FrancophonIA/ELRC3.0 huggingface dataset:
English: Clinical trials of up to more than 2 years' duration did not show any additional safety signals or unforeseen risks when vildagliptin was added on to metformin.
Danish: Kliniske forsøg af op til over 2 års varighed viste ingen yderligere sikkerhedssignaler eller uforudsete risici, når vildagliptin blev lagt til metformin.
English: Another two-year carcinogenicity study was conducted in mice at oral doses up to 1,000 mg/kg.
Danish: Der blev udført endnu et toårigt karcinogenicitetsstudie på mus med orale doser på op til 1.000 mg/kg.
English: If you stop taking Jalra
Danish: Hvis du holder op med at tage Jalra
English: * p< 0.05 for comparison versus placebo + comparator
Danish: * p< 0,05 for sammenligning mod placebo + sammenligningsstof
English: It is unknown whether vildagliptin is excreted in human milk.
Danish: Det er ukendt, om vildagliptin udskilles i human mælk.
English: Jalra is used to treat adult patients with type 2 diabetes.
Danish: Jalra bruges til at behandle voksne patienter med type 2-diabetes (sukkersyge).
English: Jalra is not recommended for use in children and adolescents (< 18 years).
Danish: Jalra bør ikke anvendes til børn og unge (< 18 år).
English: Overall, vildagliptin improved glycaemic control when given as monotherapy or when used in combination with metformin, a sulphonylurea, and a thiazolidinedione, as measured by clinically relevant reductions in HbA1c from baseline at study endpoint (see Table 8).
Danish: Generelt forbedrede vildagliptin den glykæmiske kontrol, når det blev givet som monoterapi eller kombineret med metformin, et sulfonylurinstof, eller et glitazon, målt ved klinisk relevante reduktioner af HbA1c fra baseline ved studiets endpoint (se tabel 8).
English: Jalra contains lactose (milk sugar).
Danish: Jalra indeholder lactose (mælkesukker).
English: A clinical trial of vildagliptin in patients with New York Heart Association NYHA functional class I-III showed that treatment with vildagliptin was not associated with a change in left-ventricular function or worsening of pre-existing congestive heart failure (CHF) versus placebo.
Danish: Et klinisk studie med vildagliptin hos patienter med New York Heart Association (NYHA) funktionsklasse I-III-hjerteinsufficiens viste, at behandling med vildagliptin ikke var forbundet med en ændring i venstre ventrikels funktion eller forværring af allerede eksisterende kongestiv hjerteinsufficiens (CHF), sammenlignet med placebo.
English: Patients treated with vildagliptin reported significantly lower incidences of gastrointestinal adverse reactions versus those treated with metformin.
Danish: De patienter, der blev behandlet med vildagliptin, rapporterede signifikant lavere incidens af gastrointestinale bivirkninger i forhold til de patienter, der blev behandlet med metformin.
English: Skin lesions, including blistering and ulceration have been reported in extremities of monkeys in nonclinical toxicology studies (see section 5.3).
Danish: Hudlæsioner, herunder blære- og sårdannelse, er rapporteret på ekstremiteterne i aber i non-kliniske toksikologi undersøgelser (se pkt.
English: • 100 mg daily taken as 50 mg in the morning and 50 mg in the evening if you are taking Jalra alone, with another medicine called metformin or a glitazone, with a combination of metformin and a sulphonylurea, or with insulin.
Danish: • 100 mg daglig som 50 mg om morgenen og 50 mg om aftenen, hvis du tager Jalra alene, sammen med anden medicin kaldet metformin eller et glitazon, sammen med en kombination af metformin og et sulfonylurinstof eller sammen med insulin.
English: Clinical trials of up to 2 years' duration did not show any additional safety signals or unforeseen risks with vildagliptin monotherapy.
Danish: Kliniske forsøg af op til 2 års varighed viste ingen yderligere sikkerhedssignaler eller uforudsete risici med vildagliptin monoterapi.
English: Vildagliptin is not metabolised by CYP 450 enzymes to any quantifiable extent.
Danish: Vildagliptin metaboliseres ikke af CYP 450-enzymer i målbart omfang.
English: Placebo-corrected mean change in HbA1c (%) at week 24 (95% CI)
Danish: Placebokorrigeret gennemsnitlig ændring i HbA1c (%) ved uge 24 (95 %CI)
English: The safety and efficacy of vildagliptin as triple oral therapy in combination with metformin and a thiazolidinedione have not been established.
