FrancophonIA/ELRC3.0 huggingface dataset:
English: Hepatitis: Anti-rheumatic therapies have been associated with hepatitis B reactivation.
Croatian: Hepatitis: Primjena antireumatskih lijekova povezuje se s ponovnim aktiviranjem hepatitisa B.
English: Patients treated with ORENCIA may receive concurrent vaccinations, except for live vaccines.
Croatian: Bolesnici liječeni lijekom ORENCIA mogu istodobno primati cijepljenja, osim živim cjepivima.
English: Allergic reactions may occur after the use of ORENCIA.
Croatian: Nakon primjene lijeka ORENCIA mogu se pojaviti alergijske reakcije.
English: Most recent:
Croatian: Posljednja primjena:
English: Patients had active PsA (≥ 3 swollen joints and ≥ 3 tender joints) despite prior treatment with DMARD therapy and had one qualifying psoriatic skin lesion of at least 2 cm in diameter.
Croatian: Bolesnici su imali aktivan PsA (≥ 3 otečena zgloba i ≥ 3 bolna zgloba) unatoč prethodnom liječenju DMARD-ima te su imali jednu psorijatičnu kožnu leziju promjera najmanje 2 cm koja ih je kvalificirala za sudjelovanje u ispitivanju.
English: Live vaccines should not be given concurrently with abatacept or within 3 months of its discontinuation.
Croatian: Živa cjepiva ne smiju se davati istodobno s abataceptom niti unutar 3 mjeseca nakon prekida liječenja.
English: Their pJIA subtypes at disease onset were: oligoarticular (16%), polyarticular (64%; 20% of the total were rheumatoid factor positive), and systemic (20%).
Croatian: Na početku bolesti imali su sljedeće podtipove pJIA-e: oligoartikularni (16%), poliartikularni (64%, 20% od ukupnog broja bilo je pozitivno na reumatoidni faktor) i sustavni (20%).
English: Do not use the pre-filled syringe if the needle is damaged or bent.
Croatian: Nemojte upotrijebiti napunjenu štrcaljku ako je igla oštećena ili savijena.
English: Abatacept is not recommended for use in combination with TNF-inhibitors.
Croatian: Ne preporučuje se primjena abatacepta u kombinaciji s TNF-inhibitorima.
English: The effects of ORENCIA in pregnancy are not known, so do not use ORENCIA if you are pregnant unless your doctor specifically recommends it.
Croatian: Učinci lijeka ORENCIA u trudnoći nisu poznati te stoga nemojte primjenjivati lijek ORENCIA ako ste trudni, osim ako Vaš liječnik to izričito ne preporuči.
English: Needle guard (extended over needle)
Croatian: Štitnik za iglu (ispružen preko igle)
English: After proper training in subcutaneous injection technique, a patient may self-inject with ORENCIA if a physician/healthcare professional determines that it is appropriate.
Croatian: Nakon odgovarajuće obuke za primjenu supkutane tehnike injiciranja, bolesnik si može sam davati injekcije lijeka ORENCIA ako liječnik/zdravstveni radnik odluči da je to primjereno.
English: Population pharmacokinetic analysis of abatacept serum concentration data from patients with pJIA 6 to 17 years of age following administration of intravenous abatacept 10 mg/kg revealed that the estimated clearance of abatacept, when normalised for baseline body weight, was higher in pJIA patients (0.4 mL/h/kg for a child weighing 40 kg) versus adult rheumatoid arthritis patients.
Croatian: Populacijska farmakokinetička analiza podataka o serumskim koncentracijama abatacepta u bolesnika s pJIA-om u dobi od 6 do 17 godina nakon intravenske primjene abatacepta u dozi od 10 mg/kg otkrila je da je procijenjeni klirens abatacepta, kada se normalizira za početnu tjelesnu težinu, bio veći u bolesnika s pJIA-om (0,4 ml/h/kg za dijete teško 40 kg) naspram odraslih bolesnika s reumatoidnim artritisom.
English: Abatacept is produced by recombinant DNA technology in Chinese hamster ovary cells.
Croatian: Abatacept se proizvodi tehnologijom rekombinantne DNK u stanicama jajnika kineskog hrčka.
English: Step 5: Inject Your Dose of ORENCIA
Croatian: KORAK 5: Injicirajte dozu lijeka ORENCIA
English: ORENCIA is used to treat psoriatic arthritis alone or in combination with methotrexate.
