FrancophonIA/ELRC3.0 huggingface dataset:
English: In children the dose of Cubicin for skin or soft tissue infection without bacteraemia depends on the child's age and ranges between 5 and 10 mg/kg once a day.
Slovenian: Pri otrocih je odmerek zdravila Cubicin pri okužbah kože ali mehkih tkiv brez bakteriemije odvisen od njihove starosti in znaša med 5 in 10 mg/kg enkrat na dan.
English: How is Cubicin used?
Slovenian: Kako se zdravilo Cubicin uporablja?
English: How does Cubicin work?
Slovenian: Kako zdravilo Cubicin deluje?
English: For endocarditis and for skin or soft tissue infection with bacteraemia, the dose is 6 mg/kg once a day.
Slovenian: Pri endokarditisu ali okužbah kože oziroma mehkih tkiv z bakteriemijo znaša odmerek 6 mg/kg enkrat na dan.
English: In adults, for skin or soft tissue infections without bacteraemia, Cubicin is given at a dose of 4 mg/kg body weight once a day.
Slovenian: Pri odraslih se pri okužbah kože ali mehkih tkiv brez bakteriemije zdravilo Cubicin daje v odmerku 4 mg/kg telesne mase enkrat na dan.
English: Higher doses (between 7 and 12 mg/kg once a day) are used if the skin or soft tissue infection is associated with bacteraemia.
Slovenian: Če je okužba kože ali mehkih tkiv povezana z bakteriemijo, se uporabljajo večji odmerki (med 7 in 12 mg/kg enkrat na dan).
English: 30 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom sedation and analgesia depend on the dose that is used.
Slovenian: 30 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom od njihove telesne mase.
English: It also depends on the use and the way it is given.
Slovenian: Odmerek je odvisen tudi od uporabe in načina dajanja zdravila.
English: • as premedication before inducing general anaesthesia.
Slovenian: • kot premedikacija, ki se daje pred uvedbo splošne anestezije.
English: The full EPAR for Cepedex can be found on the Agency's website: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila Cepedex je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
English: It works by attaching to receptors known as alpha2-adrenergic receptors and preventing the release of the neurotransmitter noradrenaline from nerve cells in the body.
Slovenian: Deluje tako, da se veže na receptorje, imenovane alfa2-adrenoreceptorji, in preprečuje sproščanje živčnega prenašalca noradrenalina iz živčnih celic v telesu.
English: This is a summary of the European public assessment report (EPAR) for Cepedex.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Cepedex.
English: The Agency's Committee for Medicinal Products for Veterinary Use (CVMP) concluded that, in accordance with EU requirements, Cepedex has been shown to have comparable quality to Dexdomitor.
Slovenian: Odbor za zdravila za uporabo v veterinarski medicini (CVMP) pri agenciji je zaključil, da je bilo v skladu z zahtevami EU dokazano, da ima zdravilo Cepedex primerljivo raven kakovosti kot zdravilo Dexdomitor.
English: Cepedex dexmedetomidine
Slovenian: Cepedex deksmedetomidin
English: Cepedex is an alpha2-adrenoceptor agonist.
Slovenian: Zdravilo Cepedex je agonist alfa2-adrenoreceptorja.
English: The company provided information on the quality and manufacture of Cepedex.
Slovenian: Družba je priskrbela podatke o kakovosti in proizvodnji zdravila Cepedex.
English: • when carrying out mildly to moderately painful procedures and examinations that require the animal to be restrained or sedated and made less sensitive to pain (analgesia).
Slovenian: • pri blago do zmerno bolečih posegih in pregledih, pri katerih so potrebni mirovanje in sedacija živali ter zmanjšanje občutljivosti za bolečino (analgezija).
English: Cepedex is a medicine used to sedate (calm down) dogs and cats in the following situations:
Slovenian: Zdravilo Cepedex se uporablja za sedacijo (pomiritev) psov in mačk v naslednjih primerih:
English: What are the benefits and risks of Cepedex?
Slovenian: Kakšne so koristi in tveganja, povezani z zdravilom Cepedex?
