FrancophonIA/ELRC3.0 huggingface dataset:
English: Vizarsin orodispersible tablets are available in boxes of 1 orodispersible tablet in blisters and also in boxes of 2 x 1, 4 x 1, 8 x 1, 12 x 1 or 24 x 1 orodispersible tablet in a perforated unit dose blisters.
Croatian: Vizarsin raspadljive tablete za usta su dostupne u kutijama s 1 raspadljivom tabletom za usta u blisterima te također u kutijama od 2 x 1, 4 x 1, 8 x 1, 12 x 1 ili 24 x 1 raspadljivih tableta za usta u blisterima s perforiranim jediničnim dozama.
English: Vizarsin 25 mg orodispersible tablets
Croatian: Vizarsin 25 mg raspadljive tablete za usta
English: Each film-coated tablet contains sildenafil citrate equivalent to 25 mg sildenafil.
Croatian: Jedna filmom obložena tableta sadrži sildenafilcitrat koji odgovara 25 mg sildenafila.
English: 4 x 1 film-coated tablet: EU/1/09/551/010 8 x 1 film-coated tablet: EU/1/09/551/011 12 x 1 film-coated tablet: EU/1/09/551/012
Croatian: 4 x 1 filmom obložena tableta: EU/1/09/551/010 8 x 1 filmom obložena tableta: EU/1/09/551/011 12 x 1 filmom obložena tableta: EU/1/09/551/012
English: Uncommon ( 1/1000 and
Croatian: Rijetko ( 1/10000 do <1/1000)
English: Vizarsin 100 mg orodispersible tablets
Croatian: Vizarsin 100 mg raspadljive tablete za usta
English: Vizarsin 50 mg film-coated tablets Sildenafil
Croatian: Vizarsin 50 mg filmom obložene tablete sildenafil
English: Vizarsin 100 mg film-coated tablets Sildenafil
Croatian: Vizarsin 100 mg filmom obložene tablete sildenafil
English: 4 x 1 film-coated tablet: EU/1/09/551/006 8 x 1 film-coated tablet: EU/1/09/551/007 12 x 1 film-coated tablet: EU/1/09/551/008
Croatian: 4 x 1 filmom obložena tableta: EU/1/09/551/006 8 x 1 filmom obložena tableta: EU/1/09/551/007 12 x 1 filmom obložena tableta: EU/1/09/551/008
English: 1 film-coated tablet: EU/1/09/551/001
Croatian: 1 filmom obložena tableta: EU/1/09/551/001
English: KRKA Pharma Dublin, Ltd. Tel: + 353 1 293 91 80
Croatian: KERN PHARMA, S.L. Tel: + 34 93 700 25 25
English: I!
Croatian: E.
English: Vizarsin 25 mg orodispersible tablets Sildenafil
Croatian: Vizarsin 25 mg raspadljive tablete za usta sildenafil
English: Each film-coated tablet contains sildenafil citrate equivalent to 50 mg sildenafil.
Croatian: Jedna filmom obložena tableta sadrži sildenafilcitrat koji odgovara 50 mg sildenafila.
English: fl\\
Croatian: \/ çJ
English: 1 film-coated tablet: EU/1/09/551/009
Croatian: 1 filmom obložena tableta: EU/1/09/551/009
English: 1 film-coated tablet: EU/1/09/551/005
Croatian: 1 filmom obložena tableta: EU/1/09/551/005
English: Vizarsin orodispersible tablets are available in boxes of 1 orodispersible tablet in blisters and also in boxes of 2 x 1, 4 x 1, 8 x 1 or 12 x 1 orodispersible tablet in a perforated unit dose blisters.
Croatian: Vizarsin raspadljive tablete za usta su dostupne u kutijama s 1 raspadljivom tabletom za usta u blisterima te također u kutijama od 2 x 1, 4 x 1, 8 x 1 ili 12 x 1 raspadljivih tableta za usta u blisterima s perforiranim jediničnim dozama.
English: 4 x 1 film-coated tablet: EU/1/09/551/002 8 x 1 film-coated tablet: EU/1/09/551/003 12 x 1 film-coated tablet: EU/1/09/551/004
Croatian: 4 x 1 filmom obložena tableta: EU/1/09/551/002 8 x 1 filmom obložena tableta: EU/1/09/551/003 12 x 1 filmom obložena tableta: EU/1/09/551/004
English: Vizarsin 25 mg film-coated tablets are available in boxes of 1 film-coated tablet in blisters and also in boxes of 4 x 1, 8 x 1 or 12 x 1 film-coated tablet in a perforated unit dose blisters.
