FrancophonIA/ELRC3.0 huggingface dataset:
English: Keep the product protected from light.
Slovenian: Zdravilo shranjujte zaščiteno pred svetlobo.
English: The increase from baseline in lumbar spine and femoral neck BMD was 6.8% and 2.2%, respectively in patients treated with Preotact.
Slovenian: Pri bolnicah, zdravljenih z zdravilom Preotact, se je BMD ledvenega predela hrbtenice povečal za 6,8%, BMD femoralnega vratu pa za 2,2% nad izhodiščnimi vrednostmi.
English: 4.9 Overdose
Slovenian: 4.9 Preveliko odmerjanje Znaki in simptomi
English: After reconstitution, each dose of 71.4 microlitre contains 100 micrograms parathyroid hormone produced in Escherichia coli by recombinant DNA technology For a full list of excipients, see section 6.1.
Slovenian: Po rekonstituciji en odmerek z 71,4 mikrolitri vsebuje 100 mikrogramov obščitničnega hormona, ki je pridobljen v Escherichia coli s tehnologijo rekombinantne DNA.
English: • Do not store the pre-filled pen with the needle on.
Slovenian: • Ne shranjujte napolnjenega injekcijskega peresnika z nataknjeno iglo.
English: Significant increases in hip BMD (total, femoral neck, trochanter) were observed at study endpoint; 1.0, 1.8 and 1.0%, respectively, for Preotact versus -1.1,0.7 and -0.6% for placebo (p<0.001).
Slovenian: Pri merjenju ciljev študije so opazili statistično značilno povečanje BMD kolka, in sicer v skupini bolnic, ki so prejemale zdravilo Preotact: skupno 1,0%, v femoralnem vratu 1,8%, v trohantru 1,0%, v primerjavi s skupino bolnic, ki so prejemale placebo: skupno -1,1%, v femoralnem vratu -0,7%, v trohantru -0,6% (p<0,001).
English: No dose adjustment is needed for patients with mild or moderate hepatic impairment (total score of 7 to 9 on the Child-Pugh scale).
Slovenian: Pri bolnicah z blago do zmerno okvaro jeter (skupno število točk po lestvici Child-Pugh od 7 do 9) ni treba prilagajati odmerka.
English: Preotact 100 micrograms powder and solvent for solution for injection in a pre-filled pen Parathyroid hormone
Slovenian: Preotact 100 mikrogramov prašek in vehikel za raztopino za injiciranje v napolnjenem injekcijskem peresniku obščitnični hormon
English: Do not use Preotact • if you are allergic to parathyroid hormone or any of the other ingredients of this medicine (listed
Slovenian: • če ste alergični na obščitnični hormon ali katero koli sestavino tega zdravila (navedeno v poglavju 6);
English: Elevated serum calcium was observed during Preotact treatment.
Slovenian: Med zdravljenjem z zdravilom Preotact so opazili zvišane serumske ravni kalcija.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each pre-filled pen contains 1.61 mg parathyroid hormone corresponding to 14 doses.
Slovenian: KAKOVOSTNA IN KOLIČINSKA SESTAVA En napolnjen injekcijski peresnik vsebuje 1,61 mg obščitničnega hormona, kar ustreza 14 odmerkom.
English: The MAH commits to performing the studies and additional pharmacovigilance activities detailed in the Pharmacovigilance Plan, as agreed in version 03 of the Risk Management Plan (RMP) presented in Module 1.8.2. of the Marketing Authorisation and any subsequent updates of the RMP agreed by the CHMP.
Slovenian: načrta za obvladovanje tveganja (RMP), predloženem v modulu 1.8.2 vloge za pridobitev dovoljenja za promet z zdravilom, in vseh nadaljnjih posodobitvah RMP v soglasju z Odborom za zdravila za uporabo v humani medicini (CHMP).
English: Volumetric trabecular BMD at the lumbar spine increased by 26, 13, and 11% (Preotact, Preotact and alendronate and alendronate, respectively) over baseline at 12 months.
Slovenian: Volumetrični trabekularni BMD v ledvenem predelu hrbtenice se je od izhodiščnih vrednosti v 12 mesecih povečal za 26% v skupini, ki je prejemala zdravilo Preotact, za 13% v skupini, ki je prejemala zdravilo Preotact in alendronat, in za 11% v skupini, ki je prejemala alendronat.
