FrancophonIA/ELRC3.0 huggingface dataset:
English: Efavirenz must not be administered concurrently with terfenadine, astemizole, cisapride, midazolam, triazolam, pimozide, bepridil, or ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine), since inhibition of their metabolism may lead to serious, life-threatening events (see section 4.3).
Slovenian: Efavirenza se ne sme jemati hkrati s terfenadinom, astemizolom, cisapridom, midazolamom, triazolamom, pimozidom, bepridilom ali ergot alkaloidi (npr. ergotaminom, dihidroergotaminom, ergonovinom in metilergonovinom), ker zaviranje njihovega metabolizma lahko povzroči resne,
English: There is a potential for reduction or increase in the plasma concentrations of phenytoin, phenobarbital and other anticonvulsants that are substrates of CYP450 isoenzymes when co-administered with efavirenz.
Slovenian: Pri sočasni uporabi z efavirenzem obstaja možnost zmanjšanja ali povečanja plazemskih koncentracij fenitoina, fenobarbitala in drugih antikonvulzivov, ki so substrati za izoencime CYP450.
English: The recommended dose of efavirenz in combination with nucleoside analogue reverse transcriptase inhibitors (NRTIs) with or without a PI (see section 4.5) is 600 mg orally, once daily.
Slovenian: V kombinaciji z nukleozidnimi zaviralci reverzne transkriptaze (NRTI), z ali brez ZP, je priporočeni odmerek zdravila efavirenz 600 mg peroralno, enkrat na dan (glejte poglavje 4.5).
English: What Efavirenz Teva looks like and contents of the pack
Slovenian: Izgled zdravila Efavirenz Teva in vsebina pakiranja
English: Thirty-seven patients 3 months to 6 years of age (median 0.7 years) were treated with efavirenz.
Slovenian: Z efavirenzem se je zdravilo sedemintrideset bolnikov, starih od 3 mesecev do 6 let (mediana 0,7 leta).
English: Artemether/lumefantrine/efaviren z (20/120 mg tablet, 6 doses of 4 tablets each over 3 days/600mg once daily)
Slovenian: Antimalariki artemeter/lumefantrin/ efavirenz (20/120 mg tablete, 6 odmerkov po 4 tablete v 3 dneh /600 mg enkrat na dan)
English: The median time on study therapy was 181 weeks; 16% of patients discontinued before Week 48.
Slovenian: 181 tednov; 16 % bolnikov je zdravljenje prekinilo pred 48. tednom.
English: Cellulose, microcrystalline Hydroxypropylcellulose Sodium laurilsulfate Sodium starch glycolate (Type A) Poloxamer 407
Slovenian: Jedro mikrokristalna celuloza hidroksipropilceluloza natrijev lavrilsulfat natrijev karboksimetilškrob (vrsta A) poloksamer 407 magnezijev stearat
English: Depomedroxyprogesterone acetate (DMPA)/efavirenz (150 mg IM single dose DMPA)
Slovenian: injekcija: depomedroksiprogesteronacetat (DMPA)/efavirenz (150 mg i.m.
English: Morning Cmin: ↑ 42% (↑ 9 to ↑ 86)
Slovenian: Cmin zjutraj: ↑ 42 % (↑ 9 do ↑ 86)b
English: If the co-administration of atazanavir with an NNRTI is required, an increase in the dose of both atazanavir and ritonavir to 400 mg and 200 mg, respectively, in combination with efavirenz could be considered with close clinical monitoring.
Slovenian: Če je v kombinaciji z efavirenzem potrebna sočasna uporaba atazanavirja in NNRTI, lahko po potrebi in ob skrbnem kliničnem spremljanju povečate odmerek atazanavirja na 400 mg in odmerek ritonavirja na 200 mg.
English: The median time on study therapy was 132 weeks; 27% of patients discontinued before Week 48.
Slovenian: 132 tednov; 27 % bolnikov je zdravljenje prekinilo pred 48. tednom.
