FrancophonIA/ELRC3.0 huggingface dataset:
English: The concurrent use of immediate-release exenatide with D-phenylalanine derivatives (meglitinides), alpha-glucosidase inhibitors, dipeptidyl peptidase-4 inhibitors or other GLP-1 receptor agonists has not been studied and cannot be recommended.
Croatian: Istodobna primjena eksenatida s trenutnim oslobađanjem s derivatima D-fenilalanina (meglitinidima), inhibitorima alfa-glukozidaze, inhibitorima dipeptidil peptidaze- 4 ili drugim agonistima GLP-1 receptora nije ispitivana te se ne može preporučiti.
English: In the 30-week placebo-controlled clinical trials, concomitant use of immediate-release exenatide and HMG CoA reductase inhibitors was not associated with consistent changes in lipid profiles (see section 5.1).
Croatian: U 30-tjednim placebom kontroliranim kliničkim ispitivanjima, istodobna primjena eksenatida s trenutnim oslobađanjemi inhibitora HMG KoA reduktaze nije bila povezana s konzistentnim promjenama lipidnog statusa (vidjeti dio 5.1).
English: Your doctor may tell you to use Byetta 5 micrograms twice a day to start with.
Croatian: Liječnik će Vam možda reći da za početak koristite lijek Byetta 5 mikrograma dvaput na dan.
English: Immediate-release exenatide (Byetta) therapy should be initiated at 5 mcg exenatide per dose administered twice daily (BID) for at least one month in order to improve tolerability.
Croatian: Terapija eksenatidom s trenutnim oslobađanjem (Byetta) mora započeti dozom od 5 µg eksenatida koja se primjenjuje dvaput na dan tijekom najmanje mjesec dana kako bi se poboljšala podnošljivost.
English: Immediate-release exenatide can be administered at any time within the 60-minute period before the morning and evening meal (or two main meals of the day, approximately 6 hours or more apart).
Croatian: Eksenatid s trenutnim oslobađanjem se može primijeniti bilo kada unutar 60 minuta prije jutarnjeg i večernjeg obroka (odnosno prije dvaju glavnih dnevnih obroka između kojih je vremenski razmak najmanje 6 sati).
English: The patient should be instructed to discard the needle after each injection.
Croatian: Bolesnika treba uputiti da nakon svake injekcije zbrine iglu.
English: • The liquid should be clear, colourless, and free of particles.
Croatian: • Tekućina mora biti bistra, bezbojna i bez čestica.
English: Hence, no restriction in timing of intake of these medicinal products in relation to immediate-release exenatide injection are needed.
Croatian: Stoga nisu potrebna nikakva ograničenja vezana uz vrijeme uzimanja ovih lijekova u odnosu na injekciju eksenatida s trenutnim oslobađanjem
English: Therefore, the use of exenatide is not recommended in patients with severe gastrointestinal disease.
Croatian: Stoga se ne preporučuje primjena eksenatida u bolesnika s teškom gastrointestinalnom bolešću.
English: The reduction in HbA1c was sustained and the weight loss continued for at least 82 weeks in the subset of 10 mcg BID patients completing both the placebo-controlled studies and the uncontrolled study extensions (n=137).
Croatian: Vidjeti Tablicu 2. Sniženje HbA1c se održalo, a gubitak težine nastavio tijekom najmanje 82 tjedna u podskupini bolesnika liječenih dozom od 10 µg dvaput na dan koji su dovršili i placebom kontrolirana ispitivanja i nekontrolirane produžetke ispitivanja (n=137).
English: Signs and symptoms of overdose may include severe nausea, severe vomiting and rapidly declining blood glucose concentrations.
Croatian: Znakovi i simptomi predoziranja mogu uključivati tešku mučninu, jako povraćanje te brz pad koncentracije glukoze u krvi.
English: For additional information, contact your healthcare professional.
Croatian: Za dodatne informacije obratite se svom zdravstvenom radniku.
English: • DO NOT TRANSFER THE MEDICINE IN THE BYETTA PEN TO A SYRINGE.
Croatian: • NEMOJTE PRENOSITI LIJEK IZ BYETTA BRIZGALICE U ŠTRCALJKU.
