FrancophonIA/ELRC3.0 huggingface dataset:
English: Seretide Evohaler and associated names (see Annex I) 25/250 microgram/dose pressurised inhalation, suspension.
Slovenian: Seretide Evohaler in z njim povezana imena (glejte Dodatek I) 25/250 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom.
English: Seretide Evohaler and associated names (see Annex I) 25/125 microgram/dose pressurised inhalation, suspension [See Annex I - To be completed nationally]
Slovenian: Seretide Evohaler in povezana imena (Glejte Dodatek I) 25/125 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom [Glejte Dodatek I - Izpolni država članica]
English: Seretide Evohaler and associated names (see Annex I) 25/50 microgram/dose pressurised inhalation, suspension [See Annex I - To be completed nationally]
Slovenian: Seretide Evohaler in povezana imena (Glejte Dodatek I) 25/50 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom [Glejte Dodatek I - Izpolni država članica]
English: Seretide Evohaler and associated names (see Annex I) 25/125 microgram/dose pressurised inhalation, suspension.
Slovenian: Seretide Evohaler in z njim povezana imena (glejte Dodatek I) 25/125 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom.
English: Seretide Evohaler and associated names (see Annex I) 25/250 microgram/dose pressurised inhalation, suspension [See Annex I - To be completed nationally]
Slovenian: Seretide Evohaler in povezana imena (Glejte Dodatek I) 25/250 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom [Glejte Dodatek I - Izpolni država članica]
English: Seretide Evohaler and associated names (see Annex I) 25/50 microgram/dose pressurised inhalation, suspension.
Slovenian: Seretide Evohaler in z njim povezana imena (glejte Dodatek I) 25/50 mikrogramov/odmerek, inhalacijska suspenzija pod tlakom.
English: ANNEX III
Slovenian: Dublin 16
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER [See Annex I - To be completed nationally]
Slovenian: IMETNIK DOVOLJENJA ZA PROMET [Glejte dodatek I - Izpolni država članica] {Ime in naslov} {tel.} {faks} {e-pošta}
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 120 puffs
Slovenian: VSEBNOST PO TEŽI VOLUMNU ALI ENOTI [Izpolni država članica]
English: 30 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom
Slovenian: E14E14E1430 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom
English: The European Commission granted a marketing authorisation valid throughout the European Union for Xiapex on 28 February 2011.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Xiapex, veljavno po vsej Evropski uniji, izdala 28. februarja 2011.
English: This weakens and disrupts the cord or plaque.
Slovenian: To oslabi in prekine vozlič ali plak.
English: Injection site reactions were very common, occurring in the vast majority of patients.
Slovenian: Reakcije na mestu injiciranja so bile zelo pogoste in so se pojavile pri veliki večini bolnikov.
English: What measures are being taken to ensure the safe and effective use of Xiapex?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Xiapex?
English: The full EPAR for Xiapex can be found on the Agency's website ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Xiapex je na voljo na spletni strani agencije ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: This is a summary of the European public assessment report (EPAR) for Xiapex.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Xiapex.
English: Other information about Xiapex
Slovenian: Druge informacije o zdravilu Xiapex
English: Xiapex collagenase clostridium histolyticum
Slovenian: Xiapex kolagenaza clostridium histolyticum
English: The patients were treated with three injections and their hands were examined three months after the last injection to see how much the finger joints could be straightened out.
Slovenian: Bolnike so zdravili s tremi injekcijami, njihove dlani pa so nato pregledali tri mesece po zadnjem injiciranju, da bi ugotovili, koliko se lahko sklepi prstov iztegnejo.
English: Dupuytren's contracture is a condition where one or more fingers are bent forwards toward the palm and cannot be fully straightened.
Slovenian: Dupuytrenova kontraktura je bolezen, pri kateri se en ali več prstov upogne naprej proti dlani in jih ni mogoče popolnoma iztegniti.
