FrancophonIA/ELRC3.0 huggingface dataset:
English: There are no prospectively randomised comparisons of the two recommended mobilisation methods (filgrastim alone, or in combination with myelosuppressive chemotherapy) within the same patient population.
Slovenian: Prospektivno randomiziranih primerjav dveh priporočenih metod izplavljanja pri isti populaciji bolnikov ni (samo filgrastim ali v kombinaciji z mielosupresivno kemoterapijo).
English: Myelodysplastic syndrome or Chronic myeloid leukemia The safety and efficacy of filgrastim administration in patients with myelodysplastic syndrome or chronic myelogenous leukaemia have not been established.
Slovenian: Mielodisplastični sindrom ali kronična mieloična levkemija Varnost in učinkovitost filgrastima pri bolnikih z mielodisplastičnim sindromom ali kronično mielogeno levkemijo nista bili dokazani.
English: The needle cover of the pre-filled syringe contains dry natural rubber (latex, see section 4.4).
Slovenian: Pokrov igle napolnjene injekcijske brizge lahko vsebuje suho naravno gumo (lateks, glejte poglavje 4.4).
English: Infections and malignancies causing myelosuppression Neutropenia may be due to bone marrow infiltrating opportunistic infections such as Mycobacterium avium complex or malignancies such as lymphoma.
Slovenian: Okužbe in maligna obolenja, ki povzročajo mielosupresijo Nevtropenija je lahko posledica infiltracije kostnega mozga z oportunističnimi okužbami, npr. kompleksom Mycobacterium avium ali malignimi obolenji, kot je limfom.
English: Grastofil works by stimulating the bone marrow to produce more white blood cells.
Slovenian: Zdravilo Grastofil deluje tako, da spodbuja kostni mozeg k proizvajanju več belih krvnih celic.
English: Grastofil may be given as a 30 minute or 24 hour intravenous infusion or given by continuous 24 hour subcutaneous infusion.
Slovenian: Grastofil se lahko daje v obliki 30-minutne ali 24-urne intravenske infuzije ali v obliki stalne 24-urne subkutane infuzije.
English: Platelet counts should be monitored closely, especially during the first few weeks of filgrastim therapy.
Slovenian: Zato je treba natančno spremljati število trombocitov, zlasti v prvih nekaj tednih zdravljenja s filgrastimom.
English: Grastofil can be removed from the refrigerator and left at room temperature (not above 25℃) for a single period of up to 15 days that ends within the labelled expiry date.
Slovenian: Zdravilo Grastofil lahko vzamete iz hladilnika in ga pustite pri sobni temperaturi (do 25 °C) enkrat za največ 15 dni znotraj označenega roka uporabnosti.
English: In patients undergoing a stem cell or bone marrow transplant, Graft versus host disease (GvHD) may occur- this is a reaction of the donor cells against the patient receiving the transplant; signs and symptoms include rash on the palms of your hands or soles of your feet and ulcer and sores in your mouth, gut, liver, skin, or your eyes, lungs, vagina and joints.
Slovenian: Pri bolnikih, pri katerih poteka presaditev matičnih celic ali kostnega mozga, se lahko pojavi bolezen presadka proti gostitelju (GvHD - Graft versus host disease); to je reakcija celic darovalca proti bolniku, ki prejme presadek; znaki in simptomi vključujejo izpuščaj na dlaneh ali podplatih ter razjede in vnetja v ustih, na črevesju, jetrih, koži ali očeh, pljučih, nožnici in sklepih.
English: Filgrastim should not be administered to patients with severe congenital neutropenia who develop leukaemia or have evidence of leukaemic evolution.
Slovenian: Filgrastima se ne sme uporabljati pri bolnikih s hudo prirojeno nevtropenijo, pri katerih se razvije levkemija ali pri katerih obstajajo dokazi levkemičnega razvoja.
English: If you use more Grastofil than you should, contact your doctor or pharmacist as soon as possible.
Slovenian: Če ste uporabili večji odmerek zdravila Grastofil, kot bi smeli Če ste uporabili več zdravila Grastofil, kot bi smeli, se čimprej posvetujte z zdravnikom ali farmacevtom.
English: Patients who develop symptoms of capillary leak syndrome should be closely monitored and receive standard symptomatic treatment, which may include a need for intensive care (see section 4.8).
