FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients with hepatic impairment and renal impairment: dose adjustment is recommended (see Patients with moderate to severe renal impairment above).
Danish: Patienter med nedsat leverfunktion og nedsat nyrefunktion: Dosisjustering anbefales (se Patienter med moderat til alvorlig nedsat nyrefunktion ovenfor).
English: The use of the product is not recommended in children aged less than 2 years.
Danish: Dette produkt bør ikke anvendes til børn under 2 år.
English: Double blind controlled clinical or pharmacoclinical trials comparing cetirizine to placebo or other antihistamines at the recommended dosage (10 mg daily for cetirizine), of which quantified safety data are available, included more than 3200 subjects exposed to cetirizine.
Danish: Dobbeltblinde kontrollerede kliniske forsøg eller kliniske farmakologiske forsøg, som sammenlignede cetirizin med placebo eller andre antihistaminer ved den anbefalede dosis (10 mg daglig for cetirizin), med tilgængelige kvantitative sikkerhedsdata, omfattede mere end 3200 personer, som fik cetirizin.
English: In a placebo-controlled study, cetirizine given at the high daily dose of 60 mg for seven days did not cause statistically significant prolongation of QT interval.
Danish: I en placebokontrolleret undersøgelse, hvor cetirizin blev givet i en høj daglig dosis på 60 mg i 7 dage, sås der ikke signifikant forlængelse af QT-intervallet.
English: To use this dosing table, an estimate of the patient's creatinine clearance (CLcr) in ml/min is needed.
Danish: For at anvende doseringstabellen, er det nødvendigt, at beregne patientens kreatinin clearance (CLcr) i ml/min.
English: The MAH was also asked to justify the dosing in paediatric patients suffering from renal impairment and the dosing by weight in the 2-5 year age group and dosing by age groups 2-5, 6-11 and 12-18 as well as dosing for children less than 2 years old.
Danish: Indehaveren af markedsføringstilladelsen blev også bedt om at begrunde doseringen til pædiatriske patienter med nedsat nyrefunktion og doseringen efter vægt i aldersgruppen 2-5 år og doseringen efter aldersgrupperne 2-5, 6-11 og 12-18 samt dosering til børn, som er under 2 år gamle.
English: The CHMP asked the MAH to revise the wording, restrict and define the indication in rhinoconjunctivitis rather than in conjunctivitis alone and discuss seasonal conjunctivitis, itching and allergic pruritis, severe skin reactions induced by mosquito and atopic dermatitis, as they should be considered as separate entities requiring more supportive data.
Danish: CHMP bad indehaveren af markedsføringstilladelsen om at revidere formuleringen, begrænse og definere indikationen for rhinoconjunctivitis, frem for conjunctivitis alene, og diskutere sæsonbetinget conjunctivitis, kløe og allergisk pruritus, svære hudreaktioner induceret af myg og atopisk dermatit, da de skal betragtes som separate enheder, som kræver mere underbyggende data.
English: In a six-week, placebo-controlled study of 186 patients with allergic rhinitis and concomitant mild to moderate asthma, cetirizine 10 mg once daily improved rhinitis symptoms and did not alter pulmonary function.
Danish: I en 6-ugers placebokontrolleret undersøgelse med 186 patienter med både allergisk rhinitis og mild til moderat astma, forbedrede cetirizin 10 mg én gang daglig rhinitissymptomerne og påvirkede ikke lungefunktionen.
English: Do not use Zyrtec after the expiry date which is stated on the box and blister.
Danish: Brug ikke Zyrtec efter den udløbsdato, der står på æsken og blisteren.
English: The duration of treatment depends on the type, duration and course of your complaints and is determined by your doctor.
Danish: Behandlingsvarigheden afhænger af type, varighed og forløb af Deres symptomer.
English: Patients with moderate renal impairment had a 3-fold increase in half-life and 70 % decrease in clearance compared to healthy volunteers.
Danish: Patienter med moderat nedsat nyrefunktion havde 3 gange så lang halveringstid og et fald i clearance på 70 % sammenlignet med raske frivillige.
English: UCB Nordic A/S Arne Jacobsens Allé 15 DK-2300 Kobenhavn S Denmark
Danish: UCB Nordic A/S Arne Jacobsens Allé 15 DK-2300 København S Danmark
English: Objective measurements of driving ability, sleep latency and assembly line performance have not demonstrated any clinically relevant effects at the recommended dose of 10 mg.
