FrancophonIA/ELRC3.0 huggingface dataset:
English: In both studies, patients were randomised to receive either placebo, 5 mg/kg infliximab, or 10 mg/kg infliximab at weeks 0, 2, 6, 14, and 22, and in study 6 at weeks 30, 38, and 46.
Danish: I begge studier var patienterne randomiseret til at få enten placebo, 5 mg/kg infliximab eller 10 mg/kg infliximab i uge 0, 2, 6, 14 og 22, og i studie 6 i uge 30, 38 og 46.
English: In a developmental toxicity study conducted in mice using an analogous antibody that selectively inhibits the functional activity of mouse TNFα, there was no indication of maternal toxicity, embryotoxicity or teratogenicity (see section 5.3).
Danish: I et toksicitetsstudie vedrørende udvikling udført på mus med et analogt antistof, som selektivt hæmmer den funktionelle aktivitet af muse-TNFα, var der ingen tegn på maternel toksicitet, embryotoksicitet eller teratogenicitet (se pkt.
English: There have been post-marketing reports of worsening heart failure, with and without identifiable precipitating factors, in patients taking infliximab.
Danish: Efter markedsføring er der rapporteret tilfælde af forværret hjerteinsufficiens hos infliximab patienter, med eller uden identificerbare predisponerende faktorer.
English: * P-values represent each infliximab treatment group vs. AZA monotherapy.
Danish: (p < 0,001)* * P-værdier repræsenterer hver infliximab-behandlingsgruppe vs. AZA monoterapi.
English: The safety and efficacy of re-administration, other than every 6 to 8 weeks, has not been established (see sections 4.4 and 4.8).
Danish: Sikkerhed og effekt ved fornyet indgift, udover hver 6. til 8. uge, er ikke vist (se pkt.
English: In the first study, (study 8), which had a 3 month double-blind phase, 70 patients received either 5 mg/kg infliximab or placebo at weeks 0, 2, 6 (35 patients in each group).
Danish: I det første studie (studie 8), som havde en dobbelblind fase på 3 måneder, modtog 70 patienter enten 5 mg/kg infliximab eller placebo i uge 0, 2, 6 (35 patienter i hver gruppe).
English: In Phase III clinical studies, 18% of infliximabtreated patients compared with 5% of placebo-treated patients experienced an infusion-related reaction.
Danish: I fase III kliniske studier oplevede 18 % af de infliximab-behandlede patienter en infusionsrelateret reaktion sammenlignet med 5 % af de placebobehandlede patienter.
English: Median follow-up (wks)4
Danish: Antal patienter3 Medianopfølgning (uger)4
English: When reconstitution and dilution are performed under aseptic conditions, Zessly infusion solution can be used within 24 hours if stored at 2°C - 8°C.
Danish: Når rekonstitution og fortynding er udført under aseptiske forhold, kan Zessly infusionsvæske anvendes inden for 24 timer, hvis den opbevares ved 2°C - 8°C.
English: A total of 306 patients received 3 doses of infliximab 5 mg/kg at week 0, 2, and 6.
Danish: I alt 306 patienter fik 3 doser infliximab på 5 mg/kg i ugerne 0, 2 og 6.
English: The safety and efficacy of infliximab have not been studied in children with Crohn's disease below the age of 6 years.
Danish: Infliximabs sikkerhed og virkning hos børn under 6 år med Crohns sygdom er ikke klarlagt.
English: For more information about the safety of infliximab in elderly patients see sections 4.4 and 4.8.
Danish: 4.4 og 4.8 for mere information omkring sikkerhed ved brug af infliximab hos ældre patienter.
English: It is recommended that paediatric patients, if possible, be brought up to date with all vaccinations in agreement with current vaccination guidelines prior to initiating Zessly therapy.
Danish: Det anbefales, at pædiatriske patienter bliver vaccineret i overensstemmelse med gældende vaccinationsvejledninger, før Zesslybehandling påbegyndes, hvis dette er muligt.
English: Ankylosing spondylitis (Bechterew's disease)
Danish: Ankyloserende spondylitis (Bekhterevs sygdom)
English: Patients received three doses of either placebo or infliximab at weeks 0, 2, and 6.
Danish: Patienterne modtog tre doser af enten placebo eller infliximab i uge 0, 2 og 6.
