FrancophonIA/ELRC3.0 huggingface dataset:
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu/.
Danish: Du kan finde yderligere information om SOMAC Control på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu/.
English: See ‘Other medicines and SOMAC Control'.
Danish: Se brug af andet medicin sammen med SOMAC Control.
English: Do not take SOMAC Control tablets for more than 4 weeks without consulting your doctor.
Danish: Tag ikke SOMAC Control -tabletter i mere end 4 uger uden at kontakte lægen.
English: What you need to know before you take SOMAC Control
Danish: Det skal du vide, før du begynder at tage SOMAC Control
English: Tell your doctor immediately, before or after taking this medicine, if you notice any of the following symptoms, which could be a sign of another, more serious, disease: - an unintentional loss of weight (not related to a diet or an exercise programme) - vomiting, particularly if repeated - vomiting blood; this may appear as dark coffee grounds in your vomit - you notice blood in your stools; which may be black or tarry in appearance - difficulty in swallowing or pain when swallowing - you look pale and feel weak (anaemia) - chest pain - stomach pain - severe and/or persistent diarrhoea, because this medicine has been associated with a small increase in infectious diarrhoea.
Danish: Fortæl det straks til lægen før eller efter du har taget medicinen, hvis du oplever nogle af følgende symptomer, som kan være et tegn på en anden, mere alvorlig, sygdom: - uventet vægttab (som ikke er relateret til diæt eller et motionsprogram) - opkastning, især ved gentagelse - blodigt opkast, dette kan ses som mørkt kaffegrums i dit opkast - du opdager blodig afføring, som kan være sort eller tjærefarvet - synkebesvær eller smerte i forbindelse med synkning - du ser bleg ud eller føler dig sløj (blodmangel) - brystsmerter - mavesmerter - kraftig og/eller vedvarende diaré, da dette lægemiddel er forbundet med en let øget risiko for infektiøs diaré - hvis du får udslæt, især på de dele af huden, der er udsat for sol, skal du snarest sige det til lægen,
English: SOMAC Control'.
Danish: ”SOMAC Control indeholder”).
English: Rash / exanthema / eruption;
Danish: Udslæt/eksant em/ eruptioner, Kløe
English: SOMAC Control is used for the short-term treatment of reflux symptoms (for example heartburn, acid regurgitation) in adults.
Danish: SOMAC Control bruges til korttidsbehandling af reflukssymptomer (f.eks. halsbrand og sure opstød) hos voksne.
English: What SOMAC Control looks like and contents of the pack The gastro-resistant tablets are yellow, oval, biconvex film-coated tablets imprinted with “P20” on one side.
Danish: Enterotabletterne er gule, ovale, bikonvekse filmovertrukne tabletter præget med ”P20” på den ene side.
English: If you take more SOMAC Control than you should Tell your doctor or pharmacist if you have taken more than the recommended dose.
Danish: Fortæl det til lægen eller apoteket hvis du har taget mere end den anbefalede dosis.
English: What SOMAC Control is and what it is used for What you need to know before you take SOMAC Control How to take SOMAC Control Possible side effects
Danish: Det skal du vide, før du begynder at tage SOMAC Control Sådan skal du tage SOMAC Control Bivirkninger
English: SOMAC Control 20 mg gastro-resistant tablets Pantoprazole
Danish: SOMAC Control 20 mg enterotabletter Pantoprazol
English: SOMAC Control is indicated for short-term treatment of reflux symptoms (e.g. heartburn, acid regurgitation) in adults.
Danish: SOMAC Control er indiceret til korttidsbehandling af reflukssymptomer (fx halsbrand, syreregurgitation) hos voksne.
English: Do not take SOMAC Control: - if you are allergic to pantoprazole or to any of the other ingredients of this medicine (listed in section 6) - if you are taking HIV protease inhibitors such as atazanavir, nelfinavir (for the treatment of
Danish: Tag ikke SOMAC Control: - hvis du er allergisk over for pantoprazol eller et af de øvrige indholdsstoffer (angivet i afsnit 6
English: Talk to your doctor before taking SOMAC Control - if you have been treated for heartburn or indigestion continuously for 4 or more weeks - if you are over 55 years old and taking non-prescription indigestion treatment on a daily basis - if you are over 55 years old with any new or recently changed reflux symptoms - if you have previously had a gastric ulcer or stomach surgery - if you have liver problems or jaundice (yellowing of skin or eyes) - if you regularly see your doctor for serious complaints or conditions - if you are due to have an endoscopy or a breath test called a C-urea test. - if you have ever had a skin reaction after treatment with a medicine similar to SOMAC Control that reduces stomach acid.