English: AUC: ↑ 34% (↑ 18 to ↑ 53) Cmax: ↑ 49% (↑ 32 to ↑ 69)
Slovenian: AUC: ↑ 34 % (↑ 18 do ↑ 53) Cmax: ↑ 49 % (↑ 32 do ↑ 69)
English: Efavirenz Teva contains sodium
Slovenian: Zdravilo Efavirenz Teva vsebuje natrij
English: Pimozide, imipramine, amitriptyline or clomipramine (used to treat certain mental conditions) elbasvir or grazoprevir (used to treat hepatitis C) St John's wort (Hypericum perforatum) (a herbal remedy used for depression and anxiety) flecainide, metoprolol (used to treat irregular heart beat) certain antibiotics (macrolides, fluoroquinolones, imidazole)
Slovenian: pimozid, imipramin, amitriptilin ali klomipramin (za zdravljenje določenih duševnih stanj) elbasvir ali grazoprevir (za zdravljenje hepatitisa C) šentjanževko (Hypericum perforatum) (rastlinski pripravek, ki se uporablja pri depresiji in tesnobi)
English: If you are currently taking any of the following medicines (see also “Other medicines and Efavirenz Teva): Astemizole or terfenadine (used to treat allergy symptoms) Bepridil (used to treat heart disease) Cisapride (used to treat heartburn)
Slovenian: - če trenutno jemljete katero koli od naslednjih zdravil (glejte tudi "Druga zdravila in zdravilo Efavirenz Teva"): astemizol ali terfenadin (za zdravljenje alergijskih simptomov) bepridil (za zdravljenje bolezni srca) - cisaprid (za zdravljenje zgage) - ergot alkaloide (kot na primer ergotamin, dihidroergotamin, ergonovin in metilergonovin) (za zdravljenje migrene in klaster glavobolov)
English: imidazole and triazole antifungal agents, - certain non-sedating antihistamines (terfenadine, astemizole), - cisapride, - flecainide, - certain antimalarials, - methadone.
Slovenian: imidazoli in triazolski antimikotiki, določeni nesedativni antihistaminiki (terfenadin, astemizol),
English: Cmax: ↓ 17% (↓ 6 to ↓ 26) b Cmin: ↓ 50% (↓ 40 to ↓ 59)
Slovenian: Cmax : ↓ 17 % (↓ 6 do ↓ 26)b Cmin : ↓ 50 % (↓ 40 do ↓ 59)
English: Evening Cmin: ↑ 24% (↑ 3 to ↑ 50) b
Slovenian: Cmin zvečer: ↑ 24 % (↑ 3 do ↑ 50)
English: LIPID-LOWERING MEDICINAL PRODUCTS HMG CoA Reductase Inhibitors Atorvastatin/efavirenz (10 mg once daily/600 mg once daily)
Slovenian: ZDRAVILA ZA ZMANJŠANJE RAVNI LIPIDOV Zaviralci HMG Co-A-reduktaze atorvastatin/efavirenz (10 mg enkrat na dan/600 mg enkrat na dan)
English: Methadone/efavirenz (stable maintenance, 35-100 mg once daily/600 mg once daily)
Slovenian: OPIOIDI metadon/efavirenz (stabilno vzdrževanje, 35-100 mg enkrat na dan/600 mg enkrat na dan)
English: Study PACTG 1021 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with didanosine and emtricitabine in paediatric patients who were antiretroviral therapy naive.
Slovenian: Študija PACTG 1021 je bila odprta študija za oceno farmakokinetike, varnosti, prenašanja in protivirusnega delovanja efavirenza v kombinaciji z didanozinom in emtricitabinom pri pediatričnih bolnikih, ki še niso bili zdravljeni s protiretrovirusnimi zdravili.
English: - The other ingredients are cellulose microcrystalline, hydroxypropylcellulose, sodium laurilsulfate, sodium starch glycolate (Type A), poloxamer 407 and magnesium stearate in the core.
Slovenian: Jedro tablete: mikrokristalna celuloza, hidroksipropilceluloza, natrijev lavrilsulfat, natrijev karboksimetilškrob (vrsta A), poloksamer 407 in magnezijev stearat.
English: Long-term results at 168 weeks of study 006 (160 patients completed study on treatment with EFV+IDV, 196 patients with EFV+ZDV+3TC and 127 patients with IDV+ZDV+3TC, respectively), suggest durability of response in terms of proportions of patients with HIV-RNA < 400 copies/ml, HIV-RNA < 50 copies/ml and in terms of mean change from baseline CD4 cell count.
