FrancophonIA/ELRC3.0 huggingface dataset:
English: Use dosing intervals of 3 - 4 hours (this corresponds to a maximum of 6 administrations per day).
Slovenian: Interval med posameznimi odmerki naj bo 3 - 4 ure (to ustreza največ 6 aplikacijam na dan).
English: A mass-balance study was done using 3H-iloprost in healthy subjects.
Slovenian: Študija masnega ravnovesja je bila opravljena pri zdravih osebah s pomočjo 3H-iloprosta.
English: Ventavis should only be used during pregnancy if your doctor decides that the potential benefit outweighs the potential risk to you and the foetus.
Slovenian: Zdravilo Ventavis se sme uporabljati med nosečnostjo le, če zdravnik presodi, da so možne koristi večje od možnega tveganja za vas in plod.
English: Patients with a creatinine clearance of ≤30 ml/min were not investigated in the clinical trials.
Slovenian: Bolniki z očistkom kreatinina ≤ 30 ml/min niso bili vključeni v klinična preskušanja.
English: Animal studies have not shown harmful effect of iloprost on fertility.
Slovenian: Študije na živalih ne kažejo škodljivih učinkov iloprosta na plodnost.
English: Patients with concomitant acute pulmonary infections, COPD and severe asthma should be carefully monitored.
Slovenian: Bolnike s sočasnimi akutnimi pljučnimi okužbami, KOPB in hudo astmo je treba skrbno spremljati.
English: Stop using Ventavis and tell your doctor immediately.
Slovenian: Prenehajte uporabljati zdravilo Ventavis in takoj obvestite zdravnika.
English: Other medicines and Ventavis
Slovenian: Druga zdravila in zdravilo Ventavis
English: In comparable embryotoxicity studies in rabbits and monkeys no such digit anomalies or other gross-structural anomalies were observed even after considerably higher dose levels which exceeded the human dose multiple times.
Slovenian: V primerljivih študijah embriotoksičnosti pri kuncih in opicah takih anomalij prstov ali drugih večjih strukturnih anomalij niso opazili, niti pri znatno večjih odmerkih, ki so večkrat presegli odmerke pri človeku.
English: Symptoms of overdoses are mainly related to the vasodilatory effect of iloprost.
Slovenian: Simptomi prevelikega odmerjanja so v glavnem povezani z vazodilatornim učinkom iloprosta.
English: • if you have had a stroke within the last 3 months, or any other occurrence that reduced the blood supply to the brain (e.g. transient ischaemic attack),
Slovenian: • če ste v zadnjih 3 mesecih imeli možgansko kap ali kakšno drugo stanje, ki zmanjša preskrbo možganov s krvjo (npr. tranzitorna ishemična ataka),
English: Treatment of adult patients with primary pulmonary hypertension, classified as NYHA functional class III, to improve exercise capacity and symptoms.
Slovenian: Zdravljenje odraslih bolnikov s primarno pljučno hipertenzijo, opredeljeno kot III. funkcijski razred po klasifikaciji NYHA, za izboljšanje telesne zmogljivosti in lajšanje simptomov.
English: Women with pulmonary hypertension (PH) should avoid pregnancy as it may lead to life-threatening exacerbation of the disease.
Slovenian: Ženske s pljučno hipertenzijo (PH - pulmonary hypertension) bi se morale izogibati nosečnosti, ker lahko pride do življenjsko ogrožajočega poslabšanja bolezni.
English: The mean daily inhaled dose was 27 microgram and the mean number of inhalations per day was 5.6.
Slovenian: Povprečni dnevni inhalirani odmerek je bil 27 mikrogramov, povprečno število inhalacij na dan pa 5,6.
English: Total plasma protein binding of iloprost is concentration-independent in the range of 30 to 3,000 picogram/ml and amounts to approximately 60%, of which 75% is due to albumin binding.
Slovenian: Celokupna vezava iloprosta na beljakovine v plazmi je neodvisna od koncentracije v mejah od 30 do 3.000 pikogramov/ml in znaša približno 60 %; od tega 75 % predstavlja vezavo na albumin.
English: There is a limited amount of data from the use of iloprost in pregnant women.
Slovenian: Podatkov o uporabi iloprosta pri nosečnicah je malo.
English: He/she may consider adjusting your dose or changing your treatment.
