FrancophonIA/ELRC3.0 huggingface dataset:
English: If your female partner is not pregnant now but is of childbearing age, she must be tested for pregnancy each month during treatment and for 7 months after treatment has stopped.
Croatian: Ako Vaša partnerica nije trudna, ali je u reproduktivnoj dobi, mora napraviti test na trudnoću svaki mjesec za vrijeme Vašeg liječenja te tijekom 7 mjeseci nakon prestanka liječenja.
English: Ribavirin Teva is available in different pack sizes containing 84, 112, 140 or 168 capsules to be swallowed.
Croatian: Ribavirin Teva dostupan je u pakiranjima različite veličine koja sadrže 84, 112, 140 ili 168 kapsula za primjenu kroz usta.
English: EU/1/09/509/001 (84 capsules) EU/1/09/509/002 (112 capsules) EU/1/09/509/003 (140 capsules) EU/1/09/509/004 (168 capsules)
Croatian: EU/1/09/509/001 (84 kapsule) EU/1/09/509/002 (112 kapsula) EU/1/09/509/003 (140 kapsula) EU/1/09/509/004 (168 kapsula)
English: EU/1/09/509/001 - 84 capsules EU/1/09/509/002 - 112 capsules EU/1/09/509/003 - 140 capsules EU/1/09/509/004 - 168 capsules
Croatian: EU/1/09/509/001 - 84 kapsule EU/1/09/509/002 - 112 kapsula EU/1/09/509/003 - 140 kapsula
English: Anti-thyroid antibody positive
Croatian: pozitivna antitiroidna protutijela
English: The pharmacokinetics of ribavirin and interferon alfa-2b (dose-normalized) is similar in adults and children or adolescents.
Croatian: Farmakokinetika lijeka ribavirin i interferona alfa-2b (normalizirana po dozi) slična je u odraslih i djece ili adolescenata.
English: Do not use this medicine after the expiry date which is stated on the outer packaging.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na vanjskom pakiranju iza oznake "EXP".
English: For children or adolescents who cannot swallow a hard capsule, an oral solution of ribavirin is available.
Croatian: Za djecu ili adolescente koji ne mogu progutati tvrdu kapsulu, ribavirin je dostupan u obliku oralne otopine.
English: This decline was significant among responders (0.3 for Metavir and -1.2 for Ishak) and stable (-0.1 for Metavir and -0.2 for Ishak) among nonresponders.
Croatian: To je smanjenje bilo značajno u bolesnika koji su odgovorili na liječenje (-0,3 za Metavir te -1,2 za Ishak) te stabilno (-0,1 za Metavir te -0,2 za Ishak) u bolesnika bez odgovora.
English: Genotype 1 > 600,000 IU/mL
Croatian: Genotip 1> 600 000 IU/ml svi
English: If you forget to take Ribavirin Teva
Croatian: Ako ste zaboravili uzeti Ribavirin Teva
English: Due to the lack of data in these two multicentre trials for children with severe progression of the disease, and the potential for undesirable effects, the benefit/risk of the combination of ribavirin and interferon alfa-2b needs to be carefully considered in this population (see sections 4.1, 4.4 and 4.8).
Croatian: Zbog nedostatka podataka u ta dva multicentrična ispitivanja za djecu s teškom progresijom bolesti i zbog mogućeg razvoja nuspojava, u ovoj je populaciji potrebno je pažljivo analizirati odnos koristi i rizika kombiniranog liječenja ribavirinom i interferonom alfa-2b (vidjeti dijelove 4.1, 4.4 i 4.8).
English: Enuresis, micturition disorder, urinary incontinence, proteinuria
Croatian: enureza, poremećaj mokrenja, urinarna inkontinencija, proteinurija
English: If the child is weighing less than 47 kg or unable to swallow capsules an oral solution of ribavirin should be used.
Croatian: Ako dijete teži manje od 47 kg ili ako ne može gutati kapsule, dostupna je i oralna otopina ribavirina.
English: - This medicine has been prescribed for you only Do not pass it on to others.
Croatian: - Ovaj je lijek propisan samo Vama.
English: If an acute hypersensitivity reaction (e.g., urticaria, angioedema, bronchoconstriction, anaphylaxis) develops, Ribavirin Teva must be discontinued immediately and appropriate medical therapy instituted.
