FrancophonIA/ELRC3.0 huggingface dataset:
English: Therefore, it is recommended that the platelet counts be measured before the initiation of therapy with enoxaparin sodium and then regularly thereafter during the treatment.
Croatian: Stoga se preporučuje odrediti broj trombocita prije početka liječenja enoksaparinnatrijem i redovito ga kontrolirati tijekom liječenja.
English: Use of heparin is usually not recommended in patients with acute infective endocarditis due to the risk of cerebral haemorrhage.
Croatian: Primjena heparina obično se ne preporučuje u bolesnika s akutnim infektivnim endokarditisom, zbog rizika od cerebralnog krvarenja.
English: Both enoxaparin sodium regimens were equivalent to standard heparin therapy in reducing the risk of recurrent venous thromboembolism (DVT and/or PE).
Croatian: Oba režima liječenja enoksaparinnatrijem bila su ekvivalentna liječenju standardnim heparinom s obzirom na smanjenje rizika od rekurentne venske tromboembolije (DVT-a i/ili PE-a).
English: A. MANUFACTURER(S) OF THE BIOLOGICAL ACTIVE SUBSTANCE(S) AND MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE
Croatian: PROIZVOĐAČ(I) BIOLOŠKE(IH) DJELATNE(IH) TVARI I PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE
English: If you are not sure what to do, talk to your doctor or nurse immediately.
Croatian: Ako niste sigurni odmah se obratite liječniku ili medicinskoj sestri.
English: • Hypersensitivity to enoxaparin sodium, heparin or its derivatives, including other low molecular weight heparins (LMWH) or to any of the excipients listed in section 6.1;
Croatian: • preosjetljivošću na enoksaparinnatrij, heparin ili njegove derivate, uključujući druge heparine niske molekulske mase ili neku od pomoćnih tvari navedenih u dijelu 6.1
English: • Increases in liver enzymes.
Croatian: • porast razina jetrenih enzima
English: In comparison with heparin, enoxaparin sodium significantly reduced the combined incidence of angina pectoris, myocardial infarction and death, with a decrease of 19.8 to 16.6% (relative risk reduction of 16.2%) on day 14.
Croatian: U usporedbi s heparinom, enoksaparinnatrij je značajno snizio kombiniranu incidenciju angine pektoris, infarkta miokarda i smrti, uz sniženje s 19,8 na 16,6% (smanjenje relativnog rizika: 16,2%) 14. dana.
English: Studies conducted in pregnant rats and rabbits at SC doses of enoxaparin sodium up to 30 mg/kg/day did not reveal any evidence of teratogenic effects or foetotoxicity.
Croatian: Ispitivanja provedena na skotnim ženkama štakora i kunića pri supkutanim dozama enoksaparinnatrija do 30 mg/kg/dan nisu otkrila dokaze teratogenih učinaka ni fetotoksičnosti.
English: 7) Press down on the plunger with your finger.
Croatian: 7) Prstom pritisnite klip prema dolje.
English: Treatment of acute STEMI (patients over 75)
Croatian: Liječenje akutnog STEMI-ja (bolesnici stariji od 75 godina)
English: Treatment of unstable angina and NSTEMI
Croatian: Liječenje nestabilne angine i NSTEMI-ja
English: • The dose will depend on how likely you are to develop a clot.
Croatian: • Doza će ovisiti o tome kolika je vjerojatnost nastanka krvnog ugruška.
English: Thorinane should not be used interchangeably with other medicines belonging to the group of low molecular weight heparins.
Croatian: Thorinane se ne smije međusobno zamjenjivati s drugim lijekovima iz skupine heparina niske molekulske mase.
English: The effect of this dose is usually sufficient for a 4-hour session; however, if fibrin rings are found, for example after a longer than normal session, a further dose of 50 IU to 100 IU/kg (0.5 to 1 mg/kg) may be given.
Croatian: Učinak te doze obično je dovoljan za 4-satnu dijalizu; međutim, ako se utvrde fibrinski prstenovi, npr. nakon dijalize koja traje dulje nego što je uobičajeno, može se primijeniti dodatna doza od 50 do 100 IU/kg (0,5 do 1 mg/kg).
English: The enoxaparin sodium dosing strategy was adjusted for severe renally impaired patients and for the elderly of at least 75 years of age.
