FrancophonIA/ELRC3.0 huggingface dataset:
English: At the end of the maintenance treatment in 92% of the subjects in the rotigotine arm, the optimal dose was the maximal dose allowed i.e. 8 mg/24 h. An improvement of 20% was seen in 52% of the subjects receiving rotigotine, 68% of the subjects receiving ropinirole and 30% of the subjects receiving placebo (Difference rotigotine versus placebo 21.7%, CI95% 11.1%; 32.4%, difference ropinirole versus placebo 38.4%, CI95% 28.1%; 48.6%, difference ropinirole versus rotigotine 16.6%, CI95% 7.6%; 25.7%).
Spanish: Al final del tratamiento de mantenimiento, en el 92% de los sujetos del grupo de rotigotina la dosis óptima fue la dosis máxima permitida, es decir, 8 mg/24 h. Se apreció una mejoría del 20% en el 52% de los sujetos tratados con rotigotina, el 68% de los tratados con ropinirol y el 30% de los tratados con placebo (diferencia entre rotigotina y placebo: 21,7%, IC95% 11,1%; 32,4%, diferencia entre ropinirol y placebo: 38,4%, IC95% 28,1%; 48,6%; diferencia entre ropinirol y rotigotina: 16,6%, IC95% 7,6%; 25,7%).
English: AST, ALT, GGT), weight increased e, heart rate increased e,
Spanish: (incluyendo AST, ALT, GGT), aumento de peso e,
English: Dosing in patients with advanced stage Parkinson's disease with fluctuations:
Spanish: Posología en pacientes con enfermedad de Parkinson en etapas iniciales:
English: The same site should not be used within 14 days.
Spanish: No se debe aplicar un parche en la misma zona antes de que hayan pasado 14 días desde la anterior aplicación.
English: Dopamine dysregulation syndromec
Spanish: Síndrome de disregulación dopaminérgicac
English: A reduction of dosage or termination of therapy should be carefully considered.
Spanish: En caso de que se produzca, debe considerarse la posibilidad de disminuir la dosis o suspender el tratamiento.
English: SACHET LABEL - WEEK 1
Spanish: ETIQUETA DEL SOBRE - SEMANA 1
English: For most patients with early stage Parkinson's disease, the right dose is reached within 3 or 4 weeks, at doses of 6 mg per day or 8 mg per day respectively.
Spanish: En la mayoría de los casos de enfermedad de Parkinson en etapas iniciales, la dosis apropiada se alcanza en 3 o 4 semanas, con dosis de 6 mg/24 h u 8 mg/24 h, respectivamente.
English: • From the second week, your daily dose may be increased by 1 mg each week until you get to the right maintenance dose for you.
Spanish: • Desde la segunda semana, la dosis diaria se aumentará en 1 mg semanalmente hasta alcanzar la dosis de mantenimiento apropiada para usted.
English: • Thigh or hip.
Spanish: • Muslo o cadera.
English: A single daily dose should be initiated at 2 mg/24 h and then increased in weekly increments of 2 mg/24 h to an effective dose up to a maximum dose of 8 mg/24 h.
Spanish: La administración debe comenzar con una única dosis diaria de 2 mg/24 h, con incrementos semanales de 2 mg/24 h, pudiéndose alcanzar una dosis efectiva máxima de 8 mg/24 h.
English: Cases of retroperitoneal fibrosis, pulmonary infiltrates, pleural effusion, pleural thickening, pericarditis and cardiac valvulopathy have been reported in some patients treated with ergot-derived dopaminergic agents.
Spanish: En algunos pacientes tratados con fármacos dopaminérgicos derivados de la ergotamina se han descrito casos de fibrosis retroperitoneal, infiltrados pulmonares, derrame pleural, engrosamiento pleural, pericarditis y valvulopatía cardiaca.
English: Peripheral oedema has been observed in clinical trials conducted in patients with RLS.
Spanish: Se ha observado edema periférico en los ensayos clínicos en pacientes con Síndrome de Piernas Inquietas.
English: Symptoms suggestive of neuroleptic malignant syndrome have been reported with abrupt withdrawal of dopaminergic therapy.
