FrancophonIA/ELRC3.0 huggingface dataset:
English: If deemed necessary, a second dose of 400 micrograms can be injected at least 10 minutes after the first dose for such pressure difference measurement during the same catheterization procedure.
Croatian: Ako se smatra potrebnim, za ovakvo mjerenje razlike u tlaku se tijekom istog postupka kateterizacije može ubrizgati druga doza od 400 mikrograma, ali tek nakon što je prošlo najmanje 10 minuta od prve doze.
English: In post-marketing experience there have also been reports of cerebrovascular accident (CVA).
Croatian: Nakon stavljanja lijeka u promet zabilježeni su i slučajevi cerebrovaskularnog inzulta.
English: Treatment with Rapiscan is restricted to use in a medical facility where cardiac monitoring and resuscitation equipment are available.
Croatian: Primjena Rapiscana je ograničena na primjenu u medicinskim ustanovama u kojima postoji mogućnost nadziranja rada srca i dostupna je oprema za reanimaciju.
English: Fertility Fertility studies with regadenoson have not been performed (see section 5.3).
Croatian: Plodnost Ispitivanja utjecaja regadenosona na plodnost nisu provedena (vidjeti dio 5.3).
English: Regadenoson should be used with caution and should only be administered in a medical facility with cardiac monitoring and resuscitation equipment.
Croatian: Regadenoson se treba koristiti s oprezom i smije ga se primjenjivati samo u zdravstvenim ustanovama u kojima postoji mogućnost nadziranja rada srca i dostupna je oprema za reanimaciju.
English: • if you have slow heart rate (high degree heart block or sinus node disease), and don't have a pacemaker fitted.
Croatian: Nemojte uzimati Rapiscan - ako imate spore otkucaje srca (visoki stupanj srčanog bloka ili bolestan sinusni čvor), a nemate ugrađen električni stimulator srca (pacemaker).
English: • radionuclide myocardial perfusion imaging (MPI) in patients unable to undergo adequate exercise stress.
Croatian: • slikovnoj dijagnostici perfuzije miokarda pomoću radionuklida u bolesnika koje nije moguće podvrći odgovarajućem testu opterećenja tjelesnim naporom
English: Patients with a recent history of serious uncontrolled ventricular arrhythmia, myocardial infarction, or unstable angina, a history of greater than first degree AV block, or with symptomatic bradycardia, sick sinus syndrome, or a heart transplant were excluded.
Croatian: Bolesnici koji su u anamnezi nedavno imali nekontroliranu ventrikularnu aritmiju, infarkt miokarda ili nestabilnu anginu pektoris, AV blok drugog i trećeg stupnja ili simptomatsku bradikardiju, sindrom bolesnog sinusnog čvora (sick sinus syndrome) ili transplantaciju srca, isključeni su iz ispitivanja.
English: The other ingredients are: disodium edetate, disodium phosphate dihydrate, sodium dihydrogen phosphate monohydrate, propylene glycol, water for injections.
Croatian: Drugi sastojci su: dinatrijev edetat, natrijev hidrogenfosfat dihidrat, natrijev dihidrogenfosfat hidrat, propilenglikol, voda za injekcije.
English: If deemed necessary, a second dose of 400 micrograms can be injected at least 10 minutes after the first dose for FFR measurement during the same catheterization procedure.
Croatian: Ako se smatra potrebnim, za mjerenje FFR-a se tijekom istog postupka kateterizacije može ubrizgati druga doza od 400 mikrograma, ali tek nakon što je prošlo najmanje 10 minuta od prve doze.
English: Dipyridamole
Croatian: Dipiridamol
English: Patients should remain sitting or lying down and be monitored at frequent intervals after the injection until the ECG parameters, heart rate and blood pressure have returned to pre-dose levels.
Croatian: Nakon injekcije bolesnici trebaju ostati u sjedećem ili ležećem položaju te ih treba nadzirati sve dok se EKG-parametri, srčana frekvencija i krvni tlak ne vrate na vrijednosti prije primljene doze.
English: General disorders and administration site conditions: Very common Chest pain Common
Croatian: Opći poremećaji i reakcije na mjestu primjene: Vrlo često bol u prsnom košu
English: To be taken into consideration if you are on a controlled sodium diet.
