FrancophonIA/ELRC3.0 huggingface dataset:
English: only 3 Susceptibility of staphylococci to cephalosporins is inferred from the methicillin susceptibility except for ceftazidme and cefixime and ceftibuten, which do not have breakpoints and should not be used for staphylococcal infections.
Slovenian: 3 Na občutljivost stafilokokov za cefalosporine je mogoče sklepati iz občutljivosti za meticilin, razen za ceftazidim, cefiksim in ceftibuten, ki nimajo mejnih vrednosti in se jih ne sme uporabljati pri stafilokoknih okužbah.
English: To activate, push the plastic needle holder of the Monovial down onto the vial shoulder until a "click" is heard.
Slovenian: Za aktivacijo potisnite plastično držalo igle monoviale dol, proti ovratnemu delu viale, dokler ne zaslišite "klik".
English: Skin and subcutaneous tissue disorders skin rash, urticaria and pruritus erythema multiforme, toxic epidermal necrolysis and StevensJohnson syndrome, angioneurotic oedema
Slovenian: Bolezni kože in podkožja kožni izpuščaj, urtikarija in pruritus multiformni eritem, toksična epidermalna nekroliza in StevensJohnsonov sindrom, angionevrotični edem
English: * Reconstituted solution to be added to 50 or 100 ml of compatible infusion fluid (see information on compatibility, below)
Slovenian: * Pripravljeno raztopino dodamo v 50 ali 100 ml kompatibilne tekočine za infuzijo (glejte podatke o kompatibilnosti spodaj)
English: This diagnosis should be considered in patients with diarrhoea during or subsequent to the administration of cefuroxime (see section 4.8).
Slovenian: Na to diagnozo je treba pomisliti pri vseh bolnikih, ki med uporabo cefuroksima ali po njej dobijo drisko (glejte poglavje 4.8).
English: Discontinuation of therapy with cefuroxime and the administration of specific treatment for Clostridium difficile should be considered.
Slovenian: V poštev pride prenehanje zdravljenja s cefuroksimom in uvedba specifičnega zdravljenja, usmerjenega proti Clostridium difficile.
English: In addition the incidence of adverse reactions associated with cefuroxime sodium may vary according to the indication.
Slovenian: Pojavnost neželenih učinkov, ki so povezani z natrijevim cefuroksimatom, pa se lahko tudi razlikuje glede na indikacijo.
English: Zinacef and associated names (see Annex I) 250 mg powder for solution for injection
Slovenian: Zinacef in povezana imena (glejte Prilogo I) 250 mg prašek za raztopino za injiciranje
English: 5 Breakpoints apply to daily intravenous dose of 750 mg × 3 and a high dose of at least 1.5 g × 3.
Slovenian: 5 Mejne vrednosti veljajo za dnevni intravenski odmerek 750 mg x 3 in visok odmerek vsaj 1,5 g x 3.
English: As with all such antibiotics, in patients with markedly impaired renal function (i.e. C1cr <20 mL/minute) it is recommended that the dosage of cefuroxime should be reduced to compensate for its slower excretion (see section 4.2).
Slovenian: Tako kot velja za vse takšne antibiotike, je bolnikom z izrazito okvarjenim delovanjem ledvic (tj. z očistkom kreatinina < 20 ml/min) odmerek cefuroksima priporočljivo zmanjšati, da bi kompenzirali njegovo počasnejše izločanje (glejte poglavje 4.2).
English: Because elderly patients are more likely to have decreased renal function, care should be taken in cefuroxime dose selection, and it may be useful to monitor renal function (see section 4.2).
Slovenian: Ker je verjetnost zmanjšanega delovanja ledvic pri starejših bolnikih večja, je treba odmerek cefuroksima določiti previdno, koristno pa je tudi spremljati delovanje ledvic (glejte poglavje 4.2).
English: You must not be given Zinacef:
Slovenian: Zdravila Zinacef ne smete prejeti:
English: • if you have ever had a severe allergic (hypersensitive) reaction to any other type of betalactam antibiotic (penicillins, monobactams and carbapenems).
Slovenian: • če ste kdaj imeli hudo alergijsko (preobčutljivostno) reakcijo na kateri koli drugo skupino betalaktamskih antibiotikov (na peniciline, monobaktame ali karbapeneme).
