FrancophonIA/ELRC3.0 huggingface dataset:
English: - Depending upon the results of these tests, your doctor may change/adjust the number of hard capsules you or the child you are caring for take, prescribe a different pack size of this medicine, and/or change the length of time to take this treatment.
Croatian: - Ovisno o rezultatima tih pretraga, liječnik može promijeniti/prilagoditi broj tvrdih kapsula koje uzimate Vi ili dijete o kojem skrbite, propisati drugu veličinu pakiranja ovog lijeka i/ili promijeniti duljinu trajanja liječenja.
English: Try not to let the oral syringe touch the inside of the mouth.
Croatian: Pazite da štrcaljkom za usta ne dotaknete unutrašnjost usta.
English: Hard capsule (capsule)
Croatian: Tvrda kapsula (kapsula)
English: What you need to know before you use Rebetol
Croatian: Što morate znati prije nego počnete uzimati Rebetol
English: What Rebetol contains
Croatian: Što Rebetol sadrži
English: HCV-RNA negative
Croatian: HCV-RNK negativna
English: Discontinue breast-feeding before starting to take this medicine.
Croatian: Prekinite dojenje prije početka uzimanja ovog lijeka.
English: It is unknown whether the Rebetol that is contained in sperm will exert its potential teratogenic or genotoxic effects on the human embryo/foetus.
Croatian: Nije poznato hoće li Rebetol sadržan u spermi iskazati potencijalno teratogene ili genotoksične učinke na ljudski embrij/fetus.
English: If you are not sure, talk to your doctor or pharmacist before taking Rebetol.
Croatian: Ako niste sigurni, obratite se svom liječniku ili ljekarniku prije nego uzmete Rebetol.
English: • Inability to achieve full adult height may occur in some children and adolescents
Croatian: • nesposobnost postizanja pune visine za odraslu dob se moze pojaviti u neke djece i adolescenata
English: Prior Response Relapse
Croatian: Prethodni odgovor Relaps
English: Genotype 2, 3**
Croatian: Genotip 2, 3**
English: The use of Rebetol is contraindicated during pregnancy.
Croatian: Primjena lijeka Rebetol kontraindicirana je tijekom trudnoće.
English: • have HIV (human immunodeficiency virus) or have ever had any other problems with your immune system.
Croatian: • imate HIV (virus humane imunodeficijencije) ili ste nekada imali nekih drugih tegoba s imunološkim sustavom.
English: D. Take the oral syringe out of the bottle and check to see that the correct amount appears in the bottom of the syringe.
Croatian: D. Izvadite štrcaljku za usta iz bočice i provjerite da se na dnu štrcaljke nalazi točna količina lijeka.
English: Response week 12 % (n/N)
Croatian: Odgovor u 12. tjednu % (n/N)
English: All Genotypes Genotype 1 Genotype 2 Genotype 3 Genotype 4
Croatian: Svi genotipovi Genotip 1 Genotip 2 Genotip 3 Genotip 4
English: Rebetol must be used in combination therapy as described in section 4.1.
Croatian: Rebetol se mora koristiti u kombiniranoj terapiji, kako je opisano u dijelu 4.1.
English: However, in a population pharmacokinetic study, age was not a key factor in the kinetics of ribavirin; renal function is the determining factor.
Croatian: Međutim, u ispitivanju populacijske farmakokinetike dob nije bila ključni čimbenik u kinetici ribavirina; odlučujući čimbenik bila je funkcija bubrega.
English: Each capsule contains a small amount of lactose.
Croatian: Svaka kapsula sadrži malu količinu laktoze.
English: Rebetol capsules are packaged in blisters consisting of polyvinyl chloride (PVC)/polyethylene (PE)/polyvinylidene chloride (PVdC).
Croatian: Rebetol kapsule pakirane su u blistere od polivinilklorid (PVC)/polietilen (PE)/poliviniliden klorida (PVdC).
English: 1 capsule in the morning and 2 capsules in the evening
Croatian: 1 kapsula ujutro i 2 kapsule navečer
English: Reduce Rebetol dose* if:
Croatian: Smanjiti dozu lijeka Rebetol* ako je:
English: By Week 12*** (n= 915)
Croatian: Do 12. tjedna*** (n=915)
English: The high sustained response rate in this subgroup of patients was identified in an interim analysis (n=49) and prospectively confirmed (n=48).
