FrancophonIA/ELRC3.0 huggingface dataset:
English: Secondary test parameters included symptoms of vaginal atrophy and vaginal pH. With regard to the VMI, Linoladiol N was statistically significantly superior to placebo (mean VMI Linoladiol N group: at baseline 24.47%, on day 31, 64.23%; placebo group: baseline 32.01%, day 31 37.17%).
Croatian: Vezano uz VMI, Linoladiol N je bio statistički značajno nadmoćniji u odnosu na placebo (srednji VMI za grupu koja je primala Linoladiol N: u osnovici 24,47%, na dan 31., 64,23%; placebo grupa: osnovica 32,01%, dan 31., 37,17%).
English: Taking into account baseline corrected values, Cmax and Caverage in the 24 h interval after drug administration were 175 pmol/l and 55 pmol/l, respectively, regarding estradiol vaginal tablets 25 mcg, and 331 pmol/l and 120 pmol/l, respectively, regarding Linoladiol N.
Croatian: Uzimajući u obzir ispravljene vrijednosti za osnovnu vrijednost, Cmax i Caverage u intervalu od 24 sata nakon primjene lijeka iznosili su 175 pmol/l odnosno 55 pmol/l s obzirom na vaginalne tablete koje sadrže estradiol od 25 mcg, 331 pmol/l odnosno 120 pmol/l vezano uz Linoladiol N.
English: Despite any limitations of historical comparisons with other locally applied medicinal products, it can be concluded that exposure to estradiol after administration of Linoladiol N is considerably higher than after administration of other lower dosed estradiol products for topical intravaginal therapy.
Croatian: Usprkos ograničenjima povijesnih usporedbi s drugim lokalno primijenjenim lijekovima, može se zaključiti da je izlaganje estradiolu nakon primjene lijeka Linoladiol N značajno veće u odnosu na izlaganje nakon primjene drugih lijekova koji sadrže manje doze estradiola za topikalnu intravaginalnu terapiju.
English: Based on the higher dose and substantial systemic estradiol exposure this product is more comparable to systemic HRT products from a safety point of view.
Croatian: Na temelju većih doza i značajnog izlaganja estradiolu, ovaj je lijek sa stajališta sigurne primjene više usporediv sa sistemskim lijekovima za HRB.
English: 0.005 % w/w estradiol/0.4 % w/w prednisolone containing medicinal products for topical use (Linoladiol HN)
Croatian: Lijekovi koji sadrže 0,005 % w/w estradiola/0,4 % w/w prednizolona za topikalnu primjenu (Linoladiol HN)
English: • For the 0.01% w/w estradiol containing medicinal products for topical use the Committee considered that in view of the currently available data, the benefit-risk balance is favourable in the currently authorised indication, subject to restrictions, warnings and other changes to the product information, as well as further risk minimisation measures agreed.
Croatian: • je u slučaju lijekova koji sadrže 0,01% w/w estradiola za topikalnu primjenu, Povjerenstvo zaključilo da je u svjetlu trenutno dostupnih podataka omjer koristi i rizika povoljan u trenutno odobrenim indikacijama, što je predmetom ograničenja, upozorenja i drugih promjena u informacijama o proizvodu, kao i usuglašenih daljnjih mjera za smanjivanje rizika.
English: An increase in oestrogen-related risk with recurrent use of this product cannot be ruled out.
Croatian: Ne može se isključiti rizik povezan s estrogenom u slučaju rekurentne primjene ovog lijeka.
English: Based on the totality of the data available on the safety and the efficacy of 0.01% w/w estradiol containing medicinal products to-date the CHMP confirmed that the benefit-risk balance remains favourable subject to the restrictions, warnings, changes to the product information, and risk minimisation measures agreed.
Croatian: Na temelju ukupnih podataka dostupnih o sigurnosti i djelotvornosti lijekova koji sadrže 0,01% estradiola do danas, CHMP potvrdio je da je omjer koristi i rizika ostaje povoljan i predmetom je usuglašenih ograničenja, upozorenja, promjena u informacijama o proizvodu i mjerama smanjivanja rizika.
