FrancophonIA/ELRC3.0 huggingface dataset:
English: Development of resistance to ciprofloxacin and other fluoroquinolones has been observed in staphylococci, especially methicillinresistant S. aureus, P. aeruginosa, E.coli and E. faecalis (see the sensitivity table).
Slovenian: Razvoj rezistence za ciprofloksacin in druge fluorokinolone so opazili pri stafilokokih, zlasti pri S. aureus, P. aeruginosa, E.coli in E. faecalis, rezistentnimi na meticilin (glejte tabelo občutljivosti).
English: Please inform your doctor when under treatment with Ciprofloxacin Hikma as the result of this test may be false.
Slovenian: Obvestite zdravnika, če se zdravite z zdravilom Ciprofloxacin Hikma, ker je rezultat tega preizkusa lahko napačen.
English: Important information about some of the ingredients of Ciprofloxacin Hikma If you are on a low-sodium diet, take into account that 100 ml of Ciprofloxacin Hikma contains 15.4 mmol (equivalent to 354 mg) sodium.
Slovenian: Pomembne informacije o nekaterih sestavinah zdravila Ciprofloxacin Hikma Če ste na dieti z malo natrija, morate upoštevati, da 100 ml zdravila Ciprofloxacin Hikma vsebuje 15,4 mmol (kar ustreza 354 mg) natrija.
English: This product being a solution intended for intravenous infusion, should be restricted to the treatment of complicated UTI's.
Slovenian: Ker je zdravilo raztopina za pripravo intravenske infuzije, bi njegovo uporabo morali omejiti na zdravljenje zapletenih okužb sečil.
English: If you or someone in your family suffers from this disease, you should consult your doctor.
Slovenian: Če imate to bolezen ali če jo je imel kdo v vaši družini, se morate posvetovati z zdravnikom.
English: Photosensibility:
Slovenian: Fotosenzitivnost:
English: Characteristics in patients:
Slovenian: Lastnosti pri bolnikih:
English: The CHMP has therefore recommended the granting of the Marketing Authorisation(s) and the amendment of the Summary of Product Characteristics, labelling and package leaflet of the Reference Member State.
Slovenian: CHMP je zato priporočil odobritev dovoljenj(a) za promet z zdravilom in dopolnil Povzetka glavnih značilnosti zdravila, označevanja in Navodila za uporabo za referenčno državo članico.
English: Rare: syncope (fainting), vasodilation (heat stress).
Slovenian: Redki: sinkopa (omedlevica), vazodilatacija (toplotni stres).
English: The elimination half-life of ciprofloxacin does not change with age.
Slovenian: Razpolovni čas izločanja ciprofloksacina se s starostjo ne spreminja.
English: PHARMACEUTICAL FORM AND CONTENTS Solution for infusion.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Raztopina za infundiranje
English: Ciprofloxacin Hikma cannot be mixed with solutions that are not stable at a pH of approximately 4.
Slovenian: Zdravilo Ciprofloxacin Hikma se ne sme mešati z raztopinami, ki niso stabilne pri vrednosti pH približno 4.
English: Very rarely, a partial or total rupture (in particular of the Achilles tendon) has been reported, especially in elderly patients who were previously treated systemically with glucocorticoids.
Slovenian: Zelo redko so poročali o celotni rupturi kite (predvsem ahilove kite), zlasti pri starejših bolnikih, ki so jih predhodno zdravili z glukokortikoidi.
English: Most frequent side effects affect the stomach and intestine, the nervous system and the skin and connective tissue.
Slovenian: Najpogostejši neželeni učinki prizadenejo želodec in črevo, živčevje, kožo in vezivna tkiva.
English: Due to the increased risk of local reactions, higher intravenous doses in particular should only be administered via a large vein or a central line.
Slovenian: Zaradi povečanega tveganja za pojav lokalnih reakcij je treba večje intravenske odmerke dajati z venskim ali centralnim katetrom.
English: There are insufficient data available with regard to the use of ciprofloxacin in children and adolescents.
Slovenian: Podatki o uporabi ciprofloksacina pri otrocih in mladostnikih so nezadostni.
English: However, like a number of other quinolones ciprofloxacin is phototoxic in animals in exposure values relevant to humans.
