FrancophonIA/ELRC3.0 huggingface dataset:
English: If you are not sure about giving the injection or you have any questions, please ask your doctor or nurse for help.
Croatian: Ako niste sigurni kako dati injekciju ili imate dodatnih pitanja, molimo obratite se svom liječniku ili medicinskoj sestri za pomoć.
English: Once a syringe has been removed from the refrigerator and has reached room temperature (up to 25°C) it must either be used within 3 days or disposed of.
Croatian: Nakon što ste jednom izvadili štrcaljku iz hladnjaka i ona je postigla sobnu temperaturu (do 25 °C) morate je primijeniti u roku od 3 dana ili je baciti.
English: Of the patients who achieved the target, 90% did so on a 3 times-per-week dosing regimen.
Croatian: Od bolesnika koji su postigli ciljnu vrijednost, 90 % njih ju je postiglo pri režimu doziranja 3 puta tjedno.
English: This is of uncertain significance in the clinical situation.
Croatian: Značenje tih nalaza za kliničku situaciju je neizvjesno.
English: If blood pressure cannot be controlled, epoetin alfa treatment should be discontinued.
Croatian: Ako se krvni tlak ne može kontrolirati, liječenje epoetinom alfa treba prekinuti.
English: • Do not use this medicine after the expiry date which is stated on the label and carton after EXP.
Croatian: • Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na naljepnici i kutiji iza oznake „EXP“.
English: • For adults and children Epoetin alfa HEXAL is given as an injection either into a vein (intravenously) or a tube that goes into a vein.
Croatian: • Odraslima i djeci Epoetin alfa HEXAL se daje ili kao injekcija u venu (intravenski) ili kroz cjevčicu koja ulazi u venu.
English: • unusual tiredness,
Croatian: • neuobičajen umor,
English: For patients on peritoneal dialysis Epoetin alfa HEXAL may be given twice a week.
Croatian: Bolesnicima na peritonealnoj dijalizi Epoetin alfa HEXAL se može davati dva puta tjedno.
English: In some studies, the double-blind phase was followed by an open-label phase during which all patients received epoetin alfa and a maintenance of effect was observed.
Croatian: U nekim ispitivanjima je nakon dvostruko slijepe faze slijedila otvorena faza tijekom koje su svi bolesnici primali epoetin alfa i uočeno je održavanje učinka.
English: Medicinal products that decrease erythropoiesis may decrease the response to epoetin alfa.
Croatian: Lijekovi koji smanjuju eritropoezu mogu smanjiti odgovor na epoetin alfa.
English: The dose of Epoetin alfa HEXAL you receive is based on your body weight in kilograms.
Croatian: Doza Epoetin alfa HEXALa koju primate temelji se na Vašoj tjelesnoj težini u kilogramima.
English: 8.4 micrograms 16.8 micrograms
Croatian: 8,4 mikrograma 16,8 mikrograma
English: • Only use Epoetin alfa HEXAL if it has been stored correctly - see section 5, How to store
Croatian: • Primijenite Epoetin alfa HEXAL samo ako je bio čuvan na ispravan način - vidjeti dio 5,
English: • Either into a vein or a tube that goes into a vein (intravenously)
Croatian: • u venu ili cjevčicu koja ulazi u venu (intravenski)
English: Patients from the group treated with epoetin alfa were also enrolled in an open-label extension study which demonstrated improvements in their quality of life that were maintained for an additional 12 months.
Croatian: Bolesnici iz skupine liječene epoetinom alfa bili su također uključeni u otvoreni produžetak ispitivanja koji je pokazao da se poboljšanje u kvaliteti njihovog života održalo tijekom dodatnih 12 mjeseci.
English: It is important to tell your doctor if any of the following apply to you.
Croatian: Važno je obavijestiti liječnika ako se nešto od sljedećeg odnosi na Vas.
English: Please discuss this with your doctor.
Croatian: Molimo porazgovarajte o tome sa svojim liječnikom.
English: Screening sEPO < 200 mU/mL (N) Haemoglobin (g/L) N
Croatian: Probir sEPO < 200 mU/ml (N) Hemoglobin (g/l) N
English: • a swollen face, lips, mouth, tongue or throat,
Croatian: • nateklo lice, usne, usta, jezik ili grlo, • otežano gutanje ili disanje,
English: Your healthcare professional will always record the exact product you are using.
