
Maltese: terapija hija ta' 50 mg (Jum 1), 100 mg (Jum 2), 200 mg (Jum 3) u 300 mg (Jum 4).
English: Hyponatraemia 19, Diabetes Mellitus
Maltese: Iponatremja Dijabete Mellitus
English: The mean clearance of quetiapine in the elderly is approximately 30 to 50% lower than that seen in adults aged 18 to 65 years.
Maltese: It-tneħħija medja ta' quetiapine fl-anzjani hija ta' madwar 30 sa 50% aktar baxxa minn dik li dehret f'adulti bejn it-18 u l-65 sena.
English: Table 1 ADRs associated with quetiapine therapy
Maltese: KLINIKU 4.1 Indikazzjonijiet terapewtiċi
English: Orthostatic hypotension:
Maltese: Pressjoni Baxxa Ortostatika:
English: • Breakdown of muscle fibers and pain in muscles (rhabdomyolysis).
Maltese: • Sensazzjonijiet spjaċevoli fir-riġlejn (imsejħa wkoll sindromu tar-riġlejn irrikwieti).
English: In the mania study, the difference in LS mean change from baseline in YMRS total score (active minus placebo) was -5.21 for Seroquel 400 mg/day and -6.56 for Seroquel 600 mg/day.
Maltese: Fl-istudju fuq manija, id-differenza fil-bidla medja fl-LS mil-linja bażi fil-punteġġ totali fuq YMRS (attiv li minnu tnaqqas il-plaċebo) kienet ta' -5.21 għal Seroquel 400 mg/kuljum u ta' -6.56 għal Seroquel 600 mg/kuljum.
English: Quetiapine does not produce dopamine D2-receptor supersensitivity after chronic administration.
Maltese: Wara li jingħata b'mod kroniku quetiapine ma jikkawżax supersensittività tarriċettur-D2 ta' dopamine.
English: Xeroquel LP
Maltese: Seroquel Prolong Xeroquel LP
English: 1 blister containing 6 x 25mg, 3 x 100mg and 1 x 200mg tablets
Maltese: Pakkett tal-Bidu ta' 4 ijiem 10 pilloli folja li fiha 6 x 25mg, 3 x 100mg u 1 x 200mg pilloli
English: The safety results showed a higher incidence of extrapyramidal symptoms reported in 16.8% of patients in the lithium add-on group and 6.6% in the placebo add-on group, the majority of which consisted of tremor, reported in 15.6% of the patients in the lithium add-on group and 4.9% in the placebo add-on group.
Maltese: Ir-riżultati dwar is-sigurtà urew inċidenza ogħla ta' sintomi ekstrapiramidali rrapportati f'16.8% talpazjenti fil-grupp li kellhom lithium miżjud u 6.6% fil-grupp li kellhom plaċebo miżjud, li lmaġġoranza tagħhom kienu jikkonsistu minn rogħda, irrapportata f'15.6% tal-pazjenti li kellhom lithium miżjud u 4.9% fil-grupp li kellhom plaċebo miżjud.
English: • add-on treatment of major depressive episodes in patients with Major Depressive Disorder (MDD) who have had sub-optimal response to antidepressant monotherapy (see Section 5.1).
Maltese: li kellhom rispons sub-ottimali għal monoterapija b'antidepressant (ara Sezzjoni 5.1).
English: The percentage of quetiapine treated patients who gained ≥7% of body weight ranged from 5.3% for the 50 mg daily dose to 15.5% for the 400 mg daily dose (with lower gain for the 600 and 800 mg daily doses), compared to 3.7% for placebo treated patients.
Maltese: 5% għad-doża ta' kuljum ta' 400 mg (b'żieda anqas għaddożi ta' kuljum ta' 600 u 800 mg), meta mqabbla ma' 3.7% għall-pazjenti li ngħataw kura bi plaċebo.
English: The incidence of somnolence was higher in the SEROQUEL XR with lithium add-on group (12.7%) compared to the SEROQUEL XR with the placebo add-on group (5.5%).
Maltese: L-inċidenza ta' ngħas kienet ogħla filgrupp ta' SEROQUEL XR li kellhom lithium miżjud (12.7%) meta mqabbla mal-grupp ta' SEROQUEL XR li kellhom plaċebo miżjud (5.5%).
English: Bowel obstruction.
