FrancophonIA/ELRC3.0 huggingface dataset:
English: For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder
Slovenian: Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom:
English: The clinical relevance of this interaction for single dose administration of ulipristal acetate as emergency contraception is not known.
Slovenian: Klinični pomen tega medsebojnega delovanja pri uporabi enega odmerka ulipristalacetata kot nujne kontracepcije ni znan.
English: This medicine is a contraceptive used to prevent a pregnancy from starting.
Slovenian: To zdravilo je kontracepcijsko sredstvo, ki se uporablja za preprečitev nastopa nosečnosti.
English: For women who have used enzyme-inducing drugs in the past 4 weeks, ellaOne is not recommended (see section 4.4) and non-hormonal emergency contraception (i.e. a copper intrauterine device (Cu-IUD)) should be considered.
Slovenian: Pri ženskah, ki so v zadnjih 4 tednih uporabljale zdravila, ki inducirajo encime, uporaba zdravila ellaOne ni priporočljiva (glejte poglavje 4.4), hkrati pa je treba razmisliti o nehormonski nujni kontracepciji (tj. bakrenem materničnem vložku (Cu-IUD)).
English: This medicine does not require any special storage conditions.
Slovenian: Za to zdravilo ne veljajo posebni pogoji shranjevanja.
English: If you have been told by your doctor or other healthcare professional that you have an intolerance to some sugars, tell your pharmacist before taking this medicine.
Slovenian: Če vam je zdravnik ali drug zdravstveni delavec povedal, da ne prenašate nekaterih sladkorjev, se pred uporabo tega zdravila posvetujte s farmacevtom.
English: Akacia Group, s.r.o.
Slovenian: Česká republika Akacia Group, s.r.o.
English: No dose adjustment is necessary.
Slovenian: Odmerka ni treba prilagoditi.
English: This medicine will not protect you against HIV infection or any other sexually transmitted diseases (e.g. chlamydia, genital herpes, genital warts, gonorrhoea, hepatitis B and syphilis).
Slovenian: To zdravilo vas ne bo zaščitilo pred okužbo z virusom HIV ali drugimi spolno prenosljivimi boleznimi (kot so klamidija, genitalni herpes, genitalne bradavice, gonoreja, hepatitis B in sifilis).
English: Therefore, if a woman wishes to start or continue using hormonal contraception, she can do so after using ellaOne, however, she should be advised to use a reliable barrier method until the next menstrual period.
Slovenian: Torej, če želi ženska začeti ali nadaljevati uporabo hormonske kontracepcije, to lahko stori po uporabi zdravila ellaOne, vendar ji je treba svetovati, naj do naslednje menstruacije uporablja zanesljivo pregradno metodo.
English: Contents of the pack and other information What ellaOne contains
Slovenian: Vsebina pakiranja in dodatne informacije Kaj vsebuje zdravilo ellaOne
English: Take the tablet without delay.
Slovenian: Ne odlašajte z zaužitjem tablete.
English: In an open-label clinical trial, which enrolled women who presented for emergency contraception and were treated with ulipristal acetate between 48 and 120 hours after unprotected intercourse, a pregnancy rate of 2.1% (26/1241) was observed.
Slovenian: V odprtem kliničnem preskušanju, v katerem so sodelovale ženske, ki so potrebovale nujno kontracepcijo ter so prejele ulipristalacetat v času od 48 do 120 ur po nezaščitenem spolnem odnosu ali neučinkoviti kontracepciji, je bil odstotek nosečnosti 2,1 % (26/1241).
English: Pregnancy ellaOne is not intended for use during pregnancy and should not be taken by any woman suspected or known to be pregnant (see section 4.2).
Slovenian: Zdravilo ellaOne ni namenjeno uporabi med nosečnostjo in ga ne sme vzeti nobena ženska, ki sumi ali ve, da je noseča (glejte poglavje 4.3).
English: You should take the tablet as soon as possible after sex, and within a maximum of 5 days (120 hours).
Slovenian: Tableto morate vzeti čim prej po spolnem odnosu in najpozneje po 5 dneh (120 urah).
English: Unprotected sex at any time during your cycle can lead to pregnancy.
Slovenian: Nezaščiten spolni odnos kadar koli med menstrualnim ciklusom lahko privede do nosečnosti.