Danish: Objektive målinger af køreevne, søvnlatens og samlebåndsarbejde har ikke vist påvirkninger af klinisk relevans ved anvendelse af den anbefalede dosis på 10 mg.
English: Caution should be exercised when prescribing to pregnant or breast feeding women because cetirizine passes into breast milk.
Danish: Der bør udvises forsigtighed ved ordination til gravide eller ammende kvinder, fordi cetirizin udskilles i modermælken.
English: ZYRTEC COMPRIMIDOS RECUBIERTOS CON PELICULA
Danish: ZYRTEC COMPRIMIDOS RECUBIERTOS CON
English: Although cetirizine is a selective antagonist of peripheral H1-receptors and is relatively free of anticholinergic activity, isolated cases of micturition difficulty, eye accommodation disorders and dry mouth have been reported.
Danish: Selvom cetirizin er en selektiv perifer H1-receptor antagonist og stort set ikke har antikolinerg aktivitet, er der rapporteret isolerede tilfælde af vandladningsbesvær, akkommodationsforstyrrelse og mundtørhed.
English: UCB GmbH Huttenstraße 205 D-50170 Kerpen Germany
Danish: UCB GmbH Huttenstraße 205 D-50170 Kerpen Tyskland
English: Oral solution Bottle of 60 ml Bottle of 75 ml Bottle of 100 ml Bottle of 125 ml Bottle of 150 ml Bottle of 200 ml
Danish: Oral opløsning Flaske á 60 ml Flaske á 75 ml Flaske á 100 ml Flaske á 125 ml Flaske á 150 ml Flaske á 200 ml
English: A 5ml Dosing spoon with a line at 2.5 ml is provided with the bottle.
Danish: Det er vedlagt en 5 ml doseringsske med en streg ved 2,5 ml sammen med flasken.
English: Please follow these instructions, otherwise Zyrtec may not be fully effective.
Danish: Følg venligst disse anvisninger, ellers kan virkningen af Zyrtec nedsættes.
English: From this pooling, the following adverse events were reported for cetirizine 10 mg in the placebocontrolled trials at rates of 1.0 % or greater:
Danish: Ud fra denne pooling, blev der i placebokontrollerede forsøg rapporteret om følgende bivirkninger for cetirizin 10 mg med hyppigheder på 1,0 % eller derover:
English: Uncommon: agitation
Danish: Ikke almindelig: agitation
English: The MAH stated that the clinical benefit/risk ratio of cetirizine has not been specifically evaluated in patients with renal impairment and that the dose is therefore based on pharmacokinetic calculations only.
Danish: Indehaveren af markedsføringstilladelsen meddelte, at cetirizins kliniske risk/benefit-forhold ikke er blevet specifikt vurderet hos patienter med nedsat nyrefunktion, og at dosen derfor udelukkende er baseret på farmakokinetiske beregninger.
English: Actually, neither pharmacodynamic nor significant pharmacokinetic interaction was reported in drug-drug interactions studies performed, notably with pseudoephedrine or theophylline (400 mg/day).
Danish: Faktisk blev der ikke rapporteret hverken farmakodynamiske eller signifikante farmakokinetiske interaktioner i lægemiddel-lægemiddel-interaktionsundersøgelser, især med pseudoephedrin eller theophyllin (400 mg daglig).
English: The MAH agreed with the CHMP recomendations but considered that the sentence on food interaction should be retained as it is independent from the liver enzymes interactions.
Danish: Indehaveren af markedsføringstilladelsen var enig i anbefalingerne fra CHMP, men mente, at sætningen om interaktion med fødeindtagelse skulle bevares, da dette er uafhængigt af leverenzyminteraktionerne.
English: In these sensitive patients, concurrent use with alcohol or other CNS depressants may cause additional reductions in alertness and impairment of performance.
Danish: Hos følsomme patienter kan samtidig anvendelse af alkohol eller andre CNS-depressiva medføre yderligere reduktion af opmærksomhed og svække præstationsevnen.
English: Hypersensitivity to the active substance, to any of the excipients, to hydroxyzine or to any piperazine derivatives.
Danish: Overfølsomhed over for det aktive stof, over for et eller flere af hjælpestofferne eller over for hydroxyzin eller piperazin derivater.
