FrancophonIA/ELRC3.0 huggingface dataset:
English: Development or exacerbation of diabetes occasionally associated with ketoacidosis or coma, including some fatal cases (see section 4.4) 11
Croatian: glikozurija pojačan apetit razvoj ili egzacerbacija dijabetesa, ponekad povezana s ketoacidozom ili komom, uključujući i neke slučajeve sa smrtnim ishodom (vidjeti dio 4.4)11
English: If you get any side effects, talk to your doctor or pharmacist.
Croatian: Ako imate bilo koji od gornjih simptoma, odmah se obratite svom liječniku ili bolnici.
English: Only take other medicines while you are on Olazax Disperzi if your doctor tells you that you can. You might feel drowsy if Olazax Disperzi is taken in combination with antidepressants or medicines taken for anxiety or to help you sleep (tranquillisers).
Croatian: Ako uzimate Olazax Disperzi u kombinaciji s antidepresivima, lijekovima za tjeskobu ili lijekovima koji Vam pomažu zaspati (trankvilizeri), možete se osjećati omamljeno.
English: Changes in total fasting cholesterol levels from borderline at baseline (≥ 5.17-< 6.2 mmol/l) to high (≥ 6.2 mmol/l) were very common.
Croatian: Promjene ukupnog kolesterola natašte od početnih graničnih vrijednosti (≥ 5,17-< 6,2 mmol/l) do visokih vrijednosti (≥ 6,2 mmol/l) bile su vrlo česte.
English: High Gamma Glutamyltransferase10 High uric acid 10
Croatian: visoka gama glutamiltransferaza1
English: What Olazax Disperzi is and what it is used for
Croatian: Što je Olanzapin Glenmark Europe i za što se koristi
English: Olazax Disperzi 5 mg orodispersible tablets
Croatian: Olazax Disperzi 5 mg raspadljive tablete za usta
English: In placebo-controlled clinical trials (6-12 weeks duration) of elderly patients (mean age 78 years) with dementia-related psychosis and/or disturbed behaviours, there was a 2-fold increase in the incidence of death in olanzapine-treated patients compared to patients treated with placebo (3.5 % verses 1.5 %, respectively).
Croatian: (srednja vrijednost dobi 78 godina) s psihozom i/ili poremećajima ponašanja uzrokovanima demencijom zabilježeno je dvostruko povećanje incidencije smrtnosti u bolesnika liječenih olanzapinom u usporedbi s bolesnicima koji su primali placebo (3,5% naspram 1,5%).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each orodispersible tablet contains 7.5 mg olanzapine.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Svaka raspadljiva tableta za usta sadrži 7,5 mg olanzapina.
English: If you stop taking Olazax Disperzi
Croatian: Nemojte uzimati Olazax Disperzi
English: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Croatian: Poremećaji kože i potkožnog tkiva osip reakcija fotoosjetljivosti alopecija reakcija na lijek uz eozinofiliju i sistemske simptome (DRESS)
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 7.5 mg orodispersible tablets
Croatian: NAZIV GOTOVOG LIJEKA Olazax Disperzi 7,5 mg raspadljive tablete za usta
English: SPECIAL STORAGE CONDITIONS Store below 30C
Croatian: ROK VALJANOSTI Rok valjanosti POSEBNE MJERE ČUVANJA Čuvati na temperaturi ispod 30ºC.
English: INFORMATION IN BRAILLE Olazax Disperzi 7.5 mg orodispersible tablets 17.
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Olazax Disperzi 7,5 mg raspadljive tablete za usta
English: Transient, asymptomatic elevations of hepatic aminotransferases , alanine transferase (ALT), aspartatetransferase (AST) have been seen commonly, especially in early treatment.
Croatian: Često su uočeni prolazni asimptomatski porasti vrijednosti jetrenih aminotransferaza, ALT i AST, osobito u ranoj fazi liječenja.
English: Yellow coloured circular flat bevelled edge orodispersible tablets with ‘B' debossed on one side.
Croatian: Žute, okrugle, plosnate raspadljive tablete za usta kosih rubova, s utisnutom oznakom ‘B' na jednoj strani.
