FrancophonIA/ELRC3.0 huggingface dataset:
English: • Third trimester of pregnancy (see section 4.6).
Croatian: • U trećem tromjesečju trudnoće (vidjeti dio 4.6).
English: Do not take a double dose to make up for a forgotten tablet.
Croatian: Ne uzimajte dvostruku dozu kako biste nadoknadili propuštenu tabletu.
English: If you have had a heart attack, it should be prescribed for at least four weeks.
Croatian: Ako ste imali srčani udar, liječenje bi trebalo trajati najmanje 4 tjedna.
English: 74770 Opava-Komarov Czech Republic
Croatian: 74770 Opava-Komarov Češka Republika
English: In addition, due to the presence of ASA, its use is also contraindicated in:
Croatian: Također, zbog prisustva ASK, njegova je primjena također kontraindicirana:
English: Their frequency is defined using the following conventions: common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Croatian: Njihova je učestalost definirana na sljedeći način: česte (≥1/100 do <1/10); manje česte (≥1/1000 do <1/100); rijetke (≥1/10 000 do <1/1000); vrlo rijetke (<1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: After first opening bottle: 30 days
Croatian: Nakon prvog otvaranja boce: 30 dana
English: Ask your doctor or pharmacist for advice before taking any medicine.
Croatian: Upitajte svog liječnika ili ljekarnika za savjet prije nego što uzmete bilo koji lijek.
English: You should specifically tell your doctor if you take
Croatian: Posebno je važno obavijestiti liječnika ako uzimate
English: Therefore, such addition should be undertaken with caution outside of clinical situations where the combination has proven to be beneficial.
Croatian: Stoga je tu kombinaciju potrebno primjenjivati s oprezom izvan kliničkih situacija u kojima se pokazala korisnom.
English: At low concentrations (<100 micrograms/ml), approximately 90% of salicylic acid is bound to albumin.
Croatian: Pri niskim koncentracijama (<100 μg/ml), otprilike 90% salicilatne kiseline vezano je za albumin.
English: In addition, your doctor may identify changes in your blood or urine tests.
Croatian: Također, liječnik može identificirati promjene u rezultatima pretraga krvi ili urina.
English: An occasional use of ASA (no more than 1,000 mg in any 24-hour period) should generally not cause a problem, but prolonged use of ASA in other circumstances should be discussed with your doctor or pharmacist.
Croatian: Povremeno uzimanje ASK (ne više od 1000 mg unutar 24 sata) ne bi smjelo predstavljati nikakav problem, ali o duljem uzimanju ASK pod drugim okolnostima trebate razgovarati sa svojim liječnikom ili ljekarnikom.
English: Following toxic doses (10-20 g), the plasma half-life may be increased to over 20 hours.
Croatian: Nakon toksičnih doza (10-20 g) poluvijek u plazmi može biti produljen na preko 20 sati.
English: In COMMIT, the overall rate of noncerebral major bleeding or cerebral bleeding was low and similar in both groups.
Croatian: U studiji COMMIT ukupna stopa necerebralnog velikog krvarenja ili cerebralnog krvarenja bila je niska i slična u obje skupine.
English: The patient population included 19.7% women and 29.2% patients ≥65 years.
Croatian: U populaciji ispitanika bilo je 19,7% žena i 29,2% bolesnika ≥65 godina.
English: Do not use this medicine if you notice any visible signs of deterioration
Croatian: Ovaj se lijek ne smije upotrijebiti ako primijetite vidljive znakove odstupanja u kakvoći.
English: From the beginning of the sixth month of pregnancy, all prostaglandin synthesis inhibitors may expose:
Croatian: Od početka šestog mjeseca trudnoće, svi inhibitori sinteze prostaglandina mogu
English: Reye's Syndrome is a very rare disease which can be fatal.
Croatian: Reyeov sindrom je vrlo rijetka bolest koja može biti smrtonosna.
English: You should not breast-feed while using this medicine.
Croatian: Ne smijete dojiti dok uzimate ovaj lijek.
