FrancophonIA/ELRC3.0 huggingface dataset:
English: • Feeling sick (nausea), with loss of appetite, dark-coloured urine, yellow skin or eyes (signs of liver problems).
Danish: • Have kvalme med tab af appetitten, mørk urin, gul hud eller øjne (tegn på leverproblemer).
English: However, the occurrence of cytopenias was also clearly dependent on the stage of the disease, the frequency of grade 3 or 4 neutropenias (ANC < 1.0 x 109/l) and thrombocytopenias (platelet count < 50 x 109/l) being between 4 and 6 times higher in blast crisis and accelerated phase (59-64% and 44-63% for neutropenia and thrombocytopenia, respectively) as compared to newly diagnosed patients in chronic phase CML (16.7% neutropenia and 8.9% thrombocytopenia).
Danish: Incidensen af cytopeni hang imidlertid også tydeligt sammen med sygdomsstadiet, idet hyppighed af 3. eller 4. grads neutropeni (ANC <1,0 x 109/l) og trombocytopeni (trombocyttal <50 x 109/l) var 4-6 gange højere ved blastkrise og accelereret fase (59-64% og 44-63% for henholdsvis neutropeni og trombopeni) end ved sammenligning med nydiagnosticerede patienter med kronisk fase CML (16,7% neutropeni og 8,9% trombocytopeni).
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER
Danish: NAME OF THE MARKETING AUTHORISATION HOLDER
English: MTX 15 mg intrathecal, day 1; Methylprednisolone 40 mg intrathecal, day 1
Danish: 15 mg intrathecal, dag 1; methylprednisolon 40 mg intrathecal, dag 1
English: - if you experience bruising, bleeding, fever, fatigue and confusion when taking Imatinib Teva,
Danish: - hvis du får blå mærker, blødninger, feber, træthed og oplever forvirring, mens du tager Imatinib Teva, skal du kontakte din læge.
English: Total bilirubin: > 3-10 ULN
Danish: Total bilirubin: > 3-10 ULN AST: alt
English: Imatinib is mainly metabolised through the liver.
Danish: Imatinib metaboliseres primært i leveren.
English: Accelerated phase is defined by the presence of any of the following: blasts ≥ 15% but < 30% in blood or bone marrow, blasts plus promyelocytes ≥ 30% in blood or bone marrow (providing < 30% blasts), peripheral blood basophils ≥ 20%, platelets < 100 x 109/l unrelated to therapy.
Danish: Accelereret fase defineres som tilstedeværelse af én eller flere af følgende: blaster ≥15%, men <30% i blod eller knoglemarv, blaster plus promyelocytter ≥30% i blod eller knoglemarv (hvilket giver <30% blaster), perifere blodbasofiltal ≥20%, trombocyttal <100 x 109/l uafhængigt af behandlingen.
English: VCR 1.3 g/m2 i.v., day 1; Prednisolone 60 mg/m2 oral, days 1-5
Danish: VCR 1,3 g/m2 i.v., dag 1; prednisolon 60 mg/m2 oral, dag 1-5
English: - Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph-positive ALL).
Danish: - Philadelphia kromosom positiv akut lymfoblast leukæmi (Ph-positiv ALL).
English: If this applies to you, tell your doctor without taking Imatinib Teva.
Danish: Hvis dette gælder for dig, skal du fortælle din læge det, før du tager Imatinib Teva.
English: Resume treatment with imatinib at 600 mg.
Danish: Genoptag behandling med Imatinib Teva 600 mg.
English: Dose increases from 340 mg/m2 daily to 570 mg/m2 daily (not to exceed the total dose of 800 mg) may be considered in children in the absence of severe adverse drug reaction and severe non-leukaemia-related neutropenia or thrombocytopenia in the following circumstances: disease progression (at any time); failure to achieve a satisfactory haematological response after at least 3 months of treatment; failure to achieve a cytogenetic response after 12 months of treatment; or loss of a previously achieved haematological and/or cytogenetic response.