English: The MAH argued that the paediatric use of cetirizine in the same indications as in adults is justified, as no pathophysiological reason was identified for not using antihistamines in the paediatric population, provided the dose is adequately adapted to different body weight, age and clearance of the drug.
Danish: Indehaveren af markedsføringstilladelsen anførte, at pædiatrisk brug af cetirizin ved de samme indikationer som til voksne er berettiget, da der ikke er påvist nogen patofysiologisk årsag til ikke at anvende antihistaminer til den pædiatriske population under forudsætning af, at dosis er tilstrækkeligt tilpasset forskellen i legemsvægt, alder og clearance af lægemidlet.
English: Greece: Ziptek
Danish: Grækenland: Ziptek
English: Elderly subjects: data do not suggest that the dose needs to be reduced in elderly subjects provided that the renal function is normal.
Danish: Ældre patienter: Data tyder ikke på at dosis behøver justeres til ældre patienter, forudsat at nyrefunktionen er normal.
English: - 10 ml Zyrtec oral solution (=2 measuring spoons) contain: 3.15 g glucose equivalents (sorbitol).
Danish: - 10 ml Zyrtec oral opløsning (=2 måleskeer) indeholder: Sorbitol (svarende til 3,15 g glucose).
English: Regarding dosage under the age of 2, the MAH justified the dosing based on PK data.
Danish: Vedrørende dosering under 2 års-alderen begrundede indehaveren af markedsføringstilladelsen doseringen baseret på farmakokinetiske data.
English: ANNEX II SCIENTIFIC CONCLUSIONS AND GROUNDS FOR THE SUMMARIES OF PRODUCT CHARACTERISTICS, LABELLING AND PACKAGE LEAFLET PRESENTED BY THE EMEA
Danish: BILAG II FAGLIGE KONKLUSIONER OG BEGRUNDELSER FOR ÆNDRING AF PRODUKTRESUMÉER, ETIKETTERING OG INDLÆGSSEDDEL FREMLAGT AF EMEA
English: The drug is authorised for the symptomatic treatment of seasonal allergic rhinitis, perennial allergic rhinitis, and various types of pruritus and dermatological conditions from allergic origin, in particular chronic idiopathic urticaria.
Danish: Lægemidlet er godkendt til symptomatisk behandling af sæsonbetinget allergisk rinit, vedvarende allergisk rinit og flere typer pruritus og dermatologiske lidelser af allergisk oprindelse, særligt kronisk idiopatisk urticaria.
English: Clinical studies have produced no evidence of impaired attention, alertness and driving capabilities after taking Zyrtec at the recommended dose.
Danish: Kliniske undersøgelser har ikke påvist nedsat opmærksomhed, årvågenhed eller køreevner efter brug af den anbefalede dosis af Zyrtec.
English: The MAH provided extensive testing data from the review of therapeutic trials and the corresponding clinical study reports in support of these indications and proposed the removal of the other indications such as atopic dermatitis, prevention of asthma, mosquito bites as the clinical evidences available to support these indications was considered insufficient.
Danish: Indehaveren af markedsføringstilladelsen fremlagde omfattende testdata fra gennemgangen af terapeutiske undersøgelser og de tilsvarende kliniske undersøgelsesrapporter, som underbygger disse indikationer, og foreslog at fjerne de andre indikationer, som atopisk dermatit, forebyggelse af astma samt myggestik, da den foreliggende kliniske dokumentation, som støtter disse indikationer, blev betragtet som utilstrækkelig.
English: Pack with a bottle of 10, 15, 20, or 30 ml solution.
Danish: Pakning med en flaske á 10, 15, 20 eller 30 ml opløsning.
English: The MAH also proposed harmonised Product Information texts for section 4.3 Contraindications reflecting the hypersensitivity to formulation constituents and addressing patients with severe renal impairment.
Danish: Indehaveren af markedsføringstilladelsen foreslog også harmoniserede tekster til produktinformationens afsnit 4.3 Kontraindikationer, som afspejler overfølsomhed over for formuleringens bestanddele og omfatter patienter med svært nedsat nyrefunktion.
English: Methyl parahydroxybenzoate and propyl parahydroxybenzoate may cause allergic reactions (possibly delayed).
Danish: Methylparahydroxybenzoat og propylparahydroxybenzoat kan give allergiske reaktioner (muligvis forsinket).