Croatian: Strategija doziranja enoksaparinnatrija bila je prilagođena u bolesnika s teškim oštećenjem bubrežne funkcije i starijih bolesnika u dobi od najmanje 75 godina.
English: Enoxaparin sodium is a biological substance obtained by alkaline depolymerization of heparin benzyl ester derived from porcine intestinal mucosa.
Croatian: Enoksaparinnatrij je biološka tvar koja se dobiva alkalnom depolimerizacijom benzilnog estera heparina dobivenog iz sluznice svinjskog crijeva.
English: If there is a need for earlier than 12 hours enoxaparin sodium preoperative prophylactic initiation (e.g. high risk patient waiting for a deferred orthopaedic surgery), the last injection should be administered no later than 12 hours prior to surgery and resumed 12 hours after surgery.
Croatian: Ako je potrebno započeti profilaksu enoksaparinnatrijem više od 12 sati prije operacije (npr. u visokorizičnih bolesnika koji čekaju na odgođen ortopedski kirurški zahvat), posljednja se injekcija mora primijeniti najmanje 12 sati prije kirurškog zahvata, a sljedeća 12 sati nakon njega.
English: Supplied in packs of 2 or 10 pre-filled syringes.
Croatian: Dostupno u pakiranjima od 2 ili 10 napunjenih štrcaljki.
English: These include ATIII-dependent inhibition of other coagulation factors like factor VIIa, induction of endogenous Tissue Factor Pathway Inhibitor (TFPI) release as well as a reduced release of von Willebrand factor (vWF) from the vascular endothelium into the blood circulation.
Croatian: Ona uključuju o ATIII ovisnu inhibiciju drugih faktora zgrušavanja, primjerice faktora VIIa, indukciju otpuštanja endogenog inhibitora puta tkivnog faktora (engl. tissue factor pathway inhibitor, TFPI), kao i smanjeno otpuštanje von Willebrandova faktora (vWF) iz krvožilnog endotela u krvotok.
English: As with other anticoagulants, haemorrhage may occur in the presence of associated risk factors such as: organic lesions liable to bleed, invasive procedures or the concomitant use of medications affecting haemostasis (see sections 4.4 and 4.5).
Croatian: Kao i kod drugih antikoagulansa, krvarenje može nastupiti ako su prisutni s njime povezani faktori rizika poput: organskih lezija sklonih krvarenju, invazivnih postupaka ili istodobne primjene lijekova koji utječu na hemostazu (vidjeti dijelove 4.4 i 4.5).
English: • You notice yellowing of your skin or eyes and your urine becomes darker in colour.
Croatian: • žuta boja kože ili očiju i tamnija boja mokraće.
English: In the in vitro purified system, enoxaparin sodium has a high anti-Xa activity (approximately 100 IU/mg) and low anti-IIa or anti thrombin activity (approximately 28 IU/mg), with a ratio of 3.6.
Croatian: U pročišćenom sustavu in vitro, enoksaparinnatrij ostvaruje snažnu anti-Xa aktivnost (približno 100 IU/mg) i slabu anti-IIa ili antitrombinsku aktivnost (približno 28 IU/mg), uz omjer od 3,6.
English: After dilution is completed, the volume to be injected can be calculated using the following formula [Volume of diluted solution (mL) = Patient weight (kg) x 0.1] or using the table below.
Croatian: Nakon završetka razrjeđivanja, volumen koji treba injicirati može se izračunati korištenjem sljedeće jednadžbe [volumen razrijeđene otopine (ml) = bolesnikova tjelesna težina (kg) x 0,1] ili tablice u nastavku.
English: • you have had an operation recently on your eyes or brain • you are elderly (over 65 years old) and especially if you are over 75 years old
Croatian: • ako ste starije dobi (stariji od 65 godina), osobito ako imate više od 75 godina
English: Treatment in patients with DVT with or without PE
Croatian: Liječenje u bolesnika s DVT-om praćenim PE-om ili bez njega
English: When administered in conjunction with a thrombolytic (fibrin specific or non-fibrin specific), enoxaparin sodium should be given between 15 minutes before and 30 minutes after the start of fibrinolytic therapy.
Croatian: Kada se primjenjuje u kombinaciji s trombolitikom (neovisno o tome je li specifičan za fibrin ili ne), enoksaparinnatrij treba primijeniti u razdoblju od 15 minuta prije do 30 minuta nakon početka fibrinolitičke terapije.
