FrancophonIA/ELRC3.0 huggingface dataset:
English: The pharmacokinetics of darunavir in combination with ritonavir taken twice daily in 74 treatment-experienced paediatric patients, aged 6 to 17 years and weighing at least 20 kg, showed that the administered weight-based doses of PREZISTA/ritonavir resulted in darunavir exposure comparable to that in adults receiving PREZISTA/ritonavir 600/100 mg twice daily (see section 4.2).
Croatian: Farmakokinetika darunavira u kombinaciji s ritonavirom uzetih dva puta na dan, kod 74 prethodno liječena pedijatrijska bolesnika u dobi 6 do 17 godina i težinom najmanje 20 kg, pokazala je da primjena lijeka PREZISTA/ritonavira s doziranjem ovisnim o tjelesnoj težini rezultira izloženošću darunaviru koja je usporediva s onom kod odraslih koji primaju lijek PREZISTA/ritonavir od 600/100 mg dva puta na dan (vidjeti dio 4.2).
English: Therefore, therapy with PREZISTA/cobicistat should not be initiated during pregnancy, and women who become pregnant during therapy with PREZISTA/cobicistat should be switched to an alternative regimen (see sections 4.2 and 4.6).
Croatian: Stoga se liječenje lijekom PREZISTA/kobicistat ne smije započinjati tijekom trudnoće, a žene koje zatrudne tijekom liječenja lijekom PREZISTA/kobicistat trebaju prijeći na zamjenski režim (vidjeti dijelove 4.2 i 4.6).
English: L33F, I47V, I50V, I54L or M, T74P, L76V, I84V and L89V) were present at baseline or when these mutations developed during treatment.
Croatian: V11I, V32I, L33F, I47V, I50V, I54M, I54L, T74P, L76V, I84V, L89V), dok je probir HIV-1 RNK u plazmi bio > 1000 kopija/ml.
English: PREZISTA 150 mg film-coated tablets darunavir
Croatian: PREZISTA 150 mg filmom obložene tablete darunavir
English: prezista 400 mg (this is only applicable to the outer pack)
Croatian: prezista 400 mg (odnosi se samo na vanjsko pakiranje)
English: PREZISTA is expected to increase these antineoplastic plasma concentrations.
Croatian: Očekuje se da će PREZISTA povećati koncentracije tih antineoplastika u plazmi. (CYP3A inhibicija)
English: Each milliliter contains 100 milligram of darunavir (as ethanolate).
Croatian: Jedan mililitar sadrži 100 miligrama darunavira (u obliku darunaviretanolata).
English: prezista 300 mg (this is only applicable to the outer pack)
Croatian: prezista 300 mg (odnosi se samo na vanjsko pakiranje)
English: PREZISTA 400 mg film-coated tablets
Croatian: PREZISTA 400 mg filmom obložene tablete
English: • If using the twice daily regimen: in case a dose of PREZISTA and/or ritonavir is missed within 6 hours of the time it is usually taken, patients should be instructed to take the prescribed dose of PREZISTA and ritonavir with food as soon as possible.
Croatian: U primjeni režima doziranja dva puta na dan: u slučaju kad se doza lijeka PREZISTA i/ili ritonavira propusti unutar 6 sati od uobičajenog vremena uzimanja, bolesnike se mora uputiti da propisanu dozu lijeka PREZISTA i ritonavira uzmu s hranom što je prije moguće.
English: GS-US-216-130 is a single arm, open-label, Phase III trial evaluating the pharmacokinetics, safety, tolerability, and efficacy of darunavir with cobicistat in 313 HIV-1 infected adult patients (295 treatment-naïve and 18 treatment-experienced).
