FrancophonIA/ELRC3.0 huggingface dataset:
English: Mild and transient diarrhoea, soft faeces or vomiting were commonly reported in clinical trials with treatment up to 6 days.
Danish: Mild og forbigående diarré, blød afføring eller opkastning var almindelige bivirkninger rapporteret i kliniske forsøg med behandling i op til 6 dage.
English: After a dosage of 2 mg/kg a Tmax of 1 h (cats and dogs), a Cmax of 1,464 ng/ml (cats) and 615 ng/ml (dogs), and an AUC of 3,128 ng·h/ml (cats) and 2,180 ng·h/ml (dogs) is obtained.
Danish: Efter en dosis på 2 mg/kg opnås en Tmax på 1 t. (katte og hunde), en Cmax på 1.464 ng/ml (katte) og 615 ng/ml (hunde) samt AUC på 3.128 ng.t./ml (katte) og 2.180 ng.t./ml (hunde).
English: 7 tablets 14 tablets 28 tablets 70 tablets 30 x 1 tablets 60 x 1 tablets
Danish: 7 tabletter 14 tabletter 28 tabletter 70 tabletter 30 x 1 tabletter 60 x 1 tabletter
English: (IC50 0.04 μM) as compared to COX-1 (IC50 7.9 μM).
Danish: 0,04 μM) som for COX-1 (IC50 7,9 μM).
English: No relevant effects on body weight, bleeding time or evidence of any gastrointestinal, kidney or liver toxicity were observed.
Danish: Der blev ikke set nogen relevant effekt på legemsvægt eller blødningstid eller tegn på toksicitet i mave-tarm-kanal, nyrer eller lever.
English: In artificially induced inflammation in cats and dogs, robenacoxib reduced pain, inflammation and fever at the recommended doses with a rapid onset of action (1 h).
Danish: Ved kunstig fremkaldt betændelse i katte og hunde reducerede robenacoxib smerter, betændelse og feber ved den anbefalede dosis og med en hurtig virkning (1 t).
English: 6 x 1 tablets 12 x 1tablets 30 x 1 tablets 60 x 1 tablets
Danish: 6 x 1 tabletter 12 x 1 tabletter 30 x 1 tabletter 60 x 1 tabletter
English: Vomiting and soft faeces were very common, decreased appetite and diarrhoea were common, and blood in the faeces was uncommon.
Danish: Opkastning og blød afføring er meget almindelig, nedsat appetit og diarré er almindelig, og blod i afføringen er ikke almindelig.
English: Multi-dose amber glass vial containing 20 ml solution for injection, closed with a rubber stopper and sealed with an aluminium cap. One vial packed in a cardboard box.
Danish: Brunt flerdosis hætteglas indeholdende 20 ml injektionsopløsning, lukket med en gummiprop og forseglet med en aluminiumshætte.
English: Acute musculoskeletal disorders: treat for up to 6 days.
Danish: Behandling af akutte muskuloskeletale sygdomme: op til 6 dage.
English: Number of tablets by size
Danish: Antal tabletter ud fra størrelse
English: Treatment should be discontinued after 6 weeks if no clinical improvement is apparent.
Danish: Behandling bør stoppes efter 6 uger, hvis der ikke ses nogen klinisk forbedring.
English: Onsior must not be administered in conjunction with other NSAIDs.
Danish: Onsior må ikke administreres samtidig med andre NSAID'er.
English: In most cases the liver enzyme activities either stabilised or decreased with continued treatment.
Danish: I de fleste tilfælde stabiliseredes eller faldt aktiviteten af leverenzymer ved fortsat behandling.
English: Onsior 5 mg Onsior 10 mg Onsior 20 mg Onsior 40 mg
Danish: Onsior 5 mg Onsior 10 mg Onsior 20 mg Onsior 40 mg Robenacoxib
English: As anaesthetics may affect renal perfusion, the use of parenteral fluid therapy during surgery should be considered to decrease potential renal complications when using NSAIDs peri-operatively.
Danish: Da anæstetika kan påvirke den renale perfusion, bør det overvejes at anvende parenteral væsketerapi under operationer for at reducere potentielle nyrekomplikationer, når NSAID'er anvendes perioperativt.
English: The following number of tablets should be given once daily at the same time every day.
Danish: Nedenfor nævnte antal tabletter bør indgives 1 gang dagligt på samme tid hver dag.
