FrancophonIA/ELRC3.0 huggingface dataset:
English: No data are available on which to make a dose recommendation for patients over the age of 65 years (see section 5.2).
Croatian: Nema dostupnih podataka na osnovu kojih bi se mogla preporučiti doza za bolesnike starije od 65 godina (vidjeti dio 5.2).
English: Tybost comes in bottles of 30 tablets (with a silica gel sachet or canister that must be kept in the bottle to help protect your tablets).
Croatian: Tybost dolazi u bočicama od 30 tableta (s vrećicom ili spremnikom silika gela koji se mora čuvati u bočici radi zaštite tableta).
English: • oral or implanted hormonal contraceptives used to prevent pregnancy
Croatian: • oralni ili implantirani hormonalni kontraceptivi koji se primjenjuju za sprječavanje trudnoće
English: The serum digoxin concentrations should be monitored and used for titration of digoxin dose to obtain the desired clinical effects.
Croatian: Serumske koncentracije digoksina se mora nadzirati i koristiti za titraciju doze digoksina radi postizanja željenih kliničkih učinaka.
English: It is important not to miss a dose of Tybost.
Croatian: Važno je da ne propustite dozu lijeka Tybost.
English: Pharmacotherapeutic group: All other therapeutic products, ATC code: V03AX03
Croatian: Farmakoterapijska skupina: svi drugi terapijski pripravci, ATK oznaka: V03AX03
English:  If any of these applies to you, talk to your doctor before taking Tybost.
Croatian: Ako se išta od ovog odnosi na Vas, razgovarajte sa svojim liječnikom prije nego uzmete Tybost.
English: CCR5 Antagonists Maraviroc
Croatian: Antagonisti CCR5 Maravirok
English: There are some medicines that should never be taken with Tybost.
Croatian: Neke se lijekove nikada ne smije uzeti s lijekom Tybost.
English: These interactions are based on either drug interaction studies or predicted interactions due to the expected magnitude of interaction and potential for serious and/or life-threatening events or loss of efficacy.
Croatian: Te se interakcije temelje ili na ispitivanjima interakcija lijekova ili na predviđenim interakcijama zbog očekivane veličine interakcije i potencijala za ozbiljne i/ili po život opasne događaje ili gubitak djelotvornosti.
English: The amounts of these medicines in your blood may decrease during pregnancy, which may stop them from working properly.
Croatian: Tijekom trudnoće se količina ovih lijekova u krvi može sniziti, zbog čega mogu prestati ispravno djelovati.
English: Effects on the liver
Croatian: Učinci na jetru
English: For these sedatives/hypnotics, dose reduction may be necessary and concentration monitoring is recommended.
Croatian: Za te sedative/hipnotike, može biti potrebno smanjenje doze i preporučuje se praćenje koncentracije.
English: Table 2: Interactions between cobicistat and other medicinal products
Croatian: Tablica 2: Interakcije između kobicistata i drugih lijekova
English: It does this by slowing down the breakdown of atazanavir and darunavir which will make them stay in the body for longer.
Croatian: To čini tako što usporava razgradnju atazanavira i darunavira te se oni dulje zadržavaju u tijelu.
English: Cobicistat is primarily metabolised and eliminated by the liver.
Croatian: Kobicistat se prvenstveno metabolizira i eliminira putem jetre.
English:  If any of these applies to you, you should not take Tybost and you should tell your doctor immediately.
Croatian: Ako se bilo što od ovoga odnosi na Vas, ne smijete uzimati Tybost i morate odmah o tome obavijestiti svog liječnika.
English: • sleep disorder
Croatian: • poremećaji spavanja
English: • HMG Co-A reductase inhibitors: lovastatin, simvastatin
Croatian: • inhibitori HMG-CoA reduktaze: lovastatin, simvastatin
English: The European Medicines Agency has deferred the obligation to submit the results of studies with cobicistat in one or more subsets of the paediatric population in treatment of HIV-1 infection (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove odgodila je obvezu podnošenja rezultata ispitivanja kobicistata u jednoj ili više podskupina pedijatrijske populacije za liječenje HIV-1 infekcije (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: If you forget to take Tybost
Croatian: Ako ste zaboravili uzeti Tybost
English: Always keep enough Tybost so you don't run out.
