FrancophonIA/ELRC3.0 huggingface dataset:
English: The active substance in Azilect, rasagiline, is a ‘monoamine oxidase-B inhibitor'.
Croatian: Djelatna tvar u lijeku Azilect, razagilin, je „inhibitor monoaminooksidaze B”.
English: Azilect can only be obtained with a prescription.
Croatian: Azilect se izdaje samo na liječnički recept.
English: The other two studies involved a total of 1,159 patients with later stage disease, where Azilect was added to the patients' existing treatment including levodopa.
Croatian: U ostalim dvama ispitivanjima sudjelovalo je 1159 bolesnika u kasnijoj fazi bolesti, a lijek Azilect dodan je postojećoj terapiji, koja je uključivala levodopu.
English: It was compared with placebo or entacapone (another medicine for Parkinson's disease).
Croatian: Lijek je uspoređen s placebom ili entakaponom (drugim lijekom koji se upotrebljava za liječenje Parkinsonove bolesti).
English: Why has Azilect been approved?
Croatian: Zašto je lijek Azilect odobren?
English: Azilect can be used either alone, or as an add-on to levodopa (another medicine used in Parkinson's disease) in patients who are having ‘fluctuations' towards the end of the period between levodopa doses.
Croatian: Azilect se može koristiti kao monoterapija ili kao dodatna terapija uz lijek levodopu (drugi lijek koji se koristi za liječenje Parkinsonove bolesti) u bolesnika s „fluktuacijama“ prilikom isteka doze lijeka levodope.
English: It must also not be used with pethidine (a painkiller).
Croatian: Također se ne smije uzimati zajedno s petidinom (lijek protiv bolova).
English: In the first study, two different doses of Azilect taken alone were compared with placebo (a dummy treatment) in 404 patients with early-stage disease.
Croatian: U prvom su ispitivanju dvije različite doze Azilecta koji se primjenjivao kao samostalna terapija uspoređene s placebom (prividno liječenje) u 404 bolesnika u ranoj fazi bolesti.
English: The CHMP decided that Azilect's benefits are greater than its risks and recommended that it be given marketing authorisation.
Croatian: Odbor za lijekove za humanu uporabu (CHMP) pri Agenciji odlučio je da koristi od lijeka Azilect nadmašuju s njim povezane rizike te je preporučio izdavanje odobrenja za stavljanje lijeka u promet.
English: What is Azilect?
Croatian: Što je Azilect?
English: Fluctuations are linked to a reduction in the effects of levodopa, when the patient experiences sudden switches between being ‘on' and able to move, and being ‘off' and immobile.
Croatian: Fluktuacije su povezane sa smanjenim učinkom lijeka levodope, kada bolesnik doživljava iznenadne izmjene dobrog stanja i mogućnosti kretanja te lošeg stanja i nemogućnosti kretanja.
English: In patients with Parkinson's disease, the cells that produce dopamine begin to die and the amount of dopamine in the brain decreases.
Croatian: Parkinsonovom bolešću stanice koje proizvode dopamin počinju odumirati i stoga se količina dopamina u mozgu smanjuje.
English: A similar decrease in time spent in the ‘off' state was seen in patients taking entacapone.
Croatian: Slično smanjenje u odnosu na vrijeme provedeno u lošem stanju primijećeno je u bolesnika koji su primali entakapon.
English: In both studies, patients adding Azilect spent an average of around one hour less in the ‘off' state than those adding placebo.
Croatian: U obama ispitivanjima bolesnici kojima je dodan lijek Azilect proveli su prosječno jedan sat manje u lošem stanju nego bolesnici koji su primali placebo.
English: For the full list of all side effects reported with Azilect, see the package leaflet.
Croatian: Potpuni popis svih nuspojava zabilježenih pri primjeni lijeka Azilect potražite u uputi o lijeku.
English: What benefit has Azilect shown during the studies?
Croatian: Koje su koristi lijeka Azilect utvrđene u ispitivanjima?
English: What is Azilect used for?
Croatian: Za što se Azilect koristi?
English: How is Azilect used?
Croatian: Kako se Azilect koristi?
English: How does Azilect work?
Croatian: Kako djeluje Azilect?
English: When used as an add-on to levodopa, 1 mg Azilect reduced the time in the ‘off' state more than placebo did.