Slovenian: Vendar je tako kot veliko drugih kinolonov fototoksičen pri živalih pri izpostavljenosti, ki je primerljiva z izpostavljenostjo pri človeku.
English: In juvenile and prenatal animals exposed to quinolones effects on immature cartilage have been observed (see section 5.3).
Slovenian: Pri neodraslih in prenatalnih živalih, izpostavljenih kinolonom, so opazili učinke na hrustanec (glejte poglavje 5.3).
English: Impaired hepatic function: In case of impaired hepatic function it is not necessary to adjust the dosage.
Slovenian: Okvarjeno delovanje jeter: Pri okvarjenem delovanju jeter odmerka ni treba prilagajati.
English: Oral anticoagulants (e.g. warfarin)
Slovenian: Peroralni antikoagulansi (npr. varfarin)
English: Using other medicines If Ciprofloxacin Hikma and one of the following medicines are given at the same time, special care should be taken:
Slovenian: Uporaba drugih zdravil Če zdravilo Ciprofloxacin Hikma jemljete skupaj z enim izmed naslednjih zdravil, morate biti posebno previdni:
English: When during or after the treatment with ciprofloxacin or another fluoroquinolone severe and persistent diarrhoea occurs, pseudomembranous colitis must be taken into account (life-threatening with possibly fatal outcome).
Slovenian: Kadar se pri zdravljenju s ciprofloksacinom ali drugimi fluorokinoloni, ali po njem, pojavi huda persistentna driska, je treba upoštevati možnost, da gre za psevdomembranski kolitis (smrtno nevaren z možnim smrtnim izidom).
English: If you use one of these medicines together with ciprofloxacin you will be monitored for signs of overdose.
Slovenian: Če katero koli od teh zdravil jemljete skupaj s ciprofloksacinom, vas bodo opazovali zaradi znakov prevelikega odmerjanja.
English: • convulsions (seizures), epilepsy or another brain disease, for example decreased blood circulation in the brain, stroke or increased sensitivity to convulsions, since possible side effects of ciprofloxacin may cause damage to the brain.
Slovenian: • konvulzije (epileptične napade), epilepsijo ali drugo bolezen možganov, na primer zmanjšan pretok krvi v možganih, možgansko kap ali povečano občutljivost za epileptične napade, ker možni neželeni učinki ciprofloksacina lahko povzročijo poškodbe možganov;
English: These are set out in Annex III for Ciprofloxacin and associated names (see Annex I).
Slovenian: Ta so natančno določena v Dodatku III za zdravilo Ciprofloxacin in z njim povezana imena (oglejte si Dodatek I).
English: Ciprofloxacin Hikma is an antibiotic.
Slovenian: Zdravilo Ciprofloxacin Hikma je antibiotik.
English: • significant renal impairment.
Slovenian: • huda ledvična okvara.
English: A larger number of metabolites after oral administration indicates some degree of first-pass metabolism, mainly forming sulphociprofloxacin.
Slovenian: Večje število presnovkov po peroralni uporabi kaže na določeno stopnjo presnove prvega prehoda skozi jetra, pri čem nastaja predvsem sulfociprofloksacin.
English: The pharmacokinetics of ciprofloxacin in children with cystic fibrosis differs from that in children without cystic fibrosis, and dosing recommendations are only applicable for children with cystic fibrosis.
Slovenian: Pri otrocih s cistično fibrozo se farmakokinetika ciprofloksacina razlikuje od farmakokinetike pri otrocih brez cistične fibroze, režim odmerjanja pa velja samo za otroke s cistično fibrozo.
English: OTHER SPECIAL WARNING(S), IF NECESSARY See enclosed leaflet.
Slovenian: DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA Glejte priloženo navodilo za uporabo.
English: Very rare: erythema nodosum, erythema multiforme (minor), Stevens-Johnson syndrome, epidermal necrolysis (Lyell Syndrome), petechia.
Slovenian: Zelo redki: nodozni eritem, multiformni eritem (manjši), Stevens-Johnsonov sindrom, epidermalna nekroliza (Lyellov sindrom), petehija.
English: In very rare cases ventricular arrhythmia, QT interval prolongation and torsades de pointes have been reported.
Slovenian: V zelo redkih primerih so poročali o ventrikularni aritmiji, podaljšanju intervala QT in aritmiji "torsades de pointes".
