FrancophonIA/ELRC3.0 huggingface dataset:
English: Over 58.9% and 22.3% of the psoriatic arthritis patients had enthesitis and dactylitis at baseline, respectively.
Danish: Over 58,9% og 22,3% af patienterne med psoriasisartrit havde henholdsvis enthesitis og dactylitis ved baseline.
English: Q. What if I heard more than 2 clicks during my injection-2 loud clicks and a soft one.
Danish: Hvad nu hvis jeg hører mere end 2 klik under indsprøjtningen - 2 høje klik og et lavt klik.
English: Serious hypersensitivity reactions, including some cases of anaphylaxis, angioedema, urticaria and, rarely, late (10-14 days following injection) serious hypersensitivity reactions including widespread urticaria, dyspnea and high antibody titres have been reported.
Danish: Alvorlige overfølsomhedsreaktioner, herunder tilfælde af anafylaksi, angioødem, urticaria og i sjældne tilfælde sene (10-14 dage efter injektion) alvorlige overfølsomhedsreaktioner inklusive udbredt urticaria, dyspnø og høje antistoftitre, er rapporteret.
English: Q. What if I unlocked the pre-filled pen and pressed the green injection button before I twisted off the base cap?
Danish: Hvad nu hvis jeg låser den fyldte pen op og trykker på den grønne injektionsknap, før jeg drejer hætten af?
English: Overdoses up to 240 mg, subcutaneously, as a single administration in clinical trials, have been reported without any serious adverse events.
Danish: Overdoser på op til 240 mg subkutant som en enkelt administration er blevet rapporteret i kliniske studier uden alvorlige bivirkninger.
English: If such an infection develops, monitor carefully and discontinue Taltz if the patient is not responding to standard therapy or the infection becomes serious.
Danish: Hvis der udvikles en sådan infektion, skal patienten overvåges nøje, og Taltz skal seponeres, hvis patienten ikke responderer på standardbehandling, eller hvis infektionen bliver alvorlig.
English: This medicine works by neutralising the activity of a protein called IL-17A, which promotes psoriasis and psoriatic arthritis.
Danish: Dette lægemiddel virker ved at modvirke aktiviteten af et protein kaldet IL-17A, som fremmer udviklingen af psoriasis og psoriasisartrit.
English: Pharmacotherapeutic group: Immunosuppressants, interleukin inhibitors, ATC code: L04AC13
Danish: Farmakoterapeutisk klassifikation: Immunsuppressiva, interleukinhæmmere, ATC-kode: L04AC13.
English: Ixekizumab belongs to a group of medicines called interleukin (IL) inhibitors.
Danish: Ixekizumab tilhører en gruppe af lægemidler, der kaldes interleukin-hæmmere (IL-hæmmere).
English: In SPIRIT-P1and SPIRIT-P2, improvements were shown in all components of the ACR scores including patient assessment of pain.
Danish: SPIRIT-P1 og SPIRIT-P2, viste en forbedring i alle komponenter af ACR-scoren, herunder patienternes smertevurdering.
English: Ixekizumab is a recombinant humanised monoclonal antibody produced in CHO cells.
Danish: Ixekizumab er et rekombinant humaniseret monoklonalt antistof fremstillet i CHO-celler.
English: Via Gramsci 731/733 50019 Sesto Fiorentino (FI) Italy.
Danish: Via Gramsci 731/733 50019 Sesto Fiorentino (FI) Italien
English: Non-clinical studies have not been conducted to evaluate the carcinogenic or mutagenic potential of ixekizumab.
Danish: Der er ikke udført prækliniske studier til vurdering af ixekizumabs karcinogene eller mutagene potentiale.
English: Q. What if the needle did not retract after my injection?
Danish: Hvad nu hvis nålen ikke trækker sig tilbage efter indsprøjtningen?
English: Do not use this medicine after the expiry date which is stated on the pen label and on the outer carton after “EXP”.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på etiketten på pennen og på den ydre karton efter “EXP”.
English: If you stop using Taltz
Danish: Hvis du holder op med at bruge Taltz
English: An association between immunogenicity and treatment emergent adverse events has not been clearly established.
Danish: En sammenhæng mellem immunogenicitet og behandlingsrelaterede bivirkninger er ikke blevet klart fastslået.
