FrancophonIA/ELRC3.0 huggingface dataset:
English: NAME OF THE MEDICINAL PRODUCT Leflunomide medac 10 mg film-coated tablets
Danish: LÆGEMIDLETS NAVN Leflunomide medac 10 mg filmovertrukken tablet
English: NAME OF THE MEDICINAL PRODUCT Leflunomide medac 15 mg film-coated tablets
Danish: LÆGEMIDLETS NAVN Leflunomide medac 15 mg filmovertrukken tablet
English: Leflunomide medac 15 mg film-coated tablets are white to almost white and round with a diameter of about 7 mm. One side of the tablet is debossed with “15”.
Danish: Leflunomide medac 15 mg filmovertrukne tabletter er hvide til næsten hvide og runde med en diameter på ca. 7 mm.
English: The time to peak plasma concentrations of A771726 is very variable; peak plasma levels can occur between 1 hour and 24 hours after single administration.
Danish: Maksimale plasmakoncentrationer kan indtræde mellem 1 - 24 timer efter indgift af enkeltdosis.
English: • tiredness (asthenia),
Danish: • slaphed (asteni),
English: pancreatitis
Danish: Dosering
English: • abdominal pain,
Danish: • mavesmerter,
English: Date of first authorisation: 4 March 2003 Date of latest renewal: 4 March 2008
Danish: Dato for første markedsføringstilladelse: 4. marts 2003 Dato for seneste fornyelse: 4. marts 2008
English: Vivanza with food, drink and alcohol
Danish: Brug af Vivanza sammen med mad, drikke og alkohol
English: ANNEX II A. MANUFACTURER RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION D. CONDITION OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE USE OF THE MEDICINAL PRODUCT
Danish: BILAG II A. FREMSTILLER ANSVARLIG FOR BATCHFRIGIVELSE B. BETINGELSER ELLER BEGRÆNSNINGER VEDRØRENDE UDLEVERING OG ANVENDELSE C. ANDRE FORHOLD OG BETINGELSER FOR MARKEDSFØRINGSTILLADELSEN D. BETINGELSER ELLER BEGRÆNSNINGER MED HENSYN TIL SIKKER OG EFFEKTIV ANVENDELSE AF LÆGEMIDLET
English: Stop taking Vivanza and contact your doctor immediately.
Danish: Stop med at tage Vivanza og kontakt øjeblikkeligt Deres læge.
English: Do not take Vivanza more than once a day.
Danish: De må ikke tageVivanza mere end én gang i løbet af døgnet.
English: Men who take too much Vivanza may experience more side effects or may get severe back pain.
Danish: Mænd, som tager for meget Vivanza, kan opleve flere bivirkninger eller få alvorlige rygsmerter.
English: - You can take Vivanza with or without food but preferably not after a heavy or high-fat meal as this may delay the effect.
Danish: - De kan tage Vivanza uafhængigt af måltider, men helst ikke efter et massivt måltid eller et meget fedtholdigt måltid, da det kan forsinke virkningen.
English: - Don't drink grapefruit juice when you use Vivanza.
Danish: - Drik ikke grapefrugtjuice, når De bruger Vivanza.
English: Tell your doctor if you think Vivanza is too strong or too weak.
Danish: Tal med Deres læge, hvis De mener, at Vivanza er for kraftige eller for svage.
English: Vivanza allows an erection to last long enough for you to satisfactorily complete sexual activity.
Danish: Vivanza lader en erektion vare længe nok til, at De på tilfredsstillende måde kan gennemføre en seksuel aktivitet.
English: Effects on the QT interval were measured one hour post-dose (average tmax for vardenafil).
Danish: Påvirkninger af QT-intervallet blev målt en time efter dosering (gennemsnitlig tmax for vardenafil).
English: Due to the nitrate component, it has the potential to have serious interaction with vardenafil.
Danish: På grund af nitratkomponenten kan det potentielt have alvorlige interaktioner med vardenafil.
English: Parts of M1 are in the form of the glucuronide in systemic circulation.
Danish: En del af M1 er på glukuronid-form i den systemiske cirkulation .
English: In order for Vivanza to be effective, sexual stimulation is required.
