FrancophonIA/ELRC3.0 huggingface dataset:
English: Valdecoxib is not removed by haemodialysis.
Slovenian: Hemodializa ne odstrani valdekoksiba.
English: After reconstitution, the liquid should be a clear solution.
Slovenian: Po rekonstituciji mora biti tekočina bistra raztopina.
English: 1 + 1 pack: contains 1 powder vial and 1 solvent ampoule.
Slovenian: Pakiranje 1 + 1: vsebuje 1 vialo praška in 1 ampulo vehikla.
English: In post-marketing experience, toxic epidermal necrolysis has been reported in association with the use of valdecoxib, and cannot be ruled out for parecoxib (see section 4.4).
Slovenian: Med izkušnjami v obdobju trženja je bila toksična epidermalna nekroliza opisana v zvezi z uporabo valdekoksiba in je ni mogoče izključiti tudi pri parekoksibu (glejte poglavje 4.4).
English: The IV bolus injection may be given rapidly and directly into a vein or into an existing IV line.
Slovenian: bolusno injekcijo pa se lahko daje hitro in neposredno v veno ali v obstoječo intravensko pot.
English: Exposure to valdecoxib was similar in terms of AUC and Cmax following IV and IM administration.
Slovenian: Izpostavljenost valdekoksibu je bila glede na AUC in Cmax po intravenski in intramuskularni uporabi podobna.
English: Inhibition of prostaglandins by NSAIDs, including COX-2 inhibitors, may diminish the effect of angiotensin converting enzyme (ACE) inhibitors, angiotensin II antagonists, beta-blockers and diuretics.
Slovenian: Zaviralni učinek nesteroidnih protivnetnih zdravil, vključno z zaviralci COX-2, na prostaglandine lahko zmanjša učinek zaviralcev angiotenzinske konvertaze (ACE - angiotensin converting enzyme), antagonistov angiotenzina II, antagonistov adrenergičnih receptorjev beta in diuretikov.
English: ▪ If you have previously had an ulcer, bleeding or perforation of the gastrointestinal tract.
Slovenian: • če ste kdaj prej imeli razjedo, krvavitev ali predrtje (perforacijo) v prebavilih
English: What Dynastat looks like and contents of the pack Dynastat is available as a white to off-white powder.
Slovenian: Zdravilo Dynastat je na voljo v obliki belega do belkastega praška.
English: Plasma exposure (AUC and Cmax) to valdecoxib was increased (62% and 19%, respectively) when coadministered with fluconazole (predominantly a CYP2C9 inhibitor), indicating that the dose of parecoxib should be reduced in those patients who are receiving fluconazole therapy.
Slovenian: Plazemska izpostavljenost (AUC in Cmax) valdekoksibu se je med sočasno uporabo flukonazola (ki zavira predvsem CYP2C9) povečala (AUC za 62 % in Cmax za 19 %); kar kaže, da je treba pri bolnikih, ki dobivajo flukonazol, odmerek parekoksiba zmanjšati.
English: The powder is contained in colourless glass vials (5 ml) with a stopper, sealed with a purple flip-off cap on the aluminium overseal.
Slovenian: Prašek je pakiran v brezbarvne steklene viale (5 ml) z zamaškom, zaščitenim s prevleko iz aluminija, ki ima na sredini vijolično pretržno zaporko, ki se odstrani na poteg.
English: Reconstitution process
Slovenian: Postopek rekonstitucije
English: Dynastat is preservative free.
Slovenian: Zdravilo Dynastat ne vsebuje konzervansov.
English: Vascular disorders Hypertension, hypotension
Slovenian: Hipertenzija, hipotenzija
English: In a placebo-controlled, orthopedic and general surgery study (n =1050), patients received Dynastat at an initial parenteral dose of 40 mg IV followed by 20 mg twice daily for a minimum of 72 hours in addition to receiving standard care including supplemental patient controlled opioids.
Slovenian: V študiji na področju ortopedije in splošne kirurgije (n = 1050), ki je bila nadzorovana s placebom, so bolniki prejeli zdravilo Dynastat v začetnem parenteralnem odmerku 40 mg i.v., kateremu je sledil odmerek 20 mg dvakrat na dan, najmanj 72 ur.
English: The first CABG surgery study evaluated patients treated with IV parecoxib 40 mg bid for a minimum of 3 days, followed by treatment with valdecoxib 40 mg bid (parecoxib/valdecoxib group) (n=311) or placebo/placebo (n=151) in a 14-day, double-blind placebo-controlled study.
