FrancophonIA/ELRC3.0 huggingface dataset:
English: If allergic reactions are observed, treatment should be discontinued.
Croatian: Ako se opaze alergijske reakcije, liječenje se mora prekinuti.
English: If you experience any of the following side effects, please stop using this medicine and seek immediate medical attention as these could be signs of a reaction to the medicine.
Croatian: Ako primijetite bilo koju od slijedećih nuspojava, molimo prekinite primjenu lijeka i odmah potražite medicinsku pomoć jer ovo mogu biti znakovi reakcije na lijek.
English: What SIMBRINZA is and what it is used for
Croatian: Što je SIMBRINZA i za što se koristi
English: Should this happen, contact your doctor immediately.
Croatian: Ako se to dogodi,odmah se obratite liječniku.
English: They are classified according to the subsequent convention: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000), very rare (<1/10,000) or not known (cannot be estimated from the available data).
Croatian: Razvrstane su prema sljedećoj klasifikaciji: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000) ili nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Plasma levels decline with a half-life of approximately 2-3 hours.
Croatian: Razine u plazmi opadaju s poluvijekom od otprilike 2-3 sata.
English: It could infect the drops.
Croatian: Može doći do inficiranja kapi.
English: Missed dose If a dose is missed, treatment should be continued with the next dose as planned.
Croatian: Ako se propusti jedna doza, liječenje se mora nastaviti sa sljedećom dozom kako je planirano.
English: Maximum human plasma concentrations are <1 ng/mL and achieved within <1 hour.
Croatian: Maksimalne koncentracije u krvi kod ljudi su <1 ng/ml i postignute unutar <1 sata.
English: If you stop using SIMBRINZA the pressure in your eye will not be controlled, which could lead to loss of sight.
Croatian: Ako ste prekinuli primjenu SIMBRINZE Vaš očni tlak više neće biti pod nadzorom, što može dovesti do gubitka vida.
English: SIMBRINZA is not intended for use by children and adolescents aged below 18 years because it has not been studied in this age group.
Croatian: SIMBRINZA nije namijenjena za primjenu u djece i adolescenata ispod 18 godina starosti zato što nije bila ispitivana u toj dobnoj skupini.
English: Both substances work together to reduce pressure within the eye.
Croatian: Obje tvari djeluju zajedno na snižavanje tlaka u oku.
English: • Severe skin reactions, including rash or redness or itching on your body or eyes
Croatian: • Teške kožne reakcije, uključujući osip ili crvenilo ili svrbež na tijelu ili očima
English: The only adverse reaction reported to date was hypotension.
Croatian: Jedina do sada prijavljena nuspojava je hipotenzija.
English: To reduce the amount of medicine that could come into the rest of the body after application of the eye drop, close your eye and apply gentle pressure to the corner of the eye next to the nose with a finger for at least 2 minutes.
Croatian: Kako bi smanjili količinu lijeka koji bi mogao prijeći u ostatak tijela nakon primjene kapi za oko, zatvorite oko i lagano pritisnite prstom kut oka okrenut nosu na najmanje 2 minute.
English: Do not squeeze the bottle: it is designed so that a gentle press on the bottom is all that it needs (picture 2).
Croatian: Bocu nemojte stiskati: ona je izrađena tako da samo trebate pritisnuti njeno dno (slika 2).
English: You should also tell your doctor if the dose of any of your current medicines is changed.
Croatian: Trebate obavijestiti svoga liječnika i ako mijenjate dozu bilo kojeg lijeka koji uzimate.
English: The Cmax, AUC and elimination half-life of brimonidine are similar in elderly (>65 years of age) subjects compared to young adults.
Croatian: Cmax, AUC i poluvijek eliminacije brimonidina u starijih osoba (>65 godina starosti) slični su onima u mladih odraslih osoba.
English: If overdose with SIMBRINZA occurs treatment should be symptomatic and supportive.
Croatian: Nastupi li predoziranje SIMBRINZOM, liječenje mora biti simptomatsko i potporno.
English: Ask your optometrist (optician) or pharmacist how to throw away medicines you no longer use.
Croatian: Pitajte svog optometristu (optičara) ili ljekarnika kako baciti lijekove koje više ne koristite.