Slovenian: Morda se bo odločil za prilagoditev odmerka ali spremembo zdravljenja.
English: • If you are pregnant, think you might be or are planning to have a baby, tell your doctor straight away.
Slovenian: • Če ste noseči ali dojite, menite, da ste noseči ali načrtujete zanositev, o tem takoj obvestite zdravnika.
English: Most people will have 6 to 9 inhalation sessions spread throughout the day.
Slovenian: Pri večini ljudi zadostuje 6 do 9 inhalacij na dan, razporejenih preko celega dneva.
English: The rate of responders to iloprost was 16.8% (17/101) and the rate of responders in the placebo group was 4.9% (5/102) (p=0.007).
Slovenian: Delež tistih, ki so se odzvali na iloprost, je bil 16,8 % (17/101), delež odzivov v placebo skupini pa 4,9 % (5/102) (p = 0,007).
English: If a pregnancy occurs, taking into account the potential maternal benefit, the use of Ventavis during pregnancy may be considered, only following careful benefit-risk evaluation, in those women who choose to continue their pregnancy, despite the known risks of pulmonary hypertension during pregnancy.
Slovenian: Če ženska zanosi, je treba upoštevati možne koristi za mater, ker se zdravilo Ventavis lahko uporablja med nosečnostjo le po skrbni oceni koristi in tveganj pri tistih ženskah, ki se odločijo za nadaljevanje nosečnosti kljub znanim tveganjem za pljučno hipertenzijo med nosečnostjo.
English: • If you could get pregnant, use reliable contraception from the time you start treatment and during treatment.
Slovenian: • Če je možno, da bi lahko zanosili, potem od takrat ko začnete zdravljenje in med zdravljenjem uporabljajte učinkovito kontracepcijsko metodo.
English: In the iloprost group the NYHA class was improved in 26% of patients (placebo: 15%) (p = 0.032), unchanged in 67.7% of patients (placebo: 76%) and deteriorated in 6.3% of patients (placebo: 9%).
Slovenian: V skupini z iloprostom se je razred po klasifikaciji NYHA izboljšal pri 26 % bolnikov (placebo 15 %) (p = 0,032), ostal nespremenjen pri 67,7 % bolnikov (placebo 76 %) in se poslabšal pri 6,3 % bolnikov
English: Considering the high pharmacological potency of iloprost and the absolute doses required for therapeutic purposes the results obtained in acute toxicity studies do not indicate a risk of acute adverse effects in humans.
Slovenian: Ob upoštevanju visoke farmakološke učinkovitosti iloprosta ter absolutnih odmerkov, ki so potrebni za doseganje učinkov zdravljenja, izsledki študij akutne toksičnosti ne kažejo, da bi pri človeku obstajalo tveganje za pojav akutnih neželenih učinkov.
English: Animal studies have shown reproductive effects (see section 5.3).
Slovenian: Študije na živalih so pokazale vpliv na sposobnost razmnoževanja (glejte poglavje 5.3).
English: Your doctor will adjust Venta-Neb to the programme you need to receive the dose prescribed for you.
Slovenian: Zdravnik vam bo nastavil Venta-Neb na program, s katerim boste lahko prejeli predpisani odmerek.
English: Tell your doctor if you have a lung infection, severe asthma, or chronic lung disease (chronic obstructive pulmonary disease).
Slovenian: Zdravnika obvestite, če imate okužbo pljuč, hudo astmo ali kronično pljučno obolenje (kronično obstruktivno pljučno bolezen).
English: Suitable inhalation device (nebuliser) to be used
Slovenian: Ustrezen pripomoček za inhaliranje (nebulator), ki ga je treba uporabiti
English: Results of in vitro studies reveal that CYP 450-dependent metabolism plays only a minor role in the biotransformation of iloprost.
Slovenian: Izsledki in vitro študij kažejo, da ima od CYP 450 odvisna presnova le manjšo vlogo v biotransformaciji iloprosta.
English: Gender Gender is not of clinical relevance to the pharmacokinetics of iloprost.
Slovenian: Spol ne vpliva klinično pomembno na farmakokinetiko iloprosta.
English: • If you suffer from a weak heart condition such as right heart failure, and feel that your disease is worsening, tell your doctor.
