FrancophonIA/ELRC3.0 huggingface dataset:
English: A selective inhibitor of CYP3A4, ketoconazole (200 mg daily), increased tadalafil (10 mg) exposure (AUC) 2-fold and Cmax by 15 %, relative to the AUC and Cmax values for tadalafil alone.
Croatian: (200 mg na dan) udvostručio je izloženost (AUC) tadalafilu (10 mg) i povećao Cmax za 15 % u odnosu na vrijednosti AUC-a i Cmax kod primjene samog tadalafila.
English: INFORMATION IN BRAILLE cialis 5 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU cialis 5 mg
English: A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered.
Croatian: Prije razmatranja farmakološkog liječenja treba uzeti anamnezu bolesnika te obaviti fizikalni pregled kako bi se dijagnosticirala erektilna disfunkcija i utvrdili njezini mogući uzroci.
English: Suomi/Finland Oy Eli Lilly Finland Ab Puh/Tel: + 358-(0) 9 85 45 250
Croatian: Puh/Tel: + 358-(0) 9 85 45 250
English: The recommended dose is 5 mg, taken at approximately the same time every day with or without food.
Croatian: Benigna hiperplazija prostate u odraslih muškaraca Preporučena doza je 5 mg, a uzima se svakodnevno otprilike u isto doba dana, s hranom ili bez nje.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 20 mg tadalafil
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna tableta sadrži 20 mg tadalafila.
English: CIALIS 20 mg film-coated tablets
Croatian: CIALIS 20 mg filmom obložene tablete tadalafil
English: A. MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE Name and address of the manufacturers responsible for batch release Lilly S.A., Avda.
Croatian: PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET Naziv(i) i adresa(e) proizvođača odgovornog(ih) za puštanje serije lijeka u promet Lilly S.A., Avda. de la Industria 30, 28108 Alcobendas, Madrid, Španjolska
English: How to store CIALIS
Croatian: Moguće nuspojave Kako čuvati CIALIS
English: Visual field defect, Swelling of eyelids, Conjunctival hyperaemia, Nonarteritic anterior ischemic optic neuropathy (NAION) 2, Retinal vascular occlusion2
Croatian: Poremećaji oka zamagljen vid, osjeti opisani kao bol u oku poremećaj vidnog polja, oticanje vjeđa, hiperemija konjunktive, nearterijska prednja ishemijska optička neuropatija (NAION)2, okluzija krvnih žila mrežnice2
English: Facial oedema2, Sudden cardiac death1, 2
Croatian: Opći poremećaji i reakcije na mjestu primjene bol u prsnom košu1, periferni edem, umor edem lica2, iznenadna srčana smrt1, 2
English: MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/001-005, 009
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/02/237/001-005, 009
English: Light yellow and almond shaped tablets, marked "C 5" on one side.
Croatian: Svijetložute tablete u obliku badema, s oznakom "C 5" na jednoj strani.
English: CIALIS 10 mg film-coated tablets
Croatian: CIALIS 10 mg filmom obložene tablete tadalafil
English: NAME OF THE MEDICINAL PRODUCT CIALIS 10 mg tablets tadalafil
Croatian: NAZIV LIJEKA CIALIS 10 mg tablete tadalafil
English: MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/001
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/02/237/001
English: Hypotension3, Hypertension
Croatian: Krvožilni poremećaji crvenilo praćeno osjećajem užarenosti hipotenzija3, hipertenzija
English: MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/002-005, 009
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/02/237/002-005, 009
English: Once-a-day dosing has not been evaluated in patients with hepatic impairment; therefore if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician (see sections 4.4 and 5.2).
Croatian: Ako se propisuje tadalafil, liječnik koji ga propisuje mora pažljivo procijeniti omjer koristi i rizika liječenja za svakog pojedinog bolesnika (vidjeti dijelove 4.4 i 5.2).
