FrancophonIA/ELRC3.0 huggingface dataset:
English: There were a few cases of subjects with delayed elimination.
Slovenian: V nekaj primerih je bil čas izločanja podaljšan.
English: After reconstitution, or reconstitution and dilution, chemical and physical in use stability has been demonstrated for 12 hours at 25 °C.
Slovenian: Po rekonstituciji, ali rekonstituciji in razredčitvi je bila dokazana 12-urna kemična in fizikalna stabilnost za uporabo pri 25 ° C.
English: If prescribed more than two tablets a day, the tablets should be taken twice daily.
Slovenian: Če imate predpisano več kot 2 tableti na dan, je treba vzeti tablete dvakrat na dan.
English: Your doctor will tell you how long to continue taking the medicine.
Slovenian: Vaš zdravnik vam bo povedal, kako dolgo boste še jemali to zdravilo.
English: Atazanavir (used to treat HIV-infection).
Slovenian: - atazanavir (ki se uporablja za zdravljenje okužbe s HIV).
English: Note: This SPC, labelling and packages leaflet is the version valid at the time of Commission Decision.
Slovenian: Opomba: Ta povzetek glavnih značilnosti zdravila, označevanje in navodilo za uporabo so različice veljavne ob izdaji odločbe Komisije.
English: Protium is available in the following pack sizes:
Slovenian: Zdravilo Protium je na voljo v naslednjih velikostih pakiranja:
English: Gastrointestinal infections caused by bacteria
Slovenian: Okužbe prebavil povzročene z bakterijami
English: If your stomach acid level needs to be controlled rapidly, a starting dose of 160 mg (four vials) should be enough to lower the amount of stomach acid sufficiently.
Slovenian: Če je potrebno hitro zmanjšanje želodčne kisline, mora biti začetni odmerek 160 mg (4 viale) dovolj, da ustrezno zmanjša količino želodčne kisline.
English: The main metabolite in both the serum and urine is desmethylpantoprazole which is conjugated with sulphate.
Slovenian: Glavni presnovek v serumu in v urinu je desmetilpantoprazol, ki je konjugiran s sulfatom.
English: EXP Shelf life after reconstitution: 12 hours
Slovenian: EXP Rok uporabnosti po rekonstituciji: 12 ur
English: These tablets are not recommended for use in children below 12 years.
Slovenian: Uporaba teh tablet pri otrocih mlajših od 12 let ni priporočljiva.
English: If the patient is allergic to peanut or soya, do not use this medicinal product (see section 4.3).
Slovenian: Če je bolnik alergičen na arašide ali sojo, naj ne uporablja tega zdravila (glejte poglavje 4.3).
English: In these individuals the metabolism of pantoprazole is probably mainly catalysed by CYP3A4.
Slovenian: Pri teh posameznikih se metabolizem pantoprazola verjetno katalizira predvsem prek CYP3A4.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 12 hours, at no more than 25 °C.
Slovenian: Če ni takoj uporabljena, so čas in pogoji shranjevanja pred uporabo odgovornost uporabnika in naj normalno ne presežejo 12 ur in 25ºC.
English: The table below lists adverse reactions reported with pantoprazole, ranked under the following frequency classification:
Slovenian: Spodnja tabela navaja poročane neželene učinke pantoprazola razvrščene po naslednji klasifikaciji pogostnosti:
English: If the combination of atazanavir with a proton pump inhibitor is judged unavoidable, close clinical monitoring (e.g virus load) is recommended in combination with an increase in the dose of atazanavir to 400 mg with 100 mg of ritonavir.
Slovenian: Če je po presoji kombinacija atazanavirja z zaviralcem protonske črpalke neizogibna, se priporoča skrbno klinično spremljanje (npr. virusna obremenitev) v kombinaciji s povečanjem odmerka atazanavirja na 400 mg s 100 mg ritonavirja.
English: Tablets should not be chewed or crushed, and should be swallowed whole 1 hour before a meal with some water.
Slovenian: Tablete se ne smejo žvečiti ali zdrobiti, treba jih je pogoltniti cele z nekaj vode 1 uro pred obrokom.
