FrancophonIA/ELRC3.0 huggingface dataset:
English: One transfer device.
Slovenian: Ena naprava za prenos.
English: • transport in the desert (4 days submitted to temperatures ranging from 5 to 60°C) and
Slovenian: • prevoz v puščavi (4 dni izpostavljenosti temperaturam od 5 °C do 60 °C) in
English: If blood products (whole blood, packed red cells, platelet concentrate and fresh frozen plasma) and hydroxocobalamin are administered simultaneously, use of separate intravenous lines (preferably on contralateral extremities) is recommended.
Slovenian: Če sočasno uporabljate krvne izdelke (polno kri, koncentrat eritrocitov, koncentrat trombocitov in sveže zamrznjeno plazmo) in hidroksokobalamin, je priporočena uporaba ločenih intravenskih linij (po možnosti na nasprotnih okončinah).
English: Urine colouration may last up to 35 days after administration of Cyanokit (see section 4.4).
Slovenian: Obarvanje urina lahko traja do 35 dni po uporabi zdravila Cyanokit (glejte poglavje 4.4).
English: Cyanokit may interfere with burn assessment (red coloration of the skin) and laboratory tests and may lead to shut down of haemodialysis machines (see SmPC).”
Slovenian: Zdravilo Cyanokit lahko moti ocenjevanje stopnje opeklin (povzroči rdeče obarvanje kože) in rezultate laboratorijskih preiskav in lahko povzroči, da se aparature za hemodializo izklopijo (glejte povzetek glavnih značilnosti zdravila).”
English: Cyanide poisoning may be caused by exposure to smoke from household and industrial fires, breathing or swallowing cyanide, or contact with cyanide on skin.
Slovenian: Zastrupitev s cianidom lahko povzroči izpostavljenost dimu pri požarih v gospodinjstvu in industriji, vdihovanje ali zaužitje cianida ali stik s cianidom prek kože.
English: Each pack contains one vial packed in one cardboard box, one sterile transfer device, one sterile intravenous infusion set and one sterile short catheter for administration to children.
Slovenian: V enem pakiranju je ena viala, pakirana v eno kartonsko škatlo, ena sterilna naprava za prenos, en sterilen komplet za intravensko infundiranje in en sterilen kratek kateter za uporabo pri otrocih.
English: Each hydroxocobalamin molecule can bind one cyanide ion by substituting the hydroxo ligand linked to the trivalent cobalt ion to form cyanocobalamin.
Slovenian: Vsaka molekula hidroksokobalamina lahko veže en cianidni ion ob substituciji hidrokso-liganda, ki je vezan na trivalentni kobaltov ion, pri čemer nastane cianokobalamin.
English: However, skin lesions, oedema, and pain are highly suggestive of burns.
Slovenian: Vendar so za opekline zelo značilne kožne lezije, edem in bolečina.
English: However, hydroxocobalamin because of its deep red colour may interfere with the performance of haemodialysis machines (see section 4.4).
Slovenian: Vendar pa lahko hidroksokobalamin zaradi svoje temno rdeče barve moti delovanje aparatur za hemodializo (glejte poglavje 4.4).
English: In the absence of data in breast-fed infants, breast-feeding discontinuation is recommended after receiving Cyanokit.
Slovenian: Ker ni na voljo podatkov pri dojenih otrocih, se po uporabi zdravila Cyanokit priporoča prekinitev dojenja.
English: Physical incompatibility (particle formation) was observed with the mixture of hydroxocobalamin reconstituted solution and the following medicinal products: diazepam, dobutamine, dopamine, fentanyl, nitroglycerin, pentobarbital, phenytoin sodium, propofol and thiopental.
Slovenian: Fizikalno inkompatibilnost (nastanek delcev) so opazili pri mešanju rekonstituirane raztopine hidroksokobalamina in naslednjih zdravil: diazepam, dobutamin, dopamin, fentanil, nitroglicerin, pentobarbital, natrijev fenitoin, propofol in tiopental.
