FrancophonIA/ELRC3.0 huggingface dataset:
English: The MTD of capecitabine alone using the intermittent regimen is 3,000 mg/m² per day, whereas, when combined with radiotherapy for rectal cancer, the MTD of capecitabine is 2,000 mg/m² per day using either a continuous schedule or given daily Monday through Friday during a 6-week course of radiotherapy.
Danish: MTD for capecitabin alene ved anvendelse af det intermitterende regime er 3.000 mg/m² pr. dag, hvorimod MTD er 2.000 mg/m² pr. dag, når capecitabin kombineres med stråleterapi ved kolorektalkræft, enten ved anvendelse af en kontinuerlig behandling eller anvendt dagligt fra mandag til fredag under en seks ugers-serie med stråleterapi.
English: If you are a male patient and your female partner could become pregnant, you should use effective contraception during treatment with Capecitabine medac and for 3 months after the last dose.
Danish: Hvis du er en mandlig patient og din kvindelige partner kan blive gravid, så skal du anvende sikker prævention under behandling med Capecitabine medac og i 3 måneder efter sidste dosis.
English: Table 5 Summary of related ADRs reported in patients treated with capecitabine in combination treatment in addition to those seen with capecitabine monotherapy or seen at a higher frequency grouping compared to capecitabine monotherapy Body system
Danish: Tabel 5 Sammenfatning af relaterede bivirkninger, som blev rapporteret hos patienter, der blev behandlet med capecitabin i kombinationsbehandling set ud over bivirkninger efter behandling med capecitabin-monoterapi eller set i en højere frekvensgruppe sammenlignet med capecitabin-monoterapi
English: Diarrhoea, Vomiting, Nausea, Stomatitis, Abdominal pain
Danish: Diarré, Opkastning, Kvalme, Stomatitis, Abdominalsmerter
English: • if you have imbalances of ions in your blood (electrolyte imbalances, seen in tests),
Danish: • hvis du har for få eller for mange ioner i blodet (elektrolytubalancer, der kan ses i blodprøver)
English: A clinically significant interaction between brivudine and fluoropyrimidines (e.g. capecitabine, 5-fluorouracil, tegafur), resulting from the inhibition of dihydropyrimidine dehydrogenase by brivudine, has been described.
Danish: Der er beskrevet en klinisk signifikant interaktion mellem brivudin og fluorpyrimidiner (f.eks. capecitabin, 5-FU, tegafur), som et resultat af brivudins hæmning af dihydropyrimidindehydrogenase.
English: The 3 year DFS rate was 71 % for XELOX versus 67 % for 5-FU/LV.
Danish: Raten for 3 års sygdomsfri overlevelse var 71 % for XELOX versus 67 % for 5-FU/LV.
English: In the case of colorectal tumours, 5-FU generation appears to be in large part localised in tumour stromal cells.
Danish: For så vidt angår kolorektale tumorer, synes dannelsen af 5-FU hovedsagelig at være lokaliseret til stromale tumorceller.
English: Leucovorin on Days 1 and 2, every 2 weeks 5-fluorouracil intravenous bolus/infusion, each on Days 1 and 2, every 2 weeks
Danish: 5-fluorouracil intravenøs bolus/infusion, hver på dag 1 og 2, hver 2. uge
English: NCIC CTC grade 2 diarrhoea is defined as an increase of 4 to 6 stools/day or nocturnal stools, grade 3 diarrhoea as an increase of 7 to 9 stools/day or incontinence and malabsorption.
Danish: NCIC CTC grad 2diarré defineres som en øgning til 4 til 6 afføringer/dag eller natlige afføringer, grad 3-diarré som en øgning til 7 til 9 afføringer/dag eller inkontinens og malabsorption og grad 4 diarré som en øgning til flere end 10 afføringer/dag eller stærkt blodig diarré eller behov for parenteral støttebehandling.
English: If you are a woman who could become pregnant you should use effective contraception during treatment with Capecitabine medac and for 6 months after the last dose.
Danish: Hvis du er en kvinde, der kan blive gravid, skal du anvende sikker prævention under behandling med Capecitabine medac og i 6 måneder efter sidste dosis.
English: For patients 60 years of age or more, a starting dose reduction of capecitabine to 75 % (950 mg/m² twice daily) is recommended.
Danish: Til patienter på 60 år og derover anbefales det at reducere initialdosis af capecitabin til 75 % af vanlig initialdosis (950 mg/m² to gange dagligt).
