FrancophonIA/ELRC3.0 huggingface dataset:
English: Nelfinavir must not be administered concurrently with terfenadine, astemizole or cisapride because of the potential for serious and/or life-threatening cardiac arrhythmias.
Slovenian: Nelfinavir se sočasno z terfenadinom, astemizolom ali cisapridom ne sme dajati, ker obstaja možnost, da povzroči nevarne in/ali življenjsko ogrožujoče srčne aritmije.
English: Other possible side effects, where you should talk to your doctor If you get any of the side effects on this list, or if you notice any side effects not listed in this leaflet, please tell your doctor.
Slovenian: Drugi neželeni učinki, o katerih morate obvestiti vašega zdravnika Če se pri vas pojavi katerikoli od naštetih neželenih učinkov ali če opazite katerikoli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika.
English: The table also shows the recommended total number of Viracept tablets that children will be given each day based on their weight.
Slovenian: Preglednica prav tako prikazuje priporočeno skupno število Viracept tablet, ki jih bodo otroci prejeli vsak dan glede na njihovo telesno maso.
English: 14 2-13 years
Slovenian: 2-13 let
English: • A severe form of rash (erythema multiforme).
Slovenian: • huda oblika izpuščaja (multiformni eritem),
English: Pharmacokinetic data are also available for 86 patients (age 2 to 12 years) who received VIRACEPT 25-35 mg/kg TID in Study AG1343-556.
Slovenian: Na voljo so tudi farmakokinetični podatki za 86 bolnikov (starih od 2 do 12 let), ki so prejemali zdravilo VIRACEPT 25 - 35 mg/kg trikrat na dan v študiji AG1343-556.
English: Viracept is used with other ‘anti-retroviral' medicines to:
Slovenian: Zdravilo Viracept se uporablja v kombinaciji z drugimi »protiretrovirusnimi« zdravili zato, da:
English: How much you take each time (in grams)
Slovenian: odmerek, ki ga vsakič vzamete (v gramih)
English: Although study 542 showed no statistically significant differences between the two regimens in efficacy in a predominantly antiretroviral naïve patient population, the significance of these findings for antiretroviral experienced patients is unknown.
Slovenian: Čeprav študija pri 542 bolnikih, pretežno še nezdravljenih s protiretrovirusnimi zdravili, ni pokazala statistično značilnih razlik med dvema režimoma odmerjanja v učinkovitosti, pa pomembnost teh ugotovitev pri bolnikih, ki so že bili zdravljeni s protiretrovirusnimi zdravili, ni znana.
English: If the mixture is not consumed immediately, it must be stored under refrigeration, but storage must not exceed 6 hours.
Slovenian: Če mešanica ni zaužita takoj, se lahko shranjuje v hladilniku, vendar ne več kot 6 ur.
English: over 22 kg * Children with these weights will be given an uneven number of tablets during the day.
Slovenian: nad 22 kg * Otroci s temi telesnimi masami ne bodo prejeli enakega števila tablet čez dan.
English: One major and several minor oxidative metabolites were found in plasma.
Slovenian: V plazmi so našli enega glavnega in več manj pomembnih oksidiranih presnovkov.
English: SPECIAL STORAGE CONDITIONS Do not store above 30°C Store in the original container
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Shranjujte pri temperaturi do 30 °C Shranjujte v originalnem vsebniku
English: The signs may include difficulty in breathing, fever, itching, swelling of the face and skin rashes that can sometimes form blisters.
Slovenian: Znaki lahko vključujejo težave z dihanjem, zvišano telesno temperaturo, srbež, zateklost obraza in kožne izpuščaje, ki lahko včasih povzročijo mehurje.
English: Many patients had confounding medical conditions, some of which required therapy with agents that have been associated with the development of diabetes or hyperglycaemia.
Slovenian: Mnogi od teh bolnikov so imeli dodatna obolenja, nekatere od njih je bilo treba zdraviti z učinkovinami, povezanimi z razvojem sladkorne bolezni ali hiperglikemije.
English: Date of latest renewal: 23 January 2008
Slovenian: Datum zadnjega podaljšanja dovoljenja za promet: 23.1.2008
English: • You are allergic to nelfinavir or to any of the other ingredients (listed in Section 6 ‘Further information').
