FrancophonIA/ELRC3.0 huggingface dataset:
English: Studies in animals do not indicate direct harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3).
Croatian: Ispitivanja na životinjama ne ukazuju na izravne štetne učinke na trudnoću, embriofetalni razvoj, okot ni postnatalni razvoj (vidjeti dio 5.3).
English: You may require blood tests for several months after stopping treatment with Symtuza.
Croatian: Možda ćete morati obavljati krvne pretrage nekoliko mjeseci nakon završetka liječenja lijekom Symtuza.
English: Interaction trials with the components of Symtuza have only been performed in adults.
Croatian: Ispitivanja interakcija sa sastavnicama lijeka Symtuza provedena su samo u odraslih osoba.
English: People taking Symtuza may still develop infections or other illnesses associated with HIV infection.
Croatian: U ljudi koji uzimaju lijek Symtuza i dalje se mogu javljati infekcije ili druge bolesti povezane s HIV infekcijom.
English: If you forget to take Symtuza It is important not to miss a dose of Symtuza.
Croatian: Ako ste zaboravili uzeti lijek Symtuza Važno je da ne propustite uzeti niti jednu dozu lijeka Symtuza.
English: These are: - raised blood sugar and worsening of diabetes - muscle pain, tenderness or weakness.
Croatian: To su: - povišena razina šećera u krvi i pogoršanje šećerne bolesti - bol u mišićima, osjetljivost ili slabost mišića.
English: Via C. Janssen, Borgo San Michele
Croatian: Janssen, Borgo San Michele
English: The interaction profile of darunavir depends on whether ritonavir or cobicistat is used as a pharmacokinetic enhancer; therefore, there may be different recommendations for the use of darunavir with concomitant medicines.
Croatian: Interakcijski profil darunavira ovisi o tome je li kao farmakokinetički pojačivač korišten ritonavir ili kobicistat; stoga su moguće različite preporuke za istodobnu primjenu darunavira s drugim lijekovima.
English: Other severe side effects, seen up to 1 patient in 10, were diabetes, increased blood fat levels and symptoms of infection.
Croatian: Ostale teške nuspojave, zabilježene u do 1 na 10 bolesnika, bile su šećerna bolest, povišene razine masnoća u krvi i simptomi infekcije.
English: These findings were attributed to the immaturity of the liver enzymes and of the blood brain barrier.
Croatian: Ti su nalazi pripisani nezrelosti jetrenih enzima i krvno-moždane barijere.
English: Maximum plasma concentrations of darunavir, cobicistat, emtricitabine and tenofovir alafenamide were achieved at 4.00, 4.00, 2.00, and 1.50 hours after dosing, respectively.
Croatian: Vršne plazmatske koncentracije darunavira, kobicistata, emtricitabina i tenofoviralafenamida postignute su 4,00, 4,00, 2,00 odnosno 1,50 sati nakon primjene.
English: Your doctor will advise you how to deal with your symptoms or whether Symtuza must be stopped.
Croatian: Liječnik će Vam savjetovati kako ublažiti simptome ili trebate li prestati uzimati lijek Symtuza.
English: The EC50 values for emtricitabine were in the range of 0.0013 to 0.64 μM.
Croatian: Vrijednosti EC50 za emtricitabin kretale su se u rasponu od 0,0013 do 0,64 µM.
English: Based on animal studies, no effect on reproduction or fertility is expected with Symtuza.
Croatian: Temeljem ispitivanja na životinjama, ne očekuje se da će Symtuza utjecati na reprodukciju ili plodnost.
English: The digoxin dose should be carefully titrated to obtain the desired clinical effect while assessing the overall clinical state of the subject.
Croatian: Dozu digoksina treba pažljivo titrirati kako bi se postigao željeni klinički učinak, uz istodobno ocijenjivanje ukupnog kliničkog stanja bolesnika.
English: The Symtuza tablets are available in packs containing one bottle or three bottles per carton.
Croatian: Symtuza tablete su dostupne u pakiranjima koja sadrže jednu ili tri boce u kutiji.
English: At Week 36 M184M/I/V observed, conferring resistance to FTC.
Croatian: U 36. tjednu zabilježena je mutacija M184M/I/V, koja je dovela do rezistencije na FTC.
