FrancophonIA/ELRC3.0 huggingface dataset:
English: No profound binding to plasma proteins, except circulating insulin antibodies (if present) has been observed.
Croatian: Nije opaženo znatnije vezanje za proteine u plazmi, osim za inzulinska protutijela u cirkulaciji (ako su prisutna).
English: ► Every time you use a new Actraphane Penfill (before you put the cartridge into the insulin delivery system).
Croatian: ► Svaki puta kada koristite novi Actraphane Penfill (prije nego što uložak stavite u pomagalo za primjenu inzulina)
English: • Severe hypoglycaemic episodes, where the patient has become unconscious, can be treated with glucagon (0.5 to 1 mg) given intramuscularly or subcutaneously by a trained person, or with glucose given intravenously by a healthcare professional.
Croatian: • Teške epizode hipoglikemije, u kojima bolesnik ostane bez svijesti, mogu se liječiti glukagonom (0,5 do 1 mg) koji intramuskularno ili supkutano daje osoba upoznata s načinom primjene, ili glukozom koju intravenski daje zdravstveni radnik.
English: If there are less than 12 units left, use a new FlexPen.
Croatian: Ako je ostalo manje od 12 jedinica, upotrijebite novi FlexPen.
English: Actraphane is used to reduce the high blood sugar level in patients with diabetes mellitus (diabetes).
Croatian: Actraphane se koristi za snižavanje visoke razine šećera u krvi u bolesnika s dijabetesom (šećernom bolešću).
English: If any of these apply, do not use Actraphane.
Croatian: Ako se nešto od toga odnosi na Vas, nemojte primjenjivati Actraphane.
English: This process is influenced by several factors (e.g. insulin dose, injection route and site, thickness of subcutaneous fat, type of diabetes).
Croatian: Na ovaj proces utječe nekoliko faktora (primjerice, doza inzulina, put i mjesto injiciranja, debljina potkožnog masnog tkiva, tip šećerne bolesti).
English: This could lead to very high blood sugar (severe hyperglycaemia) and ketoacidosis.
Croatian: To može dovesti do vrlo visoke razine šećera u krvi (teške hiperglikemije) i ketoacidoze.
English: If you have reduced kidney or liver function, or if you are above 65 years of age, you need to check your blood sugar more regularly and discuss changes in your insulin dose with your doctor.
Croatian: Ako imate smanjenu funkciju bubrega ili jetre, ili ste stariji od 65 godina, trebate češće kontrolirati šećer u krvi i s liječnikom razgovarati o promjenama doze inzulina.
English: Injection into a lifted skin fold minimises the risk of unintended intramuscular injection.
Croatian: Injekcija u podignut nabor kože umanjuje rizik od nehotične intramuskularne injekcije.
English: Insulin medicinal products should only be added to compounds with which it is known to be compatible.
Croatian: Inzulinski pripravci se smiju dodavati samo onim sastojcima za koje se zna da su im kompatibilni.
English: Changes in strength, brand (manufacturer), type, origin (animal insulin, human insulin or insulin analogue) and/or method of manufacture (recombinant DNA versus animal source insulin) may result in a need for a change in dose.
Croatian: Promjene u jačini, nazivu inzulina (proizvođač), vrsti, podrijetlu (životinjski inzulin, humani inzulin ili inzulinski analog) i/ili načinu proizvodnje (rekombinantna DNK u odnosu na inzulin životinjskog podrijetla) mogu rezultirati potrebom za promjenom doze.
English: It is therefore recommended that the diabetic patient always carries sugar-containing products.
Croatian: Stoga se bolesniku koji ima šećernu bolest preporučuje da sa sobom uvijek nosi proizvode koji sadrže šećer.
English: Animal reproduction studies with human insulin have not revealed any adverse effects on fertility.
Croatian: Ispitivanja reprodukcije na životinjama nisu otkrila štetne učinke humanog inzulina na plodnost.
English: ► If you are treated with Actraphane Penfill and another insulin Penfill cartridge, you should use two insulin delivery systems, one for each type of insulin.
