FrancophonIA/ELRC3.0 huggingface dataset:
English: Concomitant use of PDE-5 inhibitors with INTELENCE may require dose adjustment of the PDE-5 inhibitor to attain the desired clinical effect.
Slovenian: Pri sočasni uporabi zaviralcev PDE-5 z zdravilom INTELENCE je lahko potrebna prilagoditev odmerka zaviralca PDE-5 za doseganje želenega kliničnega učinka.
English: • 1 or more NNRTI resistance-associated mutations (RAMs) at screening or from prior genotypic analysis (i.e., archived resistance)
Slovenian: • 1 ali več mutacij, povezanih z odpornostjo na NNRTI (RAM) pri presejalnem testiranju ali od predhodne analize genotipov (t.j.
English: As a general rule, when deciding to use antiretroviral agents for the treatment of HIV infection in pregnant women, and consequently for reducing the risk of HIV vertical transmission to the newborn, the animal data as well as the clinical experience in pregnant women should be taken into account in order to characterise the safety for the foetus.
Slovenian: V splošnem je pri odločanju uporabe protiretrovirusnega zdravila za zdravljenje infekcije z virusom HIV pri nosečnicah in posledično zmanjšanje tveganja vertikalnega prenosa virusa HIV na novorojenčka potrebno upoštevati tako podatke pri živalih kot tudi klinične izkušnje pri nosečnicah, da se oceni varnost za fetus.
English: Patients who are unable to swallow the tablet(s) whole may disperse the tablet(s) in a glass of water.
Slovenian: Bolniki, ki ne morejo pogoltniti cele tablete (celih tablet), jo (jih) lahko dispergirajo v kozarcu vode.
English: In addition, etravirine demonstrates a fold change (FC) in EC50 ≤ 3 against 60% of 6,171 NNRTI-resistant clinical isolates.
Slovenian: Poleg tega je etravirin pokazal spremembo stopnje (FC - fold change) v vrednosti EC50 ≤ 3 proti 60% od 6.171 kliničnih izolatov, odpornih za NNRTI.
English: Exposure to etravirine was lower (35-50%) in HIV-1 infected patients than in healthy subjects.
Slovenian: Stopnja izpostavljenosti etravirinu je bila pri bolnikih, okuženih s HIV-1 manjša (35-50%), kot pri zdravih preiskovancih.
English: Alternatives to diazepam should be considered.
Slovenian: Premisliti je treba o uporabi nadomestnih zdravil za diazepam.
English: Treatment differences are based on Least Square Means from an ANCOVA model including the stratification factors.
Slovenian: Razlika po zdravljenju se izračuna iz srednjih vrednosti najmanjših kvadratov iz modela ANCOVA, vključno s stratifikacijskimi faktorji.
English: Cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to combination antiretroviral therapy.
Slovenian: Poročali so o primerih osteonekroze, še posebej pri bolnikih s splošno priznanimi dejavniki tveganja, napredovalo okužbo s HIV in/ali dolgotrajno izpostavljenostjo kombinirani protiretrovirusni terapiji.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with INTELENCE in one or more subsets of the paediatric population in human immunodeficiency virus infection, as per Paediatric Investigation Plan (PIP) decision in the granted indication (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila obvezo za predložitev rezultatov študij z zdravilom INTELENCE za eno ali več podskupin pediatrične populacije okužene z virusom humane imunske pomanjkljivosti pod pogoji, ki so za odobreno indikacijo zdravila navedeni v izvedbenem načrtu za pediatrično populacijo (PIP) (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Treatment with INTELENCE should be discontinued if a severe cutaneous reaction develops.
Slovenian: Zdravljenje z zdravilom INTELENCE je treba ukiniti, če se pojavi huda kožna reakcija.
English: If you belong to this age group, please discuss the use of INTELENCE with your doctor.
Slovenian: Če sodite v to starostno skupino, se morate o uporabi zdravila INTELENCE posvetovati s svojim zdravnikom.
English: Since there was a significant interaction effect between treatment and ENF, the primary analysis was done for 2 ENF strata (patients reusing or not using ENF versus patients using ENF de novo).
