FrancophonIA/ELRC3.0 huggingface dataset:
English: • The other ingredients are microcrystalline cellulose, mannitol, povidone, crospovidone and magnesium stearate within the tablet core.
Slovenian: • Druge sestavine zdravila so mikrokristalna celuloza, manitol, povidon, krospovidon in magnezijev stearat v jedru tablete.
English: What Sivextro looks like and contents of the pack Sivextro is an oval, yellow film-coated tablet imprinted with ‘TZD' on one side and ‘200' on the other side.
Slovenian: Izgled zdravila Sivextro in vsebina pakiranja Zdravilo Sivextro je v obliki ovalnih, rumenih filmsko obloženih tablet z vtisnjenima oznakama "TZD" na eni in "200" na drugi strani.
English: imipramine, isocarboxazid, lofepramine, moclobemide, paroxetine, phenelzine, selegiline and sertraline (used to treat depression)
Slovenian: izokarboksazid, lofepramin, moklobemid, paroksetin, fenelzin, selegilin in sertralin (za zdravljenje depresije)
English: Only limited data are available on the compatibility of Sivextro with other intravenous substances, therefore additives or other medicinal products should not be added to Sivextro single use vials or infused simultaneously.
Slovenian: Ker je podatkov o kompatibilnosti zdravila Sivextro z drugimi intravenskimi učinkovinami malo, se vialam zdravila Sivextro za enkratno uporabo ne sme dodati aditivov ali drugih zdravil in se jih ne sme infundirati sočasno.
English: The time to tedizolid peak concentration with oral administration under fasting conditions is 6 hours faster than when administered with a high-fat, high-calorie meal (see section 5.2).
Slovenian: Čas do najvišje koncentracije tedizolida pri peroralni uporabi na tešče je za 6 ur krajši kot pri zaužitju z visokokaloričnim obrokom z visoko vsebnostjo maščob (glejte poglavje 5.2).
English: In an animal model of infection, the antibacterial activity of tedizolid was reduced in the absence of granulocytes.
Slovenian: Pri živalskem modelu okužbe se je protibakterijsko delovanje tedizolida v odsotnosti granulocitov zmanjšalo.
English: There are no data from the use of tedizolid phosphate in pregnant women.
Slovenian: Podatkov o uporabi tedizolid fosfata pri nosečnicah ni.
English: Haemodialysis does not result in meaningful removal of tedizolid from systemic circulation.
Slovenian: Hemodializa ne odstrani pomembne količine tedizolida iz sistemskega obtoka.
English: You should take all 6 tablets to complete your course of treatment, even if you have missed a dose.
Slovenian: Tudi če ste izpustili odmerek, morate vzeti vseh 6 tablet, da dokončate zdravljenje.
English: Multiple sulfotransferase (SULT) isoforms (SULT1A1, SULT1A2, and SULT2A1) were identified in vitro that are capable of conjugating tedizolid which suggests that no single isozyme is critical to the clearance of tedizolid.
Slovenian: In vitro so opredelili več izooblik sulfotransferaze (SULT) (SULT1A1, SULT1A2 in SULT2A1), ki so sposobne konjugacije tedizolida, kar nakazuje, da za očistek tedizolida ni ključen noben posamezen izoencim.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or nurse for advice before using this medicine.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom ali medicinsko sestro, preden prejmete to zdravilo.
English: Insomnia Sleep disorder Anxiety Nightmare
Slovenian: Psihiatrične motnje nespečnost motnje spanja anksioznost nočne more
English: Effects of Sivextro on other medicines
Slovenian: Vplivi zdravila Sivextro na druga zdravila
English: The most frequently reported adverse reactions occurring in patients receiving tedizolid phosphate in the pooled controlled Phase 3 clinical studies (tedizolid phosphate 200 mg once daily for 6 days) were nausea (6.9%), headache (3.5%), diarrhoea (3.2%) and vomiting (2.3%), and were generally mild to moderate in severity.
Slovenian: Najpogosteje poročani neželeni učinki v združenih nadzorovanih kliničnih študijah 3. faze pri bolnikih, ki so prejemali tedizolid fosfat (200 mg tedizolid fosfata enkrat dnevno 6 dni), so bili navzea (6,9 %), glavobol (3,5 %), diareja (3,2 %) in bruhanje (2,3%) ter so bili večinoma blagi do zmerni.
