FrancophonIA/ELRC3.0 huggingface dataset:
English: Coadministration of voriconazole and low dose ritonavir (100 mg twice daily) should be avoided unless an assessment of the benefit/risk to the patient justifies the use of voriconazole (see sections 4.3 and 4.5).
Icelandic: Aðeins skal nota vórikónazól samtímis rítónavíri í litlum skömmtum (100 mg tvisvar sinnum á sólarhring) ef mat á ávinningi/áhættu fyrir sjúklinginn réttlætir notkun vórikónazóls (sjá kafla 4.3 og kafla 4.5).
English: • Health Care Professional (HCP) Question and Answer Brochure for Phototoxicity, SCC and Hepatic toxicity;
Icelandic: Bæklingur fyrir heilbrigðisstarfsfólk með spurningum og svörum um ljóseiturhrif, flöguþekjukrabbamein og eiturverkanir á lifur;
English: 400 mg every 12 hours 200 mg every 12 hours
Icelandic: 400 mg á 12 klst. fresti
English: CARTON (Blister pack for 200 mg film-coated tablets - Pack of 2, 10, 14, 20, 28, 30, 50, 56, 100)
Icelandic: - Pakkning með 2, 10, 14, 20, 28, 30, 50, 56, 100 töflum)
English: If you stop taking Voriconazole Accord
Icelandic: Ef hætt er að nota Voriconazole Accord
English: Aspergillus infections - efficacy in aspergillosis patients with poor prognosis Voriconazole has in vitro fungicidal activity against Aspergillus spp.
Icelandic: Vórikónazól hefur in vitro sýnt sveppadeyðandi áhrif á Aspergillus spp.
English: [potent CYP450 inducer; CYP3A4 inhibitor and substrate]
Icelandic: [öflugur CYP450 virkir, CYP3A4 hemill og hvarfefni]
English: Therapy must be initiated with the specified loading dose regimen of either intravenous or oral voriconazole to achieve plasma concentrations on Day 1 that are close to steady state.
Icelandic: Hefja á meðferð með gjöf ákveðinna hleðsluskammta, annaðhvort með gjöf vórikónazóls í bláæð eða til inntöku, til að ná á fyrsta degi sem næst stöðugri plasmaþéttni.
English: When voriconazole treatment is stopped, the initial dose of efavirenz should be restored (see section 4.2 and 4.4).
Icelandic: Þegar gjöf vórikónazóls er hætt skal gefa upphaflegan skammt af efavírenzi (sjá kafla 4.2 og 4.4).
English: As the half-life of alfentanil is prolonged in a 4-fold manner when alfentanil is coadministered with voriconazole, and in an independent published study concomitant use of voriconazole with fentanyl resulted in an increase in the mean AUC0-∞ of fentanyl, frequent monitoring for opiate-associated adverse reactions (including a longer respiratory monitoring period) may be necessary.
Icelandic: Þörf getur verið á reglulegu eftirliti með aukaverkunum tengdum ópíóíðum (þ.m.t. lengra eftirlit með öndun) vegna þess að helmingunartími alfentaníls lengist 4-falt þegar það er gefið samtímis vórikónazóli, og hefur verið greint frá hækkuðum meðalgildum AUC 0-∞ fyrir fentanýl við samtímis notkun vorikónazóls og fentanýls í sjálfstæðri birtri rannsókn.
English: If Voriconazole Accord is continued, however, dermatologic evaluation should be performed on a systematic and regular basis, to allow early detection and management of premalignant lesions.
Icelandic: Ef meðferð með Voriconazole Accord er haldið skal leggja mat á ástand húðar reglulega og með kerfisbundnum hætti í því skyni að greina og meðhöndla skemmdir á forstigi tímanlega.
English: When voriconazole is coadministered with efavirenz the dose of voriconazole should be increased to 400 mg every 12 hours and the dose of efavirenz should be decreased to 300 mg every 24 hours (see sections 4.2, 4.3 and 4.5).
