FrancophonIA/ELRC3.0 huggingface dataset:
English: Nervous system disorders common dizziness uncommon neuropathy peripheral rare cortical blindness transient, neurotoxicities (e.g., somnolence and fatigue), optic neuritis, seizure**
Danish: Nervesystemet almindelig svimmelhed ikke almindelig perifer neuropati sjælden forbigående kortikal blindhed, neurotoksiciteter (f.eks. somnolens og træthed), opticusneuritis, krampeanfald**
English: The mean renal clearance of etoposide is 7 to 10 mL/min/m2 or about 35% of the total body clearance over a dose range of 80 to 600 mg/m2.
Danish: Gennemsnitlig renal clearance af etoposid er 7 til 10 ml/min/m2 eller cirka 35 % af kroppens totale clearance i et dosisområde på 80 til 600 mg/m2.
English: Physicians should be aware of the possible occurrence of an anaphylactic reaction with VEPESID and associated names, manifested by chills, pyrexia, tachycardia, bronchospasm, dyspnoea and hypotension, which can be fatal.
Danish: Læger skal være opmærksomme på muligheden for en anafylaktisk reaktion med VEPESID og associerede navne, som giver sig udtryk ved kulderystelser, pyreksi, takykardi, bronkospasme, dyspnø og hypotension, som kan have letal udgang.
English: Skin and subcutaneous tissue disorders very common alopecia, pigmentation common pruritus, rash, urticaria rare radiation recall dermatitis, StevensJohnsons syndrome, toxic epidermal necrolysis
Danish: Hud og subkutane væv meget almindelig alopeci, pigmentering almindelig kløe, udslæt, nældefeber sjælden radiation recall dermatitis(Betændelse i huden), Stevens-Johnsons syndrom, toksisk epidermal nekrolyse
English: - if you are taking phenylbutazone, sodium salicylate, or aspirin.
Danish: - hvis du tager phenylbutazon, natriumsalicylat eller acetylsalicylsyre.
English: NAME OF THE MARKETING AUTHORISATION HOLDER [See Annex I - To be completed nationally] Name
Danish: NAVN PÅ INDEHAVEREN AF MARKEDSFØRINGSTILLADELSEN [Se bilag I - Skal udfyldes nationalt]
English: Hepatobiliary disorders very common hepatotoxicity not known alanine aminotransferase increased, alkaline phosphatase increased, aspartate amino transferase increased, bilirubin increased
Danish: Lever og galdeveje meget almindelig levertoksicitet ikke kendt forhøjet alaninaminotransferase, forhøjet alkalisk phosphatase, forhøjet aspartataminotransferase, forhøjet bilirubin
English: Non-Hodgkin's lymphoma
Danish: Non-Hodgkins lymfom
English: Other side effects experienced with VEPESID and associated names that are;
Danish: Andre bivirkninger erfaret med VEPESID og associerede navne, som er:
English: VEPESID and associated names should be terminated immediately, followed by the administration of pressor agents, corticosteroids, antihistamines, or volume expanders at the discretion of the physician.
Danish: og relaterede navne skal straks afbrydes og efterfølges af administration af pressorstoffer kortikosteroider, antihistaminer eller volumenekspandere efter lægens skøn.
English: SPECIAL STORAGE CONDITIONS [To be completed nationally]
Danish: SÆRLIGE OPBEVARINGSBETINGELSER [Skal udfyldes nationalt]
English: As etoposide may decrease male fertility, preservation of sperm may be considered for the purpose of later fatherhood (see section 4.6).
Danish: Da etoposid kan reducere fertilitet hos mænd, kan opbevaring af sperma overvejes med henblik på senere faderskab (se pkt.
English: Cardiac disorders common arrythmia, myocardial infarction
Danish: Hjerte almindelig arytmi, myokardieinfarkt
English: You must not breastfeed while you are taking VEPESID and associated names.
Danish: Du må ikke amme, mens du tager VEPESID og associerede navne.
English: Dose limiting bone marrow suppression is the most significant toxicity associated with VEPESID and associated names therapy.
Danish: Dosisbegrænsende knoglemarvssuppression er den vigtigste toksicitet forbundet med behandling med VEPESID og associerede navne.
