FrancophonIA/ELRC3.0 huggingface dataset:
English: A study conducted in seven normal healthy volunteers showed that cimetidine, administered as 400 mg twice daily, increased metformin systemic exposure (AUC) by 50% and Cmax by 81%.
Croatian: Ispitivanje provedeno sa sedam normalnih zdravih dobrovoljaca pokazalo je da cimetidin u dozi od 400 mg dvaput na dan povećava sustavnu izloženost metforminu (AUC) za 50%, a Cmax za 81%.
English: The safety and efficacy of Xigduo in patients with type 1 diabetes have not been established and Xigduo should not be used for treatment of patients with type 1 diabetes.
Croatian: Sigurnost i djelotvornost lijeka Xigduo u bolesnika sa šećernom bolešću tipa 1 nisu ustanovljene te se Xigduo ne smije primjenjivati u liječenju bolesnika sa šećernom bolešću tipa 1.
English: The renal pelvic and tubular dilatations observed in juvenile animals did not fully reverse within the approximate 1-month recovery period.
Croatian: Proširenje bubrežne nakapnice i tubula primijećeno u mladih životinja nije se u potpunosti povuklo u razdoblju oporavka u trajanju od približno mjesec dana.
English: In a number of cases, the presentation of the condition was atypical with only moderately increased blood glucose values, below 14 mmol/L (250 mg/dL).
Croatian: U brojnim slučajevima stanje se očitovalo atipično, uz samo umjereno povišene vrijednosti glukoze u krvi, ispod 14 mmol/l (250 mg/dl).
English: If you stop taking Xigduo
Croatian: Ako prestanete uzimati Xigduo
English: SGLT2 is the predominant transporter responsible for reabsorption of glucose from the glomerular filtrate back into the circulation.
Croatian: SGLT2 je glavni prijenosnik odgovoran za reapsorpciju glukoze iz glomerularnog filtrata natrag u krvotok.
English: In case of intercurrent conditions that may lead to volume depletion (e.g. gastrointestinal illness), careful monitoring of volume status (e.g. physical examination, blood pressure measurements, laboratory tests including haematocrit and electrolytes) is recommended.
Croatian: U bolesnika u kojih istodobno postoje stanja koja mogu dovesti do deplecije volumena (npr. gastrointestinalne bolesti) preporučuje se pažljivo praćenje stanja volumena (npr. fizikalni pregled, mjerenje krvnog tlaka, laboratorijske pretrage, uključujući određivanje vrijednosti hematokrita i elektrolita).
English: Stop taking Xigduo for a short time if you have a condition that may be associated with dehydration (significant loss of body fluids) such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal.
Croatian: Prestanite nakratko uzimati Xigduo ako imate stanje koje može biti povezano s dehidracijom (značajan gubitak tjelesnih tekućina) kao što je jako povraćanje, proljev, vrućica, izloženost toplini ili ako pijete manje tekućine nego obično.
English: Use in patients at risk for volume depletion and/or hypotension Due to its mechanism of action, dapagliflozin increases diuresis which may lead to the modest decrease in blood pressure observed in clinical studies (see section 5.1).
Croatian: Primjena u bolesnika u kojih postoji rizik od deplecije volumena i/ili hipotenzije Zbog svog mehanizma djelovanja dapagliflozin pojačava diurezu, što može dovesti do blagog sniženja krvnog tlaka, koje je opaženo u kliničkim ispitivanjima (vidjeti dio 5.1).
English: Xigduo is used for a type of diabetes called “type 2 diabetes” in adult patients (aged 18 years and older) and usually occurs when you are older.
Croatian: Xigduo se primjenjuje za liječenje jedne vrste šećerne bolesti koja se naziva „šećerna bolest tipa 2“ u odraslih bolesnika (u dobi od 18 ili više godina), koja se obično javlja u starijoj dobi.
English: In case of dehydration (severe diarrhoea or vomiting, fever or reduced fluid intake), Xigduo should be temporarily discontinued and contact with a health care professional is recommended.
Croatian: U slučaju dehidracije (teški proljev ili povraćanje, vrućica ili smanjen unos tekućine), potrebno je privremeno prekinuti primjenu lijeka Xigduo i preporučuje se obratiti se zdravstvenom radniku.
