FrancophonIA/ELRC3.0 huggingface dataset:
English: Benazepril hydrochloride is a prodrug hydrolysed in vivo into its active metabolite, benazeprilat.
Slovenian: Benazeprilijev hidroklorid je prekurzor, ki se hidrolizira in vivo v aktiven metabolit, benazeprilat.
English: Benazeprilat is excreted via the biliary and the urinary route in dogs.
Slovenian: Benzaeprilat se izloča preko žolča in urina pri psih.
English: At steady state, mean Cmax of 324 μg/l and 66 μg/l are achieved for the primary metabolites, 7-α-thiomethyl-spironolactone and canrenone, 2 and 4 hours post-dosing, respectively.
Slovenian: V stabilnem stanju najvišjo Cmax 324 μg/l in 66 μg/l dosežeta primarna metabolita, 7-α-tiometil-spironolakton in kanrenon, v 2 in 4 urah po odmerjanju.
English: After multiple oral doses of 2 mg spironolactone per kg (with 0.25 mg benazepril hydrochloride per kg) for 7 consecutive days, no accumulation is observed.
Slovenian: Po večkratnih peroralnih odmerkih 2 mg spironolaktona na kg (z 0.25 mg benazeprilijevega hidroklorida na kg) 7 zaporednih dni, ni bilo opaziti akumulacije.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY NUMBER OF DOSES
Slovenian: VSEBINA, IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ODMERKOV 30 tablet
English: Do not use during pregnancy and lactation (see section "Pregnancy and lactation ").
Slovenian: Ne uporabite v obdobju brejosti in laktacije (glej poglavje ''Uporaba v obdobju brejosti, laktacije ali nesnosti'').
English: People with known hypersensitivity to spironolactone or benazepril should avoid contact with the product.
Slovenian: Osebe z znano preobčutljivostjo na benazepril ali spironolakton naj se izogibajo stiku z zdravilom za uporabo v veterinarski medicini.
English: Interaction with other medicinal products and other forms of interactionFurosemide has been used together with this combination of benazepril (hydrochloride) and spironolactone in dogs with heart failure without any clinical evidence of adverse interactions.
Slovenian: Medsebojno delovanje z drugimi zdravili in druge oblike interakcij Furosemid je bil uporabljen v kombinaciji s benazeprilijevim hidrokloridom in spironolaktonom pri psih s srčnim popuščanjem brez pojava kliničnih znakov neželenega medsebojnega delovanja.
English: Unchanged benazepril and hydrophilic metabolites account for the remainder.
Slovenian: Preostanek sestavljajo nespremenjen benazepril in hidrofilni metaboliti.
English: 30 tablets 90 tablets
Slovenian: 90 tablet
English: EXP {month/year} Once opened, use within 6 months.
Slovenian: Načeto/odprto zdravilo porabite v 6 mesecih.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Slovenian: B POGOJI DOVOLJENJA ZA PROMET Z ZDRAVILOM TER OMEJITVE GLEDE OSKRBE IN UPORABE
English: Unlike in humans, an increased incidence of hyperkalaemia was not observed in clinical trials performed in dogs with this combination.
Slovenian: V nasprotju z ljudmi, pri kliničnih preizkusih s to kombinacijo ni bilo opaziti povečanega pojava hiperkaliemije pri psih.
English: EU/2/12/142/001(1 x 30 tablets, 2.5 mg/20 mg) EU/2/12/142/002 (1 x 90 tablets, 2.5 mg/20 mg) EU/2/12/142/003 (1 x 30 tablets, 5 mg/40 mg) EU/2/12/142/004 (1 x 90 tablets, 5 mg/40 mg) EU/2/12/142/005 (1 x 30 tablets, 10 mg/80 mg) EU/2/12/142/006 (1 x 90 tablets, 10 mg/80 mg)
Slovenian: ŠTEVILKA(E) DOVOLJENJ(A) ZA PROMET EU/2/12/142/001 (1 x 30 tablet, 2.5 mg/20 mg) EU/2/12/142/002 (1 x 90 tablet, 2.5 mg/20 mg) EU/2/12/142/003 (1 x 30 tablet, 5 mg/40 mg) EU/2/12/142/004 (1 x 90 tablet, 5 mg/40 mg) EU/2/12/142/005 (1 x 30 tablet, 10 mg/80 mg) EU/2/12/142/006 (1 x 90 tablet, 10 mg/80 mg)
English: After multiple oral doses of 0.25 mg benazepril hydrochloride per kg (with 2 mg spironolactone per kg) for 7 consecutive days, a peak benazeprilat concentration (Cmax of 52.4 ng/ml) is achieved with a Tmax of 1.4 h.