English: Not known (frequency cannot be estimated from the available data) Hallucination, confusion (especially in patients with a history of these symptoms); decreased sodium level in blood.
Slovenian: - Neznana (ni mogoče oceniti iz razpoložljivih podatkov) halucinacije, zmedenost (zlasti pri bolnikih, ki so te bolezenske znake že imeli); zmanjšanje ravni natrija v krvi.
English: Swallow whole, do not chew.
Slovenian: Pogoltnite celo, ne žvečite.
English: Excretion into human milk has been reported.
Slovenian: Poročali so o izločanju v materino mleko pri človeku.
English: If a 2-week period of treatment is not sufficient, healing will be achieved in almost all cases within a further 2 weeks.
Slovenian: Če dvotedensko zdravljenje ne zadošča, dosežemo ozdravitev v večini primerov v naslednjih 2 tednih.
English: Stevens-Johnson syndrome; Lyell syndrome;
Slovenian: Stevens-Johnson sindrom;
English: In the case of combination therapy, the summaries of product characteristics of the respective medicinal products should be observed.
Slovenian: Kombinirano zdravljenje Pri kombiniranem zdravljenju je treba upoštevati povzetke glavnih značilnosti predpisanih zdravil.
English: The recommended starting dose is usually two tablets a day.
Slovenian: Priporočen začetni odmerek je običajno 2 tableti na dan.
English: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Slovenian: zelo pogosti (≥1/10); pogosti (≥1/100 do <1/10); občasni (≥1/1.000 do <1/100); redki (≥1/10.000 do <1/1.000); zelo redki (<1/10.000); neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: If you forget to take Protium
Slovenian: Če ste pozabili vzeti zdravilo Protium
English: Protium injections may influence the effectiveness of other medicines, so tell your doctor if you are taking
Slovenian: Zdravilo Protium lahko vpliva na učinkovitost drugih zdravil, zato povejte svojemu zdravniku, če jemljete:
English: Very Rare (affects less than 1 user in 10,000) a reduction in the number of blood platelets, which may cause you to bleed or bruise more than normal; a reduction in the number of white blood cells, which may lead to more frequent infections.
Slovenian: - Zelo redki (pojavijo se pri manj kot 1 od 10.000 bolnikov) zmanjšanje števila krvnih ploščic, kar lahko privede do pogostejših krvavitev ali modric, kot je običajno; zmanjšanje števila belih krvnih celic, kar lahko privede do pogostejših okužb.
English: In animal reproduction studies, signs of slight fetotoxicity were observed at doses above 5 mg/kg.
Slovenian: V reproduktivnih raziskavah na živalih so pri odmerkih nad 5mg/kg opazili znake rahle toksičnosti za plod.
English: Sweden United Kingdom
Slovenian: Švedska Velika Britanija
English: Systemic exposure with up to 240 mg administered intravenously over 2 minutes were well tolerated.
Slovenian: Sistemsko izpostavljenost z odmerki do 240 mg dani intravensko v 2 minutah, so preiskovanci dobro prenašali.
English: Therefore, Protium 40 mg powder for solution for injection is not recommended for use in patients below 18 years of age until further data become available.
Slovenian: Zato uporaba Protium 40 mg praška za raztopino za injiciranje pri otrocih pod 18 let ni priporočljiva, dokler ne bo na voljo nadaljnjih podatkov.
English: Glass or plastic containers should be used for dilution.
Slovenian: Za redčenje je treba uporabiti steklene ali plastične vsebnike.
English: Each gastro-resistant tablet contains 1.06 microgram soya oil.
Slovenian: Ena gastrorezistentna tableta vsebuje 1,06 mikrogramov sojinega olja.
English: Two vials (80 mg pantoprazole) a day.
Slovenian: 2 viali (80 mg pantoprazola) na dan.
English: Like all medicines, Protium can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi zdravilo Protium neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: Special patient groups: - If you have kidney problems, moderate or severe liver problems, you should not take Protium for eradication of Helicobacter pylori.
Slovenian: Posebne skupine bolnikov: - Če imate težave z ledvicami, zmerne ali hude težave z jetri ne smete jemati zdravila Protium za zdravljenje infekcije z bakterijo Helicobacter pylori.
