FrancophonIA/ELRC3.0 huggingface dataset:
English: For dosing recommendations in this case, see section 4.2.
Lithuanian: Šiais atvejais dozavimo rekomendacijas žr. 4.2 skyriuje.
English: It may be necessary to change the dose, to take other precautions, or in some cases to stop taking one of the medicines.
Lithuanian: Gali prireikti pakeisti doz ar imtis kit atsargumo priemoni , ar kai kuriais atvejais nutraukti vieno iš vaist vartojim .
English: Functional renal maturation is an ongoing process within the first year of life in humans.
Lithuanian: Funkcinis inkst brendimas yra pirmaisiais žmoni gyvenimo metais vykstantis procesas.
English: This applies to both prescription and non-prescription medicines, especially:
Lithuanian: Tai tinka tiek vaistams, kurie parduodami pateikus recept , tiek nereceptiniams vaistams, tai yra:
English: A causal relationship to Diovan has not been established.
Lithuanian: Priežastinis ryšys su Diovan vartojimu nenustatytas.
English: • if you have recently undergone kidney transplantation (received a new kidney).
Lithuanian: • jeigu Jums neseniai atlikta inksto transplantacija (persodintas naujas inkstas);
English: • if you are taking medicines that increase the amount of potassium in your blood.
Lithuanian: • jeigu vartojate vaistus, kurie didina kalio kiek kraujyje.
English: This may cause allergic reactions possibly occuring some time after you take the solution.
Lithuanian: Ši medžiaga gali sukelti alergini reakcij , kurios gali pasireikšti pra jus kuriam laikui po tirpalo vartojimo.
English: Important information about some of the ingredients of Diovan solution
Lithuanian: Svarbi informacija apie kai kurias pagalbines Diovan tirpalo medžiagas
English: Driving and using machines
Lithuanian: Vairavimas ir mechanizm valdymas
English: For example, if the prescribed dose is 13 ml, it will be necessary to measure out the solution in three separate stages: 5 ml + 5 ml + 3 ml.
Lithuanian: Pavyzdžiui, jei Jums paskirta 13 ml doz , tirpalo reik s atmatuoti trimis atskirais etapais: 5 ml + 5 ml + 3 ml.
English: No children below the age of 1 year were enrolled in these studies.
Lithuanian: Jaunesni kaip 1 met vaikai šiuos tyrimus traukti nebuvo.
English: Pharmacotherapeutic group: Angiotensin II Antagonists, plain, ATC code: C09CA03
Lithuanian: Farmakoterapin grup - angiotenzino II antagonistai, gryni, ATC kodas - C09CA03
English: • The oral syringe fits into the bottle adapter and is used to measure out the required amount of medicine from the bottle.
Lithuanian: • Geriamasis švirkštas sistato buteliuko adapter ir yra naudojamas reikiamam vaisto kiekiui iš buteliuko atmatuoti.
English: Method of administration Diovan may be taken independently of a meal.
Lithuanian: Vartojimo metodas Diovan galima vartoti nepriklausomai nuo valgio.
English: During repeated dosing, the antihypertensive effect is substantially present within 2 weeks, and maximal effects are attained within 4 weeks and persist during long-term therapy.
Lithuanian: Vartojant pakartotin vaist doz , antihipertenzinis poveikis iš esm s pasiekiamas per 2 savaites, o stipriausias poveikis pasiekiamas per 4 savaites ir išlieka ilgalaikio gydymo metu.
English: If you get any of these, see a doctor immediately.
Lithuanian: Jei Jums pasireišk kuris nors iš ši reiškini , nedelsdami kreipkit s gydytoj .
English: Biotransformation:
Lithuanian: Biologin transformacija
English: Do not take a double dose to make up for a forgotten dose.
Lithuanian: Negalima vartoti dvigubos doz s norint kompensuoti praleist doz .
English: - Hypersensitivity to the active substance or to any of the excipients.