Croatian: Vizarsin 25 mg filmom obložene tablete dostupne su u kutijama s 1 filmom obloženom tabletom u blisterima te također u kutijama s 4 x 1, 8 x 1 ili 12 x 1 filmom obloženih tableta u perforiranim blisterima djeljivim na jedinične doze.
English: Retinal vascular occlusion
Croatian: Prijavljivanje nuspojava
English: Vizarsin 100 mg film-coated tablets are available in boxes of 1 film-coated tablet in blisters and also in boxes of 4 x 1, 8 x 1 or 12 x 1 film-coated tablet in a perforated unit dose blisters.
Croatian: Vizarsin 100 mg filmom obložene tablete dostupne su u kutijama s 1 filmom obloženom tabletom u blisterima te također u kutijama s 4 x 1, 8 x 1 ili 12 x 1 filmom obloženih tableta u perforiranim blisterima djeljivim na jedinične doze.
English: Vizarsin 100 mg orodispersible tablets Sildenafil
Croatian: Vizarsin 100 mg raspadljive tablete za usta sildenafil
English: Vizarsin 50 mg orodispersible tablets
Croatian: Vizarsin 50 mg raspadljive tablete za usta
English: An allergic reaction - this occurs uncommonly (may affect up to 1 in 100 people) Symptoms include sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat.
Croatian: Simptomi uključuju iznenadno piskanje, otežano disanje ili omaglicu, oticanje očnih kapaka, lica, usana ili ždrijela.
English: Vizarsin 50 mg film-coated tablets are available in boxes of 1 film-coated tablet in blisters and also in boxes of 4 x 1, 8 x 1 or 12 x 1 film-coated tablet in a perforated unit dose blisters.
Croatian: Vizarsin 50 mg filmom obložene tablete dostupne su u kutijama s 1 filmom obloženom tabletom u blisterima te također u kutijama s 4 x 1, 8 x 1 ili 12 x 1 filmom obloženih tableta u perforiranim blisterima djeljivim na jedinične doze.
English: 2 x 1 orodispersible tablet: EU/1/09/551/024 4 x 1 orodispersible tablet: EU/1/09/551/025 8 x 1 orodispersible tablet: EU/1/09/551/026 12 x 1 orodispersible tablet: EU/1/09/551/027 24 x 1 orodispersible tablet: EU/1/09/551/029
Croatian: 2 x 1 raspadljiva tableta za usta: EU/1/09/551/024 4 x 1 raspadljiva tableta za usta: EU/1/09/551/025 8 x 1 raspadljiva tableta za usta: EU/1/09/551/026 12 x 1 raspadljiva tableta za usta: EU/1/09/551/027 24 x 1 raspadljiva tableta za usta: EU/1/09/551/029
English: Vizarsin 50 mg orodispersible tablets Sildenafil
Croatian: Vizarsin 50 mg raspadljive tablete za usta sildenafil
English: 1 orodispersible tablet: EU/1/09/551/013 2 x 1 orodispersible tablet: EU/1/09/551/014 4 x 1 orodispersible tablet: EU/1/09/551/015 8 x 1 orodispersible tablet: EU/1/09/551/016 12 x 1 orodispersible tablet: EU/1/09/551/017
Croatian: 1 raspadljiva tableta za usta: EU/1/09/551/013 2 x 1 raspadljiva tableta za usta: EU/1/09/551/014 4 x 1 raspadljiva tableta za usta: EU/1/09/551/015 8 x 1 raspadljiva tableta za usta: EU/1/09/551/016 12 x 1 raspadljiva tableta za usta: EU/1/09/551/017
English: 2 x 1 orodispersible tablet: EU/1/09/551/019 4 x 1 orodispersible tablet: EU/1/09/551/020 8 x 1 orodispersible tablet: EU/1/09/551/021 12 x 1 orodispersible tablet: EU/1/09/551/022 24 x 1 orodispersible tablet: EU/1/09/551/028
Croatian: 2 x 1 raspadljiva tableta za usta: EU/1/09/551/019 4 x 1 raspadljiva tableta za usta: EU/1/09/551/020 8 x 1 raspadljiva tableta za usta: EU/1/09/551/021 12 x 1 raspadljiva tableta za usta: EU/1/09/551/022 24 x 1 raspadljiva tableta za usta: EU/1/09/551/028
English: 2 x 1 orodispersible tablet: EU/1/09/551/014 4 x 1 orodispersible tablet: EU/1/09/551/015 8 x 1 orodispersible tablet: EU/1/09/551/016 12 x 1 orodispersible tablet: EU/1/09/551/017
Croatian: 2 x 1 raspadljiva tableta za usta: EU/1/09/551/014 4 x 1 raspadljiva tableta za usta: EU/1/09/551/015 8 x 1 raspadljiva tableta za usta: EU/1/09/551/016 12 x 1 raspadljiva tableta za usta: EU/1/09/551/017
English: Czech Republic TEVA Czech Industries s.r.o.
