FrancophonIA/ELRC3.0 huggingface dataset:
English: Other effects consistent with the pharmacological activity of torasemide were observed in pre-clinical studies in healthy dogs at the recommended dose, i.e. dry mucosa of the oral cavity, reversible increases in glucose and aldosterone serum concentrations, decrease in urine specific gravity and increase in urine pH.
Croatian: Drugi učinci u skladu s djelovanjem torasemida primijećeni su u pretkliničkim ispitivanjima u zdravih pasa pri preporučenim dozama, tj. suha sluznica usne šupljine, reverzibilno povećanje koncentracija glukoze i aldosterona u serumu, smanjenje specifične težine urina i povećanje pH vrijednosti urina.
English: After administration to healthy dogs of 3 times and 5 times the maximum dose for 5 consecutive days followed by 177 daily administrations of 3 times and 5 times the highest therapeutic recommended dose for maintenance, histopathological changes in the kidneys (interstitial inflammation, dilatation of renal tubules and subscapular cysts) were noted in addition to the effects observed after the administration of the recommended dose (see section "Adverse reactions").
Croatian: Nakon primjene trostruko i peterostruko većih doza lijeka od maksimalne tijekom 5 uzastopnih dana na zdravim psima nakon čega je slijedila primjena tijekom 177 dana trostruko i peterostruko većih doza od maksimalne preporučene terapijske doze održavanja, primijećene su histopatološke promjene na bubrezima (intersticijska upala, dilatacija renalnih tubula i subskapularne ciste) osim učinaka primijećenih nakon primjene preporučene doze (vidi odjeljak "Nuspojave").
English: Renal function (measurement of blood urea and creatinine as well as urine protein: creatinine (UPC) ratio), hydration status and serum electrolytes status should be monitored prior to and during treatment at very regular intervals according to the benefit-risk assessment performed by the responsible veterinarian (see sections "Contraindications" and "Adverse reactions").
Croatian: Bubrežna funkcija (mjerenje ureje i kreatinina u krvi, kao i proteina u urinu: omjer proteina i kreatinina u urinu), status hidratacije i status elektrolita u serumu treba pratiti prije i tijekom liječenja u redovitim intervalima u skladu s procjenom koristi i rizika izvrši odgovorni veterinar (vidi odjeljke “Kontraindikacije“ i “Nuspojave“).
English: Manufacturer responsible for batch release: Ceva Santé Animale
Croatian: Proizvođač biološki djelatnih tvari i proizvođač odgovoran za puštanje serije u promet Ceva Santé Animale
English: In a clinical field study, renal insufficiency, a transient increase in renal blood parameters, haemoconcentration and alterations in electrolyte levels (chloride, sodium, potassium, phosphorus, magnesium, calcium) were very commonly observed.
Croatian: U kliničkoj terenskoj studiji vrlo su često primijećeni bubrežna insuficijencija, privremeno povišeni bubrežni parametri u krvi, hemokoncentracija i promjene razine elektrolita (klorida, natrija, kalija, fosfora, magnezija, kalcija).
English: In a clinical field study, renal insufficiency, an increase in renal blood parameters, haemoconcentration and alterations in electrolyte levels (chloride, sodium, potassium, phosphorus, magnesium, calcium) were very commonly observed.
Croatian: U kliničkoj terenskoj studiji vrlo su često primijećeni bubrežna insuficijencija, povišeni bubrežni parametri u krvi, hemokoncentracija i promjene razine elektrolita (klorida, natrija, kalija, fosfora, magnezija, kalcija).
English: Since the ascending limb of the loop of Henle is impermeable to water, the inhibition of Na and Cl movement from the lumen to the interstitial space increases the concentration of ions in the lumen and produces a hypertonic medullary interstitium.
Croatian: Na i Cl od lumena do međuprostora povećava koncentraciju iona u lumenu i proizvodi hipertonički medularni intersticij.
English: Co-administration of loop diuretics and NSAIDs can result in a decreased natriuretic response.
Croatian: Istovremena primjena diuretika Henleove petlje i nesteroidnih protuupalnih lijekova (NSPUL-a) može rezultirati smanjenom natriuretičkom reakcijom.
English: 30 chewable tablets 90 chewable tablets
Croatian: 90 tableta za žvakanje
English: Do not use in cases of renal failure.