English: The most common side effects seen with Xiapex were local injection site reactions such as swelling, bruising, bleeding and pain.
Slovenian: Najpogostejši neželeni učinki, opaženi pri uporabi zdravila Xiapex, so lokalne reakcije na mestu injiciranja, kot so otekanje, modrice, krvavitve in bolečina.
English: A risk management plan has been developed to ensure that Xiapex is used as safely as possible.
Slovenian: Za zagotovitev čim varnejše uporabe zdravila Xiapex je bil pripravljen načrt obvladovanja tveganj.
English: The main measure of effectiveness was the proportion of patients whose main affected joint could be straightened so that it was bent forwards by no more than 5 degrees.
Slovenian: Glavno merilo učinkovitosti je bil delež bolnikov, pri katerih se je glavni prizadeti sklep lahko iztegnil tako, da ni bil upognjen naprej za več kot 5 stopinj.
English: Among patients who completed the first study, 64% (130 out of 203) of those receiving Xiapex could straighten their fingers to an angle of 5 degrees or less compared with 7% (7 out of 103) of patients receiving placebo.
Slovenian: Med bolniki, ki so zaključili prvo študijo, je 64 % (130 od 203) tistih, ki so prejemali zdravilo Xiapex, prste lahko iztegnilo do kota 5 stopinj ali manj v primerjavi s 7 % (7 od 103) bolnikov, ki so prejemali placebo.
English: The CHMP decided that Xiapex's benefits are greater than its risks and recommended that it be given marketing authorisation.
Slovenian: CHMP je zaključil, da so koristi zdravila Xiapex večje od z njim povezanih tveganj, in priporočil, da se zanj izda dovoljenje za promet.
English: These reactions were mostly mild to moderate in severity and generally subsided within one to two weeks.
Slovenian: Večinoma so bile blage do zmerne in so običajno izzvenele v enem do dveh tednih.
English: If injection and finger extension have not brought about a satisfactory response, the procedure may be repeated at monthly intervals up to a maximum of 3 injections per cord.
Slovenian: Če po enem injiciranju in iztegovanju prsta ni zadovoljivega odgovora, se postopek lahko ponovi v mesečnih razmikih do največ treh injiciranj na posamezni vozlič.
English: What benefit has Xiapex shown during the studies?
Slovenian: Kakšne koristi je zdravilo Xiapex izkazalo med študijami?
English: For more information on the use of Xiapex, including instructions on finger extension and penile modeling procedures, see the summary of product characteristics (also part of the EPAR).
Slovenian: Za več informacij o uporabi zdravila Xiapex, vključno z navodili za iztegovanje prstov in postopke oblikovanja penisa, glejte povzetek glavnih značilnosti zdravila (ki je prav tako del EPAR).
English: Around 24 hours after the injection, the finger can then be straightened by the doctor, by performing a ‘finger extension procedure' whereby it is stretched out for around 10 to 20 seconds to help disrupt the cord.
Slovenian: Približno 24 ur po injiciranju lahko zdravnik iztegne prst z izvajanjem postopka iztegovanja prstov, pri čemer prst iztegne za približno 10 do 20 sekund, da se pospeši prekinitev vozliča.
English: Patients should subsequently continue modeling procedures daily at home as instructed for the rest of the cycle.
Slovenian: Bolniki morajo nato do konca cikla postopke oblikovanja vsak dan izvajati doma v skladu z navodili.
English: The company must carry out an educational programme for doctors on the correct use and the potential side effects associated with the medicine.
Slovenian: Izvesti mora tudi izobraževalne programe za zdravnike o pravilni uporabi zdravila in možnih neželenih učinkih, povezanih z njim.
English: In each cycle, the dose of Xiapex is injected into the plaque causing the deformity followed by a second injection given 1 to 3 days after the first.
Slovenian: V vsakem ciklu se odmerek zdravila Xiapex injicira v plak, ki povzroča deformacijo, čemur sledi drugi odmerek, ki se injicira od enega do treh dni po prvem.