English: Very common (may affect more than 1 in 10 people)
Danish: Meget almindelig: (kan forekomme hos flere end 1 ud af 10 personer)
English: The concurrent administration of live vaccines with Zessly is not recommended.
Danish: Samtidig administration af levende vacciner og Zessly frarådes.
English: Placebo + MTX 3 mg/kg
Danish: infliximab + MTX Placebo + MTX 3 mg/kg 6 mg/kg Kombineret
English: Neutropenia, leukopenia, anaemia, lymphadenopathy.
Danish: Neutropeni, leukopeni, anæmi, lymfadenopati.
English: Crohn's disease (Crohn's Disease Activity Index (CDAI) ≥ 220 ≤ 400) in a randomised, double blinded, placebo-controlled, dose-response study.
Danish: Effekten af en éndosis behandling med infliximab blev vurderet hos 108 patienter med aktiv Crohns sygdom (Crohn's Disease Activity Index (CDAI) ≥ 220 ≤ 400) i et randomiseret, dobbeltblindet, placebokontrolleret, dosis-virknings studie.
English: Signs include fever, cough, flu-like signs, feeling unwell, red or hot skin, wounds or dental problems.
Danish: Tegn inkludererfeber, hoste, influenzalignende symptomer, utilpashed, rød eller ophedet hud, sår eller problemer med tænderne.
English: Infliximab with or without AZA was assessed in a randomised, double-blind, active comparator study of 508 adult patients with moderate to severe Crohn's disease (CDAI ≥ 220 ≤ 450) who were naive to biologics and immunosuppressants and had a median disease duration of 2.3 years.
Danish: Infliximab med eller uden AZA blev vurderet i et randomiseret, dobbeltblind studie med aktiv komparator hos 508 voksne patienter med moderat til svær Crohns sygdom (CDAI ≥ 220 ≤ 450).
English: A population-based retrospective cohort study found an increased incidence of cervical cancer in women with rheumatoid arthritis treated with infliximab compared to biologics-naïve patients or the general population, including those over 60 years of age (see section 4.4).
Danish: I et populationsbaseret, retrospektivt kohortestudie sås en øget incidens af livmoderhalskræft hos kvinder med reumatoid arthritis, som var blevet behandlet med infliximab, sammenlignet med patienter, der var naive i forhold til biologiske lægemidler, eller befolkningen generelt, inklusive kvinder over 60 år (se pkt.
English: • Signs of an immune system disorder such as joint pain or a rash on cheeks or arms that is sensitive to the sun (lupus) or cough, shortness of breath, fever or skin rash (sarcoidosis)..
Danish: • Tegn på en sygdom i immunsystemet såsom ledsmerter, udslæt på kinder eller arme, som er følsomme over for solen (lupus) eller hoste, åndenød, feber eller hududslæt (sarkoidose).
English: Paediatric patients on infliximab may receive concurrent vaccinations, except for live vaccines (see sections 4.5 and
Danish: Pædiatriske patienter, der får infliximab, kan få vaccinationer samtidigt, med undtagelse af levende vacciner (se pkt.
English: b n = 292. c Analysis was based on subjects with nail psoriasis at baseline (81.8% of subjects).
Danish: Analysen var baseret på patienter med neglepsoriasis ved baseline (81,8 % af patienterne).
English: Carriers of HBV who require treatment with Zessly should be closely monitored for signs and symptoms of active HBV infection throughout therapy and for several months following termination of therapy.
Danish: Hos patienter med positiv test for HBV-infektion, anbefales det at rådføre sig med en læge med erfaring i behandling af hepatitis B. Bærere af HBV, hvor behandling med Zessly er nødvendig, skal følges nøje under behandlingen og i adskillige måneder efter afslutning af behandlingen for at registere tegn og symptomer på aktiv HBV-infektion.
English: Vertigo, dizziness, hypoesthesia, paraesthesia.
Danish: Vertigo, svimmelhed, hypæstesi, paræstesi.
English: • Signs of a heart problem such as chest discomfort or pain, arm pain, stomach pain, shortness of breath, anxiety, light-headedness, dizziness, fainting, sweating, nausea (feeling seek), vomiting, fluttering or pounding in your chest, a fast or a slow heartbeat, and swelling of your feet.
