FrancophonIA/ELRC3.0 huggingface dataset:
English: The following table covers adverse drug reactions from the pooled studies mentioned above in patients with Parkinson's disease and from post-marketing experience.
Slovenian: V spodnji tabeli so navedeni neželeni učinki zdravila, zbrani v zgoraj omenjenih združenih študijah na bolnikih s Parkinsonovo boleznijo in iz izkušenj v obdobju trženja.
English: How to use the Leganto patches:
Slovenian: Kako uporabljati Leganto obliže:
English: A single daily dose should be initiated at 1 mg/24 h. Depending on the individual patient response, the dose may be increased in weekly increments of 1 mg/24 h to a maximum dose of 3 mg/24 h. The need for treatment continuation should be reconsidered every 6 months.
Slovenian: Enkratni dnevni odmerek začnemo z 1 mg/24 h. Odvisno od odziva posameznega bolnika lahko odmerek povečujemo v tedenskih korakih po 1 mg/24 h, do največjega odmerka 3 mg/24 h. Potrebo po nadaljnjem zdravljenju je treba pretehtati vsakih 6 mesecev.
English: hypersexuality, libido increased), confusional state, disorientation d,
Slovenian: (vključno s hiperseksualnostjo, povečanim libidom), zmedenost, dezorientiranost d,
English: This makes the S-shaped break in the liner open up.
Slovenian: Tako se razpoka v plasti v obliki črke S odpre.
English: If a generalised skin reaction (e.g. allergic rash, including erythematous, macular, papular rash or pruritus) associated with the use of Leganto is observed, Leganto should be discontinued.
Slovenian: Če se pojavijo splošne kožne reakcije (npr. alergijski izpuščaj, vključno z eritematoznim, makuloznim ali papuloznim izpuščajem, ali pruritus), povezane z uporabo obliža zdravila Leganto, je treba zdravljenje z zdravilom Leganto prekiniti.
English: • ‘anti-psychotic' medicines - used to treat certain mental illnesses
Slovenian: • ‘antipsihotična' zdravila - za zdravljenje določenih duševnih bolezni
English: • Restless Legs Syndrome (RLS) - this can be associated with discomfort in your legs or arms, urge to move around, sleep disturbance and feeling tired or sleepy during the day.
Slovenian: • sindroma nemirnih nog (RLS - Restless Legs Syndrome), ki je lahko povezan z nelagodjem v vaših nogah ali rokah, s potrebo po premikanju, motnjami spanja in občutkom utrujenosti ali zaspanosti čez dan. Ti simptomi se bodisi omilijo ali pa se njihovo trajanje skrajša ob zdravljenju z zdravilom Leganto.
English: The signs include: loss of muscle movement (akinesia), rigid muscles, fever, unstable blood pressure, increased heart rate (tachycardia), confusion, low level of consciousness (such as a coma).
Slovenian: Znaki vključujejo: izgubo mišične gibljivosti (akinezija), trde mišice, povišano telesno temperaturo, nestabilen krvni tlak, pospešeno bitje srca (tahikardija), zmedenost, zmanjšano stopnjo zavesti (kot je npr. koma).
English: Multipack: 84 (3 packs of 28) transdermal patches
Slovenian: Večkratno pakiranje: 84 (3 pakiranja po 28) transdermalnih obližev
English: If your liver problems get worse during treatment, talk to your doctor straight away.
Slovenian: Če se med zdravljenjem težave z jetri poslabšajo, se morate čimprej posvetovati s svojim zdravnikom.
English: Do not breast-feed during treatment with Leganto.This is because rotigotine may pass into your breast milk and affect your baby.
Slovenian: Ne dojite med zdravljenjem z zdravilom Leganto, saj lahko rotigotin prehaja v mleko in učinkuje na otroka.
English: Application site skin reactions may occur and are usually mild or moderate in intensity.
Slovenian: Na mestu aplikacije lahko nastanejo kožne reakcije, ki so ponavadi blage do zmerne.
English: • feeling of heartbeat (palpitation)
Slovenian: • občutek pospešenega bitja srca (palpitacija)
English: In a carcinogenicity study, male rats developed Leydig cell tumours and hyperplasia.
Slovenian: V študiji karcinogenosti so se pri podganjih samcih pojavili tumorji in hiperplazija Leydigovih celic.
English: • Stick the Leganto patch onto your skin as soon as you have opened the sachet and removed the release liner.