Croatian: ► Ako se liječite lijekom Actraphane Penfill i još jednim inzulinom u Penfill ulošku, morate koristiti dva pomagala za primjenu inzulina, po jedan za svaku vrstu inzulina.
English: • Inject too much insulin.
Croatian: • injicirate previše inzulina.
English: Needle (example)
Croatian: Igla (primjer)
English: rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000); not known (cannot be estimated from the available data).
Croatian: Za učestalost pojavljivanja korištena je sljedeća kategorizacija: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000); nepoznato (ne može se procijeniti na temelju dostupnih podataka).
English: Your insulin dose may need to be changed during pregnancy and after delivery.
Croatian: Možda će biti potrebno promijeniti dozu inzulina tijekom trudnoće i nakon poroda.
English: If you notice your skin pitting or thickening at the injection site, tell your doctor or nurse.
Croatian: Ako opazite da Vam se na koži javljaju ulegnuća ili zadebljanja na mjestu injiciranja, obavijestite o tome svog liječnika ili medicinsku sestru.
English: If the dose selector stops before it returns to 0, the full dose has not been delivered, which may result in too high blood sugar level.
Croatian: Ako se izbornik doze zaustavi prije nego što dođe do 0, nije primijenjena cijela doza, zbog čega bi razina šećera u krvi mogla postati previsoka.
English: What to do if you experience high blood sugar: ► If you get any of the above signs: test your blood sugar level, test your urine for ketones if you can, then seek medical advice immediately.
Croatian: Što učiniti ako osjetite visoku razinu šećera u krvi: ► Ako primijetite neki od gore navedenih znakova, izmjerite razinu šećera u krvi i ako možete, provjerite ketone u mokraći, a zatim odmah zatražite medicinski savjet.
English: * see Description of selected adverse reactions
Croatian: *vidjeti Opis odabranih nuspojava
English: An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.
Croatian: Unutar 30 minuta nakon injekcije treba uslijediti obrok ili međuobrok koji sadrži ugljikohidrate.
English: See also Serious allergic reactions above.
Croatian: Pogledajte i Ozbiljna alergijska reakcija u prethodnom odjeljku.
English: • Sympathomimetics (such as epinephrine [adrenaline], salbutamol or terbutaline used to treat asthma)
Croatian: • simpatomimetike (poput epinefrina [adrenalina], salbutamola ili terbutalina, koji se koriste za liječenje astme)
English: • Repeat this movement at least 10 times before each injection.
Croatian: • Ponovite te kretnje najmanje 10 puta prije svake injekcije.
English: - The active substance is human insulin.
Croatian: - Djelatna tvar je humani inzulin.
English: What to do if you experience low blood sugar: ► If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice).
Croatian: Što učiniti ako osjetite nisku razinu šećera u krvi: ► Ako osjetite nisku razinu šećera u krvi, uzmite tablete glukoze ili pojedite neki međuobrok bogat šećerom (primjerice, slatkiše, kekse, voćni sok).
English: Very rare side effects
Croatian: Vrlo rijetke nuspojave
English: Actraphane Penfill is accompanied by a package leaflet with detailed instructions for use to be followed.
Croatian: Penfill priložena je Uputa o lijeku s detaljnim naputcima za primjenu koje treba slijediti.
English: Check that the dose selector is set at 0.
Croatian: Provjerite je li izbornik doze postavljen na 0.
English: • Beta-blockers (used to treat high blood pressure)
Croatian: • beta-blokatore (koriste se za liječenje visokog krvnog tlaka)
English: Do not refill your FlexPen.
Croatian: Nemojte ponovno puniti FlexPen.
English: Before opening: Store in a refrigerator at 2°C - 8°C.
Croatian: Prije otvaranja: čuvati u hladnjaku na temperaturi od 2°C - 8°C.
English: • Sulfonamides (used to treat infections).
Croatian: • sulfonamide (koriste se za liječenje infekcija).
English: Changing the site with each injection may help to reduce the risk of developing such skin changes.
Croatian: Promjena mjesta injiciranja kod svake injekcije može pomoći umanjiti rizik od takvih promjena na koži.
English: Omission of a meal or unplanned strenuous physical exercise may lead to hypoglycaemia.
