FrancophonIA/ELRC3.0 huggingface dataset:
English: Equianalgesic potency conversion In patients currently taking opioid analgesics, the starting dose of DUROGESIC should be based on the daily dose of the prior opioid.
Slovenian: Pri bolnikih, ki že prejemajo opioidne analgetike, mora začetni odmerek zdravila DUROGESIC temeljiti na dnevnem odmerku opioida, ki ga je bolnik prejemal pred tem.
English: Concomitant use of mixed opioid agonists/antagonists The concomitant use of buprenorphine, nalbuphine or pentazocine is not recommended.
Slovenian: Sočasna uporaba buprenorfina, nalbufina ali pentazocina ni priporočljiva.
English: • If your patches keep falling off, talk to your doctor, pharmacist or nurse
Slovenian: • Če se vam obliži vedno znova odlepijo, se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
English: However, as the influence of renal impairment on the pharmacokinetics of fentanyl has not been evaluated, caution is advised (see sections 4.2 and 4.4).
Slovenian: Ker pa vpliva okvare ledvic na farmakokinetiko fentanila niso ocenili, je priporočljiva previdnost (glejte poglavje
English: Erectile dysfunction, Sexual dysfunction
Slovenian: Motnje reprodukcije in dojk motnje erekcije, motnje v spolnosti
English: The development of a potentially life-threatening serotonin syndrome may occur with the concomitant use of serotonergic active substances such as Selective Serotonin Re-uptake Inhibitors (SSRIs) and Serotonin Norepinephrine Re-uptake Inhibitors (SNRIs), and with active substances which impair metabolism of serotonin (including Monoamine Oxidase Inhibitors [MAOIs]).
Slovenian: Pri sočasni uporabi serotoninergičnih zdravil, kot so selektivni zaviralci privzema serotonina (SSRISelective Serotonin Re-uptake Inhibitors), zaviralci privzema serotonina-noradrenalina (SNRISerotonin Norepinephrine Re-uptake Inhibitors) in zdravil, ki vplivajo na presnovo serotonina (vključno z zaviralci monoaminooksidaze (MAO)), se lahko pojavi potencialno življenjsko nevaren serotoninski sindrom.
English: Because fentanyl is metabolised to inactive metabolites in the liver, hepatic impairment might delay its elimination.
Slovenian: Fentanil se v jetrih presnovi v v neaktivne presnovke, zato lahko okvara jeter upočasni njegovo odstranjevanje.
English: DUROGESIC provides continuous systemic delivery of fentanyl during the 72-hour application period.
Slovenian: Zdravilo DUROGESIC zagotavlja 72-urno kontinuirano sistemsko preskrbo s fentanilom.
English: Dosage titration should normally be performed in 12 mcg/h or 25 mcg/h increments, although the supplementary analgesic requirements (oral morphine 45/90 mg/day ≈ DUROGESIC 12/25 mcg/h) and pain status of the patient should be taken into account.
Slovenian: Navadno je treba odmerek prilagajati v korakih po 12 mikrogramov/h ali 25 mikrogramov/h, vseeno pa moramo upoštevati dodatne potrebe po analgetikih (peroralni morfin
English: • Some medicines used to treat heartburn or ulcers (such as cimetidine).
Slovenian: • Nekatera zdravila za zdravljenje zgage ali razjed (kot je cimetidin).
English: Respiratory depression
Slovenian: Depresija dihanja
English: Diarrhoea, Dry mouth,
Slovenian: Bolezni prebavil navzea, bruhanje, zaprtje driska, suha usta,
English: (Uncommon, this may affect up to 1 in 100 people)
Slovenian: (občasni, pojavijo se lahko pri največ 1 od 100 bolnikov)
English: Your doctor will decide which strength of DUROGESIC is most suitable for you, taking into account the severity of your pain, your general condition and type of pain treatment that you have received so far.
Slovenian: Zdravnik vam bo na osnovi ocene vaše bolečine, splošnega zdravstvenega stanja in dosedanjega protibolečinskega zdravljenja predpisal za vas najprimernejšo jakost zdravila DUROGESIC.
English: Rare side effects (may affect up to 1 in 1000 people)
Slovenian: Redki (pojavijo se lahko pri največ 1 od 1.000 bolnikov)
English: Do not use DUROGESIC if you are breastfeeding.
Slovenian: Zdravila DUROGESIC ne smete uporabljati med dojenjem.