Slovenian: parekoksibom 40 mg dvakrat na dan najmanj 3 dni, čemur je sledilo zdravljenje z valdekoksibom 40 mg dvakrat na dan (skupina parekoksib/valdekoksib) (n = 311), ali prejemanje placeba/placeba (n = 151) v 14-dnevni dvojno slepi s placebom nadzorovani študiji.
English: There were no significant differences between active treatments and placebo for any of the other pre-specified event categories (renal dysfunction/failure, upper GI ulcer complications or surgical wound complications).
Slovenian: Aktivno zdravljenje se ni pomembno razlikovalo od placeba glede nobene vnaprej opredeljene kategorije pojavov (moteno delovanje ledvic/ledvična odpoved, zapleti z razjedami v zgornjih prebavilih ali zapleti kirurške rane).
English: Psychiatric disorders Agitation, insomnia Nervous system disorders Hypoaesthesia, dizziness
Slovenian: Psihiatrične motnje Agitiranost, nespečnost Bolezni živčevja Hipestezija, omotica
English: Following single IV and IM doses of parecoxib 20 mg, Cmax of valdecoxib is achieved in approximately 30 minutes and approximately 1 hour, respectively.
Slovenian: odmerkih 20 mg parekoksiba je Cmax valdekoksiba dosežena v približno 30 minutah (i.v.)
English: On the basis of pharmacokinetics, no dose adjustment is necessary in patients with mild to moderate renal impairment (creatinine clearance of 30-80 ml/min.
Slovenian: Glede na farmakokinetiko, bolnikom z blago do zmerno okvaro ledvic (očistek kreatinina 30-80 ml/min), odmerka ni treba prilagoditi.
English: OUTER CARTON: 40 mg vials
Slovenian: ZUNANJA ŠKATLA: 40 mg viale
English: Sodium chloride 9 mg/ml (0.9%) solution
Slovenian: Raztopina natrijevega klorida 9 mg/ml (0,9 %)
English: Patients should be adequately hydrated and the need to monitor the renal function should be assessed at the beginning of the concomitant treatment and periodically thereafter.
Slovenian: Na začetku sočasnega zdravljenja in občasno tudi kasneje je treba oceniti potrebo po spremljanju ledvične funkcije.
English: 40 mg vial: Remove the purple flip-off cap to expose the central portion of the rubber stopper of the parecoxib 40 mg vial.
Slovenian: 40-mg viala: Odstranite vijolično pretržno zaporko, da boste razkrili osrednji del gumijastega zamaška 40-mg viale parekoksiba.
English: Active peptic ulceration or gastrointestinal (GI) bleeding.
Slovenian: Aktivna peptična razjeda ali krvavitev v prebavilih.
English: Skin and subcutaneous tissue disorders Pruritus, hyperhidrosis
Slovenian: Bolezni kože in podkožja Srbenje, hiperhidroza
English: Dynastat has not been studied in cardiovascular revascularization procedures other than coronary artery bypass graft (CABG) procedures.
Slovenian: Zdravilo Dynastat, razen v študijo operacij obvodov koronarne arterije (CABG - coronary artery bypass graft), ni bilo vključeno v nobeno drugo študijo kardiovaskularnih kirurških postopkov revaskularizacije.
English: Patients without a history of sulfonamide allergy may also be at risk for serious skin reactions.
Slovenian: Tveganje za pojav resnih kožnih reakcij je lahko prisotno tudi pri bolnikih, ki nimajo alergije na sulfonamid v anamnezi.
English: In the second CABG surgery study, four pre-specified event categories were evaluated (cardiovascular/thromboembolic; renal dysfunction/renal failure; upper GI ulcer/bleeding; surgical wound complication).
Slovenian: V drugi študiji v zvezi z operativnim posegom CABG so ocenjevali štiri vnaprej določene kategorije dogodkov (kardiovaskularni/trombembolični, poslabšano delovanje/odpoved ledvic, razjeda v zgornjih prebavilih/krvavenje, zapleti v zvezi s kirurško rano).
English: When reconstituted in sodium chloride 9 mg/ml (0.9%) solution, Dynastat contains approximately 0.44 mEq of sodium per vial.
Slovenian: Po rekonstituciji z 9 mg/ml (0,9 %) raztopino natrijevega klorida zdravilo Dynastat vsebuje približno 0,44 mEq natrija na vialo.