English: Patients should be instructed to shake the bottle well before use.
Croatian: Bolesnike treba uputiti da prije uporabe dobro protresu bocu.
English: The recommended dose is one drop in the affected eye or eyes two times a day.
Croatian: Preporučena doza je jedna kap u oboljelo oko ili oči dva puta na dan.
English: If you feel abnormal eye sensation, stinging or pain in the eye after using this medicine, talk to your doctor.
Croatian: U slučaju neuobičajenog osjećaja u oku, bockanja ili boli u oku nakon primjene ovog lijeka obratite se svom liječniku.
English: In rats and monkeys, urinary metabolites accounted for 60 to 75% of oral or intravenous doses.
Croatian: Kod štakora i majmuna, razina metabolita u urinu bila je 60 do 75% oralne ili intravenozne doze.
English: Data in rats showed some biliary excretion (about 30%), primarily as metabolites.
Croatian: Podaci kod štakora pokazali su određeno izlučivanje u žuč (oko 30%), prvenstveno u obliku metabolita.
English: Brinzolamide is primarily eliminated in urine unchanged.
Croatian: Brinzolamid se prvenstveno eliminira u urin u nepromijenjenom obliku.
English: All treatment differences (SIMBRINZA versus individual components) were statistically significant with p=0.0001 or less.
Croatian: Sve razlike među lijekovima (SIMBRINZA u odnosu na pojedine komponente) bile su statistički značajne uz vrijednost p=0,0001 ili manju.
English: Other medicines and SIMBRINZA
Croatian: Drugi lijekovi i SIMBRINZA
English: Women who may become pregnant are advised to use effective contraception during SIMBRINZA treatment.
Croatian: Ženama koje mogu zatrudnjeti preporučuje se korištenje učinkovite kontracepcije tijekom liječenja SIMBRINZOM.
English: Throw away the bottle 4 weeks after first opening to prevent infections and use a new bottle.
Croatian: Da bi se spriječile infekcije, bočicu bacite 4 tjedna nakon prvog otvaranja i uzmite novu bočicu.
English: Treatment of children 2 years and above (especially those in the 2-7 age range and/or weighing <20 kg) is not recommended because of the potential for central nervous system-related side effects (see section 4.9).
Croatian: Liječenje djece od navršene druge godine nadalje (posebice one u dobnom rasponu od 2 do 7 godina i/ili težine <20 kg) se ne preporučuje zbog mogućih nuspojava povezanih sa središnjim živčanim sustavom (vidjeti dio 4.9).
English: Do not use SIMBRINZA unless clearly indicated by your doctor.
Croatian: Ne koristite SIMBRINZU osim u slučaju da to izričito traži Vaš liječnik.
English: Brinzolamide is moderately (about 60%) bound to human plasma proteins.
Croatian: Brinzolamid se umjereno (oko 60%) veže na proteine plazme kod ljudi.
English: 1, motor dysfunction
Croatian: 1, motorička disfunkcija
English: Visit
Croatian: Posjet
English: The potential for interactions must be considered in patients receiving SIMBRINZA.
Croatian: Mora se razmotriti mogućnost interakcija u bolesnika koji primaju SIMBRINZU.
English: The frequency of an allergic reaction to the medicine is not known (frequency cannot be estimated from the available data).
Croatian: Učestalost alergijskih reakcija na lijek nije poznata (učestalost se ne može procijeniti iz dostupnih podataka).
English: The IOP-lowering effect of brimonidine may be longer.
Croatian: Učinak brimonidina na sniženje IOT-a može trajati duže.
English: This may result in a decrease in systemic side effects and an increase in local activity (see section 4.4).
Croatian: To može rezultirati smanjenjem sistemskih nuspojava i povećanjem lokalnog djelovanja (vidjeti dio 4.4).
English: Given the low systemic exposure to brimonidine following topical ocular administration, it is expected that changes in plasma exposure would not be clinically relevant.
Croatian: Imajući u vidu malu sistemsku izloženost brimonidinu nakon topikalne primjene u oko, očekuje se da promjene izloženosti u plazmi ne bi bile klinički značajne.
English: Patients should be instructed not to swallow SIMBRINZA.
Croatian: Bolesnike se mora uputiti da ne gutaju SIMBRINZU.