Croatian: Visoka stopa trajnog odgovora u ovoj podskupini bolesnika utvrđena je preliminarnom analizom (n=49) te je prospektivno potvrđena (n=48).
English: In this subgroup, there was a 56 % (463/823) sustained virological response rate.
Croatian: U toj je podskupini stopa trajnog virološkog odgovora iznosila 56% (463/823).
English: In all three treatment groups, sustained virologic response rates were similar.
Croatian: U sve su tri liječene skupine stope trajnog virološkog odgovora bile slične.
English: • are allergic to ribavirin or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na ribavirin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: Although not all of these unwanted effects may occur, they may need medical attention if they do occur.
Croatian: Premda se ne moraju pojaviti sve ove nuspojave, ako se pojave, možda će Vam biti potrebna liječnička pomoć.
English: This medicine does not affect your ability to drive or use machines; however, other medicines used in combination with Rebetol may affect your ability to drive or use machines.
Croatian: Ovaj lijek ne utječe na sposobnost upravljanja vozilima ili strojevima, međutim, drugi lijekovi koji se primjenjuju u kombinaciji s lijekom Rebetol mogu utjecati na Vašu sposobnost upravljanja vozilima ili strojevima.
English: Genotype 1 (n = 92) Genotype 2/3/4 (n = 26)
Croatian: Genotip 1 (n = 92) Genotip 2/3/4 (n = 26)
English: C. Pull the rod out until you can read the correct number of mL for the dose you are measuring.
Croatian: C. Izvlačite klip sve dok ne vidite točan broj mililitara za dozu koju odmjeravate.
English: However, if a week 12 response was achieved, there was little difference in SVR regardless of prior treatment or prior response.
Croatian: Međutim, ako je u 12. tjednu odgovor postignut, nije bilo velike razlike u trajnom virološkom odgovoru bez obzira na prijašnje liječenje ili prijašnji odgovor.
English: Limited historical data indicate that treatment for 48 weeks might be associated with a higher sustained response rate (11/11) and with a lower risk of relapse (0/11 as compared to 7/96 following 24 weeks of treatment).
Croatian: Ograničeni prethodni podaci ukazuju na to da bi liječenje u trajanju od 48 tjedana moglo biti povezano s većom stopom trajnog odgovora (11/11) i manjim rizikom od relapsa (0/11 u usporedbi sa 7/96 nakon 24 tjedna liječenja).
English: Positive
Croatian: Pozitivno
English: If it gets worse, your doctor will decide whether or not your Rebetol treatment needs to be changed.
Croatian: Ako se infekcija pogoršava, liječnik će odlučiti treba li promijeniti liječenje lijekom Rebetol ili ne.
English: Do not use this medicine without advice of your doctor or pharmacist if you notice any change in the appearance of the hard capsules.
Croatian: Nemojte koristiti ovaj lijek bez savjetovanja s liječnikom ili ljekarnikom ako primijetite bilo kakvu promjenu u izgledu tvrdih kapsula.
English: th percentile).
Croatian: 13 percentila).
English: Rebetol accumulates intracellularly and is cleared from the body very slowly.
Croatian: Rebetol se nakuplja unutar stanica i vrlo sporo se uklanja iz organizma.
English: Immediate packaging (blister foil)
Croatian: Unutarnje pakiranje (blister folija)
English: The overall sustained response rate after a 24-week treatment duration was 50 %.
Croatian: Ukupna stopa trajnog terapijskog odgovora nakon 24 tjedna liječenja iznosio je 50%.
English: This medicine is a white, opaque, hard capsule imprinted with blue ink.
Croatian: Ovaj lijek je bijela, neprozirna tvrda kapsula s oznakama otisnutima plavom bojom.
English: Male: impotence, prostatitis, erectile dysfunction.
Croatian: Muškarci: impotencija, prostatitis, erekcijska disfunkcija.
English: Elderly patients ( 65 years of age)
Croatian: Stariji bolesnici (≥65 godina)
English: As in adult patients, children and adolescents also experienced other psychiatric adverse reactions (e.g., depression, emotional lability, and somnolence) (see section 4.4).
Croatian: Kao i odrasli bolesnici, djeca i adolescenti su imali i druge psihijatrijske nuspojave (npr. depresiju, emocionalnu labilnost i somnolenciju) (vidjeti dio 4.4).