English: Vascular disorders common hypertension not known haemorrhage
Danish: Vaskulære sygdomme almindelig hypertension ikke kendt blødning
English: VEPESID and associated names should only be administered and monitored under the supervision of a qualified physician experienced in the use of anti-neoplastic medicinal products.
Danish: VEPESID og relaterede navne må kun administreres og monitoreres under opsyn af en kvalificeret læge med erfaring i brugen af antineoplastiske lægemidler.
English: The exact reason why you have been prescribed VEPESID and associated names capsules is best discussed with your doctor.
Danish: Det er bedst at diskutere den specifikke grund til, at du har fået ordineret kapsler med VEPESID og associerede navne, med din læge.
English: • acid reflux
Danish: • gastroøsofageal reflux
English: Leucopenia and severe leucopenia (less than 1,000 cells/mm 91% and 3 to 17%, respectively, for etoposide.
Danish: Leukopeni og svær leukopeni (under 1.000 celler/mm3) blev observeret hos hhv. 60 % til 91 % og 3 % til 17 % for etoposid.
English: [See Annex 1 - To be completed nationally]
Danish: [Se bilag 1 - Skal udfyldes nationalt]
English: The capsule shell contain gelatin (E441), glycerol (85 per cent) (E422), red iron oxide (E172), sodium ethyl parahydroxybenzoate (E215), sodium propyl parahydroxybenzoate (E217) and titanium dioxide (E171).
Danish: Kapselskallen indeholder gelatine (E441), glycerol (85 procent) (E422), rød jernoxid (E172), ethylparahydroxybenzoat-natrium(E215), natriumpropyl-4-hydroxybenzoat (E217) og titandioxid (E171).
English: Doses subsequent to initial dose should be adjusted if neutrophil count less than 500 cells/mm occurs for more than 5 days or is associated with fever or infection, if platelet count less than 25,000 cells/mm occurs, if any grade 3 or 4 toxicity develops or if renal clearance is less than 50 ml/min.
Danish: Doser efter startdosen skal justeres, hvis neutrofiltallet er under 500 celler/mm i mere end 5 dage eller er forbundet med feber og infektion, hvis trombocyttallet er under 25.000 celler/mm3, hvis der udvikles toksicitet af grad 3 eller 4, eller hvis renal clearance er under 50 ml/min.
English: SUMMARY OF PRODUCT CHARACTERISTICS, LABELLING AND PACKAGE LEAFLET
Danish: PRODUKTRESUMÉ, ETIKETTERING OG INDLÆGSSEDDEL
English: General disorders and administration site conditions very common asthenia, malaise rare pyrexia
Danish: Almene symptomer og reaktioner på administrationsstedet meget almindelig asteni, utilpashed sjælden pyreksi
English: Blood and lymphatic system disorders very common anaemia , leucopenia, myelosuppression*, neutropenia, thrombocytopenia
Danish: Blod og lymfesystem meget almindelig anæmi, leukopeni, myelosuppression*, neutropeni, trombocytopeni
English: In the paragraphs below the incidences of adverse events, given as the mean percent, are derived from studies that utilized single agent VEPESID and associated names therapy.
Danish: I nedenstående paragraffer er forekomsten af bivirkninger, angivet ved den gennemsnitlige procent, afledt fra studier, hvori VEPESID og relaterede navne blev brugt som monoterapi.
English: Acute myeloid leukaemia
Danish: Akut myeloid leukæmi
English: VEPESID and associated names capsules contain sodium propyl parahydroxybenzoate and sodium ethyl parahydroxybenzoate which may cause allergic reactions (possibly delayed).
Danish: Kapsler af VEPESID og relaterede navneindeholder natriumpropyl-4-hydroxybenzoat og ethylparahydroxybenzoat-natrium, som kan forårsage allergiske reaktioner (muligvis forsinket).
English: Each 50 mg capsule, soft contains:
Danish: Hver 50 mg kapsel, blød indeholder:
English: The dose multiple (based on mg/m2 doses) for these findings at the no-observed adverse-effect-level in the preclinical studies were ≥ approximately
Danish: Dosismultiplikatoren (baseret på mg/m2 doser) for disse fund ved niveauet uden observerede bivirkninger var i de prækliniske studier ≥ cirka 0,05 gange sammenlignet med den højeste kliniske dosis.
English: In children, elevated SGPT levels are associated with reduced drug total body clearance.