Croatian: Uvijek imajte dovoljno lijeka Tybost tako da Vam ne ponestane.
English: depression, sleep disorder Nervous system disorders: Common:
Croatian: depresija, poremećaj spavanja Poremećaji živčanog sustava: Često:
English: The median terminal plasma half-life of cobicistat following administration of Tybost is approximately 3-4 hours.
Croatian: Medijan terminalnog poluvijeka kobicistata u plazmi nakon primjene lijeka Tybost iznosi oko 3-4 sata.
English: If you are taking Tybost with atazanavir your doctor will discuss the potential benefits and risks of taking Tybost to you and your child.
Croatian: Ako uzimate Tybost s atazanavirom, liječnik će Vam objasniti moguće koristi i rizike uzimanja lijeka Tybost za Vas i Vaše dijete.
English: Black or African Heritage Asian
Croatian: Rasna pripadnost bijelci crnci ili afričkog podrijetla azijati drugi
English: Further dose reduction of rifabutin has not been studied.
Croatian: Dodatno smanjenje doze rifabutina nije ispitivano.
English: As cobicistat is highly bound to plasma proteins, it is unlikely that it will be significantly removed by hemodialysis or peritoneal dialysis.
Croatian: Budući da je kobicistat u visokom postotku vezan za proteine plazme, nije vjerojatno da će se značajno ukloniti hemodijalizom ili peritonejskom dijalizom.
English: Norgestimate/Ethinyloestradiol Interaction not studied.
Croatian: Norgestimat/etinilestradiol Interakcija nije ispitana.
English: • within 12 hours of the time you usually take Tybost, you must take the tablet as soon as possible.
Croatian: • u periodu unutar 12 sati od vremena kad obično uzimate Tybost, tabletu morate uzeti što prije.
English: Cobicistat is not expected to induce CYP3A4 or P-gp (MDR1).
Croatian: Ne očekuje se da će kobicistat inducirati CYP3A4 ili P-gp (MDR1).
English: Cobicistat levels decrease and may not provide sufficient boosting.
Croatian: Razina kobicistata se snižava pa možda neće osigurati dovoljno pojačanje učinka.
English: • neuroleptics/antipsychotics: pimozide, lurasidone
Croatian: • neuroleptici/antipsihotici: pimozid, lurasidon
English: Week 144
Croatian: 144. tjedan
English: In order to avoid transmission of HIV to the infant it is recommended that HIV infected women do not breast-feed their infants under any circumstances.
Croatian: Kako bi se izbjegao prijenos HIV-a na dojenče preporučuje se da žene zaražene HIV-om ne doje svoju dojenčad ni u kojim okolnostima.
English: Following oral administration of [14C]cobicistat, 99% of circulating radioactivity in plasma was unchanged cobicistat.
Croatian: Nakon peroralne primjene [14C]kobicistata, 99% cirkulirajuće radioaktivnosti u plazmi bio je nepromijenjeni kobicistat.
English: Concentrations of these medicinal products may be increased when co-administered with Tybost resulting in the potential for increased adverse events usually associated with these anticancer medicinal products.
Croatian: Koncentracije ovih lijekova mogu se povećati kod istodobne primjene s lijekom Tybost što dovodi do potencijala za pojačane štetne događaje koji su obično povezani s ovim lijekovima protiv raka.
English: A long term carcinogenicity study of cobicistat in rats revealed tumourigenic potential specific for this species that is regarded as of no relevance for humans.
Croatian: Dugoročno ispitivanje kancerogenosti kobicistata u štakora otkrilo je tumorogeni potencijal specifičan za tu vrstu koji se ne smatra značajnim za ljude.
English: If the combination is needed, the recommended dose of rifabutin is 150 mg 3 times per week on set days (for example MondayWednesday-Friday).
Croatian: Ako je kombinacija ipak potrebna, preporučena doza rifabutina je 150 mg triput tjedno u određene dane (npr. ponedjeljkom, srijedom i petkom).
English: • clarithromycin and rifabutin, medicines used to treat bacterial infections including tuberculosis
Croatian: • klaritromicin i rifabutin, lijekovi koji se primjenjuju za liječenje bakterijskih infekcija, uključujući i tuberkulozu
English: • Tybost must be taken with atazanavir (300 mg) or darunavir (800 mg).
