FrancophonIA/ELRC3.0 huggingface dataset:
English: In a 6-week, randomised, study of lithium and SEROQUEL XR versus placebo and SEROQUEL XR in adult patients with acute mania, the difference in YMRS mean improvement between the lithium add-on group and the placebo add-on group was 2.8 points and the difference in % responders (defined as 50% improvement from baseline on the YMRS) was 11% (79% in the lithium add-on group vs. 68% in the placebo add-on group).
Danish: I et 6-ugers randomiseret studie med lithium og Seroquel Prolong versus placebo og Seroquel Prolong hos voksne patienter med akut mani, var forskellen mellem den gennemsnitlige forbedring på YMRS mellem gruppen med lithium som tillægsbehandling og gruppen med placebo som tillægsbehandling 2,8 point, og forskellen i % respondenter (defineret som 50 % forbedring fra baseline på YMRS) var 11 % (79 % i gruppen med lithium som tillægsbehandling versus 68 % i gruppen med placebo som tillægsbehandling).
English: The mean plasma clearance of quetiapine was reduced by approximately 25% in subjects with severe renal impairment (creatinine clearance less than 30 ml/min/1.73 m2), but the individual clearance values are within the range for normal subjects.
Danish: Quetiapins gennemsnitlige plasmaclearance blev reduceret med ca. 25 % hos individer med svært nedsat nyrefunktion (kreatininclearance mindre end 30 ml/min/1,73 m2), men de individuelle clearanceværdier ligger inden for normalområdet.
English: Quetiapine should be discontinued in patients with a neutrophil count <1.0 X 109/L.
Danish: Quetiapin skal seponeres hos patienter med et neutrofiltal <1,0 x 109/l.
English: In a study examining the effects of food on the bioavailability of quetiapine, a high-fat meal was found to produce statistically significant increases in the Seroquel XR Cmax and AUC of approximately 50% and 20% respectively., It cannot be excluded that the effect of a high fat meal on the formulation may be larger.
Danish: I et studie hvor man undersøgte effekten af føde på biotilgængeligheden af quetiapin, blev der fundet, at et måltid med et højt fedtindhold medførte signifikante stigninger i Seroquel Prolongs Cmax og AUC på henholdsvis ca. 50 % og 20 %.
English: Clinical manifestations include hyperthermia, altered mental status, muscular rigidity, autonomic instability, and increased creatine phosphokinase.
Danish: Kliniske tegn er bl.a. hypertermi, bevidsthedsændring, muskelstivhed, autonome forstyrrelser og forhøjet kreatinfosfokinase.
English: Acute withdrawal symptoms such as insomnia, nausea, headache, diarrhoea, vomiting, dizziness, and irritability have been described after abrupt cessation of quetiapine.
Danish: Der er beskrevet akutte seponeringssymptomer såsom søvnløshed, kvalme, hovedpine, diarré, opkastning, svimmelhed og irritabilitet efter pludseligt ophør af quetiapin.
English: • High blood pressure medicines.
Danish: • Lægemidler mod forhøjet blodtryk.
English: In placebo-controlled studies in elderly patients with dementia-related psychosis, the incidence of cerebrovascular adverse events per 100 patient years was not higher in quetiapine-treated patients than in placebo-treated patients.
Danish: I placebo-kontrollerede studier med ældre patienter med demensrelateret psykose var hyppigheden af cerebrovaskulære bivirkninger pr. 100 patientår ikke højere hos quetiapin-behandlede patienter end hos placebo-behandlede patienter.
English: Long-term efficacy and safety in patients with MDD has not been evaluated as add-on therapy, however long-term efficacy and safety has been evaluated in adult patients as monotherapy (see below).
Danish: Den langtidsvarende virkning og sikkerhed af tillægsbehandling hos patienter med major depression er ikke blevet evalueret, men den langtidsvarende virkning og sikkerhed af monoterapi er blevet evalueret hos voksne patienter (se pkt.
English: Weight gain has been reported in patients who have been treated with quetiapine, and should be monitored and managed as clinically appropriate as in accordance with utilized antipsychotic guidelines (See Sections 4.8 and 5.1).
Danish: Det er blevet rapporteret vægtøgning hos patienter, som er blevet behandlet med quetiapin, og patienterne bør derfor monitoreres og behandles klinisk hensigtsmæssigt i overensstemmelse med de gældende retningslinjer for antipsykotisk behandling (se pkt.
