FrancophonIA/ELRC3.0 huggingface dataset:
English: Placebocontrolled clinical trials included approximately 1,800 patients of Hoehn and Yahr stages I - V treated with pramipexole.
Croatian: Placebom kontrolirana klinička ispitivanja uključila su oko 1800 bolesnika sa stadijem I-V po Hoehn i Yahru liječenih pramipeksolom.
English: In clinical studies and post-marketing experience cardiac failure has been reported in patients with pramipexole.
Croatian: U kliničkim studijama i tijekom razdoblja nakon izdavanja odobrenja za stavljanje lijeka u promet prijavljeno je zatajenje srca u bolesnika na pramipeksolu.
English: The once daily administration of pramipexole prolonged-release tablets causes less frequent fluctuations in the pramipexole plasma concentration over 24 hours compared to the three times daily administration of pramipexole immediate release tablets.
Croatian: Jednokratna dnevna primjena pramipeksol tableta s produljenim oslobađanjem rjeđe izaziva fluktuacije u koncentracijama pramipeksola u plazmi tijekom 24 sata u usporedbi s trokratnom dnevnom primjenom pramipeksol tableta s trenutnim oslobađanjem.
English: Dose adjustment in patients with hepatic failure is not required, as approx. 90% of absorbed active substance is excreted through the kidneys.
Croatian: Podešavanje doze u bolesnika sa zatajenjem jetre nije potrebno, s obzirom da se oko 90% apsorbirane djelatne tvari izlučuje putem bubrega.
English: The dose will be increased every 5-7 days as directed by your doctor until your symptoms are controlled (maintenance dose).
Croatian: Doza se povisuje svakih 5-7 dana prema uputi liječnika, dok se Vaši simptomi ne stave pod kontrolu (doza održavanja).
English: During dose escalation in pivotal studies, efficacy was observed starting at a daily dose of 1.05 mg of base (1.5 mg of salt).
Croatian: Pri povećavanju doze, u pivotalnim studijama, djelotvornost je primijećena počevši od dnevne doze od 1,05 mg baze (1,5 mg soli).
English: In patients with a creatinine clearance less than 20 ml/min, the daily dose of Oprymea should be administered in a single dose, starting at 0.088 mg of base (0.125 mg of salt) daily.
Croatian: U bolesnika s klirensom kreatinina manjim od 20 ml/min, lijek Oprymea je potrebno primijeniti u jednokratnoj dozi, počevši s 0,088 mg baze (0,125 mg soli) dnevno.
English: The symptoms include: - akinesia (loss of muscle movement) - rigid muscles - fever - unstable blood pressure - tachycardia (increased heart rate) - confusion - depressed level of consciousness (e.g. coma).
Croatian: Simptomi uključuju sljedeće: akinezija (gubitak pokretnosti mišića) ukočenost mišića vrućica nestabilni krvni tlak tahikardija (ubrzan rad srca) smetenost smanjena razina svijesti (npr. koma).
English: Most hallucinations are visual - Dyskinesia (e.g. abnormal, uncontrolled movements of the limbs).
Croatian: Diskinezija (npr. abnormalni, nekontrolirani pokreti udova).
English: Based on the analysis of pooled placebo-controlled trials, comprising a total of 1,923 patients on pramipexole and 1,354 patients on placebo, adverse drug reactions were frequently reported for both groups.
Croatian: Na temelju analize zbirnih podataka iz placebom kontroliranih ispitivanja, koja su obuhvatila 1923 bolesnika na pramipeksolu i 1354 bolesnika na placebu, nuspojave su se često prijavljivale za obje skupine.
English: After that, your doctor may increase the dosing frequency to one 0.26 mg prolonged-release tablet every day.
Croatian: Nakon toga, liječnik će povisiti učestalost doziranja na jednu 0,26 mg tabletu s produljenim oslobađanjem svaki dan.
