FrancophonIA/ELRC3.0 huggingface dataset:
English: Dosage in patients with impaired kidney function If you have impaired kidney function, your doctor will decide upon a dose that suits your condition.
Slovenian: Odmerjanje pri bolnikih z ledvično okvaro V primeru, da imate ledvično okvaro, vam bo vaš zdravnik prilagodil odmerek v skladu z vašim stanjem.
English: Animal studies indicate a potential for reducing intrauterine growth at exposure levels, which are identical or slightly higher than at human exposure (see section 5.3).
Slovenian: V študijah na živalih so ugotovili, da memantin lahko zavira intrauterino rast pri izpostavljenosti, ki je enaka ali le malo večja od izpostavljenosti pri ljudeh (glejte poglavje 5.3).
English: Adverse reactions are ranked according to system organ class, using the following convention: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to
Slovenian: Neželeni učinki so razporejeni glede na organske sisteme ob uporabi naslednjega dogovora: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
English: HDPE bottles: use within 100 days after opening.
Slovenian: Plastenke HDPE: uporabite v 100 dneh po odprtju.
English: When patients were identified with concurrent worsening in all three domains, results showed a statistically significant effect of memantine in preventing worsening, as twice as many placebo-treated patients as memantine-treated patients showed worsening in all three domains (21 % vs. 11 %, p < 0.0001).
Slovenian: Pri bolnikih, kjer so ocenili hkratno poslabšanje vseh treh področij, so rezultati pokazali statistično značilen učinek memantina pri preprečevanju poslabšanja, saj se je pokazalo poslabšanje pri dvakrat več bolnikih, ki so prejemali placebo, kot pri bolnikih, zdravljenih z memantinom, na vseh treh področjih (21 % proti 11 %, p < 0,0001).
English: • Risk Management Plan (RMP) Not applicable.
Slovenian: ZDRAVILA • Načrt za obvladovanje tveganja (RMP)
English: A meta-analysis of patients with moderate to severe Alzheimer's disease (MMSE total scores < 20) from the six phase III, placebo-controlled, 6-month studies (including monotherapy studies and studies with patients on a stable dose of acetylcholinesterase inhibitors) showed that there was a statistically significant effect in favour of memantine treatment for the cognitive, global, and functional domains.
Slovenian: Metaanaliza bolnikov z zmerno do hudo Alzheimerjevo boleznijo (skupna ocena pri KPSS ob vključitvi < 20 točk), ki je zajela šest študij III. faze, kontroliranih s placebom in trajajočih šest mesecev (vključno s študijami zdravljenja v monoterapiji ter študijami bolnikov, ki so dobivali stabilni odmerek zaviralcev acetilholinesteraze), je pokazala statistično značilen učinek v korist zdravljenja z memantinom pri spoznavnih funkcijah ter globalnih in funkcionalnih področjih.
English: Concomitant administration of memantine with the antispasmodic agents, dantrolene or baclofen, can modify their effects and a dose adjustment may be necessary.
Slovenian: Sočasno dajanje memantina in spazmolitikov, dantrolena ali baklofena, lahko spremeni njune učinke, zato bo morda treba prilagoditi odmerke.
English: Renal handling also involves tubular reabsorption, probably mediated by cation transport proteins.
Slovenian: V ledvicah poteka tudi tubularna reabsorpcija, verjetno prek beljakovinskega kationskega transporta.
English: Concomitant use of N-methyl-D-aspartate (NMDA)-antagonists such as amantadine, ketamine or dextromethorphan should be avoided.
Slovenian: Sočasni uporabi drugih antagonistov N-metil-D-aspartata (NMDA), kot so amantadin, ketamin ali dekstrometorfan, se je treba izogniti.
English: On the basis of the clinical studies, the recommended dose for patients over the age of 65 years is 20 mg per day (20 mg once a day) as described above.
Slovenian: Na podlagi kliničnih študij je priporočen odmerek za bolnike starejše od 65 let, 20 mg na dan (20 mg enkrat na dan), kot je opisano zgoraj.
English: PVC/PVDC-Aluminium blisters.
Slovenian: PVC/PVDC-aluminijasti pretisni omoti.
English: 6.4 Special precautions for storage Do not store above 25°C.
Slovenian: 6.4 Posebna navodila za shranjevanje Shranjujte pri temperaturi do 25°C.