English: Caution required due to ASA
Croatian: Oprez potreban zbog ASK
English: • the mother and the neonate, at the end of pregnancy, to: - possible prolongation of bleeding time, an anti-aggregating effect which may occur even
Croatian: • majku i novorođenče, na kraju trudnoće, izložiti: - mogućem produljenju vremena krvarenja, anti-agregacijskom učinku koji se može javiti i
English: - cardiopulmonary toxicity (with premature closure of the ductus arteriosus and pulmonary
Croatian: - kardiopulmonalnoj toksičnosti (s preranim zatvaranjem ductus arteriosus i plućnom
English: Do not use this medicine after the expiry date which is stated on the carton, bottle and blister after EXP.
Croatian: Ovaj lijek ne smije se upotrijebiti nakon isteka roka valjanosti navedenog na kutiji, boci i blisteru iza EXP.
English: • Active pathological bleeding such as peptic ulcer or intracranial haemorrhage.
Croatian: • Aktivnog patološkog krvarenja kao što je peptički ulkus ili intrakranijalno krvarenje.
English: Uricosurics (benzbromarone, probenecid, sulfinpyrazone)
Croatian: Urikozurici: (benzbromaron, probenecid, sulfinpirazon)
English: Patients should be followed carefully for any signs of bleeding including occult bleeding, especially during the first weeks of treatment and/or after invasive cardiac procedures or surgery.
Croatian: Bolesnike je potrebno pomno nadzirati radi bilo kakvih znakova krvarenja, uključujući okultno krvarenje, poglavito tijekom prvih tjedana liječenja i/ili nakon invazivnih kardioloških postupaka ili kirurških zahvata.
English: Platelets are very small structures in the blood which clump together during blood clotting.
Croatian: Trombociti su vrlo mala krvna tjelešca koja se međusobno sljepljuju tijekom zgrušavanja krvi.
English: For the treatment of this condition your doctor may have placed a stent in the blocked or narrowed artery to restore effective blood flow.
Croatian: Za liječenje tog stanja liječnik Vam je možda ugradio stent u začepljenu ili suženu arteriju da bi ponovno uspostavio normalan protok krvi.
English: There is insufficient clinical experience regarding the use of doses above 100 mg/day up to 500 mg/day.
Croatian: Ne postoji dostatno kliničko iskustvo u primjeni doza iznad 100 mg/dan do 500 mg/dan.
English: The results obtained in populations with different characteristics (e.g. unstable angina or non-Q-wave MI, low to high risk levels, diabetes, need for revascularisation, age, gender, etc.) were consistent with the results of the primary analysis.
Croatian: Rezultati koji su dobiveni u različitim populacijama (primjerice, nestabilna angina ili non-Q infarkt miokarda, niska do visoka razina rizika, šećerna bolest, potreba revaskularizacije, dob, spol itd.) bili su u skladu s rezultatima primarne analize.
English: • low blood sugar
Croatian: • niska razina šećera u krvi,
English: • If you are allergic to clopidogrel, acetylsalicylic acid (ASA) or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na klopidogrel, acetilsalicilatnu kiselinu (ASK) ili na bilo koji drugi sastojak ovoga lijeka (naveden u dijelu 6)
English: This is linked to the way your medicine works as it prevents the ability of blood clots to form.
Croatian: To je povezano s načinom na koji Vaš lijek djeluje jer sprječava mogućnost stvaranja krvnih ugrušaka.
English: - In patients with ST segment elevation acute myocardial infarction: Therapy should be started as early as possible after symptoms start and continued for at least four weeks.
Croatian: - Kod bolesnika s akutnim infarktom miokarda s elevacijom ST segmenta: liječenje je potrebno započeti čim je ranije moguće nakon pojave simptoma i nastaviti kroz najmanje četiri tjedna.
English: By preventing this clumping in some types of blood vessels (called arteries), antiplatelet medicinal products reduce the chances of blood clots forming (a process called atherothrombosis).
Croatian: Sprječavanjem tog sljepljivanja u nekim vrstama krvnih žila (arterijama), antitrombocitni lijekovi smanjuju mogućnost stvaranja krvnih ugrušaka (proces koji se naziva aterotromboza).
English: • changes in taste of foods
Croatian: • poremećaj okusa hrane
English: Interactions with the following medicinal products have been reported with ASA:
Croatian: Zabilježene su interakcije između sljedećih lijekova i ASK:
English: The elimination half-life of the main circulating (inactive) metabolite was 8 hours after single and repeated administration.