Croatian: Izostavljanje obroka ili neplanirana naporna tjelovježba mogu dovesti do hipoglikemije.
English: Resuspending is easier when the insulin has reached room temperature.
Croatian: Miješanje je lakše ako je inzulin dosegnuo sobnu temperaturu.
English: If you suspect that the cartridge is damaged, take it back to your supplier.
Croatian: Ako sumnjate da je uložak oštećen, vratite ga u ljekarnu.
English: Before opening: Store in a refrigerator.
Croatian: Prije otvaranja: čuvati u hladnjaku.
English: Summary of serious and very common side effects
Croatian: Sažetak ozbiljnih i vrlo čestih nuspojava
English: Other medicines and Actraphane
Croatian: Drugi lijekovi i Actraphane
English: If the combination is used, patients should be observed for signs and symptoms of heart failure, weight gain and oedema.
Croatian: U slučaju primjene ove kombinacije, u bolesnika treba pratiti znakove i simptome zatajivanja srca, porasta tjelesne težine i edema.
English: Inadequate dosing or discontinuation of treatment, especially in type 1 diabetes, may lead to hyperglycaemia and diabetic ketoacidosis.
Croatian: Neodgovarajuće doziranje ili prekid liječenja, posebice u šećernoj bolesti tipa 1, mogu dovesti do hiperglikemije i dijabetičke ketoacidoze.
English: The terminal half-life is determined by the rate of absorption from the subcutaneous tissue.
Croatian: Terminalni poluvijek određen je brzinom apsorpcije iz potkožnog tkiva.
English: Never try to put the inner needle cap back on the needle.
Croatian: Nikada nemojte pokušati vratiti unutarnji zatvarač na iglu.
English: If your blood sugar is low or high, it might affect your concentration and ability to react and therefore also your ability to drive or operate a machine. Bear in mind that you could endanger yourself or others.
Croatian: Ako je razina šećera u krvi niska ili visoka, to može utjecati na koncentraciju i sposobnost reagiranja pa time i na sposobnost vožnje i rukovanja strojevima.
English: In case of hypoglycaemia or if hypoglycaemia is suspected, Actraphane must not be injected.
Croatian: U slučaju hipoglikemije ili sumnje na hipoglikemiju Actraphane se ne smije injicirati.
English: The adverse reactions listed below are based on clinical trial data and classified according to MedDRA frequency and System Organ Class.
Croatian: Dolje navedene nuspojave temelje se na podacima iz kliničkih ispitivanja i prikazane su prema MedDRA učestalosti i klasifikaciji organskih sustava.
English: Do not soak it, wash or lubricate it as it may damage the pen.
Croatian: Nemojte je namakati, prati niti podmazivati jer to može oštetiti brizgalicu.
English: • Oral contraceptives (birth control pills)
Croatian: • oralne kontraceptive (tablete za sprječavanje začeća)
English: Swollen joints: When you start taking insulin, water retention may cause swelling around your ankles and other joints.
Croatian: Otečeni zglobovi: Kad počnete primjenjivati inzulin, nakupljanje vode može uzrokovati oticanje gležnjeva i drugih zglobova.
English: ► If FlexPen is dropped, damaged or crushed.
Croatian: ► ako je FlexPen pao, ako je oštećen ili razbijen.
English: ► If InnoLet is dropped, damaged or crushed.
Croatian: ► ako je InnoLet pao, ako je oštećen ili razbijen.
English: If you do not treat it, this could lead to diabetic coma and eventually death.
Croatian: Ako se ne liječi, to može dovesti do dijabetičke kome i u konačnici do smrti.
English: Diabetic retinopathy (an eye disease related to diabetes which can lead to loss of vision): If you have diabetic retinopathy and your blood sugar level improves very fast, the retinopathy may get worse.
Croatian: Dijabetička retinopatija (bolest očiju povezana sa šećernom bolešću koja može dovesti do gubitka vida): Ako imate dijabetičku retinopatiju, a razina šećera u krvi se vrlo brzo popravlja, retinopatija se može pogoršati.
English: You cannot select a dose larger than the number of units left in the cartridge.
Croatian: Ne možete odabrati veću dozu od broja jedinica koje su preostale u ulošku.
