FrancophonIA/ELRC3.0 huggingface dataset:
English: The treatment with a thiazide may influence the glucose tolerance.
Slovenian: Zdravljenje s tiazidi lahko poslabša toleranco za glukozo.
English: Dose titration with the individual components (losartan and hydrochlorothiazide) is recommended.
Slovenian: Priporočamo titriranje odmerkov s posameznima učinkovinama (losartanom in hidroklorotiazidom).
English: Losartan and hydrochlorothiazide is not for use as initial therapy, but in patients whose blood pressure is not adequately controlled by losartan potassium or hydrochlorothiazide alone.
Slovenian: Kombinacija losartana in hidroklorotiazida ni namenjena za začetno zdravljenje, ampak bolnikom, pri katerih krvni tlak samo z losartanom ali samo s hidroklorotiazidom ni ustrezno nadzorovan.
English: Common: Hyperkalaemia, mild reduction of haematocrit and haemoglobin Uncommon: Mild increase in urea and creatinine serum levels Very rare: Increase in hepatic enzymes and bilirubin.
Slovenian: Preiskave pogoste: hiperkaliemija, blago znižan hematokrit in hemoglobin občasne: blago zvišanje sečnine v serumu in kreatinina v serumu zelo redke: zvišanje jetrnih encimov in bilirubina
English: The usual maintenance dose of Cozaar Comp is one tablet of Cozaar Comp 50 mg/12.5 mg (losartan 50 mg/HCTZ 12.5 mg) once daily.
Slovenian: Običajni vzdrževalni odmerek zdravila Cozaar Comp je ena tableta Cozaar Comp 50 mg/12,5 mg (losartan 50 mg/HCTZ 12,5 mg) enkrat na dan.
English: In nondiabetic hypertensive patients with proteinuria, the administration of losartan potassium significantly reduces proteinuria, fractional excretion of albumin and IgG.
Slovenian: Pri hipertonikih, ki nimajo sladkorne bolezni, imajo pa proteinurijo, dajanje losartana pomembno zmanjša proteinurijo, frakcijsko izločanje albumina in IgG.
English: • Class Ia antiarrythmics (eg quinidine, hydroquinidine, disopyramide).
Slovenian: • antiaritmiki razreda Ia (npr. kinidin, hidrokinidin, disopiramid)
English: If goal blood pressure (<140/90 mmHg) was not reached, hydrochlorothiazide (12.5 mg) was added first and, if needed, the dose of losartan or atenolol was then increased to 100 mg once daily.
Slovenian: Če ciljnega krvnega tlaka (< 140/90 mmHg) niso dosegli, so najprej dodali hidroklorotiazid (12,5 mg), potem pa so, če je bilo potrebno, povečali odmerek losartana ali atenolola na 100 mg enkrat na dan. Za doseg ciljnega krvnega tlaka so, če je bilo potrebno, dodali še druge antihipertenzive, razen zaviralcev ACE, antagonistov angiotenzina II ali beta zaviralcev.
English: During the administration of losartan the removal of the angiotensin II negative feedback on renin secretion leads to increased plasma-renin activity (PRA).
Slovenian: Med dajanjem losartana odsotnost negativne povratne zveze angiotenzina II na izločanje renina povzroči povečano aktivnost renina v plazmi.
English: Exacerbation or activation of systemic lupus erythematosus has been reported with the use of thiazides.
Slovenian: Pri uporabi tiazidov so poročali tudi o poslabšanju ali aktivaciji sistemskega eritematoznega lupusa.
English: If you become pregnant while on Cozaar Comp, tell your doctor immediately.
Slovenian: Če jemljete zdravilo Cozaar Comp in zanosite, se takoj posvetujte z zdravnikom.
English: Electrolyte imbalances are common in patients with renal impairment, with or without diabetes, and should be addressed.
