FrancophonIA/ELRC3.0 huggingface dataset:
English: Xagrid is a medicine which interferes with the development of platelets.
Danish: Xagrid er et lægemiddel, der griber ind i udviklingen af blodplader.
English: 9/l and ideally at levels between 150 x 10 9/l and 400 x 10 9/l.
Danish: 9/l og ideelt på et niveau mellem 150 x 10
English: If you forget to take Xagrid
Danish: Hvis De har glemt at tage Xagrid
English: • At the doses recommended for use in the treatment of essential thrombocythaemia, anagrelide may potentiate the effects of other medicinal products that inhibit or modify platelet function e.g. acetylsalicylic acid.
Danish: • Ved de doser, der anbefales til brug ved behandling af essentiel trombocytæmi, kan anagrelid forstærke virkningen af andre lægemidler, der hæmmer eller modificerertrombocytfunktionen, f.eks. acetylsalicylsyre.
English: Caution should be taken when using anagrelide in patients with known risk factors for prolongation of the QT interval, such as congenital long QT syndrome, a known history of acquired QTc prolongation, medicinal products that can prolong QTc interval and hypokalaemia.
Danish: Der skal udvises forsigtighed, når anagrelid bruges hos patienter med kendte risikofaktorer for forlængelse af QT-intervallet, såsom medfødt langt QT-syndrom, anamnese med erhvervet QTcforlængelse, lægemidler, der kan forlænge QTc-intervallet, samt hypokaliæmi.
English: • In vivo interaction studies in humans have demonstrated that digoxin and warfarin do not affect the pharmacokinetic properties of anagrelide.
Danish: • In vivo interaktions studier hos mennesker har påvist, at digoxin og warfarin ikke påvirker anagrelids farmakokinetiske egenskaber.
English: Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.
Danish: Fortæl altid lægen eller apotekspersonalet, hvis De tager anden medicin eller har gjort det for nylig.
English: Therefore it is recommended that patients with moderate or severe hepatic impairment are not treated with anagrelide.
Danish: Det anbefales derfor, at patienter med moderat eller svært nedsat leverfunktion ikke behandles med anagrelid.
English: In the later study 3660 patients who received anagrelide at a mean dose of approximately 2 mg/day were assessed for safety.
Danish: I den senere undersøgelse blev 3660 patienter, der modtog anagrelid i en gennemsnitlig dosis på ca. 2 mg/dag, vurderet for sikkerhed.
English: Pharmacokinetic data from exposed fasting children and adolescents (age range 7 - 16 years) with essential thrombocythaemia indicate that dose normalised exposure, Cmax and AUC, of anagrelide tended to be higher in children/adolescents compared with adults.
Danish: Farmakokinetiske data fra eksponerede fastende børn og unge (i alderen 7-16 år) med essentiel trombocytæmi viser, at dosis-normaliseret eksponering, Cmax og AUC for anagrelid har en tendens til at være højere hos børn/unge i sammenligning med voksne.
English: OUTER CARTON AND BOTTLE LABEL
Danish: YDRE EMBALLAGE OG FLASKENS ETIKET
English: Pharmacokinetic data from fasting elderly patients with ET (age range 65 - 75 years) compared to fasting adult patients (age range 22 - 50 years) indicate that the Cmax and AUC of anagrelide were 36% and 61% higher respectively in elderly patients, but that the Cmax and AUC of the active metabolite, 3-hydroxy anagrelide, were 42% and 37% lower respectively in the elderly patients.
Danish: Farmakokinetiske data fra fastende ældre patienter med ET (i alderen 65-75 år) sammenlignet med fastende voksne patienter (i alderen 22-50 år) viser, at Cmax og AUC for anagrelid var henholdsvis 36 % og 61 % højere hos ældre patienter, hvorimod Cmax og AUC for den aktive metabolit 3-hydroxyanagrelid var henholdsvis 42 % og 37 % lavere hos ældre patienter.
English: Hypersensitivity to anagrelide or to any of the excipients listed in section 6.1.
Danish: Overfølsomhed over for anagrelid eller over for et eller flere af hjælpestofferne anført i punkt 6.1.
English: Therapy requires close clinical supervision of the patient which will include a full blood count (haemoglobin and white blood cell and platelet counts), assessment of liver function (ALT and AST), renal function (serum creatinine and urea) and electrolytes (potassium, magnesium and calcium).
