FrancophonIA/ELRC3.0 huggingface dataset:
English: 7 to < 15 kg
Danish: 7 til < 15 kg
English: Anticancer
Danish: Midler mod cancer
English: • inflammation of blood vessels and capillaries;
Danish: • betændelse i blodkar og kapillærer;
English: The mean (SD) for the studies are reported in the table below.
Danish: Gennemsnit (SD) fremgår af nedenstående tabel.
English: The syringe has two main parts, a ‘plunger' and a ‘barrel'.
Danish: Sprøjten har to primære dele, et stempel og en sprøjtecylinder.
English: • deep vein inflammation related to a blood clot;
Danish: • dyb venebetændelse i forbindelse med en blodprop;
English: Cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to combination antiretroviral therapy (CART).
Danish: Der er rapporteret om tilfælde af osteonekose, især hos patienter med almindeligt anerkendte risikofaktorer, fremskreden hiv-sygdom eller langvarig eksponering for CART.
English: Please refer to the Aptivus Summary of Product Characteristics for additional information on the use of tipranavir, including genotypic predictors of response, in treatment of lopinavir-resistant HIV-1 infection.
Danish: Se produktresuméet for Aptivus for yderligere information om anvendelsen af tipranavir, inklusive genotype forudsigelse af respons, i behandling af lopinavir-resistent hiv-1-infektion.
English: Antimycobacterials Bedaquiline (single dose)
Danish: Antibiotika med virkning på mykobakterier Bedaquilin (enkelt-dosis)
English: Lopinavir can be used during pregnancy if clinically needed.
Danish: Hvis det er klinisk nødvendigt, kan lopinavir bruges til gravide.
English: The in vitro antiviral activity of lopinavir against laboratory and clinical HIV strains was evaluated in acutely infected lymphoblastic cell lines and peripheral blood lymphocytes, respectively.
Danish: Lopinavirs antivirale effekt mod laboratorie og kliniske hiv-stammer in vitro er undersøgt i henholdsvis akut inficerede lymfoblast cellelinjer og periferale blod lymfocytter.
English: Particular caution should be used when prescribing sildenafil or tadalafil for the treatment of erectile dysfunction in patients receiving Kaletra.
Danish: Der bør udvises særlig forsigtighed, når sildenafil eller tadalafil ordineres til behandling af erektil dysfunktion hos patienter, som får Kaletra.
English: Turn the syringe so that the tip is pointing up, gently tap it and push plunger to remove any air bubbles.
Danish: Vend sprøjten så spidsen peger opad, slå let på den og tryk på stemplet for at fjerne luftbobler.
English: When Kaletra is administered concomitantly with bosentan, the efficacy of the HIV therapy should be monitored and patients should be closely observed for bosentan toxicity, especially during the first week of co-administration.
Danish: Når Kaletra administeres samtidig med bosentan, bør effekten af hiv-behandlingen overvåges, og patienterne bør følges tæt og overvåges for bosentan-toksicitet, især i de første uger af den samtidige behandling.
English: • non-nucleoside reverse transcriptase inhibitors (NNRTIs) (e.g. efavirenz, nevirapine);
Danish: • non-nukleosid revers transkriptasehæmmere (NNRTIs) (f.eks. efavirenz, nevirapin);
English: Nucleoside/Nucleotide reverse transcriptase inhibitors (NRTIs) Stavudine, Lamivudine Lopinavir: ↔
Danish: Nukleosid/Nukleotid revers transkriptasehæmmere (NRTIs) Stavudin, lamivudin Lopinavir: ↔
English: (inhibition of CYP3A/efflux transporters)
Danish: (hæmning af CYP3A/effluks transportører)
English: Lopinavir is an inhibitor of the HIV-1 and HIV-2 proteases.
Danish: Lopinavir hæmmer hiv-1- og hiv-2-proteasen.
English: The risk of diarrhoea may be greater with once-daily dosing of Kaletra.
Danish: Risikoen for diarre kan være større hos patienter, som får Kaletra en gang dagligt.
English: The induced QRS interval prolongation from 6 ms to 9.5 ms with high dose lopinavir/ritonavir (800/200 mg twice daily) contributes to QT prolongation.
