FrancophonIA/ELRC3.0 huggingface dataset:
English: Histologically, mild local reactions with chronic inflammation of the connective tissue and some capsule formation and collagen deposition have been seen at 3 months after administration following simultaneous subcutaneous administration of up to 10 times the recommended dose.
Croatian: Histološki, radi se o blagoj lokalnoj reakciji s kroničnom upalom vezivnog tkiva i mjestimičnom inkapsulacijom te depozicijom kolagena, što se može zamijetiti 3 mjeseca nakon primjene do 10 puta veće doze.
English: TARGET SPECIES Dogs (male) and ferrets (male)
Croatian: Psi (mužjaci) i afrički tvorovi (mužjaci)
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Suprelorin 9.4 mg implant for dogs and ferrets.
Croatian: Suprelorin 9,4 mg implantat za pse i afričke tvorove.
English: The use of the veterinary medicinal product in pre-pubertal dogs has not been investigated.
Croatian: Primjena VMP kod pasa prije puberteta još nije ispitivana.
English: In dogs: Moderate swelling at the implant site was commonly observed for 14 days during safety/efficacy studies.
Croatian: Psi: Obično se na mjestu implantacije javi oteklina umjerenog intenziteta koja može potrajati 14 dana.
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Suprelorin 9.4 mg implant for dogs and ferrets
Croatian: Suprelorin 9,4 mg implantat za pse i afričke tvorove
English: No clinical adverse reactions other than those described in the section “Adverse reactions” have been observed following subcutaneous administration of up to 10 times the recommended dose.
Croatian: Nuspojave drugačije od onih opisanih u djelu „Nuspojave“ nisu primijećene niti nakon istovremenog apliciranja 10 puta veće doze.
English: STATEMENT OF ACTIVE AND OTHER SUBSTANCES Each implant contains Deslorelin (as deslorelin acetate) 4.7 mg
Croatian: Deslorelin (u obliku deslorelin acetata) 4,7 mg
English: In ferrets: Transient moderate swelling, pruritus and erythema at the implant site were commonly observed during clinical studies.
Croatian: Afrički tvor: Uobičajena pojava tijekom kliničkih ispitivanja bila je prolazna oteklina umjerenog intenziteta, svrbež i crvenilo na mjestu implantacije.
English: If loss of the first implant is suspected, then this can be confirmed by observing no reduction in testis size or plasma testosterone levels as both should reduce under correct implantation.
Croatian: Ukoliko je taj gubitak povezan sa prvom implantacijom, neće doći do smanjenja obujma mošnji ili koncentracije testosterona u plazmi, jer oba pokazatelja moraju biti smanjena kada se implantacija izvrši pravilno.
English: For the induction of temporary infertility in healthy, entire, sexually mature male dogs and ferrets.
Croatian: Za indukciju privremene neplodnosti u zdravih, potpuno spolno zrelih mužjaka pasa i afričkih tvorova.
English: 1ère Avenue - 2065 m - L..I.D. 06516 Carros
Croatian: 1ère avenue 2065 m L.I.D. 06516 Carros FRANCUSKA
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) Deslorelin (as deslorelin acetate)
Croatian: Svaki implantat sadržava: deslorelin (u obliku deslorelin acetata)
English: Ferrets: There is no information available in ferrets concerning overdose.
Croatian: Nema dostupnih informacija o predoziranju kod afričkih tvorova
English: If loss of the first implant is suspected, then this can be confirmed by observing no reduction in scrotal circumference or plasma testosterone levels after 6 weeks from the suspected date of loss, as both should reduce under correct implantation.
Croatian: Ukoliko je taj gubitak povezan s prvom implantacijom, neće doći do smanjenja obujma mošnji ili koncentracije testosterona u plazmi, 6 tjedana nakon dana na koji sumnjamo da je došlo do gubitka, jer oba pokazatelja moraju biti smanjena kada se implantacija izvrši pravilno.
English: One implant should be administered subcutaneously between the shoulder blades of the dog.
Croatian: VMP treba implantirati potkožno u nabor na hrptu između lopatica.
English: Dogs: No adverse reactions other than those described in section “Adverse effects” have been observed following subcutaneous administration of up to 6 times the recommended dose.