English: Very rare: asthenia, a transient impairment of kidney function to transient renal failure, photosensitivity (see Section 4.4).
Slovenian: Zelo redki: astenija, prehodna okvara delovanja ledvic do prehodne ledvične odpovedi, fotosenzitivnost (glejte poglavje 4.4).
English: • children and growing adolescents except for the treatment of acute pulmonary exacerbations of cystic fibrosis in children aged 5 to 17 years.
Slovenian: • otrocih in odraščajočih mladostnikih, razen za zdravljenje akutnih pulmonalnih eksacerbacij cistične fibroze pri otrocih, starih od 5 do 17 let;
English: Since ciprofloxacin is associated with very rare cases of QT prolongation (see section 4.8) caution should be exercised when treating patients at risk for torsade de pointes arrhythmia.
Slovenian: Ciprofloksacin je povezan z zelo redkimi primeri podaljšanja intervala QT (glejte poglavje 4.8), zato je pri zdravljenju bolnikov s tveganjem za aritmijo "torsade de pointes", potrebna previdnost.
English: This applies to gall, kidney, gall bladder and liver tissue.
Slovenian: To velja za žolč, ledvica, žolčnik in jetrno tkivo.
English: • If you have known allergic reaction (hypersensitivity) to ciprofloxacin or any of the other ingredients of Ciprofloxacin Hikma or other medicines of the quinolone type
Slovenian: • če imate znano alergijsko reakcijo na (če ste preobčutljivi za) ciprofloksacin ali katero koli sestavino zdravila Ciprofloxacin Hikma ali druga kinolonska zdravila;
English: Adverse reactions have been reported in 5-14% of patients receiving ciprofloxacin.
Slovenian: O neželenih reakcijah so poročali pri 5-14 % bolnikov, ki so prejemali ciprofloksacin.
English: Patients with a family history of or actual defects in glucose-6-phosphate dehydrogenase activity are prone to haemolytic reactions with quinolones, and so ciprofloxacin should be used with caution in these patients.
Slovenian: Bolniki z okvaro delovanja glukoze-6-fosfat dehidrogenaze v družinski anamnezi so nagnjeni k hemolitičnim reakcijam na kinolone, zato je treba ciprofloksacin pri njih uporabljati previdno.
English: Ciprofloxacin has a rapid bactericidal effect, both in the growth phase and in the rest phase.
Slovenian: Ciprofloksacin ima hiter baktericiden učinek, v fazi razmnoževanja bakterij in tudi v fazi mirovanja.
English: administration of 200 mg the plasma concentration is still higher than the MIC values of the majority of clinically relevant pathogens (approximately 0.1 µg/ml).
Slovenian: Dvanajst ur po intravenskem dajanju odmerka 200 mg je koncentracija v plazmi še vedno večja od najmanjše zaviralne koncentracije večine klinično pomembnih povzročiteljev (približno 0,1 µg/ml).
English: In case of very severe infections the dose can be increased up to a maximum daily dose of 1200 mg (400 mg thrice daily).
Slovenian: Pri zelo hudih okužbah je lahko odmerek poveča na največji dnevni odmerek 1200 mg (400 mg trikrat na dan).
English: Signs of these reactions are: a sharp drop in blood pressure, paleness, restlessness, weak/rapid pulse, clammy skin, dizziness.
Slovenian: Znaki teh reakcij so hitro zmanjšanje krvnega tlaka, bledica, nemir, šibek/hiter srčni utrip, vlažna koža, omotica.
English: • life-threatening increase heart rate (torsade de pointes).
Slovenian: • smrtno nevarno povečanje srčnega utripa (aritmija "torsade de pointes").
English: Very rare: hepatitis, liver cell necrosis (very rarely resulting in life-threatening liver function failure).
Slovenian: Zelo redki: hepatitis, nekroza jetrnih celic (zelo redko povzroči smrtno nevarno odpoved delovanja jeter).
English: Due to the risk of arthropathy and other potentially severe toxicity in the infant, ciprofloxacin is contraindicated during lactation (see section 4.3).
Slovenian: Zaradi tveganja za artropatijo in druge hude toksične učinke na novorojenca je ciprofloksacin med dojenjem kontraindiciran (glejte poglavje 4.3).
