FrancophonIA/ELRC3.0 huggingface dataset:
English: 1 ml of reconstituted suspension contains 10 mg fluconazole.
Maltese: U KWANTITATTIVA 1 ml tas-sospensjoni rikostitwita fih 10 mg ta' fluconazole.
English: Quinidine: Although not studied in vitro or in vivo, concomitant administration of fluconazole with quinidine may result in inhibition of quinidine metabolism.
Maltese: Għalkemm ma ġiex studjat in vitro jew in vivo, l-għoti konkomittanti ta' fluconazole ma' quinidine jista' jirriżulta fl-inibizzjoni tal-metaboliżmu ta' quinidine.
English: Although not specifically studied, fluconazole has the potential to increase the systemic exposure of other NSAIDs that are metabolized by CYP2C9 (e.g. naproxen, lornoxicam, meloxicam, diclofenac).
Maltese: Għalkemm ma ġiex studjat b'mod speċifiku, fluconazole għandu l-potenzjal li jżid l-espożizzjoni sistemika ta' NSAIDs oħrajn li huma metabolizzati permezz ta' CYP2C9 (eż. naproxen, lornoxicam, meloxicam, diclofenac).
English: Pimozide: Although not studied in vitro or in vivo, concomitant administration of fluconazole with pimozide may result in inhibition of pimozide metabolism.
Maltese: Għalkemm ma ġiex studjat in vitro jew in vivo, l-għoti konkomittanti ta' fluconazole ma' pimozide jista' jirriżulta fl-inibizzjoni tal-metaboliżmu ta' pimozide.
English: Fluconazole is also an inhibitor of CYP2C19.
Maltese: Fluconazole huwa wkoll inibitur ta' CYP2C19.
English: Tacrolimus: Fluconazole may increase the serum concentrations of orally administered tacrolimus up to 5 times due to inhibition of tacrolimus metabolism through CYP3A4 in the intestines.
Maltese: Fluconazole jista' jżid il-konċentrazzjonijiet fis-serum ta' tacrolimus mogħti mill-ħalq sa 5 darbiet minħabba l-inibizzjoni tal-metaboliżmu ta' tacrolimus permezz ta' CYP3A4 fl-intestini.
English: Elderly The usual adult dose should be given unless you have kidney problems.
Maltese: Anzjani Għandha tingħata d-doża normali tal-adulti sakemm m'għandekx problemi fil-kliewi.
English: A 5 ml measuring spoon and/or a 5 ml graduated syringe with a press-in bottle adaptor might also be provided with the 60 ml bottle.
Maltese: Mgħarfa tal-kejl ta' 5 ml u/jew siringa mmarkata ta' 5 ml b'adapter tal-flixkun li jintgħafas 'il ġewwa jistgħu jiġu pprovduti wkoll mal-flixkun ta' 60 ml.
English: Diflucan is used for the treatment of mucosal candidiasis (oropharyngeal, oesophageal), invasive candidiasis, cryptococcal meningitis and the prophylaxis of candidal infections in immunocompromised patients.
Maltese: Diflucan jintuża għall-kura ta' kandidjażi mukożali (orofarinġeali, esofaġeali), kandidjażi invażiva, meninġite kriptokokkali u l-profilassi ta' infezzjonijiet kandidali f'pazjenti immunokompromessi.
English: Male rats treated with 5 and 10 mg/kg/day had an increased incidence of hepatocellular adenomas.
Maltese: Il-firien irġiel ikkurati b'5 u 10 mg/kg/jum kellhom aktar inċidenza ta' adenomi epatoċellulari.
English: Diflucan is used for the treatment of mucosal candidiasis (oropharyngeal, oesophageal), invasive candidiasis and cryptococcal meningitis and the prophylaxis of candidal infections in immunocompromised patients.
Maltese: Diflucan jintuża għall-kura ta' kandidjażi mukożali (orofarinġeali, esofaġeali), kandidjażi invażiva u meninġite kriptokokkali u l-profilassi ta' infezzjonijiet kandidali f'pazjenti immunokompromessi.