Slovenian: Ker so ugotovili precejšen medsebojen vpliv z ENF, je bila primarna analiza opravljena na 2 skupinah ENF bolnikov (pri bolnikih, ki so ponovno jemali ENF oziroma ga niso jemali, v primerjavi z bolniki, ki so jemali ENF de novo).
English: HIV infected mothers must not breast-feed, as there is a possibility of infecting the baby with HIV.
Slovenian: Matere, ki so okužene z virusom HIV, ne smejo dojiti, ker obstaja možnost, da bodo z virusom HIV okužile svojega otroka.
English: Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Slovenian: Bolniki z redko dedno galaktozno intoleranco, laponsko obliko zmanjšane aktivnosti laktaze ali malabsorpcijo glukoze in galaktoze ne smejo jemati tega zdravila.
English: The proportion of paediatric patients with < 400 HIV-1 RNA copies/ml was 63.4%.
Slovenian: Delež pediatričnih bolnikov z < 400 HIV-1 RNK kopij/ml je bil 63,4%.
English: Time to onset is usually around 3-6 weeks and the outcome in most cases is favourable upon discontinuation and after initiation of corticosteroid therapy.
Slovenian: Sindrom se običajno pojavi v obdobju 3-6 tednov in v večini primerov izgine po prekinitvi zdravljenja in uvedbi terapije s kortikosteroidi.
English: No unchanged drug was detected in urine so the impact of renal impairment on etravirine elimination is expected to be minimal.
Slovenian: V seču nespremenjenega zdravila niso odkrili, zato je pričakovati, da bo vpliv okvare ledvic na izločanje etravirina minimalen.
English: The frequency rate of the side effects associated with INTELENCE is given below.
Slovenian: Stopnja pogostnosti neželenih učinkov, povezanih z zdravilom INTELENCE je navedena spodaj.
English: As a general rule, it is recommended that mothers infected by HIV do not breastfeed their babies under any circumstances in order to avoid transmission of HIV.
Slovenian: Priporočljivo je, da matere, okužene s HIV, v nobenem primeru ne dojijo svojih otrok, da ne bi prišlo do prenosa virusa HIV na otroka.
English: In clinical trials, Stevens-Johnson Syndrome and erythema multiforme have been rarely (< 0.1%) reported.
Slovenian: V kliničnih študijah so redko poročali o Stevens-Johnsonovem sindromu in o multiformnem eritemu (pri < 0,1% primerov).
English: What INTELENCE is and what it is used for What you need to know before you take INTELENCE How to take INTELENCE
Slovenian: Kaj je zdravilo INTELENCE in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo INTELENCE Kako jemati zdravilo INTELENCE Možni neželeni učinki
English: This difference between treatment arms was statistically significant.
Slovenian: Dobljena razlika med obema skupinama je bila statistično značilna.
English: Pharmacotherapeutic group: Antivirals for systemic use, non-nucleoside reverse transcriptase inhibitors, ATC code: J05AG04.
Slovenian: Farmakoterapevtska skupina: Zdravila za sistemsko zdravljenje virusnih infekcij (nenukleozidni zaviralec reverzne transkriptaze), oznaka ATC: J05AG04.
English: NARCOTIC ANALGESICS Methadone individual dose ranging from 60 mg to 130 mg once daily
Slovenian: NARKOTIČNI ANALGETIKI metadon odmerek v razponu od 60 mg do 130 mg enkrat na dan
English: Some patients taking combination antiretroviral therapy may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Slovenian: Pri nekaterih bolnikih, ki imajo kombinirano protiretrovirusno zdravljenje, lahko pride do bolezni kosti, ki se imenuje osteonekroza (odmiranje kostnega tkiva, ki je posledica zmanjšanja prekrvavitve kosti).
English: The clinical data do not raise safety concern but are very limited.
Slovenian: Klinični podatki so zelo omejeni in ne predstavljajo tveganja glede varnosti.
English: These trials were identical in design and similar efficacy for etravirine was seen in each trial.
Slovenian: Ti dve preskušanji sta bili popolnoma enako načrtovani in v obeh so ugotovili podobno učinkovitost etravirina.
English: Confidence interval around observed difference of response rates; P-value from CMH test controlling for stratification factors = 0.0199 for de novo, and < 0.0001 for not de novo.
