FrancophonIA/ELRC3.0 huggingface dataset:
English: At entry, median (range) HIV-1 RNA was 6.0 (4.7-7.2) log10 copies/ml and median (range) CD4+T-cell percentage was
Danish: Ved start var den interkvartile spændvidde hiv-1 RNA 6,0 (4,7-7,2) log10 kopier/ml og median CD4+T-cell procenten var 41 (16-59).
English: Anticancer agents Abemaciclib
Danish: Cytostatika Abemaciclib
English: • nausea;
Danish: • kvalme
English: Caution should be exercised in administering Kaletra with bosentan.
Danish: Der bør udvises forsigtighed ved samtidig administration af Kaletra og bosentan.
English: Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported; however, the reported time to onset is more variable and can occur many months after initiation of treatment (see section 4.4).
Danish: Den rapporterede tid til reaktionen indtræder er dog mere variabel, og reaktionen kan forekomme flere måneder efter påbegyndelse af behandlingen (se pkt.
English: Kaletra 100 mg/25 mg tablets
Danish: Kaletra 100mg/25mg tabletter
English: Kaletra tablets are administered orally and must be swallowed whole and not chewed, broken or crushed.
Danish: Kaletra-tabletter indgives oralt og skal synkes hele og ikke tygges, deles eller knuses.
English: (relative to indinavir 800 mg TID alone)
Danish: (I forhold til 800 mg tre gange dagligt alene)
English: Kaletra is indicated in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infected adults, adolescents and children above the age of 2 years.
Danish: Kaletra er indiceret til behandling af humant immundefektvirus (hiv)-1-smittede voksne, unge og børn over 2 år i kombination med andre antiretrovirale stoffer.
English: Kaletra contains lopinavir and ritonavir, both of which are inhibitors of the P450 isoform CYP3A.
Danish: Kaletra indeholder lopinavir og ritonavir, der begge hæmmer P-450-isoformen CYP3A.
English: Between week 24 and 48, patients randomised to a dose of 400/100 mg were converted to a dose of 533/133 mg.
Danish: Mellem uge 24 og 48 blev patienter som var randomiseret til dosen 400/100 mg ændret til en dosis på 533/133 mg. Mediant CD4-celletal ved baseline var 220 celler/mm3 (interval 13 til 1030 celler/mm3).
English: Antiretroviral Agents
Danish: Antiretrovirale Stoffer
English: Increased plasma concentrations of fusidic acid.
Danish: Forhøjede plasmakoncentrationer af fusidinsyre.
English: Kaletra 200 mg/50 mg film-coated tablets lopinavir/ritonavir
Danish: Kaletra 200 mg/50 mg filmovertrukne tabletter lopinavir/ritonavir
English: Due to the risk of QTc prolongation associated with DM-6705, if co-administration of delamanid with Kaletra is considered necessary, very frequent ECG monitoring throughout the full delamanid treatment period is recommended (see section 4.4 and refer to the delamanid SmPC).
Danish: Hvis samtidig administration af delamanid og Kaletra er nødvendigt, anbefales meget hyppig EKG-monitorering i hele behandlingsperioden med delamanid, da DM-6705 er forbundet med risiko for forlænget QTc (se pkt.
English: Kaletra 200 mg/50 mg film-coated tablets:
Danish: Kaletra 200 mg/50 mg filmovertrukne tabletter:
English: • anticoagulants (e.g. warfarin, rivaroxaban, vorapaxar);
Danish: • blodfortyndende lægemidler (f.eks. warfarin, rivaroxaban, vorapaxar);
English: The effect on DAAs and lopinavir was similar to that observed when lopinavir/ritonavir 400/100 mg BID was administered (see section 4.3).
Danish: Effekten af direkte virkende antivirale midler og lopinavir var sammenlignelig med det, som blev observeret ved administration af lopinavir/ritonavir 400/100 mg 2 gange dagligt (se pkt.