English: If Fournier's gangrene is suspected, Xigduo should be discontinued and prompt treatment (including antibiotics and surgical debridement) should be instituted.
Croatian: Ako se sumnja na Fournierovu gangrenu, potrebno je prekinuti uzimanje lijeka Xigduo te hitno započeti s liječenjem (uključujući antibiotike i kirurški debridman).
English: Risk of volume depletion with dapagliflozin should also be taken into account (see sections 4.4 and 5.2).
Croatian: U obzir treba uzeti i rizik od deplecije volumena kod primjene dapagliflozina (vidjeti dijelove 4.4 i 5.2).
English: If you forget to take Xigduo
Croatian: Ako ste zaboravili uzeti Xigduo
English: Patients with baseline HbA1c ≥ 9%
Croatian: Bolesnici s početnom vrijednošću HbA1c ≥ 9%
English: For study results with respect to combination of therapies, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4.4, 4.5 and 5.1.
Croatian: Za rezultate ispitivanja koji se odnose na primjenu u kombinaciji s drugim lijekovima, učinke na regulaciju glikemije i kardiovaskularne događaje te ispitivane populacije vidjeti dijelove 4.4, 4.5 i 5.1.
English: Xigduo may cause a very rare, but very serious side effect called lactic acidosis, particularly if your kidneys are not working properly.
Croatian: Xigduo može uzrokovati vrlo rijetku, ali vrlo ozbiljnu nuspojavu koja se naziva laktacidoza, osobito ako Vam bubrezi ne rade ispravno.
English: In faeces, approximately 15% of the dose was excreted as parent drug.
Croatian: U fecesu je približno 15% doze izlučeno u obliku ishodišnog spoja.
English: OUTER CARTON - PART OF MULTIPACK - WITH BLUE BOX
Croatian: VANJSKA KUTIJA - DIO VIŠESTRUKOG PAKIRANJA - S PLAVIM OKVIROM
English: The meal resulted in a delay of 1 to 2 hours in the peak concentrations and a decrease in the maximum plasma concentration of 29% of dapagliflozin and 17% of metformin.
Croatian: Obrok je odgodio je postizanje vršnih koncentracija za 1 do 2 sata te smanjio maksimalne koncentracije dapagliflozina u plazmi za 29%, a metformina za 17%.
English: In active- and placebo-controlled clinical trials (dapagliflozin, N=5936, All control, N=3403), the frequency of rash was similar for dapagliflozin (1.4%) and all control (1.4%), respectively.
Croatian: U kliničkim ispitivanjima kontroliranim aktivnim lijekom i placebom (dapagliflozin, N=5936, sve kontrole, N=3403), učestalost osipa bila je slična za dapagliflozin (1,4%) i sve kontrole (1,4%).
English: Lactic acidosis is a medical emergency and must be treated in hospital.
Croatian: Laktacidoza je hitno medicinsko stanje koje se mora liječiti u bolnici.
English: • Metformin is contraindicated in patients with GFR of < 30 mL/min and should be temporarily discontinued in the presence of conditions that alter renal function (see section 4.3).
Croatian: • Metformin je kontraindiciran u bolesnika s GFR<30 ml/min i njegovu je primjenu potrebno privremeno prekinuti ako su prisutna stanja koja mijenjaju funkciju bubrega (vidjeti dio 4.3).
English: The difference in treatment effect was driven by hospitalisation for heart failure, with no difference in cardiovascular death (Figure 2).
Croatian: Razlika u učinku liječenja prvenstveno proizlazi iz razlike u hospitalizacijama zbog zatajenja srca, dok u stopi smrti zbog kardiovaskularnih uzroka nije bilo razlike (Slika 2).
English: • Metformin works mainly by inhibiting glucose production in the liver.
Croatian: • Metformin djeluje uglavnom tako da sprječava proizvodnju glukoze u jetri.
English: Symptoms include stomach pain, fast and deep breathing, sleepiness or your breath developing an unusual fruity smell.
Croatian: Simptomi uključuju bol u trbuhu, ubrzano i duboko disanje, pospanost ili Vam dah ima neobičan voćni miris.
English: • Your doctor may ask you to take this medicine on its own or together with other medicines to treat diabetes.
