FrancophonIA/ELRC3.0 huggingface dataset:
English: For the initial 3,000 IU (30 mg) bolus, using an enoxaparin sodium graduated pre-filled syringe, expel the excessive volume to retain only 3,000 IU (30 mg) in the syringe.
Danish: Til den initiale 3.000 IE (30 mg) bolus anvendes en gradueret fyldt injektionssprøjte med enoxaparinnatrium, og det overskydende volumen presses ud, så der kun er 3.000 IE (30 mg) tilbage i sprøjten.
English: The 3,000 IU (30 mg) dose can then be directly injected into the intravenous line.
Danish: 3.000 IE (30 mg) dosen kan injiceres direkte i det intravenøse drop.
English: • An initial dose of 3,000 IU (30 mg) of Inhixa will be given as injection into your vein.
Danish: • Du får en startdosis på 3.000 IE (30 mg) Inhixa som en indsprøjtning i en vene.
English: Method of administration Inhixa should not be administered by the intramuscular route.
Danish: Administration Inhixa må ikke administreres intramuskulært.
English: o For patients with a high venous thromboembolism (VTE) risk who undergo abdominal or pelvic surgery for cancer an extended thromboprophylaxis up to 4 weeks is recommended.
Danish: o Hos patienter med høj risiko for venøs tromboemboli (VTE), som får foretaget cancerkirurgi i abdomen eller bækken, anbefales forlænget tromboseprofylakse på op til 4 uger.
English: History of HIT (>100 days)
Danish: HIT i anamnesen (>100 dage)
English: Pack-sizes of 5 vials containing 5 mL.
Danish: Pakningsstørrelser på 5 hætteglas indeholdende 5 ml.
English: These agents include medicinal products such as: - Systemic salicylates, acetylsalicylic acid at anti-inflammatory doses, and NSAIDs including ketorolac, - Other thrombolytics (e.g. alteplase, reteplase, streptokinase, tenecteplase, urokinase) and anticoagulants (see section 4.2).
Danish: Disse lægemidler omfatter: - Systemiske salicylater, acetylsalicylsyre i antiinflammatoriske doser og NSAID'er, herunder ketorolac, - Andre trombolytika (f.eks. alteplase, reteplase, streptokinase, tenecteplase, urokinase) og antikoagulantia (se pkt.
English: All treated medical patients during acute illness Total VTE (%)
Danish: Alle behandlede medicinske patienter under akut sygdom VTE totalt (%)
English: Very rare:
Danish: Meget almindelig:
English: • Inhixa can be added to the tube leaving the body (arterial line) at the start of the dialysis session.
Danish: • Inhixa kan sprøjtes ind i den slange, der udgår fra kroppen (arterieslangen), i begyndelsen af dialysebehandlingen.
English: • Active clinically significant bleeding and conditions with a high risk of haemorrhage, including recent haemorrhagic stroke, gastrointestinal ulcer, presence of malignant neoplasm at high risk of bleeding, recent brain, spinal or ophthalmic surgery, known or suspected oesophageal varices, arteriovenous malformations, vascular aneurysms or major intraspinal or intracerebral vascular abnormalities;
Danish: • Aktiv, klinisk signifikant blødning og tilstande med en høj blødningsrisiko, inklusive nylig hjerneblødning, mavesår ulcus, tilstedeværelse af malignt neoplasme med høj blødningsrisiko, nylig hjerne-, ryg- eller øjenkirurgi, øsofageale varicer eller mistanke herom, arteriovenøse misdannelser, vaskulære aneurismer eller svære intraspinale eller intracerebrale vaskulære abnormiteter.
English: Heparin aPTT Adjusted Intravenous Therapy n (%)
Danish: Intravenøs heparinbehandling justeret i henhold til aPTT n (%)
English: For continuous techniques, a similar delay of 24 hours should be observed before removing the catheter.
Danish: Ved fortsat behandling skal der være et lignende interval på mindst 24 timer, før kateteret fjernes.
English: Prevention of thrombus formation during haemodialysis The recommended dose is 100 IU/kg (1 mg/kg) of enoxaparin sodium.
Danish: Forebyggelse af trombedannelse under hæmodialyse Den anbefalede dosis er 100 IE/kg (1 mg/kg) enoxaparinnatrium.
