FrancophonIA/ELRC3.0 huggingface dataset:
English: However, due to their transient nature, the incidence of antibodies detected at each assessment point was typically less than 7% in rheumatoid arthritis subjects and psoriasis subjects.
Croatian: Međutim, zbog njihove prolazne prirode, incidencija pojave protutijela otkrivenih u svakoj točki ocjenjivanja bila je u pravilu manja od 7% u bolesnika s reumatoidnim artritisom i bolesnika s psorijazom.
English: After discontinuation of LIFMIOR, symptoms of arthritis generally returned within a month.
Croatian: Općenito, nakon prekida liječenja LIFMIORom simptomi artritisa su se ponovno javili u roku od mjesec dana.
English: • Alcohol abuse: LIFMIOR should not be used for the treatment of hepatitis related to alcohol abuse.
Croatian: • Zloporaba alkohola: LIFMIOR se ne smije primjenjivati za liječenje hepatitisa povezanog s pretjeranom konzumacijom alkohola.
English: Autoantibody formation Treatment with LIFMIOR may result in the formation of autoimmune antibodies (see section 4.8).
Croatian: Stvaranje autoprotutijela Liječenje LIFMIORom može uzrokovati stvaranje autoimunih protutijela (vidjeti dio 4.8).
English: However, caution should be exercised when treating the elderly and particular attention paid with respect to occurrence of infections.
Croatian: Međutim, nužan je oprez pri liječenju starijih bolesnika te osobita pozornost s obzirom na pojavu infekcija.
English: The study evaluated 215 adult patients (modified intent-to-treat population) with active nr-AxSpa (18 to 49 years of age), defined as those patients meeting the ASAS classification criteria of axial spondyloarthritis but did not meet the modified New York criteria for AS.
Croatian: Ispitivanje je procijenilo 215 odraslih bolesnika (modificirana populacija s namjerom liječenja) s aktivnim nr-AxSpa (u dobi od 18 do 49 godina), koji su definirani kao oni bolesnici koji zadovoljavaju kriterije klasifikacije ASAS aksijalnog spondiloartritisa, ali nisu zadovoljili modificirane New York kriterije za AS.
English: Chemical and physical in-use stability has been demonstrated for 6 hours at temperatures of up to 25°C after reconstitution.
Croatian: Dokazana je kemijska i fizikalna stabilnost u trajanju od 6 sati na temperaturi do 25C nakon rekonstitucije.
English: The results of this controlled trial were expressed in percentage improvement in rheumatoid arthritis using American College of Rheumatology (ACR) response criteria.
Croatian: Rezultati ovog kontroliranog ispitivanja izraženi su postotkom poboljšanja reumatoidnog artritisa, mjerenog prema kriterijima odgovora American College of Rheumatology (ACR).
English: Do not use this medicine if you notice the solution is not clear or contains particles.
Croatian: Nemojte primijeniti otopinu ako primijetite da nije bistra ili da sadrži čestice.
English: If LIFMIOR has no effect on the child's condition after 12 weeks, your doctor may tell you to stop using this medicine.
Croatian: Ako LIFMIOR ne utječe na stanje djeteta nakon 12 tjedana terapije, Vaš će Vam liječnik možda reći da prestanete primjenjivati ovaj lijek.
English: During the withdrawal period, symptoms of psoriasis gradually returned with a median time to disease relapse of 3 months.
Croatian: U razdoblju obustavljanja lijeka simptomi psorijaze postupno su se vratili s medijanom vremena do relapsa bolesti od 3 mjeseca.
English: The pen can only be activated when the needle shield is completely pushed inside the pen.
Croatian: Brizgalica se može aktivirati samo kada je štitnik igle potpuno potisnut u brizgalicu.
English: It is very important that you tell your doctor if the child has ever had tuberculosis, or has been in close contact with someone who has had tuberculosis.
Croatian: Vrlo je važno da napomenete Vašem liječniku ako je dijete ikada imalo tuberkulozu ili je bilo u bliskom dodiru s osobom koja je imala tuberkulozu.
English: Stevens-Johnson syndrome, cutaneous vasculitis (including hypersensitivity vasculitis), erythema multiforme, lichenoid reactions
Croatian: StevensJohnsonov sindrom, kožni vaskulitis (uključujući hipersenzitivni vaskulitis), erythema multiforme, lihenoidne reakcije
English: Whilst pushing the pen firmly against the skin to ensure that the needle safety shield is fully depressed inside the pen, press the centre of the green button on top of the pen with your thumb to start the injection (see Diagram 5).