English: The Committee recommended that Cepedex be approved for use in the EU.
Slovenian: Priporočil je, da se zdravilo Cepedex odobri za uporabo v EU.
English: For dogs the dose depends on their body surface area (calculated using bodyweight) and in cats it is based on bodyweight.
Slovenian: Pri psih je odmerek odvisen od njihove telesne površine (izračunane na podlagi telesne mase), pri mačkah pa
English: Cepedex can also be used in dogs to provide pain relief and deep sedation when carrying out medical procedures and minor surgery where it is used in combination with butorphanol (a sedative and analgesic).
Slovenian: Zdravilo Cepedex se lahko pri psih uporablja tudi za lajšanje bolečine in globoko sedacijo pri zdravstvenih in manjših kirurških posegih, in sicer v kombinaciji z butorfanolom (sedativom in analgetikom).
English: It is not intended to provide practical advice on how to use Cepedex.
Slovenian: Povzetek ni namenjen zagotavljanju praktičnih nasvetov o njegovi uporabi.
English: Cepedex is used in non-invasive procedures which do not involve breaking the skin or a body cavity.
Slovenian: Zdravilo Cepedex se uporablja pri neinvazivnih posegih, kar pomeni, da se pri postopku ne predre kože ali stene telesne votline;
English: Because Cepedex is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine's.
Slovenian: Ker je zdravilo Cepedex generično zdravilo in je biološko enakovredno referenčnemu zdravilu, so koristi in tveganja enaki kot pri referenčnem zdravilu.
English: What is Cepedex and what is it used for?
Slovenian: Kaj je zdravilo Cepedex in za kaj se uporablja?
English: This means that Cepedex is similar to a ‘reference medicine' already authorised in the EU called Dexdomitor.
Slovenian: To pomeni, da je podobno referenčnemu zdravilu, ki je že odobreno v Evropski uniji (EU), in sicer zdravilu Dexdomitor.
English: Other information about Cepedex?
Slovenian: Druge informacije o zdravilu Cepedex
English: Cepedex contains the active substance dexmedetomidine and is a ‘generic medicine'.
Slovenian: Zdravilo Cepedex vsebuje zdravilno učinkovino deksmedetomidin in je „generično zdravilo“.
English: In dogs, Cepedex is given by injection into a vein or a muscle.
Slovenian: Psom se zdravilo Cepedex daje z injiciranjem v veno ali mišico, mačkam pa z injiciranjem v mišico.
English: Why is Cepedex approved?
Slovenian: Zakaj je bilo zdravilo Cepedex odobreno?
English: For more information about treatment with Cepedex, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Cepedex naj lastniki ali skrbniki živali preberejo navodilo za uporabo ali se posvetujejo z veterinarjem ali farmacevtom.
English: For practical information about using Cepedex, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Slovenian: Za praktične informacije o uporabi zdravila Cepedex naj lastniki ali skrbniki živali preberejo navodilo za uporabo ali se posvetujejo z veterinarjem ali farmacevtom.
English: Cepedex is available as a solution for injection and can only be obtained with a prescription.
Slovenian: Zdravilo Cepedex je na voljo v obliki raztopine za injiciranje, predpisovanje in izdaja zdravila je le na recept.
English: Safety information has been included in the summary of product characteristics and the package leaflet for Cepedex, including the appropriate precautions to be followed by healthcare professionals and animal owners or keepers when giving Cepedex.
Slovenian: V povzetek glavnih značilnosti zdravila Cepedex in navodilo za njegovo uporabo so bile vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in lastniki ali skrbniki živali pri dajanju tega zdravila.
English: How does Cepedex work?
Slovenian: Kako zdravilo Cepedex deluje?
English: How has Cepedex been studied?
Slovenian: Kako je bilo zdravilo Cepedex raziskano?
English: How is Cepedex used?
Slovenian: Kako se zdravilo Cepedex uporablja?
English: No additional studies were needed as Cepedex is a generic medicine that is given by injection, is similar in composition to, and contains the same active substance as the reference medicine, Dexdomitor.