Croatian: Poluvrijeme izlučivanja glavnog cirkulirajućeg (neaktivnog) metabolita iznosi 8 sati, nakon jednokratne i ponovljene primjene.
English: • skin allergy
Croatian: • kožna alergija
English: • generalised allergic reactions (for example, overall sensation of heat with sudden general discomfort until fainting)
Croatian: • generalizirane alergijske reakcije (primjerice opći osjećaj vrućine s iznenadnom općom nelagodom do nesvjestice)
English: Other medicinal products: A number of other clinical studies have been conducted with clopidogrel and other concomitant medicinal products to investigate the potential for pharmacodynamic and pharmacokinetic (PK) interactions.
Croatian: Ostali lijekovi: Provedeno je nekoliko drugih kliničkih studija s klopidogrelom i drugim istodobno primjenjivanim lijekovima kako bi se ispitala mogućnost farmakodinamičkih i farmakokinetičkih interakcija.
English: - For more than 12 hours: patients should take the next dose at the regular scheduled time and should not double the dose.
Croatian: - i prošlo je više od 12 sati: bolesnici trebaju uzeti sljedeću dozu prema uobičajenom rasporedu i ne smiju uzeti dvostruku dozu.
English: The safety and efficacy of clopidogrel/acetylsalicylic acid in children and adolescents under 18 years old have not been established.
Croatian: Sigurnost i djelotvornost klopidogrela/acetilsalicilatne kiseline u djece i adolescenata mlađih od 18 godina još nije utvrđena.
English: Caution is required because ASA may inhibit the effect of uricosuric agents through competitive elimination of uric acid.
Croatian: Potreban je oprez jer ASK može inhibirati učinak urikozurika putem kompetitivne eliminacije mokraćne kiseline.
English: The combination of clopidogrel/acetylsalicylic acid should not be used during the first two trimesters of pregnancy unless the clinical condition of the woman requires treatment with clopidogrel/ASA.
Croatian: Kombinacija klopidogrel/acetilsalicilatna kiselina ne smije se primjenjivati tijekom prva dva tromjesečja trudnoće osim ako kliničko stanje žene ne iziskuje liječenje klopidogrelom/ASK.
English: Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Croatian: Bolesnici s rijetkim nasljednim poremećajima nepodnošenja galaktoze, nedostatkom Lapp laktaze ili glukoza-galaktoza malapsorpcijom ne bi trebali uzimati ovaj lijek.
English: Where elective surgery is being considered, the need for dual antiplatelet therapy should be reviewed and consideration given to the use of a single antiplatelet agent.
Croatian: Ako se razmatra elektivni kirurški zahvat, potrebno je ponovno razmotriti potrebu za dvostrukom antitrombocitnom terapijom i uzeti u obzir mogućnost uporabe samo jednog antitrombotika.
English: • excessive gas in stomach or intestines
Croatian: • povećano stvaranje plinova u želucu ili crijevima
English: Inhibition of prostaglandin synthesis may adversely affect the pregnancy and/or the embryo/foetal development.
Croatian: Inhibicija sinteze prostaglandina može štetno utjecati na trudnoću i embrionalni/fetalni razvoj.
English: Side effects with unknown frequency (frequency cannot be estimated from the available data):
Croatian: Nuspojave nepoznate učestalosti (učestalost se ne može procijeniti na osnovi dostupnih podataka):
English: Recent transient ischaemic attack or stroke
Croatian: Nedavna tranzitorna ishemijska ataka ili moždani udar
English: If you have been told by your doctor to stop treatment temporarily, ask your doctor when to restart the treatment.
Croatian: Ako Vam je liječnik rekao da privremeno prekinete uzimanje lijeka, upitajte ga kada trebate nastaviti terapiju.
English: Clopidogrel: During non-clinical studies in rat and baboon, the most frequently observed effects were liver changes.
Croatian: Klopidogrel: tijekom nekliničkih ispitivanja na štakorima i babunima, najčešće su uočene promjene na jetri.
English: Thrombotic Thrombocytopenic Purpura (TTP) has been reported very rarely following the use of clopidogrel, sometimes after a short exposure.
