FrancophonIA/ELRC3.0 huggingface dataset:
English: Larger bleeding sites used 1 to 2 grams (10-100 cm²).
Maltese: Siti ikbar ta' ħruġ ta' demm użaw 1 sa 2 grammi (10 - 100 cm²).
English: Hypersensitivity or allergic reactions (which may include angioedema, burning and stinging at the application site, bronchospasm, chills, flushing, generalised urticaria, headache, hives, hypotension, lethargy, nausea, restlessness, tachycardia, tightness of the chest, tingling, vomiting, wheezing) may occur in isolated cases in patients treated with fibrin sealants / haemostatics: these reactions have progressed to severe anaphylaxis.
Maltese: Sensittività eċċessiva jew reazzjonijiet allerġiċi (li jistgħu jinkludu anġjodema, ħruq u tingiż fis-sit talapplikazzjoni, bronkospażmu, tertir ta' bard, fwawar, urtikarja ġeneralizzata, uġigħ ta' ras, ħorriqija, pressjoni baxxa, letarġija, dardir, nuqqas ta' kwiet f'ġismek, takikardija, tagħfis tas-sider, tnemnim, rimettar, tħarħir) jistgħu jseħħu f'każijiet iżolati f'pazjenti ttrattati b'siġillanti tal-fibrin/emostatiċi: dawn ir-reazzjonijiet aggravaw għal anafilassi severa.
English: The safety and efficacy of Raplixa in children and adolescents under the age of 18 years have not been established.
Maltese: Is-sigurtà u l-effikaċja ta' Raplixa fit-tfal u adolexxenti taħt l-età ta' 18-il sena ma ġewx determinati s'issa.
English: Surgery
Maltese: Trehalose
English: Table 1: Required Dose of Raplixa Maximum Surface Area Direct Application from Vial
Maltese: Tabella 1: Doża Meħtieġa ta' Raplixa Erja Massima tal-Wiċċ Applikazzjoni Diretta minn Kunjett
English: As wound healing progresses, increased fibrinolytic activity is induced by plasmin and decomposition of fibrin to fibrin degradation products is initiated.
Maltese: Hekk kif il-fejqan tal-ferita javvanza, tiġi indotta żieda fl-attività fibrinolitika minn plasmin u tinbeda d-dekompożizzjoni ta' fibrin għal prodotti ta' degradazzjoni ta' fibrin.
English: Raplixa sealant powder
Maltese: Raplixa trab siġillant
English: Raplixa may also be used with medical air.
Maltese: Raplixa jista' jintuża wkoll ma' arja medika.
English: • Raplixa will be applied as a thin layer.
Maltese: • Raplixa se jiġi applikat bħala saff irqiq.
English: Pharmacotherapeutic group: local haemostatics, other haemostatics ATC code: B02BC30
Maltese: Kategorija farmakoterapewtika: emostatiċi lokali, emostatiċi oħrajn Kodiċi ATC:
English: As a consequence, intravascular pharmacokinetic studies were not performed in man. Fibrin Sealants/haemostatics are metabolised in the same way as endogenous fibrin by fibrinolysis and phagocytosis.
Maltese: Siġillanti tal-Fibrin/emostatiċi jiġu mmetabolizzati bl-istess mod bħal fibrina endoġenu permezz ta' fibrinoliżi u fagoċitożi.
English: The measures may be of limited value against non- enveloped viruses such as HAV and parvovirus B19.
Maltese: Il-miżuri jistgħu jkunu ta' valur limitat kontra viruses li mhumiex enveloped bħal HAV u parvovirus B19.
English: Recommended distance from target tissue
Maltese: Distanza rakkomandata mill-tessut filmira
English: Raplixa may also be used with medical air (see sections 4.4 and 6.6).
Maltese: Raplixa jista' jintuża wkoll ma' arja medika (ara sezzjonijiet 4.4 u 6.6).
English: In clinical trials, smaller bleeding sites (< 10 cm²) used 0.5 g to 1 g on average.
Maltese: Fil-provi kliniċi, siti iżgħar ta' ħruġ ta' demm (<10 cm²) użaw 0.5 g sa 1 g bħala medja.
