FrancophonIA/ELRC3.0 huggingface dataset:
English: If a patient wishes to become pregnant or if a pregnancy occurs, treatment should be discontinued and the patient switched to insulin treatment as soon as possible.
Croatian: Ako bolesnica želi zatrudnjeti ili zatrudni, treba prekinuti liječenje i bolesnicu čim prije prebaciti na liječenje inzulinom.
English: Studies in animals have shown reproductive toxicity at high doses of sitagliptin (see section 5.3).
Croatian: Istraživanja na životinjama pokazala su reproduktivnu toksičnost sitagliptina pri visokim dozama (vidjeti dio 5.3).
English: Very common (may affect more than 1 in 10 people): low blood sugar Common: constipation
Croatian: Vrlo često (mogu se javiti u više od 1 na 10 osoba): nizak šećer u krvi Često: zatvor
English: However, because sitagliptin is primarily renally eliminated, severe hepatic impairment is not expected to affect the pharmacokinetics of sitagliptin.
Croatian: Međutim, budući da se sitagliptin primarno eliminira bubrezima, ne očekuje se da će teško oštećenje funkcije jetre utjecati na farmakokinetiku sitagliptina.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Ristfor in all subsets of the paediatric population in type 2 diabetes mellitus (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove je izuzela obvezu podnošenja rezultata ispitivanja lijeka Ristfor u svim podskupinama pedijatrijske populacije za dijabetes mellitus tipa 2 (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: In vitro and clinical data described below suggest that the risk for clinically meaningful interactions following co-administration of other medicinal products is low.
Croatian: In vitro i klinički podaci opisani niže ukazuju na nizak rizik od klinički značajnih interakcija nakon istodobne primjene s drugim lijekovima.
English: Taking this medicine in combination with medicines called sulphonylureas or with insulin can cause hypoglycaemia, which may affect your ability to drive and use machines or work without safe foothold.
Croatian: Uzimanje ovog lijeka u kombinaciji s lijekovima koji se zovu sulfonilureje ili s inzulinom, može uzrokovati hipoglikemiju, koja može utjecati na Vašu sposobnost upravljanja vozilima i rada sa strojevima ili rada bez sigurnog oslonca.
English: Gastrointestinal symptoms were reported very commonly in clinical studies and post-marketing use of metformin.
Croatian: Gastrointestinalni simptomi bili su prijavljeni vrlo često u kliničkim ispitivanjima i nakon stavljanja u promet metformina.
English: C]sitagliptin oral dose, approximately 16 % of the radioactivity was excreted as metabolites of sitagliptin.
Croatian: C]sitagliptina približno 16% radioaktivnosti izlučilo se u obliku metabolita sitagliptina.
English: The incidence of hypoglycaemia was 24.9 % for patients treated with sitagliptin, metformin, and insulin and 37.8 % for patients treated with placebo, metformin, and insulin.
Croatian: Incidencija hipoglikemije bila je 24,9% u bolesnika liječenih sitagliptinom, metforminom i inzulinom, a 37,8% u bolesnika koji su liječeni placebom, metforminom i inzulinom.
English: When starting or using such products in combination with metformin, close monitoring of renal function is necessary.
Croatian: Kad se takvi lijekovi uvode ili primjenjuju u kombinaciji s metforminom, potrebno je pažljivo praćenje funkcije bubrega
English: Do not take Ristfor if any of the above apply to you and talk with your doctor about other ways of managing your diabetes.
Croatian: Nemojte uzimati Ristfor ako se nešto od gore navedenog odnosi na Vas i razgovarajte sa svojim liječnikom o drugim načinima na koje možete kontrolirati svoju šećernu bolest.
English: Lactic acidosis, a rare but serious metabolic complication, most often occurs at acute worsening of renal function or cardiorespiratory illness or sepsis.
Croatian: Laktacidoza, rijetka, ali ozbiljna metabolička komplikacija, najčešće nastaje pri akutnom pogoršanju funkcije bubrega ili kardiorespiratornoj bolesti ili sepsi.
English: • iodinated contrast agents or alcohol-containing medicines
Croatian: • kontrastna sredstva koja sadrže jod ili lijekovi koji sadrže alkohol
English: Sitagliptin is a substrate for human organic anion transporter-3 (hOAT-3), which may be involved in the renal elimination of sitagliptin.
