FrancophonIA/ELRC3.0 huggingface dataset:
English: • if you have recently experienced a myocardial infarction (heart attack), or if you are suffering from congestive heart failure or from an uncontrolled hypertension (high blood pressure).
Bulgarian: - če ste v preteklosti imeli epileptične napade, - če ste pred kratkim preboleli srčni infarkt (srčno kap), imate kongestivno srčno popuščanje ali neurejeno hipertenzijo (visok krvni tlak).
English: Therapy should only be started if a caregiver is available who will regularly monitor the intake of the medicinal product by the patient.
Bulgarian: Zdravljenje naj se začne le v primeru, če je na voljo ustrezna oseba, ki za bolnika skrbi in ki lahko nadzoruje bolnikovo redno jemanje zdravila.
English: From the fourth week on, the usual dose is 2 tablets once a day (1 x 20 mg).
Bulgarian: Od četrtega tedna naprej je običajen odmerek 2 tableti enkrat dnevno (1 x 20 mg).
English: • Concomitant use of memantine and amantadine should be avoided, owing to the risk of pharmacotoxic psychosis.
Bulgarian: Sočasni uporabi memantina in amantadina se je potrebno izogniti, ker lahko pride do pojava farmakotoksične psihoze.
English: The most frequently occurring adverse reactions with a higher incidence in the memantine group than in the placebo group were dizziness (6.3% vs 5.6%, respectively), headache (5.2% vs 3.9%), constipation (4.6% vs 2.6%), somnolence (3.4% vs 2.2%) and hypertension (4.1% vs 2.8%).
Bulgarian: kot pri skupini, ki je prejemala placebo, so bili omotica (6,3 % proti 5,6 %), glavobol (5,2 % proti 3,9 %), zaprtje (4,6 % proti 2,6 %), zaspanost (3,4 % proti 2,2 %)
English: If you go into hospital, let your doctor know that you are taking Memantine LEK.
Bulgarian: V primeru, da ste sprejeti v bolnišnico, obvestite zdravnika, da jemljete zdravilo Memantin LEK.
English: For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
Bulgarian: Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
English: Main human metabolites are N-3,5-dimethyl-gludantan, the isomeric mixture of 4-and 6-hydroxy-memantine, and 1-nitroso-3,5-dimethyl-adamantane.
Bulgarian: Pri človeku so naqjpomembnejši presnovki N-3,5-dimetil-gludantan, izomerna mešanica 4- in 6-hidroksi-memantina in 1-nitrozo-3,5-dimetil-adamantana.
English: The renal elimination rate of memantine under alkaline urine conditions may be reduced by a factor of 7 to 9 (see section 4.4).
Bulgarian: Pri alkalnem urinu lahko pride do za 7- do 9-krat zmanjšane hitrosti izločanja memantina (glejte poglavje 4.4).
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu.
Bulgarian: Podrobni podatki o tem izdelku so na voljo na spletni strani Evropske agencije za zdravila (EMA) http://www.ema.europa.eu.
English: The use of memantine in pregnant women is not recommended.
Bulgarian: Uporaba memantina pri nosečnicah ni priporočljiva.
English: Caution is recommended in patients with epilepsy, former history of convulsions or patients with predisposing factors for epilepsy.
Bulgarian: Previdnost se priporoča pri bolnikih z epilepsijo, s krči v anamnezi ali pri bolnikih z nagnjenostijo k epilepsiji.
English: Maintenance dose
Bulgarian: Vzdrževalni odmerek
English: What is Memantine LEK used for Memantine LEK is used for the treatment of adult patients with moderate to severe Alzheimer's disease.
Bulgarian: Za kaj uporabljamo zdravilo Memantin LEK Zdravilo Memantin LEK uporabljamo za zdravljenje odraslih bolnikov z zmerno do hudo Alzheimerjevo boleznijo.
English: In the event of overdose, treatment should be symptomatic.
Bulgarian: Zdravljenje Pri prevelikem odmerjanju je potrebno simptomatsko zdravljenje.
English: • In post-marketing experience, isolated cases with international normalized ratio (INR) increases have been reported in patients concomitantly treated with warfarin.
