FrancophonIA/ELRC3.0 huggingface dataset:
English: The adverse reaction profile was similar across all the respective adult studies: antiretroviral naïve patients (APV30002, ESS100732), protease inhibitor experienced (twice daily dosing, APV30003) patients.
Danish: Bivirkningsprofilen var ens i alle de respektive studier med voksne: behandlingsnaive patienter (APV30002, ESS100732) og patienter, der tidligere har været behandlet med proteasehæmmere (dosering 2 gange daglig, APV30003).
English: If you notice any of these symptoms: →Tell your doctor.
Danish: Hvis du får et eller flere af disse symptomer:  Fortæl det til lægen.
English: When antineoplastic agents that are metabolised by CYP3A are co-administered with fosamprenavir/ritonavir, plasma concentrations of these antineoplastic medications may be increased and could increase the risk of adverse events usually associated with these antineoplastic agents.
Danish: Når antineoplastiske midler, der metaboliseres af CYP3A, administreres samtidigt med fosamprenavir/ritonavir, kan plasmakoncentrationerne af disse antineoplastiske lægemidler øges og kunne øge risikoen for bivirkninger, der normalt er forbundet med disse antineoplastiske midler.
English: Telzir 700 mg film-coated tablets Fosamprenavir
Danish: Telzir 700 mg filmovertrukne tabletter Fosamprenavir
English: It may result in an increase in PDE5 inhibitor-associated adverse reactions, including hypotension, visual changes and priapism (refer to PDE5 inhibitor prescribing information).
Danish: Kan resultere i en øget risiko for PDE5-hæmmerassocierede bivirkninger, herunder hypotension, synsændringer og priapisme (se produktinformationen for PDE5hæmmer).
English: It may cause serious adverse reactions (see section 4.4).
Danish: Kan forårsage alvorlige bivirkninger (se pkt.
English: Ketoconazole 200 mg once daily for four days
Danish: Ketoconazol 200 mg en gang daglig i 4 dage
English: Ketoconazole: Cmax ↑ 25% Ketoconazole: AUC ↑ 2.69fold.
Danish: Ketoconazol: Cmax  25 % Ketoconazol: AUC  2,69 fold.
English: No FPV/RTV drug interaction studies dasatinib: ↑ expected nilotinib: ↑ expected ibrutinib: ↑ expected vinblastine: ↑ expected everolimus: ↑ expected (CYP3A4 inhibition)
Danish: Ingen FPV/RTV interaktionsstudier dasatinib:  forventet nilotinib:  forventet ibrutinib:  forventet vinblastin:  forventet everolimus:  forventet (CYP3A4 hæmning)
English: All patients in this study had failed treatment with a previous protease inhibitor regimen (defined as plasma HIV-1 RNA that never went below 1,000 copies/ml after at least 12 consecutive weeks of therapy, or initial suppression of HIV-1 RNA which subsequently rebounded to ≥ 1,000 copies/ml).
Danish: Alle patienter i dette studie havde tidligere oplevet behandlingssvigt på et proteasehæmmerregime (defineret som plasma hiv-1-RNA som aldrig kom under 1.000 kopier/ml efter mindst 12 konsekutive ugers behandling, eller som initial suppression af hiv-1-RNA med efterfølgende rebound til  1.000 kopier/ml).
English: Concomitant use of Telzir with simvastatin or lovastatin is contraindicated because of increased plasma concentrations of lovastatin and simvastatin which can increase the risk of myopathy, including rhabdomyolysis (see section 4.5).
Danish: Samtidig administration af Telzir og simvastatin eller lovastatin er kontraindiceret pga. øgede plasmakoncentrationer af simvastatin og lovastatin, hvilket kan øge risikoen for myopati, herunder rabdomyolyse (se pkt.
English: Treatment-emergent major or APV-associated protease mutations were observed in virus isolated from 2 patients.
Danish: Alvorlige proteasemutationer opstået under behandling eller APV-forbundet blev set i virus isoleret fra 2 patienter.
English: >100,000 copies/ml, n (%)
Danish: > 100.000 kopier/ml
English: Significant reductions in amprenavir Cmin observed may result in virological failure in patients.
Danish: Signifikant nedsat amprenavir Cmin er observeret, hvilket kan medføre virologisk svigt hos nogle patienter.