English: Psychiatric disorders common abnormal dreams
Croatian: Psihijatrijski poremećaji često neuobičajeni snovi
English: Treatment of overdose with Symtuza consists of general supportive measures, including monitoring of vital signs as well as observation of the clinical status of the patient.
Croatian: Liječenje predoziranja lijekom Symtuza sastoji se od općih potpornih mjera, koje uključuju praćenje vitalnih znakova i kliničkog statusa bolesnika.
English: Black
Croatian: Crna
English: Haemophiliac patients should, therefore, be made aware of the possibility of increased bleeding.
Croatian: Bolesnike s hemofilijom stoga treba upozoriti na mogućnost pojačanog krvarenja.
English: A long term carcinogenicity study of cobicistat in rats revealed tumourigenic potential specific for this species, that is regarded as of no relevance for humans.
Croatian: Dugoročno ispitivanje kancerogenosti kobicistata u štakora otkrilo je tumorogeni potencijal specifičan za tu vrstu koji se ne smatra značajnim za ljude.
English: If you have chronic hepatitis B or C infection, your doctor should check your blood tests more often because you have an increased chance of developing liver problems.
Croatian: Ako imate kroničnu infekciju hepatitisom B ili C, liječnik Vam treba češće kontrolirati krvnu sliku zbog povećane mogućnosti razvoja jetrenih tegoba.
English: Sulphonamide allergy
Croatian: Alergija na sulfonamide
English: Concentrations of these medicinal products may be increased when co-administered with Symtuza resulting in the potential for increased adverse events usually associated with these medicinal products.
Croatian: Koncentracije ovih lijekova mogu se povisiti kada se primjenjuju istodobno s lijekom Symtuza te potencijalno uzrokovati povećanje štetnih događaja koji su obično povezani s ovim lijekovima.
English: The following viral load values were observed for these subjects at Week 96: 54 copies/mL, 78 copies/mL, 111 copies/mL, 152 copies/mL, and 210 copies/mL.
Croatian: Za te je ispitanike opaženo sljedeće virusno opterećenje u 96. tjednu: 54 kopije/ml, 78 kopija/ml, 111 kopija/ml, 152 kopije/ml i 210 kopija/ml.
English: Clinical monitoring is recommended, as maintenance therapy may need to be adjusted in some patients.
Croatian: Preporučuje se kliničko praćenje zbog moguće potrebe za prilagodbom terapije održavanja u nekih bolesnika.
English: Tell your doctor immediately, if any of these apply to you.
Croatian: Odmah obavijestite svog liječnika ako se nešto od navedenog odnosi na Vas:
English: • if you notice any muscle or bone problems.
Croatian: • ako uočite bilo kakve tegobe s mišićima ili kostima.
English: These findings do not affect current national recommendations to use antiretroviral therapy in pregnant women to prevent vertical transmission of HIV.
Croatian: Ti nalazi ne utječu na važeće nacionalne preporuke za primjenu antiretrovirusne terapije u trudnica radi sprječavanja vertikalnog prijenosa HIV-a.
English: Darunavir has no effect on fertility or early embryonic development and DRV shows no teratogenic potential, at exposure levels below those at the recommended clinical dose in humans.
Croatian: Darunavir ne utječe na plodnost ni rani razvoj embrija te ne pokazuje teratogeni potencijal, pri razinama izloženosti ispod onih pri preporučenoj kliničkoj dozi u ljudi.
English: The safety and efficacy of Symtuza in patients co-infected with HIV-1 and hepatitis C virus (HCV) have not been established.
Croatian: Sigurnost i djelotvornost lijeka Symtuza u bolesnika istodobno zaraženih virusom HIV-1 i virusom hepatitisa C (HCV) nisu ustanovljene.
English: C]-darunavir trial in healthy volunteers showed that a majority of the radioactivity in plasma after a single 400/100 mg darunavir with ritonavir dose was due to the parent active substance.
Croatian: C]-darunavira u zdravih dobrovoljaca pokazalo je da većinu radioaktivnosti u plazmi nakon jednokratne doze darunavira pojačanog ritonavirom od 400/100 mg treba pripisati ishodišnoj djelatnoj tvari.