Slovenian: Prejeti morajo standardno simptomatsko zdravljenje, v okviru katerega je lahko potrebna tudi intenzivna nega (glejte poglavje 4.8).
English: Grastofil 30 MU/0.5 mL
Slovenian: Grastofil 30 M e./0,5 ml
English: Take special care with other medicines that stimulate white blood cells Grastofil is one of a group of medicines that stimulate the production of white blood cells.
Slovenian: Pri drugih zdravilih, ki spodbujajo bele krvne celice, bodite posebno previdni Zdravilo Grastofil je ena skupina zdravil, ki spodbujajo nastajanje belih krvnih celic.
English: In clinical studies and the post-marketing setting pulmonary adverse reactions including interstitial lung disease, pulmonary oedema, and lung infiltration have been reported in some cases with an outcome of respiratory failure or acute respiratory distress syndrome (ARDS), which may be fatal (see section 4.4).
Slovenian: V kliničnih študijah in v obdobju trženja so neželeni učinki na pljučih vključevali intersticijsko pljučno bolezen, pljučni edem in pljučne infiltrate in so imeli v nekaterih primerih za posledico dihalno odpoved ali sindrom akutne dihalne stiske (ARDS), ki sta lahko usodna (glejte poglavje 4.4).
English: There have been reports of GvHD and fatalities in patients receiving G-CSF after allogeneic bone marrow transplantation (see sections 4.4 and 5.1).
Slovenian: Poročali so o GvHD in o smrtnih primerih pri bolnikih, ki so G-CSF prejemali po alogenski presaditvi kostnega mozga (glejte poglavji 4.4 in 5.1).
English: As a result of the potential to receive higher doses or a greater number of these medicinal products with filgrastim therapy, the patient may be at higher risk of developing thrombocytopenia and anaemia.
Slovenian: Ker lahko bolnik ob zdravljenju s filgrastimom prejme večje odmerke ali večje število takšnih zdravil, je bolnik lahko izpostavljen večjemu tveganju za razvoj trombocitopenije in anemije.
English: Telephone +420/257-888.111
Slovenian: Tel: +420/257-888.111
English: Reversal of neutropenia or maintaining normal neutrophil counts: Grastofil should be given by subcutaneous injection.
Slovenian: Za odpravo nevtropenije ali vzdrževanje normalnega števila nevtrofilcev: Grastofil je treba dati s subkutano injekcijo.
English: Grastofil contains the active substance filgrastim.
Slovenian: Zdravilo Grastofil vsebuje učinkovino filgrastim.
English: Leukapheresis should be performed during the period when the ANC rises from < 0.5 x 10
Slovenian: Levkaferezo je treba narediti v obdobju, ko se absolutno število nevtrofilcev dvigne z ravni < 0,5 x 10
English: • enlargement of the liver (hepatomegaly)
Slovenian: • povečanje jeter (hepatomegalija)
English: België/Belgique/Belgien Eurogenerics SA/NV Telephone +32/2.479.78.78
Slovenian: België/Belgique/Belgien Eurogenerics SA/NV Tél/Tel: +32/2.479.78.78
English: The onset of pulmonary signs such as cough, fever and dyspnoea in association with radiological signs of pulmonary infiltrates and deterioration in pulmonary function may be preliminary signs of Acute Respiratory Distress Syndrome (ARDS).
Slovenian: Začetek pojavljanja pljučnih znakov, kot so na primer kašelj, zvišana telesna temperatura in dispneja ob hkratnih radioloških znakih pljučnih infiltratov in ob slabšanju delovanja pljuč, lahko pomeni začetek sindroma akutne dihalne stiske (ARDS - Acute Respiratory Distress Syndrome).
English: Increased haematopoietic activity of the bone marrow in response to growth factor therapy has been associated with transient abnormal bone scans.
Slovenian: Povečana krvotvorna aktivnost kostnega mozga kot odziv na zdravljenje z rastnim faktorjem je povezana s prehodnimi nenormalnimi izvidi slikanja kosti.
English: Premature discontinuation of Grastofil therapy, prior to the time of the expected neutrophil nadir, is not recommended.
