FrancophonIA/ELRC3.0 huggingface dataset:
English: Had treatment with any medicine containing infliximab before
Slovenian: Predhodno ste se že zdravili s katerimkoli zdravilom, ki vsebuje infliksimab
English: • Some patients receiving infliximab have developed symptoms of an immune system disorder called lupus.
Slovenian: • Pri nekaterih bolnikih, ki prejemajo infliksimab, so se pojavili simptomi motnje v delovanju imunskega sistema, ki ji pravimo lupus.
English: Patients who develop a new infection while undergoing treatment with infliximab, should be monitored closely and undergo a complete diagnostic evaluation.
Slovenian: Tiste bolnike, pri katerih se med zdravljenjem z infliksimabom pojavi nova okužba, je treba natančno spremljati in pri njih opraviti celotni diagnostični postopek.
English: Table 10 Summary of PASI response, PGA response and percent of patients with all nails cleared at Weeks 10, 24 and 50.
Slovenian: Preglednica 10 Povzetek odzivov PASI,vrednosti PGA in delež bolnikov z nohti brez psoriatičnih sprememb v 10., 24. in 50. tednu.
English: Of these 108 patients, 27 were treated with the recommended dosage of infliximab 5 mg/kg.
Slovenian: 27 od teh 108 bolnikov so zdravili s priporočenim odmerkom infliksimaba 5 mg/kg.
English: Table 6 Percent of patients achieving corticosteroid-free clinical remission at Week 26, SONIC AZA Monotherapy
Slovenian: Preglednica 6 Odstotek bolnikov, ki so dosegli klinično remisijo brez jemanja kortikosteroidov v 26. tednu, SONIC
English: • In case you have received Inflectra while you were pregnant, it is important that you inform your baby's doctor about it before your baby receives any vaccine.
Slovenian: • Če ste med nosečnostjo prejeli zdravilo Inflectra, je pomembno, da o tem obvestite zdravnika vašega dojenčka, preden dojenček prejme katerokoli cepivo.
English: Ask your doctor to record the type and date of last screening(s) for tuberculosis (TB) below: Test
Slovenian: Zdravnika prosite, naj spodaj zabeleži vrsto in datume zadnjih presejalnih testov za tuberkulozo (TBC):
English: Sustained remission(in remission at both week 8 and week 30)
Slovenian: Trajnejša remisija (remisija tako v 8. tednu kot v
English: If a patient develops symptoms suggestive of a lupus-like syndrome following treatment with infliximab and is positive for antibodies against double-stranded DNA, further treatment with infliximab must not be given (see section 4.8).
Slovenian: Če se po zdravljenju z infliksimabom pri bolniku pojavijo simptomi, ki kažejo na lupusu podoben sindrom, in je bolnik pozitiven na protitelesa proti dvojnoverižni DNA, ne sme več prejeti infliksimaba (glejte poglavje 4.8).
English: This patient reminder card contains important safety information that you need to be aware of before and during treatment with Inflectra.
Slovenian: Ta opozorilna kartica za bolnika vsebuje pomembne informacije o varnosti, s katerimi morate biti seznanjeni, preden prejmete zdravilo Inflectra in med zdravljenjem s tem zdravilom.
English: Further treatment with infliximab must not be given if a patient develops a serious infection or sepsis.
Slovenian: Bolnika ne smete več zdraviti z infliksimabom, če dobi resno okužbo ali sepso.
English: • It is very important that you tell your doctor if you have ever had tuberculosis (TB), or if you have been in close contact with someone who has had TB.
Slovenian: • Zelo pomembno je, da zdravniku poveste, če ste kdaj imeli tuberkulozo ali ste bili v tesnem stiku z bolnikom s tuberkulozo.
English: In patients who have several or significant risk factors for tuberculosis and have a negative test for latent tuberculosis, antituberculosis therapy should be considered before the initiation of infliximab.
Slovenian: Pri bolnikih, ki imajo več dejavnikov tveganja oziroma pomembne dejavnike tveganja za tuberkulozo in pri katerih je bil test na latentno tuberkulozo negativen, premislite, ali bi bilo treba pri njih pred uvedbo infliksimaba najprej zdraviti tuberkulozo.
English: Inflectra infusions should be administered by qualified healthcare professionals trained to detect any infusion-related issues.
