FrancophonIA/ELRC3.0 huggingface dataset:
English: • The risk of bladder cancer risk and relevant risk minimisation advice.
Maltese: • Ir-riskju ta' riskju tal-kanċer tal-bużżieqa u parir rilevanti għat-tnaqqis tar-riskju.
English: 3 In controlled clinical trials the incidence of reports of heart failure with pioglitazone treatment was the same as in placebo, metformin and sulphonylurea treatment groups, but was increased when used in combination therapy with insulin.
Maltese: 3 Fi provi kliniċi kkontrollati, l-inċidenza ta' rapporti ta' insuffiċjenza tal-qalb b'kura b'pioglitazone kienet l-istess bħall-gruppi ta' kura bil-plaċebo, metformin u sulphonylurea, iżda żdiedet meta ntuża f'terapija kombinata ma' insulina.
English: Pioglitazone Teva 30 mg tablets
Maltese: Pioglitazone Teva 30 mg pilloli
English: The safety and efficacy of pioglitazone in children and adolescents under 18 years of age have not been established.
Maltese: Is-sigurtà u l-effikaċja ta' pioglitazone f'pazjenti taħt l-età ta' 18-il sena, ma ġewx stabiliti.
English: Adverse reactions reported in excess (> 0.5%) of placebo and as more than an isolated case in patients receiving pioglitazone in double-blind studies are listed below as MedDRA preferred term by system organ class and absolute frequency.
Maltese: Lista ta' reazzjonijiet avversi f'tabella Reazzjonijiet avversi rrappurtati aktar (> 0.5%) milli fil-plaċebo u f'aktar minn każ iżolat f'pazjenti li qed jirċievu pioglitazone fi studji double-blind huma mniżżla hawn taħt bis-sistema ta' terminu ppreferut MedDRA permeżż tas-sistema tal-klassifika tal-organi u frekwenza assoluta.
English: Pioglitazone or placebo was added to existing antidiabetic and cardiovascular therapy for up to 3.5 years.
Maltese: Pioglitazone jew plaċebo kienu miżjuda mat-terapija anti-dijabetika u kardjovaskulari eżistenti sa 3.5 snin.
English: Pioglitazone Teva 45 mg tablets
Maltese: Pioglitazone Teva 45 mg pilloli
English: Combination with metformin with sulphonylurea with metformin and sulphonylurea with insulin
Maltese: Taħlita ma' metformin ma' Sulphonylurea ma' metformin u sulphonylurea ma' insulina
English: Sun.
Maltese: Teva.
English: In clinical trials of up to two years duration, pioglitazone reduced total plasma triglycerides and free fatty acids, and increased HDL cholesterol levels, compared with placebo, metformin or gliclazide.
Maltese: Fi provi kliniċi li damu sa sentejn, pioglitazone naqqas it-triġliċeridi totali fil-plażma u l-fatty acids ħielsa, u żied l-livelli ta' HDL kolesterol, meta mqabbel mal-plaċebo, metformin jew gliclazide.
English: Blood and lymphatic system disorders anaemia common
Maltese: Disturbi tad-demm u tas-sistema limfatika anemija
English: Post-marketing reports of new-onset or worsening diabetic macular oedema with decreased visual acuity have been reported with thiazolidinediones, including pioglitazone.
Maltese: Rapporti ta' wara t-tqegħid fis-suq ta' żvilupp jew irkadar ta' edima makulari dijabetika bi tnaqqis flakutezza viżiva ġew irrappurtati b' thiazolidinediones, inkluż pioglitazone.
English: 4 A pooled analysis was conducted of adverse reactions of bone fractures from randomised, comparator controlled, double blind clinical trials in over 8100 patients in the pioglitazone-treated groups and 7400 in the comparator-treated groups of up to 3.5 years duration.
Maltese: Twettqet analiżi ta' tagħrif miġbur ta' rapporti ta' effetti mhux mixtieqa ta' fratturi fl-għadam minn provi kliniċi randomised, ikkontrollati b'paragun, u double blind b'aktar minn 8100 pazjent fil-gruppi kkurati b'pioglitazone u 7400 pazjent fil-gruppi kkurrati bi prodott paragun li damu sa 3.5 snin.
