FrancophonIA/ELRC3.0 huggingface dataset:
English: Treatment with Oncept IL-2 should begin the day before radiotherapy and preferably within one month of the removal of the tumour by surgery.
Danish: Behandlingen med Oncept IL-2 bør påbegyndes dagen før strålebehandling, fortrinsvis senest 1 måned efter, at tumoren er fjernet ved operation.
English: A course of treatment consists of six doses of 1 ml, the first four given at intervals of one week, and the last two at two-week intervals.
Danish: Heraf gives de første fire doser med en uges mellemrum, og de sidste to med to ugers mellemrum.
English: Side effects that may be seen with Oncept IL-2 treatment are short lived apathy (lack of responsiveness) and hyperthermia (increased body temperature above 39.5 °C from the normal value of 38 - 38.5 °C).
Danish: Behandlingen med Oncept IL-2 kan give bivirkninger i form af kortvarig sløvhed og temperaturforhøjelse (over 39,5 °C, sammenholdt med normalværdien på 38-38,5 °C).
English: Feline interleukin-2 recombinant canary pox virus
Danish: Felint interleukin-2 rekombinant canarypox virus
English: Oncept IL-2 was studied in two field studies involving 71 cats which had spontaneously developed fibrosarcoma that had not spread to other parts of the body.
Danish: Oncept IL-2 blev undersøgt i to feltundersøgelser med 71 katte, der spontant havde udviklet fibrosarkom, som ikke havde bredt sig til andre dele af kroppen.
English: The two studies compared a total of 48 cats treated with Oncept IL-2 with 23 control cats that just received surgery and radiotherapy.
Danish: I de to undersøgelser blev 48 katte, der var behandlet med Oncept IL-2, sammenlignet med 23 kontrolkatte, der netop var blevet opereret og havde fået strålebehandling.
English: A moderate reaction at the injection site may occur that involves signs of pain when the area is touched, swelling and scratching.
Danish: På injektionsstedet kan der komme en moderat reaktion med berøringsømhed, hævelse og kløe.
English: Oncept-IL2 is produced by a method known as ‘recombinant DNA technology': it contains viruses that have received a gene (DNA), which makes them able to produce IL-2.
Danish: Oncept-IL2 fremstilles ved “rekombinant DNA-teknologi”: Det indeholder virus, der har fået indsat et gen (DNA), som gør det i stand til at producere IL-2.
English: Oncept IL-2 is used to treat cats with fibrosarcoma, a type of aggressive tumour which affects the soft tissues.
Danish: Oncept IL-2 anvendes til behandling af katte med fibrosarkom, en aggressiv tumortype, der angriber det bløde væv.
English: Other information about Oncept IL-2:
Danish: Andre oplysninger om Oncept IL-2:
English: Oncept IL-2 is a veterinary medicine that contains the active substance feline interleukin-2 recombinant canarypox virus (vCP1338).
Danish: Oncept IL-2 er veterinærlægemiddel, der indeholder det aktive stof felint interleukin-2 rekombinant canarypox virus (vCP1338).
English: The active substance in Oncept IL-2 is a ‘carrier' canarypox virus that contains the gene to produce the protein feline interleukin-2 (IL-2).
Danish: Det aktive stof i Oncept IL-2 er et canarypox “bærervirus”, der indeholder genet til dannelse af proteinet felint interleukin-2 (IL-2).
English: What is the risk associated with Oncept IL-2?
Danish: Hvilken risiko er der forbundet med Oncept IL-2?
English: Oncept-IL2 is an immunomodulating agent, which means that it affects the activity of the immune system (the body's natural defences).
Danish: Det vil sige, at det påvirker aktiviteten af immunsystemet (kroppens naturlige forsvar).
English: Why has Oncept IL-2 been approved?
Danish: Hvorfor blev Oncept IL-2 godkendt?
English: It is available as a lyophilisate (freeze dried pellet) and solvent (water for injections) that are made up into a suspension for injection.
Danish: Oncept IL-2 er et lyofilisat (en frysetørret pellet) med opløsningsvæske (vand til injektionsvæske), der benyttes til at fremstille en suspension til injektion.
English: What is Oncept IL-2?
Danish: Hvad er Oncept IL-2?
English: How has Oncept IL-2 been studied?
Danish: Hvordan blev Oncept IL-2 undersøgt?