English: Conversion of fibrinogen into fibrin occurs by the splitting of fibrinogen into fibrin monomers and fibrinopeptides.
Maltese: Ilkonverżjoni ta' fibrinogen għal fibrin isseħħ permezz tal-qsim ta' fibrinoġen f'monomers tal-fibrin u fibrinopeptides.
English: - directly inside a blood vessel - in endoscopic procedures (procedures that use an endoscope for viewing internal organs) or keyhole surgery
Maltese: - direttament ġo vina/arterja - fi proċeduri endoskopiċi (proċeduri li jużaw endoskopju biex wieħed jara l-organi interni) jew
English: Known hypersensitivity to the Raplixa active substances or to any of the excipients listed in section 6.1.
Maltese: Sensittività eċċessiva għas-sustanzi attivi ta' Raplixa jew għal kwalunkwe wieћed mill-eċċipjenti elenkati fis-sezzjoni 6.1.
English: Standard measures to prevent infections resulting from the use of medicinal products prepared from human blood or plasma include selection of donors, screening of individual donations and plasma pools for specific markers of infection and the inclusion of effective manufacturing steps for the inactivation/removal of viruses.
Maltese: Miżuri standard biex jiġu evitati infezzjonijiet li jirriżultaw mill-użu ta' prodotti mediċinali ppreparati minn demm jew plażma umana jinkludu l-għażla tad-donaturi, screening ta' donazzjonijiet individwali u pools ta' plażma għal markaturi speċifiċi ta' infezzjoni u l-inklużjoni ta' passi effettivi talmanifattura għall-inattivazzjoni/tneħħija ta' viruses.
English: Not relevant.
Maltese: Mhux rilevanti
English: Each gram of powder contains 79 mg human fibrinogen and 726 IU human thrombin.
Maltese: Kull gramma ta' trab fiha 79 mg ta' fibrinogen uman u 726 IU ta' thrombin uman.
English: Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard
Maltese: Tista' wkoll tirrapporta effetti sekondarji direttament permezz ADR Reporting, Website: www.medicinesauthority.gov.mt/adrportal.
English: In clinical trials a thin layer of Raplixa produced doses that typically ranged from 0.3 to 2 g. For some procedures eg.
Maltese: Fil-provi kliniċi, saff irqiq ta' Raplixa pproduċa dożi li tipikament varjaw minn 0.3 sa 2 g.
English: Prior to launch of Raplixa in each Member State the Marketing Authorisation Holder (MAH) must agree about the content and format of the educational programme, including communication media, distribution modalities, and any other aspects of the programme, with the National Competent Authority.
Maltese: Qabel it-tnedija ta' Raplixa f'kull Stat Membru, id-Detentur tal-Awtorizzazzjoni għat-Tqegħid fis-Suq (MAH) irid jaqbel dwar il-kontenut u l-format tal-programm edukattiv, li jinkludi media talkomunikazzjoni, modalitajiet ta' distribuzzjoni, u kwalunkwe aspetti oħra tal-programm, mal-Awtorità Kompetenti Nazzjonali.
English: Fibrin sealants may, in rare cases (up to 1 in 1,000 people), cause an allergic reaction.
Maltese: Siġillanti tal-fibrin jistgħu, f'każijiet rari (sa 1 minn kull 1000 persuna), jikkawżaw reazzjoni allerġika.
English: There is also a possibility that you could develop antibodies to the proteins in Raplixa, which could potentially interfere with blood clotting.
Maltese: Hemm ukoll possibbiltà li inti tista' tiżviluppa antikorpi għall-proteini li hemm f'Raplixa, li potenzjalment jistgħu jinterferixxu mat-tagħqid tad-demm.
English: When spraying Raplixa, safety will be monitored because of the possibility of occurrence of air or gas embolism.
Maltese: Meta tisprejja Raplixa, is-sigurtà se tiġi mmonitorjata minħabba l-possibbiltà ta' okkorrenza ta' emboliżmu tal-arja jew tal-gass.