English: • You can store the mixed pre-filled pen for up to 7 days at room temperature, between 2-25°C.
Slovenian: • Napolnjen injekcijski peresnik z zmešanim zdravilom lahko shranjujete do 7 dni pri sobni temperaturi od 2 °C- 25 °C.
English: Pre-filled pen(after reconstitution): Store in a refrigerator (2-8°C).
Slovenian: Napolnjen injekcijski peresnik (po pripravi): Shranjujte v hladilniku (2 °C - 8 °C).
English: Preotact is a powder and solvent for solution for injection in a pre-filled pen.
Slovenian: Zdravilo Preotact je prašek in vehikel za raztopino za injiciranje v napolnjenem injekcijskem peresniku.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Pre-filled pen
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH
English: • Ensure that you have a needle on the pre-filled pen (see pictures 3 and 4).
Slovenian: (glejte sliki 3 in 4).
English: • constipation, diarrhoea,
Slovenian: • zaprtost, driska,
English: Reconstituted solution: Store in a refrigerator (2-8°C).
Slovenian: Pripravljena raztopina: Shranjujte v hladilniku (2 °C - 8 °C).
English: Every day you have to check that the medicine is clear, add a new needle, take the injection in your abdomen and then throw away the needle before storing your pre-filled pen in the refrigerator (2-8°C).
Slovenian: Vsak dan morate preveriti, če je zdravilo bistro, dodati novo iglo, se zbosti v trebuh in nato zavreči iglo,
English: • increased level of calcium in the blood,
Slovenian: • zvišana raven kalcija v krvi,
English: The pre-filled pen after mixing:
Slovenian: Napolnjen injekcijski peresnik po mešanju:
English: Increases in BMD at the total hip were 0.3, 1.9, and 3.0% for the 3 groups, respectively.
Slovenian: Povečki BMD celotnega kolka so bili 1,9% v prvi omenjeni skupini,
English: Pinch a skin fold in the abdomen and take the injection in a 90° degree angle as you have been instructed by your doctor or nurse.
Slovenian: S prsti stisnite kožno gubo na trebuhu in naredite vbod z injekcijsko iglo pod kotom 90°,
English: Langebjerg 1, 4000 Roskilde
Slovenian: Nycomed Danmark ApS Langebjerg 1, 4000 Roskilde Danska
English: • stomach upset, vomiting,
Slovenian: • razdražen želodec, bruhanje, • utrujenost.
English: • sodium chloride,
Slovenian: • natrijev klorid
English: Parathyroid hormone is efficiently removed from the blood by a receptor-mediated process in the liver and is broken down into smaller peptide fragments.
Slovenian: Obščitnični hormon se v jetrih učinkovito odstranjuje iz krvi s procesi, ki jih posredujejo receptorji,
English: Preotact is available in packs of 2 pre-filled pens.
Slovenian: Zdravilo je na voljo v pakiranju z 2 napolnjenima injekcijskima peresnikoma.
English: Once the cartridge is reconstituted it can be stored below 25°C for up to 7 days during the 28 day use time.
Slovenian: Ko je raztopina v vložku pripravljena, lahko zdravilo shranjujete pri temperaturi do 25 °C do 7 dni v 28-dnevnem obdobju uporabnosti.
English: Ask your doctor or pharmacist for advice before taking any medicine Do not use Preotact if you are pregnant or breast-feeding.
Slovenian: Če ste noseči ali če dojite, ne uporabljajte zdravila Preotact.
English: There are no data available from the use of parathyroid hormone in women of childbearing potential, during pregnancy and breast feeding.
Slovenian: 4.6 Plodnost, nosečnost in dojenje Ni podatkov o uporabi obščitničnega hormona pri ženskah v rodni dobi, med nosečnostjo in med dojenjem.
English: Each cartridge inside the prefilled pen contains 1.61 mg parathyroid hormone and 1.13 ml solvent (14 doses).
Slovenian: En vložek znotraj napolnjenega injekcijskega peresnika vsebuje po 1,61 mg obščitničnega hormona in 1,13 ml vehikla (14 odmerkov).