English: Your FlexPen must be handled with care.
Croatian: Brizgalicom FlexPen morate rukovati oprezno.
English: Close glucose monitoring is recommended during the transfer and in the initial weeks thereafter (see section 4.4).
Croatian: Tijekom prijelaza i u prvim tjednima nakon toga preporučuje se pomno pratiti razine glukoze (vidjeti dio 4.4).
English: Be careful not to bend or damage the needle before use.
Croatian: Pazite da ne savijete ili oštetite iglu prije uporabe.
English: Intensification of insulin therapy with abrupt improvement in glycaemic control may be associated with temporary worsening of diabetic retinopathy, while long-term improved glycaemic control decreases the risk of progression of diabetic retinopathy.
Croatian: Intenziviranje terapije inzulinom s naglim poboljšanjem regulacije glikemije može biti povezano s privremenim pogoršanjem dijabetičke retinopatije, dok dugoročno poboljšanje regulacije glikemije smanjuje rizik napredovanja dijabetičke retinopatije.
English: Concomitant illness, especially infections and feverish conditions, usually increases the patient's insulin requirement.
Croatian: Popratne bolesti, posebice infekcije i stanja praćena vrućicom, obično povećavaju bolesnikovu potrebu za inzulinom.
English: It is a biphasic formulation containing both fast-acting and long-acting insulin.
Croatian: To je bifazična formulacija koja sadrži i brzodjelujući i dugodjelujući inzulin.
English: • Have not injected enough insulin.
Croatian: • niste injicirali dovoljno inzulina.
English: • Let the insulin reach room temperature before you use it.
Croatian: • Pustite da inzulin dosegne sobnu temperaturu prije nego što ćete ga upotrijebiti.
English: Do not use this medicinal product if you notice that the resuspended liquid is not uniformly white and cloudy.
Croatian: Ovaj lijek se ne smije upotrijebiti ako primijetite da resuspendirana tekućina nije jednoliko bijela i zamućena.
English: Caregivers must be very careful when handling used needles - to reduce the risk of needle sticks and cross-infection.
Croatian: Osobe koje skrbe za bolesnika moraju biti vrlo oprezne pri rukovanju rabljenim iglama kako bi se smanjio rizik od uboda iglom i prijenosa infekcije.
English: A number of cleavage (hydrolysis) sites on the human insulin molecule have been proposed; none of the metabolites formed following the cleavage are active.
Croatian: molekule humanog inzulina; niti jedan od metabolita nastalih nakon cijepanja nije aktivan.
English: It must be handled with care.
Croatian: Morate njime rukovati oprezno.
English: Dose scale
Croatian: Skala doze
English: • Make sure not to block the dose selector while injecting, as the dose selector must be allowed to return to 0 when you press the push-button.
Croatian: • Pazite da tijekom injiciranja ne blokirate izbornik doze, jer je neophodno da se on može vratiti na 0 kad pritisnete potisni gumb.
English: This reduces the risk of contamination, infection,
Croatian: Time se smanjuje rizik od onečišćenja,
English: • Angiotensin converting enzyme (ACE) inhibitors (used to treat certain heart conditions or high blood pressure)
Croatian: • inhibitore angiotenzin konvertirajućeg enzima (ACE inhibitore) (koriste se za liječenje nekih srčanih poremećaja ili visokog krvnog tlaka)
English: Human insulin is reported to be degraded by insulin protease or insulin-degrading enzymes and possibly protein disulfide isomerase.
Croatian: Opisano je da se humani inzulin razgrađuje inzulinskom proteazom ili enzimima koji razgrađuju inzulin, a možda i proteinskom disulfid-izomerazom.
English: If not, talk to your doctor.
Croatian: Ako ne nestane, obratite se svom liječniku.
English: ► Keep the needle under your skin for at least 6 seconds.
Croatian: Zadržite iglu pod kožom najmanje 6 sekundi.
English: Actraphane can be used during pregnancy.
Croatian: Actraphane se može koristiti u trudnoći.
English: 2 units selected
Croatian: odabrane 2 jedinice
English: ► If the protective cap is loose or missing.