English: Water for injections.
Croatian: Voda za injekciju.
English: o For patients who undergo major orthopaedic surgery an extended thromboprophylaxis up to 5 weeks is recommended.
Croatian: o Za bolesnike koji se podvrgavaju velikom ortopedskom kirurškom zahvatu preporučuje se produljena tromboprofilaksa u trajanju do 5 tjedana.
English: No data are available in patients using enoxaparin sodium for prophylaxis or treatment and during haemodialysis sessions.
Croatian: Nema dostupnih podataka o bolesnicima u kojih se enoksaparinnatrij primjenjuje za profilaksu ili liječenje i tijekom postupaka hemodijalize.
English: • Rare: Cases of immuno-allergic thrombocytopenia with thrombosis; in some of them thrombosis was complicated by organ infarction or limb ischaemia (see section 4.4).
Croatian: • Rijetko: slučajevi imunoalergijske trombocitopenije s trombozom; u nekima od tih slučajeva tromboza je dovela do komplikacija infarkta organa ili ishemije ekstremiteta (vidjeti dio 4.4)
English: Injection site nodules* (inflammatory nodules, which were not cystic enclosure of enoxaparin).
Croatian: Noduli na mjestu injiciranja* (upalni noduli, koji nisu cistične tvorevine koje sadrže enoksaparin).
English: If you think that you have used too much or too little Thorinane, tell your doctor, nurse or pharmacist immediately, even if you have no signs of a problem.
Croatian: Ako primijenite više lijeka Thorinane nego što ste trebali Ako mislite da ste primijenili previše ili premalo lijeka Thorinane, odmah se obratite svom liječniku, medicinskoj sestri ili ljekarniku, čak i ako nemate znakova tegoba.
English: Injection should be made preferably when the patient is lying down.
Croatian: Poželjno je primijeniti injekciju dok je bolesnik u ležećem položaju.
English: This can lead to a loss of the medicine.
Croatian: Tako možete istisnuti lijek.
English: • Prophylaxis of venous thromboembolic disease in medical patients with an acute illness (such as acute heart failure, respiratory insufficiency, severe infections or rheumatic diseases) and reduced mobility at increased risk of venous thromboembolism.
Croatian: • profilaksu venske tromboembolijske bolesti u medikamentozno liječenih bolesnika s akutnom bolešću (kao što su akutno zatajenje srca, respiratorna insuficijencija, teške infekcije ili reumatske bolesti) i smanjenom pokretljivošću u kojih je povećan rizik od venske tromboembolije
English: • Rare: Cholestatic liver injury*
Croatian: • Rijetko: kolestatsko oštećenje jetre*
English: When non-weight adjusted dosing was administered, it was found after a single-SC 4,000 IU (40 mg) dose, that anti-Xa exposure is 52% higher in low-weight women (<45 kg) and 27% higher in low-weight men (<57 kg) when compared to normal weight control subjects (see section 4.4).
Croatian: Kod primjene doza koje nisu bile prilagođene prema tjelesnoj težini, nakon jednokratne supkutane doze od 4000 IU (40 mg) utvrđeno je da je izloženost anti-Xa aktivnosti bila 52% veća kod žena niske tjelesne težine (< 45 kg) i 27% veća kod muškaraca niske tjelesne težine (< 57 kg) u usporedbi s kontrolnim ispitanicima normalne tjelesne težine (vidjeti dio 4.4).
English: Plasma anti-IIa activity after SC administration is approximately ten-fold lower than anti-Xa activity.
Croatian: Plazmatska anti-IIa aktivnost nakon supkutane primjene približno je desetostruko niža nego anti-Xa aktivnost.
English: Method of administration Thorinane should not be administered by the intramuscular route.
Croatian: Način primjene Thorinane ne smije se primijenjivati intramuskularnim putem.
English: However, your doctor may give you a futher dose of 50 IU to 100 IU (0.5 to 1 mg) for every kilogram of your weight, if necessary.
Croatian: Međutim, liječnik će Vam možda dati i dodatnu dozu od 50 - 100 IU (0,5 - 1 mg) po kilogramu tjelesne težine, ako to bude potrebno.
English: It is recommended to prepare the dilution immediately before use.
Croatian: Razrjeđivanje se preporučuje provesti neposredno prije primjene.