Spanish: Tras la retirada brusca del tratamiento dopaminérgico se han descrito síntomas indicativos de síndrome neuroléptico maligno.
English: • From the second week your daily dose will be increased by 2 mg each week - until you get to the right maintenance dose for you.
Spanish: • Desde la segunda semana, la dosis diaria se aumentará en 2 mg semanalmente - hasta alcanzar la dosis de mantenimiento apropiada para usted.
English: This leaflet was last revised in {MM/YYYY}
Spanish: Fecha de la última revisión de este prospecto:
English: In trials where the application sites were rotated as reflected in the instructions provided in SmPC and package leaflet, 35.7% of 830 patients using the Leganto transdermal patch, experienced application site reactions.
Spanish: En los ensayos en los que se rotó el lugar de aplicación como se indica en las instrucciones incluidas en la ficha técnica y en el prospecto del envase, el 35,7% de los 830 pacientes que usaron Leganto parche transdérmico presentó reacciones en el lugar de aplicación.
English: Each patch of 15 cm contains 6.75 mg of rotigotine.
Spanish: Cada parche de 15 cm contiene 6,75 mg de rotigotina.
English: Each patch of 30 cm contains 13.5 mg of rotigotine.
Spanish: Cada parche de 30 cm contiene 13,5 mg de rotigotina.
English: 1 transdermal patch
Spanish: 1 parche transdérmico
English: Cardiac disorders
Spanish: Tarstornos cardíacos
English: Somnolence, dizziness, headache
Spanish: Vómitos, dispepsia
English: Uncommon: may affect up to 1 in 100 people
Spanish: Poco frecuentes: pueden afectar hasta 1 de cada 100 pacientes
English: Leganto 2 mg/24 h Leganto 4 mg/24 h Leganto 6 mg/24 h Leganto 8 mg/24 h Transdermal patch
Spanish: Leganto 2 mg/24 h Leganto 4 mg/24 h Leganto 6 mg/24 h Leganto 8 mg/24 h Parche transdérmico
English: Hypertension Orthostatic hypotension
Spanish: Hipertensión Hipotensión ortostática
English: The patients were titrated to their optimal dose of rotigotine or placebo in weekly increments of 2 mg/24 h starting at 2 mg/24 h to a maximum dose of 16 mg/24 h over 8 weeks, followed by a maintenance period of 4 weeks.
Spanish: Se les ajustó la dosis de rotigotina o placebo hasta la dosis óptima en incrementos semanales de 2 mg/24 h comenzando con 2 mg/24h hasta una dosis máxima de 16 mg/24 h durante 8 semanas, seguido de un periodo de mantenimiento de 4 semanas.
English: Aggressive behaviour/ aggression b, disorientation d
Spanish: Comportamient o agresivo/agresió nb, desorientaciónd
English: The outside is tan-coloured and is imprinted with Leganto 1 mg/24 h or 3 mg/24 h.
Spanish: La parte exterior es de color tostado y lleva impresa la leyenda Leganto 1 mg/24 h o 3 mg/24 h.
English: syncope, syncope vasovagal, loss of consciousness), dyskinesia e,
Spanish: (incluyendo síncope, síncope vasovagal, pérdida de la consciencia), disquinesiae, mareo postural e,
English: Tell your doctor or pharmacist if you notice any side effects.
Spanish: Informe a su médico o farmacéutico si nota cualquier efecto adverso.
English: • 3 mg/24 h: Each patch releases 3 mg of rotigotine per 24 hours.
Spanish: • 3 mg/24 h: Un parche libera 3 mg de rotigotina cada 24 horas.
English: Syncope
Spanish: Síncopes
English: At the end of the maintenance treatment an improvement of at least 30% was seen in 60% of the subjects receiving rotigotine, 67% of the subjects receiving pramipexole and 35% of the subjects receiving placebo (Difference rotigotine versus placebo 25%, CI95% 13%; 36%, difference pramipexole versus placebo 32%, CI95% 21%; 43%, difference pramipexole versus rotigotine 7%, CI95% -2%; 17%).