English: Tablets:
Danish: Tabletter:
English: Treatment should be discontinued after 10 days if no clinical improvement is apparent.
Danish: Behandling bør stoppes efter 10 dage, hvis en klinisk forbedring ikke er tydelig.
English: In small children, accidental ingestion increases the risk for NSAID adverse effects.
Danish: Utilsigtet indgift hos små børn forøger risikoen for bivirkninger som følge af NSAID.
English: MARKETING AUTHORISATION NUMBER(S)
Danish: MARKEDSFØRINGSTILLADELSENSNUMMER (NUMRE)
English: Each tablet contains 5 mg Robenacoxib Each tablet contains 10 mg Robenacoxib Each tablet contains 20 mg Robenacoxib Each tablet contains 40 mg Robenacoxib
Danish: Hver tablet indeholder 5 mg Robenacoxib Hver tablet indeholder 10 mg Robenacoxib Hver tablet indeholder 20 mg Robenacoxib Hver tablet indeholder 40 mg Robenacoxib
English: 20 to < 40
Danish: 20 til < 40
English: In the high dose group kidney weights were decreased and sporadically associated with renal tubular degeneration/ regeneration but not correlated with evidence of renal dysfunction on clinical pathology parameters.
Danish: I højdosisgruppen faldt nyrevægten, og den var sporadisk forbundet med renal tubulær degeneration/regeneration, men var ikke korreleret med evidens for renal dysfunktion i kliniske patologiparametre.
English: At the recommended dosage (2 mg/kg), analgesic, anti-inflammatory and anti-pyretic effects were demonstrated in an inflammation model, and in clinical trials, robenacoxib reduced pain and inflammation in cats undergoing orthopaedic or soft tissue surgery.
Danish: Ved den anbefalede dosis (2 mg/kg) demonstreredes analgetisk, antiinflammatorisk og antipyretisk effekt i en antiinflammationsmodel, og i kliniske forsøg reducerede robenacoxib smerter og inflammation hos katte, der fik foretaget ortopæd- eller bløddelskirurgi.
English: At a dose of 1-2 mg/kg body weight, robenacoxib tablets produced a marked inhibition of COX-2 activity in cats and had no effect on COX-1 activity.
Danish: Ved en dosis på 1 - 2 mg/kg legemsvægt gav robenacoxib tabletter en markant hæmning af COX-2-aktiviteten hos katte og havde ingen virkning på COX-1-aktiviteten.
English: Concomitant treatment with medicines displaying action on renal flow, e.g. diuretics or angiotensin converting enzyme (ACE) inhibitors, should be subject to clinical monitoring.
Danish: Samtidig behandling med medicin, der påvirker det renale flow som f.eks. diuretika eller angiotensin converting enzyme (ACE) hæmmere, bør monitoreres klinisk.
English: STATEMENT OF ACTIVE SUBSTANCES Each tablet contains 6 mg Robenacoxib
Danish: ANGIVELSE AF AKTIVE STOFFER Hver tablet indeholder 6 mg Robenacoxib
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS NATURE/TYPE: Glass vial
Danish: MINDSTEKRAV TIL OPLYSNINGER PÅ SMÅ INDRE PAKNINGER ART/TYPE: Hætteglas af glas
English: Robenacoxib is excreted predominantly via the biliary route (∼70%) rather than via the kidneys (∼30%).
Danish: Robenacoxib udskilles overvejende biliært (∼70%) snarere end via nyrerne (∼30%).
English: Co-administration of robenacoxib non-flavoured tablets with food produced no delay in Tmax, but slightly lower values for Cmax (832 ng/ml) and AUC (782 ng·h/ml).
Danish: Indgift af robenacoxib tabletter uden tilsætning af smagsstof med mad gav ikke nogen forsinkelse i Tmax, men lidt lavere værdier for Cmax (832 ng/ml) og AUC (782 ng.t./ml).
English: In healthy cats treated with or without the diuretic furosemide, concomitant administration of Onsior with the ACE inhibitor benazepril for 7 days was not associated with any negative effects on plasma aldosterone concentrations, plasma renin activity or glomerular filtration rate.
Danish: Hos raske katte behandlet med eller uden vanddrivende furosemid var samtidig administration af Onsior og ACE-hæmmeren benazepril i 7 dage ikke forbundet med nogen negative virkninger på plasmakoncentrationen af aldosteron, plasmareninaktiviteten eller den glomerulære filtrationsrate.