English: Children can take the adult dose of ritonavir capsules (100 mg twice daily) if they weigh at least 33 kg and can swallow the capsules whole.
Danish: Børn kan tage voksendosis af ritonavir kapsler (100 mg 2 gange daglig), hvis de vejer mindst 33 kg og kan sluge kapslerne hele.
English: Your doctor will decide if these medicines are suitable for you to take with Telzir and ritonavir.
Danish: Lægen vil afgøre, om medicinen kan tages sammen med Telzir og ritonavir.
English: Autoimmune disorders (such as Graves' disease) have also been reported to occur in the setting of immune reactivation; however, the reported time to onset is more variable and these events can occur many months after initiation of treatment (see section 4.4).
Danish: Autoimmune sygdomme (som f.eks. Graves´ sygdom og autoimmun hepatitis) er også blevet rapporteret i forbindelse med immunreaktivering; dog er den rapporterede tid til frembrud mere variabel, og frembrud kan forekomme mange måneder efter behandlingsstart (se pkt.
English: Lovastatin: ↑ expected Simvastatin: ↑ expected
Danish: Lovastatin:  forventet
English: mechanism of interaction is CYP3A4 inhibition by fosamprenavir/ritonavir.
Danish: Mekanismen for denne interaktion er CYP3A4hæmning af fosamprenavir/ritonavir.
English: Telzir in combination with low dose ritonavir is indicated for the treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infected adults, adolescents and children of 6 years and above in combination with other antiretroviral medicinal products.
Danish: Telzir i kombination med en lav dosis ritonavir er indiceret til behandling af hiv-1-inficerede voksne, unge og børn over 6 år i kombination med andre antiretrovirale lægemidler.
English: All Patients CD4-count <50
Danish: CD4-celletal < 50
English: A 10 ml graduated dosing syringe and an adapter are also included in the pack.
Danish: En 10 ml doseringssprøjte og en adapter er vedlagt i pakningen
English: The Summary of Product Characteristics of ritonavir must therefore be consulted prior to initiation of therapy with Telzir.
Danish: Produktresumeet for ritonavir skal derfor læses før påbegyndelse af behandlingen med Telzir.
English: Your doctor will monitor your blood glucose levels before and during treatment with Telzir.
Danish: Lægen vil måle dit blodsukker, inden du begynder behandling med Telzir og løbende, mens du er i behandling.
English: ADRENORECEPTOR ANTAGONIST Alfuzosin,
Danish: ALFA1-ANTAGONISTER Alfuzosin
English: Tablet or Oral suspension 700 mg (1 tablet or 14 ml suspension)
Danish: 700 mg (1 tablet eller 14 ml suspension)
English: (Induction and/or inhibition of CYP2C9 by RTV)
Danish: (RTV inducerer og/eller hæmmer CYP2C9)
English: For children weighing less than 39 kg, Telzir oral suspension is the recommended option for the most accurate dosing in children based on body weight (please refer to the Summary of Product Characteristics for Telzir oral suspension).
Danish: Børn, som vejer mindre end 39 kg, bør anvende Telzir oral suspension, idet den nøjagtige dosering til denne patientgruppe baseres på kropsvægt (se i produktresuméet for Telzir oral suspension).
English: Therapeutic concentration monitoring is recommended for immunosuppressant medicinal products (cyclosporine, tacrolimus, rapamycin) when co-administered with Telzir (see section 4.5).
Danish: Terapeutiske koncentrationsmålinger anbefales for immunosuppresive lægemidler (cyclosporin, tacrolimus, rapamycin), når disse administreres samtidig med Telzir (se pkt.
English: Tell your doctor or pharmacist if you're taking or have recently taken any other medicinesthese include herbal medicines or other medicines you bought without a prescription.
Danish: Fortæl altid lægen eller apotekspersonalet, hvis du bruger anden medicin eller har gjort det for nylig.
English: No studies on the effects of Telzir in combination with ritonavir on the ability to drive and use machines have been performed.
Danish: Der er ikke foretaget studier af virkninger på evnen til at føre motorkøretøj eller betjene maskiner for Telzir i kombination med ritonavir.
English: • maraviroc (used to treat HIV infection)
Danish: • maraviroc (mod hiv-infektion).