Slovenian: Po večkratnih peroralnih odmerkih 0.25 mg benazeprilijevega hidroklorida na kg (z 2 mg spironolaktona na kg) 7 zaporednih dni, je najvišja koncentracija benazeprila (Cmax 52,4 ng/ml) dosežena v Tmax 1,4 urah.
English: Kidney function and serum potassium levels should be evaluated before initiating the treatment with benazepril and spironolactone, especially in dogs which may suffer hypoadrenocorticism, hyperkalaemia or hyponatraemia.
Slovenian: Pred začetkom zdravljenja s benazeprilom in spironolaktonom, je potrebno oceniti delovanje ledvic in nivo serumskega kalija, še posebno pri psih, ki so lahko oboleli za hipoadrenokorticizmom, hiperkaliemijo ali hiponatriemijo.
English: 80 mg The tablets are brown coloured, palatable, oblong shaped with a score line and chewable.
Slovenian: Tablete so rjave, okusne, ovalne oblike, z zarezo in žvečljive.
English: There may be a dose related hypertrophy of the adrenal zona glomerulosa at high dose rates.In a field study conducted in dogs with chronic degenerative valvular disease 85.9% of dogs showed good compliance with treatment (≥ 90% of prescribed tablets successfully administered) over a three month period.
Slovenian: V terenski študiji, narejeni pri psih s kronično degenerativno boleznijo zaklopk, je 85,9% psov pokazalo dobro skladnost z zdravljenjem (≥90% predpisanih tablet je bilo uspešno odmerjenih) v obdobju treh mesecev.
English: Cardboard box of 1 bottle of 90 tablets
Slovenian: Kartonska škatla z 1 plastenko po 30 tablet Kartonska škatla z 1 plastenko po 90 tablet
English: Aldosterone promotes myocardial fibrosis, myocardial and vascular remodelling and endothelial dysfunction, although the precise mechanism of action is not yet clearly defined.
Slovenian: Čeprav natančen mehanizem delovanja še ni definiran, aldosteron pospešuje miokardialno fibrozo, miokardialno in vaskularno preoblikovanje in endotelialno disfunkcijo.
English: The concomitant administration of this veterinary medicinal product with other anti-hypertensive agents (e.g. calcium channel blockers, β-blockers or diuretics), anaesthetics or sedatives may potentially lead to additive hypotensive effects.
Slovenian: Sočasna uporaba tega zdravila za uporabo v veterinarski medicini z drugimi anti-hipertenzivnimi zdravili (npr. zaviralci kalcijevih kanalčkov, β zaviralci ali diuretiki), anestetiki ali sedativi lahko vodi do dodatnih hipotenzivnih učinkov.
English: STATEMENT OF ACTIVE SUBSTANCES
Slovenian: Seznam pomožnih snovi
English: The concomitant administration of this veterinary medicinal product with other potassium-sparing treatments (such as ß-blockers, calcium channels blockers, angiotensin receptor blockers) may potentially lead to hyperkalaemia (see section "Special precautions for use in animals").
Slovenian: Sočasna uporaba tega zdravila za uporabo v veterinarski medicini z drugimi zdravili, ki zadržujejo kalij (kot so ß zaviralci, zaviralci kalcijevih kanalčkov, zaviralci angiotenzin receptorjev) lahko vodi do hiperkaliemije (glej poglavje ''Posebni previdnostni ukrepi za uporabo pri živalih").
English: The concomitant administration of this veterinary medicinal product with other potassium-sparing treatments (such as ß-blockers, calcium channels blockers, angiotensin receptor blockers) may potentially lead to hyperkalaemia (see section 4.5).
Slovenian: Sočasna uporaba tega zdravila za uporabo v veterinarski medicini z drugimi zdravili, ki zadržujejo kalij (kot so ß zaviralci, zaviralci kalcijevih kanalčkov, zaviralci angiotenzin receptorjev) lahko vodi do hiperkaliemije (glej poglavje 4.5).