English: Patients were virologically suppressed for at least 2 months and no more than once had a viral load elevation above 50 HIV-1 RNA copies/mL during the year prior to enrollment.
Croatian: Bolesnici su bili virološki suprimirani barem 2 mjeseca te nisu više od jedanput imali porast virusnog opterećenja iznad 50 HIV-1 RNK kopija/mL tijekom godine prije uključenja.
English: Atorvastatin (10 mg once daily): atorvastatin AUC ↑ 290% atorvastatin Cmax ↑ 319% atorvastatin Cmin ND
Croatian: Atorvastatin (10 mg once daily): atorvastatin AUC ↑ 290% atorvastatin Cmax ↑ 319% atorvastatin Cmin NO
English: In vitro studies indicate that emtricitabine is not an inhibitor of human CYP enzymes.
Croatian: Ispitivanja in vitro pokazuju da emtricitabin nije inhibitor ljudskih CYP enzima.
English: The absolute bioavailability of a single 600 mg dose of darunavir alone was approximately 37% and increased to approximately 82% in the presence of 100 mg twice daily ritonavir.
Croatian: Apsolutna bioraspoloživost jednokratne doze darunavira od 600 mg iznosila je približno 37%, a povećala se na približno 82% u prisutnosti ritonavira u dozi od 100 mg dvaput na dan.
English: Keep Symtuza out of the sight and reach of children.
Croatian: Lijek Symtuza čuvajte izvan pogleda i dohvata djece.
English: Since darunavir and cobicistat are highly bound to plasma proteins, it is unlikely that they will be significantly removed by haemodialysis or peritoneal dialysis.
Croatian: Budući da se darunavir i kobicistat u velikoj mjeri vezuju za proteine u plazmi, nije vjerojatno da će se značajno ukloniti hemodijalizom ili peritonejskom dijalizom.
English: Amiodarone Dronedarone Ivabradine Quinidine Ranolazine
Croatian: Amiodaron Dronedaron Ivabradin Kinidin Ranolazin
English: When administration of HMG CoA reductase inhibitors and Symtuza is desired, it is recommended to start with the lowest dose and titrate up to the desired clinical effect while monitoring for safety.
Croatian: Kada je primjena inhibitora HMG-CoA reduktaze i lijeka Symtuza poželjna, preporučuje se započeti s najnižom dozom i povećavati je do postizanja željenog kliničkog učinka, pri čemu treba nadzirati sigurnost primjene.
English: • if you notice symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, tell your doctor immediately.
Croatian: • ako primijetite simptome kao što su mišićna slabost, slabost koja počinje u šakama i stopalima te se širi prema trupu, osjećaj lupanja srca, nevoljno drhtanje ili hiperaktivnost, odmah recite svom liječniku.
English: If Symtuza is co-administered with parenteral midazolam, it should be done in an intensive care unit or similar setting, which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Croatian: Ako se Symtuza primjenjuje istodobno s parenteralno primijenjenim midazolamom, treba to učiniti u jedinici intenzivnog liječenja ili sličnom okružju, u kojem se može osigurati strogi klinički nadzor i odgovarajuća medicinska skrb u slučaju depresije disanja i/ili dugotrajne sedacije.
English: HEPATITIS C VIRUS (HCV) DIRECT-ACTING ANTIVIRALS NS3-4A inhibitors
Croatian: ANTIVIRUSNI LIJEKOVI S IZRAVNIM DJELOVANJEM NA VIRUS HEPATITISA C (HCV) Inhibitori NS3-4A
English: Symtuza might increase the risk of bleeding.
Croatian: Symtuza može povećati rizik od krvarenja.
English: Name and address of the manufacturer(s) responsible for batch release Janssen-Cilag SpA
Croatian: Naziv i adresa proizvođača odgovornog za puštanje serije lijeka u promet Janssen-Cilag SpA
English: Third trimester of pregnancy N = 6
Croatian: Treće tromjesečje trudnoće (n=6)
English: Population pharmacokinetic analysis showed a slightly higher darunavir exposure (16.8%) in HIV-1 infected females compared to males.
Croatian: Populacijska farmakokinetička analiza pokazala je nešto višu izloženost darunaviru (16,8%) u žena nego u muškaraca zaraženih virusom HIV-1.
