FrancophonIA/ELRC3.0 huggingface dataset:
English: Date of latest renewal: 19 November 2014
Slovenian: Datum prve odobritve: 15. marec 2010 Datum zadnjega podaljšanja: 19. november 2014
English: Do not stop the treatment unless your doctor tells you so.
Slovenian: Ne prekinite zdravljenja, razen če vam tega ne odredi zdravnik.
English: Some other medicines may influence the use of DuoPlavin or vice versa.
Slovenian: Nekatera druga zdravila lahko vplivajo na uporabo zdravila DuoPlavin in obratno.
English: Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/
Slovenian: Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila: http://www.ema.europa.eu/.
English: The safety and efficacy of DuoPlavin in children and adolescents under 18 years old have not been established.
Slovenian: Varnost in učinkovitost zdravila DuoPlavin pri otrocih in mladostnikih mlajših od 18 let nista ugotovljeni.
English: Refer to local requirements for disposal.
Slovenian: Upoštevajte lokalne zahteve za odlaganje.
English: Side effects with frequency not known (frequency cannot be estimated from the available data):
Slovenian: Možni neželeni učinki, katerih pogostnost ni znana (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti):
English: Following toxic doses (10 20 g), the plasma half-life may be increased to over 20 hours.
Slovenian: Po toksičnih odmerkih (10 20 g) se lahko razpolovni čas v plazmi podaljša na več kot 20 ur.
English: • You should tell your doctor - if a surgery (including dental) is planned.
Slovenian: • morate povedati zdravniku: - če imate predvideno kakšno operacijo (vključno z zobozdravstvenim posegom).
English: DuoPlavin is not intended for use in children or adolescents less than 18 years of age.
Slovenian: Zdravilo DuoPlavin ni namenjeno uporabi pri otrocih in mladostnikih, mlajših od 18 let.
English: At low concentrations (<100 micrograms/ml), approximately 90% of salicylic acid is bound to albumin.
Slovenian: Pri nizkih koncentracijah (< 100 g/ml) je približno 90 % salicilne kisline vezane na albumin.
English: Depending on your condition, your doctor will determine the length of time for which you need to take DuoPlavin.
Slovenian: Zdravnik bo glede na vaše stanje določil, koliko časa morate jemati zdravilo DuoPlavin.
English: DuoPlavin is not recommended in this population.
Slovenian: Uporaba zdravila DuoPlavin se v tej populaciji ne priporoča.
English: Interactions with the following medicinal products have been reported with ASA:
Slovenian: Opisane so interakcije med ASA in naslednjimi zdravili:
English: ** Information related to clopidogrel with frequency “not known”.
Slovenian: ** Informacije v povezavi s klopidogrelom s pogostnostjo “ni znana”.
English: The European Medicines Agency has waived the obligation to submit the results of studies with DuoPlavin in all subsets of the paediatric population in the treatment of coronary atherosclerosis (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od obveznosti po predložitvi rezultatov študij zdravila DuoPlavin pri vseh podskupinah pediatrične populacije za zdravljenje koronarne ateroskleroze (glejte poglavje 4.2 za informacije o pediatrični uporabi).
English: DuoPlavin should not be used during the first two trimesters of pregnancy unless the clinical condition of the woman requires treatment with clopidogrel/ASA.
Slovenian: Zdravilo DuoPlavin se ne sme uporabljati v prvih dveh trimesečjih nosečnosti, razen če klinično stanje nosečnice ne zahteva terapije s klopidogrelom / ASA.
English: In patients with ST segment elevation acute myocardial infarction: Therapy should be started as early as possible after symptoms start and continued for at least four weeks.
Slovenian: Pri bolnikih z akutnim miokardnim infarktom z elevacijo ST spojnice: zdravljenje je potrebno začeti čim prej po nastopu simptomov in z njim nadaljevati vsaj štiri tedne.
English: Patients should inform physicians and dentists that they are taking DuoPlavin before any surgery is scheduled and before any new medicinal product is taken.
Slovenian: Bolniki morajo obvestiti zdravnika in zobozdravnika, da jemljejo klopidogrel, pred vsakim načrtovanjem kirurškega posega in preden vzamejo katerokoli novo zdravilo.
