FrancophonIA/ELRC3.0 huggingface dataset:
English: Older people There are no special precautions needed for the treatment of patients aged from 65 years and over.
Croatian: Nisu potrebne posebne mjere opreza tijekom liječenja bolesnika u dobi od 65 i više godina.
English: If you are at risk of gonorrhoea, ask your doctor or pharmacist for advice before using this medicine.
Croatian: Ako kod Vas postoji rizik od gonoreje, potražite savjet liječnika ili ljekarnika prije nego što primite ovaj lijek.
English: Your doctor will calculate this.
Croatian: Dozu će izračunati liječnik.
English: • serious allergic reaction which causes difficulty in breathing or dizziness (anaphylactic reaction),
Croatian: • ozbiljna alergijska reakcija koja uzrokuje otežano disanje ili omaglicu (anafilaktička reakcija),
English: The haemoglobin set-point was less than or equal to 9 g/dL in patients with symptoms and was less than or equal to 7 g/dL in patients without symptoms.
Croatian: Početna vrijednost hemoglobina bila je manja od ili jednaka 9 g/dl u bolesnika sa simptomima, a manja od ili jednaka 7 g/dl u bolesnika bez simptoma.
English: Efficacy outcomes for the pre-specified repeated measures analyses of the primary and secondary endpoints are provided in Table 10.
Croatian: Ishodi djelotvornosti analiza unaprijed određenih ponavljanih mjerenja primarnih i sekundarnih mjera ishoda prikazani su u tablici 10.
English: If you experience any of the meningococcal infection symptoms (see section 2 Meningococcal and other Neisseria infections alert), you should immediately inform your doctor.
Croatian: Ako osjetite bilo koji od simptoma meningokokne infekcije (pogledajte dio 2, Upozorenje zbog meningokokne i drugih infekcija uzrokovanih bakterijama roda Neisseria), morate odmah obavijestiti liječnika.
English: In 40 patients with PNH, a 1-compartmental model was used to estimate pharmacokinetic parameters after multiple doses.
Croatian: U 40 bolesnika s PNH-om, korišten je model s jednim odjeljkom za procjenu farmakokinetičkih parametara nakon višestrukih doza.
English: Additional serious medical complications occurred in these patients including severe worsening of kidney function, disease-related hospitalization and progression to end stage renal disease requiring dialysis.
Croatian: U tih bolesnika nastale su i dodatne ozbiljne medicinske komplikacije, uključujući teško pogoršanje funkcije bubrega, hospitalizaciju zbog bolesti i progresiju do završnog stadija bolesti bubrega koji zahtijeva dijalizu.
English: • menstrual disorder
Croatian: • menstrualni poremećaj
English: Soliris may be administered to patients aged 65 years and over.
Croatian: Soliris se može primijeniti u bolesnika u dobi od 65 godina i starijih.
English: Baseline characteristics are shown in Table 5.
Croatian: Početne značajke prikazane su u tablici 5.
English: In this setting, a decrease of the daily dose of at least 1 immunosuppressant was observed in 47% of patients.
Croatian: U tim okolnostima u 47% bolesnika opaženo je sniženje dnevne doze najmanje 1 imunosupresiva.
English: Note: Patients who did not experience an adjudicated On-trial Relapse were censored at the end of the Study Period.
Croatian: Napomena: Bolesnici koji prema neovisnoj procjeni nisu imali recidiv tijekom ispitivanja bili su cenzurirani na kraju razdoblja ispitivanja.
English: Please speak to your doctor before stopping Soliris.
Croatian: Obratite se liječniku prije nego što prestanete primati Soliris.
English: Discontinued treatment PRBC in previous 12 months (median (Q1,Q3))
Croatian: Transfuzija eritrocita u prethodnih 12 mjeseci (medijan (Q1,Q3))
English: Hypersensitivity to eculizumab, murine proteins or to any of the excipients listed in section 6.1.
Croatian: Preosjetljivost na ekulizumab, proteine miša ili neku od pomoćnih tvari navedenih u dijelu 6.1.
English: Therefore, an individual risk benefit analysis is recommended before starting and during treatment with eculizumab in pregnant women.
