FrancophonIA/ELRC3.0 huggingface dataset:
English: The following side effects were reported in patients with CTCL who were treated with the recommended initial dose of capsules.
Croatian: Sljedeće nuspojave bile su zabilježene u bolesnika s kožnim limfomom T stanica koji su bili liječeni preporučenom početnom dozom kapsula.
English: Nausea, diarrhoea, dry mouth, dry lips, loss of appetite, constipation, excess gas, abnormal liver function tests, vomiting.
Croatian: Mučnina, proljev, suha usta, suhe usne, gubitak apetita, zatvor, pretjerani plinovi, abnormalne jetrene probe, povraćanje.
English: Insomnia, dizziness, reduced skin sensation.
Croatian: Nesanica, omaglica, smanjen osjet u koži.
English: Decreases of haemoglobin should be managed according to current medical practice.
Croatian: Sniženja hemoglobina treba liječiti sukladno važećoj medicinskoj praksi.
English: It is unknown whether bexarotene is excreted in human milk.
Croatian: Nije poznato izlučuje li se beksaroten u majčino mlijeko u ljudi.
English: Associated Drug Co. Ltd Tel: + 356 2277 8000
Croatian: Ltd Tel: + 356 2277 8000
English: One capsule contains 75 mg of bexarotene.
Croatian: Jedna kapsula sadrži 75 mg beksarotena.
English: Hepatic insufficiency.
Croatian: Insuficijencija jetre.
English: Ecchymosis, petechia, abnormal white blood cells, thromboplastin decreased, abnormal erythrocytes, dehydration, increased gonadotrophic luteinizing hormone, weight loss, increased alkaline phosphatase, increased creatinine phosphokinase, lipase increased, hypercalcaemia, migraine, peripheral neuritis, paraesthesia, hypertonia, confusion, anxiety, emotional lability, somnolence, decreased libido, nervousness, night blindness, nystagmus, lacrimation disorder, tinnitus, taste perversion, chest pain, arrhythmia, peripheral vascular disorder, generalized oedema, haemoptysis, dyspnoea, increased cough, sinusitis, pharyngitis, dysphagia, mouth ulceration, oral moniliasis, stomatitis, dyspepsia, thirst, abnormal stools, eructation, vesicobullous rash, maculopapular rash, leg cramps, haematuria, flu syndrome, pelvic pain, and body odour.
Croatian: Novoopažene nuspojave ekhimoze, petehije, abnormalne bijele krvne stanice, sniženi tromboplastin, abnormalni eritrociti, dehidracija, povišen gonadotropni luteinizirajući hormon, gubitak na tjelesnoj težini, povišena alkalna fosfataza, povišena kreatinin fosfokinaza, povišena lipaza, hiperkalcemija, migrena, periferni neuritis, parestezija, hipertonija, konfuzija, anksioznost, emocionalna labilnost, somnolencija, smanjeni libido, nervoza, noćna sljepoća, nistagmus, poremećaj suzenja, tinitus, promjene osjeta okusa, bol u prsištu, aritmija, poremećaj perifernih krvnih žila, generalizirani edemi, hemoptiza, dispneja, pojačan kašalj, sinusitis, faringitis, disfagija, ulceracije u ustima, oralna monilijaza, stomatitis, dispepsija, žeđ, abnormalne stolice, podrigivanje, vezikulo-bulozni osip, makulopapularni osip, grčevi u nogama, hematurija, sindrom gripe, bol u zdjelici i neugodan tjelesni miris.
English: Bexarotene may potentially enhance the action of insulin, agents enhancing insulin secretion (e.g. sulfonylureas), or insulin-sensitisers (e.g. thiazolidinediones), resulting in hypoglycaemia (see section
Croatian: Beksaroten može potencijalno pojačati djelovanje inzulina, lijekova koji pojačavaju lučenje inzulina (npr. sulfonilureje) ili lijekova koji povećavaju osjetljivost na inzulin (npr. tiazolidindioni) što rezultira hipoglikemijom (vidjeti dio 4.4).
English: Dry skin, skin disorder, loss of hair, skin ulcer, acne, skin thickening, skin nodule, increased sweating.
Croatian: Suha koža, kožni poremećaj, gubitak kose, ranica na koži, akne, otvrdnuće kože, kožni čvorić, pojačano znojenje.
English: Caution should be exercised when administering bexarotene in patients using insulin, agents enhancing insulin secretion (e.g. sulfonylureas), or insulin-sensitisers (e.g. thiazolidinediones).