English: Due to the presence of both components of the medicinal product, DuoPlavin is contraindicated in case of:
Slovenian: Zaradi vsebnosti obeh učinkovin v zdravilu, je zdravilo DuoPlavin kontraindicirano v primeru:
English: If patients must temporarily stop antiplatelet therapy, DuoPlavin should be discontinued 7 days prior to surgery.
Slovenian: Če mora bolnik začasno prekiniti antiagregacijsko terapijo morate zdravilo DuoPlavin ukiniti 7 dni pred kirurškim posegom.
English: If acetylsalicylic acid is used by a woman attempting to conceive, or until the 24th amenorrhea week (5th month of pregnancy), the dose should be kept as low and duration of treatment as short as possible.
Slovenian: Če acetilsalicilno kislino uporablja ženska, ki poskuša zanositi, ali do 24. tedna amenoreje (5. meseca nosečnosti), mora biti odmerek čim manjši, zdravljenje pa čim kratkotrajnejše.
English: What DuoPlavin is and what it is used for
Slovenian: Kaj je zdravilo DuoPlavin in za kaj ga uporabljamo
English: If the use of DuoPlavin is discontinued, patients may benefit with continuation of one antiplatelet medicinal product.
Slovenian: V primeru prenehanja uporabe zdravila DuoPlavin lahko bolniku koristi nadaljevanje uporabe enega antiagregacijskega zdravila.
English: If you experience prolonged bleeding when taking DuoPlavin If you cut or injure yourself, it may take longer than usual for bleeding to stop.
Slovenian: Če doživite podaljšanje krvavitve v času jemanja zdravila DuoPlavin Če se urežete ali poškodujete, lahko traja dlje kot običajno, da se vam krvavitev ustavi.
English: A pharmacodynamic interaction between DuoPlavin and heparin is possible, leading to increased risk of bleeding.
Slovenian: Farmakodinamična interakcija med zdravilom DuoPlavin in heparinom je možna in vodi do povečanega tveganja za krvavitev.
English: Driving and using machines DuoPlavin should not affect your ability to drive or to use machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Zdravilo DuoPlavin ne bi smelo vplivati na vašo sposobnost za vožnjo ali upravljanje strojev.
English: • Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Slovenian: • preobčutljivosti za zdravilni učinkovini ali katero koli pomožno snov, navedeno v poglavju 6.1,
English: Other medicines and DuoPlavin
Slovenian: Druga zdravila in zdravilo DuoPlavin
English: What you need to know before you take DuoPlavin
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo DuoPlavin
English: DuoPlavin has no or negligible influence on the ability to drive and use machines.
Slovenian: Zdravilo DuoPlavin nima ali ima zanemarljiv vpliv na sposobnost za vožnjo in upravljanje strojev.
English: This randomized, open-label trial included ACS patients requiring PCI.
Slovenian: To randomizirano, odprto preskušanje je vključilo bolnike z AKS, ki so potrebovali PKI.
English: The population included 27.8% women, 58.4% patients ≥60 years (26% ≥70 years) and 54.5% patients who received fibrinolytics.
Slovenian: Populacijo bolnikov je sestavljalo 27,8 % žensk, 58,4 % bolnikov starost ≥ 60 let (26 % ≥ 70 let ) in 54,5 % bolnikov, ki so dobivali fibrinolitike.
English: This benefit was mostly driven by the statistically significant reduction in the incidence of MI [287 (4.6%) in the clopidogrel plus ASA group and 363 (5.8%) in the ASA group].
Slovenian: Ta korist je bila v glavnem zaradi statistično pomembnega zmanjšanja incidence MI [287 (4,6 %) v skupini, zdravljeni s klopidogrelom in ASA, in 363 (5,8 %) v skupini z ASA].
English: Apart from the specific medicinal product interaction information described above, interaction studies with DuoPlavin and some medicinal products commonly administered in patients with atherothrombotic disease have not been performed.
Slovenian: Razen navedenih informacij o specifičnih interakcijah z zdravili, študij o interakcijah zdravila DuoPlavin in nekaterih zdravil, ki jih pogosto uporabljajo bolniki z aterotrombotično boleznijo ni bilo.
English: It also contains: lactose and hydrogenated castor oil.
