FrancophonIA/ELRC3.0 huggingface dataset:
English: Distribution studies have demonstrated that placental and milk transfer of cTN3 PF to the foetal and neonatal circulation is negligible.
Croatian: Ispitivanja distribucije pokazala su da je prolaz cTN3 PF-a kroz placentu i majčino mlijeko u fetalnu i neonatalnu cirkulaciju zanemariv.
English: Clearance following subcutaneous dosing was estimated to be 21.0 ml/h in a rheumatoid arthritis population pharmacokinetic analysis, with an inter-subject variability of 30.8% (CV) and an interoccasion variability of 22.0%.
Croatian: U farmakokinetičkoj analizi populacije s reumatoidnim artritisom klirens nakon subkutane primjene procijenjen je na 21,0 ml/h, uz varijabilnost između ispitanika od 30,8% (CV) te 22% varijabilnosti između ispitivanja.
English: In patients with pre-existing or recent onset of demyelinating disorders, the benefits and risks of TNF-antagonist treatment should be carefully considered before initiation of Cimzia therapy.
Croatian: Prije početka terapije Cimzijom u bolesnika s postojećim ili nedavnim nastankom demijelinizirajućih poremećaja treba pažljivo procijeniti koristi i rizike liječenja TNF-antagonistima.
English: • Let go of the needle cap - this allows ava to check if the medication is usable.
Croatian: • Pustite zatvarač igle kako biste omogućili da uređaj „ava” provjeri može li se uložak upotrijebiti.
English: Caution should be exercised when considering TNF-antagonist therapy for patients with a history of malignancy or when considering continuing treatment in patients who develop malignancy.
Croatian: Potreban je oprez kad se razmatra terapija TNF-antagonistima u bolesnika koji u anamnezi imaju malignu bolest ili kada se razmatra nastavak liječenja u bolesnika u kojih se maligna bolest javila tijekom liječenja.
English: The key results from the study are presented in table 4.
Croatian: Ključni rezultati ispitivanja prikazani su u tablici 4.
English: - Do not remove the needle cap from the medication yet.
Croatian: - Nemojte još skinuti zatvarač igle s uloška.
English: If you do not respond well enough to these medicines, you will be given Cimzia to:
Croatian: Ne odgovorite li dovoljno dobro na te lijekove, liječnik će Vam propisati Cimziju kako bi se:
English: Antibody positivity was associated with lowered drug plasma concentration and in some patients with reduced efficacy.
Croatian: Pozitivnost na antitijela bila je povezana sa sniženom koncentracijom lijeka u plazmi, a kod nekih bolesnika, sa smanjenom djelotvornošću.
English: • Patient Reminder Card
Croatian: • Karticu s podsjetnicima za bolesnika
English: Clinical response at Week 16 and 48 The key results of CIMPASI-1 and CIMPASI-2 studies are presented in Table 11.
Croatian: Klinički odgovor u 16. i 48. tjednu Ključni rezultati ispitivanja CIMPASI-1 i CIMPASI-2 prikazani su u Tablici 11.
English: The frequency was increased both in patients treated with placebo (2.8% vs 0.4% in axSpA and RA populations, respectively) as well as in patients treated with Cimzia (4.7% vs 0.8% in axSpA and RA populations, respectively).
Croatian: Učestalost je bila povećana u bolesnika koji su primali placebo (2,8% naspram 0,4% u populaciji s axSpA odnosno RA) kao i u bolesnika liječenih Cimzijom (4,7% naspram 0,8% u populaciji s axSpA odnosno RA).
English: Among patients remaining in the study, who had both baseline values and week 204 values, inhibition of inflammatory signs in both the sacroiliac joints (n=72) and spine (n=82) was largely maintained through Week 204 in the overall axial spondyloarthritis population as well as in both the AS and the nr-axSpA subpopulations.
Croatian: U bolesnika koji su ostali u istraživanju i za koje su postojale i početne vrijednosti i vrijednosti u 204. tjednu, inhibicija znakova upale kako u sakroilijačnim zglobovima (n=72) tako i u kralježnici (n=82) održala se u velikoj mjeri sve do 204. tjedna u ukupnoj populaciji s aksijalnim spondiloartritisom kao i u subpopulacijama s ankilozantnim spondilitisom i neradiografskim aksijalnim spondiloartritisom.
