FrancophonIA/ELRC3.0 huggingface dataset:
English: If you are receiving dialysis treatment when you begin treatment with Silapo, your dialysis regimen may need to be adjusted to maintain urea, creatinine and potassium levels in the desired range.
Slovenian: Če ste ob začetku zdravljenja z zdravilom Silapo na dializi, bo mogoče treba popraviti vaš urnik na dializi, da sečnina, kreatinin in kalij ostanejo v želenih mejah.
English: However, if the haemoglobin has increased < 1 g/dl (< 0.62 mmol/l) and the reticulocyte count has increased < 40 000 cells/µl above baseline, response is unlikely and treatment should be discontinued.
Slovenian: Če pa se je hemoglobina zvišal <1 g/dl (0,62 mmol/l) ali če se je število retikulocitov dvignilo <40 000 celic/µl nad osnovno vrednost, odziva verjetno ni in je treba zdravljenje prekiniti.
English: The clinical data available suggest that those patients whose initial haemoglobin is very low (< 6 g/dl or < 3.75 mmol/l) may require higher maintenance doses than those whose initial anaemia is less severe (Hb > 8 g/dl or > 5 mmol/l).
Slovenian: Klinični podatki, ki so na razpolago kažejo, da so za bolnike z zelo nizkim začetnim nivojem hemoglobina (< 6 g/dl ali < 3,75 mmol/l) lahko potrebni višji vzdrževalni odmerki kot v primeru manj hude začetne anemije (Hb > 8 g/dl ali > 5 mmol/l).
English: Correction phase: Starting dose of 50 IU/kg 2 times per week.
Slovenian: Korekcijska faza: začetni odmerek 50 i.e./kg dvakrat tedensko.
English: All patients being treated with Silapo should receive adequate iron supplementation (e.g. 200 mg oral elemental iron daily) throughout the course of treatment.
Slovenian: Vsem bolnikom, ki dobivajo zdravilo Silapo, je treba ves čas zdravljenja dodajati ustrezen dodatek z železom (npr. 200 mg elementarnega železa peroralno na dan).
English: Treatment of patients with chemotherapy induced anaemia
Slovenian: Zdravljenje bolnikov, pri katerih je anemijo povzročila kemoterapija
English: If haemoglobin level exceeds 12 g/dl (7.5 mmol/l), discontinue therapy until it falls to 12 g/dl (7.5 mmol/l) or lower and then reinstitute Silapo therapy at a dose 25% below the previous dose.
Slovenian: Če je koncentracija hemoglobina nad 12 g/dl (7,5 mmol/l), zdravljenje prekinemo, dokler ne pade na 12 g/dl (7,5 mmol/l) ali nižje, potem pa nadaljujemo s terapijo z zdravilom Silapo z odmerkom, ki je 25 % nižji od predhodnega.
English: Each pack contains 1 or 6 pre-filled syringes.
Slovenian: Vsako pakiranje vsebuje 1 do 6 vnaprej napolnjenih brizg.
English: In cases where there is a medical need to shorten the lead time before surgery to less than three weeks, 300 IU/kg should be administered subcutaneously daily for 10 consecutive days prior to surgery, on the day of surgery and for four days immediately thereafter.
Slovenian: Če je treba zaradi zdravstvenih razlogov skrajšati čas pred kirurškim posegom na manj kot tri tedne, je treba dajati odmerek 300 i.e./kg telesne mase na dan, in sicer 10 dni zapored pred kirurškim posegom, na dan kirurškega posega in še štiri dni takoj po njem.
English: Each pack contains 1 or 4 pre-filled syringes.
Slovenian: Vsako pakiranje vsebuje 1 do 4 vnaprej napolnjenih brizg.
English: Therefore, epoetin zeta should not be used in patients with baseline haemoglobin > 13 g/dl.
Slovenian: Zato se epoetina zeta pri bolnikih z izhodiščno koncentracijo hemoglobina > 13 g/dl ne sme uporabljati.
English: The dose should remain the same while the change is being made.
Slovenian: Med menjavo se odmerka ne spreminja.
English: Chronic renal failure patients on erythropoietin should have their haemoglobin levels measured on a regular basis until a stable level is achieved, and periodically thereafter to minimise the risk of an increase in blood pressure.