English: • Prophylaxis of candidal infections in patients with prolonged neutropenia (such as patients with haematological malignancies receiving chemotherapy or patients receiving Hematopoietic Stem Cell Transplantation (see section 5.1)).
Maltese: • Profilassi ta' infezzjonijiet kandidali f'pazjenti b'newtropenja fit-tul (bħal pazjenti b'kundizzjonijiet ematoloġiċi malinni li qed jirċievu l-kimoterapija jew pazjenti li qed jirċievu Trapjant taċ-Ċelluli Staminali Ematopojetiċi (ara sezzjoni 5.1)
English: Half of the celecoxib dose may be necessary when combined with fluconazole.
Maltese: Tista' tkun meħtieġa nofs id-doża ta' celecoxib meta kkombinat ma' fluconazole.
English: - Maintenance therapy to prevent relapse of cryptococcal meningitis in patients with high risk of recurrence.
Maltese: - Terapija ta' manteniment sabiex jiġi evitat li jkun hemm rikadenza ta' meninġite kriptokokkali fit-tfal b'riskju għoli ta' rikorrenza.
English: Fluconazole 50 mg daily given up to 28 days has been shown not to effect testosterone plasma concentrations in males or steroid concentration in females of child-bearing age.
Maltese: Fluconazole 50 mg kuljum mogħti għal 28 jum intwera li ma jaffettwax il-konċentrazzjonijiet filplażma tat-testosterone fl-irġiel jew il-konċentrazzjoni ta' sterojdi fin-nisa ta' età li jkollhom it-tfal.
English: - prednisone (steroid) - zidovudine, also known as AZT; saquinavir (used in HIV-infected patients) - medicines for diabetes such as chlorpropamide, glibenclamide, glipizide or tolbutamide - theophylline (used to control asthma) - vitamin A (nutritional supplement)
Maltese: - zidovudine, magħruf ukoll bħala AZT; saquinavir (użat f'pazjenti infettati bl-HIV) - mediċini għad-dijabete bħal chlorpropamide, glibenclamide, glipizide jew tolbutamide - theophylline (użat fil-kontroll tal-ażżma) - vitamina A (suppliment nutrittiv)
English: Gastrointestinal
Maltese: Disturbi gastro
English: Each 50 ml solution for infusion contains 100 mg fluconazole.
Maltese: Kull soluzzjoni ta' 50 ml għal infużjoni fiha 100 mg fluconazole.
English: Coadministration of other medicinal products known to prolong the QT interval and which are metabolised via the cytochrome P450 (CYP) 3A4 are contraindicated (see sections 4.3 and 4.5).
Maltese: L-amministrazzjoni flimkien ma' prodotti mediċinali oħra li huma magħrufin li jtawwlu l-intervall talQT u li huma metabolizzati permezz ta' ċitokromu P450 (CYP) 3A4 hija kontraindikata (ara sezzjonijiet 4.3 u 4.5).
English: Loading dose: 400 mg on Day 1 Subsequent dose: 200 mg to 400 mg daily
Maltese: Doża inizjali għolja: 400 mg flewwel Ġurnata Doża sussegwenti: 200 mg sa 400 mg kuljum
English: In patients with fungal meningitis, fluconazole levels in the CSF are approximately 80% the corresponding plasma levels.
Maltese: F'pazjenti b'meninġite fungali, il-livelli ta' fluconazole fis-CSF huma madwar 80% tal-livelli fil-plażma korrispondenti.
English: The shelf life of the reconstituted suspension is 28 days.
Maltese: Is-sospensjoni rikostitwita ddum tajba 28 ġurnata.
English: The levels of fluconazole in saliva and sputum are similar to plasma levels.
Maltese: Il-livelli ta' fluconazole filbżieq u l-isputum huma simili għal-livelli fil-plażma.
English: Hypersensitivity to the active substance, to related azole substances, or to any of excipients (see section 6.1).
Maltese: Sensittività eċċessiva għas-sustanza attiva, għal sustanzi azole relatati, jew għal xi sustanzi mhux attivi (ara sezzjoni 6.1).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION 1 ml of oral solution contains 5 mg of fluconazole.