English: AAUCMB Mean Diff (97.5% CI)
Danish: AAUCMB gennemsnitlig forskel (97,5 % CI)
English: • Change in your body shape
Danish: • ændringer i kropsfacon
English: APV29005 enrolled 30 patients aged 6 to 11 (the majority of whom were treated with fosamprenavir / ritonavir 18/3 mg/kg twice daily or the adult tablet regimen) and 40 patients aged 12 to 18 (the majority of whom were treated with the adult tablet regimen).
Danish: APV29005 involverede 30 patienter mellem 6 og 11 år (hvoraf de fleste blev behandlet med 18 mg fosamprenavir/kg og 3 mg ritonavir/kg 2 gange daglig eller voksendoseringen) og 40 patienter mellem 12 og 18 år (hvoraf de fleste blev behandlet med voksendoseringen).
English: Telzir is also available as an oral suspension for use in patients unable to swallow tablets, and in paediatric patients less than 39 kg (please refer to the Summary of Product Characteristics for Telzir oral suspension).
Danish: Denne anvendes til patienter, som ikke kan synke tabletter, og til pædiatriske patienter, som vejer under 39 kg (se i produktresuméet for Telzir oral suspension).
English: When fosamprenavir and ritonavir are co-administered, the ritonavir metabolic drug interaction profile may predominate because ritonavir is a more potent CYP3A4 inhibitor.
Danish: Når fosamprenavir og ritonavir administreres samtidig vil ritonavirs metaboliske interaktion tilsyneladende dominere, idet ritonavir er en mere potent CYP3A4-hæmmer.
English: If you are breast-feeding, or thinking about breast-feeding: →Talk to your doctor immediately.
Danish: Hvis du ammer eller planlægger at amme:  Tal straks med lægen.
English: Herbal preparations containing St John's wort (Hypericum perforatum) must not be used while taking Telzir due to the risk of decreased plasma concentrations and reduced clinical effects of amprenavir (see section 4.5).
Danish: Naturprodukter indeholdende perikon (Hypericum perforatum) må ikke anvendes samtidig med Telzir på grund af risiko for fald i plasmakoncentrationen og risiko for reduceret klinisk effekt af fosamprenavir (se pkt.
English: Phenotypic resistance testing
Danish: Fænotype-resistens-test
English: Cmax ↓ 56% (-70%; -34%) AUC ↓ 54% (-66%; -37%) Cmin ↓ 54 % (-74%; -18%)
Danish: Cmax 56 % (-70 % til -34 %) AUC 54 % (-66 % til -37 %) Cmin 54 % (-74 % til -18 %)
English: As a general rule, when deciding to use antiretroviral agents for the treatment of HIV infection in pregnant women and consequently for reducing the risk of HIV vertical transmission to the newborn, the animal data (see section 5.3) as well as the clinical experience in pregnant women should be taken into account.
Danish: Som en generel regel bør data fra dyrestudier såvel som klinisk erfaring fra gravide medtages i overvejelserne i beslutningen om, hvorvidt antiretrovirale lægemidler skal anvendes i behandlingen af hiv-infektion hos gravide for at nedsætte risikoen for vertikal transmission af hiv til den nyfødte.
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant Summary of Product Characteristics for these medicinal products.
Danish: Ved samtidig behandling af hepatitis B eller C med antivirale midler henvises til produktresumeet for disse lægemidler.
English: • sildenafil, vardenafil or tadalafil (used to treat erectile dysfunction)
Danish: • sildenafil, vardenafil eller tadalafil (mod impotens)
English: The use of Telzir concomitantly with halofantrine or lidocaine (systemic) is not recommended.
Danish: Lægemidler - interaktioner Brugen af Telzir sammen med halofantrin eller lidocain (systemisk) kan ikke anbefales.
English: Drug-related adverse reactions were more common in APV20003 (57%) where subjects received once daily fosamprenavir / ritonavir when compared to APV29005 (33%) where subjects received twice daily fosamprenavir / ritonavir.
Danish: Lægemiddelrelaterede bivirkninger var mere almindelige i APV20003 (57 %), hvor patienterne fik behandling med fosamprenavir/ritonavir en gang daglig sammenlignet med APV29005 (33 %), hvor patienterne fik fosamprenavir/ritonavir 2 gange daglig.