English: 10 to < 20
Danish: 10 til < 20
English: Increases in liver enzyme activities associated with clinical signs of anorexia, apathy or vomiting were uncommon.
Danish: Stigninger i aktiviteten af leverenzymer forbundet med kliniske tegn på anoreksi, apati eller opkastning var ikke almindeligt.
English: If use cannot be avoided, these animals require careful monitoring and fluid therapy.
Danish: Hvis anvendelse ikke kan undgås, kræver disse dyr omhyggelig monitorering og væsketerapi.
English: In an inflammation model in cats, robenacoxib injection had analgesic, anti-inflammatory and anti-pyretic effects and a rapid onset of action (0.5 h).
Danish: I en inflammationsmodel hos katte havde injektion af robenacoxib analgetiske, antiinflammatoriske og antipyretiske virkninger og hurtig indsættende virkning (0,5 t.).
English: Robenacoxib is excreted predominantly via the biliary route in cats (∼70%) and dogs (∼65%) and the remainder via the kidneys.
Danish: Robenacoxib udskilles overvejende biliært hos katte (∼70 %) og hunde (∼65 %) og resten via nyrerne.
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS NATURE/TYPE: Blister foil
Danish: MINDSTEKRAV TIL OPLYSNINGER PÅ BLISTERKORT ELLER BLISTERSTRIPS ART/TYPE: Blisterfolie
English: Slight pain at injection site was commonly reported.
Danish: Lette smerter på injektionsstedet var almindeligt rapporteret.
English: Repeated subcutaneous administration at dosages of 2-20 mg/kg produced no change in the blood profile, with neither bioaccumulation of robenacoxib nor enzyme induction.
Danish: Gentagen subkutan indgift i doser på 2-20 mg/kg forårsagede ingen ændring i blodprofilen, hverken bioakkumulation af robenacoxib eller enzyminduktion.
English: The interchangeable use of Onsior tablets and Onsior solution for injection in 4-months old cats at overdoses of up to 3 times the maximum recommended dose (2.4 mg, 4.8 mg, 7.2 mg robenacoxib/kg orally and 2.0 mg, 4.0 mg and 6.0 mg robenacoxib/kg subcutaneously) resulted in a dose-dependent increase of sporadic oedema at the injection site and minimal to mild subacute/chronic inflammation of the subcutaneous tissue.
Danish: Skiftevis brug af Onsior tabletter og Onsior injektionsvæske, opløsning hos 4 måneder gamle katte med overdoser på op til 3 gange den maksimalt anbefalede dosis (2,4 mg, 4,8 mg, 7,2 mg robenacoxib/kg oralt og 2,0 mg, 4,0 mg og 6,0 mg robenacoxib/kg subkutant) resulterede i en dosisafhængig stigning i sporadisk ødem på injektionsstedet og minimal til mild subakut/kronisk inflammation af det subkutane væv.
English: At dosages ranging from 0.25 to 4 mg/kg, robenacoxib had analgesic, anti-inflammatory and anti-pyretic effects in an inflammation model with a rapid onset of action (1 h).
Danish: Ved doser fra 0,25 til 4 mg/kg havde robenacoxib analgetisk, antiinflammatorisk og antipyretisk effekt i en antiinflammationsmodel med en hurtigt indsættende virkning (1 t).
English: WITHDRAWAL PERIOD(S) Not applicable
Danish: TILBAGEHOLDELSESTID(ER) Ikke relevant
English: Pain at injection site was commonly reported.
Danish: Smerter på injektionsstedet var almindeligt rapporteret.
English: STATEMENT OF THE ACTIVE SUBSTANCE(S) AND OTHER INGREDIENT(S) Each tablet contains the following amount of robenacoxib and bears the imprint “NA” on one side and the following imprint on the other side:
Danish: ANGIVELSE AF DET AKTIVE STOF OG ANDRE INDHOLDSSTOFFER Hver tablet indeholder følgende mængde robenacoxib og har mærkning NA på den ene side og følgende mærkning på den anden side:
English: Vomiting was very commonly reported, and anorexia, diarrhoea, lethargy and inappropriate defecation were commonly reported in field studies with treatment up to 3 months in cats with chronic musculo-skeletal disorder, with similar frequencies in the Onsior and placebo treated cats.