Danish: Sikkerheden og virkningen af vildagliptin som trippelbehandling i kombination med metformin og et glitazon er ikke klarlagt.
English: Clinical experience in patients with NYHA functional class III treated with vildagliptin is still limited and results are inconclusive (see section 5.1).
Danish: Den kliniske erfaring hos patienter med NYHA funktionsklasse III, der behandles med vildagliptin, er stadig begrænset, og resultaterne er ikke entydige (se pkt.
English: • if you are allergic to vildagliptin or any of the other ingredients of this medicine (listed in section 6).
Danish: • hvis du er allergisk over for vildagliptin eller et af de øvrige indholdsstoffer i Jalra (angivet i pkt.
English: When used as monotherapy, in combination with metformin, in combination with thiazolidinedione, in combination with metformin and a sulphonylurea, or in combination with insulin (with or without metformin), the recommended daily dose of vildagliptin is 100 mg, administered as one dose of 50 mg in the morning and one dose of 50 mg in the evening.
Danish: Når Jalra anvendes som monoterapi, i kombination med metformin, i kombination med glitazon, i kombination med metformin og et sulfonylurinstof eller i kombination med insulin (med eller uden metformin), er den anbefalede daglige dosis af vildagliptin 100 mg, administreret som én dosis på 50 mg om morgenen og én dosis på 50 mg om aftenen.
English: No clinically relevant differences in the pharmacokinetics of vildagliptin were observed between male and female healthy subjects within a wide range of age and body mass index (BMI).
Danish: Der blev ikke observeret nogen klinisk relevante forskelle i vildagliptins farmakokinetik hos mandlige og kvindelige forsøgspersoner inden for et bredt interval af alder og BMI.
English: Aluminium/Aluminium (PA/Al/PVC//Al) blister Available in packs containing 7, 14, 28, 30, 56, 60, 90, 112, 180 or 336 tablets and in multipacks containing 336 (3 packs of 112) tablets.
Danish: Aluminium/Aluminium-blister (PA/Al/PVC//Al) Fås i pakninger med 7, 14, 28, 30, 56, 60, 90, 112, 180 eller 336 tabletter og i multipakninger indeholdende 336 (3 pakker med 112) tabletter.
English: Patients who develop jaundice or other signs suggestive of liver dysfunction should discontinue Jalra.
Danish: Patienter, der udvikler gulsot eller andre symptomer, som tyder på leverdysfunktion, bør ophøre behandling med Jalra.
English: • Liver disease (hepatitis) (rare): Symptoms include yellow skin and eyes, nausea, loss of appetite or dark-coloured urine, which may indicate liver disease (hepatitis).
Danish: • Leversygdom (hepatitis) (sjælden): Symptomerne inkluderer gul hud og øjne, kvalme, nedsat appetit eller mørk urin, hvilket kan tyde på en leversygdom (hepatitis)
English: Mean change from baseline in HbA1c (%) at week 24
Danish: Gennemsnitlig ændring fra baseline i HbA1c (%) ved uge 24
English: • if you are taking an anti-diabetic medicine known as a sulphonylurea (your doctor may want to reduce your dose of the sulphonylurea when you take it together with Jalra in order to avoid low blood glucose [hypoglycaemia]).
Danish: • hvis du tager medicin mod diabetes, kaldet sulfonylurinstof (for at undgå at du får lavt blodsukker [hypoglykæmi], vil din læge måske nedsætte din dosis af sulfonylurinstoffet, når du tager det sammen med Jalra).
English: Monotherapy placebo controlled studies
Danish: Placebokontrollerede monoterapistudier
English: The effect of impaired hepatic function on the pharmacokinetics of vildagliptin was studied in patients with mild, moderate and severe hepatic impairment based on the Child-Pugh scores (ranging from 6 for mild to 12 for severe) in comparison with healthy subjects.
Danish: Virkningen af nedsat leverfunktion på vildagliptins farmakokinetik blev studeret hos patienter med let, moderat og stærkt nedsat leverfunktion baseret på Child-Pugh-scorerne (der går fra 6 for let til 12 for svær) sammenlignet med raske forsøgspersoner.
