FrancophonIA/ELRC3.0 huggingface dataset:
English: • Oral contraceptives (medicines to prevent pregnancy) It is important you take Cholestagel at least 4 hours after you take the oral contraceptive to ensure that the effectiveness of the contraceptive is not affected.
Estonian: Suukaudse rasestumisvastase preparaadi tõhususe säilitamiseks on oluline, et te võtate Cholestagel'i vähemalt 4 tundi pärast kombineeritud suukaudse rasestumisvastase tableti võtmist;
English: No interaction was observed when Cholestagel was administered four hours after glyburide.
Estonian: Koostoimeid ei täheldatud Cholestagel'i manustamisel neli tundi pärast gliburiidi.
English: The recommended dose for Cholestagel is 3 tablets taken twice a day with meals or 6 tablets a day with a meal.
Estonian: Soovitatav Cholestagel'i annus on 3 tabletti kaks korda päevas koos toiduga või 6 tabletti päevas koos toiduga.
English: Reductions were also seen for non-HDL-C, Total-C and Apo B. A small 5%, non-significant increase in triglycerides was noted.
Estonian: Täheldati triglütseriidide vähest (5%), mitteolulist tõusu.
English: • Antidiabetic medications (medicines used to treat diabetes, such as metformin extended-release (ER) tablets, glimepiride, glipizide, pioglitazone, repaglinide or glyburide).
Estonian: • diabeedivastased ravimid (suhkurtõve raviks kasutatavad ravimid nagu toimeainet prolongeeritult vabastavad metformiini tabletid, glimepiriid, glipisiid, pioglitasoon, repagliniid või gliburiid); kui te võtate suhkurtõve ravimeid, peate nõu pidama oma arstiga, et ta saaks teid hoolikalt jälgida; oluline on, et te võtaksite glimepiriidi ja glipisiidi vähemalt 4 tundi enne Cholestagel'i;
English: The recommended starting dose of Cholestagel is 6 tablets per day taken as 3 tablets twice per day with meals or 6 tablets once per day with a meal.
Estonian: Cholestagel'i soovituslik algannus on 6 tabletti päevas: 3 tabletti kaks korda päevas koos toiduga või 6 tabletti üks kord päevas koos toiduga.
English: NAME OF THE MEDICINAL PRODUCT Cholestagel 625 mg film-coated tablets
Estonian: Cholestagel, 625 mg õhukese polümeerikattega tabletid
English: High density polyethylene bottles with a polypropylene cap.
Estonian: Kõrgtihedusega polüetüleenpudelid koos polüpropüleenkorgiga väliskarbita.
English: Cholestagel predominantly binds hydrophobic bile acids.
Estonian: Cholestagel seob peamiselt hüdrofoobseid sapphappeid.
English: This leaflet was last revised in
Estonian: Infoleht on viimati kooskõlastatud Muud teabeallikad
English: Interaction with ciclosporin
Estonian: Koostoime tsüklosporiiniga
English: SANOFI BULGARIA EOOD Tел: +359 (0)2 970 53 00
Estonian: Tел: +359 (0)2 970 53 00
English: The incidence of intestinal obstruction is likely to be increased among patients with a history of bowel obstruction or removal.
Estonian: Varasema soolesulgusega või resetseeritud soolega patsientidel on soolesulguse tekkesagedus tõenäoliselt suurem.
English: NAME OF THE MEDICINAL PRODUCT Cholestagel 625 mg film-coated tablets Colesevelam
Estonian: Cholestagel 625 mg õhukese polümeerikattega tabletid Kolesevelaam
English: Package sizes are: 24 tablets (1 X 24)
Estonian: Pakendite suurused: 24 tabletti (1 × 24) 100 tabletti (2 × 50) 180 tabletti (1 × 180)
English: INFORMATION IN BRAILLE Cholestagel
Estonian: TEAVE BRAILLE' KIRJAS (PUNKTKIRJAS)
English: No interaction was observed when glimepiride was taken at least 4 hours before colesevelam.
Estonian: Glimepiriidi manustamisel 4 tundi enne kolesevelaami ei täheldatud koostoimeid.
English: No interaction was observed when Cholestagel and pioglitazone were administered simultaneously in healthy volunteers
Estonian: Tervetel täiskasvanutel ei täheldatud koostoimeid Cholestagel'i ja pioglitasooni samaaegsel manustamisel.