Slovenian: Infuzije zdravila Inflectra morajo bolniku dajati kvalificirani zdravstveni delavci, ki so usposobljeni za ugotavljanje morebitnih težav pri infundiranju zdravil.
English: Immune system disorder
Slovenian: Motnja v delovanju imunskega sistema
English: If these medicines do not work well enough, you will be given Inflectra which you will take with another medicine called methotrexate to:
Slovenian: Če ta zdravila ne bodo dovolj dobro delovala, boste prejeli zdravilo Inflectra skupaj z zdravilom, imenovanim metotreksat, za:
English: Before starting treatment with infliximab, all patients must be evaluated for both active and inactive (‘latent') tuberculosis.
Slovenian: Pred začetkom zdravljenja z infliksimabom morate vse bolnike pregledati in preiskati, da ugotovite morebitno aktivno ali neaktivno (latentno) tuberkulozo.
English: Significant improvements from baseline were demonstrated in DLQI (p<0.001) and the physical and mental component scores of the SF 36 (p<0.001 for each component comparison).
Slovenian: Pri oceni po DLQI (p < 0,001) so dokazali bistveno izboljšanje glede na začetne vrednosti, pa tudi glede ocen telesne in duševne komponente po SF 36 (p < 0,001 za primerjavo vsake komponente).
English: Infusion reactions and hypersensitivity
Slovenian: Z infuzijo povezane reakcije in preobčutljivost
English: ACR 20 response* ACR 50 response* ACR 70 response* PASI response (% of patients)b
Slovenian: Odziv ACR 20* 5(10 %) Odziv ACR 50* 0(0 %) Odziv ACR 70* 0(0 %) Odziv PASI (% bolnikov)
English: Children may receive some vaccines during treatment with Inflectra but should not receive live vaccines while using Inflectra.
Slovenian: Otroci lahko med zdravljenjem z zdravilom Inflectra prejmejo nekatera cepiva, vendar med uporabo zdravila Inflectra ne smejo prejeti živih cepiv.
English: • Tell your doctor if you think you might be at risk of contracting hepatitis B.
Slovenian: • Povejte svojemu zdravniku, če mislite, da pri vas obstaja možnost, da bi se okužili s hepatitisom B.
English: • Re-administration: Infusion of 5 mg/kg if signs and symptoms of the disease recur followed by infusions of 5 mg/kg every 8 weeks (see ‘Re-administration' below and section 4.4).
Slovenian: • Ponovna uporaba zdravila: Infuzija v odmerku 5 mg/kg, če se ponovijo znaki in simptomi bolezni, čemur naj sledijo infuzije v odmerku 5 mg/kg na vsakih 8 tednov (glejte “Ponovna uporaba zdravila” spodaj in poglavje 4.4).
English: • you are allergic to proteins that come from mice,
Slovenian: • če ste alergični na glodalske proteine,
English: • Children should receive recommended vaccinations before starting Inflectra treatment.
Slovenian: • Otroci morajo prejeti priporočena cepljenja, preden se začnejo zdraviti z zdravilom Inflectra.
English: During Inflectra treatment, other concomitant therapies, e.g. corticosteroids and immunosuppressants should be optimised.
Slovenian: Med zdravljenjem z zdravilom Inflectra je treba optimizirati druge sočasne terapije, npr. s kortikosteroidi in zdravili za zaviranje imunske odzivnosti.
English: Meningitis, opportunistic infections (such as invasive fungal infections [pneumocystosis, histoplasmosis, aspergillosis, coccidioidomycosis, cryptococcosis, blastomycosis], bacterial infections [atypical mycobacterial, listeriosis, salmonellosis], and viral infections [cytomegalovirus]), parasitic infections, hepatitis B reactivation.
Slovenian: meningitis, oportunistične okužbe (npr. invazivne glivične okužbe [pnevmocistoza, histoplazmoza, aspergiloza, kokcidioidomikoza, kriptokokoza, blastomikoza], bakterijske okužbe [okužbe z atipičnimi mikobakterijami, listerioza, salmoneloza] in virusne okužbe [s citomegalovirusom]), okužbe s paraziti, reaktivacija hepatitisa B
English: • Blood problems such as anaemia or low white blood cell count
Slovenian: • težave s krvjo, kot na primer anemija ali nizko število belih krvnih celic
English: * including bovine tuberculosis (disseminated BCG infection), see section 4.4
Slovenian: nenormalna vrednost faktorja komplementa * vključno z bovino tuberkulozo (razsejano okužbo BCG), glejte poglavje 4.4
English: Subjects randomised Percentage ACR improvement Mean ± SD
Slovenian: Odstotek izboljšanja ACR
English: • Tell your surgeon or dentist that you are having treatment with Inflectra by showing them your patient reminder card.