English: The Committee concluded that the benefit-risk balance of 0.005 % w/w estradiol, 0.4 % w/w prednisolone containing medicinal products for topical use for the initial short-term external treatment of acute, mild, inflamed, burning and itching skin diseases of the external female genital area in postmenopausal patients, for which weak-acting corticosteroids and low-dose estradiol are indicated remains positive subject to the restrictions, warnings, changes to the product information agreed.
Croatian: Povjerenstvo je zaključilo da omjer koristi i rizika lijekova koji sadrže 0,005 % w/w estradiola, 0,4 % w/w prednizolona za topikalnu primjenu za početno kratkoročno vanjsko liječenje akutnih, blagih, upalnih kožnih bolesti praćenih osjećajem pečenja i svrbljenja vanjskih ženskih genitalnih područja u bolesnika u postmenopauzi, za koje su indicirani slabodjelujući kortikosteroidi i niske doze estradiola, ostaje pozitivan i predmetom je usuglašenih ograničenja, upozorenja, promjena u informacijama o proizvodu.
English: Of the three comparators (vaginal tablets 10 and 25 mcg and vaginal ring) discussed estradiol vaginal tablets 25 mcg is associated with the highest systemic exposure to estradiol and was compared to Linoladiol N. After a single dose of estradiol vaginal tablets 25 mcg, Cmax without baseline correction was 206 pmol/l, while Caverage without baseline correction during the first 24 h was 86 pmol/l based on the studies by Notelovitz (2002) and Nilsson and Heimer (1992).
Croatian: Nakon jedne doze vaginalnih tableta koje sadrže 25 mcg estradiola, Cmax bez ispravka osnovice bio je 206 pmol/l, dok je Caverage bez ispravka osnovice tijekom prva 24 sata bio je 86 pmol/l na temelju ispitivanja provedenog od strane Notelovitza (2002.), te Nilssona i Heimera (1992.).
English: information on supervision and appropriate warnings on e.g. endometrial hyperplasia and carcinoma, breast and ovarian cancer, need to be reflected in the appropriate section of the product information.
Croatian: Stoga, mišljenje je CHMP-a da uzimajući u obzir potencijalne rizike povezane sa svim liječenjima HRB-a, informacije o nadzoru i odgovarajuća upozorenja o primjerice endometrijalnoj hiperplaziji i karcinomu, raku doji i jajnika trebaju biti navedene u odgovarajućem poglavlju informacija o proizvodu.
English: • The Committee, in order to ensure that the 0.01% w/w estradiol containing medicinal products for topical use are not used for periods longer than 4 weeks, imposed the withdrawal of pack size of 100 g in all EU Members States where the products are authorised.
Croatian: • je Povjerenstvo nametnulo povlačenje pakiranja od 100g u svim državama članicama u kojima je proizvod odobren, kako bi se osiguralo da se lijekovi koji sadrže 0,01% w/w estradiola za topikalnu primjenu koriste samo za razdoblje od 4 tjedna.
English: The Committee concluded that the benefit-risk balance of 0.01% w/w estradiol containing medicinal products for the short-term external treatment of vaginal atrophy in postmenopausal patients when at least one topical oestrogen treatment has failed remains positive subject to the restrictions, warnings, changes to the product information agreed.
Croatian: Povjerenstvo je zaključilo da omjer koristi i rizika lijekova koji sadrže 0,01% w/w estradiola za kratkoročno vanjsko liječenje vaginalne atrofije u bolesnika u postmenopauzi u slučaju kada je najmanje jedno liječenje topikalnim estrogenom bilo neuspješno ostaje pozitivan i predmetom je usuglašenih ograničenja, upozorenja, promjena u informacijama o proizvodu.
English: In this study, mean estradiol serum concentrations at baseline and at day 31 (i.e. about 36 h after administration of study medication on day 29) were 6.4 pg/ml and 15.1 pg/ml, respectively, in the Linoladiol N group and 4.4 pg/ml and 6.2 pg/ml, respectively, in the placebo group.
Croatian: U ovom ispitivanju, srednje koncentracije estradiola u serumu u osnovnoj vrijednosti i u 31. danu (odnosno otprilike 36 sati nakon primjene ispitivanog lijeka na 29. dan) iznosile su 6,4 pg/ml odnosno
English: Clarification as to the nature of the active substance, estradiol, as the most potent oestrogen and the potential effect on the skin and genetic information were also reflected in the product information, in line with current scientific knowledge.