Slovenian: Prezgodnja prekinitev zdravljenja z Grastofilom, preden število nevtrofilcev pade na pričakovano najnižjo raven, ni priporočljiva.
English: Your doctor may then test your blood to see how well your treatment with Grastofil is working and to find the dose that is best for you.
Slovenian: Potem bo morda zdravnik opravil krvno preiskavo, da ugotovi, kako dobro deluje zdravljenje z zdravilom Grastofil, in da bo določil za vas najprimernejši odmerek.
English: Grastofil and severe chronic neutropenia (low number of a type of white blood cells)
Slovenian: Zdravilo Grastofil in huda kronična nevtropenija (nizko število vrste belih krvnih celic)
English: There have been reports of graft versus host disease (GvHD) and fatalities in patients receiving G-CSF after allogeneic bone marrow transplantation (see section 4.8 and 5.1).
Slovenian: Poročali so o reakcijah presadka proti gostitelju (GvHD - Graft versus Host Disease) in o smrtnih primerih pri bolnikih, ki so G-CSF prejemali po alogenski presaditvi kostnega mozga (glejte poglavji 4.8 in 5.1).
English: Special precautions in patients undergoing PBPC mobilisation
Slovenian: Posebni varnostni ukrepi za bolnike, pri katerih se izplavljajo PBPC
English: Once the neutrophil nadir has been passed, the daily dose of Grastofil should be titrated against the neutrophil response as follows:
Slovenian: Ko obdobje najnižjega števila nevtrofilcev mine, je treba dnevni odmerek Grastofila prilagoditi glede na odziv nevtrofilcev kot sledi:
English: Long-term daily administration is required to maintain an adequate neutrophil count.
Slovenian: Za vzdrževanje ustreznega števila nevtrofilcev je potrebna dolgotrajna vsakodnevna uporaba zdravila.
English: Treatment with filgrastim significantly reduces the duration of febrile neutropenia, antibiotic use and hospitalisation after induction chemotherapy for acute myelogenous leukaemia or myeloablative therapy followed by bone marrow transplantation.
Slovenian: Zdravljenje s filgrastimom znatno zmanjša trajanje febrilne nevtropenije, uporabo antibiotikov in hospitalizacijo po začetku uvedbe kemoterapije za akutno mielogeno levkemijo ali po mieloablacijski terapiji, ki ji sledi presaditev kostnega mozga.
English: The safety and efficacy of Grastofil are similar in adults, children and adolescents receiving cytotoxic chemotherapy.
Slovenian: Varnost in učinkovitost zdravila Grastofil sta podobni pri odraslih, otrocih in mladostnikih, ki dobivajo citotoksično kemoterapijo.
English: Centrafarm BV Telephone +31/7650.81.000
Slovenian: Nederland Centrafarm BV Tel: +31/7650.81.000
English: • unusual hair loss or thinning (alopecia)
Slovenian: • neobičajno izpadanje ali tanjšanje las (alopecija)
English: Special precautions in recipients of allogeneic PBPC mobilised with filgrastim Current data indicate that immunological interactions between the allogeneic PBPC graft and the recipient may be associated with an increased risk of acute and chronic GvHD when compared with bone marrow transplantation.
Slovenian: Posebni ukrepi za prejemnike alogenskih PBPC, izplavljenih s filgrastimom Trenutni podatki kažejo, da so lahko imunološka medsebojna delovanja med presajenimi alogenskimi PBPC in prejemnikom v primerjavi s presaditvijo kostnega mozga povezane z večjim tveganjem za akutno in kronično reakcijo presadka proti gostitelju (GvHD).
English: Telephone +48/22 -737.79.20
Slovenian: Tel: +48/22 -737.79.20
English: You do not need to remove the air bubble before injecting.
Slovenian: Pred injiciranjem vam zračnega mehurčka ni treba odstraniti.
English: Clearance of filgrastim has been shown to follow first-order pharmacokinetics after both subcutaneous and intravenous administration.
Slovenian: Kaže, da sledi očistek filgrastima farmakokinetiki prvega reda tako pri subkutani kot pri intravenski uporabi.
English: • notice unusual bleeding or bruising (these may be symptoms of a decrease in blood platelets (thrombocytopenia), with a reduced ability of your blood to clot).
