FrancophonIA/ELRC3.0 huggingface dataset:
English: Adalimumab treated patients demonstrated statistically significant improvement in physical function as assessed by HAQ and Short Form Health Survey (SF 36) compared to placebo at week 24.
Croatian: Nakon 24 tjedna u bolesnika liječenih adalimumabom je u odnosu na bolesnike liječene placebom zabilježeno statistički značajno poboljšanje fizičke funkcije, koja se ocjenjivala uz pomoć upitnika HAQ i kratke zdravstvene ankete SF 36.
English: In CD study I, 299 TNF-antagonist naive patients were randomised to one of four treatment groups; placebo at weeks 0 and 2, 160 mg adalimumab at week 0 and 80 mg at week 2, 80 mg at week 0 and 40 mg at week 2, and 40 mg at week 0 and 20 mg at week 2.
Croatian: U ispitivanju CD I, 299 bolesnika koji nikad nisu primali terapiju antagonistima TNF-a randomizirani su u jednu od 4 terapijske skupine: placebo u nultom tjednu i nakon 2 tjedna, adalimumab 160 mg u nultom tjednu i 80 mg nakon 2 tjedna, adalimumab 80 mg u nultom tjednu i 40 mg nakon 2 tjedna, adalimumab 40 mg u nultom tjednu i 20 mg nakon 2 tjedna.
English: The blinded period was followed by an open−label period during which patients received adalimumab 40 mg every other week subcutaneously for up to an additional 28 weeks.
Croatian: Nakon slijepog dijela ispitivanja slijedio je otvoreni dio ispitivanja u kojem su bolesnici svaki drugi tjedan dobivali 40 mg adalimumaba supkutano kroz dodatnih 28 tjedana.
English: Initial dose of 80 mg (as two 40 mg injections in one day), followed by 40 mg two weeks later.
Croatian: Početna doza 80 mg (u obliku dvije injekcije od 40 mg u jednom danu), nakon čega poslije dva tjedna slijedi doza od 40 mg.
English: Kromeya 40 mg/0.8 mL injection adalimumab
Croatian: Kromeya 40 mg/0,8 ml injekcija adalimumab s.c.
English: Response RA study I a**
Croatian: Ispitivanje RA I a**
English: • Store the pre-filled syringe in a refrigerator between 2°C to 8°C.
Croatian: • Čuvajte napunjenu brizgalicu u hladnjaku na temperaturi između 2°C i 8°C.
English: p-value
Croatian: P vrijednost
English: Adverse events of the haematologic system, including medically significant cytopenia (e.g. thrombocytopenia, leucopenia) have been reported with adalimumab.
Croatian: U bolesnika liječenih adalimumabom prijavljeni su štetni događaji u hematološkom sustavu, uključujući medicinski značajne citopenije (npr. trombocitopenija, leukopenija).
English: Nail psoriasis assessments included the Modified Nail Psoriasis Severity Index (mNAPSI), the Physician's Global Assessment of Fingernail Psoriasis (PGA-F) and the Nail Psoriasis Severity Index (NAPSI) (see Table 19).
Croatian: Modified Nail Psoriasis Severity Index, mNAPSI), liječnikovu opću procjenu psorijaze noktiju na rukama (engl.
English: In controlled Phase 3 trials of adalimumab in patients with rheumatoid arthritis and psoriatic arthritis with a control period duration ranging from 4 to 104 weeks, ALT elevations ≥ 3 x ULN occurred in 3.7% of adalimumab-treated patients and 1.6% of control-treated patients.
Croatian: U kontroliranim ispitivanjima faze III u kojima se adalimumab primjenjivao u bolesnika s reumatoidnim artritisom i psorijatičnim artritisom, s kontrolnim razdobljem koje je trajalo u rasponu od 4 do 104 tjedna, povišenje razine ALT-a ≥3 x GGN (gornja granica normalnog raspona) zabilježeno je u 3,7% bolesnika liječenih adalimumabom i 1,6% bolesnika iz kontrolne skupine.
English: Initial dose of 80 mg (as two 40 mg injections), followed by 40 mg every other week starting one week after the initial dose.
Croatian: Početna doza od 80 mg (u obliku dvije injekcije od 40 mg u jednom danu), nakon čega slijedi 40 mg svaki drugi tjedan počevši tjedan dana nakon početne doze.
English: If you do not respond well enough to these medicines, you will be given Kromeya to reduce the signs and symptoms of your Crohn's disease.
