FrancophonIA/ELRC3.0 huggingface dataset:
English: Midazolam (2 mg single dose)/ grazoprevir (200 mg once daily)
Slovenian: Midazolam (2 mg enkratni odmerek)/grazoprevir (200 mg enkrat na dan)
English: ↔ Elbasvir AUC 1.05 (0.92, 1.18) Cmax 1.11 (0.98, 1.26) C24 1.03 (0.91, 1.17)
Slovenian: AUC 1,05 (0,92; 1,18) Cmax 1,11 (0,98; 1,26) C24 1,03 (0,91; 1,17)
English: • check for side effects
Slovenian: • da preveri ali so se morda pojavili neželeni učinki,
English: GT 1, 3 TN with or without cirrhosis TE Null Responder with or without cirrhosis TN HCV/HIV1 co-infection without cirrhosis
Slovenian: GT 1, 3 TN s cirozo ali brez nje, TE neodzivni s cirozo ali brez nje, TN okuženi s HCV/HIV brez ciroze
English: ↔ Elbasvir AUC 1.13 (0.94, 1.37) Cmax 1.07 (0.88, 1.29) C24 1.22 (1.02, 1.45)
Slovenian: AUC 1,13 (0,94; 1,37) Cmax 1,07 (0,88; 1,29) C24 1,22 (1,02; 1,45)
English: Weight/BMI
Slovenian: Telesna masa/ITM
English: ↔ Elbasvir AUC 0.93 (0.82, 1.05) Cmax 0.88 (0.77, 1.00) C24 0.92 (0.18, 1.05)
Slovenian: AUC 0,93 (0,82; 1,05) Cmax 0,88 (0,77; 1,00) C24 0,92 (0,18; 1,05)
English: ↔ Elbasvir AUC 1.05 (0.93, 1.18) Cmax 1.02 (0.92, 1.14) C24 1.03 (0.92, 1.17)
Slovenian: AUC 1,05 (0,93; 1,18) Cmax 1,02 (0,92; 1,14) C24 1,03 (0,92; 1,17)
English: (10 mg single dose)/ elbasvir (50 mg once daily) / grazoprevir (200 mg once daily)
Slovenian: (10 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: No dose adjustment of ZEPATIER is required in patients with mild hepatic impairment (Child-Pugh A).
Slovenian: Pri bolnikih z blago okvaro jeter (Child Pugh A) prilagoditev odmerka zdravila ZEPATIER ni potrebna.
English: (300 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: (300 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Subjects with baseline NS5A polymorphisms, % (n/N)
Slovenian: preiskovanci z izhodiščnimi polimorfizmi NS5A % (n/N)
English: ↔ Elbasvir AUC 0.97 (0.90, 1.06) Cmax 0.99 (0.88, 1.10) C24 0.92 (0.83, 1.02)
Slovenian: AUC 0,97 (0,90; 1,06) Cmax 0,99 (0,88; 1,10) C24 0,92 (0,83; 1,02)
English: Hepatic impairment
Slovenian: Pogosti omotica
English: ↔ Elbasvir AUC 1.17 (0.98, 1.39) Cmax 1.29 (1.06, 1.58) C24 1.21 (1.03, 1.43)
Slovenian: AUC 1,17 (0,98; 1,39) Cmax 1,29 (1,06; 1,58) C24 1,21 (1,03; 1,43)
English: ↔ Elbasvir AUC 1.07 (1.00, 1.15) Cmax 1.07 (0.99, 1.16) C24 1.04 (0.98, 1.11)
Slovenian: AUC 1,07 (1,00; 1,15) Cmax 1,07 (0,99; 1,16) C24 1,04 (0,98; 1,11)
English: • feeling dizzy
Slovenian: • občutek tesnobe
English: ↔ Elbasvir AUC 0.92 (0.75, 1.14) Cmax 0.86 (0.71, 1.04) C24 0.87 (0.70, 1.09)
Slovenian: AUC 0,92 (0,75; 1,14) Cmax 0,86 (0,71; 1,04) C24 0,87 (0,70; 1,09)
English: (600 mg twice daily)/ ritonavir (100 mg twice daily/ grazoprevir (200 mg once daily)
Slovenian: (600 mg dvakrat na dan)/ritonavir (100 mg dvakrat na dan)/grazoprevir (200 mg enkrat na dan)
English: N=65
Slovenian: 16 tednov n = 65
English: ↔ Elbasvir AUC 0.81 (0.57, 1.17) Cmax 0.89 (0.61, 1.29) C24 0.80 (0.55, 1.16)
Slovenian: AUC 0,81 (0,57; 1,17) Cmax 0,89 (0,61; 1,29) C24 0,80 (0,55; 1,16)
English: (OATP1B inhibition and CYP3A induction)
Slovenian: (zaviranje OATP1B in indukcija CYP3A)
English: Overall prevalence of GT1b-infected subjects with baseline NS5A polymorphisms in the pooled analyses was
Slovenian: V združenih analizah je bila celokupna razširjenost z genotipom 1b okuženih preiskovancev z izhodiščnimi polimorfizmi NS5A 14 % (74/540).
