FrancophonIA/ELRC3.0 huggingface dataset:
English: Your doctor will decide how many treatment cycles are required.
Croatian: Vaš liječnik će odlučiti koliko je ciklusa liječenja potrebno.
English: Nelarabine should not be used during pregnancy unless clearly necessary.
Croatian: Nelarabin se ne smije primjenjivati tijekom trudnoće, osim u slučaju kada je to izričito nužno.
English: Aspartate aminotransferase increased
Croatian: Povišenje vrijednosti aspartat aminotransferaze
English: Do not try and become pregnant/father a child until your doctor advises you it is safe to do so.
Croatian: Ne pokušavajte zanijeti/začeti dijete sa svojim partnerom/partnericom dok Vam liječnik ne kaže da to možete učiniti bez štetnih posljedica.
English: Other medicines and Atriance
Croatian: Drugi lijekovi i Atriance
English: Pharmacotherapeutic group: Antineoplastic agents, antimetabolites, purine analogues, ATC code: L01B B 07
Croatian: Farmakoterapijska skupina: Antineoplastici, antimetaboliti, analozi purina, ATK oznaka: L01B B 07
English: Survival at one year was 29 % [95 % CI: 12 %-45 %].
Croatian: Preživljenje nakon godine dana iznosilo je 29% [95%-ni CI: 12%-45%].
English: There was a single additional report of biopsy confirmed progressive multifocal leukoencephalopathy in the adult population.
Croatian: Samo je jedno dodatno izvješće o slučaju biopsijom potvrđene progresivne multifokalne leukoencefalopatije, zabilježene u odrasloj populaciji.
English: Your doctor will check for these symptoms regularly during treatment.
Croatian: Vaš liječnik će redovito tijekom liječenja provjeravati te simptome.
English: Based on the pharmacological action of the compound, undesirable effects on fertility are possible.
Croatian: Na temelju saznanja o farmakološkom djelovanju ovoga spoja, mogući su neželjeni učinci na plodnost.
English: You will have an infusion (a drip) once a day on days 1, 3 and 5 of treatment.
Croatian: Infuziju (drip) ćete primati jednom dnevno 1., 3. i 5. dana liječenja.
English: Time to complete response in both classifications of response ranged from 2.9 to 11.7 weeks.
Croatian: U oba slučaja, vrijeme do postizanja potpunoga odgovora kretalo se u rasponu od 2,9 do 11,7 tjedana.
English: • Lowered blood pressure.
Croatian: • Sniženi krvni tlak.
English: What Atriance is and what it is used for
Croatian: Što je Atriance i za što se koristi
English: Two paediatric patients had fatal neurological events.
Croatian: U dva pedijatrijska bolesnika došlo je do pojave fatalnih neuroloških događaja.
English: The dose of Atriance you are given will be based on:
Croatian: Doza lijeka Atriance kojom ćete biti liječeni temeljit će se na:
English: Rarely, it can lead to even more severe bleeding (haemorrhage).
Croatian: U rijetkim slučajevima može doći i do težeg, obilnijeg krvarenja (hemoragije).
English: You/your child (if he/she is being treated) will have an infusion (a drip) once a day for 5 days.
Croatian: Vi/ Vaše dijete (ukoliko se ono liječi) dobivat ćete/dobivat će infuziju (drip) jednom dnevno kroz 5 dana zaredom.
English: Your doctor should perform blood tests regularly during treatment to check for blood problems that have been associated with the use of Atriance.
Croatian: Vaš liječnik će provoditi krvne pretrage redovito tijekom liječenja kako bi provjerio krvne probleme koji se povezuju s primjenom lijeka Atriance.
English: The majority of side effects reported with Atriance were seen in adults, children and adolescents.
Croatian: Većina nuspojava povezanih s lijekom Atriance uočena je u odraslih bolesnika, djece i adolescenata.
English: Some of the side effects were reported more often in adult patients.
Croatian: Neke od nuspojava češće su uočavane u odraslih bolesnika.
English: Peripheral neurological disorders (sensory and motor)
Croatian: Poremećaji perifernog živčanog sustava (senzorni i motorički)
English: Tell your doctor if any of these apply to you.
Croatian: Obavijestite svog liječnika ako se nešto od navedenog odnosi na Vas.