Croatian: Ako na njih ne reagirate dovoljno dobro, u svrhu smanjenja znakova i simptoma Crohnove bolesti bit će Vam propisan lijek Kromeya.
English: Clinical remission 12% 24% 36%*
Croatian: 12. tjedan 14% 58% 24. tjedan 15% 57%***
English: Adalimumab 40 mg eow N=814 n (%)
Croatian: Adalimumab 40 mg svaki drugi tjedan, N=814 n (%)
English: Tuberculosis, including reactivation and new onset of tuberculosis, has been reported in patients receiving adalimumab.
Croatian: Unatoč profilaksi tuberkuloze, zabilježeni su slučajevi reaktivacije tuberkuloze u bolesnika liječenih adalimumabom.
English: RA study III a**
Croatian: Ispitivanje RA III a**
English: A loading dose of 160 mg adalimumab on week 0 followed by 80 mg adalimumab on week 2 achieves serum adalimumab trough concentrations of approximately 12 µg/mL during the induction period.
Croatian: Primjenom udarne doze od 160 mg adalimumaba u nultom tjednu i zatim 80 mg u 2. tjednu postižu se najniže serumske koncentracije adalimumaba od približno 12 μg/ml tijekom razdoblja indukcije.
English: The decision to stop using Kromeya should be discussed with your child's doctor.
Croatian: Ako Vaše dijete prestane uzimati lijek Kromeya Odluku o prekidu primjene lijeka Kromeya potrebno je raspraviti s djetetovim liječnikom.
English: Figure L
Croatian: Slika L
English: Some patients who experience decrease in their response to Kromeya 40 mg every other week may benefit from an increase in dosage to 40 mg Kromeya every week or 80 mg every other week.
Croatian: U nekih bolesnika u kojih dođe do slabljenja odgovora na terapiju lijekom Kromeya u dozi od 40 mg svaki drugi tjedan možda će biti korisno povećati doziranje na 40 mg lijeka Kromeya svaki tjedan ili 80 mg svaki drugi tjedan.
English: Step 3 Check the Pre-filled Pen
Croatian: 3. korak Provjerite brizgalicu
English: At week 16, more patients randomised to adalimmab 0.8 mg/kg had positive efficacy responses (e.g. PASI 75) than those randomised to 0.4 mg/kg eow or MTX.
Croatian: U 16. tjednu, pozitivan odgovor s obzirom na djelotvornost (npr. PASI 75) postigao je veći broj bolesnika randomiziranih za liječenje adalimumabom u dozi od 0,8 mg/kg nego onih randomiziranih za primanje doze od 0,4 mg/kg svaki drugi tjedan ili za liječenje MTX-om.
English: Kromeya is indicated for treatment of moderately to severely active Crohn's disease, in adult patients who have not responded despite a full and adequate course of therapy with a corticosteroid and/or an immunosuppressant; or who are intolerant to or have medical contraindications for such therapies.
Croatian: Kromeya je indicirana za liječenje umjerenog do teškog oblika aktivne Crohnove bolesti u odraslih bolesnika u kojih unatoč prethodnom potpunom i odgovarajućem tijeku liječenja kortikosteroidima i/ili imunosupresivima nije postignut odgovor ili kod bolesnika koji ih ne podnose ili im je takva terapija kontraindicirana.
English: In adult patients with uveitis, a loading dose of 80 mg adalimumab on week 0 followed by 40 mg adalimumab every other week starting at week 1, resulted in mean steady-state concentrations of approximately 8 to 10 µg/mL.
Croatian: U odraslih bolesnika s uveitisom, udarna doza adalimumaba od 80 mg u nultom tjednu nakon čega slijedi 40 mg svaki drugi tjedan, počevši od 1. tjedna, dovela je do srednje vrijednosti koncentracija u stanju dinamičke ravnoteže od približno 8 - 10 µg/ml.
English: In the open-label extension for RA study III, most patients who were ACR responders maintained response when followed for up to 10 years.
Croatian: U većine je bolesnika postignuti ACR odgovor održan u otvorenom produžetku ispitivanja RA III kada su praćeni do 10 godina.
English: The recommended dose of Kromeya for adult patients with rheumatoid arthritis is 40 mg adalimumab administered every other week as a single dose via subcutaneous injection.
Croatian: U odraslih bolesnika s reumatoidnim artritisom preporučena doza adalimumaba iznosi 40 mg, a daje se kao jednokratna doza svaka dva tjedna supkutanom injekcijom.