English: A clinical trial of pioglitazone vs. gliclazide as monotherapy was extended to two years in order to assess time to treatment failure (defined as appearance of HbA1c ≥ 8.0% after the first six months of therapy).
Maltese: Prova klinika ta' pioglitazone vs. gliclazide bħala monterapija ġiet estiża għal sentejn sabiex jiġi studjat il-ħin sal-falliment tal-kura (definit bħala ddehra ta' HbA1c ≥ 8.0% wara l-ewwel sitt xhur ta' terapija).
English: Neoplasms benign, malignant and unspecified (including cysts and polyps)
Maltese: Neoplażmi beninni, malinni u dawk mhux speċifikati (inklużi ċesti u polipi)
English: Total plasma concentration of pioglitazone is unchanged, but with an increased volume of distribution.
Maltese: Il-konċentrazzjoni totali fil-plażma ta' pioglitazone ma mbidletx, iżda b'volum ta' distribuzzjoni miżjud.
English: ul.
Maltese: L.U.
English: Part of the treatment of diabetes is dietary control.
Maltese: Parti mill-kura ta' dijabete hija kontroll tad-dieta.
English: In toxicology studies, plasma volume expansion with haemodilution, anaemia, and reversible eccentric cardiac hypertrophy was consistently apparent after repeated dosing of mice, rats, dogs, and monkeys.
Maltese: Fi studji tossikoloġiċi, l-espansjoni tal-volum tal-plażma permeżz ta' emodiluzzjoni, anemija u ipertrofija kardijaka eċċentrika riversibbli kienet apparenti b'mod konsistenti wara dożaġġ ripetut filġrieden, firien, klieb u xadini.
English: Tabulated list of adverse reactions
Maltese: LISTA TA' SUSTANZI MHUX ATTIVI
English: Pioglitazone Teva 30 mg tablets Pioglitazone
Maltese: Pioglitazone Teva 30 mg pilloli Pioglitazone
English: Pioglitazone Teva 45 mg tablets Pioglitazone
Maltese: Pioglitazone Teva 45 mg pilloli Pioglitazone
English: Fluid retention and cardiac failure
Maltese: Disturbi fis-sistema riproduttiva u fis-sider impotenza
English: Manufacturer:
Maltese: PC:
English: Pioglitazone did not cause statistically significant increases in LDL cholesterol levels compared with placebo, whilst reductions were observed with metformin and gliclazide.
Maltese: Pioglitazone ma wassalx għall-żieda statistikament sinifikanti fil-livell ta' LDL cholesterol meta mqabbel mal-plaċebo, filwaqt li tnaqqis kien osservat b'metformin u gliclazide.
English: Cardiac disorders heart failure3
Maltese: artralġja uġigħ fid-dar
English: Post marketing cases of peripheral oedema and cardiac failure have also been reported in patients with concomitant use of pioglitazone and nonsteroidal anti-inflammatory drugs, including selective COX-2 inhibitors.
Maltese: Każijiet ta' wara t-tqegħid fis-suq ta' edima periferali u kollass kardijaku ġew irrapportati wkoll f'pazjenti b'użu fl-istess ħin ta' pioglitazone u mediċini mhux sterojdali kontra linfjammazzjonijiet, inkluż inibituri ta' COX-2 selettivi.
English: Pioglitazone Teva 15 mg tablets Pioglitazone
Maltese: Pioglitazone Teva 15 mg pilloli Pioglitazone
English: Therapy with pioglitazone should not be initiated in patients with increased baseline liver enzyme levels (ALT > 2.5 X upper limit of normal) or with any other evidence of liver disease.
Maltese: Terapija b'pioglitazone m'għandiex tinbeda f'pazjenti b'livelli miżjuda ta' l-enżimi tal-fwied fil-linja bażika (ALT > 2.5 X l-għola limitu tan-normal) jew b'xi evidenza oħra ta' mard tal-fwied.
English: - Pioglitazone Teva 30 mg tablets are white to off white, round, convex with the number ‘30' on one side and ‘TEVA' on the other side.
