FrancophonIA/ELRC3.0 huggingface dataset:
English: Alfacalcidol improves muscle power, muscle function and balance in elderly patients with reduced bone mass. Rheumatol Int 2012;32(1):207-15.
Croatian: Alfacalcidol improves muscle power, muscle function and balance in elderly patients with reduced bone mass.
English: The applicant claimed that since no significant difference in numbers of falls was found between the groups treated with the combination of ‘alendronate + alfacalcidol' and ‘alfacalcidol alone', this underlines the efficacy of alfacalcidol as monotherapy as well as in combination with alendronate for the reduction of falls.
Croatian: tvrdio je da nema značajnih razlika u količini padova utvrđenoj za svaku grupu liječenu kombinacijom „alendronata + alfakalcidola” i „monoterapijom alfakalcidola”.
English: Meta-analysis of trials on alfacalcidol and calcitriol investigating fallers
Croatian: Meta analiza ispitivanja u osoba koje padaju, a uzimaju alfakalcidolon i kalcitriolon
English: Dukas L, Bischoff HA, Lindpainter LS, Schacht E, Birkner-Binder D, Damm TN, Thalman B, Stähelin HB. Alfacalcidol reduces the number of fallers in a community-dwelling elderly population with a minimum calcium intake of more than 500 mg daily.
Croatian: Dukas L, Bischoff HA, Lindpainter LS, Schacht E, Birkner-Binder D, Damm TN, Thalman B, Stähelin HB.
English: Date of first authorisation: 06/11/2015.
Croatian: Datum prvog odobrenja: 06/11/2015
English: One carton contains one blister of 1, 3 or 6 tablets.
Croatian: Jedna kartonska kutija sadrži jedan blister s 1, 3 ili 6 tableta.
English: Aluminium foil/foil blister package.
Croatian: Aluminijska folija/folija blister pakovanje.
English: The bioavailability of sarolaner following oral dosing was high at >85%.
Croatian: Biološka raspoloživost sarolanera nakon peroralne primjene visoka je >85%.
English: The depletion from tissues was consistent with the plasma half-life.
Croatian: Deplecija iz tkiva je u skladu s polu-životom u plazmi.
English: Half-life was comparable for the intravenous and oral routes at 12 and 11 days, respectively.
Croatian: Poluživot je usporediv s intravenoznom i peroralnom primjenom 11. i 12. dan.
English: Treatment should be continued until skin scrapings are negative on at least two consecutive occasions one month apart.
Croatian: Liječenje treba nastaviti sve dok testovi strugotina kože nisu negativni, najmanje dva uzastopna puta, u roku od mjesec dana.
English: The veterinary medicinal product should be administered at a dose of 2-4 mg/kg bodyweight in accordance with the following table:
Croatian: Veterinarsko-medicinski proizvod treba davati u dozi 2 - 4 mg/kg tjelesne težine u skladu sa sljedećom tablicom:
English: During clinical field trials, no interactions between Simparica chewable tablets for dogs and routinely used veterinary medicinal products were observed.
Croatian: Tijekom kliničkih terenskih ispitivanja nisu primijećene interakcije između Simparica tableta za žvakanje za pse i uobičajeno korištenih veterinarsko-medicinskih proizvoda.
English: For the treatment of demodicosis (caused by Demodex canis) the administration of a single dose once monthly for three consecutive months is efficacious and leads to a marked improvement of clinical signs.
Croatian: Za liječenje demodikoze (uzrokovane Demodex canis) učinkovita je primjena jedne doze jednom mjesečno, tri uzastopna mjeseca, koja dovodi do značajnog poboljšanja kliničkih znakova.
English: A distribution study determined that 14C-sarolaner-related residues were widely distributed to the tissues.
Croatian: Studije distribucije su utvrdile da su ostaci povezani s 14C-sarolanerom široko rasprostranjeni u tkivima.
English: For each strength, the chewable tablets are available in the following pack sizes: carton with 1 blister of 1, 3 and 6 tablets.
Croatian: Tablete za žvakanje dostupne su za svaku jačinu u sljedećim veličinama pakovanja: karton s 1 blisterom od 1¸ 3 ili 6 tableta.