Slovenian: • Obliž zdravila Leganto nalepite na kožo takoj, ko odprete zaščitno vrečko in odstranite zaščitno plast.
English: Peripheral oedema has been observed in clinical trials conducted in patients with RLS.
Slovenian: Periferni edem so opazili v kliničnih preskušanjih pri bolnikih z RLS.
English: • disorientation
Slovenian: • dezorientiranost
English: This will remove any stickiness that stays on your skin.
Slovenian: Tako boste odstranili ostanke lepila, ki po odstranitvi obliža ostanejo na koži.
English: The sticky side of the patch is covered by a transparent release liner.
Slovenian: Lepljiva stran obliža je pokrita s prozorno zaščitno plastjo.
English: Leganto is for transdermal use.
Slovenian: Zdravilo Leganto je za transdermalno uporabo.
English: Rotigotine has not been investigated in this patient group.
Slovenian: Uporaba rotigotina v tej ciljni skupini ni bila raziskana.
English: In a randomized, open-label study (SP825) in patients with early-stage Parkinson's disease, 25 patients were randomized to rotigotine treatment and 26 to ropinirole.
Slovenian: V randomizirani, odprti študiji (SP825) z bolniki v zgodnji fazi Parkinsonove bolezni je 25 bolnikov prejemalo rotigotin in 26 ropinirol.
English: One half of the release liner should be removed and the sticky side should be applied and pressed firmly to the skin.
Slovenian: Eno polovico zaščitne plasti odstranimo, lepljivo stran pa namestimo in močno pritisnemo na kožo.
English: For both primary endpoints statistically significant differences have been observed for the doses 1 mg/24 h, 2 mg/24 h and 3 mg/24 h in comparison to placebo.
Slovenian: Končne vrednosti obeh parametrov so bile statistično pomembno različne pri odmerkih 1 mg/24 h, 2 mg/24 h and 3 mg/24 h v primerjavi s placebom.
English: The maximum dose is 8 mg/24 h.
Slovenian: Največji odmerek je 8 mg/24 h.
English: Psychotic disorder, obsessivecompulsive disorder, aggressive behaviour/ aggression b,
Slovenian: agitiranostd psihotične motnje, obsesivno kompulzivna motnja, nasilno vedenje/ agresivnost b,
English: Efficacy was determined by the subject's response to therapy in terms of responder and absolute points improvement in the scores of ADL and Motor Examination combined (UPDRS part II+III).
Slovenian: Učinkovitost je bila določena glede na bolnikov odziv na zdravljenje, izražen kot izboljšanje stopnje odziva bolnika in absolutnega števila točk skupnega rezultata ADL in motoričnega pregleda lestvice UPDRS (II.
English: The majority of application site reactions were mild or moderate in intensity, limited to the application areas and resulted in discontinuation of treatment with Leganto in only 4.3% of all subjects receiving Leganto.
Slovenian: Večina reakcij na mestu aplikacije je bila blagih ali zmernih, omejenih na mesto aplikacije, zdravljenje z zdravilom Leganto pa so zaradi njih prekinili le pri 4,3 % vseh bolnikov, ki so prejemali zdravilo Leganto.
English: Wash your hands with soap and water straight after handling the patch.
Slovenian: Takoj po namestitvi obliža si umijte roke z milom in vodo.
English: • fainting, feeling dizzy when standing up because of fall in blood pressure
Slovenian: • izguba zavesti, občutek omotice pri vstajanju zaradi padca krvnega tlaka
English: • involuntary muscle spasms (convulsion)
Slovenian: • nehoteni mišični krči (konvulzije)
English: In the double blind study SP650DB, 113 patients received rotigotine up to a maximum dose of 8 mg/24 h, 109 patients received rotigotine up to a maximum dose of 12 mg/24 h and 119 patients received placebo.
Slovenian: V dvojno slepi študiji SP650DB je 113 bolnikov prejemalo rotigotin do največjega odmerka 8 mg/24 h, 109 bolnikov je prejemalo rotigotin do največjega odmerka 12 mg/24 h, 119 bolnikov pa je prejemalo placebo.
English: Efficacy was determined by the subject's response to therapy in terms of responder and absolute improvement in the time spent “off”.
Slovenian: Učinkovitost je bila določena glede na bolnikov odziv na zdravljenje, izražen kot izboljšanje stopnje odziva bolnika in absolutnega časa v fazi »izklop«.
English: Leganto contains sodium metabisulphite (E223) Sodium metabisulphite (E223) may rarely cause severe hypersensitivity (allergic) reactions and bronchospasm (breathing distress caused by narrowing of the airways).
