FrancophonIA/ELRC3.0 huggingface dataset:
English: It is important that patients start to breathe in as slowly as possible just before operating their inhaler.
Estonian: Tähtis on sissehingamist alustada nii aeglaselt kui võimalik enne inhalaatori kasutamist.
English: If you are allergic (hypersensitive) to salmeterol xinafoate, fluticasone propionate or to the other ingredient Norflurane (HFA 134a).
Estonian: Kui te olete allergiline (ülitundlik) salmeteroolksinafoaadi, flutikasoonpropionaadi või norfluraani (HFA 134a) suhtes.
English: If Viani therapy has to be withdrawn due to overdose of the beta agonist component of the drug, provision of appropriate replacement steroid therapy should be considered.
Estonian: Kui VIANI-ravi jäetakse ära ravimi βagonist komponendi üleannustamise tõttu, tuleb kaaluda steroidkomponendi asendust.
English: Viani Evohaler should be discontinued immediately, the patient assessed and alternative therapy instituted if necessary.
Estonian: VIANI kasutamine tuleb otsekohe lõpetada, hinnata patsiendi seisundit ning vajadusel rakendada alternatiivset ravi.
English: GlaxoSmithKline SA Parque Tecnologico de Madrid, Calle Severo Ochoa 2, 28760 Tres Cantos, Madrid Spain
Estonian: GlaxoSmithKline SA Parque Tecnologico de Madrid, Calle Severo Ochoa 2, 28760, Tres Cantos, Madrid, Hispaania
English: Instructions for Use:
Estonian: Kasutusjuhend:
English: The time on treatment for 50% of subjects to achieve a first individual Well-Controlled week was 16 days for Viani compared to 37 days for the ICS group.
Estonian: Ravi kestus, mille jooksul 50% uuritavatest saavutab esimese individuaalse hea kontrolliga nädala, oli VIANI puhul 16 päeva ja inhaleeritava kortikosteroidi puhul 37 päeva.
English: Therefore, it must be taken every day as directed by your doctor.
Estonian: Seepärast tuleb ravimit manustada iga päev vastavalt arsti ettekirjutustele.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 120 puffs
Estonian: PAKENDI SISU KAALU, MAHU VÕI ÜHIKUTE JÄRGI 120 annust
English: Care should be taken when transferring patients to Viani therapy, particularly if there is any reason to suppose that adrenal function is impaired from previous systemic steroid therapy.
Estonian: Patsientide üleviimine VIANI-ravile peab toimuma ettevaatusega, eriti kui on põhjust arvata, et neerupealiste funktsioon on eelneva süsteemse hormoonravi poolt pärsitud.
English: Viani 25/50 micrograms strength is not appropriate in adults and children with severe asthma; it is recommended to establish the appropriate dosage of inhaled corticosteroid before any fixed combination can be used in patients with severe asthma.
Estonian: VIANI 25/50 mikrogrammine tugevus ei sobi raske astmaga täiskasvanutele ja lastele; enne ükskõik millise fikseeritud kombinatsiooni kasutamist raskekujulise astmaga patsientidel on soovitatav kindlaks määrata inhaleeritava glükokortikosteroidi sobiv annus.
English: Norflurane (HFA 134a).
Estonian: Norfluraan (HFA 134a).
English: If your symptoms are well controlled using Viani Evohaler twice daily, your doctor may decide to reduce your dose to once daily.
Estonian: Kui haigusnähud on hästi kontrollitud Viani Evohaler'i kaks korda ööpäevas kasutamisel, võib arst vähendada manustamise sagedust ühe korrani ööpäevas.
English: Viani Evohaler is for inhalation use only.
Estonian: Viani Evohaler'it manustatakse ainult inhaleerimise (sissehingamise) teel.
English: If your asthma gets worse or is not well controlled (you will feel wheezy and need more of your fast acting ‘rescue' medicine), do not increase the number of puffs of Viani you take.
Estonian: Kui astma muutub raskemaks või te tunnete, et haigus ei ole kontrolli all (hingeldus süveneb ning te vajate järjest sagedamini hooravimi sissehingamist), ärge suurendage ise Viani sissehingatavate annuste arvu.
English: A subpopulation from the GOAL study (Gaining Optimal Asthma ControL study) i.e. stratum 1, addendum, step 1 (patients without ICS at entry who fulfilled the criteria for moderate persistent asthma and who are randomised to Viani 50/100 or FP 100 mcg), can be considered as an adequate target population to assess the adequacy of Viani as IMT.