Icelandic: Þegar vórikónazól og efavírenz eru gefin samtímis skal auka skammt vórikónazóls í 400 mg á 12 klst. fresti og minnka skammtinn af efavírenzi í 300 mg á 24 klst. fresti (sjá kafla 4.2, 4.3 og 4.5).
English: The safety profile of voriconazole in adults is based on an integrated safety database of more than 2,000 subjects (including 1,603 adult patients in therapeutic trials) and an additional 270 adults in prophylaxis trials.
Icelandic: Öryggi vórikónazóls hjá fullorðnum er byggt á samþættum upplýsingagrunni um öryggi lyfsins hjá yfir 2.000 einstaklingum (þ.m.t.
English: [CYP2C9 substrate and potentCYP450 inducer]
Icelandic: [CYP2C9 hvarfefni og kröftugur CYP450 virkir]
English: Severe cutaneous adverse reactions (SCARs) including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS), which can be life-threatening or fatal, have been reported with the use of voriconazole.
Icelandic: Tilkynnt hefur verið um alvarlegar aukaverkanir í húð (SCAR) þ.m.t. Stevens-Johnson heilkenni (SJS), eitrunardreplos húðþekjuog (TEN) útbrot af völdum lyfja með fjölgunrauðkyrninga ogaltækum einkennum (DRESS), sem getaverið lífshættulegareða banvænar, viðnotkun voríkónazóls.
English: [CYP3A4 inhibitor]
Icelandic: [CYP3A4 hemill]
English: Although not studied, voriconazole is likely to increase the plasma concentrations of vinca alkaloids and lead to neurotoxicity.
Icelandic: Þó engar rannsóknir hafi verið gerðar er líklegt að vórikónazól hækki plasmaþéttni vinka alkalóíða og valdi eituráhrifum á taugar.
English: Efavirenz 400 mg QD, coadministered with voriconazole 200 mg BID*
Icelandic: Efavírenz 400 mg QD gefið samtímis vórikónazóli 200 mg BID*
English: Frequent monitoring for adverse reactions and toxicity related to methadone, including QTc prolongation, is recommended.
Icelandic: Títt eftirlit með aukaverkunum og eiturverkunum tengdum metadóni, þ.m.t. lengingu
English: A placebo-controlled, randomized, single-dose, crossover study to evaluate the effect on the QTc interval of healthy volunteers was conducted with three oral doses of voriconazole and ketoconazole.
Icelandic: Til að meta áhrif á QTc-bil hjá heilbrigðum sjálfboðaliðum var gerð víxluð slembivalsrannsókn á stökum skammti með samanburði við lyfleysu og voru notaðir þrír skammtar af vórikónazóli og ketakónazóli til inntöku.
English: Visual impairments
Icelandic: - Frávik á hjartarafriti
English: optic disc swelling - Decreased sensitivity to touch - Abnormal sense of taste - Hearing difficulties, ringing in the ears, vertigo - Inflammation of certain internal organs- pancreas and duodenum, swelling and inflammation of the tongue - Enlarged liver, liver failure, gallbladder disease, gallstones - Joint inflammation, inflammation of the veins under the skin (which may be associated with the formation of a blood clot) - Inflammation of the kidney, proteins in the urine, damage to the kidney - Very fast heart rate or skipped heartbeats, sometimes with erratic electrical impulses - Abnormal electrocardiogram (ECG) - Blood cholesterol increased, blood urea increased - Allergic skin reactions (sometimes severe), including life-threatening skin condition that causes painful blisters and sores of the skin and mucous membranes, especially in the mouth,
