FrancophonIA/ELRC3.0 huggingface dataset:
English: • if you have high or low levels of vitamin D, calcium or any other minerals
Croatian: • ako imate visoke ili niske razine vitamina D, kalcija ili drugih minerala
English: If you take more Bondronat than you should
Croatian: Ako uzmete više lijeka Bondronat nego što ste trebali
English: • Take your tablet with a full glass of water only (about 200 mL).
Croatian: • Uzmite tabletu lijeka Bondronat samo uz punu čašu vode (oko 200 ml).
English: Contains 88.1 mg lactose (as lactose monohydrate).
Croatian: Sadrži 88,1 mg laktoze (u obliku laktoza hidrata).
English: No data are available (see section 5.1 and section 5.2).
Croatian: Nema dostupnih podataka (vidjeti dijelove 5.1 i 5.2).
English: Take Bondronat at least 6 hours after you last had anything to eat, drink or any other medicines or supplements (e.g. products containing calcium (milk), aluminium, magnesium and iron) except water.
Croatian: Uzmite Bondronat najmanje 6 sati nakon što ste posljednji puta nešto pojeli, popili ili uzeli neki drugi lijek ili nadomjesni pripravak (npr. proizvod koji sadrži kalcij (mlijeko), aluminij, magnezij ili željezo), osim vode.
English: • you have previously been treated with a bisphosphonate (used to treat or prevent bone disorders)
Croatian: • ako ste se prethodno liječili bisfosfonatom (koji se koristi za liječenje ili sprječavanje koštanih poremećaja)
English: Pharmaco-therapeutic group: Medicinal products for treatment of bone diseases, bisphosphonate, ATC Code: M05BA06.
Croatian: Farmakoterapijska skupina: Pripravci za liječenje bolesti kostiju, bisfosfonati, ATK oznaka: M05BA06.
English: • Bondronat is normally given by a doctor or other medical staff who have experience with the treatment of cancer
Croatian: • Bondronat će Vam obično dati liječnik ili drugi zdravstveni radnici koji imaju iskustva u liječenju raka.
English: Milk or antacids should be given to bind Bondronat.
Croatian: Potrebno je uzeti mlijeko ili antacide kako bi se Bondronat vezao.
English: Frequency categories are defined using the following convention: very common (>1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (<1/10,000), not known (cannot be estimated from the available data).
Croatian: Kategorije učestalosti definirane su na sljedeći način: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: • you don't receive routine dental care or have not had a dental check up for a long time
Croatian: • ako nemate osiguranu redovitu stomatološku skrb i već dugo niste bili na kontrolnom stomatološkom pregledu
English: You may be having a serious, potentially life threatening allergic reaction (see section 2)
Croatian: Moguće je da imate alergijsku reakciju koja može biti opasna po život (vidjeti dio 2.)
English: Multiple events were therefore counted only once for the purposes of the analysis.
Croatian: Događaji koji su se ponavljali, za potrebe analize su se stoga brojali samo jedanput.
English: Consideration should be given to the severity of the hypercalcaemia as well as the tumour type.
Croatian: U obzir treba uzeti ozbiljnost hiperkalcijemije i vrstu tumora.
English: However, no dosage adjustment is required when Bondronat is administered with H2-antagonists or medicinal products that increase gastric pH.
Croatian: No nije potrebna prilagodba doze kad se Bondronat primjenjuje s H2-antagonistima ili drugim lijekovima koji povećavaju pH želučane kiseline.
English: Children and adolescents Bondronat should not be used in children and adolescents below the age of 18 years.
Croatian: Djeca i adolescenti Bondronat se ne smije davati djeci i adolescentima mlađima od 18 godina.
English: Bondronat tablets should be taken after an overnight fast (at least 6 hours) and before the first food or drink of the day.
Croatian: Bondronat tablete treba uzimati natašte, nakon noćnog gladovanja (barem 6 sati) i prije uzimanja prvog jutarnjeg obroka ili pića.
English: • stomach problems such as ‘gastroenteritis” or ‘gastritis'
Croatian: • problemi sa želucem kao “gastroenteritis” ili “gastritis”
English: Products containing calcium and other multivalent cations (such as aluminium, magnesium, iron), including milk and food, are likely to interfere with absorption of Bondronat tablets.