English: Xiapex contains a mixture of two ‘collagenases', enzymes that break up collagen.
Slovenian: Zdravilo Xiapex vsebuje mešanico dveh kolagenaz, tj. encimov, ki razgrajujejo kolagen.
English: Patients received up to 4 treatment cycles, each involving two injections and subsequent modeling procedures, and the effects were measured on follow-up after 1 year.
Slovenian: Bolniki so prejeli do štiri cikle zdravljenja, od katerih je vsak vključeval dve injiciranji in kasnejše postopke oblikovanja penisa, učinke pa so izmerili na kontrolnem pregledu po enem letu.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Xiapex.
Slovenian: Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil to zdravilo, na podlagi česar je oblikoval mnenje za izdajo dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
English: For patients with Peyronie's disease, Xiapex is given for up to 4 treatment cycles each lasting about 6 weeks.
Slovenian: Bolnikom s Peyroniejevo boleznijo se zdravilo Xiapex daje največ štiri cikle zdravljenja, od katerih vsak traja približno šest tednov.
English: Peyronie's disease is a condition in which men develop plaques of fibrous, scar-like tissue in their penis, causing it to become abnormally curved, and sometimes leading to pain or difficulty in sexual intercourse.
Slovenian: Peyroniejeva bolezen je bolezen, pri kateri se pri moškem pojavijo plaki v obliki fibroznega brazgotinastega tkiva na penisu, ki se zaradi tega nenormalno ukrivi, kar včasih povzroči bolečine ali težave pri spolnem odnosu.
English: For more information about treatment with Xiapex, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Xiapex preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: The main measures of effectiveness were the reduction in the abnormal curvature of the penis and the extent to which the condition was bothersome to the patient.
Slovenian: Glavni merili učinkovitosti sta bili zmanjšanje nenormalne ukrivljenosti penisa in ocena, kako moteča je bila bolezen za bolnika.
English: For Peyronie's disease, Xiapex was compared with placebo in two further studies involving 832 men.
Slovenian: Pri Peyroniejevi bolezni so zdravilo Xiapex primerjali s placebom v dveh dodatnih študijah, v katerih je sodelovalo 832 moških.
English: Xiapex was also more effective than placebo in treating Peyronie's disease, producing a 38% and 31% improvement in abnormal curvature in the two studies, compared with 21% and 15% respectively for placebo.
Slovenian: Zdravilo Xiapex je bilo učinkovitejše od placeba tudi pri zdravljenju Peyroniejeve bolezni, saj je v obeh študijah izboljšalo nenormalno ukrivljenost za 38 % oziroma 31 % v primerjavi z 21 % oziroma 15 % pri uporabi placeba.
English: What is the risk associated with Xiapex?
Slovenian: Kakšna tveganja so povezana z zdravilom Xiapex?
English: For the full list of all side effects and restrictions with Xiapex, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov in omejitev pri uporabi zdravila Xiapex glejte navodilo za uporabo.
English: The cords in the palm of patients with Dupuytren's contracture and the plaques in Peyronie's disease are made of fibres of a protein called collagen.
Slovenian: Vozliči v dlani bolnikov z Dupuytrenovo kontrakturo in plaki pri Peyroniejevi bolezni so iz vlaken beljakovine, imenovane kolagen.
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Xiapex, including the appropriate precautions to be followed by healthcare professionals and patients.
Slovenian: V skladu s tem načrtom so bile v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in bolniki.
English: Xiapex was compared with placebo (a dummy treatment) in two main studies involving a total of 374 adult patients with Dupuytren's contracture.
Slovenian: Zdravilo Xiapex so primerjali s placebom (zdravilom brez zdravilne učinkovine) v dveh glavnih študijah, v katerih je sodelovalo skupno 374 odraslih bolnikov z Dupuytrenovo kontrakturo.