Icelandic: - Bragðskynstruflanir - Heyrnarskerðing, eyrnasuð, svimi - Bólga í tilteknum innri líffærum - brisi og skeifugörn, þrútin og bólgin tunga - Stækkuð lifur, lifrarbilun, sjúkdómur í gallblöðru, gallsteinar - Liðbólga, bólga í æðum undir húðinni (sem getur tengst myndun blóðtappa) - Bólga í nýrum, prótein í þvagi, nýrnaskemmdir - Mjög hraður hjartsláttur eða óreglulegur hjartsláttur, stundum með óreglulegum rafboðum
English: Non-Steroidal AntiInflammatory Drugs (NSAIDs)
Icelandic: Bólgueyðandi gigtarlyf (NSAID)
English: Completed at least 100 days of study drug prophylaxis Survived to day 180
Icelandic: Ífarandi gegnumbrots sveppasýkingar - dagur 180 Árangur á degi 180*
English: Eye disorders visual impairment6 retinal haemorrhage optic nerve disorder7, papilloedema8, oculogyric crisis, diplopia, scleritis, blepharitis optic atrophy, corneal opacity
Icelandic: , doppubjúgur8, augnvöðvaspennu truflun (oculogyric crisis), tvísýni, hvítubólga, hvarmabólga sjóntaugarvisnun, ógegnsæi glæru
English: NAME OF THE MEDICINAL PRODUCT Voriconazole Accord 200 mg film-coated tablets voriconazole NAME OF THE MARKETING AUTHORISATION HOLDER Accord EXPIRY DATE
Icelandic: HEITI LYFS Voriconazole Accord 200 mg filmuhúðaðar töflur vórikónazól NAFN MARKAÐSLEYFISHAFA Accord FYRNINGARDAGSETNING
English: Infections and infestations sinusitis pseudomembranou s colitis
Icelandic: Sýkingar af völdum sýkla og sníkjudýra skútabólga sýndarhimnuristil bólga (pseudomembran ous colitis)
English: 2 to <12.
Icelandic:  3,6-falt
English: During oral administration of 200 mg or 300 mg twice daily for 14 days in patients at risk of aspergillosis (mainly patients with malignant neoplasms of lymphatic or haematopoietic tissue), the observed pharmacokinetic characteristics of rapid and consistent absorption, accumulation and nonlinear pharmacokinetics were in agreement with those observed in healthy subjects.
Icelandic: Sjúklingar sem eru í aukinni hættu að fá ýrumyglusýkingar (aðallega sjúklingar með illkynja æxli í eitlum eða blóðmyndandi vef) fengu 200 mg eða 300 mg í inntöku tvisvar sinnum á sólarhring í 14 sólarhringa og reyndust lyfjahvörf þeirra sambærileg við lyfjahvörf heilbrigðra einstaklinga hvað varðar hraða og áreiðanleika frásogs, uppsöfnun og hversu ólínuleg þau eru.
English: Voriconazole Accord 50 mg film-coated tablets Voriconazole Accord 200 mg film-coated tablets voriconazole
Icelandic: Voriconazole Accord 50 mg filmuhúðaðar töflur Voriconazole Accord 200 mg filmuhúðaðar töflur vórikónazól
English: • St John's Wort (herbal supplement)
Icelandic:  Jónsmessurunni (jóhannesarjurt, St John´s Wort) (náttúrulyf)
English: Other oral coumarins (e.g., phenprocoumon, acenocoumarol)
Icelandic: Önnur kúmarín til inntöku (t.d. fenprókúmon, asenókúmaról)
English: Advises HCPs on the risks of phototoxicity, skin SCC and liver toxicity associated with voriconazole use.
Icelandic: - Leiðbeinir heilbrigðisstarfsfólki um hættuna á ljóseiturhrifum, flöguþekjukrabbameini í húð og eiturverkunum á lifur sem tengist notkun vórikónazóls.
English: (a maximum dose of 350 mg twice daily) Note: Based on a population pharmacokinetic analysis in 112 immunocompromised paediatricpatients aged 2 to <12 years and 26 immunocompromised adolescents aged 12 to <17 years.
Icelandic: Byggt á þýðisgreiningu á lyfjahvörfum hjá 112 ónæmisbældum börnum á aldrinum 2 til <12 ára og 26 ónæmisbældum unglingum á aldrinum 12 til <17 ára.
English: High dose (400 mg BID) Low dose (100 mg BID)*
Icelandic: Lítill skammtur (100 mg BID)*
English: Voriconazole Accord is an antifungal medicine.
Icelandic: Voriconazole Accord inniheldur virka efnið vórikónazól.