Slovenian: • Če imate oslabljeno srce, npr. desnostransko srčno popuščanje in imate občutek, da se je bolezen poslabšala, obvestite zdravnika.
English: • Do NOT let Ventavis solution come into contact with your skin or eyes.
Slovenian: • Pazite, da zdravilo Ventavis NE pride v stik s kožo ali očmi.
English: Depending on your individual needs, Ventavis can be used for long term treatment.
Slovenian: Glede na vaše potrebe se zdravilo Ventavis lahko uporablja za dolgotrajno zdravljenje.
English: The most frequently observed adverse reactions (≥ 20 %) in clinical trials include vasodilatation (including hypotension), headache and cough.
Slovenian: Najpogostejši neželeni učinki (≥ 20 %), ki so jih opazili v kliničnih preskušanjih, so vazodilatacija (vključno s hipotenzijo), glavobol in kašelj.
English: • Dilatation of arterioles and venules
Slovenian: • razširitev arteriol in venul,
English: This medicinal product contains small amounts of ethanol (alcohol), less than 100 mg per dose.
Slovenian: To zdravilo vsebuje majhne količine etanola (alkohola), in sicer manj kot 100 mg na odmerek.
English: First dosing with 2.5 microgram should be done even if patients had already been stable on 5 microgram inhaled with an alternative device (see section 4.2).
Slovenian: Prvo odmerjanje z 2,5 mikrograma je treba narediti tudi, če so bili bolniki stabilni že pri odmerku 5 mikrogramov, inhaliranim z drugim pripomočkom (glejte poglavje 4.2).
English: Estimated inhalation time
Slovenian: Predviden inhalacijski čas
English: Ventavis contains ethanol
Slovenian: Zdravilo Ventavis vsebuje etanol
English: Symptoms can be flushing or reddening of the face.
Slovenian: Simptoma sta lahko pordelost ali pordevanje obraza.
English: Pulmonary vasodilators may significantly worsen the cardiovascular status of patients with pulmonary veno-occlusive disease.
Slovenian: Pljučni vazodilatatorji lahko močno poslabšajo kardiovaskularno stanje bolnikov s pljučno venookluzivno boleznijo.
English: • Follow carefully any instructions that come with the nebuliser.
Slovenian: • Skrbno upoštevajte navodila, ki so priložena nebulatorju.
English: • if you are at risk of bleeding- for example, if you have an active ulcer of the stomach or of the first part of the small intestine (duodenal ulcers), if you have suffered a physical injury (trauma), if you are at risk of bleeding within the skull,
Slovenian: • če pri vas obstaja tveganje za krvavitve - npr. če imate aktivno razjedo želodca ali začetnega dela tankega črevesa (duodenalni ulkus), če ste imeli telesno poškodbo (travmo) ali če pri vas obstaja tveganje za krvavitve znotraj lobanje,
English: Ask your doctor to have someone help you become thoroughly familiar with the use of the nebuliser.
Slovenian: Prosite zdravnika, da vam nekdo pomaga, dokler niste dovolj izkušeni z uporabo nebulatorja.
English: Do not change the recommended dose without consulting your doctor first.
Slovenian: Priporočenega odmerka ne spreminjajte brez predhodnega posveta z zdravnikom.
English: The pulmonary vasodilatory effect of each single inhalation levels off within one to two hours.
Slovenian: V pljučih vazodilatorni učinek vsake posamezne inhalacije izzveni v eni do dveh urah.
English: These alterations are not considered as teratogenic effects, but are most likely related to iloprost induced growth retardation in late organogenesis due to haemodynamic alterations in the foetoplacental unit.
Slovenian: Menijo, da pri teh spremembah ne gre za teratogene učinke, temveč so najverjetneje posledica z iloprostom povzročenega zastoja v rasti v obdobju pozne organogeneze zaradi hemodinamskih sprememb v placenti.
English: Very low levels of iloprost into milk were observed in rats (see section 5.3).
Slovenian: Pri podganah so opazili zelo nizke vrednosti iloprosta v mleku (glejte poglavje 5.3).
English: Ventavis is used to treat moderate cases of primary pulmonary hypertension (PPH) in adult patients.
Slovenian: Zdravilo Ventavis se uporablja za zdravljenje zmerne primarne pljučne hipertenzije (PPH) pri odraslih bolnikih.
