FrancophonIA/ELRC3.0 huggingface dataset:
English: Dupilumab is a monoclonal antibody (a type of specialised protein) that blocks the action of proteins called IL-4 and IL-13.
Croatian: Dupilumab je monoklonsko protutijelo (jedna vrsta specijaliziranog proteina) koje blokira djelovanje proteina zvanih IL-4 i IL-3.
English: Table 6: Results of the primary and secondary endpoints in CAFE study Placebo + TCS
Croatian: Tablica 6: Rezultati za primarnu i sekundarne mjere ishoda u ispitivanju CAFE Placebo + TKS
English: Do not use the pre-filled pen if the window is yellow.
Croatian: Nemojte upotrijebiti napunjenu brizgalicu ako je prozorčić žute boje.
English: Remove yellow cap
Croatian: Skinite žuti zatvarač
English: Patients receiving concomitant oral corticosteroids may reduce their steroid dose once clinical improvement with dupilumab has occurred (see section 5.1).
Croatian: Bolesnici koji istodobno primaju oralne kortikosteroide mogu smanjiti dozu steroida nakon što nastupi kliničko poboljšanje tijekom liječenja dupilumabom (vidjeti dio 5.1).
English: Efficacy with respect to severe asthma exacerbations and lung function was observed in both adolescents and adults.
Croatian: Djelotvornost s obzirom na teške egzacerbacije astme i plućnu funkciju opažena je i u adolescenata i u odraslih.
English: SOLO 2 at Week 16
Croatian: SOLO 2 u 16. tjednu
English: Dupilumab is administered by subcutaneous injection into the thigh or abdomen, except for the 5 cm around the navel.
Croatian: Dupilumab se primjenjuje supkutanom injekcijom u bedro ili abdomen, osim područja 5 cm oko pupka.
English: • Place the orange needle cover on your skin at approximately a 90-degree angle.
Croatian: • Položite narančasti pokrov igle na kožu pod kutom od približno 90°.
English: Patients with pre-existing helminth infections should be treated before initiating dupilumab.
Croatian: Bolesnike s postojećim infekcijama helmintima treba liječiti prije uvođenja dupilumaba.
English: Clinical Response in Patients Not Adequately Controlled with, Intolerant to, or for whom Ciclosporin Treatment was Inadvisable (CAFE study)
Croatian: Klinički odgovor u bolesnika kojima stanje nije dovoljno dobro kontrolirano ciklosporinom, koji ne podnose ciklosporin ili za koje se liječenje ciklosporinom ne preporučuje (ispitivanje CAFE)
English: Inject your medicine immediately after removing the needle cap.
Croatian: Lijek injicirajte odmah nakon što skinete zatvarač igle.
English: Conjunctivitis allergic Eye pruritus Blepharitis
Croatian: Poremećaji oka često alergijski konjunktivitis očni pruritus blefaritis
English: Dupixent is unlikely to influence your ability to drive and use machines.
Croatian: Nije vjerojatno da će Dupixent utjecati na Vašu sposobnost upravljanja vozilima ili rada sa strojevima.
English: The improvement in pruritus NRS occurred in conjunction with the improvement of objective signs of atopic dermatitis.
Croatian: Poboljšanje NRS rezultata za pruritus nastupilo je zajedno s poboljšanjem objektivnih znakova atopijskog dermatitisa.
English: If patients become infected while receiving treatment with dupilumab and do not respond to antihelminth treatment, treatment with dupilumab should be discontinued until infection resolves.
Croatian: Ako se bolesnici zaraze dok primaju dupilumab i ne odgovaraju na liječenje antihelminticima, liječenje dupilumabom treba prekinuti dok se infekcija ne povuče.
English: Prepare the injection site
Croatian: Pripremite mjesto injiciranja
English: After a single subcutaneous (SC) dose of 75-600 mg dupilumab, median times to maximum concentration in serum (tmax) were 3-7 days.
Croatian: Apsorpcija Nakon jedne supkutane (s.c.) doze dupilumaba od 75 - 600 mg, medijan vremena do maksimalne koncentracije u serumu (tmax) iznosio je 3 - 7 dana.
English: • Dispose of the pre-filled pens, (needle inside), and yellow caps in a puncture resistant container right away after use.
Croatian: • Brizgalice (u kojima se nalazi igla) i žute zatvarače odložite u neprobojni spremnik odmah nakon uporabe.