English: If patients with renal impairment receive DUROGESIC, they should be observed carefully for signs of fentanyl toxicity and the dose reduced if necessary.
Slovenian: Če bolniki z okvaro ledvic prejemajo zdravilo DUROGESIC, jih je treba skrbno opazovati glede znakov toksičnih učinkov fentanila in po potrebi zmanjšati odmerek.
English: Therefore, patients with fever should be monitored for opioid undesirable effects and the DUROGESIC dose should be adjusted if necessary.
Slovenian: Bolnike s zvišano telesno temperaturo je treba skrbno spremljati glede pojava neželenih učinkov opioidov in po potrebi prilagoditi odmerek zdravila DUROGESIC.
English: You should not breastfeed for 3 days after removing your DUROGESIC patch.
Slovenian: Dojiti ne smete še 3 dni po odstranitvi obliža.
English: Concomitant use of mixed opioid agonists/antagonists The concomitant use of buprenorphine, nalbuphine or pentazocine is not recommended (see also section 4.5).
Slovenian: Sočasna uporaba buprenorfina, nalbufina ali pentazocina ni priporočljiva (glejte poglavje 4.5).
English: Table 1: Conversion Table - Multiplication Factors for Converting the Daily Dose of Prior Opioids to the Equianalgesic 24-hour Oral Morphine Dose (mg/day Prior Opioid x Factor = Equianalgesic 24-hour Oral Morphine Dose) Prior Opioid
Slovenian: Preglednica 1: Pretvorbena preglednica - multiplikator pretvorbe dnevnega odmerka predhodnega opioida v 24-urni ekvianalgetični odmerek morfina
English: Used patches should be folded firmly in half so that the sticky side of the patch sticks to itself.
Slovenian: Uporabljene obliže morate prepogniti na pol, z lepljivima stranema skupaj.
English: DUROGESIC can make you drowsy or breathe more slowly.
Slovenian: Zaradi uporabe zdravila DUROGESIC ste lahko omotični ali počasneje dihate.
English: More about using DUROGESIC
Slovenian: Več o uporabi transdermalnih obližev DUROGESIC
English: No risk was identified in the paediatric population beyond that expected with the use of opioids for the relief of pain associated with serious illness and there does not appear to be any paediatric-specific risk associated with DUROGESIC use in children as young as 2 years old when used as directed.
Slovenian: Razen pričakovanega tveganja ob uporabi opioidov za lajšanje bolečin, povezanih z resno boleznijo, v pediatrični populaciji niso opazili nobenega drugega tveganja.
English: • Never divide or cut the patch
Slovenian: • Obliža ne smete razrezati ali razpoloviti.
English: UNIQUE IDENTIFIER - 2D BARCODE <Not applicable>
Slovenian: EDINSTVENA OZNAKA - DVODIMENZIONALNA ČRTNA KODA
English: Examples of active substance that may decrease fentanyl plasma concentrations include: carbamazepine, phenobarbital, phenytoin and rifampicin (this list is not exhaustive).
Slovenian: karbamazepin, fenobarbital, fenitoin in rimfapicin (ta seznam ni popoln).
English: The adverse reactions reported with the use of DUROGESIC from these clinical studies, including the above-mentioned adverse reactions, and from post-marketing experiences are listed below in Table 5.
Slovenian: V preglednici 5 so, vključno z zgornjimi, navedeni neželeni učinki, o katerih so poročali v kliničnih študijah in v obdobju trženja zdravila DUROGESIC.
English: More than one DUROGESIC patch may be used for doses greater than 100 mcg/h.
Slovenian: Pri odmerkih večjih od 100 mikrogramov/h lahko uporabljamo več obližev hkrati.
English: • If you have any further questions, ask your doctor, pharmacist or nurse
Slovenian: - Če imate dodatna vprašanja, se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
English: What DUROGESIC looks like and contents of the pack [To be completed nationally]
Slovenian: Zdravilo DUROGESIC vsebuje {ime pomožne(ih) snovi} [To be completed nationally]
English: Elderly patients should be observed carefully for signs of fentanyl toxicity and the dose reduced if necessary (see section 4.4).
Slovenian: Starejše bolnike je treba skrbno opazovati glede znakov toksičnosti fentanila in po potrebi zmanjšati odmerek (glejte poglavje 4.4).
English: If a patch falls off
Slovenian: Če se vam obliž odlepi
English: Several days should elapse before a new patch is applied to the same area of the skin.