English: These factors are known to contribute to the overall antithrombotic effect of enoxaparin sodium.
Croatian: Poznato je da ti faktori pridonose sveukupnom antitrombotskom učinku enoksaparinnatrija.
English: • An initial dose of 3,000 IU (30 mg) of Thorinane will be given as injection into your vein.
Croatian: • Primit ćete početnu dozu od 3000 IU (30 mg) lijeka Thorinane injekcijom u venu.
English: In these patients, careful clinical monitoring is advised, and biological monitoring by antiXa activity measurement might be considered (see sections 4.2 and 5.2).
Croatian: U tih se bolesnika preporučuje pažljivo kliničko praćenje, a može se razmotriti i biološko praćenje određivanjem anti-Xa aktivnosti (vidjeti dijelove 4.2 i 5.2).
English: Pregnant women with mechanical prosthetic heart valves may be at higher risk for thromboembolism.
Croatian: Trudnice s mehaničkim umjetnim srčanim zaliscima mogu imati povećan rizik od tromboembolije.
English: Heparin aPTT Adjusted IV Therapy n (%)
Croatian: Heparinintravenska terapija prilagođena prema aPTV-u n (%)
English: This is more likely to happen in people with kidney problems or diabetes.
Croatian: Vjerojatnije je da će se javiti u osoba s bubrežnim tegobama ili šećernom bolešću.
English: Treatment in patients with acute STEMI
Croatian: Liječenje u bolesnika s akutnim STEMI-jem
English: Oral anticoagulant therapy should be initiated when appropriate (see “Switch between enoxaparin sodium and oral anticoagulants” at the end of section 4.2).
Croatian: Kada je to prikladno, treba uvesti liječenje oralnim antikoagulansima (vidjeti odlomak "Prelazak s enoksaparinnatrija na oralne antikoagulanse i obratno" na kraju dijela 4.2).
English: • An increase in the number of eosinophils in your blood.
Croatian: • povećan broj eozinofila u krvi.
English: • Uncommon: Local irritation, skin necrosis at injection site
Croatian: • Manje često: lokalna nadraženost; nekroza kože na mjestu injiciranja
English: • IV (bolus) injection (for acute STEMI indication only):
Croatian: • Intravenska (bolusna) injekcija (samo za akutni STEMI):
English: 4.1 Therapeutic indications
Croatian: Klinički podaci 4.1 Terapijske indikacije
English: The pharmacokinetic parameters of enoxaparin sodium have been studied primarily in terms of the time course of plasma anti-Xa activity and also by anti-IIa activity, at the recommended dosage ranges after single and repeated SC administration and after single IV administration.
Croatian: Farmakokinetički parametri enoksaparinnatrija prvenstveno su se ocjenjivali s obzirom na vremensku krivulju plazmatske anti-Xa aktivnosti, kao i anti-IIa aktivnosti, pri preporučenim rasponima doza nakon jednokratne i ponovljene supkutane primjene te nakon jednokratne intravenske primjene.
English: If you forget to use Thorinane
Croatian: Ako ste zaboravili primijeniti Thorinane
English: • Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), excluding PE likely to require thrombolytic therapy or surgery.
Croatian: • liječenje duboke venske tromboze (DVT) i plućne embolije (PE), osim PE-a koji će vjerojatno zahtijevati trombolitičko liječenje ili kirurški zahvat
English: • A feeling of tenderness and swelling in your stomach.
Croatian: • osjetljivost na dodir i oticanje u području trbuha.
English: This study included patients with heart failure (NYHA Class III or IV); acute respiratory failure or complicated chronic respiratory insufficiency, and acute infection or acute rheumatic; if associated with at least one VTE risk factor (age ≥75 years, cancer, previous VTE, obesity, varicose veins, hormone therapy, and chronic heart or respiratory failure).
Croatian: U tom su ispitivanju sudjelovali bolesnici sa zatajenjem srca (NYHA kategorije III ili IV), akutnim respiratornim zatajenjem ili kompliciranom kroničnom respiratornom insuficijencijom te akutnom infekcijom ili akutnom reumatskom bolešću, povezanima s najmanje jednim faktorom rizika za VTE (dob ≥ 75 godina, rak, prethodni VTE, pretilost, varikozne vene, hormonska terapija te kronično srčano ili respiratorno zatajenje).