English: In four placebo-controlled clinical trials, evaluating doses of Seroquel up to 800 mg/day for the treatment of moderate to severe manic episodes, two each in monotherapy and as combination therapy to lithium or divalproex, there were no differences between the Seroquel and placebo treatment groups in the incidence of EPS or concomitant use of anticholinergics.
Danish: I fire placebo-kontrollerede kliniske studier med doser af Seroquel på op til 800 mg/dag til behandling af moderate til svære maniske episoder (to som monoterapi og to som supplement til lithium eller divalproex) var der ingen forskelle mellem Seroquel og placebogrupperne i forekomsten af EPS eller samtidig anvendelse af anticholinerge stoffer.
English: (See section 4.4, Orthostatic hypotension ).
Danish: 4.4: Ortostatisk hypotension).
English: Tablet core: microcrystalline cellulose, sodium citrate, lactose monohydrate, magnesium stearate, hypromellose.
Danish: Tabletkerne: Mikrokrystallinsk cellulose, natriumcitrat, lactosemonohydrat, magnesiumstearat, hypromellose.
English: If you get any side effects, talk to your doctor or pharmacist.
Danish: Indberetning af bivirkninger til Sundhedsstyrelsen Hvis du oplever bivirkninger, bør du tale med din læge, sygeplejerske eller apoteket.
English: • Constipation, upset stomach (indigestion).
Danish: • Forstoppelse, irriteret mave (fordøjelsesbesvær).
English: In one long-term study (up to 2 years treatment) evaluating recurrence prevention in patients with manic, depressed or mixed mood episodes quetiapine was superior to placebo in increasing the time to recurrence of any mood event (manic, mixed or depressed), in patients with bipolar I disorder.
Danish: I et langtidsstudie (op til 2 års behandling) hvor man evaluerede forebyggelse af tilbagevendende sygdomsepisoder hos patienter med maniske, deprimerede eller blandede stemningsepisoder var quetiapin bedre end placebo til at øge tiden til tilbagevendende sygdomsepisoder for enhver stemningshændelse (manisk, blandet eller deprimeret) hos patienter med bipolar I lidelse.
English: In rats, pigment deposition in the thyroid gland has been observed; in cynomolgus monkeys thyroid follicular cell hypertrophy, a lowering in plasma T3 levels, decreased haemoglobin concentration and a decrease of red and white blood cell count have been observed; and in dogs lens opacity and cataracts.
Danish: Hos cynomolgus aber er der observeret hypertrofi af skjoldbruskkirtlens follikelceller, en nedsættelse af T3 plasmaniveauet, fald i hæmoglobinkoncentrationerne samt et fald i antallet af røde og hvide blodlegemer og hos hunde er der set linseuklarheder og katarakt.
English: Seroquel can be administered with or without food.
Danish: Seroquel kan tages med eller uden samtidig fødeindtagelse.
English: Constipation and intestinal obstruction have been reported with quetiapine (see section 4.8 Undesirable effects).
Danish: Forstoppelse og intestinal obstruktion er set med quetiapin (se pkt 4.8).
English: • Increased blood creatine phosphokinase (a substance from the muscles
Danish: • Forhøjet kreatinfosfokinase (et stof fra musklerne) i blodet.
English: (29) Based on adverse event reports of metabolic syndrome from all clinical trials with quetiapine.
Danish: (29) Baseret på rapporter om hændelser med metabolisk syndrom i alle kliniske studier med quetiapin.
English: In clinical trials for treatment of patients with bipolar depression and major depressive disorder, onset was usually within the first 3 days of treatment and was predominantly of mild to moderate intensity.
Danish: I kliniske studier på patienter med bipolar depression og unipolar depression indtrådte det sædvanligvis inden for de første 3 dages behandling, og intensiteten var hovedsagelig mild til moderat.
English: A meta analysis of placebo controlled clinical trials of antidepressant drugs in adult patients with psychiatric disorders showed an increased risk of suicidal behaviour with antidepressants compared to placebo in patients less than 25 years old.
