FrancophonIA/ELRC3.0 huggingface dataset:
English: Peak efavirenz plasma concentrations of 1.6-9.1 microM were attained by 5 hours following single oral doses of 100 mg to 1,600 mg administered to uninfected volunteers.
Danish: De højeste efavirenz-plasmakoncentrationer på 1,6 - 9,1 mikroM blev nået senest 5 timer efter orale enkeltdoser på 100 - 1.600 mg, der blev indgivet til ikke-inficerede frivillige.
English: Efavirenz has not been studied in controlled studies in patients with advanced HIV disease, namely with CD4 counts < 50 cells/mm3, or in PI or NNRTI experienced patients.
Danish: Efavirenz er ikke undersøgt i kontrollerede undersøgelser med patienter med fremskreden hivsygdom, det vil sige CD4 tal < 50 celler/mm3 eller med PI- eller NNRTI-erfarne patienter.
English: - Medicines that impact heart rhythm: Medicines used to treat heart rhythm problems: such as flecainide or metoprolol.
Danish: - Lægemidler med indvirkning på hjerterytmen: - Lægemidler til behandling af problemer med hjerterytmen: fx flecainid eller metoprolol.
English: Other medicines and Efavirenz Teva You must not take Efavirenz Teva with certain medicines.
Danish: Brug af anden medicin sammen med Efavirenz Teva Du må ikke tage Efavirenz Teva sammen med visse former for medicin.
English: Efavirenz is a NNRTI of HIV-1.
Danish: Virkningsmekanisme Efavirenz er en NNRTIer af hiv-1.
English: The potential for cross-resistance between efavirenz and PIs is low because of the different enzyme targets involved.
Danish: Potentialet for krydsresistens mellem efavirenz og PI´ere er lille på grund af de forskellige enzymmål, der er involverede.
English: (CYP3A4 induction) Co-administration of efavirenz with atorvastatin, pravastatin, or simvastatin did not affect efavirenz AUC or Cmax values.
Danish: (CYP3A4-induktion) Samtidig administration af efavirenz og atorvastatin, pravastatin eller simvastatin påvirkede ikke efivarenz' AUCeller Cmax-værdier.
English: Skin rash was considered treatment-related in 18% of patients treated with efavirenz.
Danish: Hududslæt blev betragtet som behandlingsrelateret hos 18% af de patienter, der blev behandlet med efavirenz.
English: Liver enzymes: Elevations of AST and ALT to greater than five times the upper limit of the normal range (ULN) were seen in 3% of 1,008 patients treated with 600 mg of efavirenz (5-8% after long-term treatment in study 006).
Danish: Leverenzymer: Der sås forhøjelser af ASAT og ALAT til mere end 5 gange den øvre grænse for normalområdet (ULN) hos 3% af 1.008 patienter behandlet med 600 mg efavirenz (5-8% efter langtidsbehandling i Undersøgelse 006).
English: (Decrease in itraconazole concentrations: CYP3A4 induction)
Danish: (fald i itraconazolkoncentrationen: CYP3A4-induktion)
English: Your doctor may consider giving you an alternative medicine or changing the dose of the protease inhibitors.
Danish: Lægen kan overveje at give dig anden medicin eller at ændre dosen af proteasehæmmere.
English: No effect (↔) equals a decrease in mean ratio estimate of ≤20% or increase in mean ratio estimate of administered with efavirenz.
Danish: Ingen effekt (↔) giver et fald i estimat af gennemsnits ratio på 20% eller en stigning i gennemsnits estimat på <25%
English: Teva Santé Tél: +33 155917800
Danish: Tél: +33 155917800
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON FOR BLISTER PACK CONTAINING OF <30><30x1><90><90 x 1> EFAVIRENZ TEVA 600 mg FILM-COATED TABLETS
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE ÆSKE TIL BLISTERPAKNING MED <30><30x1><90><90 x 1> EFAVIRENZ TEVA 600 mg FILMOVERTRUKNE TABLETTER
English: Elevations of GGT to greater than five times ULN were observed in 4% of all patients treated with 600 mg of efavirenz and 1.5-2% of patients treated with control regimens (7% of efavirenz-treated patients and 3% of control-treated patients after long-term treatment).
