FrancophonIA/ELRC3.0 huggingface dataset:
English: Vipdomet must be discontinued prior to or at the time of the imaging procedure and not restarted until at least 48 hours after, provided that renal function has been re-evaluated and found to be stable, see sections 4.2 and 4.4.
Danish: Behandling med Vipdomet skal afbrydes forud for eller på tidspunktet for en billeddiagnostisk procedure og først genoptages efter mindst 48 timer, forudsat at nyrefunktionen er blevet vurderet og fundet stabil, se pkt.
English: More patients receiving 25 mg alogliptin and metformin (48.5%) achieved target HbA1c levels of ≤7.0% compared to those receiving glipizide and metformin (42.8%) (p=0.004).
Danish: Flere patienter, der fik 25 mg alogliptin og metformin (48,5 %) nåede behandlingsmålet for HbA1c-niveau på ≤ 7,0 % sammenlignet med dem, der fik glipizid og metformin (42,8 %) (p=0,004).
English: Primary Composite Endpoint [First Event of CV Death, Nonfatal MI and Nonfatal Stroke]
Danish: Primært sammensat endepunkt [første hændelse af KV-død, ikkedødeligt MI og ikke-dødelig apopleksi] Kardiovaskulær død* Ikke-dødeligt myokardieinfarkt Ikke-dødelig apopleksi
English: INFORMATION IN BRAILLE Vipdomet 12.5 mg/1000 mg
Danish: INFORMATION I BRAILLESKRIFT Vipdomet 12,5 mg/1.000 mg
English: For patients inadequately controlled on dual combination therapy with insulin and the maximal tolerated dose of metformin, the dose of Vipdomet should provide alogliptin dosed at 12.5 mg twice daily (25 mg total daily dose) and a dose of metformin similar to the dose already being taken.
Danish: Patienter, der ikke opnår tilstrækkelig kontrol ved tostofbehandling sammen med insulin og den maksimalt tolererede dosis metformin, får via en dosis Vipdomet tilført 12,5 mg alogliptin to gange dagligt (25 mg i alt pr. dag) og en dosis metformin svarende til den, som de allerede får.
English: Isolated cases of hepatitis or liver function test abnormalities resolving on discontinuation of metformin have been reported.
Danish: Der er indberettet enkelte tilfælde af hepatitis og uregelmæssige værdier er set i leverfunktionstest, som er forsvundet igen ved ophør med metformin.
English: Add-on combination therapy studies Alogliptin 25 mg once daily with metformin vs a sulphonylurea + metformin
Danish: Tillægsbehandlingsstudier Alogliptin 25 mg én gang dagligt sammen med metformin versus et sulfonylurinstof + metformin
English: The addition of 25 mg alogliptin once daily to 30 mg pioglitazone in combination with metformin hydrochloride therapy (mean dose = 1,867.9 mg) resulted in improvements from baseline in HbA1c at Week 52 that were both non-inferior and statistically superior to those produced by 45 mg pioglitazone in combination with metformin hydrochloride therapy (mean dose = 1,847.6 mg, Table 3).
Danish: Administration af 25 mg alogliptin én gang dagligt som tillæg til 30 mg pioglitazon plus metforminbehandling (gennemsnitlig dosis = 1.867,9 mg) medførte forbedringer i HbA1c fra baseline til uge 52, der var både non-inferiøre og statistisk større end dem, der blev opnået ved administration af 45 mg pioglitazon og metforminbehandling gav (gennemsnitlig dosis = 1.847,6 mg, tabel 3).
English: The results of bioequivalence studies in healthy subjects demonstrated that Vipdomet film-coated tablets are bioequivalent to the corresponding doses of alogliptin and metformin co-administered as separate tablets.
Danish: Bioækvivalensstudier med raske forsøgspersoner viser, at Vipdomet, filmovertrukne-tabletter er bioækvivalente med tilsvarende doser af alogliptin og metformin givet samtidigt som separate tabletter.
English: - Severe and persistent pain in the abdomen (stomach area) which might reach through to your back as well as nausea and vomiting, as it could be a sign of an inflamed pancreas (pancreatitis).
Danish: • Stærke og vedvarende smerter i maven, som kan stråle ud i ryggen, samt kvalme og opkastning.
English: Hepatic impairment Vipdomet should not be used in patients with hepatic impairment (see section 4.2).