English: Bottle of 90 tablets
Slovenian: Plastenka po 90 tablet
English: Pharmacodynamic properties
Slovenian: Farmakodinamične lastnosti
English: Cardalis chewable tablets should be administered to the dog once a day at a dosage of 0.25 mg/kg bodyweight (bw) benazepril hydrochloride (HCl) and 2 mg/kg bodyweight spironolactone, according to the following dosage table.
Slovenian: Cardalis žvečljive tablete dajemo psom enkrat dnevno v odmerku 0.25 mg/kg telesne mase benazeprilijevega hidroklorida (HCl) in 2 mg/kg telesne mase (t.m.)
English: benazepril HCl 2.5 mg, spironolactone 20 mg benazepril HCl 5 mg, spironolactone 40 mg benazepril HCl 10 mg, spironolactone 80 mg
Slovenian: KOLIČINA ZDRAVILNE(IH) UČINKOVIN(E) benazeprili HCl 2,5 mg, spironolactonum 20 mg benazeprili HCl 5 mg, spironolactonum 40 mg benazeprili HCl 10 mg, spironolactonum 80 mg
English: Name and address of the manufacturers responsible for batch release
Slovenian: Ime in naslov izdelovalca(izdelovalcev) zdravila, odgovornega (odgovornih) za sprostitev serije
English: Do not use during pregnancy and lactation.Embryotoxic effects (foetal urinary tract malformation) were seen in trials of benazepril (as hydrochloride) with laboratory animals (rats) at maternally nontoxic doses.
Slovenian: Z laboratorijskimi študijami z benazeprilom (kot hidroklorid) na laboratorijskih živalih (podganah) so bili dokazani embriotoksični učinki (deformacija sečil plodu) pri odmerkih, ki niso toksični za mater.
English: Lot {number}
Slovenian: ŠTEVILKA SERIJE Lot {številka}
English: Spironolactone
Slovenian: Krospovidon
English: Chewable tablet.
Slovenian: FARMACEVTSKA OBLIKA Žvečljive tablete.
English: Cardalis 2.5 mg/20 mg tablets
Slovenian: Cardalis 2,5 mg/20 mg tablete
English: Do not use during pregnancy and lactation.Embryotoxic effects (foetal urinary tract malformation) were seen in trials of benazepril with laboratory animals (rats) at maternally non-toxic doses.
Slovenian: Z laboratorijskimi študijami z benazeprilom na laboratorijskih živalih (podganah) so bili dokazani embriotoksični učinki (deformacija sečil plodu) pri odmerkih, ki niso toksični za mater.
English: Repeated administration of benazepril leads to slight bioaccumulation of benazeprilat, steady state being achieved within few days.
Slovenian: Večkratno dajanje benazeprila vodi do rahle bioakumulacije benazeprilata.
English: The tablets can be divided into equal halves.
Slovenian: Rjave okusne ovalne žvečljive tablete z zarezo.. Tablete lahko razpolovimo na dva enaka dela.
English: Lactose monohydrate Cellulose microcrystalline Povidone K30
Slovenian: Celuloza, mikrokristalna
English: Cardalis 5 mg/40 mg tablets
Slovenian: Cardalis 5 mg/40 mg tablete
English: Cardalis 10 mg/80 mg tablets
Slovenian: Cardalis 10 mg/80 mg tablete
English: Keep out of the sight and reach of children.
Slovenian: Shranjujte nedosegljivo otrokom.
English: Ask your veterinary surgeon or pharmacist how to dispose of medicines no longer required.
Slovenian: Glede odstranjevanja zdravil, ki jih ne uporabljate več, se posvetujte z veterinarjem.
English: Reversible prostatic atrophy in entire male dogs treated with spironolactone was noted in a Target Animal Safety study at the recommended dose.
Slovenian: Pri nekastriranih samcih psov zdravljenih s spironolaktonom je pogosto opažena reverzibilna atrofija prostate.
English: 4.2 Indications for use, specifying the target species
Slovenian: 4.4 Posebna opozorila za vsako ciljno živalsko vrsto Jih ni.