English: EU/2/15/191/001-018
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE U PROMET EU/2/15/191/001-018
English: In the absence of available data, treatment of puppies less than 8 weeks of age and/or dogs less than 1.3 kg bodyweight should be based on a benefit-risk assessment by the responsible veterinarian.
Croatian: U nedostatku dostupnih podataka, liječenje štenaca mlađih od 8 tjedana starosti i lakših od 1,3 kg tjelesne težine trebalo bi bazirati na procjeni koristi/rizika od strane odgovornog veterinara.
English: In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label to the physician.
Croatian: U slučaju nehotičnog gutanja, hitno zatražiti savjet liječnika i pokazati mu naljepnicu ili uputu o veterinarsko-medicinskom proizvodu.
English: The veterinary medicinal product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD).
Croatian: Veterinarsko-medicinski proizvod može se koristiti kao dio strategije liječenja u kontroli alergijskog dermatitisa uzrokovanih buhama.
English: The safety of the veterinary medicinal product has not been established during pregnancy and lactation or in animals intended for breeding.
Croatian: Neškodljivost veterinarsko-medicinskog proizvoda nije utvrđena za vrijeme graviditeta, laktacije ili u životinja namijenjenim za parenje.
English: Use appropriate combination of available strengths to achieve the recommended dose of 2-4 mg/kg.
Croatian: Upotrijebite odgovarajuću kombinaciju raspoloživih jačina tableta da bi postigli preporučenu dozu od 2-4 mg/kg tjelesne težine.
English: Hypromellose acetate succinate, medium grade Lactose monohydrate
Croatian: Hipromeloza acetat sukcinat, srednje kvaliteteLaktoza monohidrat
English: Sarolaner was dose proportional in Beagle dogs when dosed from the intended use dose of 2-4 mg/kg, to 20 mg/kg.
Croatian: Sarolaner je bio razmjeran dozi kod pasa pasmine Beagle, kod doziranja propisane doze 2 do 4 mg/kg do doze 20 mg/kg tjelesne težine.
English: For the treatment of flea infestations (Ctenocephalides felis and Ctenocephalides canis).
Croatian: Za liječenje infestacije buhama (Ctenocephalides felis i Ctenocephalides canis).
English: The accidental ingestion of the product may potentially result in adverse effects, such as transient excitatory neurological signs.
Croatian: Slučajno gutanje proizvoda može dovesti do neželjenih učinaka, kao što su prolazni neurološki simptomi (ekscitacija).
English: PACKAGE LEAFLET: Simparica chewable tablets for dogs
Croatian: UPUTA O VMP: Simparica tablete za žvakanje za pse
English: The veterinary medicinal product has immediate and persistent tick killing activity for at least 5 weeks.
Croatian: Veterinarsko-medicinski proizvod ima trenutno i postojano djelovanje ubijanja krpelja najmanje 5 tjedana.
English: In a margin of safety study, the veterinary medicinal product was administered orally to 8 week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum exposure dose of 4 mg/kg at 28 day intervals for 10 doses.
Croatian: U granicama istraživanja neškodljivosti, veterinarsko-medicinski proizvod primjenjivao se peroralno štencima starim 8 tjedana pasmine Beagle u dozi 0, 1, 3 i 5 puta većoj od najveće preporučene doze, (4 mg/kg tjelesne težine) kroz 28 dana u 10 doza.
English: Mottled brown coloured, square shaped chewable tablets with rounded edges.
Croatian: Tablete za žvakanje obojene šareno smeđom bojom, kvadratnog oblika sa zaobljenim rubovima.
English: EU/2/15/191/011 (40 mg, 3 tablets) EU/2/15/191/012 (40 mg, 6 tablets) EU/2/15/191/013 (80 mg, 1 tablet) EU/2/15/191/014 (80 mg, 3 tablets) EU/2/15/191/015 (80 mg, 6 tablets) EU/2/15/191/016 (120 mg, 1 tablet) EU/2/15/191/017 (120 mg, 3 tablets) EU/2/15/191/018 (120 mg, 6 tablets)
Croatian: EU/2/15/191/011 (40 mg, 3 tablete) EU/2/15/191/012 (40 mg, 6 tableta) EU/2/15/191/013 (80 mg, 1 tableta) EU/2/15/191/014 (80 mg, 3 tablete) EU/2/15/191/015 (80 mg, 6 tableta) EU/2/15/191/016 (120 mg, 1 tableta) EU/2/15/191/017 (120 mg, 3 tablete) EU/2/15/191/018 (120 mg, 6 tableta)
English: The veterinary medicinal product kills newly emerged fleas on the dogs before they can lay eggs and therefore it prevents environmental flea contamination in areas to which the dog has access.