Lithuanian: - Padid j s jautrumas veikliajai arba bet kuriai pagalbinei medžiagai.
English: This period coincides with 36 weeks of gestation in humans, which could occasionally extend up to 44 weeks after conception in humans.
Lithuanian: Šis laikotarpis atitinka 36 moters n štumo savaites, ta iau kartais gali atitikti ir laikotarp iki 44 savait s po pastojimo.
English: - Post-myocardial infarction and/or heart failure (studied in adult patients only)
Lithuanian: - Po miokardo infarkto ir (arba) esant širdies nepakankamumui (tyrimai atlikti tik su suaugusiaisiais pacientais)
English: • if you have severe heart disease, your doctor may check your kidney function.
Lithuanian: • jeigu sergate sunkia širdies liga, tuomet gydytojas gali tikrinti J s inkst veikl ;
English: 6.5 Nature and contents of container
Lithuanian: 6.5 Pakuot ir jos turinys
English: Children less than 6 years of age
Lithuanian: Jaunesni kaip 6 met vaikai
English: National Road No. 1 (12th Km)
Lithuanian: 1 (12th Km)
English: Because of these inconsistencies, valsartan is not recommended in this age group (see section 4.8).
Lithuanian: Atsižvelgiant tokius nenuoseklius duomenis, valsartano tokio amžiaus pacientams vartoti nerekomenduojama (žr. 4.8 skyri ).
English: • Submit a Risk Management Plan (or its update) for Diovan at National level, taking into account the new paediatric data and the CHMP recommendations.
Lithuanian: • pateikti preparato Diovan rizikos valdymo plan (arba atnaujint jo variant ) nacionaliniu lygmeniu, kuriame b t atsižvelgta naujus vaik tyrim duomenis ir Žmon ms skirt vaistini preparat komiteto (CHMP) rekomendacijas.
English: The National Health Authorities shall ensure the following conditions are fulfilled by the Marketing Authorisation Holder:
Lithuanian: Nacionalin s sveikatos prieži ros institucijos užtikrina, kad rinkodaros teis s tur tojas vykdyt šias s lygas:
English: Nervous system disorders Common
Lithuanian: Nerv sistemos sutrikimai Dažni
English: You can take Diovan with or without food.
Lithuanian: Diovan galima vartoti su maistu arba be jo.
English: Valsartan is an orally active, potent, and specific angiotensin II (Ang II) receptor antagonist.
Lithuanian: Valsartanas veikia išgertas, tai stiprus, specifinis angiotenzino II (Ang II) receptori antagonistas.
English: Overall, the dose-dependent antihypertensive effect of valsartan was consistent across all the demographic subgroups.
Lithuanian: Apskritai nuo doz s priklausomas antihipertenzinis valsartano poveikis buvo panašus visuose demografiniuose pogrupiuose.
English: 4.1 Therapeutic indications
Lithuanian: 4.1 Terapin s indikacijos
English: Your doctor will normally advise you to stop taking Diovan before you become pregnant or as soon as you know you are pregnant, and will advise you to take another medicine instead of Diovan.
Lithuanian: Gydytojas patars nutraukti Diovan vartojim prieš pastojim arba tuoj pat, kai sužinosite, kad pastojote, jis patars vietoj Diovan vartoti kitus vaistus.
English: Side effects in children and adolescents are similar to those seen in adults.
Lithuanian: Vaikams ir paaugliams pasireiškiantis šalutinis poveikis b na panašus atsirandant suaugusiesiems žmon ms.
English: • lithium, a medicine used to treat some types of psychiatric illness.
Lithuanian: • li io preparatai, vaistai naudojami kai kurioms psichikos ligoms gydyti.
English: Adverse reactions are ranked by frequency, the most frequent first, using the following convention: very common ( 1/10); common ( 1/100 to <1/10); uncommon ( 1/1,000 to <1/100); rare ( 1/10,000 to <1/1,000) very rare (<1/10,000), including isolated reports.
