FrancophonIA/ELRC3.0 huggingface dataset:
English: Over the 12-week period, 24% (151 out of 640) of patients who received Resolor 2 mg completely emptied their bowels at least three times a week, compared with 11% (73 out of 645) of patients who received placebo.
Danish: I løbet af perioden på 12 uger fik 24 % (151 ud af 640) af de patienter, der fik Resolor i doser på 2 mg, fuldstændigt udtømt deres tarme mindst tre gange om ugen sammenlignet med 11 % (73 ud af 645) af de patienter, der fik placebo.
English: Resolor (2 or 4 mg once a day) was compared with placebo (a dummy treatment) in three main studies involving 1,999 patients with chronic constipation, 88% of whom were women.
Danish: Resolor (2 eller 4 mg én gang dagligt) blev sammenlignet med placebo (en uvirksom behandling) i tre hovedundersøgelser med 1 999 patienter med kronisk forstoppelse, hvoraf 88 % var kvinder.
English: What is Resolor?
Danish: Hvad er Resolor?
English: In the study of men with chronic constipation, 38% of patients treated with Resolor 2 mg (67 out of 177) completely emptied their bowels at least three times a week, compared with 18% of those given placebo (32 out of 181).
Danish: I undersøgelsen af mænd med kronisk forstoppelse udtømte 38 % af de patienter, der modtog Resolor i doser på 2 mg (67 ud af 177), deres tarme fuldstændigt mindst tre gange om ugen sammenlignet med 18 % af de patienter, der fik placebo (32 ud af 181).
English: For the full list of all side effects reported with Resolor, see the package leaflet.
Danish: Den fuldstændige liste over indberettede bivirkninger ved Resolor fremgår af indlægssedlen.
English: What benefit has Resolor shown during the studies?
Danish: Hvilken fordel viser undersøgelserne, at der er ved Resolor?
English: How has Resolor been studied?
Danish: Hvordan blev Resolor undersøgt?
English: What is Resolor used for?
Danish: Hvad anvendes Resolor til?
English: How is Resolor used?
Danish: Hvordan anvendes Resolor?
English: EU Number
Danish: ANVENDELSE EU nummer Navn
English: Name
Danish: Styrke
English: Treatment should be symptomatic.
Danish: Behandlingen skal være symptomatisk.
English: The plasma protein binding was > 98%.
Danish: Plasmaproteinbindingen var > 98 %.
English: ATCvet code: QC03CA04.
Danish: ATCvet-kode: QC03CA04.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 31/07/2015
Danish: DATO FOR FØRSTE TILLADELSE/FORNYELSE AF TILLADELSEN Dato for første markedsføringstilladelse: 31/07/2015
English: Any remaining tablet part should be discarded after 7 days.
Danish: Alle resterende tabletdele skal bortskaffes efter 7 dage.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains:
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hver tablet indeholder:
English: MARKETING AUTHORISATION NUMBER(S) EU/2/15/184/001-008
Danish: MARKEDSFØRINGSTILLADELSENS NUMMER (NUMRE) EU/2/15/184/001-008
English: Do not use this veterinary medicinal product after the expiry date which is stated on the carton.
Danish: Brug ikke dette veterinærlægemiddel efter den udløbsdato, der står på kartonen.
English: Tablets.
Danish: Tabletter.
English: A large proportion of the dose (between 61% and 70%) is excreted in the urine as unchanged parent drug.
Danish: En stor del af lægemidlet (fra 61 % til 70 %) udskilles i urinen som uændret udgangsstof.
English: Two metabolites (a dealkylated and a hydroxylated metabolite) were also identified in urine.
Danish: To metabolitter (en dealkyleret og en hydroxyleret metabolit) blev også identificeret i urinen.
English: 10 DATE OF REVISION OF THE TEXT {DD/MM/YYYY}
Danish: DATO FOR ÆNDRING AF TEKSTEN {DD/MM/ÅÅÅÅ}
English: The daily schedule of administration can be timed to control the period of micturition according to need.
Danish: Det daglige administrationsskema kan times for at kontrollere miktionsperioden i henhold til behovet.
English: While the animal is on treatment, these parameters should be monitored at very regular intervals according to the benefit-risk assessment performed by the responsible veterinarian.
Danish: Mens dyret er i behandling, skal disse parametre overvåges med meget regelmæssige intervaller i henhold til en vurdering af risk/benefit-forholdet, som udføres af den ansvarlige dyrlæge.