English: Exposure (AUC) increased proportionally over a dose range of 5 to 160 mg given as a subcutaneous injection.
Danish: Eksponeringen (AUC) blev øget proportionalt over et dosisinterval på 5-160 mg givet som subkutan injektion.
English: A significantly greater proportion of patients treated with TALTZ achieved a reduction in the PROs of severity of genital pain, genital itch, impact of genital psoriasis on sexual activity, and Dermatology Quality of Life Index (DLQI).
Danish: En signifikant større andel patienter behandlet med Taltz opnåede en reduktion i de patientrapporterede resultater angående sværhedsgraden af genital smerte, genital kløe, genital psoriasis's påvirkning på den seksuelle aktivitet samt Dermatology Quality of Life Index (DLQI).
English: decision should be made whether to discontinue breast-feeding or to discontinue Taltz taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Danish: Det skal besluttes, om amning skal ophøre eller behandling med Taltz seponeres, idet der tages højde for fordelene ved amning for barnet i forhold til de terapeutiske fordele for moderen.
English: A. It is normal to sometimes have air bubbles in the syringe.
Danish: Det er helt normalt, at der nogle gange er luftbobler i injektionssprøjten.
English: Ixekizumab is a monoclonal antibody and is expected to be degraded into small peptides and amino acids via catabolic pathways in the same manner as endogenous immunoglobulins.
Danish: Ixekizumab er et monoklonalt antistof og forventes at blive nedbrudt til små peptider og aminosyrer via katabolisering på samme måde som endogene immunglobuliner.
English: Based on population pharmacokinetic analysis with a limited number of elderly patients (n = 94 for age ≥ 65 years and n = 12 for age ≥ 75 years), clearance in elderly patients and patients less than 65 years of age was similar.
Danish: Baseret på populationsfarmakokinetiske analyser hos et begrænset antal ældre patienter (94 ≥ 65 år og 12 ≥ 75 år) var clearance af samme størrelsesorden hos ældre patienter og patienter under 65 år.
English: List of adverse reactions in clinical studiesa and postmarketing reports System Organ Class
Danish: Tabel 1 Liste over bivirkninger fra kliniske studiera og postmarketing rapporter Systemorganklasse
English: Tinea infection, Herpes simplex (mucocutaneous)c
Danish: Tinea infektion, Herpes simplex (mukokutan)c
English: In developmental toxicity studies, ixekizumab was shown to cross the placenta and was present in the blood of offspring for up to 6 months of age.
Danish: Studier af udviklingstoksicitet viste, at ixekizumab passerer placenta og er i blodet hos afkommet i op til 6-månedersalderen.
English: Elevated concentrations of IL-17A have been implicated in the pathogenesis of psoriasis by promoting keratinocyte proliferation and activation, as well as in the pathogenesis of psoriatic arthritis.
Danish: Forhøjede koncentrationer af IL-17A har været impliceret i patogenesen af psoriasis ved at fremme proliferation og aktivering af keratinocytter, såvel som i patogenesen af psoriasisartrit.
English: SFQ-item 2 score, “0” (never limited) or
Danish: SFQ-punkt 2 score, “0” (aldrig begrænset)
English: Table 7 Efficacy Results at Week 12 in Adults with Genital Psoriasis in Trial IXORA-Q; NRI a Endpoints
Danish: Tabel 7 Effektresultater ved uge 12 hos voksne med genital psoriasis i studiet IXORA-Q; NRIa
English: Based on psoriatic skin biopsy data from a phase I study, there was a dose-related trend towards decreased epidermal thickness, number of proliferating keratinocytes, T cells, and dendritic cells, as well as reductions in local inflammatory markers from baseline to day 43.
Danish: På baggrund af data fra biopsier af psoriasislæderet hud fra et fase I-studie var der en dosisrelateret tendens i retning mod nedsat epidermal tykkelse, nedsat antal af prolifererende keratinocytter, T-celler og dendritiske celler såvel som reduktion i niveauerne af lokale inflammatoriske markører fra baseline til dag 43.
English: DO NOT rub the injection site, as this may cause bruising.
Danish: Gnid IKKE på injektionsstedet, da dette kan give et blåt mærke.
English: Using Taltz will benefit you by improvements of skin clearance and reducing your symptoms such as scaling, itching and pain.
