FrancophonIA/ELRC3.0 huggingface dataset:
English: Amoxicillin is not suitable for the treatment of some types of infection unless the pathogen is already documented and known to be susceptible or there is a very high likelihood that the pathogen would be suitable for treatment with amoxicillin (see section 5.1).
Slovenian: Amoksicilin ni primeren za zdravljenje nekaterih vrst okužb, razen če je patogen že dokumentiran in znano občutljiv, ali če obstaja zelo velika verjetnost, da bi bil patogen primeren za zdravljenje z amoksicilinom (glejte poglavje 5.1).
English: *Twice daily dosing regimens should only be considered when the dose is in the upper range.
Slovenian: * Sheme odmerjanja dvakrat na dan pridejo v poštev le, če je odmerek v zgornjem delu razpona.
English: 5Breakpoints relate only to non-meningitis isolates.
Slovenian: 5Mejne vrednosti veljajo le za nemeningitične izolate.
English: Other medicines may also be given at the same time.
Slovenian: Morda boste dobili tudi druga zdravila.
English: Indication+
Slovenian: Indikacija+
English: All doses are worked out depending on the child's body weight in kilograms.
Slovenian: Vsi odmerki so izračunani na osnovi otrokove telesne mase v kilogramih.
English: Magnesium stearate (E572)
Slovenian: magnezijev stearat (E572)
English: Parenteral:
Slovenian: Parenteralno:
English: This particularly applies when considering the treatment of patients with urinary tract infections and severe infections of the ear, nose and throat.
Slovenian: To še posebej velja v primeru zdravljenja bolnikov z okužbami sečil in hudimi okužbami ušesa, nosu ali žrela.
English: Using antibiotics carefully can help to reduce the chance of bacteria becoming resistant to them.
Slovenian: Skrbna uporaba antibiotikov lahko pomaga zmanjšati možnost, da bi bakterije postale odporne proti njim.
English: Take the medicine to show the doctor.
Slovenian: S seboj vzemite škatlo zdravila, da jo boste pokazali zdravniku.
English: The time above the minimum inhibitory concentration (T>MIC) is considered to be the major determinant of efficacy for amoxicillin.
Slovenian: Čas, ko koncentracija v serumu ostane nad minimalno inhibicijsko koncentracijo (t >MIK), velja kot glavna determinanta učinkovitosti amoksicilina.
English: See also anaemia below which might result in jaundice.
Slovenian: Glejte tudi o anemiji, spodaj, ki lahko povzroči zlatenico.
English: Do not take a double dose to make up for a forgotten dose.
Slovenian: • Ne vzemite dvojnega odmerka, da bi nadomestili izpuščeni odmerek.
English: Reproductive studies in animals have shown no effects on fertility.
Slovenian: Reproduktivne študije na živalih niso pokazale učinkov na plodnost.
English: Limited data on the use of amoxicillin during pregnancy in humans do not indicate an increased risk of congenital malformations.
Slovenian: Maloštevilni podatki o uporabi amoksicilina med nosečnostjo pri človeku ne kažejo povečanega tveganja prirojenih malformacij.
English: They are mainly associated with people having treatment over a long period, males and the elderly.
Slovenian: V glavnem se pojavijo pri ljudeh, ki se zdravijo daljše časovno obdobje, moških in starejših.
English: Amoxicillin may be used in pregnancy when the potential benefits outweigh the potential risks associated with treatment.
Slovenian: Amoksicilin se lahko uporablja v nosečnosti, ko možne koristi odtehtajo morebitna tveganja, povezana z zdravljenjem.
English: The doctor, nurse or pharmacist will make up the injection before use using an appropriate fluid (such as Water for Injections or an injection/infusion fluid).
Slovenian: - Zdravnik, medicinska sestra ali farmacevt bo pred uporabo pripravil raztopino za injiciranje z ustrezno tekočino (kot je voda za injiciranje ali tekočina za injiciranje/infundiranje).
English: Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity.
Slovenian: Študije na živalih ne kažejo na neposredne ali posredne škodljive vplive na reproduktivno toksičnost.
English: Amoxicillin is less stable in infusions containing carbohydrate.
Slovenian: Amoksicilin je manj stabilen v infuzijah, ki vsebujejo ogljikove hidrate.