Croatian: Doza od 1 mg Azilecta smanjila je vrijeme provedeno u lošem stanju više nego placebo kad je upotrijebljena kao dodatna terapija lijeku levodopi.
English: How has Azilect been studied?
Croatian: Kako je lijek Azilect ispitivan?
English: Further information on VeraSeal can be found on the Agency's website: ema.europa.eu/medicines/human/EPAR/veraseal
Croatian: Više informacija o lijeku VeraSeal dostupno je na internetskim stranicama Agencije: ema.europa.eu/medicines/human/EPAR/veraseal
English: What is VeraSeal and what is it used for?
Croatian: Što je VeraSeal i za što se koristi?
English: VeraSeal received a marketing authorisation valid throughout the EU on 10 November 2017.
Croatian: Lijek VeraSeal dobio je odobrenje za stavljanje u promet koje je na snazi u EU-u od 10. studenoga 2017.
English: Other information about VeraSeal
Croatian: Ostale informacije o lijeku VeraSeal
English: VeraSeal is used when standard surgery techniques do not work well enough.
Croatian: Lijek VeraSeal primjenjuje se kada standardne kirurške tehnike nisu dovoljno uspješne.
English: What measures are being taken to ensure the safe and effective use of VeraSeal?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka VeraSeal?
English: The European Medicines Agency therefore decided that VeraSeal's benefits are greater than its risks and recommended that it be approved for use in the EU.
Croatian: Stoga je Europska agencija za lijekove zaključila da koristi od lijeka VeraSeal nadmašuju s njim povezane rizike te je preporučila njegovo odobrenje za primjenu u EU-u.
English: It is available as two prefilled syringes in a syringe holder, one containing a solution of human fibrinogen (80 mg/ml), and the other containing a solution of human thrombin (500 international units/ml).
Croatian: Dostupan je u obliku dviju napunjenih štrcaljki u držaču štrcaljki, od kojih jedna sadržava otopinu ljudskog fibrinogena (80 mg/ml), a druga otopinu ljudskog trombina (500 međunarodnih jedinica/ml).
English: VeraSeal (human fibrinogen / human thrombin)
Croatian: VeraSeal (ljudski fibrinogen / ljudski trombin)
English: When the two active substances are mixed, thrombin cuts fibrinogen up into fibrin.
Croatian: Kada se dvije djelatne tvari pomiješaju, trombin razgrađuje fibrinogen u fibrin.
English: Side effects reported with VeraSeal are carefully evaluated and any necessary action taken to protect patients.
Croatian: Nuspojave prijavljene za lijek VeraSeal pažljivo se procjenjuju i poduzimaju se potrebne mjere za zaštitu bolesnika.
English: The amount of VeraSeal to be used depends on a number of factors, including the type of surgery, the size of the wound and the number of applications.
Croatian: Količina lijeka VeraSeal koju treba primijeniti ovisi o više čimbenika, uključujući vrstu kirurškog zahvata, veličinu rane i broj primjena.
English: Why is VeraSeal authorised in the EU?
Croatian: Zašto je lijek VeraSeal odobren u EU-u?
English: Although patients could develop antibodies against the medicine, which might reduce its effectiveness, this has not been seen in the studies.
Croatian: Iako bolesnici mogu razviti protutijela na lijek, što bi moglo smanjiti djelotvornost lijeka, to nije zabilježeno u ispitivanjima.
English: What are the risks associated with VeraSeal?
Croatian: Koji su rizici povezani s lijekom VeraSeal?
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of VeraSeal have been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka VeraSeal nalaze se u sažetku opisa svojstava i u uputi o lijeku.
English: As for all medicines obtained from blood, infections could be transmitted with the medicine; however, the medicine is manufactured using filtration and a process to inactivate viruses that minimise this risk.
Croatian: Kao i kod svih lijekova dobivenih iz krvi, moguć je prijenos infekcija primjenom lijeka; međutim, u proizvodnji lijeka koristi se filtriranje i postupak deaktivacije virusa kojima se taj rizik smanjuje.
English: An overview of VeraSeal and why it is authorised in the EU
Croatian: Pregled informacija o lijeku VeraSeal i zašto je odobren u EU-u
English: The active substances in VeraSeal, fibrinogen and thrombin, are substances present in human plasma (the liquid part of the blood), which are involved in the normal blood clotting process.
