FrancophonIA/ELRC3.0 huggingface dataset:
English: Desiccant should not be swallowed.
Croatian: Sredstvo za sušenje se ne smije progutati.
English: A dose reduction of indinavir to 600 mg every 8 hours should be considered when administering itraconazole or ketoconazole concurrently (see section 4.5).
Croatian: Pri istodobnoj primjeni itrakonazola ili ketokonazola treba razmotriti smanjenje doze indinavira na 600 mg svakih 8 sati (vidjeti dio 4.5).
English: Inhibition of CYP3A4 by both CRIXIVAN and ritonavir could result in elevated plasma concentrations of these medicines, potentially causing serious or life-threatening reactions (see section 4.5).
Croatian: Inhibicija CYP3A4 koju uzrokuju i CRIXIVAN i ritonavir može dovesti do povišenih koncentracija navedenih lijekova u plazmi i tako potencijalno izazvati ozbiljne ili po život opasne reakcije (vidjeti dio 4.5).
English: Zidovudine/Lamivudine 200/150 mg TID (Indinavir 800 mg TID)
Croatian: Zidovudin/lamivudin 200/150 mg TID (indinavir 800 mg TID)
English: There are no interaction data available on the coadministration of indinavir/ritonavir and amprenavir.
Croatian: Nema dostupnih podataka o interakciji kod istodobne primjene indinavira/ritonavira i amprenavira.
English: Characteristics in patients Pharmacokinetics of indinavir do not appear to be affected by race.
Croatian: Čini se da rasna pripadnost ne utječe na farmakokinetiku indinavira.
English: The most commonly reported symptoms were gastro-intestinal (e.g., nausea, vomiting, diarrhoea) and renal (e.g., nephrolithiasis, flank pain, haematuria).
Croatian: Najčešće prijavljeni simptomi bili su povezani s probavnim sustavom (npr. mučnina, povraćanje, proljev) i bubrezima (npr. nefrolitijaza, bol u slabinama, hematurija).
English: • CRIXIVAN - one 400 mg capsules (400 mg) - taken twice a day.
Croatian: • CRIXIVAN - jedna kapsula od 400 mg (400 mg) - dvaput na dan.
English: Nephrolithiasis occurred in approximately 10 % of patients treated with the recommended (unboosted) dose of CRIXIVAN in a pooled analysis of controlled clinical trials (see also below table and in section 4.4).
Croatian: U analizi objedinjenih podataka iz kontroliranih kliničkih ispitivanja nefrolitijaza se javila u otprilike 10% bolesnika liječenih preporučenom (nepojačanom) dozom lijeka CRIXIVAN (vidjeti i tablicu u nastavku teksta i dio 4.4).
English: Rosuvastatin AUC  2.08-fold Rosuvastatin Cmax  4.66-fold (Mechanism unknown)
Croatian: Ispitivanje interakcije s lopinavirom/ritonavirom + rosuvastatinom: AUC rosuvastatina  2,08 puta Cmax rosuvastatina  4,66 puta (mehanizam nije poznat)
English: ANTIDEPRESSANTS Trazodone 50 mg SD Ritonavir 200 mg BID
Croatian: Trazodon 50 mg SD Ritonavir 200 mg BID
English: Sixty-two patients completed the study to week 96.
Croatian: Ispitivanje u trajanju 96 tjedana su dovršila 62 bolesnika.
English: Amlodipine 5 mg QD (Indinavir/ritonavir 800/100 BID)
Croatian: Amlodipin 5 mg QD (indinavir/ritonavir 800/100 BID)
English: • Two 400 mg capsules (800 mg) - taken three times a day (every 8 hours).
Croatian: • dvije kapsule od 400 mg (800 mg) - triput na dan (svakih 8 sati).
English: Amlodipine AUC0-24hr:  80 % Indinavir/ritonavir AUCs: 
Croatian: AUC0-24h amlodipina:  80% AUC indinavira/ritonavira: 
English: The crystals have not been associated with medicinal product -induced renal injury.
Croatian: Kristali se ne povezuju s oštećenjem bubrega prouzročenim primjenom lijeka.
English: Dose reduction of CRIXIVAN to 600 mg every 8 hours should be considered.