Slovenian: IDV, 196 bolnikov, zdravljenih z EFV + ZDV + 3TC, in 127 bolnikov, zdravljenih z IDV + ZDV + 3TC) kažejo na dolgotrajnost odziva glede na deleže bolnikov s HIV RNA < 400 kopij/ml, HIV
English: Carbamazepine may make Efavirenz Teva less likely to work.
Slovenian: Karbamazepin lahko zmanjša delovanje zdravila Efavirenz Teva.
English: Co-administration of higher doses of either efavirenz or carbamazepine has not been studied.
Slovenian: Sočasne uporabe večjih odmerkov obeh, efavirenza ali karbamazepina,
English: Dose adjustment of buprenorphine or efavirenz may not be necessary when co-administered.
Slovenian: Pri sočasni uporabi prilagoditev odmerka buprenorfina ali efavirenza lahko ni potrebna.
English: Selective Serotonin Reuptake Inhibitors (SSRIs) Sertraline/efavirenz (50 mg once daily/600 mg once daily)
Slovenian: Selektivni zaviralci ponovnega privzema serotonina (SSRI) sertralin/efavirenz (50 mg enkrat na dan/600 mg enkrat na dan)
English: 006 on a subset of 614 patients who had been enrolled for at least 48 weeks are found in Table 2.
Slovenian: Rezultate učinkovitosti študije 006 pri podskupini 614 bolnikov, vključenih vsaj
English: EU/1/11/742/001 (30 x 1 - blister PVC/PVDC/alu) EU/1/11/742/006 (30 x 1 - blister alu/alu)
Slovenian: EU/1/11/742/001 (30 x 1 - pretisni omot PVC/PVDC/alu) EU/1/11/742/006 (30 x 1 - pretisni omot alu/alu)
English: Plasma levels of efavirenz can be reduced by concomitant use of St. John's wort due to induction of drug-metabolising enzymes and/or transport proteins by St. John's wort.
Slovenian: Sočasna uporaba šentjanževke lahko zmanjša koncentracije efavirenza v plazmi, ker šentjanževka inducira encime, ki presnavljajo zdravilo in/ali transportne proteine.
English: Study AI266922 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with didanosine and emtricitabine in antiretroviral-naive and -experienced paediatric patients.
Slovenian: Študija AI266922 je bila odprta študija za oceno farmakokinetike, varnosti, prenašanja in protivirusnega delovanja efavirenza v kombinaciji z didanozinom in emtricitabinom pri pediatričnih bolnikih, ki so že bili zdravljeni ali še niso bili zdravljeni s protiretrovirusnimi zdravili.
English: No clinically significant pharmacokinetic interaction
Slovenian: Ni klinično pomembnih farmakokinetičnih interakcij.
English: Immune system disorders Uncommon Hypersensitivity Metabolism and nutrition disorders common hypertriglyceridaemia* uncommon hypercholesterolaemia*
Slovenian: Presnovne in prehranske motnje pogosti hipertrigliceridemija*
English: AUC: ↓ 83% (↓ 79 to ↓ 87) Cmax: ↓ 80% (↓ 77 to ↓ 83) Cmin: ↓ 86% (↓ 80 to ↓ 90)
Slovenian: AUC: ↓ 83 % (↓ 79 do ↓ 87) Cmax: ↓ 80 % (↓ 77 do ↓ 83) Cmin: ↓ 86 % (↓ 80 do ↓ 90)
English: ANTICOAGULANTS Warfarin/efavirenz Acenocoumarol/efavirenz
Slovenian: ANTIKOAGULANTI varfarin/efavirenz acenokumarol/efavirenz
English: Uncommon (affects 1 to 10 users in 1,000)
Slovenian: Občasni (pojavijo se pri 1 do 10 od 1.000 bolnikov)
English: AUC: ↑ 20% (↑ 8 to ↑ 34) Cmax: ↑ 21% (↑ 10 to ↑ 33)
Slovenian: AUC: ↑ 20 % (↑ 8 do ↑ 34) Cmax : ↑ 21 % (↑ 10 do ↑ 33)
English: AUC: ↑ 21% (↑ 10 to ↑ 34) Cmax: ↑ 14% (↑ 4 to ↑ 26) Cmin: ↑ 25% (↑ 7 to ↑ 46)
Slovenian: AUC: ↑ 21 % (↑ 10 do ↑ 34) Cmax: ↑ 14 % (↑ 4 do ↑ 26) Cmin: ↑ 25 % (↑ 7 do ↑ 46)b
English: - Efavirenz Teva is for oral use.
