FrancophonIA/ELRC3.0 huggingface dataset:
English: The vaccine virus may spread from vaccinated to non-vaccinated chickens and appropriate care should be taken to separate vaccinated from non-vaccinated.
Danish: Vaccinevirus kan evt. spredes fra vaccinerede til ikke-vaccinerede kyllinger, og der skal drages fornøden omsorg for at skille vaccinerede fra ikke-vaccinerede.
English: Drinking water
Danish: Drikkevand
English: IMMUNOLOGICAL PROPERTIES
Danish: IMMUNOLOGISKE EGNENSKABER
English: Only skimmed milk should be used, since fat in whole milk may block the automatic drinking systems as well as reduce vaccine virus efficacy.
Danish: Der bør kun anvendes skummetmælk, da fedtet i sødmælk kan tilstoppe det automatiske drikkevandssystem samt reducere vaccinens virkning.
English: Since the stability of IBV in suspension may be low due to sensitivity to high temperatures and impurities, water used for dissolving the freeze-dried vaccine should be cool and of good quality.
Danish: Da stabiliteten af IBV i suspension kan være begrænset grundet følsomhed over for høje temperaturer og urenheder, bør der kun anvendes koldt, rent vand til opløsning af den frysetørrede vaccine.
English: The vaccine suspension should be spread evenly over the correct number of chickens, at a distance of 30-40 cm using a coarse spray, preferably when the chickens are sitting together in dim light.
Danish: Vaccinesuspensionen bør fordeles jævnt over det korrekte antal kyllinger med en afstand på 30-40 cm ved anvendelse af en grov forstøvning, helst når kyllingerne sidder tæt sammen i svag belysning.
English: This will vary according to the age of the chickens being vaccinated and the management system, but 250 to 400 ml of water per 1,000 doses is suggested.
Danish: Mængden af vand vil variere afhængigt af kyllingernes alder på vaccinationstidspunktet og af driftsystemet, men der foreslås 250 til 400 ml vand pr. 1.000 doser.
English: One drop should be applied onto one nostril or one eye.
Danish: Applicer en dråbe i et næsebor eller et øje.
English: For administration of the vaccine, as a general rule, dissolve 1,000 doses in one litre per age in days up to a maximum volume of 20 litres per 1,000 doses.
Danish: Ved administration af vaccinen opløses som hovedregel 1.000 doser i 1 liter vand pr. alder i dage op til en maksimal volumen på 20 liter pr. 1.000 doser.
English: Vaccination with Nobilis IB 4-91 may very commonly induce mild respiratory signs of disease which may persist for a few days depending on the health and condition of the chickens.
Danish: Vaccination med Nobilis IB 4-91 kan meget ofte inducere milde, respiratoriske symptomer på sygdom, som kan vare i et par dage, afhængigt af kyllingernes helbred og tilstand.
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals In case of spray administration, personal protective equipment consisting of masks with eye protection should be worn when handling the veterinary medicinal product.
Danish: Særlige forsigtighedsregler for personer, som indgiver lægemidlet til dyr Ved administration af dette veterinærlægemiddel via spray bør der anvendes personligt beskyttelsesudstyr i form af maske med øjenbeskyttelse.
English: Do not mix with any other veterinary medicinal product, except Nobilis IB Ma5 recommended for use with the veterinary medicinal product.
Danish: Må ikke blandes med andre lægemidler til dyr, undtagen Nobilis IB Ma5, der anbefales til brug sammen med produktet.
English: Care should be taken to avoid spread of the vaccine virus from vaccinated chickens to pheasants.
Danish: Der skal drages omsorg for at undgå at sprede vaccinevirus fra vaccinerede kyllinger til fasaner.
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients
Danish: FARMACEUTISKE OPLYSINGER 6.1 Fortegnelse over hjælpestoffer
English: The spray apparatus should be free from sediments, corrosion and traces of disinfectants and ideally should be used for vaccination purposes only.
Danish: Sprøjteudstyret bør være fri for aflejringer, korrosion og rester af desinfektionsmidler og skal helst udelukkende anvendes til vaccination.
English: Turn on mains water when all the vaccine water has been consumed.
Danish: Tænd for vandforsyningen, når alt vaccinevandet er blevet drukket.
English: Pharmacotherapeutic group: Immunologicals for Aves, domestic fowl, live viral vaccine, avian infectious bronchitis virus.