Danish: Behandling med Taltz vil gavne dig ved at forbedre hudens tilstand og mindske dine symptomer som f.eks. hudafskalning, kløe og smerter.
English: It is preferable to avoid the use of Taltz in pregnancy.
Danish: Det bør undgås at anvende Taltz under graviditet.
English: DO NOT inject into areas where the skin is tender, bruised, red, or hard or where you have scars or stretch marks.
Danish: Indsprøjt IKKE i områder, hvor huden er øm, har blå mærker, er rød eller hård, eller hvor du har ar eller strækmærker.
English: Patients had at least moderate plaque psoriasis (defined as sPGA score of ≥ 3 and being candidates for phototherapy and/or systemic therapy) for at least 6 months.
Danish: Patienterne havde som minimum haft moderat plaque-psoriasis (defineret ved en sPGA-score på ≥ 3 og kandidat til lysbehandling og/eller systemisk behandling) i mindst 6 måneder.
English: The mean (SD) maximum plasma concentration (Cmax) of ixekizumab, after the 160 mg starting dose, was 19.9 (8.15) µg/ml.
Danish: Den gennemsnitlige (SD) maksimale plasmakoncentration (Cmax) af ixekizumab efter startdosen på 160 mg var 19,9 (8,15) µg/ml.
English: Concomitant cDMARDs included MTX, leflunomide and sulfasalazine.
Danish: Samtidig behandling med cDMARDs inkluderede MTX, leflunomid og sulfasalazin.
English: ACR 50 and PASI 100 in patients with ≥3% BSA psoriasis skin involvement at baseline, n (%)
Danish: ACR50 og PASI 100 i patienter med ≥3% BSA psoriasisafficeret hud ved baseline, n (%) Uge 24
English: No data are available on the response to live vaccines; there are insufficient data on response to inactive vaccines (see section 5.1).
Danish: Der foreligger ikke tilstrækkelige data om respons på inaktiverede vacciner (se pkt.
English: Taltz contains sodium
Danish: Taltz indeholder natrium
English: • DO NOT continue to use the syringe.
Danish: • Fortsæt IKKE med at bruge injektionssprøjten.
English: Inspect the pre-filled syringe for damage to the outside.
Danish: Undersøg, om den fyldte injektionssprøjte er beskadiget på ydersiden.
English: Approximately 25 % of patients treated with Taltz achieved a PASI score < 5 by Week 2, more than 55 % achieved the PASI score < 5 by Week 4, and increased to 85 % by Week 12 (compared to 3 %, 14 % and 50 % for etanercept).
Danish: Ca. 25 % af de patienter, der blev behandlet med Taltz, havde opnået en PASI-score < 5 i uge 2, mere end 55 % havde opnået PASIscore < 5 i uge 4, og procentdelen var steget til 85 % i uge 12 (sammenlignet med 3 %, 14 % og 50 % for etanercept).
English: Difference from Placebo (95% CI)
Danish: Forskel fra placebo (95% CI)
English: Non-clinical data from cynomolgus monkeys revealed no special hazards for humans based on repeatdose toxicity studies, safety pharmacology evaluations, and reproductive and developmental toxicity studies.
Danish: Prækliniske data fra cynomolgusaber viste ingen særlig risiko for mennesker vurderet ud fra studier af toksicitet efter gentagne doser, sikkerhedsfarmakologi samt reproduktions- og udviklingstoksicitet.
English: Taltz may be stored unrefrigerated for up to 5 days at a temperature not above 30 ºC.
Danish: Taltz kan opbevares uden for køleskab i op til 5 dage ved temperaturer under 30ºC.
English: You should not be given certain types of vaccines while using Taltz.
Danish: Der er visse typer vacciner, som du ikke bør få, mens du bruger Taltz.
English: A total of 7,339 patients have been treated with Taltz in blinded and open-label clinical studies in plaque psoriasis, psoriatic arthritis, and other autoimmune conditions.
Danish: I alt er 7.339 patienter blevet behandlet med Taltz i blindede og open-label kliniske studier med plaque-psoriasis, psoriasisartrit og andre autoimmune sygdomme.
English: PASI-Response Rates from comparative study ixekizumab versus ustekinumab
Danish: Tabel 6 PASI-responsrater fra komparativt studie med ixekizumab versus ustekinumab
English: There were also improvements demonstrated in fatigue as assessed by Fatigue severity NRS scores (p<0.001).