Slovenian: Pri bolnikih z okvaro ledvic, s sladkorno boleznijo ali brez nje, so pogosta elektrolitska neravnovesja, ki jih je potrebno urediti.
English: The active substances are losartan potassium and hydrochlorothiazide.
Slovenian: Zdravilni učinkovini sta kalijev losartanat in hidroklorotiazid.
English: Belgium Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B-1180 Brussels
Slovenian: Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B1180 Bruselj
English: the CHMP has recommended the amendment of the Marketing Authorisation(s) for which the Summary of Product Characteristics, labelling and package leaflet are set out in Annex III for Cozaar Comp. and associated names (see Annex I).
Slovenian: je CHMP za zdravilo Cozaar Comp. in z njim povezana imena (glejte Dodatek I) priporočil spremembo dovoljenj za promet z zdravilom, katerih povzetek glavnih značilnosti zdravila, označevanje in navodila za uporabo so opredeljeni v Dodatku III.
English: As with any antihypertensive agents, excessive blood pressure decrease in patients with ischaemic cardiovascular and cerebrovascular disease could result in a myocardial infarction or stroke.
Slovenian: Koronarna srčna bolezen in možganskožilna bolezen Tako kot pri drugih antihipertenzivih lahko preveliko znižanje krvnega tlaka pri bolnikih z ishemično srčnožilno in možganskožilno boleznijo povzroči miokardni infarkt ali možgansko kap.
English: Neither losartan nor the active metabolite can be removed by hemodialysis.
Slovenian: S hemodializo ne moremo odstraniti niti losartana niti njegovega aktivnega presnovka.
English: Musculoskeletal and connective tissue disorders Common: Muscle cramp, back pain, leg pain, myalgia Uncommon: Arm pain, joint swelling, knee pain, musculoskeletal pain, shoulder pain, stiffness, arthralgia, arthritis, coxalgia, fibromyalgia, muscle weakness
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva pogoste: mišični krči, bolečina v hrbtu, bolečina v nogi, mialgija občasne: boleča roka, otekel sklep, boleče koleno, mišično-skeletne bolečine, bolečine v rami, okornost, artralgija, artritis, bolečina v kolku, fibromialgija, šibkost mišic
English: Periodic monitoring of serum potassium and ECG is recommended when Losartan/hydrochlorothiazide is administered with medicinal products affected by serum potassium disturbances (e.g. digitalis glycosides and antiarrhythmics) and with the following torsades de pointes
Slovenian: Zdravila, na katera vplivajo spremenjene vrednosti kalija v serumu Periodično spremljanje vrednosti kalija v serumu in EKG priporočamo, kadar se losartan/hidroklorotiazid uporablja z zdravili, na katera vplivajo spremembe količine kalija v serumu (npr. glikozidi digitalisa in antiaritmiki), in z naslednjimi zdravili, ki povzročajo torsades de pointes ventrikularno tahikardijo (vključno z nekaterimi antiaritmiki), katere glavni povzročitelj je hipokaliemija:
English: Merck Sharp & Dohme Ltd., Hertfordshire Road, Hoddesdon, Hertfordshire, EN11 9BU, United Kingdom
Slovenian: Merck Sharp & Dohme Ltd., Hertfordshire Road, Hoddesdon, Hertfordshire, EN11 9BU, Velika Britanija
English: Use in patients with intravascular volume depletion Volume and /or sodium depletion should be corrected prior to administration of Losartan/HCTZ tablets.
Slovenian: Uporaba pri bolnikih z zmanjšanim intravaskularnim volumnom Pred uporabo tablet losartan/HCTZ je treba pozdraviti zmanjšanje intravaskularnega volumna in/ali količine natrija.
English: Patients should be rehydrated before the administration.
Slovenian: Bolnike je treba pred uporabo jodovega kontrastnega sredstva rehidrirati.
English: The diuretic action of HCTZ reduces plasma volume, with consequent increase in plasma renin activity, increase in adolsterone secretion, increase in urinary K+ and HCO-3 loss, and decrease in plasma K+.