Croatian: • Liječnik može zatražiti da uzimate samo ovaj lijek ili da ga uzimate s drugim lijekovima za liječenje šećerne bolesti.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Xigduo in all subsets of the paediatric population in the treatment of type 2 diabetes (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove izuzela je obvezu podnošenja rezultata ispitivanja lijeka Xigduo u svim podskupinama pedijatrijske populacije u liječenju šećerne bolesti tipa 2 (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: This glucose excretion (glucuretic effect) is observed after the first dose, is continuous over the 24-hour dosing interval and is sustained for the duration of treatment.
Croatian: To je izlučivanje glukoze (glikozurija) vidljivo nakon prve doze, kontinuirano traje tijekom 24-satnog doznog intervala i održava se za cijelog trajanja liječenja.
English: Patients should be alerted to the risk of hypoglycaemia when this medicinal product is used in combination with other glucose-lowering medicinal products known to cause hypoglycaemia.
Croatian: Bolesnike treba upozoriti na rizik od hipoglikemije kod primjene ovog lijeka u kombinaciji s drugim lijekovima koji snižavaju razinu glukoze za koje se zna da uzrokuju hipoglikemiju.
English: It is unknown whether this medicinal product or dapagliflozin (and/or its metabolites) are excreted in human milk.
Croatian: Nije poznato izlučuju li se ovaj lijek ili dapagliflozin (i/ili njegovi metaboliti) u majčino mlijeko u ljudi.
English: Gastrointestinal symptoms such as nausea, vomiting, diarrhoea, abdominal pain and loss of appetite occur most frequently during initiation of therapy and resolve spontaneously in most cases.
Croatian: Gastrointestinalni simptomi poput mučnine, povraćanja, proljeva, boli u abdomenu i gubitka teka, najčešće se javljaju na početku liječenja, a u većini se slučajeva spontano povlače.
English: These symptoms could be a sign of “diabetic ketoacidosis” - a rare but serious, sometimes life-threatening problem you can get with diabetes because of increased levels of “ketone bodies” in your urine or blood, seen in tests.
Croatian: Ovi simptomi mogu biti znak „dijabetičke ketoacidoze“rijetkog ali ozbiljnog, ponekad i opasnog po život problema koji se može javiti uz šećernu bolest zbog povišenih razina „ketonskih tijela“ u mokraći ili krvi, što je vidljivo u nalazima pretraga.
English: 14, 28, 56 and 60 film-coated tablets in non-perforated blisters.
Croatian: 14, 28, 56 i 60 filmom obloženih tableta u neperforiranim blisterima.
English: The effect of this medicinal product or dapagliflozin on fertility in humans has not been studied.
Croatian: Nisu ispitivani učinci ovog lijeka ili dapagliflozina na plodnost u ljudi.
English: Most patients (98%) used one or more diabetic medications at baseline, including metformin (82%), insulin (41%) and sulfonylurea (43%).
Croatian: Većina je bolesnika (98%) na početku ispitivanja uzimala jedan ili više antidijabetika, uključujući metformin (82%), inzulin (41%) i sulfonilureju (43%).
English: • If renal function falls persistently below GFR 45 mL/min, treatment should be discontinued.
Croatian: • Ako se bubrežna funkcija pogorša te je kontinuirano ispod vrijednosti GFR 45 ml/min, liječenje treba prekinuti.
English: Major adverse cardiovascular events
Croatian: Veliki kardiovaskularni štetni događaji
English: • Dehydration: loss of too much fluid from your body, seen uncommonly (may affect up to 1 in 100 people).
Croatian: • Dehidracija: prekomjerni gubitak tekućine iz tijela, što je manje česta nuspojava (može se javiti u do 1 na 100 osoba).
English: Clinically relevant glycaemic effects were sustained in long-term extensions up to 104 weeks.
Croatian: Ti klinički značajni učinci na glikemiju održali su se u dugoročnim nastavcima ispitivanja do 104. tjedna.
English: Figure 2: Treatment effects for the primary composite endpoints and their components, and the secondary endpoints and components
Croatian: Slika 2: Učinci liječenja na primarne objedinjene mjere ishoda i njihove sastavnice te na sekundarne mjere ishoda i njihove sastavnice
English: Gender The mean dapagliflozin AUCss in females was estimated to be about 22% higher than in males.
Croatian: Procijenjeno je da je srednja vrijednost AUCss dapagliflozina u žena približno 22% veća nego u muškaraca.