English: • Ringer-Lactate solution for injection.
Slovenian: • raztopina Ringerjevega laktata za injiciranje.
English: In surgery studies in which parecoxib was administered pre-operatively, no evidence of pharmacodynamic interaction was observed in patients receiving parecoxib and the inhalation anaesthetic agents nitrous oxide and isoflurane (see section
Slovenian: V kirurških študijah, v katerih so parekoksib uporabili pred operacijo, pri bolnikih, ki so dobivali parekoksib in inhalacijska anestetika dušikov oksid in izofluran, niso ugotovili nobenih farmakodinamičnih interakcij (glejte poglavje 5.1).
English: Caution should be exercised when coadministering Dynastat with warfarin and other oral anticoagulants (see section 4.5).
Slovenian: Pri sočasni uporabi zdravila Dynastat in varfarina ali drugih peroralnih antikoagulantov je potrebna previdnost (glejte poglavje 4.5).
English: COX-2 inhibitors have been associated with increased risk of cardiovascular and thrombotic adverse events when taken long term.
Slovenian: Dolgotrajna uporaba zaviralcev COX-2 je bila povezana s povečanim tveganjem za srčnožilne in trombotične neželene dogodke.
English: Plasma protein binding is approximately 98% over the concentration range achieved with the highest recommended dose, 80 mg/day.
Slovenian: V koncentracijskem območju, doseženem z največjim priporočenim odmerkom 80 mg/dan, je vezava na beljakovine v plazmi približno 98 %.
English: VIAL LABEL: 40 mg
Slovenian: NALEPKA NA VIALI: 40 mg
English: Dynastat has been studied in dental, orthopaedic, gynaecologic (principally hysterectomy) and coronary artery bypass graft surgery.
Slovenian: Zdravilo Dynastat so preučevali pri stomatoloških, ortopedskih in ginekoloških (predvsem histerektomiji) operacijah in obvodni operaciji koronarnih arterij.
English: The reconstituted solution must not be used if discoloured or cloudy or if particulate matter is observed.
Slovenian: Rekonstituirane raztopine ne smete uporabiti, če je obarvana, motna ali so v njej delci.
English: What Dynastat contains - The active substance is parecoxib (as parecoxib sodium).
Slovenian: Kaj vsebuje zdravilo Dynastat - Učinkovina je parekoksib (v obliki natrijevega parekoksibata).
English: After reconstitution with acceptable solvents, Dynastat may only be injected IV or IM, or into IV lines delivering:
Slovenian: Po rekonstituciji z dovoljenim vehiklom smemo zdravilo Dynastat injicirati samo intravensko ali intramuskularno, ali v intravensko pot, po kateri teče:
English: When reconstituted in sodium chloride 9 mg/ml (0.9%) solution, Dynastat contains approximately 0.44 mmol of sodium per vial.
Slovenian: Po rekonstituciji z 9 mg/ml (0,9 %) raztopino natrijevega klorida vsebuje zdravilo Dynastat približno 0,44 mmol natrija na vialo.
English: Elimination of valdecoxib is by extensive hepatic metabolism involving multiple pathways, including cytochrome P 450 (CYP) 3A4 and CYP2C9 isoenzymes and glucuronidation (about 20%) of the sulfonamide moiety.
Slovenian: Izločanje valdekoksiba poteka z obsežno presnovo v jetrih, ki vključuje več poti, med drugim izoencima CYP3A4 in CYP2C9 citokroma P450
English: In isolated cases, an aggravation of soft tissue infections has been described in connection with the use of NSAIDs and in nonclinical studies with Dynastat (see section 5.3).
Slovenian: Pri posameznikih so v zvezi z nesteroidnimi protivnetnimi zdravili in v nekliničnih študijah z zdravilom Dynastat opisali poslabšanje okužbe mehkih tkiv (glejte poglavje 5.3).
English: Caution is advised in the treatment of patients most at risk of developing a gastrointestinal complication with NSAIDs; the elderly, or patients with a prior history of gastrointestinal disease, such as ulceration and GI bleeding, or patients using acetylsalicylic acid concomitantly.
Slovenian: Med zdravljenjem je potrebna previdnost pri bolnikih, ki jih ob uporabi nesteroidnih protivnetnih zdravil najbolj ogrožajo zapleti na prebavilih, pri starejših, pri bolnikih z anamnezo bolezni prebavil, npr. razjedami ali krvavitvami v prebavilih, ali pri bolnikih, ki sočasno jemljejo acetilsalicilno kislino.
