FrancophonIA/ELRC3.0 huggingface dataset:
English: While the carcinogenic potential in humans is unknown, these data suggest that the clinical benefit of efavirenz outweighs the potential carcinogenic risk to humans.
Croatian: Premda nije poznat kancerogeni potencijal u ljudi, ovi podaci ukazuju na to da je klinička korist primjene efavirenza veća od potencijalnog kancerogenog rizika za ljude.
English: Your doctor has prescribed Efavirenz Teva for you because you have HIV infection.
Croatian: Liječnik Vam je propisao Efavirenz Teva jer ste zaraženi HIV-om.
English: Table 1: Interactions between efavirenz and other medicinal products in adults
Croatian: Tablica 1: Interakcije između efavirenza i drugih lijekova kod odraslih
English: If you are pregnant, you should take Efavirenz Teva only if you and your doctor decide it is clearly needed.
Croatian: Ako ste trudni, Efavirenz Teva smijete uzimati samo ako ste zajedno s liječnikom odlučili da je to neophodno.
English: Study ACTG 364 48 weeks
Croatian: Ispitivanje ACTG 48 tjedana
English: In addition, your doctor may prescribe a higher dose of Efavirenz Teva.
Croatian: Osim toga, liječnik Vam može propisati veću dozu Efavirenza Teva.
English: The incidence of erythema multiforme or Stevens-Johnson syndrome was approximately 0.1%.
Croatian: Incidencija erythema multiforme ili Stevens-Johnsonova sindroma bila je oko 0,1%.
English: It must always be taken in combination with other anti-HIV medicines.
Croatian: Uvijek se mora uzimati u kombinaciji s drugim lijekovima koji djeluju protiv HIV virusa.
English: Ketoconazole and other imidazole antifungals
Croatian: Ketokonazol i drugi imidazolski antifungici
English: (PLIVA Croatia Ltd.), Prilaz baruna Filipovića 25, 10000 Zagreb, Croatia
Croatian: Proizvođač PLIVA Hrvatska d.o.o. (PLIVA Croatia Ltd.), Prilaz baruna Filipovića 25, 10000 Zagreb, Hrvatska
English: - If you have a heart condition, such as changes in the rhythm or rate of the heart beat, a slow heart beat, or severe heart disease.
Croatian: • ako imate bolest srca, kao što su promjene ritma ili brzine otkucaja srca, usporene otkucaje srca ili tešku bolest srca.
English: 95% confidence intervals.
Croatian: b 95% intervali pouzdanosti.
English: Levonorgestrel (active metabolite):
Croatian: Levonorgestrel (aktivni metabolit):
English: Film-coated tablet Yellow, capsule-shaped, film-coated tablet debossed with “Teva” on one side and “7541” on the other
Croatian: Žuta filmom obložena tableta oblika kapsule, s utisnutom oznakom „Teva“ na jednoj i „7541“ na drugoj strani.
English: - if you have a heart disorder, such as abnormal electrical signal called prolongation of the QT interval.
Croatian: o ako imate srčani poremećaj, kao što je neuobičajeni električni signal, koji se naziva produljenje QT intervala.
English: Your doctor may require you to take a pregnancy test to ensure you are not pregnant before starting treatment with Efavirenz Teva.
Croatian: Vaš liječnik će možda zatražiti da napravite test na trudnoću kako biste bili sigurni da niste trudni prije nego što počnete liječenje Efavirenzom Teva.
English: Norelgestromin (active metabolite):
Croatian: Norelgestromin (aktivni metabolit):
English: What Efavirenz Teva is and what it is used for
Croatian: Što je Efavirenz Teva i za što se koristi
English: Dosing at bedtime seems to improve the tolerability of these symptoms and can be recommended during the first weeks of therapy and in patients who continue to experience these symptoms (see section 4.2).
Croatian: Uzimanje lijeka prije spavanja može poboljšati podnošljivost ovih simptoma, te se može preporučiti u prvim tjednima liječenja kao i za bolesnike u kojih se simptomi nastavljaju (vidjeti dio 4.2).
English: If you have severe liver disease, do not take Efavirenz Teva (see section 2,
Croatian: Ako imate tešku bolest jetre, nemojte uzimati Efavirenz Teva (vidjeti dio 2.