English: Ulipristal acetate is an emergency contraceptive that decreases pregnancy risk after unprotected intercourse but does not confer contraceptive protection for subsequent acts of intercourse.
Slovenian: Ulipristalacetat je nujno kontracepcijsko sredstvo, ki zmanjšuje tveganje za nosečnost po nezaščitenem spolnem odnosu, vendar ne zagotavlja kontracepcijske zaščite za nadaljnje spolne odnose.
English: No pharmacokinetic studies with ulipristal acetate have been performed in females with impaired renal or hepatic function.
Slovenian: Farmakokinetičnih študij z ulipristalacetatom pri ženskah z oslabljeno ledvično ali jetrno funkcijo niso izvedli.
English: ellaOne is not to be used for regular contraception
Slovenian: Zdravilo ellaOne se ne sme uporabljati kot redna kontracepcijska metoda.
English: Ulipristal acetate is highly bound (>98%) to plasma proteins, including albumin, alpha-l-acid glycoprotein, and high density lipoprotein.
Slovenian: Ulipristalacetat se močno veže (> 98 %) na plazemske beljakovine, vključno z albumini, alfa-1glikoproteini in lipoproteini visoke gostote.
English: Limited and inconclusive data suggest that there may be reduced efficacy of ellaOne with increasing body weight or body mass index (BMI) (see section 5.1).
Slovenian: Omejeni in nedokončni podatki kažejo, da se lahko učinkovitost zdravila ellaOne manjša z večanjem telesne mase ali indeksa telesne mase (ITM) (glejte poglavje 5.1).
English: Ulipristal acetate is not intended for use during pregnancy and should not be taken by any woman suspected or known to be pregnant.
Slovenian: Ulipristalacetat ni namenjen za uporabo med nosečnostjo in ga ne sme vzeti nobena ženska, ki sumi ali ve, da je noseča.
English: In all women, emergency contraception should be taken as soon as possible after unprotected intercourse, regardless of the woman's body weight or BMI.
Slovenian: Pri vseh ženskah je treba nujno kontracepcijo vzeti čim prej po nezaščitenem spolnem odnosu, ne glede na telesno maso ali ITM ženske.
English: Limited and inconclusive data from clinical trials suggest a possible trend for a reduced contraceptive efficacy of ulipristal acetate with high body weight or BMI (see section 4.4).
Slovenian: Omejeni in nedokončni podatki iz kliničnih preskušanj kažejo morebiten trend za zmanjšano učinkovitost kontracepcije ulipristalacetata pri veliki telesni masi ali ITM (glejte poglavje 4.4).
English: There were no safety differences in these subjects in terms of incidence and severity of adverse reactions, change in duration or volume of menses or incidence of intermenstrual bleeding.
Slovenian: Med temi ženskami niso bile opažene razlike v varnosti zdravila glede incidence in resnosti neželenih reakcij, sprememb v trajanju menstruacije ali količini menstrualne krvi ali glede incidence krvavitev v času med dvema menstruacijama.
English: The CYP3A4 inhibitor ritonavir can also have an inducing effect on CYP3A4 when ritonavir is used for a longer period.
Slovenian: Zaviralec CYP3A4, ritonavir, ima lahko prav tako inducirajoče učinke na CYP3A4, če je njegova uporaba dolgotrajna.
English: Laboratorios León Farma S.A. C/ La Vallina, s/n Pol. Ind. Navatejera 24008 Navatejera, León Spain
Slovenian: C/ La Vallina, s/n Pol. Ind. Navatejera 24008 Navatejera, León
English: In all women, emergency contraception should be taken as soon as possible after unprotected intercourse.
Slovenian: Pri vseh ženskah je treba nujno kontracepcijo uporabiti čim prej po nezaščitenem spolnem odnosu.
English: Take one tablet as soon as possible after unprotected sex or contraceptive failure.
Slovenian: Vzemite eno tableto čim prej po nezaščitenem spolnem odnosu ali neučinkoviti kontracepciji.
English: Emergency contraception
Slovenian: Nujna kontracepcija
English: In 18.5% of the women a delay of more than 7 days occurred, and in 4% the delay was greater than 20 days.
Slovenian: Pri približno 18,5% žensk je menstruacijski ciklus zamujal več kot 7 dni, pri 4 % žensk pa je bila zamuda daljša od 20 dni.
