FrancophonIA/ELRC3.0 huggingface dataset:
English: These symptoms are usually not serious and disappear within a few days, but if you have symptoms that are troublesome you should ask your doctor for advice.
Slovenian: Ti simptomi običajno niso resni in v nekaj dneh izzvenijo, vendar se posvetujte s svojim zdravnikom, če imate simptome, ki vam povzročajo težave.
English: Duloxetine had no effect on male fertility, and effects in females were only evident at doses that caused maternal toxicity.
Slovenian: Duloksetin ni vplival na plodnost pri moških, pri ženskah pa so bili učinki opaženi le pri odmerkih, ki so povzročili toksičnost za mater.
English: If your doctor has prescribed Xeristar for a patient under 18 and you want to discuss this, please go back to your doctor.
Slovenian: Če je vaš zdravnik predpisal zdravilo Xeristar bolniku, mlajšemu od 18 let, in se želite o tem pogovoriti, se, prosimo,
English: What Xeristar is and what it is used for What you need to know before you take Xeristar How to take Xeristar
Slovenian: Kaj je zdravilo Xeristar in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Xeristar Kako jemati zdravilo Xeristar
English: Do not start or stop taking any medicines, including those bought without a prescription and herbal remedies, before checking with your doctor.
Slovenian: Ne začnite jemati niti ne prenehajte jemati katerihkoli zdravil, vključno s tistimi, ki ste jih kupili brez recepta, in pripravkov rastlinskega izvora, ne da bi se pred tem posvetovali s svojim zdravnikom.
English: Only a small proportion of patients included in pivotal clinical trials had severe depression (baseline HAM-D>25).
Slovenian: Le majhen delež bolnikov, sodelujočih v presečnih kliničnih preskušanjih, je imel hudo depresijo (izhodiščno število točk po HAM-D > 25).
English: If your doctor thinks that you no longer need Xeristar he or she will ask you to reduce your dose over at least 2 weeks before stopping treatment altogether.
Slovenian: Če bo vaš zdravnik menil, da zdravila Xeristar ne potrebujete več, vam bo naročil/naročila, da pred prenehanjem zdravljenja 2 tedna postopoma znižujte svoj odmerek.
English: Despite this, your doctor may prescribe Xeristar for patients under 18 because he/she decides that this is in their best interests.
Slovenian: Temu navkljub lahko vaš zdravnik predpiše zdravilo Xeristar tudi bolnikom, mlajšim od 18 let, če se odloči, da je to v njihovo najboljšo korist.
English: Also, the long-term safety effects concerning growth, maturation, and cognitive and behavioural development of Xeristar in this age group have not yet been demonstrated.
Slovenian: Dolgoročni učinki zdravila Xeristar na varnost glede rasti, dozorevanja in kognitivnega ter vedenjskega razvoja v tej starostni skupini tudi še niso bili ugotovljeni.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
Slovenian: Obvestite svojega zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali, ali pa boste morda začeli jemati katerokoli zdravilo, tudi če ste ga dobili brez recepta.
English: Other medicines and Xeristar
Slovenian: Druga zdravila in zdravilo Xeristar
English: Elimination: The elimination half-life of duloxetine ranges from 8 to 17 hours (mean of 12 hours).
Slovenian: Izločanje: Razpolovni čas izločanja duloksetina je od 8 do 17 ur (povprečno 12 ur).
English: Your doctor may continue to give you Xeristar when you are feeling better to prevent your depression or anxiety from returning.
Slovenian: Vaš zdravnik vam bo morda še naprej predpisoval zdravilo Xeristar, tudi ko se boste že bolje počutili, da bi preprečil ponoven pojav depresije ali anksioznosti.
English: The dose may be adjusted up to 120 mg a day based on your response to Xeristar.
Slovenian: Odmerek bo morda prilagojen do 120 mg na dan, glede na vaš odziv na zdravilo Xeristar.
English: Xeristar starts to work in most people with depression or anxiety within two weeks of starting treatment, but it may take 2-4 weeks before you feel better.
Slovenian: Pri večini bolnikov z depresijo ali anksioznostjo začne zdravilo Xeristar delovati v dveh tednih po začetku zdravljenja, lahko pa traja 2 do 4 tedne, preden se boste počutili boljše.