Spanish: Al terminar el tratamiento de mantenimiento se observó una mejoría al menos del 30% en el 60% de los casos tratados con rotigotina, el 67% de los sujetos tratados con pramipexol y el 35% de los tratados con placebo (Diferencia de rotigotina frente a placebo: 25%, IC95% 13%; 36%, diferencia de pramipexol frente a placebo 32%, IC95% 21%; 43%, diferencia de pramipexol frente a rotigotina: 7%, ICI95% -2%; 17%).
English: • 6 mg/24 h: Each patch releases 6 mg of rotigotine per 24 hours.
Spanish: • 6 mg/24 h: Un parche libera 6 mg de rotigotina cada 24 horas.
English: The patients were titrated to their optimal doses of rotigotine or placebo in weekly increments of 2 mg/24 h starting at 4 mg/24 h. Patients in each treatment group were maintained at their optimal dose for 6 months.
Spanish: Los pacientes ajustaron su dosis óptima de rotigotina o placebo con incrementos semanales de 2 mg/24 h a partir de 4 mg/24 h. Los pacientes de cada grupo de tratamiento se mantuvieron con la dosis óptima durante 6 meses.
English: • From the second week, your daily dose may be increased by 1 mg each week - until you get to the right maintenance dose for you.
Spanish: • Desde la segunda semana, la dosis diaria se aumentará en 1 mg semanalmente - hasta alcanzar la dosis de mantenimiento apropiada para usted.
English: SACHET LABEL - WEEK 4
Spanish: ETIQUETA DEL SOBRE - SEMANA 4
English: • The maximum dose is 8 mg each day.
Spanish: • La dosis máxima es de 8 mg al día.
English: syncope, syncope vasovagal, loss of consciousness), dyskinesia, dizziness postural, lethargy
Spanish: (incluyendo síncope, síncope vasovagal, pérdida de consciencia), discinesia, mareos posturales, letargo
English: Each patch of 20 cm contains 9.0 mg of rotigotine.
Spanish: Cada parche de 20 cm contiene 9,0 mg de rotigotina.
English: Patients in each treatment group were maintained for 6 months.
Spanish: En ambos grupos de pacientes, la dosis óptima se mantuvo durante 6 meses.
English: Each patch of 40 cm contains 18.0 mg of rotigotine.
Spanish: Cada parche de 40 cm contiene 18,0 mg de rotigotina.
English: Each patch of 5 cm contains 2.25 mg of rotigotine.
Spanish: Cada parche de 5 cm contiene 2,25 mg de rotigotina.
English: SACHET LABEL - WEEK 2
Spanish: ETIQUETA DEL SOBRE - SEMANA 2
English: Leganto 1 mg/24 h transdermal patch Leganto 3 mg/24 h transdermal patch
Spanish: Leganto 1 mg/24 h parche transdérmico Leganto 3 mg/24 h parche transdérmico
English: Transdermal use
Spanish: Vía transdérmica
English: BOX OF 7 PATCHES - WEEK 1
Spanish: CAJA DE 7 PARCHES - SEMANA 1
English: SACHET LABEL - WEEK 3
Spanish: ETIQUETA DEL SOBRE - SEMANA 3
English: Common: may affect up to 1 in 10 people
Spanish: Frecuentes: pueden afectar hasta 1 de cada 10 pacientes
English: Leganto may decrease blood pressure when you stand up
Spanish: Leganto puede disminuir la presión arterial al levantarse - este efecto podría empeorar al tomar medicamentos para disminuir la presión arterial.
English: • Keep it pressed for about
Spanish: • Mantenga presionando el parche unos 30
English: Tell your doctor if you notice any changes in behaviour, thinking or both, that are listed below.
Spanish: Cambios en el comportamiento y pensamientos anormales Informe a su médico si nota cualquier cambio en el comportamiento, pensamiento o en ambos, de los indicados más abajo.
English: Leganto 8 mg/24 h transdermal patch Each patch releases 8 mg of rotigotine per 24 hours.
Spanish: Leganto 8 mg/24 h parche transdérmico Un parche libera 8 mg de rotigotina cada 24 horas.
