FrancophonIA/ELRC3.0 huggingface dataset:
English: It is recommended that the reconstitution of the liposomal suspension should be performed in a laminar flow cabinet utilising sterile gloves using aseptic technique.
Croatian: Preporučuje se da se rekonstituciju liposomalne suspenzije treba izvoditi u kabinetu s laminarnim protokom zraka uz primjenu sterilnih rukavica i aseptičkim postupkom.
English: After removing the needle from the syringe, the syringe should be attached to the filter by opening the filter luer connector cap (figure 1).
Croatian: 6. Nakon što se sa štrcaljke ukloni igla, štrcaljku treba učvrstiti na filtar otvaranjem luer spojnice na filtru (slika 1).
English: Once reconstituted in sodium chloride 9 mg/mL (0.9%) solution, store at room temperature (approximately 20ºC - 25ºC) and use within 6 hours.
Croatian: Nakon pripreme u 0,9%-tnoj (9 mg/ml) otopini natrijeva klorida, čuvati na sobnoj temperaturi (otprilike 20ºC - 25ºC) i upotrijebiti unutar 6 sati.
English: The liposomes were phagocytosed by cells of the reticuloendothelial system.
Croatian: Liposome su fagocitirale stanice retikuloendotelnog sustava.
English: Two patients with pre-existing asthma developed mild to moderate respiratory distress associated with the treatment (see section 4.8).
Croatian: Kod dva bolesnika s postojećom astmom pojavile su se blage do umjerene smetnje disanja povezane s terapijom (vidjeti dio 4.8).
English: What MEPACT contains - The active substance is mifamurtide.
Croatian: Što MEPACT sadrži - Djelatna tvar je mifamurtid.
English: BSA-normalised clearance and half-life were similar across the age range and consistent with that determined in healthy adult subjects, supporting the recommended dose of 2 mg/m
Croatian: BSA-normalizirani klirens i poluvijek bili su slični bez obzira na dob i u skladu s utvrđenim kod odraslih zdravih ispitanika, što govori u prilog preporučenoj dozi od 2 mg/m
English: In a randomised controlled study, the incidence of myeloid malignancy (acute myeloid leukaemia/myelodysplastic syndrome) was the same in patients receiving MEPACT plus chemotherapy as in patients receiving only chemotherapy (2.1%).
Croatian: U randomiziranom kontroliranom ispitivanju, pojavnost mijeloidnih malignosti (akutna mijeloidna leukemija/mijelodisplastični sindrom) bila je jednaka kod bolesnika koji su dobivali MEPACT uz kemoterapiju kao i kod bolesnika koji su primali samo kemoterapiju ( 2,1%).
English: One serious incident of subacute thrombosis was reported in early studies, but no serious cardiac events were associated with mifamurtide in a large randomised controlled study (see section 4.4).
Croatian: U ranim ispitivanjima je zabilježen jedan ozbiljan slučaj subakutne tromboze, no u velikim randomiziranim ispitivanjima nije bilo ozbiljnih srčanih događaja povezanih s mifamurtidom (vidjeti dio 4.4).
English: Rash, Pruritis, Erythema, Alopecia, Dry skin
Croatian: Osip, svrbež, eritem, alopecija, suha koža
English: Mean half-lives of total and free MTP-PE in moderate hepatic impairment were 3.21 hours and 3.15 hours, respectively.
Croatian: Srednja vrijednost poluvijeka ukupnog i slobodnog MTP-PE kod umjerenog oštećenja jetre bila je 3,21 i 3,15 sati.
English: The filter and syringe must not be removed from the vial.
Croatian: Filtar i štrcaljka se ne smiju skinuti s bočice.
English: Confusional state, Depression, Insomnia, Anxiety
Croatian: Stanje konfuzije, depresija, nesanica, anksioznost
English: Also, it has been demonstrated in vitro that high-dose NSAIDs (cyclooxygenase inhibitors) can block the macrophage activating effect of liposomal mifamurtide.
Croatian: Također, in vitro je dokazano da visoke doze NSAIL (inhibitora ciklooksigenaze) mogu zaustaviti djelovanje liposomalnog mifamurtida na aktivaciju makrofaga.
English: Major toxic effects associated with these high daily and cumulative doses of mifamurtide were mainly exaggerated pharmacological effects: pyrexia, signs of pronounced inflammatory response manifested as synovitis, bronchopneumonia, pericarditis and inflammatory necrosis of the liver and bone marrow.
