FrancophonIA/ELRC3.0 huggingface dataset:
English: Switching a patient between another type or brand of insulin and Toujeo should be done under strict medical supervision.
Croatian: Prijelaz bolesnika s inzulina druge vrste ili drugog proizvođača na Toujeo treba provesti pod strogim liječničkim nadzorom.
English: Entire study period
Croatian: Cijelo razdoblje ispitivanja
English: To prevent the possible transmission of disease, insulin pens should never be used for more than one person, even when the needle is changed.
Croatian: Da bi se spriječio mogući prijenos bolesti, istu inzulinsku brizgalicu nikada ne smije koristiti više osoba, čak ni kada se zamijeni igla.
English: A Select 3 units by turning the dose selector until the dose pointer is at the mark between 2 and
Croatian: A Odaberite 3 jedinice okretanjem izbornika doze dok se pokazivač doze ne nađe na oznaci između 2 i 4.
English: Insulin label must always be checked before each injection to avoid medication errors between Toujeo and other insulins (see section 6.6).
Croatian: Prije svake injekcije uvijek se mora provjeriti naljepnica na inzulinu kako ne bi došlo do medikacijskih pogrešaka zbog zamjene lijeka Toujeo i drugih inzulina (vidjeti dio 6.6).
English: Mean dose of insulin glargine 100 units/ml by study end was 0.42 U/kg.
Croatian: Srednja doza inzulina glargina jačine 100 jedinica/ml na kraju ispitivanja bila je 0,42 jedinice/kg.
English: Incidence (%) of confirmed nocturnalc hypoglycaemia (n/Total N)
Croatian: Incidencija (%) potvrđene noćne c hipoglikemije (n/ukupan N)
English: Figure 1: Activity profile at steady state in patients with type 1 diabetes in a 36-hour euglycaemic clamp study
Croatian: Slika 1: Profil djelovanja u stanju dinamičke ravnoteže u bolesnika sa šećernom bolešću tipa 1 u 36-satnom ispitivanju uz pomoć euglikemijske spone
English: Table 3 - Summary of the hypoglycaemic episodes of the clinical study in patients with type 1 and type 2 diabetes mellitus
Croatian: Tablica 3 - Sažetak epizoda hipoglikemije u kliničkim ispitivanjima provedenima u bolesnika sa šećernom bolešću tipa 1 i tipa 2 Populacija bolesnika sa šećernom bolešću
English: In the event of blocked needle, the patients must follow the instructions described in Step 3 of the Instructions for Use accompanying the package leaflet (see section 6.6).
Croatian: U slučaju začepljenja igle, bolesnici se moraju pridržavati uputa opisanih u 3. koraku uputa za uporabu, koje dolaze zajedno s uputom o lijeku (vidjeti dio 6.6).
English: The medicinal product may be stored for a maximum of 6 weeks below 30°C and away from direct heat or direct light.
Croatian: Lijek se može čuvati najdulje 6 tjedana na temperaturi ispod 30°C, zaštićen od izvora topline i izravne svjetlosti.
English: If you use more than one insulin always ensure you use the right insulin by checking the insulin label before each injection.
Croatian: Ako koristite više od jednog inzulina, prije svake injekcije uvijek pregledajte naljepnicu na inzulinu kako biste se uvjerili da imate pravi inzulin.
English: Packs of 1, 3, 5 and 10 pens are available.
Croatian: Dostupna su pakiranja od 1, 3, 5 i 10 brizgalica.
English: The following adverse reactions were observed during clinical studies conducted with Toujeo (see section 5.1) and during clinical experience with insulin glargine 100 units/ml.
Croatian: Sljedeće su nuspojave primijećene tijekom kliničkih ispitivanja lijeka Toujeo (vidjeti dio 5.1) i tijekom primjene inzulina glargina jačine 100 jedinica/ml u kliničkoj praksi.
English: Zinc chloride, metacresol, glycerol, hydrochloric acid / sodium hydroxide (for pH adjustment), water for injections.
Croatian: Cinkov klorid, metakrezol, glicerol, kloridna kiselina / natrijev hidroksid (za prilagodbu pH), voda za injekcije.
English: DoubleStar pen:
Croatian: DoubleStar brizgalica:
English: • If you switch from another type, brand or manufacturer of insulin your insulin dose may need to be changed.