Slovenian: - Učinkovina je efavirenz.
English: - Once you start taking Efavirenz Teva, look out for: signs of dizziness, difficulty sleeping, drowsiness, difficulty concentrating or abnormal dreaming.
Slovenian: če imate motnjo v delovanju srca, kot je nenormalen električni signal, ki se imenuje podaljšanje intervala QT. - Ko začnete jemati zdravilo Efavirenz Teva, bodite pozorni na: znake omotice, oteženo spanje, zaspanost, težave s koncentracijo ali nenormalne sanje.
English: Efavirenz is a non-competitive inhibitor of HIV-1 reverse transcriptase (RT) and does not significantly inhibit HIV-2 RT or cellular DNA polymerases (α, β, γ or δ).
Slovenian: in ne zavira pomembno RT HIV-2 ali celičnih polimeraz DNA (α, β, γ ali δ).
English: Efavirenz Teva 600 mg film-coated tablets Efavirenz
Slovenian: Efavirenz Teva 600 mg filmsko obložene tablete efavirenz
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Slovenian: (AIDS) in z oportunistično okužbo v anamnezi se lahko kmalu po začetku anti-HIV
English: (CYP3A4 induction) Co-administration of efavirenz with atorvastatin, pravastatin, or simvastatin did not affect efavirenz AUC or Cmax values.
Slovenian: Sočasna uporaba efavirenza z atorvastatinom, pravastatinom ali simvastatinom ni vplivala na vrednosti AUC ali Cmax efavirenza.
English: Ethinyloestradiol + norgestimate / efavirenz (0.035 mg + 0.25 mg once daily/600 mg once daily)
Slovenian: HORMONSKI KONTRACEPTIVI peroralni: etinilestradiol+norgestimat/efavir enz (0,035 mg+0,25 mg enkrat na dan/600 mg enkrat na dan)
English: Morning AUC: ↑ 18% (↑ 6 to ↑ 33) Evening AUC: ↔
Slovenian: AUC zjutraj: ↑ 18 % (↑ 6 do ↑ 33) AUC zvečer: ↔ Cmax zjutraj: ↑ 24 %
English: Voriconazole:
Slovenian: vorikonazol:
English: Grapefruit juice should be avoided when taking Efavirenz Teva.
Slovenian: Med jemanjem zdravila Efavirenz Teva se je potrebno izogibati uživanju soka grenivke.
English: voriconazole.
Slovenian: vorikonazol.
English: Desacetyl diltiazem:
Slovenian: desacetildiltiazem:
English: Because of the extensive cytochrome P450-mediated metabolism of efavirenz and limited clinical experience in patients with chronic liver disease, caution must be exercised in administering efavirenz to patients with mild hepatic impairment.
Slovenian: in omejenih kliničnih izkušenj pri bolnikih s kronično boleznijo jeter je potrebna previdnost pri predpisovanju efavirenza bolnikom z blago okvaro jeter.
English: Efavirenz Teva may reduce the amount of itraconazole in your blood.
Slovenian: Zdravilo Efavirenz Teva lahko zmanjša količino itrakonazola v krvi.
English: There have been occasional postmarketing reports of contraceptive failure with etonogestrel in efavirenz-exposed patients.
Slovenian: V obdobju trženja zdravila so pri bolnikih, ki so prejemali etonogestrel in efavirenz, občasno poročali o nezadostnem delovanju kontraceptiva.
English: Telaprevir/efavirenz (1,125 mg q8h/600 mg once daily)
Slovenian: telaprevir/efavirenz (1,125 mg q8h/600 mg enkrat na dan)
English: AUC12: ↓ 45% (↓ 38 to ↓ 51) Cmax: ↓ 51% (↓ 37 to ↓ 62)
Slovenian: AUC12: ↓ 45% (↓ 38 do ↓51) Cmax: ↓ 51% (↓ 37 do ↓ 62)
English: - Film-coated tablet: yellow, capsule-shaped, film-coated tablet debossed with “Teva” on one side and “7541” on the other - Efavirenz Teva is available in pack sizes of 30, 90 film-coated tablets or 30 x 1 / 90 x 1 film-coated tablets (in perforated unit dose blisters) or a multi-pack bundle or carton containing 90 film-coated tablets (3 packs of 30 x 1 film-coated tablet).