Croatian: Dok čvrsto potiskujete brizgalicu na kožu tako da je sigurnosni štitnik za iglu potpuno potisnut u unutrašnjost brizgalice, palcem pritisnite sredinu zelenog gumba na vrhu brizgalice kako bi započelo ubrizgavanje (vidjeti sliku 5).
English: Neoplasms benign, malignant and unspecified (including cysts and polyps)
Croatian: Dobroćudne, zloćudne i nespecificirane novotvorine (uključujući ciste i polipe)
English: This may include a thorough medical history, a chest X-ray and a tuberculin test.
Croatian: To može uključivati uzimanje temeljite anamneze, rendgensko snimanje srca i pluća te tuberkulinski test.
English: • Remove the plastic cap from the LIFMIOR vial (see Diagram 1).
Croatian: • Uklonite plastični poklopac s bočice LIFMIORa (vidjeti sliku 1).
English: They should not be used after the month and year shown.
Croatian: Ne smijete ih koristiti nakon isteka navedenog mjeseca i godine.
English: In clinical studies, concurrent administration of abatacept and LIFMIOR resulted in increased incidences of serious adverse events.
Croatian: U kliničkim ispitivanjima istodobna primjena abatacepta i LIFMIORa rezultirala je povećanom incidencijom ozbiljnih štetnih događaja.
English: 4 years.
Croatian: 4 godine.
English: Inject the solution after it has reached room temperature (15 to 30 minutes after taking the product from the refrigerator).
Croatian: Ubrizgajte otopinu nakon što je postigla sobnu temperaturu (15 do 30 minuta nakon što je lijek izvađen iz hladnjaka).
English: After you have withdrawn the LIFMIOR from the vial, you may have some air in the syringe.
Croatian: Nakon što se izvukli LIFMIOR iz bočice, u štrcaljki može preostati nešto zraka.
English: Treatment with LIFMIOR 25 mg resulted in substantial improvement at 12 months, with about 44% of patients achieving a normal HAQ score (less than 0.5).
Croatian: Liječenje dozom LIFMIORa od 25 mg rezultiralo je znatnim poboljšanjem nakon 12 mjeseci s oko 44% bolesnika koji su dostigli normalnu ocjenu na upitniku HAQ (manje od 0,5).
English: Serum concentration profiles were similar to those seen in adult rheumatoid arthritis patients.
Croatian: Profili serumskih koncentracija bili su slični onima zabilježenim u odraslih bolesnika s reumatoidnim artritisom.
English: For storage conditions of the reconstituted medicinal product, see section 6.3.
Croatian: Uvjete čuvanja rekonstituiranog lijeka vidjeti u dijelu 6.3.
English: There have also been rare (< 0.1%) reports of new onset CHF, including CHF in patients without known pre-existing cardiovascular disease.
Croatian: Također su rijetko (<0,1%) prijavljeni slučajevi novog nastupa kongestivnog zatajenja srca, uključujući kongestivno zatajenje srca u bolesnika s poznatom postojećom kardiovaskularnom bolešću.
English: Warning and precautions
Croatian: Upozorenja i mjere opreza
English: In patients who develop HBV infection, LIFMIOR should be stopped and effective anti-viral therapy with appropriate supportive treatment should be initiated.
Croatian: U bolesnika koji razviju HBV infekciju, terapiju LIFMIORom treba prekinuti i započeti učinkovitu antivirusnu terapiju s odgovarajućim suportivnim liječenjem.
English: • Tuberculosis: As cases of tuberculosis have been reported in patients treated with LIFMIOR, your doctor will check for signs and symptoms of tuberculosis before starting LIFMIOR.
Croatian: • Tuberkuloza: budući da su u bolesnika koju su liječeni LIFMIORom opisani slučajevi tuberkuloze, liječnik će provjeriti postoje li znakovi ili simptomi tuberkuloze prije nego što počnete terapiju LIFMIORom.
English: In a pooled data set of clinical trials, the overall incidence of opportunistic infections was 0.09% for the 15,402 subjects who received LIFMIOR.
