FrancophonIA/ELRC3.0 huggingface dataset:
English: The metabolic pathway of elotuzumab has not been characterized.
Croatian: Put metabolizma elotuzumaba nije okarakteriziran.
English: Lenalidomide and pomalidomide are expected to be harmful for an unborn baby.
Croatian: Očekuje se da će lenalidomid i pomalidomid biti štetni za nerođeno dijete.
English: No dose adjustment is required for Empliciti in patients over 65 years of age (see section 5.2).
Croatian: Nije potrebno prilagođavati dozu lijeka Empliciti u bolesnika starijih od 65 godina (vidjeti dio 5.2).
English: More than one vial of Empliciti may be needed to give the total dose for the patient.
Croatian: Možda će biti potrebno više od jedne bočice lijeka Empliciti da bi se bolesniku dala ukupna doza.
English: Pharmacokinetic interaction studies have not been conducted.
Croatian: Nisu provedena ispitivanja farmakokinetičkih interakcija.
English: The median OS in the E-Ld arm was 48.30 months compared with 39.62 months in the Ld arm.
Croatian: Medijan OS-a u E-Ld skupini bio je 48,30 mjeseci u usporedbi s 39,62 mjeseca u Ld skupini.
English: The powder is white to off white whole or fragmented cake.
Croatian: Prašak je bijel do bjelkast cjelovit ili razlomljeni kolačić.
English: Non-clinical safety information primarily consists of limited in vitro human cell/tissue studies where no safety findings were identified.
Croatian: Neklinički podaci o sigurnosti prvenstveno se sastoje od ograničenih ispitivanja na ljudskim stanicama/tkivu in vitro, u kojima nisu pronađeni nikakvi sigurnosni problemi.
English: Neutralizing antibodies were detected in 2 of 53 patients.
Croatian: Neutralizirajuća protutijela pronađena su u 2 od 53 bolesnika.
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached.
Croatian: • prilikom i svake izmjene sustava za upravljanje rizikom, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik, odnosno kada je izmjena rezultat ostvarenja nekog važnog cilja (u smislu farmakovigilancije ili minimizacije rizika).
English: Rate (incidence rate/100 patient years)
Croatian: Stopa (stopa incidencije/1 00 bolesnikgodina)
English: Avoid vigorous agitation, DO NOT SHAKE.
Croatian: Izbjegavajte žustro mućkanje, NEMOJTE TRESTI BOČICU.
English: A pre-specified analysis for 3-year PFS rate was performed based on a minimum follow-up time of 33 months.
Croatian: Unaprijed specificirana analiza za 3-godišnju stopu PFS-a provedena je na temelju minimalnog vremena praćenja od 33 mjeseca.
English: Patients experiencing infusion reactions should be advised not to drive and use machines until symptoms abate.
Croatian: Bolesnicima u kojih se pojave reakcije na infuziju treba savjetovati da ne upravljaju vozilima i ne rade sa strojevima dok se simptomi ne povuku.
English: Regardless of the subgroup evaluated, PFS was generally consistent with that observed in the ITT population for the treatment groups.
Croatian: Neovisno o podskupini koja se ocjenjivala, PFS je u načelu bio u skladu s onim opaženim u ITT populaciji za liječene skupine.
English: The patient had no symptoms, did not require any treatment for the overdose, and was able to continue on elotuzumab therapy.
Croatian: Bolesnik nije pokazivao nikakve simptome, nije mu bilo potrebno liječenje zbog predoziranja te je mogao nastaviti terapiju elotuzumabom.
English: Response to therapy Relapsed
Croatian: Odgovor na terapiju Relapsni
English: European Group for Blood and Marrow Transplantation (EBMT) criteria.
Croatian: European Group for Blood and Marrow Transplatation).
English: * Continue this rate until infusion is completed.
Croatian: * Nastaviti primjenu tom brzinom sve do završetka infuzije.
English: Neutralizing antibodies were detected in 19 of 299 patients in CA204004.
Croatian: Neutralizirajuća protutijela pronađena su u 19 od 299 bolesnika u ispitivanju CA204004.
English: As Empliciti will be given to you by a healthcare professional, it is unlikely you will be given too much.