Slovenian: Interval zaupanja okrog opaženih razlik v stopnjah odziva; p-vrednost iz CMH testa za nadzor stratifikacijskih faktorjev = 0,0199 za de novo, in < 0,0001 za ne de novo.
English: Delay in stopping INTELENCE treatment after the onset of severe rash may result in a life-threatening reaction.
Slovenian: Odložena prekinitev zdravljenja z zdravilom INTELENCE po pojavu hudega izpuščaja lahko povzroči življensko nevarne reakcije.
English: The clinical significance of the reductions in etravirine pharmacokinetic parameters and boceprevir Cmin in the setting of the combination therapy with HIV antiretroviral medicines which also affect the pharmacokinetics of etravirine and/or boceprevir has not been directly assessed.
Slovenian: Klinični pomen zmanjšanja farmakokinetičnih parametrov etravirina in Cmin boceprevirja pri kombiniranem zdravljenju s HIV protiretrovirusnimi zdravili, ki vplivajo tudi na farmakokinetiko etravirina in/ali boceprevirja ni bil neposredno ovrednoten.
English: However, unbound concentrations have not been assessed.
Slovenian: Vendar pa koncentracij nevezane učinkovine niso ocenjevali.
English: Severe cutaneous and hypersensitivity reactions
Slovenian: Hude kožne in preobčutljivostne reakcije
English: - Stratification: Randomisation was stratified by the intended use of ENF in the BR, previous use of darunavir and screening viral load.
Slovenian: - Stratifikacija: randomizacija je bila stratificirana po namenih uporabe ENF v BR, po predhodni uporabi darunavirja in po virusnem bremenu ob presejalnem testiranju.
English: ANTIBIOTICS Azithromycin
Slovenian: ANTIBIOTIKI azitromicin
English: Confidence interval around observed difference of response rates; P-value < 0.0001 from logistic regression model, including stratification factors.
Slovenian: Interval zaupanja z obeh strani opažene razlike v stopnjah odziva; vrednost p < 0,0001 za model logistične regresije, vključno s stratifikacijskimi faktorji.
English: HMG CO-A REDUCTASE INHIBITORS Atorvastatin
Slovenian: ZAVIRALCI HMG CO-A REDUKTAZE atorvastatin
English: The safety and efficacy of etravirine in children less than 6 years of age and weighing less than 16 kg have not yet been established (see section 5.2).
Slovenian: Varnost in učinkovitost etravirina pri otrocih, starih manj kot 6 let in s telesno maso manjšo od 16 kg, še nista ugotovljeni (glejte poglavje 5.2).
English: When prescribing INTELENCE to females, prescribers should be aware that the incidence of rash was higher in females (see section 4.8).
Slovenian: Pri predpisovanju zdravila INTELENCE ženskam se je treba zavedati, da je bila incidenca izpuščaja pri ženskah večja (glejte poglavje 4.8).
English: This breakpoint might be lower in antiretroviral combination therapy not including a boosted protease inhibitor.
Slovenian: Navedene mejne vrednosti so v kombiniranem protiretrovirusnem zdravljenju, ki ne vključuje okrepljenega zaviralca proteaz, lahko nižje.
English: The most common adverse reaction leading to discontinuation was rash.
Slovenian: Najpogostejši neželeni učinek, ki je vodil do ukinitve zdravila, je bil izpuščaj.
English: The recommended dose for maraviroc when combined with INTELENCE and a PI is 150 mg twice daily, except for fosamprenavir/ritonavir which is not recommended with maraviroc.
Slovenian: Priporočeni odmerek maraviroka pri kombinaciji z zdravilom INTELENCE in zaviralcem proteaze je 150 mg dvakrat na dan, razen pri uporabi s kombinacijo fosamprenavir/ritonavir, ki ni priporočena sočasno z uporabo maraviroka.
English: Although etravirine demonstrates in vitro activity against wild type HIV-2 with median EC50 values ranging from 5.7 to 7.2 µM, treatment of HIV-2 infection with etravirine is not recommended in the absence of clinical data.