Danish: Nedsat leverfunktion Vipdomet må ikke anvendes til patienter med nedsat leverfunktion (se pkt.
English: The symptoms may include: a rash, hives, swallowing or breathing problems, swelling of your lips, face, throat or tongue and feeling faint.
Danish: Tegnene kan være udslæt, nældefeber, synke- eller åndedrætsbesvær, hævelse af læber, ansigt, svælg eller tunge og besvimelsesfornemmelse.
English: How to take Vipdomet
Danish: Sådan skal du tage Vipdomet
English: Do not take Vipdomet: - if you are allergic to alogliptin, metformin or any of the other ingredients of this medicine (listed in section 6) - if you have had a serious allergic reaction to any other similar medicines that you take to control your blood sugar.
Danish: • hvis du er allergisk over for alogliptin, metformin eller et af de øvrige indholdsstoffer i dette lægemiddel (angivet i punkt 6).
English: Symptoms may include: trembling, sweating, anxiety, blurred vision, tingling lips, paleness,
Danish: Tegnene kan være: rysten, svedtendens, angst, sløret syn, prikkende fornemmelse i læber, bleghed, humørsvingninger eller forvirring.
English: Mean change from baseline in fasting plasma glucose at Week 52 for 25 mg alogliptin and metformin was significantly greater than that for glipizide and metformin (p<0.001).
Danish: Endvidere var den gennemsnitlige ændring i fasteplasmaglucose fra baseline til uge 52 for 25 mg alogliptin plus metformin signifikant større end for glipizid plus metformin (p<0,001).
English: For the different dose regimens Vipdomet is available in strengths of 12.5 mg/850 mg and 12.5 mg/1,000 mg film-coated tablets.
Danish: Vipdomet fås som filmovertrukne tabletter i styrkerne 12,5 mg/850 mg og 12,5 mg/1.000 mg.
English: Significantly more patients receiving 25 mg alogliptin plus 30 mg pioglitazone and metformin (33.2%) achieved target HbA1c levels of ≤7.0% compared to those receiving 45 mg pioglitazone and metformin (21.3%) at Week 52 (p<0.001).
Danish: Signifikant flere af de patienter, der fik 25 mg alogliptin og 30 mg pioglitazon og metformin (33,2 %), nåede behandlingsmålet i uge 52 (p<0,001) for HbA1c på ≤ 7,0 % i forhold til de patienter, der fik 45 mg pioglitazon og metformin (21,3 %).
English: - if you have a severe infection or are seriously dehydrated (have lost a lot of water from your body) - if you recently had a heart attack or have severe circulatory problems including shock - if you have severe breathing difficulties - if you have liver disease - if you drink alcohol excessively (either every day or in large quantities only from time to time)
Danish: • hvis du for nyligt har haft et hjerteanfald eller har svære kredsløbsproblemer, herunder shock.
English: The addition of 25 mg alogliptin once daily to metformin hydrochloride therapy (mean dose = 1,847 mg) resulted in statistically significant improvements from baseline in HbA1c and fasting plasma glucose at Week 26 when compared to the addition of placebo (Table 2).
Danish: Tillæg af 25 mg alogliptin én gang dagligt til metforminbehandling (gennemsnitlig dosis = 1.847 mg) resulterede i statistisk signifikante forbedringer af HbA1c og fasteplasmaglucose fra baseline til uge 26 sammenlignet med tillæg af placebo (tabel 2).
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 12.5 mg alogliptin (as benzoate) and 1,000 mg metformin hydrochloride.
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver tablet indeholder 12,5 mg alogliptin (som benzoat) og 1.000 mg metforminhydrochlorid.
English: becoming breathless - Liver problems (hepatitis or liver function test abnormalities) - Erythema (redness of skin).
Danish: • problemer med leveren (hepatitis eller unormale leverfunktionstest).
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 12.5 mg alogliptin (as benzoate) and 850 mg metformin hydrochloride.
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver tablet indeholder 12,5 mg alogliptin (som benzoat) og 850 mg metforminhydrochlorid.
English: Studies in pregnant rats with alogliptin plus metformin as combination treatment have shown reproductive toxicity (see section 5.3) at approximately 5-20 times (for metformin and alogliptin respectively) the human exposure at the recommended dose.
Danish: 5.3) ved doser, som er ca. 5-20 gange højere (for henholdsvis metformin og alogliptin) end den humane eksponering ved den anbefalede dosis.