Maltese: - Pioglitazone Teva 30 mg huma pilloli bojod għal ofwajt, tondi, mżaqqin bin-numru ‘30' fuq naħa waħda u ‘TEVA' fuq in-naħa l-oħra.
English: Almost all subjects (95%) were receiving cardiovascular medicinal products (beta blockers, ACE inhibitors, angiotensin II antagonists, calcium channel blockers, nitrates, diuretics, aspirin, statins, fibrates).
Maltese: nitrati, dijuretiċi, aspirina, statins, fibrates).
English: The European Medicines Agency has waived the obligation to submit the results of studies with pioglitazone in all subsets of the paediatric population in Type 2 Diabetes Mellitus.
Maltese: L-Aġenzija Ewropea għall-Mediċini neħħiet l-obbligu li r-riżultati ta' studji jiġu ippreżentati bil-pioglitazone fis-sottogruppi kollha tal-popolazzjoni pedjatrika ta' Tip 2 Diabetes Mellitus.
English: In PROactive, a cardiovascular outcome study, 5238 patients with type 2 diabetes mellitus and preexisting major macrovascular disease were randomised to pioglitazone or placebo in addition to existing antidiabetic and cardiovascular therapy, for up to 3.5 years.
Maltese: Fi PROactive, studju dwar l-effett kardjovaskulari, 5238 pazjent b'dijabete mellitus tat-tip 2 u b'mard makrovaskulari maġġur li kien hemm minn qabel kienu magħżula b'mod każwali għal pioglitazone jew plaċebo li kienu miżjuda ma' terapija anti-dijabetika u kardjovaskulari eżistenti, sa 3.5 snin.
English: In patients on insulin with no pioglitazone the incidence of heart failure was 8.2% in those ≥65 years compared to 4.0% in patients less than 65 years.
Maltese: F'pazjenti fuq l-insulina mingħajr pioglitazone, l-inċidenża ta' insuffiċjenza tal-qalb kienet 8.2% f'dawk ≥ 65 sena meta mqabbel ma' 4.0% f'pazjenti li għandhom inqas minn 65 sena.
English: Musculoskeletal and connective tissue disorders fracture bone4
Maltese: Disturbi muskolu skeletriċi u tat tessut konnettiv ksur ta' għadam4
English: These findings were observed across species at plasma concentrations ≤ 4 times the clinical exposure.
Maltese: Dawn is-sejbiet kienu osservati fi speċi differenti b'konċentrazzjonijiet fil-plażma ≤ 4 darbiet l espożizzjoni klinika.
English: In most clinical trials, reduced total plasma triglycerides and free fatty acids, and increased HDLcholesterol levels were observed as compared to placebo, with small, but not clinically significant increases in LDL-cholesterol levels.
Maltese: Fil-biċċa l-kbira tal-provi kliniċi, kienu osservati tnaqqis fit-triġliċeridi totali fil-plażma u fil-fatty acids ħielsa, u żieda fil-livelli ta' HDL-kolesterol meta mqabbel mal-plaċebo, b'żiediet żgħar, iżda klinikament rilevanti fil-livelli ta' LDL-kolesterol.
English: - Pioglitazone Teva 45 mg tablets are white to off white, round, convex with the number ‘45' on one side and ‘TEVA' on the other side.
Maltese: - Pioglitazone Teva 45 mg huma pilloli bojod għal ofwajt, tondi, mżaqqin bin-numru ‘45' fuq naħa waħda u ‘TEVA' fuq in-naħa l-oħra.
English: 6 In active comparator controlled trials mean weight increase with pioglitazone given as monotherapy was 2-3 kg over one year.
Maltese: Fi provi attivi kkontrollati ta' paragun, iż-żieda medja fil-piż bi pioglitazone mogħti bħala monoterapija kienet ta' 2 - 3 kg fuq medda ta' sena.
English: Others
Maltese: Ħ
English: How to take Pioglitazone Teva
Maltese: Tiħux Pioglitazone Teva
English: When Pioglitazone Teva is taken in combination with other medicines used to treat diabetes (such as insulin, chlorpropamide, glibenclamide, gliclazide, tolbutamide) your doctor will tell you whether you need to take a smaller dose of your medicines.