Croatian: U skladu s aktualnim znanstvenim znanjem, u informacijama o proizvodu navedeno je i pojašnjenje vezano uz prirodu djelatne tvari, estradiola, kao najpotentnijeg estrogena, te potencijalno djelovanje na kožu i genetske informacije.
English: The Committee, as a consequence, concluded that the benefit-risk balance of the 0.01% w/w estradiol containing medicinal products for topical use as well as the 0.005 % w/w estradiol and 0.4 % w/w prednisolone containing medicinal products for topical use remains favourable subject to variation to the term of the marketing authorisation consisting of restrictions, warnings, and other changes to the product information, as well as the risk minimisation measures agreed, as applicable.
Croatian: Slijedom navedenog, Povjerenstvo je zaključilo da omjer koristi i rizika lijekova koji sadrže 0,01% w/w estradiola za topikalnu primjenu kao i lijekova koji sadrže 0,005 % w/w estradiola i 0,4 % w/w prednizolona za topikalnu primjenu ostaje povoljan, i prema tome predmetom je izmjena u uvjetima odobrenja za stavljanje lijeka u promet koji se sastoje od ograničenja, upozorenja i drugih izmjena u informacijama o proizvodu, kao i mjerama smanjivanja rizika koje su usuglašene.
English: The CHMP noted that the pharmacokinetic data demonstrate that estradiol is absorbed after vaginal application of the Linoladiol N. Systemic effects can be expected as the estradiol levels are increased above postmenopausal levels which range from 10-20 pg/ml.1
Croatian: Sistemsko djelovanje može se očekivati budući da su razine estradiola povećane iznad postmenopauzalnih razina čiji raspon iznosi od 10 do 20 pg/ml.1
English: Despite any limitations due to the historical comparisons, it can be concluded that the systemic exposure to estradiol observed for
Croatian: Usprkos bilo kakvim ograničenjima uslijed povijesnih usporedbi, može se zaključiti da je sistemsko izlaganje estradiolu uočeno za Linoladiol N veće od onog uočenog s drugim lijekovima predviđenima za topikalnu vaginalnu primjenu, koji sadrže estradiol.
English: See section 6.6.
Croatian: Vidi odjeljak 6.6.
English: This is not a sign of intoxication and disappears within some minutes without treatment.
Croatian: To nije znak intoksikacije i nestaje u roku od nekoliko minuta bez liječenja.
English: This product is highly flammable.
Croatian: Ovaj proizvod je vrlo zapaljiv.
English: All signs are generally reversible following supportive treatment.
Croatian: Svi znakovi su općenito reverzibilni uz potpornu terapiju.
English: Date of latest renewal: 07/01/2016.
Croatian: Datum zadnjeg produženja: 07/01/2016.
English: These effects will usually resolve without treatment.
Croatian: Ovi učinci obično nestaju bez liječenja.
English: The appropriate combination of pipettes should be used
Croatian: Treba upotrijebiti odgovarajuću kombinaciju pipeta
English: Used pipettes should be disposed of immediately.
Croatian: Korištene pipete treba odmah ukloniti.
English: ATCvet code: QP53AX27.
Croatian: ATCvet kod: QP53AX27.
English: This results in a rapid cessation of feeding within 0 to 4 hours after treatment followed by cessation of egg laying (oviposition), paralysis and death occurring within 4 to 48 hours.
Croatian: To rezultira brzim prestankom hranjenja unutar 4 sata nakon tretmana što prati prestanak polaganja jaja (ovipozicija), paraliza i smrt unutar 4 do 48 sati.
English: Open one sachet and remove the pipette.
Croatian: Otvoriti jednu vrećicu i izvaditi pipetu.
English: Date of first authorisation: 18/02/2011.
Croatian: Datum prvog odobrenja: 18/02/2011.
English: Interaction with other medicinal products and other forms of interaction:
Croatian: Interakcija s drugim medicinskim proizvodima i ostali oblici interakcije:
English: These measures should help to protect the environment.
Croatian: Ove mjere pomažu zaštiti okoliša.
English: Do not eat, drink or smoke while handling the veterinary medicinal product.
Croatian: Nemojte jesti, piti ili pušiti dok rukuje veterinarsko medicinskim proizvodom.
English: A clear, colourless to yellow solution.
Croatian: Bistra, bezbojna do žuta otopina.
