FrancophonIA/ELRC3.0 huggingface dataset:
English: Table 5 Best tumour response in trial STIB2222 (GIST)
Croatian: Tablica 5 Najbolji tumorski odgovor u ispitivanju STIB2222 (GIST)
English: * Full follow-up period; NE - Not estimable
Croatian: * Potpuni period praćenja; NP - nije moguće procijeniti
English: Mitotic index data were available for 556 of the 713 intention-to-treat (ITT) population.
Croatian: Podaci o mitotskom indeksu su bili dostupni za 556 od 713 bolesnika u populaciji planiranoj za liječenje (ITT - engl. intention-to-treat).
English: If you are not able to take the medicine as your doctor prescribed or you feel you do not need it anymore, contact your doctor straight
Croatian: Ako niste u mogućnosti uzimati ovaj lijek kako Vam je liječnik propisao ili ako osjećate da Vam više ne treba, odmah se obratite svom liječniku.
English: Patients who have a low or very low risk of recurrence should not receive adjuvant treatment.
Croatian: Bolesnici s niskim ili vrlo niskim rizikom od recidiva ne bi trebali primati adjuvantno liječenje.
English: Older people: Imatinib pharmacokinetics have not been specifically studied in older people.
Croatian: Starije osobe: Farmakokinetika imatiniba nije specifično ispitivana u starijih osoba.
English: • Unexpected bleeding or bruising (when you have not hurt yourself).
Croatian: • Neočekivano krvarenje ili pojava masnica (kada se niste ozlijedili).
English: It arises from uncontrolled cell growth of the supporting tissues of these organs.
Croatian: Nastaje zbog nekontroliranog rasta stanica potpornog tkiva tih organa.
English: A significant number of patients who had stable disease at the time of the interim analysis achieved a partial response with longer treatment (median follow-up 31 months).
Croatian: Značajan broj bolesnika koji je imao stabilnu bolest u vrijeme interim analize je postigao djelomični odgovor s dužim liječenjem (medijan praćenja od 31 mjeseca).
English: The median overall survival has not been reached.
Croatian: Medijan vrijednosti ukupnog preživljenja nije dosegnut.
English: All doses (n=147) 400 mg (n=73) 600 mg (n=74) n (%)
Croatian: Sve doze (n=147) 400 mg (n=73) 600 mg (n=74) n (%)
English: The results of subgroup analyses according to the United States National Institutes of Health (NIH) and the Armed Forces Institute of Pathology (AFIP) risk classifications are shown in Table 6.
Croatian: Rezultati analize podskupine bolesnika razvrstane prema klasifikacijama rizika američkog Nacionalnog instituta za zdravstvo (NIH - National Institutes of Health) i Instituta za patologiju američkih oružanih snaga (AFIP - Armed Forces Institute of Pathology) su prikazani u Tablici 6.
English: Therefore, the use of imatinib in combination requires special precaution.
Croatian: Stoga primjena imatiniba u kombinaciji zahtijeva posebne mjere
English: No benefit was observed in the low and very low risk groups.
Croatian: U skupinama s niskim ili vrlo niskim rizikom nije uočena korist.
English: A major response combines both complete and partial responses: complete (0% Ph+ metaphases),
Croatian: Veliki odgovor je kombinacija potpunih i djelomičnih odgovora: potpuni (0% Ph+ metafaza),
English: However, these associations are not sufficiently pronounced to warrant dose adjustment.
Croatian: No, te veze nisu dovoljno izražene da bi opravdale prilagođavanje doze.
English: Haematological experts in the management of this disease should supervise the therapy throughout all phases
Croatian: Specijalisti hematolozi uključeni u liječenje ove bolesti trebaju nadzirati terapiju kroz sve faze
English: Your doctor has prescribed Imatinib Teva B.V. because you suffer from a serious condition.
Croatian: Vaš liječnik je propisao Imatinib Teva B.V., jer patite od ozbiljnog stanja.
English: GIST is a cancer of the stomach and bowels.
Croatian: GIST je rak želuca i crijeva.
English: • Recurrence (reactivation) of hepatitis B infection when you have had hepatitis B in the past (a liver
Croatian: • Ponovna pojava (ponovna aktivacija) infekcije virusom hepatitisa B ako ste u prošlosti imali hepatitis B (infekciju jetre).