English: Adverse drug reactions (WHO-ART)
Danish: Bivirkninger (WHO-ART)
English: Instances of abnormal hepatic function with elevated hepatic enzymes accompanied by elevated bilirubin have been reported.
Danish: Der er rapporteret tilfælde af unormal leverfunktion med forhøjede leverenzymer ledsaget af forhøjet bilirubin.
English: UCB PHARMA LIMITED 208 Bath Road SLOUGH
Danish: Storbritannien UCB PHARMA LIMITED 208 Bath Road
English: Spain: Alerlisin, Virlix, Reactine, Zyrtec comprimidos recubiertos con pelicula, Alerrid 10 mg comprimidos recubiertos con pelicula
Danish: Spainienn: Alerlisin, Virlix, Reactine, Zyrtec comprimidos recubiertos con pelicula, Alerrid 10 mg comprimidos recubiertos con pelicula
English: The MAH was also asked to provide data in support of the recommended dosing in patients with renal impairment and provide justifications for the benefit/risk ratio of halving the dose.
Danish: Indehaveren af markedsføringstilladelsen blev også bedt om at fremlægge data til begrundelse for den anbefalede dosis hos patienter med nedsat nyrefunktion samt fremlægge begrundelse for risk/benefitforholdet ved en dosishalvering.
English: End-stage renal diseasePatients undergoing dialysis
Danish: Terminalstadiet af nyresygdomPatienter i dialyse
English: Rare: urticaria
Danish: Sjælden: urticaria
English: Patients with moderate to severe renal impairment: there are no data to document the efficacy/safety ratio in patients with renal impairment.
Danish: Patienter med moderat til alvorlig nedsat nyrefunktion: Der foreligger ikke data som dokumenterer effekt/sikkerhedsforholdet hos patienter med nedsat nyrefunktion.
English: WHAT Zyrtec IS AND WHAT IT IS USED FOR
Danish: ZYRTEC S VIRKNING OG HVAD DE SKAL BRUGE DET TIL
English: Regarding the dosing by weight, the MAH responded that systemic exposure to cetirizine is not only a function of body weight but also of renal clearance of the drug, with studies demonstrating that clearance is more important when age is low.
Danish: Vedrørende dosering efter vægt svarede indehaveren af markedsføringstilladelsen, at systemisk eksponering for cetirizin ikke kun er en funktion af legemsvægten, men også af den renale clearance af lægemidlet, hvor undersøgelser viser, at clearance er vigtigst ved lav alder.
English: Adverse event (WHO-ART)
Danish: Bivirkning (WHO-ART)
English: White, oblong, film-coated tablet, with breakline and Y-Y logo
Danish: Hvid, aflang, filmovertrukket tablet med delekærv og mærket Y-Y
English: Important information about some of the ingredients of Zyrtec
Danish: Vigtig information om nogle af de øvrige indholdsstoffer i Zyrtec.
English: Very rare: angioneurotic oedema, fixed drug eruption
Danish: Meget sjælden: angioneurotisk ødem, fikseret lægemiddel udslæt
English: Rare: hypersensitivity Very rare: anaphylactic shock
Danish: Sjælden: overfølsomhed Meget sjælden: anafylaktisk shock
English: For children with renal impairment, the clinical effects or the pharmacokinetics of cetirizine have never been tested but the MAH agreed that the current wording is not entirely correct since the age of the patient is important as it determines its clearance.
Danish: Den kliniske effekt af cetirizins farmakokinetik er aldrig blevet undersøgt hos børn med nedsat nyrefunktion, men indehaveren af markedsføringstilladelsen var enig i, at den aktuelle formulering ikke er helt korrekt, da patientens alder er vigtig, fordi den er afgørende for clearance.
English: - Immune system disorders: rare: allergic reactions, some severe (very rare)
Danish: Immunsystemet: Sjælden: overfølsomhedsreaktioner, nogle alvorlige (meget sjælden)
English: For these less frequently reported undesirable effects, the estimated frequencies (uncommon: ≥1/1,000 to 1/100, rare: ≥1/10,000 to 1/1,000, very rare: 1/10,000) are made based on post-marketing experience.
Danish: For disse mindre hyppigt rapporterede bivirkninger er de beregnede frekvenser (ikke almindelig: ≥1/1.000 til < 1/100, sjælden: ≥1/10.000 til < 1/1.000, meget sjælden: < 1/10.000) vurderet efter markedsføring.