English: BATCH NUMBER Lot{number}
Danish: BATCHNUMMER Lot {nummer}
English: This in turn decreases free water reabsorption resulting in increased water excretion/urine production.
Danish: Dette nedsætter reabsorptionen af frit vand, hvilket fører til en øget vandudskillelse/urinproduktion.
English: Any part tablet should be stored in the blister pack or in a closed container for a maximum of 7 days.
Danish: Alle tabletdele skal opbevares i blisterpakningen eller i en lukket beholder i maksimalt 7 dage.
English: Feeding significantly increased torasemide AUClast by 36% on average and slightly delayed Tmax but no significant impact on Cmax was detected.
Danish: Fodring øgede AUClast for torasemid signifikant med i gennemsnit 36 % og en let forsinket Tmax, men der blev ikke detekteret nogen signifikant påvirkning af Cmax.
English: As a result of the diuretic action of torasemide, haemoconcentration and, very commonly, polyuria and/or polydipsia are observed.
Danish: Som et resultat af torasemids diuretiske virkning observeres der hæmokoncentration og, meget almindeligt, polyuri og/eller polydipsi.
English: Doses greater than 0.8 mg/kg/day have not been evaluated in the target animal safety or controlled clinical studies.
Danish: Doseringer over 0,8 mg/kg/dag er ikke blevet evalueret i sikkerhedsstudier eller kontrollerede kliniske studier med måldyret.
English: Vétoquinol SA Magny-Vernois 70200 Lure FRANCE
Danish: Vétoquinol SA Magny-Vernois 70200 Lure Frankrig
English: STATEMENT OF THE ACTIVE SUBSTANCE(S) AND OTHER INGREDIENT(S) Each tablet contains:
Danish: ANGIVELSE AF DE(T) AKTIVE STOF(FER) OG ANDRE INDHOLDSSTOFFER Hver tablet indeholder:
English: Loop diuretics mainly inhibit the Na+/2Cl-/K+ carrier from the luminal side of the cell.
Danish: Slyngediuretika hæmmer primært Na+/2Cl-/K+-transporteren fra cellens luminale side.
English: EU/2/15/184/001 30 tablets of 0.75 mg EU/2/15/184/002 100 tablets of 0.75 mg EU/2/15/184/003 30 tablets of 3 mg EU/2/15/184/004 100 tablets of 3 mg EU/2/15/184/005 30 tablets of 7.5 mg EU/2/15/184/006 100 tablets of 7.5 mg EU/2/15/184/007 30 tablets of 18 mg EU/2/15/184/008 100 tablets of 18 mg
Danish: EU/2/15/184/001 30 tabletter med 0,75 mg EU/2/15/184/002 100 tabletter med 0,75 mg EU/2/15/184/003 30 tabletter med 3 mg EU/2/15/184/004 100 tabletter med 3 mg EU/2/15/184/005 30 tabletter med 7,5 mg EU/2/15/184/006 100 tabletter med 7,5 mg EU/2/15/184/007 30 tabletter med 18 mg EU/2/15/184/008 100 tabletter med 18 mg
English: UpCard tablets can be administered with or without food.
Danish: UpCard tabletter kan administreres sammen med eller uden mad.
English: Increase in renal blood parameters and renal insufficiency are very commonly observed during treatment.
Danish: Forhøjede nyreparametre i blodet og nyreinsufficiens observeres meget almindeligt i løbet af behandlingen.
English: Do not use concomitantly with other loop diuretics.
Danish: Bør ikke anvendes samtidigt med andre slyngediuretika.
English: WITHDRAWAL PERIOD Not applicable.
Danish: TILBAGEHOLDELSESTID Ikke relevant.
English: Polychlorotrifluoroethylene-PVC/aluminium blister pack (each blister pack contains 10 tablets) and is packaged in an outer cardboard box.
Danish: Polychlortrifluorethylen-PVC/aluminium blisterpakning (hver blisterpakning indeholder 10 tabletter) og den er pakket i en ydre kartonæske.
English: Torasemide is secreted into the tubule lumen via the probenecid-sensitive organic acid transport system.
Danish: Torasemid secerneres i tubuluslumen via det probenecid-følsomme organiske syretransportsystem.
English: Frequent re-examinations of the dog will enhance the establishment of an appropriate diuretic dose.