English: Especially patients undergoing long-term treatment (e.g. in cystic fibrosis, osteomyelitis), or patients who are extremely susceptible to infections (e.g. in selective prophylaxis in certain groups of neutropenic patients, artificial ventilation) show the highest risk.
Slovenian: Največje tveganje kažejo predvsem bolniki, pri katerih je zdravljenje dolgotrajno (npr. pri cistični fibrozi in osteomielitisu), ali bolnikih, ki so zelo dovzetni za okužbe (npr. pri selektivni profilaksi pri določeni skupini nevtropeničnih bolnikov, bolnikih na umetni ventilaciji).
English: Ciprofloxacin Hikma should be administered via a short-term intravenous infusion (infusion into a vein) over 30 to 60 minutes.
Slovenian: Zdravilo Ciprofloxacin Hikma je treba dajati s kratkotrajnim intravenskim infundiranjem (infundiranjem v veno), ki traja 30 do 60 minut.
English: Within the class of quinolones cross-resistance has been observed.
Slovenian: Navzkrižno rezistenco so opazili znotraj razreda kinolonov.
English: Following concomitant administration of ciprofloxacin and cyclosporine a transient increase of the serum creatinine concentration has been observed in separate cases.
Slovenian: Po sočasni uporabi ciprofloksacina in ciklosporina so v posameznih primerih opazili prehodno povečanje koncentracije kreatinina v serumu.
English: • oral anticoagulants (used to prevent blood from clotting, e.g. warfarin).
Slovenian: • peroralni antikoagulansi (uporabljajo se za preprečevanje strjevanja krvi, npr. varfarin).
English: The interaction between theophylline and ciprofloxacin is potentially life-threatening.
Slovenian: Interakcija med teofilinom in ciprofloksacinom je lahko smrtno nevarna.
English: The reconstituted solution is clear.
Slovenian: Rekonstituirana raztopina je bistra.
English: Central nervous system:
Slovenian: Osrednje živčevje:
English: In addition the maximum daily dose for the use of ciprofloxacin should be 400 mg three times daily.
Slovenian: Poleg tega bi moral največji dnevni odmerek ciprofloksacina znašati 400 mg trikrat dnevno.
English: Ciprofloxacin, like other quinolones, may enhance the effect of coumarin derivates including warfarin.
Slovenian: Ciprofloksacin, kot drugi kinoloni, lahko okrepijo učinek derivatov kumarina, vključno z varfarinom.
English: Animal experiments have shown that ciprofloxacin passes the placenta and is excreted in breast milk.
Slovenian: Preizkusi na živalih so pokazali, da ciprofloksacin prehaja v placento in se izloča v materinem mleku.
English: Anaphylactic/anaphylactoid reactions can in very rare cases develop into life-threatening shock, sometimes even after the first administration of ciprofloxacin.
Slovenian: Anafilaktične/anafilaktoidne reakcije lahko v redkih primerih povzročijo smrtno nevarni šok, včasih že po prvem odmerku ciprofloksacina.
English: Very rare in less than 1 in 10,000 patients, including isolated reports
Slovenian: Zelo redki pri manj kot 1 bolniku od 10.000, vključno s posameznimi primeri
English: Hydrochloric acid (E 507) for pH adjustment Water for injections
Slovenian: Klorovodikova kislina (E 507) za uravnavanje pH Voda za injekcije
English: • glibenclamide (used to treat diabetes).
Slovenian: • glibenklamid (uporablja se za zdravljenje sladkorne bolezni).
English: There is a linear correlation between dose on the one hand and plasma concentration and AUC on the other.
Slovenian: Med odmerkom na eni strani in koncentracijo v plazmi ter vrednostjo AUC na drugi obstaja linearna korelacija.
English: Use only clear solutions and undamaged containers.
Slovenian: Uporabite samo bistro raztopino in nepoškodovano ovojnino.
English: In that case the ciprofloxacin therapy must immediately be discontinued and an appropriate treatment initiated.
Slovenian: V takem primeru je treba zdravljenje s ciprofloksacinom takoj prekiniti in začeti ustrezno zdravljenje.
English: • temporary pain and inflammation of the tendons, in particular of the Achilles tendon.
Slovenian: • začasna bolečina v kitah in vnetje kit, zlasti ahilove kite.
English: • certain anti-inflammatory agents (e.g. ibuprofen, naproxen, but not acetylsalicylic acid), if ciprofloxacin is given in very high doses.
