FrancophonIA/ELRC3.0 huggingface dataset:
English: Given the primary CNS effects of olanzapine, caution should be used when it is taken in combination with other centrally acting medicines and alcohol.
Slovenian: Zaradi primarnih učinkov olanzapina na osrednje živčevje je potrebna previdnost, kadar se ga jemlje v kombinaciji z drugimi zdravili, ki delujejo na osrednje živčevje, in z alkoholom.
English: Potential for olanzapine to affect other medicinal products Olanzapine may antagonise the effects of direct and indirect dopamine agonists.
Slovenian: Zmožnost vpliva olanzapina na druga zdravila Olanzapin lahko zmanjša učinek neposrednih in posrednih dopaminskih agonistov.
English: Patients treated with any antipsychotic medicines, including Zalasta, should be observed for signs and symptoms of hyperglycaemia (such as polydipsia, polyuria, polyphagia, and weakness) and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control.
Slovenian: Bolnike, zdravljene s katerimkoli antipsihotikom, vključno z zdravilom Zalasta, moramo opazovati za znake in simptome hiperglikemije (kot so polidipsija, poliurija, polifagija in šibkost) ter redno spremljati bolnike s sladkorno boleznijo ali dejavniki tveganja za sladkorno bolezen glede poslabšanja nadzora glukoze.
English: Animal behavioural studies with olanzapine indicated 5HT, dopamine, and cholinergic antagonism, consistent with the receptor-binding profile.
Slovenian: Vedenjske raziskave na živalih so kazale na 5-HT, dopaminski in holinergični antagonizem v skladu s profilom vezave na receptorje.
English: In preclinical studies, olanzapine exhibited a range of receptor affinities (Ki < 100 nM) for serotonin 5 HT2A/2C, 5 HT3, 5 HT6; dopamine D1, D2, D3, D4, D5; cholinergic muscarinic receptors M1-M5; α1 adrenergic; and histamine H1 receptors.
Slovenian: V predkliničnih raziskavah z olanzapinom se je pokazal razpon afinitete do receptorjev (Ki; < 100 nM) za serotonin (5-HT2A/2C, 5-HT3, 5-HT6) in dopamin (D1, D2, D3, D4, D5), do holinergičnih muskarinskih receptorjev (M1-M5), adrenergičnih receptorjev α1 in histaminskih receptorjev H1.
English: Ventricular tachycardia/fibrillat ion, sudden death (see section 4.4)
Slovenian: Prekatna tahikardija/ fibrilacija, nenadna smrt (glejte poglavje 4.4)
English: Nevertheless, because human experience is limited, olanzapine should be used in pregnancy only if the potential benefit justifies the potential risk to the foetus.
Slovenian: Zaradi omejenih izkušenj je predpisovanje olanzapina med nosečnostjo upravičeno samo, če je predvidena korist za plod večja od morebitnega tveganja.
English: Because olanzapine may cause somnolence and dizziness, patients should be cautioned about operating machinery, including motor vehicles.
Slovenian: Olanzapin lahko povzroči zaspanost in omotičnost, zato je treba bolnike opozoriti, naj bodo previdni pri vožnji motornih vozil in pri upravljanju strojev.
English: In the same clinical trials, cerebrovascular adverse events (CVAE e.g., stroke, transient ischemic attack), including fatalities, were reported.
Slovenian: V istih kliničnih preizkušanjih so poročali o možganskožilnih neželenih dogodkih (npr. o možganski kapi, tranzitorni ishemični ataki), vključno s smrtnimi izidi.
English: Very common adverse reactions associated with the use of olanzapine in this patient group were abnormal gait and falls.
Slovenian: Zelo pogosta neželena učinka, povezana z jemanjem olanzapina, v tej skupini bolnikov sta bila neobičajna hoja in padci.
English: Olanzapine orodispersible tablet is bioequivalent to olanzapine tablets, with a similar rate and extent of absorption.
Slovenian: Orodisperzibilna tableta olanzapina je bioekvivalentna obloženim tabletam olanzapina ter ima podobno hitrost in obseg absorpcije.
English: The predominant pharmacologic activity is from the parent olanzapine.
Slovenian: Prevladujočo farmakološko aktivnost povzroča olanzapin.