Croatian: ► ako zaštitni zatvarač ne stoji čvrsto ili nedostaje.
English: Fast improvement in blood glucose control may be associated with acute painful neuropathy, which is usually reversible.
Croatian: Naglo poboljšanje regulacije glikemije može biti povezano s akutnom bolnom neuropatijom, što je obično prolazno.
English: • Be careful not to bend or damage the needle before use.
Croatian: • Pazite da ne savijete ili oštetite iglu prije uporabe.
English: After you have resuspended the insulin, complete all the following steps of injection without delay.
Croatian: Nakon što ste izmiješali inzulin, bez odgađanja dovršite sve preostale korake injiciranja.
English: You can select doses from 1 to 60 units in increments of 1 unit.
Croatian: jedinicu mogu se birati doze u rasponu od 1 do 60 jedinica.
English: You may recover more quickly from unconsciousness with an injection of the hormone glucagon by someone who knows how to use it.
Croatian: Možete se brže probuditi iz nesvjestice ako Vam netko tko ga zna primijeniti injicira hormon glukagon.
English: Consult your doctor: ► If you have trouble with your kidneys or liver, or with your adrenal, pituitary or thyroid glands.
Croatian: Posavjetujte se sa svojim liječnikom: ► ako imate problema s bubrezima ili jetrom, ili s nadbubrežnom žlijezdom, hipofizom ili štitnjačom.
English: The dose can be corrected either up or down by turning the dose selector in either direction until the correct dose lines up with the pointer.
Croatian: Dozu možete ispraviti i prema većoj i prema manjoj dozi zakretanjem izbornika doze u jednom ili drugom smjeru, sve dok ispravna doza ne bude u ravnini s pokazivačem.
English: Eat a meal or snack containing carbohydrates within 30 minutes of the injection to avoid low blood sugar.
Croatian: Unutar 30 minuta od injiciranja pojedite obrok ili međuobrok koji sadrži ugljikohidrate da izbjegnete nisku razinu šećera u krvi.
English: Actraphane can be used in elderly patients.
Croatian: Actraphane se može koristiti u starijih bolesnika.
English: Always keep your InnoLet and needles out of sight and reach of others, especially children.
Croatian: Uvijek čuvajte svoju brizgalicu i igle izvan pogleda i dohvata drugih osoba, osobito djece.
English: ► When the symptoms of low blood sugar have disappeared or when your blood sugar level is stabilised, continue insulin treatment as usual.
Croatian: ► Kad simptomi niske razine šećera u krvi nestanu ili Vam se stabilizira razina šećera u krvi, nastavite liječenje inzulinom kao obično.
English: Actraphane is administered subcutaneously by injection in the thigh, the abdominal wall, the gluteal region or the deltoid region.
Croatian: Actraphane se primjenjuje supkutanom injekcijom u bedro, trbušnu stijenku, glutealno ili deltoidno područje.
English: If it is not in perfect condition when you get the vial, return the vial to your supplier.
Croatian: Ako on nije u besprijekornom stanju kad dobijete bočicu, vratite bočicu u ljekarnu.
English: • Hold your InnoLet with the needle upwards and tap the cartridge gently with your finger a few times (picture 1C) to make any air bubbles collect at the top of the cartridge.
Croatian: • InnoLet držite iglom okrenutom prema gore te nekoliko puta lagano kucnite prstom po ulošku (slika 1C), kako bi se mjehurići zraka skupili na vrhu uloška.
English: ► If you drink alcohol, your need for insulin may change as your blood sugar level may either rise or fall.
Croatian: Ako konzumirate alkohol, Vaša potreba za inzulinom može se promijeniti jer Vam razina šećera u krvi može ili porasti ili pasti.
English: ► If you have such low blood sugar that it makes you pass out, if you have had the need for an injection of glucagon, or if you have experienced many incidents of low blood sugar, talk to a doctor.
Croatian: ► Ako imate tako nisku razinu šećera u krvi da se onesvijestite, ako Vam je bila potrebna injekcija glukagona ili ako često imate nisku razinu šećera u krvi, obratite se svom liječniku.
