FrancophonIA/ELRC3.0 huggingface dataset:
English: Pharmacotherapeutic group: Anti-inflammatory and antirheumatic products, non-steroids (oxicams), ATCvet code: QM01AC06
Croatian: Farmakoterapijska grupa: Nesteroidni protuupalni i antireumatski proizvodi (oksikami).
English: EXPIRY DATE EXP
Croatian: ROK VALJANOSTI EXP {mjesec/godina}
English: People with known hypersensitivity to NSAIDs should avoid contact with the veterinary medicinal product.
Croatian: Ljudi s poznatom preosjetljivošću na NSAID-e ili bilo koju pomoćnu tvar trebaju izbjegavati kontakt s veterinarsko-medicinskim proizvodom.
English: People with known hypersensitivity to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) should avoid contact with the veterinary medicinal product.
Croatian: Osobe s poznatom preosjetljivošću na nesteroidne protuupalne lijekovi (NSAID) moraju izbjegavati kontakt s ovim veterinarsko-medicinskim proizvodom.
English: STATEMENT OF ACTIVE AND OTHER SUBSTANCES Each ml contains:
Croatian: I DRUGIH TVARI Svaki ml sadrži:
English: ROUTE(S) OF ADMINISTRATION Oral use.
Croatian: PUT(EVI) PRIMJENE Oralna primjena.
English: Typical adverse reactions of NSAIDs such as loss of appetite, vomiting, diarrhoea, faecal occult blood, lethargy and renal failure have occasionally been reported.
Croatian: Prijavljene su povremene tipične nuspojave NSAID-a kao što su gubitak teka, povraćanje, dijareja, nevidljivo postojanje krvi u stolici, letargija i zatajenje bubrega.
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) Meloxicam 0.5 mg/ml
Croatian: Meloxicam 0,5 mg/ml
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) Meloxicam 1.5 mg/ml
Croatian: Meloxicam 1,5 mg/ml
English: 30 ml and 150 ml presentation: amber glass bottle (type III) with polypropylene child resistant closure, polyethylene insert and clear polypropylene dosing syringe.
Croatian: Pakovanje od 30 ml i 150 ml: boca boje jantara (tip III) s polipropilenskim čepom za zaštitu od otvaranja za djecu, polietilenskim umetkom i prozirnom polipropilenskom štrcaljkom za doziranje.
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Meloxivet 1.5 mg/ml oral suspension for dogs
Croatian: NAZIV VETERINARSKO-MEDICINSKOG PROIZVODA Meloxivet 1,5 mg/ml oralna suspenzija za pse
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Meloxivet 0.5 mg/ml oral suspension for dogs
Croatian: NAZIV VETERINARSKO-MEDICINSKOG PROIZVODA Meloxivet 0,5 mg/ml oralna suspenzija za pse
English: Dosage
Croatian: KARENCIJA
English: Name and address of the manufacturer(s) responsible for batch release
Croatian: PROIZVOĐAČ ODGOVORAN ZA PUŠTANJE SERIJE U PROMET Naziv i adresa proizvođača odgovornog(ih) za puštanje serije u promet
English: For animal treatment only - to be supplied only on veterinary prescription.
Croatian: Veterinarsko-medicinski proizvod se izdaje na veterinarski recept.
English: MANUFACTURING AUTHORISATION HOLDER(S) RESPONSIBLE FOR BATCH RELEASE
Croatian: Nositelj odobrenja za proizvodnju odgovoran za puštanje serije u promet: Lusomedicamenta S.A.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/07/077/001
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE U PROMET EU/2/07/077/001
English: PACKAGE LEAFLET FOR: Meloxivet 1.5 mg/ml oral suspension for dogs
Croatian: UPUTA O VMP ZA: Meloxivet 1,5 mg/ml oralna suspenzija za pse
English: SPECIAL WARNING(S), IF NECESSARY Do not use in pregnant or lactating dogs
Croatian: KONTRAINDIKACIJE Nemojte primjenjivati Meloxivet: - ako je vaša kuja gravidna ili za vrijeme laktacije
English: PACKAGE LEAFLET FOR: Meloxivet 0.5 mg/ml oral suspension for dogs
Croatian: UPUTA O VMP ZA: Meloxivet 0,5 mg/ml oralna suspenzija za pse
English: MARKETING AUTHORISATION NUMBER(S) EU/2/07/077/003
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE U PROMET EU/2/07/077/003
English: MARKETING AUTHORISATION NUMBER(S) EU/2/07/077/005
Croatian: 16. BROJ(EVI) ODOBRENJA ZA STAVLJANJE U PROMET EU/2/07/077/005
English: 30 ml presentation: amber glass bottle (type III) with polypropylene child resistant closure, polyethylene insert and an amber polypropylene dosing syringe.