Croatian: Češka Republika TEVA Czech Industries s.r.o.
English: Annex I List of the names, pharmaceutical form(s), strength(s) of the medicinal product(s), route(s) of administration, marketing authorisation holder(s) in the member states
Croatian: Lista naziva, farmaceutskih oblika, jačine medicinskog (medicinskih) proizvoda, način(i) primjene, nositelj (i) marketing autorizacije u državama članicama
English: Capsule hard
Croatian: Kapsula, tvrda
English: ERGODAVUR GOTAS 1 mg (monodose suchet)
Croatian: ERGODAVUR GOTAS 1 mg (vrećica sa jednom dozom)
English: 2.5 mg (1:1:1) prolonged-release capsule, soft
Croatian: 2.5 mg (1:1:1) kapsule s produljenim oslobađanjem, meke
English: 0.10 g / 0.80 g oral solution
Croatian: 0.10 g / 0.80 g oralna otopina
English: powder for oral solution for single dose
Croatian: prašak za oralnu otopinu za jednu dozu
English: Ferraz 80, 5º 28008 Madrid Spain
Croatian: TORA LABORATORIES S.L. Ferraz 80, 5º 28008 Madrid Spain
English: PHARM O.E.
Croatian: S.J.A. PHARM O.E.
English: ISKEDYL, solution injectable en ampoule solution for injection IV/IM
Croatian: ISKEDYL, solution injectable en ampoule
English: ANTOR LTD P. MAVROMIHALI 1 VRILISSIA 15235 Greece
Croatian: MAVROMIHALI 1 VRILISSIA 15235 Greece
English: G. KORONIS DILOU 9, PERISTERI, ATTIKIS, 12134 Greece
Croatian: PHARMACEUTICAL INDUSTRY PROEL EPAM. G. KORONIS DILOU 9, PERISTERI, ATTIKIS, 12134
English: 6MG/SINGLE DOSE
Croatian: 6mg/PO JEDNOJ DOZI
English: VOCATE PHARMAKEFTIKI A.E.
Croatian: VOCATE PHARMAKEFTIKI
English: S.J.A.
Croatian: A.E.
English: 3mg/cap capsules, soft
Croatian: 3mg/kaps
English: This will help protect the pigs against the infection and reduce the risk of disease.
Croatian: To će pomoći u zaštiti svinja od infekcije i smanjiti rizik od bolesti.
English: This summary was last updated in November 2016.
Croatian: Sažetak je posljednji put ažuriran u 11-2016.
English: E. coli O8:K87 / O141:K94 vaccine (live)
Croatian: E. coli O8:K87 / O141:K94 cjepivo (živo)
English: The strains of bacteria in the vaccine have these proteins but do not produce the toxins that cause the disease.
Croatian: Sojevi bakterija u cjepivu sadrže ove proteine, no ne proizvode toksine koji uzrokuju bolest.
English: This is more likely to occur at weaning time when the piglet no longer receives protecting antibodies through the sow's milk.
Croatian: Vjerojatnost za to je veća tijekom razdoblja odbića, kad prasad više ne dobiva zaštitna protutijela iz mlijeka krmače.
English: The full EPAR for Coliprotec F4/F18 can be found on the Agency's website: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
Croatian: Cjeloviti EPAR za VMP Coliprotec F4/F18 nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
English: The effectiveness of the vaccine was studied in four laboratory studies in pigs that looked chiefly at the incidence, severity and duration of diarrhoea as well as the presence of disease-causing E. coli in the animals' excrement.
Croatian: Djelotvornost cjepiva ispitivana je u okviru četiriju laboratorijskih ispitivanja na svinjama u kojima se uglavnom promatrala incidencija, težina i trajanje proljeva, kao i prisutnost bakterije E. coli koja uzrokuje bolest u izmetu životinja.