English: Week 96* D/C/F/TAF
Croatian: 96. tjedan* D/K/F/TAF
English: Your doctor might want to do some additional tests.
Croatian: Liječnik će možda provesti dodatne pretrage.
English: C]-darunavir with ritonavir showed that approximately 7.7% of the administered dose of darunavir is excreted in the urine unchanged.
Croatian: C]-darunavir s ritonavirom pokazali su da se približno 7,7% primijenjene doze darunavira izlučuje kroz mokraću u nepromijenjenom obliku.
English: - Atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin (to lower cholesterol levels).
Croatian: - atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin (za sniženje razina kolesterola).
English: Infrequently a rash may become severe or potentially life-threatening.
Croatian: Rijetko ovaj osip može postati težak ili po život opasan.
English: Symtuza is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and adolescents (aged 12 years and older with body weight at least 40 kg).
Croatian: Lijek Symtuza je indiciran za liječenje infekcije virusom humane imunodeficijencije tipa 1 (HIV-1) u odraslih i adolescenata (u dobi od 12 godina i starijih i tjelesne težine od najmanje 40 kg).
English: Daclatasvir Ledipasvir Sofosbuvir
Croatian: Daklatazvir Ledipasvir Sofosbuvir
English: Patients receiving Symtuza or any other antiretroviral therapy may continue to develop opportunistic infections and other complications of HIV infection, and therefore should remain under close clinical observation by physicians experienced in the treatment of patients with HIV associated diseases.
Croatian: U bolesnika koji primaju lijek Symtuza ili bilo koju drugu antiretrovirusnu terapiju mogu se i dalje javljati oportunističke infekcije i druge komplikacije povezane s HIV infekcijom pa bi zbog toga trebali ostati pod strogim kliničkim nadzorom liječnika koji imaju iskustva u liječenju bolesnika s bolestima povezanima s HIV-om.
English: Based on theoretical considerations, no clinically relevant interaction is expected.
Croatian: Na temelju teorijskih razmatranja, ne očekuje se klinički značajna interakcija.
English: Poly (vinyl alcohol)- partially hydrolysed Talc
Croatian: Poli(vinilni alkohol) - djelomično hidroliziran Talk
English: • Push the plastic screw cap down while turning it counter clockwise.
Croatian: • Pritisnite plastični zatvarač s navojem dok ga okrećete u smjeru suprotnom od kazaljke na satu.
English: Rosuvastatin (10 mg once daily): rosuvastatin AUC ↑ 93% rosuvastatin Cmax ↑ 277% rosuvastatin Cmin ND
Croatian: Rosuvastatin (10 mg jedanput na dan): rosuvastatin AUC ↑ 93% rosuvastatin Cmax ↑ 277% rosuvastatin Cmin NO
English: Co-administration of Symtuza and budesonide or fluticasone is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid side effects.
Croatian: Ne preporučuje se istodobna primjena lijeka Symtuza i budezonida ili flutikazona, osim ako moguća korist liječenja nadmašuje rizik od sistemskih nuspojava kortikosteroida.
English: ART-naïve patients The recommended dose regimen is one film-coated tablet of Symtuza once daily taken with food.
Croatian: Preporučeni režim doziranja je jedna filmom obložena tableta lijeka Symtuza jedanput dnevno, uzeta s hranom.
English: Week 48 D/C + F/TDF
Croatian: 48. tjedan D/K + F/TDF
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV disease and/or long-term exposure to combination antiretroviral therapy (CART).
Croatian: Iako se smatra da je etiologija multifaktorska (uključujući primjenu kortikosteroida, konzumaciju alkohola, tešku imunosupresiju, veći indeks tjelesne mase), slučajevi osteonekroze zabilježeni su osobito u bolesnika s uznapredovalom HIV bolešću i/ili dugotrajno izloženih kombiniranoj antiretrovirusnoj terapiji (KART).
English: p < 0.001 for all 4 lipid parameters when comparing D/C/F/TAF versus D/C + F/TDF at Week 48 No comparator data available beyond Week 48
Croatian: p < 0,001 za sva 4 lipidna parametra pri usporedbi D/K/F/TAF naspram D/K + F/TDF u 48. tjednu Nisu dostupni podaci za komparator nakon 48. tjedna
English: • if you have haemophilia.