Croatian: Djelotvornost darunavira od 800 mg jedanput na dan primijenjenog istodobno sa 150 mg kobicistata jedanput na dan u bolesnika prethodno neliječenih ART-om i u bolesnika prethodno liječenih ART-om GS-US-216-130 je otvoreno ispitivanje ispitivanje faze III s jednom skupinom, koje je procijenilo farmakokinetiku, sigurnost, podnošljivost i djelotvornost darunavira s kobicistatom u 313 HIVom-1 inficiranih odraslih bolesnika (295 prethodno neliječenih i 18 prethodno liječenih).
English: prezista 800 mg (this is only applicable to the outer pack)
Croatian: prezista 800 mg (odnosi se samo na vanjsko pakiranje)
English: Lovastatin and simvastatin are expected to have markedly increased plasma concentrations when co-administered with boosted PREZISTA.
Croatian: Za lovastatin i simvastatin se očekuje značajno povišenje koncentracija u plazmi kada se primjenjuju istodobno s pojačanom PREZISTOM. (inhibicija CYP3A)
English: prezista 600 mg (this is only applicable to the outer pack)
Croatian: prezista 600 mg (odnosi se samo na vanjsko pakiranje)
English: darunavir AUC24h ↑ 33% (based on population pharmacokinetic model)
Croatian: Istodobna sistemska primjena klotrimazola i pojačane PREZISTE može povisiti koncentracije darunavira i/ili klotrimazola u plazmi. darunavir AUC24h ↑ 33% (na temelju populacijskog farmakokinetičkog modela)
English: PREZISTA must always be given orally with cobicistat or low dose ritonavir as a pharmacokinetic enhancer and in combination with other antiretroviral medicinal products (see section 5.2).
Croatian: PREZISTA se uvijek mora primjenjivati peroralno s kobicistatom ili niskom dozom ritonavira kao farmakokinetičkim pojačivačem, te u kombinaciji s drugim antiretrovirusnim lijekovima. (vidjeti dio 5.2).
English: The pharmacokinetics of darunavir in combination with ritonavir taken once daily in 10 treatment-experienced paediatric patients, aged 3 to < 6 years and weighing at least 14 kg to < 20 kg, showed that weight-based dosages resulted in darunavir exposure that was comparable to that achieved in adults receiving PREZISTA/ritonavir 800/100 mg once daily (see section 4.2).
Croatian: Farmakokinetika darunavira u kombinaciji s ritonavirom uzetih jedanput na dan, kod 10 pedijatrijskih prethodno liječenih bolesnika, u dobi od 3 do < 6 godina i težine najmanje 14 kg do < 20 kg, pokazala je da je doziranje temeljeno na težini rezultiralo izloženošću darunaviru, sličnoj onoj postignutoj u odraslih koji su uzimali lijekove PREZISTA/ritonavir 800/100 mg jedanput na dan (vidjeti dio 4.2).
English: Co-administration of boosted PREZISTA with clonazepam may increase concentrations of clonazepam.
Croatian: Istovremena primjena pojačanog lijeka PREZISTA s klonazepamom može povećati koncentracije klonazepama. (CYP3A inhibicija)
English: PREZISTA 150 mg film-coated tablets EU/1/06/380/004
Croatian: PREZISTA 150 mg filmom obložene tablete EU/1/06/380/004
English: • ART-experienced with no darunavir resistance associated mutations (DRV-RAMs) and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Croatian: U bolesnika prethodno liječenih ART-om, bez mutacija povezanih s rezistencijom na darunavir DRV-RAM* a imaju plazmatsku HIV-1 RNK < 100 000 kopija/ml i broj CD4+ stanica ≥ 100 stanica x 10
English: PREZISTA 300 mg film-coated tablets
Croatian: PREZISTA 300 mg filmom obložene tablete
English: What PREZISTA looks like and contents of the pack Film-coated, light orange, oval shaped tablet, mentioning TMC on one side, 400MG on the other side.
Croatian: Svijetlonarančasta, duguljasta, filmom obložena tableta s oznakom TMC s jedne strane, a 400MG s druge strane.
