FrancophonIA/ELRC3.0 huggingface dataset:
English: If you inject too much NutropinAq over a long period of time (years), you may experience some overgrowth of parts of your body such as ears, nose, lips, tongue and cheekbone (gigantism and/or acromegaly).
Slovenian: Če ste uporabljali prevelik odmerek zdravila NutropinAq daljši čas (leta), se lahko pojavi določena prekomerna rast posameznih delov telesa, kot so ušesa, nos, ustnice, jezik in ličnice (gigantizem in/ali akromegalija).
English: Adults with growth hormone deficiency (n=127) Very common: paraesthesia.
Slovenian: Odrasli s pomanjkanjem rastnega hormona (n=127) Zelo pogosti: parestezija.
English: The recommended final dose seldom exceeds 1.0 mg/day.
Slovenian: Priporočeni končni odmerek redko presega 1,0 mg/dan.
English: If you attempt to dose more than 4 mg at a time, the medicine will either be forced out of the needle and wasted or excess pressure will be placed upon the cartridge and it may crack.
Slovenian: Če poskusite naenkrat injicirati več kot 4 mg, bo zdravilo bodisi steklo iz igle in šlo v nič bodisi bo vložek deležen prevelikega pritiska in lahko poči.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT
Slovenian: VSEBNOST IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ENOT
English: NutropinAq is a solution for injection (in a cartridge (10 mg/2 ml) - pack size of 1, 3 and 6).
Slovenian: Zdravilo NutropinAq je raztopina za injiciranje (v vložku (10 mg/2 ml) - pakiranja po 1, 3 in 6).
English: Then, start a new cartridge (as described in Part I) to administer the remaining portion of your medication.
Slovenian: V drugem primeru potem načnite nov vložek (kot je opisano v I. delu), da boste injicirali preostanek odmerka zdravila.
English: After removal from the refrigerator, if the solution is cloudy, the content must not be injected.
Slovenian: Če je raztopina, ko jo vzamete iz hladilnika, motna, vsebine ne smete injicirati.
English: • When your body does not make enough growth hormone and for this reason you are not growing properly.
Slovenian: • če telo ne tvori dovolj rastnega hormona in zato otrok ne raste pravilno.
English: Animal studies with somatropin showed that growth hormone localises to highly perfused organs, particularly the liver and kidney.
Slovenian: Študije na živalih s somatropinom so pokazale, da se rastni hormon lokalizira v močno prekrvljenih organih, posebno v jetrih in ledvicah.
English: Both studies demonstrated a statistically significant increase in growth rate compared to placebo over the first year (9.1-10.9 cm/year vs 6.2-6.6 cm/year), which decreased slightly in the second year (7.4-7.9 cm/year vs 5.5-6.6 cm/year).
Slovenian: Obe študiji sta pokazali statistično pomembno povečanje stopnje rasti v primerjavi s placebom v prvem letu (9,1-10,9 cm/leto v primerjavi s 6,2-6,6 cm/leto), ki se je nekoliko zmanjšala v drugem letu (7,4-7,9 cm/leto v primerjavi s 5,5-6,6 cm/leto).
English: The most serious adverse reactions from the pivotal and supportive clinical trials were neoplasm and intracranial hypertension.
Slovenian: Najresnejši neželeni učinki v ključnih in podpornih kliničnih preskušanjih so bile novotvorbe in intrakranialna hipertenzija.
English: It is typically associated with papilloedema, visual changes, headache, nausea, and/or vomiting and symptoms usually occur within eight weeks of initiation of therapy with NutropinAq.
Slovenian: Običajno je bila povezana s papiledemom, spremembami vida, glavobolom, navzeo in/ali bruhanjem, simptomi pa so se običajno pojavili v osmih tednih po uvedbi zdravljenja z zdravilom NutropinAq.
English: The final dose is rarely above 1.0 mg/day.
Slovenian: Končni odmerek je redko večji od 1,0 mg/dan.
English: The dose of NutropinAq to be injected will be decided by your doctor.
Slovenian: Odmerek zdravila NutropinAq, ki ga boste injicirali, bo določil zdravnik.