English: Raplixa must not be applied intravascularly.
Maltese: Raplixa ma jridx jiġi applikat b'mod intravaskulari.
English: Direct application followed by gelatin sponge
Maltese: Applikazzjoni diretta segwita minn sponża tal-ġelatina
English: The measures taken in the manufacture of fibrinogen and thrombin are considered effective for lipid coated viruses such as HIV (human immunodeficiency virus), hepatitis B virus and hepatitis C virus.
Maltese: Il-miżuri li jittieħdu fil-manifattura ta' fibrinogen u thrombin huma kkunsidrati li huma effettivi għal viruses miksija bil-lipidi bħal HIV (virus tal-immunodefiċjenza umana), il-virus tal-epatite B u l-virus tal-epatite Ċ.
English: When applying Raplixa using the Raplixa spray device, the pressure should be within the range recommended by ProFibrix.
Maltese: Meta tapplika Raplixa billi tuża t-tagħmir RaplixaSpray, il-pressjoni għandha tkun fil-medda rakkomandata minn ProFibrix.
English: The Raplixa should be stored at controlled, ambient room temperature.
Maltese: Raplixa għandu jinħażen f'temperatura kkontrollata u ambjentali tal-kamra.
English: There are three methods of application: direct application of Raplixa to the bleeding tissue followed by application of the gelatin sponge or application of Raplixa first to a gelatin sponge and application of the sponge to the bleeding tissue; or application of the Raplixa powder by using the RaplixaSpray device followed by the application of the gelatin sponge.
Maltese: Hemm 3 metodi ta' applikazzjoni: applikazzjoni diretta ta' Raplixa fuq it-tessut fejn ikun hemm ilħruġ ta' demm segwita minn applikazzjoni tal-isponża tal-ġelatina, jew l-applikazzjoni ta' Raplixa lewwel fuq sponża tal-ġelatina u l-applikazzjoni tal-isponża tal-ġelatina fuq it-tessut fejn ikun hemm ilħruġ ta' demm; jew l-applikazzjoni ta' Raplixa trab billi tuża t-tagħmir RaplixaSpray segwita millapplikazzjoni tal-isponża tal-ġelatina.
English: Active
Maltese: Attiv
English: Raplixa may be denatured after exposure to solutions containing alcohol, iodine or heavy metals (e.g. antiseptic solutions).
Maltese: Raplixa jista' jiġi denaturat wara esponiment għal soluzzjonijiet li fihom l-alkoħol, jodju jew heavy metals (eż. soluzzjonijiet antisettiċi).
English: Parvovirus B19 infection may be serious for pregnant women (foetal infection) and for individuals whose immune system is depressed or who have some types of anaemia (for example sickle cell disease or haemolytic anaemia).
Maltese: Infezzjoni b'parvovirus B19 tista' tkun serja għal nisa tqal (infezzjoni fetali) u għal individwi li s-sistema immuni tagħhom tkun baxxa jew li jkollhom xi tipi ta' anemija (per eżempju, il-marda taċ-ċelluli sickle jew anemija).
English: instructions for use
Maltese: Użu u applikazzjoni
English: The Raplixa spray device is connected to the RaplixaReg pressure regulator and thereby to the medical gas supply set to a pressure setting of 1.5 bar (22 psi).
Maltese: Raplixa jista' jintuża wkoll ma' arja ta' grad mediku) issettjat fuq setting ta' pressjoni ta' 1.5 bar (22 psi).
English: Raplixa is a pre-mixed, ready to use blend of thrombin and fibrinogen supplied as a ready to use drypowder fibrin sealant in a glass vial containing 0.5 g, 1 g or 2 g of Raplixa that is applied onto the surgical bleeding site directly from the vial or using the RaplixaSpray device.
Maltese: Raplixa hu taħlita mħallta minn qabel, lesta biex tintuża, ta' thrombin u fibrinogen, fornuti bħala trab xott ta' siġillant tal-fibrin, lesti biex jintużaw, f'kunjett tal-ħġieġ li jkun fih 0.5, 1 g jew 2 g ta' Raplixa, li jiġi applikat fuq is-sit tal-ħruġ ta' demm kirurġiku direttament mill-kunjett jew bl-użu tattagħmir RaplixaSpray.
