FrancophonIA/ELRC3.0 huggingface dataset:
English: If you're breast-feeding, or thinking about breast-feeding:
Slovenian: Če dojite ali razmišljate o dojenju:
English: Recent findings indicate that exposure in children <6 years of age may be reduced by about 30 % compared with other age groups.
Slovenian: Najnovejše ugotovitve kažejo, da je izpostavljenost pri otrocih, mlajših od 6 let, lahko za približno 30 % manjša od izpostavljenosti pri drugih starostnih skupinah.
English: These haematological effects are not usually observed before four to six weeks therapy.
Slovenian: Ti hematološki učinki se navadno ne pojavijo prej kot po štirih do šestih tednih zdravljenja.
English: However it is not clear whether these cases were due to the antiretroviral treatment or to the underlying HIV disease.
Slovenian: Vendar ni pojasnjeno, če so bili ti primeri posledica protiretrovirusnega zdravljenja ali posledica osnovne HIV bolezni.
English: Tell your doctor if you notice any loss of fat from your legs, arms, and face.
Slovenian: Povejte svojemu zdravniku, če opazite kakršno koli izgubo maščevja na nogah, rokah in obrazu.
English: You may still develop other infections and illnesses linked to HIV infection.
Slovenian: Lahko pa, da se bodo razvile druge okužbe ali bolezni povezane z okužbo s HIV.
English: In vitro susceptibility testing has not been standardised and results may vary according to methodological factors.
Slovenian: Testiranje občutljivosti in vitro ni standardizirano in rezultati se glede na metodološke dejavnike lahko spreminjajo.
English: Depending on the overall condition of the patient, blood tests may be performed less often, for example every one to three months.
Slovenian: Odvisno od splošnega stanja bolnika se lahko krvne preiskave opravljajo tudi redkeje, na primer od enkrat mesečno do enkrat na tri mesece.
English: Drugs by Therapeutic Area Interaction Geometric mean change (%) (Possible mechanism)
Slovenian: Medsebojno delovanje geometrijska sredina spremembe (%) (možni mehanizem)
English: • probenecid, to treat gout and similar conditions, and given with some antibiotics to make them more effective
Slovenian: • probenecid, za zdravljenje putike in podobnih stanj in se ga da skupaj z nekaterimi antibiotiki, da se doseže boljšo učinkovitost;
English: • difficulty in sleeping (insomnia)
Slovenian: • težave s spanjem (insomnija),
English: Consideration should be given to replacing zidovudine in a combination ART regimen if this is already established.
Slovenian: Razmisliti je treba o zamenjavi zidovudina v shemi ART, če je ta že vpeljana.
English: It can be life-threatening, causing failure of internal organs.
Slovenian: Lahko je smrtno nevarna, ker lahko povzroči odpoved notranjih organov.
English: • tiredness, lack of energy
Slovenian: • utrujenost, pomanjkanje energije,
English: Clinical Experience
Slovenian: Klinične izkušnje
English: While the clinical relevance of these findings is unknown, these data suggest that a carcinogenic risk to humans is outweighed by the potential clinical benefit.
Slovenian: Ker klinična pomembnost teh ugotovitev ni znana, ti podatki kažejo na to, da pri človeku potencialna klinična korist prevlada nad tveganjem zaradi karcinogenosti.
English: Zidovudine had a similar effect in both species, but only at very high systemic exposures.
Slovenian: Zidovudin je imel na obe vrsti živali podoben učinek, vendar le pri izredno visoki sistemski izpostavljenosti učinkovini.
English: No special requirements for disposal.
Slovenian: Ni posebnih navodil za odstranjevanje.
English: Take the tablets at regular times, leaving approximately 12 hours between each tablet.
Slovenian: Tablete vzemite ob običajnem času, približno na 12 ur.
English: • if they are also taking anti-inflammatory medicines called corticosteroids
Slovenian: • ki jemljejo tudi protivnetna zdravila imenovana kortikosteroidi;
English: Merckle GmbH Ludwig-Merckle-Strasse 3 89143 Blaubeuren Germany
Slovenian: Merckle GmbH Ludwig-Merckle-Strasse 3 89143 Blaubeuren
English: • serious allergic reaction causing swelling of the face, tongue or throat which may cause difficulty in swallowing or breathing
Slovenian: • resna alergijska reakcija, ki se kaže kot oteklina obraza, jezika ali grla, kar lahko povzroči težave pri požiranju in dihanju,
English: • enlarged breasts in men.