Danish: • Tegn på hjerteproblemer såsom ubehag i brystkassen eller brystsmerter, armsmerter, mavesmerter, åndenød, angst, ørhed, svimmelhed, besvimelse, svedtendens, kvalme (utilpashed), opkastning, skælven eller banken i brystet, hurtigt eller langsomt hjerteslag og hævede fødder.
English: The safety and efficacy of re-administration, other than every 8 weeks, has not been established (see sections 4.4 and 4.8).
Danish: Sikkerhed og effekt ved fornyet indgift, udover hver 8. uge, er ikke vist (se pkt.
English: Rare (may affect up to 1 in 1,000 people)
Danish: Sjælden: (kan forekomme hos op til 1 ud af 1.000 personer)
English: Zessly is indicated for treatment of moderately to severely active ulcerative colitis in adult patients who have had an inadequate response to conventional therapy including corticosteroids and 6mercaptopurine (6-MP) or azathioprine (AZA), or who are intolerant to or have medical contraindications for such therapies.
Danish: Zessly er indiceret til behandling af moderat til svær, aktiv colitis ulcerosa hos voksne patienter, som har haft utilstrækkelig respons af konventionel behandling inklusive kortikosteroider og 6-mercaptopurin (6-MP) eller azathioprin (AZA), eller som er intolerante over for eller har kliniske kontraindikationer for sådanne behandlinger.
English: Excipients: Disodium succinate hexahydrate, succinic acid, sucrose, polysorbate 80.
Danish: Hjælpestoffer: Dinatriumsuccinathexahydrat, ravsyre, saccharose, polysorbat 80.
English: 5 mg/kg
Danish: 5 mg/kg 10 mg/kg
English: Thirty two (32) evaluable paediatric patients crossed over (9 subjects in the q8 weeks and 23 subjects in the q12 weeks maintenance groups).
Danish: Hos 32 evaluérbare patienter blev doseringen ændret (9 personer i 8. ugers gruppen og 23 i 12. ugers gruppen).
English: There have been reports of pancytopenia, leukopenia, neutropenia, and thrombocytopenia in patients receiving TNF-blockers, including infliximab.
Danish: Der er set pancytopeni, leukopeni, neutropeni og trombocytopeni hos patienter, der fik TNF-hæmmere, herunder infliximab.
English: Zessly is indicated for treatment of severe, active Crohn's disease, in children and adolescents aged 6 to 17 years, who have not responded to conventional therapy including a corticosteroid, an immunomodulator and primary nutrition therapy; or who are intolerant to or have contraindications for such therapies.
Danish: Zessly er indiceret til behandling af svær, aktiv Crohns sygdom hos børn og unge mellem 6 og 17 år, som ikke har responderet på konventionel behandling inklusive kortikosteroid, immunmodulator og primær ernæringsbehandling, eller som er intolerante over for eller hvor der er kontraindikationer mod sådanne behandlinger.
English: Do not dilute the reconstituted Zessly solution with any other diluent.
Danish: Fortynd ikke det rekonstituerede Zesslykoncentrat med andre infusionsvæsker.
English: a control = All patients had active RA despite treatment with stable methotrexate doses for 6 months prior to enrolment and were to remain on stable doses throughout the study.
Danish: HAQ ændring fra baseline over tidene (patienter evalueret) Gennemsnit ± SDc a Kontrol = Alle patienter havde aktiv RA på trods af behandling med stabile methotrexat-doser i 6 måneder før inklusion og skulle fortsætte på stabile doser gennem studiet.
English: Ankylosing spondylitis is an inflammatory disease of the spine.
Danish: Ankyloserende spondylitis er en betændelsessygdom i rygraden.
English: It is recommended that live vaccines not be given concurrently with Zessly.
Danish: Levende vacciner bør ikke gives samtidig med Zessly.
English: After infliximab treatment, patients exhibited decreased levels of serum interleukin 6 (IL-6) and C-reactive protein (CRP), and increased haemoglobin levels in rheumatoid arthritis patients with reduced haemoglobin levels, compared with baseline.
Danish: Efter infliximab-behandling udviste patienter nedsat niveau af serum interleukin 6 (IL-6) og C-reaktiv protein (CRP).
English: IV use only
Danish: Kun til i.v.
