FrancophonIA/ELRC3.0 huggingface dataset:
English: Distribution: The steady state volume of distribution with intravenous administration of a 90 mg dose of enfuvirtide was 5.5 ± 1.1 l. Enfuvirtide is 92% bound to plasma proteins in HIV infected plasma over a plasma concentration range of 2 to 10 µg/ml.
Danish: Fordeling: Steady state-distributionsvolumen efter intravenøs administration af en 90 mg dosis enfuvirtid var 5,5 ± 1,1 l. 92 % af enfuvirtid bindes til plasmaproteiner i hiv-inficeret plasma over en plasmakoncentrationsspændvidde fra 2 til 10 µg/ml.
English: For instructions on reconstitution before administration, see section 6.6.
Danish: For instruktioner om rekonstitution af lægemidlet før administration, se pkt.
English: Check for any places where you may have a reaction by pressing the skin to see if there are any hard bumps.
Danish: Undersøg huden for reaktioner ved at trykke på huden og føle efter, om der er hårde buler.
English: 60 vials of Water for Injections that is used to reconstitute the Fuzeon powder 60 3 ml syringes
Danish: 60 hætteglas vand til injektionsvæsker, som anvendes til rekonstituering af Fuzeon pulver 60 3 ml sprøjter
English: • If foaming happens, it may take longer for the powder to dissolve completely.
Danish: • Hvis det begynder at skumme, tager det længere tid, inden pulveret er helt opløst.
English: Very common (affects more than 1 in 10 people)
Danish: Meget almindelige (påvirker flere end 1 ud af 10 brugere)
English: The virus needs to make contact with, and get inside these cells in order for the virus to multiply.
Danish: For at kunne dele sig skal virus skabe kontakt til og kunne komme ind i disse celler.
English: The solvent vials contain 2 ml Water for Injections, of which 1.1 ml must be withdrawn for the reconstitution of the powder.
Danish: Hætteglasset med solvens indeholder 2 ml med vand til injektionsvæsker, hvoraf 1,1 ml skal anvendes til rekonstituering af pulveret.
English: - Make sure you have 1.0 ml of liquid in the syringe (or whatever amount your doctor prescribed, if it is different).
Danish: • Vær sikker på, der er 1,0 ml opløsning i sprøjten (eller den mængde, lægen har ordineret).
English: Hypersensitivity reactions have occasionally been associated with therapy with enfuvirtide and in rare cases hypersensitivity reactions have recurred on rechallenge.
Danish: Overfølsomhedsreaktioner er lejlighedsvis blevet relateret til behandlingen med enfuvirtid, og i sjældne tilfælde er hypersensitivitetsreaktionerne dukket op igen ved provokationsforsøg.
English: In deciding on a new regimen for patients who have failed an antiretroviral regimen, careful consideration should be given to the treatment history of the individual patient and the patterns of mutations associated with different medicinal products.
Danish: Beslutningen om en ny behandling af patienter, som ikke har responderet på antiretroviral behandling, bør træffes efter omhyggelige overvejelser om tidligere behandling af den enkelte patient og resistensmønster associeret med forskellige lægemidler.
English: METHOD AND ROUTE(S) OF ADMINISTRATION Subcutaneous use
Danish: ANVENDELSESMÅDE OG ADMINISTRATIONSVEJ(E) Subkutan anvendelse
English: Studies in Antiretroviral Experienced Patients: The clinical activity of Fuzeon (in combination with other antiretroviral agents) on plasma HIV RNA levels and CD4 counts have been investigated in two randomised, multicentre, controlled studies (TORO 1 and TORO 2) of Fuzeon of 48 weeks duration.
Danish: Studier af patienter, som tidligere har været i behandling med antiretrovirale lægemidler: Fuzeons kliniske aktivitet (i kombination med andre antiretrovirale stoffer) på plasma-hiv-RNAkoncentrationer og CD4-tal er undersøgt i to randomiserede, kontrollerede multicenterstudier (TORO 1 og TORO 2) af 48 ugers varighed.
English: ● Never use a syringe with a bent or damaged needle.