English: It is unknown whether tedizolid phosphate or its metabolites are excreted in human milk.
Slovenian: Ni znano, ali se tedizolid fosfat in njegovi presnovki izločajo v materino mleko.
English: , Mg including Lactated Ringer's Injection and Hartmann's Solution.
Slovenian: , Mg vključno z raztopino Ringerjevega laktata za injiciranje in Hartmannovo raztopino.
English: Peripheral neuropathy and optic nerve disorders
Slovenian: Periferna nevropatija in motnje očesnega živca
English: In vitro studies have shown that drug interactions between tedizolid and inhibitors or inducers of cytochrome P450 (CYP) isoenzymes are unanticipated.
Slovenian: Študije in vitro so pokazale, da medsebojnega delovanja tedizolida in zaviralcev ali induktorjev izoencimov citokroma P450 (CYP) ni pričakovati.
English: There is limited experience with tedizolid phosphate in the treatment of patients with concomitant acute bacterial skin and skin structure infections and secondary bacteremia and no experience in the treatment of ABSSSI with severe sepsis or septic shock.
Slovenian: S tedizolid fosfatom je malo izkušenj pri zdravljenju bolnikov s sočasnimi akutnimi bakterijskimi okužbami kože in mehkih tkiv ter sekundarno bakteriemijo ter nobenih izkušenj pri zdravljenju akutnih bakterijskih okužb kože in mehkih tkiv s hudo sepso ali septičnim šokom.
English: Your doctor will decide if you should be given Sivextro to treat your infection.
Slovenian: Zdravnik bo presodil, ali je zdravilo Sivextro primerno za zdravljenje vaše okužbe.
English: CDAD may range in severity from mild diarrhoea to fatal colitis.
Slovenian: Resnost CDAD lahko sega od blage diareje do kolitisa s smrtnim izidom.
English: The median tyramine dose required to cause an increase in systolic blood pressure of ≥30 mmHg from pre-dose baseline was 325 mg with tedizolid phosphate compared to 425 mg with placebo.
Slovenian: Mediani odmerek tiramina, potreben za povzročitev zvišanja sistoličnega krvnega tlaka za ≥ 30 mmHg glede na izhodiščno vrednost pred odmerkom, je bil pri tedizolid fosfatu 325 mg in pri placebu 425 mg.
English: Tedizolid inhibits mitochondrial protein synthesis.
Slovenian: Tedizolid zavira sintezo mitohondrijskih beljakovin.
English: Tedizolid did not alter activity of selected CYP isoenzymes, but induction of CYP3A4 mRNA was observed in vitro in hepatocytes.
Slovenian: Tedizolid ni spremenil aktivnosti izbranih izoencimov CYP, vendar so in vitro opazili indukcijo CYP3A4 mRNA v hepatocitih.
English: • Infusion reactions (chills, shaking or shivering with fever, muscle pain, swelling of the face, weakness, fainting, shortness of breath, chest tightness and angina pectoris).
Slovenian: • reakcije na infuzijo (mrazenje, tresenje ali drgetanje z zvišano telesno temperaturo, bolečine v mišicah, zatečen obraz, šibkost, omedlevica, zasoplost, tiščanje v prsih in angina pektoris)
English: In vitro drug combination studies with tedizolid and amphotericin B, aztreonam, ceftazidime, ceftriaxone, ciprofloxacin, clindamycin, colistin, daptomycin, gentamicin, imipenem, ketoconazole, minocycline, piperacillin, rifampicin, terbinafine, trimethoprim/sulfamethoxazole, and vancomycin indicate that neither synergy nor antagonism have been demonstrated.
Slovenian: Študije kombinacij zdravil in vitro, opravljene s tedizolidom in amfotericinom B, aztreonamom, ceftazidimom, ceftriaksonom, ciprofloksacinom, klindamicinom, kolistinom, daptomicinom, gentamicinom, imipenemom, ketokonazolom, minociklinom, piperacilinom, rifampicinom, terbinafinom, trimetoprimom/sulfametoksazolom ter vankomicinom, niso pokazale niti sinergije niti antagonizma.
English: Tell your doctor or nurse if you are taking, have recently taken or might take any other medicines.
Slovenian: Obvestite zdravnika ali medicinsko sestro, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo.
English: The pharmacokinetics of tedizolid were similar in males and females.
Slovenian: Farmakokinetika tedizolida je bila pri moških in ženskah podobna.