Danish: Dosisøgning fra 340 mg/m2 daglig til 570 mg/m2 daglig (uden at overstige total dosis på 800 mg) kan overvejes hos børn ved fravær af alvorlige bivirkninger og svær ikke-leukæmirelateret neutropeni eller trombocytopeni ved følgende omstændigheder: sygdomsprogression (på ethvert tidspunkt); hvis der ikke er opnået tilfredsstillende hæmatologisk respons efter mindst 3 måneders behandling; hvis der ikke er opnået cytogenetisk respons efter 12 måneders behandling; eller ved tab af tidligere opnået hæmatologisk og/eller cytogenetisk respons.
English: Other medicines and Imatinib Teva
Danish: Brug af anden medicin sammen med Imatinib Teva
English: Nausea, diarrhoea, vomiting, dyspepsia, abdominal pain6
Danish: Kvalme, diarré, opkast, dyspepsi, abdominalsmerter 6
English: • Muscle cramps or joint, muscle or bone pain, during treatment with Imatinib Teva or after you have stopped taking Imatinib Teva.
Danish: • Muskelkramper eller led-, muskel- eller knoglesmerter mens du er i behandling med Imatinib
English: If any of these apply to you, tell your doctor before taking Imatinib Teva
Danish: Hvis noget af det ovenstående gælder for dig, skal du fortælle din læge det, før du tager Imatinib Teva.
English: For patients unable to swallow the film-coated tablets, the tablets may be dispersed in a glass of still water or apple juice.
Danish: Patienter, der ikke er i stand til at synke de filmovertrukne tabletter, kan dispergere tabletterne i et glas med almindeligt vand eller æblejuice.
English: • Rash, red skin with blisters on the lips, eyes, skin or mouth, peeling skin, fever, raised red or purple skin patches, itching, burning sensation, pustular eruption (signs of skin problems).
Danish: • Udslæt, rød hud med små blærer på læber, øjne, hud eller mund, afskallet hud, feber, hævede røde eller lilla hudområder, kløe, brændende fornemmelse, pustuløst udslæt (tegn på hudproblemer).
English: Table 3 Response in adult CML study
Danish: Tabel 3 Respons hos voksne CML-patienter
English: Dose increases from 400 mg to 600 mg or 800 mg in patients with chronic phase disease, or from 600 mg to a maximum of 800 mg (given as 400 mg twice daily) in patients with accelerated phase or blast crisis may be considered in the absence of severe adverse drug reaction and severe non-leukaemia-related neutropenia or thrombocytopenia in the following circumstances: disease progression (at any time); failure to achieve a satisfactory haematological response after at least 3 months of treatment; failure to achieve a cytogenetic response after 12 months of treatment; or loss of a previously achieved haematological and/or cytogenetic response.
Danish: Dosisøgninger fra 400 mg til 600 mg eller 800 mg til patienter med CML i kronisk fase, eller fra 600 mg til maksimalt 800 mg (givet som 400 mg 2 gange daglig) til patienter i accelereret fase eller i blastkrise kan, hvis der ikke opstår svære bivirkninger og svær ikke-leukæmirelateret neutropeni eller trombocytopeni, overvejes i følgende tilfælde: Sygdomsprogression (til enhver tid), udeblivende tilfredsstillende hæmatologisk respons efter mindst 3 måneders behandling, udeblivende opnåelse af cytogenetisk respons efter 12 måneders behandling, samt hvis tidligere hæmatologisk og/eller cytogenetisk respons ikke genopnås.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/12/808/021-040
Danish: EU/1/12/808/021-040
English: • Adult patients with relapsed or refractory Ph+ ALL as monotherapy.
Danish: • Voksne patienter med Ph+ ALL med tilbagefald eller refraktær sygdom som monoterapi.