English: This being an approval under exceptional circumstance and pursuant to Article 14(8) of Regulation (EC) No 726/2004, the MAH shall conduct, within the stated timeframe, the following measures:
Croatian: Budući da je ovo odobrenje za stavljanje lijeka u promet u iznimnim okolnostima, sukladno članku 14. stavku 8. Uredbe (EZ) br. 726/2004, nositelj odobrenja dužan je unutar navedenog vremenskog roka provesti sljedeće mjere:
English: Patients must be cautioned that somnolence can affect performance of skilled tasks, such as driving.
Croatian: Bolesnike se mora upozoriti da somnolencija može negativno utjecati na sposobnost izvođenja radnji koje iziskuju određene vještine, poput upravljanja vozilima.
English: • Unintentional rhythmic shaking of one or more limbs (tremors).
Croatian: • Nevoljno ritmično drhtanje jednoga ili više ekstremiteta (tremori).
English: Carcinogenicity testing of nelarabine has not been performed.
Croatian: Ispitivanje karcinogenosti nelarabina nije provedeno.
English: This includes any herbal products or medicines you have bought without a prescription
Croatian: To uključuje i biljne lijekove kao i one koje ste nabavili bez recepta.
English: Atriance has major influence on the ability to drive and use machines.
Croatian: Atriance značajno utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Men with partners who are pregnant or could become pregnant should use condoms during treatment with nelarabine and for at least three months following cessation of treatment.
Croatian: Muškarci čije su partnerice trudne ili mogu zatrudnjeti moraju koristiti prezervative za vrijeme trajanja liječenja te barem tri mjeseca nakon završetka liječenja nelarabinom.
English: Atriance is not recommended for pregnant women.
Croatian: Primjena lijeka Atriance u trudnica se ne preporučuje.
English: What Atriance is and what it is used for What you need to know before you are given Atriance How Atriance is given
Croatian: Što je Atriance i za što se koristi Što morate znati prije nego počnete primati Atriance
English: Both sexually active men and women should use effective methods of contraception during treatment with nelarabine.
Croatian: Spolno aktivni muškarci i spolno aktivne žene moraju primjenjivati učinkovite metode kontracepcije za vrijeme trajanja liječenja nelarabinom.
English: Adults (1,500 mg/m N=103
Croatian: Odrasli (1500 mg/m N=103
English: Clinical studies of nelarabine did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients.
Croatian: Klinička ispitivanja nelarabina nisu uključila dovoljan broj bolesnika u dobi od 65 i više godina, da bi se moglo utvrditi reagiraju li oni na lijek drugačije od mlađih bolesnika.
English: In an exploratory analysis, increasing age, especially age 65 years and older, appeared to be associated with increased rates of neurological adverse events.
Croatian: Eksploracijska analiza je pokazala da je starija životna dob, posebice ona od 65 i više godina, povezana s povišenim stopama neuroloških nuspojava.
English: • Staff should be trained in how to handle and transfer the medicinal product.
Croatian: • Osoblje bi trebalo biti obučeno kako rukovati i prenositi lijek.
English: Atriance is supplied in packs of 1 vial or 6 vials.
Croatian: Atriance je dostupan u pakiranjima s 1 bočicom ili 6 bočica.
English: Atriance contains nelarabine which belongs to a group of medicines known as antineoplastic agents, used in chemotherapy to kill some types of cancer cells.
Croatian: Atriance sadrži nelarabin koji spada u skupinu lijekova poznatih kao antineoplastici koji se koriste u kemoterapiji za uništavanje nekih vrsta stanica raka.
English: Leukaemia causes an abnormal increase in the number of white blood cells.
Croatian: Leukemija uzrokuje abnormalni porast broja bijelih krvnih stanica.
English: • Swelling of parts of the body due to accumulation of abnormal amounts of fluid (oedema).
Croatian: • Oticanje dijelova tijela uslijed nakupljanja abnormalnih količina tekućine (edem).
English: Your doctor will check for these symptoms regularly during treatment (see also section 4, "Possible side effects").
Croatian: Vaš će liječnik redovito tijekom liječenja provjeravati jeste li razvili ovakve simptome (pogledajte i dio 4, „Moguće nuspojave“).