Croatian: Niti jedna nuspojava do onih koje su opisane u djelu „Nuspojave“ nije bila primijećena nakon subkutane aplikacije 6 puta veće doze.
English: If loss of the first implant is suspected, then this can be confirmed by observing no reduction in scrotal circumference or plasma testosterone levels after 8 weeks from the suspected date of loss, as both should reduce under correct implantation.
Croatian: Ukoliko je taj gubitak povezan sa prvom implantacijom, neće doći do smanjenja obujma mošnji ili koncentracije testosterona u plazmi poslije 8 tjedana od dana na koji sumnjamo da je došlo do gubitka, jer oba pokazatelja moraju biti smanjena kada se implantacija izvrši pravilno.
English: 1ère avenue 2065 m LID FR-06516 Carros Tel: +33-(0)4 92 08 73 00
Croatian: FR-06516 Carros Tel: +33-(0) 4 92 08 73 00
English: If loss of the implant is suspected following re-implantation after 6 months, then a progressive increase will be seen in scrotal circumference and/or plasma testosterone levels.
Croatian: Ukoliko se posumnja da je implantat izgubljen prilikom re-implantacije poslije 6 mjeseci, tada će doći do progresivnog porasta obujma mošnji i/ili koncentracije testosterona u plazmi.
English: If loss of the implant is suspected following re-implantation after 12 months, then a progressive increase will be seen in scrotal circumference and/or plasma testosterone levels.
Croatian: Ukoliko se posumnja da je implantat izgubljen prilikom re-implantacije poslije 12 mjeseci tada će doći do progresivnog porasta obujma mošnji i/ili koncentracije testosterona u plazmi.
English: TARGET SPECIES Dogs (male) and ferrets (male).
Croatian: Psi (mužjaci) i afrički tvor (mužjaci).
English: If loss of the implant is suspected following reimplantation, then a progressive increase will be seen in testis size and/or plasma testosterone levels.
Croatian: Ukoliko se posumnja da je implantat izgubljen prilikom re- implantacije će doći do progresivnog porasta obujma testisa i/ili razine koncentracije u plazmi.
English: Repeat administration every 12 months to maintain efficacy.
Croatian: Ponoviti aplikaciju svakih 12 mjeseci radi održavanja djelotvornosti.
English: Repeat administration every 6 months to maintain efficacy.
Croatian: Ponoviti aplikaciju svakih 6 mjeseci radi održavanja djelotvornosti.
English: 1ère avenue 2065 m - LID FR-06516 Carros Frakkland
Croatian: 1ère avenue 2065 m LID FR-06516 Carros Prantsusmaa
English: Annex A
Croatian: DODATAK II
English: Immediate packaging
Croatian: Način primjene Pakovanje
English: Fatal cases have also been reported.
Croatian: Prijavljeni su i smrtni slučajevi.
English: Some cases had a fatal outcome (see section 4.9).
Croatian: U nekim slučajevima došlo je do smrtnog ishoda (vidjeti dio 4.9).
English: Patients should not exceed the recommended dose and/or the recommended duration of treatment.
Croatian: Bolesnici ne smiju prekoračiti preporučenu dozu i/ili preporučeno trajanje liječenja.
English: Do not take this product for anything other than its intended use (see section 1) and never take more than the recommended amount (see section 3).
Croatian: Ovaj lijek se ne smije primjenjivati u druge svrhe osim one za koju je namijenjen (pogledajte dio 1) i nikada nemojte uzeti više od preporučene količine (pogledajte dio 3).
English: Adopted at the 6-9 March 2017 PRAC
Croatian: Usvojeno na sjednici PRAC-a 6. - 9. ožujka 2017.
English: If a child takes too much or shows any of the above symptoms, call a doctor immediately.
Croatian: Ako dijete uzme previše lijeka ili pokaže bilo koji od prethodno navedenih simptoma, odmah se obratite liječniku.
English: Children react more strongly to large amounts of <brand name> than adults.
Croatian: Djeca će imati snažniju reakciju na velike količine lijeka <naziv lijeka> od odraslih.