English: Relapsed/refractory Ph+ ALL
Danish: Recidiverendet/refraktær Ph+ ALL
English: Newly diagnosed Ph+ ALL
Danish: Nydiagnostiseret Ph+ ALL
English: If you are unable to swallow the tablets, you can dissolve them in a glass of still water or apple juice:
Danish: Hvis du ikke kan synke tabletterne, kan du opløse dem i et glas almindeligt vand eller æblejuice:
English: Imatinib is also an inhibitor of the receptor tyrosine kinases for platelet-derived growth factor (PDGF), PDGF-R, and inhibits PDGF- mediated cellular events.
Danish: Imatinib hæmmer også receptortyrosinkinaserne for trombocytafledte vækstfaktorer (PDGF), PDGFR, og hæmmer PDGF-medierede cellulære signaler.
English: The primary efficacy variable was the rate of haematological response, reported as either complete haematological response, no evidence of leukaemia, or return to chronic phase CML using the same criteria as for the study in accelerated phase.
Danish: Den primære effektvariable var graden af hæmatologisk hovedrespons, rapporteret enten som fuldstændigt hæmatologisk respons, intet tegn på leukæmi, eller remission til CML i kronisk fase, med anvendelse af samme kriterier som i undersøgelsen med patienter i accelereret fase.
English: If you forget to take Imatinib Teva - If you forget a dose, take it as soon as you remember.
Danish: - Hvis du glemmer at tage en dosis, så tag den, så snart du kommer i tanker om det.
English: How long to take Imatinib Teva Keep taking Imatinib Teva every day for as long as your doctor tells you.
Danish: Bliv ved med at tage Imatinib Teva hver dag, så længe som lægen har foreskrevet det.
English: 20x1 hard capsules 60 hard capsules 60x1 hard capsules 120 hard capsules 120x1 hard capsules 180x1 hard capsules
Danish: 20x1 hårde kapsler 60 hårde kapsler 60x1 hårde kapsler 120 hårde kapsler 120x1 hårde kapsler 180x1 hårde kapsler
English: If cytopenia is unrelated to leukaemia, reduce dose of imatinib to 260 mg/m2.
Danish: Hvis cytopeni ikke er leukæmirelateret, reducér Imatinib Teva-dosis til 260 mg/m2.
English: Ara-C 1,000 mg/m2/12 h i.v.
Danish: Ara-C 1.000 mg/m2/12 timer i.v.
English: Study ADE04 Prephase
Danish: Studie ADE04
English: Imatinib Teva may cause your body to retain water (severe fluid retention).
Danish: Imatinib Teva kan forårsage, at din krop begynder at ophobe væske (svær væskeretention).
English: The most commonly reported (≥ 10%) drug-related adverse reactions in both settings were mild nausea, vomiting, diarrhoea, abdominal pain, fatigue, myalgia, muscle cramps and rash.
Danish: De mest almindelige rapporterede (≥10%) lægemiddelrelaterede bivirkninger var i begge patientgrupper: let kvalme, opkastning, diarré, abdominalsmerter, træthed, myalgi og muskelkramper samt udslæt.
English: One phase II, open label, multicentre clinical trial (study B2225) was conducted including 12 patients with DFSP treated with imatinib 800 mg daily.
Danish: Der er udført et åbent multicenter fase II-klinisk forsøg (studie B2225) med inklusion af 12 patienter med DFSP, som blev behandlet med Imatinib Teva 800 mg daglig.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/12/808/001-020
Danish: EU/1/12/808/00120
English: BM = bone marrow, PB = peripheral blood 2 Cytogenetic response criteria:
Danish: BM = Knoglemarv, PB = Perifert blod
English: Iron oxide black (E172) Propylene glycol
Danish: Jernoxid sort (E172) Propylenglykol
English: SPECIAL STORAGE CONDITIONS Store below 30°C
Danish: Må ikke opbevares ved temperaturer over 30°C.
English: 6-MP (75 mg/m2/day, PO): days 8-28
Danish: 6-MP (75 mg/m2/dag, p.o.): dag 8-28
English: If cytopenia is unrelated to leukaemia, reduce dose of imatinib to 400 mg.
