FrancophonIA/ELRC3.0 huggingface dataset:
English: • reduced platelets number just after the infusion - this can be reversed, but can be fatal in b) If you are being treated for granulomatosis with polyangiitis or microscopic polyangiitis
Croatian: smanjenje broja bijelih krvnih stanica koje ne nastupa odmah smanjenje broja krvnih pločica neposredno nakon infuzije - može se povući, ali u rijetkim slučajevima može imati i smrtni ishod gubitak sluha, gubitak drugih osjeta b) Bolesnici koji se liječe od granulomatoze s poliangiitisom ili mikroskopskog poliangiitisa Vrlo česte nuspojave (mogu se javiti u više od 1 na 10 osoba):
English: Retreatment with rituximab
Croatian: Liječenje R-CHOP
English: The antigen is expressed on >95 % of
Croatian: ORR je iznosio 38 % (95 % CI
English: When you are treated with Rituzena in combination with chemotherapy, you will receive Rituzena every 28 days until you have received 6 doses.
Croatian: Lijek Rituzena primit ćete istoga dana kao i kemoterapiju, koja se obično daje do 8 puta u b) Bolesnici koji se liječe od kronične limfocitne leukemije Kada se liječite lijekom Rituzena u kombinaciji s kemoterapijom, primat ćete infuziju lijeka Rituzena svakih 28 dana sve dok ne primite ukupno 6 doza.
English: Cytokine release syndrome may be clinically indistinguishable
Croatian: Sindrom otpuštanja citokina možda se klinički neće moći razlikovati od akutnih reakcija preosjetljivosti.
English: • Weight loss
Croatian: CI: interval pouzdanosti
English: Premedication consisting of an analgesic/anti-pyretic medicinal product and an anti-histaminic medicinal product, should always be administered before each infusion of rituximab.
Croatian: Prije svake infuzije lijeka rituksimab uvijek se mora primijeniti premedikacija koja sadrži analgetik/antipiretik i antihistaminik.
English: Each mL of concentrate contains 10mg of rituximab.
Croatian: 1 ml sadrži 10 mg rituksimaba.
English: Rituzena 100 mg concentrate for solution for infusion Rituximab
Croatian: Rituzena 100 mg koncentrat za otopinu za infuziju rituksimab
English: • Warning on the risk of infections and PML, including the symptoms • The need for patients to contact their health care professional if symptoms occur
Croatian: • Upozorenje o riziku od infekcija i PML-a, uključujući simptome
English: Each vial contains 500 mg of rituximab.
Croatian: 1 bočica sadrži 500 mg rituksimaba.
English: (75%) and microscopic polyangiitis (24%) were enrolled and treated in an active-comparator, randomised, double-blind, multicentre, non-inferiority trial.
Croatian: dvostruko slijepom, multicentričnom, aktivnim lijekom kontroliranom ispitivanju neinferiornosti.
English: Each vial contains 100 mg of rituximab.
Croatian: 1 bočica sadrži 100 mg rituksimaba.
English: The incidence of ADRs of all grades and grade 3 /4 ADR was similar in elderly patients compared
Croatian: Stariji bolesnici (≥ 65 godina): Incidencija nuspojava svih stupnjeva i nuspojava stupnja 3/4 bila je slična u starijih i mlađih bolesnika
English: • blood clotting problems, decrease of red blood cell production and increase of red blood cell destruction (aplastic haemolytic anaemia), swollen or enlarged lymph nodes
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na 100 osoba): tegobe sa zgrušavanjem krvi, smanjeno stvaranje crvenih krvnih stanica i pojačano uništavanje crvenih krvnih stanica (aplastična hemolitička anemija), otečeni ili povećani neraspoloženost i gubitak interesa ili zadovoljstva u obavljanju aktivnosti, nervoza tegobe s osjetom okusa - poput promjena u okusu srčane tegobe - kao što su usporeno kucanje srca ili bol u prsnom košu (angina)
English: You may be asked not to take these other medicines 12 hours before you are given Rituzena.
Croatian: Karticu nosite sa sobom još 2 godine nakon što primite posljednju dozu lijeka Rituzena.