English: Cholesterol is the sole precursor of bile acids.
Estonian: Sapphapete ainus eellane on kolesterool.
English: Anticoagulant therapy
Estonian: Antikoagulantravi
English: MARKETING AUTHORISATION NUMBER(S) EU/1/03/268/001-004
Estonian: EU/1/03/268/001 24 tabletti EU/1/03/268/002 100 tabletti EU/1/03/268/003 180 tabletti välispakendiga EU/1/03/268/004 180 tabletti välispakendita
English: Only constipation and dyspepsia were reported by a higher percentage among those receiving Cholestagel, compared with placebo.
Estonian: Platseeboga võrreldes täheldati Cholestagel'iga ravitutel sagedamini üksnes kõhukinnisust ja düspepsiat.
English: Contents of the pack and other information
Estonian: Kuidas Cholestagel'i säilitada Pakendi sisu ja muu teave
English: Not known: Intestinal obstruction*,** Musculoskeletal and connective tissue disorders Uncommon: Myalgia
Estonian: Teadmata: soolesulgus*,**
English: - Cholestagel may be prescribed on its own in addition to a diet low in fat and cholesterol when treatment with a statin (a class of cholesterol-lowering medicines that work in the liver) is inappropriate or not well tolerated.
Estonian: Cholestagel on ette nähtud esmase hüperkolesteroleemia nime all tuntud haigusseisundi ravimiseks (kui vere kolesteroolisisaldus on tõusnud) täiskasvanutel: - Cholestagel'i võib välja kirjutada lisaks vähese rasva- ja kolesteroolisisaldusega dieedile, kui ravi statiiniga (rühm kolesteroolitaset alandavaid ravimeid, mis toimivad maksas) ei ole sobinud või on vastunäidustatud.
English: During normal digestion, bile acids are secreted into the intestine.
Estonian: Normaalse seedetegevuse korral erituvad sapphapped soolestikku.
English: Without the recycling process, your liver has to make additional bile acids.
Estonian: Sapphapete ringluse puudumine sunnib maksa rohkem sapphappeid tootma.
English: Posology
Estonian: Üksikravi
English: PHARMACEUTICAL FORM AND CONTENTS 24 film-coated tablets
Estonian: RAVIMVORM JA PAKENDI SUURUS
English: If you stop taking Cholestagel Your cholesterol may increase to the level it was before treatment was started.
Estonian: Teie kolesteroolitase võib tõusta ravieelsele tasemele.
English: Anticoagulant therapy should be monitored closely in patients receiving warfarin or similar agents, since bile acid sequestrants, like Cholestagel, have been shown to reduce absorption of vitamin K and therefore interfere with warfarin's anticoagulant effect.
Estonian: On ilmnenud, et sapphapete sekvestrandid, nagu Cholestagel, alandavad K-vitamiini imendumist ning häirivad varfariini antikoagulatiivset toimet, seetõttu tuleb antikoagulantravi saavaid haigeid hoolega jälgida.
English: Paediatric population
Estonian: Ursodeoksühoolhape
English: Ελλάδα sanofi-aventis AEBE Τηλ: +30 210 900 16 00
Estonian: Τηλ: +30 210 900 1600
English: Co-administration of colesevelam and olmesartan decreases the exposure of olmesartan.
Estonian: Kolesevelaami ja olmesartaani koosmanustamine vähendab olmesartaani süsteemset saadavust.
English: This percentage may vary according to ethnic background.
Estonian: See protsent võib erineva etnilise tausta korral varieeruda.
English: Symptomatic and supportive treatment is recommended.
Estonian: Sümptomaatiline ja toetav ravi on soovitatav.
English: Other medicines and Aerius
Estonian: Muud ravimid ja Aerius
English: Patients should be informed that most people do not experience drowsiness.
Estonian: Patsiente tuleb teavitada, et enamikul inimestel ei teki uimasust.
English: The clinical relevance of these observations remains to be confirmed.
Estonian: Nende nähtuste kliiniline tähtsus vajab veel kinnitamist.
English: ● severe allergic reactions
Estonian: ● rasked allergilised reaktsioonid
English: Date of first authorisation: 15 January 2001 Date of latest renewal: 15 January 2006
Estonian: Müügiloa esmase väljastamise kuupäev: 15/01/2001 Müügiloa viimase uuendamise kuupäev: 15/01/2006
English: Therefore, caution is recommended if alcohol is taken concomitantly.