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 7.5 mg orodispersible tablets Olanzapine
Croatian: Olazax Disperzi 7,5 mg raspadljive tablete za usta olanzapin
English: Dystonia (including oculogyration)11
Croatian: distonija (uključujući okulogiraciju)11 tardivna diskinezija11 amnezija9
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER Glenmark Pharmaceuticals s.r.o.
Croatian: 11. IME I ADRESA NOSITELJA ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET Glenmark Pharmaceuticals s.r.o.
English: Excipient with known effect: Each orodispersible tablet contains 0.46 mg aspartame For the full list of excipients see section 6.1
Croatian: Pomoćna tvar s poznatim učinkom: Svaka raspadljiva tableta za usta sadrži 0,46 mg aspartama.
English: MARKETING AUTHORISATION HOLDER Glenmark Pharmaceuticals s.r.o.
Croatian: ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET Glenmark Pharmaceuticals s.r.o.
English: Management
Croatian: PROMET
English: Yellow coloured circular flat bevelled edge orodispersible tablets with ‘C' debossed on one side.
Croatian: Žute, okrugle, plosnate raspadljive tablete za usta kosih rubova, s utisnutom oznakom ‘C' na jednoj strani.
English: Excipient with known effect: Each orodispersible tablet contains 0.69 mg aspartame For the full list of excipients see section 6.1
Croatian: Pomoćna tvar s poznatim učinkom: Svaka raspadljiva tableta za usta sadrži 0,69 mg aspartama.
English: INFORMATION IN BRAILLE Olazax Disperzi 10 mg orodispersible tablets 17.
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Olazax Disperzi 10 mg raspadljive tablete za usta
English: INFORMATION IN BRAILLE Olazax Disperzi 15 mg orodispersible tablets 17.
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Olazax Disperzi 15 mg raspadljive tablete za usta
English: Excipient with known effect: Each orodispersible tablet contains 0.23 mg aspartame For the full list of excipients see section 6.1
Croatian: Pomoćna tvar s poznatim učinkom: Svaka raspadljiva tableta za usta sadrži 0,23 mg aspartama.
English: Amenorrhea Breast enlargement Galactorrhea in females Gynaecomasti a/breast enlargement in males
Croatian: Poremećaji reproduktivnog sustava i dojki erektilna disfunkcija u muškaraca smanjen libido u muškaraca i žena amenoreja povećanje dojki galaktoreja u žena ginekomastija/povećanje dojki u muškaraca prijapizam12
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 20 mg orodispersible tablets
Croatian: NAZIV GOTOVOG LIJEKA Olazax Disperzi 20 mg raspadljive tablete za usta
English: Olazax Disperzi contains the active substance olanzapine.
Croatian: Olanzapin Glenmark Europe sadrži djelatnu tvar olanzapin.
English: Excipient with known effect: Each orodispersible tablet contains 0.35 mg aspartame For the full list of excipients see section 6.1
Croatian: Pomoćna tvar s poznatim učinkom: Svaka raspadljiva tableta za usta sadrži 0,35 mg aspartama.
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 10 mg orodispersible tablets
Croatian: NAZIV GOTOVOG LIJEKA Olazax Disperzi 10 mg raspadljive tablete za usta
English: If you forget to take Olazax Disperzi Take your tablets as soon as you remember.
Croatian: Dok uzimate Olazax Disperzi, druge lijekove uzimajte samo ako Vam liječnik kaže da to možete.
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 5 mg orodispersible tablets
Croatian: NAZIV GOTOVOG LIJEKA Olazax Disperzi 5 mg raspadljive tablete za usta
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 20 mg orodispersible tablets Olanzapine
Croatian: Olazax Disperzi 20 mg raspadljive tablete za usta olanzapin
English: males and females females Gynaecomastia/breast enlargement in males General disorders and administration site conditions Asthenia Fatigue Oedema Pyrexia10
Croatian: Opći poremećaji i reakcije na mjestu primjene astenija umor edem pireksija10
English: Yellow coloured circular flat bevelled edge orodispersible tablets with ‘OL' debossed on one side and ‘E' debossed on other side.