English: NAME OF THE MEDICINAL PRODUCT Vipdomet 12.5 mg/850 mg film-coated tablets Vipdomet 12.5 mg/1,000 mg film-coated tablets
Danish: LÆGEMIDLETS NAVN Vipdomet 12,5 mg/850 mg filmovertrukne tabletter Vipdomet 12,5 mg/1.000 mg filmovertrukne tabletter
English: However, dosing of alogliptin should be conservative in patients with advanced age due to the potential for decreased renal function in this population
Danish: Dosisjustering er ikke nødvendig på grund af alder. Der bør dog udvises forsigtighed ved doseringen af alogliptin til ældre patienter, da de har forhøjet risiko for nedsat nyrefunktion.
English: In addition, mean change from baseline in FPG at Week 52 for 25 mg alogliptin plus 30 mg pioglitazone and metformin was significantly greater than that for 45 mg pioglitazone and metformin (p<0.001).
Danish: Den gennemsnitlige ændring i fasteplasmaglucose fra baseline til uge 52 ved administration af 25 mg alogliptin plus 30 mg pioglitazon plus metformin var desuden signifikant større end den gennemsnitlige ændring, der blev registreret ved administration af 45 mg pioglitazon plus metformin (p<0,001).
English: In case of suspected symptoms, the patient should stop taking Vipdomet and seek immediate medical attention.
Danish: Patienterne skal informeres om at stoppe med at tage Vipdomet og øjeblikkeligt søge lægehjælp ved symptomer, der kan give mistanke om laktatacidose.
English: Alogliptin as add-on therapy to metformin with a thiazolidinedione The addition of 25 mg alogliptin once daily to pioglitazone therapy (mean dose = 35.0 mg, with or without metformin or a sulphonylurea) resulted in statistically significant improvements from baseline in HbA1c and fasting plasma glucose at Week 26 when compared to the addition of placebo (Table 2).
Danish: Alogliptin som tillæg til metformin sammen med et thiazolidindion Tillæg af 25 mg alogliptin én gang dagligt til pioglitazonbehandling (gennemsnitlig dosis = 35,0 mg, med eller uden metformin eller sulfonylurinstof) resulterede i statistisk signifikante forbedringer af HbA1c og fasteplasmaglucose i forhold til baseline i uge 26 sammenlignet med tillæg af placebo (tabel 2).
English: Alogliptin as add-on therapy to metformin with insulin The addition of 25 mg alogliptin once daily to insulin therapy (mean dose = 56.5 IU, with or without metformin) resulted in statistically significant improvements from baseline in HbA1c and FPG at Week 26 when compared to the addition of placebo (Table 2).
Danish: Alogliptin som tillæg til metformin sammen med insulin Tillæg af 25 mg alogliptin én gang dagligt til insulinbehandling (gennemsnitlig dosis = 56,5 IE, med eller uden metformin) resulterede i statistisk signifikante forbedringer af HbA1c og fasteplasmaglucose fra baseline til uge 26 sammenlignet med tillæg af placebo (tabel 2).
English: What Vipdomet is and what it is used for What you need to know before you take Vipdomet How to take Vipdomet
Danish: Det skal du vide, før du begynder at tage Vipdomet Sådan skal du tage Vipdomet Bivirkninger
English: More patients receiving 25 mg alogliptin (7.8%) achieved target HbA1c levels of ≤7.0% compared to those receiving placebo (0.8%) at Week 26.
Danish: Flere af de patienter, der fik 25 mg alogliptin (7,8 %), nåede behandlingsmålet i uge 26 for HbA1c på ≤ 7,0 %, sammenlignet med de placebobehandlede patienter (0,8 %).
English: Significantly more patients receiving 25 mg alogliptin (44.4%) achieved target HbA1c levels of ≤7.0% compared to those receiving placebo (18.3%) at Week 26 (p<0.001).
Danish: Signifikant flere patienter, der fik 25 mg alogliptin (44,4 %), nåede i uge 26 behandlingsmålet for HbA1c på ≤ 7,0 % sammenlignet med de placebobehandlede patienter (18,3 %) (p<0,001).
English: Each 12.5 mg/850 mg film-coated tablet contains alogliptin benzoate equivalent to 12.5 mg alogliptin and 850 mg metformin hydrochloride.