English: Very rare may affect up to 1 in 10,000 people
Croatian: Vrlo rijetko mogu se javiti u do 1 na 10 000 osoba
English: Symptoms include apathy, anxiety, depression, fatigue, sweating and pain (see section
Croatian: Simptomi uključuju apatiju, anksioznost, depresiju, umor, znojenje i bol (vidjeti dio 4.4).
English: There is no established antidote for overdose of a dopamine agonist.
Croatian: Nije poznat specifični antidot za predoziranje s agonistom dopamina.
English: Table 1: Parkinson's disease Body System Very common
Croatian: Tablica 1: Parkinsonova bolest
English: Oprymea is indicated in adults for treatment of the signs and symptoms of idiopathic Parkinson's disease, alone (without levodopa) or in combination with levodopa, i.e. over the course of the disease, through to late stages when the effect of levodopa wears off or becomes inconsistent and fluctuations of the therapeutic effect occur (end of dose or “on off” fluctuations).
Croatian: Oprymea je indicirana za liječenje znakova i simptoma idiopatske Parkinsonove bolesti u odraslih, u obliku monoterapije (bez levodope) ili u kombinaciji s levodopom, tj. tijekom trajanja bolesti, pa sve do uznapredovale faze, kada učinak levodope jenjava ili postane nestalan te dolazi do fluktuacija u terapijskom učinku (učinak "kraja doze” ili “on-off” fluktuacije).
English: In clinical trials approximately 5% of patients were treated at doses below 1.05 mg of base (1.5 mg of salt).
Croatian: U kliničkim ispitivanjima je oko 5% bolesnika liječeno dozama nižim od 1,05 mg baze (1,5 mg soli).
English: A maximum daily dose of 1.1 mg pramipexole base (1.5 mg of salt) should not be exceeded.
Croatian: Ne smije se prekoračiti maksimalna dnevna doza od 1,1 mg baze pramipeksola (1,5 mg soli).
English: In clinical trials approximately 5% of patients were treated at doses below 1.1 mg of base (1.5 mg of salt).
Croatian: U kliničkim ispitivanjima je oko 5% bolesnika liječeno dozama nižim od 1,1 mg baze (1,5 mg soli).
English: Patients must be informed of this and advised to exercise caution while driving or operating machines during treatment with Oprymea.
Croatian: Tijekom liječenja lijekom Oprymea bolesnici moraju biti informirani o tome, te ih se mora upozoriti na povećan oprez pri upravljanju motornim vozilima ili strojevima.
English: If you have to stop taking this medicine, your doctor will reduce the dose gradually.
Croatian: Ako morate prekinuti uzimanje lijeka, liječnik će Vam postupno snižavati dozu, čime se smanjuje rizik od pogoršanja simptoma.
English: 10 prolonged-release tablets 30 prolonged-release tablets 90 prolonged-release tablets 100 prolonged-release tablets
Croatian: 10 tableta s produljenim oslobađanjem 30 tableta s produljenim oslobađanjem 90 tableta s produljenim oslobađanjem 100 tableta s produljenim oslobađanjem
English: The use of pramipexole has not been studied in haemodialysis patients, or in patients with severe renal impairment.
Croatian: Primjena pramipeksola nije ispitivana u bolesnika na hemodijalizi ili bolesnika s teškim bubrežnim oštećenjem.
English: Common: - Changes in sleep pattern, such as sleeplessness (insomnia) and sleepiness - Tiredness (fatigue) - Headache - Abnormal dreams - Constipation - Dizziness - Vomiting (being sick)
Croatian: Često: promjene u obrascu spavanja, kao što su nesanica (insomnija) i pospanost umor (zamor) glavobolja neobični snovi zatvor omaglica povraćanje
English: In these cases Oprymea may affect your ability to drive and operate machinery.
Croatian: U spomenutim slučajevima, Oprymea može utjecati na sposobnost upravljanja vozilima i rada sa strojevima.