English: Nivolumab; pembrolizumab - Transplant rejection (EPITT no 18781)
Croatian: Nivolumab; pembrolizumab - odbacivanje transplantiranog organa (EPITT br. 18781)
English: Symptoms may include: increased heart rate, irregular heartbeat, changes to your heartbeat (these symptoms can have potentially serious, life-threatening consequences), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, or weak breathing.
Croatian: Simptomi mogu uključivati: povećanu brzinu srčanih otkucaja, nepravilne otkucaje srca, promjene otkucaja srca (ovi simptomi mogu imati potencijalno ozbiljne, za život opasne posljedice), ukočenost mišića, nekoordinirane pokrete, omamljenost, otežano mokrenje ili oslabljeno disanje.
English: Before you get KEYTRUDA, tell your doctor if you: - have liver damage or have had a liver transplant - have kidney damage or have had a kidney transplant - have a solid organ transplant
Croatian: Prije nego što primite lijek KEYTRUDA, recite svom liječniku ako: - imate oštećenje jetre ili Vam je jetra presađena - imate oštećenje bubrega ili Vam je bubreg presađen - imate presađen solidni organ (unutarnji organ čvrste građe)
English: Loperamide - Serious cardiac events with high doses of loperamide from abuse and misuse (EPITT no 18339)
Croatian: Loperamid - ozbiljni kardiološki događaji kod primjene velikih doza loperamida prilikom zlouporabe i nepravilne primjene (EPITT br. 18339)
English: Non-clinical in vitro and in vivo evaluation of loperamide indicates no significant cardiac electrophysiological effects within its therapeutically relevant concentration range and at significant multiples of this range (up to 47-fold).
Croatian: Neklinička in vitro i in vivo ocjena loperamida ne ukazuje na značajne učinke na elektrofiziologiju srca u rasponu terapijski relevantnih koncentracija kao ni pri značajnim višestrukim vrijednostima tog raspona (do 47 puta).
English: Serious heart problems (symptoms of which include fast or irregular heartbeat) have been reported in patients who have taken too much loperamide, the active ingredient in <brand name>.
Croatian: Ozbiljni problemi sa srcem (simptomi koji uključuju brze ili nepravilne otkucaje srca) prijavljeni su u bolesnika koji su uzeli previše loperamida, djelatne tvari lijeka <naziv lijeka>.
English: 2 - What you need to know before you take <brand name>
Croatian: 2 - Što morate znati prije nego počnete uzimati lijek <naziv lijeka>
English: However, at extremely high concentrations associated with overdoses (see section 4.4), loperamide has cardiac electrophysiological actions consisting of inhibition of potassium (hERG) and sodium currents, and arrhythmias.
Croatian: Međutim, pri iznimno visokim koncentracijama povezanima s predoziranjem (vidjeti dio 4.4), loperamid ima djelovanje na elektrofiziologiju srca koje se sastoji od inhibicije struja kalija (hERG) i natrija te aritmija.
English: 2 - What you need to know before you are given KEYTRUDA Warnings and precautions
Croatian: 2 - Što morate znati prije nego počnete primati lijek KEYTRUDA
English: In individuals who have ingested overdoses of loperamide HCl, cardiac events such as QT interval prolongation, torsades de pointes, other serious ventricular arrhythmias, cardiac arrest and syncope have been observed (see section 4.4).
Croatian: Kod pojedinaca koji su se predozirali loperamidkloridom, opaženi su kardiološki događaji kao što je produženi QT interval, torsades de pointes, druge ozbiljne ventrikularne aritmije, srčani zastoj i sinkopa (vidjeti dio 4.4).
English: Talk to your doctor before using OPDIVO as it may cause: Solid organ transplant rejection
Croatian: Obratite se svom liječniku prije nego primite OPDIVO jer on može uzrokovati: Odbacivanje presađenog solidnog organa (unutarnjeg organa čvrste građe)
English: 3 - If you take more <brand name> than you should If you have taken too many <brand name>, immediately contact a doctor or hospital for advice.
Croatian: Ako ste uzeli previše lijeka <naziv lijeka>, odmah se obratite liječniku za savjet ili otiđite u bolnicu.
English: Nivolumab monotherapy
Croatian: Monoterapija nivolumabom
English: Cardiac events including QT prolongation and torsades de pointes have been reported in association with overdose.