Maltese: Disturbi vaskulari
English: Approximately 73% of a radiolabelled drug was excreted in the urine and 21% in the faeces with less than 5% of the total radioactivity representing unchanged drug-related material.
Maltese: Madwar 73% ta' mediċina radjutikkettata ġiet eliminata fl-awrina u 21% fl-ippurgar b'anqas minn 5% tar-radjuattività totali tirrapreżenta materjal mhux mibdul relatat mal-mediċina.
English: Seroquel XR contains lactose
Maltese: Seroquel XR fih lactose
English: Constipation, dyspepsia, vomiting
Maltese: Stitikezza, dispepsja, rimettar
English: NAME OF THE MEDICINAL PRODUCT Seroquel 25 mg, 100 mg and 200 mg tablets quetiapine
Maltese: Seroquel 25 mg, 100 mg u 200 mg pilloli quetiapine
English: 12 blisters of 10 tablets (150 mg and 300 mg tablets only)
Maltese: 12-il folja ta' 10 pilloli (150 mg u 300 mg pillola biss)
English: In a short-term placebo-controlled monotherapy trial in elderly patients with major depressive disorder, the aggregated incidence of extrapyramidal symptoms was 9.0% for Seroquel XR and 2.3% for placebo.
Maltese: Fi prova fuq żmien qasir b'monoterapija u kkontrollata bi plaċebo f'pazjenti anzjani b'disturb depressiv maġġuri, l-inċidenza aggregata ta' sintomi ekstrapiramidali kienet ta' 9.0% għal Seroquel XR u ta' 2.3% għal plaċebo.
English: (3) Asymptomatic elevations (shift from normal to > 3X ULN at any time) in serum transaminase (ALT, AST) or gamma-GT-levels have been observed in some patients administered quetiapine.
Maltese: 3. Żidiet asintomatiċi (bidla min-normal għal > 3X ULN fi kwalunkwe ħin) fit-transaminasi (ALT, AST) jew fillivelli tal-gamma-GT fis-serum kienu osservati f'xi pazjenti li ngħataw quetiapine.
English: In placebo-controlled clinical trials with children and adolescent patients, quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for schizophrenia, bipolar mania, and bipolar depression (see section 4.8).
Maltese: Fi provi kliniċi kkontrollati bi plaċebo b'pazjenti tfal u adolexxenti, quetiapine kien assoċjat ma' żieda fl-inċidenza ta' sintomi ekstrapiramidali (EPS) meta mqabbla ma' plaċebo f'pazjenti li kienu qed jirċievu kura għal skizofrenija, manija bipolari, u dipressjoni bipolari (ara sezzjoni 4.8).
English: 5 blisters of 10 tablets
Maltese: 5 folji ta' 10 pilloli
English: In all clinical trials (placebo-controlled, open-label, active comparator) in patients with a baseline neutrophil count ≥1.5 X 109/L, the incidence of at least one occurrence of a shift to neutrophil count <1.5 x 109/L was 2.9% and to <0.5 X 109/L was 0.21% in patients treated with quetiapine.
Maltese: Fil-provi kliniċi kollha (ikkontrollati bi plaċebo, b'tikketta miftuħa, b'komparatur attiv) f'pazjenti b'għadd tan-newtrofili fil-linja bażi ta' ≥1.5 X 109/L, l-inċidenza ta' mill-inqas okkorrenza waħda ta' bidla fl-għadd tan-newtrofili għal <1.5 x 109/L kienet ta' 2.9% u għal <0.5 X 109/L kienet ta' 0.21% f'pazjenti li ngħataw kura bi quetiapine .
English: Increases in triglycerides, LDL and total cholesterol, and decreases in HDL cholesterol have been observed in clinical trials with quetiapine (see section 4.8).
Maltese: Fi provi kliniċi bi quetiapine ġew osservati żidiet fit-trigliċeridi, l-LDL u l-kolesterol totali, u tnaqqis fil-kolesterol HDL (ara sezzjoni 4.8).
English: In short term, fixed dose (50mg/d to 800 mg/d), placebo-controlled studies (ranging from 3 to 8 weeks), the mean weight gain for quetiapine-treated patients ranged from 0.8 kg for the 50 mg daily dose to 1.4 kg for the 600 mg daily dose (with lower gain for the 800 mg daily dose), compared to 0.2 kg for the placebo treated patients.
