FrancophonIA/ELRC3.0 huggingface dataset:
English: Fracture adverse events of long bones in the lower extremities were reported in approximately 24% (femur) and 14% (tibia) of zoledronic acid-treated patients versus 12% and 5% of pamidronate-treated patients with severe osteogenesis imperfecta, regardless of disease type and causality but overall incidence of fractures was comparable for the zoledronic acid and pamidronate-treated patients: 43% (32/74) versus 41% (31/76).
Slovenian: O zlomih dolgih kosti spodnjih okončin so pri bolnikih s hudo obliko osteogenesis imperfecta, ki so prejemali zoledronsko kislino, poročali v približno 24 % (zlom stegnenice) in v 14 % (zlom golenice) v primerjavi z enakovrednimi bolniki, ki so prejemali pamidronat, pri katerih so o zlomu stegnenice poročali v 12 %, o zlomu golenice pa v 5 %.
English: Placebo Zoledronic acid 4 mg
Slovenian: 4 mg placebo zoledronska kislina
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 °C - 8 °C, unless dilution has taken place in controlled and validated aseptic conditions.
Slovenian: se zdravilo ne uporabi takoj, je uporabnik odgovoren za trajanje in pogoje shranjevanja pred uporabo, kar ponavadi ne traja dalj kot 24 ur pri temperaturi 2 ºC do 8 ºC, razen če je redčenje potekalo v kontroliranih in validiranih aseptičnih pogojih.
English: - if you are allergic to zoledronic acid, another bisphosphonate (the group of substances to which
Slovenian: Zdravila Zoledronska kislina medac ne smete dobiti: - če dojite, - če ste alergični na zoledronsko kislino, kak drug difosfonat (skupina snovi, ki ji pripada zdravilo
English: Table 3: Efficacy results (prostate cancer patients receiving hormonal therapy) Any SRE (+TIH)
Slovenian: Preglednica 3: Rezultati učinkovitosti (bolniki z rakom prostate, ki so prejemali hormonsko zdravljenje)
English: - High blood pressure, shortness of breath, dizziness, sleep disturbances, taste disturbances,
Slovenian: - bolečina v prsih, - kožne reakcije (rdečina in otekanje) na mestu infuzije, izpuščaj, srbenje, - visok krvni tlak, zadihanost, omotičnost, motnje spanja, motnje okušanja, tresenje,
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 °C - 8 °C.
Slovenian: Če zdravstveni delavec raztopine ne uporabi takoj, je sam odgovoren za trajanje in pogoje shranjevanja pred uporabo, kar ponavadi ne traja dalj kot 24 ur pri temperaturi 2ºC
English: QUALITATIVE AND QUANTITATIVE COMPOSITION One bottle with 100 ml solution contains 4 mg zoledronic acid (as monohydrate).
Slovenian: Ena plastenka s 100 ml raztopine vsebuje 4 mg zoledronske kisline (v obliki monohidrata).
English: How Zoledronic acid medac is used
Slovenian: Kako se zdravilo Zoledronska kislina medac daje
English: - Weight increase.
Slovenian: - Navodilo shranite.
English: NAME OF THE MEDICINAL PRODUCT Zoledronic acid medac 4 mg/100 ml solution for infusion Zoledronic acid
Slovenian: Zoledronska kislina medac 4 mg/100 ml raztopina za infundiranje zoledronska kislina
English: You must not be given Zoledronic acid medac if you are breast-feeding.
Slovenian: Če dojite, vam ne smejo dati zdravila Zoledronska kislina medac.
English: NAME OF THE MEDICINAL PRODUCT Zoledronic acid medac 4 mg/100 ml solution for infusion
Slovenian: Zoledronska kislina medac 4 mg/100 ml raztopina za infundiranje
English: It is especially important that you tell your doctor if you are also taking: - Aminoglycosides (medicines used to treat severe infections), calcitonin (a type of medicine used to treat post-menopausal osteoporosis and hypercalcaemia), loop diuretics (a type of medicine to treat high blood pressure or oedema) or other calcium-lowering medicines, since the combination of these with bisphosphonates may cause the calcium level in the blood to become too low.