English: Organisms that have acquired resistance to other injectable cephalosporins are expected to be resistant to cefuroxime.
Slovenian: Pričakovati je, da so organizmi, ki so razvili odpornost proti drugim cefalosporinom za injiciranje, odporni proti cefuroksimu.
English: Non-species related breakpoints1
Slovenian: Mejne vrednosti, nepovezane z vrsto1
English: Therefore, as with all such antibiotics, in patients with markedly impaired renal function it is recommended that the dosage of Zinacef should be reduced to compensate for its slower excretion.
Slovenian: Zato je (tako kot velja za vse takšne antibiotike) bolnikom z izrazito okvaro delovanja ledvic odmerek zdravila Zinacef priporočljivo zmanjšati, da bi kompenzirali njegovo počasnejše izločanje.
English: Renal and urinary disorders elevations in serum creatinine, elevations in blood urea nitrogen and decreased creatinine clearance (see section 4.4)
Slovenian: Bolezni sečil povečane vrednosti serumskega kreatinina, povečane vrednosti dušika sečnine v krvi ter zmanjšanje očistka kreatinina (glejte poglavje 4.4)
English: Tell your doctor if you get any of these.
Slovenian: Svojemu zdravniku povejte, če imate kakšno od teh težav.
English: Blood and lymphatic system disorders neutropenia, eosinophilia, decreased haemoglobin concentration leukopenia, positive Coomb's test thrombocytopenia, haemolytic anaemia
Slovenian: Bolezni krvi in limfatičnega sistema nevtropenija, eozinofilija, znižana koncentracija hemoglobina levkopenija, pozitiven Coombsov test trombocitopenija, hemolitična anemija
English: There are no data on the effects of cefuroxime sodium on fertility in humans.
Slovenian: Podatkov o vplivu natrijevega cefuroksimata na plodnost pri človeku ni.
English: No studies on the effects of cefuroxime on the ability to drive and use machines have been performed.
Slovenian: Študije o vplivu na sposobnost vožnje in upravljanja s stroji niso bile izvedene.
English: Cefuroxime sodium is compatible with the following infusion fluids.
Slovenian: Natrijev cefuroksimat je kompatibilen z naslednjimi raztopinami za infundiranje.
English: Tell your doctor before you start on Zinacef if you think that this applies to you.
Slovenian: Preden začnete prejemati zdravilo Zinacef, morate svojemu zdravniku povedati, če mislite, da karkoli od naštetega velja za vas.
English: Cefuroxime is usually active against the following microorganisms in vitro.
Slovenian: Cefuroksim in vitro po navadi deluje proti naslednjim mikroorganizmom: Pogosto občutljivi sevi
English: Important information about excipients
Slovenian: Pomembni podatki o pomožnih snoveh
English: Tell your doctor if this applies to you.
Slovenian: Svojemu zdravniku morate povedati, če to velja za vas.
English: AUC and Cmax appear to increase linearly with increase in dose over the single dose range of 250 to 1000 mg following IM and IV administration.
Slovenian: Kot kaže, se AUC in Cmax povečujeta linearno s povečevanjem odmerka v razponu posamičnega odmerka od 250 do 1000 mg tako po intramuskularni kot po intravenski uporabi.
English: What Zinacef looks like and contents of the pack
Slovenian: Izgled zdravila Zinacef in vsebina pakiranja
English: In vitro the activities of cefuroxime sodium and aminoglycoside antibiotics in combination have been shown to be at least additive with occasional evidence of synergy.
Slovenian: In vitro je bilo dokazano, da natrijev cefuroksimat v kombinaciji z aminoglikozidnimi antibiotiki deluje vsaj aditivno, občasno pa so pri delovanju opazili tudi sinergizem.
English: Surgical prophylaxis for cardiovascular and oesophageal operations
Slovenian: kirurška profilaksa pri kardiovaskularnih operacijah in operacijah požiralnika
English: • red blood cells destroyed too quickly (haemolytic anaemia).
Slovenian: • prehitro propadanje rdečih krvnih celic (hemolitična anemija);
English: Cefuroxime is excreted by glomerular filtration and tubular secretion.
Slovenian: Cefuroksim se izloča z glomerulno filtracijo in tubulno sekrecijo.
English: Cefuroxime
Slovenian: cefuroksim
English: Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs).