Maltese: Fi studji fuq żmien qasir, b'doża fissa (50mg/d sa 800 mg/d), ikkontrollati bi plaċebo (bejn 3 sa 8 ġimgħat), iż-żieda medja fil-piż għal pazjenti li ngħataw kura bi quetiapine kienet tvarja minn 0.8 kg għad-doża ta' kuljum ta' 50 mg sa 1.4 kg għad-doża ta' kuljum ta' 600 mg (b'żieda anqas għad-doża ta' kuljum ta' 800 mg), meta mqabbla ma' 0.2 kg għall-pazjenti li ngħataw kura bi plaċebo.
English: • The active substance is quetiapine.
Maltese: • X'fih Seroquel • Is-sustanza attiva hija quetiapine.
English: For 3Day Starterpack pack size of 8 tablets is registered and for 4-Day Starterpack pack size of 10 tablets is registered.
Maltese: Għal Pakkett tal-Bidu ta' 3 ijiem, huwa rreġistrat daqs tal-pakkett ta' 8 pilloli u għal Pakkett tal-Bidu ta' 4 ijiem, huwa rreġistrat daqs ta' pakkett ta' 10 pilloli.
English: The 25 mg, 100 mg and 150 mg tablet also contain iron oxide yellow (E172) and the 25 mg contain iron oxide red (E172).
Maltese: Il-pilloli ta' 25 mg, 100 mg u 150 mg fihom ukoll iron oxide yellow (E172) u l-pilloli ta' 25 mg fihom iron oxide red (E172).
English: o For the treatment of moderate to severe manic episodes in bipolar disorder o For the treatment of major depressive episodes in bipolar disorder o For the prevention of recurrence of manic or depressed episodes in patients with bipolar disorder who previously responded to quetiapine treatment.
Maltese: o Għall-kura ta' episodji manijaċi moderati għal severi f'disturb bipolari o Għall-kura ta' episodji depressivi maġġuri f'disturb bipolari o Għall-prevenzjoni ta' rikorrenza ta' episodji manijaċi jew depressivi f'pazjenti b'disturb bipolari li qabel irrispondew għall-kura bi quetiapine.
English: In short-term, placebocontrolled bipolar depression trials the aggregated incidence of extrapyramidal symptoms was 8.9% for quetiapine compared to 3.8% for placebo.
Maltese: Fi provi fuq żmien qasir u kkontrollati bi plaċebo ta' dipressjoni bipolari l-inċidenza aggregata ta' sintomi ekstrapiramidali kienet ta' 8.9% għal quetiapine meta mqabbla ma' 3.8% għal plaċebo.
English: Dysarthria
Maltese: KUMMERĊJALI
English: Seroquel XR with food, drink and alcohol
Maltese: Seroquel XR ma' ikel, xorb u alkoħol
English: The 50 mg, 200 mg and 300 mg tablets also contain iron oxide yellow (E172) and the 50 mg tablets contain iron oxide red (E172).
Maltese: Il-pilloli ta' 50 mg, 200 mg u 300 mg fihom ukoll iron oxide yellow (E172) u l-pilloli ta' 50 mg fihom iron oxide red (E172).
English: Seroquel XR 50 mg prolonged-release tablets Seroquel XR 150 mg prolonged-release tablets Seroquel XR 200 mg prolonged-release tablets Seroquel XR 300 mg prolonged-release tablets Seroquel XR 400 mg prolonged-release tablets
Maltese: Seroquel XR 50 mg pilloli li jerħu l-mediċina bil-mod Seroquel XR 150 mg pilloli li jerħu l-mediċina bil-mod
English: In four placebo-controlled clinical trials, evaluating doses of Seroquel up to 800 mg/day for the treatment of moderate to severe manic episodes, two each in monotherapy and as combination therapy to lithium or divalproex, there were no differences between the Seroquel and placebo treatment groups in the incidence of EPS or concomitant use of anticholinergics.
Maltese: F'erba' provi kliniċi kkontrollati bi plaċebo, li evalwaw id-dożi ta' Seroquel sa 800 mg/kuljum għallkura ta' episodji manijaċi moderati sa serji, tnejn kull wieħed f'monoterapija u bħala terapija kkombinata għal lithium jew divalproex, ma kienx hemm differenzi bejn il-gruppi ta' kura ta' Seroquel u plaċebo fl-inċidenza ta' EPS jew l-użu konkomitanti ta' antikolinerġiċi.