English: Step 4 Prepare Needle
Croatian: 4. korak Pripremite iglu
English: Ankylosing spondylitis and axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, are inflammatory diseases of the spine.
Croatian: Ankilozantni spondilitis i aksijalni spondiloartritis bez radiološkog dokaza AS-a Ankilozantni spondilitis i aksijalni spondiloartritis bez radiološkog dokaza AS-a upalne su bolesti kralježnice.
English: The recommended dose of Kromeya for adult patients with uveitis is an initial dose of 80 mg, followed by 40 mg given every other week starting one week after the initial dose.
Croatian: Preporučena doza lijeka Kromeya u odraslih bolesnika s uveitisom je početna doza od 80 mg, nakon koje slijedi doza od 40 mg svaki drugi tjedan, počevši tjedan dana nakon početne doze.
English: Single use pre-filled pen (adalimumab) for subcutaneous injection 40mg
Croatian: Napunjena štrcaljka (adalimumab) za potkožnu primjenu, za jednokratnu primjenu 40mg
English: Figure C
Croatian: Slika C
English: Sodium dihydrogen phosphate dihydrate Disodium phosphate dihydrate Mannitol
Croatian: 6.1 Popis pomoćnih tvari natrijev dihidrogenfosfat dihidrat natrijev hidrogenfosfat dihidrat manitol natrijev klorid citratna kiselina hidrat natrijev citrat polisorbat 80
English: Table 12 Radiographic mean changes at week 52 in RA study V
Croatian: Tablica 12 Srednje vrijednosti promjena radioloških nalaza nakon 52 tjedna u ispitivanju RA V
English: Step 1 Prepare for your Injection
Croatian: 1. korak Pripremite se za injiciranje
English: Kromeya 40 mg/0.8 mL solution for injection (injection) for paediatric use is supplied as a sterile 0.8 mL clear, colourless solution of 40 mg adalimumab.
Croatian: Kromeya 40 mg/0,8 ml otopina za injekciju (injekcija) za pedijatrijsku uporabu dolazi kao sterilna bistra, bezbojna otopina s 40 mg adalimumaba u 0,8 ml otopine.
English: Children and adolescents from 4 to 17 years of age weighing 15 kg to less than 30 kg
Croatian: Djeca i adolescenti u dobi od 4 do 17 godina, tjelesne težine od 15 kg do manje od 30 kg
English: • 80 mg at week 0 and 40 mg at week 2
Croatian: • 80 mg u nultom tjednu i 40 mg u drugom tjednu
English: In patients with Crohn's disease, the loading dose of 80 mg adalimumab on week 0 followed by 40 mg adalimumab on week 2 achieves serum adalimumab trough concentrations of approximately 5.5 µg/mL during the induction period.
Croatian: Tijekom razdoblja indukcije u bolesnika s Crohnovom bolešću, nakon udarne doze od 80 mg adalimumaba u nultom tjednu i zatim 40 mg u 2. tjednu postignute su najniže serumske koncentracije adalimumaba od približno 5,5 μg/ml.
English: Transparent syringe housing
Croatian: Prozirno kućište štrcaljke
English: Table 18 Ps Study II (CHAMPION) efficacy results at 16 weeks
Croatian: Ps II (CHAMPION) Rezultati djelotvornosti nakon 16 tjedana
English: Hidradenitis suppurativa
Croatian: • gnojnog hidradenitisa
English: Warning: Do not throw away the pre-filled pen in your household trash.
Croatian: Upozorenje: Nemojte bacati brizgalicu u kućni otpad.
English: The recommended dose of Kromeya for patients with enthesitis-related arthritis from 6 years of age is based on body weight (Table 2).
Croatian: Preporučena doza lijeka Kromeya za bolesnike s artritisom povezanim s entezitisom u dobi od 6 i više godina određuje se na temelju tjelesne težine (Tablica 2).
English: If your child has mild heart failure and is being treated with Kromeya, his/her heart failure status must be closely monitored by your doctor.
Croatian: • Ako je Vaše dijete bolovalo ili boluje od ozbiljne srčane bolesti, važno je da to kažete svome liječniku Boluje li od blagog zatajenja srca, a liječi se lijekom Kromeya, liječnik mora pomno nadzirati status zatajenja srca..
English: The recommended dose of Kromeya for adult patients is an initial dose of 80 mg administered subcutaneously, followed by 40 mg subcutaneously given every other week starting one week after the initial dose.
Croatian: U odraslih bolesnika preporučena početna doza lijeka Kromeya je 80 mg supkutano, nakon čega slijedi 40 mg supkutano svaka dva tjedna, počevši jedan tjedan nakon početne doze.