Danish: En metaanalyse af placebokontrollerede kliniske studier med antidepressiva hos voksne patienter med psykiske lidelser viste en øget risiko for selvmordsadfærd ved antidepressiva sammenlignet med placebo hos patienter under 25 år.
English: Seroquel 3-Day Starterpack (Combined pack) contains 6 tablets Seroquel 25 mg and 2 tablets Seroquel 100 mg
Danish: Seroquel 3-dages startpakke (kombineret pakke) indeholder 6 Seroquel 25 mg tabletter og 2 Seroquel 100 mg tabletter.
English: Seroquel XR was dosed in the range of 400 to 800 mg/day and the mean dose was approximately 600 mg/day.
Danish: Seroquel Prolong blev doseret i intervallet 400 til 800 mg/dag og gennemsnitsdosis var ca. 600 mg/dag.
English: PHARMACEUTICAL FORM AND CONTENTS 8 film-coated tablets
Danish: LÆGEMIDDELFORM OG INDHOLDSMÆNGDE (PAKNINGSSTØRRELSE) 8 filmovertrukne tabletter
English: The rates of weight gain ≥ 7% of baseline body weight in the active arm vs. placebo were 17% vs. 2.5% in the schizophrenia and bipolar mania trials, and 12.5% vs. 6% in the bipolar depression trial.
Danish: Hyppigheden af vægtøgning ≥ 7 % af baseline-legemsvægt i den aktive arm versus placebo var 17 % hhv. 2,5 % i studierne med skizofreni og bipolar mani, og 12,5 % hhv. 6 % i studiet med bipolar depression.
English: The daily dose at the start of therapy is 300 mg on Day 1 and 600 mg on Day 2.
Danish: Ved behandlingsstart er den daglige dosis 300 mg på dag 1 og 600 mg på dag 2.
English: Shifts in eosinophils are defined as >1x 10^9 cells/L at any time.
Danish: Ændringer i eosinofiler defineres som >1x 10
English: 8 tablets
Danish: 8 tabletter
English: Seroquel data in combination with divalproex or lithium in acute moderate to severe manic episodes at 3 and 6 weeks is limited; however, combination therapy was well tolerated.
Danish: Data for Seroquel i kombination med divalproex eller lithium til behandling af akutte moderate til svære maniske episoder ved 3 og 6 uger er begrænset, dog var kombinationsbehandling veltolereret.
English: (20) Cases of suicidal ideation and suicidal behaviours have been reported during quetiapine therapy or early after treatment discontinuation (see Sections 4.4 and 5.1).
Danish: (20) Der er blevet rapporteret om selvmordstanker og selvmordsadfærd under behandlingen med quetiapin samt efter behandlingsophør (se pkt.
English: The incidence of somnolence was higher in the SEROQUEL XR with lithium add-on group (12.7%) compared to the SEROQUEL XR with the placebo add-on group (5.5%).
Danish: Forekomsten af døsighed var højere i gruppen med Seroquel Prolong og lithium som tillægsbehandling (12,7 %) sammenlignet med Seroquel Prolong og placebo som tillægsbehandling (5,5 %).
English: Other than the incidence of extrapyramidal symptoms (see section 4.8 and ‘Clinical Safety' below) the tolerability of Seroquel XR once daily in elderly patients was comparable to that seen in adults (aged 1865 years).
Danish: 4,8 og ”Klinisk sikkerhed” nedenfor) svarede tolerabiliteten for Seroquel Prolong givet én gang dagligt til ældre patienter til den, som sås hos voksne i alderen 18-65 år.
English: Hyperprolactina emia decreases in total T4 decreases in free T4 decreases in total T3 increases in TSH
Danish: Hyperprolakti næmi15, fald i totalt T4 fald i frit T4 , fald i totalt
English: Seroquel contains lactose which is a type of sugar.
Danish: Seroquel indeholder lactose, som er en sukkerart.
English: In the treatment of moderate to severe manic episodes, Seroquel demonstrated superior efficacy to placebo in reduction of manic symptoms at 3 and 12 weeks, in two monotherapy trials.
Danish: Til behandling af moderate til svære maniske episoder har Seroquel, i to monoterapistudier, vist bedre effekt end placebo på reduktion af maniske symptomer ved uge 3 og uge 12.
English: Other medicines and Seroquel XR Tell your doctor if you are taking or have recently taken any other medicines .