Bulgarian: • V okviru izkušenj iz obdobja trženja so poročali o posameznih primerih povečanja mednarodnega umerjenega razmerja (INR) pri bolnikih, ki so bili sočasno zdravljeni z varfarinom.
English: If you have impaired kidney function, your doctor will decide upon a dose that suits your condition.
Bulgarian: Če imate ledvično okvaro, vam bo zdravnik prilagodil odmerek v skladu z vašim stanjem.
English: Ask your pharmacist how to throw away medicines you no longer use.
Bulgarian: O načinu odstranjevanja zdravila, ki ga ne uporabljate več, se posvetujte
English: In a clinical study in young healthy subjects, no relevant effect of memantine on the pharmacokinetics of galantamine was observed.
Bulgarian: V klinični raziskavi pri mladih zdravih osebah niso opazili pomembnega vpliva memantina na farmakokinetiko galantamina.
English: MARKETING AUTHORISATION NUMBER(S)
Bulgarian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ)
English: Furthermore, Memantine LEK has minor or moderate influence on the ability to drive and use machines such that outpatients should be warned to take special care.
Bulgarian: Prav tako ima zdravilo Memantin LEK blag do zmeren vpliv na sposobnost vožnje in upravljanja strojev, zato je potrebno bolnike opozoriti na posebno previdnost.
English: The patient had received 400 mg memantine orally.
Bulgarian: Peroralno je dobil 400 mg memantina.
English: In this case, monitoring of your kidney function should be performed by your doctor at specified intervals.
Bulgarian: V teh primerih bo zdravnik nadzoroval ledvično delovanje v določenih časovnih presledkih.
English: The use of medicinal products called amantadine (for the treatment of Parkinson's disease), ketamine (a substance generally used as an anaesthetic), dextromethorphan (generally used to treat cough) and other NMDA-antagonists at the same time should be avoided.
Bulgarian: Izogibati se je treba sočasni uporabi zdravil, kot so amantadin (za zdravljenje Parkinsonove bolezni), ketamin (običajno se uporablja kot anestetik), dekstrometorfan (običajno se uporablja za zdravljenje kašlja) in ostali zaviralci receptorjev NMDA.
English: Renal handling also involves tubular reabsorption, probably mediated by cation transport proteins.
Bulgarian: V ledvicah poteka tudi tubularna reabsorpcija, verjetno preko beljakovinskega kationskega transporta.
English: Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Bulgarian: s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: 1Hallucinations have mainly been observed in patients with severe Alzheimer's disease.
Bulgarian: 1Halucinacije so bile večinoma opažene pri bolnikih
English: Memantine LEK belongs to a group of medicines known as anti-dementia medicines.
Bulgarian: Zdravilo Memantin LEK sodi v skupino zdravil, znanih kot zdravila za zdravljenje demence.
English: Both active substances are chemically related NMDA-antagonists.
Bulgarian: Obe učinkovini sta kemijsko sorodna antagonista NMDA.
English: Daily doses of 20 mg lead to steady-state plasma concentrations of memantine ranging from 70 to 150 ng/mL (0.5 - 1 μmol) with large interindividual variations.
Bulgarian: Ob dnevnih odmerkih 20 mg so v stanju dinamičnega ravnovesja dosežene plazemske koncentracije memantina od 70 do 150 ng/ml (0,5 - 1 µmol), z veliko variabilnostjo med posamezniki.
English: Concomitant administration of memantine with the antispasmodic medicinal products, dantrolene or baclofen, can modify their effects and a dose adjustment may be necessary.
Bulgarian: Sočasno dajanje memantina in spazmolitikov, dantrolena ali baklofena lahko spremeni njihove učinke, zato bo morda potrebno prilagoditi odmerke.
English: Memantine LEK with food and drink
Bulgarian: s hrano in pijačo
English: PHARMACEUTICAL FORM Film-coated tablet.
Bulgarian: FARMACEVTSKA OBLIKA filmsko obložena tableta
English: Other medicines and Memantine LEK
Bulgarian: Druga zdravila in zdravilo Memantin LEK
English: INSTRUCTIONS ON USE
Bulgarian: NAVODILA ZA UPORABO
English: Maintenance treatment can be continued for as long as a therapeutic benefit is favourable and the patient tolerates treatment with memantine.