Danish: For at Vivanza kan være effektiv, er seksuel stimulation nødvendig.
English: The tablets are provided in blister packs containing 2, 4, 8, 12 or 20 tablets.
Danish: Tabletterne findes i blisterpakninger, som indeholder 2, 4, 8, 12 eller 20 tabletter.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Danish: Indehaveren af markedsføringstilladelsen skal udføre de påkrævede laktiviteter og foranstaltninger vedrørende lægemiddelovervågning, som er beskrevet i den godkendte RMP, der fremgår af modul 1.8.2 i markedsføringstilladelsen, og enhver efterfølgende godkendt opdatering af RMP.
English: Talk to a doctor without taking Vivanza.
Danish: Tal med en læge uden at tage Vivanza.
English: PP/Aluminium foil blisters in cartons of 2, 4, 8, 12 and 20 tablets.
Danish: PP/aluminiumsfolie-blisters i pakninger med 2, 4, 8, 12 og 20 tabletter.
English: Taking these medicines with Vivanza could seriously affect your blood pressure.
Danish: Indtagelse af denne medicin sammen med Vivanza kan have en alvorlig påvirkning på Deres blodtryk.
English: Vivanza might make some people feel dizzy or affect their vision.
Danish: Vivanza kan medføre svimmelhed eller synspåvirkning hos nogle.
English: If you feel dizzy, or if your vision is affected after taking Vivanza don't drive or operate any tools or machines.
Danish: Hvis De føler Dem svimmel eller Deres syn er påvirket efter at have taget Vivanza, bør De ikke køre bil eller betjene maskiner.
English: Contents of the pack and other information What Vivanza contains
Danish: Pakningsstørrelser og yderligere oplysninger Vivanza indeholder:
English: At tmax, only the mean change in QTcF for vardenafil 80 mg was out of the study established limit (mean 10 msec, 90% CI: 8-11).
Danish: Ved tmax var kun ændringen i middelværdi for QTcF for 80 mg vardenafil udenfor den i studiet fastsatte grænse (middelværdi 10 msek, 90% CI: 8-11).
English: Vivanza will only work when you are sexually stimulated.
Danish: Vivanza fungerer kun i forbindelse med seksuel stimulation.
English: With sexual stimulation, you may achieve an erection anywhere from 25 minutes up to four to five hours after taking Vivanza.
Danish: I forbindelse med seksuel stimulation kan De opnå en erektion i tidsrummet fra 25 minutter op til 4-5 timer efter at have taget Vivanza.
English: The maximum dose for Vivanza orodispersible tablet is 10 mg/day.
Danish: Den maksimale dosis af Vivanza smeltetablet er 10 mg/dag.
English: What you need to know before you take Vivanza Do not take Vivanza
Danish: Det skal De vide, før De begynder at tage Vivanza Tag ikke Vivanza
English: The primary objective of this study was to rule out a greater than 10 msec effect (i.e. to demonstrate lack of effect) of a single 80 mg oral dose of vardenafil on QTc interval compared to placebo, as measured by the change in Fridericia's correction formula (QTcF=QT/RR1/3) from baseline at the 1 hour post-dose time point.
Danish: Det primære formål med dette studie var at udelukke en effekt større end 10 msek (dvs. påvise manglende effekt) på QTc-intervallet med en enkelt oral dosis på 80 mg vardenafil sammenlignet med placebo, målt som ændringen i Fridericia's korrektionsformel (QTcF=QT/RR1/3) en time efter dosering, sammenlignet med udgangsværdien.
English: If you are allergic to vardenafil or any of the other ingredients of this medicine (listed in section 6).
Danish: - Hvis De er allergisk over for vardenafil eller et af de øvrige indholdsstoffer i Vivanza (angivet i punkt 6).
English: The adverse reactions reported with Vivanza film-coated tablets or 10 mg orodispersible tablets in clinical trials were generally transient and mild to moderate in nature.
Danish: De bivirkninger, der blev indberettet med Vivanza filmovertrukne tabletter eller 10 mg smeltetabletter i kliniske studier, var generelt forbigående og lette til moderate.
English: He or she may suggest a switch to an alternative vardenafil formulation with a different dose, depending on how well it works for you.