Danish: • Brug aldrig en bøjet eller ødelagt nål.
English: PHARMACEUTICAL FORM AND CONTENTS Solvent for parenteral use
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) Solvens til parenteral anvendelse
English: A statistically significant increase was seen for pneumonia and lymphadenopathy.
Danish: Der blev set en statistisk signifikant stigning mht. pneumoni og lymfadenopati.
English: Fuzeon + OB 90 mg bid (N=661)
Danish: Fuzeon + OB 90 mg 2 gange daglig (N=661)
English: 6.6 Special precautions for disposal and reconstitution
Danish: 6.6 Regler for destruktion og rekonstitution
English: A vial is suitable for single use only; unused portions must be discarded.
Danish: Et hætteglas må kun bruges én gang og ikke anvendt opløsning skal bortskaffes.
English: Patient demographics include a median baseline HIV-1 RNA of 5.2 log10 copies/ml and 5.1 log10 copies/ml and median baseline CD4 cell count of 88 cells/mm3 and 97 cells/mm3 for Fuzeon + OB and OB, respectively.
Danish: Patientdemografien inkluderer en median baseline-hiv-1-RNA på 5,2 log10 kopier/ml og 5,1 log10 kopier/ml og et mediant baseline-CD4 celletal på 88 celler/mm3 og 97 celler/mm3 for hhv.
English: When using a higher threshold for eosinophilia (>1.4 x 109/l), the patient exposure adjusted rate of eosinophilia is equal in both groups (1.8 patients with event per 100 patientyears).
Danish: Ved anvendelse af en højere grænseværdi for eosinofili (> 1,4 x 109/l) var den patienteksponeringsjusterede hyppighed af eosinofili den samme i begge grupper (1,8 patienter med uønskede hændelser pr. 100 patientår).
English: GENERAL CLASSIFICATION FOR SUPPLY Medicinal product subject to medical prescription
Danish: GENEREL KLASSIFIKATION FOR UDLEVERING Receptpligtigt lægemiddel.
English: Influence of enfuvirtide on metabolism of concomitant medicinal products: In an in-vivo human metabolism study enfuvirtide, at the recommended dose of 90 mg twice daily, did not inhibit the metabolism of substrates by CYP3A4 (dapsone), CYP2D6 (debrisoquine), CYP1A2 (caffeine), CYP2C19 (mephenytoin), and CYP2E1 (chlorzoxazone).
Danish: Enfuvirtids indvirkning på metabolismen af samtidigt indgivne lægemidler: I et humant in-vivometabolismestudie hæmmede enfuvirtid ved den anbefalede dosis på 90 mg to gange dagligt ikke metabolismen af lægemidler, som er substrater for CYP3A4 (dapson), CYP2D6 (debrisoquin), CYP1A2 (koffein), CYP2C19 (mefenytoin) og CYP2E1 (chlorzoxazon).
English: As a peptide, enfuvirtide can cause cutaneous amyloidosis at the injection site.
Danish: Som et peptid, kan enfuvirtid forårsage kutan amyloidose på injektionsstedet.
English: Your syringes
Danish: Dine sprøjter
English: Always use this medicine exactly as your doctor or pharmacist has told you.
Danish: Brug altid dette lægemiddel nøjagtigt efter lægens eller apotekspersonalets anvisning.
English: Fuzeon is indicated in combination with other antiretroviral medicinal products for the treatment of HIV-1 infected patients who have received treatment with and failed on regimens containing at least one medicinal product from each of the following antiretroviral classes: protease inhibitors, nonnucleoside reverse transcriptase inhibitors and nucleoside reverse transcriptase inhibitors, or who have intolerance to previous antiretroviral regimens (see section 5.1).
Danish: Fuzeon er i kombination med andre antiretrovirale lægemidler indiceret til behandling af hiv-1smittede patienter, som er behandlet med, og som ikke har responderet på mindst et lægemiddel fra en af følgende antiretrovirale lægemiddelgrupper: proteasehæmmere, non-nukleosid reverse transkriptasehæmmere og nukleosid reverse transkriptasehæmmere, eller som ikke har tolereret tidligere antiretrovirale regimer (se pkt.
