FrancophonIA/ELRC3.0 huggingface dataset:
English: In case of insufficient relief or recurrence of symptoms, a second injection of Firazyr can be administered after 6 hours.
Croatian: U slučaju nedovoljnog povlačenja simptoma ili povratka simptoma, nakon 6 sati može se dati druga injekcija Firazyra.
English: For icatibant, no clinical data on exposed pregnancies are available.
Croatian: Nisu dostupni klinički podaci za izloženost ikatibantu tijekom trudnoće.
English: Firazyr 30 mg Icatibant sc
Croatian: Icatibant sc
English: Tranexamic acid
Croatian: Ikatibant Traneksamska kiselina
English: In both rats and dogs, repeated use of icatibant resulted in effects on reproductive organs.
Croatian: Opetovana primjena ikatibanta kod štakora i pasa imala je za posljedicu učinke na reproduktivne organe.
English: Repeated-dose studies of up to 6-months duration in rats and 9-months duration in dogs have been conducted.
Croatian: Provedena su ispitivanja s ponovljenim dozama u trajanju do 6 mjeseci kod štakora, odnosno
English: No more than 3 injections of Firazyr should be administered in a 24 hour period.
Croatian: U razdoblju od 24 sata ne bi trebalo dati više od 3 injekcije Firazyra.
English: Icatibant volume of distribution (Vss) is about 20-25 L. Plasma protein binding is 44%.
Croatian: Distribucija Volumen distribucije ikatibanta (Vss) iznosi oko20-25 L.
English: Median time to overall patient improvement, by physician (hours)
Croatian: Medijan vremena do sveukupnog poboljšanja stanja bolesnika, procjena liječnika (sati)
English: In the clinical trial, not more than 1 injection of Firazyr per HAE attack has been administered.
Croatian: U kliničkom ispitivanju nije primijenjeno više od 1 injekcije lijeka Firazyr po napadaju angioedema.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS SYRINGE LABEL
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE NALJEPNICA ŠTRCALJKE
English: How to use Firazyr
Croatian: Kako primjenjivati Firazyr
English: Change in Composite Investigator-Assessed Symptom Score at 2 hours
Croatian: Promjena u rezultatu kompozitne procjene simptoma od strane ispitivača nakon 2 sata
English: Pharmacokinetic drug interactions involving CYP450 are not expected (see section 5.2).
Croatian: Ne očekuju se farmakokinetičke interakcije koje uključuju CYP450 (vidjeti dio 5.2) Nije proučavana istodobna primjena Firazyra s inhibitorima angiotenzin konvertirajućeg enzima (ACE).
English: Change in Composite Subject-Assessed Symptom Score at 2 hours
Croatian: Promjena u rezultatu kompozitne procjene simptoma od strane ispitanika nakon 2 sata
English: Subcutaneous use Read the package leaflet before use For single use only
Croatian: Prije uporabe pročitajte uputu o lijeku Samo za jednokratnu uporabu
English: Pharmacotherapeutic group: Other haematological agents, drugs used to treat hereditary angioedema;
Croatian: Farmakoterapijska skupina: Ostali hematološki pripravci, lijekovi koji se koriste za liječenje nasljednog angioedema: ATK oznaka: B06AC02.
English: Firazyr may be self-administered or administered by a caregiver only after training in subcutaneous injection technique by a healthcare professional.
Croatian: Firazyr si bolesnik može davati samostalno ili mu ga može davati njegovatelj, ali samo nakon što je podučen pravilnoj tehnici davanja supkutanih injekcija od strane zdravstvenog radnika.
English: HAE manifests as intermittent attacks of subcutaneous and/or sub mucosal oedema involving the upper respiratory tract, the skin and the gastrointestinal tract.
Croatian: Nasljedni angioedem (HAE) manifestira se kao sporadični napadaji supkutanog i/ili submukoznog edema koji zahvaćaju gornje dišne puteve, kožu i probavni trakt.
English: Your doctor will tell you when it is safe for you to go home. After discussion with your doctor or nurse and after training in subcutaneous (under the skin) injection technique, you may be able to inject yourself with Firazyr or your caregiver may inject Firazyr for you when you have an HAE attack.
