FrancophonIA/ELRC3.0 huggingface dataset:
English: Each bottle contains 1.55 ml (6,200 micrograms fentanyl)
Croatian: Jedna bočica sadrži 1,55 ml (6200 mikrograma fentanila).
English: The concomitant use of other central nervous system depressants, including other opioids, sedatives or hypnotics, general anaesthetics, phenothiazines, tranquillisers, skeletal muscle relaxants, sedating antihistamines and alcohol may produce additive depressant effects.
Croatian: Istodobna primjena drugih depresora središnjeg živčanog sustava, uključujući druge opioide, sedative ili hipnotike, opće anestetike, fenotiazine, lijekove za smirenje, lijekove za opuštanje skeletnih mišića, sedirajuće antihistaminike i alkohol, može izazvati dodatne depresorske učinke.
English: This is because it may then give you the wrong dose.
Croatian: Na taj bi način sprej mogao raspršiti krivu dozu.
English: • You will need to press down and release the finger grips 4 more times while aiming the nasal spray away from you (and any other people).
Croatian: • Zato ćete morati pritiskati i otpuštati pritisak još dodatna 4 puta, s tim da sprej i dalje bude okrenut od Vas (i drugih osoba).
English: Following long-term treatment, fentanyl may cause withdrawal in the new-born infant.
Croatian: Nakon dugotrajnog liječenja fentanil može u novorođenčeta uzrokovati simptome ustezanja.
English: Dose-proportionality was demonstrated for Cmax and area under the curve (AUC) in the dose range 100 micrograms to 800 micrograms (see Figure 3).
Croatian: Proporcionalnost doza dokazana je za Cmax i površinu ispod krivulje (AUC) u rasponu doza od 100 mikrograma do 800 mikrograma (vidjeti sliku 3).
English: Cardiac disease
Croatian: Bolest srca
English: Finding the right dose
Croatian: Određivanje odgovarajuće doze
English: • Do not use for more than 60 days after first use (either priming or using to treat a breakthrough pain episode).
Croatian: • Ne upotrebljavajte lijek ako je od prve upotrebe prošlo više od 60 dana (bilo da ste tada bočicu aktivirali ili je upotrijebili za liječenje epizode probijajuće boli).
English: • Do not use for more than 5 days after first use (either priming or using to treat a breakthrough pain episode).
Croatian: • Ne upotrebljavajte lijek ako je od prve upotrebe prošlo više od 5 dana (bilo da ste tada bočicu aktivirali ili je upotrijebili za liječenje epizode probijajuće boli).
English: You will hear a second ‘click' and there should now be a single large red bar in the counting window (Figure 3b).
Croatian: Čut ćete drugi 'klik' i tada bi se u prozorčiću s brojačem trebala pojaviti široka crvena crta (slika 3b).
English: The PecFent spray droplets form a gel in the nose.
Croatian: Kapljice raspršenog PecFenta u nosu oblikuju gel.
English: A pharmacokinetic study was conducted to evaluate the absorption and tolerability of a single dose of PecFent in patients with pollen-induced seasonal allergic rhinitis, comparing the un-challenged, acutely challenged (rhinitic) and acutely challenged and then treated with oxymetazoline, states.
Croatian: Provedeno je farmakokinetičko ispitivanje kako bi se procijenile apsorpcija i podnošljivost jednokratne doze PecFenta u bolesnika sa sezonskim alergijskim rinitisom izazvanim peludom pri čemu se uspoređivalo neprovocirano stanje, akutno provocirano stanje (rinitično) i akutno provocirano stanje koje je zatim liječeno oksimetazolinom.
English: Although muscle rigidity interfering with respiration has not been seen following the use of PecFent, this is possible with fentanyl and other opioids.
Croatian: Iako za vrijeme primjene PecFenta nije opaženo da mišićna rigidnost ometa disanje, to je moguće uz fentanil i druge opioide.
English: • Do not drink grapefruit juice while using PecFent.
Croatian: • Ne pijte sok od grejpa dok se liječite PecFentom.
English: Disposition of fentanyl following intranasal administration of PecFent has not been characterised in a mass balance study.
