FrancophonIA/ELRC3.0 huggingface dataset:
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer packaging for 4 week treatment initiation pack ( 20 mg, 7 tablets, week 4)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Vanjsko pakiranje za 4-tjedno pakiranje za početak liječenja (20 mg, 7 tableta, 4. tjedan)
English: PHARMACEUTICAL FORM AND CONTENTS Treatment initiation pack
Croatian: Pakiranje za početak liječenja
English: Take one 10 mg tablet once a day (white to off-white, capsule shaped, biconvex, with a break score on one side and debossed with “10” on the other side) for 7 days.
Croatian: Uzimajte jednu tabletu od 10 mg jednom dnevno (bijelu do gotovo bijelu, bikonveksnu tabletu u obliku kapsule, s razdjelnom crtom na jednoj strani i s utisnutim “10” na drugoj strani) tijekom 7 dana.
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 10 mg tablets memantine hydrochloride
Croatian: Memantin ratiopharm 10 mg tablete memantinklorid
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer packaging for 4 week treatment initiation pack ( 10 mg, 7 tablets, week 2)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Vanjsko pakiranje za 4-tjedno pakiranje za početak liječenja (10 mg, 7 tableta, 2. tjedan)
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 5 mg memantine hydrochloride equivalent to 4.15 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna filmom obložena tableta sadrži 5 mg memantinklorida, što odgovara 4,15 mg memantina.
English: Each film-coated tablet contains 20 mg memantine hydrochloride equivalent to 16.62 mg memantine.
Croatian: Svaka filmom obložena tableta sadržava 20 mg memantinklorida, što odgovara 16,62 mg memantina.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 15 mg memantine hydrochloride equivalent to 12.46 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna filmom obložena tableta sadrži 15 mg memantinklorida, što odgovara 12,46 mg memantina.
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 20 mg tablets memantine hydrochloride
Croatian: Memantin ratiopharm 20 mg tablete memantinklorid
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer packaging for 4 week treatment initiation pack ( 15 mg, 7 tablets, week 3)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Vanjsko pakiranje za 4-tjedno pakiranje za početak liječenja (15 mg, 7 tableta, 3. tjedan)
English: 100 film-coated tablets
Croatian: 10 mg filmom obložene tablete
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 10 mg film-coated tablets Memantine ratiopharm 20 mg film-coated tablets
Croatian: Memantin ratiopharm 10 mg filmom obložene tablete Memantin ratiopharm 20 mg filmom obložene tablete
English: Each film-coated tablet contains 10 mg of memantine hydrochloride equivalent to 8.31 mg memantine.
Croatian: Jedna filmom obložena tableta sadrži 10 mg memantinklorida, što odgovara 8,31 mg memantina.
English: White to off-white, capsule shaped, biconvex tablets with a break score on one side and debossed with “10” on the other side.
Croatian: Bijele do gotovo bijele, bikonveksne tablete u obliku kapsule s razdjelnom crtom na jednoj strani i utisnutim “10” na drugoj strani.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer packaging for 4 week treatment initiation pack ( 5 mg, 7 tablets, week 1)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Vanjsko pakiranje za 4-tjedno pakiranje za početak liječenja (5 mg, 7 tableta, 1. tjedan)
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 5 mg film-coated tablets memantine hydrochloride
Croatian: Memantin ratiopharm 5 mg filmom obložene tablete memantinklorid
English: Take one 15 mg tablet once a day (white to off-white, capsule shaped, biconvex, plain on one side and debossed with “15” on the other side) for 7 days.
Croatian: Uzimajte jednu tabletu od 15 mg jednom dnevno (bijelu do gotovo bijelu, bikonveksnu tabletu u obliku kapsule, glatku s jedne strane i s utisnutim “15” s druge strane) tijekom 7 dana.
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 20 mg film-coated tablets memantine hydrochloride
Croatian: Memantin ratiopharm 20 mg filmom obložene tablete memantinklorid
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 15 mg film-coated tablets memantine hydrochloride
Croatian: Memantin ratiopharm 15 mg filmom obložene tablete memantinklorid
English: Take one 5 mg tablet once a day (white to off-white, capsule shaped, biconvex, plain on one side and debossed with “5” on the other side) for 7 days.