Slovenian: • če ste alergični (preobčutljivi) na nelfinavir ali katerokoli sestavino zdravila (naštete so v poglavju 6 »Dodatne informacije«),
English: In vitro: HIV isolates with reduced susceptibility to nelfinavir have been selected in vitro.
Slovenian: In vitro: izolati HIV z zmanjšano občutljivostjo za nelfinavir so bili izbrani in vitro.
English: The virological failure was greater in the nelfinavir group (17 %) than in the fosamprenavir/ritonavir group (7 %).
Slovenian: Virološki neuspeh je bil večji v skupini, zdravljeni z nelfinavirjem (17 %), kot v skupini, zdravljeni s fosamprenavirjem/ritonavirjem (7 %).
English: 270 film-coated tablets
Slovenian: 270 filmsko obloženih tablet
English: A higher risk of lipodystrophy has been associated with individual factors such as older age, and with drug related factors such as longer duration of antiretroviral treatment and associated metabolic disturbances.
Slovenian: Večje tveganje za lipodistrofijo povezujejo s posameznimi dejavniki, kot so višja starost, in z dejavniki povezanimi z zdravilom, kot je dalj časa trajajoče protiretrovirusno zdravljenje in s tem povezane presnovne motnje.
English: Since increased concentrations of HMG-CoA reductase inhibitors may cause myopathy, including rhabdomyolysis, the combination of these medicinal products with nelfinavir is not recommended.
Slovenian: Ker povečane koncentracije zaviralcev reduktaze HMG-CoA lahko povzročijo miopatijo, vključno z rabdomiolizo, kombinacija teh zaviralcev z nelfinavirjem ni priporočljiva.
English: • This medicine contains aspartame, which is a source of phenylalanine.
Slovenian: • Zdravilo vsebuje sladilo aspartam, ki je izvor fenilalanina.
English: The cause and long-term health effects of these conditions are not known at this time.
Slovenian: Vzroki teh stanj in njihovi dolgoročni vplivi na zdravje za zdaj niso znani.
English: Two studies have compared the safety and efficacy of nelfinavir (unboosted) with ritonavir- boosted protease inhibitors, each in combination with other antiretroviral agents.
Slovenian: Dve študiji sta primerjali varnost in učinkovitost nelfinavirja (brez podporne terapije) z zaviralci proteaz ob podporni terapiji z ritonavirjem, vsakega v kombinaciji z drugimi protiretrovirusnimi učinkovinami.
English: Tell your doctor or pharmacist if you are taking or have recently taken any other medicines.
Slovenian: Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo.
English: 300 film-coated tablets
Slovenian: 300 filmsko obloženih tablet
English: Patients should be instructed that VIRACEPT is not a cure for HIV infection, that they may continue to develop infections or other illnesses associated with HIV disease, and that VIRACEPT has not been shown to reduce the risk of transmission of HIV disease through sexual contact or blood contamination.
Slovenian: Bolnikom moramo povedati, da zdravilo VIRACEPT ne ozdravi okužbe z virusom HIV, da se lahko razvoj okužb ali drugih bolezni, povezanih s HIV, nadaljuje, in da zdravilo VIRACEPT ne odpravi tveganja prenosa okužbe s HIV s spolnim stikom ali okuženo krvjo.
English: A 49 %-69 % increase was observed in AUC of nelfinavir in the hepatically impaired group (Child-Turcotte Classes A to C) compared to the healthy group.
Slovenian: Opaženo je bilo 49- do 69 % povečanje AUC nelfinavirja v skupini z motnjami jetrnega delovanja z okvaro (Child-Turcotte razredi od A do C) v primerjavi z zdravo skupino.
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, 4.2.)
Slovenian: Izdaja zdravila je le pod omejenimi pogoji in na recept (Glej Dodatek I: Povzetek glavnih značilnosti zdravila, 4.2).
English: In subjects with normal CYP2C19 activity, plasma levels of this metabolite are approximately 25 % of the total plasma nelfinavir-related concentration.
Slovenian: Pri bolnikih z normalno aktivnostjo CYP2C19 je raven tega presnovka v plazmi približno 25 % celotne plazemske koncentracije nelfinavirja in njegovih presnovkov.
English: The absorption of nelfinavir may be reduced in situations where the gastric pH is increased irrespective of cause.