Croatian: Veterinarsko-medicinski proizvod ubija buhe koje dođu na psa prije nego što stignu izvaliti jajašca, te na taj način sprječava kontaminaciju buhama u područjima u kojima pas ima pristup.
English: The veterinary medicinal product has immediate and persistent flea killing activity against new infestations for at least 5 weeks.
Croatian: Veterinarsko medicinski proizvod ima trenutni i postojani učinak ubijanja buha protiv novih infestacija najmanje 5 tjedana.
English: Sarolaner is well tolerated in Collies with a deficient multidrug-resistance-protein 1 (MDR1 -/-) following single oral administration at 5 times the recommended dose.
Croatian: Collies s nedovoljnim MDR 1-/- (multidrug-resistance-protein) dobro su podnijeli sarolaner prilikom jednokratne peroralne primjene 5 puta veće doze od preporučene.
English: Mild and transient gastrointestinal signs such as vomiting and diarrhoea, transient neurological disorders such as tremor, ataxia or convulsion and systemic disorders such as lethargy, anorexia/inappetence may occur in very rare cases.
Croatian: U vrlo rijetkim slučajevima mogu se pojaviti blagi i prolazni gastrointestinalni simptomi kao što su povraćanje i proljev, prolazni neurološki poremećaji kao što su tremor, ataksija ili konvulzija i sustavni poremećaji kao što su letargija, anoreksija/inapetencija.
English: EU/2/15/191/001 (5 mg, 1 tablet) EU/2/15/191/002 (5 mg, 3 tablets) EU/2/15/191/003 (5 mg, 6 tablets) EU/2/15/191/004 (10 mg, 1 tablet) EU/2/15/191/005 (10 mg, 3 tablets) EU/2/15/191/006 (10 mg, 6 tablets) EU/2/15/191/007 (20 mg, 1 tablet) EU/2/15/191/008 (20 mg, 3 tablets) EU/2/15/191/009 (20 mg, 6 tablets) EU/2/15/191/010 (40 mg, 1 tablet)
Croatian: EU/2/15/191/001 (5 mg, 1 tableta) EU/2/15/191/002 (5 mg, 3 tablete) EU/2/15/191/003 (5 mg, 6 tableta) EU/2/15/191/004 (10 mg, 1 tableta) EU/2/15/191/005 (10 mg, 3 tablete) EU/2/15/191/006 (10 mg, 6 tableta) EU/2/15/191/007 (20 mg, 1 tableta) EU/2/15/191/008 (20 mg, 3 tablete) EU/2/15/191/009 (20 mg, 6 tableta) EU/2/15/191/010 (40 mg, 1 tableta)
English: Simparica tablets are chewable and palatable and readily consumed by dogs when offered by the owner.
Croatian: Tablete Simparica su ukusne za žvakanje zato ih psi rado uzimaju od vlasnika.
English: For ticks (I. ricinus), the onset of efficacy is within 12 hours of attachment during the 28 day period after product administration.
Croatian: Kod krpelja (I. ricinus) početak učinkovitosti veterinarsko-medicinskog proizvoda je unutar 12 sati od primjene proizvoda u trajanju od 28 dana.
English: Each tablet contains:
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Svaka tableta sadržava:
English: Sarolaner is highly bound to plasma proteins and might compete with other highly bound drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and the cumarin derivative warfarin.
Croatian: Sarolaner se čvrsto veže za proteine plazme te se može nadmetati s drugim snažno proizvodima koji se vežu na proteine plazme, kao što su nesteroidni protuupalni lijekovi (NSPUL) i derivati kumarin varfarina.
English: 1 tablet 3 tablets 6 tablets
Croatian: 6 tableta
English: In laboratory safety studies, no interactions were observed when sarolaner was co-administered with milbemycin oxime, moxidectin and pyrantel pamoate.