English: In clinical studies, the average olanzapine exposure was approximately 27% higher in adolescents.
Slovenian: V kliničnih raziskavah so bili mladostniki povprečno za 27 % bolj izpostavljeni.
English: Olanzapine should be used cautiously in patients who have a history of seizures or are subject to factors which may lower the seizure threshold.
Slovenian: Olanzapin dajemo previdno bolnikom, ki so imeli v preteklosti epileptične napade ali so podvrženi dejavnikom, ki bi lahko znižali prag za epileptične napade.
English: However, as clinical experience with olanzapine in patients with concomitant illness is limited, caution is advised when prescribing for patients with prostatic hypertrophy, or paralytic ileus and related conditions.
Slovenian: Ker je kliničnih izkušenj z olanzapinom pri bolnikih s sočasnimi drugimi boleznimi malo, svetujemo previdnost pri predpisovanju zdravila bolnikom s hipertrofijo prostate ali s paralitičnim ileusom ter z njim povezanimi stanji.
English: In a study in breast-feeding, healthy women, olanzapine was excreted in breast milk.
Slovenian: V raziskavi na zdravih doječih ženskah so ugotovili, da se olanzapin izloča v materino mleko.
English: DRESS appears initially as flu-like symptoms with a rash on the face and then with an extended rash, high temperature, enlarged lymph nodes, increased levels of liver enzymes seen in blood tests and an increase in a type of white blood cell (eosinophilia).
Slovenian: Simptomi DRESS so ob nastopu sprva podobni simptomom gripe, z izpuščaji na obrazu, ki se nato razširijo drugam, povišano telesno temperaturo, povečanimi bezgavkami, povišano ravnijo jetrnih encimov ob krvnih preiskavah in povečanjem števila vrste belih krvnih celic (eozinofilija).
English: Olanzapine orodispersible tablets may be used as an alternative to olanzapine tablets.
Slovenian: Orodisperzibilne tablete olanzapina se lahko predpisujejo kot alternativa tabletam olanzapina.
English: Olanzapine administered with lithium or valproate resulted in increased levels ( 10%) of tremor, dry mouth, increased appetite, and weight gain.
Slovenian: Olanzapin, dan skupaj z litijem ali valproatom, je povzročil močnejše (≥ 10 %) tresenje, suha usta, povečan apetita in povečanje telesne mase.
English: Patients treated with any antipsychotic medicines, including Zalasta, should be monitored regularly for lipids in accordance with utilised antipsychotic guidelines, e.g. at baseline, 12 weeks after starting olanzapine treatment and every 5 years thereafter.
Slovenian: Bolnike, zdravljene s katerimkoli antipsihotikom, vključno z zdravilom Zalasta, moramo redno spremljati glede lipidov, v skladu z znanimi priporočili za antipsihotike, npr. na začetku, 12 tednov po začetku jemanja olanzapina in nato vsakih 5 let.
English: In patients with Parkinson's disease Zalasta may worsen the symptoms.
Slovenian: Pri bolnikih s Parkinsonovo boleznijo lahko zdravilo Zalasta poslabša simptome.
English: The magnitude of changes in fasting total cholesterol, LDL cholesterol, triglycerides, and prolactin (see sections 4.4 and 4.8) were greater in adolescents than in adults.
Slovenian: Vrednosti skupnega holesterola, merjenega na tešče, holesterola LDL in trigliceridov ter ravni prolaktina (gl. poglavji 4.4 in 4.8) so se bolj povečale pri mladostnikih kot pri odraslih.
English: ─ Very rarely, medicines of this type cause a combination of fever, faster breathing, sweating, muscle stiffness and drowsiness or sleepiness.
Slovenian: - Tovrstna zdravila zelo redko povzročijo kombinacijo zvišane telesne temperature, pospešenega dihanja, znojenja, mišične okorelosti, dremavosti ali zaspanosti.
English: In placebo-controlled clinical trials (6-12 weeks duration) of elderly patients (mean age 78 years) with dementia-related psychosis and/or disturbed behaviours, there was a 2-fold increase in the incidence of death in olanzapine-treated patients compared to patients treated with placebo (3.5% vs. 1.5%, respectively).
