FrancophonIA/ELRC3.0 huggingface dataset:
English: In addition, the following applies to use of the infusion bottle containing 65 ml: The contrast medium must be administered by means of an automatic injector.
Slovenian: Poleg tega velja za uporabo infuzijske steklenice, ki vsebuje 65 ml, naslednje: Kontrastno sredstvo je treba dati z avtomatskim injektorjem.
English: EXP {MM/YYYY} [7.5 ml / 15 ml / 30 ml:]
Slovenian: [7,5 ml/15 ml/30 ml:]
English: Mommaertslaan, 14 1831 Machelen (Diegem) Belgium
Slovenian: Mommaertslaan, 14 1831 Machelen (Diegem) Belgija
English: Average specificity in a patient-based analysis was 52% and in a lesion-based analysis 82%.
Slovenian: Povprečna specifičnost je bila pri analizi na temelju števila bolnikov 52 %, pri analizi na temelju števila lezij pa 82 %.
English: Due to potential effects of Gadovist on cardiac repolarization in cases of overdose, disturbances of cardiac rhythm may be possible.
Slovenian: Ker Gadovist lahko vpliva na repolarizacijo srca, so v primeru prevelikega odmerjanja možne motnje srčnega ritma.
English: If a strong clinical suspicion of a lesion persists despite an unremarkable MRI or when more accurate information might influence therapy of the patient, a further injection of up to 0.2 mmol/kg BW within 30 minutes of the first injection may be performed.
Slovenian: Če kljub neznačilni sliki MRS obstaja močan klinični sum na lezijo ali kadar bi natančnejše informacije lahko vplivale na zdravljenje, se lahko v 30 minutah po prvi injekciji injicira dodatnih 0,2 mmol/kg TM.
English: It should be visually inspected before use.
Slovenian: Pred uporabo ga je treba vizualno pregledati.
English: Within the range 0.47 to 2.0 Tesla, the relaxivity displays only slight dependency on the strength of the magnetic field.
Slovenian: V vrednosti od 0,47 do 2,0 Tesle je relaksativnost le rahlo odvisna od jakosti magnetnega polja.
English: the Committee considered the referral made under Article 36(1) of Directive 2001/83/EC, as amended for Gadovist detailed in Annex I;
Slovenian: Ob upoštevanju, da je Odbor upošteval napotitveni postopek v skladu s členom 36(1) Direktive 2001/83/ES, kot je bila spremenjena, za zdravilo Gadograf in z njim povezana imena, ki so navedena v Dodatku I;
English: In clinical doses, gadobutrol leads to shortening of the relaxation times of protons in tissue water.
Slovenian: V kliničnih odmerkih gadobutrol skrajša relaksacijske čase protonov vode v tkivu.
English: Referral Procedure
Slovenian: Napotitveni postopek
English: MRI is a form of medical diagnostic imaging that uses the behaviour of water molecules in normal and abnormal tissues.
Slovenian: MRS je oblika diagnostičnega slikanja v medicini, pri katerem se opazuje vedenje molekul vode v normalnih in nenormalnih tkivih.
English: Further information regarding the administration and handling of Gadovist is given at the end of the leaflet.
Slovenian: Dodatne informacije o uporabi zdravila Gadovist in ravnanju z njim so na koncu teh navodil.
English: DATE OF REVISION OF THE TEXT {MM/YYYY} [To be completed nationally]
Slovenian: DATUM ZADNJE REVIZIJE BESEDILA {MM/LLLL} [Izpolni država članica]
English: D - 13342 Berlin, Germany Telephone: +49 30 468-1111
Slovenian: D 13342 Berlin, Nemčija Telefon: +49 30 468-1111
English: This medicinal product should be visually inspected before use.
Slovenian: To zdravilo je treba pred uporabo vizualno pregledati.
English: Gadovist should not be used during pregnancy unless clearly necessary.
Slovenian: Zdravila Gadovist ne smete uporabljati med nosečnostjo, razen če je nujno.
English: Less than 0.1% of the dose is eliminated via the faeces.
Slovenian: Manj kot 0,1 % odmerka se izloči z blatom.
English: If you have any further questions, please ask your doctor or the person giving you Gadovist (the radiologist) or the hospital/MRI-centre personnel.