English: Pharmacotherapeutic group: Protein kinase inhibitors, ATC code: L01XE01
Croatian: Farmakoterapijska skupina: Inhibitori protein kinaze, ATK oznaka: L01XE01
English: 2031GA Haarlem Netherlands
Croatian: 2031 GA Haarlem
English: The daily dose was escalated to 800 mg in a total of 103 patients; 6 patients achieved a partial response and 21 stabilisation of their disease after dose escalation for an overall clinical benefit of 26%.
Croatian: Dnevna doza je povećana na 800 mg kod ukupno 103 bolesnika; 6 bolesnika je postiglo djelomični odgovor, a 21 stabilizaciju njihove bolesti nakon povećanja doze, uz ukupnu kliničku korist od 26%.
English: Decreased values of albumin caused a reduced clearance (CL/f); and higher levels of WBC led to a reduction of CL/f.
Croatian: Smanjene vrijednosti albumina uzrokovale su smanjeni klirens (CL/f); a više WBC razine su dovele do smanjenja CL/f vrijednosti.
English: Length of treatment in the clinical trial supporting this indication was 36 months (see section 5.1).
Croatian: Duljina liječenja u kliničkom ispitivanju vezanom uz ovu indikaciju bila je 36 mjeseci (vidjeti dio 5.1).
English: However if it is nearly time for the next dose, - Then continue with your normal schedule.
Croatian: Međutim, ako je uskoro vrijeme za sljedeću dozu, preskočite propuštenu dozu.
English: The safety and efficacy of imatinib in children with MDS/MPD, DFSP, GIST and HES/CEL aged less than 18 years of age have not been established in clinical trials.
Croatian: Sigurnost i djelotvornost imatiniba u djece s MDS/MPB-om, DFSP-om, GIST-om i HES/KEL-om mlađe od 18 godina nisu ustanovljene u kliničkim ispitivanjima.
English: Some children and adolescents taking Imatinib Teva B.V. may have slower than normal growth.
Croatian: Kod neke djece i adolescenata koji uzimaju Imatinib Teva B.V. rast može biti sporiji od normalnog.
English: 8 to 10 g (single dose): Vomiting and gastrointestinal pain have been reported.
Croatian: 8 g do 10 g (jednokratna doza): zabilježeni su povraćanje i bolovi u trbuhu.
English: The amount of Imatinib Teva B.V. given will depend on your child's condition, body weight and height.
Croatian: Količina Imatiniba Teva B.V.koju je potrebno dati ovisiti će o stanju djeteta, tjelesnoj težini i visini.
English: All treatment regimens include administration of steroids for CNS prophylaxis.
Croatian: Svi terapijski protokoli uključuju primjenu steroida radi profilakse CNS-a.
English: The risk of recurrence in patients after surgery of their primary GIST was retrospectively assessed based on the following prognostic factors: tumour size, mitotic index, tumour location.
Croatian: Rizik od recidiva bolesti u bolesnika nakon kirurškog uklanjanja primarnog GIST-a je retrospektivno procijenjen na temelju sljedećih prognostičkih faktora: veličina tumora, mitotski indeks, lokacija tumora.
English: All patients received imatinib and consolidation chemotherapy (see Table 3) after induction and the levels of bcr-abl transcripts were identical in the two arms at 8 weeks.
Croatian: Svi su bolesnici primili imatinib i konsolidacijsku kemoterapiju (vidjeti Tablicu 3) nakon indukcije, a razine bcr-abl prijepisa bile su identične u oba kraka nakon 8 tjedana.
English: In all clinical studies 38-40% of patients were ≥ 60 years of age and 10-12% of patients were ≥ 70 years of
Croatian: U svim kliničkim ispitivanjima 38-40 % bolesnika bilo je u dobi ≥60 godina, a 10-12% bolesnika bilo je u dobi ≥70 godina.
English: Non-neoplastic lesions not identified in earlier preclinical studies were the cardiovascular system, pancreas, endocrine organs and teeth.
Croatian: Neneoplastičke lezije koje nisu identificirane u prethodnim pretkliničkim ispitivanjima javile su se u kardiovaskularnom sustavu, gušterači, endokrinim organima i zubima.
English: 12 months 24 months
Croatian: 24 mjeseci
English: The risk of recurrence was thus reduced by approximately 89% as compared with placebo (hazard ratio = 0.113 [0.049-0.264]).