English: Men whose partners are pregnant must be instructed to use a condom to minimise delivery of Rebetol to the partner.
Croatian: Muškarce čije su partnerice trudne mora se uputiti da koriste prezervativ kako bi se prijenos lijeka Rebetol u tijelo partnerice smanjio na najmanju moguću mjeru.
English: Swallow the dose.
Croatian: Progutajte lijek.
English: No sustained Response
Croatian: Bez trajnog odgovora
English: Ribavirin (Rebetol) is a synthetic nucleoside analogue which has shown in vitro activity against some RNA and DNA viruses.
Croatian: Ribavirin (Rebetol) je sintetski analog nukleozida koji je pokazao aktivnost in vitro protiv nekih RNK i DNK virusa.
English: Ribavirin has two pathways of metabolism: 1) a reversible phosphorylation pathway; 2) a degradative pathway involving deribosylation and amide hydrolysis to yield a triazole carboxyacid metabolite.
Croatian: Ribavirin ima dva metabolička puta: 1) put reverzibilne fosforilacije; 2) put razgradnje koji uključuje deribozilaciju i hidrolizu amida, u kojem nastaje metabolit triazol karboksilna kiselina.
English: Seizure (convulsion)
Croatian: napadaji (konvulzije)
English: Elderly ( 65 years of age)
Croatian: Stariji (≥65 godina)
English: For children or adolescents who cannot swallow a hard capsule, an oral solution of this medicine is available.
Croatian: Za djecu ili adolescente koji ne mogu progutati tvrdu kapsulu, ovaj je lijek dostupan u obliku oralne otopine.
English: Rebetol should be administered orally with food.
Croatian: Rebetol se mora primijeniti peroralno, uz obrok.
English: Dosing of Rebetol for children and adolescent patients is determined by the patient body weight.
Croatian: Doziranje lijeka Rebetol za djecu i adolescente određuje se prema tjelesnoj težini bolesnika.
English: 2, rue Louis Pasteur 14200 Hérouville-Saint-Clair France
Croatian: 2, rue Louis Pasteur 14200 Hérouville-Saint-Clair Francuska
English: B. While keeping the tip in the liquid, pull the rod out.
Croatian: Držeći vrh štrcaljke unutar tekućine, izvlačite klip.
English: In this subgroup, there was a 92 % (89/97) sustained virological response rate.
Croatian: U toj je podskupini stopa trajnog terapijskog odgovora iznosila 92% (89/97).
English: Pain in extremity, back pain, muscle contracture
Croatian: bol u ekstremitetima, bol u leđima, mišićne kontrakture
English: 2 capsules in the morning and 2 capsules in the evening See adult dose
Croatian: 2 kapsule ujutro i 2 kapsule navečer Vidjeti dozu za odrasle
English: Rebetol dose (mg/kg)
Croatian: Doza lijeka Rebetol (mg/kg)
English: Excipients with known effect Rebetol contains 142 mg of sorbitol and 300 mg of sucrose per mL.
Croatian: Pomoćne tvari s poznatim učinkom Rebetol sadrži 142 mg sorbitola i 300 mg saharoze po ml.
English: The ratio of whole blood:plasma ribavirin concentrations is approximately 60:1; the excess of ribavirin in whole blood exists as ribavirin nucleotides sequestered in erythrocytes.
Croatian: Omjer koncentracije ribavirina u krvi u odnosu na plazmu iznosi oko 60:1; postoji višak ribavirina u punoj krvi jer se nukleotidi ribavirina sekvestriraju u eritrocite.
English: The salient safety issue of Rebetol is haemolytic anaemia occurring within the first weeks of therapy.
Croatian: Najistaknutiji sigurnosni problem povezan s primjenom lijeka Rebetol je hemolitička anemija, koja se javlja tijekom prvih tjedana liječenja.
English: Date of first authorisation: 25 January 2005 Date of latest renewal: 23 April 2009
Croatian: Datum posljednje obnove: 23. travnja 2009.
English: Although data on approximately 300 prospectively followed pregnancies with paternal exposure to Rebetol have not shown an increased risk of malformation compared to the general population, nor any specific pattern of malformation, either male patients or their female partners of childbearing age must be advised to use an effective contraceptive during treatment with Rebetol and for seven months after treatment.
