FrancophonIA/ELRC3.0 huggingface dataset:
English: Relapse occurred <12 months Relapse occurred > = > 12 months a.
Croatian: Pojava relapsa <12 mjeseci Pojava relapsa > 12 mjeseci a.
English: However, chemical and physical in-use stability has been demonstrated for 24 hours at 2 °C-8 °C.
Croatian: Međutim, dokazana je kemijska i fizikalna stabilnost lijeka u primjeni tijekom 24 sata na temperaturi od 2 °C do 8 °C.
English: A negative JCV PCR does not exclude PML.
Croatian: Negativni JCV PCR ne isključuje PML.
English: White to off-white cake or powder.
Croatian: Bijeli do gotovo bijeli kolačić ili prašak.
English: Other medicines and Adcetris
Croatian: Drugi lijekovi i Adcetris
English: Your doctor will perform regular blood tests to make sure that it is safe for you to receive this medicine.
Croatian: Liječnik će Vam redovito raditi krvne pretrage kako bi provjerio da možete sigurno nastaviti primati ovaj lijek.
English: MMAE is further metabolised mainly to an equally potent metabolite; however, its exposure is an order of magnitude lower than that of MMAE.
Croatian: MMAE se dalje metabolizira pretežno u jednako potentan metabolit; međutim, izloženost njemu je za red veličine niža nego ona za MMAE.
English: Currently available data are described in sections 4.8, 5.1 and 5.2.
Croatian: Trenutno dostupni podaci su opisani su u dijelovima 4.8, 5.1 i 5.2.
English: In vitro, the binding of MMAE to human serum plasma proteins ranged from 68-82%.
Croatian: In vitro, vezanje MMAE za proteine plazme u ljudskom serumu kretalo se u rasponu od 68% do 82%.
English: Eligible patients were required to have at least one of the following risk factors:
Croatian: Kriterij za uključenje bolesnika bio je postojanje najmanje jednog od sljedećih rizičnih čimbenika:
English: The efficacy results are shown in Table 7.
Croatian: Rezultati djelotvornosti prikazani su u tablici 7.
English: Early (IA-IIA)
Croatian: Početni (IA-IIA)
English: In the study, patients were to receive their first dose after recovery from ASCT (between days 30-45 following ASCT).
Croatian: U ispitivanju su bolesnici trebali primiti svoju prvu dozu nakon oporavka od ASCT-a (između 30-45 dana od ASCT-a).
English: MMAE did not induce any major CYP450 enzymes in primary cultures of human hepatocytes.
Croatian: MMAE nije inducirao glavne enzime CYP450 u primarnim kulturama ljudskih hepatocita.
English: Post-hoc analyses were performed to evaluate the impact of increased risk (number of risk factors) on clinical benefit (Table 8).
Croatian: Provedene su post-hoc analize kako bi se ocijenio utjecaj povećanog rizika (broja rizičnih čimbenika) na kliničku korist (tablica 8).
English: It is not known how frequently infusion-related reactions to this medicine are serious or fatal.
Croatian: Nije poznato koliko su često reakcije povezane s infuzijom ovog lijeka ozbiljne ili imaju smrtni ishod.
English: Tell your doctor if you are taking any other medicines, if you have taken any recently, or if you start taking new ones.
Croatian: Obavijestite svog liječnika ako uzimate, nedavno ste uzeli ili počinjete uzimati nove lijekove.
English: Advanced (IIB-IVB pcALCL, n (%)
Croatian: Uznapredovali (IIB-IVB pcALCL, n (%)
English: Median per Investigator
Croatian: Medijan po ispitivaču
English: What Adcetris is and what it is used for
Croatian: Što je Adcetris i za što se koristi
English: If a pregnant woman needs to be treated she should be clearly advised on the potential risk to the foetus.
Croatian: Ako je trudnicu potrebno liječiti, treba je jasno upozoriti na moguće rizike za fetus.
English: Partial Response
Croatian: Djelomičan odgovor
English: Total storage time of the solution from reconstitution to infusion should not exceed 24 hours.
Croatian: Ukupno vrijeme čuvanja otopine od rekonstitucije do infuzije ne smije biti dulje od 24 sata.