Croatian: • ako prelazite s neke druge vrste inzulina, inzulina drugog naziva ili drugog proizvođača, možda će trebati promijeniti dozu inzulina
English: This is because you will not be able to read the dose window on the pen.
Croatian: Naime, nećete moći očitati dozu na prozorčiću za prikaz doze na brizgalici.
English: If your blood sugar gets too low, see the advice in the box at the end of this leaflet.
Croatian: Ako Vam razina šećera u krvi postane preniska, pogledajte savjete u uokvirenom tekstu na kraju ove Upute.
English: [-0.090 to 0.174]
Croatian: [-0,090 do 0,174]
English: The percentage of patients with hyperglycaemic episodes with ketosis was lower for Toujeo versus insulin glargine 100 units/mL, 6.4% and 11.8%, respectively.
Croatian: Postotak bolesnika s epizodama hiperglikemije s ketozom bio je niži za lijek Toujeo naspram inzulina glargina 100 jedinica/mL i to 6,4% naspram 11,8%.
English: - That dose adjustment is needed when patients are switched from one to the other strength: After titration, on average a 10-18% higher basal insulin dose are needed to achieve target ranges for plasma glucose levels when using the 300 units/ml formulation compared to the 100 units/ml formulation.
Croatian: Nakon titracije, potrebna je u prosjeku 10-18% viša doza bazalnog inzulina da se postigne ciljni raspon koncentracije glukoze u plazmi pri upotrebi formulacije od 300 jedinica/ml u usporedbi s formulacijom od 100 jedinica/ml.
English: • Your low blood sugar comes on slowly.
Croatian: • ako razina šećera u krvi sporo pada
English: The superiority of Toujeo over insulin glargine 100 units/ml in lowering the risk of confirmed nocturnal hypoglycaemia was shown in patients with type 2 diabetes treated with basal insulin in combination with either non-insulin anti-hyperglycaemic medicinal product (18% risk reduction) or mealtime insulin (21% risk reduction) during the period from week 9 to end of study period.
Croatian: Superiornost lijeka Toujeo u odnosu na inzulin glargin jačine 100 jedinica/ml s obzirom na smanjenje rizika od potvrđene noćne hipoglikemije dokazana je u bolesnika sa šećernom bolešću tipa 2 liječenih bazalnim inzulinom u kombinaciji s neinzulinskim antihiperglikemikom (smanjenje rizika za 18%) ili inzulinom koji se primjenjuje u vrijeme obroka (smanjenje rizika za 21%) tijekom razdoblja od 9. tjedna do kraja ispitivanja.
English: Before using Toujeo SoloStar pre-filled pen or Toujeo DoubleStar pre-filled pen, the instructions for use included in the package leaflet must be read carefully (see section 6.6).
Croatian: Prije uporabe napunjene brizgalice Toujeo SoloStar ili napunjene brizgalice Toujeo DoubleStar, moraju se pažljivo pročitati upute za uporabu koje su sastavni dio upute o lijeku (vidjeti dio 6.6).
English: Packs of 1, 3, 6 (2 packs of 3), 9 (3 packs of 3) and 10 pens are available.
Croatian: Dostupna su pakiranja od 1, 3, 6 (2 pakiranja od 3), 9 (3 pakiranja od 3) i 10 brizgalica.
English: Before injecting Toujeo
Croatian: Prije nego što injicirate Toujeo
English: • Your pen contains a total of 900 units of insulin.
Croatian: • Vaša brizgalica sadrži ukupno 900 jedinica inzulina.
English: The Toujeo SoloStar and Toujeo DoubleStar pre-filled pens have been specifically designed for Toujeo and no dose re-calculation is required for either pen.
Croatian: Toujeo SoloStar i Toujeo DoubleStar napunjene brizgalice oblikovane su posebno za Toujeo i stoga nije potrebno preračunavati dozu.
English: In patients with renal impairment, insulin requirements may be diminished due to reduced insulin metabolism (see section 4.8).
Croatian: U bolesnika s oštećenjem funkcije bubrega potrebe za inzulinom mogu biti smanjene zbog usporenog metabolizma inzulina (vidjeti dio 4.8).
English: If this occurs, patients should increase the frequency of checking their blood glucose levels and might need to administer additional insulin.
Croatian: Ako se ovo dogodi, bolesnik treba povećati učestalost provjeravanja razine glukoze u krvi te će možda trebati primijeniti dodatni inzulin.
