FrancophonIA/ELRC3.0 huggingface dataset:
English: • have under-active thyroid gland which can cause tiredness or weight gain
Danish: • har en underaktiv skjoldbruskkirtel, hvilket kan forårsage træthed eller vægtforøgelse
English: Zubsolv should be used cautiously when co-administered with:
Danish: Zubsolv bør anvendes med forsigtighed ved samtidig administration af:
English: Zubsolv contains the active substances buprenorphine and naloxone.
Danish: Zubsolv indeholder de aktiver stoffer buprenorphin og naloxon.
English: This medicine can cause drowsiness, particularly when taken together with alcohol or other central nervous system depressants (such as tranquilisers, sedatives or hypnotics).
Danish: Dette lægemiddel kan forårsage døsighed, især når det tages sammen med alkohol eller andre midler som hæmmer centralnervesystemet (såsom beroligende midler, sedativa eller hypnotika).
English: Starting treatment
Danish: Indledende behandling
English: Both active substances of Zubsolv, buprenorphine and naloxone, are extensively metabolized in the liver, and the plasma levels were found to be higher for both buprenorphine and naloxone in patients with moderate and severe hepatic impairment.
Danish: Begge aktive indholdsstoffer i Zubsolv, buprenorphin og naloxon, metaboliseres i udbredt grad i leveren, og der blev fundet højere plasmaniveauer af både buprenorphin og naloxon hos patienter med moderat eller alvorligt nedsat leverfunktion.
English: In patients with severe hepatic insufficiency the use of buprenorphine/naloxone is contraindicated (see section 4.3).
Danish: Hos patienter med alvorlig leverinsufficiens er brugen af buprenorphin/naloxon kontraindiceret (se pkt.
English: • Do not consume any food or drink until the tablets have completely dissolved.
Danish: • Lad være med at spise eller drikke noget, før resoribletterne er helt opløste.
English: Leukocytosis Leukopenia Lymphadenopathy Thrombocytopenia
Danish: Leukocytose Leukopeni Lymfadenopati Trombocytopeni
English: “2.9” on one side
Danish: ”2.9” på den ene side
English: 14.0-fold increase
Danish: 14,0-folds stigning
English: Pack-size of 7 (1 x 7) tablets.
Danish: Pakningsstørrelse: 7 (1 x 7) resoribletter.
English: As buprenorphine/naloxone pharmacokinetics may be altered in patients with hepatic impairment, lower initial doses and careful dose titration in patients with mild to moderate hepatic impairment are recommended (see section 5.2).
Danish: Da buprenorphin/naloxons farmakokinetiske egenskaber kan være ændret hos patienter med nedsat leverfunktion, anbefales en lavere initialdosis og omhyggelig dosistitrering hos patienter med let til moderat nedsat leverfunktion (se pkt.
English: • rapid or slow heartbeat, myocardial infarction (heart attack), palpitations, chest tightness
Danish: • hurtig eller langsom puls, myokardieinfarkt (hjerteanfald), hjertebanken, trykken for brystet
English: Urine abnormality Albuminuria Dysuria
Danish: Urin abnormalitet Albuminuri Dysuri
English: Metabolites of buprenorphine accumulate in patients with renal failure.
Danish: Buprenorphins metabolitter akkumuleres hos patienter med nyresvigt.
English: Common side effects (may affect up to 1 in 10 people):
Danish: Almindelige bivirkninger (kan påvirke op til 1 ud af 10 personer):
English: If you forget to take Zubsolv
Danish: Hvis du har glemt at tage Zubsolv
English: 2.9 mg / 0.71 mg 30 months 5.7 mg / 1.4 mg 4 years
Danish: 2,9 mg/0,71 mg 30 måneder 5,7 mg/1,4 mg 4 år
English: • increased tearing (watering eyes) or other tearing disorder
Danish: • øget tåreflåd (øjnene løber i vand) eller på anden måde ændret tåreflåd
English: • Keep the tablets in place under the tongue until they have completely dissolved
Danish: • Lad resoribletterne blive under tungen, indtil de er helt opløst
English: Table 1: Treatment related adverse reactions reported in clinical trials and post-marketing surveillance of buprenorphine/naloxone
Danish: Tabel 1: Behandlingsrelaterede bivirkninger, der blev indberettet fra kliniske studier og via overvågningen efter markedsføring af buprenorphin/naloxon Systemorganklasse Meget almindelig
English: Therefore, patients should be monitored when changing between different buprenorphine containing products as differences in bioavailability (see section 5.2) may be noticeable in some individual cases.