English: HL at increased risk of relapse or progression
Croatian: HL s povećanim rizikom od relapsa ili progresije bolesti
English: These data suggest that efficacy and safety can be extrapolated to other CTCL CD30+ subtypes.
Croatian: Ovi podaci upućuju da se djelotvornost i sigurnost mogu ekstrapolirati na druge podtipove CD30+ CTCL-a.
English: If you think you have previously had a similar reaction, tell your doctor BEFORE you are given this medicine.
Croatian: Ako mislite da ste prethodno imali sličnu reakciju, obavijestite svog liječnika PRIJE nego što dobijete ovaj lijek.
English: Like all medicines, this medicine may cause side effects, although not everybody gets them.
Croatian: Kao i svi lijekovi, ovaj lijek može uzrokovati nuspojave iako se one neće javiti kod svakoga.
English: Do NOT use Adcetris if you:
Croatian: NEMOJTE primjenjivati Adcetris:
English: This medicine has been given ‘conditional approval'.
Croatian: Ovom lijeku izdano je ‘uvjetno odobrenje'.
English: The safety profile in elderly patients was consistent with that of adult patients.
Croatian: Sigurnosni profil lijeka u starijih bolesnika je bio konzistentan s onim u odraslih bolesnika.
English: Data in HL Patients Who Are Not Stem Cell Transplant (SCT) Candidates
Croatian: Podaci za bolesnike s HL koji nisu kandidati za transplantiranje matičnih stanica (SCT)
English: If you develop infusion reactions (as stated previously), your doctor may stop giving this medicine and start support treatment.
Croatian: Ako razvijete reakcije na infuziju (kako je prethodno navedeno), liječnik može zaustaviti primjenu ovog lijeka i započeti potporno liječenje.
English: For single use only
Croatian: Samo za jednokratnu uporabu.
English: Pharmacokinetics in special populations
Croatian: Farmakokinetika kod posebnih populacija
English: What Adcetris looks like and contents of the pack
Croatian: Kako Adcetris izgleda i sadržaj pakiranja
English: MMAE does not inhibit other isoforms.
Croatian: MMAE ne inhibira druge izoforme.
English: Of these 33 patients who received the RP2D, 32 were evaluable for response.
Croatian: Od 33 bolesnika koji su primili RP2D, odgovor je bilo moguće procijeniti kod 32.
English: • Relapsed or progressive HL that occurred <12 months from the end of frontline treatment
Croatian: • Relapsni ili progresivni HL koji se dogodio < 12 mjeseci od završetka prve linije liječenja
English: Women must continue using contraception for 6 months following the last dose of Adcetris.
Croatian: Žene moraju nastaviti koristiti kontracepciju tijekom 6 mjeseci nakon posljednje doze lijeka Adcetris.
English: Fatal outcomes have been reported.
Croatian: Prijavljeni su smrtni ishodi.
English: Of the ITT population, 846 patients (64%) had Stage IV disease.
Croatian: U ITT populaciji bilo je 846 bolesnika (64%) sa 4. stadijem bolesti.
English: These infusion reactions can be serious or even fatal (known as an anaphylactic reaction).
Croatian: Reakcije na infuziju mogu biti ozbiljne ili čak smrtonosne (poznate kao anafilaktička reakcija).
English: Patients with Stage IV Disease
Croatian: Bolesnici s bolesti u 4. stadiju
English: You may experience the following side effects:
Croatian: Možete osjetiti sljedeće nuspojave:
English: Patients should be carefully monitored during treatment for the emergence of possible serious and opportunistic infections.
Croatian: Bolesnike treba pažljivo nadzirati tijekom liječenja zbog moguće pojave ozbiljnih i oportunističkih infekcija.
English: For further efficacy results, see Table 12 and Figure 5.
Croatian: Za daljnje rezultate o djelotvornosti, vidjeti tablicu 12 i sliku 5.
English: Patients should be carefully monitored during and after infusion.
Croatian: Bolesnike treba pažljivo nadzirati tijekom i nakon infuzije.
English: Rash a, pruritus
Croatian: Osip a, pruritus
English: 27.9 months
Croatian: 27,9 mjeseci
English: Per Ann Arbor Staging IPFP = International Prognostic Factor Project
Croatian: Određivanje stadija prema Ann Arbor IPFP = Međunarodni projekat za procjenu prognostičkih faktora
English: Proper aseptic technique throughout the handling of this medicinal product should be followed.