English: Zessly is indicated for treatment of severely active ulcerative colitis, in children and adolescents aged 6 to 17 years, who have had an inadequate response to conventional therapy including corticosteroids and 6-MP or AZA, or who are intolerant to or have medical contraindications for such therapies.
Danish: Zessly er indiceret til behandling af svær, aktiv colitis ulcerosa hos børn og unge i alderen 6 til 17 år, som har responderet utilstrækkeligt på konventionel behandling, inklusive kortikosteroider og 6-MP eller AZA, eller som er intolerante over for eller hvor der er kontraindikationer mod disse behandlinger.
English: e
Danish: a
English: Re-administration for psoriatic arthritis
Danish: Fornyet indgift ved psoriasis arthritis
English: The safety and efficacy of infliximab have not been studied in children with ulcerative colitis below the age of 6 years.
Danish: Infliximabs sikkerhed og virkning hos børn under 6 år med colitis ulcerosa er ikke klarlagt.
English: Efficacy and safety of infliximab were assessed in two multicenter, double-blind, placebocontrolled studies 8 and 9 in patients with active ankylosing spondylitis (Bath Ankylosing
Danish: Infliximabs effekt og sikkerhed blev undersøgt i to multicenter, dobbelblind, placebokontrollerede studier hos 8 og 9, hos patienter med aktiv ankyloserende spondylitis (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI] score ≥ 4 og spinalsmerte ≥ 4 på en skala på 1-10).
English: Re-administration for ulcerative colitis
Danish: Fornyet indgift ved colitis ulcerosa
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu
Danish: Yderligere oplysninger om Zessly findes på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu
English: Tell your doctor straight away if you get signs of TB during treatment with Zessly.
Danish: Fortæl straks din læge, hvis du får tegn på TB under behandlingen med Zessly.
English: Maintenance treatment in moderately to severely active Crohn's disease in adults
Danish: Vedligeholdelsesbehandling af moderat til svært aktiv Crohns sygdom hos voksne
English: Zessly and Kineret should not be used together.
Danish: Du må ikke få Zessly og Kineret samtidig.
English: Signs include a fever, feeling tired, (persistent) cough, shortness of breath, weight loss, night sweats, diarrhoea, wounds, dental problems, burning when urinating or ‘flu-like' signs.
Danish: Tegn inkluderer feber, træthedsfølelse, (vedvarende) hoste, åndenød, vægttab, natlig svedtendens, diarré, sår, tandproblemer, en brændende smerte, når du lader vandet, eller influenzalignende symptomer.
English: Patients should be tested for HBV infection before initiating treatment with Zessly.
Danish: Før behandlingen med Zessly påbegyndes, skal patienten testes for HBV-infektion.
English: In patients who develop HBV reactivation, Zessly should be stopped and effective antiviral therapy with appropriate supportive treatment should be initiated.
Danish: Der er ikke tilgængelige data om antiviral behandling profylaktisk mod HBV-reaktivering i forbindelse med TNF-antagonist-behandling hos patienter, som er bærere af HBV. Zessly bør seponeres hos patienter, hvor HBV reaktiveres, og effektiv antiviral behandling med passende understøttende behandling bør igangsættes.
English: Tell your doctor straight away if you get symptoms of low blood counts during treatment with Zessly.
Danish: Fortæl det straks til lægen, hvis du får symptomer på lave blodtal under behandlingen med Zessly.
English: Tell your doctor straight away if you get signs of infection during treatment with Zessly.
Danish: Fortæl straks din læge, hvis du får tegn på infektion under behandling med Zessly.
English: In the paediatric Crohn's disease study, infections were reported in 56.3% of randomised subjects treated with infliximab.
Danish: Der blev rapporteret infektioner hos 56,3 % af de randomiserede personer behandlet med infliximab i studiet med Crohns sygdom hos børn.
English: Additional side effects in children and adolescents
Danish: Hos børn og unge ses yderligere følgende bivirkninger:
English: Zessly 100 mg powder for concentrate for solution for infusion infliximab
Danish: Zessly 100 mg pulver til koncentrat til infusionsvæske, opløsning infliximab
English: How to use Zessly Rheumatoid arthritis
Danish: Sådan får du Zessly Reumatoid arthritis
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS
Danish: MINDSTEKRAV TIL MÆRKNING PÅ SMÅ INDRE EMBALLAGER HÆTTEGLAS ETIKET
English: It is recommended that therapeutic infectious agents not be given concurrently with Zessly.