Slovenian: Ker je zdravilo Cepedex generično zdravilo, ki se daje z injiciranjem, je po sestavi podobno referenčnemu zdravilu Dexdomitor in tudi vsebuje isto zdravilno učinkovino, niso bile potrebne nobene dodatne študije.
English: The European Commission granted a marketing authorisation valid throughout the EU for Cepedex on 13 December 2016.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Cepedex, veljavno po vsej Evropski uniji, izdala
English: The duration and depth of
Slovenian: Trajanje in globina sedacije in analgezije sta odvisna od uporabljenega odmerka.
English: 1 pre-filled syringe of 150 mg + 2 needles, 1 prefilled syringe 100 mg + 2 needles
Slovenian: 1 napolnjena injekcijska brizga s 150 mg + 2 igli, 1 napolnjena injekcijska brizga s 100 mg + 2 igli
English: Initiation pack:
Slovenian: Uvajalno pakiranje:
English: Strength Pharmaceutical Form Route of Administration
Slovenian: Farmacevtska oblika Pot uporabe Ovojnina
English: Xeplion
Slovenian: Jakost
English: Hygienic measures may reduce the risk of porcine coccidiosis.
Slovenian: Higienski ukrepi lahko zmanjšajo tveganje za kokcidiozo prašičev.
English: Iron is an essential micronutrient.
Slovenian: Železo je bistveno mikrohranilo.
English: Inject intramuscularly behind the ear into the neck.
Slovenian: Injicirajte intramuskularno za ušesom v vrat.
English: Frequent and repeated use of antiprotozoals from the same class may lead to the development of resistance.
Slovenian: Pogosta in ponavljajoča se uporaba antiprotozoikov; iz istega razreda lahko vodi do razvoja odpornosti.
English: The rubber stopper of the vial may be safely punctured up to 30 times.
Slovenian: Zamašek viale se lahko varno prebode do 30-krat.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/19/239/001
Slovenian: ŠTEVILKA(E) DOVOLJENJ(A) ZA PROMET EU/2/19/239/001
English: Pull out the needle and release the skin.
Slovenian: Izvlecite iglo in spustite kožo.
English: The active substances in Baycox Iron are allowed substances as described in table 1 of the annex to Commission Regulation (EU) No 37/2010:
Slovenian: Učinkovine v Baycox Iron so dovoljene učinkovine, kot so navedene v tabeli 1(dovoljene snovi) priloge Uredbe Komisije (EU) št. 37/2010:
English: To ensure the correct dosage, the piglets' body weight should be determined as accurately as possible.
Slovenian: Za zagotovitev pravilnega odmerjanja je treba telesno maso pujskov določiti čim natančneje.
English: Iron is not readily eliminated; most of it is re-used, while only small amounts are eliminated.
Slovenian: Železose običajno ne izloča; večina se ga ponovno uporabi, ob tem se izločijo le majhne količine.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 20/05/2019
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum pridobitve dovoljenja za promet: 20/05/2019
English: 4941 SJ Raamsdonksveer Netherlands
Slovenian: 4941 SJ Raamsdonksveer Nizozemska
English: There is no specific organ for iron excretion.
Slovenian: Za izločanje železa ni posebnega organa.
English: The responsible veterinarian should take into account the results of clinical examinations and/or analysis of faecal samples and/or histological findings, which confirmed the presence of C. suis in a previous infection episode on the farm.
Slovenian: Odgovorni veterinar mora upoštevati rezultate kliničnih preiskav in / ali analiz vzorcev blata in / ali histoloških ugotovitev, ki so potrdile prisotnost C. suis v predhodnem primeru okužbe na kmetiji.
English: From 72 h onwards, this is followed by a very slowly decreasing plasma concentration with a calculated mean half-life of 960 h, indicating equilibrium conditions.
Slovenian: Od 72. ur dalje sledi počasno zniževanje plazemske koncentracije z izračunanim razpolovnim časom 960 ur, kar kaže na stanje ravnovesja.
English: In intensive farming conditions, piglets do not have access to other sources of iron, such as soil.
Slovenian: V intenzivnih proizvodnih sistemih pujski nimajo dostopa do drugih virov železa, kot so tla.