English: What Amoxil is and what it is used for What you need to know before you take Amoxil How to take Amoxil
Slovenian: Kaj je zdravilo Amoxil in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Amoxil Kako jemati zdravilo Amoxil
English: Intravenous amoxicillin may be given in a range of different intravenous fluids.
Slovenian: Intravenski amoksicilin je mogoče dati v več različnih intravenskih tekočinah.
English: Reconstituted vials (for intravenous injection or before dilution for infusion), see section 6.6.
Slovenian: Rekonstituirane viale (za intravensko injekcijo ali pred redčenjem za infuzijo), glejte poglavje 6.6.
English: *Consideration should be given to the official treatment guidelines for each indication.
Slovenian: *Upoštevati je treba uradne smernice zdravljenja za vsako indikacijo.
English: Read the instructions on the label and if you do not understand anything ask your doctor or pharmacist to explain.
Slovenian: Preberite navodila na lekarniški signaturi in če česa ne razumete, prosite zdravnika ali farmacevta za pojasnilo.
English: Therapy can be started parenterally according to the dosing recommendations of the intravenous formulation and continued with an oral preparation.
Slovenian: Zdravljenje je mogoče začeti parenteralno v skladu s priporočili za odmerjanje za intravensko obliko in ga nadaljevati s peroralno obliko.
English: • Add the tablet to a glass of water and stir well until evenly mixed.
Slovenian: • Dodajte tableto v kozarec vode in dobro premešajte, dokler ni enakomerno premešano.
English: no adjustment necessary no adjustment necessary
Slovenian: prilagoditev ni potrebna prilagoditev ni potrebna
English: This is due to inflammation of blood vessel walls due to an allergic reaction.
Slovenian: To je posledica vnetja stene žil zaradi alergijske reakcije.
English: • Inactivation by bacterial beta-lactamases.
Slovenian: • Inaktivacija z bakterijskimi beta-laktamazami.
English: Species for which acquired resistance may be a problem Gram-negative aerobes:
Slovenian: Vrste pri katerih je lahko problem pridobljena odpornost Gramnegativni aerobi:
English: • serious liver side effects may occur.
Slovenian: • Lahko se pojavijo resni neželeni učinki na jetra.
English: The dose of Amoxil that is selected to treat an individual infection should take into account:
Slovenian: Odmerjanje Pri izbiri odmerka zdravila Amoxil za zdravljenje posamezne okužbe je treba upoštevati:
English: Amoxicillin is excreted into breast milk in small quantities with the possible risk of sensitisation.
Slovenian: Amoksicilin se izloča v materino mleko v majhnih količinah z možnim tveganjem za senzibilizacijo.
English: T 1/2 (h) AUC (µg.h/ml)
Slovenian: t 1/2 (ur) AUC (µg.ur/ml)
English: Enterococcus spp.3 Streptococcus groups A, B, C and G Note 4
Slovenian: Enterococcus spp.3 Streptokoki skupin A, B, C in G Opomba 4
English: Your doctor, pharmacist or nurse can give you more details.
Slovenian: Zdravnik, farmacevt ali medicinska sestra vam lahko dajo podrobnejša navodila.
English: Post-marketing Data Very rare
Slovenian: Podatki iz obdobja po pridobitvi dovoljenja za promet Zelo redki
English: Resistant >
Slovenian: Odporni >
English: The main mechanisms of resistance to amoxicillin are:
Slovenian: Mehanizmi odpornosti Glavna mehanizma odpornosti proti amoksicilinu sta:
English: Amoxil may be administered either by slow intravenous injection over a period of 3 to 4 minutes directly into a vein or via a drip tube or by infusion over 20 to 30 minutes.
Slovenian: Zdravilo Amoxil je treba uporabiti bodisi v počasni intravenski injekciji v trajanju od 3 do 4 minute neposredno v veno bodisi v kapalki ali infuziji v trajanju od 20 do 30 minut.
English: For intramuscular use after reconstitution.
Slovenian: Za intramuskularno uporabo po rekonstituciji.
English: Kidney problems If you have kidney problems the dose might be lower than the usual dose.
Slovenian: Če imate težave z ledvicami, je odmerek lahko nižji od običajnega odmerka.
English: This medicine should be used with caution in patients with phenylketonuria.
Slovenian: To zdravilo je treba uporabljati previdno pri bolnikih s fenilketonurijo.