Danish: Farmakoterapeutisk gruppe: Immunologisk veterinærlægemiddel til hønsefugle, tamhøns, levende viral vaccine, aviær infektiøs bronkitis virus.
English: The volume of water for reconstitution should be sufficient to ensure an even distribution when sprayed onto the chickens.
Danish: Mængden af vand, der er anvendt til fortynding, bør være tilstrækkelig til at sikre en jævn fordeling, når den sprayes på kyllingerne.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE CARTON BOX with 1 vial, 10 vials or 10 cups of lyophilisate
Danish: OPLYSNINGER, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE PAPÆSKE med 1 hætteglas, 10 hætteglas eller 10 bægre lyofilisat
English: At least 3.6 log10 EID50 (1 dose) per animal by coarse spray, drinking water or intranasal/ocular administration.
Danish: Mindst 3,6 log10 EID50 (1 dosis) pr. dyr via grov spray, drikkevand eller intranasal/okulær administration.
English: Water should be withheld before vaccination to make the chickens thirsty.
Danish: Vandforsyningen bør afbrydes før vaccination for at gøre kyllingerne tørstige.
English: By adding approximately 2 grams of skimmed milk powder or 20 ml of liquid skimmed milk per litre of water the virus retains its activity longer.
Danish: Ved at tilsætte ca. 2 g skummetmælkspulver eller 20 ml skummetmælk pr. liter vand forlænges virusaktiviteten.
English: By adding skimmed milk to the drinking water the vaccine virus retains its activity longer.
Danish: Ved at tilsætte skummetmælk til drikkevandet vil vaccinevirus være aktivt længere.
English: Sealed aluminium laminate cup with a polypropylene (cup) and polypropylene/polyethylene (lid) contact layer containing 1,000; 2,500; 5,000 or 10,000 doses.
Danish: Forseglet aluminiumlamineret bæger med et kontaktlag af polypropylen (bæger) og polypropylen/polyethylen (låg) indeholdende 1.000; 5.000 eller 10.000 doser.
English: Shelf life of the veterinary medicinal product in aluminium laminate cups as packaged for sale: 24 months.
Danish: Opbevaringstid for veterinærlægemidlet i aluminiumlamineret bæger i salgspakning: 24 måneder.
English: The instructions on reconstitution of both lyophilisates and the subsequent application are to be followed as outlined above for spray and intranasal/ocular administration.
Danish: Anvisningerne for rekonstitution af lyofilisat og efterfølgende indgivelsesmåde skal følges som beskrevet ovenfor for spray og intranasal/okulær administration.
English: Guideline
Danish: Retningslinjer
English: Glass vial (type I hydrolytic glass) of 10 ml containing 500; 1,000; 2,500; 5,000 or 10,000 doses closed with a halogenobutyl rubber bung and sealed with a coded aluminium cap.
Danish: Hætteglas af 10 ml (hydrolytisk type I glas) der indeholder 500; 1.000; 2.500; 5.000 eller 10.000 doser, lukket med en gummiprop af halogenbutyl og forseglet med en kodet aluminiumskappe.
English: Shelf life of the veterinary medicinal product in glass vials as packaged for sale: 9 months.
Danish: Opbevaringstid for veterinærlægemidlet i hætteglas i salgspakning: 9 måneder.
English: The vaccine can be administered to 7-day and older chickens by drinking water.
Danish: Kyllinger, der er 7 dage gamle eller ældre, kan vaccineres via drikkevandet.
English: Guideline when the product is used with Nobilis IB Ma5
Danish: Retningslinjer for anvendelse af produktet sammen med Nobilis IB Ma5
English: Dissolve the vaccine in physiological saline solution or sterile distilled water (usually 30 ml per 1,000 doses, 75 ml per 2,500 doses) and administer by means of a standardized dropper.
Danish: Opløs vaccinen i fysiologisk saltvand eller i sterilt destilleret vand (som regel 30 ml pr. 1.000 doser, 75 ml pr. 2.500 doser) og administrer ved anvendelse af en standardiseret pipette.
English: Nobilis IB 4-91 given at day-old can adversely affect the efficacy of turkey rhinotracheitis (TRT) vaccine given within 7 days.
Danish: Vaccination af daggamle kyllinger med Nobilis IB 4-91 kan have negativ indflydelse på effekten af vaccination mod turkey rhinotracheitis (TRT), der er givet inden for 7 dage.