English: Injection site irritation
Slovenian: Eritem na mestu injiciranja Utrujenost
English: Diarrhoea
Slovenian: Anoreksija
English: Clinical efficacy
Slovenian: KLINIČNI PODATKI
English: The following adverse reaction (ADR) data are based on two placebo-controlled studies involving 2,642 postmenopausal osteoporotic women of whom 1,341 received parathyroid hormone.
Slovenian: študiji so vključili 2642 pomenopavznih žensk z osteoporozo, od katerih jih je 1341 prejemalo obščitnični hormon.
English: There is no data available in patients with severe hepatic impairment.
Slovenian: O odmerjanju pri bolnicah s hudo okvaro jeter ni podatkov.
English: • increased level of calcium in the urine,
Slovenian: • zvišana raven kalcija v urinu,
English: • suffer from kidney stones;
Slovenian: • imate ledvične kamne,
English: Measuring of the calcium levels in the blood and/or urine Your doctor will check your response to the treatment at regular intervals.
Slovenian: Vaš zdravnik bo v rednih časovnih presledkih preverjal odziv na zdravljenje.
English: Preotact is available in a pack with 2 pre-filled pens.
Slovenian: Zdravilo je na voljo v pakiranju, ki vsebuje 2 napolnjena injekcijska peresnika.
English: The medicinal product is supplied in a pre-filled pen containing a dual-chamber cartridge.
Slovenian: Zdravilo je na voljo v napolnjenem injekcijskem peresniku, ki vsebuje en vložek z dvema komoroma.
English: Preotact should be used with caution in patients with active or previous urolithiasis.
Slovenian: Zdravilo Preotact moramo pri bolnicah z aktivno urolitiazo ali anamnezo te bolezni uporabljati previdno.
English: Dysgeusia
Slovenian: Dizgevzija Parozmija
English: Each pre-filled pen contains 1.61 mg parathyroid hormone corresponding to 14 doses.
Slovenian: En napolnjen injekcijski peresnik vsebuje 1,61 mg obščitničnega hormona, kar ustreza 14 odmerkom.
English: Injection site erythema
Slovenian: Draženje na mestu injiciranja
English: LIST OF EXCIPIENTS
Slovenian: Števec odmerkov
English: Pull the cap straight off from the front end of the pre-filled pen.
Slovenian: Povlecite in odstranite pokrov s sprednjega dela napolnjenega injekcijskega peresnika.
English: The volume of distribution at steady-state following intravenous administration is approximately 5.4 l. Interindividual variability in the volume of distribution of parathyroid hormone is about 40%.
Slovenian: Interindividualna variabilnost volumna porazdelitve obščitničnega hormona je približno 40%.
English: Parosmia
Slovenian: SERIJE
English: • increased level of uric acid in the blood,
Slovenian: • zvišana raven sečne kisline v krvi,
English: Wash your hands with soap and water before you handle the pre-filled pen.
Slovenian: Pred rokovanjem z napolnjenim injekcijskim peresnikom si umijte roke z vodo in milom.
English: In the pivotal study, Preotact increased BMD in the lumbar spine after 18 months treatment by 6.5% compared with -0.3% for placebo (p<0.001).
Slovenian: 6,5% v primerjavi z -0,3% pri bolnicah, ki so prejemale placebo (p<0,001).
English: • You can store the mixed pre-filled pen for up to 7 days outside the refrigerator (below 25°C)
Slovenian: • Pripravljen napolnjen injekcijski peresnik lahko shranjujete izven hladilnika (pri temperaturi do 25 °C) največ do 7 dni v 28-dnevnem obdobju uporabnosti.
English: Keep the pre-filled pen in the outer carton in order to protect from light.
Slovenian: Za zagotovitev zaščite pred svetlobo shranjujte napolnjen injekcijski peresnik v zunanji škatli.
English: What you need to know before you use Preotact
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Preotact Ne uporabljajte zdravila Preotact:
English: Hepatic impairment
Slovenian: Pogosti Glavobol Omotica
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 1.61 mg parathyroid hormone and 1.13 ml solvent (14 doses)
Slovenian: 1,61 mg obščitničnega hormona in 1,13 ml vehikla (14 odmerkov)
English: Elderly
Slovenian: Astenija
English: Asthenia
Slovenian: Zdravilo
English: Vomiting
Slovenian: Vehikel
English: Posology The recommended dose is 100 micrograms of parathyroid hormone administered once-daily
Slovenian: Priporočeni odmerek je 100 µg obščitničnega hormona enkrat dnevno.