English: Vildagliptin, a member of the islet enhancer class, is a potent and selective DPP-4 inhibitor.
Danish: Vildagliptin tilhører klassen af ø-celle-forstærkere og er en potent og selektiv DPP-4-hæmmer.
English: • Inflammation of the pancreas (pancreatitis) (frequency not known): Symptoms include severe and persistent pain in the abdomen (stomach area), which might reach through to your back, as well as nausea and vomiting.
Danish: • Betændelse i bugspytkirtlen (pankreatitis) (hyppighed ikke kendt): Symptomerne inkluderer stærke og vedvarende smerter i maven, der eventuelt breder sig til ryggen, samt kvalme og opkastning
English: Some patients have had the following side effects while taking Jalra alone:
Danish: Nogle patienter har oplevet følgende bivirkninger, mens de tog Jalra alene:
English: Jalra 50 mg tablets
Danish: Jalra 50 mg tabletter
English: • Angioedema (rare: may affect up to 1 in 1,000 people): Symptoms include swollen face, tongue or throat, difficulty swallowing, difficulties breathing, sudden onset rash or hives, which may indicate a reaction called “angioedema”.
Danish: • Angioødem (sjælden: kan forekomme hos op til 1 ud af 1.000 patienter): Symptomerne inkluderer hævet ansigt, tunge eller hals, synkebesvær, vejrtrækningsbesvær, pludselig optræden af udslæt eller nældefeber, som kan tyde på en reaktion kaldet ”angioødem”
English: As dual oral therapy in combination with - metformin, in patients with insufficient glycaemic control despite maximal tolerated dose of monotherapy with metformin, - a sulphonylurea, in patients with insufficient glycaemic control despite maximal tolerated dose of a sulphonylurea and for whom metformin is inappropriate due to contraindications or intolerance, - a thiazolidinedione, in patients with insufficient glycaemic control and for whom the use of a thiazolidinedione is appropriate.
Danish: Som oral behandling kombineret med - metformin hos patienter med utilstrækkelig glykæmisk kontrol på metformin-monoterapi på trods af maksimalt tolereret dosis metformin - et sulfonylurinstof hos patienter med utilstrækkelig glykæmisk kontrol på trods af maksimalt tolereret dosis sulfonylurinstof, og til hvem metformin ikke er egnet på grund af kontraindikationer eller intolerans - et glitazon hos patienter med utilstrækkelig glykæmisk kontrol, og til hvem et glitazon er egnet.
English: The safety and efficacy of Jalra in children and adolescents (< 18 years) have not been established.
Danish: Jalras sikkerhed og virkning hos børn og unge (< 18 år) er ikke klarlagt.
English: If you forget to take Jalra
Danish: Hvis du har glemt at tage Jalra
English: Vildagliptin is also indicated for use in combination with insulin (with or without metformin) when diet and exercise plus a stable dose of insulin do not provide adequate glycaemic control.
Danish: Vildagliptin er også indiceret i kombination med insulin (med eller uden metformin) når diæt, motion samt insulin ved stabil dosis ikke udviser tilstrækkelig glykæmisk kontrol.
English: Vildagliptin cannot be removed by haemodialysis.
Danish: Vildagliptin kan ikke fjernes ved hæmodialyse.
English: Children and adolescents The use of Jalra in children and adolescents up to 18 years of age is not recommended.
Danish: Børn og unge Jalra anbefales ikke til børn og unge under 18 år.
English: Study 2301: Vildagliptin 50 mg twice daily (N=90) Study 2384: Vildagliptin 50 mg twice daily (N=79)
Danish: Studie 2301: Vildagliptin 50 mg to gange daglig (N=90) Studie 2384: Vildagliptin 50 mg to gange daglig (N=79)
English: In clinical trials, the magnitude of HbA1c reductions with vildagliptin was greater in patients with higher baseline HbA1c.
Danish: I kliniske studier var størrelsen af HbA1c-reduktionerne med vildagliptin større hos patienter med højere baseline HbA1c.
English: Mean baseline HbA1c (%)
Danish: Gennemsnitlig baselineHbA1c (%)
English: Jalra should not be used in patients with hepatic impairment, including patients with pre-treatment alanine aminotransferase (ALT) or aspartate aminotransferase (AST) > 3x the upper limit of normal (ULN) (see also sections 4.4 and 5.2).