Slovenian: Bolnikom s kronično ledvično okvaro, ki dobivajo eritropoetin, morajo redno meriti nivo hemoglobina tako dolgo, da se koncentracija ustali, potem pa v enakih časovnih intervalih, da se zmanjša nevarnost zvišanja krvnega tlaka.
English: Dose adjustment
Slovenian: Prilagajanje odmerka
English: Adult surgery patients in an autologous predonation programme
Slovenian: Odrasli kirurški bolniki v programu darovanja avtologne krvi
English: There may be a rise in the level of platelets (cells that help blood clotting) during treatment with this medicine.
Slovenian: Med zdravljenjem s tem zdravilom lahko pride do porasta v številu trombocitov (celic, ki pomagajo pri strjevanju krvi).
English: Adult and paediatric haemodialysis patients, adult peritoneal dialysis patients and adult patients with renal insufficiency not yet undergoing dialysis
Slovenian: Odrasli in otroci, ki se zdravijo s hemodializo, odrasli bolniki, ki se zdravijo s peritonealno dializo, in odrasli bolniki z ledvično insuficienco, ki se še ne zdravijo z dializo
English: Hypertension may occur in epoetin alfa treated patients.
Slovenian: Pri bolnikih, ki se zdravijo z epoetinom alfa, se lahko pojavi hipertenzija.
English: Alternatively, your doctor may recommend a starting dose of 450 IU/kg once a week.
Slovenian: Zdravnik lahko priporoči tudi začetni odmerek 450 i.e./kg enkrat tedensko.
English: • Arm or leg pain
Slovenian: • Bolečine v rokah ali nogah.
English: - The other ingredients are disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, sodium chloride, calcium chloride dihydrate, polysorbate 20, glycine, leucine, isoleucine, threonine, glutamic acid, phenylalanine, water for injections, sodium hydroxide (pH adjuster), hydrochloric acid (pH adjuster).
Slovenian: Druge sestavine zdravila so dinatrijev fosfat dihidrat, natrijev dihidrogen fosfat dihidrat, natrijev klorid, kalcijev klorid dihidrat, polisorbat 20, glicin, levcin, izolevcin, treonin, glutamatna kislina, fenilalanin, voda za injekcije, natrijev hidroksid (za prilagoditev pH), klorovodikova kislina (za prilagoditev pH).
English: in adult patients on peritoneal dialysis to treat symptomatic anaemia associated with chronic renal failure (kidney disease).
Slovenian: pri odraslih na peritonealni dializi, kot zdravilo za simptomatsko anemijo v zvezi s kronično ledvično okvaro(bolezen ledvic).
English: If the rate of increase in haemoglobin exceeds 2 g/dl (1.25 mmol/l) per month or the haemoglobin level exceeds 12 g/dl (7.5 mmol/l), the dose adjustment detailed in section 4.2 should be thoroughly performed to minimise the risk of thrombotic events (see section 4.2).
Slovenian: Če hitrost naraščanja hemoglobina presega 2 g/dl (1,25 mmol/l) na mesec ali če nivo hemoglobina presega 12 g/dl (7,5 mmol/l), je potrebno opraviti korenito spremembo odmerka, kot je navedeno v poglavju 4.2, da bi se zmanjšalo riziko tveganja za trombotične zaplete (glejte poglavje 4.2)
English: Your doctor should try to keep your haemoglobin levels between 10 and 12g/dl.
Slovenian: Vaš zdravnik mora poskušati obdržati raven vašega hemoglobina med 10 in 12g/dl.
English: Includes arterial and venous, fatal and non fatal events, such as deep venous thrombosis, pulmonary emboli, retinal thrombosis, arterial thrombosis (including myocardial infarction), cerebrovascular accidents (including cerebral infarction and cerebral haemorrhage) transient ischaemic attacks, and shunt thrombosis (including dialysis equipment) and thrombosis within arteriovenous shunt aneurisms Addressed in the subsection below and/or in section 4.4
Slovenian: Vključuje arterijske in venske dogodke, s smrtnim izidom in brez njega, kot so globoka venska tromboza, pljučna embolija, tromboza mrežnice, arterijska tromboza (vključno z miokardnim infarktom), cerebrovaskularne dogodke (vključno s cerebralnim infarktom in cerebralno krvavitvijo), prehodne ishemične napade in trombozo šanta (vključno z dializno opremo) in trombozo v arteriovenskih anevrizmah šanta.
English: The recommended starting dose is 150 IU/kg.
Slovenian: Priporočeni začetni odmerek je 150 i.e./kg.