English: Total active HMG CoA reductase inhibitors:
Croatian: Ukupno aktivni inhibitori HMG Co-A reduktaze:
English: Therefore, you should continue to use contraceptive measures, as above, for 12 weeks after you stop taking Efavirenz Teva.
Croatian: Stoga, morate nastaviti koristiti kontracepcijske metode kako je gore navedeno još 12 tjedana nakon prestanka uzimanja Efavirenza Teva.
English: - severe depression - suicidal ideation - non-fatal suicide attempts - aggressive behaviour - paranoid reactions - manic reactions
Croatian: - teška depresija - suicidalna razmišljanja - pokušaji samoubojstva - agresivno ponašanje - paranoidne reakcije - manične reakcije
English: Antibiotics
Croatian: Antibiotici
English: 30 x 1 film-coated tablets.
Croatian: 30 x 1 filmom obloženih tableta.
English: If you had a rash while taking another NNRTI, you may be at a higher risk of getting a rash with Efavirenz Teva.
Croatian: Ako ste imali osip za vrijeme uzimanja nekog drugog NNRTI-ja, možete imati povećan rizik za dobivanje osipa s Efavirenzom Teva.
English: Any inflammatory symptoms should be evaluated and treatment instituted when necessary.
Croatian: Svaki od upalnih simptoma treba dijagnostički razjasniti i po potrebi uvesti odgovarajuće liječenje.
English: Consider doubling the rifabutin dose in regimens where rifabutin is given 2 or 3 times a week in combination with efavirenz.
Croatian: Treba razmotriti udvostručenje doze rifabutina u protokolima u kojima se rifabutin primjenjuje 2 ili 3 puta na tjedan u kombinaciji s efavirenzom.
English: Cmax and AUC were seen for doses up to 1,600 mg; the increases were less than proportional suggesting diminished absorption at higher doses.
Croatian: O dozi ovisno povišenje Cmax i AUC zabilježeno je kod primjena do 1600 mg; povišenja su bila manja od proporcionalnih, što upućuje na smanjenu apsorpciju lijeka pri većim dozama.
English: - Medicines used to treat malaria:
Croatian: - Lijekove za liječenje malarije:
English: If you are affected, do not drive and do not use any tools or machines.
Croatian: Ako primijetite opisane učinke, nemojte voziti niti raditi na strojevima ili s alatima.
English: - The dose for Efavirenz Teva may need to be increased or decreased if you are also taking certain medicines (see Other medicines and Efavirenz Teva).
Croatian: - Dozu lijeka Efavirenz Teva možda će trebati povisiti ili sniziti ako uzimate i neke druge lijekove (pogledajte Drugi lijekovi i Efavirenz Teva).
English: Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicinal product.
Croatian: Bolesnici s rijetkim nasljednim poremećajem nepodnošenja galaktoze, potpunim nedostatkom laktaze ili malapsorpcijom glukoze i galaktoze ne bi smjeli uzimati ovaj lijek.
English: Verapamil, felodipine, nifedipine and nicardipine
Croatian: Verapamil, felodipin, nifedipin i nikardipin
English: Long-term use of efavirenz in this study was not associated with any new safety concerns.
Croatian: Dugotrajna primjena efavirenza u ovom ispitivanju nije bila povezana s novim dvojbama u pogledu sigurnosti.
English: As neural tube defects occur within the first 4 weeks of foetal development (at which time neural tubes are sealed), this potential risk would concern women exposed to efavirenz during the first trimester of pregnancy.
Croatian: Budući da do oštećenja neuralne cijevi dolazi u prva 4 tjedna razvoja fetusa (kada se neuralna cijev zatvara), ovaj potencijalni rizik odnosi se na žene koje su izložene efavirenzu u prvom tromjesečju trudnoće.
English: Efavirenz has a relatively long terminal half-life of at least 52 hours after single doses and 40-55 hours after multiple doses.
Croatian: Efavirenz ima relativno dug terminalni poluvijek od najmanje 52 sata nakon primjene jednokratne doze, odnosno 40-55 sati nakon višekratne primjene.
English: Simvastatin acid:
Croatian: Simvastatinska kiselina:
English: Sertraline:
Croatian: Sertralin:
English: Clarithromycin 14-hydroxymetabolite:
Croatian: Klaritromicin 14-hidroksimetabolit:
English: Contents of the pack and other information What Efavirenz Teva contains
Croatian: Sadržaj pakiranja i druge informacije Što Efavirenz Teva sadrži
English: Efavirenz is highly bound (approximately 99.5-99.75%) to human plasma proteins, predominantly albumin.
