FrancophonIA/ELRC3.0 huggingface dataset:
English: ANTICONVULSANTS Carbamazepine/Efavirenz (400 mg once daily/600 mg once daily)
Croatian: ANTIKONVULZIVI karbamazepin/efavirenz (400 mg jedanput na dan/600 mg jedanput na dan)
English: Co-administration of simeprevir with efavirenz is not recommended.
Croatian: Istodobna primjena simeprevira s efavirenzom se ne preporučuje.
English: - Medicines used to treat depression such as imipramine, amitriptyline or clomipramine - Antibiotics, including the following types: macrolides, fluoroquinolones or imidazole.
Croatian: lijekovi koji utječu na srčani ritam: - lijekovi koji se koriste za liječenje problema srčanog ritma: kao što su flekainid ili metoprolol. - lijekovi koji se koriste za liječenje depresije kao što su imipramin, amitriptilin ili klomipramin. - antibiotici, uključujući sljedeće tipove: makrolidi, fluorokinoloni ili imidazol.
English: AUC: ↓ 36% (↓ 32 to ↓ 40)
Croatian: AUC: ↓ 36% (↓ 32 do
English: Nervous system symptoms usually begin during the first one or two days of therapy and generally resolve after the first 2 - 4 weeks.
Croatian: Simptomi živčanog sustava obično se počinju javljati prvog ili drugog dana liječenja i uglavnom nestaju nakon 2 do 4 tjedna.
English: SUSTIVA 100 mg hard capsules
Croatian: SUSTIVA 100 mg tvrde kapsule
English: EXPIRY DATE EXP
Croatian: EXP
English: AUC: ↓ 75% (↓ 59 to ↓ 84)
Croatian: AUC: ↓ 75% (↓ 59 do
English: INFORMATION IN BRAILLE SUSTIVA 200 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU SUSTIVA 200 mg
English: The median increase from baseline in CD4+ count at 48 weeks was 215 cells/mm and the median increase in CD4+ percentage was 6%.
Croatian: Medijan porasta broja CD4+ stanica od početne vrijednosti do 48. tjedna iznosio je 215 stanica/mm3, a medijan porasta postotka CD4+ stanica iznosio je 6%.
English: ANNEX II
Croatian: Dublin 15
English: SUSTIVA 100 mg hard capsules can be taken by children and adolescents 3 months of age and older and weighing at least 3.5 kg who are able to swallow the capsules.
Croatian: SUSTIVA 100 mg tvrde kapsule mogu uzimati djeca u dobi od 3 mjeseca i starija te adolescenti tjelesne mase ne manje od 3,5 kg, koja mogu progutati kapsule.
English: SUSTIVA 50 mg hard capsules can be taken by children and adolescents 3 months of age and older and weighing at least 3.5 kg who are able to swallow the capsules.
Croatian: SUSTIVA 50 mg tvrde kapsule mogu uzimati djeca u dobi od 3 mjeseca i starija te adolescenti tjelesne mase ne manje od 3,5 kg, koja mogu progutati kapsule.
English: AUC: ↓ 34% (↓ 21 to ↓ 41)
Croatian: AUC: ↓ 34% (↓ 21 do
English: SUSTIVA 50 mg hard capsules efavirenz
Croatian: SUSTIVA 50 mg tvrde kapsule efavirenz
English: The pharmacokinetics of efavirenz have not been studied in patients with renal insufficiency; however, less than 1% of an efavirenz dose is excreted unchanged in the urine, so the impact of renal impairment on efavirenz elimination should be minimal (see section 4.2).
Croatian: S obzirom da se manje od 1% doze efavirenza izlučuje mokraćom u nepromijenjenom obliku, utjecaj oštećenja bubrega na eliminaciju efavirenza trebao bi biti minimalan (vidjeti dio 4.2).
English: Efavirenz was not mutagenic or clastogenic in conventional genotoxicity assays.
Croatian: Uobičajeni testovi genotoksičnosti nisu pokazali mutagene niti klastogene učinke efavirenza.