English: It is particularly important that the medicine is not used in children under the age of 2 years (see section ‘Do not use SIMBRINZA' above) because it is unlikely to be safe.
Croatian: Posebno je važno da se ovaj lijek ne primjenjuje u djece ispod 2 godine starosti (Pogledajte dio „Nemojte primjenjivati SIMBRINZU“ iznad) zato što nije vjerojatno da je njegova primjena u toj dobi sigurna.
English: What SIMBRINZA is and what it is used for What you need to know before you use SIMBRINZA How to use SIMBRINZA
Croatian: Što je SIMBRINZA i za što se koristi Što morate znati prije nego počnete primjenjivati SIMBRINZU
English: Uncommon: hypotension Very rare: hypertension
Croatian: Manje često: hipotenzija Vrlo rijetko: hipertenzija
English: If you are using other eye drops as well as SIMBRINZA, wait at least five minutes between using SIMBRINZA and the other drops.
Croatian: Ako primjenjujete druge kapi za oko uz SIMBRINZU, pričekajte najmanje 5 minuta između primjene SIMBRINZE i ostalih kapi.
English: When nasolacrimal occlusion is used and the eyelids are closed for 2 minutes, systemic absorption is reduced.
Croatian: Primjenom nazolakrimalne okluzije i zatvaranjem vjeđa na 2 minute smanjuje se sistemska apsorpcija.
English: If more than one topical ophthalmic medicinal product is being used, the medicinal products must be administered at least 5 minutes apart.
Croatian: Ako se primjenjuje više od jednog topikalnog oftalmičkog lijeka, lijekovi se moraju primijeniti s najmanje 5 minuta razmaka.
English: This medicine contains 0.15 mg benzalkonium chloride in each 5 ml, which is equivalent to 0.03 mg/ml.
Croatian: Ovaj lijek sadrži 0,15 mg benzalkonijevog klorida u svakih 5 ml, što odgovara 0,03 mg/ml.
English: Do not touch your eye or eyelid, surrounding areas or other surfaces with the dropper.
Croatian: Kapaljkom ne dodirujte oko ili vjeđu, okolna područja ili druge površine.
English: Effects in non-clinical reproduction and development toxicity studies were observed only at exposures considered sufficiently in excess of the maximum human exposure indicating little relevance to clinical use.
Croatian: U nekliničkim ispitivanjima reproduktivne i razvojne toksičnosti učinci su zamijećeni tek pri izloženosti koja se smatra dovoljno većom od maksimalne izloženosti ljudi, ukazujući na malu važnost za kliničku primjenu.
English: If blurred vision occurs at instillation the patient must wait until the vision clears before driving or using machines.
Croatian: Zamuti li se vid nakon ukapavanja, bolesnik mora pričekati da se vid razbistri prije nego što krene upravljati vozilom ili raditi sa strojevima.
English: Do not use this medicine after the expiry date which is stated on the bottle and the carton after “EXP”.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji iza oznake „EXP“.
English: Alpha adrenergic agonists (e.g. brimonidine tartrate), as a class, may reduce pulse and blood pressure.
Croatian: Alfa adrenergični agonisti (npr. brimonidintartarat), kao skupina, mogu smanjiti puls i krvni tlak.
English: Whole blood elimination half-life is prolonged (>100 days) in humans due to RBC carbonic anhydrase binding.
Croatian: Poluvijek eliminacije iz kompletne krvi je produljen (>100 dana) kod ljudi zbog vezivanja karboanhidraze u eritrocitima.
English: Do not use more than one drop in the affected eye(s) two times a day.
Croatian: Ne primjenjujte više od jedne kapi u oboljelo oko (oči) dva puta dnevno.
English: The potential effects following cessation of treatment with SIMBRINZA have not been studied.
Croatian: Mogući učinci nakon prekida liječenja sa SIMBRINZOM nisu ispitani.
English: If signs of serious reactions or hypersensitivity occur, the use of this medicinal product should be discontinued.
Croatian: Ako se primijete znakovi ozbiljnih reakcija ili preosjetljivosti, primjenu ovog lijeka potrebno je prekinuti.
English: 2, blood chloride increased
Croatian: 2, povišena razina klorida u krvi
English: SIMBRINZA may be used concomitantly with other topical ophthalmic medicinal products to lower intraocular pressure.