Danish: Opkastning er rapporteret som meget almindelig, og anoreksi, diarré, sløvhed og upassende afføring er rapporteret som almindelig i feltstudier med behandling i op til 3 måneder af katte med kroniske muskuloskeletale sygdomme, med samme hyppigheder hos Onsior- og placebobehandlede katte.
English: Vomiting was very commonly reported, and anorexia, diarrhoea, lethargy and inappropriate defecation were commonly reported in field studies with treatment up to 12 weeks in cats with chronic musculo-skeletal disorder, with similar frequencies in the Onsior and placebo treated cats.
Danish: Opkastning er rapporteret som meget almindelig, og anoreksi, diarré, letargi og upassende afføring er rapporteret som almindelig i feltstudier med behandling i op til 12 uger af katte med kroniske muskuloskeletale sygdomme, med samme hyppigheder hos Onsior- og placebobehandlede katte.
English: In dogs treated up to 2 weeks no increases in liver enzyme activities were observed.
Danish: Der blev ikke observeret nogen stigning i aktiviteten af leverenzymer hos hunde behandlet i op til 2 uger.
English: Administer the solution subcutaneously to cats or dogs approximately 30 minutes before the start of surgery, for example around the time of induction of general anaesthesia, at a dose of 1 ml per 10 kg of body weight (2 mg/kg).
Danish: Indgiv opløsningen subkutant til katte eller hunde ca. 30 minutter før påbegyndelse af operation, f.eks. omkring tidspunktet for indgift af generel anæstesi, i en dosis på 1 ml pr. 10 kg legemsvægt (2 mg/kg).
English: Do not use in case of hypersensitivity to robenacoxib or to any of the ingredients of the tablets.
Danish: Må ikke anvendes i tilfælde af overfølsomhed over for robenacoxib eller nogen af bestanddelene i tabletterne.
English: In clinical trials at the recommended dose (2 mg/kg), robenacoxib reduced pain and inflammation in dogs undergoing orthopaedic or soft tissue surgery.
Danish: I kliniske forsøg med den anbefalede dosis (2 mg/kg), reducerede robenacoxib smerter og inflammation hos hunde, der fik foretaget ortopæd- eller bløddelskirurgi.
English: Do not use concomitantly with corticosteroids or other non-steroidal anti-inflammatory drugs (NSAIDs).
Danish: Bør ikke anvendes samtidig med kortikosteroider eller andre non-steroide antiinflammatoriske lægemidler (NSAID'er).
English: In case of accidental ingestion or self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Danish: I tilfælde af utilsigtet indgift eller selvinjektion skal der straks søges lægehjælp, og indlægssedlen eller etiketten bør vises til lægen.
English: COX-2 activity and had no effect on COX-1 activity in dogs at oral doses ranging from 0.5 to 4 mg/kg.
Danish: Robenacoxib gav en markant hæmning af COX-2-aktiviteten og havde ingen virkning på COX-1-aktiviteten hos hunde ved perorale doser fra 0,5 til 4 mg/kg.
English: In clinical trials robenacoxib tablets reduced the lameness and inflammation of dogs with chronic osteoarthritis.
Danish: I kliniske forsøg reducerede robenacoxib-tabletter halten og inflammation hos hunde med kronisk osteoarthritis.
English: Diarrhoea or vomiting with blood were uncommon.
Danish: Diarré eller opkastning med blod er ikke almindeligt.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE NATURE/TYPE: Cardboard box
Danish: OPLYSNINGER, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE ART/TYPE: Papkarton
English: In vivo, robenacoxib solution for injection produced marked inhibition of COX-2 activity and had no effect on COX-1 activity.
Danish: In vivo gav robenacoxib-injektionsopløsning en markant hæmning af COX-2-aktiviteten og havde ingen virkning på COX-1-aktiviteten.
English: Yeast powder Cellulose, microcrystalline Povidone (K-30) Crospovidone Silica, colloidal anhydrous Magnesium stearate
Danish: Cellulose, mikrokrystallinsk Povidon (K-30) Crospovidon
English: Do not use in dogs suffering from stomach ulcer or with liver disease.
Danish: Bør ikke anvendes til hunde, der lider af mavesår eller leversygdom.
English: Robenacoxib is excreted predominantly via the biliary route (∼65%) and the remainder via the kidneys.