English: Coadministration of sofosbuvir/velpatasvir with efavirenz is not recommended (see section 4.5).
Croatian: Istodobna primjena sofosbuvira/velpatasvira s efavirenzom se ne preporučuje (vidjeti dio 4.5).
English: No dose adjustment is necessary for either medicinal product.
Croatian: Nije potrebno prilagođavati dozu niti jednog lijeka.
English: SUSTIVA can reduce the amount of statins in your blood.
Croatian: SUSTIVA može smanjiti koncentraciju statina u krvi.
English: Marketing Authorisation Holder Bristol-Myers Squibb Pharma EEIG Plaza 254
Croatian: Nositelj odobrenja za stavljanje lijeka u promet Bristol-Myers Squibb Pharma EEIG Plaza 254
English: Rifampicin/Efavirenz (600 mg once daily/600 mg once daily)
Croatian: rifampicin/efavirenz (600 mg jedanput na dan/600 mg jedanput na dan)
English: Psychiatric adverse reactions have been reported in patients treated with efavirenz.
Croatian: U bolesnika liječenih efavirenzom prijavljene su psihijatrijske nuspojave.
English: Refer to the prescribing information for velpatasvir/sofosbuvir/ voxilaprevir for more information.
Croatian: Za više informacija pogledati podatke o propisivanju lijekova velpatasvir/sofosbuvir/voksilaprevir.
English: OUTER CARTON AND LABEL TEXT FOR BOTTLE PACK
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM I UNUTARNJEM PAKIRANJU TEKST NA KUTIJI I NALJEPNICI BOČICE
English: AUC: ↓ 37% (↓ 14 to ↓ 55)
Croatian: AUC: ↓ 37% (↓ 14 do
English: ANTIANXIETY AGENTS Lorazepam/Efavirenz (2 mg single dose/600 mg once daily)
Croatian: ANKSIOLITICI lorazepam/efavirenz (2 mg u jednokratnoj dozi/600 mg jedanput na dan)
English: Refer to the prescribing information for sofosbuvir/velpatasvir for more information.
Croatian: Za više informacija pogledati podatke o propisivanju lijekova sofosbuvir/velpatasvir.
English: Efavirenz: AUC: ↑ 44%
Croatian: AUC: ↑ 44%
English: Bottle: 30 film-coated tablets
Croatian: 30 filmom obloženih tableta Blister:
English: Bristol-Myers Squibb GmbH & CO. KGaA Tel: +49 89 121 42-0
Croatian: KGaA Tel: +49 89 121 42-0
English: AUC: ↑ 11% (↑ 5 to ↑ 18)
Croatian: AUC: ↑ 34% (↑ 18 do
English: Coadministration of glecaprevir/pibrentasvir with efavirenz is not recommended (see section 4.5).
Croatian: Istodobna primjena glekaprevira/pibrentasvira s efavirenzom se ne preporučuje (vidjeti dio 4.5).
English: Each hard capsule contains 200 mg of efavirenz.
Croatian: Jedna tvrda kapsula sadrži 200 mg efavirenza.
English: SUSTIVA 100 mg hard capsules efavirenz
Croatian: SUSTIVA 100 mg tvrde kapsule efavirenz
English: Nelfinavir/Efavirenz (750 mg q8h/600 mg once daily)
Croatian: nelfinavir/efavirenz (750 mg svakih 8h/600 mg jedanput na dan)
English: Cmin: ↓ 35% (↓ 24 to ↓ 44) Efavirenz:
Croatian: Cmax: ↓ 20% (↓ 15 do ↓ 24) Cmin: ↓ 35% (↓ 24 do ↓ 44) efavirenz:
English: Each hard capsule contains 100 mg of efavirenz.
Croatian: Jedna tvrda kapsula sadrži 100 mg efavirenza.