English: Very common - Hypoglycaemia*
Croatian: Vrlo često - hipoglikemija*
English: If a drop of insulin still does not appear, the pen is defective, and you must use a new one.
Croatian: Ako se i nakon toga kapljica inzulina ne pojavi, brizgalica je neispravna i morate upotrijebiti novu.
English: Water for injections
Croatian: Protaminsulfat Voda za injekcije
English: • Move the pen up and down between positions A and B and back so that the glass ball moves from one end of the cartridge to the other (picture 1A) at least 20 times.
Croatian: • Pomičite brizgalicu gore - dolje između položaja A i B, tako da se staklena kuglica kreće s jednog kraja uloška na drugi (slika 1A) najmanje 20 puta.
English: Glass ball
Croatian: Staklena kuglica
English: • Deliver the dose by pressing the push-button fully down (picture 3).
Croatian: • Injicirajte dozu tako da potisni gumb pritisnete do kraja (slika 3).
English: The occurrence of generalised hypersensitivity reactions (including generalised skin rash, itching, sweating, gastrointestinal upset, angioneurotic oedema, difficulty in breathing, palpitation and reduction in blood pressure) is very rare but can potentially be life threatening.
Croatian: Generalizirane reakcije preosjetljivosti (uključujući generalizirani kožni osip, svrbež, znojenje, gastrointestinalne poremećaje, angioneurotski edem, poteškoće s disanjem, palpitacije i pad krvnog tlaka) javljaju se vrlo rijetko, ali mogu biti opasne po život.
English: Continuous rotation of the injection site within a given area reduces the risk of developing these reactions.
Croatian: Neprestano mijenjanje mjesta injiciranja unutar određenog područja smanjuje rizik za razvoj takvih reakcija.
English: Turning the dose selector will not inject insulin.
Croatian: Okretanjem izbornika doze nećete injicirati inzulin.
English: Treatment with Actraphane helps to prevent complications from your diabetes.
Croatian: Liječenje lijekom Actraphane pomaže spriječiti komplikacije šećerne bolesti.
English: ► Keep the needle under your skin for at least 6 seconds to make sure that you have injected all the insulin.
Croatian: Zadržite iglu pod kožom najmanje 6 sekundi da budete sigurni da ste injicirali sav inzulin.
English: Turn the dose selector to select 2 units.
Croatian: Okrenite izbornik doze kako biste odabrali 2 jedinice.
English: Novo Nordisk Production SAS 45, Avenue d'Orléans F-28000 Chartres France
Croatian: Novo Nordisk Production SAS 45, Avenue d'Orléans F-28000 Chartres
English: In type 1 diabetes, untreated hyperglycaemic events eventually lead to diabetic ketoacidosis, which is potentially lethal.
Croatian: U šećernoj bolesti tipa 1 neliječena hiperglikemija u konačnici vodi u dijabetičku ketoacidozu, koja može biti smrtonosna.
English: Always carry glucose tablets or high sugar snacks with you, just in case.
Croatian: Za svaki slučaj uvijek nosite sa sobom tablete glukoze ili međuobrok bogat šećerom.
English: Combination of Actraphane with pioglitazone
Croatian: Kombinacija lijeka Actraphane s pioglitazonom
English: Patients must be instructed to always check the insulin label before each injection to avoid accidental mix-ups between Actraphane and other insulin products.
Croatian: Bolesnicima se mora objasniti da prije svakog injiciranja uvijek provjere naljepnicu na inzulinu kako bi izbjegli slučajne zamjene lijeka Actraphane i drugih inzulinskih pripravaka.
English: Injection sites should always be rotated within the same region in order to reduce the risk of lipodystrophy.
Croatian: Mjesta injiciranja unutar istog područja treba stalno mijenjati kako bi se umanjio rizik od lipodistrofije.
English: • Put the pen cap back on your InnoLet to protect the insulin from light.
Croatian: • Vratite zatvarač na brizgalicu InnoLet da biste zaštitili inzulin od svjetlosti.
English: When the needle is covered, carefully push the big outer needle cap completely on and then unscrew the needle.
Croatian: Kad je igla pokrivena, pažljivo gurnite veliki vanjski zatvarač igle do kraja, a potom odvijte iglu.