English: What benefit has Oncept IL-2 shown during the studies?
Danish: Hvilken fordel viser undersøgelserne, at der er ved Oncept IL-2?
English: How does Oncept IL-2 work?
Danish: Hvordan virker Oncept IL-2 ?
English: What is Oncept IL-2 used for?
Danish: Hvad anvendes Oncept IL-2 til?
English: The product is intended for:
Danish: Produktet er beregnet til:
English: The product is not intended for repeat injections.
Danish: Dette produkt er ikke beregnet til gentagne injektioner.
English: Frequent and regular monitoring of respiratory and cardiac function should be performed.
Danish: Hyppig og regelmæssig overvågen af åndedræts- og hjertefunktion skal foretages.
English: In a clinical study, the requirement for propofol was reduced by 50%.
Danish: I en klinisk undersøgelse blev behovet for propofol reduceret med 50%.
English: The Marketing Authorisation Holder must ensure that the system of pharmacovigilance, as described in Part 1 of the marketing authorisation application, is in place and functioning before and whilst the veterinary medicinal product is on the market.
Danish: Indehaveren af markedsføringstilladelsen skal sikre, at det lægemiddelovervågningssystem, som er beskrevet i Part I i ansøgningen om markedsføringstilladelse, er på plads og fungerer før og under markedsføringen af lægemidlet.
English: Pulse oximetry may be useful but is not essential for adequate monitoring.
Danish: Pulsoximetri kan være nyttig men er ikke nødvendig for tilstrækkelig overvågning.
English: After treatment, the animal should not be given water or food before it is able to swallow.
Danish: Efter behandling bør dyret ikke tilbydes foder eller vand, før det er i stand til at synke.
English: In a clinical study, the requirement for propofol and thiopental was reduced by 30% and 60% respectively.
Danish: I en klinisk undersøgelse blev behovet for propofol og tiopental reduceret med henholdsvis 30% og 60%.
English: STATEMENT OF ACTIVE AND OTHER SUBSTANCES 1 ml contains:
Danish: ANGIVELSE AF AKTIVE STOFFER OG ANDRE STOFFER 1 ml indeholder:
English: Corneal opacities may occur during sedation (see also section 4.5).
Danish: Der kan forekomme cornea-uklarhed hos katte under sedationen (se også afsnit4.5).
English: After withdrawal of the first dose, the product may be stored for 3 months at 25ºC.
Danish: Efter den første dosering må produktet maksimalt opbevares i 3 måneder ved 25ºC.
English: SPECIAL STORAGE CONDITIONS Do not freeze.
Danish: SÆRLIGE OPBEVARINGSBETINGELSER Må ikke nedfryses.
English: Do not use after the expiry date stated on the label and carton after EXP.
Danish: Må ikke anvendes efter den udløbsdato, som er angivet på etiketten og æsken efter UDL.D.
English: Respiration rate can occasionally decrease.
Danish: Respirations frekvensen kan lejlighedsvis blive nedsat.
English: Dosage: the following doses are recommended:
Danish: Dosering: Følgende doser anbefales:
English: THE WORDS “KEEP OUT OF THE SIGHT AND REACH OF CHILDREN” Keep out of the sight and reach of children.
Danish: TEKSTEN “OPBEVARES UDE AF SYNE OG UTILGÆNGELIGT FOR BØRN” Opbevares ude af syne og utilgængeligt for børn.
English: Shelf life after first opening: 3 months at 25°C.
Danish: Opbevaringstid efter åbning: 3 måneder ved 25°C.
English: The apparent volume of distribution (Vd) is 2.2 L/kg and the elimination half-life (t½) is one hour.
Danish: Fordelingsvolumet (Vd) er 2,2 L/kg, og eliminationshalveringstiden (t½) er en time.
English: Metabolites are excreted mainly in the urine (51% of the dose), and to a lesser extent in the faeces.
Danish: Metabolitterne udskilles for det meste i urinen (51% af dosen) og i mindre grad i afføringen.
English: The mean half-life of elimination of dexmedetomidine increased to 1.6 h and the total exposure (AUC) increased by 50%.
Danish: Middelhalveringstiden af dexmedetomidin steg til 1,6 t og den totale eksponering (AUC) blev øget med 50 %.
English: Water may be given.
Danish: Dyret må gerne få vand.
English: Brady- and tachyarrhythmias have been reported.
