FrancophonIA/ELRC3.0 huggingface dataset:
English: DO NOT turn the cartridge to [3] (Step 6b) before attaching the needle (Step 5).
Danish: DU MÅ IKKE dreje cylinderampullen til [3] (trin 6b), før du sætter nålen på (trin 5).
English: Thyroid C-cell tumours were observed in 2 year rodent carcinogenicity studies with other GLP-1 receptor agonists.
Danish: Der blev observeret thyreoidea-C-celle-tumorer i karcinogenicitetsstudier af 2 års varighed hos gnavere, som fik andre GLP-1-receptoragonister.
English: Background therapies in these studies included diet and exercise, metformin, sulphonylurea, thiazolidinedione, insulin glargine, or a combination of antidiabetic medicinal products.
Danish: Baggrundsbehandlingerne i disse studier omfattede kost og motion, metformin, sulfonylurinstof, thiazolidindion, insulin glargin eller en kombination af antidiabetika.
English: Albiglutide is a protein for which the expected metabolic pathway is degradation to small peptides and individual amino acids by ubiquitous proteolytic enzymes.
Danish: Albiglutid er et protein, som forventes at blive metaboliseret ved nedbrydning til små peptider og de enkelte aminosyrer via ubikvitære proteolytiske enzymer.
English: Other side effects reported with Eperzan
Danish: Andre bivirkninger rapporteret for Eperzan
English: In a population pharmacokinetic analysis including a phase III trial in patients with mild, moderate and severe renal impairment, exposures were increased by approximately 30 to 40% in severe renal impairment compared to those observed in type 2 diabetic patients with normal renal function.
Danish: I en farmakokinetisk populationsanalyse, der omfattede et fase III-studie hos patienter med let, moderat og svært nedsat nyrefunktion, blev eksponeringerne øget med ca. 30-40 % ved svært nedsat nyrefunktion sammenlignet med de eksponeringer, der blev observeret hos patienter med type 2-diabetes med normal nyrefunktion.
English: Throw out the pen in a container for pen disposal right away after injecting, as shown in Step 9.
Danish: Kasser pennen i en beholder til den brugte pen lige efter, at du har injiceret som anført i trin 9.
English: The pain may happen with or without you being sick (vomiting).
Danish: Smerterne kan optræde med eller uden opkastning.
English: Anticipated symptoms of an overdose may be severe nausea, vomiting or headache.
Danish: Symptomer på overdosering kan forventes at være svær kvalme, opkastning eller hovedpine.
English: Instruct the patient to read the full Instructions for Use (IFU) including the Questions and Answers before starting the therapy and refer back to the IFU each time before injecting the dose.
Danish: Patienten skal instrueres i at læse hele vejledningen i indlægssedlen, herunder de ofte stillede spørgsmål før behandlingen startes samt at referere tilbage til vejledningen før hver dosis injiceres.
English: Insulin glargine  Metformin (with or without sulphonylurea)
Danish: Insulin glargin  metformin (med eller uden sulfonylurinstof)
English: Tell your doctor, nurse or pharmacist immediately if you become pregnant during treatment with Eperzan.
Danish: Fortæl det omgående til lægen, sundhedspersonalet eller apotekspersonalet, hvis du bliver gravid under behandlingen med Eperzan.
English: The mean daily dose of insulin lispro at Week 26 was 31 IU, and at Week 52, 69% of patients treated with Eperzan were on 50 mg weekly.
Danish: Den gennemsnitlige daglige dosis af insulin lispro ved uge 26 var 31 IE, og ved uge 52 var 69 % af patienterne i Eperzan-armen på 50 mg ugentligt.
English: After mixing, wait 15 minutes before injection
Danish: Efter sammenblanding, vent 15 minutter før injektion.
English: Studies in mice showed reduced oestrous cycling at maternally toxic doses, but did not indicate harmful effects with respect to fertility (see section 5.3).
Danish: Studier hos mus viste kortere brunstcyklusser ved maternelt toksiske doser, men indikerede ikke skadelige virkninger, hvad angik fertilitet (se pkt.
English: In clinical trials of at least 2 years duration, 8% of subjects in the Eperzan group discontinued active treatment because of an adverse event compared with 6% in the all comparators group.