English: Women should be advised to use a reliable barrier method for all subsequent acts of intercourse until the next menstrual period.
Slovenian: Ženskam je treba svetovati, naj do naslednje menstruacije uporabljajo zanesljivo pregradno metodo za vse nadaljnje spolne odnose.
English: This medicine may make regular hormonal contraceptives, like pills and patches, temporarily less effective.
Slovenian: Druga kontracepcijska sredstva in zdravilo ellaOne Zaradi tega zdravila je lahko redna hormonska kontracepcija, kot so tablete in obliži, začasno manj učinkovita.
English: Women who become pregnant after taking ulipristal acetate should contact their doctor (see section 4.6).
Slovenian: Ženske, ki zanosijo po jemanju ulipristalacetata, se morajo posvetovati z zdravnikom (glejte poglavje 4.6).
English: Before taking this medicine, if your period is late, tell your pharmacist, doctor or other healthcare professional, or do a pregnancy test in order to make sure you are not already pregnant (see section “Warning and precautions”).
Slovenian: Pred jemanjem tega zdravila ali če vam menstruacija zamuja, o tem obvestite farmacevta, zdravnika ali drugega zdravstvenega delavca ali pa opravite test nosečnosti, da se prepričate, da niste že noseči (glejte poglavje »Opozorila in previdnostni ukrepi«).
English: The meta-analysis of the four clinical studies conducted with ulipristral acetate presented below excluded women who had further acts of unprotected intercourse.
Slovenian: Pri spodaj predstavljeni metaanalizi štirih kliničnih študij z ulipristilacetatom so izključili ženske, ki so nadaljevale z nezaščitenimi spolnimi odnosi.
English: 17, rue de Pontoise 95520 Osny France
Slovenian: 17, rue de Pontoise F-95520 Osny
English: Pharmacodynamic data show that even when taken immediately before ovulation is scheduled to occur (when LH has already started to rise), ulipristal acetate is able to postpone follicular rupture for at least 5 days in 78.6% of cases (p<0.005 vs. levonorgestrel and vs. placebo)
Slovenian: Farmakodinamični podatki kažejo, da je ulipristalacetat, tudi če se vzame tik pred predvideno ovulacijo (ko je raven LH že začela naraščati), v 78,6 % primerov zmožen odložiti razpok folikla za vsaj 5 dni (p < 0,005 v primerjavi z levonorgestrelom in placebom) (glejte preglednico).
English: The terminal half-life of ulipristal acetate in plasma following a single 30 mg dose is estimated to 32.4 ± 6.3 hours, with a mean oral clearance (CL/F) of 76.8 ± 64.0 L/h.
Slovenian: Končni razpolovni čas ulipristalacetata v plazmi po enkratnem 30-miligramskem odmerku je ocenjen na 32,4 ± 6,3 ure, s povprečnim peroralnim očistkom (CL/F) 76,8 ± 64,0 l/h.
English: Visual disturbance Abnormal sensation in eye Ocular hyperaemia
Slovenian: Očesne bolezni motnje vida nenormalen občutek v očesu očesna hiperemija fotofobija
English: In vitro data indicate that this is predominantly mediated by CYP3A4, and to a small extent by CYP1A2 and CYP2A6.
Slovenian: Podatki študij in vitro kažejo, da pri tem večinoma sodeluje CYP3A4, manj pa CYP1A2 in CYP2A6CYP2A6.
English: Contents of the pack and other information - Useful information about contraception
Slovenian: Shranjevanje zdravila ellaOne Vsebina pakiranja in dodatne informacije - Uporabne informacije o kontracepciji
English: See leaflet for further information.
Slovenian: Za več informacij glejte priloženo navodilo.
English: After intake of ulipristal acetate for emergency contraception, breast-feeding is not recommended for one week.
Slovenian: Po vnosu ulipristalacetata za nujno kontracepcijo se dojenje odsvetuje en teden.
English: Results in vivo with the P-gp substrate fexofenadine were inconclusive.
Slovenian: Rezultati in vivo s substratom P-gp, feksofenadinom, niso bili dokončni.
English: Do not take ellaOne together with another emergency contraceptive pill that contains levonorgestrel.
Slovenian: Zdravila ellaOne ne jemljite skupaj z drugimi nujnimi kontracepcijskimi tabletami, ki vsebujejo levonorgestrel.