Maltese: U KWANTITATTIVA 1 ml ta' soluzzjoni orali fih 5 mg ta' fluconazole.
English: The 150 mg hard gelatin capsule has a turquoise blue body and turquoise blue cap overprinted with “Pfizer” and the code “FLU-150” with black ink.
Maltese: Il-kapsula iebsa tal-ġelatina ta' 150 mg għandha kulur blu turkważ u l-parti ta' fuq blu turkważ bi “Pfizer” u l-kodiċi “FLU-150” stampati fuqha b'linka sewda.
English: Intravenous infusion should be administrated at a rate not exceeding 10 ml/minute.
Maltese: Infużjoni ġol-vini għandha tingħata b'rata li ma taqbiżx 10 ml/minuta.
English: • Tinea unguinium (onychomycosis) when other agents are not considered appropriate.
Maltese: • Tinea unguinium (onychomycosis) meta sustanzi oħra ma jistawx jiġu wżati.
English: What Diflucan 50 mg, 100 mg, 150 mg and 200 mg hard capsules look like and contents of the pack
Maltese: Id-dehra ta' Diflucan kapsuli iebsin ta' 50 mg, 100 mg, 150 mg u 200 mg u l-kontenuti talpakkett
English: STATEMENT OF ACTIVE SUBSTANCE(S) 1 ml of reconstituted suspension contains 10 mg fluconazole.
Maltese: ATTIVA(I) 1 ml tas-sospensjoni rikostitwita fih 10 mg ta' fluconazole.
English: Based on analyses of pharmacokinetic/pharmacodynamic (PK/PD) data, susceptibility in vitro and clinical response EUCAST-AFST (European Committee on Antimicrobial susceptibility Testing-subcommittee on Antifungal Susceptibility Testing) has determined breakpoints for fluconazole for Candida species (EUCAST Fluconazole rational document (2007)-version 2).
Maltese: Skont l-analiżi ta' informazzjoni farmakokinetika/farmakodinamika (FK/FD), is-suxxettibbiltà in vitro u r-reazzjoni klinika EUCAST-AFST (European Committee on Antimicrobial susceptibility Testing-subcommittee on Antifungal Susceptibility Testing) - Il-Kumitat Ewropew għall-Ittestjar tas-Suxxettibbiltà Antimikrobjali-Sottokumitat dwar l-Ittestjar tasSuxxettibbiltà Antifungali) stabbilixxa breakpoints għal fluconazole għall-ispeċijiet Candida (EUCAST Dokument razzjonali għal Fluconazole (2007)-verżjoni 2).
English: Frequent monitoring for adverse events and toxicity related to NSAIDs is recommended.
Maltese: Hija rrakkomandata sorveljanza regolari għal avvenimenti avversi u tossiċità relatati mal-NSAIDs.
English: Concomitant treatment with fluconazole and cisapride is contraindicated (see section 4.3).
Maltese: It-trattament konkomittanti bi fluconazole u cisapride huwa kontra-indikat (ara sezzjoni 4.3).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each 25 ml solution for infusion contains 50 mg fluconazole.
Maltese: Kull soluzzjoni ta' 25 ml għal infużjoni fiha 50 mg fluconazole.
English: Important information about some of the ingredients of Diflucan Diflucan contains 0.154 mmol sodium per ml.
Maltese: Tagħrif importanti dwar xi wħud mis-sustanzi ta' Diflucan Diflucan fih 0.154 mmol sodium għal kull ml.
English: Vaginal thrush
Maltese: AKTAR TAGĦRIF
English: Each 50 ml solution for infusion contains 100 mg fluconazole Each 100 ml solution for infusion contains 200 mg fluconazole Each 200 ml solution for infusion contains 400 mg fluconazole
Maltese: Kull soluzzjoni ta' 50 ml għal infużjoni fiha 100 mg fluconazole Kull soluzzjoni ta' 100 ml għal infużjoni fiha 200 mg fluconazole Kull soluzzjoni ta' 200 ml għal infużjoni fiha 400 mg fluconazole
English: gattii as well as the endemic moulds Blastomyces dermatiditis, Coccidioides immitis, Histoplasma capsulatum and Paracoccidioides brasiliensis.