Croatian: Ovo treba uzeti u obzir ako ste na prehrani s ograničenjem unosa natrija.
English: However, most adverse reactions are mild and transient, resolving within 30 minutes after receiving regadenoson.
Croatian: Nuspojave su većinom blage i prolazne, i povlače se unutar 30 minuta od primjene regadenosona.
English: Heart rate and blood pressure will be monitored during the entire procedure.
Croatian: Za vrijeme trajanja cijelog postupka nadzire se puls i tlak.
English: The efficacy and safety of regadenoson for pharmacologic stress radionuclide MPI were determined relative to adenosine in two randomised, double- blind studies (ADVANCE MPI 1 and ADVANCE MPI 2) in 2,015 patients with known or suspected coronary artery disease who were referred for a clinically-indicated pharmacologic stress MPI.
Croatian: Primjena farmakološkog stresa za slikovnu dijagnostiku perfuzije miokarda (MPI) pomoću radionuklida Djelotvornost i sigurnost regadenosona kao farmakološkog stresnog agensa za slikovnu dijagnostiku perfuzije miokarda pomoću radionuklida određena je u odnosu na adenozin u dva randomizirana dvostruko slijepa ispitivanja (ADVANCE MPI 1 i ADVANCE MPI 2) na 2015 bolesnika s postojećom ili sumnjom na postojanje koronarne bolesti koji su upućeni radi klinički indiciranog farmakološkog stresa radi MPI.
English: In the first study in 49 patients with moderate to severe COPD, the rate of FEV1 reduction > 15% from baseline was 12% and 6% following regadenoson and placebo dosing, respectively (p=0.31).
Croatian: U prvom ispitivanju na 49 bolesnika s umjerenom do teškom KOPB stopa smanjenja FEV1 > 15% od početnih vrijednosti bila je 12% odnosno 6% nakon primjene doze regadenosona odnosno placeba (p = 0,31).
English: Fatal cardiac arrest, life-threatening ventricular arrhythmias, and myocardial infarction may result from the ischaemia induced by pharmacologic stress agents like regadenoson.
Croatian: Fatalni kardijalni zastoj, po život opasne ventrikularne aritmije i infarkt miokarda mogu biti posljedica ishemije inducirane farmakološkim stresnim agensima poput regadenosona.
English: The metabolism of regadenoson is unknown in humans.
Croatian: Nije poznat način metaboliziranja regadenosona u ljudi.
English: Cardiac arrest, myocardial infarction, complete AV block, bradycardia, atrial flutter, new-onset, worsening or recurrence of atrial fibrillation
Croatian: Manje često srčani zastoj, infarkt miokarda, potpuni AV blok, bradikardija, undulacija atrija, pojava nove, pogoršanje ili ponovna pojava fibrilacije atrija Krvožilni poremećaji: Vrlo često naleti crvenila
English: Uncommon side effects (affects 1 to 10 users in 1,000)
Croatian: Manje česte nuspojave (pojavljuju se kod 1 do 10 bolesnika na 1000)
English: For diagnostic use only.
Croatian: Samo u dijagnostičke svrhe.
English: There are no adequate data from the use of regadenoson in pregnant women.
Croatian: Nema dovoljno podataka o primjeni regadenosona u trudnica.
English: • an allergic reaction which can cause rash, wheals/weals, swelling under the skin near the eyes or throat, throat tightness, difficulty breathing
Croatian: • alergijska reakcija koja može uzrokovati osip, urtikariju, oticanje potkožnog tkiva oko očiju ili grla,
English: Rapiscan 400 microgram solution for injection
Croatian: Rapiscan 400 mikrograma otopina za injekciju
English: Aminophylline may be used to attenuate severe and/or persistent adverse reactions to regadenoson but should not be used solely for the purpose of terminating a seizure induced by Rapiscan (see section
Croatian: Aminofilin se smije primjenjivati za ublažavanje teških i/ili dugotrajnih nuspojava regadenosona, ali se ne smije primjenjivati isključivo u svrhu zaustavljanja konvulzija izazvanih Rapiscanom (vidjeti dio 4.4).
English: Aminophylline may be used to attenuate severe or persistent adverse reactions to regadenoson but should not be used solely for the purpose of terminating a seizure induced by regadenoson (see section 4.4).