Croatian: U skupnim podacima prikupljenim iz kliničkih ispitivanja ukupna incidencija oportunističkih infekcija bila je 0,09% na 15 402 ispitanika koji su dobivali LIFMIOR.
English: LIFMIOR is also indicated in the treatment of severe, active and progressive rheumatoid arthritis in adults not previously treated with methotrexate.
Croatian: LIFMIOR je također indiciran u liječenju teškog, aktivnog i progresivnog reumatoidnog artritisa u odraslih koji prethodno nisu bili liječeni metotreksatom.
English: The most commonly reported invasive fungal infections included Candida, Pneumocystis, Aspergillus, and Histoplasma.
Croatian: Najčešće prijavljene invazivne gljivične infekcije uključivale su Candidu, Pneumocystis, Aspergillus i Histoplasmu.
English: Each vial of LIFMIOR 10 mg should be used on a single occasion in a single patient, and the remainder of the vial should be discarded.
Croatian: Svaku bočicu LIFMIORa od 10 mg treba uporabiti jednokratno u samo jednog bolesnika, a ostatak sadržaja bočice treba baciti.
English: • While holding the needle and container in one hand, pick up the syringe and insert the syringe tip into the needle opening.
Croatian: • Držeći iglu i spremnik u jednoj ruci, uzmite štrcaljku i uvedite vrh štrcaljke u otvor igle.
English: • if you or the child have, or are at risk of developing a serious blood infection called sepsis.
Croatian: • ako Vi ili dijete imate ili postoji opasnost od razvoja ozbiljne infekcije krvi zvane sepsa.
English: In each of the JIA subtypes, the majority of patients met ACR Pedi 30 criteria and demonstrated clinical improvement in secondary endpoints such as number of tender joints and physician global assessment.
Croatian: U svakom od podtipova JIA u većine bolesnika bili su zadovoljeni ACR Pedi 30 kriteriji i pokazalo se kliničko poboljšanje u sekundarnim mjerama ishoda kao što su broj bolnih zglobova i opća procjena liječnika.
English: Hypoglycaemia in patients treated for diabetes
Croatian: Hipoglikemija u bolesnika liječenih zbog šećerne bolesti
English: Although not conclusive, data from one of these trials suggest a possible tendency toward worsening CHF in those patients assigned to LIFMIOR treatment.
Croatian: Iako ne uvjerljivo, podaci iz jednog od ovih ispitivanja upućivali su na moguću tendenciju pogoršanja kongestivnog zatajenja srca u bolesnika liječenih LIFMIORom.
English: Study 2 also had a drug withdrawal period during which patients who achieved a PASI improvement of at least 50% at week 24 had treatment stopped.
Croatian: U ispitivanju 2 također je postojao period bez primjene lijeka za vrijeme kojeg je, u bolesnika s postignutim PASI poboljšanjem od najmanje 50% u 24. tjednu, primjena lijeka obustavljena.
English: In long-term (up to 34 months) open-label studies where LIFMIOR was given without interruption, clinical responses were sustained and safety was comparable to shorter-term studies.
Croatian: U dugotrajnim (do 34 mjeseca) otvorenim ispitivanjima gdje se LIFMIOR primjenjivao bez prekida klinički odgovor bio je kontinuiran i sigurnost primjene bila je usporediva s ispitivanjima kraćeg trajanja.
English: Women using LIFMIOR should not breast-feed, since LIFMIOR passes into human breast milk.
Croatian: Žene koje primaju LIFMIOR ne bi smjele dojiti, budući da LIFMIOR prelazi u majčino mlijeko.
English: Serious allergic/anaphylactic reactions (including angioedema, bronchospasm), sarcoidosis
Croatian: Ozbiljne alergijske/anafila ktične reakcije (uključujući angioedem, bronhospazam), sarkoidoza
English: If any of the following happen to the child, do not give the child more LIFMIOR.
Croatian: Ako se kod djeteta pojavi bilo što od sljedećeg, prestanite djetetu davati LIFMIOR.
English: • if you or the child have an infection of any kind.
Croatian: • ako Vi ili dijete imate bilo kakvu infekciju.
English: Interstitial lung disease (including pneumonitis and pulmonary fibrosis)*
Croatian: Intersticijska plućna bolest (uključujući pneumonitis i plućnu fibrozu)*
English: Method of administration LIFMIOR is administered by subcutaneous injection (see section 6.6).