English: Do not stop taking Xeristar, or change your dose, without talking to your doctor.
Slovenian: Ne prenehajte jemati zdravila Xeristar in ne spreminjajte odmerka, ne da bi se posvetovali s svojim zdravnikom.
English: Your doctor should decide whether you can take Xeristar with other medicines.
Slovenian: Vaš zdravnik se mora odločiti, ali lahko jemljete zdravilo Xeristar z drugimi zdravili.
English: However, as with any medicine, caution should be exercised when treating the elderly, especially with Xeristar 120 mg per day for major depressive disorder or generalised anxiety disorder, for which data are limited (see sections 4.4 and 5.2).
Slovenian: Vendar pa je, kot pri vseh zdravilih, pri zdravljenju starejših potrebna previdnost, posebno z zdravilom Xeristar 120 mg na dan za zdravljenje velike depresivne motnje ali generalizirane anksiozne motnje, za kar je na voljo malo podatkov (glejte poglavji 4.4 in 5.2).
English: SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS
Slovenian: POSEBNI VARNOSTNI UKREPI ZA ODSTRANJEVANJE NEUPORABLJENIH
English: The absolute oral bioavailability of duloxetine ranged from 32% to 80% (mean of 50%).
Slovenian: Absolutna peroralna biološka uporabnost duloksetina dosega vrednosti od 32 do 80 % (povprečje 50
English: The main ingredient of Xeristar, duloxetine, is used in other medicines for other conditions:
Slovenian: Poglavitno sestavino zdravila Xeristar, duloksetin, uporabljamo tudi v drugih zdravilih za zdravljenje drugih bolezni:
English: Gender: Pharmacokinetic differences have been identified between males and females (apparent plasma clearance is approximately 50% lower in females).
Slovenian: Spol: med moškimi in ženskami so ugotovili farmakokinetične razlike (očitni plazemski očistek je pri ženskah približno 50 % nižji).
English: Clinical efficacy and safety
Slovenian: Učinkovitost in varnost zdravila
English: In people with diabetic neuropathic pain it can take some weeks before you feel better.
Slovenian: Pri bolnikih z bolečino diabetične nevropatije lahko pa traja več tednov, preden se vaše počutje izboljša.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Slovenian: Zahteve glede predložitve redno posodobljenega poročila o varnosti zdravila za to zdravilo so določene v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7)
English: • If you take Xeristar near the end of your pregnancy there is an increased risk of excessive vaginal bleeding shortly after birth, especially if you have a history of bleeding disorders.
Slovenian: • Če zdravilo Xeristar jemljete proti koncu nosečnosti, obstaja povečano tveganje za čezmerno krvavitev iz nožnice kmalu po porodu, sploh če ste v preteklosti že imeli motnje strjevanja krvi.
English: Hepatic impairment: Moderate liver disease (Child Pugh Class B) affected the pharmacokinetics of duloxetine.
Slovenian: Okvarjeno delovanje jeter: zmerno okvarjeno delovanje jeter (razred Child Pugh B) je vplivalo na farmakokinetiko duloksetina.
English: See section 4..
Slovenian: Glejte poglavje 4.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Xeristar in all subsets of the paediatric population in the treatment of major depressive disorder, diabetic neuropathic pain and generalised anxiety disorder.
Slovenian: Evropska agencija za zdravila je začasno odložila obvezo za predložitev rezultatov študij z zdravilom Xeristar za vse skupine pediatrične populacije pri zdravljenju velike depresivne motnje, bolečine diabetične nevropatije in generalizirane anksiozne motnje.
English: Xeristar increases the levels of serotonin and noradrenaline in the nervous system.
Slovenian: Zdravilo Xeristar zviša nivo serotonina in noradrenalina v živčnem sistemu.
English: Inducers of CYP1A2: Population pharmacokinetic analyses have shown that smokers have almost 50% lower plasma concentrations of duloxetine compared with non-smokers.
Slovenian: Induktorji CYP1A2: študije populacijske farmakokinetike so pokazale, da imajo kadilci v primerjavi z nekadilci skoraj za 50 % nižje plazemske koncentracije duloksetina.
