FrancophonIA/ELRC3.0 huggingface dataset:
English: In a drug interaction study of intranasal fluticasone furoate with the potent CYP3A4 inhibitor ketoconazole there were more subjects with measurable fluticasone furoate concentrations in the ketoconazole group (6 of the 20 subjects) compared to placebo (1 out of 20 subjects).
Croatian: U ispitivanju interakcije intranazalno primijenjenog flutikazonfuroata s potentnim inhibitorom CYP3A4 ketokonazolom, u skupini na ketokonazolu (6 od 20 ispitanika) je bilo više ispitanika s mjerljivim koncentracijama flutikazonfuroata u usporedbi s placebom (1 od 20 ispitanika).
English: A
Croatian: I
English: Children 6 to 11 years
Croatian: Djeca od 6 do 11 godina starosti
English: Avamys nasal spray is used to treat symptoms of allergic rhinitis including stuffy, runny or itchy nose, sneezing and watery, itchy or red eyes, in adults and children aged 6 years and over.
Croatian: Avamys sprej za nos koristi se u liječenju simptoma alergijskog rinitisa, uključujući začepljenje, curenje ili svrbež nosa, kihanje i suzne oči s osjećajem svrbeža i crvenilom, kod odraslih i djece od 6 i više godina starosti.
English: Hypersensitivity reactions including anaphylaxis, angioedema, rash, and urticaria.
Croatian: Rijetko reakcije preosjetljivosti, uključujući anafilaksiju, angioedem, osip i urtikariju
English: The primary outcomes [time to increase in posterior subcapsular opacity (0.3 from baseline in Lens Opacities Classification System, Version III (LOCS III grade)) and time to increase in intraocular pressure (IOP; 7 mmHg from baseline)] were not statistically significant between the two groups.
Croatian: Nije bilo statistički značajnih razlika u primarnim ishodima [vrijeme povećanja stražnjeg subkapsularnog zamućenja (0,3 od početne vrijednosti prema Lens Opacities Classification System, verzija III (LOCS III stupanj)) i vrijeme povećanja intraokularnog tlaka (IOT; 7 mmHg od početne vrijednosti)] između dvije skupine.
English: Fluticasone furoate 110 micrograms once daily was not associated with hypothalamic-pituitary-adrenal (HPA) axis suppression in adult, adolescent or paediatric subjects.
Croatian: Flutikazonfuroat u dozi od 110 mikrograma jednom na dan nije bio povezan sa supresijom osi hipotalamus-hipofiza-nadbubrežna žlijezda (HPA) kod odraslih, adolescenata i djece.
English: This is not likely to be relevant for humans given recommended nasal doses which results in minimal systemic exposure (see section 5.2).
Croatian: Međutim, to se ne smatra relevantnim kod ljudi pri preporučenim nazalno primijenjenim dozama koje imaju za posljedicu minimalnu sistemsku izloženost (vidjeti dio 5.2).
English: The intranasal dosing of 110 micrograms once daily does not typically result in measurable plasma concentrations (<10 pg/ml).
Croatian: mikrograma jednom na dan obično ne rezultira mjerljivim koncentracijama u plazmi (<10 pg/ml).
English: Driving and using machines Avamys is unlikely to affect your ability to drive and use machines.
Croatian: Upravljanje vozilima i strojevima Smatra se da Avamys ne utječe na sposobnost upravljanja vozilima i strojevima.
English: Be careful not to get any spray into your eyes.
Croatian: Ne smije doći u doticaj s očima.
English: In a two-year study designed to assess the ocular safety of fluticasone furoate (110 micrograms once daily intranasal spray), adults and adolescents with perennial allergic rhinitis received either fluticasone furoate (n=367) or placebo (n=181).
Croatian: U dvogodišnjem ispitivanju dizajniranom da procijeni sigurnost očiju pri uporabi flutikazonfuroata (u dozi od 110 mg jednom dnevno u obliku spreja za nos), odrasli i djeca s višegodišnjim alergijskim rinitisom primali su ili flutikazonfuroat (n=367) ili placebo (n=181).
English: It is best to store your Avamys nasal spray upright.
Croatian: Najbolje je da Avamys sprej za nos čuvate u uspravnom položaju.
English: The values are similar to those seen in adults (12+) where median concentrations in those subjects with quantifiable levels were 15.4 pg/ml and 21.8 pg/ml at 55 micrograms and 110 micrograms, respectively.