English: If it occurs, the eyes should be rinsed slowly and gently with water.
Croatian: Ukoliko se pojavi, oči treba polako i nježno ispirati s vodom.
English: • avoid contact with eyes, as the product may cause moderate eye irritation.
Croatian: • izbjegavati dodir s očima jer proizvod može uzrokovati iritaciju oka.
English: Local and/or systemic reactions have been observed in some people after exposure.
Croatian: Nakon izlaganja lokalne i/ili sustavne reakcije su uočene kod nekih ljudi.
English: Step 2: Part the hair until the skin is visible.
Croatian: Korak 2: Razdijelite dlaku do vidljive kože.
English: Hold the pipette in an upright position away from your face.
Croatian: Držite pipetu u uspravnom položaju, dalje od lica.
English: Shelf life of the veterinary medicinal product as packaged for sale: 4 years.
Croatian: Rok valjanosti veterinarsko-medicinskih proizvoda kada je zapakiran za prodaju: 4 godine.
English: A dry white residue may be also observed.
Croatian: Može se javiti suhi bijeli talog.
English: Intervet Productions S.A. Rue de Lyons 27460 Igoville France
Croatian: Intervet Productions S.A. Rue de Lyons 27460 Igoville Francuska
English: Absorption through the skin also occurs, but this systemic absorption is partial and not relevant for the clinical efficacy.
Croatian: Javlja se i apsorpcija putem kože, ali je ona samo djelomična i nije relevantna za kliničku djelotvornost.
English: Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Croatian: Svaki neupotrebljeni veterinarsko-medicinski proizvod ili otpadni materijal dobiven primjenom tih veterinarsko-medicinskih proizvoda treba odlagati u skladu s lokalnim propisima.
English: • administer the product in a well-ventilated area;
Croatian: • primjenjivati proizvod u dobro prozračenim prostorima,
English: This veterinary medicinal product does not require any special temperature storage conditions.
Croatian: Ovaj veterinarsko-medicinski proizvod ne zahtijeva nikakve posebne temperaturne uvjete skladištenja.
English: The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
Croatian: Veterinarsko-medicinski proizvod može se koristiti kao dio strategije za liječenje alergijskih dermatitisa uzrokovanih buhama (FAD).
English: Ethyl acetoacetate Isopropyl alcohol.
Croatian: Etilni acetoacetat Izopropilni alkohol
English: The bioactivated metabolite acts as a voltage-dependent sodium channel antagonist in insects, by blocking the sodium channels that regulate the flow of sodium ions in the insect's nervous system.
Croatian: Bioaktivirani metabolit djeluje kao naponski osjetljiv antagonist natrijevih kanala insekta, blokirajući natrijeve kanaliće koji reguliraju protok natrijevih iona unutar živčanog sustava insekta.
English: Cats > 4 kg
Croatian: Mačke > 4 kg
English: Consult a veterinarian if you intend to use the product on dogs with other products or medication.
Croatian: Konzultirajte veterinara ako planirate upotrijebiti proizvod na psu zajedno s drugim proizvodom.
English: One pipette of Activyl delivers:
Croatian: Jedna pipeta Activyl sadrži:
English: Do not administer orally or via any other route.
Croatian: Ne upotrebljavati oralno ili na bilo koji drugi način.
English: In larger dogs, the entire contents of the pipette(s) should be applied evenly to 2-4 spots along the backline from the shoulder to the base of the tail.
Croatian: Kod većih pasa, cijeli sadržaj pipete (i) treba ravnomjerno nanijeti na 2 - 4 mjesta, na različitim mjestima duž leđne linije od ramena do baze repa.
English: If you notice any serious effects or other effects not mentioned in this package leaflet, please inform your veterinary surgeon.
Croatian: Ako zamijetite ozbiljne nuspojave ili druge nuspojave koje nisu opisane u uputi o VMP, molimo javite veterinaru.
English: Step 1: The cat should be standing for easy application.
Croatian: Korak 1: Mačka treba stajati radi lakše primjene.
English: Ask your veterinary surgeon how to dispose of medicines no longer required.
Croatian: Pitajte svoga veterinara kako zbrinuti proizvod koji više neće biti upotrebljen.
English: Indoxacarb is an ectoparasiticide belonging to the oxadiazine chemical family.