Croatian: Djelatne tvari lijeka VeraSeal, fibrinogen i trombin, tvari su koje se nalaze u ljudskoj plazmi (tekući dio krvi) i uključene su u normalan proces zgrušavanja krvi.
English: The most common side effects with VeraSeal (which may affect up to 1 in 10 people) are nausea (feeling sick), pruritus (itchiness) and procedural pain (pain from the surgery).
Croatian: Najčešće nuspojave lijeka VeraSeal (koje se mogu javiti u do 1 na 10 osoba) su mučnina (slabost), pruritus (svrbež) i bol uzrokovana postupkom (bol nakon kirurškog zahvata).
English: Rarely, VeraSeal may cause an allergic reaction which can be severe especially when the medicine is used repeatedly.
Croatian: U rijetkim slučajevima, lijek VeraSeal može izazvati alergijsku reakciju koja može biti teška, osobito kod opetovane primjene lijeka.
English: As for all medicines, data on the use of VeraSeal are continuously monitored.
Croatian: Kao i za sve lijekove, podatci o primjeni lijeka VeraSeal kontinuirano se prate.
English: The observed side effects were as expected with major surgeries or the patient's condition.
Croatian: Zabilježene nuspojave bile su u skladu s očekivanjima za veće kirurške zahvate ili stanje bolesnika.
English: VeraSeal has been shown to effectively stop bleeding during surgery, which can be expected to reduce blood loss, reduce time in the operating theatre and possibly shorten hospital stays.
Croatian: Utvrđeno je da je lijek VeraSeal djelotvoran u zaustavljanju krvarenja tijekom kirurškog zahvata, te se može očekivati smanjenje gubitka krvi, kraće vrijeme provedeno u operacijskoj dvorani i možda kraće bolničko liječenje.
English: Before use, the syringes are attached to a device supplied with the medicine that allows their contents to mix as they are dripped or sprayed on the wound.
Croatian: Štrcaljke se prije primjene pričvršćuju na uređaj dostavljen s lijekom koji omogućuje miješanje sadržaja štrcaljki prilikom primjene kapanjem ili raspršivanjem na ranu.
English: VeraSeal must not be used intravascularly (inside blood vessels) or to treat heavy bleeding of the arteries.
Croatian: Lijek VeraSeal ne smije se primjenjivati intravaskularno (unutar krvnih žila) niti za tretiranje obilnog arterijskog krvarenja.
English: VeraSeal should only be used by an experienced surgeon who has been trained in its use.
Croatian: Lijek VeraSeal trebaju primjenjivati samo kirurzi s iskustvom koji su uvježbani za primjenu tog lijeka.
English: Three main studies in 614 patients found that VeraSeal is effective at stopping bleeding within 4 minutes of applying it during surgery.
Croatian: U trima glavnim ispitivanjima koja su obuhvatila 614 bolesnika utvrđeno je da je lijek VeraSeal djelotvoran u zaustavljanju krvarenja unutar četiri minute od primjene lijeka tijekom kirurškog zahvata.
English: The fibrin then aggregates (sticks together) and forms a fibrin clot that helps the wound to heal, preventing bleeding.
Croatian: Fibrin se zatim skuplja (lijepi se) i oblikuje fibrinski ugrušak koji pomaže pri zacjeljivanju rane te sprječava krvarenje.
English: In rare cases, patients have developed antibodies to the proteins in VeraSeal, which could interfere with blood clotting.
Croatian: U rijetkim slučajevima bolesnici su razvili protutijela na bjelančevine u lijeku VeraSeal koji mogu ometati zgrušnjavanje krvi.
English: What benefits of VeraSeal have been shown in studies?
Croatian: Koje su koristi od lijeka VeraSeal utvrđene u ispitivanjima?
English: It contains the active substances human fibrinogen and human thrombin.
Croatian: Lijek sadrži djelatne tvari ljudski fibrinogen i ljudski trombin.
English: How does VeraSeal work?
Croatian: Kako djeluje lijek VeraSeal?