Croatian: Budući da će Vam ovaj lijek davati zdravstveni radnik, nije vjerojatno da ćete primiti preveliku dozu.
English: Each vial contains a slight overfill to ensure sufficient extractable volume.
Croatian: Svaka bočica sadrži malo lijeka u suvišku, kako bi se osigurao dostatan volumen za izvlačenje.
English: Efficacy results are presented in Table 8 and Figure 1.
Croatian: Rezultati za djelotvornost prikazani su u Tablici 8 i na Slici 1.
English: Absorption Elotuzumab is dosed via intravenous route and therefore is immediately and completely bioavailable.
Croatian: Elotuzumab se primjenjuje intravenskim putem i stoga je njegova bioraspoloživost trenutačna i potpuna.
English: However, if you get an infusion reaction (fever, chills, high blood pressure see section 4 “Possible side effects”), do not drive, cycle or use machines until the reaction stops.
Croatian: Međutim, ako se pojavi reakcija na infuziju (vrućica, zimica, visok krvni tlak; pogledajte dio 4. "Moguće nuspojave"), nemojte upravljati vozilima niti raditi sa strojevima dok se reakcija ne povuče.
English: The pre-planned final OS analysis was performed after 212 deaths in the E-Ld arm and 225 deaths in the Ld arm.
Croatian: Unaprijed planirana konačna analiza OS-a napravljena je nakon 212 smrtnih slučajeva u E-Ld skupini i 225 smrtnih slučajeva u Ld skupini.
English: Number of subjects at risk
Croatian: Broj ispitanika pod rizikom
English: You should not use Empliciti if you are pregnant, unless your doctor specifically recommends it.
Croatian: Ne smijete primati Empliciti ako ste trudni, osim ako Vam to izričito ne preporuči Vaš liječnik.
English: Empliciti is taken in treatment cycles that are 28 days (4 weeks) long in combination with other medicines used to treat multiple myeloma.
Croatian: Empliciti se primjenjuje u ciklusima liječenja koji traju 28 dana (4 tjedna), u kombinaciji s drugim lijekovima koji se koriste za liječenje multiplog mijeloma.
English: The maximum infusion rate should not exceed 5 mL/min.
Croatian: Najveća brzina infuzije ne smije premašiti 5 ml/min.
English: There is no human experience with elotuzumab during pregnancy.
Croatian: Nema iskustva s primjenom elotuzumaba tijekom trudnoće u ljudi.
English: Other medicines and Empliciti Tell your doctor if you are taking, have recently taken, or might take any other medicines.
Croatian: Obavijestite svog liječnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: Absence of del17p Presence of t(4;14) Absence of t(4;14) ISS Stage I
Croatian: Odsutnost del17p Prisutnost t(4;14) Odsutnost t(4;14) Stadij prema ISS klasifikaciji I
English: If the infusion reaction recurs, the Empliciti infusion must be stopped and not restarted on that day (see section 4.4).
Croatian: Ako se reakcija na infuziju ponovno pojavi, infuzija lijeka Empliciti mora se prekinuti i ne smije se ponovno započeti tog dana (vidjeti dio 4.4).
English: Final volume of reconstituted Empliciti in the vial (including volume displaced by the solid cake)
Croatian: Konačan volumen rekonstituiranog lijeka Empliciti u bočici (uključujući volumen koji je istisnuo čvrsti kolačić)
English: As with all therapeutic proteins, there is a potential for immunogenicity to Empliciti.
Croatian: Kao i svi terapijski proteini, Empliciti može imati imunogeno djelovanje.
English: Dose delay, interruption, or discontinuation
Croatian: Odgoda, privremeni prekid ili trajna obustava primjene
English: This 8-hour period should be inclusive of the product administration period.
Croatian: Navedeno 8-satno razdoblje mora uključivati i razdoblje primjene lijeka.
English: The most serious adverse reaction that may occur during elotuzumab treatment is pneumonia.
Croatian: Najozbiljnija nuspojava koja se može javiti tijekom liječenja elotuzumabom je pneumonija.
English: Because elotuzumab does not recognize non-human forms of SLAMF7 protein, in vivo safety data from animal studies are irrelevant.