Croatian: Treba razmotriti smanjenje doze lijeka CRIXIVAN na 600 mg svakih 8 sati.
English: • allergic reactions - signs include itchy skin, redness of the skin, ‘wheals' or ‘hives', swelling of the face, lips, tongue or throat and difficulty breathing.
Croatian: • alergijske reakcije - znakovi uključuju svrbež kože, crvenilo kože, koprivnjaču, oticanje lica,
English: CALCIUM CHANNEL BLOCKERS Diltiazem 120 mg QD (Indinavir/ritonavir 800/100 BID)
Croatian: BLOKATORI KALCIJEVIH KANALA Diltiazem 120 mg QD (indinavir/ritonavir 800/100 BID)
English: • CRIXIVAN - two 200 mg capsules (400 mg) - taken twice a day.
Croatian: • CRIXIVAN - dvije kapsule od 200 mg (400 mg) - dvaput na dan.
English: ANTI-INFECTIVES Antiretrovirals Amprenavir
Croatian: Antiretrovirusni lijekovi Amprenavir
English: EU/1/96/024/001 180 hard capsules EU/1/96/024/002 270 hard capsules EU/1/96/024/003 360 hard capsules
Croatian: EU/1/96/024/001 180 tvrdih kapsula EU/1/96/024/002 270 tvrdih kapsula EU/1/96/024/003 360 tvrdih kapsula
English: Not known* new onset diabetes mellitus or hyperglycaemia, or exacerbation of pre-existing diabetes mellitus, hypertriglyceridaemia, hypercholesterolaemia.
Croatian: Poremećaji metabolizma i prehrane nepoznato* novonastala šećerna bolest ili hiperglikemija ili egzacerbacija postojeće šećerne bolesti, hipertrigliceridemija, hiperkolesterolemija
English: • dexamethasone - used to stop swelling (inflammation)
Croatian: • deksametazon - koristi se za zaustavljanje oticanja (upale)
English: • The capsules are printed with printing ink containing indigo carmine (E 132).
Croatian: • Oznaka na kapsuli otisnuta je tintom za označavanje koja sadrži boju indigo karmin (E132).
English: Safety in patients with impaired renal function has not been studied; however, less than 20 % of indinavir is excreted in the urine as unchanged medicinal product or metabolites (see section 4.4).
Croatian: Nije ispitivana sigurnost primjene u bolesnika s oštećenom funkcijom bubrega, međutim, manje od 20% indinavira se izlučuje mokraćom u neizmijenjenom obliku ili u obliku metabolita (vidjeti dio 4.4).
English: Pharmacokinetic analysis in one study was performed on nineteen of the patients, with a median (range) indinavir AUC 0-12hr, Cmax, and Cmin of 25,421 nM*h (21,489 - 36,236 nM*h), 5,758 nM (5,056 - 6,742 nM) and 239 (169 - 421 nM), respectively.
Croatian: U jednom je ispitivanju provedena farmakokinetička analiza u 19 bolesnika, pri čemu je medijan (raspon) vrijednosti farmakokinetičkih parametara indinavira bio sljedeći: AUC 0-12h 25 421 nM*h (21 489 - 36 236 nM*h), Cmax 5758 nM (5056 - 6742 nM), a Cmin 239 (169 - 421 nM).
English: An increase in hepatic weight occurred in rats treated with indinavir at doses  40 mg/kg/day and was accompanied by hepatocellular hypertrophy at doses  320 mg/kg/day.
Croatian: U štakora koji su primali doze indinavira ≥ 40 mg/kg na dan primijećen je porast težine jetre koji je kod primjene doza ≥ 320 mg/kg na dan bio popraćen hipertrofijom jetrenih stanica.
English: In another study, at week 16, the proportion of patients with plasma viral RNA below 400 copies/mL was 59 %; the mean increase in CD4 cell counts was 73 cells/mm
Croatian: U drugom je ispitivanju u 16. tjednu udio bolesnika s vrijednošću virusne RNK u plazmi manjom od 400 kopija/ml bio 59%; srednje povećanje broja CD4 stanica bilo je 73 stanice/mm
English: Indinavir with or without ritonavir should not be administered concurrently with medicinal products with narrow therapeutic windows and which are substrates of CYP3A4.