English: PRCA means the inability to produce enough red blood cells in the bone marrow.
Slovenian: PRCA pomeni, da v kostnem mozgu ne nastaja zadostno število rdečih krvnih celic.
English: Early shunt revision and thrombosis prophylaxis by administration of acetylsalicylic acid, for example, is recommended in these patients.
Slovenian: Pri teh bolnikih je priporočena zgodnja revizija šanta in antiagregacijska profilaksa z uporabo acetilsalicilne kisline.
English: You may have chest pain, breathlessness, and painful swelling and redness, usually in the leg as symptoms.
Slovenian: Morda se vam kot simptomi pojavijo bolečine v prsih, zasoplost in boleče otekanje in rdečina, običajno nog.
English: Silapo 8 000 IU
Slovenian: Silapo 8 000 i.e.
English: It may be necessary to add or increase anti-hypertensive treatment.
Slovenian: Morda bo potrebno zvišati ali dodati odmerek zdravila za zdravljenje visokega krvnega tlaka.
English: Adult patients with renal insufficiency not yet undergoing dialysis
Slovenian: Odrasli bolniki z ledvično insuficienco, ki se še ne zdravijo z dializo
English: Use in adults scheduled for major orthopaedic surgery
Slovenian: Uporaba pri odraslih, naročenih na večji ortopedski kirurški poseg
English: • shortened overall survival and increased deaths attributed to disease progression at 4 months in patients with metastatic breast cancer receiving chemotherapy when administered to target a haemoglobin of 12-14 g/dl (7.5 -8.7 mmol/l),
Slovenian: • skrajšanega časa skupnega preživetja in povečanja števila smrti, ki jih pripisujejo napredovanju bolezni po 4 mesecih pri bolnikih z metastaznim rakom dojk na kemoterapiji, pri katerih so z uporabo sredstev za stimulacijo eritropoeze želeli doseči ciljne koncentracije hemoglobina od 12-14 g/dl (7,5-8,7 mmol/l),
English: One pack contains 1, 4 or 6 pre-filled syringes.
Slovenian: Eno pakiranje vsebuje 1, 4 do 6 vnaprej napolnjenih injekcijskih brizg.
English: Use in adult patients receiving peritoneal dialysis Your doctor will maintain your haemoglobin concentration between 10 and 12 g/dl.
Slovenian: Uporaba pri odraslih bolnikihna peritonealni dializi Vaš zdravnik bo vašo koncentracijo hemoglobina ohranjal na vrednosti med 10 in 12 g/dl.
English: Increases in blood potassium have happened in isolated cases.
Slovenian: V posameznih primerih je prišlo do porasta kalija v krvi.
English: 150 IU/kg 3x/week or 450 IU/kg once weekly for 4 weeks
Slovenian: 150 i.e./kg, 3-krat na teden ali 450 i.e./kg, enkrat na teden
English: Good blood management practices should always be used in the perisurgical setting.
Slovenian: V kirurškem okolju se je pri ravnanju s krvjo treba vedno držati dobre prakse.
English: Your doctor may initiate treatment with Silapo if your haemoglobin is 10 g/dl or less.
Slovenian: Vaš zdravnik lahko uvede zdravljenje z zdravilom Silapo, če znaša vaša koncentracija hemoglobina 10 g/dl ali manj.
English: Disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, sodium chloride, calcium chloride dihydrate, polysorbate 20, glycine, leucine, isoleucine, threonine, glutamic acid, phenylalanine, water for injections, sodium hydroxide (pH adjuster), hydrochloric acid (pH adjuster).
Slovenian: Natrijev fosfat dihidrat, natrijev dihidrogenfosfat dihidrat, natrijev klorid, kalcijev klorid dihidrat, polisorbat 20, glicin, levcin, izolevcin, treonin, glutamatna kislina, fenilalanin, voda za injekcije, natrijev hidroksid (za prilagoditev pH), klorovodikova kislina (za prilagoditev pH).
English: Your doctor may monitor your blood pressure regularly while you are using Silapo, particularly at the start of therapy.
Slovenian: Zdravnik lahko med zdravljenjem z zdravilom Silapo redno spremlja vaš krvni tlak, še posebej na začetku zdravljenja.
English: Anaemia symptoms and sequelae may vary with age, gender, and co-morbid medical conditions; a physician's evaluation of the individual patient's clinical course and condition is necessary.