English: • decreases in the number of white blood cells or red blood cells (seen in tests)
Danish: • fald i antallet af hvide eller røde blodlegemer (måles i blodprøver)
English: Patients taking coumarin-derivative anticoagulants concomitantly with capecitabine should be monitored regularly for alterations in their coagulation parameters (PT or INR) and the anticoagulant dose adjusted accordingly.
Danish: Patienter, som tager antikoagulantia af coumarintypen sammen med capecitabin, skal kontrolleres regelmæssigt mht. ændringer i deres koagulationsparametre (PT eller INR), og antikoagulansdosis skal om nødvendigt justeres.
English: • decreases in blood cells including platelets, thinning of blood (seen in tests)
Danish: • fald i antallet af blodceller, herunder blodplader, fortyndet blod (målt i blodprøver)
English: SPECIAL STORAGE CONDITIONS For PVC/PVdC/Aluminium blisters: Do not store above 30 °C
Danish: PVC/PVdC/aluminium-blistere: Må ikke opbevares ved temperaturer over 30 °C.
English: For the capecitabine dose of 1,000 mg/m² twice daily on days 1 to 14 every 3 weeks, a frequency of 22 % to 30 % of all-grade HFS was observed in capecitabine combination therapy.
Danish: For en capecitabindosis på 1.000 mg/m² to gange daglig på dagene 1 til 14 hver 3. uge blev der observeret HFS i alle grader med en hyppighed på 22 % til 30 % i capecitabin-kombinationsbehandling.
English: Pharyngolaryngeal pain, Dysphonia
Danish: Hikke, Faryngolaryngeal smerte, Dysfoni
English: In patients with moderate renal impairment at baseline, no dose reduction is required for a starting dose of 1,000 mg/m².
Danish: Til patienter med moderat nyreinsufficiens ved baseline er det for en initialdosis på 1.000 mg/m² ikke nødvendigt med dosisjustering.
English: Capecitabine medac is not indicated in children and adolescents.
Danish: Capecitabine medac er ikke beregnet til børn eller unge.
English: Hand--foot syndrome
Danish: Hånd- og fodsyndrom
English: Dose limiting toxicities include diarrhoea, abdominal pain, nausea, stomatitis and hand-foot syndrome (HFS, hand-foot skin reaction, palmar-plantar erythrodysesthesia).
Danish: Dosisbegrænsende toksicitet omfatter diarré, mavesmerter, kvalme, stomatitis og hånd- og fodsyndrom (HFS, hånd og fod hudreaktioner, palmo-plantar erytrodysæstesi).
English: • Hand-and-foot skin-reaction: if you have pain, swelling, redness or tingling of hands and/or feet.
Danish: • Hånd- og fod symptomer: hvis du har smerter, hævelse, rødme eller prikken i hænder og/eller fødder.
English: Grade 2 HFS is painful erythema and swelling of the hands and/or feet and/or discomfort affecting the patient's activities of daily living.
Danish: Grad 2 HFS defineres som smertefuld erytem og hævelse af hænderne og/eller fødderne og/eller ubehag, der påvirker patienternes daglige aktiviteter.
English: XELOX showed a trend towards superior OS with a HR of 0.87 (95 % CI = [0.72; 1.05]; p = 0.1486) which translates into a 13 % reduction in risk of death.
Danish: XELOX viste en tendens til en bedre samlet overlevelse med en hazard ratio på 0,87 (95 % konfidensinterval = [0,72; 1,05], p = 0,1486), hvilket svarer til en reduktion i risikoen for dødsfald på 13 %.
English: Median OS was 23.1 months for FOLFIRI, 17.6 months for mIFL (p = 0.09), and 18.9 months for XELIRI (p = 0.27).
Danish: Den mediane samlede overlevelse var 23,1 måneder for FOLFIRI, 17,6 måneder for mIFL (p = 0,09) og 18,9 måneder for XELIRI (p = 0,27).
English: • diabetes, decrease in blood potassium, malnutrition, increased blood triglycerides
Danish: • sukkersyge, fald i mængden af kalium i blodet, fejlernæring, øget mængde triglycerider i blodet
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON FOR BLISTER
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE YDRE KARTON
English: • if you have diabetes,
Danish: • hvis du har sukkersyge
English: For combination with irinotecan, the recommended starting dose is 800 mg/m² when administered twice daily for 14 days followed by a 7-day rest period combined with irinotecan 200 mg/m² on day 1.