English: PHARMACEUTICAL FORM Oral drops, solution Clear and colorless liquid
Danish: LÆGEMIDDELFORM Oral opløsning Klar og farveløs væske
English: Children between 6 and 12 years old:
Danish: Børn mellem 6 og 12 år:
English: You should not take Zyrtec 1 mg/ml oral solution: - if you have rare hereditary problems of fructose intolerance
Danish: De må ikke tage Zyrtec 1 mg/ml oral opløsning: - hvis De har sjælden arvelig fructoseintolerans
English: Cetirizine dihydrochloride
Danish: Cetirizindihydrochlorid
English: No interactions suceptible to have a noticeable impact have been observed between alcohol (at the blood level of 0.5 per mille corresponding to one glass of wine) and cetirizine used at the normal doses.
Danish: Der er ikke set mærkbar gensidig påvirkning mellem alkohol (ved blodalkoholniveau på 0,5 promille svarende til et glas vin) og cetirizin anvendt i normale doser.
English: McNeil Products Limited Walton Oaks, Dorking Road, Walton on the Hill, Surrey KT20 7NS UK
Danish: Storbritannien McNeil Products Limited Walton Oaks, Dorking Road, Walton on the Hill, Surrey KT20 7NS Storbritannien
English: Amber glass bottle (type III) with 10, 15, 20, or 30 ml solution, fitted with a dropper insert in white low density polyethylene and closed with a white polypropylene child-resistant closure.
Danish: Gyldenbrun glasflaske (type III) med 10, 15, 20 eller 30 ml opløsning med dråbeindsats af lavdensitets polyethylen, lukket med en hvid børnesikret lukkeanordning af polypropylen.
English: Body as a whole - general disorders Fatigue
Danish: Hele kroppen - almene symptomer Træthed
English: Ltd (CY) 8 Ayiou Nicolaou Street P.O.
Danish: Ltd (CY) 8 Ayiou Nicolaou Street P.O. Box 22679
English: Adverse events reported after an intake of at least 5 times the recommended daily dose are: confusion, diarrhoea, dizziness, fatigue, headache, malaise, mydriasis, pruritus, restlessness, sedation, somnolence, stupor, tachycardia, tremor, and urinary retention.
Danish: Bivirkninger, som er rapporteret efter indtagelse af mindst 5 gange den anbefalede daglige dosis, er: konfusion, diarré, træthed, hovedpine, utilpashed, mydriasis, kløe, rastløshed, sedation, døsighed, stupor, takykardi, tremor og urinretention.
English: Film-coated tablets 1 tablet
Danish: Filmovertrukne tabletter 1 tablet
English: Boxes of 1, 4, 5, 7, 10, 14, 15, 20, 21, 30, 40, 45, 50, 60, 90, or 100 tablets.
Danish: Karton á 1, 4, 5, 7, 10, 14, 15, 20, 21, 30, 40, 45, 50, 60, 90 eller 100 tabletter.
English: In addition to its anti-H1 effect, cetirizine was shown to display anti-allergic activities: at a dose of 10 mg once or twice daily, it inhibits the late phase recruitment of eosinophils, in the skin and conjunctiva of atopic subjects submitted to allergen challenge.
Danish: Ud over H1-receptorblokerende virkning har cetirizin vist antiallergiske egenskaber: ved en dosis på 10 mg én eller to gange daglig, hæmmer det migrationen af eosinofile celler i hud og conjunctiva hos atopiske personer som bliver udsat for allergen provokation.
English: PHARMACOLOGICAL PROPERTIES 5.1 Pharmacodynamic properties Pharmacotherapeutic group: Piperazine derivatives, ATC code: R06A E07
Danish: FARMAKOLOGISKE EGENSKABER 5.1 Farmakodynamiske egenskaber Farmakoterapeutisk klassifikation: Piperazinderivater, ATC-kode: R 06 AE 07
English: Adults and adolescents above 12 years old:
Danish: Voksne og unge over 12 år:
English: Pharmacotherapeutic group: Piperazine derivatives, ATC code: R06A E07
Danish: Farmakoterapeutisk klassifikation: Piperazinderivater, ATC-kode: R 06 AE 07
English: Adverse drug reactions at rates of 1 % or greater in children aged from 6 months to 12 years, included in placebo-controlled clinical or pharmacoclinical trials are:
Danish: Bivirkninger, hos børn fra 6 måneder til 12 år som deltog i placebokontrollerede kliniske forsøg eller kliniske farmakologiske forsøg, med en hyppighed på mindst 1 % er:
English: Amber glass bottle (type III) of 60, 75, 100, 125, 150, or 200 ml, closed with a white polypropylene child-resistant closure.