Croatian: Glavni toksični učinci povezani s tim visokim dnevnim i kumulativnim dozama mifamurtida bili su pretjerano farmakološko djelovanje: pireksija, znakovi izraženog upalnog odgovora iskazani kao sinovitis, bronhopneumonija, perikarditis i upalna nekroza jetre i koštane srži.
English: These are typically mild to moderate and transient and can usually be treated by your doctor, e.g. with paracetamol for fever.
Croatian: Oni su blagi do umjereni i prolazni i obično ih liječnik može liječiti, npr. vrućicu paracetamolom.
English: In 28 osteosarcoma patients aged 6 to 39 years serum total (liposomal and free) mifamurtide concentrations declined rapidly with a mean half-life of 2.04 ± 0.456 hours.
Croatian: U 28 bolesnika s osteosarkomom u dobi od 6 do 39 godina serumske koncentracije ukupnog (liposomalnog i slobodnog) mifamurtida su brzo opadale sa srednjim poluvijekom od 2,04 ± 0,456 sati.
English: Moderate hepatic impairment resulted in a small increase in AUCinf of total MTP-PE, with the geometric least square mean ratio (expressed as %) for moderate hepatic impairment in reference to the matched normal hepatic function group being 119% (90% confidence interval [CI]: 94.1%-151%).
Croatian: Umjereno oštećenje jetre rezultiralo je malim povećanjem sistemske izloženosti (AUCinf ) ukupnom MTP-PE, s odnosom geometrijske srednje vrijednosti najmanjeg kvadrata (izraženim kao %) kod umjerenog oštećenja jetre u odnosu na usklađenu skupinu s normalnom funkcijom jetre od 119% (90% interval pouzdanosti [CI]: 94,1%-151%).
English: The liposomal suspension is infused intravenously over about 1 hour.
Croatian: Liposomalna suspenzija se primjenjuje intravenskom infuzijom u trajanju od oko 1 sat.
English: Some very common and common side effects of MEPACT treatment (such as dizziness, vertigo, fatigue and blurred vision) may affect your ability to drive and use machines.
Croatian: Neke vrlo česte i česte nuspojave liječenja lijekom MEPACT (poput omaglice, vrtoglavice, umora i zamućenog vida) mogu utjecati na sposobnost upravljanja vozilima i strojevima.
English: Chemical and physical in-use stability has been demonstrated for 6 hours at room temperature (between approximately 20 C-25 °C).
Croatian: 14. Kemijska i fizikalna stabilnost u primjeni dokazana je tijekom 6 sati na sobnoj temperaturi (između približno 20°C - 25°C).
English: The use of mifamurtide concurrently with ciclosporin or other calcineurin inhibitors is contraindicated due to their hypothesised effect on splenic macrophages and mononuclear phagocytic function (see section 4.3).
Croatian: Istodobna primjena mifamurtida sa ciklosporinom ili drugim inhibitorima kalcineurina je kontraindicirana zbog njihovog pretpostavljenog utjecaja na funkciju makrofaga i mononuklearnih fagocita u slezeni (vidjeti dio 4.3).
English: Do not refrigerate or freeze the solution.
Croatian: Otopinu ne čuvati u hladnjaku i ne zamrzavati.
English: Therefore, MEPACT should not be used during pregnancy and in women of childbearing potential not using effective contraception.
Croatian: Stoga se MEPACT ne smije koristiti u trudnoći i kod žena reproduktivne dobi koje ne koriste učinkovitu kontracepciju.
English: This medicine contains less than 1 mmol sodium (23 mg) per dosage unit.
Croatian: Ovaj lijek sadrži manje od 1 mmol (23 mg) natrija po doznoj jedinici.
English: However, as the variability in pharmacokinetics of mifamurtide is greater in subjects with moderate hepatic impairment (see section 5.2), and safety data in patients with moderate hepatic impairment is limited, caution when administering mifamurtide to patients with moderate hepatic impairment is recommended.
Croatian: Međutim, kako je kod bolesnika s umjerenim oštećenjem jetre veća varijabilnost farmakokinetike mifamurtida (vidjeti dio 5.2), a podaci o sigurnosti primjene kod bolesnika s umjerenim oštećenjem jetre su ograničeni, preporučuje se oprez pri primjeni mifamurtida kod bolesnika s umjerenim oštećenjem jetre.