English: METHOD AND ROUTE(S) OF ADMINISTRATION Do not shake the reconstituted solution Read the package leaflet before use Subcutaneous use
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA Pripravljene raztopine ne stresajte.
English: Talk to your doctor or pharmacist before using Preotact if you:
Slovenian: Pred začetkom uporabe zdravila Preotact se posvetujte s svojim zdravnikom ali s farmacevtom, če
English: Check with your doctor or pharmacist if you are not sure.
Slovenian: Posvetujte se z zdravnikom ali s farmacevtom, preden vzamete katerokoli zdravilo.
English: 2 pre-filled pens per pack.
Slovenian: škatla z 2 napolnjenima injekcijskima peresnikoma
English: Name and address of the manufacturer responsible for batch release Nycomed Danmark ApS
Slovenian: Ime in naslov izdelovalca, odgovornega za sproščanje serije
English: • abdominal pain,
Slovenian: • bolečine v trebuhu,
English: • with severe hepatic impairment
Slovenian: • s hudimi okvarami ledvic • s hudimi okvarami jeter
English: Please see how to use the pen in the Instructions for use manual.
Slovenian: Navodilo za uporabo peresnika si, prosimo, oglejte v priloženem navodilu.
English: Lot
Slovenian: Spol
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each pre-filled pen contains 1.61 mg parathyroid hormone corresponding to 14 doses.
Slovenian: NAVEDBA ENE ALI VEČ ZDRAVILNIH UČINKOVIN En napolnjen injekcijski peresnik vsebuje 1,61 mg obščitničnega hormona, kar ustreza 14 odmerkom.
English: Gastrointestinal disorders Very common
Slovenian: Zelo pogosti Hiperkalciurija
English: Each pre-filled pen contains 1.61 mg of parathyroid hormone as powder and 1.13 ml of solvent.
Slovenian: En napolnjen injekcijski peresnik vsebuje 1,61 mg obščitničničnega hormona v obliki praška in
English: • Take the daily injection • Store the pre-filled pen
Slovenian: • Vzamete dnevno injekcijo
English: The steps you have to go through with a new pre-filled pen:
Slovenian: Z novim napolnjenim injekcijskim peresnikom morate opraviti naslednje korake:
English: Antibodies to parathyroid hormone
Slovenian: Obščitnični hormon
English: Blood alkaline phosphatase increased Anorexia
Slovenian: Zvišana vrednost alkalne fosfataze v krvi
English: NAME OF THE MEDICINAL PRODUCT Preotact 100 micrograms powder and solvent for solution for injection in a pre-filled pen.
Slovenian: Preotact 100 mikrogramov prašek in vehikel za raztopino za injiciranje v napolnjenem injekcijskem peresniku
English: What Preotact contains -The active substance is parathyroid hormone.
Slovenian: -Zdravilna učinkovina je obščitnični hormon.
English: This overview was last updated in 09-2014.
Slovenian: Pregled je bil nazadnje posodobljen 09-2014.
English: Further information on Eliquis can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Slovenian: Nadaljnje informacije za zdravilo Eliquis so na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: It is available as tablets (2.5 mg, 5 mg).
Slovenian: Na voljo je v obliki tablet (2,5 in 5 mg).
English: Thrombin is central to the process of blood clotting.
Slovenian: Trombin ima osrednjo vlogo v postopku strjevanja krvi.
English: The European Medicines Agency decided that Eliquis' benefits are greater than its risks and it can be authorised for use in the EU.
Slovenian: Evropska agencija za zdravila je zaključila, da so koristi zdravila Eliquis večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
English: Eliquis received a marketing authorisation valid throughout the EU on 18 May 2011.
Slovenian: Za zdravilo Eliquis je bilo 18. maja 2011 izdano dovoljenje za promet, veljavno po vsej EU.
English: What measures are being taken to ensure the safe and effective use of Eliquis?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Eliquis?
English: Eliquis (apixaban)
Slovenian: Eliquis (apiksaban)
English: As for all medicines, data on the use of Eliquis are continuously monitored.
Slovenian: Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila Eliquis stalno spremljajo.
English: Other information about Eliquis
Slovenian: Druge informacije o zdravilu Eliquis
English: For patients who have had a hip or knee replacement, treatment with Eliquis should be started 12 to 24 hours after the operation.