English: Reductions in corticosteroid dose, if appropriate, should be gradual and performed under the direct supervision of a physician.
Croatian: Ako je moguće smanjiti dozu kortikosteroida, to treba učiniti postupno i pod izravnim nadzorom liječnika.
English: Keep holding the pre-filled pen firmly against your skin.
Croatian: Držite čvrsto Nastavite držati napunjenu brizgalicu čvrsto pritisnutom o kožu.
English: Reduction in corticosteroid dose may be associated with systemic withdrawal symptoms and/or unmask conditions previously suppressed by systemic corticosteroid therapy.
Croatian: Smanjenje doze kortikosteroida može biti povezano sa sistemskim simptomima ustezanja i/ili razotkriti stanja koja je liječenje sistemskim kortikosteroidima dotad suprimiralo.
English: The medium ICS dose was defined as equal to 500 mcg fluticasone or equivalent per day.
Croatian: Umjerena doza IKS-a definirala se kao doza od 500 µg flutikazona ili ekvivalenta na dan.
English: Immunogenicity As with all therapeutic proteins, there is a potential for immunogenicity with dupilumab.
Croatian: Kao i svi terapijski proteini, dupilumab može imati imunogeno djelovanje.
English: The pre-filled syringe should not be exposed to heat or direct sunlight and should not be shaken.
Croatian: Napunjena štrcaljka ne smije se izlagati toplini ni izravnoj sunčevoj svjetlosti i ne smije se tresti.
English: In these 5 trials, 1,689 subjects were treated with subcutaneous injections of dupilumab, with or without concomitant topical corticosteroids (TCS).
Croatian: U tih je 5 ispitivanja 1689 bolesnika bilo liječeno supkutanim injekcijama dupilumaba, uz istodobnu primjenu topikalnih kortikosteroida (TKS) ili bez njih.
English: This should be taken into consideration to determine type 2 status in patients taking oral corticosteroids (see section
Croatian: O tome treba voditi računa pri određivanju statusa tipa 2 u bolesnika koji uzimaju oralne kortikosteroide (vidjeti dio 5.1).
English: 300 mg (≥60 kg)
Croatian: kg) ili 300 mg (≥60 kg)
English: Using Dupixent for atopic dermatitis (atopic eczema) can improve the condition of your skin and reduce itching.
Croatian: Primjena lijeka Dupixent za atopijski dermatitis (atopijski ekcem) može poboljšati stanje kože i ublažiti svrbež.
English: • When placing the orange needle cover on your skin, hold the pre-filled pen so that you can see the window.
Croatian: • Kod postavljanja narančastog pokrova igle na kožu uhvatite brizgalicu tako da vidite prozorčić.
English: Of the 1,472 patients with atopic dermatitis exposed to dupilumab in a phase 2 dose-ranging study or phase 3 placebo-controlled studies, a total of 67 were 65 years or older.
Croatian: Od 1472 bolesnika s atopijskim dermatitisom izložena dupilumabu u ispitivanju faze 2 kojim se utvrđivao raspon doza ili u placebom kontroliranim ispitivanjima faze 3, ukupno je 67 bolesnika bilo u dobi od 65 ili više godina.
English: If needed to control intolerable symptoms of atopic dermatitis, patients were permitted to receive rescue treatment (which included higher potency topical steroids or systemic immunosuppressants) at the discretion of the investigator.
Croatian: Ako je to bilo potrebno za kontroliranje nepodnošljivih simptoma atopijskog dermatitisa, bolesnicima je bilo dopušteno primati „rescue” lijekove za hitno ublažavanje simptoma (koji su uključivali topikalne steroide veće potentnosti ili sistemske imunosupresive) prema odluci ispitivača.
English: Tell your doctor immediately if you develop a combination of symptoms such as a flu-like illness, pins and needles or numbness of arms or legs, worsening of pulmonary symptoms, and/or rash.
Croatian: Odmah obavijestite svog liječnika ako se kod Vas pojavi kombinacija simptoma kao što su bolest nalik gripi, trnci ili utrnulost ruku ili nogu, pogoršanje plućnih simptoma i/ili osip.
English: It is unknown whether dupilumab is excreted in human milk or absorbed systemically after ingestion.
Croatian: Nije poznato izlučuje li se dupilumab u majčino mlijeko niti dolazi li do njegove sistemske apsorpcije nakon ingestije.