Croatian: Rizik od recidiva bolesti je smanjen za otprilike 89% u usporedbi s placebom (omjer rizika = 0,113 [0,049-0,264]).
English: If you have any questions about how Imatinib Teva B.V. works or why this medicine has been prescribed for you, ask your doctor.
Croatian: Ako imate bilo kakvih pitanja o tome na koji način djeluje Imatinib Teva B.V., ili zašto je taj lijek Vama propisan, obratite se svom liječniku.
English: In 61 of these 117 patients FIP1L1-PDGFRα fusion kinase was identified.
Croatian: U 61 od tih 117 bolesnika identificirana je fuzijska kinaza FIP1L1-PDGFRα.
English: The effect of stopping treatment after achieving a response has not been investigated.
Croatian: Učinak prekida liječenja nakon postizanja odgovora nije ispitivan.
English: Women of childbearing potential must be advised to use effective contraception during treatment.
Croatian: Žene reproduktivne dobi treba savjetovati da koriste učinkovitu kontracepciju tijekom liječenja.
English: At the time of analysis, the treatment duration was a median of 7 months (7 days to 13 months).
Croatian: U vrijeme provođenja analize, medijan trajanja liječenja iznosio je 7 mjeseci (7 dana do 13 mjeseci).
English: Name and address of the manufacturers responsible for batch release Teva Czech Industries s.r.o.
Croatian: Naziv i adresa proizvođača odgovornih za puštanje serije lijeka u promet Teva Czech Industries s.r.o.
English: Store below 30°C
Croatian: Čuvati na temperaturi ispod 30°C.
English: These patients ranged in age from 18 to 83 years old and had a pathologic diagnosis of Kit-positive malignant GIST that was unresectable and/or metastatic.
Croatian: Dob se tih bolesnika kretala od 18 do 83 godine, a imali su patološku dijagnozu Kit-pozitivnog malignog GIST-a koji je bio inoperabilan i/ili metastatski.
English: The median time of follow-up was 54 months (from date of randomisation to data cut-off), with a total of 83 months between the first patient randomised and the cut-off date.
Croatian: Medijan vremena praćenja bio je 54 mjeseca (od datuma randomizacije do završetka prikupljanja podataka), pri čemu je od randomizacije prvog bolesnika do završetka prikupljanja podataka prošlo 83 mjeseca.
English: - If you are being treated for HES/CEL:
Croatian: Ako se liječite zbog HES/KEL-a:
English: Treatment with imatinib may be interrupted or the dose may be reduced, as recommended in section
Croatian: Liječenje imatinibom može se prekinuti ili se doza može smanjiti, kao što je preporučeno u dijelu 4.2.
English: Do not stop taking Imatinib Teva B.V. unless your doctor tells you to.
Croatian: Nemojte prestati uzimati Imatinib Teva B.V., osim ako Vam to ne kaže liječnik.
English: C/C, n. 4, Poligono Industrial Malpica
Croatian: 4, Poligono Industrial Malpica
English: Check with your doctor or pharmacist if you are
Croatian: Provjerite s liječnikom ili ljekarnikom ako niste sigurni.
English: Five (5) patients responded, 3 completely and 2 partially.
Croatian: 5 bolesnika je imalo odgovor, 3 kompletni i 2 parcijalni.
English: If it is used during pregnancy, the patient must be informed of the potential risk to the foetus.
Croatian: Ako se primjenjuje tijekom trudnoće, bolesnica mora biti informirana o potencijalnom
English: In children and adolescents, Imatinib Teva B.V. can be used in different phases of the disease (chronic, accelerated phase and blast crisis).
Croatian: U djece i adolescenata, Imatinib Teva B.V. se može koristiti u različitim fazama bolesti (kronična, ubrzana faza i blastična kriza).
English: In clinical trials, there was an increased incidence of these events in older people and those with a prior history of cardiac disease.
Croatian: U kliničkim je ispitivanjima zabilježena povećana incidencija tih događaja u starijih osoba te u onih s anamnezom srčanih bolesti.
English: The experience with imatinib in patients with MDS/MPD associated with PDGFR gene re-arrangements is very limited (see section 5.1).
Croatian: Iskustvo s imatinibom u bolesnika s MDS/MPB-om povezanim s preuredbom gena za PDGFR je vrlo ograničeno (vidjeti dio 5.1).
English: Following oral administration in healthy volunteers, the t½ was approximately 18 h, suggesting that oncedaily dosing is appropriate.