Bulgarian: vzdrževalnim zdravljenjem lahko nadaljujemo, dokler obstaja korist za bolnika in dokler bolnik zdravljenje prenaša.
English: What Memantine LEK is and what it is used for
Bulgarian: Kaj je zdravilo Memantin LEK in za kaj ga uporabljamo
English: From Week 4 on (day 22-28):
Bulgarian: teden (15.-21. dan):
English: Animal studies indicate a potential for reducing intrauterine growth at exposure levels, which are identical or slightly higher than at human exposure (see section 5.3).
Bulgarian: V študijah na živalih so ugotovili, da memantin lahko zavira intrauterino rast pri izpostavljenosti, ki je enaka ali le malo višja od izpostavljenosti pri ljudeh (glejte poglavje 5.3).
English: A. LABELLING
Bulgarian: OZNAČEVANJE
English: Memantine LEK belongs to a group of medicines called NMDA-receptor antagonists.
Bulgarian: Zdravilo Memantin LEK spada v skupino zdravil, ki se imenujejo antagonisti receptorjev NMDA.
English: In rats, foetal growth reduction was noted at exposure levels, which are identical or slightly higher than at human exposure.
Bulgarian: Pri podganah so ugotovili zmanjšano rast ploda v odmerkih, ki so bili primerljivi ali malo višji kot pri ljudeh.
English: Venous thrombosis/thromboembolism
Bulgarian: Občasni venska tromboza/tromboembolija
English: Reporting of suspected adverse reactions
Bulgarian: Poročanje o domnevnih neželenih učinkih
English: Do not use this medicine after the expiry date which is stated on the carton and the blister after EXP.
Bulgarian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na pretisnem omotu poleg oznake EXP. Datum izteka roka uporabnosti se nanaša na zadnji dan navedenega meseca.
English: The patient experienced central nervous system symptoms such as restlessness, psychosis, visual hallucinations, proconvulsiveness, somnolence, stupor, and unconsciousness.
Bulgarian: s centralnim živčnim sistemom, kot so nemir, psihoza, vidne halucinacije, nagnjenost h konvulzijam, zaspanost, stupor in nezavest.
English: • Headache, sleepiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high blood pressure and drug hypersensitivity
Bulgarian: glavobol, zaspanost, zaprtje, zvišane vrednosti testov jetrne funkcije, omotica, motnje ravnotežja, zasoplost, visok krvni tlak in preobčutljivost za zdravilo
English: Somnolence Confusion Hallucinations1
Bulgarian: Občasni halucinacije1
English: Dose in patients with impaired kidney function
Bulgarian: Odmerek pri bolnikih z ledvično okvaro
English: What Memantine LEK is and what it is used for What you need to know before you take Memantine LEK How to take Memantine LEK Possible side effects
Bulgarian: Kaj je zdravilo Memantin LEK in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Memantin LEK Kako jemati zdravilo Memantin LEK
English: How to store Memantine LEK Contents of the pack and other information
Bulgarian: Shranjevanje zdravila Memantin LEK Vsebina pakiranja in dodatne informacije
English: 4.4 Special warnings and precautions for use
Bulgarian: 4.4 Posebna opozorila in previdnostni ukrepi
English: Like all medicines, this medicine can cause side effects, although not everybody gets them.
Bulgarian: ima lahko tudi to zdravilo neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: In clinical trials in mild to severe dementia, involving 1,784 patients treated with memantine and 1,595 patients treated with placebo, the overall incidence rate of adverse reactions with memantine did not differ from those with placebo; the adverse reactions were usually mild to moderate in severity.
Bulgarian: V kliničnih preskušanjih bolnikov z zmerno do hudo demenco, ki so zajeli 1784 bolnikov, zdravljenih z memantinom in 1595 bolnikov, ki so prejemali placebo, se skupna incidenca neželenih učinkov pri memantinu ni razlikovala od placeba, neželeni učinki pa so bili po resnosti večinoma blagi do zmerni.
English: Elimination
Bulgarian: Izločanje
English: • Tiredness, fungal infections, confusion, hallucinations, vomiting, abnormal gait, heart failure and venous blood clotting (thrombosis/thromboembolism)
Bulgarian: utrujenost, glivična okužba, zmedenost, halucinacije, bruhanje, neobičajna hoja, odpoved srca in krvni strdki v venah (tromboza/tromboembolija)
English: Memantine is a voltage-dependent, moderate-affinity uncompetitive NMDA-receptor antagonist.