English: If you experience an allergic reaction you might have one or more of the following symptoms: skin rash, hives or wheals (nettle-rash), tightness of the chest, chills, flushing, headache, low blood pressure, lethargy, nausea, restlessness, increased heart rate, tingling, vomiting or wheezing.
Maltese: Jekk ikollok reazzjoni allerġika, jista' jkollok wieħed jew aktar mis-sintomi li ġejjin: raxx tal-ġilda, ħorriqija jew irqajja' ħomor imqabbża ‘l fuq (raxx tal-ħurrieq), tagħfis tas-sider, tertir ta' bard, fwawar, uġigħ ta' ras, pressjoni tad-demm baxxa, letarġija, dardir, nuqqas ta' sabar, żieda fir-rata ta' taħbit talqalb, tnemnim, rimettar jew tħarħir.
English: Raplixa is applied during surgical operations, to reduce bleeding and oozing during and after the operation in adults.
Maltese: Raplixa jiġi applikat matul operazzjonijiet kirurġiċi, biex inaqqas il-ħruġ ta' demm u t-tnixxija matul u wara l-operazzjoni fl-adulti.
English: HPRA Pharmacovigilance Earlsfort Terrace IRL - Dublin 2
Maltese: 5.3 Tagħrif ta' qabel l-użu kliniku dwar is-sigurtà
English: Connect the RaplixaSpray device to the RaplixaReg air pressure regulator or CO2 pressure regulator and thereby to the medical air or CO2 gas supply set to a pressure setting of 1.5 bar (22 psi).
Maltese: Qabbad it-tagħmir ta' RaplixaSpray mar-regolatur tal-pressjoni tal-arja RaplixaReg jew mar-regolatur tal-pressjoni CO2 u mbagħad mal-arja medika jew mal-provvista tal-gass CO2 issettjata fuq setting ta' pressjoni ta' 1.5 bar (22 psi).
English: • Official batch release
Maltese: • Diffikultà biex torqod
English: The safety of Raplixa for use in human pregnancy or during breast-feeding has not been established in controlled clinical trials.
Maltese: Is-sigurtà ta' Raplixa għall-użu fit-tqala umana jew matul it-treddigħ ma ġietx stabbilita fil-provi kliniċi kkontrollati.
English: Prior to applying Raplixa the surface area of the wound needs to be dried by standard techniques (e.g. intermittent application of compresses, swabs, use of suction devices).
Maltese: Qabel ma jiġi applikat Raplixa, l-erja tal-wiċċ tal-ferita jeħtieġ li titnixxef permezz ta' tekniki standard (eż. l-applikazzjoni intermittenti ta' kompressi, swabs, l-użu ta' tagħmir tal-ġbid).
English: The following side effects have also been reported: Common side effects (may affect up to 1 in 10 people):
Maltese: Effetti sekondarji komuni (jistgħu jaffettwaw sa 1 minn kull 10 persuni):
English: Tabulated list of adverse reactions
Maltese: Lista tabulata ta' reazzjonijiet avversi Sistema tal-klassifika tal-organi
English: For safety with respect to transmissible agents, see section 4.4.
Maltese: Għas-sigurtà fir-rigward ta' aġenti trasmissibbli, ara sezzjoni 4.4
English: For instructions on use of the medicinal product before administration, see section 6.6.
Maltese: Għal struzzjonijiet fuq l-użu tal-prodott mediċinali qabel l-amministrazzjoni, ara sezzjoni 6.6.
English: The measures taken may be of limited value against non-enveloped viruses as hepatitis A virus and parvovirus B19 (causing fifth disease).
Maltese: Il-miżuri li jittieħdu jistgħu jkunu ta' valur limitat kontra viruses li mhumiex enveloped bħall-virus tal-epatite A u parvovirus B19 (li jikkawża l-ħames marda).
English: Parvovirus B19 may be serious for pregnant women (fetal infection) and of individuals with immunodeficiency or increased erythropoiesis (e.g. Haemolytic anaemia).