Danish: Jalra må ikke anvendes til patienter med nedsat leverfunktion, inklusive patienter der før behandlingstidspunktet har alanin-aminotransferase (ALAT) eller aspartat-aminotransferase (ASAT) > 3x den øvre normale grænseværdi (ULN) (se også pkt.
English: Vildagliptin AUC increased on average 1.4, 1.7 and 2-fold in patients with mild, moderate and severe renal impairment, respectively, compared to normal healthy subjects.
Danish: Vildagliptin-AUC blev øget gennemsnitlig 1,4, 1,7 og 2 gange hos patienter med henholdsvislet, moderat og svært nedsat nyrefunktion sammenlignet med normale raske personer.
English: The noeffect dose in rats was 25 mg/kg (5-fold human exposure based on AUC) and in mice 750 mg/kg (142fold human exposure).
Danish: NOEL hos rotter var 25 mg/kg (5 gange den humane eksponering baseret på AUC) og hos mus 750 mg/kg (142 gange den humane eksponering).
English: If a dose of Jalra is missed, it should be taken as soon as the patient remembers.
Danish: Hvis en dosis af Jalra glemmes, skal den tages så snart patienten kommer i tanke om det. En dobbeltdosis bør ikke tages på samme dag.
English: • Frequency not known (cannot be estimated from the available data): Itchy rash, inflammation of the pancreas, localised peeling of skin or blisters, muscle pain
Danish: • Hyppighed ikke kendt (kan ikke estimeres ud fra forhåndenværende data): Kløende udslæt, betændelse i bugspytkirtlen, områder med afskalning af huden eller blærer i huden, muskelsmerter
English: There were more cardiac events in vildagliptin treated patients with NYHA class III heart failure compared to placebo.
Danish: Der var flere hjerterelaterede hændelser hos vildagliptin-behandlede patienter med NYHA funktionsklasse III-hjertesvigt sammenlignet med placebo.
English: Jalra 50 mg tablets are available in packs containing 7, 14, 28, 30, 56, 60, 90, 112, 180 or 336 tablets and in multipacks comprising 3 cartons, each containing 112 tablets.
Danish: Jalra 50 mg tabletter fås i pakninger med 7, 14, 28, 30, 56, 60, 90, 112, 180 eller 336 tabletter samt i multipakninger bestående af 3 pakker, som hver indeholder 112 tabletter.
English: Combination with ACE-inhibitors
Danish: Kombination med ACE-hæmmere
English: Mean reductions were -1.20% with vildagliptin and -1.48% with rosiglitazone in patients with mean baseline HbA1c of 8.7%.
Danish: Middelreduktionerne var -1,20 % med vildagliptin og -1,48 % med rosiglitazon hos patienter med en gennemsnitlig baseline-HbA1c på 8,7 %.
English: What you need to know before you take Jalra
Danish: Det skal du vide, før du begynder at tage Jalra
English: In this patient population, vildagliptin 100 mg daily was no more effective than vildagliptin 50 mg once daily.
Danish: I denne patientpopulation var vildagliptin 100 mg daglig ikke mere virksomt end vildagliptin 50 mg én gang daglig.
English: Each tablet contains 50 mg vildagliptin.
Danish: Hver tablet indeholder 50 mg vildagliptin.
English: When used in combination with a sulphonylurea, a lower dose of the sulphonylurea may be considered to reduce the risk of hypoglycaemia.
Danish: Ved anvendelse i kombination med et sulfonylurinstof kan en lavere dosis sulfonylurinstof overvejes for at nedsætte risikoen for hypoglykæmi.
English: 2,682 patients were treated with vildagliptin 100 mg daily (either 50 mg twice daily or 100 mg once daily) and 1,102 patients were treated with vildagliptin 50 mg once daily.
Danish: 2.682 patienter blev behandlet med 100 mg vildagliptin daglig (50 mg to gange daglig eller 100 mg én gang daglig) og 1.102 patienter blev behandlet med 50 mg vildagliptin én gang daglig.
English: In healthy elderly subjects (≥ 70 years), the overall exposure of vildagliptin (100 mg once daily) was increased by 32%, with an 18% increase in peak plasma concentration as compared to young healthy subjects (18-40 years).