English: However, if a cyanide blood level determination is planned, it is recommended to draw the blood sample before initiation of treatment with Cyanokit.
Slovenian: Če pa se načrtuje določanje ravni cianida v krvi, je priporočeno odvzeti vzorec krvi pred začetkom zdravljenja z zdravilom Cyanokit.
English: In cyanide-poisoned patients, hydroxocobalamin is expected to bind cyanide to form cyanocobalamin, which is excreted in the urine.
Slovenian: Pri bolnikih, zastrupljenih s cianidom, je pričakovati, da bo hidroksokobalamin vezal cianid, pri čemer bo nastal cianokobalamin, ki se izloča z urinom.
English: Smoke inhalation
Slovenian: Vdihavanje dima
English: • The active substance is hydroxocobalamin.
Slovenian: • Zdravilna učinkovina je hidroksokobalamin.
English: monitoring of renal function: Cyanokit may lead to kidney failure and urine crystals.
Slovenian: spremljanje delovanja ledvic: zdravilo Cyanokit lahko povzroči odpoved ledvic in kristale v urinu.
English: • most patients will experience a reversible red colouration of the skin and membranes lining body cavities (mucous membranes) that may last up to 15 days after administration of Cyanokit.
Slovenian: • pri večini bolnikov se bo pojavilo reverzibilno rdeče obarvanje kože in sluznic telesnih votlin, ki lahko traja do 15 dni po uporabi zdravila Cyanokit
English: The liver and kidney were found to be the major target organs.
Slovenian: Ugotovili so, da sta glavna ciljna organa jetra in ledvice.
English: Breathing and chest problems
Slovenian: Težave pri dihanju in težave v prsnem košu
English: If a cyanide blood level determination is planned, it is recommended to draw the blood sample before initiation of treatment with Cyanokit.
Slovenian: Če se načrtuje določanje ravni cianida v krvi, je priporočeno odvzeti vzorec krvi pred začetkom zdravljenja z zdravilom Cyanokit.
English: • The other ingredient is hydrochloric acid (for pH adjustment).
Slovenian: • Druga sestavina zdravila je klorovodikova kislina (za uravnavanje pH).
English: Detailed information for your doctor or other health care professional regarding simultaneous administration of Cyanokit with other medicines can be found at the end of this package leaflet (see 'Handling instructions').
Slovenian: Podrobne informacije za zdravnika ali drugo zdravstveno osebje o sočasni uporabi zdravila Cyanokit in drugih zdravil so na koncu tega navodila (glejte »Navodila za ravnanje«).
English: • irregular heart beat
Slovenian: • neredno bitje srca
English: The presence and extent of cyanide poisoning are often initially unknown.
Slovenian: Zastrupitev s cianidom je pogosto sprva neopažena, njena stopnja pa neznana.
English: • freezing/defrosting cycles (15 days submitted to temperatures ranging from -20 to 40°C).
Slovenian: • cikli zamrzovanja/odmrzovanja (15 dni izpostavljenosti temperaturam od -20 °C do 40 °C)
English: Preparation of Cyanokit
Slovenian: Priprava zdravila Cyanokit
English: Detailed instructions for your doctor or other health care professional on how to prepare the Cyanokit infusion and how to determine the dose can be found at the end of this package leaflet (see 'Handling instructions').
Slovenian: Podrobne informacije za zdravnika ali drugo zdravstveno osebje o pripravi infuzije zdravila Cyanokit in določanju odmerka so na koncu tega navodila (glejte »Navodila za ravnanje«).
English: Other medicines and Cyanokit
Slovenian: Druga zdravila in zdravilo Cyanokit
English: Hydroxocobalamin reduced whole blood cyanide concentrations from about 120 nmol/mL to 30-40 nmol/mL by the end of the infusion compared with 70 nmol/mL in dogs receiving sodium chloride 9 mg/mL alone.
