FrancophonIA/ELRC3.0 huggingface dataset:
English: If it is almost time for the next dose, do not take or give the missed dose.
Croatian: Ako je ubrzo vrijeme za sljedeću dozu, nemojte uzeti/dati propuštenu dozu.
English: Always take the dose recommended by your doctor.
Croatian: Uvijek uzimajte dozu koju Vam je preporučio Vaš liječnik.
English: OTHER SPECIAL WARNING(S), IF NECESSARY
Croatian: DRUGA POSEBNA UPOZORENJA), AKO JE POTREBNO
English: Date of first authorisation: 18th September 2007 Date of latest renewal: 20 July 2012
Croatian: Datum posljednje obnove odobrenja: 20. srpnja 2012.
English: Talk to your doctor if this applies to you.
Croatian: Razgovarajte sa svojim liječnikom ako se to odnosi na Vas.
English: This helps your body to increase the CD4 cell count in your blood.
Croatian: Na taj način pomaže tijelu da poveća broj CD4 stanica u krvi.
English: Refer to section 4.5 for corresponding adult dosage.
Croatian: Vidjeti dio 4.5 za odgovarajuće doze za odrasle.
English: • tuberculosis (TB) or serious fungal infections.
Croatian: • tuberkulozu (TBC) ili ozbiljne gljivične infekcije.
English: No relevant difference between Caucasian, Asian and Black subjects has been observed.
Croatian: Nisu primijećene značajne razlike među ispitanicima bijelcima, Azijcima i crncima.
English: If you have a kidney problem, your doctor may alter your dose.
Croatian: Ako imate bubrežnih tegoba, liječnik će Vam možda promijeniti dozu.
English: The MOTIVATE studies were extended beyond 96 weeks, with an observational phase extended to 5 years in order to assess the long term safety of maraviroc.
Croatian: Ispitivanja MOTIVATE su produžena iza 96. tjedna, a uključivala su opservacijsku fazu produženu na 5 godina, kojoj je cilj bio ocijeniti dugoročnu sigurnost maraviroka.
English: • fever (high temperature).
Croatian: • vrućicu (visoku tjelesnu temperaturu)
English: This should be taken into consideration when treating infections such as active tuberculosis and invasive fungal infections.
Croatian: O tome treba voditi računa kod liječenja infekcija poput aktivne tuberkuloze ili invazivnih gljivičnih infekcija.
English: Therefore, dosing frequencies of longer than 24 hours in subjects with renal impairment may result in inadequate exposures between 24-48 hours.
Croatian: Stoga učestalost doziranja duža od 24 sata u ispitanika s oštećenjem bubrežne funkcije može rezultirati neadekvatnim ekspozicijama u razdoblju između 24-48 sati.
English: Further management should be as recommended by the national poisons centre, where available.
Croatian: Daljnje zbrinjavanje mora biti u skladu s preporukama državnog centra za trovanje, ako postoji.
English: Traditional IC50/IC90 fold-change was not a useful parameter to measure phenotypic resistance, as those values were sometimes unchanged despite significantly reduced sensitivity.
Croatian: Uobičajeni IC50/IC90 odnos promjena nije se pokazao kao dobra mjera određivanja fenotipske rezistencije, budući da su te vrijednosti ponekad ostale nepromijenjene usprkos značajno smanjenoj osjetljivosti.
English: Contact your doctor or the nearest hospital immediately.
Croatian: Odmah se obratite svom liječniku ili otiđite u najbližu bolnicu.
English: This dose adjustment has not been studied in HIV patients.
Croatian: Ova prilagodba doze nije istraživana kod bolesnika s HIV-om.
English: HIV infection is spread by sexual contact with someone who has the infection, or by transfer of infected blood (for example, by sharing injection needles).
Croatian: HIV infekcija se širi spolnim odnosom s nekime tko ima infekciju ili prijenosom zaražene krvi (primjerice, dijeljenjem igala za injekciju).
English: Alternative treatment options should be considered.
Croatian: Potrebno je razmotriti druge mogućnosti liječenja.
English: If you belong to this age group, discuss with your doctor if you can use CELSENTRI.
Croatian: Ako pripadate ovoj dobnoj skupini, razgovarajte sa svojim liječnikom o tome smijete li primjenjivati CELSENTRI.
English: Check with your doctor if you think this applies to you or your child.