Maltese: Meta Pioglitazone Teva jittieħed flimkien ma' mediċini oħra wżati għall-kura tad-dijabete (bħal insulina, chlorpropamide, glibenclamide, gliclazide, tolbutamide), it-tabib tiegħek jgħidlek jekk għandekx bżonn tieħu doża inqas tal-mediċini tiegħek.
English: - Pioglitazone Teva 15 mg tablets are white to off white, round, convex with the number ‘15' on one side and ‘TEVA' on the other side.
Maltese: - Pioglitazone Teva 15 mg huma pilloli bojod għal ofwajt, tondi, mżaqqin bin-numru ‘15' fuq naħa waħda u ‘TEVA' fuq in-naħa l-oħra.
English: How to store Pioglitazone Teva Contents of the pack and other information
Maltese: Kontenut tal-pakkett u informazzjoni oħra
English: Fractures were observed in 2.6% of women taking pioglitazone compared to 1.7% of women treated with a comparator.
Maltese: Fratturi kienu osservati f'2.6% ta' nisa li kienu qed jieħdu pioglitazone meta mqabbel ma' 1.7% tan-nisa kkurati bi prodott paragun.
English: Each tablet contains 30 mg pioglitazone (as hydrochloride).
Maltese: Kull pillola fiha 30 mg pioglitazone (bħala hydrochloride).
English: Other medicines and Pioglitazone Teva
Maltese: pioglitazone u l-metabolita
English: Co-administration of pioglitazone with rifampicin (an inducer of cytochrome P450 2C8) is reported to result in a 54% decrease in AUC of pioglitazone.
Maltese: Ħija rrappurtata li l-għotja ta' pioglitazone flimkien ma' rifampicin (induttur taċ-ċitokromju P450 2C8) twassal għal tnaqqis ta' 54% fl-AUC ta' pioglitazone.
English: Pioglitazone Teva 15 mg tablets
Maltese: Pillola Pioglitazone Teva 15 mg pilloli
English: Kaplan-Meier analysis showed shorter time to treatment failure in patients treated with gliclazide, compared with pioglitazone.
Maltese: Analiżi Kaplan-Meier wriet ħin iqsar għall-falliment tal-kura f'pazjenti kkurati b'gliclazide, meta mqabbla ma' pioglitazone.
English: If jaundice is observed, the medicinal product should be discontinued.
Maltese: Jekk tkun osservata s-suffejra, il-mediċina għandha titwaqqaf.
English: Close monitoring of glycaemic control should be considered (see section 4.4).
Maltese: Sorveljanza mill-viċin tal-kontroll gliċemiku għandha tiġi kkunsidrata (ara sezzjoni 4.4).
English: - Pioglitazone is also indicated for combination with insulin in type 2 diabetes mellitus adult patients with insufficient glycaemic control on insulin for whom metformin is inappropriate because of contraindications or intolerance (see section 4.4).
Maltese: - Pioglitazone huwa indikat ukoll għall-użu flimkien ma' insulina f'pazjenti adulti b'dijabete mellitus tat-tip 2 b'kontroll gliċemiku insuffiċjenti bl-insulina u li għalihom metformin mhux adattat minħabba kontraindikazzjonijiet jew intolleranza (ara sezzjoni 4.4).
English: In an outcome study of patients with pre-existing major macrovascular disease, the incidence of serious heart failure was 1.6% higher with pioglitazone than with placebo, when added to therapy that included insulin.
Maltese: Fi studju dwar ir-riżultat f'pazjenti b'mard makrovaskulari maġġuri minn qabel, l-inċidenza ta' insuffiċjenza serja tal-qalb kienet 1.6% għola b'pioglitazone milli bilplaċebo, meta miżjud ma' terapija li tinkludi insulina.
English: Patients receiving pioglitazone had a mean reduction in HbA1c of 0.45% compared with those continuing on insulin alone, and a reduction of insulin dose in the pioglitazone treated group.
