FrancophonIA/ELRC3.0 huggingface dataset:
English: Adjunctive therapy in the treatment of partial seizures, with or without secondary generalisation, in adolescent and paediatric patients (aged 6 years and above)
Estonian: Lisaravi noorukitel ja lastel (6-aastased ja vanemad) partsiaalsete epilepsiahoogude korral sekundaarse generaliseerumisega või ilma
English: • adjunctive therapy in the treatment of partial seizures, with or without secondary generalisation, in adults, adolescents, and children aged 6 years and above.
Estonian: • adjuvantravina täiskasvanutele, noorukitele, ning lastele vanuses 6 aastat ja vanemad, kellel esinevad partsiaalsed epilepsiahood sekundaarse generaliseerumisega või ilma.
English: • Other medicines like phenytoin, carbamazepine, phenobarbitone and rifampicin can decrease your blood levels of Zonegran, which may require an adjustment of your dose of Zonegran.
Estonian: • teised ravimid, nt fenütoiin, karbamasepiin, fenobarbitoon ja rifampitsiin, võivad vähendada
English: Serious immune based adverse reactions that are associated with medicinal products containing a sulphonamide group include rash, allergic reaction and major haematological disturbances, including aplastic anaemia, which very rarely can be fatal.
Estonian: Sulfoonamiidrühma sisaldavate ravimpreparaatidega seostatakse muu hulgas järgmisi raskeid immuunsusel põhinevaid kõrvaltoimeid: lööve, allergiline reaktsioon ja olulised hematoloogilised häired nagu aplastiline aneemia, mis väga harva võib lõppeda surmaga.
English: Zonegran 100 mg hard capsules contain 100 mg zonisamide.
Estonian: Zonegran 100 mg kõvakapslid sisaldavad 100 mg zonisamiidi.
English: • slowed thoughts, loss of concentration, speech abnormalities, abnormal skin sensation (pins and needles), tremor, involuntary movement of the eyes.
Estonian: • mõtete aeglustumine, kontsentratsiooni kadumine, kõnehäired, ebatavalised aistingud nahas
English: • The starting dose is 100 mg taken once a day.
Estonian: • algannus on 100 mg üks kord ööpäevas;
English: • Give your child plenty of cold water to drink
Estonian: • peab teie laps jooma palju külma vett
English: - Enzyme induction: Exposure to zonisamide is lower in epileptic patients receiving CYP3A4-inducing agents such as phenytoin, carbamazepine, and phenobarbitone.
Estonian: Epilepsiahaigetel, kes saavad CYP3A4 indutseerivaid ravimeid nagu fenütoiin, karbamasepiin ja fenobarbitoon, on zonisamiidi mõju väiksem.
English: Zonegran 100 mg hard capsules zonisamide
Estonian: Zonegran 100 mg kõvakapslid zonisamiid
English: • hallucinations, memory loss, coma, neuroleptic malignant syndrome (inability to move, sweating,
Estonian: • hallutsinatsioonid, mälukaotus, kooma, pahaloomuline neuroleptiline sündroom (liikumisvõimetus, higistamine, palavik, pidamatus), status epilepticus (pikaajalised või korduvad krambihood)
English: Zonegran 25 mg hard capsules contain 25 mg of zonisamide.
Estonian: Zonegran 25 mg kõvakapslid sisaldavad 25 mg zonisamiidi.
English: • lung infection / inflammation, urinary tract infections.
Estonian: • kopsuinfektsioon või kopsupõletik, kuseteede infektsioonid
English: Zonegran 50 mg hard capsules contain 50 mg zonisamide.
Estonian: Zonegran 50 mg kõvakapslid sisaldavad 50 mg zonisamiidi.
English: Zonegran 25 mg hard capsules zonisamide
Estonian: Zonegran 25 mg kõvakapslid zonisamiid
English: 300 - 500 mg/day (once a day)
Estonian: 300...500 mg ööpäevas (üks kord ööpäevas)
English: A syndrome consisting of acute myopia associated with secondary angle closure glaucoma has been reported in adult and paediatric patients receiving zonisamide.
Estonian: Zonisamiidi kasutavatel täiskasvanud ja lapspatsientidel on esinenud sekundaarse kinnise nurga glaukoomiga kaasneva ägeda müoopiana väljenduvat sündroomi.