Croatian: Uzimajte jednu tabletu od 5 mg jednom dnevno (bijelu do gotovo bijelu, bikonveksnu tabletu u obliku kapsule, glatku s jedne strane i s utisnutim “5” s druge strane) tijekom 7 dana.
English: NAME OF THE MEDICINAL PRODUCT Memantine ratiopharm 10 mg film-coated tablets memantine hydrochloride
Croatian: Memantin ratiopharm 10 mg filmom obložene tablete memantinklorid
English: 6.5 Nature and contents of container 10 mg film-coated tablets
Croatian: OBLIK I SADRŽAJ Filmom obložena tableta 100 filmom obloženih tableta
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 20 mg memantine hydrochloride equivalent to 16.62 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna filmom obložena tableta sadrži 20 mg memantinklorida, što odgovara 16,62 mg memantina.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 10 mg memantine hydrochloride equivalent to 8.31 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna filmom obložena tableta sadrži 10 mg memantinklorida, što odgovara 8,31 mg memantina.
English: The patient should take one 5 mg film-coated tablet per day (white to off-white, capsule shaped, biconvex tablets plain on one side and debossed with “5” on the other side) for 7 days.
Croatian: 1. tjedan (1.-7. dan): bolesnik treba uzimati jednu filmom obloženu tabletu od 5 mg (bijele do gotovo bijele, bikonveksne tablete u obliku kapsule, glatke s jedne strane i s utisnutim “5” s druge strane) dnevno tijekom 7 dana.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 20 mg memantine hydrochloride equivalent to 16.62 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna tableta sadrži 20 mg memantinklorida, što odgovara 16,62 mg memantina.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 10 mg memantine hydrochloride equivalent to 8.31 mg memantine.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna tableta sadrži 10 mg memantinklorida, što odgovara 8,31 mg memantina.
English: White to off-white, capsule shaped, biconvex tablets plain on one side and debossed with “5” on the other side.
Croatian: Bijele do gotovo bijele, bikonveksne tablete u obliku kapsule, glatke s jedne strane i s utisnutim “5” s druge strane.
English: White to off-white, capsule shaped, biconvex tablets plain on one side and debossed with “15” on the other side.
Croatian: Bijele do gotovo bijele, bikonveksne tablete u obliku kapsule, glatke s jedne strane i s utisnutim “15” s druge strane.
English: The patient should take one 20 mg film-coated tablet per day (white to off-white, capsule shaped, biconvex tablets with a break score on one side and debossed with “20” on the other side.)
Croatian: 4. tjedan (22.-28. dan): bolesnik treba uzimati jednu filmom obloženu tabletu od 20 mg (bijele do gotovo bijele, bikonveksne tablete u obliku kapsule, s razdjelnom crtom na jednoj strani i utisnutim “20” na drugoj strani) dnevno tijekom 7 dana.
English: Shelf life after first opening: 6 months 6.4 Special precautions for storage Blister packs
Croatian: HDPE bočice: Rok valjanosti nakon prvog otvaranja: 6 mjeseci
English: Pharmaceutical form
Croatian: Jačina Farmaceutski oblik
English: Strength
Croatian: Karencija
English: This is called overgrowth.
Croatian: To se zove prekomjeran rast.
English: The first 2 numbers indicate the month; the next 4 numbers indicate the year.
Croatian: Prva 2 broja označavaju mjesec, a sljedeća 4 broja godinu.
English: The effects of this change are anticipated to be transient.
Croatian: Predviđa se da je učinak ove promjene prolazan.
English: * Activity has been satisfactorily demonstrated in clinical studies.
Croatian: * Aktivnost je zadovoljavajuće dokazana u kliničkim studijama.
English: Infuse over a period of 30 minutes.
Croatian: Primijenite infuzijom tijekom 30 minuta.