Croatian: Način primjene LIFMIOR se primjenjuje supkutanom injekcijom (vidjeti dio 6.6).
English: If you notice any of the following, you or the child may need urgent medical attention.
Croatian: Ako primijetite bilo koji od sljedećih znakova, možda će te Vi ili dijete trebati hitnu medicinsku pomoć.
English: These include rare reports of pancytopenia and very rare reports of aplastic anaemia.
Croatian: One uključuju rijetke prijave pancitopenije i vrlo rijetke prijave aplastične anemije.
English: The incidence of non-cutaneous malignancies of various types was significantly higher in patients treated with LIFMIOR than in the control group.
Croatian: Incidencija različitih vrsta ne-kožnih zloćudnih bolesti bila je značajno veća u bolesnika koji su liječeni LIFMIORom u odnosu na kontrolnu skupinu.
English: After preparing the LIFMIOR solution, immediate use is recommended.
Croatian: Nakon pripreme otopine LIFMIORa, preporučuje se odmah je primijeniti.
English: Wegener's granulomatosis
Croatian: Wegenerova granulomatoza
English: During the first 12 weeks of the double-blind treatment period, patients received placebo or one of the above three LIFMIOR doses.
Croatian: Tijekom prvih 12 tjedana dvostruko slijepog perioda bolesnici su primali placebo ili jednu od tri navedene doze LIFMIORa.
English: LIFMIOR did not induce lethality or notable signs of toxicity in mice or rats following a single subcutaneous dose of 2000 mg/kg or a single intravenous dose of 1000 mg/kg.
Croatian: LIFMIOR nije uzrokovao smrtnost ni vidljive znakove toksičnosti u miševa i štakora nakon jednokratne supkutane doze od 2000 mg/kg, ni nakon jednokratne intravenske doze od 1000 mg/kg.
English: Each injection should be given at least 3 cm from where you last injected.
Croatian: Svaku injekciju treba dati najmanje 3 cm dalje od prethodnog mjesta uboda.
English: Psoriatic Arthritis Response n = 104
Croatian: Odgovori bolesnika sa psorijatičnim artritisom n = 104
English: Some white foam may remain in the vial - this is normal.
Croatian: Moguće je da u bočici ostane nešto bijele pjene - to je normalno.
English: If you are not sure, please talk to your doctor.
Croatian: Ako niste sigurni obratite se svom liječniku.
English: There have been reports of worsening of hepatitis C in patients receiving LIFMIOR.
Croatian: Opisani su slučajevi pogoršanja hepatitisa C u bolesnika koji su primali LIFMIOR.
English: If the child in your care has Wegener's granulomatosis, talk to your doctor.
Croatian: Ako dijete o kojem skrbite ima Wegenerovu granulomatozu, razgovarajte sa svojim liječnikom.
English: Treatment with LIFMIOR may result in reactivation of hepatitis B in patients who have previously been infected with the hepatitis B virus.
Croatian: Liječenje LIFMIORom može reaktivirati hepatitis B u bolesnika koji su prethodno bili zaraženi virusom hepatitisa B.
English: Fold the paper cover back over the tray and place the carton containing any remaining pre-filled syringes back into the refrigerator.
Croatian: Papirnati pokrov vratite natrag preko posude i vratite kutiju s preostalim napunjenim štrcaljkama u hladnjak.
English: No clinically significant pharmacokinetic drug-drug interactions were observed in studies with methotrexate, digoxin or warfarin.
Croatian: Nisu opažene klinički značajne farmakokinetičke interakcije između lijekova u ispitivanjima s metotreksatom, digoksinom ili varfarinom.
English: Do NOT touch this area again before giving the injection.
Croatian: Ne dirajte to područje ponovo prije davanja injekcije.
English: Do not use the solution if it is discoloured, cloudy, or if particles other than those described above are present.
Croatian: Nemojte koristiti otopinu ako je obojana, zamućena ili sadržava čestice drugačije od opisanih.
English: At week 104, 8 subjects had progressed to a score of bilateral Grade 2 on spinal X-ray according to the modified New York Radiological Grade, indicative of axial spondyloarthropathy.