Croatian: Potreban je oprez kad se beksaroten primjenjuje u bolesnika koji uzimaju inzulin, sredstva za pojačavanje lučenja inzulina (npr. sulfonilureje) ili povećanje osjetljivosti na inzulin (npr. tiazolidindioni).
English: Butylated hydroxyanisole may cause irritation to the mucous membranes, therefore the capsules must be swallowed intact and not chewed.
Croatian: Butilhidroksianizol može prouzročiti nadraženost sluznica pa se stoga kapsule moraju progutati cijele i bez žvakanja.
English: Acute pancreatitis associated with elevations of fasting serum triglycerides has been reported in clinical studies.
Croatian: U kliničkim je ispitivanjima zabilježen akutni pankreatitis povezan s povišenim razinama triglicerida u serumu natašte.
English: Single observations of the following were also reported: bone marrow depression, decreased prothrombin, decreased gonadotrophic luteinizing hormone, increased amylase, hyponatraemia, hypokalaemia, hyperuricaemia, hypocholesterolaemia, hypolipaemia, hypomagnesaemia, abnormal gait, stupor, circumoral paraesthesia, abnormal thinking, eye pain, hypovolaemia, subdural haematoma, congestive heart failure, palpitation, epistaxis, vascular anomaly, vascular disorder, pallor, pneumonia, respiratory disorder, lung disorder, pleural disorder, cholecystitis, liver damage, jaundice, cholestatic jaundice, melaena, vomiting, laryngismus, tenesmus, rhinitis, increased appetite, gingivitis, herpes zoster, psoriasis, furunculosis, contact dermatitis, seborrhoea, lichenoid dermatitis, arthritis, joint disorder, urinary retention, impaired urination, polyuria, nocturia, impotence, urine abnormality, breast enlargement, carcinoma, photosensitivity reaction, face oedema, malaise, viral infection, enlarged abdomen.
Croatian: Jednokratna opažanja: bilo je zabilježeno i sljedeće: depresija koštane srži, snižen protrombin, snižen gonadotropni luteinizirajući hormon, povišena amilaza, hiponatremija, hipokalemija, hiperuricemija, hipokolesterolemija, hipolipemija, hipomagnezemija, abnormalni hod, stupor, cirkumoralna parestezija, abnormalno razmišljanje, bol u oku, hipovolemija, subduralni hematom, kongestivno zatajenje srca, palpitacije, epistaksa, krvožilna anomalija, krvožilni poremećaj, bljedoća, upala pluća, respiratorni poremećaj, poremećaj pluća, poremećaj pleure, kolecistitis, oštećenje jetre, žutica, kolestatska žutica, melena, povraćanje, laringizam, tenezmi, rinitis, pojačan apetit, gingivitis, herpes zoster, psorijaza, furunkuloza, kontaktni dermatitis,
English: Back pain, skin infection, fever, parasitic infection, abnormal laboratory test, disorder of mucous membrane, tumour.
Croatian: Bol u leđima, infekcija kože, vrućica, infekcija izazvana parazitima, abnormalni laboratorijski test, poremećaj sluznica, tumor.
English: • insulin, agents enhancing insulin secretion, or insulin-sensitisers (used against diabetes mellitus).
Croatian: • inzulin, lijekovi koji pojačavaju lučenje inzulina ili lijekovi koji povećavaju osjetljivost na inzulin (primjenjuju se kod šećerne bolesti).
English: Determination of white blood cell count with differential count should be obtained at baseline, weekly during the first month and then monthly thereafter.
Croatian: Broj bijelih krvnih stanica uz diferencijalnu krvnu sliku treba odrediti na početku, svakog tjedna tijekom prvog mjeseca liječenja, a potom jedanput mjesečno.
English: • dexamethasone (used for inflammatory conditions),
Croatian: • deksametazon (primjenjuje se kod upalnih stanja),
English: Changes in hair, herpes simplex, nail disorder, pustular rash, serous drainage, skin discoloration.
Croatian: Promjene kose, herpes simpleks, poremećaj nokta, osip u obliku gnojnih bubuljica, serozno vlaženje, promjena boje kože.