Danish: Den inducerede QRS-interval-forlængelse fra 6 ms til 9,5 ms med høj-dosis lopinavir/ritonavir (henholdsvis 800/200 mg to gange dagligt) medvirker til QT-forlængelse.
English: In HIV-infected patients with mild to moderate hepatic impairment, an increase of approximately 30% in lopinavir exposure has been observed but is not expected to be of clinical relevance (see section 5.2).
Danish: Hos hiv-inficerede patienter med mild til moderat svækket leverfunktion, er der set en stigning på omkring 30 % i lopinavir eksposition, men dette forventes ikke at have nogen klinisk relevans (se pkt.
English: Repeat-dose toxicity studies in rodents and dogs identified major target organs as the liver, kidney, thyroid, spleen and circulating red blood cells.
Danish: Toksicitetsstudier med gentagen indgift i gnavere og hunde har påvist de vigtigste målorganer som værende lever, nyre, thyreoidea, milten og cirkulerende røde blodceller.
English: Erectile dysfunction medicines (avanafil, vardenafil, sildenafil, tadalafil)
Danish: Lægemidler til behandling af rejsningsproblemer (avanafil, vardenafil, sildenafil, tadalafil)
English: Particular caution should be used when prescribing Kaletra in patients taking digoxin as the acute inhibitory effect of ritonavir on P-gp is expected to significantly increase digoxin levels.
Danish: Der bør udvises særlig forsigtighed ved ordination af Kaletra til patienter, som tager digoxin, da den akutte hæmmende effekt af ritonavir på Pgp forventes at få digoxinniveauet til at stige betydeligt.
English: The effects of Kaletra (in combination with other antiretroviral agents) on biological markers (plasma HIV RNA levels and CD4+ T-cell counts) have been investigated in controlled studies of Kaletra of 48 to 360 weeks duration.
Danish: Kaletras virkning (i kombination med andre antiretrovirale stoffer) på biologiske markører (plasmahiv-RNA-niveauer og CD4+ T-celletælling) er blevet vurderet i kontrollerede studier med Kaletra af 48 til 360 ugers varighed.
English: • ranolazine (used to treat chronic chest pain [angina]);
Danish: • ranolazin (bruges til behandling af kronisk smerte i brystet [angina]);
English: Isolates retained susceptibility to tipranavir with a median increase of IC50 in baseline and rebound isolates of 1.9- and 1.8-fold, respectively, compared to wild type virus.
Danish: Isolaterne bibeholdt følsomhed for tipranavir med en gennemsnitlig stigning af IC50 i henholdsvis baseline- og rebound-isolater på 1.9- og 1.8 gange, sammenlignet med vild-type virus.
English: Hepatitis including AST, ALT and GGT increases
Danish: Hepatit herunder stigning i AST, ALT og GGT
English: • Symptoms of dizziness, lightheadedness, fainting or sensation of abnormal heartbeats.
Danish: • Symptomer på svimmelhed, uklarhed, besvimelse eller fornemmelse af unormal hjerterytme.
English: • anticancer medicines (e.g. abemaciclib, afatinib, apalutamide, ceritinib, encorafenib, ibrutinib, venetoclax, most tyrosine kinases inhibitors such as dasatinib and nilotinib, also vincristine and vinblastine);
Danish: • medicin mod kræft (f.eks. abemaciclib, afatinib, apalutamid, ceritinib, encorafenib, ibrutinib, venetoclax, de fleste tyrosinkinasehæmmere sådan som dasatinib og nilotinib, også vincristin og vinblastin);
English: People taking Kaletra may still develop infections or other illnesses associated with HIV disease and AIDS.
Danish: Personer, der tager Kaletra, kan stadig udvikle infektioner eller sygdomme relateret til hiv-infektion eller AIDS.
English: • A history of liver problems as patients with a history of liver disease, including chronic hepatitis B or C are at increased risk of severe and potentially fatal liver side effects.
Danish: • Tidligere leverproblemer, da patienter, som tidligere har haft en leversygdom, herunder kronisk hepatitis B eller C, har en øget risiko for at få alvorlige og eventuelt dødbringende leverbivirkninger.
English: If the use of atorvastatin is considered strictly necessary, the lowest possible dose of atorvastatin should be administered with careful safety monitoring (see section 4.4).
Danish: Hvis anvendelse af atorvastatin vurderes at være strengt nødvendig, bør den lavest mulige dosis atorvastatin administreres med omhyggelig overvågning af sikkerheden (se pkt.