Slovenian: Zdravilo Leganto vsebuje natrijev metabisulfit (E223) Natrijev metabisulfit (E223) lahko redko povzroči resne preobčutljivostne (alergijske) reakcije in bronhospazem (težave z dihanjem zaradi zožanja dihalnih poti).
English: In two 6-month, double-blind, placebo-controlled studies, clinically relevant augmentation was observed in 1.5% of rotigotine-treated patients versus 0.5% of placebo treated patients.
Slovenian: Na osnovi dveh 6-mesečnih, dvojno slepih, s placebom nadzorovanih študijah, pa so opazili klinično pomembno avgmentacijo pri 1,5 % bolnikov, ki so se zdravili z rotigotinom, in pri 0,5 % bolnikov, ki so se zdravili s placebom.
English: Leganto is indicated for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome (RLS) in adults.
Slovenian: Zdravilo Leganto je indicirano za simptomatsko zdravljenje zmerne do hude idiopatične oblike sindroma nemirnih nog (RLS - Restless Legs Syndrome) pri odraslih.
English: Do not stop using Leganto without talking to your doctor.
Slovenian: Z uporabo zdravila Leganto ne smete prenehati brez posveta s svojim zdravnikom.
English: Peel off sachet in a plastic box: One side is composed of an ethylene copolymer (innermost layer), an aluminium foil, low density polyethylene film and paper; the other side is composed of polyethylene (innermost layer), aluminium, ethylene copolymer and paper.
Slovenian: Zaščitna vrečka (Peel-off) v plastični škatli: Ena stran je izdelana iz etilenskega kopolimera (notranja plast), aluminijske folije, filma iz polietilena nizke gostote in papirja; druga stran je izdelana iz polietilena (notranja plast), aluminija, etilenskega kopolimera in papirja.
English: Rotigotine plasma concentrations increase dose-proportionally over a dose range of 1 mg/24 h to 24 mg/24 h.
Slovenian: Koncentracija rotigotina v plazmi se povečuje sorazmerno z odmerkom pri intervalu odmerkov od 1 mg/24 h do 24 mg/24 h.
English: Leganto treatment initiation pack contains 4 different packages (one for each strength) with 7 patches each, for the first four weeks of therapy.
Slovenian: Komplet za začetno zdravljenje zdravila Leganto vsebuje 4 različna pakiranja (po eno za vsako jakost) za prve štiri tedne zdravljenja, v vsakem od njih je 7 obližev.
English: You can put a new patch on afterwards.
Slovenian: Po tem postopku lahko namestite nov obliž.
English: photopsia e
Slovenian: fotopsija e
English: Clinical studies in Parkinson's disease
Slovenian: Klinične študije pri Parkinsonovi bolezni
English: To open the sachet, hold the sachet in both hands.
Slovenian: Zaščitno vrečko odprite tako, da jo primete z obema rokama.
English: OUTER LABEL (WITH BLUE BOX) BOX OF 84 PATCHES CONTAINING 3 BOXES OF 28 PATCHES
Slovenian: PODATKI NA ZUNANJI OVOJNINI SAMO PAKIRANJA Z VEČ OBLIŽI ZUNANJA NALEPKA (Z “BLUE BOXOM”) ŠKATLA S 84 OBLIŽI, KI VSEBUJE 3 ŠKATLE S PO 28 OBLIŽI
English: Leganto should be discontinued gradually.
Slovenian: Zdravljenje z obližem zdravila Leganto je treba prekiniti postopno.
English: atrial fibrillation e, supraventricular tachycardia e
Slovenian: atrijska fibrilacija e, supraventrikularna tahikardija e
English: Unexpected accumulation of rotigotine levels may also occur at acute worsening of renal function (see section 5.2).
Slovenian: Akutno poslabšanje ledvične funkcije lahko nepričakovano povzroči kopičenje rotigotina (glejte poglavje 5.2).
English: • Flank (your side, between the ribs and hips).
Slovenian: • bok (med rebri in kolkom),
English: Application and instillation site reactions a
Slovenian: Splošne težave in spremembe na mestu aplikacije reakcije na mestu aplikacije a,
English: The patch should not be cut into pieces.
Slovenian: Obliža se ne sme rezati na dele.