English: When 1000 mg paracetamol was given with 10 mcg immediate-release exenatide (0 h) and 1 h, 2 h and 4 h after immediate-release exenatide injection, paracetamol AUCs were decreased by 21%, 23%, 24% and 14% respectively; Cmax was decreased by 37%, 56%, 54% and 41%, respectively; tmax was increased from 0.6 h in the control period to 0.9 h, 4.2 h, 3.3 h, and 1.6 h, respectively.
Croatian: Kada je doza od 1000 mg paracetamola primijenjena istodobno s dozom od 10 µg eksenatida s trenutnim oslobađanjem (0 sati) te 1 sat, 2 sata odnosno 4 sata nakon injekcije eksenatida s trenutnim oslobađanjem , AUC paracetamola smanjio se za 21%, 23%, 24% odnosno 14%; Cmax se smanjio za 37%, 56%, 54%, odnosno 41%; tmax se povećao s 0,6 sati u kontrolnom razdoblju na 0,9 sati, 4,2 sata, 3,3 sata, odnosno 1,6 sati.
English: However, since market introduction, increased INR (International Normalized Ratio) has been reported spontaneously during concomitant use of warfarin and exenatide.
Croatian: Međutim, nakon stavljanja lijeka u promet spontano je prijavljen je povećan INR (međunarodni normalizirani omjer) tijekom istodobne primjene varfarina i eksenatida.
English: • injection site reactions (redness)
Croatian: • reakcije na mjestu injekcije (crvenilo)
English: B.CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Croatian: UVJETI ILI OGRANIČENJA VEZANI UZ OPSKRBU I PRIMJENU
English: When immediate-release exenatide is added to existing metformin and/or pioglitazone therapy, the current dose of metformin and/or pioglitazone can be continued as no increased risk of hypoglycaemia is anticipated, compared to metformin or pioglitazone alone.
Croatian: Kada se eksenatid s trenutnim oslobađanjem dodaje postojećoj terapiji metforminom i/ili pioglitazonom, može se nastaviti s dotadašnjom dozom meformina i/ili pioglitazona, s obzirom da se ne očekuje povećan rizik od hipoglikemije u usporedbi s primjenom samog meformina ili pioglitazona.
English: At the end of the study, immediate-release exenatide (n=137) demonstrated a statistically significant reduction in the HbA1c and weight compared to placebo (n=122).
Croatian: Na kraju ispitivanja eksenatida s trenutnim oslobađanjem je (n=137) postignuto statistički značajno sniženje vrijednosti HbA1c i tjelesne težine u usporedbi s placebom (n=122).
English: These medicinal products should be taken in a standardised way in relation to immediate-release exenatide injection.
Croatian: Ti se lijekovi trebaju uzimati na standardiziran način u odnosu na injekciju eksenatida s trenutnim oslobađanjem
English: Administration of the oral contraceptive 30 minutes after immediate-release exenatide did not affect AUC but resulted in a reduction of the Cmax of ethinyl estradiol by 45%, and Cmax of levonorgestrel by 27-41%, and a delay in tmax by 2-4 h due to delayed gastric emptying.
Croatian: Primjena oralnog kontraceptiva 30 minuta nakon injekcije eksenatida s trenutnim oslobađanjem nije utjecala na AUC, ali je uzrokovala smanjenje Cmax etinilestradiola za 45%, smanjenje Cmax levonorgestrela za 27-41% te odgodu tmax za 2-4 sata zbog produljenog pražnjenja želuca.
English: The dose of exenatide can then be increased to 10 mcg BID to further improve glycaemic control.
Croatian: Doza eksenatida se tada može povećati na 10 µg dvaput na dan kako bi se dodatno poboljšala kontrola glikemije.
English: If you stop using Byetta
Croatian: Ako prestanete uzimati lijek Byetta
English: 6.1 List of excipients metacresol mannitol glacial acetic acid sodium acetate trihydrate water for injections
Croatian: 6.1 Popis pomoćnih tvari metakrezol manitol acetatna kiselina, ledena natrijev acetat trihidrat voda za injekcije
English: Both treatment arms were titrated to achieve target fasting plasma glucose levels (see section 5.1).
Croatian: U obje su terapijske skupine doze titrirane kako bi se postigla ciljna razina glukoze u plazmi natašte (vidjeti dio 5.1).
English: The liquid should be clear, colourless, and free of particles.
Croatian: Tekućina mora biti bistra, bezbojna i bez čestica.
English: • Check pen label to make sure it is your 5 microgram pen.
Croatian: • Provjerite naljepnicu brizgalice kako biste bili sigurni da je to Vaša brizgalica od 5 mikrograma.
English: It is not known if exenatide passes into your milk.
Croatian: Nije poznato izlučuje li se eksenatid u majčino mlijeko.
English: (See Storing Your ByettaPenin Section 1 of this user manual for more information.)
Croatian: (Za više informacija pogledajte Čuvanje Byetta brizgalice u Dijelu 1. ovih Uputa za uporabu).
English: There were no clinically relevant differences in incidence or severity of hypoglycaemia with exenatide compared to placebo, in combination with a thiazolidinedione, with or without metformin.
Croatian: Nije bilo klinički značajne razlike u incidenciji i težini hipoglikemije pri primjeni eksenatida u odnosu na placebo u kombinaciji s tiazolidindionom, s metforminom ili bez njega.
English: During the study both treatment arms titrated insulin glargine using an algorithm reflecting current clinical practice to a target fasting plasma glucose of approximately 5.6 mmol/l.
Croatian: Tijekom ovog ispitivanja se u obje terapijske skupine inzulin glargin titrirao pomoću algoritma koji odražava trenutnu kliničku praksu do postizanja ciljne razine glukoze u plazmi natašte od približno 5,6 mmol/l.
English: Immediate-release exenatide-treated patients in the open-label extension studies at 82 weeks experienced similar types of adverse events observed in the controlled trials.
Croatian: Bolesnici liječeni eksenatidom s trenutnim oslobađanjem su u otvorenim produžecima ispitivanjima nakon 82 tjedna doživjeli slične vrste nuspojava kao i u kontroliranim ispitivanjima.
English: Byetta should be injected into your abdomen, thigh, or upper arm using the injection technique recommended by your healthcare professional.
Croatian: Byetta se mora injicirati u područje trbuha, bedra ili nadlaktice, koristeći tehniku injiciranja koju Vam je preporučio zdravstveni radnik.
English: Clearance was significantly reduced by 84% in patients with end-stage renal disease receiving dialysis (see section 4.2).
Croatian: Klirens je bio značajno smanjen, za 84%, u bolesnika u terminalnoj fazi bubrežne bolesti liječenih dijalizom (vidjeti dio 4.2).
English: C.OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION
Croatian: OSTALI UVJETI I ZAHTJEVI ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET
English: System organ class /adverse reaction terms
Croatian: Klasifikacija organskih sustava / pojmovi nuspojava
English: STEP 7 Store Pen for Next Dose
Croatian: KORAK 7. Spremite brizgalicu za sljedeću dozu
English: Your doctor or nurse must teach you how to inject Byetta before you use it for the first time.
Croatian: Prije prve uporabe Vaš liječnik ili medicinska sestra Vas moraju naučiti kako ćete primijeniti lijek Byetta.
English: International normalised ratio increased with concomitant warfarin, some reports associated with bleeding
Croatian: Pretrage smanjenje tjelesene težine povišenje međunarodnog normaliziranog omjera kod istodobne primjene varfarina; neke prijave bile su povezane s krvarenjem
English: The clinical experience in patients with moderate renal impairment is very limited (see section 4.2).
Croatian: Kliničko iskustvo s bolesnicima s umjerenim oštećenjem bubrega vrlo je oskudno (vidjeti dio 4.2).
English: Exenatide exposure increased proportionally over the therapeutic dose range of 5 mcg to 10 mcg.
Croatian: Izloženost eksenatidu proporcionalno se povećavala u terapijskom rasponu doza između 5 μg i 10 μg.
English: STEP 5 Reset the Pen
Croatian: KORAK 5. Ponovno namjestite brizgalicu
English: Administration of exenatide has been shown to reduce food intake, due to decreased appetite and increased satiety.
Croatian: Zabilježeno je da primjena eksenatida smanjuje unos hrane, zbog smanjena teka i povećane sitosti.
English: If you forget to use Byetta
Croatian: Ako ste zaboravili primijeniti lijek Byetta
English: Following a basal insulin optimization (BIO) phase, patients with HbA1c7.0% were randomized to add either immediate-release exenatide or insulin lispro to their existing regimen of insulin glargine and metformin.
Croatian: Nakon faze optimizacije bazalnog inzulina (OBI), bolesnici sa HbA1c 7,0% bili su randomizirani da dodaju bilo eksenatid s trenutnim oslobađanjem bilo inzulin lispro na već postojeći režim uzimanja inzulin glargina i metformina.
English: Treatment differences (immediate-release exenatide minus comparator) were -4.1 kg in the 26-week study and -5.4 kg in the 52-week study.
Croatian: Razlike između terapija (eksenatid s trenutnim oslobađanjem minus usporedni lijek) iznosile su -4,1 kg u 26-tjednom ispitivanju te -5,4 kg u 52-tjednom ispitivanju.
English: STEP D Prepare the Pen
Croatian: KORAK D. Pripremite brizgalicu
English: Each pen has 60 doses to provide 30 days of twice-aday injections.
Croatian: U svakoj brizgalici nalazi se 60 doza lijeka, što omogućuje primjenu dvije injekcije na dan tijekom 30 dana.
English: • Check pen label to make sure it is your 10 microgram pen.
Croatian: • Provjerite naljepnicu brizgalice kako biste bili sigurni da je to Vaša brizgalica od 10 mikrograma.
English: Table 1 lists adverse reactions reported of immediate-release exenatide from clinical trials and spontaneous reports (not observed in clinical trials, frequency not known).
Croatian: Tablici 1 popisane su nuspojave na eksenatida s trenutnim oslobađanjem prijavljene tijekom kliničkih ispitivanja i spontane prijave (nisu zamijećene u kliničkim ispitivanjima, učestalost je nepoznata).
English: There were no clinically significant differences in the incidence of hypoglycaemic episodes in the immediate-release exenatide compared to the placebo group (25% and 29% respectively).
Croatian: Nije bilo klinički značajnih razlika u incidenciji epizoda hipoglikemije između skupine koja je primala eksenatid s trenutnim oslobađanjem i skupine koja je primala placebo (25% odnosno 29%).
English: Immediate-release exenatide should be used with caution in patients receiving oral medicinal products that require rapid gastrointestinal absorption and medicinal products with a narrow therapeutic ratio.
Croatian: Eksenatid s trenutnim oslobađanjem se treba primjenjivati uz oprez u bolesnika koji peroralno primaju lijekove koji zahtijevaju brzu gastrointestinalnu apsorpciju i lijekove uskog terapijskog indeksa.
English: High doses of exenatide during mid-gestation caused skeletal effects and reduced foetal growth in mice and reduced foetal growth in rabbits.
Croatian: Visoke doze eksenatida tijekom srednje faze gestacije izazvale su učinke na kosturu te usporile fetalni rast u miševa i kunića.
English: Type I glass cartridge with a (bromobutyl) rubber plunger, rubber disc, and aluminium seal.
Croatian: Stakleni uložak (staklo tipa I), s gumenim (bromobutil) klipom, gumenim diskom i aluminijskim prstenom.
English: Patients in the immediate-release exenatide-treated group with anHbA1c 8.0% at the end of the BIO phase decreased their insulin glargine dose by at least 10%.
Croatian: Bolesnici u skupini liječeni eksenatidom s trenutnim oslobađanjem sa HbA1c 8,0% na kraju faze OBI smanjili su svoju dozu inzulin glargina za najmanje 10%.
English: All patients assigned to immediate-release exenatide initially received 5 mcg BID for four weeks.
Croatian: Svi bolesnici kojima je propisan eksenatid s trenutnim oslobađanjem na početku su dobivali 5 μg dvaput dnevno tijekom četiri tjedna.
English: A small amount of Byetta will always remain in the cartridge.
Croatian: U ulošku će uvijek ostati mala količina lijeka Byetta.
English: • Keep the pressure on the injection button as you remove the needle from your skin, this keeps the medication in the cartridge clear.
Croatian: • Držite pritisnutim gumb za injiciranje dok vadite iglu iz kože, to će osigurati da lijek u ulošku ostane bistar.
English: Immediate-release exenatide is recommended for use in patients with type 2 diabetes mellitus who are already receiving metformin, a sulphonylurea, pioglitazone and/or a basal insulin.
Croatian: Primjena eksenatida s trenutnim oslobađanjem preporučuje se u bolesnika koji boluju od šećerne bolesti tipa 2 i koji već primaju metformin, sulfonilureju, pioglitazon i/ili bazalni inzulin.