English: If not used immediately, the reconstituted, filtered and diluted solution in-use storage times and conditions prior to use of the reconstituted product must not be longer than 6 hours at 25 ºC.
Croatian: Ako se ne primijeni odmah, vrijeme čuvanja i uvjeti čuvanja rekonstituirane, profiltrirane i razrijeđene otopine prije primjene rekonstituiranog lijeka ne smiju prijeći 6 sati na temperaturi od 25°C.
English: The reconstituted, filtered and diluted suspension for infusion is a homogenous, white to off-white, opaque liposomal suspension, free of visible particles and free of foam and lipid lumps.
Croatian: Rekonstituirana, profiltrirana i razrijeđena suspenzija za infuziju je homogena, bijela do bjelkasta, mutna liposomalna suspenzija, bez vidljivih čestica te bez pjene i nakupina lipida.
English: if you develop chills or shivering, or feel warm.
Croatian: - ako se pojavi zimica, drhtanje ili osjećaj vrućine.
English: There was no effect of mild (50 mL/min ≤ creatinine clearance [CLcr] ≤ 80 mL/min) or moderate (30 mL/min ≤ CLcr < 50 mL/min) renal insufficiency on the clearance of total MTP-PE, when compared with that observed in healthy adult subjects with normal renal function (CLcr > 80 mL/min).
Croatian: Nije bilo utjecaja blagog (50 ml/min ≤ klirens kreatinina [CLcr] ≤ 80 ml/min) ili umjerenog (30 ml/min ≤ CLcr < 50 ml/min) oštećenja bubrega na klirens ukupnog MTP-PE u usporedbi s onim opaženim u zdravih odraslih ispitanika s normalnom funkcijom bubrega (CLcr > 80 ml/min).
English: Signs and symptoms that were associated with higher doses and/or were dose limiting were not life-threatening, and included fever, chills, fatigue, nausea, vomiting, headache and hypoor hypertension.
Croatian: Znakovi i simptomi koji su bili povezani s višim dozama i/ili su ograničavali dozu nisu bili po život opasni, a uključivali su vrućicu, zimicu, umor, mučninu, povraćanje, glavobolju i hipotenziju ili hipertenziju.
English: One patient in the phase III study experienced 2 episodes of grade 4 seizure while on study therapy with chemotherapy and mifamurtide.
Croatian: Jedan bolesnik iz ispitivanja faze III imao je 2 epizode epileptičkog napadaja 4. stupnja tijekom liječenja kemoterapijom i mifamurtidom.
English: It should be used with caution in patients with a history of autoimmune, inflammatory or other collagen diseases.
Croatian: Lijek treba koristiti s oprezom kod bolesnika s autoimunim, upalnim ili drugim kolagenskim bolestima u anamnezi.
English: Mifamurtide was studied as a single agent in 248 patients with mostly advanced malignancies during the early, single arm phase I and II clinical studies.
Croatian: Mifamurtid je ispitivan kao jedini lijek u liječenju 248 bolesnika s pretežno uznapredovalim zloćudnim bolestima u ranom kliničkom ispitivanju faze I i II sa jednom skupinom.
English: Respiratory disorders, including dyspnoea (21%), cough (18%) and tachypnoea (13%) were very commonly reported, and 2 patients with pre-existing asthma developed mild to moderate respiratory distress associated with MEPACT treatment in a phase II study.
Croatian: Poremećaji dišnog sustava, uključujući dispneju (21%), kašalj (18%) i tahipneju (13%) prijavljivani su vrlo često, a 2 bolesnika s prethodno prisutnom astmom su u ispitivanju faze II razvila blage do umjerene smetnje disanja povezane s liječenjem lijekom MEPACT.
English: In vitro-treated human monocytes killed allogeneic and autologous tumour cells (including melanoma, ovarian, colon, and renal carcinoma), but had no toxicity towards normal cells.
Croatian: In vitro tretirani ljudski monociti ubijali su alogene i autologne tumorske stanice (uključujući melanom, karcinom jajnika, kolona i bubrega), ali nisu toksično djelovali na normalne stanice.
English: It is recommended to separate the times of administration of MEPACT and doxorubicin or other medicines if used in the same chemotherapy treatment regimen.
Croatian: Preporučuje se razdvojiti vrijeme primjene lijeka MEPACT i doksorubicina ili drugih lijekova ako se koriste u istom protokolu kemoterapije.