Danish: Kontakt din læge, før du tager SOMAC Control - hvis du er blevet behandlet for halsbrand eller fordøjelsesbesvær uafbrudt i mere end 4 uger - hvis du er over 55 år og daglig tager medicin uden recept mod fordøjelsesbesvær
English: How to take SOMAC Control
Danish: Sådan skal du tage SOMAC Control
English: SOMAC Control 20 mg gastro-resistant tablets
Danish: SOMAC Control 20 mg, enterotabletter
English: Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.
Danish: Brug af anden medicin sammen med SOMAC Control Fortæl det til lægen eller apoteket, hvis du tager, har taget eller overvejer at tage andet medicin.
English: Takeda Italia S.p.A. Tel: +3906502601
Danish: Tel: +3906502601
English: The MAHs should identify a specific patient population for which the benefits of the product outweigh the risk.
Danish: Indehaverne af markedsføringstilladelse udpeger en konkret patientpopulation, hos hvem fordelene ved produktet overstiger risikoen.
English: National Competent Authorities of Member State(s) or Reference Member State(s) if applicable shall ensure that the following conditions are fulfilled by the MAH(s):
Danish: De nationale kompetente myndigheder i medlemsstaten (-staterne) eller i givet fald i referencemedlemsstaten (-staterne) sikrer, at indehaveren (indehaverne) af markedsføringstilladelse opfylder følgende betingelser:
English: Rehydration may be necessary.
Danish: Rehydrering kan vise sig nødvendig.
English: Meat and offal: 13 days.
Danish: Kød og indmad: 13 dage.
English: Batch {number}
Danish: <Batch> {nummer}
English: Date of first authorisation: 13/12/2016
Danish: Dato for første markedsføringstilladelse: 13/12/2016
English: The active substance in HALAGON is an allowed substance as described in table 1 of the annex to Commission Regulation (EU) No 37/2010:
Danish: Det aktive stof i HALAGON er et tilladt stof som beskrevet i tabel 1 i bilaget til Kommissionens forordning (EU) nr. 37/2010:
English: The product should not enter watercourses as this may be dangerous for fish and other aquatic organisms.
Danish: Produktet må ikke udledes i vandløb, da dette kan være farligt for fisk og andre organismer i vandet.
English: Repetitive contact with the product may lead to skin allergies.
Danish: Gentagen kontakt med produktet kan medføre hudallergier.
English: An appropriate device for oral administration is included.
Danish: En passende anordning til oral administration medfølger.
English: Administration should start within 24 hours after the onset of diarrhoea.
Danish: Administrationen skal starte inden for 24 timer efter starten af diarréen.
English: In case of skin and eye contact wash the exposed area thoroughly with clean water.
Danish: I tilfælde af hud- og øjenkontakt skylles det berørte område grundigt med rent vand.
English: The excipients listed in section 6.1 of the SPC are either allowed substances for which table 1 of the annex to Commission Regulation (EU) No 37/2010 indicates that no MRLs are required or are considered as not falling within the scope of Regulation (EC) No 470/2009 when used as in this product.
Danish: Hjælpestofferne anført under punkt 6.1 i produktresuméet er enten tilladte hjælpestoffer, hvor tabel 1 i bilaget til Kommissionens forordning (EU) Nr. 37/2010 indikerer, at MRL-værdier ikke er påkrævet eller ikke anses for at være omfattet af forordning (EF) nr. 470/2009, når de anvendes i dette produkt.
English: Administration should start in the first 24 to 48 hours of age.
Danish: Administration skal starte i de første 24 til 48 timer efter fødslen.
English: Do not use in case of diarrhoea established for more than 24 hours and in weak animals.
Danish: Må ikke bruges i tilfælde af diarré, som er startet for mere end 24 timer siden, og til svage dyr.