Danish: Ved kombination med irinotecan er den anbefalede initialdosis 800 mg/m², når det administreres to gange dagligt i 14 dage efterfulgt af en pause på 7 dage kombineret med irinotecan 200 mg/m² på dag 1.
English: The incidence of grade 3 or 4 adverse reactions in patients with moderate renal impairment (creatinine clearance 30 - 50 ml/min at baseline) is increased compared to the overall population.
Danish: Incidensen af bivirkninger af sværhedsgrad 3 eller 4 er højere hos patienter med moderat nyreinsufficiens (creatininclearance 30 - 50 ml/min ved baseline) sammenlignet med den samlede population.
English: Pre-medication with an oral corticosteroid such as dexamethasone according to the docetaxel summary of product characteristics should be started prior to docetaxel administration for patients receiving the capecitabine plus docetaxel combination.
Danish: Præmedicinering med et oralt kortikosteroid, som f.eks. dexamethason, af patienter, som får en kombination af capecitabin og docetaxel, bør ifølge produktresumeet for docetaxel påbegyndes, før der gives docetaxel.
English: In a randomised, controlled phase III study (CAIRO), the effect of using capecitabine at a starting dose of 1,000 mg/m² for 2 weeks every 3 weeks in combination with irinotecan for the first-line treatment of patients with metastatic colorectal cancer was studied.
Danish: I et randomiseret, kontrolleret fase III-studie (CAIRO) blev effekten af capecitabin ved anvendelse af en initial dosis på 1.000 mg/m² i 2 uger hver 3. uge i kombination med irinotecan som 1. linjebehandling af patienter med metastatisk kolorektalkræft undersøgt.
English: • if you have severe liver or kidney problems,
Danish: • hvis du har alvorlige leversygdomme eller problemer med nyrerne
English: • blood infection, urinary tract infection, infection of the skin, infections in the nose and throat,
Danish: • blodinfektion, urinvejsinfektion, hudinfektion, infektioner i næse eller hals, svampeinfektioner
English: Hypersensitivity reaction, Hypoaesthesia
Danish: Overfølsomhedreaktioner, Hypoæstesi
English: • if you know that you have a partial deficiency in the activity of the enzyme dihydropyrimidine dehydrogenase (DPD),
Danish: • hvis du ved, at du har delvis mangel på aktivitet af enzymet dihydropyrimidindehydrogenase
English: The hazard ratio for duration of survival (overall survival) was similar to the hazard ratio for PFS (hazard ratio 0.85; 95 % CI 0.64 - 1.13).
Danish: Resultatet for hazard ratio for varighed af overlevelse (samlet overlevelse) svarede til resultatet for hazard ratio for PFS (hazard ratio 0,85, 95 % konfidensinterval 0,64 - 1,13).
English: • for the adjuvant treatment of patients following surgery of stage III (Dukes' stage C) colon cancer (see section 5.1).
Danish: • for den adjuverende behandling af patienter, som er opereret for stadium III (Dukes stadium C)
English: Capecitabine medac is indicated:
Danish: Capecitabine medac indeholder:
English: Capecitabine in combination with cisplatin was non-inferior to 5-FU in combination with cisplatin in terms of PFS in the per protocol analysis (hazard ratio 0.81; 95 % CI 0.63 - 1.04).
Danish: Capecitabin var i kombination med cisplatin non-inferiørt i forhold til 5-FU i kombination med cisplatin med hensyn til PFS i per protokolanalysen (hazard ratio 0,81; 95 % konfidensinterval 0,63 - 1,04).
English: Patients receiving concomitant capecitabine and oral coumarin-derivative anticoagulant therapy should have their anticoagulant response (International Normalised Ratio [INR] or prothrombin time) monitored closely and the anticoagulant dose adjusted accordingly (see section 4.5).
Danish: Hos patienter, som samtidig får behandling med capecitabin og orale antikoagulantia af coumarintypen, skal antikoagulansresponset (international normaliseret ratio [INR] eller protrombintiden) monitoreres tæt, og antikoagulansdosis justeres, om nødvendigt (se pkt.