Croatian: Ako se razvije akutna reakcija preosjetljivosti (npr. urtikarija, angioedem, bronhokonstrikcija, anafilaksija), odmah se mora prekinuti davanje lijeka Ribavirin Teva i započeti odgovarajuće liječenje.
English: Although ribavirin has no direct cardiovascular effects, anaemia associated with ribavirin may result in deterioration of cardiac function, or exacerbation of the symptoms of coronary disease, or both.
Croatian: Iako ribavirin nema izravnih kardiovaskularnih učinaka, anemija povezana s ribavirinom može dovesti do slabljenja srčane funkcije ili egzacerbacije simptoma koronarne bolesti, ili oboje.
English: There were some cases of more severe neutropenia in patients treated with ribavirin in combination with peginterferon alfa-2b (WHO grade 3: 39 of 186 [21 %]; and WHO grade 4: 13 of 186 [7 %]); WHO grade 3 leukopenia was also reported in 7 % of this treatment group.
Croatian: Bilo je slučajeva teže neutropenije u bolesnika liječenih ribavirinom u kombinaciji s peginterferonom alfa-2b (SZO stupanj 3: 39 od 186 [21%] bolesnika; i SZO stupanj 4: 13 od 186 bolesnika [7%]); leukopenija SZO stupnja 3 također je prijavljena u 7% bolesnika u ovoj terapijskoj skupini.
English: Pancytopenia: Ribavirin Teva can cause a decrease in your platelet and red and white blood cell count when used in combination with peginterferon.
Croatian: Pancitopenija: Ribavirin Teva može uzrokovati smanjenje broja krvnih pločica, crvenih i bijelih krvnih stanica kada se koristi u kombinaciji s peginterferonom.
English: For children and adolescents weighing less than 47 kg a solution formulation is available.
Croatian: Za djecu i adolescente težine manje od 47 kg ovaj je lijek dostupan u obliku otopine.
English: If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Croatian: U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka, upitajte svog liječnika ili ljekarnika.
English: The sustained response at the end of follow-up was significantly increased by the addition of ribavirin to interferon alfa-2b (41 % vs 16 %, p < 0.001).
Croatian: Trajan odgovor na liječenje na kraju razdoblja praćenja značajno se povećao dodavanjem lijeka ribavirin interferonu alfa-2b (41% u odnosu na 16%, p < 0,001).
English: Pharmacotherapeutic group: Antivirals for systemic use, nucleosides and nucleotides excl. reverse transcriptase inhibitors, ATC code: J05AB04.
Croatian: Farmakoterapijska skupina: pripravci za liječenje sustavnih virusnih infekcija, nukleozidi i nukleotidi (isključujući inhibitore reverzne transkriptaze, ATK oznaka J05AB04.
English: Ribavirin Teva contains the active substance ribavirin.
Croatian: Ribavirin Teva sadrži djelatnu tvar ribavirin.
English: Patients whose dose of Ribavirin Teva is reduced to 600 mg daily receive one 200 mg capsule in the morning and two 200 mg capsules in the evening.
Croatian: Bolesnici kojima je doza lijeka Ribavirin Teva smanjena na dnevnu dozu od 600 mg uzimaju jednu kapsulu od 200 mg ujutro i dvije kapsule od 200 mg navečer.
English: Based on published data, single-dose ribavirin pharmacokinetics was altered (increased AUCtf and Cmax) in patients with renal dysfunction compared with control subjects (creatinine clearance > 90 mL/minute).
Croatian: Prema objavljenim podacima farmakokinetika ribavirina nakon jedne doze bila je izmijenjena (povećani AUCtf i Cmax) u bolesnika s oštećenom funkcijom bubrega u usporedbi s kontrolnim ispitanicima (klirens kreatinina >90 ml/min).
English: Most of the changes in laboratory values in the ribavirin/peginterferon alfa-2b clinical trial were mild or moderate.
Croatian: Promjene u laboratorijskim vrijednostima u kliničkom ispitivanju lijeka ribavirin/peginterferona alfa-2b bile su većinom blage ili umjerene.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer Carton 84, 112, 140, 168 hard capsules
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Vanjsko pakiranje 84, 112, 140, 168 tvrdih kapsula
English: 3 capsulesa
Croatian: 3 kapsulea
English: In those patients that received > 10.6 mg/kg ribavirin (800 mg dose in typical 75 kg patient), regardless of genotype or viral load, response rates were significantly higher than in those patients that received ≤ 10.6 mg/kg ribavirin (Table 7), while response rates in patients that received > 13.2 mg/kg ribavirin were even higher.