Croatian: Pakovanje od 30 ml: boca boje jantara (tip III) s polipropilenskim čepom za zaštitu od otvaranja za djecu, polietilenskim umetkom i polipropilenskom štrcaljkom za doziranje boje jantara.
English: MARKETING AUTHORISATION NUMBER(S)
Croatian: INDIKACIJA(E)
English: Absorption
Croatian: DODATAK
English: D. STATEMENT OF THE MRLs Not applicable.
Croatian: KARENCIJA Nije primjenjivo.
English: THE WORDS “KEEP OUT OF THE REACH AND SIGHT OF CHILDREN” Keep out of the reach and sight of children.
Croatian: 14. RIJEČI „ČUVATI IZVAN POGLEDA
English: Pack size bottle (HDPE) 30 tablets bottle (HDPE) 90 (3 x 30) tablets
Croatian: Kroz usta bočica (HDPE) 90 (3 x 30) tableta
English: This may lead to increased procedural complications during the operation.
Croatian: To može dovesti do povećanja proceduralnih komplikacija tijekom operacije.
English: 20148 Milan
Croatian: 20148 Milano
English: 03410 Saint Victor France
Croatian: 03410 Saint Victor Francuska
English: You may take your capsule later the same day if you have forgotten to take it earlier.
Croatian: Možete uzeti kapsulu kasnije istog dana ukoliko ste je zaboravili uzeti ranije.
English: It does not distribute into blood cells.
Croatian: Ne distribuira se u krvne stanice.
English: The absolute bioavailability is approximately 32%.
Croatian: Apsolutna bioraspoloživost iznosi približno 32%.
English: Do not give this medicine to children and adolescents below 18 years since there is no relevant indication for this age group.
Croatian: Nemojte davati ovaj lijek djeci i adolescentima u dobi manjoj od 18 godina, budući da u toj dobnoj skupini ne postoji odgovarajuća indikacija.
English: The observed effect was reversible.
Croatian: Primijećeni učinak bio je reverzibilan.
English: Tell your doctor in particular, if you take:
Croatian: Obavijestite svog liječnika osobito ako uzimate:
English: If it is almost time for the next dose, skip the dose you missed.
Croatian: Ako je uskoro vrijeme za sljedeću dozu, preskočite dozu koju ste propustili uzeti.
English: • Difficulties in getting or keeping an erection
Croatian: • poteškoće s postizanjem ili održavanjem erekcije
English: If you have taken more than one capsule, inform your doctor as soon as possible.
Croatian: Ako ste uzeli više od jedne kapsule, obavijestite čim prije svog liječnika.
English: This change is clinically not relevant and no dose adjustment is required.
Croatian: Ova promjena nije klinički važna i nije potrebno prilagođavati dozu.
English: Please inform your doctor if you are planning to have children.
Croatian: Molimo obavijestite liječnika ukoliko planirate imati djecu.
English: If you are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Croatian: Ako planirate imati dijete, od svog liječnika ili ljekarnika zatražite savjet prije nego uzmete ovaj lijek.
English: Food decreases Cmax by approximately 30%, increases tmax by approximately 1 hour and has little effect on AUC.
Croatian: Hrana smanjuje Cmax za približno 30%, povećava tmax za približno 1 sat i ima malo učinka na AUC.
English: • Decreased sexual drive
Croatian: • smanjeni spolni nagon
English: The possible side effects are listed below:
Croatian: Moguće nuspojave navedene su ispod:
English: 10 hard capsules 20 hard capsules 30 hard capsules 50 hard capsules 90 hard capsules 100 hard capsules
Croatian: 10 tvrdih kapsula 20 tvrdih kapsula 30 tvrdih kapsula 50 tvrdih kapsula 90 tvrdih kapsula 100 tvrdih kapsula
English: Difference (95% CI) vs placebo
Croatian: Razlika (95% CI) u odnosu na placebo
English: Discontinuing treatment with an α1-blocker 1-2 weeks prior to cataract surgery has been recommended, but the benefit and duration of stopping the therapy prior to cataract surgery has not yet been established.