English: ● Wash your hands well.
Danish: Tips om sikkerheden  Vask hænderne grundigt.
English: Fuzeon contains sodium Fuzeon contains less than 1 mmol sodium (23 mg) per dose, i.e. it is essentially ‘sodium-free'.
Danish: Fuzeon indeholder mindre end 1 mmol natrium (23 mg) per dosis, hvilket vil sige, at det stort set er natriumfrit.
English: BATCH NUMBER Batch
Danish: FREMSTILLERENS BATCHNUMMER Batch
English: Paediatric population: The pharmacokinetics of enfuvirtide have been studied in 37 paediatric patients.
Danish: Pædiatrisk population: Enfuvirtids farmakokinetik er undersøgt hos 37 børn.
English: Studies in guinea pigs indicated a potential for enfuvirtide to produce delayed contact hypersensitivity.
Danish: Studier med marsvin tyder på, at enfuvirtid potentielt kan udløse en forsinket kontaktoverfølsomhedsreaktion.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C to 8°C, unless reconstitution has taken place in controlled and validated aseptic conditions.
Danish: De må normalt ikke overskride 24 timer ved 2 °C til 8 °C, medmindre rekonstituering har fundet sted under kontrollerede og validerede aseptiske betingelser.
English: Speak with your doctor if you have a history of liver disease.
Danish: Tal med lægen, hvis du tidligere har haft en leversygdom.
English: 15.6 to 20.0
Danish: 15,6 til 20,0
English: Table 4: Exposure adjusted Grade 3 & 4 laboratory abnormalities among patients on Fuzeon+OB and OB alone regimens, reported at more than 2 patients with event per 100 patient years Laboratory Parameters Grading
Danish: Tabel 4: Eksponeringsjusterede laboratorieanomalier af grad 3 & 4 hos patienter i behandling med Fuzeon + OB og OB alene, som rapporteredes hos mere end 2 patienter pr. 100 patientår Laboratorieparameter Graduering
English: Do this in a circular motion, starting in the middle and working outward.
Danish: Bevæg servietten i cirkler, startende i midten og arbejd dig udad.
English: To make sure that the needle is firmly on the syringe:
Danish: For at sikre, at nålen sidder rigtigt fast på sprøjten, skal du:
English: Detailed information on this medicinal product is available on the web site of the European Medicines Agency: http://www.ema.europa.eu/
Danish: Du kan finde yderligere oplysninger om dette lægemiddel på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu.
English: Antiviral activity in vitro: The susceptibility to enfuvirtide of 612 HIV recombinants containing the env genes from HIV RNA samples taken at baseline from patients in Phase III studies gave a geometric mean EC 50 of 0.259 µg/ml (geometric mean + 2SD = 1.96 µg/ml) in a recombinant phenotype HIV entry assay.
Danish: Antiviral aktivitet in vitro: Den geometriske middel EC50 for følsomheden af 612 hiv-rekombinanter indeholdende env-gener fra hiv-RNA-prøver taget ved baseline fra patienter i fase III-studier var 0,259 µg/ml (geometrisk middeltal + 2SD = 1,96 µg/ml) i et rekombinant fænotype hiv-assay.
English: Once reconstituted, the solution should be injected immediately.
Danish: Når det er rekonstitueret, skal opløsningen injiceres med det samme.
English: Renal impairment: Analysis of plasma concentration data from patients in clinical trials indicated that the clearance of enfuvirtide is not affected to any clinically relevant extent in patients with mild to moderate renal impairment.
Danish: Nedsat nyrefunktion: Analyser af plasmakoncentrationsdata fra patienter i kliniske forsøg tyder på, at enfuvirtids clearance ikke påvirkes klinisk relevant hos patienter med mild til moderat nyreinsufficiens.
English: Patients must be instructed to add the water for injections and then gently tap the vial with their fingertip until the powder begins to dissolve.
Danish: Patienten skal instrueres i at tilsætte vandet til injektionen og forsigtig banke på hætteglasset med fingerspidsen, indtil pulveret begynder at opløses.
