FrancophonIA/ELRC3.0 huggingface dataset:
English: Respiratory tract tissue: plasma ratios of 1.3 (healthy lungs), 1.9 (pneumonic lungs) and 2.3 (nasal mucosa) have been reported for doxycycline.
Maltese: Il-passaġġ respiratorju tat-tessut: proporzjonijiet tal-plażma ta' 1.3 (pulmuni b'saħħithom), 1.9 (pulmuni pnewmoniċi) u 2.3 (mukoża tal-imnieħer) ġew irrapportati għad-doxycycline.
English: Excipients: For a full list of excipients, see section 6.1
Maltese: Għal lista sħiħa ta' reċċipjenti, ara sezzjoni 6.1
English: 1 gram of powder contains:
Maltese: 1 gramma ta' trab fih:
English: Chemotherapy 63, 733
Maltese: J Antimicrob. Chemotherapy 63, 6
English: Solubility of doxycycline is pH dependent.
Maltese: Is-solubilità tad-doxycycline huja pH dipendenti.
English: ADVERSE REACTIONS
Maltese: REAZZJONIJIET AVVERSI
English: Denmark Eurovet Animal Health B.V., P.O. 179,
Maltese: Danimarka Eurovet Animal Health B.V., P.O. 179,
English: In human medicine, doxycycline is the treatment of choice for the treatment of acute tracheobronchitis, acute bronchitis and acute bronchiolitis caused by primary bacterial infections (Mycoplasma pneumoniae, Chlamydia pneumoniae) and bacterial superinfections (Pneumococci, Haemophilus spp.).
Maltese: Fil-mediċina umana, doxycycline huwa l-kura tal-għażla għall-kura tat-trakeobronkite akuta, il-bronkite akuta u l-bronkjolite akuta kkawżata minn infezzjonijiet batteriċi primarji (Mycoplasma pneumoniae, Chlamydia pneumoniae) u superinfezzjonijiet batterjali (Pneumococci, Haemophilus spp.).
English: Sachets of 100g, 250g, 500g and 1 kg and 10x 100g in a carton box.
Maltese: Qratas ta' 100g, 250g, 500 gramma u 1 kg u 10x fil-kaxxa tal-kartun.
English: The lack of an epidemiologically based surveillance programme and standardised susceptibility testing methodology complicates interpretation of reports.
Maltese: In-nuqqas ta' programm ta' sorveljanza bbażat fuq mod epidemjoloġiku u metodoloġija standardizzata ta' ittestjar ta' suxxettibilità jikkomplika l-interpretazzjoni tar-rapporti.
English: Tetracycline resistance is usually acquired by means of plasmids or other mobile elements (e.g. conjugative transposones).
Maltese: Ir-reżistenza Tetracycline hija normalment akkwistata permezz ta' plasmidi jew elementi mobbli oħra (eż. transpożoni konjugattivi).
English: Composition per gram product Active Substance:
Maltese: Kompożizzjoni għal gramma tal-prodott Sustanza Attiva:
English: Doxycycline is primarily excreted with the faeces.
Maltese: Id-Doxycycline huwa primarjament eliminat mal-ippurgar.
English: Doxycycline is listed as a “highly important antimicrobial” for human use, and “critically important” for veterinary use according to the WHO criteria, 2007.
Maltese: Doxycycline huwa elenkat bħala “antimikrobiku importanti ħafna” għall-użu fuq il-bniedem, u “kritikament importanti” għall-użu veterinarju skont il-kriterji tad-WHO, 2007.
English: Doxycycline hyclate France: Doxycycline Excipients
Maltese: Doxycycline hyclate FR: Doxycycline Eċipjenti
English: High levels of resistance to tetracyclines in swine respiratory pathogens have been documented (ARBAO-II study, 2008)6.
Maltese: Livelli għoljin ta' reżistenza għat-tetraċiklini fil-patoġeni respiratorji tal-majjali kienu diġà ġew iddokumentati (studju ARBAO-II, 2008)6.
English: Hungary Eurovet Animal Health B.V., P.O. 179,
Maltese: Eurovet Animal Health B.V., P.O. 179,
English: Pigs and chickens (broiler, pullet, breeder).
Maltese: Ħnieżer u tiġieġ (brojler, pullet, min irabbi).