Croatian: Budući da elotuzumab ne prepoznaje oblike proteina SLAMF7 koji nisu ljudskog podrijetla, in vivo sigurnosni podaci iz ispitivanja na životinjama nisu relevantni.
English: Tell your doctor or nurse straight away if you feel unwell during infusion.
Croatian: Odmah se obratite svom liječniku ili medicinskoj sestri ako se tijekom infuzije budete osjećali loše.
English: Investigator Assessed
Croatian: Ocjena ispitivača
English: Male patients must use effective contraception measures during and for 180 days following treatment if their partner is pregnant or of childbearing potential and not using effective contraception.
Croatian: Bolesnici muškog spola moraju koristiti učinkovite mjere kontracepcije tijekom i još 180 dana nakon liječenja ako im je partnerica trudna ili je žena reproduktivne dobi koja ne koristi učinkovitu kontracepciju.
English: Overall survival (OS) was a secondary endpoint with the pre-planned final OS analysis to occur after at least 427 deaths.
Croatian: Ukupno preživljenje (eng. overall survival OS) bio je sekundarna mjera ishoda s unaprijed planiranom konačnom analizom OS nakon najmanje 427 smrtnih slučajeva.
English: A slight back pressure may be experienced during administration of the water for injections, which is considered normal.
Croatian: Možda ćete osjetiti blagi otpor pri ubrizgavanju vode za injekcije, što se smatra normalnim.
English: The European Medicines Agency has waived the obligation to submit the results of studies in all subsets of the paediatric population in treatment of multiple myeloma (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove je izuzela obvezu podnošenja rezultata ispitivanja u svim podskupinama pedijatrijske populacije za liječenje multiplog mijeloma (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Do not stop treatment unless you have discussed this with your doctor.
Croatian: Nemojte prekinuti liječenje bez prethodnog razgovora sa svojim liječnikom.
English: Stopping your treatment with Empliciti may stop the effect of the medicine.
Croatian: Prekid liječenja lijekom Empliciti mogao bi zaustaviti učinak lijeka.
English: Thus, the effect of elotuzumab on male and female fertility is unknown.
Croatian: Stoga je učinak elotuzumaba na plodnost muškaraca i žena nepoznat.
English: This leaflet is available in all EU/EEA languages on the European Medicines Agency website.
Croatian: Ova Uputa o lijeku je dostupna na svim jezicima EU-a /EGP-a na internetskim stranicama Europske agencije za lijekove.
English: Grade 3 infusion reactions occurred in 1% of patients.
Croatian: Reakcije na infuziju 3. stupnja nastupile su u 1% bolesnika.
English: The final OS analysis met the protocol-specified boundary for statistical significance (p ≤ 0.046).
Croatian: Konačna analiza OS-a dosegla je protokolom specificiranu graničnu vrijednost OS-a za statistički značajnost (p ≤
English: Elotuzumab only recognizes human SLAMF7 protein.
Croatian: Elotuzumab prepoznaje samo ljudski protein SLAMF7.
English: When the symptoms go away or improve, the infusion can be continued more slowly and speeded up gradually if the symptoms do not recur.
Croatian: Nakon što se simptomi povuku ili ublaže, infuzija se može nastaviti manjom brzinom, koja se zatim može postupno povećavati ako se simptomi ponovno ne pojave.
English: Depending on the seriousness of the infusion reactions, you may require additional treatment to prevent complications and reduce your symptoms, or your infusion of Empliciti may be interrupted.
Croatian: Ovisno o ozbiljnosti reakcija na infuziju, možda će Vam biti potrebno dodatno liječenje kako bi se spriječile komplikacije i ublažili simptomi, ili će se primjena infuzije lijeka Empliciti možda privremeno prekinuti.
English: The rate of infusion reactions was much higher in patients who were not premedicated.
Croatian: Stopa reakcija na infuziju bila je mnogo veća u bolesnika koji nisu primili premedikaciju.
English: Uncommon (may affect up to 1 in 100 people) Sudden life-threatening allergic reaction (anaphylactic reaction)
Croatian: Manje česte (mogu se javiti u do 1 na 100 osoba) iznenadna alergijska reakcija opasna po život (anafilaktička reakcija)
English: A pre-specified final analysis for OS was performed based on at least 427 deaths with a minimum follow-up time of 70.6 months.