Estonian: GOAL uuringu (Gaining Optimal Asthma ControL study) alampopulatsioone, nt 1. kihti, lisarühma ja 1. astet (uuringusse kaasamisel ilma ICS-ta patsiendid, kes vastasid tingimustele mõõduka persistentse astma osas ning kes jaotati juhuslikkuse alusel Viani 50/100 või flutikasoonpropionaadi 100 mcg rühma), võib käsitada sobiva sihtpopulatsioonina hindamaks Vianiasjakohasust esmaseks säilitavaks raviks.
English: The suspension is contained in an internally lacquered, 8ml aluminium alloy pressurised container sealed with a metering valve.
Estonian: Suspensioon on mõõteklapiga seest lakitud 8 ml alumiiniumsulamist rõhukonteineris.
English: It should be noted that this could potentially lead to an increase in the risk of systemic adverse effects.
Estonian: Sellega võib kaasneda süsteemsete kõrvaltoimete riski suurenemine.
English: The number will show through a window at the back of the plastic casing.
Estonian: See arv on näha plastmasskorpuse tagaküljel olevas aknas.
English: The main part of the dose is excreted as faeces as metabolites and unchanged drug.
Estonian: Põhiosa annusest eritub roojaga metaboliitidena ja muutumatul kujul.
English: The maximum licensed dose of fluticasone propionate delivered by Viani inhaler in children is 100mcg twice daily.
Estonian: VIANI EVOHALER'ist manustatud flutikasoonpropionaadi maksimaalne lubatud annus lastele on 100 µg kaks korda ööpäevas.
English: Patients should continue holding their breath for as long as is comfortable.
Estonian: Patsiendid peavad hinge kinni hoidma seni kuni on mugav ning seejärel aeglaselt välja hingama.
English: Children and adolescents <16years taking high doses of fluticasone (typically ≥ 1000mcg/day) may be at particular risk.
Estonian: Eriti ohustatud on lapsed ja alla 16-aastased noorukid, kes saavad flutikasooni suuri annuseid (tüüpiliselt ≥1000 µg ööpäevas).
English: Your doctor will supervise your treatment more closely if you have medical conditions such as heart disease including an irregular or fast heart beat, overactive thyroid gland, high blood pressure, diabetes mellitus (Viani may increase your blood sugar), low potassium in your blood or if you are being, or have been treated for have tuberculosis (TB).
Estonian: Teie arst jälgib teie ravi eriti põhjalikult, kui teil on mõni järgnevatest haigustest: südamehaigus, sh ebaregulaarne või kiire südametegevus, kilpnäärme ületalitlus, kõrge vererõhk, suhkurtõbi (Viani võib tõsta veresuhkru taset), madal kaaliumisisaldus veres või kui saate või olete saanud ravi tuberkuloosi vastu.
English: Very rare cases of adrenal suppression and acute adrenal crisis have also been described with doses of fluticasone propionate between 500 and less than 1000mcg.
Estonian: Väga harvadel juhtudel on neerupealiste supressiooni ja ägedat adrenaalkriisi kirjeldatud ka flutikasoonpropionaadi 500....1000 µg annuste puhul.
English: The results of this study suggest that Viani 50/100mcg bd may be considered as initial maintenance therapy in patients with moderate persistent asthma for whom rapid control of asthma is deemed essential (see section 4.2).
Estonian: Uuringu tulemused näitavad, et VIANI EVOHALERI´t annuses 50/100 mikrogrammi päevas, võib kasutada mõõduka persisteeruva astma esmaseks püsiraviks patsientidel, kellel kiire astma kontrolli alla saamist peetakse väga oluliseks (vt lõik 4.2).
English: Replace the inhaler when the counter reads 000.
Estonian: Vahetage inhalaator uue vastu, kui annuselugeja näit on 000.
English: A twelve month study (Gaining Optimal Asthma ControL, GOAL), in 3416 adult and adolescent patients with persistent asthma, compared the safety and efficacy of Viani versus inhaled corticosteroid (Fluticasone Propionate) alone to determine whether the goals of asthma management were achievable.