Croatian: Stoga se u trudnica preporučuje pojedinačna analiza koristi i rizika prije nego što se započne liječenje te tijekom liječenja ekulizumabom.
English: • spontaneous penile erection
Croatian: • spontana erekcija
English: Because of the study sample size and duration, the effects of Soliris on thrombotic events could not be determined.
Croatian: Zbog veličine uzorka i trajanja ispitivanja, učinci lijeka Soliris na trombotične incidente nisu se mogli utvrditi.
English: Patheon Italia S.p.A Viale G. B. Stucchi, 110 20900 Monza (MB) Italy
Croatian: Viale G. B. Stucchi, 110 20900 Monza (MB) Italija
English: After 3 weeks of Soliris treatment, patients reported less fatigue and improved health-related quality of life.
Croatian: 3 tjedna liječenja lijekom Soliris, bolesnici su rekli da su manje umorni i da im se poboljšala kvaliteta života vezana uz zdravlje.
English: Physicians should advise patients about gonorrhoea prevention.
Croatian: Liječnici moraju upoznati bolesnike s načinima prevencije gonoreje.
English: In Paroxysmal Nocturnal Haemoglobinuria (PNH):
Croatian: Kod paroksizmalne noćne hemoglobinurije (PNH):
English: Soliris should be prepared for administration by a qualified healthcare professional using aseptic technique.
Croatian: Soliris treba pripremiti za primjenu za to osposobljen zdravstveni radnik koristeći aseptičku tehniku.
English: The most common adverse reaction was headache, (occurred mostly in the initial phase of dosing), and the most serious adverse reaction was meningococcal sepsis.
Croatian: Najčešća nuspojava bila je glavobolja (koja se uglavnom javljala u početnoj fazi doziranja), a najozbiljnija nuspojava bila je meningokokna sepsa.
English: No specific adverse reactions have emerged from these clinical studies.
Croatian: U tim kliničkim ispitivanjima nisu se pojavile nikakve specifične nuspojave.
English: All patients should be monitored for early signs of meningococcal infection, evaluated immediately if infection is suspected, and treated with appropriate antibiotics if necessary.
Croatian: Sve bolesnike treba pratiti zbog ranih znakova meningokokne infekcije te ih odmah pregledati u slučaju sumnje na infekciju i, ako je potrebno, liječiti odgovarajućim antibioticima.
English: If you receive more Soliris than you should
Croatian: Ako primite više lijeka Soliris nego što ste trebali
English: Total number of patient-years in study period n
Croatian: Ukupni broj bolesnik-godina u razdoblju ispitivanja n
English: The most common adverse reaction reported in paediatric patients was headache.
Croatian: Najčešća nuspojava zabilježena u pedijatrijskih bolesnika bila je glavobolja.
English: Anticoagulant therapy Treatment with Soliris should not alter anticoagulant management.
Croatian: Liječenje lijekom Soliris ne bi trebalo promijeniti antikoagulantno liječenje.
English: Other medicines and Soliris Tell your doctor or pharmacist if you are using or have recently used or might use any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: 150 x 109/L despite PE/PI, and LDH and serum creatinine above upper limits of normal.
Croatian: 9/l usprkos PE/PI i vrijednostima LDH i kreatinina u serumu iznad gornje granice normale.
English: Soliris is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa.
Croatian: Soliris je građen od dva teška lanca s 448 aminokiselina i dva laka lanca od 214 aminokiselina te ima molekularnu masu od približno 148 kDa.
English: The patient should be monitored for one hour following infusion.
Croatian: Bolesnika treba nadzirati jedan sat nakon infuzije.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu/ .
Croatian: Detaljnije informacije o ovom lijeku dostupne su na internetskoj stranici Europske agencije za lijekove http://www.ema.europa.eu.
English: Patients should be monitored for one hour following infusion.
Croatian: Bolesnike treba nadzirati jedan sat nakon infuzije.
English: Due to its mechanism of action, the use of Soliris increases the patient's susceptibility to meningococcal infection (Neisseria meningitidis).
Croatian: Zbog njegovog mehanizma djelovanja, primjena lijeka Soliris povećava osjetljivost bolesnika na meningokoknu infekciju (Neisseria meningitidis).
English: The Soliris antibody contains human constant regions and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions.