Danish: Robenacoxib udskilles overvejende biliært (∼65 %) og resten via nyrerne.
English: DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION The recommended dose of robenacoxib is 1 mg/kg body weight with a range 1-2 mg/kg.
Danish: DOSERING FOR HVER DYREART, ANVENDELSESMÅDE OG INDGIVELSESVEJ(E) Den anbefalede dosis af robenacoxib er 1 mg/kg legemsvægt med et interval på 1 - 2 mg/kg.
English: 5 to < 10
Danish: 5 til < 10
English: Administer subcutaneously to cats or dogs approximately 30 minutes before the start of surgery, for example around the time of induction of general anaesthesia, at a dose of 1 ml per 10 kg of body weight (2 mg/kg).
Danish: Indgives subkutant til katte eller hunde ca. 30 mintter før påbegyndelse af operation, f.eks. omkring tidspunktet for induktion af generel anæstesi, i en dosis på 1 ml pr. 10 kg legemsvægt (2 mg/kg).
English: Onsior 5 mg tablets for dogs Onsior 10 mg tablets for dogs Onsior 20 mg tablets for dogs Onsior 40 mg tablets for dogs
Danish: Onsior 5 mg tabletter til hunde Onsior 10 mg tabletter til hunde Onsior 20 mg tabletter til hunde Onsior 40 mg tabletter til hunde
English: Diarrhoea or vomiting with blood was uncommon.
Danish: Diarré og opkastning med blod var ikke almindeligt.
English: After oral administration of tablets, the terminal half-life from blood was 1.7 h. Robenacoxib persists longer and at higher concentrations at sites of inflammation than in blood.
Danish: Efter oral indgift af tabletter var den terminale halveringstid fra blod 1,7 t. Robenacoxib varer længere og har højere koncentrationer på steder med inflammation end i blodet.
English: After oral administration of the tablets, the terminal half-life in blood was 1.2 h. Robenacoxib persists longer and at higher concentrations at sites of inflammation than in blood.
Danish: Efter oral indgift af tabletterne var den terminale halveringstid i blod 1,2 t. Robenacoxib varer længere og har højere koncentrationer på steder med inflammation end i blodet.
English: Therapy should be discontinued if liver enzyme activities increase markedly or the dog shows clinical signs such as anorexia, apathy or vomiting in combination with elevated liver enzymes.
Danish: Behandlingen skal seponeres, hvis aktiviteten af leverenzymer stiger markant, eller hvis hunden viser kliniske tegn som anoreksi, apati eller opkastning i kombination med forhøjede leverenzymer.
English: Co-administration of robenacoxib tablets with one third of the daily food ration produced no change in Tmax (0.5 h), Cmax (1,201 ng/ml) or AUC (1383 ng·h/ml).
Danish: Indgift af robenacoxib tabletter samtidig med en tredjedel af den daglige madration gav ikke nogen ændring i Tmax (0,5 t.), Cmax (1.201 ng/ml) eller AUC (1.383 ng.t./ml).
English: The pharmacokinetics of robenacoxib do not differ between male and female dogs, and are linear over the range 0.5-8 mg/kg.
Danish: Farmakokinetikken af robenacoxib er ikke forskellig hos han- og hunhunde og er lineær i intervallet 0,5-8 mg/kg.
English: In artificially induced inflammation in dogs, robenacoxib reduced pain and inflammation with single oral doses ranging from 0.5 to 8 mg/kg and a rapid onset of action (0.5 h).
Danish: Ved kunstig fremkaldt betændelse i hunde reducerede robenacoxib smerter og betændelse med enkelte, orale doser fra 0,5 til 8 mg/kg og med en hurtig virkning (0,5 t).
English: COX-2 is the inducible form of the enzyme which is responsible for the production of mediators including PGE2 which induce pain, inflammation or fever.
Danish: COX-2 er den inducerbare form af enzymet, som er ansvarlig for dannelsen af mediatorer, herunder PGE2, der inducerer smerter, inflammation eller feber.
English: If use cannot be avoided, these dogs require careful monitoring.
Danish: Hvis anvendelse ikke kan undgås, skal disse hunde monitoreres omhyggeligt.
English: Robenacoxib has a relatively small volume of distribution (Vss of 190 ml/kg in cats and 240 ml/kg in dogs) and is highly bound to plasma proteins (>99%).