Croatian: Iako podaci prikupljeni prospektivnim praćenjem oko 300 trudnoća u kojima je otac primao Rebetol nisu pokazali povećan rizik od malformacija u usporedbi s općom populacijom niti ikakvu specifičnu vrstu malformacija, mora se savjetovati bolesnicima ili njihovim partnericama u reproduktivnoj dobi da koriste djelotvornu kontracepciju tijekom liječenja lijekom Rebetol i još 7 mjeseci nakon završetka liječenja.
English: 15 mg/kg/day as 2 divided doses (n = 17)
Croatian: Rebetol 15 mg/kg/dan u 2 podijeljene doze (n=17)
English: All patients were to be followed for 24 weeks post-treatment.
Croatian: Sve se bolesnike moralo pratiti 24 tjedna nakon završetka liječenja.
English: In the pivotal clinical efficacy trial, patients were instructed to take ribavirin with food to achieve the maximal plasma concentration of ribavirin.
Croatian: U pivotalnom kliničkom ispitivanju djelotvornosti, bolesnicima se savjetovalo da uzimaju ribavirin s hranom kako bi se postigle maksimalne koncentracije ribavirina u plazmi.
English: *AUC12 (ng.hr/mL) for Rebetol; AUC0-24 (IU.hr/mL) for interferon alfa-2b
Croatian: *AUC12 (ng.h/ml) za Rebetol; AUC0-24 (IU.h/ml) za interferon afa-2b
English: • have problems with your kidneys.
Croatian: • imate tegoba s bubrezima.
English: This medicine stops the multiplication of hepatitis C virus.
Croatian: Ovaj lijek zaustavlja umnožavanje virusa hepatitisa C.
English: The plastic oral dosing syringe consists of two parts, an opaque barrel, and a white plunger rod that fits into the barrel.
Croatian: Plastična štrcaljka za usta sastoji se od dva dijela, neprozirnog tijela i bijelog klipa koji ulazi u tijelo.
English: Taking all your medicine: Take or give the prescribed dose by mouth in the morning and evening, with a meal.
Croatian: Uzmite cijelu količinu lijeka: Propisanu dozu uzmite ili dajte bolesniku kroz usta, ujutro i navečer, uz obrok.
English: Pharmacologically, Rebetol increases phosphorylated metabolites of purine nucleosides in vitro.
Croatian: Farmakološki, Rebetol dovodi do porasta fosforiliranih metabolita purinskih nukleozida in vitro.
English: (%)) in previously untreated children and adolescents by genotype and treatment duration - All subjects n = 107 24 weeks
Croatian: (%)) u djece i adolescenata koji nisu bili prethodno liječeni, prema genotipu i trajanju liječenja - svi ispitanici n = 107 24 tjedna
English: Infections and infestations Very common:
Croatian: Infekcije i infestacije vrlo često:
English: Cardiac status must be assessed before start of therapy and monitored clinically during therapy; if any deterioration occurs, therapy must be stopped (see section 4.2).
Croatian: Srčani status mora se procijeniti prije početka liječenja i klinički pratiti tijekom liječenja; dođe li do bilo kakvog pogoršanja, liječenje se mora prekinuti (vidjeti dio 4.2).
English: Twenty-four % had bridging fibrosis or cirrhosis (Knodell 3/4).
Croatian: 24% bolesnika imalo je premoštavajuću fibrozu ili cirozu jetre (Knodell 3/4).
English: Do not use this medicine without advice of your doctor or pharmacist if you notice any change in the appearance of the solution.
Croatian: Nemojte koristiti ovaj lijek bez savjetovanja s liječnikom ili ljekarnikom ako primijetite bilo kakvu promjenu u izgledu otopine.
English: Sexual dysfunction (not specified)* General disorders and administration site conditions Very common:
Croatian: Seksualna disfunkcija (nije specificirano)* Opći poremećaji i reakcije na mjestu primjene vrlo često:
English: Among patients with undetectable HCV-RNA at the end of treatment, the relapse rate was 24 %.
Croatian: Među bolesnicima u kojih je na kraju liječenja HCV-RNK bio nemjerljiv, stopa relapsa bila je 24%.
English: This medicine is available in different pack sizes containing 84, 112, 140 or 168 capsules of 200 mg to be swallowed.
