FrancophonIA/ELRC3.0 huggingface dataset:
English: To perform one long-term safety study where mecasermin treatment is initiated in early phase of childhood and continued to adulthood in order to investigate:
Croatian: Provesti dugoročno ispitivanje o sigurnosti primjene gdje je liječenje mekaserminom započeto u ranoj fazi djetinjstva i nastavljeno do odrasle dobi, kako bi se istražili:
English: If the patient is unable to eat, for any reason, this medicinal product should be withheld.
Croatian: Ako bolesnik ne može jesti, iz bilo kojeg razloga, ovaj lijek ne treba primijeniti.
English: Table 1 contains very common (≥ 1/10), common (≥ 1/100 to < 1/10) and uncommon (≥ 1/1000, < 1/100) adverse reactions which occurred in clinical trials.
Croatian: Tablica 1 sadrži vrlo česte (≥ 1/10), česte (≥ 1/100 do < 1/10) i manje česte (≥ 1/1000, < 1/100) nuspojave koje su se pojavljivale u kliničkim ispitivanjima.
English: • INCRELEX is contraindicated in the presence of active or suspected neoplasia, and therapy should be discontinued if evidence of neoplasia develops.
Croatian: • INCRELEX je kontraindiciran u prisustvu aktivne ili suspektne novotvorine i terapiju treba prekinuti ako se pojavi dokaz novotvorine.
English: In some cases, when deemed necessary, the physician may decide to assist in the diagnosis by performing an IGF-I generation test.
Croatian: U nekim slučajevima, kada se smatra potrebnim, liječnik može odlučiti pomoći u postavljanju dijagnoze provedbom testa stvaranja IGF-1.
English: Sleep apnea can cause excessive daytime sleepiness.
Croatian: Apneja u snu može uzrokovati prekomjernu dnevnu pospanost.
English: Reactions observed in the clinical trials
Croatian: Nuspojave primijećene u kliničkim ispitivanjima
English: Long-term overdose may result in signs and symptoms of acromegaly or gigantism.
Croatian: Dugotrajno predoziranje može rezultirati znakovima i simptomima akromegalije ili gigantizma.
English: • INCRELEX should not be administered if the patient is unable to eat for any reason.
Croatian: • INCRELEX se ne smije primjenjivati ako bolesnik ne može jesti iz bilo kojeg razloga.
English: Among all subjects included for safety evaluation (n=92), 83% of the subjects reported at least one adverse event during the course of the studies.
Croatian: Među svim ispitanicima uključenima u sigurnosnu procjenu (n=92), 83% ispitanika prijavilo je najmanje jedan štetni događaj za vrijeme trajanja ispitivanja.
English: Forty-six (57%) of the subjects were male; 66 (81%) were Caucasian.
Croatian: Četrdeset i šest (57%) ispitanika bilo je muškog spola; 66 (81%) su bili bijelci.
English: A dose adjustment may be needed for these medicines.
Croatian: Možda će biti potrebno prilagoditi dozu tih lijekova.
English: Follow the doctor's instructions for throwing away the needle and syringe.
Croatian: Postupajte po uputama liječnika za bacanje igala i štrcaljki.
English: Treatment with mecasermin is a long-term therapy.
Croatian: Liječenje mekaserminom je dugoročna terapija.
English: P-value for change from pre-Tx [1]
Croatian: P-vrijednost za promjenu u odnosu na pre-Tx [1]
English: Mecasermin may cause hypoglycaemia (very common side effect, see section 4) that may impair your ability to drive and use machines because your ability to concentrate or react may be reduced.
Croatian: Mekasermin može uzrokovati hipoglikemiju (vrlo čestu nuspojavu, pogledajte dio 4.) koja može pogoršati vašu sposobnost upravljanja vozilima i rada sa strojevima jer vaša sposobnost koncentriranja ili reagiranja može biti smanjena.
English: Hypoacusis (hearing loss)
Croatian: Hipoakuzija (gubitak sluha)
English: Before beginning treatment with INCRELEX the doctor or nurse will explain to you how to treat hypoglycaemia.
Croatian: Prije početka liječenja INCRELEXOM liječnik ili medicinska sestra će vam objasniti kako liječiti hipoglikemiju.