Croatian: Efavirenz se u velikoj mjeri veže za proteine plazme (približno 99,5-99,75%), pretežno za albumin.
English: Substitutions at RT positions 98, 100, 101, 108, 138, 188, 190 or 225 were also observed, but at lower frequencies, and often only in combination with K103N.
Croatian: Zabilježene su i zamjene u reverznoj transkriptazi na mjestima 98, 100, 101, 108, 138, 188, 190 ili 225, ali su bile rjeđe i često tek u kombinaciji s
English: Since use of two NNRTIs proved not beneficial in terms of efficacy and safety, co-administration of efavirenz and another NNRTI is not recommended.
Croatian: Kako se primjena dva NNRTI-ja nije pokazala korisnom u smislu djelotvornosti i neškodljivosti, ne preporučuje se istodobna primjena efavirenza i drugog NNRTI-ja.
English: Efavirenz Teva with food and drink
Croatian: Efavirenz Teva s hranom i pićem
English: Contraception in males and females
Croatian: Kontracepcija kod muškaraca i žena
English: Cmax: ↓ 24% (↓ 18 to ↓ 30) These changes are not considered clinically significant.
Croatian: Cmax: ↓ 24% (↓ 18 do ↓ 30) Te se promjene ne smatraju klinički značajnima.
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant product information for these medicinal products.
Croatian: U slučaju istodobnog liječenja antivirusnom lijekom protiv hepatitisa B ili C, molimo proučiti i uputu o lijeku priloženu za taj lijek.
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Croatian: Znakovi osteonekroze su ukočenost zglobova, bolovi u zglobovima (osobito u kuku, koljenu ili ramenu) i poteškoće pri kretanju.
English: Carcinogenicity studies showed an increased incidence of hepatic and pulmonary tumours in female mice, but not in male mice.
Croatian: Istraživanja kancerogenosti pokazala su povećanu incidenciju jetrenih i plućnih tumora kod ženki miševa, ali ne i kod mužjaka.
English: Cholesterol levels should be periodically monitored.
Croatian: Razine kolesterola treba periodički kontrolirati.
English: If you see any signs of a severe rash with blistering or fever, stop taking Efavirenz Teva and tell your doctor at once.
Croatian: Ako opazite bilo kakve znakove jakog osipa s mjehurićima ili vrućicom, odmah prestanite uzimati Efavirenz Teva i javite se svom liječniku.
English: If you have taken Efavirenz Teva or the combination tablet containing efavirenz, emtricitabine, and tenofovir during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Croatian: Ako ste tijekom trudnoće uzimali Efavirenz Teva ili kombiniranu tabletu koja sadrži efavirenz, emtricitabin i tenofovir, Vaš liječnik može zatražiti redovne krvne i druge dijagnostičke pretrage kako bi pratio razvoj Vašeg djeteta.
English: Efavirenz is not recommended for patients who have had a life-threatening cutaneous reaction (e.g., Stevens-Johnson syndrome) while taking another NNRTI.
Croatian: Efavirenz se ne preporučuje bolesnicima koji su imali po život opasne kožne reakcije (primjerice Stevens-Johnsonov sindrom) tijekom uzimanja nekog drugog NNRTI-a.
English: Patients should be advised that if they experience symptoms such as severe depression, psychosis or suicidal ideation, they should contact their doctor immediately to assess the possibility that the symptoms may be related to the use of efavirenz, and if so, to determine whether the risks of continued therapy outweigh the benefits (see section 4.8).
Croatian: Bolesnike treba uputiti da se, u slučaju pojave simptoma poput teške depresije, psihoze ili suicidalnih razmišljanja, odmah jave liječniku koji će procijeniti da li su ti simptomi povezani s primjenom efavirenza te, ako jesu, odrediti da li je rizik od nastavka liječenja veći od moguće koristi (vidjeti dio 4.8).
English: (see section 4.3).
Croatian: (vidjeti dio 4.4).
English: The daily dose of rifabutin should be increased by 50% when administered with efavirenz.
