FrancophonIA/ELRC3.0 huggingface dataset:
English: Potent inducers of CYP3A (e.g., rifampicin, phenobarbital and carbamazepine) reduce nelfinavir plasma concentrations.
Maltese: Indutturi qawwija ta' CYP3A (e.ż., rifampicin, phenobarbital u carbamazepine) inaqqsu lkonċentrazzjonijiet fil-plażma ta' nelfinavir.
English: Nelfinavir reversibly binds to the active site of HIV protease and prevents cleavage of the polyproteins resulting in the formation of immature non-infectious viral particles.
Maltese: Nelfinavir jingħaqad b'mod reversibbli mal-partijiet attivi talprotease ta' l-HIV u jevita l-qtugħ tal-molekuli tal-poliproteini, u jirriżulta fil-formazzjoni ta' partiċelli virali immaturi u mhux infettivi.
English: During these trials less than 13% of patients in total discontinued treatment due to adverse events.
Maltese: Waqt dawn il-provi inqas minn total ta' 13 % tal-pazjenti waqqfu l-kura minħabba avvenimenti avversi.
English: Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltese insufficiency should not take this medicine.
Maltese: Pazjenti b'problemi ereditarji rari ta' intolleranza għal fructose, assorbiment ħażin ta' glucose-galactose jew insuffiċjenza ta' sucrase-isomaltese m'għandhomx jieħdu din il-mediċina.
English: A pharmacokinetic study in HIV-positive patients compared multiple doses of 1250 mg twice daily (BID) with multiple doses of 750 mg three times daily (TID) for 28 days.
Maltese: Studju farmakokinetiku f'pazjenti pożittivi għal HIV ipparaguna dożi multipli ta' 1250 mg mogħtija darbtejn kuljum (BID) ma' dożi multipli ta' 750 mg mogħtija tliet kuljum (TID) għal 28 jum.
English: Patients older than 13 years: VIRACEPT 250 mg tablets are recommended for adults and older children (see Summary of Product Characteristics for VIRACEPT 250 mg tablets).
Maltese: Il-pilloli VIRACEPT ta' 250 mg huma rrakkomandati għal adulti u tfal kbar (ara s-Sommarju tal-Karatteristiċi tal-Prodott għall-pilloli ta' VIRACEPT ta' 250 mg).
English: Dosing Regimen1 N2
Maltese: 2-9 xhur
English: Serious and non-serious adverse reactions from post-marketing spontaneous reports (where nelfinavir was taken as the sole protease inhibitor or in combination with other antiretroviral therapy), not mentioned previously in section 4.8, for which a causal relationship to nelfinavir cannot be excluded, are summarised below.
Maltese: Reazzjonijiet avversi serji u mhux serji minn rapporti spontanji ta' wara t-tqegħid fis-suq (fejn nelfinavir ittieħed bħala l-uniku inibitur ta' protease jew flimkien ma' terapija antiretrovirali oħra), mhux imsemmija qabel f'sezzjoni 4.8, li għalihom relazzjoni kawżali għal nelfinavir ma tistax tiġi eskluża, huma miġbura isfel.
English: MARKETING AUTHORISATION NUMBER(S) EU/01/097/054/004
Maltese: FIS-SUQ EU/01/097/054/004
English: The mean decrease in plasma HIV RNA using a PCR assay (< 400 copies/ml) at 24 weeks was 2.33 log10 in patients receiving combination therapy with nelfinavir 750 mg TID, compared to 1.34 log10 in patients receiving zidovudine and lamivudine alone.
Maltese: f'pazjenti li kienu qed jirċievu t-terapija mħallta ma' 750 mg ta' nelfinavir TID, meta mqabbel ma' 1.34 log10 f'pazjenti li kienu qed jirċievu zidovudine u lamivudine waħdu.
English: Viracept tablets are generally recommended for adults and older children.
Maltese: Pilloli Viracept ġeneralment huma rrakkomandati għall-adulti u tfal akbar.