English: Tetracyclines may - in very rare cases - induce photosensitivity and allergic reactions.
Maltese: It-Tetracyclines jistgħu - f'każijiet rari ħafna - jinduċu fotosensittività u reazzjonijiet allerġiċi.
English: Pharmacotherapeutic group: Antibacterial - Tetracycline.
Maltese: Antibatteriċi - Tetraċiklini.
English: MANUFACTURER'S BATCH NUMBER Lot{number}
Maltese: NUMRU TAL-LOTT TAL-MANIFATTUR Lott{numru}
English: Pigs: - Meat and offal: 4 days
Maltese: Ħnieżer: - Laħam u interjuri: 4 ijiem
English: LEAFLET
Maltese: Eċipjenti
English: Doxycycline is a broad-spectrum antibiotic, active against a large number of Gram-positive and Gramnegative, aerobe and anaerobe micro-organisms, Mycoplasmata, Chlamydiae and Rickettsia.
Maltese: Id-Doxycycline hija antibijotiku bi spettru wiesa', attiva kontra numru kbir ta' Gram-pożittivi u Gramnegattivi, aerobe u anaerobe mikro-organiżmi, Mycoplasmata, klamidji u Rickettsia.
English: PACKAGE SIZE 10x100 gram
Maltese: DAQS TAL-PAKKETT 10x100 gram
English: PACKAGE SIZE 100 gram
Maltese: DAQS TAL-PAKKETT 100 gram
English: • Pigs: 12.5 mg doxycycline hyclate (25 mg product) per kg body weight per day for 4
Maltese: • Majjali: 12.5 mg doxycycline hyclate (prodott ta' 25 mg) kull kg tal-piż tal-ġisem kuljum għal 4
English: • Indications;
Maltese: • L-indikazzjonijiet;
English: There have been no reports of adverse events in pigs, including suspected lack of expected efficacy, during the last 5 years.
Maltese: Ma kien hemm l-ebda rapport ta' avvenimenti avversi fil-majjali, inkluż l-issuspettat nuqqas ta' effikaċja mistennija, matul laħħar 5 snin.
English: Doxycycline hyclate 500 mg, corresponding to 433 mg doxycycline France: Doxycycline 433 mg, corresponding to 500 mg doxycycline hyclate
Maltese: Doxycycline hyclate 500 mg, jikkorisspondi għal 433 mg doxycycline FR: Doxycycline 433 mg, jikkorisspondi għal 500 mg doxycycline hyclate
English: 500 mg corresponding to 433 mg doxycycline 433 mg corresponding to 500 mg doxycycline hyclate
Maltese: 500 mg jikkorrispondi għal 433 mg doxycycline 433 mg jikkorrispondi għal 500 mg doxycycline hyclate
English: The Marketing Authorisation Holder has provided evidence that the baseline PK of doxycycline, when delivered orally to pigs at a dose of 12.5 mg/kg body weight will provide plasma levels of 0.71 - 1.14 µg/ml (Pijpers et al (1991) 1.
Maltese: Is-Sid tal-Awtorizzazzjoni tal-Kummerċjalizzazzjoni ipprovda evidenza li l-linja bażi ta' PK ta' doxycycline, meta tingħata b'mod orali lill-majjali f'doża ta' 12.5 mg/kg tal-piż tal-ġisem tipprovdi livelli ta' 0.71 - 1.14 µg/ml fil-plażma (Pijpers et al (1991) 1.
English: J Antimicrob.
Maltese: J. Amer.
English: Doxycycline is primarily a bacteriostatic drug.
Maltese: Id-Doxycycline hija primarjament droga batterjostatika.
English: Significantly no cross resistance was observed between oxytetracycline and doxycycline.
Maltese: B'mod sinifikanti ma kienet osservata l-ebda inter-reżistenza bejn oxytetracycline u doxycycline.