Croatian: Dnevnu dozu rifabutina treba povećati za 50% kad se primjenjuje s efavirenzom.
English: any signs of skin rash.
Croatian: o bilo kakve znakove kožnog osipa.
English: Interactions between efavirenz and protease inhibitors, antiretroviral agents other than protease inhibitors and other non-antiretroviral medicinal products are listed in Table 1 below (increase is indicated as “↑”, decrease as “↓”, no change as “↔”, and once every 8 or 12 hours as “q8h” or “q12h”).
Croatian: Interakcije između efavirenza i inhibitora proteaze, drugih antiretrovirusnih lijekova osim inhibitora proteaze te drugih lijekova koji nisu antiretrovirusni, popisane su u Tablici 1 (povećanje je označeno kao „↑“, smanjenje kao „↓“, bez promjene kao „↔“, a jedanput svakih 8 ili 12 sati kao „q8h“ ili „q12h“).
English: Tests may show: - increased cholesterol in the blood
Croatian: Pretrage mogu pokazati: - povišene razine kolesterola u krvi
English: The standard doses of NRTIs given every 12 hours were used in each of these studies.
Croatian: U svakom od tih ispitivanja davale su se standardne doze NRTI-ja svakih 12 sati.
English: In some cases, your doctor may need to adjust your dose or check your blood levels.
Croatian: U nekim slučajevima Vaš liječnik će Vam možda morati prilagoditi dozu ili provjeriti koncentracije lijeka u krvi.
English: Biliary fibrosis has been observed in rats.
Croatian: Kod štakora je zapažena bilijarna fibroza.
English: - The dose for adults is 600 mg once daily.
Croatian: - Doza lijeka za odrasle je 600 mg jedanput na dan.
English: Patients with a history of psychiatric disorders appear to be at greater risk of these serious psychiatric adverse reactions with frequencies ranging from 0.3% for manic reactions to 2.0% for both severe depression and suicidal ideation.
Croatian: Čini se da bolesnici s psihijatrijskim bolestima u anamnezi imaju veći rizik za razvoj ovih ozbiljnih psihijatrijskih nuspojava, čija se učestalost u njih kreće od 0,3% za manične reakcije do 2,0% za tešku depresiju i suicidalna razmišljanja.
English: How to store Efavirenz Teva Contents of the pack and other information
Croatian: Kako čuvati Efavirenz Teva Sadržaj pakiranja i druge informacije
English: Despite the decrease in buprenorphine exposure, no patients exhibited withdrawal symptoms.
Croatian: Usprkos smanjenju izloženosti buprenorfinu, niti jedan bolesnik nije imao simptome ustezanja.
English: Severe rash associated with blistering, moist desquamation or ulceration has been reported in less than 1% of patients treated with efavirenz.
Croatian: Jaki osip povezan s nastajanjem mjehura, vlažnom deskvamacijom ili ulceracijama bio je prijavljen u manje od 1% bolesnika liječenih efavirenzom.
English: - You must remain under the care of your doctor while taking Efavirenz Teva.
Croatian: • Morate ostati pod nadzorom svog liječnika dok uzimate Efavirenz Teva.
English: - Medicines that impact heart rhythm: Medicines used to treat heart rhythm problems: such as flecainide or metoprolol.
Croatian: lijekovi koji utječu na srčani ritam: lijekovi koji se koriste za liječenje problema srčanog ritma: kao što su flekainid ili metoprolol.
English: When treating HIV infection, it is not always possible to tell whether some of the unwanted effects are caused by Efavirenz Teva or by other medicines that you are taking at the same time, or by the HIV disease itself.
Croatian: Kod liječenja HIV infekcije, nije uvijek moguće procijeniti jesu li neke nuspojave nastale zbog primjene lijeka Efavirenz Teva ili drugih lijekova koji se istodobno uzimaju, ili zbog same HIV bolesti.
English: In one study, nervous system symptoms often occurred during the first 1-3 hours after taking a dose.
Croatian: U jednom su se ispitivanju simptomi živčanog sustava često pojavljivali u prvih 1-3 sata nakon uzimanja doze lijeka.
English: In the long-term study (006), 1% of patients in each treatment arm discontinued because of liver or biliary system disorders.
Croatian: U dugotrajnoj studiji (006) 1% bolesnika iz svake ispitivane skupine prekinulo je liječenje zbog poremećaja u funkciji jetre ili žuči.