English: PREZISTA/ ritonavir 600/100 mg twice daily N=296
Croatian: PREZISTA/ ritonavir 600/100 mg dva puta na dan n=296
English: - Take your other HIV medicines used in combination with PREZISTA and ritonavir as recommended by your doctor
Croatian: - Ostale lijekove protiv HIV-a koje primjenjujete istodobno s lijekom PREZISTA i ritonavirom,
English: PREZISTA/ ritonavir 800/100 mg once daily N=294
Croatian: PREZISTA/ ritonavir 800/100 mg jedanput na dan n=294
English: PREZISTA/ ritonavir 600/100 mg twice daily N=298
Croatian: PREZISTA/ ritonavir 600/100 mg dva puta na dan n=298
English: Co-administration of boosted PREZISTA with dapoxetine is contraindicated.
Croatian: Istodobna primjena pojačane PREZISTE s dapoksetinom je kontraindicirana.
English: OUTER CARTON / BOTTLE LABEL
Croatian: KUTIJA / NALJEPNICA NA BOČICI
English: Treatment-experienced darunavir/cobicistat 800/150 mg once daily N=18
Croatian: Prethodno liječeni darunavir/kobicistat 800/150 mg jedanput na dan N=18
English: PREZISTA/ritonavir 800/100 mg once daily + OBR N=294
Croatian: PREZISTA/ritonavir 800/100 mg jedanput na dan + OOR n=294
English: 100 milligram (1.2 milliliter) between 30 and 40 kilograms 675 milligram (6.8 milliliter) 100 milligram (1.2 milliliter) more than 40 kilograms
Croatian: 675 miligrama (6,8 mililitara) 100 miligrama (1,2 mililitra)
English: Each film-coated tablet contains 150 mg darunavir (as ethanolate).
Croatian: Jedna filmom obložena tableta sadrži 150 mg darunavira (u obliku darunaviretanolata).
English: PREZISTA 800 mg film-coated tablets darunavir
Croatian: PREZISTA 800 mg filmom obložene tablete darunavir
English: Do not stop taking PREZISTA without talking to your doctor first Anti-HIV medicine may make you feel better.
Croatian: Nemojte prestati uzimati lijek PREZISTA bez prethodnog razgovora s liječnikom.
English: Each tablet contains 150 milligram of darunavir (as ethanolate).
Croatian: Jedna tableta sadrži 150 miligrama darunavira (u obliku darunaviretanolata).
English: PREZISTA is expected to increase these β-blocker plasma concentrations.
Croatian: Očekuje se da će PREZISTA povećati koncentracije tih β-blokatora u plazmi. (CYP2D6 inhibicija)
English: It is not recommended to combine PREZISTA co-administered with low dose ritonavir with saquinavir.
Croatian: Ne preporučuje se istodobna primjena lijeka PREZISTA istodobno s niskom dozom ritonavira u kombinaciji sa sakvinavirom.
English: Co-administration of boosted PREZISTA and alfuzosin is contraindicated (see section 4.3).
Croatian: Istodobna primjena pojačane PREZISTE s alfuzozinom je kontraindicirana (vidjeti dio 4.3).
English: • If using the once daily regimen: in case a dose of PREZISTA and/or cobicistat or ritonavir is missed within 12 hours of the time it is usually taken, patients should be instructed to take the prescribed dose of PREZISTA and cobicistat or ritonavir with food as soon as possible.
Croatian: U primjeni režima doziranja jedanput na dan: u slučaju kad se doza lijeka PREZISTA i/ili kobicistata ili ritonavira propusti unutar 12 sati od uobičajenog vremena uzimanja, bolesnike se mora uputiti da propisanu dozu lijeka PREZISTA i kobicistata ili ritonavira uzmu s hranom što je prije moguće.
English: Concomitant use of PREZISTA co-administered with low dose ritonavir and these antidepressants may increase concentrations of the antidepressant.