English: • If you suffer from pulmonary hypertension, avoid getting pregnant as pregnancy may lead to a worsening of your condition and may even endanger your life.
Slovenian: • Če imate pljučno hipertenzijo, se izogibajte zanositvi, saj lahko nosečnost poslabša vašo bolezen ali celo ogrozi vaše življenje.
English: • If you experience difficulty breathing, cough up blood, and/or sweat excessively these may be signs that you have water in the lungs (lung oedema).
Slovenian: • Če imate težave pri dihanju, izkašljujete kri in/ali se zelo potite, so to lahko znaki tekočine v pljučih (pljučnega edema).
English: The occurrence of peripheral oedema can be related to the deterioration of the disease or insufficient effectiveness of the product.
Slovenian: Pojavljanje perifernega edema je lahko povezano z napredovanjem bolezni ali nezadostno učinkovitostjo zdravila.
English: If you have kidney or liver problems
Slovenian: Če imate okvaro ledvic ali jeter
English: Should signs of pulmonary oedema occur, the possibility of associated pulmonary veno-occlusive disease should be considered and treatment with Ventavis should be discontinued.
Slovenian: Če se pojavijo znaki pljučnega edema, je treba pomisliti na možnost pridružene pljučne venookluzivne bolezni in zdravljenje z zdravilom Ventavis prekiniti.
English: In subjects with normal renal and hepatic function, the disposition of iloprost following intravenous infusion is characterised in most cases by a two-phase profile with mean half-lives of 3 to 5 minutes and 15 to 30 minutes.
Slovenian: Pri osebah z normalnim ledvičnim in jetrnim delovanjem je po intravenskem infundiranju za porazdelitev iloprosta v večini primerov značilen dvofazni profil s povprečnimi razpolovnimi časi od 3 do 5 minut in od 15 do 30 minut.
English: − Cerebrovascular events (e.g. transient ischaemic attack, stroke) within the last 3 months.
Slovenian: - cerebrovaskularni dogodki (npr. prehodna možganska ishemija, kap) v zadnjih 3 mesecih
English: They should both have the same colour, either red for the 2.5 microgram dose or purple for the 5 microgram dose.
Slovenian: Oba morata biti iste barve, rdeča za 2,5-mikrogramski odmerek in vijolična za 5-mikrogramski odmerek.
English: Prolonged oral treatment with iloprost clathrate in dogs up to one year was associated with slightly increased fasted serum glucose levels.
Slovenian: Dolgotrajno (do enega leta trajajoče) peroralno zdravljenje z iloprost klatratom pri psih je bilo povezano z nekoliko povečanimi vrednostmi glukoze v serumu na tešče.
English: Symptoms can include swelling of feet and ankles, shortness of breath, palpitations, urinating more frequently at night or oedema.
Slovenian: Simptomi lahko vključujejo otekanje nog in gležnjev, kratko sapo, palpitacije, pogosto uriniranje ponoči ali otekanje.
English: • The nebuliser turns Ventavis solution into a mist which you breathe in through your mouth.
Slovenian: • Nebulator spremeni raztopino zdravila Ventavis v meglico, ki jo vdihnete skozi usta.
English: Women of childbearing potential should use effective contraceptive measures during treatment with Ventavis.
Slovenian: Ženske v rodni dobi morajo med zdravljenjem z zdravilom Ventavis uporabljati učinkovito kontracepcijsko metodo.
English: Two programmes can be operated: 3.
Slovenian: Na voljo sta dva programa.
English: • Increase of capillary density and reduction of increased vascular permeability caused by mediators such as serotonin or histamine in the microcirculation
Slovenian: • povečanje gostote kapilar in zmanjšanje povečane žilne permeabilnosti, ki jo povzročajo mediatorji kot so serotonin ali histamin v mikrocirkulaciji, • stimulacija endogene fibrinolize.
English: − Severe coronary heart disease or unstable angina.
Slovenian: - huda koronarna srčna bolezen ali nestabilna angina pektoris
English: The duration of an inhalation session with Breelib nebuliser is approximately 3 minutes, which reflects the higher delivery rate of the Breelib compared to other nebulisers.
Slovenian: Inhalacija z nebulatorjem Breelib traja približno 3 minute, kar kaže na večjo hitrost dovajanja zdravila z nebulatorjem Breelib v primerjavi z drugimi nebulatorji.