Danish: Hos børn er forhøjede SGTP-niveauer forbundet med reduceret total clearance af lægemidlet fra kroppen.
English: Patients should not begin a new cycle of treatment with VEPESID and associated names if the neutrophil count is less than 1,500 cells/mm or the platelet count is less than 100,000 cells/mm unless caused by malignant disease.
Danish: Patienter må ikke begynde en ny behandlingscyklus med VEPESID og associerede navne, hvis neutrofiltallet er under 1.500 celler/mm eller trombocyttallet er under 100.000 celler/mm medmindre det er forårsaget af malign sygdom.
English: An alternative dosing of 50 mg/m body surface area taken each day for 2 to 3 weeks is sometimes used.
Danish: Der anvendes undertiden en alternativ dosering på 50 mg/m legemsoverflade taget dagligt i 2 til 3 uger.
English: Etoposide, therefore, is cleared by both renal and nonrenal processes, ie, metabolism and biliary excretion.
Danish: Etoposid elimineres derfor gennem både renale og ikke-renale processer, dvs. gennem stofskiftet og galden.
English: INSTRUCTIONS ON USE [To be completed nationally]
Danish: INSTRUKTIONER VEDRØRENDE ANVENDELSEN [Skal udfyldes nationalt]
English: Etoposide shows low penetration into the CSF.
Danish: Etoposid udviser lav penetrering i cerebrospinalvæsken.
English: The predominant macromolecular effect of etoposide seems to be the rupture of the double strand by an interaction with DNA
Danish: Den dominerende makromolekylære virkning af etoposid lader til at være ruptur af dobbeltstrengen ved en interaktion med DNA-topoisomerase II eller ved dannelse af frie radikaler.
English: Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.
Danish: Tag ikke VEPESID og relaterede navneefter den udløbsdato, der står på kartonen og blisterpakningen efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: • skin problems such as itching or rash Uncommon side effects (affecting between 1 in 100 and 1 in 1000 people)
Danish: • hudproblemer såsom kløe eller udslæt Ikke almindelige bivirkninger (påvirker mellem 1 ud af 100 og 1 ud af 1.000 personer)
English: Metabolic Complications
Danish: Stofskiftekomplikationer
English: Over the same dose range, the areas under the plasma concentration vs. time curves (AUC) and the maximum plasma concentration (Cmax) values increase linearly with dose.
Danish: I det samme dosisområde tiltager uafhængige af dosen i et dosisområde på 100 til 600 mg/m områderne under kurverne plasmakoncentration vs tid (AUC) og værdierne for den maksimale plasmakoncentration (Cmax) lineært i forhold til dosen.
English: • acute leukaemia
Danish: • akut leukæmi
English: Dosage should be modified to take into account the myelosuppressive effects of other drugs in the combination or the effects of prior radiotherapy or chemotherapy (see section 4.4), which may have compromised bone marrow reserve.
Danish: Dosering skal modificeres for at tage højde for de myelosuppressive virkninger af andre lægemidler i kombinationsbehandlingen, eller virkningen af tidligere stråleterapi eller kemoterapi (se pkt.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: {DD month YYYY}
Danish: DATO FOR FØRSTE MARKEDSFØRINGSTILLADELSE/FORNYELSE AF TILLADELSEN
English: Each 100 mg capsule, soft contains:
Danish: Hver 100 mg kapsel, blød indeholder:
English: Hodgkin's lymphoma
Danish: Hodgkins lymfom
English: Carcinogenic potential
Danish: Karcinogenicitet
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Danish: Overfølsomhed over for det aktive stof eller over for ét eller flere af hjælpestofferne anført i pkt.
English: The usual dose of VEPESID and associated names administered orally is 100 to 200 mg/m2/day on days 1 to 5 or 200 mg/m2/day on days 1, 3 and 5 every 3 to 4 weeks in combination with other drugs approved for use in the disease to be treated.
Danish: Den sædvanlige dosis VEPESID og associerede navne, som administreres oralt, er 100 til 200 mg/m2/dag på dag 1 til 5 eller 200 mg/m2/dag på dag 1, 3 og 5 hver 3. til 4. uge i kombination med andre lægemidler, der er godkendt til behandling af den aktuelle sygdom.
English: Contains sodium ethyl parahydroxybenzoate and sodium propyl parahydroxybenzoate (see leaflet for further information).