Slovenian: Če imate dodatna vprašanja, se posvetujte z zdravnikom ali z osebo, ki vam daje zdravilo Gadovist (radiologom), ali z bolnišničnim osebjem/osebjem oddelka za magnetnoresonančno slikanje.
English: Side effects which have been observed in clinical trials before the approval of Gadovist: Uncommon
Slovenian: Neželeni učinki, ki so jih opazili v kliničnih preskušanjih pred odobritvijo uporabe zdravila Gadovist: Občasni
English: Hypersensitivity reactions, as have been reported for other contrast media containing gadolinium, have also been observed after administration of Gadovist.
Slovenian: Preobčutljivostne reakcije, o katerih so poročali pri uporabi drugih kontrastnih sredstev, ki vsebujejo gadolinij, so opazili tudi po uporabi zdravila Gadovist.
English: Breast feeding should be discontinued for at least 24 hours after the administration of gadobutrol.
Slovenian: Dojenje je treba prekiniti vsaj 24 ur po uporabi gadobutrola.
English: Gadovist was the first paramagnetic contrast agent developed in a 1.0 molar solution thus requiring a smaller application volume in a higher dosage.
Slovenian: Gadograf je prvo paramagnetno kontrastno sredstvo s koncentracijo 1,0 mol, kar omogoča manjši aplikacijski volumen pri višjih odmerkih.
English: The MAH further agreed to the proposed wording by the CHMP as follows:
Slovenian: V odgovoru se je imetnik dovoljenja za promet z zdravilom strinjal z besedilom, ki ga predlaga CHMP, in sicer:
English: IRE - Ireland
Slovenian: IRE - Irska
English: The MAH was requested to reply to the following Questions:
Slovenian: Odbor je zaprosil imetnika dovoljenja za promet z zdravilom, da odgovori na naslednja vprašanja:
English: - Handling
Slovenian: - Ravnanje
English: Optimal opacification is observed during arterial first pass for CE-MRA and within a period of about 15 minutes after injection of Gadovist for CNS indications (time depending on type of lesion/tissue).
Slovenian: Opacifikacija za slikanje CE-MRA je optimalna med prvim arterijskim prehodom, za indikacije pri slikanju CŽS pa v obdobju približno 15 minut po injiciranju zdravila Gadovist (čas je odvisen od vrste lezije/tkiva).
English: Like all medicines, Gadovist can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo Gadovist neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Gadovist should be used with special care in patients - with known congenital long QT syndrome or a family history of congenital long QT syndrome - with known previous arrhythmias after taking medicinal products that prolong cardiac repolarisation - who are currently taking a medicinal product that is known to prolong cardiac repolarisation e.g. a Class III antiarrhythmic (e.g. amiodarone, sotalol).
Slovenian: Zdravilo Gadovist je treba uporabljati posebno previdno pri bolnikih: - z znanim sindromom prirojenega dolgega intervala QT ali družinsko anamnezo sindroma prirojenega dolgega intervala QT; - z aritmijami, ki so se v preteklosti pojavile po jemanju zdravil, ki podaljšajo repolarizacijo srca; - ki trenutno jemljejo zdravila, za katera je znano, da podaljšujejo repolarizacijo srca, npr. antiaritmike III skupine (npr. amiodaron, sotalol).
English: Having considered the response provided by the MAH and assessed by the Rapporteurs, on 16 November 2006, the CHMP adopted a Request of Supplementary Information, in which the MAH was asked to further expand on the issue of clinical utility and to comment on a proposed wordings regarding the Indication in 4.1 and the Posology in 4.2 of the SPC.
Slovenian: CHMP je 16. novembra 2006 po preučitvi odgovorov, ki jih je predložil imetnik dovoljenja za promet z zdravilom in ki so jih nato preučili poročevalci, sprejel Zahtevek za dodatne informacije, v katerem imetnika dovoljenja za promet z zdravilom naproša, da dodatno obrazloži klinično uporabnost in komentira predlagano besedilo indikacije v poglavju 4.1 in odmerjanja v poglavju 4.2 Povzetka glavnih značilnosti zdravila (SPC).
English: Moreover, the wording of the indication should also reflect the clinical context for which Gadovist has demonstrated to have the same diagnostic accuracy than its comparator, that is to correctly localise at least one malignant lesion of liver or kidney in an individual patient using combined pre- and post-contrast MR images.