Croatian: Provjerite sa svojim liječnikom ako mislite da se to odnosi na Vas ili Vaše dijete.
English: Alanine aminotransferase
Croatian: Alanin aminotransferaza
English: Pfizer Service Company, Hoge Wei 10, B 1930 Zaventem, Belgium
Croatian: Pfizer Service Company, Hoge Wei 10, B 1930 Zaventem, Belgija.
English: CELSENTRI has only been taken by limited numbers of people 65 years or older.
Croatian: CELSENTRI se primjenjivao samo kod malog broja osoba u dobi od 65 ili više godina.
English: In rats, there were no adverse effects on male or female fertility (see section 5.3).
Croatian: U štakora nije bilo štetnih učinaka na mušku ili žensku plodnost (vidjeti dio 5.3).
English: Other metabolites are products of mono-oxidation and are only minor components of plasma radioactivity.
Croatian: Ostali metaboliti nastaju monooksidacijom i predstavljaju samo mali dio radioaktivnosti plazme.
English: Remove the applicator from the adapter.
Croatian: Izvucite aplikator iz nastavka.
English: Only a limited number of people with serious heart or circulatory problems have taken CELSENTRI.
Croatian: Samo je ograničen broj ljudi s ozbiljnim tegobama sa srcem ili cirkulacijom uzimao lijek CELSENTRI.
English: When they start treatment, the immune system becomes stronger, so the body starts to fight infections.
Croatian: Kada te osobe započnu liječenje, njihov imunosni sustav jača, pa se tijelo počne boriti protiv infekcija.
English: The corresponding paediatric dose can then be obtained from Table 1 below.
Croatian: Odgovarajuća pedijatrijska doza može se zatim utvrditi iz Tablice 1 u nastavku.
English: If you accidentally take or give too much CELSENTRI:
Croatian: Ako slučajno uzmete ili date previše lijeka CELSENTRI:
English: (See also ‘Liver problems' in section 4).
Croatian: (Pogledajte i odlomak 'Jetrene tegobe' u dijelu 4.)
English: This will allow your doctor to prescribe the right dose of CELSENTRI.
Croatian: To će omogućiti liječniku da propiše točnu dozu lijeka CELSENTRI.
English: Approximately 20% of the radiolabel was recovered in the urine and 76% was recovered in the faeces over 168 hours.
Croatian: Približno 20% radioaktivnosti izmjereno je u urinu, a 76% u fecesu tijekom 168 sati.
English: Administration of activated charcoal may also be used to aid in removal of unabsorbed active substance.
Croatian: Primjena aktivnog ugljena također može pomoći uklanjanju neresorbirane aktivne tvari.
English: Primary pharmacological activity (CCR5 receptor affinity) was present in the monkey (100% receptor occupancy) and limited in the mouse, rat, rabbit and dog.
Croatian: Osnovna farmakološka aktivnost (afinitet za CCR5 receptore) bila je prisutna u majmuna (100%-tna zauzetost receptora), a ograničeno prisutna u miševa, štakora, kunića i pasa.
English: It is not known whether the ingredients in CELSENTRI can also pass into breast milk.
Croatian: Nije poznato mogu li sastojci lijeka CELSENTRI također prijeći u majčino mlijeko.
English: • headache, problems sleeping, depression
Croatian: • glavobolja, problemi sa spavanjem, depresija
English: Residual activity in vivo for viruses with MPI-values <95% has not been determined.
Croatian: Rezidualna aktivnost in vivo za viruse s MPI vrijednostima <95% još nije utvrđena.
English: If you take or give more CELSENTRI than you should
Croatian: Ako uzmete ili date više lijeka CELSENTRI nego što ste trebali
English: Data to support these doses are lacking.
Croatian: Nema dovoljno podataka koji bi poduprli ove doze
English: Changes in viral tropism occur over time in HIV-1 infected patients.
Croatian: Promjene tropizma virusa događaju se tijekom vremena kod bolesnika zaraženih s HIV-1.
English: Stevens-Johnson syndrome / Toxic epidermal necrolysis rare / not known
Croatian: Stevens-Johnsonov sindrom/toksična epidermalna nekroliza rijetko/nepoznato
English: If you are allergic to peanut or soya do not use this medicinal product.
Croatian: Ako ste alergični na kikiriki ili soju, ne smijete uzimati ovaj lijek.