English: Children and adolescents from 4 to 17 years of age weighing 30 kg or more
Croatian: Djeca i adolescenti u dobi od 4 do 17 godina, tjelesne težine 30 kg ili više
English: Significant improvement of signs of inflammation as measured by hs-CRP and MRI of both Sacroiliac Joints and the Spine was maintained in adalimumab-treated patients through week 156 and week 104, respectively.
Croatian: Među bolesnicima liječenima adalimumabom, značajno poboljšanje znakova upale, određeno razinom C-reaktivnog proteina visoke osjetljivosti (hs-CRP) i MR oslikavanjem i sakroilijakalnih zglobova i kralježnice, održalo se do 156. odnosno 104. tjedna.
English: Continued therapy beyond 16 weeks should be carefully reconsidered in a patient not responding within this time period.
Croatian: U slučaju da ni nakon 16 tjedana nema odgovora na liječenje, potrebno je pomno razmotriti nastavak liječenja takvog bolesnika.
English: Adalimumab 40 mg eow N=108 n (%)
Croatian: Adalimumab 40 mg svaki drugi tjedan, N=108 n (%)
English: It is important that you tell your doctor if your child has symptoms of infections, e.g. fever, wounds, feeling tired, dental problems (see “Warnings and precautions”).
Croatian: Ako Vaše dijete ima simptome infekcije, poput vrućice, rana, osjećaja umora, problema sa zubima, važno je da to kažete svom liječniku (vidjeti dio „Upozorenja i mjere opreza“).
English: Adult plaque psoriasis
Croatian: Plak psorijaza u odraslih
English: Paediatric plaque psoriasis Age or body weight
Croatian: Plak psorijaza u pedijatrijskoj populaciji Dob ili tjelesna težina
English: Adalimumab significantly delayed the time to treatment failure, as compared to placebo (See Figure 1, P < 0.0001 from log rank test).The median time to treatment failure was 24.1 weeks for subjects treated with placebo, whereas the median time to treatment failure was not estimable for subjects treated with adalimumab because less than one-half of these subjects experienced treatment failure.
Croatian: Medijan vremena do neuspjeha liječenja iznosio je 24,1 tjedan u ispitanika koji su primali placebo, dok se u ispitanika liječenih adalimumabom medijan vremena do neuspjeha liječenja nije mogao procijeniti jer je do neuspjeha liječenja došlo u manje od polovice tih ispitanika.
English: Glucocorticoids, salicylates, nonsteroidal anti-inflammatory drugs, or analgesics can be continued during treatment with Kromeya.
Croatian: Za vrijeme liječenja lijekom Kromeya može se nastaviti s davanjem glukokortikoida, salicilata, nesteroidnih protuupalnih lijekova ili analgetika.
English: There is insufficient evidence of the efficacy of Kromeya in patients with ankylosing spondylitis-like psoriatic arthropathy due to the small number of patients studied.
Croatian: Zbog premalog broja bolesnika uključenih u ispitivanje, nema dovoljno dokaza o djelotvornosti adalimumaba u liječenju bolesnika s psorijatičnom artropatijom sličnoj ankilozantnom spondilitisu.
English: Figure 1: Kaplan-Meier curves summarizing time to treatment failure in the paediatric uveitis study
Croatian: Slika 1: Kaplan-Meierove krivulje koje sažeto prikazuju vrijeme do neuspjeha liječenja u ispitivanju liječenja uveitisa u djece
English: • Keep the Kromeya pre-filled pen out of the reach of children.
Croatian: • Čuvajte Kromeya napunjenu brizgalicu izvan dohvata i pogleda djece.
English: The safety and efficacy of adalimumab were assessed in over 1500 patients with moderately to severely active Crohn's disease (Crohn's Disease Activity Index (CDAI) ≥ 220 and ≤ 450) in randomised, double-blind, placebo-controlled studies.
Croatian: Djelotvornost i sigurnost adalimumaba ocjenjivale su se u randomiziranim, dvostruko slijepim, placebom kontroliranim ispitivanjima u više od 1500 bolesnika s umjerenom do teškom aktivnom Crohnovom bolešću (indeks aktivnosti Chronove bolesti [engl.
