FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients had received a median of 14 months of prior IFN therapy at doses  25 x 10
Danish: Patienterne havde i gennemsnit tidligere modtaget 14 måneders IFN-behandling med doser 25 x 10
English: At one year the overall RFS was significantly better for Glivec (97.7%) vs. placebo (82.3%), (p<0.0001).
Danish: På et år var den samlede RFS signifikant bedre for Glivec (97,7%) i forhold til placebo (82,3%), (p<0,0001).
English: Treatment with Glivec may be interrupted or the dose may be reduced, as recommended in section 4.2.
Danish: Behandling med Glivec kan seponeres eller dosis kan reduceres, som anbefalet i pkt.
English: In CML, cytopenias, particularly neutropenia and thrombocytopenia, have been a consistent finding in all studies, with the suggestion of a higher frequency at high doses  750 mg (phase I study).
Danish: Cytopeni hos CML-patienter, særligt neutropeni og trombocytopeni, har været gennemgående fund i alle undersøgelser med tegn på større hyppighed ved doser 750 mg (fase I undersøgelse).
English: It is important that you do this as long as your doctor or pharmacist tells you to.
Danish: Det er vigtigt at du tager det så længe, lægen eller apotekspersonalet fortæller dig, at du skal.
English: Treatment of CML patients with Glivec has been associated with neutropenia or thrombocytopenia.
Danish: Behandling af CML-patienter med Glivec har været associeret med neutropeni eller trombocytopeni.
English: This may be a sign of damage to blood vessels known as thrombotic microangiopathy
Danish: Dette kan være tegn på beskadigelse af dine blodkar, hvilket kaldes trombotisk mikroangiopati (TMA).
English: - Myelodysplastic/myeloproliferative diseases (MDS/MPD).
Danish: - Myelodysplastiske/myeloproliferative sygdomme (MDS/MDP).
English: A total of 71 (12.8%) and 85 (15.4%) patients died in the Glivec and IFN+Ara-C groups, respectively.
Danish: I alt døde 71 (12,8%) og 85 (15,4%) patienter i henholdsvis Glivec- og IFN+Ara-C-grupperne.
English: All patients received imatinib and consolidation chemotherapy (see Table 4) after induction and the levels of bcr-abl transcripts were identical in the two arms at 8 weeks.
Danish: Alle patienter blev efter induktion behandlet med imatinib og standard kemoterapi (se Tabel 4), og bcr-abl transkriptionerne var identiske i de to arme efter 8 ugers behandling.
English: (0.5 h), days 7, 8, 14, 15;
Danish: (0,5 time), dag 7, 8, 14, 15;
English: Figure 1 Kaplan-Meier estimates for primary recurrence-free survival endpoint (ITT population)
Danish: Figur 1 Kaplan-Meier-endepunkts-estimater for primær recidivfri overlevelse (ITTpopulation)
English: Glivec is a treatment for adults and children for:
Danish: Glivec er en behandling til voksne og børn mod:
English: Caution should be taken when administering Glivec with inhibitors of the CYP3A4 family.
Danish: Forsigtighed bør udvises, når Glivec administreres sammen med hæmmere af CYP3A4-familien.
English: After resection of primary GIST, patients were randomised to one of the two arms: Glivec at 400 mg/day or matching placebo for one year.
Danish: Efter resektion af primær GIST blev patienterne randomiseret til en af de to behandlingsarme: Glivec 400 mg/dag eller tilsvarende placebo i et år.
English: C-labelled dose of imatinib, approximately 81% of the dose was recovered within 7 days in faeces (68% of dose) and urine (13% of dose).
Danish: C-mærket imatinib, genfandtes ca. 81% af dosis inden for 7 dage i fæces (68% af dosis) og urin (13% af dosis).
English: - Do not breast-feed during the treatment with Glivec.
Danish: - Du må ikke amme, mens du er i behandling med Glivec.
English: Elimination Based on the recovery of compound(s) after an oral
Danish: Elimination Baseret på fremkomne stof(fer) efter oral dosis af
English: Because of known increased risks of bleeding in conjunction with the use of imatinib (e.g. haemorrhage), patients who require anticoagulation should receive low-molecular-weight or standard heparin, instead of coumarin derivatives such as warfarin.
Danish: På grund af den øgede risiko for blødning ved brug af imatinib (f.eks. hæmoragi) bør patienter med behov for antikoagulantia have lavmolekylært heparin eller standardheparin i stedet for coumarinderivater som warfarin.