Danish: Robenacoxib har et relativt lille fordelingsvolumen (Vss 190 ml/kg hos katte og 240 ml/kg hos hunde) og er i høj grad bundet til plasmaproteiner (> 99%).
English: COX-2 is the inducible form of the enzyme and is responsible for the production of mediators including PGE2 which induce pain, inflammation or fever.
Danish: COX-2 er den inducerbare form af enzymet og er ansvarlig for dannelsen af mediatorer, herunder PGE2, der inducerer smerter, inflammation eller feber.
English: Do not use together with non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, medicines commonly used in the treatment of pain, inflammation and allergies.
Danish: Må ikke anvendes sammen med smertestillende og betændelseshæmmende midler (NSAID'er) eller kortikosteroider, medicin som normalt anvendes til behandling af smerter, betændelse og allergier.
English: Therapy should be discontinued if liver enzyme activities increase markedly or the dog shows symptoms such as anorexia, apathy or vomiting in combination with elevated liver enzymes.
Danish: Behandlingen skal stoppes, hvis aktiviteten af leverenzymerne stiger markant, eller hvis hunden viser symptomer som appetitløshed, apati eller opkastning i kombination med forhøjede leverenzymer.
English: Robenacoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class.
Danish: Robenacoxib er et non-steroidt, antiinflammatorisk lægemiddel (NSAID), der tilhører coxib-gruppen.
English: The pharmacokinetics of robenacoxib injection do not differ between male and female cats and dogs, and are linear over the range of 0.25-4 mg/kg in dogs.
Danish: Farmakokinetikken af robenacoxib-injektion er ikke forskellig hos henholdsvis han- og hunkatte og han- og hunhunde og er lineær i intervallet 0,25-4 mg/kg hos hunde.
English: COX-1 is the constitutive form of the enzyme and has protective functions, e.g. in the gastrointestinal tract and kidneys.
Danish: COX-1 er grundformen af enzymet og har beskyttende funktioner, f.eks. i mave-tarmkanalen og nyrerne.
English: Do not use together with other non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, medicines commonly used in the treatment of pain, inflammation and allergies.
Danish: Må ikke anvendes sammen med andre smertestillende og betændelseshæmmende midler (NSAID'er) eller kortikosteroider, medicin som normalt anvendes til behandling af smerter, betændelse og allergier.
English: Elanco France S.A.S 26 Rue de la Chapelle 68330 Huningue FRANCE
Danish: Elanco France S.A.S 26 Rue de la Chapelle, F-68330 Huningue, Frankrig.
English: Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Danish: Bør ikke anvendes i tilfælde af overfølsomhed over for det aktive stof eller et eller flere af hjælpestofferne.
English: In clinical trials in cats, robenacoxib tablets reduced pain and inflammation associated with acute musculo-skeletal disorders and reduced the need for rescue treatment when given as premedication in case of orthopaedic surgery, in combination with opioids.
Danish: I kliniske forsøg med katte reducerede robenacoxib-tabletter smerter og inflammation forbundet med akutte muskuloskeletale sygdomme og nedsatte behovet for nødvendig supplerende behandling, når det blev givet som premedicinering ved ortopædkirurgi, i kombination med opioider.
English: INDICATION(S) For the treatment of pain and inflammation of chronic osteoarthritis in dogs.
Danish: INDIKATION(ER) Til behandling af smerter og betændelse ved kronisk slidgigt hos hunde.
English: It selectively inhibits the cyclooxygenase 2 enzyme (COX-2), which is responsible for pain, inflammation or fever.
Danish: Det hæmmer aktiviteten af enzymet cyklooxygenase-2 (COX-2), som forårsager smerte, betændelse eller feber.
English: If use cannot be avoided, these cats require careful monitoring.
Danish: Hvis anvendelse ikke kan undgås, skal disse katte overvåges omhyggeligt.
English: After oral administration of robenacoxib tablets at approximately 2 mg/kg without food, peak blood concentrations are attained rapidly with a Tmax of 0.5 h, a Cmax of 1,159 ng/ml and an AUC of 1,337 ng·h/ml.
Danish: Efter oral indgift af robenacoxib tabletter med ca. 2 mg/kg uden mad nås de højeste blodkoncentrationer hurtigt med en Tmax på 0,5 t., en Cmax på 1.159 ng/ml og AUC på 1.337 ng.t./ml.