English: Golden film-coated tablet of shield shape (around 10,8 mm diameter) with “ella” engraved on both sides.
Slovenian: Filmsko obložena tableta zlate barve v obliki ščita (približnega premera 10,8 mm) z vtisnjenim napisom “ella” na obeh straneh.
English: Pregnancy rate (%) within 72h of unprotected intercourse or contraceptive failure2
Slovenian: Razmerje nosečnosti (%) v roku 72 ur po nezaščitenem spolnem odnosu ali neučinkoviti kontracepciji2
English: When your period is late or when you have symptoms of pregnancy (heavy breasts, morning sickness) you should consult a doctor or other healthcare professional before taking the tablet.
Slovenian: Če vam menstruacija zamuja ali če imate simptome nosečnosti (težke prsi, jutranja slabost), se pred jemanjem tablete posvetujte z zdravnikom ali drugim zdravstvenim delavcem.
English: See section “Pregnancy, breast-feeding and fertility” for more information.
Slovenian: Za več informacij glejte poglavje »Nosečnost, dojenje in plodnost«.
English: - CYP3A4 inhibitors
Slovenian: − Zaviralci CYP3A4
English: Ulipristal acetate is an orally-active synthetic selective progesterone receptor modulator which acts via high-affinity binding to the human progesterone receptor.
Slovenian: Ulipristalacetat je peroralno aktivni selektivni sintetični modulator progesteronskih receptorjev, ki se v človeškem organizmu z visoko afiniteto veže na progesteronske receptorje.
English: - if you are allergic to ulipristal acetate or any of the other ingredients of this medicine (listed in section 6).
Slovenian: Ne jemljite zdravila ellaOne - če ste alergični na ulipristalacetat ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Do not take this medicine together with another emergency contraceptive pill that contains levonorgestrel.
Slovenian: Tega zdravila ne jemljite skupaj z drugimi nujnimi kontracepcijskimi tabletami, ki vsebujejo levonorgestrel.
English: If a woman's menstrual period is late or in case of symptoms of pregnancy, pregnancy should be excluded before the tablet is administered.
Slovenian: Če ženski zamuja menstruacija ali se pojavijo znaki nosečnosti, je treba izključiti nosečnost, preden ženska vzame tableto.
English: No data are available on the efficacy of ulipristal acetate when taken more than 120 hours (5 days) after unprotected intercourse.
Slovenian: Na voljo ni podatkov o učinkovitosti ulipristalacetata pri ženskah, ki so ga zaužile več kot 120 ur (5 dni) po nezaščitenem spolnem odnosu.
English: Ulipristal acetate for emergency contraception is suitable for any woman of child bearing age, including adolescents.
Slovenian: Ulipristal acetat za nujno kontracepcijo je primeren za vsako žensko v rodni dobi, vključno z mladostnicami.
English: ellaOne is available in a carton containing one blister of 1 film-coated tablet.
Slovenian: Zdravilo ellaOne je na voljo v škatli, ki vsebuje en pretisni omot z 1 filmsko obloženo tableto.
English: However, if your period is more than 7 days late; if it is unusually light or unusually heavy; or if you experience symptoms such as abdominal (stomach) pain, breast tenderness, vomiting or nausea, you may be pregnant.
Slovenian: Vendar če zamuja za več kot 7 dni, če je nenavadno šibka ali močna ali če opazite simptome, kot so bolečine v trebuhu, občutljive dojke, bruhanje ali slabost s siljenjem na bruhanje, ste morda noseči.
English: The most commonly reported adverse reactions were headache, nausea, abdominal pain and dysmenorrhea.
Slovenian: Najpogostejši neželeni učinki, o katerih so poročali, so bili glavobol, navzea, bolečina v trebuhu in dismenoreja.
English: If you take this medicine while you are breast-feeding a baby, do not breast-feed for one week after taking this medicine.
Slovenian: Če vzamete to zdravilo v obdobju dojenja, otroka en teden po tem ne dojite.
English: In vivo results show that the administration of ulipristal acetate with a strong CYP3A4 inducer such as rifampicin markedly decreases Cmax and AUC of ulipristal acetate by 90% or more and decreases ulipristal acetate half-life by 2.2-fold corresponding to an approximately 10-fold decrease of ulipristal acetate exposure.