English: Vomiting, dyspepsia
Spanish: Náuseas, vómitos
English: • feeling sleepy or dizzy
Spanish: • somnolencia o mareos
English: The outside is tan-coloured and is imprinted with Leganto 4 mg/24 h Leganto 6 mg/24 h or Leganto 8 mg/24 h.
Spanish: La parte exterior es de color tostado y lleva impresa la leyenda Leganto 4 mg/24 h, Leganto 6 mg/24 h o Leganto 8 mg/24 h.
English: The patients were titrated to their optimal dose of rotigotine in weekly increments of 2 mg/24 h starting at 2 mg/24 h to a maximum dose of 8 mg/24 h over 4 weeks.
Spanish: Se ajustó en cada paciente la dosis óptima de rotigotina, iniciando el tratamiento con una dosis de 2 mg/24 h, e incrementándola semanalmente en 2 mg/24 h, hasta un máximo de 8 mg/24 h a lo largo de 4 semanas.
English: Each patch of 10 cm contains 4.5 mg of rotigotine.
Spanish: Cada parche de 10 cm contiene 4,5 mg de rotigotina.
English: 7 transdermal patches of Leganto 8 mg/24 h
Spanish: 7 parches transdérmicos de Leganto 8 mg/24 h
English: erythema, pruritus, irritation, rash, dermatitis, vesicles, pain, eczema, inflammation, swelling, discolouration, papules, exfoliation, urticaria, hypersensitivity)
Spanish: (incluyendo eritema, prurito, irritación, rash, dermatitis, vesículas, dolor, ezcema, inflamación, hinchazón, decoloración, pápulas, excoriaciones, urticaria, hipersensibilidad)
English: AST, ALT, GGT), weight increased, heart rate increased, CPK increasedd
Spanish: (incluyendo AST, ALT, GGT), aumento de pesoe, aumento de la frecuencia cardíacae, aumento CPKd,e
English: BOX OF 7 PATCHES - WEEK 3
Spanish: CAJA DE 7 PARCHES - SEMANA 3
English: 7 transdermal patches of Leganto 6 mg/24 h
Spanish: 7 parches transdérmicos de Leganto 6 mg/24 h
English: BOX OF 7 PATCHES - WEEK 2
Spanish: CAJA DE 7 PARCHES - SEMANA 2
English: BOX OF 7 PATCHES - WEEK 4
Spanish: CAJA DE 7 PARCHES - SEMANA 4
English: The outside of the backing layer is tan-coloured and imprinted with ‘Leganto 2 mg/24 h, 4 mg/24 h, 6 mg/24 h or 8 mg/24 h'.
Spanish: La parte exterior de la capa cobertora es de color tostado y lleva impresa la leyenda ‘Leganto 2 mg/24 h, 4 mg/24 h, 6 mg/24 h u 8 mg/24 h'.
English: Each patch releases 8 mg of rotigotine per 24 hours.
Spanish: Un parche libera 8 mg de rotigotina cada 24 horas.
English: • constipation, dry mouth, heartburn
Spanish: • estreñimiento, sequedad de boca, ardor de estómago
English: Each patch releases 1 mg of rotigotine per 24 hours.
Spanish: Un parche libera 1 mg de rotigotina cada 24 horas.
English: • Each patch releases 2 mg of rotigotine per 24 hours.
Spanish: • Un parche libera 2 mg de rotigotina cada 24 horas.
English: • Your starting dose will be one 1 mg/24 h patch each day.
Spanish: • Su dosis de inicio del tratamiento será un parche de 1 mg/24 h al día.
English: erythema, pruritus, irritation, rash, dermatitis, vesicles, pain, eczema, inflammation, swelling, discolouration, papules, exfoliation, urticaria, hypersensitivity), asthenic conditions a
Spanish: (incluyendo eritema, prurito, irritación, erupción, dermatitis, vesículas, dolor, eczema, inflamación, hinchazón, decoloración, pápulas, excoriaciones, urticaria, hipersensibilid ad), problemas de astenia a
English: 7 transdermal patches of Leganto 4 mg/24 h
Spanish: 7 parches transdérmicos de Leganto 4 mg/24 h
English: Leganto 8 mg/24 h transdermal patch EU/1/11/695/046
Spanish: Leganto 8 mg/24 h parche transdérmico EU/1/11/695/046
English: Transdermal patch
Spanish: Capa cobertora
English: • Your starting daily dose will be one 4 mg/24 h patch each day.