Slovenian: Čeprav je in vitro etravirin pokazal delovanje tudi proti divjemu tipu HIV-2 z mediano vrednostjo EC50 v razponu od 5,7 do 7,2 µM (µmol/l), zdravljenje okužbe s HIV-2 z etravirinom ni priporočljivo, ker ni kliničnih podatkov.
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Slovenian: Znaki osteonekroze so okorelost in bolečine sklepov (še posebno kolka, kolena ali rame) in težave pri gibanju.
English: Based on these trial results, etravirine is not recommended for use in combination with N(t)RTIs only in patients who have experienced virological failure on an NNRTI- and N(t)RTI-containing regimen.
Slovenian: Na podlagi izsledkov teh preskušanj lahko ugotovimo, da etravirin ni priporočljiv za uporabo v kombinaciji z N(t)RTI samo pri tistih bolnikih, pri katerih je bilo protivirusno zdravljenje s shemo z NNRTI in N(t)RTI virološko neuspešno.
English: Given the increased etravirine exposure during pregnancy, caution should be applied for those pregnant patients that require concomitant medicinal products or have comorbidities that may further increase etravirine exposure.
Slovenian: Zaradi povečane izpostavljenosti etravirinu med nosečnostjo je pri nosečnicah, ki sočasno jemljejo druga zdravila ali imajo soobolenja, ki lahko še povečajo izpostavljenost etravirinu, potrebna previdnost.
English: INTELENCE tablet(s) should be taken orally, following a meal (see section 5.2).
Slovenian: Tableto(e) zdravila INTELENCE je treba vzeti peroralno, po obroku (glejte poglavje 5.2).
English: Etravirine is excreted in human milk.
Slovenian: Etravirin se izloča v materino mleko.
English: Experience in geriatric patients is limited: in the Phase III trials, 6 patients aged 65 years or older and 53 patients aged 56-64 years received etravirine.
Slovenian: Izkušnje z uporabo zdravila pri starejših so omejene: v preskušanjih III. faze je etravirin prejemalo 6 bolnikov, starih 65 let ali več, in 53 bolnikov, starih od 56 do 64 let.
English: CORTICOSTEROIDS Dexamethasone (systemic)
Slovenian: KORTIKOSTEROIDI deksametazon (sistemski)
English: Itraconazole Ketoconazole Posaconazole
Slovenian: itrakonazol ketokonazol posakonazol
English: Increased clinical and laboratory monitoring for HIV and HCV suppression is recommended.
Slovenian: Priporoča se večji klinični nadzor in spremljanje laboratorijskih parametrov glede zaviranja HIV in HCV.
English: Dose adjustments for these HMG Co-A reductase inhibitors may be necessary.
Slovenian: Za te zaviralce HMG Co-A reduktaze je lahko potrebna prilagoditev odmerka.
English: Etravirine is also a weak inhibitor of P-glycoprotein.
Slovenian: Etravirin je tudi šibek zaviralec P-glikoproteina.
English: INTELENCE is a medicine used for the treatment of Human Immunodeficiency Virus (HIV) infection.
Slovenian: Zdravilo INTELENCE uporabljamo za zdravljenje okužbe s humanim virusom imunske pomanjkljivosti (HIV).
English: The study enrolled patients on a stable but virologically failing antiretroviral treatment regimen, with a confirmed HIV-1 RNA plasma viral load ≥ 500 copies/ml.
Slovenian: V študijo so bili vključeni bolniki, ki so prejemali stabilen, vendar virološko neuspešen režim zdravljenja in s potrjenim HIV-1 RNK plazemskim virusnim bremenom ≥ 500 kopij/ml.
English: No human data on the effect of etravirine on fertility are available.
Slovenian: Ni podatkov o vplivu etravirina na plodnost pri človeku.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV disease and/or long-term exposure to CART.
Slovenian: Čeprav menijo, da v etiologiji osteonekroze sodeluje več dejavnikov (na primer uporaba kortikosteroidov, uživanje alkohola, huda imunosupresija in večji indeks telesne mase), so poročali o primerih osteonekroze, še posebej pri bolnikih z napredovalo okužbo s HIV in/ali dolgotrajno izpostavljenostjo CART.