Croatian: Sitagliptin je supstrat humanog organskog anionskog transportera-3 (hOAT-3) koji bi mogao biti uključen u eliminaciju sitagliptina bubrezima.
English: No metabolites have been identified in humans.
Croatian: U ljudi nisu utvrđeni njegovi metaboliti.
English: Pharmacotherapeutic group: Drugs used in diabetes, Combinations of oral blood glucose lowering drugs, ATC code: A10BD07
Croatian: Farmakoterapijska skupina: Lijekovi za liječenje šećerne bolesti; kombinacije oralnih lijekova za sniženje glukoze u krvi, ATK oznaka: A10BD07
English: In a two-day study in healthy subjects, sitagliptin alone increased active GLP-1 concentrations, whereas metformin alone increased active and total GLP-1 concentrations to similar extents.
Croatian: U dvodnevnom ispitivanju u zdravih ispitanika, sitagliptin sam povisio je koncentraciju aktivnog GLP-1 dok je metformin sam povisio koncentraciju i aktivnog i ukupnog GLP-1 do sličnog opsega.
English: Multi-pack containing 196 (2 packs of 98) film-coated tablets Multi-pack containing 168 (2 packs of 84) film-coated tablets
Croatian: Višestruko pakiranje koje sadrži 196 (2 pakiranja s 98) filmom obloženih tableta Višestruko pakiranje koje sadrži 168 (2 pakiranja s 84) filmom obloženih tableta
English: Table 2: HbA1c results in placebo-controlled combination therapy studies of sitagliptin and metformin*
Croatian: Tablica 2: Rezultati HbA1c u placebom kontroliranim ispitivanjima kombinirane terapije sitagliptinom i metforminom*
English: If you are not sure, talk to your doctor, pharmacist or nurse before taking Ristfor.
Croatian: Ako niste sigurni, obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego uzmete Ristfor.
English: These changes in sitagliptin pharmacokinetics were not considered to be clinically meaningful.
Croatian: Ove promjene u farmakokinetici sitagliptina ne smatraju se klinički značajnima.
English: Since co-administration of a high-fat meal with sitagliptin had no effect on the pharmacokinetics, sitagliptin may be administered with or without food.
Croatian: Budući da istodobno uzimanje sitagliptina s punomasnim obrokom nema učinak na farmakokinetiku, sitagliptin se može uzimati s hranom ili bez nje.
English: Elimination of sitagliptin occurs primarily via renal excretion and involves active tubular secretion.
Croatian: Eliminacija sitagliptina se primarno odvija putem izlučivanja bubrezima i uključuje aktivnu tubularnu sekreciju.
English: In vitro, sitagliptin did not inhibit OAT3 (IC50=160 M) or p-glycoprotein (up to 250 M) mediated transport at therapeutically relevant plasma concentrations.
Croatian: In vitro, sitagliptin ne inhibira transport posredovan OAT3 (IC50=160 µM) ili p-glikoproteinom (do 250 µM) pri terapijski značajnim koncentracijama u plazmi.
English: • sitagliptin belongs to a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors)
Croatian: • sitagliptin pripada skupini lijekova koji se zovu DPP-4 inhibitori (inhibitori dipeptidil peptidaze-4).
English: The effects of potent CYP3A4 inhibitors in the setting of renal impairment have not been assessed in a clinical study.
Croatian: Učinci potentnih inhibitora CYP3A4 u bolesnika s oštećenjem funkcije bubrega nisu procijenjeni u kliničkom ispitivanju.
English: Pack of 50 x 1 film-coated tablets in perforated unit dose blisters.
Croatian: Pakiranje s 50 x 1 filmom obloženom tabletom u perforiranim blisterima s jediničnim dozama.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any subsequent updates of the RMP.
Croatian: Nositelj odobrenja obavljat će zadane farmakovigilancijske aktivnosti i intervencije, detaljno objašnjene u dogovorenom Planu upravljanja rizikom (RMP), koji se nalazi u Modulu 1.8.2
English: Among these patients, adverse events reported regardless of causal relationship to medicinal product occurring in at least 5 % included upper respiratory tract infection and nasopharyngitis.