English: NAME OF THE MEDICINAL PRODUCT CIALIS 2.5 mg film-coated tablets
Croatian: NAZIV LIJEKA CIALIS 2,5 mg filmom obložene tablete
English: NAME OF THE MEDICINAL PRODUCT CIALIS 2.5 mg tablets tadalafil
Croatian: NAZIV LIJEKA CIALIS 2,5 mg tablete tadalafil
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 10 mg tadalafil
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna tableta sadrži 10 mg tadalafila.
English: CIALIS 2.5 mg film-coated tablets Tadalafil
Croatian: CIALIS 2,5 mg filmom obložene tablete tadalafil
English: de la Industria 30, 28108 Alcobendas, Madrid, Spain The printed package leaflet of the medicinal product must state the name and address of the manufacturer responsible for the release of the concerned batch.
Croatian: Na tiskanoj uputi o lijeku mora se navesti naziv i adresa proizvođača odgovornog za puštanje navedene serije u promet.
English: Skin and subcutaneous tissue disorders
Croatian: Poremećaji bubrega i mokraćnog sustava hematurija
English: MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/006
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/02/237/006
English: CIALIS 5 mg film-coated tablets Tadalafil
Croatian: CIALIS 5 mg filmom obložene tablete tadalafil
English: NAME OF THE MEDICINAL PRODUCT CIALIS 5 mg film-coated tablets
Croatian: NAZIV LIJEKA CIALIS 5 mg filmom obložene tablete
English: NAME OF THE MEDICINAL PRODUCT CIALIS 5 mg tablets tadalafil
Croatian: NAZIV LIJEKA CIALIS 5 mg tablete tadalafil
English: When the submission of a PSUR and the update of a RMP coincide, they should be submitted at the same time.
Croatian: (RMP), dokumenti mogu biti podneseni istodobno.
English: - The other ingredients are: Tablet core: lactose monohydrate (see end of section 2), croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate.
Croatian: Jezgra tablete: laktoza hidrat umrežena karmelozanatrij hidroksipropilceluloza mikrokristalična celuloza natrijev laurilsulfat magnezijev stearat
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 5 mg tadalafil
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna tableta sadrži 5 mg tadalafila.
English: Eli Lilly farmacevtska družba, d.o.o.
Croatian: Lilly Portugal Produtos Farmacêuticos, Lda.
English: Thus, in a patient prescribed any dose of CIALIS (2.5 mg-20 mg), where nitrate administration is deemed medically necessary in a life-threatening situation, at least 48 hours should have elapsed after the last dose of CIALIS before nitrate administration is considered.
Croatian: 20 mg), a u kojih je primjena nitrata medicinski nužna u situaciji opasnoj po život, treba proći najmanje
English: What CIALIS looks like and contents of the pack CIALIS 10 mg is a light yellow film-coated tablet in the shape of an almond and has "C 10" marked on one side.
Croatian: CIALIS 10 mg je svijetložuta filmom obložena tableta u obliku badema koja s jedne strane ima oznaku "C 10".
English: What CIALIS looks like and contents of the pack CIALIS 5 mg is a light yellow film-coated tablet in the shape of an almond and has "C 5" marked on one side.
Croatian: CIALIS 5 mg je svijetložuta filmom obložena tableta u obliku badema koja s jedne strane ima oznaku "C 5".
English: How to take CIALIS once-a-day 1.
Croatian: Kako uzimati CIALIS jedanput na dan
English: Once-a-day administration has not been evaluated in patients with hepatic insufficiency.
Croatian: Primjena jedanput na dan nije ispitana u bolesnika s insuficijencijom jetre.
English: Yellow and almond shaped tablets, marked "C 20" on one side.
Croatian: CIALIS 20 mg filmom obložene tablete Žute tablete u obliku badema, s oznakom "C 20" na jednoj strani.
English: Eli Lilly Nederland B.V. Tel: + 31-(0) 30 60 25 800
Croatian: Eli Lilly farmacevtska družba, d.o.o. Tel: +386 (0)1 580 00 10
English: EXP.
Croatian: Tel.
English: Haematuria
Croatian: OBLIK
English: Lilly Deutschland GmbH Tel. + 49-(0) 6172 273 2222
Croatian: Slovenská republika Eli Lilly Slovakia, s.r.o. Tel: +421 220 663 111
English: Visual defects and cases of NAION have been reported in connection with the intake of CIALIS and other PDE5 inhibitors.