English: (400 mg twice daily)/ ritonavir (100 mg twice daily/ grazoprevir (200 mg once daily)
Slovenian: (400 mg dvakrat na dan)/ritonavir (100 mg dvakrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Montelukast (10 mg single dose)/ grazoprevir (200 mg single dose)
Slovenian: Montelukast (10 mg enkratni odmerek)/grazoprevir (200 mg enkrat na dan)
English: Subjects with baseline NS3 polymorphisms, % (n/N)
Slovenian: preiskovanci z izhodiščnimi polimorfizmi NS3 % (n/N)
English: (600 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: (600 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: ↔ Elbasvir AUC 1.07 (1.00, 1.14) Cmax 1.07 (0.98, 1.16) C24 1.05 (0.97, 1.14)
Slovenian: AUC 1,07 (1,00: 1,14) Cmax 1,07 (0,98; 1,16) C24 1,05 (0,97; 1,14)
English: Mycophenolate mofetil (1,000 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: Mofetilmikofenolat (1.000 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: (400 mg twice daily)/ grazoprevir (200 mg once daily)
Slovenian: (400 mg dvakrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Cirrhotic
Slovenian: S cirozo
English: ↔ Elbasvir AUC 0.98 (0.93, 1.02) Cmax 0.97 (0.89, 1.05) C24 0.97 (0.92, 1.02)
Slovenian: AUC 0,98 (0,93; 1,02) Cmax 0,97 (0,89; 1,05) C24 0,97 (0,92; 1,02)
English: KINASE INHIBITOR
Slovenian: ZAVIRALEC KINAZE sunitinib
English: Ciclosporin (400 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: Ciklosporin (400 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: ACID REDUCING AGENTS H2-receptor antagonists Famotidine (20 mg single dose)/ elbasvir (50 mg single dose)/ grazoprevir (100 mg single dose)
Slovenian: Famotidin (20 mg enkratni odmerek)/elbasvir (50 mg enkratni odmerek)/grazoprevir (100 mg enkratni odmerek)
English: ↔ Elbasvir AUC 0.98 (0.93, 1.04) Cmax 0.97 (0.89, 1.05) C24 0.98 (0.93, 1.03)
Slovenian: AUC 0,98 (0,93; 1,04) Cmax 0,97 (0,89; 1,05) C24 0,98 (0,93; 1,03)
English: Pravastatin (40 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: Pravastatin (40 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Dolutegravir (50 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: Dolutegravir (50 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Tacrolimus (2 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily)
Slovenian: Takrolimus (2 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: NS5A polymorphisms (conferring > 5-fold potency loss to elbasvir) included M28T/A, Q30E/H/R/G/K/D, L31M/V/F, H58D, and Y93C/H/N
Slovenian: polimorfizem NS5A (> 5-krat zmanjša učinkovitost elbasvirja) vključno z M28T/A, Q30E/H/R/G/K/D, L31M/V/F, H58D in Y93C/H/N V združenih analizah je bila celokupna razširjenost z genotipom 1a okuženih preiskovancev z izhodiščnimi polimorfizmi NS5A 7 % (55/825).
English: (600 mg PO single dose)/ grazoprevir (200 mg once daily)
Slovenian: (600 mg peroralni enkratni odmerek)/grazoprevir (200 mg enkrat na dan)
English: Rifampicin (600 mg IV single dose)/ elbasvir (50 mg single dose)
Slovenian: Rifampicin (600 mg enkratni odmerek i.v.
English: • muscle aches
Slovenian: • suha usta
English: Prednisone (40 mg single dose)/ elbasvir (50 mg once daily)/ grazoprevir (200 mg once daily
Slovenian: Prednizon (40 mg enkratni odmerek)/elbasvir (50 mg enkrat na dan)/grazoprevir (200 mg enkrat na dan)
English: Subjects without baseline NS3 polymorphisms, % (n/N)
Slovenian: Genotip 1b preiskovanci brez izhodiščnih polimorfizmov NS3 % (n/N)
English: Avoid contact with eyes.