Slovenian: Absorpcija nelfinavirja se lahko zmanjša, če se poveča želodčni pH, neglede na vzrok.
English: Children with weights between 10.5-12 kg, 12-14 kg and 18-22 kg will receive a different number of tablets with each meal.
Slovenian: Otroci s telesno maso 10,5-12 kg, 1214 kg in 18-22 kg bodo ob vsakem obroku prejeli različno število tablet.
English: • Pimozide (used for mental health problems)
Slovenian: • pimozid (za psihične težave),
English: If nelfinavir is co-administered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Slovenian: Če se nelfinavir daje sočasno s parenteralno obliko midazolama, se mora to izvesti v enoti za intenzivno nego ali podobnem okolju, ki zagotavlja natančno klinično spremljanje in ustrezno medicinsko oskrbo v primeru respiratorne depresije in/ali podaljšane sedacije.
English: Serious and non-serious adverse reactions from post-marketing spontaneous reports (where nelfinavir was taken as the sole protease inhibitor or in combination with other antiretroviral therapy), not mentioned previously in section 4.8, for which a causal relationship to nelfinavir cannot be excluded, are summarised below.
Slovenian: Resni in neresni neželeni učinki iz spontanega poročanja v obdobju trženja zdravila (nelfinavir uporabljan kot edini zaviralec proteaze ali v kombinaciji z drugimi protiretrovirusnimi zdravili), ki v predhodno navedenih neželenih učinkih v poglavju 4.8 niso omenjeni, so povzeti spodaj.
English: Renal and hepatic impairment: there are no data specific for HIV positive patients with renal impairment and therefore specific dosage recommendations cannot be made (see section 4.4).
Slovenian: Ledvična in jetrna okvara: za HIV pozitivne bolnike z ledvično okvaro podatkov ni na voljo, zato posebnih priporočil o odmerjanju ni (glejte poglavje 4.4).
English: Combination with other medicinal products: Caution is advised whenever VIRACEPT is coadministered with agents that are inducers or inhibitors and/or substrates of CYP3A4; such combinations may require dose adjustment (see also sections 4.3 and 4.8).
Slovenian: Kombinacija z drugimi zdravili: previdnost je potrebna pri jemanju zdravila VIRACEPT skupaj z snovmi, ki so induktorji ali zaviralci, in/ali substrati za CYP3A4; takšne kombinacije lahko potrebujejo prilagoditev odmerka (glejte tudi poglavji 4.3 in 4.8).
English: • When your child weighs 18 kg or less, you must provide the tablets three times a day.
Slovenian: • Kadar vaš otrok tehta 18 kg ali manj, mu morate dati tablete trikrat na dan.
English: Nelfinavir was found to be active against a broad range of laboratory strains and clinical isolates of HIV-1 and the HIV-2 strain ROD.
Slovenian: Nelfinavir je bil učinkovit proti širokemu obsegu laboratorijskih linij in kliničnih izolatov HIV-1 in HIV-2 linij ROD.
English: Proportion of patients with HIV RNA below LOQ (sensitive and ultrasensitive assays) at Week 48 Assay
Slovenian: Delež bolnikov s HIV RNA pod mejo detekcije (občutljive in zelo občutljive metode) v 48. tednu Metoda
English: Patients older than 13 years: VIRACEPT 250 mg tablets are recommended for adults and older children (see Summary of Product Characteristics for VIRACEPT 250 mg tablets).
Slovenian: Bolniki, starejši od 13 let: tablete VIRACEPT 250 mg so priporočljive za odrasle in starejše otroke (glejte Povzetek glavnih značilnosti za tablete VIRACEPT 250 mg).
English: Elimination: oral clearance estimates after single doses (24-33 l/h) and multiple doses (26-61 l/h) indicate that nelfinavir exhibits medium to high hepatic bioavailability.
Slovenian: Izločanje: ocene očistka po peroralnih enkratnih odmerkih (24 do 33 l/h) in večkratnih odmerkih (26 do 61 l/h) nakazujejo srednje do veliko biološko uporabnost nelfinavirja v jetrih.
English: Once dispersed, the cloudy bluish liquid should be thoroughly mixed and consumed immediately.
Slovenian: Po raztopitvi, je treba motno modrikasto tekočino temeljito premešati in takoj zaužiti.