English: 3) If the metering pump is used for the first time (or hasn't been used for a few days), carefully pump till a drop of solution is formed on top of the nozzle.
Danish: 3) Hvis doseringspumpen anvendes for første gang (eller ikke er blevet brugt i et par dage), pumpes der forsigtigt, indtil der dannes en dråbe af opløsningen på toppen af dysen.
English: The concentrations to inhibit 50% and 90% of the parasites, in an in vitro test system, are IC50 < 0.1 μg/ml and IC90 of 4.5
Danish: Den koncentration, der skal til for at dræbe henholdsvis 50 % og 90 % af parasitterne i et in vitro testsystem er IC50 < 0,1 µg/ml og IC90 på 4,5 µg/ml.
English: Wear protective gloves while handling the product.
Danish: Brug beskyttelseshandsker ved håndtering af præparatet.
English: In very rare cases, an increase in the level of diarrhoea has been observed in treated animals.
Danish: I meget sjældne tilfælde er der set en øgning af graden af diarré hos behandlede dyr.
English: Keep the bottle in the outer carton in order to protect from light.
Danish: Opbevar flasken i yderemballagen for at beskytte indholdet mod lys.
English: Not for use in animals from which milk is produced for human consumption
Danish: Må ikke anvendes til dyr, hvis mælk anvendes til konsum
English: The bioavailability of the drug in the calf following single oral administration is about 80%.
Danish: Biotilgængeligheden af lægemidlet i kalve efter en enkel oral indgift er ca. 80%.
English: 1) Screw the metering pump on the bottle.
Danish: 1) Skru doseringspumpen på flasken.
English: Halofuginone lactate is a salt whose antiprotozoal properties and efficacy against Cryptosporidium parvum have been demonstrated both in in vitro conditions and in artificial and natural infections.
Danish: Halofuginonlactat er et salt hvis antiprotozo-egenskaber og effekt mod Cryptosporidium parvum er blevet demonstreret både in vitro og ved kunstige og naturlige infektioner.
English: STATEMENT OF ACTIVE SUBSTANCE (S) AND OTHER INGREDIENTS
Danish: ANGIVELSE AF DE(T) AKTIVE STOF(FER) OG ANDRE INDHOLDSSTOFFER
English: The plasmatic concentrations of halofuginone after repeated oral administrations are comparable to the pharmacokinetic pattern after single oral treatment.
Danish: Plasmakoncentrationen af halofuginone er efter gentagen oral indgift sammenlignelig med det farmakokinetiske mønster efter enkel oral behandling.
English: Unchanged halofuginone is the major component in the tissues.
Danish: Uomdannet halofuginone er hovedkomponenten i vævene.
English: The active substance, halofuginone, is an antiprotozoal agent of the quinazolinone derivatives group (nitrogenous polyheterocycles).
Danish: Det aktive stof, halofuginone, er et antiprotozomiddel af quinazolinon derivatgruppen (nitrogenous polyheterocycles).
English: Clear yellow oral solution.
Danish: Klar gul oral opløsning.
English: Pull twice or three times, respectively, for administration of the desired volume (8 ml for calves of 35 - 45 kg and 12 ml for calves of 45 - 60 kg, respectively).
Danish: Træk to henholdsvis tre gange for at indgive den ønskede mængde (8 ml for kalve på 35-45 kg og 12 ml for kalve på 45-60 kg).
English: For oral use Read the package leaflet before use.
Danish: Til oral anvendelse Læs indlægssedlen før brug.
English: 0.03 mg For the full list of excipients, see section 6.1.
Danish: 0,03 mg Se afsnit 6.1 for en fuldstændig fortegnelse over hjælpestoffer.
English: Manufacturer responsible for batch release: Divasa-Farmavic, S.A.
Danish: Fremstiller ansvarlig for batchfrigivelse: Divasa-Farmavic, S.A.
English: 5) Pull the trigger of the metering pump completely for release of a dose that equals 4 ml of solution.
Danish: 5) Tryk stemplet i doseringspumpen helt ind for at udløse en dosis på 4 ml opløsning.
English: Pharmacotherapeutic group: Other antiprotozoal agents, halofuginone.