Slovenian: • Obvestite svojega kirurga ali zobozdravnika, da prejemate zdravilo Inflectra in mu pokažite svojo opozorilno kartico za bolnika.
English: Inflectra treatment is to be initiated and supervised by qualified physicians experienced in the diagnosis and treatment of rheumatoid arthritis, inflammatory bowel diseases, ankylosing spondylitis, psoriatic arthritis or psoriasis.
Slovenian: Zdravljenje z zdravilom Inflectra mora uvesti in nadzorovati kvalificiran zdravnik, ki je izkušen v diagnostiki in zdravljenju revmatoidnega artritisa, vnetnih bolezni črevesa, ankilozirajočega spondilitisa, psoriatičnega artritisa ali psoriaze.
English: • If you get any side effects, talk to your doctor.
Slovenian: • Če opazite katerikoli neželeni učinek, se posvetujte z zdravnikom.
English: • Chills, a build-up of fluid under the skin causing swelling
Slovenian: • mrzlica, kopičenje vode pod kožo, ki povzroča otekanje
English: • Infection due to a live vaccine because of a weakened immune system.
Slovenian: • okužba zaradi živega cepiva kot posledica oslabljenega imunskega sistema
English: Additionally, closure of all fistulae was achieved in 55% of infliximab-treated patients compared with 13% of placebo-treated patients (p=0.001).
Slovenian: Dodatno so pri 55 % bolnikov zdravljenih z infliksimabom dosegli zapiranje vseh fistul, v primerjavi s 13 % bolnikov, ki so prejemali placebo (p = 0,001).
English: • Talk to your doctor if you recently have had or are due to have a vaccine.
Slovenian: • Obvestite svojega zdravnika, če ste bili pred kratkim cepljeni ali boste cepljeni.
English: • Possible signs of cancer including but not limited to swelling of lymph nodes, weight loss, fever, unusual skin nodules, changes in moles or skin colouring, or unusual vaginal bleeding.
Slovenian: • možni znaki raka, vključno z, vendar ne omejeno na otekanje bezgavk, izgubo telesne mase, zvišano telesno temperaturo, nenavadnimi kožnimi vozliči, spremembami kožnih znamenj ali barve kože ali nenavadnimi krvavitvami iz nožnice;
English: Patients with fistulising Crohn's disease with acute suppurative fistulas must not initiate infliximab therapy until a source for possible infection, specifically abscess, has been excluded (see section 4.3).
Slovenian: Pri bolnikih s fistulirajočo Crohnovo boleznijo z akutnimi gnojnimi fistulami ne smete uvesti terapije z infliksimabom, dokler ne izključite možnosti, da obstaja nekje vir okužbe, na primer absces (glejte poglavje 4.3).
English: Type 1 glass vial with a (butyl) rubber stopper and an aluminium seal with a flip-off button.
Slovenian: Viala iz stekla tipa 1 z (butilnim) gumijastim zamaškom in aluminijastim tesnilom s »flip-off« sistemom.
English: More signs of allergic side effects that may happen up to 12 days after your injection include pain in the muscles, fever, joint or jaw pain, sore throat or headache.
Slovenian: Dodatni znaki z alergijo povezanih učinkov, ki se lahko pojavijo do 12 dni po prejemu injekcije, so bolečine v mišicah, zvišana telesna temperatura, bolečine v sklepih ali v čeljusti, vnetje žrela ali glavobol;
English: Inflectra contains the active substance infliximab, which is of human and mouse origin.
Slovenian: Zdravilo Inflectra vsebuje učinkovino infliksimab, ki je človeško-glodalskega izvora.
English: Lymphoma, non-Hodgkin's lymphoma, Hodgkin's disease, leukaemia, melanoma, cervical cancer.
Slovenian: limfom, ne-Hodgkinov limfom, Hodgkinova bolezen, levkemija, melanom, rak materničnega vratu neznana pogostnost:
English: Inflectra must be given concomitantly with methotrexate.