Croatian: Nuspojave prijavljene u najmanje 5% tih bolesnika, bez obzira jesu li povezane s primjenom lijeka ili ne, uključivale su infekciju gornjeg respiratornog trakta i nazofaringitis.
English: If necessary, the dose of the anti-hyperglycaemic medicinal product should be adjusted during therapy with the other medicinal product and on its discontinuation.
Croatian: Ako je potrebno, dozu antihiperglikemijskih lijekova treba prilagoditi tijekom terapije s drugim lijekovima ili nakon prekida liječenja.
English: In vitro data showed that sitagliptin is not an inhibitor of CYP isoenzymes CYP3A4, 2C8, 2C9, 2D6, 1A2, 2C19 or 2B6, and is not an inducer of CYP3A4 and CYP1A2.
Croatian: In vitro podaci pokazali su da sitagliptin nije inhibitor CYP izoenzima CYP3A4, 2C8, 2C9, 2D6, 1A2, 2C19 ili 2B6 te da nije induktor CYP3A4 i CYP1A2.
English: HbA1c (%) at week 24.
Croatian: HbA1c(%) u 24. tjednu.
English: The clinical relevance of hOAT-3 in sitagliptin transport has not been established.
Croatian: Nije utvrđen klinički značaj hOAT-3 u transportu sitagliptina.
English: Transient treatment-related physical signs, some of which suggest neural toxicity, such as open-mouth breathing, salivation, white foamy emesis, ataxia, trembling, decreased activity, and/or hunched posture were observed in dogs at exposure levels approximately 23 times the clinical exposure level.
Croatian: Prolazni fizički znakovi povezani s liječenjem, od kojih neki upućuju na neurotoksičnost, poput disanja otvorenih usta, salivacije, povraćanja bijele pjene, ataksije, drhtanja, smanjene aktivnosti i/ili pogrbljenog držanja tijela opaženi su kod pasa pri razinama izloženosti otprilike 23 puta većima od razine kliničke izloženosti.
English: At the usual metformin doses and dosing schedules, steady state plasma concentrations are reached within 24-48 h and are generally less than 1 µg/mL.
Croatian: Pri uobičajenim dozama i režimu primjene metformina koncentracije u stanju dinamičke ravnoteže u plazmi postižu se unutar 24-48 h i obično su manje od 1 µg/ml.
English: In controlled clinical trials, maximum metformin plasma levels (Cmax) did not exceed 5 µg/mL, even at maximum doses.
Croatian: U kontroliranim kliničkim ispitivanjima najviše razine metformina u plazmi (Cmax) nisu čak ni pri najvišim dozama prelazile 5 µg/ml.
English: Diagnostic laboratory findings are decreased blood pH (< 7.35), increased plasma lactate levels (> 5 mmol/L) and an increased anion gap and lactate/pyruvate ratio.
Croatian: Dijagnostički laboratorijski nalazi pokazuju snižen pH krvi (<7,35), povišene razine laktata u plazmi (>5 mmol/l) i povećan anionski procjep te omjer laktata i piruvata.
English: Overall, sitagliptin improved glycaemic control when used as monotherapy or in combination treatment.
Croatian: Ukupno gledajući, sitagliptin je poboljšao regulaciju glikemije kada se uzimao kao monoterapija ili u kombiniranom liječenju.
English: It does not stimulate insulin secretion and therefore does not produce hypoglycaemia.
Croatian: Ne stimulira lučenje inzulina te stoga ne izaziva hipoglikemiju.
English: The mean glipizide dose used in the comparator group was 10 mg per day with approximately 40 % of patients requiring a glipizide dose of  5 mg/day throughout the study.
Croatian: Srednja vrijednost doze glipizida u usporednoj skupini bila je 10 mg na dan, s približno 40% bolesnika trebalo je dozu od ≤ 5 mg/dan tijekom cijeloga ispitivanja.
English: OAT3 mediated transport of sitagliptin was inhibited in vitro by probenecid, although the risk of clinically meaningful interactions is considered to be low.
Croatian: Probenecid je inhibirao transport sitagliptina in vitro posredovan OAT3, premda se rizik od klinički značajnih interakcija smatra malim.
English: Renal clearance of metformin is > 400 mL/min, indicating that metformin is eliminated by glomerular filtration and tubular secretion.
