FrancophonIA/ELRC3.0 huggingface dataset:
English: Alternative corticosteroids which are less dependent on CYP3A metabolism e.g. beclomethasone for intranasal or inhalational use should be considered, particularly for long term use.
Slovenian: O uporabi kortikosteroidov, ki so manj odvisni od presnove s CYP3A, npr. intranazalniali inhalacijski beklometazon, pa je treba razmisliti, predvsem pri dolgotrajnem zdravljenju.
English: What you need to know before you take Darunavir Krka d.d.
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Darunavir Krka d.d.
English: When used in combination with darunavir co-administered with low dose ritonavir, dose adjustment of indinavir from 800 mg twice daily to 600 mg twice daily may be warranted in case of intolerance.
Slovenian: Pri uporabi v kombinaciji z darunavirjem z majhnim odmerkom ritonavirja bo v primeru intolerance morda treba zmanjšatiodmerek indinavirja z 800 mg dvakrat na dan na 600 mg dvakrat na dan.
English: Viruses isolated from patients on darunavir/ritonavir 600/100 mg twice daily experiencing virologic failure by rebound that were susceptible to tipranavir at baseline remained susceptible to tipranavir after treatment in the vast majority of cases.
Slovenian: Virusi, izolirani pri bolnikih, ki so prejemali darunavir/ritonavir 600/100 mg dvakrat na dan, pri katerih je prišlo do virološke odpovedi in so bili na začetku preskušanj občutljivi za tipranavir, so v veliki večini primerov ostali občutljivi za tipranavir tudi po zdravljenju.
English: Pregnant or breast-feeding mothers should not take Darunavir Krka d.d.
Slovenian: Noseče ali doječe matere ne smejo jemati zdravila Darunavir Krka d.d.
English: These patients received darunavir 800 mg once daily in combination with cobicistat 150 mg once daily with an investigator selected background regimen consisting of 2 active NRTIs.
Slovenian: Ti bolniki so prejemali 800 mg darunavirja enkrat na dan skupaj s 150 mg kobicistata enkrat na dan in z optimiziranim osnovnim režimom zdravljenja (OBR) z dvema aktivnima NRTI po izboru raziskovalca.
English: every day and always in combination with 150 milligram of cobicistat or 100 milligram of ritonavir and with food.
Slovenian: morate jemati vsak dan in vedno skupaj s 150 mg kobicistata ali 100 mg ritonavirja in s hrano.
English: Bosentan is expected to decrease plasma concentrations of darunavir and/or its pharmacoenhancer.
Slovenian: Bosentan pričakovano zniža plazemske koncentracije darunavirja in/ali njegovih farmakokinetičnihojačevalcev.
English: • For the treatment of HIV-1 infection in paediatric patients from the age of 3 years and at least
Slovenian: - za zdravljenje okužbe z virusom HIV-1 pri pediatričnih bolnikih, starih najmanj 3 leta in s telesno maso najmanj 15 kg.
English: Number of subjects with virologic failure a and phenotype data that show resistance to PIs at endpoint c, n/N
Slovenian: Število virološko neuspešnih bolnikov a in podatki o fenotipu, ki kažejo odpornost proti PI ob zaključku zdravljenja c, n/N
English: See the Summary of Product Characteristics for Darunavir Krka d.d.
Slovenian: Glejte Povzetek glavnih značilnosti zdravila Darunavir Krka d.d.
English: Several of the interaction studies (indicated by # in the table below) have been performed at lower than recommended doses of darunavir or with a different dosing regimen (see section 4.2 Posology).
Slovenian: Številne študije medsebojnega delovanja z drugimi zdravili (označene z # v spodnji preglednici) so bile opravljene pri odmerkih darunavirja, ki so bili nižji od priporočenega, ali z drugačnimi režimi odmerjanja (glejte poglavje 4.2 Odmerjanje).
English: The doctor will inform you on how many Darunavir Krka d.d.