English: Antimycobacterials Rifabutin/Efavirenz (300 mg once daily/600 mg once daily)
Croatian: Antimikobakterijski lijekovi rifabutin/efavirenz (300 mg jedanput na dan/600 mg jedanput na dan)
English: Ritonavir/Efavirenz (500 mg twice daily/600 mg once daily)
Croatian: ritonavir/efavirenz (500 mg dvaput na dan/600 mg jedanput na dan)
English: Cmin: ↓ 82% (↓ 79 to ↓ 85) Levonorgestrel (active metabolite): AUC: ↓ 83% (↓ 79 to ↓ 87)
Croatian: Cmax: ↓ 46% (↓ 39 do ↓ 52) Cmin: ↓ 82% (↓ 79 do ↓ 85) levonorgestrel (aktivni metabolit):
English: NAME OF THE MEDICINAL PRODUCT SUSTIVA 600 mg film-coated tablets efavirenz
Croatian: NAZIV LIJEKA SUSTIVA 600 mg filmom obložene tablete efavirenz
English: Ritonavir:
Croatian: atovakvon:
English: Cmax: ↑ 38%
Croatian: Cmax: ↑ 38% vorikonazol:
English: AUC: ↓ 60% (↓ 52 to ↓ 68)
Croatian: AUC: ↓ 60% (↓ 52 do
English: Hepatic failure
Croatian: Insuficijencija bubrega
English: Resistant virus emerges rapidly when efavirenz is administered as monotherapy.
Croatian: Monoterapijska primjena efavirenza brzo dovodi do nastanka rezistentnog soja virusa.
English: The pharmacokinetics of efavirenz have not been studied in patients with renal insufficiency; however, less than 1% of an efavirenz dose is excreted unchanged in the urine, so the impact of renal impairment on efavirenz elimination should be minimal (see section 4.4).
Croatian: No s obzirom da se manje od 1% efavirenza izlučuje mokraćom u nepromijenjenom obliku, utjecaj oštećenja bubrega na eliminaciju efavirenza trebao bi biti minimalan (vidjeti dio 4.4).
English: Each hard capsule contains 50 mg of efavirenz.
Croatian: Jedna tvrda kapsula sadrži 50 mg efavirenza.
English: Posaconazole/Efavirenz --/400 mg once daily
Croatian: posakonazol/efavirenz --/400 mg jedanput na dan posakonazol:
English: Each hard capsule contains 114.0 mg of lactose (as monohydrate).
Croatian: Pomoćna tvar s poznatim učinkom Jedna tvrda kapsula sadrži 114 mg laktoze (u obliku hidrata).
English: if any member of your family (parents, grandparents, brothers or sisters) has died suddenly due to a heart problem or was born with heart problems.
Croatian: ako je netko od članova Vaše obitelji (roditelji, bake i djedovi, braća ili sestre) iznenada umro zbog tegoba sa srcem ili su rođeni s bolešću srca. ako Vam je liječnik rekao da imate visoke ili niske razine elektrolita u krvi, kao što su kalij ili magnezij. ako trenutno uzimate neki od sljedećih lijekova: (također vidjeti dio „Drugi lijekovi i SUSTIVA“):
English: Capsule shell: Gelatine, Sodium laurilsulfate, Yellow iron oxide (E172), Titanium dioxide (E171), Silicon dioxide (E551)
Croatian: Ovojnica kapsule: želatina, natrijev laurilsulfat, željezov oksid, žuti (E172), titanijev dioksid (E171), silicijev dioksid (E551)
English: Darunavir/ritonavir/Efavirenz (300 mg twice daily*/100 mg twice daily/600 mg once daily)
Croatian: darunavir/ritonavir/efavirenz (300 mg dvaput na dan*/100 mg dvaput na dan/600 mg jedanput na dan)
English: SUSTIVA 200 mg hard capsules efavirenz
Croatian: SUSTIVA 200 mg tvrde kapsule efavirenz
English: Bristol-Myers Squibb S.r.l.
Croatian: Bristol-Myers Squibb Pharmaceuticals Ltd.
English: SUSTIVA is recommended to be taken on an empty stomach preferably at bedtime.
Croatian: Preporučuje se uzimati lijek efavirenz na prazan želudac, po mogućnosti prije spavanja.