English: For adults or children unable to take tablets, Viracept tablets may be put into water and taken as follows:
Slovenian: Odrasli ali otroci, ki ne morejo pogoltniti tablet, lahko Viracept raztopijo v vodi na naslednji način:
English: • Put the tablets in a half cup of water and stir with a spoon.
Slovenian: • tableto dajte v pol kozarca vode in premešajte z žlico,
English: The following side effects may happen with this medicine.
Slovenian: Pri uporabi tega zdravila se lahko pojavijo naslednji neželeni učinki.
English: Cmax fold increase Increase in Tmax (hr)
Slovenian: Povečanje Tmax (h)
English: Pharmacotherapeutic group:direct acting antivirals, ATC code: J05AE04.
Slovenian: Farmakoterapevtska skupina: zdravila za sistemsko zdravljenje virusnih infekcij; Oznaka ATC: J05AE04.
English: AG1343-524 20 (19-28) mg/kg TID
Slovenian: AG1343-524 20 (19-28) mg/kg
English: There are not sufficient data from patients with liver impairment and therefore specific dose recommendations cannot be made (see section 5.2).
Slovenian: Ustreznih podatkov za bolnike z jetrno okvaro ni, zato ni posebnih priporočil o odmerjanju (glejte poglavje 5.2).
English: • Low numbers of a type of white blood cell that fights infections (neutrophils).
Slovenian: • zmanjšano število belih krvnih celic, ki se borijo proti okužbam (nevtrofilci),
English: If you have haemophilia type A or B, in rare cases your bleeding may increase.
Slovenian: Če imate hemofilijo tipa A ali B, se lahko v redkih primerih krvavitev poveča.
English: Dosage adjustment for midazolam should be considered, especially if more than a single dose of midazolam is administered
Slovenian: Razmisliti je treba o prilagoditvi odmerka midazolama, zlasti, če je bil dan več kot en odmerek midazolama.
English: The difference between morning and afternoon or evening trough concentrations for the TID and BID regimens was also observed in healthy volunteers who were dosed at precise 8- or 12-hour intervals.
Slovenian: Razliko med jutranjimi in popoldanskimi ali večernimi najnižjimi koncentracijami pred naslednjim odmerkom pri odmerjanju dvakrat in trikrat na dan so opazili tudi pri zdravih prostovoljcih, ki so prejeli odmerek v točno določenih 8- ali 12- urnih intervalih.
English: • Warfarin (for lowering the chance of blood clots in your body)
Slovenian: • varfarin (za zmanjševanje zlepljanja krvnih ploščic v vašem telesu),
English: If you have haemophilia type A or B, in rare
Slovenian: Če imate hemofilijo tipa A ali B, se lahko v redkih
English: Antiviral activity in vitro: the antiviral activity of nelfinavir in vitro has been demonstrated in both HIV acute and chronic infections in lymphoblastoid cell lines, peripheral blood lymphocytes and monocytes/macrophages.
Slovenian: Protivirusna aktivnost in vitro: protivirusno aktivnost nelfinavirja in vitro so ugotovili tako v akutnih kot tudi v kroničnih okužbah s HIV v limfoblastoidnih celičnih linijah, limfocitih periferne krvi in monocitih/makrofagih.
English: Concomitant use of protease inhibitors with lovastatin or simvastatin is contraindicated.
Slovenian: Sočasna uporaba zaviralcev proteaz z lovastatinom ali simvastatinom je kontraindicirana.
English: In some patients with advanced HIV infection and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Slovenian: Pri nekaterih bolnikih z napredovalo okužbo s HIV in z oportunistično okužbo v anamnezi se lahko kmalu po začetku anti-HIV zdravljenja pojavijo znaki in simptomi vnetja povezani s prejšnjimi okužbami.
English: This medicinal product must not be mixed with acidic substances due to taste (see section 4.2).
Slovenian: Zdravila zaradi okusa ne smemo mešati s kislimi snovmi (glejte poglavje 4.2).
English: Among other things, very large doses of Viracept might cause problems with your heart rhythm.
Slovenian: Poleg drugih simptomov, lahko zelo veliki odmerki zdravila Viracept povzročijo motnje srčnega ritma.