English: Co-administration with medicinal products with narrow therapeutic windows and which are substrates of CYP3A4 [e.g., terfenadine, astemizole, cisapride, amiodarone, quinidine, pimozide, triazolam, orally administered midazolam (for caution on parenterally administered midazolam, see section 4.5), ergot derivatives, lovastatin and simvastatin, alfuzosin, and sildenafil when used for treatment of pulmonary arterial hypertension hypertension (for the use of sildenafil and other PDE-5 inhibitors in patients with erectile dysfunction, see section 4.5)].
Maltese: L-għoti flimkien ma' prodotti mediċinali oħra li għandhom indiċi terapewtiku żgħir u li huma sottostrati ta' CYP3A4 [eż. terfenadine, astemizole, cisapride, amiodarone, quinidine, pimozide,triazolam, midazolam li jingħata mill-ħalq (għal attenzjoni dwar midazolam mogħti b'mod parenterali, ara sezzjoni 4.5), derivattivi ta' ergot, lovastatin u simvastatin, alfuzosin, u sildenafil meta jintuża għall-kura ta' pressjoni pulmonari arterjali għolja (għall-użu ta' sildenafil u ta' inibituri oħra ta' PDE-5 f'pazjenti b'disfunzjoni erettili, ara sezzjoni 4.5)].
English: For other substrates of CYP3A4 a dose reduction or consideration of an alternative may be required (Table 1).
Maltese: Għal substrati oħra ta' CYP3A4 jista' jkun meħtieġ tnaqqis fid-doża jew kunsiderazzjoni ta' alternattiva (Tabella 1).
English: Each film-coated tablet contains 250 mg of nelfinavir (as mesilate).
Maltese: Kull pillola miksija b'rita fiha 250 mg ta' nelfinavir (bħala mesilate).
English: The pharmacokinetics of nelfinavir are similar during BID and TID administration.
Maltese: Il-farmakokinetika ta' nelfinavir huma simili waqt l-għoti BID u l-għoti TID.
English: The safety of the VIRACEPT 250 mg tablet was studied in controlled clinical trials with over 1300 patients.
Maltese: Is-sigurtà tal-pillola VIRACEPT 250 mg kienet studjata fi provi kliniċi kkontrollati b'aktar minn 1300 pazjent.
English: Combination antiretroviral therapy has been associated with metabolic abnormalities such asblood triglycerides increased, blood cholesterol increased, insulin resistance, hyperglycaemia and hyperlactaemia.
Maltese: Terapija antiretrovirali kombinata ġiet assoċjata ma' anormalitajiet metaboliċi bħal żjieda tattrigliċeridi fid-demm, żjieda tal-kolesterol fid-demm, reżistenza għall-insulina, ipergliċemija u iperlaktimja.
English: White Scoop (1 g)
Maltese: (bħala grammi) 8 g
English: The cleavage of these viral polyproteins is essential for the maturation of infectious virus.
Maltese: Il-qtugħ ta' dawn il-poliproteini virali huwa essenzjali għall-maturazzjoni tal-vajrus infettiv.
English: See section 2 and 6.1 for further information on excipients.
Maltese: Ara sezzjoni 2 u 6.1 għal aktar informazzjoni dwar is-sustanzi mhux attivi.
English: In a study of 297 HIV-1 seropositive patients receiving zidovudine and lamivudine plus nelfinavir (2 different doses) or zidovudine and lamivudine alone, the mean baseline CD4 cell count was 288 cells/mm3 and the mean baseline plasma HIV RNA was 5.21 log10 copies/ml (160,394 copies/ml).
Maltese: Fi studju ta' 297 f'pazjenti seropożittivi għall-HIV-1 li kienu qed jirċievu zidovudine u lamivudine flimkien ma' nelfinavir (2 dożi differenti) jew zidovudine u lamivudine waħidhom, il-medja tal-linja bażi ta' l-għadd taċ-ċelluli CD4 kienet ta' 288 ċelluli/mm3, u l-medja tal-linja bażi tal-plażma ta' lRNA ta' l-HIV kienet ta' 5.21 log10 kopji/ml.