Croatian: Vrijednosti su slične onima primijećenima kod odraslih osoba (12 i više godina), gdje su medijani koncentracije kod ispitanika s mjerljivim vrijednostima bile 15,4 pg/ml pri 55 mikrograma i 21,8 pg/ml pri 110 mikrograma.
English: A randomised, double-blind, parallel-group, multicenter, one-year placebo-controlled clinical growth study evaluated the effect of fluticasone furoate nasal spray 110 micrograms daily on growth velocity in 474 prepubescent children (5 to 7.5 years of age for girls and 5 to 8.5 years of age for boys) with stadiometry.
Croatian: Randomizirano, dvostruko slijepo, multicentrično, placebom kontrolirano jednogodišnje ispitivanje rasta s paralelnim skupinama procjenjivalo je visinomjerom učinak flutikazonfuroata od 110 mikrograma u obliku spreja za nos na brzinu rasta u 474 djece u pretpubertetu (djevojčice u dobi od 5 do 7,5 godina te dječaci u dobi od 5 do 8,5 godina).
English: If there is any reason to believe that adrenal function is impaired, care must be taken when transferring patients from systemic steroid treatment to fluticasone furoate.
Croatian: Ako postoji i najmanji razlog sumnje na oštećenje adrenalne funkcije, nužan je oprez prilikom prijelaza s liječenja sistemskim steroidima na flutikazonfuroat.
English: Following repeat dosing of orally inhaled fluticasone furoate/vilanterol for 7 days, there was an increase in fluticasone furoate systemic exposure (on average two-fold as measured by AUC(0-24)) in subjects with moderate or severe hepatic impairment (Child-Pugh B or C) compared with healthy subjects.
Croatian: Nakon ponavljanog doziranja oralno inhalirane kombinacije flutikazonfuroat/vilanterol tijekom 7 dana, došlo je do povećanja sistemske izloženosti flutikazonfuroatu (u prosjeku dvostruko prema mjerenju AUC(0-24)) u ispitanika s umjerenim ili teškim oštećenjem jetre (Child-Pugh B ili C) u usporedbi sa zdravim ispitanicima.
English: Preparing the nasal spray for use
Croatian: Priprema spreja za nos za uporabu
English: How to use the nasal spray
Croatian: Kako koristiti sprej za nos
English: Mechanism of action: Pharmacotherapeutic group: Nasal preparations, corticosteroids.
Croatian: Farmakoterapijska skupina: Nazalni pripravci kortikosteroida.
English: However the dose of intranasal fluticasone furoate should be reduced to the lowest dose at which effective control of the symptoms of rhinitis is maintained.
Croatian: Međutim, potrebno je smanjiti intranazalnu dozu flutikazonfuroata na najnižu dozu kojom se učinkovito održava kontrola simptoma rinitisa.
English: The other ingredients are glucose anhydrous, dispersible cellulose, polysorbate 80, benzalkonium chloride, disodium edetate, purified water (see section 2).
Croatian: Drugi sastojci su bezvodna glukoza, disperzibilna celuloza, polisorbat 80, benzalkonijev klorid, dinatrijev edetat i pročišćena voda (vidjeti dio 2).
English: Post-hoc analysis over 6 and 12 weeks in the same study, as well as 6-week HPA axis safety study, supported the efficacy of fluticasone furoate nasal spray 110 micrograms once daily.
Croatian: Post-hoc analiza nakon 6 i 12 tjedana, u istom ispitivanju kao i 6-tjedna ispitivanja sigurnosti HPA osi, išli su u prilog djelotvornosti spreja za nos koji sadržava flutikazonfuroat primijenjen u dozi od 110 mikrograma jednom na dan.
English: Paediatric exposure to fluticasone furoate in safety and efficacy studies in seasonal and perennial allergic rhinitis included 243 patients 12 to <18 years, 790 patients 6 to <12 years and 241 patients 2 to <6 years.
Croatian: U ispitivanjima sigurnosti i djelotvornosti u pedijatrijskih bolesnika sa sezonskim i cjelogodišnjim alergijskim rinitisom flutikazonfuroatu je bilo izloženo 243 bolesnika u dobi od 12 do < 18 godina, 790 bolesnika u dobi od 6 do < 12 godina te 241 bolesnik u dobi od 2 do < 6 godina.