Danish: Lægen kan da foreslå, at De skifter til en anden formulering af vardenafil med en anden dosis, afhængigt af hvordan virkningen er på Dem.
English: There are no data on the interaction of vardenafil and non-specific phosphodiesterase inhibitors such as theophylline or dipyridamole.
Danish: Der findes ikke data for interaktion mellem vardenafil og non-specifikke phosphodiesterase-inhibitorer som theofyllin eller dipyridamol.
English: Visual defects and cases of non-arteritic ischemic optic neuropathy (NAION) have been reported in connection with the intake of Vivanza and other PDE5 inhibitors.
Danish: Der er rapporteret synsdefekter og tilfælde af non-arteritis anterior iskæmisk opticusneuropati (NAION) i forbindelse med indtagelse af Vivanza og andre PDE5-hæmmere.
English: In humans the one major circulating metabolite (M1) results from desethylation of vardenafil and is subject to further metabolism with a plasma elimination half-life of approximately 4 hours.
Danish: Hos mennesker er den væsentligste cirkulerende metabolit (M1) et resultat af en deethylering af vardenafil og er underlagt yderligere metabolisme med en plasma-eliminationshalveringstid på ca. fire timer.
English: In the small number of patients who attempted intercourse up to four to five hours after dosing the success rate for penetration and maintenance of erection was consistently greater than placebo.
Danish: Hos det begrænsede antal patienter som forsøgte samleje op til fire til fem timer efter indtagelse af dosis var succesraten for penetration og vedligeholdelse af erektion konsistent større end for placebo.
English: Medicinal products for the treatment of erectile dysfunction should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie's disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia).
Danish: Lægemidler til behandling af erektil dysfunktion bør anvendes med forsigtighed hos patienter med anatomisk deformitet af penis (som f.eks. vinkling, kavernøs fibrose eller Peyronie's sygdom), eller hos patienter med lidelser, som kan prædisponere til priapisme (som f.eks. seglcellanæmi, multipelt myelom eller leukæmi).
English: Vivanza is not indicated for use by women.
Danish: Vivanza er ikke indiceret til anvendelse hos kvinder.
English: Vivanza 10 mg orodispersible tablets are round and white.
Danish: Vivanza 10 mg smeltetabletter er runde og hvide.
English: Vivanza contains vardenafil, a member of a class of medicines called phosphodiesterase type 5 inhibitors.
Danish: Vivanza indeholder vardenafil og tilhører en gruppe lægemidler, der kaldes fosfodiesterase type 5hæmmere.
English: In vitro studies with human platelets indicate that vardenafil has no antiaggregatory effect on its own, but at high (super-therapeutic) concentrations, vardenafil potentiates the antiaggregatory effect of the nitric oxide donor sodium nitroprusside.
Danish: In vitro-undersøgelser med humane blodplader indikerer at vardenafil ikke har antiaggregatorisk effekt i sig selv men ved høje (over-terapeutiske) koncentrationer forstærker vardenafil den antiaggregatoriske effekt af nitrogenoxiddonoren natriumnitroprussid.
English: Whatever the cause is, due to muscle and blood vessel changes not enough blood stays in the penis to make it hard and keep it hard.
Danish: Uanset årsagen er virkningen den samme: Muskel- og blodkarsændringer gør, at der ikke er tilstrækkeligt blod i penis til at opnå og bevare stivhed.
English: - If you are taking medicines containing nitrates, such as glycerol trinitrate for angina, or nitric oxide donors, such as amyl nitrite.
Danish: - Hvis De tager medicin, som indeholder nitrater, som nitroglycerin for angina, eller nitrogenoxid donorer som amylnitrit.
English: Metabolite M1 shows a phosphodiesterase selectivity profile similar to vardenafil and an in vitro potency for phosphodiesterase type 5 of approximately 28% compared to vardenafil, resulting in an efficacy contribution of about 7%.
Danish: Metabolitten M1 udviser en phosphodiesterase selektivitetsprofil svarende til vardenafil og en in vitro-styrke over for phosphodiesterase type 5 på ca. 28% sammenlignet med vardenafil, resulterende i et effektbidrag på ca.