Bulgarian: Memantin je napetostno odvisni, nekompetitivni antagonist receptorjev NMDA z zmerno afiniteto.
English: 4.2 Posology and method of administration
Bulgarian: 4.2 Odmerjanje in način uporabe
English: In single-dose pharmacokinetic (PK) studies in young healthy subjects, no relevant active substance - active substance interaction of memantine with glyburide/metformin or donepezil was observed.
Bulgarian: V raziskavah farmakokinetike (PK) posameznega odmerka pri mladih zdravih osebah ni bilo opaziti interakcij memantina z gliburidom/metforminom ali donepezilom.
English: Specific ophthalmoscopic examinations in clinical studies with memantine did not disclose any ocular changes.
Bulgarian: Specifične oftalmoskopske preiskave v raziskavah z memantinom niso razkrile
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Bulgarian: so navedene na seznamu referenčnih datumov Unije (seznam EURD), predvidenega v členu 107c (7) Direktive
English: This includes any possible side effects not listed in this leaflet.
Bulgarian: Posvetujte se tudi, če opazite katere koli neželene učinke, ki niso navedeni v tem navodilu.
English: The usual starting dose is half a tablet of 10 mg once a day (1x 5 mg) for the first week.
Bulgarian: Običajni začetni odmerek je polovica 10 mg tablete enkrat dnevno (1 x 5 mg) v prvem tednu.
English: one and a half 10 mg tablets week 4 and beyond two 10 mg tablets or one 20 mg tablet once a day
Bulgarian: teden in naprej dve 10 mg tableti ali ena 20 mg tableta enkrat dnevno
English: 6.4 Special precautions for storage
Bulgarian: 6.4 Posebna navodila za shranjevanje
English: This is increased to one tablet of 10 mg once a day (1x 10 mg) in the second week and to 1 and a half tablet of 10 mg once a day in the third week.
Bulgarian: V drugem tednu povišamo odmerek na eno 10 mg tableto enkrat dnevno (1 x 10 mg) in v tretjem tednu na 1 in ½ 10 mg tablete enkrat dnevno.
English: • Risk Management Plan (RMP)
Bulgarian: Načrt za obvladovanje tveganja (RMP) Navedba smiselno ni potrebna.
English: The recommended maintenance dose is 20 mg per day.
Bulgarian: Priporočeni vzdrževalni odmerek je 20 mg na dan.
English: Psychiatric disorders
Bulgarian: Psihiatrične motnje
English: If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Bulgarian: Če imate dodatna vprašanja o uporabi zdravila, se posvetujte
English: In order to reduce the risk of undesirable effects the maintenance dose is achieved by upward titration of 5 mg per week over the first 3 weeks as follows:
Bulgarian: Da bi zmanjšali pojavnost neželenih učinkov, je potrebno postopno zviševanje odmerka po 5 mg na teden v prvih treh tednih zdravljenja, dokler ni dosežen vzdrževalni odmerek, kot sledi:
English: In volunteers with normal kidney function, total clearance (Cltot) amounts to 170 mL/min/1.73 m² and part of total renal clearance is achieved by tubular secretion.
Bulgarian: s končnim razpolovnim časom (t½) od 60 do 100 ur. Pri prostovoljcih z normalnim delovanjem ledvic je celoten očistek (Cltot) 170 ml/min/1,73 m²; del celotnega ledvičnega očistka je dosežen
English: When patients were identified with concurrent worsening in all three domains, results showed a statistically significant effect of memantine in preventing worsening, as twice as many placebo-treated patients as memantine-treated patients showed worsening in all three domains (21% vs. 11%,p<0.0001).
Bulgarian: Pri bolnikih, kjer so ocenili hkratno poslabšanje vseh treh področji, so rezultati pokazali statistično značilen učinek memantina pri preprečevanju poslabšanja, saj se je pri dvakrat več bolnikih, ki so prejemali placebo, kot pri bolnikih, zdravljenih z memantinom, pokazalo poslabšanje na področju vseh treh področji (21
English: There are no or limited amount of data from the use of memantine in pregnant women.