English: Data on the use of Xeristar 120 mg in elderly patients with major depressive disorder and generalised anxiety disorder are limited.
Slovenian: Podatkov o uporabi zdravila Xeristar 120 mg pri starejših bolnikih z veliko depresivno motnjo in generalizirano anksiozno motnjo je malo.
English: • If you take Xeristar near the end of your pregnancy, your baby might have some symptoms when it is born.
Slovenian: • Če zdravilo Xeristar jemljete proti koncu nosečnosti, se lahko po rojstvu pri vašem otroku pojavijo nekateri simptomi.
English: Xeristar may cause a sensation of restlessness or an inability to sit or stand still.
Slovenian: Zdravilo Xeristar lahko povzroči občutek nemira ali nezmožnosti sedenja ali stanja pri miru.
English: Use in children and adolescents under 18 years of age Xeristar should not be used in the treatment of children and adolescents under the age of 18 years.
Slovenian: Uporaba pri otrocih in mladostnikih, mlajših od 18 let Zdravila Xeristar pri zdravljenju otrok in mladostnikov, mlajših od 18 let, ne smemo uporabljati.
English: Hyponatraemia may be due to a syndrome of inappropriate anti-diuretic hormone secretion (SIADH).
Slovenian: Hiponatriemija je lahko posledica sindroma neustreznega izločanja antidiuretičnega hormona (syndrome of inappropriate anti-diuretic hormone secretion, SIADH).
English: In general, the adverse reaction profile of duloxetine in children and adolescents was similar to that seen for adults.
Slovenian: V splošnem je bil profil neželenih učinkov duloksetina pri otrocih in mladostnikih podoben tistemu pri odraslih.
English: The initiation of treatment with Xeristar is contraindicated in patients with uncontrolled hypertension that could expose patients to a potential risk of hypertensive crisis (see sections 4.4 and 4.8).
Slovenian: Uvedba zdravljenja z zdravilom Xeristar je kontraindicirana pri bolnikih z nenadzorovano hipertenzijo, ki lahko izpostavi bolnike možnemu tveganju za hipertenzivno krizo (glejte poglavje 4.4 in 4.8).
English: When stopping treatment with Xeristar the dose should be gradually reduced over a period of at least one to two weeks in order to reduce the risk of withdrawal reactions (see sections 4.4 and 4.8).
Slovenian: Ob prenehanju zdravljenja z zdravilom Xeristar je treba odmerek zdravila v obdobju najmanj enega do dveh tednov postopoma zmanjševati, da zmanjšamo tveganje za pojav odtegnitvenih reakcij (glejte poglavji 4.4 in 4.8).
English: You should inform your doctor if any of the symptoms listed above develop or worsen when patients under 18 are taking Xeristar.
Slovenian: Svojega zdravnika obvestite, če se kateri od zgoraj naštetih simptomov pri bolniku, mlajšemu od 18 let, ki jemlje zdravilo Xeristar, pojavi ali poslabša.
English: Do not take more than the daily amount of Xeristar that has been prescribed for you in one day.
Slovenian: Ne zaužijte več zdravila Xeristar v enem dnevu, kot vam je bilo predpisano.
English: Xeristar may be associated with sedation and dizziness.
Slovenian: Zdravilo Xeristar je lahko povezano s sedacijo in omotico.
English: Talk with your doctor about how long you should keep taking Xeristar.
Slovenian: S svojim zdravnikom se pogovorite o tem, kako dolgo boste jemali zdravilo Xeristar.
English: Xeristar 60 mg is available in packs of 28, 56, 84, 98, 100 and 500 capsules.
Slovenian: Zdravilo Xeristar 60 mg je na voljo v pakiranjih po 28, 56, 84, 98, 100 in 500 kapsul.
English: Xeristar is available in 2 strengths: 30 mg and 60 mg.
Slovenian: Zdravilo Xeristar je na voljo v dveh jakostih: 30 mg in 60 mg.
English: Both cytochromes P450-2D6 and 1A2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine and sulfate conjugate of 5-hydroxy 6-methoxy duloxetine.
Slovenian: P450-2D6 in 1A2, katalizirata tvorbo dveh poglavitnih presnovkov glukuronidnega konjugata 4hidroksi duloksetina in sulfatnega konjugata 5-hidroksi 6-metoksi duloksetina.