English: The following events have been reported in association with unintended overdoses in preterm neonates: complete atrioventricular block, cardiomyopathy, lactic acidosis, and acute renal failure.
Danish: Følgende hændelser er rapporteret i forbindelse med utilsigtet overdosering af præmature spædbørn: komplet atrioventrikulært blok, kardiomyopati, laktatacidose og akut nyresvigt.
English: Paediatric Use
Danish: Pædiatrisk anvendelse
English: Treatment emergent adverse events led to premature study discontinuation for 7% of subjects from Phase II-IV studies.
Danish: Bivirkninger under behandlingen medførte, at 7% af personerne i fase II-IVstudierne afsluttede studiet for tidligt.
English: (combinations of mechanisms including CYP3A inhibition)
Danish: (Kombination af mekanismer inklusive hæmning af CYP3A)
English: However, such a dose adjustment might be associated with ALT/AST elevations and with increase in gastrointestinal disorders.
Danish: Sådan en dosisjustering kan imidlertid være forbundet med ALT/AST-stigninger og med øgning i gastrointestinale lidelser.
English: • Joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement as some patients taking these medicines may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Danish: • Stivhed i led, ømhed og smerter (især i hofte, knæ og skulder) og indskrænket bevægelighed, da nogle patienter, som tager disse lægemidler, kan udvikle en knoglesygdom, der kaldes knoglenekrose (hvor knoglevævet dør som følge af nedsat blodtilførsel til knoglen).
English: Alpha1 adrenoreceptor antagonist Alfuzosin
Danish: Alfa1-antagonist: Alfuzosin
English: Adult patients who have not previously taken other antiviral medicines can also take Kaletra tablets once daily as an 800 mg/200 mg dose.
Danish: Voksne patienter, som ikke tidligere har taget anden antiviral medicin, kan også tage Kaletra tabletter en gang dagligt som en 800 mg/200 mg dosis.
English: Bepridil, Systemic Lidocaine, and Quinidine
Danish: Bepridil, systemisk lidocain og quinidin
English: Most tyrosine kinase inhibitors such as dasatinib and nilotinib, vincristine, vinblastine
Danish: De fleste tyrosinkinasehæmmere sådan som dasatinib og nilotinib, vincristin, vinblastin
English: Adult patients who have previously taken other antiviral medicines can take Kaletra tablets once daily as an 800 mg/200 mg dose if their doctor decides it is appropriate.
Danish: Voksne patienter, som tidligere har taget anden antiviral medicin kan tage Kaletra-tabletter en gang dagligt som en 800 mg/200 mg dosis, hvis deres læge beslutter, at det er hensigtsmæssigt.
English: This may result in lowered plasma concentrations and potential decrease of efficacy of co-administered medicinal products.
Danish: Det kan forårsage et fald i plasmakoncentrationer og dermed et potentielt fald i effekt af de lægemidler, der tages sammen med Kaletra.
English: For patients with renal impairment (CrCL < 30 ml/min) dose reduction of clarithromycin should be considered (see section 4.4).
Danish: Til patienter med nyreinsufficiens (kreatinin-clearence < 30 ml/min) bør nedsættelse af clarithromycin-dosis overvejes (se pkt.
English: After 48 weeks of treatment with Kaletra, efavirenz and nucleoside reverse transcriptase inhibitors, plasma HIV RNA ≤ 400 copies/ml was observed in 93% (25/27), 73% (11/15), and 25% (2/8) of patients with < 10-fold, 10 to 40-fold, and > 40-fold reduced susceptibility to lopinavir at baseline, respectively.
Danish: Efter 48 ugers behandling med Kaletra, efavirenz og nukleosid revers transkriptasehæmmere, blev plasma hiv-RNA ≤ 400 kopier/ml observeret hos 93 % (25/27), 73% (11/15), og 25 % (2/8) af patienterne med en følsomhed ved baseline, der var henholdsvis < 10 gange, 10-40 gange,, og > 40 gange nedsat overfor lopinavir.
English: Patients were administered emtricitabine 200 mg once daily and tenofovir DF 300 mg once daily (equivalent to 245 mg tenofovir disoproxil).