English: Leukopenia, Thrombocytopenia, Granulocytopenia, Febrile neutropenia
Croatian: Leukopenija, trombocitopenija, granulocitopenija, febrilna neutropenija
English: No dedicated fertility studies have been conducted with mifamurtide (see section 5.3).
Croatian: Nisu provedena namjenska ispitivanja plodnosti povezana s mifamurtidom (vidjeti dio 5.3).
English: Mean half-lives of total and free MTP-PE in mild hepatic impairment were 2.02 hours and 1.99 hours, respectively, and were comparable to those in subjects with normal hepatic function (2.15 hours and 2.26 hours, respectively).
Croatian: Srednja vrijednost poluvijeka ukupnog i slobodnog MTP-PE kod blagog oštećenja jetre bila je 2,02 sata i 1,99 sati te je bila usporediva s onom kod ispitanika s normalnom funkcijom jetre (2,15 sati i 2,26 sata).
English: The following events were also observed: haemorrhage and prolongation of coagulation times, infarcts, morphological changes in the wall of small arteries, oedema and congestion of the central nervous system, minor cardiac effects, and slight hyponatraemia.
Croatian: Uočeni su i sljedeći događaji: krvarenje i produljeno vrijeme zgrušavanja, infarkti, morfološke promjene stijenki malih arterija, edem i kongestija središnjeg živčanog sustava, manji učinci na srce i blaga hiponatremija.
English: In addition, pericardial effusion is a listed ADR for another immunostimulant, i.e. aldesleukin.
Croatian: Uz to, perikardijalni izljev naveden je kao nuspojava drugog imunostimulatora, aldesleukina.
English: MEPACT is then infused directly into your vein (intravenous) over about 1 hour.
Croatian: MEPACT se zatim daje infuzijom u venu (intravenski) u trajanju od 1 sata.
English: The desired dose may be withdrawn from the vial by inverting the vial and slowly pulling back on the syringe plunger (figure 3).
Croatian: Željena doza može se izvući iz bočice okretanjem bočice i polaganim povlačenjem klipa štrcaljke (slika 3).
English: At 6 hours after injection of radiolabelled liposomes containing 1 mg mifamurtide, radioactivity was found in liver, spleen, nasopharynx, thyroid, and, to a lesser extent, in lung.
Croatian: Šest sati nakon injiciranja radioaktivno označenih liposoma koji sadrže 1 mg mifamurtida, radioaktivnost je zabilježena u jetri, slezeni, nazofarinksu, štitnoj žlijezdi i u manjem opsegu u plućima.
English: The pharmacokinetics of mifamurtide have been characterised in healthy adult subjects following a 4 mg intravenous infusion and in paediatric and adult patients with osteosarcoma following a 2 mg/m intravenous infusion.
Croatian: Farmakokinetika mifamurtida ispitana je u zdravih odraslih ispitanika nakon intravenske infuzije 4 mg, kao i u pedijatrijskih i odraslih bolesnika s osteosarkomom nakon intravenske infuzije 2 mg/m
English: Because mifamurtide acts through stimulation of the immune system, the chronic or routine use of corticosteroids should be avoided during treatment with mifamurtide.
Croatian: Budući da se djelovanje mifamurtida temelji na stimulaciji imunološkog sustava, tijekom liječenja mifamurtidom treba izbjegavati kroničnu ili rutinsku primjenu kortikosteroida.
English: Before using MEPACT, you should discuss with your doctor whether you should take medicine for your asthma when using MEPACT.
Croatian: Prije primjene lijeka MEPACT morate razgovarati s liječnikom smijete li istodobno s lijekom MEPACT uzimati svoj lijek za astmu.
English: In a large controlled randomised study, mifamurtide used at the recommended dose and schedule with other medicinal products that have known renal (cisplatin, ifosfamide) or hepatic (high-dose methotrexate, ifosfamide) toxicities did not exacerbate those toxicities and there was no need to adjust mifamurtide dose.
Croatian: U velikom kontroliranom randomiziranom ispitivanju, mifamurtid primijenjen u preporučenoj dozi i prema preporučenom rasporedu s drugim lijekovima koji su toksični za bubrege (cisplatin, ifosfamid) ili jetru (metotreksat u visokoj dozi, ifosfamid) nije pojačao toksičnost i nije bilo potrebe za prilagodbu doze mifamurtida.