English: 3-week treatment initiation pack contains 21 prolonged-release tablets in 3 packages: - the package marked "Week 1" contains 1 blister of 7 tablets of 0.26 mg, - the package marked "Week 2" contains 1 blister of 7 tablets of 0.52 mg, - the package marked "Week 3" contains 1 blister of 7 tablets of 1.05 mg.
Croatian: Pakiranje za 3-tjedno početno liječenje sadrži 21 tabletu s produljenim oslobađanjem u 3 pakiranja: pakiranje s oznakom „1. tjedan" sadrži 1 blister sa 7 tableta od 0,26 mg.
English: Do not try to make up for the missed dose.
Croatian: Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: How to take Oprymea
Croatian: Kako uzimati lijek Oprymea
English: If you accidentally take too many tablets, - Contact your doctor or nearest hospital casualty department immediately for advice.
Croatian: Trenutno se javite liječniku ili na odjel najbliže bolnice za savjet.
English: Cardiac disorders cardiac failure
Croatian: Srčani poremećaji zatajenje srca
English: If you are switching from Oprymea (immediate release) tablets Your doctor will base your dose of Oprymea prolonged-release tablets on the dose of Oprymea (immediate release) tablets you were taking.
Croatian: Liječnik će započeti s dozom Oprymea tableta s produljenim oslobađanjem adekvatno Vašoj dozi Oprymea tableta (s trenutnim oslobađanjem) koju ste uzimali.
English: Parkinson's disease The daily dose is to be taken divided into 3 equal doses.
Croatian: Dnevna doza se uzima podijeljena u 3 jednake doze.
English: Very common: - Dyskinesia (e.g. abnormal, uncontrolled movements of the limbs) - Sleepiness - Dizziness - Nausea (sickness)
Croatian: Vrlo često: diskinezija (npr. abnormalni, nekontrolirani pokreti udova) pospanost omaglica mučnina
English: - The other ingredients are hypromellose, maize starch, colloidal anhydrous silica and magnesium stearate.
Croatian: Drugi sastojci su hipromeloza, kukuruzni škrob, bezvodni koloidni silicijev dioksid i magnezijev stearat.
English: If necessary, your doctor may increase your tablet dose up to a maximum of 3.3 mg of pramipexole a day.
Croatian: Ako je potrebno, liječnik će povisiti dozu tableta do maksimalno 3,3 mg pramipeksola dnevno.
English: A maximum daily dose of 1.57 mg pramipexole base (2.25 mg of salt) should not be exceeded.
Croatian: Ne smije se prekoračiti maksimalna dnevna doza od 1,57 mg baze pramipeksola (2,25 mg soli).
English: Week 1
Croatian: 1. tjedan
English: The overall incidence of hallucinations and somnolence was generally higher in the escalation phase with the pramipexole group.
Croatian: Ukupna incidencija halucinacija i somnolencije bila je općenito veća tijekom perioda povećanja doze u skupini bolesnika liječenih pramipeksolom.
English: A precise frequency estimation is not possible as the side effect did not occur in a clinical trial database of 1,395 patients with Restless Legs Syndrome treated with pramipexole.
Croatian: Precizna procjena učestalosti nije moguća, s obzirom na to da se nuspojava nije pojavila u bazi podataka kliničkog ispitivanja u 1395 bolesnika sa sindromom nemirnih nogu liječenih pramipeksolom.
English: INNER BOX (week 1)
Croatian: UNUTARNJA KUTIJA (1. tjedan)
English: For the side effects marked with * a precise frequency estimation is not possible, since these side effects were not observed in clinical studies among 1,395 patients treated with pramipexole.
Croatian: Za nuspojave koje su označene sa * nije moguća precizna ocjena učestalosti s obzirom da ove nuspojave nisu primijećene u kliničkim ispitivanjima na 1395 bolesnika liječenih pramipeksolom.