Croatian: Indinavir se u kombinaciji s ritonavirom ili bez njega ne smije primjenjivati istodobno s lijekovima koji imaju uzak terapijski raspon i koji su supstrati za CYP3A4.
English: Data from published studies suggest that CRIXIVAN 400 mg in combination with ritonavir 100 mg, both administered orally twice daily, may be an alternative dosing regimen.
Croatian: Podaci iz objavljenih ispitivanja pokazuju da kombinacija lijeka CRIXIVAN u dozi od 400 mg i ritonavira u dozi od 100 mg, primijenjena peroralno dvaput na dan, može poslužiti kao alternativni režim doziranja.
English: Safety in patients with impaired renal function has not been studied; however, less than 20 % of indinavir is excreted in the urine as unchanged medicinal product or metabolites (see section 4.2).
Croatian: Nije ispitivana sigurnost primjene u bolesnika s oštećenom funkcijom bubrega, međutim, manje od 20% indinavira se izlučuje kroz mokraću u neizmijenjenu obliku ili u obliku metabolita (vidjeti dio 4.2).
English: Cyclosporine A dose adjustments should be made according to measured cyclosporine A trough blood levels.
Croatian: A treba prilagoditi izmjerenim vrijednostima ciklosporina A u krvi.
English: The combination of rifampicin and CRIXIVAN with concomitant low-dose ritonavir is contraindicated (see section 4.3).
Croatian: Kombinacija rifampicina i lijeka CRIXIVAN uz istodobnu primjenu niske doze ritonavira je kontraindicirana (vidjeti dio 4.3).
English: Not studied, combined administration may result in increased warfarin levels.
Croatian: Nije ispitivano, kombinirana primjena može dovesti do povišenih koncentracija varfarina.
English: EU/1/96/024/004 90 hard capsules EU/1/96/024/005 180 hard capsules
Croatian: EU/1/96/024/004 90 tvrdih kapsula EU/1/96/024/005 180 tvrdih kapsula
English: Caution should be used with coadministration of CRIXIVAN and parenteral midazolam.
Croatian: Nužan je oprez pri istodobnoj primjeni lijeka CRIXIVAN i parenteralnog midazolama.
English: ANTICONVULSANTS Carbamazepine, phenobarbital phenytoin
Croatian: Karbamazepin, fenobarbital, fenitoin
English: • bone problems - signs include stiff joints, aches and pains, especially of the hip and difficulty moving.
Croatian: • tegobe s kostima - znakovi uključuju ukočene zglobove, bolove posebno u kuku te otežano kretanje.
English: HISTAMINE H2 ANTAGONIST Cimetidine 600 mg BID (Indinavir 400 mg SD)
Croatian: ANTAGONISTI HISTAMINSKIH H2 RECEPTORA Cimetidin 600 mg BID (indinavir 400 mg SD)
English: CALCIUM CHANNEL BLOCKERS Dihydropyridine: e.g., felodipine, nifedipine, nicardipine
Croatian: Dihidropiridini: npr. felodipin, nifedipin, nikardipin
English: CRIXIVAN with or without ritonavir should not be administered concurrently with amiodarone, terfenadine, cisapride, astemizole, quetiapine, alprazolam, triazolam, midazolam administered orally (for caution on parenterally administered midazolam, see section 4.5), pimozide, ergot derivatives, simvastatin or lovastatin (see section 4.4).
Croatian: CRIXIVAN se u kombinaciji s ritonavirom ili bez njega ne smije primjenjivati istodobno s amiodaronom, terfenadinom, cisapridom, astemizolom, kvetiapinom, alprazolamom, triazolamom, midazolamom primijenjenim peroralno (za mjere opreza pri parenteralnoj primjeni midazolama vidjeti dio 4.5), pimozidom, derivatima ergota, simvastatinom ili lovastatinom (vidjeti dio 4.4).
English: Interactions and dose recommendations with other medical products - UNBOOSTED INDINAVIR
Croatian: Tablica 1. Interakcije i preporučene doze kod primjene s drugim lijekovima - SAMO INDINAVIR
English: • Four 200 mg capsules (800 mg) - taken three times a day (every 8 hours).