Croatian: Aminofilin se može primjenjivati za ublažavanje teških ili dugotrajnih nuspojava regadenosona, ali se ne smije koristiti isključivo u svrhu zaustavljanja konvulzija izazvanih regadenosonom (vidjeti dio 4.4).
English: Aminophylline
Croatian: Aminofilin
English: The radiopharmaceutical for the myocardial perfusion imaging agent should be administered 10-20 seconds after the sodium chloride 9 mg/ml (0.9%) solution for injection.
Croatian: Radiofarmaceutik za slikovni prikaz perfuzije miokarda treba primijeniti 10-20 sekundi nakon 0,9%-tne otopine natrijeva klorida za injekciju (9 mg/ml).
English: Elderly No dose adjustment is necessary (see section 5.2).
Croatian: Starije osobe Prilagođavanje doze nije potrebno (vidjeti dio 5.2).
English: UNIQUE IDENTIFIER - 2D BARCODE
Croatian: Prihvaćeno obrazloženje za nenavođenje Brailleovog pisma 17. JEDINSTVENI IDENTIFIKATOR - 2D BARKOD
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Croatian: • Periodička izvješća o neškodljivosti lijeka (PSUR-evi) Zahtjevi za podnošenje PSUR-eva za ovaj lijek definirani su u referentnom popisu datuma EU (EURD popis) predviđenom člankom 107.c stavkom 7.
English: Throat tightness, throat irritation, cough
Croatian: • stezanje u grlu, nadražaj u grlu, kašalj
English: • pain in the joints
Croatian: • bol u zglobovima
English: Regadenoson is administered by intravenous injection for pharmacologic stress radionuclide MPI.
Croatian: Regadenoson se primjenjuje u obliku intravenske injekcije kao farmakološki stresni agens za slikovnu dijagnostiku perfuzije miokarda pomoću radionuklida.
English: Excipients: Disodium phosphate dihydrate, sodium dihydrogen phosphate monohydrate, propylene glycol, disodium edetate, water for injections
Croatian: Pomoćne tvari: natrijev hidrogenfosfat dihidrat, natrijev dihidrogenfosfat hidrat, propilenglikol, dinatrijev edetat, voda za injekcije
English: For further information, please refer to the complete Summary of Product Characteristics.
Croatian: Dodatne informacije potražite u priloženom sažetku opisa svojstava lijeka.
English: Cerebrovascular accident
Croatian: Rijetko cerebrovaskularni inzult
English: • The radiopharmaceutical for the myocardial perfusion imaging agent should be administered 10-20 seconds after the sodium chloride 9 mg/ml (0.9%) solution for injection.
Croatian: • Radiofarmaceutik za slikovni prikaz perfuzije miokarda treba primijeniti 10-20 sekundi nakon 0,9%tne otopine natrijeva klorida za injekcije (9 mg/ml).
English: ANNEX 1
Croatian: MPI 1
English: • feeling unwell or weak
Croatian: • opće loše stanje ili opća slabost
English: • theophylline, a medicine used to treat asthma and other lung diseases, must not be used for at least 12 hours before you are given Rapiscan because it can block the effect of Rapiscan.
Croatian: • teofilin, lijek koji se koristi za liječenje astme i drugih bolesti pluća, ne smije se uzeti najmanje 12
English: Hypertension, pallor, peripheral coldness Respiratory, thoracic and mediastinal disorders: Very common Dyspnoea Common
Croatian: Manje često hipertenzija, blijedilo, hladne okrajine Poremećaji dišnog sustava, prsišta i sredoprsja: Vrlo često dispneja
English: Hypersensitivity reactions including: Rash, urticaria, angioedema, anaphylaxis Psychiatric disorders:
Croatian: Poremećaji imunološkog sustava: Manje često reakcije preosjetljivosti uključujući: osip, urtikariju, angioedem, anafilaksiju
English: Following intravenous administration of
Croatian: Nakon intravenske primjene
English: However, the injection of sodium chloride 9 mg/ml (0.9%) solution given after regadenoson contains 45 mg of sodium.
Croatian: Injekcija 0,9%-tne otopine natrijeva klorida (9 mg/ml) dana nakon regadenosona sadrži 45 mg natrija.
English: Administration of aminophylline, solely for the purpose of terminating a regadenoson-induced seizure is not recommended (see section 4.4).