English: What you need to know before you are given Atriance
Croatian: Što morate znati prije nego počnete primati Atriance
English: Nine of these 31 patients failed to respond to prior induction (refractory patients).
Croatian: Devet njih nije reagiralo na ranije liječenje (rezistentni slučajevi).
English: • if you (or your child, if he/she is being treated) are allergic to nelarabine or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste (odnosno Vaše dijete, ako se ono liječi) alergični/alergično na nelarabin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: A doctor or nurse will give you the dose of Atriance as an infusion (a drip).
Croatian: Liječnik ili medicinska sestra dat će Vam dozu lijeka Atriance u obliku infuzije (drip).
English: Nelarabine and ara-G did not significantly inhibit the activities of the major hepatic cytochrome P450 (CYP) isoenzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, or CYP3A4 in vitro.
Croatian: U in vitro uvjetima nelarabin i ara-G nisu u značajnoj mjeri inhibirali aktivnost glavnih izoenzima jetrenoga citokroma P450 (CYP) - CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 ili CYP3A4.
English: Children (650 mg/m N=84
Croatian: Djeca (650 mg/m N=84
English: This medicinal product has been authorised under “exceptional circumstances”.
Croatian: Ovaj lijek je odobren pod „iznimnim okolnostima“.
English: Nelarabine and ara-G are rapidly eliminated from plasma with a half-life of approximately 30 minutes and 3 hours, respectively.
Croatian: Nelarabin i ara-G se brzo eliminiraju iz plazme, pri čemu poluvijek nelarabina iznosi približno 30 minuta, a ara-G oko 3 sata.
English: The effect of nelarabine on fertility in humans is unknown.
Croatian: Učinak nelarabina na plodnost u ljudi nije poznat.
English: Infections and infestations Infection (including but not limited to; sepsis, bacteraemia, pneumonia, fungal infection)
Croatian: Infekcije i infestacije Infekcija (uključujući, no ne svodeći se samo na: sepsu, bakterijemiju, upalu pluća, gljivičnu infekciju)
English: In this case, its cells are called lymphoblasts.
Croatian: U ovom slučaju te stanice se zovu limfoblasti.
English: Supportive care consistent with good clinical practice should be provided.
Croatian: Potrebno je provesti suportivno liječenje sukladno načelima dobre kliničke prakse.
English: Remember to tell your doctor if you start to take any other medicines while you are on Atriance.
Croatian: Sjetite se obavijestiti svog liječnika ukoliko za vrijeme liječenja lijekom Atriance počnete uzimati neki drugi lijek.
English: There is no known antidote for nelarabine overdose.
Croatian: Nema poznatog antidota za liječenje predoziranja nelarabinom.
English: WARNING: Cytotoxic agent, special handling instructions (see package leaflet).
Croatian: UPOZORENJE: Citotoksični lijek, posebne upute za rukovanje (vidjeti uputu o lijeku).
English: Do not use this medicine after the expiry date which is stated on the carton and vial.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici.
English: • High body temperature (fever); tiredness; feeling weak/loss of strength.
Croatian: • Visoka tjelesna temperatura (vrućica); umor, osjećaj slabosti/gubitka snage.
English: Any liquid waste from the preparation of the nelarabine solution for infusion may be flushed with large amounts of water.
Croatian: Sav tekući otpad od pripreme otopine nelarabina za infuziju se može isprati s velikom količinom vode.
English: Male patients, who may wish to father a child, should ask their doctor for family planning advice or treatment.
Croatian: Oboljeli muškarci koji žele postati očevi, moraju se posavjetovati sa svojim se liječnikom oko metoda planiranja obitelji, odnosno načina liječenja.
English: Nelarabine and ara-G are not substantially bound to human plasma proteins (less than 25 %) in vitro, and binding is independent of nelarabine or ara-G concentrations up to 600 µM.
Croatian: U in vitro uvjetima nelarabin i ara-G se ne vežu značajno na proteine ljudske plazme (manje od 25%), i vezivanje je neovisno o koncentraciji nelarabina i ara-G do 600 µM.
English: • Increases in blood levels of liver enzymes.
Croatian: • Porast razine jetrenih enzima u krvi.