Danish: Derfor bør patienterne overvåges, når der skiftes mellem forskellige buprenorphinindeholdende produkter, da forskelle i biotilgængelighed (se pkt.
English: Baseline liver function tests and documentation of viral hepatitis status is recommended prior to commencing therapy.
Danish: Det anbefales at tage baseline leverfunktionsprøver og dokumentation for viral hepatitisstatus, inden behandlingen indledes.
English: CYP 3A inhibitors
Danish: CYP 3A-hæmmere
English: Abrupt discontinuation of treatment is not recommended as it may result in withdrawal syndrome with delayed onset.
Danish: Pludselig afbrydelse af behandlingen frarådes, da det kan forårsage forsinkede abstinenssymptomer.
English: blood in urine, kidney stone
Danish: blod i urinen, nyresten
English: Dosage adjustment and maintenance therapy
Danish: Dosisjustering og vedligeholdelsesbehandling
English: Since both buprenorphine and naloxone are extensively metabolized in liver, plasma levels were found to be higher for both buprenorphine and naloxone in patients with moderate and severe hepatic impairment after single-dose administration.
Danish: Da både buprenorphin og naloxon metaboliseres i stort omfang i leveren, blev plasmaniveauerne fundet at være højere for både buprenorphin og naloxon hos patienter med moderat eller alvorligt nedsat leverfunktion efter administration af en enkeltdosis.
English: • amnesia (memory disturbance), convulsion (fits), speech disorder, tremor
Danish: • amnesi (hukommelsesforstyrrelse), kramper (anfald), taleforstyrrelser, skælven
English: Zubsolv tablet strength
Danish: Zubsolv resoribletstyrke
English: “5.7” on one side
Danish: ”5.7” på den ene side
English: Uncommon side effects (may affect up to 1 in 100 people):
Danish: Ikke almindelige bivirkninger (kan påvirke op til 1 ud af 100 personer):
English: Sublingual tablet
Danish: Sublingual resoriblet
English: An emergency unit should be contacted immediately in case of accidental ingestion or suspicion of ingestion.
Danish: Skadestuen skal kontaktes øjeblikkelig i tilfælde af utilsigtet indtagelse eller ved mistanke herom.
English: Other medicines and Zubsolv
Danish: Brug af anden medicin sammen med Zubsolv
English: • the concomitant use of monoamine oxidase inhibitors (MAOI) might produce exaggeration of the effects of opioids, based on experience with morphine
Danish: • Samtidig behandling med monoaminooxidase-hæmmere (MAO-hæmmere) kan muligvis forårsage øget virkning af opioiderne, baseret på erfaring med morfin
English: • abnormal blood tests swollen, glands (lymph nodes)
Danish: • unormale blodprøver, hævede kirtler (lymfeknuder)
English: Urinary tract infection Vaginal infection
Danish: Urinvejsinfektion Vaginal infektion
English: An additional Zubsolv 1.4 mg / 0.36 mg or 2.9 mg / 0.71 mg may be administered on day one depending on the individual patient's requirement.
Danish: Yderligere en Zubsolv 1,4 mg/0,36 mg eller 2,9 mg/0,71 mg kan administreres på Dag 1, afhængigt af den enkelte patients behov.
English: Naloxone
Danish: Naloxon
English: Opioid agonist ceiling effects were observed during clinical pharmacology studies in opioid-dependent patients.
Danish: Der blev observeret et loft for den opioidagonistisk effekt hos opioidafhængige personer i kliniske farmakologiske studier.
English: Dietary administration of buprenorphine in the rat at dose levels of 500 ppm or greater produced a reduction in fertility demonstrated by reduced female conception rates.
Danish: Buprenorphin i foderet til rotter i doser på 500 ppm eller højere forårsagede reduceret fertilitet i form af nedsat befrugtningsfrekvens hos hunrotter.
English: • other central nervous system depressants, other opioid derivatives (e.g. methadone, analgesics and antitussives), certain antidepressants, sedative H1-receptor antagonists, barbiturates, anxiolytics other than benzodiazepines, neuroleptics, clonidine and related substances: these combinations increase central nervous system depression.