English: A MANUFACTURER RESPONSIBLE FOR BATCH RELEASE
Estonian: RAVIMIPARTII KASUTAMISEKS VABASTAMISE EEST VASTUTAV TOOTJA
English: Titanium dioxide (E171) Allura red AC (E129) Sunset yellow FCF (E110) Shellac
Estonian: Kapsli kest želatiin titaandioksiid (E171) alluurpunane AC (E129) päikeseloojangukollane FCF (E110) šellak propüleenglükool kaaliumhüdroksiid must raudoksiid (E172)
English: Reduce the risk of kidney stones by drinking sufficient water.
Estonian: Neerukivide tekkimise riski vältimiseks jooge piisavalt vett;
English: A white opaque body and a white opaque cap printed with a logo and “ZONEGRAN 25” in black.
Estonian: Valge läbipaistmatu kapslikeha ja valge läbipaistmatu kapslikaas, millele on trükitud mustaga logo ja „ZONEGRAN 25”.
English: Black iron oxide (E172)
Estonian: Kapsli kest želatiin titaandioksiid (E171) šellak propüleenglükool kaaliumhüdroksiid must raudoksiid (E172)
English: EU/1/04/307/006 28 capsules EU/1/04/307/004 56 capsules EU/1/04/307/011 84 capsules EU/1/04/307/007 98 capsules EU/1/04/307/008 196 capsules
Estonian: EU/1/04/307/006 28 kapslit EU/1/04/307/004 56 kapslit EU/1/04/307/011 84 kapslit EU/1/04/307/007 98 kapslit EU/1/04/307/008 196 kapslit
English: A white opaque body and a red opaque cap printed with a logo and “ZONEGRAN 100” in black.
Estonian: Valge läbipaistmatu kapslikeha ja punane läbipaistmatu kapslikaas, millele on trükitud mustaga logo ja „ZONEGRAN 100”.
English: Patients must not take this medicinal product if they are allergic to peanut or soya.
Estonian: Patsiendid, kes on maapähkli või soja suhtes allergilised, ei tohi seda ravimit võtta.
English: • The child should stay cool especially in hot weather
Estonian: • hoidke lapse keha jahedana, eriti kuuma ilmaga
English: Adverse reactions associated with Zonegran obtained from clinical studies and post-marketing surveillance are tabulated below.
Estonian: Allpool on loetletud Zonegran'iga kliinilistes uuringutes ja turuletulekujärgselt saadud seostatud kõrvaltoimed.
English: 300 mg per day (once a day).
Estonian: 300 mg ööpäevas (üks kord ööpäevas)
English: Zonegran 50 mg hard capsules zonisamide
Estonian: Zonegran 50 mg kõvakapslid zonisamiid
English: Uncommon side effects (may affect up to 1 in 100 people):
Estonian: Aeg-ajalt esinevad kõrvaltoimed (võivad esineda kuni 1 inimesel 100st)
English: • swelling of the feet and legs.
Estonian: • säärte ja jalalabade turse
English: Zonegran 25 mg, 50 mg, and 100 mg hard capsules zonisamide
Estonian: Zonegran 25 mg kõvakapslid Zonegran 50 mg kõvakapslid Zonegran 100 mg kõvakapslid Zonisamiid
English: • loss of weight, nausea, indigestion, stomach pains, diarrhoea (loose stools), constipation.
Estonian: • kehakaalu alanemine, iiveldus, seedimatus, kõhuvalud, kõhulahtisus, kõhukinnisus
English: EU/1/04/307/010 14 capsules EU/1/04/307/009 28 capsules EU/1/04/307/003 56 capsules EU/1/04/307/012 84 capsules
Estonian: EU/1/04/307/010 14 kapslit EU/1/04/307/009 28 kapslit EU/1/04/307/003 56 kapslit EU/1/04/307/012 84 kapslit
English: Zonegran.
Estonian: Kõvakapsel.
English: A white opaque body and a grey opaque cap printed with a logo and “ZONEGRAN 50” in black.
Estonian: Valge läbipaistmatu kapslikeha ja hall läbipaistmatu kapslikaas, millele on trükitud mustaga logo ja „ZONEGRAN 50”.
English: Blood creatine phosphokinase increased Blood creatinine increased Blood urea increased Liver function tests abnormal
Estonian: Vere uureataseme tõus Maksafunktsiooni analüüside ebanormaalsus
English: Be especially careful while driving or operating machinery, if Zonegran affects you in this way.