English: As there is an interval before the VKA reaches its maximum effect, enoxaparin sodium therapy should be continued at a constant dose for as long as necessary in order to maintain the INR within the desired therapeutic range for the indication in two successive tests.
Croatian: K postigne svoj maksimalan učinak, liječenje enoksaparinnatrijem treba nastaviti u stalnoj dozi onoliko dugo koliko je potrebno da se INR održi unutar željenog terapijskog raspona za određenu indikaciju u dva uzastopna testa.
English: Your doctor will request you perform blood tests called INR and tell you when to start Thorinane accordingly.
Croatian: Vaš će liječnik tražiti da napravite krvne pretrage za određivanje parametra koji se zove INR i reći će Vam kada trebate početi primjenjivati Thorinane u skladu s nalazima tih pretraga.
English: 5) Hold the syringe in the hand you write with (like a pencil) and with your other hand, gently pinch the cleaned area of your abdomen between your forefinger and thumb to make a fold in the skin.
Croatian: 5) Dok štrcaljku držite rukom kojom pišete (poput olovke), palcem i kažiprstom druge ruke na očišćenom dijelu kože trbuha načinite nabor kože.
English: Enoxaparin sodium or standard heparin therapy was administered for a minimum of 5 days and until the targeted warfarin sodium INR was achieved.
Croatian: Liječenje enoksaparinnatrijem ili standardnim heparinom primjenjivalo se tijekom najmanje 5 dana i do postizanja ciljnog INR-a uz varfarinnatrij.
English: • Medicines which increase potassium level in your blood such as potassium salts, water pills, some medicines for heart problems.
Croatian: • lijekove koji povisuju razinu kalija u krvi, kao što su soli kalija, tablete za izmokravanje (diuretici) i neki lijekovi za srčane tegobe
English: If there are clinical symptoms suggestive of HIT (any new episode of arterial and/or venous thromboembolism, any painful skin lesion at the injection site, any allergic or anaphylactoid reactions on treatment), platelet count should be measured.
Croatian: Ako postoje klinički simptomi koji ukazuju na HIT (bilo koja nova epizoda arterijske i/ili venske tromboembolije, bolna kožna lezija na mjestu injiciranja te alergijska ili anafilaktoidna reakcija tijekom liječenja), treba odrediti broj trombocita.
English: No pharmacokinetic interactions were observed between enoxaparin sodium and thrombolytics when administered concomitantly.
Croatian: Nisu primijećene farmakokinetičke interakcije između enoksaparinnatrija i trombolitika pri njihovoj istodobnoj primjeni.
English: • Switch between enoxaparin sodium and vitamin K antagonists (VKA) Clinical monitoring and laboratory tests [prothrombin time expressed as the International Normalized Ratio (INR)] must be intensified to monitor the effect of VKA.
Croatian: • Prelazak s enoksaparinnatrija na antagoniste vitamina K i obratno Kliničko praćenje i laboratorijske pretrage (protrombinsko vrijeme izraženo kao internacionalni normalizirani omjer [engl. international normalized ratio, INR] moraju se intenzivirati radi praćenja učinka antagonista vitamina K.
English: The dose regimen of 150 IU/kg (1.5 mg/kg) administered once daily should be used in uncomplicated patients with low risk of VTE recurrence.
Croatian: Režim doziranja od 150 IU/kg (1,5 mg/kg) jedanput na dan treba koristiti u bolesnika bez komplikacija u kojih je rizik od ponovne pojave VTE-a nizak.
English: IV (Bolus) Injection (for acute STEMI indication only):
Croatian: Intravenska (bolusna) injekcija (samo za akutni STEMI):
English: • The maximum amount of Thorinane given for the first two injections is 7,500 IU (75 mg).
Croatian: • Maksimalna doza lijeka Thorinane koju ćete primiti u prve dvije injekcije je 7500 IU
English: For all indications except STEMI, no dose reduction is necessary in the elderly patients, unless kidney function is impaired (see below “renal impairment” and section 4.4).
Croatian: Kod svih indikacija osim STEMI-ja nije potrebno prilagođavati dozu u starijih bolesnika, osim ako im je narušena bubrežna funkcija (vidjeti odlomak "Oštećenje funkcije bubrega" u nastavku i dio 4.4).