English: Mucosal inflammation, Pain in limb, Pain, Chills, Chest pain, Influenza-like illness, +Fever, Infusion-related reaction, Injection site reaction, Infusion site pain, Injection site pain
Danish: Mukosal inflammation, Smerter i ekstremiteterne, Smerter, Kuldegysninger, Brystsmerter, Influenzalignende symptomer, +Feber, Infusionsrelateret reaktion, Reaktion på injektionsstedet, Smerter på infusionsstedet, Smerter på injektionsstedet
English: Angina unstable, Angina pectoris, Myocardial ischaemia, Atrial fibrillation, Arrhythmia, Tachycardia, Sinus tachycardia, Palpitations
Danish: Ustabil angina, Angina pectoris, Myokardiel iskæmi, Atrieflimmer, Arytmi,
English: In case you are using coumarin anticoagulants (containing e.g. phenprocoumon), stopping capecitabine might require that your doctor adjusts your anticoagulant dose.
Danish: Hvis du bruger blodfortyndende medicin (antikoagulantia) af coumarintypen (f.eks. phenprocoumon), kan det blive nødvendigt, at din læge ændrer dosis af denne medicin, hvis behandlingen med capecitabin stopper.
English: • Stomatitis: if you have pain, redness, swelling or sores in your mouth and or throat.
Danish: • Mundbetændelse: hvis du har smerter, rødme, hævelse eller sår i din mund og/eller hals.
English: Tablet core: anhydrous lactose, croscarmellose sodium (E468), hypromellose (E464), microcrystalline cellulose (E460), magnesium stearate (E572) - see section 2 “Capecitabine medac contains lactose”.
Danish: Tabletkernen: vandfri lactose, croscarmellosenatrium (E468), hypromellose (E464), mikrokrystallinsk cellulose (E460), magnesiumstearat (E572) - se punkt 2 ”Capecitabine medac indeholder lactose”.
English: See section 5.1 for details of major studies, including study designs and major efficacy results.
Danish: Detaljeret beskrivelse af de største forsøg, inklusive forsøgsdesign og overordnede effektresultater, findes i pkt.
English: Median PFS was 7.6 months for FOLFIRI, 5.9 months for mIFL (p = 0.004) for the comparison with FOLFIRI), and 5.8 months for XELIRI (p = 0.015).
Danish: Den mediane progressionsfri overlevelse var 7,6 måneder for FOLFIRI, 5,9 måneder for mIFL (p = 0,004 ved sammenligning med FOLFIRI) og 5,8 måneder for XELIRI (p = 0,015).
English: Capecitabine monotherapy
Danish: Capecitabin-monoterapi
English: P = 0.45
Danish: 25,5 måneder p = 0,45
English: In this treatment subgroup comparison, XELOX plus bevacizumab was similar compared to FOLFOX-4 plus bevacizumab in terms of PFS (hazard ratio 1.01; 97.5 % CI 0.84 - 1.22).
Danish: Sammenligningen viste, at XELOX plus bevacizumab svarede til FOLFOX-4 plus bevacizumab med hensyn til PFS (hazard ratio 1,01; 97,5 % konfidensinterval 0,84 - 1,22).
English: • joint swelling or stiffness, bone pain, muscle weakness or stiffness
Danish: • hævede eller stive led, knoglesmerter, muskelsvaghed eller stivhed
English: In the largest study (BICC-C), patients were randomised to receive either open label FOLFIRI (n = 144), bolus 5-FU (mIFL) (n = 145) or XELIRI (n = 141) and were additionally randomised to receive either double-blind treatment with celecoxib or placebo.
Danish: I det største studie (studie BICC-C) blev patienterne randomiseret til ublindet enten at få FOLFIRI (n = 144), bolus-5-FU (mIFL) (n = 145) eller XELIRI (n = 141).
English: If you forget to take Capecitabine medac
Danish: Hvis du har glemt at tage Capecitabine medac
English: • confusional state, panic attacks, depressed mood, decreased libido
Danish: • forvirring, panikanfald, deprimeret sindstilstand, nedsat seksualdrift
English: Capecitabine medac contains sodium
Danish: Capecitabine medac indeholder natrium
English: Standard and reduced dose calculations according to body surface area for starting doses of Capecitabine medac of 1,250 mg/m² and 1,000 mg/m² are provided in tables 1 and 2, respectively.
Danish: Standard og reducerede initialdosisberegninger af Capecitabine medac på 1.250 mg/m² og 1.000 mg/m² ud fra legemsoverfladeareal er anført i henholdsvis tabel 1 og 2.