Croatian: • četiri kapsule od 200 mg (800 mg) - triput na dan (svakih 8 sati).
English: Concurrent use of indinavir with herbal preparations containing St John's wort (Hypericum perforatum) is contraindicated (see section 4.5).
Croatian: Kontraindicirana je istodobna primjena indinavira s biljnim pripravcima koji sadrže gospinu travu (Hypericum perforatum) (vidjeti dio 4.5).
English: • feeling dizzy, weak or tired.
Croatian: • omaglica, slabost ili umor.
English: Indinavir levels may increase on stopping St. John's wort, and the dose of CRIXIVAN may need adjusting.
Croatian: Nakon prekida primjene gospine trave može doći do povišenja koncentracije indinavira pa će možda biti potrebno prilagoditi dozu lijeka CRIXIVAN.
English: What CRIXIVAN is used for
Croatian: Za što se koristi CRIXIVAN
English: In one study, at week 24, the proportion of patients with plasma viral RNA below 400 copies/mL was 60 %; the mean increase in CD4 cell counts was 242 cells/mm
Croatian: U jednom je ispitivanju u 24. tjednu udio bolesnika s vrijednošću virusne RNK u plazmi manjom od 400 kopija/ml bio 60%; srednje povećanje broja CD4 stanica bilo je 242 stanice/mm
English: 3 years for HDPE bottles containing 90 and 180 hard capsules.
Croatian: 3 godine za bočice od polietilena visoke gustoće s 90 i 180 tvrdih kapsula.
English: Norethindrone AUC: ↑ 26 % Norethindrone Cmin: ↑ 44 %
Croatian: AUC noretindrona: ↑ 26% Cmin noretindrona: ↑ 44%
English: Caution should be used with coadministration of CRIXIVAN with ritonavir and parenteral midazolam.
Croatian: Nužan je oprez pri istodobnoj primjeni lijeka CRIXIVAN s ritonavirom i parenteralnog midazolama.
English: Asymptomatic pyuria of unknown etiology was noted in 10.9 % (6/55) of paediatric patients who received CRIXIVAN.
Croatian: U 10,9% (6/55) pedijatrijskih bolesnika koji su primali CRIXIVAN zabilježena je asimptomatska piurija nepoznate etiologije.
English: nephrolithiasis, in some cases with renal insufficiency or acute renal failure; pyelonephritis, interstitial nephritis, sometimes associated with indinavir crystal deposits.
Croatian: hematurija, proteinurija, kristalurija nefrolitijaza, dizurija nefrolitijaza, u nekim slučajevima praćena bubrežnom insuficijencijom ili akutnim zatajenjem bubrega, pijelonefritis, intersticijski nefritis ponekad povezan s taloženjem kristala indinavira.
English: Eighty antiretroviral naïve patients were entered into a third published study.
Croatian: U trećem objavljenom ispitivanju sudjelovalo je 80 bolesnika koji prethodno nisu bili liječeni antiretrovirusnim lijekovima.
English: Viral load remained < 200 copies/mL for 48 weeks in all patients.
Croatian: Virusno se opterećenje u svih bolesnika tijekom 48 tjedana zadržalo na vrijednosti od < 200 kopija/ml.
English: ANTIARRHYTHMICS Quinidine 200 mg SD (Indinavir 400 mg SD)
Croatian: ANTIARITMICI Kinidin 200 mg SD (indinavir 400 mg SD)
English: Vardenafil AUC: ↑ 16-fold
Croatian: AUC vardenafila: ↑ 16 puta
English: The following adverse reactions have been reported during clinical studies in adults and/or postmarketing use for CRIXIVAN monotherapy and/or CRIXIVAN with combination antiretroviral therapy (CART).
Croatian: Tijekom kliničkih ispitivanja u odraslih i/ili nakon stavljanja u promet lijeka CRIXIVAN u monoterapiji i/ili u sklopu kombiniranog antivirusnog liječenja prijavljene su sljedeće nuspojave.
