FrancophonIA/ELRC3.0 huggingface dataset:
English: Capsule shell gelatin titanium dioxide (E171) brilliant blue FCF (E133)
Maltese: Kontenut tal-kapsula maize starch magnesium stearate Il-qoxra tal-kapsula ġelatin titanium dioxide (E171) brilliant blue FCF (E133)
English: • Periodic Safety Update Reports
Maltese: • Rapporti Perjodiċi Aġġornati dwar is-Sigurtà
English: • Do not use Wilzin after the expiry date stated on the bottle and the carton, after EXP.
Maltese: • Tużax Wilzin wara d-data ta' skadenza li tidher fuq Il-flixkun u l-kartuna, wara EXP.
English: The weight of evidence, from in vitro and in vivo tests, suggests that zinc has no clinically relevant genotoxic activity.
Maltese: Il-piż ta' l-evidenza, minn testijiet in vitro u in vivo, tissuggerixxi li zinc ma għandu l-ebda attività genotossika klinikament relevanti.
English: It is very important to continue anti-copper therapy during pregnancy.
Maltese: Huwa importanti ħafna li tkompli t-terapija kontra copper waqt it-tqala.
English: Conversely, the effectiveness of some medicines, such as iron, tetracyclines or fluoroquinolones (antibiotics), may be reduced by Wilzin.
Maltese: Minn naħa l-oħra, l-effettività ta' ċertu mediċini, bħal ħadid, tetracyclines, fluoroquinolones (antibijotiċi) jista' jitnaqqas b'Wilzin.
English: Pharmacotherapeutic group: various alimentary tract and metabolism products, ATC code: A16AX05.
Maltese: Kategorija farmakoterapewtika: prodotti ta' partijiet varji tal-apparat alimentari u tal-metaboliżmu, Kodiċi ATC:
English: Anaemia may be micro-, normo- or macrocytic and is often associated with leukopenia.
Maltese: Anemija tista' tkun mikro-, normo- jew makroċitika u hija ta' spiss assoċjata ma' lewkopenja.
English: Blood and lymphatic system disorders uncommon: sideroblastic anaemia, leukopenia
Maltese: anemija sideroblastika, lewkopenja
English: Printing ink black iron oxide (E172) shellac
Maltese: Inka ta' l-istampar black iron oxide (E172) shellac
English: Tél/Tel: +32 2 46101 36 Belgique/Belgien
Maltese: +32 2 46101 36 Belgique/Belgien
English: Laboratory follow-up including haematological surveillance and lipoproteins determination should also be performed in order to detect early manifestations of copper deficiency, such as anaemia and/or leukopenia resulting from bone marrow depression, and decrease in HDL cholesterol and HDL/total cholesterol ratio.
Maltese: Eżamijiet ta' wara fil-laboratorju li jinkludu sorveljanza ematoloġika u kejl ta' lipoproteini għandhom isiru wkoll sabiex tiskopri manifestazzjonijiet bikrin ta' defiċjenza ta' copper, bħal anemija u/jew lewkopinja kkawżati minn depressjoni tal-mudullun, u tnaqqis fil-kolesterol HDL u l-proporzjon HDL/kolesterol totali.
English: The aim of the treatment is to maintain the plasma free copper (also known as non-ceruloplasmin plasma copper) below 250 microgram/l (normal: 100-150 microgram/l) and the urinary copper excretion below 125 microgram/24 h (normal: < 50 microgram/24 h).
Maltese: L-għan tat-trattament huwa li jżomm il-livell ta' copper liberu fil-plażma (magħruf ukoll bħala nonceruloplasmin copper fil-plażma) anqas minn 250 mikrogramma/l (normali: 100-150 mikrogramma/l) u tneħħija ta' copper fl-awrina anqas minn 125 mikrogramma/24 siegħa (normali: < 50 mikrogramma/24 siegħa).
English: Repeat-dose toxicity studies have established that the NOEL (No Observed Effect Level) is about 95 mg zinc/kg body weight (about 48 times the human therapeutic dose).
Maltese: Studji tossikoloġici b'dożi rrepetuti stabbilixxew li NOEL(No Observed Effect Level) hija madwar 95 mg zinc/kg piż tal-ġisem (madwar 48 darba d-doża terapewtika umana).