Croatian: Posebna upozorenja i mjere opreza pri uporabi Prijavljena je povezanost predoziranja i kardioloških događaja, uključujući produženi QT interval i torsades de pointes.
English: Nivolumab in combination with ipilimumab Frequency ‘not known': Solid organ transplant rejection
Croatian: Učestalost „nepoznato”: Odbacivanje transplantiranog solidnog organa Nivolumab u kombinaciji s ipilimumabom2 - Što morate znati prije nego počnete primati OPDIVO
English: Your doctor may need to change your dose and/or to take other precautions:
Croatian: Liječnik će Vam možda morati promijeniti dozu i/ili poduzeti druge mjere opreza:
English: Date of first authorisation: 19 January 2007 Date of latest renewal: 19 January 2012
Croatian: Datum posljednje obnove: 19. siječnja 2012.
English: Irbesartan Hydrochlorothiazide Zentiva should be taken at least one hour before or four hours after these medications;
Croatian: Irbesartan Hydrochlorothiazide Zentiva se mora uzeti najmanje jedan sat prije ili 4 sata poslije tih lijekova;
English: It is important that you continue to take Irbesartan Hydrochlorothiazide Zentiva until your doctor tells you otherwise.
Croatian: Važno je da kontinuirano uzimate Irbesartan Hydrochlorothiazide Zentiva sve dok Vam liječnik ne odredi drugačije.
English: Irbesartan Hydrochlorothiazide Zentiva should not be given to children and adolescents (under 18 years).
Croatian: Irbesartan Hydrochlorothiazide Zentiva se ne smije davati djeci i adolescentima (mlađima od 18 godina).
English: Other medicines and Irbesartan Hydrochlorothiazide Zentiva Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Croatian: Drugi lijekovi i Irbesartan Hydrochlorothiazide Zentiva Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: When necessary, Irbesartan Hydrochlorothiazide Zentiva may be administered with another antihypertensive medicinal product (see sections 4.3, 4.4, 4.5 and 5.1).
Croatian: Kada je potrebno, Irbesartan Hydrochlorothiazide Zentiva se može primjenjivati s drugim antihipertenzivnim lijekom (vidjeti dijelove 4.3, 4.4, 4.5 i 5.1).
English: Since Irbesartan Hydrochlorothiazide Zentiva contains hydrochlorothiazide, it is not recommended during the first trimester of pregnancy.
Croatian: Budući da Irbesartan Hydrochlorothiazide Zentiva sadrži hidroklorotiazid, ne preporučuje se tijekom prvog tromjesečja trudnoće.
English: Your doctor will normally advise you to stop taking Irbesartan Hydrochlorothiazide Zentiva before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Irbesartan Hydrochlorothiazide Zentiva.
Croatian: Vaš će Vam liječnik obično preporučiti da prestanete koristiti Irbesartan Hydrochlorothiazide Zentiva prije nego što zatrudnite ili čim saznate da ste trudni te će Vam savjetovati da uzmete neki drugi lijek umjesto lijeka Irbesartan Hydrochlorothiazide Zentiva.
English: If you forget to take Irbesartan Hydrochlorothiazide Zentiva If you accidentally miss a daily dose, just take the next dose as normal.
Croatian: Ako ste zaboravili uzeti Irbesartan Hydrochlorothiazide Zentiva Ako slučajno zaboravite uzeti dnevnu dozu, samo uzmite sljedeću dozu kao što to obično i činite.
English: Do not use this medicine after the expiry date which is stated on the carton and on the blister after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji ili blisteru iza oznake „EXP“.
English: If you get any of the above symptoms or get short of breath, stop taking Irbesartan Hydrochlorothiazide Zentiva and contact your doctor immediately.
Croatian: Ako dobijete neki od tih simptoma ili ako imate nedostatak zraka, prestanite uzimati Irbesartan Hydrochlorothiazide Zentiva i odmah se obratite svome liječniku.
English: See also information under the heading “Do not take Irbesartan Hydrochlorothiazide Zentiva”.
Croatian: Vidjeti također informacije pod naslovom „Nemojte uzimati Irbesartan Hydrochlorothiazide Zentiva“.
English: If Irbesartan Hydrochlorothiazide Zentiva is used during breast feeding, doses should be kept as low as possible.