Danish: Behandling kræver nøje klinisk overvågning af patienten, hvilket vil omfatte komplet blodtælling (hæmoglobin og hvide blodceller og blodpladetal), vurdering af leverfunktion (ALT og AST), test af nyrefunktion (serum-kreatinin og urea) samt elektrolytter (kalium, magnesium og calcium).
English: A transient increase in mean QTc was observed for both doses during periods of increasing heart rate and the maximum change in mean QTcF (Fridericia correction) was +5.0 msec occurring at 2 hours for 0.5 mg and +10.0 msec occurring at 1 hour for 2.5 mg.
Danish: Der blev observeret en forbigående forøget gennemsnitlig QTc for begge doser i løbet af perioderne med øget hjerterytme, og den maksimale ændring i gennemsnitlig QTcF (Fridericia-korrektion) var +5,0 msek., der opstod efter 2 timer for 0,5 mg, +10,0 msek., der opstod efter 1 time for 2,5 mg.
English: Tell your doctor if you are breast-feeding or if you are planning to breast-feed your baby.
Danish: Fortæl Deres læge, om De ammer, eller om De planlægger at amme Deres barn.
English: Therefore Xagrid is not recommended during pregnancy.
Danish: Derfor bør Xagrid ikke anvendes under graviditet.
English: Headache Dizziness Depression Amnesia
Danish: Hovedpine Svimmelhed Depression Amnesi
English: Do not crush the capsules or dilute the contents in a liquid.
Danish: De må ikke knuse kapslerne eller fortynde indholdet med væske.
English: Repeated dose toxicity
Danish: Toksicitet ved gentagne doser:
English: • If you have any problems with your liver or kidneys.
Danish: • Hvis De har problemer med lever eller nyrer.
English: Xagrid 0.5 mg hard capsules.
Danish: Xagrid 0,5 mg hårde kapsler.
English: • If you have moderate or severe liver problems;
Danish: • Hvis De har moderate eller svære leverproblemer;
English: Xagrid is indicated for the reduction of elevated platelet counts in at risk essential thrombocythaemia (ET) patients who are intolerant to their current therapy or whose elevated platelet counts are not reduced to an acceptable level by their current therapy.
Danish: Xagrid er indiceret til reduktion af forhøjet blodpladetal hos risikopatienter med essentiel trombocytæmi (ET), der ikke tåler deres nuværende behandling, eller hvis forhøjede blodpladetal ikke reduceres til et acceptabelt niveau med den aktuelle behandling.
English: Following repeated oral administration of anagrelide in dogs, subendocardial haemorrhage and focal myocardial necrosis was observed at 1mg/kg/day or higher in males and females with males being more sensitive.
Danish: Efter gentagen oral indgivelse af anagrelid hos hunde blev der observeret subendokardial blødning og fokal myokardial nekrose ved 1 mg/kg/dag eller derover hos han- og hunhunde, hvor hanhundene var mest følsomme.
English: What you need to know before you take Xagrid Do not take Xagrid
Danish: Det skal De vide, før De begynder at tage Xagrid Tag ikke Xagrid
English: Contents of the pack and other information What Xagrid contains
Danish: Pakningsstørrelser og yderligere oplysninger Xagrid indeholder:
English: • Medicines that can alter your heart rhythm e.g. sotalol, amiodarone;
Danish: • Medicin, der kan ændre Deres hjerterytme, f.eks. sotalol, amiodaron;
English: Reproductive toxicology
Danish: Reproduktiv toksikologi:
English: • If you were born with or have family history of prolonged QT interval (seen on ECG, electrical recording of the heart), or you are taking other medicines that result in abnormal ECG changes or if you have low levels of electrolytes e.g. potassium, magnesium or calcium (see section “Other medicines and Xagrid”);
Danish: • Hvis De har medfødt forlænget QT-interval, eller De har det i familien (kan ses på EKG'et, en registrering af hjertets elektriske aktivitet), eller De tager andre lægemidler, der fører til unormale EKG-ændringer, eller De har lavt indhold af salte, f.eks. kalium, magnesium eller calcium (se punkt ”Brug af anden medicin sammen med Xagrid”);
English: This contains a drying agent to keep the capsules dry.