English: Tenofovir disoproxil 245 mg once daily tenofovir
Slovenian: tenofovirdizoproksilat 245 mg enkrat na dan tenofovir
English: Marketing Authorisation Holder Janssen-Cilag International NV, Turnhoutseweg 30, B-2340 Beerse, Belgium
Slovenian: Imetnik dovoljenja za promet z zdravilom Janssen-Cilag International NV, Turnhoutseweg 30, B-2340 Beerse, Belgija
English: INTELENCE should be used with caution in these patients (see also sections 4.4 and 5.2).
Slovenian: Pri teh bolnikih je potrebna previdnost pri uporabi zdravila INTELENCE (glejte tudi poglavji 4.4 in 5.2).
English: Treatment-experienced adult patients
Slovenian: Že zdravljeni odrasli bolniki
English: Not de novo ENF
Slovenian: ne de novo ENF
English: 6 cells/l.
Slovenian: 6 celic/l.
English: Conclusions regarding the relevance of particular mutations or mutational patterns are subject to change with additional data, and it is recommended to always consult current interpretation systems for analysing resistance test results.
Slovenian: Sklepi glede pomembnosti posameznih mutacij ali mutacijskih vzorcev se spreminjajo, ko so na voljo dodatni podatki, zato je priporočljivo, da pri analizi izvida preiskave za ugotavljanje odpornosti virusa na zdravilo vedno pogledate trenutno veljavni sistem interpretacije.
English: In clinical trials, the frequency, type and severity of adverse reactions in paediatric patients were comparable to those observed in adults.
Slovenian: V kliničnih študijah so bili glede pogostnosti, vrste in jakosti neželeni učinki pri pediatričnih bolnikih primerljivi z neželenimi učinki opaženimi pri odraslih.
English: How to take INTELENCE
Slovenian: Kako jemati zdravilo INTELENCE
English: The population pharmacokinetic estimates for etravirine AUC12h and C0h are summarised in the table below.
Slovenian: Populacijske farmakokinetične ocene AUC12h in C0h so povzete v spodnji preglednici.
English: INTELENCE tablets contain lactose.
Slovenian: Tablete zdravila INTELENCE vsebujejo laktozo.
English: Data from the DUET studies suggest that baseline fold change (FC) in EC50 to etravirine was a predictive factor of virologic outcome, with gradually decreasing responses observed above FC 3 and FC 13.
Slovenian: Podatki iz študij DUET kažejo, da je bila začetna vrednost FC v EC50 za etravirin napovedni dejavnik za virološki odziv, saj so opazili postopno upadanje odziva nad vrednostmi FC 3 in FC 13.
English: Following virologic failure of an etravirine-containing regimen it is not recommended to treat patients with efavirenz and/or nevirapine.
Slovenian: Po ugotovljeni virološki neuspešnosti sheme zdravljenja z etravirinom ni priporočljivo, da bi bolnike zdravili z efavirenzom in/ali nevirapinom.
English: The pharmacokinetic properties of etravirine have been evaluated in adult healthy subjects and in adult and paediatric treatment-experienced HIV-1 infected patients.
Slovenian: Farmakokinetične lastnosti etravirina so ovrednotili pri zdravih odraslih preiskovancih in pri že zdravljenih odraslih in pediatričnih bolnikih, okuženih s HIV-1.
English: In most cases, INTELENCE can be combined with anti-HIV medicines belonging to another class.
Slovenian: V večini primerov lahko zdravilo INTELENCE kombiniramo z zdravili proti HIV iz drugih skupin,
English: At week 48, 53.5% of all paediatric patients had a confirmed undetectable viral load < 50 HIV-1 RNA copies/ml according to the TLOVR algorithm.
Slovenian: V 48. tednu je imelo 53,5% vseh pediatričnih bolnikov doseženo potrjeno nezaznavno virusno breme < 50 HIV-1 RNK kopij/ml po algoritmu TLOVR.
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterial infections and Pneumocystis jiroveci pneumonia.
Slovenian: Med pomembnejše primere sodijo citomegalovirusni retinitis, generalizirane in/ali žariščne mikobakterijske okužbe in pljučnica povzročena s Pneumocystis jirovecii.
English: The pharmacokinetics of etravirine have not been studied in patients with renal insufficiency.