English: 12-month treatment arm 36-month treatment arm
Danish: 12 måneders behandlingsarm 36 måneders behandlingsarm
English: Haematological response Complete haematological response (CHR) No evidence of leukaemia (NEL)
Danish: Hæmatologisk respons Fuldstændigt hæmatologisk respons (CHR) Intet tegn på leukæmi (NEL)
English: In the Glivec arm, patients were treated with 400 mg daily.
Danish: I Glivec-armen blev patienterne behandlet med 400 mg daglig.
English: An observational registry (study L2401) was conducted to collect long-term safety and efficacy data in patients suffering from myeloproliferative neoplasms with PDGFR- β rearrangement and who were treated with Glivec.
Danish: Et observationelt registerstudie (studie L2401) blev udført for at indsamle langsigtede sikkerheds- og effektdata for patienter, som lider af myeloproliferative neoplasier med PDGFR- β rearrangement og som blev behandlet med Glivec.
English: With 7 years follow-up, there were 93 (16.8%) progression events in the Glivec arm: 37 (6.7%) involving progression to accelerated phase/blast crisis, 31 (5.6%) loss of MCyR, 15 (2.7%) loss of CHR or increase in WBC, and 10 (1.8%) CML unrelated deaths.
Danish: Ved 7-års opfølgning var der 93 (16,8%) progressionshændelser i Glivec-armen: 37 (6,7%) omhandlede progression til accelereret fase/blastkrise, 31 (5,6%) tab af MCyR, 15 (2,7%) tab af CHR eller stigning i WBC, og 10 (1,8%) dødsfald ikke relateret til CML.
English: Total bilirubin: >3-10 ULN AST: any ULN = upper limit of normal for the institution AST = aspartate aminotransferase
Danish: Total-bilirubin: >3-10 ULN ASAT: alt ULN = laboratoriets øvre normalgrænse ASAT = aspartataminotransferase
English: N.E.
Danish: I.E.
English: The 23 patients enrolled in this registry received Glivec at a median daily dose of 264 mg (range: 100 to 400 mg) for a median duration of 7.2 years (range 0.1 to 12.7 years).
Danish: De 23 patienter som var inkluderet i registerstudiet, fik Glivec med en daglig mediandosis på 264 mg (dosisområde: 100 til 400 mg) med en median varighed på 7,2 år (behandlingstid 0,1 til 12,7 år).
English: • Do not store above 30°C.
Danish: • Må ikke opbevares ved temperaturer over 30° C.
English: This time-to-event endpoint is strongly affected by the high crossover rate from IFN+Ara-C to Glivec.
Danish: Dette tid-til-hændelse effektmål er stærkt påvirket af det høje antal skift fra IFN+Ara-C-armen til Glivec-armen.
English: Alternating chemotherapy course: high dose chemotherapy with MTX 1 g/m i.v.
Danish: Supplerende kemoterapi omgange: høj-dosis kemoterapi med MTX 1 g/m i.v.
English: In the adjuvant setting, Glivec was investigated in a multicentre, double-blind, long-term, placebocontrolled phase III study (Z9001) involving 773 patients.
Danish: Som adjuverende behandling blev Glivec undersøgt i et multicenter, dobbeltblindet, længerevarende placebokontrolleret fase III klinisk forsøg (Z9001), der involverede 773 patienter.
English: In vitro, Glivec inhibits paracetamol O-glucuronidation with Ki value of 58.5 micromol/l.
Danish: In vitro hæmmer Glivec O-glucuronidationen af paracetamol med en Ki-værdi på 58,5 mikromol/l.
English: If a severe non-haematological adverse reaction develops with Glivec use, treatment must be withheld until the event has resolved.
Danish: Hvis der opstår alvorlige ikke-hæmatologiske bivirkninger ved behandling med Glivec, skal behandlingen seponeres, indtil bivirkningerne er ophørt.
English: Resume treatment with Glivec at 600 mg. 3.
Danish: Genoptag behandling med Glivec 600 mg. 3.
English: Haematological response CHR rate n (%)
Danish: Hæmatologisk respons CHR rate n (%)
English: Paediatric patients: A total of 26 paediatric patients of age < 18 years with either chronic phase CML (n=11) or CML in blast crisis or Ph+ acute leukaemias (n=15) were enrolled in a dose-escalation phase I trial.