Danish: Glasset indeholder også en lille forseglet beholder, som indeholder et tørremiddel til at holde kapslerne tørre.
English: Serious cardiovascular adverse events including cases of torsade de pointes, ventricular tachycardia, cardiomyopathy, cardiomegaly and congestive heart failure have been reported (see section 4.8).
Danish: Der er indberettet alvorlige kardiovaskulære bivirkninger, herunder tilfælde af torsade de pointes, ventrikulær takykardi, kardiomyopati, kardiomegali og kongestiv hjertesvigt (se pkt.
English: • Oral contraceptives: If you experience bad diarrhoea whilst taking this medicine, it may reduce how well the oral contraceptive works and use of an extra method of contraception is recommended (e.g condom).
Danish: • Svangerskabsforebyggende tabletter: Hvis De oplever svær diare, mens De tager dette lægemiddel, kan det nedsætte virkningen af svangerskabsforebyggende tabletter, og det anbefales at benytte en ekstra præventionsmetode (f.eks. kondom).
English: Capsule shell: gelatin and titanium dioxide (E171).
Danish: Kapselskal: gelatine og titandioxid (E171).
English: If you get any side effects talk to your doctor or pharmacist.
Danish: Hvis De oplever bivirkninger, bør De tale med Deres læge eller apoteket.
English: Capsule contents: povidone (E1201); crospovidone; lactose, anhydrous; lactose monohydrate; cellulose, microcrystalline (E460) and magnesium stearate.
Danish: Kapselindhold: povidon (E1201), crospovidon; lactose, vandfri; lactosemonohydrat; cellulose, mikrokrystallinsk (E460) og magnesiumstearat.
English: Among them, the incidence of adrenal phaeochromocytomas was increased relative to control in males at all dose levels (≥ 3 mg/kg/day) and in females receiving 10 mg/kg/day and above.
Danish: Blandt disse var en forøget forekomst af fæokromocytomer i binyrerne hos hanrotter sammenlignet med kontrollen på alle dosisniveauer (≥ 3 mg/kg/dag) og hos hunrotter, som modtog 10 mg/kg/dag og derover.
English: In a pre- and post-natal development study in female rats, anagrelide at oral doses of ≥10 mg/kg produced a non-adverse increase in gestational duration.
Danish: I et præ- og postnatalt udviklingsstudie med hunrotter førte anagrelid ved orale doser på ≥ 10 mg/kg til en ikke negativ forlængelse af gestationsvarigheden.
English: Angina pectoris Postural hypotension Vasodilatation
Danish: Kardiomyopati Kardiomegali Perikardieeffusion Angina pectoris Postural hypotension Vasodilatation
English: The usual starting dose of Xagrid is 1 mg. You take this dose as one capsule of 0.5 mg twice a day, for at least a week.
Danish: De tager denne dosis som en kapsel med 0,5 mg to gange dagligt i mindst én uge.
English: • Medicines used to treat heart disorders, for example, milrinone, enoximone, amrinone, olprinone and cilostazol;
Danish: • Medicin til behandling af hjertesygdomme, f.eks. milrinon, enoximon, amrinon, olprinon og cilostazol;
English: Xagrid should not be taken while breast-feeding.
Danish: Xagrid må ikke tages, medens man ammer.
English: • Inflammation of the liver, symptoms include nausea, vomiting, itching, yellowing of the skin and eyes, discoloration of stool and urine (hepatitis);
Danish: • Leverbetændelse, symptomer omfatter kvalme, opkastning, kløe, gulfarvning af hud og øjne, misfarvning af afføring eller urin (hepatitis);
English: Xagrid should not be taken by pregnant women.
Danish: Xagrid må ikke tages af gravide.
English: Strong ammonium solution Potassium hydroxide (E525) Black iron oxide (E172)
Danish: Stærk ammoniakopløsning Kaliumhydroxid (E525) Sort jernoxid (E172)
English: Package leaflet: Information for the patient Xagrid 0.5 mg hard capsules anagrelide
Danish: Indlægsseddel: Information til patienten Xagrid 0,5 mg hårde kapsler anagrelid
English: • Lung inflammation (signs include fever, coughing, difficulty breathing, wheezing; which causes scaring of the lungs) (allergic alveolitis, including interstitial lung disease, pneumonitis);
Danish: • Betændelseslignende reaktion (inflammation) i lungerne (tegn omfatter feber, hoste, vejrtrækningsbesvær, hvæsen; som forårsager dannelse af arvæv i lungerne) (allergisk alveolitis, herunder interstitiel lungesygdom, pneumonitis);
English: Other medicines and Xagrid
Danish: Brug af anden medicin sammen med Xagrid
English: Do not crush or dilute the contents in a liquid.