Danish: - Hver 12,5 mg/850 mg filmovertrukken tablet indeholder alogliptinbenzoat svarende til 12,5 mg alogliptin og 850 mg metforminhydrochlorid.
English: Each 12.5 mg/1,000 mg film-coated tablet contains alogliptin benzoate equivalent to 12.5 mg alogliptin and 1,000 mg metformin hydrochloride.
Danish: - Hver 12,5 mg/1.000 mg filmovertrukken tablet indeholder alogliptinbenzoat svarende til 12,5 mg alogliptin og 1.000 mg metforminhydrochlorid.
English: mood change or feeling confused.
Danish: svaghedsfornemmelse og stakåndethed.
English: - Vipdomet 12.5 mg/1,000 mg film-coated tablets (tablets) are pale yellow, oblong (approximately 22.3 mm long by 10.7 mm wide), biconvex, film-coated tablets with “12.5/1000” debossed on one side and “322M” debossed on the other side.
Danish: - Vipdomet 12,5 mg/1.000 mg filmovertrukne tabletter (tabletter) er svagt gule, aflange (ca. 22,3 x 10,7 mm), bikonvekse filmovertrukne tabletter, der er præget med "12.5/1000" på den ene side og "322M" på den anden side.
English: Significantly more patients receiving 25 mg alogliptin (49.2%) achieved target HbA1c levels of ≤7.0% compared to those receiving placebo (34.0%) at Week 26 (p=0.004).
Danish: Signifikant flere af de patienter, der fik 25 mg alogliptin (49,2 %), nåede behandlingsmålet i uge 26 (p=0,004) for HbA1c på ≤ 7,0 %, i forhold til de placebobehandlede patienter (34,0 %).
English: What Vipdomet looks like and contents of the pack - Vipdomet 12.5 mg/850 mg film-coated tablets (tablets) are light yellow, oblong (approximately 21.0 mm long by 10.1 mm wide), biconvex, film-coated tablets with “12.5/850” debossed on one side and “322M” debossed on the other side.
Danish: Udseende og pakningsstørrelser - Vipdomet 12,5 mg/850 mg filmovertrukne tabletter (tabletter) er lysegule, aflange (ca. 21,0 x 10,1 mm), bikonvekse filmovertrukne tabletter, der er præget med "12.5/850" på den ene side og "322M" på den anden side.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/13/843/026 196 (2x98) film-coated tablets (multipack)
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/13/843/026 196 (2x98) filmovertrukne tabletter (multipakning)
English: Very rare: - Decreased vitamin B12 levels or anaemia; symptoms include tiredness, lethargy, feeling faint,
Danish: • nedsat B12-vitaminniveau eller anæmi.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/13/843/025 196 (2x98) film-coated tablets (multipack)
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/13/843/025 196 (2x98) filmovertrukne tabletter (multipakning)
English: loss of appetite, dark urine or yellowing of your skin or the whites of your eyes.
Danish: • leverproblemer, der viser sig som kvalme, opkastning, mavesmerter, usædvanlig eller uforklarlig træthed, manglende appetit, mørkfarvet urin eller gulfarvning af huden eller det hvide i øjnene.
English: Mean change from baseline in HbA1c (%)† (SE)
Danish: Gennem-snitlig ændring i HbA1c fra baseline (%)† (SE)
English: MARKETING AUTHORISATION NUMBER(S) EU/1/13/843/025 2x98 film-coated tablets
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/13/843/025 2x98 filmovertrukne tabletter
English: Hepatobiliary disorders hepatitis very rare
Danish: Metabolisme og ernæring laktatacidose meget sjælden
English: MARKETING AUTHORISATION NUMBER(S) EU/1/13/843/026 2x98 film-coated tablets
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/13/843/026 2x98 filmovertrukne tabletter
English: Vipdomet 12.5 mg/850 mg film-coated tablets Vipdomet 12.5 mg/1000 mg film-coated tablets alogliptin/metformin hydrochloride
Danish: Indlægsseddel: Information til patienten Vipdomet 12,5 mg/850 mg filmovertrukne tabletter Vipdomet 12,5 mg/1.000 mg filmovertrukne tabletter alogliptin/metforminhydrochlorid
English: NAME OF THE MEDICINAL PRODUCT Vipdomet 12.5 mg/1,000 mg tablets alogliptin/metformin hydrochloride
Danish: LÆGEMIDLETS NAVN Vipdomet 12,5 mg/1.000 mg tabletter alogliptin/metforminhydrochlorid
English: NAME OF THE MEDICINAL PRODUCT Vipdomet 12.5 mg/850 mg tablets alogliptin/metformin hydrochloride
Danish: LÆGEMIDLETS NAVN Vipdomet 12,5 mg/850 mg tabletter alogliptin/metforminhydrochlorid
English: If you take more Vipdomet than you should
Danish: Hvis du har taget for meget Vipdomet
English: Pharmacotherapeutic group: Drugs used in diabetes; combinations of oral blood glucose lowering drugs.