English: Your doctor has prescribed INVANZ because you or your child has one (or more) of the following types of infection:
Croatian: Liječnik je propisao INVANZ jer Vi ili Vaše dijete imate jednu (ili više) od sljedećih vrsta infekcija:
English: - Allergies to any medicines, including antibiotics.
Croatian: - alergije na bilo koji lijek, uključujući antibiotike.
English: Therefore, caution should be exercised in such unusual cases.
Croatian: Stoga je u takvim neuobičajenim slučajevima potreban oprez.
English: Repeated evaluation of the patient's condition is essential.
Croatian: Neophodno je ponovno procijeniti stanje bolesnika.
English: The first signs of a severe allergic reaction may include swelling of the face and/or throat.
Croatian: Prvi znakovi ozbiljne alergijske reakcije mogu obuhvaćati oticanje lica i/ili grla.
English: frequency of acquired resistance > 50 % in some Member States.
Croatian: Učestalost stečene rezistencije je >50% u nekim državama članicama.
English: Anaerobes:
Croatian: Anaerobi:
English: Solutions should be used within 4 hours of their removal from the refrigerator.
Croatian: Otopine se moraju primijeniti unutar 4 sata od vađenja iz hladnjaka.
English: Always tell your doctor about all medicines that you are taking or plan to take, including those obtained without a prescription.
Croatian: Uvijek obavijestite svog liječnika o svim lijekovima koje uzimate ili namjeravate uzimati, uključujući i one koje ste nabavili bez recepta.
English: What INVANZ is and what it is used for
Croatian: Što je INVANZ i za što se koristi
English: INVANZ can be given to persons 3 months of age and older.
Croatian: INVANZ mogu primati osobe u dobi od 3 mjeseca i starije.
English: This is because INVANZ can affect the way some other medicines work.
Croatian: To je zato jer INVANZ može utjecati na djelovanje nekih drugih lijekova.
English: Commonly susceptible species:
Croatian: Vrste koje su obično osjetljive:
English: Your doctor will decide whether you should use INVANZ in combination with these other medicines.
Croatian: Liječnik će odlučiti trebate li primati INVANZ u kombinaciji s tim drugim lijekovima.
English: Adequate and well-controlled studies have not been performed in pregnant women.
Croatian: Nisu provedene adekvatne i dobro kontrolirane studije u trudnica.
English: It has the ability to kill a wide range of bacteria (germs) that cause infections in various parts of the body.
Croatian: On može uništiti širok raspon bakterija (klica) koje uzrokuju infekcije u različitim dijelovima tijela.
English: If not used immediately, in use storage times are the responsibility of the user.
Croatian: Ako se ne primijeni odmah, vrijeme čuvanja do primjene odgovornost je korisnika.
English: Common (≥ 1/100 to < 1/10); Uncommon (≥ 1/1,000 to < 1/100); Rare (≥ 1/10,000 to < 1/1,000); Very rare (< 1/10,000); Not known (cannot be estimated from the available data)
Croatian: Često (≥1/100 i <1/10); manje često (≥1/1000 i <1/100); rijetko (≥1/10 000 i <1/1000); vrlo rijetko (<1/10 000); nepoznato (ne može se procijeniti na temelju dostupnih podataka).
English: The overall safety profile is comparable to that in adult patients.
Croatian: Ukupan sigurnosni profil bio je usporediv s onim u odraslih bolesnika.
English: • decreased consciousness
Croatian: • smanjena svijest
English: Date of first authorisation: 18 April 2002 Date of latest renewal: 22 December 2011
Croatian: Datum posljednje obnove odobrenja: 22. prosinca 2011.
English: This is because you may have a condition known as colitis (an inflammation of the bowel).
Croatian: To je stoga što možda imate stanje koje se zove kolitis (upalu debelog crijeva).
English: INVANZ has not been studied in pregnant women.
Croatian: INVANZ nije ispitivan u trudnica.
English: While antibiotics including INVANZ kill certain bacteria, other bacteria and fungi may continue to grow more than normal.
Croatian: Dok antibiotici, uključujući INVANZ, uništavaju određene bakterije, druge bakterije i gljivice mogu nastaviti rasti više nego obično.