Croatian: Nakon razgovora s liječnikom ili medicinskom sestrom i nakon obuke iz tehnike davanja supkutane (potkožne) injekcije, moći ćete samostalno ubrizgati Firazyr ili to može učiniti
English: Hepatic and Renal Impairment Limited data suggest that icatibant exposure is not influenced by hepatic or renal impairment.
Croatian: Ograničeni podaci ukazuju na to da oštećenja funkcije jetre ili bubrega ne utječu na izloženost ikatibantu.
English: • Remove the needle from the needle cap by pulling the syringe.
Croatian: • Izvadite iglu iz kapice igle povlačenjem štrcaljke.
English: 5) Discard the pre-filled syringe and connector into the sharps container.
Croatian: 5) Bacite iskorištenu napunjenu štrcaljku i adapter u spremnik za oštre predmete.
English: 1) Remove the caps on each end of the connector.
Croatian: 1) Uklonite kapice s oba kraja adaptera.
English: How to store Firazyr
Croatian: Kako čuvati Firazyr
English: Solution for injection One pre-filled syringe One 25G needle
Croatian: Otopina za injekciju Jedna napunjena štrcaljka i jedna igla 25 G.
English: No dose adjustment is required in patients with hepatic impairment.
Croatian: Nije potrebna prilagodba doze kod bolesnika s oštećenjem funkcije bubrega.
English: Each ml of the solution contains 10 mg of icatibant.
Croatian: Svaki ml otopine sadržava 10 mg ikatibanta.
English: - The recommended dose of Firazyr is one injection of 1 ml up to a maximum of 3 ml based on body weight injected subcutaneously (under the skin) as soon as you develop symptoms of an angioedema attack (for example increased skin swelling, particularly affecting the face and neck, increasing tummy pain).
Croatian: Djeca i adolescenti u dobi od 2 do 17 godina - Preporučena doza lijeka Firazyr je jedna injekcija od 1 ml do najviše 3 ml na temelju tjelesne težine, ubrizgana supkutano (pod kožu) čim razvijete simptome napadaja angioedema (na primjer pojačano oticanje kože, naročito na licu i vratu, pojačana bol u trbuhu).
English: Acetic acid, glacial (for pH adjustment) Sodium hydroxide (for pH adjustment) Water for injections
Croatian: natrijev hidroksid (za podešavanje pH)
English: 61.5 Baseline VAS(mm)
Croatian: 61,5 Početna vrijednost VAS (mm)
English: Package Leaflet: Information for the user Firazyr 30 mg solution for injection pre-filled syringe
Croatian: Uputa o lijeku: Informacije za korisnika Firazyr 30 mg otopina za injekciju u napunjenoj štrcaljki ikatibant
English: Solution for injection
Croatian: voda za injekcije
English: - If you are allergic to icatibant, or any of the other ingredients of this medicine (listed in section 6).
Croatian: Što morate znati prije nego počnete primjenjivati Firazyr Nemojte primjenjivati Firazyr - Ako ste alergični na ikatibant ili bilo koji drugi sastojak ovog lijeka (naveden u dijelu 6).
English: Each pre-filled syringe contains 30 milligrams of icatibant (as acetate).
Croatian: Jedna napunjena štrcaljka sadržava 30 miligrama ikatibanta (u obliku ikatibantacetata).
English: Firazyr 30 mg solution for injection in pre-filled syringe
Croatian: Firazyr 30 mg otopina za injekciju u napunjenoj štrcaljki
English: Firazyr 30 mg solution for injection in pre-filled syringe Icatibant
Croatian: Firazyr 30 mg otopina za injekciju u napunjenoj štrcaljki ikatibant
English: Firazyr may be administered by a caregiver only after training in subcutaneous injection technique by a healthcare professional.
Croatian: Njegovatelj smije primjenjivati Firazyr samo nakon što ga je zdravstveni radnik podučio supkutanoj tehnici ubrizgavanja.
English: Time to Almost Complete Symptom Relief (hrs)
Croatian: Vrijeme do gotovo potpunog ublažavanja simptoma (sati)
English: 12.0 All episodes (N = 56)
Croatian: 12,0 Sve epizode (N = 56)
English: Hypodermic needle is included in the pack.
Croatian: Igla za potkožnu primjenu uključena je u pakiranje.
English: The clinical relevance of the adrenal gland findings is unknown.