English: Talk to your doctor or pharmacist before taking Vivanza.
Danish: Kontakt lægen eller apotekspersonalet, før De tager Vivanza.
English: A starting dose of 5 mg should be considered in patients with mild and moderate hepatic impairment (Child-Pugh A-B).
Danish: En startdosis på 5 mg bør overvejes hos patienter med let og moderat nedsat leverfunktion (Child-Pugh A-B).
English: It may be harmful for people with phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.
Danish: Det kan være skadeligt for personer med phenylketonuri (PKU, Føllings sygdom), en sjælden genetisk lidelse, hvor phenylalanin ophobes, fordi kroppen ikke kan fjerne det ordentligt.
English: See section 2 “Vivanza 10 mg orodispersible tablets contain Aspartame and Sorbitol”.
Danish: Se punkt 2 ”Vivanza 10 mg smeltetabletter indeholder aspartam og sorbitol”.
English: No effect on blood pressure was observed when nitroglycerin was taken 24 hours after administration of a single dose of vardenafil 20 mg film-coated tablets.
Danish: Der sås ingen effekt på blodtrykket, når nitroglycerin blev indtaget 24 timer efter administration af en enkelt dosis vardenafil 20 mg filmovertrukne tabletter.
English: Vardenafil is rapidly absorbed after administration of Vivanza 10 mg orodispersible tablets without water.
Danish: Vardenafil absorberes hurtigt efter indgift af Vivanza 10 mg smeltetabletter uden vand.
English: Vardenafil causes mild and transient decreases in blood pressure, which in the majority of the cases, do not translate into clinical effects.
Danish: Vardenafil forårsager let og forbigående blodtryksfald, der i de fleste tilfælde ikke kommer til udtryk som klinisk virkning.
English: The mean terminal half-life of vardenafil in patients receiving Vivanza 10 mg orodispersible tablets ranged between 4 - 6 hours.
Danish: Den gennemsnitlige terminale halveringstid for vardenafil hos patienter, der fik Vivanza 10 mg smeltetabletter, var mellem 4-6 timer.
English: They are provided in packs of 4 x 1 orodispersible tablets in alu/alu perforated unit dose blisters.
Danish: De findes i pakninger, som indeholder 4 x 1 smeltetabletter på alu/alu perforeret enkeltdosisblister.
English: Gastrointestinal and abdominal pain
Danish: Gastointestinale smerter og abdominalsmerter Diaré
English: It may be risky for you to have sex. - If you suffer from irregular heart beat (cardiac arrhythmia) or inherited heart diseases affecting your electrocardiogram.
Danish: Det kan være risikabelt for Dem at have sex. - Hvis De lider af hjerterytmeforstyrrelser eller en medfødt hjertesygdom, der påvirker Deres elektrokardiogram.
English: 4 x 1 orodispersible tablets in alu/alu perforated unit dose blisters.
Danish: 4 x 1 smeltetabletter i alu/alu perforeret enkeltdosisblister.
English: - You can take Vivanza orodispersible tablets with or without food but do not take this medicine with any liquid.
Danish: - De kan tage Vivanza smeltetabletter uafhængigt af måltider, men tag ikke medicinen sammen med væske.
English: EU/1/03/249/016 4 tablets
Danish: EU/1/03/249/016 4 tabletter
English: Vivanza is not intended for use by children or adolescents under 18.
Danish: Vivanza er ikke beregnet til børn og unge under 18 år.
English: 4 x 1 orodispersible tablets
Danish: 4 x 1 smeltetabletter
English: No clinical trials in CNS diseases (except spinal cord injury), patients with severe renal or hepatic impairment, pelvic surgery (except nerve-sparing prostatectomy) or trauma or radiotherapy and hypoactive sexual desire or penile anatomic deformities have been performed.
Danish: Der er ikke foretaget kliniske studier med patienter med CNSsygdomme (undtagen rygmarvsskader), stærkt nedsat nyre- eller leverfunktion, bækkenkirurgi (med undtagelse af nervebesparende prostatektomi) eller trauma eller strålebehandling og hypoaktiv seksuel lyst eller anatomiske penisdeformationer.