Slovenian: diuretike Henlejeve zanke (vrsta zdravila za zdravljenje visokega krvnega tlaka ali otekanja) ali druga zdravila, ki znižujejo koncentracijo kalcija, ker kombinacija le-teh z difosfonati lahko preveč zniža koncentracijo kalcija v krvi, - talidomid (zdravilo, ki ga uporabljamo pri zdravljenju določenih vrst krvnega raka, ki zajemajo kosti) ali druga zdravila, ki lahko škodujejo ledvicam,
English: • Zoledronic acid medac 4 mg/100 ml solution for infusion can be used immediately without further preparation for patients with normal renal function.
Slovenian: • Za bolnike z normalnim delovanjem ledvic je zdravilo Zoledronska kislina medac 4 mg/100 ml raztopina za infundiranje mogoče uporabiti takoj brez dodatne priprave.
English: You should not be given Zoledronic acid medac if you are pregnant.
Slovenian: Če ste noseči, vam ne bi smeli dati zdravila Zoledronska kislina medac.
English: Zoledronic acid medac must only be prescribed and administered to patients by healthcare professionals experienced in the administration of intravenous bisphosphonates.
Slovenian: Zdravilo Zoledronska kislina medac smejo predpisovati in dajati bolnikom samo zdravstveni delavci,
English: NAME OF THE MEDICINAL PRODUCT Zoledronic acid medac 4 mg/5 ml concentrate for solution for infusion
Slovenian: Zoledronska kislina medac 4 mg/5 ml koncentrat za raztopino za infundiranje
English: PHARMACEUTICAL FORM Solution for infusion Clear, colourless solution.
Slovenian: raztopina za infundiranje bistra in brezbarvna raztopina
English: 3.5 mg*
Slovenian: 4,0 mg 3,5 mg* 3,3 mg* 3,0 mg*
English: MARKETING AUTHORISATION NUMBER(S) EU/1/12/779/005
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/12/779/005
English: Cases of osteonecrosis of the jaw have been reported, predominantly in cancer patients treated with medicinal products that inhibit bone resorption, such as Zoledronic acid medac (see section 4.4).
Slovenian: Predvsem pri bolnikih z rakom, zdravljenih z zdravili, ki zavirajo resorpcijo kosti, kot je zdravilo
English: 1 bottle of 100 ml.
Slovenian: 1 steklenica s 100 ml. Del skupnega pakiranja.
English: Very common (may affect more than 1 in 10 people): - Low level of phosphate in the blood.
Slovenian: Zelo pogosti (pojavijo se lahko pri več kot 1 od 10 bolnikov):
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE(S) OF ADMINISTRATION Zoledronic acid medac 4 mg/5 ml sterile concentrate Intravenous use.
Slovenian: Zoledronska kislina medac 4 mg/5 ml sterilni koncentrat intravenska uporaba
English: Episcleritis
Slovenian: uveitis episkleritis
English: Table 3: Efficacy results (solid tumours other than breast or prostate cancer)
Slovenian: Preglednica 3: Rezultati učinkovitosti (čvrsti tumorji, razen raka dojke in prostate) kateri koli SRE (+TIH) zlomi*
English: NAME OF THE MEDICINAL PRODUCT Zoledronic acid medac 4 mg/5 ml concentrate for solution for infusion Zoledronic acid
Slovenian: Zoledronska kislina medac 4 mg/5 ml koncentrat za raztopino za infundiranje zoledronska kislina
English: Each vial contains 100 ml of solution
Slovenian: Ena viala vsebuje 100 ml koncentrata.
English: Uncommon: Very rare:
Slovenian: preobčutljivostna reakcija redki:
English: - Increased sweating.
Slovenian: - zvečanje telesne mase, - zvečano znojenje,
English: Additionally, there have been sporadic reports of osteonecrosis of other sites, including the hip and femur, reported predominantly in adult cancer patients treated with Zoledronic acid medac.
Slovenian: O teh primerih so poročali predvsem pri odraslih bolnikih z rakom, ki so se zdravili z zdravilom Zoledronska kislina medac.
English: Common: Uncommon:
Slovenian: konjunktivitis občasni:
English: MARKETING AUTHORISATION NUMBER(S) EU/1/12/779/002
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/12/779/002
English: Tell your doctor and dentist immediately if you experience such symptoms while being treated with Zoledronic acid medac or after stopping treatment.