Danish: Pædiatriske patienter: Ialt 26 pædiatriske patienter i alderen <18 år med enten CML i kronisk fase (n=11) eller CML i blastkrise eller Ph+ akut leukæmi (n=15) blev inkluderet i en fase I undersøgelse med dosis-eskalering.
English: Talk to your doctor before taking Glivec: - if you have or have ever had a liver, kidney or heart problem.
Danish: Advarsler og forsigtighedsregler Kontakt lægen, før du tager Glivec: - hvis du har eller har haft lever-, nyre- eller hjerteproblemer.
English: A slight to moderate reduction in spermatogenesis was also observed in the dog at oral doses  30 mg/kg.
Danish: Der sås også en let til moderat reduktion i spermatogenesen hos hunde ved orale doser >30 mg/kg.
English: Maximal plasma concentrations of imatinib in patients are 2-4 mol/l, consequently an inhibition of CYP2D6 and/or CYP3A4/5-mediated metabolism of co-administered drugs is possible.
Danish: Maksimale plasmakoncentrationer af imatinib er hos patienter 2-4 mol/l, og hæmning af CYP2D6 og/eller CYP3A4/5-medieret metabolisme af samtidigt administrerede lægemidler er derfor mulig.
English: Glivec inhibits the growth of these cells in a certain subtype of these diseases.
Danish: Glivec hæmmer væksten af disse celler i en vis undergruppe af disse sygdomme.
English: Using this approach, the estimated cumulative response rates for first-line treatment with Glivec improved from 12 months of therapy to 84 months of therapy as follows: CHR from 96.4% to 98.4% and CCyR from 69.5% to 87.2%, respectively.
Danish: Ved brug af denne metode øgedes den estimerede kumulative responsfrekvens for førstevalgsbehandling med Glivec fra 12 måneders behandling til 84 måneders behandling som følgende: CHR fra 96,4% til 98,4% og CCyR fra 69,5% til 87,2%).
English: This will help protect you from stomach problems when taking
Danish: Dette vil hjælpe med at beskytte dig mod maveproblemer,
English: Glivec was administered intermittently in cohorts 1-5, with increasing duration and earlier start of Glivec from cohort to cohort; cohort 1 receiving the lowest intensitiy and cohort 5 receiving the highest intensity of Glivec (longest duration in days with continuous daily Glivec dosing during the first chemotherapy treatment courses).
Danish: Glivec blev administreret periodisk i kohorte 1-5 med stigende varighed og tidligere start med Glivec fra kohorte til kohorte; kohorte 1 fik den mindst intensive Glivecbehandling og kohorte 5 den mest intensive (længste varighed i dage med kontinuerlig, daglig Glivecdosering i de første kemobehandlingsforløb).
English: • the treatment of adult patients with unresectable dermatofibrosarcoma protuberans (DFSP) and adult patients with recurrent and/or metastatic DFSP who are not eligible for surgery.
Danish: • behandling af voksne patienter med inoperabel dermatofibrosarkom protuberans (DFSP) og voksne patienter med residiverende og/eller metastaserende DFSP som ikke er tilgængelig for kirurgi.
English: In this retrospective analysis, the superiority of Glivec over IFN+Ara-C in overall survival was demonstrated (p<0.001); within 42 months, 47 (8.5%) Glivec patients and 63 (19.4%) IFN+Ara-C patients had died.
Danish: I denne retrospektive analyse af total overlevelse blev Glivecs overlegenhed vist i forhold til IFN+AraC (p<0,001); inden for 42 måneder var 47 (8,5%) Glivec-patienter og 63 (19,4%) IFN+Ara-Cpatienter døde.
English: Pretreatment with multiple doses of rifampicin 600 mg followed by a single 400 mg dose of Glivec resulted in decrease in Cmax and AUC(0-∞) by at least 54% and 74%, of the respective values without rifampicin treatment.
Danish: Præbehandling med gentagne doser af rifampicin 600 mg efterfulgt af enkeltdosis Glivec 400 mg resulterede i fald i Cmax og AUC(0-∞) på mindst 54% og 74% af værdierne uden rifampicinbehandling.
English: Stop Glivec until ANC  1.5 x 10
Danish: Stop Glivec indtil ANC 1,5 x 10
English: The primary efficacy variable of the study was the rate of major cytogenetic response (complete plus partial response, 0 to 35% Ph+ metaphases in the bone marrow).