Bulgarian: Podatkov o uporabi memantina pri nosečnicah ni oziroma so omejeni.
English: In patients with mildly impaired renal function (creatinine clearance 50 - 80 mL/min) no dose adjustment is required.
Bulgarian: Pri bolnikih z blago okvaro delovanja ledvic (očistek kreatinina 50 - 80 ml/min) prilagoditev odmerka ni potrebna.
English: The tablets can be taken with or without food.
Bulgarian: s hrano ali brez nje.
English: Iron oxide yellow (E 172) Iron oxide red (E 172)
Bulgarian: smukec rumeni železov oksid (E 172) rdeči železov oksid (E 172)
English: Phospholipidosis in pulmonary macrophages due to accumulation of memantine in lysosomes was observed in rodents.
Bulgarian: Pri glodalcih so opazili fosfolipidozo v makrofagih v pljučih, ker se je memantin kopičil v lizosomih.
English: Possible side effects
Bulgarian: Možni neželeni učinki
English: In order to reduce the risk of side effects this dose is achieved gradually by the following daily treatment scheme:
Bulgarian: Da bi zmanjšali nevarnost pojava neželenih učinkov, odmerek dosegate postopoma, po priporočilu sledeče
English: Driving and using machines
Bulgarian: in upravljanja strojev
English: The maximum daily dose is 20 mg per day.
Bulgarian: Največji dnevni odmerek je 20 mg na dan.
English: Infections and infestations
Bulgarian: Infekcijske in parazitske bolezni
English: Moderate to severe Alzheimer's disease usually causes impairment of driving performance and compromises the ability to use machinery.
Bulgarian: Zmerna do huda Alzheimerjeva bolezen je običajno vzrok za nesposobnost vožnje
English: week 1
Bulgarian: tedna dalje
English: None of these metabolites exhibit NMDA-antagonistic activity.
Bulgarian: Noben od teh presnovkov nima antagonističnega učinka na NMDA.
English: These events have been reported in patients treated with memantine.
Bulgarian: Pri bolnikih, zdravljenih z memantinom, so poročali o teh dogodkih.
English: Sandoz d.d Representative office Teл.
Bulgarian: Sandoz d.d Representative office
English: - This medicine has been prescribed for you only.
Bulgarian: - Zdravilo je bilo predpisano vam osebno in ga ne smete dajati drugim.
English: Distribution
Bulgarian: Porazdelitev
English: Respiratory, thoracic and mediastinal disorders
Bulgarian: Bolezni dihal, prsnega koša in mediastinalnega prostora
English: The brain contains so-called N-methyl-D-aspartate (NMDA)-receptors that are involved in transmitting nerve signals important in learning and memory.
Bulgarian: se nahajajo tako imenovani receptorji N-metil-D-aspartata (NMDA), ki sodelujejo v prenosu živčnih
English: - If you have any further questions, ask your doctor or pharmacist.
Bulgarian: - Če imate dodatna vprašanja, se posvetujte z zdravnikom ali
English: Tablet core: croscarmellose sodium, colloidal anhydrous silica, microcrystalline cellulose, magnesium stearate
Bulgarian: Jedro tablete: mikrokristalna celuloza, premrežen natrijev karmelozat, brezvoden koloidni silicijev dioksid in magnezijev stearat.
English: Cardiac failure
Bulgarian: Srčne bolezni
English: Memantine-treated patients showed a statistically significantly better effect than placebo-treated patients on the primary endpoints: Alzheimer's disease assessment scale (ADAS-cog) (p=0.003) and CIBIC-plus (p=0.004) at week 24 (last observation carried forward (LOCF)).
Bulgarian: statistično značilno boljši učinek kot pri bolnikih, ki so prejemali placebo pri primarnih ciljih študije: lestvica za ocenjevanje Alzheimerjeve bolezni (ADAS-cog- Alzheimer's disease assessment scale) (p=0,003) in CIBIC-plus (p=0,004) po 24 tednih (prenos zadnjega opažanja (LOCF-last observation carried forward)).
English: Memantine LEK is for oral use.
Bulgarian: Zdravilo Memantine LEK je namenjeno za peroralno uporabo.