Danish: Der er blevet rapporteret brady- og tachyarytmi.
English: In a clinical study, dexmedetomidine contributed to postoperative analgesia for 0.5 - 4 hours.
Danish: I en klinisk undersøgelse bevirkede dexmedetomidin postoperativ analgesi i 0,5 - 4 timer.
English: Vetoquinol UK Limited Steadings Barn, Pury Hill Business Park Nr Alderton, Towcester Northants, NN12 7LS
Danish: Vetoquinol UK Limited Steadings Barn Pury Hill Business Park Nr Alderton, Towcester Northans, NN12 7LS
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS/ MULTI PACKAGE
Danish: MINDSTEKRAV TIL OPLYSNINGER PÅ SMÅ INDRE PAKNINGER / MULTIPAKKE HÆTTEGLAS / MULTIPAKKE
English: Dexdomitor contains dexmedetomidine as the active substance, which produces sedation and analgesia in dogs and cats.
Danish: Dexdomitor indeholder dexmedetomidin som det aktive stof, der frembringer sedation og analgesi hos hunde og katte.
English: Pharmacotherapeutic group: psycholeptic, ATCvet code: QN05CM18.
Danish: Farmakoterapeutisk gruppe: Psykoleptisk, ATCvet-kode: QN05CM18.
English: Cats: The maximum plasma concentration is reached about 0.24 h after intramuscular administration.
Danish: Katte: Den maksimale plasmakoncentration nås på ca. 0,24 timer efter intramuskulær indgivelse.
English: THE WORDS “FOR ANIMAL TREATMENT ONLY” AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE, IF APPLICABLE
Danish: TEKSTEN “KUN TIL DYR” SAMT BETINGELSER ELLER BEGRÆNSNINGER
English: In clinical trials the incidence of hypoxaemia was common, especially within the 15 first minutes into dexmedetomidine-ketamine anaesthesia.
Danish: I kliniske studier var hypoxæmi almindeligt forekommende, især indenfor de første 15 minutter efter påbegyndt dexmedetomidin-ketamin anæstesi.
English: The administration of dexmedetomidine to puppies younger than 16 weeks and kittens younger than 12 weeks has not been studied.
Danish: Anvendelse af dexmedetomidin til hvalpe under 16 uger eller killinger under 12 uger er ikke blevet undersøgt.
English: For information on target animal safety in cases of overdosing, see section 4.10.Overdose
Danish: Yderligere oplysninger om sikkerhed i tilfælde af overdosering hos de behandlede dyr findes under afsnit 4.10: Overdosering.
English: EXPIRY DATE EXP: month/year
Danish: UDL.D: måned/år
English: In some dogs and cats a decrease in respiratory rate may occur.
Danish: Hos nogle hunde og katte kan der forekomme en nedsættelse af respirationsfrekvensen.
English: If pregnant women handle the product, special caution should be observed not to self-inject as uterine contractions and decreased foetal blood pressure may occur after accidental systemic exposure.
Danish: Gravide kvinder skal under håndtering af produktet udvise særlig forsigtighed for at undgå selvindsprøjtning, idet kontraktioner af uterus og fald i fostrets blodtryk kan opstå efter en systemisk eksponering.
English: Administration of atipamezole after dexmedetomidine rapidly reverses the effects and thus shortens the recovery period.
Danish: Indgivelse af atipamezol efter dexmedetomidin ophæver hurtigt virkningen og forkorter på den måde opvågningstiden.
English: DOGS:
Danish: HUNDE:
English: Attention should be given during the administration of intravenous induction drugs to effect.
Danish: Der bør udvises særlig opmærksomhed under indgivelse af intravenøs induktionsmedicin til effekt.
English: Within 15 minutes dogs and cats are normally awake and standing.
Danish: Hundene og kattene er normalt vågne og står op inden for 15 minutter.
English: In the circulation, dexmedetomidine is largely bound to plasma proteins (>90%).
Danish: I kredsløbet binder dexmedetomidin sig for det meste til hundens og kattens plasmaproteiner (>90%).
English: Dexdomitor is compatible with butorphanol and ketamine in the same syringe at least for two hours.
Danish: Dexdomitor er kompatibelt med butorphanol og ketamin i den samme sprøjte i mindst to timer.
English: Dexmedetomidine also induces a number of other α2adrenoceptor mediated effects, which include piloerection, depression of motor and secretory functions of the gastrointestinal tract, diuresis and hyperglycaemia.