English: The collagenases in Xiapex are extracted from the bacterium Clostridium histolyticum.
Slovenian: Kolagenazi v zdravilu Xiapex sta pridobljeni iz bakterije Clostridium histolyticum.
English: Xiapex is used to treat Dupuytren's contracture and Peyronie's disease in adults.
Slovenian: Zdravilo Xiapex se uporablja za zdravljenje Dupuytrenove kontrakture in Peyroniejeve bolezni pri odraslih.
English: Xiapex is used in patients with plaques that can be felt through the skin and in whom the abnormal curvature of the penis is at least 30 degrees at the start of therapy.
Slovenian: Zdravilo Xiapex se uporablja pri bolnikih, pri katerih je plake mogoče otipati skozi kožo in pri katerih je penis ob začetku zdravljenja nenormalno ukrivljen za vsaj 30 stopinj.
English: Xiapex is a powder and solvent that are made up into a solution for injection.
Slovenian: Zdravilo Xiapex je prašek in vehikel za pripravo raztopine za injiciranje.
English: For Dupuytren's contracture, the doctor injects the appropriate dose of Xiapex directly into a cord in the patient's palm.
Slovenian: Za zdravljenje Dupuytrenove kontrakture zdravnik injicira ustrezen odmerek zdravila Xiapex neposredno v vozlič v bolnikovi dlani.
English: Xiapex must not be used to treat Peyronie's disease if the plaque affects the urethra (the tube that carries urine and semen to the outside).
Slovenian: Zdravilo Xiapex se ne sme uporabljati za zdravljenje Peyroniejeve bolezni, če so plaki prizadeli sečnico (cevko, po kateri se izločajo seč in semenčice).
English: In the second study the figures were 44% (20 out of 45) for the Xiapex group and 5% (1 out of 21) for the placebo group.
Slovenian: V drugi študiji je bilo v skupini, ki je prejemala zdravilo Xiapex, 44 % (20 od 45) takih bolnikov v primerjavi s 5 % (1 od 21) bolnikov v skupini, ki je prejemala placebo.
English: The company that markets Xiapex must also ensure that all doctors expected to use the medicine are properly trained on the use of the medicine and experienced in diagnosing and managing Dupuytren's contracture or Peyronie's disease.
Slovenian: Poleg tega mora družba, ki izdeluje zdravilo Xiapex, zagotoviti, da so vsi zdravniki, ki naj bi uporabljali zdravilo, ustrezno usposobljeni za pravilno dajanje zdravila ter da imajo izkušnje z diagnosticiranjem in vodenjem zdravljenja Dupuytrenove kontrakture ali Peyroniejeve bolezni.
English: Xiapex was shown to be more effective at treating Dupuytren's contracture than placebo.
Slovenian: Zdravilo Xiapex se je pri zdravljenju Dupuytrenove kontrakture izkazalo za učinkovitejše od placeba.
English: A ‘penile modeling procedure' is then performed by the doctor after a further 1 to 3 days to gently stretch and bend the plaque in the opposite direction to the abnormal curvature.
Slovenian: Zdravnik nato po enem do treh dneh izvede postopek oblikovanja penisa, s katerim nežno raztegne in ukrivi plak v smeri, ki je nasprotna smeri nenormalne ukrivljenosti.
English: Why has Xiapex been approved?
Slovenian: Zakaj je bilo zdravilo Xiapex odobreno?
English: It is caused by a thickening of the tissues under the skin of the palm that form ‘cords' pulling down on the fingers.
Slovenian: Povzroča jo zadebelitev podkožnega tkiva na dlani, zaradi katere nastajajo vozliči, ki zategujejo prste.
English: It contains the active substance collagenase clostridium histolyticum.
Slovenian: Vsebuje zdravilno učinkovino kolagenazo clostridium histolyticum.
English: Xiapex must be given by a doctor trained in the use of the medicine and experienced in diagnosing and managing Dupuytren's contracture or male genital problems.