English: Enfuvirtide also inhibited HIV-1 envelope mediated cell-cell fusion.
Danish: Enfuvirtid hæmmede også hiv-1-viruspartiklers celle-celle medierede fusion.
English: - This step may be repeated until the correct amount of solution is in the syringe.
Danish: • Dette trin kan gentages, indtil du har fået den rigtige mængde opløsning op i sprøjten.
English: In HIV-infected patients with severe immune deficiency at the time of initiation of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Danish: Hos hiv-smittede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske infektioner.
English: Frequency categories are defined using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Danish: (≥ 1/10), almindelig (≥ 1/100 til < 1/10), ikke almindelig (≥ 1/1.000 til < 1/100), sjælden (≥ 1/10.000
English: Pick up the 3 ml large syringe.
Danish: Tag den store 3 ml sprøjte.
English: In Vivo resistance to enfuvirtide: In phase III clinical studies HIV recombinants containing the env genes from HIV RNA samples taken up to week 24 from 187 patients showed > 4 fold reduced susceptibility to enfuvirtide compared with the corresponding pre-treatment samples.
Danish: In vivo-resistens overfor enfuvirtid: I kliniske fase III-studier viste hiv-rekombinanter, indeholdende env-gener fra hiv-RNA-prøver taget op til uge 24 fra 187 patienter, > 4 gange nedsat følsomhed overfor enfuvirtid sammenlignet med tilsvarende prøver taget før behandlingen.
English: Any unused medicinal product should be disposed of in accordance with local requirements.
Danish: Ikke anvendt lægemiddel samt affald heraf skal bortskaffes i henhold til lokale retningslinjer.
English: In a renal impairment study AUC of enfuvirtide was increased on average by 43-62% in patients with severe or end stage renal disease compared to patients with normal renal function.
Danish: I et studie, hvor patienter med nyreinsufficiens blev sammenlignet med patienter med normal nyrefunktion, var enfuvirtids AUC i gennemsnit øget med 43-62 % hos patienter med svær nyreinsufficiens eller hos patienter med nyresygdom i slutfasen.
English: To remove the clear plastic cap: • push towards the syringe and then pull the cap off.
Danish: Fjern den klare plastikhætte ved at: • trykke hætten ned mod sprøjten og derefter trække hætten af.
English: Rarely, you may get an infection at a place where an individual injection was given.
Danish: Du kan i sjældne tilfælde opleve at få en infektion på indsprøjtningsstedet.
English: 1 ml of the reconstituted solution should be injected subcutaneously in to the upper arm, abdomen or anterior thigh.
Danish: 1 ml af den rekonstituerede opløsning skal injiceres subkutant i overarmen, abdomen eller lårets forside.
English: - If the bubbles are still there, gently tap the side of the vial to help settle them.
Danish: • Hvis boblerne bliver ved med at være der, kan du banke let på hætteglassets side for at få dem til at forsvinde.
English: If you forget to use Fuzeon
Danish: Hvis du har glemt at tage Fuzeon
English: Influence of concomitant medicinal products on enfuvirtide metabolism: In separate pharmacokinetic interaction studies, co-administration of ritonavir (potent CYP3A4 inhibitor) or saquinavir in combination with a booster dose of ritonavir or rifampicin (potent CYP34A inducer) did not result in clinically significant changes of the pharmacokinetics of enfuvirtide.
Danish: Indvirkning af samtidigt indgivne lægemidler på enfuvirtids metabolisme: I separate farmakokinetiske interaktionsstudier medførte samtidig administration af ritonavir (potent CYP3A4-hæmmer) eller saquinavir i kombination med en støddosis af ritonavir eller rifampicin (potent CYP3A4-induktor) ingen klinisk signifikante ændringer af enfuvirtids farmakokinetik.
English: Press the syringe plunger in slowly.
Danish: Tryk langsomt stemplet ned.
English: In 25 paediatric patients ranging in age from 5 to 16 years and receiving the 2 mg/kg bid dose into the upper arm, anterior thigh or abdomen, the mean steady-state AUC was 54.3 ± 23.5 µg*h/ml, Cmax was 6.14 ± 2.48 µg/ml, and Ctrough was 2.93 ± 1.55 µg/ml.
