FrancophonIA/ELRC3.0 huggingface dataset:
English: Reconstitute 1,000 mg vials with 40 ml of sodium chloride 9 mg/ml (0.9 %) solution for injection, without preservative, resulting in a solution containing 25 mg/ml pemetrexed.
Croatian: Bočice od 1000 mg rekonstituirajte s 40 ml otopine natrijeva klorida za injekciju od 9 mg/ml (0,9%), bez konzervansa, čime se dobiva otopina koja sadrži 25 mg/ml pemetrekseda.
English: Reconstitute each 100 mg vial with 4.2 ml of 9 mg/ml (0.9 %) sodium chloride solution for injection, without preservative, resulting in a solution containing 25 mg/ml pemetrexed.
Croatian: Svaku bočicu od 100 mg rekonstituirajte s 4,2 ml otopine natrijeva klorida za injekciju od 9 mg/ml (0,9%), bez konzervansa, čime se dobiva otopina koja sadrži 25 mg/ml pemetrekseda.
English: Constipation Stomatitis/
Croatian: • zatajenje bubrega
English: Pemetrexed at a dose of 500 mg/m² was studied as a single-agent in 64 chemonaive patients with malignant pleural mesothelioma.
Croatian: U 64 bolesnika s malignim pleuralnim mezoteliomom koji prethodno nisu primali kemoterapiju pemetreksed je ispitan u dozi od 500 mg/m² u monoterapiji.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each vial contains 1,000 mg of pemetrexed (as pemetrexed disodium hemipentahydrate).
Croatian: Jedna bočica sadrži 1000 mg pemetrekseda (u obliku pemetrekseddinatrija hemipentahidrata).
English: Sant Boi de Llobregat
Croatian: Las Salinas, Sant Boi de Llobregat 08830 Barcelona
English: Reconstitute each 500 mg vial with 20 ml of 9 mg/ml (0.9 %) sodium chloride solution for injection, without preservative, resulting in a solution containing 25 mg/ml pemetrexed.
Croatian: Svaku bočicu od 500 mg rekonstituirajte s 20 ml otopine natrijeva klorida za injekciju od 9 mg/ml (0,9%), bez konzervansa, čime se dobiva otopina koja sadrži 25 mg/ml pemetrekseda.
English: Reconstitute each 1,000 mg vial with 40 ml of 9 mg/ml (0.9 %) sodium chloride solution for injection, without preservative, resulting in a solution containing 25 mg/ml pemetrexed.
Croatian: Svaku bočicu od 1000 mg rekonstituirajte s 40 ml otopine natrijeva klorida za injekciju od 9 mg/ml (0,9%), bez konzervansa, čime se dobiva otopina koja sadrži 25 mg/ml pemetrekseda.
English: Common Neuropathy-sensory 7.4
Croatian: Poremećaji živčanog sustava često senzorna neuropatija
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each vial contains 100 mg of pemetrexed (as pemetrexed disodium hemipentahydrate).
Croatian: Jedna bočica sadrži 100 mg pemetrekseda (u obliku pemetrekseddinatrija hemipentahidrata).
English: − Radiation pneumonitis (scarring of the air sacs of the lung associated with radiation therapy)
Croatian: • radijacijski pneumonitis (stvaranje ožiljaka na mjehurićima u plućima (alveolama) povezano s terapijom zračenjem) može se pojaviti u bolesnika koji su zračeni prije, tijekom ili nakon liječenja lijekom Pemetrexed medac.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each vial contains 500 mg of pemetrexed (as pemetrexed disodium hemipentahydrate).
Croatian: Jedna bočica sadrži 500 mg pemetrekseda (u obliku pemetrekseddinatrija hemipentahidrata).
English: Name and address of the manufacturers responsible for batch release Synthon Hispania, S.L.
Croatian: Synthon Hispania, S.L.
English: − nausea
Croatian: (ezofagusa).
English: − kidney failure
Croatian: Prijavljivanje nuspojava
English: OTHER sun as symbol moon as symbol
Croatian: sunce kao simbol mjesec kao simbol
English: The volume of distribution (Vss) is approximately 21 litres.
Croatian: Volumen distribucije (Vss) iznosi približno 21 litru.
English: Take the card
Croatian: Uzmite karticu
English: Your doctor will decide how long you must continue treatment for.