English: Study M98-863 was a randomised, double-blind trial of 653 antiretroviral treatment naïve patients investigating Kaletra (400/100 mg twice daily) compared to nelfinavir (750 mg three times daily) plus stavudine and lamivudine.
Danish: Studie M98-863 var en randomiseret, dobbeltblind afprøvning af Kaletra (400/100 mg to gange dagligt) hos 653 antiretroviral-naive patienter sammenlignet med nelfinavir (750 mg tre gange dagligt) og alle patienter fik samtidig stavudin og lamivudin.
English: Ombitasvir/paritaprevir/ritonavir with or without dasabuvir
Danish: Ombitasvir/paritaprevir/ritonavir med eller uden dasabuvir
English: Lopinavir/ritonavir medicinal product level decreased
Danish: Nedsat koncentration af lopinavir/ritonavir
English: • mouth sores or ulcerations, inflammation of the stomach and intestine;
Danish: • sår i munden, betændelse i maven og tarmen;
English: Kaletra must not be administered once daily in combination with efavirenz.
Danish: Kaletra må ikke indgives en gang dagligt i kombination med efavirenz.
English: Tablet contents:
Danish: Tabletovertræk:
English: Uncommon Rhabdomyolysis, osteonecrosis
Danish: Ikke almindelig Rabdomyolyse, osteonekrose
English: • If the ‘ml' mark on the collar is more than the prescribed dose, push the plunger to the prescribed dose.
Danish: • Hvis ”ml” markeringen på kraven er højere end den ordinerede dosis, tryk stemplet ind til den ordinerede dosis.
English: (see section 4.5); - riociguat is not recommended (see section 4.5); - vorapaxar is not recommended (see section 4.5); - fusidic acid in osteo-articular infections is not recommended (see section 4.5); - salmeterol is not recommended (see section 4.5); - rivaroxaban is not recommended (see section 4.5).
Danish: 4.5); - riociguat anbefales ikke (se pkt.
English: Kaletra is also supplied as 100 mg/25 mg film-coated tablets.
Danish: Kaletra fås også som 100/25 mg filmovertrukne tabletter.
English: Concomitant administration of Kaletra and astemizole and terfenadine is contraindicated as it may increase the risk of serious arrhythmias from these agents (see section 4.3).
Danish: Samtidig administration af Kaletra, astemizol og terfenadin er kontraindiceret, da riskoen for alvorlige arytmier forårsaget af disse lægemidler kan øges (se pkt.
English: Kaletra must not be administered once daily in combination with nevirapine.
Danish: Kaletra må ikke indgives en gang dagligt i kombination med nevirapin.
English: Etravirine (Lopinavir/ritonavir tablet 400/100 mg BID)
Danish: Etravirin (Lopinavir/ritonavir tablet 400/100 mg to gange dagligt)
English: • hair loss;
Danish: • hårtab;
English: Kaletra film-coated tablets are pale yellow debossed with [Abbott logo] and “KC”.
Danish: Kaletra filmovertrukne tabletter er svagt gule med påtrykt [Abbott-logo] og ”KC”.
English: The concomitant administration with quetiapine is contraindicated (see section
Danish: Administration sammen med quetiapin er kontraindiceret (se pkt.
English: − If you notice you miss a dose within 12 hours of your normal dosing time, take your missed dose as soon as possible, and then continue with your normal dose at the regular time as prescribed by your doctor.
Danish: - Hvis du opdager, at du har glemt en dosis inden for 12 timer fra det tidspunkt, du skulle have taget din dosis, skal du tage den glemte dosis snarest muligt og derefter fortsætte med at tage din normale dosis til sædvanlig tid, som foreskrevet af din læge.
English: The concomitant administration with alfuzosin is contraindicated (see section 4.5).
Danish: Samtidig administration af alfuzosin er kontraindiceret (se pkt.
English: • Use the 5 ml oral syringe provided to measure the dose.
Danish: • Brug den orale doseringssprøjte på 5 ml til at afmåle dosen.
English: Concomitant use of Kaletra with apalutamide is not recommended.
Danish: Kaletra bør ikke anvendes samtidig med apalutamid.
English: AUC: ↑ 5-fold
Danish: AUC: ↑ 5-gange
English: The use of avanafil with Kaletra is contraindicated (see section 4.3).
Danish: Anvendelse af avanafil med Kaletra er kontraindiceret (se pkt.
English: Ombitasvir/paritaprevir/rito navir + dasabuvir
Danish: Ombitasvir/paritaprevir/ri tonavir + dasabuvir
English: − If you notice you miss a dose within 6 hours of your normal dosing time, take your missed dose as soon as possible, and then continue with your normal dose at the regular time as prescribed by your doctor.
Danish: - Hvis du opdager, at du har glemt en dosis inden for 6 timer fra det tidspunkt, du skulle have taget din dosis, skal du tage den glemte dosis snarest muligt og derefter fortsætte med at tage din normale dosis til sædvanlig tid, som foreskrevet af din læge.
English: HIV RNA < 400 copies/ml
Danish: hiv-RNA < 400 kopier/ml
English: • Use the 2 ml oral syringe provided to measure the dose.
Danish: • Brug den orale doseringssprøjte på 2 ml til at afmåle dosen.
English: Mean baseline CD4+ T-cell count was 838 cells/mm3 and mean baseline plasma HIV-1 RNA was 4.7 log10 copies/ml.
Danish: Gennemsnitlig baseline CD4+ Tcelletal var 838 celler/mm3 og gennemsnitlig baseline plasma hiv-1-RNA var 4,7 log10 kopier/ml.
English: Kaletra film-coated tablets are yellow debossed with [Abbott logo] and “KA”.
Danish: Kaletra filmovertrukne tabletter er gule med påtrykt [Abbott-logo] og ”KA”.
English: Due to P-gp and/or CYP3A4 inhibition by ritonavir.
Danish: På grund af ritonavirs hæmning af P-gp og/eller CYP3A4.
English: Median baseline CD4 cell count was 349 cells/mm3 (range 72 to 807 cells/mm3) and median baseline plasma HIV-1 RNA was 4.0 log10 copies/ml (range 2.9 to 5.8 log10 copies/ml).
Danish: Mediant CD4-celletal ved baseline var 349 celler/mm3 (interval 72 til 807 celler/mm3) og median plasma-hiv-1-RNA ved baseline var 4,0 log10 kopier/ml (interval 2,9 til 5,8 log10 kopier/ml).
English: • you are allergic to lopinavir, ritonavir or any of the other ingredients of Kaletra (see section 6); • you have severe liver problems.
Danish: • hvis du er allergisk over for lopinavir, ritonavir eller et af de øvrige indholdsstoffer i Kaletra
English: If you or your child take more Kaletra than you should
Danish: Hvis du eller dit barn har taget for meget Kaletra
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING 200 mg/50 mg tablets - Carton of 1 bottle
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN INDRE EMBALLAGE 200 mg/50 mg tabletter - æske med 1 beholder
English: HIV RNA < 400 copies/ml*
Danish: hiv-RNA < 400 kopier/ml*
English: Ergot alkaloids Dihydroergotamine, ergonovine, ergotamine, methylergonovine
Danish: Sekalealkaloider Dihydroergotamin, ergonovin, ergotamin, methylergonovin
English: Fosamprenavir/ ritonavir (700/100 mg
Danish: Fosamprenavir/ ritonavir (700/100 mg to gange dagligt)
English: Antianginal
Danish: Antiarytmika
English: PARTICULARS TO APPEAR ON THE ON THE IMMEDIATE PACKAGING 200 mg/50 mg tablets - Bottle label
Danish: MÆRKNING DER SKAL VÆRE PÅ DEN INDRE EMBALLAGE BEHOLDERETIKET 200 mg/50 mg tabletter - beholderetiket
English: AUC: ↔ Cmin: ↓ 20%
Danish: Lopinavir : AUC: ↔ Cmin: ↓ 20%
English: − If you notice you miss a dose by more than 12 hours after your normal dosing time, do not take the missed dose.
Danish: - Hvis du opdager, at du har glemt en dosis 12 timer eller længere fra det tidspunkt, du skulle have taget dosis, skal du ikke tage den glemte dosis.
English: Use the 5 ml oral dosing syringe to prepare a dose.
Danish: Brug doseringssprøjten på 5 ml til at klargøre en dosis.
English: Film-coated tablet Yellow debossed with [Abbott logo] and “KA”.
Danish: Filmovertrukne tabletter Gule med præget [Abbott logo] og “KA”.
English: Each film-coated tablet contains 200 mg of lopinavir co-formulated with 50 mg of ritonavir as a pharmacokinetic enhancer.
Danish: Hver filmovertrukken tablet indeholder 200 mg lopinavir formuleret sammen med 50 mg ritonavir som farmakokinetisk forstærker.
English: − If you notice you miss a dose by more than 6 hours after your normal dosing time, do not take the missed dose.
Danish: - Hvis du opdager, at du har glemt en dosis 6 timer eller længere fra det tidspunkt, du skulle have taget din dosis, skal du ikke tage den glemte dosis.
English: Each film-coated tablet contains 100 mg of lopinavir co-formulated with 25 mg of ritonavir as a pharmacokinetic enhancer.
Danish: Hver filmovertrukken tablet indeholder 100 mg lopinavir formuleret sammen med 25 mg ritonavir som farmakokinetisk forstærker.
English: After each dose of Kaletra separate the plunger and the syringe.
Danish: Skil sprøjten og pumpestemplet ad efter hver dosis Kaletra.
English: Concomitant administration of Kaletra and cisapride is contraindicated as it may increase the risk of serious arrhythmias from this agent (see section 4.3).
Danish: Samtidig administration af Kaletra og cisaprid er kontraindiceret, da riskoen for alvorlige arytmier forårsaget af dette lægemiddel kan øges (se pkt.
English: Thereby, increasing the risk of serious arrhythmias from these agents (see section 4.5).
Danish: Derved øges risikoen for alvorlige arytmier forårsaget af disse lægemidler (se pkt.
English: Delamanid (100 mg BID)
Danish: Delamanid (100 mg 2 gange dagligt)
English: Kaletra 100 mg/25 mg film-coated tablets
Danish: Kaletra 100 mg/25 mg filmovertrukne tabletter
English: Volume of oral solution twice daily taken with food (80 mg lopinavir/20 mg ritonavir per ml)**
Danish: (80 mg lopinavir/20 mg ritonavir pr. ml)**
English: Patients with prior antiretroviral therapy
Danish: Antiretroviral-erfarne patienter
English: b. Tabulated list of adverse reactions
Danish: b. Bivirkninger i tabelform
English: Lopinavir/ritonavir 400/100 mg BID
Danish: Lopinavir/ritonavir 400/100 mg 2 gange dagligt
English: Although the etiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to combination antiretroviral therapy (CART).
Danish: Ætiologien anses dog for at være multifaktoriel (omfattende anvendelse af kortikosteroider, alkoholforbrug, svær immunosuppression, højere Body Mass Index (BMI)).
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer carton of multipacks of 120 (3 cartons of 40 film-coated 200 mg/50 mg film-coated tablets) - including the blue box
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE Ydre emballage af multipakning a 120 (3 æsker a 40 filmovertrukne tabletter) - inklusive blue box, Æske, som indeholder 120 200/50 mg filmovertrukne tabletter
English: Due to the risk of bedaquiline related adverse events, the combination of bedaquiline and Kaletra should be avoided.
Danish: Kombination af bedaquilin og Kaletra bør undgås på grund af risikoen for bedaquilinrelaterede bivirkninger.
English: The use of vardenafil with Kaletra is contraindicated (see section 4.3).
Danish: Anvendelse af vardenafil med Kaletra er kontraindiceret (se pkt.
English: Due to CYP3A inhibition by lopinavir/ritonavir, concentrations of lurasidone are expected to increase.
Danish: På grund af lopinavir/ritonavirs CYP3A-hæmning forventes koncentrationen af lurasidon at stige.
English: Increased plasma concentrations of avanafil (see sections 4.4 and 4.5).
Danish: Forhøjede plasmakoncentrationer af avanafil (se pkt.
English: Mean baseline CD4+ T-cell count was 216 cells/mm3 (range: 20 to 775 cells/mm3) and mean baseline plasma HIV-1 RNA was 5.0 log10 copies/ml (range: 1.7 to 7.0 log10 copies/ml).
Danish: Gennemsnitsbaseline CD4+ T-celletal var 216 celler/mm3 (interval: 20 til 775 celler/mm3) og gennemsnitsbaseline plasma-hiv-1-RNA var 5,0 log10 kopier/ml (interval: 1,7 til 7,0 log10 kopier/ml).
English: AUC: ↑ 13-fold Due to CYP3A inhibition by lopinavir/ritonavir.
Danish: AUC: ↑ 13-gange På grund af lopinavir/ritonavirs hæmning af CYP3A.
English: Given the pharmacokinetic interaction between Kaletra and tenofovir (see section 4.5), the results of this study might not be strictly extrapolable when other backbone regimens are used with Kaletra.
Danish: 4.5), er resulterne af dette studie måske ikke direkte ekstrapolerbare, når andre basis-regime bruges med Kaletra.
English: Each ml of Kaletra oral solution contains 80 mg of lopinavir and 20 mg of ritonavir.
Danish: Hver ml Kaletra oral opløsning indeholder 80 mg lopinavir og 20 mg ritonavir.
English: Interaction table
Danish: Interaktionstabel
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING 100 mg/ 25 mg tablets - Carton of 1 bottle
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE 100/25 mg tabletter- æske med 1 beholder
English: Use the 2 ml oral dosing syringe to prepare a dose.
Danish: Brug doseringssprøjten på 2 ml til at klargøre en dosis.
English: Studies in rats revealed that lopinavir is excreted in the milk.
Danish: Udskillelse af lopinavir i mælk er vist i rottestudier.
English: Rifabutin, 150 mg QD Rifabutin (parent drug and active 25-O-desacetyl metabolite):
Danish: Rifabutin (moderstof og den aktive 25-O-desacetyl metabolit): AUC: ↑5,7-gange Cmax: ↑3,5-gange
English: Antianginal Ranolazine
Danish: Midler mod angina pectoris Ranolazin
English: Voriconazole: Concentrations may be decreased.
Danish: Koncentrationerne kan være nedsat.
English: Concomitant administration of Kaletra and quetiapine is contraindicated as it may increase quetiapine-related toxicity.
Danish: Samtidig administration af Kaletra og pimozid er kontraindiceret, idet risikoen for alvorlige hæmatologiske stige.
English: Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported to occur in the setting of immune reconstitution; however, the reported time to onset is more variable and can occur many months after initiation of treatment.
Danish: Det er også rapporteret, at autoimmune sygdomme (såsom Graves sygdom og autoimmun hepatitis) kan forekomme i tilfælde af immunrekonstitution.
English: HIV RNA < 400 copies/ml (ITT)*
Danish: hiv-RNA < 400 kopier/ml (ITT)* hiv-RNA < 50 kopier/ml (ITT)*
English: Observed data
Danish: NC= Fejl Observerede data
English: AUC: ↑ 7.2-fold Cmax: ↑ 4.7-fold Cmin: ↑ 14.4-fold
Danish: Cmax: ↑ 4,7 gange Cmin: ↑ 14,4 gange
English: AUC: ↑ 13-fold
Danish: AUC: ↑ 13-gange
English: • If the ‘ml' mark on the black ‘O' ring is less than the prescribed dose, draw up more solution to the prescribed dose.
Danish: • Hvis ”ml" markering på den sorte ”O” ring er mindre end den ordinerede dosis, træk mere opløsning op til du rammer den ordinerede dosis.
English: Due to CYP3A inhibition by lopinavir/ritonavir, concentrations of ranolazine are expected to increase.
Danish: På grund af lopinavir/ritonavirs CYP3A-hæmning forventes koncentrationen af ranolazin at stige.
English: Kaletra tablets must be swallowed whole and not chewed, broken or crushed.
Danish: Kaletra tabletter skal synkes hele og ikke tygges, deles eller knuses.
English: Each ml of Kaletra contains 80 mg of lopinavir and 20 mg of ritonavir.
Danish: Hver ml af Kaletra indeholder 80 mg lopinavir og 20 mg ritonavir.
English: Kaletra 200 mg/50 mg film-coated tablets
Danish: Kaletra 200 mg/50 mg filmovertrukne tabletter
English: Overall failure rate combining the treatment differences across age strata, weighted by the precision of the estimate within each age stratum p=0.015 (Cohort I); p< 0.001 (Cohort II)
Danish: P=0,015 (kohorte I); P< 0,001 (kohorte II).
English: The adult dose of Kaletra tablets (400/100 mg twice daily) may be used in children 40 kg or greater or with a Body Surface Area (BSA)* greater than 1.4 m2. For children weighing less than 40 kg or with a BSA between 0.5 and 1.4 m2 and able to swallow tablets, refer to the dosing guideline tables below.
Danish: Dosis til voksne af Kaletra tabletter (400/100 mg to gange dagligt) kan anvendes til børn på 40 kg eller derover eller med en legemsverflade (BSA)* større end 1,4 m2 .
English: Film-coated tablet Pale yellow debossed with [Abbott logo] and “KC”.
Danish: Filmovertrukne tabletter Lysegule med præget [Abbott logo] og “KC”.
English: Mean baseline CD4+ T-cell count was 254 cells/mm3 (range: 4 to 952 cells/mm3) and mean baseline plasma HIV-1 RNA was 4.3 log10 copies/ml (range: 1.7 to 6.6 log10 copies/ml).
Danish: Gennemsnitsbaseline for CD4+ celletæling var 254 celler/mm3 (interval: 4 til 952 celler/mm3) og gennemsnitsbaseline for plasma hiv-1-RNA var 4,3 log10 kopier/ml (interval: 1,7 til 6,6 log10 kopier/ml).
English: PARTICULARS TO APPEAR ON THE ON THE IMMEDIATE PACKAGING 100 mg/25 mg tablets - bottle label
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN INDRE EMBALLAGE 100/25 mg tabletter- beholderetiket
English: Rash including maculopapular rash, dermatitis/rash including eczema and seborrheic dermatitis, night sweats, pruritus
Danish: Udslæt inklusive makulopapuløst udslæt, dermatit/udslæt inklusive eksem og seboreisk dermatit, nattesved, pruritus Ikke almindelig Alopeci, kapillarit, vaskulit Ikke kendt
English: Increased plasma concentrations of neratinib which may increase the potential for serious and/or life-threatening reactions (see section
Danish: Øgede plasmakoncentrationer af neratinib, som kan øge risikoen for alvorlige og livstruende reaktioner (se pkt.
English: − calcium channel antagonists (e.g. felodipine, nifedipine, nicardipine);
Danish: • hjertemedicin, herunder: digoxin; calciumantagonister (f.eks. felodipin, nifedipin, nicardipin);
English: Co-administration of encorafenib and Kaletra should be avoided.
Danish: Samtidig administration af encorafenib og Kaletra bør undgås.
English: B. PACKAGE LEAFLET
Danish: b. Bivirkninger i tableform
English: (Lopinavir/ritonavir 400/100 mg BID, multiple dose)
Danish: (Lopinavir/ritonavir 400/100 mg 2 gange dagligt fler-dosis)
English: Refer to colchicine prescribing information.
Danish: Se produktresuméet for colchicin.
English: Serum concentrations may be increased due to CYP3A inhibition by ritonavir.
Danish: Serumkoncentrationen kan øges på grund af ritonavirs hæmning af CYP3A.
English: It is not recommended to co-administer Kaletra and simeprevir.
Danish: Samtidig administration af Kaletra og simeprevir anbefales ikke
English: Serum concentrations of apalutamide may be increased due to CYP3A inhibition by lopinavir/ritonavir.
Danish: Serumkoncentrationen af apalutamid kan øges på grund af lopinavir/ritonavirs CYP3Ahæmning.
English: Mean baseline CD4+ T-cell count was 259 cells/mm3 (range: 2 to 949 cells/ mm3) and mean baseline plasma HIV-1 RNA was 4.9 log10 copies/ml (range: 2.6 to 6.8 log10 copies/ml).
Danish: Gennemsnitlig baseline CD4+ T-celletal var 259 celler/mm3 (interval: 2 til 949 celler/ mm3) og gennemsnitlig baseline plasma hiv-1-RNA var 4,9 log10 kopier/ml (interval: 2,6 til 6,8 log10 kopier/ml).
English: Due to CYP3A and P-gp inhibition by lopinavir/ritonavir.
Danish: På grund lopinavir/ritonavirs hæmning af CYP3A og P-gp.
English: Mean increase from baseline in CD4+ T-cell count (cells/mm3)
Danish: Gennemsnitlig stigning i CD4+ T-celletal (celler/mm3) fra baseline
English: Nevirapine, 200 mg BID
Danish: Nevirapin, 200 mg to gange dagligt
English: Herbal preparations containing St John's wort (Hypericum perforatum) due to the risk of decreased plasma concentrations and reduced clinical effects of lopinavir and ritonavir (see section 4.5).
Danish: Risiko for nedsat plasmakoncentration og klinisk effekt af lopinavir og ritonavir (se pkt.
English: Each ml contains: lopinavir 80 mg and ritonavir 20 mg.
Danish: Hver ml indeholder: 80 mg lopinavir og 20 mg ritonavir .
English: Due to CYP3A inhibition by lopinavir/ritonavir, concentrations of alfuzosin are expected to increase.
Danish: På grund af lopinavir/ritonavirs CYP3A-hæmning, forventes koncentrationen af alfuzosin at stige.
English: Thereby, increasing the risk of serious arrhythmias from this agent (see section 4.5).
Danish: Derved øges risikoen for alvorlige arytmier forårsaget af dette lægemiddel (se pkt.
English: Due to CYP3A inhibition by lopinavir/ritonavir, concentrations of lomitapide are expected to increase.
Danish: På grund af lopinavir/ritonavirs CYP3A-hæmning forventes koncentrationen af lomitapid at stige.
English: Increased plasma concentrations of lurasidone which may increase the potential for serious and/or lifethreatening reactions (see section 4.5).
Danish: Forhøjede plasmakoncentrationer af lurasidon som kan forøge risikoen for alvorlige og/eller livstruende reaktioner (se pkt.
English: Serum concentrations may be increased due to CYP3A and P-gp inhibition by lopinavir/ritonavir.
Danish: Serumkoncentrationen kan øges på grund af lopinavir/ritonavirs hæmning af CYP3A og P-gp.
English: Lipid-modifying agents HMG Co-A Reductase Inhibitors
Danish: HMG-CoA-reduktasehæmmere