English: • Risk Management Plan (RMP)
Maltese: • Pjan tal-Ġestjoni tar-Riskju (RMP) Mhux applikabbli.
English: 5.2 Pharmacokinetic properties
Maltese: .2 Tagħrif farmakokinetiku
English: The non-ceruloplasmin plasma copper is calculated by subtracting the ceruloplasmin-bound copper from the total plasma copper, given that each milligram of ceruloplasmin contains 3 micrograms of copper.
Maltese: Non-ceruloplasmin copper fil-plażma huwa kkalkulat billi jitnaqqas copper marbut ma ceruloplasmin mit-total ta' copper fil-plażma, la kemm-il darba kull milligramma ta' ceruloplasmin fiha 3 mikrogrammi ta' copper.
English: Capsule with orange opaque cap and body, imprinted "93-377”.
Maltese: Kapsula b'kappa u korp ta' lewn oranġjo opaka, li fuqha hemm stampat "93-377”.
English: The capsule shell contains sunset yellow FCF (E110), which may cause allergic reactions.
Maltese: Il-qoxra tal-kapsula tinkludi sunset yellow FCF (E110) li jista' jikkaġuna reazzjonijiet allerġiċi.
English: The other ingredients are maize starch and magnesium stearate.
Maltese: Is-sustanzi l-oħra huma maize starch u magnesium stearate.
English: Wilzin is indicated in the treatment of Wilson's disease, which is a rare inherited defect in copper excretion.
Maltese: Wilzin huwa indikat għat-trattament tal-marda ta' Wilson, li hi kundizzjoni rari li tintired fleskrezzjoni ta' copper.
English: Wilson's disease (hepatolenticular degeneration) is an autosomal recessive metabolic defect in hepatic excretion of copper in the bile.
Maltese: Il-marda ta' Wilson (deġenerazzjoni epatolentikulari) hija difett metaboliku awtosomali reċessiv fleskrezzjoni ta' copper ġol-bile.
English: affects 1 to 10 users in 100
Maltese: jaffettwa minn 1 sa 10 utenti f'100
English: ANNEX II
Maltese: ANNESS II
English: Treatment of Wilson's disease.
Maltese: Trattament għal marda ta' Wilson.
English: The absorption of zinc may be reduced by iron and calcium supplements, tetracyclines and phosphorus-containing compounds, while zinc may reduce the absorption of iron, tetracyclines, fluoroquinolones.
Maltese: L-assorbiment ta' zinc jista' jiġi mnaqqas minn supplimenti ta'iron u ta' calcium, tetracyclines u prodotti li fihom phosphorus, filwaqt li zinc jista' jnaqqas l-assorbiment ta' iron, tetracyclines u fluoroquinolones.
English: 4.9 Overdose
Maltese: .9 Doża eċċessiva
English: OUTER CARTON BOX AND BOTTLE LABEL (Wilzin 25 mg hard capsules)
Maltese: KAXXA TAL-KARTUN TA' BARRA U T-TIKKETTA TAL-FLIXKUN (Wilzin 25 mg kapsuli iebsin)
English: OUTER CARTON BOX AND BOTTLE LABEL (Wilzin 50 mg hard capsules)
Maltese: KAXXA TAL-KARTUN TA' BARRA U T-TIKKETTA TAL-FLIXKUN (Wilzin 50 mg kapsuli iebsin)
English: It is available in packs of 250 hard capsules in a polyethylene bottle closed by a polypropylene and polyethylene closure.
Maltese: Huwa jiġi f'pakketti ta' 250 kapsuli iebsin fi flixkun ta' polyethylene li jingħalaq b'tapp ta' polypropylene u polyethylene.
English: Wilzin belongs to a group of medicines called Various Alimentary Tract and metabolism products.
Maltese: Wilzin jappartjeni għal grupp ta' mediċini li jissejħu prodotti Diversi tal-Passaġġ Alimentari u lmetaboliżmu.
English: The most common undesirable effect is gastric irritation.
Maltese: L-aktar effett mhux mixtieq komuni hija l-irritazzjoni gastrika.
English: Values of urinary zinc above 2 mg/24 h and of plasma zinc above 1250 microgram/l generally indicate adequate compliance.