Slovenian: Šele po nekaj dneh lahko zopet damo obliž na isto mesto.
English: When you are wearing the patch do not expose it to direct heat such as heating pads, electric blankets, hot-water bottles, heated water beds or heat or tanning lamps.
Slovenian: Med uporabo, obliža ne izpostavljajte neposrednemu viru toplote, kot so grelne blazine, električne odeje, termoforji, ogrevane vodne postelje, toplotne luči ali luči za umetno porjavitev.
English: DUROGESIC should be administered only to opioid-tolerant children age 2 years or older (see section 4.2).
Slovenian: Zdravilo DUROGESIC lahko prejemajo samo otroci, stari 2 leti ali več, pri katerih se je že razvila toleranca na opioide (glejte poglavje 4.2).
English: To derive the DUROGESIC dosage corresponding to the calculated 24-hour, equianalgesic morphine dosage, use dosage-conversion Table 2 or 3 as follows: a. Table 2 is for adult patients who have a need for opioid rotation or who are less clinically stable (conversion ratio of oral morphine to transdermal fentanyl approximately equal to b. Table 3 is for adult patients who are on a stable, and well-tolerated, opioid regimen (conversion ratio of oral morphine to transdermal fentanyl approximately equal to 100:1).
Slovenian: Za pretvorbo 24-urnega ekvianalgetičnega odmerka morfina v ustrezni odmerek zdravila Durogesic uporabite preglednico 2 ali 3 kot sledi: a. Preglednica 2 je namenjena odraslim bolnikom, pri katerih je potrebno menjavanje opioidov ali za klinično manj stabilne bolnike (razmerje za pretvorbo peroralnega morfina v transdermalni fentanil je približno 150:1).
English: CYP3A4 Inducers
Slovenian: Induktorji CYP3A4
English: It belongs to a group of strong painkillers called opioids.
Slovenian: Fentanil uvrščamo v skupino močnih protibolečinskih učinkovin, ki jih imenujemo opioidi.
English: hydroxyzine, or lorazepam) and medicines for mental conditions (anti-psychotics, such as aripiprazole, haloperidol, olanzapine, risperidone, or phenothiazines).
Slovenian: • Zdravila, ki seuporabljajo za pomiritev (pomirjevala, kot so alprazolam, klonazepam, diazepam, hidroksizin ali lorazepam) in zdravila za zdravljenje duševnih motenj (antipsihotiki, kot so aripiprazol, haloperidol, olanzapin, risperidon ali fenotiazin).
English: • Some medicines used to treat depression or Parkinson's disease called MAOIs (such as isocarboxazid, phenelzine, selegiline, or tranylcypromine).You should not take DUROGESIC
Slovenian: • Nekatera zdravila, ke se uporabljajo za zdravljenje depresije ali Parkinsonove bolezni, imenovana zaviralci MAO (kot so izokarboksazid, fenelzin, selegilin ali tranilcipromin).
English: What you need to know before you use DUROGESIC
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo DUROGESIC Ne uporabljajte zdravila DUROGESIC
English: If you, or your partner or carer, notice that the person wearing the patch is unusually drowsy, with slow or shallow breathing: - Take the patch off - Call a doctor, or go to your nearest hospital straight away - Keep the person moving and talking as much as possible
Slovenian: Če vi, vaš partner ali negovalec opazite, da je oseba, ki nosi obliž neobičajno zaspana ter počasneje ali bolj plitvo diha:
English: Anaphylactic reaction, Anaphylactoid reaction
Slovenian: anafilaktična reakcija, anafilaktoidn a reakcija
English: Contents of the pack and other information What DUROGESIC contains [To be completed nationally]
Slovenian: Vsebina pakiranja in dodatne informacije Kaj vsebuje zdravilo DUROGESIC
English: Tolerance, physical dependence, and psychological dependence can develop on repeated use of DUROGESIC (see section 4.4).
Slovenian: Pri dolgotrajni uporabi zdravila DURIGESIC se lahko pojavijo toleranca, fizična in psihična odvisnost (glejte poglavje 4.4).
English: • Constricted pupils (miosis)
Slovenian: • zožanje zenic (mioza)
English: Therefore, the product information of the CYP3A4 inhibitor must be consulted for the active substance's half-life and duration of the inhibitory effect before applying the first DUROGESIC patch.