English: Adverse reactions not observed in clinical studies, but seen in animals at exposure levels similar to clinical exposure levels and with possible relevance to clinical use were as follows:
Croatian: Nuspojave koje nisu zabilježene u kliničkim ispitivanjima, ali su zapažene na životinjama pri razinama ekspozicije sličnim razinama ekspozicije kod ljudi i s mogućom važnošću za kliničku primjenu, bile su sljedeće:
English: Call the doctor should these symptoms bother you.
Croatian: Obratite se liječniku ako vam ti simptomi smetaju.
English: Reactions at the injection site
Croatian: Reakcije na mjestu ubrizgavanja
English: Of the 115 (28%) subjects who experienced one or more episode of hypoglycaemia, 6 subjects experienced a hypoglycaemic seizure on one or more occasion.
Croatian: Od 115 ( 28%) ispitanika koji su doživjeli jednu ili više epizoda hipoglikemije, 6 ispitanika doživjelo je hipoglikemijski napadaj jednom ili više puta.
English: The effects of mecasermin on the unborn child have not been studied.
Croatian: Učinci mekasermina na nerođeno dijete nisu ispitani.
English: These have been observed both as being systemic and/or local to the injection site.
Croatian: Ti su slučajevi primijećeni i kao sistemske i/ili kao lokalne reakcije na mjestu injiciranja.
English: Figure A: Lightly pinch the skin and inject as instructed
Croatian: Slika A: Lagano uštipnite kožu i ubrizgajte prema uputama
English: Special attention should be paid to young children, children with a history of hypoglycaemia and children with inconsistent food intake.
Croatian: Posebnu pozornost treba obratiti na malu djecu, djecu s anamnezom hipoglikemije i djecu s neredovitim unosom hrane.
English: Annual results for height velocity, height velocity SDS, and height SDS until year 8 are shown in Table 2.
Croatian: Godišnji rezultati za brzinu rasta, SDS brzine rasta i SDS visine do 8. godine prikazani su u Tablici 2.
English: LT-48100 Kaunas
Croatian: LT- 48100 Kaunas Tel.
English: Release the skin (see Figure A).
Croatian: Pustite kožu (pogledajte Sliku A).
English: No subject discontinued the studies due to adverse events.
Croatian: Niti jedan od ispitanika nije prekinuo ispitivanje radi nastalih štetnih događaja.
English: The use of this medicine has not been studied in children under 2 years of age and is therefore not recommended.
Croatian: Primjena ovog lijeka nije ispitivana kod djece mlađe od 2 godine i stoga se ne preporučuje.
English: The MAH must ensure that, at launch, all physicians who are expected to prescribe INCRELEX are provided with a “physician information pack” containing the following:
Croatian: Nositelj odobrenja mora osigurati da, u trenutku stavljanja lijeka u promet, svi liječnici od kojih se očekuje da propisuju INCRELEX budu opskrbljeni s „informacijskim paketom za liječnika” koji sadrži sljedeće:
English: Pull the needle straight out and gently press on the spot where you injected you with gauze or a cotton ball for a few seconds.
Croatian: Izvucite iglu ravno i lagano pritisnite na mjesto gdje ste si ubrizgali gazom ili pamučnom kuglicom nekoliko sekundi.
English: This reaction occurred in 71 (17%) subjects from the clinical trials and was generally associated with lack of proper rotation of injections.
Croatian: Ova reakcija pojavila se kod 71 (17%) ispitanika iz kliničkih ispitivanja i općenito je pripisana nepravilnom rotiranju mjesta injiciranja.
English: A swelling at the back of the eye (due to increased pressure within the brain) may be observed by a doctor or optician during mecasermin treatment.
Croatian: Oticanje pozadine oka (zbog povećanog tlaka unutar mozga) može se uočiti od strane liječnika ili optičara tijekom liječenja mekaserminom.
English: You should be monitored for progression of scoliosis.
Croatian: Trebate kontrole radi napredovanja skolioze.
English: • Instructions to report the onset or worsening of snoring that may indicate an increase in growth of tonsils and/or adenoids following the beginning of treatment with INCRELEX.
Croatian: • Upute za prijavu početka ili pogoršanja hrkanja što može ukazivati na povećanje rasta tonzila i/ili adenoida nakon početka liječenja INCRELEXOM.