Croatian: ORENCIA se za liječenje psorijatičnog artritisa koristi sama ili u kombinaciji s metotreksatom.
English: Less than 60 kg
Croatian: Manje od 60 kg
English: The open label period of the study provided an assessment of the ability of abatacept to maintain efficacy for subjects originally randomised to abatacept and the efficacy response of those subjects who were switched to abatacept following treatment with infliximab.
Croatian: Otvorena faza ispitivanja omogućila je procjenu sposobnosti abatacepta da održi djelotvornost u ispitanika koji su početno bili randomizirani na abatacept kao i procjenu djelotvornosti u onih ispitanika koji su prebačeni na abatacept nakon liječenja infliksimabom.
English: Certain vaccinations may cause infections from the vaccine.
Croatian: Cijepljenje određenim cjepivima može izazvati infekcije.
English: Serious infections at least possibly related to treatment were reported in 1.5% of abatacept-treated patients and 1.1% of placebo-treated patients.
Croatian: Ozbiljne infekcije koje su bile barem moguće povezane s liječenjem prijavljene su u 1,5% bolesnika liječenih abataceptom i 1,1% bolesnika koji su primali placebo.
English: The dose of abatacept was 500 mg for patients weighing less than 60 kg, 750 mg for patients weighing 60 to 100 kg, and 1,000 mg for patients weighing greater than 100 kg.
Croatian: Doza abatacepta iznosila je 500 mg za bolesnike tjelesne težine manje od 60 kg, 750 mg za bolesnike tjelesne težine 60 do 100 kg, odnosno 1000 mg za bolesnike teže od 100 kg.
English: There were six overall discontinuations during this period, only one of which was due to an AE (the SAE of post-operative wound infection).
Croatian: Tijekom tog je razdoblja liječenje prekinulo ukupno šest bolesnika, ali samo jedan od njih zbog nuspojave (zbog infekcije rane nakon operacije, koja se smatrala ozbiljnom nuspojavom).
English: A single study was conducted to determine the effect of monotherapy use of abatacept on immunogenicity following subcutaneous administration without an intravenous load.
Croatian: Provedeno je samo jedno ispitivanje radi određivanja učinaka monoterapije abataceptom na imunogenost nakon supkutane primjene bez intravenske udarne doze.
English: Remove the needle from the skin and let go of the surrounding skin.
Croatian: Izvadite iglu iz kože i pustite kožni nabor.
English: Tell your doctor immediately if you notice any of the following: severe rash, hives or other signs of allergic reaction swollen face, hands or feet trouble breathing or swallowing fever, persistent cough, weight loss, listlessness
Croatian: Odmah obavijestite liječnika ako primijetite neki od sljedećih simptoma: težak osip, koprivnjaču ili druge znakove alergijske reakcije oticanje lica, šaka ili stopala otežano disanje ili gutanje vrućicu, uporan kašalj, gubitak tjelesne težine, bezvoljnost
English: After influenza vaccination, 73 of 119 abatacept-treated patients without protective antibody levels at baseline were able to mount an adequate immune response of at least a 4-fold increase in antibody titers to trivalent influenza vaccine.
Croatian: Nakon cijepljenja protiv gripe, 73 od 119 bolesnika liječenih abataceptom koji na početku ispitivanja nisu imali zaštitnu razinu protutijela, uspjelo je postići odgovarajući imuni odgovor od najmanje četverostrukog povećanja titra protutijela na trovalentno cjepivo protiv gripe.
English: One hundred and eighty-seven of 3,877 (4.8%) patients developed anti-abatacept antibodies while on treatment.
Croatian: Tijekom liječenja su se u 187 od 3877 (4,8%) bolesnika razvila antitijela na abatacept.
English: What ORENCIA looks like and contents of the pack ORENCIA solution for injection (injection) is a clear, colourless to pale yellow solution.
Croatian: Kako ORENCIA izgleda i sadržaj pakiranja ORENCIA otopina za injekciju (injekcija) je bistra, bezbojna do blijedožuta otopina.
English: The total content of the pre-filled syringe should be administered as a subcutaneous injection only.
Croatian: Cjelokupan sadržaj napunjene štrcaljke treba primijeniti isključivo supkutanom injekcijom.