Slovenian: Zato je treba pred prvo namestitvijo transdermalnega obliža DUROGESIC prebrati informacije o zdravilu zaviralca CYP3A4 glede razpolovnega časa ter čas trajanja zaviranja.
English: • Headache
Slovenian: • driska
English: Abdominal pain, Abdominal pain upper, Dyspepsia
Slovenian: bolečine v trebuhu, bolečine v zgornjem delu trebuha, dispepsija ileus subileus
English: Therefore, the use of any of these medicinal products concomitantly with DUROGESIC requires special patient care and observation.
Slovenian: Zato sočasna uporaba zgoraj navedenih zdravil zahteva skrbno nego in opazovanje bolnika.
English: Examples of active substances that may increase fentanyl concentrations include: amiodarone, cimetidine, clarithromycin, diltiazem, erythromycin, fluconazole, itraconazole, ketoconazole, nefazodone, ritonavir, verapamil and voriconazole (this list is not exhaustive).
Slovenian: cimetidin, klaritromicin, diltiazem, eritromicin, flukonazol, itrakonazol, ketokonazol, nefazodon,
English: Apply your patch on
Slovenian: Obliž si nalepite v
English: Palpitations, Tachycardia
Slovenian: Srčne bolezni palpitacije, tahikardija bradikardija, cianoza
English: To convert opioid-tolerant patients from oral or parenteral opioids to DUROGESIC refer to Equianalgesic potency conversion below.
Slovenian: Bolniki, pri katerih se je že razvila toleranca na opioide PRI ZAMENJAVI PERORALNEGA ALI PARENTERALNEGA ZDRAVLJENJA Z OPIOIDI Z ZDRAVILOM DUROGESIC GLEJTE SPODNJI ODSTAVEK PRETVORBA V
English: Accidental transfer of a fentanyl patch to the skin of a non-patch wearer (particularly a child), while sharing a bed or being in close physical contact with a patch wearer, may result in an opioid overdose for the non-patch wearer.
Slovenian: med souporabo postelje ali pri tesnem fizičnem stiku z osebo, ki nosi obliž, lahko pri osebi, ki obliža ne uporablja, vodi v prevelik odmerek opioida.
English: • Nausea, vomiting, constipation
Slovenian: • slabost (navzea), bruhanje, zaprtje
English: Underlying, symptomatic hypotension and/or hypovolaemia should be corrected before treatment with fentanyl transdermal patches is initiated.
Slovenian: Pomembno je, da se pred začetkom zdravljenja s fentanilom v obliki transdermalnih obližev simptomatska hipotenzija in/ali hipovolemija popravita.
English: Patients should be advised that if accidental patch transfer occurs, the transferred patch must be removed immediately from the skin of the non-patch wearer (see section
Slovenian: Bolnikom svetujte, naj v primeru nenamernega prenosa obliž takoj odstranijo s kože osebe, ki zdravila ne uporablja (glejte poglavje 4.9).
English: Cases of serotonin syndrome have been reported when fentanyl was administered concomitantly with highly serotonergic drugs (see sections 4.4. and 4.5).
Slovenian: Pri sočasni uporabi fentanila in močno serotoninergičnih zdravil (glejte poglavji 4.4 in 4.5) so poročali o primerih serotoninskega sindroma.
English: Chronic pulmonary disease
Slovenian: Bolezni sečil zastoj urina
English: 30b pethidine oral parenteral
Slovenian: 30b petidin peroralna parenteralna
English: Calculate the 24-hour dose (mg/day) of the opioid currently being used.
Slovenian: Izračunajte količino analgetika (opioid, ki ga bolnik trenutno jemlje), ki je bila potrebna v zadnjih 24-ih urah (mg/kg).
English: If elderly patients receive DUROGESIC, they should be observed carefully for signs of fentanyl toxicity and the dose reduced if necessary (see section 5.2).
Slovenian: Če starejši bolniki prejemajo zdravilo DUROGESIC, jih je treba skrbno opazovati glede znakov zastrupitve s fentanilom in po potrebi zmanjšati odmerek (glejte poglavje 5.2).
English: Use of DUROGESIC in the opioid-naïve patient has been associated with very rare cases of significant respiratory depression and/or fatality when used as initial opioid therapy, especially in patients with non-cancer pain.