English: There was a significant treatment benefit of enoxaparin sodium, as compared with unfractionated heparin, in patients who underwent percutaneous coronary intervention within 30 days after randomization (23 percent reduction in relative risk) or who were treated medically (15 percent reduction in relative risk, p=0.27 for interaction).
Danish: Der var en signifikant terapeutisk fordel ved enoxaparinnatrium sammenlignet med ufraktioneret heparin hos patienter, der fik foretaget perkutan koronar intervention inden for 30 dage efter randomisering (reduktion på 23 % af den relative risiko), eller som fik medicinsk behandling (reduktion på 15 % af den relative risiko, p = 0,27 for interaktion).
English: If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
Danish: Hvis du er gravid eller ammer, har mistanke om, at du er gravid, eller planlægger at blive gravid, skal du spørge din læge eller apotekspersonalet til råds, før du bruger dette lægemiddel.
English: Enoxaparin sodium pharmacokinetics appeared similar than control population, after a single 25 IU, 50 IU or 100 IU/kg (0.25, 0.50 or 1.0 mg/kg) intravenous dose however, AUC was two-fold higher than control.
Danish: Enoxaparinnatriums farmakokinetik var sammenlignelig med farmakokinetikken hos kontrolpopulationen efter en enkelt intravenøs dosis på 25 IE, 50 IE eller 100 IE/kg (0,25, 0,50 eller 1,0 mg/kg), dog var AUC to gange større end hos kontrolpopulationen.
English: These include ATIII-dependent inhibition of other coagulation factors like factor VIIa, induction of endogenous Tissue Factor Pathway Inhibitor (TFPI) release as well as a reduced release of von Willebrand factor (vWF) from the vascular endothelium into the blood circulation.
Danish: Disse inkluderer ATIII-afhængig hæmning af andre koagulationsfaktorer som faktor VIIa, induktion af endogen Tissue Factor Pathway Inhibitor (TFPI)-frigivelse og reduceret afgivelse af von Willebrand faktor (vWF) fra det vaskulære endotel til blodcirkulationen.
English: Use in children and adolescents The safety and efficacy of Inhixa has not been evaluated in children or adolescents.
Danish: Brug til børn og unge Sikkerheden og virkningen af Inxixa er ikke undersøgt hos børn og unge.
English: Pack-sizes of 1 vial containing 3 mL.
Danish: Pakningsstørrelser på 1 hætteglas indeholdende 3 ml.
English: • Inhixa is added to the tube leaving the body (arterial line) at the start of the dialysis session.
Danish: • Inhixa sprøjtes ind i den slange, der udgår fra kroppen (arterieslangen), i begyndelsen af dialysebehandlingen.
English: Acetylsalicylic acid is recommended for all patients without contraindications at an initial oral loading dose of 150-300 mg (in acetylsalicylic acid-naive patients) and a maintenance dose of 75-325 mg/day long-term regardless of treatment strategy.
Danish: Det anbefales at give acetylsalicylsyre til alle patienter uden kontraindikationer med en initial oral startdosis på 150-300 mg (hos acetylsalicylsyre-naive patienter) og en langvarig vedligeholdelsesdosis på 75-325 mg/dag uanset behandlingsstrategi.
English: Should the physician decide to administer anticoagulation in the context of epidural or spinal anaesthesia/analgesia or lumbar puncture, frequent monitoring must be exercised to detect any signs and symptoms of neurological impairment such as midline back pain, sensory and motor deficits (numbness or weakness in lower limbs), bowel and/or bladder dysfunction.
Danish: Hvis lægen beslutter at give antikoagulans i forbindelse med epidural eller spinal anæstesi/analgesi eller lumbalpunktur, er regelmæssig monitorering af patienten nødvendig for at opdage ethvert symptom på neurologisk svækkelse såsom rygsmerter langs midtlinjen, sensoriske og motoriske gener (følelsesløshed eller svaghed i underekstremiteterne) og dysfunktion af tarme og/eller urinblære.
English: All Treated DVT Patients with or without PE Total VTE (%)
Danish: Alle behandlede patienter med DVT med eller uden PE VTE totalt (%)
English: Your doctor may request you perform a blood test to check your platelet count.
Danish: Lægen vil tage en blodprøve for at kontrollere antallet af blodplader.