English: What Atriance contains
Croatian: Što Atriance sadrži
English: It is usually dripped into your arm over a period of about 1 hour.
Croatian: Ova infuzija obično se daje u krvnu žilu ruke u trajanju od oko 1 sat.
English: (214 %) in adult and paediatric patients, respectively, on day 1 (n = 65 adults, n = 21 paediatric patients).
Croatian: (214%) (n = 65 odraslih bolesnika, n = 21 pedijatrijski bolesnik).
English: See the leaflet for further information.
Croatian: Vidjeti uputu o lijeku za dodatne informacije.
English: (paediatrics).
Croatian: (pedijatrijski bolesnici).
English: Duration of response (in both classifications of response (n=5) ranged between 15 and 195+ weeks.
Croatian: Trajanje odgovora u oba se slučaja (n=5) kretalo u rasponu od 15 do više od 195 tjedana.
English: Nelarabine and ara-G are partially eliminated by the kidneys.
Croatian: Nelarabin i ara-G se djelomice eliminiraju putem bubrega.
English: Clear glass (Type I) vial with a bromobutyl rubber stopper, and an aluminium seal with a red snap-off cap.
Croatian: Bočica od prozirnoga stakla (tip I), s čepom od bromobutilne gume, i s aluminijskim prstenom s crvenom snap-off kapicom.
English: Nervous system disorders Seizures (including convulsions, grand mal convulsions, status epilepticus)
Croatian: Poremećaji živčanog sustava Napadaji (uključujući i konvulzije, konvulzije grand mal tipa, epileptički status)
English: 6 x 50 ml vials 250 mg/50 ml 1 x 50 ml vial 250 mg/50 ml
Croatian: 6 bočica x 50 ml 250 mg/50 ml 1 bočica x 50 ml 250 mg/50 ml
English: Neoplasms benign and malignant (including cysts and polyps) Tumour lysis syndrome - 7 cases (see sections 4.2 and 4.4)
Croatian: Dobroćudne i zloćudne novotvorine (uključujući ciste i polipe) Sindrom lize tumora - 7 slučajeva (vidjeti dijelove 4.2 i 4.4)
English: For the full list of excipients, see section 6.1.
Croatian: Za cjeloviti popis pomoćnih tvari, vidjeti dio 6.1
English: Nelarabine is for intravenous use only and must not be diluted prior to administration.
Croatian: Nelarabin se smije primjenjivati isključivo intravenski i ne smije razrijediti prije primjene.
English: • Violent, uncontrollable muscular contractions often accompanied by unconsciousness that can be due to an epileptic attack (seizures).
Croatian: • Jako, nekontrolirano grčenje mišića, često popraćeno nesvjesticom, koje može biti uzrokovano epileptičkim napadajem.
English: Patients treated previously or concurrently with intrathecal chemotherapy or previously with craniospinal irradiation are potentially at increased risk for neurological adverse events (see section 4.2 - dose modification) and therefore concomitant intrathecal therapy and/or craniospinal irradiation is not recommended.
Croatian: U bolesnika koji su ranije liječeni ili se istodobno liječe intratekalnom kemoterapijom ili su prethodno liječeni kraniospinalnom radioterapijom, rizik od neuroloških nuspojava može biti povećan (vidjeti dio 4.2 - prilagodba doze), te se stoga istodobno provođenje intratekalne terapije i/ili kraniospinalne radioterapije ne preporučuje.
English: It may harm a baby if conceived before, during or soon after treatment.
Croatian: Ovaj lijek može naškoditi djetetu začetom prije, tijekom ili neposredno nakon završetka liječenja.
English: Four (44 %) of the nine refractory patients experienced a complete response to nelarabine.
Croatian: U 4 (44%) od ovih devet rezistentnih bolesnika primjenom nelarabina postignut je potpuni odgovor.
English: • Shortness of breath, difficult or laboured breathing; cough.
Croatian: • Nedostatak zraka, otežano ili forsirano disanje; kašalj.
English: The monophosphate metabolite is subsequently converted to the active 5'-triphosphate form, ara-GTP.
Croatian: Monofosfatni metabolit potom prelazi u aktivni 5'-trifosfatni oblik, ara-GTP.
English: If you have any questions about your illness, talk to your doctor.