Croatian: Nije poznata klinička važnost nalaza na nadbubrežnim žlijezdama.
English: Each pre-filled syringe of 3 ml contains icatibant acetate equivalent to 30 mg icatibant.
Croatian: Svaka napunjena štrcaljka od 3 ml sadržava ikatibantacetat koji odgovara količini od 30 mg ikatibanta.
English: The active substance is icatibant.
Croatian: Djelatna tvar je ikatibant.
English: 51 kg to 65 kg
Croatian: 51 kg do 65 kg
English: • Remove the pre-filled syringe from the tray.
Croatian: • Izvadite napunjenu štrcaljku iz pakiranja.
English: Median time to almost complete symptom relief (hours)
Croatian: Medijan do gotovo potpunog ublažavanja simptoma (sati)
English: Other Endpoints Time to Onset of Primary Symptom Relief (hrs)
Croatian: Drugi ishodi Vrijeme do početka ublažavanja primarnog simptoma (sati)
English: Firazyr is used for treating the symptoms of hereditary angioedema (HAE) in adults, adolescents and children aged 2 years and older.
Croatian: Firazyr se koristi za liječenje simptoma nasljednog (hereditarnog) angioedema (HAE) kod odraslih,
English: Table 2: Adverse reactions reported with icatibant
Croatian: Tablica 2: Nuspojave zabilježene kod primjene ikatibanta Klasifikacija organskih sustava
English: • Put down the pre-filled syringe after unscrewing the cap.
Croatian: • Odložite napunjenu štrcaljku nakon što ste odvrnuli kapicu.
English: 7.9 All episodes (N = 56)
Croatian: 7,9 Sve epizode (N = 56)
English: Time to InvestigatorAssessed Initial Visual Symptom Improvement (hrs)
Croatian: Vrijeme do poboljšanja početnog vizualnog simptoma procijenjeno od strane ispitivača (sati)
English: 26 kg to 40 kg
Croatian: 26 kg do 40 kg
English: 6.9 All episodes (N = 56)
Croatian: 6,9 Sve epizode (N = 56)
English: 12 kg to 25 kg
Croatian: 12 kg do 25 kg
English: If you get any side effects talk to your doctor.
Croatian: Ako primijetite bilo koju nuspojavu, obavijestite liječnika.
English: Urticaria
Croatian: Koprivnjača
English: Change in Composite VAS Score at 2 hrs after treatment
Croatian: Promjena u rezultatu kompozitne vizualne analogne skale (VAS) 2 sata nakon liječenja
English: 41 kg to 50 kg
Croatian: 41 kg do 50 kg
English: Stroke
Croatian: Ishod
English: The solution should be clear and colourless and free from visible particles.
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom Otopina treba biti bistra i bezbojna i bez vidljivih čestica.
English: Paediatric use
Croatian: Pedijatrijska primjena
English: Median time to onset of symptom relief (hours)
Croatian: Medijan vremena do početka ublažavanja simptoma (sati)
English: In the pivotal juvenile toxicity study in which sexually immature rats were treated daily with 3 mg/kg/day for 7 weeks, atrophy of testes and epididymides were observed; the observed microscopic findings were partially reversible.
Croatian: U pivotalnom ispitivanju toksičnosti kod mladunaca u kojima su spolno nezreli štakori dnevno primali 3 mg/kg/dan u razdoblju od 7 tjedana,
English: All adverse reactions from post-marketing experience are italicised.
Croatian: Sve nuspojave iz razdoblja nakon stavljanja lijeka u promet navedene su u kurzivu.
English: Time to Subject-Assessed Initial Symptom Improvement (hrs)
Croatian: Vrijeme do poboljšanja početnog simptoma procijenjeno od strane ispitanika (sati)
English: All episodes (N = 74)
Croatian: (N = 74)
English: Baseline VAS(mm)
Croatian: Početna vrijednost VAS (mm)
English: System Organ Class (incidence category)
Croatian: (kategorija incidencije)
English: Name and address of the manufacturer responsible for batch release
Croatian: PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET Naziv i adresa proizvođača odgovornog za puštanje serije lijeka u promet Shire Pharmaceuticals Ireland Limited
English: • Open the tray by peeling back the seal.
Croatian: • Otvorite pakiranje odvajanjem zaštitne folije.