English: The pulmonary vasodilatory effect of inhaled iloprost is of short duration (one to two hours).
Slovenian: Vazodilatatorni učinek inhaliranega iloprosta v pljučih je kratkotrajen (ena do dve uri).
English: • awareness of fast or hard heartbeat (palpitations)
Slovenian: • občutek hitrega in močnega bitja srca (palpitacije)
English: Systemic exposures exceeded human therapeutic exposures after inhalation by factors of more than 10 (Cmax, cumulative AUC).
Slovenian: Po inhalaciji je sistemska izpostavljenost za več kot 10-krat presegla terapevtsko izpostavljenost po inhalaciji pri človeku (Cmax, kumulativni AUC).
English: In case of deterioration or worsening of right heart failure transfer to other medicinal products should be considered.
Slovenian: V primeru napredovanja ali poslabšanja desnostranskega srčnega popuščanja je treba razmisliti o možnosti uporabe kakšnega drugega zdravila.
English: If any of these happen when you have used more Ventavis than you should:
Slovenian: Če se pojavi kateri koli od teh simptomov, potem ko ste uporabili večji odmerek zdravila Ventavis, kot bi smeli:
English: During nebulisation sessions a facial mask must be avoided and only a mouthpiece should be used.
Slovenian: Med inhalacijo z nebulatorjem se je treba izogibati uporabi maske za obraz in uporabljati le ustnik.
English: Before taking any medicine ask your doctor or pharmacist, who has more information on medicines to be careful with or avoid when using Ventavis.
Slovenian: Preden začnete jemati katero koli zdravilo, se posvetujte z zdravnikom ali farmacevtom, ki imata več podatkov o tem, katerim zdravilom se je treba izogibati ali morate biti pri njihovem jemanju previdni,
English: If you forget to use Ventavis
Slovenian: Če ste pozabili uporabiti zdravilo Ventavis
English: Undesirable exposure to Ventavis
Slovenian: Neželena izpostavljenost zdravilu Ventavis
English: • If you have liver problems or very severe kidney problems, requiring dialysis, tell your doctor.
Slovenian: • Če imate težave z jetri ali hude ledvične težave, pri katerih je potrebna dializa, se posvetujte z zdravnikom.
English: Care should be exercised during initiation of therapy until any effects on the individual have been determined.
Slovenian: Pri uvedbi zdravljenja je potrebna previdnost, dokler ni ugotovljeno, kako le-to učinkuje na posameznika.
English: The following pharmacological effects have been observed in vitro:
Slovenian: V študijah in vitro so opazili naslednje farmakološke učinke:
English: A cautious initial dose titration using dosing intervals of 3-4 hours is recommended (see section 4.2).
Slovenian: Priporočljivo je, da se začetni odmerek titrira previdno, interval med posameznimi odmerki pa naj bo od 3 - 4 ure (glejte poglavje 4.2).
English: Breathing in the mist carries Ventavis to the lungs, where it can work most effectively in the artery between heart and lungs.
Slovenian: Z vdihavanjem meglice zdravila Ventavis pride le-to v pljuča, kjer lahko zelo učinkovito deluje na arterijo med srcem in pljuči.
English: Following intravenous infusion, the recovery of total radioactivity is 81 %, and the respective recoveries in urine and faeces are 68% and 12%.
Slovenian: Po intravenski infuziji je celokupna radioaktivnost 81 %, v seču 68 % in v blatu 12 %.
English: After intravenous administration, iloprost is extensively metabolised via ß-oxidation of the carboxyl side chain.
Slovenian: Po intravenski uporabi se iloprost presnavlja preko ß-oksidacije karboksilne stranske verige.
English: Bleeding events (mostly epistaxis and haemoptysis) were very common as expected in this patient population with a high proportion of patients taking anticoagulant co-medication.
Slovenian: Krvavitve (najpogosteje epistaksa in hemoptiza) so bile kot pričakovano zelo pogoste pri tistih populacijah bolnikov, v katerih velik delež bolnikov sočasno jemlje tudi antikoagulante.
English: Therefore, the same dosing recommendations as in patients with hepatic impairment (see above) are to be applied.
Slovenian: Zato glede odmerjanja veljajo ista priporočila kot za bolnike z okvaro jeter (glejte zgoraj).
