FrancophonIA/ELRC3.0 huggingface dataset:
English: The peak plasma concentrations at steady state of aclidinium and formoterol observed in patients with COPD treated with Duaklir Genuair twice daily for 5 days were reached within 5 minutes post-inhalation and were 128 pg/ml and 17 pg/ml, respectively.
Danish: De maksimale plasmakoncentrationer ved steady state af aclidinium og formoterol observeret hos patienter med KOL behandlet med Duaklir Genuair to gange dagligt i 5 dage blev nået inden for 5 minutter efter inhalationen og var henholdsvis 128 pg/ml og 17 pg/ml.
English: Co-administration of Duaklir Genuair with other anticholinergic and/or long-acting β2-adrenergic agonist containing medicinal products has not been studied and is not recommended.
Danish: Samtidig administration af Duaklir Genuair og andre antikolinerge og/eller langtidsvirkende lægemidler, der indeholder β2-adrenerg agonist, er ikke blevet undersøgt og anbefales ikke.
English: Duaklir Genuair should be used with caution in patients with severe cardiovascular disorders, convulsive disorders, thyrotoxicosis and phaeochromocytoma.
Danish: Duaklir Genuair bør anvendes med forsigtighed hos patienter med alvorlige hjerte-karsygdomme, krampesygdomme, thyrotoksikose og fæokromocytom.
English: If you use more Duaklir Genuair than you should If you think you may have used more Duaklir Genuair than you should, you are more likely to experience some of its side effects, such as blurred vision, dry mouth, feeling sick, shaking/tremor, headache, palpitations or an increase in blood pressure, therefore you must immediately contact your doctor or go to the nearest emergency unit.
Danish: Hvis du mener, at du muligvis har brugt mere Duaklir Genuair end du burde, vil du være mere tilbøjelig til at opleve nogle af dens bivirkninger, såsom sløret syn, tør mund, kvalme, rysten/tremor, hovedpine, hjertebanken eller en stigning i blodtrykket, og du skal derfor straks kontakte din læge eller tage på skadestue.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Duaklir Genuair in all subsets of the paediatric population in COPD (see section 4.2 for information on paediatric use).
Danish: Det Europæiske Lægemiddelagentur har dispenseret fra kravet om at fremlægge resultaterne af studier med Duaklir Genuair i alle undergrupper af den pædiatriske population med KOL (se pkt.
English: The frequencies assigned to the adverse reactions are based on crude incidence rates observed with Duaklir Genuair 340 micrograms /12 micrograms in the pooled analysis of randomised, placebo-controlled Phase III clinical studies of at least six months duration, or on experience with individual components.
Danish: De hyppigheder, der tildeles bivirkningerne, er baseret på rå incidensrater observeret med Duaklir Genuair 340 mikrogram/12 mikrogram i den poolede analyse af randomiserede, placebokontrollerede kliniske fase III-studier af mindst seks måneders varighed eller på erfaring med enkeltstofferne.
English: Dry mouth has been observed with medicines like Duaklir Genuair.
Danish: Der er observeret tør mund med lægemidler som Duaklir Genuair.
English: FEV1 at 1 hour post-dose and trough FEV1 (compared to aclidinium 400 micrograms and formoterol 12 micrograms, respectively) were defined as co-primary endpoints in both 6-month pivotal Phase III studies to demonstrate the bronchodilator contributions of formoterol and aclidinium in Duaklir Genuair, respectively.
Danish: FEV1 1 time efter dosis og trough FEV1 (sammenlignet med henholdsvis aclidinium 400 mikrogram og formoterol 12 mikrogram) blev defineret som co-primære endepunkter i begge 6-måneders pivotale fase III-studier for at påvise henholdsvis formoterols og aclidiniums bronkodilaterende bidrag i Duaklir Genuair.
English: Duaklir Genuair demonstrated a rapid onset of action within 5 minutes of the first inhalation relative to placebo (p<0.0001).
Danish: Duaklir Genuair viste hurtig virkning, inden for 5 minutter efter første inhalation i forhold til placebo (p<0,0001).
English: Duaklir Genuair is indicated as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD).
Danish: Duaklir Genuair er indiceret som bronkodilaterende vedligeholdelsesbehandling til lindring af symptomer hos voksne patienter med kronisk obstruktiv lungesygdom (KOL)
English: If you forget to use Duaklir Genuair
Danish: Hvis du har glemt at bruge Duaklir Genuair
English: In addition, Duaklir Genuair statistically significantly delayed the time to first moderate or severe exacerbation compared to placebo (hazard ratio=0.70; p=0.027).