Croatian: Ne primjenjivati u slučajevima zatajenja bubrega.
English: The safety and efficacy of the product has not been assessed for dogs weighing less than 2.5 kg. For these animals use only according to the benefit/risk assessment by the responsible veterinarian.
Croatian: Neškodljivost i učinkovitost proizvoda nije procijenjena za pse lakše od 2,5 kg.
English: 1 mg of torasemide
Croatian: 1 mg torasemida
English: Isemid 1 mg chewable tablets Isemid 2 mg chewable tablets Isemid 4 mg chewable tablets torasemide
Croatian: Isemid 4 mg, tablete za žvakanje torasemid
English: Name and address of the manufacturer(s) responsible for batch release
Croatian: Naziv i adresa proizvođača odgovornih za puštanje serije u promet
English: Store out of reach of animals.
Croatian: Čuvati izvan dohvata životinja.
English: Oblong brown scored tablets.
Croatian: Duguljasta smeđa tableta s razdjelnom linijom.
English: 6.6 Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Croatian: 6.6 Posebne mjere predostrožnosti za odlaganje neupotrebljenog veterinarsko-medicinskog proizvoda ili otpadnih materijala dobivenih primjenom tog proizvoda Bilo koji neupotrebljeni veterinarsko-medicinski proizvod ili otpadni materijali dobiveni primjenom tih veterinarsko-medicinskih proizvoda trebaju se odlagati u skladu s lokalnim propisima.
English: 2 mg of torasemide
Croatian: 2 mg torasemida
English: PACKAGE SIZE
Croatian: 15. OSTALE INFORMACIJE Veličine pakovanja
English: Number and strength of Isemid tablets to be administered Initial/Maintenance dose
Croatian: Broj i jačina tableta Isemida za primjenu Početna doza/doza održavanja (0,13 do 0,25 mg/kg/dnevno)
English: 4 mg of torasemide
Croatian: 4 mg torasemida
English: Isemid 1 mg chewable tablets for dogs (2.5-11.5 kg) Isemid 2 mg chewable tablets for dogs (> 11.5-23 kg) Isemid 4 mg chewable tablets for dogs (> 23-60 kg) torasemide
Croatian: Isemid 1 mg, tablete za žvakanje za pse (2,5-11,5 kg) Isemid 2 mg, tablete za žvakanje za pse (11,6-23 kg) Isemid 4 mg, tablete za žvakanje za pse (23,1-60 kg) torasemid
English: A. MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE
Croatian: PROIZVOĐAČI BIOLOŠKI DJELATNIH TVARI I PROIZVOĐAČI ODGOVORNI ZA PUŠTANJE SERIJE U PROMET
English: PACKAGE LEAFLET Isemid 1 mg chewable tablets for dogs (2.5-11.5 kg) Isemid 2 mg chewable tablets for dogs (> 11.5-23 kg) Isemid 4 mg chewable tablets for dogs (> 23-60 kg)
Croatian: NAZIV VETERINARSKO-MEDICINSKOG PROIZVODA Isemid 1 mg, tablete za žvakanje za pse (2,5-11,5 kg) Isemid 2 mg, tablete za žvakanje za pse (> 11,5-23 kg) Isemid 4 mg, tablete za žvakanje za pse (> 23-60 kg)
English: Isemid 1 mg chewable tablets for dogs (2.5-11.5 kg) Isemid 2 mg chewable tablets for dogs (> 11.5-23 kg) Isemid 4 mg chewable tablets for dogs (> 23-60 kg)
Croatian: UPUTA O VMP Isemid 1 mg, tablete za žvakanje za pse (2,5-11,5 kg) Isemid 2 mg, tablete za žvakanje za pse (11,6-23 kg) Isemid 4 mg, tablete za žvakanje za pse (23,1-60 kg)
English: The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)) - common (more than 1 but less than 10 animals in 100 animals treated) - uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
Croatian: Učestalost nuspojava je određena sukladno sljedećim pravilima: - vrlo česte (više od 1 na 10 tretiranih životinja pokazuju nuspojavu(e) )
English: Usually you will not experience any symptoms when these changes occur.
Croatian: Obično nećete osjećati nikakve simptome kada se ove promjene dogode.
English: The changes will completely resolve within a few weeks.