Croatian: Ne preporučuje se primjena aminofilina isključivo u svrhu zaustavljanja konvulzija izazvanih regadenosonom (vidjeti dio 4.4).
English: Aminophylline has been used to attenuate adverse reactions to regadenoson (see section 4.4).
Croatian: Aminofilin se primjenjivao za ublažavanje nuspojava regadenosona (vidjeti dio 4.4).
English: Pain at injection site, general body pain
Croatian: Manje često bol na mjestu injiciranja, bol u cijelom tijelu
English: Clinical studies have demonstrated the efficacy and safety of regadenoson in patients indicated for pharmacologic stress radionuclide MPI and for the measurement of FFR.
Croatian: Klinička ispitivanja dokazala su kliničku djelotvornost i sigurnost regadenosona u bolesnika kod kojih je indiciran farmakološki stres radi primjene slikovne metode prikaza perfuzije miokarda (engl.
English: In patients undergoing coronary catheterisation, pulsed-wave Doppler ultrasonography was used to measure the average peak velocity (APV) of CBF before and up to 30 minutes after administration of regadenoson (400 micrograms, intravenously).
Croatian: Coronary Blood Flow - CBF) prije primjene regadenosona i do 30 minuta nakon njegove primjene (400 mikrograma, intravenski).
English: • if you have heart failure.
Croatian: - ako bolujete od zatajenja srca.
English: This indicates that renal tubular secretion plays a role in regadenoson elimination.
Croatian: Ovo ukazuje da izlučivanje preko bubrežnih tubula ima ulogu u eliminaciji regadenosona.
English: Rapiscan 400 microgram solution for injection regadenoson
Croatian: Rapiscan 400 mikrograma otopina za injekciju regadenoson
English: No serious cardiac adverse reactions occurred in patients receiving regadenoson 1 hour following inadequate exercise stress.
Croatian: U bolesnika koji su primili regadenoson 1 sat nakon testa suboptimalnog opterećenja tjelesnim naporom nisu se pojavile ozbiljne srčane nuspojave.
English: Renal impairment No dose adjustment is necessary (see section 5.2).
Croatian: Prilagođavanje doze nije potrebno (vidjeti dio 5.2).
English: • rapid breathing
Croatian: • ubrzano disanje
English: Hepatic impairment No dose adjustment is necessary (see section 5.2).
Croatian: Oštećenje funkcije bubrega Prilagođavanje doze nije potrebno (vidjeti dio 5.2).
English: Rate Difference (regadenoson - Adenosine) (± 95% Confidence Interval
Croatian: adenozin - adenozin stopa podudarnosti (± SE) broj bolesnika (n) adenozin - regadenoson stopa podudarnosti (± SE) broj bolesnika (n) stopa različitosti (regadenoson - adenozin) (± SE) 95% CI
English: How Rapiscan is given
Croatian: Kako se primjenjuje Rapiscan
English: • FFR should be measured as the lowest value of Pd/Pa achieved during steady state hyperemia.
Croatian: • FFR treba mjeriti kao najnižu vrijednost
English: For the measurement of FFR, Rapiscan should be administered as a rapid, 10-second injection into a peripheral vein using a 22-gauge or larger catheter or needle.
Croatian: Za mjerenje FFR-a Rapiscan treba primijeniti kao brzu injekciju u perifernu venu, kroz 10 sekundi, koristeći kanilu ili iglu od 22G, ili veću.
English: • bloating, diarrhoea, involuntary loss of faeces
Croatian: • nadutost, proljev, nemogućnost zadržavanja stolice
English: If you get any side effects, talk to your doctor, or pharmacist.
Croatian: - Ako primijetite bilo koju nuspojavu, potrebno je obavijestiti liječnika ili ljekarnika.
English: See leaflet for further information.
Croatian: Dodatne informacije pogledati u uputi o lijeku.
English: Nervous system disorders:
Croatian: Psihijatrijski poremećaji:
English: Appropriate bronchodilator therapy and resuscitative measures should be available prior to regadenoson administration.
Croatian: Prije same primjene regadenosona potrebno je osigurati mogućnost primjene odgovarajuće bronhodilatacijske terapije i reanimacijskih mjera.