Croatian: Imate li bilo kakvih pitanja u svezi svoje bolesti, porazgovarajte sa svojim liječnikom.
English: • the results of blood tests carried out before treatment Adults and adolescents (aged 16 years and older) The usual dose is 1,500 mg/m of body surface area per day.
Croatian: • rezultatima krvnih pretraga učinjenih prije početka liječenja Odrasle osobe i adolescenti (u dobi od 16 i više godina) Uobičajena dnevna doza lijeka iznosi 1500 mg/m površine tijela.
English: No studies have been conducted in animals to assess the effects of nelarabine on fertility.
Croatian: Na životinjama do sada nisu provođena ispitivanja koja bi omogućila utvrđivanje utjecaja nelarabina na plodnost.
English: If a patient becomes pregnant during treatment with nelarabine, they should be informed of the possible risk to the foetus.
Croatian: Ukoliko bolesnica tijekom liječenja nelarabinom zatrudni, valja je upoznati s mogućim rizicima po plod.
English: • The active substance of Atriance is nelarabine.
Croatian: • Djelatna tvar lijeka Atriance je nelarabin.
English: This medicine contains at least 23 mg sodium per dose.
Croatian: Svaka doza ovoga lijeka sadrži barem 23 mg natrija.
English: Nelarabine and 9-β-Darabinofuranosylguanine (ara-G) are partially renally excreted (see section 5.2).
Croatian: Nelarabin i 9-β-Darabinofuranozilgvanin (ara-G) djelomice se izlučuju putem bubrega (vidjeti dio 5.2).
English: • The release of tumour cell contents (tumour lysis syndrome), which may put extra stress on your body.
Croatian: • Oslobađanje sadržaja tumorskih stanica (sindrom razgradnje ili lize tumora), što može dodatno opteretiti Vaš organizam.
English: Nelarabine is excreted by the kidney to a small extent (5 to 10 % of the administered dose).
Croatian: Nelarabin se putem bubrega izlučuje u manjem opsegu (5 do 10% primijenjene doze).
English: • Unusual bruising or bleeding, caused by a decrease in the number of clotting cells in the blood.
Croatian: • Neuobičajeno stvaranje modrica ili sklonost krvarenju uzrokovana smanjenjem broja krvnih pločica u krvi koje sudjeluju u zgrušavanju.
English: This medicinal product contains 1.725 mg/ml (75 micromols/ml) of sodium.
Croatian: Ovaj lijek sadrži 1,725 mg/ml (75 mikromola/ml) natrija.
English: Your doctor will take appropriate precautions to minimise the risk of this.
Croatian: Vaš će liječnik poduzeti potrebne mjere opreza kako bi se rizik od pojave ovoga sindroma sveo na najmanju moguću mjeru.
English: A total of 6 patients (21 %) [95 % CI: 8 %-41 %] achieved a complete response with or without haematological recovery.
Croatian: U ukupno 6 bolesnika (21%) [95%-ni CI: 8%-41%] postignut je potpuni odgovor s ili bez oporavka krvne slike.
English: • Problems with memory, feeling disoriented; blurred vision; altered or loss of sense of taste (dysgeusia).
Croatian: • Problemi pamćenja, osjećaj dezorijentiranosti; zamućenje vida; promijenjen osjet okusa ili njegov potpuni gubitak (disgeuzija).
English: Insufficient numbers of patients aged 65 years of age and older have been treated with nelarabine to determine whether they respond differently than younger patients (see sections 4.4 and 5.2).
Croatian: Broj osoba u dobi od 65 i više godina koje su do sada liječene nelarabinom, nije dostatan da se utvrdi reagiraju li ovi bolesnici na lijek drugačije od mlađih bolesnika (vidjeti dijelove 4.4 i 5.2).
English: • if you (or your child, if he/she is being treated) have any blood problems (for example anaemia).
Croatian: • ako Vi (odnosno Vaše dijete, ako se ono liječi) imate krvne probleme (primjerice anemiju).
English: Symptoms may be mental (e.g. tiredness) or physical (e.g. convulsions, feelings of numbness or tingling, weakness and paralysis).
Croatian: Simptomi mogu biti mentalni (npr. umor) ili fizički (npr. konvulzije, osjećaj obamrlosti ili trnaca, slabost i paraliza).