English: The rates of weight gain ≥ 7% of baseline body weight in the active arm vs. placebo were 17% vs. 2.5% in the schizophrenia and bipolar mania trials, and 12.5% vs. 6% in the bipolar depression trial.
Maltese: skizofrenija u ta' manija bipolari, u ta' 12.5% kontra 6% fil-prova ta' dipressjoni bipolari.
English: It is important that any change in the inducer is gradual, and if required, replaced with a non-inducer (e.g. sodium valproate) (see section 4.4).
Maltese: Huwa importanti li kwalunkwe bidla fl-induttur tkun gradwali, u jekk meħtieġ, jiġi sostitwit b'wieħed li mhux induttur (eż. sodium valproate) (ara sezzjoni 4.4).
English: Seizures:
Maltese: Aċċessjonijiet:
English: This is further supported by the data from a positron emission tomography (PET) study, which identified that for quetiapine, 5HT2- and D2-receptor occupancy are maintained for up to 12 hours.
Maltese: Dan huwa appoġġjat iktar mill-informazzjoni minn studju tat-tomografija tal-emissjoni ta' positron (PET), li identifika li għal quetiapine, l-okkupanza tar-riċetturi 5HT2- u D2tinżamm sa 12-il siegħa.
English: 2 blisters of 10 tablets
Maltese: 2 folji ta' 10 pilloli
English: Seroquel 100 mg contains 100 mg quetiapine (as quetiapine fumarate) Excipient : 20 mg lactose (anhydrous) per tablet
Maltese: Eċċipjent : 18 mg ta' lattosju (anidru) f'kull pillola Seroquel 100 mg fih 100 mg quetiapine (bħala quetiapine fumarate) Eċċipjenti : 20 mg ta' lattosju (anhydrous) f'kull pillola
English: A placebo-controlled trial evaluating fixed doses of quetiapine across the range of 75 to 750 mg/day showed no evidence of an increase in EPS or the use of concomitant anticholinergics.
Maltese: Prova kkontrollata bi plaċebo li tevalwa d-dożi fissi ta' quetiapine madwar il-firxa ta' 75 sa 750 mg/kuljum ma wriet ebda evidenza ta'
English: INFORMATION IN BRAILLE Seroquel XR 200 mg
Maltese: INFORMAZZJONI BIL-BRAILLE Seroquel XR 200 mg
English: Seroquel XR achieves peak quetiapine and norquetiapine plasma concentrations at approximately 6 hours after administration (Tmax).
Maltese: Seroquel XR jilħaq l-ogħla konċentrazzjonijiet ta' quetiapine u norquetiapine fil-plasma madwar 6 sigħat wara li jingħata (Tmax).
English: Less than 1% of patients had an increase to a prolactin level >100 ug/L.
Maltese: Anqas minn 1% tal-pazjenti kellhom żieda fil-livell tal-prolactin >100 ug/L.
English: Seroquel 4-Day Starterpack contains 6 tablets Seroquel 25 mg, 3 tablets Seroquel 100 mg and 1 tablet Seroquel 200 mg
Maltese: Seroquel Pakkett tal-Bidu ta' 4 ijiem fih 6 pilloli Seroquel 25 mg, 3 pilloli Seroquel 100 mg u pillola waħda Seroquel 200 mg Għal-lista kompluta ta' eċċipjenti, ara sezzjoni 6.1.
English: • Bowel obstruction.
Maltese: • Disturb mestrwali.
English: The daily dose at the start of therapy is 50 mg on Day 1 and 2, and 150 mg on Day 3 and 4.
Maltese: Id-doża ta' kuljum fil-bidu tat-terapija hija ta' 50 mg f'Jum 1 u 2, u ta' 150 mg f'Jum 3 u 4.
English: The mean plasma clearance of quetiapine was reduced by approximately 25% in subjects with severe renal impairment (creatinine clearance less than 30 ml/min/1.73 m2), but the individual clearance values are within the range for normal subjects.
Maltese: It-tneħħija medja ta' quetiapine mill-plasma tnaqqset b'madwar 25% f'individwi b'indeboliment sever tal-kliewi (tneħħija tal-kreatinina ta' anqas minn 30 ml/min/1.73 m2), iżda l-valuri individwali ta' tneħħija huma fil-medda ta' individwi normali.