English: 450 units per pen (SoloStar pen) 900 units per pen (DoubleStar pen)
Croatian: 450 jedinica u brizgalici (SoloStar brizgalica) 900 jedinica u brizgalici (DoubleStar brizgalica)
English: Places to inject
Croatian: Mjesta za injiciranje
English: When switching from a treatment regimen with an intermediate or long-acting insulin to a regimen with Toujeo, a change of the dose of the basal insulin may be required and the concomitant anti-hyperglycaemic treatment may need to be adjusted (dose and timing of additional regular insulins or fast-acting insulin analogues or the dose of non-insulin anti-hyperglycaemic medicinal products).
Croatian: Kad se prelazi s liječenja inzulinom srednje dugog ili dugog djelovanja na liječenje lijekom Toujeo, možda će biti potrebno promijeniti dozu bazalnog inzulina i prilagoditi istodobno liječenje antihiperglikemicima (dozu i vrijeme primjene dodatnih običnih inzulina ili brzodjelujućih inzulinskih analoga odnosno dozu neinzulinskih antihiperglikemika).
English: Tell your doctor, pharmacist or nurse if you notice any of the following side effects:
Croatian: Obavijestite svog liječnika, ljekarnika ili medicinsku sestru ako primijetite bilo koju od ovih nuspojava:
English: Switch between insulin glargine 100 units/ml and Toujeo Since insulin glargine 100 units/ml and Toujeo are not bioequivalent and are not interchangeable, switching may result in the need for a change in dose and should only be done under strict medical supervision (see section 4.2).
Croatian: Prijelaz s inzulina glargina jačine 100 jedinica/ml na Toujeo Obzirom da inzulin glargin 100 jedinica/ml i Toujeo nisu bioekvivalentni i nisu međusobno zamjenjivi, prijelaz može rezultirati potrebom za promjenom doze i mora biti proveden pod strogim liječničkim nadzorom.
English: The prolonged duration of action of Toujeo is dependent on its injection into subcutaneous tissue.
Croatian: Produljeno djelovanje lijeka Toujeo ovisi o injiciranju u potkožno tkivo.
English: - When switching from insulin glargine 100 units/ml to Toujeo, this can be done on a unit-to-unit basis, but a higher Toujeo dose (approximately 10-18%) may be needed to achieve target ranges for plasma glucose levels.
Croatian: - Prijelaz s inzulina glargina 100 jedinica/ml na Toujeo može se obaviti po načelu jedinica za jedinicu, ali možda će biti potrebna veća doza lijeka Toujeo (približno 10-18%) da bi se postigle ciljne vrijednosti razine glukoze u plazmi.
English: • Serious low blood sugar may cause brain damage and may be life-threatening.
Croatian: • Ozbiljno niska razina šećera u krvi može uzrokovati oštećenje mozga te može biti opasna po život.
English: Results support the use of Toujeo in paediatric patients with type 2 diabetes mellitus.
Croatian: Rezultati podržavaju primjenu lijeka Toujeo kod pedijatrijskih bolesnika sa šećernom bolešću tipa 2.
English: In the event of blocked needle, the patients must follow the instructions described in Step 3 of the Instructions for Use accompanying the package leaflet (see section 4.2 and 4.4).
Croatian: U slučaju začepljenja igle, bolesnici se moraju pridržavati uputa opisanih u 3. koraku uputa za uporabu, koje dolaze zajedno s uputom o lijeku (vidjeti dijelove 4.2 i
English: • Your pen contains a total of 450 units of insulin.
Croatian: • Vaša brizgalica sadrži ukupno 450 jedinica inzulina.
English: The product may be stored for a maximum of 6 weeks below 30°C.
Croatian: Lijek se može čuvati najdulje 6 tjedana na temperaturi ispod 30°C.
English: • You change the area of skin where you inject insulin.
Croatian: • ako promijenite područje na koži u koje injicirate inzulin, npr. injicirate u nadlakticu umjesto u bedro
English: Toujeo is for subcutaneous use only.
Croatian: Toujeo je namijenjen samo za supkutanu primjenu.
English: The pen may be stored for a maximum of 6 weeks below 30°C and away from direct heat or direct light.
Croatian: Brizgalice se mogu čuvati najdulje 6 tjedana na temperaturi ispod 30°C, zaštićene od izvora topline i izravne svjetlosti.
English: See “Pioglitazone used together with insulin”.
Croatian: Pogledajte odlomak 'Pioglitazon u kombinaciji s inzulinom'
English: If you do you will get too much insulin.