Slovenian: Če pride do takih simptomov med zdravljenjem ali po prenehanju zdravljenja z zdravilom Zoledronska kislina medac, takoj obvestite svojega zdravnika in zobozdravnika.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING LABEL ON MULTIPACKS WITH 4 VIALS WRAPPED IN TRANSPARENT FOIL (INCLUDING BLUE BOX)
Slovenian: NALEPKA NA SKUPNEM PAKIRANJU S 4 VIALAMI, OVITIMI V PROZORNO FOLIJO (Z BLUE BOX)
English: LABEL ON MULTIPACKS WITH 10 VIALS WRAPPED IN TRANSPARENT FOIL (INCLUDING BLUE BOX)
Slovenian: NALEPKA NA SKUPNEM PAKIRANJU Z 10 VIALAMI, OVITIMI V PROZORNO FOLIJO (Z BLUE BOX)
English: This is because you may develop serum electrolyte abnormalities (e.g. abnormal levels of calcium, phosphorus and magnesium) and/or changes in kidney function, including severe kidney impairment.
Slovenian: Če ste prejeli večji odmerek zdravila Zoledronska kislina medac, kot bi smeli Če ste prejeli odmerek, ki je večji od priporočenega, vas mora zdravnik natančno nadzorovati, zato ker lahko pride do nepravilnosti elektrolitov v serumu (do nepravilnih koncentracij kalcija, fosforja in magnezija) in/ali do spremenjenega delovanja ledvic, vključno z ledvično odpovedjo.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/12/779/004
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/12/779/004
English: Uveitis
Slovenian: zmedenost
English: - Blurred vision, tearing of the eye, eye sensitivity to light.
Slovenian: - zamegljen vid, solzenje oči, občutljivost oči na svetlobo, - nenaden občutek hladu z izgubo zavesti, mlahavost ali kolaps (padec zaradi nenadnega znižanja krvnega tlaka),
English: Package leaflet: Information for the user Zoledronic acid medac 4 mg/100 ml solution for infusion Zoledronic acid
Slovenian: Navodilo za uporabo Zoledronska kislina medac 4 mg/100 ml raztopina za infundiranje zoledronska kislina
English: Grounds for the variation to the terms of the marketing authorisation(s)
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET Z ZDRAVILOM
English: Anaemia
Slovenian: pancitopenija
English: Package leaflet: Information for the user Zoledronic acid medac 4 mg/5 ml concentrate for solution for infusion Zoledronic acid
Slovenian: Navodilo za uporabo Zoledronska kislina medac 4 mg/5 ml koncentrat za raztopino za infundiranje zoledronska kislina
English: Zoledronic acid medac 4mg/100ml solution for infusion medac Gesellschaft für klinische Spezialpräparate mbH Theaterstr.
Slovenian: IZDELOVALCI, ODGOVORNI ZA SPROŠČANJE SERIJ Ime in naslov izdelovalcev, odgovornih za sproščanje serij Zoledronska kislina medac 4 mg/100 ml raztopina za infundiranje medac Gesellschaft für klinische Spezialpräparate mbH
English: SPECIAL STORAGE CONDITIONS Do not freeze.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE
English: In patients with bone metastases presenting with mild to moderate renal impairment prior to initiation of therapy, which is defined for this population as CLcr 30-60 ml/min, the following zoledronic acid dose is recommended (see also section 4.4):
Slovenian: (opredeljeno za to skupino bolnikov kot CLcr 30-60 ml/min), priporočajo naslednji odmerek zoledronske kisline (glejte tudi poglavje 4.4):
English: STATEMENT OF ACTIVE SUBSTANCE(S) One bottle contains 4 mg of zoledronic acid (as monohydrate).
Slovenian: Ena steklenica vsebuje 4 mg zoledronske kisline (v obliki monohidrata).
English: STATEMENT OF ACTIVE SUBSTANCE(S) One vial contains 4 mg of zoledronic acid (as monohydrate).
Slovenian: Ena viala vsebuje 4 mg zoledronske kisline (v obliki monohidrata).
English: How to prepare and administer Zoledronic acid medac
Slovenian: Kako zdravilo Zoledronska kislina medac pripravljate in dajete
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING BOTTLE LABEL
Slovenian: PODATKI NA STIČNI OZ. PRIMARNI OVOJNINI NALEPKA STEKLENICE
English: If you are given more Zoledronic acid medac than you should be If you have received doses higher than those recommended, you must be carefully monitored by your doctor.