Croatian: Protutijelo Soliris sadrži konstantne regije koje su ljudske, dok su regije koje određuju komplementarnost mišje i nasađene na ljudske varijabilne regije lakih i teških lanaca.
English: The median patient age was 35 (range: 18 to 80 years).
Croatian: Medijan dobi bolesnika iznosio je 35 godina (raspon: od 18 do 80 godina).
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton Label
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Označivanje na kutiji
English: • sudden and rapid development of extremely high blood pressure, low blood pressure, hot flush, vein disorder
Croatian: • iznenadni i brzi nastanak vrlo visokog krvnog tlaka, nizak krvni tlak, navale vrućine, poremećaj vena
English: You should take into consideration if you are on a controlled sodium diet.
Croatian: To trebate uzeti u obzir ako ste na dijeti s ograničenjem unosa natrija.
English: Must be diluted before use.
Croatian: Mora se razrijediti prije primjene.
English: When maternal exposure to the antibody occurred during organogenesis, two cases of retinal dysplasia and one case of umbilical hernia were observed among 230 offspring born to mothers exposed to the higher antibody dose (approximately 4 times the maximum recommended human Soliris dose, based on a body weight comparison); however, the exposure did not increase foetal loss or neonatal death.
Croatian: Kad je majka bila izložena protutijelu tijekom organogeneze, primijećena su dva slučaja retinalne displazije i jedan slučaj umbilikalne hernije u 230 potomaka majki izloženih višim dozama protutijela (približno 4 puta većima od maksimalne preporučene doze lijeka Soliris u ljudi, na temelju usporedbe tjelesne težine); međutim, izloženost nije povećala gubitak fetusa ili neonatalnu smrtnost.
English: After dilution, the product should be used within 24 hours.
Croatian: Nakon razrjeđivanja, lijek treba primijeniti u roku od 24 sata.
English: Based on the potential inhibitory effect of eculizumab on complement-dependent cytotoxicity of rituximab, eculizumab may reduce the expected pharmacodynamic effects of rituximab.
Croatian: Na temelju mogućeg inhibitornog učinka ekulizumaba na citotoksičnost rituksimaba ovisnu o komplementu, ekulizumab može smanjiti očekivane farmakodinamičke učinke rituksimaba.
English: 1- How is Soliris supplied?
Croatian: 1 - Kako se Soliris isporučuje?
English: The healthcare professionals should be advised to look for risk factors and signs and symptoms of Aspergillus infection.
Croatian: Zdravstvenim radnicima treba savjetovati da provjere postoje li čimbenici rizika i znakovi i simptomi infekcije plijesnima iz roda Aspergillus.
English: The median patient age was 6.5 years (range: 5 months to 17 years).
Croatian: Medijan dobi bolesnika iznosio je 6,5 godina (raspon: od 5 mjeseci do 17 godina).
English: What is Soliris
Croatian: Što je Soliris
English: Drug distribution will only be possible after written confirmation that the patient received or will receive meningococcal vaccination and/or antibiotic prophylaxis.
Croatian: 3. da će se lijek moći distribuirati samo nakon pismene potvrde da je bolesnik primio ili da će primiti meningokokno cjepivo i/ili antibiotsku profilaksu
English: Soliris is a clear and colorless solution.
Croatian: Soliris je bistra i bezbojna otopina.
English: Lonza Biologics Tuas Pte Ltd. 35 Tuas South Avenue 6
Croatian: Lonza Biologics Tuas Pte Ltd. 35 Tuas South Avenue 6 Singapur 637377
English: In the open-label extension trial (Study ECU-MG-302), physicians had the option to adjust background immunosuppressant therapies.
Croatian: U otvorenom produžetku ispitivanja (ispitivanje ECU-MG-302), liječnici su imali mogućnost prilagoditi osnovne terapije imunosupresivima.
English: The steady state is achieved by 4 weeks using the PNH adult dosing regimen.
Croatian: Stanje dinamičke ravnoteže postignuto je za 4 tjedna uz režim doziranja za odrasle s PNH-om.
English: The median duration of Soliris therapy was 16 weeks (range 4 to 70 weeks) for children < 2 years of age (n=5) and 31 weeks (range 19 to 63 weeks) for children 2 to <12 years of age (n=10).