Croatian: U protivnom ćete primijeniti previše inzulina.
English: • You are taking or have taken certain other medicines (see section 2, "Other medicines and
Croatian: • uzimate ili ste uzimali neke druge lijekove (pogledajte odlomak 'Drugi lijekovi i Toujeo' u dijelu 2.)
English: • You are taking or have stopped taking certain other medicines (see section 2, "Other medicines and Toujeo").
Croatian: • uzimate ili ste prestali uzimati neke druge lijekove (pogledajte odlomak 'Drugi lijekovi i Toujeo' u dijelu 2.)
English: Packs of 1, 3, 6 (2 packs of 3), 9 (3 packs of 3) and 10 pre-filled pens.
Croatian: Dostupna su pakiranja od 1, 3, 6 (2 pakiranja od 3), 9 (3 pakiranja od 3) i 10 napunjenih brizgalica.
English: To ensure the pen and needle are working, always perform the safety test until you see insulin coming out the needle tip before each injection (see STEP 3).
Croatian: Kako biste osigurali da su brizgalica i igla ispravne, uvijek napravite test sigurnosti prije svakog injiciranja dok ne vidite da inzulin izlazi kroz vrh igle (vidjeti 3. KORAK).
English: Please, see also section 3.
Croatian: Također, pogledajte dio 3.
English: To prevent possible transmission of disease, insulin pens should never be used for more than one person, even when the needle is changed (see section 6.6).
Croatian: Kako bi se spriječio mogući prijenos bolesti, istu inzulinsku brizgalicu nikada ne smije koristiti više osoba, čak ni kada se zamijeni igla (vidjeti dio 6.6).
English: This is because this medicine lowers your blood sugar over a long period of time (for more information, see section 3).
Croatian: Ako je potrebno, možete promijeniti vrijeme injekcije jer ovaj lijek snizuje razinu šećera u krvi tijekom duljeg razdoblja (za više informacija pogledajte dio 3.).
English: If this happens: - change the needle (see STEP 6 and STEP 2), - then repeat the safety test (STEP 3A and STEP 3 B).
Croatian: U tom slučaju: - zamijenite iglu (pogledajte 6. KORAK i 2. KORAK), - zatim ponovite test sigurnosti (3. KORAK).
English: If you stop using Toujeo
Croatian: Ako prestanete primjenjivati Toujeo
English: EU/1/00/133/039 6 pens (2 packs of 3) EU/1/00/133/040 9 pens (3 packs of 3)
Croatian: EU/1/00/133/040 9 brizgalica (3 pakiranja od 3)
English: In Toujeo clinical studies in adult patients, the incidence of allergic reactions was similar in Toujeo-treated patients (5.3%) and insulin glargine 100 units/ml-treated patients (4.5%).
Croatian: U kliničkim ispitivanjima lijeka Toujeo provedenima u odraslih bolesnika, incidencija alergijskih reakcija bila je slična u bolesnika liječenih lijekom Toujeo (5,3%) i onih liječenih inzulinom glarginom jačine 100 jedinica/ml (4,5%).
English: Results from all clinical trials with Toujeo indicated that reductions in HbA1c from baseline to end of trial were non-inferior to insulin glargine 100 units/ml.
Croatian: Rezultati svih kliničkih ispitivanja lijeka Toujeo pokazali su da su sniženja razine HbA1c od početne vrijednosti do kraja ispitivanja bila neinferiorna u odnosu na inzulin glargin jačine 100 jedinica/ml.
English: - Switching from twice-daily basal insulins to once-daily Toujeo, the recommended initial Toujeo dose is 80% of the total daily dose of basal insulin that is being discontinued.
Croatian: - Pri prijelazu s bazalnih inzulina koji se primjenjuju dvaput na dan na liječenje lijekom Toujeo jedanput na dan, preporučena početna doza lijeka Toujeo je 80% ukupne dnevne doze bazalnog inzulina koji se prestaje primjenjivati.
English: Flexibility in time of administration
Croatian: Fleksibilno vrijeme primjene
English: It delivers doses of 1-80 units per injection, in steps of 1 unit.
Croatian: Isporučuje doze od 1-80 jedinica po injekciji, u koracima od 1 jedinice.
English: • When insulin comes out of the needle tip, your pen is working correctly.
Croatian: • Ako inzulin izlazi kroz vrh igle, Vaša brizgalica radi ispravno.