English: Cardboard box with 1 vial.
Slovenian: Kartonska škatla z 1 vialo.
English: Meat and offal: 53 days.
Slovenian: Meso in organi: 53 dni.
English: For porcine species the fat MRL relates to ‘skin and fat in natural proportions'.
Slovenian: Za prašiče se MRL za maščobo nanaša na kožo in maščobo v naravnih razmerjih“.
English: Wash hands after use and/or spillage.
Slovenian: Po uporabi in / ali razlitju si umijte roke.
English: Piglet deaths have been reported which have been attributed to an increased susceptibility to infection due to temporary blocking of the reticuloendothelial system.
Slovenian: Poročano je bilo o poginih pujskov, ki so bili pripisani povečani dovzetnosti za okužbe zaradi začasne blokade retikuloendotelijskega sistema.
English: Therefore, piglets should be supplemented with iron.
Slovenian: Zato je treba pujskom železo dodajati.
English: (as gleptoferron
Slovenian: (kot gleptoferon
English: Anaphylactic reactions may occur rarely.
Slovenian: Redko se lahko pojavijo anafilaktične reakcije.
English: Accidental self-injection may cause adverse effects.
Slovenian: Nenamerno samo-injciranje lahko povzroči neželene učinke.
English: The primary routes of iron excretion are via faeces and urine, there are additional small losses in sweat, hair and nails.
Slovenian: Glavne poti izločanja železa so blato in urin, dodatne manjše izgube preko znoja, las in nohtov.
English: Introduce the needle at an angle of 90° and inject the product.
Slovenian: Iglo vstavite pod kotom 90 ° in zdravilo injicirajte.
English: It is therefore recommended to concomitantly improve the hygiene conditions in the farm concerned, particularly by increasing dryness and cleanliness.
Slovenian: Zato je priporočljivo sočasno izboljšanje higienskih pogojev na kmetiji, s poudarkom na suhem in čistem okolju.
English: Iron (as gleptoferron)
Slovenian: Železo (kot gleptoferon)
English: It is a constituent of haemoglobin and myoglobin and has a key role in enzymes, such as cytochromes, catalases, and peroxidases.
Slovenian: Je sestavina hemoglobina in mioglobina ter ima ključno vlogo pri encimih, kot so citokromi, katalaze in peroksidaze.
English: The product is not recommended for use in piglets weighing less than 0.9 kg.
Slovenian: Uporaba zdravila ni priporočljiva za pujske, ki tehtajo manj kot 0,9 kg.
English: Pregnant women and women intending to conceive should avoid contact with the veterinary medicinal product, especially accidental self-injection.
Slovenian: Nosečnice in ženske, ki nameravajo zanositi, naj se izogibajo stiku z zdravilom, še posebej nenamernemu samo-injiciranju.
English: 5 mg For the full list of excipients, see section 6.1.
Slovenian: Za celoten seznam pomožnih snovi, glejte poglavje 6.1.
English: Therefore, the product should be administered to all animals before the expected onset of clinical signs, that is, in the prepatent period.
Slovenian: Zato je treba živali zdravilo dati pred pričakovanim pojavom kliničnih znakov, torej v latentnem obdobju.
English: PHARMACEUTICAL FORM Suspension for injection
Slovenian: FARMACEVTSKA OBLIKA suspenzija za injiciranje
English: Piglets are born with only moderate stores of iron and the milk consumed by piglets is a poor source of iron.
Slovenian: Pujski se skotijo le z zmernimi zalogami železa, mleko, ki ga uživajo pujski, pa je slab vir železa.
English: Once clinical signs of coccidiosis are evident, damage to the small intestine will have already occurred.
Slovenian: Ko so opazni klinični znaki kokcidioze, so se že pojavile poškodbe tankega črevesa.
English: The doser on the device should be adjusted according to the piglets' weight prior to injection.
Slovenian: Odmernik naprave mora biti prilagojen glede na maso pujska pred injiciranjem.
English: In some cases (n=13 out of n=29 animals treated multiple times with 3 times the recommended dose) this resulted in death of the animals.