English: To reduce the potential risk of bleeding associated with the concurrent use of enoxaparin sodium and epidural or spinal anaesthesia/analgesia or spinal puncture, consider the pharmacokinetic profile of enoxaparin sodium (see section 5.2).
Croatian: Da bi se smanjio mogući rizik od krvarenja povezanog s primjenom enoksaparinnatrija tijekom epiduralne ili spinalne anestezije/analgezije ili spinalne punkcije, treba uzeti u obzir farmakokinetički profil enoksaparinnatrija (vidjeti dio 5.2).
English: • Treat blood clots that are in your blood
Croatian: • liječenje krvnih ugrušaka koji se nalaze u krvi
English: Treatment of acute STEMI (patients under 75)
Croatian: Liječenje akutnog STEMI-ja (bolesnici mlađi od 75 godina)
English: Do not use Thorinane
Croatian: Nemojte primjenjivati Thorinane
English: Heparins can suppress adrenal secretion of aldosterone leading to hyperkalaemia (see section 4.8), particularly in patients such as those with diabetes mellitus, chronic renal failure, pre-existing metabolic acidosis, taking medicinal products known to increase potassium (see section 4.5).
Croatian: Heparin može suprimirati lučenje aldosterona iz nadbubrežne žlijezde i tako dovesti do hiperkalijemije (vidjeti dio 4.8), osobito u bolesnika sa šećernom bolešću, kroničnim zatajenjem bubrega i otprije postojećom metaboličkom acidozom te bolesnika koji uzimaju lijekove za koje se zna da povisuju razinu kalija (vidjeti dio 4.5).
English: D. CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE
Croatian: UVJETI ILI OGRANIČENJA VEZANI UZ SIGURNU I
English: • If you have any sign of blockage of a blood vessel by a blood clot such as: - cramping pain, redness, warmth, or swelling in one of your legs - these are symptoms of deep vein thrombosis - breathlessness, chest pain, fainting or coughing up blood - these are symptoms of a pulmonary embolism
Croatian: • Ako imate bilo koji znak začepljenja krvne žile krvnim ugruškom, kao što su: - bolni grčevi, crvenilo, toplina ili oticanje jedne noge - to su simptomi duboke venske tromboze - nedostatak zraka, bol u prsnom košu, nesvjestica ili iskašljavanje krvi - to su simptomi plućne embolije
English: After 12 hours of the enoxaparin sodium injection, protamine administration may not be required.
Croatian: Ako je od injekcije enoksaparinnatrija prošlo 12 sati, primjena protamina možda ni neće biti potrebna.
English: Diluted medicinal product with sodium chloride 9 mg/ml (0.9%) solution for injection or 5% glucose 8 hours
Croatian: Lijek razrijeđen otopinom natrijeva klorida 9 mg/ml (0,9 %) za injekciju ili 5 %-tnom glukozom 8 sati
English: Should the physician decide to administer anticoagulation in the context of epidural or spinal anaesthesia/analgesia or lumbar puncture, frequent monitoring must be exercised to detect any signs and symptoms of neurological impairment such as midline back pain, sensory and motor deficits (numbness or weakness in lower limbs), bowel and/or bladder dysfunction.
Croatian: Ako liječnik odluči primijeniti antikoagulans u kontekstu epiduralne ili spinalne anestezije/analgezije ili lumbalne punkcije, moraju se provoditi česte kontrole kako bi se uočili bilo kakvi znakovi i simptomi neuroloških oštećenja, kao što su bol u središnjem dijelu leđa, senzorni i motorički deficiti (utrnulost ili slabost u donjim ekstremitetima) te disfunkcija crijeva i/ili mokraćnog mjehura.
English: There are no clinical data for enoxaparin sodium in fertility.
Croatian: Nema kliničkih podataka o utjecaju enoksaparinnatrija na plodnost.
English: If the treatment with enoxaparin sodium is to be continued, the next scheduled dose should be given no sooner than 6 to 8 hours after sheath removal.
Croatian: Ako treba nastaviti liječenje enoksaparinnatrijem, sljedeća doza prema rasporedu smije se primijeniti tek 6 do 8 sati nakon uklanjanja uvodnice.
English: It is not known whether unchanged enoxaparin is excreted in human breast milk.
Croatian: Nije poznato izlučuje li se enoksaparin u neizmijenjenu obliku u majčino mlijeko u ljudi.