Croatian: U bolesnika koji su primali >10,6 mg/kg lijeka ribavirin (doza od 800 mg u bolesnika tjelesne težine 75 kg) je, bez obzira na genotip ili virusno opterećenje, stope odgovora bile značajno veće nego u onih koji su primali ≤10,6 mg/kg lijeka ribavirin (Tablica 7), dok je stopa odgovora u bolesnika koji su primali >13,2 mg/kg lijeka ribavirin bila još i veća.
English: When deciding not to defer treatment until adulthood, it is important to consider that the combination therapy induced a growth inhibition that may be irreversible in some patients.
Croatian: Prilikom donošenja odluke o tome da se liječenje neće odgoditi do odrasle dobi, važno je uzeti u obzir da je kombinacijska terapija dovela do inhibicije rasta, koji u nekih bolesnika može biti ireverzibilan.
English: Paediatric population: No data are available in children below 3 years of age.
Croatian: Nema podataka o primjeni u djece u dobi do 3 godine.
English: In clinical trials of 118 children and adolescents 3 to 16 years of age treated with combination therapy of interferon alfa-2b and ribavirin, 6 % discontinued therapy due to adverse events.
Croatian: U kliničkim ispitivanjima sa 118 djece i adolescenata dobi od 3 do 16 godina koji su liječeni kombiniranom terapijom interferona alfa-2b i lijeka ribavirin, 6% bolesnika prekinulo je liječenje zbog nuspojava.
English: Method of administration Ribavirin capsules should be administered orally with food.
Croatian: Način primjene Ribavirin kapsule primjenjuju se peroralno uz obrok.
English: The concomitant use of ribavirin with zidovudine is not recommended due to an increased risk of anaemia (see section 4.4).
Croatian: Ne preporučuje se istodobna primjena ribavirina i zidovudina zbog povećanog rizika za razvoj anemije (vidjeti dio 4.4).
English: - have any blood disorder, such as anaemia (low blood count), thalassemia or sickle-cell anaemia
Croatian: - ako imate bilo kakav poremećaj krvi, kao što su anemija (smanjen broj krvnih zrnaca), talasemija ili anemija srpastih stanica
English: Extreme care must be taken to avoid pregnancy in partners of male patients taking ribavirin (see sections 4.3, 4.4 and 5.3).
Croatian: Potrebno je strogo paziti da se izbjegne trudnoća u žena čiji partneri uzimaju ribavirin (vidjeti dijelove 4.3, 4.4 i 5.3).
English: In females of childbearing potential, Ribavirin must not be initiated until a report of a negative pregnancy test has been obtained immediately prior to initiation of therapy.
Croatian: U žena reproduktivne dobi liječenje ribavirinom ne smije se započeti dok se ne dobije negativan rezultat testa na trudnoću neposredno prije početka liječenja.
English: Co-infected patients receiving both antiretroviral (ARV) and anti-hepatitis treatment should be closely monitored, assessing their Child-Pugh score during treatment.
Croatian: Bolesnike s istodobnom infekcijom koji primaju i antiretrovirusne lijekove i terapiju za liječenje hepatitisa treba pažljivo nadzirati te im tijekom liječenja procijenjivati Child-Pugh status.
English: Genotype 1 ≤ 600,000
Croatian: Genotip 1≤ 600 000 IU/ml svi
English: Co-administration of ribavirin and didanosine is not recommended.
Croatian: Ne preporučuje se istodobna primjena lijeka ribavirin i didanozina.
English: For patients receiving a 800 mg (< 65 kg) - 1,000 mg (65-80 kg) - 1,200 mg (81-105 kg) or 1,400 mg (> 105 kg) dose, 1st dose reduction of Ribavirin Teva is by 200 mg/day (except in patients receiving the 1,400 mg, dose reduction should be by 400 mg/day).
Croatian: U bolesnika koji primaju dozu od 800 mg (<65 kg), 1000 mg (65-80 kg), 1200 mg (81-105 kg) ili 1400 mg (>105 kg), prvo smanjenje doze lijeka Ribavirin Teva je za 200 mg/dan (osim u bolesnika koji primaju 1400 mg, u kojih dozu treba smanjiti za 400 mg/dan).