English: • After you have completed your injection pull straight up to remove pre-filled pen from the skin.
Croatian: • Nakon što završite injekciju, povucite brizgalicu ravno prema gore da biste je uklonili s kože.
English: Dupilumab trough concentrations were lower in subjects with higher body weight with no meaningful impact on efficacy.
Croatian: Najniže koncentracije dupilumaba bile su niže u ispitanika veće tjelesne težine, ali to nije značajno utjecalo na djelotvornost.
English: Treatment effects in subgroups (weight, age, gender, race, and background treatment, including immunosuppressants) in CHRONOS were consistent with the results in the overall study population.
Croatian: Terapijski učinci u podskupinama (tjelesna težina, dob, spol, rasa i osnovno liječenje, uključujući imunosupresive) u ispitivanju CHRONOS bili su u skladu s rezultatima u cjelokupnoj ispitivanoj populaciji.
English: Both play a major role in causing the signs and symptoms of asthma.
Croatian: Oba ta proteina igraju veliku ulogu u izazivanju znakova i simptoma astme.
English: Pharmacotherapeutic group: Other dermatological preparations, agents for dermatitis, excluding corticosteroids, ATC code: D11AH05
Croatian: 5.1 Farmakodinamička svojstva Farmakoterapijska skupina: Ostali dermatološki pripravci, pripravci za dermatitis, isključujući kortikosteroide, ATK oznaka: D11AH05
English: Annualized rate of severe asthma exacerbation events during the 24-week placebo controlled treatment period was also determined.
Croatian: Određivala se i godišnja stopa događaja teških egzacerbacija astme tijekom 24-tjednog placebom kontroliranog razdoblja liječenja.
English: • You can inject into your thigh or belly (stomach), except for the 5 cm around your navel.
Croatian: • Lijek možete injicirati u bedro ili trbuh, osim područja 5 cm oko pupka.
English: In the event of overdosage, monitor the patient for any signs or symptoms of adverse reactions and institute appropriate symptomatic treatment immediately.
Croatian: U slučaju predoziranja potrebno je nadzirati bolesnika zbog moguće pojave znakova ili simptoma nuspojava te odmah uvesti odgovarajuće simptomatsko liječenje.
English: Dupixent helps prevent severe asthma attacks (exacerbations) and can improve your breathing.
Croatian: Dupixent pomaže spriječiti teške napadaje astme (egzacerbacije) te može poboljšati disanje.
English: Placebo + TCS
Croatian: Placebo + TKS
English: 52-Week Concomitant TCS Study (CHRONOS)
Croatian: 52-tjedno ispitivanje istodobne primjene topikalnih kortikosteroida (CHRONOS)
English: If you use more Dupixent than you should or the dose has been given too early, talk to your doctor, pharmacist or nurse.
Croatian: Ako primijenite više lijeka Dupixent nego što ste trebali ili ako primite dozu prerano, obratite se svom liječniku, ljekarniku ili medicinskoj sestri.
English: Always keep the container out of the reach of children.
Croatian: Uvijek čuvajte spremnik izvan dohvata djece.
English: Therefore, patients receiving dupilumab may receive concurrent inactivated or non-live vaccinations.
Croatian: Stoga bolesnici koji se liječe dupilumabom mogu istodobno primiti inaktivirana ili neživa cjepiva.
English: Dupixent has also been shown to improve symptoms of pain, anxiety, and depression associated with atopic dermatitis.
Croatian: Pokazalo se da Dupixent ublažava i simptome boli, tjeskobe i depresije povezane s atopijskim dermatitisom.
English: • 1 cotton ball or gauze*
Croatian: • 1 komad pamučne vate ili gazu*
English: Fertility studies conducted in male and female mice using a surrogate antibody against IL-4Rα showed no impairment of fertility (see section 4.6).
Croatian: Ispitivanja učinaka na plodnost provedena na mužjacima i ženkama miševa uz pomoć zamjenskog protutijela protiv IL-4Rα nisu pokazala štetne učinke na plodnost (vidjeti dio 4.6).
English: The safety profile of dupilumab in patients followed through week 52 was similar to the safety profile observed at week 16 in AD-1526 study.
Croatian: Sigurnosni profil dupilumaba praćen u bolesnika do 52. tjedna bio je sličan sigurnosnom profilu zabilježenom u 16. tjednu ispitivanja AD-1526.
