FrancophonIA/ELRC3.0 huggingface dataset:
English: • If you need to stick the patch to a hairy area of skin, you must shave the area at least 3 days before sticking the patch there.
Slovenian: • Če morate obliž nalepiti na poraščeno mesto na koži, morate to mesto obriti vsaj tri dni pred namestitvijo obliža.
English: Depending on the patient's response, not all of the following dose steps may be required or additional higher doses may be needed after week 4, which are not covered by this package.
Slovenian: Odvisno od bolnikovega odziva morda ne bodo potrebni vsi koraki povečevanja odmerjanja ali pa bodo po 4. tednu potrebni dodatni večji odmerki, ki jih komplet ne vsebuje.
English: Within the system organ classes, adverse reactions are listed under headings of frequency (number of patients expected to experience the reaction), using the following categories: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Slovenian: V organskih sistemih so neželeni učinki razvrščeni po pogostnosti (število bolnikov, pri katerih se pričakuje, da bodo imeli reakcijo) takole: zelo pogosti (≥ 1/10); pogosti (≥ 1/100 do < 1/10); občasni (≥ 1/1.000 do < 1/100); redki (≥ 1/10.000 do < 1/1.000); zelo redki (< 1/10.000); neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: • abnormal thinking or behaviour.
Slovenian: • nenormalno mišljenje ali vedenje.
English: Following this procedure, rebound (worsening of symptoms beyond initial intensity after discontinuation of treatment) has not been observed.
Slovenian: Ob upoštevanju navedenega postopka ni bilo opaziti poslabšanja stanja (poslabšanje simptomov z intenziteto, višjo od začetne, po prekinitvi zdravljenja).
English: • Always check that the patch has not fallen off after activities such as bathing, showering or exercising.
Slovenian: • Vedno preverite ali se je obliž odlepil po aktivnostih kot so kopanje, prhanje ali telovadba.
English: BOX OF 7 [28] [30] PATCHES
Slovenian: ŠKATLA S 7 [28] [30] [OBLIŽI
English: • delusions and hallucinations (seeing or hearing things that are not real)
Slovenian: • blodnje in halucinacije (videnje ali slišanje stvari, ki niso resnične)
English: If it is necessary to discontinue rotigotine, this should be done gradually to prevent neuroleptic malignant syndrome.
Slovenian: Če je prekinitev zdravljenja z rotigotinom nujna, jo je treba izvesti postopoma, da se prepreči nevroleptični maligni sindrom.
English: • aggressive behaviour
Slovenian: • agresivno vedenje
English: In long-term clinical studies with rotigotine, the majority of augmentation episodes were seen in the first and second years of treatment.
Slovenian: V dolgoročnih kliničnih študijah z rotigotinom, so večino epizod avgmentacije opazili v prvem in drugem letu zdravljenja.
English: If you experience such symptoms either before or after beginning treatment with Leganto, contact your doctor as your treatment may need to be adjusted.
Slovenian: Če se pri vas pojavijo takšni simptomi pred ali po začetku zdravljenja z zdravilom Leganto, se posvetujte z zdravnikom, saj bo vaše zdravljenje morda treba prilagoditi.
English: • feeling agitated, disorientated, confused or paranoid
Slovenian: • občutek vznemirjenosti, dezorientiranosti, zmedenosti ali paranoje
English: Prescribers should continually reassess patients for drowsiness or sleepiness, as patients may not acknowledge drowsiness or sleepiness until directly questioned.
Slovenian: Zdravniki morajo redno ocenjevati dremavost ali zaspanost bolnikov, kajti bolniki dremavosti ali zaspanosti morda ne bodo omenili, dokler ne bodo neposredno vprašani.
English: Leganto is available in the following pack-sizes:
Slovenian: Zdravilo Leganto je na voljo v naslednjih velikostih pakiranja:
English: You may have to use more than one patch to reach your dose, as prescribed by your doctor.
Slovenian: Morda boste morali uporabiti več kot en obliž, da dosežete svoj odmerek, ki vam ga je predpisal zdravnik.
English: • If you have forgotten to change the patch at your usual time, change it as soon as you remember.
Slovenian: • Če ste pozabili zamenjati obliž ob vašem običajnem času, ga zamenjajte takoj, ko se spomnite.