English: 2a) Preparing the syringe for children and adolescents (2-17 years) weighing 65 kg or less 2b) Preparing the syringe and needle for injection (all patients) 3) Preparing the injection site
Croatian: 2a) Priprema štrcaljke za djecu i adolescente (2 -17 godina) s tjelesnom težinom do najviše 65 kg
English: If there is air in the graduated syringe:
Croatian: Ako je prisutan zrak u graduiranoj štrcaljki: • Okrenite spojene štrcaljke tako da je napunjena štrcaljka na vrhu
English: One pre-filled syringe and one 25G needle.
Croatian: Jedna igla 25 G
English: Contents of the pack and other information What Firazyr contains
Croatian: Moguće nuspojave Kako čuvati Firazyr Sadržaj pakiranja i druge informacije
English: EU/1/08/461/001 EU/1/08/461/002
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/08/461/002
English: METHOD AND ROUTE(S) OF ADMINISTRATION
Croatian: NAČIN I PUT(EVI) PRIMJENE LIJEKA Potkožna primjena
English: Where the dose is less than 30 mg (3 ml), the following equipment is required to extract the appropriate dose (see below): a) Firazyr pre-filled syringe (containing icatibant solution) b) Connector (adapter) c) 3 ml graduated syringe
Croatian: Kada je doza manja od 30 mg (3 ml), potreban je sljedeći pribor za uzimanje odgovarajuće doze (vidjeti u nastavku):
English: 4) Injecting the solution
Croatian: 4) Ubrizgavanje otopine
English: Reporting of side effects
Croatian: Rezultati djelotvornosti
English: Dizziness Headache
Croatian: Vaše bolesti.
English: - If your symptoms are not resolved following one self- or caregiver administered injection of Firazyr, you should seek medical advice regarding additional injections of Firazyr.
Croatian: Firazyra, trebate potražiti liječnički savjet u vezi s dodatnim injekcijama Firazyra.
English: Median time to regression of symptoms, by patient (hours)
Croatian: Medijan vremena do regresije simptoma,
English: Refer to the patient information leaflet for instructions for use.
Croatian: Za upute o uporabi pogledajte uputu o lijeku.
English: Primary Endpoint Time to Onset of Symptom Relief-- Composite VAS (hrs)
Croatian: Kompozitna vizualna analogna skala (VAS) (sati)
English: --1 Attenuated infectious bursal disease virus, strain 1052, live, 101.48 to 102.63 PU* per dose * PU: Potency Units
Croatian: --1 Oslabljeni virus zarazne bursalne bolesti, soj 1052, živi, 101.48 do 102.63 PU* po dozi * PU: Jedinice potencije
English: EU Number Invented name
Croatian: Izmišljeno ime
English: Immediate packaging
Croatian: Put primjene Unutarnjem pakovanju
English: Intravenous use vial (glass)
Croatian: Za primjenu u venu bočica (staklo)
English: 250 µg Solution for injection
Croatian: Otopina za injekciju
English: Immediate packaging Pack size
Croatian: Unutarnje pakovanje Veličina pakovanja
English: It has been authorised in 16 EU Member States.
Croatian: Odobren je u 16 država članica Europske unije.
English: Eggs were sampled twice daily.
Croatian: Jaja su uzorkovana dvaput na dan.
English: These were achieved at about 2-4 hours after dosing.
Croatian: To se postiže nakon otprilike 2 - 4 sata nakon doziranja.
English: No resistant strains were found.
Croatian: Nisu nađeni rezistentni sojevi.
English: Three distinct multi-resistant strains were isolated.
Croatian: Izolirana su tri različita multirezistentna soja.
English: The words “Keep out of the sight and reach of children” Keep out of the sight and reach of children.
Croatian: Riječi „Čuvati izvan pogleda i dosega djece“
English: Residues in eggs were well below the MRL at all time points.
Croatian: Rezidui u jajima bili su prilično ispod MRL-a u svim vremenskim točkama.
English: The dosage of the product to be incorporated should be established according to the following formula:
Croatian: Dozu proizvoda za primjenu treba izračunati prema sljedećoj formuli:
English: If you notice any side effects, even those not already listed in this label, or you think that the medicine has not worked, please inform your veterinary surgeon.
