FrancophonIA/ELRC3.0 huggingface dataset:
English: saquinavir, rifabutin, efavirenz - a medicine used to treat depression called nefazodone - medicines used to treat epilepsy called phenytoin, carbamazepine, phenobarbital - a herbal medicine used to treat depression called St. John's wort - a medicine used to treat tuberculosis called rifampicin - a medicine used for strong pain relief called alfentanil - medicines used to prevent organ rejection after an organ transplant called ciclosporin, sirolimus,
Croatian: nelfinavir, ritonavir, sakvinavir, rifabutin, efavirenz - lijek koji se primjenjuje za liječenje depresije, pod nazivom nefazodon - lijekovi koji se primjenjuju za liječenje epilepsije kao što su fenitoin, karbamazepin,
English: VITRAKVI 25 mg hard capsules VITRAKVI 100 mg hard capsules
Croatian: NAZIV LIJEKA VITRAKVI 25 mg tvrde kapsule VITRAKVI 100 mg tvrde kapsule
English: Anaemia
Croatian: Melanoma
English: VITRAKVI 100 mg hard capsules larotrectinib
Croatian: NAZIV LIJEKA VITRAKVI 100 mg tvrde kapsule larotrektinib
English: Investigations
Croatian: Pregled ispitivanja
English: 6.6 Special precautions for disposal and other handling
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom Upute za primjenu:
English: Nausea Vomiting
Croatian: Debelo crijevoa
English: Bayer plc Tel: +44-(0)118 206 3000
Croatian: Tel: +44-(0)118 206 3000
English: VITRAKVI 20 mg/mL oral solution
Croatian: NAZIV LIJEKA VITRAKVI 20 mg/ml oralna otopina
English: - The recommended dose of VITRAKVI is 100 mg (1 capsule of 100 mg or 4 capsules of 25 mg),
Croatian: Odrasli (stariji od 18 godina) - Preporučena doza lijeka VITRAKVI je 100 mg (1 kapsula od 100 mg ili 4 kapsule od 25 mg),
English: a Grade 4 reactions were reported
Croatian: Prijavljene su nuspojave 4. stupnja
English: VITRAKVI as monotherapy is indicated for the treatment of adult and paediatric patients with solid tumours that display a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion, - who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity, and - who have no satisfactory treatment options (see sections 4.4 and 5.1).
Croatian: - koji imaju lokalno uznapredovalu ili metastaziranu bolest ili u kojih bi kirurška resekcija vjerojatno mogla rezultirati teškim morbiditetom te - za koje nema zadovoljavajućih mogućnosti liječenja (vidjeti dijelove 4.4 i 5.1).
English: Alanine aminotransferase (ALT) increased Aspartate aminotransferase (AST) increased Weight increased (Abnormal weight gain)
Croatian: povišena alanin aminotransferaza (ALT) povišena aspartat aminotransferaza (AST) povećanje tjelesne težine (abnormalni dobitak na tjelesnoj težini)
English: VITRAKVI 25 mg hard capsules larotrectinib
Croatian: NAZIV LIJEKA VITRAKVI 25 mg tvrde kapsule larotrektinib
English: Resume at the next dose modification if resolution occurs within 4 weeks.
Croatian: Ako se nuspojava povuče u roku od 4 tjedna, nastavite primjenu lijeka sa sljedećom prilagođenom dozom.
English: Bayer S.p.A. Tel: +39 02 397 8 1
Croatian: Tel: +39 02 397 8 1
English: Biliary (n=2) SCLC (n=1)b, d Appendix (n=1) Breast (n=1)
Croatian: b,c primarni SŽS-a (n=4) GIST (n=2)a žučni (n=2) SCLC (n=1)b,d crvuljak (n=1) dojka (n=1) sarkom kosti (n=1) gušterača (n=1)
English: 50 mg/m2 twice daily
Croatian: 50 mg/m2 dvaput na dan
English: Myalgia
Croatian: dimetikon
English: Anaemia Neutrophil count decreased (Neutropenia) Leukocyte count decreased (Leukopenia)
Croatian: anemija smanjen broj neutrofila (neutropenija) smanjen broj leukocita (leukopenija)
English: VITRAKVI 100 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU VITRAKVI 100 mg
English: 25 mg/m2 twice daily
Croatian: 25 mg/m2 dvaput na dan
English: Myalgia Muscular weakness
Croatian: Infantilni fibrosarkoma Štitna žlijezdaa
English: Tube diameter for high density feeds
Croatian: Promjer sonde za pripravke visoke gustoće
English: Neutrophil count decreased (Neutropenia)a Leukocyte count decreased (Leukopenia)
Croatian: smanjen broj neutrofila (neutropenija) smanjen broj leukocita (leukopenija)
English: EU/1/19/1385/001
Croatian: 12. BROJ ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/19/1385/001
English: VITRAKVI 25 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU VITRAKVI 25 mg
English: Effect of gastric pH-elevating agents on larotrectinib Larotrectinib has pH-dependent solubility.