Slovenian: Hidroksokobalamin je ob koncu infundiranja zmanjšal celotno koncentracijo cianida v krvi s približno 120 nmol/ml na 30-40 nmol/ml, pri psih, ki so prejemali samo 9 mg/ml natrijevega klorida, pa je koncentracijo zmanjšal na 70 nmol/ml.
English: Following intravenous administration of Cyanokit, significant binding to plasma proteins and low molecular weight physiological compounds occurs, to form various cobalamin-(III) complexes by replacing the hydroxo ligand.
Slovenian: Po intravenski uporabi zdravila Cyanokit pride do pomembne vezave na beljakovine v plazmi in pojava fizioloških spojin z majhno molsko maso, ki s substitucijo hidrokso liganda tvorijo različne komplekse kobalamina-(III).
English: Survival of cyanide-poisoned dogs
Slovenian: Preživetje psov, zastrupljenih s cianidom
English: Swelling, irritation, redness.
Slovenian: Otekanje, iritacija, rdečica.
English: • Chromaturia: all patients will show a dark red colouration of the urine quite marked during the first three days following administration.
Slovenian: • Kromaturija: pri vseh bolnikih se bo v prvih treh dneh po uporabi pojavilo znatno temno rdeče obarvanje urina.
English: Read the leaflet for storage conditions in ambulatory use
Slovenian: Za pogoje shranjevanja pri ambulantni uporabi glejte navodilo za uporabo.
English: If the decision is made to administer another cyanide antidote with Cyanokit, these medicinal products must not be administered concurrently in the same intravenous line (see section 6.2).
Slovenian: Pri odločitvi za uporabo drugega antidota proti cianidu skupaj z zdravilom Cyanokit, se ta zdravila ne smejo dajati sočasno po isti intravenski liniji (glejte poglavje 6.2).
English: If the decision is made to administer another cyanide antidote with Cyanokit, these medicinal products must not be administered concurrently in the same intravenous line.
Slovenian: Pri odločitvi za uporabo drugega antidota proti cianidu skupaj z zdravilom Cyanokit, se ta zdravila ne smejo dajati sočasno po isti intravenski liniji.
English: Observed in vitro interferences of hydroxocobalamin with laboratory tests
Slovenian: Opažene motnje hidroksokobalamina pri laboratorijskih preiskavah in vitro
English: Pleural effusion, dyspnoea, throat tightness, dry throat, chest discomfort.
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora Plevralni izliv, dispneja, stiskanje v grlu, suho grlo, neprijeten občutek v prsnem košu.
English: Artificially increased*
Slovenian: Motnja ni opažena Umetno zvišan*
English: Chemical incompatibility was observed with the mixture of hydroxocobalamin reconstituted solution and the following medicinal products: epinephrine, lidocaine hydrochloride, adenosine, atropine, midazolam, ketamin, succinylcholine chloride, amiodarone hydrochloride, sodium bicarbonate, sodium thiosulfate, sodium nitrite, and has been reported with ascorbic acid.
Slovenian: Kemijsko inkompatibilnost so opazili pri mešanju rekonstituirane raztopine hidroksokobalamina in naslednjih zdravil: epinefrin, lidokainijev klorid, adenozin, atropin, midazolam, ketamin, sukcinilholinijev klorid, amiodaronijev klorid, natrijev hidrogenkarbonat, natrijev tiosulfat, natrijev nitrit, o njej pa so poročali pri askorbinski kislini.
English: Renal and urinary problems
Slovenian: Težave z ledvicami in urinom
English: Coagulation
Slovenian: Koagulacija
English: • usual transport (15 days submitted to temperatures ranging from 5 to 40°C)
Slovenian: • običajni prevoz (15 dni izpostavljenosti temperaturam od 5 °C do 40 °C),
English: What Cyanokit looks like and contents of the pack
Slovenian: Izgled zdravila Cyanokit in vsebina pakiranja
English: Abdominal discomfort, dyspepsia, diarrhoea, vomiting, nausea, dysphagia.