Maltese: Livelli ta' zinc fl-awrina ‘il fuq min 2mg/24 siegħa u ta' zinc fil-plażma ‘il fuq minn 1250 mikrogrammi/l ġeneralment jindikaw konformità adegwata.
English: The oral LD50 is approximately 300 mg zinc/kg body weight (about 100 to 150 times the human therapeutic dose).
Maltese: L-LD50 orali hija bejn wieħed u ieħor 300mg zinc/kg piż tal-ġisem (madwar 100 sa 150 darba d-doża terapewtika umana).
English: It ranges from 30 to 60% with usual dietary intake (7-15 mg/d) and decreases to 7% with pharmacological doses of 100 mg/d.
Maltese: Ivarja fuq medda minn 30 sa 60% b'teħid fid-dieta tas-soltu (715mg/jum) u jonqos għal 7% b'dożi farmakologiċi ta' 100mg/jum.
English: • For adults: The usual dose is 1 hard capsule of Wilzin 50 mg (or 2 hard capsules of Wilzin 25 mg) three times daily with a maximum dose of 1 hard capsule of Wilzin 50 mg (or 2 hard capsules of Wilzin 25 mg) five times daily.
Maltese: Id-doża li ġeneralment tingħata hi ta' kapsula iebsa 1 ta' Wilzin 50 mg (jew 2 kapsuli iebsin ta' Wilzin 25 mg) tliet darbiet kuljum sa doża massima ta' kapsula iebsa 1 ta' Wilzin 50 mg (jew 2 kapsuli iebsin ta' Wilzin 25 mg) ħames darbiet kuljum.
English: • After Wilzin intake, gastric irritation may occur, especially at the beginning of treatment.
Maltese: • Wara t-teħid ta' Wilzin, jista' jkun hemm irritazzjoni gastrika speċjalment fil-bidu tat-trattament.
English: CLINICAL PARTICULARS
Maltese: KLINIKU
English: UNIQUE IDENTIFIER - HUMAN READABLE DATA
Maltese: IDENTIFIKATUR UNIKU - DATA LI TINQARA MILL-BNIEDEM
English: Therefore, breast-feeding should be avoided during Wilzin therapy.
Maltese: Ghaldaqstant, it-treddigħ għandu jiġi evitat waqt t-terapija b'Wilzin.
English: Reproduction toxicology studies performed with different zinc salts showed no clinically relevant evidence of embryotoxicity, foetotoxicity or teratogenicity.
Maltese: Studji tossikoloġiċi fuq ir-riproduzzjoni magħmulin b'imluħa ta' zinc differenti ma wrew l-ebda evidenza klinikament relevanti ta' tossiċità fl-embrju, tossiċità fil-fetu jew teratoġeniċità.
English: Reported adverse reactions are listed below, by system organ class and by frequency.
Maltese: Effetti avversi rrapportati huma elenkati hawn taħt, skond il-klassi tas-sistema ta' l-organi u l-frekwenza.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines webportal.
Maltese: Ir-rekwiżiti biex jiġu ppreżentati rapporti perjodiċi aġġornati dwar is-sigurtà għal dan il-prodott mediċinali huma mniżżla fil-lista tad-dati ta' referenza tal-Unjoni (lista EURD) prevista skont lArtikolu 107c(7) tad-Direttiva 2001/83/KE u kwalunkwe aġġornament sussegwenti ppubblikat fuq il-portal elettroniku Ewropew tal-mediċini.
English: affects 1 to 10 users in 10,000
Maltese: • rari jaffettwa minn utent 1 sa 10 utenti f'10,000
English: Wilzin 25 mg is an aqua blue hard capsule imprinted "93-376”.
Maltese: Id-Dehra ta' Wilzin u l-kontenuti tal-pakkett Wilzin 25 mg hija kapsula iebsa ta' lewn ikħal li fuqha hemm stampat "93-376”.
English: STATEMENT OF ACTIVE SUBSTANCE(S)
Maltese: Sustanza(i) mhux attiva(i)
English: Manufacturer
Maltese: Manifattur
English: Fractional zinc absorption is negatively correlated with zinc intake.
Maltese: Assorbiment frazzjonali ta' zinc huwa korelat b'mod negattiv mat-teħid ta' zinc.
