FrancophonIA/ELRC3.0 huggingface dataset:
English: The median (quartile 1, quartile 3) time to achieve haemoglobin correction (≥ 10.0 g/dL and ≥ 1.0 g/dL increase from baseline) was 5 weeks for both once every two week (3, 7 weeks) and once monthly dosing (3, 9 weeks).
Croatian: Medijan (1. kvartil, 3. kvartil) vremena do postizanja korekcije hemoglobina (povećanje za ≥ 10,0 g/dl i ≥ 1,0 g/dl od početne vrijednosti) iznosio je 5 tjedana kako za doziranje jednom svaka dva tjedna (3, 7 tjedana), tako i za doziranje jednom mjesečno (3, 9 tjedana).
English: Do not recycle the pre-filled pen or sharps disposal container or throw them into household rubbish.
Croatian: Nemojte reciklirati iskorištene brizgalice ili spremnik za odlaganje oštrih predmeta ili ih bacati u kućni otpad.
English: Contents of the pack and other information Instructions for injecting with the Aranesp pre-filled syringe
Croatian: Sadržaj pakiranja i druge informacije Upute za injiciranje lijeka Aranesp u napunjenoj štrcaljki
English: F Stretch or pinch your injection site to create a firm surface.
Croatian: F Rastegnite ili stegnite komad kože na mjestu injiciranja kako biste stvorili čvrstu površinu.
English: Keep this medicine out of the sight and reach of children.
Croatian: Ovaj lijeka čuvajte izvan pogleda i dohvata djece.
English: If you develop a serious rash or another of these skin symptoms, stop taking Aranesp and contact your doctor or seek medical attention immediately.
Croatian: Ako se razvije ozbiljan osip ili neki od navedenih simptoma na koži, prestanite uzimati Aranesp i obratite se Vašem liječniku ili odmah potražite liječničku pomoć.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 0.65 ml
Croatian: SADRŽAJ PO TEŽINI, VOLUMENU ILI DOZNOJ JEDINICI LIJEKA 0,65 ml
English: Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.
Croatian: Detaljne informacije o ovom lijeku dostupne su na internetskoj stranici Europske agencije za lijekove: http://www.ema.europa.eu
English: The MAH shall agree the final educational material with the national competent authority where the pre-filled pen is marketed.
Croatian: Nositelj odobrenja za stavljanje lijeka u promet dogovorit će konačne edukacijske materijale s nacionalnim nadležnim tijelom onih tržišta gdje se napunjena brizgalica prodaje.
English: Stroke was identified as an adverse reaction in an additional clinical study (TREAT, see section 5.1).
Croatian: Moždani udar je uočen kao nuspojava u dodatnom kliničkom ispitivanju (TREAT, vidjeti dio 5.1).
English: In the once weekly group, 75% of patients required dose reductions.
Croatian: U skupini koja je lijek primala jednom tjedno, kod 75% bolesnika bilo je potrebno smanjiti dozu.
English: • If there is blood, press a cotton ball or gauze pad on your injection site.
Croatian: • Ukoliko ima krvi, pritisnite pamučnu vatu ili jastučić gaze na mjesto injiciranja.
English: If you stop using Aranesp
Croatian: Ako prestanete primjenjivati Aranesp
English: After any dose or schedule adjustment the haemoglobin should be monitored every one or two weeks.
Croatian: Nakon svakog prilagođavanja doze ili rasporeda uzimanja, hemoglobin se mora pratiti svaki tjedan ili svaka 2 tjedna.
English: K Examine the injection site.
Croatian: B Pregledajte mjesto injiciranja
English: The recommended initial dose is 500 mcg (6.75 mcg/kg) given once every three weeks, or once weekly dosing can be given at 2.25 mcg/kg body weight.
Croatian: Preporučena početna doza je 500 μg (6,75 μg/kg) primijenjena jednom svaka 3 tjedna, ili se jednom tjedno može dati doza od 2,25 µg/kg tjelesne težine.
English: In patients with solid tumours or lymphoproliferative malignancies, if the haemoglobin value exceeds 12 g/dL (7.5 mmol/L), the dosage adaptation described in section 4.2 should be closely respected, in order to minimise the potential risk of thromboembolic events.
Croatian: Ako u bolesnika sa solidnim tumorima ili limfoproliferativnim malignim bolestima vrijednost hemoglobina prijeđe 12 g/dl (7,5 mmol/l), mora se točno pridržavati prilagodbe doze opisane u dijelu 4.2 kako bi se smanjio potencijalni rizik tromboembolijskih događaja.