English: If an allergic reaction to ertapenem occurs (see section 4.8), discontinue the therapy immediately.
Croatian: Ako nastupi alergijska reakcija na ertapenem (vidjeti dio 4.8), liječenje treba odmah prekinuti.
English: If superinfection occurs during therapy, appropriate measures should be taken.
Croatian: Ako se tijekom liječenja pojavi superinfekcija, treba poduzeti odgovarajuće mjere.
English: Do not drive or use any tools or machines until you know how you react to the medicine.
Croatian: Nemojte voziti niti rukovati alatima ili strojevima dok ne znate kako reagirate na ovaj lijek.
English: It is very important that you continue to receive INVANZ for as long as your doctor prescribes it.
Croatian: Vrlo je važno da nastavite primati INVANZ onoliko dugo koliko Vam je liječnik propisao.
English: Sub-optimal exposure
Croatian: Suboptimalna izloženost
English: Your doctor will decide how many days' treatment you need.
Croatian: Liječnik će odlučiti koliko dana trebate primati lijek.
English: Your doctor will monitor you for overgrowth and treat you if necessary.
Croatian: Liječnik će Vas kontrolirati zbog mogućeg prekomjernog rasta mikroba i liječiti ako bude potrebno.
English: Rare: Allergy
Croatian: Rijetko: alergija
English: Efficacy in Paediatric Studies
Croatian: Djelotvornost u pedijatrijskim studijama
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety, pharmacology, repeated-dose toxicity, genotoxicity and toxicity to reproduction and development.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti, reproduktivne i razvojne toksičnosti.
English: If these symptoms occur tell your doctor straight away as you may need urgent medical treatment.
Croatian: Ako se pojave ti simptomi, odmah obavijestite liječnika jer će Vam možda trebati hitno liječenje.
English: Bacteroides fragilis and species in the B. fragilis Group* Inherently resistant organisms:
Croatian: Bacteroides fragilis i vrste iz skupine B. fragilis* Organizmi s urođenom rezistencijom:
English: Other medicines and INVANZ
Croatian: Drugi lijekovi i INVANZ
English: Package Leaflet: information for the user
Croatian: Uputa o lijeku: Informacije za korisnika
English: Ceftriaxone n/m % n/m %
Croatian: Ceftriakson n/m % n/m %
English: If you miss a dose of INVANZ
Croatian: Ako ste propustili dozu lijeka INVANZ
English: 3 to 23 months 31/35 88.6 13/13 100.0
Croatian: 3 do 23 mjeseca 31/35 88,6 13/13 100,0
English: What you need to know before you are given INVANZ
Croatian: Što morate znati prije nego počnete primati INVANZ
English: Gram-negative aerobes:
Croatian: Gram-negativni aerobi:
English: Microbiological susceptibility
Croatian: Mikrobiološka osjetljivost
English: The usual duration of therapy with INVANZ is 3 to 14 days but may vary depending on the type and severity of infection and causative pathogen(s).
Croatian: Trajanje terapije lijekom INVANZ obično iznosi od 3 do 14 dana, ali može varirati ovisno o vrsti i težini infekcije te njezinu uzročnom patogenu (patogenima).
English: Do not freeze the reconstituted solutions.
Croatian: Ne zamrzavati rekonstituirane otopine.
English: If you are given more INVANZ than you should
Croatian: Ako primite više lijeka INVANZ nego što ste trebali
English: - Central nervous system disorders, such as localised tremors, or seizures.
Croatian: - poremećaje središnjeg živčanog sustava, kao što su lokalizirane drhtavice (tremori) ili napadaji.
English: Overdosing of ertapenem is unlikely.
Croatian: Predoziranje ertapenemom nije vjerojatno.
English: The safety and efficacy of INVANZ in children below 3 months of age have not yet been established.
Croatian: Sigurnost i djelotvornost lijeka INVANZ u djece mlađe od 3 mjeseca nisu još ustanovljene.