Slovenian: Vsebuje tudi laktozo in hidrogenirano ricinusovo olje.
English: Salicylic acid in DuoPlavin has a plasma half-life of approximately 2 hours.
Slovenian: Salicilna kislina iz zdravila DuoPlavin ima plazemski razpolovni čas približno 2 uri.
English: Until the 24th amenorrhea week (5th month of pregnancy), acetylsalicylic acid should not be given unless clearly necessary.
Slovenian: Do 24. tedna amenoreje (5. meseca nosečnost) se acetilsalicilne kisline ne sme uporabljati, če ni nujno potrebno.
English: If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking DuoPlavin.
Slovenian: Če ste noseči ali mislite, da ste noseči, morate o tem obvestiti zdravnika ali farmacevta, preden vzamete zdravilo DuoPlavin.
English: A patient with poor metaboliser status will possess two loss-offunction alleles as defined above.
Slovenian: Bolnik, ki je slab metabolizator, ima dva hipofunkcijska alela, kot je pojasnjeno zgoraj.
English: Breast-feeding should be discontinued during treatment with DuoPlavin.
Slovenian: Dojenje je med zdravljenjem z zdravilom DuoPlavin potrebno prekiniti.
English: DuoPlavin prolongs bleeding time and should be used with caution in patients who have lesions with a propensity to bleed (particularly gastrointestinal and intraocular).
Slovenian: Zdravilo DuoPlavin podaljša čas krvavitve in ga je potrebno previdno uporabljati pri bolnikih z lezijami, ki so nagnjene h krvavitvi (zlasti gastrointestinalne in intraokularne).
English: No clinical data on exposure to DuoPlavin during pregnancy are available.
Slovenian: Kliničnih podatkov o izpostavljenosti zdravilu DuoPlavin v nosečnosti ni na voljo.
English: • the mother and the neonate, at the end of pregnancy, to: - possible prolongation of bleeding time, an anti-aggregating effect which may occur even at very low doses; - inhibition of uterine contractions resulting in delayed or prolonged labour.
Slovenian: • mater in novorojenčka na koncu nosečnosti: - možnemu podaljšanju časa krvavitve, antiagregacijskemu učinku, ki se lahko pojavi celo po zelo majhnih odmerkih, - zavrtju krčenja maternice in zaradi tega odloženemu ali podaljšanemu porodu.
English: As no clinical data on exposure to clopidogrel during pregnancy are available, it is preferable not to use clopidogrel during pregnancy as a precautionary measure.
Slovenian: Ker kliničnih podatkov o izpostavljenosti klopidogrelu med nosečnostjo ni, je kot previdnostni ukrep zaželeno, da se klopidogrela med nosečnostjo ne uporabljate.
English: Therefore, this combination should be used with caution in patients taking low dose ASA for cardioprotection .
Slovenian: Zato je to kombinacijo treba uporabljati previdno pri bolnikih, ki jemljejo nizke odmerke acetilsalicilne kisline za zaščito srca.
English: Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy.
Slovenian: Podatki epidemioloških študij kažejo večje tveganje spontanih splavov, malformacij srca in gastroshize po uporabo zaviralcev sinteze prostaglandinov v zgodnji nosečnosti.
English: Adverse reactions that occurred with clopidogrel alone, with ASA alone or with clopidogrel in combination with ASA either during clinical studies or that were spontaneously reported are presented in the table below.
Slovenian: Neželeni učinki, zabeleženi samo s klopidogrelom, samo z ASA ali s klopidogrelom v kombinaciji z ASA v kliničnih študijah ali opisani spontano, so našteti v spodnji tabeli.
English: - if you have any stomach or abdominal pain or bleeding in the stomach or bowels (red stools or black stools).
Slovenian: - če imate bolečine v želodcu ali trebuhu ali krvavitev v želodec ali črevo (rdeče blato ali črno blato).
English: • Severe renal impairment (creatinine clearance <30 ml/min).
Slovenian: • pri bolnikih s hudo okvaro ledvic (očistek kreatinina <30 ml/min),
English: 1, rue de la Vierge, Ambarès & Lagrave, F-33565 Carbon Blanc cedex, France
Slovenian: 1, Rue de la Vierge, Ambarès & Lagrave, F-33565 Carbon Blanc cedex, Francija
English: For the treatment of this condition your doctor may have placed a stent in the blocked or narrowed artery to restore effective blood flow.