English: or patients who may be predisposed to fluid retention, parecoxib should be initiated at the lowest recommended dose (20 mg) and the patient's kidney function should be closely monitored (see sections 4.4 and 5.2).
Slovenian: Bolnikom s hudo okvaro ledvic (očistek kreatinina < 30 ml/min) ali bolnikom, nagnjenim k zastoju tekočine, je treba parekoksib uvesti v najmanjšem priporočenem odmerku (20 mg), bolnikovo delovanje ledvic pa je treba natančno nadzirati (glejte poglavji 4.4 in 5.2).
English: Additionally, coadministration of valdecoxib had no clinically significant effect on the hepatic or intestinal CYP 3A4-mediated metabolism of orally administered midazolam.
Slovenian: Poleg tega sočasna uporaba valdekoksiba ni klinično pomembno vplivala na jetrno ali črevesno presnovo (posredovano s CYP3A4) peroralno uporabljenega midazolama.
English: Dynastat had no effect on acetylsalicylic acid-mediated inhibition of platelet aggregation or bleeding times.
Slovenian: Zdravilo Dynastat ne vpliva na zavrtje agregacije trombocitov ali čas krvavitev, povezanih z acetilsalicilno kislino.
English: 5 vials and 5 solvent ampoules
Slovenian: 5 vial s praškom in 5 ampul z vehiklom
English: 1 vial and 1 solvent ampoule
Slovenian: 1 viala s praškom in 1 ampula z vehiklom
English: Intravenous or intramuscular use
Slovenian: samo za enkratno uporabo za intravensko ali intramuskularno uporabo
English: Rare (1/10,000 to <1/1000)
Slovenian: Redki ( 1/10.000 do
English: Serious skin reactions are known to occur with NSAIDs including COX-2 selective inhibitors as well as other medicinal products.
Slovenian: Znano je, da se med uporabo nesteroidnih protivnetnih zdravil, vključno s selektivnimi zaviralci COX-2, in tudi drugih zdravil pojavljajo resne kožne reakcije.
English: Reporting of overdose with parecoxib has been associated with adverse reactions which have also been described with recommended doses of parecoxib.
Slovenian: Neželeni učinki iz poročil o prekomernem odmerjanju parekoksiba so bili opisani tudi pri uporabi priporočenih odmerkov parekosiba.
English: Patients received low-dose acetylsalicylic acid prior to randomization and throughout the two CABG surgery studies.
Slovenian: Bolniki so pred randomizacijo in ves čas obeh študij obvodne operacije koronarnih arterij dobivali nizek odmerek acetilsalicilne kisline.
English: COX-2 inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effects.
Slovenian: Acetilsalicilna kislina in druga nesteroidna protivnetna zdravila Ker zaviralci COX-2 nimajo antiagregacijskega delovanja, niso nadomestilo za acetilsalicilno kislino v profilaksi kardiovaskularnih trombemboličnih bolezni.
English: Solvent for Dynastat 40 mg
Slovenian: vehikel za Dynastat 40 mg
English: After reconstitution with 2 ml of solvent, the concentration of parecoxib is 20 mg/ml.
Slovenian: Po rekonstituciji z 2 ml vehikla znaša koncentracija parekoksiba 20 mg/ml.
English: The following adverse reactions were reported for patients who received parecoxib (N=5,402) in 28 placebo-controlled clinical trials.
Slovenian: V 28 s placebom nadzorovanih kliničnih preskušanjih so poročali o naslednjih neželenih učinkih pri bolnikih, ki so prejemali parekoksib (N = 5.402).
English: C.
Slovenian: I.m.
English: Talk to your doctor or nurse before using Dynastat:
Slovenian: Pred začetkom uporabe zdravila Dynastat se posvetujte z zdravnikom ali medicinsko sestro:
English: Parecoxib administered intravenously to lactating rats as a single dose showed concentrations of parecoxib, valdecoxib and a valdecoxib active metabolite in milk similar to that of maternal plasma.
Slovenian: Po aplikaciji enkratnega intravenskega odmerka parekoksiba doječim podganam so se parekoksib, valdekoksib in aktivni presnovek valdekoksiba v mleku pojavili v podobni koncentraciji, kot v plazmi doječe podgane.