English: If you forget to take Sivextro
Slovenian: Če ste pozabili vzeti zdravilo Sivextro
English: As a precautionary measure, it is preferable to avoid the use of tedizolid phosphate during pregnancy.
Slovenian: Iz previdnostnih razlogov se je med nosečnostjo uporabi tedizolid fosfata bolje izogibati.
English: Neuropathy (optic and peripheral) has not been reported in patients treated with tedizolid phosphate at the recommended treatment duration of 6 days.
Slovenian: O nevropatiji (optični in periferni) niso poročali pri bolnikih, ki so se zdravili s tedizolid fosfatom v priporočenem obdobju 6 dni.
English: • The active substance is tedizolid phosphate.
Slovenian: • Učinkovina je tedizolid fosfat.
English: Grip strength decreased Transaminases increased White blood cell count decreased
Slovenian: Preiskave šibkejši prijem zvišane ravni transaminaz zmanjšanje števila belih krvnih celic
English: • The other ingredients are mannitol, sodium hydroxide (for pH adjustment) and hydrochloric acid (for pH adjustment).
Slovenian: • Druge sestavine zdravila so manitol, natrijev hidroksid (za uravnavanje pH) in klorovodikova kislina (za uravnavanje pH).
English: The resulting solution is a clear colourless or light-yellow solution.
Slovenian: Pripravljena raztopina je bistra in brezbarvna ali svetlo rumena.
English: Efficacy has been demonstrated in clinical studies against the pathogens listed under each indication that were susceptible to tedizolid in vitro.
Slovenian: V kliničnih študijah je bila dokazana učinkovitost proti patogenom, ki so našteti pri posamezni indikaciji in so bili in vitro občutljivi za tedizolid.
English: No meaningful changes in blood pressure or heart rate were seen with pseudoephedrine.
Slovenian: Pri psevdoefedrinu niso opazili pomembnih sprememb krvnega tlaka ali srčnega utripa.
English: You will be given one 200 mg infusion of Sivextro once a day for 6 days.
Slovenian: Eno infuzijo z 200 mg odmerkom zdravila Sivextro boste enkrat dnevno prejemali 6 dni.
English: The tablets are swallowed whole and can be taken with or without food or drink.
Slovenian: Lahko se jemljejo sočasno s hrano in pijačo ali brez njiju.
English: Embryo-foetal development studies in mice and rats showed no evidence of a teratogenic effect at exposure levels 4-fold and 6-fold, respectively, those expected in humans.
Slovenian: Študije razvoja zarodka/plodu pri miših in podganah niso pokazale znakov teratogenega delovanja pri izpostavljenosti, ki je bila 4- oziroma 6-krat večja od pričakovane stopnje izpostavljenosti pri človeku.
English: The potential for tedizolid or tedizolid phosphate to inhibit transport of probe substrates of important drug uptake (OAT1, OAT3, OATP1B1, OATP1B3, OCT1, and OCT2) and efflux transporters (P-gp and BCRP) was tested in vitro.
Slovenian: In vitro so testirali potencial tedizolida ali tedizolid fosfata za zaviranje transporta preiskovanih substratov pomembnih prenašalcev za privzem zdravil (OAT1, OAT3, OATP1B1, OATP1B3, OCT1 in OCT2) in efluksnih prenašalcev (P-gp in BCRP).
English: What Sivextro is and what it is used for What you need to know before you are given Sivextro How you will be given Sivextro Possible side effects
Slovenian: Kaj je zdravilo Sivextro in za kaj ga uporabljamo Kaj morate vedeti, preden boste prejeli zdravilo Sivextro Kako boste prejeli zdravilo Sivextro Možni neželeni učinki
English: Sivextro is incompatible with any solutions containing divalent cations (e.g., Ca
Slovenian: Zdravilo Sivextro je inkompatibilno z vsemi raztopinami, ki vsebujejo dvovalentne katione (npr. Ca
English: Table 1 Frequency of adverse reactions by System Organ Class in pooled Phase 3 comparative clinical studies
Slovenian: Preglednica 1 Pogostnost neželenih učinkov po organskih sistemih v združenih primerjalnih kliničnih študijah 3. faze
English: In a mouse thigh infection model of S. aureus, the antibacterial activity of tedizolid was reduced in the absence of granulocytes.