Slovenian: V nekaterih primerih (n = 13 od n = 29 živali, zdravljenih večkrat s 3-kratnim priporočenim terapevtskim odmerkom), je to povzročilo pogin živali, kar je verjetno posledica preobremenitve telesa z železom.
English: It has coccidiocidal activity against all intracellular development stages of the genus Cystoisospora, that is, merogony (asexual multiplication) and gamogony (sexual phase).
Slovenian: Ima kokcidiocidno aktivnost proti vsem intracelularnim razvojnim stadijem rodu Cystoisospora, to je merogonijo (nespolno razmnoževanje) in gamogonijo (spolna faza).
English: These deaths have been associated with genetic factors or deficiencies of vitamin E and/or selenium.
Slovenian: Ti pogini so povezani z genskimi dejavniki ali pomanjkanjem vitamina E in/ali selena.
English: All mammalian food producing species
Slovenian: Vse vrste sesalcev za proizvodnjo hrane
English: Total plasma exposure reaches 3868 to 4097 mg*h/l.
Slovenian: Skupna plazemska izpostavljenost znaša 3868 do 4097 mg*h/l.
English: It is not recommended to use the veterinary medicinal product in piglets weighing less than 0.9 kg, as the efficacy and safety of the product has not been evaluated in such small piglets.
Slovenian: Uporaba pri pujskih, ki tehtajo manj kot 0,9 kg ni priporočljiva, saj učinkovitost in varnost zdravila pri njih nista bili ovrednoteni.
English: Special precautions for use in animals: The product must not be administered more than once.
Slovenian: Posebni previdnostni ukrepi za uporabo pri živalih: Zdravila se ne sme dati več kot enkrat.
English: In case of overdose, supportive measures such as chelating agents (e.g. deferoxamine) can be used.
Slovenian: V primeru prevelikega odmerjanja je mogoče uporabiti podporne ukrepe, kot je dajanje kelatnih sredstev (npr. deferoksamina).
English: People with known hypersensitivity to iron (as gleptoferron complex) should avoid contact with the veterinary medicinal product.
Slovenian: Osebe z znano preobčutljivostjo na železo (kot kompleks gleptoferona) naj se izogibajo stiku z zdravilom za uporabo v veterinarski medicini.
English: In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Slovenian: V primeru nenamernega samo-injiciranja poiščite takoj zdravniško pomoč in zdravniku pokažite navodilo za uporabo ali ovojnino.
English: Total plasma exposure reaches between 1046 and 1245 mg*h/l.
Slovenian: Skupna plazemska izpostavljenost znaša med 1046 in 1245 mg* h/l.
English: Not for use in animals from which eggs are produced for human consumption.
Slovenian: Ni za uporabo pri živalih, katerih jajca se uporabljajo za prehrano ljudi.
English: In the blood, free iron (III)-ions bind to transferrin (transport form) and are mainly used for the synthesis of haemoglobin.
Slovenian: V krvi se prosti železovi III-ioni vežejo na transferin (transportna oblika) in se večinoma uporabljajo za sintezo hemoglobina.
English: Toltrazuril reaches peak plasma concentrations of 4.17 to 6.43 mg/l within 5 days.
Slovenian: Toltrazuril doseže največjo koncentracijo v plazmi 4,17 do 6,43mg/l v 5 dneh.
English: Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
Slovenian: Ne uporabite v primeru preobčutljivosti na učinkovine ali katero koli pomožno snov.
English: Toltrazuril and its metabolites are mainly eliminated in faeces via biliary excretion and to a small extent via urine.
Slovenian: Toltrazuril in njegovi metaboliti se v glavnem izločajo z blatom z izločanjem žolča in v manjšem obsegu preko urina.
English: Should clinical signs be observed in the two weeks following administration of the product, contact your veterinarian to obtain an appropriate differential diagnosis.
Slovenian: Če opazite klinične znake v dveh tednih po zdravljenju z zdravilom, se posvetujte z veterinarjem, da dobite ustrezno diferencialno diagnozo.
English: Transferrin-iron saturation levels may lead to increased susceptibility for (systemic) bacterial infection, pain, inflammatory reactions as well as abscess formation at the injection site.