Croatian: • Tybost se mora uzeti s atazanavirom (300 mg) ili darunavirom (800 mg).
English: Alternative forms of contraception should be considered (see section 4.5).
Croatian: Potrebno je razmotriti druge oblike kontracepcije (vidjeti dio 4.5).
English: ENDOTHELIN RECEPTOR ANTAGONISTS Bosentan
Croatian: ANTAGONISTI RECEPTORA ENDOTELINA
English: Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
Croatian: Unutar svake skupine po učestalosti, nuspojave su prikazane u padajućem nizu prema ozbiljnosti.
English: This may stop your medicines from working properly, or may make any side effects worse.
Croatian: To može spriječiti ispravno djelovanje lijekova ili pogoršati nuspojave.
English: The lowest dose of digoxin should initially be prescribed.
Croatian: Na početku liječenja se mora propisati najnižu dozu digoksina.
English: It is taken with atazanavir or darunavir (both protease inhibitors) and acts as a booster (enhancer) to help improve their effect.
Croatian: Uzima se s atazanavirom ili darunavirom (oba su inhibitori proteaze) i djeluje kao pojačivač kako bi poboljšao njihov učinak.
English: • protein in the urine (proteinuria)
Croatian: • proteini u urinu (proteinurija)
English: Contraception requirements
Croatian: Kontracepcijski zahtjevi
English: If overdose occurs the patient must be monitored for evidence of toxicity (see section 4.8).
Croatian: U slučaju predoziranja bolesnik mora biti pod nadzorom zbog znakova toksičnosti (vidjeti dio 4.8).
English: An increase from baseline in serum creatinine solely due to cobicistat's inhibitory effect generally does not exceed 0.4 mg/dl.
Croatian: Povećana razina u odnosu na početnu vrijednost serumskog kreatinina isključivo zbog inhibitornog učinka kobicistata općenito ne prelazi 0,4 mg/dl.
English: Available pharmacodynamic/toxicological data in animals have shown excretion of cobicistat/metabolites in milk.
Croatian: Dostupni farmakodinamički/toksikološki podaci u životinja pokazuju da se kobicistat/metaboliti izlučuju u mlijeko.
English: Voriconazole should not be used unless the possible benefit is considered to outweigh the risks associated with the unpredictable effect on plasma concentrations.
Croatian: Vorikonazol se ne smije koristiti osim kada je moguća korist veća od rizika koji se povezuju s nepredviđenim učinkom na koncentracije u plazmi.
English: Animal studies do not indicate direct or indirect harmful effects of cobicistat with respect to reproductive toxicity (see section 5.3).
Croatian: Ispitivanja na životinjama ne ukazuju na izravan ili neizravan štetan učinak kobicistata na reproduktivnu toksičnost (vidjeti dio 5.3).
English: Macrolide antibiotics Clarithromycin
Croatian: Makrolidni antibiotici Klaritromicin
English: Then take the next dose as usual in combination with atazanavir or darunavir.
Croatian: Zatim uzmite sljedeću dozu u uobičajeno vrijeme u kombinaciji s atazanavirom ili darunavirom.
English: The silica gel desiccant is contained in a separate sachet or canister and should not be swallowed.
Croatian: Sredstvo za sušenje od silika gela nalazi se u posebnoj vrećici ili spremniku i ne smije se progutati.
English: If you are affected while taking Tybost, do not drive and do not use any tools or machines.
Croatian: Ako se i kod Vas pojavi omaglica tijekom uzimanja lijeka Tybost, nemojte upravljati vozilima niti koristiti alate ili strojeve.
English: Median age, years (min-max)
Croatian: Demografske značajke Medijan dobi, godine (min.-maks.)
English: • PDE-5 inhibitors: sildenafil for treatment of pulmonary arterial hypertension
Croatian: • PDE-5 inhibitori: sildenafil za liječenje plućne arterijske hipertenzije
English: EU/1/13/872/001 30 film-coated tablets EU/1/13/872/002 90 (3 bottles of 30) film-coated tablets
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/13/872/001 30 filmom obloženih tableta EU/1/13/872/002 90 (3 bočice od 30) filmom obloženih tableta
English: DOAC = direct oral anticoagulant 1 Study was conducted with tenofovir disoproxil fumarate
Croatian: DOAC = direktni oralni antikoagulans 1Ispitivanje je provedeno s tenofovirdizoproksilfumaratom
English: In rats, ossification changes in the spinal column and sternebra of foetuses occurred at a dose that produced significant maternal toxicity.