Croatian: Preporučuje se prekid liječenja α1-blokatorom 1-2 tjedna prije operacije katarakte, ali korist i trajanje prekida terapije prije operacije katarakte još nije utvrđena.
English: • Dizziness, including dizziness when standing up (see also above, in this section)
Croatian: • omaglica, uključujući omaglicu pri ustajanju (vidjeti također gore, u istom ovom dijelu)
English: The capsule should be taken with food, preferably at the same time every day.
Croatian: Kapsulu je potrebno uzeti s hranom, po mogućnosti svaki dan u isto vrijeme.
English: The specialist can take appropriate precautions with respect to medicine and surgical techniques to be used.
Croatian: Specijalist može poduzeti odgovarajuće mjere opreza s obzirom na lijek i kiruršku tehniku koja će se koristiti.
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, carcinogenic, mutagenic and teratogenic potential.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, kancerogenosti, mutagenosti i teratogenosti.
English: Silodosin has not been evaluated in patients less than 18 years of age.
Croatian: Silodozin se nije ispitao u bolesnika mlađih od 18 godina.
English: Packs of 10, 20, 30, 50, 90, 100 capsules.
Croatian: Pakiranja od 10, 20, 30, 50, 90 i 100 kapsula.
English: Silodosin Placebo
Croatian: Silodozin Placebo
English: * p < 0.001 vs Placebo; ° p = 0.002 vs Placebo
Croatian: * p < 0,001 u odnosu na placebo; ° p = 0,002 u odnosu na placebo
English: In vitro data indicate that silodosin does not have the potential to inhibit or induce cytochrome P450 enzyme systems.
Croatian: In vitro podaci pokazuju da silodozin nema potencijal inhibirati ili inducirati sustave enzima citokroma P450.
English: Take the capsule always with food, preferably at the same time every day.
Croatian: Uvijek uzmite kapsulu s hranom, po mogućnosti svaki dan u isto vrijeme.
English: Baseline value (± SD)
Croatian: Početna vrijednost (± SD)
English: • a more frequent need to pass water, even at night.
Croatian: • učestala potreba za mokrenjem, čak i noću.
English: Orthostatic hypotension may occasionally lead to syncope (see section 4.4).
Croatian: Ortostatska hipotenzija može povremeno dovesti do sinkope (vidjeti dio 4.4).
English: At the first signs of orthostatic hypotension (such as postural dizziness), the patient should sit or lie down until the symptoms have disappeared.
Croatian: Pri prvim znakovima ortostatske hipotenzije (kao što je posturalna omaglica), bolesnik treba sjesti ili leći dok simptomi ne nestanu.
English: The incidence of orthostatic hypotension in placebo-controlled clinical studies was 1.2% with silodosin and 1.0% with placebo.
Croatian: Incidencija ortostatske hipotenzije u placebom kontroliranim kliničkim ispitivanjima bila je 1,2% uz silodozin i 1,0% uz placebo.
English: Should overdose of silodosin lead to hypotension, cardiovascular support has to be provided.
Croatian: Ako predoziranje silodozinom dovede do hipotenzije, mora se pružiti kardiovaskularna potpora.
English: In total, 1,581 patients have received silodosin at a dose of 8 mg once daily, including 961 patients exposed for at least 6 months and 384 patients exposed for 1 year.
Croatian: Ukupno je 1581 bolesnik primio silodozin u dozi od 8 mg jedanput na dan, uključujući 961 bolesnika izloženog najmanje 6 mjeseci i 384 bolesnika izloženih 1 godinu.
English: Silodosin has a volume of distribution of 0.81 L/kg and is 96.6% bound to plasma proteins.
Croatian: Silodozin ima volumen distribucije od 0,81 l/kg i 96,6% je vezan na proteine plazme.
English: • Abnormal results of liver function tests
Croatian: • abnormalni rezultati pretraga funkcije jetre
English: Exposure to silodosin and its main metabolites does not change significantly with age, even in subjects of age over 75 years.