Slovenian: • povečanje prsi pri moških.
English: HIV infection is spread by sexual contact with someone who has the infection, or by transfer of infected blood (for example, by sharing injection needles).
Slovenian: Okužba s HIV se širi s spolnim stikom z okuženo osebo ali s prenosom okužene krvi (npr. s skupno uporabo injekcijskih igel).
English: Additionally, lamivudine has activity against hepatitis B virus (HBV).
Slovenian: Poleg tega lamivudin učinkuje tudi proti virusu hepatitisa B (HBV).
English: Sorbitol solution (3.2g , 10.2 g, 13.4 g)/ Lamivudine
Slovenian: Raztopina sorbitola (3,2g , 10,2 g, 13,4 g)/lamivudin
English: These findings do not affect current national recommendations to use antiretroviral therapy in pregnant women to prevent vertical transmission of HIV.
Slovenian: Te ugotovitve ne vplivajo na trenutna nacionalna priporočila o uporabi protiretrovirusnega zdravljenja pri nosečnicah za preprečitev vertikalnega prenosa okužbe z virusom
English: Pharmacotherapeutic group: Antivirals for treatment of HIV infections, combinations, ATC Code: J05AR01
Slovenian: Farmakoterapevtska skupina: Antivirusna zdravila za zdravljenje HIV, kombinacije; Oznaka ATC: J05AR01
English: • difficulty moving.
Slovenian: • oteženo gibanje.
English: • if you have kidney disease
Slovenian: • če imate bolezen ledvic;
English: In vitro antagonism of anti-HIV activity between stavudine and zidovudine could result in decreased efficacy of both drugs.
Slovenian: In vitro antagonizem anti-HIV aktivnosti med stavudinom in zidovudinom bi lahko povzročil zmanjšano učinkovitost obeh zdravil.
English: Lactic acidosis is a rare but serious side effect
Slovenian: Laktacidoza je redek, vendar resen neželeni učinek
English: Like all medicines, this medicine can cause side effects, but not everybody gets them.
Slovenian: Kot vsa zdravila, ima lahko tudi to zdravilo neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Signs of lactic acidosis include:
Slovenian: Znaki laktacidoze vključujejo:
English: These symptoms are probably caused by the body's immune system becoming stronger, so that the body starts to fight these infections.
Slovenian: Ti simptomi so verjetno posledica okrepitve imunskega sistema in se organizem zopet prične boriti proti tem okužbam.
English: Abbreviations: ↑ = Increase; ↓=decrease; ↔= no significant change; AUC=area under the concentration versus time curve; Cmax=maximum observed concentration; CL/F=apparent oral clearance
Slovenian: Okrajšave: ↑ = povečanje, ↓= zmanjšanje, ↔= ni pomembne spremembe, AUC = površina pod krivuljo koncentracije po času, Cmax = največja opažena koncentracija, CL/F = navidezni peroralni očistek
English: Children who weigh between 14 and 21 kg
Slovenian: Otroci, ki so težki od 14 - 21 kg
English: If you are pregnant, if you become pregnant or if you are planning to become pregnant talk to your doctor about the risks and benefits to you and your baby of taking Lamivudine/Zidovudine Teva.
Slovenian: Če ste noseči, zanosite ali če načrtujete nosečnost, se posvetujte s svojim zdravnikom o tveganjih in koristih jemanja zdravila Lamivudin/zidovudin Teva za vas in vašega otroka.
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant product information for these medicinal products.
Slovenian: V primeru sočasnega protivirusnega zdravljenja hepatitisa B ali C upoštevajte tudi relevantne podatke o teh zdravilih.
English: • vincristine, vinblastine or doxorubicin, to treat cancer.
Slovenian: • vinkristin, vinblastin ali doksorubicin, za zdravljenje raka.
English: In addition, two transplacental carcinogenicity studies have been conducted in mice.