English: Immediate-release exenatide improves glycaemic control through the immediate and sustained effects of lowering both postprandial and fasting glucose concentrations in patients with type 2 diabetes.
Croatian: Eksenatid s trenutnim oslobađanjem poboljšava kontrolu glikemije u bolesnika sa šećernom bolešću tipa 2 putem neposrednih i kontinuiranih učinaka sniženja koncentracije glukoze, kako postprandijalno tako i natašte.
English: In a pharmacokinetic study in patients with type 2 diabetes, administration of exenatide (10 mcg) resulted in a mean increase of exenatide AUC by 36% in 15 elderly subjects aged 75 to 85 years compared to 15 subjects aged 45 to 65 years likely related to reduced renal function in the older age group (see section 4.2).
Croatian: U farmakokinetičkom ispitivanju u bolesnika sa šećernom bolešću tipa 2, primjena eksenatida (10 µg) rezultirala je prosječnim povećanjem AUC-a eksenatida za 36% u 15 starijih ispitanika u dobi od 75 do 85 godina u usporedbi s 15 ispitanika u dobi od 45 do 65 godina, što je najvjerojatnije povezano sa smanjenom bubrežnom funkcijom u starijoj dobnoj skupini (vidjeti dio 4.2).
English: Byetta is indicated for treatment of type 2 diabetes mellitus in combination with: - metformin - sulphonylureas - thiazolidinediones - metformin and a sulphonylurea - metformin and a thiazolidinedione in adults who have not achieved adequate glycaemic control on maximally tolerated doses of these oral therapies.
Croatian: Byetta je indicirana za liječenje šećerne bolesti tipa 2 u kombinaciji s: - metforminom - sulfonilurejom - tiazolidindionom - metforminom i sulfonilurejom - metforminom i tiazolidindionom u odraslih bolesnika u kojih glikemija nije dovoljno dobro regulirana najvišim podnošljivim dozama ovih peroralnih lijekova.
English: Exenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that exhibits several antihyperglycaemic actions of glucagon-like peptide-1 (GLP-1).
Croatian: Eksenatid je agonist receptora peptida-1 nalik glukagonu (engl. glucagon-like peptide-1, GLP-1) koji iskazuje nekoliko antihiperglikemijskih aktivnosti peptida-1 nalik glukagonu (GLP-1).
English: In patients with mild (creatinine clearance 50 to 80 ml/min) or moderate renal impairment (creatinine clearance 30 to 50 ml/min), exenatide clearance was mildly reduced compared to clearance in individuals with normal renal function (13% reduction in mild and 36% reduction in moderate renal impairment).
Croatian: U bolesnika s blagim (klirens kreatinina 50 do 80 ml/min) ili umjerenim oštećenjem bubrega (klirens kreatinina 30 do 50 ml/min), klirens eksenatida bio je malo umanjen u usporedbi s osobama s normalnom bubrežnom funkcijom (13% manji kod blagog, a 36% manji kod umjerenog oštećenja bubrega).
English: Do not use this medicine after the expiry date, which is stated on the label and the carton after ‘EXP'.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na naljepnici i kutiji iza oznake „EXP“.
English: keep out air bubbles, reduce needle clogs, and decrease the risk of infection.
Croatian: Tako ćete spriječiti istjecanje lijeka Byetta i stvaranje mjehurića zraka, smanjiti mogućnost začepljenja igle i umanjiti rizik od infekcije.
English: The most frequent adverse reactions were mainly gastrointestinal related (nausea, vomiting and diarrhoea).
Croatian: Najčešće nuspojave uglavnom su bile vezane uz probavni sustav (mučnina, povraćanje i proljev).
English: There have been uncommon, spontaneously reported events of altered renal function, including increased serum creatinine, renal impairment, worsened chronic renal failure and acute renal failure, sometimes requiring hemodialysis.
Croatian: Zabilježeni su manje česte spontane prijave o slučajevima promjene bubrežne funkcije, uključujući povišene vrijednosti serumskog kreatinina, oštećenje bubrežne funkcije, pogoršanje kroničkog zatajivanja bubrega i akutno zatajenje bubrega, zbog kojeg je ponekad bila potrebna hemodijaliza.
English: The 26-week study showed similar results with statistically significant reductions from baseline HbA1c compared to placebo (-0.8% versus -0.1%).
Croatian: Rezultati 26-tjednog ispitivanja bili su slični te su pokazali statistički značajno sniženje od početne vrijednosti HbA1c u odnosu na placebo (-0,8% naspram0,1%).
English: Two placebo-controlled studies were conducted: one of 16 and one of 26 weeks duration, with 121 and 111 immediate-release exenatide and 112 and 54 placebo treated patients respectively, added to existing thiazolidinedione treatment, with or without metformin.
Croatian: Provedena su dva placebom kontrolirana ispitivanja: jedno u trajanju od 16 tjedana, s 121 bolesnikom koji je primao eksenatid s trenutnim oslobađanjem i 112 bolesnika koji su primali placebo, a drugo u trajanju od 26 tjedana, sa 111 bolesnika liječenih eksenatidom s trenutnim oslobađanjem i 54 bolesnika koji su primali placebo.
English: Most episodes of hypoglycaemia were mild to moderate in intensity, and resolved with oral administration of carbohydrate.
Croatian: Većina epizoda hipoglikemije bila je blagog do umjerenog intenziteta te je regulirana peroralnim uzimanjem ugljikohidrata.
English: Make sure needle is on straight and screwed on all the way.
Croatian: Provjerite da je igla pričvršćena ravno i navijena do kraja.
English: Store in a refrigerator (2 ºC - 8 ºC).
Croatian: Čuvati u hladnjaku (2 °C - 8 °C).
English: • Remove the needle after each injection.
Croatian: • Skinite iglu nakon svake injekcije.
English: The New Pen Setup is done only once, just before each new pen is used for the first time.
Croatian: Podešavanje nove doze vrši se samo jedanput, neposredno prije prve uporabe svake nove brizgalice.
English: Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, particularly: - medicines that are used to treat type 2 diabetes that work like Byetta (e.g. liraglutide and prolonged-release exenatide), as taking these medicines with Byetta is not recommended.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzimali ili bi mogli uzeti bilo koje druge lijekove, pogotovo: - lijekove koji se koriste za liječenje šećerne bolesti tipa 2 koji djeluju na isti način kao Byetta (npr. liraglutid i eksenatid sa produljenim oslobađanjem), jer se uzimanje tih lijekova sa Byettom ne preporučuje - lijekove koji se koriste za razrjeđivanje krvi (antikoagulanse), npr. varfarin, jer će Vam trebati dodatno praćenje promjena u INR-u (mjera razrjeđenja krvi) tijekom početka terapije ovim lijekom.
English: For additional information contact your healthcare professional.
Croatian: Za dodatne informacije obratite se zdravstvenom radniku.
English: In a 30-week, open-label, active comparator-controlled, noninferiority study, the safety and efficacy of immediate-release exenatide (n=315) versus titrated insulin lispro three times daily (n=312) on a background of optimized basal insulin glargine and metformin in patients with type 2 diabetes was evaluated.
Croatian: U 30-tjednom, otvorenom ispitivanju neinferiornosti kontroliranom aktivnim komparatorom, ocijenjena je sigurnost i djelotvornost eksenatida s trenutnim oslobađanjem (n=315) naspram titriranog inzulina lispro triput dnevno (n=312) uz osnovnu optimiziranu terapiju bazalnog inzulina glargina i metformina kod bolesnika s dijabetesom tipa 2.
English: • Point the needle of the pen up and away from you.
Croatian: • Usmjerite iglu brizgalice prema gore i od sebe.
English: Seven-point self-monitored blood glucose profiles (before and after meals and at 3 am) demonstrated significantly reduced glucose values compared to insulin in the postprandial periods after immediate-release exenatide injection.
Croatian: Profili glukoze u krvi dobiveni samokontrolom u sedam vremenskih točaka (prije i nakon obroka te u 3 sata ujutro) pokazali su značajno niže vrijednosti glukoze u postprandijalnim razdobljima nakon injekcije eksenatida s trenutnim oslobađanjem u odnosu na inzulin.
English: Insert needle into skin using hygienic injection technique recommended by your healthcare professional.
Croatian: Ubodite iglu u kožu primjenjujući higijensku tehniku injiciranja koju Vam je preporučio zdravstveni radnik.