Croatian: Starije osobe Izloženost silodozinu i njegovim glavnim metabolitima ne mijenja se značajno s dobi, čak niti u ispitanika starijih od 75 godina.
English: Results from this study should be interpreted with caution, since enrolled patients had normal biochemistry values, indicating normal metabolic function, and they were classified as having moderate liver impairment based on ascites and hepatic encephalopathy.
Croatian: Rezultate ovog ispitivanja treba tumačiti s oprezom, budući da su uključeni bolesnici imali normalne biokemijske vrijednosti koje su ukazivale na normalne metaboličke funkcije, a klasificiralo ih se kao da imaju umjereno oštećenje funkcije jetre na temelju ascitesa i hepatičke encefalopatije.
English: Consequently, the concomitant use of other α-adrenoreceptor antagonists is not recommended.
Croatian: Posljedično tome, ne preporučuje se istovremena primjena drugih antagonista α-adrenergičkih receptora.
English: Digital rectal examination and, when necessary, determination of prostate specific antigen (PSA) should be performed before treatment and at regular intervals afterwards.
Croatian: Digitorektalni pregled i, po potrebi, određivanje antigena specifičnog za prostatu (PSA) potrebno je napraviti prije liječenja i ponavljati u redovitim vremenskim razmacima nakon toga.
English: No dose adjustment is required in the elderly (see section 5.2).
Croatian: Nije potrebna prilagodba doze u starijih osoba (vidjeti dio 5.2).
English: In the long-term open-label extension phase of these controlled studies, in which patients received silodosin for up to 1 year, the symptom improvement induced by silodosin at week 12 of treatment was maintained over 1 year.
Croatian: U fazi dugotrajnog nastavka otvorenog tipa ovih kontroliranih ispitivanja u kojoj su bolesnici primali silodozin u razdoblju do 1 godine, poboljšanje simptoma izazvano silodozinom do 12. tjedna liječenja održalo se tijekom 1 godine.
English: 1 - adverse reactions from spontaneous reporting in the worldwide post-marketing experience (frequencies calculated from events reported in Phase I-IV clinical trials and non-interventional studies).
Croatian: 1 - nuspojave iz spontanih prijava u razdoblju nakon stavljanja lijeka u promet u svijetu (učestalosti su izračunate iz događaja prijavljenih u kliničkim ispitivanjima Faze I-IV i neintervencijskim ispitivanjima).
English: Positive orthostatic tests were only slightly more common during co-administration; however, no symptomatic orthostasis or dizziness occurred.
Croatian: Pozitivan nalaz na ortostatskom testu bio je tek nešto malo učestaliji tijekom istovremene primjene; međutim, nije se pojavila simptomatska ortostaza ili omaglica.
English: Not known (frequency cannot be estimated from the available data) • Floppy pupil during cataract surgery (see also above, in this section)
Croatian: Nepoznato (učestalost se ne može procijeniti iz dostupnih podataka) • meka zjenica za vrijeme operacije katarakte (pogledajte također gore, u istom ovom dijelu)
English: Blockade of these α1A-adrenoreceptors causes smooth muscle in these tissues to relax, thus decreasing bladder outlet resistance, without affecting detrusor smooth muscle contractility.
Croatian: Blokada ovih α1A-adrenergičkih receptora dovodi do opuštanja glatkih mišića u ovim tkivima i tako smanjuje otpor na izlazu iz mokraćnog mjehura, a da pritom ne utječe na kontraktilnost glatkih mišića detruzora.
English: If you do feel weak or dizzy, make sure you sit or lie down straight away until the symptoms have disappeared.
Croatian: Ako osjetite slabost ili omaglicu, odmah sjednite ili legnite dok simptomi ne nestanu.
English: If you feel that your sexual life is affected, please tell your doctor.
Croatian: Ukoliko osjećate da to utječe na Vaš seksualni život, obavijestite o tome svog liječnika.
English: • If you have problems with your kidneys, please ask your doctor for advice.
Croatian: • Ako imate tegobe s bubrezima, molimo potražite savjet liječnika.
English: This may temporarily affect male fertility.
Croatian: To može privremeno utjecati na plodnost u muškarca.
English: Minimal pharmacodynamic interactions have been observed between silodosin and maximum doses of sildenafil or tadalafil.