English: Cardiac disorders arrhythmia supraventricular, tachycardia, bradycardia ventricular fibrillation, ventricular extrasystoles, ventricular tachycardia, electrocardiogram QT prolonged, supraventricular tachycardia torsades de pointes, atrioventricular block complete, bundle branch block, nodal rhythm
Icelandic: Hjarta ofansleglahjartslátt arglöp (arrhythmia supraventricular), hraður hjartsláttur, hægur hjartsláttur sleglatitringur (ventricular fibrillation ), aukaslög frá sleglum (ventricular extrasystoles), sleglahraðtaktur (ventricular tachycardia), lenging á QTc-bili á hjartarafriti, ofansleglahraðtak tur (supraventricular tachycardia)
English: The species most frequently involved in causing human infections include C. albicans, C. parapsilosis, C.tropicalis, C. glabrata andC.
Icelandic: Þær tegundir sem oftast valda sýkingum hjá mönnum eru m.a. C. albicans, C. parapsilosis, C. tropicalis, C. glabrata og C. krusei, lágmarksheftistyrkur (MIC) vórikónazóls fyrir allar þessar tegundir er venjulega minni en 1 mg/l.
English: • Oral contraceptives (if you take Voriconazole Accord whilst using oral contraceptives, you may get side effects such as nausea and menstrual disorders)
Icelandic:  Getnaðarvarnarlyf til inntöku (ef þú tekur Voriconazole Accord um leið og þú tekur getnaðarvarnarlyf, geta aukaverkanir eins og ógleði og tíðatruflanir komið fram)  Vinka alkalóíðar (vincristine, vinblastine) (notaðir við krabbameini)
English: Voriconazole Accord 200 mg film-coated tablets
Icelandic: Voriconazole Accord 200 mg filmuhúðaðar töflur
English: Voriconazole Accord 50 mg film-coated tablets
Icelandic: Voriconazole Accord 50 mg filmuhúðaðar töflur
English: 300 mg QD (coadministered with voriconazole 400 mg BID)*
Icelandic: 300 mg QD (gefið samtímis vórikónazóli 400 mg BID)*
English: Although not studied, voriconazole is likely to increase the plasma concentrations of sulfonylureas and cause hypoglycaemia.
Icelandic: Þó engar rannsóknir hafi verið gerðar er líklegt að vórikónazól hækki plasmaþéttni súlfónýlúreasambanda og valdi blóðsykurslækkun.
English: MIC breakpoint (mg/L)
Icelandic: Næmismörk lágmarksheftistyrks (mg/l) ≤Næmi
English: Elderly
Icelandic: sólbruni
English: Frequent monitoring for adverse reactions and toxicity related to methadone, including QTc prolongation, is recommended when coadministered with voriconazole since methadone levels increased following coadministration of voriconazole.
Icelandic: Mælt er með reglulegu, tíðu eftirliti með auka- og eiturverkunum tengdum metadóni, þar með talið lenging á QTc bili, þegar metadón er gefið samtímis vórikónazóli þar sem metadón gildi hækka, við samtímis notkun vórikónazóls.
English: Phenytoin may be co-administered with voriconazole if the maintenance dose of voriconazole is increased to 5 mg/kg IV BID or from 200 mg to 400 mg oral BID, (100 mg to 200 mg oral BID in patients less than 40 kg) (see section 4.2).
Icelandic: Fenýtóín má gefa samtímis vórikónazóli ef viðhaldsskammtur vórikónazóls gefinn í bláæð er aukinn í 5 mg/kg BID eða skammtur til inntöku er aukinn úr 200 mg í 400 mg BID, (100 mg til 200 mg til inntöku BID hjá sjúklingum sem eru léttari en 40 kg) (sjá kafla 4.2).
English: Ritonavir (protease inhibitor)
Icelandic: skjaldvakaóhóf (hyperthyroidism
English: • Non-nucleoside reverse transcriptase inhibitors (e.g., efavirenz, delavirdine, nevirapine) (used for treating HIV) (some doses of efavirenz can NOT be taken at the same time as Voriconazole
Icelandic: HIV-smiti) (suma skammta af efavírens er EKKI hægt að taka á sama tíma og Voriconazole
English: Prednisolone (60 mg single dose)
Icelandic: Prednisólon (60 mg stakur skammtur)
English: Although not studied, voriconazole is likely to significantly increase the plasma concentrations of everolimus.