English: Finally, in a third study of soft tissue surgery, VeraSeal was as effective as Surgicel: 83% of the patients had no bleeding 4 minutes after treatment with VeraSeal (96 out of 116), compared with 78% of the patients after treatment with Surgicel (84 out of 108).
Croatian: Konačno, u trećem ispitivanju kirurških zahvata na mekom tkivu, lijek VeraSeal bio je jednako djelotvoran kao lijek Surgicel: četiri minute nakon primjene lijeka VeraSeal, krvarenje je prestalo u 83 % bolesnika (96 od 116), u usporedbi sa 78 % bolesnika (84 od 108) u kojih je krvarenje prestalo nakon primjene lijeka Surgicel.
English: In a second study of organ surgery, VeraSeal was as effective as another product Surgicel: 93% of the patients had no bleeding 4 minutes after treatment with VeraSeal (103 out of 111), while 81% of the patients had no bleeding with Surgicel (91 out of 113).
Croatian: U drugom ispitivanju kirurških zahvata na organima, lijek VeraSeal bio je jednako djelotvoran kao drugi lijek, Surgicel: četiri minute nakon primjene lijeka VeraSeal, krvarenje je prestalo u 93 % bolesnika (103 od 111), a nakon primjene lijeka Surgicel krvarenje je prestalo u 81 % bolesnika (91 od 113).
English: For the full list of all side effects and restrictions with VeraSeal, see the package leaflet.
Croatian: Potpuni popis svih nuspojava i ograničenja pri primjeni lijeka VeraSeal potražite u uputi o lijeku.
English: VeraSeal is a sealant (glue) used to stop bleeding during surgery or to support stitches during surgery on blood vessels.
Croatian: Lijek VeraSeal je tkivno ljepilo koje se primjenjuje za zaustavljanje krvarenja tijekom kirurškog zahvata ili za jačanje šavova tijekom kirurškog zahvata na krvnim žilama.
English: In one study of blood vessel surgery, VeraSeal worked better than manual compression, with 76% of patients having no bleeding 4 minutes after treatment with VeraSeal (83 out of 109), compared with 23% after manual compression (13 out of 57).
Croatian: bolesnika (83 od 109), u usporedbi s 23 % (13 od 57) bolesnika u kojih je primijenjena manualna kompresija.
English: Thromboembolic complications (blood clots) may occur if VeraSeal is accidentally injected into a blood vessel.
Croatian: U slučaju nehotičnog ubrizgavanja lijeka VeraSeal u krvnu žilu, moguće su tromboembolijske komplikacije (krvni ugrušci).
English: It spreads rapidly around the world.
Croatian: Brzo se širi cijelim svijetom.
English: Other special populations:
Croatian: Druge posebne populacije:
English: M = months.
Croatian: M = mjeseci.
English: The safety and efficacy of the vaccine in this population has not been established.
Croatian: Sigurnost i djelotvornost cjepiva u ovoj populaciji nisu još ustanovljene.
English: Södertälje Sweden
Croatian: Södertälje, Švedska
English: Read all of this leaflet carefully before the vaccine is given because it contains important information for you or your child.
Croatian: Pažljivo pročitajte cijelu uputu prije nego počnete uzimati ovaj lijek jer sadrži važne podatke za Vas i Vaše dijete.
English: After declaration in the EU of a pandemic and after implementation of the pandemic vaccine
Croatian: Nakon objave pandemije u EU i nakon implementacije pandemijskog cjepiva
English: A/Vietnam/1203/2004 (H5N1) strain (A/Vietnam/1203/2004, MEDI 0141000136)
Croatian: A/Vietnam/1203/2004 (H5N1) soj (A/Vietnam/1203/2004, MEDI 0141000136)
English: M = months Number of study participants for year 1 or year 2 primary efficacy analysis.
Croatian: M = mjeseci Broj sudionika ispitivanja u prvoj ili drugoj godini primarne analize djelotvornosti.
English: Two doses are recommended for all children and adolescents.
Croatian: Za svu djecu i adolescente se preporučuju dvije doze.
English: Adults aged 18 to 49 years
Croatian: Odrasli u dobi od 18 do 49 godina
English: • if you have a blood disorder or a cancer that affects the immune system.
Croatian: • ako imate poremećaj krvi ili rak koji utječu na imunološki sustav.
