FrancophonIA/ELRC3.0 huggingface dataset:
English: NovoEight 2000 IU powder for solution for injection turoctocog alfa
Slovenian: NovoEight 2000 i.e. prašek za raztopino za injiciranje turoktokog alfa za intravensko uporabo
English: NovoEight 3000 IU powder for solution for injection turoctocog alfa
Slovenian: NovoEight 3000 i.e. prašek za raztopino za injiciranje turoktokog alfa za intravensko uporabo
English: NovoEight 1500 IU powder for solution for injection turoctocog alfa
Slovenian: NovoEight 1500 i.e. prašek za raztopino za injiciranje turoktokog alfa za intravensko uporabo
English: Uncommonb
Slovenian: • omotica
English: Unscrew the vial adapter with the vial.
Slovenian: • Odvijte nastavek za vialo skupaj z vialo.
English: NovoEight 500 IU powder for solution for injection turoctocog alfa
Slovenian: NovoEight 500 i.e. prašek za raztopino za injiciranje turoktokog alfa za intravensko uporabo
English: 1 vial with NovoEight powder 1 vial adapter
Slovenian: • 1 vialo s praškom zdravila NovoEight,
English: One ml of NovoEight contains approximately 62.5 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 62,5 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: Store the reconstituted product in the vial.
Slovenian: Pripravljeno zdravilo shranite v viali.
English: (slightly unclear).
Slovenian: (pod pokrovčkom brizge)
English: One ml of NovoEight contains approximately 375 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 375 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: Table 4 Single-dose pharmacokinetic parameters of NovoEight (50 IU/kg) by age - one stage clotting assay - Mean (SD)
Slovenian: Farmakokinetični parametri enkratnega odmerka zdravila NovoEight (50 i.e./kg) glede na starost - enostopenjski preizkus strjevanja - povprečje (SD)
English: NovoEight 2000 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 2000 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: - The active substance is turoctocog alfa (human coagulation factor VIII (rDNA)).
Slovenian: Kaj vsebuje zdravilo NovoEight - Učinkovina je turoktokog alfa (humani koagulacijski faktor VIII (rDNA)).
English: NovoEight 250 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 250 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: NovoEight 1000 IU powder for solution for injection turoctocog alfa
Slovenian: NovoEight 1000 i.e. prašek za raztopino za injiciranje turoktokog alfa za intravensko uporabo
English: NovoEight contains turoctocog alfa, a human coagulation factor VIII (rDNA), with a truncated Bdomain.
Slovenian: Turoktokog alfa (humani koagulacijski faktor VIII (rDNA)) je prečiščen protein s
English: NovoEight 500 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 500 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: One ml of NovoEight contains approximately 125 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 125 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: NovoEight 2000 IU EU/1/13/888/005
Slovenian: ŠTEVILKE DOVOLJENJ ZA PROMET EU/1/13/888/005
English: United Kingdom
Slovenian: Danska
English: NovoEight 3000 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 3000 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: One ml of NovoEight contains approximately 750 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 750 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: On-demand treatment
Slovenian: aplikaciji zdravila
English: Life threatening haemorrhages
Slovenian: smrtno nevarne krvavitve
English: NovoEight 1500 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 1500 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: NovoEight 1000 IU powder and solvent for solution for injection turoctocog alfa (human coagulation factor VIII (rDNA))
Slovenian: NovoEight 1000 i.e. prašek in vehikel za raztopino za injiciranje turoktokog alfa (humani koagulacijski faktor VIII (rDNA))
English: (bromobutyl) and a syringe cap with a stopper (bromobutyl) - 1 plunger rod (polypropylene).
Slovenian: - 1 nosilec bata (polipropilen).
English: Wide top end
Slovenian: Minimum; maksimum
English: One ml of NovoEight contains approximately 500 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 500 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: One ml of NovoEight contains approximately 250 IU of human coagulation factor VIII (rDNA), turoctocog alfa after reconstitution
Slovenian: En mililiter zdravila NovoEight vsebuje po pripravi približno 250 i.e. humanega koagulacijskega faktorja VIII (rDNA) (turoktokog alfa).