English: 7 transdermal patches 28 transdermal patches 30 transdermal patches
Slovenian: 7 transdermalnih obližev 28 transdermalnih obližev 30 transdermalnih obližev
English: Leganto is used in adults to treat the signs and symptoms of:
Slovenian: Zdravilo Leganto se uporablja pri odraslih za zdravljenje znakov in simptomov:
English: Furthermore, in this study a higher dose of 4 mg/24 h that is unapproved in RLS was also used and led to higher rates of augmentation.
Slovenian: Višja stopnja avgmentacije se je pojavila pri večjem odmerku 4 mg/24 h, ki za zdravljenje RLS ni odobren, vendar je bil uporabljen v tej študiji.
English: Peel off sachet in a cardboard carton: One side is composed of an ethylene copolymer (innermost layer), an aluminium foil, low density polyethylene film and paper; the other side is composed of polyethylene (innermost layer), aluminium, ethylene copolymer and paper.
Slovenian: Zaščitna vrečka (Peel-off) v škatli: Ena stran je izdelana iz etilenskega kopolimera (notranja plast), aluminijske folije, filma iz polietilena nizke gostote in papirja; druga stran je izdelana iz polietilena (notranja plast), aluminija, etilenskega kopolimera in papirja.
English: • Hold the other half of the rigid release liner.
Slovenian: • Primite drugo polovico trdne zaščitne plasti.
English: These changes are well-known effects of dopamine agonists in rats after life-long therapy and assessed as not relevant to man.
Slovenian: Gre za dobro znane učinke agonistov dopamina na podgane pri dosmrtnem zdravljenju.
English: • feeling dizzy when standing up because of a fall in blood pressure
Slovenian: • občutek omotice pri vstajanju zaradi padca krvnega tlaka
English: This is known as ‘dopamine dysregulation syndrome' and can lead to use of too much Leganto
Slovenian: To imenujemo ‘dopaminski disregulacijski sindrom', ki lahko vodi do pretirane uporabe zdravila Leganto
English: Leganto can cause unusual urges or cravings which you cannot resist such as the impulse, drive or temptation to do things that could harm yourself or others - the symptoms are mainly seen in patients with Parkinson's disease.
Slovenian: Zdravilo Leganto lahko povzroči nenavadne težnje ali želje, ki se jim ne morete upreti in bi lahko škodovale vam ali drugim - ti simptomi so večinoma opazni pri bolnikih s Parkinsonovo boleznijo.
English: • generalised itching, skin irritation
Slovenian: • razširjeno srbenje, razdražena koža
English: • psychotic disorders
Slovenian: • psihotične motnje
English: How to take off a used patch
Slovenian: Kako odstraniti uporabljen obliž
English: Diarrhoea c
Slovenian: driska c
English: The differences were statistically significant (p<0.001 and p=0.003, respectively).
Slovenian: Razlike so bile statistično pomembne (p<0,001 v prvi skupini in p=0,003 v drugi).
English: This is known as ‘dopamine dysregulation syndrome' and can lead to use of too much Leganto.
Slovenian: To imenujemo ‘dopaminski disregulacijski sindrom', ki lahko vodi do pretirane uporabe zdravila Leganto.
English: It is square-shaped with rounded edges.
Slovenian: Je kvadraten z zaobljenimi robovi.
English: Which strength patches to use The dose of Leganto will depend on your illness - see below.
Slovenian: Katero jakost obližev uporabiti Odmerek zdravila Leganto bo odvisen od vaše bolezni - glejte spodaj.
English: Side effects when using Leganto for Parkinson's disease Tell your doctor, pharmacist or nurse if you get any of the following side effects:
Slovenian: Neželeni učinki pri uporabi zdravila Leganto za zdravljenje Parkinsonove bolezni Posvetujte se z zdravnikom, farmacevtom ali medicinsko sestro, če opazite katerega koli od naslednjih neželenih učinkov:
English: Irritability
Slovenian: razdražljivost
English: • Then put the sticky half of the patch onto your skin.
Slovenian: • Nato namestite lepljivo površino obliža na kožo.
English: The following table covers adverse drug reactions from the pooled studies mentioned above in patients with Restless Legs Syndrome and from post-marketing experience.
Slovenian: V spodnji tabeli so navedeni neželeni učinki zdravila, zbrani v zgoraj omenjenih združenih študijah na bolnikih s sindromom nemirnih nog in iz izkušenj v obdobju trženja.
English: Oedema peripheral, asthenic conditions a
Slovenian: periferni edem, astenična stanja a
English: Retinal degeneration was observed by transmission microscopy at a dose equivalent to 2.8 times the maximum recommended human dose on a mg/m² basis in a 3-month study in albino rats.