English: 1x 500 doses 1x 1,000 doses 1x 2,500 doses 1x 5,000 doses 1x 10,000 doses 10x 500 doses 10x 1,000 doses 10x 2,500 doses 10x 5,000 doses 10x 10,000 doses
Danish: 1x 500 doser 1x 1.000 doser 1x 2.500 doser 1x 5.000 doser 1x 10.000 doser 10x 500 doser 10x 1.000 doser 10x 2.500 doser 10x 5.000 doser 10x 10.000 doser
English: These should be clean and free from traces of detergents and disinfectants.
Danish: Disse bør være fri for sæberester og desinfektionsmidler.
English: The vaccine may be delivered as a freeze-dried cake in a glass vial or as freeze-dried spheres in cups.
Danish: Vaccinen leveres som frysetørrede pellets i hætteglas eller som frysetørrede kugler i bægre.
English: Safety and efficacy data are available which demonstrate that Nobilis IB 4-91 can be administered to day-old chicks that are vaccinated either by the subcutaneous or in ovo route with Innovax-ND-IBD.
Danish: Der foreligger sikkerheds- og virkningsdata, som viser, at Nobilis IB 4-91 kan gives til daggamle kyllinger, der er vaccineret med Innovax-ND-IBD enten subkutant eller in-ovo.
English: For the mixed products the onset of immunity is 3 weeks and the duration of immunity is 6 weeks for the claimed protection against the Massachusetts strains and the variant strain 4-91 of IBV.
Danish: For blandede produkter indtræder immunitet efter 3 uger, og hvad angår den angivne beskyttelse mod Massachusetts stammerne og IBV stammevarianten 4-91, er varigheden af immunitet 6 uger.
English: EXP Once reconstituted use within 2 hours.
Danish: EXP Skal anvendes indenfor 2 timer efter rekonstitution.
English: EU/2/98/006/001 (1,000 doses, vial) EU/2/98/006/002 (2,500 doses, vial) EU/2/98/006/003 (5,000 doses, vial) EU/2/98/006/004 (10,000 doses, vial) EU/2/98/006/005 (10x 1,000 doses, vials) EU/2/98/006/006 (10x 2,500 doses, vials) EU/2/98/006/007 (10x 5,000 doses, vials) EU/2/98/006/008 (10x 10,000 doses, vials) EU/2/98/006/009 (1x 500 doses, vial)
Danish: EU/2/98/006/001 (1.000 doser, hætteglas) EU/2/98/006/002 (2.500 doser, hætteglas) EU/2/98/006/003 (5.000 doser, hætteglas) EU/2/98/006/004 (10.000 doser, hætteglas) EU/2/98/006/005 (10x 1.000 doser, hætteglas) EU/2/98/006/006 (10x 2.500 doser, hætteglas) EU/2/98/006/007 (10x 5.000 doser, hætteglas) EU/2/98/006/008 (10x 10.000 doser, hætteglas) EU/2/98/006/009 (1x 500 doser, hætteglas) EU/2/98/006/010 (10x 500 doser, hætteglas)
English: 1,000 doses (3-100 spheres) 2,500 doses (3-100 spheres) 5,000 doses (3-100 spheres) 10,000 doses (3-100 spheres)
Danish: 1.000 doser (3 - 100 kugler) 2.500 doser (3 - 100 kugler) 5.000 doser (3 - 100 kugler) 10.000 doser (3 - 100 kugler)
English: A. MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURER RESPONSIBLE FOR BATCH RELEASE
Danish: A. FREMSTILLER AF DET BIOLOGISK AKTIVE STOF OG FREMSTILLER ANSVARLIG FOR BATCHFRIGIVELSE.
English: In case of the latter presentation the cups may contain 3 up to 100 spheres depending on the required dosages and production yields.
Danish: Et bæger kan indeholde fra 3 kugler op til 100 kugler afhængigt af den nødvendige dosis og produktudnyttelse.
English: The vaccine should be given in the early morning as this is the main period of water intake or during the cool period on a hot day.
Danish: Vaccinen skal gives tidligt om morgenen, da fuglene fortrinsvis drikker på dette tidspunkt, eller i en kølig periode på en varm dag.