Slovenian: Morda vam je zdravnik za zdravljenje vaše bolezni v zamašeno ali zoženo arterijo namestil žilno opornico ("stent"), da bi obnovil ustrezen pretok krvi.
English: DuoPlavin is indicated for the secondary prevention of atherothrombotic events in adult patients already taking both clopidogrel and acetylsalicylic acid (ASA).
Slovenian: Zdravilo DuoPlavin je indicirano za sekundarno preprečevanje aterotrombotičnih dogodkov pri odraslih bolnikih, ki že jemljejo klopidogrel in acetilsalicilno kislino (ASA).
English: Store below 25C.
Slovenian: Shranjujte pri temperaturi do 25C.
English: Minor GI symptoms, such as dyspepsia, are common and can occur anytime during therapy.
Slovenian: Manj izraziti gastrointestinalni simptomi npr. dispepsija, so sicer pogosti in se lahko pojavijo kadarkoli med zdravljenjem.
English: Thrombotic Thrombocytopenic Purpura (TTP) has been reported very rarely following the use of clopidogrel, sometimes after a short exposure.
Slovenian: Zelo redko so po uporabi klopidogrela poročali o trombotični trombocitopenični purpuri (TTP), ki se je včasih pojavila že po kratki izpostavljenosti.
English: DuoPlavin is taken by adults to prevent blood clots forming in hardened arteries which can lead to atherothrombotic events (such as stroke, heart attack, or death).
Slovenian: Zdravilo DuoPlavin jemljejo odrasli za preprečevanje nastanka krvnih strdkov v otrdelih krvnih žilah, ki lahko vodi do aterotrombotičnih dogodkov (kot so kap, srčni napad ali smrt).
English: Thus, beyond 3 months of treatment, the benefit observed in the clopidogrel plus ASA group was not further increased, whereas the risk of haemorrhage persisted (see section 4.4).
Slovenian: Tako se pri zdravljenju več kot 3 mesece opažena korist v skupini, ki je prejemala klopidogrel in ASA, ni nadalje povečevala, medtem ko je tveganje za krvavitev ostala (glejte poglavje 4.4).
English: • if you are allergic to other products called non-steroidal anti-inflammatory products usually used to treat painful and/or inflammatory conditions of muscles or joints.
Slovenian: • če ste alergični na druga zdravila, t. i. nesteroidna protivnetna zdravila, ki jih ponavadi uporabljamo za zdravljenje bolečih in/ali vnetja mišic ali sklepov,
English: • if you are allergic to clopidogrel, acetylsalicylic acid (ASA) or any of the other ingredients of this medicine (listed in section 6).
Slovenian: • če ste alergični na klopidogrel, acetilsalicilno kislino (ASA) ali katero koli sestavino tega zdravila
English: Do not take DuoPlavin during third trimester of pregnancy.
Slovenian: Zdravila DuoPlavin ne smete jemati v tretjem trimesečju nosečnosti.
English: The safety and efficacy of clopidogrel plus ASA have been evaluated in three double-blind studies involving over 61,900 patients: the CURE, CLARITY and COMMIT studies, comparing clopidogrel plus ASA to ASA alone, both treatments given in combination with other standard therapy.
Slovenian: Varnost in učinkovitost klopidogrela in ASA so vrednotili v treh dvojno slepih raziskavah, v katere je bilo vključenih več kot 61.900 bolnikov: CURE, CLARITY in COMMIT, ki so primerjale kombinacijo klopidogrela in ASA s samo ASA; oboje so bolniki dobivali v kombinaciji z drugo standardno terapijo.
English: Due to the presence of ASA, methotrexate used at doses higher than 20 mg/week should be used with caution with DuoPlavin as it can inhibit renal clearance of methotrexate, which may lead to bone marrow toxicity.
Slovenian: Zaradi vsebnosti ASA je med sočasno uporabo metotreksata, ki se uporablja v odmerku višjem od 20 mg/teden, z zdravilom DuoPlavin potrebna previdnost, ker lahko zavre ledvični očistek metotreksata in tako povzroči toksične učinke na kostni mozeg.