Croatian: Ovaj lijek je dostupan u različitim veličinama pakiranja koja sadrže 84, 112, 140 ili 168 kapsula od 200 mg, koje treba progutati.
English: Among 480 patients with > 2 log viral reduction but detectable virus at week 12, altogether 188 patients continued therapy.
Croatian: Od 480 bolesnika sa smanjenjem virusnog opterećenja za >2 log, ali još mjerljivim virusom u 12. tjednu, ukupno ih je 188 nastavilo liječenje.
English: There may be some further treatment limitations if you have or have not been previously treated for chronic hepatitis C infection.
Croatian: Mogu postojati i dodatna ograničenja za liječenje, ovisno o tome jeste li prethodno liječeni zbog kroničnog hepatitisa C ili niste.
English: All Genotypes
Croatian: Svi genotipovi
English: Ribavirin has been shown to produce high inter- and intra-subject pharmacokinetic variability following single oral doses (intrasubject variability of approximately 30 % for both AUC and Cmax), which may be due to extensive first pass metabolism and transfer within and beyond the blood compartment.
Croatian: Ribavirin iskazuje veliku interindividualnu i intraindividualnu farmakokinetičku varijabilnost nakon primjene jedne peroralne doze (intraindividualna varijabilnost iznosi približno 30% i za AUC i za Cmax), što može biti posljedica opsežnog metaboliziranja prilikom prvog prolaza i prijelaza unutar i izvan krvnog odjeljka.
English: (by Rebetol dose [mg/kg], genotype and viral load) HCV Genotype
Croatian: (prema dozi lijeka Rebetol [mg/kg], genotipu i virusnom opterećenju) HCV genotip
English: In clinical studies performed in this population, Rebetol was used in doses of 15 mg/kg/day (Table 1).
Croatian: U kliničkim ispitivanjima provedenima u ovoj populaciji Rebetol se primjenjivao u dozi od 15 mg/kg/dan (Tablica 1).
English: Dose modification for adults
Croatian: Prilagodba doze u odraslih
English: In addition, injection site disorders, pyrexia, anorexia, vomiting and emotional lability occurred more frequently in children and adolescents compared to adult patients.
Croatian: Osim toga, promjene na mjestu injekcije, pireksija, anoreksija, povraćanje i emocionalna labilnost javljali su se češće u djece i adolescenata nego u odraslih bolesnika.
English: Prior to initiation of treatment with Rebetol the physician must comprehensively inform both male and female patients of the teratogenic risk of Rebetol, the necessity of effective and continuous contraception, the possibility that contraceptive methods may fail and the possible consequences of pregnancy should it occur during or following treatment with Rebetol (see section 4.6).
Croatian: Prije početka liječenja lijekom Rebetol, liječnik mora i bolesnicima i bolesnicama detaljno objasniti teratogeni rizik primjene lijeka Rebetol, potrebu za učinkovitom i kontinuiranom kontracepcijom, mogućnost neuspjeha kontracepcijskih metoda i moguće posljedice trudnoće ako ona nastupi tijekom ili nakon liječenja lijekom Rebetol (vidjeti dio 4.6).
English: Therefore, it is recommended that renal function be evaluated in all patients prior to initiation of Rebetol.
Croatian: Stoga se preporučuje provjeriti funkciju bubrega u svih bolesnika prije početka liječenja lijekom Rebetol.
English: Genotype 1* By Week 4*** (n= 950) HCV-RNA negative
Croatian: Do 4. tjedna*** (n= 950) HCV-RNK negativna
English: Rebetol must be used in combination with other medicinal products (see section 5.1).
Croatian: Rebetol se mora primjenjivati u kombinaciji s drugim lijekovima (vidjeti dio 5.1).
English: This Package Leaflet contains information for the paediatric patient (child or adolescent, 3 through 17 years of age), or for his or her parent or caregiver.
Croatian: Ova Uputa o lijeku sadrži informacije za pedijatrijske bolesnike (djecu i adolescente u dobi od 3 do 17 godina), odnosno za njihove roditelje ili skrbnike.
English: Upon cessation of treatment, essentially total recovery from ribavirin-induced testicular toxicity occurred within one or two spermatogenic cycles (see section 4.6).