Croatian: Istodobno uzimanje PREZISTE istodobno primijenjene s niskom dozom ritonavira i tih antidepresiva može povećati koncentracije antidepresiva. (CYP2D6 i/ili CYP3A inhibicija)
English: If you take PREZISTA once a day and if you notice within 12 hours, you must take the oral suspension immediately.
Croatian: Ako uzimate lijek PREZISTA jedanput na dan i primijetite da niste uzeli lijek unutar 12 sati, oralnu suspenziju morate uzeti odmah, uvijek s kobicistatom ili ritonavirom i hranom.
English: The Summary of Product Characteristics of ritonavir as appropriate, must therefore be consulted prior to initiation of therapy with PREZISTA.
Croatian: Stoga se, prije početka terapije lijekom PREZISTA, mora pročitati odgovarajući Sažetak opisa svojstava za ritonavir.
English: PREZISTA 400 mg film-coated tablets darunavir
Croatian: PREZISTA 400 mg filmom obložene tablete darunavir
English: - In the evening, take 600 milligram PREZISTA together with 100 milligram ritonavir.
Croatian: - Navečer uzmite 600 miligrama lijeka PREZISTA zajedno sa 100 miligrama ritonavira.
English: PREZISTA 600 mg film-coated tablets
Croatian: PREZISTA 600 mg filmom obložene tablete
English: PREZISTA co-administered with low dose ritonavir and nevirapine can be used without dose adjustments.
Croatian: PREZISTA istodobno primijenjena s niskom dozom ritonavira i nevirapinom može se primjeniti bez prilagodbe doze.
English: A reduction in colchicine dosage or an interruption of colchicine treatment is recommended in patients with normal renal or hepatic function if treatment with PREZISTA co-administered with low dose ritonavir is required.
Croatian: Ako je potrebno liječenje lijekom PREZISTA istodobno primjenjenog s niskom dozom ritonavira, preporučuje se smanjiti dozu kolhicina ili prekinuti liječenje kolhicinom u bolesnika s normalnom funkcijom bubrega ili jetre.
English: Each film-coated tablet contains 800 mg darunavir (as ethanolate).
Croatian: Jedna filmom obložena tableta sadrži 800 mg darunavira (u obliku darunaviretanolata).
English: When administration of rosuvastatin and boosted PREZISTA is required, it is recommended to start with the lowest possible dose of rosuvastatin and titrate up to the desired clinical effect while monitoring for safety.
Croatian: Kada je potrebno primjeniti rosuvastatin i pojačanu PREZISTU, preporučuje se početi s najnižom mogućom dozom rosuvastatina te dozu titrirati do željenog kliničkog učinka i pri tome pratiti sigurnost primjene.
English: PREZISTA is also available as 75 milligram, 150 milligram, 300 milligram, 400 milligram, 600 milligram and 800 milligram film-coated tablets.
Croatian: PREZISTA je također dostupna i u obliku filmom obloženih tableta od 75 miligrama, 150 miligrama, 300 miligrama, 400 miligrama, 600 miligrama i 800 miligrama.
English: PREZISTA co-administered with low dose ritonavir and amiodarone, bepridil, dronedarone, ivabradine, quinidine, or ranolazine is contraindicated (see section 4.3).
Croatian: Istodobna primjena lijeka PREZISTA istodobno primijenjenog s niskom dozom ritonavira i amiodarona, bepridila, dronedarona, ivabradina, kinidina ili ranolazina je kontraindicirana (vidjeti dio
English: It is not recommended to co-administer boosted PREZISTA and simeprevir.
Croatian: Ne preporučuje se istodobna primjena pojačane PREZISTE sa simeprevirom.