Slovenian: Diuretični učinek HCTZ zmanjša prostornino plazme, kar posledično poveča aktivnost plazemskega renina, sekrecijo aldosterona, izgubo K+ in HCO-3 v urinu ter zmanjša koncentracijo K+ v plazmi.
English: The use of Cozaar Comp is contra-indicated during the 2nd and 3rd trimester of pregnancy (see section 4.3 and 4.4).
Slovenian: Uporaba zdravila Cozaar je kontraindicirana v 2. in 3. trimesečju nosečnosti (glejte poglavji 4.3 in
English: • Hives, itching, inflammation of the skin, rash, redness of the skin, sensitivity to light, dry skin, flushing, sweating, hair loss,
Slovenian: • koprivnica, srbenje, vnetje na koži, izpuščaj, rdečina na koži, občutljivost na svetlobo, suha koža, zardevanje, potenje, izpadanje las
English: Uncommon: Agranulocytosis, aplastic anaemia, haemolytic anaemia, leukopenia, purpura, thrombocytopenia
Slovenian: Občasne: agranulocitoza, aplastična anemija, hemolitična anemija, levkopenija, purpura, trombocitopenija
English: Always take Cozaar Comp exactly as your doctor has instructed you.
Slovenian: Zdravilo Cozaar Comp poskusite jemati tako, kot vam je predpisal zdravnik.
English: The renin-aldosterone link is mediated by angiotensin II and therefore coadministration of an angiotensin II receptor antagonist tends to reverse the potassium loss associated with thiazide diuretics.
Slovenian: Zanko renin-aldosteron uravnava angiotenzin II, zato sočasna uporaba antagonista receptorjev angiotenzina II zaustavi izgubo kalija, povezano s tiazidnimi diuretiki.
English: • Weakness, tiredness, chest pain,
Slovenian: • slabotnost, urujenost, bolečina v prsnem košu
English: • Muscle pain or cramps, leg pain, back pain,
Slovenian: • bolečine v mišicah, mišični krči, bolečine v nogah, bolečine v hrbtu
English: The diuretic action of hydrochlorothiazide reduces plasma volume, increases plasma renin activity and increases aldosterone secretion, with consequent increases in urinary potassium and bicarbonate loss, and decreases in serum potassium.
Slovenian: Z diuretičnim učinkom hidroklorotiazid zmanjša volumen plazme, poveča reninsko aktivnost v plazmi ter poveča izločanje aldosterona, s posledičnim povečanjem kalija v urinu in zmanjšanjem bikarbonata, in zmanjša količino kalija v serumu.
English: Film coated tablets
Slovenian: Filmsko obložene tablete.
English: Angiooedema
Slovenian: Angioedem
English: • Insomnia, headache, dizziness,
Slovenian: • nespečnost, glavobol, omotica
English: Luxembourg Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B-1180 Brussels, Belgium
Slovenian: Luksemburg Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B1180 Bruselj, Belgija
English: Iodine Contrast Media
Slovenian: Jodirano kontrastno sredstvo
English: Merck Sharp & Dohme Limited Hertford Road, Hoddesdon, Herts EN11 9BU, United Kingdom
Slovenian: Velika Britanija Merck Sharp & Dohme Limited Hertford Road, Hoddesdon, Herts EN11 9BU, Velika Britanija
English: As with other drugs that affect the renin-angiotensin-aldosterone system, increases in blood urea and serum creatinine have also been reported in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney; these changes in renal function may be reversible upon discontinuation of therapy.
Slovenian: Tako kot pri drugih zdravilih, ki vplivajo na sistem renin-angiotenzin-aldosteron, so pri bolnikih z obojestranskim zožanjem ledvične arterije ali zožanjem arterije ene same delujoče ledvice poročali o zvišanju sečnine v krvi in zvišanju kreatinina v serumu.