Croatian: U laboratorijskim ispitivanjima neškodljivosti nisu primijećene interakcije prilikom istovremene upotrebe sarolanera i milbemicin oksima, moksidektina i pirantel pamoata (učinkovitost nije istražena u ovim studijima).
English: For optimal control of tick and fleas infestations, the veterinary medicinal product should be administered at monthly intervals and continue throughout the flea and/or tick season based on local epidemiological situations.
Croatian: Za optimalnu kontrolu infestacije buhama i krpeljima, veterinarsko-medicinski proizvod treba davati na mjesečnoj bazi.
English: For fleas, the onset of efficacy is within 8 hours of attachment during the 28 day period after product administration.
Croatian: Kod buha početak učinkovitosti veterinarsko-medicinskog proizvoda je unutar 8 sati od primjene proizvoda, u trajanju od 28 dana.
English: Simparica 5 mg chewable tablets for dogs 1.3-2.5 kg Simparica 10 mg chewable tablets for dogs >2.5-5 kg Simparica 20 mg chewable tablets for dogs >5-10 kg Simparica 40 mg chewable tablets for dogs >10-20 kg Simparica 80 mg chewable tablets for dogs >20-40 kg Simparica 120 mg chewable tablets for dogs >40-60 kg
Croatian: Simparica 5 mg tablete za žvakanje za pse 1,3 - 2,5 kg Simparica 10 mg tablete za žvakanje za pse > 2,5 - 5 kg Simparica 20 mg tablete za žvakanje za pse > 5 - 10 kg Simparica 40 mg tablete za žvakanje za pse > 10 - 20 kg Simparica 80 mg tablete za žvakanje za pse > 20 - 40 kg Simparica 120 mg tablete za žvakanje za pse > 40 - 60 kg
English: Simparica 5 mg chewable tablets for dogs 1.3-2.5 kg Simparica 10 mg chewable tablets for dogs >2.5-5 kg Simparica 20 mg chewable tablets for dogs >5-10 kg Simparica 40 mg chewable tablets for dogs >10-20 kg Simparica 80 mg chewable tablets for dogs >20-40 kg Simparica 120 mg chewable tablets for dogs >40-60 kg sarolaner
Croatian: Simparica 5 mg tablete za žvakanje za pse 1,3 - 2,5 kg Simparica 10 mg tablete za žvakanje za pse > 2,5 - 5 kg Simparica 20 mg tablete za žvakanje za pse > 5 - 10 kg Simparica 40 mg tablete za žvakanje za pse > 10 - 20 kg Simparica 80 mg tablete za žvakanje za pse > 20 - 40 kg Simparica 120 mg tablete za žvakanje za pse > 40 - 60 kg sarolaner
English: Glucose, liquid (81.5% solids) Spray dried pork liver powder Hydrolysed vegetable protein Gelatin type A
Croatian: Glukoza, tekućina (81,5% krute tvari)
English: Chewable tablets
Croatian: Simparica tablete za žvakanje
English: Sodium starch glycolate Silica, colloidal anhydrous Magnesium stearate
Croatian: Silicij, koloidni bezvodni
English: 250 tablets 30 tablets
Croatian: 250 tableta 30 tableta
English: 80 mg, 25 mg 40 mg, 12.5 mg
Croatian: 80 mg, 25 mg 40 mg, 12.5 mg spremnik s tabletama (HDPE) blister (alu/alu)
English: Further information on Orencia can be found on the Agency's website: ema.europa.eu/medicines/human/EPAR/orencia.
Croatian: Više informacija o lijeku Orencia nalazi se na internetskim stranicama Agencije: ema.europa.eu/medicines/human/EPAR/orencia.
English: Around three-quarters of the patients were also taking methotrexate.
Croatian: Otprilike tri četvrtine bolesnika uzimale su i metotreksat.
English: Orencia received a marketing authorisation valid throughout the EU on 21 May 2007.
Croatian: Lijek Orencia dobio je odobrenje za stavljanje u promet koje je na snazi u EU-a od 21. svibnja 2007.
English: If Orencia has not worked within 6 months, the doctor should consider if treatment should continue.
Croatian: Ako Orencia ne djeluje unutar šest mjeseci, liječnik treba razmotriti treba li nastaviti s liječenjem.