Croatian: • ako imate hemofiliju.
English: The biotransformation of emtricitabine includes oxidation of the thiol moiety to form the 3'-sulfoxide diastereomers (approximately 9% of dose) and conjugation with glucuronic acid to form 2'-O-glucuronide (approximately 4% of dose).
Croatian: Biotransformacija emtricitabina uključuje oksidaciju tiolnog dijela molekule, pri čemu nastaju 3'-sulfoksid diastereomeri (približno 9% doze), i konjugaciju s glukuronskom kiselinom, pri čemu nastaje 2'-O-glukuronid (približno 4% doze).
English: Symtuza comes in bottles of 30 tablets (with a silica gel desiccant that must be kept in the bottle to help protect your tablets).
Croatian: Symtuza dolazi u bocama koje sadrže 30 tableta (sa silikagelom kao sredstvom za sušenje koje se mora čuvati u boci radi zaštite tableta).
English: Patients co-infected with HIV and HBV who discontinue Symtuza should be closely monitored with both clinical and laboratory follow-up for at least several months after stopping treatment.
Croatian: Bolesnike istodobno zaražene HIV-om i HBV-om koji prekinu primjenu lijeka Symtuza potrebno je pažljivo nadzirati uz kliničko i laboratorijsko praćenje najmanje nekoliko mjeseci nakon prekida liječenja.
English: The pharmacokinetics of emtricitabine have not been studied in patients with hepatic impairment; however, emtricitabine is not significantly metabolised by liver enzymes, so the impact of liver impairment should be limited.
Croatian: Farmakokinetika emtricitabina nije ispitivana u bolesnika s oštećenjem jetrene funkcije; međutim, emtricitabin se neznatno metabolizira putem jetrenih enzima, pa bi učinak oštećenja jetrene funkcije trebao biti ograničen.
English: What Symtuza contains
Croatian: Što lijek Symtuza sadrži
English: Emtricitabine can be removed by haemodialysis, which removes approximately 30% of the emtricitabine dose over a 3 hour dialysis period starting within 1.5 hours of emtricitabine dosing.
Croatian: Emtricitabin se može ukloniti hemodijalizom, pa se tijekom 3-satne dijalize započete unutar 1,5 sati nakon primjene emtricitabina uklanja približno 30% doze.
English: However, unbound darunavir concentrations were approximately 55% (Child-Pugh Class A) and 100% (Child-Pugh Class B) higher, respectively.
Croatian: Međutim, koncentracije nevezanog darunavira bile su približno 55% (Child-Pugh stadij A) odnosno 100%
English: Symtuza is an antiretroviral medicine used to treat infection with human immunodeficiency virus 1 (HIV-1).
Croatian: Symtuza je antiretrovirusni lijek koji se koristi za liječenje infekcije virusom humane imunodeficijencije tipa 1 (HIV-1).
English: For the treatment of pulmonary arterial hypertension Sildenafil Tadalafil
Croatian: Za liječenje plućne arterijske hipertenzije Sildenafil Tadalafil
English: Due to uncertainties regarding the rate of development of the human blood brain barrier and liver enzymes Symtuza should not be used in paediatric patients below 3 years of age.
Croatian: S obzirom na nepoznanice oko brzine razvoja krvno-moždane barijere i jetrenih enzima u ljudi, Symtuza se ne smije primjenjivati u pedijatrijskih bolesnika mlađih od 3 godine.
English: This recommendation is different from ritonavir-boosted darunavir.
Croatian: Ova se preporuka razlikuje od one za darunavir pojačan ritonavirom.
English: Symtuza must not be used with another antiviral medicine that contains a booster or another antiviral that requires boosting.
Croatian: Symtuza se ne smije uzimati s drugim antivirusnim lijekom koji sadrži pojačivač ili drugim antivirotikom kojemu je potrebno pojačanje.
English: Paroxetine Sertraline
Croatian: Paroksetin Sertralin
English: The data from these studies showed that the overall safety profile of components of Symtuza in paediatric patients aged 12 to < 18 years and weighing at least 40 kg was similar to that observed in the adult population (see section 5.1).