Slovenian: • nekatera protivnetna zdravila (npr. ibuprofen, naproksen, vendar ne tudi acetilsalicilna kislina), če jemljete zelo velike odmerke ciprofloksacina.
English: Excipient 15.4 mmol (354 mg) sodium per 100 ml of solution for infusion For a full list of excipients, see section 6.1.
Slovenian: Pomožna snov: 15,4 mmol (354 mg) natrija na 100 ml raztopine za infundiranje Za celoten seznam pomožnih snovi glejte poglavje 6.1.
English: • caffeine (used as a stimulant), pentoxifylline (used to treat circulatory disorders in the limbs) and mexiletine (used to treat irregular heart beat).
Slovenian: • kofein (uporablja se kot poživilo), pentoksifilin (uporablja se za zdravljenje težav s krvnim obtokom v okončinah) in meksiletin (uporablja se za zdravljenje nerednega srčnega utripa).
English: Simultaneous administration of ciprofloxacin and phenytoin may result in increased or reduced serum levels of phenytoin such that monitoring of drug levels is recommended.
Slovenian: Sočasna uporaba ciprofloksacina in fenitoina lahko povzroči takšno zvišanje ali znižanje ravni fenitoina v serumu, da se priporoča spremljanje ravni zdravila v serumu.
English: Part of it is converted into desethylene-, sulpho-, oxoand formylciprofloxacin.
Slovenian: Del učinkovine se pretvori v desetilen-, sulfo-, oksoin formilciprofloksacin.
English: Ciprofloxacin is potentially neurotoxic and causes reversible defects of the testes in case of higher dosage.
Slovenian: Ciprofloksacin je potencialno nevrotoksičen, pri večjih odmerkih pa povzroča reverzibilne okvare testisov.
English: Therefore, it is recommended to avoid prolonged exposure to sunlight or UV light during treatment with ciprofloxacin.
Slovenian: Zato je treba bolnikom svetovati, naj se med zdravljenjem s ciprofloksacinom izogibajo daljšemu izpostavljanju sončni svetlobi ali UV-svetlobi.
English: Batch nr.{xxxxxx}
Slovenian: ŠTEVILKA SERIJE Serija {xxxxxx}
English: The Ciprofloxacin Hikma dosage is based on the severity and type of the infection, the sensitivity of the pathogen(s), your age, weight and kidney function.
Slovenian: Odmerjanje zdravila Ciprofloxacin Hikma temelji na stopnji in vrsti okužbe, občutljivosti povzročitelja (povzročiteljev), vaši starosti, teži in delovanju ledvic.
English: EXPIRY DATE EXP {MM/YYY} BATCH NUMBER Batch nr. {xxxxxx} CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT Presentation of 200 mg/100 ml: 100 ml OTHER
Slovenian: DATUM IZTEKA ROKA UPORABNOSTI ZDRAVILA EXP {MM/LLLL} ŠTEVILKA SERIJE Serija {xxxxxx} VSEBINA, IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ENOT Pakiranje z 200 mg/100 ml: 100 ml DRUGI PODATKI
English: - The literature provided by the applicant support a dose of 200 - 400 mg twice daily in the treatment of complicated urinary tract infections and a maximum adult daily dose of 400 mg three times daily.
Slovenian: - literature, ki jo je predložil vlagatelj in ki govori v prid odmerku 200 do 400 mg dvakrat dnevno pri zdravljenju zapletenih okužb sečil ter največjemu odmerku pri odraslih, ki znaša 400 mg trikrat dnevno,
English: Ear and labyrinth disorders: Rare: tinnitus, transient hearing loss (particularly high frequencies).
Slovenian: Ušesne bolezni, vključno z motnjami labirinta: Redki: tinitus, prehodna izguba sluha (zlasti visokih frekvenc).
English: There are limited data on the use of ciprofloxacin during pregnancy.
Slovenian: Podatki o uporabi ciprofloksacina v nosečnosti so omejeni.
English: Rare: taste loss (reduced taste), paraesthesia (peripheral paralgesia), tremor (shaking), convulsions, migraine.
Slovenian: Redki: izguba okusa (zmanjšan čut okusa), parestezija (periferna paralgezija), tremor (tresenje), konvulzije, migrena.