English: What INVANZ is and what it is used for What you need to know before you are given INVANZ How to use INVANZ
Croatian: Što je INVANZ i za što se koristi Što morate znati prije nego počnete primati INVANZ Kako primjenjivati INVANZ Moguće nuspojave
English: During treatment, if you experience an allergic reaction (such as swelling of the face, tongue or throat, difficulty in breathing or swallowing, skin rash), tell your doctor straight away as you may need urgent medical treatment.
Croatian: Ako za vrijeme liječenja dobijete alergijsku reakciju (primjerice oticanje lica, jezika ili grla, otežano disanje ili gutanje, osip kože), odmah obavijestite liječnika jer će Vam možda trebati hitno liječenje.
English: Prevention
Croatian: Prevencija
English: Serious anaphylactic reactions require immediate emergency treatment.
Croatian: Ozbiljne anafilaktičke reakcije preosjetljivosti zahtijevaju hitno liječenje.
English: In vitro studies in human liver microsomes indicate that ertapenem does not inhibit metabolism mediated by any of the six major CYP isoforms: 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4.
Croatian: In vitro studije na humanim jetrenim mikrosomima pokazuju da ertapenem ne inhibira metabolizam posredovan bilo kojim od šest glavnih CYP izoformi: 1A2, 2C9, 2C19, 2D6, 2E1 i 3A4.
English: Gram-positive aerobes:
Croatian: Gram-pozitivni aerobi:
English: Information from clinical studies
Croatian: Podaci iz kliničkih studija
English: There are no adequate and well-controlled studies regarding the effect of ertapenem use on fertility in men and women.
Croatian: Nema adekvatnih i dobro kontroliranih studija učinka ertapenema na plodnost muškaraca i žena.
English: Warnings and precautions Talk to your doctor, nurse or pharmacist before taking INVANZ.
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku, medicinskoj sestri ili ljekarniku prije nego primite INVANZ.
English: Medicinal products that inhibit peristalsis should not be given.
Croatian: Ne smiju se davati lijekovi koji inhibiraju peristaltiku.
English: Prolonged use of ertapenem may result in overgrowth of non-susceptible organisms.
Croatian: Dugotrajna primjena ertapenema može dovesti do prekomjernog rasta neosjetljivih mikroorganizama.
English: In Escherichia coli, affinity is strongest to PBPs 2 and 3.
Croatian: Escherichia coli ima najjači afinitet za PBP-2 i PBP-3.
English: Adults 18 years of age and older:
Croatian: Odrasli u dobi od 18 godina i stariji:
English: The prevalence of acquired resistance may vary geographically and with time for selected species and local information on resistance is desirable, particularly when treating severe infections.
Croatian: Prevalencija stečene rezistencije za određene vrste može se razlikovati po zemljopisnim regijama i vremenskim razdobljima te je poželjno imati lokalne podatke o rezistenciji, osobito kod liječenja teških infekcija.
English: If you experience raised or fluid-filled skin spots over a large area of your body, tell your doctor or nurse straight away.
Croatian: Ako Vam se pojave uzdignute ili tekućinom ispunjene mrlje na koži na velikom dijelu tijela, odmah obavijestite svog liječnika ili medicinsku sestru.
English: • abnormal movements
Croatian: • neuobičajeni pokreti
English: Do not store above 25C.
Croatian: Ne čuvati na temperaturi iznad 25°C.
English: • Low blood sugar
Croatian: • niska razina šećera u krvi
English: There is relatively little experience with ertapenem in children less than two years of age.
Croatian: Relativno je malo iskustva s primjenom ertapenema u djece mlađe od dvije godine.
English: Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryo-foetal development, parturition or post-natal development.
Croatian: Ispitivanja na životinjama ne ukazuju na izravne niti neizravne štetne učinke na trudnoću, embriofetalni razvoj, okot i postnatalni razvoj.