English: It is important that you do not try to give the injection unless you or your caregiver has received training from your healthcare provider.
Croatian: Važno je da ne pokušavate dati injekciju ukoliko Vi sami ili Vaš skrbnik niste prošli obuku kod Vašeg zdravstvenog radnika.
English: Remember: If you have any problems, please do not be afraid to ask your doctor or nurse for help and advice.
Croatian: Zapamtite: ako imate bilo kakvih poteškoća, obratite se za pomoć i savjet svojem liječniku ili medicinskoj sestri.
English: This study was conducted in 705 anaemic patients with non-myeloid malignancies receiving multi-cycle chemotherapy.
Croatian: Ovo ispitivanje provedeno je na 705 anemičnih bolesnika koji su bolovali od nemijeloične maligne bolesti i primali više ciklusa kemoterapije.
English: Production of endogenous erythropoietin is impaired in patients with chronic renal failure and the primary cause of their anaemia is due to erythropoietin deficiency.
Croatian: Stvaranje endogenog eritropoetina smanjeno je u bolesnika s kroničnim zatajenjem bubrega pa je primarni uzrok njihove anemije manjak eritropoetina.
English: Convulsions have been reported in patients receiving Aranesp.
Croatian: Konvulzije su prijavljene kod bolesnika koji su primali Aranesp.
English: • Blood clots (thrombosis)
Croatian: • krvni ugrušci (tromboza)
English: Analysis of the individual components of the composite endpoints showed the following HR (95% CI): death 1.05 (0.92, 1.21), congestive heart failure (CHF) 0.89 (0.74, 1.08), myocardial infarction (MI) 0.96 (0.75, 1.23), stroke 1.92 (1.38, 2.68), hospitalisation for myocardial ischaemia 0.84 (0.55, 1.27), ESRD 1.02 (0.87, 1.18).
Croatian: Analiza individualnih komponenti kompozitnih ishoda je pokazala sljedeći HR (95% Cl); smrt 1,05 (0,92; 1,21), kongestivno zatajenje srca 0,89 (0,74; 1,08), infarkt miokarda 0,96 (0,75; 1,23), moždani udar 1,92 (1,38; 2,68), hospitalizacija zbog ishemije miokarda 0,84 (0,55; 1,27), terminalni stadij kroničnog zatajenja bubrega 1,02 (0,87; 1,18).
English: Solution for injection (injection) in pre-filled pen (SureClick).
Croatian: Otopina za injekciju (injekcija) u napunjenoj brizgalici (SureClick).
English: If you have chronic renal failure
Croatian: Ako imate kronično zatajenje bubrega
English: Following subcutaneous administration of 2.25 mcg/kg to adult cancer patients a mean peak concentration of 10.6 ng/mL (SD 5.9) of darbepoetin alfa was reached at a mean time of 91 hours (SD 19.7).
Croatian: Nakon supkutane primjene 2,25 μg/kg odraslim bolesnicima s rakom, postignuta je srednja vrijednost vršne koncentracije od 10,6 ng/ml (SD 5,9) u srednjem vremenu od 91 sat (SD 19,7).
English: Clinical studies have demonstrated that adult patients receiving r-HuEPO one, two or three times weekly may be converted to once weekly or once every other week Aranesp.
Croatian: Klinička ispitivanja pokazala su da odrasli bolesnici koji primaju r-HuEPO jednom, 2 ili 3 puta tjedno mogu prijeći na primjenu lijeka Aranesp jednom tjedno ili jednom svaka 2 tjedna.
English: In a phase 1 pharmacokinetic study, following intravenous administration, an approximate 25% difference between paediatric and adult patients in the area under the curve from time 0 to infinity (AUC[0-∞]) was observed; however, this difference was less than the 2-fold range in AUC(0-∞) observed for the paediatric patients.
Croatian: U farmakokinetičkom ispitivanju faze 1, nakon intravenske primjene, uočena je razlika od oko 25% između pedijatrijskih i odraslih bolesnika u području ispod krivulje u vremenu 0 do beskonačno (AUC[0-∞]).
English: These can appear as reddish target-like macules or circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals and eyes and can be preceded by fever and flu-like symptoms.