English: You should always have a source of sugar such as orange juice, glucose gel, sweets, or milk available in case symptoms of hypoglycaemia occur.
Croatian: Uvijek trebate imati dostupan izvor šećera kao što su sok od naranče, glukozni gel, slatkiše ili mlijeko ako se jave simptomi hipoglikemije.
English: Doses of insulin and/or other hypoglycaemic medicinal products may need to be reduced (see section 4.4).
Croatian: Možda će biti potrebno smanjiti doze inzulina i/ili drugih hipoglikemijskih lijekova (vidjeti dio 4.4).
English: Pharmacotherapeutic group: Pituitary and hypothalamic hormones and analogues, somatropin and somatropin agonists, ATC code: H01AC03
Croatian: Farmakoterapijska skupina: Hormoni i analozi hipofize i hipotalamusa, somatotropin i agonisti somatotropina, ATK oznaka: H01AC03
English: Frequency not known (frequency cannot be estimated from the available data) Serious allergic reactions (anaphylaxis)
Croatian: Učestalost nepoznata (učestalost se ne može procijeniti iz dostupnih podataka) Ozbiljne alergijske reakcije (anafilaksija)
English: Insert the needle in the way the doctor showed you.
Croatian: Umetnite iglu na način kako Vam je liječnik pokazao.
English: Common: Skin hypertrophy, abnormal hair texture
Croatian: Često: hipertrofija kože, abnormalna tekstura kose
English: Very common (may affect more than 1 in 10 people) Low blood sugar (hypoglycaemia)
Croatian: Vrlo česte (mogu se javiti kod više od 1 na 10 osoba) Nizak šećer u krvi (hipoglikemija)
English: Pregnancy There are no or limited amount of data for the use of mecasermin in pregnant women.
Croatian: Ne postoje ili su ograničene količine podataka za primjenu mekasermina kod trudnica.
English: In adolescents with Primary IGFD and in healthy adults there were no apparent differences between males and females in the pharmacokinetics of INCRELEX.
Croatian: U adolescenata s teškom primarnom deficijencijom IGF i kod zdravih odraslih osoba nije bilo očitih razlika između muškaraca i žena u farmakokinetici INCRELEXA.
English: Of these, 72 (89%) had Laron syndrome-like phenotype; 7 (9%) had GH gene deletion, 1 (1%) had neutralizing antibodies to GH and 1 (1%) had isolated genetic GH deficiency.
Croatian: Od toga, 72 (89%) imalo je fenotip sličan Laronovom sindromu; 7 (9%) imalo je deleciju gena za hormon rasta, 1 (1%) je imao antitijela koja neutraliziraju hormon rasta, a 1 (1%) je imao izolirani genetski nedostatak hormona rasta.
English: The most frequently reported adverse reactions from the clinical trials were headache (44%), hypoglycaemia (28%), vomiting (26%), injection site hypertrophy (17%), and otitis media (17%).
Croatian: Najčešće prijavljene nuspojave iz kliničkih ispitivanja bile su su glavobolja (44%), hipoglikemija (28%), povraćanje (26%), hipertrofija na mjestu injiciranja (17%) i otitis media (17%)
English: MARKETING AUTHORISATION NUMBER(S) EU/1/07/402/001
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/07/402/001
English: Do not use after the expiry date (which is stated on the label after EXP and it refers to the last day of the month) or if it is cloudy or if you see bits.
Croatian: Nemojte ju koristiti nakon isteka roka valjanosti (koji je naveden iza oznake „Rok valjanosti“ ili EXP i odnosi se na posljednji dan navedenog mjeseca) ili ako je zamućena i vidite čestice.
English: Figure 6: Remove air bubbles and refill syringe
Croatian: Slika 6: Uklonite mjehuriće zraka i ponovno napunite štrcaljku
English: What INCRELEX contains - The active substance is mecasermin.
Croatian: Što INCRELEX sadrži - Djelatna tvar je mekasermin.
English: The doctor or nurse will instruct you how to give the injection.
Croatian: Liječnik ili medicinska sestra uputit će vas kako dati injekciju.
English: [1] P-values for comparison versus pre-Tx values were computed using paired t-tests.