English: Body system Adverse reaction
Croatian: Organski sustav Nuspojava
English: Very common side effects (may affect more than 1 in 10 people): • infections, such as chest infections, urinary tract infections (pain on passing water), colds
Croatian: Vrlo rijetke nuspojave lijeka Rituzena (mogu se javiti u do 1 na 10 000 osoba): • stvaranje teških plikova po koži koji mogu ugroziti život.
English: What you need to know before you use Rituzena Do not take Rituzena if:
Croatian: U ovoj se kartici navodi što morate znati prije nego primite lijek Rituzena što trebate učiniti ako mislite da se
English: No data are
Croatian: Nema dostupnih podataka.
English: • low number of white blood cells sometimes with fever, or low number of blood cells called
Croatian: nizak broj bijelih krvnih stanica, ponekad s vrućicom, ili nizak broj krvnih pločica koje se mjesta na vlasištu bez kose, zimica, glavobolja oslabljen imunitet - posljedica niskih razina protutijela zvanih „imunoglobulini“ (IgG) u krvi; imunoglobulini pomažu u zaštiti od infekcije
English: Also some other medicines can
Croatian: Možda te lijekove nećete smjeti uzeti
English: Haematologic adverse reactions
Croatian: Hematološke toksičnosti
English: • swelling of the hands or ankles
Croatian: Na koži ili sluznicama,
English: Cases of hepatitis B reactivation, including those with a fatal outcome, have been reported in rheumatoid arthritis, granulomatosis with polyangiitis and microscopic polyangiitis patients receiving
Croatian: U bolesnika s reumatoidnim artritisom, granulomatozom s poliangiitisom i mikroskopskim poliangiitisom koji su primali rituksimab prijavljeni su slučajevi reaktivacije hepatitisa B, uključujući one sa smrtnim ishodom.
English: This is usually given b) If you are being treated for chronic lymphocytic leukaemia
Croatian: Tablica 5b Prva linija liječenja kronične limfocitne leukemije
English: Tell your doctor or nurse if you are taking or have previously taken medicines which
Croatian: Recite liječniku ili medicinskoj sestri ako uzimate ili ste ranije uzimali lijekove koji mogu utjecati na imunološki sustav, uključujući kemoterapiju.
English: • short term increase in the amount of some types of anti-bodies in the blood (called immunoglobulins - IgM), chemical disturbances in the blood caused by break-down of
Croatian: kratkotrajno povišenje količine nekih vrsta protutijela u krvi (imunoglobulina - IgM), kemijski poremećaji krvi uzrokovani raspadanjem umirućih stanica raka oštećenje živaca u rukama i nogama, paraliza lica upale krvnih žila, uključujući one koje izazivaju kožne simptome oštećenje stijenke crijeva (perforacija) teški problemi s kožom uz stvaranje mjehurića na koži koji mogu biti opasni po život.
English: • feeling dizzy
Croatian: Razine IgG-a
English: Treatment difference (Rituximab --cyclophosphamide)
Croatian: (rituksimabciklofosfamid)
English: Pneumocystis jirovecii
Croatian: Hematološke nuspojave
English: Cough
Croatian: KLL-a
English: A small number of cases of hepatitis B reactivation, some with fatal outcome, have been reported in granulomatosis with polyangiitis and microscopic polyangiitis patients receiving rituximab in the post
Croatian: Incidencija zloćudnih bolesti u bolesnika liječenih rituksimabom u kliničkom ispitivanju u indikacijama granulomatoze s poliangiitisom i mikroskopskog poliangiitisa iznosila je 2,00 na
English: • pain in the muscles or in the hands or feet • low number of red blood cells (anaemia)
Croatian: probavne tegobe zatvor kožni osip, uključujući akne ili mrlje navale crvenila ili crvenilo kože začepljen nos napeti ili bolni mišići bol u mišićima ili u šakama ili stopalima nizak broj crvenih krvnih stanica (anemija)
English: Severe skin reactions such as Toxic Epidermal Necrolysis (Lyell's Syndrome) and Stevens-Johnson Syndrome, some with fatal outcome, have been reported (see section 4.8).