English: In patients with a creatinine clearance in the range 31 - 60 ml/minute/1.73 m2 or a serum creatinine concentration in the range 124 - 174 µmol/l, the maximum daily intravenous dose is 800 mg.
Slovenian: Okvarjeno delovanje ledvic: Pri bolnikih s kreatininskim očistkom od 31 do 60 ml/min/1,73 m2 ali koncentracijo kreatinina v serumu od 124 do 174 µmol/l je največji dnevni intravenski odmerek 800 mg.
English: According to EUCAST the following breakpoints for aerobic bacteria have been defined for ciprofloxacin:
Slovenian: Po merilih odbora EUCAST so za aerobne bakterije opredelili naslednje mejne vrednosti za ciprofloksacin:
English: After oral administration 45% is excreted unchanged in the urine and 25% is excreted in the faeces.
Slovenian: Po peroralni uporabi se 45 % izloči nespremenjenega v urinu, 25 % pa v blatu.
English: If there is any indication of tendinitis (e.g. painful swelling) the administration of ciprofloxacin or other fluoroquinolones must immediately be discontinued, the affected extremity should not be strained and a physician must be consulted.
Slovenian: Če se pojavijo kakršni koli znaki tendinitisa (npr. boleča oteklina), je treba zdravljenje s ciprofloksacinom ali drugimi fluorokinoloni takoj ustaviti, prenehati je treba telesno dejavnost in se posvetovati z zdravnikom.
English: Side effects have been reported in 5-14% of patients receiving ciprofloxacin.
Slovenian: O neželenih učinkih so poročali pri 5-14 odstotkih bolnikov, ki so prejemali ciprofloksacin.
English: Mutagenicity of ciprofloxacin has not been indicated in mutagenicity studies.
Slovenian: Mutagenosti ciprofloksacina v študijah mutagenosti niso pokazali.
English: If such reactions occur, treatment with ciprofloxacin must be discontinued immediately and the treating physician informed.
Slovenian: Če se pojavijo take reakcije, je treba zdravljenje s ciprofloksacinom takoj prekiniti in obvestiti lečečega zdravnika.
English: • Ciprofloxacin may inhibit the excretion of methotrexate via the kidney, causing an increased methotrexate level in the blood.
Slovenian: • ciprofloksacin lahko zavre izločanje metotreksata skozi ledvica, zaradi česar se lahko raven metotreksata v krvi poveča;
English: Ciprofloxacin is effective in vitro against a large number of Gram-negative aerobic bacteria including P. aeruginosa.
Slovenian: Ciprofloksacin je in vitro učinkovit proti velikem številu gramnegativnih aerobnih bakterij, vključno s P. aeruginosa.
English: Hypersensitivity reactions and allergic reactions occurred in some cases after the first administration of ciprofloxacin.
Slovenian: Preobčutljivostne in alergijske reakcije so se v nekaterih primerih pojavile že po prvem odmerku ciprofloksacina.
English: However, since decreased clearance of diazepam, with a prolonged half-life have been reported during co-administration of ciprofloxacin and diazepam, and in very rare cases with midazolam, careful monitoring of benzodiazepine therapy is recommended.
Slovenian: Vendar so pri sočasni uporabi ciprofloksacina in diazepama ter v zelo redkih primerih midazolama poročali o zmanjšanem očistku in podaljšanem razpolovnem času diazepama, zato se priporoča pozorno spremljanje zdravljenja z benzodiazepinom.
English: Like all medicines, Ciprofloxacin Hikma can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo Ciprofloxacin Hikma neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Resistance to ciprofloxacin develops in stages through genomic mutations (multiple-step type).
Slovenian: Rezistenca za ciprofloksacin se razvija postopno skozi genomske mutacije (po korakih).
English: Therefore, patients receiving methotrexate therapy should be carefully monitored when concomitant ciprofloxacin therapy is indicated.
Slovenian: Zato je treba bolnike, ki prejemajo metotreksat, pri sočasnem zdravljenju s ciprofloksacinom pozorno spremljati.
English: You must not breast-feed your child during treatment with ciprofloxacin, due to the risk of malformation of joint cartilage and other harmful effects in the breast-fed infant.
Slovenian: Med zdravljenjem s ciprofloksacinom ne smete dojiti, zaradi tveganja za deformacije hrustanca v sklepih dojenčka ali druge škodljive učinke.