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Slovenian: Če vam je vaš zdravnik povedal, da ne prenašate nekaterih sladkorjev, se pred jemanjem tega zdravila pogovorite z njim.
English: If you take more Xeristar than you should
Slovenian: Če ste vzeli večji odmerek zdravila Xeristar, kot bi smeli
English: • Make sure your midwife and/or doctor knows you are on Xeristar.
Slovenian: • Svoji medicinski sestri, babici in/ali zdravniku povejte, da jemljete zdravilo Xeristar.
English: Major Depressive Disorder: Xeristar was studied in a clinical programme involving 3,158 patients (1,285 patient-years of exposure) meeting DSM-IV criteria for major depression.
Slovenian: Klinična učinkovitost in varnost Velike depresivne motnje: Zdravilo Xeristar so preučevali v kliničnem programu, v katerem je sodelovalo 3.158 bolnikov (1.285 bolniških let izpostavljenosti), ki so izpolnjevali merila DSM-IV za veliko depresivno motnjo.
English: Breast-feeding mothers: The disposition of duloxetine was studied in 6 lactating women who were at least 12-weeks postpartum.
Slovenian: Doječe matere: Odlaganje duloksetina so preučevali pri 6 doječih ženskah v obdobju najmanj 12 tednov po porodu.
English: • Tell your doctor if you become pregnant, or you are trying to become pregnant, while you are taking Xeristar.
Slovenian: • Obvestite svojega zdravnika, če zanosite ali poskušate zanositi, medtem ko jemljete zdravilo
English: Table 1 gives the adverse reactions observed from spontaneous reporting and in placebo-controlled clinical trials.
Slovenian: Preglednica 1 prikazuje neželene učinke, ki so jih opažali v spontanih poročanjih in v s placebom kontroliranih kliničnih preskušanjih..
English: • Xeristar may cause effects that you may not be aware of, such as increases in liver enzymes or blood levels of potassium, creatine phosphokinase, sugar, or cholesterol
Slovenian: • zvečanje telesne mase • Xeristar lahko povzroči tudi neželene učinke, ki se jih morda ne zavedate, kot povišanje jetrnih encimov ali krvnega nivoja kalija, kreatinske fosfokinaze, sladkorja ali holesterola.
English: OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF APPROPRIATE
Slovenian: ZDRAVIL ALI IZ NJIH NASTALIH ODPADNIH SNOVI, KADAR SO POTREBNI
English: In both studies, Xeristar 60 mg once daily and 60 mg twice daily significantly reduced pain compared with placebo.
Slovenian: V obeh študijah je zdravilo Xeristar 60 mg enkrat na dan in 60 mg dvakrat na dan značilno zmanjšal bolečino v primerjavi s placebom.
English: Duloxetine may increase the risk of postpartum haemorrhage (see section 4.6).
Slovenian: Duloksetin lahko poveča tveganje za poporodno krvavitev (glejet poglavje 4.6).
English: You must wait at least 14 days after you have stopped taking an MAOI before you can take Xeristar.
Slovenian: Po prenehanju jemanja MAOI morate počakati vsaj 14 dni, preden lahko vzamete zdravilo Xeristar.
English: Hallucinations Aggression and anger4
Slovenian: manija halucinacije agresija in jeza5
English: • coughing, wheezing and shortness of breath which may be accompanied by a high temperature
Slovenian: • kašelj, piskanje v pljučih in zadihanost, ki jih lahko spremlja visoka telesna temperatura
English: Hypertension3,7 Orthostatic hypotension2 Peripheral coldness
Slovenian: Hipertenzija3,7 ortostatska hipotenzija2 hladni periferni deli hipertenzivna kriza3,6
English: Absorption: Duloxetine is well absorbed after oral administration with a Cmax occurring 6 hours post dose.
Slovenian: Absorpcija: Duloksetin se po peroralnem jemanju dobro absorbira s pojavom Cmax 6 ur po odmerjanju.
English: Xeristar should be used with caution in patients with a history of mania or a diagnosis of bipolar disorder, and/or seizures.
Slovenian: Zdravilo Xeristar je treba pri bolnikih z manijo v anamnezi ali z diagnozo bipolarne motnje in/ali epileptičnimi napadi uporabljati previdno.