Croatian: Liječnik ili medicinska sestra će uvijek točno zabilježiti koji lijek uzimate.
English: The haemoglobin response varies between patients and may be impacted by iron stores and the presence of concurrent medical problems.
Croatian: Odgovor hemoglobina se razlikuje među bolesnicima i može biti pod utjecajem zaliha željeza i istovremeno prisutnih zdravstvenih problema.
English: If the product has been shaken vigorously, don't use it.
Croatian: Ako se lijek snažno protresao, nemojte ga primijeniti.
English: Overdosage of epoetin alfa may produce effects that are extensions of the pharmacological effects of the hormone.
Croatian: Predoziranje epoetinom alfa može proizvesti učinke koji su nastavak farmakoloških učinaka ovog hormona.
English: Epoetin alfa should be used with caution in the presence of untreated, inadequately treated or poorly controllable hypertension.
Croatian: Epoetin alfa treba primjenjivati s oprezom kod neliječene, neadekvatno liječene ili loše kontrolirane hipertenzije.
English: Each graduation ring corresponds to a volume of 0.1 mL.
Croatian: Jedan prsten odgovara volumenu od 0,1 ml.
English: It is recommended that the platelet count is regularly monitored during the first 8 weeks of therapy.
Croatian: Preporučuje se redovito praćenje broja trombocita tijekom prvih 8 tjedana terapije.
English: A patient-level data analysis has also been performed on more than 13,900 cancer patients (chemo-, radio-, chemoradio-, or no therapy) participating in 53 controlled clinical trials involving several epoetins.
Croatian: Provedena je i analiza podataka na razini bolesnika na više od 13 900 onkoloških bolesnika (kemo-, radio-, kemoradioterapija ili bez ikakve terapije) koji su sudjelovali u 53 kontrolirana klinička ispitivanja koja su uključivala nekoliko epoetina.
English: EPO is involved in all phases of erythroid development, and has its principal effect at the level of erythroid precursors.
Croatian: EPO je uključen u sve faze razvoja eritrocita i primarno djeluje na razini eritrocitnih prekursora.
English: < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000), not known (cannot be estimated from the available data).
Croatian: Procjena učestalosti: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Your doctor may decide to increase your heparin dose during dialysis.
Croatian: Liječnik će Vam možda povisiti dozu heparina tijekom dijalize.
English: Mean Median Range 95% CI for mean Prior Transfusions N Yes
Croatian: Srednja vrijednost Medijan Raspon 95 % CI za srednju vrijednost Prethodne transfuzije N Da
English: ANNEX II A. MANUFACTURERS OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURER RESPONSIBLE FOR BATCH RELEASE B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE C. OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION D. CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE USE OF THE MEDICINAL PRODUCT
Croatian: PRILOG II. A. PROIZVOĐAČI BIOLOŠKE DJELATNE TVARI I PROIZVOĐAČ ODGOVORAN ZA PUŠTANJE SERIJE LIJEKA U PROMET B. UVJETI ILI OGRANIČENJA VEZANI UZ OPSKRBU I PRIMJENU C. OSTALI UVJETI I ZAHTJEVI ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET
English: After EPO binds to its cell surface receptor, it activates signal transduction pathways that interfere with apoptosis and stimulates erythroid cell proliferation.
Croatian: Nakon što se EPO veže na površinski receptor stanice, aktivira signalne putove transdukcije koji koče apoptozu i stimulira proliferaciju eritroidnih stanica.
English: • Ensure that you only inject the amount of liquid as instructed by your doctor or nurse.
Croatian: • Pazite da ubrizgate samo onu količinu tekućine kako su Vas uputili liječnik ili medicinska sestra.
English: If the medicinal product has not been used at the end of this period, it should be disposed of.
Croatian: Ako se lijek ne primijeni u tom razdoblju, treba ga baciti.
English: Insert the needle into the skin fold with a quick, firm action.
Croatian: Uvedite iglu u nabor kože brzim, sigurnim pokretom.
English: • The usual starting dose of Epoetin alfa HEXAL for adults and children is 50 International Units (IU) per kilogram (/kg) of body weight given three times a week.