English: Capsule shell: gelatin sorbitol special-glycerin blend (glycerin, sorbitol, sorbitol anhydrides (1,4-sorbitan), mannitol and water) titanium dioxide (E171) printing ink (SDA 35A alcohol (ethanol & ethyl acetate), propylene glycol (E1520), iron oxide black (E172), polyvinyl acetate phthalate, purified water, isopropyl alcohol, macrogol 400, ammonium hydroxide 28%)
Croatian: Ovojnica kapsule: želatina smjesa sorbitola i glicerola (glicerol, sorbitol, sorbitol bezvodni (1,4-sorbitan), manitol i voda); titanijev dioksid (E171) tinta za označavanje (SDA 35A alkohol (etanol & etilacetat), propilenglikol (E1520), željezov oksid, crni (E172), poli(vinilacetat)ftalat, pročišćena voda, izopropilni alkohol, makrogol 400, amonijev hidroksid 28%)
English: Abnormal vision, blurred vision, inflammation of the eye lids, cataract, inflammation of the white part of the eye, lesion of the cornea of the eye, ear disorder, defect in field of vision.
Croatian: Abnormalni vid, zamagljen vid, upala vjeđa, katarakta, upala bjeloočnica, oštećenje rožnice oka, poremećaj uha, ispad vidnog polja.
English: United Kingdom Eisai Europe Ltd.
Croatian: United Kingdom Eisai Europe
English: Periodic eye exams may be needed if you experience visual difficulties while taking this medicine.
Croatian: Ako osjetite poteškoće s vidom dok uzimate ovaj lijek, možda će biti potrebno povremeno napraviti pregled očiju.
English: Uncontrolled thyroid disease.
Croatian: Nekontrolirana bolest štitne žlijezde.
English: Do not take more than 15,000 International Units of vitamin A supplements per day during treatment.
Croatian: Nemojte uzimati više od 15 000 međunarodnih jedinica (engl.
English: Determination of haemoglobin should be obtained at baseline, weekly during the first month and then monthly thereafter.
Croatian: Hemoglobin treba odrediti na početku, svakog tjedna tijekom prvog mjeseca, a potom jedanput mjesečno.
English: Vitamin A supplementation
Croatian: Nadoknada vitamina
English: The capsule shell consists of gelatin, sorbitol special-glycerine blend (glycerin, sorbitol, sorbitol anhydrides (1,4-sorbitan), mannitol and water), titanium dioxide (E171) and printing ink (SDA 35A alcohol (ethanol & ethyl acetate), propylene glycol (E1520), iron oxide black (E172), polyvinyl acetate phthalate, purified water, isopropyl alcohol, macrogol 400, ammonium hydroxide 28%).
Croatian: Ovojnica kapsule sastoji se od želatine, smjese sorbitola i glicerola (glicerol, sorbitol, sorbitol bezvodni (1,4-sorbitan), manitol i voda), titanijev dioksid (E171) i tinta za označavanje (SDA 35A alkohol (etanol & etilacetat), propilenglikol (E1520), željezov oksid crni (E172), poli(vinilacetat)ftalat, pročišćena voda, izopropilni alkohol, makrogol 400, amonijev hidroksid
English: - if you have a history of pancreatitis, have uncontrolled lipid (blood fats) elevations (high blood cholesterol or high blood triglycerides), have a condition known as hypervitaminosis A, have uncontrolled thyroid disease, have insufficient liver function or have an ongoing systemic infection.
Croatian: - ako ste trudni ili dojite ili ako možete zatrudnjeti, a ne koristite učinkovite mjere kontrole začeća. - ako ste bolovali od pankreatitisa, imate povišene lipide (masnoće u krvi) koje ne kontrolirate (visok kolesterol u krvi ili visoke trigliceride u krvi), imate stanje koje se zove hipervitaminoza A, nekontroliranu bolest štitne žlijezde, oslabljenu funkciju jetre ili prisutnu sistemsku infekciju.
English: Bexarotene should not be used in breast-feeding mothers.
Croatian: Beksaroten se ne smije primjenjivati u dojilja.
English: Because of the relationship of bexarotene to vitamin A, patients should be advised to limit vitamin A supplements to 15,000 IU/day to avoid potential additive toxic effects.
Croatian: Zbog odnosa beksarotena i vitamina A, bolesnicima treba savjetovati da ograniče nadoknadu vitamina
English: Dose modification guidelines The 300 mg/m 2/day dose level may be adjusted to 200 mg/m 2/day then to 100 mg/m 2/day, or temporarily suspended, if necessitated by toxicity.
Croatian: Možda će biti potrebno prilagoditi dozu od 300 mg/m 2 na dan na 200 mg/m 2 na dan, a zatim na
English: The uptake of bexarotene by organs or tissues has not been evaluated.
Croatian: Nije procijenjeno u kojoj mjeri organi i tkiva preuzimaju beksaroten.