English: • Chickens (broiler, pullet, breeder): 10 mg doxycycline hyclate per kg body weight per day for 3-4 days for the treatment of infections caused by P. multocida and 20 mg doxycycline hyclate per kg body weight per day for 3-4 days for the treatment of infections caused by
Maltese: • Tiġieġ (broiler, pullet, għat-trobbija): 10 mg doxycycline hyclate kull kg tal-piż tal-ġisem kuljum għal 3-4 ijiem għall-kura ta' infezzjonijiet ikkawżati minn P. multocida u 20 mg doxycycline hyclate kull kg tal-piż tal-ġisem kuljum għal 3-4 ijiem għall-kura ta' infezzjonijiet ikkawżati minn O. rhinotracheale.
English: Doxycycline belongs to the group of the tetracycline antibiotics.
Maltese: Id-Doxycycline tappartjeni għall-grupp tal-antibijotiċi tetraċiklini.
English: Tetracyclines have broad spectrum activity inhibiting Gram-positive and Gram-negative bacteria, mycoplasmas, chlamydiae, rickettsias and some protozoa.
Maltese: It-tetraċiklini għandhom attività bi spettru wiesgħa li jinibixxu l-batterji Gram-pożittivi u Gram-negattivi, ilmikroplażmi, klamidji, rickettsias u xi protozoa.
English: Four resistance mechanisms acquired by microorganisms against tetracyclines in general have been reported: Decreased accumulation of tetracyclines (decreased permeability of the bacterial cell wall and active efflux), protein protection of the bacterial ribosome, enzymatic inactivation of the antibiotic and rRNA mutations (preventing the tetracycline binding to ribosome).
Maltese: Erba' mekkaniżmi ta' reżistenza miksuba minn mikroorganiżmi kontra tetracyclines b'mod ġenerali ġew rappurtati: akkumulazzjoni imnaqqsa ta' tetracyclines (li ixekkel il-permeabilità tal-ħajt taċ-ċellula batterjali u l-effluss attiv), il-protezzjoni tal-proteina tal-batterji ribosoma, inattivazzjoni enżimatika talmutazzjonijiet antibijotiċi u tal-rRNA (prevenzjoni tal-tetraċiklina li laqbad mar-ribosoma).
English: 2 Bousquet et al. 1998, Pharmacokinetics of doxycycline in pigs following oral administration in feed Vet.Res.
Maltese: 2 Bousquet et al. 1998, Pharmacokinetics of doxycycline in pigs following oral administration in feed Vet.Res. 29 , 475-485 3 Bousquet E., Morvan H., Aitken I., Morgan J.
English: It was agreed that the target species should be harmonised across all Member States where the product is authorised or pending authorisation and in consistency with the recent Article 35 harmonisation as “chickens (broiler, pullet, breeder)”, and the following indications for Doxyfar 50% and associate names were agreed:
Maltese: Ġie miftiehem li l-ispeċi fil-mira għandhom jiġu armonizzati madwar l-Istati Membri kollha fejn ilprodott huwa awtorizzat jew qiegħed jistenna l-awtorizzazzjoni u b'mod konformi mal-armonizzazzjoni riċenti tal-Artikolu 35 bħala “tiġieġ (brojler, pullet, għat-trobbija)”, u l-indikazzjonijiet segwenti għal Doxyfar 50% u l-ismijiet assoċjat ġew miftiehma:
English: Doxycycline is scarcely metabolised.
Maltese: Id-Doxycycline hija ftit metabolizzata.
English: Following oral administration at a dose of 12.8 mg/kg body weight, steady state concentrations during medication range between a Cmin of 0.40 µg/ml in the early morning to a Cmax of 0.87 µg/ml in the late afternoon in pigs.
Maltese: Wara l-għoti orali b'doża ta' 12.8 mg/kg, konċentrazzjonijiet fi stat stabbli matul medda medikazzjoni bejn Cmin ta' 0,40µg/ml fil-għodu kmieni għal Cmax ta' 0.87µg/ml tard wara nofsinhar fil-majjali.
English: OTHER INFORMATION Pack sizes: 100g, 10x 100g, 250g, 500g and 1 kg Not all pack sizes may be marketed.
Maltese: INFORMAZZJONI IEĦOR Daqsijiet tal-pakkett: 100g, 10x 100g, 250g, 500g u 1 kg Mhux id-daqsijiet tal-pakketti kollha jistgħu jitpoġġew fis-suq
English: Chickens: Where clinical disease is present in the flock, to reduce mortality, morbidity, and clinical signs and to reduce lesions due to Pasteurellosis caused by Pasteurella multocida or to reduce morbidity and lesions in respiratory infections caused by Ornithobacterium rhinotracheale (ORT).