English: Pull out applicator plunger (D) until the applicator contains the first part of the full dose.
Croatian: Izvlačite klip aplikatora (D) sve dok ne uvučete prvi dio cijele doze u aplikator.
English: The population was 52% female and 69% black, with mean age of 10 years (range: 2 years to 17 years).
Croatian: U populaciji je 52% ispitanika bilo ženskog spola, a 69% crne rase, dok je srednja vrijednost dobi iznosila 10 godina (raspon: 2 - 17 godina).
English: Maraviroc is primarily metabolized and eliminated by the liver.
Croatian: Maravirok se pretežno metabolizira i eliminira putem jetre.
English: If you (or your child) miss a dose of CELSENTRI, take or give the missed dose as soon as possible and then continue with the next dose at its regular time.
Croatian: Ako Vi (ili Vaše dijete) propustite dozu lijeka CELSENTRI, uzmite ili dajte propuštenu dozu što prije, a zatim nastavite uzimati lijek prema uobičajenom rasporedu.
English: Read the information ‘Other possible side effects of combination therapy for HIV' in Section 4 of this leaflet.
Croatian: Pročitajte informacije navedene u odlomku 'Druge moguće nuspojave kombinirane terapije za HIV' u dijelu 4. ove upute.
English: CCR5 antagonists could potentially impair the immune response to certain infections.
Croatian: Antagonisti CCR5 mogu utjecati na slabljenje imunološkog odgovora na neke infekcije.
English: • feeling weak or lack of energy, anaemia (seen in blood test result)
Croatian: • osjećaj slabosti ili nedostatka energije, anemija (vidljivo u nalazima krvnih pretraga)
English: 2 What you need to know before you take CELSENTRI Do not take CELSENTRI:
Croatian: Što morate znati prije nego počnete uzimati CELSENTRI Nemojte uzimati CELSENTRI:
English: People with advanced HIV infection (AIDS) have weak immune systems, and are more likely to develop serious infections (opportunistic infections).
Croatian: Osobe s uznapredovalom HIV infekcijom (AIDS) imaju oslabljen imunosni sustav, pa su sklonije razvoju ozbiljnih infekcija (oportunističke infekcije).
English: No relevant differences in pharmacokinetics have been observed.
Croatian: Nisu primijećene značajnije razlike u farmakokinetici.
English: Dialysis had a minimal effect on exposure in subjects with ESRD.
Croatian: Dijaliza je imala minimalni učinak na ekspoziciju u ispitanika s ESRD.
English: Maraviroc should be used during pregnancy only if the expected benefit justifies the potential risk to the foetus.
Croatian: Maravirok se smije primjenjivati u trudnoći samo ako očekivana korist od njegove primjene nadilazi potencijalni rizik za plod.
English: The most significant circulating metabolite in humans is a secondary amine (approximately 22% radioactivity) formed by N-dealkylation.
Croatian: Najznačajniji metabolit u cirkulaciji čovjeka je sekundarni amin (približno 22% radioaktivnosti) koji nastaje N-dealkilacijom.
English: The effect of maraviroc on human pregnancy is unknown.
Croatian: Učinak maraviroka na trudnoću u ljudi nije poznat.
English: CELSENTRI could potentially increase your risk of developing infections.
Croatian: CELSENTRI bi teoretski mogao povećati rizik od nastanka infekcija.
English: In mice and human beings that lack CCR5 receptors through genetic deletion, no significant adverse consequences have been reported.
Croatian: U miševa i ljudi, koji nemaju CCR5 receptore zbog genskog nedostatka, nisu primijećene značajnije neželjene posljedice.
English: Some medicines may change the amount of CELSENTRI in the body when they are taken at the same time as CELSENTRI.
Croatian: Neki lijekovi mogu utjecati na razinu lijeka CELSENTRI u tijelu ako se uzimaju istodobno kad i CELSENTRI.
English: All subjects (n = 103) received maraviroc twice daily and OBT.
Croatian: Svi ispitanici (n = 103) primali su maravirok dva puta na dan i OBT.
English: No clinically significant interaction seen.
Croatian: Nisu primijećene klinički značajne interakcije.
English: Maraviroc is bound (approximately 76%) to human plasma proteins, and shows moderate affinity for albumin and alpha-1 acid glycoprotein.