Danish: Brug af anden medicin sammen med Seroquel Prolong Fortæl det altid til lægen, hvis du tager anden medicin eller har gjort det for nylig.
English: Cellulose, microcrystalline Sodium citrate Lactose monohydrate Magnesium stearate Hypromellose 2208
Danish: Lactosemonohydrat Magnesiumstearat Hypromellose 2208
English: • Feeling weak.
Danish: • Svaghedsfølelse.
English: Treatment with Seroquel was initiated at 50 mg/day and on day 2 increased to 100 mg/day; subsequently the dose was titrated to a target dose (mania 400-600 mg/day; schizophrenia 400-800 mg/day) using increments of 100 mg/day given two or three times daily.
Danish: Behandlingen med Seroquel blev begyndt med 50 mg/dag og blev dag 2 øget til 100 mg/dag; derefter blev dosen titreret til en måldosis (mani 400-600 mg/dag; skizofreni 400-800 mg/dag) i trin på 100 mg/dag givet to eller tre gange daglig.
English: Pack sizes of 10, 30, 50, 60 and 100 tablets are registered for all strengths.
Danish: For alle styrker er der registreret pakningsstørrelser på 10, 30, 50, 60 og 100 tabletter.
English: Quetiapine does not produce dopamine D2-receptor supersensitivity after chronic administration.
Danish: Ved kronisk administrering forårsager quetiapin ikke supersensitivitet overfor dopamin D2-receptorer.
English: • Putting on weight.
Danish: • Vægtøgning.
English: Talk to your doctor or pharmacist before taking Seroquel if:
Danish: Kontakt lægen eller apotekspersonalet, før du tager Seroquel, hvis:
English: (4) As with other antipsychotics with alpha1 adrenergic blocking activity, quetiapine may commonly induce orthostatic hypotension, associated with dizziness, tachycardia and, in some patients, syncope, especially during the initial dose-titration period.
Danish: (4) Som for andre antipsykotika med α1-blokerende adrenerg aktivitet kan quetiapin specielt i den indledende dosistitreringsperiode inducere ortostatisk hypotension forbundet med svimmelhed, tachycardia, og hos nogle patienter besvimelse (se pkt.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING AND THE IMMEDIATE PACKAGING
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE OGPÅ DEN INDRE EMBALLAGE
English: Prolactin levels (patients < 18 years of age): >20 ug/L (>869.56 pmol/L) males; >26 ug/L (>1130.428 pmol/L) females at any time.
Danish: Prolaktinniveauer (patienter < 18 år): >20 ug/l (>869,56 pmol/l) hankøn; >26 ug/l (>1130,428 pmol/l) hunkøn ved ethvert tidspunkt.
English: Tablet Strength
Danish: Tabletstyrke
English: • The active substance is quetiapine.
Danish: - Aktivt stof: quetiapin.
English: Pack sizes of 20, 30, 50, 60 and 100 tablets are registered for all strengths.
Danish: For alle styrker er der registreret pakningsstørrelser på 20, 30, 50, 60 og 100 tabletter.
English: (22) Decreased haemoglobin to ≤13 g/dL (8.07 mmol/L) males, ≤12 g/dL (7.45 mmol/L) females on at least one occasion occurred in 11% of quetiapine patients in all trials including open label extensions.
Danish: (22) Nedsat hæmoglobin til ≤13 g/dl (8,07 mmol/l) hos mænd, ≤12 g/dl (7,45 mmol/l) hos kvinder ved mindst en lejlighed blev observeret hos 11 % of quetiapin-patienterne i alle studier, herunder openlabel-forlængelserne.
English: Quetiapine is not recommended for use in children and adolescents below 18 years of age, due to a lack of data to support use in this age group.
Danish: Quetiapin anbefales ikke til brug hos børn og unge under 18 år på grund af manglende data til støtte for brugen i denne aldersgruppe.
English: • Keep this medicine out of the reach and sight of children.
Danish: • Opbevar lægemidlet utilgængeligt for børn.
English: • Dizziness or a severe sense of feeling sleepy.
Danish: • bliver svimmel eller pludseligt føler dig meget søvnig.
English: Also caution should be exercised when quetiapine is prescribed either with medicines known to increase QT interval, or with concomitant neuroleptics, especially in the elderly, in patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalaemia or hypomagnesaemia (see section 4.5).