Croatian: Eliminacija Uklanjanje fentanila nakon nazalne primjene PecFenta nije bilo detaljno opisano u ispitivanju masene bilance.
English: As with other opioids, in case of insufficient pain control in response to an increased dose of fentanyl, the possibility of opioid-induced hyperalgesia should be considered.
Croatian: Hiperalgezija Kao i kod drugih opioida, u slučaju da kontrola boli kao odgovor na povišenu dozu fentanila nije zadovoljavajuća, potrebno je razmotriti vjerojatnost razvoja hiperalgezije izazvane opioidima.
English: Dehydration Hyperglycaemia Decreased appetite Increased appetite
Croatian: Poremećaji metabolizma i prehrane dehidracija hiperglikemija oslabljen apetit pojačan apetit
English: Relative bioavailability of fentanyl from the PecFent treatment compared to the 200 microgram OTFC was approximately
Croatian: Relativna bioraspoloživost fentanila u liječenju PecFentom u usporedbi s 200 mikrograma OTFC bila je otprilike 120%.
English: Put the nozzle a short distance (about 1 cm) into your nostril.
Croatian: Gurnite mlaznicu u nosnicu (oko 1 cm).
English: • The initial dose of PecFent to treat episodes of BTP is always 100 micrograms (one spray), even in patients switching from other fentanyl containing products for their BTP.
Croatian: • Početna doza PecFenta za liječenje epizoda probijajuće boli uvijek je 100 mikrograma (jedan potisak), čak i u bolesnika koji za liječenje probijajuće boli prelaze s nekog drugog lijeka koji sadrži fentanil.
English: In severe cases taking too much PecFent may also lead to coma.
Croatian: U teškim slučajevima, primjena prevelike količine lijeka PecFent može dovesti i do kome.
English: There are still doses of PecFent left in the bottle.
Croatian: To znači da je u bočici preostalo još doza lijeka PecFent.
English: The pump has a spray counter that clicks, so you can hear as well as see that the spray has been given.
Croatian: Pumpica ima brojač doza koji stvara čujni klik pri raspršivanju doze, tako da možete i čuti i vidjeti kad je doza primijenjena.
English: As you repeat step 5, the red bar will become smaller and smaller until you see a green bar in the counting window (Figure 3b-e).
Croatian: Kako ponavljate 5. korak, crvena crta postajat će sve tanja dok se konačno u prozorčiću s brojačem ne pojavi zelena crta (slika 3b-e).
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a signficant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached.
Croatian: • Uoči svake izmjene sustava za upravljanje rizikom, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik,
English: • get cold clammy skin, look pale, have a weak pulse or other signs of shock.
Croatian: • koža Vam je postala hladna i ljepljiva, blijedi ste, imate slabi puls ili neke druge znakove šoka.
English: • Severe breathing problems
Croatian: • teški problemi s disanjem
English: Uncommon side effects: (may affect up to 1 in 100 people):
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na svakih 100 osoba):
English: PecFent may interact with these medicines and you may experience mental status changes (e.g. agitation, hallucinations, coma), and other effects such as body temperature above 38°C, increase in heart rate, unstable blood pressure, and exaggeration of reflexes,
Croatian: PecFenta s tim lijekovima i mogli biste doživjeti promjene mentalnog statusa (npr. nemir, halucinacije, komu) i druge posljedice kao što su povišenje tjelesne temperature iznad 38°C, ubrzani otkucaji srca, nestabilan krvni tlak,
English: PecFent bottles in their child resistant containers are supplied in cartons containing 1, 4 or 12 bottles.
Croatian: Bočice lijeka PecFent i njihovi spremnici sigurni za djecu dobivaju se u kutijama koje mogu sadržavati 1, 4 ili 12 bočica.
English: When you see the number “2” in the counting window, there is still medicine in the bottle that you must empty.
Croatian: Kada se u prozorčiću brojača pojavi broj “2“, i dalje u bočici ima nešto lijeka koji morate isprazniti.
English: • swelling of the soft tissue
Croatian: • oticanje mekog tkiva
English: Treatment should be initiated by and remain under the supervision of a physician experienced in the management of opioid therapy in cancer patients.