Croatian: Žute, okrugle, plosnate raspadljive tablete za usta kosih rubova, s utisnutom oznakom ‘OL' na jednoj i ‘E' na drugoj strani.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/09/592/001
Croatian: 12. BROJEVI ODOBRENJA ZA STAVLJANJE IJEKA U PROMET EU/1/09/592/001
English: The mean increase in olanzapine AUC was 52 % and 108 % respectively.
Croatian: Srednja vrijednost porasta AUC-a olanzapina iznosila je 52% u žena nepušača, odnosno 108% u muškaraca pušača.
English: categories.
Croatian: BROJEVI
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 10 mg orodispersible tablets Olanzapine
Croatian: Olazax Disperzi 10 mg raspadljive tablete za usta olanzapin
English: Yellow coloured circular flat bevelled edge orodispersible tablets with ‘OL' debossed on one side and ‘F' debossed on other side.
Croatian: Žute, okrugle, plosnate raspadljive tablete za usta kosih rubova, s utisnutom oznakom ‘OL' na jednoj i ‘F' na drugoj strani.
English: Olazax Disperzi 15 mg orodispersible tablets
Croatian: Olazax Disperzi 20 mg raspadljive tablete za usta
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 5 mg orodispersible tablets Olanzapine
Croatian: NAZIV LIJEKA Olazax Disperzi 5 mg raspadljive tablete za usta olanzapin NAVOĐENJE DJELATNE/IH
English: NAME OF THE MEDICINAL PRODUCT Olazax Disperzi 15 mg orodispersible tablets Olanzapine
Croatian: Olazax Disperzi 15 mg raspadljive tablete za usta olanzapin
English: Patients who cannot take phenylalanine should note that Olazax Disperzi contains aspartmae, which is a source of phenylalanine.
Croatian: Olanzapin Glenmark Europe sadrži aspartam Olanzapin Glenmark Europe sadrži izvor fenilalanina.
English: Yellow coloured circular flat bevelled edge tablets with ‘OL' debossed on one side and ‘D' debossed on other side.
Croatian: Žute, okrugle, plosnate raspadljive tablete za usta kosih rubova, s utisnutom oznakom ‘OL' na jednoj i ‘D' na drugoj strani.
English: Aspartame (E 951)
Croatian: 6.1 Popis pomoćnih tvari manitol (E 421) celuloza, mikrokristalična aspartam (E 951)
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each orodispersible tablet contains 20 mg olanzapine Excipient with known effect: Each orodispersible tablet contains 0.92 mg aspartame For the full list of excipients see section 6.1
Croatian: Pomoćna tvar s poznatim učinkom: Svaka raspadljiva tableta za usta sadrži 0,92 mg aspartama.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/09/592/002
Croatian: 12. BROJEVI ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/09/592/002
English: MARKETING AUTHORISATION NUMBER(S) EU/1/09/592/003
Croatian: 12. BROJEVI ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/09/592/003
English: Packaging Content Package size
Croatian: Put primjene Pakovanje Sastav Veličina pakova nja
English: Dogs and cats
Croatian: Psi i mačke Intravenozna primjena, subkutana primjena
English: Intravenous use, subcutaneous use Vial (glass) 20 ml
Croatian: 20 ml
English: Not applicable
Croatian: Karencija
English: Date of first authorisation: 19 March 2015
Croatian: Datum prvog odobrenja: 19. ožujka 2015.
English: • Tilt your head back and look up at the ceiling.
Croatian: • Nagnite glavu natrag i gledajte u strop.
English: Talk to a doctor if you do not feel better or if you feel worse.
Croatian: Obavezno se obratite liječniku ako se ne osjećate bolje ili ako se osjećate lošije.
English: The difference was not statistically significant (p=0.326).
Croatian: Razlika nije bila statistički značajna (p=0,326).
English: However, no special considerations are needed in these populations.
Croatian: Ipak, nisu potrebne posebne prilagodbe u ovim populacijama.
English: Effects on the immune system
Croatian: Učinci na imunološki sustav
English: Do not put in any more drops until it is time for your next regular dose.
Croatian: Nemojte više ukapavati kapi sve dok nije vrijeme za Vašu sljedeću redovnu dozu.