English: Treatment with Viracept does not stop you giving HIV to others through contact with blood or sexual contact.
Slovenian: Zdravljenje z zdravilom Viracept ne preprečuje prenosa virusa HIV na druge osebe z okuženo krvjo ali spolnim stikom.
English: Driving and using machines Viracept is not likely to affect you being able to drive or use any tools or machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Zdravilo Viracept verjetno ne vpliva na sposobnost vožnje ali upravljanja z orodji ali s stroji.
English: If you have been told by your doctor that you cannot tolerate or digest some sugars (have an intolerance to some sugars), talk to your doctor before taking this medicine.
Slovenian: Če vam je zdravnik povedal, da imate intoleranco za nekatere sladkorje, se pred uporabo tega zdravila posvetujte s svojim zdravnikom.
English: Patients received VIRACEPT either three times daily or twice daily with food or with meals.
Slovenian: Bolniki so prejemali zdravilo VIRACEPT bodisi trikrat na dan ali dvakrat na dan s hrano ali z obroki.
English: Nevirapine
Slovenian: nevirapin
English: Decreases in HIV RNA observed with nelfinavir monotherapy were less pronounced and of shorter duration.
Slovenian: Zmanjšanje HIV RNA pri monoterapiji z nelfinavirjem je bilo manj izrazito in krajše.
English: Therefore the potential for QT prolongation should be considered in cases of overdose (see section 4.9).
Slovenian: Zato je pri prevelikem odmerjanju treba upoštevati možnost Q-T podaljšanja (glejte poglavje 4.9).
English: Viracept is not a cure for HIV infection.
Slovenian: Zdravilo Viracept ne ozdravi okužbe z virusom HIV.
English: HIV isolates from selected patients treated with nelfinavir alone or in combination with reverse transcriptase inhibitors were monitored for phenotypic (n=19) and genotypic (n=195, 157 of which were assessable) changes in clinical trials over a period of 2 to 82 weeks.
Slovenian: HIV izolate izbranih bolnikov, zdravljenih z nelfinavirjem samim ali v kombinaciji z zaviralci reverzne transkriptaze, so proučevali glede na fenotipske (n = 19) in genotipske (n = 195, od tega je bilo ocenljivih 157) spremembe v kliničnih preskušanjih, ki so potekale v obdobju od 2 do 82 tednov.
English: Trough drug exposures remain at least twenty fold greater than the mean IC95 throughout the dosing interval for both regimens.
Slovenian: Najnižja izpostavljenost zdravilu tik pred ponovnim odmerkom je bila vsaj dvajsetkrat večja kot srednja IC95 skozi celoten dozirni interval za obe shemi odmerjanja.
English: The majority of patients in these studies received either 750 mg TID either alone or in combination with nucleoside analogues or 1250 mg BID in combination with nucleoside analogues.
Slovenian: Večina bolnikov v teh študijah je prejela 750 mg trikrat na dan, bodisi samega ali v kombinaciji z nukleozidnimi analogi, ali 1250 mg dvakrat na dan v kombinaciji z nukleozidnimi analogi.
English: Only 1-2 % of the dose was recovered in urine, of which unchanged nelfinavir was the major component.
Slovenian: Le 1 do 2 % odmerka se izloči z urinom, največ kot nespremenjeni nelfinavir.
English: • Ask your doctor or pharmacist for advice before taking any medicine.
Slovenian: • Posvetujte se z zdravnikom ali s farmacevtom, preden vzamete katerokoli zdravilo.
English: The effects of nelfinavir (alone or combined with other antiretroviral agents) on biological markers of disease activity, CD4 cell count and viral RNA, were evaluated in several studies involving HIV-1 infected patients.
Slovenian: Učinke nelfinavirja (samega ali kombiniranega z drugimi protiretrovirusnimi učinkovinami) na biološke označevalce aktivnosti bolezni, število celic CD4 in virusno RNA, so proučevali v številnih študijah, ki so vključevale bolnike, okužene s HIV-1.
English: The estimated volumes of distribution in both animals and humans is 2-7 l/kg which exceeded total body water and suggests extensive penetration of nelfinavir into tissues.
Slovenian: Pri živalih in ljudeh so ocenjeni volumni porazdelitve (2 do 7 l/kg) presegali volumen celotne telesne tekočine, kar nakazuje obsežno prehajanje nelfinavirja v tkiva.