Croatian: Proizvodi koji sadrže kalcij i ostale multivalentne katione (kao što su aluminij, magnezij i željezo), uključujući mlijeko i hranu, mogu utjecati na apsorpciju tableta lijeka Bondronat.
English: They are available in packs of 28 and 84 tablets.
Croatian: Tablete su dostupne u pakiranju od 28 tableta i 84 tablete.
English: Medicinal products and supplements (including calcium) should similarly be avoided prior to taking Bondronat tablets.
Croatian: Lijekove i nadomjesne pripravke (uključujući kalcij) također bi trebalo izbjegavati prije uzimanja tableta lijeka Bondronat.
English: White to off-white film-coated tablets, of oblong shape engraved “L2” on one side and “IT” on the other side.
Croatian: Bijele do bjelkaste filmom obložene tablete, ovalnog oblika s utisnutom oznakom "L2" s jedne strane i "IT" s druge strane.
English: Talk to a nurse or a doctor straight away if you notice any of the following serious side effects, you may need urgent medical treatment:
Croatian: Odmah se obratite medicinskoj sestri ili liječniku ako primijetite bilo koju od sljedećih ozbiljnih nuspojava - možda će Vam biti potrebno hitno liječenje:
English: Therefore, Bondronat should not be used during pregnancy.
Croatian: Stoga se Bondronat ne smije koristiti u trudnoći.
English: The highest dose used in clinical trials was 6 mg but this dose does not add any further benefit in terms of efficacy.
Croatian: Najveća doza korištena u kliničkim ispitivanjima iznosila je 6 mg, međutim ova doza nije dovela do daljnjeg poboljšanja učinkovitosti liječenja.
English: Do not chew, suck or crush the tablet.
Croatian: Nemojte žvakati, sisati niti drobiti tabletu.
English: You can drive and use machines as it's expected that Bondronat has no or negligible effect on your ability to drive and use machines.
Croatian: Možete voziti i raditi sa strojevima jer se očekuje da Bondronat ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: • If you have heart problems and the doctor recommended to limit your daily fluid intake
Croatian: • ako imate problema sa srcem i liječnik Vam je preporučio da ograničite dnevni unos tekućine
English: While on treatment, invasive dental procedures should be performed only after careful consideration and be avoided in close proximity to Bondronat administration.
Croatian: Tijekom liječenja, invazivne stomatološke zahvate treba provoditi tek nakon pažljivog razmatranja, a izbjegavati ih u razdoblju blizu vremena primjene lijeka Bondronat.
English: These fractures occur after minimal or no trauma and some patients experience thigh or groin pain, often associated with imaging features of stress fractures, weeks to months before presenting with a completed femoral fracture.
Croatian: Ovi prijelomi nastaju uslijed neznatne traume ili bez traume, dok su neki bolesnici osjećali bol u bedrima ili preponama, koji je često bio povezan sa snimkama stres-fraktura, tjednima, pa čak i mjesecima prije kliničke slike potpunoga prijeloma bedrene kosti.
English: • It helps to prevent other bone problems that may need surgery or radiotherapy Bondronat can also be prescribed if you have a raised calcium level in your blood due to a tumour.
Croatian: • Pomaže spriječiti druge poteškoće s kostima koje bi mogle zahtijevati operaciju ili radioterapiju Bondronat se može propisati i ako imate povišenu razinu kalcija u krvi uzrokovanu tumorom.
English: This medicinal product does not require any special storage conditions prior to reconstitution.
Croatian: Lijek ne zahtijeva posebne uvjete čuvanja prije rekonstitucije.
English: If you are under dental treatment or will undergo dental surgery (e.g. tooth extractions), inform your doctor about your dental treatment and tell your dentist that you are being treated with Bondronat.
Croatian: Ako ste podvrgnuti liječenju zuba ili se morate podvrgnuti stomatološkom kirurškom zahvatu (npr. vađenju zuba), obavijestite svog liječnika o liječenju zuba i recite svom stomatologu da se liječite lijekom Bondronat.