Maltese: Fluconazole juri wkoll attività in vitro kontra Cryptococcus neoformans u Cryptococcus. gattii kif ukoll il-fungi endemiċi Blastomyces dermatiditis, Coccidioides immitis, Histoplasma capsulatum u Paracoccidioides brasiliensis.
English: STATEMENT OF ACTIVE SUBSTANCE(S) 1 ml of reconstituted suspension contains 40 mg fluconazole.
Maltese: ATTIVA(I) 1 ml tas-sospensjoni rikostitwita fih 40 mg ta' fluconazole.
English: Hypersensitivity In rare cases anaphylaxis has been reported (see section 4.3).
Maltese: F'każijiet rari, ġiet irrapportata anafilassi (ara sezzjoni 4.3).
English: 200 mg to 400 mg once daily while you are at risk of getting an infection
Maltese: 200 sa 400 mg darba kuljum filwaqt li tkun f'riskju li tieħu infezzjoni
English: Capsule shell composition:
Maltese: Kompożizzjoni tal-qoxra tal-kapsula:
English: LIST OF EXCIPIENTS Contains sucrose.
Maltese: LISTA TA' SUSTANZI MHUX ATTIVI Fih sucrose.
English: Single dose 150 mg.
Maltese: Doża waħda ta' 150mg.
English: PHARMACEUTICAL FORM AND CONTENTS Oral solution.
Maltese: U KONTENUT Soluzzjoni orali.
English: What Diflucan solution for infusion contains - The active substance is fluconazole.
Maltese: X'fih Diflucan soluzzjoni għal infużjoni - Is-sustanza attiva hija fluconazole.
English: After reconstitution, the volume of the suspension is 110 ml, providing a usable volume of 100 ml.
Maltese: Wara rikostituzzjoni, il-volum tassospensjoni huwa 110 ml, li jipprovdi volum użabbli ta' 100 ml.
English: Glycerol may cause headache, stomach upset, and diarrhoea (see section 4.8).
Maltese: Glycerol jista' jikkawża uġigħ ta' ras, tqallib ta' stonku u dijarrea (ara sezzjoni 4.8).
English: For storage conditions of the reconstituted medicinal product, see section 6.3.
Maltese: Għall-kundizzjonijiet ta' ħżin tal-prodott mediċinali rikostitwit, ara sezzjoni 6.3.
English: Other side effects:
Maltese: Doża sussegwenti:
English: (Non-Steroidal Anti-Inflammatory Drugs (NSAID)) - oral contraceptives - prednisone (steroid) - zidovudine, also known as AZT; saquinavir (used in HIV-infected patients) - medicines for diabetes such as chlorpropamide, glibenclamide, glipizide or tolbutamide - theophylline (used to control asthma) - vitamin A (nutritional supplement)
Maltese: Sterojdi ta' Kontra l-Infjammazzjoni - Non-Steroidal Anti-Inflammatory Drugs (NSAID)) - kontraċettivi orali - prednisone (sterojde) - zidovudine, magħruf ukoll bħala AZT; saquinavir (użat f'pazjenti infettati bl-HIV) - mediċini għad-dijabete bħal chlorpropamide, glibenclamide, glipizide jew tolbutamide - theophylline (użat fil-kontroll tal-ażżma) - vitamina A (suppliment nutrittiv)
English: Hepatic failure (see section 4.4), hepatocellular necrosis (see section 4.4), hepatitis (see section 4.4), hepatocellular damage (see section phosphatase increased (see section 4.4)
Maltese: Insuffiċjenza epatika (ara sezzjoni 4.4), nekrożi epatoċellulari (ara sezzjoni 4.4), epatite (ara sezzjoni 4.4), ħsara epatoċellulari (ara sezzjoni 4.4)
English: Cherry liquid flavor
Maltese: KIF TAĦŻEN DIFLUCAN
English: - Diflucan 200 mg hard capsules have a white body and a purple cap.