Slovenian: V 3-mesečni študiji na albino podganah so pri odmerkih, ki ustrezajo 2,8-kratnim največjim priporočenim odmerkom za človeka v mg/m2, s transmisijsko mikroskopijo opazili razpad mrežnice.
English: • Press the sticky side of the patch firmly into place.
Slovenian: • Lepljivo stran obliža močno pritisnite na kožo.
English: The strengths are 1 mg/24 h, 2 mg/24 h, 3 mg/24 h, 4 mg/24 h, 6 mg/24 h and 8 mg/24 h. The patches of 1 mg/24 h and 3 mg/24 h are used for the treatment of Restless Leg Syndrome, while the patches of 4 mg/24 h, 6 mg/24 h and 8 mg/24 h are used for the treatment of Parkinson's disease.
Slovenian: Jakosti so: 1 mg/24 h, 2 mg/24 h, 3 mg/24 h, 4 mg/24 h, 6 mg/24 h in 8 mg/24 h. Obliži jakosti 1 mg/24 h in 3 mg/24 h se uporabljajo za zdravljenje sindroma nemirnih nog, medtem ko se obliži jakosti 4 mg/24 h, 6 mg/24 h in 8 mg/24 h uporabljajo za zdravljenje Parkinsonove bolezni.
English: At the beginning of therapy dopaminergic adverse reactions such as nausea and vomiting may occur.
Slovenian: Na začetku zdravljenja se lahko pojavijo dopaminergični neželeni učinki, kot sta navzea in bruhanje.
English: These may include:
Slovenian: Te so lahko:
English: This makes sure the patch is touching the skin and the edges stick down well.
Slovenian: Tako zagotovite, da se obliž dotika kože in da so robovi dobro zalepljeni.
English: Leganto may cause other behaviours and abnormal thinking.
Slovenian: Zdravilo Leganto lahko povzroči tudi druge spremembe vedenja ali razmišljanja.
English: • increased heart rate
Slovenian: • povišan srčni utrip
English: Talk to your doctor before using Leganto if you are taking:
Slovenian: Pred uporabo zdravila Leganto se pogovorite s svojim zdravnikom, če jemljete:
English: Impulse control disorders
Slovenian: Motnje pri kontroli dražljajev
English: Perception disturbances a
Slovenian: motnje zaznavanja e
English: These occurred in 3.4% of Japanese subjects on rotigotine compared to 1.9% on placebo in double-blind Parkinson's disease and RLS studies.
Slovenian: Ti so se pojavili v dvojno slepi študiji Parkinsonove bolezni in RLS pri 3,4 % japonskih preiskovancev, ki so prejemali rotigotin, v primerjavi z 1,9 % preiskovancev, ki so prejemali placebo.
English: Hypersensitivity, which may include angioedema, tongue oedema and lip oedema
Slovenian: Bolezni imunskega sistema preobčutljivost, ki lahko vključuje angioedem, edem jezika in edem ustnic
English: • Stick the patch onto a different area of skin each day.
Slovenian: • Nalepite obliž vsak dan na drugo mesto na koži.
English: • nightmares
Slovenian: • nočne more
English: • binge eating (eating large amounts of food in a short period of time) or compulsive eating
Slovenian: • prenajedanje (uživanje velikih količin hrane v kratkem času) ali kompulzivno prehranjevanje
English: • constipation, dry mouth
Slovenian: • zaprtje, suha usta
English: Patients in each treatment group were maintained for 6 months.
Slovenian: Bolniki v vseh skupinah so svoj optimalni odmerek prejemali 6 mesecev.
English: The maximum dose is 8 mg per day.
Slovenian: Največji odmerek je 8 mg na dan.
English: • Do not cut the Leganto patches into pieces.
Slovenian: • Obliža zdravila Leganto ne razrežite na dele.
English: Clinical studies in Restless Legs Syndrome
Slovenian: Klinične študije pri sindromu nemirnih nog
English: Atrial fibrillation Supraventricular tachycardia
Slovenian: Srčne bolezni palpitacije atrijska fibrilacija supraventrikularna tahikardija
English: 116 patients were switched from previous oral therapy to receive up to 8 mg/24 h of rotigotine, among these were 47 who had been treated with ropinirole up to 9 mg/day, 47 who had been treated with pramipexole up to 2 mg/day and 22 who had been treated with cabergoline up to 3 mg/day.