English: In this study, the majority of augmentation episodes occurred in the first and second years of treatment.
Slovenian: Večina epizod avgmentacije v tej študiji se je pojavila v prvem in drugem letu zdravljenja.
English: Comparable skin tolerability was reported for both formulations.
Slovenian: Za obe formulaciji so poročali o primerljivem prenašanju.
English: Rotigotine is metabolised to a great extent.
Slovenian: Rotigotin se presnavlja v veliki meri.
English: Contact your doctor if you notice signs of an allergic reaction - these can include swelling of the face, tongue or lips.
Slovenian: Posvetujte se z zdravnikom, če opazite znake alergijske reakcije - kot so otekanje obraza, jezika ali ustnic.
English: • you need ‘cardioversion' (specific treatment for abnormal heart beat).
Slovenian: • potrebujete ‘kardioverzijo' (specifično zdravljenje nenormalnega srčnega ritma)
English: 4 mg of Leganto every day may be an effective dose for some patients.
Slovenian: 4 mg zdravila Leganto vsak dan je lahko učinkovit odmerek za nekatere bolnike.
English: • Do not touch the sticky side of the patch with your fingers.
Slovenian: • Lepljive strani obliža se ne dotikajte s prsti.
English: It belongs to a group of medicines called ‘dopamine agonists'.
Slovenian: Spada v skupino zdravil, imenovanih ‘dopaminski agonisti'.
English: Two additional pivotal trials (SP650DB and SP515) were conducted in patients who were receiving concomitant levodopa therapy.
Slovenian: Dve dodatni ključni preskušanji (SP650DB in SP515) so opravili pri bolnikih, ki so prejemali sočasno zdravljenje z L-dopo.
English: A further multinational double-blind study (SP889) was conducted in 287 patients with early or advanced stages of Parkinson's disease who had unsatisfactory early morning motor symptom control.
Slovenian: Naslednja večnacionalna dvojno slepa študija (SP889) je bila opravljena z 287 bolniki v zgodnji ali napredovali fazi Parkinsonove bolezni, ki so imeli zgodaj zjutraj nezadovoljivo kontrolo nad motoriko.
English: The effects of rotigotine on reproduction have been investigated in rats, rabbits and mice.
Slovenian: Učinke rotigotina na razmnoževanje so raziskovali pri podganah, kuncih in miših.
English: Differences in bioavailability of rotigotine ranged from 2% (upper arm versus flank) to 46% (shoulder versus thigh).
Slovenian: Razlike biološke uporabnosti rotigotina so se spreminjale od 2 % (nadlaht v primerjavi z bokom) do 46 % (rama v primerjavi s stegnom).
English: You should take Leganto 2 mg for 7 days (e.g. if you start on a Sunday, switch to the next dose on the following Sunday.).
Slovenian: Zdravilo Leganto 2 mg jemljite 7 dni (npr. če začnete v nedeljo, preidite na naslednji odmerek naslednjo nedeljo).
English: Following application, rotigotine is continuously released from the transdermal patch and absorbed through the skin.
Slovenian: Po aplikaciji se rotigotin neprekinjeno sprošča iz transdermalnega obliža in absorbira skozi kožo.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Slovenian: • Načrt za obvladovanje tveganja (RMP) Imetnik dovoljenja za promet z zdravilom bo izvedel zahtevane farmakovigilančne aktivnosti in ukrepe, podrobno opisane v sprejetem RMP, predloženem v modulu 1.8.2 dovoljenja za promet z zdravilom, in vseh nadaljnjih posodobitvah RMP.
English: The patch should be pressed down firmly with the palm of the hand for about 30 seconds, so that it sticks well.
Slovenian: Obliž približno 30 sekund trdno pritiskamo z dlanjo, da se dobro prilepi.
English: • you may feel very sleepy or fall asleep suddenly - see ‘Driving and using machines' in section 2.
Slovenian: • lahko postanete zelo zaspani ali nenadno zaspite - glejte 'Vpliv na sposobnost upravljanja vozil in strojev' v poglavju 2.
English: Other medicines and Leganto
Slovenian: Druga zdravila in zdravilo Leganto
English: Each patch is packed in a sachet and should be applied directly after the sachet has been opened.