Croatian: Liječenje mora započeti i nadzirati liječnik s iskustvom u primjeni opioidne terapije u bolesnika s rakom.
English: Superiority was demonstrated by the primary endpoint, Pain Intensity Difference within 15 minutes, which was 3.02 in patients treated with PecFent compared to 2.69 in patients treated with IRMS (p=0.0396).
Croatian: Superiornost je dokazana primarnim ishodom, razlikom intenziteta bola unutar 15 minuta, koja je u bolesnika liječenih PecFentom iznosila 3,02 u usporedbi s 2,69 u bolesnika liječenih morfin sulfatom s trenutačnim otpuštanjem (p=0,0396).
English: Any empty bottles should be returned to their child resistant container and discarded by taking them back to the pharmacy or according to local requirements.
Croatian: Sve prazne bočice mora se staviti u njihove spremnike sigurne za djecu i vratiti u ljekarnu ili zbrinuti prema lokalnim propisima.
English: 8 spray bottle:
Croatian: Bočica sa 8 potisaka:
English: Titration in patients switching between immediate-release fentanyl containing products Substantial differences may exist in the pharmacokinetic profile of immediate-release fentanyl medicinal products, which result in clinically important differences in the rate and extent of absorption of fentanyl.
Croatian: Među lijekovima s trenutačnim otpuštanjem fentanila mogu postojati znatne razlike u farmakokinetičkom profilu, što rezultira klinički važnim razlikama u brzini i opsegu apsorpcije fentanila.
English: Bottles in their child resistant containers are supplied in cartons containing: For 2 spray bottle: 1 bottle.
Croatian: Bočice i njihovi spremnici sigurni za djecu isporučuju se u kutijama koje mogu sadržavati: Za bočicu sa 2 potiska: 1 bočicu.
English: This is because it may cause breathing problems in your baby.
Croatian: To bi moglo prouzročiti teškoće s disanjem u Vašeg novorođenčeta.
English: When you see the number “8” in the counting window, there is still medicine in the bottle that you must empty.
Croatian: Kada se u prozorčiću brojača pojavi broj „8“, i dalje u bočici ima nešto lijeka koji morate isprazniti.
English: The number counter will move forward after each use and show how many sprays have been used.
Croatian: Broj u prozorčiću brojača poveća se poslije svake primjene i pokazuje Vam koliko ste doza uzeli.
English: [2 spray bottle:] If the spray has not been used within 5 days after priming it should be discarded.
Croatian: [Bočica sa 2 potiska:] Ako sprej nije upotrebljavan u roku od 5 dana od aktiviranja treba ga baciti.
English: PecFent can deliver 100, 200, 400 and 800 microgram doses as follows:
Croatian: Primjenom PecFenta mogu se postići doze od 100, 200, 400 i 800 mikrograma, kako slijedi: Potrebna doza (mikrogrami)
English: • being less aware or responsive, losing consciousness
Croatian: • manje ste svjesni ili slabije reagirate, gubite svijest • konvulzije (napadaji)
English: Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain.
Croatian: Probijajuća bol je prolazna egzacerbacija boli koja se dodatno javlja uz već kontroliranu upornu dugotrajnu bol.
English: One dose of PecFent may include administration of 1 spray (100 microgram or 400 microgram doses) or 2 sprays (200 microgram or 800 microgram doses) of the same strength (either 100 microgram or 400 microgram strength).
Croatian: 400 mikrograma) ili 2 potiska spreja (doza od 200 mikrograma ili 800 mikrograma) iste jačine (jačina ili 100 mikrograma ili 400 mikrograma).
English: EU/1/10/644/007 100 micrograms, 2 sprays, 1 bottle EU/1/10/644/001 100 micrograms, 8 sprays, 1 bottle EU/1/10/644/002 100 micrograms, 8 sprays, 4 bottles EU/1/10/644/005 100 micrograms, 8 sprays, 12 bottles
Croatian: EU/1/10/644/007 100 mikrograma, 2 potiska, 1 bočica EU/1/10/644/001 100 mikrograma, 8 potisaka, 1 bočica EU/1/10/644/002 100 mikrograma, 8 potisaka, 4 bočica EU/1/10/644/005 100 mikrograma, 8 potisaka, 12 bočica
English: For treatment of overdose in opioid-maintained patients, intravenous access should be obtained.