English: 1 dose (0.2 ml) contains:
Croatian: 1 doza (0,2 ml) sadrži:
English: No deaths resulted from these events, and none of the hospitalised children required mechanical ventilation or admission to an intensive care unit.
Croatian: Nijedan od ovih događaja nije rezultirao smrću i nijedno hospitalizirano dijete nije zahtijevalo mehaničku ventilaciju ili zaprimanje na odjel intenzivne skrbi.
English: Adults aged 22 to 54 years
Croatian: Odrasli u dobi od 22 do 54 godine
English: Subjects with 4-fold antibody rise (percentage)
Croatian: Ispitanici s 4-strukim povećanjem antitijela (postotak)
English: Pandemic flu is a type of influenza that happens at intervals that vary from less than 10 years to many decades.
Croatian: Pandemijska gripa je vrsta influence koja se pojavljuje u razdobljima koja variraju od manje od 10 godina do mnogo desetljeća.
English: Pack size of 10.
Croatian: Veličina pakiranja: 10.
English: At the time of approval of the next pandemic variation
Croatian: U trenutku odobrenja sljedeće izmjene pandemijskog soja
English: Influenza season
Croatian: Sezona influence
English: This is because of the risk of a very rare but serious disease (Reye's syndrome).
Croatian: To je zbog toga što postoji rizik od vrlo rijetke, ali ozbiljne bolesti (Reyev syndrome).
English: H1N1 pandemic LAIV vaccine in children aged 2 to 17 years
Croatian: Pandemijsko H1N1 LAIV cjepivo u djece u dobi od 2 do 17 godina
English: In accordance with Article 114 of Directive 2001/83/EC, the official batch release will be undertaken by a State laboratory or a laboratory designated for that purpose.
Croatian: Direktive 2001/83/EZ, službeno puštanje serije lijeka u promet preuzet će državni laboratorij ili laboratorij određen za tu svrhu.
English: • if you have been told by your doctor that you have a weakened immune system as a result of a disease, medicine, or other treatment.
Croatian: • ako Vam je Vaš liječnik rekao da imate oslabljen imunološki sustav kao posljedicu bolesti, uzimanja lijeka ili drugog oblika liječenja.
English: Date of first authorisation: 20 May 2016 Date of latest renewal: 4 April 2018
Croatian: Datum prvog odobrenja: 20. svibnja 2016.
English: • if you are already taking acetylsalicylic acid (a substance present in many medicines used to relieve pain and lower fever).
Croatian: • ako uzimate acetilsalicilatnu kiselinu (tvar prisutna u mnogim lijekovima koja se koristi za ublažavanje boli i snižavanje vrućice).
English: No data are available for individuals with significant clinical immunodeficiency.
Croatian: Nema dostupnih podataka za osobe sa značajnom kliničkom imunodeficijencijom.
English: Most hospitalisations were due to gastrointestinal and respiratory tract infections and occurred more than 6 weeks post vaccination.
Croatian: Većina hospitalizacija bila je uzrokovana infekcijom gastrointestinalnog i respiratornoga trakta i dogodila se više od 6 tjedana nakon cijepljenja.
English: However, in a pandemic situation, your doctor may recommend to give you the vaccine provided that appropriate medical treatement is immediately available in case of an allergic reaction.
Croatian: Međutim, u slučaju pandemije, Vaš liječnik može preporučiti da primite cjepivo, pod uvjetom da je odmah dostupno odgovarajuće liječenje u slučaju alergijske reakcije.
English: This medicine has been given “conditional approval”.
Croatian: Ovom lijeku izdano je „uvjetno odobrenje”.
English: All children will receive a second, follow-up dose after an interval of at least 4 weeks.
Croatian: Sva djeca će primiti drugu, naknadnu dozu nakon razdoblja od najmanje 4 tjedna.
English: If the vaccine has not been used after this 12-hour period, it should be discarded.
Croatian: Ako cjepivo nije primijenjeno nakon tog 12-satnog razdoblja, mora se zbrinuti u otpad.
English: HAI responses were not detected in any of the subjects after either the first or second dose of the vaccine.
Croatian: HAI odgovori nisu zabilježeni ni u jednog ispitanika ni nakon prve niti nakon druge doze cijepljenja.