Icelandic: Þó engar rannsóknir hafi verið gerðar er líklegt að vórikónazól auki plasmaþéttni everólimus marktækt.
English: Efavirenz 300 mg QD, coadministered with voriconazole 400 mg BID*
Icelandic: Efavírenz 300 mg QD, gefið samtímis vórikónazóli 400 mg BID*
English: Phenytoin may be coadministered with voriconazole if the maintenance dose of voriconazole is increased from 200 mg to 400 mg orally, twice daily (100 mg to 200 mg orally, twice daily in patients less than 40 kg), see sections 4.4 and 4.5.
Icelandic: Gefa má fenýtóín samhliða vórikónazóli ef viðhaldsskammtur vórikónazóls er aukinn úr 200 mg í 400 mg til inntöku tvisvar sinnum á sólarhring (100 mg í 200 mg til inntöku tvisvar sinnum á sólarhring hjá sjúklingum léttari en 40 kg), sjá kafla 4.4 og 4.5.
English: Although not studied, voriconazole may increase the plasma concentrations of coumarins that may cause an increase in prothrombin time
Icelandic: Þó það hafi ekki verið rannsakað getur vórikónazól aukið plasmagildi kúmarína og með því lengt prótrombíntíma.
English: Timepoint
Icelandic: Tími
English: Stevens-Johnson syndrome, phototoxicity, purpura, urticaria, dermatitis allergic, rash papular, rash macular, eczema toxic epidermal necrolysis, angioedema, actinic keratosis*, pseudoporphyri a erythema multiforme, psoriasis, drug eruption, drug reaction with eosinophilia and systemic symptoms (DRESS)
Icelandic: Stevens-Johnson heilkenni, ljóseiturhrif, purpuri, ofsakláði, ofnæmishúðbólga , örðuútbrot, dröfnuútbrot, exem eitrunardreplos húðþekju, ofsabjúgur, geislunarhyrning regnbogaroðasótt , psóríasis, lyfjaútþot, útbrot af völdum lyfja með fjölgun rauðkyrningaog altækum einkennum (DRESS)
English: Rifabutin Cmax 195% Rifabutin AUCτ 331%
Icelandic: Rífabútín Cmax  195% Rífabútín AUC  331% Borið saman við vórikónazól 200 mg BID,
English: NAME OF THE MEDICINAL PRODUCT Voriconazole Accord 50 mg film-coated tablets Voriconazole Accord 200 mg film-coated tablets
Icelandic: Voriconazole Accord 50 mg filmuhúðaðar töflur Voriconazole Accord 200 mg filmuhúðaðar töflur
English: However, the in vitro activity of voriconazole against Candida species is not uniform.
Icelandic: Hinsvegar eru in vitro áhrif vórikónazóls ekki eins gegn öllum Candida tegundum.
English: Voriconazo le
Icelandic: Almenn lýsing
English: inflammation of the skin, hives, sunburn or severe skin reaction following exposure to light or sun, skin redness and irritation, red or purple discoloration of the skin which may be caused by low platelet count, eczema - Infusion site reaction - Allergic reaction or exaggerated immune response
Icelandic: ofsakláði, sólbruni eða alvarleg viðbrögð húðar sem ljós eða sólarljós hefur skinið á, roði og erting í húð, rauð eða fjólublá mislitun húðar sem kann að orsakast af litlum fjölda blóðflagna,
English: There are no adequate data on the use of voriconazole in pregnant women available.
Icelandic: Engar fullnægjandi upplýsingar liggja fyrir um notkun vórikónazóls á meðgöngu.
English: 200 mg twice a day
Icelandic: 200 mg tvisvar sinnum á sólarhring.