English: To reduce the potential risk of bleeding associated with the concurrent use of enoxaparin sodium and epidural or spinal anaesthesia/analgesia or spinal puncture, consider the pharmacokinetic profile of enoxaparin sodium (see section 5.2).
Danish: For at mindske den potentielle risiko for blødning ved samtidig brug af enoxaparinnatrium og epidural eller spinal anæstesi/analgesi eller spinal punktur skal den farmakokinetiske profil af enoxaparinnatrium tages i betragtning (se pkt.
English: The treatment benefits of enoxaparin sodium, evident for a number of efficacy outcomes, emerged at 48 hours, at which time there was a 35 percent reduction in the relative risk of myocardial re-infarction, as compared with treatment with unfractionated heparin (p < 0.001).
Danish: De terapeutiske fordele ved enoxaparinnatrium, der var evident for et antal effektmål, sås efter 48 timer, hvor den relative risikoreduktion for nyt myokardieinfarkt var 35 % sammenlignet med behandling med ufraktioneret heparin (p < 0,001).
English: The absolute bioavailability of enoxaparin sodium after subcutaneous injection, based on anti-Xa activity, is close to 100%.
Danish: Enoxaparinnatriums absolutte biotilgængelighed efter subkutan injektion er næsten 100 %, baseret på anti-Xa-aktivitet.
English: Extended prophylaxis of DVT following cancer surgery A double-blind, multicentre trial, compared a four-week and a one-week regimen of enoxaparin sodium prophylaxis in terms of safety and efficacy in 332 patients undergoing elective surgery for abdominal or pelvic cancer.
Danish: Et dobbeltblindt multicenterstudie sammenlignede fire ugers behandling og en uges behandling med enoxaparinnatrium-profylakse med hensyn til sikkerhed og virkning hos 332 patienter, der fik foretaget planlagt kirurgi for abdominal- eller bækkencancer.
English: After repeated subcutaneous 150 IU/kg (1.5 mg/kg) once daily dosing, mean AUC of anti-Xa activity is marginally higher at steady state in obese healthy volunteers (BMI 30-48 kg/m2) compared to non-obese control subjects, while maximum plasma anti-Xa activity level is not increased.
Danish: Efter gentagne subkutane doser på 150 IE/kg (1,5 mg/kg) en gang dagligt er den gennemsnitlige AUC af anti-Xa-aktivitet ved steady state marginalt højere hos svært overvægtige, raske forsøgspersoner (BMI 30-48 kg/m2) sammenlignet med ikke-overvægtige kontrolpersoner, mens det maksimale plasmaniveau ikke er øget.
English: 8 hours
Danish: 3 år
English: The needle guard, which is in the form of a plastic cylinder, will be activated automatically and it will completely cover the needle.
Danish: 9) Tryk kanylestemplet kraftigt ind. Nålehætten i form af plast cylinder vil automatisk blive sat på nålen og dække den.
English: Moderate and mild renal impairment
Danish: Moderat og let nedsat nyrefunktion
English: • History of HIT (>100 days)
Danish: • HIT i anamnesen (HIT) (>100 dage)
English: Treatment in patients with unstable angina and non-Qwave MI
Danish: Behandling af patienter med ustabil angina pectoris og MI uden Qtaksudvikling
English: 90 pre-filled syringes
Danish: 90 fyldte sprøjter
English: The risk of these events is higher with the use of post-operative indwelling epidural catheters, with the concomitant use of additional drugs affecting haemostasis such as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), with traumatic or repeated epidural or spinal puncture, or in patients with a history of spinal surgery or spinal deformity.
Danish: Risikoen er øget ved brug af postoperative epidurale katetre, ved samtidig anvendelse af lægemidler, der påvirker hæmostasen såsom non-steroide antiinflammatoriske stoffer (NSAID), med traumatiserende eller gentagen epidural eller spinal punktur og hos patienter med spinal kirurgi eller spinal deformation i anamnesen.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS
Danish: MINDSTEKRAV TIL MÆRKNING PÅ SMÅ INDRE EMBALLAGER FYLDT INJEKTIONSSPRØJTE
English: When given at a dose of 4,000 IU (40 mg) once a day subcutaneously, enoxaparin sodium significantly reduced the incidence of VTE as compared to placebo.