Danish: I kliniske studier af mindst 2 års varighed fik 8 % af personerne i Eperzan-gruppen seponeret aktiv behandling på grund af en bivirkning sammenlignet med 6 % i komparatorgruppen (alle komparatorer).
English: Figure Q Figure R
Danish: Figur Q Figur R
English: You may feel the pain going from your front (abdomen) through to your back.
Danish: Du kan måske føle, at smerterne går fra forsiden (maven) og
English: This mixes the diluent in the rear chamber of the cartridge with the lyophilised powder in the front chamber.
Danish: Herved blandes solvensen i det bageste kammer af cylinderampullen med det frysetørrede pulver i det forreste kammer.
English: Do not dispose of the used pen in the household waste.
Danish: Smid ikke den brugte pen i skraldespanden.
English: DO NOT use if the pen is expired or shows the incorrect dose.
Danish: DU MÅ IKKE bruge den, hvis udløbsdatoen er overskredet eller viser forkert dosis.
English: Severe hypoglycaemia requiring the assistance of another person for treatment occurred uncommonly: 0.3% among patients receiving Eperzan and 0.4% among patients receiving a comparator.
Danish: Svær hypoglykæmi, der krævede behandling med hjælp fra en anden person, forekom sjældent: 0,3 % hos patienter, der fik Eperzan, og 0,4 % hos patienter, der fik en komparator.
English: IMPORTANT: Make sure you do not twist the pen to [3] until you have attached the needle in step 5.
Danish: VIGITGT: Vær sikker på, at du ikke drejer pennen til [3], før du har sat nålen på i trin 5.
English: Injection Button*
Danish: Injektionsknap*
English: In both the Eperzan and all comparator groups, patients with events were generally male, older, or had renal impairment.
Danish: I både Eperzan-gruppen og komparatorgrupperne optrådte bivirkningen generelt hos mænd, ældre eller personer med nedsat nyrefunktion.
English: The mean apparent clearance of albiglutide is 67 ml/h with an elimination half-life of approximately 5 days based on estimations from the population PK analyses from phase III patient studies and measured values.
Danish: Den gennemsnitlige tilsyneladende clearance af albiglutid er 67 ml/t med en eliminationshalveringstid på ca. 5 dage baseret på estimationer fra populationsfarmakokinetiske analyser fra fase III-patient-studier og målte værdier.
English: If you have questions or do not understand how to use your pen, talk to your doctor, nurse or pharmacist.
Danish: Hvis du har spørgsmål eller ikke forstår hvordan du skal bruge pennen, så tal med lægen, sygeplejersken eller apotekspersonalet.
English: Durability of glycaemic control
Danish: Varighed af glykæmisk kontrol
English: This means the needle is attached (Figure M).
Danish: Dette betyder, at nålen sidder, som den skal (Figur M).
English: DO NOT shake the pen to avoid foaming, which may affect your dose.
Danish: DU MÅ IKKE ryste pennen, da det kan medføre dannelse af skum, som kan påvirke din dosis.
English: Caution should be exercised in patients with a history of pancreatitis.
Danish: Der skal udvises forsigtighed hos patienter med pancreatitis i anamnesen.
English: At Week 156, 77% of patients treated with Eperzan were uptitrated to 50 mg SC weekly.
Danish: Ved uge 156 var 77 % af patienterne i Eperzan-armen optitreret til 50 mg s.c. ugentligt.
English: UNIQUE IDENTIFIER - 2D BARCODE 2D barcode carrying the unique identifier included.
Danish: ENTYDIG IDENTIFIKATOR - 2D STREGKODE Der er anført en 2D-stregkode, som indeholder en entydig identifikator.
English: The change from baseline in weight for Eperzan did not differ significantly from placebo but was significantly less compared to pioglitazone (see Table 5).
Danish: For Eperzan var ændringen i vægt i forhold til baseline ikke signifikant forskellig fra placebo, men var signifikant mindre sammenlignet med pioglitazon (se tabel 5).
English: Increased mortality and morbidity were seen at all doses (1 mg/kg/day) in lactating females in mouse preand postnatal development studies.
Danish: Der blev set øget mortalitet og morbiditet ved alle doser ( 1 mg/kg/dag) hos diegivende hunner i studier af den præ- og postnatale udvikling hos mus.
English: If you think this applies to you, don't use Eperzan until you have checked with your doctor, nurse or pharmacist.