Croatian: Bubrežni klirens metformina je > 400 ml/min, što ukazuje na to da se eliminira glomerularnom filtracijom i tubularnom sekrecijom.
English: Metformin is excreted in human milk in small amounts.
Croatian: Metformin se u malim količinama izlučuje u majčino mlijeko.
English: In addition, osteoarthritis and pain in extremity were reported with frequency uncommon (> 0.5 % higher among sitagliptin users than that in the control group).
Croatian: Dodatno, prijavljeni su i osteoartritis te bol u ekstremitetima, uz kategoriju učestalosti manje često (učestalost u bolesnika liječenih sitagliptinom bila je > 0,5% veća nego u kontrolnoj skupini).
English: What Ristfor contains
Croatian: Što Ristfor sadrži
English: The following data are findings in studies performed with sitagliptin or metformin individually.
Croatian: Sljedeći se podaci odnose na rezultate ispitivanja sitagliptina ili metformina pojedinačno.
English: If pancreatitis is suspected, Ristfor and other potentially suspect medicinal products should be discontinued; if acute pancreatitis is confirmed, Ristfor should not be restarted.
Croatian: Posumnja li se na pankreatitis, mora se prekinuti primjena lijeka Ristfor i drugih lijekova za koje se sumnja da bi ga mogli izazvati; potvrdi li se akutni pankreatitis, liječenje lijekom Ristfor ne smije se ponovno započeti.
English: The dose of antihyperglycaemic therapy with Ristfor should be individualised on the basis of the patient's current regimen, effectiveness, and tolerability while not exceeding the maximum recommended daily dose of 100 mg sitagliptin.
Croatian: Dozu antihiperglikemijske terapije s lijekom Ristfor treba prilagoditi svakom pojedinom bolesniku prema postojećem režimu, učinkovitosti i podnošljivosti, ne prelazeći pritom najvišu preporučenu dnevnu dozu sitagliptina od 100 mg.
English: Stop taking Ristfor for a short time if you have a condition that may be associated with dehydration (significant loss of body fluids) such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal.
Croatian: Prestanite nakratko uzimati Ristfor ako imate stanje koje može biti povezano s dehidracijom (značajan gubitak tjelesnih tekućina) kao što je jako povraćanje, proljev, vrućica, izloženost toplini ili ako pijete manje tekućine nego obično.
English: Glucocorticoids (given by systemic and local routes) beta-2-agonists, and diuretics have intrinsic hyperglycaemic activity.
Croatian: Glukokortikoidi (dani sistemskim i lokalnim putem), beta-2 agonisti i diuretici sami po sebi imaju hiperglikemijsku aktivnost.
English: If this happens, you must stop taking Ristfor and contact a doctor or the nearest hospital immediately, as lactic acidosis may lead to coma.
Croatian: Ako Vam se to dogodi, morate prestati uzimati Ristfor i odmah se obratiti liječniku ili otići u najbližu bolnicu, jer laktacidoza može dovesti do kome.
English: Analysis in the Intention-to-Treat Population Number of patients
Croatian: Analiza u populaciji bolesnika predviđenoj za liječenje
English: Biotransformation Metformin is excreted unchanged in the urine.
Croatian: Biotransformacija Metformin se izlučuje neizmijenjen mokraćom.
English: In patients with normal renal function, metabolism, including via CYP3A4, plays only a small role in the clearance of sitagliptin.
Croatian: U bolesnika s normalnom funkcijom bubrega, metabolizam, uključujući onaj putem CYP3A4, ima tek manju ulogu u klirensu sitagliptina.
English: Stop taking Ristfor and contact a doctor or the nearest hospital immediately if you experience some of the symptoms of lactic acidosis, as this condition may lead to coma.
Croatian: Prestanite uzimati Ristfor i odmah se obratite liječniku ili otiđite u najbližu bolnicu ako osjetite neke od simptoma laktacidoze, jer to stanje može dovesti do kome.
English: Among patients taking metformin, baseline HbA1c was 8.70 % and baseline insulin dose was 37 IU/day.
Croatian: Među bolesnicima koji su uzimali metformin, početna vrijednost HbA1c bila je 8,70%, a početna doza inzulina 37 IU/dan.