Croatian: Ako zamijetite bilo koju nuspojavu, čak i one koje nisu navedene u ovoj uputi o VMP ili mislite da veterinarsko-medicinski proizvod ne djeluje, molimo obavijestite svog veterinara.
English: Novartis Animal Health d.o.o.
Croatian: Novartis Animal Health d.o.o. Verovškova 57
English: The resistance situation for these pathogens is considered favourable.
Croatian: Za te patogene rezistencija se smatra povoljnom.
English: List of the names, pharmaceutical form, strength of the veterinary medicinal products, animal species, route of administration, marketing authorisation holders in the Member States
Croatian: Popis naziva, farmaceutskih oblika, jačina veterinarsko medicinskog proizvoda, vrsta životinja, puteva primjene, nositelja odobrenja za stavljanje u promet u državama članicama
English: Consequently, a withdrawal period in eggs of zero days is accepted.
Croatian: Posljedično tome, prihvaćeno je razdoblje karencije za jaja od nula dana.
English: Pigs were treated at the intended dose and sacrificed 24 hours, 3, 4, 5 and 6 days after last administration.
Croatian: Svinje su liječene namjeravanom dozom i žrtvovane 24 sata te 3, 4, 5 i 6 dana nakon posljednje primjene.
English: The MIC50 was considered high, but the isolates presented a wild-type susceptibility pattern suggesting lack of resistance.
Croatian: MIK50 smatrao se visokim, ali izolati su pokazivali obrazac divljeg tipa osjetljivosti, što je ukazivalo na manjak rezistencije.
English: Recent M. meleagridis-isolates are difficult to obtain as it was eradicated from most breeding flocks and only rarely occurs in the field.
Croatian: Novije izolate za M. meleagridis teško je dobiti, jer je iskorijenjena iz većine uzgojnih jata i samo se rijetko javlja na terenu.
English: It does not appear to have any adverse effect on overall performance of the birds or efficacy of the veterinary medicinal product but water intake should be monitored at frequent intervals, especially in hot weather.
Croatian: Čini se da nema negativnih učinaka na ukupno uspijevanje peradi ili djelotvornost veterinarsko-medicinskog proizvoda, ali unos vode treba često nadzirati, posebno tijekom vrućina.
English: The intake of medicated water depends on the clinical condition of the animals.
Croatian: Unos medicinirane vode ovisi o kliničkom stanju životinja.
English: In these studies doses were expressed as concentrations in drinking water.
Croatian: U ovim ispitivanjima doze su bile izražene kao koncentracije u vodi za piće.
English: Pregnancy and lactation: Can be used in pigs during pregnancy and lactation.
Croatian: Graviditet i laktacija: Može se primjenjivati kod svinja tijekom graviditeta i laktacije.
English: Elanco Europe Ltd.
Croatian: Češka Republika Elanco Europe Ltd.
English: Currently further isolates have been tested from Korea (Yeh et al., 2011)6, Brazil and from Thailand (MAH proprietary data, 2016).
Croatian: Dosad su testirani dodatni izolati iz Koreje (Yeh et al., 2011.)6, Brazila i Tajlanda (vlasnički podaci nositelja odobrenja, 2016.).
English: The actual doses in mg/kg body weight could only be estimated.
Croatian: Stvarne doze u mg/kg tjelesne težine mogle su se samo procijeniti.
English: To be completed nationally.
Croatian: Dopuniti na nacionalnoj razini.
English: ALUMINIUM LAMINATE BAG
Croatian: ALUMINIJSKA LAMINIRANA VREĆICA
English: The words “For animal treatment only” and conditions or restrictions regarding supply and use, if applicable
Croatian: Riječi „Samo za primjenu na životinjama“ i uvjeti ili ograničenja u pogledu opskrbe i primjene, ako je primjenjivo Samo za primjenu na životinjama.
English: The recommended harmonised indications and dosing regimens have not been extended and consequently the use of the product as recommended in the product information should not lead to increased exposure of the environment.
Croatian: Preporučene harmonizirane indikacije i režimi doziranja nisu bili proširivani pa, posljedično tome primjena lijeka kako se preporučuje u ne bi trebala dovoditi do povećanog izlaganja okoliša.