English: SPECIAL STORAGE CONDITIONS Do not store above 25 °C.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Shranjujte pri temperaturi do 25º C.
English: However, according to the studies conducted so far, the formation of carcinoid precursors (atypical hyperplasia) or gastric carcinoids as were found in animal experiments (see section 5.3) have not been observed in humans.
Slovenian: V dosedanjih študijah na ljudeh ni nikoli prišlo do tvorbe karcinoidnih predstopenj (atipična hiperplazija) ali želodčnih karcinoidov, kot so jih našli pri poskusih na živalih (glejte poglavje 5.3).
English: Results from a range of interaction studies demonstrate that pantoprazole does not effect the metabolism of active substances metabolised by CYP1A2 (such as caffeine, theophylline), CYP2C9 (such as piroxicam, diclofenac, naproxen), CYP2D6 (such as metoprolol), CYP2E1 (such as ethanol) or does not interfere with p-glycoprotein related absorption of digoxin.
Slovenian: Rezultati iz različnih študij medsebojnega delovanja so pokazali, da pantoprazol ne vpliva na presnovo učinkovin, ki se presnavljajo s CYP1A2 (kot kofein, teofilin), CYP2C9 (kot piroksikam, diklofenak, naproksen), CYP2D6 (kot metoprolol), CYP2E1 (kot etanol) ali ne moti s p-glikoproteinom povezano absorbcijo digoksina.
English: The substance is almost exclusively metabolized in the liver.
Slovenian: Učinkovina se presnavlja skoraj izključno v jetrih.
English: In the case of a rise of liver enzymes the treatment should be stopped.
Slovenian: V primeru povišanja jetrnih encimov je treba zdravljenje prekiniti.
English: Mean peak plasma concentrations were increased by about 60 %.
Slovenian: Povprečne vrednosti maksimalnih koncentracij v plazmi so se povečale za približno 60 %.
English: 4.6 Pregnancy and lactation Pregnancy
Slovenian: 4.6 Nosečnost in dojenje
English: EXP Shelf life after reconstitution (and dilution): 12 hours
Slovenian: EXP Rok uporabnosti po rekonstituciji (in redčenju): 12 ur
English: There were no interactions with concomitantly administered antacids.
Slovenian: Medsebojnega delovanja ob sočasnem jemanju antacidov ni bilo.
English: Following administration of single oral doses of 20 or 40 mg pantoprazole to children aged 5 - 16 years AUC and Cmax were in the range of corresponding values in adults.
Slovenian: Po enkratnih peroralnih odmerkih 20 mg ali 40 mg pantoprazola pri otrocih v starosti 5-16 let sta bila AUC in Cmax v območju vrednosti, ki ustreza vrednostim odraslih.
English: As with other proton pump inhibitors and H2 receptor inhibitors, treatment with pantoprazole reduces acidity in the stomach and thereby increases gastrin in proportion to the reduction in acidity.
Slovenian: Kot pri ostalih zaviralcih protonske črpalke in zaviralcih receptorjev H2 zdravljenje s pantoprazolom zmanjša kislost v želodcu in zato zviša gastrin sorazmerno znižanju kislosti.
English: Ask your doctor or pharmacist for advice before taking any medicine.
Slovenian: Posvetujte se z zdravnikom ali s farmacevtom preden vzamete katerokoli zdravilo.
English: The usual dose is one tablet a day.
Slovenian: Običajen odmerek je 1 tableta na dan.
English: Pantoprazole, like all proton pump inhibitors (PPIs), might be expected to increase the counts of bacteria normally present in the upper gastrointestinal tract.
Slovenian: Pri pantoprazolu kot pri vseh zaviralcih protonske črpalke (ZPČ) se lahko pričakuje povečanje števila bakterij, ki so normalno prisotne v zgornjem delu prebavnega trakta.
English: - If you are taking a medicine containing atazanavir (for the treatment of HIV-infection) at the same time as pantoprazole, ask your doctor for specific advise.
Slovenian: - če jemljete istočasno s pantoprazolom zdravilo, ki vsebuje atazanavir (za zdravljenje okužbe s HIV), se posvetujte s svojim zdravnikom
English: - Warfarin and phenprocoumon, which affect the thickening, or thinning of the blood.