English: Fluconazole/Efavirenz (200 mg once daily/400 mg once daily)
Croatian: flukonazol/efavirenz (200 mg jedanput na dan /400 mg jedanput na dan)
English: Cmax: ↑ 49% (↑ 32 to ↑ 69)
Croatian: Cmax: ↑ 49% (↑ 32 do ↑ 69) efavirenz:
English: Paroxetine/Efavirenz (20 mg once daily/600 mg once daily)
Croatian: paroksetin/efavirenz (20 mg jedanput na dan/600 mg jedanput na dan)
English: These drugs include: - antiarrhythmics of classes IA and III, - neuroleptics, antidepressive agents, - certain antibiotics including some agents of the following classes: macrolides, fluoroquinolones,
Croatian: Navedeni lijekovi uključuju: - antiartimike skupina IA i III, - neuroleptike, antidepresive, - pojedine antibiotike koji uključuju neke tvari sljedećih klasa: makrolide, fluorokinolone te antimikotike koji sadrže imidazol i triazol, - pojedine antihistaminike koji nemaju sedativno djelovanje (terfenadin, astemizol), - cisaprid, - flekainid, - pojedine antimalarike, - metadon.
English: Cmin: ↓ 37% (↓ 17 to ↓ 52) Efavirenz:
Croatian: Cmax: ↓ 28% (↓ 7 do ↓ 44) Cmin: ↓ 37% (↓ 17 do ↓ 52) efavirenz:
English: SUSTIVA is for oral use.
Croatian: SUSTIVA se uzima kroz usta.
English: Simvastatin/Efavirenz (40 mg once daily/600 mg once daily)
Croatian: simvastatin/efavirenz (40 mg jedanput na dan/600 mg jedanput na dan)
English: Valproic acid/Efavirenz (250 mg twice daily/600 mg once daily)
Croatian: valproična kiselina/efavirenz (250 mg dvaput na dan/600 mg jedanput na dan)
English: Fosamprenavir/ritonavir/Efavirenz (700 mg twice daily/100 mg twice daily/600 mg once daily)
Croatian: fosamprenavir/ritonavir/efavirenz (700 mg dvaput na dan/100 mg dvaput na dan/600 mg jedanput na dan)
English: Voriconazole/Efavirenz (400 mg twice daily/300 mg once daily)
Croatian: vorikonazol/efavirenz (400 mg dvaput na dan/300 mg jedanput na dan)
English: a NC = F, noncompleter = failure.
Croatian: IDV + NRTI a NC = F, liječenje nije završeno = neuspješno.
English: INFORMATION IN BRAILLE SUSTIVA 100 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU SUSTIVA 100 mg
English: SUSTIVA may reduce the amount of posaconazole in your blood.
Croatian: SUSTIVA može smanjiti koncentraciju itrakonazola u krvi. posakonazol.
English: How to take SUSTIVA 4.
Croatian: 3. Kako uzimati lijek SUSTIVA 4. Moguće nuspojave
English: Each SUSTIVA hard capsule contains 200 mg of the active substance efavirenz.
Croatian: Jedna SUSTIVA tvrda kapsula sadrži 200 mg djelatne tvari efavirenz.
English: Each SUSTIVA hard capsule contains 50 mg of the active substance efavirenz.
Croatian: Jedna SUSTIVA tvrda kapsula sadrži 50 mg djelatne tvari efavirenz.
English: The capsule shell contains: gelatine, sodium laurilsulfate, yellow iron oxide (E172), titanium dioxide (E171) and silicon dioxide.
Croatian: Ovojnica kapsule sadrži: želatinu, natrijev laurilsulfat, žuti željezov oksid (E172), titanijev dioksid (E171) i silicijev dioksid.
English: Injection:
Croatian: simvastatin:
English: Efavirenz levels may increase on stopping St. John's wort and the dose of efavirenz may need adjusting.
Croatian: Nakon prestanka uzimanja gospine trave koncentracija efavirenza može se povećati, pa će biti potrebno prilagoditi njegovu dozu.