Danish: Hvis du tror, at dette gælder for dig, må du ikke tage Eperzan, før du har talt med lægen, sundhedspersonalet eller apotekspersonalet.
English: IMPORTANT: Make sure you have waited 30 minutes before continuing onto step 4.
Danish: VIGITGT: Vær sikker på, at du har ventet 30 minutter før du fortsætter til trin 4.
English: Eperzan comes in a pen injector that you can inject yourself.
Danish: Eperzan fås i en injektionspen, og du kan injicere dig selv.
English: With the clear cartridge pointing up, gently swirl the pen for one minute.
Danish: Lad den gennemsigtige cylinderampul pege opad og roter forsigtigt pennen i ét minut.
English: The efficacy of Eperzan was evaluated in a randomised, double-blind, active-controlled 52-week study in 486 patients with mild, moderate, and severe renal impairment inadequately controlled on a current regimen of diet and exercise or other antidiabetic therapy.
Danish: Effekten af Eperzan blev vurderet i et randomiseret, dobbeltblindet, aktivt kontrolleret studie af 52 ugers varighed hos 486 patienter med let, moderat og svært nedsat nyrefunktion, der ikke var tilstrækkeligt kontrolleret med et aktuelt regimen med kost og motion eller anden antidiabetisk behandling.
English: What if I leave my pen with the needle attached (Step 5), and then come back to finish the next step much later?
Danish: Hvad sker der, hvis jeg lader min pen ligge med nålen på ved (trin 5), og derefter kommer tilbage meget senere for at gennemføre næste trin?
English: After mixing, wait 30 minutes before injection
Danish: Efter sammenblanding, vent 30 minutter før injektion.
English: The durability of glycaemic control for Eperzan over time relative to other classes of type 2 antidiabetic agents and placebo is shown in Figure 1 as add-on to metformin.
Danish: Varigheden af glykæmisk kontrol med Eperzan som funktion af tiden i forhold til andre klasser af type 2antidiabetika og placebo (som tillæg til metformin) er vist i figur 1.
English: 6a With needle pointing up, gently tap the clear cartridge 2-3 times to bring large air bubbles to the top (Figure N).
Danish: 6a Lad nålen pege opad, og bank let på den gennemsigtige cylinderampul 2-3 gange for at få de store luftbobler op til toppen (Figur N).
English: If you stop using Eperzan, your blood sugar levels may be affected.
Danish: Hvis du stopper med at tage Eperzan, kan det påvirke dit blodsukker.
English: In addition, a clinical pharmacology study showed a similar increased exposure for patients with moderate or severe renal impairment or those on haemodialysis relative to patients without renal impairment.
Danish: Endvidere viste et klinisk farmakologisk studie en tilsvarende øget eksponering hos patienter med moderat eller svært nedsat nyrefunktion og hos patienter i hæmodialysebehandling i forhold til patienter uden nedsat nyrefunktion.
English: Frequency categories below reflect combined data for the 2 doses of Eperzan, 30 mg or 50 mg weekly subcutaneously.
Danish: Nedenstående hyppighedskategorier afspejler kombinerede data for de 2 Eperzandoser - 30 mg eller 50 mg ugentligt subkutant.
English: The rate of symptomatic hypoglycaemia was higher for Eperzan when used in combination with a sulphonylurea (15% to 22%) or with insulin (18%) compared to combinations not including a sulphonylurea or insulin (1% to 4%).
Danish: Hyppigheden af symptomatisk hypoglykæmi var højere for Eperzan, når det blev anvendt i kombination med et sulfonylurinstof (15 % til 22 %) eller med insulin (18 %) sammenlignet med kombinationer uden et sulfonylurinstof eller insulin (1 % til 4 %).
English: When Eperzan was used as monotherapy, the incidence of symptomatic hypoglycaemia (<3.9 mmol/l) was similar for Eperzan 30 mg (2%), Eperzan 50 mg (1%) and placebo (3%).
Danish: Når Eperzan blev anvendt som monoterapi, var incidensen af symptomatisk hypoglykæmi (< 3,9 mmol/l) af samme størrelsesorden for Eperzan 30 mg (2 %), Eperzan 50 mg (1 %) og placebo (3 %).
English: 7c Place both needle caps into a container for pen disposal.
Danish: 7c Læg begge nålehætter ned i en beholder til den brugte pen.
English: In patients with type 2 diabetes who received 2 doses of albiglutide 32 mg (Day 1 and 8), a statistically significant reduction (24%) in postprandial glucose AUC(0.5-4.5 h) was observed compared to placebo following a standardised breakfast meal on Day 9.
Danish: Hos patienter med type 2-diabetes, der fik 2 doser af albiglutid på 32 mg (dag 1 og 8), blev der observeret en statistisk signifikant reduktion (24 %) i AUC(0,5-45 t) i postprandial glucose sammenlignet med placebo efter et standardiseret morgenmåltid på dag 9.
English: There is limited experience of albiglutide when combined with thiazolidinediones alone, sulphonylureas + thiazolidinediones, and metformin + sulphonylureas + thiazolidinediones.
Danish: Der er begrænset erfaring med albiglutid i kombination med thiazolidindion alene, sulfonylurinstof + thiazolidindion og med metformin + sulfonylurinstof + thiazolidindion.
English: Over 2,300 patients have received Eperzan in 8 placebo- or active-controlled phase III studies.
Danish: Sammendrag af sikkerhedsprofilen Over 2.300 patienter har fået Eperzan i 8 placebo-kontrollerede eller aktivt kontrollerede fase III-studier.
English: Lift Pen from Skin
Danish: Løft pennen fra huden
English: Albiglutide (50 mg weekly at steady-state) had no clinically relevant effects on the steady-state pharmacokinetics of a combination oral contraceptive containing norethindrone 0.5 mg and ethinyl estradiol 0.035 mg.
Danish: Albiglutid (50 mg ugentligt ved steady state) havde ingen klinisk relevant effekt på steady statefarmakokinetikken af et oralt kombinationskontraceptivum, som indeholdt 0,5 mg norethindron og 0,035 mg ethinylestradiol.
English: • A clean empty cup (Figure C).
Danish: • Et rent tomt bæger (Figur C).
English: Increased serum calcitonin levels have been associated with the thyroid C-cell hyperplasia and tumours observed in rodent studies with these other agents.
Danish: Forhøjede serum-calcitonin-niveauer er blevet associeret med thyreoidea-Ccelle-hyperplasi og tumorer observeret i studier med disse andre stoffer hos gnavere.
English: The incidence of pancreatitis (adjudicated as likely to be related to therapy) in the clinical studies was 0.3% for Eperzan compared to 0% for placebo and 0.1% for comparators (i.e. liraglutide, pioglitazone, glimepiride, sitagliptin, and insulin glargine) with or without additional background antidiabetic therapy (e.g. metformin).
Danish: Incidensen af pancreatitis (bedømt som sandsynligvis værende relateret til behandlingen) i de kliniske studier var 0,3 % for Eperzan sammenlignet med 0 % for placebo og 0,1 % for komparatorer (f.eks. liraglutid, pioglitazon, glimepirid, sitagliptin og insulin glargin) med eller uden yderligere antidiabetisk baggrundsbehandling (f.eks. metformin).
English: There have been no studies in patients with hepatic impairment (see section 5.2).
Danish: Der er ikke udført studier hos patienter med nedsat leverfunktion (se pkt.
English: IMPORTANT: Make sure you have waited 15 minutes before continuing onto step 4.
Danish: VIGITGT: Vær sikker på, at du har ventet 15 minutter før du fortsætter til trin 4.
English: In a thorough QT study in healthy subjects, an increase in heart rate (6 to 8 bpm) was observed after repeat dosing with albiglutide 50 mg compared to baseline values.
Danish: I et omfattende QT-studie med raske forsøgspersoner blev der observeret en stigning i hjertefrekvensen (6 til 8 bpm) efter gentagen dosering af albiglutid 50 mg sammenlignet med baseline-værdier.
English: The table presents the adverse reactions that occurred more frequently among patients treated with Eperzan than patients treated with all comparators.
Danish: Tabellen viser de bivirkninger, som forekom hyppigere blandt patienter, der blev behandlet med Eperzan, end blandt patienter, der blev behandlet med komparator (alle komparatorer).
English: Do not use this medicine after the expiry date which is stated on the pen and the carton after ‘EXP'.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på pennen og kartonen efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: 9b Immediately put the pen (with needle attached) in a container for pen disposal.