English: Tinnitus
Croatian: Intravenski
English: • fits, fainting, mini strokes (including weakness of the face or an inability to speak), reduced responsiveness (which may include a comatose state), trembling, sleepiness
Croatian: • napadaji, gubitak svijesti, manji moždani udari (uključujući slabost lica i nemogućnost govora),
English: Pharmacologic stress radionuclide MPI
Croatian: Slikovna dijagnostika perfuzije miokarda pomoću radionuklida (MPI) Hemodinamski učinci
English: Radionuclide myocardial perfusion imaging (MPI)
Croatian: Myocardial Perfusion Imaging - MPI) pomoću radionuklida i za mjerenje FFR.
English: Rapiscan should be administered as a rapid, 10-second injection into a peripheral vein using a 22-gauge or larger catheter or needle.
Croatian: Rapiscan treba primijeniti kao brzu injekciju u perifernu venu, kroz 10 sekundi, koristeći kanilu ili iglu od 22G ili veću.
English: Back, neck or jaw pain, pain in extremity, musculoskeletal discomfort
Croatian: Poremećaji mišićno-koštanog sustava i vezivnog tkiva: Često bol u leđima, vratu i čeljusti, bol u ekstremitetima, nelagoda u kostima i mišićima
English: • Rapiscan should be administered as a rapid, 10-second injection into a peripheral vein using a 22-gauge or larger catheter or needle.
Croatian: • Rapiscan treba primijeniti kao brzu injekciju u perifernu venu, kroz 10 sekundi, koristeći kanilu ili iglu od 22G, ili veću.
English: Vision blurred, eye pain Ear and labyrinth disorders: Uncommon
Croatian: Manje često zamagljen vid, bol u oku Poremećaji uha i labirinta:
English: Vomiting, nausea, oral discomfort
Croatian: Često povraćanje, mučnina, nelagoda u ustima
English: Usually, exercise on a treadmill is used to put the heart under stress before a scan.
Croatian: Da bi se srce podvrglo naporu prije snimanja obično se koristi traka za hodanje.
English: Abdominal distension, diarrhoea, faecal incontinence Skin and subcutaneous tissue disorders: Common
Croatian: Poremećaji kože i potkožnog tkiva: Često pojačano znojenje
English: • 5 ml of sodium chloride 9 mg/ml (0.9%) solution for injection should be administered immediately after the injection of Rapiscan.
Croatian: • Odmah nakon injekcije Rapiscana treba injicirati 5 ml 0,9%-tne otopine natrijeva klorida za injekcije (9 mg/ml).
English: Arthralgia
Croatian: Norveška
English: • chest pain
Croatian: • bol u prsnom košu
English: • 10 ml of sodium chloride 9 mg/ml (0.9%) solution for injection should be administered immediately after the injection of Rapiscan.
Croatian: • Odmah nakon injekcije Rapiscana treba injicirati 10 ml 0,9%-tne otopine natrijeva klorida za injekciju (9 mg/ml).
English: No data are available.
Croatian: Nema dostupnih podataka o primjeni u djece.
English: Fractional Flow Reserve (FFR)
Croatian: Rezerva frakcijskog protoka (FFR) Hemodinamski učinci
English: This medicinal product should be inspected visually for particulate matter and discolouration prior to administration.
Croatian: Prije primjene lijeka treba vizualno provjeriti jesu li u njemu prisutne čestice i je li promijenio boju.
English: 5 ml of sodium chloride 9 mg/ml (0.9%) solution for injection should be administered immediately after the injection of Rapiscan.
Croatian: Odmah nakon injekcije Rapiscana treba injicirati 5 ml 0,9%-tne otopine natrijeva klorida za injekciju (9 mg/ml).
English: Renal impairment
Croatian: • naleti crvenila
English: 10 mL of sodium chloride 9 mg/ml (0.9%) solution for injection should be administered immediately after the injection of Rapiscan.
Croatian: Odmah nakon injekcije Rapiscana treba injicirati 10 ml 0,9%-tne otopine natrijeva klorida za injekciju (9 mg/ml).
English: No dose adjustment is needed in patients with hepatic impairment.
Croatian: Kod bolesnika s oštećenom funkcijom bubrega nije potrebno prilagođavati dozu lijeka.
English: Hepatic impairment
Croatian: Često hipotenzija
English: Eye disorders: Uncommon
Croatian: Poremećaji oka:
English: • if you are breast-feeding.