Slovenian: Zdravnik vam bo povedal, koliko tablet zdravila Darunavir Krka d.d.
English: Atorvastatin 10 mg once daily atorvastatin AUC ↑ 3-4 fold atorvastatin Cmin ↑ ≈5.5-10 fold atorvastatin Cmax ↑ ≈2 fold darunavir/ritonavir
Slovenian: atorvastatin 10 mg enkrat na dan atorvastatin AUC ↑ 3- do 4-krat atorvastatin Cmin ↑ ≈5,5- do 10krat atorvastatin Cmax ↑ ≈2-krat #darunavir/ritonavir
English: Adverse reactions observed with darunavir/ritonavir in clinical trials and post-marketing
Slovenian: Neželeni učinki kombinacije darunavir/ritonavir, opaženi v kliničnih študijah in v obdobju trženja zdravila
English: cobicistat should not be used in combination with another antiretroviral agent that requires pharmacoenhancement by means of co-administration with an inhibitor of CYP3A4 (see section 4.5).
Slovenian: Kombinacija darunavirja s kobicistatom se ne sme uporabljati skupaj s protiretrovirusnimi učinkovinami, ki zahtevajo farmakokinetično okrepitev s sočasnim jemanjem zaviralca CYP3A4 (glejte poglavje 4.5).
English: must be taken in combination with a low dose of ritonavir and other anti-HIV medicines.
Slovenian: je treba jemati skupaj z majhnim odmerkom ritonavirja in z drugimi zdravili proti okužbi s HIV.
English: with darunavir/cobicistat 800/150 mg
Slovenian: skupaj s kombinacijo darunavir/kobicistat 800/150 mg
English: At week 48, the virologic response, defined as the percentage of patients with confirmed plasma viral load < 50 HIV-1 RNA copies/ml, was evaluated in 16 paediatric patients 15 kg to < 20 kg and 5 paediatric patients 10 kg to < 15 kg receiving darunavir/ritonavir in combination with other antiretroviral agents (see section 4.2 for dosage recommendations per body weight).
Slovenian: Po 48 tednih so potrdili virološki odziv (določen kot odstotek bolnikov s potrjeno plazemsko koncentracijo HIV-1 RNK < 50 kopij/ml) pri 16 pediatričnih bolnikih s telesno maso 15 kg do < 20 kg in pri 5 pediatričnih bolnikih s telesno maso 10 kg do < 15 kg pri režimu zdravljenja z zdraviloma darunavir/ritonavir v kombinaciji drugimi protiretrovirusnimi zdravili (za priporočila za odmerjanje glede na telesno maso glejte poglavje 4.2).
English: Concomitant use of other PDE-5 inhibitors for the treatment of erectile dysfunction with boosted darunavir should be done with caution.
Slovenian: Pri sočasni uporabi zaviralcev PDE5 (za zdravljenje motenj erekcije) z okrepljenim darunavirjem je potrebna previdnost.
English: may still develop infections or other illnesses associated with HIV infection.
Slovenian: Pri osebah, ki jemljejo zdravilo Darunavir Krka d.d., se lahko še vedno pojavijo okužbe ali druge bolezni, ki so povezane z okužbo s HIV.
English: These may include yellowing of your skin or whites of your eyes, dark (tea coloured) urine, pale coloured stools (bowel movements), nausea, vomiting, loss of appetite, or pain, aching, or pain and discomfort on your right side below your ribs.
Slovenian: Ti lahko vključujejo rumenenje kože ali očesnih beločnic, temno obarvan (v barvi čaja) urin, svetlo blato (odvajanje blata), slabost, bruhanje, izgubo apetita ali bolečino oziroma bolečino in nelagodjena desni strani telesa, pod rebri.
English: Darunavir co-administered with low dose ritonavir must not be combined with medicinal products that are highly dependent on CYP3A for clearance and for which increased systemic exposure is associated with serious and/or life-threatening events (narrow therapeutic index) (see section 4.3).