Estonian: Seetõttu soovitatakse olla ettevaatlik, kui samaaegselt tarbitakse alkoholi.
English: Not known: frequency cannot be estimated from the available data ● unusual weakness
Estonian: Teadmata: sagedust ei saa hinnata olemasolevate andmete alusel ● ebatavaline nõrkus
English: Swallow the dose of oral solution and then drink some water.
Estonian: Neelake suukaudne lahus ja seejärel jooge pisut vett.
English: The enzyme responsible for the metabolism of desloratadine has not been identified yet, and therefore, some interactions with other medicinal products cannot be fully excluded.
Estonian: Desloratadiini metaboliseeriv ensüüm ei ole veel identifitseeritud ja seetõttu ei saa täielikult välistada mõningaid koostoimeid teiste ravimitega.
English: In the event of overdose, consider standard measures to remove unabsorbed active substance.
Estonian: Üleannustamise korral rakendada standardseid meetodeid imendumata aktiivse toimeaine eemaldamiseks.
English: Children 1 through 5 years of age:
Estonian: 1...5-aastased lapsed
English: Contains mannitol and aspartame.
Estonian: Sisaldab mannitooli ja aspartaami.
English: As a precautionary measure, it is preferable to avoid the use of Aerius during pregnancy.
Estonian: Ettevaatusena on parem vältida Aeriuse kasutamist raseduse ajal.
English: Manufacturer: SP Labo N.V., Industriepark 30, B-2220 Heist-op-den-Berg, Belgium.
Estonian: Tootja: SP Labo N.V., Industriepark 30, B-2220 Heist-op-den-Berg, Belgia.
English: Desloratadine is the primary active metabolite of loratadine.
Estonian: Desloratadiin on loratadiini peamine aktiivne metaboliit.
English: Pharmacotherapeutic group: antihistamines - H1 antagonist, ATC code: R06A X27
Estonian: Farmakoterapeutiline rühm: antihistamiinsed ained - H1 antagonistid, ATC-kood: R06AX27
English: Aerius effectively controlled symptoms for 24 hours.
Estonian: Aerius kontrollis sümptomeid efektiivselt 24 tundi.
English: Very rare: the following may affect up to 1 in 10,000 people ● severe allergic reactions
Estonian: Väga harv: järgnevad kõrvaltoimed võivad esineda kuni ühel inimesel 10 000-st ● rasked allergilised reaktsioonid
English: You can take this medicine with or without food.
Estonian: Võite seda ravimit võtta koos toiduga või ilma.
English: Use caution when taking Aerius with alcohol.
Estonian: Olge ettevaatlik Aeriuse võtmisel, kui tarbite alkoholi.
English: In children below 2 years of age, the diagnosis of allergic rhinitis is particularly difficult to distinguish from other forms of rhinitis.
Estonian: Alla 2-aastaste laste diagnoosimisel on allergilist riniiti raske eristada teistest riniidi vormidest.
English: Relief of these symptoms lasts a full day and helps you to resume your normal daily activities and sleep.
Estonian: Haigustunnuste vähenemine kestab kogu päeva ning võimaldab teile taas normaalse päevase tegevuse ja rahuliku une.
English: In case an oral measuring syringe is provided with the bottle of oral solution, you can alternatively use it to take the appropriate amount of oral solution.
Estonian: Juhul kui suukaudse lahuse pudeliga on kaasas mõõdikuga suusüstal, võite te seda alternatiivselt kasutada vastava koguse suukaudse lahuse mõõtmiseks.
English: This medicine is for oral use.
Estonian: See ravim on suukaudseks kasutamiseks.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from Aerius therapy taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Estonian: Rinnaga toitmise katkestamine või ravi katkestamine/jätkamine Aeriusega tuleb otsustada, arvestades imetamise kasu lapsele ja ravi kasu naisele.
English: In the case of severe renal insufficiency, Aerius should be used with caution (see section 5.2).
Estonian: Raske neerupuudulikkuse korral tuleb Aeriust kasutada ettevaatusega (vt lõik 5.2).
English: Excipient(s) with known effect: This medicine contains mannitol and aspartame (E951).
Estonian: Teadaolevat toimet omav(ad) abiaine(d) See ravim sisaldab mannitooli ja aspartaami (E951).