Maltese: - Diflucan 200 mg kapsuli iebsin għandhom il-parti ewlenija bajda u l-parti ta' fuq vjola.
English: Fluconazole 200 mg to 400 mg daily has no clinically significant effect on endogenous steroid levels or on ACTH stimulated response in healthy male volunteers.
Maltese: Fluconazole 200 mg sa 400 mg kuljum m'għandu l-ebda effett klinikament sinifikanti fuq livelli ta' sterojdi endoġeni jew fuq ir-reazzjoni stimulata mill-ACTH f'voluntiera rġiel b'saħħithom.
English: 1, 5, 10 or 20 plasticised PVC bags (100 or 200 ml).
Maltese: kunjetti tal-ħġieġ ta' 30, 50, 100 jew 250 ml. 1, 5, 10, 20 boroż tal-PVC bil-plastik (100 jew 200 ml).
English: A = Non-species related breakpoints have been determined mainly on the basis of PK/PD data and are independent of MIC distributions of specific species.
Maltese: A = Breakpoints mhux relatati mal-ispeċijiet ġew stabbiliti primarjament fuq il-bażi ta' informazzjoni FK/FD u huma indipendenti mid-distribuzzjonijiet tal-MIC ta' speċijiet speċifiċi.
English: Concomitant use of the following other medicinal products is contraindicated:
Maltese: Mediċini mhux sterojdi kontra l-infjammazzjoni:
English: The 100 mg hard gelatin capsule has a white body and blue cap overprinted with “Pfizer” and the code “FLU-100” with black ink.
Maltese: Il-kapsula iebsa tal-ġelatina ta' 100 mg għandha kulur abjad u l-parti ta' fuq blu bi “Pfizer” u l-kodiċi “FLU-100” stampati fuqha b'linka sewda.
English: The evidence for efficacy of fluconazole in the treatment of other forms of endemic mycoses such as paracoccidioidomycosis, lymphocutaneous sporotrichosis and histoplasmosis is limited, which prevents specific dosing recommendations.
Maltese: L-evidenza tal-effikaċja ta' fluconazole għal kura ta' forom oħra ta' mikożi endemika bħal paracoccidioidomycosis, lymphocutaneous sporotrichosis u histoplasmosis hija limitata, li tevita rakkomandazzjonijiet speċifiċi dwar id-doża.
English: The combined use of fluconazole at doses of 400 mg or greater with terfenadine is contraindicated (see section 4.3).
Maltese: L-użu kkombinat ta' fluconazole f'dożi ta' 400 mg jew aktar ma' terfenadine huwa kontra-indikat (ara sezzjoni 4.3).
English: Patients with rare hereditary problems of fructose intolerance, glucose/galactose malabsorption and sucrase-isomaltase insufficiency should not take this medicine.
Maltese: Pazjenti bi problemi ereditarji rari ta' nuqqas ta' tolleranza għal fructose, nuqqas ta' assorbiment ta' glucose/galactose u insuffiċjenza ta' sucraseisomaltase m'għandhomx jieħdu din il-mediċina.
English: Adolescents from 12 to 17 years old Follow the dose prescribed by your doctor (either adults or children posology).
Maltese: Adoloxxenti minn 12 sa 17-il sena Segwi d-doża li tak it-tabib tiegħek (jew id-doża tal-adulti jew id-doża tat-tfal).
English: Coadministration of fluconazole and pimozide is contraindicated (see section 4.3).
Maltese: L-għoti flistess waqt ta' fluconazole u pimozide huwa kontra-indikat (ara sezzjoni 4.3).
English: Azithromycin: An open-label, randomized, three-way crossover study in 18 healthy subjects assessed the effect of a single 1200 mg oral dose of azithromycin on the pharmacokinetics of a single 800 mg oral dose of fluconazole as well as the effects of fluconazole on the pharmacokinetics of azithromycin.