Danish: Der sås forhøjelser af - GGT til mere end fem gange ULN hos 4% af alle patienter behandlet med 600 mg efavirenz og hos 1,5-2% af patienterne behandlet med kontrolregimerne (7% af de efavirenzbehandlede patienter og 3% patienter i kontrolgruppen efter langtidsbehandling).
English: Long-term results at 168 weeks of study 006 (160 patients completed study on treatment with EFV+IDV, 196 patients with EFV+ZDV+3TC and 127 patients with IDV+ZDV+3TC, respectively), suggest durability of response in terms of proportions of patients with HIV-RNA < 400 copies/ml, HIV-RNA < 50 copies/ml and in terms of mean change from baseline CD4 cell count.
Danish: Langtidsresultater efter 168 uger i Undersøgelse 006 (160 patienter fuldførte undersøgelsen med EFV+IDV, 196 med EFV+ZDV+3TC og 127 patienter med IDV+ZDV+3TC) tyder på varigt respons med hensyn til mængden af patienter med hiv RNA < 400 kopier/ml, hiv RNA < 50 kopier/ml og med hensyn til middelændring fra baseline af CD4 celletal.
English: Efavirenz Teva taken in combination with other antiretroviral medicines reduces the amount of the virus in the blood.
Danish: Efavirenz Teva taget sammen med anden antiretroviral behandling reducerer mængden af virus i blodet.
English: Multipack: 90 (3 packs of 30 x 1) film-coated tablets
Danish: Multipack: 90 (3 pakninger à 30 x 1) filmovertrukne tabletter
English: Compounds or herbal preparations (for example Ginkgo biloba extracts and St. John's wort) which induce these enzymes may give rise to decreased plasma concentrations of efavirenz.
Danish: Lægemiddelstoffer eller naturlægemidler (f.eks. Ginkgo biloba og perikon, der inducerer disse enzymer, kan medføre nedsat plasmakoncentration af efavirenz.
English: A. MANUFACTURER RESPONSIBLE FOR BATCH RELEASE
Danish: A. FREMSTILLER(E)/ANSVARLIG(E) FOR BATCHFRIGIVELSE
English: - Methadone (a medicine used to treat opiate addiction): your doctor may recommend an alternative treatment.
Danish: - Methadon (medicin til behandling af opioidmisbrug): Lægen vil måske tilråde en anden behandling.
English: - Immunosuppressants such as cyclosporine, sirolimus, or tacrolimus (medicines used to prevent organ transplant rejection): when you start or stop taking Efavirenz Teva, your doctor will closely monitor your plasma levels of the immunosuppressant and may need to adjust its dose.
Danish: - Immunsuppressive lægemidler såsom ciclosporin, sirolimus eller tacrolimus (medicin til at forhindre afstødelse af organer efter transplantation): når du starter eller stopper med at tage Efavirenz Teva vil lægen kontrollere indholdet af det immunsuppressive lægemiddel i blodet, og det kan være nødvendigt at justere dosis.
English: Experience with efavirenz in patients who discontinued other antiretroviral agents of the NNRTI class is limited.
Danish: Erfaring med efavirenz hos patienter, som er ophørt med andre antiretrovirale lægemidler af NNRTI-gruppen, er begrænset.
English: In HIV infected patients with severe immune deficiency at the time of initiation of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Danish: Hos hiv-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske infektioner.
English: Liver enzymes in hepatitis B or C co-infected patients In the long-term data set from study 006, 137 patients treated with efavirenz-containing regimens (median duration of therapy, 68 weeks) and 84 treated with a control regimen (median duration, 56 weeks) were seropositive at screening for hepatitis B (surface antigen positive) and/or C (hepatitis C antibody positive).
Danish: Leverenzymer hos patienter, der er co-inficeret med hepatitis B eller C I langtidsdata fra undersøgelse 006 var 137 patienter i regimer, der indeholder efavirenz (median behandlingsvarighed 68 uger), og 84 patienter i kontrolregimer (median behandlingsvarighed 56 uger) seropositive ved screening for hepatitis B (overfladeantigen-positive) og/eller C (hepatitis C antistof positive).
English: - The other ingredients are cellulose microcrystalline, hydroxypropylcellulose, sodium laurilsulfate, sodium starch glycolate (Type A), poloxamer 407 and magnesium stearate in the core.