Danish: Undersøgelsens primære effektvariable var graden af det cytogenetiske hovedrespons (fuldstændigt plus partielt respons, 0-35% Ph metafaser i knoglemarven).
English: Chronic phase, newly diagnosed: This phase III study in adult patients compared treatment with either single-agent Glivec or a combination of interferon-alpha (IFN) plus cytarabine (Ara-C).
Danish: Kronisk fase, nydiagnosticeret: Denne fase III undersøgelse hos voksne patienter sammenlignede enkeltstof-behandling med Glivec med behandling med en kombination af interferon-alfa (IFN) og cytarabin (Ara-C).
English: Due to the possible occurrence of tumour lysis syndrome (TLS), correction of clinically significant dehydration and treatment of high uric acid levels are recommended prior to initiation of Glivec (see section 4.8).
Danish: På grund af den mulige forekomst af tumorlysesyndrom (TLS) anbefales korrektion af klinisk signifikant dehydrering og behandling af forhøjede urinsyreniveauer før påbegyndelse af behandling med Glivec (se pkt.
English: BCR-ABL tyrosine kinase inhibitors (TKIs) have been associated with thrombotic microangiopathy (TMA), including individual case reports for Glivec (see section 4.8).
Danish: BCR-ABL-tyrosinkinasehæmmere (TKI'er) er blevet associeret med trombotisk mikroangiopati (TMA), herunder enkeltstående rapporter for Glivec (se pkt.
English: The estimated rate of progression-free survival at 84 months was 81.2% in the Glivec arm and 60.6% in the control arm (p<0.001).
Danish: Den estimerede progressionsfri overlevelse efter 84 måneder var 81,2% i Glivec-armen og 60,6% i kontrolarmen (p<0,001).
English: 9/l) being between 4 and 6 times higher in blast crisis and accelerated phase (59-64% and 44-63% for neutropenia and thrombocytopenia, respectively) as compared to newly diagnosed patients in chronic phase CML (16.7% neutropenia and 8.9% thrombocytopenia).
Danish: 9/l) var 4-6 gange højere ved blastkrise og accelereret fase (59-64% og 44-63% for henholdsvis neutropeni og trombopeni) end ved sammenligning med nydiagnosticerede patienter med kronisk fase CML (16,7% neutropeni og 8,9% trombocytopeni).
English: If any of these apply to you, tell your doctor before taking Glivec.
Danish: Hvis noget af det ovenstående gælder for dig, skal du fortælle din læge det, før du tager Glivec.
English: In two clinical studies (study B2222 and an intergroup study S0033) the daily dose of Glivec was escalated to 800 mg in patients progressing at the lower daily doses of 400 mg or 600 mg.
Danish: I to kliniske undersøgelser (studie B2222 og et mellemgruppe studie S0033) blev den daglige dosis optrappet til 800 mg hos patienter, hvis sygdom fremskrider ved de lavere daglige doser på 400 mg eller 600 mg.
English: What you need to know before you take Glivec
Danish: Det skal du vide, før du begynder at tage Glivec
English: There is very limited experience in children with MDS/MPD, DFSP, GIST and HES/CEL.
Danish: Der er meget begrænset erfaring hos børn med MDS/MPD, DFSP, GIST og HES/CEL.
English: Carriers of HBV who require treatment with Glivec should be closely monitored for signs and symptoms of active HBV infection throughout therapy and for several months following termination of therapy (see section 4.8).
Danish: Bærere af HBV, hvor behandling med Glivec er nødvendig, skal overvåges tæt for tegn og symptomer på aktiv HBV-infektion i hele behandlingsperioden og i flere måneder efter behandlingsophør (se pkt.
English: Very dark yellow to brownish-orange, ovaloid, biconvex film-coated tablet with bevelled edges, debossed with “glivec” on one side.
Danish: Meget mørk gul til brunlig-orange oval, bikonveks, filmovertrukken tablet med skrå kanter, præget med ”glivec” på den ene side.
English: Rates of complete haematological response, major cytogenetic response and complete cytogenetic response on first-line treatment were estimated using the Kaplan-Meier approach, for which nonresponses were censored at the date of last examination.
Danish: Frekvensen for fuldstændig hæmatologisk respons, cytogenetisk respons og fuldstændig cytogenetisk respons for førstevalgsbehandling blev estimeret ved brug af Kaplan-Meier-metoden, hvor patienter, der ikke responderede, blev sorteret fra ved datoen for sidste undersøgelse.