English: Paying attention to the following advice will help prevent the emergence of resistant bacteria that could stop the antibiotic working.
Slovenian: Upoštevajte naslednje nasvete in to bo pomagalo preprečiti pojav odpornih bakterij, ki lahko onemogočijo delovanje antibiotika.
English: It results directly from the bactericidal activity of amoxicillin on the causative bacteria of Lyme disease, the spirochaete Borrelia burgdorferi.
Slovenian: Ta nastane neposredno zaradi baktericidnega delovanja amoksicilina na bakterijopovzročiteljico lymske borelioze, spiroheto Borrelia burgdorferi.
English: Children weighing 40 kg or more should be prescribed the adult dosage.
Slovenian: Otrokom, ki tehtajo 40 kg ali več, je treba predpisati odmerek za odrasle.
English: Liquid suspension
Slovenian: Tekoča suspenzija
English: Due to the high urinary concentrations of amoxicillin, false positive readings are common with chemical methods.
Slovenian: Zaradi visoke koncentracije amoksicilina v urinu so s kemičnimi metodami pogosti lažno pozitivni rezultati.
English: Shake until a suspension is formed.
Slovenian: Pretresite, da nastane suspenzija.
English: Reconstituted solutions of amoxicillin may be injected into the drip tubing over a period of 0.5 to 1 hour.
Slovenian: Rekonstituirano raztopino amoksicilina je mogoče injicirati v infuzijski sistem v trajanju od 0,5 do 1 ure.
English: Amoxicillin is susceptible to degradation by beta-lactamases produced by resistant bacteria and therefore the spectrum of activity of amoxicillin alone does not include organisms which produce these enzymes.
Slovenian: Amoksicilin je občutljiv za razgradnjo z betalaktamazami, ki jih proizvajajo odporne bakterije, in zato spekter delovanja samega amoksicilina ne zajema organizmov, ki izdelujejo te encime.
English: Talk to your doctor as soon as possible.
Slovenian: Nemudoma se posvetujte z zdravnikom.
English: • low number of cells involved with blood clotting
Slovenian: • majhno število celic, udeleženih v strjevanju krvi,
English: This can include a skin rash or swelling of the face or throat.
Slovenian: Ta lahko obsega izpuščaj na koži ali oteklost obraza ali žrela.
English: Amoxil may also be used in combination with other medicines to treat stomach ulcers.
Slovenian: Zdravilo Amoxil se lahko uporablja tudi v kombinaciji z drugimi zdravili za zdravljenje razjed na želodcu.
English: When administered directly into a muscle or a vein, it should be used immediately following reconstitution (usually this process takes about 5 minutes).
Slovenian: Če je zdravilo dano v mišico ali veno, ga je treba uporabiti takoj po rekonstituciji (običajno postopek traja 5
English: In vitro susceptibility of micro-organisms to Amoxicillin
Slovenian: In vitro občutljivost mikroorganizmov na amoksicilin
English: When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L
Slovenian: Če je tako, uporabite MIK mejno vrednost S ≤ 0,5 mg/l.
English: • Space the doses evenly during the day, at least 4 hours apart.
Slovenian: • Odmerke enakomerno razporedite čez dan s presledkom vsaj 4 ure.
English: The presence of amoxicillin may distort assay results for oestriol in pregnant women.
Slovenian: Prisotnost amoksicilina lahko zmoti rezultate preskusa za estriol pri nosečnicah.
English: + Consideration should be given to the official treatment guidelines for each indication.
Slovenian: + Upoštevati je treba uradne smernice zdravljenja za vsako indikacijo.
English: Amoxil Powder for Solution for Injection or Infusion is usually used for urgent treatment of severe infection or if patients cannot take Amoxil by mouth.
Slovenian: Zdravilo Amoxil prašek za raztopino za injiciranje ali infundiranje se običajno uporablja za nujno zdravljenje hudih okužb ali če bolniki ne morejo jemati zdravila Amoxil peroralno.
English: • Intravenous maximum single dose: 2 g by infusion or 1 g by bolus injection.
Slovenian: • Intravenski maksimalni enkratni odmerek: 2 g z infuzijo ali 1 g z bolusno injekcijo.
English: All solutions should be shaken vigorously before injection.