Croatian: Učinak lijekova koji povisuju želučani pH na larotrektinib
English: 75 mg/m2 twice daily
Croatian: 75 mg/m2 dvaput na dan
English: Pancreasa
Croatian: Gušteračaa
English: EU/1/19/1385/003
Croatian: 12. BROJ ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/19/1385/003
English: Do not breast-feed while taking this medicine and for 3 days after the last dose.
Croatian: Nemojte dojiti za vrijeme uzimanja ovog lijeka i tijekom 3 dana nakon zadnje doze zato što nije poznato prelazi li VITRAKVI u majčino mlijeko.
English: EU/1/19/1385/002
Croatian: 12. BROJ ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/19/1385/002
English: Primary CNSb
Croatian: Primarni tumor SŽS-a b
English: Each mL of oral solution contains larotrectinib sulfate, equivalent to 20 mg of larotrectinib.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedan ml oralne otopine sadrži larotrektinibsulfat, što odgovara 20 mg larotrektiniba.
English: Very common Myalgia Muscular weakness
Croatian: Poremećaji mišićnokoštanog sustava i vezivnog tkiva vrlo često mialgija mišićna slabost često mialgija
English: Patients with and without documented NTRK gene fusion were allowed to participate in Study 1 and Study 3 (“SCOUT”).
Croatian: U ispitivanju 1 i ispitivanju 3 („SCOUT“) smjeli su sudjelovati bolesnici s dokumentiranim fuzijskim genom NTRK i bez njega.
English: Bayer spol.
Croatian: Bayer OÜ
English: Dysgeusia
Croatian: Neurotrophic
English: Propylene glycol (E 1520) Potassium sorbate (E 202) Methyl parahydroxybenzoate (E 218) Citrus fruit flavour
Croatian: 6.1 Popis pomoćnih tvari pročišćena voda saharoza hidroksipropilbetadeks glicerol (E 422) sorbitol (E 420) natrijev citrat (E 331) natrijev dihidrogenfosfat dihidrat (E 339) citratna kiselina (E 330) propilenglikol (E 1520) kalijev sorbat (E 202) metilparahidroksibenzoat (E 218) aroma citrusa prirodni okus
English: Capsule shell: - Gelatin - Titanium dioxide (E 171) Printing ink: - Shellac - Indigo carmine aluminium lake (E 132) - Titanium dioxide (E 171) - Propylene glycol (E 1520) - Dimeticone
Croatian: Ovojnica kapsule: - želatina - titanijev dioksid (E 171) Boja za otisak:
English: Marketing Authorisation Holder
Croatian: • Uvjetno odobrenje za stavljanje lijeka u promet
English: One reported Grade 3 case each of Neutrophil count decreased (Neutropenia), Paraesthesia, Myalgia, Weight increased (Abnormal weight gain).
Croatian: (neutropenija), parestezija, mijalgija, povećanje tjelesne težine (abnormalni dobitak na tjelesnoj težini).
English: Alanine aminotransferase (ALT) increased Aspartate aminotransferase (AST) increased Weight increased (Abnormal weight gain) Blood alkaline phosphatase increased
Croatian: povišena alkalna fosfataza u krvi povišena alanin aminotransferaza (ALT) povišena aspartat aminotransferaza (AST) povećanje tjelesne težine (abnormalni dobitak na tjelesnoj težini)
English: below.
Croatian: Tel.