Danish: Hos raske ældre forsøgspersoner (≥ 70 år) steg den samlede eksponering for vildagliptin (100 mg en gang daglig) med 32 %, og den maksimale plasmakoncentration steg med 18 % sammenlignet med unge raske forsøgspersoner (18-40 år).
English: As triple oral therapy in combination with - a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.
Danish: Som oral trippelbehandling kombineret med - et sulfonylurinstof og metformin når diæt, motion og behandling med disse to lægemidler ikke udviser tilstrækkelig glykæmisk kontrol.
English: A multiple-dose, open-label trial was conducted to evaluate the pharmacokinetics of the lower therapeutic dose of vildagliptin (50 mg once daily) in patients with varying degrees of chronic renal impairment defined by creatinine clearance (mild: 50 to <80 ml/min, moderate: 30 to <50 ml/min and severe: <30 ml/min) compared to normal healthy control subjects.
Danish: Et multidosis, åbent studie blev udført for at vurdere farmakokinetikken af den lave terapeutiske dosis af vildagliptin (50 mg en gang daglig) hos patienter med forskellige grader af kronisk nedsat nyrefunktion defineret ved kreatininclearance (let: 50 til < 80 ml/min, moderat: 30 til < 50 ml/min og svær: < 30 ml/min) sammenlignet med normale raske kontrolpersoner.
English: • 50 mg daily taken as one dose in the morning if you are taking Jalra with another medicine called a sulphonylurea.
Danish: • 50 mg daglig, som du tager på én gang om morgenen, hvis du tager Jalra sammen med anden medicin, kaldet sulfonylurinstof.
English: In the subgroup with NYHA class III, the decrease in HbA1c compared to placebo was lower (difference 0.3%) but this conclusion is limited by the small number of patients (n=44).
Danish: Hos patienter i undergruppen med NYHA funktionsklasse III var faldet i HbA1c sammenlignet med placebo mindre (forskel på 0,3%), men denne konklusion begrænses af det lille patientantal (n=44).
English: Add-on / Combination studies Vildagliptin 50 mg twice daily + metformin (N=143) Vildagliptin 50 mg daily + glimepiride (N=132) Vildagliptin 50 mg twice daily + pioglitazone (N=136) Vildagliptin 50 mg twice daily + metformin + glimepiride (N=152)
Danish: Tillægs-/kombinationsstudier Vildagliptin 50 mg to gange daglig + metformin (N=143) Vildagliptin 50 mg daglig + glimepirid (N=132) Vildagliptin 50 mg to gange daglig + pioglitazon (N=136) Vildagliptin 50 mg to gange daglig + metformin + glimepirid (N=152)
English: The incidence of peripheral oedema when vildagliptin 100 mg daily was added to a maximum dose of background pioglitazone (45 mg once daily) was 7.0%, compared to 2.5% for background pioglitazone alone.
Danish: Forekomsten af perifert ødem, når vildagliptin 100 mg daglig blev anvendt i tillæg til maksimal dosis af baggrunds-pioglitazon (45 mg én gang daglig), var 7,0 %, sammenlignet med 2,5 % for baggrundspioglitazon alene.
English: Jalra should not be used during breast-feeding.
Danish: Jalra bør ikke anvendes under amning.
English: Confirmed heart failure (HF) events defined as HF requiring hospitalisation or new onset of HF were reported in 41 (0.43%) vildagliptin-treated patients and 32 (0.45%) comparator-treated patients with M-H RR 1.08 (95% CI 0.68-1.70).
Danish: Bekræftet hjertesvigtshændelser, defineret som hjertesvigt med behov for hospitalsindlæggelse eller nye tilfælde af hjertesvigt, blev rapporteret for 41 (0,43%) patienter behandlet med vildagliptin og for 32 (0,45%) patienter behandlet med komparatorer med en M-H RR på 1,08 (95% CI 0,68-1,70)..
English: The incidence of hypoglycaemia in the overall population was 4.7% and 5.6% in the vildagliptin and placebo groups, respectively.
Danish: Forekomsten af hypoglykæmi i den totale population var 4,7 % og 5,6 % i henholdsvis vildagliptin-gruppen og placebo-gruppen.
English: Treatment with vildagliptin 50-100 mg daily in patients with type 2 diabetes significantly improved markers of beta cell function including HOMA- (Homeostasis Model Assessment-), proinsulin to insulin ratio and measures of beta cell responsiveness from the frequently-sampled meal tolerance test.