Spanish: • Su dosis de inicio del tratamiento será un parche de 4 mg/24 h al día.
English: The outside is tan-coloured and is imprinted with Leganto 2 mg/24 h, 4 mg/24 h, 6 mg/24 h or 8 mg/24 h.
Spanish: La parte exterior es de color tostado y lleva impresa la leyenda Leganto 2 mg/24 h, 4 mg/24 h, 6 mg/24 h u 8 mg/24 h.
English: • Your starting daily dose will be one 2 mg/24 h patch each day.
Spanish: • Su dosis de inicio del tratamiento será un parche de 2 mg/24 h al día.
English: Leganto 6 mg/24 h transdermal patch Each patch releases 6 mg of rotigotine per 24 hours.
Spanish: Leganto 6 mg/24 h parche transdérmico Un parche libera 6 mg de rotigotina cada 24 horas.
English: Each patch releases 6 mg of rotigotine per 24 hours.
Spanish: Un parche libera 6 mg de rotigotina cada 24 horas.
English: The outside is tan-coloured and is imprinted with Leganto 2 mg/24 h.
Spanish: La parte exterior es de color tostado y lleva impresa la leyenda Leganto 2 mg/24 h.
English: Then, the patch is fold back and the second part of the release liner is removed.
Spanish: A continuación, se dobla el parche y se retira la segunda parte de la cubierta desechable, evitando tocar el lado adherente del parche.
English: Leganto 1 mg/24 h transdermal patch EU/1/11/695/001
Spanish: Leganto 1 mg/24 h parche transdérmico EU/1/11/695/001
English: The patients were titrated to their optimal dose of rotigotine or placebo in weekly increments of 2 mg/24 h starting at 2 mg/24 h to a maximum dose of 6 mg/24 h. Patients in each treatment group were maintained at their optimal dose for 6 months.
Spanish: Se ajustó en cada paciente la dosis óptima de rotigotina o placebo, iniciando el tratamiento con una dosis de 2 mg/24 h, e incrementándola semanalmente en 2 mg/24 h, hasta un máximo de 6 mg/24 h. La dosis óptima de cada paciente se mantuvo durante 6 meses.
English: - If you have any further questions, ask your doctor or pharmacist.
Spanish: • Si tiene alguna duda, consulte a su médico o farmacéutico.
English: Investigations
Spanish: Exploraciones Complementarias
English: Leganto 4 mg/24 h transdermal patch Each patch releases 4 mg of rotigotine per 24 hours.
Spanish: Leganto 4 mg/24 h parche transdérmico Un parche libera 4 mg de rotigotina cada 24 horas.
English: The strengths are 1 mg/24 h, 2 mg/24 h, 3 mg/24 h, 4 mg/24 h, 6 mg/24 h and 8 mg/24 h. The patches of 1 mg/24 h and 3 mg/24 h are used for the treatment of Restless Leg Syndrome, while the patches of 4 mg/24 h, 6 mg/24 h and 8 mg/24 h are used for the treatment of Parkinson's disease.
Spanish: mg/24 h y 3 mg/24 h se utilizan en el tratamiento del Síndrome de Piernas Inquietas, mientras que los parches de 4 mg/24 h, 6 mg/24 h y 8 mg/24 h se usan para el tratamiento de la enfermedad de Parkinson.
English: Leganto 6 mg/24 h transdermal patch EU/1/11/695/037
Spanish: Leganto 6 mg/24 h parche transdérmico EU/1/11/695/037
English: EU/1/11/695/001 [7 transdermal patches] EU/1/11/695/003 [28 transdermal patches] EU/1/11/695/004 [30 transdermal patches]
Spanish: EU/1/11/695/001 [7 parches transdérmicos] EU/1/11/695/003 [28 parches transdérmicos] EU/1/11/695/004 [30 parches transdérmicos]
English: EU/1/11/695/007 [84 transdermal patches (3 packs of 28)]
Spanish: EU/1/11/695/007 [84 parches transdérmicos (3 cajas de 28)]
English: If a generalised skin reaction (e.g. allergic rash, including erythematous, macular, papular rash or pruritus) associated with the use of Leganto is observed, Leganto should be discontinued.