Danish: Farmakoterapeutisk klassifikation: antidiabetika; komb.
English: NAME OF THE MEDICINAL PRODUCT Vipdomet 12.5 mg/1,000 mg film-coated tablets alogliptin/metformin hydrochloride
Danish: LÆGEMIDLETS NAVN Vipdomet 12,5 mg/1.000 mg filmovertrukne tabletter alogliptin/metforminhydrochlorid
English: NAME OF THE MEDICINAL PRODUCT Vipdomet 12.5 mg/850 mg film-coated tablets alogliptin/metformin hydrochloride
Danish: LÆGEMIDLETS NAVN Vipdomet 12,5 mg/850 mg filmovertrukne tabletter alogliptin/metforminhydrochlorid
English: Treatment-corrected change from baseline in HbA1c (%)†
Danish: Behandlingskorrigeret ændring i HbA1c (%)† (en-sidet
English: - Cold symptoms such as sore throat, stuffy or blocked nose, feeling tired, fever, chills, dry cough - Rash - Itchy skin with or without hives - Headache - Indigestion, heartburn - Vomiting and/or diarrhoea - Metallic taste.
Danish: • forkølelsessymptomer som ondt i halsen, tilstoppet næse, træthed, feber, kulderystelser og tør hoste
English: Pale yellow, oblong (approximately 22.3 mm long by 10.7 mm wide), biconvex, film-coated tablets with “12.5/1000” debossed on one side and “322M” debossed on the other side.
Danish: Vipdomet 12,5 mg/1.000 mg filmovertrukne tabletter Svagt gule, aflange (ca. 22,3 mm lange og 10,7 mm brede), bikonvekse, filmovertrukne tabletter med "12.5/1000" præget på den ene side og "322M" på den anden side.
English: - Hypersensitivity to the active substances or to any of the excipients listed in section 6.1 or history of a serious hypersensitivity reaction, including anaphylactic reaction, anaphylactic shock, and angioedema, to any dipeptidyl-peptidase-4 (DPP-4) inhibitor (see sections 4.4 and 4.8) - Any type of acute metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis) - Diabetic pre-coma - Severe renal failure (GFR <30 mL/min) - Acute conditions with the potential to alter renal function such as: - dehydration - severe infection - shock - Acute or chronic disease which may cause tissue hypoxia (see section 4.4) such as: - cardiac or respiratory failure - recent myocardial infarction - shock - Hepatic impairment (see section 4.4) - Acute alcohol intoxication, alcoholism (see sections 4.4 and 4.5)
Danish: 6.1 eller en tidligere alvorlig overfølsomhedsreaktion, herunder anafylaktisk reaktion, anafylaktisk shock og angioødem, eller over for en dipeptidyl-peptidase-4 (DPP-4)-hæmmer (se pkt.
English: Hepatic impairment
Danish: - mavesmerter
English: Light yellow, oblong (approximately 21.0 mm long by 10.1 mm wide), biconvex, film-coated tablets with “12.5/850” debossed on one side and “322M” debossed on the other side.
Danish: Vipdomet 12,5 mg/850 mg filmovertrukne tabletter Lysegule, aflange (ca. 21,0 mm lange og 10,1 mm brede), bikonvekse, filmovertrukne tabletter med "12.5/850" præget på den ene side og "322M" på den anden side.
English: (1-sided CI)
Danish: (%)† (SE)
English: Lactic acidosis
Danish: • mavesmerter
English: This summary was last updated in October 2008.
Danish: Dette sammendrag blev sidst ajourført i 10-2008.
English: The withdrawal period of the product is zero days.
Danish: Produktets tilbageholdelsestid er nul dage.
English: In some cases fever may occur for one day, and up to three days in exceptional circumstances.
Danish: I nogle tilfælde kan der opstå feber i én dag, og op til tre dage i sjældne tilfælde.