English: Losartan and hydrochlorothiazide tablets are not recommended for haemodialysis patients.
Slovenian: Kombinacije losartan/HCTZ ne priporočamo bolnikom na hemodializi.
English: Cozaar Comp 100 mg/12.5 mg also contain: white color concentrate [or the individual ingredients of the concentrate: hydroxypropyl cellulose (E463), hypromellose (E464) and titanium dioxide (E171)] and carnauba wax (E903).
Slovenian: Cozaar Comp 100 mg/12,5 mg vsebuje tudi: koncentrat bele barve [ali posamezne sestavine koncentrata: hidroksipropilcelulozo (E463), hipromelozo (E464) in titanov dioksid (E171)] in karnauba vosek (E903).
English: The CHMP considered that the following warnings should be included in the SPC in all MSs: Haemodialysis; Black patients; Obstructive valvular disease; Surgery/anaesthesia.
Slovenian: Poglavje 4.4 Posebna opozorila in previdnostni ukrepi CHMP je menil, da je treba v vseh različicah povzetka glavnih značilnosti zdravila vključiti naslednja opozorila: hemodializa; črni bolniki; obstruktivna bolezen srčnih zaklopk; kirurški poseg/anestezija.
English: Hydrochlorothiazide crosses the placental but not the blood-brain barrier and is excreted in breast milk.
Slovenian: Hidroklorotiazid prehaja placento, vendar ne prehaja krvno-možganske bariere.
English: Dosage adjustment of uricosuric medicinal products may be necessary since hydrochlorothiazide may raise the level of serum uric acid.
Slovenian: Zdravila za zdravljenje protina (probenecid, sulfinpirazon in alopurinol) Morda je treba prilagoditi odmerjanje urikozuričnih zdravil, ker hidroklorotiazid lahko poveča količino sečne kisline v serumu.
English: Angiotensin II binds to the AT1 receptor found in many tissues (e.g. vascular smooth muscle, adrenal gland, kidneys and the heart)
Slovenian: Angiotenzin II se veže na AT1 receptorje, ki se nahajajo v številnih tkivih (npr. gladkih mišicah krvnih žil, nadledvični žlezi, ledvicah in srcu), in sproži več pomembnih bioloških učinkov, vključno z vazokonstrikcijo in sproščanjem aldosterona.
English: Because losartan decreases uric acid, losartan in combination with hydrochlorothiazide attenuates the diureticinduced hyperuricemia.
Slovenian: Losartan znižuje koncentracijo sečne kisline v krvi, zato v kombinaciji s hidroklorotiazidom ublaži hiperurikemijo, ki jo povzroči diuretik.
English: Merck Sharp & Dohme GmbH Donau-City-Straße 6
Slovenian: Merck Sharp & Dohme GmbH Donau-City-Straße 6, 1220 Dunaj Avstrija
English: • Constipation, wind, stomach upsets, stomach spasms, vomiting, dry mouth, inflammation of a salivary gland, toothache,
Slovenian: • zaprtje, vetrovi, razdražen želodec, krči želodca, bruhanje, suha usta, vnetje žleze slinavke, zobobol
English: What Cozaar Comp looks like and contents of the pack Cozaar Comp 50 mg/12.5 mg is supplied as scored or unscored film-coated tablets.
Slovenian: Izgled zdravila Cozaar Comp in vsebina pakiranja Cozaar Comp 50 mg/12,5 mg je na voljo v obliki filmsko obloženih tablet z ali brez razdelilne zareze.
English: Dilutional hyponatraemia may occur in oedematous patients in hot weather.
Slovenian: V vročem vremenu se pri bolnikih z edemi lahko pojavi dilucijska hiponatriemija.
English: Cozaar Comp 50 mg/12.5 mg Each tablet contains 63.13 mg lactose monohydrate.
Slovenian: Cozaar Comp 50 mg/12,5 mg Vsaka tableta vsebuje 63,13 mg laktoze monohidrata.