Slovenian: V kliničnih preizkušanjih, kontroliranih s placebom (ki so trajali 6 do 12 tednov), pri starejših bolnikih s psihozo, povezano z demenco, in/ali vedenjskimi motnjami (povprečna starost 78 let), je bilo 2-krat več smrtnih primerov med bolniki, zdravljenimi z olanzapinom, kot med bolniki, zdravljenimi s placebom (3,5 % v primerjavi z 1,5 %).
English: Olanzapine is well absorbed after oral administration, reaching peak plasma concentrations within 5 to 8 hours.
Slovenian: Olanzapin se po peroralnem dajanju dobro absorbira, maksimalno plazemsko koncentracijo pa doseže v 5 do 8 urah.
English: In a multinational, double-blind, comparative study of schizophrenia, schizoaffective, and related disorders which included 1,481 patients with varying degrees of associated depressive symptoms (baseline mean of 16.6 on the Montgomery-Asberg Depression Rating Scale), a prospective secondary analysis of baseline to endpoint mood score change demonstrated a statistically significant improvement (p=0.001) favouring olanzapine (-6.0) versus haloperidol (-3.1).
Slovenian: V dvojno slepi primerjalni raziskavi shizofrenije ter shizoafektivnih in sorodnih motenj, v kateri je sodelovalo več držav in skupaj 1481 bolnikov z različnimi stopnjami pridruženih depresivnih simptomov (izhodiščna srednja vrednost 16,6 na Montgomery-Asbergovi lestvici ocenjevanja depresije), je prospektivna sekundarna analiza spremembe od izhodiščne do končne ocene razpoloženja pokazala statistično značilno izboljšanje (p=0,001) v korist olanzapina (-6) v primerjavi s haloperidolom (-3,1).
English: In monkeys, single oral doses up to 100 mg/kg resulted in prostration and, at higher doses, semi-consciousness.
Slovenian: Pri opicah so enkratni peroralni odmerki do 100 mg/kg povzročili oslabelost, večji odmerki pa moteno zavest.
English: Age > 75 years and vascular/mixed type dementia were identified as risk factors for CVAE in association with olanzapine treatment.
Slovenian: Starost več kot 75 let in vaskularna/mešana demenca sta bili določeni kot dejavnika, ki prispevata k tveganju za možganskožilni dogodek, ki lahko nastopi v povezavi z zdravljenjem z olanzapinom.
English: While olanzapine demonstrated anticholinergic activity in vitro, experience during the clinical trials revealed a low incidence of related events.
Slovenian: Medtem ko je olanzapin v pogojih in vitro deloval antiholinergično, so klinična preizkušanja razkrila majhno incidenco s tem povezanih dogodkov.
English: You can also place the tablet in a full glass or cup of water.
Slovenian: Tableto lahko razpustite v kozarcu ali skodelici, polni vode.
English: Adolescents (ages 13 to 17 years): The pharmacokinetics of olanzapine are similar between adolescents and adults.
Slovenian: Farmakokinetika olanzapina je bila pri mladostnikih (starih od 13 do 17 let) podobna kot pri odraslih.
English: Growth parameters were decreased at high doses.
Slovenian: Po jemanju velikih odmerkov se je zmanjšala rast.
English: Risk factors that may predispose this patient population to increased mortality include age > 65 years, dysphagia, sedation, malnutrition and dehydration, pulmonary conditions (e.g., pneumonia, with or without aspiration), or concomitant use of benzodiazepines.
Slovenian: Dejavniki tveganja, ki pri tej skupini bolnikov lahko vplivajo na večjo umrljivost, so starost več kot 65 let, težave s požiranjem, sedacija, nezadostna prehrana ali dehidracija, pljučna obolenja (npr. pljučnica z aspiracijo ali brez nje) ali sočasno jemanje benzodiazepinov.
English: Neuroleptic Malignant Syndrome (NMS)
Slovenian: Nevroleptični maligni sindrom
English: In cases where hepatitis (including hepatocellular, cholestatic or mixed liver injury) has been diagnosed, olanzapine treatment should be discontinued.
Slovenian: Bolnike, pri katerih je ugotovljen hepatitis (vključno s hepatocelularno, holestatsko ali mešano jetrno okvaro), je treba prenehati zdraviti z olanzapinom.