Danish: Duaklir Genuair forsinkede desuden på statistisk signifikant vis tiden til første moderate eller svære eksacerbation sammenlignet med placebo (risikoforhold=0,70; p=0,027).
English: No clinically relevant effects of Duaklir Genuair on ECG parameters (including QT-interval) compared with aclidinium, formoterol and placebo were seen in Phase III studies of 6 to 12 months duration conducted in approximately 4,000 patients with COPD.
Danish: Der sås ingen klinisk relevant effekt af Duaklir Genuair på EKG-parametre (herunder QT-interval) sammenlignet med aclidinium, formoterol og placebo i fase III-studier med 6 til 12 måneders varighed gennemført hos cirka 4.000 patienter med KOL.
English: - develop tightness of the chest, coughing, wheezing or breathlessness immediately after using the medicine.
Danish: - udvikler trykken for brystet, hoste, hvæsende vejrtrækning eller kortåndethed umiddelbart efter brug af lægemidlet.
English: The onset of action of Duaklir Genuair was comparable to the effect of the fastacting β2-agonist formoterol 12 micrograms.
Danish: Duaklir Genuair viste virkning på samme måde som den hurtigt virkende β2-agonist formoterol 12 mikrogram.
English: Clinical efficacy studies showed that Duaklir Genuair provides clinically meaningful improvements in lung function (as measured by the forced expiratory volume in 1 second [FEV1]) over 12 hours following administration.
Danish: Kliniske studier viser, at Duaklir Genuair medfører klinisk relevante forbedringer i lungefunktion (målt ved forceret ekspiratorisk volumen på 1 sekund [FEV1]) over 12 timer efter administration.
English: Rare (may affect up to 1 in 1,000 people) - Sudden difficulty in breathing or swallowing, swelling of the tongue, throat, lips or face, skin rash and/or itching - these may be signs of an allergic reaction
Danish: Sjælden (kan forekomme hos op 1 ud af 1.000 mennesker) - Pludselige vanskeligheder med at trække vejret eller synke, hævelse af tunge, hals, læber eller ansigt, hududslæt og/eller kløe - dette kan være tegn på en allergisk reaktion
English: Pooled efficacy analysis of the two 6-month Phase III studies demonstrated a statistically significant reduction of 29% in the rate of moderate or severe exacerbations (requiring treatment with antibiotics or corticosteroids or resulting in hospitalisations) with Duaklir Genuair compared to placebo (rates per patient per year: 0.29 vs. 0.42, respectively; p=0.036).
Danish: Samlet effektanalyse af de to 6-måneders fase III-studier viste en statistisk signifikant reduktion på 29 % i antallet af moderate eller svære eksacerbationer (som krævede behandling med antibiotika eller kortikosteroider eller resulterede i hospitalsindlæggelser) ved Duaklir Genuair sammenlignet med placebo (hyppighed per patient per år: hhv. 0,29 vs. 0,42; p=0,036).
English: Following inhalation of a single dose of Duaklir Genuair 340/12 micrograms, aclidinium and formoterol were rapidly absorbed into plasma, reaching peak plasma concentrations within 5 minutes of inhalation in healthy subjects and within 24 minutes of inhalation in patients with COPD.
Danish: Efter inhalation af en enkelt dosis Duaklir Genuair 340/12 mikrogram blev aclidinium og formoterol hurtigt absorberet i plasma og nåede en maksimal plasmakoncentration inden for 5 minutter efter inhalation hos raske forsøgspersoner og inden for 24 minutter efter inhalation hos patienter med KOL.
English: Patients with a myocardial infarction during the previous 6 months, unstable angina, newly diagnosed arrhythmia within the previous 3 months, QTc (Bazett's method) above 470 msec, or hospitalisation within the previous 12 months for heart failure functional classes III and IV as per the “New York Heart Association” were excluded from the clinical studies, therefore Duaklir Genuair should be used with caution in these patients groups.
Danish: Patienter med myokardieinfarkt i de foregående 6 måneder, ustabil angina, nyligt diagnosticeret arytmi inden for de forudgående 3 måneder, QTc (Bazetts metode) over 470 msek eller hospitalsindlæggelse inden for de forudgående 12 måneder for hjertesvigt af NYHA-funktionsklasse III og IV blev ekskluderet fra de kliniske studier.