Croatian: Unaprijed specificirana konačna analiza za OS provedena je na najmanje 427 smrtnih slučaja s minimalnim vremenom praćenja od 70,6 mjeseci.
English: It is not known, whether elotuzumab passes into breast milk or if there is any risk to the breast-fed infant.
Croatian: Nije poznato izlučuje li se elotuzumab u majčino mlijeko i postoji li ikakav rizik za dojenče.
English: * Elotuzumab is produced in NS0 cells by recombinant DNA technology.
Croatian: * Elotuzumab se proizvodi tehnologijom rekombinantne DNK u stanicama NS0.
English: Do not store any unused portion of the infusion solution for reuse.
Croatian: Neiskorišteni dio otopine za infuziju nemojte čuvati za ponovnu primjenu.
English: In case of detection of additional peaks on serum immunofixation, the possibility of a biclonal gammopathy should be excluded.
Croatian: U slučaju detekcije dodatnih pikova kod imunofiksacije u serumu, potrebno je isključiti mogućnost biklonske gamapatije.
English: When lenalidomide is used, particular attention to pregnancy testing and prevention requirements is needed (see “Pregnancy and breast-feeding” in this section).
Croatian: Kada se primjenjuje lenalidomid, potrebno je posvetiti posebnu pozornost zahtjevima za testiranje na trudnoću i sprječavanje trudnoće (pogledajte odlomak "Trudnoća i dojenje" u ovom dijelu).
English: [6.54, NE]
Croatian: [6,54; NO]
English: Time interval
Croatian: Vremenski interval
English: Table 1: Reconstitution instructions
Croatian: Tablica 1: Upute za rekonstituciju
English: Table 12: Reconstitution instructions Strength
Croatian: Tablica 12: Upute za rekonstituciju Jačina
English: Method of administration Empliciti is for intravenous use only.
Croatian: Način primjene Empliciti je namijenjen samo za intravensku primjenu.
English: Your doctor will continue to treat you with Empliciti for as long as the disease improves or remains stable and side effects are tolerable.
Croatian: Liječnik će Vas nastaviti liječiti lijekom Empliciti sve dok Vam se stanje poboljšava ili je bolest stabilna i dok podnosite nuspojave.
English: You will be monitored for signs of such effects during and after the infusion.
Croatian: Bit ćete pod nadzorom tijekom i nakon infuzije kako bi se uočili mogući znakovi tih učinaka.
English: A statistically significant advantage in OS was observed in patients in the E-Ld arm compared to patients in the Ld arm.
Croatian: Statistički značajna prednost u OS-u bila je primijećena u bolesnika u E-Ld skupini u usporedbi s Ld skupinom.
English: Elotuzumab will be given in combination with lenalidomide, which is contraindicated during pregnancy.
Croatian: Elotuzumab će se primjenjivati u kombinaciji s lenalidomidom, koji je kontraindiciran tijekom trudnoće.
English: In these 19 patients, anti-product antibodies occurred within the first 2 months of the initiation of Empliciti treatment.
Croatian: U tih su se 19 bolesnika protutijela na lijek pojavila unutar prva 2 mjeseca nakon uvođenja lijeka Empliciti.
English: This interference can impact the determination of complete response and possibly relapse from complete response in patients with IgG kappa myeloma protein.
Croatian: Ta interferencija može utjecati na određivanje potpunog odgovora i potencijalno relapsa nakon potpunog odgovora u bolesnika s mijelomskim proteinom IgG kapa.
English: Premedication Empliciti (mg/kg) intravenously Pomalidomide (4 mg) orally
Croatian: Premedikacija Empliciti (mg/kg) intravenski Pomalidomid (4 mg) peroralno
English: Cycle 1, Dose 3 and 4 and all subsequent Cycles
Croatian: 1. ciklus, 3. i 4. doza i svi sljedeći ciklusi
English: There is no relevant use of Empliciti in the paediatric population for the indication of multiple myeloma.
Croatian: Nema relevantne primjene lijeka Empliciti u pedijatrijskoj populaciji za indikaciju multiplog mijeloma.
English: Elotuzumab therapy should be initiated and supervised by physicians experienced in the treatment of multiple myeloma.