Maltese: Pazjenti li rċevew pioglitazone kellhom tnaqqis medju f'HbA1c ta' 0.45% meta mqabbel ma' dawk li komplew fuq l-insulina biss, u fil-grupp ikkurat b'pioglitazone kien hemm tnaqqis fid-doża tal-insulina.
English: Each tablet contains 15 mg pioglitazone (as hydrochloride).
Maltese: Kull pillola fiha 15 mg pioglitazone (bħala hydrochloride).
English: Frequency of adverse reactions of pioglitazone by treatment regimen
Maltese: Frekwenza ta' effetti mhux mixtieqa ta' pioglitazone b'regimen ta' trattament
English: In combination trials pioglitazone added to metformin resulted in mean weight increase over one year of 1.5 kg and added to a sulphonylurea of 2.8 kg.
Maltese: Fi provi ta' taħlita, pioglitazone miżjud ma' metformin wassal għall-żieda medja fil-piż fuq medda ta' sena ta' 1.5 kg u miżjud ma' sulphonylurea ta' 2.8 kg.
English: Pioglitazone Teva 45 mg tablets Each tablet contains 45 mg of pioglitazone (as hydrochloride).
Maltese: Kull pillola Pioglitazone Teva 45 mg fiha 45 mg ta' pioglitazone (bħala hydrochloride).
English: In this study in patients receiving pioglitazone and insulin, a higher percentage of patients with heart failure was observed in patients aged ≥65 years compared with those less than 65 years (9.7% compared to 4.0%).
Maltese: F'dan l-istudju f'pazjenti li qed jirċievu pioglitazone u l-insulina, kien osservat perċentwal ogħla ta' pazjenti b'insuffiċjenza tal-qalb f'pazjenti li għandhom ≥ 65 sena meta mqabbla ma'dawk iżgħar minn 65 sena (9.7% meta mqabbla ma' 4.0%).
English: Almost half of the patients had a previous myocardial infarction and approximately 20% had had a stroke.
Maltese: Kważi nofs il-pazjenti kellhom minn qabel infart mijokardijaku u madwar 20% kellhom puplesija.
English: There have been rare reports of hepatocellular dysfunction during post-marketing experience (see section 4.8).
Maltese: Kien hemm rapporti rari ta' disfunzjoni epatoċellolari waqt l-esperjenza ta' wara t-tqegħid fis-suq (ara sezzjoni 4.8).
English: Pioglitazone treatment may be initiated at 15 mg or 30 mg once daily.
Maltese: Il-kura bi pioglitazone tista' tinbeda b'15 mg jew 30 mg darba kuljum.
English: Pioglitazone should be used with caution during concomitant administration of cytochrome P450 2C8 inhibitors (e.g. gemfibrozil) or inducers (e.g. rifampicin).
Maltese: Pioglitazone għandu jintuża b'attenzjoni waqt l-għotja fl-istess ħin ta' inibituri (e.ż. gemfibrozil) jew indutturi (e.ż. rifampicin) taċ-ċitokromju P450 2C8.
English: It is an anti-diabetic medicine used to treat type 2 (noninsulin dependent) diabetes mellitus in adults, when metformin is not suitable or has failed to work adequately.
Maltese: Huma mediċina antidijabetika użata biex tikkura dijabete mellitus tat-tip 2 (mhux dipendenti mill-insulina) fl-adulti, meta metformin ma jkunx xieraq jew ikun naqas li jaħdem b'mod adegwat.
English: common (may affect up to 1 in 10 people) - headache - dizziness - joint pain - impotence - back pain - shortness of breath - small reduction in red blood cell count - flatulence uncommon (may affect up to 1 in 100 people) - sugar in urine, proteins in urine - increase in enzymes - spinning sensation (vertigo) - sweating - tiredness - increased appetite
Maltese: Madankollu, ċerti mediċini huma speċjalment probabbli li jaffettwaw l-ammont ta' zokkor fid-demm tiegħek: - gemfibrizol (użati biex ibaxxu l-kolesterol) - rifampicin (jintużaw biex jikkuraw it-tuberkulożi u infezzjonijiet oħra) Għid lit-tabib jew spiżjar tiegħek jekk qed tieħu xi wieħed minn dawn.