Estonian: 12-kuulises uuringus (Gaining Optimal Asthma ControL, GOAL), kus osales 3416 püsiva astmaga täiskasvanut ja noorukit, võrreldi VIANI ja ainult inhaleeritava kortikosteroidi (flutikasoonpropionaadi) efektiivsust ja ohutust astma ravieesmärkide saavutamisel.
English: 1 x 120 actuations Inhaler or 3 x 120 actuations Inhaler or 10 x 120 actuations Inhaler - hospital/pharmacy use only (for dispensing purposes) Not all pack sizes may be marketed.
Estonian: 10 x 120 annust inhalaatoris - saadaval haiglatele/apteekidele Kõik pakendi suurused ei pruugi olla müügil.
English: Stop using the inhaler when the counter reads 000.
Estonian: Lõpetage inhalaatori kasutamine, kui annuselugeja näit on 000.
English: 3 X 120 puffs
Estonian: 3 X 120 annust
English: This is equivalent to 21 micrograms of salmeterol and 44, 110 or 220 micrograms of fluticasone propionate delivered from the actuator (delivered dose).
Estonian: See vastab 21 µg salmeteroolile ja 44, 110 või 220 µg flutikasoonpropionaadile (inhalaatorist vabanev annus).
English: The absolute bioavailability of inhaled fluticasone propionate in healthy subjects varies between approximately 10-30% of the nominal dose depending on the inhalation device used.
Estonian: Ravimi manustamisel inhalatsiooni teel on flutikasoonpropionaadi absoluutne biosaadavus tervetel inimestel 10…30%, sõltuvalt kasutatud inhalaatorist.
English: As systemic absorption is largely through the lungs, the use of a spacer plus metered dose inhaler may increase drug delivery to the lungs.
Estonian: Kuna süsteemne imendumine toimub suurel määral kopsude kaudu, võib vahemahuti kasutamine koos inhalaatoriga suurendada ravimi kopsudesse jõudmist.
English: GOAL showed more patients treated with Viani achieved asthma control than patients treated with ICS alone and this control was attained at a lower corticosteroid dose.
Estonian: GOAL uuring näitas, et kontrolli astma üle saavutas rohkem VIANI´t kui ainult inhaleeritavat kortikosteroidi saanud patsiente ning see kontroll saavutati väiksema kortikosteroidi annusega.
English: Situations, which could potentially trigger acute adrenal crisis, include trauma, surgery, infection or any rapid reduction in dosage.
Estonian: Ägeda adrenaalkriisi võivad vallandada näiteks trauma, operatsioon, infektsioon või annuse kiire vähendamine.
English: Patients should remove the mouthpiece cover by gently squeezing the sides of the cover and check the mouthpiece inside and outside to see that it is clean.
Estonian: Patsiendid peavad eemaldama huuliku katte, vajutades selle külgedele, ning kontrollima huulikut seest- ja väljastpoolt, kas see on puhas.
English: In addition there are only limited data available on the pharmacokinetics of salmeterol because of the technical difficulty of assaying the drug in plasma due to the low plasma concentrations at therapeutic doses (approximately 200 picogram/ml or less) achieved after inhaled dosing.
Estonian: Salmeterooli farmakokineetika kohta on andmed puudulikud, kuna inhaleeritava terapeutilise annuse puhul on ravimi kontsentratsioon plasmas madal (ligikaudu 200 pg/ml või vähem).
English: If they see "mist" coming from the top of their inhaler or the sides of their mouth they should start again from stage 2.
Estonian: Kui inhalaatori ülaosast või suunurkadest tuleb „auru”, alustada uuesti punktist 2.
English: The inhaler has been designed for use in a vertical position.
Estonian: Inhalaator on ette nähtud kasutamiseks püstises asendis.
English: The recommendation included in section 4.2 allows a short term trial of Viani Evohaler in adults and adolescents with moderate persistent asthma for whom rapid control of asthma is essential.
Estonian: Punktis 4.2 esitatud soovitus võimaldab Viani Evohaleri lühiajalist testimist mõõduka persistentse astmaga täiskasvanutel ja noorukitel, kelle puhul on väga oluline allutada astma kiiresti ravile.
English: Children 4 to 12 years of age Viani 25/50 Evohaler
Estonian: 4...12-aastased lapsed Viani 25/50 Evohaler
English: Symptomatic candidiasis can be treated with topical antifungal therapy whilst still continuing with the Viani Evohaler.