English: Rash, lichenoid keratosis, skin burning sensation
Slovenian: Bolezni kože in podkožja pogosti izpuščaj, eritematozni izpuščaj občasni izpuščaj, lihenoidna keratoza, pekoč občutek na koži
English: Haemarthrosis, Muscle haemorrhage
Slovenian: zaščitni papir pokrovček brizge konica brizge
English: • fever
Slovenian: • bruhanje
English: Table 7 Single-dose pharmacokinetic parameters of NovoEight (50 IU/kg) by BMI classesaChromogenic assay - Mean (SD)
Slovenian: Farmakokinetični parametri enkratnega odmerka zdravila NovoEight (50 i.e./kg) glede na skupine ITMa - kromogeni preizkus - povprečje (SD)
English: STATEMENT OF ACTIVE SUBSTANCE
Slovenian: NAVEDBA UČINKOVINE
English: Table 6 Single-dose pharmacokinetic parameters of NovoEight (50 IU/kg) by BMI classesaOne-stage clotting assay - Mean (SD)
Slovenian: Farmakokinetični parametri enkratnega odmerka zdravila NovoEight (50 i.e./kg) glede na skupine ITMa - enostopenjski preizkus strjevanja - povprečje (SD)
English: NovoEight 3000 IU EU/1/13/888/006
Slovenian: ŠTEVILKE DOVOLJENJ ZA PROMET EU/1/13/888/006
English: What NovoEight is and what it is used for What you need to know before you use NovoEight How to use NovoEight
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo NovoEight
English: FVIII inhibition
Slovenian: hipotenzijo in anafilaksijo.
English: Plunger rod
Slovenian: OVOJNINAH Viala
English: Do not wait until the next planned cycle.
Slovenian: Ne čaka se do naslednjega načrtovanega cikla.
English: Your doctor will discuss this with you.
Slovenian: Vaš zdravnik se bo o tem pogovoril z vami.
English: Appropriate aseptic technique should be used.
Slovenian: Uporabiti je treba ustrezno aseptično tehniko.
English: Allow the vial to stand undisturbed for approximately 5 minutes.
Slovenian: Pustite stati vialo pri miru približno 5 minut.
English: If not used immediately, in-use storage times and conditions are the responsibility of the user.
Slovenian: Če zdravila ne uporabite takoj, so čas in pogoji shranjevanja odgovornost uporabnika.
English: Not known: frequency cannot be estimated from the available data
Slovenian: Neznana pogostnost: pogostnosti iz razpoložljivih podatkov ni mogoče oceniti
English: Children and adolescents Trazimera is not recommended for anyone under the age of 18 years.
Slovenian: Otroci in mladostniki Zdravilo Trazimera ni priporočljivo za mlajše od 18 let.
English: 88397 Biberach an der Riss Germany
Slovenian: 88397 Biberach an der Riss Nemčija
English: For intravenous/I.V.
Slovenian: za intravensko/i.v.
English: One vial contains either:
Slovenian: Ena viala vsebuje:
English: • Your doctor will advise you of the risks and benefits of taking Trazimera during pregnancy.
Slovenian: • Zdravnik vam bo svetoval glede tveganja in koristi uporabe zdravila Trazimera v času nosečnosti.
English: Clinical experience is limited in patients above 65 years of age.
Slovenian: Klinične izkušnje pri bolnikih, starejših od 65 let, so omejene.
English: This helps your medicine work as well as it can.
Slovenian: To vašemu zdravilu omogoči, da deluje kar najbolj učinkovito.
English: This could be more serious if you are already breathless.
Slovenian: Težave so lahko resnejše, če že težko dihate.
English: The bioactivity of D7D and the clinical impact of the elevation of this metabolite was unclear.
Slovenian: Biološka aktivnost D7D in klinični vpliv zaradi povišanja ravni tega presnovka nista bila jasna.
English: Your doctor will prescribe a dose and treatment regimen that is right for you.
Slovenian: Vaš zdravnik vam bo predpisal odmerek in režim zdravljenja, ki bo primeren za vas.
English: In other situations, the decision on the need for additional cytotoxic chemotherapy is determined based on individual factors.
Slovenian: V drugih primerih odločitev glede potrebe po dodatni citotoksični kemoterapiji temelji na dejavnikih posameznika.
English: 4.7 Effects on ability to drive and use machines
Slovenian: 4.7 Vpliv na sposobnost vožnje in upravljanja strojevi
English: Volume of sterile water for injections
Slovenian: Volumen sterilne vode za injekcije
English: The product is not intended to be stored after reconstitution and dilution unless this has taken place under controlled and validated aseptic conditions.
Slovenian: Zdravilo ni namenjeno shranjevanju po rekonstituciji in redčenju, razen če je to potekalo v kontroliranih in validiranih aseptičnih pogojih.
English: Total pathological complete response
Slovenian: Skupni popolni patološki odgovor
English: All doses should be taken at the right time every week or every three weeks (depending on your dosing schedule).