English: INNER BOX (week 2)
Croatian: UNUTARNJA KUTIJA (2. tjedan)
English: Week 3
Croatian: 3. tjedan
English: INNER BOX (week 3)
Croatian: UNUTARNJA KUTIJA (3. tjedan)
English: A lower maintenance dose of one Oprymea 0.26 mg prolonged-release tablet a day is also possible.
Croatian: Također je moguća niža doza održavanja od jedne Oprymea 0,26 mg tablete s produljenim oslobađanjem dnevno.
English: Reduction of the pramipexole dose should be considered when these medicinal products are administered concomitantly with Oprymea.
Croatian: Potrebno je razmotriti mogućnost sniženja doze pramipeksola u slučaju primjene navedenih lijekova u kombinaciji s lijekom Oprymea.
English: How to store Oprymea
Croatian: Kako čuvati lijek Oprymea
English: Treatment initiation pack
Croatian: Pakiranje za početno liječenje
English: Coadministration of antipsychotic medicinal products with pramipexole should be avoided (see section 4.5).
Croatian: Treba izbjegavati istodobnu primjenu antipsihotičnih lijekova i pramipeksola (vidjeti dio 4.5).
English: Table 2: Restless legs syndrome Body System Very common
Croatian: Tablica 2: Sindrom nemirnih nogu
English: Rare may affect up to 1 in 1,000 people
Croatian: Rijetko mogu se javiti u do 1 na 1000 osoba
English: However, it should be noted that the incidence of somnolence is increased at doses higher than 1.05 mg of base (1.5 mg of salt) per day (see section 4.8).
Croatian: Međutim, potrebno je napomenuti da se incidencija somnolencije povećava pri dozama višim od 1,05 mg baze (1,5 mg soli) dnevno (vidjeti dio 4.8).
English: Posology
Croatian: TEKSTA
English: During dose escalation in pivotal studies, efficacy was observed starting at a daily dose of 1.1 mg of base (1.5 mg of salt).
Croatian: Pri povećanju doze u 3 osnovna ispitivanja, djelotvornost je primijećena kod početne dnevne doze od 1,1 mg baze (1,5 mg soli).
English: A precise frequency estimation is not possible as the side effect did not occur in a clinical trial database of 2,762 patients with Parkinson's Disease treated with pramipexole.
Croatian: Precizna procjena učestalosti nije moguća, s obzirom na to da se nuspojava nije pojavila u bazi podataka kliničkog ispitivanja u 2762 bolesnika s Parkinsonovom bolešću liječenih pramipeksolom.
English: Insomnia hallucinations abnormal dreams confusion behavioural symptoms of impulse control disorders and compulsions compulsive shopping pathological gambling restlessness hypersexuality delusion libido disorder paranoia delirium binge eating hyperphagia mania
Croatian: Psihijatrijski poremećaji nesanica halucinacije abnormalni snovi smetenost bihevioralni simptomi u vidu poremećaja kontrole nagona i kompulzija kompulzivno kupovanje patološko kockanje nemir hiperseksualnost sumanutost poremećaj libida paranoja delirij epizode prejedanja hiperfagija manija
English: Very common may affect more than 1 in 10 people
Croatian: Vrlo često mogu se javiti u više od 1 na 10 osoba
English: This side effect has been observed in post-marketing experience.
Croatian: Ova nuspojava je primijećena u razdoblju nakon stavljanja lijeka u promet.
English: If a further dose increase is necessary, doses should be increased by 0.26 mg pramipexole base at weekly intervals up to a maximum dose of 1.57 mg pramipexole base (2.25 mg of salt) per day.
Croatian: Ako je potrebno daljnje povišenje doze, doze se trebaju povisiti za 0,26 mg pramipeksola u obliku baze u tjednim intervalima do maksimalne doze od 1,57 mg baze pramipeksola (2,25 mg soli) dnevno.