Croatian: Minimalne farmakodinamičke interakcije primijećene su između silodozina i maksimalnih doza sildenafila ili tadalafila.
English: IFIS (a variant of small pupil syndrome) has been observed during cataract surgery in some patients on α1-blockers or previously treated with α1-blockers.
Croatian: IFIS (inačica sindroma sužene zjenice) primijećen je tijekom operacije katarakte u nekih bolesnika koji su bili na α1-blokatorima ili su prethodno bili liječeni α1-blokatorima.
English: If you have moderate kidney problems, your doctor may prescribe a different dose.
Croatian: Ako imate umjereno teške tegobe s bubrezima, liječnik Vam može propisati drugačiju dozu.
English: Patients taking PDE-5 inhibitors concomitantly with silodosin should be monitored for possible adverse reactions.
Croatian: Bolesnici koji uzimaju inhibitore PDE-5 istovremeno sa silodozinom trebaju biti pod nadzorom zbog mogućih nuspojava.
English: Since only limited experience exists in patients with moderate renal impairment (n = 35), a lower starting dose of 4 mg is recommended.
Croatian: Budući da u bolesnika s umjerenim oštećenjem funkcije bubrega (n = 35) postoji samo ograničeno iskustvo, preporučuje se niža početna doza od 4 mg.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation:
Croatian: Datum prvog odobrenja: Datum posljednje obnove odobrenja:
English: Silodosin Recordati is available in packs containing 10, 20, 30, 50, 90, 100 capsules.
Croatian: Silodozin Recordati je dostupan u pakiranjima od 10, 20, 30, 50, 90, 100 kapsula.
English: If this occurs, make sure you sit or lie down straight away until the symptoms have disappeared and inform your doctor as soon as possible (see also section “Driving and using machines”).
Croatian: Ukoliko se to dogodi, odmah sjednite ili legnite dok simptomi ne nestanu i čim prije obavijestite svog liječnika (pogledajte također dio
English: However, a reduction in blood pressure can occur in individual patients, leading in rare cases to syncope.
Croatian: Međutim, u pojedinih bolesnika može nastupiti smanjenje krvnog tlaka i, u rijetkim slučajevima, dovesti do sinkope.
English: Silodosin was evaluated at doses of up to 48 mg/day in healthy male subjects.
Croatian: Silodozin se ispitao u dozama do 48 mg na dan u zdravih muških ispitanika.
English: Do not break or chew the capsule, but swallow it whole, preferably with a glass of water.
Croatian: Kapsulu nemojte otvarati niti žvakati, nego je progutajte cijelu, po mogućnosti uz čašu vode.
English: Silodosin 8 mg and 24 mg daily had no statistically significant effect on ECG intervals or cardiac repolarisation relative to placebo.
Croatian: Silodozin od 8 mg i 24 mg na dan nije imao statistički značajan učinak na EKG intervale i srčanu repolarizaciju u usporedbi s placebom.
English: The capsules are provided in PVC/PVDC/aluminium foil blisters, packed in cartons.
Croatian: Kapsule su dostupne u blisterima od PVC/PVDC/aluminijske folije, pakiranima u kartonske kutije.
English: • a feeling of not completely emptying the bladder,
Croatian: • osjećaj nepotpunog pražnjenja mokraćnog mjehura,
English: The European Medicines Agency has waived the obligation to submit the results of studies with the reference medicinal product containing silodosin in all subsets of the paediatric population in BPH (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove izuzela je obvezu podnošenja rezultata ispitivanja lijeka s referentnim lijekom koji sadrži silodozin u svim podskupinama pedijatrijske populacije u BHP (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: IFIS has been reported during cataract surgery (see section 4.4).
Croatian: IFIS je bio zabilježen tijekom operacije katarakte (vidjeti dio 4.4).
English: • Symptoms of allergic reaction affecting the skin like rash, itching, hives and rash caused by a medicine
Croatian: • simptomi alergijskih reakcija koje zahvaćaju kožu poput osipa, svrbeža, koprivnjače i osipa uzrokovanog lijekom
English: In male rats, decreased fertility was observed from exposures which were approximately twice the exposure at the maximum recommended human dose.