Croatian: Ove promjene potpuno će nestati za nekoliko tjedana.
English: This is always done by a pharmacist or a nurse and not by yourself.
Croatian: Ovo će uvijek učiniti ljekarnik ili medicinska sestra, a ne Vi sami.
English: Unopened bottle 3 years.
Croatian: Neotvorena boca 3 godine
English: Children and adolescents (< 18 years)
Croatian: Djeca i adolescenti (u dobi do 18 godina)
English: Not known (cannot be estimated from the available data).
Croatian: Nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Follow-up time was 28 days.
Croatian: Razdoblje praćenja iznosilo je 28 dana.
English: Distribution and biotransformation
Croatian: Distribucija i biotransformacija
English: Gliolan with food and drink
Croatian: Gliolan s hranom i pićem
English: • Pregnancy (see sections 4.6 and 5.3).
Croatian: • Trudnoća (vidjeti dio 4.6 i 5.3).
English: Do not use this medicine if you are pregnant.
Croatian: Nemojte uzimati ovaj lijek ako ste trudni.
English: Talk to your doctor or pharmacist before taking Gliolan.
Croatian: Obratite se svom liječniku ili ljekarniku prije nego uzmete Gliolan.
English: The safety and efficacy of Gliolan in children and adolescents aged 0 to 18 years have not yet been established.
Croatian: Sigurnost i djelotvornost Gliolana u djece i adolescenata u dobi od 0 do 18 godina nisu još ustanovljene.
English: Side effects are divided into the following two categories:
Croatian: Nuspojave se dijele u sljedeće dvije kategorije:
English: The pharmacist or nurse will calculate the exact dose you need and the amount of the solution (in ml) you have to drink.
Croatian: Ljekarnik ili medicinska sestra izračunat će točnu dozu koju trebate i količinu otopine (u ml) koju morate popiti.
English: Pack sizes: 1, 2 and 10 bottles.
Croatian: Veličina pakiranja: 1, 2 i 10 boca.
English: • in case of known or suspected pregnancy.
Croatian: • u slučaju trudnoće ili sumnje na trudnoću.
English: Tell your doctor immediately if you experience any complaints.
Croatian: Obavijestite svog liječnika odmah ako osjetite ikakve smetnje.
English: If you take more Gliolan than you should
Croatian: Ako uzmete više Gliolana nego što ste trebali
English: You should not drink or eat for at least 6 hours before anaesthesia.
Croatian: Ne smijete jesti niti piti najmanje 6 sati prije anestezije.
English: 5-ALA is eliminated quickly with a terminal half-life of 1-3 hours.
Croatian: 5-ALA se eliminira brzo, s poluvijekom od 1-3 sata.
English: You should not take any such products up to 2 weeks after you have taken Gliolan.
Croatian: Ovakve proizvode ne smijete uzimati do 2 tjedna nakon što ste uzeli Gliolan.
English: Other medicines and Gliolan
Croatian: Drugi lijekovi i Gliolan
English: In this case, this medicine should be used with caution because your blood pressure may be decreased.
Croatian: U tom slučaju ovaj lijek treba primjenjivati s oprezom jer može sniziti krvni tlak.
English: The training course will take place at qualified training centres using qualified trainers.
Croatian: Edukacijski tečaj će se održati u kvalificiranom centru za obuku pod vodstvom kvalificiranog nastavnog osoblja.
English: It is not known whether Gliolan will harm an unborn baby.
Croatian: Nije poznato može li Gliolan štetiti nerođenom djetetu.
English: • if you are allergic to 5-ALA or porphyrins.
Croatian: • ako ste alergični na 5-ALA ili porfirine
English: Light exposed skin recovered completely except for a persistent reduction in the number of hair follicles.
Croatian: Koža izložena svjetlu potpuno se oporavila, osim trajnog smanjenja broja folikula dlaka.
English: Therefore, Gliolan should not be used during pregnancy.
Croatian: Stoga se Gliolan ne smije primjenjivati tijekom trudnoće.
English: No significant increase in overall survival has been observed in this trial; however, it was not powered to detect such a difference.
Croatian: U ovom ispitivanju nije primijećeno povećano ukupno preživljenje, međutim, snaga ispitivanja nije bila dovoljna da bi se mogla ustanoviti takva razlika.