Slovenian: Vse raztopine je treba močno stresati pred injiciranjem.
English: • If you are taking medicines to help stop blood clots (such as warfarin), you may need extra blood tests.
Slovenian: • Če jemljete zdravila za preprečevanje krvnih strdkov (npr. varfarin), so lahko potrebne dodatne preiskave krvi.
English: The expiry date and storage instructions stated on the label are for the doctor, pharmacist or nurse's information.
Slovenian: Datum izteka roka uporabnosti zdravila in navodilo za shranjevanje na nalepki so informacije za zdravnika, farmacevta ali medicinsko sestro.
English: During the administration of high doses of amoxicillin, it is advisable to maintain adequate fluid intake and urinary output in order to reduce the possibility of amoxicillin crystalluria.
Slovenian: Med uporabo velikih odmerkov amoksicilina je priporočljivo vzdrževati ustrezen vnos tekočin in izločanje urina, da bi zmanjšali možnost amoksicilinske kristalurije.
English: • Maltodextrin is absorbed as glucose.
Slovenian: • Maltodekstrin se absorbira kot glukoza.
English: Therefore, it is important to consider this diagnosis in patients who present with diarrhoea during, or subsequent to, the administration of any antibiotics.
Slovenian: Zato je na to diagnozo treba pomisliti pri vseh bolnikih, ki med uporabo ali po uporabi kateregakoli antibiotika dobijo drisko.
English: All solutions should be shaken vigorously before injection and administered within 30 minutes of reconstitution.
Slovenian: Vse raztopine je treba močno stresati pred injiciranjem in aplicirati v 30 minutah po rekonstituciji.
English: 6Breakpoints are based on intravenous administration.
Slovenian: 6Mejne vrednosti temeljijo na intravenski uporabi.
English: 1.5 ml water for injections
Slovenian: 1,5 ml voda za injekcije
English: • The expected pathogens and their likely susceptibility to antibacterial agents (see section 4.4)
Slovenian: • pričakovane patogene in verjetnost njihove občutljivosti za protibakterijska zdravila (glejte poglavje
English: • Amoxil will be given as an injection or an infusion into a vein (intravenously) or muscle
Slovenian: • Zdravilo Amoxil boste dobili v obliki injekcije ali infuzije v veno (intravensko) ali v mišico
English: Shellac (E904) Titanium dioxide (E171)
Slovenian: šelak (E904) titanov dioksid (E171)
English: Intravenous solution Water for injection NaCl
Slovenian: Intravenska raztopina Voda za injekcije NaCl
English: Late stage (systemic involvement): 2 g every 8 hours
Slovenian: Pozni stadij (sistemska prizadetost): 2 g vsakih 8 ur
English: Other medicines and Amoxil
Slovenian: Druga zdravila in zdravilo Amoxil
English: Tetracyclines and other bacteriostatic drugs may interfere with the bactericidal effects of amoxicillin.
Slovenian: Tetraciklini in druga bakteriostatična zdravila lahko vplivajo na baktericidni učinek amoksicilina.
English: • Put the content of the sachet in 10 to 20 ml of water.
Slovenian: • Vsebino vrečice stresite v 10 do 20 ml vode.
English: Adults, elderly patients and children weighing 40 kg or more
Slovenian: Odrasli, starejši bolniki in otroci, ki tehtajo 40 kg ali več
English: How long will you need to take Amoxil for?
Slovenian: Kako dolgo boste morali jemati zdravilo Amoxil ?
English: However, for information about sodium in Amoxil, please see section 2.
Slovenian: Vendar pa za več informacij o natriju v zdravilu Amoxil glejte poglavje 2.
English: Amoxil is used to treat infections caused by bacteria in different parts of the body.
Slovenian: Zdravilo Amoxil se uporablja za zdravljenje bakterijskih okužb na različnih delih telesa.
English: Do not inject more than 1 g of amoxicillin at one time in adults.
Slovenian: Pri odraslih ne injicirajte več kot 1 g amoksicilina naenkrat.
English: Superficial tooth discolouration has been reported in children.
Slovenian: Pri otrocih je bilo opisano površinsko obarvanje zob.
English: • Aspartame (E951) is a source of phenylalanine.
Slovenian: • Aspartam (E951) je vir fenilalanina.
English: • Make sure you drink plenty of fluids while having Amoxil.