English: Nobilis IB 4-91 is intended to protect chickens against respiratory signs of disease caused by IBV variant strain 4-91 only and should not be used as a replacement for other IBV vaccines.
Danish: Nobilis IB 4-91 er udelukkende beregnet til beskyttelse af kyllinger mod respiratoriske symptomer på sygdom der er forårsaget af IBV stammevariant 4-91, og bør ikke anvendes som erstatning for andre IBV vacciner.
English: In-use shelf life after mixing: 2 hours.
Danish: Holdbarhed efter blanding: 2 timer.
English: Vials: off-white/cream-coloured pellet.
Danish: Hætteglas: Råhvide/cremefarvede pellets.
English: 6.6 Special precautions for the disposal of unused veterinary medicinal products or waste materials, derived from the use of such products
Danish: 6.6 Eventuelle særlige forholdsregler ved bortskaffelse af ubrugte veterinærlægemidler eller affaldsmaterialer fra brugen af sådanne
English: EU/2/98/006/010 (10x 500 doses, vials) EU/2/98/006/011 (10x 1,000 doses, cups) EU/2/98/006/012 (10x 5,000 doses, cups) EU/2/98/006/013 (10x 10,000 doses, cups EU/2/98/006/014 (10x 2,500 doses, cups)
Danish: EU/2/98/006/011 (10x 1.000 doser, bægre) EU/2/98/006/012 (10x 5.000 doser, bægre) EU/2/98/006/013 (10x 10.000 doser, bægre) EU/2/98/006/014 (10x 2.500 doser, bægre)
English: 500 doses 1,000 doses 2,500 doses 5,000 doses 10,000 doses
Danish: 500 doser 1.000 doser 2.500 doser 5.000 doser 10.000 doser
English: Withdrawal period: zero days.
Danish: Tilbageholdelsestid: 0 døgn.
English: Active immunisation against avian infectious bronchitis virus variant strain IB 4-91 which causes infectious bronchitis in chickens.
Danish: Aktiv immunisering mod aviær infektiøs bronchitis virus stammevariant IB 4-91, som forårsager infektiøs bronkitis hos kyllinger.
English: BATCH NUMBER.
Danish: BATCHNUMMER
English: QUANTITY OF ACTIVE SUBSTANCE(S)
Danish: MÆNGDEN AF AKTIVT STOF (AKTIVE STOFFER)
English: THE WORDS "KEEP OUT OF THE SIGHT AND REACH OF CHILDREN"
Danish: TEKSTEN “OPBEVARES UTILGÆNGELIGT FOR BØRN”
English: Safety and efficacy data are available which demonstrate that this vaccine can be mixed and administered with Nobilis IB Ma5 for spray or intranasal/ocular administration to commercial chicks from one day of age onwards.
Danish: Der foreligger oplysninger om sikkerhed og virkning, der viser, at vaccinen kan blandes og gives sammen med Nobilis IB Ma5 via spray eller intranasal/okulær administration til kyllinger, der er daggamle og ældre.
English: A sufficient number of water containers to provide adequate drinking space is essential.
Danish: Det er vigtigt, at der er vandingstrug nok, således at der er let adgang til at drikke.
English: Active immunisation of chickens to reduce the respiratory signs of infectious bronchitis caused by the variant strain IB 4-91.
Danish: Aktiv immunisering af kyllinger for at reducere de respiratoriske symptomer på infektiøs bronkitis, som forårsages af stammevarianten IB 4-91.
English: Future layers and breeders: The vaccine can be administered to future layers and breeders from day old onwards via intranasal/ocular route or coarse spray.
Danish: Kommende æglæggere og avlsfugle: Vaccinen kan anvendes til kommende æglæggere og avlsfugle fra daggamle og frem via intranasal/okulær administration eller grov spray.
English: Cups: off-white, predominantly sphere shaped.
Danish: Bægre: Råhvide, overvejende kugleformede.
English: Vials: off-white/cream-coloured pellet Cups: off-white, predominantly sphere shaped
Danish: Hætteglas: Råhvide/cremefarvede pellets Bægre: Råhvide, overvejende kugleformede.
English: Spray method
Danish: Spraymetoden:
English: For oculonasal use, spray or drinking water administration.
Danish: Tilokulonasal anvendelse, spray- eller drikkevandsadministration.
English: The appropriate number of vials should be opened under water or the content of the cup(s) should be poured into the water.