English: two 200 mg capsules one 600 mg tablet OR three 200 mg capsules *For information on the bioavailability of the capsule contents mixed with food vehicles, see section 5.2.
Croatian: *Za informacije o bioraspoloživosti sadržaja kapsule pomiješanog s hranom, vidjeti dio 5.2.
English: NAME OF THE MEDICINAL PRODUCT SUSTIVA 200 mg hard capsules efavirenz
Croatian: NAZIV LIJEKA SUSTIVA 200 mg tvrde kapsule efavirenz
English: Cmax: ↑ 50% (↑ 20 to ↑ 80)
Croatian: Cmax: ↑ 50% (↑ 20 do ↑ 80) (indukcija CYP2B6)
English: Serious psychiatric adverse reactions have been reported in patients treated with efavirenz.
Croatian: U bolesnika liječenih efavirenzom zabilježene su ozbiljne psihijatrijske nuspojave.
English: Indinavir/ritonavir/Efavirenz (800 mg twice daily/100 mg twice daily/600 mg once daily)
Croatian: indinavir/ritonavir/efavirenz (800 mg dvaput na dan/100 mg dvaput na dan/600 mg jedanput na dan)
English: METHOD AND ROUTE(S) OF ADMINISTRATION Oral use.
Croatian: 5. NAČIN I PUT(EVI) PRIMJENE LIJEKA Kroz usta.
English: NAME OF THE MEDICINAL PRODUCT SUSTIVA 50 mg hard capsules efavirenz
Croatian: NAZIV LIJEKA SUSTIVA 50 mg tvrde kapsule efavirenz
English: Telaprevir/Efavirenz (1,125 mg q8h/600 mg once daily)
Croatian: telaprevir/efavirenz (1125 mg svakih 8h/600 mg jedanput na dan)
English: Cmin: ↓ 62% (↓ 44 to ↓ 75) N-monodesmethyl diltiazem: AUC: ↓ 37% (↓ 17 to ↓ 52)
Croatian: AUC: ↓ 75% (↓ 59 do ↓ 84) Cmax: ↓ 64% (↓ 57 do ↓ 69) Cmin: ↓ 62% (↓ 44 do ↓ 75) N-monodezmetil diltiazem: AUC: ↓ 37% (↓ 17 do ↓ 52) Cmax: ↓ 28% (↓ 7 do ↓ 44) Cmin: ↓ 37% (↓ 17 do ↓ 52) efavirenz:
English: Each SUSTIVA hard capsule contains 100 mg of the active substance efavirenz.
Croatian: Jedna SUSTIVA tvrda kapsula sadrži 100 mg djelatne tvari efavirenz
English: Dose adjustment of pravastatin may be required (refer to the Summary of Product Characteristics for pravastatin).
Croatian: Može biti potrebno prilagođavati dozu pravastatina (vidjeti Sažetak opisa svojstava lijeka za pravastatin).
English: Efavirenz has not been studied in controlled studies in patients with advanced HIV disease, namely with CD4 counts < 50 cells/mm3, or in PI or NNRTI experienced patients.
Croatian: Nisu provedena kontrolirana ispitivanja efavirenza u bolesnika s uznapredovalom HIV bolešću, kao što su osobe s < 50 CD4 stanica/mm3, niti u bolesnika koji su već primali inhibitore proteaze ili NNRTI-je.
English: NAME OF THE MEDICINAL PRODUCT SUSTIVA 100 mg hard capsules efavirenz
Croatian: NAZIV LIJEKA SUSTIVA 100 mg tvrde kapsule efavirenz
English: Printing ink: Cochineal carminic acid (E120), Indigo carmine (E132), Titanium dioxide (E171)
Croatian: Tinta za označavanje: boja karmin crvena (E120), indigo karmin (E132), titanijev dioksid (E171) SUSTIVA 100 mg tvrde kapsule
English: Azithromycin/Efavirenz (600 mg single dose/400 mg once daily)
Croatian: Antibiotici azitromicin/efavirenz (600 mg jednokratna doza/400 mg jedanput na dan)
English: 3, or after failure of protease inhibitor (PI) containing regimens.