Croatian: [1] P-vrijednosti za usporedbu naspram pre-Tx vrijednosti izračunate su pomoću sparenih t-testova.
English: If bubbles are in the syringe, hold the vial and syringe with needle straight up and tap the side of the syringe until the bubbles float to the top.
Croatian: Ako ima mjehurića u štrcaljki, držite bočicu i štrcaljku s iglom okrenutom ravno prema gore i lupnite stranu štrcaljke dok mjehurići ne počnu plutati na vrhu.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 03 August 2007
Croatian: Datum prvog odobrenja: 03. kolovoz 2007.
English: If hypoglycaemia occurs with recommended doses, despite adequate food intake, the dose should be reduced.
Croatian: Ako s preporučenim dozama dođe do hipoglikemije, unatoč adekvatnom unosu hrane, dozu treba smanjiti.
English: • Exclusion of secondary forms of IGF-1 deficiency, such as malnutrition, hypothyroidism, or chronic treatment with pharmacologic doses of anti-inflammatory steroids.
Croatian: • Isključenjem sekundarnih oblika deficijencije IGF-1, kao što su malnutricija, hipotireoza ili kroničnog liječenja farmakološkim dozama protuupalnih steroida.
English: Leave the syringe in the vial and turn both upside down.
Croatian: Ostavite štrcaljku u bočici i okrenite oboje naopako.
English: Pre-treatment height velocity data were available for 75 subjects.
Croatian: Podaci o brzini rasta prije liječenja dostupni su za 75 ispitanika.
English: Oral glucose or food should be consumed.
Croatian: Potrebno je oralno uzimati glukozu ili hranu.
English: Severe Primary IGFD is defined by:
Croatian: Teška primarna deficijencija IGF definira se pomoću:
English: Breast-feeding while taking INCRELEX is not recommended, because there is insufficient information on the excretion of mecasermin in human milk.
Croatian: Dojenje se ne preporučuje tijekom uzimanja INCRELEXA zato što nema dovoljno informacija o izlučivanju mekasermina u majčino mlijeko.
English: Talk to your doctor or pharmacist before using INCRELEX - if you have a curved spine (scoliosis).
Croatian: Obratite se svom liječniku ili ljekarniku prije primjene INCRELEXA, - ako imate iskrivljenu kralježnicu (skoliozu).
English: The dose should be individualised for each patient.
Croatian: Dozu treba prilagoditi za svakog bolesnika.
English: If you develop any of these events, please follow the advice given for each event in the sections below.
Croatian: Ako Vam se pojavi bilo koja nuspojava, molimo postupajte prema savjetima, navedenima u tekstu koji slijedi, za svaku nuspojavu.
English: Limited information is available on the concentration of unbound IGF-1 after the administration of INCRELEX.
Croatian: Dostupne su ograničene informacije o koncentraciji nevezanog IGF-1 nakon primjene INCRELEXA.
English: IGF-1 has mitogenic activity that leads to an increased number of cells in the body.
Croatian: IGF-1 ima mitogeno djelovanje koje vodi do povećanog broja stanica u tijelu.
English: Do not use INCRELEX - if you are allergic to mecasermin or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte primjenjivati INCRELEX - ako ste alergični na mekasermin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.). - ako imate rak.
English: If the recommended dose is not tolerated by the patient, treatment with a lower dose can be considered.
Croatian: Ako bolesnik ne tolerira preporučenu dozu, može se razmotriti liječenje manjom dozom.
English: Figure 3: Prepare for extraction
Croatian: Slika 3: Pripremite za vađenje
English: In blood, IGF-1 is bound to six IGF binding proteins (IGFBPs), with ~80% bound as a complex with IGFBP-3 and an acid-labile subunit.
Croatian: U krvi, IGF-1 se vezuje na šest IGF veznih proteina (IGFBP), s ~80% vezanim kao kompleks s IGFBP-3 i kiselinsko-labilna podjedinica.
English: • Instructions to change and rotate the site of injection for each injection to avoid the development of lipohypertrophy.
Croatian: • Upute za promjenu i rotiranje mjesta injiciranja za svaku injekciju radi izbjegavanja razvoja lipohipertrofije.
English: A small number of cases indicative of anaphylaxis requiring hospitalisation have been reported.