Slovenian: Razen tega so na miših izvedli še dve raziskavi transplacentalne karcinogenosti.
English: - if you are allergic to lamivudine or zidovudine or any of the other ingredients of this medicine (listed in section 6).
Slovenian: - če ste alergični na lamivudin ali zidovudin ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
English: Tell your doctor if you are taking phenytoin.
Slovenian: Zdravniku morate povedati, če jemljete fenitoin.
English: Your doctor will decide if the active substances are suitable for you.
Slovenian: Vaš zdravnik se bo odločil, ali so učinkovine primerne za vas.
English: Date of first authorisation: 02 March 2011 Date of latest renewal: 19 November 2015
Slovenian: Datum zadnjega podaljšanja: 19.11.2015
English: When these people start treatment, they may find that old, hidden infections flare up, causing signs and symptoms of inflammation.
Slovenian: Ko ti bolniki začnejo zdravljenje, se jim lahko razplamtijo stare, prikrite okužbe in povzročijo znake ali simptome vnetja.
English: • if you have ever had liver disease, including hepatitis B or C (if you have hepatitis B infection, do not stop Lamivudine/Zidovudine Teva without your doctor's advice, as your hepatitis may come back)
Slovenian: • če ste kdaj imeli bolezen jeter, vključno s hepatitisom B ali C (če ste okuženi z virusom hepatitisa B, ne prenehajte z jemanjem zdravila Lamivudin/zidovudin Teva brez zdravnikovega navodila, kajti vaš hepatitis se lahko ponovi);
English: Therefore, there is little potential for interactions with antiretroviral protease inhibitors, non-nucleosides and other medicinal products metabolised by major P450 enzymes.
Slovenian: Torej obstaja le majhna možnost za interakcije s protiretrovirusnimi zaviralci proteaz, z nenukleozidi in drugimi zdravili, ki se presnavljajo z glavnimi encimi iz skupine P450.
English: Some medicines can make it more likely that you'll have side effects, or make side effects worse.
Slovenian: Nekatera zdravila lahko povečajo verjetnost, da boste imeli neželene učinke, ali pa da bodo neželeni učinki hujši.
English: The M184V RT mutant shows a <4-fold decrease in susceptibility to didanosine; the clinical significance of these findings is unknown.
Slovenian: Mutant M184V RT kaže < 4-kratno zmanjšanje občutljivosti za didanozin; klinični pomen teh ugotovitev ni znan.
English: Pharmacokinetics in children: In children over the age of 5-6 months, the pharmacokinetic profile of zidovudine is similar to that in adults.
Slovenian: Farmakokinetika pri otrocih: Pri otrocih, starejših od 5-6 mesecev, je farmakokinetični profil zidovudina podoben farmakokinetičnemu profilu pri odraslih.
English: Insufficient data to recommend dosage adjustment.
Slovenian: Za priporočilo o prilagoditvi odmerjanja ni dovolj podatkov.
English: During your treatment, your doctor will monitor you for signs of lactic acidosis.
Slovenian: Med zdravljenjem vas bo vaš zdravnik opazoval glede znakov laktacidoze.
English: Lactic acidosis generally occurred after a few or several months of treatment.
Slovenian: Na splošno se je laktacidoza pojavila že po nekaj ali pa šele po večih mesecih zdravljenja.
English: Lamivudine:
Slovenian: Lamivudin:
English: Lamivudine and zidovudine are well absorbed from the gastrointestinal tract.
Slovenian: Lamivudin in zidovudin se dobro absorbirata iz gastrointestinalnega trakta.
English: You may need extra check-ups, including blood tests, while you are taking your medicine.
Slovenian: Morda boste med jemanjem tega zdravila potrebovali dodatne preglede, vključno s preiskavami krvi.
English: CD4 cells are a type of white blood cells that are important in helping your body to fight infection.
Slovenian: celice so vrsta belih krvnih celic, ki so pomembne za premagovanje okužb.
English: Children who weigh between 21 and 30 kg
Slovenian: Otroci, ki so težki od 21 - 30 kg
English: The second study thus provided no evidence that zidovudine acts as a transplacental carcinogen.
Slovenian: Tako druga raziskava ni pokazala, da bi zidovudin deloval kot transplacentalni karcinogen.