English: This may lead to a loss of virologic response and possible resistance to VIRACEPT (see section 4.5).
Maltese: Dan jista' jwassal għal telf tarrispons viroloġiku u l- possibbiltà ta' reżistenza għal VIRACEPT (ara sezzjoni 4.5).
English: hyperlipaemia (increased fats in the blood) and resistance to insulin.
Maltese: Reżistenza inkroċjata (cross resistance) in vitro:
English: Chronic nelfinavir treatment of rats has been demonstrated to produce effects consistent with enzyme induction, which predisposed rats, but not humans, to thyroid neoplasms.
Maltese: It-trattament kroniku b'nelfinavir tal-firien kien muri li jipproduċi effetti konsistenti ma' l-induzzjoni ta' enzimi, li ppredispona l-firien, imma mhux il-bnedmin, għan-neoplażmi tat-tirojde.
English: • Wind.
Maltese: • Gass.
English: Since increased concentrations of HMG-CoA reductase inhibitors may cause myopathy, including rhabdomyolysis, the combination of these medicinal products with nelfinavir is not recommended.
Maltese: Peress li żjieda filkonċentrazzjonijiet ta' inibituri ta' HMG-CoA reductase tista' tikkawża mijopatija, inkluż rabdomijolisi, it-taħlita ta' dawn il-prodotti mediċinali ma' nelfinavir mhijiex irrakkomandata.
English: If you want to take the powder instead please see the Package Leaflet for Viracept 50 mg/g oral powder.
Maltese: B'mod alternattiv, jista' jintuża Viracept 50 mg/g trab orali.
English: Roche Pharma AG Emil-Barell-Strasse 1 D-79639 Grenzach-Whylen Germany
Maltese: D-79639 Grenzach-Whylen Il-Ġermanja
English: HOW TO TAKE VIRACEPT
Maltese: X'fih Viracept
English: Herbal preparations containing St. John's wort (Hypericum perforatum) must not be used while taking nelfinavir due to the risk of decreased plasma concentrations and reduced clinical effects of nelfinavir (see section 4.5).
Maltese: John's wort [Hypericum perforatum] m'għandhomx jintużaw meta nelfinavir ikun qed jittieħed minħabba r-riskju ta' konċentrazzjonijiet tal-plażma mnaqqsa u effetti kliniċi mnaqqsa ta'nelfinavir (ara sezzjoni 4.5).
English: Only 1-2 % of the dose was recovered in urine, of which unchanged nelfinavir was the major component.
Maltese: 1-2 % biss tad-doża kienet irkuprata fl-awrina, li minnha nelfinavir mhux mibdul kien il-komponent ewlieni.
English: Plasma levels of certain HIV-1 protease inhibitors, which are metabolised predominantly by CYP3A4, can be increased by the co-administration of low-dose ritonavir, which is an inhibitor of this metabolism.
Maltese: Livelli fil-plażma ta' ċertu tipi ta' inibituri ta' HIV-1 protease, li huma mmetabolizzati primarjament minn CYP3A4, jistgħu jiżdiedu bl-għoti flimkien ta' doża baxxa ta' ritonavir, li huwa inibitur ta' dan il-metaboliżmu.
English: Each gram of oral powder contains 50 mg of nelfinavir (as mesilate).
Maltese: Kull gramma ta' trab orali fiha 50 mg ta' nelfinavir (bħala mesilate).
English: The mean increase from baseline in CD4+ cell count at week 48 was 195 cells/mm3 and 207 cells/mm3 in the nelfinavir and lopinavir/ritonavir groups respectively.
Maltese: Iż-żjieda medja mill-linja bażi ta' lgħadd taċ-ċelluli CD4+ fit-48 ġimgħa kienet ta' 195 ċellula/mm3 u 207 ċellula/mm3 fil-gruppi b'nelfinavir u b'lopinavir/ritonavir rispettivament.