English: The patient experienced central nervous system symptoms such as restlessness, psychosis, visual hallucinations, proconvulsiveness, somnolence, stupor, and unconsciousness.
Slovenian: Pojavili so se simptomi, povezani s centralnim živčnim sistemom: nemir, psihoza, vidne halucinacije, nagnjenost h konvulzijam, zaspanost, stupor in nezavest.
English: For continuation of your treatment please consult your doctor.
Slovenian: Za nadaljevanje vašega zdravljenja se posvetujte z zdravnikom.
English: - If you take a large overdose of Nemdatine, contact your doctor or get medical advice, as you may need medical attention.
Slovenian: - V primeru, da ste zaužili prevelik odmerek zdravila Nemdatine, obvestite svojega zdravnika, ker boste morda potrebovali zdravniško obravnavo.
English: CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Slovenian: Predpisovanje in izdaja zdravila je le s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: Treatment initiation pack.
Slovenian: Pakiranje za začetno zdravljenje.
English: Although no causal relationship has been established, close monitoring of prothrombin time or INR is advisable for patients concomitantly treated with oral anticoagulants.
Slovenian: Čeprav vzročna povezanost ni bila dokazana, je pri bolnikih, ki se sočasno zdravijo s peroralnimi antikoagulanti, priporočljivo spremljanje protrombinskega časa oziroma INR.
English: Maintenance treatment can be continued for as long as a therapeutic benefit is favourable and the patient tolerates treatment with memantine.
Slovenian: Vzdrževalno zdravljenje lahko nadaljujemo, dokler obstaja korist za bolnika in dokler ga bolnik prenaša.
English: Logo]
Slovenian: logotip]
English: Hypertension Uncommon Venous thrombosis/thromboembolism
Slovenian: Občasni venska tromboza/tromboembolija
English: Ocular changes were inconsistently observed in repeat dose toxicity studies in rodents and dogs, but not in monkeys.
Slovenian: V študijah toksičnosti ponavljajočih se odmerkov so pri glodavcih in psih, ne pa tudi pri opicah, občasno opazili spremembe na očeh.
English: - In post-marketing experience, isolated cases with international normalized ratio (INR) increases have been reported in patients concomitantly treated with warfarin.
Slovenian: - V okviru izkušenj v obdobju trženja so pri bolnikih, ki so bili sočasno zdravljeni z varfarinom, poročali o osamljenih primerih povečanja mednarodnega umerjenega razmerja (INR).
English: You may experience increased symptoms as described in section 4 ‘Possible side effects'.
Slovenian: Morda boste občutili bolj izražene znake, ki so opisani v poglavju 4.
English: In single-dose pharmacokinetic (PK) studies in young healthy subjects, no relevant active substanceactive substance interaction of memantine with glyburide/metformin or donepezil was observed.
Slovenian: V raziskavah farmakokinetike (PK) posameznega odmerka pri mladih zdravih osebah ni bilo opaziti interakcij memantina z gliburidom/metforminom ali donepezilom.
English: In particular, Nemdatine may change the effects of the following medicines and their dose may need to be adjusted by your doctor: - amantadine, ketamine, dextromethorphan - dantrolene, baclofen - cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine - hydrochlorothiazide (or any combination with hydrochlorothiazide) - anticholinergics (substances generally used to treat movement disorders or intestinal cramps) - anticonvulsants (substances used to prevent and relieve seizures) - barbiturates (substances generally used to induce sleep) - dopaminergic agonists (substances such as L-dopa, bromocriptine) - neuroleptics (substances used in the treatment of mental disorders) - oral anticoagulants
Slovenian: Posebno v primeru, da skupaj z zdravilom Nemdatine jemljete naslednja zdravila, se učinki le teh lahko spremenijo in bo morda vaš zdravnik moral prilagoditi odmerek: - amantadin, ketamin, dekstrometorfan - dantrolen, baklofen - cimetidin, ranitidin, prokainamid, kinidin, kinin, nikotin - hidroklorotiazid (ali kombinacije zdravil, ki vsebujejo hidroklorotiazid) - antiholinergiki (zdravila, ki se na splošno uporabljajo za zdravljenje motenj gibanja in trebušnih krčev) - antikonvulzivi (zdravila za preprečevanje ali lajšanje epileptičnih krčev)
English: Memantine-treated patients showed a statistically significantly better effect than placebo-treated patients on the primary endpoints: Alzheimer´s disease assessment scale (ADAS-cog) (p = 0.003) and CIBIC-plus (p = 0.004) at week 24 (last observation carried forward (LOCF)).