English: At the usual metformin doses and dosing schedules, steady-state plasma concentrations are reached within 24-48 hours and are generally less than 1 μg/mL.
Croatian: Pri uobičajenim dozama i režimima primjene metformina koncentracije u stanju dinamičke ravnoteže u plazmi postižu se unutar 24-48 sati i obično su niže od 1 µg/ml.
English: • Lactic acidosis, seen very rarely (may affect up to 1 in 10,000 people) Xigduo may cause a very rare, but very serious side effect called lactic acidosis (see section “Warnings and precautions”).
Croatian: • Laktacidoza, vrlo rijetka (može se javiti u manje od 1 na 10 000 osoba), ali vrlo ozbiljna nuspojava koja se naziva laktacidoza (vidjeti dio „Upozorenja i mjere opreza“).
English: • if you are using certain medicines for the treatment of high blood pressure (ACE inhibitors and angiotensin II receptor antagonists).
Croatian: • određene lijekove za liječenje povišenog krvnog tlaka (ACE inhibitori i antagonisti receptora angiotenzina II)
English: The absolute oral bioavailability of dapagliflozin following the administration of a 10 mg dose is 78%.
Croatian: Apsolutna bioraspoloživost dapagliflozina nakon peroralne primjene doze od 10 mg iznosi 78%.
English: Because of how this medicine works, your urine will test positive for sugar while you are on this medicine.
Croatian: Zbog načina na koji djeluje ovaj lijek, nalazi pretraga na šećer u mokraći bit će pozitivni dok uzimate ovaj lijek.
English: Metformin passes into human milk in small amounts.
Croatian: Metformin se izlučuje u majčino mlijeko u malim količinama.
English: Pharmacotherapeutic group: Drugs used in diabetes, Combinations of oral blood glucose-lowering drugs, ATC code: A10BD15
Croatian: Farmakoterapijska skupina: Lijekovi za liječenje šećerne bolesti, Kombinacije oralnih antihiperglikemika, ATK oznaka: A10BD15
English: This medicine contains two different substances called dapagliflozin and metformin.
Croatian: Ovaj lijek sadrži dvije različite djelatne tvari koje se zovu dapagliflozin i metformin.
English: Therefore, this medicinal product is not expected to alter the metabolic clearance of coadministered medicinal products that are metabolised by these enzymes.
Croatian: Stoga se ne očekuje da bi ovaj lijek mogao izmijeniti metabolički klirens istodobno primijenjenih lijekova koje navedeni enzimi metaboliziraju.
English: If any of the above applies to you (or you are not sure), talk to your doctor, pharmacist or nurse before taking this medicine.
Croatian: Ako se nešto od gore navedenog odnosi na Vas (ili niste sigurni), obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego uzmete ovaj lijek.
English: Diagnostic laboratory findings are decreased blood pH (< 7.35), increased plasma lactate levels above 5 mmol/L, and an increased anion gap and lactate/pyruvate ratio.
Croatian: Dijagnostički laboratorijski nalazi su sniženi pH krvi (<7,35), povišene razine laktata u plazmi (>5 mmol/l) i povećan anionski procijep i omjer laktata/piruvata.
English: Dapagliflozin Effect on Cardiovascular Events (DECLARE) was an international, multicentre, randomised, double-blind, placebo-controlled clinical study conducted to determine the effect of dapagliflozin compared with placebo on cardiovascular outcomes when added to current background therapy.
Croatian: Ispitivanje DECLARE (Dapagliflozin Effect on Cardiovascular Events) bilo je međunarodno, multicentrično, randomizirano, dvostruko slijepo, placebom kontrolirano kliničko ispitivanje provedeno kako bi se utvrdio učinak dapagliflozina u usporedbi s placebom na kardiovaskularne ishode kada se primjenjuju kao dodatak trenutnoj osnovnoj terapiji.
English: The same recommendations for renal function apply to elderly patients as to all patients (see sections 4.2, 4.4, 4.8 and 5.1).
Croatian: U slučaju oštećenja bubrežne funkcije, za starije osobe vrijede iste preporuke kao i za sve ostale bolesnike (vidjeti dijelove 4.2, 4.4, 4.8 i 5.1).