English: However, for elderly patients weighing less than 50 kg, treatment should be initiated with half the usual recommended dose of Dynastat and reduce the maximum daily dose to 40 mg (see section 5.2).
Slovenian: Starejšim bolnikom (≥ 65 let) odmerka praviloma ni treba prilagajati; če pa tehtajo manj kot 50 kg, pa je treba zdravljenje kljub temu začeti s polovičnim običajnim priporočenim odmerkom zdravila Dynastat, maksimalni dnevni odmerek pa zmanjšati na 40 mg (glejte poglavje 5.2).
English: Parecoxib is a prodrug of valdecoxib.
Slovenian: Parekoksib je predzdravilo valdekoksiba.
English: Asthenia, injection site pain, injection site reaction
Slovenian: • bolečina na mestu injiciranja ali reakcija na mestu injiciranja
English: Gastrointestinal disorders Nausea Abdominal pain, vomiting, constipation, dyspepsia, flatulence
Slovenian: Bolezni prebavil Navzea Bolečina v trebuhu, bruhanje, zaprtost, dispepsija, flatulenca
English: Remove the purple flip-off cap to expose the central portion of the rubber stopper of the 40 mg parecoxib vial.
Slovenian: Odstranite vijolično pretržno zaporko, da boste razkrili osrednji del gumijastega zamaška viale s 40 mg parekoksiba.
English: Pregnancy, breast-feeding and fertility ▪ If you are pregnant or trying to become pregnant, tell your doctor.
Slovenian: • Če ste noseči ali poizkušate zanositi, to povejte zdravniku.
English: Adequate monitoring of methotrexate-related toxicity should be considered when coadministering parecoxib and methotrexate.
Slovenian: Med sočasno uporabo parekoksiba in metotreksata je zato treba razmisliti o ustreznem spremljanju z metotreksatom povezanih toksičnih učinkov.
English: No effects of parecoxib on male or female fertilities were found in rats.
Slovenian: Pri podganah niso ugotovili, da bi parekoksib vplival na plodnost samcev ali samic.
English: Powder for solution for injection
Slovenian: prašek za raztopino za injiciranje
English: Additionally, fatal reports of toxic epidermal necrolysis have been reported through postmarketing surveillance in patients receiving valdecoxib (the active metabolite of parecoxib) and cannot be ruled out for parecoxib (see section 4.8).
Slovenian: Dodatno so v študijah v obdobju trženja pri bolnikih, ki so prejemali valdekoksib (aktivni presnovek parekoksiba), poročali o toksični epidermalni nekrolizi s smrtnim izidom; pojava le-teh ni mogoče izključiti pri uporabi parekoksiba (glejte poglavje 4.8).
English: Type I colourless glass vials (5 ml) with a butyl rubber stopper, sealed with a purple polypropylene flip-off cap on the aluminium overseal.
Slovenian: 5 ml steklene viale iz brezbarvnega stekla tipa I z zamaškom iz butilne gume, zaščitenim s prevleko iz aluminija, ki ima na sredini vijolično polipropilensko pretržno zaporko, ki se odstrani na poteg.
English: There were no significant differences in the overall safety profile, including the four pre-specified event categories described above for the second CABG surgery study, for parecoxib/valdecoxib compared to placebo treatment in these post-surgical patients.
Slovenian: Pri bolnikih po prestani operaciji pri prejemanju parekoksiba/valdekoksiba v primerjavi s prejemanjem placeba niso zaznali nobenih pomembnih razlik v splošnem varnostnem profilu, vključno s predhodno določenimi štirimi kategorijami v zvezi z drugo študijo operacije CABG, ki so opisane zgoraj.
English: Exposure to parecoxib was similar after IV or IM administration in terms of AUC.
Slovenian: Izpostavljenost parekoksibu je bila glede na AUC po intravenski in intramuskularni uporabi podobna.
English: Fluid retention, oedema, renal
Slovenian: Zastajanje tekočine, edemi, ledvica
English: Valdecoxib is a selective COX-2 inhibitor within the clinical dose range.
Slovenian: Valdekoksib v območju kliničnih odmerkov selektivno zavira COX-2.
English: Hydrochloric acid or sodium hydroxide (for pH adjustment) Water for injection.
Slovenian: Vehikel natrijev klorid klorovodikova kislina ali natrijev hidroksid (za uravnavanje pH) voda za injekcije
English: 3 vials and 3 solvent ampoules
Slovenian: 3 viale s praškom in 3 ampule z vehiklom
English: Each 2 ml of reconstituted powder contains 40 mg of parecoxib.