Slovenian: Darunavir, skupaj z majhnim odmerkom ritonavirja ne smete uporabljati sočasno z zdravili, katerih očistek je močno odvisen od CYP3A in pri katerih je zvečana sistemska izpostavljenost povezana z resnimi in/ali življenjsko nevarnimi neželenimi učinki (majhna terapevtska širina) (glejte poglavje 4.3).
English: with cobicistat or ritonavir has not been tested with all PIs (protease inhibitors) and must not be used with other HIV PIs.
Slovenian: s kobicistatom ali ritonavirjem ni bilo preskušano v kombinaciji z vsemi zaviralci proteaz in se ne sme uporabljati skupaj z drugimi zaviralci proteaz HIV.
English: is and what it is used for What you need to know before you take Darunavir Krka d.d.
Slovenian: in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Darunavir Krka d.d.
English: HIV ANTIRETROVIRALS Integrase strand transfer inhibitors Dolutegravir dolutegravir AUC ↓ 22% dolutegravir C24h ↓38% dolutegravir Cmax ↓ 11% darunavir ↔* * Using cross-study comparisons to historical pharmacokinetic data
Slovenian: PROTIRETROVIRUSNA ZDRAVILA PROTI HIV Zaviralci prenosa virusnega genoma s pomočjo encima integraze dolutegravir dolutegravir AUC ↓ 22 % dolutegravir C24h ↓ 38 % dolutegravir Cmax ↓ 11 % darunavir ↔* * medštudijska primerjava s predhodnimi farmakokinetičnimi podatki
English: #, a comparable systemic exposure to sildenafil was observed for a single intake of 100 mg sildenafil alone and a single intake of 25 mg sildenafil co-administered with darunavir and low dose ritonavir.
Slovenian: V študiji medsebojnih delovanj# je bila sistemska izpostavljenost sildenafilu po zaužitju enkratnega odmerka 100 mg samega sildenafila in enkratnega odmerka 25 mg sildenafila skupaj z darunavirjem in majhnim odmerkom ritonavirja primerljiva.
English: Ciclosporin, everolimus, tacrolimus, sirolimus (for dampening down your immune system) as the therapeutic effect or side effects of these medicines might be increased.
Slovenian: - klaritromicin(antibiotik) - ciklosporin, everolimus, takrolimus, sirolimus (za zaviranje aktivnostiimunskega sistema), ker se lahko zvečajo terapevtski ali neželeni učinki teh zdravil.
English: Virogic failures were defined as: never suppressed: confirmed HIV-1 RNA < 1 log10 reduction from baseline and ≥ 50 copies/ml at the week-8; rebound: HIV-1 RNA < 50 copies/ml followed by confirmed HIV-1 RNA to ≥ 400 copies/ml or confirmed > 1 log10 HIV-1 RNA increase from the nadir; discontinuations with HIV-1 RNA ≥ 400 copies/ml at last visit IAS-USA lists In GS-US216-130 baseline phenotype was not available
Slovenian: PI HIV darunavir amprenavir atazanavir indinavir lopinavir sakvuinavir tipranavir virološki neuspeh zdravljenja je bil opredeljen kot: brez supresije: zmanjšanje koncentracije HIV-1 RNK za < 1 log10 glede na začetno vrednost in ≥ 50 kopij/ml po 8 tednih zdravljenja, potrjeno pri naslednjem obisku; povratni učinek: koncentracija HIV-1 RNK< 50 kopij/ml s kasnejšim potrjenim zvišanjem koncentracije HIV-1 RNK na ≥ 400 kopij/ml ali s potrjenim zvišanjem koncentracije HIV-1 RNK za > 1 log10 od najnižje vrednosti; prekinitve s koncentracijo HIV-1 RNK ≥ 400 kopij/ml pri zadnjem obisku po seznamih IAS-USA (International AIDS Society-USA) v študiji GS-US-216-130 ni bilo na voljo podatkov o začetnem stanju fenotipa
English: HIV-1 infected patients who were eligible for this trial had a screening genotype showing no darunavir RAMs and plasma HIV-1 RNA ≥ 1,000 copies/ml.