Slovenian: Bolniki, ki še niso jemali opioidov ali jih ne prenašajo Uporaba zdravila DUROGESIC pri bolnikih, ki še niso jemali opioidov, je povezana z zelo redkimi primeri resne depresije dihanja in/ali smrti, kadar se je uporabljal kot začetno opioidno zdravljenje,
English: Co-administration of fentanyl with a serotonergic medicinal products, such as a Selective Serotonin Re-uptake Inhibitor (SSRI) or a Serotonin Norepinephrine Re-uptake Inhibitor (SNRI) or a Monoamine Oxidase Inhibitor (MAOI), may increase the risk of serotonin syndrome, a potentially life threatening condition.
Slovenian: Sočasna uporaba fentanila in serotoninergičnih zdravil kot so SSRI, SNRI ali zaviralci MAO lahko poveča tveganje za pojav potencialno življensko nevarnega serotoninskega sindroma.
English: • DUROGESIC is a medicine that could be life-threatening to children, even if the patches have been used.
Slovenian: • Zdravilo DUROGESIC je lahko za otroke smrtno nevarno.
English: Talk to your doctor or pharmacist before using this medicine if any of the following apply to youyour doctor may need to check you more closely if:
Slovenian: Bodite posebno pozorni pri uporabi zdravila DUROGESIC Če karkoli od spodaj navedenega velja za vas, to povejte svojemu zdravniku ali farmacevtu pred uporabo tega zdravila, ker vas bo morda moral natančneje pregledati: • če ste kadar koli imeli težave s pljuči ali dihanjem
English: • Some medicines used to treat depression called SSRIs or SNRIs (such as citalopram, duloxetine,
Slovenian: • Nekatera zdravila, ki se uporabljajo za zdravljenje depresije, imenovana SSRI (zaviralci ponovnega privzema serotonina) ali SNRI (zavirlci ponovnega privzema serotoninanoradrenalina) (kot so citalopram, duloksetin, escitalopram, fluoksetin, fluvoksamin, paroksetin,
English: • Stomach pain or indigestion
Slovenian: • bolečine v trebuhu ali prebavne motnje
English: Patients can then switch to DUROGESIC.
Slovenian: Nato lahko te opioide zamenjamo z zdravilom DUROGESIC.
English: • As soon as you take a patch off, fold it firmly in half so that the sticky side sticks to itself
Slovenian: 4. korak: Obliž zavrzite • Takoj, ko obliž odstranite, ga prepognite na pol, z lepljivo stranjo obrnjeno navznoter.
English: • You have breathing difficulties, with slow or shallow breathing Do not use this medicine if any of the above apply to you or your child.
Slovenian: Ne uporabljajte tega zdravila, če karkoli od navedenega velja za vas ali vašega otroka.
English: UNIQUE IDENTIFIER - HUMAN READABLE DATA <Not applicable>
Slovenian: EDINSTVENA OZNAKA - V BERLJIVI OBLIKI Navedba smiselno ni potrebna.
English: Posology
Slovenian: Prebavila
English: Operations
Slovenian: Operativni posegi
English: There have been reports also of newborn infants experiencing withdrawal effects after their mothers have used DUROGESIC for a long time during pregnancy.
Slovenian: Pri novorojencih žensk, ki so se med nosečnostjo dolgo časa zdravile z zdravilom DUROGESIC, so poročali o odtegnitvenih učinkih.
English: This is because fentanyl concentrations fall gradually after DUROGESIC is removed.
Slovenian: Serumske koncentracije fentanila po odstranitvi zdravila DUROGESIC padajo postopno.
English: Opioid withdrawal symptoms (such as nausea, vomiting, diarrhoea, anxiety, and shivering) are possible in some patients after conversion from their previous opioid analgesic to DUROGESIC or if therapy is stopped suddenly (see section 4.2).
Slovenian: Simptomi odtegnitve opioidov (kot so navzea, bruhanje, driska, anksioznost, drgetanje) se lahko pojavijo pri posameznih bolnikih, ki preidejo s prejšnjega opioidnega analgetika na zdravilo
English: DUROGESIC should be applied immediately upon removal from the sealed package.
Slovenian: Zdravilo DUROGESIC je treba nalepiti na kožo takoj, ko ga vzamemo iz zavarjene vrečice.
English: Patients with hepatic impairment should be observed carefully for signs of fentanyl toxicity and the dose of DUROGESIC should be reduced if necessary (see section 4.4).
Slovenian: Bolnike z okvaro ledvic je treba skrbno spremljati glede znakov toksičnosti fentanila in, če je potrebno, zmanjšati odmerek zdravila DUROGESIC (glejte poglavje 4.4).