English: ORENCIA powder for concentrate for solution for infusion has not been studied in children and adolescents under 6 years of age, therefore ORENCIA powder for concentrate for infusion is not recommended for use in this patient population.
Croatian: ORENCIA prašak za koncentrat za otopinu za infuziju nije ispitivan u djece mlađe od 6 godina te se stoga ne preporučuje primjena ORENCIA praška za koncentrat za otopinu za infuziju u ovoj populaciji bolesnika.
English: ORENCIA subcutaneous (SC) may be initiated with or without an intravenous (IV) loading dose.
Croatian: Liječenje lijekom ORENCIA za supkutanu (s.c.) primjenu može započeti intravenskom udarnom dozom ili bez nje.
English: ORENCIA solution for injection in pre-filled syringe is used in children and adolescents aged 2 to 17 years when a previous disease-modifying medicine has not worked well or is not suitable for them.
Croatian: ORENCIA otopina za injekciju u napunjenoj štrcaljki koristi se u djece i adolescenata u dobi od 2 do 17 godina kad prethodni lijek koji modificira tijek bolesti nije dobro djelovao ili kad takav lijek nije prikladan za te bolesnike.
English: In SC-III the safety profiles of the three treatment groups (abatacept + MTX, abatacept monotherapy, MTX group) were overall similar.
Croatian: Sveukupno su sigurnosni profili u ispitivanju SC-III bili slični u sve tri liječene skupine (abatacept + MTX, monoterapija abataceptom, skupina liječena samo MTX-om).
English: Abatacept is a fusion protein produced by recombinant DNA technology in Chinese hamster ovary cells.
Croatian: Abatacept je fuzijski protein proizveden tehnologijom rekombinantne DNK na stanicama jajnika kineskog hrčka.
English: Hypersensitivity was reported uncommonly.
Croatian: Preosjetljivost je prijavljena manje često.
English: The patients entered in the trial were a mean of 12.4 years of age with mean disease duration of 4.4 years.
Croatian: Prosječna dob bolesnika uključenih u ispitivanje iznosila je 12,4 godine, dok im je bolest trajala prosječno 4,4 godine.
English: The use of ORENCIA is not expected to affect the ability to drive or use machines.
Croatian: Ne očekuje se da bi ORENCIA mogla utjecati na sposobnost vožnje i rada sa strojevima.
English: In case of overdose, it is recommended that the patient be monitored for any signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted.
Croatian: U slučaju predoziranja preporučuje se nadzirati bolesnika kako bi se uočili eventualni znakovi ili simptomi nuspojava te započeti odgovarajuće simptomatsko liječenje.
English: Rare (may affect up to 1 in 1,000 people): tuberculosis inflammation of uterus, fallopian tubes and/or ovaries gastrointestinal infection cancer of white blood cells, lung cancer
Croatian: Rijetko (mogu se javiti u do 1 na 1000 osoba): tuberkuloza upala maternice, jajovoda i/ili jajnika infekcije probavnog sustava rak bijelih krvnih stanica, rak pluća
English: e DAS28-CRP Remission is defined as a DAS28-CRP score < 2.6
Croatian: e Remisija prema DAS28-CRP definirana je kao DAS28-CRP rezultat < 2,6.
English: Juvenile rats seemed to be more sensitive to lymphocytic inflammation of thyroid.
Croatian: Mladi su štakori, čini se, osjetljiviji na limfocitnu upalu štitnjače.
English: DO NOT use if it is cracked or broken.
Croatian: Nemojte je upotrijebiti ako je napukla ili slomljena.
English: The pJIA SC study included 46 patients in the 2 to 5 year age cohort and 173 patients in the 6 to 17 year age cohort.
Croatian: Ispitivanje pJIA SC uključivalo je kohortu s 46 bolesnika u dobi od 2 do 5 godina i kohortu sa 173 bolesnika u dobi od 6 do 17 godina.
English: Liver function test abnormal (including transaminases increased)
Croatian: Poremećaji jetre i žuči često abnormalni rezultati testova jetrene funkcije (uključujući povišene vrijednosti transaminaza)
English: It is important that you tell your baby's doctors and other health care professionals about your ORENCIA use during your pregnancy before the baby receives any vaccine (for more information see section on vaccination).