English: Immune responses to TdaP vaccine and meningococcal polysaccharide vaccine were assessed, see section 4.5.
Croatian: Ocijenjeni su imuni odgovori na cjepivo TdaP i meningokokno polisaharidno cjepivo, vidjeti dio 4.5.
English: Do not give yourself a second dose without speaking to your healthcare provider.
Croatian: Nemojte primijeniti još jednu dozu bez prethodnog razgovora sa svojim zdravstvenim radnikom.
English: Immune responses to vaccination were assessed in a study in which patients with atopic dermatitis were treated once weekly for 16 weeks with 300 mg of dupilumab.
Croatian: Imuni odgovori na cijepljenje ocjenjivali su se u ispitivanju u kojem su se bolesnici s atopijskim dermatitisom liječili dupilumabom u dozi od 300 mg jedanput na tjedan tijekom 16 tjedana.
English: ICS = inhaled corticosteroid; FEV1 = Forced expiratory volume in 1 second; ACQ-5 = Asthma Control Questionnaire-5; AQLQ = Asthma Quality of Life Questionnaire; AD = atopic dermatitis; NP = nasal polyposis; AR = allergic rhinitis; FeNO = fraction of exhaled nitric oxide; EOS = blood eosinophil aThe population in dupilumab asthma trials included patients on medium and high dose ICS.
Croatian: IKS = inhalacijski kortikosteroid; FEV1 (forced expiratory volume in 1 second) = forsirani izdisajni volumen u 1 sekundi; ACQ-5 (Asthma Control Questionnaire-5) = upitnik o kontroli astme od 5 pitanja; AQLQ (Asthma Quality of Life Questionnaire) = upitnik o kvaliteti života kod astme; AD = atopijski dermatitis; NP = nosna polipoza; AR = alergijski rinitis; FeNO = frakcija izdahnutog dušikova oksida a Populacija u ispitivanjima dupilumaba kod astme uključivala je bolesnike koji su uzimali umjerenu i visoku dozu IKS-a.
English: • Then lift the pen up off the skin, your injection is complete.
Croatian: • Zatim polako brojite do 5. • Zatim podignite brizgalicu s kože, injekcija je završena.
English: The recommended dose of dupilumab for adults and adolescents (12 years of age and older) is:
Croatian: Preporučena doza dupilumaba za odrasle i adolescente (u dobi od 12 ili više godina) je:
English: • If you see any blood at the site, lightly dab a cotton ball or gauze pad.
Croatian: • Ako na mjestu injiciranja vidite krv, nježno pritisnite komad pamučne vate ili gaze.
English: A caregiver may also give you your Dupixent injection after proper training.
Croatian: Injekciju lijeka Dupixent može Vam dati i skrbnik nakon što prođe propisnu obuku.
English: Look at the medicine through the window on the pre-filled pen.
Croatian: Pregledajte lijek kroz prozorčić na napunjenoj brizgalici.
English: Rarely patients taking an asthma medicine may develop inflammation of blood vessels or lungs due to an increase of certain white blood cells (eosinophilia).
Croatian: U rijetkim slučajevima kod bolesnika koji uzimaju lijekove za astmu može doći do upale krvnih žila ili pluća zbog povećanog broja jedne vrste bijelih krvnih stanica (eozinofilije).
English: No dose adjustment for body weight is recommended for patients with asthma 12 years of age and older or in adults with atopic dermatitis (see section 5.2).
Croatian: Ne preporučuje se prilagođavati dozu na temelju tjelesne težine u bolesnika s astmom u dobi od 12 ili više godina i u odraslih bolesnika s atopijskim dermatitisom (vidjeti dio 5.2).
English: For clinical data in adults with atopic dermatitis please refer to the dupilumab 300 mg Summary of Product Characteristics.
Croatian: Za kliničke podatke u odraslih osoba s atopijskim dermatitisom molimo pogledati Sažetak opisa svojstava lijeka za dupilumab od 300 mg.
English: 81 Columbia Turnpike
Croatian: REGENERON PHARMACEUTICALS INC. 81 Columbia Turnpike RENSSELAER
English: Treatment should be initiated by healthcare professionals experienced in the diagnosis and treatment of conditions for which dupilumab is indicated (see section 4.1).
Croatian: 4.2 Doziranje i način primjene Liječenje trebaju započeti zdravstveni radnici s iskustvom u dijagnosticiranju i liječenju stanja za koja je dupilumab indiciran (vidjeti dio 4.1).