Croatian: Osifikacijske promjene na kralježnici i sternebri fetusa štakora pojavile su se pri dozi koja je uzrokovala značajnu maternalnu toksičnost.
English: Tybost may interact with other substances.
Croatian: Tybost može ući u interakciju s drugim tvarima.
English: Ex vivo rabbit studies and in vivo dog studies suggest that cobicistat has a low potential for QT prolongation, and may slightly prolong the PR interval and decrease left ventricular function at mean concentrations at least 10-fold higher than the human exposure at the recommended 150 mg daily dose.
Croatian: Ex vivo ispitivanja na kunićima i in vivo ispitivanja na psima navode da kobicistat ima niski potencijal za prolongaciju QT-a, te može malo produljiti PR interval i smanjiti funkciju lijeve klijetke pri srednjim vrijednostima koncentracija najmanje 10 puta većim od ljudske izloženosti pri preporučenoj dnevnoj dozi od 150 mg.
English: If you are a woman with HIV it is recommended that you do not breast-feed to avoid passing the virus to the baby through your breast milk.
Croatian: Ako ste žena zaražena HIV-om, preporučuje se da ne dojite kako bi se izbjegla mogućnost da virus prijeđe na dojenče putem majčinog mlijeka.
English: Eye disorders: Very common:
Croatian: Poremećaji oka: Vrlo često:
English: These medicines are used to treat allergies, asthma, inflammatory bowel diseases, inflammatory conditions of the eyes, joints and muscles and other inflammatory conditions.
Croatian: Ti se lijekovi primjenjuju za liječenje alergija, astme, upalnih bolesti crijeva, upalnih stanja očiju, zglobova i mišića te drugih upalnih stanja.
English: Dose titration may be required for most medicinal products of the SSRI class, when co-administered with Tybost.
Croatian: Može biti potrebna titracija doze za većinu lijekova iz klase SSRI kad se primjenjuju istodobno s lijekom Tybost.
English: Tybost is used in adults aged 18 years and over who are infected with HIV, the virus that causes acquired immunodeficiency syndrome (AIDS).
Croatian: Tybost se koristi za primjenu u odraslih u dobi od 18 godina i više zaraženih virusom HIV-a koji uzrokuje sindrom stečene imunodeficijencije (SIDA).
English: • 12 hours or more after the time you usually take Tybost, then do not take the missed dose.
Croatian: • a prošlo je 12 sati ili više od vremena kada obično uzimate Tybost, propuštenu dozu nemojte uzeti.
English: • ciclosporin, sirolimus and tacrolimus, medicines used to control your body's immune response after a transplant
Croatian: • ciklosporin, sirolimus i takrolimus, lijekovi koji se primjenjuju za kontroliranje imunološkog odgovora Vašeg tijela nakon transplantacije
English: Of these 692 patients, 613 (300 atazanavir/cobicistat and 313 atazanavir/ritonavir) and 496 (250 atazanavir/cobicistat and 246 atazanavir/ritonavir) received at least 48 and 144 weeks of treatment, respectively.
Croatian: Od ovih 692 bolesnika 613 (300 atazanavir/kobicistat i 313 atazanavir/ritonavir), odnosno 496 (250 atazanavir/kobicistat i 246 atazanavir/ritonavir) primili su barem 48, odnosno 144 tjedna liječenja.
English: Cobicistat has no detectable antiviral activity against HIV-1, HBV or HCV and does not antagonise the antiviral effect of HIV inhibitors.
Croatian: Za kobicistat nije otkrivena antivirusna aktivnost protiv HIV-1, HBV ili HCV te on ne antagonizira antivirusni učinak HIV inhibitora.
English: Some examples include, but are not limited to, etravirine, efavirenz, nevirapine, and bosentan (see Table 2).
Croatian: Neki primjeri uključuju, ali nisu ograničeni na etravirin, efavirenz, nevirapin i bosentan (vidjeti Tablicu 2).