English: Duaklir Genuair provided a clinically meaningful improvement in disease-specific health status (as assessed by the St. George's Respiratory Questionnaire [SGRQ]) in study AUGMENT, with an improvement in the SGRQ total score compared to placebo of -4.35 units (p<0.0001).
Danish: Duaklir Genuair udviste en klinisk relevant forbedring i sygdomsspecifik helbredsstatus (vurderet ud fra St. Georges Respiratory Questionnaire [SGRQ]) i AUGMENT-studiet med en forbedring af samlet SGRQ-score sammenlignet med placebo på -4,35 enheder (p <0,0001).
English: Duaklir Genuair also showed improvements in exercise endurance time compared to placebo after 8 weeks of treatment (55 seconds [95% CI=5.6, 104.8; p=0.0292]; baseline value: 456 seconds).
Danish: Duaklir Genuair viste også forbedringer i udholdenhed under motion i sammenligning med placebo efter 8 ugers behandling (55 sekunder [95 % CI=5,6, 104,8; p=0,0292]; baselineværdi: 456 sekunder).
English: The inhaler is supplied sealed in a protective aluminium laminate bag containing a silica gel desiccant sachet, placed in a cardboard carton.
Danish: Inhalatoren leveres forseglet i en beskyttende pose af aluminiumlaminat, som indeholder en lille pose med silicageltørremiddel, anbragt i en papkarton.
English: In study ACLIFORM-COPD, only a small decrease in SGRQ total score compared to placebo was observed due to an unexpectedly large placebo response (p=0.598) and the percentages of patients who achieved clinically meaningful improvements from baseline were 55.3% with Duaklir Genuair and 53.2% with placebo (p=0.669).
Danish: I studiet ACLIFORM-COPD observeredes der kun et lille fald i total SGRQ-score sammenlignet med placebo på grund af et uventet stort placebo-respons (p=0,598) og den procentvise andel af patienter, der opnåede klinisk betydningsfulde forbedringer i forhold til baseline var 55,3 % med Duaklir Genuair og 53,2 % med placebo (p=0,669).
English: After 4 weeks of treatment Duaklir Genuair implied improvement versus placebo in change from baseline in morning pre-dose (trough) FRC, the primary endpoint, but the difference was not statistically significant (-0.125 L; 95% CI=(-0.259, 0.010); p=0.069*).
Danish: Efter 4 ugers behandling viste Duaklir Genuair en forbedring versus placebo i ændring fra baseline i FRC om morgenen inden dosering, det primære endepunkt, men forskellen var ikke statistisk signifikant (-0,125 l; 95 % CI=(-0,259, 0,010); p=0,069*).
English: If you are not sure of how to use Duaklir Genuair, contact your doctor or pharmacist.
Danish: Er du i tvivl om, hvordan du skal bruge Duaklir Genuair, så spørg lægen eller apotekspersonalet.
English: Duaklir Genuair showed improvements compared to placebo in lung volumes at 2-3h post dose (FRC=-0.366 L [95% CI=-0.515, -0.216; p<0.0001]; residual volume [RV]=-0.465 L [95% CI=0.648, -0.281; p<0.0001] and inspiratory capacity [IC]= 0.293 L [95% CI=0.208, 0.378; p<0.0001]).
Danish: Duaklir Genuair viste forbedringer i sammenligning med placebo i lungevolumen 2-3 timer efter dosering (FRC=-0,366 l [95 % CI=0,515, -0,216; p<0,0001]; residualvolumen [RV]=-0,465 l [95 % CI=-0,648, -0,281; p<0,0001] og inspiratorisk kapacitet [IC]= 0,293 l [95 % CI=0,208, 0,378; p<0,0001]).
English: Duaklir Genuair reduced the use of rescue medication over 6 months compared to placebo (by 0.9 puffs per day [p<0.0001]), aclidinium (by 0.4 puffs/day [p<0.001]) and formoterol (by 0.2 puffs/day [p=0.062]).
Danish: Duaklir Genuair reducerede brugen af anfaldsmedicin over 6 måneder sammenlignet med placebo (med 0,9 pust per dag [p<0,0001]), aclidinium (0,4 pust/dag [p <0,001]) og formoterol (med 0,2 pust/dag [p=0,062]).