Danish: Forsigtighed bør også udvises, når quetiapin ordineres enten sammen med lægemidler, der er kendt for at øge QT-intervallet, eller med samtidige neuroleptika, specielt hos ældre, hos patienter med medfødt langt QT-syndrom, hjerteinsufficiens, hjertehypertrofi, hypokalæmi eller hypomagnesæmi (se pkt.
English: Depending on the clinical response and tolerability of the individual patient, the dose may be adjusted within the range 150 to 750 mg/day.
Danish: Afhængigt af det kliniske respons og tolerabiliteten hos den enkelte patient kan dosis justeres i intervallet fra 150 - 750 mg/dag.
English: Do not take a double dose to make up for a forgotten tablet.
Danish: Hvis det er tæt på at være tid til den næste dosis, så vent bare indtil da. Du må ikke tage en dobbeltdosis som erstatning for den glemte tablet.
English: 100 blisters of 1 tablet
Danish: 100 blisterkort a 1 tablet
English: The mean plasma clearance of quetiapine was reduced by 30-50% in elderly subjects when compared to younger patients.
Danish: Quetiapins gennemsnitlige plasmaclearance var reduceret med 30 %-50 % hos ældre, sammenlignet med yngre patienter.
English: Tell your doctor immediately if you experience any of the following after taking Seroquel::
Danish: Tal med din læge med det samme, hvis du oplever følgende efter at have taget Seroquel:
English: The pharmacokinetics of lithium were not altered when co-administered with quetiapine.
Danish: Lithiums farmakokinetik ændredes ikke ved samtidig administrering af quetiapin.
English: Also caution should be exercised when quetiapine is prescribed either with medicines known to increase QT interval or with concomitant neuroleptics, especially in the elderly, in patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalaemia or hypomagnesaemia (see section 4.5).
Danish: Forsigtighed bør også udvises, når quetiapin ordineres enten sammen med lægemidler, der er kendt for at øge QTintervallet eller med samtidig neuroleptika, specielt hos ældre, hos patienter med medfødt lang QT syndrom, hjerteinsufficiens, hjertehypertrofi, hypokalæmi eller hypomagnesæmi (se pkt.
English: (17) HDL cholesterol: <40 mg/dL (1.025 mmol/L) males; <50 mg/dL (1.282 mmol/L) females at any time.
Danish: (17) HDL-kolesterol: <40 mg/dl (1,025 mmol/l) hankøn; <50 mg/dl (1,282 mmol/l) hunkøn ved ethvert tidspunkt.
English: INFORMATION IN BRAILLE Seroquel 100 mg (or 150 mg, or 200 mg or 300 mg)
Danish: INFORMATION I BRAILLE-SKRIFT Seroquel 100 mg (eller 150 mg, 200 mg eller 300 mg)
English: Quetiapine should be used with caution in patients at risk for aspiration pneumonia.
Danish: Quetiapin bør anvendes med forsigtighed hos patienter med risiko for aspirationspneumoni.
English: A 6-week, randomised, study of lithium and SEROQUEL XR versus placebo and SEROQUEL XR in adult patients with acute mania indicated that the combination of SEROQUEL XR with lithium leads to more adverse events (63% versus 48% in SEROQUEL XR in combination with placebo).
Danish: Et randomiseret 6-ugers studie med lithium og Seroquel Prolong versus placebo og Seroquel Prolong hos voksne patienter med akut mani indikerede, at kombinationen af Seroquel Prolong og lithium medfører flere bivirkninger (63 % versus 48 % ved Seroquel Prolong i kombination med placebo).
English: Bipolar Disorder
Danish: Bipolar lidelse
English: For more convenient dosing, patients who are currently being treated with divided doses of immediate release Seroquel tablets may be switched to Seroquel XR at the equivalent total daily dose taken once daily.
Danish: Et forenklet doseringsregime kan opnås ved, at patienter som bliver behandlet med Seroquel tabletter 2 gange daglig skiftes til Seroquel Prolong ved ækvivalente totaldoser indtaget en gang daglig.
English: As with other antipsychotics, Seroquel should be used with caution in the elderly, especially during the initial dosing period.
Danish: Seroquel bør, som andre antipsykotika anvendes med forsigtighed hos ældre, især i den indledende doseringsperiode.
