FrancophonIA/ELRC3.0 huggingface dataset:
English: • serious infections of the skin or deeper layers under the skin, especially if you had holes in the gut wall or problems with wound healing,
Danish: • alvorlige infektioner i huden eller underliggende lag, især hvis du har haft huller i tarmvæggen eller problemer med sårheling
English: Progression-Free Survival Median (months)
Danish: Progressionfri overlevelse Median (måneder)
English: Sepsis, Abscessb,d,
Danish: Abscesa,b,d
English: In study BO20924 of Avastin with current standard of care in rhabdomyosarcoma and nonrhabdomyosarcoma soft tissue sarcoma, the safety profile of Avastin treated children was comparable with that observed in adults treated with Avastin.
Danish: I studie BO20924 hvor Avastin var givet sammen med standardbehandlingen af metastatisk rabdomyosarkom og ikke-rabdomyosarkom bløddelssarkom var sikkerhedsprofilen hos de Avastinbehandlede børn sammenlignelig med den som var observeret hos Avastinbehandlede voksne.
English: Avastin is administered in addition to platinum-based chemotherapy for up to 6 cycles of treatment followed by Avastin as a single agent until disease progression.
Danish: Avastin administreres sammen med platinbaseret kemoterapi i op til 6 behandlingsserier, efterfulgt af behandling med Avastin som monoterapi indtil sygdomsprogression.
English: The majority of patients in both arms had an ECOG Performance Status (PS) of 0 (CT: 56.4% vs. CT + BV: 61.2%).
Danish: Størstedelen af patienter i begge arme have ECOG-performancestatus på 0 (kemoterapi: 56,4 % versus kemoterapi + bevacizumab: 61,2 %).
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Danish: ● Overfølsomhed over for det aktive stof eller et eller flere af indholdsstofferne anført i pkt.
English: Carboplatin/ Paclitaxel + Avastin 15 mg/kg q 3 weeks
Danish: Arm 2 Carboplatin/ Paclitaxel + Avastin 15 mg/kg hver 3. uge
English: How to use Avastin
Danish: Sådan skal du bruge Avastin
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 100 mg/4 ml
Danish: INDHOLD ANGIVET SOM VÆGT, VOLUMEN ELLER ANTAL DOSER 100 mg/4 ml
English: Table 23 Efficacy Results from Study MO22224
Danish: Tabel 23 Effektresultater fra Studie MO22224 Primært endepunkt
English: Bevacizumab in combination with capecitabine is indicated for first-line treatment of adult patients with metastatic breast cancer in whom treatment with other chemotherapy options including taxanes or anthracyclines is not considered appropriate.
Danish: Bevacizumab er, i kombination med capecitabin, indiceret til 1.-linjebehandling af voksne patienter med metastatisk brystkræft, for hvem anden kemoterapi inklusive taxaner eller antracykliner ikke betragtes som værende hensigtsmæssig.
English: Combination with platinum- or taxane-based therapies (see sections 4.4 and 4.8) Increased rates of severe neutropenia, febrile neutropenia, or infection with or without severe neutropenia (including some fatalities) have been observed mainly in patients treated with platinumor taxane-based therapies in the treatment of NSCLC and mBC.
Danish: 4.4 og 4.8) Øget hyppighed af alvorlig neutropeni, febril neutropeni eller infektion med eller uden alvorlig neutropeni (herunder nogle dødsfald) er hovedsagelig blevet observeret hos patienter behandlet med platin- eller taxanbaserede terapier i behandlingen af NSCLC og mBC.
English: Grade 4 proteinuria (nephrotic syndrome) was seen in up to 1.4% of patients treated with Avastin.
Danish: Grad 4 proteinuri (nefrotisk syndrom) blev set hos op til 1,4% af de patienter, som blev behandlet med Avastin.
English: • muscle and joint pain, muscular weakness,
Danish: • muskel- og ledsmerter, muskelsvaghed,
English: Prior radiation is a major risk factor for the development of GI-vaginal fistulae and all patients with GIvaginal fistulae had a history of prior radiation.
Danish: Tidligere strålebehandling er en væsentlig risikofaktor for udvikling af gastrointestinale-vaginale fistler, og alle patienter, som fik gastrointestinale-vaginale fistler, havde tidligere fået strålebehandling.