English: The no-adverse-effect level for mifamurtide in animals corresponds roughly to the 2 mg/m2 recommend dose for humans.
Croatian: Razina mifamurtida koja ne izaziva nuspojave kod životinja približno odgovara preporučenoj dozi za ljude od 2 mg/m2.
English: Therefore, the use of high-dose NSAIDs is contraindicated (see section 4.3).
Croatian: Stoga je primjena visokih doza NSAIL kontraindicirana (vidjeti dio 4.3).
English: Each carton contains 1 vial and 1 single-use, non-pyrogenic, sterile filter for MEPACT supplied in a PVC-grade blister.
Croatian: Jedna kutija sadrži 1 jednu bočicu i 1 jednokratni, nepirogeni sterilni filtar za MEPACT pakiran u PVC blister.
English: Patients with a history of venous thrombosis, vasculitis or unstable cardiovascular disorders should be closely monitored during mifamurtide administration.
Croatian: Bolesnike koji u anamnezi imaju vensku trombozu, vaskulitis ili nestabilnu kardiovaskularnu bolest treba tijekom primjene mifamurtida pomno nadzirati.
English: The patient experienced shaking, chills, fever, nausea, vomiting, uncontrollable coughing, shortness of breath, cyanotic lips, dizziness, weakness, hypotension, tachycardia, hypertension and hypothermia leading to study discontinuation.
Croatian: Bolesnik je imao drhtavicu, zimicu, vrućicu, mučninu, povraćanje, nekontrolirani kašalj, nedostatak zraka, cijanotičke usne, omaglicu, slabost, hipotenziju, tahikardiju, hipertenziju i hipotermiju što je dovelo do isključenja iz ispitivanja.
English: Occasional allergic reactions have been associated with mifamurtide treatment, including rash, shortness of breath and grade 4 hypertension (see section 4.8).
Croatian: S liječenjem mifamurtidom povezane su povremene alergijske reakcije, uključujući osip, nedostatak zraka i hipertenziju stupnja 4 (vidjeti dio 4.8).
English: MEPACT must be reconstituted, filtered using the filter provided and further diluted using aseptic technique, prior to administration.
Croatian: MEPACT se mora rekonstituirati, profiltrirati kroz priloženi filtar i dalje razrijediti aseptičkim postupkom, prije primjene.
English: Additionally, the geometric mean plasma AUCinf of free (non-liposome associated) MTP-PE in mild and moderate hepatic impairment were 47% higher than the corresponding values in the matched normal hepatic function groups.
Croatian: Dodatno, geometrijska srednja vrijednost plazmatskog AUCinf slobodnog (ne-liposomalnog) MTP-PE kod blagog i umjerenog oštećenja jetre bila je 47% viša od odgovarajućih vrijednosti u skupini s normalnom funkcijom jetre.
English: System organ class
Croatian: Klasifikacija organskih sustava Kategorije učestalosti
English: It can also be administered as an outpatient.
Croatian: Može ga se davati i ambulantno.
English: Hepatic pain
Croatian: Hepatička bol
English: The recommended dose of MEPACT is 2 mg mifamurtide/m body surface area.
Croatian: Preporučena doza lijeka MEPACT je 2 mg mifamurtida/m tjelesne površine.
English: An osteosarcoma patient in a phase II study who had high creatinine level at enrolment showed an increase in blood urea and blood creatinine which was associated with mifamurtide use.
Croatian: Kod jednog bolesnika s osteosarkomom u ispitivanju faze II koji je imao zabilježenu visoku vrijednost kreatinina, pokazalo se da je liječenje mifamurtidom bilo povezano s povećanjem ureje i kreatinina u krvi.
English: Powder for concentrate for dispersion for infusion Pack of 1 vial of powder, 1 sterile filter
Croatian: Prašak za koncentrat za disperziju za infuziju Pakiranje s 1 bočicom praška,1 sterilni filtar
English: Delpharm Novara S.r.l.
Croatian: Delpharm Novara S.r.l. Via Crosa, 86
English: Concurrent use with high-dose non-steroidal-anti-inflammatory drugs (NSAIDs, cyclooxygenase inhibitors) (see section 4.5).
Croatian: Istodobna primjena s visokim dozama nesteroidnih protuupalnih lijekova (NSAIL, inhibitori ciklooksigenaze) (vidjeti dio 4.5).