Croatian: Podaci iz tih ispitivanja pokazali su da je ukupan sigurnosni profil sastavnica lijeka Symtuza u pedijatrijskih bolesnika u dobi od 12 do < 18 godina i tjelesne težine od najmanje 40 kg bio sličan onome opaženom u odrasloj populaciji (vidjeti dio 5.1).
English: Any inflammatory symptoms should be evaluated and treatment instituted when necessary.
Croatian: Svaki upalni simptom treba ocijeniti i po potrebi uvesti liječenje.
English: Non-completer is failure imputation: patients who discontinued prematurely are imputed with a change equal to 0.
Croatian: Bolesnik koji nije završio ispitivanje zabilježen je kao neuspjeh: bolesnicima koji su prijevremeno prekinuli ispitivanje pripisana je promjena jednaka 0
English: Inflammation of the pancreas (pancreatitis) has been reported in up to 1 patient in 100.
Croatian: Upala gušterače (pankreatitis) prijavljena je u do 1 na 100 bolesnika.
English: If you do miss a dose:
Croatian: Ako ipak propustite dozu:
English: Pregnant or breast-feeding mothers should not take Symtuza.
Croatian: Trudnice ili dojilje ne smiju uzimati lijek Symtuza.
English: • if you have had problems with your liver, including hepatitis B or C infection.
Croatian: • ako ste već imali jetrenih tegoba, uključujući infekciju hepatitisom B ili C.
English: Tenofovir alafenamide was not mutagenic or clastogenic in conventional genotoxicity assays.
Croatian: Tenofoviralafenamid se nije pokazao mutagenim niti klastogenim u konvencionalnim ispitivanjima genotoksičnosti.
English: It selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus infected cells, thereby preventing the formation of mature infectious virus particles.
Croatian: Selektivno inhibira cijepanje HIV-om kodiranih Gag-Pol poliproteina u stanicama zaraženima virusom, sprječavajući tako nastanak zrelih infektivnih virusnih čestica.
English: ethinylestradiol AUC  30% ethinylestradiol Cmax  14% ethinylestradiol Cmin ND
Croatian: etinilestradiol AUC  30% etinilestradiol Cmax  14% etinilestradiol Cmin NO
English: Virologic response was defined as a decrease in plasma HIV-1 RNA viral load of at least 1.0 log10 versus baseline (see Table 7).
Croatian: Virološki odgovor definirao se kao smanjenje plazmatskog virusnog opterećenja HIV-1 RNK za najmanje 1,0 log10 u odnosu na početnu vrijednost (vidjeti Tablicu 7).
English: ANTIPSYCHOTICS/NEUROLEPTICS Perphenazine
Croatian: ANTIPSIHOTICI/NEUROLEPTICI Perfenazin
English: ANTIBIOTIC Clarithromycin
Croatian: ANTIBIOTICI Klaritromicin
English: The decreased susceptibility to darunavir of the emerging viruses in the selection experiment could not be explained by the emergence of these protease mutations.
Croatian: Smanjena osjetljivost na darunavir kod virusa nastalih tijekom pokusa izdvajanja nije se mogla objasniti nastankom tih mutacija proteaze.
English: • if you have had problems with your kidneys.
Croatian: • ako ste imali tegoba s bubrezima.
English: Reduced susceptibility to emtricitabine is associated with M184V/I mutations in HIV-1 RT.
Croatian: Smanjena osjetljivost na emtricitabin povezana je s mutacijama M184V/I u HIV-1 RT.
English: Patients using oestrogens as hormone replacement therapy should be clinically monitored for signs of oestrogen deficiency.
Croatian: U bolesnica koje koriste estrogene kao hormonsko nadomjesnu terapiju trebaju se klinički pratiti znakovi estrogenske deficijencije.
English: Some patients taking anti-HIV medicines may develop a bone disease called osteonecrosis (bone damage caused by loss of blood supply to the bone).
Croatian: U nekih bolesnika koji uzimaju lijekove protiv HIV-a može se razviti koštana bolest koja se zove osteonekroza (oštećenje kosti zbog prestanka opskrbe kosti krvlju).
English: Midazolam (oral) Triazolam
Croatian: Midazolam (peroralno) Triazolam
English: Therapy should be initiated by a physician experienced in the management of HIV-1 infection.
Croatian: Liječenje treba započeti liječnik s iskustvom u liječenju HIV-1 infekcije.