Croatian: Terapiju elotuzumabom trebaju započeti i nadzirati liječnici s iskustvom u liječenju multiplog mijeloma.
English: Second Primary Malignancies
Croatian: Druge primarne zloćudne bolesti
English: Patients had to recover after transplant for a minimum of 12 weeks from autologous stem cell transplant (SCT), and 16 weeks from allogeneic SCT.
Croatian: Bolesnici su se morali oporavljati nakon presađivanja tijekom najmanje 12 tjedana nakon presađivanja autolognih matičnih stanica te 16 tjedana nakon presađivanja alogenih matičnih stanica.
English: If there is no recurrence of the infusion reaction, the escalation can be resumed (see Tables 3 and 4).
Croatian: Ako se reakcija na infuziju ne povrati, brzina infuzije može se nastaviti povećavati (vidjeti Tablice 3 i 4).
English: Empliciti is for single use only.
Croatian: Empliciti je namijenjen samo za jednokratnu primjenu.
English: If any medicine in the treatment is delayed, interrupted, or discontinued, your doctor will decide how your treatment should be continued.
Croatian: Ako se primjena bilo kojeg lijeka koji je dio terapije odgodi, privremeno prekine ili trajno obustavi, Vaš će liječnik odlučiti kako nastaviti liječenje.
English: Then invert the vial a few times in order to dissolve any powder that may be present on top of the vial or the stopper.
Croatian: Zatim nekoliko puta preokrenite bočicu kako bi se rastopio i prašak koji se možda nalazi na vrhu bočice ili na čepu.
English: However, if oral or intravenous dexamethasone is delayed or discontinued, the administration of Empliciti should be based on clinical judgment (e.g. risk of hypersensitivity) (see section 4.4).
Croatian: Međutim, ako se odgodi ili trajno obustavi peroralna ili intravenska primjena deksametazona, primjena lijeka Empliciti mora se temeljiti na kliničkoj procjeni (npr. riziku od preosjetljivosti) (vidjeti dio 4.4).
English: Empliciti powder for concentrate for solution for infusion (powder for concentrate) is a white to off white whole or fragmented cake provided in a glass vial.
Croatian: Empliciti prašak za koncentrat za otopinu za infuziju (prašak za koncentrat) je bijel do bjelkast cjelovit ili razlomljeni kolačić koji dolazi u staklenoj bočici.
English: Chemical and physical in use stability of the reconstituted and diluted solution has been demonstrated for 24 hours at 2°C - 8°C and protected from light.
Croatian: Kemijska i fizička stabilnost rekonstituirane i razrijeđene otopine dokazana je tijekom 24 sata na temperaturi od 2°C do 8°C, zaštićena od svjetlosti.
English: If you become pregnant while using Empliciti, tell your doctor.
Croatian: Ako zatrudnite dok primate Empliciti, obavijestite o tome svog liječnika.
English: Demographics and baseline characteristics were well balanced between treatment arms.
Croatian: Demografske i početne značajke bile su dobro ujednačene među liječenim skupinama.
English: Probability progression free (%)
Croatian: Vjerojatnost preživljenja bez progresije bolesti (%)
English: The rate of haematologic malignancies were the same between the two treatment arms (1.6%).
Croatian: Stopa hematoloških zloćudnih bolesti bila je jednaka u obje liječene skupine (1,6%).
English: Target-mediated clearance of elotuzumab increased with higher serum M-protein concentrations.
Croatian: Klirens elotuzumaba posredovan ciljnim mjestom povećavao se s višim serumskim koncentracijama M-proteina.
English: Studies to evaluate the effect of elotuzumab on fertility have not been performed.
Croatian: Nisu provedena ispitivanja kojima bi se ocijenio učinak elotuzumaba na plodnost.
English: In the same line, no carcinogenicity data are available for elotuzumab in animals, nor were fertility and embryo-foetal toxicity studies performed.
Croatian: Sukladno tome, nisu dostupni ni podaci o kancerogenosti elotuzumaba u životinja niti su provedena ispitivanja plodnosti te embriofetalne toksičnosti.
English: UNIQUE IDENTIFIER - 2D BARCODE 2D barcode carrying the unique identifier included.