Slovenian: - Pakiranja: 30, 90 filmsko obloženih tablet ali 30 x 1 / 90 x 1 filmsko obložena tableta (v perforiranem enoodmernem pretisnem omotu) ali kot omot ali škatla, ki vsebuje 90 filmsko obloženih tablet (3 škatle po 30 x 1 filmsko obloženo tableto).
English: The administration of efavirenz with food may increase efavirenz exposure and may lead to an increase in the frequency of adverse reactions (see section 4.4).
Slovenian: Pri zaužitju zdravila efavirenz skupaj s hrano se lahko poveča izpostavitev efavirenzu in lahko pride do večje pogostnosti neželenih učinkov (glejte poglavje 4.4).
English: Efavirenz Teva can reduce or increase the amount of anticonvulsant in your blood.
Slovenian: Zdravilo Efavirenz Teva lahko zmanjša ali poveča količino zdravila proti krčem v krvi.
English: Since fluoxetine shares a similar metabolic profile with paroxetine, i.e. a strong CYP2D6 inhibitory effect, a similar lack of interaction would be expected for fluoxetine.
Slovenian: Ker ima fluoksetin podoben presnovni profil kot paroksetin, tj. močno zavira
English: AUC: ↑ 17% (↑ 6 to ↑ 29) ** Cmax: ↔** *compared to 200 mg twice daily alone ** compared to 600 mg once daily alone (Competitive inhibition of oxidative metabolism)
Slovenian: *v primerjavi z 200 mg samim dvakrat na dan **v primerjavi s 600 mg samim enkrat na dan (kompetitivno zaviranje oksidativne presnove)
English: Common Abdominal pain, diarrhoea, nausea, vomiting Uncommon Pancreatitis
Slovenian: Bolezni prebavil pogosti bolečine v trebuhu, driska, navzea, bruhanje občasni pankreatitis
English: d EFV, efavirenz; ZDV, zidovudine; 3TC, lamivudine; IDV, indinavir.
Slovenian: a NK = NA, ni končal = napaka analize b IZ, interval zaupanja c S.N.P., standardna napaka povprečja d EFV, efavirenz; ZDV, zidovudin; 3TC, lamivudin; IDV, indinavir.
English: - Efavirenz Teva should never be used alone to treat HIV.
Slovenian: - Zdravilo Efavirenz Teva je treba jemati vsak dan. - Za zdravljenje HIV ne smete nikoli uporabljati zdravila Efavirenz Teva samega.
English: Experience with efavirenz in patients who discontinued other antiretroviral agents of the NNRTI class is limited.
Slovenian: Pri bolnikih, ki so prenehali jemati druga protiretrovirusna zdravila iz razreda NNRTI, je izkušenj z efavirenzem malo.
English: At baseline, median plasma HIV-1 RNA was 4.57 log10 copies/mL, median CD4+ cell count was 755 cells/mm3, and median CD4+ percentage was 30%.
Slovenian: Ob izhodišču je ugotovljeno: mediana plazemsko HIV-1 RNA je bila 4,57 log10 kopij/ml, mediana števila celic CD4+ je bila 755 celic/mm3 in mediana odstotka CD4+ je bila 30 %.
English: In the analysis of responder rates (the non-completer equals failure analysis [NC = F]), patients who terminated the study early for any reason, or who had a missing HIV-RNA measurement that was either preceded or followed by a measurement above the limit of assay quantification were considered to have HIV-RNA above 50 or above 400 copies/ml at the missing time points.
Slovenian: (vrednost meritve pred ali za njo pa je bila nad mejo določitve testa), v manjkajočih časovnih točkah HIV-RNA vrednost izpuščene meritve nad 50 ali nad 400 kopij/ml.
English: At baseline, median plasma HIV-1 RNA was 4.8 log10 copies/mL, median CD4+ cell count was 367 cells/mm3, and median CD4+ percentage was 18%.
Slovenian: Ob izhodišču so imeli mediano plazemsko HIV-1 RNA 4,8 log10 kopij/ml, mediana števila celic CD4+ je znašala 367 celic/mm3 in mediana odstotka CD4+ je znašala 18 %.