Danish: • andre lægemidler, der hæmmer centralnervesystemet, andre opioidderivater (f.eks. metadon, analgetika og antitussiva), visse antidepressiva, sederende H1-receptorantagonister, barbiturater, andre anxiolytika end benzodiazepiner, neuroleptika, klonidin og beslægtede stoffer.
English: Induction
Danish: Induktion
English: A number of cases of death due to respiratory depression have been reported, particularly when buprenorphine was used in combination with benzodiazepines (see section 4.5) or when buprenorphine was not used according to prescribing information.
Danish: Der er modtaget indberetning om en række dødsfald forårsaget af respirationsdepression, særligt når buprenorphin blev anvendt samtidigt med benzodiazepiner (se pkt.
English: In patients with marked drug dependence, initial administration of buprenorphine can produce a drug withdrawal syndrome similar to that associated with naloxone (see sections 4.2 and 4.4).
Danish: Hos patienter med udpræget stofafhængighed kan indledende administration af buprenorphin fremkalde et abstinenssyndrom svarende til det, der er forbundet med naloxon (se pkt.
English: Moderate Hepatic Impairment (Child-Pugh Class B) (n=8)
Danish: Moderat nedsat leverfunktion (Child-Pugh klasse B) (n=8)
English: Orexo AB Virdings allé 32A Uppsala 751 05 Sweden
Danish: Orexo AB Virdings allé 32A Uppsala
English: Decreased appetite Hyperglycaemia Hyperlipidaemia Hypoglycaemia
Danish: Nedsat appetit Hyperglykæmi Hyperlipidæmi Hypoglykæmi
English: • acne, hair loss, dry or scaling skin, skin nodule
Danish: • akne, hårtab, tør eller afskallende hud, buler i huden
English: What you need to know before you take Zubsolv Do not take Zubsolv if you:
Danish: Det skal du vide, før du begynder at tage Zubsolv Tag ikke Zubsolv, hvis du:
English: All strengths will be available as packs of 7, 28, and 30 tablets presented in aluminium blisters.
Danish: Alle styrker fås i pakker på 7, 28, og 30 resoribletter i blisterpakker af folie.
English: Buprenorphine, when taken orally, undergoes first-pass metabolism with N-dealkylation and glucuroconjugation in the small intestine and the liver.
Danish: Når det indtages oralt gennemgår buprenorphin first-pass metabolisme med N-dealkylering og glukuronidkonjugering i tyndtarmen og leveren.
English: If naloxone is used, the long duration of action of buprenorphine should be taken into consideration when determining the length of treatment and medical surveillance needed to reverse the effects of an overdose.
Danish: Hvis naloxon anvendes til behandling af en overdosis, skal der tages højde for den lange virkningsvarighed af buprenorphin, når varigheden af behandling og overvågning fastlægges.
English: No dose modification based on renal function is required but caution is recommended when dosing subjects with severe renal impairment (see section 4.4).
Danish: Det er ikke nødvendigt at foretage dosisjustering baseret på nyrefunktionen, men forsigtighed anbefales ved dosering til personer med alvorligt nedsat nyrefunktion (se pkt.
English: Hepatic encephalopathy Syncope
Danish: Hepatisk encefalopati Synkope
English: 30 mg/day before beginning buprenorphine/naloxone therapy.
Danish: mg/dag, inden behandling med buprenorphin/naloxon påbegyndes.
English: Caution is recommended when dosing patients with severe renal impairment (creatinine clearance <30 ml/min) (see sections 4.2 and 5.2).
Danish: Forsigtighed tilrådes ved dosering for patienter med alvorligt nedsat nyrefunktion (kreatininclearance <30 ml/min) (se pkt.
English: Zubsolv is not interchangeable with other buprenorphine products.
Danish: Zubsolv kan derfor ikke udskiftes med andre buprenorphin produkter.
English: Opioids should be used with caution in patients with myxoedema, hypothyroidism, or adrenal cortical insufficiency (e.g., Addison's disease).
Danish: Opioider bør anvendes med forsigtighed til patienter med myksødem, hypothyroidisme eller binyrebarkinsufficiens (f.eks. Addisons sygdom).
English: White, round tablets, 7 mm in diameter, debossed with “5.7” on one side.
Danish: Hvide, runde resoribletter, 7 mm i diameter, præget med “5.7” på den ene side.
English: Following oral administration, naloxone is barely detectable in plasma; following sublingual administration of buprenorphine/naloxone, plasma naloxone concentrations are low and decline rapidly.