English: The polymer matrix and the diffusion of fentanyl through the layers of the skin ensure that the release rate is relatively constant.The concentration gradient existing between the system and the lower concentration in the skin drives drug release.
Slovenian: Koncentracijski gradient med sistemom obliža in manjšo koncentracijo v koži povzroči sproščanje učinkovine.
English: • Some medicines used to treat nausea or motion sickness (such as phenothiazines).
Slovenian: • Nekatera zdravila za zdravljenje slabosti (navzee) ali slabosti zaradi vožnje (kot so fenotiazini).
English: The release liner for the patch is slit.
Slovenian: Zaščitna plast na obližu je prerezana.
English: Some patients may require additional or alternative methods of opioid administration when the DUROGESIC dose exceeds 300 mcg/h.
Slovenian: Če odmerek zdravila DUROGESIC preseže 300 mikrogramov/h, bodo nekateri bolniki morda potrebovali dodatne ali druge metode analgezije.
English: Opioid-naïve patients
Slovenian: Predhodni opioid
English: There are no adequate data from the use of DUROGESIC in pregnant women.
Slovenian: O uporabi fentanila med nosečnostjo ni dovolj podatkov.
English: Neonatal withdrawal syndrome has been reported in newborn infants with chronic maternal use of DUROGESIC during pregnancy.
Slovenian: Pri novorojencih žensk, ki so se med nosečnostjo dolgotrajno zdravile z zdravilom DUROGESIC, so poročali o odtegnitvenem sindromu.
English: • Spinning sensation (vertigo)
Slovenian: • občutek vrtenja (vrtoglavica)
English: The potential for serious or life-threatening hypoventilation exists even if the lowest dose of DUROGESIC is used in initiating therapy in opioid-naïve patients (see sections 4.4 and
Slovenian: Kljub uvedbi najmanjšega odmerka zdravila DUROGESIC pri teh bolnikih še vedno obstaja možnost pojava resne ali življenjsko nevarne hipoventilacije (glejte poglavji 4.4 in 4.9).
English: Some studies in rats have revealed reduced fertility and enhanced embryo mortality at maternally toxic doses (see section 5.3).
Slovenian: Kliničnih podatkov o vplivu fentanila na plodnost ni. Nekaj študij pri podganah je pokazalo zmanjšano plodnost in povečano umrljivot zarodkov pri odmerkih, toksičnih za mater (glejte poglavje
English: Table 3: Recommended starting dosage of DUROGESIC based upon daily oral morphine dosage (for patients on stable and well tolerated opioid therapy: conversion ratio of oral morphine to transdermal fentanyl is approximately equal to 100:1)
Slovenian: Preglednica 3: Priporočeni začetni odmerek zdravila DUROGESIC, glede na dnevni peroralni odmerek morfina (za bolnike, ki prejemajo stalen odmerek opioida in ga dobro prenašajo: pretvorbeno razmerje peroralnega morfina v transdermalni fentanil je približno 100:1) Peroralni 24-urni odmerek morfina (mg/dan)
English: Do not use DUROGESIC after the expiry date which is stated on the carton and sachet.
Slovenian: Kako dolgo je treba hraniti zdravilo DUROGESIC Zdravila Durogesic ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na blazinici poleg oznake “Uporabno do:”.
English: DUROGESIC is not recommended for use in patients who require the concomitant administration of an MAOI.
Slovenian: Uporaba zdravila DUROGESIC pri bolnikih, ki sočasno jemljejo zaviralce MAO, ni priporočljiva.
English: - Don't put a tight or elasticated band over the patch
Slovenian: - ne uporabljajte vročih termalnih in masažnih bazenov, - obliža ne prekrijte s tesnimi ali elastičnimi trakovi.
English: • Muscle twitching
Slovenian: • trzanje mišic
English: • While you are wearing the patch do not expose it to direct heat such as heating pads, electric blankets, hot-water bottles, heated water beds, heat or tanning lamps.
Slovenian: • Obliža ne izpostavljajte neposrednim virom toplote, kot so grelne blazine, električne odeje, termoforji, ogrevane vodne postelje, toplotne luči in luči za umetno porjavitev, sončenje, podaljšane vodne kopeli ali savne.
English: Discontinuation of DUROGESIC
Slovenian: Shranjevanje zdravila DUROGESIC
English: Cardiac disease
Slovenian: Ušesne bolezni,