English: What measures are being taken to ensure the safe and effective use of Orencia?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Orencia?
English: The dose depends on the patient's weight.
Croatian: Doza lijeka ovisi o tjelesnoj težini bolesnika.
English: The main measure of effectiveness was a reduction in symptoms of at least 20% after 24 weeks of treatment.
Croatian: Glavno mjerilo učinkovitosti bilo je ublažavanje simptoma za barem 20 % nakon 24 tjedna liječenja.
English: Other information about Orencia
Croatian: Ostale informacije o lijeku Orencia
English: What is Orencia and what is it used for?
Croatian: Što je Orencia i za što se primjenjuje?
English: In this case it should be followed by an injection under the skin the next day.
Croatian: U tom slučaju sljedećeg dana treba dati injekciju pod kožu.
English: Side effects reported with Orencia are carefully evaluated and any necessary action taken to protect patients.
Croatian: Nuspojave prijavljene za lijek Orencia pažljivo se procjenjuju i poduzimaju se potrebne mjere za zaštitu bolesnika.
English: Orencia is a medicine that is often used in combination with methotrexate (a medicine that acts on the immune system) to treat the following diseases:
Croatian: Orencia je lijek koji se često primjenjuje u kombinaciji s metotreksatom (lijekom koji djeluje na imunosni sustav) za liječenje sljedećih bolesti:
English: When given by infusion into a vein, Orencia is given every 2 weeks for the first 3 doses, and then every 4 weeks.
Croatian: Ako se daje infuzijom u venu, prve tri doze lijeka Orencia daju se svaka dva tjedna, a nakon toga svaka četiri tjedna.
English: By attaching to signal molecules called CD80 and CD86, abatacept stops them activating the T cells, helping to reduce the inflammation and other symptoms of the diseases.
Croatian: Vezivanjem na signalne molekule naziva CD80 i CD86 abatacept ih sprječava u aktiviranju T-stanica, što pomaže ublažiti upalu i druge simptome bolesti.
English: When injected under the skin, Orencia is given once a week.
Croatian: Ako se daje injekcijom pod kožu, Orencia se daje jednom tjedno.
English: Patients taking Orencia also had a greater improvement in physical function after six months.
Croatian: U bolesnika koji su primali lijek Orencia došlo je i do većeg poboljšanja fizičke funkcije nakon šest mjeseci.
English: As for all medicines, data on the use of Orencia is continuously monitored.
Croatian: Kao i za sve lijekove, podatci o primjeni lijeka Orencia kontinuirano se prate.
English: T cells are activated when signal molecules attach to receptors on the cells.
Croatian: T-stanice aktiviraju se kada se signalne molekule vežu na receptore stanica.
English: What are the risks associated with Orencia?
Croatian: Koji su rizici povezani s lijekom Orencia?
English: After being trained and with the agreement of their doctor, patients or carers may inject the medicine themselves.
Croatian: Nakon što prođu obuku i uz suglasnost svojeg liječnika, bolesnici si mogu sami davati lijek injekcijom.
English: An overview of Orencia and why it is authorised in the EU
Croatian: Pregled informacija o lijeku Orencia i zašto je odobren u EU-u
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Orencia have also been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Orencia nalaze se također u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: Why is Orencia authorised in the EU?
Croatian: Zašto je lijek Orencia odobren u EU-u?
English: Patients who receive Orencia are given a special alert card explaining that it must not be used in patients with certain infections and instructing patients to contact their doctor immediately if they develop an infection during treatment with Orencia.
Croatian: Bolesnicima koji primaju lijek Orencia izdaje se posebna kartica s upozorenjima u kojoj je objašnjeno da ga bolesnici s određenim infekcijama ne smiju uzimati i uputama o tome da se odmah obrate svojem liječniku ako razviju infekciju tijekom liječenja lijekom Orencia.
English: • highly active and progressive rheumatoid arthritis, used in combination with methotrexate in adults who have not previously been treated with methotrexate;
Croatian: • izrazito aktivnog i progresivnog reumatoidnog artritisa, u kombinaciji s metotreksatom u odraslih osoba koje prethodno nisu liječene metotreksatom;
English: Orencia must not be used in patients with severe and uncontrolled infections, such as sepsis (when bacteria and their toxins circulate in the blood and start to damage the organs) or ‘opportunistic' infections (infections seen in patients with a weakened immune system).