English: The class of medicines to which Seroquel belongs can cause heart rhythm problems, which can be serious and in severe cases may be fatal.
Danish: Den gruppe af lægemidler, som Seroquel tilhører, kan give problemer med hjerterytmen, som kan være alvorlig og i værste fald medføre døden.
English: Based on individual patient evaluation, if dose increase to 300 mg/day is required this should not be prior to Day 22 of treatment.
Danish: Dosis kan øges til 300 mg/dag, hvis dette vurderes nødvendigt efter en individuel evaluering af patienten, men denne dosis bør ikke gives før dag 22 i behandlingsforløbet.
English: Seroquel 4-Day Starterpack contains 6 tablets Seroquel 25 mg, 3 tablets Seroquel 100 mg and 1 tablet Seroquel 200 mg
Danish: Seroquel 4-dages startpakke indeholder 6 Seroquel 25 mg tabletter, 3 Seroquel 100 mg tabletter og 1 Seroquel 200 mg tablet.
English: Patients with rare hereditary problems of galactose intolerance, the lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicine.
Danish: Bør ikke anvendes til patienter med arvelig galactoseintolerans, en særlig form for hereditær lactasemangel (lapp lactase deficiency) eller glucose/galactosemalabsorption.
English: • A condition (called “metabolic syndrome”) where you may have a combination of 3 or more of the following: an increase in fat around your abdomen, a decrease in “good cholesterol” (HDL-C), an increase in a type of fat in your blood called triglycerides, high blood pressure and an increase in your blood sugar.
Danish: • En tilstand (kaldet metabolisk syndrom), hvor du kan have en kombination af 3 eller flere af følgende bivirkninger: Øget fedt rundt omkring maven, et nedsat indhold af ”godt kolesterol”
English: For 100 mg, 150 mg, 200 mg and 300 mg tablets pack sizes of 10, 90 are registered.
Danish: For 100 mg, 150 mg, 200 mg og 300 mg er der registreret pakningsstørrelser på 10 og 90.
English: Neuroleptic malignant syndrome hypothermia
Danish: Malignt neuroleptikasy ndrom hypotermi
English: The frequencies of adverse events are ranked according to the following: Very common (≥1/10), common
Danish: Bivirkningshyppighederne er inddelt som følger: Meget almindelig (≥ 1/10), almindelig (≥ 1/100
English: • Increases in the amount of the hormone prolactin in the blood.
Danish: • Stigninger i mængden af hormonet prolaktin i blodet.
English: 1 blister containing 6 x 25 mg and 2 x 100 mg tablets
Danish: 1 blisterkort indeholdende 6 x 25 mg samt 2 x 100 mg tabletter
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS BLISTER FOIL 4-Day starter pack
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS BLISTERFOLIE - 4-dages startpakke
English: Antidepressant effect was seen at 150 and 300 mg/day in shortterm trials as add-on therapy (with amitriptyline, bupropion, citalopram, duloxetine, escitalopram, fluoxetine, paroxetine, sertraline and venlafaxine - see Section 5.1) and at 50 mg/day in short-term monotherapy trials.
Danish: I korttidsstudier blev den antidepressive virkning observeret ved 150 og 300 mg daglig, når lægemidlet blev givet som supplerende behandling (i kombination med amitriptylin, bupropion, citalopram, duloxetin, escitalopram, fluoxetin, paroxetin, sertralin og venlafaxin - se pkt.
English: (6) Fasting blood glucose ≥126 mg/dL(≥7.0 mmol/L) or a non fasting blood glucose ≥200 mg/dL (≥11.1 mmol/L) on at least one occasion.
Danish: (6) Mindst ét tilfælde af fastende blodglucose ≥126 mg/dl (≥7,0 mmol/l) eller ikke fastende blodglucose ≥200 mg/dl (≥11,1 mmol/l).
English: If you suddenly stop taking Seroquel, you may be unable to sleep (insomnia), or you may feel sick (nausea), or you may experience headache, diarrhoea, being sick (vomiting), dizziness or irritability.
Danish: Hvis du pludselig stopper med at tage Seroquel, kan det være, at du får svært ved at sove, får kvalme eller hovedpine, diarré, opkastning, bliver svimmel eller irritabel.