Maltese: Fejn mard kliniku huwa preżenti fil-merħla, sabiex titnaqqas il-mortalità, morbidità, u sinjali kliniċi u jitnaqqsu leżjonijiet minħabba Pasteurellosis ikkawżata minn Pasteurella multocida jew sabiex inaqqsu l-morbidità u leżjonijiet fl-infezzjonijiet respiratorji kkawżati minn Ornithobacterium rhinotracheale (ORT).
English: In the absence of compatibility studies, this product must not be mixed with other veterinary medicinal products.
Maltese: Fin-nuqqas ta' studji ta' kompatibilità, dan il-prodott m'għandux jitħallat ma' prodotti mediċinali veterinarji oħra.
English: Do not combine with antibiotics that are bacteriocidal e.g. penicillins or cephalosporins.
Maltese: Tikkombinax ma' antibijotiċi li huma bacterioċidali eż peniċillini jew cephalosporini.
English: Greece
Maltese: Ungerija
English: Wear impermeable gloves (e.g. rubber or latex) and an appropriate dust mask (e.g. disposable half-mask respirator conforming to European Standard EN149) when applying the product.
Maltese: Ilbes ingwanti impermeabbli (eż. lastku jew il-latex) u maskla xierqa għat-trab (eż. li jintremew ta' nofs maskla li jikkonforma mar-respiratur Ewropea EN149 Standard) meta tapplika l-prodott.
English: Soludox 50% Doxycycline hyclate 500 mg/g
Maltese: Soludox 50% Doxycycline hyclate 500 mg/g trab għall-użu fl-ilma tax-xorb
English: Further the Marketing Authorisation Holder has also provided evidence (Bousquet et al. 1998)2 that doxycycline will concentrate in nasal secretions and if fed at dose regimens between 11.8 -13.3 mg/kg body weight for 1 hour per day concentrations of between 0.7 and 1 µg/ml are achieved in the lung and nasal concentrations of 1.7 +/- 0.4 µg/ml are reached.
Maltese: Barra minn hekk is-Sid tal-Awtorizzazzjoni tal-Kummerċjalizzazzjoni ipprovda wkoll evidenza (Bousquet et al. 1998)2 li doxycycline jikkonċentra fit-tnixxijiet nażali u jekk jingħata f'reġimens ta' doża bejn 11.8 -13.3 mg/kg tal-piż tal-ġisem għal siegħa kuljum jintlaħqu konċentrazzjonijiet ta' bejn 0.7 u 1 µg/ml fil-pulmun u konċentrazzjonijiet nażali ta' 1.7 +/- 0.4 µg/ml.
English: SPECIAL WARNINGS
Maltese: INFORMAZZJONI IEĦOR
English: mg product / kg body weight / day x
Maltese: ..... mg tal-prodott / kg piż tal-ġisem kuljum x
English: 12.5 mg doxycycline hyclate (25 mg product) per kg body weight per day for 4 consecutive days.
Maltese: 12.5 mg doxycycline hyclate (25 mg tal-prodott) għal kull kg piż tal-ġisem kuljum għal 4 ijiem konsekuttivi.
English: Following administration of doxycycline hyclate at an actual dose of 10 mg/kg body weight steady state plasma concentrations ranged from 0.75 to 0.93 µg/g between 12 and 96 hours after start of medication.
Maltese: Wara l-għoti tad-doxycycline hyclate f'doża attwali ta' 10 mg/kg bw konċentrazzjonijiet stabbli fil-plażma varjaw stat 0.75-0.93 µg/g bejn 12 u 96 siegħa wara l-bidu tal-medikazzjoni.
English: DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION
Maltese: METODU U ROTTA(OT) TA' AMMINISTRAZZJONI
English: Carton box for the 10x100 grams Alufoil sachets with label for 100 gram sachets and leaflet
Maltese: Kaxxa tal-kartun għall-qratas Alufoil tal-10x100 grammi Bit-tikketta għall-qratas tal-100 gramma u l-fuljett
English: Pigs Chickens
Maltese: TAL-PRODOTTI MHUX
English: The chicken meat residue depletion data for both dosing regimens (10 mg doxycycline hyclate per kg body weight per day for 4 days and 20 mg doxycycline hyclate per kg body weight per day for 4 days) were submitted.