Croatian: Stevens-Johnsonov sindrom i toksična epidermalna nekroliza mogu se pojaviti kao crvene pjege nalik meti ili kružne mrlje, često s mjehurom u sredini, na trupu, ljuštenje kože, vrijed u ustima, grlu, nosu, spolovilu i očima, a mogu im prethoditi vrućica i simptomi nalik gripi.
English: Convulsions
Croatian: Konvulzije
English: Source: Includes 5 randomised, double-blind, active-controlled studies (970200, 970235, 980117, 980202, and
Croatian: Izvor: Uključuje 5 randomiziranih, dvostruko slijepih, aktivno kontroliranih ispitivanja (970200, 970235,
English: The results showed non-inferiority for the primary endpoint of overall survival with a median survival for darbepoetin alfa versus placebo of 9.5 and 9.3 months, respectively (stratified HR 0.92; 95% CI: 0.831.01).
Croatian: Rezultati su pokazali neinferiornost za primarnu mjeru ishoda ukupnog preživljenja s medijanom preživljenja za darbepoetin alfa od 9,5 mjeseci naspram placeba od 9,3 mjeseca (stratificirani HR 0,92; 95% CI: 0,83-1,01).
English: Per the Guideline on Summary of Product Characteristics (Revision 2, September 2009), frequency of ADRs identified in the post marketing setting was determined using the “Rule of three”.
Croatian: Prema Smjernicama o sažetku opisa svojstava lijeka (revizija 2, rujan 2009.), učestalost nuspojava uočenih nakon stavljanja lijeka u promet određena je primjenom "pravila trojke" (engl.
English: At the time of clinical data cutoff, the median progression free survival (PFS) per investigator assessment of disease progression was 7.4 months in each arm (HR 1.09, 95% CI: 0.99, 1.20), indicating the study objective was not met.
Croatian: U trenutku prekida prikupljanja kliničkih podataka, medijan preživljenja bez progresije bolesti (PFS, engl. progression free survival) prema procjeni istraživača o napredovanju bolesti iznosio je 7,4 mjeseca u svakoj skupini (HR 1,09; 95% CI: 0,99; 1,20), što ukazuje da cilj ispitivanja nije ostvaren.
English: For a more comfortable injection, leave the pre-filled syringe at room temperature for about 30 minutes before injecting.
Croatian: Za ugodniju primjenu, ostavite napunjenu štrcaljku na sobnoj temperaturi kroz oko 30 minuta prije injiciranja.
English: If you forget to use Aranesp
Croatian: Ako ste zaboravili primijeniti Aranesp
English: - Your doctor should try to keep your haemoglobin between 10 and 12 g/dL.
Croatian: Vaš hemoglobin između 10 i 12 g/dl.
English: Do not use Aranesp: - if you are allergic to darbepoetin alfa or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte uzimati Aranesp: - ako ste alergični na darbepoetin alfa ili neki drugi sastojak ovog lijeka (naveden u dijelu 6). - ako Vam je dijagnosticiran visoki krvni tlak koji nije kontroliran drugim lijekovima koje Vam je propisao liječnik.
English: Your doctor may decide that it is best for you or a carer to inject Aranesp.
Croatian: Liječnik može odlučiti da je za Vas najbolje da sami sebi dajete lijek ili da to čini Vaš skrbnik.
English: In CRF patients on haemodialysis, events of vascular access thrombosis (such as vascular access complication, arteriovenous fistula thrombosis, graft thrombosis, shunt thrombosis, arteriovenous fistula site complication, etc.) have been reported in post-marketing data.
Croatian: Kod bolesnika s kroničnim zatajenjem bubrega koji su na hemodijalizi, događaji vaskularne tromboze na mjestu primjene (kao što su komplikacija u vaskularnom pristupu, tromboza arteriovenske fistule, tromboza transplantata, tromboza šanta, komplikacija na mjestu arteriovenske fistule, itd.) prijavljeni su nakon stavljanja lijeka u promet.
English: b Stroke events includes PT haemorrhagic stroke, ischaemic stroke, cerebrovascular accident, and stroke in evolution.
Croatian: b Događaji moždanog udara uključuju sljedeće preporučene pojmove: hemoragijski moždani udar, ishemijski moždani udar, cerebrovaskularni inzult i moždani udar u razvoju.
English: Dosing should be titrated as necessary to maintain the haemoglobin target.
Croatian: Dozu se mora titrirati prema potrebi tako da se održi ciljni hemoglobin.