Slovenian: Vsak obliž je pakiran v zaščitno vrečko, uporabiti pa ga je treba takoj po odprtju zaščitne vrečke.
English: The adjusted mean difference was -6.5 points (CI95% -8.7; -4.4, p <0.0001).
Slovenian: Prilagojena srednja razlika je bila -6,5 točk (CI95% -8,7 - -4,4, p<0,0001).
English: • paranoia
Slovenian: • paranoja
English: In isolated cases “sudden onset of sleep” occurred while driving and resulted in motor vehicle accidents (see also sections 4.4 and 4.7).
Slovenian: V posameznih primerih je nastopil "nenaden spanec" med vožnjo, zaradi katerega so se zgodile prometne nesreče(glejte tudi poglavji 4.4 in 4.7).
English: The efficacy of rotigotine was evaluated in 5 placebo-controlled trials with more than 1,400 patients with idiopathic Restless Legs Syndrome (RLS).
Slovenian: Učinkovitost rotigotina so ocenili v petih s placebom kontroliranih študijah z več kot 1.400 bolniki z idiopatičnim sindromom nemirnih nog (RLS - Restless Legs Syndrome).
English: If you have to stop taking this medicine, see ‘If you stop using Leganto' in section 3.
Slovenian: Če morate prekiniti uporabo zdravila, glejte, 'Če ste prenehali uporabljati zdravilo Leganto' v poglavju 3.
English: Leganto may potentiate the dopaminergic adverse reaction of L-dopa and may cause and/or exacerbate pre-existing dyskinesia, as described with other dopamine agonists.
Slovenian: Zdravilo Leganto lahko okrepi dopaminergične neželene učinke L-dope ter povzroči in/ali poslabša obstoječo diskinezijo, kot je opisano pri drugih agonistih dopamina.
English: The effectiveness of rotigotine in the treatment of the signs and symptoms of idiopathic Parkinson's disease was evaluated in a multinational drug development program consisting of four pivotal, parallel, randomized, double-blind placebo controlled studies and three studies investigating specific aspects of Parkinson's disease.
Slovenian: Učinkovitost rotigotina pri zdravljenju znakov in simptomov idiopatične Parkinsonove bolezni so ocenili v večnacionalnem programu za razvoj zdravila, sestavljenem iz štirih ključnih, vzporednih, randomiziranih, dvojno slepih s placebom nadzorovanih kliničnih študij in treh študij, kjer so ocenjevali specifične vidike Parkinsonove bolezni.
English: • Do not stick Leganto on the same area of skin twice within 14 days.
Slovenian: • Ne lepite obliža zdravila Leganto ponovno na isto mesto prej kot v 14 dneh.
English: If you have used a different patch (e.g. Leganto 4 mg/24 h instead of Leganto 2 mg/24 h) than your doctor told you to, contact your doctor or hospital for advice immediately, and follow their advice on changes of patches.
Slovenian: Če ste uporabili drugačen obliž (npr. Leganto 4 mg/24 h, namesto Leganto 2 mg/24 h), kot vam je predpisal zdravnik, takoj obvestite svojega zdravnika ali bolnišnico in sledite njihovemu navodilu za odstranitev obližev.
English: A sudden stop could lead to a medical condition called ‘neuroleptic malignant syndrome' which could be life-threatening.
Slovenian: Nenadna prekinitev lahko vodi v razvoj ‘malignega nevroleptičnega sindroma', ki je lahko življensko nevaren.
English: The clearance of rotigotine after transdermal administration is approximately 10 l/min and its overall elimination half-life is 5 to 7 hours.
Slovenian: Po transdermalni uporabi je očistek rotigotina približno 10 l/min, celokupni razpolovni čas izločanja pa 5 do 7 ur.
English: • difficulty falling asleep, sleep disorder, difficulty sleeping, nightmare, unusual dreams
Slovenian: • težava zaspati, motnje spanja, težave s spanjem, nočne more, nenavadne sanje
English: If you have any unpleasant reactions, contact your doctor.
Slovenian: Če imate kakršne koli neprijetne reakcije, se posvetujte s svojim zdravnikom.
English: • Before opening the sachet decide where you are going to stick this new patch and check you have removed any old patch.
Slovenian: • Pred odprtjem zaščitne vrečke se odločite kam boste nalepili nov obliž in preverite, če ste odstranili stari obliž.