Danish: Hyppige gentagne undersøgelser af hunden vil gøre det nemmere at etablere en passende diuretisk dosis.
English: All strengths are available in the following pack sizes: Pack sizes of 30 or 100 tablets.
Danish: Alle styrker fås i de følgende pakningsstørrelser: Pakningsstørrelser på 30 eller 100 tabletter.
English: Occurrence of soft faeces is transient, mild, and does not necessitate the withdrawal of the treatment.
Danish: Forekomsten af blød afføring er forbigående, let og det er ikke nødvendigt at afbryde behandlingen.
English: DATE ON WHICH THE PACKAGE LEAFLET WAS LAST APPROVED Detailed information on this product is available on the website of the European Medicines Agency (http://www.ema.europa.eu/).
Danish: DATO FOR SENESTE GODKENDELSE AF INDLÆGSSEDLEN Yderligere information om dette lægemiddel er tilgængelig på Det Europæiske Lægemiddelagenturs hjemmeside (http://www.ema.europa.eu).
English: Since protein binding facilitates the renal secretion of torasemide, a decrease in binding due to displacement by another drug may be a cause of diuretic resistance.
Danish: Da proteinbinding faciliterer nyreudskillelsen af torasemid, kan en reduceret binding som følge af, at lægemidlet blev fordrevet fra bindingsstedet af et andet lægemiddel, være en årsag til diuretisk resistens.
English: After repeated administration to dogs at 0.2 mg/kg daily for 14 days, no plasma accumulation of torasemide was detected.
Danish: Efter en gentagen administration til hunde med 0,2 mg/kg dagligt i 14 dage, blev der ikke detekteret nogen plasmaakkumulation af torasemid.
English: Renal function, hydration status and serum electrolytes status should be monitored: - At treatment initiation - from 24 hours to 48 hours after treatment initiation - from 24 hours to 48 hours after dose change - In case of adverse events.
Danish: Nyrefunktion, status af hydrering og serum-elektrolytter bør overvåges: - Når behandlingen påbegyndes - Fra 24 timer til 48 timer efter behandlingsstart - Fra 24 timer til 48 timer efter en dosisændring - I tilfælde af uønsket hændelser.
English: The main site of action is the medullary portion of the ascending limb of the loop of Henle.
Danish: Det primære virkningssted er den medullære del af det opadstigende ben i Henles slynge.
English: Keep tablets in the blister packs until required, and keep the blisters in the outer carton.
Danish: Opbevar tabletterne i blisterpakningen indtil der er brug for dem, og opbevar blisterkortene i den ydre karton.
English: Inhibition of sodium and chloride ion reabsorption not only results in saluresis but also a decrease in interstitial osmolarity within the renal medulla.
Danish: Når reabsorptionen af natrium- og chloridioner hæmmes fører det ikke kun til salurese, men også til en nedsat interstitiel osmolaritet i den renale medulla.
English: When used in combination with cardiac treatments (e.g. ACE-inhibitors, digoxin), the dose regimen may need to be modified depending upon the animal's response to therapy.
Danish: Når de anvendes i kombination med hjertebehandlinger (f.eks. ACE-hæmmere, digoxin), kan det være nødvendigt at ændre dosisprogrammet, afhængigt af dyrets respons på behandlingen.
English: The use of UpCard is not recommended during pregnancy, lactation and in breeding animals.
Danish: Anvendelse af UpCard frarådes bør ikke anvendes under drægtighed, laktation og til avlsdyr.
English: Concomitant use with veterinary medicinal products affecting electrolyte balance (corticosteroids, amphotericin B, cardiac glycosides, other diuretics) requires careful monitoring.
Danish: Anvendelse sammen med veterinærlægemidler, der påvirker elektrolytbalancen (kortikosteroider, amphotericin B, hjerteglykosider, andre diuretika) kræver nøje overvågning.
English: 4.4 Special warnings for each target species None.
Danish: 4.4 Særlige advarsler for hver enkelt dyreart, som lægemidlet er beregnet til Ingen.
English: Based on a pharmacodynamics modelling study conducted in healthy dogs at doses of 0.1 and 0.6 mg torasemide/kg, a single dose of torasemide had approximately 20 times the diuretic effect of a single dose of furosemide.