Slovenian: Zdravilo Inflectra morate uporabljati sočasno z metotreksatom.
English: By week 26, twenty weeks after the last induction dose, 30% of patients in the 5 mg/kg group and 13.8% of patients in the 3 mg/kg group were PASI 75 responders.
Slovenian: Do 26. tedna, tj. dvajset tednov po zadnjem uvodnem odmerku, je 30 % bolnikov iz skupine, ki je prejemala 5 mg/kg, in 13,8 % bolnikov iz skupine, ki je prejemala 3 mg/kg, imelo odziv PASI 75.
English: • Tell your doctor before you are given Inflectra if you have or have ever had lymphoma (a type of blood cancer) or any other cancer.
Slovenian: • Preden začnete uporabljati zdravilo Inflectra, povejte svojemu zdravniku, če imate ali ste imeli kdaj v preteklosti limfom (vrsta krvnega raka) oziroma katerokoli drugo vrsto raka.
English: In clinical studies with infliximab in which 5,780 patients were treated, representing 5,494 patient years, 5 cases of lymphomas and 26 non-lymphoma malignancies were detected as compared with no lymphomas and 1 non-lymphoma malignancy in 1,600 placebo-treated patients representing 941 patient years.
Slovenian: V kliničnih študijah z infliksimabom, v katerih je bilo zdravljenih 5.780 bolnikov, to pomeni skupaj 5.494 bolnikov-let, so odkrili 5 primerov limfoma in 26 nelimfomskih rakavih bolezni, pri 1.600 s placebom zdravljenih bolnikih, to pomeni skupaj 941 bolnikov-let, pa nič limfomov in 1 nelimfomsko rakavo bolezen.
English: Continued therapy with a shortened interval should be carefully considered in those patients who show no evidence of additional therapeutic benefit after a change in dosing interval.
Slovenian: Nadaljevanje zdravljenja s skrajšanim razmikom je treba skrbno pretehtati pri tistih bolnikih, ki ne kažejo znakov dodatne klinične koristi po spremembi odmernega intervala.
English: At 54 weeks, 44.9% of patients in the combined infliximab treatment group were in clinical response compared to 19.8% in the placebo treatment group (p<0.001).
Slovenian: V 54. tednu je 44,9 % bolnikov v (združeni) skupini, ki se je zdravila z infliksimabom, kazalo klinični odziv, v primerjavi z 19,8 % v skupini, ki je prejemala placebo (p < 0,001).
English: • If your doctor feels that you are at risk for TB, you may be treated with medicines for TB before you are given Inflectra.
Slovenian: • Če zdravnik sumi, da je možno da imate tuberkulozo, vas bo lahko zdravil z zdravili za tuberkulozo, preden boste začeli zdravljenje z zdravilom Inflectra.
English: • treat active Crohn's disease,
Slovenian: • zdravljenje aktivne Chronove bolezni,
English: Do not dilute the reconstituted Inflectra solution with any other diluent.
Slovenian: Rekonstituirane raztopine zdravila Inflectra ne redčite z nobeno drugo tekočino.
English: For patients who have resided in or travelled to regions where invasive fungal infections such as histoplasmosis, coccidioidomycosis, or blastomycosis are endemic, the benefits and risks of infliximab treatment should be carefully considered before initiation of infliximab therapy.
Slovenian: Pri bolnikih, ki so živeli ali potovali v kraje, kjer so endemične invazivne glivične okužbe, kot so histoplazmoza, kokcidioidomikoza ali blastomikoza, je treba skrbno pretehtati koristi in tveganja zdravljenja z infliksimabom, preden bolniku uvedete to zdravilo.
English: The solution has to be gently swirled by rotating the vial to dissolve the powder.
Slovenian: Z vrtenjem viale rahlo premešajte raztopino, da se prašek raztopi.
English: EXPRESS Placebo → Infliximab 5 mg/kg (at week 24)
Slovenian: placebo → infliximab 5 mg/kg (24 teden)
English: There are no known side effects of having too much of Inflectra.
Slovenian: Ni poznanih neželenih učinkov zaradi prejetja prevelikega odmerka zdravila Inflectra.
English: The side effects that happened more in children were: low red blood cells (anaemia), blood in stool, low overall levels of white blood cells (leukopenia), redness or blushing (flushing), viral infections, low levels of white blood cells that fight infection (neutropenia), bone fracture, bacterial infection and allergic reactions of the breathing tract.