Danish: Indeholder ethylparahydroxybenzoat-natriumt og natriumpropyl-4-hydroxybenzoat (se indlægsseddel for yderligere information).
English: PHARMACEUTICAL FORM AND CONTENTS [To be completed nationally]
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) [Skal udfyldes nationalt]
English: If you take more VEPESID and associated names than you should If you take too many capsules go to your nearest hospital emergency department or tell your doctor immediately.
Danish: Hvis du har taget for mange kapsler, skal du straks fortælle det til din læge eller tage til nærmeste skadestue/akutklinik.
English: PHARMACEUTICAL FORM [To be completed nationally]
Danish: LÆGEMIDDELFORM [Skal udfyldes nationalt]
English: [See Annex I - To be completed nationally]
Danish: [Se bilag I - Skal udfyldes nationalt]
English: The usual dose of VEPESID and associated names administered orally is 100 to 200 mg/m2/day on days 1 to 5 or 200 mg/m2/day on days 1, 3 and 5 every 3 to 4 weeks.
Danish: Den sædvanlige dosis VEPESID og associerede navne, som administreres oralt, er 100 til 200 mg/m2/dag på dag 1 til 5 eller 200 mg/m2/dag på dag 1, 3 og 5 hver 3. til 4. uge.
English: Chronic toxicity
Danish: Kronisk toksicitet
English: Two dose-dependent responses are seen: At high concentrations (10 mcg/mL or more), cells entering mitosis are lysed; at low concentrations (0.3 to 10 mcg/mL), cells are inhibited from entering prophase.
Danish: Der ses to dosisafhængige reaktioner: Ved høje koncentrationer (10 mikrogram/ml eller mere) lyseres celler, som starter mitose.
English: Syncope, face oedema, swelling face, tongue oedema and swelling tongue can also occur with etoposide.
Danish: Synkope, ansigtsødem, hævet ansigt, tungeødem og hævet tunge kan også forekomme med etoposid.
English: Do not take VEPESID and associated names
Danish: Tag ikke VEPESID og associerede navne:
English: Myelosuppression (see section 4.4) with fatal outcome has been reported following administration of etoposide.
Danish: 4.4) med letal udgang er indberettet efter administration af etoposid.
English: Concomitant cisplatin therapy is associated with reduced total body clearance of etoposide.
Danish: Samtidig behandling med cisplatin er forbundet med reduceret total clearance af etoposid fra kroppen.
English: MARKETING AUTHORISATION NUMBER(S) [To be completed nationally]
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (NUMRE) [Skal udfyldes nationalt]
English: At decreased creatinine clearance of 15 to 50 mL/min a dose reduction by 25% is recommended.
Danish: Ved en reduceret kreatinin clearance på 15-50 ml/min.
English: Tumour lysis syndrome (sometimes fatal) has been reported following the use of etoposide in association with other chemotherapeutic drugs.
Danish: Tumorlysesyndrom (undertidenletalt) er blevet rapporteret efter brug af etoposid i forbindelse med andre kemoterapimidler.
English: The usual dose is 100 to 200 mg/m2 body surface area, daily for 5 days in a row or 200 mg/m2 body surface area on days 1, 3
Danish: Den almindelige dosis er 100 til 200 mg/m legemsoverflade, dagligt i 5 dage i træk eller 200 mg/m legemsoverflade på dag 1, 3 og 5.
English: 56% (45% of the dose was excreted as etoposide) and faecal recovery of radioactivity was 44% of the administered dose at 120 hours.
Danish: Efter intravenøs administration af 14C etoposid (100 til 124 mg/m2) var den gennemsnitlige genvinding af radioaktivitet i urinen 56 % (45 % af dosen blev udskilt som etoposid), mens genvinding af radioaktivitet i afføringen var 44 % af den administrerede dosis efter 120 timer.
English: Given the mutagenic potential of etoposide, an effective contraception is required for both male and female patients during treatment and up to 6 months after ending treatment.
Danish: Givet mutageniciteten af etoposid skal både mandlige og kvindelige patienter bruge sikker kontraception under behandling og i op til 6 måneder efter ophør af behandling.