English: All studies were performed with Equilis Prequenza Te (comment: double; mentioned in next paragraph).
Danish: Alle undersøgelserne blev foretaget med Equilis Prequenza Te (kommentar: dobbelt; nævnt i næste afsnit).
English: Afterwards, a maximum interval of two years is recommended.
Danish: Herefter anbefales et maksimuminterval på to år.
English: The European Commission granted a marketing authorisation valid throughout the European Union, for Equilis Te to Intervet International BV on 8 July 2005.
Danish: Europa-Kommissionen udstedte en markedsføringstilladelse med gyldighed i hele Den Europæiske Union for Equilis Te til Intervet International BV den 8. juli 2005.
English: Other information about Equilis Te:
Danish: Andre oplysninger om Equilis Te:
English: The vaccine is given as an injection into a muscle.
Danish: Vaccinen gives som injektion i en muskel.
English: The Committee recommended that Equilis Te should be given a marketing authorisation.
Danish: Udvalget anbefalede udstedelse af markedsføringstilladelse for Equilis Te.
English: The toxoid is a toxin processed in order to remove its toxic effect, but retain its antigenic properties.
Danish: Dette toksoid er et toksin, der er bearbejdet for at fjerne dets toksiske virkning, men bevare dets antigene egenskaber.
English: Swelling (max. diameter 5 cm) may occur at the injection site, either as diffuse hard or soft swelling.
Danish: diameter på 5 cm) kan forekomme ved injektionsstedet, enten som diffus hård eller blød hævelse.
English: When the product is given to horses, it helps the animals' immune system to react quicker when the animal is naturally exposed to the Clostridium tetani bacterium.
Danish: Når heste vaccineres med produktet, hjælper det dyrets immunsystem til at reagere hurtigere, hvis dyret på naturlig vis skulle blive udsat for bakterien Clostridium tetani.
English: The vaccine also contains an ‘adjuvant' to stimulate a better immune response.
Danish: Vaccinen indeholder desuden et "adjuvans", der forstærker immunresponset.
English: Pain at the injection site can occur occasionally.
Danish: Der kan af og til opstå smerter ved injektionsstedet.
English: The effectiveness of Equilis Te has been studied in several trials under laboratory and field conditions.
Danish: Virkningen af Equilis Te er blevet undersøgt i flere undersøgelser under laboratorie- og feltbetingelser.
English: It is available as a suspension for injection.
Danish: Vaccinen findes som suspension til injektion.
English: No negative influence on gestation, foaling and offspring of mares was observed after vaccination at different times during pregnancy.
Danish: Der blev ikke observeret nogen negativ indvirkning på svangerskabet, folingen eller afkommet blandt disse heste, efter at de var blevet vaccineret på forskellige tidspunkter under drægtigheden.
English: It contains the toxoid (chemically inactivated toxin) from the tetanus bacterium.
Danish: Den indeholder toksoid (kemisk inaktiveret toksin) fra tetanusbakterien.
English: Tetanus is an acute, often fatal disease caused by a neurotoxin produced by the bacterium Clostridium tetani.
Danish: Stivkrampe er en akut, ofte dødelig sygdom, som skyldes et neurotoksin, der produceres af bakterien Clostridium tetani.
English: To retain protection against tetanus, horses need to be revaccinated.
Danish: For at beskyttelsen mod stivkrampe kan vare ved, skal hestene vaccineres igen.
English: The safety of Equilis Te was studied in several studies under laboratory and field conditions in a large number of horses, from 2 months of age.
Danish: Sikkerheden af Equilis Te blev undersøgt i adskillige undersøgelser under laboratorie- og feltbetingelser i et stort antal heste, fra tomånedersalderen og opefter.
English: The first revaccination should be no later than 17 months after primary vaccination.
Danish: Den første revaccination bør finde sted senest 17 måneder efter basisvaccinationen.
English: The duration of protection against tetanus was 17 months after primary vaccination and 24 months after the first revaccination.
Danish: Varigheden af beskyttelse mod stivkrampe var 17 måneder efter basisvaccination og 24 måneder efter den første revaccination.
English: What is the risk associated with Equilis Te?
Danish: Hvilken risiko er der forbundet med Equilis Te?
English: Horses developed protection two weeks after primary vaccination.
Danish: Hestene dannede beskyttelse to uger efter basisvaccination.