Danish: Ved en dosis på 4.000 IE (40 mg) subkutant en gang dagligt reducerede enoxaparinnatrium signifikant forekomsten af VTE sammenlignet med placebo.
English: After repeated subcutaneous administration of 4,000 IU (40 mg) once daily and 150 IU/kg (1.5 mg/kg) once daily regimens in healthy volunteers, the steady-state is reached on day 2 with an average exposure ratio about 15% higher than after a single dose.
Danish: Efter gentagen subkutan administration af 4.000 IE (40 mg) en gang dagligt og 150 IE/kg (1,5 mg/kg) en gang dagligt til raske forsøgspersoner nås steady state på dag 2 med en gennemsnitlig eksponeringsratio, der er ca. 15 % højere end efter en enkelt dosis.
English: Inhixa 2,000 IU (20 mg)/0.2 mL solution for injection Inhixa 4,000 IU (40 mg)/0.4 mL solution for injection Inhixa 6,000 IU (60 mg)/0.6 mL solution for injection Inhixa 8,000 IU (80 mg)/0.8 mL solution for injection Inhixa 10,000 IU (100 mg)/1 mL solution for injection enoxaparin sodium
Danish: Inhixa 2.000 IE (20 mg)/0,2 ml injektionsvæske, opløsning Inhixa 4.000 IE (40 mg)/0,4 ml injektionsvæske, opløsning Inhixa 6.000 IE (60 mg)/0,6 ml injektionsvæske, opløsning Inhixa 8.000 IE (80 mg)/0,8 ml injektionsvæske, opløsning Inhixa 10.000 IE (100 mg)/1 ml injektionsvæske, opløsning
English: Switch between enoxaparin sodium and direct oral anticoagulants (DOAC) For patients currently receiving enoxaparin sodium, discontinue enoxaparin sodium and start the DOAC 0 to 2 hours before the time that the next scheduled administration of enoxaparin sodium would be due as per DOAC label.
Danish: Skift mellem enoxaparinnatrium og direkte orale antikoagulantia (DOAK) Hos patienter, der får enoxaparinnatrium, seponeres enoxaparinnatrium, og DOAK indledes 0 til 2 timer før det tidspunkt, hvor den næste planlagte administration af enoxaparinnatrium skulle foregå i overensstemmelse med vejledningen for DOAK.
English: However, your doctor may give you a further dose of 50 IU to 100 IU (0.5 to 1 mg) for every kilogram of your weight, if necessary.
Danish: Hvis det er nødvendigt, kan der dog indsprøjtes en dosis mere på 50 IE til 100 IE (0,5-1 mg) pr. kg legemsvægt.
English: At doses used for prophylaxis
Danish: • Ved doser til profylakse
English: For patients with creatinine clearance [15-30] mL/min, consider doubling the timing of puncture/catheter placement or removal to at least 48 hours.
Danish: Hos patienter med kreatininclearance [15-30] ml/min bør det overvejes at fordoble tiden til punktur/anlæggelse eller fjernelse af kateter til mindst 48 timer.
English: Benzyl alcohol Water for injections
Danish: 6.1 Hjælpestoffer Benzylalkohol Vand til injektionsvæsker
English: Placebo once a day subcutaneously n (%)
Danish: Placebo subkutant en gang dagligt n (%)
English: *p value versus placebo = 0.008 #p value versus placebo = 0.537
Danish: *p-værdi versus placebo =0,008 #p-værdi versus placebo =0,537
English: • Hypersensitivity to enoxaparin sodium, heparin or its derivatives, including other low molecular weight heparins (LMWH), to benzyl alcohol or any other of the excipients listed in section 6.1;
Danish: • Overfølsomhed over for enoxaparinnatrium, heparin eller dets derivater, inklusive andre lavmolekylære hepariner (LMWH), benzylalkohol eller et andet af hjælpestofferne anført i pkt.
English: Skin necrosis / cutaneous vasculitis
Danish: Hudnekrose/kutan vasculitis
English: Benzyl alcohol may also cause toxic reactions in infants and children up to 3 years old, due to increased risk of accumulation.
Danish: Benzylalkohol kan også forårsage toksiske reaktioner hos spædbørn og børn op til 3 år på grund af den øget risiko for ophobning.
English: Anti-Xa levels are still detectable at these time points, and these delays are not a guarantee that neuraxial hematoma will be avoided.