Slovenian: Vse odmerke morate prejeti v ustreznem času vsak teden ali vsake 3 tedne (glede na vašo shemo odmerjanja).
English: The presence of trastuzumab in the serum of infant monkeys was not associated with any adverse effects on their growth or development from birth to 1 month of age.
Slovenian: Prisotnost trastuzumaba v serumu opičjih mladičev ni bila povezana z nobenimi neželenimi učinki na njihovo rast ali razvoj od rojstva do 1 meseca starosti.
English: Trazimera can cause breathing difficulties, especially when it is first given.
Slovenian: Zdravilo Trazimera lahko povzroči težave z dihanjem, še zlasti, ko ga prejmete prvič.
English: The primary endpoint was overall survival which was defined as the time from the date of randomization to the date of death from any cause.
Slovenian: Primarni opazovani dogodek v preskušanju je bilo celokupno preživetje, ki so ga definirali kot čas od dneva randomizacije do dneva smrti iz kateregakoli vzroka.
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached.
Slovenian: • ob vsakršni spremembi sistema za obvladovanje tveganj, zlasti kadar je tovrstna sprememba posledica prejema novih informacij, ki lahko privedejo do znatne spremembe razmerja med koristmi in tveganji, ali kadar je ta sprememba posledica tega, da je bil dosežen pomemben mejnik (farmakovigilančni ali povezan z zmanjševanjem tveganja)
English: For monotherapy, the rate was 6% - 9%.
Slovenian: Za monoterapijo je bil ta odstotek 6-9 %.
English: Patients should be warned of the possibility of such a late onset and should be instructed to contact their physician if these symptoms occur.
Slovenian: Bolnike je treba opozoriti na možnost tako poznega pojava simptomov in jim svetovati, naj takoj obvestijo svojega zdravnika, če se ti simptomi pojavijo.
English: Your doctor will closely supervise your therapy.
Slovenian: Vaš zdravnik bo pozorno spremljal vaše zdravljenje.
English: In this section, the following categories of frequency have been used: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000), not known (cannot be estimated from the available data).
Slovenian: V tem poglavju so neželeni učinki navedeni po pogostnosti na naslednji način: zelo pogosti ( 1/10), pogosti ( 1/100 do < 1/10), občasni ( 1/1.000 do < 1/100), redki ( 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: TTP = time to progression; "ne" indicates that it could not be estimated or it was not yet reached.
Slovenian: TTP = čas do napredovanja bolezni (time to progression); ''no'' = ni bilo mogoče oceniti ali pa še ni bilo doseženo; IZ = interval zaupanja
English: Your doctor will monitor your heart regularly during and after treatment but you should tell your doctor immediately if you notice any of the above symptoms.
Slovenian: Vaš zdravnik bo med zdravljenjem in po njem redno nadzoroval vaše srce, vendar kljub temu nemudoma obvestite svojega zdravnika, če opazite kateregakoli od zgoraj naštetih simptomov.
English: • low counts of red blood cells and white blood cells (which help fight infection) sometimes with fever
Slovenian: • majhno število rdečih in belih krvnih celic (ki pomagajo v boju proti okužbi), včasih s povišano telesno temperaturo
English: What you need to know before you are given Trazimera
Slovenian: Kaj morate vedeti, preden boste prejeli zdravilo Trazimera
English: Infusion reactions, allergic-like reactions and hypersensitivity It is estimated that approximately 40% of patients who are treated with trastuzumab will experience some form of infusion-related reaction.
Slovenian: Infuzijske reakcije, alergiji podobne reakcije in preobčutljivost Ocenjujejo, da se pri približno 40 % bolnikov, ki prejemajo trastuzumab, pojavi neka oblika z infuzijo povezane reakcije.
English: Interruption or slowing the rate of the infusion may help control such symptoms.
Slovenian: Prekinitev ali upočasnitev hitrosti infundiranja lahko pomaga pri nadzoru teh simptomov.
English: Such methods must clearly be precise and accurate enough to demonstrate overexpression of HER2 and must be able to distinguish between moderate (congruent with 2+) and strong (congruent with 3+) overexpression of HER2.
Slovenian: Te metode morajo biti dovolj natančne in točne, da pokažejo čezmerno izražanje HER2 ter ločijo med zmernim (skladno z 2+) in močnim (skladno s 3+) čezmernim izražanjem HER2.
English: Trazimera should only be given by a doctor or nurse.
Slovenian: Zdravilo Trazimera lahko daje le zdravnik ali medicinska sestra.