Slovenian: Rezultati in vivo so pokazali, da uporaba ulipristalacetata z močnim induktorjem CYP3A4, kot je rifampicin, znatno zmanjša vrednosti Cmax in AUC ulipristalacetata za 90 % ali več ter skrajša razpolovni čas ulipristalacetata za 2,2-krat, kar je enako približno 10-krat manjši izpostavljenosti ulipristalacetatu.
English: Ulipristal acetate is excreted in breast milk (see section 5.2).
Slovenian: Ulipristalacetat se izloča v materino mleko (glejte poglavje 5.2).
English: In addition, the second comparative trial described above also provides data on 100 women treated with ulipristal acetate from 72 to 120 hours after unprotected intercourse, in whom no pregnancies were observed.
Slovenian: V drugem komparativnem preskušanju, ki je opisano zgoraj in vključuje 100 žensk, ki so prejele ulipristalacetat od 72 do 120 ur po nezaščitenem spolnem odnosu, niso opazili nobene nosečnosti.
English: Two trials provide efficacy data on ellaOne used up to 120 hours after unprotected intercourse.
Slovenian: Podatki učinkovitosti dveh kliničnih preskušanj zdravila ellaOne prikazujejo učinkovitost do 120 ur po nezaščitenem spolnem odnosu.
English: Diarrhoea Dry mouth Dyspepsia Flatulence
Slovenian: driska suha usta dispepsija flatulenca
English: - The other ingredients are lactose monohydrate, povidone, croscarmellose sodium, magnesium stearate.
Slovenian: - Druge sestavine zdravila so laktoza monohidrat, povidon, premreženi natrijev karmelozat in magnezijev stearat.
English: N pregnancies 0
Slovenian: Št. nosečnosti
English: Medicinal product not subject to medical prescription.
Slovenian: Izdaja zdravila je brez recepta.
English: If you wish to start or continue with a regular method of contraception after using this medicine, you can do so but you should also use condoms until your next period.
Slovenian: Če želite po uporabi tega zdravila začeti ali nadaljevati z redno kontracepcijsko metodo, lahko to storite, vendar morate tudi v tem primeru do naslednje menstruacije uporabljati kondome.
English: The effects of CYP3A4 inhibitors are unlikely to have any clinical consequences.
Slovenian: Ni verjetno, da bi imeli učinki zaviralcev CYP3A4 kakršne koli klinične posledice.
English: The carton contains one blister.
Slovenian: Škatla vsebuje en pretisni omot.
English: If you have any further questions on the use of this medicine, ask your pharmacist, doctor or other healthcare professional.
Slovenian: Če imate dodatna vprašanja o uporabi tega zdravila, se posvetujte s farmacevtom, zdravnikom ali drugim zdravstvenim delavcem.
English: Medicinal products affecting gastric pH
Slovenian: Zdravila, ki vplivajo na vrednost pH v želodcu
English: ellaOne is available in a carton containing one blister of 1 tablet.
Slovenian: Zdravilo ellaOne je na voljo v škatli, ki vsebuje en pretisni omot z eno tableto.
English: Other medicines and ellaOne
Slovenian: Druga zdravila in zdravilo ellaOne
English: If you vomit after taking ellaOne
Slovenian: Če bruhate po zaužitju zdravila ellaOne
English: Ulipristal acetate n=34
Slovenian: Ulipristalacetat n = 34
English: In vitro data indicate that ulipristal acetate may be an inhibitor of BCRP (Breast Cancer Resistance Protein) transporters at the intestinal level.
Slovenian: Podatki in vitro kažejo, da je lahko ulipristalacetat zaviralec proteina odpornosti pri raku dojke (BCRP- Breast Cancer Resistance Protein) v črevesju.
English: Ulipristal acetate also has high affinity for the glucocorticoid receptor and in vivo, in animals, antiglucocorticoid effects have been observed.
Slovenian: Ulipristalacetat se veže z visoko afiniteto tudi na glukokortikoidne receptorje, v študijah in vivo na živalih pa je bilo opaženo tudi antiglukokortikoidno delovanje.
English: If you experience these symptoms, do not drive or use machines ellaOne contains lactose
Slovenian: Če imate te simptome, ne upravljajte vozil ali strojev.