Slovenian: Cefuroksim zavira sintezo bakterijske celične stene z vezavo na beljakovine, ki vežejo peniciline (PBP - penicillin binding proteins).
English: The average renal clearance ranges from 114 to 170 mL/min/1.73 m2 following IM or IV administration over the dosage range of 250 to 1000 mg.
Slovenian: Povprečen ledvični očistek sega od 114 do 170 ml/min/1,73 m2 po intramuskularni ali intravenski uporabi odmerkov v razponu od 250 do 1000 mg.
English: Insert the needle of the Monovial into the additive port of the infusion bag.
Slovenian: Vstavite iglo monoviale skozi nastavek za dodatke na infuzijski vrečki.
English: 1.5 g with induction of anaesthesia followed by 750 mg (intramuscularly) every 8 hours for a further 24 hours.
Slovenian: 1,5 g ob indukciji anestezije, nato 750 mg (intramuskularno) na 8 ur nadaljnjih 24 ur.
English: • oral anticoagulants
Slovenian: • peroralni antikoagulanti
English: Peel off the removable top part of the label and remove the cap.
Slovenian: Odlepite odstranljivi zgornji del nalepke in odstranite pokrovček.
English: • outer membrane impermeability, which restricts access of cefuroxime to penicillin binding proteins in Gram-negative bacteria;
Slovenian: • neprepustnosti zunanje membrane, ki omeji dostop cefuroksima do beljakovin, ki vežejo peniciline v po Gramu negativnih bakterijah;
English: Inherently resistant microorganisms Gram-positive aerobes:
Slovenian: Inherentno odporni mikroorganizmi Po Gramu pozitivni aerobi:
English: • inflammation of the colon (large intestine), causing diarrhoea, usually with blood and mucus,
Slovenian: • vnetje kolona (debelega črevesa), ki povzroči drisko, po navadi s krvjo in sluzjo, bolečine v želodcu;
English: You must not be given Zinacef.
Slovenian: Zdravila Zinacef ne smete dobiti.
English: • aminoglycoside-type antibiotics
Slovenian: • aminoglikozidni antibiotiki
English: 5 If you get any side effects Tell your doctor or pharmacist.
Slovenian: Če se vam pojavi kateri koli neželeni učinek Povejte svojemu zdravniku ali farmacevtu.
English: Dose mg
Slovenian: Odmerek mg
English: • decrease in number of blood platelets (cells that help blood to clot - thrombocytopenia)
Slovenian: • zmanjšanje števila krvnih ploščic (celic, ki pomagajo pri strjevanju krvi - trombocitopenija);
English: Determination of blood/plasma glucose levels: Please refer to section 4.4.
Slovenian: Druge interakcije Določanje koncentracije glukoze v krvi/plazmi: glejte poglavje 4.4.
English: Since cefuroxime is primarily eliminated by the kidney, hepatic dysfunction is not expected to have an effect on the pharmacokinetics of cefuroxime.
Slovenian: Ker se cefuroksim izloča predvsem skozi ledvice, ni pričakovati, da bi moteno delovanje jeter vplivalo na njegovo farmakokinetiko.
English: 1.5 g every 8 hours (intravenously or intramuscularly)
Slovenian: 1,5 g na 8 ur (intravensko ali intramuskularno)
English: Serum levels of cefuroxime can be reduced by haemodialysis or peritoneal dialysis.
Slovenian: Serumske vrednosti cefuroksima je mogoče zmanjšati s hemodializo ali peritonealno dializo.
English: Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, Greece, Hungry, Iceland, Ireland, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovenia, Sweden, United Kingdom - Zinacef
Slovenian: Belgija, Bolgarija, Ciper, Češka, Danska, Estonija, Finska, Grčija, Madžarska, Islandija, Irska, Litva, Luksemburg, Malta, Nizozemska, Norveška, Poljska, Portugalska, Romunija, Slovenija, Švedska, Združeno kraljestvo - Zinacef
English: Take special care with Zinacef
Slovenian: Bodite posebno pozorni pri uporabi zdravila Zinacef
English: Adverse reactions at therapeutic doses are not expected, although a risk of diarrhoea and fungus infection of the mucous membranes cannot be excluded.
Slovenian: Pri terapevtskih odmerkih ni pričakovati neželenih učinkov, ni pa mogoče izključiti tveganja za drisko in glivično okužbo sluznic.