English: All Genotype
Croatian: Svi Genotip
English: Standard haematologic tests,blood chemistries (complete blood count [CBC] and differential, platelet count, electrolytes, serum creatinine, liver function tests, uric acid) and pregnancy tests must be conducted in all patients prior to initiating therapy.
Croatian: U svih se bolesnika prije početka liječenja moraju provesti standardne hematološke i biokemijske pretrage (kompletna krvna slika [KKS], diferencijalna krvna slika, broj trombocita, elektroliti, serumski kreatinin, testovi funkcije jetre, uratna kiselina) te testovi na trudnoću.
English: The use of ribavirin in combination with peginterferon alfa-2b had no observable negative impact on the control of HIV viraemia during therapy or follow-up.
Croatian: Primjena lijeka ribavirin u kombinaciji s peginterferonom alfa-2b nije imala vidljivih negativnih učinaka na kontrolu viremije HIV-a tijekom liječenja ili naknadnog praćenja bolesnika.
English: Multiple-dose pharmacokinetic properties for ribavirin capsules and interferon alfa-2b in children and adolescents with chronic hepatitis C between 5 and 16 years of age are summarized in Table 10.
Croatian: Farmakokinetička svojstva ribavirin kapsula i interferona alfa-2b nakon primjene višestrukih doza u djece i adolescenata s kroničnim hepatitisom C u dobi između 5 i 16 godina prikazana su u Tablici 10.
English: Anaemia (haemoglobin < 9.4 g/dL) was reported in 12 % (23/194) of patients treated with ribavirin in combination with peginterferon alfa-2b.
Croatian: Anemija (hemoglobin <9,4 g/dl) je prijavljena u 12% (23/194) bolesnika liječenih ribavirinom u kombinaciji s peginterferonom alfa-2b.
English: Children and adolescents 3 to 16 years of age with compensated chronic hepatitis C and detectable HCV-RNA (assessed by a central laboratory using a research-based RT-PCR assay) were enrolled in two multicentre trials and received ribavirin 15 mg/kg per day plus interferon alfa-2b 3 MIU/m times a week for 1 year followed by 6 months follow-up after treatment.
Croatian: Djeca i adolescenti u dobi od 3 do 16 godina s kompenziranim kroničnim hepatitisom C i mjerljivom razinom HCV-RNK (procijenio centralni laboratorij korištenjem istraživanja zasnovanog na RT-PCR testu) uključeni su u multicentrično ispitivanje i liječeni ribavirinom u dozi od 15 mg/kg na dan i interferonom alfa-2b u dozi od 3 MIU/m2 3 puta na tjedan tijekom 1 godine, nakon čega su praćeni 6
English: CD4 lymphocytes decrease:
Croatian: Smanjenje broja CD4 limfocita:
English: In a clinical trial with 107 children and adolescent patients (3 to 17 years of age) treated with combination therapy of peginterferon alfa-2b and ribavirin, dose modifications were required in 25 % of patients, most commonly for anaemia, neutropenia and weight loss.
Croatian: U kliničkom ispitivanju sa 107 djece i adolescenata (3 do 17 godina) liječenih kombiniranom terapijom peginterferona alfa-2b i lijeka ribavirin bilo je potrebno prilagoditi dozu u 25% bolesnika, najčešće zbog anemije, neutropenije i gubitka tjelesne težine.
English: The Kaplan-Meier estimate for continued sustained response over 5 years is 97 % (95 % CI: 95-99 %) for patients receiving nonpegylated interferon alfa-2b (with or without ribavirin), and is 99 % (95 % CI: 98-100 %) for patients receiving pegylated interferon alfa-2b (with or without ribavirin).
Croatian: Kaplan-Meierova procjena održivosti trajnog virološkog odgovora tijekom 5 godina iznosi 97% (uz 95% CI: 95-99%) za bolesnike koji su dobivali nepegilirani interferon alfa-2b (sa ili bez lijeka ribavirin) odnosno 99% (uz 95% CI: 98-100%) za bolesnike koji su dobivali pegilirani interferon alfa-2b (sa ili bez lijeka ribavirin).
English: − severe rashes which may be associated with blisters in the mouth, nose, eyes and other mucosal membranes (erythema multiforme, Stevens Johnson syndrome), toxic epidermal necrolysis
Croatian: upalu gušterače, teške osipe koji mogu biti popraćeni mjehurima u ustima, nosu, očima i drugim sluznicama (multiformni eritem, Stevens-Johnsonov sindrom), toksičnu epidermalnu nekrolizu (mjehurići i ljuštenje gornjeg sloja kože).