English: Ara-G is excreted by the kidney to a greater extent (20 to 30 % of the administered nelarabine dose).
Croatian: Ara-G se putem bubrega izlučuje u većoj mjeri (20 do 30% primijenjene doze).
English: A blood test will be taken to check possible reduction of white blood cells.
Croatian: Napravit će se krvna pretraga kojom će se utvrditi je li broj Vaših bijelih krvnih stanica smanjen.
English: • Personnel handling this medicinal product during handling/transfer should wear protective clothing including mask, goggles and gloves.
Croatian: • Osobe koje rukuju ovim lijekom prilikom rukovanja/prijenosa trebale bi nositi zaštitnu odjeću uključujući masku, zaštitne naočale i rukavice.
English: Concomitant administration may reduce the efficacy of nelarabine and/or change the adverse event profile of either active substance.
Croatian: Istodobna primjena može umanjiti djelotvornost nelarabina i/ili promijeniti vrstu nuspojava vezanih uz primjenu i jedne i druge djelatne tvari.
English: Blood and lymphatic system disorders Febrile neutropenia
Croatian: Poremećaji krvi i limfnog sustava Febrilna neutropenija
English: If pregnancy occurs during treatment with Atriance, you must tell your doctor immediately.
Croatian: Ukoliko za vrijeme liječenja lijekom Atriance do začeća ipak dođe, o tome morate odmah obavijestiti svoga liječnika.
English: Concomitant administration of nelarabine in combination with adenosine deaminase inhibitors such as pentostatin is not recommended.
Croatian: Istodobna primjena nelarabina i inhibitora adenozin deaminaze poput pentostatina,se ne preporučuje.
English: It is usually dripped into your arm over a period of about 2 hours.
Croatian: Ova infuzija obično se daje u krvnu žilu ruke u trajanju od oko 2 sata.
English: This means that due to the rarity of the disease it has not been possible to obtain complete information on this medicinal product.
Croatian: To znači da s obzirom na nisku učestalost bolesti nije bilo moguće doći do potpunih informacija o ovom lijeku.
English: Full recovery from these reactions has not always occurred with cessation of nelarabine.
Croatian: Nakon prestanka liječenja nelarabinom nije uvijek postignut potpuni oporavak od tih nuspojava.
English: Very common: 10(12%)
Croatian: Common: 6 (7%)
English: This pattern of treatment will normally be repeated every three weeks.
Croatian: Liječenje je ponavljano svakih 21 dan.
English: • if you (or your child, if he/she is being treated) have recently been, or plan to be vaccinated with a live vaccine (for example polio, varicella, typhoid).
Croatian: • jeste li Vi (ili Vaše dijete, ako se ono liječi) nedavno cijepljeni, ili se planirate/ga planirate cijepiti živim cjepivom (primjerice protiv poliomijelitisa, vodenih kozica, trbušnoga tifusa).
English: (35 %) in adult patients and 10.8 l/h/m
Croatian: (35%) u odraslih bolesnika, odnosno 10,8 l/h/m
English: Rhabdomyolysis, blood creatine phosphokinase increased (see “Postmarketing data”)
Croatian: Rabdomioliza, povišenje kreatin fosfokinaze u krvi (vidjeti „Podaci prikupljeni nakon stavljanja lijeka u promet“)
English: Excipients: Sodium chloride, water for injections, hydrochloric acid, sodium hydroxide.
Croatian: Pomoćne tvari: natrijev klorid, voda za injekcije, kloridna kiselina, natrijev hidroksid.
English: Instructions for handling and disposal of Atriance
Croatian: Upute za rukovanje i odlaganje lijeka Atriance
English: • Clumsiness and lack of coordination affecting balance, walking, limb or eye movements, or speech.
Croatian: • Nespretnost i nekoordiniranost pokreta, što uključuje poremećaj ravnoteže, hoda, pokreta udova ili očiju, odnosno nerazgovijetnost govora.
English: Breast-feeding should be discontinued during treatment with Atriance.
Croatian: Dojenje je potrebno prekinuti za vrijeme liječenja lijekom Atriance.
English: Family planning should be discussed with patients as appropriate.
Croatian: S bolesnicima valja na primjeren način razgovarati o planiranju obitelji.