English: If this applies to you, tell your doctor without taking Glivec.
Danish: Hvis dette gælder for dig, skal du fortælle din læge det, før du tager Glivec.
English: (24 h), day 4; DEX 40 mg/day on days 1-4 and 11-14, alternated with MTX 1 g/m i.v.
Danish: (24 timer), dag 4; DEX 40 mg/dag på dag 1-4 og 11-14, supplerende med MTX 1 g/m i.v.
English: This study included 7 patients with MDS/MPD who were treated with Glivec 400 mg daily.
Danish: I dette studie indgik 7 patienter med MDS/MPD, som blev behandlet med 400 mg Glivec daglig.
English: Imatinib in combination with chemotherapy induction (see Table 4) resulted in a complete haematological response rate of 93% (147 out of 158 evaluable patients) and in a major cytogenetic response rate of 90% (19 out of 21 evaluable patients).
Danish: Imatinib givet i kombination med kemoterapi-induktion (se Tabel 4) resulterede i en komplet hæmatologisk responsrate på 93% (147 ud af 158 evaluerbare patienter), og i en væsentlig cytogenetisk responsrate på 90% (19 ud af 21 evaluerbare patienter).
English: Pregnancy, breast-feeding and fertility - If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby,
Danish: Graviditet, amning og frugtbarhed - Hvis du er gravid eller ammer, har mistanke om, at du er gravid, eller planlægger at blive gravid, skal du spørge din læge til råds, før du tager dette lægemiddel.
English: Very dark yellow to brownish-orange film-coated tablet, round with “NVR” on one side and “SA” and score on the other side.
Danish: Meget mørk gul til brunlig-orange filmovertrukken tablet, rund med ”NVR” på den ene side og ”SA” samt delekærv på den anden side.
English: 9/l, myelocyte+metamyelocyte < 5% in blood, no blasts and promyelocytes in blood, basophils < 20%, no extramedullary involvement] and in studies 0102 and 0109 [ANC  1.5 x 10
Danish: 9/l, myelocyt + metamyelocyt <5% i blodet, ingen blaster eller promyelocytter i blodet, basophiler <20%, ingen ekstramedullær involvering] og i undersøgelse 0102 and 0109 [ANC 1,5 x 10
English: 6-MP 60 mg/m oral, days 26-46
Danish: 6-MP 60 mg/m oral, dag 26-46
English: These reactions can usually be managed by withholding Glivec temporarily and with diuretics and other appropriate supportive care measures.
Danish: Disse tilfælde blev sædvanligvis behandlet ved midlertidigt at tilbageholde behandling med Glivec, og behandle med diuretika og andre relevante, understøttende tiltag.
English: Continuous daily exposure to Glivec early in the course of treatment in combination with chemotherapy in cohort 5patients (n=50) improved the 4-year event-free survival (EFS) compared to historical controls (n=120), who received standard chemotherapy without Glivec (69.6% vs. 31.6%, respectively).
Danish: Kontinuerlig daglig eksponering for Glivec tidligt i behandlingsforløbet i kombination med kemoterapi hos kohorte 5-patienter (n=50) forbedrede den 4årige hændelsesfri overlevelse (EFS) sammenlignet med en historisk kontrolgruppe (n=120), der fik standard-kemoterapi uden Glivec (hhv. 69,6% vs. 31,6%).
English: EU/1/01/198/007 20 tablets (PVC/alu blisters) EU/1/01/198/008 60 tablets (PVC/alu blisters) EU/1/01/198/011 120 tablets (PVC/alu blisters) EU/1/01/198/012 180 tablets (PVC/alu blisters) EU/1/01/198/014 60 tablets (PVDC/alu blisters) EU/1/01/198/015 120 tablets (PVDC/alu blisters) EU/1/01/198/016 180 tablets (PVDC/alu blisters)
Danish: EU/1/01/198/007 20 tabletter (PVC/alu blister) EU/1/01/198/008 60 tabletter (PVC/alu blister) EU/1/01/198/011 120 tabletter (PVC/alu blister) EU/1/01/198/012 180 tabletter (PVC/alu blister) EU/1/01/198/014 60 tabletter (PVDC/alu blister) EU/1/01/198/015 120 tabletter (PVDC/alu blister) EU/1/01/198/016 180 tabletter (PVDC/alu blister)
English: For doses of 400 mg and above (see dosage recommendation below) a 400 mg tablet (not divisible) is available.