Croatian: Za liječenje predoziranja u bolesnika koji primaju terapiju održavanja opioidima nužno je pripremiti intravenski pristup.
English: This is because it may affect the way in which your body breaks down the medicine.
Croatian: To može utjecati na način na koji Vaše tijelo razgrađuje lijek PecFent.
English: Therefore, when switching between fentanyl containing medicinal products indicated for treatment of breakthrough pain, including intranasal formulations, it is essential that patients are again titrated with the new medicinal product, and not switched on a dose-for-dose (microgram-formicrogram) basis.
Croatian: Stoga je pri prelaženju s jednog lijeka s fentanilom indiciranog za liječenje probijajuće boli na drugi takav lijek, uključujući intranazalne pripravke, bitno bolesnike ponovno titrirati za taj novi lijek, a ne zamijeniti lijekove po načelu doza za dozu (mikrogram za mikrogram).
English: Do not use more than the dose that your doctor prescribes to treat any single pain episode.
Croatian: Nemojte primijeniti više od doze koju Vam je liječnik propisao za bilo koju pojedinačnu epizodu probijajuće boli.
English: PecFent should be administered with caution to patients with moderate or severe hepatic or renal impairment (see section 4.4).
Croatian: Oštećenje jetre ili bubrega PecFent se mora primjenjivati s oprezom u bolesnika s umjerenim ili teškim oštećenjem jetre ili bubrega (vidjeti dio 4.4).
English: Wipe the nozzle with a tissue and flush the tissue down the toilet.
Croatian: Obrišite mlaznicu papirnatom maramicom i bacite maramicu u zahod.
English: The concomitant use of PecFent with strong CYP3A4 inhibitors (e.g. ritonavir, ketoconazole, itraconazole, troleandomycin, clarithromycin, and nelfinavir) or moderate CYP3A4 inhibitors (e.g. amprenavir, aprepitant, diltiazem, erythromycin, fluconazole, fosamprenavir, grapefruit juice, and verapamil) may result in increased fentanyl plasma concentrations, potentially causing serious adverse drug reactions including fatal respiratory depression.
Croatian: Istodobna primjena PecFenta i jakih inhibitora CYP3A4 (npr. ritonavir, ketokonazol, itrakonazol, troleandomicin, klaritromicin i nelfinavir) ili umjerenih inhibitora CYP3A4 (npr. amprenavir, aprepitant, diltiazem, eritromicin, flukonazol, fosamprenavir, sok od grejpa i verapamil) može rezultirati povećanim koncentracijama fentanila u plazmi što bi moglo prouzročiti ozbiljne nuspojave uključujući respiratornu depresiju sa smrtnim ishodom.
English: fentanyl, oxycodone or hydromorphone) to control your constant background pain.
Croatian: oksikodon ili hidromorfon) protiv stalno prisutnih bolova.
English: • Do not use this medicine after the expiry date which is stated on the carton and bottle after EXP.
Croatian: • Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici iza
English: • you suffer from recurrent nose bleeding - he may advise an alternative treatment
Croatian: • ako Vam se događaju ponavljana krvarenja iz nosa - u tom slučaju liječnik Vam može preporučiti zamjensko liječenje
English: • you have breathing problems such as asthma, wheezing or shortness of breath
Croatian: • ako imate tegobe povezane s disanjem kao što su astma, piskanje ili nedostatak zraka
English: If you can see a number, other than 8 in the counting window, you have NOT used all 8 sprays in the bottle.
Croatian: • Ako u prozorčiću brojača vidite neki drugi broj a ne broj 8, to znači da NISTE primijenili svih 8 potisaka iz bočice.
English: The clinical studies of PecFent were designed to evaluate safety and efficacy in treating BTP and all patients were also on background opioid therapies, such as sustained-release morphine or transdermal fentanyl, for their persistent pain.
Croatian: PecFenta bila su osmišljena kako bi se procijenila njegova sigurnost i djelotvornost u liječenju probijajuće boli, a svi su bolesnici protiv uporne boli primali i osnovne opioidne terapije kao što su morfin s produženim otpuštanjem ili transdermalni fentanil.