English: However, considering the therapeutic indication, a single oral treatment with 5-ALA might not be related to any serious potential carcinogenic risk.
Croatian: Međutim, uzimajući u obzir terapijsku indikaciju, jednokratna peroralna doza 5-ALA ne bi trebala biti povezana s ozbiljnim potencijalnim rizikom od kancerogenog djelovanja.
English: There is no experience with Gliolan in children and adolescents.
Croatian: Nema iskustava s primjenom Gliolana u djece i adolescenata.
English: It was stated that the patient had been exposed to more light than permitted for the trial.
Croatian: Ustanovljeno je da je bolesnik bio izložen svjetlu više nego li je to bilo dopušteno samim ispitivanjem.
English: What Gliolan is and what it is used for
Croatian: Što je Gliolan i za što se koristi
English: The powder is a white to off-white cake.
Croatian: Prašak je u obliku bijelog do gotovo bijelog kolačića.
English: In this case, anaesthesia and surgery must be postponed for at least 2 hours, if possible.
Croatian: U tom slučaju početak anestezije i operacija moraju biti odgođeni po mogućnosti barem za 2 sata.
English: Contrast-enhancing tumour was resected in 64 % of patients in the experimental group compared to 38 % in the controlgroup (p<0.0001).
Croatian: Uz pomoć kontrasta tumor je reseciran u 64 % bolesnika u eksperimentalnoj skupini, u usporedbi s 38 % u kontrolnoj skupini (p < 0,0001).
English: Keep the bottle in the outer carton in order to protect from light.
Croatian: Bocu čuvati u vanjskom pakiranju radi zaštite od svjetlosti.
English: What Gliolan is and what it is used for What you need to know before you take Gliolan How to take Gliolan
Croatian: Što je Gliolan i za što se koristi Što morate znati prije nego počnete uzimati Gliolan Kako uzimati Gliolan
English: Date of first authorisation: 07 September 2007 Date of latest renewal: 12 September 2012
Croatian: Datum posljednje obnove odobrenja: 12. rujna 2012.
English: • Acute or chronic types of porphyria.
Croatian: • Akutni ili kronični oblici porfirije.
English: What Gliolan looks like and contents of the pack
Croatian: Kako Gliolan izgleda i sadržaj pakiranja
English: Pharmacotherapeutic group: Antineoplastic agents, sensitisers used in photodynamic therapy, ATC code: L01XD04
Croatian: Farmakoterapijska skupina: Antineoplastici, senzibilizirajuća sredstva za primjenu u fotodinamičkoj terapiji, ATK oznaka: L01XD04
English: Therefore this medicine is not recommended in this age group.
Croatian: Stoga se ovaj lijek ne preporučuje u ovoj dobnoj skupini.
English: vomiting, nausea
Croatian: povraćanje, mučnina
English: Very rare side effects (may affect up to 1 in 10,000 people) or not known (frequency cannot be estimated from the available data):
Croatian: Vrlo rijetke nuspojave (mogu se pojaviti u do 1 na 10 000 osoba) ili nisu poznate (učestalost se ne može procijeniti iz dostupnih podataka):
English: Long-term in vivo carcinogenicity studies have not been conducted.
Croatian: Dugotrajna in vivo ispitivanja kancerogenosti nisu provedena.
English: This helps the surgeon to remove the tumour while sparing healthy tissue.
Croatian: Time se kirurgu pomaže ukloniti tumor uz poštedu zdravog tkiva.
English: • If you have a heart disease or had heart disease in the past, you should tell your doctor.
Croatian: • Bolujete li ili ste nekad bolovali od srčane bolesti, recite to svome liječniku.
English: The majority of genotoxicity studies performed in the dark do not reveal a genotoxic potential of 5-ALA.
Croatian: Većina ispitivanja genotoksičnosti provedenih u mraku ne upućuje na genotoksični potencijal 5-ALA.
English: The cardiovascular effects seen are considered to be related to the intravenous route of administration.
Croatian: Smatra se da su navedeni kardiovaskularni učinci povezani s intravenskim putem primjene.
English: Use of 5-ALA under conditions other than the ones used in the clinical trials entail an undetermined risk.
Croatian: Primjena 5-ALA u uvjetima drugačijim od onih u kliničkim ispitivanjima nosi sa sobom izvjesni rizik.