Estonian: Kui Zonegran avaldab teile sellist mõju, peate olema autojuhtimisel ja masinatega töötamisel eriti ettevaatlik.
English: EU/1/04/307/001 14 capsules EU/1/04/307/005 28 capsules EU/1/04/307/002 56 capsules EU/1/04/307/013 84 capsules
Estonian: EU/1/04/307/001 14 kapslit EU/1/04/307/005 28 kapslit EU/1/04/307/002 56 kapslit EU/1/04/307/013 84 kapslit
English: Metabolic acidosis
Estonian: Leukopeenia Trombotsütopeenia
English: 200 mg /day (once a day)
Estonian: 200 mg ööpäevas (üks kord ööpäevas)
English: • With other antiepileptic medicines to treat seizures in adults, adolescents, and children aged
Estonian: • täiskasvanutel, noorukitel ja lastel vanuses 6 aastat ja vanemad epilepsiahoogude ravimiseks koos teiste epilepsiaravimitega.
English: • On its own to treat seizures in adults.
Estonian: • täiskasvanutel epilepsiahoogude ravimiseks ainsa ravimina;
English: Hypersensitivity-type Pneumonitis
Estonian: Sekundaarsed tooniliskloonilised
English: Common side effects (may affect up to 1 in 10 people):
Estonian: Sagedad kõrvaltoimed (võivad esineda kuni 1 inimesel 10st)
English: Adults - recommended dosage escalation and maintenance regimen
Estonian: Tabel 1 Täiskasvanud - annuse eskaleerimise ja säilitava ravi soovitatav raviskeem Raviskeem
English: Zonegran must not be used during pregnancy unless clearly necessary and only if the potential benefit is considered to justify the risk to the foetus.
Estonian: Seda võib kasutada vaid sel juhul, kui võimalikku kasu peetakse põhjendatuks, arvestades lootel avalduvat riski.
English: Take the child to a cool, shaded place Keep the child's skin cool with water Give the child cold water to drink
Estonian: • hoidke lapse nahk veega jahedana
English: Specialist medical advice should be given to women treated with zonisamide who are of childbearing potential.
Estonian: Zonisamiidiga ravitavad fertiilses eas naised peavad konsulteerima eriarstiga.
English: Capsule shells Gelatin
Estonian: Zonisamiid Karbamasepiin
English: Zonegran is indicated as:
Estonian: Zonegran on näidustatud
English: Zonegran 100 mg hard capsules
Estonian: Zonegran 100 mg kõvakapslid
English: If you are a woman of childbearing age you must use adequate contraception while taking and for one month after stopping Zonegran.
Estonian: Fertiilses eas naised peavad ravi ajal ja ühe kuu jooksul pärast ravi lõpetamist Zonegran'iga kasutama tõhusaid rasestumisvastaseid vahendeid.
English: Abdominal pain
Estonian: Metaboolne atsidoos
English: Hard capsule.
Estonian: - Ensüümide indutseerimine.
English: Hepatocellular damage
Estonian: Hepatotsellulaarne kahjustus
English: Zonegran 25 mg hard capsules
Estonian: Zonegran 25 mg kõvakapslid
English: • decreased sweating, overheating.
Estonian: • higistamise vähenemine, kuumarabandus
English: Cholecystitis Cholelithiasis
Estonian: 12 kuud krambihoogudeta
English: Zonegran 50 mg hard capsules
Estonian: Zonegran 50 mg kõvakapslid
English: Edurant rilpivirine
Estonian: Edurant rilpiviriin
English: A risk management plan has been developed to ensure that Edurant is used as safely as possible.
Estonian: Töötati välja riskijuhtimiskava, et tagada Eduranti võimalikult ohutu kasutamine.
English: The full EPAR for Edurant can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Estonian: Euroopa avaliku hindamisaruande täistekst Eduranti kohta on ameti veebilehel: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Edurant on 28 November 2011.
Estonian: Euroopa Komisjon andis Eduranti müügiloa, mis kehtib kogu Euroopa Liidu territooriumil, 28. novembril
English: What measures are being taken to ensure the safe and effective use of Edurant?
Estonian: Mis meetmed võetakse, et tagada Eduranti ohutu ja efektiivne kasutamine?
English: It is available as tablets (25 mg).
Estonian: Seda turustatakse 25 mg tablettidena.
English: Edurant must be taken with a meal.
Estonian: Eduranti peab võtma koos toiduga.