English: Store Cozaar Comp in the original package.
Slovenian: Zdravilo Cozaar Comp shranjujte v originalni ovojnini.
English: • Cough, upper airway infection, congestion in the nose, sinusitis, sinus disorder,
Slovenian: • kašelj, okužba zgornjih dihal, zamašen nos, vnetje sinusov, težave s sinusi
English: Uncommon: Hypotension, orthostatic hypotension, sternalgia, angina pectoris, grade II-AV block, cerebrovascular event, myocardial infarction, palpitation, arrhythmias (atrial fibrillations, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation)
Slovenian: stopnje, cerebrovaskularni dogodek, miokardni infarkt, palpitacije, aritmije (atrijska fibrilacija, sinusna bradikardija, tahikardija, ventrikularna tahikardija,fibrilacija ventriklov)
English: Sweden Merck Sharp & Dohme PO Box 581
Slovenian: Nizozemska Merck Sharp & Dohme PO Box 581
English: PHARMACEUTICAL FORM AND CONTENTS 4, 7, 10, 14, 20, 28, 30, 50, 56, 84, 98, or 280 film-coated tablets.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 4, 7, 10, 14, 20, 28, 30, 50, 56, 84, 98 ali 280 filmsko obloženih tablet.
English: Pregnancy and Lactation should be contraindicated and the appropriate wording included in sections 4.3, 4.4 and 4.6 of the SPC, and the relevant sections of the Package Leaflet.
Slovenian: Nosečnost in dojenje je treba kontraindicirati, v poglavja 4.3, 4.4 in 4.6 povzetka glavnih značilnosti zdravila ter ustrezna poglavja navodil za uporabo pa vnesti primerno besedilo.
English: Coadministration of a thiazide may increase the incidence of hypersensitivity reactions to allopurinol.
Slovenian: Sočasna uporaba tiazida lahko poveča pojavnost preobčutljivostnih reakcij na alopurinol.
English: The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study was a randomised, triple-blind, active-controlled study in 9193 hypertensive patients aged 55 to 80 years with ECGdocumented left ventricular hypertrophy.
Slovenian: Vključevala je 9.193 hipertenzivnih bolnikov, starih od 55 do 80 let, z EKG-jem potrjeno hipertrofijo levega prekata.
English: Vascular disorders Uncommon: Vasculitis
Slovenian: Žilne bolezni občasne: vaskulitis
English: - Pregnancy and Lactation should be contraindicated and the appropriate wording included in sections 4.3, 4.4 and 4.6 of the SPC, and the relevant sections of the Package Leaflet.
Slovenian: - je treba nosečnost in dojenje kontraindicirati, v poglavja 4.3, 4.4 in 4.6 povzetka glavnih značilnosti zdravila ter ustrezna poglavja navodil za uporabo pa vnesti primerno besedilo;
English: Hepato-biliary disorders Rare: Hepatitis
Slovenian: Bolezni jeter, žolčnika in žolčevodov Redke: hepatits
English: Uncommon: Nervousness, paraesthesia, peripheral neuropathy, tremor, migraine, syncope
Slovenian: Bolezni živčevja pogoste: glavobol, omotica občasne: nervoznost, parestezija, periferna nevropatija, tremor, migrena, sinkopa
English: Uncommon: Anxiety, anxiety disorder, panic disorder, confusion, depression, abnormal dreams, sleep disorder, somnolence, memory impairment
Slovenian: Psihiatrične motnje pogoste: nespečnost občasne: anksioznost, anksiozne motnje, panične motnje, zmedenost, depresija, nenormalne sanje, motnje spanja, zaspanost, motnje spomina
English: Cozaar Comp 100 mg/25 mg Each tablet contains 126.26 mg lactose monohydrate.
Slovenian: Cozaar Comp 100 mg/25 mg Vsaka tableta vsebuje 126,26 mg laktoze monohidrata.