English: Reporting suspected adverse reactions after authorisation of the medicinal product is important.
Maltese: Huwa importanti li jiġu rrappurtati reazzjonijiet avversi suspettati wara l-awtorizzazzjoni tal-prodott mediċinali.
English: • For children and adolescents: The usual dose is: - from 1 to 6 years: 1 hard capsule of Wilzin 25 mg twice daily - from 6 to 16 years if bodyweight under 57 kg: 1 hard capsule of Wilzin 25 mg three times daily - from 16 years or if bodyweight above 57 kg: 2 hard capsules of Wilzin 25 mg or 1 hard capsule of Wilzin 50 mg three times daily.
Maltese: Id-doża li ġeneralment tingħata hi: - minn 1 sa 6 snin: Kapsula iebsa 1 ta' Wilzin 25 mg darbtejn kuljum - minn 6 sa 16-il sena ta' piż tal-ġisem huwa taħt 57 kg: Kapsula iebsa 1 ta' Wilzin 25 mg tliet darbiet kuljum - minn 16-il sena jew jekk il-piż tal-ġisem huwa aktar minn 57 kg: 2 kapsuli iebsin ta' Wilzin 25 mg jew kapsula iebsa ta' Wilzin 50 mg tliet darbiet kuljum.
English: The printing ink contains black iron oxide (E172) and shellac.
Maltese: L-inka ta' l-istampar fiha black iron oxide (E172) u shellac.
English: Each hard capsule contains 25 mg of zinc (corresponding to 83.92 mg of zinc acetate dihydrate) or 50 mg of zinc (corresponding to 167.84 mg of zinc acetate dihydrate).
Maltese: Kull kapsula iebsa tikkonsisti minn 25 mg ta' zinc (li jikkorispondi għal 83.92 mg ta' zinc acetate dihydrate) jew 50 mg ta' zinc (li jikkorispondi għal 167.84 mg ta' zinc acetate dihydrate).
English: 5.1 Pharmacodynamic properties
Maltese: 5.1 Tagħrif farmakodinamiku
English: LIST OF EXCIPIENTS
Maltese: KLASSIFIKAZZJONI ĠENERALI
English: A dose of 25 mg 3 times daily is usually effective but the dose should be adjusted to copper levels (see section 4.4 and section 4.6).
Maltese: Doża ta' 25mg 3 darbiet kuljum hija ġeneralment effettiva iżda d-doża għandha tiġi aġġustata mal-livelli ta' copper (ara sezzjoni 4.4 u sezzjoni 4.6).
English: Wilzin is a life-long therapy.
Maltese: - Din il-mediċina ġiet mogħtija lilek.
English: 250 hard capsules.
Maltese: Kull flixkun fih 250 kapsula.
English: Wilzin 50 mg hard capsules
Maltese: Wilzin 50 mg kapsuli iebsin
English: Batch
Maltese: Treddigħ
English: Other anti-copper agents
Maltese: Mediċini anti-copper oħrajn
English: Each hard capsule contains 25 mg of zinc (corresponding to 83.92 mg of zinc acetate dihydrate).
Maltese: Kull kapsula iebsa tikkonsisti minn 25 mg ta' zinc (li jikkorispondi għal 83.92 mg ta' zinc acetate dihydrate)
English: INSTRUCTIONS ON USE
Maltese: MANIFATTUR RESPONSABBLI
English: PHARMACEUTICAL PARTICULARS
Maltese: FARMAKOLOĠIKU
English: Capsule with aqua blue opaque cap and body, imprinted "93-376”.
Maltese: Kapsula b'kappa u korp ta' lewn ikħal opak, li fuqha hemm stampat "93-376”.
English: Wilzin 25 mg hard capsules
Maltese: Wilzin 25 mg kapsuli iebsin
English: Breast-feeding Breast-feeding should be avoided if you are on Wilzin therapy.
Maltese: It-treddigħ għandu jiġi evitat jekk qegħda fuq terapija b'Wilzin.
English: Wilzin is available in hard capsules of 25 mg or 50 mg.
Maltese: Wilzin hu disponibbli f'kapsuli iebsin ta' 25 mg jew 50 mg.
English: The level of hepatic copper cannot be used to manage therapy since it does not differentiate between potentially toxic free copper and metallothionein bound copper.