Croatian: Trombotička trombocitopenična purpura (TTP) zabilježena je vrlo rijetko nakon primjene klopidogrela, katkad nakon kratke izloženosti lijeku.
English: Patients should inform physicians and dentists that they are taking the combination of clopidogrel/acetylsalicylic acid before any surgery is scheduled and before any new medicinal product is taken.
Croatian: Bolesnici moraju obavijestiti liječnika i stomatologa o uzimanju kombinacije klopidogrela i acetilsalicilatne kiseline prije nego što se planira bilo kakav kirurški zahvat i prije nego što počnu uzimati bilo koji novi lijek.
English: If you forget to take Clopidogrel/Acetylsalicylic acid Teva If you forget to take a dose of Clopidogrel/Acetylsalicylic acid Teva, but remember within 12 hours of your usual time, take your tablet straight away and then take your next tablet at the usual time.
Croatian: Ako ste zaboravili uzeti Klopidogrel/acetilsalicilatna kiselinaTeva Ako zaboravite uzeti dozu lijeka Klopidogrel/acetilsalicilatna kiselinaTeva, ali se toga sjetite u roku od 12 sati, odmah uzmite tabletu, a sljedeću tabletu uzmite u uobičajeno vrijeme.
English: Acetylsalicylic Acid: Single-dose studies have shown that the oral toxicity of ASA is low.
Croatian: Acetilsalicilatna kiselina: ispitivanja sa jednokratnom dozom pokazala su da je oralna toksičnost ASK niska.
English: Until the 24th amenorrhea week (5th month of pregnancy), acetylsalicylic acid should not be given unless clearly necessary.
Croatian: Do 24. tjedna amenoreje (5. mjesec trudnoće), acetilsalicilatna kiselina ne smije se upotrebljavati osim ako to nije nužno potrebno.
English: In animals, administration of a prostaglandin synthesis inhibitor has been shown to result in reproductive toxicity (see section 5.3).
Croatian: Kod životinja je primjena inhibitora sinteze prostaglandina dovela do reproduktivne toksičnosti (vidjeti dio 5.3).
English: Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole.
Croatian: Manje izraženo smanjenje izloženosti metabolitu opaženo je kod pantoprazola i lanzoprazola.
English: After single and repeated oral doses of 75 mg per day, clopidogrel is rapidly absorbed.
Croatian: Nakon jednokratne i ponovljene peroralne doze od 75 mg dnevno, klopidogrel se brzo apsorbira.
English: Aluminium + Dessicant - Aluminium blisters.
Croatian: Aluminij + sredstvo za sušenje - aluminijski blisteri.
English: Cross-reactions among thienopyridines
Croatian: Križne reakcije između tienopiridina
English: • gout (a condition of painful, swollen joints caused by uric acid crystals)
Croatian: • giht (stanje bolnih, nateknutih zglobova uzrokovanih kristalima mokraćne kiseline)
English: At high ASA doses, the elimination of salicylic acid follows zero-order kinetics (i.e., the rate of elimination is constant in relation to plasma concentration), with an apparent half-life of 6 hours or higher.
Croatian: Pri visokim dozama ASK, eliminacija salicilatne kiseline slijedi kinetiku nultog reda (tj. brzina eliminacije je konstantna u odnosu na koncentraciju u plazmi), s prividnim poluvijekom od 6 sati i više.
English: TEVA UK Limited BRAMPTON ROAD HAMPDEN PARK EASTBOURNE, EAST SUSSEX,BN22 9AG, United Kingdom
Croatian: TEVA UK Limited BRAMPTON ROAD HAMPDEN PARK EASTBOURNE, EAST SUSSEX,BN22 9AG, Ujedinjeno Kraljevstvo
English: - inhibition of uterine contractions resulting in delayed or prolonged labour.
Croatian: - inhibiciji uterinih kontrakcija što dovodi do odgođenog ili produljenog poroda.
English: The European Medicines Agency has waived the obligation to submit the results of studies with the combination of clopidogrel/acetylsalicylic acid in all subsets of the paediatric population in the treatment of coronary atherosclerosis (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove je izuzela obvezu podnošenja rezultata ispitivanja kombinacije klopidogrel/acetilsalicilatna kiselina u svim podskupinama pedijatrijske populacije u liječenju koronarne ateroskleroze (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Clinical trial data support use up to 12 months, and the maximum benefit was seen at 3 months (see section 5.1).