English: What you need to know before you use Toujeo Do not use Toujeo
Croatian: Što morate znati prije nego počnete primjenjivati Toujeo
English: Packs of 1, 3, 5 and 10 pre-filled pens.
Croatian: Dostupna su pakiranja od 1, 3, 5 i 10 napunjenih brizgalica.
English: Pioglitazone used together with insulin
Croatian: Pioglitazon u kombinaciji s inzulinom
English: Toujeo lowers your blood sugar steadily over a long period of time.
Croatian: Toujeo polako snizuje razinu šećera u krvi tijekom duljeg razdoblja.
English: Please, see also section 2.
Croatian: Također pogledajte dio 2.
English: 58 units selected
Croatian: odabrano je 60 jedinica odabrano je 58 jedinica
English: Plasma glucose reductions at the end of the trial with Toujeo were similar to insulin glargine 100 units/ml with a more gradual reduction during the titration period with Toujeo.
Croatian: Sniženja razine glukoze u plazmi na kraju ispitivanja postignuta uz Toujeo bila su slična onima postignutima uz inzulin glargin jačine 100 jedinica/ml, ali je smanjenje tijekom razdoblja titracije bilo postupnije uz Toujeo.
English: 900 units per pen
Croatian: 900 jedinica u brizgalici
English: At the last on-treatment visit, there was a mean increase in body weight from baseline of 1.4 kg in the insulin glargine 100 units/ml group and a mean decrease of 0.8 kg in the standard care group.
Croatian: Pri posljednjoj kontroli tijekom liječenja zabilježeno je srednje povećanje tjelesne težine od 1,4 kg u odnosu na početnu vrijednost u skupini koja je primala inzulin glargin jačine 100 jedinica/ml te srednje smanjenje od 0,8 kg u odnosu na početnu vrijednost u skupini koja je primala standardno liječenje.
English: Meal-time insulin analog Meal-time insulin analog+/-metformin
Croatian: Inzulinski analog koji se primjenjuje u vrijeme obroka +/-metformin
English: Toujeo is administered subcutaneously by injection in the abdominal wall, the deltoid or the thigh.
Croatian: Toujeo se primjenjuje supkutanom injekcijom u trbušnu stijenku, deltoidni mišić ili bedro.
English: Serious low blood sugar may cause brain damage and may be life-threatening.
Croatian: Ozbiljno niska razina šećera u krvi može uzrokovati oštećenje mozga te može biti opasna po život.
English: Patients previously treated with basal insulin
Croatian: Bolesnici prethodno liječeni bazalnim inzulinom
English: Effects of insulin glargine 100 units/ml (once daily) on diabetic retinopathy were evaluated in an open-label 5 year NPH-controlled study (NPH given bid) in 1024 type 2 diabetic patients in which progression of retinopathy by 3 or more steps on the Early Treatment Diabetic Retinopathy Study (ETDRS) scale was investigated by fundus photography.
Croatian: Učinak inzulina glargina jačine 100 jedinica/ml (primijenjenog jedanput dnevno) na dijabetičku retinopatiju ocijenjen je u 5-godišnjem otvorenom kliničkom ispitivanju kontroliranom NPH inzulinom (NPH primijenjen dvaput na dan) u 1024 bolesnika sa šećernom bolešću tipa 2, u kojih je progresija retinopatije za više od 3 stupnja na ljestvici ETDRS (ispitivanje ranog liječenja dijabetičke retinopatije; engl.
English: To prevent possible transmission of disease, insulin pen should never be used by for more than one person, even when the needle is changed (see section 4.2).
Croatian: Da bi se spriječio mogući prijenos bolesti, istu inzulinsku brizgalicu nikada ne smije koristiti više osoba, čak ni kada se zamijeni igla (vidjeti dio 4.2).
English: If you see insulin coming out the needle tip, the pen is ready to use.
Croatian: Ako vidite da inzulin izlazi kroz vrh igle, brizgalica je spremna za korištenje.
English: If you experience signs of heart failure such as unusual shortness of breath, a rapid increase in weight or localised swelling (oedema).
Croatian: Ako primijetite znakove srčanog zatajivanja, kao što su neuobičajen nedostatak zraka, naglo povećanje tjelesne težine ili lokalizirano oticanje (edem), obavijestite svog liječnika o tome što je prije moguće.
English: This medicine contains less than 1 mmol (23 mg) sodium per dose.