Maltese: Il-livell ta' copper fil-fwied ma jistax jiġi użat biex timmaniġġa t-terapija peress li dan ma jiddistingwix bejn copper liberu li huwa potenzjalment tossiku u copper marbut ma' metallothionein.
English: affects 1 to 10 users in 1,000
Maltese: • mhux komuni jaffettwa minn 1 sa 10 utenti f'1,000
English: Wilzin 25 mg hard capsules Wilzin 50 mg hard capsules zinc
Maltese: Wilzin 25 mg kapsuli iebsin Wilzin 50 mg kapsuli iebsin
English: Wilzin 25 mg hard capsules Zinc
Maltese: Wilzin 25 mg kapsuli iebsin Zinc
English: Wilzin 50 mg hard capsules Zinc
Maltese: Wilzin 50 mg kapsuli iebsin Zinc
English: You may need to read it again.
Maltese: DATA TA' META ĠIET RIVEDUTA
English: Three cases of acute oral overdose with zinc salts (sulphate or gluconate) have been reported in the literature.
Maltese: Tliet każi ta' doża eċċessiva orali akuta b'ta' zinc salts (sulphate jew gluconate) ġew irraportati fil-letteratura medika.
English: Each hard capsule contains 50 mg of zinc (corresponding to 167.84 mg of zinc acetate dihydrate) .
Maltese: Kull kapsula iebsa tikkonsisti minn 50 mg ta' zinc (li jikkorispondi għal 167.84 mg ta' zinc acetate dihydrate)
English: Detailed information on this medicine is available on the European Medicines Agency (EMA) web site: http://www.ema.europa.eu.
Maltese: Informazzjoni dettaljata dwar din il-mediċina tinsab fuq il-website ta' l-Aġenzija Ewropeja dwar ilMediċini (EMA) http://www.ea.europa.eu/.
English: Take special care with Wilzin
Maltese: Oqgħod attent ħafna b'Wilzin
English: HOW TO STORE WILZIN
Maltese: X'fih Wilzin
English: Date of first authorisation: 13 October 2004 Date of latest renewal: 13 October 2009
Maltese: DATA TA' L-EWWEL AWTORIZZAZZJONI/TIĠDID TA' L-AWTORIZZAZZJONI Data tal-ewwel awtorizzazzjoni: 13 t'Ottubru 2004
English: No conventional carcinogenicity study has been conducted with zinc acetate dihydrate.
Maltese: L-ebda studju konvenzjonali fuq il-karċinoġeniċità ma ġie magħmul b'zinc acetate dihydrate.
English: PHARMACOLOGICAL PROPERTIES
Maltese: GĦAMLA FARMAĊEWTIKA
English: • Children and adolescents:
Maltese: • Għall-adulti:
English: It is extremely important that pregnant Wilson's disease patients continue their therapy during pregnancy.
Maltese: Huwa importanti ħafna li pazjenti tqal bil-marda ta' Wilson ikomplu t-terapija tagħhom matul it-tqala.
English: The usual dose is 50 mg 3 times daily with a maximum dose of 50 mg 5 times daily.
Maltese: Id-doża tas-soltu hija ta' 50 mg 3 darbiet kuljum b'doża massima ta' 50mg 5 darbiet kuljum.
English: Important information about some of the ingredients of Wilzin Wilzin 50 mg hard capsules contains sunset yellow FCF (E110) which may cause allergic reactions.
Maltese: Tagħrif importanti dwar xi wħud mis-sustanzi ta' Wilzin Il-kapsuli iebsin ta' Wilzin 50 mg fihom sunset yellow FCF (E110) li jista' jikkawża reazzjonijiet allerġiċi.
English: It is also possible to take Wilzin with a little protein, such as meat (see section 4.5).
Maltese: Wilzin jittieħed ma' ftit proteina, bħal ma' huwa l-laħam (ara sezzjoni 4.5).
English: Recordati Rare Diseases Immeuble “Le Wilson” 70, avenue du Général de Gaulle F-92800 Puteaux France
Maltese: Recordati Rare Diseases Immeuble "Le Wilson" 70, avenue du Général de Gaulle F-92800
English: Therapeutic monitoring
Maltese: TAL-PRODOTT MEDIĊINALI
English: When switching a patient on chelating treatment to Wilzin for maintenance therapy, the chelating treatment should be maintained and co-administered for 2 to 3 weeks since this is the time it takes for the zinc treatment to induce maximum metallothionein induction and full blockade of copper absorption.