English: * Number (%) of patients a. Defined as HCV-RNA below limit of detection using a research based RT-PCR assay at end of treatment and during follow-up period
Croatian: Definira se kao HCV-RNK ispod granice detekcije korištenjem istraživanja koje se zasniva na RT-PCR testu na kraju liječenja i tijekom razdoblja praćenja
English: Ribavirin Teva is indicated for the treatment of chronic hepatitis C virus (HCV) infection in adults, children 3 years of age and older and adolescents and must only be used as part of a combination regimen with interferon alfa-2b.
Croatian: Ribavirin Teva indiciran je u liječenju kronične infekcije virusom hepatitisa C (HCV) u odraslih, djece u dobi od 3 godine i starije te adolescenata, a smije se primjenjivati samo u kombinaciji s interferonom alfa-2b.
English: The combination of Ribavirin Teva with interferon alfa-2b is used to treat patients 3 years of age and older who have chronic hepatitis C (HCV) infection.
Croatian: Kombinacija Ribavirina Teva s interferonom alfa-2b primjenjuje se za liječenje bolesnika u dobi od 3 godine i starijih koji boluju od kronične infekcije hepatitisom C (HCV).
English: In this trial, the combination of ribavirin and peginterferon alfa-2b (1.5 micrograms/kg/week) was significantly more effective than the combination of ribavirin and interferon alfa-2b, particularly in patients infected with Genotype 1.
Croatian: U ovom je ispitivanju kombinacija lijeka ribavirin i peginterferona alfa-2b (1,5 mikrograma/kg/tjedan) bila značajno djelotvornija od kombinacije lijeka ribavirin i interferona alfa-2b, osobito u bolesnika inficiranih genotipom
English: There is no safety or efficacy information on the use of Ribavirin with other forms of interferon (i.e. not alfa-2b).
Croatian: Nema podataka o sigurnosti i djelotvornosti Ribavirina primijenjenog s drugim oblicima interferona (npr. koji nisu alfa-2b).
English: The safety of ribavirin capsules is evaluated from data from four clinical trials in patients with no previous exposure to interferon (interferon-naïve patients): two trials studied ribavirin in combination with interferon alfa-2b, two trials studied ribavirin in combination with peginterferon alfa-2b.
Croatian: Sigurnost ribavirin kapsula procijenjena je na temelju podataka prikupljenih u četiri klinička ispitivanja u bolesnika koji prethodno nisu bili liječeni interferonom: u dva ispitivanja proučavao se ribavirin u kombinaciji s interferonom alfa-2b, a u preostala dva ispitivanja u kombinaciji s peginterferonom alfa-2b.
English: The other ingredients are calcium hydrogen phosphate, croscarmellose sodium, povidone, magnesium stearate.
Croatian: Drugi sastojci su: kalcijev hidrogenfosfat, umrežena karmelozanatij, povidon, magnezijev stearat.
English: All Genotypes
Croatian: Svi genotipovi svi
English: Ribavirin 15 mg/kg/day interferon alfa-2b 3 MIU/m2 3 times a week
Croatian: Ribavirin 15 mg/kg/dan interferon alfa-2b 3 MIU/m2 3 puta na tjedan
English: − stroke (cerebrovascular events).
Croatian: samoubojstvo, moždani udar (cerebrovaskularni događaji).
English: Table 7 Sustained response rates with ribavirin + peginterferon alfa-2b (by ribavirin dose [mg/kg], genotype and viral load)
Croatian: Tablica 7 Stopa trajnog odgovora kod liječenja kombinacijom ribavirin + peginterferon alfa-2b (prema dozi lijeka ribavirin [mg/kg], genotipu i virusnom opterećenju)
English: Carrat F, Bani-Sadr F, Pol S et al. JAMA 2004; 292(23):
Croatian: 1Carrat F, Bani-Sadr F, Pol S et al.