English: Ertapenem Ticarcillin/clavulanate n/m % n/m %
Croatian: Tikarcilin/klavulanat n/m % n/m %
English: INVANZ is indicated in paediatric patients (3 months to 17 years of age) and in adults for the treatment of the following infections when caused by bacteria known or very likely to be susceptible to ertapenem and when parenteral therapy is required (see sections 4.4 and 5.1):
Croatian: INVANZ je indiciran u pedijatrijskih bolesnika (u dobi od 3 mjeseca do 17 godina) i u odraslih za liječenje sljedećih infekcija ako su uzrokovane bakterijama koje su sigurno ili vrlo vjerojatno osjetljive na ertapenem i kada je potrebna parenteralna terapija (vidjeti dijelove 4.4 i 5.1):
English: Based on the data available it cannot be excluded that in the few cases of surgical interventions exceeding 4 hours, patients could be exposed to sub-optimal ertapenem concentrations and consequently to a risk of potential treatment failure.
Croatian: Na temelju dostupnih podataka ne može se isključiti da bi u malom broju kirurških zahvata koji traju dulje od 4 sata koncentracije ertapenema kojima su bolesnici izloženi mogle biti manje od optimalnih, s posljedičnim rizikom od mogućeg neuspješnog liječenja.
English: Treatment was discontinued due to adverse reactions in 1.3 % of patients.
Croatian: Liječenje je zbog nuspojava prekinuto u 1,3% bolesnika.
English: Intravenous administration: INVANZ should be infused over a period of 30 minutes.
Croatian: Intravenska primjena: INVANZ treba davati u infuziji tijekom 30 minuta.
English: Preclinical studies do not indicate direct or indirect harmful effects with respect to fertility (see section 5.3).
Croatian: Pretkliničke studije ne ukazuju na izravne niti neizravne štetne učinke na plodnost (vidjeti dio 5.3).
English: • Infection affecting the lungs (pneumonia)
Croatian: • infekciju koja zahvaća pluća (upalu pluća)
English: Long-term studies in animals to evaluate the carcinogenic potential of ertapenem have not been performed.
Croatian: Nisu provedena dugotrajna ispitivanja na životinjama koja bi ispitala kancerogeni potencijal ertapenema.
English: Tell your doctor about any medical condition you have or have had including: - Kidney disease.
Croatian: Obavijestite svog liječnika o svim zdravstvenim tegobama koje imate ili ste imali, uključujući: - bolest bubrega.
English: Do not store above 25C
Croatian: Ne čuvati na temperaturi iznad 25°C
English: Shake well to dissolve.
Croatian: Dobro protresite da se otopi.
English: Pharmacotherapeutic group: Antibacterials for systemic use, carbapenems, ATC code: J01DH03
Croatian: Farmakoterapijska skupina: Lijekovi za liječenje bakterijskih infekcija za sustavnu primjenu, karbapenemi, ATK oznaka: J01DH03
English: What INVANZ contains
Croatian: Što INVANZ sadrži
English: Of the 80 % recovered in urine, approximately 38 % is excreted as unchanged ertapenem and approximately 37 % as the ring-opened metabolite.
Croatian: Od 80% ertapenema pronađenog u mokraći, otprilike 38% izluči se u nepromijenjenom obliku, a 37% kao metabolit otvorenog prstena.
English: Women who are receiving INVANZ should not breast-feed, because it has been found in human milk and the breast-fed baby may therefore be affected.
Croatian: Žene koje primaju INVANZ ne smiju dojiti jer je ovaj lijek pronađen u majčinom mlijeku te stoga može djelovati na dojenče.
English: Experience in the use of ertapenem in the treatment of severe infections is limited.
Croatian: Iskustvo s primjenom ertapenema u liječenju teških infekcija je ograničeno.
English: Supplied in packs of 1 vial or 10 vials.
Croatian: Dostupno u pakiranju od 1 bočice ili 10 bočica.
English: INVANZ is supplied in packs of 1 vial or 10 vials.
Croatian: INVANZ je dostupan u pakiranju od 1 bočice ili 10 bočica.
English: The mechanism of action of ertapenem differs from that of other classes of antibiotics, such as quinolones, aminoglycosides, macrolides and tetracyclines.
Croatian: Mehanizam djelovanja ertapenema razlikuje se od ostalih skupina antibiotika poput kinolona, aminoglikozida, makrolida i tetraciklina.