Croatian: 3, niti u bolesnika koji su već primali inhibitore proteaze ili NNRTI-je.
English: EFV + IDV + NRTIs 157 60 (52, 68) IDV + NRTIs a NC = F, noncompleter = failure.
Croatian: IDV + ZDV + 3TC a NC = F, liječenje nije završeno = terapijski neuspjeh. b C.I., interval pouzdanosti.
English: Cmax: ↓ 18% (↓ 59 to ↑ 12)
Croatian: AUC: ↓ 40% (↓ 26 do Cmax: ↓ 18% (↓ 59 do ↑ 12)
English: The dose of lopinavir/ritonavir tablets should be increased to 500/125 mg twice daily when co-administered with efavirenz 600 mg once daily.
Croatian: Koncentracije lopinavira: slično kao kod primjene lopinavira/ritonavira u dozi od 400/100 mg dvaput na dan bez efavirenza lopinavir/ritonavir tableta mora se povisiti na 500/125 mg dvaput na dan kada se primjenjuju istodobno s efavirenzom u dozi od 600 mg jedanput na dan.
English: Liver enzyme monitoring should be considered for patients without pre-existing hepatic dysfunction or other risk factors.
Croatian: U bolesnika koji nemaju postojeće poremećaje funkcije jetre ili druge čimbenike rizika mora se razmotriti praćenje jetrenih enzima.
English: Cmin: ↓ 43% (↓ 18 to ↓ 60) Efavirenz:
Croatian: Cmax: ↓ 35% (↓ 12 do ↓ 52) Cmin: ↓ 43% (↓ 18 do ↓ 60) efavirenz:
English: Cmin: ↓ 45% (↓ 31 to ↓ 56) Efavirenz:
Croatian: Cmax: ↓ 32% (↓ 15 do ↓ 46) Cmin: ↓ 45% (↓ 31 do ↓ 56) efavirenz:
English: Cmin: ↓ 46% (↓ 31 to ↓ 58) Efavirenz:
Croatian: Cmax: ↓ 29% (↓ 15 do ↓ 40) Cmin: ↓ 46% (↓ 31 do ↓ 58) efavirenz:
English: Pravastatin/Efavirenz (40 mg once daily/600 mg once daily)
Croatian: pravastatin/efavirenz (40 mg jedanput na dan/600 mg jedanput na dan)
English: Voriconazole/Efavirenz (200 mg twice daily/400 mg once daily)
Croatian: vorikonazol/efavirenz (200 mg dvaput na dan/400 mg jedanput na dan)
English: Slovenská republika Merck Sharp & Dohme, s. r. o. Tel.: +421 2 58282010 dpoc_czechslovak @merck.com
Croatian: Česká republika Merck Sharp & Dohme s.r.o. Tel.: +420 233 010 111 msd_cr@merck.com
English: Medicines that impact heart rhythm: - Medicines used to treat heart rhythm problems such as flecainide or metoprolol.
Croatian: lijekovi koji utječu na srčani ritam: - lijekovi koji se koriste za liječenje problema srčanog ritma: kao što su flekainid ili metoprolol. - lijekovi koji se koriste za liječenje depresije kao što su imipramin, amitriptilin ili klomipramin. - antibiotici, uključujući sljedeće tipove: makrolidi, fluorokinoloni ili imidazol
English: Cmax: ↓ 76% (↓ 63 to ↓ 79)
Croatian: Cmax: ↓ 76% (↓ 63 do ↓ 79) simvastatinska kiselina:
English: Proguanil: AUC: ↓ 43% (↓ 7 to ↓ 65)
Croatian: simeprevir: AUC: ↓ 71% (↓ 67 do ↓
English: Cmax: ↑ 23% (↓ 1 to ↑ 53) *
Croatian: Cmax: ↑ 23% (↓ 1 do ↑ 53)* efavirenz:
English: See package leaflet for further information.