Croatian: Važno je da obavijestite liječnika i druge zdravstvene radnike koji skrbe o Vašem djetetu o tome da ste primali lijek ORENCIA tijekom trudnoće prije nego što Vaše dijete primi bilo koje cjepivo (za više informacija pogledajte odlomak o cijepljenju).
English: Women of childbearing potential have to use effective contraception during treatment and up to 14 weeks after the last dose of abatacept.
Croatian: Žene reproduktivne dobi moraju koristiti djelotvornu kontracepciju tijekom liječenja i do 14 tjedana nakon posljednje doze abatacepta.
English: This medicine contains 34.5 mg sodium (main component of cooking/table salt) per maximum dose of 4 vials (8.625 mg sodium per vial).
Croatian: Ovaj lijek sadrži 34,5 mg natrija (glavnog sastojka kuhinjske soli) po najvećoj dozi od 4 bočice (8,625 mg natrija po bočici).
English: *(e.g. pruritus, throat tightness, dyspnea)
Croatian: * (npr. svrbež, stezanje grla, dispneja)
English: The reduction from baseline in mean DAS28 score at day 365 (-3.06) was maintained through day 729 (-3.34) in those patients who continued with abatacept.
Croatian: Smanjenje prosječnog DAS28 rezultata 365. dana u odnosu na početne vrijednosti (-3,06) održalo se do 729. dana (-3,34) u onih bolesnika koji su nastavili primati abatacept.
English: Table 8:
Croatian: Tablica 8:
English: This means that before ORENCIA is given to you, it is first dissolved in water for injections, then further diluted with sodium chloride 9 mg/mL (0.9%) solution for injection.
Croatian: To znači da se prije nego što primite lijek ORENCIA, on najprije mora otopiti u vodi za injekcije, a zatim dodatno razrijediti otopinom natrijevog klorida za injekciju od 9 mg/ml (0,9%).
English: Study SC-I compared the safety of abatacept including injection site reactions following subcutaneous or intravenous administration.
Croatian: U ispitivanju SC-I uspoređivala se sigurnost primjene abatacepta, uključujući reakcije na mjestu injekcije nakon supkutane odnosno intravenske primjene.
English: The safety and efficacy of intravenous ORENCIA in children below 6 years of age have not been studied and therefore, intravenous ORENCIA is not recommended for use in children under six years old.
Croatian: Sigurnost i djelotvornost lijeka ORENCIA za intravensku primjenu u djece mlađe od 6 godina nisu ispitane te se stoga intravenska primjena lijeka ORENCIA ne preporučuje kod djece mlađe od 6 godina.
English: Further improvement was observed at 12 months with abatacept.
Croatian: Kod primjene abatacepta zabilježeno je daljnje poboljšanje nakon 12 mjeseci.
English: c Patients who had less than 20% improvement in tender or swollen joint counts at Week 16 met escape criteria and were considered non-responders.
Croatian: c Bolesnici kojima se broj bolnih i otečenih zglobova poboljšao za manje od 20% do 16. tjedna ispunjavali su kriterije za prijevremeni prelazak na abatacept i smatrali su se bolesnicima bez odgovora.
English: Don't touch the plunger while you remove the needle cover.
Croatian: Nemojte dodirivati klip dok skidate poklopac s igle.
English: It is normal to see an air bubble, and there is no reason to remove it. All contents of the syringe should be injected.
Croatian: Normalno je da vidite mjehurić zraka i nema potrebe da ga uklanjate.
English: During the 12-month treatment period, adverse reactions were reported in 44.5% (53/119), 41.4% (48/116), and 44.0% (51/116) and serious adverse reactions were reported in 2.5% (3/119), 2.6% (3/116) and 0.9% (1/116) of patients treated in the three treatment groups, respectively.
Croatian: Tijekom 12-mjesečnog razdoblja liječenja, nuspojave su prijavljene u 44,5% (53/119), 41,4% (48/116) odnosno 44,0% (51/116) bolesnika, dok su ozbiljne nuspojave prijavljene u 2,5% (3/119), 2,6% (3/116) odnosno 0,9% (1/116) bolesnika liječenih u navedene tri skupine.
English: Of the 219 patients with pJIA treated with subcutaneous abatacept during the first 4-month abatacept treatment, the frequency of local injection reactions was 4.6% (10/219); injection site pain and injection site erythema were the most frequently reported local injection reactions.
Croatian: Od 219 bolesnika s pJIA-om koji su tijekom prva 4 mjeseca liječenja primali supkutanu formulaciju abatacepta učestalost lokalnih reakcija na injekciju iznosila je 4,6% (10/219), a najčešće prijavljene lokalne reakcije na injekciju bile su bol na mjestu injiciranja i eritem na mjestu injiciranja.
English: It is not known whether ORENCIA passes into human milk.
Croatian: Nije poznato izlučuje li se ORENCIA u majčino mlijeko.
English: At 12 months 61% (148/242) of the patients treated with abatacept plus methotrexate and 53% (128/242) of the patients treated with methotrexate plus placebo had no progression (TSS ≤ 0).
Croatian: Nakon 12 mjeseci, u 61% (148/242) bolesnika liječenih abataceptom i metotreksatom te u 53% (128/242) bolesnika koji su primali metotreksat i placebo nije došlo do progresije (TSS ≤ 0).
English: A study in the subcutaneous program was conducted to investigate the effect of withdrawal (three months) and restart of abatacept subcutaneous treatment on immunogenicity.
Croatian: U sklopu programa ispitivanja supkutane primjene lijeka provedeno je ispitivanje učinaka prekida primjene (na 3 mjeseca) te ponovnog uvođenja supkutanog liječenja abataceptom na imunogenost.
English: There is no relevant use of ORENCIA in children under two years old.
Croatian: Nema relevatne primjene lijeka ORENCIA u djece mlađe od dvije godine.
English: Hypertension, blood pressure increased Uncommon Hypotension, hot flush, flushing, vasculitis, blood pressure decreased
Croatian: Krvožilni poremećaji često hipertenzija, povišen krvni tlak manje često hipotenzija, navala vrućine, navale crvenila, vaskulitis, snižen krvni tlak
English: Respiratory disorders occurred more frequently in abatacept-treated patients than in placebo-treated patients (10.8% vs. 5.9%, respectively); these included COPD exacerbation, and dyspnea.
Croatian: Poremećaji respiratornog trakta razvijali su se češće u bolesnika liječenih abataceptom nego u bolesnika koji su primali placebo (10,8% naspram 5,9%), a obuhvaćali su pogoršanje KOPB-a i dispneju.
English: Note: It is normal to see a drop of fluid leaving the needle.
Croatian: Napomena: Normalno je da iz igle izađe kapljica tekućine.
English: Under aseptic conditions, reconstitute each vial with 10 mL of water for injections, using the silicone-free disposable syringe provided with each vial (see section 6.2) and an 18-21 gauge needle.
Croatian: U aseptičkim uvjetima rekonstituirajte svaku bočicu s 10 ml vode za injekcije, koristeći nesilikonsku štrcaljku za jednokratnu uporabu priloženu uz svaku bočicu (vidjeti dio 6.2) i iglu veličine 18-21 G.
English: Doses up to 50 mg/kg have been administered without apparent toxic effect.
Croatian: Primjena doza do 50 mg/kg nije izazvala vidljive toksične učinke.
English: Do not give the injection in any areas with scars or stretch marks.
Croatian: Nemojte injicirati lijek u područja s ožiljcima i strijama.
English: The safety and efficacy of subcutaneous abatacept were assessed in a single-arm, open-label study designed with a primary endpoint of steady-state trough concentration (cmin) at 4 months (short-term period) in the 6 to 17 year age cohort.
Croatian: Sigurnost i djelotvornost supkutane formulacije abatacepta ocjenjivale su se u otvorenom ispitivanju s jednom skupinom u kojem je primarna mjera ishoda bila najniža koncentracija (Cmin) u stanju dinamičke ravnoteže nakon 4 mjeseca (kratkoročno razdoblje) u kohorti bolesnika u dobi od 6 do 17 godina starosti.
English: How often ORENCIA is given to you
Croatian: Koliko često ćete primati lijek ORENCIA
English: The effects of ORENCIA in pregnancy are not known, so you should not be given ORENCIA if you are pregnant unless your doctor specifically recommends it.
Croatian: Učinci lijeka ORENCIA u trudnoći nisu poznati te stoga ne smijete primati lijek ORENCIA ako ste trudni, osim ako Vaš liječnik to izričito ne preporuči.
English: In study SC-I, abatacept administered subcutaneously (SC) was non-inferior relative to intravenous (IV) infusions of abatacept with respect to ACR 20 responses up to 6 months of treatment.