Slovenian: Zdravilo Xiapex mora dajati zdravnik, ki je ustrezno usposobljen za pravilno dajanje zdravila in ima izkušnje z diagnosticiranjem in vodenjem zdravljenja Dupuytrenove kontrakture ali težav z moškimi spolovili.
English: Xiapex is to be used in patients with cords in their palms that are thick enough to be felt through the skin.
Slovenian: Zdravilo Xiapex je namenjeno za uporabo pri bolnikih, pri katerih so vozliči v dlaneh tako veliki, da so otipljivi skozi kožo.
English: There was also a greater improvement with Xiapex than placebo in patient-reported scores of how bothersome the condition was after treatment.
Slovenian: Pri uporabi zdravila Xiapex so se bolj kot pri uporabi placeba izboljšale tudi ocene bolnikov o tem, kako moteča je bila bolezen po zdravljenju.
English: Up to 2 cords or 2 affected joints in the same hand can be treated at a time.
Slovenian: Sočasno se lahko zdravita dva vozliča ali prizadeta sklepa.
English: What is Xiapex used for?
Slovenian: Za kaj se zdravilo Xiapex uporablja?
English: How has Xiapex been studied?
Slovenian: Kako je bilo zdravilo Xiapex raziskano?
English: How does Xiapex work?
Slovenian: Kako zdravilo Xiapex deluje?
English: What is Xiapex?
Slovenian: Kaj je zdravilo Xiapex?
English: How is Xiapex used?
Slovenian: Kako se zdravilo Xiapex uporablja?
English: When injected into a cord or a plaque, the collagenases break up the collagen fibres.
Slovenian: Kolagenazi pri injiciranju v vozlič ali plak razgradita kolagenska vlakna.
English: Date of first authorisation: 10 November 2017
Slovenian: Datum prve odobritve: 10. november 2017
English: You may also see one or more air bubbles.
Slovenian: Opazite lahko tudi enega ali več zračnih mehurčkov.
English: No specific studies have been conducted in elderly patients.
Slovenian: Pri starejših bolnikih niso opravili posebnih študij.
English: Do not warm any other way.
Slovenian: Ne ogrevajte na noben drug način.
English: Wash your hands well with soap and warm water.
Slovenian: Roke si temeljito umijte z milom in toplo vodo.
English: Patients were examined at four week intervals for a total of four visits.
Slovenian: Bolnike so pregledovali s 4-tedenskimi intervali na skupno štirih obiskih.
English: • if you have an active infection, including active tuberculosis
Slovenian: • Če imate aktivno okužbo, vključno z aktivno tuberkulozo.
English: Human IgGs are known to be excreted in breast milk during the first few days after birth, and decrease to low concentrations soon afterwards; consequently, a risk to the breast-fed infant during this period cannot be excluded.
Slovenian: Znano je, da se IgG pri človeku izločajo v materino mleko v prvih dneh po rojstvu in se kmalu zatem znižajo na majhne koncentracije, zato tveganja za dojenega otroka v tem obdobju ni mogoče izključiti.
English: The following side effects are all mild to moderate.
Slovenian: Naslednji neželeni učinki so blagi do zmerni.
English: • if you think you have an infection or have symptoms of an infection (see below under ‘Look out for infections and allergic reactions')
Slovenian: • če menite, da imate okužbo ali simptome okužbe (glejte "Bodite pozorni na okužbe in alergijske reakcije"),
English: In order to improve the traceability of biological medicinal products, the name and the batch number of the administered product should be clearly recorded.
Slovenian: Zaradi boljše sledljivost bioloških zdravil je treba jasno zabeležiti ime in serijsko številko danega zdravila.
English: There may be a small amount of blood or liquid at the injection site.
Slovenian: Na mestu injiciranja se lahko pojavi manjša količina krvi ali tekočine.
English: The key efficacy results for the primary and major secondary study endpoints are shown in Table 2 below.