Croatian: • ako dojite.
English: Immediate Packaging
Croatian: Farmaceutski oblik Put primjene Unutarnje pakovanje Veličina pakovanja
English: • The infusion will last about 30 minutes.
Croatian: • Infuzija će trajati približno 30 minuta.
English: Date of first authorisation: 28 June 2019
Croatian: Datum prvog odobrenja: 28. lipanj 2019.
English: These serious side effects include:
Croatian: Te ozbiljne nuspojave uključuju:
English: How much you will receive
Croatian: Koliko lijeka ćete primiti
English: • Talk to your doctor about the contraception methods that you must use during this time.
Croatian: • Razgovarajte s liječnikom o kontracepcijskim metodama koje morate koristiti tijekom tog razdoblja.
English: You may have more than one side effect at the same time.
Croatian: Možete imati i više nuspojava u isto vrijeme.
English: Unopened vial 30 months
Croatian: Neotvorena bočica 30 mjeseci
English: The events were Grade 3 or less unless stated otherwise:
Croatian: Događaji su bili 3. ili nižeg stupnja težine, osim ako nije drugačije navedeno:
English: It is very important that you do not miss a dose of this medicine.
Croatian: Vrlo je važno je da ne propustite primiti dozu ovog lijeka.
English: Call your doctor as soon as possible to make another appointment.
Croatian: Nazovite liječnika što je prije moguće kako biste dogovorili novi termin.
English: ATC code: not yet assigned
Croatian: ATK oznaka: nije još dodijeljena.
English: Additional intervention
Croatian: Dodatne intervencije
English: Your doctor will discuss these with you and will explain the risks and benefits of your treatment.
Croatian: Liječnik će s Vama o njima razgovarati i objasniti Vam rizike i koristi liječenja.
English: One of the 3 patients was treated with systemic corticosteroids.
Croatian: Jedan od 3 bolesnika bio je liječen sistemskim kortikosteroidima.
English: If you miss an appointment
Croatian: Ako propustite dogovoreni termin
English: • LIBTAYO is usually given every 3 weeks.
Croatian: • LIBTAYO se obično primjenjuje svaka 3 tjedna.
English: No overall differences in safety or effectiveness were observed between these subjects and younger subjects.
Croatian: Nisu opažene općenite razlike u sigurnosti i učinkovitosti između tih ispitanika i mlađih ispitanika.
English: • you have any other medical conditions.
Croatian: • ako imate bilo koje drugo medicinsko stanje
English: Seek urgent medical attention if you have any of the following signs or symptoms, or if they get worse:
Croatian: Odmah potražite liječničku pomoć ako primijetite bilo koji od sljedećih znakova ili simptoma ili ako se oni pogoršaju:
English: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products except those mentioned in section 6.6.
Croatian: Zbog nedostatka ispitivanja kompatibilnosti, ovaj lijek se ne smije miješati s drugim lijekovima osim onih navedenih u dijelu 6.6.
English: If you feel tired, do not drive or use machines until you feel better.
Croatian: Ako osjećate umor, nemojte upravljati vozilima niti raditi sa strojevima sve dok se ne budete osjećali bolje.
English: LIBTAYO can cause some serious side effects that you need to tell your doctor about immediately.
Croatian: LIBTAYO može uzrokovati neke ozbiljne nuspojave o kojima morate odmah obavijestiti svog liječnika.
English: • you have an autoimmune disease (a condition where the body attacks its own cells)
Croatian: • ako imate autoimunu bolest (stanje kod kojega tijelo napada vlastite stanice)
English: These animal species have similar maternal-foetal interface to that in humans.
Croatian: Kod tih je životinjskih vrsta maternofetalno sučelje slično kao u ljudi.
English: Treatment may be continued until disease progression or unacceptable toxicity.
Croatian: Liječenje se može nastaviti do progresije bolesti ili pojave neprihvatljive toksičnosti.
English: Your doctor may give you other medicines in order to stop more severe reactions and reduce your symptoms.
Croatian: Liječnik će Vam možda dati druge lijekove kako bi spriječio teže reakcije i ublažio simptome.
English: Grade 2 lasting longer than 1 week, Grade 3 or suspected
Croatian: 2. stupanj koji traje dulje od tjedan dana, 3. stupanj ili sumnja na