English: Pathological gambling, increased libido, hypersexuality, compulsive spending or buying, binge eating and compulsive eating can occur in patients treated with dopamine agonists including Oprymea (see section 4.4).
Croatian: Patološka želja za kockanjem, pojačan libido, hiperseksualnost, kompulzivno trošenje ili kupovanje, prejedanje i kompulzivno jedenje mogu se pojaviti u bolesnika koji se liječe agonistima dopamina, uključujući lijek Oprymea (vidjeti dio 4.4).
English: For the side effects marked with * a precise frequency estimation is not possible, since these side effects were not observed in clinical studies among 2,762 patients treated with pramipexole.
Croatian: Za nuspojave koje su označene sa * nije moguća precizna ocjena učestalosti s obzirom da ove nuspojave nisu primijećene u kliničkim ispitivanjima na 2762 bolesnika liječenih pramipeksolom.
English: Each prolonged-release tablet contains 0.26 mg, 0.52 mg, 1.05 mg, 1.57 mg, 2.1 mg, 2.62 mg or 3.15 mg pramipexole as 0.375 mg, 0.75 mg, 1.5 mg, 2.25 mg, 3 mg, 3.75 mg or 4.5 mg pramipexole dihydrochloride monohydrate, respectively.
Croatian: Jedna tableta s produljenim oslobađanjem sadrži 0,26 mg, 0,52 mg, 1,05 mg, 1,57 mg, 2,1 mg, 2,62 mg ili 3,15 mg pramipeksola u obliku 0,375 mg, 0,75 mg, 1,5 mg, 2,25 mg, 3 mg, 3,75 mg odnosno 4,5 mg pramipeksoldiklorid hidrata.
English: - You may experience vomiting, restlessness, or any of the side effects as described in section 4.
Croatian: Mogu se javiti povraćanje, nemir ili neka od nuspojava koja je opisana u dijelu 4. „Moguće nuspojave“.
English: 7 prolonged-release tablets Week 1
Croatian: 7 tableta s produljenim oslobađanjem 1. tjedan
English: Take care if you are taking the following medicines: - cimetidine (to treat excess stomach acid and stomach ulcers) - amantadine (which can be used to treat Parkinson's disease) - mexiletine (to treat irregular heartbeats, a condition known as ventricular arrhythmia) - zidovudine (which can be used to treat the acquired immune deficiency syndrome (AIDS), a disease of the human immune system) - cisplatin (to treat various types of cancers) - quinine (which can be used for the prevention of painful night-time leg cramps and for the treatment of a type of malaria known as falciparum malaria (malignant malaria)) - procainamide (to treat irregular heart beat).
Croatian: Budite na oprezu ako uzimate sljedeće lijekove: cimetidin (za liječenje prekomjernog stvaranja želučane kiseline i želučanih ulkusa) amantadin (koji se primjenjuje u liječenju Parkinsonove bolesti) meksiletin (za liječenje nepravilnih otkucaja srca, stanja koje se naziva ventrikularna aritmija) zidovudin (koji se može primjenjivati u liječenju stečenog sindroma imunodeficijencije (AIDS), bolesti imunološkog sustava ljudi) cisplatin (za liječenje raznih vrsta raka) kinin (koji se može primjenjivati u prevenciji bolnih grčeva nogu tijekom noći i za liječenje tipa malarije poznatog kao falciparum malaria (maligna malarija)) prokainamid (za liječenje nepravilnih otkucaja srca).
English: The incidence of somnolence is increased at doses higher than 1.5 mg pramipexole salt per day (see section 4.2).
Croatian: Incidencija somnolencije povećava se pri dozama višim od 1,5 mg soli pramipeksola na dan (vidjeti dio 4.2).