English: For this reason, it is possible that potent CYP3A4 inhibitors (i.e., ketoconazole, itraconazole, ritonavir, clarithromycin) could alter the pharmacokinetics of sitagliptin in patients with severe renal impairment or ESRD.
Croatian: Stoga je moguće da potentni inhibitori CYP3A4 (tj. ketokonazol, itrakonazol, ritonavir, klaritromicin) mogu promijeniti farmakokinetiku sitagliptina u bolesnika s teškim oštećenjem funkcije bubrega ili završnom fazom bubrežne bolesti.
English: In a clinical study sitagliptin had a small effect on plasma digoxin concentrations indicating that sitagliptin may be a mild inhibitor of p-glycoprotein.
Croatian: U kliničkom ispitivanju sitagliptin je imao malen učinak na koncentracije digoksina u plazmi, što ukazuje da bi sitagliptin mogao biti blagi inhibitor p-glikoproteina.
English: The decrease in body weight with the combination of sitagliptin and metformin was similar to that observed with metformin alone or placebo; there was no change from baseline for patients on sitagliptin alone.
Croatian: Smanjenje tjelesne težine u skupini koja je uzimala kombinaciju sitagliptina i metformina bilo je slično onomu opaženom u skupini koja je uzimala samo metformin ili placebo; u bolesnika samo na sitagliptinu nije bilo promjene u odnosu na početne vrijednosti.
English: In vitro transport studies showed that sitagliptin is a substrate for p-glycoprotein and organic anion transporter-3 (OAT3).
Croatian: Istraživanja transporta in vitro pokazala su da je sitagliptin supstrat p-glikoproteina i organskog anionskog transportera- 3 (OAT3).
English: Ristfor is contraindicated in patients with GFR < 30 mL/min and should be temporarily discontinued during conditions with the potential to alter renal function (see section 4.3).
Croatian: Ristfor je kontraindiciran u bolesnika s GFR<30 ml/min i njegovu je primjenu potrebno privremeno prekinuti ako su prisutna stanja koja mijenjaju funkciju bubrega (vidjeti dio 4.3).
English: Go to the hospital if you have symptoms of lactic acidosis such as feeling cold or uncomfortable, severe nausea or vomiting, stomach ache, unexplained weight loss, muscular cramps, or rapid breathing (see section “Warnings and precautions”).
Croatian: Otiđite u bolnicu ako imate simptome laktacidoze kao što su osjećaj hladnoće i neugode, jaka mučnina ili povraćanje, bol u trbuhu, neobjašnjiv gubitak tjelesne težine, grčevi u mišićima ili ubrzano disanje (pogledajte odlomak ''Upozorenja i mjere opreza'').
English: If you take more than the prescribed dosage of this medicine, contact your doctor immediately.
Croatian: Ako uzmete više Ristfor tableta nego što ste trebali Uzmete li višu dozu ovog lijeka od propisane, odmah se javite svom liječniku.
English: • vandetanib, a medicine used to treat a specific type of thyroid cancer (medullary thyroid cancer)
Croatian: • vandetanib, lijek koji se primjenjuje za liječenje određene vrste karcinoma štitnjače
English: Reproductive toxicity studies showed a slight treatment-related increased incidence of foetal rib malformations (absent, hypoplastic and wavy ribs) in the offspring of rats at systemic exposure levels more than 29 times the human exposure levels.
Croatian: Istraživanja reproduktivne toksičnosti ukazala su na neznatno veću incidenciju prenatalnih malformacija rebara povezanih s liječenjem (nedostatak, nerazvijenost i valovita rebra) u mladunčadi štakora pri razinama sistemske izloženosti 29 puta veće od razina izloženosti u ljudi.
English: Among patients taking metformin, at Week 24, the increase in daily insulin dose was 19 IU/day in patients treated with sitagliptin and 24 IU/day in patients treated with placebo.
Croatian: Među bolesnicima koji su uzimali metformin, u 24. tjednu, porast dnevne doze inzulina bio je 19 IU/dan u bolesnika liječenih sitagliptinom, a 24 IU/dan u bolesnika koji su primali placebo.