English: Phenytoin Cmax  67% Phenytoin AUCτ  81%
Icelandic: Fenýtóín Cmax  67% Fenýtóín AUC  81% Borið saman við vórikónazól 200 mg BID,
English: Success at Day 180* * Primary endpoint of study ** Using a margin of 5%, non inferiority is demonstrated *** Difference in proportions, 95% CI obtained after adjustment for randomization
Icelandic: * Aðalendapunktur rannsóknar ** Jafngildi er sýnt með 5% vikmörkum ***Mismunur í hlutföllum, á 95% öryggisbilinu sem fékkst eftir leiðréttingu fyrir slembiröðun
English: 300 mg TID (coadministered with voriconazole 400 mg single dose)
Icelandic: 300 mg TID (gefið samtímis stökum 400 mg skammti af vórikónazóli)
English: The absolute bioavailability of voriconazole after oral administration is estimated to be 96%.When multiple doses of voriconazole are administered with high fat meals, Cmax and AUCτ are reduced by 34 % and 24 %, respectively.
Icelandic: Þegar endurteknir skammtar vórikónazóls eru teknir samtímis fituríkri fæðu minnkar Cmax um 34% og AUC um 24%.
English: Transcriptase Inhibitors (NNRTIs) (e.g., delavirdine, nevirapine)*
Icelandic:  Bakritahemlar sem ekki eru núkleósíð (t.d. efavírenz, delavirdín, nevírapín) (notaðir við
English: In the clinical programme, no dosage adjustment was made on the basis of gender.
Icelandic: Í klínískum rannsóknum var skömmtum ekki breytt eftir kyni.
English: Voriconazo le (N=98)
Icelandic: Endapunktar rannsóknar Vórikónazól (N=98)
English: [CYP3A4 inhibitor and substrate]
Icelandic: [CYP3A4 hemill og hvarfefni]
English: Medicinal product
Icelandic: Markaðsleyfishafi
English: [CYP450 inducer; P-gp inducer]
Icelandic: virkir; P-gp virkir]
English: includingT.
Icelandic: Til inntöku.
English: Voriconazole is a triazole antifungal agent.
Icelandic: Voriconazole Accord er sveppalyf.
English: Careful monitoring of phenytoin levels is recommended when phenytoin is coadministered with voriconazole.
Icelandic: Hafa þarf nákvæmt eftirlit með fenýtóíngildum þegar fenýtóín er gefið samtímis vórikónazóli.
English: It is used for the treatment of patients (adults and children over the age of 2) with:
Icelandic: Ráðlagður skammtur fyrir fullorðna (þar með taldir aldraðir) er eftirfarandi:
English: tingling or burning in the hands or feet - Problems with balance or coordination - Swelling of the brain - Double vision, serious conditions of the eye including: pain and inflammation of the eyes and eyelids, abnormal eye movement, damage to the optic nerve resulting in vision impairment,
Icelandic: - Bólga í heila - Tvísýni, alvarlegt ástand á auga, þ.m.t.:verkur og bólga í augum og augnlokum, ósjálfráð hreyfing augna, óeðlileg augnhreyfing, skemmd á sjóntaug sem leiðir til sjónskerðingar, bólga í sjóntaugardoppu
English: Patients receiving Voriconazole Accord must be carefully monitored for hepatic toxicity.
Icelandic: Fylgjast þarf nákvæmlega með sjúklingum sem fá Voriconazole Accord m.t.t. til eiturverkana á lifur.
English: Phenytoin
Icelandic: P-gildi
English: It is estimated that, on average, increasing the oral dose from 200 mg twice daily to 300 mg twice daily leads to a 2.5-fold increase in exposure (AUCτ).The oral maintenance dose of 200 mg (or 100 mg for patients less than 40 kg)
Icelandic: Það er áætlað að aukning á skammti til inntöku úr 200 mg tvisvar sinnum á sólarhring í 300 mg tvisvar sinnum á sólarhring leiði að meðaltali til 2,5 faldrar aukningar á útsetningu (AUC).
English: Do not take Voriconazole Accord If you are allergic to voriconazole or any of the other ingredients of this medicine (listed in section 6).
Icelandic: Ef um er að ræða ofnæmi fyrir vórikónazóli eða einhverju öðru innihaldsefni lyfsins (talin upp í kafla 6).