Estonian: Sümptomaatilist kandidoosi võib ravida lokaalsete seentevastaste ravimitega, jätkates samal ajal ravi VIANI'ga.
English: The canister has a counter attached to it, which shows how many actuations of medicine are left.
Estonian: Mahuti on varustatud annuselugejaga, mis näitab, mitu ravimiannust on veel kasutamata.
English: Administration of Viani to pregnant women should only be considered if the expected benefit to the mother is greater than any possible risk to the foetus.
Estonian: VIANI kasutamine raseduse ajal tuleb kõne alla vaid juhul, kui oodatav kasu emale on suurem kui võimalikud ohud lootele.
English: There are no data available for use of Viani inhaler in children aged under 4 years.
Estonian: Puuduvad andmed ravimi kasutamise kohta alla 4-aastastel lastel.
English: Potentially serious hypokalaemia may result from systemic beta-2-agonist therapy, but following inhalation at therapeutic doses plasma levels of salmeterol are very low.
Estonian: β-2-adrenomimeetikumide kasutamisel võib tekkida potentsiaalselt raskekujuline hüpokaleemia, kuid terapeutiliste annuste inhaleerimise järgselt on salmeterooli sisaldus plasmas väga väike.
English: Viani Evohaler and associated names (see Annex I of Opinion) contain salmeterol and fluticasone propionate, a fixed dose combination of the long acting β-agonist (LABA) salmeterol and the inhaled corticosteroid (ICS) fluticasone propionate (FP) indicated in the regular treatment of asthma where use of a combination product (long-acting beta-2-agonist and inhaled corticosteroid) is appropriate:patients not adequately controlled with inhaled corticosteroids and ‘as needed' inhaled short acting beta-2-agonist or - patients already adequately controlled on both inhaled corticosteroid and longacting beta-2-agonist.
Estonian: Viani Evohaler ja sarnased nimetused (vt arvamuse I lisa) sisaldavad salmeterooli ja flutikasoonpropionaati - pika toimeajaga beetaagonisti (LABA) salmeterooli ja sissehingatava kortikosteroidi (ICS) flutikasoonpropionaadi (FP) fikseeritud dooside kombinatsiooni, mis on näidustatud astma tavaraviks, kui liittoote (pika toimeajaga beeta2-agonist ja sissehingatav kortikosteroid) kasutamine on asjakohane: - patsientidel, kes ei allu hästi ravile sissehingatavate kortikosteroididega ja „vajadusel“ lühikese toimeajaga sissehingatava beeta2-agonistiga; võipatsientidel, kes alluvad juba tõestatult hästi ravile sissehingatavate kortikosteroidi ja pika toimeajaga beeta2-agonistiga manustatuna koos.
English: Patients should hold the inhaler upright between fingers and thumb with their thumb on the base, below the mouthpiece.
Estonian: Patsiendid peavad hoidma inhalaatorit püstises asendis sõrmede ja pöidla vahel (pöial on inhalaatori põhjal huuliku all).
English: Take care not to drop the inhaler as this may cause the counter to count down.
Estonian: Ärge pillake inhalaatorit maha, kuna sellisel juhul võib annuselugeja veel ühe annuse maha arvestada.
English: Do not puncture, break or burn it even if you think it is empty.
Estonian: Seda ei tohi avada, lõhkuda ega põletada, isegi kui see on tühi.
English: As with all inhaled medication containing corticosteroids, Viani should be administered with caution in patients with pulmonary tuberculosis.
Estonian: Nagu ka teiste inhaleeritavate glükokortikosteroidide puhul, tuleb ettevaatlik olla ravimi manustamisel kopsutuberkuloosiga patsientidele.
English: There is no need to adjust the dose in elderly patients or in those with renal impairment.
Estonian: Patsientide erigrupid: Vanuritel ja neerupuudulikkusega patsientidel ei ole vaja annust muuta.
English: Viani should be administered with caution in patients with severe cardiovascular disorders, including heart rhythm abnormalities, diabetes mellitus, untreated hypokalaemia or thyrotoxicosis.
Estonian: Ettevaatusega tuleb VIANI´t manustada raskete südame-veresoonkonna häirete (sh südame rütmihäirete), suhkurtõve, ravimata hüpokaleemia või türeotoksikoosi korral.
English: If patients are going to take a second puff they should keep the inhaler upright and wait about half a minute before repeating steps 2 to 6.