English: 1 tablet Oprymea 0.35 mg OR
Croatian: 1 tableta Oprymea 0,35 mg ILI
English: Common: - Urge to behave in an unusual way - Hallucinations (seeing, hearing or feeling things that are not there) - Confusion - Tiredness (fatigue) - Sleeplessness (insomnia) - Excess of fluid, usually in the legs (peripheral oedema) - Headache - Hypotension (low blood pressure) - Abnormal dreams - Constipation - Visual impairment - Vomiting (being sick) - Weight loss including decreased appetite
Croatian: Često: potreba za neoobičajenim ponašanjem halucinacije (vidjeti, čuti ili osjećati stvari koje nisu prisutne) smetenost umor nesanica (insomnija) prekomjerna količina tekućine, obično u nogama (periferni edem) glavobolja hipotenzija (niski krvni tlak) neuobičajeni snovi zatvor poremećaji vida povraćanje gubitak težine uključujući smanjen apetit
English: 7 tablets of Oprymea 1.05 mg
Croatian: 7 Oprymea 1,05 mg tableta
English: 7 prolonged-release tablets Week 2
Croatian: 7 tableta s produljenim oslobađanjem 2. tjedan
English: Each tablet contains 0.088 mg, 0.18 mg, 0.35 mg, 0.7 mg or 1.1 mg pramipexole as 0.125 mg, 0.25 mg, 0.5 mg, 1 mg or 1.5 mg pramipexole dihydrochloride monohydrate, respectively.
Croatian: Jedna tableta sadrži 0,088 mg, 0,18 mg, 0,35 mg, 0,7 mg ili 1,1 mg pramipeksola u obliku 0,125 mg, 0,25 mg, 0,5 mg, 1 mg odnosno 1,5 mg pramipeksoldiklorid hidrata.
English: If necessary, your doctor may increase your dose up to a maximum of 3.15 mg of pramipexole a day.
Croatian: Ako je potrebno, liječnik će povisiti dozu tableta do makisimalno 3,15 mg pramipeksola dnevno.
English: - Sleepiness and episodes of suddenly falling asleep - Psychosis (e.g. comparable with symptoms of schizophrenia) - Vision impairment.
Croatian: Psihoza (npr. usporedivo sa simptomima shizofrenije) Oštećenje vida.
English: - 7 prolonged-release tablets of 1.05 mg
Croatian: 7 tableta s produljenim oslobađanjem od 1,05 mg
English: 7 prolonged-release tablets Week 3
Croatian: 7 tableta s produljenim oslobađanjem 3. tjedan
English: Ascending dose schedule of Oprymea prolonged-release tablets Week Daily dose (mg of base)
Croatian: Raspored doziranja lijeka Oprymea Titracijski korak Večernja doza jedanput dnevno (mg baze)
English: Oprymea 0.088 mg tablets Oprymea 0.18 mg tablets Oprymea 0.35 mg tablets Oprymea 0.7 mg tablets Oprymea 1.1 mg tablets
Croatian: Oprymea 0,088 mg tablete Oprymea 0,18 mg tablete Oprymea 0,35 mg tablete Oprymea 0,7 mg tablete Oprymea 1,1 mg tablete
English: 1 tablet Oprymea 0.35 mg three times a day OR
Croatian: 1 tableta Oprymea 0,35 mg tri puta dnevno ILI
English: Prolonged-release tablet
Croatian: Tableta s produljenim oslobađanjem
English: Oprymea 1.1 mg tablets are white, round, with bevelled edges, both sides scored.
Croatian: Oprymea 1,1 mg tablete su bijele, okrugle, ukošenih rubova i s razdjelnom crtom na obje strane.
English: Thereafter the dose should be reduced by 0.26 mg of base (0.375 mg of salt) per day (see section 4.4).
Croatian: Nakon toga se doza smanjuje za 0,26 mg baze (0,375 mg soli) dnevno (vidjeti dio 4.4).
English: One Oprymea 1.05 mg prolonged-release tablet, OR two Oprymea 0.52 mg prolonged-release tablets, OR four Oprymea 0.26 mg prolonged-release tablets.