English: This belongs to a group of medicines called antipsychotics.
Maltese: Din tagħmel parti minn grupp ta' mediċini msejħa antipsikotiċi.
English: Musculoskeletal and connective tissue disorders
Maltese: Disturbi muskolu skeletriċi u tat tessuti konnettivi
English: 6 x 25 mg film-coated tablets 3 x 100 mg film-coated tablets 1 x 200 mg film-coated tablets
Maltese: 6 x 25 mg pilloli miksijin b'rita 3 x 100 mg pilloli miksijin b'rita 1 x 200 mg pillola miksija b'rita
English: In clinical trials for treatment of patients with bipolar depression and major depressive disorder, onset was usually within the first 3 days of treatment and was predominantly of mild to moderate intensity.
Maltese: Fi provi kliniċi għall-kura ta' pazjenti b'dipressjoni bipolari u b'disturb depressiv maġġuri, ġeneralment dan beda fi żmien l-ewwel 3 ijiem tal-kura u predominantement kien ta' intensità ħafifa għal moderata.
English: 9 blisters of 10 tablets
Maltese: 9 folji ta' 10 pilloli
English: Seroquel 25 mg, 100 mg, 150 mg, 200 mg, 300 mg film-coated tablets Seroquel 3-Day Starterpack (Combined pack) Seroquel 4-Day Starterpack quetiapine
Maltese: Seroquel 25 mg, 100 mg, 150 mg, 200 mg, 300 mgpilloli Seroquel Pakkett tal-Bidu ta' 3 ijiem (Pakkett ikkombinat) Seroquel Pakkett tal-Bidu ta' 4 ijiem quetiapine Aqra sew dan il-fuljett kollu qabel tibda tieħu din il-mediċina peress li fih informazzjoni importanti għalik.
English: INFORMATION IN BRAILLE Seroquel XR 150 mg
Maltese: INFORMAZZJONI BIL-BRAILLE Seroquel XR 150 mg
English: 1 blister containing 6 x 25 mg and 2 x 100 mg tablets
Maltese: 8 pilloli folja li fiha 6 x 25 mg u 2 x 100 mg pilloli
English: NAME OF THE MEDICINAL PRODUCT Seroquel 25 mg and 100 mg tablets quetiapine
Maltese: Seroquel 25 mg u 100 mg pilloli quetiapine
English: Asymptomatic elevations (shift from normal to > 3X ULN at any time) in serum transaminase (ALT, AST) or gamma-GT-levels have been observed in some patients administered quetiapine.
Maltese: Żidiet asintomatiċi (bidla min-normal għal > 3X ULN fi kwalunkwe ħin) fit-transaminasi (ALT, AST) jew fil livelli tal-gamma-GT fis-serum kienu osservati f'xi pazjenti li ngħataw quetiapine.
English: • If you are allergic (hypersensitive) to quetiapine or any of the other ingredients of Seroquel XR (see section 6: Further information)
Maltese: • Jekk inti allerġiku (tbati minn sensittività eċċessiva) għal quetiapine jew għal xi sustanza oħra ta' Seroquel XR (ara sezzjoni 6: Informazzjoni oħra)
English: The long-term efficacy of Seroquel IR in prevention of schizophrenic relapses has not been verified in blinded clinical trials.
Maltese: L-effikaċja fit-tul ta' Seroquel IR filprevenzjoni ta' rikaduti skiżofreniċi ma ġietx ivverifikata fi provi kliniċi blinded.
English: 1 blister of 10 tablets
Maltese: Folja 1 ta' 10 pilloli
English: On the basis of this, concomitant use of quetiapine with CYP3A4 inhibitors is contraindicated.
Maltese: CYP3A4 huwa kontraindikat.
English: Hyperprolactina emia decreases in total T4 decreases in free T4 decreases in total T3 increases in TSH
Maltese: Iperprolaktinimj a15, tnaqqis fitT4 totali tnaqqis fit-T4
English: Seroquel 200 mg contains 200 mg quetiapine (as quetiapine fumarate) Excipient : 39 mg lactose (anhydrous) per tablet
Maltese: Seroquel 200 mg fih 200 mg ta' quetiapine (bħala quetiapine fumarate)
English: The pharmacokinetics of sodium valproate and quetiapine were not altered to a clinically relevant extent when co-administered.