English: Incidence of adverse reactions from controlled clinical studies and post-marketing experience are:
Croatian: Incidencija nuspojava iz kontroliranih kliničkih ispitivanja i iskustva nakon stavljanja lijeka u promet je:
English: Your doctor will check that your haemoglobin does not exceed a certain level, as high haemoglobin concentrations could put you at risk of having a problem of the heart or the blood vessels and could increase risk of myocardial infarction, stroke and death.
Croatian: Liječnik će provjeriti da hemoglobin ne prelazi određenu granicu, jer zbog visokih koncentracija hemoglobina možete biti pod rizikom za nastanak problema sa srcem ili krvnim žilama i pod povećanim rizikom od infarkta srca, moždanog udara i smrti.
English: Aranesp is given as a single injection, either once a week or once every three weeks, under your skin.
Croatian: Aranesp se daje u obliku jedne injekcije, jednom tjedno ili jednom svaka tri tjedna potkožno.
English: • Keep the pre-filled pen and all medicines out of the reach of children.
Croatian: • Čuvajte napunjenu brizgalicu i sve lijekove izvan dohvata djece.
English: Note: After you remove the pre-filled pen from your skin, the needle will be automatically covered.
Croatian: Napomena: Nakon što odvojite brizgalicu od kože, žuti sigurnosni štitnik će automatski prekriti iglu.
English: This box containing 1 pre-filled pen, is part of a 4-multipack SureClick x4
Croatian: 1 napunjena brizgalica za jednokratnu uporabu Ova kutija sadrži 1 napunjenu brizgalicu, a dio je višestrukog pakiranja od 4 SureClick x 4
English: • Belly, except for a 5 cm (2-inch) area right around your belly button
Croatian: • Trbuh, osim u području od 5 cm (2 inča) oko pupka
English: Aranesp contains sodium
Croatian: Aranesp sadrži natrij
English: Important: Always keep the sharps disposal container out of the sight and reach of children.
Croatian: Važno: Uvijek držite spremnik za odlaganje oštrih predmeta izvan pogleda i dohvata djece.
English: Alternatively, in patients not on dialysis, the following initial doses can also be administered subcutaneously as a single injection: 0.75 mcg/kg once every two weeks or 1.5 mcg/kg once monthly.
Croatian: Alternativno, bolesnicima koji nisu na dijalizi također se mogu primijeniti sljedeće početne doze supkutano kao jedna injekcija: 0,75 μg/kg jedanput svaka dva tjedna ili 1,5 μg/kg jedanput mjesečno.
English: Therapy should be reinitiated at approximately 25% lower than the previous dose after haemoglobin levels fall to 12 g/dL (7.5 mmol/L) or below.
Croatian: Liječenje treba ponovo početi s otprilike 25% nižom dozom od prethodne nakon što vrijednost hemoglobina padne na 12 g/dl (7,5 mmol/l) ili niže.
English: It is important that you do not try to give yourself the injection unless you have received training from your doctor, nurse or pharmacist.
Croatian: Važno je da ne pokušavate sami sebi dati injekciju ukoliko niste prošli obuku kod svojeg liječnika, medicinske sestre ili ljekarnika.
English: Not known: frequency cannot be estimated from available data • Pure red cell aplasia (PRCA) - (anaemia, unusual tiredness, lack of energy)
Croatian: • izolirana aplazija crvenih krvnih stanica (PRCA) - (anemija, neuobičajeni umor, nedostatak energije)
English: If you want to use the same injection site, make sure it is not the same spot on the injection site you used for a previous injection.
Croatian: Ukoliko morate upotrijebiti isto mjesto injiciranja, provjerite da to ne bude baš ista točka na tom mjestu u koje ste injicirali prošli put.
English: If you have forgotten a dose of Aranesp, you should contact your doctor to discuss when you should inject the next dose.
Croatian: Ako ste zaboravili primijeniti dozu lijeka Aranesp, odmah se obratite svojem liječniku da Vas uputi kad trebate uzeti sljedeću dozu.
English: Put the original carton with any unused pre-filled pens back in the refrigerator.
Croatian: Vratite originalno pakiranje s neupotrebljenim napunjenim štrcaljkama natrag u hladnjak.
English: In a prospective, randomised double-blind, placebo-controlled study conducted in 314 lung cancer patients receiving platinum containing chemotherapy there was a significant reduction in transfusion requirements (p < 0.001).
Croatian: U prospektivnom, randomiziranom, dvostruko slijepom, placebom kontroliranom ispitivanju provedenom na 314 bolesnika s rakom pluća koji su primali kemoterapiju koja sadrži platinu postojalo je znatno smanjenje potreba za transfuzijom (p < 0,001).