Danish: Efter sublingual administration af buprenorphin/naloxon er plasmakoncentrationerne for naloxon lave og falder hurtigt.
English: Urinary retention
Danish: Urinretention
English: Table 3: Effect of hepatic impairment on pharmacokinetic parameters of buprenorphine and naloxone following administration (change relative to healthy subjects) PK Parameter
Danish: Virkning af nedsat leverfunktion på de farmakokinetiske parametre for buprenorphin og naloxon efter administration (forskel i forhold til raske forsøgspersoner) Farmakokinetisk parameter
English: The first dose of buprenorphine/naloxone should be taken only when signs of withdrawal appear, but not less than 24 hours after the patient last used methadone.
Danish: Den første dosis buprenorphin/naloxon skal først administreres, når der optræder tegn på abstinenser, dog mindst 24 timer efter, at patienten sidst anvendte metadon.
English: Very common Common
Danish: Ikke almindelig
English: If taken together with alcohol or central nervous system depressants, the effect is likely to be more pronounced (see sections 4.4 and 4.5).
Danish: Hvis det indtages sammen med alkohol eller CNS-supprimerende midler, vil virkningen sandsynligvis være mere udtalt (se pkt.
English: Severe Hepatic Impairment (Child-Pugh Class C) (n=8)
Danish: Svært nedsat leverfunktion (Child-Pugh klasse C) (n=8)
English: Buprenorphine/naloxone is contraindicated in patients with severe hepatic impairment (see sections 4.3 and 5.2).
Danish: Buprenorphin/naloxon er kontraindiceret hos patienter med alvorligt nedsat leverfunktion (se pkt.
English: Mouth ulceration Tongue discolouration
Danish: Oral ulcerea Misfarvning af tungen
English: Blood creatinine increased
Danish: Forhøjet blodkreatinin Øgede transaminaser
English: The concomitant use of monoamine oxidase inhibitors (MAOI) might produce an exaggeration of opioid effects, based on experience with morphine (see section 4.5).
Danish: Samtidig behandling med monoaminooxidase-hæmmere (MAO-hæmmere) kan eventuelt forårsage øget virkning af opioider, baseret på erfaring med morfin (se pkt.
English: The first dose of Zubsolv should be taken when signs of withdrawal appear, but not less than 24 hours after you last used methadone
Danish: Den første dosis Zubsolv skal tages, når der ses tegn på abstinenser, dog mindst 24 timer efter, du sidst brugte metadon
English: Medicinal product subject to special and restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Danish: Lægemidlet må kun udleveres efter ordination på en særlig recept udstedt af en begrænset lægegruppe (se bilag I: Produktresumé, pkt.
English: “1.4” on one side
Danish: ”1.4” på den ene side
English: Hypothermia
Danish: Hypotermi
English: Buprenorphine/naloxone may cause drowsiness, particularly when taken together with alcohol or central nervous system depressants (such as tranquilisers, sedatives or hypnotics) (see section 4.5).
Danish: Buprenorphin/naloxon kan forårsage sløvhed, særligt ved samtidig indtagelse af alkohol eller CNSdepressiva (som f.eks. beroligende midler, sedativa eller hypnotika) (se pkt.
English: one tablet of Zubsolv 1.4 mg / 0.36 mg each day, or
Danish: - én Zubsolv resoriblet på 1,4 mg/0,36 mg hver dag, eller
English: When taken during pregnancy, particularly late pregnancy, medicines like Zubsolv may cause drug withdrawal symptoms including problems with breathing in your newborn baby.
Danish: Hvis lægemidler som Zubsolv indtages under graviditet, især sidst i graviditeten, kan det medføre, at barnet fødes med abstinenssymptomer, inklusiv vejrtrækningsproblemer.
English: Mild hepatic Impairment (Child-Pugh Class A) (n=9)
Danish: Let nedsat leverfunktion (Child-Pugh klasse A) (n=9)
English: 0.2-fold decrease
Danish: 0,2-folds fald
English: Asthma Dyspnoea Yawning
Danish: Astma Dyspnø Gaben
English: • increased cough
Danish: • øget hoste
English: An additional tablet of the Zubsolv 1.4 mg / 0.36 mg or 2.9 mg / 0.71 mg may be administered on Day 1 depending on your needs.