English: Although E. coli bacteria are naturally found in the gut, some strains (known as enterotoxigenic strains) produce toxins that cause diarrhoea and can result in dehydration, weight loss and occasionally death of the animal.
Croatian: Iako su bakterije E. coli prirodno prisutne u crijevima, određeni sojevi (poznati pod nazivom enterotoksigeni sojevi) proizvode toksine koji uzrokuju proljev, a mogu rezultirati dehidracijom, smanjenjem tjelesne mase, a ponekad i smrću životinja.
English: In the future, if the animals are exposed to disease-causing bacteria with the F4 or F18 proteins, the immune system will be able to respond more quickly.
Croatian: Ako životinje ubuduće budu izložene bakteriji koja uzrokuje bolest i sadrži proteine F4 ili F18, imunosni sustav moći će brže reagirati.
English: Two studies showed the vaccine starts to be effective 7 days after vaccination and two studies showed protection lasts for 21 days after vaccination.
Croatian: Dva ispitivanja pokazala su da cjepivo postaje djelotvorno 7 dana nakon cijepljenja, a dva druga ispitivanja da zaštita traje do 21 dan nakon cijepljenja.
English: Coliprotec F4/F18 contains two strains of live E. coli bacteria (O8:K87 and O141:K94) which do not produce toxins that cause disease.
Croatian: VMP Coliprotec F4/F18 sadrži dva soja živih bakterija E. coli (O8:K87 i O141:K94) koje ne proizvode toksine koji izazivaju bolest.
English: The withdrawal period for meat from pigs treated with Coliprotec F4/F18 is ‘zero' days, which means there is no mandatory waiting time.
Croatian: Razdoblje karencije za meso svinja liječenih VMP-om Coliprotec F4/F18 iznosi „nula” dana, drugim riječima, nema obveznog perioda čekanja.
English: The types of E. coli associated with post-weaning diarrhoea often produce proteins called F4 and F18 on their outer coat that allows them to attach to the cells of the gut.
Croatian: Tipovi bakterije E. coli povezani s proljevom nakon odbića često proizvode proteine naziva F4 i F18 u vanjskoj ovojnici koja im omogućuje vezivanje na stanice u crijevima.
English: When Coliprotec F4/F18 is given to pigs, the animals' immune system recognises the bacteria as ‘foreign' and makes antibodies against them.
Croatian: Kada se Coliprotec F4/F18 daje svinjama, imunosni sustav životinje prepoznaje bakterije kao „strana tijela” i proizvodi protutijela.
English: The Agency's Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Coliprotec F4/F18's benefits are greater than its risks and recommended that it be approved for use in the EU.
Croatian: Odbor za veterinarsko-medicinske proizvode (CVMP) pri Agenciji odlučio je da koristi od VMP-a Coliprotec F4/F18 nadmašuju s njim povezane rizike te je preporučio njegovo odobrenje za primjenu u Europskoj uniji.
English: In case of spillage onto skin, the affected area should be rinsed with water and medical advice should be sought immediately and the package leaflet or label shown to the doctor.
Croatian: U slučaju da se prolije na kožu, zahvaćeno područje potrebno je smjesta isprati vodom i smjesta potražiti liječnički savjet te liječniku pokazati uputu o VMP-u ili naljepnicu.
English: Pigs aged 17 - 18 days were vaccinated with Coliprotec F4/F18 and then artificially infected with E. coli strains.
Croatian: Svinje stare 17 do 18 dana cijepljene su VMP-om Coliprotec F4/F18 i potom umjetno zaražene sojevima bakterije E. coli.
English: Two studies used the F4 strain while the other two used the F18 strain.
Croatian: U dvama ispitivanjima korišten je soj F4, a u drugim dvama ispitivanjima soj F18.
English: The European Commission granted a marketing authorisation valid throughout the EU for Coliprotec F4/F18 on 9 January 2017.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje je za VMP Coliprotec F4/F18 na snazi u Europskoj uniji od 09/01/2017.
English: The vaccine starts to be effective 7 days after vaccination and protection lasts for 21 days after vaccination.
Croatian: Cjepivo postaje djelotvorno 7 dana nakon cijepljenja, a zaštita traje do 21 dan nakon cijepljenja.
English: Coliprotec F4/F18 is available as a lyophilisate (a freeze-dried pellet) which is made up into a suspension with water to be given by mouth.