Danish: Der var ligeledes forbedringer i træthedsscoren, målt ved Fatigue severity NRS- score (p<0,001).
English: • Remove the needle from your skin.
Danish: • Træk nålen ud af huden.
English: Maintained or Achieved PASI 75
Danish: Opretholdt eller opnået PASI 75
English: Neutropeniag, Thrombocytopeniag
Danish: Neutropenig, trombocytopenig
English: Minimal Disease Activity (MDA) n (%) Week 24
Danish: Minimal sygdomsaktivitet (MDA) n (%) Uge 24
English: Pull the needle cap off and throw it away.
Danish: Træk nålehætten af og kasser den.
English: DO NOT use any heat sources to warm the medicine, for example: a microwave, hot water, or direct sunlight.
Danish: Brug IKKE nogen form for varmekilde til at opvarme medicinen, hverken en mikrobølgeovn, varmt vand eller direkte sollys.
English: 1a Take the pre-filled pen from the refrigerator.
Danish: 1a Tag den fyldte pen ud af køleskabet.
English: Following a single subcutaneous dose of ixekizumab in patients with psoriasis, mean peak concentrations were achieved within 4 to 7 days, across a dose range of 5 to 160 mg.
Danish: Efter en enkelt subkutan dosis af ixekizumab hos patienter med psoriasis blev de gennemsnitlige maksimale koncentrationer nået inden for 4-10 dage over et dosisinterval på 5-160 mg.
English: Ixekizumab is an IgG4 monoclonal antibody that binds with high affinity (< 3 pM) and specificity to interleukin 17A (both IL-17A and IL-17A/F).
Danish: Ixekizumab er et monoklonalt antistof af typen IgG4, der med høj affinitet (< 3 pM) og specificitet binder sig til interleukin 17A (både IL-17A og IL-17A/F).
English: A significantly greater proportion of patients treated with Taltz achieved a DLQI 0 or 1.
Danish: En signifikant større andel af patienter behandlet med Taltz opnåede en DLQI-score på 0 eller 1.
English: Injection button Lock ring Lock/unlock symbols
Danish: Injektionsknap Låsering Symboler for 'låst'/'ulåst'
English: N with baseline GPSS Itch NRS Score ≥3 N=62 N=60 GPSS Genital Itch (≥3 point improvement) N with baseline SFQ Item 2 Score ≥2
Danish: N med baseline GPSS Itch NRS Score ≥3 N = 62 N = 60 GPSS Genital Itch (≥3 points forbedring)
English: Tell your doctor, pharmacist or nurse - if you are using, have recently used or might use any other medicine.
Danish: Fortæl lægen, apotekspersonalet eller sundhedspersonalet - hvis du bruger anden medicin eller har gjort det for nylig.
English: If you have forgotten to inject a dose of Taltz, talk to your doctor.
Danish: Hvis du har glemt at tage Taltz Hvis du har glemt at indsprøjte en dosis Taltz, skal du tale med lægen.
English: sPGA of “0” or “1” is equivalent to “clear” or “minimal”; NRS = Numeric Rating Scale
Danish: sPGA på “0” eller “1” er svarende til “clear” eller “minimal”; NRS = Numeric Rating Scale
English: You and your doctor or nurse should decide if you should inject Taltz yourself.
Danish: Du og lægen eller sygeplejersken bør sammen afgøre, om du selv skal foretage Taltz-indsprøjtningerne.
English: UNCOVER-3 enrolled 1,346 patients.
Danish: I UNCOVER-3 blev der inkluderet 1.346 patienter.
English: Caution should be exercised when prescribing Taltz to patients with inflammatory bowel disease, including Crohn's disease and ulcerative colitis, and patients should be monitored closely.
Danish: Taltz skal ordineres med forsigtighed til patienter med inflammatorisk tarmsygdom, herunder Crohns sygdom og colitis ulcerosa, og patienterne skal følges tæt.
English: A weekly subcutaneous dose of 50 mg/kg to monkeys is approximately 19 times the 160 mg starting dose of Taltz and in monkeys results in exposure (AUC) that is at least 61-fold higher than the predicted mean steady-state exposure in humans administered the recommended dose regimen.