Croatian: Potrebno je pridržavati se ispravne aseptičke tehnike cijelo vrijeme tijekom rukovanja ovim lijekom.
English: After reconstitution/dilution, from a microbiological point of view, the product should be used immediately.
Croatian: Nakon rekonstitucije/razrjeđivanja, s mikrobiološkog stajališta, lijek je potrebno odmah primijeniti.
English: The infusion may be restarted at a slower rate after symptom resolution.
Croatian: Infuzija se može ponovno započeti manjom brzinom nakon povlačenja simptoma.
English: For refractory disease, or upon progression or relapse after frontline therapy.
Croatian: Za refraktornu bolest ili nakon progresije ili relapsa nakon prve linije liječenja.
English: A decision should be made whether to discontinue breast-feeding or to discontinue/abstain from this therapy, taking into account a potential risk of breast-feeding for the child and the benefit of therapy for the woman.
Croatian: Potrebno je odlučiti treba li prekinuti dojenje ili prekinuti liječenje/suzdržati se od liječenja ovim lijekom, uzimajući u obzir mogući rizik dojenja za dijete i korist liječenja za ženu.
English: Direct the stream toward the wall of the vial and not directly at the cake or powder.
Croatian: Usmjerite mlaz prema stijenci bočice, a ne izravno u kolačić ili prašak.
English: Grade 2 (interfering with function but not with activities of daily living) or
Croatian: Stupanj 2 (smanjenje funkcionalnih sposobnosti, ali ne i aktivnosti u svakodnevnom životu) ili
English: Pre-existing liver disease, comorbidities, and concomitant medications may also increase the risk.
Croatian: Već postojeća bolest jetre, komorbiditeti i istodobno primijenjeni lijekovi također mogu povećati rizik.
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached
Croatian: • Prilikom svake izmjene sustava za upravljanje rizicima, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik, odnosno kada je izmjena rezultat ostvarenja nekog važnog cilja (u smislu farmakovigilancije ili smanjenja rizika).
English: Takeda Austria GmbH St. Peter-Straβe 25 A-4020 Linz Austria
Croatian: Takeda Austria GmbH St. Peter-Straβe 25 A-4020 Linz Austrija
English: 40.5 months
Croatian: 40,5 mjeseci
English: Grade 3 (interfering with activities of daily living)
Croatian: Stupanj 3 (smanjenje aktivnosti u svakodnevnom životu)
English: Patient weight (kg)
Croatian: Tjelesna težina bolesnika (kg)
English: This is equivalent to 0.7% of the recommended maximum daily dietary intake of sodium for an adult.
Croatian: To odgovara 0,7% preporučenog maksimalnog dnevnog unosa soli za odrasle osobe.
English: One patient in each arm had incomplete staging data and are not included in the table
Croatian: Po jedan bolesnik u svakoj skupini nije imao kompletne podatke o stadiju, stoga nisu uključeni u tablicu
English: Disease control rate (CR + PR + SD) Duration of response
Croatian: Stopa kontrole bolesti (CR + PR + SD) Trajanje odgovora
English: Adcetris is to be given to adults only.
Croatian: Adcetris se daje samo odraslima.
English: Your treatment may influence your ability to drive or operate machines.
Croatian: Liječenje može utjecati na Vašu sposobnost upravljanja vozilima i rada sa strojevima.
English: The investigator assessments were generally consistent with the independent review of the scans.
Croatian: Procjene ispitivača bile su općenito sukladne neovisnoj procjeni snimki.
English: Testicular atrophy and degeneration were partially reversible following a 16-week treatment-free period.
Croatian: Atrofija i degeneracija testisa bile su djelomično reverzibilne nakon razdoblja bez liječenja u trajanju od 16 tjedana.
English: - If you have any further questions, ask your doctor.
Croatian: - Ako imate dodatnih pitanja, obratite se svom liječniku.
English: Fifty nine percent (59%) of patients had advanced stage disease (Stage III or IV) at initial diagnosis.
Croatian: Pedeset devet posto (59%) bolesnika imalo je bolest u uznapredovalom stadiju (Stadij III ili IV) u vrijeme postavljanja dijagnoze.