Croatian: Vaš liječnik će odlučiti koliko dugo morate nastaviti liječenje.
English: Try to take the tablets at the same times every day to have the best treatment effect.
Croatian: Pokušajte tablete uzimati svaki dan u isto vrijeme kako biste postigli najbolji učinak liječenja.
English: • The use of coagulation tests and their interpretation
Croatian: • Uporaba testova koagulacije i njihova interpretacija
English: • age ≥ 75 years
Croatian: • dob ≥ 75 godina
English: A risk to newborns and infants cannot be excluded.
Croatian: Ne može se isključiti rizik za novorođenče i dojenče.
English: Ethnic origin and race
Croatian: Etničko podrijetlo i rasa
English: The reduction in exposure is not considered clinically relevant.
Croatian: Smanjenje u izloženosti ne smatra se klinički značajnim.
English: Median [5th, 95th Percentile]
Croatian: Medijan [5., 95. percentil]
English: You should not take Eliquis if you are pregnant.
Croatian: Ne smijete uzimati Eliquis ako ste trudni.
English: Date of latest renewal: 14 January 2016
Croatian: Datum posljednje obnove odobrenja: 14. siječnja 2016.
English: Take the medicine pack with you, even if there are no tablets left.
Croatian: Ponesite sa sobom pakiranje lijeka, čak i ako u njemu nema više nijedne tablete.
English: Maximum daily dose
Croatian: Maksimalna dnevna doza
English: These medicinal products should not be administered simultaneously.
Croatian: Ti se lijekovi ne smiju primijeniti istodobno.
English: Doctor's telephone:
Croatian: Broj telefona liječnika:
English: Complete the following sections or ask your doctor to do it:
Croatian: Ispunite sljedeće dijelove ili zamolite liječnika da to učini:
English: Alu-PVC/PVdC blisters.
Croatian: Al-PVC/PVdC blisteri.
English: Data from clinical trials are only available for the Rotachrom
Croatian: Podaci iz kliničkih ispitivanja dostupni su samo za Rotachrom
English: Indication:
Croatian: Indikacija:
English: • Active clinically significant bleeding.
Croatian: • Aktivno, klinički značajno krvarenje.
English: Your doctor might change your anticoagulant treatment as follows:
Croatian: Liječnik Vam može promijeniti liječenje antikoagulansima na sljedeći način:
English: No systemic embolism events were reported.
Croatian: Nije prijavljen niti jedan događaj sistemske embolije.
English: If the bleeding does not stop on its own, seek medical attention immediately.
Croatian: • Ako krvarenje ne prestane samo od sebe, odmah zatražite medicinsku pomoć.
English: Eliquis can be given for three different medical conditions.
Croatian: Eliquis se može propisati za tri različita zdravstvena stanja.
English: * Dose adjusted population based on 2 of 3 dose reduction criteria in the ARISTOTLE study.
Croatian: * Populacija s prilagođenom dozom na temelju 2 od 3 kriterija smanjenja doze u ARISTOTLE ispitivanju.
English: Some medicines may increase the effects of Eliquis and some may decrease its effects.
Croatian: Neki lijekovi mogu pojačati učinke lijeka Eliquis, a neki drugi ih mogu umanjiti.
English: As per available medical guidelines, short duration of treatment (at least 3 months) should be based on transient risk factors (e.g., recent surgery, trauma, immobilisation).
Croatian: U skladu s dostupnim medicinskim smjernicama, kratko trajanje liječenja (najmanje 3 mjeseca) treba temeljiti na prolaznim čimbenicima rizika (primjerice, nedavni kirurški zahvat, trauma, imobilizacija).
English: Contact your doctor immediately if you experience any of these symptoms.
Croatian: Morate se odmah javiti svom liječniku ako dobijete bilo koji od navedenih simptoma.
English: Take Eliquis regularly as instructed.
Croatian: • Eliquis uzimajte redovito, prema uputama.
English: Eliquis helps to thin your blood.
Croatian: • Eliquis Vam pomaže razrijediti krv.
English: Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity.
Croatian: Ispitivanja na životinjama ne ukazuju na izravno ni neizravno štetno djelovanje u smislu reproduktivne toksičnosti.
English: Of these, 836 patients (33.7%) participated in the AMPLIFY study prior to enrollment in the AMPLIFY-EXT study.