Estonian: Enne teise annuse inhaleerimist tuleb hoida inhalaatorit püstises asendis, oodata pool minutit ja korrata punkte 2-6.
English: As with most inhaled medicinal products in pressurised containers, the therapeutic effect of this medicinal product may decrease when the container is cold.
Estonian: Nagu teiste aerosoolide puhul, võib ravimi ravitoime väheneda, kui balloon on külm.
English: Before using for the first time patients should remove the mouthpiece cover by gently squeezing the sides of the cover, shake the inhaler well, and release puffs into the air until the counter reads 120 to make sure that it works.
Estonian: Enne inhalaatori esmakordset kasutamist tuleb eemaldada huuliku kate, vajutades selle külgedele, loksutada inhalaatorit korralikult ja pihustada ravimit õhku, kuni annuselugejal on näit 120, et kontrollida, kas inhalaator töötab.
English: SPECIAL STORAGE CONDITIONS Do not store above 25°C
Estonian: Hoida temperatuuril kuni 25°C
English: Never try to alter the numbers on the counter or detach the counter from the metal can.
Estonian: Ärge kunagi proovige muuta annuselugeja näitu või annuselugejat metallmahuti küljest eemaldada.
English: You should be standing or sitting whilst using the inhaler.
Estonian: Inhalaatori kasutamise ajal istuge või seiske.
English: There is also an increased risk of systemic side effects when combining fluticasone propionate with other potent CYP3A inhibitors (see 4.5 Interaction with Other Medicinal Products and Other Forms of Interaction).
Estonian: Süsteemsete kõrvaltoimete tekke risk suureneb ka flutikasoonpropionaadi kombineerimisel teiste tugevatoimeliste CYP3A inhibiitoritega (vt ka lõik
English: Patients should be instructed in the proper use of their inhaler (see patient information leaflet) During inhalation, the patient should preferably sit or stand.
Estonian: Ravimi inhaleerimise ajal peaks patsient eelistatult istuma või seisma.
English: Consideration should be given to additional corticosteroid therapies.
Estonian: Kaaluda tuleb täiendava glükokortikosteroidravi kasutamist.
English: Well-Controlled asthma was achieved more rapidly with Viani than with ICS alone.
Estonian: Hea kontroll astma üle saavutati kiiremini VIANI kui ainult inhaleeritava kortikosteroidi kasutamisel.
English: Viani is supplied to you in a metered dose inhaler which delivers your medicine in a pressurised suspension for you to inhale.
Estonian: Viani on aerosoolinhalaator, mis väljastab ravimit inhaleeritava aerosoolina, mida te sisse hingate.
English: Patients should breathe out as far as is comfortable and then place the mouthpiece in your mouth between their teeth and close their lips around it, Patients should be instructed not to bite the mouth piece.
Estonian: Patsiendid peavad sügavalt välja hingama ning seejärel huuliku suhu viima ja sulgema huuled selle ümber.
English: Fluticasone propionate given by inhalation at recommended doses has a glucocorticoid antiinflammatory action within the lungs, resulting in reduced symptoms and exacerbations of asthma, with less adverse effects than when corticosteroids are administered systemically.
Estonian: Flutikasoonpropionaat: inhaleeritav flutikasoonpropionaat avaldab terapeutilistes annustes glükokortikosteroididele iseloomulikku põletikuvastast toimet kopsudesse, vähendades astmasümptomeid ja ägenemisi, omamata süsteemsele manustamisele iseloomulikke kõrvaltoimeid.
English: Salmeterol xinafoate and fluticasone propionate
Estonian: Salmeterolum, fluticasonum
English: The container should not be punctured, broken or burnt even when apparently empty.
Estonian: Ballooni ei tohi avada, lõhkuda ega põletada ka juhul, kui see on tühi.
English: The pressurised can contains a white to off white suspension for inhalation.
Estonian: Survestatud mahuti sisaldab valkjat suspensiooni sissehingamiseks.
English: Adverse events which have been associated with salmeterol/fluticasone propionate are given below, listed by system organ class and frequency.
Estonian: Kõrvaltoimed on loetletud organsüsteemi klasside ja esinemissageduse järgi.
English: The containers are fitted into plastic actuators incorporating an atomising mouthpiece and fitted with dustcaps.
Estonian: Konteiner on plastmassist inhalaatoris, mis on varustatud pihustiga huuliku ja kattekorgiga.