English: Clopidogrel plus ASA significantly reduced the relative risk of death from any cause by 7% (p = 0.029), and the relative risk of the combination of re-infarction, stroke or death by 9% (p = 0.002), representing an absolute reduction of 0.5% and 0.9%, respectively.
Slovenian: Klopidogrel in ASA sta pomembno zmanjšala relativno tveganje za smrt zaradi kateregakoli vzroka za 7 % (p=0,029) in relativno tveganje za ponovni infarkt, kap ali smrt za 9 % (p=0,002), kar je predstavljalo absolutno zmanjšanje za 0,5 % oziroma 0,9 %.
English: The primary endpoint was the occurrence of the composite of an occluded infarct-related artery on the predischarge angiogram, or death or recurrent MI before coronary angiography.
Slovenian: Primarni opazovani dogodki so bili navzočnost zamašene arterija (povezane z infarktom) na angiogramu pred odpustom ali smrt ali ponovni miokardni infarkt pred koronarno angiografijo.
English: You have been prescribed DuoPlavin in place of the two separate medicines, clopidogrel and ASA, to help prevent blood clots because you have experienced a severe type of chest pain known as ‘unstable angina' or heart attack (myocardial infarction).
Slovenian: Zdravnik vam je predpisal zdravilo DuoPlavin namesto dveh posameznih zdravil klopidogrela in ASA, kot pomoč za preprečevanje nastanka krvnih strdkov, ker ste imeli hudo obliko bolečine v prsih, znano kot "nestabilna angina pektoris", ali ker ste imeli srčni infarkt (miokardni infarkt).
English: If you become pregnant while taking DuoPlavin, consult your doctor immediately as it is recommended not to take DuoPlavin while you are pregnant.
Slovenian: Če med zdravljenjem z zdravilom DuoPlavin zanosite, se takoj posvetujte z zdravnikom, kajti jemanje zdravila DuoPlavin med nosečnostjo ni priporočljivo.
English: Due to the presence of ASA, DuoPlavin is contraindicated during the third trimester of pregnancy.
Slovenian: Zaradi vsebnosti ASA je zdravilo DuoPlavin kontraindicirano v tretjem trimesečju nosečnosti.
English: • the foetus to: - cardiopulmonary toxicity (with premature closure of the ductus arteriosus and pulmonary hypertension); - renal dysfunction, which may progress to renal failure with oligo-hydroamniosis;
Slovenian: • plod: - kardiopulmonalnim toksičnim učinkom (s prezgodnjim zaprtjem arterioznega duktusa in pljučno hipertenzijo), - motenemu delovanju ledvic, ki lahko napreduje v odpoved ledvic in oligohidramnij,
English: If you take more DuoPlavin than you should
Slovenian: Če ste vzeli večji odmerek zdravila DuoPlavin, kot bi smeli:
English: The use of clopidogrel in CURE was associated with a decrease in the need for thrombolytic therapy (RRR = 43.3%; CI: 24.3%, 57.5%) and GPIIb/IIIa inhibitors (RRR = 18.2%; CI: 6.5%, 28.3%).
Slovenian: Uporaba klopidogrela v CURE je bila povezana z zmanjšano potrebo po zdravljenju s trombolitiki (zmanjšanje RT= 43,3 %; IZ: 24,3 %, 57,5 %) in inhibitorji glikoproteinov IIb/IIIa (zmanjšanje RT =18,2 %; IZ: 6,5 %, 28,3 %).
English: What DuoPlavin is and what it is used for What you need to know before you take DuoPlavin How to take DuoPlavin
Slovenian: Kaj je zdravilo DuoPlavin in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo DuoPlavin Kako jemati zdravilo DuoPlavin Možni neželeni učinki
English: The recommended dose is one tablet of DuoPlavin per day to be taken orally with a glass of water, with or without food.
Slovenian: Priporočeni odmerek je ena tableta zdravila DuoPlavin na dan. Tableto vzemite s kozarcem vode.
English: Uncommon side effects (may affect up to 1 in 100 people):
Slovenian: Občasni neželeni učinki (pojavijo se lahko pri največ 1od 100 bolnikov):
English: For the 14, 28 and 84 tablets pack sizes you can check the day on which you last took a tablet of DuoPlavin by referring to the calendar printed on the blister.