Slovenian: Pri mišjem modelu okužbe stegna z bakterijo S. aureus se je protibakterijsko delovanje tedizolida zmanjšalo v odsotnosti granulocitov.
English: Sivextro is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults (see sections 4.4 and 5.1).
Slovenian: Zdravilo Sivextro je indicirano za zdravljenje akutnih bakterijskih okužb kože in mehkih tkiv (ABSSSI - acute bacterial skin and skin structure infections) pri odraslih (glejte poglavji 4.4 in 5.1).
English: • sulfasalazine (used to treat inflammatory bowel diseases)
Slovenian: • sulfasalazin (za zdravljenje vnetnih črevesnih bolezni)
English: Do not shake the bag.
Slovenian: Infuzijske vrečke ne stresajte.
English: Other medicines and Sivextro
Slovenian: Druga zdravila in zdravilo Sivextro
English: If you stop taking Sivextro
Slovenian: Če ste prenehali jemati zdravilo Sivextro
English: • Acid reflux disease (heartburn, pain or difficulty swallowing), flatulence/passing wind
Slovenian: • bolezen refluksa kisline (zgaga, bolečine ali težave pri požiranju), napenjanje/vetrovi
English: Tedizolid is excreted in the breast milk of rats (see section 5.3).
Slovenian: Tedizolid se pri podganah izloča v mleko (glejte poglavje 5.3).
English: Do not use this medicine after the expiry date which is stated on the carton or blister label after “EXP”.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli, pretisnem omotu ali nalepki poleg oznake "EXP".
English: The antibacterial activity of tedizolid is mediated by binding to the 50S subunit of the bacterial ribosome resulting in inhibition of protein synthesis.
Slovenian: Protibakterijsko delovanje tedizolida poteka preko vezave na podenoto 50S bakterijskega ribosoma, kar zavre sintezo beljakovin.
English: • a low white blood cell count
Slovenian: • majhno število belih krvnih celic,
English: Susceptible (≤S) Resistant (R>)
Slovenian: Odporni (R >)
English: Lactic acidosis has not been reported in patients treated with tedizolid phosphate at the recommended treatment duration of 6 days.
Slovenian: O laktacidozi niso poročali pri bolnikih, ki so se zdravili s tedizolid fosfatom v priporočenem obdobju 6 dni.
English: Tedizolid phosphate had no adverse effects on the fertility or reproductive performance of male rats, including spermatogenesis, at oral doses up to the maximum tested dose of 50 mg/kg/day, or adult female rats at oral doses up to the maximum tested dose of 15 mg/kg/day.
Slovenian: Tedizolid fosfat ni imel škodljivih učinkov na plodnost ali sposobnost razmnoževanja podganjih samcev, niti na spermatogenezo, pri peroralnih odmerkih do največjega preskušanega odmerka 50 mg/kg/dan, ali odraslih podganjih samic pri peroralnih odmerkih do največjega preskušanega odmerka 15 mg/kg/dan.
English: In a 1-month immunotoxicology study in rats, repeated oral dosing of tedizolid phosphate was shown to significantly reduce splenic B cells and T cells and reduce plasma IgG titers.
Slovenian: Enomesečna imunotoksikološka študija na podganah je pokazala, da ponavljajoči peroralni odmerki tedizolid fosfata pomembno zmanjšajo vranične celice B in celice T ter zmanjšajo plazemske titre IgG.
English: • loss of sensitivity in your hands or feet (such as numbness, prickling/tingling, or sharp pains)
Slovenian: • izgubo občutljivosti v dlaneh ali stopalih (kot so otrplost, zbadanje/mravljinčenje ali ostre bolečine),
English: No dose adjustment is necessary for co-administered CYP3A4 substrates during treatment with Sivextro.
Slovenian: Prilagoditev odmerkov sočasno uporabljenih substratov CYP3A4 med zdravljenjem z zdravilom Sivextro ni potrebna.
English: Tedizolid is generally not active against Gram-negative bacteria.
Slovenian: Tedizolid običajno ne deluje proti gramnegativnim bakterijam.
English: Tedizolid is eliminated in excreta, primarily as a non-circulating sulfate conjugate.
Slovenian: Tedizolid se izloča s telesnimi izločki, zlasti v obliki sulfatnega konjugata, ki ni prisoten v obtoku.
English: Patients should not take a double dose to compensate for a missed dose.