English: What you need to know before you use Kromeya
Croatian: Što morate znati prije nego počnete primjenjivati lijek Kromeya Nemojte primjenjivati lijek Kromeya:
English: Kromeya 40 mg/0.8 mL solution for injection for paediatric use
Croatian: Kromeya 40 mg/0,8 ml otopina za injekciju za pedijatrijsku uporabu
English: Erosion score JSN
Croatian: pvrijednost ukupan zbroj bodova prema Sharpu c rezultat za eroziju JSN
English: Plaque psoriasis Age or body weight
Croatian: Plak psorijaza Dob ili tjelesna težina
English: Opportunistic infections, including invasive fungal infections have been observed in patients receiving adalimumab.
Croatian: U bolesnika koji primaju adalimumab zabilježene su oportunističke infekcije, uključujući invazivne gljivične infekcije.
English: The recommended dose of Kromeya for patients with polyarticular juvenile idiopathic arthritis from 2 years of age is based on body weight (Table 1).
Croatian: Poliartikularni juvenilni idiopatski artritis u dobi od 2 i više godina Preporučena doza lijeka Kromeya za bolesnike s poliartikularnim juvenilnim idiopatskim artritisom u dobi od 2 i više godina određuje se na temelju tjelesne težine (Tablica 1).
English: PsA study II
Croatian: Ispitivanje PsA II
English: Solution for injection 2 pre-filled pens 2 alcohol pads 6 pre-filled pens 6 alcohol pads
Croatian: 2 napunjene štrcaljke 2 jastučića natopljena alkoholom 6 napunjenih štrcaljki 6 jastučića natopljena alkoholom
English: Warning: Do not touch the syringe tip.
Croatian: Upozorenje: Ne dodirujte vrh štrcaljke.
English: Warning: Do not remove the clear needle cap.
Croatian: Upozorenje: Nemojte skidati prozirni poklopac s igle.
English: Step 7 Throw away your Pre-filled pen
Croatian: 7. korak Bacite brizgalicu
English: 40 mg Adalimumab every other week
Croatian: 40 mg Adalimumab svaki drugi tjedan
English: Plunger Rod
Croatian: Štapić klipa
English: Table 6 Undesirable effects
Croatian: Tablica 6 Nuspojave
English: • paediatric Crohn's disease
Croatian: • Crohnove bolesti
English: Syringe
Croatian: Cjepivo
English: • Store the pre-filled syringe in its original box to protect it from light.
Croatian: • Čuvajte napunjenu štrcaljku u originalnoj kutiji radi zaštite od svjetla.
English: Across all treatment groups, the mean baseline PASI score was 19.7 and the baseline PGA score ranged from “mild” (< 1%) to “moderate” (48%) to “severe” (46%) to “very severe” (6%).
Croatian: Srednja početna vrijednost PASI rezultata u svih ispitanih skupina iznosila je 19,7 a početni PGA rezultat kretao se u rasponu od „blagog“ (< 1%), preko „umjerenog“ (48%) do „teškog“ (46%) i „vrlo teškog“ (6%).
English: Erosion score
Croatian: Mjera ishoda
English: If this dose does not work well enough, your doctor may increase the dose frequency to 20 mg every week.
Croatian: Ako ova doza ne djeluje dovoljno dobro, liječnik Vam može povećati doziranje na 20 mg svaki tjedan..
English: In RA study V with early rheumatoid arthritis patients who were methotrexate naïve, combination therapy with adalimumab and methotrexate led to faster and significantly greater ACR responses than methotrexate monotherapy and adalimumab monotherapy at week 52 and responses were sustained at week 104 (see Table 10).
Croatian: U ispitivanju RA V, u kojem su obuhvaćeni bolesnici u ranoj fazi reumatoidnog artritisa koji do tada nisu bili liječeni metotreksatom, kombiniranom primjenom adalimumaba i metotreksata tijekom 52 tjedna postignut je brži i statistički značajno bolji ACR odgovor nego uz monoterapiju metotreksatom, odnosno adalimumabom.
English: • low blood measurements for red blood cells;
Croatian: • niska razina bijelih krvnih stanica, crvenih krvnih stanica i krvnih pločica.
English: Pulmonary fibrosis
Croatian: • plućna fibroza (ožiljci na plućima),
English: In Study nr-axSpA I, adalimumab 40 mg every other week was assessed in 185 patients in one randomised, 12 week double-blind, placebo-controlled study in patients with active nr-axSpA (mean baseline score of disease activity [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)] was 6.4 for patients treated with adalimumab and 6.5 for those on placebo) who have had an inadequate response to or intolerance to ≥ 1 NSAIDs, or a contraindication for NSAIDs.