Danish: Indholdet må ikke knuses eller fortyndes i en væske.
English: Patients with moderate or severe hepatic impairment.
Danish: Patienter med moderat eller svær leverinsufficiens.
English: • If you have moderate or severe kidney problems.
Danish: • Hvis De har moderate eller svære nyreproblemer.
English: Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Danish: Bør ikke anvendes til patienter med arvelig galactoseintolerans, en særlig form af hereditær lactasemangel (Lapp lactase deficiency) eller glucose/galactosemalabsorption.
English: Printing ink: shellac; strong ammonium solution; potassium hydroxide (E525); black iron oxide (E172).
Danish: Trykkeblæk: shellac; stærk ammoniakopløsning; kaliumhydroxid (E525); sort jernoxid (E172).
English: • If you are allergic to anagrelide or any of the other ingredients of this medicine (listed in section
Danish: • Hvis De er allergisk over for anagrelid eller et af de øvrige indholdsstoffer i Xagrid (angivet i punkt 6).
English: Available data in animals have shown excretion of anagrelide/metabolites in milk.
Danish: De tilgængelige data fra dyre studier viser, at anagrelid/metabolitter udskilles i mælk.
English: Xagrid 0.5 mg hard capsules anagrelide
Danish: Xagrid 0,5 mg hårde kapsler anagrelid
English: Anagrelide at ≥60 mg/kg increased parturition time and mortality in the dam and foetus respectively.
Danish: Anagrelid ved ≥ 60 mg/kg forlængede fødselsperioden og forhøjede mortaliteten hos hhv. hunner og fostre.
English: Gastrointestinal haemorrhage Pancreatitis Anorexia Dyspepsia Constipation
Danish: Gastrointestinal blødning Pankreatitis Anoreksi Dyspepsi
English: Each hard capsule contains lactose monohydrate (53.7 mg) and anhydrous lactose (65.8 mg).
Danish: Hjælpestof(fer), som behandleren skal være opmærksom på Hver hård kapsel indeholder lactosemonohydrat (53,7 mg) og vandfri lactose (65,8 mg).
English: Women of child-bearing potential should use adequate birth-control measures during treatment with anagrelide.
Danish: Kvinder i den fertile alder Kvinder i den fertile alder bør anvende passende prævention under behandling med anagrelid.
English: How to take Xagrid
Danish: Sådan skal De tage Xagrid
English: Capsule shell Gelatin
Danish: Indkapsling Gelatine
English: A feeling of weakness or feeling unwell, high blood pressure, irregular heart beat, fainting, chills or fever, indigestion, loss of appetite, constipation, bruising, bleeding, swelling (oedema), weight loss, muscle aches, painful joints, back pain, decreased or loss of feeling or sensation such as numbness, especially in the skin, abnormal feeling or sensation such as tingling and ‘pins and needles', sleeplessness, depression, confusion, nervousness, dry mouth, loss of memory, breathlessness, nosebleed, serious lung infection with fever, shortness of breath, cough, phlegm; hair loss, skin itching or discolouration, impotence, chest pain, reduction in blood platelets, which increases the risk of bleeding or bruising (thrombocytopenia), accumulation of fluid around the lungs or an increase in liver enzymes.
Danish: En følelse af svaghed eller utilpashed, forhøjet blodtryk, uregelmæssigt hjerteslag, besvimelse, kuldegysninger eller feber, fordøjelsesbesvær, manglende appetit, forstoppelse, blå mærker, blødning, hævelse (ødem), vægttab, muskelsmerter, smerter i led, rygsmerter, nedsat eller manglende følesans, såsom følelsesløshed, især i huden, unormal følesans eller stikkende og prikkende fornemmelser, søvnløshed, depression, forvirring, nervøsitet, tør mund, hukommelsestab, stakåndethed, næseblod, alvorlig lungeinfektion med feber, åndenød, hoste, slim, hårtab, hudkløe eller misfarvning af huden, impotens, brystsmerter, nedsat antal blodplader, hvilket øger risikoen for blødning eller blå mærker (trombocytopeni), væskeophobning rundt om lungerne eller forhøjede leverenzymer.