English: In one clinical trial in patients with bipolar mania, valproate combination therapy with olanzapine resulted in an incidence of neutropenia of 4.1%; a potential contributing factor could be high plasma valproate levels.
Slovenian: V enem kliničnem preizkušanju na bolnikih z bipolarno motnjo je kombinirano zdravljenje z valproatom in olanzapinom povzročilo nevtropenije pri 4,1 % bolnikov; možen vzročni dejavnik so lahko povečane plazemske koncentracije valproata.
English: However the risk of tardive dyskinesia increases with long term exposure, and therefore if signs or symptoms of tardive dyskinesia appear in a patient on olanzapine, a dose reduction or discontinuation should be considered.
Slovenian: Ker pa tveganje za tardivne diskinezije narašča s trajanjem zdravljenja, je treba ob simptomih ali znakih tardivne diskinezije pri bolniku, ki jemlje olanzapin, razmisliti o zmanjšanju odmerka ali ukinitvi zdravila.
English: During antipsychotic treatment, improvement in the patient's clinical condition may take several days to some weeks.
Slovenian: Njihovo klinično stanje se lahko izboljša v nekaj dneh do nekaj tednih.
English: Effects on haematology parameters were found in each species, including dose-related reductions in circulating leukocytes in mice and non-specific reductions of circulating leukocytes in rats; however, no evidence of bone marrow cytotoxicity was found.
Slovenian: Pri vsaki preizkušani vrsti živali so odkrili učinke na hematološke parametre, tudi od velikosti odmerka odvisno zmanjšanje koncentracije levkocitov v krvi pri miših in nespecifično zmanjšanje koncentracije levkocitov v krvi pri podganah, vendar pa niso našli dokazov o citotoksičnosti za kostni mozeg.
English: The use of olanzapine in the treatment of dopamine agonist associated psychosis in patients with Parkinson's disease is not recommended.
Slovenian: Olanzapin ni priporočen za zdravljenje psihoze, povezane z dopaminskimi agonisti, pri bolnikih s Parkinsonovo boleznijo.
English: What you need to know before you take Zalasta
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Zalasta
English: As assessed by measured values from clinical trials in the Olanzapine Integrated Database.
Slovenian: Kot je bilo ocenjeno na podlagi meritev v kliničnih študijah v integrirani bazi podatkov za olanzapin.
English: Additional signs may include elevated creatine phosphokinase, myoglobinuria (rhabdomyolysis), and acute renal failure.
Slovenian: Dodatni znaki so lahko povečane vrednosti kreatinske fosfokinaze, mioglobinurija (rabdomioliza) in akutna ledvična odpoved.
English: Metabolism and nutrition disorders Very common: Weight gain
Slovenian: Presnovne in prehranske motnje zelo pogosti: povečanje telesne mase
English: The proportion of patients who had adverse, clinically significant changes in weight gain, glucose, total/LDL/HDL cholesterol or triglycerides increased over time.
Slovenian: Delež bolnikov s klinično značilnimi spremembami telesne mase, glukoze, skupnega holesterola ter holesterolov LDL in HDL ali trigliceridov se je sčasoma povečal.
English: Olanzapine is not indicated for use in the treatment of children and adolescents.
Slovenian: Olanzapin ni indiciran za zdravljenje otrok in mladostnikov.
English: Mean infant exposure (mg/kg) at steady state was estimated to be 1.8% of the maternal olanzapine dose (mg/kg).
Slovenian: Ocenili so, da dojenček od matere, ki je dolgotrajno jemala olanzapin, dobi 1,8 % materinega odmerka olanzapina (mg/kg).
English: Fluoxetine (a CYP2D6 inhibitor), single doses of antacid (aluminium, magnesium) or cimetidine have not been found to significantly affect the pharmacokinetics of olanzapine.
Slovenian: Za fluoksetin (zaviralec CYP2D6) in posamezne odmerke antacida (aluminij, magnezij) ali cimetidina niso ugotovili, da bi značilno vplivali na farmakokinetiko olanzapina.
English: Estrous cycles were affected at doses of 1.1 mg/kg (3 times the maximum human dose) and reproduction parameters were influenced in rats given 3 mg/kg (9 times the maximum human dose).