English: Therefore, as some viruses are excreted in human milk, the vaccine should not be used during breastfeeding.
Croatian: Stoga, s obzirom da se neki virusi izlučuju u majčino mlijeko, cjepivo se ne bi trebalo primjenjivati tijekom dojenja.
English: • if you are in close contact with someone with a severely weakened immune system (for example, a bone marrow transplant patient needing isolation).
Croatian: • ako ste u bliskom kontaktu s nekim čiji je imunološki sustav jako oslabljen (na primjer, bolesnik kome je presađena koštana srž i koji treba izolaciju).
English: The maximum amount of ovalbumin is less than 0.024 micrograms per 0.2 ml dose (0.12 micrograms per ml).
Croatian: Maksimalna količina ovalbumina je manja od 0,024 mikrograma po dozi od 0,2 ml (0,12 mikrograma po ml).
English: Liverpool L24 9JW United Kingdom
Croatian: Liverpool L24 9JW, Ujedinjeno Kraljevstvo
English: No data are available for individuals with severe immunosuppression (see section 4.4).
Croatian: Nema dostupnih podataka za osobe s teškom imunosupresijom (vidjeti dio 4.4.).
English: Number of Vietnam inactivat ed vaccine doses
Croatian: Broj doza inaktiviranog cjepiva Vietnam
English: 56 Days after inactivated vaccine
Croatian: 56 dana nakon primjene inaktiviranog cjepiva
English: Children less than 12 months of age should not receive this vaccine because of the risk of side effects.
Croatian: Djeca mlađa od 12 mjeseci ne bi trebala primiti ovo cjepivo jer postoji rizik od nuspojava.
English: This leaflet was last revised in {MM/YYYY}
Croatian: Ova uputa je zadnji puta revidirana u {mjesec GGGG}.
English: The second dose should be administered after an interval of at least 4 weeks.
Croatian: Drugu dozu je potrebno primijeniti nakon razdoblja od najmanje 4 tjedna.
English: Serum samples were available from 7 subjects in Group 3 on Day 28 and from 18 subjects in Group 5 on Day 56.
Croatian: Uzorci seruma bili su dostupni od 7 ispitanika u Skupini 3 na 28. dan te od 18 ispitanika u Skupini 5 na 56. dan.
English: Data presented for clinical trial D153-P504 are for study participants who received two doses of study vaccine or placebo.
Croatian: Prikazani podaci iz kliničkog ispitivanja D153-P504 odnose se na sudionike ispitivanja koji su primili dvije doze ispitivanog cjepiva ili placeba.
English: Appropriate medical treatment and supervision should always be readily available in case of an anaphylactic event or hypersensitivity event following administration of the vaccine.
Croatian: Odgovarajuće liječenje i liječnički nadzor moraju uvijek biti lako dostupni u slučaju anafilaktičkog događaja ili događaja preosjetljivosti nakon primjene cjepiva.
English: The MAH should submit the final results of this study.
Croatian: Nositelj odobrenja treba predati konačne rezultate ovog ispitivanja.
English: Of these subjects, 319 received a second dose (256 subjects monovalent vaccine; 63 subjects placebo).
Croatian: Od ovih ispitanika, 319 je primilo drugu dozu (256 ispitanika primilo je monovalentno cjepivo; 63 ispitanika primilo je placebo).
English: It is used in children and adolescents 12 months to less than 18 years of age.
Croatian: Upotrebljava se u djece i adolescenata u dobi od 12 mjeseci do mlađih od 18 godina.
English: FFU per 0.2 ml dose
Croatian: FFU Po dozi od 0,2 ml
English: Immune response in patients with endogenous or iatrogenic immunosuppression may be insufficient.
Croatian: Imunološki odgovor u bolesnika s endogenom ili jatrogenom imunosupresijom može biti nedostatan.
English: • If you are pregnant, think you may be pregnant, or plan to become pregnant soon, tell your doctor, nurse or pharmacist before vaccination.
Croatian: • Ako ste trudni, mislite da biste mogli biti trudni, planirate uskoro imati dijete obavijestite svog liječnika, medicinsku sestru ili ljekarnika prije nego primite ovo cjepivo.
English: 28 Days after inactivated vaccine
Croatian: 28 dana nakon primjene inaktiviranog cjepiva