Croatian: Od navedenih, 836 bolesnika (33,7%) sudjelovalo je u ispitivanju AMPLIFY prije uključenja u ispitivanje AMPLIFY-EXT.
English: AVERROES STUDY
Croatian: ISPITIVANJE AVERROES
English: Show this card to your pharmacist, dentist and any other healthcare professionals that treat you.
Croatian: Pokažite ovu karticu svom ljekarniku, stomatologu ili drugom zdravstvenom radniku koji Vas liječi.
English: Other medicines and Eliquis
Croatian: Drugi lijekovi i Eliquis
English: If you miss a dose, take it as soon as you remember and continue to follow your dosing schedule.
Croatian: Ako propustite jednu dozu, uzmite ju čim se sjetite i nastavite prema uobičajenom rasporedu uzimanja.
English: Doctor's Name:
Croatian: Ime i prezime liječnika:
English: • Lesion or condition if considered a significant risk factor for major bleeding.
Croatian: • Lezija ili stanje koje se smatra značajnim čimbenikom rizika za veliko krvarenje.
English: What Eliquis is and what it is used for
Croatian: Što je Eliquis i za što se koristi
English: • Swallow the mixture.
Croatian: • Progutajte mješavinu.
English: Birth Date:
Croatian: Datum rođenja:
English: ADVANCE-2 (knee)
Croatian: ADVANCE-2 (koljeno)
English: - Name: - Birth Date: - Indication: - Dose : ........mg twice daily - Doctor's Name: - Doctor's telephone:
Croatian: - Ime i prezime: - Datum rođenja: - Indikacija: - Doza: ........mg dvaput na dan - Ime i prezime liječnika: - Telefonski broj liječnika:
English: Fatal, n
Croatian: Smrtonosno, n
English: • hypertension
Croatian: • hipertenzija
English: • Recommended dosages and guidance on the posology for different indications
Croatian: • Preporučene doze i smjernice za doziranje za različite indikacije
English: What Eliquis is and what it is used for What you need to know before you take Eliquis How to take Eliquis
Croatian: Što je Eliquis i za što se koristi Što morate znati prije nego počnete uzimati Eliquis Kako uzimati Eliquis
English: The Marketing Authorisation Holder shall ensure that all physicians who are expected to prescribe apixaban are provided with the following educational material:
Croatian: Nositelj odobrenja će osigurati da svi liječnici za koje se očekuje da će propisivati apiksaban dobiju sljedeći edukacijski materijal:
English: However, since this may be due to a lower sensitivity of the non-clinical species compared to humans, this result should be interpreted with caution when extrapolating to humans.
Croatian: Ipak, budući da to može biti posljedica niže osjetljivosti životinjskih vrsta u pretkliničkim ispitivanjima u usporedbi s ljudima, kod ekstrapolacije na ljude ovaj rezultat treba interpretirati uz oprez.
English: Treatment of DVT or PE
Croatian: Liječenje DVT ili PE
English: AVERROES was stopped early based on a recommendation by the independent Data Monitoring Committee due to clear evidence of reduction of stroke and systemic embolism with an acceptable safety profile.
Croatian: Ispitivanje AVERROES prekinuto je rano na preporuku neovisnoga Odbora za praćenje podataka zbog jasnih dokaza o smanjenju broja slučajeva moždanog udara i sistemske embolije uz prihvatljiv profil sigurnosti.
English: What Eliquis looks like and contents of the pack
Croatian: Kako Eliquis izgleda i sadržaj pakiranja
English: Treatment with Eliquis does not require routine monitoring of exposure.
Croatian: • Liječenje lijekom Eliquis ne zahtijeva rutinsko praćenje izloženosti.
English: You should take the first tablet 12 to 24 hours after your operation.
Croatian: Prvu tabletu trebate uzeti 12 do 24 sata nakon operacije.
English: O-demethylation and hydroxylation at the 3-oxopiperidinyl moiety are the major sites of biotransformation.
Croatian: O-demetilacija i hidroksilacija na 3-oksopiperidinilskom dijelu glavna su mjesta biotransformacije.
English: This includes interventions for which the probability of clinically significant bleeding cannot be excluded or for which the risk of bleeding would be unacceptable.