Croatian: • Uobičajena početna doza Epoetin alfa HEXALa za odrasle i djecu je 50 međunarodnih jedinica (IU) po kilogramu (/kg) tjelesne težine i daje se tri puta tjedno.
English: In the four placebo-controlled studies the hazard ratios for overall survival ranged between 1.25 and 2.47 in favour of controls.
Croatian: U četiri placebom kontrolirana ispitivanja, omjeri hazarda za ukupno preživljenje kretali su se u rasponu od 1,25 do 2,47 u korist kontrolnih ispitanika.
English: • high blood pressure;
Croatian: • povišenog krvnog tlaka;
English: Take special care with other products that stimulate red blood cell production:
Croatian: Budite posebno oprezni s drugim lijekovima koji potiču stvaranje crvenih krvnih stanica:
English: If Epoetin alfa HEXAL is injected under the skin (subcutaneously), the amount injected is not normally more than one millilitre (1 mL) in a single injection.
Croatian: Ako se Epoetin alfa HEXAL ubrzigava pod kožu (supkutano), ubrizgana količina obično nije veća od jednog mililitra (1 ml) u jednoj injekciji.
English: • Blood clots (including deep vein thrombosis and embolism) that may require urgent treatment.
Croatian: • Krvni ugrušci (uključujući duboku vensku trombozu i emboliju) koji mogu zahtijevati hitno liječenje.
English: If it occurs, appropriate dose adjustment should be made as provided.
Croatian: Ako do njega dođe, potrebno je napraviti odgovarajuću prilagodbu doze kako je navedeno.
English: Epoetin alfa HEXAL has no or negligible influence on the ability to drive and use machines.
Croatian: Epoetin alfa HEXAL ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Dose increases and decreases should be done one dosing step at a time (see diagram below).
Croatian: Povećanje i smanjenje doze mora se provoditi postepeno, po jedan korak u doziranju (pogledajte dijagram u nastavku).
English: After 52 weeks, 57% of patients remained in the study, receiving a median dose of 200 IU/kg/week.
Croatian: Nakon 52 tjedna, 57 % bolesnika ostalo je u ispitivanju, a medijan doze koju su primali bio je 200 IU/kg/tjedno.
English: Two subjects had significant risk factors (atrial fibrillation, heart failure and thrombophlebitis).
Croatian: Dva su ispitanika imala značajne faktore rizika (fibrilacija atrija, zatajenje srca i tromboflebitis).
English: • Do not freeze or shake.
Croatian: • Ne zamrzavati ili tresti.
English: The decision to administer recombinant erythropoietin treatment should be based on a benefit-risk assessment with the participation of the individual patient, which should take into account the specific clinical context.
Croatian: Odluku o primjeni liječenja rekombinantnim eritropoetinom treba temeljiti na procjeni omjera koristi i rizika uz sudjelovanje pojedinog bolesnika, a treba uzeti u obzir i specifični klinički kontekst.
English: In view of the above, in some clinical situations blood transfusion should be the preferred treatment for the management of anaemia in patients with cancer.
Croatian: S obzirom na gore navedeno, u nekim kliničkim situacijama, transfuziji krvi treba dati prednost u liječenju anemije u bolesnika s rakom.
English: Remove one syringe from the pack and remove the protective cap from the injection needle.
Croatian: Izvadite jednu štrcaljku iz pakovanja i uklonite zaštitni zatvarač s injekcijske igle.
English: Some people, depending on why they need Epoetin alfa HEXAL treatment, may later learn how to inject themselves under the skin: see
Croatian: Pojedine osobe, ovisno o tome zašto im treba liječenje Epoetin alfa HEXALom, mogu kasnije naučiti kako da same sebi daju injekciju pod kožu:
English: Additionally, cerebrovascular accidents (including cerebral infarction, cerebral haemorrhage and transient ischaemic attacks) have been reported.
Croatian: Pored toga, prijavljeni su cerebrovaskularni incidenti (uključujući moždani udar, moždano krvarenje i tranzitorne ishemijske atake).
English: Decreasing the dose by one dosing step should be considered if there is a rapid increase in haemoglobin (> 2 g/dL over 4 weeks).