Croatian: Medijan trajanja terapije lijekom Soliris iznosio je 16 tjedana (raspon od 4 do 70 tjedana) u djece dobi <2 godine (n = 5), i 31 tjedan (raspon od 19 do 63 tjedna) u djece u dobi od 2 do <12 godina (n = 10).
English: • pain in thejoints (arms and legs)
Croatian: • bol u zglobovima (ruke i noge)
English: The patient safety card should contain:
Croatian: U kartici za bolesnika sa sigurnosnim podacima mora biti navedeno sljedeće:
English: Figure 2: Kaplan-Meier Survival Estimates for Time to First Adjudicated On-Trial Relapse - Full Analysis Set
Croatian: Slika 2: Kaplan-Meierova procjena preživljenja u vremenu do pojave prvog recidiva u ispitivanju prema neovisnoj procjeni - potpuni skup za analizu
English: Severe TMA complications occurred in patients regardless of whether they had an identified genetic mutation, high risk polymorphism or auto-antibody.
Croatian: Teške komplikacije zbog TMA nastale su u bolesnika bez obzira na to jesu li imali utvrđenu genetsku mutaciju, visokorizični polimorfizam ili autoprotutijelo.
English: After dilution, the final concentration of the solution to be infused is 5 mg/ml.
Croatian: Nakon razrjeđivanja, konačna koncentracija otopine koja će se dati infuzijom je 5 mg/ml.
English: Refractory Generalized Myasthenia Gravis
Croatian: Refraktorna generalizirana miastenija gravis
English: Twenty-two (22) (17.6%) elderly refractory gMG patients (> 65 years of age) were treated with Soliris in the clinical trials.
Croatian: Dvadeset i dva bolesnika (17,6%) starije dobi (>65 godina) s refraktornim gMG-om bila su liječena Solirisom u kliničkim ispitivanjima.
English: • loss of appetite
Croatian: preosjetljivost • gubitak apetita
English: Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
Croatian: Unutar svake skupine po učestalosti, nuspojave su navedene u padajućem nizu prema ozbiljnosti.
English: 4.1 Therapeutic indication
Croatian: KLINIČKI PODACI 4.1 Terapijske indikacije
English: Additional endpoints included TMA intervention rate, haematologic normalization, complete TMA response, changes in LDH, renal function and quality of life.
Croatian: Dodatni ishodi uključivali su stopu intervencija zbog TMA, hematološku normalizaciju, potpuni TMA odgovor, promjene LDH, funkciju bubrega i kvalitetu života.
English: In a 26 week toxicity study performed in mice with a surrogate antibody directed against murine C5, treatment did not affect any of the toxicity parameters examined.
Croatian: U ispitivanju toksičnosti u trajanju od 26 tjedana provedenom u miševa sa zamjenskim protutijelom na mišji C5, liječenje nije utjecalo niti na jedan od ispitivanih parametara toksičnosti.
English: If you experience any of the following symptoms, you should immediately inform your doctor: - headache with nausea or vomiting - headache with a stiff neck or back - fever - rash - confusion - severe muscle aches combined with flu-like symptoms
Croatian: Ako osjetite neki od sljedećih simptoma, trebate o tome odmah obavijestiti svog liječnika: - glavobolja s mučninom ili povraćanjem - glavobolja s ukočenim vratom ili leđima - vrućica
English: There has been no observed correlation of antibody development to clinical response or adverse events.
Croatian: Nije opažena korelacija razvoja protutijela i kliničkog odgovora ili nuspojava.
English: Meningococcal disease due to any serogroup may occur.
Croatian: Meningokoknu bolest može izazvati bilo koja serološka skupina.
English: The dosing regimen in paediatric patients and adolescents weighing less than 40 kg was defined based on a pharmacokinetic (PK) simulation that identified the recommended dose and schedule based on body weight (see section 4.2).
Croatian: Režim doziranja u pedijatrijskih bolesnika i adolescenata tjelesne težine manje od 40 kg definiran je na temelju farmakokinetičke (PK) simulacije kojom su se utvrdili preporučena doza i raspored primjene na temelju tjelesne težine (vidjeti dio 4.2).