English: In those patients who are stable on alpha-blocker therapy, vardenafil should be initiated at the lowest recommended starting dose of 5 mg. Vivanza may be administered at any time with tamsulosin or alfuzosin.
Danish: Hos de patienter, der er i stabil alfa-blokker-behandling, bør vardenafil initieres med den laveste anbefalede startdosis på 5 mg. Vivanza kan administreres på et hvilket som helst tidspunkt med tamsulosin eller med alfuzosin.
English: As this may be relevant for all patients exposed to vardenafil the patient should be advised that in the case of sudden visual defect, he should stop taking Vivanza and consult immediately a physician (see section 4.3).
Danish: Da dette kan være relevant for alle patienter, som eksponeres for vardenafil, skal patienten informeres om, at han skal stoppe med at tage Vivanza og omgående konsultere en læge, hvis der pludseligt opstår synsdefekt (se pkt.
English: Non-arteritic anterior ischemic optic neuropathy Visual defects
Danish: Non-arteritis anterior iskæmisk opticusneuropati Synsdefekt
English: Vivanza is not for use by women.
Danish: Vivanza er ikke beregnet til brug hos kvinder.
English: There is no relevant indication for use of Vivanza orodispersible tablets in children and adolescents.
Danish: Der er ingen relevante indikationer for brug af Vivanza smeltetabletter til børn og unge.
English: In patients with severe renal impairment (creatinine clearance <30 ml/min), a starting dose of 5 mg should be considered.
Danish: Hos patienter med stærk nedsat nyrefunktion (kreatininclearance <30 ml/min) bør en startdosis på 5 mg overvejes.
English: Photosensitivity reaction
Danish: Fotosensitivitetsreakti oner
English: Vivanza is not indicated for individuals below 18 years of age.
Danish: Vivanza er ikke indiceret til personer under 18 år.
English: As dizziness and abnormal vision have been reported in clinical trials with vardenafil, patients should be aware of how they react to Vivanza, before driving or operating machines.
Danish: Da der er rapporteret svimmelhed og abnormt syn i kliniske undersøgelser med vardenafil, bør patienter være opmærksomme på, hvordan de reagerer på Vivanza, inden de kører bil og betjener maskiner.
English: As this may be relevant for all patients exposed to vardenafil the patient should be advised that in the case of sudden visual defect, he should stop taking Vivanza orodispersible tablets and consult immediately a physician (see section 4.3).
Danish: Da dette kan være relevant for alle patienter, som eksponeres for vardenafil, skal patienten informeres om, at han skal stoppe med at tage Vivanza smeltatablet og omgående konsultere en læge, hvis der pludseligt opstår synsdefekt (se pkt.
English: Use in patients using other medicinal products Concomitant use of moderate or potent CYP3A4 inhibitors Vardenafil dose adjustment is necessary if moderate or potent CYP3A4 inhibitors are given concomitantly (see section 4.5).
Danish: Anvendelse hos patienter, som anvender anden medicin Samtidig anvendelse af moderate eller potente CYP3A4-inhibitorer Dosisjustering af vardenafil er nødvendig, hvis det gives sammen med moderate eller potente CYP3A4inhibitorer (se pkt.
English: There is no relevant indication for use of Vivanza in children.
Danish: Der er ingen relevante indikationer for brug af Vivanza til børn.
English: At a dose of 20 mg Vivanza film-coated tablets, elderly (≥65 years old) patients had higher frequencies of headaches (16.2% versus 11.8%) and dizziness (3.7% versus 0.7%) than younger patients (<65 years old).
Danish: Ved en dosis på 20 mg Vivanza filmovertrukne tabletter fik ældre patienter (≥65 år) hyppigere hovedpine (16,2% sammenlignet med 11,8%) og svimmelhed (3,7% sammenlignet med 0,7%) end yngre patienter (<65 år).
English: Visual disturbance Ocular hyperaemia Visual colour distortions Eye pain and eye discomfort Photophobia
Danish: Synsforstyrrelser Okulær hyperæmi Ændret farvesyn Øjensmerter og ubehag i øjet Fotofobi
English: Vivanza 10 mg orodispersible tablets contain Aspartame and Sorbitol.