Croatian: Kod uzimanja lijeka CIALIS i drugih inhibitora PDE5 prijavljene su smetnje vida i slučajevi nearterijske prednje ishemijske optičke neuropatije.
English: LIST OF EXCIPIENTS lactose
Croatian: Tablični prikaz nuspojava
English: NAME OF THE MEDICINAL PRODUCT CIALIS 20 mg film-coated tablets tadalafil
Croatian: Uputa o lijeku: Informacije za korisnika CIALIS 20 mg filmom obložene tablete tadalafil
English: Ear and labyrinth disorders
Croatian: Poremećaji uha i labirinta tinitus iznenadan gubitak sluha
English: Adults and children older than 1 year
Croatian: Odrasli i djeca starija od 1 godine
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION 14 January 2016
Croatian: DATUM PRVOG ODOBRENJA / DATUM OBNOVE ODOBRENJA 14. siječnja 2016.
English: You may be more susceptible to infections.
Croatian: Možete biti osjetljiviji na infekcije.
English: The mechanism leading to this reaction is unknown.
Croatian: Mehanizam koji dovodi do te reakcije nije poznat.
English: There is no specific antidote.
Croatian: Nema posebnog antidota.
English: These events are usually transient.
Croatian: Ti su događaji obično prolazni.
English: In addition, it is especially important to tell your doctor if you are also using any of the following medicines:
Croatian: Osim toga, posebno je važno da liječniku kažete ako također uzimate sljedeće lijekove:
English: Your doctor decides on the dose you receive.
Croatian: Liječnik odlučuje o dozi koju ćete primiti.
English: Results are shown in table 4.
Croatian: Rezultati su prikazani u tablici 4.
English: It should only be given in a hospital setting where appropriate resuscitation equipment is available.
Croatian: Smije se davati samo u bolničkom okruženju gdje je na raspolaganju odgovarajuća oprema za oživljavanje.
English: Adults and other special populations
Croatian: Odrasli i druge posebne populacije
English: The causes of these nervous system disorders are unclear.
Croatian: Uzroci tih poremećaja živčanog sustava nisu jasni.
English: Spectrila will not be used:
Croatian: Spectrila neće biti primijenjena:
English: Acute pancreatitis has developed in less than 10 % of patients.
Croatian: Akutni pankreatitis razvio se u manje od 10% bolesnika.
English: This effect was most prominent with a treatment interval of about 120 hours.
Croatian: Taj je učinak bio najizraženiji uz interval liječenja od otprilike 120 sati.
English: Read all of this leaflet carefully before you are given this medicine because it contains important information for you.
Croatian: Pažljivo pročitajte cijelu uputu prije nego počnete primati ovaj lijek jer sadrži Vama važne podatke.
English: Treatment is symptomatic and supportive.
Croatian: Liječenje je simptomatsko i potporno.
English: Time to Cmax
Croatian: Vrijeme do Cmax
English: Volume of distribution
Croatian: Volumen distribucije
English: Tell your doctor if you are using, have recently used or might use any other medicines.
Croatian: Obavijestite svog liječnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: White powder.
Croatian: Bijeli prašak.
English: The syndrome is generally self-limiting.
Croatian: Sindrom je obično samoograničavajući.
English: Both procedures, however, do not allow for predicting accurately which patients will experience an allergic reaction.
Croatian: Oba postupka, međutim, ne omogućuju točno predviđanje koji bolesnik će razviti alergijsku reakciju.
English: UNIQUE IDENTIFIER - 2D BARCODE <2D barcode carrying the unique identifier included.>
Croatian: 17. JEDINSTVENI IDENTIFIKATOR - 2D BARKOD <Sadrži 2D barkod s jedinstvenim identifikatorom.>
English: If necessary, your doctor will treat your symptoms and will give you supportive care.
Croatian: Ako je potrebno, liječnik će liječiti simptome koje imate i pružiti potpornu skrb.