English: The development of a potentially life-threatening serotonin syndrome may occur with the concomitant use of serotonergic medicinal products such as Selective Serotonin Re-uptake Inhibitors (SSRIs) and Serotonin Norepinephrine Re-uptake Inhibitors (SNRIs), and with medicinal products which impair metabolism of serotonin (including Monoamine Oxidase Inhibitors [MAOIs]).
Croatian: Do razvoja serotoninskog sindroma potencijalno opasnog po život može doći pri istodobnoj primjeni serotoninergičkih lijekova kao što su selektivni inhibitori ponovne pohrane serotonina (SSRI) ili selektivni inhibitori ponovne pohrane serotonina i noradrenalina (SNRI) te lijekova koji narušavaju metabolizam serotonina (uključujući inhibitore monoaminooksidaze [MAOI]).
English: 8 spray bottle: If the product has not been used for 5 days, it should be re-primed by spraying once.
Croatian: Bočica sa 8 potisaka: Ako lijek nije upotrebljavan 5 dana, bočicu treba ponovno aktivirati jednim raspršivanjem.
English: • feeling sleepy, headache
Croatian: • osjećaj pospanosti, glavobolja
English: • If you are an athlete, using PecFent may result in positive doping-tests.
Croatian: • Ako ste sportaš, primjena PecFenta može utjecati na Vaše rezultate testova na nedozvoljene tvari (doping testovi) i oni mogu biti pozitivni.
English: PecFent is available in two strengths: 100 micrograms/spray and 400 micrograms/spray.
Croatian: PecFent je dostupan u dvije jačine: 100 mikrograma/potisak i 400 mikrograma/potisak.
English: • numbness or tingling in the mouth , tongue, or nose, or other tongue problems, mouth ulcers, dry mouth
Croatian: • puknuće crijeva ili upala želučane sluznice • utrnulost ili trnci u ustima, jeziku ili nosu, ili druge tegobe s jezikom, čirevi u ustima, suha usta
English: The bottle must be primed before first use by holding upright and simply pressing and releasing the finger grips either side of the nozzle until a green bar appears in the counting window (should occur after four sprays).
Croatian: Prije prve upotrebe bočicu se mora 'aktivirati' i to tako da se drži u uspravnom položaju i jednostavno pritišće i otpušta potisni dio s jedne i druge strane mlaznice, sve dok se u prozorčiću s brojačem doza ne pokaže zelena crta (morala bi se pojaviti nakon četiri potiska).
English: PecFent comes in two different strengths: a 100 microgram per spray bottle and a 400 microgram per spray bottle.
Croatian: PecFent se isporučuje u dvije različite jačine: 100 mikrograma po bočici spreja i 400 mikrograma po bočici spreja.
English: In a long-term, open-label, safety study (Study 045), 355 patients entered the 16-week treatment phase, during which 42,227 episodes of breakthrough cancer pain (BTP) were treated with PecFent.
Croatian: U dugotrajnom, otvorenom ispitivanju sigurnosti (ispitivanje 045), 355 bolesnika uključeno je u fazu liječenja od 16 tjedana, a za vrijeme te faze 42 227 epizoda probijajuće boli uzrokovane karcinomom liječeno je PecFentom.
English: • The PecFent nasal spray dose strengths can not be compared with other PecFent products
Croatian: o Jačine doza PecFent spreja za nos ne mogu se usporediti s drugim PecFent lijekovima.
English: 1 bottle - 1.55 ml (8 sprays) per bottle 4 bottles - 1.55 ml (8 sprays) per bottle 12 bottles 1.55 ml (8 sprays) per bottle
Croatian: 1 bočica - 1,55 ml (8 potisaka) po bočici 4 bočice - 1,55 ml (8 potisaka) po bočici 12 bočica - 1,55 ml (8 potisaka) po bočici
English: • heat and circulation not working properly, hot flush or fever, chills, excessive sweating
Croatian: • poremećena tjelesna toplina i cirkulacija, navala vrućine ili vrućica, zimica, prekomjerno znojenje
English: PecFent should be titrated to an “effective” dose that provides adequate analgesia and minimises adverse reactions without causing undue (or intolerable) adverse reactions, for two consecutively treated episodes of BTP.