English: • Refractory hyponatraemia
Slovenian: • Refraktorna hiponatriemija.
English: When given concurrently, the following drugs may interact with thiazide diuretics:
Slovenian: Pri sočasni uporabi lahko na tiazidne diuretike vplivajo naslednja zdravila:
English: The maximum daily dose is 2 tablets per day of Losartan / Hydrochlorothiazide 50 mg/12.5 mg Film-Coated Tablets or 1 tablet daily of Losartan / Hydrochlorothiazide 100 mg/25 mg Film-Coated Tablets
Slovenian: Največji dnevni odmerek sta dve filmsko obloženi tableti losartan/hidroklorotiazid 50 mg/12,5 mg na dan ali ena filmsko obložena tableta losartan/hidroklorotiazid 100 mg/25 mg na dan.
English: Eye disorders Uncommon: Blurred vision, burning/stinging in the eye, conjunctivitis, decrease in visual acuity
Slovenian: Očesne bolezni občasne: zamegljen vid, pekoč občutek/občutek zbadanja v očesu, konjunktivitis, zmanjšana ostrina vida
English: • if you have had gout
Slovenian: • če imate protin.
English: Luxembourg Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Brussels, Belgium
Slovenian: Luksemburg Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Brussels, Belgium
English: Renal and urinary disorders Uncommon: Nocturia, urinary frequency, urinary tract infection
Slovenian: Bolezni sečil občasne: nokturija, pogosto uriniranje, okužba urinarnega trakta
English: PHARMACEUTICAL FORM AND CONTENTS 14, 15, 28, 30, 50, 56, 84, 90, 98, or 280 film coated-tablets.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 14, 15, 28, 30, 50, 56, 84, 90, 98 ali 280 filmsko obloženih tablet.
English: Cozaar Comp 100 mg/12.5 mg Each tablet contains 88.40 mg lactose monohydrate.
Slovenian: Cozaar Comp 100 mg/12,5 mg Vsaka tableta vsebuje 88,40 mg laktoze monohidrata.
English: • if you are diabetic
Slovenian: • če imate sladkorno bolezen.
English: Belgium Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Brussels, Belgium
Slovenian: Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Bruselj, Belgija
English: You must not take Cozaar Comp if you are breast-feeding.
Slovenian: Zdravila Cozaar Comp ne smete jemati, če dojite.
English: Please also inform your doctor when it is planned to apply iodine contrast media about taking Cozaar Comp.
Slovenian: Če boste imeli preiskavo z jodirnim kontrastnim sredstvom, zdravniku povejte, da jemljete zdravilo Cozaar Comp.
English: This can be increased to 2 tablets once daily of Losartan / Hydrochlorothiazide 50 mg/12.5 mg Film-Coated Tablets or changed to 1 tablet daily of Losartan / Hydrochlorothiazide 100 mg/25 mg Film-Coated Tablets (a stronger strength) per day.
Slovenian: Odmerek se lahko poveča na 2 filmsko obloženi tableti losartan/hidroklorotiazid 50 mg/12,5 mg enkrat na dan ali eno tableto losartan/hidroklorotiazid 100 mg/25 mg (večja jakost) na dan.
English: PHARMACEUTICAL FORM AND CONTENTS 7, 14, 28, 30, 50, 56, 84, 90, 98, or 280 film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 7, 14, 28, 30, 50, 56, 84, 90, 98 ali 280 filmsko obloženih tablet.
English: Metabolism and nutrition disorders Uncommon: Anorexia, gout
Slovenian: Presnovne in prehranske motnje občasne: anoreksija, protin
English: HOW TO TAKE COZAAR COMP
Slovenian: KAKO JEMATI ZDRAVILO COZAAR COMP
English: Cozaar Comp is contraindicated for patients with severe hepatic impairment (see section 4.3 and
Slovenian: Zdravilo Cozaar Comp je kontraindicirano pri bolnikih s hudo okvaro jeter (glejte poglavji 4.3 in 5.2).