Croatian: Ako se Irbesartan Hydrochlorothiazide Zentiva primjenjuje tijekom dojenja, njegove doze trebaju biti što je moguće niže.
English: While this is not documented with Irbesartan Hydrochlorothiazide Zentiva, a similar effect should be anticipated.
Croatian: Iako to nije dokumentirano za Irbesartan Hydrochlorothiazide Zentiva, može se očekivati sličan učinak.
English: In addition to the side effects listed above, chest pain, severe allergic reactions (anaphylactic shock) and decrease in te number of platelets (a blood cell essential for the clotting of the blood) have also been reported.
Croatian: Uz gore navedene nuspojave zabilježene su i bol u prsnom košu, teške alergijske reakcije (anafilaktički šok) i smanjenje broja krvnih pločica (krvna stanica nužna za zgrušavanje krvi).
English: Irbesartan Hydrochlorothiazide Zentiva is not recommended for use in children and adolescents because the safety and efficacy have not been established.
Croatian: Ne preporučuje se primjena lijeka Irbesartan Hydrochlorothiazide Zentiva u djece i adolescenata jer sigurnost i djelotvornost nisu utvrđene.
English: What Irbesartan Hydrochlorothiazide Zentiva is and what it is used for What you need to know before you take Irbesartan Hydrochlorothiazide Zentiva How to take Irbesartan Hydrochlorothiazide Zentiva Possible side effects
Croatian: Što je Irbesartan Hydrochlorothiazide Zentiva i za što se koristi Što morate znati prije nego počnete uzimati Irbesartan Hydrochlorothiazide Zentiva Kako uzimati Irbesartan Hydrochlorothiazide Zentiva Moguće nuspojave
English: Irbesartan Hydrochlorothiazide Zentiva is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.
Croatian: Irbesartan Hydrochlorothiazide Zentiva se ne preporučuje majkama koje doje, a Vaš liječnik može izabrati drugu terapiju ako želite dojiti, osobito ako se radi o dojenju novorođenčeta ili nedonoščeta.
English: Angiotensin-II is a substance produced in the body that binds to receptors in blood vessels causing them to tighten.
Croatian: Angiotenzin II je tvar koju stvara tijelo i koja se veže na receptore u krvnim žilama te uzrokuje njihovo sužavanje.
English: Hypotension - Volume-depleted patients: Irbesartan Hydrochlorothiazide Zentiva has been rarely associated with symptomatic hypotension in hypertensive patients without other risk factors for hypotension.
Croatian: Hipotenzija - bolesnici s hipovolemijom: Irbesartan Hydrochlorothiazide Zentiva je rijetko povezan sa simptomatskom hipotenzijom u hipertenzivnih bolesnika koji nemaju druge rizične faktore koji bi uzrokovali hipotenziju.
English: Irbesartan Hydrochlorothiazide Zentiva is used to treat high blood pressure, when treatment with irbesartan or hydrochlorothiazide alone did not provide adequate control of your blood pressure.
Croatian: Irbesartan Hydrochlorothiazide Zentiva se primjenjuje za liječenje visokog krvnog tlaka kad liječenje samo irbesartanom ili samo hidroklorotiazidom ne osigurava odgovarajuću kontrolu krvnog tlaka.
English: As is the case with other medicinal products that affect the renin-angiotensin system, black hypertensive patients have notably less response to irbesartan monotherapy.
Croatian: Kao što je to slučaj i s drugim lijekovima koji utječu na sustav reninangiotenzin, osobe crne rase koje boluju od hipertenzije imaju znatno slabiji odgovor na monoterapiju irbesartanom.
English: Efficacy and safety of Irbesartan Hydrochlorothiazide Zentiva as initial therapy for severe hypertension (defined as SeDBP ≥ 110 mmHg) was evaluated in a multicentre, randomized, doubleblind, active-controlled, 8-week, parallel-arm study.
Croatian: Djelotvornost i sigurnost lijeka Irbesartan Hydrochlorothiazide Zentiva kao inicijalne terapije za tešku hipertenziju (dijastolički tlak u sjedećem položaju ≥ 110 mmHg) ocijenjena je u multicentričnom, randomiziranom, dvostruko-slijepom ispitivanju s aktivnom kontrolom, u trajanju od 8 tjedana, s paralelnom skupinom.