Danish: Hvis cytopeni ikke er leukæmirelateret, reducér Imatinib Teva-dosis til 400 mg.
English: 30 film-coated tablets 30x1 film-coated tablets 90 film-coated tablets 90x1 film-coated tablets
Danish: 30 filmovertrukne tabletter 30x1 filmovertrukne tabletter 90 filmovertrukne tabletter 90x1 filmovertrukne tabletter
English: (3 h), days 1-4; Mitoxantrone 10 mg/m2 i.v.
Danish: (3 timer), dag 1-4; mitoxantron 10 mg/m2 i.v.
English: Except in newly diagnosed chronic phase CML, there are no controlled trials demonstrating a clinical benefit, such as improvement in disease-related symptoms or increased survival.
Danish: Der er ingen kontrollerede undersøgelser, undtagen hos nyligt diagnosticerede kronisk fase CML-patienter,der har vist klinisk bedring såsom forbedring af sygdomsrelaterede symptomer eller øget overlevelse.
English: Paediatric chronic phase CML (at dose 340 mg/m2)
Danish: Børn med CML i kronisk fase (ved en dosis på 340 mg/m2)
English: Imatinib was teratogenic in rats when administered during organogenesis at doses ≥ 100 mg/kg, approximately equal to the maximum clinical dose of 800 mg/day, based on body surface area.
Danish: Imatinib var teratogent hos rotter ved administration under organgenese ved doser ≥100 mg/kg, ca.
English: The capsules are approximately 23 mm long and 9 mm wide.
Danish: Kapslerne er ca. 23 mm lange og 9 mm brede.
English: The capsules are approximately 19 mm long and 7 mm wide.
Danish: Kapslerne er ca. 19 mm lange og 7 mm brede.
English: Seven years after the last patient had been recruited, the median duration of first-line treatment was 82 and 8 months in the imatinib and IFN arms, respectively.
Danish: Medianvarigheden af førstevalgsbehandling var henholdsvis 82 og 8 måneder i imatinib- og INFarmene syv år efter, at den sidste patient var rekrutteret.
English: Partial
Danish: Delvist
English: 9/l and/or platelets < 10 x 109/l
Danish: 9/l og/eller trombocytter < 10 x 109/l
English: - The other ingredients are calcium hydrogen phosphate, crospovidone and magnesium stearate.
Danish: - Øvrige indholdsstoffer: calciumhydrogenphosphat, Crospovidon og magnesiumstearat.
English: For adult patients with relapsed or refractory Ph+ALL imatinib monotherapy at 600 mg/day is safe, effective and can be given until disease progression occurs.
Danish: Imatinib Teva monoterapi med 600 mg/dag er sikker og effektiv hos voksne patienter med recidiverende eller refraktiv Ph+ALL, og kan gives indtil der sker sygdomsprogression.
English: The compound selectively inhibits proliferation and induces apoptosis in Bcr-Abl positive cell lines as well as fresh leukaemic cells from Philadelphia chromosome positive CML and ALL patients.
Danish: Stoffet hæmmer selektivt proliferationen og inducerer apoptosis i Bcr-Abl-positive cellelinier såvel som i friske leukæmiceller fra Philadelphia-kromosompositiv (Ph+) CML og hos patienter med akut lymfoblastisk leukæmi (ALL).
English: The dose of 340 mg/m2 daily is recommended for children with Ph+ ALL (not to exceed the total dose of 600 mg).
Danish: Den anbefalede daglige dosis er 340 mg/m2 til børn med Ph+ALL (den totale dosis må dog ikke overstige 600 mg).
English: The tablets are approximately 20 mm long and 10 mm wide.
Danish: Tabletterne er ca. 20 mm lange og 10 mm brede.
English: Imatinib administration to patients without the genetic translocation generally results in no improvement.