Croatian: PecFent se mora titrirati na “djelotvornu” dozu, koja u dvije uzastopne epizode probijajuće boli pruža odgovarajuću analgeziju i umanji nuspojave bez uzrokovanja pretjeranih (ili nepodnošljivih)
English: • Do not use more than the dose your doctor prescribes for any single breakthrough pain episode.
Croatian: • Nemojte primijeniti više od doze koju Vam je liječnik propisao za bilo koju pojedinačnu epizodu probijajuće boli.
English: Using PecFent PecFent is only to be used by spraying into your nostril.
Croatian: Primjena lijeka PecFent PecFent treba upotrijebiti samo raspršivanjem u nosnicu.
English: This is because PecFent could be life-threatening if taken by a child by accident.
Croatian: To je važno zato što PecFent može ugroziti život djeteta ako ga ono nehotice primijeni.
English: • The prescribers of PecFent nasal spray must critically select the patients and closely follow o Instructions for use of the nasal spray device o Instructions for opening and closing of the child-resistant box o Information on the correct indication
Croatian: Propisivači PecFent spreja za nos moraju kritički pristupiti izboru bolesnika i pažljivo slijediti upute za primjenu spreja za nos upute za otvaranje i zatvaranje kutije sigurne za djecu podatke o pravilnoj indikaciji o PecFent sprej za nos ne smije se koristiti za liječenje nekih drugih kratkotrajnih bolova ili bolnih stanja.
English: EU/1/10/644/003 400 micrograms, 8 sprays, 1 bottle EU/1/10/644/004 400 micrograms, 8 sprays, 4 bottles EU/1/10/644/006 400 micrograms, 8 sprays, 12 bottles
Croatian: EU/1/10/644/003 400 mikrograma, 8 potisaka, 1 bočica EU/1/10/644/004 400 mikrograma, 8 potisaka, 4 bočice EU/1/10/644/006 400 mikrograma, 8 potisaka, 12 bočica
English: Concomitant use of nasally administered oxymetazoline has been shown to decrease the absorption of PecFent (see section 5.2).
Croatian: Dokazano je da istodobna nazalna primjena oksimetazolina smanjuje apsorpciju PecFenta (vidjeti dio
English: 0.95 ml - 2 sprays 1.55 ml - 8 sprays
Croatian: 0,95 ml - 2 potiska 1,55 ml - 8 potisaka
English: Serotonin syndrome may include mental-status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular abnormalities (e.g., hyperreflexia, incoordination, rigidity), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhoea).
Croatian: Serotoninski sindrom može uključivati promjene mentalnog statusa (npr. agitaciju, halucinacije, komu), autonomnu nestabilnost (npr. tahikardiju, nestabilan krvni tlak, hipertermiju), neuromuskularne poremećaje (npr. hiperrefleksiju, nekoordiniranost, rigidnost) i/ili gastrointestinalne simptome (npr. mučninu, povraćanje, proljev).
English: What you need to know before you use PecFent Do not use PecFent if:
Croatian: Što morate znati prije nego počnete primjenjivati PecFent
English: A spray is then administered by pressing and releasing the finger grips either side of the nozzle.
Croatian: Zatim se primijeni potisna doza pritiskanjem i otpuštanjem potisnog dijela s jedne i druge strane mlaznice.
English: PecFent contains propylparahydroxybenzoate (E216).
Croatian: PecFent sadrži propilparahidroksibenzoat (E216).
English: • Withdrawal syndrome (may manifest by the occurrence of the following side effects nausea,
Croatian: • sindrom ustezanja (može se očitovati pojavom sljedećih nuspojava: mučnina, povraćanje,
English: • When you see the red 2 in the counting window, the bottle is finished and you will no longer be able to get a full spray from it.
Croatian: • Kada u prozorčiću brojača ugledate crveni broj 2, bočica je iskorištena i iz nje više nećete moći istisnuti punu dozu raspršenog lijeka.
English: 0.95 ml (950 micrograms fentanyl) - 2 spray bottle or
Croatian: 0,95 ml (950 mikrograma fentanila) - bočica sa 2 potiska ili