Slovenian: Na koledarčku, ki je natisnjen na pretisnem omotu pakiranj po 14, 28 in 84 tablet, lahko preverite dan, ko ste nazadnje vzeli tableto zdravila DuoPlavin.
English: A number of other clinical studies have been conducted with clopidogrel and other concomitant medicinal products to investigate the potential for pharmacodynamic and pharmacokinetic (PK) interactions.
Slovenian: Druga zdravila: Številne druge klinične študije so izvedli s klopidogrelom in drugimi sočasno danimi zdravili, da bi proučili potencial za farmakodinamične in farmakokinetične interakcije.
English: After the 300 mg/75 mg dose regimen, antiplatelet responses were decreased in the poor metabolisers with mean IPA (5 μM ADP) of 24% (24 hours) and 37% (Day 5) as compared to IPA of 39% (24 hours) and 58% (Day 5) in the extensive metabolisers and 37% (24 hours) and 60% (Day 5) in the intermediate metabolisers.
Slovenian: Po odmerni shemi 300 mg/75 mg se je antiagregacijski odziv pri slabih metabolizatorjih zmanjšal: povprečno IPA (5 µM ADP) je bilo 24 % (24 ur) in 37 % (5. dan) v primerjavi z 39 % (24 ur) in 58 % (5. dan) pri dobrih metabolizatorjih ter 37 % (24 ur) in 60 % (5. dan) pri srednjih metabolizatorjih.
English: Kounis syndrome (vasospastic allergic angina / allergic myocardial infarction) in the context of a hypersensitivity reaction due to acetylsalicylic acid* or clopidogrel**
Slovenian: Kounisov sindrom (vazospastična alergijska angina / alergijski miokardni infarkt) v okviru preobčutljivostne reakcije zaradi acetilsalicilne kisline* ali klopidogrela**
English: Intracranial bleeding (some cases were reported with fatal outcome, especially in elderly), headache, paraesthesia, dizziness
Slovenian: Intrakranialna krvavitev (opisani so primeri s smrtnim izidom, zlasti pri starejših), glavobol, parestezije, omotica
English: Sanofi Winthrop Industrie 1 rue de la Vierge Ambarès et Lagrave F-33565 Carbon Blanc Cedex France
Slovenian: Sanofi Winthrop Industrie 1, Rue de la Vierge Ambarès et Lagrave F-33565 Carbon Blanc cedex Francija
English: (See section 4.5.)
Slovenian: (navedeno v poglavju 6),
English: Therefore DuoPlavin should be used with caution in these patients.
Slovenian: Zato je pri uporabi zdravila DuoPlavin pri the bolnikih potrebna previdnost.
English: In patients with non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction): The optimal duration of treatment has not been formally established.
Slovenian: Pri bolnikih z akutnim koronarnim sindromom brez elevacije ST spojnice (nestabilna angina ali miokardni infarkt brez Q zobca): optimalno trajanje zdravljenja ni bilo formalno ugotovljeno.
English: TOPIC (Timing Of Platelet Inhibition after acute Coronary syndrome)
Slovenian: Študija TOPIC (Tempiranje zavrtja trombocitov po akutnem koronarnem sindromu)
English: Serious haemorrhage, haemorrhage of operative wound, vasculitis (including Henoch-Schönlein purpura*), hypotension
Slovenian: Resne krvavitve, krvavitev operacijske rane, vaskulitis (vključno s HenochSchönleinovo purpuro *), hipotenzija
English: 5 How to store DuoPlavin Contents of the pack and other information
Slovenian: Shranjevanje zdravila DuoPlavin Vsebina pakiranja in dodatne informacije
English: It is unknown whether ASA dose in DuoPlavin alters fertility.
Slovenian: Ni znano, ali ASA v zdravilu DuoPlavin vpliva na plodnost.
English: Acute liver failure, liver injury, mainly hepatocellular*, hepatitis, elevation of hepatic enzymes*, abnormal liver function test, chronic hepatitis*
Slovenian: Akutna odpoved jeter, poškodba jeter, predvsem hepatocelularna*, hepatitis, zvišane vrednosti jetrnih encimov*, nenormalni testi jetrne funkcije, kronični hepatitis*