English: • in combination with other medicinal products for the treatment of diabetes in patients insufficiently controlled with metformin and these medicinal products
Croatian: • u kombinaciji s drugim lijekovima za liječenje šećerne bolesti u bolesnika u kojih glikemija nije dovoljno dobro regulirana metforminom i tim lijekovima
English: Studies in rats treated with dapagliflozin have shown toxicity to the developing kidney in the time period corresponding to the second and third trimesters of human pregnancy (see section 5.3).
Croatian: Istraživanja na štakorima liječenima dapagliflozinom ukazala su na toksičnost za bubrege u razvoju u razdoblju koje odgovara drugom i trećem tromjesečju ljudske trudnoće (vidjeti dio 5.3).
English: Monitoring of renal function is necessary to aid in prevention of metformin-associated lactic acidosis, particularly in elderly patients (see sections 4.3 and 4.4).
Croatian: Potrebno je kontrolirati bubrežnu funkciju radi sprječavanja laktacidoze povezane s metforminom, osobito u starijih osoba (vidjeti dijelove 4.3 i 4.4).
English: Each tablet contains a fixed dose of dapagliflozin and metformin (see section 2).
Croatian: Svaka tableta sadrži fiksnu dozu dapagliflozina i metformina (vidjeti dio 2).
English: Posology Adults with normal renal function (glomerular filtration rate [GFR] ≥ 90 mL/min)
Croatian: Doziranje Odrasli s normalnom funkcijom bubrega (brzina glomerularne filtracije [GFR] ≥ 90 ml/min)
English: Your doctor may want to lower the dose of these other medicines, to prevent you from getting blood sugar levels that are too low (hypoglycaemia).
Croatian: Vaš će liječnik možda htjeti smanjiti dozu tih drugih lijekova kako bi spriječio prenisku razinu šećera u krvi (hipoglikemiju).
English: • if you have problems with your liver.
Croatian: • ako imate tegoba s jetrom
English: Maximum dapagliflozin plasma concentrations (Cmax) were usually attained within 2 hours after administration in the fasted state.
Croatian: Maksimalne koncentracije dapagliflozina u plazmi (Cmax) su obično bile dosegnute unutar 2 sata nakon primjene natašte.
English: 60x1 film-coated tablets in perforated unit dose blisters.
Croatian: 60x1 filmom obložena tableta u perforiranim blisterima djeljivima na jedinične doze.
English: These are medicines taken by mouth for diabetes.
Croatian: To su lijekovi za liječenje šećerne bolesti koji se uzimaju kroz usta.
English: In in vitro studies, dapagliflozin neither inhibited cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A4, nor induced CYP1A2, CYP2B6 or CYP3A4.
Croatian: U ispitivanjima in vitro dapagliflozin nije inhibirao izoenzime citokroma P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A4 niti je inducirao izoenzime CYP1A2,
English: Stop taking Xigduo and contact a doctor or the nearest hospital immediately if you experience some of the symptoms of lactic acidosis, as this condition may lead to coma.
Croatian: Prestanite uzimati Xigduo i odmah se obratite liječniku ili otiđite u najbližu bolnicu ako osjetite neke od simptoma laktacidoze, jer to stanje može dovesti do kome.
English: These findings were associated with dose-related increases in kidney weight and macroscopic kidney enlargement observed at all doses.
Croatian: Ti nalazi su povezani s o dozi ovisnom porastu težine bubrega i makroskopskim povećanjem bubrega koji su primijećeni kod svih doza.
English: They have “5/1000” on one side and “1069” on the other side.
Croatian: Na jednoj strani imaju oznaku „5/1000“, a na drugoj „1069“.
English: Xigduo with alcohol
Croatian: Xigduo s alkoholom
English: At baseline, 10.0% of patients had a history of heart failure.
Croatian: Na početku ispitivanja 10,0% bolesnika imalo je zatajenje srca u anamnezi.
English: In controlled clinical trials, maximum metformin plasma levels (Cmax) did not exceed 5 μg/mL, even at maximum doses.
Croatian: U kontroliranim kliničkim ispitivanjima vršne vrijednosti metformina u plazmi (Cmax) nisu čak ni pri najvišim dozama prelazile vrijednost od 4 µg/ml.