Croatian: Smanjenje doze za jedan korak u doziranju treba se razmotriti u slučaju brzog povećanja hemoglobina (> 2 g/dl unutar 4 tjedna).
English: Bone marrow fibrosis is a known complication of chronic renal failure in humans and may be related to secondary hyperparathyroidism or unknown factors.
Croatian: Fibroza koštane srži je poznata komplikacija kroničnog zatajenja bubrega u ljudi i može biti povezana sa sekundarnim hiperparatiroidizmom ili nepoznatim faktorima.
English: • Redness, burning and pain at the site of injection.
Croatian: • Crvenilo, pečenje i bol na mjestu injekcije
English: Haemoglobin levels should be monitored regularly.
Croatian: Potrebno je redovito nadzirati razine hemoglobina.
English: Following subcutaneous injection, serum levels of epoetin alfa reach a peak between 12 and 18 hours post-dose.
Croatian: Nakon supkutane injekcije, serumske razine epoetina alfa dosežu vršnu vrijednost 12 do 18 sati nakon primjene doze.
English: Iron supplements and other blood stimulants may increase the effectiveness of Epoetin alfa HEXAL.
Croatian: Dodaci sa željezom i drugi pripravci za jačanje krvi mogu povećati djelotvornost Epoetin alfa HEXALa.
English: In animal studies, epoetin alfa has been shown to decrease foetal body weight, delay ossification and increase foetal mortality when given in weekly doses of approximately 20 times the recommended human weekly dose.
Croatian: U ispitivanjima na životinjama pokazalo se da epoetin alfa smanjuje fetalnu tjelesnu težinu, usporava osifikaciju i povećava fetalni mortalitet kada se daje u tjednim dozama približno 20 puta većim od preporučene tjedne doze u ljudi.
English: In clinical trials at starting doses of 50 to 150 IU/kg, three times per week, approximately 95% of all patients responded with a clinically significant increase in haematocrit.
Croatian: U kliničkim ispitivanjima pri početnim dozama od 50 do 150 IU/kg tri puta tjedno, približno 95 % svih bolesnika odgovorilo je klinički značajnim povećanjem hematokrita.
English: Clean the skin at the injection site using an alcohol wipe.
Croatian: Očistite kožu na mjestu primjene injekcije pomoću tupfera natopljenog alkoholom.
English: • if there has been a refrigerator failure,
Croatian: • je došlo do kvara hladnjaka,
English: Controlled clinical trials have not shown significant benefits attributable to the administration of epoetins when haemoglobin concentration is increased beyond the level necessary to control symptoms of anaemia and to avoid blood transfusion.
Croatian: Kontrolirana klinička ispitivanja nisu pokazala značajne koristi koje bi se mogle pripisati primjeni epoetina kada se koncentracija hemoglobina povećala iznad razine neophodne za kontrolu simptoma anemije i izbjegavanje transfuzije krvi.
English: Overall survival outcome in the trials could not be satisfactorily explained by differences in the incidence of thrombosis and related complications between those given recombinant human erythropoietin and those in the control group.
Croatian: Ishod ukupnog preživljenja u ispitivanjima nije se mogao zadovoljavajuće objasniti razlikama u incidenciji tromboze i s njom povezanim komplikacijama između onih koji su dobivali rekombinantni humani eritropoetin i onih u kontrolnoj skupini.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from therapy with epoetin alfa taking into account the benefit of breast-feeding for the child and the benefit of epoetin alfa therapy for the woman.
Croatian: Potrebno je odlučiti da li prekinuti dojenje ili prekinuti liječenje/suzdržati se od liječenja epoetinom alfa uzimajući u obzir korist dojenja za dijete i korist liječenja epoetinom alfa za ženu.
English: The median time to target was 11 weeks and the median dose at target was 150 IU/kg/week.
Croatian: Medijan vremena do postizanja ciljne vrijednosti bio je 11 tjedana, a medijan doze pri tome je bio 150 IU/kg/tjedno.
English: The mean volume of distribution was 49.3 mL/kg after intravenous doses of 50 and 100 IU/kg in healthy subjects.
Croatian: Srednja vrijednost volumena distribucije bila je 49,3 ml/kg nakon intravenske doze od 50 i 100 IU/kg u zdravih ispitanika.