English: Tricyclic antidepressant: ↑ expected
Danish: Tricykliske antidepressiva:  forventet
English: Additionally, both amprenavir, the active metabolite of fosamprenavir, and ritonavir are primarily metabolised in the liver by CYP3A4.
Danish: Både fosamprenavirs aktive metabolit, amprenavir, og ritonavir metaboliseres i leveren af CYP3A4.
English: Etravirine
Danish: Etravirin
English: EXP Discard 28 days after first opening
Danish: Kassér den orale suspension 28 dage efter første åbning af flasken
English: This product also contains preservatives: methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216), see leaflet for further information
Danish: Dette lægemiddel indeholder konserveringsmidler: Methylparahydroxybenzoat (E218) og propylparahydroxybenzoat (E216), se indlægssedlen for flere oplysninger
English: During attempts to overcome the decreased exposure by increasing the dose of other protease inhibitors with ritonavir, a high frequency of liver reactions was seen.
Danish: Forsøg på at modvirke denne reduktion i amprenavir-AUC, ved at øge dosis af andre proteasehæmmere sammen med ritonavir, resulterede i en højere forekomst af leverpåvirkninger.
English: The
Danish: a
English: Discard 28 days after first opening.
Danish: Kassér den orale suspension 28 dage efter første åbning af flasken.
English: Your doctor may lower your dose of Telzir and ritonavir depending on the amount of liver damage.
Danish: Lægen kan nedsætte dosis af Telzir og ritonavir i forhold til din leverfunktion.
English: Metabolic parameters: weight and levels of blood lipids and glucose may increase during antiretroviral therapy (see section 4.4).
Danish: Metaboliske parameter: Kropsvægt og niveauerne af lipid og glucose i blodet kan stige under antiretroviral behandling (se pkt.
English: It is very important that you take the full daily dose of Telzir and ritonavir as prescribed by your doctor.
Danish: Det er vigtigt, at du tager hele dagens dosis af både Telzir og ritonavir.
English: Calcium chloride dihydrate Artificial grape bubblegum flavour Natural peppermint flavour Purified water
Danish: Calciumchloriddihydrat Syntetisk grape-tyggegummismagsstof Naturligt pebermyntesmagsstof Renset vand
English: Predicted exposures are based on extrapolation from data observed following administration of fosamprenavir 300 mg twice daily with ritonavir 100 mg once daily in subjects with moderate hepatic impairment.
Danish: Den forventede eksponering er baseret på ekstrapolation af data efter administration af fosamprenavir 300 mg 2 gange daglig med ritonavir 100 mg én gang daglig hos personer med moderat nedsat leverfunktion.
English: Loose stools, nausea, vomiting, abdominal pain
Danish: Løs afføring, kvalme, opkastning, mavesmerter
English: Telzir with ritonavir should be used with caution and at reduced doses in adults with mild, moderate or severe hepatic impairment (see section 4.2).
Danish: Telzir i kombination med ritonavir bør anvendes med forsigtighed og i reducerede doser til voksne med let, moderat eller svært nedsat leverfunktion (se pkt.
English: Taking Telzir and ritonavir while taking the contraceptive pill may harm your liver and may stop the contraceptive from working properly.
Danish: Hvis du tager Telzir og ritonavir samtidig med p-piller, kan det skade din lever og nedsætte virkningen af p-pillerne.
English: Telzir with ritonavir must not be co-administered with medicinal products with narrow therapeutic windows that are highly dependent on CYP2D6 metabolism, e.g. flecainide and propafenone (see section 4.5).
Danish: Samtidig administration af Telzir og ritonavir må ikke kombineres med lægemidler, som har smalt terapeutisk vindue og som i høj grad er afhængig af CYP2D6 metabolisme, f.eks. flecainid og propafenon (se pkt.
English: Careful monitoring of the therapeutic and adverse reactions of tricyclic antidepressants is recommended (see section
Danish: Effekten og bivirkningerne af tricykliske antidepressiva skal omhyggelig overvåges (se pkt.
English: The principal route of amprenavir and ritonavir elimination is hepatic metabolism.
Danish: Den primære elimineringsvej for amprenavir og ritonavir er via leveren.
English: Children and adolescent patients above the age of six
Danish: Børn og unge over 6 år
English: Telzir should be permanently discontinued in case of severe rash, or in case of rash of moderate intensity with systemic or mucosal symptoms (see section 4.8).