Slovenian: • opazite neobičajno krvavitev ali modrice (to so lahko simptomi zmanjšanja števila trombocitov (trombocitopenija), z zmanjšano sposobnostjo strjevanja krvi).
English: In a small number of patients (< 10%), doses up to 1.0 MU/kg/day (10 micrograms/kg/day) were required to achieve reversal of neutropenia.
Slovenian: Pri majhnem številu bolnikov (< 10 %) so bili za odpravo nevtropenije potrebni odmerki do 1,0 M e./kg/dan (10 mikrogramov/kg/dan).
English: Mobilisation of PBPC does not provide a direct clinical benefit to normal donors and should only be considered for the purposes of allogeneic stem cell transplantation.
Slovenian: Izplavljanje matičnih celic v periferno kri zdravim darovalcem ne prinaša neposrednih kliničnih koristi, zato je namenjeno le alogenski presaditvi matičnih celic.
English: • severe pain in the bones, chest, gut or joints (sickle cell anaemia with crisis)
Slovenian: • hude bolečine v kosteh, prsnem košu, črevesju ali sklepih (srpastocelična anemija s krizo)
English: The dose recommendations in paediatric patients are the same as those in adults receiving myelosuppressive cytotoxic chemotherapy.
Slovenian: Priporočeni odmerki za pediatrične bolnike so enaki kot za odrasle osebe, ki prejemajo mielosupresivno citotoksično kemoterapijo.
English: Grastofil and peripheral blood stem cell transplantation (stem cells collected from the blood to use in bone marrow transplantation)
Slovenian: Zdravilo Grastofil in presaditev matičnih celic iz periferne krvi (matične celice, zbrane v krvi, ki se uporabljajo za presaditev kostnega mozga)
English: • you experience an allergic reaction including weakness, drop in blood pressure, difficulty breathing, swelling of the face (anaphylaxis), skin rash, itchy rash (urticaria), swelling of the face, lips, mouth, tongue or throat (angioedema) and shortness of breath (dyspnoea).
Slovenian: • se pri vas pojavi alergijska reakcija, vključno s šibkostjo, padcem krvnega tlaka, težavami z dihanjem, oteklostjo obraza (anafilaksa), kožnim izpuščajem, srbečim izpuščajem (urtikarija), oteklostjo obraza, ustnic, ust, jezika ali žrela (angioedem) in kratko sapo (dispneja).
English: Grastofil and neutropenia (low number of a type of white blood cells) in patients with HIV infection
Slovenian: Zdravilo Grastofil in nevtropenija (nizko število vrste belih krvnih celic) pri bolnikih, okuženih s HIV
English: Uncommon (≥ 1/1,000 to <
Slovenian: Občasni (≥ 1/1.000 do <
English: This is known as a subcutaneuous injection.
Slovenian: To je t.i. subkutana injekcija.
English: cells/kg recipient body weight in the majority of the donors after two leukaphereses.
Slovenian: +/kg telesne mase prejemnika po dveh levkaferezah.
English: Luxembourg/Luxemburg Eurogenerics SA/NV Telephone +32/2.479.78.78
Slovenian: Luxembourg/Luxemburg Eurogenerics SA/NV Tél/Tel: +32/2.479.78.78
English: Grastofil may be given as a 24 hour subcutaneous continuous infusion or subcutaneous injection.
Slovenian: Grastofil se lahko daje v obliki stalne 24-urne subkutane infuzije ali subkutane injekcije.
English: • you have any of the following or a combination of the following side effects: o swelling or puffiness, which may be associated with passing water less frequently, difficulty breathing, abdominal swelling and feeling of fullness, and a general feeling of tiredness.
Slovenian: • opazite katerega koli od naslednjih neželenih učinkov ali kombinacijo naslednjih neželenih učinkov: o otekanje ali zabuhlost, ki lahko nastopita v povezavi z zmanjšano pogostostjo uriniranja, težave z dihanjem, otekanje trebuha in občutek polnosti ter splošen občutek utrujenosti.
English: Recipients of allogeneic PBPCs mobilised with filgrastim experienced significantly more rapid haematological recovery, leading to a significant decrease in time to unsupported platelet recovery when compared with allogeneic bone marrow transplantation.