Slovenian: Odmerki po 1,1 mg/kg (tj. 3-kratni največji odmerek za človeka) so vplivali na estrusne cikle, odmerki po 3 mg/kg (tj. 9-kratni največji odmerek za človeka) pa so pri podganah vplivali na razmnoževanje.
English: Zalasta with alcohol
Slovenian: Zdravilo Zalasta skupaj z alkoholom
English: The frequency terms listed are defined as follows: Very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the data available).
Slovenian: Neželeni učinki so navedeni po padajoči resnosti, njihova pogostost pa je definirana z naslednjimi opisi: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
English: There were more smokers among subjects with cirrhosis (4/6; 67 %) than among subjects with no hepatic dysfunction (0/3;
Slovenian: Med osebami s cirozo (4/6, 67%) je bilo več kadilcev kot med osebami brez jetrne okvare (0/3, 0%).
English: Olanzapine does not inhibit the main CYP450 isoenzymes in vitro (e.g. 1A2, 2D6, 2C9, 2C19, 3A4).
Slovenian: Olanzapin v pogojih in vitro ne zavira delovanja glavnih izoencimov citokroma P450 (npr. 1A2, 2D6, 2C9, 2C19, 3A4).
English: Very common symptoms in overdose (> 10% incidence) include tachycardia, agitation/aggressiveness, dysarthria, various extrapyramidal symptoms, and reduced level of consciousness ranging from sedation to coma.
Slovenian: Zelo pogosti simptomi pri prevelikem odmerjanju (incidenca > 10 %) vključujejo tahikardijo, vznemirjenost/nasilnost, dizartrijo, različne ekstrapiramidne simptome in motnje zavesti v razponu od sedacije do kome.
English: Studies in patients aged 13-17 years showed various adverse reactions, including weight gain, changes in metabolic parameters and increases in prolactin levels (see sections 4.8 and 5.1).
Slovenian: V raziskavah na bolnikih, starih od 13 do 17 let, so ugotovili različne neželene učinke, vključno s povečanjem telesne mase, presnovnimi spremembami in zvišano ravnjo prolaktina (gl. poglavji 4.8 in 5.1).
English: In renally impaired patients (creatinine clearance < 10 ml/min) versus healthy subjects, there was no significant difference in mean elimination half-life (37.7 versus 32.4 hr) or clearance (21.2 versus 25.0 l/hr).
Slovenian: Pri bolnikih z okvarjenim ledvičnim delovanjem (kreatininski očistek < 10 ml/min) v primerjavi z zdravimi osebami ni bilo značilne razlike v srednjem razpolovnem času izločanja (37,7 v primerjavi z 32,4 ure) ali v očistku (21,2 v primerjavi s 25,0 l/h).
English: If you suffer from any of the following illnesses tell your doctor as soon as possible: ─ Stroke or “mini” stroke (temporary symptoms of stroke) ─ Parkinson's disease ─ Prostate problems ─ A blocked intestine (Paralytic ileus) ─ Liver or kidney disease ─ Blood disorders ─ Heart disease ─ Diabetes ─ Seizures ─ If you know that you may have salt depletion as a result of prolonged severe diarrhoea and vomiting (being sick) or usage of diuretics (water tablets)
Slovenian: Čim prej povejte svojemu zdravniku, če imate katero od spodaj naštetih bolezni: - možgansko kap ali "majhno" možgansko kap (prehodni znaki kapi) - Parkinsonovo bolezen - težave s prostato - zaporo črevesa (paralitični ileus) - obolenje jeter ali ledvic - bolezni krvi - srčno obolenje - sladkorno bolezen - krče - če veste, da imate morda pomanjkanje soli zaradi dolgotrajne hude driske in bruhanja ali uporabe diuretikov (tablet za odvajanje vode)
English: Patients gaining ≥ 7 %, ≥ 15 % and ≥ 25 % of their baseline body weight with long-term exposure (at least 48 weeks) were very common (64.4 %, 31.7 % and 12.3 % respectively).