English: ANTIHISTAMINES Fexofenadine
Croatian: ANTIHISTAMINICI Feksofenadin
English: Indinavir AUC: ↓ 20 % Indinavir Cmin: ↑ 29 % (Relative to Indinavir 800 mg TID alone) Indinavir AUC ↓ 56 % Indinavir Cmin ↓ 27 % (Relative to Indinavir 800 mg TID alone)
Croatian: AUC indinavira: ↓ 20% Cmin indinavira: ↑ 29% (u odnosu na primjenu samo indinavira u dozi od 800 mg TID) AUC indinavira ↓ 56% Cmin indinavira ↓ 27% (u odnosu na primjenu samo indinavira u dozi od 800 mg TID)
English: Caution is warranted and therapeutic concentration monitoring is recommended for quinidine when coadministered with CRIXIVAN.
Croatian: Kod istodobne primjene kinidina i lijeka CRIXIVAN potreban je oprez, a preporučuje se i praćenje terapijskih koncentracija kinidina.
English: Indinavir AUC: 25 % Indinavir Cmin ↓ 50 % (Relative to Indinavir/ritonavir 800/100 BID alone)
Croatian: AUC indinavira: 25% Cmin indinavira ↓ 50% (u odnosu na primjenu samo indinavira/ritonavira u dozi od 800/100 BID)
English: How to store CRIXIVAN
Croatian: Kako čuvati CRIXIVAN
English: Zidovudine 200 mg TID (Indinavir 1,000 mg TID)
Croatian: Zidovudin 200 mg TID (indinavir 1000 mg TID)
English: ORAL CONTRACEPTIVES Norethindrone/ethinyl estradiol 1/35 1 mcg QD (Indinavir 800 mg TID)
Croatian: Noretindron/etinilestradiol 1/35 1 µg QD (indinavir 800 mg TID)
English: Interaction with indinavir/ritonavir not studied
Croatian: Interakcija s indinavirom/ritonavirom nije ispitivana.
English: Herbal preparations containing St. John's wort are contraindicated with Crixivan.
Croatian: Primjena biljnih pripravaka koji sadrže gospinu travu i lijeka CRIXIVAN je kontraindicirana.
English: • The capsules are printed with printing ink containing titanium dioxide (E 171), indigo carmine (E 132) and iron oxide (E 172).
Croatian: • Oznaka na kapsuli otisnuta je tintom za označavanje koja sadrži titanijev dioksid (E171), boju indigo karmin (E132) i željezov oksid (E172).
English: At week 60, the proportion of patients with plasma viral RNA below 400 copies/mL was 59 %.
Croatian: 60. je tjednu udio bolesnika s vrijednošću virusne RNK u plazmi manjom od 400 kopija/ml iznosio 59%.
English: CRIXIVAN 400 mg hard capsules are supplied in HDPE bottles with a polypropylene cap and a foil seal containing 90 or 180 capsules.
Croatian: CRIXIVAN 400 mg tvrde kapsule dolaze u bočici od polietilena visoke gustoće s polipropilenskim zatvaračem i zaštitnom folijom koja sadrži 90 ili 180 kapsula.
English: CRIXIVAN and oral midazolam should not be coadministered (see section 4.3).
Croatian: CRIXIVAN i peroralni midazolam ne smiju se primjenjivati istodobno (vidjeti dio 4.3).
English: ANTIASTHMATIC Theophylline 250 mg SD (Indinavir 800 mg TID)
Croatian: ANTIASTMATICI Teofilin 250 mg SD (indinavir 800 mg TID)
English: Not known* anaphylactoid reactions
Croatian: Poremećaji imunološkog sustava nepoznato* anafilaktoidne reakcije
English: CRIXIVAN 200 mg hard capsules are supplied in HDPE bottles with a polypropylene cap and a foil seal containing 180, 270 or 360 capsules.
Croatian: CRIXIVAN 200 mg tvrde kapsule dolaze u bočici od polietilena visoke gustoće s polipropilenskim zatvaračem i zaštitnom folijom koja sadrži 180, 270 ili 360 kapsula.
English: Itraconazole 200 mg BID (Indinavir 600 mg TID)
Croatian: Itrakonazol 200 mg BID (indinavir 600 mg TID)
English: The following side effects have also been reported since the medicine has been used.