Croatian: Indoksakarb je ektoparaziticid koji pripada kemijskoj grupi oksadiazina.
English: This is normal and will generally resolve within a couple of days after administration.
Croatian: To je normalno i obično će nestati nekoliko dana nakon aplikacije.
English: The pipette consists of a blister film (polypropylene/cyclic-olefin-copolymer/polypropylene) and a foil lidstock (aluminium/polypropylene co-extruded) sealed into aluminium sachets.
Croatian: Pipeta se sastoji od blistera (polipropilen/ciklički-olefin-kopolimera/polipropilen) i folije (lidstock), (aluminij/polipropilen ko-ekstrudirane) zapečaćene u aluminijske vrećice.
English: Ensure that animals do not groom each other immediately following treatment.
Croatian: Osigurati da životinje međusobno ne dolaze u kontakt odmah nakon tretmana.
English: One ml contains 195 mg indoxacarb.
Croatian: Jedan ml sadržava 195 mg indoksakarba.
English: Following a single spot-on application of the product, indoxacarb can still be detected in both skin and hair coat after 4 weeks post-treatment.
Croatian: Nakon jedne primjene proizvoda, indoksakarb se može otkriti na koži i dlaci i 4 tjedna nakon tretmana.
English: • on the day of treatment, children must not handle treated animals and the animals should not be permitted to sleep with their owners, especially children;
Croatian: • na dan tretiranje djeca ne smiju dirati tretitane životinje i ne smije im se dozvoliti spavanje s vlasnicima, osobito ne s djecom;
English: Keep out of the sight and reach of children.
Croatian: Držati dalje od pogleda i dosega djece.
English: Squeeze the pipette firmly and apply the entire contents directly to the skin.
Croatian: Stisnite čvrsto pipetu i primijenite ukupan sadržaj izravno na kožu.
English: In clinical studies, Activyl was co-administered with deltamethrin collars impregnated with up to 4% deltamethrin without evidence of associated adverse reactions.
Croatian: U kliničkim ispitivanjima, Activyl se davao s deltametrin ogrlicama impregniranim s 4% deltametrina bez vidljivih znakova nuspojava.
English: Step 1: The dog should be standing for easy application.
Croatian: Korak 1: Pas treba stajati radi lakše primjene.
English: Following a single administration, the veterinary medicinal product will prevent further flea infestation for 4 weeks.
Croatian: Nakon jedne primjene veterinarsko medicinski proizvod će spriječiti daljnju infestaciju buhama kroz 4 tjedna.
English: Pregnancy: Do not use during pregnancy.
Croatian: Graviditet: Ne primjenjivati tijekom graviditeta.
English: No adverse effects were observed in dogs aged 8 weeks or older when administered 5 times the recommended dose on 8 occasions at 4 weeks intervals or administered 5 times the recommended dose on 6 occasions at 2 weeks intervals.
Croatian: Nisu zabilježene nuspojave kod pasa u dobi od 8 tjedana ili starijih, kod primjene preporučene doze, 5 puta u 8 navrata, u intervalima od 4 tjedna ili kod primjene preporučene doze, 5 puta u 6 navrata, u intervalima od dva tjedna.
English: The major route of excretion is in faeces.
Croatian: Glavni put izlučivanja je izmetom.
English: To avoid adverse reactions:
Croatian: Radi izbjegavanja nuspojava:
English: A proper treatment of the pet´s environment by additional chemical or physical measures is recommended.
Croatian: Preporuča se odgovarajući tretman okoliša psa dodatnim kemijskim ili fizičkim mjerama.
English: Minimum of 25
Croatian: Male mačke najmanje 25
English: Apply to the skin only, at the base of the skull.
Croatian: Primijenite samo na kožu, na bazu lubanje.
English: The veterinary product should not be allowed to enter surface waters.
Croatian: Veterinarski proizvod ne smije doći u površinske vode.
English: The application of the veterinary medicinal product may produce a local, temporary oily appearance or hair clumping at the application site.
Croatian: Primjena veterinarsko medicinskog proizvoda može lokalno proizvesti, privremeni masni izgled dlake na mjestu primjene.
English: Also contains isopropyl alcohol 354 mg/ml.
Croatian: Također sadrži izopropilni alkohol 354 mg/ml.