English: No dose adjustment of methadone is required.
Croatian: Prilagodba doze metadona nije potrebna.
English: At week 96 the mean change in serum creatinine was 0.07 ± 0.15 mg/dl and the mean change in eGFR by Cockcroft-Gault method was -6.2 ± 9.07 ml/min.
Croatian: U 96. tjednu srednja vrijednost promjene razine serumskog kreatinina bila je 0,07 ± 0,15 mg/dl, a srednja vrijednost promjene eGFR-a izračunatog metodom Cockcroft-Gault bila je -6,2 ± 9,07 ml/min.
English: Cobicistat and atazanavir should only be used during pregnancy if the potential benefit justifies the potential risk to the foetus and mother.
Croatian: Kobicistat i atazanavir smiju se primjenjivati u trudnoći samo ako moguća korist opravdava mogući rizik za fetus i majku.
English: Virologic response rate was evaluated in both treatment arms and virologic response was defined as achieving an undetectable viral load (< 50 HIV-1 RNA copies/ml).
Croatian: Stopa virološkog odgovora procijenjena je u obje skupine liječenja i virološki odgovor definiran je kao postizanje nedetektabilnog virusnog opterećenja (< 50 HIV-1 RNK kopija/ml).
English: If a patient misses a dose of Tybost by more than 12 hours, the patient should not take the missed dose and simply resume the usual dosing schedule.
Croatian: Ako bolesnik propusti uzeti dozu lijeka Tybost u roku duljem od 12 sati, bolesnik ne treba uzeti propuštenu dozu nego jednostavno nastaviti uzimati doze prema uobičajenom rasporedu.
English: For these neuroleptics, consider reducing the dose of the neuroleptic upon co-administration with Tybost.
Croatian: Za ove neuroleptike razmotrite smanjenje doze neuroleptika kod istodobne primjene s lijekom Tybost.
English: However, a higher percentage of subjects in the cobicistat-boosted group had increases in total bilirubin > 2 x ULN than those in the ritonavir-boosted group (88.0% versus 80.9%).
Croatian: Međutim, veći postotak ispitanika u skupini koja je primala kobicistatom pojačani lijek je imalo povećanja u ukupnom bilirubinu > 2 x GGN, nego oni u skupini koja je primala ritonavirom pojačani lijek (88,0% naspram 80,9%).
English: • Talk to your doctor or pharmacist if you have or have had severe liver disease, or if tests have shown problems with your liver.
Croatian: • Razgovarajte sa svojim liječnikom ili ljekarnikom ako imate ili ste imali težu bolest jetre ili ako pretrage pokazuju probleme s jetrom.
English: The substantial reduction in darunavir exposure may result in virological failure and an increased risk of mother-to-child transmission of HIV infection.
Croatian: Znatno smanjenje izloženosti darunaviru može dovesti do virološkog neuspjeha i povećanog rizika od prijenosa HIV infekcije s majke na dijete.
English: Recommendation concerning co-administration with cobicistat 150 mg and atazanavir or darunavir
Croatian: Preporuka za istodobnu primjenu uz kobicistat od 150 mg i atazanavir ili darunavir
English: Randomisation was stratified by screening HIV-1 RNA level (≤ 100,000 copies/ml or > 100,000 copies/ml).
Croatian: Randomozacija je stratificirana probiranjem na razinu HIV-1 RNK (≤ 100 000 kopija/ml ili > 100 000 kopija/ml).
English: Plasma levels of cobicistat and consequently of atazanavir may decrease significantly during pregnancy.
Croatian: Razine kobicistata u plazmi i, posljedično, atazanavira mogu se značajno sniziti tijekom trudnoće.
English: If you accidentally take more than the recommended dose of Tybost you may be at increased risk of experiencing side effects with this medicine (see section 4 of this leaflet).
Croatian: Ako slučajno uzmete više od preporučene doze lijeka Tybost, može Vam se povećati rizik od nuspojava ovog lijeka (pogledajte dio 4 ove upute).
English: Tybost should not be used in combination with other medicinal products containing cobicistat or with ritonavir due to similar effects of cobicistat and ritonavir on CYP3A.
Croatian: Tybost se ne smije primjenjivati u kombinaciji s drugim lijekovima koji sadrže kobicistat ili s ritonavirom zbog sličnih učinaka kobicistata i ritonavira na CYP3A.