English: Talk to your doctor or pharmacist before taking VEPESID and associated names
Danish: Kontakt lægen, før du tager VEPESID og associerede navne
English: DATE OF REVISION OF THE TEXT <{MM/YYYY}> <{DD/MM/YYYY}> <{DD month YYYY}> [To be completed nationally]
Danish: <{MM/ÅÅÅÅ}> <{DD/MM/ÅÅÅÅ}> <{DD måned ÅÅÅÅ}>
English: What you need to know before you take VEPESID and associated names
Danish: Det skal du vide, før du begynder at tage VEPESID og associerede navne
English: • damage to the liver (hepatotoxicity) Common side effects (affecting between 1 in 10 and 1 in 100 people)
Danish: • leverbeskadigelse (levertoksicitet) Almindelige bivirkninger (påvirker mellem 1 ud af 10 og 1 ud af 100 personer)
English: Tumour lysis syndrome (sometimes fatal) has been reported following the use of etoposide in association with other chemotherapeutic drugs (see section 4.4).
Danish: Tumorlysesyndrom (undertidenletalt) er indberettet efter brug af etoposid sammen med andre kemoterapimidler (se pkt.
English: If you forget to take VEPESID and associated names If you miss or forget to take a dose of this medicine, DO NOT WORRY - just take the next dose when it is due.
Danish: Hvis du glemmer eller springer en dosis af lægemidlet over, skal du IKKE VÆRE BEKYMRET.
English: GENERAL CLASSIFICATION FOR SUPPLY [To be completed nationally]
Danish: GENEREL KLASSIFIKATION FOR UDLEVERING [Skal udfyldes nationalt]
English: • loss of appetite
Danish: • appetittab
English: There is the potential for serious adverse reactions in nursing infants from VEPESID and associated names.
Danish: Der er risiko for alvorlige bivirkninger fra VEPESID og relaterede navne hos spædbørn, som ammes.
English: Note:
Danish: Bemærk!
English: Ovarian cancer
Danish: Kræft i æggestokkene
English: VEPESID and associated names is indicated for the treatment of platinum-resistant/refractory epithelial ovarian cancer in adults.
Danish: VEPESID og relaterede navneer indiceret til behandling af platinresistent/refraktær epitelial kræft i æggestokkene hos voksne.
English: Given the mutagenic potential of etoposide, an effective contraceptive is required for both male and female patients during treatment and up to 6 months after ending treatment (see section 4.4).
Danish: På baggrund af mutageniciteten af etoposid skal både mandlige og kvindelige patienter bruge sikker kontraceptionn under behandlingen og i op til 6 måneder efter behandlingsophør (se pkt.
English: Concomitant phenytoin therapy is associated with increased etoposide clearance and reduced efficacy, and other enzyme-inducing antiepileptic therapy may be associated with increased VEPESID and associated names clearance and reduced efficacy.
Danish: Anden enzyminduceret antiepileptisk behandling kan være forbundet med øget clearance af VEPESID og relaterede navne og reduceret effekt.
English: • generally feeling unwell (malaise)
Danish: • almindelig utilpashed (har det dårligt)
English: VEPESID and associated names (see Annex I) 50 mg capsule, soft VEPESID and associated names (see Annex I) 100 mg capsule, soft
Danish: VEPESID og relaterede navne(se bilag I) 50 mg kapsel, blød VEPESID og relaterede navne(se bilag I) 100 mg kapsel, blød
English: nausea and vomiting common diarrhoea, mucositis (including stomatitis and esophagitis)
Danish: Mave-tarm-kanalen meget almindelig mavesmerter, anoreksi, forstoppelse, kvalme og opkastning almindelig diarré, mucositis (herunder stomatitis og esophagitis)
English: Each capsule contains 100 mg etoposide
Danish: Hver kapsel indeholder 100 mg etoposid
English: The doses after the initial dose should be adjusted if neutrophil count is below 500 cells/mm for more than 5 days.
Danish: 4.4), som kan have kompromitteret knoglemarvsreserverne.Dosis, som følger efter den initiale dosis, skal justeres, hvis neutrofiltallet er under 500 celler/mm3 i mere end 5 dage.