Slovenian: Izogibajte se stiku z očmi.
English: A white suspension.
Slovenian: Bela suspenzija.
English: Do not store above 25 °C.
Slovenian: Ne shranjujte nad 25°C.
English: Whatever the position
Slovenian: Ne glede na položaj
English: Whatever the size
Slovenian: Ne glede na velikost
English: 4.8 Interaction with other medicinal products and other forms of interaction
Slovenian: 4.8 Interakcija z drugimi zdravili in druge oblike interakcij
English: Do not use in dogs with generalised demodecosis.
Slovenian: Ne uporabljajte pri psih z generalizirano demodikozo.
English: Special warnings:
Slovenian: Posebna opozorila :
English: [Single-dose container:]
Slovenian: [Enoodmerni vsebnik:]
English: In all cases, treatment with the veterinary medicinal product was not discontinued and all dogs recovered without any specific therapy.
Slovenian: V nobenem primeru zdravljenje z zdravilom za uporabo v veterinarski medicini ni bilo prekinjeno in vsi psi so okrevali brez posebne terapije.
English: • Take out one pipette from the box.
Slovenian: • Iz škatlice vzemite eno kapalko.
English: SPECIAL STORAGE CONDITIONS Do not store above 25 °C.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Ne shranjujte nad 25°C.
English: 1 dose / ear / day for 5 days
Slovenian: 1 odmerek / uho / dan v petih dneh
English: • To open: hold up the pipette upright and break the top of the cannula.
Slovenian: • Odpiranje: kapalko držite pokonci in prelomite vrh kanile.
English: ATCvet code: QS02CA03.
Slovenian: Oznaka ATC vet: QS02CA03
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 20/11/2008.
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum pridobitve dovoljenja za promet: 20/11/2008.
English: The veterinary medicinal product should be used at room temperature (i.e. do not instil cold product).
Slovenian: Zdravilo za uporabo v veterinarski medicini uporabljajte pri sobni temperaturi (tj. ne vkapajte hladnega zdravila).
English: Date of first renewal: 11/11/2013.
Slovenian: Datum podaljšanja dovoljenja za promet: 11/11/2013.
English: Mild to moderate redness of the ear was common (2.4% of treated dogs).
Slovenian: Pogosta je blaga do zmerna pordelost ušesa (2,4 % zdravljenih psov).
English: Interaction with other medicinal products and other forms of interaction: Compatibility with ear cleaners has not been demonstrated.
Slovenian: Interakcija z drugimi zdravili in druge oblike interakcij : Ni podatkov o združljivosti tega zdravila s čistili za ušesa.
English: Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements
Slovenian: Vsako neporabljeno zdravilo za uporabo v veterinarski medicini ali odpadne snovi, ki nastanejo iz teh zdravil, je treba odstraniti v skladu z lokalnimi zahtevami.
English: See also “Special precautions for use in animals”.
Slovenian: Glejte tudi »Posebni previdnostni ukrepi za uporabo pri živalih«..
English: All Escherichia coli isolates were fully susceptible to gentamicin.
Slovenian: Vse izolirane bakterije rodu Escherichia coli so bile v celoti dovzetne za gentamicin.
English: The diesters are transformed inside the skin structures in C17 monoesters responsible for the potency of the therapeutic class.
Slovenian: Diestri se v kožnih strukturah spremenijo v monoestre C17, odgovorne za učinkovitost terapevtske skupine.
English: Since many bacterial strains may be involved in otitis externa in dogs, the mechanisms of resistance can vary.
Slovenian: Glede na to, da so pri vnetju zunanjega sluhovoda pri psih lahko vključeni številni bakterijski sevi, se lahko obrambni mehanizmi razlikujejo.
English: It is recommended that the external ear canal should be cleaned and dried before treatment and excess hair around the treatment area be cut.
Slovenian: Priporočljivo je, da se pred zdravljenjem zunanji ušesni kanal očisti in osuši ter ostriže odvečno dlako okoli mesta zdravljenja.
English: The diesters are lipophilic components ensuring an enhanced penetration into the skin associated with low systemic bioavailability.
Slovenian: Diestri so lipofilne komponente, ki zagotavljajo povečano prodiranje v kožo, povezano z nizko sistemsko biološko uporabnostjo.
English: Do not use this veterinary medicinal product after the expiry date, which is stated on the label.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na ovojnini.