Croatian: Prijavljen je mali broj slučajeva koji su upućivali na anafilaksiju koja je zahtijevala hospitalizaciju.
English: Mecasermin therapy should be discontinued if pregnancy occurs.
Croatian: Liječenje mekaserminom treba prekinuti ako dođe do trudnoće.
English: When injections were properly dispersed, the condition resolved.
Croatian: Kada su mjesta injiciranja bila pravilno raspoređena, smetnje su se povukle.
English: What INCRELEX is and what it is used for
Croatian: Što je INCRELEX i za što se koristi
English: As INCRELEX contains benzyl alcohol, it must not be given to premature babies or neonates.
Croatian: Kako INCRELEX sadrži benzilni alkohol, ne smije se davati prijevremeno rođenoj dojenčadi ili novorođenčadi.
English: The rhIGF-1 protein is synthesised in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1.
Croatian: Protein rhIGF-1 sintetiziran je u bakteriji (E. coli) koja je modificirana dodatkom gena za ljudski IGF-1.
English: Patients with abnormal echocardiogram findings or cardiovascular symptoms should be followed regularly with echocardiogram procedures.
Croatian: Bolesnike s abnormalnim nalazima ehokardiograma ili kardiovaskularnim simptomima treba redovito kontrolirati ehokardiografijom.
English: Tell the doctor if you develop hearing problems.
Croatian: Obavijestite liječnika ako osjetite probleme sa sluhom.
English: In some patients treated with mecasermin, an ultrasound examination of the heart (echocardiogram) showed an increased size of the heart muscle and abnormalities of heart valve function.
Croatian: Kod nekih bolesnika liječenih mekaserminom, ultrazvučni pregled srca (ehokardiogram) pokazao je povećanu veličinu srčanog mišića i poremećaji funkcije srčanog zaliska.
English: Organ growth: treatment of IGF-1 deficient rats with rhIGF-1 results in whole body and organ growth.
Croatian: Rast organa: liječenje nedostatka IGF-1 kod štakora s rhIGF-1 rezultira rastom cijelog tijela i organa.
English: If the solution is cloudy, or contains particulate matter, it must not be injected.
Croatian: Ako je otopina mutna ili sadrži čestice, ne smije se injicirati.
English: - if you develop a limp or hip or knee pain - if you have enlarged tonsils (tonsillar hypertrophy).
Croatian: - ako vam se razvije šepanje ili bol u kuku ili koljenu, - ako imate uvećane krajnike (hipertrofija tonzila).
English: Precaution to be taken before manipulating or administering the medicinal product The solution should be clear immediately after removal from the refrigerator.
Croatian: Mjere opreza koje treba poduzeti prije rukovanja lijekom ili njegove primjene Otopina treba biti bistra odmah nakon vađenja iz hladnjaka.
English: Benzyl alcohol may cause toxic reactions and anaphylactoid reactions in infants and children up to 3 years old.
Croatian: Benzilni alkohol može prouzročiti toksične reakcije i anafilaktoidne reakcije kod dojenčadi i djece u dobi do 3 godine.
English: • To perform a routine funduscopic examination prior to beginning treatment and periodically during treatment or at the occurrence of clinical symptoms.
Croatian: • Da obave rutinski fundoskopski pregled prije započinjanja liječenja i periodično za vrijeme liječenja ili pri pojavi kliničkih simptoma.
English: It is also recommended that all women of childbearing potential use adequate contraception during treatment.
Croatian: Preporučuje se također da sve žene u generativnoj dobi koriste odgovarajuću kontracepciju tijekom liječenja.
English: Patients who terminate treatment should also have an echocardiogram.
Croatian: Bolesnici koji prekidaju liječenje također trebaju obaviti ehokardiogram.
English: The height velocities at a given year of treatment were compared by paired t-tests to the pre-treatment height velocities of the same subjects completing that treatment year.
Croatian: Brzine rasta u određenoj godini liječenja bile su uspoređivane sparenim t-testom s brzinom rasta istog ispitanika prije početka liječenja koji je dovršio liječenje u toj godini.
English: For the 21 treatment naïve subjects with near-adult height, the mean (± SD) of the difference between observed increase in height versus that expected from Laron was approximately 13 cm (± 8 cm) after an average of 11 years of treatment.