Danish: Behandling med vildagliptin 50-100 mg daglig hos patienter med type 2-diabetes forbedrede markørerne for betacellefunktionen signifikant, herunder HOMA- (Homeostasis Model Assessment-), forholdet mellem proinsulin og insulin og målinger af betacellereaktionsevnen fra den hyppigst anvendte måltidstolerancetest.
English: More than 5,000 male and more than 4,000 female patients received vildagliptin 50 mg once daily or 100 mg daily.
Danish: Mere end 5.000 mandlige patienter og mere end 4.000 kvindelige patienter fik vildagliptin 50 mg en gang daglig eller 100 mg daglig.
English: • Common: Weight increase, swollen hands, ankle or feet (oedema)
Danish: • Almindelige: Vægtøgning, hævede hænder, ankler eller fødder (ødem)
English: More than 1,900 patients receiving vildagliptin 50 mg once daily or 100 mg daily were ≥ 65 years.
Danish: Mere end 1.900 af de patienter, som fik vildagliptin 50 mg én gang daglig eller 100 mg daglig, var ≥ 65 år.
English: In a 52-week double-blind controlled trial, vildagliptin (50 mg twice daily) reduced baseline HbA1c by -1% compared to -1.6% for metformin (titrated to 2 g/day) statistical non-inferiority was not achieved.
Danish: I et 52-ugers dobbeltblindet kontrolleret forsøg reducerede vildagliptin (50 mg to gange daglig) baseline-HbA1c med - 1 % sammenlignet med -1,6 % for metformin (titreret til 2 g daglig) blev statistisk non-inferioritet ikke opnået.
English: The usual dose of Jalra is either:
Danish: Den sædvanlige dosis er:
English: Safety data were obtained from a total of 3,784 patients exposed to vildagliptin at a daily dose of 50 mg (once daily) or 100 mg (50 mg twice daily or 100 mg once daily) in controlled trials of at least 12 weeks duration.
Danish: Der er indhentet sikkerhedsdata fra i alt 3.784 patienter, som blev eksponeret for vildagliptin med en daglig dosis på 50 mg (én gang daglig) eller 100 mg (50 mg to gange daglig eller 100 mg én gang daglig) i kontrollerede forsøg af mindst 12 ugers varighed.
English: Jalra contains lactose
Danish: Jalra indeholder lactose
English: • Very rare: Sore throat, runny nose, fever
Danish: • Meget sjældne: Ondt i halsen, løbende næse, feber
English: Clinical studies performed with healthy subjects have shown no clinically relevant pharmacokinetic interactions.
Danish: Kliniske studier med raske forsøgspersoner har ikke vist nogen klinisk relevante farmakokinetiske interaktioner.
English: • Common: Dizziness
Danish: • Almindelig: Svimmelhed
English: Patients receiving rosiglitazone experienced a mean increase in weight (+1.6 kg) while those receiving vildagliptin experienced no weight gain (-0.3 kg).
Danish: Patienter, der fik rosiglitazon, oplevede en gennemsnitlig vægtstigning (+1,6 kg), mens de, der fik vildagliptin, ikke oplevede nogen vægtstigning (-0,3 kg).
English: Jalra 50 mg tablets vildagliptin
Danish: Jalra 50 mg tabletter vildagliptin
English: A test to determine your liver function will be performed before the start of Jalra treatment, at threemonth intervals for the first year and periodically thereafter.
Danish: Du vil få taget en blodprøve til undersøgelse af din leverfunktion, før du starter med Jalrabehandlingen, med tre måneders interval i det første år og derefter regelmæssigt.
English: DPP-4 inhibition by vildagliptin is not affected by gender.
Danish: Vildagliptins DPP-4hæmning er ikke afhængig af køn.
English: When used in dual combination with a sulphonylurea, the recommended dose of vildagliptin is 50 mg once daily administered in the morning.
Danish: Når Jalra kombineres med et sulfonylurinstof, er den anbefalede dosis af vildagliptin 50 mg én gang daglig om morgenen.
English: In these cases, the patients were generally asymptomatic without clinical sequelae and liver function returned to normal after discontinuation of treatment.
Danish: I disse tilfælde var patienterne generelt asymptomatiske uden kliniske følgetilstande og leverfunktionstest blev normale efter ophør med behandlingen.