English: 2 capsules in the morning and 2 capsules in the evening See adult dose
Croatian: 2 kapsule ujutro i 2 kapsule navečer
English: Dose modification for adults
Croatian: Vidjeti dozu za odrasle
English: Hyperthyroidism, virilism
Croatian: hipertireoza, virilizam
English: Chest pain, oedema, pain, feeling cold
Croatian: bol u prsištu, edem, bol, osjećaj hladnoće
English: Ribavirin Teva 200 mg hard capsules
Croatian: Ribavirin Teva 200 mg tvrde kapsule
English: Paediatric patients (children 3 years of age and older and adolescents): Ribavirin Teva is indicated, in a combination regimen with interferon alfa2b, for the treatment of children and adolescents 3 years of age and older, who have all types of chronic hepatitis C except genotype 1, not previously treated, without liver decompensation, and who are positive for HCV-RNA.
Croatian: Pedijatrijski bolesnici (djeca u dobi od 3 godine i više te adolescenti): Ribavirin Teva je u kombinaciji s interferonom alfa2b indiciran za liječenje djece i adolescenata u dobi od 3 godine i starijih koja imaju sve vrste kroničnog hepatitisa C, osim genotipa 1, koja prethodno nisu liječena, koja nemaju dekompenzaciju jetre i koja su pozitivna na HCV-RNK.
English: > 4 mg/dL (adults) * For patients receiving a 1,000 mg (< 75 kg) or 1,200 mg (> 75 kg) dose, ribavirin dose should be reduced to 600 mg/day (administered as one 200 mg capsule in the morning and two 200 mg capsules in the evening).
Croatian: *U bolesnika koji primaju dozu od 1000 mg (<75 kg) ili 1200 mg (>75 kg), dozu ribavirina treba smanjiti na 600 mg/dan (primjenjenu kao jedna kapsula od 200 mg ujutro i dvije kapsule od 200 mg navečer).
English: The use of ribavirin in combination treatment with interferon alfa-2b was evaluated in a number of clinical trials.
Croatian: Primjena lijeka ribavirin u kombinaciji s interferonom alfa-2b ocjenjivala se u nekoliko kliničkih ispitivanja.
English: Oral formulations of ribavirin monotherapy have been investigated as therapy for chronic hepatitis C in several clinical trials.
Croatian: Peroralni oblici lijeka ribavirin ispitivani su u nekoliko kliničkih ispitivanja kao monoterapija za kronični hepatitis C.
English: Genotype 2/3/4 (n=26)
Croatian: Cjelokupni odgovora (n=118) Genotip 1 (n=92) Genotip 2/3/4 (n=26)
English: No pharmacokinetic interactions were noted between ribavirin and peginterferon alfa-2b or interferon alfa-2b in a multiple-dose pharmacokinetic study.
Croatian: Nisu primijećene farmakokinetičke interakcije između lijeka ribavirin i peginterferona alfa-2b ili interferona alfa-2b u farmakokinetičkom ispitivanju s primjenom višestrukih doza.
English: Ribavirin must not be used by females who are pregnant (see sections 4.3, 4.4 and 5.3).
Croatian: Trudnice ne smiju uzimati ribavirin (vidjeti dijelove 4.3, 4.4 i 5.3).
English: Ribavirin Teva dose based on body weight when used in combination with interferon alfa-2b or peginterferon alfa-2b in children above 3 years of age and adolescents
Croatian: Doza lijeka Ribavirin Teva određena na temelju tjelesne težine kad se kombinira s interferonom alfa-2b ili peginterferonom alfa-2b u djece starije od 3 godine i adolescenata Tjelesna težina djeteta/
English: Ribavirin has been shown to produce high inter- and intra-subject pharmacokinetic variability following single oral doses (intrasubject variability of approximately 30 % for both AUC and Cmax), which may be due to extensive first pass metabolism and transfer within and beyond the blood compartment.
Croatian: Ribavirin iskazuje veliku interindividualnu i intraindividualnu farmakokinetičku varijabilnost nakon primjene jedne peroralne doze (intraindividualna varijabilnost iznosi približno 30% i za AUC i za
English: Teva Denmark A.S. Tlf: +45 44 98 55 11
Croatian: Tlf: +45 44 98 55 11
English: All
Croatian: svi
English: White, opaque and imprinted with blue ink.
Croatian: Tvrda kapsula Bijela, neprozirna s oznakama otisnutima plavom bojom.
English: Patients progressing to hepatic decompensation should have their anti-hepatitis treatment immediately discontinued and the ARVtreatment reassessed.
Croatian: U bolesnika u kojih se razvija dekompenzacija jetre mora se odmah prekinuti primjena lijekova protiv hepatitisa te ponovno razmotriti primjerenost antiretrovirusne terapije.