English: The pharmacokinetic properties of nelfinavir have been evaluated in healthy volunteers and HIV-infected patients.
Maltese: Il-proprjetajiet farmakokinetiċi ta' nelfinavir kienu evalwati f'voluntiera f'saħħithom u f'pazjenti infettati bl-HIV.
English: A randomised open-label study compared the HIV RNA suppression of nelfinavir 1250 mg BID versus nelfinavir 750 mg TID in PI naïve patients also receiving stavudine (30-40 mg BID) and lamivudine (150 mg BID).
Maltese: Studju fejn l-investigatur u s-suġġett kienu jafu xi trattament kien qed jingħata, magħżul bl-addoċċ, ipparaguna s-sopressjoni ta' RNA ta' HIV ta' 1250 mg ta' nelfinavir BID kontra 750 mg ta' nelfinavir TID f'pazjenti mhux affettwati minn PIs li kienu qed jirċievu wkoll stavudine (30-40 mg BID) u lamivudine (150 mg BID).
English: In vitro: HIV isolates with reduced susceptibility to nelfinavir have been selected in vitro.
Maltese: Iżolati ta' HIV b'suxxettibbilità mnaqqsa għal nelfinavir kienu magħżula in vitro.
English: Each bottle contains 144 grams of oral powder and is supplied with a 1 gram (white) and a 5 gram (blue) polypropylene scoop.
Maltese: Kull flixkun fih 144 gramma ta' trab orali u huwa pprovdut ma' kuċċarina tal-polypropylene ta' gramma (bajda) u ta' 5 grammi (kaħla).
English: Consider alternatives to fluticasone propionate, that are not metabolised by CYP3A4, such as beclometasone, particularly for long-term use.
Maltese: Ikkunsidra alternattivi għal fluticasone propionate li mhux metabolizzati minn CYP3A4, bħal beclometasone, speċjalment għall-użu fit-tul.
English: Osteonecrosis: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to combination antiretroviral therapy (CART).
Maltese: Għalkemm l-etjoloġija hija kkunsidrata li ġejja minn ħafna fatturi (inkluż l-użu ta' kortikosterojdi, konsum ta' alkoħol, immunosoppressjoni severa, indiċi tal-massa tal-ġisem għola), każijiet ta' osteonekrożi ġew irrappurtati partikolarment f'pazjenti b'marda ta' l-HIV avvanzata u/jew esponiment fit-tul għal terapija antiretrovirali kombinata (CART).
English: Store in the original container.
Maltese: Aħżen fil-pakkett oriġinali.
English: Magnesium stearate,
Maltese: Mhux applikabbli.
English: amprenavir, efavirenz or nevirapine
Maltese: Is-sinjali jistgħu jinkludu diffikultà biex tieħu n-nifs,
English: Immune Reactivation Syndrome: In HIV-infected patients with severe immune deficiency at the time of institution of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic pathogens may arise and cause serious clinical conditions, or aggravation of symptoms.
Maltese: Sindromu tar-Riattivazzjoni Immuni: F'pazjenti nfetti b'HIV b'defiċjenza immuni severa fil-ħin li tinbeda t-terapija antiretrovirali kombinata (CART), tista' sseħħ reazzjoni inflammatorja għallpatoġeni mingħajr sintomi jew patoġeni residwali, opportunistiċi li tista' tikkawża kondizzjonijiet kliniċi serji, jew aggravar tas-sintomi.
English: The bottle contains 144 g of oral powder.
Maltese: Il-flixkun fih 144 g ta' trab orali.
English: The efficacy of the BID regimen has been evaluated versus the TID regimen with VIRACEPT 250 mg tablets primarily in patients naïve to PIs.
Maltese: L-effikaċja tal-kors BID kien evalwat kontra l-kors TID b'pilloli VIRACEPT 250 mg primarjament f'pazjenti ġodda għal PIs.