Danish: Der ses generelt ingen bedring ved indgift af Imatinib Teva til patienter uden genetisk translokation.
English: • Adult and paediatric patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) integrated with chemotherapy.
Danish: • Voksne patienter og pædiatriske patienter med nydiagnosticeret Philadelphiakromosom positiv akut lymfoblastær leukæmi (Ph+ ALL) integreret med kemoterapi.
English: In GIST the study drug was discontinued for drug-related adverse reactions in 4% of patients.
Danish: Hos 4% af GIST-patienterne blev undersøgelsesmedicinen seponeret på grund af lægemiddelrelaterede bivirkninger.
English: 20x1 film-coated tablets 60 film-coated tablets 60x1 film-coated tablets 120 film-coated tablets 120x1 film-coated tablets 180x1 film-coated tablets
Danish: 20x1 filmovertrukne tabletter 60 filmovertrukne tabletter 60x1 filmovertrukne tabletter 120 filmovertrukne tabletter 120x1 filmovertrukne tabletter 180x1 filmovertrukne tabletter
English: Posology for MDS/MPD The recommended dose of Imatinib Teva is 400 mg/day for adult patients with MDS/MPD.
Danish: Dosering ved MDS/MPD Den anbefalede dosis af Imatinib Teva er 400 mg/dag til voksne patienter med MDS/MPD.
English: Very common (may affect more than 1 in 10 people) or common (may affect up to 1 in 10 people):
Danish: Meget almindelige (kan forekomme hos flere end 1 ud af 10 mennesker ) eller almindelige (kan forekomme hos op til 1 ud af 10 mennesker):
English: If cytopenia persists for 4 weeks and is still unrelated to leukaemia, stop imatinib until ANC ≥ 1 x 109/l and platelets ≥ 20 x 109/l, then resume treatment at 300 mg.
Danish: Hvis cytopeni vedvarer i 4 uger og stadig ikke er leukæmirelateret, seponér Imatinib Teva-behandling indtil ANC ≥ 1,0 x 109/l og trombocytter ≥ 20 x 109/l og genoptag herefter behandlingen med 300 mg.
English: Special precautions for disposal
Danish: EVENTUELLE SÆRLIGE FORHOLDSREGLER VED BORTSKAFFELSE AF IKKE
English: Uncommon (may affect up to 1 in 100 people) or rare (may affect up to 1 in 1,000 people):
Danish: Ikke almindelige (kan forekomme hos op til 1 ud af 100 mennesker) til sjældne (kan forekomme hos op til 1 ud af 1.000 mennesker):
English: (1 h) days 4-5; Ara-C 2x 2 g/m2 i.v.
Danish: (1 time) dag 4-5; Ara-C 2x 2 g/m2 i.v.
English: What you need to know before you take Imatinib Teva
Danish: Det skal du vide, før du begynder at tage Imatinib Teva
English: If cytopenia persists for 4 weeks and is still unrelated to leukaemia, stop Imatinib until ANC ≥ 1 x 109/l and platelets ≥ 20 x 109/l, then resume treatment at 200 mg/m2.
Danish: Hvis cytopeni vedvarer i 4 uger og stadig ikke er leukæmirelateret, seponér Imatinib Teva-behandlingen indtil ANC ≥ 1,0 x 109l og trombocytter ≥ 20 x 109l og genoptag behandling med 200 mg/m2.
English: The recommended dose of Imatinib Teva is 600 mg/day for adult patients with Ph+ ALL.
Danish: Den anbefalede dosis af Imatinib Teva er 600 mg/dag til voksne patienter med Ph+ ALL.
English: One open label, multicentre, phase II clinical trial (study B2225) was conducted testing imatinib in diverse populations of patients suffering from life-threatening diseases associated with Abl, Kit or PDGFR protein tyrosine kinases.
Danish: Der er udført et åbent multicenter, klinisk fase II-studie (studie B2225) med henblik på vurdering af Imatinib Teva i en blandet patientpopulation med livstruende sygdomme forbundet med Abl, Kit eller PDGFR protein-tyrosinkinaser.