Danish: Farmakoterapeutisk gruppe: Andre antiprotozomidler, halofuginone.
English: Tartrazine (E102)
Danish: Tartrazin (E102)
English: The compound has a cryptosporidiostatic effect on Cryptosporidium parvum.
Danish: Produktet har en cryptosporidiostatisk effekt på Cryptosporidium parvum.
English: Symptoms of toxicity include diarrhoea, visible blood in faeces, decline in milk consumption, dehydration, apathy and prostration.
Danish: Symptomer på forgiftning er diarré, synligt blod i afføringen, nedsat mælkeindtag, dehydrering, apati og udmattelse.
English: • Reduction of diarrhoea due to diagnosed Cryptosporidium parvum infection.
Danish: • Reduktion af diarré forårsaget af diagnosticeret Cryptosporidium parvum-infektion.
English: Each bottle is sealed with a polypropylene cap. Each package also contains a 4 ml metering pump that consists of several components made out of high, low and linear low density polyethylene, polypropylene, stainless steel and silicone.
Danish: Hver pakke indeholder også en doseringspumpe til doser a 4 ml, som består af flere enkeltdele fremstillet af LDPE, HDPE, LLDPE, polypropylen, rustfrit stål og silicone.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE Outer carton
Danish: OPLYSNINGER, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE Karton
English: To ensure a correct dosage, an appropriate metering pump for administration of ‘HALAGON' is included.
Danish: For at sikre korrekt dosering medfølger en egnet doseringspumpe til indgivelse af HALAGON.
English: 4) Restrain the calf and insert the nozzle of the metering pump into the calves mouth.
Danish: 4) Hold kalven fast og før doseringspumpens dyse ind i kalvens mund.
English: However, in order to make the HALAGON treatment easier, a simplified dosage scheme is proposed:
Danish: For at gøre doseringen lettere foreslås følgende doseringsskema:
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals: People with known hypersensitivity to the active substance or any of the excipients should administer the veterinary medicinal product with caution.
Danish: Særlige forsigtighedsregler for personer, som indgiver lægemidlet til dyr: Personer med kendt overfølsomhed over for det aktive stof eller et af hjælpestofferne bør administrere veterinærlægemidlet med forsigtighed.
English: 0.50 mg Equivalent to 0.6086 mg of halofuginone lactate
Danish: 0,50 mg Svarende til 0,6086 mg halofuginonelaktat
English: Antiparasitic agents/Agents acting against protozoa
Danish: Antiparasitær e lægemidler / Midler mod protozer
English: Cattle (newborn calves)
Danish: Kvæg (nyfødte kalve)
English: Avoid skin, eye or mucosal contact with the product.
Danish: Undgå at produktet kommer i kontakt med hud, øjne og slimhinder.
English: 08503 Gurb-Vic, Barcelona Spain
Danish: 08503 Gurb-Vic, Barcelona Spanien
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals People with known hypersensitivity to the active substance or any of the excipients should administer the veterinary medicinal product with caution.
Danish: Særlige forsigtighedsregler for personer, som indgiver lægemidlet til dyr Personer med kendt overfølsomhed over for det aktive stof eller et af hjælpestofferne bør administrere veterinærlægemidlet med forsigtighed.
English: • 35 kg < calves ≤ 45 kg: 8 ml of HALAGON once a day during 7 consecutive days
Danish: • 35 kg < kalve ≤ 45 kg: 8 ml HALAGON én gang dagligt i 7 på hinanden følgende dage
English: Benzoic acid (E210)
Danish: Benzoesyre (E210)
English: To be supplied only on veterinary prescription.
Danish: Udleveres kun efter veterinærrecept.
English: In new-born calves:
Danish: Hos nyfødte kalve:
English: 71 08503 Gurb-Vic, Barcelona Spain
Danish: 71 08503 Gurb-Vic, Barcelona Spanien
English: The dosage is: 100 μg of halofuginone / kg bw / once a day for 7 consecutive days, i.e. 4 ml of HALAGON / 20 kg bw / once a day for 7 consecutive days.
Danish: Dosering er: 100 µg halofuginone / kg legemsvægt / 1 gang dagligt i 7 på hinanden følgende dage, svarende til 4 ml HALAGON / 20 kg legemsvægt / 1 gang dagligt i 7 på hinanden følgende dage.