English: Follow-up time comprised at least 180 days after administration.
Croatian: Razdoblje praćenja uključivalo je najmanje 180 dana nakon primjene lijeka.
English: If you have forgotten to take this medicine during this time period, it is not advisable to take it just before start of anaesthesia.
Croatian: Ako ste zaboravili uzeti ovaj lijek u to vrijeme, ne savjetuje se uzeti lijek neposredno prije početka anestezije.
English: A positive predictive value of tissue fluorescence of 84.8 % (90 % CI: 70.7 %-93.8 %) was found.
Croatian: Utvrđena je i pozitivna prediktivna vrijednost fluorescencije tkiva od 84,8 % (90 % CI: 70,7 %-93,8 %).
English: − A training course for neurosurgeons which is aimed at risk minimisation and to support safe and effective use for the medicinal product.
Croatian: Edukacijski tečaj za neurokirurge kojemu je cilj minimalizacija rizika i osiguranje sigurne i učinkovite primjene ovog lijeka.
English: This medicine is a powder that must be first mixed with drinking water before use.
Croatian: Ovaj je lijek u obliku praška koji se prije uzimanja mora pomiješati s vodom za piće.
English: Accordingly, general light protective measures of eyes and skin are recommended for at least 24 hours after administration of this medicinal product.
Croatian: U skladu s ovime, preporučuju se opće mjere zaštite od svjetla za oči i kožu tijekom najmanje 24 sata nakon primjene ovog lijeka.
English: Gliolan is provided in a glass bottle and presented in packs of 1, 2 and 10 bottles.
Croatian: Gliolan dolazi u staklenoj boci u pakiranjima od 1, 2 i 10 boca.
English: Respiratory insufficiency and erythema completely resolved.
Croatian: Respiratorna insuficijencija i eritrem u potpunosti su se povukli.
English: The positive predictive value of strong fluorescence was higher (100.0 %; 90 % CI: 91.1 %-100.0 %) than of weak fluorescence (83.3 %; 90 % CI: 68.1 %-93.2 %).
Croatian: Pozitivna prediktivna vrijednost jake fluorescencije bila je veća (100,0 %; 90 % CI: 91,1 %-100,0 %) nego slabe fluorescencije (83,3 %; 90 % CI: 68,1 %-93,2 %).
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, particularly medicines that may cause skin problems when the skin comes under strong light (for example some types of medicines called antibiotics), but also medicines obtained without prescription (for example hypericin or Saint John's wort extracts).
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove, osobito lijekove koji mogu izazvati kožne probleme nakon što se ona izloži jakom svjetlu (npr. neki antibiotici), ali i lijekove nabavljene bez liječničkog recepta (npr. hipericin odnosno ekstrakt gospine trave).
English: Five minutes after administration, the baseline values had been reached again.
Croatian: Pet minuta nakon primjene lijeka ponovno su se uspostavile početne vrijednosti.
English: PPIX plasma levels rapidly decline during the subsequent 20 hours and are not detectable anymore 48 hours after administration.
Croatian: Razina PPIX u plazmi brzo opada idućih 20 sati i nakon 48 sati njegova se prisutnost više ne može utvrditi.
English: Fertility There are no data available regarding the influence of 5-ALA on fertility.
Croatian: Plodnost Nema dostupnih podataka o utjecaju 5-ALA na plodnost.
English: It is not known whether this medicine enters breast milk.
Croatian: Nije poznato izlučuje li se ovaj lijek u majčino mlijeko.
English: These changes peak between 7 and 14 days after surgery.
Croatian: Ove promjene najizraženije su između 7 i 14 dana nakon operacije.
English: An adverse drug reaction of mild nausea was reported in 1 out of 21 volunteers.
Croatian: Nuspojava na lijek u obliku blage mučnine pojavila se u jednog od 21 dobrovoljca.
English: In the presence of visible light, fluorescence of PPIX (photodynamic effect) in certain target tissues can be used for photodynamic diagnosis.
Croatian: U prisutnosti vidljivog svjetla fluorescencija PPIX-a (fotodinamički učinak) u određenim ciljnim tkivima može se koristiti za fotodinamičku dijagnostiku.
English: The difference was statistically significant using the chi-square test (p=0.015).
Croatian: Hi-kvadrat test pokazao je statistički značajnu razliku (p = 0,015).