English: Powder with milk, formula, pudding, or water, as part of a light meal or tablet taken with a light meal
Slovenian: Prašek z mlečno formulo, pudingom ali vodo, kot del lahkega obroka, ali tableta zaužita z lahkim obrokom
English: Therapy with VIRACEPT should be initiated by a physician experienced in the management of HIV infection.
Slovenian: Zdravljenje z zdravilom VIRACEPT mora vpeljati zdravnik, ki ima izkušnje z zdravljenjem okužbe z virusom HIV.
English: Physicians should not use potent inducers of CYP 3A4 in combination with Viracept and should consider using alternatives when a patient is taking VIRACEPT (see section 4.5).
Slovenian: Zdravniki ne smejo uporabiti močnih induktorjev CYP3A4 v kombinaciji z zdravilom Viracept in morajo razmisliti o drugih možnostih zdravljenja, če bolnik jemlje zdravilo VIRACEPT (glejte poglavje 4.5).
English: Treatment emergent NRTI resistance was significantly less frequent with fosamprenavir/ritonavir compared to nelfinavir (13 % versus 57 %; p<0.001).
Slovenian: Odpornost proti potrebnemu zdravljenju z nukleozidnimi analogi zaviralcev reverzne transkriptaze (nucleoside analogue reverse transcriptase inhibitors - NRTI) je bilo značilno manj pogosto pri fosamprenavirju/ritonavirju v primerjavi z nelfinavirjem (13 % v primerjavi s 57 %; p < 0,001).
English: Clinical isolates (n=5) with decreased susceptibility to zidovudine, lamivudine, or nevirapine remain fully susceptible to nelfinavir in vitro.
Slovenian: Klinični izolati (n = 5) z zmanjšano občutljivostjo za zidovudin, lamivudin ali nevirapin ostajajo in vitro povsem občutljivi za nelfinavir.
English: • Medicines that lower stomach acid such as lansoprazole
Slovenian: • zdravila, ki zavirajo izločanje želodčne kisline, kot je lansoprazol,
English: Pregnancy, contraception and breast-feeding • Talk to your doctor before you take Viracept if you are pregnant or planning to become
Slovenian: Nosečnost, kontracepcija in dojenje • Če ste noseči ali nameravate zanositi, o tem obvestite svojega zdravnika preden začnete jemati
English: The cleavage of these viral polyproteins is essential for the maturation of infectious virus.
Slovenian: Cepitev virusnih polibeljakovin je bistvena za zorenje infektivnega virusa.
English: For younger children able to take tablets, Viracept tablets may be taken instead of the oral powder.
Slovenian: Mlajšim otrokom, ki lahko jemljejo tablete, lahko namesto peroralnega praška dajemo tablete zdravila Viracept.
English: Pharmacokinetics of nelfinavir after a single dose of 750 mg was studied in patients with liver impairment and healthy volunteers.
Slovenian: Farmakokinetika nelfinavirja po enkratnem odmerku 750 mg je bila proučevana pri bolnikih z jetrno okvaro in zdravih prostovoljcih.
English: VIRACEPT should not be co-administered with omeprazole due to a reduction in exposure to nelfinavir and its active metabolite M8 (Tert-butyl hydroxy nelfinavir).
Slovenian: Zdravila VIRACEPT ne smemo sočasno jemati z omeprazolom zaradi zmanjšane izpostavljenosti nelfinavirju in njegovemu aktivnemu presnovku M8 (terc-butil hidroksinelfinavir).
English: Cross-resistance between nelfinavir and reverse transcriptase inhibitors is unlikely because different enzyme targets are involved.
Slovenian: Navzkrižna odpornost med nelfinavirjem in zaviralci reverzne transkriptaze je zaradi različnih tarčnih encimov malo verjetna.
English: Summary of Steady-state AUC24 of nelfinavir in Paediatric Studies
Slovenian: Povzetek AUC24 nelfinavirja v stanju dinamičnega ravnovesja pri pediatričnih študijah
English: Median baseline HIV-1 RNA was 4.8 log10 copies/ml in both treatment groups.
Slovenian: Mediana začetne vrednosti HIV-1 RNK je bila 4,8 log10 kopij/ml v obeh skupinah.