English: • Keep this medicine out of the sight and reach of children
Croatian: • Lijek čuvajte izvan pogleda i dohvata djece.
English: Bondronat tablets contain lactose and should not be administered to patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.
Croatian: Bondronat tablete sadrže laktozu i ne smiju se davati bolesnicima s rijetkim nasljednim poremećajima nepodnošenja galaktoze, deficijencije Lapp laktaze ili malapsorpcije glukoze-galaktoze.
English: **See further information below †Identified in post-marketing experience.
Croatian: ** Vidjeti dodatne informacije niže † Identificirano u razdoblju nakon stavljanja lijeka na tržište.
English: You may be having a serious, potentially life threatening allergic reaction
Croatian: Moguće je da imate alergijsku reakciju koja može biti opasna po život
English: If you stop taking Bondronat
Croatian: Ako prestanete uzimati Bondronat
English: - Hypocalcaemia - Abnormalities of the oesophagus which delay oesophageal emptying such as stricture or achalasia - Inability to stand or sit upright for at least 60 minutes
Croatian: - Nepravilnosti jednjaka koje dovode do zastoja u pražnjenju jednjaka kao što su striktura ili ahalazija - Nemogućnost stajanja ili uspravnog sjedenja barem 60 minuta
English: For these patients and dosages, the median time to achieve normocalcaemia was 4 to 7 days.
Croatian: Za ove bolesnike i doziranje, medijan vremena do postizanja normalne razine kalcija u krvi iznosio je 4 do 7 dana.
English: • you are taking medicines called corticosteroids (such as prednisolone or dexamethasone)
Croatian: • ako uzimate lijekove koji se zovu kortikosteroidi (poput prednizolona ili deksametazona)
English: INFORMATION IN BRAILLE bondronat 50 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU bondronat 50 mg
English: The range of observed apparent half-lives is broad and dependent on dose and assay sensitivity, but the apparent terminal half-life is generally in the range of 10-60 hours.
Croatian: Raspon opaženih prividnih poluživota širok je te ovisi o dozi i osjetljivosti metode, no prividni terminalni poluživot u načelu ima raspon od 10 do 60 sati.
English: Very rare Not known
Croatian: Rijetko Vrlo rijetko Nepoznato
English: Less frequently, a decrease in serum calcium below normal range (hypocalcaemia) is reported.
Croatian: Manje često je prijavljeno sniženje razine kalcija u serumu ispod granice normale (hipokalcijemija).
English: Irritation, inflammation or ulceration of the gullet/food pipe (oesophagus) often with symptoms of severe pain in the chest, severe pain after swallowing food and/or drink, severe nausea, or vomiting may occur, especially if you do not drink a full glass of water and/or if you lie down within an hour of taking Bondronat.
Croatian: Mogu se javiti iritacija, upala ili vrijed jednjaka/cijevi koja povezuje usta sa želucem (ezofagus), često sa simptomima jake boli u prsima, jake boli nakon gutanja hrane i/ili pića, jake mučnine ili povraćanja, osobito ako ne popijete punu čašu vode i/ili ako legnete unutar jednog sata nakon uzimanja lijeka Bondronat.
English: On the basis of the pharmacodynamic and pharmacokinetic profile and reported adverse reactions, it is expected that Bondronat has no or negligible influence on the ability to drive and use machines.
Croatian: S obzirom na farmakodinamički i farmakokinetički profil lijeka i prijavljene nuspojave, očekuje se da Bondronat ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Take your tablet at least 6 hours after you last had anything to eat, drink or any other medicines or supplements except water.
Croatian: Uzmite tabletu najmanje 6 sati nakon što ste posljednji puta nešto pojeli, popili ili uzeli neki drugi lijek ili nadomjesni pripravak, osim vode.
English: Prior to treatment with Bondronat the patient should be adequately rehydrated with 9 mg/ml (0.9%) sodium chloride.
Croatian: Prije liječenja lijekom Bondronat bolesnika treba odgovarajuće rehidrirati s 9 mg/ml (0,9%) otopine natrijevog klorida.