Maltese: Meta pazjent ikun qed jinqaleb minn fuq trattament kelanti għal fuq Wilzin bħala terapija ta' manteniment, il-trattament kelanti għandu jitkompla u jingħata ma Wilzin għal 2-3 gimagħat billi dan huwa ż-żmien li jieħu t-trattament b'zinc biex jikkawża induzzjoni massima ta'metallothionein u impediment totali ta' l-assorbiment ta' copper.
English: 4.6 Pregnancy and lactation
Maltese: 4.6 Tqala u Treddigħ
English: Pharmacodynamic investigations of copper metabolism in patients with Wilson's disease included determinations of net copper balance and radiolabelled copper uptake.
Maltese: Stħarriġ farmakodinamiku tal-metaboliżmu ta' copper f'pazjenti bil-marda Wilson kienu jinkludu lmiżura tal-bilanċ nett ta' copper u t-teħid ta' copper radjutikkettat.
English: Please consult your doctor before taking any other medicines which may reduce the effectiveness of Wilzin, such as iron, calcium supplements, tetracyclines (antibiotics) or phosphorus.
Maltese: Jekk jogħġbok ikkonsulta mat-tabib tiegħek qabel ma tieħu mediċini oħra li jistgħu jnaqqsu leffettività ta' Wilzin, bħal ħadid, supplimenti tal-kalċju, tetracyclines (antibijotiċi) jew phosphorus.
English: It allows continued monitoring of the benefit/risk balance of the medicinal product.
Maltese: Dan jippermetti monitoraġġ kontinwu tal-bilanċ bejn il-benefiċċju u r-riskju tal-prodott mediċinali.
English: The active moiety in zinc acetate dihydrate is zinc cation, which blocks the intestinal absorption of copper from the diet and the reabsorption of endogenously secreted copper.
Maltese: Il-frazzjoni attiva f'zinc acetate dihydrate hija ta' zinc ketajin, li timpedixxi l-assorbiment intestinali ta' copper mid-dieta u r-riassorbiment ta' copper merħi mill-ġisem.
English: In the blood, about 80% of absorbed zinc is distributed to erythrocytes, with most of the remainder being bound to albumin and other plasma proteins.
Maltese: Fid-demm, madwar 80% ta' zinc assorbit huwa mqassam liċ-ċelloli l-ħomor tad-demm, bilmaggoranza tal-kumplament ikun marbut ma' albumin u l-proteini tal-plażma oħrajn.
English: Two patients of a series of 16 died from hepatic decompensation and advanced portal hypertension after being changed from penicillamine to zinc therapy.
Maltese: Żewġ pazjenti minn 16-il pazjent mietu minn dekompensazzjoni tal-fwied u pressjoni għolja portali avvanzata wara li nqalbu minn fuq penicillamine għal fuq terapija b'zinc.
English: Unabsorbed copper is then eliminated in the stool.
Maltese: Copper li mhux assorbit mbagħad jiġi eliminat fl-ippurgar.
English: Five miscarriages and 2 birth defects (microcephaly and correctable heart defect) were reported in 42 pregnancies.
Maltese: Ħames korrimenti u 2 difetti tattwelid (mikrokefalija u difett fil-qalb korregibbli) ġew irrapportati f'42 tqala.
English: The recommended dosage is as follows: - from 1 to 6 years: 25 mg twice daily - from 6 to 16 years if bodyweight under 57 kg: 25 mg three times daily - from 16 years or if bodyweight above 57 kg: 50 mg three times daily.
Maltese: Id-doża rakkomandata hija kif ġejja: - minn 1 sa 6 snin: 25 mg darbtejn kuljum - minn 6 sa 16-il sena jekk il-piż tal-ġisem jkun taħt il-57 kg: 25 mg tliet darbiet kuljum. - minn 16-il sena jew jekk il-piż tal-ġisem jkun ‘il fuq minn 57 kg: 50 mg tliet darbiet kuljum.