English: • Prevention of diarrhoea due to diagnosed Cryptosporidium parvum infection, in farms with history of cryptosporidiosis.
Danish: • Forebyggelse af diarré forårsaget af diagnosticeret Cryptosporidium parvum-infektion i besætninger, der har haft cryptosporidiosis.
English: Administer after colostrum feeding, or after milk or milk replacer feeding only.
Danish: Må kun indgives efter fodring med kolostrum, mælk eller mælkeerstatning.
English: Benzoic acid (E210) Lactic acid (E270) Tartrazine (E102) Water, Purified
Danish: Benzoesyre (E210) Mælkesyre (E270) Tartrazin (E102)
English: For treatment of anorexic calves, the product should be administered in half a litre of an electrolyte solution.
Danish: Hos kalve, som ikke spiser, bør produktet indgives sammen med en halv liter elektrolytopløsning.
English: EMDOKA bvba J. Lijsenstraat 16 B-2321 Hoogstraten Belgium
Danish: EMDOKA bvba J. Lijsenstraat 16 B-2321 Hoogstraten Belgien
English: 2) Remove the protector cap from the nozzle.
Danish: 2) Fjern beskyttelseshætten fra dysen.
English: EMDOKA bvba John Lijsenstraat 16 B-2321 Hoogstraten Belgium
Danish: EMDOKA bvba John Lijsenstraat 16 B-2321 Hoogstraten Belgien
English: SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCTS OR WASTE MATERIALS, IF ANY
Danish: EVENTUELLE SÆRLIGE FORHOLDSREGLER VED BORTSKAFFELSE AF UBRUGTE PRODUKTER ELLER AFFALD FRA SÅDANNE, OM NØDVENDIGT
English: Shelf-life after first opening the container: 6 months.
Danish: Opbevaringstid efter første åbning af den indre emballage: 6 måneder.
English: Bovine 10 μg/kg 25 μg/kg
Danish: 25 μg/kg 30 μg/kg 30 μg/kg
English: Once broached, use by …
Danish: Efter første anvendelse anvendes resten inden …
English: Halofuginone (as lactate salt)
Danish: Halofuginone (som laktatsalt)
English: Halofuginone
Danish: Halofuginone (laktatsalt)
English: Cardboard box containing one bottle (high-density polyethylene) of 290 ml, 490 ml or 980 ml of the oral solution.
Danish: Karton indeholdende én flaske (HDPE) med 290 ml, 490 ml eller 980 ml oral opløsning.
English: Veterinary medicinal product subject to prescription.
Danish: Veterinærlægemiddel, der kun udleveres efter recept.
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGE Bottle of 290ml, 490 ml or 980 ml
Danish: OPLYSNINGER, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE Flaske indeholdende 290 ml, 490 ml eller 980 ml
English: 6) Put the protector cap back on the nozzle.
Danish: 6) Sæt beskyttelseshætten på dysen igen.
English: Shelf-life of the veterinary medicinal product as packaged for sale: 3 years Shelf-life after first opening the immediate packaging: 6 months.
Danish: Opbevaringstid for veterinærlægemidlet i salgspakning: 3 år.
English: Cardboard box with high density polyethylene bottles of 290 ml, 490 and 980 ml.
Danish: Karton med HDPE-flasker indeholdende 290 ml, 490 ml og 980 ml.
English: HALAGON 0.5 mg/ml oral solution for calves halofuginone (as lactate salt)
Danish: HALAGON 0,5 mg/ml oral opløsning til kalve halofuginone (som laktatsalt)
English: Do not use this veterinary medicinal product after the expiry date which is stated on the label after EXP. Shelf-life after first opening the immediate packaging: 6 months.
Danish: Brug ikke dette veterinærlægemiddel efter den udløbsdato, der står på etiketten.