Croatian: Bath Ankylosing Spondilitis Disease Activity Index, BASDAI)] bila je 6,4 u skupini bolesnika koji su primali adalimumab i 6,5 u skupini koja je primala placebo) koji nisu imali zadovoljavajući odgovor na  1 NSAIL-a ili ga nisu podnosili, ili su imali kontraindikaciju za primjenu NSAIL-a.
English: Vertigo and visual impairment may occur following administration of Kromeya (see section 4.8).
Croatian: Nakon primjene lijeka Kromeya mogu se pojaviti vrtoglavica i poremećaji vida (vidjeti dio 4.8).
English: Your child is advised to avoid becoming pregnant and must use adequate contraception while using Kromeya and for at least 5 months after the last Kromeya injection.
Croatian: Preporučuje se da za vrijeme korištenja lijeka Kromeya Vaše dijete ne ostane trudno te da još barem 5 mjeseci nakon posljednje injekcije lijeka Kromeya koristi odgovarajuću kontracepciju.
English: It is important that you tell your doctor if you have symptoms of infections, e.g. fever, wounds, feeling tired, dental problems (see “Warnings and precautions”).
Croatian: Ako imate simptome infekcije, poput vrućice, rana, osjećaja umora, problema sa zubima, važno je da to kažete svom liječniku (vidjeti dio „Upozorenja i mjere opreza“).
English: In CD study I and CD study II, statistically significant improvement in the disease-specific inflammatory bowel disease questionnaire (IBDQ) total score was achieved at week 4 in patients randomised to adalimumab 80/40 mg and 160/80 mg compared to placebo and was seen at weeks 26 and 56 in CD study III as well among the adalimumab treatment groups compared to the placebo group.
Croatian: U 4. tjednu ispitivanja CD I i CD II, u bolesnika koji su randomizirani za primanje adalimumaba 80/40 mg i adalimumaba 160/80 mg došlo je do statistički značajnog poboljšanja ukupnog rezultata prema upitniku o upalnoj bolesti crijeva (engl.
English: If you have mild heart failure and you are being treated with Kromeya, your heart failure status must be closely monitored by your doctor.
Croatian: • Ako ste bolovali ili bolujete od ozbiljne srčane bolesti, važno je da to kažete svome liječniku Bolujete li od blagog zatajenja srca, a liječite se lijekom Kromeya, liječnik mora pomno nadzirati status zatajenja srca..
English: In adult patients with ulcerative colitis, a loading dose of 160 mg adalimumab on week 0 followed by 80 mg adalimumab on week 2 achieves serum adalimumab trough concentrations of approximately 12 µg/mL during the induction period.
Croatian: Tijekom razdoblja indukcije u odraslih bolesnika s ulceroznim kolitisom, nakon udarne doze od 160 mg adalimumaba u nultom tjednu i zatim 80 mg u drugom tjednu postignute su najniže serumske koncentracije adalimumaba od oko 12 μg/ml.
English: Kromeya 40 mg/0.8 mL solution for injection for paediatric use adalimumab
Croatian: Kromeya 40 mg/0,8 ml otopina za injekciju za pedijatrijsku uporabu adalimumab
English: Kromeya 40 mg solution for injection in pre-filled syringe adalimumab
Croatian: Kromeya 40 mg otopina za injekciju u napunjenoj štrcaljki adalimumab
English: If a faster response is required, your child's doctor may prescribe an initial dose of 160 mg (as four 40 mg injections in
Croatian: Ako je potreban brži odgovor na liječenje, liječnik može propisati početnu dozu od 80 mg (u
English: Lymphoma**, solid organ neoplasm (including breast cancer, lung neoplasm and thyroid neoplasm), melanoma**
Croatian: često rak kože, isključujući melanom (uključujući bazocelularni karcinom i karcinom skvamoznih stanica), benigne neoplazme manje često limfom**, novotvorine na solidnim organima (uključujući rak dojke, novotvorine na plućima i štitnjači), melanom**
English: Of 207 patients who were randomised to adalimumab 40mg every other week, 114 patients continued on adalimumab 40 mg every other week for 5 years.
Croatian: Kroz 5 godina, terapiju adalimumabom 40 mg svaka dva tjedna nastavilo je 114 od 207 bolesnika koji su bili randomizirani u skupinu koja je primala adalimumab 40 mg svaki drugi tjedan.
English: Warning: Do not reuse a syringe in case of partial injection.
Croatian: Upozorenje: Nemojte ponovno upotrebljavati štrcaljku za koju ste primijetili da je sadržaj samo djelomično injiciran.