Croatian: Maravirok je vezan (približno 76%) na humane proteine plazme i pritom pokazuje umjereni afinitet za albumine i kiseli alfa-1 glikoprotein.
English: Rifabutin + PI
Croatian: Rifabutin + IP
English: Hence, the relevance of these mutations to maraviroc susceptibility in other viruses is not known.
Croatian: Stoga nije poznata važnost ovih mutacija za osjetljivost drugih virusa na maravirok.
English: It is recommended that mothers infected by HIV do not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Croatian: Preporučuje se da majke zaražene HIV-om ni u kom slučaju ne doje svoju djecu kako bi se izbjegao prijenos HIV-a.
English: If you get any symptoms of infection or if you notice any of the symptoms above:
Croatian: Ako primijetite bilo koji simptom infekcije ili bilo koji od gore navedenih simptoma:
English: Keep it safely 2.
Croatian: Odložite ga na sigurno.
English: You need to know about important signs and symptoms to look out for while you're taking CELSENTRI.
Croatian: Morate se upoznati s važnim znakovima i simptomima na koje trebate pripaziti tijekom liječenja lijekom CELSENTRI.
English: Slowly push the plunger in, allowing time to swallow.
Croatian: Polako pritišćite klip, ostavljajući dovoljno vremena za gutanje.
English: The antiviral activity of maraviroc against HIV-2 has not been evaluated.
Croatian: Antivirusna aktivnost maraviroka protiv HIV-2 nije ispitivana.
English: Pharmacotherapeutic group: Antivirals for systemic use, other antivirals, ATC code: J05AX09
Croatian: Farmakoterapijska skupina: Antivirotici za sustavnu primjenu, ostali antivirotici; ATK oznaka: J05AX09.
English: Caution should be exercised when treating these patients.
Croatian: Treba biti posebno oprezan u liječenju tih bolesnika.
English: Do not take or give a double dose to make up for a forgotten dose.
Croatian: Nemojte uzeti/dati dvostruku dozu kako biste nadoknadili propuštenu.
English: Rifabutin is considered to be a weaker inducer than rifampicin.
Croatian: Rifabutin se smatra slabijim induktorom od rifampicina.
English: These may affect 1 to 10 in 100 people:
Croatian: Mogu se javiti u 1 do 10 na 100 osoba:
English: Other possible side effects of combination therapy for HIV
Croatian: Ostale moguće nuspojave kombinirane terapije za HIV
English: At higher exposure of maraviroc a potential inhibition of CYP2D6 cannot be excluded.
Croatian: Pri višim koncentracijama maraviroka ne može se isključiti potencijalna inhibicija CYP2D6.
English: Your doctor will advise you whether it is better to take CELSENTRI oral solution, if you (or your child) are unable to swallow tablets.
Croatian: Liječnik će Vam reći je li bolje da uzimate CELSENTRI oralnu otopinu ako Vi (ili Vaše dijete) ne možete progutati tablete.
English: However, maraviroc does not significantly affect the pharmacokinetics of digoxin in vivo.
Croatian: Međutim, maravirok ne utječe značajno na farmakokinetiku digoksina in vivo.
English: For details please refer to the pharmacology section of the CELSENTRI European Public Assessment Report (EPAR) on the European Medicines Agency (EMA) website.
Croatian: Za detalje molimo pogledati farmakološki dio Europskog javnog izvješća o ocjeni dokumentacije (EPAR) za lijek CELSENTRI na internetskim stranicama Europske agencije za lijekove (EMA)
English: • low blood pressure, including dizziness when you stand up or sit up quickly, or if you are taking any medicines to lower blood pressure.
Croatian: • nizak krvni tlak, uključujući omaglicu pri naglom ustajanju ili sjedanju, ili uzimanje bilo kakvih lijekova za snižavanje krvnog tlaka.
English: These medicines are all called anti-HIV medicines or antiretrovirals.
Croatian: Ti se lijekovi nazivaju lijekovima protiv HIV-a ili antiretroviroticima.
English: Dispose of any unused oral solution 60 days after first opening the bottle.
Croatian: Bacite svu neupotrijebljenu oralnu otopinu 60 dana nakon prvog otvaranja boce.
English: CELSENTRI must be taken in combination with other medicines which are also used to treat the HIV infection.
Croatian: CELSENTRI se mora primjenjivati u kombinaciji s drugim lijekovima koji se također koriste za liječenje HIV infekcije.