Maltese: Ġiet sottomessa dejta dwar it-tnaqqis fir-residwi fil-laħam tat-tiġieġ għaż-żewġ reġimens ta' dożaġġ (10 mg doxycycline hyclate kull kg tal-piż tal-ġisem għal 4 ijiem u 20 mg doxycycline hyclate kull kg tal-piż tal-ġisem għal 4 ijiem).
English: When pigs are administered 12.5 mg doxycycline hyclate/kg bw/day for 8 days; meat withdrawal periods of 4 days will ensure consumer safety.
Maltese: Meta l-majjali jingħataw 12.5 mg doxycycline hyclate/kg bw/kuljum għal 8 ijiem; il-perjodi tal-irtirar ta' 4 ijiem għal-laħam jassiguraw is-sigurtà lill-konsumatur.
English: These antibiotics have a broad spectrum of antimicrobial activity, sharing the same basic structure of polycyclic naphthacenecarboxamide.
Maltese: Dawn l-antibijotiċi għandhom spettru wiesgħa ta' attività antimikrobjali, li jaqsmu l-istess struttura bażika ta' naphthacenecarboxamide poliċikliċi.
English: 5.2 Pharmacokinetic properties
Maltese: 3. GĦAMLA FARMAĊEWTIKA
English: TARGET SPECIES Pigs and chickens (broiler, pullet, breeder).
Maltese: SPEĊI FIL-MIRA Ħnieżer u tiġieġ (brojler, pullet, min irabbi).
English: The following indications for Doxyfar 50% and associate names were agreed:
Maltese: Sar qbil fuq l-indikazzjonijiet segwenti għal Doxyfar 50% u l-ismijiet assoċjati:
English: Overall summary of the scientific evaluation of Doxyfar 50% and associated names (see annex I)
Maltese: Sommarju ġenerali tal-evalwazzjoni xjentifika ta' Doxyfar 50% u l-ismijiet assoċjati (ara anness I)
English: O. rhinotracheale.
Maltese: Isem kummerċjali
English: No data have been provided for chickens, however the Marketing Authorisation Holder submitted in support of the recent Article 35 referral for all strengths of water soluble powders and oral solutions containing doxycycline hyclate indicated for use in poultry and intended for administration via the drinking water (EMEA/V/A/047).
Maltese: Preċedentement kienet ġiet sottomessa dejta bħala parti mir-referenza riċenti għall-Artikolu 35 għallqawwiet kollha tat-trab li jinħall fl-ilma u għas-soluzzjonijiet orali li fihom doxycycline hyclate indikati għall-użu fit-tjur u intiżi għall-għoti permezz tal-ilma tax-xorb (EMEA/V/A/047).
English: It was identified at the time of the Article 35 referral for water soluble powders and oral solutions containing doxycycline hyclate that a high resistance rate to tetracyclines existed in E. coli isolated from chickens (De Jong et al, 2009)5.
Maltese: Fil-ħin tarreferenza għall-Artikolu 35 dwar it-trab li jinħall fl-ilma u s-soluzzjonijiet orali li fihom doxycycline hyclate ġie identifikat li fl-E. coli iżolat mit-tiġieġ kienet teżisti rata ta' reżistenza għolja għattetraċiklini (De Jong et al, 2009)5.
English: Due to the divergent national decisions taken by Member States concerning the authorisation of Doxyfar 50 % and associated names, the issue was referred to CVMP under Article 34(1) of Directive 2001/82/EC, in order to resolve divergences amongst the nationally authorised Summary of Product Characteristics (SPC) across the European Union.
Maltese: Minħabba d-deċiżjonijiet nazzjonali diverġenti li ttieħdu mill-Istati Membri dwar l-awtorizzazzjoni ta' Doxyfar 50 % u tal-ismijiet assoċjati, il-kwistjoni ġiet riferuta lis-CVMP skont l-Artikolu 34(1) tadDirettiva 2001/82/KE, biex jiġu riżolti d-diverġenzi fost is-Sommarji tal-Karatteristiċi tal-Prodott (SPC) li huma awtorizzati fuq livell nazzjonali madwar l-Unjoni Ewropea.