English: • Any medicines that may be similar to Duaklir Genuair to treat breathing difficulties.
Danish: • Medicin til behandling af vejrtrækningsproblemer, som kan svare til Duaklir Genuair.
English: In the pooled analysis of these two studies, Duaklir Genuair showed greater improvements in SGRQ total score compared to formoterol (-1.7 units; p=0.018) or aclidinium (-0.79 units, p=0.273).
Danish: I den samlede analyse af disse to studier udviste Duaklir Genuair større forbedringer i SGRQ-totalscore sammenlignet med formoterol (-1,7 enheder; p=0,018) eller aclidinium (-0,79 enheder, p=0,273).
English: Duaklir Genuair provided a clinically meaningful improvement in breathlessness (assessed by the Transition Dyspnoea Index [TDI]) with an improvement in the TDI focal score at 6 months compared to placebo of 1.29 units in study ACLIFORM-COPD (p<0.0001) and 1.44 units in study AUGMENT (p<0.0001).
Danish: Duaklir Genuair førte til klinisk relevante forbedringer i kortåndethed (vurderet vha. Transition Dyspnoea Index [TDI]) med en forbedring i TDI fokalscore efter 6 måneder sammenlignet med placebo på 1,29 enheder i studiet ACLIFORM-COPD (p<0,0001) og 1,44 enheder i studiet AUGMENT (p<0,0001).
English: After 4 weeks of treatment, Duaklir Genuair improved the number of steps per day compared to placebo (731 steps/day; 95% CI=279, 1181; p=0.0016) and reduced the percentage of inactive patients (<6000 steps per day) [40.8% compared to 54.5%; p<0.0001].
Danish: Efter 4 ugers behandling forbedrede Duaklir Genuair antallet af skridt pr. dag i sammenligning med placebo (731 skridt pr. dag; 95 % CI=279, 1181; p=0,0016) og reducerede procentdelen af inaktive patienter (<6000 skridt pr. dag) [40,8 % sammenlignet med 54,5 %; p<0,0001].
English: The number of steps/day in the Duaklir Genuair treatment group was maintained resulting in a treatment effect compared to placebo of 510 steps/day (p=0.1588) and a reduction versus placebo in the percentage of inactive patients (<6000 steps per day) (41.5% compared to 50.4%; p=0.1134).
Danish: Antallet af skridt pr. dag i Duaklir Genuair-behandlingsgruppen blev opretholdt, hvilket resulterede i en behandlingseffekt sammenlignet med placebo på 510 skridt pr. dag (p=0,1588) og en reduktion versus placbo i procentdelen af inaktive patienter (<6000 skridt pr. dag) (41,5 % sammenlignet med 50,4 %; p=0,1134).
English: What Duaklir Genuair contains - The active substances are aclidinium and formoterol fumarate dihydrate.
Danish: Duaklir Genuair indeholder: - Aktive stoffer: Aclidinium og formoterolfumaratdihydrat.
English: The percentage of patients in AUGMENT who achieved a clinically meaningful improvement from baseline in SGRQ total score (defined as a decrease of at least 4 units) was higher with Duaklir Genuair than with placebo (58.2% compared to 38.7%, respectively; p<0.001).
Danish: Procentdelen af patienter i AUGMENT som opnåede en klinisk relevant forbedring i forhold til baseline i SGRQ-totalscore (defineret som et fald på mindst 4 enheder) var højere med Duaklir Genuair end med placebo (henholdsvis 58,2 % sammenlignet med 38,7 %, p <0,001 ).
English: Duaklir Genuair has no or negligible influence on the ability to drive and use machines.
Danish: Duaklir Genuair påvirker ikke eller kun i ubetydelig grad evnen til at føre motorkøretøj og betjene maskiner.
English: Duaklir Genuair 340 micrograms /12 micrograms inhalation powder
Danish: Duaklir Genuair 340 mikrogram/12 mikrogram inhalationspulver
English: The percentages of patients with clinically meaningful improvements in TDI focal score (defined as an increase of at least 1 unit) were higher with Duaklir Genuair than with placebo in ACLIFORM-COPD (64.8% compared to 45.5%; p<0.001) and AUGMENT (58.1% compared to 36.6%; p<0.0001).