Slovenian: Prejemniki alogenskih PBPC, izplavljenih s filgrastimom, so veliko prej hematološko okrevali, kar je močno zmanjšalo čas do obnove trombocitov brez podpore v primerjavi z alogensko presaditvijo kostnega mozga.
English: Telephone +34/93-473.88.89
Slovenian: Tel: +34/93-473.88.89
English: Medicinal products such as melphalan, carmustine (BCNU) and carboplatin, when administered over prolonged periods prior to attempts at progenitor mobilisation, may reduce progenitor yield.
Slovenian: Dalj časa trajajoče dajanje zdravil, kot so melfalan, karmustin (BCNU) in karboplatin pred samim poskusom izplavljanja matičnih celic lahko povzroči zmanjšanje števila izplavljenih matičnih celic.
English: • The other ingredients are glacial acetic acid, sodium hydroxide, sorbitol (E420), polysorbate 80 and water for injections.
Slovenian: • Druge sestavine zdravila so ledocetna kislina, natrijev hidroksid, sorbitol (E420), polisorbat 80 in voda za injekcije.
English: • abnormal x-rays of the lungs (lung infiltration)
Slovenian: • nenormalni rentgenski izvidi pljuč (pljučni infiltrati)
English: Transformation to leukaemia or myelodysplastic syndrome Special care should be taken in the diagnosis of SCNs to distinguish them from other haematopoietic disorders such as aplastic anaemia, myelodysplasia and myeloid leukaemia.
Slovenian: Preobrazba v levkemijo ali mielodisplastični sindrom Posebna pozornost je potrebna pri diagnosticiranju hudih kroničnih nevtropenij, da bi jih lahko razlikovali od drugih motenj hematopoeze, kot na primer aplastične anemije, mielodisplazije in mieloične levkemije.
English: These autologous PBPCs may be harvested and infused after high-dose cytotoxic therapy, either in place of, or in addition to bone marrow transplantation.
Slovenian: Te avtologne matične celice (PBPC) je mogoče odvzeti in jih infundirati po citotoksičnem zdravljenju z velikimi odmerki, bodisi namesto presaditve kostnega mozga ali kot dodatek k njej.
English: Dose reductions of filgrastim have been noted to slow or stop the progression of splenic enlargement in patients with severe chronic neutropenia, and in 3% of patients a splenectomy was required.
Slovenian: Opazili so, da pri bolnikih s hudo kronično nevtropenijo zmanjšanje odmerka filgrastima upočasni ali ustavi napredovanje povečanja vranice, pri 3 % bolnikov pa je bila potrebna splenektomija.
English: Adverse events with higher incidence in filgrastim patients compared to placebo and associated with the sequelae of the underlying malignancy or cytotoxic chemotherapy
Slovenian: Neželeni učinki z večjo pojavnostjo pri bolnikih na filgrastimu v primerjavi s placebom in v povezavi s posledicami osnovne malignosti ali citotoksične kemoterapije
English: There were no differences in the safety profiles for paediatric patients treated for SCN.
Slovenian: V profilih varnosti za pediatrične bolnike, zdravljene zaradi hude kronične nevtropenije, ni bilo razlik.
English: The effects of filgrastim on neutropenia due to bone marrow-infiltrating infection or malignancy have not been well established.
Slovenian: Učinki filgrastima na nevtropenijo, ki je posledica infiltracije kostnega mozga z okužbo ali malignega obolenja, niso dobro raziskani.
English: • to increase the number of white blood cells if you suffer from severe chronic neutropenia to help prevent infections;
Slovenian: • za povečanje števila belih krvnih celic, če trpite zaradi hude kronične nevtropenije, za pomoč pri preprečevanju okužb;
English: Grastofil is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes) and for the reduction in the duration of neutropenia in patients undergoing myeloablative therapy followed by bone marrow transplantation considered to be at increased risk of prolonged severe neutropenia.
Slovenian: Zdravilo Grastofil je indicirano za skrajšanje trajanja nevtropenije in v primeru nastanka febrilne nevtropenije pri bolnikih, ki prejemajo citotoksično kemoterapijo za maligne tvorbe (z izjemo kronične mieloične levkemije in mielodisplastičnih sindromov), ter za skrajšanje trajanja nevtropenije pri bolnikih, ki se zdravijo z mieloablativno terapijo, ki ji sledi presaditev kostnega mozga, pri katerih obstaja povečano tveganje za dlje trajajočo hudo nevtropenijo.