Lithuanian: Nepageidaujamos reakcijos išd stytos pagal dažn , pirmiausia - dažniausiai pasitaikan ios, pagal toki tvark : labai dažnos ( 1/10), dažnos (nuo 1/100 iki < 1/10), nedažnos (nuo 1/1 000 iki < 1/100), retios(nuo 1/10 000 iki < 1/1 000), labai retos (< 1/10 000), skaitant pavienius atvejus.
English: However safety and efficacy of Diovan in children aged 1 to 6 years have not been established.
Lithuanian: Vis d lto Diovan saugumas ir veiksmingumas 1-6 met vaikams nenustatytas.
English: Note: You may not be able to push the bottle adapter down fully but this does not matter as it will be forced into the bottle when you screw the cap back on.
Lithuanian: Pastaba: J s galite nesugeb ti spausti buteliuko adapterio iki galo, ta iau d l to nesijaudinkite, kadangi jis bus spaustas buteliuk, kai užsuksite dangtel.
English: Hypotension, Orthostatic hypotension
Lithuanian: Hipotenzija, ortostatin hipotenzija
English: Before you measure your dose you need to get rid of any large bubbles that may be trapped in the oral syringe.
Lithuanian: Prieš matuodami Jums paskirt doz , J s turite pašalinti bet kokius didelius burbuliukus, kurie gali susidaryti geriamajame švirkšte.
English: Note: The total amount of solution that can be measured into the oral syringe is 5 ml.
Lithuanian: Pastaba: Didžiausias tirpalo kiekis, kur galima traukti geriam j švirkšt , yra 5 ml.
English: INSTRUCTIONS FOR USING THE ORAL SYRINGE AND THE DOSING CUP Please read these instructions carefully before taking the medicine.
Lithuanian: INSTRUKCIJOS KAIP NAUDOTI GERIAM J ŠVIRKŠT IR DOZAVIMO TAUREL Prieš vartojant vaisto prašytume atidžiai perskaityti šias instrukcijas.
English: • swollen face, lips, tongue or throat
Lithuanian: • veido, l p , liežuvio ar rykl s tinimas;
English: In drug interaction studies with valsartan, no interactions of clinical significance have been found with valsartan or any of the following substances: cimetidine, warfarin, furosemide, digoxin, atenolol, indometacin, hydrochlorothiazide, amlodipine, glibenclamide.
Lithuanian: Vaist tarpusavio s veikos tyrim metu nepasteb ta kliniškai reikšmingos valsartano ar kurio nors iš ši medžiag s veikos: cimetidino, varfarino, furozemido, digoksino, atenololio, indometacino, hidrochlorotiazido, amlodipino, glibenklamido.
English: Syncope, Headache
Lithuanian: Sinkop , galvos skausmas
English: The dose of valsartan should not exceed 80 mg in these patients.
Lithuanian: Tokiems ligoniams valsartano doz turi neviršyti 80 mg.
English: Since there is no effect on ACE and no potentiation of bradykinin or substance P, angiotensin II antagonists are unlikely to be associated with coughing.
Lithuanian: Kadangi n ra veikiamas AKF ir nesustiprinamas bradikinino ir substancijos P poveikis, angiotenzino II antagonistai nesukelia kosulio.
English: The rats in the juvenile valsartan study were dosed up to day 70, and effects on renal maturation (postnatal 4-6 weeks) cannot be excluded.
Lithuanian: Tyrimo metu valsartano jauniems žiurkiukams girdyta ne ilgiau kaip iki 70 gyvenimo dienos, poveikio inkst brendimui (4-6 postnatalin savait ) atmesti negalima.