English: Papules were observed uncommonly (less than 1% of treated dogs).
Slovenian: Občasno se pojavijo papule (pri manj kot 1 % zdravljenih psov).
English: Cardboard box containing 5, 10, 50, 100 or 200 pipettes.
Slovenian: Škatla iz lepenke, ki vsebuje 5, 10, 50, 100 ali 200 kapalk.
English: Incompatibilities: Do not mix with other veterinary medicinal products.
Slovenian: Inkompatibilnosti: Ne mešajte z nobenim drugim zdravilom za uporabo v veterinarski medicini.
English: Gentamicin resistant bacteria isolated from the field between 2008 and 2010 in canine otitis before treatment (determined according to CLSI guideline breakpoint ≥ 8 for all isolates except for Staphylococci ≥ 16 μg/ml) were low: 4.7%, 2.9% and 12.5% for Staphylococcus spp., Pseudomonas and Proteus spp.
Slovenian: Prisotnost bakterij, odpornih na gentamicin, ki so bile izolirane iz polja med 2008 in 2010 pri psih z otitisom pred zdravljenjem (določena po kritični kontrolni točki smernice CLS I≥ 8 za vse izolirane bakterije, razen za Staphylococci ≥ 16 μg/ml) je bila nizka: 4,7 %, 2,9 % in 12,5 % za Staphylococcus spp., Pseudomonas oz. Proteus spp.
English: The recommended dosage is 1 ml of the veterinary medicinal product per ear once a day for five consecutive days.
Slovenian: Priporočen odmerek je 1 ml zdravila za uporabo v veterinarski medicini na uho enkrat na dan v petih zaporednih dneh.
English: See section 4.5 of the SPC.
Slovenian: Glejte poglavje 4.5.
English: Its spectrum of activity includes Gram-positive and Gram-negative bacteria, such as the following pathogenic organisms isolated from the ears of dogs: Staphylococcus intermedius, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, etc.
Slovenian: Njegov spekter delovanja vključuje grampozitivne in gramnegativne bakterije, kot so naslednji patogeni organizmi, izolirani iz pasjih ušes: Staphylococcus intermedius, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli itd.
English: In case of eye irritation, seek medical advice.
Slovenian: V primeru razdraženosti oči se posvetujte z zdravnikom.
English: MARKETING AUTHORISATION NUMBER(S)
Slovenian: ŠTEVILKA DOVOLJENJA ZA PROMET)
English: Hydrocortisone aceponate - Miconazole - Gentamicin
Slovenian: Hidrokortizon aceponat - mikonazol - gentamicin
English: In laboratory animals, hydrocortisone aceponate is eliminated the same way as hydrocortisone (other name for endogenous cortisol) through urine and faeces.
Slovenian: Pri laboratorijskih živalih se hidrokortizon aceponat izloči na enak način kot hidrokortizon (drugo ime za endogeni kortizol), z urinom in fekalijami.
English: [Multi-dose container:] Shake the bottle thoroughly before first administration and prime the pump by pressing it.
Slovenian: [Večodmerni vsebnik:] Pred prvo uporabo dobro pretresite stekleničko in s pritiskom napolnite črpalko.
English: This dose is adequately delivered by one pump activation.
Slovenian: Odmerek je ustrezno izveden z enim pritiskom na črpalko.
English: In dogs treated at the therapeutic dose for ten consecutive days, serum cortisol levels decreased from five days onward and returned to normal values within ten days after the end of treatment.
Slovenian: Pri psih zdravljenih s terapevtskim odmerkom deset zaporednih dni, so se ravni kortizola v serumu zmanjšale od petega dne naprej in se vrnile na normalno vrednost v desetih dneh po koncu zdravljenja.
English: Co-resistance has been described, i.e. gentamicin resistance genes are found to be physically linked to other antimicrobial resistance genes that are transferred between pathogens due to transferable genetic elements such as plasmids, integrons and transposons.
Slovenian: Znana je soodpornost, tj. geni gentamicinske odpornosti so fizično povezani z drugimi geni antimikrobne odpornosti, ki se prenašajo med patogeni zaradi prenosljivih genskih elementov, kot so plazmidi, integroni in transposoni.
English: Hydrocortisone aceponate
Slovenian: Hidrokortizon aceponat
English: The airless pump allows the product to be administered whatever the position of the bottle is.
Slovenian: Brezzračna črpalka omogoča dajanje zdravila ne glede na položaj stekleničke.