English: Your doctor has carried out blood tests and decided you need Epoetin alfa HEXAL.
Croatian: Liječnik Vam je napravio krvne pretrage i odlučio da Vam je potreban Epoetin alfa HEXAL.
English: Do not administer Epoetin alfa HEXAL by intravenous infusion or in conjunction with other medicinal product solutions (please refer to section 6.6 for further information).
Croatian: Nemojte primjenjivati Epoetin alfa HEXAL intravenskom infuzijom ili zajedno s otopinom drugog lijeka (vidjeti dio 6.6 za dodatne informacije).
English: Pack of 1 or 6 syringes.
Croatian: Pakiranje od 1 ili 6 štrcaljki.
English: There are no studies assessing the potential effect of epoetin alfa on male or female fertility.
Croatian: Nema ispitivanja u kojima se procjenjivao mogući utjecaj epoetina alfa na plodnost u muškaraca i žena.
English: Epoetin alfa HEXAL is provided with or without a needle safety guard and you will be shown how to use this by your doctor or nurse.
Croatian: Epoetin alfa HEXAL je dostupan sa ili bez zaštitnog mehanizma za iglu i Vaš liječnik ili medicinska sestra će Vam pokazati kako se koristi.
English: In patients with chronic renal failure, maintenance haemoglobin concentration should not exceed the upper limit of the haemoglobin concentration range as recommended in section 4.2.
Croatian: U bolesnika s kroničnim zatajenjem bubrega, održavana koncentracija hemoglobina ne smije prekoračiti gornju granicu raspona koncentracije hemoglobina kao što je preporučeno u dijelu 4.2.
English: If possible, iron supplementation should be initiated prior to starting epoetin alfa therapy to achieve adequate iron stores.
Croatian: Ako je moguće, nadoknadu željeza treba započeti prije početka terapije epoetinom alfa kako bi se osigurale odgovarajuće zalihe željeza.
English: Pre-filled syringes (glass type I), with or without a needle safety guard, with plunger stopper (Teflon-faced rubber) sealed in a blister.
Croatian: Napunjene štrcaljke (staklo tip I), sa ili bez sigurnosnog štitnika za iglu, s čepom klipa (teflonom prekrivena guma), zatvorene u blisteru.
English: • Swelling of the ankles, feet or fingers.
Croatian: • Oticanje gležnjeva, stopala ili prstiju na rukama
English: Pack of 1, 4 or 6 syringes.
Croatian: Pakiranje od 1, 4 ili 6 štrcaljki.
English: 168.0 micrograms 252.0 micrograms 336.0 micrograms
Croatian: 168,0 mikrograma 252,0 mikrograma 336,0 mikrograma
English: Rare side effects These may affect up to 1 in 1,000 people.
Croatian: Rijetke nuspojave Mogu se javiti u do 1 na 1000 osoba.
English: Erythropoietin (EPO) is a glycoprotein hormone produced primarily by the kidney in response to hypoxia and is the key regulator of red blood cell (RBC) production.
Croatian: Eritropoetin (EPO) je glikoproteinski hormon koji se primarno proizvodi u bubrezima kao odgovor na hipoksiju i ključni je regulator proizvodnje crvenih krvnih stanica (CKS).
English: Tell your doctor or nurse immediately if you are aware of any of these effects, or if you notice any other effects while you are receiving treatment with Epoetin alfa HEXAL.
Croatian: Odmah obavijestite liječnika ili medicinsku sestru ako primijetite bilo koju od ovih nuspojava ili ako primijetite bilo kakve druge učinke dok primate Epoetin alfa HEXAL.
English: • anaemia from other causes;
Croatian: • bolesti jetre; • anemije zbog drugih uzroka;
English: Your doctor will monitor your blood pressure regularly while you are using Epoetin alfa HEXAL.
Croatian: Liječnik će Vam redovito nadzirati krvni tlak dok primate Epoetin alfa HEXAL.
English: During the maintenance phase, Epoetin alfa HEXAL can be administered either 3 times per week, and in the case of subcutaneous administration, once weekly or once every 2 weeks.