Slovenian: Pri bolnikih po kirurški zamenjavi kolka ali kolena je treba zdravljenje z zdravilom Eliquis začeti od 12 do 24 ur po operaciji.
English: For more information about using Eliquis, see the package leaflet or contact your doctor or pharmacist.
Slovenian: Za več informacij glede uporabe zdravila Eliquis glejte navodilo za uporabo ali se posvetujte z zdravnikom ali farmacevtom.
English: The recommended dose is one 2.5 mg tablet taken by mouth twice a day, usually for over one month (32 to 38 days) after a hip replacement or for 10 to 14 days after a knee replacement.
Slovenian: Priporočeni odmerek je ena 2,5-miligramska tableta; jemlje se dvakrat na dan peroralno, običajno več kot en mesec (od 32 do 38 dni) po kirurški zamenjavi kolka oziroma od 10 do 14 dni po kirurški zamenjavi kolena.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Eliquis have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Eliquis upoštevati zdravstveni delavci in bolniki, so vključeni v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: What benefits of Eliquis have been shown in studies?
Slovenian: Kakšne koristi zdravila Eliquis so se pokazale v študijah?
English: It is used in patients who have one or more risk factors, such as having had a previous stroke, having high blood pressure, diabetes, heart failure or being 75 years old or over.
Slovenian: Uporablja se pri bolnikih z enim ali več dejavniki tveganja, kot so možganska kap v preteklosti, visok krvni tlak, sladkorna bolezen, srčno popuščanje ali starost 75 let ali več.
English: The most frequent side effects with Eliquis (seen in between 1 and 10 patients in 100) are anaemia (low red blood cell counts), haemorrhage (bleeding), haematoma (a collection of blood under the skin), contusion (bruising), nausea (feeling sick), low blood pressure (hypotension), epistaxis (nose bleeds), haematuria (blood in urine), low blood platelet counts (thrombocytopenia), blood tests showing alanine aminotransferase and gamma-glutamyltransferase increase and skin rash.
Slovenian: Najpogostejši neželeni učinki zdravila (opaženi pri 1 do 10 od 100 bolnikov) so anemija (nizko število rdečih krvnih celic), krvavitve, hematom (izliv krvi pod kožo), podplutbe, navzea (siljenje na bruhanje), nizek krvni tlak (hipotenzija), epistaksa (krvavitve iz nosu), hematurija (kri v urinu), nizko število trombocitov (trombocitopenija), krvni testi, ki kažejo zvišane ravni alanin-aminotransferaze in gama-glutamiltransferaze, ter kožni izpuščaji.
English: Why is Eliquis authorised in the EU?
Slovenian: Zakaj je bilo zdravilo Eliquis odobreno v EU?
English: The company that markets Eliquis will provide educational material for healthcare professionals expected to prescribe Eliquis that addresses the risk of bleeding during treatment.
Slovenian: Podjetje, ki trži zdravilo Eliquis, bo priskrbelo izobraževalno gradivo za zdravstvene delavce, ki bodo predvidoma predpisovali zdravilo Eliquis, in v njem opisalo tveganja za krvavitve med zdravljenjem.
English: An overview of Eliquis and why it is authorised in the EU
Slovenian: Pregled zdravila Eliquis in zakaj je odobreno v EU
English: Side effects reported with Eliquis are carefully evaluated and any necessary action taken to protect patients.
Slovenian: Neželeni učinki, o katerih so poročali pri zdravilu Eliquis, se skrbno ovrednotijo in po potrebi sprejmejo ukrepi za zaščito bolnikov.
English: Similarly, patients with atrial fibrillation are at high risk of clots forming in the heart, which can reach the brain where they can cause a stroke.
Slovenian: Podobno pri bolnikih z atrijsko fibrilacijo obstaja veliko tveganje za nastanek strdkov v srcu; ti strdki lahko pridejo v možgane in povzročijo možgansko kap.
English: In both studies, Eliquis was compared with enoxaparin (another medicine used to prevent blood clots).
Slovenian: V obeh študijah so zdravilo Eliquis primerjali z enoksaparinom (drugim zdravilom za preprečevanje krvnih strdkov).
English: Some of these side effects are not seen with all the uses of Eliquis.