Slovenian: • Poskrbite, da boste med zdravljenjem z zdravilom Amoxil zaužili dovolj tekočine.
English: • Bacteremia that occurs in association with, or is suspected to be associated with, any of the infections listed above
Slovenian: • bakteriemija, ki se pojavi v povezavi z, ali obstaja sum, da je povezana s katero koli od zgoraj navedenih okužb
English: This reaction requires amoxicillin discontinuation and contra-indicates any subsequent administration.
Slovenian: Ta reakcija zahteva prenehanje uporabe amoksicilina in pomeni kontraindikacijo za vsako poznejšo uporabo.
English: If you forget to take Amoxil
Slovenian: Če ste pozabili vzeti zdravilo Amoxil
English: Elevated serum and urinary levels of amoxicillin are likely to affect certain laboratory tests.
Slovenian: Verjetno je, da zvišana koncentracija amoksicilina v serumu in urinu vpliva na določene laboratorijske preiskave.
English: • Urine tests (glucose) or blood tests for liver function
Slovenian: • preiskavo urina (za glukozo) ali preiskavo krvi za jetrno funkcijo,
English: Parenteral: Lidocaine or benzyl alcohol may be used only when administering amoxicillin by the intramuscular route.
Slovenian: Parenteralno: Lidokain ali benzilalkohol se lahko uporabljata le pri dajanju amoksicilina intramuskularno.
English: If you take Amoxil for a long time, your doctor may perform additional tests to check your kidneys, liver and blood are working normally.
Slovenian: Če jemljete zdravilo Amoxil dlje časa, lahko zdravnik opravi dodatne preskuse, da preveri, ali ledvice, jetra in kri delujejo normalno.
English: Amoxicillin is a semisynthetic penicillin (beta-lactam antibiotic) that inhibits one or more enzymes (often referred to as penicillin-binding proteins, PBPs) in the biosynthetic pathway of bacterial peptidoglycan, which is an integral structural component of the bacterial cell wall.
Slovenian: Način delovanja Amoksicilin je polsintezni penicilin (betalaktamski antibiotik), ki zavira enega ali več encimov (penicilin vežočih beljakovin, PBP - penicillin-binding proteins) v biosintezni poti bakterijskega peptidoglikana, ki je integralna sestavina zgradbe bakterijske celične stene.
English: Following oral administration, amoxicillin is approximately 70% bioavailable.
Slovenian: Po peroralni uporabi je biološka uporabnost amoksicilina približno 70 %.
English: Amoxil should not be mixed with blood products, other proteinaceous fluids such as protein hydrolysates or with intravenous lipid emulsions.
Slovenian: Zdravilo Amoxil se ne sme mešati s krvnimi pripravki, drugimi tekočinami, ki vsebujejo proteine, npr. proteinskimi hidrolizati, ali z lipidnimi emulzijami za intravensko uporabo.
English: Appropriate monitoring should be undertaken when anticoagulants are prescribed concomitantly.
Slovenian: Med sočasno uporabo antikoagulantov so potrebne ustrezne kontrole.
English: In patients with reduced urine output, crystalluria has been observed very rarely, predominantly with parenteral therapy.
Slovenian: Pri bolnikih z zmanjšanim izločanjem urina so v redkih primerih opažali kristalurijo, predvsem med parenteralnim zdravljenjem.
English: 1Wild type Enterobacteriaceae are categorised as susceptible to aminopenicillins.
Slovenian: 1Enterobacteriaceae divjega tipa so uvrščene med občutljive za aminopeniciline.
English: Put the content of the sachet in 10 to 20 ml of water.
Slovenian: Stresite vsebino vrečice v 10 - 20 ml vode.
English: Concomitant use of probenecid may result in increased and prolonged blood levels of amoxicillin.
Slovenian: Sočasna uporaba probenecida lahko povzroči povečanje in podaljšanje koncentracije amoksicilina v krvi.
English: These may be associated with fever, headaches and body aches
Slovenian: Ti znaki so lahko povezani z vročino, glavoboli in bolečino po telesu.
English: Patients with rare glucose-galactose malabsorption should not take this medicine.
Slovenian: Bolniki z redko glukozno-galaktozno malabsorpcijo ne smejo jemati tega zdravila.