Slovenian: - varfarin in fenprokumon, ki vplivata na zgoščevanje oziroma redčenje krvi.
English: Each vial contains 1 mg disodium edetate and 0.24 mg sodium hydroxide.
Slovenian: Ena viala vsebuje 1 mg dinatrijevega edetata in 0,24 mg natrijevega hidroksida.
English: In the case of a rise of the liver enzymes, the treatment should be discontinued (see section 4.2).
Slovenian: V primeru povišanja jetrnih encimov je treba zdravljenje prekiniti (glejte poglavje 4.2).
English: Your nurse or your doctor will administer the daily dose to you as an injection into a vein over a period of 2 - 15 minutes.
Slovenian: Injiciranje dnevnega odmerka, ki vam ga bo dala medicinska sestra ali vaš zdravnik v veno, bo trajalo 2-15 minut.
English: Coumarin anticoagulants (phenprocoumon or warfarin) Although no interaction during concomitant administration of phenprocoumon or warfarin has been observed in clinical pharmacokinetic studies, a few isolated cases of changes in International Normalised Ratio (INR) have been reported during concomitant treatment in the post-marketing period.
Slovenian: Kumarinski antikoagulanti (fenprokumon ali varfarin) Čeprav v kliničnih farmakokinetičnih študijah niso opazili nobenega medsebojnega delovanja pri sočasni uporabi fenprokumona ali varfarina, so v post-marketinškem obdobju zabeležili nekaj posameznih primerov spremenjenih vrednosti INR (International Normalised Ratio) ob sočasnem zdravljenju.
English: - If you suffer from severe liver problems, you should not take more than one tablet 20 mg pantoprazole a day (for this purpose tablets containing 20 mg pantoprazole are available).
Slovenian: - Če imate hude težave z jetri, ne smete vzeti več kot 1 tableto 20 mg pantoprazola (za ta namen se dobijo tablete, ki vsebujejo 20 mg pantoprazola).
English: Since pantoprazole binds to the enzyme distal to the cell receptor level, it can inhibit hydrochloric acid secretion independently of stimulation by other substances (acetylcholine, histamine, gastrin).
Slovenian: Ker se pantoprazol veže na encim distalno od celičnega receptorja, lahko zavira izločanje klorovodikove kisline neodvisno od stimulacije z drugimi snovmi (acetilholin, histamin, gastrin).
English: These findings have no implications for the posology of pantoprazole.
Slovenian: Te ugotovitve ne vplivajo na način odmerjanja pantoprazola.
English: After healing of the relapse the dose can be reduced again to 20 mg pantoprazole.
Slovenian: Po ozdravitvi lahko zmanjšamo odmerek spet na 20 mg pantoprazola.
English: In the two-year rodent studies an increased number of liver tumors was observed in rats and in female mice and was interpreted as being due to pantoprazole's high metabolic rate in the liver.
Slovenian: V dvoletnih raziskavah na glodalcih so pri podganah in pri mišjih samicah opazili povečano število jetrnih tumorjev, ki naj bi nastali zaradi močno povečanega presnavljanja pantoprazola v jetrih.
English: Renal elimination represents the major route of excretion (about 80 %) for the metabolites of pantoprazole, the rest is excreted with the faeces.
Slovenian: Glavna pot izločanja njegovih presnovkov je preko ledvic (približno 80%), preostanek se izloča z blatom.
English: Any increased risk will be assessed according to your own personal risk factors such as your age (65 years old or more), a history of stomach or duodenal ulcers or of stomach or intestinal bleeding.
Slovenian: Kakršnokoli tveganje je treba oceniti glede na vaše osebne dejavnike tveganja kot so vaša starost (65 let ali več), če ste že imeli razjedo želodca ali dvanajstnika ali krvavitve iz želodca ali črevesja.
English: In the dose range of 10 to 80 mg, the plasma kinetics of pantoprazole are linear after both oral and intravenous administration.
Slovenian: V razponu odmerkov od 10 do 80 mg je plazemska kinetika pantoprazola linearna, tako za peroralni kot tudi za intravenski vnos.