English: Maraviroc is the major circulating component (approximately 42% radioactivity) following a single oral dose of 300 mg.
Croatian: Maravirok predstavlja najveću komponentu lijeka u cirkulaciji (približno 42% radioaktivnosti) nakon primjene jednokratne oralne doze od 300 mg.
English: Contact a doctor immediately if you get these symptoms.
Croatian: Odmah se obratite liječniku ako primijetite ove simptome.
English: Treatment of overdose should consist of general supportive measures including keeping the patient in a supine position, careful assessment of patient vital signs, blood pressure and ECG.
Croatian: Predoziranje se liječi općim potpornim mjerama, koje uključuju stavljanje bolesnika u ležeći položaj, pažljivo praćenje vitalnih znakova, mjerenje krvnog tlaka i EKG.
English: How to take CELSENTRI
Croatian: Kako uzimati CELSENTRI
English: The recommended dose of CELSENTRI differs depending on interactions with concomitant antiretroviral therapy and other medicinal products.
Croatian: Preporučena doza lijeka CELSENTRI razlikuje se ovisno o interakcijama s istodobno primijenjenim antiretrovirusnim i drugim lijekovima.
English: Symptoms of infection and inflammation may develop, caused by either:
Croatian: Mogu se razviti simptomi infekcije i upale uzrokovani:
English: For combination with etravirine + PI, see below.
Croatian: Za kombinaciju s etravirinom + IP vidjeti dolje.
English: Oral solution Pfizer Service Company Hoge Wei 10
Croatian: Oralna otopina Pfizer Service Company Hoge Wei 10
English: Breast-feeding Women who are HIV-positive must not breast-feed, because HIV infection can be passed on to the baby in breast milk.
Croatian: Žene zaražene HIV-om ne smiju dojiti jer se HIV infekcija može prenijeti na dijete kroz majčino mlijeko.
English: Taking your medicines at the right time every day is important as it makes sure the HIV infection does not increase in your body.
Croatian: Uzimanje lijeka svakoga dana u pravo vrijeme je važno jer sprječava pogoršanje HIV infekcije.
English: The safety and efficacy of maraviroc have not been specifically studied in patients with significant underlying liver disorders.
Croatian: Sigurnost i djelotvornost maraviroka nije posebno ispitivana kod bolesnika sa značajnijim postojećim poremećajima jetre.
English: Maraviroc inhibits P-glycoprotein in vitro (IC50 is 183 μM).
Croatian: Maravirok inhibira P-glikoprotein in vitro (IC50 iznosi 183 µM).
English: These findings are considered of low human relevance.
Croatian: Smatra se da ovi nalazi imaju nizak značaj za primjenu kod ljudi.
English: Prior to deciding the dose of CELSENTRI by weight, please refer to Table 2 in section 4.5 to carefully determine the corresponding adult dose.
Croatian: Prije nego što odredite dozu lijeka CELSENTRI na temelju tjelesne težine, pogledajte Tablicu 2 u dijelu 4.5 i pažljivo odredite odgovarajuću dozu za odrasle.
English: Data to support these doses are lacking and CELSENTRI is not recommended in children taking concomitant interacting medicinal products that in adults would require a 600 mg twice daily dose.
Croatian: Nema dovoljno podataka koji bi poduprli ove doze, pa se primjena lijeka CELSENTRI ne preporučuje u djece koja istodobno uzimaju lijekove koji bi u odraslih zahtijevali primjenu doze od 600 mg dva puta na dan.
English: How to store CELSENTRI Contents of the pack and other information
Croatian: Kako čuvati CELSENTRI 6. Sadržaj pakiranja i druge informacije
English: • drowsiness and confusion
Croatian: • omamljenost i smetenost
English: Contains soya lecithin: see leaflet for further information.
Croatian: 3. POPIS POMOĆNIH TVARI Sadrži sojin lecitin: vidjeti uputu o lijeku za dodatne informacije.
English: Before taking this medicine, make sure that your doctor knows if you (or your child) have or in the past had any of the following:
Croatian: Prije uzimanja ovog lijeka obavezno recite svome liječniku ako Vi (ili Vaše dijete) imate ili ste u prošlosti imali nešto od sljedećega:
English: • yellowing of skin or eyes
Croatian: • žutilo kože ili očiju
English: CELSENTRI contains a medicine called maraviroc.