English: Contents of the pack and other information What Amoxil contains
Slovenian: Vsebina pakiranja in dodatne informacije Kaj vsebuje zdravilo Amoxil
English: Amoxil is indicated for the treatment of the following infections in adults and children (see sections 4.2, 4.4 and 5.1):
Slovenian: 4.1 Terapevtske indikacije Zdravilo Amoxil je indicirano za zdravljenje naslednjih okužb pri odraslih in otrocih (glejte poglavja 4.2, 4.4 in 5.1): Peroralne indikacije
English: Latvia - Amoxil 500 mg kapsulas Lithuania - Amoxil
Slovenian: Latvija - Amoxil 500 mg kapsulas Litva - Amoxil
English: Type I) and a tamper evident sealing ring.
Slovenian: tip I) in zaščitnim tesnilnim obročkom.
English: The duration of therapy should be determined by the type of infection and the response of the patient, and should generally be as short as possible.
Slovenian: Trajanje zdravljenja, ki bi praviloma moralo biti najkrajše možno, je treba določiti glede na vrsto okužbe in bolnikov odziv.
English: Important information about excipients
Slovenian: Pomembne informacije o pomožnih snoveh
English: Invert and shake bottle to loosen powder.
Slovenian: Obrnite in pretresite steklenico, da zrahljate prašek.
English: Neonates ≥ 4kg and infants up to 3 months
Slovenian: Novorojenčki ≥ 4kg in dojenčki do 3 mesecev
English: • Stomach ulcers: one 750 mg or one 1 g dose twice a day for 7 days with other antibiotics and medicines to treat stomach ulcers.
Slovenian: • Želodčne razjede: En odmerek 750 mg ali en odmerek 1 g dvakrat na dan 7 dni, skupaj z drugimi antibiotiki in zdravili za zdravljenje razjed na želodcu.
English: Bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed in section 4.1
Slovenian: Bakteriemija, ki se pojavi v povezavi z, ali obstaja sum, da je povezana s katero koli od okužb, navedenih v poglavju 4.1.
English: Approximately 60 to 70% of the amoxicillin is excreted unchanged in urine during the first 6 hours after administration of a single 250 mg or 500 dose of amoxicillin.
Slovenian: Približno 60 do 70 % amoksicilina se izloči nespremenjenega v urinu v prvih 6 urah po uporabi enega 250 mg ali 500 mg odmerka amoksicilina.
English: Acute otitis media
Slovenian: Akutni otitis media
English: If an allergic reaction occurs, amoxicillin therapy must be discontinued and appropriate alternative therapy instituted.
Slovenian: Če se pojavi alergijska reakcija, je treba zdravljenje z amoksicilinom prekiniti in uvesti ustrezno drugo zdravljenje.
English: 2.5 ml water for injections or 5.1 ml benzyl alcohol solution
Slovenian: 2,5 ml voda za injekcije ali 5,1 ml benzilalkohol raztopina
English: Once made up, the suspension should be used within 14 days.
Slovenian: Pripravljena suspenzija je uporabna 14 dni.
English: • a delayed allergic reaction can occur usually 7 to 12 days after having Amoxil, some signs include: rashes, fever, joint pains and enlargement of the lymph nodes especially under the arms
Slovenian: • Zakasnela alergijska reakcija se pojavi običajno 7 do 12 dni po jemanju zdravila Amoxil; nekateri znaki vključujejo: izpuščaje, vročino, bolečine v sklepih in povečanje bezgavk, zlasti pod pazduhami.
English: Commonly Susceptible Species
Slovenian: Pogosto občutljive vrste
English: Add the tablet to a glass of water and stir well until evenly mixed.
Slovenian: Tableto dajte v kozarec vode in mešajte, dokler ni enakomerno premešana.
English: The score lines are only to facilitate breaking for ease of swallowing and not to divide into equal doses.
Slovenian: Razdelilna zareza je namenjena le delitvi tablete za lažje požiranje in ne delitvi na dva enaka odmerka.
English: 500 mg every 12 hours
Slovenian: 500 mg vsakih 12 ur
English: In the range 250 to 3000 mg the bioavailability is linear in proportion to dose (measured as Cmax and AUC).
Slovenian: *mediana (razpon) V razponu 250 do 3000 mg je biološka uporabnost linearna glede na odmerek (merjena kot Cmax in AUC).