Danish: - De øvrige indholdsstoffer er mikrokrystallinsk cellulose, hydroxypropylcellulose, natriumlaurilsulfat, natriumstivelsesglycolat (Type A), poloxamer 407 og magnesiumstearat i tabletkernen.
English: If the co-administration of atazanavir with an NNRTI is required, an increase in the dose of both atazanavir and ritonavir to 400 mg and 200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
Danish: Hvis samtidig administration af atazanavir og et NNRTI er nødvendig, bør det overvejes at øge dosis for både atazanavir og ritonavir til henholdsvis 400 mg og 200 mg sammen med efavirenz med tæt klinisk monitorering.
English: - Efavirenz Teva film-coated tablets are not suitable for children weighing less than 40 kg. - The dose for children weighing 40 kg or more is 600 mg once daily.
Danish: - Efavirenz Teva filmovertrukne tabletter er ikke egnet til børn, der vejer mindre end 40 kg. - Dosis til børn, der vejer 40 kg eller mere er 600 mg 1 gang dagligt.
English: Isolated elevations of GGT in patients receiving efavirenz may reflect enzyme induction.
Danish: Isolerede forhøjelser af GGT hos patienter som får efavirenz kan vise enzyminduktion.
English: c S.E.M., standard error of the mean.
Danish: c S.E.M., standard afvigelse på middelværdi.
English: Cellulose, microcrystalline Hydroxypropylcellulose Sodium laurilsulfate Sodium starch glycolate (Type A) Poloxamer 407
Danish: Mikrokrystallinsk cellulose Hydroxypropylcellulose Natriumlaurilsulfat Natriumstivelsesglykolat (Type A) Poloxamer 407
English: Contact your doctor or pharmacist for advice.
Danish: Spørg din læge eller apotekspersonlet om råd.
English: - Medicines used to treat fungal infections (antifungals):
Danish: - Medicin til behandling af svampeinfektioner (antimykotikum):
English: Total active HMG CoA reductase inhibitors:
Danish: Totalt aktive HMG Co-A reduktasehæmmere:
English: Contents of the pack and other information What Efavirenz Teva contains
Danish: Pakningsstørrelser og yderligere oplysninger Efavirenz Teva indeholder
English: Barrier contraception should always be used in combination with other methods of contraception (for example, oral or other hormonal contraceptives, see section 4.5).
Danish: Barrierekontraception bør altid anvendes sammen med andre kontraceptiva (f.eks. orale eller andre hormonelle kontraceptiva, se pkt.
English: Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Danish: Lægemidlet må kun udleveres efter begrænset recept (Jf. bilag I: Produktresumé, pkt.
English: HORMONAL CONTRACEPTIVES Oral:
Danish: HORMONELLE KONTRACEPTIVA
English: d S.E.M., standard error of the mean.
Danish: d S.E.M., standard afvigelse på middelværdi.
English: Common Abdominal pain, diarrhoea, nausea, vomiting Uncommon Pancreatitis
Danish: Almindelig Abdominale smerter, diarré, kvalme, opkastning Ikke almindelig
English: - severe depression - suicidal ideation - non-fatal suicide attempts - aggressive behaviour - paranoid reactions - manic reactions
Danish: - Aggressiv adfærd - Paranoide reaktioner - Maniske reaktioner
English: (Inhibition of CYP-mediated oxidative metabolism) When efavirenz was given with ritonavir 500 mg or 600 mg twice daily, the combination was not well tolerated (for example, dizziness, nausea, paraesthesia and elevated liver enzymes occurred).
Danish: Når efavirenz blev givet sammen med ritonavir 500 mg eller 600 mg to gange dagligt, var kombinationen ikke veltolereret (bl.a. forekom svimmelhed, kvalme, paræstesier og forhøjede leverenzymer).
English: - Sertraline (a medicine used to treat depression): your doctor may need to change your dose of sertraline.
Danish: - Sertralin (medicin til behandling af depression): Lægen vil måske vil være nødt til at ændre din sertralindosis.
English: The long-term safety profile of efavirenz-containing regimens was evaluated in a controlled trial (006) in which patients received efavirenz + zidovudine + lamivudine (n = 412, median duration 180 weeks), efavirenz + indinavir (n = 415, median duration 102 weeks), or indinavir + zidovudine + lamivudine (n = 401, median duration 76 weeks).