Croatian: CELSENTRI sadrži lijek koji se zove maravirok.
English: Etravirine is only approved for use with boosted protease inhibitors.
Croatian: Etravirin je odobren samo za primjenu s pojačanim inhibitorima proteaze.
English: Do not drive, cycle, or operate tools or machines unless you are sure you're not affected.
Croatian: Nemojte upravljati vozilima, voziti bicikl ni raditi s alatima ili strojevima ako niste sigurni da lijek tako ne djeluje na Vas.
English: Overall, the safety profile in paediatric patients was similar to that observed in adult clinical studies.
Croatian: Sveukupno je sigurnosni profil u pedijatrijskih bolesnika bio sličan onom opaženom u kliničkim ispitivanjima provedenima u odraslih.
English: What CELSENTRI looks like and contents of the pack
Croatian: Kako CELSENTRI izgleda i sadržaj pakiranja
English: These adverse reactions were common (≥ 1/100 to < 1/10).
Croatian: Ove nuspojave su bile česte (1/100 do  1/10).
English: Frequencies are defined as very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥1/1000 to <1/100), rare (≥1/10,000 to <1/1000) , or not known (cannot be estimated from the available data).
Croatian: Učestalost je definirana kategorijama vrlo često (1/10), često (1/100 do 1/10), manje često (1/1000 do 1/100), rijetko (1/10 000 do 1/1000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: A randomised, double-blinded study (MERIT), explored maraviroc versus efavirenz, both in combination with zidovudine/lamivudine (n=721, 1:1).
Croatian: Randomizirano, dvostruko slijepo ispitivanje (MERIT) ocjenjivalo je maravirok u usporedbi s efavirenzom, oboje u kombinaciji sa zidovudinom/lamivudinom (n=721, 1:1).
English: CELSENTRI works by blocking a receptor called CCR5 which HIV uses to enter and infect your blood cells.
Croatian: CELSENTRI djeluje tako da blokira receptor CCR5, koji HIV koristi kako bi ušao u krvne stanice i zarazio ih.
English: • rash (see also ‘Serious allergic or skin reactions' earlier in section 4)
Croatian: • osip (pogledajte i odlomak 'Ozbiljne alergijske ili kožne reakcije' prethodno u dijelu 4.)
English: Some people taking medicines for HIV infection develop other conditions, which can be serious.
Croatian: U nekih osoba koje uzimaju lijekove za liječenje infekcije HIV-om mogu se razviti i neka druge bolesti, koje mogu biti ozbiljne.
English: One subject in each treatment arm met the primary endpoint by Week 48 (at Week 8 for placebo and Week 36 for the maraviroc arm).
Croatian: Po jedan ispitanik u svakoj liječenoj skupini postigao je primarni cilj do 48. tjedna (u 8. tjednu u placebo skupini i u 36. tjednu u maravirok skupini).
English: Studies with the tablets demonstrated a reduced foodeffect at higher doses.
Croatian: Ispitivanja s tabletama pokazala su smanjen utjecaj hrane pri većim dozama.
English: Cases of syncope caused by postural hypotension have been reported.
Croatian: Prijavljeni su slučajevi sinkope izazvane posturalnom hipotenzijom.
English:  Tell your doctor.
Croatian: Obavijestite svog liječnika.
English: Table 2: Interactions and adulta dose recommendations with other medicinal products
Croatian: Tablica 2: Interakcije i preporuke za doziranje u odrasliha kod primjene s drugim lijekovima
English: Maraviroc is not recommended to be used in treatment-naïve patients based on the results of a clinical study in this population (see section 5.1).
Croatian: Maravirok se ne preporučuje bolesnicima koji nisu prethodno liječeni, temeljem rezultata kliničke studije provedene na toj populaciji (vidjeti dio 5.1).
English: After 48 weeks of treatment, maraviroc did not reach non-inferiority to efavirenz for the endpoint of HIV-1 RNA < 50 copies/mL (65.3 vs. 69.3 % respectively, lower confidence bound -11.9%).
Croatian: Nakon 48 tjedana liječenja, maravirok nije postigao ne-inferiornost u odnosu na efavirenz za mjeru ishoda HIV-1 RNA <50 kopija/ml (65,3 prema 69,3%, donja granica pouzdanosti -11,9%).