Danish: Patienterne fik emtricitabin 200 mg en gang dagligt og tenofovir DF 300 mg en gang dagligt (ækvivalent med 245 mg tenofovirdisoproxil).
English: Infants should be monitored closely for toxicity related to Kaletra oral solution including: hyperosmolality, with or without lactic acidosis, renal toxicity, central nervous system (CNS) depression (including stupor, coma, and apnea), seizures, hypotonia, cardiac arrhythmias and ECG changes, and hemolysis.
Danish: Spædbørn bør overvåges omhyggeligt for toksicitet relateret til Kaletra oral opløsning inklusive: hyperosmolalitet med eller uden laktatacidose, nyretoksicitet, centralnervesystems- (CNS-) depression (inklusive stupor, koma og apnø), krampeanfald, hypotoni, kardielle arytmier og ekg-forandringer samt hæmolyse.
English: • Once-daily administration of lopinavir/ritonavir is not recommended for pregnant women due to the lack of pharmacokinetic and clinical data.
Danish: • Det anbefales ikke at dosere lopinavir/ritonavir en gang dagligt til gravide, fordi der mangler farmakologisk og klinisk dokumentation herfor.
English: Analgesics Fentanyl
Danish: Analgetika Fentanyl
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING Oral Solution - Bottle label
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN INDRE EMBALLAGE Oral opløsning - flaskeetiket
English: Very common: may affect more than 1 in 10 people
Danish: Meget almindelige kan påvirke flere end 1 ud af 10 personer
English: Strong CYP3A4 inhibitors such as protease inhibitors may increase bedaquiline exposure which could potentially increase the risk of bedaquiline-related adverse reactions.
Danish: Potente CYP3A4-hæmmere, som f.eks. proteasehæmmere, kan øge bedaquilin-eksponeringen, hvilket potentielt kan øge risikoen for bedaquilin-relaterede bivirkninger.
English: Lopinavir binds to both alpha-1-acid glycoprotein (AAG) and albumin however, it has a higher affinity for AAG.
Danish: Lopinavir bindes både til alfa-1syre glucoprotein (AAG) og albumin, men har støre affinitet overfor AAG.
English: Patients with advanced HIV disease may be at risk of elevated triglycerides and pancreatitis.
Danish: Patienter med fremskredet hiv-infektion kan have forøget risiko for en stigning i triglycerider og pankreatitis.
English: A more pronounced effect on DM-6705 exposure may be observed during prolonged coadministration with lopinavir/ritonavir.
Danish: En mere udtalt virkning på DM6705 eksponering kan ses ved langvarig samtidig administration med lopinavir/ritonavir.
English: • amiodarone, dronedarone (used to treat abnormal heart beat);
Danish: • amiodaron, dronedaron (brugt til behandling af unormal hjerterytme);
English: No studies on the effects on the ability to drive and use machines have been performed.
Danish: Der er ikke udført studier af påvirkning af evnen til at føre bil eller betjene maskiner.
English: As compared to the BID regimen, the once-daily dosing is associated with a reduction in the Cmin/Ctrough values of approximately 50%.
Danish: Sammmenlignet med to gange dagligt regimet er dosering en gang dagligt forbundet med en reduktion i Cmin/Cthrough-værdierne på tilnærmelsesvis 50%.
English: For patients who have completed the ramp-up phase and are on a steady daily dose of venetoclax, reduce the venetoclax dose by at least 75% when used with strong CYP3A inhibitors (refer to the venetoclax SmPC for dosing instructions).
Danish: For patienter, der har afsluttet titreringsfasen og som er på en stabil dagligt dosis venetoclax, skal have venetoclax-dosis reduceret med mindst 75%, når det anvendes sammen med stærke CYP3A-hæmmere (se produktresuméet for venetoclax for doseringsanvisninger).
English: Patients with coexisting conditions
Danish: Patienter med særlige tilstande
English: Apalutamide is a moderate to strong CYP3A4 inducer and this may lead to a decreased exposure of lopinavir/ritonavir.
Danish: Apalutamid er en moderat til stærk CYP3A4-inducer og dette kan føre til nedsat eksponering for lopinavir/ritonavir.
English: After a 400/100 mg 14C-lopinavir/ritonavir dose, approximately 10.4 ± 2.3% and 82.6 ± 2.5% of an administered dose of 14C-lopinavir can be accounted for in urine and faeces, respectively.