English: ANNEX II AMENDMENTS TO SUMMARY OF PRODUCT CHARACTERISTICS AND PACKAGE LEAFLET
Lithuanian: II PRIEDAS PREPARATO CHARAKTERISTIK SANTRAUKOS IR PAKUOT S LAPELIO PAKEITIMAI
English: The half-life of valsartan is 6 hours.
Lithuanian: valsartano pusin s eliminacijos laikas yra 6 valandos.
English: People with high blood pressure often do not notice any signs of this problem.
Lithuanian: Pacientai, kuri kraujosp dis didelis, dažnai šios ligos simptom nejau ia.
English: The antihypertensive effect persists over 24 hours after dosing.
Lithuanian: Antihipertenzinis poveikis po vaisto vartojimo išlieka 24 val.
English: Remove the cap from the bottle by pushing it down firmly and turning it anti-clockwise (as shown on the top of the cap).
Lithuanian: Nuimkite buteliuko dangtel , stipriai spausdami j žemyn ir sukdami prieš laikrodžio rodykl (kaip parodyta ant dangtelio viršaus).
English: A bottle containing the medicine:
Lithuanian: Buteliukas, kuriame yra vaisto:
English: • Medicines should not be disposed of via wastewater or household waste.
Lithuanian: • Vaist negalima išpilti kanalizacij arba išmesti kartu su buitin mis atliekomis.
English: Therefore, monitoring of renal function at the beginning of the treatment is recommended, as well as adequate hydration of the patient.
Lithuanian: Tod l gydymo pradžioje rekomenduojama sekti inkst funkcij, o taip pat pacientui skirti pakankamai skysi.
English: Please read the instructions at the end of this leaflet before you use the oral syringe or the dosing cup.
Lithuanian: Prašytume perskaityti šio pakuot s lapelio pabaigoje pateiktas instrukcijas prieš pradedant naudoti geriam j švirkšt ar dozavimo taurel .
English: The purpose of the study was to determine the optimal dose of valsartan for reducing UAE in hypertensive patients with type 2 diabetes.
Lithuanian: Tyrimo tikslas buvo nustatyti optimali valsartano doz , kuri skiriant hipertenzija ir 2 tipo diabetu sergantiems pacientams sumaž t AIŠ.
English: common: affects 1 to 10 users in 100 uncommon: affects 1 to 10 users in 1,000 rare: affects 1 to 10 users in 10,000 very rare: affects less than 1 user in 10,000 not known: frequency cannot be estimated from the available data.
Lithuanian: Šis šalutinis poveikis gali pasireikšti tam tikru dažnumu, kuris apibr žiamas taip: labai dažnai: paveikia daugiau kaip 1 vartotoj iš 10; dažnai: paveikia nuo 1 iki 10 vartotoj iš 100; nedažnai: paveikia nuo 1 iki 10 vartotoj iš 1 000; retai: paveikia nuo 1 iki 10 vartotoj iš 10 000; labai retai: paveikia mažiau kaip 1 vartotoj iš 10 000; dažnis nežinomas: (negali b ti vertintas pagal turimus duomenis).
English: Find the marker on the oral syringe that corresponds to the required amount of medicine.
Lithuanian: Raskite geriamojo švirkšto atžym , kuri atitinka reikiam vaisto kiek .
English: The applicant will initiate a scientific dialogue via the CHMP's Scientific Advice with the involvement of the PDCO for protocol assistance with the aim of gaining further insight on a hypertensive clinical trial in younger children with valsartan and to define objectives and design parameters in investigating the efficacy in this population.
Lithuanian: Pareišk jas prad s mokslin dialog , tarpininkaujant CHMP mokslini konsultacij grupei ir dalyvaujant PDCO d l pagalbos rengiant protokol , siekdamas surinkti daugiau informacijos apie hipertenzija sergan i jaunesnio amžiaus vaik klinikin tyrim , juos gydant valsartanu, ir nustatyti tikslus bei numatyti parametrus, tiriant preparato veiksmingum šiai populiacijai.