English: Very common Anaemia Neutrophil count decreased (Neutropenia) Leukocyte count decreased (Leukopenia)
Croatian: često anemija smanjen broj neutrofila (neutropenija)a smanjen broj leukocita (leukopenija)
English: Analysis in solid tumours excluding primary CNS tumours (n=93)a
Croatian: Analiza u solidnih tumora izostavljajući primarne tumore SŽS-a
English: Neonate
Croatian: Novorođenčad
English: Each mL of oral solution contains larotrectinib sulfate equivalent to 20 mg of larotrectinib.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedan ml oralne otopine sadrži 20 mg larotrektiniba u obliku larotrektinibsulfata.
English: Alanine aminotransferase (ALT) increased Aspartate aminotransferase (AST) increased Blood alkaline phosphatase increased
Croatian: povišena alkalna fosfataza u krvi povišena alanin aminotransferaza (ALT)
English: - A suitable syringe should be used to administer VITRAKVI to the nasogastric feeding tube.
Croatian: - Za primjenu lijeka VITRAKVI kroz nazogastričnu sondu potrebno je koristiti odgovarajuću štrcaljku.
English: PD
Croatian: NTRK
English: VITRAKVI 100 mg hard capsules Each hard capsule contains larotrectinib sulfate equivalent to 100 mg of larotrectinib.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna kapsula sadrži 100 mg larotrektiniba u obliku larotrektinibsulfata.
English: Study 1
Croatian: PRILOG I.
English: - VITRAKVI should not be mixed with feeding formulas, if administered via nasogastric feeding tube.
Croatian: Izračunat volumen doze treba zaokružiti na najbližih 0,2 ml - VITRAKVI se ne smije miješati s enteralnim formulama ako se primjenjuje putem nazogastrične sonde.
English: - The recommended dose of VITRAKVI is 100 mg (5 mL), two times a day.
Croatian: Odrasli (stariji od 18 godina) - Preporučena doza lijeka VITRAKVI je 100 mg (5 ml), dvaput na dan.
English: - VITRAKVI should be permanently discontinued if an adverse reaction does not resolve within
Croatian: - Ako se nuspojava ne povuče u roku od 4 tjedna, primjenu lijeka VITRAKVI potrebno je trajno prekinuti.
English: VITRAKVI 25 mg hard capsules Each hard capsule contains larotrectinib sulfate equivalent to 25 mg of larotrectinib.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna kapsula sadrži 25 mg larotrektiniba u obliku larotrektinibsulfata.
English: Bone sarcoma (n=1) Pancreas (n=1)
Croatian: b,d crvuljak (n=1) dojka (n=1) sarkom kosti (n=1) gušterača (n=1)
English: Talk to your doctor, pharmacist or nurse or go to a hospital straight away.
Croatian: Ako uzmete više lijeka VITRAKVI nego što ste trebali Odmah se obratite liječniku, ljekarniku ili medicinskoj sestri ili otiđite u bolnicu.
English: - Turn the bottle the right way up and remove the oral syringe from the bottle adapter.
Croatian: - Povucite klip prema dolje do graduacijske oznake koja pokazuje propisanu količinu u ml. - Okrenite bocu dnom prema dolje i izvadite štrcaljku za usta iz adaptera boce.
English: Atriance (nelarabine)
Croatian: Atriance (nelarabin)
English: Most of these side effects were also very common in children.
Croatian: Većina ovih nuspojava vrlo se često javljala i u djece.
English: This schedule can also be used in patients aged 16 to 21 years.
Croatian: Taj se raspored može primijeniti i na bolesnike u dobi od 16 do 21 godine.
English: Further information on Atriance can be found on the Agency's website: https://www.ema.europa.eu/en/medicines/human/EPAR/atriance
Croatian: Više informacija o lijeku Atriance dostupno je na internetskim stranicama Agencije: https://www.ema.europa.eu/en/medicines/human/EPAR/atriance
English: The first study involved 70 children and young adults below 21 years of age.
Croatian: U prvom je ispitivanju sudjelovalo 70 djece i mladih odraslih osoba mlađih od 21 godinu.
English: Atriance has been authorised under ‘exceptional circumstances'.
Croatian: Lijek Atriance odobren je u „iznimnim okolnostima”.
English: This means that because the diseases are rare, it has not been possible to obtain complete information about Atriance.