English: Plasma protein binding of 5-ALA is unknown.
Croatian: Vezivanje 5-ALA za proteine plazme nije poznato.
English: This medicine is generally used once only, namely 2-4 hours before anaesthesia for surgery for certain brain tumours called glioma.
Croatian: Ovaj se lijek općenito primjenjuje samo jedanput, i to 2-4 sata prije uvođenja u anesteziju radi operacije određenih moždanih tumora koji se zovu gliomi.
English: If you forget to take Gliolan
Croatian: Ako ste zaboravili uzeti Gliolan
English: If you have taken more Gliolan than you should, your doctor will decide on any necessary measures to avoid any problems, including sufficient protection from strong light (for example direct sunlight).
Croatian: Ako ste uzeli više Gliolana nego što ste trebali, Vaš će liječnik odlučiti o potrebnim mjerama za izbjegavanje mogućih posljedica, uključujući zadovoljavajuću zaštitu od jakog svjetla (npr. izravnog sunčevog svjetla).
English: At the visit six months after tumour resection, 20.5 % of 5-ALA-treated-patients and 11 % of patients who underwent standard surgery were alive at the six-month visit without progression.
Croatian: Na kontrolnom pregledu 6 mjeseci nakon resekcije tumora, 20,5 % bolesnika koji su primili 5-ALA i 11 % bolesnika podvrgnutih standardnom kirurškom postupku preživjelo je šestomjesečno razdoblje bez progresije bolesti.
English: Another patient accidentally received an overdose of the medicinal product (3000 mg instead of 1580 mg).
Croatian: Jedan je bolesnik slučajno primio preveliku dozu lijeka (3000 mg umjesto 1580 mg).
English: photosensitivity reaction, photodermatosis
Croatian: Manje često: fotosenzitivna reakcija, fotodermatoza
English: This medicine itself has no influence on the ability to drive and use machines.
Croatian: Ovaj lijek sam po sebi ne utječe na sposobnost upravljanja vozilima i strojevima.
English: Uncommon (≥1/1,000 to <1/100) Rare (≥1/10,000 to <1/1,000) Very rare (<1/10,000)
Croatian: Manje često (≥ 1/1000 i < 1/100) Rijetko (≥ 1/10 000 i < 1/1000) Vrlo rijetko (< 1/10 000)
English: If the anaesthesia/surgery is delayed by some hours, additional doses of this medicine must not be given.
Croatian: Ako je početak anestezije/operacije pomaknut za nekoliko sati, ne smiju se dati dodatne doze ovog lijeka.
English: Therefore, resection of fluorescing tissue should be weighed up carefully against the neurological function of fluorescing tissue.
Croatian: Stoga resekcija fluorescirajućeg tkiva treba biti pažljivo odmjerena naspram neurološke funkcije fluorescirajućeg tkiva.
English: Tissue surrounding the tumour and normal brain may also be affected.
Croatian: Tkivo koje okružuje tumor i zdravo moždano tkivo također mogu biti zahvaćeni.
English: Therefore, this medicine should be used with caution in such patients.
Croatian: Stoga ovaj lijek treba primjenjivati s oprezom u takvih bolesnika.
English: This course shall consist of measures aiming to minimise adverse events associated with the Gliolan-fluorescence-guided surgery (in particular neurological serious adverse events) through adequate education about:
Croatian: Ovaj tečaj sastojat će se od usvajanja mjera kojima je cilj minimalizacija štetnih događaja povezanih s kirurškim postupkom uz pomoć Gliolanom izazvane fluorescencije (posebice ozbiljnih neuroloških štetnih događaja) putem odgovarajuće edukacije iz:
English: A safe distance to eloquent cortical areas and subcortical structures of at least 1 cm should be maintained independent of the degree of fluorescence.
Croatian: Potrebno je zadržati najmanje 1 cm sigurne udaljenosti od elokventnih kortikalnih područja i subkortikalnih struktura bez obzira na stupanj fluorescencije.
English: Adverse reactions observed after the use of this medicinal product for fluorescence-guided glioma resection are divided into the following two categories:
Croatian: Nuspojave primijećene nakon primjene ovog lijeka radi resekcije glioma uz pomoć fluorescencije dijele se u sljedeće dvije kategorije: