FrancophonIA/ELRC3.0 huggingface dataset:
English: In children whose mothers took NRTIs during pregnancy, the benefit from the protection against HIV outweighed the risk of side effects.
Croatian: U djece čije su majke tijekom trudnoće uzimale NRTI-jeve prevagnula je korist od zaštite protiv HIV-a u odnosu na rizike od nuspojava.
English: renal failure (acute and chronic), acute tubular necrosis, nephritis (including acute interstitial nephritis)3, nephrogenic diabetes insipidus
Croatian: zatajenje bubrega (akutno i kronično), akutna tubularna nekroza, nefritis (uključujući akutni intersticijski nefritis)3, nefrogeni dijabetes insipidus
English: Also, emtricitabine did not inhibit uridine-5'-diphosphoglucuronyl transferase, the enzyme responsible for glucuronidation.
Croatian: Također, emtricitabin nije inhibirao uridin-5'-difosfoglukuronil transferazu, enzim koji je odgovoran za glukuronidaciju.
English: Some examples include, but are not limited to, aminoglycosides, amphotericin B, foscarnet, ganciclovir, pentamidine, vancomycin, cidofovir or interleukin-2 (see section 4.4).
Croatian: Neki primjeri uključuju, ali nisu ograničeni na aminoglikozide, amfotericin B, foskarnet, ganciklovir, pentamidin, vankomicin, cidofovir ili interleukin-2 (vidjeti dio 4.4).
English: Late onset neurological disorders have been reported rarely (hypertonia, convulsion, abnormal behaviour).
Croatian: Rijetko su zabilježeni neurološki poremećaji s kasnim nastupom (hipertonija, konvulzija, abnormalno ponašanje).
English: Summary of the safety profile
Croatian: Sažetak profila sigurnosti primjene
English: Eight of the 89 patients (9.0%) discontinued study drug due to renal adverse events.
Croatian: Osam od 89 pacijenata (9,0%) prekinulo je uzimanje ispitivanog lijeka zbog štetnih događaja povezanih s bubrezima.
English: Methadone:
Croatian: Metadon:
English: rhabdomyolysis1, muscular weakness1
Croatian: rabdomioliza1, mišićna slabost1
English: • If you become pregnant, or plan to become pregnant, ask your doctor about the potential benefits and risks of therapy with emtricitabine/Tenofovir disoproxil to you and your child.
Croatian: • Ako ostanete trudni ili planirate trudnoću, posavjetujte se s liječnikom o potencijalnim koristima i rizicima liječenja emtricitabin/tenofovirdizoproksilom po Vas i dijete.
English: Damage to kidney tubule cells may be associated with breakdown of muscle, softening of the bones (with bone pain and sometimes resulting in fractures), muscle pain, muscle weakness and decreases in potassium or phosphate in the blood.
Croatian: Oštećenje stanica bubrežnih kanalića može biti povezano s razgradnjom mišića, omekšavanjem kosti (uz bol u kostima i ponekad posljedičnim prijelomima), bolom u mišićima, mišićnom slabošću i sniženjem razine kalija ili fosfata u krvi.
English: • increased triglycerides (fatty acids), bile or sugar in the blood
Croatian: • povišene trigliceride (masne kiseline), bilirubin (žučna boja) ili šećer u krvi
English: The potential risks and benefits associated with co-administration should be considered, particularly in patients at increased risk of renal dysfunction.
Croatian: Potrebno je razmotriti moguće rizike i koristi povezane s istovremenom primjenom, osobito u pacijenata s povećanim rizikom od poremećaja funkcije bubrega.
English: ** The p-value based on the Cochran-Mantel-Haenszel Test stratified for baseline CD4 cell count TLOVR = Time to Loss of Virologic
Croatian: ** p-vrijednost se temeljila na Cochran-Mantel-Haenszelovu testu uslojenom prema početnom broju CD4 stanica TLOVR = vrijeme do gubitka virološkog odgovora (engl.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to CART.
Croatian: Iako se smatra da je etiologija multifaktorska (uključujući primjenu kortikosteroida, konzumaciju alkohola, tešku imunosupresiju, veći indeks tjelesne mase), zabilježeni su slučajevi osteonekroze osobito u pacijenata s uznapredovalom HIV-bolešću i/ili dugotrajnom izloženošću CART-u.
English: The main adverse reactions reported are haematological disorders (anaemia, neutropenia) and metabolic disorders (hyperlactatemia, hyperlipasemia).
Croatian: Glavne zabilježene nuspojave su hematološki poremećaji (anemija, neutropenija) i metabolički poremećaji (hiperlaktatemija, hiperlipazemija).
English: 2 The predominant circulating metabolite of sofosbuvir.
Croatian: 2 Glavni metabolit sofosbuvira u cirkulaciji.
English: Patients with hepatitis B or C virus infection
Croatian: Pacijenti s infekcijom virusom hepatitisa B ili C
English: Tenofovir is primarily excreted by the kidney by both filtration and an active tubular transport system with approximately 70-80% of the dose excreted unchanged in urine following intravenous administration.
Croatian: Tenofovir se prvenstveno izlučuje preko bubrega filtracijom i aktivnim tubularnim transportnim sustavom, pri čemu se oko 70-80% doze izlučuje u nepromijenjenom obliku u mokraći nakon intravenske primjene.
English: SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS OR
Croatian: 10. POSEBNE MJERE ZA ZBRINJAVANJE NEISKORIŠTENOG LIJEKA ILI
English: McDermott Laboratories Limited T/A Gerard Laboratories T/A Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited T/A Gerard Laboratories T/A Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Irska
English: Maximum emtricitabine and tenofovir concentrations are observed in serum within 0.5 to 3.0 h of dosing in the fasted state.
Croatian: Maksimalne koncentracije emtricitabina i tenofovira zapažaju se u serumu unutar 0,5 do 3,0 h od doziranja natašte.
English: Medis International a.s vyrobani zavod Bolatice,Prumyslova, -961/16, Bolatice 747 23, Czech Republic
Croatian: Medis International a.s vyrobani zavod Bolatice, Prumyslova, -961/16, Bolatice 747 23, Češka Republika
English: • Talk to your doctor if you are over 65.
Croatian: • Ako ste stariji od 65 godina, razgovarajte s liječnikom.
English: 4.1 Therapeutic indications
Croatian: 4. KLINIČKI PODACI 4.1 Terapijske indikacije
English: Osteonecrosis: Cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to CART.
Croatian: Osteonekroza: Zabilježeni su slučajevi osteonekroze, osobito u pacijenata s općepoznatim čimbenicima rizika, uznapredovalom HIV bolešću ili dugotrajnom izloženošću CART-u.
English: The difference in the proportion of patients who maintained < 400 copies/mL at week 48 was mainly influenced by the higher number of discontinuations in the tenofovir disoproxil treatment group.
Croatian: Razlika u udjelu pacijenata koji su održali < 400 kopija/ml u 48. tjednu uglavnom je posljedica većeg broja odustajanja u skupini koja je dobivala tenofovirdizoproksil.
English: The biotransformation of emtricitabine includes oxidation of the thiol moiety to form the 3'-sulphoxide diastereomers (approximately 9% of dose) and conjugation with glucuronic acid to form 2'-O-glucuronide (approximately 4% of dose).
Croatian: Biotransformacija emtricitabina uključuje oksidaciju tiolnog dijela molekule pri čemu nastaju 3'-sulfoksid diastereomeri (oko 9% doze), i konjugaciju s glukuronskom kiselinom, pri čemu nastaje 2'-O-glukuronid (oko 4% doze).
English: Thirteen percent of the emtricitabine dose was recovered in urine as three metabolites.
Croatian: Trinaest posto doze emtricitabina izolirano je u mokraći kao tri metabolita.
English: A large amount of data on pregnant women (more than 1,000 pregnancy outcomes) indicate no malformations or foetal/neonatal toxicity associated with emtricitabine and tenofovir disoproxil.
Croatian: Opsežni podaci u trudnica (više od 1000 trudnoća) ne ukazuju na malformacije ili fetalnu/neonatalnu toksičnost povezanu s emtricitabinom i tenofovirdizoproksilom.
English: If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Croatian: Ako u tih pacijenata nastupe znakovi pogoršanja bolesti jetre, mora se razmisliti o privremenom ili trajnom prekidu liječenja.
English: In infants and children older than 4 months, the majority of patients taking emtricitabine achieved or maintained complete suppression of plasma HIV 1 RNA through 48 weeks (89% achieved ≤ 400 copies/mL and 77% achieved ≤ 50 copies/mL).
Croatian: U dojenčadi i djece starije od 4 mjeseca, većina pacijenata koji su primali emtricitabin postigla je ili održala potpunu supresiju plazmatske HIV-1 RNK tijekom 48 tjedana (89% postiglo je ≤ 400 kopija/ml, a 77% postiglo je ≤ 50 kopija/ml).
English: Mylan Hungary Kft Mylan utca 1, H-2900 Komárom, Hungary
Croatian: Mylan Hungary Kft Mylan utca 1, H-2900 Komárom, Mađarska
English: • deep rapid breathing
Croatian: • duboko, ubrzano disanje
English: If bone abnormalities are suspected then appropriate consultation should be obtained.
Croatian: U slučaju sumnje na abnormalnosti kosti, potrebno je odgovarajuće se konzultirati.
English: However, there was no increased risk of fractures or evidence for clinically relevant bone abnormalities over 144 weeks.
Croatian: Međutim, tijekom 144 tjedna nije bilo povećanog rizika od prijeloma ili znakova klinički važnih abnormalnosti kosti.
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jirovecii pneumonia.
Croatian: Relevantni primjeri su citomegalovirusni retinitis, generalizirane i/ili žarišne mikobakterijske infekcije, te upala pluća uzrokovana s Pneumocystis jirovecii.
English: The most frequent adverse reaction reported in the emtricitabine/tenofovir disoproxil group in the iPrEx study was headache (1%).
Croatian: Najčešća nuspojava prijavljena u skupini koja je primala emtricitabin/tenofovirdizoproksil u ispitivanju iPrEx bila je glavobolja (1 %).
English: If you feel dizzy while taking this medicine, do not drive and do not use any tools or machines.
Croatian: Ako tijekom uzimanja ovoga lijeka imate omaglicu, nemojte upravljati vozilom niti raditi s alatima ili strojevima.
English: Following oral administration, the elimination half-life of emtricitabine is approximately 10 hours.
Croatian: Nakon peroralne primjene, poluvrijeme eliminacije emtricitabina je oko 10 sati.
English: In other studies (prospective and cross-sectional), the most pronounced decreases in BMD were seen in patients treated with tenofovir disoproxil as part of a regimen containing a boosted protease inhibitor.
Croatian: U drugim ispitivanjima (prospektivnim i presječnim), najizraženija smanjenja BMD-a bila su opažena u pacijenata liječenih tenofovirdizoproksilom u sklopu režima koji je sadržavao pojačan inhibitor proteaze.
English: Emtricitabine/tenofovir disoproxil should only be used in individuals with creatinine clearance (CrCl) <80 mL/min if the potential benefits are considered to outweigh the potential risks.
Croatian: Emtricitabin/tenofovirdizoproksil se smije koristiti samo u osoba s klirensom kreatinina (CrCl) < 80 ml/min ako se smatra da su moguće koristi veće od mogućih rizika.
English: • non-steroidal anti-inflammatory drugs (NSAIDs, to relieve bone or muscle pains)
Croatian: • nesteroidne antiinflamatorne (protuupalne) lijekove (NSAIL, za ublažavanje boli u kostima ili mišićima)
English: Tenofovir disoproxil: Non-clinical safety pharmacology studies on tenofovir disoproxil reveal no special hazard for humans.
Croatian: Tenofovirdizoproksil: Neklinička ispitivanja sigurnosne farmakologije tenofovirdizoproksila ne ukazuju na poseban rizik za ljude.
English: This is because the active substances in this medicine pass into human breast milk.
Croatian: Djelatne tvari iz ovoga lijeka prelaze u majčino mlijeko.
English: If you have difficulty swallowing, you can use the tip of a spoon to crush the tablet.
Croatian: Ako teško gutate, tabletu možete smrviti vrhom žlice.
English: If you are taking another antiviral medicine called a protease inhibitor to treat HIV, your doctor may order blood tests to closely monitor your kidney function.
Croatian: Ako uzimate druge antivirusne lijekove koji se nazivaju inhibitori proteaze za liječenje HIV-a, Vaš liječnik može naručiti pretrage krvi kako bi pažljivo nadzirao Vašu funkciju bubrega.
English: Oral carcinogenicity studies in rats and mice only revealed a low incidence of duodenal tumours at an extremely high dose in mice.
Croatian: Ispitivanja kancerogenosti peroralne primjene u štakora i miševa pokazala su tek nisku incidenciju duodenalnih tumora, pri izuzetno visokoj dozi kod miševa.
English: Physicians should refer to current HIV treatment guidelines for the management of HIV infection in patients co-infected with hepatitis B virus (HBV) or hepatitis C virus (HCV).
Croatian: Liječnici se trebaju pridržavati trenutno važećih smjernica za liječenje infekcije HIV-om u pacijenata istovremeno zaraženih virusom hepatitisa B (HBV) ili virusom hepatitisa C (HCV).
English: 30 film-coated tablets
Croatian: 30 filmom obloženih tableta.
English: • Emtricitabine/Tenofovir disoproxil Mylan is also used to reduce the risk of getting HIV-1 infection in adults, and adolescents aged 12 years to less than 18 years who weigh at least 35 kg, when used as a daily treatment, together with safer sex practices:
Croatian: • Emtricitabin/tenofovirdizoproksil Mylan se također primjenjuje za smanjenje rizika od dobivanja infekcije virusom HIV-1 u odraslih i adolescenata u dobi od 12 do navršenih 18 godina koji imaju najmanje 35 kg, kad se primjenjuje kao svakodnevno liječenje zajedno s provođenjem mjera sigurnijih spolnih odnosa:
English: • If you have hepatitis B, it is especially important not to stop your treatment with Emtricitabine/Tenofovir disoproxil Mylan without talking to your doctor first.
Croatian: • Ako imate i hepatitis B, naročito je važno da se ne prestanete liječiti lijekom Emtricitabin/tenofovirdizoproksil Mylan, a da prije toga niste razgovarali s liječnikom.
English: If you have any further questions, ask your doctor or pharmacist.
Croatian: Ako imate dodatnih pitanja, obratite se liječniku ili ljekarniku.
English: Due to limitations of the study, a benefit of tenofovir disoproxil over placebo was not demonstrated based on plasma HIV 1 RNA levels at week 24.
Croatian: Zbog ograničenja ispitivanja, korist od tenofovirdizoproksila u usporedbi s placebom nije dokazana temeljem razina plazmatske HIV-1 RNK u 24. tjednu.
English: • joint aches and pains (especially of the hip, knee and shoulder)
Croatian: • bol u zglobovima (osobito u kuku, koljenu i ramenu)
English: If you have HBV, there is a serious risk of liver problems when you stop taking emtricitabine/tenofovir disoproxil, whether or not you also have HIV.
Croatian: Ako imate HBV, postoji ozbiljan rizik od tegoba s jetrom kada prestanete uzimati emtricitabin/tenofovirdizoproksil, bez obzira na to imate li i HIV.
English: EU/1/16/1133/001 EU/1/16/1133/002 EU/1/16/1133/003 EU/1/16/1133/004 EU/1/16/1133/005 EU/1/16/1133/006
Croatian: EU/1/16/1133/001 EU/1/16/1133/003 EU/1/16/1133/004 EU/1/16/1133/005 EU/1/16/1133/006
English: elevated creatine kinase
Croatian: povišena kreatin kinaza
English: Patients infected with HBV who discontinue emtricitabine/tenofovir disoproxil therapy should be closely monitored with both clinical and laboratory follow-up for at least several months after stopping treatment.
Croatian: Pacijente zaražene HBV-om koji prestanu uzimati emtricitabin/tenofovirdizoproksil treba pažljivo pratiti uz kliničku i laboratorijsku kontrolu tijekom najmanje nekoliko mjeseci nakon prestanka liječenja.
English: The primary efficacy endpoint for this study was the achievement and maintenance of confirmed HIV-1 RNA concentrations < 400 copies/mL over 48 weeks.
Croatian: Primarna mjera ishoda djelotvornosti u ovom ispitivanju bila je postizanje i održavanje potvrđene HIV-1 RNK koncentracije < 400 kopija/ml tijekom 48 tjedana.