Croatian: To znači da, budući da je riječ o rijetkim bolestima, nije moguće dobiti potpune informacije o lijeku Atriance.
English: It belongs to the group of cancer medicines called ‘antimetabolites'.
Croatian: Pripada skupini lijekova protiv raka koji se nazivaju „antimetaboliti”.
English: Atriance received a marketing authorisation valid throughout the EU on 22 August 2007.
Croatian: Lijek Atriance dobio je odobrenje za stavljanje u promet koje je na snazi u EU-u od 22. kolovoza 2007.
English: The dose and frequency of infusion depend on the patient's age and body surface area (calculated using the patient's height and weight).
Croatian: Doza i učestalost infuzije ovise o dobi i tjelesnoj površini bolesnika (izračunava se prema visini i tjelesnoj težini bolesnika).
English: The most common side effects with Atriance in adults (which may affect more than 1 in 10 people) are infection, febrile neutropenia (low white blood cell counts with fever), neutropenia (low white blood cell counts), thrombocytopenia (low platelet counts), anaemia (low red blood cell counts), somnolence (sleepiness), peripheral neuropathy (damage to the nerves in the extremities), hypoaesthesia (a reduced sense of touch), paraesthesia (unusual sensations like pins and needles), dizziness, headache, dyspnoea (breathlessness), cough, diarrhoea, vomiting, constipation, nausea (feeling sick), myalgia (muscle pain), oedema (swelling), peripheral oedema (swelling in ankles and feet), pyrexia (fever), pain, tiredness and weakness.
Croatian: Najčešće nuspojave lijeka Atriance u odraslih osoba (koje se mogu javiti u više od 1 na 10 osoba) jesu infekcija, febrilna neutropenija (niska razina bijelih krvnih stanica praćena vrućicom), neutropenija (niska razina bijelih krvnih stanica), trombocitopenija (niska razina trombocita), anemija (niska razina crvenih krvnih stanica), somnolencija (pospanost), periferna neuropatija (oštećenje živaca u udovima), hipoestezija (smanjen osjećaj dodira), parestezija (neobični osjećaji poput trnaca i probadanja), omaglica, glavobolja, dispneja (otežano disanje), kašalj, proljev, povraćanje, konstipacija, mučnina (slabost), mijalgija (bol u mišićima), edem (oticanje), periferni edem (oticanje u gležnjevima i stopalima), pireksija (vrućica), bol, umor i slabost.
English: Treatment should be stopped if the patient develops serious side effects affecting the brain or nervous system.
Croatian: Liječenje treba prekinuti ako u bolesnika nastupe ozbiljne nuspojave koje utječu na mozak ili živčani sustav.
English: This stops the production of DNA and thus slows down the growth and multiplication of cells.
Croatian: To zaustavlja proizvodnju DNK-a i time se usporavaju rast i dioba stanica.
English: These are types of cancer where T-lymphoblasts (a type of immature white blood cell) multiply too quickly.
Croatian: To su vrste raka u kojima se T-limfoblasti (vrsta nezrelih bijelih krvnih stanica) prebrzo množe.
English: What measures are being taken to ensure the safe and effective use of Atriance?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Atriance?
English: Of those whose cancer had not responded (28) five (18%) had a complete response to treatment.
Croatian: Od onih bolesnika kod kojih rak nije reagirao (28), kod petero (18 %) bolesnika zabilježen je potpuni odgovor na terapiju.
English: In the second study, involving a total of 40 adults and adolescents above the age of 16.
Croatian: Drugo je ispitivanje obuhvaćalo ukupno 40 odraslih osoba i adolescenata starijih od 16 godina.
English: Agency will review any new information that may become available and this overview will be updated as necessary.
Croatian: Agencija svake godine procjenjuje sve nove informacije koje postanu dostupne te se ovaj sažetak po potrebi ažurira.
English: What is Atriance and what is it used for?
Croatian: Što je Atriance i za što se koristi?
English: Atriance was shown to be effective in two main studies involving patients with T-ALL and T-LBL whose cancer had stopped responding to one or more previous cancer treatments.
Croatian: Atriance se pokazao djelotvornim u dvama glavnim ispitivanjima u kojima su sudjelovali bolesnici oboljeli od T-ALL-a i T-LBL-a čiji je rak prestao reagirati na jedno ili više prethodnih liječenja.