English: It is usually given with other anti-cancer medicines.
Croatian: Obično se primjenjuje s drugim lijekovima protiv raka.
English: Asparagine depletion in serum was complete in 11 of 12 patients (92%).
Croatian: Deplecija asparagina u serumu bila je potpuna u 11 od 12 bolesnika (92%).
English: Other medicines and Spectrila
Croatian: Drugi lijekovi i Spectrila
English: Methotrexate (MTX)
Croatian: Metotreksat (MTX)
English: There have been isolated reports of fatal outcomes.
Croatian: Postoje izolirane prijave smrtnih ishoda.
English: The risk of thrombosis seems to be higher than the risk of bleeding.
Croatian: Čini se da je rizik od tromboze veći od rizika od krvarenja.
English: Area under the curve (AUC0-72h)
Croatian: Površina ispod krivulje (AUC0-72h)
English: Not known Infections
Croatian: Nepoznato infekcije
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.
Croatian: Ako ste trudni ili dojite, mislite da biste mogli biti trudni ili planirate imati dijete, obratite se svom liječniku za savjet prije nego uzmete ovaj lijek.
English: What Spectrila is and what it is used for
Croatian: Što je Spectrila i za što se koristi
English: Before and during treatment with Spectrila your doctor will carry out blood tests.
Croatian: Prije i tijekom liječenja Spectrilom, liječnik će Vam provesti pretrage krvi.
English: Warnings and precautions Talk to your doctor or nurse before you are given Spectrila.
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku ili medicinskoj sestri prije nego što primite Spectrilu.
English: A previous intracutaneous test or a small intravenous test dose can be used.
Croatian: Prethodno se može provesti intrakutani test ili dati mala intravenska probna doza.
English: • if you have severe liver function problems,
Croatian: • ako imate teške probleme s funkcijom jetre,
English: Spectrila is available in packs containing 1 or 5 vials.
Croatian: Spectrila je dostupna u pakiranjima koja sadrže 1 ili 5 bočica.
English: Recommended control examinations for patients of all age groups
Croatian: Preporučene kontrolne pretrage za bolesnike svih dobnih skupina
English: Tell your doctor immediately and stop taking Spectrila if you experience:
Croatian: Odmah obavijestite liječnika i prestanite primati Spectrilu ako se u Vas pojavi:
English: What Spectrila contains
Croatian: Što Spectrila sadrži
English: All 12 patients (100 %) were in CR after induction treatment.
Croatian: Svih 12 bolesnika (100%) bilo je u potpunoj remisiji poslije indukcijskog liječenja.
English: • mild tremor (shaking) of the fingers
Croatian: • blagi tremor (drhtanje) prstiju
English: Maximum serum concentration (Cmax)
Croatian: Maksimalna koncentracija u serumu (Cmax)
English: As a precautionary measure it is recommended to wait for three months after completion of treatment.
Croatian: Kao mjera opreza preporučuje se pričekati tri mjeseca nakon završetka terapije.
English: • if you are allergic to asparaginase or to any of the other ingredients of this medicine (listed in section 6),
Croatian: • ako ste alergični na asparaginazu ili neki drugi sastojak ovog lijeka (naveden u dijelu 6),
English: One unit (U) is defined as the quantity of enzyme required to liberate one µmol ammonia per minute at pH 7.3 and 37°C.
Croatian: Jedna jedinica (U) definirana je kao količina enzima potrebna da se oslobodi jedan µmol amonijaka u minuti pri pH 7,3 na 37 °C.
English: You may be given anti-allergic medicines and, if necessary, medicines to stabilise your circulation.
Croatian: Možda ćete dobiti lijekove protiv alergije i, ako je potrebno, lijekove za stabilizaciju krvotoka.
English: The duration of treatment depends on the specific chemotherapy protocol that is used to treat your disease.
Croatian: Trajanje liječenja ovisi o specifičnom kemoterapijskom protokolu koji se provodi za liječenje Vaše bolesti.