Slovenian: Bolnik ne sme prejeti dvojnega odmerka, da bi nadomestil izpuščeni odmerek.
English: • Abscess (swollen, pus-filled lump)
Slovenian: • absces (otečena zatrdlina, napolnjena z gnojem)
English: The mean Cmax and AUC0-∞ for oral or IV administration of tedizolid phosphate 200 mg were similar in adolescent and in healthy adult subjects.
Slovenian: Povprečni vrednosti Cmax in AUC0-∞ po peroralni ali intravenski uporabi tedizolid fosfata v odmerku 200 mg sta bili podobni pri mladostnikih in zdravih odraslih.
English: Lactic acidosis has been reported with the use of another member of the oxazolidinone class.
Slovenian: O laktacidozi so poročali pri uporabi drugega zdravila iz skupine oksazolidinonov.
English: These effects occurred at plasma tedizolid exposure levels (AUC) ≥3-fold greater than the expected human plasma exposure associated with the therapeutic dose.
Slovenian: Ti učinki so se pojavili pri plazemski izpostavljenosti tedizolidu (AUC), ki je bila ≥ 3-krat večja od pričakovane plazemske izpostavljenosti, povezane s terapevtskim odmerkom pri človeku.
English: Tedizolid is primarily active against Gram-positive bacteria.
Slovenian: Tedizolid deluje primarno proti grampozitivnim bakterijam.
English: Blood and lymphatic system disorders
Slovenian: Bolezni krvi in limfatičnega sistema limfadenopatija
English: No clinically relevant interactions are expected to occur with these transporters, with the administration of the parenteral formulation.
Slovenian: Pri teh prenašalcih klinično pomembnega medsebojnega delovanja, pri uporabi parenteralne oblike zdravila, ni pričakovati.
English: No clinically relevant interactions are expected to occur with these transporters, with the exception of BCRP.
Slovenian: Pri teh prenašalcih, razen pri prenašalcu BCRP, klinično pomembnega medsebojnega delovanja ni pričakovati.
English: Foetal developmental effects occurring in mice in the absence of maternal toxicity included reduced foetal weights and an increased incidence of costal cartilage fusion (an exacerbation of the normal genetic predisposition to sternal variations in the CD-1 strain of mice) at the high dose of 25 mg/kg/day (4-fold the estimated human exposure level based on AUCs).
Slovenian: Med učinki na razvoj plodu, ki so se pojavljali pri miših v odsotnosti toksičnosti za mater, sta zmanjšana masa plodu in povečana pojavnost fuzije rebrnega hrustanca (poslabšanje normalne genetske nagnjenosti k variacijam prsnice pri mišjem sevu CD-1) pri velikem odmerku 25 mg/kg/dan (4-kratnik ocenjene ravni izpostavljenosti pri človeku, ki temelji na vrednostih AUC).
English: Acute bacterial skin and skin structure infections
Slovenian: Akutne bakterijske okužbe kože in mehkih tkiv
English: Haemodialysis does not result in meaningful removal of tedizolid from systemic circulation, as assessed in subjects with endstage renal disease (eGFR <15 mL/min).
Slovenian: Hemodializa ne odstrani pomembne količine tedizolida iz sistemskega krvnega obtoka, kar so ocenili pri preiskovancih s končno odpovedjo ledvic (eGFR < 15 ml/min).
English: Two placebo-controlled crossover studies were conducted to assess the potential of 200 mg oral tedizolid phosphate at steady state to enhance pressor responses to pseudoephedrine and tyramine in healthy individuals.
Slovenian: Opravili so dve s placebom nadzorovani navzkrižni študiji za oceno potenciala 200 mg peroralnega odmerka tedizolid fosfata, da v stanju dinamičnega ravnovesja poveča presorne odzive na psevdoefedrin in tiramin pri zdravih posameznikih.
English: Sivextro is an antibiotic that contains the active substance tedizolid phosphate.
Slovenian: Zdravilo Sivextro je antibiotik, ki vsebuje učinkovino tedizolid fosfat.
English: Sivextro must be reconstituted with water for injections and subsequently diluted in 250 mL of 0.9% sodium chloride for infusion.
Slovenian: Zdravilo Sivextro je treba rekonstituirati z vodo za injekcije in nato razredčiti v 250 ml 0,9-odstotne raztopine natrijevega klorida za injiciranje.