Croatian: Prijavljene su teške kožne reakcije poput toksične epidermalne nekrolize (Lyellov sindrom) i Stevens
English: • tight or painful muscles
Croatian: Poremećaji mišićno-koštanog sustava
English: Detailed information on this medicine is available on the European Medicines Agency web site:
Croatian: Za sve informacije o ovom lijeku obratite se lokalnom predstavniku nositelja odobrenja za stavljanje lijeka u promet:
English: increased LDH, hypocalcaemia
Croatian: Poremećaji metabolizm a i prehrane hipokalcijemija
English: See the end of section 4
Croatian: vidjeti dio 4.4
English: Clinical experience in granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis A total of 197 patients aged 15 years or older with severely, active granulomatosis with polyangiitis
Croatian: Ukupno je 197 bolesnika u dobi od 15 ili više godina s teškom aktivnom granulomatozom s poliangiitisom (75 %) i mikroskopskim poliangiitisom (24 %) sudjelovalo i liječeno u randomiziranom,
English: There was no increased rate in overall infections or serious infections in
Croatian: U bolesnika s niskim vrijednostima IgA, IgG ili IgM nije porasla stopa ukupnih infekcija niti ozbiljnih infekcija.
English: severe cardiac disoders4 and 6
Croatian: Poremećaji bubrega i mokraćnog sustava zatajenje bubrega4
English: If you are being treated for granulomatosis with polyangiitis or microscopic polyangiitis
Croatian: U kliničkom ispitivanju kod granulomatoze s poliangiitisom i mikroskopskog poliangiitisa
English: The most frequent reported or observed serious adverse drug reactions were:  IRRs (including cytokine-release syndrome, tumour-lysis syndrome), see section 4.4.
Croatian: • reakcije povezane s infuzijom (uključujući sindrom otpuštanja citokina i sindrom lize tumora),
English: If you do not follow all of these instructions,
Croatian: Ako ne budete slijedili sve ove upute,
English: • You drink alcohol - especially when you have not eaten much.
Croatian: • pijete alkohol - osobito kada niste mnogo pojeli
English: Be especially aware of the following:
Croatian: Osobito pripazite na sljedeće:
English: This must always be treated by a doctor, normally in a hospital.
Croatian: Njih uvijek mora liječiti liječnik, obično u bolnici.
English: • Sugar (at least 20 grams).
Croatian: • šećer (barem 20 grama)
English: • Any health risks in the countries you will visit.
Croatian: • mogućim zdravstvenim rizicima u zemljama koje ćete posjetiti
English: The end of the observation period was 36 hours.
Croatian: Razdoblje promatranja završilo je nakon 36 sati.
English: From week 9 to end of study period
Croatian: Od 9. tjedna do kraja razdoblja ispitivanja
English: Ask your doctor whether you can drive if:
Croatian: Pitajte svog liječnika možete li voziti:
English: ATC Code: A10A E04.
Croatian: ATK oznaka: A10A E04.
English: • How much Toujeo you need each day and at what time.
Croatian: • koliko lijeka Toujeo trebate primijeniti svaki dan i u koje vrijeme
English: Do not leave your insulin in a car on an exceptionally warm or cold day.
Croatian: Nemojte ostavljati inzulin u automobilu kada je izrazito topao ili hladan dan.
English: • You are doing less exercise than usual.
Croatian: • vježbate manje nego obično
English: You may need to talk about:
Croatian: Možda ćete morati porazgovarati o sljedećem:
English: Tell a doctor straight away if you notice signs of a severe allergic reaction.
Croatian: Odmah se javite liječniku ako primijetite znakove teške alergijske reakcije.
English: The educational materials consist of:
Croatian: Edukacijski se materijali sastoje od:
English: Never share your pen - it is only for you.
Croatian: Nikada nemojte dijeliti svoju brizgalici s drugima - ona je namijenjena samo Vama.
English: • When you may need a higher or lower dose.
Croatian: • kada bi Vam mogla biti potrebna veća ili manja doza
English: Component of a multipack, can't be sold separately.
Croatian: Komponenta višestrukog pakiranja, ne može se prodavati zasebno.
English: This is especially important if you have other injector pens.
Croatian: Ovo je osobito važno ako koristite i druge injekcijske brizgalice.
English: These signs often develop before the signs of a low sugar level in the brain.
Croatian: Ovi se znakovi obično razvijaju prije znakova niske razine šećera u mozgu.
English: • What you should do in an emergency situation if you feel unwell or become ill.