Maltese: B19 jista' jkun serju għal nisa tqal (infezzjoni fetali) u għal individwi b'immunodefiċjenza jew żieda f'eritropojeżi (eż. Anemija emolitika).
English: • Use preferred pressurised CO2 instead of pressurised air
Maltese: • L-użu ppreferut ta' CO2 taħt pressa minflok arja taħt pressa
English: Spray application using Raplixa spray device followed by gelatin sponge Use Raplixa with the Raplixa spray device.
Maltese: Applikazzjoni tal-isprej bl-użu tat-tagħmir RaplixaSpray segwita minn sponża tal-ġelatina Uża Raplixa bit-tagħmir RaplixaSpray.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with Raplixa in one or more subsets of the paediatric population in the treatment of haemorrhage resulting from surgical procedure as per Paediatric Investigational Plan (PIP) decision, for the granted indication (see section 4.2 for information on paediatric use).
Maltese: L-Aġenzija Ewropea għall-Mediċini iddifferiet l-obbligu li jiġu ppreżentati riżultati tal-istudji b'Raplixa f'wieħed jew iktar settijiet tal-popolazzjoni pedjatrika fit-trattament ta' emorraġija li tirriżulta minn proċedura kirurġika kif imniżżel fid-deċiżjoni tal-Pjan ta' Implimentazzjoni Pedjatrika (PIP), għal indikazzjoni mogħtija (ara sezzjoni 4.2 għal informazzjoni dwar l-użu pedjatriku).
English: Children and adolescents Raplixa has not been evaluated for safety and effectiveness in children.
Maltese: Tfal u adolexxenti Raplixa ma ġiex evalwat għas-sigurtà u l-effettività fit-tfal.
English: The surgeon treating you will administer Raplixa during surgery.
Maltese: L-użu ta Raplixa hu ristrett għal kirurgi b'esperjenza.
English: Apply first to gelatin sponge
Maltese: Applika l-ewwel fuq sponża tal-ġelatina
English: The active ingredient fibrinogen is a concentrate of clottable protein; the other active ingredient thrombin is an enzyme that causes clottable protein to coalesce to form a plug.
Maltese: Is-sustanza attiva fibrinogen hi konċentrat ta' proteina li tista' tagħqad; is-sustanza attiva l-oħra, thrombin, hi enzima li tikkawża proteina li tista' tagħqad, biex tagħqad u tifforma qoxra.
English: Do not use Raplixa (and gelatin sponge) in contaminated areas of the body, or in the presence of active infection.
Maltese: Tużax Raplixa (u l-isponża tal-ġelatina) f'żoni kontaminati tal-ġisem, jew fil-preżenza ta' infezzjoni attiva.
English: sealant powder
Maltese: Trab siġillant
English: Raplixa is a pre-mixed, blend of thrombin and fibrinogen supplied as a ready to use dry-powder fibrin sealant in a glass vial containing 0.5 g, 1 g or 2 g of Raplixa.
Maltese: Raplixa hu trab abjad xott, lest biex jintuża, imħallat minn qabel, fornut f'kunjett li fih jew 0.5 g, 1 g, jew 2 g.
English: Connect the RaplixaSpray device to the RaplixaReg pressure regulator and thereby to the medical CO2 gas supply (CO2 is recommended; Raplixa may be also used with medical grade air) set to a pressure setting of 1.5 bar (22 psi).
Maltese: Ikkonnettja t-tagħmir ta' RaplixaSpray mar-regolatur tal-pressjoni RaplixaReg u mbagħad malprovvista tal-gass CO2 mediku (CO2 hu rakkomandat;
English: To avoid the risk of potentially life-threatening air embolism, it is recommended that Raplixa should be sprayed using pressurised CO2.
Maltese: Biex tevita r-riskju ta' emboliżmu ta' arja potenzjalment ta' theddida għall-ħajja, hu rakkomandat li Raplixa jiġi sprejjat billi tuża CO2 taħt pressa.