Slovenian: 2 ml rekonstituiranega praška vsebuje 40 mg parekoksiba.
English: The recommended dose is 40 mg administered intravenously (IV) or intramuscularly (IM), followed every 6 to 12 hours by 20 mg or 40 mg as required, not to exceed 80 mg/day.
Slovenian: ), ter nato vsakih 6 do 12 ur 20 mg ali 40 mg, glede na potrebo, vendar ne več kot 80 mg/dan.
English: After reconstitution, the concentration of parecoxib is 20 mg/ml.
Slovenian: Koncentracija parekoksiba po rekonstituciji je 20 mg/ml.
English: Use of Ringer-Lactate solution for injection or glucose 50 mg/ml (5%) in Ringer Lactate solution for injection for reconstitution will cause the parecoxib to precipitate from solution and therefore is not recommended.
Slovenian: Rekonstitucija raztopine natrijevega parekoksibata z uporabo raztopine Ringerjevega laktata za injiciranje ali 50 mg/ml (5 %) glukoze v raztopini Ringerjevega laktata za injiciranje povzroči precipitacijo parekoksiba iz raztopine in zato ni priporočljiva.
English: - If you get any side effects, talk to your doctor or nurse.
Slovenian: - Če opazite katerikoli neželeni učinek, se posvetujte z zdravnikom ali medicinsko sestro.
English: Hypersensitivity reactions (anaphylaxis and angioedema) have been reported in post-marketing experience with valdecoxib and parecoxib (see section 4.8).
Slovenian: Med izkušnjami z valdekoksibom in parekoksibom so v obdobju trženja poročali o preobčutljivostnih reakcijah (anafilaksa in angioedem) (glejte poglavje 4.8).
English: If any of these applies to you, you will not be given the injection.
Slovenian: Če karkoli od naštetega velja za vas, injekcije ne boste dobili, zato morate o tem nemudoma obvestiti zdravnika ali medicinsko sestro.
English: Serious skin reactions, including erythema multiforme, exfoliative dermatitis and Stevens-Johnson syndrome (some of them fatal) have been reported through post-marketing surveillance in patients receiving parecoxib.
Slovenian: V študijah v obdobju trženja so pri bolnikih, ki so prejemali parekoksib, poročali o hudih kožnih reakcijah, vključno z multiformnim eritemom, eksfoliativnim dermatitisom in Stevens-Johnsonovim sindromom (nekateri s smrtnim izidom).
English: As the cardiovascular risk of cyclooxygenase-2 (COX-2) specific inhibitors may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used.
Slovenian: Kardiovaskularno tveganje zaradi specifičnih zaviralcev ciklooksigenaze-2 (COX-2) se lahko poveča s povečevanjem odmerka in s trajanjem izpostavljenosti zdravilu.
English: Pancreatitis, oesophagitis, oedema mouth (perioral swelling)
Slovenian: Pankreatitis, ezofagitis, edem ust (perioralna oteklina)
English: Acute renal failure has been reported through post-marketing surveillance in patients receiving parecoxib (see section 4.8).
Slovenian: Med študijami v obdobju trženja so pri bolnikih, ki so prejemali parekoksib, poročali o akutni odpovedi ledvic (glejte poglavje 4.8).
English: Opioid-sparing effects
Slovenian: Učinek manjše uporabe opioidov
English: Of the patients treated with placebo, 270 patients received placebo for up to 4 days, 43 patients for up to 5 days, while only 3 patients were treated for up to 6 days and 2 patients for 7 or more days.
Slovenian: 43 bolnikov do 5 dni, le 3 bolnike pa so zdravili do 6 dni in 2 bolnika 7 dni ali več.
English: Dynastat contains the active substance parecoxib.
Slovenian: Zdravilo Dynastat vsebuje učinkovino parekoksib.
English: It is not recommended to inject into an IV line delivering glucose 50 mg/ml (5%) in RingerLactate solution for injection, or other IV fluids not listed in this section, as this may cause precipitation from solution.
Slovenian: Ni priporočljivo, da bi zdravilo injicirali v intravensko pot, po kateri teče 50 mg/ml (5 %) glukoza v raztopini Ringerjevega laktata za injiciranje ali kakršnakoli druga intravenska tekočina, ki ni navedena v tem poglavju, ker to lahko povzroči precipitacijo iz raztopine.