English: Recommendation concerning co-administration with efavirenz immunosuppressants are not anticipated to affect exposure of efavirenz.
Slovenian: Pri teh imunosupresivih ne pričakujemo, da vplivajo na izpostavitev efavirenzu.
English: Study PACTG 382 was an open-label study to evaluate the pharmacokinetics, safety, tolerability, and antiviral activity of efavirenz in combination with nelfinavir and an NRTI in antiretroviral-naive and NRTI-experienced paediatric patients.
Slovenian: Študija PACTG 382 je bila odprta študija za oceno farmakokinetike, varnosti, prenašanja in protivirusnega delovanja efavirenza v kombinaciji z nelfinavirjem in nukleozidnim zaviralcem reverzne transkriptaze (NRTI) pri pediatričnih bolnikih, ki se še niso zdravili s protiretrovirusnimi zdravili, vendar so se že zdravili z NRTI.
English: Clarithromycin/efavirenz (500 mg q12h/400 mg once daily)
Slovenian: klaritromicin/efavirenz (500 mg q12h/400 mg enkrat na dan)
English: Cmax: ↑ 11% (↑ 6 to ↑ 16)
Slovenian: Cmax: ↑ 11 % (↑ 6 do ↑ 16) Cmin: ↔
English: Multipack (carton) containing 90 film-coated tablets (3 packs of 30 x 1 film-coated tablet) in white opaque PVC/PVdC-aluminium or aluminium-aluminium perforated unit-dose blisters.
Slovenian: Škatla z 90 filmsko obloženimi tabletami (3 škatle po 30x1 filmsko obloženo tableto v belem, prozornem PVC/PVdC-aluminij ali aluminij-aluminij perforiranem enodomernem pretisnem omotu).
English: If you are taking any of these medicines, your doctor may need to check the level of anticonvulsant medicine in your blood to ensure that it is not affected while taking Efavirenz Teva.
Slovenian: Če jemljete katero od naštetih zdravil, vam bo zdravnik morda preveril količino zdravila proti krčem v krvi.
English: Indinavir/efavirenz (800 mg q8h/200 mg once daily)
Slovenian: indinavir/efavirenz (800 mg q8h/200 mg enkrat na dan)
English: Clinical efficacy
Slovenian: Učinkovine po terapevtskih področjih
English: AUC: ↓ 60% (↓ 52 to ↓ 68) Cmax: ↓ 62% (↓ 55 to ↓ 78)
Slovenian: AUC: ↓ 60 % (↓ 52 do ↓ 68) Cmax: ↓ 62 % (↓ 55 do ↓ 78)
English: If you stop taking Efavirenz Teva When your Efavirenz Teva supply starts to run low, get more from your doctor or pharmacist.
Slovenian: Ko gre vaša zaloga zdravila Efavirenz Teva h koncu, si ga priskrbite pri zdravniku oz. farmacevtu.
English: Hepatitis C antivirals Boceprevir/efavirenz (800 mg 3 times daily/600 mg
Slovenian: Zdravila za zdravljenje hepatitisa C boceprevir/efavirenz (800 mg 3-krat na dan/600 mg enkrat na dan)
English: - You must remain under the care of your doctor while taking Efavirenz Teva.
Slovenian: - Med jemanjem zdravila Efavirenz Teva morate ostati pod nadzorom zdravnika.
English: AUC: ↓ 39% (↓ 21 to ↓ 53) Cmax: ↓ 37% (↓ 20 to ↓ 51) Cmin: ↓ 44% (↓ 27 to ↓ 58)
Slovenian: AUC: ↓ 39 % (↓ 21 do ↓ 53) Cmax: ↓ 37 % (↓ 20 do ↓ 51) Cmin: ↓ 44 % (↓ 27 do ↓ 58)
English: Norepinephrine and dopamine reuptake inhibitor Bupropion/efavirenz [150 mg single dose (sustained release)/600 mg once daily]
Slovenian: Zaviralec ponovnega privzema noradrenalina in dopamina bupropion/efavirenz [150 mg enkratni odmerek
English: The methadone dose was increased by a mean of 22% to alleviate withdrawal symptoms.