English: HER2 testing must be performed in a specialised laboratory which can ensure adequate validation of the testing procedures (see section 5.1).
Slovenian: Testiranje na HER2 je treba opraviti v specializiranem laboratoriju, ki lahko zagotovi ustrezno validacijo postopkov testiranja (glejte poglavje 5.1).
English: These effects mainly occur with the first intravenous infusion (“drip” into your vein) and during the first few hours after the start of the infusion.
Slovenian: Ti učinki se pojavijo predvsem med prvo intravensko infuzijo (''kapljanjem'' zdravila v žilo) in v prvih nekaj urah po pričetku infuzije.
English: The dose of Trazimera depends on your body weight.
Slovenian: Odmerek zdravila Trazimera je odvisen od vaše telesne mase.
English: Slight foaming of the product upon reconstitution is not unusual.
Slovenian: Rahlo penjenje zdravila po rekonstituciji ni neobičajno.
English: Serious reactions have been treated successfully with supportive therapy such as oxygen, beta- agonists, and corticosteroids.
Slovenian: Resne reakcije so uspešno zdravili s podpornim zdravljenjem, kot so kisik, beta agonisti in kortikosteroidi.
English: Trazimera is for intravenous use.
Slovenian: Zdravilo Trazimera je za intravensko uporabo.
English: The results of these simulations indicate that at least 95% of patients will reach concentrations that are <1 μg/mL (approximately 3% of the population predicted Cmin,ss, or about 97% washout) by 7 months.
Slovenian: Rezultati teh simulacij kažejo, da bo najmanj 95 % bolnikov do 7. meseca doseglo koncentracije < 1 μg/ml (približno 3 % Cmin, ss, predvidene za populacijo, ali približno 97 % izpiranje).
English: All the terms included are based on the highest percentage seen in pivotal clinical trials.
Slovenian: Vsi navedeni neželeni učinki temeljijo na najvišjem odstotku, ki so ga opazili v ključnih kliničnih preskušanjih.
English: To ensure accurate and reproducible results, the testing must be performed in a specialised laboratory, which can ensure validation of the testing procedures.
Slovenian: Za zagotovitev točnih in ponovljivih rezultatov je treba testiranje opraviti v specializiranem laboratoriju, ki lahko zagotovi validacijo postopkov testiranja.
English: There is no relevant use of Trazimera in the paediatric population.
Slovenian: Uporaba zdravila Trazimera pri pediatrični populaciji ni smiselna.
English: • you have ever had or are currently using a medicine called doxorubicin or epirubicin (medicines used to treat cancer).
Slovenian: • prejemate ali ste kadarkoli prejeli zdravilo, ki se imenuje doksorubicin ali epirubicin (zdravili, ki ju uporabljamo za zdravljenje raka).
English: FP + H: Fluoropyrimidine/cisplatin + trastuzumab FP: Fluoropyrimidine/cisplatin Odds ratio
Slovenian: FP+H: fluoropirimidin/cisplatin + trastuzumab FP: fluoropirimidin/cisplatin razmerje obetov
English: Once the infusion is prepared it should be administered immediately.
Slovenian: Ko je infuzija pripravljena, jo je treba takoj infundirati.
English: If you develop any signs of heart failure (inadequate pumping of blood by the heart), your heart function may be checked more frequently (every six to eight weeks), you may receive treatment for heart failure or you may have to stop Trazimera treatment.
Slovenian: Če se bodo pri vas pojavili kakršnikoli znaki srčnega popuščanja (to je, da vaše srce ne črpa krvi v zadostni meri), bo zdravnik delovanje vašega srca preveril pogosteje (vsakih 6 do 8 tednov); morda boste prejeli zdravila proti srčnemu popuščanju ali pa boste morali prekiniti zdravljenje z zdravilom Trazimera.
English: Patients classified as staining 2+ or 3+ were included, while those staining 0 or 1+ were excluded.
Slovenian: Bolnike z vrednostjo 2+ ali 3+ so vključili v preskušanje, tiste z 0 ali 1+ pa izključili.
English: For storage conditions of the reconstituted medicinal product, see sections 6.3 and 6.6.
Slovenian: Za pogoje shranjevanja po rekonstituciji zdravila glejte poglavji 6.3 in 6.6.
English: Some of these symptoms can be serious and some patients have died (see section 2 under “Warnings and precautions”).
Slovenian: Nekateri od teh simptomov so lahko resni, poročali so o smrtnih primerih (glejte poglavje 2, ''Opozorila in previdnostni ukrepi'').