English: In each trial, the effects were sustained over the 24 hour dosing interval.
Estonian: Kõigis uuringutes püsis efekt kogu 24-tunnise annustamisintervalli kestel.
English: The prescriber should be aware that most cases of rhinitis below 2 years of age are of infectious origin (see section 4.4) and there are no data supporting the treatment of infectious rhinitis with Aerius.
Estonian: Ravimit ordineerides tuleb arvestada sellega, et alla 2-aastastel lastel on riniit enamikel juhtudel infektsioosse päritoluga (vt lõik 4.4) ja puuduvad andmed, mis toetaksid infektsioosse riniidi ravi Aeriusega.
English: Detailed information on this medicine is available on the European Medicines Agency website http://www.ema.europa.eu.
Estonian: Täpne teave selle ravimpreparaadi kohta on Euroopa Ravimiameti kodulehel http://www.ema.europa.eu.
English: The adverse event profile associated with overdosage, as seen during post-marketing use, is similar to that seen with therapeutic doses, but the magnitude of the effects can be higher.
Estonian: Turuletulekujärgsel kasutamisel üleannustamisega seostatud kõrvaltoimed on sarnased raviannustega nähtule, kuid mõjude tugevus võib olla suurem.
English: ● yellowing of the skin and/or eyes
Estonian: ● naha ja/või silmavalgete kollaseks muutumine
English: If you notice any of these serious side effects, stop taking the medicine and seek urgent medical advice straight away.
Estonian: Kui märkate mõnda neist tõsistest kõrvaltoimetest, siis lõpetage ravimi võtmine ja helistage kohe kiirabisse.
English: In adolescents, headache was the most commonly reported side effect.
Estonian: Noorukitel oli peavalu kõige sagedamini esinenud kõrvaltoime.
English: ● abnormal behaviour
Estonian: ● ebanormaalne käitumine
English: For urticaria, the duration of treatment may be variable from patient to patient and therefore you should follow the instructions of your physician.
Estonian: Urtikaaria ravi kestus võib olla sõltuvalt patsiendist erinev, mistõttu peate järgima oma arstilt saadud vastavaid juhiseid.
English: At the recommended dose, this medicine is not expected to affect your ability to drive or use machines.
Estonian: Selle ravimi kasutamisel soovitatud annuses ei eeldata sellel olevat mõju teie võimele juhtida autot või käsitseda masinaid.
English: Aerius tablets effectively controlled symptoms for 24 hours.
Estonian: Aeriuse tabletid kontrollisid sümptomeid efektiivselt 24 tundi.
English: The degree of accumulation of desloratadine was consistent with its half-life (approximately 27 hours) and a once daily dosing frequency.
Estonian: Desloratadiini kumulatsiooniaste on vastavuses tema poolväärtusajaga (umbes 27 tundi) ja annustamissagedusega üks kord päevas.
English: What Aerius contains
Estonian: Mida Aerius sisaldab
English: In a clinical trial with 578 adolescent patients, 12 through 17 years of age, the most common adverse event was headache; this occurred in 5.9 % of patients treated with desloratadine and 6.9 % of patients receiving placebo.
Estonian: Kliinilises uuringus, mis hõlmas 578 patsienti vanuses 12 kuni 17 aastat, oli kõige sagedamini esinev kõrvaltoime peavalu; see ilmnes 5,9%-l patsientidest, keda raviti desloratadiiniga, ning 6,9%-l patsientidest, kes said platseebot.
English: The presence of food prolongs Tmax for desloratadine from 2.5 to 4 hours and Tmax for 3-OHdesloratadine from 4 to 6 hours.
Estonian: Desloratadiini Tmax pikeneb toidu mõjul 2,5 kuni 4 tundi ja 3-OH-desloratadiini Tmax 4 kuni 6 tundi.
English: The safety of desloratadine in children 2- to 11-years of age who are poor metabolisers is the same as in children who are normal metabolisers.
Estonian: Desloratadiini ohutus 2…11-aastastel nõrga metabolisatsiooniga lastel on sama, mis normaalse metabolismiga lastel.
English: The absence of upper respiratory tract infection or structural abnormalities, as well as patient history, physical examinations, and appropriate laboratory and skin tests should be considered.