Slovenian: Poleg tega mora besedilo indikacije odražati tudi klinični kontekst, v katerem je bila za Gadograf dokazana enaka diagnostična natančnost kot za primerjalno zdravilo, kar pomeni pravilno lokalizacijo najmanj ene maligne lezije v jetrih ali ledvicah pri posameznem bolniku na osnovi kombiniranja kontrastiranih MRI slik pred in potem.
English: Further information regarding the use of Gadovist is given in section 3 of the leaflet.
Slovenian: Dodatne informacije o uporabi zdravila Gadovist so v poglavju 3 tega navodila za uporabo.
English: Additional side effects which have been reported after the approval of Gadovist:
Slovenian: Drugi neželeni učinki, o katerih so poročali po odobritvi uporabe zdravila Gadovist:
English: As only those patients with high suspicion or evidence of having a focal disease of liver or kidneys obtained by other diagnostic tests or histopathology were included in the two pivotal studies, the indication approved must reflect the studied population and not in general for any patient undergoing a contrast enhanced MRI of liver or kidneys.
Slovenian: Ker so bili v obe ključni raziskavi vključeni le bolniki, pri katerih je obstajal močan sum ali dokaz za fokalno bolezen jeter ali ledvic, pridobljen na osnovi drugih diagnostičnih ali histopatoloških preiskav, mora odobrena indikacija odražati preučevano populacijo in ne vseh bolnikov na splošno, pri katerih se opravlja MRI jeter ali ledvic z izboljšanim kontrastom.
English: Gadovist may cause local pain lasting up to several minutes if it is injected beside the vein.
Slovenian: Zdravilo Gadovist povzroči več minut trajajočo lokalno bolečino, če se injicira poleg vene.
English: MRI is a widely used technique for the evaluation and detection of diffuse liver disease as well as for further characterization of focal liver disease.
Slovenian: MRI je razširjena tehnika za preiskovanje in odkrivanje difuznih bolezni jeter ter za podrobno opredelitev fokalnih jetrnih bolezni.
English: The MAH has updated SPC sections 4.1 and 4.2 in accordance with the requests of the CHMP.
Slovenian: Imetnik dovoljenja za promet z zdravilom je popravil poglavji 4.1 in 4.2 v Povzetku glavnih značilnosti zdravila skladno z zahtevami CHMP.
English: D-13342 Berlin- Mitte Germany
Slovenian: D-13342 Berlin- Mitte Nemčija
English: The recommended dose for adults is 0.1 mmol per kilogram body weight (mmol/kg BW).
Slovenian: Priporočeni odmerek za odrasle je 0,1 mmol na kilogram telesne mase (mmol/kg TM).
English: Therefore, the possibility that Gadovist may cause torsade de pointes arrhythmias in an individual patient can not be excluded.
Slovenian: Torej možnosti, da zdravilo Gadovist lahko pri posameznih bolnikih povzroči aritmije torsade de pointes, ni mogoče izključiti.
English: While injecting Gadovist into veins with a small lumen there is the possibility of adverse effects such as reddening and swelling.
Slovenian: Pri injiciranju zdravila Gadovist v vene z majhno svetlino obstaja možnost neželenih učinkov, kot sta pordelost in otekanje.
English: Do not use GADOVIST - if you are allergic (hypersensitive) to gadobutrol or any of the other ingredients of
Slovenian: Ne uporabljajte zdravila GADOVIST - če ste alergični na (preobčutljivi za) gadobutrol ali katerokoli sestavino zdravila Gadovist (glejte "Kaj vsebuje zdravilo Gadovist").
English: Below we list possible side effects by how likely they are, using the following categories: Uncommon: between 1 and 10 in every 1000 patients are likely to get these.
Slovenian: Spodaj so po svoji verjetnosti navedeni možni neželeni učinki, razvrščeni v naslednji skupini: Občasni: verjetno se bodo pojavili pri manj kot 1 bolniku od 100 in več kot 1 bolniku od 1.000.
English: Like with other gadolinium containing contrast agents special precaution is necessary in patients with a low threshold for seizures.
Slovenian: Kot pri vseh kontrastnih sredstvih, ki vsebujejo gadolinij, je treba biti posebno previden pri bolnikih z nizkim pragom za konvulzije.
English: SV - Sweden
Slovenian: SV - Švedska
English: WHAT GADOVIST IS AND WHAT IT IS USED FOR
Slovenian: Kaj je zdravilo GADOVIST in za kaj ga uporabljamo 2.