English: some antibacterial drugs such as co-trimoxazole, ask your doctor if you are not sure)
Slovenian: • če ste alergični na (preobčutljivi za) druge derivate sulfonamida (npr. druge tiazide, nekatera protibakterijska zdravila, kot je ko-trimoksazol; če niste prepričani, vprašajte zdravnika).
English: Such conditions should be corrected before the administration of Cozaar Comp tablets (see sections 4.2. and 4.3.
Slovenian: Pred začetkom zdravljenja z zdravilom Cozaar Comp je treba ta stanja pozdraviti (glejte poglavji 4.2 in 4.3).
English: NAME OF THE MARKETING AUTHORISATION HOLDER [See Annex I - To be completed nationally] [For referral procedures]
Slovenian: IME IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM [Glejte dodatek 1 - Izpolni država članica]
English: Common: Abdominal pain, nausea, diarrhoea, dyspepsia Uncommon: Constipation, dental pain, dry mouth, flatulence, gastritis, vomiting
Slovenian: Bolezni prebavil pogoste: bolečine v trebuhu, navzea, diareja, dispepsija občasne: zaprtje, zobobol, suha usta, flatulenca, gastritis, bruhanje
English: • Swelling of the face, fever.
Slovenian: • otekanje obraza, zvišana telesna temperatura
English: Hyzaar Forte 100/25 mg
Slovenian: Madžarska Hyzaar Forte 100/25 mg Malta
English: Do not take Cozaar Comp
Slovenian: Ne jemljite zdravila Cozaar Comp:
English: Uncommon: Transient blurred vision, xanthopsia Vascular disorders
Slovenian: Očesne bolezni občasne: prehodno zamegljen vid, ksantopsija
English: When clinically appropriate direct change from monotherapy to the fixed combination may be considered in patients whose blood pressure is not adequately controlled.
Slovenian: Če je klinično primerno, lahko pri bolnikih, pri katerih krvni tlak ni ustrezno nadzorovan, takoj preidete z zdravljenja z eno učinkovino na zdravljenje s fiksno kombinacijo.
English: Cozaar Comp tablets may be taken with or without food.
Slovenian: Zdravilo Cozaar Comp se lahko zaužije s hrano ali na tešče.
English: Cozaar Comp tablets should be swallowed with a glass of water Cozaar Comp may be administered with or without food.
Slovenian: Cozaar Comp tablete je treba pogoltniti s kozarcem vode.
English: Both biliary and urinary excretion contribute to the elimination of losartan and its metabolites.
Slovenian: K izločanju losartana in njegovih presnovkov prispevata tako izložanje z žolčem kot izločanje skozi ledvice.
English: Cozaar Comp 50 mg/12.5 mg, Cozaar Comp 100 mg/12.5 mgand Cozaar Comp 100 mg/25 mg contain the following inactive ingredients: microcrystalline cellulose, lactose monohydrate, pregelatinized maize starch, magnesium stearate, hydroxypropyl cellulose, hypromellose.
Slovenian: Cozaar Comp 50 mg/12,5 mg, Cozaar Comp 100 mg/12,5 mg in Cozaar Comp 100 mg/25 mg vsebujejo naslednje pomožne snovi: mikrokristalno celulozo, laktozo monohidrat, predgeliran koruzni škrob, magnezijev stearat, hidroksipropilcelulozo, hipromelozo.
English: Losartan-Hydrochlorothiazide
Slovenian: Losartan-hidroklorotiazid
English: Further, as a result of its diuretic effect, hydrochlorothiazide increases plasma renin activity, increases aldosterone secretion, decreases serum potassium, and increases the levels of angiotensin II.
Slovenian: Rezultat diuretičnega delovanja hidroklorotiazida je povečanje plazemske reninske aktivnosti in sekrecije aldosterona, znižanje koncentracije kalija v serumu in povečanje koncentracije angiotenzina II.