Danish: Vivanza 10 mg smeltetabletter indeholder aspartam og sorbitol:
English: Take special care with Vivanza
Danish: Vær ekstra forsigtig med at tage Vivanza
English: Vivanza orodispersible tablets must be taken without liquid and immediately upon release from the blister.
Danish: Vivanza smeltetabletter skal indtages uden væske straks efter, at den er taget ud af blisterpakningen.
English: As dizziness and abnormal vision have been reported in clinical trials with vardenafil, patients should be aware of how they react to Vivanza orodispersible tablets, before driving or operating machines.
Danish: Da der er rapporteret svimmelhed og abnormt syn i kliniske undersøgelser med vardenafil, bør patienter være opmærksomme på, hvordan de reagerer på Vivanza smeltetabletter, inden de kører bil og betjener maskiner.
English: Patients treated with alpha-blockers should not use Vivanza 10 mg orodispersible tablets as a starting dose.
Danish: Patienter, der bliver behandlet med alfa-blokker, bør ikke anvende Vivanza 10 mg smeltetabletter som startdosis.
English: Sleep disorder
Danish: Søvnforstyrrelser Angst
English: Take a Vivanza tablet about 25 to 60 minutes before sexual activity.
Danish: Tag en Vivanza-tablet cirka 25 til 60 minutter før seksuel aktivitet.
English: Vivanza 10 mg orodispersible tablets are not indicated as a starting dose in patients with mild hepatic impairment (Child-Pugh A).
Danish: Vivanza 10 mg smeltetabletter er ikke beregnet som startdosis til patienter med let nedsat leverfunktion (Child-Pugh A).
English: He or she may suggest a switch to an alternative Vivanza formulation with a different dose, depending on how well it works for you.
Danish: Lægen kan da foreslå, at De skifter til en anden formulering af Vivanza med en anden dosis afhængigt af, hvordan virkningen er på Dem.
English: How to take Vivanza
Danish: Sådan skal De tage Vivanza
English: Patients with mild hepatic impairment should start treatment with Vivanza 5 mg film-coated tablets.
Danish: Patienter med let nedsat leverfunktion bør starte behandlingen med Vivanza 5 mg filmovertrukne tabletter.
English: Aspartame (E951) Peppermint flavour Magnesium stearate Crospovidone Mannitol (E421) Silica colloidal hydrated Sorbitol (E420)
Danish: Aspartam (E951) Pebermyntearoma Magnesiumstearat Crospovidon Mannitol (E421) Silica, kolloid vandfri Sorbitol (E420)
English: Magnesium stearate, aspartame (E951), peppermint flavour, mannitol (E421) sorbitol (E420), crospovidone and silica colloidal hydrated.
Danish: Magnesiumsterat, aspartam (E951), pebermyntearoma, mannitol (E421), sorbitol (E420), crospovidon og kolloid vandfri silica.
English: If Vivanza 10 mg orodispersible tablets are taken with water, the AUC is reduced by 29%, Cmax remains unchanged and median tmax is shortened by 60 minutes compared to intake without water.
Danish: Hvis Vivanza 10 mg smeltetabletter tages med vand, reduceres AUC med 29%, Cmax forbliver uændret, og den mediane tmax bliver nedsat med 60 min. sammenlignet med indgift uden vand.
English: The safety of vardenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated until further information is available: - severe hepatic impairment (Child-Pugh C), - end stage renal disease requiring dialysis, - hypotension (blood pressure <90/50 mmHg), - recent history of stroke or myocardial infarction (within the last 6 months), - unstable angina and known hereditary retinal degenerative disorders such as retinitis pigmentosa.
Danish: Sikkerheden af vardenafil er ikke undersøgt i følgende patientundergrupper, og dets anvendelse er derfor kontraindiceret indtil yderligere information er tilgængelig: - alvorlig leverinsufficiens (Child-Pugh C), - terminal nyresygdom med behov for dialyse, - hypotension (blodtryk < 90/50 mmHg), - nyligt overstået apopleksi eller hjerteinfarkt (inden for de sidste seks måneder), - ustabil angina pectoris og kendte arvelige degenerative sygdomme i retina som f.eks. retinitis pigmentosa.