English: If nelfinavir is co-administered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Maltese: Jekk nelfinavir jingħata flimkien ma' midazolam parenterali, dan għandu jsir f'taqsima ta' kura intensiva (ICU) jew post simili li jassigura sorveljanza klinika millviċin u mmaniġġjar mediku xieraq f'każ ta' depressjoni respiratorja u/jew sedazzjoni mtawwla.
English: There are two scoops provided in the box, a white 1 gram scoop and a blue 5 gram scoop.
Maltese: Hemm żewġ kuċċarini pprovduti fil-kaxxa, kuċċarina bajda ta' ġramma waħda u kuċċarina blu ta' 5 grammi.
English: 270 film-coated tablets
Maltese: Kull flixkun fih 270 jew 300 pillola.
English: • Simvastatin or lovastatin (for lowering blood cholesterol)
Maltese: • Simvastatin jew lovastatin (biex inaqqsu l-kolesterol fid-demm)
English: Substrates for CYP3A4: Co-administration is contraindicated with the following agents that are substrates for CYP3A4 and that have narrow therapeutic windows: terfenadine, astemizole, cisapride, amiodarone, quinidine, ergot derivatives, pimozide, oral midazolam, triazolam, alfuzosin, and sildenafil when used to treat pulmonary arterial hypertension (see section 4.3).
Maltese: L-għoti flimkien mas-sustanzi li ġejjin li huma sottostrati ta' CYP3A4 u li għandhom raġġ terapewtiku żgħir huwa kontra-indikat: terfenadine, astemizole, cisapride, amiodarone, quinidine, derivattivi ta' ergot, pimozide, midazolam orali, triazolam, alfuzosin, u sildenafil meta jintuża għall-kura ta' pressjoni pulmonari arterjali għoja (ara sezzjoni 4.3).
English: 8 g 10 g 11 g 13 g 15 g
Maltese: 13 g 15 g
English: The combination may result in increased risk of cardiovascular adverse events associated with salmeterol, including QT prolongation, palpitations and sinus tachycardia.
Maltese: It-taħlita tista' twassal għal riskju akbar ta' avvenimenti kardjovaskulari avversi assoċjati ma' salmeterol, inkluż titwil ta' QT, palpitazzjonijiet u takikardija sinus.
English: Atorvastatin AUC ↑ 74 % Nelfinavir AUC concentrations not measured
Maltese: AUC ta' nelfinavir ↑ 20 % AUC tal-metabolit M8 ↑ 74 %
English: Each gram of oral powder contains nelfinavir mesilate corresponding to 50 mg of nelfinavir.
Maltese: Kull gramma ta' trab orali fiha nelfinavir mesilate li jikkorrispondi għal 50 mg ta' nelfinavir.
English: One major and several minor oxidative metabolites were found in plasma.
Maltese: Fil-plażma instabu metabolit ossidattiv maġġuri wieħed u bosta minuri.
English: Each dose contains up to 5.9 milligrams of sucrose, which should be taken into account in patients with diabetes mellitus.
Maltese: Kull doża fiha sa 5.9 milligrammi ta' sucrose, li għandu jittieħed f'kunsiderazzjoni f'pazjenti b'dijabete mellitus.
English: In vivo: The overall incidence of the D30N mutation in the viral protease of assessable isolates (n=157) from patients receiving nelfinavir monotherapy or nelfinavir in combination with zidovudine and lamivudine or stavudine was 54.8 %.
Maltese: L-inċidenza totali tal-mutazzjoni D30N fil-protease virali ta' iżolati li setgħu jkunu assessjati (n=157) minn pazjenti li kienu qed jirċievu monoterapija ta' nelfinavir jew nelfinavir flimkien ma' zidovudine u lamivudine jew stavudine kienet ta' 54.8 %.
English: 10.5 to 12 kg*
Maltese: 10.5 sa 12 kg flimkien ma'
English: Hepatobiliary disorders:
Maltese: Indutturi ta' l-enżimi metaboliċi:
English: • Table 2: if you give the medicine two times a day, you will give 50-55 mg nelfinavir each time for each kg of body weight.