Danish: Dexmedetomidin inducerer ligeledes en række andre α-2 adrenoceptor-medierede virkninger, der omfatter hårrejsning, depression af motoriske og sekretoriske funktioner i gastrointestinalkanalen, diurese og hyperglykæmi.
English: The premedication dose of dexmedetomidine is 125 - 375 micrograms/square metre body surface area, administered 20 minutes prior to induction for procedures requiring anaesthesia.
Danish: Dosis af dexmedetomidin ved præmedicinering er 125 - 375 mikrogram pr. kvadratmeter legemsoverflade, som indgives 20 minutter inden induktion ved anæstesikrævende procedurer.
English: The bioavailability of dexmedetomidine is 60% and the apparent volume of distribution (Vd) is 0.9 L/kg.
Danish: Biotilgængeligheden af dexmedetomidin er 60%, og den fordelings volumen (Vd) er 0,9 L/kg.
English: Do not use in case of known hypersensitivity to the active substance or to any of the excipients.
Danish: Bør ikke anvendes i tilfælde af overfølsomhed over for det aktive stof eller et eller flere af hjælpestofferne.
English: Equipment for manual ventilation should be available in case of respiratory depression or apnoea when dexmedetomidine and ketamine are used sequentially to induce anaesthesia in cats.
Danish: Udstyr til manuel ventilation skal være tilgængeligt, hvis depression af åndedrættet eller apnø skulle opstå når dexmedetomidin og ketamin gives efter hinanden til at bedøve katte.
English: Dexmedetomidine doses are based on body surface area:
Danish: Dexmedetomidindoser til hunde er baseret på deres legemsoverflade:
English: CATS:
Danish: Katte:
English: Persons with known hypersensitivity to the active substance or any of the excipients should administer the product with caution.
Danish: Personer med overfølsomhed over for produktets aktive stof eller hjælpestoffer bør udvise forsigtighed i forbindelse med indgivelse af stoffet.
English: At high serum concentration of dexmedetomidine sedation is not increased although the level of analgesia does increase with further dose increases.
Danish: Ved en høj serumkoncentration af dexmedetomidin øges sedationen ikke, selvom analgesiniveauet forøges med flere forøgelser af dosen.
English: At high serum concentrations of dexmedetomidine sedation is not increased although the level of analgesia does increase with further dose increases.
Danish: Ved høje serumkoncentrationer af dexmedetomidin, øges sedationen ikke, selvom der analgesiniveauet forøges med flere forøgelser af dosen.
English: Sintra Business Park, Nº7, Edifício 1 - Escritório 2K Zona Industrial de Abrunheira 2710-089 Sintra
Danish: Sintra Business Park, Nº7, Edifício 1 - Escritório 2K
English: PHARMACEUTICAL FORM Solution for injection Clear, colourless solution
Danish: LÆGEMIDDELFORM Injektionsvæske, opløsning Klar, farveløs opløsning
English: List of excipients:
Danish: Liste over hjælpestoffer:
English: After concurrent exposure to a triple (3X) overdose of dexmedetomidine and 15 mg ketamine/ kg, atipamezole can be administered at the recommended dose level for reversal of effects induced by dexmedetomidine.
Danish: Efter samtidig udsættelse for en tredobbelt (3x) overdosis dexmedetomidin og 15 mg ketamin pr. kg legemsvægt kan der administreres den anbefalede mængde atipamezol for at ophæve de bivirkninger, der er forårsaget af dexmedetomidinen.
English: Dexdomitor, butorphanol and/or ketamine can be mixed in the same syringe as they have been shown to be pharmacologically compatible.
Danish: Dexdomitor, butorphanol og/eller ketamin can blandes i den samme sprøjte, da de er vist at være pharmakologisk forenelige.
English: After a 40 micrograms/kg bw intramuscular dose the Cmax is 17 ng/ml.
Danish: Efter en 40 mikrogram/kg legemsvægt intramuskulær dosis er Cmax 17 ng/ml.
English: ROUTE(S) OF ADMINISTRATION Dogs: IM, IV
Danish: INDGIVELSESVEJ(E) Hunde: i.v., i.m.
English: After a 40 micrograms/kg bw intramuscular dose the Cmax is 17 nanograms/ml.