English: Other information about Atriance
Croatian: Ostale informacije o lijeku Atriance
English: Side effects reported with Atriance are carefully evaluated and any necessary action taken to protect patients.
Croatian: Nuspojave prijavljene za lijek Atriance pažljivo se procjenjuju i poduzimaju se potrebne mjere za zaštitu bolesnika.
English: Severe side effects affecting the brain and nervous system have also been reported in patients taking Atriance, including somnolence, convulsions, and peripheral neuropathy causing numbness, unusual sensations, weakness and even paralysis.
Croatian: Teške nuspojave koje utječu na mozak i živčani sustav zabilježene su i u bolesnika koji su uzimali lijek Atriance, uključujući somnolenciju, konvulzije i perifernu neuropatiju, koja dovodi do osjećaja obamrlosti, neobičnih osjećaja, slabosti, pa čak i paralize.
English: The European Medicines Agency decided that Atriance's benefits are greater than its risks and it can be authorised for use in the EU.
Croatian: Europska agencija za lijekove zaključila je da koristi od lijeka Atriance nadmašuju s njim povezane rizike te da lijek može biti odobren za primjenu u EU-u.
English: Since Atriance has been authorised under exceptional circumstances, the company that markets Atriance will provide yearly updates from a study on the effectiveness and safety of Atriance in children and young adults.
Croatian: Budući da je lijek Atriance odobren u iznimnim okolnostima, tvrtka koja stavlja lijek Atriance u promet dostavit će godišnja ažuriranja o sigurnosti i djelotvornosti lijeka Atriance u djece i mladih odraslih osoba.
English: Patients receiving Atriance should be monitored regularly for changes in blood cell counts and should receive adequate hydration if they are at risk of tumour lysis syndrome (a complication due to the breakdown of cancer cells).
Croatian: Bolesnike koji primaju lijek Atriance treba redovito nadzirati radi mogućih promjena u broju krvnih stanica te bi trebali dobiti odgovarajuću hidrataciju ako su izloženi riziku od sindroma lize tumora (komplikacije koja nastaje zbog razgradnje stanica raka).
English: An overview of Atriance and why it is authorised in the EU
Croatian: Pregled informacija o lijeku Atriance i zašto je odobren u EU-u
English: Patients aged under 16 years receive a dose of 650 mg per square metre given over one hour on five consecutive days, repeated every 21 days.
Croatian: Bolesnici mlađi od 16 godina primaju dozu od 650 mg po četvornom metru tjelesne površine, a lijek se daje pet uzastopnih dana po sat vremena, što se ponavlja svakih 21 dan.
English: The Agency noted that, due to the small number of patients with these diseases, the information to support the authorisation of Atriance is limited, but it agreed that the medicine could allow some patients to go on to receive bone-marrow transplantation, increasing their chances of survival.
Croatian: Agencija je napomenula da su informacije koje govore u prilog odobrenju lijeka Atriance ograničene zbog malenog broja bolesnika oboljelih od tih bolesti, ali se složila s time da bi lijek nekim bolesnicima mogao omogućiti transplantaciju koštane srži, čime bi se pospješili izgledi za njihovo preživljenje.
English: Of those whose cancer had not responded to two or more previous treatments (39) five (13%) had a complete response to treatment after a month, with no evidence of disease and normal blood counts.
Croatian: Od onih bolesnika kod kojih rak nije reagirao na dvije ili više prethodnih terapija (39), kod petero (13 %) bolesnika zabilježen je potpuni odgovor na terapiju nakon mjesec dana, bez prisutnosti znakova bolesti i uz povratak na uobičajenu razinu broja krvnih stanica.
English: Nelarabine is converted within cells into an analogue of guanine, one of the fundamental chemicals that make up DNA.
Croatian: Nelarabin se u stanicama pretvara u analoga gvanina, jedne od temeljnih sastavnih kemikalija DNK-a.
English: As for all medicines, data on the use of Atriance are continuously monitored.
Croatian: Kao i za sve lijekove, podatci o primjeni lijeka Atriance kontinuirano se prate.
English: What are the risks associated with Atriance?
Croatian: Koji su rizici povezani s lijekom Atriance?
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Atriance have been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Atriance nalaze se u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: For more information about using Atriance, see the package leaflet or contact your doctor or pharmacist.