English: • skin rash, hair loss (alopecia), skin reddening, dry skin, itching (pruritus), skin discolouration,
Danish: • hududslæt, lettere hårtab (alopeci), hudrødmen, tør hud, kløe (pruritus), misfarvning af huden,
English: • eye irritation, increased tears, eye redness (conjunctivitis)
Danish: • øjenirritationer, øget tåreflåd, røde øjne (konjunktivitis)
English: The primary efficacy analyses in the per protocol population demonstrated non-inferiority in overall survival for capecitabine- vs 5-FU-based regimens (hazard ratio 0.86; 95 % CI 0.8 - 0.99) and for oxaliplatin- vs cisplatin-based regimens (hazard ratio 0.92; 95 % CI 0.80 - 1.1).
Danish: Den primære effektanalyse i per protokolpopulationen demonstrerede non-inferioritet i samlet overlevelse for capecitabin versus 5-FU-regimerne (hazard ratio 0,86; 95 % konfidensinterval 0,8 - 0,99) og for oxaliplatin mod cisplatinbaserede regimer (hazard ratio 0,92; 95 % konfidensinterval 0,80 - 1,1).
English: 5 mg/kg intravenous 30 - 90 mins
Danish: 5 mg/kg intravenøsover 30-90 min.
English: A meta-analysis of 14 clinical trials with data from over 4,700 patients treated with capecitabine monotherapy or capecitabine in combination with different chemotherapy regimens in multiple indications (colon, colorectal, gastric and breast cancer) showed that HFS (all grades) occurred in 2,066 (43 %) patients after a median time of 239 [95 % CI 201, 288] days after starting treatment with capecitabine.
Danish: En metaanalyse af 14 kliniske studier med data fra mere end 4.700 patienter, som er blevet behandlet med capecitabin-monoterapi eller capecitabin i kombination med forskellige kemoterapiregimer inden for flere indikationer (kolonkræft, kolorektalkræft, ventrikelkræft og brystkræft) viste, at HFS (alle grader) forekom hos 2.066 (43 %) patienter gennemsnitligt 239 [95 % konfidensinterval 201, 288] dage efter behandlingsstart med capecitabin.
English: In addition to the ADRs described in tables 4 and 5, and based on the above pooled analysis from clinical safety data from 7 clinical trials, encephalopathy was also associated with the use of capecitabine monotherapy with an incidence of less than 0.1 %.
Danish: Baseret på en samlet analyse af kliniske sikkerhedsdata fra 7 kliniske studier blev der ud over de bivirkninger, som er anført i tabel 4 og 5, observeret encephalopati som værende forbundet med anvendelsen af capecitabin-monoterapi med en hyppighed på mindre end 0,1 %.
English: Patients with renal impairment (see section 4.2, 4.4, and 5.2) An analysis of safety data in patients treated with capecitabine monotherapy (colorectal cancer) with baseline renal impairment showed an increase in the incidence of treatment-related grade 3 and 4 adverse reactions compared to patients with normal renal function (36 % in patients without renal impairment n = 268, vs. 41 % in mild n = 257 and 54 % in moderate n = 59, respectively) (see section 5.2).
Danish: 4.2, 4.4 og 5.2) En analyse af sikkerhedsdata fra patienter, som fik capecitabin-monoterapi (kolorektalkræft), og som havde nyreinsufficiens ved baseline, viste, at der var en stigning i hyppigheden af behandlingsrelaterede bivirkninger, grad 3 og 4, sammenlignet med patienter med normal nyrefunktion (36 % hos patienter uden nyreinsufficiens n = 268 vs. henholdsvis 41 % hos patienter med let nyreinsufficiens n = 257 og 54 % hos patienter med moderat nyreinsufficiens n = 59) (se pkt.
English: In first-line treatment the median PFS in the intent-to-treat population was 5.8 months (95 %CI 5.1 - 6.2 months) for capecitabine monotherapy and 7.8 months (95 %CI 7.0-8.3 months; p = 0.0002) for XELIRI.
Danish: I 1. linjebehandlingen var den mediane PFS i intent-to-treat-populationen 5,8 måneder (95 % konfidensinterval 5,16,2 måneder) for capecitabin-monoterapi og 7,8 måneder (95 % konfidensinterval 7,0 - 8,3 måneder; p = 0,0002) for XELIRI.