English: Resistance to thymidine analogues (of which zidovudine is one) is well characterised and is conferred by the stepwise accumulation of up to six specific mutations in the HIV reverse transcriptase at codons 41, 67, 70, 210, 215 and 219.
Slovenian: Odpornost na analoge timidina (med katere sodi tudi zidovudin) je nadrobno opisana in se kaže kot postopna akumulacija do šestih specifičnih mutacij reverzne transkriptaze virusa HIV, in sicer na kodonih 41, 67, 70, 210, 215 in 219.
English: Breast-feeding Women who are HIV-positive must not breastfeed, because HIV infection can be passed on to the baby in breast milk.
Slovenian: Ženske, ki so HIV pozitivne, ne smejo dojiti, kajti okužba z virusom HIV se lahko z mlekom prenese na otroka.
English: • hair loss (alopecia).
Slovenian: • izpadanje las (alopecija).
English: • aches and pains (especially in the hip, knee or shoulder)
Slovenian: • bolečine (še posebej v kolku, kolenu ali rami),
English: Each pack type contains 60 film-coated tablets.
Slovenian: Tako ena kot druga vrsta pakiranja vsebujeta po 60 filmsko obloženih tablet.
English: Potential to slightly decrease zidovudine plasma concentrations through UGT induction.
Slovenian: Obstaja možnost za rahlo znižanje plazemske koncetracije zidovudina preko indukcije UGT.
English: Systemic exposures (daily AUC and Cmax) in plasma from the twice daily regimen appeared equivalent to those from the same total daily dose given in three divided doses [Bergshoeff, 2004].
Slovenian: Kaže, da je sistemska plazemska izpostavljenost (dnevni AUC in Cmax) pri režimu odmerjanja dvakrat na dan enaka kot pri uporabi enakega skupnega dnevnega odmerka v obliki treh deljenih odmerkov [Bergshoeff, 2004].
English: • chest pain; disease of the heart muscle (cardiomyopathy)
Slovenian: • bolečina v prsih; bolezen srčne mišice (kardiomiopatija),
English: Zidovudine plasma protein binding is 34 % to 38 %.
Slovenian: Obseg vezave na plazemske proteine znaša pri zidovudinu od 34 do 38 %.
English: Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Slovenian: Preobčutljivost na zdravilno učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1.
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Slovenian: Če opazite kakšne simptome okužbe ali druge simptome, npr. šibkost mišic, šibkost, ki se začne v dlaneh in stopalih in se širi navzgor proti trupu, razbijanje srca (palpitacije), tresenje ali čezmerno aktivnost, o tem takoj obvestite svojega zdravnika, da boste deležni potrebnega zdravljenja.
English: If you have taken Lamivudine/Zidovudine Teva during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Slovenian: Če ste zdravilo Lamivudin/zidovudin Teva jemali med nosečnostjo, vas lahko zdravnik naroči na redne preiskave krvi in druge diagnostične preiskave, da bo spremljal razvoj vašega otroka.
English: • lactic acidosis (excess lactic acid in the blood; see the next section, ‘Other possible side effects of combination therapy for HIV')
Slovenian: • laktacidoza (čezmerno kopičenje mlečne kisline v krvi; glejte poglavje »Drugi možni neželeni učinki kombiniranega zdravljenja okužbe s HIV«),
English: The incidence and severity of lipoatrophy are related to cumulative exposure.
Slovenian: Pojavnost in izrazitost lipoatrofije sta odvisni od kumulativne izpostavljenosti.
English: Due to these differences, the recommended dose for lamivudine in children (aged more than three months and weighing less than 30 kg) is 4 mg/kg twice a day.
Slovenian: Zaradi teh razlik je priporočljivi odmerek lamivudina pri otrocih (starejših od treh mesecev s telesno maso manjšo od 30 kg) 4 mg/kg dvakrat na dan.
English: High doses of trimethoprim/ sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (PCP) and toxoplasmosis have not been studied and should be avoided.
Slovenian: Veliki odmerki trimetoprima/ sulfametoksazola za zdravljenje pljučnice zaradi Pneumocystis jirovecii (PCP) in toksoplazmoze niso raziskani in se jim je treba izogibati.