English: In an intravenous study, results were obtained involving 8 patients suffering from liver cirrhosis.
Slovenian: V študiji intravenske uporabe so dobili izsledke pri 8 bolnikih z jetrno cirozo.
English: • Do NOT drink or swallow Ventavis solution.
Slovenian: • NE pijte raztopine Ventavis.
English: It imitates a natural substance in the body called prostacyclin.
Slovenian: Le-ta posnema delovanje naravne snovi v telesu, imenovane prostaciklin.
English: Following intravenous infusion, the apparent steady-state volume of distribution was 0.6 to 0.8 l/kg in healthy subjects.
Slovenian: Po intravenski infuziji je bil navidezni volumen porazdelitve v stanju dinamičnega ravnovesja pri zdravih osebah 0,6 do 0,8 l/kg.
English: If you have very severe kidney problems and require dialysis or if you have liver problems, your doctor will introduce you to Ventavis gradually and possibly prescribe fewer daily inhalations.
Slovenian: Če imate zelo hudo okvaro ledvic ali potrebujete dializo ter v primeru okvare jeter, vam bo zdravnik uvedel zdravljenje z zdravilom Ventavis postopoma in vam morda predpisal manj inhalacij na dan.
English: 108 of the patients included were diagnosed with primary pulmonary hypertension, 95 were diagnosed with secondary pulmonary hypertension of which 56 were associated with chronic thromboembolic disease, 34 with connective tissue disease (including CREST and scleroderma) and 4 were considered appetite suppressant medicinal product related.
Slovenian: Od vključenih bolnikov jih je 108 imelo diagnozo primarne pljučne hipertenzije, 95 pa diagnozo sekundarne pljučne hipertenzije, ki je bila pri 56 bolnikih povezana s kronično tromboembolijo, pri 34 z obolenjem vezivnih tkiv (vključno s CREST in sklerodermijo), pri 4 pa z zdravili za zmanjševanje apetita.
English: Should patients deteriorate on this treatment intravenous prostacyclin treatment should be considered.
Slovenian: Če bi se bolnikovo stanje ob tem zdravljenju poslabšalo, je treba razmisliti o možnosti intravenske aplikacije prostaciklina.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING INNER CARTON WITHOUT BLUE BOX
Slovenian: PODATKI NA ZUNANJI OVOJNINI NOTRANJA ŠKATLA BREZ MODREGA OKENCA
English: Your doctor may change the dosage.
Slovenian: Morda vam bo zdravnik spremenil odmerek zdravila.
English: • breathing difficulties (dyspnoea)
Slovenian: • težave z dihanjem (dispneja)
English: A dermal sensitisation (maximisation test) and an antigenicity study in guinea pigs showed no sensitising potential.
Slovenian: Kožna senzibilizacija (maksimizacijski test) in študije antigenosti pri morskih prašičkih niso pokazali senzibilizacijskega učinka.
English: In acute toxicity studies, single intravenous and oral doses of iloprost caused severe symptoms of intoxication or death (intravenous) at doses about two orders of magnitude above the intravenous therapeutic dose.
Slovenian: V študijah akutne toksičnosti so enkratni intravenski in peroralni odmerki iloprosta povzročili hude simptome zastrupitve ali smrt (intravenski) pri odmerkih, ki so približno dvakrat presegali intravenske terapevtske odmerke.
English: The increased occurrence of syncope can be related to the deterioration of the disease or insufficient effectiveness of the product (see section 4.4).
Slovenian: Večja pogostnost sinkope je lahko povezana z napredovanjem bolezni ali nezadostno učinkovitostjo zdravila (glejte poglavje 4.4).
English: Iloprost, the active substance of Ventavis, is a synthetic prostacyclin analogue.
Slovenian: Iloprost, učinkovina zdravila Ventavis, je sintetični analog prostaciklina.
English: Common (≥1/100 to <1/10)
Slovenian: zelo pogosti pogosti (≥ 1/100 do < 1/10)
English: Tell your doctor if you are taking any other medication because the combined effect with Ventavis may lower your blood pressure further (see below “Other medicines and Ventavis”).
Slovenian: Obvestite zdravnika, če jemljete katero koli drugo zdravilo, saj lahko sočasna uporaba z zdravilom Ventavis dodatno zniža krvni tlak (glejte spodaj, »Druga zdravila in zdravilo