Danish: Det nødvendige antal hætteglas bør åbnes under vandoverfladen eller indholdet af det nødvendige antal bægre hældes i vandet.
English: Oculonasal use, spray or drinking water
Danish: Okulonasal anvendelse, spray eller drikkevand
English: Live attenuated infectious bronchitis virus strain 4-91 ≥ 3.6 log10 EID50* per dose *EID50: 50% embryo infective dose
Danish: Levende attenueret Infektiøs Bronchitis Virus stamme 4-91 ≥ 3,6 log10 EID50 *per dosis * EID50 = 50% embryo infective dose
English: Live attenuated avian infectious bronchitis virus (IBV), variant strain 4-91: ≥ 3.6 log10 EID50* * EID50: 50% embryo infective dose - the virus titre required to produce infection in 50% of the embryos inoculated.
Danish: Levende attenueret aviær infektiøs bronchitis virus (IBV), stammevariant 4-91: ≥ 3,6 log10 EID50 * * EID50 - 50% embryo infective dose: Den virustiterværdi, som er nødvendig for at forårsage infektion i 50% af de inokulerede embryoner.
English: Broiler: The vaccine can be administered to 1-day-old chicks and older chickens by coarse spray or by intranasal/ocular administration.
Danish: Kyllinger: Denne vaccine kan bruges til daggamle og ældre kyllinger via grov spray eller intranasal/intraokulær administration.
English: Lyophilisate for oculonasal suspension/use in drinking water.
Danish: Lyofilisat til okulonasal suspension/brug i drikkevand.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS LABEL - Lyophilisate VIALS
Danish: MINDSTEKRAV TIL OPLYSNINGER PÅ SMÅ INDRE PAKNINGER
English: Packaging:
Danish: Pakningsstørrelser:
English: Lyophilisate for oculonasal suspension/use in drinking water
Danish: Lyofilisat til okulonasal suspension/brug i drikkevand
English: Name and address of the manufacturer of the biological active substance Intervet International B.V.
Danish: Navn og adresse på fremstilleren af det biologisk aktive stof
English: Nobilis IB 4-91 has been shown to be safe in layers and breeders during lay.
Danish: Det er vist, at Nobilis IB 4-91 er sikker at anvende til æglæggere og avlsfugle i æglægningsperioden.
English: The vials should be opened under water or the content of the cup(s) should be poured into the water.
Danish: Hætteglassene bør åbnes under vandoverfladen eller indholdet af det nødvendige antal bægre hældes i vandet.
English: Nobilis IB 4-91 lyophilisate for oculonasal suspension/use in drinking water
Danish: Nobilis IB 4-91 lyofilisat til okulonasal suspension/brug i drikkevand
English: Nobilis IB 4-91 lyophilisate for oculonasal suspension/use in drinking water for chickens
Danish: Nobilis IB 4-91 lyofilisat til okulonasal suspension/brug i drikkevand til kyllinger
English: Coarse spray, oculonasal or in drinking water use.
Danish: Grov spray, okulonasal anvendelse eller til brug i drikkevand.
English: Lay: Nobilis IB4-91 has been shown to be safe in layers and breeders during lay.
Danish: Æglæggende fugle: Det er vist, at Nobilis IB 4-91 er sikker at anvende til æglæggere og avlsfugle i æglægningsperioden.
English: Cardboard box with 10 cups of 2,500 doses.
Danish: Papæske med 10 bægre af 2.500 doser.
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER AND OF THE MANUFACTURING AUTHORISATION HOLDER RESPONSIBLE FOR BATCH RELEASE IN THE EEA, IF DIFFERENT
Danish: Indehaver af markedsføringstilladelsen og fremstiller ansvarlig for batchfrigivelse:
English: Cardboard box with 10 cups of 5,000 doses.
Danish: Papæske med 10 bægre af 5.000 doser.
English: Cardboard box with 1 or 10 vials of 2,500 doses.
Danish: Papæske med 1 eller 10 hætteglas af 2.500 doser.
English: Cardboard box with 10 cups of 1,000 doses.
Danish: Papæske med 10 bægre af 1.000 doser.
English: Cardboard box with 10 cups of 10,000 doses.
Danish: Papæske med 10 bægre af 10.000 doser.
English: Cardboard box with 1 or 10 vials of 500 doses.
Danish: Papæske med 1 eller 10 hætteglas af 500 doser.