Croatian: Nuspojave su prijavljivane i nakon stavljanja lijeka u promet*.
English: In addition, indinavir with ritonavir must not be administered with alfuzosin, meperidine, piroxicam, propoxyphene, bepridil, encainide, flecanide, propafenone, quinidine, fusidic acid, clozapine, clorazepate, diazepam, estazolam and flurazepam.
Croatian: Osim toga, indinavir i ritonavir se ne smiju primjenjivati s alfuzosinom, meperidinom, piroksikamom, propoksifenom, bepridilom, enkainidom, flekanidom, propafenonom, kvinidinom, fusidatnom kiselinom, klozapinom, klorazepatom, diazepamom, estazolamom i flurazepamom.
English: At steady state following a dose regimen of 800 mg/100 mg of indinavir/ritonavir every 12 hours with a low-fat meal, healthy volunteers in one study achieved geometric means: AUC0-12h 116,067 nM*h (90 % confidence interval = 101,680, 132,490), peak plasma concentrations 19,001 nM (90 % confidence interval = 17,538, 20,588), and plasma concentrations at 12 hours post dose 2,274 nM (90 % confidence interval = 1,701, 3,042).
Croatian: U stanju dinamičke ravnoteže nakon režima doziranja od 800 mg indinavira/100 mg ritonavira primijenjenih svakih 12 sati uz obrok siromašan mastima zdravi su dobrovoljci u jednome ispitivanju postigli sljedeće srednje geometrijske vrijednosti: AUC0-12h = 116 067 nM*h (90% interval pouzdanosti: 101 680, 132 490), vršne koncentracije u plazmi = 19 001 nM (90% interval pouzdanosti: 17 538, 20 588) i koncentracije u plazmi 12 sati nakon primjene doze = 2274 nM (90% interval pouzdanosti: 1701, 3042).
English: Capsule shell: gelatin titanium dioxide (E 171) printing ink: indigo carmine (E 132).
Croatian: Ovojnica kapsule: želatina titanijev dioksid (E171) tinta za označavanje: indigo karmin (E132).
English: CRIXIVAN with ritonavir and oral midazolam should not be coadministered (see section 4.3).
Croatian: CRIXIVAN s ritonavirom i peroralni midazolam ne smiju se istodobno primjenjivati (vidjeti dio 4.3).
English: CRIXIVAN 200 mg - packs of 180, 270 and 360 capsules - Bottle label
Croatian: CRIXIVAN 200 mg - pakiranja sa 180, 270 i 360 kapsula - naljepnica bočice
English: Interaction with indinavir/ritonavir not studied Trazodone AUC:  2.4-fold An increase in the incidence in trazodonerelated adverse events was noted when coadministered with ritonavir.
Croatian: AUC trazodona:  2,4 puta Kod istodobne primjene s ritonavirom primijećeno je povećanje incidencije nuspojava povezanih s trazodonom.
English: At week 24, the proportion of patients with plasma viral RNA below 400 copies/mL was 60 %.
Croatian: U 24. tjednu je udio bolesnika s vrijednošću virusne RNK u plazmi manjom od 400 kopija/ml iznosio 60%.
English: Indinavir AUC and Cmin:  (Relative to Indinavir 400 mg QID alone) Sulphamethoxazole AUC and Cmin: 
Croatian: AUC i Cmin indinavira:  (u odnosu na primjenu samo indinavira u dozi od 400 mg QID) AUC i Cmin sulfametoksazola: 
English: Coadministration of CRIXIVAN with tadalafil is likely to result in an increase of tadalafil by competitive inhibition of metabolism.
Croatian: Istodobna primjena lijeka CRIXIVAN s tadalafilom vjerojatno će dovesti do povećanja koncentracije tadalafila zbog kompetitivne inhibicije metabolizma.
English: Following a dose regimen of 800 mg every 8 hours, measured peak plasma concentrations (Cmax) after morning, afternoon and evening doses were 15,550 nM, 8,720 nM and 8,880 nM, respectively.