Slovenian: Simptomi anemije in z njo povezane posledice se lahko spreminjajo glede na starost, spol in sočasna bolezenska stanja; zdravnik mora oceniti klinični potek in stanje vsakega posameznega bolnika.
English: Treatment of adult patients scheduled for major elective orthopaedic surgery
Slovenian: Zdravljenje odraslih bolnikov, naročenih na večji elektivni ortopedski kirurški poseg
English: Reticulocyte count increase ≥ 40 000/μl or Hb increase ≥ 1 g/dl
Slovenian: Število retikulocitov zvečano za ≥ 40 000/μl ali zvišanje koncentracije Hb za ≥ 1 g/dl
English: • you had a heart attack or stroke in the month before your treatment
Slovenian: • če ste v preteklem mesecu doživeli miokardni infarkt ali možgansko kap
English: Independent of erythropoietin treatment, thrombotic and vascular events may occur in surgical patients with underlying cardiovascular disease following repeated phlebotomy.
Slovenian: Ne glede na zdravljenje z eritropoetinom lahko pri kirurških bolnikih, ki imajo kardiovaskularne bolezni, pri ponovni flebotomiji pride do tromboze in vaskularnih zapletov.
English: In patients with a baseline haemoglobin of > 13 g/dl, the possibility that Silapo treatment may be associated with an increased risk of postoperative thrombotic/vascular events cannot be excluded.
Slovenian: Pri bolnikih z izhodiščno koncentracijo hemoglobina > 13 g/dl ne moremo izključiti možnosti, da je lahko zdravljenje z zdravilom Silapo povezano z večjim tveganjem za pooperacijske trombotične/žilne dogodke
English: It is recommended that the platelet count is regularly monitored during the first 8 weeks of therapy.
Slovenian: Prvih 8 tednov zdravljenja je priporočljivo redno nadzorovanje števila trombocitov.
English: Correction phase: 50 IU/kg 3 times per week.
Slovenian: Korekcijska faza: 50 i.e./kg trikrat tedensko.
English: Maintenance phase: Dose adjustment in order to maintain haemoglobin (Hb) values at the desired level: Hb between 9.5 and 11 g/dl (5.9-6.8 mmol/l).
Slovenian: Vzdrževalna faza: prilagajanje odmerka, da se vrednosti hemoglobina (Hb) ohranja na želenem nivoju: Hb med 9,5 in 11 g/dl (5,9-6,8 mmol/l).
English: The clinical data available suggest that those patients whose initial haemoglobin is very low (< 6.8 g/dl or < 4.25 mmol/l) may require higher maintenance doses than those whose initial haemoglobin is higher > 6.8 g/dl or> 4.25 mmol/l).
Slovenian: Klinični podatki, ki so na razpolago kažejo, da so za bolnike z zelo nizkim začetnim nivojem hemoglobina (< 6,8 g/dl ali < 4,25 mmol/l) lahko potrebni višji vzdrževalni odmerki kot v primeru manj hude začetne anemije (Hb > 6,8 g/dl ali > 4,25 mmol/l).
English: During treatment with Silapo
Slovenian: Med zdravljenjem z zdravilom Silapo
English: The recommended starting dose is 50 IU/kg.
Slovenian: Priporočeni začetni odmerek je 50 i.e./kg.
English: Always follow these instructions when using Silapo:
Slovenian: Kadar uporabljate zdravilo Silapo, se vedno držite teh navodil:
English: Paediatric patients on haemodialysis
Slovenian: Pediatrični bolniki na hemodializi
English: A tendency towards increased risk estimates for all-cause mortality, cardiovascular and cerebrovascular events associated with higher cumulative ESA doses independent of the diabetes or dialysis status was observed (see sections 4.2 and 4.4).
Slovenian: V povezavi z z večjimi kumulativni odmerki ESA so opazili nagnejnost k povečanemu tveganju za umrljivost zaradi vseh vzrokov ter za kardiovaskularne in cerebrovaskularne dogodke ne glede na sladkorno bolezen ali dializni status (glejte poglavje 4.2 in 4.4).
English: Correction phase 50 IU/kg, 3 times per week by the intravenous route.
Slovenian: Korekcijska faza 50 i.e./kg trikrat tedensko, intravensko.
English: DATE OF FIRST AUTHORISATION / RENEWAL OF THE AUTHORISATION
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Z ZDRAVILOM
English: Chronic renal failure patients
Slovenian: Bolniki s kronično ledvično okvaroo
English: Haemoglobin levels should be closely monitored until a stable level is achieved and periodically thereafter.