English: Patients with an inadequate response at Week 16 (PASI 50 non-responders) were eligible to receive Cimzia 400 mg every 2 weeks until Week 48 in an open label manner.
Croatian: Bolesnici s nezadovoljavajućim odgovorom u 16. tjednu (bez odgovora po kriteriju PASI 50) bili su podobni za primanje Cimzije od 400 mg svaka 2 tjedna do 48. tjedna, u otvorenom ispitivanju.
English: No dose-limiting toxicity was observed during clinical trials.
Croatian: Tijekom kliničkih istraživanja nije uočena toksičnost koja bi ograničavala dozu.
English: Do not touch the area again before injecting.
Croatian: Nemojte ponovo dotaknuti područje prije injiciranja.
English: There was no effect of gender on the pharmacokinetics of certolizumab pegol.
Croatian: Nema učinka spola na farmakokinetiku certolizumabpegola.
English: Axial spondyloarthritis without radiographic evidence of AS (also known as non-radiographic axial spondyloarthritis)
Croatian: Aksijalni spondiloartritis bez radiografskih dokaza AS-a (također poznat kao neradiografski aksijalni spondiloartritis)
English: Cimzia was shown to neutralise membrane associated and soluble human TNFα in a dose-dependent manner.
Croatian: Pokazalo se da Cimzia, ovisno o dozi, neutralizira membranski vezan i topljiv oblik ljudskog TNFα.
English: N/A: Not Applicable *Wald p-values for Cimzia 200 mg vs. placebo and Cimzia 400 mg vs. placebo comparisons are estimated from a logistic regression model with factors for treatment
Croatian: N/P: Nije primjenjivo * p-vrijednosti po Waldu za usporedbe Cimzia 200 mg naspram placeba i Cimzia 400 mg naspram placeba procijenjene su koristeći model logističke regresije uz faktore za liječenje.
English: (a) Cimzia all dosing regimen = data from Cimzia 200 mg administered every 2 weeks preceded by a loading dose of 400 mg at Weeks 0, 2 and 4 plus Cimzia 400 mg administered every 4 weeks preceded by a loading dose of 400 mg at Weeks 0, 2 and 4 (b) Results are from the randomized set (c) Wald p-values are quoted for the comparison of treatments using logistic regression with factors for treatment and region.
Croatian: (a) Cimzia svi režimi doziranja = podaci kod 200 mg Cimzije primijenjene svaka 2 tjedna s prethodnom udarnom dozom od 400 mg u 0., 2. i 4. tjednu plus 400 mg Cimzije primijenjene svaka 4 tjedna s prethodnom udarnom dozom od 400 mg u 0., 2. i 4. tjednu (b) Rezultati su iz randomiziranog skupa (c) p-vrijednosti po Waldu navedene su za usporedbu liječenja koristeći logističku regresiju uz faktore za liječenje i regiju.
English: At week 12, significant inhibition of inflammatory signs in both sacroiliac joints and the spine was observed in the Cimzia-treated patients (all dose group), in the overall axial spondyloarthritis population as well as in the sub-populations of ankylosing spondylitis and non-radiographic axial spondyloarthritis.
Croatian: U 12. tjednu, značajna inhibicija znakova upale u sakroilijačnim zglobovima i u kralježnici zabilježeni su i u bolesnika liječenih Cimzijom (skupini svih doza), u ukupnoj populaciji s aksijalnim spondiloartritisom kao i u subpopulaciji s ankilozantnim spondilitisom i neradiografskim aksijalnim spondiloartritisom.
English: In the placebo+MTX group, 49.7% of patients experienced no radiographic progression (change in mTSS ≤0.5) at Week 52 compared to 70.3% in the Cimzia+MTX group (p<0.001).
Croatian: U 49,7% bolesnika koji su primali placebo+MTX nije zabilježena radiografska progresija (promjena u mTSS ≤0,5) u 52. tjednu u usporedbi sa 70,3% bolesnika koji su primali Cimziju+MTX (p<0,001).
English: ACR20 Week 12 Week 24 ACR50 Week 12 Week 24
Croatian: ACR20 12. tjedan 24. tjedan ACR50 12. tjedan 24. tjedan
English: • gastrointestinal obstructions (blockages of the digestive system).
Croatian: • gastrointestinalna opstrukcija (začepljenje probavnog sustava).
English: • arm or leg weakness
Croatian: • slabost u rukama i nogama
English: In the placebo-controlled clinical trials, there were more new cases of serious infection in the Cimzia treatment groups (0.07 per patient-year; all doses), compared with placebo (0.02 per patient-year).
Croatian: U placebom kontroliranim kliničkim istraživanjima bilo je više novih slučajeva ozbiljnih infekcija u skupini liječenoj Cimzijom (0,07 na bolesnik-godinu; sve doze) u usporedbi s placebom (0,02 na bolesnik-godinu).
English: Cimzia 200 mg + MTXPlacebo +MTX Difference*
Croatian: Cimzia 200 mg + MTXPlacebo +MTX razlika*
English: Cimzia is used to treat moderate to severe plaque psoriasis.
Croatian: Cimzia se koristi za liječenje umjerene do teške plak psorijaze.
English: The key results of the CIMPACT trial are presented in Table 12.
Croatian: Ključni rezultati ispitivanja CIMPACT prikazani su u Tablici 12.
English: In the placebo group, 52% of patients experienced no radiographic progression (mTSS ≤ 0.0) at Week 52 compared to 69% in the Cimzia 200 mg treatment group.
Croatian: U skupini na placebu u 52% bolesnika nije zabilježena radiografska progresija (mTSS ≤ 0,0) u 52. tjednu u odnosu na 69% u skupini koja je liječena s 200 mg Cimzije.
English: Patients in the Cimzia+MTX group had a greater reduction from baseline in DAS 28 (ESR) compared with the placebo+MTX group observed as early as Week 2 and continued through Week 52 (p<0.001 at each visit).
Croatian: U bolesnika koji su primali Cimziju+MTX uočeno je veće smanjenje vrijednosti DAS28(ESR) u odnosu na početne vrijednosti u usporedbi sa skupinom koja je primala placebo+MTX već u 2. tjednu i nastavilo se do 52. tjedna (p<0,001 pri svakoj posjeti).
English: The efficacy and safety of Cimzia was assessed in DMARD-naïve adult patients with active RA in a randomized, placebo-controlled, double-blind clinical trial (C-EARLY).
Croatian: Djelotvornost i sigurnost Cimzije se ocjenjivala u odraslih bolesnika s aktivnim RA koji prethodno nisu bili liječeni DMARD-ovima u randomiziranom, placebom kontroliranom, dvostruko slijepom kliničkom ispitivanju (C-EARLY).
English: In a placebo-controlled clinical trial in patients with rheumatoid arthritis, similar antibody response between Cimzia and placebo treatment were observed when the pneumococcal polysaccharide vaccine and influenza vaccine were administered concurrently with Cimzia.
Croatian: U placebom kontroliranom kliničkom istraživanju bolesnika s reumatoidnim artritisom uočen je sličan odgovor protutijela pri liječenju Cimzijom i primanju placeba, kada su istodobno s Cimzijom primijenjeni polisaharidno cjepivo protiv penumokoka i cjepivo protiv gripe.
English: The efficacy and safety of Cimzia were evaluated versus etanercept in the CIMPACT study.
Croatian: U ispitivanju CIMPACT procijenjena je djelotvornost i sigurnost Cimzije u usporedbi s etanerceptom.
English: * Cimzia vs placebo: p< 0.0001.
Croatian: * Cimzia naspram placeba: p< 0,0001.
English: You may cover the injection site with a small adhesive bandage, if necessary.
Croatian: Ako je potrebno, mjesto injiciranja možete prekriti manjim samoljepljivim flasterom.
English: • thyroid disorders (goitre, tiredness, weight loss)
Croatian: • smetnje štitnjače (guša, umor, gubitak tjelesne težine)
English: Cimzia should be used during pregnancy only if clearly needed.
Croatian: Cimzia se smije primjenjivati tijekom trudnoće samo ako je uistinu potrebna.
English: If you do not respond well enough to these medicines, you will be given Cimzia in combination with methotrexate to treat your rheumatoid arthritis.
Croatian: Ne reagirate li dovoljno dobro na te lijekove, liječnik će Vam u svrhu liječenja reumatoidnog artritisa propisati Cimziju u kombinaciji s metotreksatom.
English: Week 12 Week 24 BASDAI 50(c,d)
Croatian: 12. tjedan 24. tjedan BASDAI 50(c,d)
English: Cimzia-treated patients reported significant improvements in health-related quality of life as measured by the psoriatic arthritis QoL (PsAQoL) and the SF-36 Physical and Mental Components and in psoriatic arthritis-related productivity at work and within household, as reported by the Work Productivity Survey compared to placebo.
Croatian: U bolesnika liječenih Cimzijom u usporedbi s placebom zabilježena su značajna poboljšanja u kvaliteti života vezanoj uz zdravlje mjerenoj prema QoL psorijatičnog artritisa (PsAQoL) i prema SF-36 Fizičkim i mentalnim komponentama i u produktivnosti na poslu i u domaćinstvu a vezanoj uz psorijatični artritis, kao što je objavljeno u Anketi radne produktivnosti.
English: A pharmacodynamic model based on the Phase III trial data predicts that around 15% of the patients develop antibodies in 6 months at the recommended dose regimen (200 mg every 2 weeks following a loading dose) without MTX co-treatment.
Croatian: faze istraživanja predviđao je da bi oko 15% bolesnika moglo stvoriti protutijela unutar prvih 6 mjeseci liječenja koje se provodi u skladu s preporučenim doziranjem (200 mg svaka 2 tjedna, nakon početne doze) i bez prateće primjene MTXa.
English: Similar results were achieved in both the ankylosing spondylitis and non-radiographic axial spondyloarthritis subpopulations.
Croatian: Slični rezultati postignuti su u subpopulacijama s ankilozantnim spondilitisom i s neradiografskim aksijalnim spondiloartritisom.
English: • shortness of breath with exertion or upon lying down or swelling of the feet (heart failure)
Croatian: • nedostatak zraka u fizičkom naporu, odnosno u ležećem položaju ili otečena stopala (zatajenje srca)
English: There is an increased background risk for lymphoma and leukaemia in rheumatoid arthritis patients with long-standing, highly active, inflammatory disease, which complicates the risk estimation.
Croatian: U bolesnika s reumatoidnim artritisom, u kojih je upalna bolest dugotrajna i visoko aktivna, postoji povećani rizik za razvoj limfoma i leukemije, što otežava procjenu rizika.
English: Cimzia vs. placebo: *p≤0.01, ** p<0.001
Croatian: Cimzia naspram placeba: *p ≤ 0,01, ** p < 0,001
English: The overall percentage of patients that were antibody positive with a persistent reduction of drug plasma concentration was estimated to be 6.8%.
Croatian: Ukupan postotak bolesnika s pozitivnim nalazom na protutijela i trajnim sniženjem koncentracije lijeka u plazmi procijenjen je na 6,8%.
English: Uncommo cardiomyopathies (including heart failure), ischaemic coronary artery disorders, arrhythmias (including atrial fibrillation), palpitations
Croatian: Učestalost Nuspojave manje često kardiomiopatije (uključujući zatajenje srca), ishemijski poremećaji koronarnih arterija, aritmije (uključujući fibrilaciju atrija), palpitacije
English: Non-responder imputation was used for missing data.
Croatian: Za nedostajuće podatke koristilo se uvrštavanje bolesnici bez odgovora.
English: • Do not re-use the syringe.
Croatian: • Nemojte ponovo koristiti štrcaljku.
English: Evaluation for treatment of signs and symptoms and inhibition of structural damage in DMARD naïve patients.
Croatian: Ocijeniti uspjeh liječenja znakova i simptoma bolesti te inhibicije strukturalnih oštećenja u bolesnika koji prethodno nisu bili liječeni DMARD-ovima.
English: The efficacy and safety of 2 dose regimens (200 mg every 2 weeks and 400 mg every 4 weeks) of Cimzia versus placebo were assessed in an 18-week, open-label, run-in, and 16-week randomised, double-blind, placebo-controlled clinical trial in adult patients with active rheumatoid arthritis diagnosed according to the ACR criteria who had inadequate response to MTX.
Croatian: Djelotvornost i sigurnost 2 režima doziranja (200 mg svaka 2 tjedna i 400 mg svaka 4 tjedna) Cimzije naspram placeba ocjenjivana je u 18-tjednom, otvorenom razdoblju prije početka istraživanja tijekom kojeg se nije primala terapija, i 16-tjednom randomiziranom, dvostruko slijepom, placebom kontroliranom kliničkom istraživanju u odraslih bolesnika s dijagnozom aktivnog reumatoidnog artritisa postavljenoj prema ACR kriterijima koji su imali neprimjeren odgovor na MTX.
English: If your doctor has allowed you to self-inject and you forget to give yourself an injection, you should inject the next dose of Cimzia as soon as you remember.
Croatian: Ako Vam je liječnik odobrio da sami injicirate lijek i Vi ste ga zaboravili injicirati, injicirajte sljedeću dozu čim se sjetite.
English: Sodium acetate Sodium chloride Water for injections
Croatian: 6.1 Popis pomoćnih tvari natrijev acetat natrijev klorid voda za injekcije
English: In the pivotal studies, for subjects who were ANA negative at baseline, 16.7% of those treated with Cimzia developed positive ANA titers, compared with 12.0% of subjects in the placebo group.
Croatian: U ključnim studijama, tijekom liječenja Cimzijom 16,7% ispitanika koji su na početku liječenja bili ANA negativni razvili su pozitivni ANA titar, u usporedbi s 12% ispitanika u placebo skupini.
English: - Only remove the needle cap when you are ready to inject.
Croatian: - Skinite zatvarač igle tek kad budete spremni injicirati lijek.
English: Cimzia-treated patients also had improvements compared to placebo in multiple components of axial spondyloarthritis disease activity, including CRP.
Croatian: Bolesnici koju su liječeni Cimzijom također su imali poboljšanje više komponenti aktivnosti aksijalnog spondiloartritisa u usporedbi s placebom, uključujući CRP.
English: Patients had a Psoriasis Area and Severity Index (PASI) score ≥ 12, body surface area (BSA) involvement of ≥ 10%, Physician Global Assessment (PGA) of ≥ 3, and were candidates for systemic therapy and/or phototherapy and/or chemophototherapy.
Croatian: Physician Global Assessment, PGA) od ≥ 3 i bili su kandidati za sistemsku terapiju i/ili fototerapiju i/ili kemoterapiju.
English: • If you need to have a second injection as prescribed by your doctor repeat the injection process starting at Step 2.
Croatian: • Ako Vam je liječnik propisao da trebate primijeniti još jednu injekciju, ponovite postupak injiciranja od 2. koraka.
English: Physical function response and health-related outcomes In RA-I and RA-II, Cimzia-treated patients reported significant improvements in physical function as assessed by the Health Assessment Questionnaire - Disability Index (HAQ-DI) and in tiredness (fatigue) as reported by the Fatigue Assessment Scale (FAS) from Week 1 through to the end of the studies compared to placebo.
Croatian: U RA-I i RA-II, u skupini bolesnika liječenih Cimzijom zabilježena su značajna poboljšanja fizikalne funkcije ocijenjeno Upitnikom za procjenu zdravlja - indeks nesposobnosti (HAQ-DI) i umora određenog Ljestvicom za procjenu umora (FAS) od 1. tjedna do kraja ispitivanja, u usporedbi s placebom.
English: • signs of infection such as fever, malaise, wounds, dental problems, burning on urination
Croatian: • znakovi infekcije kao što su vrućica, opća slabost, rane, problemi sa zubima, peckanje prilikom mokrenja
English: Of the 135 patients randomised to Cimzia 400 mg every 4 weeks, 89, 62 and 41 patients had an ACR 20/50/70 response, respectively.
Croatian: Od 135 bolesnika randomiziranih na 400 mg Cimzije svaka 4 tjedna, 89, 62 odnosno 41 bolesnik imao je ACR 20/50/70 odgovor.
English: Read the instructions below carefully - this explains how to inject Cimzia by means of a dosedispenser cartridge.
Croatian: Pažljivo pročitajte upute u nastavku jer one objašnjavaju kako injicirati Cimziju uz pomoć uloška za dozator.
English: Cimzia can be used during breastfeeding.
Croatian: Cimzia se može primjenjivati tijekom dojenja.
English: Key efficacy outcomes from the AS001 clinical trial are shown in Table -8.
Croatian: Ključni ishodi djelotvornosti iz AS001 kliničkog istraživanju prikazani su u tablici 8.
English: • Do not re-use the pen.
Croatian: • Nemojte ponovo koristiti brizgalicu.
English: The overall percentage of patients that were antibody positive with a persistent reduction of drug plasma concentration was estimated to be 9.1%.
Croatian: Ukupan postotak bolesnika koji su bili pozitivni na protutijela sa stalnim sniženjem koncentracije lijeka u plazmi procijenjen je na 9,1 %.
English: Patients originally randomized to Cimzia who achieved a PASI75 response at Week 16 were rerandomized based on their original dosing schedule.
Croatian: Bolesnici koji su početno randomizirani za primanje Cimzije i postigli su odgovor PASI 75 u 16. tjednu, ponovno su randomizirani prema početnom rasporedu doze.
English: *These events have been related to this class of medicines but the incidence with Cimzia is not known.
Croatian: *Ti su događaji povezani s ovom skupinom lijekova, ali nepoznata je učestalost pojavljivanja tijekom liječenja Cimzijom.
English: Rare skin exfoliation and desquamation, bullous conditions, hair texture disorder, Stevens-Johnson syndrome**, erythema multiforme**, lichenoid reactions
Croatian: Poremećaji kože i potkožnog tkiva rijetko eksfolijacija i deskvamacija kože, bulozne promjene kože, poremećaji strukture dlaka, Stevens-Johnsonov sindrom**, multiformni eritem**, lihenoidne reakcije
English: Available data in adults with plaque psoriasis suggest that a clinical response is usually achieved within 16 weeks of treatment.
Croatian: Dostupni podaci, u odraslih bolesnika s plak psorijazom ukazuje kako se klinički odgovor obično postiže unutar 16 tjedana od početka liječenja.
English: • Keep the container out of the sight and reach of children.
Croatian: • Čuvajte spremnik izvan pogleda i dohvata djece.
English: Cimzia treatment inhibited the radiographic progression compared with placebo treatment at Week 24 as measured by change from baseline in total mTSS Score (LS mean [±SE] score was 0.28 [±0.07] in the placebo group compared with 0.06 [±0.06] in the Cimzia all doses group; p=0.007).
Croatian: Liječenje Cimzijom inhibiralo je radiografsku progresiju u usporedbi s placebom u 24. tjednu mjereno kao promjena u odnosu na početno stanje u ukupnom mTSS zbroju (LS srednja vrijednost [±SE] bila je 0,28 [±0,07] u placebo skupini u usporedbi s 0,06 [±0,06] u svim skupinama koje su dozirale Cimziju; p=0,007).
English: At baseline, 37 % and 41% of patients had high disease activity (ASDAS ≥2.1, ≤3.5) and 62% and 58% of patient had very high disease activity (ASDAS >3.5) in the CIMZIA group and placebo group respectively.
Croatian: Na početku je 37% i 41% bolesnika imalo visoku aktivnost bolesti (ASDAS ≥2,1, ≤3,5), a 62% i 58%
English: • If something is not clear - please ask your doctor or pharmacist.
Croatian: • Ako Vam nešto nije jasno, obratite se svom liječniku ili ljekarniku.
English: At the end of this period the pre-filled syringes must be used or discarded.
Croatian: Na kraju tog razdoblja napunjene brizgalice moraju se upotrijebiti ili baciti.
English: - The message “You have 1 injection left” will be shown on screen.
Croatian: • Ako Vam je liječnik propisao da trebate primijeniti još jednu injekciju: - Na zaslonu će se prikazati poruka „Ostala vam je još 1 injekcija“.
English: - You can choose “slowest”, “slow”, “fast” or “fastest” - this controls how fast the medicine will be injected and should be selected (and adjusted) as per your personal comfort preference.
Croatian: - Možete odabrati „najsporije”, „sporo”, „brzo” ili „najbrže”.
English: METHOD AND ROUTE(S) OF ADMINISTRATION Subcutaneous use.
Croatian: NAČIN I PUT(EVI) PRIMJENE LIJEKA Supkutana primjena.
English: Treatment success of “clear” (0) or “almost clear”(1) consisted of no signs of psoriasis or normal to pink coloration of lesions, no thickening of the plaque, and none to minimal focal scaling.
Croatian: značila je bez znakova psorijaze ili normalne do ružičaste boje lezija, bez zadebljanja plaka i bez do minimalnog žarišnog ljuštenja.
English: The total content (1 ml) of the pre-filled syringe should be administered as a subcutaneous injection only.
Croatian: Ukupan sadržaj (1 ml) u napunjenoj štrcaljki treba primijeniti samo kao supkutanu injekciju.
English: • After injection, immediately throw away the used syringe(s) in a special container as instructed by your doctor, nurse or pharmacist.
Croatian: • Odmah nakon injiciranja bacite upotrijebljenu(e) brizgalicu(e) u posebni spremnik kao što Vam je to rekao liječnik, medicinska sestra ili ljekarnik.