Croatian: Važne informacije o nekim sastojcima lijeka Toujeo Ovaj lijek sadrži manje od 1 mmol (23 mg) natrija po dozi, tj. zanemarive količine natrija.
English: The MAH shall agree the final text and the context of the educational material for HCPs and patients together with a communication plan, with the National Competent Authority in each Member State prior to launch of the medicinal product.
Croatian: Prije stavljanja lijeka u promet nositelj odobrenja dogovorit će s nadležnim nacionalnim tijelom konačni tekst i sadržaj edukacijskog materijala za zdravstvene djelatnike i bolesnike zajedno s planom komunikacije u svakoj državi članici.
English: Close metabolic monitoring is recommended during the switch and in the initial weeks thereafter;
Croatian: Pažljivo metaboličko praćenje je preporučeno tijekom prijelaza te u prvim tjednima nakon prijelaza;
English: Toujeo dosed once daily showed similar reduction in HbA1c and FPG from baseline to week 26 compared to insulin glargine 100 units/mL.
Croatian: Lijek Toujeo u dozi jedanput na dan pokazao je slično sniženje HbA1c i glukoze natašte od početnih vrijednosti do 26-og tjedna u usporedbi s inzulinom glarginom 100 jedinica/ml.
English: Medication errors due to mix-up between insulins, particularly between longacting insulins and rapid-acting insulins have been reported.
Croatian: Prijavljene su medikacijske pogreške zbog zamjene inzulina, osobito dugodjelujućih inzulina i brzodjelujućih inzulina.
English: • Do not put the pen back in the fridge.
Croatian: • Nemojte vraćati brizgalicu u hladnjak.
English: The dose increment in Toujeo SoloStar is one unit and the dose increment in Toujeo DoubleStar is 2 units.
Croatian: Odmjerni korak doze u Toujeo SoloStaru je jedna jedinica, a u Toujeo DoubleStaru 2 jedinice.
English: Incidence (%) of confirmedb hypoglycaemia (n/Total N)
Croatian: Incidencija (%) potvrđene b hipoglikemije (n/ukupan N)
English: Treatment in combination with
Croatian: Lijek u kombiniranoj primjeni
English: When switching from a treatment regimen with an intermediate or long-acting insulin product to a regimen with Toujeo, a change of the dose of the basal insulin may be required and the concomitant anti-hyperglycaemic treatment may need to be adjusted.
Croatian: Pri prijelazu s režima liječenja srednje ili dugodjelujućim inzulinom na režim liječenja lijekom Toujeo, promjena doze bazalnog inzulina može biti potrebna te može biti potrebno prilagoditi konkomitantno liječenje antihiperglikemijskim lijekovima.
English: Combination of Toujeo with pioglitazone
Croatian: Kombinacija lijeka Toujeo i pioglitazona
English: • For more information, see the box at the end of this leaflet.
Croatian: • Za više informacija pogledajte uokviren tekst na kraju ove Upute.
English: • Swelling in the calves and ankles, caused by temporary build-up of water in the body.
Croatian: Uzrokuje ga privremeno nakupljanje vode u tijelu.
English: It delivers doses of 2-160 units per injection, in steps of 2 units.
Croatian: Isporučuje doze od 2-160 jedinica po injekciji, u koracima od 2 jedinice.
English: A syringe must never be used to withdraw Toujeo from the cartridge of the pre-filled pen or severe overdose can result (see section 4.2, 4.4 and 4.9).
Croatian: Toujeo se nikada ne smije izvlačiti iz uloška napunjene brizgalice u štrcaljku jer u protivnom može doći do teškog predoziranja (vidjeti dijelove 4.2, 4.4 i 4.9).
English: Always keep the cap on the pen when you are not using it in order to protect from light.
Croatian: Kada ne koristite brizgalicu, uvijek na njoj držite zatvarač radi zaštite od svjetlosti.
English: Toujeo must not be drawn from the cartridge of the Toujeo SoloStar pre-filled pen or Toujeo DoubleStar pre-filled pen into a syringe or severe overdose can result (see section 4.4, 4.9 and 6.6).
Croatian: Toujeo se ne smije izvlačiti iz uloška napunjene brizgalice Toujeo SoloStar ili napunjene brizgalice Toujeo DoubleStar u štrcaljku jer u protivnom može doći do teškog predoziranja (vidjeti dijelove 4.4, 4.9 i 6.6).