Danish: Procentdelene af patienter med klinisk relevante forbedringer i TDI fokalscore (defineret som en stigning på mindst 1 enhed) var højere med Duaklir Genuair end med placebo i ACLIFORM-COPD (64,8 % sammenlignet med 45,5 %; p<0,001) og AUGMENT (58,1 % sammenlignet med 36,6 %; p<0,0001).
English: What you need to know before you use Duaklir Genuair
Danish: Det skal du vide, før du begynder at bruge Duaklir Genuair
English: The pooled analysis of these two studies showed Duaklir Genuair to be associated with statistically significantly greater improvements in TDI focal score compared to aclidinium (0.4 units, p=0.016) or formoterol (0.5 units, p=0.009).
Danish: Den samlede analyse af disse to studier viste, at Duaklir Genuair er forbundet med statistisk signifikant større forbedringer af TDI-fokalscore sammenlignet med aclidinium (0,4 enheder, p=0,016) eller formoterol (0,5 enheder, p=0,009).
English: In study ACLIFORM-COPD, Duaklir Genuair showed improvements in FEV1 at 1 hour post-dose relative to placebo and aclidinium of 299 ml and 125 ml, respectively (both p<0.0001) and improvements in trough FEV1 relative to placebo and formoterol of 143 ml and 85 ml, respectively (both p<0.0001).
Danish: I studiet ACLIFORM-COPD viste Duaklir Genuair forbedringer i FEV1 1 time efter dosis i forhold til placebo and aclidinium med henholdsvis 299 ml og 125 ml (begge p<0,0001) og forbedrede trough FEV1 i forhold til placebo og formoterol med henholdsvis 143 ml og 85 ml (begge p<0,0001).
English: What Duaklir Genuair looks like and contents of the pack Duaklir Genuair is a white or almost white inhalation powder.
Danish: Duaklir Genuair er et hvidt eller næsten hvidt inhalationspulver.
English: In addition, a higher percentage of patients receiving Duaklir Genuair responded with a clinically meaningful improvement in TDI focal score compared to either aclidinium or formoterol (61.9% compared to 55.7% and 57.0%, respectively; p=0.056 and p=0.100, respectively).
Danish: En større procentdel af patienter, som fik Duaklir Genuair, responderede desuden med en klinisk relevant forbedring i TDI-fokalscore i forhold til enten aclidinium eller formoterol (61,9 % sammenlignet med henholdsvis 55,7 % og 57,0 %, henholdsvis p=0,056 og p=0,100).
English: In addition, a higher percentage of patients receiving Duaklir Genuair responded with a clinically meaningful improvement in SGRQ total score compared to aclidinium and formoterol (56.6% compared to 53.9% and 52.2%, respectively; p=0.603 and p=0.270, respectively).
Danish: En større procentdel af patienter, som fik Duaklir Genuair, responderede desuden med en klinisk relevant forbedring i SGRQ-totalscore i forhold til aclidinium og formoterol (56,6 % sammenlignet med henholdsvis 53,9 % og 52,2 %, henholdsvis p=0,603 og p=0,270).
English: MANUFACTURER RESPONSIBLE FOR BATCH RELEASE
Danish: A. FREMSTILLER ANDSVARLIG FOR BATCHFRIGIVELSE
English: In study AUGMENT, Duaklir Genuair showed improvements in FEV1 at 1 hour post-dose relative to placebo and aclidinium of 284 ml and 108 ml (both p<0.0001), respectively, and improvements in trough FEV1 relative to placebo and formoterol of 130 ml (p<0.0001) and 45 ml (p=0.01), respectively.
Danish: I studiet AUGMENT udviste Duaklir Genuair forbedringer i FEV1 1 time efter dosis i forhold til placebo og aclidinium med henholdsvis 284 ml and 108 ml, (begge p<0,0001) og forbedrede trough FEV1 i forhold til placebo og formoterol med henholdsvis 130 ml (p<0,0001) og 45 ml (p=0,01).
English: Following repeated inhalations of Duaklir Genuair 340/12 micrograms, the systemic exposure of aclidinium and formoterol, as measured by AUC, is similar in Japanese and Caucasian patients.
Danish: Den systemiske eksponering for aclidinium og formoterol, målt via AUC, er ens hos japanske og kaukasiske patienter efter gentagne inhalationer med Duaklir Genuair 340/12 mikrogram.