Croatian: Jedna Oprymea 1,05 mg tableta s produljenim oslobađanjem ILI dvije Oprymea 0,52 mg tablete s produljenim oslobađanjem ILI četiri Oprymea 0,26 tablete s produljenim oslobađanjem.
English: EXPIRY DATE
Croatian: DATUMREVIZIJE
English: One Oprymea 1.05 mg prolonged-release tablet on blister "Week 3".
Croatian: Jedna Oprymea 1,05 mg tableta s produljenim oslobađanjem iz blistera "3. tjedan".
English: Thereafter the dose should be reduced by 0.264 mg of base (0.375 mg of salt) per day (see section 4.4).
Croatian: Nakon toga se doza smanjuje za 0,264 mg baze (0,375 mg soli) dnevno (vidjeti dio 4.4).
English: Oprymea 0.088 mg tablets Oprymea 0.18 mg tablets Oprymea 0.35 mg tablets Oprymea 0.7 mg tablets Oprymea 1.1 mg tablets Pramipexole
Croatian: Oprymea 0,088 mg tablete Oprymea 0,18 mg tablete Oprymea 0,35 mg tablete Oprymea 0,7 mg tablete Oprymea 1,1 mg tablete pramipeksol
English: In human volunteers, a dose-dependent decrease in prolactin was observed.
Croatian: U zdravih dobrovoljaca primijećeno je, o dozi ovisno, smanjenje razine prolaktina.
English: Gastrointestinal disorders nausea constipation vomiting
Croatian: Poremećaji probavnog sustava mučnina konstipacij povraćanje
English: One Oprymea 0.26 mg prolonged-release tablet on blister "Week 1".
Croatian: Jedna Oprymea 0,26 mg tableta s produljenim oslobađanjem iz blistera "1. tjedan".
English: This is to avoid postural hypotension (a fall in blood pressure on standing up).
Croatian: Potrebno je redovito kontrolirati krvni tlak, osobito na početku liječenja u svrhu izbjegavanja posturalne hipotenzije (pad krvnog tlaka prilikom ustajanja).
English: Uncommon: - Paranoia (e.g. excessive fear for one's own well-being) - Delusion - Excessive daytime sleepiness and suddenly falling asleep - Amnesia (memory disturbance) - Hyperkinesia (increased movements and inability to keep still) - Weight increase - Allergic reactions (e.g. rash, itching, hypersensitivity) - Fainting - Cardiac failure (heart problems which can cause shortness of breath or ankle swelling)* - Inappropriate antidiuretic hormone secretion* - Restlessness - Dyspnoea (difficulties to breathe) - Hiccups - Pneumonia (infection of the lungs) - Inability to resist the impulse, drive or temptation to perform an action that could be harmful to you or others, which may include:
Croatian: Manje često: paranoja (npr. pretjeran strah za vlastitu dobrobit) zabluda (deluzija) prekomjerna dnevna pospanost i iznenadno usnivanje amnezija (poremećaj pamćenja) hiperkinezija (učestali pokreti i nesposobnost ostajanja u mirnom položaju) porast tjelesne težine alergijske reakcije (npr. osip, svrbež, preosjetljivost) nesvjestica zatajenje srca (problemi sa srcem koji mogu izazvati nedostatak zraka ili otečenost gležnjeva)* neodgovarajuće lučenje antidiuretskog hormona* nemir zaduha (otežano disanje) štucanje upala pluća (infekcija pluća) nemogućnost odupiranja nagonu, porivu ili iskušenju za vršenje radnji koje bi mogle naškoditi Vama ili drugima, što može uključivati:
English: 2 tablets Oprymea 0.18 mg three times a day
Croatian: 2 tablete Oprymea 0,18 mg tri puta dnevno tri puta dnevno
English: - Sleepiness and episodes of suddenly falling asleep - Psychosis (e.g. comparable with symptoms of schizophrenia)
Croatian: Psihoza (npr. usporedivo sa simptomima shizofrenije)