English: Your doctor or nurse will also monitor you during and after the infusion.
Croatian: Lijek će Vam dati liječnik ili medicinska sestra koji će Vas i nadzirati tijekom i nakon infuzije.
English: ADCETRIS should not be used during pregnancy unless the benefit to the mother outweighs the potential risks to the foetus.
Croatian: ADCETRIS se ne smije primjenjivati tijekom trudnoće osim ako je korist za majku veća od mogućih rizika za fetus.
English: The physician should be particularly alert to symptoms suggestive of PML that the patient may not notice (e.g., cognitive, neurological, or psychiatric symptoms).
Croatian: Liječnik treba obratiti posebnu pažnju na simptome koji mogu upućivati na PML, a koje bolesnik možda nije uočio (npr. kognitivni, neurološki ili psihijatrijski simptomi).
English: Your doctor may lower your starting dose to 1.2 mg/kg if you have kidney or liver problems.
Croatian: Liječnik može smanjiti početnu dozu na 1,2 mg/kg ako imate probleme s bubrezima ili jetrom.
English: Severe and prolonged (≥ 1 week) neutropenia can occur with this treatment which may increase the risk of patients developing serious infections.
Croatian: Uz ovo liječenje može nastati teška i dugotrajna (≥ 1 tjedna) neutropenija koja u bolesnika može povećati rizik od razvoja ozbiljnih infekcija.
English: Estimated mPFS
Croatian: Procijenjena mPFS
English: Prior ASCT
Croatian: Prethodni ASCT
English: Name and address of the manufacturers of the biological active substance
Croatian: Nazivi i adrese proizvođača biološke djelatne tvari
English: 6.7 months
Croatian: 6,7 mjeseci
English: ADCETRIS dose (mg/kg) x patient's body weight (kg)
Croatian: Doza lijeka ADCETRIS (mg/kg) x tjelesna težina bolesnika (kg)
English: Patients who develop Grade 3 or Grade 4 lymphopenia may continue treatment without interruption.
Croatian: Bolesnici koji razviju stupanj 3 ili stupanj 4 limfopenije mogu nastaviti liječenje bez prekida.
English: The influence of age on pharmacokinetics was investigated in each analysis and it was not a significant covariate.
Croatian: Utjecaj dobi na farmakokinetiku ispitan je u svakoj analizi i ne predstavlja značajnu kovarijancu.
English: The frequency of unique serious adverse drug reactions was ≤ 1%.
Croatian: Učestalost jedinstvenih ozbiljnih nuspojava lijeka bila je ≤ 1%.
English: The levels of MMAE metabolites have not been measured in human plasma.
Croatian: Razine metabolita MMAE nisu izmjerene u ljudskoj plazmi.
English: The median time from onset to resolution or improvement for all events ranged from 16 to 23.4 weeks.
Croatian: Medijan razdoblja od početka do povlačenja ili poboljšanja za sve događaje bio je u rasponu od 16 do 23,4 tjedana.
English: The RP2D was determined to be 1.8 mg/kg.
Croatian: Utvrđen je RP2D od 1,8 mg/kg.
English: ADCETRIS should be administered through a dedicated intravenous line and it must not be mixed with other medicinal products (see section 6.2).
Croatian: ADCETRIS treba primijeniti kroz posebnu intravensku liniju i ne smije se miješati s drugim lijekovima (vidjeti dio 6.2).
English: Best clinical response (n = 102 )
Croatian: Najbolji klinički odgovor (n = 102 )
English: Best response to salvage therapy pre-ASCT Complete Response
Croatian: Najbolji odgovor na terapiju spasa prije ASCT-a
English: After the first dose of Adcetris in combination with chemotherapy, your doctor may also give you a medicine that will help prevent development or reduce the severity of neutropenia (decrease of white blood cell count) which can increase the risk of infection.
Croatian: Nakon primanja prve doze lijeka Adcetris u kombinaciji s kemoterapijom, liječnik vam može dati i lijek koji će pomoći spriječiti razvoj ili smanjiti težinu neutropenije (smanjen broj bijelih krvnih stanica) koja može povećati rizik od infekcije.