English: In vitro studies have determined that neither tenofovir disoproxil nor tenofovir are substrates for the CYP450 enzymes.
Croatian: In vitro ispitivanja pokazala su da ni tenofovirdizoproksil ni tenofovir nisu supstrati za CYP450 enzime.
English: Medis International a.s Bolatice, Prumyslova 961/16, 747 23 Bolatice, Czech Republic
Croatian: Medis International a.s Bolatice, Prumyslova 961/16, 747 23 Bolatice, Češka Republika
English: In clinical studies of HIV-1 uninfected individuals, small decreases in BMD were observed.
Croatian: U kliničkim ispitivanjima u osoba koje nisu zaražene virusom HIV-1 bila su opažena mala smanjenja BMD-a.
English:  If you notice any of the side effects listed above or if any of the side effects get serious, talk to your doctor or pharmacist.
Croatian: Ako primijetite bilo koju od gore navedenih nuspojava ili ako neka nuspojava postane ozbiljna, obratite se svom liječniku ili ljekarniku.
English: In general, emtricitabine pharmacokinetics in HBV infected subjects were similar to those in healthy subjects and in HIV infected patients.
Croatian: Općenito je farmakokinetika emtricitabina u osoba zaraženih virusom HBV-a bila slična farmakokinetici u zdravih ispitanika i u HIV-om zaraženih pacijenata.
English: The bone toxicity in young adult rats and dogs occurred at exposures ≥ 5-fold the exposure in paediatric or adult patients; bone toxicity occurred in juvenile infected monkeys at very high exposures following subcutaneous dosing (≥ 40-fold the exposure in patients).
Croatian: U mladih odraslih štakora i pasa toksičnost za kosti pokazala se pri izloženosti dozi za ≥ 5 puta većoj od izloženosti kod pedijatrijskih ili odraslih pacijenata; toksičnost za kosti pojavila se u mladih zaraženih majmuna pri vrlo visokim izloženostima nakon supkutanog doziranja (za ≥ 40 puta veća izloženost nego u pacijenata).
English: This medicine should not be given to adolescents with existing kidney problems.
Croatian: Ovaj se lijek ne smije propisati adolescentima koji imaju tegobe s bubrezima.
English: In vitro protein binding of tenofovir to plasma or serum protein was less than 0.7 and 7.2%, respectively, over the tenofovir concentration range 0.01 to 25 μg/mL.
Croatian: In vitro proteinsko vezanje tenofovira na proteine plazme ili seruma bilo je manje od 0,7 odnosno 7,2%, u rasponu koncentracija tenofovira od 0,01 do 25 µg/ml.
English: If you have taken Emtricitabine/Tenofovir disoproxil Mylan during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Croatian: Ako ste lijek Emtricitabin/tenofovirdizoproksil Mylan uzimali tijekom trudnoće, postoji mogućnost da liječnik zatraži redovito provođenje pretraga krvi i drugih dijagnostičkih pretraga kako bi pratio razvoj Vašega djeteta.
English: Emtricitabine/tenofovir disoproxil is not always effective in preventing the acquisition of HIV-1.
Croatian: Emtricitabin/tenofovirdizoproksil nije uvijek djelotvoran u sprječavanju dobivanja virusa HIV-1.
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infections (infections that occur in people with a weak immune system), signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Croatian: U nekih pacijenata s uznapredovalom infekcijom virusa HIV-a (SIDA) i oportunističkim infekcijama u povijesti bolesti (infekcije koje nastaju u osoba sa slabim imunloškim sustavom) mogu se pojaviti znakovi i simptomi upale od prethodnih infekcija ubrzo nakon početka liječenja lijekovima protiv HIV-a.
English: The incidences of HIV seroconversion overall and in the subset reporting unprotected receptive anal intercourse are shown in Table 6.
Croatian: Incidencija serokonverzije HIV-a u svih ispitanika i u podskupini koja je prijavila nezaštićeni receptivni analni spolni odnos prikazani su u Tablici 6.