English: Recordati Rare Diseases Immeuble “Le Wilson” 70, avenue du Général de Gaulle F-92800 Puteaux France or
Maltese: Recordati Rare Diseases Immeuble “Le Wilson“ 70, avenue du Général de Gaulle F-92800
English: The liver is the main storage for zinc and hepatic zinc levels are increased during maintenance therapy with zinc.
Maltese: Il-fwied huwa lħażna prinċipali għal zinc u l-livelli ta' zinc fil-fwied jiżdiedu waqt terapija ta' manteniment b'zinc.
English: For the different dose regimens Wilzin is available in hard capsules of 25 mg or 50 mg.
Maltese: Għall-programmi ta' dożi differenti Wilzin jiġi f'kapsuli iebsin ta' 25 mg jew 50 mg.
English: Another adolescent who ingested 4 g of zinc had serum zinc level of about 50 mg/l 5 hours later and only experienced severe nausea, vomiting and dizziness.
Maltese: Adolexxenti ieħor li bela' 4 g ta' zinc kellu l-livell ta' zinc fis-serum ta' madwar 50mg/l 5-il siegħa wara u sofra biss dardir qawwi, rimettar u sturdament.
English: MANUFACTURER'S BATCH NUMBER
Maltese: NUMRU TAL-LOTT
English: Bone marrow examination usually reveals characteristic "ringed sideroblasts" (i.e. developing red blood cells containing iron-engorged paranuclear mitochondria).
Maltese: Eżami tal-mudullun ġeneralment juri l-karatteristiċi “sideroblasti biċ-ċrieki” (i.e. ċelloli tad-demm ħomor li qed jiżviluppaw li fihom mitokondrija paranuklejari mimlijin bil-ħadid).
English: If you have been prescribed Wilzin with another anti-copper agent, such as penicillamine, keep an interval of at least 1 hour between the two medicines.
Maltese: Jekk se tingħata mediċina oħra ma Wilzin li taħdem kontra copper, bħalma hi penicillamine, żomm intervall ta' lanqas siegħa bejn iż-żewġ mediċini.
English: Excipients: Each capsule contains 1.75 mg of sunset yellow FCF (E110)
Maltese: Kull kapsula fiha 1.75 mg ta' sunset yellow FCF (E110) Għal-lista kompleta ta' sustanzi mhux attivi, ara sezzjoni 6.1.
English: The bound copper is then eliminated in the stool following desquamation of the intestinal cells.
Maltese: Dan biex jiġi żgurat li tirċievi trattament sodisfaċenti.
English: What Wilzin is and what it is used for Before you take Wilzin How to take Wilzin Possible side effects 5 How to store Wilzin Further information
Maltese: X'inhu Wilzin u għal xiex jintuża Qabel ma' tieħu Wilzin Kif għandek tieħu Wilzin Effetti sekondarji li jista' jkollu 5
English: Death occurred in a 35 year-old woman on the fifth day after ingestion of 6 g of zinc (40 times the proposed therapeutic dose) and was attributed to renal failure and haemorrhagic pancreatitis with hyperglycaemic coma.
Maltese: Il-mewt seħħet f'mara ta' 35 sena fil-ħames jum wara li ħadet 6 g zinc (40 darba ddoża terapewtika proposta) u kienet attribwita għal insuffiċjenza renali u l-infjammazzjoni emorraġika tal-frixa b'koma ipergliċemika.
English: Nevertheless, while awaiting zinc induced duodenal metallothionein production and consequential effective inhibition of copper absorption, zinc acetate dehydrate could be administered initially in symptomatic patients in combination with a chelating agent.
Maltese: Madankollu, waqt l-istennija tal-produzzjoni ta'metallothionein fid-duwodenu kawżata minn zinc u limpediment effettiv ta' l-assorbiment ta' copper b'konsegwenza ta dan, zinc acetate dihydrate jista' jingħata inizjalment f'pazjenti sintomatici flimkien ma' mediċina kelanti.
English: Heavy metal chelation therapy should be considered if plasma zinc levels are markedly elevated (> 10 mg/l).
Maltese: Terapija ta' kelazzjoni b'metalli tqal għandha tiġi kkunsidrata jekk il-livelli ta' zinc fil-plażma jibqgħu għoljin ħafna (> 10mg/l).