Danish: Yderlige én Zubsolv resoriblet på 1,4 mg/0,36 mg eller 2,9 mg/0,71 mg kan gives på dag 1, afhængigt af dit behov.
English: • abnormal liver function, weight loss
Danish: • unormal leverfunktion, vægttab
English: • migraines, dizziness, fainting, increase in muscle tension, tingling, drowsiness
Danish: • migræne, svimmelhed, besvimelse, øget muskelspænding, prikkende fornemmelse, døsighed
English: White, oval tablet, length 6.8 mm and width 4.0 mm
Danish: Hvid, oval resoriblet, længde 6,8 mm og bredde 4,0 mm
English: Do not swallow or consume food or any drink until the tablet is completely dissolved.
Danish: Du må ikke synke eller indtage mad eller drikke, før resoribletten er helt opløst.
English: Stopping treatment suddenly may cause withdrawal symptoms.
Danish: Pludseligt behandlingsophør kan forårsage abstinenser.
English: • asthma, shortness of breath, yawning
Danish: • astma, åndenød, gaben
English: • abnormal dreams, agitation, loss of interest, depersonalisation (not feeling like yourself),
Danish: • unormale drømme, agitation, manglende interesse, depersonalisation (fornemmelse af ikke at være sig selv), lægemiddelafhængighed, overdreven følelse af velvære, følelse af fjendtlighed
English: Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Danish: Overfølsomhed over for de aktive stoffer eller over for ét eller flere af hjælpestofferne anført i pkt.
English: White, triangular tablet, base 7.2 mm and height 6.9 mm
Danish: Hvid, trekantet resoriblet, grundlinje 7,2 mm og højde 6,9 mm
English: 11.3-fold increase
Danish: 11,3-folds stigning
English: Zubsolv 0.7 mg / 0.18 mg sublingual tablets Zubsolv 1.4 mg / 0.36 mg sublingual tablets Zubsolv 2.9 mg / 0.71 mg sublingual tablets Zubsolv 5.7 mg / 1.4 mg sublingual tablets Zubsolv 8.6 mg / 2.1 mg sublingual tablets Zubsolv 11.4 mg / 2.9 mg sublingual tablets
Danish: Zubsolv 0,7 mg/0,18 mg sublinguale resoribletter Zubsolv 1,4 mg/0,36 mg sublinguale resoribletter Zubsolv 2,9 mg/0,71 mg sublinguale resoribletter Zubsolv 5,7 mg/1,4 mg sublinguale resoribletter Zubsolv 8,6 mg/2,1 mg sublinguale resoribletter Zubsolv 11,4 mg/2,9 mg sublinguale resoribletter
English: 0.7 mg / 0.18 mg 2 years
Danish: 0,7 mg/0,18 mg 2 år
English: • weakness, chest pain, chills, fever, feeling of general discomfort, pain, swelling (hands and feet)
Danish: • svaghed, brystsmerter, kulderystelser, feber, følelse af generelt ubehag, smerter, hævelse
English: Opioids may elevate cerebrospinal fluid pressure, which may cause seizures, so opioids should be used with caution in patients with head injury, intracranial lesions, other circumstances where cerebrospinal pressure may be increased, or history of seizure.
Danish: Derfor bør opioider anvendes med forsigtighed til patienter med hovedlæsioner, intrakranielle læsioner, andre forhold, hvor cerebrospinaltrykket kan øges, eller anamnese med krampeanfald.
English: The active substances are buprenorphine and naloxone.
Danish: Aktive stoffer: buprenorphin og naloxon.
English: You can also report side effects directly via the national reporting system listed in Appendix V.By reporting side effects you can help provide more information on the safety of this medicine.
Danish: Hvis du oplever bivirkninger, bør du tale med din læge, sygeplejerske eller apoteket.Dette gælder også mulige bivirkninger, som ikke er medtaget i denne indlægsseddel.Du eller dine pårørende kan også indberette bivirkninger direkte til Lægemiddelstyrelsen via det nationale rapporteringssystem anført i Appendiks V. Ved at indrapportere bivirkninger kan du hjælpe med at fremskaffe mere information om sikkerheden af dette lægemiddel.
English: 8.6 mg / 2.1 mg 3 years
Danish: 8,6 mg/2,1 mg 3 år
English: White, D-shaped tablet, height 7.3 mm and width 5.65 mm
Danish: Hvid, D-formet resoriblet, højde 7,3 mm og bredde 5,65 mm
English: Zubsolv sublingual tablets should be used with caution in patients with moderate hepatic impairment (see sections 4.2 and 5.2).