Slovenian: Z virusom HIV-1 okuženi bolniki, ki so bili primerni za to študijo, so imeli v izbirnem (screening) postopku genotip brez mutacij, povezanih z odpornostjo proti darunavirju, in plazemsko koncentracijo HIV-1 RNK ≥ 1.000 kopij/ml.
English: Your doctor will advise you how to deal with your symptoms or whether Darunavir Krka d.d.
Slovenian: Zdravnik vam bo povedal, kako glede na vaše simptome ravnati in ali je treba prekiniti zdravljenje z zdravilom Darunavir Krka d.d..
English: (induction of CYP450 enzymes) Concentrations of voriconazole may increase or decrease when co-administered with darunavir co-administered with cobicistat.
Slovenian: (indukcija encimov CYP450) Sočasna uporaba darunavirja in kobicistata lahko zviša ali zniža koncentracije vorikonazola.
English: Nevirapine 200 mg twice daily nevirapine AUC ↑ 27% nevirapine Cmin ↑ 47% nevirapine Cmax ↑ 18% darunavir: concentrations were consistent with historical data (↑ nevirapine from CYP3A inhibition)
Slovenian: nevirapin 200 mg dvakrat na dan nevirapin AUC ↑ 27 % nevirapin Cmin ↑ 47 % nevirapin Cmax ↑ 18 % # koncentracije darunavirja so bile skladne s starejšimi podatki (↑ nevirapina zaradi zaviranja CYP3A)
English: Take Darunavir Krkad.d.with food.
Slovenian: - Zdravilo Darunavir Krka d.d.vzemite s hrano.
English: If parenteral midazolam is coadministered with boosted darunavir, it should be done in an intensive care unit (ICU) or similar setting, which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Slovenian: Če je treba okrepljen darunavir uporabljati sočasno s parenteralno obliko midazolama, ju je treba odmerjati na oddelku intenzivne terapije ali v podobni enoti, kar zagotavlja skrbno spremljanje bolnika in ustrezno zdravljenje v primeru depresije dihanja in/ali dolgotrajne sedacije.
English: Concomitant use of other PDE-5 inhibitors for the treatment of erectile dysfunction with darunavir coadministered with low dose ritonavir should be done with caution.
Slovenian: Pri sočasni uporabi zaviralcev PDE-5 (za zdravljenje motenj erekcije) z darunavirjem z majhnim odmerkom ritonavirja je potrebna previdnost.
English: Caution should be used in pregnantwomen with concomitant medications which may further decrease darunavir exposure (see sections 4.5 and 5.2).
Slovenian: Pri nosečnicah, ki sočasno jemljejo zdravila, ki lahko dodatno zmanjšajo izpostavljenost darunavirju, je potrebna previdnost (glejte poglavji 4.5 in 5.2).
English: 400 mg and 800 mg tablets may be used to provide suitable dose regimens for the treatment of HIV-1 infection in adult and paediatric patients from the age of 3 years and at least 40 kg body weight who are: antiretroviral therapy (ART)-naïve (see section 4.2).
Slovenian: 400 mg in 800 mg tablete se lahko uporabljajo za zagotavljanje ustreznega odmerjanja za zdravljenje okužbe z virusom HIV-1 pri odraslih in pediatričnih bolnikih, starih 3 leta in več in s telesno maso najmanj 40 kg:
English: The dosage of other medicines might need to be changed since either their own or Darunavir Krka d.d.
Slovenian: Lahko bo potrebna tudi sprememba odmerjanja drugih zdravil, zaradi vpliva kombinacije na terapevtske ali neželene učinke le-teh ali zdravila Darunavir Krka d.d..