Croatian: Za 21 ispitanika visine blizu odrasloj dobi, koji nije prethodno liječen, srednja vrijednost (± SD) razlike između uočenog porasta u visini naspram očekivanog prema Laronu, bila je približno 13 cm (± 8 cm) nakon prosječno 11 godina liječenja.
English: • The signs and symptoms of hypoglycaemia.
Croatian: • Znakovi i simptomi hipoglikemije.
English: During clinical trials in other indications totalling approximately 300 patients, reports of local and/or systemic hypersensitivity were received for 8% of patients.
Croatian: Za vrijeme kliničkih ispitivanja drugih indikacija ukupno u približno 300 bolesnika, prijave o lokalnoj i/ili sistemskoj preosjetljivosti primljene su za 8% bolesnika.
English: What INCRELEX is and what it is used for 2.
Croatian: Što je INCRELEX i za što se koristi 2.
English: Under normal circumstances, growth hormone (GH) binds to its receptor in the liver and other tissues, and stimulates the synthesis/secretion of IGF-1.
Croatian: U normalnim okolnostima hormon rasta vezuje se za svoj receptor u jetri i drugim tkivima, i stimulira sintezu/lučenje IGF1.
English: The physician information about INCRELEX should contain the following key elements:
Croatian: Informacije za liječnika o INCRELEXU trebaju sadržavati sljedeće ključne elemente:
English: Mecasermin should not be used for growth promotion in patients with closed epiphyses.
Croatian: Mekasermin se ne bi smjelo koristiti za poticanje rasta u bolesnika sa zatvorenim epifizama.
English: INCRELEX should be administered using sterile disposable syringes and injection needles which could be provided by your doctor, pharmacist or nurse.
Croatian: INCRELEX treba primjenjivati pomoću jednokratne sterilne štrcaljke i igala za injekcije, koje mogu osigurati liječnik, ljekarnik ili medicinska sestra.
English: Parents and patients should be informed that such reactions are possible and that if a systemic allergic reaction occurs, treatment should be interrupted and prompt medical attention should be sought.
Croatian: Roditelji i bolesnici trebaju biti informirani da su takve reakcije moguće i ako se dogodi sistemska alergijska reakcija, treba prekinuti liječenje i potražiti brzu medicinsku pomoć.
English: Therefore, this medicinal product is not recommended in children below age of 2.
Croatian: Stoga se primjena ovog lijeka ne preporučuje kod djece u dobi ispod 2 godine.
English: Slowly push in the plunger of the syringe all the way, making sure you have injected all the liquid.
Croatian: Polako gurajte klip štrcaljke do kraja, pazeći da ubrizgate svu tekućinu.
English: If a dose is skipped, the next dose should not be made larger to compensate.
Croatian: Ako se doza preskoči, sljedeća doza ne smije biti uvećana kako biste nadoknadili propuštenu.
English: INCRELEX contains benzyl alcohol as a preservative which may cause toxic reactions and allergic reactions in infants and children up to 3 years old.
Croatian: INCRELEX sadrži benzilni alkohol kao konzervans, što može izazvati toksične i alergijske reakcije kod dojenčadi i djece u dobi do 3 godine.
English: INCRELEX contains benzyl alcohol and sodium
Croatian: INCRELEX sadrži benzilni alkohol i natrij
English: There were also reports of local allergic reactions at the injection site.
Croatian: Također je bilo prijava o lokalnim alergijskim reakcijama na mjestu injiciranja.
English: Excess mortality secondary to IGF-1 induced hypoglycaemia was observed in the carcinogenesis studies.
Croatian: Pretjerana smrtnost, posljedično IGF-1 induciranoj hipoglikemiji, zabilježena je u ispitivanjima karcinogeneze.
English: Hypoglycaemia was the most frequently reported adverse event and a proper attention has to be given to meals in relation to dosing.
Croatian: Najčešće prijavljivani štetni događaj bila je hipoglikemija i zato je potrebno posvetiti odgovarajuću pozornost prehrani u odnosu na doziranje.
English: 6.6 Special precautions for disposal and other handling INCRELEX is supplied as a multi-dose solution.
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom INCRELEX se isporučuje kao višedozna otopina.