English: Reproductive system and breast disorders uncommon erectile dysfunction, gynaecomastia General disorders and administration site conditions common asthenia, fatigue uncommon pyrexia, chest pain, peripheral oedema, malaise, feeling hot, irritability, pain rare chills, abnormal feeling, xerosis
Croatian: Opći poremećaji i reakcije na mjestu primjene često astenija, umor manje često pireksija, bol u prsištu, periferni edem, malaksalost, osjećaj vrućine, iritabilnost, bol rijetko zimica, nenormalno osjećanje, kseroza
English: PREZISTA 600 mg film-coated tablets EU/1/06/380/002
Croatian: PREZISTA 600 mg filmom obložene tablete EU/1/06/380/002
English: You must eat a meal or a snack within 30 minutes prior to taking your PREZISTA and cobicistat or ritonavir.
Croatian: Unutar 30 minuta prije uzimanja lijeka PREZISTA i kobicistata ili ritonavira morate pojesti obrok ili nešto prigristi.
English: If a once daily dose of PREZISTA and/or cobicistat or ritonavir is missed within 12 hours of the time it is usually taken, patients should be instructed to take the prescribed dose of PREZISTA and cobicistat or ritonavir with food as soon as possible.
Croatian: U slučaju kad je doza lijeka PREZISTA i/ili kobicistata ili ritonavira koja se uzima jedanput na dan propuštena unutar 12 sati od uobičajenog vremena uzimanja, bolesnike se mora uputiti da propisanu dozu lijeka PREZISTA i kobicistata ili ritonavira uzmu s hranom što je prije moguće.
English: When administration of rosuvastatin and PREZISTA co-administered with low dose ritonavir is required, it is recommended to start with the lowest possible dose of rosuvastatin and titrate up to the desired clinical effect while monitoring for safety.
Croatian: Kada je potrebno primjeniti rosuvastatin i lijek PREZISTA primijenjen istodobno s niskom dozom ritonavira, preporučuje se početi s najnižom mogućom dozom rosuvastatina te dozu titrirati do željenog kliničkog učinka i pri tome pratiti sigurnost primjene.
English: The Summary of Product Characteristics of ritonavir must, therefore, be consulted prior to initiation of therapy with PREZISTA.
Croatian: Stoga se, prije početka terapije lijekom PREZISTA, mora pročitati Sažetak opisa svojstava lijeka za ritonavir.
English: Boosted PREZISTA is expected to increase these β-blocker plasma concentrations.
Croatian: Očekuje se da će pojačana PREZISTA povećati koncentracije tih β-blokatora u plazmi. (CYP2D6 inhibicija)
English: PREZISTA 400 mg film-coated tablets EU/1/06/380/003
Croatian: PREZISTA 400 mg filmom obložene tablete EU/1/06/380/003
English: Each tablet contains 800 milligram of darunavir (as ethanolate).
Croatian: Jedna tableta sadrži 800 miligrama darunavira (u obliku darunaviretanolata).
English: PREZISTA/ritonavir 600/100 mg twice daily + OBR N=298
Croatian: PREZISTA/ritonavir 600/100 mg dva puta na dan + OOR n=298
English: Each tablet contains 600 milligram of darunavir (as ethanolate).
Croatian: Jedna tableta sadrži 600 miligrama darunavira (u obliku darunaviretanolata).