English: A large amount of data on pregnant women taking lamivudine or zidovudine indicate no malformative toxicity (more than 3000 outcomes from first trimester exposure each of which over 2000 outcomes involved exposure to both lamivudine and zidovudine).
Slovenian: Obsežni podatki o nosečnicah, ki so jemale lamivudin ali zidovudin, niso pokazali malformacijske toksičnosti (za vsakega več kot 3000 izidov po izpostavljenosti v prvem trimesečju, od tega več kot 2000 izidov po izpostavljenosti obema, lamivudinu in zidovudinu).
English: Either of these two patterns of multinucleoside resistance mutations severely limits future therapeutic options.
Slovenian: Oba opisana vzorca mutacij, ki vodita v navzkrižno rezistenco močno omejujeta bodoče terapevtske možnosti.
English: If overdosage occurs the patient should be monitored for evidence of toxicity (see section 4.8), and standard supportive treatment applied as necessary.
Slovenian: V primeru zaužitja prevelikega odmerka je potrebno pri bolniku redno preverjati znake toksičnosti (glejte poglavje 4.8), ter po potrebi pričeti s standardnim podpornim zdravljenjem.
English: In addition, systemic clearance values were greater in younger paediatric patients and decreased with age, approaching adult values around 12 years of age.
Slovenian: Razen tega so pri mlajših otrocih večje tudi vrednosti sistemskega očistka, vendar pa se s starostjo zmanjšujejo in se pri starosti 12 let približajo vrednostim pri odraslih.
English: For patients who are unable to swallow tablets, tablets may be crushed and added to a small amount of semi-solid food or liquid, all of which should be consumed immediately (see section 5.2).
Slovenian: Bolnik, ki tablet ne more pogoltniti, lahko tablete zdrobi in jih doda v manjšo količino redke hrane ali tekočine, ki jo mora nato v celoti takoj zaužiti (glejte poglavje 5.2).
English: Pharmacokinetics in pregnancy: The pharmacokinetics of lamivudine and zidovudine were similar to that of non-pregnant women.
Slovenian: Farmakokinetika med nosečnostjo: Farmakokinetika lamivudina in zidovudina je podobna kot pri ženskah, ki niso noseče.
English: • loss of appetite
Slovenian: • pomanjkanje apetita,
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterium infections, and Pneumocystis jirovecii pneumonia (often referred to as PCP).
Slovenian: Ustrezni primeri so citomegalovirusni retinitis, generalizirane in/ali žariščne okužbe z mikobakterijami in s Pneumocystis jirovecii (pogosto omenjena kot PCP).
English: Blood and lymphatic systems disorders
Slovenian: Bolezni krvi in limfatičnega sistema
English: Lactic acidosis is more likely to develop in people who have liver disease, or in obese (very overweight) people, especially women.
Slovenian: Laktacidoza se bolj verjetno razvije pri ljudeh, ki imajo obolenje jeter, ali pri ljudeh s prekomerno telesno težo, še posebej ženskah.
English: Your doctor should monitor for signs of lipoatrophy.
Slovenian: Zdravnik mora spremljati znake lipoatrofije.
English: For patients with advanced symptomatic HIV disease, it is generally recommended that blood tests are performed at least every two weeks for the first three months of therapy and at least monthly thereafter.
Slovenian: Pri bolnikih z napredovalo simptomatsko HIV boleznijo je priporočljivo, da se krvne preiskave v prvih treh mesecih zdravljenja opravljajo vsaj vsaka dva tedna,
English: It is recommended that mothers infected by HIV do not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Slovenian: Priporočljivo je, da matere, ki so okužene z virosum HIV, v nobenem primeru ne dojijo svojih otrok in se tako izognejo eni od možnosti za prenos virusa HIV na otroka.
English: Data show that lamivudine and zidovudine penetrate the central nervous system (CNS) and reach the cerebrospinal fluid (CSF).
Slovenian: Podatki kažejo, da lamivudin in zidovudin prehajata v centralni živčni sistem (CŽS) in dosežeta cerebrospinalno tekočino (CST).
English: In patients with early HIV disease haematological adverse reactions are infrequent.