Danish: Zubsolv sublinguale resoribletter bør anvendes med forsigtighed hos patienter med moderat nedsat leverfunktion (se pkt.
English: Opioids may produce orthostatic hypotension in ambulatory patients.
Danish: Generelle advarsler, der er relevante ved administration af opioider Opioider kan fremkalde ortostatisk hypotension hos ambulante patienter.
English: Contents of the pack and other information What Zubsolv contains
Danish: Pakningsstørrelser og yderligere oplysninger Zubsolv indeholder:
English: • abdominal pain, upset stomach or other stomach discomfort, diarrhoea, flatulence, vomiting
Danish: • mavesmerter, mavebesvær eller andet maveubehag, diarré, luft i maven, opkastning
English: For steps of 1.4-5.7 mg buprenorphine this titration is guided by reassessment of the clinical and psychological status of the patient, and should not exceed a maximum single daily dose of 17.2 mg buprenorphine (e.g. given as 11.4 + 5.7 mg, 2 x 8.6 mg or 3 x 5.7 mg).
Danish: En maksimal daglig dosis på 17,2 mg buprenorphin som enkeltdosis (f.eks. givet som 11,4 + 5,7 mg, 2 x 8,6 mg eller 3 x 5,7 mg) bør ikke overskrides.
English: 11.4 mg / 2.9 mg 3 years
Danish: 11,4 mg/2,9 mg 3 år
English: “.7” on one side
Danish: ”.7” på den ene side
English: White, capsule shaped tablets, length 10.3 mm and width 8.2 mm, debossed with “11.4” on one side.
Danish: Hvide, kapselformede resoribletter, længde 10,3 mm og bredde 8,2 mm, præget med “11.4” på den ene side.
English: 1.4 mg / 0.36 mg 4 years
Danish: 1,4 mg/0,36 mg 4 år
English: 2.8-fold increase
Danish: 2,8-folds stigning
English: • CYP3A4 inhibitors: an interaction study of buprenorphine with ketoconazole (a potent inhibitor of CYP3A4) resulted in increased Cmax and AUC (area under the curve) of buprenorphine (approximately 50 % and 70 % respectively) and, to a lesser extent, of norbuprenorphine Patients receiving Zubsolv should be closely monitored, and may require dose-reduction if combined with potent CYP3A4 inhibitors (e.g. protease inhibitors like ritonavir, nelfinavir or indinavir, azole antifungals such as ketoconazole, itraconazole or macrolide antibiotics)
Danish: • CYP3A4-hæmmere: En interaktionsundersøgelse med buprenorphin med ketoconazol (en potent CYP3A4-hæmmer) resulterede i øget Cmax og AUC (areal under kurven) af buprenorphin (henholdsvis ca. 50 % og 70 %) og i mindre grad af norbuprenorphin.
English: Alopecia Dermatitis exfoliative Dry skin Skin mass
Danish: Eksfoliativ dermatitis Tør hud
English: White, capsule shaped tablet, length 10.3 mm and width 8.2 mm
Danish: Hvid, kapselformet resoriblet, længde 10,3 mm og bredde 8,2 mm
English: Hepatitis and hepatic events
Danish: Hepatitis og leverlidelser
English: To avoid precipitating withdrawal, induction with buprenorphine/naloxone should be undertaken when objective signs of withdrawal are evident (see section 4.2).
Danish: For at undgå at fremprovokere abstinenssymptomer bør administration med buprenorphin/naloxon først indledes, når der ses objektive tegn på abstinenser (se pkt.
English: Buprenorphine may precipitate symptoms of withdrawal in patients dependent upon methadone.
Danish: Buprenorphin kan udløse abstinenssymptomer hos metadonafhængige patienter.
English: Amblyopia Lacrimal disorder
Danish: Amblyopi Ændret tåreflåd
English: White, D-shaped tablets, height 7.3 mm and width 5.65 mm, debossed with “2.9” on one side.
Danish: Hvide, D-formede resoribletter, højde 7,3 mm og bredde 5,65 mm, præget med “2.9” på den ene side.
English: • have problems with the biliary tract (e.g. gall bladder, bile duct)
Danish: • har problemer med galdevejen (f.eks. galdeblæren, galdegangen)