Croatian: To uključuje intervencije kod kojih se ne može isključiti vjerojatnost klinički značajnog krvarenja ili kod kojih je rizik od krvarenja neprihvatljiv.
English: The PK/PD relationship observed in patients was consistent with that established in healthy subjects.
Croatian: PK/PD odnos zabilježen u bolesnika bio je konzistentan s onim opaženim u zdravih ispitanika.
English: Effect of apixaban on other medicinal products
Croatian: Učinak apiksabana na druge lijekove
English: The effects of Eliquis on pregnancy and the unborn child are not known.
Croatian: Učinci lijeka Eliquis na trudnoću i nerođeno dijete nisu poznati.
English: Surgery and invasive procedures
Croatian: Kirurški zahvati i invazivni postupci
English: Gender Exposure to apixaban was approximately 18% higher in females than in males.
Croatian: Spol Izloženost apiksabanu bila je otprilike 18% veća u žena nego u muškaraca.
English: • symptomatic heart failure (NYHA Class ≥ II)
Croatian: • simptomatsko zatajivanje srca (NYHA kategorija ≥ II)
English: In the event of haemorrhagic complications, treatment must be discontinued and the source of bleeding investigated.
Croatian: U slučaju hemoragijskih komplikacija, mora se prekinuti liječenje i istražiti uzrok krvarenja.
English: If neurological compromise is noted, urgent diagnosis and treatment is necessary.
Croatian: Ako se primijeti neurološko oštećenje, potrebna je hitna dijagnostička obrada i liječenje.
English: Please complete this section or ask your doctor to do it Name:
Croatian: Molimo Vas ispunite ovaj dio, ili zamolite svog liječnika da ga ispuni: Ime i prezime:
English: If you have difficulty swallowing the tablet whole, talk to your doctor about other ways to take Eliquis.
Croatian: Ako imate poteškoća s gutanjem cijele tablete, razgovarajte s liječnikom o drugim načinima uzimanja Eliquisa.
English: If surgery or invasive procedures cannot be delayed, appropriate caution should be exercised, taking into consideration an increased risk of bleeding.
Croatian: Ako se kirurški zahvat ili invazivni postupak ne mogu odgoditi, treba poduzeti odgovarajuće mjere opreza, uzevši u obzir povećani rizik od krvarenja.
English: This medicine helps to prevent blood clots from forming by blocking Factor Xa, which is an important component of blood clotting.
Croatian: Ovaj lijek pomaže u sprječavanju stvaranja krvnih ugrušaka blokiranjem faktora Xa, koji je važna komponenta zgrušavanja krvi.
English: Eliquis contains lactose (a type of sugar) and sodium
Croatian: Eliquis sadrži laktozu (jednu vrstu šećera) i natrij
English: It does not require antithrombin III for antithrombotic activity.
Croatian: Za antitrombotsku aktivnost ne iziskuje antitrombin III.
English: Lapses in therapy should be avoided and if anticoagulation with Eliquis must be temporarily discontinued for any reason, therapy should be restarted as soon as possible.
Croatian: Treba izbjegavati propuštanje doze, a ako se iz bilo kojeg razloga antikoagulacijska terapija lijekom Eliquis mora privremeno prekinuti, liječenje treba ponovno uvesti što je prije moguće.
English: Nonfatal DVT
Croatian: Nefatalni DVT
English: Eliquis is not recommended in children and adolescents under 18 years of age.
Croatian: Eliquis se ne preporučuje u djece i adolescenata mlađih od 18 godina.
English: Therapy should be continued long-term.
Croatian: Liječenje mora biti dugotrajno.
English: • Recommendations for dose adjustment in at risk populations, including renal or hepatic impairment patients
Croatian: • Preporuke za prilagodbu doze u rizičnim populacijama, uključujući bolesnike s oštećenom funkcijom bubrega ili jetre
English: • Details of populations potentially at higher risk of bleeding
Croatian: • Detalji o populacijama bolesnika koje mogu biti izložene povećanom riziku od krvarenja
English: Pharmacotherapeutic group: Antithrombotic agents, direct factor Xa inhibitors, ATC code: B01AF02
Croatian: Farmakoterapijska skupina: antitrombotici, direktni inhibitori faktora Xa, ATK oznaka: B01AF02
English: This includes interventions for which any bleeding that occurs is expected to be minimal, non-critical in its location or easily controlled.