Slovenian: Farmakokinetike etravirina niso proučevali pri bolnikih z ledvično insuficienco.
English: Confidence interval around observed difference of response rates; P-value = 0.0408.
Slovenian: Interval zaupanja z obeh strani opažene razlike v stopnjah odziva; p-vrednost = 0,0408
English: Etravirine N = 101
Slovenian: parameter etravirin N = 101
English: How to store INTELENCE Contents of the pack and other information
Slovenian: Shranjevanje zdravila INTELENCE Vsebina pakiranja in dodatne informacije
English: Co-administration is contraindicated (see section 4.3).
Slovenian: Sočasna uporaba je kontraindicirana (glejte poglavje 4.3)
English: It is believed that these symptoms are due to an improvement in the body's immune response, enabling the body to fight infections that may have been present with no obvious symptoms.
Slovenian: Menijo, da se ti simptomi in znaki pojavijo zaradi izboljšanja imunskega odziva, ki telesu omogoči borbo proti okužbam, ki so bile prej prikrite.
English: In a postmarketing retrospective cohort study aiming at substantiating the long-term safety profile of etravirine in HIV-1-infected children and adolescents receiving etravirine with other HIV-1 antiretrovirals (N = 182), Stevens-Johnson Syndrome was reported at a higher incidence (1%) than has been reported in adult clinical trials (<0.1%).
Slovenian: V postmarketinški retrospektivni kohortni študiji varnostnega profila etravirina pri otrocih in mladostnikih z okužbo z virusom HIV-1, ki so prejemali etravirin skupaj z drugimi protiretrovirusnimi zdravili proti virusu HIV-1 (N = 182), so o Stevens-Johnsonovem sindromu poročali z večjo incidenco (1%) kot v kliničnih študijah pri odraslih (< 0,1%).
English: Etravirine retains activity against HIV-1 viral strains resistant to nucleoside reverse transcriptase and/or protease inhibitors.
Slovenian: Etravirin je ohranil tudi delovanje proti virusnim sevom HIV-1, ki so odporni za zaviralce nukleozidne reverzne transkriptaze in/ali zaviralce proteaze.
English: Etravirine is primarily metabolised and eliminated by the liver and highly bound to plasma proteins.
Slovenian: Etravirin se presnavlja in izloča predvsem preko jeter in je v veliki meri vezan na plazemske beljakovine.
English: Interactions between etravirine and co-administered medicinal products are listed in table 1 (increase is indicated as “↑”, decrease as “↓”, no change as “↔”, not done as “ND”, confidence interval as “CI”).
Slovenian: Medsebojno delovanje med etravirinom in drugimi sočasno uporabljenimi zdravili je navedeno v preglednici 1 (zvečanje je označeno z “↑”, zmanjšanje z “↓”, stanje brez sprememb z “↔”, ni bilo opravljeno z “ND”, interval zaupanja z “CI”).
English: Rifabutin 300 mg once daily
Slovenian: rifabutin 300 mg enkrat na dan
English: The most frequent (incidence ≥ 10%) adverse reactions of all intensities reported for etravirine were rash, diarrhoea, nausea and headache.
Slovenian: Najbolj pogosti (incidenca ≥ 10%) neželeni učinki vseh jakosti, o katerih so poročali pri uporabi etravirina, so bili izpuščaj, driska, navzea in glavobol.
English: Caution should be observed in such patients, especially in case of history of a severe cutaneous drug reaction.
Slovenian: Pri takšnih bolnikih je potrebna previdnost, še posebej če imajo v anamnezi hude kožne reakcije na zdravila.
English: As etravirine is highly bound to plasma proteins, it is unlikely that it will be significantly removed by haemodialysis or peritoneal dialysis (see section 4.2).
Slovenian: Ker je etravirin v velikem odstotku vezan na plazemske beljakovine, je malo verjetno, da se bo pri hemodializi ali peritonealni dializi bistveno odstranjeval iz telesa (glejte poglavje 4.2).
English: Virologic parameters
Slovenian: Virološki parametri
English: Table 6:
Slovenian: Preglednica 6:
English: Medicinal products that affect etravirine exposure
Slovenian: Zdravila, ki vplivajo na stopnjo izpostavljenosti etravirinu