Danish: Til doser på 400 mg og derover (se anbefalede doser nedenfor) er en 400 mg tablet (ikke delelig) tilgængelig.
English: Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system.
Danish: Læger og sundhedspersonale anmodes om at indberette alle formodede bivirkninger via det nationale rapporteringssystem anført i Appendiks V.
English: Glivec is also a treatment for adults for:
Danish: Glivec anvendes også til behandling af voksne med:
English: This inhibition has not been observed in vivo after the administration of Glivec 400 mg and paracetamol 1000 mg. Higher doses of Glivec and paracetamol have not been studied.
Danish: Denne hæmning er ikke observeret in vivo efter administrationen af 400 mg Glivec og 1 g paracetamol.
English: In vitro Glivec inhibits the cytochrome P450 isoenzyme CYP2D6 activity at concentrations similar to those that affect CYP3A4 activity.
Danish: In vitro hæmmer Glivec CYP2D6-aktiviteten ved koncentrationer svarende til dem, der påvirker CYP3A4-aktivitet.
English: Use in adults Your doctor will tell you exactly how many tablets of Glivec to take.
Danish: Brug til voksne Din læge vil fortælle dig, præcis hvor mange Glivec-tabletter, du skal tage.
English: A second multicentre, open label phase III study (SSG XVIII/AIO) compared 400 mg/day Glivec 12 months treatment vs. 36 months treatment in patients after surgical resection of GIST and one of the following: tumour diameter > 5 cm and mitotic count > 5/50 high power fields (HPF); or tumour diameter > 10 cm and any mitotic count or tumour of any size with mitotic count > 10/50 HPF or tumours ruptured into the peritoneal cavity.
Danish: Et andet multicenter, åbent fase-III-studie (SSG XVIII/AIO) sammenlignede 12 måneders behandling med Glivec 400 mg/dag vs. 36 måneders behandling hos patienter efter kirurgisk resektion af GIST og en af følgende: tumordiameter >5 cm og antal mitoser >5/50 HPF (high power fields); eller tumordiameter >10 cm og uanset antal mitoser; eller tumor af enhver størrelse med antal mitoser >10/50 HPF; eller tumorer, der er bristet i bughulen.
English: The primary efficacy variable was the rate of haematological response, reported as either complete haematological response, no evidence of leukaemia (i.e. clearance of blasts from the marrow and the blood, but without a full peripheral blood recovery as for complete responses), or return to chronic phase CML.
Danish: Den primære effektvariable var graden af hæmatologisk hovedrespons, rapporteret enten som fuldstændigt hæmatologisk respons, intet tegn på leukæmi (f.eks. clearance af blaster fra knoglemarv og blod, men uden fuldstændig restitution i perifert blod som ved fuldstændigt respons) eller remission til CML i kronisk fase.
English: In this study, 14 patients with HES/CEL were treated with 100 mg to 1,000 mg of Glivec daily.
Danish: I dette studie blev 14 patienter med HES/CEL behandlet med 100 mg1.000 mg Glivec daglig.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Glivec in all subsets of the paediatric population in Philadelphia chromosome (bcr-abl translocation)positive chronic myeloid leukaemia (see section 4.2 for information on paediatric use).
Danish: Det Europæiske Lægemiddelagentur har dispenseret fra kravet om at fremlægge resultaterne af studier med Glivec i alle undergrupper af den pædiatriske population med Philadelphia-kromosom (bcr-abl translokation)-positiv kronisk myeloid leukæmi (se pkt.
English: 9/l, myelocyte+metamyelocyte < 5% in blood, no blasts and promyelocytes in blood, basophils < 20%, no extramedullary involvement Cytogenetic response criteria: complete (0% Ph+ metaphases), partial (1-35%), minor (36-65%) or minimal (66-95%).
Danish: 9/l, myelocytter+metamyelocytter <5% i blod, ingen blaster og promyelocytter i blod, basofile <20%, ingen ekstramedullær påvirkning Cytogenetiske responskriterier: fuldstændig (0% Ph+ metafaser), delvis (1-35%), mindre (3665%) eller minimal (66-95%).
English: Intermediate 25.7 4/75 vs. 6/78
Danish: Mellem 25,7 4/75 vs. 6/78