English: PREZISTA 300 mg film-coated tablets darunavir
Croatian: PREZISTA 300 mg filmom obložene tablete darunavir
English: PREZISTA 300 mg film-coated tablets EU/1/06/380/001
Croatian: PREZISTA 300 mg filmom obložene tablete EU/1/06/380/001
English: PREZISTA/ritonavir 600/100 mg twice daily + OBR N=296
Croatian: PREZISTA/ritonavir 600/100 mg dva puta na dan + OOR n=296
English: PREZISTA 600 mg film-coated tablets darunavir
Croatian: PREZISTA 600 mg filmom obložene tablete darunavir
English: This can be seen in a blood test. - high blood pressure, flushing - red or dry eyes - fever, swelling of lower limbs due to fluids, malaise, irritability, pain - symptoms of infection, herpes simplex - erectile dysfunction, enlargement of breasts - sleeping problems, sleepiness, depression, anxiety, abnormal dreams, decrease in sexual drive
Croatian: podrigivanje - zatajenje bubrega, bubrežni kamenci, otežano mokrenje, često ili prekomjerno mokrenje, katkad i noću - koprivnjača, teško oticanje kože i drugih tkiva (najčešće usnica ili očiju), ekcem, prekomjerno znojenje, noćno znojenje, gubitak kose, akne, ljuskasta koža, obojenje noktiju - bolovi u mišićima, grčevi u mišićima ili slabost, bolovi u udovima, osteoporoza - usporavanje funkcije štitnjače, može se vidjeti iz rezultata krvnih pretraga - povišeni krvni tlak, crvenilo uz osjećaj vrućine - crvene ili suhe oči - vrućica, oticanje nogu zbog nakupljanja tekućine, opća slabost, razdražljivost, bol - simptomi infekcije, herpes simpleks - erektilna disfunkcija, povećanje dojki - teškoće sa spavanjem, pospanost, depresija, tjeskoba, abnormalni snovi, smanjeni spolni nagon.
English: If you notice within 6 hours, you must take your missed dose immediately.
Croatian: Ako primijetite da niste uzeli lijek unutar 6 sati, propuštenu dozu morate uzeti odmah, uvijek s ritonavirom i hranom.
English: Recommended dose for treatment-experienced paediatric patients (3 to 17 years) with PREZISTA tablets and ritonavir
Croatian: Preporučena doza tableta lijeka PREZISTA i ritonavira a za pedijatrijske bolesnike (od 3 do 17 godina) koji su prethodno liječeni
English: PREZISTA/ritonavir, the PREZISTA/ritonavir 600/100 mg twice daily regimen should be used (see section 4.4).
Croatian: Ako se efavirenz primjenjuje u kombinaciji s lijekom PREZISTA/ritonavir, mora se primijeniti lijek PREZISTA/ritonavir 600/100 mg u režimu doziranja dva puta na dan (vidjeti dio 4.4).
English: PREZISTA co-administered with low dose ritonavir and rilpivirine can be used without dose adjustments.
Croatian: PREZISTA istodobno primijenjena s niskom dozom ritonavira i rilpivirinom može se primjeniti bez prilagodbe doze.
English: - In the evening, take one 600 milligram PREZISTA tablet together with 100 milligram ritonavir.
Croatian: - Navečer uzmite jednu tabletu lijeka PREZISTA od 600 miligrama zajedno sa 100 miligrama ritonavira.
English: Each film-coated tablet contains 600 mg darunavir (as ethanolate).
Croatian: Jedna filmom obložena tableta sadrži 600 mg darunavira (u obliku darunaviretanolata).
English: Instructions for children 3 years of age and above, weighing more than 40 kilograms - Take 800 milligram PREZISTA (2 tablets containing 400 milligram of PREZISTA or 1 tablet containing 800 milligram of PREZISTA) at the same time, once a day, every day.
Croatian: Upute za djecu od 3 godine i više, težine najmanje 40 kilograma - Uzmite 800 miligrama lijeka PREZISTA (2 tablete koja sadrže 400 miligrama lijeka
English: Vascular disorders uncommon hypertension, flushing
Croatian: Krvožilni poremećaji manje često hipertenzija, crvenilo uz osjećaj vrućine
English: - In the morning, take one 600 milligram PREZISTA tablet together with 100 milligram ritonavir.
Croatian: - Ujutro uzmite jednu tabletu lijeka PREZISTA od 600 miligrama zajedno sa 100 miligrama ritonavira.
English: - In the morning, take 600 milligram PREZISTA together with 100 milligram ritonavir.
Croatian: - Ujutro uzmite uzmite 600 miligrama lijeka PREZISTA zajedno sa 100 miligrama ritonavira.