Croatian: Nakon peroralne primjene u zdravih dobrovoljaca, t½ bilo je oko 18 h, što navodi na zaključak da je doziranje jedanput na dan primjereno.
English: For CML and GIST, your doctor may prescribe a higher or lower dose depending on how you respond to treatment.
Croatian: Liječnik Vam za KML i GIST može propisati višu ili nižu dozu, ovisno o tome kako reagirate na liječenje.
English: The most important changes included cardiac hypertrophy and dilatation, leading to signs of cardiac insufficiency in some animals.
Croatian: Najvažnije promjene uključivale su srčanu hipertrofiju i dilataciju, što je, u nekih životinja, dovelo do znakova srčane
English: Figure 2 Kaplan-Meier estimates for overall survival (ITT population)
Croatian: Kaplan-Meierova procjena ukupnog preživljenja (ITT populacija)
English: The long-term effects of prolonged treatment with imatinib on growth in children are unknown.
Croatian: Nisu poznati dugoročni učinci produljene terapije imatinibom na rast djece.
English: Based on preliminary population pharmacokinetic analysis in GIST patients, there were three variables (albumin, WBC and bilirubin) found to have a statistically significant relationship with imatinib pharmacokinetics.
Croatian: Na temelju preliminarne analize populacijske farmakokinetike u bolesnika s GIST-om, utvrđeno je da tri varijable (albumin, WBC i bilirubin) imaju statistički značajan odnos s farmakokinetikom imatiniba.
English: When the response rate is calculated from patients with at least one valid assessment, the response rate for CHR, CCyR and MR was 20/22 (90.9%), 9/9 (100%) and 11/17
Croatian: Kad se stopa odgovora računa u bolesnika s barem jednom valjanom procjenom, stopa odgovora za CHR, CCyR i MR bila je 20/22 (90,9%), 9/9 (100%) odnosno 11/17 (64,7%).
English: Limited data exist on the effect of dose increases from 400 mg to 600 mg or 800 mg in patients progressing at the lower dose (see section 5.1).
Croatian: Postoje ograničeni podaci o učinku povećanja doze s 400 mg na 600 mg ili 800 mg u bolesnika u kojih do progresije dolazi uz nižu dozu (vidjeti dio 5.1).
English: Myeloid blast crisis: 260 patients with myeloid blast crisis were enrolled.
Croatian: Mijeloična blastična kriza: ispitivanje je uključeno 260 bolesnika s mijeloičnom blastičnom krizom.
English: Three patients presented a complete haematological response (CHR) and one patient experienced a partial haematological response (PHR).
Croatian: Tri bolesnika postigla su kompletni hematološki odgovor (CHR), a jedan bolesnik parcijalni hematološki odgovor (PHR).
English: Paediatric use: There is no experience in children with CML below 2 years of age and with Ph+ALL below 1 year of age (see section 5.1).
Croatian: Primjena u pedijatriji: Ne postoji iskustvo kod djece s KML-om mlađe od 2 godine i djece mlađe od 1 godine s Ph+ ALL-om (vidjeti dio 5.1).
English: Patients should be tested for HBV infection before initiating treatment with Imatinib Teva B.V.
Croatian: Bolesnike je potrebno testirati na infekciju HBV-om prije početka liječenja Imatinibom Teva B.V.
English: While you are taking Imatinib Teva B.V. your doctor will regularly check whether the medicine is working.
Croatian: Dok uzimate Imatinib Teva B.V., liječnik će redovito pratiti da li lijek djeluje.
English: The median time to progression in the overall population of 411 patients with relapsed/refractory Ph+ ALL ranged from 2.6 to 3.1 months, and median overall survival in the 401 evaluable patients ranged from 4.9 to 9 months.
Croatian: Medijan vremena do progresije u ukupnoj populaciji od 411 bolesnika s recidivirajućom ili refraktornom Ph+ ALL kretao se od 2,6 do 3,1 mjesec, a medijan ukupnog preživljenja kod 401 evaluiranog bolesnika kretao se od 4,9 do
English: Imatinib Teva B.V. can reduce the number of white blood cells, so you might get infections more easily.
Croatian: B.V. može smanjiti broj bijelih krvnih stanica, pa možete lakše dobiti infekciju.
English: In adults the dose should be reduced from 400 to 300 mg or from 600 to 400 mg, or from 800 mg to 600 mg, and in children from 340 to 260 mg/m2/day.