Slovenian: Najbolj pomembni rezultati za oceno učinkovitosti na osnovi primarnih in glavnih sekundarnih ciljev opazovanja so prikazani spodaj v Preglednici 2.
English: Percent of Subjects (%)
Slovenian: število bolnikov (%)
English: Do not remove until you are ready to inject Tremfya (See Step 2).
Slovenian: Odstranite ga šele, ko ste pripravljeni na injiciranje zdravila Tremfya (glejte korak 2).
English: Clinically important active infections (e.g., active tuberculosis, see section 4.4).
Slovenian: Klinično pomembna aktivna okužba (npr. aktivna tuberkuloza, glejte poglavje 4.4).
English: No data are available on the response to live or inactive vaccines.
Slovenian: O odzivu na živa oziroma inaktivirana cepiva ni podatkov.
English: • if you have tuberculosis or have been in close contact with someone with tuberculosis
Slovenian: • če imate tuberkulozo ali ste bili v tesnem stiku z osebo, ki ima tuberkulozo,
English: It is normal to see a drop of liquid.
Slovenian: Normalno je, da se pri tem pojavi kapljica tekočine.
English: Injection is complete when the handle is pushed all the way down, you hear a click, and the green body is no longer visible.
Slovenian: Injiciranje je zaključeno, ko je držalo potisnjeno do konca, ko zaslišite klik in ko zeleno telo ni več vidno.
English: • if you are allergic to guselkumab or any of the other ingredients of this medicine (listed in section 6).
Slovenian: • če ste alergični na guselkumab ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Comparative PASI response rates are presented in Table 6.
Slovenian: Primerjalne stopnje odziva PASI so predstavljene v Preglednici 6.
English: Place your thumb, index and middle fingers directly under the finger flange, as shown.
Slovenian: Palec, kazalec in sredinec položite tik pod držalo za prste, kot kaže slika.
English: • After the first dose, you will have the next dose 4 weeks later, and then every 8 weeks.
Slovenian: • Po prvem odmerku boste naslednji odmerek prejeli čez 4 tedne, nadaljne odmerke pa boste prejemali na vsakih 8 tednov.
English: Serious hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Slovenian: Resna preobčutljivost na učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1.
English: Push handle straight down
Slovenian: Držalo potisnite naravnost navzdol
English: Antidrug antibodies were not associated with lower efficacy or development of injection-site reactions.
Slovenian: Protitelesa proti zdravilu niso bila povezana z zmanjšano učinkovitostjo ali z razvojem reakcij na mestu injiciranja.
English: • Tremfya should not be used in pregnancy as the effects of this medicine in pregnant women are not known.
Slovenian: • Zdravila Tremfya ne smete uporabljati med nosečnostjo, ker vpliv tega zdravila pri nosečnicah ni znan.
English: Store in refrigerator at 2° to 8°C.
Slovenian: Shranjujte v hladilniku pri temperaturi od 2°C do 8°C.
English: Overall skin disease
Slovenian: Celokupno stanje kožne bolezni
English: This medicine is for single use only.
Slovenian: To zdravilo je namenjeno enkratni uporabi.
English: For further information on elimination of guselkumab, see section 5.2.
Slovenian: Za več podatkov o izločanju guselkumaba glejte poglavje 5.2.
English: Tremfya may increase the risk of infection.
Slovenian: Zdravilo Tremfya lahko poveča tveganje za razvoj okužb.
English: The adverse reactions are classified by MedDRA System Organ Class and frequency, using the following convention: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data).
Slovenian: Neželeni učinki so razvrščeni po organskih sistemih klasifikacije MedDRA in pogostnosti po naslednjem dogovoru: zelo pogosti (≥1/10); pogosti (≥1/100 do <1/10); občasni (≥1/1.000 do <1/100); redki (≥1/10.000 do <1/1.000); zelo redki (<1/10.000) in neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).