Croatian: To uključuje intervencije kod kojih se očekuje minimalno krvarenje, krvarenje na mjestu koje nije kritično ili koje se lako može kontrolirati.
English: Your doctor will decide, if you should be treated with Eliquis when taking these medicines and how closely you should be monitored.
Croatian: Liječnik će odlučiti trebate li uzimati Eliquis kad uzimate te lijekove i odrediti koliko Vas pažljivo treba nadzirati.
English: AMPLIFY-EXT STUDY
Croatian: ISPITIVANJE AMPLIFY-EXT
English: Preclinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential, fertility and embryo-foetal development and juvenile toxicity.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti, kancerogenosti, plodnosti, embriofetalnog razvoja i juvenilne toksičnosti.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 18 May 2011
Croatian: Datum prvog odobrenja: 18. svibnja 2011.
English: If you need to have surgery or a procedure which may cause bleeding, your doctor might ask you to temporarily stop taking this medicine for a short while.
Croatian: Ako se morate podvrgnuti kirurškom zahvatu ili postupku koji može izazvati krvarenje, liječnik će možda zatražiti da nakratko prestanete uzimati ovaj lijek.
English: For preventing blood clots from re-occurring following completion of 6 months of treatment
Croatian: Za sprječavanje ponovnog nastanka krvnih ugrušaka nakon dovršetka 6-mjesečnog liječenja
English: Both apixaban and enoxaparin were given for 32-38 days in the ADVANCE-3 study and for 10-14 days in the ADVANCE-2 study.
Croatian: I apiksaban i enoksaparin su primjenjivani 32-38 dana u ispitivanju ADVANCE-3 te 10-14 dana u ispitivanju ADVANCE-2.
English: Table 2 System Organ Class
Croatian: Tablica 2 Klasifikacija organskog sustava
English: Hypotension (including procedural hypotension)
Croatian: Hipotenzija (uključujući hipotenziju tijekom zahvata)
English: Patients with active cancer
Croatian: Bolesnici s aktivnim rakom
English: If you are not sure whether a procedure may cause bleeding ask your doctor.
Croatian: Ako niste sigurni može li zahvat izazvati krvarenje, pitajte svog liječnika.
English: Swallow the tablet with a drink of water.
Croatian: Tabletu progutajte s vodom.
English: All treated n = 2,673
Croatian: Svi liječeni bolesnici n=2673
English: ARISTOTLE STUDY
Croatian: ISPITIVANJE ARISTOTLE
English: The signs, symptoms, and severity will vary according to the location and degree or extent of the bleeding (see sections 4.4 and 5.1).
Croatian: Znakovi, simptomi i težina variraju ovisno o mjestu i stupnju ili opsegu krvarenja (vidjeti dijelove 4.4 i 5.1).
English: Apixaban is not a significant inhibitor of P-gp.
Croatian: Apiksaban nije značajan inhibitor P-gp.
English: Indwelling epidural or intrathecal catheters must be removed at least 5 hours prior to the first dose of Eliquis.
Croatian: Trajni epiduralni ili intratekalni kateteri moraju se ukloniti barem 5 sati prije primjene prve doze lijeka Eliquis.
English: Do not stop taking Eliquis without talking to your doctor, as you are at risk of suffering from a stroke or other complications.
Croatian: • Nemojte prestati uzimati Eliquis bez razgovora s liječnikom, obzirom da imate rizik od moždanog udara ili drugih komplikacija.
English: Apixaban has multiple routes of elimination.
Croatian: Apiksaban se eliminira kroz nekoliko puteva.
English: Fold the card and keep it with you at all times
Croatian: Presavijte karticu i nosite je uvijek sa sobom
English: ASA was given at a once daily dose of 81 mg (64%), 162 (26.9%), 243 (2.1%), or 324 mg (6.6%) at the discretion of the investigator.
Croatian: ASK se davala jedanput na dan u dozi od 81 mg (64%), 162 mg (26,9%), 243 (2,1%) ili 324 mg (6,6%), prema odluci ispitivača.
English: What Eliquis contains
Croatian: Što Eliquis sadrži
English: • Crush the tablets with a pestle and mortar.
Croatian: • Zdrobite tablete pomoću tučka i mužara.
English: Eliquis contains the active substance apixaban and belongs to a group of medicines called anticoagulants.