English: 2) The requested indication cannot be approved for paediatric population aged less than 18 years since there is no data on the efficacy and safety of the use of Gadovist for contrast-enhancement MRI in this population in the submitted pivotal studies.
Slovenian: Zahtevane indikacije ni možno odobriti za otroke, mlajše od 18 let, saj v okviru predloženih ključnih raziskav niso bili zbrani podatki o učinkovitosti in varnosti uporabe zdravila Gadograf pri MRI z izboljšanim kontrastom v tej populaciji.
English: Any solution not used in one examination is to be discarded in accordance with local requirements.
Slovenian: Vso raztopino, ki je ne uporabite pri enem pregledu, morate odstraniti skladno z lokalnimi predpisi.
English: Since the issue of clinical utility was satisfactorily addressed and the MAH agreed to the proposed wording, the CHMP is of the opinion that the data provided allow the conclusion that, on basis of the pivotal clinical studies comparing Gadovist-enhanced with Magnevist-enhanced MRI, diagnostic efficacy of Gadovist for the classification of focal liver or renal lesions as benign or malignant, as well as clinical safety of Gadovist has been adequately established.
Slovenian: Ker je bilo vprašanje klinične uporabnost zadovoljivo obravnavano in se imetnik dovoljenja za promet z zdravilom strinja s predlaganim besedilom, CHMP meni, da lahko na osnovi predloženih podatkov zaključi, da je ob upoštevanju ključnih kliničnih raziskav primerjave MRI, katerega kontrast je izboljšan z zdravilom Gadograf, in MRI, katerega kontrast je izboljšan z zdravilom Magnevist, zadostno dokazana diagnostična učinkovitost zdravila Gadograf za opredelitev benignosti ali malignosti fokalnih jetrnih ali ledvičnih lezij ter klinična varnost tega zdravila.
English: The dose required is administered intravenously as a bolus injection.
Slovenian: Potrebni odmerek se daje intravensko v obliki bolusne injekcije.
English: Hypersensitivity reactions (e.g. urticaria, rash, vasodilitation) have been uncommonly reported and were mostly of mild to moderate intensity.
Slovenian: O preobčutljivostnih reakcijah (npr. urtikarija, izpuščaj, vazodilatacija) so poročali občasno, te reakcije pa so bile večinoma blage do zmerne.
English: No signs of intoxication from an overdose have so far been observed during clinical use.
Slovenian: Pri klinični uporabi doslej niso opažali znakov intoksikacije zaradi prevelikega odmerjanja.
English: The maximum daily single dose tested in humans is 1.5 mmol gadobutrol/kg body weight.
Slovenian: Največji enkratni dnevni odmerek preiskovan pri ljudeh je 1,5 mmol gadobutrola/kg telesne mase.
English: After first opening use immediately within 24 h (stored 2 - 8 °C).
Slovenian: Porabite v 24 urah po prvem odprtju (shranjeno pri temperaturi 2-8 °C).
English: A single injection of 0.1 millilitre Gadovist per kg body weight is generally sufficient (this means for a person weighing 70 kg the dose would be 7 millilitres).
Slovenian: Na splošno zadostuje enkratno injiciranje 0,1 mililitra zdravila Gadovist na kg telesne mase (to pomeni, da bi bil za osebo, ki tehta 70 kg, odmerek 7 mililitrov).
English: Paramagnetic contrast media
Slovenian: Paramagnetno kontrastno sredstvo.
English: In June 2005 a MR procedure started with Germany as the RMS for a Type II variation to add the indication of “Contrast enhanced MRI of other body regions: liver, kidneys” and the following posology and method of administration/dosage: “CE-MRI of other body regions: The recommended dose for adults is 0.1 mmol per kilogram body weight (mmol/kg BW).
Slovenian: Postopek se je nanašal na variacijo tipa II za dodatek indikacije „MRI z izboljšanim kontrastom za druge dele telesa: jetra, ledvice“ in naslednje navedbe odmerjanja in načina uporabe/odmerjanja: „CE-MRI za druge dele telesa: Priporočeni odmerek za odrasle je 0,1 mmol na kilogram telesne mase (mmol/kg TM).
English: In rare cases delayed anaphylactoid reactions (after hours to days) have been observed.