Estonian: Arvestada tuleb ülemiste hingamisteede infektsiooni või strukturaalsete kõrvalekallete puudumist, patsiendi anamneesi, füüsilist seisundit ja vastavate laboratoorsete ja nahatestide tulemusi.
English: Desloratadine is moderately bound (83 % - 87 %) to plasma proteins.
Estonian: Desloratadiin seondub mõõdukalt plasma valkudega (83...87%).
English: Although most people do not experience drowsiness, it is recommended not to engage in activities requiring mental alertness, such as driving a car or operating machinery until you have established your own response to the medicinal product.
Estonian: Kuigi enamikul inimestel ei teki uimasust, soovitatakse mitte tegeleda vaimset erksust nõudvate tegevustega, nt autojuhtimine või masinate käsitsemine, enne kui te olete kindlaks teinud ravimpreparaadi mõju endale.
English: A large amount of data on pregnant women (more than 1,000 pregnancy outcomes) indicate no malformative nor foeto/ neonatal toxicity of desloratadine.
Estonian: Suur hulk rasedate kohta saadud andmeid (rohkem kui 1000 raseda andmed) näitab, et desloratadiini kasutamisel ei esine väärarenguid ega kahjulikku toimet lootele/vastsündinule.
English: The lack of carcinogenic potential was demonstrated in studies conducted with desloratadine and loratadine.
Estonian: Kartsinogeensuse puudumine on näidatud desloratadiiniga ja loratadiiniga tehtud uuringutes.
English: How Aerius works
Estonian: Kuidas Aerius toimib
English: When given at the recommended doses, the plasma concentrations of desloratadine (see section 5.2) were comparable in the paediatric and adult populations.
Estonian: Soovitatud annuses olid desloratadiini plasmakontsentratsioonid (vt lõik 5.2) laste ja täiskasvanute populatsioonis võrreldavad.
English: Nevertheless, as there is individual variation in response to all medicinal products, it is recommended that patients are advised not to engage in activities requiring mental alertness, such as driving a car or using machines, until they have established their own response to the medicinal product.
Estonian: Sellest hoolimata, kuna kõik ravimpreparaadid mõjuvad inimestele erinevalt, siis soovitatakse patsiente nõustada mitte tegelema vaimset erksust nõudvate tegevustega, nagu nt autojuhtimine või masinate käsitsemine, enne kui nad on kindlaks teinud ravimpreparaadi mõju endale.
English: ● weight increased, increased appetite
Estonian: ● kehakaalu suurenemine, suurenenud söögiisu
English: In both studies, changes in exposure (AUC and Cmax) of desloratadine and 3-hydroxydesloratadine were not clinically relevant.
Estonian: Kummaski uuringus ei olnud muutused desloratadiini ega 3-hüdroksüdesloratadiini ekspositsioonis (AUC ja Cmax) kliiniliselt olulised.
English: The dose of orodispersible tablet is placed in the mouth where it will disperse immediately.
Estonian: Suus dispergeeruva tableti annus asetatakse suhu, kus see otsekohe lahustub.
English: However, cases of alcohol intolerance and intoxication have been reported during post-marketing use.
Estonian: Kuid turuletulekujärgselt on teatatud alkoholi talumatuse ja mürgistuse juhtudest.
English: The effects of desloratadine in poor metabolisers < 2 years of age have not been studied.
Estonian: Desloratadiini toimet nõrga metabolisatsiooniga < 2-aastastel ei ole uuritud.
English: In two placebo-controlled six week trials in patients with chronic idiopathic urticaria, Aerius was effective in relieving pruritus and decreasing the size and number of hives by the end of the first dosing interval.
Estonian: Kahes platseebokontrollitud 6-nädalases kroonilise idiopaatilise urtikaaria uuringus vähendas Aerius efektiivselt sügelust ja kuplade suurust ning arvu juba esimese ravipäeva lõpuks.
English: It helps control your allergic reaction and its symptoms.
Estonian: Ravim aitab allergilist reaktsiooni ja haigustunnuseid kontrolli all hoida.
English: ● aggression
Estonian: ● agressiivsus
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Estonian: Kui te olete rase, imetate, arvate end olevat rase või kavatsete rasestuda, pidage enne selle ravimi võtmist nõu oma arsti või apteekriga.
English: The effect of desloratadine on newborns/infants is unknown.
Estonian: Desloratadiini toime vastsündinutele/imikutele on teadmata.