English: - age 6 - 12 months:
Croatian: - u dobi 6 - 12 mjeseci:
English: Spectrila can induce antibodies of different immunoglobulin classes (IgG, IgM, IgE).
Croatian: Spectrila može potaknuti stvaranje protutijela različitih razreda imunoglobulina (IgG, IgM, IgE).
English: If you were given more Spectrila than you should If you think that you received too much Spectrila, tell your doctor or nurse as soon as possible.
Croatian: Ako ste primili više Spectrile nego što ste trebali Ako mislite da ste primili previše Spectrile, obratite se što prije liječniku ili medicinskoj sestri.
English: This is important as Spectrila may increase the side effects of other medicines through its effect on the liver which plays an important role in removing medicines from the body.
Croatian: To je važno jer Spectrila može povećati nuspojave drugih lijekova svojim učinkom na jetru, što ima važnu ulogu u uklanjanju lijekova iz tijela.
English: • increased blood sugar values.
Croatian: • povišene vrijednosti šećera u krvi.
English: OTHER Store in a refrigerator.
Croatian: Čuvati u hladnjaku.
English: • if you have or previously had inflammation of the pancreas (pancreatitis),
Croatian: • ako imate ili ste prije imali upalu gušterače (pankreatitis),
English: Thereafter, asparagine serum levels increased again and returned to normal values within 1 - 3 weeks.
Croatian: Kasnije su se razine asparagina u serumu ponovno povećale i vratile na normalne vrijednosti unutar 1 - 3 tjedna.
English: If the medicine is not used immediately, the user preparing this medicine is responsible for storage times and conditions to ensure sterility of the product.
Croatian: Ako se lijek ne primijeni odmah, korisnik koji priprema lijek odgovoran je za vrijeme i uvjete čuvanja kojima se mora osigurati sterilnost lijeka.
English: RPLS is treated symptomatically, including measures to treat any seizures.
Croatian: RPLS se liječi simptomatski, uključujući mjere za liječenje bilo kakvih napadaja.
English: Asparaginase is distributed mainly within the intravascular space.
Croatian: Asparaginaza se distribuira uglavnom unutar intravaskularnog prostora.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 °C - 8 °C unless reconstitution/dilution has taken place in controlled and validated aseptic conditions.
Croatian: Ako se ne primijeni odmah, vrijeme i uvjeti čuvanja lijeka prije same primjene odgovornost su korisnika i obično ne bi trebalo biti dulje od 24 sata na temperaturi 2 °C - 8 °C osim ako je rekonstitucija/razrjeđivanje provedeno u kontroliranim i validiranim aseptičnim uvjetima.
English: What you need to know before you are given Spectrila
Croatian: Što morate znati prije nego počnete primati Spectrilu
English: • The medicine also contains sucrose.
Croatian: • Lijek sadrži i saharozu.
English: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Croatian: Učestalosti prikazane u ovoj tablici definirane su prema sljedećem pravilu: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000); nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Table 4: Pharmacokinetic parameters of Spectrila in 14 children/adolescents
Croatian: Tablica 4: Farmakokinetički parametri Spectrile u 14 djece/adolescenata Parametar
English: Keep the vial in the outer carton in order to protect from light.
Croatian: Bočicu čuvati u vanjskoj kutiji radi zaštite od svjetlosti.
English: The probability of the occurrence of allergic reactions increases with the number of administered doses; however, in very rare cases reactions can occur at the first dose of asparaginase.
Croatian: Vjerojatnost pojave alergijskih reakcija raste s brojem primijenjenih doza; međutim, u vrlo rijetkim slučajevima reakcije se mogu pojaviti već nakon prve doze asparaginaze.
English: Intravenous use after further dilution.
Croatian: Intravenska primjena nakon daljnjeg razrjeđivanja.
English: • mild to moderate reduction in all blood cell counts
Croatian: • blago do umjereno smanjenje broja svih krvnih stanica
English: Increased blood sugar values may require treatment with intravenous fluids and/or insulin.
Croatian: Povišene vrijednosti šećera u krvi mogu zahtijevati liječenje intravenskim tekućinama i/ili inzulinom.