English: • infections of the skin or deeper layers under the skin,
Danish: • infektion i huden eller i de dybereliggende lag under huden,
English: Bevacizumab in combination with fluoropyrimidine-based chemotherapy is indicated for treatment of adult patients with metastatic carcinoma of the colon or rectum.
Danish: Bevacizumab er, i kombination med kemoterapi baseret på fluoropyrimidin, indiceret til behandling af voksne patienter med metastatisk karcinom i colon eller rectum.
English: Of the 452 patients randomized at baseline, the majority of patients were white (80.0% in the Chemo alone group and 75.3% in the Chemo+Avastin group), had squamous cell carcinoma (67.1% in the Chemo alone group and 69.6% in the Chemo+Avastin group), had persistent/recurrent disease (83.6% in the Chemo alone group and 82.8% in the Chemo+Avastin group), had 1-2 metastatic sites (72.0% in the Chemo alone group and 76.2% in the Chemo+Avastin group), had lymph node involvement (50.2% in the Chemo alone group and 56.4% in the Chemo+Avastin group), and had a platinum free interval ≥ 6 months (72.5% in the Chemo alone group and 64.4% in the Chemo+Avastin group).
Danish: Af de 452 patienter randomiseret ved baseline var størstedelen kaukasiere (80,0 % i kemoterapigruppen og 75,3 % i kemoterapi+Avastingruppen), havde planocellulært karcinom (67,1 % i kemoterapigruppen og 69,6 % i kemoterapi+Avastingruppen), havde vedvarende/recidiverende sygdom (83,6 % i kemoterapigruppen og 82,8 % i kemoterapi+Avastingruppen), havde 1-2 metastatiske områder (72,0 % i kemoterapigruppen og 76,2 % i kemoterapi+Avastingruppen), havde lymfeknude-involvering (50,2 % i kemoterapigruppen og 56,4 % i kemoterapi+Avastingruppen) og havde en platin-fri periode på ≥ 6 måneder (72,5 % i kemoterapigruppen og 64,4 % i kemoterapi+Avastingruppen).
English: Exfoliative dermatitis, Dry skin, Skin discoloration
Danish: Eksfoliativ dermatitis Tør hud Misfarvet hud
English: The safety and efficacy of Avastin in the treatment of recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer was studied in three phase III trials (AVF4095g , MO22224 and GOG-0213) with different patient populations and chemotherapy regimens.
Danish: Avastins sikkerhed og virkning ved behandling af recidiverende epitelial ovariecancer, tubacancer og primær peritonealcancer blev undersøgt i tre fase III-studier (AVF4095g, MO22224 og GOG-0213) hos forskellige patientpopulationer og med forskellige kemoterapiregimer.
English: Patients with histologically confirmed mCRC and disease progression were randomised 1:1 within 3 months after discontinuation of bevacizumab first-line therapy to receive fluoropyrimidine/oxaliplatinor fluoropyrimidine/irinotecan-based chemotherapy (chemotherapy switched depending on first-line chemotherapy) with or without bevacizumab.
Danish: Patienter med histologisk bekræftet metastatisk kolorektalkræft og sygdomsprogression blev randomiseret 1:1 indenfor 3 måneder efter seponering af 1.linje bevacizumab-behandling og fik fluoropyrimidin/oxaliplatin- eller fluoropyrimidin/irinotecan-baseret kemoterapi (kemoterapi ændret afhængigt af 1.linje-kemoterapi) med eller uden bevacizumab.
English: • Gastrointestinal perforations (see section 4.4).
Danish: ● Gastrointestinale perforationer (se pkt.
English: If this happens you should talk to your doctor, pharmacist or nurse immediately.
Danish: Hvis det sker, skal du straks tale med din læge, apotekspersonale eller sundhedspersonale herom.
English: Grade 4 proteinuria (nephrotic syndrome) was seen in up to 1.4% of treated patients.
Danish: Grad 4 proteinuri (nefrotisk syndrom) blev set hos op til 1,4 % af de behandlede patienter.
English: Cases of non-mandibular osteonecrosis have been observed in Avastin treated paediatric patients (see section 4.8, Paediatric population).
Danish: Tilfælde af ikke-mandibulær osteonekrose er blevet observeret hos pædiatriske patienter behandlet med Avastin (se afsnittet ”pædiatrisk population” ovenfor i dette pkt.