Maltese: Il-farmakokinetika ta' sodium valproate u quetiapine ma kinitx mibdula b'mod klinikament rilevanti meta ngħataw flimkien.
English: In all short-term placebo-controlled monotherapy trials in patients with a baseline neutrophil count ≥1.5 X 109/L, the incidence of at least one occurrence of a shift to neutrophil count <1.5 X 109/L, was 1.9% in patients treated with quetiapine compared to 1.5% in placebo-treated patients.
Maltese: Fil-provi kollha fuq żmien qasir b'monoterapija u kkontrollati bi plaċebo f'pazjenti b'għadd tan newtrofili fil-linja bażi ta' ≥1.5 X 109/L, l-inċidenza ta' mill-inqas okkorrenza waħda ta' bidla fl għadd tan-newtrofili ta' <1.5 X 109/L, kienet ta' 1.9% f'pazjenti li ngħataw kura bi quetiapine meta mqabbla ma' 1.5% f'pazjenti li ngħataw kura bi plaċebo.
English: As quetiapine is extensively metabolised by the liver, elevated plasma levels are expected in the population with hepatic impairment.
Maltese: Peress li quetiapine jiġi metabolizzat b'mod estensiv mill fwied, huwa mistenni li fil-popolazzjoni b'indeboliment tal-fwied il-livelli fil-plasma ikunu ogħla.
English: Based on >7% increase in body weight from baseline.
Maltese: Abbażi ta' żieda ta' >7% fil-piż tal-ġisem mil-linja bażi.
English: Inappropriate antidiuretic hormone secretion
Maltese: Sekrezzjoni mhux approprjata tal-ormon antidijuretiku
English: Blisters:
Maltese: XR:
English: • Swelling of breasts and unexpected production of breast milk (galactorrhoea).
Maltese: • Nefħa fis-sider u l-produzzjoni mhux mistennija ta' ħalib tas-sider (galaktorreja).
English: Leucopenia 1, 28,
Maltese: Iponatremja Dijabete Mellitus 1, 5
English: (30) In some patients, a worsening of more than one of the metabolic factors of weight, blood glucose and lipids was observed in clinical studies (See Section 4.4).
Maltese: F'xi pazjenti, aggravar ta' aktar minn fattur metaboliku wieħed ta' piż, glukosju fid-demm u lipidi kien osservat fi studji tekniċi (Ara Sezzjoni 4.4).
English: Seroquel United Kingdom Seroquel
Maltese: Mediċini oħra u Seroquel
English: 6 blisters of 10 tablets
Maltese: 6 folji ta' 10 pilloli
English: • Do not drink grapefruit juice while you are taking Seroquel.
Maltese: • Tixrobx meraq tal-grejpfrut waqt li tkun qed tieħu Seroquel.
English: INFORMATION IN BRAILLE Seroquel XR 400 mg
Maltese: INFORMAZZJONI BIL-BRAILLE Seroquel XR 400 mg
English: Elevations in blood creatine phosphokinase
Maltese: Żidiet fil-creatine phosphokinase fid-demm
English: • Barbiturates (for difficulty sleeping).
Maltese: • Barbiturati (għal problemi tal-irqad).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Seroquel 25 mg contains 25 mg quetiapine (as quetiapine fumarate) Excipient : 18 mg lactose (anhydrous) per tablet
Maltese: U KWANTITATTIVA Seroquel 25 mg fih 25 mg ta' quetiapine (bħala quetiapine fumarate)
English: In an interaction study in healthy volunteers, concomitant administration of quetiapine (dosage of 25 mg) with ketoconazole, a CYP3A4 inhibitor, caused a 5- to 8
Maltese: Fi studju ta' interazzjoni fuq voluntiera b'saħħithom, l-għoti ta' quetiapine (doża ta' 25 mg) flimkien ma' ketoconazole, inibitur ta' CYP3A4, ikkawża żieda ta'
English: Paediatric Population
Maltese: Popolazzjoni Pedjatrika
English: INFORMATION IN BRAILLE Seroquel XR 50 mg
Maltese: INFORMAZZJONI BIL-BRAILLE Seroquel XR 50 mg
English: 24, Hypothyroidi sm
Maltese: ħieles 24, Ipotirojdiżmu