English: Do not use a double dose to make up for the forgotten dose.
Croatian: Nemojte primijeniti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: Both generalised and localised infections can occur.
Croatian: Mogu se pojaviti i generalizirane i lokalizirane infekcije.
English: Each single-dose container is sufficient to treat both eyes.
Croatian: Svaki jednodozni spremnik dovoljan je za liječenje oba oka.
English: Response to treatment should be reassessed at least every 6 months.
Croatian: Odgovor na liječenje treba ponovno procijeniti najmanje svakih 6 mjeseci.
English: If a dose is missed, treatment should be continued on the next day as normal.
Croatian: Ako se propusti jedna doza, liječenje treba nastaviti sljedeći dan kao što je uobičajeno.
English: • If you use drops in both eyes, repeat the steps for your other eye.
Croatian: • Ako primjenjujete kapi u oba oka, ponovite korake za drugo oko.
English: You should visit your doctor at least every 6 months to assess the effect of IKERVIS.
Croatian: Trebali biste posjetiti svog liječnika barem svakih 6 mjeseci kako bi se procijenilo djelovanje IKERVISA.
English: - if you are taking any medicines containing steroids.
Croatian: - ako uzimate bilo kakve lijekove koji sadrže steroide.
English: If you could become pregnant you must use contraception while using this medicine.
Croatian: Ako biste mogli zatrudnjeti, morate koristiti kontracepciju tijekom primjene ovog lijeka.
English: EU/1/15/990/001 EU/1/15/990/002
Croatian: EU/1/15/990/002
English: • Blink a few times so that the medicine covers your eye.
Croatian: • Trepnite nekoliko puta kao bi lijek prekrio oko.
English: Any unused emulsion should be discarded immediately.
Croatian: Neiskorištena emulzija mora se odmah baciti.
English: 67 patients were enrolled (37.9% of the 177 patients having ended Sansika).
Croatian: Bilo je uključeno 67 bolesnika (37,9% od 177 bolesnika koji su završili ispitivanje SANSIKA).
English: Other medicines and IKERVIS
Croatian: Drugi lijekovi i IKERVIS
English: Milky white emulsion.
Croatian: Mliječno bijela emulzija.
English: Precautions to be taken before administering the medicinal product Patients should be instructed to first wash their hands.
Croatian: Mjere opreza koje je potrebno poduzeti prije primjene lijeka Bolesnike treba uputiti da najprije operu ruke.
English: Follow these instructions carefully and ask your doctor or pharmacist if there is anything you do not understand.
Croatian: Pažljivo slijedite ove upute i pitajte svog liječnika ili ljekarnika ako bilo što ne razumijete.
English: They are ranked according to system organ class and classified according to the following convention: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000), or not known (cannot be estimated from the available data).
Croatian: Prikazane su prema klasifikaciji organskih sustava i učestalosti prema sljedećoj kategorizaciji: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000) ili nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Patients should be advised not to drive or use machines until their vision has cleared.
Croatian: Bolesnicima treba savjetovati da ne upravljaju vozilima ili rade sa strojevima sve dok im se vid ne razbistri.
English: If you forget to use IKERVIS, continue with the next dose as planned.
Croatian: Ako ste zaboravili primijeniti IKERVIS, nastavite sa sljedećom dozom prema planu.
English: IKERVIS is likely to be present in breast milk in very small amounts.
Croatian: IKERVIS će vjerojatno biti prisutan u majčinom mlijeku u vrlo malim količinama.
English: Pre-existing infections may also be aggravated (see section 4.3).
Croatian: Prethodno postojeće infekcije se također mogu pogoršati (vidjeti dio 4.3).
English: IKERVIS should not be used in children and adolescents below 18 years old.
Croatian: Djeca i adolescenti IKERVIS se ne smije primjenjivati u djece i adolescenata mlađih od 18 godina.
English: If this happens, wait until your vision clears before you drive or use machines.
Croatian: Ako se to dogodi, pričekajte da Vam se vid ponovo razbistri prije upravljanja vozilima i rada sa strojevima.
English: Tell your doctor or pharmacist if you are using, have recently used or might use any other medicine.