Slovenian: Kaj morate vedeti, preden vam bodo dali zdravilo Zoledronska kislina medac Skrbno se ravnajte po vseh navodilih, ki vam jih je dal vaš zdravnik.
English: It is available as chewable tablets (2.5 mg/20 mg, 5 mg/40 mg and 10 mg/80 mg).
Slovenian: Na voljo je v obliki žvečljivih tablet (2,5 mg/20 mg, 5 mg/40 mg in 10 mg/80 mg).
English: The European Commission granted a marketing authorisation valid throughout the European Union, for Cardalis on 23 July 2012.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Cardalis, veljavno po vsej Evropski uniji, odobrila dne 23. julija 2012.
English: Other information about Cardalis:
Slovenian: Druge informacije o zdravilu Cardalis:
English: The tablets may either be mixed with a small amount of food offered to the dog just before the main meal, or with the meal itself.
Slovenian: Tablete se lahko primešajo majhni količini hrane, ki se psu ponudi tik pred glavnim obrokom, ali v sam obrok.
English: This is a type of heart disease where the heart cannot pump enough blood around the body.
Slovenian: To je vrsta srčnega obolenja, ko srce ne more načrpati dovolj krvi po vsem telesu.
English: It must not be used in dogs intended or used for breeding.
Slovenian: Ni ga dovoljeno uporabljati pri psih, ki so namenjeni ali se uporabljajo za vzrejo.
English: The main measure of effectiveness was good treatment compliance, which was defined as dogs consuming at least 90% of their tablets.
Slovenian: Glavno merilo učinkovitosti je bilo dobro sodelovanje pri zdravljenju, ki je bilo opredeljeno kot psi, ki so zaužili vsaj 90 % tablet.
English: People should wash their hands after handling the tablets.
Slovenian: Po dajanju tablet si je treba umiti roke.
English: The Committee for Medicinal Products for Veterinary Use (CVMP) concluded that the benefits of Cardalis exceed the risks and recommended that be given a marketing authorisation.
Slovenian: Odbor za zdravila za uporabo v veterinarski medicini (CVMP) je zaključil, da so koristi zdravila Cardalis večje od z njim povezanih tveganj, in priporočil, da se zanj odobri dovoljenje za promet.
English: The field study showed Cardalis to be voluntarily and fully consumed 92% of the time when offered with or without food and around 86% of dogs showed good compliance with treatment.
Slovenian: Terenska študija je pokazala, da je bilo zdravilo Cardalis prostovoljno in v celoti zaužito v 92 % primerov, ko je bilo ponujeno s hrano ali brez nje, 86 % psov pa je dobro sodelovalo pri zdravljenju.
English: The safety study showed Cardalis to have a good safety profile.
Slovenian: Študija varnosti je pokazala, da ima zdravilo Cardalis dober varnostni profil.
English: Spironolactone also works on the heart and blood vessels in other ways, although these mechanisms have not yet been fully demonstrated in dogs.
Slovenian: Spironolakton na srce in krvne žile deluje tudi na druge načine, čeprav teh mehanizmov delovanja pri psih še niso popolnoma dokazali.
English: What benefit has Cardalis shown during the studies?
Slovenian: Kakšne koristi je zdravilo Cardalis izkazalo med študijami?
English: A field study was conducted in dogs to demonstrate how well Cardalis tablets were taken and how easy they were to give.
Slovenian: Terenska študija pri psih je bila izvedena, da bi prikazali, kako dobro so bile tablete zdravila Cardalis zaužite in kako enostavno je bilo njihovo dajanje.
English: The tablets are given to the dog once a day with food at a dose of 0.25 mg benazepril hydrochloride and 2 mg spironolactone per kilogram bodyweight.
Slovenian: Tablete se dajejo psu enkrat na dan skupaj s hrano v odmerku 0,25 mg benazeprilhidroklorida in 2 mg spironolaktona na kilogram telesne mase.
English: Benazepril hydrochloride / spironolactone
Slovenian: Cardalis benazeprilhidroklorid/spironolakton
English: The company also presented the results of field studies with the individual active substances given as separate tablets, where the main measure of effectiveness was the number of dogs that died due to heart disease.
Slovenian: Družba je predstavila tudi rezultate terenskih študij s posamičnima zdravilnima učinkovinama, danima v ločenih tabletah, pri čemer je bilo glavno merilo učinkovitosti število psov, ki so zaradi obolenja srca poginili.