English: Compared with placebo, fluticasone furoate nasal spray 110 micrograms once daily significantly improved nasal symptoms (comprising rhinorrhoea, nasal congestion, sneezing and nasal itching) and ocular symptoms (comprising itching/burning, tearing/watering and redness of the eyes) in all 4 studies.
Croatian: U usporedbi s placebom, sprej za nos koji sadržava flutikazonfuroat, primijenjen u dozi od 110 mikrograma jednom na dan, značajno smanjuje nazalne simptome (koji uključuju curenje iz nosa, kongestiju nosa, kihanje i svrbež nosa) te očne simptome (koji uključuju svrbež/peckanje, suzenje i crvenilo očiju) u sva 4 ispitivanja.
English: study of a single 400 microgram dose of orally inhaled fluticasone furoate in patients with moderate hepatic impairment (Child-Pugh B) resulted in increased Cmax (42 %) and AUC(0-∞) (172 %) and a modest (on average 23 %) decrease in cortisol levels in patients compared to healthy subjects.
Croatian: Ispitivanje jednokratne doze od 400 mikrograma oralno inhaliranog flutikazonfuroata kod bolesnika s umjerenim oštećenjem jetre (Child-Pugh B) rezultiralo je povišenim Cmax (42%) i AUC (0∞) (172%) te umjerenim (u prosjeku 23%) smanjenjem vrijednosti kortizola u bolesnika u usporedbi sa zdravim ispitanicima.
English: Systemic effects of nasal corticosteroid may occur, particularly at high doses prescribed for prolonged periods.
Croatian: Može doći do pojave sistemskih učinaka nazalno primijenjenih kortikosteroida, osobito pri visokim dozama propisanima u duljem razdoblju.
English: Fertility There are no fertility data in humans.
Croatian: Nema podataka o utjecaju na plodnost u ljudi.
English: A 6-week study that assessed the effect of fluticasone furoate nasal spray 110 micrograms once daily on adrenal function in children aged 2 to 11 years showed that there was no significant effect on 24-hour serum cortisol profiles, compared with placebo.
Croatian: 6-tjedno ispitivanje, koje je ocjenjivalo učinak spreja za nos koji sadržava flutikazonfuroat primijenjen u dozi od 110 mikrograma jednom na dan, na adrenalnu funkciju kod djece u dobi između 2 i 11 godina nije pokazalo značajan učinak na 24-satnu koncentraciju serumskog kortizola u usporedbi s placebom.
English: Renal Impairment No dose adjustment is required in this population (see section 5.2).
Croatian: Nema potrebe za prilagođavanjem doze u toj populaciji (vidjeti dio 5.2).
English: Also contains: Glucose anhydrous, dispersible cellulose, polysorbate 80, benzalkonium chloride, disodium edetate, purified water.
Croatian: Također sadrži: bezvodnu glukozu, disperzibilnu celulozu, polisorbat 80, benzalkonijev klorid, dinatrijev edetat i pročišćenu vodu.
English: The medicine is a white nasal spray suspension contained in an amber glass bottle, fitted with a pump.
Croatian: Lijek je sprej za nos u obliku suspenzije bijele boje u smeđoj staklenoj bočici s pumpicom.
English: The bottle is in an off-white plastic casing with a light blue cap and side-actuated lever.
Croatian: Bočica je u gotovo bijelom plastičnom spremniku sa svijetloplavim zatvaračem i bočnom tipkom za aktivaciju.
English: Uncommon side effects (may affect up to 1 in 100 people) • Pain, burning, irritation, soreness or dryness in the inside of the nose.
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na 100 osoba) Bol, peckanje, iritacija, osjetljivost i suhoća unutrašnjosti nosa.
English: Further, there were no treatment-related increases in the incidence of tumours in two year inhalation studies in rats and mice.
Croatian: Nadalje, u dvogodišnjem inhalacijskom ispitivanju na štakorima i miševima nije došlo do povišenja incidencije tumora povezanih s liječenjem.
English: If you have any further questions on the use of this medicine, or if you have any discomfort using the nasal spray ask your doctor or pharmacist or nurse.
Croatian: U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka ili ako imate bilo kakve smetnje kod primjene spreja za nos, obratite se svom liječniku, ljekarniku ili medicinskoj sestri.
English: 4 Press the button firmly all the way in. Do this at least 6 times until it releases a fine mist of spray into the air - see picture f.
Croatian: Učinite to bar 6 puta dok se ne otpusti fina maglica spreja u zrak - pogledajte sliku f.