Danish: Efter en 40 mikrogram/kg legemsvægt intramuskulær dosis er Cmax 17 nanogram/ml.
English: In cases of overdosing the following recommendations should be followed:
Danish: Følg følgende anvisninger i tilfælde af overdosering:
English: Dogs: After an intramuscular dose of 50 micrograms/kg a maximum concentration in plasma of about 12 nanograms/ml is reached after 0.6 hours.
Danish: Hunde: Efter en intramuskulær dosis på 50 mikrogram/kg nås maksimumkoncentrationen i plasma på ca. 12-nanogram/ml i løbet af 0,6 timer.
English: In cats, corneal opacities may occur during sedation.
Danish: Der kan forekomme cornea-uklarhed hos katte under sedationen.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/02/033/003
Danish: MARKEDSFØRINGSTILLADELSENS NUMMER (NUMRE) EU/2/02/033/003
English: When dexmedetomidine and ketamine are used sequentially, with a 10 minute interval, cats may occasionally experience AV-block or extrasystole.
Danish: Når dexmedetomidin og ketamin gives efter hinanden med 10 minutters interval, kan der lejlighedsvis forekomme av-blok eller ekstrasystole hos katte.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/02/033/003-004
Danish: MARKEDSFØRINGSTILLADELSENS NUMMER (NUMRE) EU/2/02/033/003-004
English: MARKETING AUTHORISATION NUMBER(S) EU/2/02/033/001-002
Danish: MARKEDSFØRINGSTILLADELSENS NUMMER (NUMRE) EU/2/02/033/001-002
English: The peak sedative and analgesic effects are reached within 30 minutes after administration.
Danish: Den sedative og analgetiske virkning topper indenfor 30 minutter efter indgivelse.
English: Dogs: After an intramuscular dose of 50 micrograms/kg a maximum concentration in plasma of about 12 ng/ml is reached after 0.6 hours.
Danish: Hunde: Efter en intramuskulær dosis på 50 mikrogram/kg nås maksimumkoncentrationen i plasma på ca. 12 ng/ml i løbet af 0,6 timer.
English: It is recommended that animals are fasted for 12 hours prior to Dexdomitor administration.
Danish: Det anbefales, at dyret bliver fastet i 12 timer inden anvendelsen af dexmedetomidin.
English: Anaesthesia can be induced 10 minutes after premedication by intramuscular administration of a target dose of 5 mg ketamine/kg bw or by intravenous administration of propofol to effect.
Danish: Bedøvelsen kan foretages 10 minutter efter præmedicinering via intramuskulær indsprøjtning af en ketamindosis på 5 mg/kg legemsvægt eller ved intravenøs administration af propofol til effekt.
English: Keep out of the sight and reach of children.
Danish: Opbevares ude af syne og utilgængeligt for børn.
English: Concomitant use of dexmedetomidine and butorphanol produces sedative and analgesic effects beginning no later than 15 minutes.
Danish: Samtidig brug af dexmedetomidin og butorphanol medfører sedation og analgesi senest 15 minutter efter indgivelse.
English: The specific α2 -adrenoceptor antagonist, atipamezole, which is approved for use in animals, has been used in humans only experimentally to antagonize dexmedetomidine-induced effects.
Danish: Den specifikke α2 -adrenoceptor-antagonist, atipamezol, som er godkendt til brug hos dyr, er kun blevet anvendt eksperimentelt hos mennesker til at ophæve virkningen af dexmedetomidininducerede virkninger.
English: 6.5 Nature and composition of immediate packaging Cardboard box with 1 glass (Type I) vial of 20 ml (with filling volume of 15 ml) with a bromobutyl rubber stopper and aluminium cap.
Danish: Papæske med et 20 ml hætteglas (Type I) (med en fyldningsvolumen på 15 ml) med en bromobutylgummiprop og aluminiumhætte.
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) 0.5 mg/ml dexmedetomidine hydrochloride
Danish: MÆNGDEN AF AKTIVT STOF (AKTIVE STOFFER) 0,5 mg/ml dexmedetomidinhydrochlorid
English: When dexmedetomidine is used as a premedicant in dogs, bradypnoea, tachypnoea and vomiting may occur.
Danish: Når dexmedetomidin bruges til præmedicinering hos hunde, kan der opstå bradypnø, takypnø og opkastning.