English: There is limited information on the use of Xagrid in children and adolescents and therefore this medicine should be used with caution.
Danish: Der er begrænsede oplysninger om anvendelse af Xagrid hos børn og unge.
English: Bleeding gums, weight gain, severe chest pain (angina pectoris), heart muscle disease, (signs include fatigue, chest pain and palpitations), enlarged heart, accumulation of fluid around the heart, loss of coordination, difficulty in speaking, dry skin, migraine, visual disturbances or double vision, ringing in the ears, dizziness on standing up (especially when getting up from a sitting or lying position), increased need to pass water at night, pain, ‘flu-like' symptoms, sleepiness, widening of blood vessels, inflammation of the large bowel (signs include: diarrhoea, usually with blood and mucus, stomach pain, fever), inflammation of the stomach (signs include: pain, nausea, vomiting), area of abnormal density in the lung, increased creatinine level in blood tests, which may be a sign of kidney problems.
Danish: Blødende gummer, vægtforøgelse, svære brystsmerter (angina pectoris), sygdom i hjertemusklen (tegn omfatter træthed, brystsmerter og hjertebanken), forstørret hjerte, væskeophobning rundt om hjertet, koordinationstab, talevanskeligheder, tør hud, migræne, synsforstyrrelser eller dobbeltsyn, ringen for ørerne, svimmelhed, når De står op (især når De rejser dem fra siddende eller liggende stilling), øget vandladningstrang om natten, smerte, 'influenzalignende' symptomer, søvnighed, udvidelse af blodkarrene, tyktarmsbetændelse (tegn omfatter: diare, normalt med blod og slim, mavesmerter, feber), betændelseslignende reaktion (inflammation) i maven (tegn omfatter smerter, kvalme, opkastning), områder med unormal tæthed af lungevæv, forhøjet kreatinin i blodprøver, hvilket kan være tegn på nyreproblemer.
English: Povidone (E1201) Lactose, anhydrous Lactose monohydrate Cellulose, microcrystalline (E460) Crospovidone
Danish: Lactosemonohydrat Cellulose, mikrokrystallinsk (E460) Crospovidon
English: If you are not sure, speak to your doctor or pharmacist for advice.
Danish: Er De i tvivl, så spørg lægen eller apotekspersonalet.
English: The no observed effect level (NOEL) for male dogs (0.3mg/kg/day) corresponds to 0.1, 0.1, and 1.6-fold the AUC in humans for anagrelide at 2mg/day, and the metabolites BCH24426 and RL603, respectively.
Danish: AUC ved niveauet for ingen observeret virkning (no observed effect level, NOEL) hos hanhunde (0,3 mg/kg/dag) svarer til hhv. 0,1, 0,1 og 1,6 gange AUC for anagrelid 2 mg/dag og for metabolitterne BCH24426 og RL603 hos mennesker.
English: Uncommon: Heart failure (signs include shortness of breath, chest pain, swelling of the legs due to fluid build-up), severe problem with the rate or rhythm of the heart beat (ventricular tachycardia, supraventricular tachycardia or atrial fibrillation), inflammation of the pancreas which causes severe abdominal and back pain (pancreatitis), vomiting blood or passing bloody or black stools, severe reduction in blood cells which can cause weakness, bruising, bleeding or infections (pancytopenia), pulmonary hypertension (signs include shortness of breath, swelling in legs or ankles, and lips and skin can turn bluish colour) .
Danish: Ikke almindelig: Hjertesvigt (tegn omfatter stakåndethed, brystsmerter, hævede ben på grund af væskeophobning), svære problemer med hjerteslagets frekvens eller rytme (ventrikulær takykardi, supraventrikulær takykardi eller atrieflimmer), betændelse i bugspytkirtlen, hvilket forårsager svære mave- og rygsmerter (pankreatitis), opkastning af blod eller blodig eller sort afføring, svært nedsat antal blodlegemer, hvilket kan forårsage svaghed, blå mærker, blødning eller infektioner (pancytopeni), forhøjet blodtryk i lungerne (pulmonal hypertension, tegn omfatter stakåndethed, hævede ben eller ankler og blålige læber og hud).