English: Each ml solution contains 0.3 g sucrose, 1.62 mg methyl parahydroxybenzoate (E218) and 5 mg poloxamer (188)
Lithuanian: Kiekviename tirpalo mililitre yra 0,3 g sacharoz s, 1,62 mg metilo parahidroksibenzoato (E218) ir 5 mg poloksamero (188).
English: Patients with primary hyperaldosteronism should not be treated with Diovan as their renin-angiotensin system is not activated.
Lithuanian: Pacient , kuriems yra pirminis hiperaldosteronizmas, preparatu Diovan gydyti negalima, kadangi j renino ir angiotenzino sistema neaktyvuojama.
English: The study report will be finalized by the first quarter of 2014.
Lithuanian: Galutin tyrimo ataskaita bus parengta iki 2014 m.
English: 4.7 Effects on ability to drive and use machines
Lithuanian: 4.7 Poveikis geb jimui vairuoti ir valdyti mechanizmus
English: Artificial blueberry flavour (538926 C) Propylene glycol (E1520) Sodium hydroxide
Lithuanian: Dirbtinio vaivor skonio medžiaga (538926 C) Propilenglikolis (E1520) Natrio hidroksidas
English: • Do this after each time that you use the oral syringe.
Lithuanian: • Tai darykite kiekvien kart panaudoj geriam j švirkšt .
English: Luxembourg
Lithuanian: Luksemburgas
English: In the first study, the efficacy of valsartan was confirmed compared to placebo but a dose-response could not be demonstrated.
Lithuanian: Pirmojo tyrimo metu valsartano veiksmingumas, palyginti su placebo, buvo patvirtintas, ta iau nuo doz s priklausomos reakcijos nenustatyta.
English: Combined with hydrochlorothiazide, a significant additional reduction in blood pressure is achieved.
Lithuanian: Vartojant kartu su hidrochlorotiazidu, kraujosp dis dar labiau reikšmingai sumaž ja.
English: For a full list of excipients, see section 6.1.
Lithuanian: Visos pagalbin s medžiagos išvardytos 6.1 skyriuje.
English: Slowly pull the plunger out until the top edge of the black ring inside is exactly level with the marker.
Lithuanian: L tai ištraukite st mokl , kol viduje esan io juodo žiedo viršutinis kraštas tiksliai susilygins su reikiama atžyma.
English: • muscle spasms, abnormal heart rhythm (signs of hyperkalaemia)
Lithuanian: • raumen spazmai, nenormalus širdies ritmas (hiperkalemijos požymiai);
English: Kidney transplantation
Lithuanian: Inkst transplantacija
English: Paediatric heart failure and recent myocardial infarction Diovan is not recommended for the treatment of heart failure or recent myocardial infarction in children and adolescents below the age of 18 years due to the lack of data on safety and efficacy.
Lithuanian: Vaikai ir paaugliai, sergantys širdies nepakankamumu ar neseniai ištikti miokardo infarkto Diovan nerekomenduojama gydyti širdies nepakankamum ar neseniai ištikus miokardo infarkt vaikams ir jaunesniems kaip 18 met paaugliams, nes duomen apie saugum ir veiksmingum n ra.
English: poloxamer (188), citric acid anhydrous, sodium citrate, artificial blueberry flavour, propylene glycol (E1520), sodium hydroxide, hydrochloric acid, purified water.
Lithuanian: poloksameras (188), bevanden citrin r gštis, natrio citratas, dirbtinio vaivor skonio medžiaga, propilenglikolis (E1520), natrio hidroksidas, vandenilio chlorido r gštis, išgrynintas vanduo.
English: Other conditions with stimulation of the renin-angiotensin system In patients whose renal function may depend on the activity of the renin-angiotensin system (e.g patients with severe congestive heart failure), treatment with angiotensin converting enzyme inhibitors has been associated with oliguria and/or progressive azotaemia and in rare cases with acute renal failure and/or death.