English: Reconstituted and diluted solution
Croatian: Rekonstituirana i razrijeđena otopina
English: • loss of appetite or weight loss
Croatian: • gubitak apetita ili gubitak tjelesne težine
English: The lower median activity level on day 33 compared to the former two measurements was in part due to the fact that this last serum sample was taken 4 days after the last infusion of asparaginase instead of three days on the other occasions.
Croatian: Niži medijan za razinu aktivnosti 33. dana u usporedbi s prethodna dva mjerenja djelomično je posljedica činjenice da je taj posljednji uzorak seruma uzet 4 dana nakon posljednje infuzije asparaginaze umjesto nakon 3 dana u drugim slučajevima.
English: Therefore, they require asparagine which diffuses from the extracellular environment.
Croatian: Stoga im je potreban asparagin koji difundira iz izvanstanične okoline.
English: This syndrome is characterised in magnetic resonance imaging (MRI) by reversible (from a few days to months) lesions/oedema, primarily in the posterior region of the brain.
Croatian: Taj sindrom očituje se na snimkama magnetske rezonancije (MRI) reverzibilnim (od nekoliko dana do nekoliko mjeseci) lezijama/edemom, prvenstveno u posteriornoj regiji mozga.
English: This regimen has been shown to reduce the gastrointestinal and haematological effects of methotrexate.
Croatian: Pokazalo se da taj režim smanjuje gastrointestinalne i hematološke učinke metotreksata.
English: Pharmacotherapeutic group: Antineoplastic agents; Other antineoplastic agents ATC code: L01XX02
Croatian: Farmakoterapijska skupina: antineoplastični lijekovi; drugi antineoplastični lijekovi, ATK oznaka: L01XX02
English: 6 22880 Wedel Germany
Croatian: 6 22880 Wedel Njemačka
English: Approximately half of the thrombotic events is localised in cerebral vessels.
Croatian: Otprilike polovica trombotskih događaja lokalizirana je u krvnim žilama mozga.
English: However, treatment with other chemotherapeutic agents should also be taken into consideration.
Croatian: Međutim, treba uzeti u obzir i liječenje drugim kemoterapijskim lijekovima.
English: Since Spectrila is usually used in combination therapy with other antineoplastic agents, the demarcation from undesirable effects of other medicinal products is often difficult.
Croatian: Budući da se Spectrila obično koristi u kombiniranoj terapiji s drugim antineoplastičnim lijekovima, često je teško odrediti granicu neželjenih učinaka drugih lijekova.
English: Spectrila is prepared and given by healthcare personnel.
Croatian: Spectrilu priprema i primjenjuje zdravstveno osoblje.
English: To avoid this, vincristine is usually given 3 - 24 hours before asparaginase.
Croatian: Da bi se to izbjeglo, vinkristin se obično daje u razdoblju od 3 do 24 sata prije asparaginaze.
English: Spectrila is used as part of a combination therapy.
Croatian: Spectrila se primjenjuje kao dio kombinirane terapije.
English: • diabetic ketoacidosis (complication due to uncontrolled blood sugar)
Croatian: • dijabetička ketoacidoza (komplikacija zbog nekontrolirane razine šećera u krvi)
English: Efficacy and safety of Spectrila have not been established in Philadelphia chromosome-positive patients.
Croatian: Djelotvornost i sigurnost primjene Spectrile nije ustanovljena u bolesnika pozitivnih na Philadelphia kromosom.
English: Each pack contains either 1 or 5 vials.
Croatian: Jedno pakiranje sadrži 1 ili 5 bočica.
English: In such cases, a switch to a different asparaginase preparation should be considered.
Croatian: U tim slučajevima potrebno je razmisliti o prijelazu na neki drugi pripravak asparaginaze.
English: Normal cells can make asparagine for themselves, while some cancer cells cannot.
Croatian: Normalne stanice mogu same stvarati asparagin, dok neke stanice raka to ne mogu.
English: Data on efficacy and safety of Spectrila in adults are limited.
Croatian: Podaci o djelotvornosti i sigurnosti Spectrile u odraslih su ograničeni.