English: Dizziness, tiredness, rapid heart beat, irregular or strong heartbeat (palpitations), feeling sick (nausea), diarrhoea, stomach pain, wind, being sick (vomiting), reduction in red blood cell count (anaemia), fluid retention or rash.
Danish: Svimmelhed, træthed, hurtigt hjerteslag, uregelmæssige eller kraftige hjerteslag (hjertebanken), kvalme, diare, mavesmerter, luft i maven, opkastning, nedsat antal røde blodceller (anæmi)), væske i kroppen eller udslæt.
English: Flu-like syndrome Pain
Danish: Influenzalignend e symptomer Smerte
English: At the NOEL dose (30mg/kg/day), the AUCs for anagrelide and the metabolites BCH24426 and RL603 were 425-, 31- and 13-fold higher than the AUC in humans administered an oral dose of anagrelide 2 mg/day, respectively.
Danish: Ved NOEL-dosis (30 mg/kg/dag) var AUC for anagrelid og metabolitterne BCH24426 og RL603 hhv. 425, 31 og 13 gange højere end AUC hos mennesker, der fik administreret en oral dosis anagrelid på 2 mg/dag.
English: In male rats, anagrelide at oral doses up to 240 mg/kg/day (>1000 times a 2mg/day dose, based on body surface area) was found to have no effect on fertility and reproductive performance.
Danish: Der blev ikke set nogen indvirkning på fertilitet og reproduktionsevne hos hanrotter, der fik anagrelid i orale doser på op til 240 mg/kg/dag (> 1.000 gange større end en dosis på 2 mg/dag, baseret på legemsoverfladeareal).
English: Dizziness has been reported by some patients taking Xagrid.
Danish: Nogle patienter i behandling med Xagrid, har rapporteret om svimmelhed.
English: If you notice any of these side effects, contact your doctor immediately.
Danish: Kontakt straks Deres læge, hvis De bemærker nogle af disse bivirkninger.
English: At the NOEL dose (3mg/kg/day), the AUCs for anagrelide and the metabolites BCH24426 and RL603 were 14, 2 and 2-fold higher than the AUC in humans administered an oral dose of anagrelide 2mg/day.
Danish: Ved NOEL-dosis (3 mg/kg/dag) var AUC for anagrelid og metabolitterne BCH24426 og RL603 hhv. 14, 2 og 2 gange større end AUC hos mennesker, der fik administreret en oral dosis anagrelid på 2 mg/dag.
English: The NOEL (10mg/kg/day) to this effect was 143, 12 and 11-fold higher than the AUC in humans administered a dose of anagrelide 2 mg/day, and the metabolites BCH24426 and RL603, respectively.
Danish: 10 mg/kg/dag) for denne indvirkning var hhv. 143, 12 og 11 gange højere end AUC for anagrelid 2 mg/dag og for metabolitterne BCH24426 og RL603 hos mennesker.
English: Each capsule contains 0.5 mg anagrelide (as anagrelide hydrochloride).
Danish: Hver kapsel indeholder 0,5 mg anagrelid (som anagrelidhydroklorid).
English: One hard capsule contains 0.5 mg anagrelide (as anagrelide hydrochloride).
Danish: En hård kapsel indeholder 0,5 mg anagrelid (som anagrelidhydrochlorid).
English: The observed pharmacokinetic differences between elderly and young patients with ET (see section 5.2) do not warrant using a different starting regimen or different dose titration step to achieve an individual patient-optimised anagrelide regimen.
Danish: 5.2) giver ikke grund til at anvende et forskelligt start-regimen eller forskellige dosistitreringstrin for at opnå et behandlingsregimen med anagrelid, der er optimalt for den enkelte patient.
English: Each hard capsule contains 0.5 mg anagrelide (as anagrelide hydrochloride).
Danish: Hver hård kapsel indeholder 0,5 mg anagrelid (som anagrelidhydrochlorid).
English: In combination with acetylsalicylic acid (a substance present in many medicines used to relieve pain and lower fever, as well as to prevent blood clotting, also known as aspirin), there is an increased risk of major haemorrhages (bleeding) (see section “Other medicines and Xagrid”).
Danish: I kombination med acetylsalicylsyre (et stof, der findes i mange former for medicin og anvendes til smertelindring og febernedsættelse samt til at forhindre blodet i at størkne.