Slovenian: V redkih primerih so opazili pozne anafilaktoidne reakcije (po več urah ali dneh).
English: Up to 0.4 mmol gadobutrol/kg body weight, the plasma level declines after an early distribution phase with a mean terminal half-life of 1.8 hours (1.3 - 2.1 hours), identical to the renal elimination rate.
Slovenian: Do odmerka 0,4 mmol gadobutrola/kg telesne mase je koncentracija v plazmi po zgodnji porazdelitveni fazi upadala s srednjim končnim razpolovnim časom 1,8 ur (1,3-2,1 ure), identično hitrosti ledvičnega izločanja.
English: DA - Denmark
Slovenian: DA - Danska
English: Chemical and physical inuse stability has been demonstrated for 24 hours at room temperature.
Slovenian: Dokazano je bilo, da je raztopina pri sobni temperaturi stabilna 24 ur.
English: After intravenous administration, gadobutrol is rapidly distributed in the extra cellular space.
Slovenian: Po intravenski uporabi se gadobutrol hitro razporedi v zunajcelični prostor.
English: Schering Deutchland GmbH
Slovenian: DE - Nemčija Schering Deutchland GmbH Gadovist
English: Special precautions for storage of sterile product which has been opened are described in section 6.3.
Slovenian: Posebna navodila za shranjevanje sterilnega zdravila, ki je bilo odprto, so opisana v poglavju 6.3. 6.5 Vrsta ovojnine in vsebina
English: BATCH NUMBER Lot {number}
Slovenian: ŠTEVILKA SERIJE Serija {številka}
English: Patients with an allergic disposition suffer more frequently than others from hypersensitivity reactions.
Slovenian: Preobčutljivostne reakcije so pogostejše pri bolnikih, nagnjenih alergijam, kot pri drugih.
English: A label extension to the indication “Contrast-enhanced Magnetic resonance angiography” (CE-MRA) followed in November 2003.
Slovenian: Novembra 2003 je sledila razširitev indikacije na „magnetno resonančno angiografijo z izboljšanim kontrastom“ (CE-MRI).
English: The contrast-enhancing effect is mediated by gadobutrol, the nonionic complex consisting of gadolinium(III) and the macrocyclic ligand dihydroxy-hydroxymethylpropyl-tetraazacyclododecanetriacetic acid (butrol).
Slovenian: Povečanje kontrasta povzroči gadobutrol, neionski kompleks, sestavljen iz gadolinija (III) in makrocikličnega liganda dihidroksi-hidroksimetilpropil-tetraazaciklododekan-triocetne kisline (butrola).
English: 1 and 5 prefilled syringes
Slovenian: 1 in 5 napolnjenih injekcijskih brizg
English: Gadovist should only be administered by physicians experienced in the field of clinical MRI practice.
Slovenian: Zdravilo Gadovist sme dajati samo zdravnik z izkušnjami na področju klinične uporabe MRI.
English: Shelf life of the medicinal product as packaged for sale: 3 years
Slovenian: Rok uporabnosti zdravila, pakiranega za prodajo:
English: Invented name Strength
Slovenian: Izmišljeno ime zdravila
English: Take special care with GADOVIST - if you suffer or have suffered from allergy (e.g. hay fever, hives) or asthma - if you had a previous reaction to contrast media - if you have a very poor kidney function - if you have a serious disease of the heart and blood vessels - if you suffer from low potassium levels - if you, or someone in your family, has ever had problems with the electrical rhythm of the heart
Slovenian: Bodite posebno pozorni pri uporabi zdravila GADOVIST - če imate ali ste imeli alergijo (na primer seneni nahod ali koprivnico) ali astmo; - če ste v preteklosti imeli reakcije na kontrastna sredstva; - če imate oslabele ledvice; - če imate resno bolezen srca ali krvnih žil; - če imate nizko raven kalija; - če ste vi ali kdo v vaši družini imeli težave z električnim ritmom srca (sindrom dolgega intervala QT); - če ste kadar koli po jemanju zdravil imeli spremembe srčnega ritma ali hitrosti utripa; - če imate bolezni možganov z epileptičnimi napadi, ki izvirajo iz drugih bolezni živčevja.
English: On paravascular injection Gadovist may cause tissue pain lasting up to several minutes.
Slovenian: Pri paravaskularnem injiciranju lahko zdravilo Gadovist povzroči več minut trajajočo bolečino v tkivu.