Danish: Baseret på et farmakodynamisk modelleringsstudie udført med raske hunde ved doser på 0,1 og 0,6 mg torasemid/kg havde en enkelt dosis torasemid ca. 20 gange den diuretiske virkning af en enkelt dosis furosemid.
English: Do not use in case of severe dehydration, hypovolaemia or hypotension.
Danish: Bør ikke anvendes i tilfælde af svær dehydrering, hypovolæmi eller hypotension.
English: In case of accidental ingestion, particularly in the case of children, seek medical advice immediately and show the package leaflet or the label to the physician.
Danish: I tilfælde af indgift ved hændeligt uheld, især for børn, skal der straks søges lægehjælp, og indlægssedlen eller etiketten bør vises til lægen.
English: Once signs of congestive heart failure have been controlled and the patient is stable, if long term diuretic therapy with this product is required it should be continued at the lowest effective dose.
Danish: Når tegnene på kongestivt hjertesvigt er blevet kontrolleret og patienten er stabil, bør der fortsættes med den laveste effektive dosis, hvis det er nødvendigt med langvarig diuretisk behandling med præparatet.
English: After a single oral dose of 0.1 mg/kg, the oral absolute bioavailability corresponded to about 90%.
Danish: Efter en enkelt oral dosis på 0,1 mg/kg svarede den orale absolutte biotilgængelighed til ca. 90 %.
English: Torasemide is a loop diuretic of the pyridyl sulfonylurea class.
Danish: Torasemid er en slyngediuretikum af pyridylsulfonylurinstof-klassen.
English: This product may cause increased urination and/or gastrointestinal disturbances if ingested.
Danish: Dette præparat kan forårsage øget vandladning og/eller mave-tarm-forstyrrelser, hvis det indtages.
English: The dosage should be titrated to maintain patient comfort with attention to renal function and electrolytes status.
Danish: Doseringen skal titreres for at opretholde patientkomfort under hensyntagen til nyrefunktionen og elektrolytstatus.
English: Torasemide treatment should not be initiated in dogs already clinically stable on an alternative diuretic for treatment of the signs of congestive heart failure, except where this has been justified taking into account the risk of de-stabilising the clinical condition and of adverse reactions as indicated in section
Danish: Behandling med torasemid bør ikke påbegyndes hos hunde, der allerede er klinisk stabile med et alternativt diuretikum til behandling af tegn på kongestivt hjertesvigt, undtagen hvor dette er blevet berettiget ved at tage risikoen for destabilisering af den kliniske tilstand og af bivirkningerne indikeret i pkt.
English: If the level of diuresis requires alteration, the dose may be increased or decreased within the recommended dose range by increments of 0.1 mg/kg bodyweight.
Danish: Hvis det er nødvendigt at ændre diureseniveauet kan dosis øges eller nedsættes inden for det anbefalede dosisinterval med trin på 0,1 mg/kg legemsvægt.
English: Pharmacotherapeutic group: Cardiovascular system, high-ceiling diuretics, plain sulfonamides.
Danish: Farmakoterapeutisk gruppe: Kardiovaskulært system, højlofts-diuretika, usammensatte sulfonamider.
English: Torasemide can reduce the renal excretion of salicylates, leading to an increased risk of toxicity.
Danish: Torasemid kan nedsætte nyreudskillelsen af salicylater, og føre til en øget risiko for toksicitet.
English: In healthy dogs and after once daily administration for 5 days, the mean percentage of increase in excreted urine over 24 hours ranged between 33% and 50% at 0.15 mg/kg, between 181% and 328% at 0.4 mg/kg and between 264% and 418% at 0.75 mg/kg.
Danish: Hos raske hunde og efter administration én gang dagligt i 5 dage var den gennemsnitlige procentvise stigning i udskilt urin i løbet af 24 timer i intervallet fra 33 % til 50 % ved 0,15 mg/kg, fra 181 % til 328 % ved 0,4 mg/kg og fra 264 % til 418 % ved 0,75 mg/kg.
English: Do not use in case of renal failure.
Danish: Bør ikke anvendes i tilfælde af nyresvigt.
English: Torasemide should be used with caution in cases of diabetes mellitus, and in dogs with previously prescribed high doses of an alternative loop diuretic.
Danish: Torasemid bør anvendes med forsigtighed i tilfælde af diabetes mellitus, samt hos hunde, der tidligere har fået ordineret høje doser af et alternativt slyngediuretikum.