Danish: Langtidssikkerhedsprofilen for regimer indeholdende efavirenz blev evalueret i en kontrolleret undersøgelse (006), hvor patienter behandledes med enten efavirenz + zidovudin + lamivudin (n = 412, medianvarighed 180 uger), eller efavirenz + indinavir (n = 415, medianvarighed 102 uger) eller indinavir + zidovudin + lamivudin (n = 401, medianvarighed 76 uger).
English: - You must remain under the care of your doctor while taking Efavirenz Teva.
Danish: - du skal fortsat tilses af din læge, mens du tager Efavirenz Teva.
English: Mean AUC(0-24) µM·h
Danish: AUC(0-24)
English: Women of childbearing potential should undergo pregnancy testing before initiation of efavirenz.
Danish: Kvinder i den fertile alder skal have foretaget graviditetstest, før behandling med efavirenz initieres.
English: Efavirenz Teva may interact with other medicines, including herbal preparations such as Ginkgo biloba extracts.
Danish: Efavirenz Teva kan påvirke eller påvirkes af anden medicin, herunder naturlægemidler som Ginkgo biloba.
English: Effects on drug levels Mean percent change in AUC, Cmax, Cmin with confidence intervals if availablea
Danish: Indvirkning på lægemiddelkoncentrationen, gennemsnitlig ændring (%) i AUC, Cmax, Cmin med konfidensintervaller hvis muligta
English: voriconazole.
Danish: voriconazol.
English: Common (affects 1 to 10 users in 100)
Danish: Almindelige (berører 1 til 10 ud af 100 brugere)
English: Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicinal product.
Danish: Bør ikke anvendes til patienter med hereditær galactoseintolerans, total lactasemangel eller glucose/galactose malabsorption.
English: - Ginkgo biloba extracts (a herbal preparation)
Danish: - Ginkgo biloba (et naturlægemiddel).
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS EFAVIRENZ TEVA 600 mg FILM-COATED TABLET: BLISTER FOIL LABEL
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS EFAVIRENZ TEVA 600 mg FILMOVERTRUKKET TABLET: ETIKET PÅ BLISTERFOLIE
English: - Each Efavirenz Teva film-coated tablet contains 600 mg of the active substance efavirenz.
Danish: - Hver Efavirenz Teva filmovertrukken tablet indeholder 600 mg af det aktive stof efavirenz.
English: AUC: ↑ 7% (↑ 1 to ↑ 14) Cmax: ↑ 16% (↑ 2 to ↑ 32) These changes are not considered clinically significant.
Danish: AUC: ↑ 7% (↑ 1 til ↑ 14) Cmax: ↑ 16% (↑ 2 til ↑ 32) Disse forandringer anses ikke for at være klinisk signifikante.
English: AUC: ↑ 11% (↑ 5 to ↑ 18) Cmax: ↑ 16% (↑ 6 to ↑ 26) Cmin: ↑ 13% (↑ 1 to ↑ 26) (CYP3A4 induction) The increase in efavirenz pharmacokinetic parameters is not considered clinically significant.
Danish: AUC: ↑ 11% (↑ 5 til ↑ 18) Cmax: ↑ 16% (↑ 6 til ↑ 26) Cmin: ↑ 13% (↑ 1 til ↑ 26) (CYP3A4-induktion) Stigningen i efavirenz' farmakokinetiske parametre anses ikke for at være klinisk signifikant.
English: Rare (affects 1 to 10 users in 10,000)
Danish: Sjældne (berører 1 til 10 ud af 10.000 brugere)
English: Among co-infected patients, 3% of those treated with efavirenz and 2% in the control arm discontinued because of liver disorders (see section 4.4).
Danish: Blandt de co-inficerede patienter stoppede 3% i efavirenz-gruppen og 2% i kontrolgruppen på grund af leversygdom (se pkt.
English: Morning AUC: ↑ 18% (↑ 6 to ↑ 33) Evening AUC: ↔
Danish: AUC morgen: ↑ 18% (↑ 6 til ↑ 33) AUC aften: ↔
English: Reported rates of recurrent rash following a switch from nevirapine to efavirenz therapy, primarily based on retrospective cohort data from published literature, range from 13 to 18%, comparable to the rate observed in patients treated with efavirenz in clinical studies (see section 4.4).