English: After first opening use immediately within 24 h (stored 2 - 8 °C) or within 8 h (stored at r.t.)
Slovenian: Porabite v 24 urah po prvem odprtju (shranjeno pri temperaturi 2-8 °C) ali v 8 urah (shranjeno pri sobni temperaturi.)
English: Adverse reactions are “rare (≥1/10,000 to <1/1,000)” to “uncommon (≥1/1,000 to <1/100)”.
Slovenian: Neželeni učinki so "redki (≥ 1/10.000 do < 1/1.000)" do "občasni (≥ 1/1.000 do < 1/100)".
English: Intravascular administration of contrast media should, if possible, be done with the patient lying down.
Slovenian: Kontrastno sredstvo je treba uporabiti intravaskularno tako, da bolnik leži, če je mogoče.
English: Repeated dosing in reproduction toxicological studies caused a retardation of embryonal development in rats and an increase in embryolethality in monkeys and in rabbits at maternally toxic dose levels (8 to 17 times the diagnostic dose) only.
Slovenian: V študijah reproduktivne toksičnosti je ponavljajoče odmerjanje povzročilo zaostajanje embrionalnega razvoja pri podganah in povečanje embrioletalnosti pri opicah in kuncih le pri maternalno toksičnih odmerkih (8- do 17-kratni diagnostični odmerek).
English: Gadovist is not recommended for use in population below age 18 due to a lack of data on efficacy and safety.
Slovenian: Uporaba zdravila Gadovist se ne priporoča za uporabo pri populaciji mlajši od 18 let zaradi pomanjkanja podatkov o varnosti in učinkovitosti.
English: Further to the approval Spain raised a major objection related to the wording of the indication as Spain considered that the approved indication neither reflected the studied population in the two pivotal studies submitted for this variation of Gadovist nor the clinical context for which Gadovist has demonstrated to have the same diagnostic accuracy than its comparator.
Slovenian: Kljub odobritvi je Španija predložila pomemben ugovor glede besedila indikacije, saj Španija meni, da odobrena indikacija ne odraža niti preučevane populacije v dveh ključnih raziskavah, ki sta bili predloženi za variacijo dovoljenja za Gadograf, niti kliničnega konteksta, v katerem je bila za Gadograf dokazana enaka diagnostična natančnost kot za primerjalno zdravilo.
English: The CHMP has recommended the variation (extension of indication) of the Marketing Authorisation in accordance with the Summary of Product Characteristics set out in Annex III for Gadovist (see Annex I).
Slovenian: CHMP je za Gadograf in z njim povezana imena (glejte Dodatek I) priporočil variacijo (razširitev indikacije) dovoljenja za promet z zdravilom v skladu s Povzetkom glavnih značilnosti zdravila, opredeljenim v Dodatku III.
English: HOW TO USE GADOVIST
Slovenian: KAKO UPORABLJATI ZDRAVILO GADOVIST
English: Max-Dohm-Strasse 8-10 D-10589 Berlin
Slovenian: Max-Dohrn-Strasse 10 D-10589 Berlin injekcijski brizgi
English: In the response the MAH acknowledges with reference to Question 1) that the patient population studied in the pivotal trials has some limitations in comparison to the overall anticipated patient population undergoing CE-MRI, but these limitations are the result of methodological requirements to adequately demonstrate the diagnostic efficacy of Gadovist-enhanced MRI in the pivotal studies.
Slovenian: V odgovoru se imetnik dovoljenja za promet z zdravilom glede prvega vprašanja strinja, da ima populacija, ki je bila preučena v ključnih raziskavah, nekaj omejitev v primerjavi s splošno populacijo, za katero se pričakuje uporaba CE-MRI, vendar te omejitve izvirajo iz metodoloških zahtev za zadosten dokaz diagnostične učinkovitosti uporabe zdravila Gadograf pri MRI.
English: Gd-based contrast agents are frequently administered prior to contrast-enhanced dynamic liver MRI and may improve both detection and classification of focal liver lesions.
Slovenian: Kontrastna sredstva na osnovi Gd se pogosto dajejo pred dinamičnim MRI za jetra z izboljšanim kontrastom, saj lahko izboljšajo odkrivanje in razvrstitev fokalnih jetrnih lezij.
English: Large volume containers
Slovenian: Vsebniki z veliko prostornino