Slovenian: Pri otrocih so se pogosteje pojavili naslednji neželeni učinki: nizko število rdečih krvnih celic (anemija), kri v blatu, nizko skupno število belih krvnih celic (levkopenija), rdečina ali zardevanje, virusne okužbe, nizko število belih krvnih celic, ki se borijo proti okužbi (nevtropenija), zlom kosti, bakterijska okužba in alergijske reakcije v dihalih.
English: • That treatment with Inflectra may increase the risks of serious infections/sepsis, opportunistic infections, tuberculosis, hepatitis B reactivation, and BCG breakthrough in infants with in utero exposure to infliximab, and when to seek attention from a HCP
Slovenian: • navedbo, da lahko zdravljenje z zdravilom Inflectra poveča tveganje za resne okužbe/sepso, oportunistične okužbe, tuberkulozo, reaktivacijo hepatitisa B in okužbo z bacilom CalmetteGuerin (BCG) pri dojenčkih po in utero izpostavitvi ter kdaj poiskati pomoč zdravstvenega delavca;
English: Inflectra is a biosimilar medicinal product.
Slovenian: Zdravilo Inflectra je podobno biološko zdravilo.
English: • Signs of a nervous system problem (including eye problems) such as signs of a stroke (sudden numbness or weakness of your face, arm or leg, especially on one side of your body; sudden confusion, trouble speaking or understanding; trouble seeing in one or both eyes, trouble walking, dizziness, loss of balance or coordination or a severe headache), fits, tingling/numbness in any part of your body, or weakness in arms or legs, changes in eyesight such as double vision or other eye problems.
Slovenian: • znaki težav z živčevjem (vključno s težavami z očmi), na primer znaki možganske kapi (nenadna odrevenelost ali šibkost obraza, rok ali nog, predvsem na eni strani telesa; nenadna zmedenost, težave z govorom ali razumevanjem; težave z vidom na enem ali obeh očesih, težave s hojo, omotica, izguba ravnotežja ali koordinacije ali hud glavobol), epileptični napadi, mravljinci/občutek odrevenelosti v kateremkoli delu telesa ali šibkost rok ali nog, spremembe vida, na primer dvojni vid ali druge težave z očmi;
English: Table 7 Effects on response rate, data from ACCENT II (Week-14 responders) ACCENT II (Week-14 responders)
Slovenian: Preglednica 7 Učinki na stopnjo odziva; podatki iz študije ACCENT II (bolniki z odzivom v 14. tednu)
English: Inflectra is indicated for treatment of active and progressive psoriatic arthritis in adult patients when the response to previous DMARD therapy has been inadequate.
Slovenian: Zdravilo Inflectra je indicirano za zdravljenje aktivnega in napredujočega psoriatičnega artritisa pri odraslih bolnikih v primeru nezadostnega odziva na predhodno zdravljenje s protirevmatičnimi zdravili DMARD.
English: Limited experience from re-treatment following disease flare by a re-induction regimen suggests a higher incidence of infusion reactions, including serious ones, when compared to 8-weekly maintenance treatment (see section 4.8).
Slovenian: Omejene izkušnje s ponovnim zdravljenjem bolnikov zaradi novega izbruha bolezni, tj. izkušnje s ponovno uporabo uvodne sheme, so pokazale večjo incidenco z infuzijo povezanih reakcij, vključno z resnimi z infuzijo povezanimi reakcijami, v primerjavi z 8-tedenskim vzdrževalnim zdravljenjem (glejte poglavje 4.8).
English: • Your blood not supplying enough oxygen to your body, circulation problems such as narrowing of a blood vessel
Slovenian: • nezadostna oskrba telesa s kisikom preko krvi, motnje pretoka, kot na primer zožitev krvnih žil
English: Inflectra is not likely to affect your ability to drive or use tools or machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Zdravilo Inflectra verjetno ne vpliva na vašo sposobnost vožnje in upravljanja z orodji ali stroji.
English: A patient who requires surgery while on infliximab should be closely monitored for infections, and appropriate actions should be taken.
Slovenian: Bolnika, pri katerem je med zdravljenjem z infliksimabom potreben kirurški poseg, morate skrbno spremljati, da ugotovite morebitne okužbe, in uvesti ustrezne ukrepe.
English: Isolated cases of liver failure resulting in liver transplantation or death have occurred.