Slovenian: Nekateri od teh neželenih učinkov se ne pojavijo pri vseh načinih uporabe zdravila Eliquis.
English: The medicine must also not be used in patients with conditions putting them at risk of major bleeding, such as an ulcer in the gut, or in patients being treated with other anticoagulant medicines except in specific circumstances (see summary of product characteristics).
Slovenian: Zdravilo se prav tako ne sme uporabljati pri bolnikih z boleznimi, zaradi katerih pri njih obstaja tveganje za večje krvavitve, kot so razjede v črevesju, ali bolnikih, ki prejemajo druga antikoagulacijska zdravila, razen v posebnih okoliščinah (glejte povzetek glavnih značilnosti zdravila).
English: What is Eliquis and what is it used for?
Slovenian: Kaj je zdravilo Eliquis in za kaj se uporablja?
English: Eliquis must not be used in patients who are actively bleeding, or who have liver disease which leads to problems with blood clotting and an increased risk of bleeding.
Slovenian: Zdravilo Eliquis se ne sme uporabljati pri bolnikih z aktivno krvavitvijo ali boleznijo jeter, ki povzroča težave s strjevanjem krvi in večje tveganje za krvavitve.
English: What are the risks associated with Eliquis?
Slovenian: Kakšna tveganja so povezana z zdravilom Eliquis?
English: Eliquis was effective at preventing blood clots in the veins following a hip or knee replacement in two main studies involving a total of 8,464 patients.
Slovenian: Zdravilo Eliquis je bilo učinkovito pri preprečevanju krvnih strdkov v venah po kirurški zamenjavi kolka ali kolena v dveh glavnih študijah s skupno 8 464 bolniki.
English: It is also used in adults to treat deep vein thrombosis (blood clot in a deep vein, usually in the leg) and pulmonary embolism (clot in a blood vessel supplying the lungs), and to prevent their reoccurrence.
Slovenian: Uporablja se tudi pri odraslih za zdravljenje globoke venske tromboze (krvnega strdka v globoki veni, običajno v nogi) in pljučne embolije (strdka v krvni žili, ki oskrbuje pljuča) ter za preprečevanje njune ponovne pojavitve.
English: For the treatment of deep vein thrombosis and pulmonary embolism, the recommended dose is 10 mg twice a day for the first week, followed by 5 mg twice a day for at least 3 months.
Slovenian: Za zdravljenje globoke venske tromboze in pljučne embolije je priporočeni odmerek 10 mg dvakrat na dan prvi teden, nato pa 5 mg dvakrat na dan vsaj tri mesece.
English: Eliquis was also shown to be effective in preventing strokes and arterial blood clots in patients with atrial fibrillation in two main studies: the first (in 18,201 patients) compared Eliquis with another medicine, warfarin, while the second (in 5,598 patients) compared Eliquis with aspirin.
Slovenian: Poleg tega se je v dveh glavnih študijah zdravilo Eliquis izkazalo za učinkovito pri preprečevanju možganskih kapi in krvnih strdkov v arterijah pri bolnikih z atrijsko fibrilacijo: v prvi (z 18 201 bolnikom) so zdravilo Eliquis primerjali z drugim zdravilom, varfarinom, v drugi (s 5 598 bolniki) pa so zdravilo Eliquis primerjali z acetilsalicilno kislino (aspirinom).
English: In patients undergoing a knee replacement, the corresponding numbers were 15% (147 out of 976) for Eliquis compared with 24% (243 out of 997) for enoxaparin.
Slovenian: Pri bolnikih po kirurški zamenjavi kolena sta bila ta deleža 15 % (147 od 976) bolnikov, ki so jemali zdravilo Eliquis, in 24 % (243 od 997) bolnikov, ki so jemali enoksaparin.
English: In the prevention study in 2,482 patients, Eliquis was compared with placebo (a dummy treatment) and its effectiveness was measured by looking at the number of patients who either had problems related to clotting in the veins or who died of any cause during treatment.
Slovenian: V študiji preprečevanja z 2 482 bolniki so zdravilo Eliquis primerjali s placebom (zdravilom brez učinkovine), njegovo učinkovitost pa so merili s številom bolnikov, ki so imeli težave zaradi strdkov v venah ali so med zdravljenjem iz katerega koli vzroka umrli.