Maltese: Studju open-label, b'mod fortuwitu, crossover fi tliet modi f'18-il suġġett b'saħħtu evalwa l-effett ta' doża orali waħda ta' 1200 mg ta' azithromycin fuq il-farmakokinetika ta' doża orali waħda ta' 800 mg ta' fluconazole kif ukoll l-effetti ta' fluconazole fuq il-farmakokinetika ta' azithromycin.
English: At doses ranging from 80 mg/kg to 320 mg/kg embryolethality in rats was increased and foetal abnormalities included wavy ribs, cleft palate, and abnormal cranio-facial ossification.
Maltese: F'dożi li jvarjaw minn 80 mg/kg sa 320 mg/kg żdiedet il-mewt tal-embriju fil-firien u l-anormalitajiet filfetu kienu jinkludu kustilji mmewġa, palat mixquq, u ossifikazzjoni anormali tal-kranju u tal-wiċċ.
English: Fluconazole 200 mg daily given concurrently with triazolam 0.25 mg orally increased the triazolam AUC and half-life 4.4-fold and 2.3-fold, respectively.
Maltese: Meta fluconazole 200 mg kuljum ingħata fl-istess waqt ma' triazolam 0.25 mg b'mod orali, kien hemm żieda ta' 4.4 u 2.3 aktar fl-AUC u l-half-life ta' triazolam rispettivament.
English: Dermatological reactions
Maltese: Reazzjonijiet dermatoloġiċi
English: For instructions on reconstitution of the powder for oral suspension, (see section 6.6).
Maltese: Għal struzzjoni dwar ir-rikostituzzjoni tat-trab għal sospensjoni orali, (ara sezzjoni 6.6).
English: There have been reports of superinfection with Candida species other than C. albicans, which are often inherently not susceptible to fluconazole (e.g. Candida krusei).
Maltese: Kien hemm rapporti ta' superinfezzjoni bi speċijiet ta' Candida minbarra C. albicans, li naturalment spiss ma jkunux suxxettibbli għal fluconazole (eż. Candida krusei).
English: • To reduce the incidence of recurrent vaginal candidiasis (4 or more episodes a year).
Maltese: • Tnaqqis fl-inċidenza ta' kandidjażi vaġinali rikorrenti (4 episodji jew aktar f'sena).
English: [See Annex I - To be completed nationally] fluconazole
Maltese: [Ara Anness I - Sabiex timtela mill-pajjiż] fluconazole
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each hard capsule contains fluconazole 150 mg.
Maltese: Kull kapsula iebsa fiha fluconazole 150 mg.
English: Everolimus: Although not studied in vivo or in vitro, fluconazole may increase serum concentrations of everolimus through inhibition of CYP3A4.
Maltese: Għalkemm ma ġiex studjat in vivo jew in vitro, fluconazole jista' jżid il-konċentrazzjonijiet ta' everolimus fis-serum permezz ta' inibizzjoni ta' CYP3A4.
English: Fluconazole is a selective inhibitor of the isozymes CYP2C9 and CYP3A4 (see section 4.5).
Maltese: medda terapewtika żgħira metabolizzati permezz ta' CYP2C9, CYP2C19 u CYP3A4, għandhom jiġu ssorveljati (ara sezzjoni 4.5).
English: - Chronic mucocutaneous candidiasis
Maltese: - Kandidjażi mukokutanja kronika
English: • Chronic oral atrophic candidiasis (denture sore mouth) if dental hygiene topical treatment are insufficient.
Maltese: • Kandidjażi atrofika orali kronika (ħalq misluħ fid-dentatura) jekk l-iġjene tas-snien jew kura topika ma jkunux biżżejjed.
English: 3 mg to 12 mg per kg of body weight
Maltese: 3 mg sa 12 mg għal kull kg tal-piż talġisem
English: BATCH NUMBERS
Maltese: NUMRU TAL-LOTT
English: PHARMACEUTICAL FORM AND CONTENTS Powder for oral suspension.
Maltese: U KONTENUT Trab għal sospensjoni orali.