Maltese: • Tabella 2: jekk tagħti l-mediċina darbtejn kuljum, inti ser tagħti 50-55 mg nelfinavir għal kull kg ta' piz tal-ġisem kull darba.
English: Administration of 300 mg/kg/day resulted in an increased incidence of thyroid follicular cell adenoma.
Maltese: L-għoti ta' 1000 mg/kg/kuljum irriżulta f'żjieda fl-inċidenza ta' adenoma taċ-ċelluli follikulari fit-tirojde.
English: in both groups.
Maltese: Eritema multiforme.
English: Dosage reduction of rifabutin to 150 mg QD is necessary when nelfinavir 750 mg TID or 1250 mg BID and rifabutin are co-administered.
Maltese: Tnaqqis fid-dożaġġ ta' rifabutin għal 150 mg QD huwa neċessarju meta nelfinavir 750 mg TID jew 1250 mg BID u rifabutin jingħataw flimkien.
English: The estimated volumes of distribution in both animals and humans is 2-7 l/kg which exceeded total body water and suggests extensive penetration of nelfinavir into tissues.
Maltese: Il-volum ta' distribuzzjoni stmat fil-bhejjem u l-bnedmin huwa ta' 2-7 l/kg li huwa aktar mill-ilma totali tal-ġisem u jissuġġerixxi penetrazzjoni estensiva ta' nelfinavir fit-tessuti.
English: • Medicines made from ergot such as cabergoline, ergotamine or lisuride (for Parkinson's disease or migraine)
Maltese: • Mediċini magħmula minn ergot bħal cabergoline, ergotamine jew lisuride (għall-marda ta'
English: • Viracept can stop oral contraceptives (the pill) from working, so you should use other contraception methods (such as condoms) while you are taking Viracept.
Maltese: • Viracept jista' jwaqqaf il-konraċettivi orali (il-pillola kontraċettiva) milli jaħdmu, għalhekk għandek tuża metodi kontraċettivi oħra (bħal kondoms) waqt li qed tieħu Viracept.
English: Parenteral midazolam should be coadministered with nelfinavir in an intensive care unit to ensure close clinical monitoring.
Maltese: Midazolam parenterali għandu jingħata flimkien ma' nelfinavir f'unità ta' kura intensiva biex tiġi żgurata sorveljanaza klinika mill-viċin.
English: Viracept contains a medicine called nelfinavir, which is a ‘protease inhibitor'.
Maltese: Viracept fih mediċina msejħa nelfinavir, li hija ‘inibitur tal-protease'.
English: These children will be given a different number of tablets with each meal.
Maltese: Dawn it-tfal se jingħataw numru differenti ta' pilloli ma' kull ikla.
English: Excipients: - Contains sucrose palmitate: 10.0 mg per gram of oral powder.
Maltese: - sucrose palmitate - benna naturali u artifiċjali.
English: This may
Maltese: ‘Logo'
English: If you have haemophilia type A or B, in rare
Maltese: Din fuljett kien approvat l-aħħar fit
English: See section 5.1.
Maltese: J05A E04.
English: Mutagenicity: in vitro and in vivo studies with and without metabolic activation have shown that nelfinavir has no mutagenic or genotoxic activity.
Maltese: Studji in vitro u in vivo bi u mingħajr l-attivazzjoni metabolika wrew li nelfinavir m'għandu l-ebda attività mutaġenika jew ġenotossika.
English: • You have a rare blood problem which runs in families called ‘haemophilia'.
Maltese: • Għandek problema rari tad-demm li tintiret imsejjħa ‘emofilja'.
English: The multi-dose pharmacokinetics of nelfinavir have not been studied in HIV-positive patients with hepatic insufficiency.
Maltese: Il-farmakokinetika ta' ħafna dożi ta' nelfinavir ma ġietx studjata f'pazjenti pożittivi għal HIV b'insuffiċjenza tal-fwied.