English: Frequency
Bulgarian: Pogostnost
English: The recommended dose of Memantine LEK for adults and elderly patients is 20 mg once a day.
Bulgarian: Za odrasle in starejše je priporočeni odmerek zdravila Memantin LEK 20 mg enkrat dnevno.
English: Uncommon (may affect up to 1 in 100 people):
Bulgarian: Občasni (pojavijo se lahko pri največ 1 od 100 bolnikov):
English: 5.2 Pharmacokinetic properties
Bulgarian: 5.2 Farmakokinetične lastnosti
English: A pivotal monotherapy study of memantine in the treatment of mild to moderate Alzheimer's disease (MMSE total scores at baseline of 10 to 22) included 403 patients.
Bulgarian: Temeljna študija memantina v monoterapiji pri zdravljenju bolnikov z blago do zmerno Alzheimerjevo boleznijo (skupna ocena pri KPSS ob vključitvi 10 do 22 točk) je zajela 403 bolnike.
English: A. MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Bulgarian: ZA SPROŠČANJE SERIJ B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE C. DRUGI POGOJI IN ZAHTEVE DOVOLJENJA
English: France Sandoz
Bulgarian: Sandoz
English: When daily doses of 5 to 30 mg were administered, a mean cerebrospinal fluid (CSF)/serum ratio of 0.52 was calculated.
Bulgarian: Izračunali so, da je pri dnevnih odmerkih 5 do 30 mg razmerje med koncentracijo v cerebrospinalnem likvorju (CSL) in serumu 0,52.
English: Common (may affect up to 1 in 10 people):
Bulgarian: Pogosti (pojavijo se lahko pri največ 1 od 10 bolnikov):
English: 4.8 Undesirable effects
Bulgarian: Neželeni učinki
English: Iron oxide yellow (E 172)
Bulgarian: smukec rumen železov oksid (E 172)
English: - If you get any side effects, talk to your doctor or pharmacist.
Bulgarian: - Če opazite kateri koli neželeni učinek, se posvetujte z zdravnikom ali farmacevtom.
English: Film-coating: polyvinyl alcohol, titanium dioxide (E-171), talc, macrogol 3350, iron oxide yellow (E172) and iron oxide red (E-172)
Bulgarian: Filmska obloga: polivinilalkohol, makrogol 3350, titanov dioksid (E 171), smukec, rumen železov oksid (E 172) in rdeč železov oksid (E 172).
English: In man, about 80% of the circulating memantine-related material is present as the parent compound.
Bulgarian: Pri človeku je okoli 80 % memantina v obtoku v nespremenjeni obliki.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Bulgarian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovaje in izdaja zdravila je le
English: Immune system disorders
Bulgarian: Bolezni imunskega sistema
English: These factors include drastic changes in diet, e.g. from a carnivore to a vegetarian diet, or a massive ingestion of alkalising gastric buffers.
Bulgarian: Mednje spadajo izrazite spremembe v prehranjevanju, kot npr. prehod z običajne na vegetarijansko prehrano ali zaužitje večjih količin alkalnodelujočih antacidov.
English: What Memantine LEK looks like and contents of the pack Memantine LEK 10 mg film-coated tablets are presented as yellow, oval film-coated tablet scored in one side.
Bulgarian: Izgled zdravila Memantin LEK in vsebina pakiranja Memantin LEK 10 mg filmsko obložene tablete so rumene, ovalne, filmsko obložene tablete z razdelilno zarezo na eni strani.
English: Constipation Vomiting Pancreatitis2
Bulgarian: Neznana pankreatitis2
English: INFORMATION IN BRAILLE Memantine LEK 10 mg
Bulgarian: PODATKI V BRAILLOVI PISAVI Memantin LEK 10 mg
English: INFORMATION IN BRAILLE Memantine LEK 20 mg
Bulgarian: PODATKI V BRAILLOVI PISAVI Memantin LEK 20 mg
English: In the prospectively defined primary analysis statistical significance was not reached at the primary efficacy endpoint at week 24.
Bulgarian: tednu ni bilo statistično značilnih razlik pri primarnih ciljih študije.
English: Memantine LEK contains the active substance memantine hydrochloride.
Bulgarian: Zdravilo Memantine LEK vsebuje učinkovino memantinijev klorid.