Slovenian: Pri bolnikih v zgodnjem obdobju HIV bolezni, so neželene hematološke reakcije redke.
English: Lamivudine and zidovudine are not significantly metabolised by cytochrome P450 enzymes (such as CYP 3A4, CYP 2C9 or CYP 2D6) nor do they inhibit or induce this enzyme system.
Slovenian: Lamivudin in zidovudin se znatneje ne presnavljata s pomočjo encimov iz skupine citokrom P450 (kot so CYP 3A4, CYP 2C9 ali CYP 2D6) omenjenega encimskega sistema tudi ne zavirata ali inducirata.
English: These include:
Slovenian: To so:
English: • an increase in the level of liver enzymes
Slovenian: • povečane vrednosti jetrnih encimov,
English: Very common: Headache
Slovenian: Zelo pogosti: glavobol
English: • if they have been taking combination therapy for a long time
Slovenian: • ki so prejemali kombinirano zdravljenje daljše časovno obdobje;
English: These include: • clarithromycin, an antibiotic if you are taking clarithromycin, take your dose at least 2 hours before or after you take your Lamivudine/Zidovudine Teva.
Slovenian: • antibiotik klaritromicin; Če jemljete klaritromicin, vzemite vaš odmerek vsaj 2 uri pred ali po tem, ko vzamete zdravilo Lamivudin/zidovudin Teva.
English: Patients receiving Lamivudine/Zidovudine Teva should be frequently examined and questioned for signs of lipoatrophy.
Slovenian: Bolnike, ki prejemajo zdravilo Lamivudine/Zidovudine Teva, je treba pogosto pregledovati in vprašati po znakih lipoatrofije.
English: • other medicinal products containing lamivudine, to treat HIV infection or hepatitis B infection
Slovenian: • druga zdravila, ki vsebujejo lamivudin za zdravljenje okužbe s HIV ali hepatitisom B;
English: Monitor for signs of zidovudine toxicity (see section 4.8).
Slovenian: Kontrolirajte glede znakov toksičnosti zidovudina (glejte poglavje 4.8).
English: This dose will achieve an average AUC0-12 ranging from approximately 3,800 to 5,300 ng h/ml.
Slovenian: Takšen odmerek zagotavlja povprečno vrednost AUC0-12 v razponu od približno 3.800 do
English: A subsequent intravaginal carcinogenicity study confirmed the hypothesis that the vaginal tumours were the result of long term local exposure of the rodent vaginal epithelium to high concentrations of unmetabolised zidovudine in urine.
Slovenian: Nadaljnja raziskava intravaginalne karcinogenosti je potrdila hipotezo, da so vaginalni tumorji posledica dolgoročne lokalne izpostavljenosti vaginalnega epitela samic glodavcev visokim koncentracijam nemetaboliziranega zidovudina v urinu.
English: Treatment with zidovudine has been associated with loss of subcutaneous fat which is most evident in the face, limbs and buttocks.
Slovenian: Zdravljenje z zidovudinom je povezano z izgubo podkožnega maščevja, ki je najbolj opazno na obrazu, udih in zadnjici.
English: 3'-amino-3'deoxythymidine (AMT) has been identified as a metabolite of zidovudine following intravenous dosing.
Slovenian: 3'-amino-3'-deoksitimidin (AMT) so identificirali kot presnovek zidovudina, ki se tvori po intravenski aplikaciji.
English: Clinical studies have shown that there are no clinically significant interactions between lamivudine and zidovudine.
Slovenian: S kliničnimi študijami je bilo dokazano, da med lamivudinom in zidovudinom ni klinično pomembnih interakcij.
English: These findings should be considered for any child exposed in utero to nucleoside and nucleotide analogues, who presents with severe clinical findings of unknown etiology particularly neurologic findings.
Slovenian: Te ugotovitve je treba upoštevati pri vseh otrokih, ki so bili in utero izpostavljeni nukleozidnim in nukleotidnim analogom, pri katerih se pojavijo resne klinične ugotovitve neznanega vzroka, še zlasti nevrološke.
English: • feeling depressed or anxious, not being able to concentrate, feeling drowsy
Slovenian: • občutek depresivnosti ali tesnobnosti, nezmožnost koncentracije, občutek dremavosti,