English: Although these adverse reactions are believed to be related to the ergoline structure of these compounds, whether other, nonergot derived dopamine agonists can cause them is unknown.
Slovenian: Čeprav naj bi bile te neželene reakcije povezane z ergolinsko strukturo teh spojin, ni znano, ali jih povzročajo tudi drugi agonisti dopamina, ki niso pridelani iz ergota.
English: Ophthalmologic monitoring is recommended at regular intervals or if vision abnormalities occur.
Slovenian: Okulistični nadzor se priporoča v rednih časovnih presledkih ali če se pojavijo motnje vida.
English: If you forget to change the patch at your usual time
Slovenian: Če pozabite zamenjati obliž ob običajnem času
English: • unusual urges or cravings which you cannot resist and that could harm yourself or others
Slovenian: • nenavadne težnje ali želje, ki se jim ne morete upreti in bi lahko škodovale vam ali drugim
English: In isolated cases, people have fallen asleep while driving and this has caused accidents.
Slovenian: V posameznih primerih so vozniki med vožnjo zaspali, kar je povzročilo nesreče.
English: • You may have to use more than one patch to reach your dose, as prescribed by your doctor.
Slovenian: • Morda boste morali uporabiti več kot en obliž, da dosežete svoj odmerek, ki vam ga je predpisal zdravnik.
English: Animal studies do not indicate any teratogenic effects in rats and rabbits, but embryo-toxicity was observed in rats and mice at materno-toxic doses (see section 5.3).
Slovenian: Študije na živalih ne kažejo kakršnihkoli teratogenih učinkov pri podganah in kuncih, vendar so pri podganah in miših opazili toksične učinke na zarodek pri odmerkih, ki so bili toksični za mater (glejte poglavje 5.3).
English: If the patient forgets to apply the patch at the usual time of the day or if the patch becomes detached, another patch should be applied for the remainder of the day.
Slovenian: Če bolnik pozabi namestiti obliž ob običajnem času ali če se obliž odlepi, mora za preostanek tega dneva namestiti nov obliž.
English: If a Parkinson's disease patient is insufficiently controlled while on treatment with rotigotine switching to another dopamine agonist might provide additional benefit (see section 5.1)
Slovenian: Če je odziv bolnika s Parkinsonovo boleznijo na zdravljenje z rotigotinom nezadosten, lahko prehod na drugi agonist dopamina ponuja dodaten uspeh zdravljenja (glejte poglavje 5.1).
English: If application site reactions occur which last for more than a few days or are persistent, if there is an increase in severity, or if the skin reaction spreads outside the application site, an assessment of the risk/benefit balance for the individual patient should be conducted.
Slovenian: Če se pojavijo reakcije na mestu aplikacije, ki trajajo več kot nekaj dni ali ne izginejo, če se slabšajo ali če se razširijo zunaj mesta uporabe, je treba oceniti razmerje koristi in tveganja zdravljenja za tega bolnika.
English: In repeated dose and long-term toxicity studies, the major effects were associated with the dopamine agonist related pharmacodynamic effects and the consequent decrease of prolactin secretion.
Slovenian: Pri študijah ponavljajočih se odmerkov in dolgotrajne toksičnosti je bila večina učinkov povezana s farmakodinamiko agonistov dopamina in posledičnim zmanjšanjem izločanja prolaktina.
English: Co-administration of rotigotine (3 mg/24 h) did not affect the pharmacodynamics and pharmacokinetics of oral contraceptives (0.03 mg ethinylestradiol, 0.15 mg levonorgestrel).
Slovenian: Sočasna uporaba rotigotina (3 mg/24 h) ni vplivala na farmakodinamiko in farmakokinetiko peroralnih kontraceptivov (0,03 mg etinilestradiol, 0,15 mg levonorgestrel).
English: (eating more food than normal and more than is needed to satisfy your hunger).
Slovenian: (uživanje več hrane kot običajno in več kot je potrebno za potešitev lakote).
English: Dopamine agonists are known to impair the systemic regulation of the blood pressure resulting in postural/orthostatic hypotension.
Slovenian: Znano je, da agonisti dopamina okvarijo sistemsko regulacijo krvnega tlaka, kar povzroča posturalno/ortostatsko hipotenzijo.