English: based on published data with darunavir/ritonavir rosuvastatin AUC ↑ 93% rosuvastatin Cmax ↑ 277% rosuvastatin Cmin ND
Slovenian: ║ na osnovi objavljenih podatkov s kombinacijo darunavir/ritonavir rosuvastatin AUC ↑ 93%
English: (CYP3A and OATP1B inhibition)
Slovenian: (zaviranjeCYP3Ain OATP1B)
English: Darunavir/ritonavir N=12
Slovenian: Izidi po 48. tednu darunavir/ritonavir n = 12
English: - The other ingredients are cellulose, microcrystalline; crospovidone, hydroxypropylcellulose; silica, colloidal anhydrous; silicified microcrystalline cellulose (cellulose, microcrystalline; silica, colloidal anhydrous) and magnesium stearate (E470b) in the tablet core and poly(vinyl alcohol), macrogol, titanium dioxide (E171), talc (E553b), yellow iron oxide (E172) and red iron oxide (E172) in film coating.
Slovenian: - Druge sestavine zdravila so mikrokristalna celuloza, krospovidon, hidroksipropilceluloza, brezvodni koloidni silicijev dioksid, silicizirana mikrokristalna celuloza (mikrokristalna celuloza, brezvodni koloidni silicijev dioksid) in magnezijev stearat (E470b) v jedru tablete ter polivinilalkohol, makrogol, titanov dioksid (E171), smukec (E553b), rumeni železov oksid (E172) in rdeči železov oksid (E172) v filmski oblogi.
English: Darunavir/ritonavir N=80
Slovenian: Izidi po 48. tednu darunavir/ritonavir n = 80
English: 400 mg film-coated tablets Darunavir Krka d.d.
Slovenian: 400 mg filmsko obložene tablete Darunavir Krka d.d.
English: These are mentioned above under the heading ‘Do not combine Darunavir Krka d.d.
Slovenian: Navedena so zgoraj pod naslovom "Zdravila Darunavir Krka d.d.
English: Tenofovir disoproxil 245 mg once daily tenofovir AUC ↑ 22% tenofovir Cmin ↑ 37% tenofovir Cmax ↑ 24% darunavir AUC ↑ 21% darunavir Cmin ↑ 24% darunavir Cmax ↑ 16% (↑ tenofovir from effect on MDR-1 transport in the renal tubules)
Slovenian: dizoproksiltenofovirat 245 mg enkrat na dan tenofovir AUC ↑ 22 % tenofovir Cmin ↑ 37 % tenofovir Cmax ↑ 24 % #darunavir AUC ↑ 21 % #darunavir Cmin ↑ 24 % #darunavir Cmax ↑ 16 % (↑ tenofovirja zaradi učinka na MDR-1 transport v ledvičnih tubulih)
English: Concentrations of these medicinal products may be increased when coadministered with darunavir with low dose ritonavir resulting in the potential for increased adverse events usually associated with these agents.
Slovenian: Koncentracije teh zdravil se lahko pri sočasnem dajanju z darunavirjem skupaj z majhnim odmerkom ritonavirja zvišajo, kar lahko zveča možnost za neželene učinke, ki se običajno pojavljajo pri uporabi teh zdravil.
English: Based on theoretical considerations boosted darunavir is expected to increase the exposure of lomitapide when coadministered.
Slovenian: Glede na teoretična izhodišča je mogoče pričakovati, da okrepljen darunavir, kadar je sočasno uporabljeno z lomitapidom zviša izpostavljenost lomitapidu.
English: The evidence of efficacy of darunavir/ritonavir 800/100 mg once daily is based on the analyses of 192 week data from the randomised, controlled, open-label Phase III trial ARTEMIS in antiretroviral treatment-naïve HIV-1 infected patients comparing darunavir/ritonavir 800/100 mg once daily with lopinavir/ritonavir 800/200 mg per day (given as a twice-daily or as a once-daily regimen).