English: The following changes, observed in rats and macaques receiving the irbesartan/hydrochlorothiazide combination at 10/10 and 90/90 mg/kg/day, were also seen with one of the two medicinal products alone and/or were secondary to decreases in blood pressure (no significant toxicologic interactions were observed):
Croatian: Sljedeće promjene, zabilježene kod štakora i makaki majmuna koji su dobivali kombinaciju irbesartana/hidroklorotiazida u dozama od 10/10 i 90/90 mg/kg/dan, također su uočene i kod pojedinačne primjene ovih lijekova i/ili su bile sekundarne sniženju krvnog tlaka (nisu zabilježene značajne toksikološke interakcije):
English: Sanofi Winthrop Industrie 30-36, avenue Gustave Eiffel BP7166 F-37071, 37100 Tours France
Croatian: Sanofi Winthrop Industrie 30-36, avenue Gustave Eiffel, BP 7466 F-37071, 37100 Tours Francuska
English: Because no information is available regarding the use of Irbesartan Hydrochlorothiazide Zentiva during breast-feeding, Irbesartan Hydrochlorothiazide Zentiva is not recommended and alternative treatments with better established safety profiles during breast-feeding are preferable, especially while nursing a newborn or preterm infant.
Croatian: Budući da nema dostupnih podataka o upotrebi lijeka Irbesartan Hydrochlorothiazide Zentiva tijekom dojenja, ne preporučuje se njegova primjena tijekom dojenja i prednost treba dati drugoj terapiji s bolje ustanovljenim profilom sigurnosti primjene, osobito kada se doji novorođenče ili nedonošče.
English: Your doctor will instruct you how to switch from the previous treatment to Irbesartan Hydrochlorothiazide Zentiva.
Croatian: Liječnik će Vas uputiti kako prijeći s prethodnog liječenja na Irbesartan Hydrochlorothiazide Zentiva.
English: Increases in cholesterol and triglyceride levels have been associated with thiazide diuretic therapy; however at the 12.5 mg dose contained in Irbesartan Hydrochlorothiazide Zentiva, minimal or no effects were reported.
Croatian: Povišenje razine kolesterola i triglicerida bilo je povezano s terapijom tiazidima; međutim, pri dozi od 12,5 mg koliko sadrži Irbesartan Hydrochlorothiazide Zentiva, zabilježeni su minimalni učinci ili ih uopće nije bilo.
English: Children should not take Irbesartan Hydrochlorothiazide Zentiva Irbesartan Hydrochlorothiazide Zentiva should not be given to children under 18 years of age.
Croatian: Djeca ne smiju uzimati Irbesartan Hydrochlorothiazide Zentiva Irbesartan Hydrochlorothiazide Zentiva ne smiju uzimati djeca mlađa od 18 godina.
English: Diuretic agents such as the hydrochlorothiazide contained in Irbesartan Hydrochlorothiazide Zentiva may have an effect on other medicines.
Croatian: Diuretičke tvari, kao što je hidroklorotiazid iz lijeka Irbesartan Hydrochlorothiazide Zentiva, mogu imati učinke na druge lijekove.
English: Marketing Authorisation Holder Zentiva k.s.
Croatian: Nositelj odobrenja za stavljanje lijeka u promet Zentiva k.s.
English: Irbesartan Hydrochlorothiazide Zentiva with food and drink Irbesartan Hydrochlorothiazide Zentiva can be taken with or without food.
Croatian: Irbesartan Hydrochlorothiazide Zentiva s hranom i pićem Irbesartan Hydrochlorothiazide Zentiva se može uzeti s hranom ili bez nje.
English: Irbesartan Hydrochlorothiazide Zentiva can be taken once daily, with or without food.
Croatian: Irbesartan Hydrochlorothiazide Zentiva se može uzimati jedanput na dan, s hranom ili bez nje.
English: Such conditions should be corrected before initiating therapy with Irbesartan Hydrochlorothiazide Zentiva.
Croatian: Takva stanja treba korigirati prije započinjanja terapije lijekom Irbesartan Hydrochlorothiazide Zentiva.