English: Other information about Edurant
Estonian: Muu teave Eduranti kohta
English: Edurant does not cure HIV infection or AIDS, but it may delay the damage to the immune system and the development of infections and diseases associated with AIDS.
Estonian: Edurant ei ravi HIV-nakkust ega AIDS-i välja, kuid võib immuunsüsteemi kahjustumist ning AIDS-iga seotud nakkuste ja haiguste tekkimist edasi lükata.
English: Edurant was also effective in adolescents, with around 72% of patients responding to treatment after 48 weeks.
Estonian: Edurant oli efektiivne ka noorukitel: ligikaudu 72%-l patsientidest tekkis 48 nädala järel ravivastus.
English: Edurant must not be used with the following medicines as they may lead to reduced blood levels of rilpivirine, and thereby reduce the effectiveness of Edurant:
Estonian: Eduranti ei tohi kasutada koos järgmiste ravimitega, sest need võivad vähendada vere rilpiviriinisisaldust ja seega Eduranti efektiivsust:
English: For more information about treatment with Edurant, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Estonian: Kui vajate Edurantiga toimuva ravi kohta lisateavet, lugege palun pakendi infolehte (mis on samuti Euroopa avaliku hindamisaruande osa) või pöörduge oma arsti või apteekri poole.
English: The recommended dose of Edurant is one tablet once a day.
Estonian: Eduranti soovitatav annus on üks tablett üks kord ööpäevas.
English: If Edurant is given together with rifabutin, the doctor should increase the dose of Edurant to two tablets once a day during rifabutin treatment.
Estonian: Kui Eduranti võetakse koos rifabutiiniga, peab arst suurendama Eduranti annust rifabutiini võtmise ajaks kahe tabletini ööpäevas.
English: The Committee noted that Edurant causes fewer side effects in the early stages of treatment and offers the benefit of being taken as one tablet once per day.
Estonian: Komitee märkis, et Edurant põhjustab varajastes ravietappides vähem kõrvalnähte ja selle eelis on manustamine ühe tabletina üks kord ööpäevas.
English: What is the risk associated with Edurant?
Estonian: Mis riskid Edurantiga kaasnevad?
English: Why has Edurant been approved?
Estonian: Miks Edurant heaks kiideti?
English: Edurant is a medicine that contains the active substance rilpivirine.
Estonian: Edurant on ravim, mis sisaldab toimeainena rilpiviriini.
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Edurant, including the appropriate precautions to be followed by healthcare professionals and patients.
Estonian: Selle alusel lisati Eduranti omaduste kokkuvõttesse ja pakendi infolehele ravimi ohutusteave, kus on ka tervishoiuspetsialistide ja patsientide võetavad meetmed.
English: This is a summary of the European public assessment report (EPAR) for Edurant.
Estonian: See on ravimi Edurant Euroopa avaliku hindamisaruande kokkuvõte.
English: The most frequent side effects with Edurant (seen in more than 1 patient in 10) are headache, insomnia, dizziness, nausea (feeling sick), and increased levels of total cholesterol, low-densitylipoprotein (LDL) cholesterol, pancreatic amylase (an enzyme produced in the pancreas that breaks down starch into sugars) and transaminases (liver enzymes).
Estonian: Eduranti kõige sagedamad kõrvalnähud (esinenud enam kui 1 patsiendil 10st) on peavalu, unetus, peapööritus, iiveldus ning üldkolesterooli, LDL-kolesterooli, pankrease amülaasi (pankreaseensüüm, mis lagundab tärklise suhkruteks) ja transaminaaside (maksaensüümide) suurenenud sisaldus veres.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Edurant.
Estonian: Selles selgitatakse, kuidas inimravimite komitee hindas ravimit ja otsustas toetada müügiloa andmist; samuti esitatakse komitee soovitused, kuidas ravimit kasutada.
English: Treatment with Edurant should be started by a doctor experienced in treating HIV infection.
Estonian: Ravi Edurantiga tohib alustada üksnes HIV-nakkuse ravis kogenud arst.
English: It is only used in patients who have not received anti-HIV treatment before and who have HIV levels in the blood (viral load) of no more than 100,000 HIV-1 RNA copies/ml.
Estonian: Eduranti kasutatakse ainult patsientidel, kes ei ole varem HIV-ravimeid saanud ja kelle vere HIV-sisaldus (viiruskoormus) ei ole suurem kui 100 000 HIV-1 RNA koopiat/ml.
English: In all studies, the main measure of effectiveness was based on the reduction in viral load.