Croatian: VMP Coliprotec F4/F18 dostupan je kao liofilizat (smrzavanjem osušen pelet) koji se pripravlja s vodom radi pripreme suspenzije za primjenu kroz usta.
English: In case of accidental ingestion, medical advice should be sought immediately and the package leaflet or label shown to the doctor.
Croatian: U slučaju nehotičnog gutanja potrebno je smjesta potražiti liječnički savjet te liječniku pokazati uputu o VMP-u ili naljepnicu.
English: Personal protective equipment consisting of protective disposable gloves and safety glasses should be worn when handling the vaccine.
Croatian: Pri rukovanju s cjepivom potrebno je upotrebljavati pribor za osobnu zaštitu koji se sastoji od zaštitnih jednokratnih rukavica i sigurnosnih naočala.
English: Coliprotec F4/F18 is a vaccine used to protect pigs from 18 days of age against post-weaning diarrhoea caused by E. coli.
Croatian: VMP Coliprotec F4/F18 je cjepivo koje se primjenjuje za zaštitu svinja starijih od 18 dana od proljeva nakon odbića izazvanog bakterijom E. coli.
English: Coliprotec F4/F18 is given by mouth to pigs as a single dose either as a drench or by addition to the drinking water.
Croatian: VMP Coliprotec F4/F18 se u svinja primjenjuje kroz usta kao jedna doza nalijevanjem ili dodavanjem u vodu za piće.
English: This is a summary of the European public assessment report (EPAR) for Coliprotec F4/F18.
Croatian: Ovo je sažetak europskoga javnog izvješća o procjeni (EPAR) veterinarsko-medicinskog proizvoda Coliprotec F4/F18.
English: What is Coliprotec F4/F18 and what is it used for?
Croatian: Što je Coliprotec F4/F18 i za što se koristi?
English: For practical information about using Coliprotec F4/F18, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Praktične informacije o primjeni VMP-a Coliprotec F4/F18 vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svojem veterinaru ili ljekarniku.
English: For more information about treatment with Coliprotec F4/F18, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Dodatne informacije o terapiji VMP-om Coliprotec F4/F18 vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svojem veterinaru ili ljekarniku.
English: Coliprotec F4/F18 is a vaccine.
Croatian: Coliprotec F4/F18 je cjepivo.
English: There are currently no known side effects associated with Coliprotec F4/F18.
Croatian: Trenutačno nema poznatih nuspojava povezanih s VMP-om Coliprotec F4/F18.
English: It is not intended to provide practical advice on how to use Coliprotec F4/F18.
Croatian: Svrha sažetka nije davati praktične savjete o primjeni VMP-a Coliprotec F4/F18.
English: What are the risks associated with Coliprotec F4/F18?
Croatian: Koji su rizici povezani s VMP-om Coliprotec F4/F18?
English: Why is Coliprotec F4/F18 approved?
Croatian: Zašto je Coliprotec F4/F18 odobren?
English: The vaccine reduced the number of pigs with moderate to severe diarrhoea compared to non-vaccinated pigs.
Croatian: U usporedbi sa svinjama koje nisu cijepljene, u cijepljenih svinja smanjen je broj onih s umjerenim do teškim proljevom.
English: What benefits of Coliprotec F4/F18 have been shown in studies?
Croatian: Koje su koristi VMP-a Coliprotec F4/F18 dokazane u ispitivanjima?
English: How does Coliprotec F4/F18 work?
Croatian: Kako Coliprotec F4/F18 djeluje?
English: Other information about Coliprotec F4/F18?
Croatian: Ostale informacije o VMP-u Coliprotec F4/F18
English: How is Coliprotec F4/F18 used?
Croatian: Kako se koristi Coliprotec F4/F18?
English: The recommended dose is one tablet taken once a day with food for 8 or 12 weeks.
Croatian: Preporučena je doza jedna tableta jedanput na dan uz obrok tijekom 8 ili 12 tjedana.
English: Vosevi must not be used together with certain medicines such as:
Croatian: Lijek Vosevi ne smije se uzimati s određenim lijekovima kao što su:
English: The full EPAR for Vosevi can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Croatian: Cjeloviti EPAR za lijek Vosevi nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: Other information about Vosevi
Croatian: Ostale informacije o lijeku Vosevi
English: What is Vosevi and what is it used for?
Croatian: Što je Vosevi i za što se koristi?
English: What measures are being taken to ensure the safe and effective use of Vosevi?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Vosevi?
English: Sofosbuvir/velpatasvir has been authorised in the EU as Epclusa since July 2016.