English: Telaprevir (relative to 750 mg q8h):
Croatian: Telaprevir (750 mg q8h):
English: This medicine contains 9.98 mg lactose (as monohydrate) per tablet.
Croatian: Ovaj lijek sadrži 9,98 mg laktoze (u obliku hidrata) po tableti.
English: The clinical outcome of this observed reduction of boceprevir trough concentrations has not been directly assessed.
Croatian: Klinički ishod tog zamijećenog smanjenja koncentracija boceprevira nije procijenjen izravno.
English: Taking Efavirenz Teva on an empty stomach may reduce the undesirable effects.
Croatian: Uzimanjem Efavirenza Teva na prazan želudac mogu se smanjiti nuspojave.
English: - Efavirenz Teva must be taken with other medicines that act against the HIV virus.
Croatian: • Efavirenz Teva mora se uzimati s drugim lijekovima koji djeluju protiv HIV virusa.
English: Insufficient numbers of elderly patients have been evaluated in clinical studies to determine whether they respond differently than younger patients.
Croatian: Klinička su ispitivanja provedena na nedovoljnom broju starijih bolesnika da bi se mogla utvrditi razlika u odgovoru na liječenje od onoga u mlađih bolesnika.
English: Mean Cmin µg/mL
Croatian: Cmin µg/ml
English: The free concentration of efavirenz required for 90 to 95% inhibition of wild type or zidovudine-resistant laboratory and clinical isolates in vitro ranged from 0.46 to 6.8 nM in lymphoblastoid cell lines, peripheral blood mononuclear cells (PBMCs) and macrophage/monocyte cultures.
Croatian: Slobodne koncentracije efavirenza potrebne za 90-95%-tnu inhibiciju laboratorijskih i kliničkih izolata divljih tipova ili tipova rezistentnih na zidovudin in vitro, kretale su se između 0,46 i 6,8 nM u limfoblastoidnim staničnim linijama, mononuklearnim stanicama periferne krvi (PBMC) i u kulturama makrofaga/monocita.
English: In uninfected volunteers, multiple doses of 200-400 mg per day for 10 days resulted in a lower than predicted extent of accumulation (22-42% lower) and a shorter terminal half-life compared with single dose administration (see below).
Croatian: U nezaraženih je dobrovoljaca primjena višekratnih doza od 200-400 mg na dan tijekom 10 dana dovela do manje akumulacije lijeka od predviđene (22-42% niže) i kraćeg terminalnog poluvijeka u usporedbi s primjenom jednokratne doze (vidjeti nastavak teksta).
English: Patients should be informed that if they do occur, these common symptoms are likely to improve with continued therapy and are not predictive of subsequent onset of any of the less frequent psychiatric symptoms.
Croatian: Bolesnike treba obavijestiti da će ovi uobičajeni simptomi, ako se pojave, uglavnom smanjiti u nastavku liječenja te da nisu predznak razvoja bilo kojeg od manje čestih psihijatrijskih simptoma.
English: If you could get pregnant while receiving Efavirenz Teva, you need to use a reliable form of barrier contraception (for example, a condom) with other methods of contraception including oral (pill) or other hormonal contraceptives (for example, implants, injection).
Croatian: Ako biste mogli zatrudnjeti dok uzimate Efavirenz Teva, morate koristiti pouzdanu mehaničku kontracepciju (na primjer, prezervativ) zajedno s drugim metodama kontracepcije, uključujući kontracepcijske tablete ili druge oblike hormonske kontracepcije (na primjer, implantat ili injekcije).
English: Ethinyloestradiol:
Croatian: Etiniloestradiol:
English: Antimalarials
Croatian: Antimalarici
English: (Inhibition of CYP-mediated oxidative metabolism) When efavirenz was given with ritonavir 500 mg or 600 mg twice daily, the combination was not well tolerated (for example, dizziness, nausea, paraesthesia and elevated liver enzymes occurred).
Croatian: (inhibicija oksidativnog metabolizma posredovanog CYP-om) Pri primjeni efavirenza s ritonavirom u dozi od 500 mg ili 600 mg dvaput na dan, ta se kombinacija nije dobro podnosila (na primjer, javile su se omaglica, mučnina, parestezija i povišene vrijednosti jetrenih enzima).