Croatian: Dozu u odraslih treba sniziti s 400 na 300 mg ili s 600 na 400 mg, ili s 800 mg na 600 mg, a u djece s 340 na 260 mg/m2/dan.
English: In clinical trials in CML, drug discontinuation for drug-related adverse reactions was observed in 2.4% of newly diagnosed patients, 4% of patients in late chronic phase after failure of interferon therapy, 4% of patients in accelerated phase after failure of interferon therapy and 5% of blast crisis patients after failure of interferon therapy.
Croatian: U kliničkim ispitivanjima KML-a ukidanje lijeka zbog nuspojava povezanih s njegovom primjenom zapaženo je u 2,4% novodijagnosticiranih bolesnika, 4% bolesnika u kasnoj kroničnoj fazi nakon neuspjeha terapije interferonom, 4% bolesnika u ubrzanoj fazi nakon neuspjeha terapije interferonom i 5% bolesnika u blastičnoj krizi nakon neuspjeha terapije interferonom.
English: When female rats were dosed 14 days prior to mating and through to gestational day 6, there was no effect on mating or on number of pregnant females.
Croatian: 14 dana prije parenja pa sve do 6. dana gestacije, nije bilo učinka na parenje ili na broj skotnih ženki.
English: An additional four HES patients were found to be FIP1L1-PDGFRα-positive in other 3 published reports.
Croatian: Dodatna četiri bolesnika s HES-om bila su pozitivna za FIP1L1-PDGFRα u ostala 3 objavljena slučaja.
English: • Muscle weakness and spasms with an abnormal heart rhythm (signs of changes in the amount of
Croatian: • Mišićna slabost i grčevi mišića s abnormalnim srčanim ritmom (znakovi promjena količine
English: C/C, n. 4, Poligono Industrial Malpica, 50016 Zaragoza
Croatian: 4, Poligono Industrial Malpica, 50016 Zaragoza
English: Total bilirubin: >1.5-3.0 ULN AST: any
Croatian: Ukupni bilirubin: >1,5-3,0 GGN AST: bilo koja vrijednost
English: • The adjuvant treatment of adult patients who are at significant risk of relapse following resection of Kit (CD117)-positive GIST.
Croatian: • Adjuvantno liječenje odraslih bolesnika s visokim rizikom od recidiva bolesti nakon resekcije Kit (CD117)-pozitivnog GIST-a.
English: Your doctor will discuss with you the possible risks of taking Imatinib Teva B.V. during pregnancy.
Croatian: Liječnik će Vam objasniti moguće rizike od uzimanja Imatiniba Teva B.V. tijekom trudnoće.
English: Lymphoid blast crisis: a limited number of patients were enrolled in phase I studies (n=10).
Croatian: Limfatična blastična kriza: u ispitivanjima faze I uključen je ograničeni broj bolesnika (n=10).
English: • Adult patients with Ph+ CML in blast crisis.
Croatian: • Odraslih bolesnika s Ph+ KML-om u blastičnoj krizi.
English: Overall hazard ratio (95% CI)*
Croatian: Ukupni omjer rizika (95% CI) *
English: In the study in patients with unresectable and/or metastatic GIST, grade 3 and 4 anaemia was reported in 5.4% and 0.7% of patients, respectively, and may have been related to gastrointestinal or intra-tumoural bleeding in at least some of these patients.
Croatian: U ispitivanju s bolesnicima s inoperabilnim i/ili metastazirajućim GIST-om, anemija 3. i 4. stupnja zabilježena je u 5,4% odnosno 0,7% bolesnika i mogla je biti povezana s gastrointestinalnim ili intratumorskim krvarenjem barem u nekih od tih bolesnika.
English: - If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby ask your doctor for advice before taking this medicine.
Croatian: Ako ste trudni ili dojite, mislite da biste mogli biti trudni ili planirate imati dijete, obratite se svom liječniku za savjet prije nego uzmete ovaj lijek.
English: The decreases in white blood cell (WBC) and neutrophil counts occurred mainly during the first six weeks of therapy, with values remaining relatively stable thereafter.
Croatian: Do smanjenja broja leukocita (Lkc) i broja neutrofila uglavnom je došlo tijekom prvih šest tjedana terapije, a vrijednosti su nakon toga ostale relativno
English: Teva Pharmaceuticals Polska Sp. z o.o.