Danish: Terapeutiske smitstoffer bør ikke gives samtidig med Zessly.
English: After preparation each ml contains 10 mg of infliximab.
Danish: Efter klargøring indeholder hver ml 10 mg infliximab.
English: • Feeling numb or having a tingling feeling
Danish: • Følelsesløshed eller en prikkende fornemmelse.
English: It is recommended that therapeutic infectious agents not be given concurrently with Zessly (see section 4.4).
Danish: Terapeutiske smitstoffer bør ikke gives samtidig med Zessly (se pkt.
English: Tell your doctor straight away if you develop symptoms of lupus during treatment with Zessly.
Danish: Fortæl det straks til lægen, hvis du får symptomer på lupus under behandlingen med Zessly.
English: Tell your doctor straight away if you get symptoms of a nerve disease during treatment with Zessly.
Danish: Fortæl straks din læge, hvis du får symptomer på en nervesygdom under behandlingen med Zessly.
English: infliximab (week 16)
Danish: infliximab (uge 16)
English: Zessly 100 mg powder for concentrate for solution for infusion.
Danish: Zessly 100 mg pulver til koncentrat til infusionsvæske, opløsning.
English: infliximab (week 98)
Danish: infliximab (uge 98)
English: (pleurisy)
Danish: (børn)
English: infliximab (week 54)
Danish: infliximab (uge 54)
English: Common (may affect up to 1 in 10 people)
Danish: Almindelige: (kan forekomme hos op til 1 ud af 10 personer)
English: infliximab (week 24)
Danish: infliximab (uge 24)
English: Re-administration for ankylosing spondylitis
Danish: Fornyet indgift ved ankyloserende spondylitis
English: Uncommon (may affect up to 1 in 100 people)
Danish: Ikke almindelige: (kan forekomme hos op til 1 ud af 100 personer)
English: Percentage of subjects with mucosal healing
Danish: Procent forsøgspersoner med slimhindeheling
English: Rheumatoid arthritis Crohn's disease Paediatric Crohn's disease
Danish: Fornyet indgift ved Crohns sygdom og reumatoid arthritis
English: Induction treatment in moderately to severely active Crohn's disease
Danish: Induktionsbehandling af moderat til svært aktiv Crohns sygdom
English: Maintenance (n = 99)
Danish: (n = 112)
English: Maintenance treatment in fistulising active Crohn's disease
Danish: Vedligeholdelsesbehandling af fistulerende, aktiv Crohns sygdom
English: All nails cleared c
Danish: Alle negle fri for psoriasisc
English: During the 24-week double blind phase, patients received either 5 mg/kg infliximab or placebo at weeks 0, 2, 6, 14, and 22
Danish: Under den 24 ugers dobbeltblinde fase modtog patienterne enten 5 mg/kg infliximab eller placebo i ugerne 0, 2, 6, 14 og 22 (100 patienter i hver gruppe).
English: Patients treated with infliximab should be given the patient reminder card.
Danish: Patientinformationskortet skal udleveres til patienter, som er i behandling med infliximab.
English: • Inflamed lining of the lung, causing sharp chest pains that feel worse with breathing
Danish: • Lungehindebetændelse, der giver skape smerter, som forværres ved vejrtrækning (pleuritis)
English: Improvement from baseline in HAQ averaged over time from week 30 to week 54c
Danish: Median Forbedring fra baseline i HAQ gennemsnitligt over tid fra uge 30 til uge 54c Gennemsnit ± SDd a p < 0,001, for hver infliximab-behandlingsgruppe mod kontrol.
English: Tell your doctor straight away if you get symptoms of liver problems during treatment with Zessly.
Danish: Fortæl det straks til lægen, hvis du får symptomer på leverproblemer under behandlingen med Zessly.
English: Dizziness may occur following administration of infliximab (see section 4.8).
Danish: Der kan opstå svimmelhed under behandling med infliximab (se pkt.
English: Zessly is not likely to affect your ability to drive or use tools or machines.
Danish: Zessly påvirker sandsynligvis ikke arbejdssikkerheden eller evnen til at færdes sikkert i trafikken.