English: The effect of antihypertensive drugs, especially angiotensin converting enzyme (ACE)-inhibitors, may be potentiated when co-administered with torasemide.
Danish: Virkningen af antihypertensive lægemidler, især angiotensinkonverterende enzym (ACE)-hæmmere, kan forstærkes ved administration sammen med torasemid.
English: However, it is anticipated that overdose increases the risk of dehydration, electrolyte imbalance, renal insufficiency, anorexia, weight loss and cardiovascular collapse.
Danish: Det forventes imidlertid, at en overdosering øger risikoen for dehydrering, elektrolytforstyrrelser, nyreinsufficiens, anoreksi, vægttab and kardiovaskulært kollaps.
English: ADVICE ON CORRECT ADMINISTRATION UpCard tablets can be administered with or without food.
Danish: OPLYSNINGER OM KORREKT ANVENDELSE UpCard tabletter kan administreres sammen med eller uden mad.
English: UpCard tablets are supplied in blister packs with 10 tablets per blister pack.
Danish: UpCard tabletter fås i blisterpakninger med 10 tabletter pr. blisterpakning.
English: The parent drug is metabolised by the hepatic cytochrome P450 families 3A4 and 2E1, and to a lesser extent by 2C9.
Danish: Udgangsstoffet metaboliseres af cytokrom P450-familierne 3A4 og 2E1 i leveren, og i mindre grad af 2C9.
English: Pack sizes are of 30 or 100 tablets.
Danish: Pakningsstørrelser er på 30 eller 100 tabletter.
English: The safety of the veterinary medicinal product has not been established during pregnancy or lactation.
Danish: Lægemidlets sikkerhed under drægtighed eller laktation er ikke fastlagt.
English: Concomitant use with aminoglycosides or cephalosporins may increase the risk of nephrotoxicity and ototoxicity.
Danish: Anvendelse sammen med aminoglykosider eller cefalosporiner kan øge risikoen for nefrotoksicitet og ototoksicitet.
English: NAME OF THE MARKETING AUTHORISATION HOLDER Vétoquinol SA
Danish: NAVN PÅ INDEHAVEREN AF MARKEDSFØRINGSTILLADELSEN Vétoquinol SA
English: Marketing authorisation holder and manufacturer responsible for batch release: Vétoquinol SA
Danish: Indehaver af markedsføringstilladelsen og fremstiller ansvarlig for batchfrigivelse: Vétoquinol SA
English: A. MANUFACTURER RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. STATEMENT OF THE MRLs
Danish: A. FREMSTILLER ANSVARLIG FOR BATCHFRIGIVELSE B. BETINGELSER ELLER BEGRÆNSNINGER VEDRØRENDE UDLEVERING OG
English: The oral absorption was fast with mean Tmax at 0.93 hours after administration of 0.1 mg/kg.
Danish: Den orale absorption var hurtig med en gennemsnitlig Tmax på 0,93 timer efter administration af 0,1 mg/kg.
English: Dose proportionality for Cmax and AUCinf was demonstrated between 0.2 and 1.6 mg/kg.
Danish: Der blev demonstreret dosisproportionalitet for Cmax og AUCinf fra 0,2 til 1,6 mg/kg.
English: Concurrent use of drugs that increase the risk of renal injury or renal insufficiency should be avoided.
Danish: Samtidig anvendelse af lægemidler, der øger risikoen for nyreskade eller nyresvigt, bør undgås.
English: Erythema of the inner pinnae may be observed.
Danish: Der kan observeres erytem i det indre øre.
English: In dogs, after a single intravenous dose at 0.1 mg/kg, the total body clearance was 0.017 L/h·kg, the volume of distribution was 0.14 L/kg and the terminal half-life was 7.0 hours.
Danish: Efter en enkelt intravenøs dosis på 0,1 mg/kg til hunde, var den totale legemsclearance 0,017 l/t·kg, fordelingsvoluminet var 0,14 l/kg og den terminale halveringstid var 7,0 timer.
English: The tablets can be divided into equal halves.
Danish: Tabletterne kan deles i to lige store dele.
English: The majority of dogs are stabilised at a dose of torasemide less than or equal to 0.3 mg per kg bodyweight, once daily.
Danish: De fleste hunde stabiliseres ved en dosis torasemid under eller lig med 0,3 mg pr. kg legemsvægt, én gang dagligt.