Slovenian: Neprijeten občutek v trebuhu, dispepsija, diareja, bruhanje, navzea, disfagija.
English: No special hazard for humans was identified based on conventional studies of single and repeated dose toxicity and genotoxicity.
Slovenian: Običajne študije toksičnosti pri enkratnih in ponavljajočih se odmerkih in genotoksičnosti ne kažejo posebnega tveganja za človeka.
English: Headache; injection site reaction; peripheral oedema.
Slovenian: Splošne težave in spremembe na mestu aplikacije Glavobol; reakcije na mestu injiciranja; periferni edem.
English: Mean corpuscular volume (MCV) Leucocytes
Slovenian: Povprečni volumen eritrocitov (MCV) Levkociti
English: If these temporary conditions have been exceeded, the product should be discarded.
Slovenian: Zdravilo je treba pri prekoračitvi teh začasnih pogojev zavreči.
English: Cyanokit powder for solution for infusion is a dark red crystalline powder supplied in a glass vial closed with bromobutyl rubber stopper and an aluminium cap with a plastic lid.
Slovenian: Zdravilo Cyanokit prašek za raztopino za infundiranje je temno rdeč kristaliničen prašek, ki je na voljo v stekleni viali, zaprti z zamaškom iz bromobutilne gume in aluminijasto zaporko s plastičnim pokrovom.
English: Cyanokit is an antidote for the treatment of known or suspected cyanide poisoning in all age ranges.
Slovenian: Zdravilo Cyanokit je protistrup za zdravljenje znane zastrupitve s cianidom ali v primeru suma zastrupitve s cianidom za vse starostne skupine.
English: Reversible red colouration of the skin and mucous membranes: most patients will experience it up to 15 days after administration of Cyanokit.
Slovenian: Reverzibilno rdeče obarvanje kože in sluznic: pri večini bolnikov se pojavi v do 15 dneh po dajanju zdravila Cyanokit.
English: * ≥ 10% interference observed on at least one analyser ** Artificially decreased using the diazo method *** Inconsistent results
Slovenian: * ≥ 10 % motnje, opažene pri vsaj enem analizatorju.
English: Prothrombin time (PT) Quick or INR
Slovenian: Quickov test ali INR
English: Decrease in the percentage of lymphocytes.
Slovenian: Bolezni krvi in limfatičnega sistema Zmanjšanje odstotka limfocitov.
English: One intravenous infusion set.
Slovenian: En komplet za intravensko infundiranje.
English: Monocytes
Slovenian: Monociti
English: Survival at hour 4 and at day 14 was significantly greater in 75 mg/kg and 150 mg/kg hydroxocobalamin dose groups compared with dogs receiving sodium chloride 9 mg/mL alone:
Slovenian: Preživetje po 4 urah in po 14 dnevu je bilo pri skupinah, ki so prejemale odmerke 75 mg/kg hidroksokobalamina in 150 mg/kg hidroksokobalamina, pomembno večje kot pri psih, ki so prejemali samo 9 mg/ml natrijevega klorida:
English: All patients will show a dark red colouration of the urine quite marked during the first three days following administration.
Slovenian: Pri vseh bolnikih se bo v prvih treh dneh po uporabi pojavilo znatno temno rdeče obarvanje urina.
English: Effects on blood cyanide assay
Slovenian: Učinki na preizkus cianida v krvi
English: The incidence of brain lesions was markedly lower in dogs having received 150 mg/kg hydroxocobalamin than in dogs having received 75 mg/kg hydroxocobalamin or sodium chloride 9 mg/mL.