English: 750 mg twice daily
Slovenian: 750 mg dvakrat na dan
English: Infants and toddlers > 3 weeks and children < 40 kg
Slovenian: Dojenčki in mali otroci, starejši od 3 tednov, ter otroci s telesno maso < 40 kg
English: • Soft-tissue infections: cellulitis, erysipelas and wound infections.
Slovenian: • okužbe mehkih tkiv: celulitis, erizipel in okužbe ran;
English: Denmark, Finland, Greece, Hungry, Ireland, Lithuania, Malta, Netherlands, Norway, Poland, Sweden, United Kingdom - Zinacef
Slovenian: Danska, Finska, Grčija, Madžarska, Irska, Litva, Malta, Nizozemska, Norveška, Poljska, Švedska, Združeno kraljestvo - Zinacef
English: Concurrent administration of probenecid prolongs the excretion of the antibiotic and produces an elevated peak serum level.
Slovenian: Sočasna uporaba probenecida namreč podaljša izločanje antibiotika in povzroči zvišanje največje koncentracije v serumu.
English: Concurrent treatment with potent diuretics or aminoglycosides
Slovenian: Sočasno zdravljenje z močnimi diuretiki ali aminoglikozidi
English: • changes in your white blood cell count (neutropenia or eosinophilia)
Slovenian: • spremenjeno število belih krvnih celic (nevtropenija ali eozinofilija);
English: After intramuscular (IM) injection of cefuroxime to normal volunteers, the mean peak serum concentrations ranged from 27 to 35 µg/mL for a 750 mg dose and from 33 to 40 µg/mL for a 1000 mg dose, and were achieved within 30 to 60 minutes after administration.
Slovenian: injiciranju cefuroksima zdravim prostovoljcem je povprečna največja koncentracija v serumu segala od 27 do 35 µg/ml z odmerkom 750 mg in od 33 do 40 µg/ml z odmerkom 1000 mg; dosežena je bila v 30 do 60 minutah po uporabi.
English: MARKETING AUTHORISATION NUMBER(S) [To be completed nationally]
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET <[izpolni država članica]>
English: 750 mg every 6 hours (intravenously) 1.5 g every 8 hours (intravenously)
Slovenian: 750 mg na 6 ur (intravensko) 1,5 g na 8 ur (intravensko)
English: • reduced affinity of penicillin-binding proteins for cefuroxime;
Slovenian: • zmanjšane afinitete beljakovin, ki vežejo peniciline, za cefuroksim;
English: The serum half-life after either intramuscular or intravenous injection is approximately 70 minutes.
Slovenian: Serumski razpolovni čas je približno 70 minut tako po intramuskularnem kot intravenskem injiciranju.
English: Recommended doses for Zinacef in renal impairment
Slovenian: Priporočeni odmerki zdravila Zinacef pri okvari ledvic
English: cardiovascular, and gynaecological surgery (including caesarean section).
Slovenian: kardiovaskularnih in ginekoloških operacijah (vključno s carskim rezom).
English: With the vial uppermost, transfer the reconstituted cefuroxime sodium into the infusion bag by squeezing and releasing the bag.
Slovenian: Z zgornjim delom viale prenesite pripravljeni natrijev cefuroksimat v infuzijsko vrečko tako, da vrečko stiskate in spuščate.
English: Gram-negative anaerobes:
Slovenian: Po Gramu negativni anaerobi:
English: Belgium, Bulgaria, Cyprus, Czech Republic, Denmark , Estonia, Finland, Greece, Hungry, Iceland, Ireland, Lithuania, Luxembourg, Netherlands, Norway, Poland, Romania, Slovenia, Sweden, United Kingdom - Zinacef
Slovenian: Belgija, Bolgarija, Ciper, Češka, Danska, Estonija, Finska, Grčija Madžarska, Islandija, Irska, Litva, Luksemburg, Nizozemska, Norveška, Poljska, Romunija, Slovenija, Švedska, Združeno kraljestvoZinacef
English: 6 mL at least 15mL 15 mL*
Slovenian: 6 ml vsaj 15 ml 15 ml*
English: Gram-positive anaerobes:
Slovenian: Po Gramu pozitivni anaerobi:
English: There is an almost complete recovery (85 to 90%) of unchanged cefuroxime in urine within 24 hours of administration.