English: Each tablet contains 45 mg pioglitazone (as hydrochloride).
Maltese: Kull pillola fiha 45 mg pioglitazone (bħala hydrochloride).
English: Pioglitazone Teva 30 mg tablets Each tablet contains 30 mg of pioglitazone (as hydrochloride).
Maltese: Kull pillola Pioglitazone Teva 30 mg fiha 30 mg ta' pioglitazone (bħala hydrochloride).
English: In a placebo controlled trial, patients with inadequate glycaemic control despite a three month insulin optimisation period were randomised to pioglitazone or placebo for 12 months.
Maltese: Fi prova kkontrollata bil-plaċebo, pazjenti b'kontroll gliċemiku inadegwat minkejja perjodu ta' ottimizzazzjoni b'insulina ta' 3 xhur, kienu randomised għal pioglitazone jew plaċebo għal 12-il xahar.
English: In the 3.5 year PROactive study, 44/870 (5.1%) of pioglitazone-treated female patients experienced fractures compared to 23/905 (2.5%) of female patients treated with comparator.
Maltese: Fl-istudju PROactive ta' 3.5 snin, 44/870 (5.1%) tal-pazjenti nisa kkurati b'pioglitazone kellhom esperjenza ta' fratturi meta mqabbel ma'
English: METHOD AND ROUTE(S) OF ADMINISTRATION
Maltese: L-KITBA (MM/YYYY)
English: The fracture incidence calculated was 1.9 fractures per 100 patient years in women treated with pioglitazone and 1.1 fractures per 100 patient years in women treated with a comparator.
Maltese: L-inċidenza ta' fratturi kkalkulata kienet ta' 1.9 fratturi kull 100 sena ta' pazjent f'nisa kkurati b'pioglitazone u 1.1 fratturi kull 100 sena ta' pazjent f'nisa kkurati bi prodott ta' paragun.
English: Although the study failed regarding its primary endpoint, which was a composite of all-cause mortality, non-fatal myocardial infarction, stroke, acute coronary syndrome, major leg amputation, coronary revascularisation and leg revascularisation, the results suggest that there are no long-term cardiovascular concerns regarding use of pioglitazone.
Maltese: Għalkemm l-istudju falla fil-mira primarja tiegħu, li kienet magħmula mill-kawżi kollha ta' mortalità, infart mijokariku mhux fatali, puplesija, sindromu koronarju akut, amputazzjoni maġġura tas-sieq,
English: Pioglitazone Teva 15 mg tablets Each tablet contains 15 mg of pioglitazone (as hydrochloride).
Maltese: Kull pillola Pioglitazone Teva 15 mg fiha 15 mg ta' pioglitazone (bħala hydrochloride).
English: Similar changes in body fat distribution on pioglitazone have been accompanied by an improvement in insulin sensitivity.
Maltese: Tibdiliet simili fid-distribuzzjoni tax-xaħam fil-ġisem b'pioglitazone saru flimkien ma' titjib fis-sensittività għall-insulina.
English: Respiratory, thoracic and mediastinal disorders dyspnoea common
Maltese: - infezzjoni respiratorja - vista mhux normali
English: Patients should be aware of the risk of pregnancy and if a patient wishes to become pregnant or if pregnancy occurs, the treatment should be discontinued (see section 4.6).
Maltese: Il-pazjenti għandhom ikunu konxji tar-riskju ta' tqala u jekk il-pazjenta tixtieq tinqabad tqila jew jekk it-tqala sseħħ, il-kura għandha titwaqqaf (ara sezzjoni 4.6).
English: Medicinal product subject to medical prescription.
Maltese: EFFETTIV TAL-PRODOTT MEDIĊINALI
English: As a consequence of increased insulin sensitivity, patients receiving pioglitazone in dual or triple oral therapy with a sulphonylurea or in dual therapy with insulin may be at risk for dose-related hypoglycaemia, and a reduction in the dose of the sulphonylurea or insulin may be necessary.