Slovenian: Pogostnost možganskih lezij je bila pri psih, ki so prejemali 150 mg/kg hidroksokobalamina, znatno manjša kot pri psih, ki so prejemali 75 mg/kg hidroksokobalamina ali 9 mg/ml natrijevega klorida.
English: Oxalate crystals have been observed in the urine of healthy volunteers given hydroxocobalamin.
Slovenian: V urinu zdravih prostovoljcev, ki so dobili hidroksokobalamin, so opazili oksalatne kristale.
English: • Cyanide-poisoned patients
Slovenian: • Bolniki, zastrupljeni s cianidom
English: Because of its deep red colour, hydroxocobalamin has the potential to induce a red colouration of the skin and therefore may interfere with burn assessment.
Slovenian: Hidroksokobalamin je temno rdeč, zato lahko povzroči rdeče obarvanje kože in moti ocenjevanje stopnje opeklin.
English: Dogs were poisoned by intravenous administration of a lethal dose of potassium cyanide.
Slovenian: Zastrupili so jih z intravenskim odmerjanjem smrtnega odmerka kalijevega cianida.
English: Cyanide poisoning may result from exposure to smoke from closed space fires, inhalation, ingestion, or dermal exposure.
Slovenian: Zastrupitev s cianidom je lahko posledica izpostavljenosti dimu pri požaru v zaprtem prostoru, vdihavanja, zaužitja ali izpostavljenosti prek kože.
English: Cyanokit has been administered to this patient.
Slovenian: Ta bolnik je prejel zdravilo Cyanokit.
English: • fluid in the chest (pleural effusion)
Slovenian: • tekočina v prsnem košu (plevralni izliv)
English: Initial dose Adults: The initial dose of Cyanokit is 5 g (2 x 100 mL).
Slovenian: Začetni odmerek Odrasli: Začetni odmerek zdravila Cyanokit je 5 g (2 x 100 ml).
English: The predominant mean half-life of free and total cobalamins-(III) was approximately 26 to 31 hours at the 5 and 10 g dose level.
Slovenian: Pri odmerkih 5 in 10 g je bil prevladujoč povprečni razpolovni čas prostih in skupnih kobalaminov(III) približno 26 do 31 ur.
English: Administration of hydroxocobalamin was generally associated with a normalisation of blood pressure (systolic blood pressure > 90 mmHg) in 17 of 21 patients (81%) who had low blood pressure (systolic blood pressure > 0 and ≤ 90 mmHg) after exposure to cyanide.
Slovenian: Pri 17 od 21 bolnikov (81%), ki so imeli po izpostavljenosti cianidu nizek krvni tlak (sistolični krvni tlak > 0 in ≤ 90 mmHg), je bila na splošno uporaba hidroksokobalamina povezana z normalizacijo krvnega tlaka (sistolični krvni tlak > 90 mmHg).
English: Chemical and physical in-use stability of the reconstituted solution with sodium chloride 9 mg/mL (0.9%) has been demonstrated for 6 hours at a temperature between 2°C and 40°C.
Slovenian: Raztopina, rekonstituirana z raztopino natrijevega klorida 9 mg/ml (0,9 %) ostane kemično in fizikalno stabilna 6 ur pri temperaturi od 2 °C do 40 °C.
English: After reconstitution with 200 mL of diluent, each mL of the reconstituted solution contains 25 mg of hydroxocobalamin.
Slovenian: Po rekonstituciji z 200 ml topila vsebuje en ml rekonstituirane raztopine 25 mg hidroksokobalamina.
English: Memory impairment; dizziness.
Slovenian: Bolezni živčevja Motnje spomina; omotica.
English: • symptoms such as headache or dizziness, as they may be due to a rise in blood pressure.
Slovenian: • simptomi, kot so glavobol ali omotica, ker so lahko posledica zvišanja krvnega tlaka; zvišanje krvnega tlaka se pojavlja zlasti ob koncu zdravljenja, krvni tlak pa se navadno vrne na izhodiščno vrednost v nekaj urah
English: Dogs then received sodium chloride 9 mg/mL, 75 mg/kg or 150 mg/kg hydroxocobalamin, administered intravenously over 7.5 minutes.