English: Clinical cases of hypothyroidism have been reported in thyroidectomy patients undergoing levothyroxine replacement during treatment with imatinib (see section 4.5).
Danish: Kliniske tilfælde af hypotyroidisme er rapporteret hos patienter, der har fået foretaget tyroidektomi, og som er i levothyroxin-erstatningsterapi samtidig med imatinib -behandling (se pkt.
English: The printing ink is composed of shellac, iron oxide black (E172) and propylene glycol.
Danish: Prægeblækket består af shellac sort jernoxid (E 172) og propylenglycol.
English: For doses of 400 mg and above (see dose recommendation below) a 400 mg film-coated tablet is available.
Danish: Til doser på 400 mg og derover (se anbefalede doser nedenfor) er en 400 mg filmovertrukken tablet tilgængelig.
English: In study I2301, a total of 93 paediatric, adolescent and young adult patients (from 1 to 22 years old) with Ph+ ALL were enrolled in an open-label, multicentre, sequential cohort, non-randomized phase III trial, and were treated with imatinib (340 mg/m2/day) in combination with intensive chemotherapy after induction therapy.
Danish: I studie I2301 blev der inkluderet i alt 93 børn, unge og yngre voksne (fra 1 til 22 år) med Ph+ALL i et åbent, multicenter, ikke-radomiseret fase III sekventielt kohorte-forsøg.
English: • Feeling sick (nausea) with diarrhoea and vomiting, abdominal pain or fever (signs of bowel problems).
Danish: • Have kvalme med diarré og opkastning, mavesmerter eller feber (tegn på tarmproblemer).
English: Major cytogenetic response2
Danish: 2 Cytogenetiske responskriterier:
English: For doses other than 400 mg and 800 mg (see dose recommendation below) a 100 mg hard capsule is available.
Danish: Til andre doser end 400 mg og 800 mg (se anbefalede doser nedenfor) er en 100 mg hård kapsel tilgængelig.
English: 600 mg to be taken as 1 tablet of 400 mg plus 2 tablets of 100 mg or as 1 ½ tablets of 400 mg once a day.
Danish: 600 mg som skal tages som én tablet af 400 mg plus 2 tabletter af 100 mg eller som halvanden 400 mg tablet én gang daglig.
English: Active substances that may increase imatinib plasma concentrations Substances that inhibit the cytochrome P450 isoenzyme CYP3A4 activity (e.g. protease inhibitors such as indinavir, lopinavir/ritonavir, ritonavir, saquinavir, telaprevir, nelfinavir, boceprevir; azole antifungals including ketoconazole, itraconazole, posaconazole, voriconazole; certain macrolides such as erythromycin, clarithromycin and telithromycin) could decrease metabolism and increase imatinib concentrations.
Danish: Aktive stoffer der kan øge plasmakoncentrationen af imatinib Stoffer der hæmmer cytochrom P450 isoenzym CYP3A4-aktivitet (f.eks. proteasehæmmere som f.eks. indinavir, lopinavir/ritonavir, ritonavir, saquinavir, teleprevir, nelfinavir, boceprevir; azolantimykotika inklusiv ketoconazol, itraconazol, posaconazol, voriconazol; bestemte makrolider som f.eks. erythromycin, clarithromycin og telithromycin) kan nedsætte metabolismen og øge koncentrationen af imatinib.
English: CHR: Study 0110 [WBC < 10 x 109/l, platelets < 450 x 109/l, myelocyte+metamyelocyte < 5% in blood, no blasts and promyelocytes in blood, basophils < 20%, no extramedullary involvement] and in studies 0102 and 0109 [ANC ≥ 1.5 x 109/l, platelets ≥ 100 x 109/l, no blood blasts, BM blasts < 5% and no extramedullary disease] NEL Same criteria as for CHR but ANC ≥ 1 x 109/l and platelets ≥ 20 x 109/l (0102 and 0109 only) RTC < 15% blasts BM and PB, < 30% blasts+promyelocytes in BM and PB, < 20% basophils in PB, no extramedullary disease other than spleen and liver (only for 0102 and 0109).