English: Very rare: decreased vitamin B12 levels, hepatitis (a problem with your liver), hives, redness of the skin (rash) or itching
Croatian: Vrlo rijetko: snižene razine vitamina B12, hepatitis (problem s Vašom jetrom), koprivnjača, crvenilo kože (osip) ili svrbež
English: In patients taking non-pre-mixed (intermediate/long-acting) insulin, the mean daily dose was 44.3 U/day.
Croatian: U bolesnika koji su uzimali nemiješani inzulin (srednjedugog/dugog djelovanja) srednja vrijednost dnevne doze bila je 44,3 U/dan.
English: • certain medicines for the treatment of high blood pressure (ACE inhibitors and angiotensin II
Croatian: • određeni lijekovi za liječenje povišenog krvnog tlaka (ACE inhibitori i antagonisti receptora angiotenzina II)
English: Some medicinal products can adversely affect renal function, which may increase the risk of lactic acidosis, e.g. NSAIDs, including selective cyclo-oxygenase (COX) II inhibitors, ACE inhibitors, angiotensin II receptor antagonists and diuretics, especially loop diuretics.
Croatian: Neki lijekovi mogu štetno utjecati na funkciju bubrega, što može povećati rizik od laktacidoze, npr. NSAIL-ovi, uključujući selektivne inhibitore ciklooksigenaze (COX) II, ACE inhibitore, antagoniste receptora angiotenzina II i diuretike, osobito diuretike Henleove petlje.
English: Frequency categories are based on information available from metformin Summary of Product Characteristics available in the EU.
Croatian: Kategorije učestalosti temelje se na podacima dostupnima iz Sažetka opisa svojstava lijeka za metformin dostupan na tržištu Europske unije.
English: Evaluation should include serum electrolytes and ketones, blood glucose and, if indicated, blood pH, lactate, pyruvate, and metformin levels.
Croatian: Procjena treba uključivati određivanje elektrolita i ketona u serumu, glukoze u krvi te, ako je indicirano, razine pH krvi, laktata, piruvata i metformina.
English: Nervous system disorders somnolence
Croatian: Poremećaji živčanog sustava somnolencija manje često
English: In Phase I multiple-dose studies, there were no dose-related clinical adverse reactions observed with sitagliptin with doses of up to 600 mg per day for periods of up to 10 days and 400 mg per day for periods of up to 28 days.
Croatian: U ispitivanjima višekratnih doza faze I nisu zamijećene o dozi ovisne klinički značajne nuspojave sitagliptina s dozama do najviše 600 mg na dan tijekom najdulje 10 dana i u dozi od 400 mg na dan tijekom najdulje 28 dana.
English: There was no meaningful change from baseline in body weight in either group.
Croatian: Niti u jednoj skupini nije bilo značajne promjene u tjelesnoj težini u odnosu na početne vrijednosti.
English: Sitagliptin accumulates only minimally with multiple doses.
Croatian: Sitagliptin se minimalno akumulira nakon višekratnih doza.
English: Ristfor should not be used in patients with type 1 diabetes and must not be used for the treatment of diabetic ketoacidosis.
Croatian: Ristfor se ne smije primjenjivati u bolesnika s dijabetesom tipa 1 ili za liječenje dijabetičke ketoacidoze.
English: In rats, there was an increased incidence of hepatic adenomas and carcinomas at systemic exposure levels 58 times the human exposure level.
Croatian: U štakora je bila povećana incidencija adenoma i karcinoma jetre pri razinama sistemske izloženosti 58 puta većoj od razina izloženosti u ljudi.
English: Ciclosporin: A study was conducted to assess the effect of ciclosporin, a potent inhibitor of p-glycoprotein, on the pharmacokinetics of sitagliptin.
Croatian: Ciklosporin: Provedeno je ispitivanje učinka ciklosporina, potentnog inhibitora p-glikoproteina, na farmakokinetiku sitagliptina.
English: Sitagliptin was modestly removed by haemodialysis (13.5 % over a 3- to 4-hour haemodialysis session starting 4 hours post-dose).
Croatian: Sitagliptin se umjereno uklanja hemodijalizom (13,5% nakon dijalize u trajanju 3-4 sata započete 4 sata nakon doze lijeka).
English: Capsule-shaped, red film-coated tablet with “577” debossed on one side.
Croatian: Crvena filmom obložena tableta u obliku kapsule, s utisnutom oznakom "577" s jedne strane.