English: When the cap is in place the mistrelease button cannot be pressed accidentally.
Croatian: Kada je zatvarač na svom mjestu, ne može slučajno doći do pritiskanja tipke za ispuštanje maglice.
English: Growth retardation has been reported in children receiving nasal corticosteroids at licensed doses.
Croatian: Prijavljeno je zaostajanje u rastu djece koja su primala nazalne kortikosteroide pri dozvoljenim dozama.
English: A reduction in growth velocity has been observed in children treated with fluticasone furoate 110 micrograms daily for one year (see section 4.8 and section 5.1).
Croatian: U djece liječene flutikazonfuroatom od 110 mg na dan tijekom jedne godine uočeno je zaostajanje u rastu ( vidjeti dio 4.8 i dio 5.1).
English: There were over 2700 patients treated with fluticasone furoate in safety and efficacy studies for seasonal and perennial allergic rhinitis.
Croatian: Više od 2700 bolesnika sa sezonskim i cjelogodišnjim alergijskim rinitisom liječeno je flutikazonfuroatom u ispitivanjima sigurnosti i djelotvornosti.
English: • The usual starting dose is 2 sprays in each nostril once every day.
Croatian: Uobičajena početna doza je 2 potiska u svaku nosnicu jednom na dan.
English: EXPIn-use shelf life: 2 months
Croatian: EXP: Rok valjanosti nakon otvaranja: 2 mjeseca
English: 3 Never use a pin or anything sharp on the nozzle.
Croatian: 3 Nikad ne koristite iglu niti išta oštro da očistite raspršivač.
English: Elimination was primarily via the faecal route following oral and intravenous administration indicative of excretion of fluticasone furoate and its metabolites via the bile.
Croatian: Nakon peroralne i intravenske primjene, eliminacija se primarno odvija putem fecesa što ukazuje na ekskreciju flutikazonfuroata i njegovih metabolita putem žuči.
English: Fluticasone furoate nasal spray significantly improved the patients' perception of overall response to therapy, and the patients' disease-related quality of life (Rhinoconjunctivitis Quality of Life Questionnaire - RQLQ), in all 4 studies.
Croatian: Sprej za nos koji sadržava flutikazonfuroat značajno poboljšava bolesnikovu percepciju ukupnog odgovora na terapiju te bolesnikovu kvalitetu života povezanu s bolešću (Upitnik o kvaliteti života povezanoj s rinokonjuktivitisom - RQLQ; engl.
English: In addition, consideration should be given to referring the patient to a paediatric specialist (see section
Croatian: Nadalje, potrebno je razmotriti upućivanje bolesnika specijalisti pedijatru (vidjeti dio 5.1).
English: 3 Hold the nasal spray upright, then tilt and point the nozzle away from you.
Croatian: 3 Držite sprej za nos uspravno, potom ga nagnite i usmjerite raspršivač od Vas.
English: At 110 micrograms, median concentrations in those subjects with quantifiable levels were 14.3 pg/ml and 14.4 pg/ml for 2-5 yrs and 6-11 yrs, respectively.
Croatian: Pri 110 mikrograma, medijan koncentracija kod ispitanika s mjerljivim vrijednostima bile su 14,3 pg/ml u djece u dobi od 2 do 5 godina i 14,4 pg/ml u djece u dobi od 6 do 11 godina.
English: • Use once a day
Croatian: • prije nego ga prvi put koristite
English: Increases in posterior subscapsular opacity (0.3 from baseline) were more frequent in subjects treated with fluticasone furoate 110 micrograms [14 (4%)] versus placebo [4 (2%)] and were transient in nature for ten subjects in the fluticasone furoate group and two subjects in the placebo group.
Croatian: Povećanje stražnje subkapsularne zamućenosti (≥0,3 od početne vrijednosti) bilo je češće u ispitanika liječenih flutikazonfuroatom 110 mikrograma [14 (4%)] u odnosu na placebo [4 (2%)] i bilo je prolazne naravi za 10 ispitanika iz skupine liječene flutikazonfuroatom i 2 ispitanika iz skupine liječene placebom.
English:  See Step-by-step guide to using the nasal spray, after Section 6.
Croatian: Pogledajte Korak po korak vodič za korištenje spreja za nos na kraju dijela 6.
English: How to store Avamys
Croatian: Kako primjenjivati Avamys
English: Growth retardation **In a one-year clinical study assessing growth in pre-pubescent children receiving 110 micrograms of fluticasone furoate once daily, an average treatment difference of -0.27 cm per year in growth velocity was observed compared to placebo (see Clinical efficacy and safety).