English: Change from baseline (Mean ± SDc) Median (Interquartile range)
Danish: Total scored (van der Heijde-modified Sharp score) Ændring fra baseline (Gennemsnit ± SDc ) Medianc (Interkvartil interval) Patienter uden forværring/patienter evalueret ( %)c
English: Induction treatment in fistulising active Crohn's disease
Danish: Induktionsbehandling af fistulerende, aktiv Crohns sygdom
English: Patients treated with Zessly should be given the package leaflet and the patient reminder card.
Danish: Indlægssedlen og patientinformationskortet skal gives til patienter, som behandles med Zessly.
English: • Tell your doctor if you have any abnormal skin openings (fistulae) before you are given
Danish: Unormale hudåbninger • Fortæl din læge, hvis du har unormale hudåbninger (fistler), før du får Zessly.
English: Steroid-Free Remission
Danish: Klinisk remission
English: Date:
Danish: Dato
English: Each Zessly vial contains 100 mg infliximab.
Danish: Hvert Zessly-hætteglas indeholder 100 mg infliximab.
English: Elevations of ALT ≥ 5 x Upper
Danish: ≥ 5 x ULN
English: 5 mg/kg given as an intravenous infusion followed by additional 5 mg/kg infusions at 2 and 6 weeks after the first infusion.
Danish: 5 mg/kg indgivet som en intravenøs infusion følges op med yderligere infusioner på 5 mg/kg, 2 og 6 uger efter den første infusion.
English: Respiratory, thoracic and mediastinal disorders
Danish: Luftveje, thorax og mediastinum Meget almindelig:
English: What Zessly looks like and contents of the pack
Danish: Udseende og pakningsstørrelser
English: Type 1 glass vial with rubber stopper and aluminium crimp protected by a plastic cap. Zessly is available in packs containing 1, 2, 3, 4 or 5 vials.
Danish: Hætteglas (type 1 glas med gummiprop og aluminiumshætte beskyttet med et plastiklåg).
English: How to store Zessly
Danish: Sådan får du Zessly
English: • Maintenance: Additional infusion of 5 mg/kg at 6 weeks after the initial dose, followed by infusions every 8 weeks or
Danish: • Vedligeholdelsesbehandling: Yderligere infusionsdosis på 5 mg/kg 6 uger efter den første dosis,
English: Malignancies, some fatal, have been reported among children, adolescents and young adults (up to
Danish: Efter markedsføring er der rapporteret maligniteter, hvoraf nogle har været letale, hos børn, unge og unge voksne (op til 22 år), som er behandlet med TNF-blokkere inklusive infliximab (behandlingsstart før 18-års alderen).
English: While using Zessly you should not receive live vaccines.
Danish: Du må ikke få levende vacciner, mens du får Zessly.
English: 22 years of age) treated with TNF-blocking agents (initiation of therapy ≤ 18 years of age),
Danish: Efter markedsføring er der set maligniteter, hvoraf nogle har været letale, hos børn, unge og unge voksne (op til 22 år), som er behandlet med TNF-blokerende midler (behandlingsstart før 18-års alderen), heriblandt infliximab.
English: 5 mg/kg given as an intravenous infusion followed by additional 5 mg/kg infusion doses at 2 and 6 weeks after the first infusion, then every 6 to 8 weeks.
Danish: 5 mg/kg givet som en intravenøs infusion efterfulgt af yderligere infusionsdoser på 5 mg/kg, 2 og 6 uger efter den første infusion, herefter hver 6. til 8. uge.
English: patients with NYHA Class III-IV CHF (left ventricular ejection fraction ≤ 35%) were treated with 3
Danish: I dette studie blev 150 patienter med NYHA funktionsklasse III-IV CHF (venstre ventrikels uddrivningsfraktion ≤ 35 %) behandlet med 3 infusioner infliximab 5 mg/kg, 10 mg/kg eller placebo i løbet af 6 uger.
English: mg/kg infliximab or placebo infusions at weeks 0, 2 and 6.
Danish: Patienterne fik enten 3 eller, 5 mg/kg infliximab eller placeboinfusioner i uge 0, 2 og 6.
English: Treatment is continued over a period of up to 72 hours.
Danish: Behandlingen fortsættes i indtil 72 timer.