English: You must not try to give yourself or someone else the injection unless you have received training from your healthcare professional.
Croatian: Ne smijete sami pokušati injicirati lijek sebi ili nekome drugome ako Vas zdravstveni radnik nije obučio kako se to radi.
English: Dupixent may also help reduce the amount of another group of medicines you need to control your asthma, called oral corticosteroids, while preventing severe asthma attacks and improving your breathing.
Croatian: Dupixent također može pomoći smanjiti količinu oralnih kortikosteroida (još jedne vrste lijekova koje morate uzimati za kontrolu astme), a pritom spriječiti teške napadaje astme i poboljšati disanje.
English: Safety and efficacy in paediatric patients (< 12 years of age) with severe asthma have not been established.
Croatian: Sigurnost i djelotvornost u pedijatrijskih bolesnika (u dobi od < 12 godina) s teškom astmom nisu ustanovljene.
English: Quality of Life/Patient-Reported Outcomes in Asthma
Croatian: Kvaliteta života/ishodi koje prijavljuju bolesnici kod astme
English: Dupilumab should not be used to treat acute bronchospasm or status asthmaticus.
Croatian: Dupilumab se ne smije primjenjivati za liječenje akutnog bronhospazma ili astmatičnog statusa.
English: The baseline mean oral corticosteroid use was 11.75 mg in the placebo group and 10.75 mg in the group receiving dupilumab.
Croatian: Početna srednja vrijednost doze oralnih kortikosteroida iznosila je 11,75 mg u skupini koja je primala placebo te 10,75 mg u onoj koja je primala dupilumab.
English: Patients being treated for asthma may present with serious systemic eosinophilia sometimes presenting with clinical features of eosinophilic pneumonia or vasculitis consistent with eosinophilic granulomatosis with polyangiitis, conditions which are often treated with systemic corticosteroid therapy.
Croatian: Bolesnici koji se liječe zbog astme mogu imati ozbiljnu sistemsku eozinofiliju, koja se ponekad manifestira kliničkim značajkama eozinofilne pneumonije ili vaskulitisa koji odgovara eozinofilnoj granulomatozi praćenoj poliangitisom - stanjima koja se često liječe sistemskim kortikosteroidima.
English: The primary endpoint was the percent reduction in oral corticosteroid dose assessed in the overall population, based on a comparison of the oral corticosteroid dose at weeks 20 to 24 that maintained asthma control with the previously optimized (at baseline) oral corticosteroid dose.
Croatian: Primarna mjera ishoda bilo je postotno smanjenje doze oralnih kortikosteroida u cjelokupnoj populaciji, na temelju usporedbe doze oralnih kortikosteroida u razdoblju od 20. do 24. tjedna kojom se održavala kontrola astme i prethodno optimizirane doze oralnih kortikosteroida (koja se primjenjivala na početku ispitivanja).
English: For single use only Subcutaneous use
Croatian: Samo za jednokratnu uporabu Supkutana primjena
English: Do not stop or reduce your asthma medicines, unless instructed by your doctor.
Croatian: Nemojte prestati primjenjivati svoje lijekove za astmu niti smanjiti njihovu dozu ako Vam to ne kaže liječnik.
English: The pre-filled syringe or the pre-filled pen should not be exposed to heat or direct sunlight and should not be shaken.
Croatian: Napunjena štrcaljka ili napunjena brizgalica ne smije se izlagati toplini ni izravnoj sunčevoj svjetlosti i ne smije se tresti.
English: Treatment effects in subgroups (weight, age, gender, race, and background treatment, including immunosuppressants) in SOLO 1 and SOLO 2 were consistent with the results in the overall study population.
Croatian: Terapijski učinci u podskupinama (tjelesna težina, dob, spol, rasa i osnovno liječenje, uključujući imunosupresive) u ispitivanjima SOLO 1 i SOLO 2 bili su u skladu s rezultatima u cjelokupnoj ispitivanoj populaciji.
English: Of the 1,977 patients with asthma exposed to dupilumab, a total of 240 patients were 65 years or older and 39 patients were 75 years or older.
Croatian: Od 1977 bolesnika s astmom izloženih dupilumabu, ukupno je 240 bolesnika bilo u dobi od 65 ili više godina, dok je 39 bolesnika bilo u dobi od 75 ili više godina.