Danish: Hyppigheden af tilbagevendende udslæt efter skift fra behandling med nevirapin til efavirenz, varierer fra 13 til 18% (primært baseret på retrospektive kohortedata fra publiceret litteratur), hvilket svarer til hyppigheden hos patienter, der er blevet behandlet med efavirenz i kliniske undersøgelser (se pkt.
English: Efavirenz has not been adequately studied in patients with advanced HIV disease, namely in patients with CD4 counts < 50 cells/mm3, or after failure of protease inhibitor (PI)-containing regimens.
Danish: Efavirenz er ikke tilstrækkeligt undersøgt hos patienter med fremskreden hiv-sygdom, det vil sige patienter med CD4 tal < 50 celler/mm3, eller efter svigtende effekt af proteasehæmmerregimer (PI).
English: The most notable unwanted effects reported with efavirenz in combination with other anti-HIV medicines are skin rash and nervous system symptoms.
Danish: De mest fremtrædende bivirkninger, der er rapporteret i forbindelse med efavirenz i kombination med andre anti-hiv-lægemidler, er udslæt og symptomer fra nervesystemet.
English: Mild-to-moderate rash has been reported in clinical studies with efavirenz and usually resolves with continued therapy.
Danish: Der er rapporteret mildt til moderat udslæt i kliniske undersøgelser med efavirenz, og dette forsvinder sædvanligvis ved fortsat behandling.
English: < 400 copies/ml (95% C.I.b)
Danish: < 400 kopier/ml (95% C.I.b)
English: Efavirenz Teva contains sodium
Danish: Efavirenz Teva indeholder natrium
English: Do not take Efavirenz Teva).
Danish: 2 Tag ikke Efavirenz Teva).
English: Efavirenz Teva may reduce the amount of voriconazole in your blood and voriconazole may increase the amount of efavirenz in your blood.
Danish: Efavirenz Teva kan mindske mængden af voriconazol i blodet, og voriconazol kan øge mængden af efavirenz i blodet.
English: Thirty-seven patients 3 months to 6 years of age (median 0.7 years) were treated with efavirenz.
Danish: 37 patienter, mellem 3 måneder og 6 år (gennemsnit 0,7 år) blev behandlet med efavirenz.
English: concentrations for at least 2 weeks (until stable concentrations are reached) is recommended when starting or stopping treatment with efavirenz.
Danish: Tæt monitorering af de immunsuppressive koncentrationer anbefales i mindst 2 uger (indtil stabil koncentration er nået), når
English: What you need to know before you take Efavirenz Teva Do NOT take Efavirenz Teva
Danish: Det skal du vide, før du begynder at tage Efavirenz Teva Tag ikke Efavirenz Teva
English: (CYP3A4 induction) Rash developed in 46% of uninfected volunteers receiving efavirenz and clarithromycin.
Danish: Udslæt forekom hos 46% af de ikke-inficerede frivillige, der fik efavirenz og clarithromycin.
English: Each film-coated tablet contains 600 mg efavirenz.
Danish: Hver filmovertrukken tablet indeholder 600 mg efavirenz.
English: Uncommon Tinnitus†, vertigo Vascular disorders
Danish: Tinnitus†, vertigo Vaskulære sygdomme Ikke almindelig
English: <50 copies/ml (95% C.I.b)
Danish: < 50 kopier/ml (95% C.I.b)
English: Grapefruit juice should be avoided when taking Efavirenz Teva.
Danish: Undlad at drikke grapefrugtjuice, når du tager Efavirenz Teva.
English: (hallucinations), mania (mental condition characterised by episodes of overactivity, elation or irritability), paranoia, suicidal thoughts, catatonia (condition in which the patient is rendered motionless and speechless for a period) - whistling, ringing or other persistent noise in the ears - tremor (shaking) - flushing
Danish: opstemthed eller irritabilitet), paranoia, selvmordstanker, katatoni (tilstand hvor patienten kan være ubevægelig og stum i en periode) - Fløjten, ringen eller anden vedvarende støj i ørerne - Skælven (tremor) - Rødmen
English: In order to improve the tolerability of nervous system adverse reactions, bedtime dosing is recommended (see section 4.8).
Danish: For at forbedre tolerabiliteten af bivirkninger fra nervesystemet anbefales dosering ved sengetid (se pkt.
English: Severe rash occurred in less than 1% of patients treated with efavirenz, and 1.7% discontinued therapy because of rash.