Danish: Telzir bør seponeres permanent i tilfælde af sværere udslæt eller i tilfælde af moderat udslæt ledsaget af systemiske eller mucosale symptomer (se pkt.
English: If a patient is already taking St John's wort, check amprenavir, ritonavir and HIV RNA and stop St John's wort.
Danish: Hvis en patient allerede tager perikon, skal niveauet for amprenavir, ritonavir og hiv-RNA tjekkes og perikon seponeres.
English: The pharmacokinetics of fosamprenavir have not been studied in this patient population (see section 5.2).
Danish: Farmakokinetikken for fosamprenavir er ikke undersøgt hos patienter over 65 år (se pkt.
English: In rats only there was an increase in interstitial cell hyperplasia in males at exposure levels equivalent to 0.5-fold those in humans, and an increase in uterine endometrial adenocarcinoma in females at an exposure level equivalent to 1.1-fold those in humans.
Danish: Hos hanrotter sås en højere forekomst af interstitiel celle-hyperplasi ved eksponeringsniveauer 0,5 gange større end den humane, og i hunrotter sås en stigning i uterin endometrial adenocarcinomaer ved eksponeringsniveauer 1,1 gange større end den humane.
English: Telzir must not be administered concurrently with medicinal products with narrow therapeutic windows that are substrates of cytochrome P450 3A4 (CYP3A4), e.g. alfuzosin, amiodarone, astemizole, bepridil, cisapride, dihydroergotamine, ergotamine, pimozide, quetiapine, quinidine, terfenadine, oral midazolam (for caution on parenterally administered midazolam, see section 4.5), oral triazolam, sildenafil used for the treatment of pulmonary arterial hypertension (for use of sildenafil in patients with erectile dysfunction, see sections 4.4 and 4.5).
Danish: Telzir må ikke administreres samtidig med lægemidler, som har et smalt terapeutisk vindue, og som er substrater for CYP3A4, f.eks. alfuzosin, amiodaron, astemizol, bepridil, cisaprid, dihydroergotamin, ergotamin, pimozid, quetiapin, quinidin, terfenadin, oral midazolam (se pkt.
English: The recommended dose is 0.36 ml/kg of Telzir oral suspension (18 mg per kg fosamprenavir) twice daily with 3 mg/kg ritonavir oral solution twice daily.
Danish: Den anbefalede dosis er 0,36 ml/kg Telzir oral suspension (18 mg pr. kg fosamprenavir) 2 gange daglig sammen med 3 mg/kg ritonavir oral opløsning 2 gange daglig.
English: Based on data with other protease inhibitors plasma concentrations of midazolam are expected to be significantly higher when midazolam is given orally.
Danish: Data for andre CYP3A4hæmmere indikerer, at midazolamkoncentrationen bliver signifikant højere, når midazolam gives oralt.
English: • if you are allergic to fosamprenavir, amprenavir or any of the other ingredients of this medicine
Danish: • hvis du er allergisk over for fosamprenavir, amprenavir eller et af de øvrige indholdsstoffer i dette lægemiddel (angivet i punkt 6) eller over for ritonavir
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON FOR ORAL SUSPENSION
Danish: YDRE KARTON TIL ORAL SUSPENSION
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 12 July 2004
Danish: DATO FOR FØRSTE MARKEDSFØRINGSTILLADELSE/FORNYELSE AF TILLADELSEN
English: Co-administration of TELZIR/ritonavir with alfuzosin is contraindicated (see section 4.3).
Danish: Samtidig administration af Telzir/ritonavir og alfuzosin er kontraindiceret (se pkt.
English: • dolutegravir (used to treat HIV infection)
Danish: • dolutegravir (mod hiv-infektion)
English: Ergonovine: ↑ expected Ergotamine: ↑ expected Methylergonovine: ↑ expected
Danish: Dihydroergotamin:  forventet Ergometrin:  forventet Ergotamin:  forventet Methylergometrin:  forventet
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2).
Danish: Lægemidlet må kun udleveres efter ordination på en recept udstedt af en begrænset lægegruppe (se. bilag I: Produktresumé, pkt.
English: Telzir is a type of medicine known as an anti-retroviral.