English: INFORMATION IN BRAILLE Justification for not including Braille accepted
Danish: INFORMATION I BRAILLESKRIFT Fritaget for krav om blindeskrift
English: Patients who had received prior therapy with bevacizumab or prior systemic anticancer therapy for ovarian cancer (e.g. chemotherapy, monoclonal antibody therapy, tyrosine kinase inhibitor therapy, or hormonal therapy) or previous radiotherapy to the abdomen or pelvis were excluded from the study.
Danish: Patienter, som tidligere var behandlet med bevacizumab eller tidligere havde fået systemisk anticancerbehandling for ovariecancer (f.eks. kemoterapi, behandling med monoklonale antistoffer, behandling med tyrosinkinasehæmmer eller hormonbehandling), eller som tidligere havde fået strålebehandling af abdomen eller bækken, blev ekskluderet fra studiet.
English: Peripheral sensory neuropathy a
Danish: Perifer sensorisk neuropatia
English: Patients who have experienced a venous thromboembolic reaction may be at higher risk for a recurrence if they receive Avastin in combination with chemotherapy versus chemotherapy alone.
Danish: Patienter, som tidligere har oplevet en venøs tromboembolisk bivirkninger, kan have en højere risiko for fornyet hændelse, hvis de får Avastin i kombination med kemoterapi, end hvis de får kemoterapi alene.
English: For the posology and method of administration of erlotinib, please refer to the full erlotinib prescribing information.
Danish: Se produktresuméet for erlotinib for information vedrørende dosering og administration af erlotinib.
English: ● It is possible that Avastin can cause hypersensitivity and/or infusion reactions (reactions related to your injection of the medicine).
Danish: • Det er muligt, at Avastin kan forårsage allergiske og/eller infusionsrelaterede reaktioner.
English: • bleeding from the lower part of the large bowel,
Danish: • blødning fra den nedre del af tyktarmen
English: Hypertension was generally adequately controlled with oral anti-hypertensives such as angiotensin-converting enzyme inhibitors, diuretics and calcium-channel blockers.
Danish: Hypertension blev generelt adækvat behandlet med orale antihypertensiva som f.eks. ACE-hæmmere, diuretika og calciumantagonister.
English: • fever,
Danish: • feber,
English: The overall incidence of NCI-CTC Grade 3 and 4 hypertension in patients receiving Avastin ranged from 0.4% to 17.9%.
Danish: Den totale hyppighed af NCI-CTC grad 3 og 4 hypertension blev set hos mellem 0,4 % og 17,9 % af patienterne, som fik Avastin.
English: When Avastin is administered in combination with topotecan (given on days 1-5, every 3 weeks), the recommended dose of Avastin is 15 mg/kg of body weight given once every 3 weeks as an intravenous infusion.
Danish: Når Avastin administreres i kombination med topotecan (givet på dag 1-5 hver 3. uge), er den anbefalede Avastindosis 15 mg/kg kropsvægt en gang hver 3. uge som intravenøs infusion.
English: • hole in the gall bladder (symptoms and signs may include abdominal pain, fever, and nausea/vomiting).
Danish: • hul i galdeblæren (symptomer kan være mavesmerter, feber og kvalme/opkastning),
English: Table 18 Efficacy results from study BO17707 (ICON7)
Danish: Effektresultater fra studie BO17707 (ICON7)
English: Secondary PFS analyses, based on ‘on-treatment'-based response assessments, confirmed the significantly superior clinical benefit for patients treated with Avastin (analyses shown in Table 7), consistent with the statistically significant benefit observed in the pooled analysis.
Danish: Sekundære PFS analyser, baseret på responsvurderinger fra ”on-treatment”populationen, bekræftede den signifikante, superiore, kliniske effekt for patienter, behandlet med Avastin (analyser vist i tabel 7).
English: PHARMACEUTICAL FORM AND CONTENTS Concentrate for solution for infusion 1 vial of 16 ml
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) Koncentrat til infusionsvæske, opløsning 1 hætteglas á 16 ml
English: For further information as to HER2 status, please refer to section 5.1.
Danish: 5.1 for yderligere oplysninger HER2-status.