Danish: Hos 25 børn i alderen 5 til 16 år, som fik 2 mg/kg to gange dagligt i overarmen, på lårets forside eller i abdomen, var middel-AUC i steady state 54,3 ± 23,5 µg*time/ml, Cmax var 6,14 ± 2,48 µg/ml og Ctrough var 2,93 ± 1,55 µg/ml.
English: ● Never inject your medicine with other injectable medicines.
Danish:  Giv aldrig indsprøjtningen sammen med anden medicin, der skal indsprøjtes.
English: Infections and infestations Common
Danish: Infektioner og parasitære sygdomme Almindelig
English: Cross-resistance: Due to its novel viral target enfuvirtide is equally active in vitro against both wildtype laboratory and clinical isolates and those with resistance to 1, 2 or 3 other classes of antiretrovirals (nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors).
Danish: Krydsresistens: På grund af det nye virale angrebspunkt er enfuvirtid lige aktivt in vitro over for wildtype laboratorieisolater som kliniske isolater samt over for isolater, som er resistente over for en, to eller tre andre klasser af antiretrovirale lægemidler (nukleosid reverse transkriptasehæmmere, nonnukleosid reverse transkriptasehæmmere og proteasehæmmere).
English: If you stop using Fuzeon
Danish: Hvis du holder op med at tage Fuzeon
English: Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported; however, the reported time to onset is more variable and these events can occur many months after initiation of treatment (see section 4.4).
Danish: Autoimmune lidelser (såsom Graves sygdom og autoimmun hepatitis) er også set; tiden til udbrud er mere variabel og kan være mange måneder efter initiering af behandling (se pkt.
English: Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines.
Danish: Fortæl altid lægen, apotekspersonalet eller sundhedspersonalet om du bruger anden medicin eller har gjort det for nylig.
English: Where available, resistance testing may be appropriate (see sections 4.4 and 5.1).
Danish: Om muligt kan det være hensigtsmæssig med resistenstestning (se pkt.
English: What Fuzeon looks like and contents of the pack Fuzeon powder and solvent for solution for injection comes in a carton containing:
Danish: Udseende og pakningsstørrelser Fuzeon pulver og solvens til injektionsvæske, opløsning leveres i en pakning, som indeholder:
English: ● Do not use opened materials.
Danish:  Brug ikke medicin, som har været åbnet.
English: Patients with chronic hepatitis B or C and treated with anti-HIV therapy are at an increased risk for serious liver problems.
Danish: Patienter med kronisk hepatitis B eller C, som behandles med hiv-medicin, har øget risiko for alvorlige leverproblemer.
English: Table 3: Summary of individual signs/symptoms characterising local injection site reactions in studies TORO 1 and TORO 2 combined (% of patients) n=663
Danish: Tabel 3: Resumé af individuelle symptomer, der karakteriserer lokale reaktioner på injektionsstedet i studierne TORO 1 og TORO 2 tilsammen (% af patienter)
English: Take out the needle from the vial.
Danish: Træk nålen ud af hætteglasset.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 108 mg enfuvirtide
Danish: INDHOLDSMÆNGDE ANGIVET SOM VÆGT, VOLUMEN ELLER ANTAL DOSER 108 mg enfuvirtid
English: Laboratory abnormalities
Danish: Laboratorieanomalier
English: Not applicable
Danish: Ikke relevant.
English: Patients with chronic hepatitis B and C and treated with antiretroviral therapy are at an increased risk for severe and potentially fatal hepatic adverse events.
Danish: Patienter med kronisk hepatitis B og C, som behandles med antiretroviral terapi har en forhøjet risiko for alvorlige og potentielt dødelige leverbivirkninger.
English: If you have any questions or concerns about the safe disposal of these materials, please talk to your doctor, pharmacist or nurse.
Danish: Hvis du har spørgsmål, eller der er noget, du er usikker på vedrørende bortskaffelse af brugte materialer, skal du kontakte lægen, apotekspersonalet eller sundhedspersonalet.