Slovenian: Stopnje nasičenja s transferinom in železom lahko privedejo do povečane dovzetnosti za (sistemsko) bakterijsko okužbo, bolečine, vnetne reakcije in nastajanje abscesov na mestu injiciranja.
English: Plasma iron concentration peaks within the first day reaching concentrations of 548 mg/l at 6 hours after injection.
Slovenian: Največje koncentracije železa v plazmi v prvem dnevu dosežejo koncentracije 548 mg/l 6 ur po injiciranju.
English: When administering the product to larger groups of animals, a multi-dosing device (with vented drawoff apparatus) is recommended.
Slovenian: Pri zdravljenju večjih skupin živali je priporočena večodmerna naprava (z odvodnim izvlečnim aparatom).
English: Pack size: Cardboard box with 1 vial of 100 ml.
Slovenian: Pakiranje: Kartonska škatla z eno vialo z 100 ml.
English: Toltrazuril-sulfone is eliminated from plasma with a half-life of about 5 to 7 days.
Slovenian: Toltrazuril-sulfon se izloča iz plazme z razpolovno dobo približno 5 do 7 dni.
English: The draw-off needle should be removed after administration.
Slovenian: Odvzemno iglo je treba po dajanju odstraniti.
English: Toltrazuril is eliminated from plasma with a halflife of about 3 to 4 days showing substantial metabolism to toltrazuril-sulfoxide and toltrazurilsulfone, the main active metabolite.
Slovenian: Toltrazuril se izloča iz plazme z razpolovno dobo 3 do 4 dni, kar kaže znatno presnovo do toltrazuril-sulfoksida in glavnega aktivnega metabolita toltrazuril-sulfona.
English: Shake well before use until a visually homogenous suspension is obtained and no residual product is adhering to (the bottom of) the glass vial.
Slovenian: Pred uporabo dobro pretresite, dokler ne dobite vizualno homogene suspenzije in na dnu steklene viale ne vidite preostanka zdravila.
English: After intramuscular injection, the iron complex is absorbed mainly into the lymphatic tissue, where it is split to release iron (III)-ions.
Slovenian: Po intramuskularni injekciji se kompleks železa absorbira predvsem v limfno tkivo, kjer se razcepi, da sprosti železov III-ion.
English: Excipients: Phenol
Slovenian: Pomožna snov: fenol
English: Only use this veterinary medicinal product where Cystoisospora suis has been historically confirmed on a farm.
Slovenian: To veterinarsko zdravilo uporabljajte le, kjer je Cystoisospora suis potrjen na kmetiji.
English: For the concurrent prevention of clinical signs of coccidiosis (such as diarrhoea) in neonatal piglets on farms with a confirmed history of coccidiosis caused by Cystoisospora suis, and prevention of iron deficiency anaemia.
Slovenian: Za sočasno preprečevanje kliničnih znakov kokcidioze (kot je diareja) pri novo skotenih pujskih na kmetijah s predhodno potrjeno obolevnostjo za kokcidiozo, ki jo povzroča Cystoisospora suis, in hkratno preprečevanje anemije zaradi pomanjkanja železa pri pujskih.
English: Not applicable.
Slovenian: prav tako ni potreben.
English: Colourless silicone-coated glass Type II vials with chlorobutyl stoppers and aluminium caps containing 100 ml.
Slovenian: Viala iz brezbarvnega stekla tipa II s silikonsko prevleko s klorobutilnim zamaškom in aluminijastimo zaporko, ki vsebuje 100 ml.
English: Free iron (III)-ions are removed from plasma with a half-life of approximately 8 hours.
Slovenian: Prosti železovi III-ioni se odstranijo iz plazme z razpolovno dobo približno 8 ur.
English: The tolerance of the veterinary medicinal product has been assessed after a single intramuscular administration of up to 5 times the recommended dose, as well as after repeated administrations.
Slovenian: Toleranca zdravila je bila ocenjena po enkratnem intramuskularnem dajanju do 5-kratnega priporočenega odmerka in po ponavljajočih se odmerkih.