Danish: Efter en dosis 400/100 mg 14C-lopinavir/ritonavir kan cirka 10,4 ± 2,3 % og 82,6 ± 2,5 % af den indgivne dosis genfindes henholdsvis i urin og fæces.
English: The dose of Kaletra may need adjusting.
Danish: Det kan være nødvendigt med justering af Kaletra-dosis.
English: Metabolic parameters Weight and levels of blood lipids and glucose may increase during antiretroviral therapy (see section
Danish: Metaboliske parametre Kropsvægt og niveauerne af lipid og glucose i blodet kan stige under antiretroviral behandling (se pkt.
English: One-hundred thirteen nelfinavir-treated patients and 74 lopinavir/ritonavir-treated patients had an HIV RNA above 400 copies/ml while on treatment from Week 24 through Week 96.
Danish: 113 nelfinavir-behandlede patienter og 74 lopinavir/ritonavir-behandlede patienter havde under behandling hiv-RNA over 400 kopier/ml fra uge 24 til og med uge 96.
English: Methadone: ↓
Danish: Methadon: ↓
English: The 5 bottle pack also contains five 5 ml syringes with 0.1 ml graduations.
Danish: Pakningen med 5 flasker indeholder også fem 5 ml sprøjter med 0,1 ml inddelinger.
English: Increased creatine phosphokinase (CPK), myalgia, myositis, and rarely, rhabdomyolysis have been reported with protease inhibitors, particularly in combination with nucleoside reverse transcriptase inhibitors.
Danish: Der er rapporteret om øget kreatinphosphokinase (CPK), myalgi, myositis og sjældne tilfælde af rabdomyolyse med proteasehæmmere, særligt i kombination med nukleosid revers transkriptase hæmmere.
English: SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF APPROPRIATE
Danish: EVENTUELLE SÆRLIGE FORHOLDSREGLER VED BORTSKAFFELSE AF IKKE ANVENDT LÆGEMIDDEL ELLER AFFALD HERAF
English: − This medicine has been prescribed for you or your child only.
Danish: - Lægen har kun ordineret Kaletra til dig eller dit barn.
English: Valproate: ↓
Danish: Valproat: ↓
English: • midazolam taken orally (taken by mouth), triazolam (used to relieve anxiety and/or trouble sleeping);
Danish: • midazolam, når det tages oralt (gennem munden)eller triazolam (bruges til at lindre angst og/eller afhjælpe søvnbesvær);
English: It is important to note that cases of pancreatitis have been reported in patients receiving Kaletra, including those who developed hypertriglyceridaemia.
Danish: Det er vigtigt at bemærke, at tilfælde af pankreatitis er blevet rapporteret hos patienter, der fik Kaletra, deriblandt patienter der udviklede hypertriglyceridæmi.
English: In vitro selection of resistance
Danish: Bedømmelse af In-vitro resistens
English: 3 tablets (300/75 mg)
Danish: 3 tabletter (300/75 mg)
English: • HIV CCR5-antagonist (e.g. maraviroc);
Danish: • hiv-CCR5-antagonister (f.eks. maraviroc);
English: To enhance bioavailability and minimise variability Kaletra is to be taken with food.
Danish: For at øge biotilgængeligheden og mindske udsving anbefales det at indtage Kaletra sammen med føde.
English: • HIV-1 integrase inhibitor (e.g. raltegravir);
Danish: • hiv-1-integrase-hæmmer (f.eks. raltegravir);
English: Patients should be informed that nausea has been reported during treatment with Kaletra (see section 4.8).
Danish: Patienterne bør informers om, at der er rapporteret om kvalme ved behandling med Kaletra (se pkt 4.8).
English: Colchicine:
Danish: Colchicin:
English: Always take this medicine exactly as your doctor has told you.
Danish: Tag altid Kaletra nøjagtigt efter lægens anvisning.
English: • ergotamine, dihydroergotamine, ergonovine, methylergonovine (used to treat headaches);
Danish: • ergotamin, dihydroergotamin, ergonovin og methylergonovin (brugt til behandling af migræne);
English: Kaletra oral solution is contraindicated in children below the age of 14 days, pregnant women, patients with hepatic or renal failure and patients treated with disulfiram or metronidazole due to the potential risk of toxicity from the excipient propylene glycol (see section 4.4).