English: Treatment was well tolerated as documented by clinical laboratory tests, vital signs, and ECG interval data, including QTc.
Estonian: Ravi oli hästi talutav, mida kinnitasid kliiniliste laboriuuringute, haige üldseisundi ja EKG intervalli näidud, sh QTc.
English: What Aerius is Aerius contains desloratadine which is an antihistamine.
Estonian: Mis ravim on Aerius Aerius sisaldab desloratadiini, mis on antihistamiin.
English: However, common side effects in children less than 2 years of age were diarrhoea, fever and insomnia while in adults, fatigue, dry mouth and headache were reported more often than with a dummy tablet.
Estonian: Siiski olid alla 2-aastastel lastel sagedased kõrvaltoimed kõhulahtisus, palavik ja unetus, samal ajal kui täiskasvanutel teatati väsimust, suukuivust ja peavalu sagedamini kui toimeta tableti korral.
English: Common in children less than 2 years of age: the following may affect up to 1 in 10 children
Estonian: Sage alla 2-aastastel lastel: järgnevad kõrvaltoimed võivad esineda kuni ühel lapsel 10-st
English: Desloratadine has demonstrated antiallergic properties from in vitro studies.
Estonian: Desloratadiini antiallergilised omadused on näidatud in vitro uuringutega.
English: Intermittent allergic rhinitis is defined as the presence of symptoms for less than 4 days per week or for less than 4 weeks.
Estonian: Allergilist riniiti loetakse vahelduvaks, kui sümptomid ilmnevad vähem kui 4 päeval nädalas või vähem kui 4 nädalat.
English: Non-clinical studies conducted with desloratadine and loratadine demonstrated that there are no qualitative or quantitative differences in the toxicity profile of desloratadine and loratadine at comparable levels of exposure to desloratadine.
Estonian: Desloratadiini ja loratadiini mittekliinilised uuringud ei näita kvalitatiivseid või kvantitatiivseid erinevusi desloratadiini ja sellega võrreldaval tasemel loratadiini toksilisuse profiilis.
English: The bioavailability of desloratadine was dose proportional over the range of 5 mg to 20 mg.
Estonian: Desloratadiini biosaadavus sõltus proportsionaalselt annusest vahemikus 5 mg kuni 20 mg.
English: As Aerius oral solution contains the same concentration of desloratadine, no bioequivalence study was required and it is expected to be equivalent to the syrup and tablet.
Estonian: Kuna Aeriuse suukaudne lahus sisaldab desloratadiini samas kontsentratsioonis, ei ole bioekvivalentsusuuringud nõutud ning suukaudne lahus on eeldatavasti bioekvivalentne siirupi ja tabletiga.
English: Fertility There are no data available on male and female fertility.
Estonian: Fertiilsus Nii meeste kui ka naiste fertiilsuse kohta andmed puuduvad.
English: Approximately 6 % of adults and children 2- to 11-year old are phenotypic poor metabolisers of desloratadine and exhibit a higher exposure (see section 5.2).
Estonian: Umbes 6% täiskasvanutest ja 2…11-aastastest lastest on fenotüübilt desloratadiini nõrgad metaboliseerijad ja nad on ravimile rohkem eksponeeritud (vt lõik 5.2).
English: If you take more Aerius than you should
Estonian: Kui te võtate Aeriust rohkem kui ette nähtud
English: There are no known interactions of Aerius with other medicines.
Estonian: Aeriuse võimalike koostoimete kohta teiste ravimitega andmed puuduvad.
English: Treatment with Aerius also significantly reduced interference with sleep and daytime function, as measured by a four-point scale used to assess these variables.
Estonian: Ravi Aeriusega vähendas ühtlasi märkimisväärselt unehäireid ja päevaste tegevuste häiritust, mida hinnati 4-punktilisel skaalal.
English: Desloratadine plasma concentrations can be detected within 30 minutes of administration.
Estonian: Desloratadiini plasmakontsentratsiooni on võimalik mõõta 30 minutit pärast manustamist.
English: An improvement in pruritus of more than 50 % was observed in 55 % of patients treated with desloratadine compared with 19 % of patients treated with placebo.
Estonian: Üle 50% vähenes sügelemine 55%-l desloratadiiniga ravitud patsientidest, võrreldes 19% platseeboga ravitud patsientidega.