English: What is the risk associated with Cardalis?
Slovenian: Kakšna tveganja so povezana z zdravilom Cardalis?
English: Pregnant women should take special care to avoid accidental oral exposure because ACE inhibitors have been found to affect the unborn child.
Slovenian: Nosečnice morajo biti posebno previdne in preprečiti nenamerno peroralno izpostavljenost, saj je bilo ugotovljeno, da zaviralci ACE vplivajo na nerojenega otroka.
English: Information on the prescription status of this product can be found on the label/outer package.
Slovenian: Podatki o predpisovanju zdravila so navedeni na nalepki/zunanji ovojnini.
English: This allows the blood pressure to drop, reducing the load on the heart.
Slovenian: S tem se krvni tlak zniža in obremenitev srca zmanjša.
English: This decreases the overall blood volume, reducing the effort needed for the heart to pump blood and thereby improving its function.
Slovenian: S tem se zmanjša splošni krvni volumen, zaradi česar srce potrebuje manj moči za črpanje krvi, kar izboljša njegovo delovanje.
English: Benazepril is a prodrug, a substance that is converted to benazeprilat in the body.
Slovenian: Benazepril je predzdravilo, snov, ki se v telesu pretvori v benazeprilat.
English: Cardalis should not be given to growing dogs due to its effect on male sex hormones.
Slovenian: Odraščajoči psi zdravila Cardalis ne smejo prejemati zaradi vpliva na moške spolne hormone.
English: In the laboratory study, Cardalis was shown to be bioequivalent to combined treatment with products containing the single active substances (medicines are bioequivalent when they produce the same levels of active substance in the body).
Slovenian: V laboratorijski študiji se je pokazalo, da je zdravilo Cardalis biološko enakovredno kombiniranemu zdravljenju z zdravili, ki vsebujejo samo eno zdravilno učinkovino (zdravila so biološko enakovredna, kadar v telesu dosegajo enake ravni zdravilne učinkovine).
English: People with known hypersensitivity (allergy) to spironolactone or benazepril should avoid contact with Cardalis.
Slovenian: Osebe z znano preobčutljivostjo za (alergijo na) spironolakton ali benazepril naj se stiku z zdravilom Cardalis izogibajo.
English: Cardalis is a veterinary medicine that contains two active substances, benazepril hydrochloride and spironolactone.
Slovenian: Cardalis je zdravilo za uporabo v veterinarski medicini, ki vsebuje dve zdravilni učinkovini, benazeprilhidroklorid in spironolakton.
English: Why has Cardalis been approved?
Slovenian: Zakaj je bilo zdravilo Cardalis odobreno?
English: This allowed the existing field data on the single active substances to be applied to Cardalis.
Slovenian: Zato je bilo mogoče obstoječe podatke s terena o posamezni zdravilni učinkovini uporabiti za zdravilo Cardalis.
English: A six month safety study was also conducted in Beagle dogs at up to five times the recommended dose.
Slovenian: Pri psih pasme beagle so izvedli tudi šestmesečno študijo o varnosti s petkratnikom priporočenega odmerka.
English: ACE inhibitors lower the production of angiotensin II, a powerful vasoconstrictor (a substance that narrows blood vessels).
Slovenian: Zaviralci ACE zmanjšujejo nastajanje angiotenzina II, ki je močan vazokonstriktor (snov, ki oži krvne žile).
English: It must not be used in dogs which are hypersensitive (allergic) to ACE inhibitors or to any of the ingredients.
Slovenian: Ne sme se uporabljati pri psih, ki so preobčutljivi za (alergični na) zaviralce ACE ali katero koli drugo sestavino zdravila.
English: Spironolactone blocks the actions of aldosterone, a hormone that causes the kidneys to retain salt and water within the body with harmful effects on the cardiovascular system.
Slovenian: Spironolakton zavira delovanje aldosterona, hormona, zaradi katerega ledvice zadržujejo sol in vodo v telesu, kar škodljivo vpliva tudi na srčno-žilni sistem.
English: By blocking aldosterone, spironolactone increases the elimination of salt and water in the urine.
Slovenian: Spironolakton blokira aldosteron in s tem poveča izločanje soli in vode v seču.
English: Benazeprilat is an ‘angiotensin converting enzyme (ACE) inhibitor'.