Slovenian: Pri bolnikih, zdravljenih z memantinom, se je pokazal statistično značilno boljši učinek kot pri bolnikih, ki so prejemali placebo, pri primarnih ciljih študije: po lestvici za ocenjevanje Alzheimerjeve bolezni (Alzheimer´s disease assessment scale, ADAS-cog) (p = 0,003), po lestvici CIBIC-plus pa (p = 0,004) po 24 tednih (last observation carried forward, LOCF).
English: - The other ingredients are: Tablet core: Microcrystalline cellulose, crospovidone Type A, talc and magnesium stearate.
Slovenian: - Druge pomožne snovi so: Jedro tablete: mikrokristalna celuloza, krospovidon Tipa A, smukec in magnezijev stearat.
English: Day 1, 2, 3, 4, 5, 6, 7
Slovenian: Teden 1 Dan 1, 2, 3, 4, 5, 6, 7
English: You should inform your doctor if you have recently changed or intend to change your diet substantially (e.g. from normal diet to strict vegetarian diet) or if you are suffering from states of renal tubulary acidosis (RTA, an excess of acid-forming substances in the blood due to renal dysfunction (poor kidney function)) or severe infections of the urinary tract (structure that carries urine), as your doctor may need to adjust the dose of your medicine.
Slovenian: Obvestite zdravnika, če ste pred kratkim spremenili ali če nameravate bistveno spremeniti prehrano (npr. če preidete iz običajne hrane na strogo vegetarijansko prehrano), ali če imate ledvično tubularno acidozo (preveliko količino kislih spojin v krvi zaradi renalne disfunkcije (slabega delovanja ledvic)) ali če ste zboleli zaradi hudega vnetja sečil (strukture po kateri se prenaša seč).
English: The patient recovered without permanent sequelae.
Slovenian: Okreval je brez trajnih posledic.
English: Manufacturer Actavis hf.
Slovenian: Izdelovalca Actavis hf.
English: For continuation of the treatment please consult your doctor.
Slovenian: Za nadaljevanje zdravljenja se posvetujte z zdravnikom.
English: There is no indication that food influences the absorption of memantine.
Slovenian: Kot kaže, hrana ne vpliva na njegovo absorpcijo.
English: Talk to your doctor or pharmacist before taking Nemdatine - if you have a history of epileptic seizures - if you have recently experienced a myocardial infarction (heart attack), or if you are suffering from congestive heart failure or from an uncontrolled hypertension (high blood pressure).
Slovenian: Pred začetkom jemanja zdravila Nemdatine se posvetujte z zdravnikom ali farmacevtom - če ste v preteklosti imeli epileptične napade, - če ste pred kratkim preboleli srčni infarkt (srčna kap), imate kongestivno srčno odpoved ali neurejeno hipertenzijo (visok krvni tlak).
English: Daily doses of 20 mg lead to steady-state plasma concentrations of memantine ranging from 70 to 150 ng/ml (0.5 - 1 μmol) with large interindividual variations.
Slovenian: Ob dnevnih odmerkih po 20 mg so v stanju dinamičnega ravnovesja dosežene plazemske koncentracije memantina od 70 do 150 ng/ml (0,5-1 µmol), med posamezniki pa so velike razlike.
English: From the fourth week on, the usual dose is 20 mg memantine once a day.
Slovenian: Od četrtega tedna naprej je običajni odmerek 20 mg memantina enkrat dnevno.
English: Studies in volunteers have demonstrated linear pharmacokinetics in the dose range of 10 to 40 mg. Pharmacokinetic/pharmacodynamic relationship
Slovenian: Študije na zdravih prostovoljcih so pokazale, da ima memantin linearno farmakokinetiko pri odmerkih, velikih od 10 do 40 mg.
English: Main human metabolites are N-3,5-dimethyl-gludantan, the isomeric mixture of 4- and 6-hydroxymemantine, and 1-nitroso-3,5-dimethyl-adamantane.