Croatian: Eliquis sadrži djelatnu tvar apiksaban i pripada skupini lijekova koji se nazivaju antikoagulansima.
English: If you are not sure what to do or have missed more than one dose, ask your doctor, pharmacist or nurse.
Croatian: Ako niste sigurni što učiniti ili ako ste propustili više od jedne doze, obratite se svom liječniku, ljekarniku ili medicinskoj sestri.
English: The primary safety endpoint was major bleeding during the treatment period.
Croatian: Primarni sigurnosni ishod bilo je veliko krvarenje tijekom razdoblja liječenja.
English: Unchanged apixaban is the major drug-related component in human plasma with no active circulating metabolites present.
Croatian: Nepromijenjeni apiksaban najvažnija je komponenta lijeka u ljudskoj plazmi, u kojoj nema aktivnih cirkulirajućih metabolita.
English: However, there is no clinical experience with the use of 4-factor PCC products to reverse bleeding in individuals who have received Eliquis.
Croatian: Međutim, nema kliničkog iskustva s primjenom 4-faktorskih PCC proizvoda za zaustavljanje krvarenja u osoba koje su primile Eliquis.
English: Start treatment with the anticoagulant medicines (for example heparin) at the time you would have taken the next tablet.
Croatian: Počnite liječenje antikoagulansom (na primjer heparinom) u vrijeme kad biste uzeli sljedeću tabletu.
English: In rat milk, a high milk to maternal plasma ratio (Cmax about 8, AUC about 30) was found, possibly due to active transport into the milk.
Croatian: U mlijeku štakorica utvrđen je visok omjer lijeka u mlijeku u odnosu na majčinu plazmu (Cmax približno 8, AUC približno 30), što može biti posljedica aktivnog transporta u mlijeko.
English: Key Elements of the Prescriber Guide:
Croatian: Ključne informacije u vodiču za propisivača:
English: Take special care with Eliquis - if you know that you have a disease called antiphospholipid syndrome (a disorder of the immune system that causes an increased risk of blood clots), tell your doctor who will decide if the treatment may need to be changed.
Croatian: Budite posebno oprezni s lijekom Eliquis - ako znate da imate bolest koja se naziva antifosfolipidni sindrom (poremećaj imunološkog sustava koji uzrokuje povećani rizik od nastanka krvnih ugrušaka), obavijestite o tome svog liječnika koji će odlučiti postoji li potreba za izmjenom terapije.
English: If a dose is missed, the patient should take Eliquis immediately and then continue with twice daily intake as before.
Croatian: Ako propusti uzeti dozu, bolesnik odmah mora uzeti Eliquis i zatim nastaviti uzimati lijek dvaput na dan kao i prije.
English: Key secondary endpoints of major bleeding and all cause death were tested in a pre-specified hierarchical testing strategy to control the overall type 1 error in the trial.
Croatian: Ključne sekundarne mjere ishoda - veliko krvarenje i smrt zbog bilo kojega razloga, ispitane su prethodno utvrđenom strategijom hijerarhijskog testiranja da bi se u cijelosti mogla kontrolirati pojavnost pogreške tipa 1 u ispitivanju.
English: In the toxicity studies little to no increase of bleeding tendency was found.
Croatian: U ispitivanjima toksičnosti primijećeno je malo ili nikakvo povećanje sklonosti krvarenju.
English: This can cause the legs to swell, with or without pain.
Croatian: Zbog toga noge mogu oticati, pri čemu možete ili ne morate osjećati bol.
English: For all patients undergoing cardioversion, confirmation should be sought prior to cardioversion that the patient has taken apixaban as prescribed.
Croatian: U svih bolesnika koji će biti podvrgnuti kardioverziji, prije kardioverzije potrebno je zatražiti potvrdu da je bolesnik uzeo apiksaban kako je propisano.
English: Depending on local availability, a consultation of a coagulation expert should be considered in case of major bleedings.
Croatian: Ovisno o lokalnoj dostupnosti, u slučaju većih krvarenja potrebno je razmotriti konzultaciju sa stručnjakom za koagulaciju.
English: In the study, the incidence in major bleeding for both apixaban doses was not statistically different from placebo.
Croatian: U ispitivanju, incidencija u velikom krvarenju obje doze apiksabana nije se statistički razlikovala od placeba.