Danish: 9b Du skal med det samme lægge pennen (med nålen på) i en beholder til den brugte pen.
English: No clinical studies were conducted to examine the effects of hepatic impairment on the pharmacokinetics of Eperzan.
Danish: Der blev ikke udført kliniske studier med henblik på at undersøge effekten af nedsat leverfunktion på Eperzans farmakokinetik.
English: Patients were randomised (1:1:1) to Eperzan 30 mg once weekly, Eperzan 30 mg once weekly uptitrated to 50 mg once weekly at week 12, or placebo.
Danish: Patienterne blev randomiseret (1:1:1) til Eperzan 30 mg én gang ugentligt, Eperzan 30 mg én gang ugentligt øget til 50 mg én gang ugentligt ved uge 12 eller placebo.
English: If you have attached the needle, EPERZAN should be used right away.
Danish: Hvis nålen er sat på, skal ESPERZAN bruges med det samme.
English: Cardiovascular Evaluation:
Danish: Kardiovaskulær evaluering
English: Baseline (mean)
Danish: Baseline (middel)
English: ATTACHING NEEDLE, REMOVING AIR FROM CARTRIDGE, AND PREPARING PEN FOR INJECTION (STEPS 5-7)
Danish: SÆT NÅLEN PÅ, FJERN LUFT FRA CYLINDERAMPULLEN OG KLARGØR PENNEN TIL INJEKTION (TRIN 5-7)
English: Albiglutide
Danish: Albiglutid
English: INFORMATION IN BRAILLE eperzan 50
Danish: INFORMATION I BRAILLESKRIFT eperzan 50
English: For liquids, gastric emptying t1/2 increased from 0.28 h to 0.69 h (p=0.0018).
Danish: For væsker steg t1/2 for ventrikeltømning fra 0,28 t til 0,69 t (p = 0,0018).
English: If it is more than 3 days since you missed your dose, wait until your usually scheduled day for your next injection.
Danish: Hvis der er gået mere end 3 dage, siden du glemte din dosis, så vent med at tage næste dosis til den sædvanlige ugedag.
English: Fertility For both men and women, it is not known if Eperzan could affect your fertility.
Danish: Frugtbarhed Det vides ikke, om Eperzan kan påvirke din frugtbarhed.
English: Offspring of mice dosed with 50 mg/kg/day during organogenesis had reduced weight during the pre-weaning period (which recovered after weaning), dehydration and coldness, and a delay in balanopreputial separation.
Danish: Afkom fra mus, der blev doseret med 50 mg/kg/dag under organogenesen, havde nedsat vægt i perioden før afvænning (blev normaliseret efter afvænning), var dehydrerede og kolde og udviste en forsinkelse i balano-præputial separation.
English: 8c After hearing the “click,” continue holding down the injection button and slowly count to 5 to deliver the full dose of medicine (Figure T).
Danish: 8c Efter du hører ”klikket”, skal du blive ved med at holde injektionsknappen nede, og tæl herefter langsomt til 5 for at få den fulde dosis af lægemidlet (Figur T).
English: As albiglutide is an albumin fusion molecule, plasma protein binding has not been assessed.
Danish: Da albiglutid er et albumin-fusionsmolekyle, er bindingen til plasmaproteiner ikke bestemt.
English: Placebo Sitagliptin Glimepiride Albiglutide x axis; Weeks (Rescue free), y axis; Probability of event
Danish: Placebo Sitagliptin Glimepiride Albiglutide x-akse: uger (uden nødmedicinering), y-akse: sandsynlighed for hændelse.
English: REMOVING BOTH NEEDLE CAPS AND INJECTING YOUR MEDICINE (STEPS 7-8) After I turn the pen to Number 3 (Step 6), there are still some small air bubbles remaining.
Danish: FJERN BEGGE NÅLEHÆTTER OG INJICÉR MEDICINEN (TRIN 7-8) Der er stadig nogle små luftbobler tilbage, efter jeg har drejet pennen til tallet 3 (trin 6).
English: • allergic reaction (hypersensitivity); this includes symptoms such as local or widespread rash, redness or itching of the skin and difficulty breathing (also see ‘Conditions you need to look out for' at the
Danish: • allergisk reaktion (overfølsomhed); dette omfatter symptomer som lokalt eller udbredt udslæt, rødme eller kløe i huden og åndedrætsbesvær (se også ”Forhold du skal være opmærksom på” i begyndelse af
English: However, in healthy volunteers following 50 mg the steady state concentration was 7.39 µg/ml at day 36, thus higher than population PK analyses from phase III patient studies predicted.
Danish: Hos raske frivillige var steady state-koncentrationen efter 50 mg dog 7,36 µg/ml ved dag 36 og dermed højere end beregnet ud fra populationsfarmakokinetiske analyser fra fase III-patient-studier.
English: • low blood sugar (hypoglycaemia) if you use Eperzan on its own or in combination with metformin or pioglitazone
Danish: • for lavt blodsukker (hypoglykæmi), hvis du tager Eperzan alene eller i kombination med metformin eller pioglitazon
English: INFORMATION IN BRAILLE eperzan 30
Danish: INFORMATION I BRAILLESKRIFT eperzan 30
English: A single dose of simvastatin (80 mg) was administered with steady-state albiglutide (50 mg weekly).
Danish: En enkelt dosis simvastatin (80 mg) blev administreret ved steady state-albiglutid (50 mg ugentligt).
English: • heartburn (gastro-oesophageal reflux)
Danish: • halsbrand (gastroøsofageal refluks).
English: • if you are taking a sulphonylurea or insulin for your diabetes, as low blood sugar (hypoglycaemia) can occur.
Danish: • hvis du tager et sulfonylurinstof eller insulin mod din diabetes, da du i givet fald kan få for lavt blodsukker (hypoglykæmi).
English: Baseline (mean) Change at Week 52b
Danish: Baseline (middel) Ændring ved uge 52b
English: Use immediately after needle is attached.
Danish: Skal anvendes omgående, når nålen er påsat.
English: Step 3 Wait 15 minutes
Danish: Trin 3 Vent 15 minutter
English: If you forget to use Eperzan
Danish: Hvis du har glemt at tage Eperzan
English: It is not known if Eperzan passes into your breast milk.
Danish: Det vides ikke, om Eperzan går over i mælken.
English: The most serious adverse reaction in clinical trials was acute pancreatitis (see section 4.4).
Danish: Den alvorligste bivirkning i de kliniske studier var akut pancreatitis (se pkt.
English: MIXING YOUR MEDICINE AND WAITING 30 MINUTES (STEPS 2-3) What if I do not wait 30 minutes after turning the pen to the Number 2?
Danish: BLANDING AF MEDICINEN OG VENTETID I 30 MINUTTER (TRIN 2-3) Hvad sker der, hvis jeg ikke venter 30 minutter efter at have drejet pennen til tallet 2?
English: Follow instructions to twist the cartridge until ‘2' appears in the number window and a “click” is heard.
Danish: Følg vejledningen og drej cylinderampullen, indtil ‘2' viser sig i nummervinduet, og der høres et "klik".
English: Insulin lispro Insulin glargine ( 20 units per day)
Danish: Insulin lispro insulin glargin ( 20 enheder pr. dag)
English: Patients with severe renal impairment receiving Eperzan experienced a higher frequency of diarrhoea, nausea, and vomiting compared to patients with mild or moderate renal impairment.
Danish: Patienter med svært nedsat nyrefunktion, som fik Eperzan, oplevede en større hyppighed af diarré, kvalme og opkastning sammenlignet med patienter med let til moderat nedsat nyrefunktion.
English: If you do not push the needle on completely, the pen may jam or leak.
Danish: Hvis du ikke trykker nålen ordentligt på, kan pennen blokere eller blive utæt.
English: Step 4 Rock Pen and Check Medicine
Danish: Trin 4 Vip pennen og undersøg medicinen
English: Add-on to metformin plus sulphonylurea
Danish: Som tillæg til metformin plus sulfonylurinstof
English: Studies evaluated the use of Eperzan 30 mg and 50 mg once weekly, allowing for optional titration of Eperzan from 30 mg to 50 mg once weekly in 5 of the 8 studies.
Danish: I studierne blev der foretaget en vurdering af Eperzan 30 mg og 50 mg én gang ugentligt, idet der var mulighed for valgfri øgning af Eperzan fra 30 mg til 50 mg én gang ugentligt i 5 af de 8 studier.