Croatian: Sofosbuvir/velpatasvir odobren je u Europskoj uniji od srpnja 2016. pod nazivom Epclusa.
English: This is a summary of the European public assessment report (EPAR) for Vosevi.
Croatian: Ovo je sažetak europskoga javnog izvješća o procjeni (EPAR) lijeka Vosevi.
English: Vosevi sofosbuvir / velpatasvir / voxilaprevir
Croatian: Vosevi sofosbuvir/velpatasvir/voksilaprevir
English: The clearance rates with Vosevi were typically above 95%.
Croatian: Stope uklanjanja lijekom Vosevi uglavnom su bile iznad 95 %.
English: What are the risks associated with Vosevi?
Croatian: Koji su rizici povezani s lijekom Vosevi?
English: The most common side effects with Vosevi (which may affect more than 1 in 10 people) are headache, nausea (feeling sick) and diarrhoea.
Croatian: Najčešće nuspojave lijeka Vosevi (koje se mogu pojaviti u više od 1 na 10 osoba) jesu glavobolja, mučnina (osjećaj slabosti) i proljev.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Vosevi have also been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Vosevi nalaze se također u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: It is not intended to provide practical advice on how to use Vosevi.
Croatian: Svrha sažetka nije davati praktične savjete o primjeni lijeka Vosevi.
English: The European Medicines Agency therefore decided that Vosevi's benefits are greater than its risks and recommended that it be approved for use in the EU.
Croatian: Stoga je Europska agencija za lijekove zaključila da koristi lijeka Vosevi nadmašuju s njim povezane rizike te je preporučila njegovo odobrenje za primjenu u Europskoj uniji.
English: Sofosbuvir blocks the action of an enzyme (a type of protein) called ‘NS5B RNA-dependent RNA polymerase', velpatasvir targets a protein called ‘NS5A', while voxilaprevir blocks an enzyme called NS3/4A protease.
Croatian: Sofosbuvir inhibira djelovanje enzima (vrsta proteina) naziva „RNK-ovisna RNK polimeraza NS5B”, velpatasvir je usmjeren na protein naziva „NS5A”, dok voksilaprevir inhibira djelovanje enzima naziva „proteaza NS3/4A”.
English: • rifampicin, rifabutin (antibiotics usually used to treat tuberculosis);
Croatian: • rifampicin, rifabutin (antibiotici koji se obično koriste za liječenje tuberkuloze);
English: Vosevi is available as tablets containing 400 mg sofosbuvir, 100 mg velpatasvir and 100 mg voxilaprevir.
Croatian: Lijek Vosevi dostupan je u obliku tableta koje sadržavaju 400 mg sofosbuvira, 100 mg velpatasvira i 100 mg voksilaprevira.
English: Why is Vosevi approved?
Croatian: Zašto je lijek Vosevi odobren?
English: Over 96% of patients taking Vosevi in one study tested negative for HCV (their blood tests did not show any sign of the virus) after 12 weeks of treatment, compared with none of the patients who received placebo (a dummy treatment).
Croatian: Više od 96 % bolesnika koji su primili lijek Vosevi u jednom ispitivanju imali su negativne rezultate testiranja na HCV (njihove krvne pretrage nisu pokazivale nikakve znakove virusa) nakon 12 tjedana liječenja, u usporedbi s nijednim od bolesnika koji su primili placebo (prividno liječenje).
English: This study is being carried out in light of data suggesting that patients treated with medicines belonging to the same class as Vosevi who have had liver cancer could be at risk of their cancer returning early.
Croatian: To ispitivanje provodi se s obzirom na podatke koji upućuju na to da bi liječenje lijekovima koji pripadaju istom razredu kao lijek Vosevi moglo izložiti bolesnike koji su bolovali od raka jetre opasnosti od ranog povratka raka.
English: • rosuvastatin (medicine for lowering cholesterol in the blood);
Croatian: • rosuvastatin (lijek za smanjenje razine kolesterola u krvi);
English: The company that markets Vosevi will carry out a study in patients who previously have had liver cancer to evaluate the risk of liver cancer returning after treatment with direct-acting antivirals.
Croatian: Tvrtka koja stavlja na tržište lijek Vosevi provest će ispitivanje na bolesnicima koji su prethodno bolovali od raka jetre kako bi se procijenio rizik od povratka raka jetre nakon liječenja protuvirusnim lijekovima s izravnim djelovanjem.