Danish: CHR: Undersøgelse 0110 [leukocytter <10 x 109/l, trombocytter <450 x 109/l, myelocyt+metamyelocyt <5% i blodet, ingen blaster eller promyelocytter i blodet, basophiler <20%, ingen ekstramedullær involvering] og i undersøgelse 0102 og 0109 [ANC ≥1,5 x 109/l, trombocytter ≥100 x 109/l, ingen blaster i blodet, BM-blaster <5% og ingen ekstramedullær sygdom]
English: (1 h), days 1-3; Vincristine 1.3 mg/m2 i.v., days 1, 8, 15, 21;
Danish: (1 time), dag 1-3; vinkistin 1,3 mg/m2 i.v., dag 1, 8, 15, 21; prednisolon 60
English: Crospovidone Magnesium stearate Silica colloidal, anhydrous
Danish: Crospovidon Magnesiumstearat Kolloid vandfri silica
English: Posology for HES/CEL The recommended dose of Imatinib Teva is 100 mg/day for adult patients with HES/CEL.
Danish: Dosering ved HES/CEL Den anbefalede dosis af Imatinib Teva er 100 mg/dag til voksne patienter med HES/CEL.
English: The doctor will tell you how many capsules of Imatinib Teva to give to your child.
Danish: Lægen vil fortælle dig, hvor mange Imatinib Teva-kapsler, du skal give dit barn.
English: Remission induction
Danish: Remissionsinduktion
English: DEX 40 mg/day on days 1-4 and 11-14, alternated with MTX 1 g/m2 i.v.
Danish: (24 timer), dag 4; DEX 40 mg/dag på dag 1-4 og 11-14, supplerende med MTX 1 g/m2 i.v.
English: - Patients who are concerned about their fertility while taking Imatinib Teva are advised to consult with their doctor.
Danish: - Hvis du er bekymret for din frugtbarhed, mens du tager Imatinib Teva, skal du kontakte din læge.
English: doses)iii: days 2, 3, 16, and 17
Danish: eller p.o. q6h x 6 doser)iii: dag 2, 3, 16, og 17
English: The doctor will tell you how many tablets of Imatinib Teva to give to your child.
Danish: Lægen vil fortælle dig, hvor mange Imatinib Teva-tabletter, du skal give dit barn.
English: For doses other than 400 mg and 800 mg (see dose recommendation below) a 100 mg film-coated tablet is available.
Danish: Ved andre doser end 400 mg og 800 mg (se anbefalede doser nedenfor) er en 100 mg filmovertrukken tablet tilgængelig.
English: The recommended dosage of Imatinib Teva is 400 mg/day for adult patients in chronic phase CML.
Danish: Den anbefalede dosis af Imatinib Teva er 400 mg/dag til voksne patienter med CML i kronisk fase.
English: If you take more Imatinib Teva than you should If you have accidentally taken too many capsules, talk to your doctor straight away.
Danish: Hvis du ved et uheld har indtaget for mange kapsler, skal du kontakte din læge med det samme.
English: The dose is 800 mg per day (2 tablets), to be taken as 1 tablet in the morning and a second tablet in the evening.
Danish: Dosis er 800 mg pr. dag (2 tabletter), som skal tages som 1 tablet om morgenen og 1 tablet om aftenen.
English: Dark yellow to brownish orange round film-coated tablets with a score line on one side.
Danish: Mørk gul til brunlig-orange rund filmovertrukken tablet med delekærv på den ene side.
English: The tablet is debossed with “IT” and “1” at each side of the score line.
Danish: Tabletten er indgraveret med ”IT” på den ene side af delekærven og ”1” på den anden side af delekærven.