English: The potency of efavirenz in cell culture against viral variants with amino acid substitutions at positions 48, 108, 179, 181 or 236 in RT or variants with amino acid substitutions in the protease was similar to that observed against wild-type viral strains.
Croatian: U staničnim kulturama potentnost efavirenza protiv virusnih inačica sa zamijenjenim aminokiselinama na mjestima 48, 108, 179, 181 ili 236 u reverznoj transkriptazi (RT), ili inačica sa zamijenjenim aminokiselinama u proteazi, bila je slična onoj zabilježenoj prema divljim sojevima virusa.
English: Do not use this medicine after the expiry date which is stated on the blister and on the carton after EXP.
Croatian: Ovaj lijek ne smije se upotrijebiti nakon isteka roka valjanosti navedenog na blisteru i kutiji iza „EXP“.
English: Although limited data suggest that females as well as Asian and Pacific Island patients may have higher exposure to efavirenz, they do not appear to be less tolerant of efavirenz.
Croatian: Premda ograničeni podaci ukazuju na to da je izloženost efavirenzu viša u žena, kao i u Azijaca i bolesnika s pacifičkih otoka, čini se da u njih ne postoji razlika u podnošljivosti efavirenza.
English: Intermittent monotherapy and sequential reintroduction of antiretroviral agents is not advisable because of the increased potential for selection of resistant virus.
Croatian: Monoterapija s prekidima i sekvencijsko ponovo uvođenje antiretrovirusnih lijekova ne preporučuje se zbog povećane mogućnosti selekcije rezistentnog virusa.
English: With efavirenz, an increase of the lopinavir/ritonavir soft capsule or oral solution doses by 33% should be considered (4 capsules/ ~6.5 ml twice daily instead of 3 capsules/5 ml twice daily).
Croatian: Uz efavirenz, mora se razmotriti povećanje doze lopinavir/ritonavir mekih kapsula ili oralne otopine za 33% (4 kapsule/~6,5 ml dvaput na dan umjesto 3 kapsule/5 ml dvaput na dan).
English: This mutation was observed in 90% of patients receiving efavirenz with virological failure.
Croatian: Ta je mutacija zapažena u 90% bolesnika koji su primali efavirenz s terapijskim neuspjehom.
English: Cross-resistance profiles for efavirenz, nevirapine and delavirdine in cell culture demonstrated that the K103N substitution confers loss of susceptibility to all three NNRTIs.
Croatian: Profili križne rezistencije za efavirenz, nevirapin i delavirdin u staničnim kulturama pokazali su da zamjena K103N dovodi do gubitka osjetljivosti na sva tri NNRTI-ja.
English: In HIV-1 infected patients (n = 9) who received efavirenz 200 to 600 mg once daily for at least one month, cerebrospinal fluid concentrations ranged from 0.26 to 1.19% (mean 0.69%) of the corresponding plasma concentration.
Croatian: U bolesnika zaraženih HIV-1 virusom (n=9) koji su primali efavirenz u dozama od 200 do 600 mg jedanput na dan tijekom najmanje mjesec dana, koncentracije lijeka u cerebrospinalnoj tekućini kretale su se u rasponu od 0,26-1,19% (prosječno 0,69%) odgovarajućih koncentracija u plazmi.
English: < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); or very rare (< 1/10,000).
Croatian: Učestalost nuspojava definirana je sljedećim izrazima: vrlo često (≥1/10), često (≥1/100 do <1/10), manje često (≥1/1000 do <1/100), rijetko (≥1/10 000 do <1/1000) i vrlo rijetko (<1/10 000).
English: Cetirizine:
Croatian: Cetirizin:
English: Approximately 14-34% of a radiolabelled dose of efavirenz was recovered in the urine and less than 1% of the dose was excreted in urine as unchanged efavirenz.
Croatian: Približno 14-34% radioaktivno označenog efavirenza pronađeno je u mokraći, a manje od 1% doze izlučuje se mokraćom u nepromijenjenom obliku.
English: The clinical implications of such an association are unknown; however, the potential for an increased frequency and severity of efavirenz-associated adverse events cannot be excluded.
Croatian: Klinički značaj ove povezanosti nije poznat; međutim, ne može se isključiti mogućnost učestalijih i težih štetnih događaja povezanih s primjenom efavirenza.