Slovenian: Za ublažitev odtegnitvenih simptomov so povečali odmerek metadona v povprečju za
English: In a single-dose study, half-life was doubled in the single patient with severe hepatic impairment (Child Pugh Class C), indicating a potential for a much greater degree of accumulation.
Slovenian: Okvara jeter V študiji z enkratnim odmerjanjem je bil pri edinem bolniku s hudo jetrno okvaro (razred C po Child
English: CCR5 antagonist Maraviroc/efavirenz (100 mg twice daily/600 mg once daily)
Slovenian: CCR5 antagonisti maravirok/efavirenz (100 mg dvakrat na dan/600 mg enkrat na dan)
English: Concomitant administration of sofosbuvir/velpatasvir with efavirenz resulted in a reduction (approximately 50%) in the systemic exposure of velpatasvir.
Slovenian: Sočasna uporaba efavirenza in sofosbuvira/velpatasvira je povzročila zmanjšanje (približno
English: ↔efavirenz
Slovenian: zaradi efavirenza.
English: Using an ITT analysis, the overall proportion of patients with HIV RNA <400 copies/mL and <50 copies/mL at Week 48 were 57% (58/102) and 43% (44/102), respectively.
Slovenian: V 48. tednu - pri uporabi analize ITT - je bil celotni delež bolnikov s HIV RNA < 400 kopij/ml 57 % (58/102) in celotni delež bolnikov s HIV RNA < 50 kopij/ml 43 %
English: Atazanavir/ritonavir/efavirenz (400 mg once daily/200 mg once daily/600 mg once daily, all administered with food)
Slovenian: atazanavir/ritonavir/efavirenz (400 mg enkrat na dan/200 mg enkrat na dan/600 mg enkrat na dan, vse s hrano)
English: How to store Efavirenz Teva
Slovenian: Shranjevanje zdravila Efavirenz Teva
English: artemether/lumefantrine: Efavirenz Teva may reduce the amount of artemether/lumefantrine in your blood atovaquone/proguanil: Efavirenz Teva may reduce the amount of atovaquone/proguanil in your blood.
Slovenian: artemeter/lumefantrin: zdravilo Efavirenz Teva lahko zmanjša količino artemetra/lumefantrina v krvi.
English: Simeprevir/efavirenz (150 mg once daily /600 mg once daily)
Slovenian: simeprevir/efavirenz (150 mg enkrat na dan/600 mg enkrat na dan)
English: Saquinavir/ritonavir/efavirenz
Slovenian: sakvinavir/ritonavir/efavirenz
English: Concomitant administration of velpatasvir/sofosbuvir/voxilaprevir with efavirenz is not recommended (see section 4.5).
Slovenian: Sočasne uporabe efavirenza in velpatasvira/sofosbuvira/voksilaprevira ne priporočamo (glejte poglavje 4.5).
English: AUC: ↓ 64% (↓ 62 to ↓ 67) Cmax: ↓ 46% (↓ 39 to ↓ 52) Cmin: ↓ 82% (↓ 79 to ↓ 85)
Slovenian: AUC: ↓ 64 % (↓ 62 do ↓ 67) Cmax: ↓ 46 % (↓ 39 do ↓ 52) Cmin: ↓ 82 % (↓ 79 do ↓ 85)
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant product information for these medicinal products.
Slovenian: B ali C, prosimo, preberite tudi ustrezne povzetke glavnih značilnosti teh zdravil.
English: CARDIOVASCULAR AGENTS Calcium Channel Blockers Diltiazem/efavirenz (240 mg once daily/600 mg once daily)
Slovenian: Zaviralci kalcijevih kanalčkov diltiazem/efavirenz (240 mg enkrat na dan/600 mg enkrat na dan)
English: Seizures
Slovenian: ZDRVILA
English: Fluoxetine/efavirenz
Slovenian: fluoksetin/efavirenz
English: ANTIHISTAMINES Cetirizine/efavirenz (10 mg single dose/600 mg once daily)
Slovenian: ANTIHISTAMINIKI cetirizin/efavirenz (enkratni odmerek 10 mg/600 mg enkrat na dan)
English: ANTICONVULSANTS Carbamazepine/efavirenz (400 mg once daily/600 mg once daily)
Slovenian: ANTIKONVULZIVI karbamazepin/efavirenz (400 mg enkrat na dan/600 mg enkrat na dan)