Slovenian: Učinkovitost 800 mg darunavirja enkrat na dan skupaj s 100 mg ritonavirja enkrat na dan pri bolnikih, ki še nimajo izkušenj z ART Dokazi o učinkovitosti zdravil darunavir/ritonavir 800/100 mg enkrat na dan temeljijo na analizi podatkov po 192 tednih zdravljenja v randomiziranem, nadzorovanem, odprtem kliničnem preskušanju faze III (ARTEMIS), pri bolnikih, okuženih s HIV-1, ki še niso prejemali protiretrovirusnega zdravljenja, v katerem so primerjali kombinaciji darunavir/ritonavir 800/100 mg enkrat na dan in lopinavir/ritonavir 800/200 mg na dan (ki so ga dajali z režimom dvakrat na dan ali enkrat na dan).
English: Check with your doctor, pharmacist or nurse if you are not sure.
Slovenian: se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
English: 21 ART-experienced HIV-1 infected paediatric patients aged from 3 to < 6 years and weighing 10 kg to < 20 kg (16 participants from 15 kg to < 20 kg) who received darunavir oral suspension with low dose ritonavir twice daily in combination with other antiretroviral agents.
Slovenian: - 21 sHIV-1 okuženih pediatričnih bolnikov, starih 3 do< 6 let in s telesno maso 10 kg do < 20 kg (16 preiskovancev s telesno maso 15 kg do < 20 kg), z izkušnjami z ART, ki so prejemali peroralno suspenzijo darunavirja skupaj z majhnim odmerkom ritonavirja dvakrat na dan in drugimi protiretrovirusnimi zdravili.
English: Number of subjects with virologic failure a and genotype data that develop mutations b at endpoint, n/N
Slovenian: Število virološko neuspešnih bolnikov a in podatki o genotipu, ki omogoča razvoj mutacij b ob zaključku zdravljenja, n/N
English: If you forget to take Darunavir Krka d.d.
Slovenian: Če ste pozabili vzeti zdravilo Darunavir Krka d.d.
English: The interaction profile of darunavir depends on whether ritonavir or cobicistat is used as pharmacokinetic enhancer.
Slovenian: Profil medsebojnega delovanja darunavirja je odvisen od tega, ali je farmakokinetični ojačevalec ritonavir ali kobicistat.
English: Darunavir/ritonavirshould be used during pregnancy only if the potential benefit justifies the potential risk.
Slovenian: Kombinacijo zdravil darunavir/ritonavir se lahko uporablja med nosečnostjo le, če možna korist pretehta morebitno tveganje.
English: Titanium dioxide (E171)
Slovenian: polivinilalkohol makrogol titanov dioksid (E171) smukec (E553b)
English: Always take with cobicistat or ritonavir and food.
Slovenian: Zdravilo vedno jemljite s kobicistatom ali z ritonavirjem in s hrano.
English: with any of the following medicines:'
Slovenian: ne smete kombinirati z nobenim od naslednjih zdravil".
English: 800 mg film-coated tablets are available in bottles containing 30 film-coated tablets (1 bottle of 30 film-coated tablets) and 90 film-coated tablets (3 bottles of 30 film-coated tablets) in a box.
Slovenian: 800 mg filmsko obložene tablete so na voljo v plastenkah po 30 filmsko obloženih tablet (1 plastenka po 30 filmsko obloženih tablet) in 90 filmsko obloženih tablet (3 plastenke po 30 filmsko obloženih tablet).
English: Of the 44 patients taking ritonavir oral solution, 27 switched to the 100 mg capsule formulation and exceeded the weight based ritonavir dose without changes in observed safety.
Slovenian: Od 44 bolnikov, ki so jemali peroralno raztopino ritonavirja, jih je 27 prešlo na jemanje 100 mg kapsul.
English: Lopinavir/ ritonavir 800/200 mg per day N=346
Slovenian: lopinavir/ ritonavir 800/200 m na dan n = 346
English: Take your other HIV medicines used in combination with Darunavir Krka d.d.
Slovenian: - Po navodilih zdravnika vzemite tudi ostala zdravila proti HIV, ki jih uporabljate v kombinaciji z zdraviloma Darunavir Krka d.d.