English: Adverse drug reactions such as dizziness and visual disturbances may occur (see section 4.8).
Slovenian: Pojavijo se lahko neželeni učinki kot so vrtoglavica in motnje vida (glejte poglavje 4.8).
English: Do not use Protium if you notice that the visual appearance has changed (e.g. if cloudiness or precipitation is observed).
Slovenian: Ne uporabite zdravila Protium, če opazite, da se je izgled raztopine spremenil (npr. zapazite motnost ali usedlino).
English: After preparation the solution must be used within 12 hours.
Slovenian: Po pripravi moramo raztopino uporabiti v 12 urah.
English: Because of the specific binding of pantoprazole to the proton pumps of the parietal cell the elimination half-life does not correlate with the much longer duration of action (inhibition of acid secretion).
Slovenian: Zaradi specifične vezave pantoprazola na protonsko črpalko parietalnih celic, razpolovni čas izločanja ni v korelaciji z njegovim veliko daljšim delovanjem (zaviranje izločanja kisline).
English: After this any recurring symptoms can be controlled by taking one tablet daily, when required.
Slovenian: Po tem lahko ponovno pojavljanje simptomov zdravite z jemanjem 1 tablete na dan, po potrebi.
English: PHARMACEUTICAL FORM AND CONTENTS Pack with 5 gastro-resistant tablets.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Pakiranje s 5 gastrorezistentnimi tabletami.
English: After a single-dose administration of 40 mg pantoprazole, the mean area under the plasma concentration-time curve was approximately 6 times higher in poor metabolisers than in subjects having a functional CYP2C19 enzyme (extensive metabolisers).
Slovenian: Po vnosu enkratnega odmerka 40 mg pantoprazola je bila pri šibkih presnavljalcih povprečna površina pod krivuljo plazemske koncentracije v odvisnosti od časa približno 6-krat večja kot pri osebah z delujočim encimom CYP2C19 (močni presnavljalci).
English: As pantoprazole is extensively protein bound, it is not readily dialysable.
Slovenian: Pantoprazol je pretežno vezan na proteine, zato ga je težko dializirati.
English: Hungary Ireland
Slovenian: Madžarska Irska
English: Hospital pack with 1 vial.
Slovenian: Bolnišnično pakiranje z 1 vialo.
English: Driving and using machines If you experience side effects like dizziness or disturbed vision, you should not drive or operate machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Če se pojavita neželena učinka kot sta vrtoglavica ali motnje vida, ne smete voziti ali upravljati s stroji.
English: Interaction studies with drugs also metabolized with these pathways, like carbamazepine, diazepam, glibenclamide, nifedipine, and an oral contraceptive containing levonorgestrel and ethinyl oestradiol did not reveal clinically significant interactions.
Slovenian: Študije medsebojnega delovanja z zdravili, ki se tudi presnavljajo po teh poteh kot karbamazepin, diazepam, glibenklamid, nifedipin in peroralni kontraceptivi, ki vsebujejo levonorgestrel in etinilestradiol, niso pokazale klinično pomembnih interakcij.
English: For instructions for preparation see section 6.6.
Slovenian: Za navodila o ravnanju z zdravilom glejte poglavje 6.6.
English: If this is not sufficient, healing will usually be achieved within a further 4 weeks.
Slovenian: Če to ne zadošča, običajno dosežemo ozdravitev v naslednjih 4 tednih.
English: No dose reduction is recommended when pantoprazole is administered to patients with impaired renal function (including dialysis patients).
Slovenian: Odmerka pantoprazola ni potrebno zmanjšati pri bolnikih z okvarjeno ledvično funkcijo (vključno z dializnimi bolniki).
English: Co-administration of atazanavir and other HIV medications whose absorption is pH-dependent with proton-pump inhibitors might result in a substantial reduction in the bioavailability of these HIV medications and might impact the efficacy of these medicines.
Slovenian: Sočasno jemanje zdravila atazanavir in drugih zdravil proti HIV, katerih absorpcija je odvisna od pH, bi lahko skupaj z zaviralci protonske črpalke povzročilo pomembno zmanjšanje biološke razpoložljivosti teh zdravil proti HIV in bi lahko vplivalo na učinkovitost teh zdravil.