English: • acne
Danish: • akne
English: Some patients taking combination anti-HIV medicines may develop a bone disease called osteonecrosis.
Danish: Nogle af de patienter, der får flere former for hiv-medicin på samme tid, kan udvikle en knoglesygdom, der kaldes knoglenekrose.
English: Never shake the vial or turn it upside down to mix-this will cause too much foaming.
Danish: Du må aldrig ryste hætteglasset eller vende det op og ned for at blande - det vil skumme for meget.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation:
Danish: DATO FOR FØRSTE MARKEDSFØRINGSTILLADELSE/FORNYELSE AF TILLADELSEN
English: - After washing your hands, do not touch anything except the injection supplies and where the injection will be given.
Danish: • Efter du har vasket hænder, må du ikke røre ved noget, bortset fra det du skal bruge til indsprøjtningen, og dér hvor indsprøjtningen skal gives Rengør toppen af hætteglassene
English: ● Do not inject Fuzeon into your veins (‘intravenously') or into your muscles (‘intramuscularly').
Danish: • Fuzeon må ikke indsprøjtes i en blodåre (intravenøst) eller i en muskel (intramuskulært).
English: Safety data mainly refer to 48-week data from studies TORO 1 and TORO 2 combined (see section 5.1).
Danish: Sikkerhedsprofilen baserer sig primært på 48-ugers data kombineret fra studierne TORO 1 og TORO 2 (se pkt.
English: Contents of the pack and other information Step-by-step guide to injecting Fuzeon
Danish: Pakningsstørrelser og yderligere oplysninger Trin for trin vejledning til indsprøjtning af Fuzeon
English: • The recommended dose is 90 mg twice a day for adults and adolescents (16 years and older).
Danish: • Den anbefalede dosis til voksne og unge (16 år og derover) er 90 mg to gange daglig
English: They must never shake the vial or turn it upside down to mix-this will cause excessive foaming.
Danish: Man må aldrig ryste eller vende hætteglasset op og ned for at blande - dette vil forårsage skumdannelse.
English: 24.6 to 29.0
Danish: 24,6 til 29,0
English: Through week 48, eosinophilia [greater than the Upper Limit of Normal of > 0.7 x 109/l] occurred at a higher rate amongst patients in the Fuzeon containing group (12.4 patients with event per 100 patient-years) compared with OB alone regimen (5.6 patients with event per 100 patient-years).
Danish: I uge 48 optrådte eosinofili [højere end øvre normalgrænse (ULN) dvs. > 0,7 x 109/l] hyppigere hos patienter i gruppen, som fik Fuzeon (12,4 patienter pr. 100 patientår) sammenlignet med patienter, som fik OB alene (5,6 patienter pr. 100 patientår).
English: Pack sizes
Danish: Pakningsstørrelser
English: CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Danish: B. BETINGELSER ELLER BEGRÆNSNINGER VEDRØRENDE UDLEVERING OG ANVENDELSE
English: No dose adjustment is required for patients with impaired renal function.
Danish: Dosisjustering er ikke nødvendig hos patienter med nedsat nyrefunktion.
English: Roche Registration GmbH Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany
Danish: Roche Registration GmbH Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Tyskland
English: • Fuzeon is given as a 1 ml injection just below the skin - called a ‘subcutaneous' injection.
Danish: • Fuzeon gives som en 1 ml indsprøjtning lige under huden - dette kaldes en subkutan injektion.
English: Common (affects less than 1 in 10 people)
Danish: Almindelige (påvirker mindre end 1ud af 10 brugere)
English: How to prepare and inject Fuzeon
Danish: Sådan klargør og indsprøjter du Fuzeon
English: 33.6 to 38.0
Danish: 33,6 til 38,0
English: Dose per bid injection (mg/dose)
Danish: Dosis pr. injektion, som gives to gange dagligt (mg/dosis)
English: Wipe the top of the Fuzeon vial again with a new alcohol swab.
Danish: Rengør toppen af hætteglasset med Fuzeon igen med en ny spritserviet.