English: Pressurised container.
Estonian: Metallmahuti on survestatud.
English: LIST OF EXCIPIENTS Norflurane (HFA 134a)
Estonian: Norfluraan (HFA 134a)
English: Pharmacotherapeutic Group: Adrenergics and other anti-asthmatics.
Estonian: Farmakoterapeutiline grupp: Adrenergilised ja teised astmavastased ained, ATC-kood: R03AK82
English: Viani Evohaler should not be used to treat acute asthma symptoms for which a fast and short acting bronchodilator is required.
Estonian: VIANI ei ole ette nähtud kasutamiseks ägedate haigusnähtude korral, mille leevendamiseks vajab patsient kiire- ja lühitoimelist inhaleeritavat bronhodilataatorit.
English: To clean your inhaler:
Estonian: Inhalaatori puhastamiseks:
English: Use of the inhaler:
Estonian: Inhalaatori kasutamine:
English: The medicine is contained in a pressurised can in a plastic casing with a mouthpiece.
Estonian: Ravim on rõhu all olevas mahutis, mida ümbritsev plastmasskorpus on varustatud huulikuga.
English: The canister contains a white to off white suspension.
Estonian: Konteineris on valge või tuhmvalge suspensioon.
English: There are no data available for use of Viani in patients with hepatic impairment.
Estonian: Puuduvad andmed VIANI kasutamise kohta maksapuudulikkuse korral.
English: Inhalation use
Estonian: Inhalaatori kasutamine
English: The management of asthma should normally follow a stepwise programme and patient response should be monitored clinically and by lung function tests.
Estonian: Hingamisteede pöörduva obstruktiivse haiguse ravis peab tavaliselt kasutama järk-järgulist raviskeemi ning ravimi toimet tuleb jälgida, arvestades haiguse kliinilist pilti ja kopsufunktsiooni näitajaid.
English: It is important, therefore, that the patient is reviewed regularly and the dose of inhaled corticosteroid is reduced to the lowest dose at which effective control of asthma is maintained.
Estonian: Seetõttu on oluline patsiendi regulaarne jälgimine ning hingamisteede pöörduva obstruktiivse haiguse korral inhaleeritava glükokortikoidi annuse tiitrimine madalaima efektiivse annuseni.
English: - Remove the mouthpiece cover.
Estonian: - Eemaldage huuliku kate.
English: Pooled results across the 3 treatment levels *Well controlled asthma; occasional symptoms or SABA use or less than 80% predicted lung function plus no night-time awakenings, no exacerbations and no side effects enforcing a change in therapy **Total control of asthma; no symptoms, no SABA use, greater than or equal to 80% predicted lung function, no night-time awakenings, no exacerbations and no side effects enforcing a change in therapy.
Estonian: *Hea kontroll: haigusnähtude esinemine või lühitoimeliste β-adrenomimeetikumide (SABA) kasutamine aeg-ajalt või kopsufunktsioon <80% normist pluss öiste ärkamiste, ägenemiste ja kõrvaltoimete, mis vajaksid ravi muutmist, puudumine.
English: In patients with asthma a lesser degree of systemic exposure to inhaled fluticasone propionate has been observed.
Estonian: Hingamisteede pöörduva obstruktiivse haigusega patsientidel on täheldatud väiksemat süsteemset toimet.
English: The devices are packed in cartons of 1, 3 or 10 Evohalers.
Estonian: Pakendi suurused: Viani Evohaler aerosoolinhalaator - 1, 3 või 10 tk pakendis.
English: - Wipe the inside and outside of the mouthpiece and the plastic casing with a dry cloth or tissue.
Estonian: - Pühkige kuiva lapi või pabersalvrätikuga üle huuliku sise- ja välispind ning plastmasskorpus.
English: WHAT VIANI IS AND WHAT IT IS USED FOR
Estonian: MIS RAVIM ON VIANI EVOHALER JA MILLEKS SEDA KASUTATAKSE
English: In these cases, the recommended initial dose is two inhalations of 25 micrograms salmeterol and 50 micrograms fluticasone propionate twice daily.
Estonian: Sellistel juhtudel on soovitatavaks algannuseks kaks inhalatsiooni 25 mikrogrammi salmeterooli ja 50 mikrogrammi flutikasoonpropionaati kaks korda päevas.