English: In order to improve the traceability of biological medicinal products, the trade name and the batch number of the administered product should be clearly recorded.
Slovenian: Za izboljšanje sledljivosti bioloških zdravil je treba jasno zabeležiti zaščiteno ime in številko serije uporabljenega zdravila.
English: These tissues were fixed in formalin or Bouin's fixative.
Slovenian: Tkiva so fiksirali s formalinom ali v Bouinsovem fiksativu.
English: Do not use this medicine after the expiry date which is stated on the outer carton and on the vial label after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na nalepki na viali poleg oznake ''EXP''.
English: However, trastuzumab may elevate the overall exposure of one doxorubicin metabolite, (7-deoxy-13 dihydro-doxorubicinone, D7D).
Slovenian: Trastuzumab lahko poveča celokupno izpostavljenost enemu metabolitu doksorubicina (7-deoksi-13- dihidro-doksorubicinonu, D7D).
English: Initial improvement followed by clinical deterioration and delayed reactions with rapid clinical deterioration have also been reported.
Slovenian: Poročali so tudi o primerih začetnega izboljšanja, ki mu je sledilo klinično poslabšanje, in primerih zapoznelih reakcij s hitrim kliničnim poslabšanjem.
English: What Trazimera is and what it is used for
Slovenian: Kaj je zdravilo Trazimera in za kaj ga uporabljamo
English: • If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before taking this medicine.
Slovenian: • Če ste noseči, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro, preden vzamete to zdravilo.
English: There was a correlation between shed antigen and SGOT/AST levels; part of the impact of shed antigen on clearance may have been explained by SGOT/AST levels.
Slovenian: Obstajala je povezava med odcepljenim antigenom in vrednostmi SGOT/AST; del vpliva odcepljenega antigena na očistek bi bilo mogoče pojasniti z vrednostmi SGOT/AST.
English: The efficacy results from the BCIRG 006 are summarized in Tables 9 and 10.
Slovenian: Rezultati učinkovitosti iz preskušanja BCIRG 006 so povzeti v preglednicah 9 in 10.
English: In the adjuvant treatment setting, trastuzumab was investigated in 4 large multicentre, randomised, trials.
Slovenian: Pri adjuvantnem zdravljenju so trastuzumab proučevali v 4 obsežnih, multicentričnih, randomiziranih preskušanjih:
English: The difference was not statistically significant, however more than half of the patients in the anastrozole alone arm crossed over to a trastuzumab containing regimen after progression of disease.
Slovenian: Razlika ni bila statistično pomembna, vendar pa je več kot polovica bolnic iz skupine, ki je prejemala le anastrozol, po napredovanju bolezni prešla na shemo, ki je vsebovala trastuzumab.
English: Doses up to this level were well tolerated.
Slovenian: Odmerke do te velikosti so bolniki dobro prenašali.
English: If a pregnant woman is treated with trastuzumab, or if a patient becomes pregnant while receiving trastuzumab or within 7 months following the last dose of trastuzumab, close monitoring by a multidisciplinary team is desirable.
Slovenian: Če se noseča ženska zdravi s trastuzumabom ali če bolnica zanosi med zdravljenjem s trastuzumabom ali v obdobju 7 mesecev po prejemu zadnjega odmerka trastuzumaba, je zaželeno, da jo skrbno spremlja multidisciplinarna ekipa.
English: If during treatment you experience symptoms, such as chills or fever, you should not drive or use machines until these symptoms disappear.
Slovenian: Če se vam med zdravljenjem pojavijo simptomi, kot je mrzlica ali zvišana telesna temperatura, ne smete voziti ali upravljati strojev, dokler ti simptomi ne izginejo.
English: Tell your doctor, pharmacist or nurse if you are taking, have recently taken or may take any other medicines.
Slovenian: Obvestite zdravnika, farmacevta ali medicinsko sestro, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katerokoli drugo zdravilo.
English: These medicines (or any other anthracyclines) can damage heart muscle and increase the risk of heart problems with Trazimera.
Slovenian: Ta zdravila (ali katerikoli antraciklin) lahko poškodujejo srčno mišico in povečajo tveganje za nastanek težav s srcem pri uporabi zdravila Trazimera;
English: If the first dose is well tolerated the next doses may be given over 30 minutes (see section 2 under “Warnings and precautions”).
Slovenian: Če boste začetni odmerek dobro prenašali, boste nadaljnje odmerke prejeli v 30 minutah (glejte poglavje 2, ''Opozorila in previdnostni ukrepi'').