English: Neuroleptic malignant syndrome
Slovenian: Maligni nevroleptični sindrom
English: It is thought that rotigotine may exert its activity mainly via dopamine receptors.
Slovenian: Domneva se, da bi lahko rotigotin učinkoval zlasti preko dopaminergičnih receptorjev.
English: This effect was not confirmed in vivo in the Mouse Micronucleus Test in the rat Unscheduled DNA Synthesis (UDS) test.
Slovenian: Tega učinka niso potrdili in vivo pri testu mikronukleusa pri miših in pri testu nenačrtovane sinteze DNA (UDS - Unscheduled DNA Synthesis) pri podganah.
English: What you need to know before you use Leganto
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Leganto
English: Patients being treated with rotigotine and presenting with somnolence and/or sudden sleep episodes must be informed not to drive or engage in activities (e.g. operating machines) where impaired alertness may put themselves or others at risk of serious injury or death until such recurrent episodes and somnolence have resolved (see also sections 4.4 and 4.5).
Slovenian: Bolnike, ki se zdravijo z rotigotinom in pri katerih se pojavita somnolenca in/ali epizode nenadnega spanca, morate opozoriti, da naj ne vozijo ali opravljajo aktivnosti (npr. upravljanje strojev), pri katerih lahko zaradi zmanjšane budnosti sebe ali druge izpostavijo povečanemu tveganju za resne poškodbe ali smrti, vse dokler taki ponavljajoči se napadi in somnolenca ne prenehajo (glejte tudi poglavji 4.4 in 4.5).
English: Co-administration of omeprazole (inhibitor of CYP2C19), in doses of 40 mg/day, had no effect on the pharmacokinetics and metabolism of rotigotine in healthy volunteers.
Slovenian: Sočasna uporaba omeprazola (inhibitor CYP2C19) v odmerkih 40 mg/dan nima nobenega vpliva na farmakokinetiko in metabolizem rotigotina pri zdravih prostovoljcih.
English: Studies in rats have shown that rotigotine and/or its metabolite(s) are excreted in breast milk.
Slovenian: Študije na podganah so pokazale, da se rotigotin in/ali njegovi presnovki izločajo v materino mleko.
English: • increased levels of creatine phosphokinase (CPK) in blood in Japanese patients (CPK is an enzyme found mainly in skeletal muscles), no information is available in other populations.
Slovenian: • zvišane vrednosti kreatin-fosfokinaze (CPK) v krvi japonskih bolnikov (CPK je encim, ki ga najdemo predvsem v skeletnih mišicah); informacije niso na voljo za druge populacije
English: This study failed to demonstrate non-inferiority of rotigotine to ropinirole.
Slovenian: V tej študiji ni bilo dokazano, da rotigotin ni inferioren glede na ropinirol.
English: Rotigotine significantly reduced the periodic limb movement index (PLMI) from 50.9 to 7.7 versus 37.4 to 32.7 for placebo (p<0.0001).
Slovenian: Rotigotin je pomembno zmanjšal indeks periodičnega gibanja udov (Periodic Limb Movement IndexPLMI) iz 50,9 na 7,7 proti 37,4 na 32,7 za placebo (p<0,0001).
English: • low blood pressure when standing up, high blood pressure
Slovenian: • nizek krvni tlak pri vstajanju, visok krvni tlak
English: In studies SP824 and SP825 conducted since the initial comparative trial, rotigotine and ropinirole at equivalent doses were shown to have comparable efficacy.
Slovenian: V študijah SP824 in SP825, ki so potekale od začetnega primerjalnega preskušanja, je bila dokazana primerljiva učinkovitost rotigotina in ropinirola pri enakih odmerkih.
English: • Bend the patch in half.
Slovenian: • Obliž prepognite na pol.
English: • Do not stick the patch on broken or damaged skin - or on skin that is red or irritated.
Slovenian: • Obliža zdravila Leganto ne uporabite na razpokani ali poškodovani koži - ali na koži, ki je pordela ali razdražena.
English: Your doctor will let you know if it is safe to keep taking these medicines while using Leganto.
Slovenian: Zdravnik vam bo svetoval, če je varno jemati ta zdravila med zdravljenjem z zdravilom Leganto.