Danish: Anti-Xa-niveauer er stadig detekbare på disse tidspunkter, og udsat anlæggelse eller fjernelse af et kateter er ikke garanti for, at der ikke forekommer neuraksialt hæmatom.
English: For patients with a high risk of haemorrhage, the dose should be reduced to 50 IU/kg (0.5 mg/kg) for double vascular access or 75 IU/kg (0.75 mg/kg) for single vascular access.
Danish: Hos patienter med høj risiko for blødning bør dosis reduceres til 50 IE/kg (0,5 mg/kg) ved dobbelt vaskulær adgang eller 75 IE/kg (0,75 mg/kg) ved enkelt vaskulær adgang.
English: A puncture-free interval of at least 12 hours shall be kept between the last injection of enoxaparin sodium at prophylactic doses and the needle or catheter placement.
Danish: Der skal være et punkturfrit interval på mindst 12 timer mellem den sidste injektion af enoxaparinnatrium i profylaktiske doser og anlæggelse af kanyle eller katater.
English: Subcutaneous injection technique
Danish: Subkutan injektionsteknik
English: As with other anticoagulants, haemorrhage may occur in the presence of associated risk factors such as: organic lesions liable to bleed, invasive procedures or the concomitant use of medicinal products affecting haemostasis (see sections 4.4 and 4.5).
Danish: Som med andre antikoagulantia kan der forekomme blødning ved tilstedeværelse af tilknyttede risikofaktorer såsom organiske læsioner, der er tilbøjelige til at bløde, invasive indgreb eller samtidig brug af lægemidler, der påvirker hæmostasen (se pkt.
English: Intravenous (bolus) injection (for acute STEMI indication only) For acute STEMI, treatment is to be initiated with a single intravenous bolus injection immediately followed by a subcutaneous injection.
Danish: Intravenøs (bolus) injektion (kun for indikationen akut STEMI) Ved akut STEMI indledes behandlingen med en enkelt intravenøs bolus injektion umiddelbart efterfulgt af en subkutan injektion.
English: o For patients managed with PCI, if the last subcutaneous dose of enoxaparin sodium was given less than 8 hours before balloon inflation, no additional dosing is needed.
Danish: o Hos patienter, der får foretaget PCI: Hvis den sidste subkutane dosis enoxaparinnatrium blev givet mindre end 8 timer før ballonudvidelsen, er en yderligere dosis ikke nødvendig.
English: Inhixa contains the active substance called enoxaparin sodium that is a low molecular weight heparin (LMWH).
Danish: Inhixa indeholder det aktive stof enoxaparinnatrium, der tilhører en gruppe lægemidler, der kaldes lavmolekylære hepariner.
English: • Hypersensitivity to enoxaparin sodium, heparin or its derivatives, including other low molecular weight heparins (LMWH) or to any of the excipients listed in section 6.1;
Danish: • Overfølsomhed over for enoxaparinnatrium, heparin eller dets derivater, inklusive andre lavmolekylære hepariner (LMWH) eller over for et eller flere af hjælpestofferne anført i pkt.
English: VTE = venous thromboembolic event (DVT and/or PE) *The 95% Confidence Intervals for the treatment differences for total VTE were: - enoxaparin sodium once a day versus heparin (-3.0 to 3.5) - enoxaparin sodium every 12 hours versus heparin (-4.2 to 1.7).
Danish: VTE = venetromboembolisk hændelse (DVT og/eller PE) *95 % konfidensintervaller for behandlingsforskelle for totalt antal VTE var: - enoxaparinnatrium en gang dagligt versus heparin (-3,0 til 3,5) - enoxaparinnatrium hver 12. time versus heparin (-4,2 til 1,7).
English: Enoxaparin sodium should be administered through an intravenous line.
Danish: Enoxaparinnatrium bør administreres i et intravenøst drop.
English: 30 IU/kg (0.3 mg/kg) enoxaparin sodium should be administered.
Danish: 30 IE/kg (0,3 mg/kg) enoxaparinnatrium.
English: Thrombocytopenia and thrombocytosis System organ class
Danish: Trombocytopeni og trombocytose Systemorganklasse
English: To minimize the risk of bleeding following the vascular instrumentation during the treatment of unstable angina, NSTEMI and acute STEMI, adhere precisely to the intervals recommended between enoxaparin sodium injection doses.