English: Animal reproduction studies have not been conducted with eculizumab due to lack of pharmacologic activity in non-human species.
Croatian: Nisu provedena ispitivanja utjecaja ekulizumaba na reprodukciju u životinja zbog nepostojanja farmakološke aktivnosti u drugih vrsta osim ljudi.
English: • The need to explain to and ensure understanding of by patients/carers: o the risks of treatment with eculizumab o the signs and symptoms of sepsis/severe infection and what action to take o the patient's/carer's guides and their contents o the need to carry the patient safety card and to tell any healthcare practitioner that he/she is receiving treatment with eculizumab o the requirement for vaccinations/antibiotic prophylaxis o the enrolment in the registries
Croatian: • Potreba da se bolesnicima/njegovateljima objasni i da se osigura da razumiju: o rizike liječenja ekulizumabom o znakove i simptome sepse/teške infekcije i što poduzeti o upute za bolesnike/njegovatelje i sadržaj tih uputa o potrebu da bolesnik sa sobom nosi karticu za bolesnika sa sigurnosnim podacima i da obavijesti svakog zdravstvenog radnika da prima terapiju ekulizumabom o zahtjev da budu cijepljeni/da uzimaju antibiotsku profilaksu o upis u registre.
English: • ringing in the ears, vertigo
Croatian: • zvonjenje u ušima, vrtoglavica
English: Chronic intravenous human immunoglobulin (IVIg) treatment may interfere with the endosomal neonatal Fc receptor (FcRn) recycling mechanism of monoclonal antibodies such as eculizumab and thereby decrease serum eculizumab concentrations.
Croatian: Kronično liječenje ljudskim imunoglobulinima za intravensku primjenu može ometati neonatalnim Fc receptorom (FcRn) posredovan endosomski mehanizam recikliranja monoklonskih protutijela poput ekulizumaba te tako smanjiti koncentracije ekulizumaba u serumu.
English: However, due to the limitations of the available data, the developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for eculizumab and any potential adverse effects on the breastfed child from eculizumab or from the underlying maternal condition.
Croatian: Međutim, zbog ograničenosti dostupnih podataka, potrebno je razmotriti i koristi dojenja na razvoj i zdravlje uz kliničku potrebu za liječenjem majke ekulizumabom te sve nuspojave koje se mogu pojaviti u dojenčadi zbog primjene ekulizumaba ili osnovne bolesti majke.
English: Soliris contains sodium
Croatian: Soliris sadrži natrij
English: Human antibodies undergo endocytotic digestion in the cells of the reticuloendothelial system.
Croatian: Humana protutijela se nakon endocitoze razgrađuju u stanicama retikuloendotelnog sustava.
English: Included Studies: Asthma (C07-002), aHUS(C08-002, C08-003, C10-003, C10-004), Dermatomyositis (C99-006), gMG (C08-001, ECU-MG-301, ECU-MG-302 data cut as of 31Dec2017), Neuromyelitis Optica Spectrum Disorder (ECU-NMO-301), IMG (C99-004, E99-004), PNH (C02-001, C04-001, C04-002, C06-002, C07-001, E02-001, E05001, E07-001, M07-005, X03-001, X03-001A), Psoriasis (C99-007), RA (C01-004, C97-001, C99-001, E01-004, E99-001), STEC-HUS (C11-001), SLE (C97-002).
Croatian: PNH (C02-001, C04-001, C04-002, C06-002, C07-001, E02-001, E05-001, E07-001, M07-005, X03-001, X03-001A), psorijaza (C99-007), RA (C01-004, C97-001, C99-001, E01-004, E99-001), STEC-HUS (C11-001),
English: Driving and using machines Soliris has no or negligible influence on the ability to drive and use machines.
Croatian: Upravljanje vozilima i strojevima Soliris ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Patients received meningococcal vaccination prior to receipt of Soliris.
Croatian: Bolesnici su primili meningokokno cjepivo prije primanja lijeka Soliris.
English: Pharmacokinetic Parameters
Croatian: Farmakokinetički parametri:
English: Body weight was a significant covariate resulting in a lower eculizumab clearance in pediatric patients requiring body weight based dosing in pediatric patients.