Slovenian: V 24-ih urah po prejemu odmerka se cefuroksim skoraj v celoti (85-90 %) izloči z urinom v nespremenjeni obliki.
English: PHARMACEUTICAL FORM AND CONTENTS [To be completed nationally]
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA [izpolni država članica]
English: Cefuroxime is effectively removed by haemodialysis and peritoneal dialysis.
Slovenian: Cefuroksim se učinkovito odstrani s hemodializo in peritonealno dializo.
English: 750 mg every 8 hours (intravenously or intramuscularly)
Slovenian: 750 mg na 8 ur (intravensko ali intramuskularno)
English: High-dosage treatments with cephalosporins should be carried out with caution on patients who are taking strong-acting diuretics (such as furosemide) or potential nephrotoxic preparations (such as aminoglycoside antibiotics), since impairment of renal function through such combinations cannot be ruled out.
Slovenian: Potencialno nefrotoksična zdravila in diuretiki zanke Pri bolnikih, ki se zdravijo z močnimi diuretiki, (npr. furosemidom) ali potencialno nefrotoksičnimi učinkovinami (npr. aminoglikozidnimi antibiotiki), je potrebna previdnost pri dajanju visokih odmerkov cefalosporinskih antibiotikov, saj pri tovrstnih kombinacijah ni mogoče izključiti možnosti za okvaro ledvic.
English: • injection site pain, swelling and redness along a vein.
Slovenian: • bolečina na mestu injiciranja, oteklost in pordelost vzdolž vene.
English: Addition volumes and solution concentrations, which may be useful when fractional doses are required.
Slovenian: Dodane količine in koncentracije raztopin, ki so lahko uporabne, če so potrebni frakcijski odmerki.
English: Addition volumes and solution concentrations, which may be useful when fractional doses are required
Slovenian: Dodane količine in koncentracije raztopin, ki so lahko uporabne, če so potrebni frakcijski odmerki
English: It will retain potency for up to 24 hours at room temperature in:
Slovenian: Pri sobni temperaturi se bo njegova učinkovitost ohranila do 24 ur, če ga dodamo:
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity and toxicity to reproduction and development.
Slovenian: Predklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih odmerkih, genotoksičnosti in vpliva na sposobnost razmnoževanja in razvoja ne kažejo posebnega tveganja za človeka.
English: • skin rash, which may blister, and looks like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge) erythema multiformae.
Slovenian: • izpuščaj na koži, ki je lahko mehurjast in na pogled podoben majhnim tarčam (temna osrednja pika, obdana z bledim kolobarjem in temnim obročem ob robu) - multiformni eritem.
English: • diarrhoea, nausea, stomach pain
Slovenian: • driska, slabost v želodcu, bolečina v želodcu.
English: Surgical prophylaxis for gastrointestinal, gynaecological surgery (including caesarean section) and orthopaedic operations
Slovenian: kirurška profilaksa pri operacijah prebavil, ginekoloških (vključno s carskim rezom) in ortopedskih operacijah
English: 1 mL at least 2 mL
Slovenian: 1 ml vsaj 2 ml
English: Adults and adolescents 750 mg to 1.5 g of Zinacef per day divided into two, three or four doses.
Slovenian: Od 750 mg do 1,5 g zdravila Zinacef na dan, razdeljeno na dva, tri ali štiri odmerke.
English: To activate, push the plastic needle holder of the Monovial down onto the vial shoulder until a
Slovenian: Za aktivacijo potisnite plastično držalo igle monoviale navzdol, proti ovratnemu delu viale,
English: • the lungs or chest
Slovenian: • pljuč ali prsnega koša;
English: Cefuroxime has been shown to cross the placenta and attain therapeutic levels in amniotic fluid and cord blood after intramuscular or intravenous dose to the mother.
Slovenian: Dokazano je, da cefuroksim po intramuskularnem ali intravenskem apliciranju materi prehaja skozi placento in v amnijski tekočini ter popkovnični krvi doseže terapevtske koncentracije.
English: History of severe hypersensitivity (e.g. anaphylactic reaction) to any other type of beta-lactam antibacterial agent (penicillins, monobactams and carbapenems).
Slovenian: Anamneza hude preobčutljivosti (npr. anafilaktične reakcije) na katero koli vrsto betalaktamskih protibakterijskih zdravil (peniciline, monobaktame ali karbapeneme).