English: • That Emtricitabine/Tenofovir disoproxil Mylan may cause a reduction in BMD and the effects of Emtricitabine/Tenofovir disoproxil Mylan associated changes in BMD on long term bone health and future fracture risk are currently unknown in paediatric patients
Croatian: • Emtricitabin/tenofovirdizoproksil Mylan može izazvati smanjenje BMD-a, a učinci promjena BMD-a povezanih s lijekom Emtricitabin/tenofovirdizoproksil Mylan na dugoročno zdravlje kosti i rizik od budućih lomova u pedijatrijskih pacijenata trenutno nisu poznati.
English: b Substudy participants received active adherence monitoring, e.g. unannounced home visits and pill counts, and counselling to improve compliance with study drug.
Croatian: b U ispitanika u podispitivanju aktivno je praćeno pridržavanje terapije, npr. putem nenajavljenih kućnih posjeta i brojenja tableta, i savjetovanja radi poboljšanja suradljivosti u uzimanju ispitivanog lijeka.
English: Patients should be advised to seek medical advice if they experience joint aches and pain, joint stiffness or difficulty in movement.
Croatian: Pacijente treba uputiti da se obrate liječniku ako osjete bolove u zglobovima, ukočenost zglobova ili poteškoće pri kretanju.
English: Individuals over the age of 65 years are more likely to have decreased renal function, therefore caution should be exercised when administering emtricitabine/tenofovir disoproxil to older people.
Croatian: Kod osoba starijih od 65 godina veća je vjerojatnost da imaju smanjenu funkciju bubrega, pa je stoga potrebno primijeniti oprez kad se emtricitabin/tenofovirdizoproksil primjenjuje kod starijih osoba.
English: Before and during treatment, your doctor may order blood tests to measure kidney function.
Croatian: Prije početka i tijekom liječenja liječnik će možda zatražiti krvne pretrage kako bi se izmjerila funkcija bubrega.
English: There is limited metabolism of emtricitabine.
Croatian: Metabolizam emtricitabina je ograničen.
English: McDermott Laboratories Limited trading as Gerard Laboratories trading as Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited koji posluje kao Gerard Laboratories koji posluje kao Mylan Dublin 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13
English: If clinical symptoms consistent with acute viral infection are present and recent (< 1 month) exposures to HIV-1 are suspected, use of emtricitabine/tenofovir disoproxil should be delayed for at least one month and HIV-1 status reconfirmed before starting emtricitabine/tenofovir disoproxil for pre-exposure prophylaxis.
Croatian: Ako su prisutni klinički simptomi sukladni akutnoj virusnoj infekciji, a sumnja se na nedavnu (< 1 mjeseca) izloženost virusu HIV-1, primjenu emtricitabin/tenofovirdizoproksila treba odgoditi za najmanje mjesec dana i ponovno provjeriti HIV-1 status prije početka primjene emtricitabin/tenofovirdizoproksila za predekspozicijsku profilaksu.
English: • If you are a woman with HIV it is recommended that you do not breast-feed, to avoid passing the virus to the baby in breast milk.
Croatian: • Ako ste žena zaražena virusom HIV-a, preporučuje se da ne dojite kako bi se izbjegla mogućnost da virus u majčinom mlijeku prijeđe na dojenče.
English: Up to 30% of the emtricitabine dose and approximately 10% of the tenofovir dose can be removed by haemodialysis.
Croatian: Hemodijalizom se može ukloniti do 30% doze emtricitabina i približno 10% doze tenofovira.
English: In vitro and clinical pharmacokinetic interaction studies have shown the potential for CYP450 mediated interactions involving emtricitabine and tenofovir disoproxil with other medicinal products is low.
Croatian: In vitro i klinička ispitivanja farmakokinetičkih interakcija pokazala su da je potencijal za interakcije posredstvom CYP450, koje uključuju emtricitabin i tenofovirdizoproksil s drugim lijekovima, nizak.
English: See also under Co-administration of other medicinal products below.
Croatian: Vidjeti također niže pod Istovremena primjena s drugim lijekovima.
English: Therefore, the same problems may be seen if emtricitabine/tenofovir disoproxil is administered with a third nucleoside analogue.
Croatian: Stoga se mogu uočavati isti problemi ako se emtricitabin/tenofovirdizoproksil daje s nekim trećim analogom nukleozida.