English: Cobicistat is 97-98% bound to human plasma proteins and the mean plasma to blood drug concentration ratio was 2.
Croatian: Kobicistat se 97-98% vezuje za proteine u plazmi ljudi, dok je omjer srednje vrijednosti koncentracije lijeka u plazmi i koncentracije lijeka u krvi iznosio 2.
English: Systemic lidocaine Mexiletine
Croatian: Sistemski lidokain lidokain Meksiletin
English: There are currently inadequate data to determine whether co-administration of tenofovir disoproxil and cobicistat is associated with a greater risk of renal adverse reactions compared with regimens that include tenofovir disoproxil without cobicistat.
Croatian: Trenutačno nema odgovarajućih podataka za utvrđivanje je li istodobna primjena tenofovirdizoproksila i kobicistata povezana s većim rizikom bubrežnih nuspojava u usporedbi s režimima koji uključuju tenofovirdizoproksil bez kobicistata.
English: Cobicistat inhibits the transporters P-gp, BCRP, MATE1, OATP1B1 and OATP1B3.
Croatian: Kobicistat inhibira P-gp, BCRP, MATE1, OATP1B1 i OATP1B3 transportere.
English: Darunavir/ritonavir may be considered as an alternative.
Croatian: Kao alternativu može se razmotriti darunavir/ritonavir.
English: PC: {number} SN: {number} NN: {number} [Outer packaging only]
Croatian: NN: {broj} [Samo vanjsko pakiranje]
English: Among the 21 patients, 3 developed the emtricitabine-associated resistance substitution M184V.
Croatian: Od 21 bolesnika, 3 je razvilo rezistentnu supstituciju M184V povezanu s emtricitabinom.
English: It is not known if the active substance in this medicine can pass into human breast milk.
Croatian: Nije poznato može li djelatna tvar iz ovog lijeka prijeći u majčino mlijeko.
English: • antimycobacterials: rifampicin
Croatian: • antimikobakterijski lijekovi: rifampicin
English: Other medicines and Tybost Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, ako ste nedavno uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: PDE-5 inhibitors are primarily metabolised by CYP3A.
Croatian: Inhibitori PDE-5 prvenstveno se metaboliziraju putem CYP3A.
English: Low levels of metabolites are observed in urine and faeces and do not contribute to the CYP3A inhibitory activity of cobicistat.
Croatian: Niske razine metabolita opažene su u urinu i fecesu i ne pridonose inhibitornoj aktivnosti kobicistata na CYP3A.
English: In Study GS-US-216-0114, decreases in estimated creatinine clearance occurred early in treatment with cobicistat, after which they stabilised.
Croatian: U ispitivanju GS-US-216-0114 smanjenja procijenjenog klirensa kreatinina pojavila su se rano kod liječenja kobicistatom nakon čega su se stabilizirala.
English: If the patient misses a dose of Tybost within 12 hours of the time it is usually taken, the patient should take Tybost with food as soon as possible and resume their normal dosing schedule in combination with atazanavir or darunavir.
Croatian: Ako bolesnik propusti uzeti dozu lijeka Tybost unutar 12 sati od uobičajenog vremena uzimanja doze, bolesnik mora što prije uzeti Tybost s hranom i potom ga nastaviti uzimati prema svom uobičajenom rasporedu u kombinaciji s atazanavirom ili darunavirom.
English: HIV-1 RNA < 50 copies/ml Treatment difference -2.2% (95% CI = -7.4%, 3.0%) -2.1% (95% CI = -8.7%, 4.5%)
Croatian: -2,2% (95% CI = -7,4%, 3,0%) -2,1% (95% CI = -8,7%, 4,5%)
English: Therefore, Tybost should not be co-administered with medicinal products that include, but are not limited to, the following (see sections 4.4 and 4.5):
Croatian: Stoga se Tybost ne smije primjenjivati istodobno s lijekovima koji uključuju, ali nisu ograničeni na sljedeće lijekove (vidjeti dijelove 4.4 i 4.5):
English: Selective Serotonin Reuptake Inhibitors (SSRIs) Trazodone
Croatian: Selektivni inhibitori ponovne pohrane serotonina (SSRI) Trazodon