Danish: For at minimere risikoen for blødning i forbindelse med vaskulær instrumentering ved behandling af ustabil angina pectoris, NSTEMI og akut STEMI skal de anbefalede intervaller mellem enoxaparinnatrium-injektionerne overholdes nøje.
English: 5) Hold the syringe in the hand you write with (like a pencil) and with your other hand, gently pinch the cleaned area of your abdomen between your forefinger and thumb to make a fold in the skin
Danish: 5) Hold sprøjten i den hånd, du skriver med (ligesom en blyant), og klem forsigtigt sammen om det rensede område af maven og hold hudfolden fast mellem tommel- og pegefingeren med den anden hånd.
English: - At doses used for treatment
Danish: - Ved doser til behandling
English: • Your doctor will decide how much Inhixa to give you.
Danish: • Lægen beslutter, hvor meget Inhixa du skal have.
English: Inhixa should not be administered by the intramuscular route.
Danish: Inhixa må ikke administreres intramuskulært.
English: If the last subcutaneous administration was given more than 8 hours before balloon inflation, an intravenous bolus of 30 IU/kg (0.3 mg/kg) enoxaparin sodium should be administered.
Danish: Hvis den sidste subkutane dosis blev givet mere end 8 timer før ballonudvidelsen, skal der administrere en intravenøs bolusinjektion på 30 IE/kg (0,3 mg/kg) enoxaparinnatrium.
English: • Obese Patients
Danish: • Svært overvægtige patienter
English: Preoperative initiation (2 hours before surgery) of enoxaparin sodium 2,000 IU (20 mg) was proven effective and safe in moderate risk surgery.
Danish: Præoperativ opstart (2 timer før det kirurgiske indgreb) af 2.000 IE (20 mg) enoxaparinnatrium har vist sig at være effektivt og sikkert ved kirurgi med moderat risiko.
English: • If you have any sign of blockage of a blood vessel by a blood clot such as: - cramping pain, redness, warmth, or swelling in one of your legs - these are symptoms of deep vein thrombosis - breathlessness, chest pain, fainting or coughing up blood - these are symptoms of a pulmonary embolism
Danish: • Hvis du får tegn på, at du har fået en blodprop, såsom: - krampelignende smerter, rødme, varmefølelse eller hævelse i det ene ben - dette er symptomer på blodprop i en dybtliggende vene - åndenød, smerter i brystkassen, besvimelse eller ophostning af blod - dette er symptomer på en blodprop i lungerne
English: At doses used for treatment
Danish: Ved doser til behandling
English: In some cases it is not possible to achieve an exact dose due to the graduations on the syringe, and in such case the volume shall be rounded up to the nearest graduation.
Danish: Vær opmærksom på, at det i nogen tilfælde ikke er muligt at opnå en præcis dosis på grund af gradueringen på injektionssprøjten, og i sådanne tilfælde bør volumen rundes op til den nærmeste delestreg.
English: After repeated subcutaneous administration of the 100 IU/kg (1 mg/kg) twice daily regimen, the steady-state is reached from day 3 to 4 with mean exposure about 65% higher than after a single dose and mean maximum and trough anti-Xa activity levels of about 1.2 and 0.52 IU/mL, respectively.
Danish: Efter gentagen subkutan administration af 100 IE/kg (1 mg/kg) to gange dagligt opnås steady state mellem dag 3 og 4 med en gennemsnitlig eksponering, der er ca. 65 % højere end efter en enkelt dosis, og et gennemsnitligt maksimalt og minimalt anti-Xa-niveau på henholdsvis cirka 1,2 og 0,52 IE/ml.
English: In a clinical study of pregnant women with mechanical prosthetic heart valves given enoxaparin sodium (100 IU/kg (1 mg/kg) twice daily) to reduce the risk of thromboembolism, 2 of 8 women developed clots resulting in blockage of the valve and leading to maternal and foetal death.
Danish: I et klinisk studie med gravide kvinder med hjerteklapprotese, der fik enoxaparinnatrium (100 IE/kg (1 mg/kg) to gange dagligt) for at nedsætte risikoen for tromboemboli, opstod der blodpropper hos 2 ud af 8 kvinder.