Croatian: Značajna kovarijata bila je tjelesna težina, pri čemu je rezultat bio manji klirens ekulizumaba u pedijatrijskih bolesnika što je zahtijevalo doziranje na temelju tjelesne težine u pedijatrijskih bolesnika.
English: 30 to <40 kg 600 mg weekly x 2 900 mg at week 3; then 900 mg every 2 weeks 20 to <30 kg 600 mg weekly x 2 600 mg at week 3; then 600 mg every 2 weeks 10 to <20 kg 600 mg weekly x 1 300 mg at week 2; then 300 mg every 2 weeks 5 to <10 kg 300 mg weekly x 1 300 mg at week 2; then 300 mg every 3 weeks
Croatian: 30 do <40 kg 600 mg tjedno x 2 900 mg u 3. tjednu; potom 900 mg svaka 2 tjedna 20 do <30 kg 600 mg tjedno x 2 600 mg u 3. tjednu; potom 600 mg svaka 2 tjedna 10 do <20 kg 600 mg tjedno x 1 300 mg u 2. tjednu; potom 300 mg svaka 2 tjedna 5 do <10 kg 300 mg tjedno x 1 300 mg u 2. tjednu; potom 300 mg svaka 3 tjedna
English: • yellowing of the skin and/or eyes (jaundice)
Croatian: • žuta boja kože i/ili bjeloočnica (žutica)
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation : 20 June 2007
Croatian: Datum prvog odobrenja: 20. lipnja 2007.
English: All rates of efficacy endpoints improved or were maintained through 2 years of treatment.
Croatian: U 2 godine liječenja sve stope ishoda djelotvornosti poboljšale su se ili održale.
English: 2 to <12 years (n=10)
Croatian: od 2 do <12 godina (n = 10)
English: Table 11 presents an overview of the patients reporting clinical deterioration and patients requiring rescue therapy over the 26 weeks.
Croatian: Tablica 11 prikazuje pregled bolesnika koji su prema vlastitoj procjeni imali kliničko pogoršanje i bolesnika kojima je bila potrebna simptomatska (engl. rescue) terapija tijekom 26 tjedana.
English: Patients that were previously treated with Soliris in Study ECU-MG-301 continued to demonstrate a sustained effect of Soliris on all measures (MG-ADL, QMG, MGC and MG-QoL15) over an additional 52 weeks of treatment with Soliris.
Croatian: Bolesnici koji su prije bili liječeni Solirisom u ispitivanju ECU-MG-301 nastavili su pokazivati održani učinak Solirisa u svim mjerama (MG-ADL, QMG, MGC i MG-QoL15) tijekom dodatna 52 tjedna liječenja Solirisom.
English: Data on a limited number of pregnancies exposed to eculizumab (less than 300 pregnancy outcomes) indicate there is no increased risk of foetal malformation or foetal-neonatal toxicity.
Croatian: Ograničeni podaci u trudnica (manje od 300 trudnoća) ukazuju da ekulizumab ne uzrokuje povećan rizik od malformacija ili feto/neonatalnih toksičnih učinaka.
English: Soliris is produced in a murine myeloma (NS0 cell line) expression system and purified by affinity and ion exchange chromatography.
Croatian: Soliris se proizvodi pomoću sustava ekspresije mišjeg mijeloma (stanična linija NS0) i pročišćava pomoću afinitetne kromatografije i kromatografije ionskom izmjenom.
English: Due to its mechanism of action, Soliris therapy should be administered with caution to patients with active systemic infections.
Croatian: Zbog njegovog mehanizma djelovanja, terapiju lijekom Soliris treba primijeniti s oprezom u bolesnika s aktivnim sistemskim infekcijama.
English: Serious haemolysis was not observed.
Croatian: Nije zabilježena pojava ozbiljne hemolize.
English: Because of the importance of rapidly identifying and treating certain types of infection in patients who receive Soliris, you will be provided a card to carry with you, listing specific trigger symptoms.
Croatian: Budući da je važno brzo postaviti dijagnozu i liječiti određene infekcije u bolesnika koji primaju Soliris, dobit ćete karticu koju morate nositi sa sobom i na kojoj su navedeni specifični početni simptomi.