English: Aluminium/aluminium blisters
Danish: Aluminium/aluminium-blistere 3 år
English: Dose modifications for toxicity when capecitabine is used as a 3-weekly cycle in combination with other medicinal products
Danish: Dosisændringer på grund af toksicitet, når capecitabin anvendes i en tre ugers-serie i kombination med andre lægemidler
English: A meta-analysis of 14 clinical trials with data from over 4,700 patients treated with capecitabine monotherapy or capecitabine in combination with different chemotherapy regimens in multiple indications (colon, colorectal, gastric and breast cancer) showed that patients on capecitabine who developed HFS had a longer overall survival compared to patients who did not develop HFS: median overall survival 1,100 days (95 % CI 1,007;1,200) vs 691 days (95 % CI 638;754) with a hazard ratio of 0.61 (95 % CI 0.56; 0.66).
Danish: En metaanalyse af 14 kliniske studier med data fra mere end 4.700 patienter, som er blevet behandlet med capecitabin-monoterapi eller capecitabin i kombination med forskellige kemoterapiregimer inden for flere indikationer (kolonkræft, kolorektalkræft, ventrikelkræft og brystkræft) viste, at patienter behandlet med capecitabin, som udviklede hånd- og fodsyndrom (HFS), havde en længere samlet overlevelse sammenlignet med patienter, som ikke udviklede hånd- og fodsyndrom: den mediane samlede overlevelse var 1.100 dage (95 % konfidensinterval 1.007; 1.200) versus 691 dage (95 % konfidensinterval 638; 754).
English: Hypokalaemia, Appetite disorder, Malnutrition, Hypertriglyceridaemia
Danish: Hypokaliæmi, Appetitforstyrrelser, Underernæring, Hypertriglyceridæmi
English: The results of a meta-analysis of 14 clinical trials with data from over 4,700 patients treated with capecitabine showed that in all studies combined, female gender was statistically significantly associated with an increased risk of developing HFS and diarrhoea and with a decreased risk of developing neutropenia.
Danish: Resultaterne fra en metaanalyse af 14 kliniske studier med data fra mere end 4.700 patienter, som er blevet behandlet med capecitabin, viste, at i alle studier kombineret var kvindeligt køn statistisk signifikant associeret med en øget risiko for udviklingen af HFS og diarré og med en faldende risiko for at udvikle neutropeni.
English: Oxaliplatin 85 mg/m² intravenous 2 hr
Danish: Oxaliplatin 85 mg/m² intravenøs over 2 timer
English: • headache, sleepiness, dizziness, abnormal sensation in the skin (numbness or tingling sensation),
Danish: • hovedpine, søvnighed, svimmelhed, unormal fornemmelse i huden (følelsesløshed eller prikkende fornemmelse), smagsforandringer
English: 7.5 mg/kg intravenous 30 - 90 mins
Danish: 7,5 mg/kg intravenøs over 3090 min
English: • sleeplessness (insomnia), depression
Danish: • søvnløshed, depression
English: PVC/PVdC/Aluminium blisters
Danish: PVC/PVdC/aluminium-blistere 3 år
English: Data from a multicentre, randomised, controlled phase II study (AIO KRK 0604) supports the use of capecitabine at a starting dose of 800 mg/m² for 2 weeks every 3 weeks in combination with irinotecan and bevacizumab for the first-line treatment of patients with metastatic colorectal cancer.
Danish: Data fra et randomiseret, kontrolleret fase II-multicenterstudie (AIO KRK 0604) støtter anvendelsen af en initial capecitabin-dosis på 800 mg/m² i 2 uger hver 3. uge i kombination med irinotecan og bevacizumab som 1. linjebehandling af patienter med metastatisk kolorektalkræft.
English: Table 8 Key efficacy results for AIO KRK study
Danish: Tabel 8: Nøgleresultater for effekt fra AIO KRK-studiet XELOX + bevacizumab
English: • inflammation leading to dysfunction or obstruction in bile secretion (cholestatic hepatitis)
Danish: • betændelse, der fører til nedsat funktion eller tilstopning af galdevejene (kolestatisk hepatitis),
English: -2nd appearance -3rd appearance -4th appearance
Danish: - ved 2. forekomst - ved 3. forekomst - ved 4. forekomst
English: Capecitabine medac is used in the treatment of colon, rectal, gastric, or breast cancers.
Danish: Capecitabine medac anvendes til behandling af kræft i tyktarm, endetarm, mave eller bryst.
English: • blood clots in the veins in the lung (pulmonary embolism), collapsed lung, coughing up blood,
Danish: • blodpropper i venerne i lungerne (pulmonær emboli), lungekollaps, ophostning af blod, astma,