Croatian: Vidjeti dio Opis odabranih nuspojava za detaljnije informacije.
English: AUC: ↓ 21% Cmax: ↔
Croatian: AUC: ↓ 21% Cmax: ↔ efavirenz:
English: Cmax: ↓ 20% (↓ 15 to ↓ 24)
Croatian: Cmax: ↓ 24 % (↓ 15 do
English: Efavirenz: AUC: ↑ 17% (↑ 6 to ↑ 29) **
Croatian: AUC: ↔* (↓ 9 do ↑ 10) Cmax: ↑ 17%* (↑ 8 do ↑ 27) Cmin: ↓ 42%* (↓ 31 do
English: The median increase from baseline in CD4+ count at 48 weeks of therapy was 238 cells/mm3 and the median increase in
Croatian: Medijan porasta broja CD4+ stanica od početne vrijednosti do 48. tjedna liječenja iznosio je 238 stanica/mm3, a medijan porasta postotka CD4+ stanica iznosio je 13%.
English: AUC: ↓ 36% C12: ↓ 21%
Croatian: AUC: ↓ 36% C12: ↓ 21% Cmax: ↓ 36% (indukcija UGT1A1)
English: OPIOIDS
Croatian: LIJEKA
English: EFV + IDV + NRTIs 157 60 (52, 68) IDV + NRTIs a
Croatian: EFV + IDV + NRTI IDV + NRTI
English: Cmin: ↓ 63% (↓ 44 to ↓ 75) Desacetyl diltiazem:
Croatian: Cmax: ↓ 60% (↓ 50 do ↓ 68) Cmin: ↓ 63% (↓ 44 do ↓ 75) dezacetil-diltiazem:
English: The capsule shell contains: gelatine, sodium laurilsulfate, yellow iron oxide (E172) and silicon dioxide.
Croatian: Ovojnica kapsule sadrži: želatinu, natrijev laurilsulfat, žuti željezov oksid (E172) i silicijev dioksid (E551).
English: Cmin: ↑ 12%*/** (↓16 to ↑49) (CYP3A4 induction).
Croatian: Cmax: ↑ 11% (↑ 6 do ↑ 16) Cmin: ↔ (indukcija CYP3A4)
English: The capsule shell contains: gelatine, sodium laurilsulfate, titanium dioxide (E171) and silicon dioxide.
Croatian: Ovojnica kapsule sadrži: želatinu, natrijev laurilsulfat, titanijev dioksid (E171) i silicijev dioksid (E551).
English: Norbuprenorphine:
Croatian: vorikonazol:
English: Efficacy results for studies ACTG 364 and 020 are found in Table 4.
Croatian: U Tablici 4 prikazani su rezultati djelotvornosti u ispitivanjima ACTG 364 i 020.
English: Ethinyloestradiol: AUC: ↔
Croatian: etinilestradiol:
English: Darunavir:
Croatian: rifabutin:
English: EU/1/99/110/003: bottle EU/1/99/110/004: blister
Croatian: EU/1/99/110/004 - blister
English: (CYP3A4 induction) In a study of HIV infected intravenous drug users, co-administration of efavirenz with methadone resulted in decreased plasma levels of methadone and signs of opiate withdrawal.
Croatian: Cmax: ↓ 45% (↓ 25 do ↓ 59) (indukcija CYP3A4) U ispitivanju intravenskih ovisnika zaraženih HIVom istodobna primjena efavirenza i metadona dovela je do sniženja koncentracije metadona u plazmi i znakova ustezanja od opijata.
English: (CYP3A induction by efavirenz)
Croatian: ↑ 50)b efavirenz:
English: Artemether:
Croatian: lorazepam:
English: Simvastatin acid: AUC: ↓ 58% (↓ 39 to ↓ 68)
Croatian: AUC: ↓ 58% (↓ 39 do
English: How to store SUSTIVA
Croatian: Kako čuvati lijek SUSTIVA
English: Efficacy results for studies ACTG 364 and 020 are found in Table 3.