Slovenian: V posameznih primerih je prišlo do odpovedi jeter, ki je zahtevala transplantacijo jeter ali povzročila smrt.
English: • Tell your doctor if you have any abnormal skin openings (fistulae) before you are given Inflectra.
Slovenian: • Obvestite svojega zdravnika, če imate na koži nenormalne odprtine (fistule), preden začnete prejemati zdravilo Inflectra.
English: Inflectra is indicated for treatment of severe, active ankylosing spondylitis, in adult patients who have responded inadequately to conventional therapy.
Slovenian: Zdravilo Inflectra je indicirano za zdravljenje hudega aktivnega ankilozirajočega spondilitisa pri odraslih bolnikih, ki so se nezadostno odzvali na konvencionalno terapijo.
English: Brand name: Batch number:
Slovenian: Lastniško ime: Številka serije:
English: In most patients, infliximab could be detected in the serum for at least 8 weeks after the recommended single dose of 5 mg/kg for Crohn's disease and the rheumatoid arthritis maintenance dose of 3 mg/kg every 8 weeks.
Slovenian: Pri večini bolnikov so infliksimab našli v serumu še najmanj 8 tednov po priporočenem enkratnem odmerku za zdravljenje Crohnove bolezni 5 mg/kg, ali pri vzdrževalnem odmerku za zdravljenje revmatoidnega artritisa,3 mg/kg na vsakih 8 tednov.
English: Toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, furunculosis, linear IgA bullous dermatosis (LABD), acute generalised exanthematous pustulosis (AGEP), lichenoid reactions.
Slovenian: toksična epidermalna nekroliza, Stevens-Johnsonov sindrom, multiformni eritem, furunkuloza, linearna IgA bulozna dermatoza (LABD), akutna generalizirana eksantematozna pustuloza (AGEP - acute generalised exanthematous pustulosis), lihenoidne reakcije neznana pogostnost:
English: Infliximab is a chimeric human-murine monoclonal antibody that binds with high affinity to both soluble and transmembrane forms of TNFα but not to lymphotoxin α (TNFβ).
Slovenian: Infliksimab je himerno človeško-glodalsko monoklonsko protitelo, ki se z veliko afiniteto veže tako na topne kot na transmembranske oblike TNFα, ne pa tudi na limfotoksin α (TNFß).
English: c a control = All patients had active RA despite treatment with stable methotrexate doses for 6 months prior to enrolment and were to remain on stable doses throughout the study.
Slovenian: ± SD a Kontrolna skupina: Vsi bolniki so imeli aktivni revmatoidni artritis kljub zdravljenju s stalnimi odmerki metotreksata že 6 mesecev pred vključitvijo v študijo; te odmerke so prejemali še naprej ves čas študije.
English: Infliximab treatment reduced the rate of progression of peripheral joint damage compared with placebo treatment at the week 24 primary endpoint as measured by change from baseline in total modified vdH-S score (mean ± SD score was 0.82 ± 2.62 in the placebo group compared with -0.70 ± 2.53 in the infliximab group; p<0.001).
Slovenian: Zdravljenje z infliksimabom je zmanjšalo hitrost napredovanja okvare perifernih sklepov v primerjavi s placebom v 24. tednu kot primarni končni rezultat, merjeno kot sprememba celotne vrednosti modificiranega rezultata vdH-S glede na stanje na začetku študije (v skupini za placebo je znašala srednja vrednost ± SD 0,82 ± 2,62, v primerjavi z -0,70 ± 2,53 za skupino, ki je prejemala infliksimab; p < 0,001).
English: Following administration of 5 mg/kg infliximab every 8 weeks, the predicted median steady-state infliximab exposure (area under concentration-time curve at steady state, AUCss) in paediatric patients aged 6 years to 17 years was approximately 20% lower than the predicted median steady-state medicinal product exposure in adults.
Slovenian: Pri uporabi infliksimaba 5 mg/kg vsakih 8 tednov je bila napovedana mediana izpostavljenosti infliksimabu v stanju dinamičnega ravnovesja (površina pod krivuljo koncentracija-čas v stanju dinamičnega ravnovesja, AUCss) pri pediatričnih bolnikih, starih od 6 let do 17 let, približno 20 % nižja od napovedane mediane izpostavljenosti zdravilu v stanju dinamičnega ravnovesja pri odraslih.