English: Pooled post-hoc analyses of clinical studies of ESAs have been performed in chronic renal failure patients (on dialysis, not on dialysis, in diabetic and non-diabetic patients).
Croatian: Provedena je post-hoc analiza objedinjenih podataka iz kliničkih ispitivanja LSE-a u bolesnika s kroničnim zatajenjem bubrega (koji su na dijalizi, koji nisu na dijalizi, kod dijabetičara i ne-dijabetičara).
English: Aranesp is used to treat symptomatic anaemia that is associated with chronic renal failure (kidney failure) in adults and children.
Croatian: Aranesp se primjenjuje u liječenju simptomatske anemije povezane s kroničnim zatajenjem bubrega u odraslih osoba i djece.
English: In patients with a poor haemoglobin response to epoetins, alternative explanations for the poor response should be considered (see sections 4.2 and 5.1).
Croatian: U bolesnika s nedovoljnim odgovorom hemoglobina na epoetine, treba razmotriti druga objašnjenja za nedovoljan odgovor na liječenje (vidjeti dijelove 4.2 i 5.1).
English: Significantly fewer patients received RBC transfusions in the epoetin alfa plus SOC arm (5.8% versus 11.4%); however, significantly more patients had thrombotic vascular events in the epoetin alfa plus SOC arm (2.8% versus 1.4%).
Croatian: Znatno manji broj bolesnika primio je transfuziju crvenih krvnih stanica u skupini koja je primala epoetin alfa i standardnu zdravstvenu skrb (5,8% naspram 11,4%); međutim, značajno više bolesnika imalo je trombotske vaskularne događaje u skupini koja je primala epoetin alfa i standardnu zdravstvenu skrb (2,8% naspram 1,4%).
English: The pharmacokinetics of darbepoetin alfa in paediatric patients (2 to 16 years) with CRF who were either receiving or not receiving dialysis was assessed for sampling periods up to 2 weeks (336 hours) after one or two subcutaneous or intravenous doses.
Croatian: Farmakokinetika darbepoetina alfa kod pedijatrijskih bolesnika (2 do 16 godina) s kroničnim zatajenjem bubrega koji su bili na dijalizi i onih koji nisu, je ocijenjena za periode uzorkovanja do 2 tjedna (336 sati) nakon jedne ili dvije supkutane ili intravenske doze.
English: Aranesp is used to treat symptomatic anaemia in adult cancer patients with non-bone marrow cancers (non-myeloid malignancies) who are receiving chemotherapy.
Croatian: Aranesp se primjenjuje u liječenju simptomatske anemije u odraslih osoba koje boluju od raka koji podrijetlom nije iz koštane srži (nemijeloične maligne bolesti) i primaju kemoterapiju.
English: Meta-analysis of overall survival data produced a hazard ratio point estimate of 1.08 in favour of controls (95% CI: 0.99, 1.18; 42 trials and 8,167 patients).
Croatian: Metaanaliza podataka sveukupnog preživljenja dala je procjenu omjera rizika sveukupnog preživljenja od 1,08 u korist kontrolne skupine (95% CI: 0,99; 1,18; 42 ispitivanja i 8167 bolesnika).
English: Clinical data in paediatric patients has demonstrated that patients receiving r-HuEPO two or three times weekly may be converted to once weekly Aranesp, and those receiving r-HuEPO once weekly may be converted to once every other week Aranesp.
Croatian: Klinička ispitivanja su pokazala da pedijatrijski bolesnici koji primaju r-HuEPO 2 ili 3 puta tjedno mogu prijeći na primjenu lijeka Aranesp jednom tjedno, a oni koji primaju r-HuEPO jednom tjedno mogu prijeći na primjenu lijeka Aranesp jednom svaka 2 tjedna.
English: PHARMACEUTICAL FORM AND CONTENTS 1 single use vial
Croatian: OBLIK I SADRŽAJ 1 bočica za jednokratnu uporabu
English: The longer terminal half-life of darbepoetin alfa administered subcutaneously compared to intravenously is due to subcutaneous absorption kinetics.
Croatian: Poluvijek darbepoetina alfa primijenjenog supkutano, u usporedbi s intravenskom primjenom, je dulji zbog kinetike supkutane apsorpcije.