English: If the same feed is provided ad libitum throughout the day the lung concentration rises to 2.9 +/- 0.6 µg/ml.
Maltese: Jekk l-istess għalf jingħata ad libitum matul il-ġurnata, ilkonċentrazzjonijiet fil-pulmun jogħlew għal 2.9 +/- 0.6 µg/ml.
English: The following recommended dose for Doxyfar 50% and associate names was agreed:
Maltese: Sar qbil fuq id-doża rakkomandata li ġejja għal Doxyfar 50% u l-ismijiet assoċjati:
English: Belgium Eurovet N.V. Poorthoevestraat 4, 3 550 Heusen-Zolder Belgium
Maltese: Poorthoevestraat 4, 3 550
English: Pigs: For the treatment of the clinical signs associated with porcine respiratory disease caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae susceptible to doxycycline.
Maltese: Għat-trattament tas-sinjali kliniċi assoċjati mal-marda respiratorja fil-majjali kkawżata minn Actinobacillus pleuropneumoniae, Pasteurella multocida, u Mycoplasma hyopneumoniae u suxxettibbli għal doxycycline.
English: None.
Maltese: Vet.
English: - Meat and offal: 12 days, following a dose rate of 20 mg/kg body weight for 4 days.
Maltese: - Laħam u interjuri: 12-il jum, wara rata ta' doża ta' 20 mg/kg piż tal-ġisem għal 4 ijiem.
English: The pig meat residue depletion data was made available and supported a meat withdrawal period of 4 days when pigs are administered 12.5 mg doxycycline hyclate/kg body weight/day for up to 8 days.
Maltese: Id-dejta dwar it-tnaqqis fir-residwi fil-laħam tal-majjali tpoġġiet għad-dispożizzjoni u appoġġat perjodu ta' rtirar ta' 4 ijiem għal-laħam meta l-majjali jingħataw 12.5 mg doxycycline hyclate/kg tal-piż talġisem /kuljum sa massimu ta' 8 ijiem.
English: Doxycycline increases the action of anticoagulants.
Maltese: Id-Doxycycline iżżid l-azzjoni tal-antikoagulanti.
English: The Marketing Authorisation Holder provided persuasive argument that in the field differentiation between Pasteurellosis and O. rhinotracheale in poultry could be readily achieved.
Maltese: Is-Sid talAwtorizzazzjoni tal-Kummerċjalizzazzjoni ipprovda argument konvinċenti li fil-qasam, id-distinzjoni bejn Pasteurellosis u O. rhinotracheale fit-tjur setgħet tinkiseb faċilment.
English: The precautions to limit the development of resistance, which were recommended by CVMP during the Article 35 referral, have been included in section 4.5 of the SPC.
Maltese: Il-ġestjoni tar-riskju jew miżuri ta' mitigazzjoni Il-prekawzjonijiet biex jiġi limitat l-iżvilupp ta' reżistenza, li ġew irrakkomandati mis-CVMP waqt irreferenza għall-Artikolu 35, ġew inklużi f'sezzjoni 4.5 tal-SPC.
English: In case of severe infections the medication period may be prolonged for a maximum of 8 consecutive days as determined by the attending veterinary surgeon.
Maltese: Fil-każ ta' infezzjonijiet severi il-perjodu ta' medikazzjoni jista' jiġi mtawwal għal massimu ta' 8 ġranet konsekuttivi kif determinat mill-kirurgu veterinarju li jattendi.
English: Water Soluble Powder for oral administration
Maltese: PARIR DWAR L-AMMINISTRAZZJONI KORRETTA
English: Benefit Risk assessment
Maltese: Valutazzjoni tar-Riskju
English: Doxycycline (as hyclate) 433 mg/g
Maltese: Doxycycline (as hyclate) 433 mg/g trab għall-użu fl-ilma tax-xorb
English: Chickens: - Meat and offal: 3 days, following a dose rate of 10 mg/kg body weight for 4 days.
Maltese: - Laħam u interjuri: 3 ijiem, wara rata ta' doża ta' 10 mg/kg piż tal-ġisem għal 4 ijiem.