English: - The effects of Duaklir Genuair last for 12 hours; therefore, you should try to use Duaklir Genuair at the same time each morning and evening as this will ensure that there is always enough medicine in your body to help you breathe more easily throughout the day and night.
Danish: Det garanterer, at der altid er tilstrækkelig medicin i din krop til at hjælpe dig med at trække vejret lettere hele dagen og natten.
English: Manufacturer: Industrias Farmacéuticas Almirall, S.A.
Danish: Navn og adresse på den fremstiller, der er ansvarlig for batchfrigivelse Industrias Farmacéuticas Almirall, S.A.
English: Following inhalation of Duaklir Genuair 340/12 micrograms, with plasma sampling up to 24 hours post-dose, the terminal elimination half-life observed for aclidinium bromide ranged from 11-33 hours and for formoterol from 12-18 hours.
Danish: Den terminale eliminationshalveringstid observeret for aclidiniumbromid spændte mellem 11-33 timer og for formoterol mellem 12-18 timer efter inhalation af Duaklir Genuair 340/12 mikrogram, med plasmaprøver op til 24 timer efter administration.
English: Uncommon - Fast heart beat (tachycardia) - Chest pain or tightness in the chest (angina pectoris) - Blurred vision - Changes in the sound of the voice (dysphonia) - Difficulty passing urine or a feeling that your bladder has not completely emptied (urinary retention) - An abnormal heart trace (QT interval prolongation) potentially leading to an abnormal heart rhythm - Distorted sense of taste (dysgeusia) - Throat irritation - Inflammation of the mouth (stomatitis) - Increased blood pressure - Agitation - Rash - Itching of the skin
Danish: Ikke almindelig - Hurtig puls (takykardi) - Brystsmerter eller trykken for brystet (angina pectoris) - Sløret syn - Ændringer i stemmelyden (dysfoni) - Vandladningsbesvær eller en følelse af, at din blære ikke er helt tømt (urinretention)
English: Hepatic impairment No dose adjustments are required in patients with hepatic impairment (see section 5.2).
Danish: Nedsat leverfunktion Det er ikke nødvendigt at justere dosis hos patienter med nedsat leverfunktion (se pkt.
English: Duaklir Genuair should not be used in asthma; clinical studies of Duaklir Genuair in asthma have not been conducted.
Danish: Der er ikke foretaget kliniske studier med Duaklir Genuair ved astma.
English: Duaklir Genuair 340 micrograms/12 micrograms inhalation powder aclidinium/formoterol fumarate dihydrate
Danish: Duaklir Genuair 340 mikrogram/12 mikrogram inhalationspulver aclidinium/formoterolfumaratdihydrat
English: If you stop using Duaklir Genuair
Danish: Hvis du har brugt for meget Duaklir Genuair
English: How to use Duaklir Genuair
Danish: Sådan skal du bruge Duaklir Genuair
English: Renal impairment No dose adjustments are required in patients with renal impairment (see section 5.2).
Danish: Nedsat nyrefunktion Det er ikke nødvendigt at justere dosis hos patienter med nedsat nyrefunktion (se pkt.
English: COPD is a long-term disease; therefore, Duaklir Genuair is for long-term use.
Danish: Duaklir Genuair er derfor til langtidsbrug.
English: Duaklir Genuair 340 mcg/12 mcg inhalation powder aclidinium/formoterol fumarate dihydrate
Danish: Duaklir Genuair 340 mikrog/12 mikrog inhalationspulver aclidinium/formoterolfumaratdihydrat
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Danish: Brug af anden medicin sammen med Duaklir Genuair Fortæl det altid til lægen eller apotekspersonalet, hvis du tager anden medicin eller har gjort det for nylig.
English: - If you get sudden tightness of the chest, coughing, wheezing or breathlessness immediately after using the medicine.
Danish: Stop med at tage Duaklir Genuair og søg lægehjælp omgående, hvis du oplever noget af følgende: - Hvis du oplever pludselig trykken for brystet, hoste, hvæsende vejrtrækning eller kortåndethed umiddelbart efter brug af lægemidlet.
English: The following instructions should therefore be followed carefully.
Danish: Følgende instruktioner bør derfor følges omhyggeligt.
English: Milk: 5 days.
Danish: Mælk: 5 dage.
English: Wash the udder if it is dirty.
Danish: Vask yveret, hvis det er snavset.