Danish: En ugentlig subkutan dosis på 50 mg/kg hos aber er ca. 19 gange startdosen af Taltz på 160 mg og resulterer i en eksponering (AUC) hos aber, som er mindst 61 gange højere end den beregnede gennemsnitlige eksponering ved steady state hos mennesker, der får det anbefalede dosisregime.
English: Among these patients, 71.5 % regained at least an sPGA (0,1) response within 12 weeks of restarting treatment with Taltz 80 mg Q4W.
Danish: Blandt disse patienter genvandt 71,5 % som minimum et sPGA (0,1)-respons inden for 12 uger efter genoptagelse af behandling med Taltz 80 mg Q4W.
English: In a study in healthy subjects, no safety concerns were identified of two inactivated vaccines (tetanus and pneumococcal), received after two doses of ixekizumab (160 mg followed by a second dose of 80 mg two weeks later).
Danish: I et studie med raske forsøgspersoner blev der ikke konstateret nogen sikkerhedsmæssige problemer ved to inaktiverede vacciner (tetanus og pneumokok) givet efter to doser ixekizumab (160 mg efterfulgt af en dosis på 80 mg to uger senere).
English: DO NOT touch the needle.
Danish: Rør IKKE ved nålen.
English: Over the entire treatment period infections were reported in 52.8 % of patients treated with Taltz (46.9 per 100 patient years).
Danish: Over hele behandlingsperioden blev der rapporteret infektioner hos 52,8 % af de patienter, der blev behandlet med Taltz (46,9 pr. 100 patientår).
English: Itch NRS reduction
Danish: Reduktion i Itch NRS på
English: UNCOVER-2 enrolled 1,224 patients.
Danish: I UNCOVER-2 blev der inkluderet 1.224 patienter.
English: The rate of infections was 21.5 % for etanercept and 26.0 % for Taltz, with the majority of the events mild to moderate in severity.
Danish: Forekomsten af infektioner var 21,5 % for etanercept og 26,0 % for Taltz, og størstedelen var lette til moderate i sværhedsgrad.
English: Serious infections were reported in 1.6 % of patients treated with Taltz (1.5 per 100 patient years).
Danish: Alvorlige infektioner blev rapporteret hos 1,6 % af patienterne behandlet med Taltz (1,5 pr. 100 patientår).
English: Do not use this medicine after the expiry date which is stated on the syringe label and on the outer carton after “EXP”.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på etiketten på injektionssprøjten og på den ydre karton efter “EXP”.
English: In plaque psoriasis studies, the safety of Taltz in combination with other immunomodulatory agents or phototherapy has not been evaluated.
Danish: I studier med plaque-psoriasis er sikkerheden af Taltz i kombination med andre immunmodulerende midler eller lysbehandling er ikke blevet evalueret.
English: Significantly greater improvements at Week 12 from baseline compared to placebo and etanercept were demonstrated in nail psoriasis (as measured by the Nail Psoriasis Severity Index [NAPSI]), in scalp psoriasis (as measured by Psoriasis Scalp Severity Index [PSSI]) and in palmoplantar psoriasis (as measured by Psoriasis Palmoplantar Severity Index [PPASI]).
Danish: Der blev påvist signifikant større forbedringer fra baseline til uge 12 sammenlignet med placebo og etanercept ved neglepsoriasis (målt ved Nail Psoriasis Severity Index [NAPSI]), ved psoriasis i hovedbunden (målt ved Psoriasis Scalp Severity Index [PSSI]) og ved palmoplantar psoriasis (målt ved Psoriasis Palmoplantar Severity Index [PPASI]).
English: In all three studies, the co-primary endpoints were the proportion of patients who achieved a PASI 75 response (Psoriasis Area and Severity Index) and an sPGA of 0 (“clear”) or 1 (“minimal”) response at Week 12 versus placebo.
Danish: I alle tre studier var de co-primære endepunkter andelen af patienter, der opnåede en PASI 75-score (Psoriasis Area and Severity Index) og en sPGA-score på 0 (“clear” [ingen symptomer]) eller 1 (“minimal” [minimale symptomer]) ved uge 12 versus placebo.
English: Significant improvements in itch severity were seen at Week 1 in patients treated with Taltz.
Danish: Der blev set signifikante forbedringer i sværhedsgraden af kløe ved uge 1 hos de patienter, der blev behandlet med Taltz.