Estonian: Kõigis uuringutes oli efektiivsuse põhinäitaja vere viiruskoormuse vähenemine.
English: Taking the two studies into account, 84% of patients taking Edurant responded to treatment after one year, compared with 82% of patients taking efavirenz.
Estonian: Kahes uuringus kokku oli patsiente, kellel tekkis aasta jooksul ravivastus, Eduranti rühmas 84% ja efavirensi rühmas 82%.
English: What is Edurant?
Estonian: Mis on Edurant?
English: By blocking this enzyme, Edurant, taken in combination with other antiviral medicines, reduces the amount of HIV in the blood and keeps it at a low level.
Estonian: Blokeerides selle ensüümi, vähendab koos teiste viiruseravimitega manustatav Edurant HIV-i kogust veres ja hoiab selle sisalduse väikese.
English: The CHMP concluded that Edurant, in combination with other antiretroviral medicines, was as effective as the main NNRTI currently used in the first-line treatment of adult patients infected with HIV-1.In addition, Edurant has also been shown to be effective in children aged 12 to 18 years of age.
Estonian: Inimravimite komitee järeldas, et Edurant koos teiste retroviiruseravimitega on sama efektiivne kui peamine NNRTI-ravim, mida praegu kasutatakse HIV-1 nakkusega täiskasvanud patsientide esmavaliku ravis.Edurant oli efektiivne ka 12-18-aastastel noorukitel.
English: Edurant was investigated in two main studies in 1,368 previously untreated adult patients infected with HIV-1.
Estonian: Eduranti uuriti kahes põhiuuringus 1368 varem ravimata täiskasvanud patsiendil, kellel oli HIV-1 nakkus.
English: Edurant is an antiviral medicine.
Estonian: Edurant on viiruseravim.
English: For the full list of all side effects reported with Edurant, see the package leaflet.
Estonian: Eduranti kohta teatatud kõrvalnähtude täielik loetelu on pakendi infolehel.
English: Therefore, the CHMP considered that the benefits of Edurant outweigh its risks in patients with a low HIV-1 viral load, and recommended that it be granted marketing authorisation for this group of patients.
Estonian: Seetõttu otsustas inimravimite komitee, et väikese HIV-1 viiruskoormusega patsientidel on Eduranti kasulikkus suurem kui sellega kaasnevad riskid, ja soovitas anda selle patsiendirühma jaoks ravimi müügiloa.
English: In the second study, Edurant was compared with efavirenz, when both medicines were given in combination with a fixed regimen of antiviral medicines consisting of tenofovir disoproxil and emtricitabine or two other nucleoside or nucleotide reverse transcriptase inhibitors.
Estonian: Teises uuringus võrreldi Eduranti efavirensiga, kusjuures mõlemat ravimit anti fikseeritud raviskeemis koos viiruseravimite tenofoviirdisoproksiili ja emtritsitabiiniga või fikseeritud raviskeemis koos kahe teise nukleosiidse või nukleotiidse pöördtranskriptaasi inhibiitoriga.
English: What benefit has Edurant shown during the studies?
Estonian: Milles seisneb uuringute põhjal Eduranti kasulikkus?
English: • carbamazepine, oxcarbazepine, phenobarbital, phenytoin (medicines for fits);
Estonian: • karbamasepiin, okskarbatsepiin, fenobarbitaal, fenütoiin (epilepsiaravimid);
English: Edurant was given in combination with a fixed regimen of antiviral medicines and was not compared with another treatment.
Estonian: Eduranti anti fikseeritud raviskeemis koos viiruseravimitega, kuid seda ei võrreldud muu raviga.
English: The active substance in Edurant, rilpivirine, is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Estonian: Eduranti toimeaine rilpiviriin on mittenukleosiidne pöördtranskriptaasi inhibiitor (NNRTI), mis blokeerib ensüümi pöördtranskriptaasi toime.
English: Edurant is used in combination with other antiviral medicines to treat adults and adolescents from the age of 12 years who are infected with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Estonian: Eduranti kasutatakse koos teiste viiruseravimitega, et ravida täiskasvanuid ja vähemalt 12-aastaseid noorukeid, kellel on inimese 1. tüüpi immuunpuudulikkuse viiruse (HIV-1) nakkus.
English: It blocks the activity of reverse transcriptase, an enzyme produced by HIV-1 that allows it to make more viruses in the cells it has infected.