Croatian: Teva Operations Poland Sp. z o.o. ul.
English: No specific dose recommendation is necessary in older people.
Croatian: Za starije osobe nije potrebna posebna preporuka doziranja.
English: In adult patients, Imatinib Teva B.V. is intended for use in the most advanced phase of the disease (blast crisis).
Croatian: U odraslih bolesnika, Imatinib Teva B.V. je namijenjen za liječenje najuznapredovanijih faza bolesti (blastična kriza).
English: Frequency categories are defined using the following convention: very common (≥1/10), common
Croatian: Kategorije učestalosti se definiraju kao: vrlo često (≥1/10), često
English: At the time of the original analysis, three of the four patients with detected PDGFR gene rearrangements developed haematological response (2 CHR and 1 PHR).
Croatian: U vrijeme početne analize, kod tri od četiri bolesnika s utvrđenom preuredbom gena za PDGFR razvio se hematološki odgovor (2 CHR i 1 PHR).
English: At one year the overall RFS was significantly better for imatinib (97.7%) vs. placebo (82.3%), (p<0.0001).
Croatian: Nakon jedne godine ukupno preživljenje bez recidiva bolesti bilo je značajno bolje za imatinib (97,7%) u odnosu na placebo (82,3%), (p<0,0001).
English: The comparison of AUC(0-24) on day 8 and day 1 at the 340 mg/m2/day dose level revealed a 1.7-fold drug accumulation after repeated once-daily dosing.
Croatian: Usporedba AUC(0-24) na dan 8 i dan 1 uz dozu od 340 mg/m2/dan otkrila je 1,7 puta veću akumulaciju lijeka nakon ponovljenog
English: Median time to response was 13 weeks (95% C.I.
Croatian: Medijan vremena do odgovora bio je 13 tjedana (95% CI 12-23).
English: Carriers of HBV who require treatment with Imatinib Teva B.V. should be closely monitored for signs and symptoms of active HBV infection throughout therapy and for several months following termination of therapy (see section 4.8).
Croatian: Nositelje virusa HBV kojima je potrebno liječenje Imatinibom Teva B.V. potrebno je pozorno nadzirati radi utvrđivanja eventualnih znakova i simptoma aktivne infekcije HBV-om tijekom terapije te nekoliko mjeseci nakon završetka terapije (vidjeti dio 4.8).
English: Therefore, caution should be recommended when driving a car
Croatian: Stoga se preporučuje oprez pri upravljanju vozilima ili radu sa strojevima.
English: Imatinib Teva B.V. may do the same to some other medicines.
Croatian: Imatinib Teva B.V. može to isto napraviti nekim drugim lijekovima.
English: There are no controlled trials in paediatric patients with c-Kit positive GIST.
Croatian: Nema kontroliranih ispitivanja u pedijatrijskih bolesnika s c-Kit pozitivnim GIST-om.
English: When needed, discontinuation of Imatinib Teva B.V. treatment may be considered.
Croatian: Ukoliko je potrebno, može se razmotriti prekid liječenja Imatinibom Teva B.V.
English: You should wash your hands immediately after opening the capsules.
Croatian: Operite ruke odmah nakon
English: In two clinical studies (study B2222 and an intergroup study S0033) the daily dose of imatinib was escalated to 800 mg in patients progressing at the lower daily doses of 400 mg or 600 mg.
Croatian: U dvije kliničke studije (studija B2222 i intergrupna studija S0033) dnevna doza imatiniba je povećana do 800 mg u bolesnika kod kojih je došlo do progresije pri nižim dnevnim dozama od 400
English: - If you are a woman who is pregnant or might get pregnant and are trying to open the capsules, you should handle the contents with caution in order to avoid skin-eye contact or inhalation.
Croatian: Ako ste trudni ili možete ostati trudni, a pokušavate otvoriti kapsule, morate pažljivo rukovati sa sadržajem te izbjegavati kontakt s kožom i očima ili inhaliranje.
English: • Severe headache, weakness or paralysis of limbs or face, difficulty speaking, sudden loss of consciousness (signs of nervous system problems such as bleeding or swelling in skull/brain).
Croatian: • teška glavobolja, slabost ili paraliza udova ili lica, otežan govor, iznenadni gubitak svijesti (znakovi problema živčanog sustava kao što su krvarenje ili oticanje u lubanji/mozgu).