English: However, an adverse effect of long-term bexarotene treatment on lens opacity formation in humans has not been excluded.
Croatian: Međutim, nastanak zamućenja leće kao nuspojave dugotrajnog liječenja beksarotenom u ljudi nije isključen.
English: How to store Targretin
Croatian: Kako čuvati Targretin
English: Mental health problems
Croatian: Psihičke tegobe
English: Each Targretin capsule contains 75 mg of the active substance bexarotene.
Croatian: Jedna Targretin kapsula sadrži 75 mg djelatne tvari beksarotena.
English: Ewopharma AG Sp. z o.o.
Croatian: Magyarország Ewopharma Hungary Ltd.
English: However, dizziness and visual difficulties have been reported in patients taking Targretin.
Croatian: Međutim, u bolesnika koji uzimaju Targretin zabilježeni su omaglica i poteškoće s vidom.
English: Vomiting Diarrhoea Nausea Anorexia Liver Function Tests Abnormal Cheilitis Dry Mouth Constipation Flatulence
Croatian: Poremećaji probavnog sustava povraćanje, proljev mučnina anoreksija abnormalni rezultati jetrenih pretraga, heilitis suha usta konstipacija, flatulencija pankreatitis zatajenje jetre, probavni poremećaj
English: Number of 75 mg Targretin capsules
Croatian: Broj Targretin kapsula od 75 mg
English: Magyarország Ewopharma Hungary Ltd. Tel: +36 1 200 46 50
Croatian: Ewopharma AG Sp. z o.o. Tel: +48 (22) 620 11 71
English: Under similar conditions, bexarotene concentrations were not affected by concomitant administration of atorvastatin or levothyroxine.
Croatian: Istodobna primjena atorvastatina ili levotiroksina nije utjecala na koncentracije beksarotena u sličnim uvjetima.
English: Pain Headache Asthaenia
Croatian: Srčani poremećaji tahikardija
English: Albuminuria Kidney Function Abnormal
Croatian: Poremećaji bubrega i mokraćnog sustava albuminurija abnormalna funkcija bubrega
English: Depression, depression aggravated, anxiety, and mood alterations have been reported in patients treated with systemic retinoids, including bexarotene.
Croatian: U bolesnika liječenih sistemskim retinoidima, uključujući beksaroten, prijavljeni su slučajevi depresije, pogoršanja depresije, anksioznosti i promjene raspoloženja.
English: Targretin 75 mg soft capsules
Croatian: Targretin 75 mg meke kapsule
English: Cataract Specified Amblyopia Visual Field Defect Corneal Lesion Abnormal Vision Blepharitis Conjunctivitis
Croatian: Poremećaji oka suhoća očiju, poremećaj očiju posebni oblik katarakte ambliopija ispad vidnog polja, lezija rožnice, abnormalni vid blefaritis, konjunktivitis
English: LFT elevations associated with the use of bexarotene have been reported.
Croatian: Zabilježeno je povišenje vrijednosti jetrenih proba povezano s primjenom beksarotena.
English: Leucopenia associated with bexarotene therapy has been reported in clinical studies.
Croatian: U kliničkim je ispitivanjima zabilježena leukopenija povezana s terapijom beksarotenom.
English: Gastrointestinal disorder, liver failure, inflammation of the pancreas.
Croatian: Probavni poremećaj, zatajenje jetre, upala gušterače.
English: Baseline LFTs should be obtained, and LFTs should be carefully monitored weekly during the first month and then monthly thereafter.
Croatian: Potrebno je dobiti rezultate jetrenih proba na početku, a zatim ih pratiti svakog tjedna tijekom prvog mjeseca liječenja, a potom jedanput mjesečno.
English: Anaemia associated with bexarotene therapy has been reported in clinical studies.
Croatian: U kliničkim je ispitivanjima zabilježena anemija povezana s terapijom beksarotenom.
English: To be swallowed whole.
Croatian: Kapsule treba progutati cijele.
English: Neoplasm Fever Cellulitis Infection Parasitic Mucous Membrane Disorder Back Pain Lab Test Abnormal adverse reactions noted with increased frequency when bexarotene was administered at a dose >300mg/m2/day.
Croatian: Opći poremećaji i reakcije na mjestu primjene bol, glavobolja, astenija alergijska reakcija, infekcija, zimice abdominalna bol, promijenjena razina hormona novotvorina, vrućica celulitis, parazitarna infekcija, poremećaj sluznica bol u leđima abnormalni laboratorijski nalazi nuspojave zabilježene s povećanom učestalošću kad se beksaroten primjenjivao u dozi >300 mg/m2 na dan. nuspojave zabilježene s povećanom učestalošću kad se beksaroten primjenjivao u dozi od 300 mg/m2 na dan u onkoloških bolesnika bez CTCL-a. nuspojave zabilježene s povećanom učestalošću kad se beksaroten primjenjivao u dozi >300 mg/m2 na dan (u usporedbi s primjenom doze od 300 mg/m2 na dan bolesnicima s CTCLom) u onkoloških bolesnika bez CTCL-a.
English: Pancreatitis Hepatic Failure Gastrointestinal Disorder
Croatian: Endokrini poremećaji hipotiroidizam poremećaj štitne žlijezde hipertiroidizam
English: Ear disorder
Croatian: Zamućenje leće
English: Ataxia Neuropathy Vertigo Hyperaesthesia Depression Agitation
Croatian: Poremećaji živčanog sustava omaglica, hipestezija, nesanica ataksija, neuropatija, vrtoglavica, hiperestezija, depresija agitiranost
English: Targretin 75 mg soft capsules Bexarotene
Croatian: TARGRETIN 75 mg meke kapsule beksaroten
English: TARGRETIN 75 mg soft capsules Bexarotene
Croatian: Targretin 75 mg meke kapsule beksaroten
English: Hyperthyroidism
Croatian: Metabolizam:
English: Furthermore, co-administration with CYP3A4 inducers such as rifampicin, phenytoin, dexamethasone or phenobarbital may theoretically cause a reduction in plasma bexarotene concentrations.
Croatian: Nadalje, istodobna primjena s induktorima CYP3A4 kao što su rifampicin, fenitoin,
English: Blood Dyscrasia Purpura Coagulation Disorder Coagulation Time Increased Anaemia Thrombocytopenia Thrombocythemia Eosinophilia Leukocytosis Lymphocytosis
Croatian: Poremećaji krvi i limfnog sustava leukopenija reakcija slična limfomu, limfadenopatija, hipokromna anemija krvna diskrazija, purpura, poremećaj koagulacije, produljeno vrijeme koagulacije anemija trombocitopenija trombocitemija, eozinofilija leukocitoza limfocitoza
English: Hyperlipidaemia has been identified as an effect associated with the use of bexarotene in clinical studies.
Croatian: U kliničkim se ispitivanjima prepoznala povezanost između hiperlipidemije i primjene beksarotena.
English: Ear and labyrinth disorders
Croatian: Interakcije s laboratorijskim pretragama
English: Weight Gain SGOT Increased SGPT Increased Lactic Dehydrogenase Increased Creatinine Increased Hypoproteinaemia
Croatian: Poremećaji metabolizma i prehrane hiperlipemija, hiperkolesterolemija povećanje tjelesne težine, povišen SGOT, povišen SGPT, povišena laktat dehidrogenaza, povišen kreatinin, hipoproteinemija ulozi, bilirubinemija povišen BUN sniženi lipoproteini visoke gustoće
English: Overactive thyroid.
Croatian: Pretjerano aktivna štitna žlijezda.
English: Dry Eyes Eye Disorder
Croatian: Poremećaji uha i labirinta gluhoća poremećaj uha
English: Joint aches, bone pain, muscle aches.
Croatian: Bolovi u zglobovima, bol u kostima, bolovi u mišićima.
English: 200 (2 x 100) tablets (multipack)
Croatian: 200 (2 x 100) tableta (višestruko pakiranje)
English: Strength Pharmaceutical Form
Croatian: Farmaceutski oblik Put primjene Unutarnje pakovanje Veličina pakiranja
English: The following regimes could be considered.
Croatian: Mogu se razmotriti sljedeći režimi.
English: ATC Code: J01XB01
Croatian: ATK oznaka: J01XB01
English: What [Product name] is and what it is used for
Croatian: Što je [naziv lijeka] i za što se koristi
English: The most appropriate time interval to the first maintenance dose has not been established.
Croatian: Nije ustanovljen najprikladniji vremenski interval do prve doze održavanja.
English: ≈ mg CBA
Croatian: IU ≈ mg CBA
English: The following dose adjustments are suggested as guidance.
Croatian: Sljedeće prilagodbe doze predlažu se kao smjernica.
English: Daily dose
Croatian: Dnevna doza
English: - medicines which can affect your nervous system.
Croatian: - lijekovi koji mogu utjecati na živčani sustav.