Croatian: **U jednogodišnjem kliničkom ispitivanju, u kojem se ocjenjivao rast djece u pretpubertetu liječene flutikazonfuroatom u dozi od 110 mikrograma jedanput na dan, prosječna razlika u brzini rasta djece liječene flutikazonfuroatom iznosila je -0,27 cm na godinu u usporedbi s djecom koja su primala placebo (vidjeti dio 'Klinička djelotvornost i sigurnost').
English: Caution is recommended when co-administering fluticasone furoate with potent CYP3A inhibitors including cobicistat-containing products as an increase in the risk of systemic side effects is expected.
Croatian: Potreban je oprez prilikom istovremene primjene flutikazonfuroata s potentnim inhibitorima CYP3A4, uključujući lijekove koji sadrže kobicistat s obzirom da se očekuje povećanje rizika od sistemskih nuspojava.
English: Perennial Allergic Rhinitis in adults and adolescents:
Croatian: Cjelogodišnji alergijski rinitis kod odraslih i adolescenata:
English: STEP-BY-STEP GUIDE TO USING THE NASAL SPRAY
Croatian: KORAK PO KORAK VODIČ ZA UPORABU SPREJA ZA NOS
English: Patients not adequately responding to one spray actuation in each nostril once daily (total daily dose, 55 micrograms) may use two spray actuations in each nostril once daily (total daily dose, 110 micrograms).
Croatian: Bolesnici kod kojih ne dođe do odgovarajuće reakcije na jedan potisak spreja u svaku nosnicu jednom na dan (ukupna dnevna doza od 55 mikrograma) mogu primjenjivati dva potiska spreja u svaku nosnicu jednom na dan (ukupna dnevna doza od 110 mikrograma).
English: Breast-feeding It is unknown whether nasal administered fluticasone furoate is excreted in human breast milk.
Croatian: Nije poznato izlučuje li se kod ljudi nazalno primijenjen flutikazonfuroat u majčino mlijeko.
English: Do not use Avamys if you are breast feeding unless your doctor or pharmacist tells you to.
Croatian: Ne primjenjujte Avamys ako dojite, osim na preporuku liječnika ili ljekarnika.
English: It will damage the nasal spray
Croatian: To će oštetiti sprej za nos.
English: Once adequate control of symptoms is achieved, dose reduction to one spray actuation in each nostril once daily (total daily dose, 55 micrograms) is recommended.
Croatian: Kada se postigne odgovarajuća kontrola simptoma, preporučuje se smanjenje doze na jedan potisak spreja u svaku nosnicu jednom na dan (ukupna dnevna doza od 55 mikrograma).
English: In children this side effect can cause them to grow more slowly than others.
Croatian: Kod djece to može dovesti do usporenijeg rasta u odnosu na vršnjake.
English: Hepatic Impairment No dose adjustment is required in patients with hepatic impairment (see section 5.2).
Croatian: Nema potrebe za prilagođavanjem doze u bolesnika s oštećenjem jetre (vidjeti dio 5.2).
English: • The usual starting dose is 1 spray in each nostril once a day.
Croatian: Uobičajena početna doza je 1 potisak u svaku nosnicu jednom na dan.
English: Median fluticasone furoate concentrations in those subjects with quantifiable levels at 55 micrograms were 18.4 pg/ml and 18.9 pg/ml for 2-5 yrs and 6-11 yrs, respectively.
Croatian: Medijan koncentracija flutikazonfuroata kod ispitanika s mjerljivim vrijednostima pri 55 mikrograma bile su 18,4 pg/ml u djece u dobi od 2 do 5 godina i 18,9 pg/ml u djece u dobi od 6 do 11 godina.
English: The intranasal device should be shaken before use.
Croatian: Prije uporabe potrebno je protresti napravu za intranazalnu primjenu.
English: In seasonal allergic rhinitis, fluticasone furoate nasal spray 110 micrograms once daily was effective but no significant differences were observed between fluticasone furoate nasal spray 55 micrograms once daily and placebo on any endpoint.
Croatian: U sezonskom alergijskom rinitisu sprej za nos koji sadržava flutikazonfuroat, primijenjen u dozi od 110 mikrograma jednom dnevno, bio je učinkovit, ali nisu primijećene značajne razlike između spreja za nos koji sadržava flutikazonfuroat, primijenjen u dozi od 55 mikrograma jednom na dan, i placeba niti u jednom ishodu.