English: In very rare cases, the use of the veterinary medicinal product has been associated with hearing impairment (partial hearing loss or deafness), usually temporary, and primarily in geriatric dogs.
Slovenian: V zelo redkih primerih je bilo zdravljenje z zdravilom za uporabo v veterinarski medicini povezano z okvaro sluha (delna izguba sluha ali gluhost), ki je bila običajno kratkotrajna in prisotna predvsem pri starejših psih.
English: Cross-resistance is mainly linked with efflux pumps which confer resistance to β-lactams, quinolones and tetracyclines depending on the specificity of the pump with its substrate.
Slovenian: Navzkrižna rezistenca je večinoma povezana z izlivnimi črpalkami, ki prenašajo odpornost na βlaktame, kinolone in tetracikline, odvisno od specifičnosti črpalke z njenim substratom.
English: In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Slovenian: V primeru nenamernega zaužitja se takoj posvetujte z zdravnikom in mu pokažite navodilo za uporabo ali nalepko.
English: If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate therapy instituted.
Slovenian: Če se pojavi preobčutljivost na katerokoli od sestavin, je treba prekiniti zdravljenje in začeti z ustrezno terapijo.
English: If this occurs, treatment should be stopped.
Slovenian: Če pride do takšnih reakcij, je treba prekiniti zdravljenje.
English: Gentamicin as sulphate
Slovenian: Gentamicin v obliki sulfata
English: Squeeze gently but firmly in the middle of the body of the pipette.
Slovenian: Nežno, a odločno stisnite osrednji del kapalke.
English: Bacterial and fungal otitis is often secondary in nature and appropriate diagnosis should be used to determine the primary factors involved.
Slovenian: Bakterijsko in glivično vnetje sluhovoda je pogosto sekundarne narave, zato je potrebna ustrezna diagnoza, ki bo določila vključene primarne dejavnike.
English: Tel.: 0033/4.92.08.73.00 Fax: 0033/4.92.08.73.48 E-mail: dar@virbac.fr
Slovenian: Tel.: 0033/4 92 08 73 00 Faks: 0033/4 92 08 7348 E-mail: dar@virbac.fr
English: 6000 Kolding
Slovenian: 6000 Kolding Tlf.
English: In case of parasitic otitis, an appropriate acaricidal treatment should be implemented.
Slovenian: V primeru parazitskega vnetja sluhovoda je treba začeti z ustreznim akaricidnim zdravljenjem.
English: United Kingdom VIRBAC LTD Suffolk IP30 9 UP Tel: 44 (0) 1359 243243
Slovenian: United Kingdom VIRBAC LTD UK-Suffolk IP30 9 UP Tel: 44 (0) 1359 243243
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE BOX OF 5, 10, 50, 100 or 200 PIPETTES
Slovenian: PODATKI NA ZUNANJI OVOJNINI ŠKATLA S 5, 10, 50, 100 ali 200 KAPALKAMI
English: Box containing 1 multi-dose container (the content of 10 ml is equivalent to 10 doses).
Slovenian: Škatla z eno večodmerno črpalko (vsebina 10 ml je enaka 10 odmerkom).
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Veterinary medicinal product subject to prescription.
Slovenian: B POGOJI IN OMEJITVE GLEDE OSKRBE IN UPORABE Na veterinarski recept.
English: At 3 and 5 times the recommended dose, no local or general adverse reactions were observed with the exception of some dogs showing erythema and papulae in the ear canal.
Slovenian: Pri tri- in petkrat večjem odmerku od priporočenega niso bile opažene lokalne ali splošne neželene reakcije z izjemo nekaterih psov, pri katerih so se pojavile rdečica in papule v ušesnem kanalu.
English: After application of the veterinary medicinal product into the ear canal, absorption of miconazole and gentamicin through the skin is negligible.
Slovenian: Po dajanju zdravila za uporabo v veterinarski medicini v ušesni kanal je absorpcija mikonazola in gentamicina skozi kožo zanemarljiva.
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals: In case of accidental skin contact, it is recommended to wash thoroughly with water.
Slovenian: Posebni previdnostni ukrepi, ki jih mora upoštevati oseba, ki daje zdravilo živalim: V primeru nenamernega stika kožo temeljito sperite z vodo.
English: Pregnancy and lactation:
Slovenian: Brejosti in laktacije:
English: C. STATEMENT OF THE MRLs Not applicable.
Slovenian: C. NAVEDBA NAJVIŠJIH DOVOLJENIH KOLIČIN ZAOSTANKOV ZDRAVILA (MRL) Ni smiselno.