Maltese: Ipogliċemija Bħala konsegwenza ta' żieda fis-sensittività għall-insulina, pazjenti li qed jirċievu pioglitazone f'terapija mill-ħalq doppja jew trippla ma' mediċina tat-tip sulphonylurea jew f'terapija doppja mal insulina jistgħu jkunu f'riskju ta' ipogliċemija relatat mad-doża, u tista' tkun neċessarja tnaqqis fid doża tal-mediċina tat-tip sulphonylurea jew tal-insulina.
English: In patients with renal impairment, plasma concentrations of pioglitazone and its metabolites are lower than those seen in subjects with normal renal function, but oral clearance of parent substance is similar.
Maltese: F'pazjenti b'indeboliment renali, il-konċentrazzjonijiet fil-plażma ta' pioglitazone u l-metaboliti tiegħu huma inqas minn dawk li dehru f'soġġetti b'funzjoni renali normali, iżda t-tneħħija mill-ħalq tas-sustanża oriġinali hija simili.
English: Following oral administration of radiolabelled pioglitazone to man, recovered label was mainly in faeces (55%) and a lesser amount in urine (45%).
Maltese: Eliminazzjoni Wara għotja mill-ħalq ta' pioglitazone radjulabiljat lill-bniedem, it-tikkettjar miġbur kien l-aktar fil feċi (55%) u f'ammont inqas fl-awrina (45%).
English: Pioglitazone should be discontinued if any deterioration in cardiac status occurs.
Maltese: - insuffiċjenza kardijaka jew passat ta' insuffiċjenza kardijaka (NYHA stadju I sa IV).
English: The observed excess risk of fractures for women in this dataset on pioglitazone is therefore 0.8 fractures per 100 patient years of use.
Maltese: Iż-żieda osservata fir-riskju ta' fratturi għan-nisa f'dan id-dataset fuq pioglitazone għalhekk huwa ta' 0.8 fratturi kull 100 sena ta' pazjent ta' użu.
English: Teva UK Ltd Brampton Road, Hampden Park, Eastbourne,
Maltese: Brampton Road, Hampden Park, Eastbourne, East Sussex, BN22 9AG Ir-Renju Unit
English: Hypoglycaemia
Maltese: FARMAĊEWTIKU
English: Pregnancy and breast-feeding
Maltese: Kanċer fil-bużżieqa
English: common (may affect up to 1 in 10 people) - respiratory infection - abnormal vision - weight gain - numbness uncommon (may affect up to 1 in 100 people) - inflammation of the sinuses (sinusitis) - difficulty sleeping (insomnia)
Maltese: Il-frekwenzi huma definiti bħala: komuni ħafna (≥ 1/10); komuni (≥ 1/100 sa < 1/10); mhux komuni (≥ 1/1,000 sa
English: 7 In clinical trials with pioglitazone the incidence of elevations of ALT greater than three times the upper limit of normal was equal to placebo but less than that seen in metformin or sulphonylurea comparator groups.
Maltese: 7 Fi provi kliniċi b'pioglitazone l-inċidenża ta' elevazzjonijiet ta' ALT aktar minn tlett darbiet l-għola limitu tan-normal kienet daqs il-plaċebo iżda inqas minn dik li deheret fil-grupp ta' paragun b'metformin jew b'sulphonylurea.
English: Package leaflet: Information for the user Pioglitazone Teva 15 mg tablets
Maltese: • Il-pakkett edukattiv tabib għandu jkun fih:
English: What you need to know before you take Pioglitazone Teva Do not take Pioglitazone Teva
Maltese: M'hemmx dejta biżżejjed fil-bniedem sabiex tiġi determinata is-sigurtà ta' pioglitazone waqt it-tqala.
English: Pioglitazone and all active metabolites are extensively bound to plasma protein (> 99%).
Maltese: Pioglitazone u l-metaboliti attivi kollha huma marbuta b'mod estensiv mal-proteini fil-plażma (>
English: ALPHA 1-ADRENORECEPTOR ANTAGONIST Alfuzosin
Maltese: ALPHA 1-ADRENORECEPTOR Alfuzosin