English: • visual disturbances such as seeing colours or lights
Slovenian: • motnje vida, kot je videnje barv ali svetlobe
English: See ‘Changes to your behaviour and abnormal thinking' in section 4 for more information.
Slovenian: Za dodatne informacije glejte ‘Spremembe v vedenju in nenormalno mišljenje' v poglavju 4.
English: Regarding the functional activity at the various receptor subtypes and their distribution in the brain, rotigotine is a D2 and D3 receptor agonist acting also on D1, D4 and D5 receptors.
Slovenian: Zaradi delovanja na različnih podtipih receptorjev in njihove razporeditve v možganih je rotigotin agonist na receptorjih D2 in D3, ki deluje tudi na receptorje D1, D4 in D5.
English: • Parkinson's disease - lowered by 2 mg every other day.
Slovenian: • Parkinsonova bolezen - zmanjšati za 2 mg vsak drugi dan.
English: • metoclopramide - used to treat nausea (feeling sick) and vomiting.
Slovenian: • metoklopramid - uporablja se za zdravljenje navzeje (občutek slabosti) in bruhanja.
English: • increased levels of creatine phosphokinase (CPK) in blood in Japanese patients (CPK is an enzyme found mainly in skeletal muscles)
Slovenian: • zvišane vrednosti kreatin-fosfokinaze (CPK) v krvi japonskih bolnikov (CPK je encim, ki ga najdemo predvsem v skeletnih mišicah)
English: Do not use Leganto if:
Slovenian: Ne uporabljajte zdravila Leganto, če:
English: • increased or abnormal liver function test results
Slovenian: • povišani ali nenormalni izvidi preiskav delovanja jeter
English: • unusual urges or cravings which you cannot resist and that could harm yourself or others - the symptoms are mainly seen in patients with Parkinson's disease
Slovenian: • nenavadne težnje ali želje, ki se jim ne morete upreti in bi lahko škodovale vam ali drugim - ti simptomi so večinoma opazni pri bolnikih s Parkinsonovo boleznijo
English: Two pivotal trials (SP512 Part I and SP513 Part I) investigating the effectiveness of rotigotine in the treatment of the signs and symptoms of idiopathic Parkinson's disease were conducted in patients who were not receiving concomitant dopamine agonist therapy and were either L-dopa naïve or previous L-dopa treatment was ≤ 6 months.
Slovenian: Dve ključni preskušanji (SP512 del I in SP513 del I), pri katerih so preučevali učinkovitost rotigotina pri zdravljenju znakov in simptomov idiopatične Parkinsonove bolezni, so opravili na bolnikih, ki niso prejemali sočasnega zdravljenja z agonistom dopamina in ki bodisi niso nikoli prejemali L-dope ali katerih predhodno zdravljenje z L-dopo je trajalo ≤ 6 mesecev.
English: Application site reactions
Slovenian: Reakcije na mestu aplikacije
English: Rotigotine did not influence male fertility in rats, but clearly reduced female fertility in rats and mice, because of the effects on prolactin levels which are particularly significant in rodents.
Slovenian: Rotigotin ni vplival na plodnost podganjih samcev, vendar je očitno zmanjšal plodnost samic podgan in miši zaradi učinka na raven prolaktina, ki je pri glodavcih posebno pomembna.
English: The difference was 5.28 points and statistically significant (p<0.0001).
Slovenian: Razlika je bila 5,28 točke in je bila statistično pomembna (p<0,0001).
English: If you stop using Leganto
Slovenian: Če ste prenehali uporabljati zdravilo Leganto
English: Limited pharmacokinetic data obtained in adolescent patients with RLS (13-17 years, n=24) following treatment with multiple doses of 0.5 to 3mg/24h showed that systemic exposure to rotigotine was similar to that observed in adults.
Slovenian: Omejeni podatki o farmakokinetiki pri mladostnikih z RLS (13-17 let, n=24) pri zdravljenju z večkratnimi odmerki od 0,5 do 3 mg/24h, so pokazali podobno sistemsko izpostavljenost rotigotinu kot pri odraslih.
English: • strong impulse to gamble too much - even if this seriously affects you or your family
Slovenian: • močna želja po pretiranem hazardiranju kljub resnim osebnim ali družinskim posledicam