English: Based on population PK estimation the typical apparent central volume of distribution of MMAE was 35.5 l
Croatian: Na temelju procjene populacijske farmakokinetike, tipični prividni centralni volumen distribucije za MMAE bio je 35,5 l.
English: See the fertility section below pertaining to advice for women whose male partners are being treated with ADCETRIS.
Croatian: Vidjeti niže dio o plodnosti, koji se odnosi na savjete ženama čiji se partneri liječe lijekom ADCETRIS.
English: These features make CD30 a target for therapeutic intervention.
Croatian: Zbog toga je biljeg CD30 pogodna meta za terapijske intervencije.
English: MMAE is a substrate of CYP3A4 and possibly CYP2D6.
Croatian: MMAE je supstrat CYP3A4 i moguće CYP2D6.
English: This medicinal product has been authorised under a so-called ‘conditional approval' scheme.
Croatian: Ovaj lijek je odobren po shemi takozvanog ‘uvjetnog odobrenja'.
English: In the first cycle, higher MMAE exposure was associated with an absolute decrease in neutrophil count.
Croatian: U prvom ciklusu, veća izloženost MMAE bila je povezana s apsolutnim sniženjem broja neutrofila.
English: (95% CI [0.40, 0.81]) Stratified log-rank test p=0.001
Croatian: (95% CI [0,40; 0,81]) Stratificirani log-rang test p=0,001
English: Reconstituted/diluted solution: Use immediately or store in a refrigerator (2 C-8 °C) and use within 24 hours.
Croatian: Pripremljena/razrijeđena otopina: Primijeniti odmah ili čuvati u hladnjaku (2 C-8 °C) i primijeniti u roku od 24 sata.
English: CTCL is a cancer of a certain type of white blood cell called a ‘T-cell' that mainly affects the skin.
Croatian: CTCL je rak određene vrste bijelih krvnih stanica pod nazivom „T-stanice“, koji uglavnom zahvaća kožu.
English: Treatment should be continued until disease progression or unacceptable toxicity(see section 4.4).
Croatian: Liječenje treba nastaviti do progresije bolesti ili do pojave neprihvatljive toksičnosti (vidjeti dio 4.4).
English: Objective Response Rate lasting at least 4 months (ORR4) per IRF n (%)
Croatian: Objektivna stopa odgovora koja traje najmanje 4 mjeseca (ORR4) po IRF-u n (%)
English: In vitro, MMAE was a substrate of P-gp and was not an inhibitor of P-gp at clinical concentrations.
Croatian: In vitro, MMAE je bio supstrat P-gp i nije inhibirao P-gp u kliničkim koncentracijama.
English: MMAE is not likely to displace or to be displaced by highly protein-bound medicines.
Croatian: MMAE najvjerojatnije neće istisnuti lijekove ili biti istisnut lijekovima koji se u visokom postotku vežu za proteine.
English: These results were consistent with the pharmacological effect of MMAE on the mitotic apparatus (disruption of the microtubule network) in cells.
Croatian: Ovi su rezultati u skladu s farmakološkim učinku MMAE na mitotički aparat (razdor mreže mikrotubula) u stanicama.
English: Within each System Organ Class, adverse reactions are listed under frequency categories of: Very common (≥ 1/10); Common (≥ 1/100 to < 1/10); Uncommon (≥ 1/1,000 to < 1/100); Rare (≥ 1/10,000 to < 1/1,000); Very rare (< 1/10,000); not known (cannot be estimated from the available data).
Croatian: Unutar svake klase organskog sustava, nuspojave su navedene prema kategorijama učestalosti: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000), nepoznata učestalost (ne može se procijeniti iz dostupnih podataka).
English: Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/
Croatian: Detaljnije informacije o ovom lijeku dostupne su na internetskoj stranici Europske agencije za lijekove: http://www.ema.europa.eu
English: Premedication may include paracetamol, an antihistamine and a corticosteroid.
Croatian: Premedikacija može uključivati paracetamol, antihistaminike i kortikosteroide.
English: The median time from initial sALCL diagnosis to first dose with ADCETRIS was 16.8 months.
Croatian: Medijan vremena od početne dijagnoze sALCL do prve doze lijeka ADCETRIS iznosio je 16,8 mjeseci.