Croatian: U ispitivanju SC-I abatacept primijenjen supkutano (s.c.) nije bio inferioran u odnosu na intravenske (i.v.) infuzije abatacepta u pogledu odgovora ACR20 u razdoblju do 6 mjeseci liječenja.
English: In the substudy of study VI, patients who had achieved remission at 2 years (DAS 28 ESR < 2.6) and after at least 1 year of treatment with abatacept in study VI were eligible to enter a substudy.
Croatian: Bolesnici koji su nakon 2 godine postigli remisiju (DAS28 ESR [sedimentacija eritrocita] < 2,6) i najmanje godinu dana su bili liječeni abataceptom u ispitivanju VI, mogli su se uključiti u podispitivanje u sklopu ispitivanja VI.
English: The other ingredients are maltose, sodium dihydrogen phosphate monohydrate and sodium chloride (see section 2 "ORENCIA contains sodium").
Croatian: Drugi sastojci su: maltoza, natrijev dihidrogenfosfat hidrat i natrijev klorid (vidjeti dio 2. "ORENCIA sadrži natrij").
English: The COPD patients treated with abatacept developed adverse reactions more frequently than those treated with placebo (51.4% vs. 47.1%, respectively).
Croatian: U bolesnika s KOPB-om liječenih abataceptom nuspojave su se javljale češće nego u onih koji su primali placebo (51,4% naspram 47,1%).
English: It is recommended that patients with polyarticular juvenile idiopathic arthritis, if possible, be brought up to date with all immunisations in agreement with current immunisation guidelines prior to starting ORENCIA therapy.
Croatian: Preporučuje se da bolesnici s poliartikularnim juvenilnim idiopatskim artritisom po mogućnosti obave sva cijepljenja u skladu s važećim programom cijepljenja prije početka liječenja lijekom ORENCIA.
English: Study SC-I was a randomised, double-blind, double-dummy noninferiority study administered to patients stratified by body weight (< 60 kg, 60 to 100 kg, > 100 kg) that compared the efficacy and safety of abatacept administered subcutaneously and intravenously in subjects with rheumatoid arthritis (RA), receiving background methotrexate (MTX), and experiencing an inadequate response to MTX (MTX-IR).
Croatian: Ispitivanje SC-I bilo je randomizirano, dvostruko slijepo, dvostruko maskirano ispitivanje neinferiornosti u bolesnika stratificiranih prema tjelesnoj težini (< 60 kg, 60 do 100 kg, > 100 kg), u kojemu se uspoređivala djelotvornost i sigurnost abatacepta primijenjenog supkutano i intravenski u ispitanika s reumatoidnim artritisom koji su primali osnovnu terapiju metotreksatom (MTX) na koju nisu dovoljno dobro odgovorili (engl. inadequate response to MTX, MTX-IR).
English: In study II, the baseline median TSS was 31.7 in abatacept-treated patients and 33.4 in placebo-treated patients.
Croatian: U ispitivanju II je početni medijan TSS-a bio 31,7 u bolesnika liječenih abataceptom, odnosno 33,4 u bolesnika koji su primali placebo.
English: Remission rates at end of drug treatment and drug withdrawal phases in study SC-III
Croatian: Stope remisije na kraju razdoblja liječenja i razdoblja bez liječenja u ispitivanju SC-III
English: When the reconstituted solution is diluted immediately, the chemical and physical in-use stability of the diluted infusion solution has been demonstrated for 24 hours at 2°C - 8°C.
Croatian: Kada se rekonstituirana otopina odmah razrijedi, dokazana kemijska i fizikalna stabilnost razrijeđene otopine za infuziju je 24 sata na temperaturi od 2°C - 8°C.
English: Injection sites should be rotated and injections should never be given into areas where the skin is tender, bruised, red, or hard.
Croatian: Treba mijenjati mjesta injiciranja, a injekcija se nikada ne smije davati u područja na kojima je koža osjetljiva, gdje su prisutne modrice, crvenilo ili otvrdnuća.
English: Improvement in HAQ-DI scores was maintained or improved for up to 1 year with continuing abatacept treatment in both PsA-I and PsA-II studies.
Croatian: Poboljšanja HAQ-DI indeksa održala su se ili poboljšavala do godinu dana uz nastavak liječenja abataceptom i u ispitivanju
English: Pinch the skin
Croatian: Nabor kože