English: No increase in the incidence of other reactions, including gastrointestinal perforation, wound healing complications, congestive heart failure, and haemorrhage was observed in elderly patients (> 65 years)
Danish: Der blev ikke set øget hyppighed af andre bivirkninger, inklusive gastrointestinal perforation, sårhelingskomplikationer, kongestiv hjerteinsufficiens og blødninger hos ældre patienter (> 65 år), som fik Avastin, sammenlignet med patienter under 65 år, som fik Avastin.
English: Results from the randomised phase III studies, PACCE and CAIRO-2, in patients with mCRC suggest that the use of anti-EGFR monoclonal antibodies panitumumab and cetuximab, respectively, in combination with bevacizumab plus chemotherapy, is associated with decreased PFS and/or OS, and with increased toxicity compared with bevacizumab plus chemotherapy alone.
Danish: Resultater fra de randomiserede fase III-studier, PACCE og CAIRO-2, hos patienter med metastisk karcinom i colon eller rectum tyder på, at anvendelse af anti-EGFR monoklonale antistoffer, henholdsvis panitumumab og cetuximab, i kombination med bevaxizumab og kemoterapi, er forbundet med nedsat progressionsfri overlevelse (PFS) og/eller samlet overlevelse (OS) samt øget toksicitet sammenlignet med bevacizumab og kemoterapi alene.
English: ● a blood clot in your arteries,
Danish: • en blodprop i arterierne,
English: Caution should be exercised when treating patients with clinically significant cardiovascular disease such as pre-existing coronary artery disease, or congestive heart failure with Avastin.
Danish: Der bør udvises forsigtighed, når patienter med klinisk signifikant hjertesygdom, såsom hjertekarsygdom eller kongestiv hjerteinsufficiens, behandles med Avastin.
English: Table 26 Overall survival results from study GOG-0240 by Trial Treatment Treatment
Danish: Tabel 26: Resultater for samlet overlevelse fra studie GOG-0240 med forsøgsbehandling
English: Relative to control arm. NR = not reached.
Danish: NR=ikke nået.
English: Addition of Avastin to RT/T did not demonstrate clinical benefit in study BO25041 in 60 evaluable children patients with newly diagnosed supratentorial or infratentorial cerebellar or peduncular highgrade glioma (HGG) (See section 4.2 for information on paediatric use).
Danish: Tilføjelse af Avastin til RT/T vidste ikke kliniske fordele i studie BO25041 hos 60 evaluerbare børn med nyligt diagnosticeret supratentorielt eller infratentorielt cerebellært eller pedunkulært høj-gradsgliom (se pkt.
English: • CT+BV Arm (chemotherapy plus bevacizumab):
Danish: • Kemoterapi+bevacizumab-armen:
English: • Median PFS increase 5.6 months, HR 0.421 (p < 0.0001, 95% CI 0.343; 0.516)
Danish: • Median PFS-øgning på 5,6 måneder, hazard ratio 0,421 (p < 0,0001, 95 % konfidensinterval 0,343-0,516)
English: The primary endpoints of the trial were objective response rate and progression-free survival.
Danish: Det primære endepunkt for studiet var objektiv responsrate og progressionsfri overlevelse.
English: • Haemorrhage, including pulmonary haemorrhage/haemoptysis, which is more common in non small cell lung cancer patients (see section 4.4).
Danish: ● Blødninger, inklusive pulmonal blødning/hæmoptyse, som er mere almindelig hos patienter med ikke-småcellet lungekræft (se pkt.
English: PFS subgroup analyses by disease stage and debulking status are summarised in Table 17.
Danish: PFS-undergruppeanalyse af sygdomsstadie og tumorreduktionsstatus er sammenfattet i tabel 17.
English: Progression-free survivalb Investigator Assessment
Danish: Progressionsfri overlevelseb Investigators vurdering
English: A third group of 33 patients received bolus 5-FU/FA + Avastin (10 mg/kg every 2 weeks).
Danish: En tredje gruppe på 33 patienter fik bolus 5-FU/FA + Avastin (10 mg/kg hver 2. uge).
English: Avastin will be administered in combination with chemotherapy treatment containing a fluoropyrimidine medicine.
Danish: Avastin vil blive givet i kombination med kemoterapibehandling, der indeholder fluoropyrimidin.