English: 8 g 10 g 12 g 14 g 16 g 18 g 21 g over 22 kg
Maltese: 12 sa 14-il kg* 14 sa 16-il kg 16 sa 18-il kg 18 sa 22 kg*
English: Uncommon (affect less than 1 in 100 people):
Maltese: Mhux komuni (jaffettwaw inqas minn persuna waħda minn kull 100):
English: Limited clinical trial data from patients receiving one or more of these medicinal products with nelfinavir indicated that a clinically significant effect on safety and efficacy is not expected.
Maltese: Tagħrif limitat minn provi kliniċi minn pazjenti li qed jirċievu wieħed jew aktar minn dawn il-prodotti mediċinali ma' nelfinavir indika li mhux mistenni effett sinifikanti fuq is-sigurtà u l-effikaċja.
English: over 22 kg * Children with these weights will be given an uneven number of tablets during the day.
Maltese: 22 kg * Tfal b'dawn il-piżijiet se jingħataw numru disparu ta' pilloli matul ilġurnata.
English: White Scoop
Maltese: L-KITBA
English: Concomitant use of fluticasone propionate and VIRACEPT may increase plasma concentrations of fluticasone propionate.
Maltese: L-użu ta' fluticasone propionate u VIRACEPT fl-istess waqt jista' jżid il-konċentrazzjonijiet ta' fluticasone propionate fil-plażma.
English: • Sildenafil (for getting or keeping an erection)
Maltese: • Sildenafil (biex tikseb jew iżżomm erezzjoni)
English: In some patients with advanced HIV infection and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Maltese: F'xi pazjenti b'infezzjoni avanzata ta' l-HIV u b'passat ta' infezzjoni opportunistika, jistgħu jseħħu sinjali u sintomi ta' infjammazjoni minn infezzjonijiet ta' qabel ftit wara li tinbeda kura kontra l-HIV.
English: Combination of simvastatin or lovastatin and nelfinavir is contraindicated (see contraindication).
Maltese: Taħlita ta' simvastatin jew lovastatin u nelfinavir mhijiex irrakkomandata (ara kontraindikazzjoni).
English: Body fat
Maltese: Kull Grad
English: • Atorvastatin or other statins (for lowering blood cholesterol)
Maltese: • Atorvastatin jew statins oħra (biex inaqqsu l-kolesterol fid-demm)
English: Blue, oblong biconvex film-coated tablets.
Maltese: Pilloli blu, oblung, ibbuzzati fuq iż-żewġ naħat, miksija b'rita.
English: Administration of VIRACEPT oral powder or tablets at a dose of approximately 25-30 mg/kg TID with food achieves steady-state plasma concentrations that are similar to those achieved in adult patients receiving 750 mg TID.
Maltese: L-għoti ta' trab ta' VIRACEPT li jittieħed mill-ħalq jew ta' pilloli f'doża ta' madwar 25-30 mg/kg TID ma' l-ikel jikseb konċentrazzjonijiet fissi fil-plażma li huma simili għal dawk li ntlaħqu f'pazjenti adulti li kienu qed jirċievu 750 mg TID.
English: Combination with other medicinal products: Caution is advised whenever VIRACEPT is coadministered with agents that are inducers or inhibitors and/or substrates of CYP3A4; such combinations may require dose adjustment (see also sections 4.3 and 4.8).
Maltese: Taħlita ma' prodotti mediċinali oħra: Attenzjoni hija rrakkomandata kull meta VIRACEPT jingħata flimkien ma' sustanzi li huma indutturi jew inibituri u/jew substrati ta' CYP3A4; taħlitiet bħal dawn jistgħu jeħtieġu aġġustament tad-doża (ara wkoll sezzjonijiet 4.3 u 4.8).
English: • Tadalafil (for pulmonary arterial hypertension (PAH), or for getting or keeping an erection)
Maltese: • Tadalafil (għall-pressjoni pulmonari arterjali għolja (PAH), jew biex ikollok jew iżżomm