Lithuanian: Kitos b kl s, kurioms esant stimuliuojama renino-angiotenzino sistema Pacient , kuri inkst funkcija gali priklausyti nuo renino-angiotenzino sistemos aktyvumo (pvz., pacient , sergan i sunkiu staziniu širdies nepakankamumu), gydymas angiotenzin konvertuojan io fermento inhibitoriais buvo susij s su oligurija ir (arba) progresuojan ia azotemija, retais atvejais - su miniu inkst nepakankamumu ir (arba) mirtimi.
English: Children and adolescents 6 to 18 years of age
Lithuanian: 6-18 met vaikai ir paaugliai
English: A long term study in the younger age group (1 to 5 years old).
Lithuanian: ketvirtojo ketvir io; ilgalaikis jaunesnio amžiaus vaik (nuo 1 iki 5 met ) grup s tyrimas.
English: • angioedema (see section “Some symptoms need immediate medical attention”)
Lithuanian: poskyr ,,Kai kurie simptomai, kuriems pasireiškus reikia skubios medicinos pagalbos“);
English: The incidence of ADRs did not appear to be related to dose or treatment duration and also showed no association with gender, age or race.
Lithuanian: NR dažnis nepriklaus nuo doz s dydžio ar gydymo trukm s, o taip pat nebuvo pasteb ta s saj su paciento lytimi, amžiumi ar rase.
English: It may be necessary to check the amount of potassium in your blood at regular intervals.
Lithuanian: Gali prireikti reguliariai tikrinti kalio kiek kraujyje;
English: Diovan works by blocking the effect of angiotensin II.
Lithuanian: Diovan blokuoja angiotenzino II sukelt poveik .
English: If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Lithuanian: Jeigu pasireišk sunkus šalutinis poveikis arba pasteb jote šiame lapelyje nenurodyt šalutin poveik , pasakykite gydytojui arba vaistininkui.
English: Metabolism and nutrition disorders Not known
Lithuanian: Metabolizmo ir mitybos sutrikimai Nežinoma
English: • that can be used if the prescribed dose requires filling the syringe several times.
Lithuanian: • J galima naudoti, jei vaisto švirkšt reikia traukti kelis kartus norint gauti paskirt doz .
English: Concomitant use not recommended
Lithuanian: Nerekomenduojama vartoti kartu
English: Immune system disorders Not known
Lithuanian: Imunin s sistemos sutrikimai Nežinoma
English: At 24 weeks, UAE was reduced (p<0.001) by 42% (-24.2 µg/min; 95% CI: -40.4 to -19.1) with valsartan and approximately 3% (-1.7 µg/min; 95% CI: -5.6 to 14.9) with amlodipine despite similar rates of blood pressure reduction in both groups.
Lithuanian: Per 24 savaites AIŠ sumaž jo (p < 0,001) 42% (-24,2 µg/min; 95 % PI: nuo -40,4 iki -19,1) skiriant valsartan ir apie 3 % (-1,7 µg/min; 95 % PI: nuo -5,6 iki 14,9) skiriant amlodipin , nepaisant panašaus kraujosp džio rodikli sumaž jimo abejose grup se.
English: • certain type of pain killers called non-steroidal anti-inflammatory medicines (NSAIDs).
Lithuanian: • kai kurie skausm malšinantys vaistai, taip vadinamieji nesteroidiniai vaistai nuo uždegimo
English: The use of Angiotensin II Receptor Antagonists (AIIRAs) is not recommended during the first trimester of pregnancy (see section 4.4).
Lithuanian: Angiotenzino II receptori antagonistus (AIIRA) pirmojo n štumo trimestro metu vartoti nerekomenduojama (žr. 4.4 skyri ).
English: Diabetes
Lithuanian: Diabetas
English: What Diovan looks like and contents of the pack Diovan 3 mg/ml oral solution is a clear, colourless to pale yellow solution.