English: The metabolism of dapagliflozin is primarily via glucuronide conjugation mediated by UDP-glucuronosyltransferase 1A9 (UGT1A9).
Croatian: Metabolizam dapagliflozina prvenstveno se odvija putem glukuronidne konjugacije u kojoj posreduje UDP-glukuronoziltransferaza 1A9 (UGT1A9).
English: PARTICULARS TO APPEAR ON THE INTERMEDIATE PACKAGING
Croatian: PODACI KOJI SE MORAJU NALAZITI NA UNUTARNJEM PAKIRANJU
English: Polyuria includes the preferred terms: pollakiuria, polyuria, urine output increased.
Croatian: Poliurija uključuje preporučene pojmove: polakizurija, poliurija, pojačano mokrenje.
English: In rats, dapagliflozin was neither embryolethal nor teratogenic at exposures up to 1,441 times the maximum recommended human dose.
Croatian: U štakora dapagliflozin nije bio ni embrioletalan ni teratogen pri izloženosti do 1441 puta većoj od one kod maksimalne preporučene doze u ljudi.
English: How to take Xigduo
Croatian: Kako uzimati Xigduo
English: Dapagliflozin is approximately 91% protein bound.
Croatian: Otprilike 91% dapagliflozina veže se za proteine.
English: No major events of hypoglycaemia were reported.
Croatian: Nisu prijavljeni teški slučajevi hipoglikemije.
English: Because metformin is eliminated in part by the kidney, and because elderly patients are more likely to have decreased renal function, this medicinal product should be used with caution as age increases.
Croatian: Budući da se metformin dijelom eliminira putem bubrega, a obzirom da u starijih osoba postoji veća vjerojatnost smanjene bubrežne funkcije, ovaj lijek se mora primjenjivati uz oprez što je bolesnik stariji.
English: • changes in the amount of cholesterol or fats in your blood (shown in tests)
Croatian: • promjene količine kolesterola ili masti u krvi (vidljivo iz nalaza pretraga)
English: Biotransformation Metformin is excreted unchanged in the urine.
Croatian: Biotransformacija Metformin se izlučuje mokraćom u neizmijenjenu obliku.
English: If this happens to you, you may need immediate hospital treatment, as lactic acidosis may lead to coma.
Croatian: Ako se ovo dogodi Vama, možda ćete trebati odmah zatražiti liječenje u bolnici budući da laktacidoza može dovesti do kome.
English: These may be medicine(s) by mouth or given by injection, such as insulin or a GLP-1 receptor agonist.
Croatian: To mogu biti neki lijekovi koji se uzimaju kroz usta ili lijekovi koji se primjenjuju injekcijom, kao što je inzulin ili agonist GLP-1 receptora.
English: • if you have uncontrolled diabetes, with, for example severe hyperglycaemia (high blood glucose), nausea, vomiting, diarrhoea, rapid weight loss, lactic acidosis (see “Risk of lactic acidosis” below) or ketoacidosis.
Croatian: • ako imate nekontroliranu šećernu bolest uz, primjerice, tešku hiperglikemiju (visoka razina glukoze u krvi), mučninu, povraćanje, proljev, brz gubitak tjelesne težine, laktacidozu (vidjeti „Rizik od laktacidoze“ niže) ili ketoacidozu.
English: C]-dapagliflozin dose, 96% was recovered, 75% in urine and 21% in faeces.
Croatian: C] dapagliflozina u dozi od 50 mg pronađeno je 96% lijeka, od čega 75% u mokraći i 21% u fecesu.
English: In an analysis of 5 placebo-controlled dapagliflozin add-on to metformin studies, the safety results were similar to that of the pre-specified pooled analysis of 13 placebo-controlled dapagliflozin studies (see Dapagliflozin, Summary of the safety profile below).
Croatian: U analizi 5 placebom kontroliranih ispitivanja dapagliflozina kao dodatka metforminu, rezultati sigurnosti bili su slični onima iz unaprijed određene objedinjene analize 13 placebom kontroliranih ispitivanja dapagliflozina (vidjeti Dapagliflozin, Sažetak sigurnosnog profila u nastavku).
English: Your doctor may prescribe this medicine together with other medicine(s) to lower the amount of sugar in your blood.
Croatian: Liječnik može propisati ovaj lijek s drugim lijekovima za snižavanje razine šećera u krvi.