English: based on published data with darunavir/ritonavir
Slovenian: ║ na osnovi objavljenih podatkov s kombinacijo darunavir/ritonavir
English: 600 mg tablets (see section
Slovenian: 600 mg tablete (glejte poglavje 4.5).
English: Outcomes darunavir/ritonavir
Slovenian: s kombinacijo darunavir/ritonavir
English: If efavirenz is to be used in combination with darunavir, the darunavir/ritonavir 600/100 mg twice daily regimen should be used (see section 4.5).
Slovenian: Če je treba kombinirati efavirenz in darunavir, je treba uporabljati režim darunavir/ritonavir 600/100 mg dvakrat na dan (glejte poglavje 4.5).
English: Concomitant use of salmeterol and boosted darunavir may increase plasma concentrations of salmeterol.
Slovenian: Pri sočasni uporabi salmeterola in okrepljenega darunavirja lahko pride do zvišanja plazemskih koncentracij salmeterola.
English: looks like and contents of the pack Film-coated tablets (tablets) are orangish brown, oval, biconvex, engraved with a mark S2 on one side.
Slovenian: in vsebina pakiranja Filmsko obložene tablete (tablete) so oranžasto rjave, ovalne, izbočene, z vtisnjeno oznako S2 na eni strani.
English: The child must take Darunavir Krka d.d.
Slovenian: - Otrok mora zdravilo Darunavir Krka d.d.
English: Some side effects are typical for anti-HIV medicines in the same family as Darunavir Krka d.d..
Slovenian: Nekateri neželeni učinki so značilni za skupino zdravil proti okužbi s HIV, v katero sodi tudi zdravilo Darunavir Krka d.d..
English: Dose for children 3 years of age and above, weighing more than 40 kilograms who have taken antiretroviral medicines before (your child's doctor will determine this) The dose is either: 800 milligram Darunavir Krka d.d.
Slovenian: Odmerek za otroke, stare 3 leta ali več in s telesno maso najmanj 40 kg, ki so že prejemali protiretrovirusna zdravila (to bo določil otrokov zdravnik) Odmerek je lahko: - 800mgzdravila Darunavir Krka d.d.
English: -The other ingredients arecellulose,microcrystalline;crospovidone, hydroxypropylcellulose; silica, colloidal anhydrous; silicified microcrystalline cellulose(cellulose,microcrystalline; silica, colloidal anhydrous)and magnesium stearate (E470b)in the tablet core and poly(vinyl alcohol), macrogol, titanium dioxide (E171), talc (E553b), yellow iron oxide (E172) -only for 400mgfilm-coated tablets and red iron oxide (E172)in film coating.
Slovenian: hidroksipropilceluloza, brezvodni koloidni silicijev dioksid, silicizirana mikrokristalna celuloza (mikrokristalna celuloza, brezvodni koloidni silicijev dioksid) in magnezijev stearat (E470b) v jedru tablete ter polivinilalkohol, makrogol, titanov dioksid (E171), smukec (E553b), rumeni železov oksid (E172) - samo v 400 mg filmsko obloženih tabletah, in rdeči železov oksid (E172) v filmski oblogi.
English: d.d.
Slovenian: Krka d.d.
English: Dasatinib Nilotinib Vinblastine Vincristine
Slovenian: ZDRAVILAZDELOVANJEM NA NOVOTVORBE dasatinib nilotinib vinblastin vinkristin everolimus irinotekan
English: that the lowest possible dose of digoxin should initially be prescribed in case digoxin is given to patients on darunavir/ritonavir therapy.
Slovenian: Zaradi majhne terapevtske širine digoksina se priporoča, da bolniki, ki sočasno prejemajo zdravili darunavir/ritonavir, na začetku prejemajo najnižji možni odmerek digoksina.
English: 400 mg and 800 mg tablets can be used to construct the once daily 800 mg regimen.
Slovenian: 400 mg in 800 mg tablete lahko uporabljate za režim odmerjanja 800 mg enkrat na dan.