Croatian: Nakon prestanka liječenja dolazi do zapravo potpunog oporavka od testikularne toksičnosti izazvane ribavirinom unutar jednog ili dva ciklusa spermatogeneze (vidjeti dio 4.6).
English: Hold the syringe to your mouth and release the dose into your mouth (or the mouth of the patient you are caring for) by pushing in the rod.
Croatian: Prinesite štrcaljku ustima i pritiskom na klip uštrcajte dozu u usta (sebi ili bolesniku za kojeg skrbite).
English: However, as in younger patients, renal function must be determined prior to administration of Rebetol (see section 5.2).
Croatian: Međutim, jednako kao i u mlađih bolesnika, prije primjene lijeka Rebetol mora se utvrditi funkcija bubrega (vidjeti dio 5.2).
English: Decrease in mean height percentile at year 1 of long term follow-up was most prominent in prepubertal age children.
Croatian: Prosječno smanjenje na percentilnoj krivulji rasta nakon godinu dana dugoročnog praćenja bilo je najizraženije u djece pretpubertetske dobi.
English: These time points (treatment week 4 and treatment week 12) have been shown to be predictive for sustained response (Table 10).
Croatian: Pokazalo se da ove vremenske točke (4. i 12. tjedan liječenja) imaju prediktivnu vrijednost za trajan virološki odgovor (Tablica 10).
English: There does not appear to be a significant age-related effect on the pharmacokinetics of Rebetol.
Croatian: Čini se da dob nema značajnog utjecaja na farmakokinetiku lijeka Rebetol.
English: • are a male and your female partner is of childbearing age (see section “Pregnancy and breast-feeding”).
Croatian: • muškarac, a Vaša partnerica je u reproduktivnoj dobi (vidjeti dio "Trudnoća i dojenje").
English: Pharmacotherapeutic group: antivirals for systemic use, antivirals for treatment of HCV infections, ATC code: J05AP01.
Croatian: Farmakoterapijska skupina: pripravci za liječenje sustavnih virusnih infekcija, antivirotici za liječenje HCV infekcija, ATK oznaka J05AP01.
English: Anti-thyroid antibody positive Injury, poisoning and procedural complications Common:
Croatian: pozitivna antitiroidna protutijela Ozljede, trovanja i proceduralne komplikacije često:
English: Adult:  12 g/dL (females);  13 g/dL (males) Children and adolescents:  11 g/dL (females);  12 g/dL (males)
Croatian: Odrasli: 12 g/dl (djevojčice);  3 g/dl (dječaci) Djeca i adolescenti: 11 g/dl (djevojčice); 12 g/dl (dječaci)
English: - Teratogenicity: Significant teratogenic and/or embryocidal potential have been demonstrated for Rebetol in all animal species in which adequate studies have been conducted, occurring at doses as low as one twentieth of the recommended human dose (see section 5.3).
Croatian: - Teratogenost: Rebetol je pokazao značajan teratogeni i/ili embriocidni potencijal u svih životinjskih vrsta na kojima su provedena odgovarajuća ispitivanja, pri dozama koje su iznosile samo 1/20 doze koja se preporučuje u ljudi (vidjeti dio 5.3).
English: Adding treatment with an alpha interferon alone or in combination with ribavirin may increase the risk in this patient subset.
Croatian: Dodavanje liječenja alfa interferonom samim ili u kombinaciji s ribavirinom može povećati rizik u ovoj podskupini bolesnika.
English: Homicidal ideation*, mania*, mental status change
Croatian: Homicidalne misli*, manija*, promjena psihičkog stanja
English: In the HIV-positive population receiving an NRTI regimen, physicians should carefully monitor markers of mitochondrial toxicity and lactic acidosis when Rebetol is administered.
Croatian: U HIV-pozitivnoj populaciji koja prima režim s NRTI, liječnici moraju pažljivo nadzirati markere mitohondrijske toksičnosti i laktacidoze za vrijeme primjene lijeka Rebetol.
English: Name and address of the manufacturer responsible for batch release for the hard capsules
Croatian: Naziv i adresa proizvođača odgovornog za puštanje serije lijeka u promet za tvrde kapsule
English: Rebetol oral solution is administered orally in two divided doses (morning and evening) with food.
Croatian: Rebetol oralna otopina primjenjuje se peroralno u dvije podijeljene doze (ujutro i navečer), uz obrok.