Croatian: Smanjena plodnost mužjaka štakora bila je primijećena kod razine izloženosti koja je bila približno dvostruko veća od izloženosti kod maksimalne preporučene doze u ljudi.
English: Before starting treatment, the patient should be informed that this effect may occur, temporarily affecting male fertility.
Croatian: Prije početka liječenja bolesnika treba obavijestiti o mogućoj pojavi ovog učinka koji privremeno utječe na plodnost u muškarca.
English: Exposure to the main metabolites, silodosin glucuronide and KMD3293, was also increased.
Croatian: Izloženost glavnim metabolitima, silodozin glukuronidu i KMD3293, također je bila povećana.
English: SPECIAL STORAGE CONDITIONS Do not store above 30 °C.
Croatian: POSEBNE MJERE ČUVANJA Ne čuvati na temperaturi iznad 30 °C.
English: Dialysis is unlikely to be of significant benefit since silodosin is highly (96.6%) protein bound.
Croatian: Dijaliza najvjerojatnije neće biti od značajne koristi budući da se silodozin veže za proteine u visokom postotku (96,6%).
English: The responder rate (i.e. improvement in the IPSS total score by at least 25%) was significantly higher in the silodosin (68%) and tamsulosin group (65%), as compared to placebo (53%).
Croatian: Stopa terapijskog odgovora (tj. poboljšanje ukupnog IPSS rezultata za najmanje 25%) bila je značajno viša u skupini koja je primala silodozin (68%) i skupini koja je primala tamsulozin (65%) u usporedbi s placebom (53%).
English: Contact your doctor immediately if you notice any of the following allergic reactions: swelling of the face or throat, difficulty in breathing, feeling faint, itchy skin or hives since the consequences could become serious.
Croatian: Ako primijetite neku od sljedećih alergijskih reakcija: oticanje lica ili grla, otežano disanje, osjećaj nesvjestice, svrbež kože ili koprivnjača, odmah se obratite svom liječniku jer posljedice mogu postati ozbiljne.
English: Effects in animals (affecting the thyroid gland in rodents) were observed only at exposures considered sufficiently in excess of the maximum human exposure, indicating little relevance to clinical use.
Croatian: Učinci na životinjama (koji su zahvaćali štitnu žlijezdu u glodavaca) bili su primijećeni samo pri izloženosti koja se smatrala dovoljno većom od maksimalne izloženosti kod ljudi, ukazujući na malu važnost za kliničku primjenu.
English: Silodosin Recordati is used in adult men to treat the urinary symptoms associated with benign enlargement of the prostate (prostatic hyperplasia), such as:
Croatian: Silodozin Recordati se primjenjuje u odraslih muškaraca za liječenje urinarnih simptoma povezanih s dobroćudnim povećanjem prostate (hiperplazija prostate), kao što su:
English: In the subjects over 65 years, the mean decreases at the various time points were between 5 and 15 mmHg (systolic) and 0 and 10 mmHg (diastolic).
Croatian: ispitanika starijih od 65 godina, srednje vrijednosti smanjenja u različitim vremenskim točkama bile su između 5 i 15 mmHg (sistolički) i 0 i 10 mmHg (dijastolički).
English: Concomitant use with potent CYP3A4 inhibitors (such as ketoconazole, itraconazole, ritonavir or cyclosporine) is not recommended.
Croatian: Ne preporučuje se istovremena primjena s jakim inhibitorima CYP3A4 (kao što su ketokonazol, itrakonazol, ritonavir ili ciklosporin).
English: Silodosin administered orally is well absorbed and absorption is dose proportional.
Croatian: Silodozin primijenjen peroralno dobro se apsorbira, a apsorpcija je proporcionalna dozi.
English: This makes it easier for you to pass water and relieves your symptoms.
Croatian: To olakšava mokrenje i ublažava simptome.
English: The capsule should not be broken or chewed but swallowed whole, preferably with a glass of water.
Croatian: Kapsula se ne smije otvarati niti žvakati, nego se mora progutati cijela, po mogućnosti s čašom vode.
English: Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) in adult men.
Croatian: Liječenje znakova i simptoma benigne hiperplazije prostate (BHP) u odraslih muškaraca.
English: If you stop treatment, your symptoms may re-appear.
Croatian: Ako prekinete liječenje, simptomi