Croatian: Orencia se ne smije primjenjivati u bolesnika s teškim i nekontroliranim infekcijama, poput sepse (pri čemu bakterije i njihovi toksini cirkuliraju krvotokom i počinju oštećivati organe) ili „oportunističkih” infekcija (infekcije zabilježene u bolesnika oslabljenog imunosnog sustava).
English: The Agency also concluded that Orencia could be a valuable option in the treatment of polyarticular juvenile idiopathic arthritis.
Croatian: Agencija je također zaključila da bi lijek Orencia mogao biti korisna opcija u liječenju poliartikularnog juvenilnog idiopatskog artritisa.
English: Children between 2 and 6 years should only use Orencia pre-filled syringes.
Croatian: U djece u dobi između dvije i šest godina Orencia se treba primjenjivati samo napunjenim štrcaljkama.
English: The main measures of effectiveness were the reduction in symptoms of arthritis after treatment, as well as physical function (the ability to carry out everyday tasks) and the amount of damage to the joints (assessed using X-rays).
Croatian: Glavno mjerilo učinkovitosti bilo je ublažavanje simptoma artritisa nakon terapije, kao i fizička funkcija (sposobnost izvršavanja svakodnevnih poslova) i težina oštećenja zglobova (ocijenjeno rendgenskom snimkom).
English: In rheumatoid arthritis, if the patient is receiving Orencia for the first time, the first dose can be given by infusion.
Croatian: Ako bolesnik s reumatoidnim artritisom prvi put dobiva lijek Orencia, prva doza može se dati infuzijom.
English: All patients received Orencia for 4 months, after which the 122 whose condition had improved on Orencia were either switched to placebo or continued receiving Orencia.
Croatian: Svi bolesnici primali su lijek Orencia tijekom četiri mjeseca, nakon čega je 122 bolesnika kod kojih se stanje poboljšalo prebačeno na placebo ili su nastavili primati lijek Orencia.
English: The study included 259 patients who had previously been treated with a TNF alpha blocker.
Croatian: Ispitivanjem je bilo obuhvaćeno 259 bolesnika koji su prethodno liječeni TNF-alfa blokatorom.
English: The most common side effects with Orencia (seen in more than 1 patient in 10) are upper respiratory tract infections (nose and throat infection).
Croatian: Najčešće su nuspojave lijeka Orencia (zabilježene u više od 1 na 10 osoba) infekcije gornjih dišnih putova (infekcija nosa i grla).
English: Orencia can only be obtained with a prescription, and treatment with it should be started and supervised by a specialised doctor with experience in the diagnosis and treatment of rheumatoid arthritis or polyarticular juvenile idiopathic arthritis.
Croatian: Orencia se izdaje samo na liječnički recept, a liječenje mora započeti i nadzirati liječnik specijalist s iskustvom u dijagnosticiranju i liječenju reumatoidnog artritisa ili poliartikularnog juvenilnog idiopatskog artritisa.
English: In polyarticular juvenile idiopathic arthritis, Orencia infusion was found effective in one main study involving patients aged between 6 and 17 years whose previous treatment had not worked.
Croatian: Kod poliartikularnog juvenilnog idiopatskog artritisa, infuzija lijeka Orencia pokazala se učinkovitom u jednom glavnom ispitivanju koje je obuhvaćalo bolesnike u dobi između šest i 17 godina kod kojih prethodno liječenje nije bilo djelotvorno.
English: The first two studies included 991 patients in whom methotrexate had not worked well enough.
Croatian: Prva dva ispitivanja obuhvatila su 991 bolesnika u kojih metotreksat nije bio dovoljno djelotvoran.
English: Subsequently, it is injected under the skin once a week.
Croatian: Lijek se nakon toga daje injekcijom pod kožu jednom tjedno.
English: How does Orencia work?
Croatian: Kako djeluje Orencia?
English: For more information about using Orencia, see the package leaflet or contact your doctor or pharmacist.
Croatian: Više informacija o primjeni lijeka Orencia pročitajte u uputi o lijeku, odnosno obratite se liječniku ili ljekarniku.