Slovenian: Pri človeku so najpomembnejši presnovki N-3,5-dimetil-gludantan, izomerna mešanica 4- in 6-hidroksi-memantina in 1-nitrozo-3,5-dimetil-adamantan.
English: Phospholipidosis in pulmonary macrophages due to accumulation of memantine in lysosomes was observed in rodents.
Slovenian: Pri glodavcih so opazili fosfolipidozo v pljučnih makrofagih, ker se je memantin kopičil v lizosomih.
English: In the overdose cases below 140 mg or unknown dose the patients revealed symptoms from central nervous system (confusion, drowsiness, somnolence, vertigo, agitation, aggression, hallucination, and gait disturbance) and/or of gastrointestinal origin (vomiting and diarrhoea).
Slovenian: Pri prevelikih odmerkih do 140 mg in pri neznanih odmerkih so se pri bolnikih pokazali simptomi, povezani s centralnim živčnim sistemom (zmedenost, dremavost, zaspanost, vrtoglavica, vznemirjenost, agresivnosti, halucinacije in motnje hoje) in/ali prebavili (bruhanje in driska).
English: The usual starting dose is 5 mg memantine once a day for the first week.
Slovenian: Običajni začetni odmerek je 5 mg memantina enkrat dnevno v prvem tednu.
English: Ataxia and other preclinical signs have preceded the vacuolisation and necrosis.
Slovenian: Pred vakuolizacijo in nekrozo so se pojavili ataksija in drugi predklinični znaki.
English: In patients with mildly impaired renal function (creatinine clearance 50 − 80 ml/min) no dose adjustment is required.
Slovenian: Ledvična okvara Pri bolnikih z blago okvaro ledvičnega delovanja (kreatininski očistek 50 − 80 ml/min) prilagoditev odmerka ni potrebna.
English: Day 15, 16, 17, 18, 19, 20, 21
Slovenian: Teden 3 Dan 15, 16, 17, 18, 19, 20, 21
English: What is Nemdatine used for Nemdatine is used for the treatment of adult patients with moderate to severe Alzheimer's disease.
Slovenian: Zdravilo Nemdatine uporabljamo za zdravljenje odraslih bolnikov z zmerno do hudo Alzheimerjevo boleznijo.
English: Blister packs: 28, 30, 42, 50, 56, 60, 98 and 112 film-coated tablets.
Slovenian: Pretisni omoti: 28, 30, 42, 50, 56, 60, 98 in 112 filmsko obloženih tablet.
English: The study showed beneficial effects of memantine treatment in comparison to placebo at 6 months (observed cases analysis for the clinician´s interview based impression of change (CIBIC-plus): p = 0.025; Alzheimer´s disease cooperative study - activities of daily living (ADCS-ADLsev): p = 0.003; severe impairment battery (SIB): p = 0.002).
Slovenian: Po 6-mesečni monoterapiji z memantinom se je pri opazovanih bolnikih pokazalo izboljšanje v primerjavi s placebom (analiza opazovanih primerov po lestvici CIBIC-plus (vtis sprememb na podlagi kliničnega intervjuja, angl. clinician's interview based impression of change), p = 0,025; lestvici ADCS-ADLsev (vprašalnik vsakodnevnih aktivnosti, angl. Alzheimer's disease cooperative study - activities of daily living), p = 0,003; testi po SIB (sklop testov za hudo prizadetost, angl. severe impairment battery), p = 0,002).
English: The 20 mg tablets furthermore contain iron oxide red and yellow (E172).
Slovenian: 20 mg tablete vsebujejo tudi rdeči in rumeni železov oksid (E172).
English: Day 22, 23, 24, 25, 26, 27, 28
Slovenian: Teden 4 Dan 22, 23, 24, 25, 26, 27, 28
English: There are no or limited amount of data from the use of memantine in pregnant women.
Slovenian: Nosečnost Podatkov o uporabi memantina pri nosečnicah ni oziroma so omejeni.
English: Each tablet contains 5, 10, 15 or 20 mg of memantine hydrochloride equivalent to 4.15, 8.31, 12.46 or 16.62 mg memantine.
Slovenian: Ena filmsko obložena tableta vsebuje 5, 10, 15 ali 20 mg memantinijevega klorida, kar ustreza 4,15, 8,31, 12,46 ali 16,62 mg memantina.