English: - Medicines such as ketoconazole, itraconazole and posaconazole (used to treat fungal infections) or erlotinib (used for certain types of cancer) because Protium may stop these and other medicines from working properly.
Slovenian: - zdravila kot npr. ketokonazol, itrakonazol in posakonazol (ki se uporablja za zdravljenje glivičnih okužb) ali erlotinib (ki se uporablja za zdravljenje nekaterih vrst raka), ker lahko zdravilo Protium prepreči pravilno delovanje tem in drugim zdravilom.
English: After healing, you can reduce the dose back again to one tablet 20 mg a day.
Slovenian: Po ozdravitvi lahko odmerek zmanjšate nazaj na 1 tableto 20 mg na dan.
English: Other side effects are: - Common (affects 1 to 10 users in 100) inflammation of the wall of the vein and blood clotting (thrombophlebitis) where the medicine is injected.
Slovenian: Ostali neželeni učinki so: - Pogosti (pojavijo se pri 1 do 10 od 100 bolnikov) vnetje stene vene in strjevanje krvi (tromboflebitis) na mestu injiciranja zdravila.
English: Therefore, in patients treated with coumarin anticoagulants (e.g. phenprocoumon or warfarin), monitoring of prothrombin time / INR is recommended after initiation, termination or during irregular use of pantoprazole.
Slovenian: Pri bolnikih, ki se zdravijo s kumarinskimi antikoagulanti (npr. fenprokumon ali varfarin), je zato priporočljivo spremljati vrednosti protrombinskega časa/INR ob začetku, zaključku zdravljenja s pantoprazolom ali v primeru neredne uporabe pantoprazola.
English: Pharmacotherapeutic group: Proton pump inhibitors, ATC code: A02BC02
Slovenian: Farmakoterapevtska skupina: zaviralci protonske črpalke, oznaka ATC: A02BC02
English: If you get any of the following side effects, stop taking these tablets and tell your doctor immediately, or contact the casualty department at your nearest hospital:
Slovenian: Če se pojavi katerikoli od naslednjih neželenih učinkov, prenehajte jemati te tablete in takoj obvestite svojega zdravnika ali se posvetujte z nezgodnim oddelkom v najbližji bolnišnici:
English: He will check your liver enzymes more frequently, especially when you are taking Protium as a long-term treatment.
Slovenian: Pogosteje vam bo kontroliral jetrne encime, predvsem pri dolgotrajnem zdravljenju z zdravilom Protium.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION {DD/MM/YYYY} [To be completed nationally]
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET {DD/MM/LLLL} [Izpolni država članica]
English: This medicinal product contains soya oil.
Slovenian: To zdravilo vsebuje sojino olje.
English: What Protium looks like and contents of the pack
Slovenian: Izgled zdravila Protium in vsebina pakiranja
English: - Children below 12 years.
Slovenian: - Otroci mlajši od 12 let.
English: Special patient groups:
Slovenian: Posebne skupine bolnikov
English: If you need to take medicines called NSAIDs continuously and receive Protium because you have an increased risk of developing stomach and intestinal complications.
Slovenian: - če potrebujete neprekinjeno zdravljenje z nesteroidnimi protivnetnimi zdravili in prejemate zdravilo Protium, ker imate visoko tveganje za pojav želodčnih in črevesnih zapletov.
English: Although for patients with liver cirrhosis (classes A and B according to Child) the half-life values increased to between 7 and 9 h and the AUC values increased by a factor of 5 - 7, the maximum serum concentration only increased slightly by a factor of 1.5 compared with healthy subjects.
Slovenian: Čeprav se pri bolnikih z jetrno cirozo (razred A in B po Childu) razpolovni čas podaljša na 7-9 ur in AUC vrednosti narastejo s faktorjem 5-7, poraste maksimalna plazemska koncentracija komaj opazno, s faktorjem 1,5 v primerjavi z zdravimi osebami.
English: Pantoprazole is extensively metabolized in the liver via the cytochrome P450 enzyme system.
Slovenian: Druge študije medsebojnega delovanja Pantoprazol se obširno presnavlja v jetrih preko encimskega sistema citokrom P450.