English: It is not recommended to co-administer PREZISTA with low dose ritonavir and simeprevir.
Croatian: Ne preporučuje se istodobna primjena PREZISTE s niskom dozom ritonavira sa simeprevirom.
English: Each tablet contains 300 milligram of darunavir (as ethanolate).
Croatian: Jedna tableta sadrži 300 miligrama darunavira (u obliku darunaviretanolata).
English: Opaque, white, high density polyethylene (HDPE) plastic, 160 ml bottle containing 240 tablets, fitted with polypropylene (PP) child resistant closure.
Croatian: Neprozirna, bijela, plastična bočica od polietilena visoke gustoće (HDPE) od 160 ml, sadrži 240 tableta i zatvorena je sigurnosnim polipropilenskim (PP) zatvaračem za djecu.
English: Opaque, white, high density polyethylene (HDPE) plastic, 160 ml bottle containing 480 tablets, fitted with polypropylene (PP) child resistant closure.
Croatian: Neprozirna, bijela, plastična bočica od polietilena visoke gustoće (HDPE) od 160 ml, sadrži 480 tableta i zatvorena je sigurnosnim polipropilenskim (PP) zatvaračem za djecu.
English: When administration of pravastatin and PREZISTA co-administered with low dose ritonavir is required, it is recommended to start with the lowest possible dose of pravastatin and titrate up to the desired clinical effect while monitoring for safety.
Croatian: Kada je potrebno primjeniti pravastatin i lijek PREZISTA primijenjen istodobno s niskom dozom ritonavira, preporučuje se početi s najnižom mogućom dozom pravastatina te dozu titrirati do željenog kliničkog učinka i pri tome pratiti sigurnost primjene.
English: Opaque, white, high density polyethylene (HDPE) plastic, 160 ml bottle containing 120 tablets, fitted with polypropylene (PP) child resistant closure.
Croatian: Neprozirna, bijela, plastična bočica od polietilena visoke gustoće (HDPE) od 160 ml, sadrži 120 tableta i zatvorena je sigurnosnim polipropilenskim (PP) zatvaračem za djecu.
English: When administration of pravastatin and boosted PREZISTA is required, it is recommended to start with the lowest possible dose of pravastatin and titrate up to the desired clinical effect while monitoring for safety.
Croatian: Kada je potrebno primjeniti pravastatin i pojačanu PREZISTU, preporučuje se početi s najnižom mogućom dozom pravastatina te dozu titrirati do željenog kliničkog učinka i pri tome pratiti sigurnost primjene.
English: HIV-1 RNA < 50 copies/ml CD4+ cell count mean change from baseline
Croatian: HIV-1 RNK < 50 kopija/ml Postotak promjene CD4+ od početne vrijednosti
English: Each tablet contains 400 milligram of darunavir (as ethanolate).
Croatian: Jedna tableta sadrži 400 miligrama darunavira (u obliku darunaviretanolata).
English: Each film-coated tablet contains 400 mg darunavir (as ethanolate).
Croatian: Jedna filmom obložena tableta sadrži 400 mg darunavira (u obliku darunaviretanolata).
English: PREZISTA is also available as 150 milligram, 300 milligram, 400 milligram, 600 milligram and 800 milligram film-coated tablets and 100 milligram per milliliter oral suspension.
Croatian: PREZISTA je također dostupna i u obliku filmom obloženih tableta od 150 miligrama, 300 miligrama, 400 miligrama, 600 miligrama i 800 miligrama te u obliku oralne suspenzije od 100 miligrama po mililitru.
English: ART-experienced paediatric patients (3 to 17 years of age and weighing at least 40 kg) The dose of cobicistat to be used with PREZISTA in children less than 18 years of age has not been established.
Croatian: Pedijatrijski bolesnici koji nisu prethodno liječeni ART-om (u dobi od 3 do 17 godina i težine najmanje 40 kg)