Danish: Svært udslæt optrådte hos færre end 1% af de efavirenzbehandlede patienter, og 1,7% ophørte med behandlingen på grund af udslæt.
English: - Hormonal contraceptive, such as birth control pills, an injected contraceptive (for example, Depo-Provera), or a contraceptive implant (for example, Implanon): you must also use a reliable barrier method of contraception (see Pregnancy, breast-feeding and fertility).
Danish: - Hormonel kontrakonception, såsom p-piller, kontraception som injektion (f.eks. DepoProvera) eller et kontraceptivt implantat (f.eks. Implanon): du skal også bruge en pålidelig kontraceptiv barrieremetode (se Graviditet, amning og fertilitet), da Efavirenz Teva kan bevirke, at virkningen af hormonel kontraception nedsættes.
English: Effects on drug levels Mean percent change in AUC, Cmax, Cmin with confidence intervals if availablea (mechanism)
Danish: Indvirkning på lægemiddelkoncentrationen, gennemsnitlig ændring (%) i AUC, Cmax, Cmin med konfidensintervaller hvis muligta (mekanisme)
English: One hundred two patients 3 months to 16 years of age (median 5.7 years) were treated with efavirenz.
Danish: 102 patienter, mellem 3 måneder og 16 år (gennemsnit 5,7 år) blev behandlet med efavirenz.
English: If efavirenz is co-administered with rifampicin to patients weighing 50 kg or more, an increase in the dose of efavirenz to 800 mg/day may be considered (see section 4.5).
Danish: Hvis efavirenz administreres sammen med rifampicin til voksne, der vejer 50 kg eller derover, kan det overvejes at øge dosis af efavirenz til 800 mg/dag (se pkt.
English: Voriconazole: AUC: ↓ 77% Cmax: ↓ 61%
Danish: Voriconazol: AUC: ↓ 77% Cmax: ↓ 61%
English: - Bupropion (a medicine used to treat depression or to help you stop smoking): your doctor may need to change your dose of bupropion.
Danish: - Bupropion (medicin mod depression eller til rygeafvænning): Lægen vil måske være nødt til at ændre din bupropiondosis.
English: - Diltiazem or similar medicines (called calcium channel blockers which are medicines typically used for high blood pressure or heart problems): when you start taking Efavirenz
Danish: - Diltiazem eller lignende medicin (kaldet calciumantagonister, som er lægemidler, der typisk anvendes til behandling af højt blodtryk eller hjerteproblemer): når du starter med at tage Efavirenz Teva kan lægen være nødt til at justere din dosis af calciumkanalblokker.
English: (CYP3A induction by efavirenz)
Danish: (CYP3A induktion af efavirenz)
English: (500/125 mg twice daily/ 600 mg once daily)
Danish: (500/125 mg to gange dagligt/600 mg én gang dagligt)
English: Serious birth defects have been seen in unborn animals and in the babies of women treated with efavirenz or a combination medicine containing efavirenz, emtricitabine and tenofovir during pregnancy.
Danish: Der er set alvorlige misdannelser hos ufødte dyr og hos spædbørn, hvis mødre er blevet behandlet med efavirenz under graviditeten.
English: Lopinavir concentrations: ↓ 30-40%
Danish: Lopinavirkoncentrationer: ↓ 30
English: imidazole and triazole antifungal agents, - certain non-sedating antihistamines (terfenadine, astemizole), - cisapride, - flecainide, - certain antimalarials, - methadone.
Danish: - visse non-sederende antihistaminer (terfenadin, astemizol) - cisaprid - flecainid - visse malariamidler - methadon.
English: When efavirenz is co-administered with voriconazole, the voriconazole maintenance dose must be increased to 400 mg twice daily and the efavirenz dose must be reduced by 50%, i.e. to 300 mg once daily.
Danish: Når efavirenz administreres sammen med voriconazol, bør vedligeholdelsesdosis for voriconazol øges til 400 mg to gange dagligt, og efavirenzdosis skal reduceres med 50%, dvs. 300 mg én gang dagligt.
English: You should not breast-feed your baby if you are taking Efavirenz Teva.
Danish: Du må ikke amme dit barn, hvis du tager Efavirenz Teva.
English: It is recommended that efavirenz be taken on an empty stomach.
Danish: Det anbefales at tage efavirenz på tom mave.