Danish: Gyldenbrun glasflaske (type III) á 60, 75, 100, 125, 150 eller 200 ml, lukket med en hvid børnesikret lukkeanordning af polypropylen.
English: Excipients: - one ml of solution contains 1.35 mg methylparahydroxybenzoate
Danish: Hjælpestoffer: - en ml opløsning indeholder 1,35 mg methylparahydroxybenzoat
English: Due to the divergent national decisions taken by Member States concerning the authorisation of Zyrtec, a number of divergences exist in the product information and a referral was therefore triggered by the European Commission Article 30 of Directive 2001/83/EC as amended in order to harmonise the divergent Product Information texts across the EU.
Danish: Derfor indbragte Europa-Kommissionen en sag i henhold til artikel 30 i direktiv 2001/83/EF, med senere ændringer, med henblik på at harmonisere de afvigende tekster i produktinformationerne i hele EU.
English: McNeil Sweden AB,
Danish: McNeil Sweden AB, Sollentuna Sverige
English: Quinta da Fonte 2770-229 PACO DE ARCOS
Danish: 2770-229 PACO DE ARCOS
English: Slovenia: Zyrtec10 mg filmsko oblozene tablete
Danish: Slovenien: Zyrtec10 mg filmsko oblozene tablete
English: Renally impaired patients: The pharmacokinetics of the drug were similar in patients with mild impairment (creatinine clearance higher than 40 ml/min) and healthy volunteers.
Danish: Patienter med nedsat nyrefunktion: Lægemidlets farmakokinetik var ens hos patienter med let nedsat nyrefunktion (kreatininclearance større end 40 ml/min) og hos raske frivillige.
English: Psychiatric disorders Somnolence
Danish: Psykiske forstyrrelser Somnolens
English: How to store Zyrtec Further information
Danish: Sådan opbevarer De Zyrtec Yderligere oplysninger
English: In adults and paediatric patients 6 year and above:
Danish: Voksne og pædiatriske patienter fra 6 år:
English: oral solution
Danish: Oral opløsning
English: In adults, children, infants and toddlers 2 year and above:
Danish: Hos voksne, børn, spædbørn og små børn, som er fyldt 2 år:
English: Hepatically impaired patients: Patients with chronic liver diseases (hepatocellular, cholestatic, and biliary cirrhosis) given 10 or 20 mg of cetirizine as a single dose had a 50 % increase in half-life along with a 40 % decrease in clearance compared to healthy subjects.
Danish: Patienter med nedsat leverfunktion: Patienter med kronisk leversygdom (hepatocellulær, kolestatisk og biliær cirrhose) som fik en enkeltdosis cetirizin på 10 eller 20 mg, havde en 50 % stigning i halveringstiden samt et fald på 40 % i clearance sammenlignet med raske personer.
English: Germany: Zyrtec P tropfen, Zyrtec tropfen Greece: Ziptek
Danish: Tyskland: Zyrtec P tropfen, Zyrtec tropfen Grækenland: Ziptek
English: Austria: Zyrtec 10 mg -Filmtabletten
Danish: Østrig: Zyrtec 10 mg - Filmtabletten
English: The sentence will therefore be adapted to: “In paediatric patients suffering from renal impairment, the dose will have to be adjusted on an individual basis taking into account the renal clearance of the patient, his age, and his body weight”
Danish: Sætningen skal derfor ændres til: “Hos pædiatriske patienter med nedsat nyrefunktion skal dosis justeres på individuel basis på grundlag af patientens renale clearance, alder og legemsvægt.”
English: Cetirizine dihydrochloride is the active ingredient of Zyrtec.
Danish: Cetirizindihydrochlorid er det aktive stof i Zyrtec.
English: - You must contact a doctor if your symptoms worsen or do not improve after 3 days.
Danish: - Kontakt lægen, hvis de får det værre, eller hvis De ikke får det bedre.