Croatian: 17. JEDINSTVENI IDENTIFIKATOR - 2D BARKOD <Sadrži 2D barkod s jedinstvenim identifikatorom.>
English: Empliciti should not be used during pregnancy unless the clinical condition of the woman requires treatment with elotuzumab.
Croatian: Empliciti se ne smije primjenjivati tijekom trudnoće osim ako kliničko stanje žene ne zahtijeva liječenje elotuzumabom.
English: H2 blocker: ranitidine (50 mg intravenous or 150 mg orally) or equivalent H2 blocker.
Croatian: Blokator H2 receptora: ranitidin (50 mg intravenski ili 150 mg peroralno) ili ekvivalentni blokator H2 receptora.
English: Vital signs should be monitored every 30 minutes for 2 hours after the end of the Empliciti infusion.
Croatian: Potrebno je kontrolirati vitalne znakove svakih 30 minuta tijekom 2 sata nakon završetka infuzije lijeka Empliciti.
English: How much Empliciti is given The amount of Empliciti you will be given will be calculated based on your body weight.
Croatian: Koliko lijeka Empliciti ćete primiti Količina lijeka Empliciti koju ćete primiti izračunat će se na temelju
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Croatian: Nositelj odobrenja obavljat će zadane farmakovigilancijske aktivnosti i intervencije detaljno objašnjene u dogovorenom Planu upravljanja rizikom (RMP), koji se nalazi u Modulu 1.8.2 Odobrenja za stavljanje lijeka u promet, te svim sljedećim dogovorenim ažuriranim verzijama RMP-a .
English: If not used immediately, the solution for infusion may be stored in the refrigerator (2 °C - 8 °C) for up to 24 hours.
Croatian: Ako se ne primijeni odmah, otopina za infuziju može se čuvati u hladnjaku (2°C - 8°C) tijekom najviše 24 sata.
English: Complete response (CR) + stringent complete response (sCR).
Croatian: Potpuni odgovor (CR) + striktni potpuni odgovor (sCR).
English: The presence of elotuzumab in patient's serum may cause a small peak in the early gamma region on SPEP that is IgGƙ on serum immunofixation.
Croatian: Prisutnost elotuzumaba u serumu bolesnika mogla bi uzrokovati maleni pik u ranoj gama regiji kod SPEP-a, odnosno IgGƙ kod imunofiksacije u serumu.
English: The solution for infusion may be stored for a maximum of 8 hours of the total 24 hours at 20°C − 25°C and room light.
Croatian: Otopina za infuziju može se čuvati tijekom najviše 8 sati od ukupnog 24-satnog razdoblja na temperaturi od 20°C do 25°C i pri sobnoj svjetlosti.
English: Patients in the E-Ld arm had an 18% reduction in the risk of death compared with those in the Ld arm (HR = 0.82; 95.4% CI: 0.68, 1.00; p-value = 0.0408).
Croatian: Bolesnici u E-Ld skupini imali su 18% smanjen rizik od smrti u usporedbi s onima u Ld skupini (HR = 0,82; 95.4% CI: 0.68, 1,00; p-vrijednost = 0,0408).
English: The primary endpoint was investigator assessed PFS by modified International Myeloma Working Group (IMWG) criteria.
Croatian: Primarna mjera ishoda bio je PFS prema ocjeni ispitivača na temelju modificiranih kriterija Međunarodne radne skupine za mijelom (engl.
English: Empliciti is unlikely to affect your ability to drive or use machines.
Croatian: Nije vjerojatno da će Empliciti utjecati na Vašu sposobnost upravljanja vozilima ili rada sa strojevima.
English: Mood changes
Croatian: Promjena raspoloženja
English: Elotuzumab attaches to a target protein called SLAMF7.
Croatian: Elotuzumab se pričvršćuje za ciljni protein koji se zove SLAMF7.
English: In cycles 1 and 2, once weekly on days 1, 8, 15, and 22.
Croatian: U 1. i 2. ciklusu jedanput na tjedan, 1., 8., 15. i 22. dana.
English: Dexamethasone was administered on day 1, 8, 15 and 22 of each cycle.
Croatian: Deksametazon se primjenjivao 1., 8., 15. i 22. dana svakog ciklusa.