English: Rash/erythemac
Croatian: Osip/eritemc
English: Meta-analysis of overall survival data produced a hazard ratio point estimate of 1.06 in favour of controls (95% CI: 1.00, 1.12; 53 trials and 13,933 patients) and for the cancer patients receiving chemotherapy, the overall survival hazard ratio was 1.04 (95% CI: 0.97, 1.11; 38 trials and 10,441 patients).
Croatian: Metaanaliza sveukupnog preživljenja pokazala je procijenjeni omjer rizika od 1,06 u korist kontrola (95% CI: 1,00; 1,12; 53 ispitivanja i 13 933 bolesnika) i za bolesnike s rakom koji su primali kemoterapiju, ukupni omjer rizika preživljenja je bio 1,04 (95% CI: 0,97; 1,11; 38 ispitivanja i 10 441 bolesnika).
English: Patients were randomised to receive Aranesp at 500 mcg once every three weeks or 2.25 mcg/kg once weekly.
Croatian: Bolesnici su randomizirani za dobivanje 500 μg lijeka Aranesp jednom u 3 tjedna ili 2,25 μg/kg jednom tjedno.
English: In all cases, call your doctor or healthcare provider.
Croatian: U svim navedenim slučajevima, obratite se svom liječniku ili zdravstvenom radniku.
English: Treatment with Aranesp should be temporarily discontinued if haemoglobin levels exceed 13 g/dL (8.1 mmol/L).
Croatian: Liječenje lijekom Aranesp mora se privremeno prekinuti ako vrijednosti hemoglobina prijeđu 13 g/dl (8,1 mmol/l).
English: In patients with a poor haemoglobin response to Aranesp, alternative explanations for the poor response should be considered (see sections 4.4 and 5.1).
Croatian: U bolesnika s nedovoljnim odgovorom hemoglobina na Aranesp, treba razmotriti druga objašnjenja za nedovoljan odgovor na liječenje (vidjeti dijelove 4.4 i 5.1).
English: Hypersensitivitya
Croatian: Preosjetljivosta
English: Inject the prescribed dose subcutaneously as directed by your doctor, nurse or pharmacist.
Croatian: Injicirajte propisanu dozu potkožno kako Vas je uputio liječnik, medicinska sestra ili ljekarnik.
English: Your doctor, nurse or pharmacist will show you how to inject yourself with the pre-filled syringe.
Croatian: Liječnik, medicinska sestra ili ljekarnik će Vam pokazati kako ćete sami injicirati lijek.
English: Hypersensitivity reactions have been observed in cancer patients in post-marketing experience.
Croatian: Reakcije preosjetljivosti su primijećene kod bolesnika s rakom, nakon stavljanja lijeka u promet.
English: Once removed from the refrigerator and has reached room temperature (up to 25ºC) it must either be used within 7 days or disposed of.
Croatian: Jednom kad se izvadi iz hladnjaka i dostigne sobnu temperaturu (do 25°C), mora se upotrijebiti u roku 7 dana ili zbrinuti.
English: • Blood clots in a dialysis access
Croatian: • krvni ugrušci u pristupu za dijalizu
English: Aranesp is a sterile but unpreserved product.
Croatian: Aranesp je sterilan lijek, ali bez konzervansa.
English: • Fluid retention (oedema)
Croatian: • zadržavanje tekućine (edem)
English: • It is important that you do not try to give yourself the injection unless you have received training from your doctor or healthcare provider.
Croatian: • Važno je da ne pokušavate dati sebi injekciju ukoliko niste prošli obuku kod svojeg liječnika ili zdravstvenog radnika
English: PHARMACEUTICAL FORM AND CONTENTS 1 single use pre-filled syringe.
Croatian: OBLIK I SADRŽAJ 1 napunjena štrcaljka za jednokratnu uporabu.
English: The mean haemoglobin at week 28 for r-HuEPO and darbepoetin alfa was 11.1 (SD 1.4) g/dL and 11.1 (SD 1.1) g/dL, respectively.
Croatian: Srednja vrijednost hemoglobina u 28. tjednu za r-HuEPO bila je 11,1 (SD 1,4) g/dl, a za darbepoetin alfa 11,1 (SD 1,1) g/dl.
English: Instructions for injecting with the Aranesp pre-filled syringe This section contains information on how to give yourself an injection of Aranesp.
Croatian: Upute za injiciranje lijeka Aranesp u napunjenoj štrcaljki Ovo poglavlje sadrži upute o samoprimjeni injekcije lijeka Aranesp.