Croatian: • što trebate učiniti u hitnim slučajevima ako se ne osjećate dobro ili obolite
English: If the hypoglycaemia comes back again, take another 10 to 20 grams of sugar.
Croatian: Ako hipoglikemija ponovno nastupi, uzmite još 10-20 g šećera.
English: This may constitute a risk in situations where these abilities are of special importance (e.g. driving a car or using machines).
Croatian: To može predstavljati rizik u situacijama u kojima su takve sposobnosti posebno važne (npr. vožnja ili rad sa strojevima).
English: Generally, the greater and more rapid the decline in blood glucose, the more marked is the phenomenon of counter-regulation and its symptoms.
Croatian: Općenito, što je veći i brži pad razine glukoze u krvi, to su izraženiji fenomen proturegulacije i njegovi simptomi.
English: The first signs may be in your body generally.
Croatian: Prvi se znakovi mogu pojaviti u cijelom tijelu.
English: • You are doing more exercise than usual or a different type of physical activity.
Croatian: • vježbate više nego obično ili se bavite drugom vrstom tjelesne aktivnosti
English: You may dial the wrong dose.
Croatian: Tako možete izabrati krivu dozu.
English: Please, consult your doctor for further information.
Croatian: Obratite se svom liječniku za više informacija.
English: The target audience and the modalities for distribution of all of these materials are to be agreed at Member State Level.
Croatian: Ciljane skupine i način distribucije svih ovih materijala dogovorit će se na razini države članice.
English: Date of first authorisation: 27 June 2000 Date of latest renewal: 17 February 2015
Croatian: Datum posljednje obnove: 17. veljače 2015.
English: • Guide for healthcare professionals
Croatian: • Vodiča za zdravstvene djelatnike
English: • You have a certain type of nervous disease (called “diabetic autonomic neuropathy”).
Croatian: • ako bolujete od određene vrste neurološke bolesti (koja se naziva 'dijabetička autonomna neuropatija')
English: • You have an injury, infection or fever or have had an operation.
Croatian: • imate ozljedu, infekciju ili vrućicu ili ste bili na operaciji
English: Discard the pen after this time period.
Croatian: Bacite brizgalicu nakon tog razdoblja.
English: Toujeo DoubleStar 24 months.
Croatian: Toujeo DoubleStar 24 mjeseca.
English: These injections should be given even if it is not certain that you have hypoglycaemia.
Croatian: Te injekcije treba primijeniti čak i onda kada nije sigurno da imate hipoglikemiju.
English: Needles must be discarded immediately after use.
Croatian: Igle se moraju baciti odmah nakon uporabe.
English: Do not stop using this medicine without talking to your doctor.
Croatian: Nemojte prestati primjenjivati ovaj lijek bez prethodnog razgovora s liječnikom.
English: • You are recovering from an injury, operation or other stress.
Croatian: • oporavljate se od ozljede, operacije ili nekog drugog stresa
English: • You are under stress - such as emotional distress or excitement.
Croatian: • pod stresom ste - emocionalno ste uznemireni ili uzbuđeni
English: Then eat something (such as bread or pasta) that will raise your blood sugar over a longer time.
Croatian: Zatim pojedite nešto (primjerice kruh ili tjesteninu) što će povisiti razinu šećera u krvi na dulje vrijeme.
English: It is used for once daily dosing.
Croatian: Primjenjuje se jedanput na dan.
English: Toujeo SoloStar 30 months.
Croatian: Toujeo SoloStar 30 mjeseci.
English: If you find it difficult to recognise your warning signs, you should avoid situations (such as driving a car) in which you or others would be put at risk by hypoglycaemia.
Croatian: Ako teško prepoznajete upozoravajuće znakove, izbjegavajte situacije (poput vožnje automobila) u kojima zbog hipoglikemije možete sebe ili druge izložiti riziku.
English: Always perform a safety test
Croatian: Uvijek napravite test sigurnosti.
English: Take about 10 to 20 grams sugar straight away - such as glucose, sugar cubes or a sugary-drink.
Croatian: Odmah uzmite približno 10-20 g šećera - npr. glukozu, kocke šećera ili napitak koji sadrži šećer.
English: • How to correctly store your insulin while travelling.