Croatian: Rezultati kliničkih ispitivanja podupiru trajanje liječenja do najviše 12 mjeseci, a najveća korist zabilježena je nakon trećeg mjeseca liječenja (vidjeti dio 5.1).
English: 305, Opava - Komárov,
Croatian: Ostravská 29, č.p. 305, Opava - Komárov,
English: A patient with poor metaboliser status will possess two loss-of-function alleles as defined above.
Croatian: Bolesnici sa statusom sporih metabolizatora imaju 2 nefunkcionalna alela kako je definirano gore.
English: • hallucinations
Croatian: • halucinacije
English: Therefore, the recommendations below for doses of 500 mg/day and above apply also for this dose range.
Croatian: Stoga se preporuke za doze od 500 mg/dan i više primjenjuju i na ovaj raspon doza.
English: If acetylsalicylic acid is used by a woman attempting to conceive, or until the 24th amenorrhea week (5th month of pregnancy), the dose should be kept as low and duration of treatment as short as possible.
Croatian: Ako acetilsalicilatnu kiselinu uzima žena koja pokušava zanijeti, ili do 24. tjedna amenoreje (5. mjesec trudnoće), doza treba biti što je moguća niža a trajanje liječenja što kraće.
English: This was associated with a reduction of the mean inhibition of platelet aggregation by 15% and 11%, respectively.
Croatian: To je bilo povezano sa smanjenjem srednje vrijednosti inhibicije agregacije trombocita od 15%, odnosno 11%.
English: • if you have a history of asthma or allergic reactions including allergy to any medicine used to
Croatian: • ako u povijesti bolesti imate astmu ili alergijske reakcije uključujući alergiju na bilo koji lijek koji se koristi za liječenje vaše bolesti.
English: Other alleles associated with absent or reduced metabolism are less frequent and include CYP2C19*4, *5, *6, *7, and *8.
Croatian: Ostali aleli povezani sa nedostatkom metabolizma ili smanjenim metabolizmom su manje zastupljeni i uključuju CYP2C19*4, *5, *6, *7 i *8.
English: Therefore, concomitant use should be undertaken with caution (see section
Croatian: Zbog toga je pri istodobnoj primjeni potreban oprez (vidjeti dio
English: It is preferable not to take this product during first and second trimesters of pregnancy.
Croatian: Ne preporučuje se uzimanje lijeka u prvom i drugom tromjesečju trudnoće.
English: Other interactions with ASA
Croatian: Druge interakcije s ASK
English: Other side effects include:
Croatian: • Drugi sastojci su:
English: If patients must temporarily stop antiplatelet therapy, the combination of clopidogrel/acetylsalicylic acid should be discontinued 7 days prior to surgery.
Croatian: Ako bolesnik mora privremeno prestati uzimati antitrombotsku terapiju, davanje kombinacije klopidogrela i acetilsalicilatne kiseline potrebno je prekinuti 7 dana prije kirurškog zahvata.
English: The following symptoms can also arise: hyperthermia and perspiration, leading to dehydration, restlessness, convulsions, hallucinations and hypoglycaemia.
Croatian: Također, mogu se pojaviti i sljedeći simptomi: hipertermija i znojenje koji vode do dehidracije, uznemirenost, konvulzije, halucinacije i hipoglikemija.
English: The plasma concentrations of the active metabolite was 20% reduced (loading dose) and 14% reduced (maintenance dose) during concomitant treatment with pantoprazole 80 mg once daily.
Croatian: Koncentracija aktivnog metabolita u plazmi bila je smanjena za 20% (udarna doza) i 14% (doza održavanja) tijekom istodobne terapije pantoprazolom u dozi od 80 mg jednom na dan.
English: For patients who did not undergo angiography, the primary endpoint was death or recurrent myocardial infarction by Day 8 or by hospital discharge.
Croatian: Za bolesnike kojima nije učinjena angiografija primarni ishod bila je smrt ili ponovni infarkt miokarda do osmog dana ili do otpusta iz bolnice.