Croatian: Nakon režima doziranja od 800 mg svakih 8 sati izmjerena vršna koncentracija u plazmi (Cmax) nakon jutarnje doze bila je 15 550 nM, nakon popodnevne doze 8720 nM, a nakon večernje doze 8880 nM. Odgovarajuće koncentracije u plazmi 8 sati nakon primjene doze iznosile su 220 nM (jutarnja doza), 210 nM (popodnevna doza) i 370 nM (večernja doza).
English: CRIXIVAN 400 mg - packs of 90 and 180 capsules - Bottle label
Croatian: CRIXIVAN 400 mg - pakiranja sa 90 i 180 kapsula - naljepnica bočice
English: Saquinavir AUC:  500 % Saquinavir Cmin:  190 % (Relative to saquinavir 600 mg SD (hard gel formulation) alone)
Croatian: AUC sakvinavira:  500% Cmin sakvinavira:  190% (u odnosu na primjenu samo sakvinavira (tvrda želatinozna kapsula) u dozi od 600 mg SD)
English: CRIXIVAN with or without ritonavir should not be administered concurrently with amiodarone, terfenadine, cisapride, astemizole, quetiapine, alprazolam, triazolam, midazolam administered orally (for caution on parenterally administered midazolam, see Table 1 and 2 below), pimozide, ergot derivatives, simvastatin or lovastatin.
Croatian: CRIXIVAN se u kombinaciji s ritonavirom ili bez njega ne smije primjenjivati istodobno s amiodaronom, terfenadinom, cisapridom, astemizolom, kvetiapinom, alprazolamom, triazolamom, midazolamom primijenjenim peroralno (za mjere opreza pri parenteralnoj primjeni midazolama vidjeti Tablice 1 i 2 u nastavku), pimozidom, derivatima ergota, simvastatinom ili lovastatinom.
English: • indigestion or diarrhoea
Croatian: • probavne tegobe ili proljev
English: Indinavir AUC and Cmin: ↔ (Relative to Indinavir 800 mg TID alone) Isoniazid AUC and Cmin: 
Croatian: AUC i Cmin indinavira: ↔ (u odnosu na primjenu samo indinavira u dozi od 800 mg TID) AUC i Cmin izoniazida: 
English: ANALGESICS Methadone 20-60 mg QD (Indinavir 800 mg TID)
Croatian: ANALGETICI Metadon 20-60 mg QD (indinavir 800 mg TID)
English: Interaction with indinavir/ritonavir not studied Ritonavir induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Croatian: Ritonavir inducira oksidaciju pomoću CYP2C9 i glukuronidaciju pa se očekuje smanjenje koncentracija antikonvulziva u plazmi.
English: Indinavir AUC and Cmin: ↔ (Relative to Indinavir 800 mg TID alone*)
Croatian: AUC i Cmin indinavira: ↔ (u odnosu na primjenu samo indinavira u dozi od 800 mg TID*)
English: Indinavir AUC24hr: 178 % Indinavir Cmin:11-fold; (Relative to Indinavir 800 mg TID alone*) Ritonavir AUC:  72 % Ritonavir Cmin:  62 %
Croatian: AUC24hr indinavira: 178% Cmin indinavira:11 puta; (u odnosu na primjenu samo indinavira u dozi od 800 mg TID*) AUC ritonavira:  72% Cmin ritonavira:  62%
English: Indinavir AUC: ↓ 24 % Indinavir Cmin:  (Relative to Indinavir 1,000 mg TID alone)
Croatian: AUC indinavira: ↓ 24% Cmin indinavira:  (u odnosu na primjenu samo indinavira u dozi od 1000 mg TID)
English: Interaction not studied  dexamethasone exposure expected (CYP3A inhibition).
Croatian: Očekuje se  izloženosti deksametazonu (inhibicija CYP3A).
English: You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects you can help provide more information on the safety of this medicine.
Croatian: Nuspojave možete prijaviti izravno putem nacionalnog sustava za prijavu nuspojava u Dodatku V.
English: Stavudine 40 mg BID (Indinavir 800 mg TID)
Croatian: Stavudin 40 mg BID (indinavir 800 mg TID)
English: ANALGESICS Fentanyl
Croatian: ANALGETICI Fentanil