Danish: Telzir er et antiretroviralt lægemiddel.
English: PDE5 INHIBITORS
Danish: PDE5-HÆMMERE
English: You may have problems with your bones
Danish: Problemer med knoglerne
English: If overdose occurs, the patient should be monitored for evidence of toxicity (see section 4.8) and standard supportive treatment applied as necessary.
Danish: Hvis overdosering forekommer, bør patienten overvåges for tegn på toksicitet (se pkt.
English: Cmax ↓ 25% (-41%; -4%) AUC ↓ 25% (-42%; -3%) Cmin ↓ 33% (-50%; -10%)
Danish: Cmax 25 % (-41 % til -4 %) AUC 25 % (-42 % til -3 %) Cmin 33 % (-50 % til -10 %)
English: Maraviroc 300 mg twice daily
Danish: Maraviroc 300 mg 2 gange daglig
English: Hepatitis C virus (HCV) Direct-Acting Antivirals: When hepatitis C virus direct-acting antiviral (DAA) drugs, which are metabolised by CYP3A4 or are inducers/inhibitors of CYP3A4, are coadministered with fosamprenavir/ritonavir, altered plasma concentrations of medications are expected due to inhibition or induction of CYP3A4 enzyme activity (see section 4.3 and 4.5).
Danish: Hepatitis C-virus (HCV) direkte virkende antivirale stoffer: Når hepatitis C-virus direkte virkende antivirale stoffer, som metaboliseres af CYP3A4, eller som er induktorer/hæmmere af CYP3A4, administreres samtidigt med fosamprenavir/ritonavir, kan ændrede plasmakoncentrationer forventes pga. hæmning eller induktion af CYP3A4-enzymaktivitet (se pkt.
English: Therapeutic concentration monitoring is recommended for tricyclic antidepressants (e.g. desipramine and nortriptyline) when co-administered with Telzir (see section 4.5).
Danish: Terapeutiske koncentrationsmålinger anbefales for tricykliske antidepressiva (f.eks. desipramin og nortriptylin), når disse administreres samtidig med Telzir (se pkt.
English: ViiV Healthcare Trading Services UK Limited 12 Riverwalk,
Danish: ViiV Healthcare Trading Services UK Limited 12 Riverwalk, Citywest Business Campus Dublin 24,
English: HDPE bottles with a child resistant polypropylene closure containing 60 tablets.
Danish: HDPE flaske med børnesikret låg af polypropylen.
English: Efficacy Outcomes
Danish: Virkningsmekanisme
English: The plasma amprenavir pharmacokinetics were evaluated in a 14 day repeat-dose study in HIV-1 infected adult subjects with mild, moderate, or severe hepatic impairment receiving fosamprenavir with ritonavir compared to matched control subjects with normal hepatic function.
Danish: Amprenavirs farmakokinetik i plasma blev undersøgt i et 14-dages ”repeat-dose”-studie med hiv-1inficerede voksne personer med let, moderat eller svært nedsat leverfunktion.
English: Compared to the historical adult population receiving fosamprenavir / ritonavir 700 / 100 mg twice daily, 12 to 18 year old subjects had 20 % lower plasma APV AUC(024), 23 % lower Cmax, and 20 % lower Cmin values.
Danish: Sammenlignet med historiske data for voksne behandlet med samme doser havde de 12 til 18-årige 20 % lavere plasma APV AUC(0-24), 23 % lavere Cmax, og 20 % lavere Cmin-værdier.
English: • atorvastatin up to 20 mg per day (used to lower cholesterol)
Danish: • atorvastatin op til 20 mg om dagen (mod forhøjet kolesterol i blodet)
English: The current (July 2006) ANRS AC-11 algorithm for fosamprenavir / ritonavir defines resistance as the presence of the mutations V32I+I47A/V, or I50V, or at least four mutations among: L10F/I/V, L33F, M36I, I54A/L/M/S/T/V,
Danish: Den nuværende (juli 2006) ANRS AC-11-algoritme for fosamprenavir/ritonavir definerer resistens som tilstedeværelsen af mutationerne V32I+I47A/V, eller I50V eller mindst fire af følgende mutationer: L10F/I/V, L33F, M36I, I54A/L/M/S/T/V, I62V, V82A/C/F/G, I84V og L90M.