English: • decrease in blood pressure
Croatian: • pad krvnoga tlaka
English: Clopidogrel has been tested in a range of in vitro and in vivo genotoxicity studies, and showed no genotoxic activity.
Croatian: Klopidogrel je testiran u različitim in vivo i in vitro studijama genotoksičnosti te nije pokazao genotoksičnu aktivnost.
English: New cardiovascular events (primary endpoint) were prevented, with relative risk reductions of 22% (CI: 8.6, 33.4), 32% (CI: 12.8, 46.4), 4% (CI: -26.9, 26.7), 6% (CI: -33.5, 34.3) and 14% (CI: -31.6, 44.2), during the 0-1, 1-3, 3-6, 6-9 and 9-12 month study intervals, respectively.
Croatian: Novi su kardiovaskularni događaji (primarni ishod) spriječeni, sa smanjenjem relativnoga rizika od 22% (CI: 8,6, 33,4), 32% (CI: 12,8, 46,4), 4% (CI: -26,9, 26,7), 6% (CI: -33,5, 34,3) i 14% (CI: -31,6, 44,2) tijekom intervala ispitivanja od 0 do 1 mjesec, 1 do 3 mjeseca, 3 do 6 mjeseci, 6 do 9 mjeseci, odnosno 9 do 12 mjeseci.
English: Following therapeutic doses, approximately 10% is found excreted in the urine as salicylic acid, 75% as salicyluric acid, 10% phenolic- and 5% acyl-glucuronides of salicylic acid.
Croatian: Nakon terapijskih doza, otprilike 10% se izluči urinom u obliku salicilatne kiseline, 75% u obliku salicilurične kiseline, 10% u obliku fenolnih i 5% u obliku acil glukuronida salicilatne kiseline.
English: If you stop taking Clopidogrel/Acetylsalicylic acid Teva Do not stop the treatment unless your doctor tells you so.
Croatian: Ako prestanete uzimati Klopidogrel/acetilsalicilatna kiselina Teva Ne prekidajte liječenje osim ako Vam to ne savjetuje liječnik.
English: Merckle GmbH Ludwig-Merckle-Straße 3 89143 Blaubeuren Germany
Croatian: Merckle GmbH Ludwig-Merckle-Straße 3 89143 Blaubeuren Njemačka
English: • severe abdominal pain with or without back pain
Croatian: • jaka bol u trbuhu s bolovima u leđima ili bez njih
English: Therefore, the combination of clopidogrel/acetylsalicylic acid should be used with caution in these patients.
Croatian: Stoga je kombinaciju klopidogrela i acetilsalicilatne kiseline potrebno primjenjivati s oprezom u tih bolesnika.
English: Clopidogrel has been evaluated for safety in more than 42,000 patients who have participated in clinical studies, including over 30,000 patients treated with clopidogrel plus ASA, and over 9,000 patients treated for 1 year or more.
Croatian: Sigurnost primjene klopidogrela procijenjena je u više od 42 000 bolesnika koji su sudjelovali u kliničkim ispitivanjima, uključujući više od 30 000 bolesnika koji su liječeni klopidogrelom uz ASK, te više od 9 000 bolesnika liječenih godinu dana ili više.
English: Moreover, the safety profile of clopidogrel in this subgroup of patients did not raise any particular concern.
Croatian: Osim toga, sigurnosni profil klopidogrela nije u toj podskupini bolesnika izazvao nikakvu zabrinutost.
English: In poor metabolisers, active metabolite exposure was decreased by 63-71% compared to extensive metabolisers.
Croatian: U sporih metabolizatora, izloženost aktivnom metabolitu bila je smanjena za 6371% u usporedbi s brzim metabolizatorima.
English: • heparin or any other injectable medicine used to reduce blood clotting,
Croatian: • heparin ili bilo koji drugi lijek koji se daje injekcijom za sprječavanje zgrušavanja krvi,
English: Experimental data suggest that ibuprofen may inhibit the effect of low dose aspirin on platelet aggregation when they are dosed concomitantly.
Croatian: Eksperimentalni podaci pokazuju da ibuprofen može inhibirati učinak niske doze aspirina na agregaciju trombocita u slučaju njihove istovremene primjene.