Croatian: • kako ispravno čuvati inzulin za vrijeme putovanja
English: • You are elderly.
Croatian: • ako ste starije dobi
English: • Throw the pen away and use a new one.
Croatian: • bacite brizgalicu i upotrijebite novu
English: STEP 3: Do a safety test
Croatian: 3. KORAK: Napravite test sigurnosti
English: • Pioglitazone.
Croatian: • pioglitazon.
English: DoubleStar) are not bioequivalent and are therefore not interchangeable without dose adjustment.
Croatian: DoubleStar) nisu bioekvivalentni i stoga nisu međusobno zamjenjivi bez prilagodbe doze.
English: The educational materials for healthcare professionals shall contain the following key elements:
Croatian: Edukacijski materijal za zdravstvene djelatnike sadržavat će sljedeće ključne elemente:
English: • If you cannot select your full prescribed dose, split the dose into two injections or use a new pen.
Croatian: • Ako ne možete odabrati cijelu propisanu dozu, podijelite je na dvije injekcije ili upotrijebite novu brizgalicu.
English: • If your type of insulin is available in the country you are visiting.
Croatian: • je li vrsta inzulina koju koristite dostupna u zemlji koju posjećujete
English: • Do not touch the injection button yet.
Croatian: • Nemojte još dirati dugme za injiciranje.
English: In most cases you will talk to a doctor.
Croatian: U većini ćete slučajeva razgovarati s liječnikom.
English: c Nocturnal hypoglycaemia: Episode that occurred between 00:00 and 05:59 hours d 6-month treatment period
Croatian: Noćna hipoglikemija: epizoda koja je nastupila između 00:00 i 05:59 sati d
English: • You miss meals or delay them.
Croatian: • preskačete ili odgađate obroke
English: What other people should do if you have hypoglycaemia
Croatian: Što drugi trebaju učiniti ako imate hipoglikemiju
English: E After holding and slowly counting to 5, release the injection button.
Croatian: Nakon što ste držeći dugme pritisnutim polako brojali do 5, otpustite dugme za injiciranje.
English: • You have recently had too low blood sugar (for example the day before).
Croatian: • ako ste nedavno imali prenisku razinu šećera u krvi (primjerice dan ranije)
English: • You do not eat enough, or eat food containing less sugar (carbohydrate) than normal - artificial sweeteners are not carbohydrates.
Croatian: • ne jedete dovoljno ili jedete hranu koja sadrži manje šećera (ugljikohidrata) nego obično umjetni zaslađivači nisu ugljikohidrati
English: The dose regimen (dose and timing) should be adjusted according to individual response.
Croatian: Režim doziranja (dozu i vrijeme primjene) treba prilagoditi odgovoru pojedinog bolesnika.
English: In most cases you will need to talk to a doctor.
Croatian: U većini ćete slučajeva morati razgovarati s liječnikom.
English: Glycaemic control was similar when Toujeo was administered once daily in the morning or in the evening.
Croatian: Regulacija glikemije bila je slična kada se Toujeo primjenjivao jedanput na dan ujutro ili navečer.
English: Speak to a doctor straight away if you are not able to control the hypoglycaemia, or it comes back again.
Croatian: Odmah razgovarajte s liječnikom ako ne možete kontrolirati hipoglikemiju ili ako se ona ponavlja.
English: Medication errors prevention
Croatian: Sprječavanje medikacijskih pogrešaka
English: Toujeo can be used in adolescents and children from the age of 6 years based on the same principles as for adult patients (see sections 5.1and 5.2).
Croatian: Toujeo mogu primjenjivati adolescenti i djeca od navršenih 6 godina nadalje na osnovi istih principa kao i odrasli bolesnici (vidjeti dijelove 5.1 i 5.2).
English: The scale on most syringes is made for non-concentrated insulin only.
Croatian: Skala na većini štrcaljki odnosi se samo na inzulin koji nije koncentriran.
English: • Changes in taste (dysgeusia).
Croatian: • promjena osjeta okusa (disgeuzija)
English: Based on your lifestyle, your blood sugar tests and your previous insulin use, your doctor will tell you:
Croatian: Na temelju Vašeg načina života, nalaza pretraga razine šećera u krvi te ranije uporabe inzulina, Vaš liječnik će Vam reći:
English: If they don't, the full dose might not be delivered.