English: HALAGON 0.5 mg/ml oral solution halofuginone
Danish: HALAGON 0,5 mg/ml, oral opløsning halufuginone
English: Pharmacokinetic particulars
Danish: 5.2 Farmakokinetiske egenskaber
English: Animal species MRLs
Danish: MRL Målvæv Andre bestemmelser
English: HALAGON 0.5 mg/ml oral solution for calves
Danish: HALAGON 0,5 mg/ml, oral opløsning til kalve
English: • 45 kg < calves < 60 kg: 12 ml of HALAGON once a day during 7 consecutive days
Danish: • 45 kg < kalve < 60 kg: 12 ml HALAGON én gang dagligt i 7 på hinanden følgende dage Ved mindre eller højere legemsvægt skal en præcis beregning foretages (4 ml/20 kg).
English: Marketing Authorisation Holder: EMDOKA bvba John Lijsenstraat 16
Danish: Indehaver af markedsføringstilladelsen: EMDOKA bvba
English: DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION
Danish: DOSERING FOR HVER DYREART,
English: It is taken morning and evening.
Danish: Det tages morgen og aften.
English: Stayveer received a marketing authorisation valid throughout the EU on 24 June 2013.
Danish: Stayveer fik en markedsføringstilladelse med gyldighed i hele EU den 24. juni 2013.
English: Further information on Stayveer can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Danish: Yderligere information om Stayveer findes på agenturets websted under: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: This medicine is the same as Tracleer, which is already authorised in the EU.
Danish: Lægemidlet er identisk med Tracleer, som allerede er godkendt i EU.
English: As for all medicines, data on the use of Stayveer are continuously monitored.
Danish: Som for alle lægemidler bliver data vedrørende brug af Stayveer løbende overvåget.
English: Other information about Stayveer
Danish: Andre oplysninger om Stayveer
English: The company that makes Tracleer has agreed that its scientific data can be used for Stayveer (‘informed consent').
Danish: Virksomheden, der fremstiller Tracleer, har indvilget i, at dens videnskabelige oplysninger må anvendes for Stayveer ("informeret samtykke").
English: Stayveer is available as film-coated tablets (62.5 mg and 125 mg).
Danish: Stayveer fås som filmovertrukne tabletter (62,5 mg og 125 mg).
English: What measures are being taken to ensure the safe and effective use of Stayveer?
Danish: Hvilke foranstaltninger træffes der for at sikre risikofri og effektiv anvendelse af Stayveer?
English: An overview of Stayveer and why it is authorised in the EU
Danish: En oversigt over Stayveer, og hvorfor det er godkendt i EU
English: The European Medicines Agency decided that Stayveer's benefits are greater than its risks and recommended that it can be authorised for use in the EU.
Danish: Det Europæiske Lægemiddelagentur konkluderede, at fordelene ved Stayveer opvejer risiciene, og anbefalede, at det godkendes til anvendelse i EU.
English: Stayveer contains the active substance bosentan.
Danish: Stayveer indeholder det aktive stof bosentan.
English: Why is Stayveer authorised in the EU?
Danish: Hvorfor er Stayveer godkendt i EU?
English: Side effects reported with Stayveer are carefully evaluated and any necessary action taken to protect patients.
Danish: De indberettede bivirkninger ved Stayveer vurderes omhyggeligt, og der tages de nødvendige forholdsregler for at beskytte patienterne.
English: What is Stayveer and what is it used for?
Danish: Hvad er Stayveer, og hvad anvendes det til?
English: In adults, the starting dose is 62.5 mg twice a day for four weeks, which is increased to the usual dose of 125 mg twice a day.
Danish: Voksne bør starte med en dosis på 62,5 mg to gange dagligt i fire uger og derefter øge dosen til den normale dosis på 125 mg to gange dagligt.
English: What are the risks associated with Stayveer?
Danish: Hvilke risici er der forbundet med Stayveer?
English: This is based on two studies in a total of 245 adults with class III or IV disease that was either primary or caused by scleroderma.
Danish: Dette er baseret på to studier hos i alt 245 voksne patienter med klasse III- eller IV-PAH, som enten var primær eller forårsaget af sklerodermi.
English: The active substance in Stayveer, bosentan, blocks a naturally occurring hormone called endothelin-1 (ET-1), which causes blood vessels to narrow.
Danish: Det aktive stof i Stayveer, bosentan, blokerer et naturligt forekommende hormon (såkaldt endothelin-1 (ET-1)), der får blodkarrene til at trække sig sammen.