English: The following conversion table is prepared for information and the values must be considered nominal and approximate only.
Croatian: Sljedeća tablica za konverziju služi samo za informaciju pa se navedene vrijednosti moraju smatrati isključivo kao nominalne i približne.
English: Susceptible (S) Resistant (R) a
Croatian: rezistentan (R) a
English: Recommended dose range:
Croatian: Preporučen raspon doza:
English: Clinical experience with such doses is however extremely limited, and safety has not been established.
Croatian: Međutim, kliničko iskustvo s primjenom takvih doza je vrlo ograničeno, te sigurnost nije ustanovljena.
English: [Product name] is used when other antibiotics are not suitable.
Croatian: [Naziv lijeka] se primjenjuje kada drugi antibiotici nisu prikladni.
English: [Product name] can increase the effects of these medicines.
Croatian: [Naziv lijeka] može pojačati učinke tih lijekova.
English: Your doctor may decide to adjust the dose depending on your circumstances.
Croatian: Liječnik će možda odlučiti prilagoditi dozu sukladno Vašoj situaciji.
English: For children with a body weight above 40 kg, use of the dosing recommendation for adults should be considered.
Croatian: U djece tjelesne težine veće od 40 kg potrebno je razmotriti primjenu preporuka za doziranje u odraslih.
English: Protein binding is moderate and decreases at higher concentrations.
Croatian: Vezivanje za proteine je umjereno, a smanjuje se pri višim koncentracijama.
English: Note: The wording of this section should be replaced with the following wording:
Croatian: Napomena: Tekst u ovome dijelu potrebno je zamijeniti sljedećim:
English: The recommended doses in all subpopulations are equally based on limited data (clinical and pharmacokinetic/ pharmacodynamics data).
Croatian: Preporučene doze u svim subpopulacijama isto se tako temelje na ograničenim podacima (kliničkim i farmakokinetičkim/farmakodinamičkim podacima).
English: In some cases, your doctor may decide to give a higher daily dose of up to 12 million units.
Croatian: U nekim slučajevima liječnik može odlučiti primijeniti veću dnevnu dozu - do najviše 12 milijuna jedinica.
English: If you also take other inhaled medicines, your doctor will tell you which order to taken them in.
Croatian: Ako uzimate i druge lijekove koji se primjenjuju inhalacijom, liječnik će Vam reći kojim ih redoslijedom morate uzimati.
English: In patients with very poor renal function (creatinine clearance <30 ml/min), the extent of conversion could be as high as 60 to 70%.
Croatian: U bolesnika s vrlo slabom bubrežnom funkcijom (klirens kreatinina < 30 ml/min) opseg konverzije može dosegnuti čak 60 do 70%.
English: Based on limited data, the following dose is recommended in adults:
Croatian: Na temelju ograničenih podataka, u odraslih se bolesnika preporučuju sljedeće doze:
English: There are indications that pharmacokinetics in critically ill patients differ from those in patients with less severe physiological derangement and from those in healthy volunteers.
Croatian: Ima naznaka da se farmakokinetika u kritičnih bolesnika razlikuje od one u bolesnika s manje teškim fiziološkim poremećajima te one u zdravih dobrovoljaca.
English: Cross resistance between colistin (polymyxin E) and polymyxin B is expected.
Croatian: Očekuje se križna rezistencija između kolistina (polimiksina E) i polimiksina B.
English: In healthy subjects, 60% to 70% of CMS is excreted unchanged in the urine within 24 hours.
Croatian: U zdravih ispitanika se 60% do 70% KMN-a izlučuje u neizmjenjenom obliku kroz mokraću unutar 24 sata.
English: If other treatments are being taken, they should be taken in the order recommended by the physician.
Croatian: Ako se primjenjuju i druga liječenja, treba ih primjenjivati onim redoslijedom koji preporuči liječnik.
English: As necessary, expert advice should be sought when the local prevalence of resistance is such that the utility of the agent, in at least some types of infections, is questionable.
Croatian: Prema potrebi potrebno je potražiti savjet stručnjaka ako je lokalna prevalencija rezistencije takva da je korist lijeka, barem u nekim vrstama infekcija, upitna.
English: ≈ mass of CMS (mg)*
Croatian: ≈ masa KMN-a (mg)*
English: Discontinuation of therapy and the administration of specific treatment for Clostridium difficile should be considered.
Croatian: Potrebno je razmotriti obustavu liječenja i primjenu specifične terapije za Clostridium difficile.