English: Cardboard box with 1 or 10 vials of 1,000 doses.
Danish: Papæske med 1 eller 10 hætteglas af 1.000 doser.
English: Cardboard box with 1 or 10 vials of 5,000 doses.
Danish: Papæske med 1 eller 10 hætteglas af 5.000 doser.
English: Marketing authorisation holder and manufacturer responsible for batch release: Intervet International B.V.
Danish: Intervet International B.V.
English: Lyophilisate
Danish: INDIKATIONER
English: See package leaflet.
Danish: Læs indlægssedlen.
English: Cardboard box with 1 or 10 vials of 10,000 doses.
Danish: Papæske med 1 eller 10 hætteglas af 10.000 doser.
English: Pancreatic digest of casein Disodium phosphate Water for injections
Danish: Vand til injektionsvæsker.
English: This is expected to help prevent further heart problems.
Danish: Dette forventes at medvirke til at forebygge yderligere hjerteproblemer.
English: The company provided the results of one study involving over 10,000 patients who had had a heart attack.
Danish: Virksomheden fremlagde resultaterne af et studie med over 10.000 patienter, der havde haft et hjerteanfald.
English: In its letter notifying the Agency of the withdrawal of the application, the company stated that it would not be possible for them to reply to the Agency's concerns within the agreed timeframe.
Danish: I sit brev til agenturet om tilbagetrækningen af ansøgningen anførte virksomheden, at det ikke ville være muligt at svare på agenturets betænkeligheder inden for den aftalte tidsramme.
English: The beneficial effects seen were considered modest, particularly in patients who also took statins, and were not considered to outweigh the increased risks of serious infections in patients treated with the medicine.
Danish: De gavnlige virkninger ansås som beskedne, især hos patienter, der også tog statiner, og ansås ikke for at opveje de øgede risici ved alvorlige infektioner hos patienter, der fik dette lægemiddel.
English: IL-1 beta is part of the immune system (the body's natural defences) and is involved in the inflammatory processes associated with heart and blood vessels problems.
Danish: IL-1 beta indgår i immunsystemet (kroppens naturlige forsvar) og medvirker i de betændelsesprocesser, der er forbundet med hjerte- og blodkarproblemer.
English: The main measure of effectiveness was the decrease in the number of serious events such as heart attack, stroke or death.
Danish: Det primære mål for virkningen var faldet i antallet i alvorlige hændelser som f.eks. hjerteanfald, slagtilfælde eller død.
English: It was to be available as a solution for injection under the skin in pre-filled pens and pre-filled syringes.
Danish: Det skulle markedsføres som injektionsvæske i fyldte penne og sprøjter til indgivelse under huden.
English: The company informed the CHMP that, while an extension to the above-mentioned study will stop, other studies investigating canakinumab for the treatment of other conditions will continue as planned.
Danish: Virksomheden oplyste CHMP om, at en forlængelse af det førnævnte studie vil stoppe, men at andre studier til undersøgelse af canakinumab til behandling af andre sygdomme vil fortsætte som planlagt.
English: The CHMP also questioned the appropriateness of the measure chosen by the company to select patients and to monitor the effectiveness of canakinumab Novartis.
Danish: CHMP stillede også spørgsmålstegn ved hensigtsmæssigheden af den foranstaltning, som virksomheden havde valgt til at udvælge patienter og overvåge virkningen af canakinumab Novartis.
English: By attaching to IL-1 beta, canakinumab blocks its activity and reduces inflammation.
Danish: Ved at binde til IL-1 beta blokerer canakinumab dennes aktivitet og reducerer betændelsen.
English: The active substance in canakinumab Novartis, canakinumab, is a monoclonal antibody (a type of protein) which has been designed to recognise and attach to interleukin 1 (IL-1) beta.
Danish: Det aktive stof i canakinumab Novartis, canakinumab, er et monoklonalt antistof (en type protein), der er designet til at genkende og binde sig til interleukin-1 (IL-1) beta.
English: Canakinumab Novartis was expected to be used to prevent serious events such as stroke, heart attack or death in patients who have already had a heart attack.
Danish: Canakinumab Novartis forventedes at blive anvendt til forebyggelse af alvorlige hændelser som f.eks. slagtilfælde, hjerteanfald eller død hos patienter, der tidligere har haft et hjerteanfald.