Danish: Kaletra oral opløsning er kontraindiceret til børn under 14 dage gamle, gravide kvinder, patienter med lever- eller nyresvigt og patienter behandlet med disulfiram eller metronidazol på grund af den potentielle risiko for toxicitet fra hjælpestoffet propylenglycol (se pkt.
English: Myalgia, musculoskeletal pain including arthralgia and back pain, muscle disorders such as weakness and spasms
Danish: Myalgi, muskuloskeletale smerter inklusive artralgi og rygsmerter, muskellidelser så som svaghed og spasmer
English: This may cause nausea, vomiting, colic, severe purgation at high doses.
Danish: Det kan medføre kvalme, opkastning, kolik, effekt som et kraftigt afføringsmiddel ved høje doser.
English: For volumes greater than 2 ml.
Danish: Til voluminer større end 2 ml.
English: Lopinavir AUC over a 12 hour dosing interval averaged 113.2 ± 60.5 µg•h/ml.
Danish: Lopinavir AUC over et 12 timers doseringsinterval var i gennemsnit 113,2 ± 60,5 µg•h/ml.
English: For larger volumes an alternative pack is available.
Danish: En alternativ pakningsstørelse er tilgænglig til større voluminer.
English: (inhibition of CYP3A enzymes)
Danish: (hæmning af CYP3A-enzymer)
English: If the benefit outweighs the risk, co-administration of bedaquiline with Kaletra must be done with caution.
Danish: Hvis fordelen opvejer risikoen, skal samtidig administration af bedaquilin og Kaletra foretages med forsigtighed.
English: Furthermore, rare increases in PR interval have been reported during Kaletra therapy (see section 4.4).
Danish: Derudover er der i sjældne tilfælde blevet rapporteret forlænget PR-interval under Kaletra behandling (se pkt.
English: Ethinyl Oestradiol: ↓
Danish: Ethinylestradiol: ↓
English: Indeed, Kaletra could increase concentrations of the co-administered medicinal products and this may result in an increase of their associated cardiac adverse reactions.
Danish: Kaletra kan øge koncentrationerne af lægemidler, der anvendes samtidig, og dette kan resultere i en stigning i disses relaterede kardiale bivirkninger.
English: The combination of Kaletra with atorvastatin is not recommended.
Danish: Kombinationen af Kaletra med atorvastatin anbefales ikke.
English: Co-administration of delamanid with a strong inhibitor of CYP3A (as lopinavir/ritonavir) may increase exposure to delamanid metabolite, which has been associated with QTc prolongation.
Danish: Samtidig administration af delamanid og en potent CYP3A-hæmmer (som lopinavir/ritonavir) kan øge eksponeringen for delamanidmetabolitten, hvilket er sat i forbindelse med QTc-forlængelse.
English: Antifungals Ketoconazole and Itraconazole
Danish: Antimykotika Ketoconazol og itraconazol
English: • fatty deposits in the liver, enlarged liver;
Danish: • fedtaflejringer i leveren, forstørret lever;
English: Pimozide
Danish: Pimozid
English: The dose of maraviroc should be decreased to 150 mg twice daily during co-administration with Kaletra 400/100 mg twice daily.
Danish: Maraviroc-dosis bør nedsættes til 150 mg to gange dagligt ved samtidig administration af Kaletra 400/100 mg to gange dagligt.
English: Tell your doctor if you or your child have/had
Danish: Fortæl det til lægen, hvis du eller dit barn har eller har haft
English: The 2 bottle pack also contains two 2 ml syringes with 0.1 ml graduations.
Danish: Pakningen med 2 flasker indeholder også to 2 ml sprøjter med 0,1 ml inddelinger.
English: The steady state pharmacokinetic parameters of lopinavir in HIV-infected patients with mild to moderate hepatic impairment were compared with those of HIV-infected patients with normal hepatic function in a multiple dose study with lopinavir/ritonavir 400/100 mg twice daily.
Danish: Steady state farmakokinetiske parametre for lopinavir hos hiv-inficerede patienter med mild til moderet svækket leverfunktion blev sammelignet med de hiv-inficerede patienter med normal leverfunktion i et multidosis studie med lopinavir/ritonavir 400/100 mg to gange dagligt.