English: What Adcetris contains
Croatian: Što Adcetris sadrži
English: Patients should be monitored during and after infusion (see section 4.4).
Croatian: Bolesnike treba nadzirati tijekom i nakon infuzije (vidjeti dio 4.4).
English: Table 5 provides the efficacy results for modified PFS and overall survival (OS) in the ITT population and patients with Stage IV disease.
Croatian: Tablici 5 prikazani su rezultati djelotvornosti prema modificiranom PFS i ukupnom preživljenju (OS) u ITT populaciji i u bolesnika s bolesti u 4. stadiju.
English: Post-hoc Risk Factor Analyses
Croatian: Post-hoc analiza čimbenika rizika
English: PML is a rare demyelinating disease of the central nervous system that results from reactivation of latent JCV and is often fatal.
Croatian: PML je rijetka demijelinizirajuća bolest središnjeg živčanog sustava koja nastaje zbog reaktivacije latentnog JCV i često ima smrtni ishod.
English: This medicine contains 13.2 mg sodium (main component of cooking/table salt) in each vial.
Croatian: Ovaj lijek sadrži 13,2 mg natrija (glavni sastojak kuhinjske soli) u jednoj bočici.
English: Stable Disease
Croatian: Stabilna bolest
English: Best clinical response (n = 58 )
Croatian: Najbolji klinički odgovor (n = 58 )
English: Calculation to determine the total number of ADCETRIS vials needed:
Croatian: Izračun za određivanje ukupnog broja potrebnih bočica lijeka ADCETRIS:
English: Excipient with known effect
Croatian: Pomoćne tvari s poznatim učinkom
English: You should not use this medicine if you are pregnant unless you and your doctor decide that the benefit to you outweighs the potential risk to the unborn baby.
Croatian: Ne smijete primjenjivati ovaj lijek ako ste trudni osim ako se u dogovoru s Vašim liječnikom ne odlučite da je korist od liječenje za Vas veća od mogućeg rizika za nerođeno dijete.
English: The ADC is expected to be catabolised as a protein with component amino acids recycled or eliminated.
Croatian: Očekuje se da će ADC biti kataboliziran kao protein uz recikliranje ili eliminaciju sastavnih aminokiselina.
English: At least one metabolite of MMAE has been shown to be active in vitro.
Croatian: Pokazalo se da je najmanje jedan metabolit MMAE djelatan in vitro.
English: Median ADC AUC in children and adolescents from this study was approx. 14% and 3% lower than in adult patients, respectively, while MMAE exposures were 53% lower and 13% higher, respectively, than in adult patients.
Croatian: Medijan AUC-a za ADC u djece i adolescenata iz ovog ispitivanja bio je približno 14% odnosno 3% niži nego u odraslih bolesnika, dok su izloženosti MMAE bile 53% niže odnosno 13% više nego u odraslih bolesnika.
English: There are no data from the use of ADCETRIS in pregnant women.
Croatian: Nema podataka o primjeni lijeka ADCETRIS u trudnica.
English: If you have any questions on the use of this medicine, ask the doctor or nurse who is giving you the infusion.
Croatian: U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka, obratite se svom liječniku ili medicinskoj sestri koji Vam daju infuziju.
English: ADCETRIS treatment should start following recovery from ASCT based on clinical judgment.
Croatian: Terapiju lijekom ADCETRIS treba započeti nakon oporavka od ASCT-a temeljem kliničke procjene.
English: Toxic epidermal necrolysis was not reported in the combination therapy setting.
Croatian: Toksična epidermalna nekroliza nije zabilježena tijekom primjene kombinirane terapije.
English: Symptoms of an anaphylactic reaction may include, but are not limited to, urticaria, angioedema, hypotension and bronchospasm.
Croatian: Simptomi anafilaktičke reakcije mogu uključivati, ali nisu ograničeni na urtikariju, angioedem, hipotenziju i bronhospazam.
English: Exposures were approximately dose proportional with a trend observed for lower ADC exposures at lower ages/ body weights in the study population.
Croatian: Izloženosti su bile približno proporcionalne dozi uz opažen trend niže izloženosti ADC-u u mlađoj životnoj dobi / nižoj tjelesnoj težini u ispitivanoj populaciji.