English: Do not use Raplixa:
Maltese: Sustanzi mhux attivi:
English: Calcium ions are required for both, the conversion of fibrinogen and the crosslinkage of fibrin.
Maltese: Joni tal-calcium huma meħtieġa kemm għall-konverżjoni ta' fibrinogen kif ukoll għall-crosslinkage ta' fibrin.
English: The combination of Raplixa and a gelatin sponge reduced the median time to haemostasis at target sites by up to 2 minutes compared to a gelatin sponge alone.
Maltese: Il-kombinazzjoni ta' Raplixa u sponża tal-ġelatina naqqsu l-ħin medjan għall-emostasi fis-siti fil-mira b'massimu ta' 2 minuti meta mqabbla ma' sponża tal-ġelatina waħidha.
English: Raplixa must not be used as a glue for intestines (gastrointestinal anastomoses).
Maltese: Raplixa ma jridx jintuża bħala kolla għall-imsaren (anastomożijiet gastrointestinali).
English: Fertility Fertility studies have not been conducted.
Maltese: Fertilità Ma sarux studji fuq il-fertilità.
English: Air or gas emboli
Maltese: TAS-SUSTANZA BIJOLOĠIKA ATTIVA U
English: Fax: +353 1 6762517 Website: www.hpra.ie e-mail: medsafety@hpra.ie
Maltese: Il-professjonisti dwar il-kura tas-saħħa huma mitluba jirrappurtaw kwalunkwe reazzjoni avversa suspettata permezz ADR Reporting, Website: www.medicinesauthority.gov.mt/adrportal.
English: The RaplixaSpray device comes with the rigid nozzle attached, which can be easily removed and the flexible nozzle attached depending on the intended use and surgeon preference.
Maltese: Din tista' titneħħa u n-nozzle flessibbli tista' titwaħħal skont l-użu intenzjonat u l-preferenza tal-kirurgu.
English: • When Raplixa is applied during surgery, the surgeon must ensure that it is only applied onto the surface of tissue.
Maltese: • Meta Raplixa jiġi applikat waqt operazzjoni, il-kirurgu jrid jiżgura li Raplixa jiġi applikat biss fuq il-wiċċ tat-tessut.
English: Spray application using RaplixaSpray device followed by gelatin sponge The vial and RaplixaSpray device are taken out of their respective pouches maintaining sterility.
Maltese: Minkejja dan, meta jingħataw prodotti mediċinali ppreparati minn demm jew plażma umana, il-possibbiltà li jiġu trasmessi aġenti infettivi ma tistax tiġi eskluża totalment.
English: In absence of compatibility studies, Raplixa must not be mixed with other medicinal products.
Maltese: Fin-nuqqas ta' studji ta' kompatibbiltà, Raplixa m'għandux jitħallat ma' prodotti mediċinali oħrajn.
English: The MAH shall ensure that in each Member State where Raplixa is marketed, all healthcare professionals who are expected to use Raplixa are provided with the following educational material:
Maltese: L-MAH għandu jiżgura li f'kull Stat Membru fejn Raplixa jkun fis-suq, il-professjonisti kollha filqasam mediku li huma mistennija li jużaw Raplixa, jiġu pprovduti bil-materjal edukattiv li ġej:
English: Supportive treatment where standard surgical techniques are insufficient for improvement of haemostasis.
Maltese: Trattament ta' appoġġ fejn tekniki kirurġiċi standard ma jkunux biżżejjed għat-titjib tal-emostasi.
English: Raplixa has been studied in patients undergoing spinal surgery, vascular surgery, soft tissue surgery and hepatic resection.
Maltese: Raplixa ġie studjat f'pazjenti li kienu qed jagħmlu operazzjoni tas-sinsla, operazzjoni vaskulari, operazzjoni tat-tessut artab u risezzjoni tal-fwied.
English: Target amount Quantity
Maltese: U KWANTITATTIVA
English: See the end of Section 4 for how to report side effects.
Maltese: Ara t-tmiem ta' sezzjoni 4 biex tara kif għandek tirrapporta effetti sekondarji.
English: There is limited experience of use of Raplixa in vascular surgery when applied with the RaplixaSpray device.