English: Spontaneous reports of serotonin syndrome associated with the co-administration of another member of the oxazolidinone class together with serotonergic agents have been reported (see section 4.5).
Slovenian: Prejeta so bila spontana poročila o serotoninskem sindromu, povezanem s sočasno uporabo drugega zdravila iz skupine oksazolidinonov s serotoninergičnimi zdravili (glejte poglavje 4.5).
English: These effects showed evidence of reversibility and occurred at plasma tedizolid exposure levels (AUC) ≥6-fold greater than the plasma exposure associated with the human therapeutic dose.
Slovenian: Ti učinki so kazali znake reverzibilnosti in so se pojavili pri plazemski izpostavljenosti tedizolidu (AUC), ki je bila ≥ 6-krat večja od plazemske izpostavljenosti, povezane s terapevtskim odmerkom pri človeku.
English: The contents of the vial should be reconstituted with 4 mL of water for injections, and be swirled gently until the powder has dissolved entirely.
Slovenian: Vsebino viale je treba rekonstituirati s 4 ml vode za injekcije in vialo nežno obračati, dokler se prašek popolnoma ne raztopi.
English: Peak concentrations (Cmax) of tedizolid are reduced by approximately 26% and delayed by 6 hours when tedizolid phosphate is administered after a high-fat meal relative to fasted, while total exposure (AUC0-∞) is unchanged between fasted and fed conditions.
Slovenian: V primerjavi z odmerjanjem na tešče se najvišje koncentracije (Cmax) tedizolida znižajo za približno 26 % in zakasnijo za 6 ur, če se tedizolid fosfat zaužije po mastnem obroku, medtem ko pri skupni izpostavljenosti (AUC0-∞) ni razlike med teščim stanjem in stanjem po obroku.
English: Following administration of a single 200 mg IV dose of tedizolid phosphate to 8 subjects with severe renal impairment defined as eGFR <30 mL/min, the Cmax was basically unchanged and AUC0-∞ was changed by less than 10% compared to 8 matched healthy subject controls.
Slovenian: Po aplikaciji enkratnega 200 mg intravenskega odmerka tedizolid fosfata 8 preiskovancem s hudo okvaro ledvic, opredeljeno kot eGFR < 30 ml/min, se vrednost Cmax v bistvu ni spremenila, vrednost AUC0-∞ pa se je spremenila za manj kot 10 % v primerjavi z 8 odgovarjajočimi zdravimi preiskovanci iz kontrolne skupine.
English: Tedizolid phosphate is an oxazolidinone phosphate prodrug.
Slovenian: Tedizolid fosfat je oksazolidinonsko fosfatno predzdravilo.
English: • Respiratory tract (sinuses, throat and chest) infection
Slovenian: • okužba dihal (sinusov, grla in prsnega koša)
English: The pharmacokinetics of tedizolid were evaluated in adolescent subjects (12 to 17 years; n=20) following administration of a single oral or IV dose of tedizolid phosphate 200 mg.
Slovenian: Farmakokinetiko tedizolida so ocenili pri mladostnikih (od 12 do 17 let, n = 20) po uporabi enkratnega 200 mg peroralnega ali intravenskega odmerka tedizolid fosfata.
English: The reconstituted solution must be administered as an intravenous infusion only.
Slovenian: Rekonstituirana raztopina se sme aplicirati samo z intravensko infuzijo.
English: There is no Phase 3 clinical experience in patients with co-administration of tedizolid phosphate with serotonergic agents such as selective serotonin re-uptake inhibitors [SSRI], serotonin norepinephrine reuptake inhibitors (SNRI), tricyclic antidepressants, MAO inhibitors, triptans, and other medicines with potential adrenergic or serotonergic activity.
Slovenian: Kliničnih izkušenj 3. faze ni na voljo pri bolnikih, ki se sočasno zdravijo s tedizolid fosfatom in serotoninergičnimi zdravili, kot so selektivni zaviralci ponovnega privzema serotonina [SSRI], zaviralci ponovnega privzema serotonina in noradrenalina (SNRI), triciklični antidepresivi, zaviralci MAO, triptani in druga zdravila, ki lahko delujejo adrenergično ali serotoninergično.
English: Tedizolid is excreted into the milk of lactating rats and the concentrations observed similar to those in maternal plasma.
Slovenian: Pri doječih podganah se tedizolid izloča v mleko v koncentracijah, podobnih koncentracijam v plazmi mater.