Croatian: SIMBRINZA se može koristiti istodobno s drugim topikalnim oftalmičkim lijekovima za snižavanje intraokularnog tlaka.
English: The pharmacokinetic/pharmacodynamic relationship in humans for IOP-lowering has not been established.
Croatian: Farmakokinetički/farmakodinamički odnos kod ljudi pri sniženju IOTa nije ustanovljen.
English: The medicinal product should not be injected.
Croatian: Ovaj se lijek ne smije injicirati.
English: What you need to know before you use SIMBRINZA
Croatian: Što morate znati prije nego počnete primjenjivati SIMBRINZU
English: Patients with hyperchloraemic acidosis.
Croatian: Bolesnici sa hiperkloremijskom acidozom.
English: If you are breast-feeding, SIMBRINZA may pass into your milk.
Croatian: Ako dojite, SIMBRINZA može prijeći u Vaše mlijeko.
English: You must inform your doctor if you are taking any antidepressant medicines - if you have severe kidney problems - if you have too much acidity in your blood (a condition called hyperchloraemic acidosis) - in babies and infants aged less than 2 years.
Croatian: Morate obavijestiti svog doktora ako uzimate bilo kakve antidepresive - ako imate teške tegobe s bubrezima - ako Vam je kiselost krvi prevelika (stanje koje se naziva hiperkloremijska acidoza) - kod djece i dojenčadi mlađe od 2 godine
English: Contact your doctor immediately if you develop extreme tiredness or dizziness.
Croatian: Odmah se obratite liječniku ako osjetite jaki umor ili omaglicu.
English: clomipramine, mianserin, venlafaxine and duloxetine - anaesthetics - sedatives, opiates, or barbiturates
Croatian: klomipramin, mianserin, venlafaksin i duloksetin - anestetike - sedative, opijate ili barbiturate
English: If SIMBRINZA has been accidentally swallowed then you should contact your doctor immediately.
Croatian: Ako ste slučajno progutali SIMBRINZU morate se odmah obratiti liječniku.
English: It is likely to be caused by passage of the eye drops in the nasopharynx via the nasolacrimal canal and is mainly attributable to the brinzolamide component of SIMBRINZA.
Croatian: Vjerojatno je uzrokovana prolaskom kapi za oko u nazofarinks kroz nazolakrimalni kanal i većinom se može pripisati sastojku SIMBRINZE brinzolamidu.
English: The systemic pharmacokinetics of brinzolamide and brimonidine, alone or in combination, in paediatric patients have not been studied.
Croatian: Sistemska farmakokinetika brinzolamida i brimonidina, samih ili u kombinaciji, nije ispitana u pedijatrijskih bolesnika.
English: While the duration of IOP-lowering effect for SIMBRINZA has not been studied, the IOP-lowering effect of brinzolamide is expected to last for 5-7 days.
Croatian: Iako učinak SIMBRINZE na trajanje sniženja IOT-a nije ispitivan, očekivani učinak brinzolamida na smanjenje IOT-a je 5-7 dana.
English: In contrast, brimonidine exhibits linear pharmacokinetics over the clinically therapeutic dose range.
Croatian: Nasuprot tome, farmakokinetika brimonidina je linearna u rasponu kliničkih terapijskih doza.
English: Serum electrolyte levels (particularly potassium) and blood pH levels must be monitored.
Croatian: Mora se pratiti razina elektrolita u serumu (posebice kalija) i pH krvi.
English: Brimonidine tartrate may cause ocular allergic reactions.
Croatian: Brimonidintartarat može uzrokovati okularne alergijske reakcije.
English: Use in adults, including the elderly The recommended dose is one drop of SIMBRINZA in the affected eye(s) two times daily.
Croatian: Primjena kod odraslih, uključujući starije osobe Preporučena doza je jedna kap SIMBRINZE u oboljelo oko (oči) dva puta dnevno.
English: Do not stop using SIMBRINZA without first speaking to your doctor.
Croatian: Nemojte prestati primjenjivati SIMBRINZU a da se prije ne posavjetujete s liječnikom.