English: SPECIAL WARNING(S)
Slovenian: POSEBNA OPOZORILA
English: Cardalis 2.5 mg/20 mg chewable tablets for dogs Cardalis 5 mg/40 mg chewable tablets for dogs Cardalis 10 mg/80 mg chewable tablets for dogs benazepril HCl/spironolactone
Slovenian: Cardalis 2,5 mg/20 mg žvečljive tablete za pse Cardalis 5 mg/40 mg žvečljive tablete za pse Cardalis 10 mg/80 mg žvečljive tablete za pse benazeprilijev HCl/spironolakton
English: Cardalis 2.5 mg/20 mg chewable tablets for dogs Cardalis 5 mg/40 mg chewable tablets for dogs Cardalis 10 mg/80 mg chewable tablets for dogs
Slovenian: NAVODILO ZA UPORABO Cardalis 2,5 mg/20 mg žvečljive tablete za pse Cardalis 5 mg/40 mg žvečljive tablete za pse Cardalis 10 mg/80 mg žvečljive tablete za pse
English: The bottles are fitted with childproof caps.
Slovenian: Plastenka ima zapiralo varno pred otroki.
English: Cardalis 10 mg/80 mg chewable tablets
Slovenian: Cardalis 10 mg/80 mg žvečljive tablete
English: Cardalis 5 mg/40 mg chewable tablets
Slovenian: Cardalis 5 mg/40 mg žvečljive tablete
English: Chewable tablet
Slovenian: FARMACEVTSKA OBLIKA Žvečljive tablete
English: Cardalis 2.5 mg/20 mg chewable tablets for dogs Benazepril hydrochloride 2.5 mg, spironolactone 20 mg Cardalis 5 mg/40 mg chewable tablets for dogs Benazepril hydrochloride 5 mg, spironolactone 40 mg Cardalis 10 mg/80 mg chewable tablets for dogs Benazepril hydrochloride 10 mg, spironolactone 80 mg
Slovenian: Cardalis 2,5 mg/20 mg žvečljive tablete za pse Cardalis 5 mg/40 mg žvečljive tablete za pse Cardalis 10 mg/80 mg žvečljive tablete za pse benazeprili HCl/spironolactonum
English: After coadministration of spironolactone (2 mg/kg bw) and benazepril hydrochloride (0.25 mg/kg bw) the terminal plasma half-lives (t½) were 7 hours and 6 hours for canrenone and 7-α-thiomethylspironolactone respectively.
Slovenian: je bil terminalni razpolovni plazemski čas (t½) 7 ur in 6 ur za kanrenon in 7-α-tiometil-spironolakton.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE Cardboard box of 1 bottle of 30 tablets
Slovenian: PODATKI NA STIČNI OZ. PRIMARNI OVOJNINI Plastenka po 30 tablet
English: BATCH NUMBER
Slovenian: Povidon K30
English: Pregnancy and lactation
Slovenian: OSKRBE IN UPORABE
English: Biotransformation
Slovenian: Metabolizem
English: What measures are being taken to ensure the safe and effective use of Stelara?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Stelara?
English: The first injection is followed by a further injection four weeks later, and then an injection every 12 weeks.
Slovenian: Prvi injekciji sledi nadaljnja injekcija štiri tedne pozneje, nato pa ena injekcija vsakih 12 tednov.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Stelara on 16 January 2009.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Stelara, veljavno po vsej Evropski uniji, izdala 16. januarja 2009.
English: The full EPAR for Stelara can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Stelara je na voljo na spletni strani agencije:ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: Most of these effects were considered mild and did not require treatment to be stopped.
Slovenian: Večina teh učinkov je bila blagih in zaradi njih ni bilo treba prekiniti zdravljenja.
English: Stelara is a medicine used to treat the following diseases:
Slovenian: Stelara je zdravilo za zdravljenje naslednjih obolenj:
English: EPAR summary for the public
Slovenian: Povzetek EPAR za javnost ustekinumab
English: This is a summary of the European public assessment report (EPAR) for Stelara.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Stelara.
English: A monoclonal antibody is a type of protein that has been designed to recognise and attach to a specific structure (called an antigen) in the body.
Slovenian: Monoklonsko protitelo je vrsta beljakovine, ki je bila zasnovana tako, da v telesu prepozna posebno strukturo (imenovano antigen) in se veže nanjo.
English: What benefits of Stelara have been shown in studies?
Slovenian: Kakšne koristi je zdravilo Stelara izkazalo v študijah?
English: The infusion lasts at least one hour and the dose depends on the patient's bodyweight.