English: • itching or tingling skin around your mouth
Croatian: • svrbež ili trnci oko usta
English: Bioavailability was reduced by approximately 75% when Bondronat tablets were administered 2 hours after a standard meal.
Croatian: Bioraspoloživost se smanjuje za otprilike 75% ako se tablete lijeka Bondronat uzimaju 2 sata nakon standardnog obroka.
English: Total clearance of ibandronic acid is low with average values in the range 84-160 ml/min.
Croatian: Ukupni je klirens ibandronatne kiseline nizak, s prosječnim vrijednostima u rasponu od 84160 ml/min.
English: All Skeletal Related Events (SREs) Placebo n=277
Croatian: Svi događaji vezani uz kosti (SREs) Placebo n=277
English: Your doctor will work out how much Bondronat you will be given depending on your illness.
Croatian: Količinu lijeka Bondronat koju primate odredit će Vaš liječnik ovisno o Vašoj bolesti.
English: Bondronat 50 mg film coated tablets are supplied in blisters (aluminium) containing 7 tablets, which are presented as packs containing 28 or 84 tablets.
Croatian: Bondronat 50 mg filmom obložene tablete su pakirane u blistere (aluminij) sa 7 tableta i dostupne su u pakiranjima od 28 ili 84 tablete.
English: Temporary interruption of Bondronat treatment should be considered until the condition resolves and contributing risk factors are mitigated where possible.
Croatian: Ako je moguće, treba razmotriti privremen prekid liječenja lijekom Bondronat dok se ovo stanje ne povuče i ublaže faktori rizika koji su pridonijeli njegovu razvoju.
English: Bondronat therapy should only be initiated by physicians experienced in the treatment of cancer.
Croatian: Liječenje lijekom Bondronat smiju započeti samo liječnici s iskustvom u liječenju raka.
English: The safety and efficacy of Bondronat in children and adolescents below the age of 18 years have not been established.
Croatian: Sigurnost i djelotvornost lijeka Bondronat u djece i adolescenata mlađih od 18 godina nije ustanovljena.
English: If you have severe kidney problems, your doctor may reduce your dose to one tablet each week.
Croatian: Ako imate tešku bolest bubrega, liječnik Vam može smanjiti dozu na jednu tabletu tjedno.
English: In a study in 130 patients with metastatic breast cancer the safety of Bondronat infused over 1 hour or 15 minutes was compared.
Croatian: U ispitivanju 130 bolesnika s metastatskim rakom dojke uspoređivana je sigurnost primjene lijeka Bondronat infuzijom u trajanju od 1 sata ili 15 minuta.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorsation and any agreed subsequent updates of the RMP.
Croatian: Nositelj odobrenja obavljat će dodatne farmakovigilancijske aktivnosti i intervencije, detaljno objašnjene u dogovorenom Planu upravljanja rizikom, a koji je opisan u Modulu 1.8.2 Odobrenja za stavljanje lijeka u promet, te svim sljedećim dogovorenim nadopunama Plana.
English: Up to now there is no experience of acute poisoning with Bondronat concentrate for solution for infusion.
Croatian: Do sada nije bilo slučajeva akutnog trovanja Bondronat koncentratom za otopinu za infuziju.
English: Clinical studies have not shown any evidence of deterioration in renal function with long term Bondronat therapy.
Croatian: U kliničkim ispitivanjima nije bilo dokaza pogoršanja bubrežne funkcije tijekom dugotrajne terapije lijekom Bondronat.
English: Your doctor may ask you to undergo a dental examination before starting treatment with Bondronat.
Croatian: Vaš liječnik može tražiti da prije početka liječenja lijekom Bondronat obavite stomatološki pregled.
English: For treatment of tumour induced hypercalcaemia, Bondronat concentrate for solution for infusion is generally given as a single infusion.
Croatian: Za liječenje hiperkalcijemije uzrokovane tumorom, Bondronat koncentrat za otopinu za infuziju obično se daje kao jednokratna infuzija.
English: Gender Bioavailability and pharmacokinetics of ibandronic acid are similar in both men and women.
Croatian: Spol Bioraspoloživost i farmakokinetika ibandronatne kiseline su slični u žena i muškaraca.