English: It is recommended that the growth of children receiving prolonged treatment with nasal corticosteroids is regularly monitored.
Croatian: Preporučuje se redovito praćenje rasta djece koja su na produljenom liječenju nazalnim kortikosteroidima.
English: Growth retardation has been reported in children receiving nasal corticosteroids.
Croatian: Prijavljen je poremećaj u rastu kod djece koja su primala nazalne kortikosteroide.
English: In perennial allergic rhinitis, fluticasone furoate nasal spray 55 micrograms once daily exhibited a more consistent efficacy profile than fluticasone furoate nasal spray 110 micrograms once daily over 4 weeks' treatment.
Croatian: U cjelogodišnjem alergijskom rinitisu, sprej za nos koji sadržava flutikazonfuroat primijenjen u dozi od 55 mikrograma jednom na dan pokazao je konzistentniji profil djelotvornosti nego jednokratna dnevna doza od 110 mikrograma flutikazonfuroata tijekom 4-tjednog liječenja.
English: Fluticasone furoate nasal spray 110 micrograms once daily significantly improved nasal symptoms as well as patients' perception of overall response to therapy compared to placebo in three studies.
Croatian: Sprej za nos koji sadržava flutikazonfuroat, primijenjen u dozi od 110 mikrograma jednom na dan, značajno je smanjio nazalne simptome kao i poboljšao bolesnikovu percepciju ukupnog odgovora na terapiju u usporedbi s placebom u tri ispitivanja.
English: Safety and efficacy studies were performed in a total of 271 patients from 2 to 5 years of age in both seasonal and perennial allergic rhinitis, of whom 176 were exposed to fluticasone furoate.
Croatian: Sezonski i cjelogodišnji alergijski rinitis kod djece (mlađe od 6 godina): Ispitivanja sigurnosti i djelotvornosti izvođena su na ukupno 271 bolesnika u dobi od 2 do 5 godina i u sezonskom i u cjelogodišnjem alergijskom rinitisu, od čega je 176 ispitanika bilo izloženo flutikazonfuroatu.
English: The recommended starting dose is two spray actuations (27.5 micrograms of fluticasone furoate per spray actuation) in each nostril once daily (total daily dose, 110 micrograms).
Croatian: Preporučena početna doza je dva potiska spreja (27,5 mikrograma flutikazonfuroata po svakom potisku spreja) u svaku nosnicu jednom na dan (ukupna dnevna doza od 110 mikrograma).
English: Children and adolescents Do not use in children under 6 years old.
Croatian: Ne primjenjivati u djece ispod 6 godina starosti.
English: Fluticasone furoate nasal spray 110 micrograms once daily significantly improved ocular symptoms as well as improving patients' disease-related quality of life (RQLQ) compared to placebo in one study.
Croatian: Sprej za nos koji sadrži flutikazonfuroat, primijenjen u dozi od 110 mikrograma jednom na dan, značajno je smanjio očne simptome te poboljšao bolesnikovu kvalitetu života povezanu s bolešću (RQLQ) u usporedbi s placebom u jednom ispitivanju.
English: AVAMYS 27.5 micrograms/spray, nasal spray suspension
Croatian: AVAMYS 27,5 mikrograma/potisak, sprej za nos, suspenzija
English: • Once symptoms are controlled you may be able to decrease your dose to 1 spray in each nostril,
Croatian: Nakon postizanja kontrole simptoma, doza se može smanjiti na 1 potisak u svaku nosnicu jednom na dan.
English: 2 Remove the cap by squeezing firmly on the sides of the cap with your thumb and forefinger- see picture e.
Croatian: 2 Skinite zatvarač na način da čvrsto pritisnete s obje strane zatvarača palcem i kažiprstompogledajte sliku e.
English: The recommended starting dose is one spray actuation (27.5 micrograms of fluticasone furoate per spray actuation) in each nostril once daily (total daily dose, 55 micrograms).
Croatian: Preporučena početna doza je jedan potisak spreja (27,5 mikrograma flutikazonfuroata po svakom potisku spreja) u svaku nosnicu jednom na dan (ukupna dnevna doza 55 mikrograma).
English: What you need to know before you use Avamys
Croatian: Što morate znati prije nego počnete primjenjivati Avamys Nemojte primjenjivati Avamys: