FrancophonIA/ELRC3.0 huggingface dataset:
English: The Committee for Medicinal products for Human Use (CHMP) decided that Protopy's benefits are greater than its risks for the treatment of moderate to severe atopic dermatitis in adults and children over the age of 2 who are not adequately responsive to or are intolerant of conventional therapies.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) meni, da so koristni učinki zdravila Protopy pri zdravljenju zmernega do hudega atopičnega dermatitisa pri odraslih in otrocih, starih 2 leti ali več, ki se neustrezno odzivajo na običajne terapije ali pa jih ne prenašajo, večji od z njim povezanih tveganj.
English: Afterwards, application should be reduced to once a day until the skin is clear.
Slovenian: Potem je treba pogostnost uporabe zmanjšati na enkrat dnevno in zdravilo uporabljati, dokler spremembe ne izginejo.
English: The full EPAR for Protopy is available here.
Slovenian: Celotno Evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Protopy je na voljo tukaj.
English: The ointment should be applied as a thin layer to affected areas of the skin.
Slovenian: Na prizadete predele kože je treba nanesti tanko plast mazila.
English: What is Protopy used for?
Slovenian: Za kaj se zdravilo Protopy uporablja?
English: The six main clinical studies involved 1,202 adults (over the age of 16) and 1,535 children (aged 2 to 16 years of age), and Protopy was compared either with placebo (a dummy treatment, the ointment base) or with a topical corticosteroid often used for eczema (hydrocortisone butyrate in adults, hydrocortisone acetate in children).
Slovenian: V šestih glavnih kliničnih raziskavah je sodelovalo 1202 odraslih bolnikov (starejših od 16 let) in 1535 otrok (starih od 2 do 16 let).
English: How has Protopy been studied?
Slovenian: Kako je bilo zdravilo Protopy raziskano?
English: What is Protopy?
Slovenian: Kaj je zdravilo Protopy?
English: How does Protopy work?
Slovenian: Kako zdravilo Protopy deluje?
English: For the full list of all the side effects reported with Protopy, please see the Package Leaflet.
Slovenian: Celovit opis neželenih učinkov, o katerih so poročali pri uporabi zdravila Protopy, najdete v Navodilih za uporabo.
English: How is Protopy used?
Slovenian: Kako se zdravilo Protopy uporablja?
English: However, doctors must ensure that the medicine is used appropriately.
Slovenian: Povezava z zdravilom Protopy ni bila dokazana, vendar se morajo zdravniki tega zavedati in zagotoviti, da se zdravilo uporablja pravilno ter da bolnika spremljajo med zdravljenjem.
English: Treatment may continue up to 14 days
Slovenian: 2 Zdravljenje se lahko nadaljuje do 14 dni.
English: Less than 10
Slovenian: Manj kot 10
English: Such reactions may be life-threatening.
Slovenian: Takšne reakcije so lahko smrtno nevarne.
English: Children or adolescents
Slovenian: Otroci ali mladostniki
English: If this happens, do not take medicines that stop or slow bowel movement.
Slovenian: Če se to zgodi, ne jemljite zdravil, ki ustavijo ali upočasnijo gibanje črevesa.
English: Meropenem alone is not known to interact with active transport systems.
Slovenian: Za sam meropenem ni znano nobeno medsebojno delovanje z aktivnimi transportnimi sistemi.
English: Unknown (cannot be estimated from the available data)
Slovenian: Neznana (ni mogoče oceniti iz razpoložljivih podatkov)
English: Your doctor will decide how many days of treatment are needed, depending on the type of infection.
Slovenian: Vaš zdravnik bo določil, koliko dni mora trajati vaše zdravljenje, odvisno od vrste okužbe.
English: 20 to 39
Slovenian: Od 20 do 39
English: This is because it is not known if the medicine is safe to use in these age groups.
Slovenian: Ni namreč znano, ali je uporaba zdravila v tej starostni skupini varna.
English: Small amounts of this medicine may pass into the breast milk and it may affect the baby.
Slovenian: Majhne količine tega zdravila bi lahko prehajale v mleko in vplivale na otroka.
English: New infection
Slovenian: Nova okužba
English: It is particularly important to tell your doctor if you are taking any of the following medicines:
Slovenian: Še zlasti je pomembno, da obvestite zdravnika, če jemljete katero koli od naslednjih zdravil:
English: Because a risk to the newborns/infants cannot be excluded, breastfeeding must be discontinued prior to initiating therapy.
Slovenian: Ker tveganja za dojene novorojence/otroke ne moremo izključiti, je treba pred začetkom zdravljenja prenehati z dojenjem.
English: The reconstituted vial should be further diluted immediately.
Slovenian: Rekonstituirano vialo je treba takoj dodatno razredčiti.
English: This medicine can affect your liver.
Slovenian: To zdravilo lahko vpliva na jetra.
English: • Swelling of the tongue, face, lips or throat
Slovenian: • oteklost jezika, obraza, ustnic ali žrela
English: MARKETING AUTHORISATION NUMBER(S) EU/1/18/1334/001
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/18/1334/001
English: Within each System Organ Class, undesirable effects are presented in order of decreasing seriousness.
Slovenian: V vsakem organskem sistemu so neželeni učinki razvrščeni po padajoči resnosti.
English: Meropenem is mostly eliminated unchanged.
Slovenian: Meropenem se večinoma izloči v nespremenjeni obliki.
English: Minimum inhibitory concentration (MIC) breakpoints established by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) are as follows:
Slovenian: Mejne vrednosti minimalne zaviralne koncentracije (MZK), ki jih je določil Evropski odbor za testiranje protimikrobne občutljivosti (EUCAST), so naslednje:
English: The safety and efficacy of meropenem/vaborbactam in children and adolescents younger than 18 years of age have not yet been established.
Slovenian: Varnost in učinkovitost meropenema/vaborbaktama pri otrocih in mladostnikih, mlajših od 18 let, še nista dokazani.
English: This may affect your ability to drive, use tools or machines.
Slovenian: To lahko vpliva na vašo sposobnost za vožnjo, uporabo orodij in upravljanje strojev.
English: If you have kidney problems, your doctor may lower your dose.
Slovenian: Če imate težave z ledvicami, vam bo zdravnik morda zmanjšal odmerek.
English: • medicines that weaken your body's immune system, such as tacrolimus, everolimus and cyclosporine
Slovenian: • zdravila, ki oslabijo imunski sistem telesa, kot so takrolimus, everolimus in ciklosporin;
English: • Peptostreptococcus species (including P. micros, P anaerobius, P. magnus)
Slovenian: • Peptostreptococcus species (vključno s P. micros, P anaerobius, P. magnus)
English: Your doctor will monitor you closely for any new infections and give you another treatment if necessary.
Slovenian: Vaš zdravnik bo pozoren na morebitne nove okužbe in vam bo po potrebi predpisal drugo zdravilo.
English: 7 to 14 days
Slovenian: 3 ure od 7 do 14 dni
English: About 25% of the administered dose is eliminated as the inactive open ring form.
Slovenian: Približno 25 % uporabljenega odmerka se izloči v neaktivni obliki odprtega obroča.
English: Adverse reactions are classified according to frequency and System Organ Class.
Slovenian: Neželeni učinki so razvrščeni glede na pogostnost in organski sistem.
English: 3 hours
Slovenian: 3 ure
English: If a severe allergic reaction occurs, treatment with Vaborem must be discontinued immediately and adequate emergency measures must be initiated.
Slovenian: Če nastopi huda alergijska reakcija, je treba zdravljenje z zdravilom Vaborem nemudoma prekiniti in uvesti ustrezne nujne ukrepe.
English: It is unknown whether a potential interaction would result in increased or decreased plasma concentrations, and thus patients should be monitored both for signs of toxicity and lack of efficacy of the narrow therapeutic index drug.
Slovenian: Ni znano, ali bi morebitno medsebojno delovanje povzročilo zvišane ali znižane koncentracije v plazmi, zato je treba bolnike spremljati glede znakov toksičnosti in pomanjkanja učinkovitosti zdravila z ozkim terapevtskim indeksom.
English: From a microbiological point of view, the medicinal product should be used immediately upon reconstitution and dilution.
Slovenian: Z mikrobiološkega stališča je treba zdravilo uporabiti takoj po rekonstituciji in razredčitvi.
English: Vaborem should not be used in children or adolescents under 18 years of age.
Slovenian: Zdravila Vaborem ne smejo uporabljati otroci in mladostniki, mlajši od 18 let.
English: 1 As calculated using the Cockcroft-Gault formula
Slovenian: 1 Izračunano po Cockcroft-Gaultovi formuli.
English: • oral anticoagulant medicines, such as warfarin (used to treat or prevent blood clots)
Slovenian: • peroralna antikoagulacijska zdravila, kot je varfarin (uporabljajo se za zdravljenje ali preprečevanje krvnih strdkov);
English: Minimum Inhibitory Concentrations (mg/l) Susceptible
Slovenian: Minimalne zaviralne koncentracije (mg/l) Občutljivi
English: Antibacterial activity in combination with other antibacterial agents
Slovenian: Protibakterijsko delovanje v kombinaciji z drugimi protibakterijskimi učinkovinami
English: The use of meropenem/vaborbactam may result in the overgrowth of non-susceptible organisms, which may require interruption of treatment or other appropriate measures.
Slovenian: Uporaba meropenema/vaborbaktama lahko povzroči razrast neobčutljivih organizmov, zato bodo morda potrebni prekinitev zdravljenja ali drugi ustrezni ukrepi.
English: The number of vials used for a single dose will depend on the creatinine clearance (CrCl) of the patient.
Slovenian: Število vial, ki se uporabijo za posamezen odmerek, je odvisno od bolnikovega očistka kreatinina (CrCl).
English: • you are allergic to other carbapenem antibiotics (the group to which meropenem belongs).
Slovenian: • ste alergični na druge karbapenemske antibiotike (skupina, v katero spada meropenem),
English: Approximately 75 to 95% of vaborbactam is excreted unchanged in the urine over a 24 - 48 hour period.
Slovenian: Približno 75-95 % vaborbaktama se v nespremenjeni obliki izloči z urinom v 24-48 urah.
English: • A positive result from a test called“Coombs”used to identify haemolytic anemia (see above) or reaction of your immune system to Vaborem
Slovenian: • Pozitiven rezultat t. i. »Coombsovega testa«, ki se uporablja za ugotavljanje hemolitične anemije (glejte zgoraj) ali reakcije vašega imunskega sistema na zdravilo Vaborem
English: The risk may vary with the underlying infection, age and general status of the patient so that the contribution of the antibacterial agent to the increase in international normalised ratio (INR) is difficult to assess.
Slovenian: Tveganje se razlikuje glede na okužbo, starost in splošno stanje bolnika, zato je v teh okoliščinah težko oceniti vpliv protibakterijske učinkovine na povečanje mednarodno normaliziranega razmerja (INR).
English: The powder for concentrate for solution for infusion must be reconstituted and further diluted prior to use.
Slovenian: Prašek za koncentrat za raztopino za infundiranje je treba pred uporabo rekonstituirati in razredčiti.
English: Approximately 40-60% of a meropenem dose is excreted unchanged within 24 - 48 hours with a further 25% recovered as the microbiologically inactive hydrolysis product.
Slovenian: Približno 40-60 % odmerka meropenema se izloči v nespremenjeni obliki v 24-48 urah, medtem ko se dodatnih 25 % odmerka izloči kot mikrobiološko neaktiven produkt hidrolize.
English: If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before receiving this medicine.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, preden dobite to zdravilo.
English: The effects of meropenem/vaborbactam on fertility in humans have not been studied.
Slovenian: Učinkov meropenema/vaborbaktama na plodnost pri ljudeh niso preučili.
English: • Haemolytic anaemia (a condition where red blood cells are damaged and reduced in number), which may make you feel tired and turn your skin and eyes yellow
Slovenian: • hemolitična anemija (bolezen, pri kateri so rdeče krvne celice poškodovane, njihovo število pa zmanjšano), zaradi česar se lahko počutite utrujene ter imate porumenelo kožo in oči
English: Medicinal products that inhibit peristalsis should not be given.
Slovenian: Zdravil, ki zavirajo peristaltiko, se ne sme dajati.
English: 10 to 19
Slovenian: Od 10 do 19
English: <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); unknown (cannot be estimated from the available data).
Slovenian: Pogostnost je opredeljena kot: zelo pogosti (≥ 1/10); pogosti (≥ 1/100 do < 1/10); občasni (≥ 1/1.000 do < 1/100); redki (≥1/10.000 do < 1/ 1.000); zelo redki (< 1/10.000); neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: Infections due to aerobic Gram-negative organisms in patients with limited treatment options
Slovenian: Okužbe zaradi aerobnih gramnegativnih organizmov pri bolnikih z omejenimi možnostmi zdravljenja
English: As a precautionary measure, it is preferable to avoid the use of Vaborem during pregnancy.
Slovenian: Iz previdnostnih razlogov se je med nosečnostjo uporabi zdravila Vaborem bolje izogibati.
English: PHARMACEUTICAL FORM AND CONTENTS Powder for concentrate
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA prašek za koncentrat
English: In individuals with normal renal function, rapid renal elimination will occur.
Slovenian: Pri posameznikih z normalnim delovanjem ledvic bo prišlo do hitrega izločanja skozi ledvice.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with Vaborem in one or more subsets of the paediatric population in the treatment of infections due to Gramnegative bacteria (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z zdravilom Vaborem za eno ali več podskupin pediatrične populacije za zdravljenje okužb z gramnegativnimi bakterijami (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Your doctor may also want to do some blood tests to see how well your kidneys are working.
Slovenian: Zdravnik lahko tudi opravi krvne preiskave za ugotavljanje, kako dobro delujejo vaše ledvice.
English: Pharmacotherapeutic group: antibacterials for systemic use, carbapenems, ATC code: J01DH52
Slovenian: Farmakoterapevtska skupina: zdravila za sistemsko zdravljenje bakterijskih infekcij, karbapenemski antibiotiki; oznaka ATC: J01DH52
English: The most common adverse reactions that occurred among 322 patients from the pooled Phase 3 trials were headache (8.1%), diarrhoea (4.7%), infusion site phlebitis (2.2%) and nausea (2.2%).
Slovenian: Najpogostejši neželeni učinki, ki so se pojavili pri 322 bolnikih v združenih preskušanjih 3. faze, so bili glavobol (8,1 %), diareja (4,7 %), flebitis na mestu infundiranja (2,2 %) in navzea (2,2 %).
English: Vaborem has moderate influence on the ability to drive and use machines.
Slovenian: Zdravilo Vaborem ima zmeren vpliv na sposobnost vožnje in upravljanja strojev.
English: Unknown: (frequency cannot be estimated from the available data)
Slovenian: Ni znano (iz razpoložljivih podatkov pogostnosti ni mogoče oceniti)
English: It is unknown whether vaborbactam is excreted in human milk or animal milk.
Slovenian: Ni znano, ali se vaborbaktam izloča v materino mleko pri ljudeh ali živalih.
English: Although Vaborem can fight certain bacteria, there is a possibility that you may get a different infection caused by another organism during or after your treatment.
Slovenian: Čeprav zdravilo Vaborem deluje proti določenim bakterijam, obstaja možnost, da se med zdravljenjem ali po njem pri vas razvije drugačna okužba, ki jo povzroča drug organizem.
English: The concentration time profiles are similar for ELF and plasma.
Slovenian: Profila koncentracije po času v bronhialni epitelijski tekočini (ELF) in plazmi sta podobna.
English: In one additional patient, a serious adverse reaction of infusion related reaction was reported (0.3%).
Slovenian: Poleg tega so pri tretjem bolniku poročali o resnem neželenem učinku v obliki reakcije, povezane z infuzijo (0,3 %).
English: Vaborem will be given to you by a doctor or nurse by infusion (a drip) into a vein, lasting 3 hours.
Slovenian: Zdravilo Vaborem vam bosta dala zdravnik ali medicinska sestra z infuzijo v veno, ki bo trajala 3 ure.
English: Antiglobulin test (Coombs test) seroconversion
Slovenian: Serokonverzija pri antiglobulinskem testu (Coombsov test)
English: • A severe and very low white blood cell count - shown in blood tests
Slovenian: • resno, zelo zmanjšano število belih krvnih celic - razvidno iz krvnih preiskav
English: Other side effects Tell your doctor or nurse if you notice any of the following side effects:
Slovenian: Drugi neželeni učinki Obvestite zdravnika ali medicinsko sestro, če opazite katerega koli od naslednjih neželenih učinkov:
English: The terminal half-life (t½) is 2.30 hours and 2.25 hours for meropenem and vaborbactam, respectively.
Slovenian: Končni razpolovni čas (t½) je 2,30 ure za meropenem in 2,25 ure za vaborbaktam.
English: The chemical and physical in-use stability has been demonstrated for up to 4 hours at 25 °C or within 22 hours at 2 - 8 °C.
Slovenian: Dokazana je kemijska in fizikalna stabilnost med uporabo največ 4 ure pri temperaturi 25 °C ali največ 22 ur pri temperaturi 2-8 °C.
English: Severe adverse reactions were observed in two patients (0.6 %), one infusion related reaction and one blood alkaline phosphatase increased respectively.
Slovenian: Hude neželene učinke so opazili pri dveh bolnikih (0,6 %); pri enem se je pojavila reakcija, povezana z infuzijo, pri drugem pa zvišanje koncentracije alkalne fosfataze v krvi.
English: Anaerobic micro-organisms:
Slovenian: Anaerobni mikroorganizmi:
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 20 November 2018
Slovenian: ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET Z ZDRAVILOM EU/1/18/1334/001 DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Z ZDRAVILOM Datum prve odobritve: 20. novembra 2018
English: Patients taking CYP2D6 substrates with narrow therapeutic index (e.g. dextromethorphan, desipramine, venlafaxine, and metoprolol) should be monitored for signs of toxicity.
Slovenian: Bolnike, ki jemljejo substrate CYP2D6 z ozkim terapevtskim indeksom (npr. dekstrometorfan, dezipramin, venlafaksin in metoprolol), je treba spremljati glede znakov toksičnosti.
English: In vitro data suggest that vaborbactam may inhibit CYP2D6, and a risk for increased plasma concentrations of sensitive CYP2D6 substrates in vivo cannot be excluded.
Slovenian: Podatki in vitro kažejo, da lahko vaborbaktam zavira CYP2D6, in tveganja za zvišane plazemske koncentracije občutljivih substratov CYP2D6 in vivo ni mogoče izključiti.
English: The recommended dose is 2 vials (a total of 2 g meropenem and 2 g vaborbactam), given every 8 hours.
Slovenian: Priporočeni odmerek je 2 viali (skupaj 2 g meropenema in 2 g vaborbaktama) in se daje na vsakih 8 ur.
English: The plasma protein binding of vaborbactam is approximately 33%.
Slovenian: Vezava vaborbaktama na beljakovine v plazmi je približno 33 %.
English: • a medicine to treat issues with getting an erection in men or to treat high blood pressure in the lungs called sildenafil
Slovenian: • zdravilo za zdravljenje težav z doseganjem erekcije pri moških ali za zdravljenje visokega krvnega tlaka v pljučih, ki se imenuje sildenafil;
English: (including penicillins, cephalosporins or monobactams).
Slovenian: (vključno s penicilini, cefalosporini ali monobaktami).
English: Менарини България EООД тел.
Slovenian: Менарини България EООД
English: Your doctor may take some blood to check how well your liver is working while taking the medicine.
Slovenian: Zdravnik vam bo morda odvzel vzorec krvi, da bi preveril, kako dobro delujejo vaša jetra med jemanjem tega zdravila.
English: The mean non-renal clearance for meropenem was 4.8 L/h, which comprises both fecal elimination (~2% of the dose) and degradation due to hydrolysis.
Slovenian: Srednji neledvični očistek meropenema je bil 4,8 l/h, kar vključuje fekalno izločanje (~ 2 % odmerka) in razgradnjo zaradi hidrolize.
English: • a medicine used to treat seizures or given prior to a surgery or certain examinations inside your body such as a colonoscopy, called midazolam
Slovenian: • zdravilo, ki se uporablja za zdravljenje epileptičnih napadov ali se daje pred operacijo ali določenimi pregledi v notranjosti telesa (kot je kolonoskopija), ki se imenuje midazolam;
English: Meropenem is a substrate of OAT1 and OAT3 and as such, probenecid competes with meropenem for active tubular secretion and thus inhibits the renal excretion of meropenem.
Slovenian: Ker je meropenem substrat OAT1 in OAT3, probenecid tekmuje z njim za aktivno tubularno izločanje in tako zavira izločanje meropenema skozi ledvice.
English: Vaborem is available in packs containing 6 vials.
Slovenian: Zdravilo Vaborem je na voljo v pakiranjih, ki vsebujejo po 6 vial.
English: It is important that you tell your doctor if you are breast-feeding or if you intend to breast-feed before receiving Vaborem.
Slovenian: Pomembno je, da zdravniku poveste, če dojite ali nameravate dojiti, preden prejmete zdravilo Vaborem.
English: Meropenem does not have activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MRSE) or vancomycin-resistant Enterococci (VRE).
Slovenian: Meropenem ne deluje na proti meticilinu odporne organizme Staphylococcus aureus (MRSA) in Staphylococcus epidermidis (MRSE), niti na proti vankomicinu odporne enterokoke (VRE).
English: This product contains approximately 250 mg of sodium per vial.
Slovenian: To zdravilo vsebuje približno 250 mg natrija na vialo.
English: Limited post-marketing experience with meropenem alone indicates that if adverse reactions occur following overdose, they are consistent with the adverse reaction profile described in section 4.8, are generally mild in severity and resolve on withdrawal or dose reduction.
Slovenian: Glede na omejene izkušnje iz obdobja trženja samega meropenema so neželeni učinki po prevelikem odmerjanju, če se pojavijo, skladni s profilom neželenih učinkov, ki je opisan v poglavju 4.8, na splošno blagi po resnosti in izginejo po odtegnitvi zdravila ali zmanjšanju odmerka.
English: Recommended Dosage Regimen2
Slovenian: Priporočeni režim odmerjanja
English: Vaborem is not chemically compatible with glucose-containing solutions.
Slovenian: Zdravilo Vaborem kemijsko ni kompatibilno z raztopinami, ki vsebujejo glukozo.
English: There have been many reports of increases in the anticoagulant effects of orally administered anticoagulants, including warfarin in patients, who are concomitantly receiving antibacterial agents.
Slovenian: Na voljo so številna poročila o povečanju antikoagulacijskih učinkov peroralno uporabljenih antikoagulansov, vključno z varfarinom, pri bolnikih, ki so sočasno prejemali protibakterijske učinkovine.
English: This test looks for the presence of antibodies that can destroy red blood cells or may be affected by the response of your immune system to Vaborem.
Slovenian: Ta test zaznava prisotnost protiteles, ki lahko uničijo rdeče krvne celice, odziv vašega imunskega sistema na zdravilo Vaborem pa lahko vpliva na rezultat testa.
English: Hypersensitivity to any carbapenem antibacterial agent.
Slovenian: Preobčutljivost za kateri koli drug karbapenemski antibiotik.
English: Берлин-Хеми/А.
Slovenian: България Берлин-Хеми/А.
English: The mean renal clearance for meropenem was 7.7 L/h.
Slovenian: Srednji ledvični očistek meropenema je bil 7,7 l/h.
English: This should be taken into consideration while treating patients on a controlled sodium diet.
Slovenian: To je treba upoštevati pri zdravljenju bolnikov, ki se morajo držati diete z nadzorovanim vnosom natrija.
English: In vitro studies demonstrated no antagonism between meropenem/vaborbactam and levofloxacin, tigecycline, polymyxin, amikacin, vancomycin, azithromycin, daptomycin or linezolid.
Slovenian: Študije in vitro niso pokazale nobenega antagonizma med meropenemom/vaborbaktamom in levofloksacinom, tigeciklinom, polimiksinom, amikacinom, vankomicinom, azitromicinom, daptomicinom ali linezolidom.