English: Gram-negative aerobes:
Slovenian: Po Gramu negativni aerobi:
English: Candida overgrowth, overgrowth of Clostridium difficile
Slovenian: Infekcijske in parazitske bolezni razrast kandide, razrast Clostridium difficile
English: Gamma glutamyl transpeptidase activity in rat urine is inhibited by various cephalosporins, however the level of inhibition is less with cefuroxime.
Slovenian: Različni cefalosporini zavirajo aktivnost gama-glutamiltranspeptidaze v podganjem urinu, vendar je izrazitost zavrtja s cefuroksimom manjša.
English: 5% Dextrose Injection BP
Slovenian: 5 % raztopini glukoze za injiciranje (BP);
English: - If you get any side effects, talk to your doctor or nurse.
Slovenian: - Če opazite kateri koli neželeni učinek, se posvetujte s svojim zdravnikom, ali z medicinsko sestro.
English: 1.5 g Monovial powder for solution for infusion Belgium, Luxembourg - Zinacef Italy - Curoxim
Slovenian: 1,5 g prašek za raztopino za infundiranje, monoviala Belgija, Luksemburg - Zinacef Italija - Curoxim
English: • fungal infections
Slovenian: • glivične okužbe;
English: Shake the vial to reconstitute the cefuroxime sodium.
Slovenian: Pretresite vialo, da boste pripravili natrijev cefuroksimat.
English: What Zinacef contains
Slovenian: Kaj vsebuje zdravilo Zinacef
English: • skin rash, which may blister, and looks like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge).
Slovenian: • izpuščaj na koži, ki lahko oblikuje mehurje in daje videz majhnih tarč (temnih osrednjih točk, ki jih obdaja svetlejši predel, obdan s temnim robom).
English: Side effects that may show up in blood tests:
Slovenian: Neželeni učinki, ki se lahko pokažejo pri preiskavah krvi:
English: Cefuroxime is not metabolised.
Slovenian: Cefuroksim se ne presnavlja.
English: You may need extra check-ups to monitor your renal function while you are taking Zinacef.
Slovenian: Morda boste med zdravljenjem z zdravilom Zinacef potrebovali dodatne kontrole za spremljanje delovanja ledvic.
English: Gram-positive aerobes:
Slovenian: Po Gramu pozitivni aerobi:
English: DATE OF REVISION OF THE TEXT [To be completed nationally]
Slovenian: DATUM ZADNJE REVIZIJE BESEDILA {MM/ YYYY} [izpolni država članica]
English: 2 g powder for solution for infusion 2 g intravenous infusion
Slovenian: 2 g prašek za raztopino za infundiranje 2 g intravenska infuzija
English: • Prophylaxis against infection in gastrointestinal (including oesophageal), orthopaedic,
Slovenian: • profilaksa okužb pri operacijah prebavil (vključno z operacijami požiralnika), ortopedskih,
English: Immune system disorders drug fever, interstitial nephritis, anaphylaxis, cutaneous vasculitis
Slovenian: Bolezni imunskega sistema povišana telesna temperatura zaradi zdravljenja z zdravilom (t. i. drug fever), intersticijski nefritis, anafilaksija, kožni vaskulitis
English: However, in older infants (aged >3 weeks) and in children, the serum half-life of 60 to 90 minutes is similar to that observed in adults.
Slovenian: Ugotovljeno je, da je serumski razpolovni čas cefuroksima pri novorojenčkih bistveno podaljšan glede na gestacijsko starost, vendar je pri starejših dojenčkih (starih več kot 3 tedne) in otrocih serumski razpolovni čas podoben kot pri odraslih in znaša od 60 do 90 minut.
English: Preparation of solution for intravenous infusion The contents of the Monovial are added to small volume infusion bags containing 0.9% Sodium Chloride Injection, or 5% Dextrose Injection, or another compatible fluid.
Slovenian: Priprava raztopine za intravensko infundiranje Vsebino monoviale je treba dodati v infuzijske vrečke majhne prostornine, ki vsebujejo 0,9 % raztopino natrijevega klorida za injiciranje, 5 % raztopino glukoze za injiciranje ali drugo kompatibilno tekočino.
English: Zinacef powder for solution for injection and infusion contains sodium.
Slovenian: Zinacef prašek za raztopino za injiciranje in infundiranje vsebuje natrij.