English: Dizziness may occur following the administration of filgrastim (see section 4.8).
Slovenian: Po dajanju filgrastima se lahko pojavi omotica (glejte poglavje 4.8).
English: • you have a combination of any of the following symptoms: o fever, or shivering, or feeling very cold, high heart rate, confusion or disorientation, shortness of breath, extreme pain or discomfort and clammy or sweaty skin.
Slovenian: • imate kombinacijo katerih od naslednjih simptomov: o zvišana telesna temperatura ali tresenje ali občutek mrazu, hiter srčni utrip, zmedenost ali dezorientiranost, zasoplost, izjemne bolečine ali nelagodje in lepljiva ali potna koža.
English: Grastofil and bone marrow transplantation
Slovenian: Zdravilo Grastofil in presaditev kostnega mozga
English: The no observed adverse effect level for embryo-fetal toxicity in this study was 10 μg/kg/day, which corresponded to a systemic exposure of approximately 3-5 times the exposures observed in patients treated with the clinical dose.
Slovenian: V tej študiji je znašal odmerek brez opaznih neželenih učinkov za toksičnost zarodka oz. ploda 10 mikrogramov/kg/dan, kar ustreza sistemski izpostavljenosti, ki je približno 3- do 5-krat večja od izpostavljenosti, ki so jo zabeležili pri bolnikih, ki so prejemali klinični odmerek.
English: • sickle cell anaemia, as filgrastim can cause sickle cell crisis.
Slovenian: • srpastocelično anemijo, saj lahko filgrastim povzroči srpastocelično krizo.
English: • a change in how your body regulates fluids within your body and may result in puffiness (fluid volume disturbances)
Slovenian: • spremenjen način telesnega reguliranja tekočin v telesu, ki lahko povzroči zabuhlost (motnje volumna tekočin)
English: Risk associated with increased doses of myelosuppressive medications Treatment with filgrastim alone does not preclude thrombocytopenia and anaemia due to myelosuppressive medicinal products.
Slovenian: Tveganje, povezano s povečanimi odmerki mielosupresivnih zdravil Zdravljenje s filgrastimom samim ne prepreči trombocitopenije in anemije, povzročenih z mielosupresivnimi zdravili.
English: No overall differences in safety or effectiveness were observed between subjects over 65 years of age compared to younger adult (>18 years of age) subjects receiving cytotoxic chemotherapy and clinical experience has not identified differences in the responses between elderly and younger adult patients.
Slovenian: V splošnem niso ugotovili razlik v varnosti in učinkovitosti med osebami, starejšimi od 65 let, v primerjavi z mlajšimi odraslimi osebami (> 18 let), ki so prejemale citotoksično kemoterapijo.
English: • high uric acid levels in the blood, which may cause gout (hyperuricaemia) (Blood uric acid increased)
Slovenian: • zvišane ravni sečne kisline v krvi, kar lahko povzroči protin (hiperurikemijo)
English: Special precautions in patients with HIV infection
Slovenian: Posebni previdnostni ukrepi pri bolnikih, okuženih s HIV
English: Grastofil contains sorbitol
Slovenian: Zdravilo Grastofil vsebuje sorbitol
English: Your doctor may test your blood at regular intervals to see how well the Grastofil treatment is working.
Slovenian: Vaš zdravnik bo redno izvajal krvne preiskave, da ugotovi, kako dobro deluje zdravljenje z zdravilom Grastofil.
English: During intermittent dosing with 30 MU (300 microgram)/day of filgrastim, there can be wide fluctuations in the patient's ANC over time.
Slovenian: Med intermitentno uporabo filgrastima v odmerku 30 M e./dan (300 mikrogramov/dan) lahko sčasoma pride do velikih nihanj ANC.
English: Do not use this medicine after the expiry date which is stated on the outer carton and on the pre-filled syringe after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na zunanji ovojnini in na napolnjeni injekcijski brizgi poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
English: • redness of the skin (erythema)
Slovenian: • rdečina kože (eritem)
English: How to use Grastofil
Slovenian: Kako uporabljati zdravilo Grastofil