Croatian: U 104. tjednu 8 je ispitanika napredovalo do 2. stupnja bilateralno, mjereno rendgenom kralježnice prema modificiranim New York kriterijima za radiološku ocjenu, što ukazuje na aksijalnu spondiloartropatiju.
English: LIFMIOR is a medicine that is made from two human proteins.
Croatian: LIFMIOR je lijek napravljen od dvije ljudske bjelančevine.
English: Step 2: Choosing an injection site (see Diagram 2)
Croatian: Korak 2: Odabir mjesta za injekciju (vidjeti sliku 2)
English: The impact of long-term treatment with LIFMIOR on the development of autoimmune diseases is unknown.
Croatian: Nije poznat utjecaj dugotrajnog liječenja LIFMIORom na razvoj autoimunih bolesti.
English: The results are shown in the figure below.
Croatian: Rezultati su prikazani na slici niže.
English: Remove only the portion of liquid as directed by your child's doctor.
Croatian: Izvucite samo dio sadržaja bočice kako je odredio liječnik Vašeg djeteta.
English: Inspect the solution in the pen by looking through the clear inspection window.
Croatian: Pregledajte otopinu u brizgalici tako što ćete je pogledati kroz prozirni prozorčić za provjeru.
English: Study 3 evaluated 583 patients and had the same inclusion criteria as study 2.
Croatian: Ispitivanje 3 procijenilo je 583 bolesnika i imalo je iste kriterije uključivanja kao i ispitivanje
English: • This medicine has been prescribed for a child in your care.
Croatian: • Ovaj je lijek propisan djetetu za koje skrbite.
English: LIFMIOR + Methotrexate (n = 231)
Croatian: LIFMIOR + metotreksat (n = 231)
English: Based on current knowledge, a possible risk for the development of lymphomas, leukaemia or other haematopoietic or solid malignancies in patients treated with a TNF-antagonist cannot be excluded.
Croatian: Prema postojećem znanju ne može se isključiti mogući rizik od razvoja limfoma, leukemija ili drugih hematopoetskih zloćudnih bolesti ili solidnih tumora u bolesnika liječenih antagonistima TNF-a.
English: After waiting approximately 15-30 minutes for the solution in the pen to warm to room temperature, wash your hands with soap and water.
Croatian: Nakon što ste pričekali približno 15-30 minuta da otopina u brizgalici postigne sobnu temperaturu, operite ruke sapunom i vodom.
English: Etanercept crosses the placenta and has been detected in the serum of infants born to female patients treated with LIFMIOR during pregnancy.
Croatian: Etanercept prolazi kroz placentu i može se otkriti u serumu dojenčadi žena koje su bile liječene LIFMIORom tijekom trudnoće.
English: However, any of the above symptoms may indicate an allergic reaction to LIFMIOR, so you should seek immediate medical attention.
Croatian: Međutim, bilo koji od gore navedenih simptoma može upućivati na alergijsku reakciju na LIFMIOR, stoga je potrebno odmah zatražiti pomoć liječnika.
English: If any serious allergic or anaphylactic reaction occurs, LIFMIOR therapy should be discontinued immediately and appropriate therapy initiated.
Croatian: U slučaju pojave bilo kakve ozbiljne alergijske ili anafilaktičke reakcije mora se odmah obustaviti terapija LIFMIORom i započeti odgovarajuća terapija.
English: Reactivation of hepatitis B in patients who were previously infected with the hepatitis B virus (HBV) and had received concomitant TNF-antagonists, including LIFMIOR, has been reported.
Croatian: Zabilježena je reaktivacija hepatitisa B u bolesnika koji su prethodno bili zaraženi virusom hepatitisa B (HBV) i primali antagoniste TNF-a, uključujući LIFMIOR.
English: Allergic reactions have included angioedema and urticaria; serious reactions have occurred.
Croatian: Zabilježene alergijske reakcije uključivale su angioedem i urtikariju; zabilježene su i ozbiljne reakcije.
English: You have been prescribed a 50 mg strength of LIFMIOR.
Croatian: Propisana Vam je jačina od 50 mg LIFMIORa.
English: Adult population
Croatian: Odrasla populacija
English: Your doctor may decide to continue to monitor you or the child for the presence of infections after you or the child stop using LIFMIOR.
Croatian: Vaš liječnik može odlučiti da Vas ili dijete nastavi pratiti s obzirom na prisutnost infekcije nakon što ste Vi ili dijete prestali uzimati LIFMIOR.