Maltese: Hemm esperjenza limitata tal-użu ta' Raplixa f'operazzjoni vaskulari meta applikat bit-tagħmir ta' RaplixaSpray.
English: When applying Raplixa using a spray device, a defined pressure within the range recommended by the spray device manufacturer is to be used.
Maltese: KONDIZZJONIJIET JEW RESTRIZZJONIJIET FIR-RIGWARD TALUŻU SIGUR U EFFIKAĊI TAL-PRODOTT MEDIĊINALI
English: Bleeding at target sites was mild or moderate.
Maltese: Il-ħruġ ta' demm fissiti fil-mira kien ħafif jew moderat.
English: ATTENTION:
Maltese: ATTENZJONI:
English: Elderly patients (≥65 years)
Maltese: Pazjenti adulti (≥65 sena)
English: Demographics
Maltese: Demografiċi
English: Somatostatin (SRIF-14)
Maltese: Somatostatin (SRIF-14) Pasireotide
English: N=65 n (%), p value
Maltese: N=65 n (%), valur p
English: • insulin;
Maltese: • insulina;
English: Date of first authorisation: 24 April 2012 Date of latest renewal: 18 November 2016
Maltese: Data tal-aħħar tiġdid: 18 Novembru 2016
English: ULN = upper limit of normal
Maltese: ULN = l-ogħla limitu tan-normal
English: Normalisation of IGF-1
Maltese: Normalizzazzjoni ta' IGF-1
English: Bradycardic medicinal products
Maltese: Prodotti mediċinali bradikardijaċi
English: Severe hepatic impairment (Child Pugh C).
Maltese: Indeboliment gravi tal-fwied (Child Pugh C).
English: Adrenal insufficiency*
Maltese: Insuffiċjenza adrenali*
English: 6 ampoules
Maltese: 6 ampulli
English: • insulin
Maltese: • insulina
English: • beta blockers (metoprolol, carteolol, propranolol, sotalol)
Maltese: • imblukkaturi beta (metoprolol, carteolol, propranolol, sotalol)
English: Solvent for Signifor
Maltese: Solvent għal Signifor
English: - Problems with bile flow (cholestasis).
Maltese: - Problemi bil-fluss tal-bili (kolestażi).
English: Five human somatostatin receptor subtypes are known: hsst1, 2, 3, 4, and 5.
Maltese: riċetturi umani ta' somatostatin: hsst1, 2, 3, 4, u 5.
English: A total of 358 patients were randomised and treated.
Maltese: Total ta' 358 pazjent kienu randomizzati u kkurati.
English: • calcium channel blockers (bepridil, verapamil, diltiazem)
Maltese: • imblukkaturi tal-kanal tal-kalċju (bepridil, verapamil, diltiazem)
English: Octreotide intramuscular use n (%) N=182
Maltese: Octreotide użu għal ġol-muskoli n (%) N=182
English: Pancreatic enzymes
Maltese: Enzimi pankreatiċi
English: What Signifor contains - The active substance is pasireotide.
Maltese: X'fih Signifor - Is-sustanza attiva hi pasireotide.
English: Table 2 Binding affinities of somatostatin (SRIF-14), pasireotide, octreotide and lanreotide to the five human somatostatin receptor subtypes (hsst1-5)
Maltese: Tabella 2 Affinitajiet ta' twaħħil ta' somatostatin (SRIF-14), pasireotide, octreotide u lanreotide mal-ħames sottotipi ta' riċetturi somatostatin (hsst1-5)
English: The study enrolled 150 patients.
Maltese: L-istudju kien jinkludi 150 pazjent.
English: Insulin and antidiabetic medicinal products
Maltese: Insulina u prodotti mediċinali antidijabetiċi
English: • metformin, liraglutide, vildagliptin, nateglinide (antidiabetic medicines).
Maltese: • metformin, liraglutide, vildagliptin, nateglinide (mediċini antidijabetiċi).
English: - Signifor controls over-production of cortisol.
Maltese: - Signifor jikkontrolla l-produzzjoni eċċessiva ta' kortisol.