English: hepatic failure, hepatomegaly, cholecystitis, cholelithiasis
Icelandic: lifrarbilun, lifrarstækkun, gallblöðrubólga, gallsteinar
English: Voriconazole Accord 200 mg film-coated tablets voriconazole
Icelandic: Voriconazole Accord 200 mg filmuhúðaðar töflur vórikónazól
English: Dosage adjustments in case of co-administration
Icelandic: - Vandamál við jafnvægi eða samhæfingu
English: Endocrine disorders adrenal insufficiency, hypothyroidism hyperthyroidis m
Icelandic: Innkirtlar skert starfsemi nýrnahettubarkar, skjaldvakabrestur (hypothyroidism)
English: Voriconazole Accord 50 mg film-coated tablets voriconazole
Icelandic: Voriconazole Accord 50 mg filmuhúðaðar töflur vórikónazól
English: Itraconazo le
Icelandic: LOTUNÚMER
English: In a study in healthy volunteers investigating the impact of voriconazole on retinal function, voriconazole caused a decrease in the electroretinogram (ERG) waveform amplitude.
Icelandic: á áhrifum vórikónazóls hjá heilbrigðum sjálfboðaliðum olli vórikónasól lækkun á bylgju á sjónurafriti (electroretinogram:ERG).
English: What Voriconazole Accord contains
Icelandic: Hvernig nota á Voriconazole Accord
English: Dose reduction of sulfonylureas should be considered
Icelandic: Hugleiða þarf hvort minnka þurfi skammt súlfónýlúreasambanda.
English: - Inflammation of the sinuses, inflammation of the gums, chills, weakness - Low numbers of some types, including severe, of red (sometimes immune-related) and/or white blood cells (sometimes with fever), low numbers of cells called platelets that help the blood to clot - Low blood sugar, low blood potassium, low sodium in the blood - Anxiety, depression, confusion, agitation, inability to sleep, hallucinations - Seizures, tremors or uncontrolled muscle movements, tingling or abnormal skin sensations,
Icelandic: - Bólga í ennis- og kinnholum, erting og bólga í meltingarvegi, kuldahrollur, slappleiki - Lítið magn, stundum hættulega lítið magn, sumra tegunda rauðra (stundum ónæmistengt) og/eða hvítra blóðkorna (stundum með hita), lítið magn frumna sem nefnast blóðflögur og hjálpa blóðinu að storkna
English: Monitoring for adverse reactions related to oral contraceptives, in addition to those for voriconazole, is recommended ol (1 mg/0.035 mg QD)
Icelandic: Noretisterón/etinýlestradíól (1 mg/0,035 mg QD)
English: Trichosporon spp.
Icelandic: til korndrjólaeitrunar.
English: Immune system disorders hypersensitivity anaphylactoid reaction
Icelandic: - Aukaverkanir á innrennslisstað - Ofnæmisviðbrögð eða óeðlilega mikil ónæmissvörun
English: The frequency of phototoxicity reactions is higher in the paediatric population.
Icelandic: Tíðni ljóseiturhrifa er hærri hjá börnum.
English: The effect of voriconazole on either erythromycin or azithromycin is unknown
Icelandic: Vórikónazól Cmax og AUC Áhrif vórikónazóls á erýtrómýsín og azitrómýsín eru óþekkt.
English: 100 mg twice a day
Icelandic: 100 mg tvisvar sinnum á sólarhring.
English: Hepatic toxicity
Icelandic: Ónæmisbælandi lyf
English: squamous cell carcinoma
Icelandic: - Kviðverkir - Öndunarerfiðleikar
English: Side effects with frequency not known: - Freckles and pigmented spots
Icelandic: Aukaverkanir þar sem tíðni er ekki þekkt:
English: 4 mg/kg twice daily
Icelandic: 4 mg/kg tvisvar sinnum á sólarhring.
English: Pharmacotherapeutic group: Antimycotics for systemic use, triazole derivatives, ATC code: J02A C03 Mode of action
Icelandic: Sveppalyf til almennrar notkunar, tríazólafleiður, ATC-flokkur:
English: Pregnancy
Icelandic: Skammtaaðlögun