English: In SOLO CONTINUE, a trend for increased treatment-emergent ADA positivity with increased dosing intervals was observed.
Croatian: U ispitivanju SOLO CONTINUE je kod povećanja intervala doziranja opažen trend porasta pozitivnosti na protutijela na lijek koja su nastala tijekom liječenja.
English: Do not inject through clothes.
Croatian: Nemojte injicirati lijek kroz odjeću.
English: What you need to know before you use Dupixent 3.
Croatian: Što morate znati prije nego počnete primjenjivati Dupixent
English: Patients were also permitted to use topical calcineurin inhibitors (TCI).
Croatian: Bolesnicima je bilo dopušteno primjenjivati i topikalne inhibitore kalcineurina.
English: DRI12544 was a 24-week dose-ranging study which included 776 patients (18 years of age and older).
Croatian: Ispitivanje DRI12544 bilo je 24-tjedno ispitivanje radi utvrđivanja raspona doza, a obuhvatilo je 776 bolesnika (u dobi od 18 ili više godina).
English: During a reproductive toxicology study conducted in monkeys, using a surrogate antibody specific to the monkey IL-4Rα, no fetal abnormalities were observed at dosages that saturate the IL-4Rα.
Croatian: Tijekom ispitivanja reproduktivne toksičnosti na majmunima, u kojem se koristilo zamjensko protutijelo specifično za majmunski IL-4Rα, nisu opažene abnormalnosti ploda pri dozama koje zasićuju IL-4Rα.
English: Primary and secondary endpoints for the 52 week SOLO CONTINUE study are summarized in table 7.
Croatian: Primarne i sekundarne mjere ishoda za 52-tjedno ispitivanja SOLO CONTINUE sažeto su prikazane u Tablici 7.
English: The asthma development program included three randomised, double-blind, placebo-controlled, parallel-group, multi-centre studies (DRI12544, QUEST, and VENTURE) of 24 to 52 weeks in treatment duration which enrolled a total of 2,888 patients (12 years of age and older).
Croatian: Razvojni program lijeka kod astme uključivao je tri randomizirana, dvostruko slijepa, placebom kontrolirana, multicentrična ispitivanja s paralelnim skupinama (DRI12544, QUEST i VENTURE) u kojima je liječenje trajalo od 24 do 52 tjedna i u koja je bilo uključeno ukupno 2888 bolesnika (u dobi od 12 ili više godina).
English: The most common adverse reaction was injection site erythema.
Croatian: Najčešća nuspojava bio je eritem na mjestu injiciranja.
English: Mean age (years) (SD) % Female % White
Croatian: Srednja vrijednost dobi (godine) (SD) Žene, %
English: c Patients who received rescue treatment or with missing data were considered as non-responders (58.8% and 20.7% in the placebo and dupilumab arms, respectively).
Croatian: c Bolesnici koji su primili terapiju za hitno ublažavanje simptoma ili za koje su nedostajali podaci smatrali su se bolesnicima bez odgovora (58,8 u placebo skupini i 20,7 % u skupini dupilumaba).
English: • Do not inject through clothes.
Croatian: • Nemojte injicirati lijek kroz odjeću.
English: A larger percentage of patients randomised to placebo needed rescue treatment (topical corticosteroids, systemic corticosteroids, or systemic non-steroidal immunosuppressants) as compared to the dupilumab group (58.8% and 20.7%, respectively).
Croatian: Veći postotak bolesnika randomiziranih u skupinu koja je primala placebo trebao je „rescue“ liječenje (topikalne kortikosteroide ili sistemske nesteroidne imunosupresive) u usporedbi sa skupinom koja je primala dupilumab (58,8% u odnosu na 20,7%).
English: Name and address of the manufacturer(s) responsible for batch release SANOFI WINTHROP INDUSTRIE 1051 Boulevard Industriel,
Croatian: Naziv(i) i adresa(e) proizvođača odgovornog(ih) za puštanje serije lijeka u promet SANOFI WINTHROP INDUSTRIE
English: • Never pull back on the plunger rod.
Croatian: • Nikada nemojte povlačiti natrag potisnik klipa.
English: Inject Dupixent yourself only after you have been trained by your doctor or nurse.
Croatian: Injicirajte Dupixent sami tek nakon što Vam liječnik ili medicinska sestra pokažu kako se to radi.