Spanish: Se debe interrumpir el tratamiento con Leganto si se observa una reacción cutánea generalizada asociada al uso de este medicamento (p. ej., exantema alérgico de tipo eritematoso, macular o papular o prurito).
English: Leganto 4 mg/24 h transdermal patch Leganto 6 mg/24 h transdermal patch Leganto 8 mg/24 h transdermal patch
Spanish: Leganto 4 mg/24 h parche transdérmico Leganto 6 mg/24 h parche transdérmico Leganto 8 mg/24 h parche transdérmico
English: What Leganto contains
Spanish: Qué es Leganto
English: Leganto is available in different strength patches which release the medicine over 24 hours.The strengths are 1 mg/24 h, 2 mg/24 h and 3 mg/24 h for the treatment of Restless Leg Syndrome.
Spanish: Las dosis son 1 mg/24 h, 2 mg/24 h y 3 mg/24 h para el tratamiento del Síndrome de Piernas Inquietas.
English: The outside of the backing layer is tan-coloured and imprinted with ‘Leganto 1 mg/24 h'.
Spanish: La parte exterior de la capa cobertora es de color tostado y lleva impresa la leyenda ‘Leganto 1 mg/24 h'.
English: • feeling sick (nausea), vomiting
Spanish: • náuseas, vómitos
English: Leganto 3 mg/24 h transdermal patch EU/1/11/695/019
Spanish: Leganto 3 mg/24 h parche transdérmico EU/1/11/695/019
English: The outside of the backing layer is tan-coloured and imprinted with ‘Leganto 3 mg/24 h'.
Spanish: La parte exterior de la capa cobertora es de color tostado y lleva impresa la leyenda ‘Leganto 3 mg/24 h'.
English: EU/1/11/695/046 [7 transdermal patches] EU/1/11/695/048 [28 transdermal patches] EU/1/11/695/049 [30 transdermal patches]
Spanish: EU/1/11/695/046 [7 parches transdérmicos] EU/1/11/695/048 [28 parches transdérmicos] EU/1/11/695/049 [30 parches transdérmicos]
English: Transdermal patch.
Spanish: Parche transdérmico.
English: EU/1/11/695/019 [7 transdermal patches] EU/1/11/695/021 [28 transdermal patches] EU/1/11/695/022 [30 transdermal patches]
Spanish: EU/1/11/695/019 [7 parches transdérmicos] EU/1/11/695/021 [28 parches transdérmicos] EU/1/11/695/022 [30 parches transdérmicos]
English: At the beginning of therapy dopaminergic adverse reactions such as nausea and vomiting may occur.
Spanish: Al inicio del tratamiento pueden presentarse reacciones adversas dopaminérgicas como náuseas y vómitos, que suelen ser de intensidad leve o moderada incluso si continúa el tratamiento.
English: Leganto 8 mg/24 h transdermal patch rotigotine
Spanish: Leganto 8 mg/24 h parche transdérmico rotigotina
English: Each patch releases 3 mg of rotigotine per 24 hours.
Spanish: Un parche libera 3 mg de rotigotina cada 24 horas.
English: erythema, pruritus, irritation, rash, dermatitis, vesicles, pain, eczema, inflammation,
Spanish: (incluyendo eritema, prurito, irritación, rash, dermatitis, vesículas, dolor, ezcema, inflamación, hinchazón, decoloración, pápulas, excoriaciones, urticaria,
English: EU/1/11/695/037 [7 transdermal patches] EU/1/11/695/039 [28 transdermal patches] EU/1/11/695/040 [30 transdermal patches]
Spanish: EU/1/11/695/037 [7 parches transdérmicos] EU/1/11/695/039 [28 parches transdérmicos] EU/1/11/695/040 [30 parches transdérmicos]
English: Leganto 2 mg/24 h transdermal patch
Spanish: Leganto 2 mg/24 h parche transdérmico
English: Leganto 4 mg/24 h transdermal patch EU/1/11/695/028
Spanish: Leganto 4 mg/24 h parche transdérmico EU/1/11/695/028
English: Each patch releases 4 mg of rotigotine per 24 hours.