English: You may have early signs of a possible unusual fracture of the thigh bone
Croatian: To mogu biti rani znakovi mogućeg neuobičajenog prijeloma bedrene kosti.
English: • acetylsalicylic acid and non-steroidal anti-inflammatory medicines called “NSAIDs”, such as ibuprofen or naproxen.
Croatian: • acetilsalicilatnu kiselinu i nesteroidne protuupalne lijekove (NSAR) kao što su ibuprofen i naproksen.
English: • tablet coat: hypromellose, titanium dioxide (E 171), talc, macrogol 6,000
Croatian: • film ovojnica: hipromeloza, titanijev dioksid (E171), talk, makrogol 6000.
English: In clinical pharmacology trial WP18551, after a single dose intravenous administration of 6 mg (15 minutes infusion), mean AUC0-24 increased by 14% and 86%, respectively, in subjects with mild (mean estimated CLcr=68.1 mL/min) and moderate (mean estimated CLcr=41.2 mL/min) renal impairment compared to healthy volunteers (mean estimated CLcr=120 mL/min).
Croatian: U kliničkom farmakološkom ispitivanju WP18551, nakon intravenske primjene jedne doze od 6 mg (15-minutna infuzija) prosječni AUC0-24 se povećao za 14% u ispitanika s blagim (srednja procijenjena vrijednost CLcr = 68,1 ml/min) odnosno za 86% u ispitanika s umjerenim (srednja procijenjena vrijednost CLcr = 41,2 ml/min) oštećenjem bubrega u odnosu na zdrave dobrovoljce (srednja procijenjena vrijednost CLcr = 120 ml/min).
English: Physicians should be alert to any signs or symptoms signaling a possible oesophageal reaction and patients should be instructed to discontinue Bondronat and seek medical attention if they develop dysphagia, odynophagia, retrosternal pain or new or worsening heartburn.
Croatian: Liječnici trebaju biti oprezni prilikom pojave bilo kojeg znaka ili simptoma koji upućuje na moguću reakciju jednjaka, a bolesnici trebaju biti upućeni da prestanu uzimati Bondronat i potraže liječničku pomoć ako se pojavi disfagija, odinofagija, bol iza prsne kosti ili žgaravica ili dođe do pogoršanja žgaravice.
English: This is because NSAIDs, and Bondronat can both irritate your stomach and gut
Croatian: To je važno stoga što i NSAR i Bondronat mogu uzrokovati nadražaj želuca i crijeva
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 25 June 1996
Croatian: Datum prvog odobrenja: 25. lipnja 1996.
English: • heart and circulatory problems (including palpitations, heart attack, hypertension (high blood pressure) and varicose veins)
Croatian: • problemi sa srcem i cirkulacijom (uključujući lupanje srca, srčani udar, povišeni krvni tlak
English: No specific information is available on the treatment of overdosage with Bondronat.
Croatian: Nisu dostupne specifične informacije o liječenju u slučaju predoziranja lijekom Bondronat.
English: It is recommended that the product once diluted be used immediately (see point 5 of this leaflet “How to store Bondronat”).
Croatian: Preporučuje se da se lijek upotrijebi odmah nakon razrjeđivanja (vidjeti dio 5. ove upute o lijeku, “Kako čuvati Bondronat”).
English: Orally administered bisphosphonates may cause local irritation of the upper gastrointestinal mucosa.
Croatian: Peroralno primijenjeni bisfosfonati mogu uzrokovati lokalnu iritaciju sluznice gornjeg dijela gastrointestinalnog sustava.
English: Total clearance of ibandronic acid was reduced to 44 ml/min in the subjects with severe renal impairment compared with 129 mL/min in subjects with normal renal function.
Croatian: Ukupni klirens ibandronatne kiseline bio je smanjen na 44 ml/min u bolesnika s teškim oštećenjima bubrega u usporedbi sa 129 ml/min kod osoba s normalnom funkcijom bubrega.
English: Sodium acetate
Croatian: Natrijev acetat
English: Taking medicines that reduce stomach acid such as cimetidine and ranitidine, may slightly increase the effects of Bondronat.
Croatian: Uzimanje lijekova za smanjenje kiseline u želucu, poput cimetidina i ranitidina, može neznatno povećati učinak lijeka Bondronat.