Slovenian: Povečanje izhodiščne telesne mase za ≥ 7 %, ≥ 15 % in ≥ 25 % je bilo pri dolgotrajnem jemanju olanzapina (vsaj 48 tednov) zelo pogosto (v 64,4 %, 31,7 % in
English: Olanzapine was started at 2.5 mg/day and titrated to a maximum of 15 mg/day based on investigator judgement.
Slovenian: Začetni odmerek olanzapina je bil 2,5 mg na dan, nato pa so ga na podlagi presoje preiskovalca postopoma povečevali do največjega odmerka, ki je znašal 15 mg na dan.
English: For patients who have been receiving olanzapine for treatment of manic episode, continue therapy for preventing recurrence at the same dose.
Slovenian: Pri bolnikih, ki so jemali olanzapin za zdravljenje manične epizode, nadaljujte zdravljenje z enakim odmerkom olanzapina za preprečevanje ponovnega pojava bolezni.
English: Swallow the tablet with or without water.
Slovenian: Tableto lahko pogoltnete z vodo ali brez nje.
English: orodispersible tablet
Slovenian: orodisperzibilna tableta
English: Controlled efficacy data in adolescents (ages 13 to 17 years) are limited to short term studies in schizophrenia (6 weeks) and mania associated with bipolar I disorder (3 weeks), involving less than 200 adolescents.
Slovenian: Nadzorovani podatki o učinkovitosti zdravljenja manj kot dvesto mladostnikov (starih od 13 do 17 let) so omejeni na podatke iz kratkotrajnih študij olanzapina pri zdravljenju shizofrenije (6 tednov) in manije, povezane z bipolarno motnjo (3 tedni).
English: You should take your Zalasta tablets once a day following the advice of your doctor.
Slovenian: Zalasta jemljite enkrat na dan. Vedno upoštevajte zdravnikov nasvet.
English: It is important that you carry on taking Zalasta for as long as your doctor tells you.
Slovenian: Pomembno je, da zdravilo Zalasta jemljete tako dolgo, kot vam je naročil zdravnik.
English: During treatment with olanzapine in combination with lithium or divalproex, an increase of  7% from baseline body weight occurred in 17.4% of patients during acute treatment (up to 6 weeks).
Slovenian: Med zdravljenjem z olanzapinom v kombinaciji z litijem ali divalproeksom se je 17,4 % bolnikov med akutnim zdravljenjem (do 6 tednov) povečala telesna masa, in sicer za > 7 % od osnovne.
English: Patients who have taken more Zalasta than they should have experienced the following symptoms: rapid beating of the heart, agitation/aggressiveness, problems with speech, unusual movements (especially of the face or tongue) and reduced level of consciousness.
Slovenian: Če ste vzeli večji odmerek zdravila Zalasta, kot bi smeli Bolniki, ki so vzeli večji odmerek zdravila Zalasta, kot bi smeli, so imeli naslednje simptome: hitro bitje srca, vznemirjenost/nasilnost, težave pri govoru, nenavadne zgibke (posebno v mišicah obraza ali jezika) in zmanjšano stopnjo zavesti.
English: A lower starting dose (5 mg/day) is not routinely indicated but should be considered for those 65 and over when clinical factors warrant (see also section 4.4).
Slovenian: Z manjšim začetnim odmerkom (5 mg na dan) zdravite bolnike, stare več kot 65 let, kadar to opravičujejo klinični dejavniki (gl. tudi poglavje 4.4).
English: The following table lists the adverse reactions and laboratory investigations observed from spontaneous reporting and in clinical trials.
Slovenian: V naslednji tabeli so navedeni neželeni učinki, ki so jih navajali bolniki, in laboratorijske preiskave, ki so jih izvajali med kliničnimi preizkušanji.
English: Mean increases in fasting lipid values (total cholesterol, LDL cholesterol, and triglycerides) were greater in patients without evidence of lipid dysregulation at baseline.
Slovenian: Povprečno povečanje vrednosti lipidov na tešče (skupni holesterol, holesterol LDL in trigliceridi) je bilo večje pri bolnikih, pri katerih v izhodišču ni bila dokazana motnja v delovanju lipidov.
English: Dogs tolerated single oral doses up to 100 mg/kg without mortality.
Slovenian: Psi so prenesli enkratne peroralne odmerke do 100 mg/kg.