Estonian: See HIV-1 tekitatav ensüüm võimaldab viirusel nakatunud rakkudes paljuneda.
English: Edurant was also investigated in another study in 36 previously untreated adolescents (between 12 and 18 years old) infected with HIV-1.
Estonian: Peale selle uuriti Eduranti veel ühes uuringus 36 varem ravimata 12-18-aastasel noorukil, kellel oli HIV-1 nakkus.
English: In the first study, Edurant was compared with another NNRTI called efavirenz, when both medicines were given in combination with a fixed regimen of antiviral medicines consisting of tenofovir disoproxil and emtricitabine.
Estonian: Esimeses uuringus võrreldi Eduranti teise NNRTI-ravimi efavirensiga, kusjuures mõlemaid ravimeid anti fikseeritud raviskeemis koos viiruseravimite tenofoviirdisoproksiili ja emtritsitabiiniga.
English: How is Edurant used?
Estonian: Kuidas Eduranti kasutatakse?
English: In adults, Edurant in combination with other antiretroviral medicines was as effective as the comparator medicine at reducing the level of HIV-1 in the patients' blood.
Estonian: Täiskasvanutel vähendas Edurant koos teiste retroviiruseravimitega vere HIV-1 sisaldust sama efektiivselt kui võrdlusravim.
English: What is Edurant used for?
Estonian: Milleks Eduranti kasutatakse?
English: • St John's wort (a herbal antidepressant medicine).
Estonian: • naistepuna (taimne antidepressant).
English: How has Edurant been studied?
Estonian: Kuidas Eduranti uuriti?
English: How does Edurant work?
Estonian: Kuidas Edurant toimib?
English: Caution is needed in these patients.
Estonian: Selliste patsientide puhul on nõutav ettevaatus.
English: The diluted solution must be clear and colourless.
Estonian: Lahjendatud lahus peab olema selge ja värvitu.
English: Date of first authorisation: 05 March 2002 Date of latest renewal: 05 March 2007
Estonian: Müügiloa esmase väljastamise kuupäev: 05. märts 2002 Müügiloa viimase uuendamise kuupäev: 05. märts 2007
English: - In addition, you will receive electrocardiograms twice weekly.
Estonian: - Lisaks sellele tehakse teile kaks korda nädalas elektrokardiogramm.
English: This accumulation was slightly more than expected based on single-dose results.
Estonian: See akumulatsioon oli veidi suurem, kui oli eeldatud ühekordse annusega saadud tulemuste põhjal.
English: This means that the medicine is essentially ‘sodium-free'.
Estonian: See tähendab, et ravim on põhimõtteliselt „naatriumivaba“.
English: NEW CONCENTRATION
Estonian: UUS KONTSENTRATSIOON
English: Confidence interval (CI)
Estonian: Usaldusvahemik (CI)
English: If you are not sure, show the bottle or pack to your doctor.
Estonian: Kui te ei ole milleski kindel, näidake pudelit või pakendit oma arstile.
English: Negative Positive Not evaluable
Estonian: Negatiivne Positiivne Ei ole määratav
English: You must be sure to tell your doctor about all medicines you are taking.
Estonian: Rääkige kindlasti arstile kõigist ravimitest, mida võtate.
English: Currently available data for children aged 5 to 16 years are described in section 5.1 but no recommendation on a posology can be made.
Estonian: Antud hetkel teadaolevad andmed laste kohta vanuses 5…16 aastat on esitatud lõigus 5.1, aga soovitusi annustamise kohta ei ole võimalik anda.
English: The response rate was similar for both genders.
Estonian: Ravivastuse esinemissagedus oli mõlema soo puhul sarnane.
English: Vd is also weight dependent, increasing with increasing body weight.
Estonian: Vd sõltub ka kehakaalust, suurenedes kehakaalu kasvades.
English: AsV is present in plasma only at relatively low levels.
Estonian: AsV sisaldus plasmas on siiski suhteliselt madal.
English: A central venous catheter is not required.
Estonian: Tsentraalne veenikateeter ei ole vajalik.
English: The safety and efficacy of TRISENOX in children aged up to 17 years has not been established.
Estonian: TRISENOX'i ohutus ja efektiivsus lastel vanuses kuni 17 aastat ei ole tõestatud.
English: The extent of accumulation of these metabolites is dependent on the dosing regimen.
Estonian: Nende metaboliitide akumulatsiooni ulatus sõltub annustamisskeemist.