Slovenian: 116 bolnikom so peroralno zdravljenje zamenjali z zdravljenjem do 8 mg/24 ur rotigotina; med njimi je bilo 47 bolnikov zdravljenih z do 9 mg ropinirola na dan, 47 bolnikov je prejemalo do 2 mg pramipeksola na dan in 22 bolnikov se je zdravilo z do 3 mg kabergolina na dan.
English: In both arms treatment was titrated to optimal or maximum dose of 8 mg/24 h or 9 mg/day, respectively.
Slovenian: V obeh skupinah so prilagodili odmerek na optimalnega 8 mg/dan ali maksimalnega 9 mg/dan.
English: • abnormal heart rhythm
Slovenian: • nenormalen ritem srca
English: Adverse drug reactions (ADRs) reported in more than 10% of patients treated with Leganto transdermal patch are nausea, vomiting, application site reactions, somnolence, dizziness and headache.
Slovenian: Neželeni učinki, o katerih so poročali pri več kot 10 % bolnikov, zdravljenih s transdermalnim obližem zdravila Leganto, so navzea, bruhanje, reakcije na mestu aplikacije, somnolenca, omotica in glavobol.
English: Based on the analysis of pooled placebo-controlled clinical trials comprising a total of 1,307 Legantoand 607 placebo-treated patients, 72.5% of the patients on Leganto and 58.0% of patients on placebo reported at least one adverse reaction.
Slovenian: Z analizo zbranih, s placebom nadzorovanih kliničnih preskušanj, v katerih je sodelovalo 1.307 bolnikov, zdravljenih z zdravilom Leganto, in 607 bolnikov, ki so prejemali placebo, so ugotovili, da se je pri 72,5 % bolnikov, ki so prejemali zdravilo Leganto, in pri 58,0 % bolnikov, ki so prejemali placebo, pojavil vsaj en neželen učinek.
English: • Release liner: Transparent fluoropolymer coated polyester film.
Slovenian: • Zaščitna plast: poliestrski film, prekrit s prozornim fluoropolimerom
English: In the double-blind study SP515, 201 patients received rotigotine, 200 received pramipexole and 100 patients received placebo.
Slovenian: V dvojno slepi študiji SP515 je 201 bolnikov prejemalo rotigotin, 200 jih je prejemalo pramipeksol, 100 bolnikov pa je prejemalo placebo.
English: • Hold the patch in both hands with the release liner facing you.
Slovenian: • Obliž primite v roke, tako da je zaščitna plast obrnjena proti vam.
English: Side effects more likely at the start of treatment You may feel sick (nausea) and vomit at the start of treatment.
Slovenian: Neželeni učinki, ki so bolj pogosti na začetku zdravljenja Na začetku zdravljenja se lahko pojavita občutek slabosti (navzea) in bruhanje.
English: • For doses higher than 8 mg/24 h (doses prescribed by your doctor above the available strengths), multiple patches must be applied to achieve the final dose.
Slovenian: • Za odmerke večje od 8 mg/24 h (odmerke, ki jih je predpisal zdravnik in so večji od razpoložljivih jakosti) morate uporabiti več obližev za doseg končnega odmerka.
English: In the double blind study SP512 Part I, 177 patients received rotigotine and 96 patients received placebo.
Slovenian: V dvojno slepi študiji SP512 del I je 177 bolnikov prejemalo rotigotin, 96 bolnikov pa placebo.
English: Transparent fluoropolymer coated polyester film.
Slovenian: Poliestrski film, prekrit s prozornim fluoropolimerom.
English: How to use the patch
Slovenian: Kako uporabljati obliž
English: For example, a daily dose of 14 mg may be reached by applying one patch of 6 mg/24 h and one patch of 8 mg/24 h and likewise, a daily dose of 16 mg can be reached by applying two patches of 8 mg/24 h.
Slovenian: Na primer, dnevni odmerek 14 mg se lahko doseže z uporabo enega obliža 6 mg/24 h in enega obliža 8 mg/24 h in podobno se lahko 16 mg doseže z uporabo dveh obližev 8 mg/24 h.
English: For doses higher than 8 mg/24 h (doses prescribed by your doctor above the available strengths), multiple patches must be applied to achieve the final dose.
Slovenian: Za odmerke večje od 8 mg/24 h (odmerke, ki jih je predpisal zdravnik in so večji od razpoložljivih jakosti) je treba uporabiti več obližev za doseg končnega odmerka.
English: • redness, increased sweating, itching
Slovenian: • rdečica, povečano znojenje, srbenje