Slovenian: Nivo hemoglobina je treba skrbno meriti toliko časa, dokler se nivo ne ustali, potem pa periodično.
English: Reticulocyte count increase < 40 000/μl and Hb increase < 1 g/dl
Slovenian: Število retikulocitov zvečano za < 40 000/μl in zvišanje nivoja Hb za < 1 g/dl
English: Silapo 5 000 IU
Slovenian: Silapo 5 000 i.e.
English: • Cough
Slovenian: • Kašelj.
English: Dose should not be increased over the maximum of 1 050 IU/kg (total dose 80 000 IU) per week.
Slovenian: Odmerka ne smemo povečati toliko, da bi presegel največji odmerek 1050i.e./kg (skupni odmerek 80000i.e.)
English: - blood clotting (thrombotic vascular events) (see section “Warnings and precautions”).
Slovenian: Bolniki z rakom, vključno z odraslimi bolniki z mielodisplastičnim sindromom - Krvni strdki (trombotični žilni dogodki) (glejte poglavje "Opozorila in previdnostni ukrepi").
English: Stop using Silapo if you develop these symptoms and contact your doctor or seek medical attention immediately.
Slovenian: Če se pri vas pojavijo ti simptomi, prenehajte uporabljati zdravilo Silapo in se takoj posvetujte z zdravnikom ali poiščite zdravniško pomoč.
English: Urticaria
Slovenian: Razpon
English: If after an additional 4 weeks of therapy at 300 IU/kg 3 times per week, the haemoglobin has increased ≥ 1 g/dl (0.62 mmol/l) or the reticulocyte count has increased ≥ 40 000 cells/µl the dose should remain at 300 IU/kg 3 times per week.
Slovenian: Če se po dodatnih 4 tednih zdravljenja z 300 i.e./kg trikrat tedensko hemoglobin zviša za najmanj 1 g/dl (0,62 mmol/l) ali če se je število retikulocitov dvignilo ≥40 000 celic/µl, naj odmerek ostane pri 300 i.e./kg trikrat tedensko.
English: Use in adult patients receiving chemotherapy
Slovenian: Uporaba pri odraslih bolniki na kemoterapiji
English: The symptoms are: o unusual tiredness, o feeling dizzy, o breathlessness.
Slovenian: Simptomi so: o neobičajna utrujenost, o omotica, o zasoplost.
English: Patients scheduled for major elective orthopaedic surgery
Slovenian: Bolniki, naročeni na večji elektivni ortopedski kirurški poseg
English: Remove the protective cap from the injection needle and expel air from the syringe and injection needle by holding the syringe vertically and gently pressing the plunger upwards.
Slovenian: Odstranite zaščito za iglo in pazljivo odstranite zrak iz injekcijske brizge tako, da jo držite navpično, bat pa počasi potiskate navzgor, dokler se na konici igle ne pojavi kapljica tekočine.
English: Silapo 1 000 IU/0.3 ml solution for injection in pre-filled syringe Silapo 2 000 IU/0.6 ml solution for injection in pre-filled syringe Silapo 3 000 IU/0.9 ml solution for injection in pre-filled syringe Silapo 4 000 IU/0.4 ml solution for injection in pre-filled syringe Silapo 5 000 IU/0.5 ml solution for injection in pre-filled syringe Silapo 6 000 IU/0.6 ml solution for injection in pre-filled syringe Silapo 8 000 IU/0.8 ml solution for injection in pre-filled syringe Silapo 10 000 IU/1 ml solution for injection in pre-filled syringe Silapo 20 000 IU/0.5 ml solution for injection in pre-filled syringe Silapo 30 000 IU/0.75 ml solution for injection in pre-filled syringe Silapo 40 000 IU/1 ml solution for injection in pre-filled syringe
Slovenian: Silapo 1 000 i.e./0,3 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 2 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 3 000 i.e./0,9 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 4 000 i.e./0,4 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 5 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 6 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 8 000 i.e./0,8 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 10 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 20 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 30 000 i.e./0,75 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 40 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi epoetin zeta
English: Cancer patients are more likely to suffer from blood clots if receiving erythropoietin medicines, like Silapo (see section 4).