Lithuanian: Diovan išvaizda ir kiekis pakuot je Diovan 3 mg/ml geriamasis tirpalas yra skaidrus, bespalvis ar šviesiai gelsvas tirpalas.
English: As valsartan is an angiotensin II antagonist, it cannot be excluded that the use of Diovan may be associated with impairment of the renal function.
Lithuanian: Kadangi valsartanas yra angiotenzino II antagonistas, atmesti galimyb s, kad Diovan vartojimo metu pasireikš inkst funkcijos sutrikimas, negalima.
English: The steady-state volume of distribution of valsartan after intravenous administration is about 17 litres, indicating that valsartan does not distribute into tissues extensively.
Lithuanian: Valsartano pasiskirstymo t ris po jo injekcijos ven tuo metu, kai koncentracija pusiausvyrin , yra maždaug 17 litr , tai rodo, kad nedaug valsartano pasiskirsto audinius.
English: Indirect comparisons suggest that, the oral bioavailability of valsartan with the solution is approximately 2-fold higher than the tablets.
Lithuanian: Netiesioginio palyginimo duomenys rodo, kad tirpalo sud tyje esan io geriamojo valsartano biologinis prieinamumas yra maždaug 2 kartus didesnis, lyginant su esan iu tablet se.
English: Diovan oral solution contains methyl parahydroxybenzoate which may cause allergic reactions (possibly delayed).
Lithuanian: Diovan geriamojo tirpalo sud tyje yra metilo parahidroksibenzoato, galin io sukelti alergini reakcij , kurios gali b ti uždelstos.
English: United Kingdom
Lithuanian: Didžioji Britanija
English: If you forget to take Diovan
Lithuanian: Pamiršus pavartoti Diovan
English: Treatment of hypertension in children and adolescents 6 to 18 years of age.
Lithuanian: Hipertenzijos gydymas 6-18 met vaikams ir paaugliams.
English: It acts selectively on the AT1 receptor subtype, which is responsible for the known actions of angiotensin II.
Lithuanian: Jis selektyviai veikia AT1 tipo receptorius, nuo kuri priklauso angiotenzino II sukeliamas poveikis.
English: How much to take
Lithuanian: Kiek preparato vartoti
English: Mean absolute bioavailability is 23% and 39% with tablets and solution formulation, respectively.
Lithuanian: Vidutinis biologinis table i ir tirpalo prieinamumas yra atitinkamai 23 % ir 39 %.
English: • muscle pain (myalgia)
Lithuanian: • raumen skausmai (mialgija);
English: When driving vehicles or operating machines it should be taken into account that occasionally dizziness or weariness may occur.
Lithuanian: Vairuojant transporto priemones ir valdant mechanizmus negalima pamiršti, kad Diovan gali sukelti galvos svaigim ir nuovarg .
English: At the end of 2 weeks, valsartan reduced both systolic and diastolic blood pressure in a dose-dependent manner.
Lithuanian: 2 savait s pabaigoje valsartanas sumažino ir sistolin , ir diastolin kraujosp d , poveikis priklaus nuo doz s.
English: • Do not use Diovan after the expiry date which is stated on the pack.
Lithuanian: • Ant pakuot s nurodytam tinkamumo laikui pasibaigus, Diovan vartoti negalima.
English: A press in bottle adapter:
Lithuanian: K J s naudosite buteliuk statomas adapteris:
English: Valsartan does not exhibit any partial agonist activity at the AT1 receptor and has much (about 20,000 fold) greater affinity for the AT1 receptor than for the AT2 receptor.
Lithuanian: Dalinis agonistinis poveikis AT1 receptoriams valsartanui neb dingas, AT1 receptoriams jo trauka yra daug (maždaug 20 000 kart ) didesn negu AT2 receptoriams.
English: Caution required with concomitant use
Lithuanian: Atsargumas vartojant preparatus vienu metu