English: You and your doctor should decide if you will breast-feed or use Taltz.
Danish: Du og lægen skal sammen afgøre, om du skal amme eller bruge Taltz.
English: No effects on reproductive organs, menstrual cycles or sperm were observed in sexually mature cynomolgus monkeys that received ixekizumab for 13 weeks at a weekly subcutaneous dose of 50 mg/kg.
Danish: Der blev ikke observeret virkninger på reproduktionsorganer, menstruationscyklus eller sæd hos seksuelt modne cynomolgusaber, som fik ixekizumab 50 mg/kg subkutant ugentligt i 13 uger.
English: Treatment with Taltz is associated with an increased rate of infections such as upper respiratory tract infection, oral candidiasis, conjunctivitis, and tinea infections (see section 4.8).
Danish: Behandling med Taltz er forbundet med en øget forekomst af infektioner, f.eks. infektion i øvre luftveje, oral candidiasis, konjunktivitis og tinea-infektioner (se pkt.
English: Let the injection site dry naturally before you inject your medicine.
Danish: Lad injektionsstedet tørre af sig selv, før du indsprøjter medicinen.
English: The most frequently reported adverse drug reactions (ADRs) were injection site reactions and upper respiratory tract infections (most frequently nasopharyngitis).
Danish: De hyppigst rapporterede bivirkninger er reaktioner på injektionsstedet og infektioner i øvre luftveje (oftest nasofaryngitis).
English: In the population PK analysis, mean serum clearance was 0.0161 L/hr.
Danish: I populationsfarmakokinetiske analyser var den gennemsnitlige serumclearance 0,0161 l/t.
English: - if you are receiving any other treatment for psoriasis (such as immunosuppressant or phototherapy with ultraviolet light) or for psoriatic arthritis.
Danish: - hvis du får anden behandling mod psoriasis (f.eks. et lægemiddel, der undertrykker dit immunsystem, eller lysbehandling med ultraviolet lys) eller mod psoriasisartrit.
English: Eli Lilly Italia S.p.A.,Via Gramsci 731/733, 50019, Sesto Fiorentino (FI), Italy.
Danish: Fremstiller Eli Lilly Italia S.p.A.,Via Gramsci 731/733, 50019, Sesto Fiorentino (FI), Italien.
English: In addition, the corresponding frequency category for each ADR is based on the following convention: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000
Danish: Hyppighedskategorien for de enkelte bivirkninger er baseret på følgende konvention: meget almindelig (≥ 1/10), almindelig (≥ 1/100 til
English: The second loud click tells you that your injection is complete.
Danish: Det andet høje klik fortæller dig, at indsprøjtningen er gennemført.
English: 0.1% of patients receiving Taltz developed a neutrophil count <1000 cells/mm3.
Danish: 0,1 % af patienterne behandlet med Taltz udviklede et neutrofiltal <1.000 celler/mm3.
English: A. When your injection is complete:
Danish: Når indsprøjtningen er gennemført:
English: Your doctor will decide how much Taltz you need and for how long.
Danish: Hvor meget Taltz skal gives, og hvor længe Lægen vil afgøre, hvor meget Taltz du skal have, og hvor længe du skal have det.
English: You should see the green plunger rod showing through the syringe body when the injection is complete.
Danish: Du skal kunne se den grønne stempelstang gennem sprøjtecylinderen, når injektionen er gennemført.
English: Onset of response was superior on PASI 75 as early as week 2 (p < 0.001) and on PASI 90 and PASI 100 by week 4 (p < 0.001).
Danish: Responsstart var superior på PASI 75 allerede ved uge 2 (p < 0,001), og på PASI 90 og PASI 100 ved uge 4 (p < 0,001).
English: DO NOT put the needle cap back on-you could damage the needle or injure yourself by accident.
Danish: Sæt IKKE nålehætten på igen - du kan komme til ødelægge nålen eller stikke dig selv ved et uheld.
English: Gently pinch and hold a fold of skin where you will inject.
Danish: Knib forsigtigt huden sammen og lav en hudfold der, hvor du vil indsprøjte.
English: If you are not sure if any of the above applies to you, talk to your doctor or nurse before using Taltz.
Danish: Hvis du er i tvivl, om noget af ovenstående gælder for dig, så tal med lægen eller sundhedspersonalet, før du bruger Taltz.