Slovenian: Infundiranje traja najmanj eno uro, odmerek pa je odvisen od bolnikove telesne mase.
English: Ustekinumab attaches to two cytokines (messenger molecules) in the immune system called interleukin 12 and interleukin 23.
Slovenian: Ustekinumab se veže na dva citokina (sporočilni molekuli) v imunskem sistemu, imenovana interlevkin 12 in interlevkin 23.
English: The Agency's Committee for Medicinal Products for Human Use (CHMP) decided that Stelara's benefits are greater than its risks and recommended that it be approved for use in the EU.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) pri agenciji je zaključil, da so koristi zdravila Stelara večje od z njim povezanih tveganj, in priporočil, da se odobri za uporabo v EU.
English: The side effects of the medicine were considered tolerable and manageable.
Slovenian: Neželeni učinki zdravila so se šteli za znosne in obvladljive.
English: What is Stelara and what is it used for?
Slovenian: Kaj je zdravilo Stelara in za kaj se uporablja?
English: The company subsequently provided the longer-term results of the studies (after 5 years of treatment), and the results of a study comparing Stelara with etanercept (another medicine for psoriasis).
Slovenian: Družba je naknadno predložila dolgoročne rezultate študij (po petih letih zdravljenja) in rezultate študije, v kateri so zdravilo Stelara primerjali z etanerceptom (drugim zdravilom za zdravljenje psoriaze).
English: Stelara must not be used in patients who have an active infection that the doctor considers important.
Slovenian: Zdravila Stelara ne smejo uporabljati bolniki z aktivno okužbo, ki jo je zdravnik ocenil za resno.
English: However, patients in some studies had unexpected increases in problems affecting the heart and blood vessels and psychiatric problems such as depression which might be related to Stelara.
Slovenian: Kljub temu se je v nekaterih študijah pri bolnikih pojavil nepričakovan porast težav s srcem in ožiljem ter psihiatričnih težav, kot je depresija, kar bi lahko bilo povezano z uporabo zdravila Stelara.
English: Other information about Stelara
Slovenian: Druge informacije o zdravilu Stelara
English: By blocking their activity, ustekinumab reduces the activity of the immune system and the symptoms of the disease.
Slovenian: Ustekinumab z zaviranjem njunega delovanja zmanjšuje dejavnost imunskega sistema in blaži simptome bolezni.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Stelara have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in varnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Stelara upoštevati zdravstveni delavci in bolniki, so vključeni tudi v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo.
English: Why is Stelara approved?
Slovenian: Zakaj je bilo zdravilo Stelara odobreno?
English: Stelara is available as a solution for injection (45 and 90 mg) in vials or prefilled syringes and as a concentrate (130 mg) to make a solution for infusion (drip) into a vein.
Slovenian: Zdravilo Stelara je na voljo kot raztopina za injiciranje (45 in 90 mg) v vialah ali napolnjenih injekcijskih brizgah in kot koncentrat (130 mg) za pripravo raztopine za infundiranje (kapalne infuzije) v veno.
English: What are the risks associated with Stelara?
Slovenian: Kakšna tveganja so povezana z zdravilom Stelara?
English: It is not intended to provide practical advice on how to use Stelara.
Slovenian: Povzetek ni namenjen zagotavljanju praktičnih nasvetov o njegovi uporabi.
English: In over half of these patients other treatments for psoriasis had failed or the patients could not receive them.
Slovenian: Pri več kot polovici teh bolnikov druga zdravila za zdravljenje psoriaze niso bila uspešna oziroma jih niso mogli prejemati.
English: These cytokines are involved in inflammation and other processes that are important in psoriasis, psoriatic arthritis and Crohn's disease.
Slovenian: Ta citokina sta udeležena v vnetnih in drugih procesih, ki so pomembni pri psoriazi, psoriatičnem artritisu in Crohnovi bolezni.
English: • moderate to severe plaque psoriasis (a disease causing red, scaly patches on the skin).
Slovenian: • zmerne do hude psoriaze s plaki (bolezni, ki povzroča rdeče, luskaste zaplate na koži).
English: The most common side effects with Stelara (seen in more than 5% of patients during clinical trials) are headache and nasopharyngitis (inflammation of the nose and throat).