Spanish: Un parche libera 4 mg de rotigotina cada 24 horas.
English: Leganto 1 mg/24 h transdermal patch rotigotine
Spanish: Leganto 1 mg/24 h parche transdérmico rotigotina
English: EU/1/11/695/016 [84 transdermal patches (3 packs of 28)]
Spanish: EU/1/11/695/016 [84 parches transdérmicos (3 cajas de 28)]
English: The outside of the backing layer is tan-coloured and imprinted with ‘Leganto 2 mg/24 h'.
Spanish: La parte exterior de la capa cobertora es de color tostado y lleva impresa la leyenda ‘Leganto 2 mg/24 h'.
English: Each patch releases 2 mg of rotigotine per 24 hours.
Spanish: Un parche libera 2 mg de rotigotina cada 24 horas.
English: • Stick the Leganto patch onto your skin as soon as you have opened the sachet and removed the release liner.
Spanish: • Doble el parche por la mitad hasta que se abra la línea en S de la capa desechable.
English: Tell your doctor, pharmacist or nurse if you notice any of the side effects listed above.
Spanish: Informe a su médico, farmacéutico o enfermero si experimenta cualquiera de estos efectos adversos.
English: EU/1/11/695/028 [7 transdermal patches] EU/1/11/695/030 [28 transdermal patches] EU/1/11/695/031 [30 transdermal patches]
Spanish: EU/1/11/695/028 [7 parches transdérmicos] EU/1/11/695/030 [28 parches transdérmicos] EU/1/11/695/031 [30 parches transdérmicos]
English: A single daily dose should be initiated at 4 mg/24 h and then increased in weekly increments of 2 mg/24 h to an effective dose up to a maximum dose of 16 mg/24 h.
Spanish: Posología en pacientes con enfermedad de Parkinson avanzada con fluctuaciones: La administración debe comenzar con una dosis única diaria de 4 mg/24 h y después aumentarse en incrementos semanales de 2 mg/24 h hasta una dosis efectiva no superior a la dosis máxima de 16 mg/24 h.
English: These are usually mild or moderate in intensity and transient even if treatment is continued.
Spanish: Al inicio del tratamiento pueden presentarse reacciones adversas dopaminérgicas como náuseas y vómitos, que suelen ser leves o moderadas y transitorias aunque continúe el tratamiento.
English: EU/1/11/695/010 [7 transdermal patches] EU/1/11/695/012 [28 transdermal patches] EU/1/11/695/013 [30 transdermal patches]
Spanish: EU/1/11/695/010 [7 parches transdérmicos] EU/1/11/695/012 [28 parches transdérmicos] EU/1/11/695/013 [30 parches transdérmicos]
English: EU/1/11/695/043 [84 transdermal patches (3 packs of 28)]
Spanish: EU/1/11/695/043 [84 parches transdérmicos (3 cajas de 28)]
English: EU/1/11/695/025 [84 transdermal patches (3 packs of 28)]
Spanish: EU/1/11/695/025 [84 parches transdérmicos (3 cajas de 28)]
English: EU/1/11/695/052 [84 transdermal patches (3 packs of 28)]
Spanish: EU/1/11/695/052 [84 parches transdérmicos (3 cajas de 28)]
English: - Keep this leaflet.
Spanish: Despegue las láminas.
English: Leganto 6 mg/24 h transdermal patch rotigotine
Spanish: Leganto 6 mg/24 h parche transdérmico rotigotina
English: Leganto 3 mg/24 h transdermal patch rotigotine
Spanish: Leganto 3 mg/24 h parche transdérmico rotigotina
English: Leganto 2 mg/24 h transdermal patch Rotigotine
Spanish: Leganto 2 mg/24 h parche transdérmico rotigotina