Slovenian: Nato so jim v 7,5 minutah intravensko dali 9 mg/ml natrijevega klorida, 75 mg/kg hidroksokobalamina ali 150 mg/kg hidroksokobalamina.
English: The low molecular weight cobalamins-(III) formed including hydroxocobalamin are termed free cobalamins-(III); the sum of free and protein-bound cobalamins is termed total cobalamins-(III).
Slovenian: Nastali kobalamini-(III) z majhno molsko maso, vključno s hidroksokobalaminom, se imenujejo prosti kobalamini-(III).
English: Transient, generally asymptomatic, increase in blood pressure may occur in patients receiving hydroxocobalamin.
Slovenian: Pri bolnikih, ki prejemajo hidroksokobalamin, lahko pride do prehodnega, na splošno asimptomatičnega zvišanja krvnega tlaka.
English: After reconstitution with 100 mL of diluent, each mL of the reconstituted solution contains 25 mg of hydroxocobalamin.
Slovenian: Po rekonstituciji s 100 ml topila vsebuje en ml rekonstituirane raztopine 25 mg hidroksokobalamina.
English: Calcium
Slovenian: Kalcij
English: What Cyanokit contains
Slovenian: Kaj vsebuje zdravilo Cyanokit
English: The rapid and complete recovery of haemodynamics and subsequently of blood gases, pH, and lactate after cyanide poisoning likely contributed to the better outcome of the hydroxocobalamin-treated animals.
Slovenian: Pri živalih, ki so prejemale hidroksokobalamin, je po zastrupitvi s cianidom k boljšem izidu verjetno prispevalo hitro in popolno izboljšanje hemodinamike, s tem pa tudi vrednosti plinov v krvi, pH in laktata.
English: Adults: The subsequent dose of Cyanokit is 5 g (2 x 100 mL).
Slovenian: Odrasli: Naslednji odmerek zdravila Cyanokit je 5 g (2 x 100 ml).
English: Type II colourless 250 mL glass vial closed with bromobutyl rubber stopper and an aluminium cap with a plastic lid.
Slovenian: 250-mililitrska viala iz brezbarvnega stekla vrste II, zaprta z zamaškom iz bromobutilne gume in aluminijasto zaporko s plastičnim pokrovčkom.
English: • redness of the face (flush).
Slovenian: • rdečica obraza (vročinski obliv)
English: Excipient: Hydrochloric acid (for pH adjustment).
Slovenian: Pomožna snov: klorovodikova kislina (za uravnavanje pH).
English: The vial contains 5 g of hydroxocobalamin.
Slovenian: Ena viala vsebuje 5 g hidroksokobalamina.
English: Paediatric population: In infants to adolescents (0 to 18 years old), the maximum total recommended dose is 140 mg/kg not exceeding 10 g.
Slovenian: Pediatrična populacija: Od dojenčkov do mladostnikov (0 do 18 let starosti) je največji skupni priporočeni odmerek 140 mg/kg, vendar ne sme preseči 10 g.
English: Only when sodium chloride 9 mg/mL (0.9%) solution for injection is not available, Lactated Ringer solution or glucose 50 mg/mL (5%) solution for injection can also be used.
Slovenian: Če natrijev klorid 9 mg/ml (0,9 %) raztopina za injiciranje ni na voljo, se lahko uporabi raztopina Ringerjevega laktata ali glukoza 50 mg/ml (5 %) raztopina za injiciranje.
English: Cyanokit contains the active substance hydroxocobalamin.
Slovenian: Zdravilo Cyanokit vsebuje zdravilno učinkovino hidroksokobalamin.