Slovenian: Najpogostejši neželeni učinki zdravila Stelara (opaženi med kliničnimi preskušanji pri več kot 5 % bolnikov) so glavobol in nazofaringitis (vnetje nosu in žrela).
English: For the full list of restrictions please see the package leaflet.
Slovenian: Za celoten seznam omejitev glejte navodilo za uporabo.
English: It is used in adults and children above the age of 12 years whose condition has not responded to or who cannot use other systemic (whole-body) psoriasis treatments, such as ciclosporin, methotrexate or PUVA (psoralen ultraviolet A).
Slovenian: Uporablja se pri odraslih in otrocih, starejših od 12 let, katerih bolezen se ni odzvala na drugo sistemsko zdravljenje psoriaze (zdravljenje, ki deluje na celotno telo), kot je zdravljenje s ciklosporinom, metotreksatom ali PUVA (psoralen in obsevanje z ultravijolično svetlobo A), ali ki tovrstnega zdravljenja ne morejo prejemati.
English: The most serious side effect reported with Stelara is serious hypersensitivity (allergic reaction).
Slovenian: Najresnejši neželeni učinek, opažen pri uporabi zdravila Stelara, je huda preobčutljivost (alergijska reakcija).
English: For adults the usual dose is 45 mg, whereas the dose in children depends on bodyweight.
Slovenian: Običajni odmerek za odrasle je 45 mg, odmerek za otroke pa je odvisen od njihove telesne mase.
English: An additional study involved 110 children with moderate to severe plaque psoriasis aged between 12 and 18 years.
Slovenian: V dodatno študijo je bilo vključenih 110 otrok, starih od 12 do 18 let, z zmerno do hudo psoriazo s plaki.
English: Some of the patients from the two main studies went on to receive Stelara (injection under the skin) every 8 or 12 weeks, or placebo.
Slovenian: Nekateri bolniki iz teh dveh študij so nadaljevali s prejemanjem bodisi zdravila Stelara (v obliki injekcij v podkožje) vsakih 8 ali 12 tednov bodisi placeba.
English: For more information about treatment with Stelara, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Stelara preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: In the second study the figures were 56% for Stelara and 29% for placebo.
Slovenian: V drugi študiji so rezultati znašali 56 % za zdravilo Stelara in 29 % za placebo.
English: In Crohn's disease, treatment is started with Stelara concentrate.
Slovenian: Pri Crohnovi bolezni se zdravljenje začne z zdravilom Stelara v obliki koncentrata.
English: PUVA is a type of treatment where the patient receives a medicine containing a compound called a ‘psoralen' before being exposed to ultraviolet light.
Slovenian: PUVA je vrsta terapije, pri kateri bolniku dajo zdravilo, ki vsebuje učinkovino psoralen, nato pa ga izpostavijo ultravijolični svetlobi.
English: Stelara may be used alone or combined with methotrexate (a DMARD);
Slovenian: Zdravilo Stelara se lahko uporablja kot samostojno zdravilo ali v kombinaciji z metotreksatom (ki spada med zdravila DMARD);
English: Stelara can only be obtained with a prescription and should be given under the supervision of a doctor who has experience in diagnosing and treating the diseases that Stelara is used for.
Slovenian: Predpisovanje in izdaja zdravila Stelara je le na recept, zdravljenje z njim pa se lahko uvede le pod nadzorom zdravnika, ki ima izkušnje z diagnosticiranjem in zdravljenjem bolezni, za katere se zdravilo Stelara uporablja.
English: Patients weighing over 100 kg should be given Stelara in 90-mg doses for psoriasis, and this should also be considered for psoriatic arthritis.
Slovenian: Bolnikom, ki tehtajo več kot 100 kg, se zdravilo Stelara pri psoriazi daje v 90-miligramskih odmerkih, o takšnem odmerku pa je treba razmisliti tudi pri bolnikih s psoriatičnim artritisom.
English: Eight weeks after the first infusion patients should receive 90 mg Stelara by injection under the skin.
Slovenian: Osem tednov po prvem infundiranju morajo bolniki prejeti 90 mg zdravila Stelara v obliki injekcije v podkožje.
English: Stelara was more effective than placebo at improving the symptoms of plaque psoriasis.
Slovenian: Zdravilo Stelara je bilo pri izboljšanju simptomov psoriaze s plaki učinkovitejše od placeba.