English: Uncommon Confusion Uncommon Hallucinations1
Slovenian: Občasni halucinacije1
English: Day 8, 9, 10, 11, 12, 13, 14
Slovenian: Teden 2 Dan 8, 9, 10, 11, 12, 13, 14
English: A pivotal monotherapy study of memantine in the treatment of mild to moderate Alzheimer's disease (MMSE total scores at baseline of 10 to 22) included 403 patients.
Slovenian: Temeljna študija memantina v monoterapiji pri zdravljenju bolnikov z blago do zmerno Alzheimerjevo boleznijo (skupna ocena pri KPSS ob vključitvi od 10 do 22 točk) je zajela 403 bolnike.
English: In patients with severe renal impairment (creatinine clearance 5 - 29 ml/min) daily dose should be 10 mg per day.
Slovenian: Pri bolnikih s hudo okvaro ledvičnega delovanja (kreatininski očistek 5 − 29 ml/min) naj bo dnevni odmerek 10 mg.
English: Breast-feeding Women taking Nemdatine should not breast-feed.
Slovenian: Dojenje Ženske, ki jemljejo zdravilo Nemdatine, ne smejo dojiti.
English: This is increased to 10 mg memantine in the second week and to 15 mg memantine once a day in the third week.
Slovenian: V drugem tednu povišamo odmerek na 10 mg memantina enkrat dnevno in na 15 mg memantina enkrat dnevno v tretjem tednu.
English: In rats, foetal growth reduction was noted at exposure levels, which are identical or slightly higher than at human exposure.
Slovenian: Pri podganah so pri odmerkih, ki so bili primerljivi ali malo večji kot pri ljudeh, ugotovili zmanjšano rast ploda.
English: MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE
Slovenian: A. IZDELOVALEC, ODGOVOREN ZA SPROŠČANJE SERIJ
English: - The other ingredients for Nemdatine 5, 10, 15 and 20 mg film-coated tablets are: Tablet core: Microcrystalline cellulose, crospovidone Type A, talc and magnesium stearate.
Slovenian: - Druge pomožne snovi za Nemdatine 5, 10, 15 in 20 mg filmsko obložene tablete so: Jedro tablete: mikrokristalna celuloza, krospovidon Tipa A, smukec in magnezijev stearat.
English: Also, Nemdatine may change your reactivity, making driving or operating machinery inappropriate.
Slovenian: Prav tako Nemdatine lahko vpliva na vašo sposobnost odzivanja, zato se vožnja in upravljanje strojev ne priporoča.
English: HDPE bottle: 100 film-coated tablets.
Slovenian: Plastenka HDPE: 100 filmsko obloženih tablet.
English: 28 film-coated tablets 30 film-coated tablets 42 film-coated tablets 50 film-coated tablets 56 film-coated tablets 60 film-coated tablets 98 film-coated tablets 112 film-coated tablets
Slovenian: 28 filmsko obloženih tablet 30 filmsko obloženih tablet 42 filmsko obloženih tablet 50 filmsko obloženih tablet 56 filmsko obloženih tablet 60 filmsko obloženih tablet 98 filmsko obloženih tablet 112 filmsko obloženih tablet
English: Paediatric population No data are available.
Slovenian: Podatkov ni na voljo.
English: From the fourth week on, the usual dose is 4 tablets once a day (1x 20 mg).
Slovenian: Od četrtega tedna naprej je običajni odmerek 4 tablete enkrat dnevno (1x20 mg).
English: Do not take Nemdatine - if you are allergic to memantine hydrochloride or any of the other ingredients of this medicine
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Nemdatine Ne jemljite zdravila Nemdatine - če ste alergični na memantinijev klorid ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Do not use this medicine after the expiry date which is stated on the carton, blister and bottle label after ‘EXP'.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli, pretisnem omotu in na ovoju plastenke poleg oznake EXP. Datum izteka roka uporabnosti se nanaša na zadnji dan navedenega meseca.
English: On the basis of the clinical studies, the recommended dose for patients over the age of 65 years is 20 mg per day (four 5 mg film-coated tablets (20 mg), two 10 mg film-coated tablets (20 mg) or one 20 mg film-coated tablet (20 mg) once a day) as described above.