Croatian: Ako ga ne naprave, možda se neće isporučiti cijela doza.
English: Tel: 800 13 12 12 (domande di tipo tecnico) +39 800 536389 (altre domande e chiamate dall'estero)
Croatian: Tel: 800 131212 (domande di tipo tecnico) 800 536389 (altre domande)
English: If you have “Type 1” diabetes and you have an illness or injury:
Croatian: Ako imate šećernu bolest tipa 1 te bolest ili ozljedu:
English: * You will not see the plunger until you have injected a few doses.
Croatian: * Klip se neće vidjeti dok ne injicirate nekoliko doza.
English: • Your blood sugar levels are almost normal or are unstable.
Croatian: • ako je razina šećera u krvi gotovo normalna ili nije stabilna
English: Before first use, the pen must be stored at room temperature at least 1 hour before use.
Croatian: Prije prve uporabe, brizgalica se mora držati na sobnoj temperaturi najmanje 1 sat.
English: • Instructions on how to report medication errors or adverse events: Details for national reporting added at country level.
Croatian: • Upute kako prijaviti medikacijske pogreške ili nuspojave: Pojedinosti nacionalnog sustava prijave dodaju se na razini države.
English: This could be dangerous to yourself and others.
Croatian: Mogu umanjiti i koncentraciju, što može biti opasno za Vas i druge.
English: Long term efficacy and safety outcome study
Croatian: Ispitivanje dugoročne djelotvornosti i sigurnosti
English: • Patient/carer guide (patient brochure)
Croatian: • Vodiča za bolesnika/skrbnika (brošura za bolesnika)
English: If you use a new pen, perform a safety test (see STEP 3).
Croatian: Ako upotrijebite novu brizgalicu, napravite test sigurnosti (vidjeti 3. KORAK).
English: Ask your doctor or pharmacist if you are not sure.
Croatian: Pitajte svog liječnika ili ljekarnika ako niste sigurni.
English: • Check your blood sugar and then inject your next dose at the usual time.
Croatian: • Provjerite razinu šećera u krvi te injicirajte sljedeću dozu u uobičajeno vrijeme.
English: Also lumps under the skin caused by build-up of a protein called amyloid may occur (cutaneous amyloidosis, how often they occur is not known).
Croatian: Također se mogu pojaviti kvržice ispod kože uzrokovane nakupljanjem proteina zvanog amiloid (kožna amiloidoza, koliko često se javlja nije poznato).
English: Clinical study safety data are not available for children under 6 years.
Croatian: Sigurnosni podaci iz kliničkih ispitivanja nisu dostupni za djecu mlađu od 6 godina.
English: ANNEX II A. MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION D. CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE USE OF THE MEDICINAL PRODUCT
Croatian: PRILOG II. A. PROIZVOĐAČ BIOLOŠKE DJELATNE TVARI I PROIZVOĐAČI ODGOVORNI ZA PUŠTANJE SERIJE LIJEKA U PROMET B. UVJETI ILI OGRANIČENJA VEZANI UZ OPSKRBU I PRIMJENU C. OSTALI UVJETI I ZAHTJEVI ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET D. UVJETI ILI OGRANIČENJA VEZANI UZ SIGURNU I UČINKOVITU PRIMJENU LIJEKA
English: Your insulin dose may need to be changed during pregnancy and after giving birth.
Croatian: Dozu inzulina možda će trebati promijeniti tijekom trudnoće i nakon poroda.
English: • Skin changes at the injection site:
Croatian: Kožne promjene na mjestu injiciranja:
English: Tell your relatives, friends and close colleagues to get medical help straight away if you are not able to swallow or if you pass out (become unconscious).
Croatian: Recite rodbini, prijateljima i bliskim suradnicima da odmah potraže liječničku pomoć ako ne možete gutati ili ako se onesvijestite.
English: As a consequence, exposure (AUC) in pediatric patients is slightly lower as compared to adult patients when receiving the same body weight adjusted dose.
Croatian: Kao posljedica, izloženost (AUC) u pedijatrijskih bolesnika je malo niža u usporedbi s odraslim bolesnicima kod primjene jednake doze prilagođene prema tjelesnoj težini.