Croatian: U Tablici 3 prikazani su rezultati djelotvornosti u ispitivanjima ACTG 364 i 020.
English: Weight and levels of blood lipids and glucose may increase during antiretroviral therapy.
Croatian: Tijekom antivirusne terapije mogu se povećati tjelesna težina i povisiti razine lipida i glukoze u krvi.
English: Cmax: ↑ 11% (↑ 6 to ↑ 16)
Croatian: AUC: ↑ 17% (↑ 6 do
English: Cmax: ↓ 13% (↓ 0 to ↓ 23)
Croatian: Cmax: ↓ 13% (↓ 0 do ↓ 23) 4-hidroksi atorvastatin:
English: Cmax: ↓ 34% (↓ 21 to ↓ 47)
Croatian: Cmax: ↓ 34% (↓ 21 do ↓ 47) hidroksibupropion:
English: Clarithromycin/Efavirenz (500 mg q12h/400 mg once daily)
Croatian: Preporuke za istodobnu primjenu s efavirenzom klaritromicin/efavirenz (500 mg svakih 12h/400 mg jedanput na dan)
English: Morning Cmax: ↑ 24% (↑ 12 to ↑ 38) Evening Cmax: ↔
Croatian: ritonavir: jutarnji AUC: ↑ 18% (↑ 6 do ↑ 33) večernji AUC: ↔ jutarnji Cmax: ↑ 24% (↑ 12 do ↑ 38) večernji Cmax: ↔ jutarnji Cmin: ↑ 42% (↑ 9 do
English: Tablet core
Croatian: Zatajenje jetre
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each hard capsule contains: efavirenz 100 mg.
Croatian: 2. KVALITATIVNI I KVANTITATIVNI SASTAV DJELATNIH TVARI Jedna tvrda kapsula sadrži 100 mg efavirenza.
English: Cmax: ↓ 12% (↓ 1 to ↓ 26)
Croatian: Cmax: ↓ 12% (↓ 1 do ↓ 26) 2-hidroksi atorvastatin:
English: Bottle: EU/1/99/110/008
Croatian: EU/1/99/110/008
English: Itraconazole/Efavirenz (200 mg q12h/600 mg once daily)
Croatian: Antifungalni lijekovi itrakonazol/efavirenz (200 mg svakih 12h/600 mg jedanput na dan)
English: Tell your doctor immediately.
Croatian: Odmah obavijestite svog liječnika.
English: Use in children of more than 2 years old
Croatian: Primjena u djece starije od 2 godine
English: AT/BE/BG/CY/EE/EL/ES/HR/HU/IE/LV/ LT/LU/MT/NL/RO/SI/SK Instituto Grifols, S.A.
Croatian: AT/BE/BG/CY/EE/EL/ES/HR/HU/IE/LV/ LT/LU/MT/NL/RO/SI/SK
English: There are two alternative treatment schedules:
Croatian: Postoje dva alternativna rasporeda terapije:
English: There are two groups:
Croatian: Postoje dvije skupine:
English: In particular, tell your doctor if you have:
Croatian: Obavezno obavijestite svog liječnika ako imate:
English: The following information is intended for healthcare professionals only (see section 3 for further information):
Croatian: Sljedeće informacije namijenjene su samo zdravstvenim radnicima (vidjeti dio 3 za dodatne informacije):
English: ● Coombs test positive
Croatian: • pozitivan Coombsov test
English: The treatment effect should be evaluated after each cycle; if no treatment effect is seen after 6 months, the treatment should be discontinued.
Croatian: Terapijski učinak treba procijeniti nakon svakog ciklusa; ako se terapijski učinak ne opazi nakon 6 mjeseci, liječenje treba prekinuti.
English: Allergic reactions are rare.
Croatian: Alergijske reakcije su rijetke.
English: Kawasaki disease
Croatian: Kawasakijeva bolest
English: Date of latest renewal: 24 April 2017
Croatian: Datum posljednje obnove odobrenja: 24. travnja 2017.
English: ● feeling cold
Croatian: ● osjećaj hladnoće