English: Exposure to ibandronic acid in patients with various degree of renal impairment is related to creatinine clearance (CLcr).
Croatian: Izloženost ibandronatnoj kiselini u bolesnika s različitim stupnjevima oštećenja bubrega povezana je s klirensom kreatinina (CLcr).
English: Also, some other medicines can affect the way Bondronat works.
Croatian: Također, drugi lijekovi mogu utjecati na djelovanje lijeka Bondronat.
English: Rare hereditary problems
Croatian: Rijetki nasljedni poremećaji
English: Paediatric population (see section 4.2 and section 5.1) There are no data on the use of Bondronat in patients less than 18 years old.
Croatian: Pedijatrijska populacija (vidjeti dijelove 4.2 i 5.1) Ne postoje podaci o primjeni lijeka Bondronat u bolesnika mlađih od 18 godina.
English: Bondronat should not be mixed with calcium containing solutions.
Croatian: Bondronat se ne smije miješati s otopinama koje sadrže kalcij.
English: • itching, swelling of your face, lips, tongue and throat, with difficulty breathing.
Croatian: • svrbež, oticanje lica, usana, jezika ili grla, s otežanim disanjem.
English: In the dose range recommended for treatment, the following response rates with the respective confidence intervals have been shown in clinical trials for patients with baseline albumin-corrected serum calcium  3.0 mmol/l after adequate rehydration.
Croatian: U rasponu doza preporučenih za liječenje, sljedeće stope odgovora s pripadajućim intervalima pouzdanosti uočene su u kliničkim ispitivanjima bolesnika s početnom razinom kalcija u serumu korigiranog albuminom od ≥3,0 mmol/l nakon odgovarajuće rehidracije.
English: • Take your tablet as soon as you get up for the day before having your first food, drink, any medicine or supplements
Croatian: • Uzmite tabletu ujutro odmah nakon ustajanja, prije uzimanja prvog jutarnjeg obroka, pića, drugih lijekova ili nadomjesnih pripravaka.
English: Waymade PLC Sovereign House, Miles Gray Road, Basildon, Essex, SS14 3FR United Kingdom
Croatian: Waymade PLC Sovereign House, Miles Gray Road, Basildon, Essex, SS14 3FR
English: If you forget to take Bondronat
Croatian: Ako ste zaboravili uzeti Bondronat
English: MARKETING AUTHORISATION NUMBER(S) EU/1/96/012/009: 28film-coated tablets EU/1/96/012/010: 84 film-coated tablets
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/96/012/009: 28 filmom obloženih tableta EU/1/96/012/010: 84 filmom obložene tablete
English: • pain in your bone or muscles
Croatian: • bol u kostima i mišićima
English: If you experience one of the following symptoms, such as shortness of breath/difficulty breathing, tight feeling in throat, swelling of tongue, dizziness, feeling of loss of consciousness, redness or swelling of face, body rash, nausea and vomiting, you should immediately alert your doctor or nurse (see section 4).
Croatian: Ako se pojavi neki od sljedećih simptoma: nedostatak zraka/otežano disanje, osjećaj stezanja u grlu, oticanje jezika, omaglica, osjećaj da ćete izgubiti svijest, crvenilo ili oticanje lica, osip po tijelu, mučnina i povraćanje, morate na to odmah upozoriti svog liječnika ili medicinsku sestru (vidjeti dio 4).
English: Bondronat contains lactose
Croatian: Bondronat sadrži laktozu.
English: Manufacturer Waymade PLC Sovereign House, Miles Gray Road, Basildon, Essex, SS14 3FR United Kingdom
Croatian: Proizvođač Waymade PLC Sovereign House, Miles Gray Road, Basildon, Essex, SS14 3FR
English: Female patients with breast cancer and radiologically confirmed bone metastases were randomised to receive placebo (158 patients) or 6 mg Bondronat (154 patients).
Croatian: Bolesnice s rakom dojke i radiološki potvrđenim koštanim metastazama randomizirane su za primanje placeba (158 bolesnica) ili 6 mg lijeka Bondronat (154 bolesnica).