Croatian: Tijekom faze održavanja Epoetin alfa HEXAL se može primjenjivati ili 3 puta tjedno, a u slučaju supkutane primjene jednom tjedno ili jednom svaka 2 tjedna.
English: In cell cultures of human bone marrow cells, epoetin alfa stimulates erythropoiesis specifically and does not affect leucopoiesis.
Croatian: U staničnim kulturama stanica ljudske koštane srži, epoetin alfa specifično stimulira eritripoezu i ne utječe na leukopoezu.
English: The absolute bioavailability of subcutaneous injectable epoetin alfa is approximately 20% in healthy subjects.
Croatian: Apsolutna bioraspoloživost supkutano injiciranog epoetina alfa je približno 20 % u zdravih ispitanika.
English: What Epoetin alfa HEXAL is and what it is used for
Croatian: Što je Epoetin alfa HEXAL i za što se koristi
English: Very rarely, development of or exacerbation of porphyria has been observed in epoetin alfa-treated patients.
Croatian: Vrlo rijetko je opažen nastanak ili pogoršanje porfirije u bolesnika liječenih epoetinom alfa.
English: After 4 weeks of treatment the time to first transfusion was further increased in the epoetin alfa group (142 vs. 50 days, p = 0.007).
Croatian: Nakon 4 tjedna liječenja vrijeme do prve transfuzije dodatno je povećano u skupini liječenoj epoetinom alfa (142 u odnosu na 50 dana, p = 0,007).
English: If you have kidney disease, you may be short of red blood cells if your kidney does not produce enough erythropoietin (necessary for red cell production).
Croatian: Ako imate bolest bubrega, možda nemate dovoljno crvenih krvnih stanica ako Vaši bubrezi ne stvaraju dovoljno eritropoetina (neophodan za stvaranje crvenih krvnih stanica).
English: This includes patients on dialysis and patients not yet on dialysis.
Croatian: To se odnosi na bolesnike na dijalizi i bolesnike koji još nisu na dijalizi.
English: Epoetin alfa therapy reduced the risk of exposure to allogeneic blood by 50% compared to patients not receiving epoetin alfa.
Croatian: Terapija epoetinom alfa smanjila je rizik od izloženosti alogenoj krvi za 50 % u odnosu na bolesnike koji nisu primali epoetin alfa.
English: These may affect more than 1 in 10 people.
Croatian: Mogu se javiti kod više od 1 na 10 osoba.
English: Conflicting reports in the literature, based on in vitro findings from human tumour samples, suggest erythropoietins may play a role as tumour proliferators.
Croatian: Proturječna izvješća u literaturi temeljena na in vitro nalazima iz uzoraka tumora u ljudi, navode moguću ulogu eritropoetina kao tumorskih proliferatora.
English: In most cases, the ferritin values in the serum fall simultaneously with the rise in packed cell volume.
Croatian: U većini slučajeva vrijednosti feritina u serumu opadaju simultano s povišenjem hematokrita.
English: If you are a cancer patient be aware that products that stimulate red blood cell production (like Epoetin alfa HEXAL) may act as a growth factor and therefore in theory may affect the progression of your cancer.
Croatian: Ako ste bolesnik koji ima rak morate znati da lijekovi koji potiču stvaranje crvenih krvnih stanica (kao Epoetin alfa HEXAL) mogu djelovati kao čimbenici rasta i tako teoretski mogu utjecati na daljnje napredovanje raka.
English: Your doctor will help you to decide if Epoetin alfa HEXAL is suitable for you.
Croatian: Vaš liječnik će Vam pomoći odlučiti je li Epoetin alfa HEXAL pogodan za Vas.
English: • Your doctor may initiate treatment with Epoetin alfa HEXAL if your haemoglobin is 10 g/dL or less.
Croatian: • Liječnik može započeti liječenje Epoetin alfa HEXALom ako Vam je vrijednost hemoglobina 10 g/dl ili manje.
English: In repeated dose toxicological studies in dogs and rats, but not in monkeys, epoetin alfa therapy was associated with subclinical bone marrow fibrosis.
Croatian: U ispitivanjima toksičnosti ponovljenih doza u pasa i štakora, ali ne i u majmuna, terapija epoetinom alfa bila je povezana sa subkliničkom fibrozom koštane srži.