English: LABORATOIRE HRA PHARMA 200 avenue de Paris
Slovenian: Imetnik dovoljenja za promet z zdravilom LABORATOIRE HRA PHARMA 200 avenue de Paris
English: QR code linking to package leaflet to be included Package leaflet online at
Slovenian: Vključena bo povezava z oznako QR do navodila za uporabo Navodilo za uporabo na spletnem mestu
English: What you need to know before you take ellaOne Do not take ellaOne
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo ellaOne
English: Concomitant use of ulipristal acetate and emergency contraception containing levonorgestrel is not recommended (see section 4.5).
Slovenian: Sočasna uporaba ulipristalacetata z nujno kontracepcijo, ki vsebuje levonorgestrel, se ne priporoča (glejte poglavje 4.5).
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu/.
Slovenian: Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila: http://www.ema.europa.eu.
English: What ellaOne is and what it is used for What you need to know before you take ellaOne How to take ellaOne
Slovenian: Kaj je zdravilo ellaOne in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo ellaOne Kako jemati zdravilo ellaOne Možni neželeni učinki
English: There is no relevant use of ulipristal acetate for children of prepubertal age in the indication emergency contraception.
Slovenian: Pediatrična populacija Pri otrocih pred puberteto ni ustrezne uporabe za ulipristalacetat pri indikaciji nujne kontracepcije.
English: Treatment after LH surge but before LH peak n=10
Slovenian: Jemanje zdravila po zvišanju ravni LH, vendar pred najvišjo ravnjo n = 10
English: Ulipristal acetate is a lipophilic compound and is distributed in breast milk, with a mean daily excretion of 13.35 µg [0-24 hours], 2.16 µg [24-48 hours], 1.06 µg [48-72 hours], 0.58 µg [72-96 hours], and 0.31 µg [96-120 hours].
Slovenian: Izloča se v materino mleko, pri čemer je povprečno dnevno izločanje 13,35 µg [0-24 ur], 2,16 µg [24-48 ur], 1,06 µg [48-72 ur], 0,58 µg [72-96 ur] in 0,31 µg [96120 ur].
English: If you vomit (be sick, throw up) within 3 hours of taking the tablet, take another tablet as soon as possible.
Slovenian: Če bruhate v 3 urah po zaužitju tablete, vzemite še eno tableto takoj, ko bo mogoče.
English: Your doctor may prescribe another type of (non-hormonal) emergency contraceptive, i.e. a copper intrauterine device (Cu-IUD): - medicines used to treat epilepsy (for example, primidone, phenobarbital, phenytoin,
Slovenian: Zdravnik vam lahko predpiše drugo vrsto (nehormonske) nujne kontracepcije, tj. bakreni maternični vložek (CuIUD): - zdravila za zdravljenje epilepsije (npr. primidon, fenobarbital, fenitoin, fosfenitoin, karbamazepin,
English: Following oral administration of a single 30 mg dose, ulipristal acetate is rapidly absorbed, with a peak plasma concentration of 176 ± 89 ng/ml occurring approximately 1 hour (0.5-2.0 h) after ingestion, and with an AUC0-∞ of 556 ± 260 ng.h/ml.
Slovenian: Po enkratnem 30-miligramskem peroralnem odmerku se ulipristalacetat hitro absorbira; najvišja plazemska koncentracija 176 ± 89 ng/ml se pojavi približno 1 uro (0,5-2,0 ure) po zaužitju zdravila, AUC0-∞ pa je 556 ± 260 ng.h/ml.
English: The effects of ulipristal acetate on BCRP are unlikely to have any clinical consequences.
Slovenian: Ni verjetno, da bi imeli učinki ulipristalacetata na BCRP kakršne koli klinične posledice.
English: Administration of ulipristal acetate (10 mg tablet) together with the proton pump inhibitor esomeprazole (20 mg daily for 6 days) resulted in approximately 65% lower mean Cmax, a delayed Tmax (from a median of 0.75 hours to 1.0 hours) and 13% higher mean AUC.
Slovenian: Uporaba ulipristalacetata (10 mg tablete) v kombinaciji z zaviralcem protonske črpalke, esomeprazolom (20 mg na dan 6 dni), je povzročila približno 65 % manjšo povprečno vrednost Cmax, zapozneli Tmax (z mediane 0,75 ure na 1,0 ure) in 13 % večjo povprečno vrednost AUC.