English: In dogs with pre-existing electrolyte and/or water imbalance, this should be corrected prior to treatment with torasemide.
Danish: Hvis hundene har eksisterende forstyrrelser af elektrolyt- og/eller væskebalancen, bør dette korrigeres før behandling med torasemid.
English: The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment) - common (more than 1 but less than 10 animals in 100 animals) - uncommon (more than 1 but less than 10 animals in 1,000 animals) - rare (more than 1 but less than 10 animals in 10,000 animals) - very rare (less than 1 animal in 10,000 animals, including isolated reports).
Danish: Hyppigheden af bivirkninger er defineret som: - Meget almindelig (mere end 1 ud af 10 dyr, der viser bivirkning(er) i løbet af en behandling) - Almindelige (mere end 1, men mindre end 10 dyr i 100 dyr) - Ualmindelige (mere end 1, men mindre end 10 dyr i 1.000 dyr) - Sjældne (mere end 1, men mindre end 10 dyr ud af 10.000 dyr) - Meget sjælden (mindre end 1 dyr ud af 10.000 dyr, herunder isolerede rapporter)
English: Concomitant administration of torasemide with other drugs metabolised by cytochrome P450 families 3A4 (e.g. enalapril, buprenorphine, doxycycline, cyclosporine) and 2E1 (isoflurane, sevoflurane, theophylline) may decrease their clearance from the systemic circulation.
Danish: Administration af torasemid sammen med andre lægemidler, der metaboliseres af cytokrom P450familierne 3A4 (f.eks. enalapril, buprenorphin, doxycyklin, ciclosporin) og 2E1 (isofluran, sevofluran, theophyllin) kan nedsætte deres clearance fra det systemiske kredsløb.
English: In cases of prolonged treatment, electrolyte deficiency (including hypokalaemia, hypochloraemia, hypomagnesaemia) and dehydration may occur.
Danish: Ved langvarig behandling kan der opstå elektrolytmangel (herunder hypokaliæmi, hypochloræmi, hypomagnesæmi) og dehydrering.
English: Gastrointestinal signs which include emesis, reduced or absent faeces and, in rare cases, soft faeces may be observed.
Danish: Der kan observeres mave-tarm-problemer, som omfatter emese, nedsat eller ingen afføring og i sjældne tilfælde blød afføring.
English: In dogs presenting in acute crisis with pulmonary oedema, pleural effusion and/or ascites requiring emergency treatment, the use of injectable drugs should be considered first before commencing oral diuretic therapy.
Danish: Til hunde i akut krise med lungeødem, pleuraeffusion og/eller ascites, hvor akut behandling er nødvendig, bør det overvejes først at anvende injicerbare lægemidler, før behandling med orale diuretika påbegyndes.
English: The tablets can be divided into equal quarters.
Danish: Tabletterne kan deles i fire lige store dele.
English: Care should be exercised when administering torasemide with other highly plasma protein bound drugs.
Danish: Der bør udvises forsigtighed, når torasemid administreres sammen med andre lægemidler, der i høj grad er bundet til plasmaproteiner.
English: The recommended dose of torasemide is 0.1 to 0.6 mg per kg bodyweight, once daily.
Danish: Den anbefalede dosis torasemid er 0,1 til 0,6 mg pr. kg legemsvægt én gang dagligt.
English: The AUCinf corresponded to 6.3 µg·h/mL after a single oral dose of 0.1mg/kg and to 153.6 µg·h/mL after a single oral dose of 1.6 mg/kg.
Danish: AUCinf svarede til 6,3 µg·t/ml efter en enkelt oral dosis på 0,1 mg/kg og til 153,6 µg·t/ml efter en enkelt oral dosis på 1,6 mg/kg.
English: 0.75 mg torasemide 3 mg torasemide 7.5 mg torasemide 18 mg torasemide
Danish: 0,75 mg torasemid 3 mg torasemid 7,5 mg torasemid 18 mg torasemid
English: The maximum plasma concentrations Cmax corresponded to 1.1 µg/mL after a single oral dose of 0.1 mg/kg and to 19 µg/mL after a single oral dose of 1.6 mg/kg.
Danish: De maksimale plasmakoncentrationer Cmax svarede til 1,1 µg/ml efter en enkelt oral dosis på 0,1 mg/kg og til 19 µg/ml efter en enkelt oral dosis på 1,6 mg/kg.