English: Very rare: uveitis
Croatian: Vrlo rijetko: uveitis
English: Brinzolamide and Ndesethylbrinzolamide do not inhibit cytochrome P450 isozymes at concentrations at least 100-fold above maximum systemic levels.
Croatian: Brinzolamid i N-desetilbrinzolamid ne inhibiraju citrokrom P450 izozime kod koncentracija najmanje 100 puta većim od maksimalnih sistemskih razina.
English: Tiny amounts of hydrochloric acid and/or sodium hydroxide are added to keep acidity levels (pH levels) normal.
Croatian: Male količine kloridne kiseline i/ili natrijeva hidroksida dodane su radi održavanja normalne razine kiselosti (vrijednosti pH).
English: Tell your doctor, optometrist (optician) or pharmacist if you are using, have recently used, or might use any other medicines.
Croatian: Obavijestite svog liječnika, optometristu (optičara) ili ljekarnika ako primjenjujete, nedavno ste primijenili ili biste mogli primijeniti bilo koje druge lijekove.
English: Patients should be instructed to keep the bottle tightly closed when not in use.
Croatian: Preporučite bolesniku da bocu drži dobro zatvorenom kada se ne koristi.
English: Neonates and infants under the age of 2 years (see section 4.4).
Croatian: Novorođenčad i dojenčad ispod 2 godine starosti (vidjeti dio 4.4).
English: Brinzolamide was not teratogenic in rats and rabbits, following systemic administration (oral gavage).
Croatian: Brinzolamid nije bio teratogen kod štakora i kunića nakon sistemske primjene (oralna gavaža).
English: Caution is advised when initiating (or changing the dose of) concomitant systemic medicinal products (irrespective of pharmaceutical form) which may interact with α-adrenergic agonists or interfere with their activity, i.e. agonists or antagonists of the adrenergic receptor (e.g. isoprenaline, prazosin).
Croatian: Savjetuje se oprez pri istodobnom uvođenju (ili promjeni doze) sistemskih lijekova (bez obzira na njihov farmaceutski oblik) koji mogu stupati u interakcije s α-adrenergičkim agonistima ili utjecati na njihovu aktivnost, odnosno s agonistima ili antagonistima adrenergičkih receptora (npr. izoprenalin, prazosin).
English: Manufacturer Alcon Cusí, S.A. Camil Fabra 58 08320 El Masnou Spain
Croatian: Proizvođač Alcon Cusí, S.A. Camil Fabra 58 08320 El Masnou Španjolska
English: You may find that your vision is blurred or abnormal for a time just after using SIMBRINZA.
Croatian: Može Vam se dogoditi da Vam je vid zamagljen ili poremećen neko vrijeme nakon primjene SIMBRINZE.
English: It was reported that the hypotensive episode was followed by rebound hypertension.
Croatian: Prijavljena je kao hipotenzivna epizoda nakon koje je uslijedila povratna hipertenzija.
English: Manufacturer Alcon-Couvreur N.V. Rijksweg 14
Croatian: Proizvođač Alcon-Couvreur N.V. Rijksweg 14
English: Although both brinzolamide and brimonidine lower IOP by suppressing aqueous humour formation, their mechanisms of action are different.
Croatian: Iako i brinzolamid i brimonidin snižavaju IOT suprimirajući stvaranje očne vodice, njihov mehanizam djelovanja je različit.
English: Non-clinical data do not show any effects of brinzolamide or brimonidine on fertility.
Croatian: Neklinički podaci ne ukazuju na utjecaj brinzolamida ili brimonidina na plodnost.
English: However, clinical and non-clinical safety data show it to be welltolerated and safe during chronic administration.
Croatian: No klinički i neklinički podaci o sigurnosti primjene pokazuju da se dobro podnosi i da je neškodljiv pri kroničnoj primjeni.
English: Additionally, administration of brimonidine results in an increase in uveoscleral outflow.
Croatian: Dodatno, primjena brimonidina rezultira povećanjem uveoskleralnog otjecanja.
English: Oxidative cleavage of the imidazoline ring to 5-bromo-6-guanidinoquinoxaline is also observed.
Croatian: Primijećeno je i oksidativno cijepanje imidazolnog prstena u 5-bromo-6-gvanidinokinoksalin.
English: SIMBRINZA is therefore contraindicated in children below 2 years of age (see section 4.3).