Croatian: Obavijestite svog liječnika ili ljekarnika ako primjenjujete, nedavno ste primijenili ili biste mogli primijeniti bilo koje druge lijekove.
English: België/Belgique/Belgien
Croatian: België/Belgique/Belgien Santen Oy
English: IKERVIS eye drops should be used at least 15 minutes after any other eye drops are used.
Croatian: IKERVIS kapi za oči treba primijeniti najmanje 15 minuta nakon primjene bilo kojih drugih kapi za oči.
English: What IKERVIS is and what it is used for 2.
Croatian: Što je IKERVIS i za što se koristi 2.
English: The following side effects have been reported:
Croatian: Zabilježene su sljedeće nuspojave:
English: If overdose with IKERVIS occurs, treatment should be symptomatic and supportive.
Croatian: U slučaju predoziranja IKERVISOM, liječenje treba biti simptomatsko i suportivno.
English: IKERVIS is not recommended during pregnancy unless the potential benefit to the mother outweighs the potential risk to the foetus.
Croatian: Ne preporučuje se koristiti lijek IKERVIS tijekom trudnoće ukoliko moguća korist za majku ne nadmašuje mogući rizik za fetus.
English: What IKERVIS is and what it is used for
Croatian: Što je IKERVIS i za što se koristi
English: - if you are taking any medicines to treat glaucoma.
Croatian: - ako uzimate bilo kakve lijekove za liječenje glaukoma.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from IKERVIS therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Croatian: Potrebno je odlučiti da li prekinuti dojenje ili prekinuti liječenje/suzdržati se od liječenja lijekom IKERVIS uzimajući u obzir korist dojenja za dijete i korist liječenja za ženu.
English: This helps to stop IKERVIS getting into the rest of the body.
Croatian: To pomaže u smanjenju ulaska IKERVISA u ostatak tijela.
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, phototoxicity and photoallergy, genotoxicity, carcinogenic potential, toxicity to reproduction and development.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, fototoksičnosti i preosjetljivosti na svjetlost, genotoksičnosti, kancerogenog potencijala, reproduktivne i razvojne toksičnosti.
English: • Discard the single dose container as soon as you have used it, even if there is still some liquid left in it.
Croatian: • Jednodozni spremnik bacite odmah nakon primjene, čak i ako je ostalo nešto tekućine u njemu.
English: After 12 months of treatment, values were below the low limit of detection for 56 patients and below the low limit of quantification in 19 patients.
Croatian: Nakon 12 mjeseci liječenja vrijednosti su bile ispod donje granice detekcije u 56 bolesnika i ispod donje granice kvantifikacije u 19 bolesnika.
English: Careful monitoring of patients with severe keratitis is recommended.
Croatian: Preporučuje se pažljiv nadzor bolesnika s teškim keratitisom.
English: Contact lenses can further damage the transparent front part of the eye (cornea).
Croatian: Kontaktne leće mogu još više oštetiti prozirni prednji dio oka (rožnicu).
English: However, at therapeutic doses of ciclosporin in eye drops, it is unlikely that sufficient amounts would be present in breast milk.
Croatian: Međutim, pri terapijskim dozama ciklosporina u kapima za oko nije vjerojatno da će u majčinom mlijeku biti prisutna dostatna količina.
English: Caution should be exercised when treating these patients concomitantly with IKERVIS, especially with beta-blockers which are known to decrease tear secretion.
Croatian: Potreban je oprez pri liječenju tih bolesnika istodobno s IKERVISOM, posebno uz beta blokatore za koje je poznato da smanjuju izlučivanje suza.
English: This study was designed to monitor the long-term efficacy and relapse rates in patients who have previously received IKERVIS.
Croatian: Ovo ispitivanje osmišljeno je za praćenje dugoročne djelotvornosti i stope relapsa u bolesnika koji su prethodno liječeni IKERVISOM.
English: At completion of the SANSIKA study (12 month study), patients were asked to enter the Post SANSIKA study.
Croatian: Po završetku ispitivanja SANSIKA (ispitivanje je trajalo 12 mjeseci), bolesnici su zamoljeni da sudjeluju u ispitivanju Post SANSIKA.