Croatian: Za više informacija o primjeni lijeka Atriance pročitajte uputu o lijeku, odnosno obratite se liječniku ili ljekarniku.
English: In both studies, the patients were treated with Atriance, but its effects were not compared with those of any other medicine.
Croatian: U obama su ispitivanjima bolesnici liječeni lijekom Atriance, ali njegovi učinci nisu uspoređeni s onima drugih lijekova.
English: In both studies, compared to patients who had a complete response more patients had a partial response to Atriance treatment, with blood counts returning towards normal levels.
Croatian: U obama ispitivanjima, u usporedbi s bolesnicima kod kojih je zabilježen potpuni odgovor, više je bolesnika imalo djelomičan odgovor na terapiju lijekom Atriance i njihov se broj krvnih stanica vratio na uobičajenu razinu.
English: Why is Atriance authorised in the EU?
Croatian: Zašto je lijek Atriance odobren u EU-u?
English: In the body, this analogue takes the place of guanine and interferes with the enzymes involved in making new DNA, DNA polymerases.
Croatian: Taj analog u tijelu preuzima ulogu gvanina i ometa enzime uključene u stvaranje novog DNK-a, odnosno DNK-polimeraze.
English: Atriance is a cancer medicine used to treat patients with T-cell acute lymphoblastic leukaemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LBL).
Croatian: Atriance je lijek protiv raka za liječenje bolesnika oboljelih od akutne limfoblastične leukemije T-stanica (T-ALL) ili limfoblastičnog limfoma T-stanica (T-LBL).
English: Because the guanine analogue accumulates in Tcells and lasts longer in these cells, Atriance slows down the growth and multiplication of the cells involved in T-ALL and T-LBL.
Croatian: Budući da se analog gvanina nakuplja u T-stanicama i u njima traje dulje, lijek Atriance usporava rast i diobu stanica prisutnih kod T-ALL-a i T-LBL-a.
English: The active substance in Atriance, nelarabine, is a cytotoxic, a medicine that kills cells that are dividing, such as cancer cells.
Croatian: Djelatna tvar lijeka Atriance, nelarabin, je citotoksik (lijek koji uništava stanice koje se dijele, kao što su stanice raka).
English: Atriance is used when the cancer has not responded to, or has stopped responding to, at least two types of chemotherapy.
Croatian: Lijek Atriance primjenjuje se kada u bolesnika oboljelih od raka nema odgovora na najmanje dvije vrste kemoterapije ili je taj odgovor prestao.
English: Atriance can only be obtained with a prescription and is given by drip into a vein under the supervision of a doctor who has experience in the use of thes type of medicine.
Croatian: Lijek Atriance izdaje se samo na recept i daje se intravenskim putem (ukapavanjem) pod nadzorom liječnika iskusnog u primjeni ovakve vrste lijeka.
English: How does Atriance work?
Croatian: Kako djeluje Atriance?
English: Patients should be monitored closely for these side effects and treatment stopped if necessary.
Croatian: Bolesnici trebaju biti pod pomnim nadzorom radi moguće pojave ovih nuspojava i terapiju treba prekinuti prema potrebi.
English: Atriance contains the active substance nelarabine.
Croatian: Atriance sadrži djelatnu tvar nelarabin.
English: What information is still awaited for Atriance?
Croatian: Koje se još informacije očekuju o lijeku Atriance?
English: What benefits of Atriance have been shown in studies?
Croatian: Koje su koristi od lijeka Atriance utvrđene u ispitivanjima?
English: In T-ALL the abnormal cells are mainly in the blood and bone marrow, and in T-LBL they are mainly in the lymphatic system (lymph nodes or thymus gland).
Croatian: Kod T-ALL-a abnormalne se stanice većinom nalaze u krvi i koštanoj srži, dok se kod T-LBL-a one većinom nalaze u limfnom sustavu (limfnim čvorovima ili timusu).
English: For the full list of side effects and restrictions of Atriance, see the package leaflet.
Croatian: Potpuni popis nuspojava i ograničenja povezanih s primjenom lijeka Atriance potražite u uputi o lijeku.
English: Treatment may be delayed if other side effects occur.
Croatian: Ako se pojave druge nuspojave, liječenje se može odgoditi.