English: When dexmedetomidine and butorphanol are used concomitantly in dogs, bradypnoea, tachypnoea, an irregular respiratory pattern (20-30 sec apnoea followed by several rapid breaths), hypoxaemia, muscle twitch or tremor or paddling, excitation, hypersalivation, retching, vomiting, urination, skin erythema, a sudden arousal, or prolonged sedation may occur.
Danish: Når dexmedetomidin og butorphanol anvendes samtidigt hos hunde, kan der forekomme bradypnø, tachypnoea, uregelmæssige åndedrætsrytmer (20-30 sek. apnø efterfulgt af flere hurtige åndedrag), hypoxæmi, muskelspjæt, -rysten eller andre muskelbevægelser, irritation, øget spytafsondring, kløgning, opkastning, urinering, huderytem, pludselig agitation eller forlænget sedation.
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) 0.1 mg/ml dexmedetomidine hydrochloride
Danish: MÆNGDEN AF AKTIVT STOF (AKTIVE STOFFER) 0,1 mg/ml dexmedetomidinhydrochlorid
English: For information on adverse reactions, see section 4.6.Adverse reactions.
Danish: Yderligere oplysninger om bivirkninger findes under afsnit 4.6: Bivirkninger.
English: Use of dexmedetomidine as a premedicant in dogs and cats significantly reduces the amount of induction drug required for induction of anaesthesia.
Danish: Brug af dexmedetomidin til præmedicinering hos hunde og katte reducerer den mængde induktionsmedicin, der er nødvendig ved induktion af anæstesi, væsentligt.
English: Propyl parahydroxybenzoate (E 216)
Danish: Propylparahydroxybenzoat (E 216)
English: Cats: After administration of 40 micrograms dexmedetomidine/ kg bw intramuscularly concurrently with 5 mg ketamine /kg bw to cats, the maximum concentration of dexmedetomidine increased twofold but there was no effect on T max.
Danish: Katte: Efter indgivelse af 40 microgram dexmedetomidin/ kg legemsvægt intramuskulært samtidigt med 5 mg ketamin /kg legemsvægt til katte, fordobles maksimum koncentrationen af dexmedetomidin, men Tmax påvirkes ikke deraf.
English: In case of accidental oral intake or self-injection, seek medical advice immediately and show the package insert to the physician but DO NOT DRIVE as sedation and changes in blood pressure may occur.
Danish: I tilfælde af uagtsom oral indtagelse eller selvinjektion skal der straks søges lægehjælp og indlægssedlen bør vises til lægen.
English: The safety of dexmedetomidine has not been established in males intended for breeding.
Danish: Lægemidletssikkerhed er ikke fastlagt hos hanner, som skal bruges til avl.
English: Use of dexmedetomidine as a premedicant in dogs significantly reduces the amount of induction drug required for induction of anaesthesia.
Danish: Brug af dexmedetomidin til præmedicinering hos hunde reducerer den mængde induktionsmedicin, der er nødvendig ved induktion af anæstesi, væsentligt.
English: For higher weight ranges, use DEXDOMITOR 0.5 mg/ml and its dosing tables.
Danish: Til større katte anvendes DEXDOMITOR 0,5 mg/ml og dets doseringstabeller.
English: ADVICE ON CORRECT ADMINISTRATION It is recommended that animals are fasted for 12 hours prior to administration.
Danish: OPLYSNINGER OM KORREKT ANVENDELSE Det anbefales, at dyrene har fastet i 12 timer inden indgivelse af dexmedetomidin.
English: Premedication with dexmedetomidine will significantly reduce the dosage of the induction agent required and will reduce volatile anaesthetic requirements for maintenance anaesthesia.
Danish: Præmedicinering med dexmedetomidin vil nedsætte den påkrævede dosis af induktionsmidlet signifikant samt reducere mængden af anæstesigasser der krævestil vedligeholdelse af anæstesien.
English: Intravenously: up to 375 micrograms/square metre body surface area Intramuscularly: up to 500 micrograms/square metre body surface area
Danish: Den intravenøse dosis er: op til 375 mikrogram pr. kvadratmeter legemsoverflade Den intramuskulære dosis er: op til 500 mikrogram pr. kvadratmeter legemsoverflade
English: - Dogs: intravenous or intramuscular use - Cats: intramuscular use
Danish: Hunde: intravenøs eller intramuskulær anvendelse Katte: intramuskulær anvendelse