English: Biotransformation: Duloxetine is extensively metabolised and the metabolites are excreted principally in urine.
Slovenian: Presnova: Duloksetin se obsežno presnavlja, presnovki se izločajo predvsem v urinu.
English: No studies on the effects on the ability to drive and use machines have been performed.
Slovenian: 4.7 Vpliv na sposobnost vožnje in upravljanja strojev Študij vpliva na sposobnost vožnje in upravljanja strojev niso izvedli.
English: Generalised Anxiety Disorder: Xeristar demonstrated statistically significant superiority over placebo in five out of five studies including four randomised, double-blind, placebo-controlled acute studies and a relapse prevention study in adult patients with generalised anxiety disorder.
Slovenian: Generalizirana anksiozna motnja: zdravilo Xeristar se je izkazalo za statistično značilno boljšo kot placebo v petih izmed petih študij, vključno s štirimi randomiziranimi, dvojno slepimi, s placebom kontroliranimi akutnimi študijami in študijo preprečevanja relapsa pri odraslih bolnikih z generalizirano anksiozno motnjo.
English: Xeristar should not be used in combination with fluvoxamine, ciprofloxacin or enoxacin (i.e. potent CYP1A2 inhibitors) since the combination results in elevated plasma concentrations of duloxetine (see section 4.5).
Slovenian: Zdravila Xeristar ne smemo uporabljati v kombinaciji s fluvoksaminom, ciprofloksacinom ali enoksacinom (tj. močnimi zaviralci CYP1A2), saj kombinacija povzroči povišane plazemske koncentracije duloksetina (glejte poglavje 4.5).
English: Xeristar showed comparable efficacy results to venlafaxine in terms of improvements on the HAM-A total score.
Slovenian: Zdravilo Xeristar je pokazalo primerljive rezultate učinkovitosti v primerjavi z venlafaksinom glede izboljšanja skupnega števila točk po HAM
English: 10Estimated frequency based on placebo-controlled clinical trials.
Slovenian: 10Ocenjena pogostnost na podlagi kliničnih preskušanj, nadzorovanih s placebom.
English: If you forget to take Xeristar
Slovenian: Če ste pozabili vzeti zdravilo Xeristar
English: Care should be taken if you drink alcohol while you are being treated with Xeristar.
Slovenian: Bodite posebej previdni, če med zdravljenjem z zdravilom Xeristar pijete alkohol.
English: Diabetic Peripheral Neuropathic Pain: The efficacy of Xeristar as a treatment for diabetic neuropathic pain was established in 2 randomised, 12-week, double-blind, placebo-controlled, fixed dose studies in adults (22 to 88 years) having diabetic neuropathic pain for at least 6 months.
Slovenian: Bolečina diabetične periferne nevropatije: učinkovitost zdravila Xeristar kot zdravila za bolečino pri diabetični nevropatiji so ugotavljali v 2 randomiziranih 12-tedenskih dvojno slepih s placebom kontroliranih študijah z določenim odmerkom pri odraslih (starih od 22 do 88 let), ki so imeli bolečino diabetične nevropatije vsaj 6 mesecev.
English: Duloxetine is a combined serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor.
Slovenian: Duloksetin je kombinirani zaviralec prevzema serotonina (5-HT) in noradrenalina (NA).
English: Each capsule of Xeristar contains pellets of duloxetine hydrochloride with a covering to protect them from stomach acid.
Slovenian: Vsaka kapsula zdravila Xeristar vsebuje pelete duloksetinijevega klorida z oblogo za zaščito pred želodčno kislino.
English: If you stop taking Xeristar
Slovenian: Če ste prenehali jemati zdravilo Xeristar
English: Tolerability of Xeristar 60 mg once daily in elderly patients was comparable to that seen in the younger adults.
Slovenian: Prenašanje zdravila Xeristar 60 mg enkrat na dan pri starejših bolnikih je bilo primerljivo s tistim, ki je bilo opaženo pri mlajših odraslih.
English: Renal impairment: End stage renal disease (ESRD) patients receiving dialysis had 2-fold higher duloxetine Cmax and AUC values compared with healthy subjects.