Slovenian: Benazeprilat je „zaviralec encima angiotenzinske konvertaze (ACE)“.
English: The company presented a laboratory study in Beagle dogs comparing treatment with spironolactone and benazepril as single active substances (in the products Prilactone and Fortekor which are already authorised in the EU) to treatment with Cardalis.
Slovenian: Družba je predložila laboratorijsko študijo pri psih pasme beagle, v kateri so primerjali zdravljenje s spironolaktonom in benazeprilom kot edinima zdravilnima učinkovinama (v zdravilih Prilactone oziroma Fortekor, ki že imata dovoljenje za promet z zdravilom v EU) z zdravljenjem z zdravilom Cardalis.
English: Cardalis is used to treat dogs with congestive heart failure.
Slovenian: Zdravilo Cardalis se uporablja za zdravljenje psov s kongestivnim srčnim popuščanjem.
English: Cardalis is used for congestive heart failure caused by long-term damage to the heart valves.
Slovenian: Zdravilo Cardalis se uporablja za kongestivno popuščanje srca, ki ga povzroči dolgotrajna poškodba srčnih zaklopk.
English: Cardalis must not be used in cases of aortic or pulmonary stenosis (narrowing of the aorta or pulmonary blood vessels) affecting the heart's blood output.
Slovenian: Zdravilo Cardalis se ne sme uporabiti v primerih aortne ali pljučne stenoze (zoženja aorte ali pljučnih krvnih žil), ki vpliva na iztis krvi iz srca.
English: Regular monitoring should continue in dogs with reduced kidney function as they may have an increased risk of hyperkalaemia (raised potassium levels in the blood) during treatment.
Slovenian: Redno nadziranje je treba nadaljevati pri psih z zmanjšanim delovanjem ledvic, saj je pri njih morda tveganje za hiperkaliemijo (zvišano raven kalija v krvi) med zdravljenjem večje.
English: Cardalis must not be used in dogs with Addison's disease or hypoadrenocorticism (a condition where the adrenal gland does not produce sufficient amounts of hormones), hyperkalaemia (increased blood potassium levels) or hyponatraemia (reduced blood sodium levels).
Slovenian: Zdravilo Cardalis se ne sme uporabljati pri psih z Addisonovo boleznijo ali hipoadrenokorticizmom (stanjem, pri katerem v nadledvični žlezi ne nastaja dovolj hormonov), hiperkaliemijo (zvišano ravnjo kalija v krvi) ali hiponatriemijo (znižano ravnjo natrija v krvi).
English: These studies demonstrated an increased survival in dogs treated concurrently with spironolactone and benazepril compared to benazepril alone.
Slovenian: Študije so pokazale, da je bilo preživetje psov, ki so bili sočasno zdravljeni s spironolaktonom in benazeprilom, večje v primerjavi s psi, ki so bili zdravljeni samo s benazeprilom.
English: In case of accidental ingestion, medical advice should be sought immediately and the package leaflet or the label shown to the doctor.
Slovenian: V primeru nenamernega zaužitja takoj poiščite zdravniško pomoč in zdravniku pokažite navodilo za uporabo ali ovojnino.
English: Cardalis must not be used in pregnant or lactating (milk producing) bitches as toxic effects for the foetus were seen in studies of benazepril in rats.
Slovenian: Zdravilo Cardalis se ne sme uporabiti pri psicah, ki so breje ali v laktaciji (doječe), saj so v študijah benazeprila pri podganah opazili toksične učinke na zarodke.
English: Cardalis should be used with caution in dogs with liver damage as this may alter the way spironolactone is metabolised (processed) in the liver.
Slovenian: Zdravilo Cardalis je treba pri psih s poškodovanimi jetri uporabljati previdno, saj lahko spremeni način presnavljanja (obdelave) spironolaktona v jetrih.
English: Non-castrated male dogs treated with spironolactone may show atrophy (wasting) of the prostrate (a gland of the male reproductive system) that is reversible.
Slovenian: Pri nekastriranih psih, zdravljenih s spironolaktonom, lahko pride do reverzibilne atrofije (izginjanja) prostate (žleze moškega reprodukcijskega sistema).
English: What is Cardalis used for?
Slovenian: Za kaj se zdravilo Cardalis uporablja?
English: How has Cardalis been studied?
Slovenian: Kako je bilo zdravilo Cardalis raziskano?