Slovenian: Na podlagi kliničnih študij je priporočen odmerek za bolnike starejše od 65 let, 20 mg na dan (štiri 5-miligramske filmsko obložene tablete (20 mg), dve 10-miligramski filmsko obloženi tableti (20 mg) ali ena 20-miligramska filmsko obložena tableta (20 mg) enkrat na dan), kot je opisano zgoraj.
English: SN:
Slovenian: PC: SN:
English: Alkalisation of urine may result from drastic changes in diet, e.g. from a carnivore to a vegetarian diet, or from the massive ingestion of alkalising gastric buffers.
Slovenian: Alkalizacija urina lahko nastopi po izraziti spremembi v prehrani, npr. po prehodu z običajne prehrane na vegetarijansko, ali pri čezmernem zaužitju alkalnih učinkovin za uravnavanje želodčne kisline.
English: These factors include drastic changes in diet, e.g. from a carnivore to a vegetarian diet, or a massive ingestion of alkalising gastric buffers.
Slovenian: Med te dejavnike spadajo izrazite spremembe v prehranjevanju, npr. prehod z običajne prehrane na vegetarijansko ali čezmerno zaužitje alkalno delujočih snovi proti želodčni kislini.
English: The maximum daily dose is 20 mg per day.
Slovenian: Največji dnevni odmerek je 20 mg na dan.
English: In patients with moderate renal impairment (creatinine clearance 3049 ml/min) daily dose should be 10 mg per day.
Slovenian: Pri bolnikih z zmerno okvaro ledvičnega delovanja (kreatininski očistek 30 − 49 ml/min) naj bo dnevni odmerek 10 mg.
English: How to take Nemdatine
Slovenian: Kako jemati zdravilo Nemdatine
English: Standard clinical procedures to remove active substance material, e.g. gastric lavage, carbo medicinalis (interruption of potential entero-hepatic recirculation), acidification of urine, forced diuresis should be used as appropriate.
Slovenian: Pri odstranjevanju učinkovine uporabljamo ustrezne standardne klinične postopke, kot so izpiranje želodca, medicinsko oglje (preprečevanje morebitne enterohepatične recirkulacije), nakisanje urina, prisilna diureza.
English: In man, about 80 % of the circulating memantine-related material is present as the parent compound.
Slovenian: Pri človeku je okoli 80 % memantina v obtoku v izvorni (nespremenjeni) obliki.
English: What you need to know before you take Nemdatine
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Nemdatine Ne jemljite zdravila Nemdatine
English: Contents of the pack and other information
Slovenian: Shranjevanje zdravila Nemdatine Vsebina pakiranja in dodatne informacije
English: Each pack with 28 film-coated tablets for a 4 week treatment schedule contains: Week 1: 7 film-coated tablets of Nemdatine 5 mg
Slovenian: Vsako pakiranje z 28 filmsko obloženimi tabletami za štiri tedenski program zdravljenja vsebuje: 7 filmsko obloženih tablet Nemdatine 5 mg
English: The patient should take four 5 mg film-coated tablets (20 mg), two 10 mg film-coated tablets (20 mg) or one 20 mg film-coated tablet (20 mg) per day.
Slovenian: Bolnik mora jemati štiri 5-miligramske filmsko obložene tablete (20 mg), dve 10-miligramski filmsko obloženi tableti (20 mg) ali eno 20-miligramsko filmsko obloženo tableto (20 mg) na dan.
English: For up-titration other tablet strengths are available.
Slovenian: Za lažje povečevanje odmerka so na voljo tudi druge jakosti tablete.
English: Do not use this medicine after the expiry date which is stated on the carton and blister after ‘EXP'.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na pretisnem omotu poleg oznake EXP. Datum izteka roka uporabnosti se nanaša na zadnji dan navedenega meseca.
English: At a dose of memantine of 20 mg per day the CSF levels match the ki-value (ki = inhibition constant)
Slovenian: Pri odmerku 20 mg memantina na dan so vrednosti v CSL skladne z vrednostjo ki (ki = konstanta inhibicije) memantina, ki je v frontalnem korteksu pri človeku 0,5°µmol.
English: INFORMATION IN BRAILLE Nemdatine 20 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Nemdatine 20 mg
English: Bottle: 100 film-coated tablets.
Slovenian: Plastenka: 100 filmsko obloženih tablet.