English: Diflucan and associated names (see Annex 1) 50 mg hard capsules Diflucan and associated names (see Annex 1) 100 mg hard capsules Diflucan and associated names (see Annex 1) 150 mg hard capsules Diflucan and associated names (see Annex 1) 200 mg hard capsules [See Annex I - To be completed nationally]
Maltese: Diflucan u l-ismijiet assoċjati (ara Anness 1) 50 mg kapsuli iebsin Diflucan u l-ismijiet assoċjati (ara Anness 1) 100 mg kapsuli iebsin Diflucan u l-ismijiet assoċjati (ara Anness 1) 150 mg kapsuli iebsin Diflucan u l-ismijiet assoċjati (ara Anness 1) 200 mg kapsuli iebsin [Ara Anness I - Sabiex timtela mill-pajjiż]
English: - Diflucan 50 mg hard capsules have a white body and a turquoise blue cap.
Maltese: - Diflucan 50 mg kapsuli iebsin għandhom il-parti ewlenija bajda u l-parti ta' fuq blu turkważ.
English: Carcinogenesis
Maltese: Karċinoġenesi
English: Saquinavir: Fluconazole increases the AUC and Cmax of saquinavir with approximately 50% and 55% respectively, due to inhibition of saquinavir's hepatic metabolism by CYP3A4 and inhibition of P-glycoprotein.
Maltese: Fluconazole iżid l-AUC u is-Cmax ta' saquinavir b'madwar 50% u 55%, rispettivament minħabba l-inibizzjoni tal-metaboliżmu epatiku ta' saquinavir permezz ta' CYP3A4 u l-inibizzjoni ta' P-glycoprotein.
English: Seven patients completed the protocol; a maximum of five 6 mg/kg intravenous infusions of fluconazole were administered every 72 hours.
Maltese: Seba' pazjenti lestew il-protokoll; ingħataw massimu ta' ħames infużjonijiet minn ġol-vini ta' 6 mg/kg ta' fluconazole kull 72 siegħa.
English: - Diflucan 100 mg hard capsules have a white body and a blue cap.
Maltese: - Diflucan 100 mg kapsuli iebsin għandhom il-parti ewlenija bajda u l-parti ta' fuq blu.
English: A 60 ml or a 175 ml high density polyethylene (HDPE) bottle with either a plastic child-resistant closure or continuous thread aluminum closure containing a white to off-white powder for oral suspension providing a white to off-white orange-flavoured suspension after reconstitution.
Maltese: Flixkun tal-politilene ta' densità għolja (HDPE) ta' 60 ml jew ta' 175 ml b'tapp tal-plastik reżistenti għat-tfal jew b'għeluq tal-aluminju b'kamin kontinwu li fih trab abjad jew ofwajt għal sospensjoni orali li jipprovdi sospensjoni togħma tal-larinġ bajda għal ofwajt wara rikostituzzjoni.
English: 50 mg once daily 2 to 4 weeks
Maltese: 50 mg darba kuljum2 sa 4 ġimgħat
English: Excipients
Maltese: Ġelatina
English: The 200 mg hard gelatin capsule has a white body and a purple cap overprinted with “Pfizer” and the code “FLU-200” with black ink.
Maltese: Il-kapsula iebsa tal-ġelatina ta' 200 mg għandha kulur abjad u l-parti ta' fuq vjola bi “Pfizer” u lkodiċi “FLU-200” stampati fuqha b'linka sewda.
English: Dose: 6 to 12 mg/kg daily
Maltese: Doża massima ta' 12 mg/kg kull 72
English: These pharmacokinetic parameter values are higher than analogous values reported for normal young male volunteers.
Maltese: Dawn il-valuri ta' parametri farmakokinetiċi huma ogħla mill-valuri analogi rrapportati għal voluntiera rġiel żgħażagħ normali.
English: The combination may be used while taking increased consideration to the risk of increased serum bilirubin and serum creatinine.
Maltese: Il-kombinazzjoni tista' tintuża filwaqt li jiġi kkunsidrat aktar irriskju ta' żieda tal-bilirubin fis-serum u tal-kreatinina fis-serum.