Slovenian: Okvarjeno delovanje ledvic: bolniki s končno odpovedjo ledvic v programu dialize so imeli 2-krat višje vrednosti Cmax in AUC duloksetina v primerjavi z zdravimi osebami.
English: The most commonly reported adverse reactions in patients treated with Xeristar were nausea, headache, dry mouth, somnolence, and dizziness.
Slovenian: Neželeni učinki, o katerih so pri bolnikih, zdravljenih z zdravilom Xeristar, najpogosteje poročali, so bili slabost, glavobol suha usta, zaspanost in omotica.
English: Treatment with duloxetine showed a statistically significantly greater improvement in GAD symptoms, as measured by PARS severity score for GAD (mean difference between duloxetine and placebo of 2.7 points [95% CI 1.3-4.0]), after 10 weeks of treatment.
Slovenian: Zdravljenje z duloksetinom je pokazalo statistično pomembnejše veliko izboljšanje simptomov generalizirane anksiozne motnje, merjeno z lestvico PARS izraženosti simptomov generalizirane anksiozne motnje (povprečna razlika med duloksetinom in placebom je znašala 2,7 točke [95% IZ 1,3-4,0]), po 10 tednih zdravljenja.
English: Xeristar is indicated in adults.
Slovenian: Zdravilo Xeristar je indicirano za zdravljenje odraslih.
English: Xeristar should normally not be used for children and adolescents under 18 years.
Slovenian: Zdravila Xeristar pri otrocih in mladostnikih, mlajših od 18 let, običajno ne uporabljamo.
English: Hyponatraemia has been reported when administering Xeristar, including cases with serum sodium lower than 110 mmol/l.
Slovenian: Ob dajanju zdravila Xeristar so poročali o hiponatriemiji, vključno s primeri, ko je bila serumska koncentracija natrija pod 110 mmol/l.
English: However, data on elderly patients exposed to the maximum dose (120mg per day) are limited and thus, caution is recommended when treating this population.
Slovenian: Vendar pa je podatkov pri starejših bolnikih, ki so bili izpostavljeni maksimalnemu odmerku (120 mg na dan) malo, in je zato pri zdravljenju te populacije potrebna previdnost.
English: If you have thoughts of harming or killing yourself at any time, contact your doctor or go to a hospital straight away.
Slovenian: Če kadarkoli začnete razmišljati o samopoškodovanju ali samomoru, se nemudoma posvetujte s svojim zdravnikom ali poiščite pomoč v najbližji bolnišnici.
English: • fainting, dizziness, lightheadedness or fainting on standing up, cold fingers and/or toes
Slovenian: • omedlevica, omotica, občutek omotičnosti ali omedlevice ob prehitrem vstajanju, občutek mraza v prstih in/ali prstih na nogah
English: Xeristar hard gastro-resistant capsules contain sucrose.
Slovenian: Xeristar trde gastrorezistentne kapsule vsebujejo saharozo.
English: In clinical trials adverse events seen on abrupt treatment discontinuation occurred in approximately 45% of patients treated with Xeristar and 23% of patients taking placebo.
Slovenian: V kliničnih preskušanjih so se neželeni učinki ob nenadni prekinitvi zdravljenja pojavili pri približno 45 % bolnikov, ki so jemali zdravilo Xeristar in pri 23 % bolnikov, ki so dobivali placebo.
English: The antibiotic linezolid is a reversible non-selective MAOI and should not be given to patients treated with Xeristar (see section 4.4).
Slovenian: Antibiotik linezolid je reverzibilen, neselektiven MAOI in ga bolniki, zdravljeni z zdravilom Xeristar, ne smejo prejemati (glejte poglavje 4.4).
English: Consequently, caution is advised when Xeristar is taken in combination with other centrally acting medicinal products or substances, including alcohol and sedative medicinal products (e.g. benzodiazepines, morphinomimetics, antipsychotics, phenobarbital, sedative antihistamines).
Slovenian: Xeristar v kombinaciji z drugimi centralno delujočimi zdravili ali snovmi, ki vključujejo alkohol in pomirjevala (denimo benzodiazepini, morfinomimetiki, antipsihotiki, fenobarbital, sedirajoči antihistaminiki), potrebna previdnost.