English: Two juvenile idiopathic arthritis patients developed varicella infection and signs and symptoms of aseptic meningitis, which resolved without sequelae.
Croatian: Dva bolesnika s juvenilnim idiopatskim artritisom razvila su infekciju varicella virusom te znakove i simptome aseptičkog meningitisa koji su se povukli bez trajnih posljedica.
English: Evidence of efficacy for the once weekly dosing regimen in this patient population has been based on data from the study in patients with ankylosing spondylitis.
Croatian: Dokaz djelotvornosti za režim doziranja jednom tjedno u ovoj populaciji bolesnika temeljen je na podacima iz ispitivanja u bolesnika s ankilozantnim spondilitisom.
English: Preclinical data about peri- and postnatal toxicity of etanercept and of effects of etanercept on fertility and general reproductive performance are not available.
Croatian: Neklinički podaci o perinatalnoj i postnatalnoj toksičnosti etanercepta i njegovom učinku na plodnost i opću sposobnost reprodukcije nisu dostupni.
English: In controlled trials in patients with plaque psoriasis, approximately 13.6% of patients treated with LIFMIOR developed injection site reactions compared with 3.4% of placebo-treated patients during the first 12 weeks of treatment.
Croatian: U kontroliranim ispitivanjima u bolesnika s plak psorijazom otprilike 13,6% bolesnika liječenih LIFMIORom razvilo je reakciju na mjestu primjene injekcije u usporedbi s 3,4% placebom liječenih bolesnika za vrijeme prvih 12 tjedana liječenja.
English: The majority of the reports with a fatal outcome were in patients with Pneumocystis pneumonia, unspecified systemic fungal infections, and aspergillosis (see section 4.4).
Croatian: Većina prijava sa smrtnim ishodom zabilježena je u bolesnika s pneumocističnom pneumonijom, nespecifičnim sistemskim gljivičnim infekcijama i aspergilozom (vidjeti dio 4.4).
English: It is very important that you tell your doctor if you or the child have ever had tuberculosis, or have been in close contact with someone who has had tuberculosis.
Croatian: Vrlo je važno da napomenete Vašem liječniku ako ste Vi ili dijete ikada imali tuberkulozu ili ste bili u bliskom dodiru s osobom koja je imala tuberkulozu.
English: Withdrawing the LIFMIOR solution from the vial f.
Croatian: Izvlačenje otopine LIFMIORa iz bočice f.
English: In clinical trials, no interactions have been observed when LIFMIOR was administered with glucocorticoids, salicylates (except sulfasalazine), nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, or methotrexate.
Croatian: U kliničkim ispitivanjima nisu primijećene interakcije prilikom primjene LIFMIORa s glukokortikoidima, salicilatima (osim sulfasalazina), nesteroidnim protuupalnim lijekovima (NSAIL), analgeticima ili metotreksatom.
English: If this occurs, you should stop using LIFMIOR.
Croatian: Ako se to dogodi, morate prestati uzimati LIFMIOR.
English: Treatment with LIFMIOR should not be initiated in patients with active infections, including chronic or localised infections.
Croatian: Liječenje LIFMIORom se ne smije započeti u bolesnika s aktivnim infekcijama, uključivši kronične i lokalizirane infekcije.
English: Clinical responses were expressed as percentages of patients achieving the ACR 20, 50, and 70 response and percentages with improvement in Psoriatic Arthritis Response Criteria (PsARC).
Croatian: Klinički odgovori su prikazani kao postotak bolesnika koji su dostigli odgovore ACR 20, 50 i 70 te kao postotak bolesnika s poboljšanjem u PsARC (Psoriatic Arthritis Response Criteria).
English: • Signs of autoimmune reactions (where antibodies are made that may harm normal tissues in the body) such as pain, itching, weakness, and abnormal breathing, thinking, sensation, or vision
Croatian: • Znakovi autoimune reakcije (kada se stvaraju protutijela koja mogu oštetiti normalno tkivo u tijelu), kao što su bol, svrbež, slabost i poremećeno disanje, razmišljanje, osjet ili vid
English: • Psoriatic arthritis in patients from the age of 12 years
Croatian: • Psorijatični artritis u bolesnika od navršenih 12 godina života.