English: Primary analysis was performed with a data cut-off date of 12 December 2012 and is considered the final analysis
Danish: Primær-analyse blev udført ved data cut-off 12. december 2012 og betragtes som den endelige analyse Followup-analyse blev udført ved data cut-off 7. marts 2014
English: Grade 3-5 (NCI-CTCAE v.3) venous thromboembolic reactions have been reported in up to 7.8% of patients treated with chemotherapy plus bevacizumab compared with up to 4.9% in patients treated with chemotherapy alone (across indications, excluding persistent, recurrent, or metastatic cervical cancer).
Danish: Venøse tromboemboliske bivirkninger af grad 3-5 (NCI-CTCAE v. 3) sås hos op mod 7,8 % af patienter, behandlet med kemoterapi plus bevacizumab i forhold til op mod 4,9 % af patienter, som fik kemoterapi alene (på tværs af indikationer eksklusive persisterende, recidiverende eller metastatisk cervixcancer).
English: Study AVF3694g was a Phase III, multicentre, randomised, placebo-controlled trial designed to evaluate the efficacy and safety of Avastin in combination with chemotherapy compared to chemotherapy plus placebo as first-line treatment for patients with HER2-negative metastatic or locally recurrent breast cancer.
Danish: AVF3694g var et fase III, multicenter, randomiseret, placebokontrolleret studie designet til at evaluere effekten og sikkerheden af Avastin i kombination med kemoterapi sammenlignet med kemoterapi plus placebo som 1.-linjebehandling til patienter med HER-2 negativ metastatisk eller lokalt recidiverende brystkræft.
English: The safety and efficacy of Avastin in the treatment of patients with platinum-sensitive, recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, who have not received prior chemotherapy in the recurrent setting or prior bevacizumab treatment, was studied in a phase III randomised, double-blind, placebo-controlled trial (AVF4095g).
Danish: Avastins sikkerhed og virkning ved behandling af platinfølsom, recidiverende epitelial ovariecancer, tubacancer eller primær peritonealcancer hos patienter, som ikke tidligere havde fået kemoterapi for recidiverende sygdom eller bevacizumab-behandling, blev undersøgt i et fase III, randomiseret, dobbeltblindet, placebokontrolleret studie (AVF4095g).
English: Therapy should be withheld for elective surgery.
Danish: Behandlingen bør midlertidigt stoppes før elektiv kirurgi.
English: Investigator assessment
Danish: Investigator vurdering
English: In randomised clinical trials, age > 65 years was associated with an increased risk of developing arterial thromboembolic reactions, including cerebrovascular accidents (CVAs), transient ischaemic attacks (TIAs) and myocardial infarctions (MIs).
Danish: Randomiserede, kliniske studier viste at alder > 65 år var associeret med øget risiko for udvikling af arterielle tromboemboliske bivirkninger, inklusive cerebrovaskulære tilfælde, transitorisk cerebral iskæmi og myokardieinfarkt.
English: Roche Pharma AG Emil-Barrell-Str. 1, D-79639 Grenzach-Wyhlen Germany
Danish: Roche Pharma AG Emil-Barrell-Str. 1, D-79639 Grenzach-Wyhlen Tyskland
English: Anti-tumour activity was not observed in two earlier studies among a total of 30 children aged > 3 years old with relapsed or progressive high-grade glioma when treated with bevacizumab and irinotecan (CPT-11).
Danish: Høj-grads-gliomI to tidligere studier med i alt 30 børn over 3 år med recidiverende eller progredierende høj-grads-gliom blev der ikke observeret antitumor-aktivitet ved behandling med bevacizumab og irinotecan (CPT-11).
English: Congestive heart failureb,d, Supraventricular tachycardia
Danish: Kongestivt hjertesvigta,b Supraventrikulær takykardi
English: Dehydration Hyponatraemia
Danish: Dehydrering Hyponatriæmi
English: Hypersensitivity to Chinese Hamster Ovary (CHO) cell products or other recombinant human or humanised antibodies.
Danish: ● Overfølsomhed over for præparater fremstillet i ovarieceller (CHO) fra kinesisk hamster eller andre rekombinante eller humaniserede antistoffer.
English: The difference in ORR per independent central review was 18% (CI: 0.6%, 35.3%) between the two treatment arms in the few patients who had evaluable tumor at baseline and had a confirmed response prior to receiving any local therapy : 27/75 patients (36.0%, 95% CI: 25.2%, 47.9%) in the Chemo arm and 34/63 patients (54.0%, 95% CI: 40.9%, 66.6%) in the Bv + Chemo arm.