English: MEPACT contains sodium
Croatian: MEPACT sadrži natrij
English: Gastrointestinal disorders were frequently associated with mifamurtide administration, including nausea (57%) and vomiting (44%) in about half of patients, constipation (17%), diarrhoea (13%) and abdominal pain (see section 4.4).
Croatian: Poremećaji probavnog sustava su često bili povezani s primjenom mifamurtida, uključujući mučninu (57%) i povraćanje (44%) u oko polovice bolesnika, zatvor (17%), proljev (13%) i abdominalnu bol (vidjeti dio 4.4).
English: In patients with a history of asthma or other chronic obstructive pulmonary disease, consideration should be given to administration of bronchodilators on a prophylactic basis.
Croatian: Kod bolesnika s astmom ili drugom kroničnom opstruktivnom bolesti pluća u anamnezi, potrebno je razmisliti o profilaktičkoj primjeni bronhodilatatora.
English: For intravenous use after reconstitution, filtering using the filter provided and further dilution.
Croatian: Za intravensku primjenu nakon rekonstitucije, filtriranja priloženim filtrom i dodatnog razrjeđivanja.
English: Concurrent use with ciclosporin or other calcineurin inhibitors (see section 4.5).
Croatian: Istodobna primjena s ciklosporinom ili drugim inhibitorima kalcineurina (vidjeti dio 4.5).
English: If your problems increase, you should contact your doctor, as these may have been caused by MEPACT when used with chemotherapy.
Croatian: Ako se poteškoće pogoršaju, trebate se obratiti svom liječniku, jer to može biti uzrokovano lijekom MEPACT kada se primjenjuje uz kemoterapiju.
English: Dyspnoea, Tachypnoea, Cough
Croatian: Dispneja, tahipneja, kašalj
English: All patients received a total dose of cisplatin of 480 mg/m2 as part of their induction (neoadjuvant) and/or maintenance (adjuvant) chemotherapy regimen.
Croatian: Svi bolesnici primili su ukupnu dozu cisplatina od 480 mg/m kao dio neoadjuvantnog i/ili adjuvantnog kemoterapijskog protokola.
English: It is recommended to separate the administration times of mifamurtide and doxorubicin or other lipophilic medicinal products if used in the same chemotherapy regimen.
Croatian: Preporučuje se razdvojiti vrijeme primjene mifamurtida i doksorubicina ili drugih lipofilnih lijekova koji se koriste u istom režimu kemoterapije.
English: In vitro interaction studies showed that liposomal and non-liposomal mifamurtide do not inhibit the metabolic activity of cytochrome P450 in pooled human liver microsomes.
Croatian: In vitro ispitivanja interakcija pokazala su da liposomalni i neliposomalni mifamurtid ne inhibira metaboličku aktivnost citokroma P450 u združenim ljudskim mikrosomima jetre.
English: There are no clinically meaningful effects of mild to moderate renal (creatinine clearance (CrCL) ≥ 30 mL/min) or hepatic impairment (Child-Pugh class A or B) on the pharmacokinetics of mifamurtide; therefore, dose adjustments are not necessary for these patients.
Croatian: Nema klinički značajnog utjecaja blagog do umjerenog oštećenja bubrega (klirens kreatinina ≥ 30 ml/min) ili jetre (Child-Pugh stadij A ili B) na farmakokinetiku mifamurtida; stoga kod tih bolesnika nije potrebna prilagodba doze.
English: The vial should then be shaken vigorously for 1 minute while keeping the filter and syringe attached.
Croatian: 9. Bočicu zatim treba snažno tresti 1 minutu držeći filtar i štrcaljku i dalje pričvršćene.
English: Anaemia has very commonly been reported when mifamurtide is used in conjunction with chemotherapeutic agents.
Croatian: Anemija je bila vrlo često prijavljivana kad se mifamurtid koristio istodobno s kemoterapeuticima.
English: These are typically mild to moderate, transient in nature and generally respond to palliative treatment (e.g., paracetamol for fever).
Croatian: Bile su uglavnom blage do umjerene, prolazne prirode i općenito s dobrim odgovorom na palijativno liječenje (npr. paracetamol za vrućicu).
English: Dizziness, vertigo, fatigue and blurred vision have shown as very common or common undesirable effects of mifamurtide treatment.
Croatian: Omaglica, vrtoglavica, umor i zamućen vid pokazali su se kao vrlo česte ili česte nuspojave liječenja mifamurtidom.