English: After the 24-month period, 61.3% of 62 patients included in the primary efficacy population did not experience a relapse based on CFS scores.
Croatian: Nakon razdoblja od 24 mjeseca u 61,3% od 62 bolesnika uključena u populaciju u kojoj je procijenjena primarna djelotvornost nije došlo do relapsa temeljeno na bodovima CFS-a.
English: To reduce the systemic absorption, see section 4.2.
Croatian: Za smanjenje sustavne apsorpcije, vidjeti dio 4.2.
English: Ciclosporin belongs to a group of medicines known as immunosuppressive agents that are used to reduce inflammation.
Croatian: Ciklosporin pripada skupini lijekova poznatih kao imunosupresivne tvari koje se koriste za smanjenje upale.
English: In both studies one third of the patients in average had Sjögren's syndrome; as for the overall population, a statistically significant improvement in CFS in favour of IKERVIS was observed in this subgroup of patients.
Croatian: U oba ispitivanja prosječno je jedna trećina bolesnika imala Sjögrenov sindrom; kao i u ukupnoj populaciji, u ovoj podskupini bolesnika uočeno je signifikantno poboljšanje nalaza CFS-a u korist IKERVISA.
English: If you use more IKERVIS than you should, rinse your eye with water.
Croatian: Ako primijenite više IKERVISA nego što ste trebali, isperite oko vodom.
English: • Pull down your lower eyelid (picture 2).
Croatian: • Povucite svoju donju vjeđu prema dolje (slika 2).
English: Patients wearing contact lenses have not been studied.
Croatian: Primjena u bolesnika koji nose kontaktne leće nije ispitana.
English: • Twist off the cap (picture 1).
Croatian: • Odvijte čep (slika 1).
English: The most common side effects are in and around the eyes.
Croatian: Najčešće nuspojave bile su na očima ili oko njih.
English: Seven patients had measurable values (from 0.105 to 1.27 ng/mL), all considered to be negligible values.
Croatian: Sedam bolesnika imalo je mjerljive vrijednosti (od 0,105 do 1,27 ng/ml) koje su sve smatrane zanemarivima.
English: Patients should be instructed to use nasolacrimal occlusion and to close the eyelids for 2 minutes after instillation, to reduce the systemic absorption.
Croatian: Bolesnike treba uputiti da provode nazolakrimalnu okluziju i da zatvore vjeđe na 2 minute nakon ukapavanja kako bi smanjili sustavnu apsorpciju.
English: The median global VAS score increased from the time treatment was first stopped (23.3%) to the time treatment was restarted (45.1%).
Croatian: Medijan ukupnog rezultata dobivenog vizualno-analognom skalom porastao je u razdoblju od prvog prekida liječenja (23,3%) do ponovnog uvođenja liječenja (45,1%).
English: Uncommon side effects related to the eye:
Croatian: Manje česte nuspojave povezane s okom:
English: Ciclosporin appears to block the resting lymphocytes in the G0 or G1 phase of the cell cycle.
Croatian: Čini se da ciklosporin blokira limfocite u mirovanju u G0 ili G1 fazi staničnog ciklusa.
English: It is also known to up-regulate the release of anti-inflammatory cytokines.
Croatian: Također je poznato da povećava otpuštanje protuupalnih citokina.
English: All available evidence suggests that ciclosporin acts specifically and reversibly on lymphocytes and does not depress haematopoiesis or has any effect on the function of phagocytic cells..
Croatian: Svi dostupni podaci pokazuju da ciklosporin djeluje specifično i reverzibilno na limfocite te da ne potiskuje hematopoezu i nema nikakav učinak na funkciju fagocita.
English: Do not use more than one drop each day in the affected eye(s).
Croatian: Nemojte primijeniti više od jedne kapi u zahvaćeno oko (oči) na dan.
English: The recommended dose is one drop in each affected eye, once daily at bedtime.
Croatian: Preporučena doza je jedna kap u svako zahvaćeno oko, jednom dnevno, prije spavanja.
English: Studies in animals suggest that ciclosporin inhibits the development of cell-mediated reactions.
Croatian: Ispitivanja na životinjama pokazuju da ciklosporin inhibira razvoj stanično posredovanih reakcija.