English: How Cyanokit is used
Slovenian: Kako uporabljati zdravilo Cyanokit
English: Gamma glutamyl transferase (GGT)
Slovenian: Gamaglutamiltransferaza (GGT)
English: Adults: The subsequent dose of Cyanokit is 5 g (200 mL, complete volume of reconstituted solution).
Slovenian: Odrasli: Naslednji odmerek zdravila Cyanokit je 5 g (200 ml, celotna prostornina rekonstituirane raztopine).
English: Powder for solution for infusion containing 2.5 g of hydroxocobalamin.
Slovenian: Prašek za raztopino za infundiranje, ki vsebuje 2,5 g hidroksokobalamina.
English: Powder for solution for infusion containing 5 g of hydroxocobalamin.
Slovenian: Prašek za raztopino za infundiranje, ki vsebuje 5 g hidroksokobalamina.
English: Approximately 50 known or suspected cyanide victims aged 65 or older received hydroxocobalamin in clinical studies.
Slovenian: V kliničnih študijah je hidroksokobalamin prejelo približno 50 bolnikov, starejših od 65 let, z znano zastrupitvijo s cianidom ali sumom nanjo.
English: Treatment of known or suspected cyanide poisoning in all age ranges.
Slovenian: Zdravljenje znane zastrupitve s cianidom ali v primeru suma zastrupitve s cianidom za vse starostne skupine.
English: A total of 245 patients with suspected or known cyanide-poisoning were included in the clinical studies of the efficacy of hydroxocobalamin as an antidote.
Slovenian: V kliničnih študijah učinkovitosti hidroksokobalamina kot antidota je sodelovalo skupaj 245 bolnikov z znano zastrupitvijo s cianidom ali sumom nanjo.
English: Cyanokit must not be mixed with diluents other than sodium chloride 9 mg/mL (0.9%) solution for injection or Lactated Ringer solution or glucose 50 mg/mL (5%) solution for injection.
Slovenian: Sočasna uporaba zdravila Cyanokit in drugih zdravil Zdravilo Cyanokit se ne sme mešati z drugimi topili, razen z natrijevim kloridom 9 mg/ml (0,9 %) raztopino za injiciranje, raztopino Ringerjevega laktata ali glukozo 50 mg/ml (5 %) raztopino za injiciranje.
English: Similarly, mean free and total cobalamins-(III) Cmax values of 197 and 995 µg eq/mL, respectively, were determined following the dose of 10 g Cyanokit.
Slovenian: Podobno je bila po 10-gramskem odmerku zdravila Cyanokit povprečna vrednost Cmax prostih kobalaminov-(III) 197, skupnih kobalaminov-(III) pa 995 µg eq/ml.
English: Type I colourless 250 mL glass vial closed with bromobutyl rubber stopper and an aluminium cap with a plastic lid.
Slovenian: 250-mililitrska viala iz brezbarvnega stekla vrste I, zaprta z zamaškom iz bromobutilne gume in aluminijasto zaporko s plastičnim pokrovčkom.
English: Artificially decreased*
Slovenian: ** Umetno znižan z diazo metodo.
English: Sodium chloride 9 mg/mL (0.9%) solution for injection is the recommended diluent.
Slovenian: Priporočeno topilo je natrijev klorid 9 mg/ml (0,9 %) raztopina za injiciranje.
English: Each vial contains 2.5 g of hydroxocobalamin.
Slovenian: Ena viala vsebuje 2,5 g hidroksokobalamina.
English: Duration of interference after a 5 g dose
Slovenian: Umetno znižan* Nepredvidljiv*** Trajanje motnje po 5-gramskem odmerku
English: Developmental toxicity, including teratogenicity, was observed in rats and rabbits at dose levels of 150 mg/kg and higher administered daily throughout organogenesis.
Slovenian: Pri podganah in kuncih so pri odmerkih 150 mg/kg in več, danih dnevno ves čas trajanja organogeneze, opazili toksičnost za razvoj, vključno s teratogenostjo.