English: Name and address of the marketing authorisation holder and of the manufacturing authorisation holder responsible for batch release, if different
Croatian: Naziv i adresa nositelja odobrenja za stavljanje u promet i nositelja odobrenja za proizvodnju odgovornog za puštanje serije u promet, ako je različito
English: The withdrawal periods have been revised following assessment of the available residue depletion data to ensure consumer safety.
Croatian: Razdoblja karencije promijenjena su nakon procjene dostupnih podataka za depleciju rezidua kako bi se osigurala sigurnost potrošača.
English: If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of target bacteria.
Croatian: Ako to nije moguće, terapija se treba temeljiti na lokalnim (regionalna razina, razina farme) epidemiološkim informacijama o osjetljivosti ciljne bakterije.
English: A number of isolates in Korea and Thailand may have higher iMIC figures than previously reported in the EU and USA by Wattanaphansak et al. (2009).
Croatian: Nekoliko izolata iz Koreje i s Tajlanda možda ima više vrijednosti iMIK-a nego što su to za EU i SAD prethodno zabilježili Wattanaphansak et al. (2009.).
English: This suggests that reduced sensitivity of individual Lawsonia strains can occur but as there have been no reported adverse events in the EU regarding treatment of ileitis failures it suggests that such reduced sensitivity has not developed extensively in the EU.
Croatian: Lawsonia može pojaviti smanjena osjetljivost, ali kako u EU-u nisu zabilježeni štetni događaji s obzirom na neuspjela liječenja ileitisa, čini se da se takva smanjena osjetljivost nije naširoko razvila u EU-u.
English: The epidemiological cut-off value was considered at 16 µg/ml which corresponds to the current Clinical and Laboratory Standards Institute (CLSI) standard (S ≤16 µg/ml, R ≥32 µg/ml).
Croatian: Kao epidemiološka granična vrijednost smatrala se ona od 16 µg/ml, što odgovara sadašnjem standardu Instituta kliničkih i laboratorijskih standarda (Clinical and Laboratory Standards Institute, CLSI) (S ≤16 µg/ml, R ≥32 µg/ml).
English: Use of the product should be based on susceptibility testing of the bacteria isolated from the animal.
Croatian: Primjenu proizvoda treba temeljiti na testu osjetljivosti bakterija izoliranih iz životinje.
English: Based on the residue depletion data available the following withdrawal periods are recommended:
Croatian: Na temelju dostupnih podataka o depleciji rezidua preporučuju se sljedeća razdoblja karencije:
English: In case of exposure or accidental spillage onto skin the affected area should be washed with soap and water.
Croatian: U slučaju izloženosti ili prolijevanja proizvoda na kožu zahvaćeno područje treba oprati sapunom i vodom.
English: On 25 August 2015 Germany submitted a referral notification in accordance with Article 34(1) of Directive 2001/82/EC, to the CVMP/European Medicines Agency for Denagard 45% and its associated names (thereafter called Denagard 45%).
Croatian: Njemačka je 25. kolovoza 2015. u skladu s člankom 34. stavkom 1. Direktive 2001/82/EZ dostavila obavijest o arbitražnom postupku CVMP-u / Europskoj agenciji za lijekove za Denagard 45 % i povezane nazive (dalje u tekstu Denagard 45 %).
English: Inappropriate use of the veterinary medicinal product may increase the prevalence of bacteria resistant to tiamulin.
Croatian: Nepravilna primjena veterinarsko-medicinskog proizvoda može povećati prevalenciju bakterija otpornih na tiamulin.
English: Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Croatian: Bilo koji neupotrebljeni veterinarsko-medicinski proizvod ili otpadni materijali dobiveni primjenom veterinarsko-medicinskih proizvoda trebaju se odlagati u skladu s lokalnim propisima.
English: 2370 Arendonk Belgium
Croatian: Hoge Mauw 900 2370 Arendonk Belgium
English: Shelf life after first opening the immediate packaging: 3 months.
Croatian: Rok valjanosti poslije prvog otvaranja unutarnjeg pakovanja: 3 mjeseca.
English: Tiamulin has been shown to act at the 70S ribosome level and the primary binding sites are on the 50S subunit.
Croatian: Dokazano je da tiamulin djeluje na razini podjedinice ribosoma 70S, a primarne su točke vezivanja na podjedinici 50S.