English: Do not give the product by mouth or any other route.
Croatian: Ne upotrebljavati kroz usta ili na bilo koji drugi način.
English: Activyl should not enter water courses as this may be dangerous for fish and other aquatic organisms.
Croatian: Activyl ne smije doći u vodene tokove jer to može biti štetno za ribe i druge vodene organizme.
English: Isopropyl alcohol 354 mg/ml.
Croatian: Izopropilni alkohol 354 mg/ml.
English: Keep away from heat, sparks, open flame or other sources of ignition.
Croatian: Držati dalje od vrućine, iskre, otvorene vatre i drugih izvora paljenja.
English: Do not apply an excessive amount of solution at any one spot in order to prevent run-off.
Croatian: Ne nanositi pretjeranu količinu na bilo kojem mjestu koja bi mogla uzrokovati curenje.
English: It enters the insect primarily through ingestion but is also absorbed, to a lesser degree, through the insect cuticle.
Croatian: Aktivna tvar primarno ulazi probavom u tijelo insekta, ali također u manjem stupnju se apsorbira kroz kutikulu.
English: Marketing authorisation holder: Intervet International BV Wim de Körverstraat 35
Croatian: Nositelj odobrenja za stavljanje u promet: Intervet International BV Wim de Korverstraat 35
English: EU/02/10/118/003 EU/02/10/118/004 EU/02/10/118/005 EU/02/10/118/006 EU/02/10/118/007 EU/02/10/118/008 EU/02/10/118/009 EU/02/10/118/010 EU/02/10/118/015 EU/02/10/118/016 EU/02/10/118/017 EU/02/10/118/018 EU/02/10/118/019
Croatian: EU/02/10/118/001 EU/02/10/118/002 EU/02/10/118/003 EU/02/10/118/004 EU/02/10/118/005 EU/02/10/118/006 EU/02/10/118/007 EU/02/10/118/008 EU/02/10/118/009 EU/02/10/118/010 EU/02/10/118/015 EU/02/10/118/016 EU/02/10/118/017 EU/02/10/118/018 EU/02/10/118/019
English: In the mid-gut of susceptible insect species, the insect's enzymes remove the carbomethoxy group from parent indoxacarb, and convert it into its biologically active form.
Croatian: U srednjem crijevu osjetljivog insekta, enzimi uklanjaju karbometoksi grupu indoksikarb molekule i pretvaraju je u biološki aktivni oblik.
English: The product remains effective following shampoo treatment, water immersion (swimming, bathing) and exposure to sunlight.
Croatian: Proizvod ostaje djelotvoran nakon šamponiranja, utjecaja vode (kupanje, plivanje) i izloženosti suncu.
English: For cats: Veterinary medicinal product subject to prescription.
Croatian: Za mačke: Veterinarsko medicinski proizvod se izdaje na recept.
English: Correct application (see section 4.9) will minimise licking of the application site.
Croatian: Ispravna primjena (vidi odjeljak 4.9) će smanjiti lizanje na mjestu primjene.
English: Indoxacarb is a pro-drug that requires bioactivation by the insect enzymes to exert its pharmacodynamic effects.
Croatian: Indoksakarb je tvar koja svoju bioaktivaciju postiže enzimima insekta kako bi ostvarila farmakodinamički učinak.
English: One unit-dose pipette holds 0.51 ml or 1.03 ml spot-on solution.
Croatian: Jedna pipeta s jediničnom dozom sadrži 0,51 ml ili 1,03 ml spot on otopine.
English: In fleas, in addition to its adulticidal activity, indoxacarb activity on the developing larval stages in the immediate surroundings of the treated pet has been demonstrated.
Croatian: U buha, pored svoje adulticidne aktivnosti, indoksakarb se pokazao aktivan i protiv larvalnih stadija u neposrednoj okolini tretiranog ljubimca.
English: The veterinary product should not enter water courses.
Croatian: Veterinarski proizvod ne smije doći u vodene tokove.
English: One unit-dose pipette holds 0.51 ml, 0.77 ml, 1.54 ml, 3.08 ml or 4.62 ml spot-on solution.
Croatian: Jedna pipeta s jediničnom dozom sadržava 0,51 ml, 0,77 ml, 1,54 ml, 3,08 ml ili 4,62 ml otopine za nakapavanje.