Danish: Ifølge en uafhængig evalueringskomité var forskellen i objektiv responsrate 18% (konfidensinterval: 0,6 % ; 35,3 %) mellem de to behandlingsarme blandt de få patienter, der havde evaluerbare tumor ved baseline samt en bekræftet respons ved tidligere lokal behandling: 27/75 patienter (36,0 %; 95% konfidensinterval: 25,2 %; 47,9 %) i kemoterapi-armen og 34/63 patienter (54,0 %; 95 % konfidensinterval: 40,9 %; 66,6 %) i kemoterapi+bevacizumab-armen.
English: These results demonstrate robustness of the primary analysis of PFS as shown in Table 18.
Danish: Disse resultater påviser robusthed af PFS-analysen vist i tabel 18.
English: Median OS (months) Hazard Ratio (95% CI) p-value All analyses presented in this table are stratified analyses.
Danish: Median OS (måneder) Hazard ratio (95 % konfidensinterval) p-værdi Alle analyser i tabellen er stratificerede.
English: Comparison Other Factor
Danish: Anden faktor
English: Avastin will be administered in combination with paclitaxel and cisplatin or, alternatively, paclitaxel and topotecan in patients who cannot receive platinum therapy.
Danish: Avastin bliver givet sammen med paclitaxel og cisplatin eller med paclitaxel og topotecan til patienter, som ikke kan få platin.
English: Avastin is also used for the treatment of adult patients with metastatic breast cancer.
Danish: Avastin anvendes også hos voksne til behandling af metastatisk brystkræft.
English: • dry skin, flaking and inflammation of the skin, change in skin colour,
Danish: • tør hud, afskalning og inflammation (betændelseslignende tilstand) i huden, misfarvning af huden,
English: Study JO25567 was a randomized, open-label, multi-center Phase II study conducted in Japan to evaluate the efficacy and safety of Avastin used in addition to erlotinib in patients with non-squamous NSCLC with EGFR activating mutations (exon 19 deletion or exon 21 L858R mutation) who had not received prior systemic therapy for Stage IIIB/IV or recurrent disease.
Danish: Studie JO25567 var et randomiseret, åbent fase II multicenterstudie, gennemført i Japan, for at vurdere effekten og sikkerheden af Avastin, som tillæg til erlotinib,, hos patienter med ikke-planocellulær NSCLC med EGFR-aktiverende mutationer (exon 19-deletion eller exon 21L858R-mutation), som ikke tidligere havde fået systemisk behandling af grad IIIB/IV- eller recidiverende sygdom.
English: The HR for PFS was 0.47 (95% CI: 0.35, 0.62) and 0.45 (95% CI: 0.31, 0.67) for the < 65 and ≥ 65 subgroups, respectively.
Danish: Hazard ratio for progressionsfri overlevelse var 0,47 (95 % konfidensinterval: 0,35; 0,62) og 0,45 (95 % konfidensinterval: 0,31; 0,67) for henholdsvis undergruppe < 65 år og ≥ 65 år .
English: Treatment with Avastin at 15 mg/kg every 3 weeks in combination with chemotherapy (carboplatin and paclitaxel) for 6 and up to 8 cycles, followed by Avastin until disease progression or unacceptable toxicity resulted, when data were derived from eCRF, in a clinically meaningful and statistically significant improvement in OS compared to treatment with carboplatin and paclitaxel alone.
Danish: Behandling med Avastin 15 mg/kg hver 3. uge i kombination med kemoterapi (carboplatin og paclitaxel) i 6 og op til 8 behandlingsserier, efterfulgt af Avastin monoterapi indtil sygdomsprogression eller uacceptabel toksicitet, resulterede i en klinisk betydningsfuld og statistisk signifikant forbedring i samlet overlevelse sammenlignet med behandling med carboplatin og paclitaxel alene, ved data udledt fra eCRF.
English: Avastin is also used for the treatment of adult patients with advanced non-small cell lung cancer.
Danish: Avastin bruges også hos voksne til behandling af fremskreden ikke-småcellet lungekræft.
English: Diluted medicinal product
Danish: Fortyndet lægemiddel
English: Pregnancy (see section 4.6).
Danish: ● Graviditet (se pkt.