English: Immune system disorders rare anaphylactic reactions not known angioedema, bronchospasm Metabolism and nutrition disorders not known tumour lysis syndrome
Danish: Immunsystemet sjælden anafylaktiske reaktioner ikke kendt angioødem, bronkospasme
English: Each soft capsule contains 100mg of etoposide
Danish: Hver blød kapsel indeholder 100 mg etoposid
English: Capsule shell
Danish: Kapselskal
English: • face and tongue swelling
Danish: • hævelse af ansigt og tunge
English: VEPESID and associated names (see Annex 1) 50 mg capsule, soft VEPESID and associated names (see Annex 1) 100 mg capsule, soft [See Annex I - To be completed nationally]
Danish: VEPESID og relaterede navne (se bilag 1) 50 mg kapsel, blød VEPESID og relaterede navne (se bilag 1) 100 mg kapsel, blød [Se bilag I - Skal udfyldes nationalt]
English: VEPESID and associated names should not be administered to patients with neutrophil counts less than 1,500 cell/mm3 or platelet counts less than 100,000cells/mm
Danish: VEPESID og relaterede navne må ikke administreres til patienter med neutrofiltal under 1.500 celler/mm eller trombocyttal under 100.000 celler/mm 3, medmindre det er forårsaget af malign sygdom.
English: A 100 mg oral dose would be comparable to a 75 mg intravenous dose; a 400 mg oral dose would be comparable to a 200 mg intravenous dose.
Danish: En oral dosis på 100 mg vil være sammenlignelig med en intravenøs dosis på 75 mg; en oral dosis på 400 mg vil være sammenlignelig med en intravenøs dosis på 200 mg. Variabiliteten i eksponering for den enkelte patient (dvs. mellem cyklusser) er større med oral administration end efter intravenøs administration (se punkt 4.4 og 5.2).
English: VEPESID and associated names contains sodium ethyl parahydroxybenzoate and sodium propyl parahydroxybenzoate
Danish: VEPESID og relaterede navneindeholder ethylparahydroxybenzoat-natrium og natriumpropyl-4hydroxybenzoat
English: What VEPESID and associated names is and what it is used for What you need to know before you take VEPESID and associated names How to take VEPESID and associated names Possible side effects
Danish: Det skal du vide, før du begynder at tage VEPESID og associerede navne Sådan skal du tage VEPESID og associerede navne Bivirkninger
English: Other medicines and VEPESID and associated names
Danish: Brug af anden medicin sammen med VEPESID og associerede navne
English: VEPESID and associated names contains sodium ethyl parahydroxybenzoate and sodium propyl parahydroxybenzoate.
Danish: VEPESID og relaterede navne indeholder ethylparahydroxybenzoat-natrium og natriumpropyl-4hydroxybenzoat.
English: Haematological Toxicity
Danish: Hæmatologisk toksicitet
English: • 1.22 mg of sodium ethyl parahydroxybenzoate (E215) and
Danish: • 1,22 mg ethylparahydroxybenzoat-natrium (E215) og
English: • increased liver enzymes
Danish: • forhøjede leverenzymer
English: • 0.93 mg of sodium ethyl parahydroxybenzoate (E215) and
Danish: • 0,93 mg ethylparahydroxybenzoat-natrium (E215) og
English: • convulsions (seizure)
Danish: • kramper (krampeanfald)
English: • 0.47 mg of sodium propyl parahydroxybenzoate (E217).
Danish: • 0,47 mg natriumpropyl-4-hydroxybenzoat (E217).
English: • flushing
Danish: • blussen
English: VEPESID and associated names 50mg Soft Capsules VEPESID and associated names 100mg Soft Capsules [See Annex I - To be completed nationally]
Danish: VEPESID og relaterede navne50 mg bløde kapsler VEPESID og relaterede navne100 mg bløde kapsler [Se bilag I - Skal udfyldes nationalt]
English: • 0.61 mg of sodium propyl parahydroxybenzoate (E217).
Danish: • 0,61 mg natriumpropyl-4-hydroxybenzoat (E217).
English: Do not open any <bottle> <blister> in which there is evidence of capsule leakage.
Danish: Du må ikke åbne<flasker> <blister>, hvis der er tegn på lækage fra kapsler.
English: Etoposide may cause adverse reactions that affect the ability to drive and use machines such as fatigue, somnolence,
Danish: Etoposid kan forårsage bivirkninger, som påvirker evnen til at føre motorkøretøj og betjene maskiner, såsom træthed, somnolens, kvalme, opkastning, kortikal blindhed, overfølsomhedsreaktioner med hypotension.