English: Data were provided in support of the indication for P. multocida at a dose of 10 mg doxycycline hyclate per kg body weight per day.
Maltese: Ġiet ipprovduta dejta b'appoġġ għall-indikazzjoni għal P. multocida f'doża ta' 10 mg doxycycline hyclate kull kg tal-piż talġisem kuljum.
English: A chicken meat withdrawal period of 3 days when chickens are treated with 10 mg doxycycline hyclate/kg bw/day for 4 days; and a meat withdrawal period of 12 days when the chicken are treated with 20 mg doxycycline hyclate/kg bw/day for 4 days can be accepted.
Maltese: doxycycline hyclate/kg bw/kuljum għal 4 ijiem; u perjodu ta' rtirar ta' 12-il ġurnata għal-laħam meta ttiġieġ ikunu rċevew kura b'20 mg doxycycline hyclate/kg bw/kuljum għal 4 ijiem jistgħu jiġu aċċettati.
English: Doxyfar 50 % and associated names is a powder for use in drinking water containing the active substance doxycycline hyclate 500 mg/g.
Maltese: Doxyfar 50 % u l-ismijiet assoċjati huwa trab għall-użu fl-ilma tax-xorb li fih is-sustanza attiva doxycycline hyclate 500 mg/g. Doxycycline huwa antibijotiku tetraċiklin semi-sintetiku.
English: LABEL TEXT SINGLE SACHETS/BAGS
Maltese: TEST TAT-TIKKETTA QARTAS WAĦDIENI / BOROS
English: Poultry tolerate double overdoses of doxycycline (40 mg/kg body weight) without any clinical effect.
Maltese: Tjur jittolleraw dożi eċċessivi doppji ta' doxycycline (40 mg/kg) mingħajr lebda effett kliniku.
English: On the basis of well established use and absence of data for suspected lack of expected efficacy the dose regimen for infections caused by P. multocida of 10 mg doxycycline hyclate per kg body weight for 3 to 4 consecutive days and for infections caused by O. rhinotracheale of 20 mg doxycycline hyclate per kg body weight for 3 to 4 consecutive days were considered acceptable.
Maltese: Fuq bażi tal-użu stabbilit sew u n-nuqqas ta' dejta għan-nuqqas issuspettat ta' effikaċja mistenni, ir-reġimen tad-doża għallinfezzjonijiet ikkawżati minn P. multocida ta' 10 mg doxycycline hyclate kull kilogramm tal-piż talġisem għal 3 sa 4 ijiem konsekuttivi u għall-infezzjonijiet ikkawżati minn O. rhinotracheale ta' 20 mg doxycycline hyclate kull kg tal-piż tal-ġisem għal 3 sa 4 ijiem konsekuttivi kien ikkunsidrat bħala aċċettabbli.
English: Pig
Maltese: OĦRA
English: Residue depletion data in pigs support a meat withdrawal period of 4 days when pigs are administered at 12.5 mg doxycycline hyclate/kg body weight/day for up to 8 days.
Maltese: Dejta dwar it-tneħħija tar-residwi fil-majjali tappoġġa perjodu ta' rtirar ta' 4 ijiem għal-laħam meta lmajjali jingħataw doża ta' 12.5 mg doxycycline hyclate/kg tal-piż tal-ġisem/kuljum sa massimu ta' 8 ijiem.
English: Plasma protein binding is high (over 90%).
Maltese: L-irbit fil-plażma mal-proteini hija għolja (aktar minn 90%).
English: 20 mg doxycycline hyclate (40 mg product) per kg body weight per day for 3-4 consecutive days in case of infections caused by O. rhinotracheale
Maltese: 10 mg doxycycline hyclate (20mg tal-prodott) għal kull kg piż tal-ġisem kuljum għal bejn 3-4 ijiem konsekuttivi fil-każ ta' infezzjonijiet ikkawżati minn P. multocida u 20 mg doxycycline hyclate (40 mg tal-prodott) kull kg piż tal-ġisem kuljum għal bejn 3-4 ijiem konsekuttivi fil-każ ta' infezzjonijiet ikkawżati minn O. rhinotracheale
English: Precipitation will occur in an alkaline solution.
Maltese: Il-preċipitazzjoni sseħħ f'soluzzjoni alkalina.