Croatian: SIMBRINZA je stoga kontraindicirana u djece mlađe od 2 godine (vidjeti dio 4.3).
English: The European Medicines Agency has waived the obligation to submit the results of studies with SIMBRINZA in all subsets of the paediatric population in the treatment of glaucoma and ocular hypertension (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove izuzela je obvezu podnošenja rezultata ispitivanja SIMBRINZE u svim podskupinama pedijatrijske populacije u liječenju glaukoma i okularne hipertenzije (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Animal studies with oral brimonidine do not indicate direct harmful effects with respect to reproductive toxicity.
Croatian: U ispitivanjima na životinjama brimonidin primijenjen peroralno nije pokazao direktan štetan učinak vezan uz reproduktivnu toksičnost.
English: Tricyclic antidepressants may blunt the ocular hypotensive response of SIMBRINZA.
Croatian: Triciklički antidepresivi mogu oslabiti hipotenzivni okularni odgovor SIMBRINZE.
English: Pharmacotherapeutic group: Ophthalmologicals, Antiglaucoma preparations and miotics, ATC code: S01EC54
Croatian: Farmakoterapijska skupina: Oftalmici, Pripravci za liječenje glaukoma i miotici, ATK oznaka: S01EC54
English: • General side effects: fainting, increased blood pressure
Croatian: - Opće nuspojave: nesvjestica, povišeni krvni tlak
English: The use of brimonidine has been associated with minimal decreases in blood pressure.
Croatian: Primjena brimonidina povezana je s minimalnim sniženjem krvnog tlaka.
English: No data on the level of circulating catecholamines after SIMBRINZA administration are available.
Croatian: Nema dostupnih podataka o razini cirkulirajućih kateholamina nakon primjene SIMBRINZE.
English: To prevent contamination of the dropper tip and solution, care must be taken not to touch the eyelids, surrounding areas or other surfaces with the dropper tip of the bottle.
Croatian: Da bi se spriječila kontaminacija vrha kapaljke i otopine, potrebno je paziti da se vrhom kapaljke boce ne dotiču vjeđe, okolna područja ili druge površine.
English: During lactation, the no adverse effect level in the offspring was 5 mg/kg/day.
Croatian: Tijekom laktacije, doza pri kojoj nije bilo učinaka na mladunčad iznosila je 5 mg/kg/dan.
English: Tell your doctor if you are taking or intend to take any of the following medicines: - medicines to lower blood pressure - heart medicines including digoxin (used to treat heart conditions) - other medicines for glaucoma that also treat altitude sickness known as acetazolamide,
Croatian: Obavijestite svog liječnika ako uzimate ili planirate uzeti bilo koji od slijedećih lijekova: - lijekove za snižavanje krvnog tlaka - lijekove za srce uključujući digoksin (koriste se za liječenje srčanih poremećaja) - druge lijekove za glaukom, koji također liječe i visinsku bolest, a poznati su kao acetazolamid,
English: Uncommon: vertigo
Croatian: Manje često: vertigo
English: A study of brinzolamide in Japanese versus non-Japanese subjects showed similar systemic pharmacokinetics between the two groups.
Croatian: Ispitivanje brinzolamida u Japanaca u odnosu na druge ispitanike pokazala su da je sistemska farmakokinetika u obje skupine bila slična.
English: Hypersensitivity to sulphonamides (see section 4.4).
Croatian: Preosjetljivost na sulfonamide (vidjeti dio 4.4).
English: SIMBRINZA can be affected by alcohol.
Croatian: Alkohol može utjecati na SIMBRINZU.
English: Within each frequency-grouping, adverse reactions are presented in order of decreasing seriousness.
Croatian: Unutar svake skupine učestalosti, nuspojave su prikazane redom od ozbiljnijih prema manje ozbiljnima.
English: Brinzolamide belongs to a group of medicines called carbonic anhydrase inhibitors and brimonidine tartrate belongs to a group of medicines called alpha-2 adrenergic receptor agonists.
Croatian: Brinzolamid pripada skupini lijekova koji se nazivaju inhibitori karboanhidraze, a brimonidintartarat pripada skupini lijekova koji se nazivaju agonisti alfa-2-adrenergičkih receptora.