Slovenian: Pri bolniki z rakom, ki prejemajo zdravila z eritropoetinom, kot je zdravilo Silapo, se bolj pogosto pojavijo krvni strdki (glej poglavje 4).
English: In cancer patients receiving chemotherapy, the 2-3 week delay between erythropoietin administration and the appearance of erythropoietin-induced red cells should be taken into account when assessing if Silapo therapy is appropriate (patient at risk of being transfused).
Slovenian: Pri rakavih bolnikih na kemoterapiji je treba pri vprašanju, ali je zdravljenje z zdravilom Silapo primerno (bolniki s povečanim tveganjem pri transfuzijah), upoštevati 2-3 tedenski zamik med začetkom dajanja eritropoetina in pojavom eritrocitov, ki jih eritropoetin inducira.
English: Silapo should be administered to patients with symptomatic anaemia (e.g. haemoglobin concentration ≤10 g/dl (6.2 mmol/l)).
Slovenian: Zdravilo Silapo je treba dajati bolnikom s simptomatsko anemijo (npr. koncentracija hemoglobina ≤ 10 g/dl (6,2 mmol/l)).
English: Thrombotic/vascular events, such as myocardial ischaemia, myocardial infarction, cerebrovascular accidents (cerebral haemorrhage and cerebral infarction), transient ischaemic attacks, deep vein thrombosis, arterial thrombosis, pulmonary emboli, aneurysms, retinal thrombosis, and clotting of an artificial kidney have been reported in patients receiving erythropoietic agents.
Slovenian: Pri bolnikih, ki so prejemali eritropoetine, so poročali o trombotičnih/vaskularnih dogodkih, kot so miokardna ishemija, miokardni infarkt, cerebrovaskularni dogodki (možganska krvavitev in možganska kap), tranzitorne ishemične atake, globoka venska tromboza, arterijska tromboza, pljučna embolija, anevrizme, retinalna tromboza in zamašitev umetne ledvice.
English: Pooled post-hoc analyses of clinical studies of ESAs have been performed in CRF patients (on dialysis, not on dialysis, in diabetic and non-diabetic patients).
Slovenian: Združena post hoc analiza kliničnih študij z ESA je bila opravljena pri bolnikih s kronično ledvično odpovedjo (pri bolnikih, ki so na dializi ali niso na dializi, ki imajo sladkorno bolezen ali je nimajo).
English: Disodium phosphate dihydrate Sodium dihydrogen phosphate dihydrate Sodium chloride
Slovenian: 6.1 Seznam pomožnih snovi natrijev fosfat dihidrat natrijev dihidrogenfosfat dihidrat natrijev klorid kalcijev klorid dihidrat polisorbat 20
English: Silapo 20 000 IU
Slovenian: Silapo 20 000 i.e.
English: Subcutaneous route
Slovenian: Subkutano dajanja
English: Remember to tell your doctor that you are receiving Silapo if you have to visit the hospital or family doctor for any treatment including a blood test, as Silapo may affect the results.
Slovenian: Če morate v bolnico ali k svojemu družinskemu zdravniku zaradi zdravljenja, ki vključuje krvne teste, povejte zdravniku, da jemljete zdravilo Silapo, ker lahko zdravilo Silapo vpliva na rezultate.
English: In addition, special precaution should be taken in patients with predisposition for development of DVTs.
Slovenian: Poleg tega je pri bolnikih s predispozicijo za nastanek globoke venske tromboze (DVT -deep vein trombosis) potrebna posebna previdnost.
English: Depending on how your anaemia responds to treatment, the dose may be adjusted approximately every 4 weeks until your condition is controlled.
Slovenian: Odvisno od tega, kako se anemija odziva na zdravljenje, se bo odmerek prilagajal približno vsake štiri tedne, dokler Vaše stanje ne bo pod nadzorom.
English: Adult cancer patients with symptomatic anaemia receiving chemotherapy
Slovenian: Odrasli bolniki z rakom in s simptomatsko anemijo, ki se zdravijo s kemoterapijo
English: Moreover, in patients with a baseline haemoglobin of > 13 g/dl, the possibility that epoetin zeta treatment may be associated with an increased risk of postoperative thrombotic/vascular events cannot be excluded.
Slovenian: Pri bolnikih z izhodiščno koncentracijo hemoglobina >13g/dl ni mogoče izključiti možnosti, da je zdravljenje z epoetinom zetalahko povezano s povečanim tveganjem za pooperativne trombotične žilne dogodke.