English: In very rare cases, Type-I Hypersensitivity reactions (facial swelling, allergic pruritus) have been observed.
Slovenian: V zelo redkih primerih so bile opažene preobčutljivostne reakcije tipa I (zatekanje obraza, alergijski pruritus).
English: 1 dose x 100 1 dose x 200
Slovenian: 1 odmerek x 100 1 odmerek x 200
English: Compatibility with ear cleaners has not been demonstrated.
Slovenian: Ni podatkov o združljivosti tega zdravila s čistili za ušesa.
English: However, serum cortisol response levels post ACTH stimulation remained in the normal range during the extended treatment period, indicating a preserved adrenal function.
Slovenian: Vendar pa so odzivne ravni serumskega kortizola po stimulaciji z ACTH (adrenokortikotropin) med podaljšanim obdobjem zdravljenja ostali v normalnem razponu, kar kaže na ohranjeno funkcijo nadledvičnih žlez.
English: Miconazole nitrate is a synthetic imidazole derivative with a pronounced antifungal activity.
Slovenian: Mikonazol nitrat je sintetični derivat imidazola z znanim protiglivičnim delovanjem.
English: Multi-dose container composed of two extruded parts, one external white polypropylene rigid tube and one internal (ethylene-methacrylic acid)-zinc copolymer (Surlyn) flexible pouch containing a steel ball, closed with a 1 ml dosing airless pump equipped with a flexible atraumatic cannula and covered by a plastic cap.
Slovenian: Večodmerni vsebnik, sestavljen iz dveh ekstrudiranih delov, in sicer zunanje bele polipropilenske trdne stekleničke in notranje gibljive vrečke iz (etilen-metakrilno kislinskega) - cinkovega kopolimera (surlyn) in z jekleno kroglico, ki se zapira z enomililitrsko odmerno brezzračno črpalko z gibljivo atravmatsko kanilo in je pokrita s plastičnim pokrovčkom.
English: Use of the veterinary medicinal product should be based on identification of infecting organisms and susceptibility testing and take into account official and local antimicrobial policies.
Slovenian: Uporaba zdravila za uporabo v veterinarski medicini mora temeljiti na osnovi identifikacije in testiranju občutljivosti povzročiteljev ter upoštevati uradno in lokalno antimikrobno strategijo.
English: Gentamicin sulphate is an aminoglycoside bactericidal antibiotic which acts by inhibiting protein synthesis.
Slovenian: Gentamicin sulfat je aminoglikozidni bakterijski antibiotik, ki preprečuje sintezo proteinov.
English: The product as presented allows treating a dog suffering from bilateral otitis.
Slovenian: Predstavljeno zdravilo omogoča zdravljenje psov, ki imajo obojestransko vnetje ušesa.
English: To administer one dose (1 ml) of the product in the affected ear:
Slovenian: Za dajanje enega odmerka (1 ml) zdravila v prizadeto uho:
English: Miconazole as nitrate
Slovenian: Mikonazol v obliki nitrata
English: SPECIAL WARNING(S), IF NECESSARY Read the package leaflet before use.
Slovenian: POSEBNO OPOZORILO, ČE JE POTREBNO Pred uporabo preberite navodilo za uporabo.
English: Do not use concurrently with substances known to cause ototoxicity.
Slovenian: Ne uporabite hkrati z učinkovinami, ki povzročajo ototoksičnost.
English: CONDITIONS OR RESTRICTIONS REGARDING SUPPLY ANDUSE
Slovenian: POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE
English: The bacterial resistance phenotypes to gentamicin are mainly based on three mechanisms: enzymatic modification of aminoglycosides, failure of intracellular penetration of the active substance and alteration of the aminoglycoside target.
Slovenian: Fenotipi odpornosti bakterij na gentamicin večinoma temeljijo na treh mehanizmih: encimski prilagoditvi aminoglukozidov, neuspešnem znotrajceličnem prodiranju zdravilne sestavine in spremembi aminoglikozidne tarče.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/08/085/001
Slovenian: ŠTEVILKA DOVOLJENJA ZA PROMET EU/2/08/085/001
English: Miconazole selectively inhibits the synthesis of ergosterol, which is an essential component of the membrane of yeasts and fungi including Malassezia pachydermatis.
Slovenian: Mikonazol selektivno preprečuje sintezo ergosterola, ki je bistvena sestavina membrane kvasovk in glivic, vključno z vrsto Malassezia pachydermatis.