English: Girls with Turner syndrome commonly reported abnormally heavy bleeding at menstruation.
Slovenian: Pri deklicah s Turnerjevim sindromom so pogosto poročali o nenormalno močnih menstruacijskih krvavitvah.
English: Return the cartridge to your pharmacist or prescribing doctor.
Slovenian: Vložek vrnite svojemu farmacevtu ali zdravniku, ki ga je predpisal.
English: For subsequent injections with the NutropinAq Pen, attach a new needle, push the white reset button and dial your dose.
Slovenian: Za nadaljnje injekcije z injekcijskim peresnikom NutropinAq Pen namestite novo iglo, pritisnite beli nastavitveni gumb in nastavite svoj odmerek.
English: Wipe the rubber seal of the NutropinAq with rubbing alcohol or an antiseptic solution to prevent contamination of the contents by microorganisms that may be introduced by repeated needle insertions.
Slovenian: Obrišite gumijasto zaporo vložka zdravila NutropinAq z alkoholom ali antiseptično raztopino, da boste preprečili kontaminacijo vsebine z mikroorganizmi, do česar bi lahko prišlo zaradi večkratnega zabadanja injekcijske igle.
English: For each injection you should use a new sterile injection needle.
Slovenian: Pri vsakem injiciranju morate uporabiti novo sterilno injekcijsko iglo.
English: Girls with growth failure associated with Turner syndrome (n=108) Common: menorrhagia.
Slovenian: Deklice z zaostankom v rasti, povezanim s Turnerjevim sindromom (n=108) Pogosti: menoragija.
English: A: The NutropinAq Pen is designed to last 24 months from the time you first use your pen.
Slovenian: O: Injekcijski peresnik NutropinAq Pen je zasnovan tako, da se lahko uporablja 24 mesecev od prve uporabe.
English: NutropinAq is not indicated for the long-term treatment of paediatric patients who have growth failure due to genetically confirmed Prader-Willi syndrome, unless they also have a diagnosis of growth hormone deficiency.
Slovenian: Zdravilo NutropinAq ni indicirano za dolgotrajno zdravljenje pri pediatričnih bolnikih z zaostankom v rasti zaradi genetsko potrjenega Prader-Willijevega sindroma, razen če imajo ti bolniki tudi diagnozo pomanjkanja rastnega hormona.
English: • The NutropinAq cartridge may be used for up to 28 days.
Slovenian: • Vložek zdravila NutropinAq smete uporabljati največ 28 dni.
English: Reduced ability to absorb sugar (glucose) from your blood leading to high blood sugar levels (hyperglycemia).
Slovenian: Zmanjšana sposobnost za absorpcijo sladkorja (glukoze) iz krvi, kar vodi do visoke ravni krvnega sladkorja (hiperglikemija).
English: Acute overdose could lead to hyperglycaemia.
Slovenian: Akutno preveliko odmerjanje lahko povzroči hiperglikemijo.
English: Increased heart rate (tachycardia) and high blood pressure (hypertension).
Slovenian: Zvečan srčni utrip (tahikardija) in visok krvni tlak (hipertenzija).
English: No significant changes in bone mineral density (BMD) were observed in adult-onset AGHD patients, however in the childhood-onset study, all groups had an increase in BMD at 24 months, although there was no statistically significant dose response for total body BMD.
Slovenian: Pri odraslih bolnikih s pomanjkanjem rastnega hormona z začetkom v odrasli dobi niso opazili pomembnih sprememb mineralne gostote kosti (BMD- bone mineral density), v študiji z začetkom pomanjkanja v otroštvu pa so vse skupine imele večje BMD v 24. mesecu, čeprav ni bilo statistično pomembnega odziva na odmerek za BMD celotnega telesa.
English: Growth hormone is filtered at the glomerulus and reabsorbed in the proximal tubules.
Slovenian: Rastni hormon se filtrira v glomerulih in reabsorbira v proksimalnih tubulih.
English: What NutropinAq is and what it is used for
Slovenian: Kaj je zdravilo NutropinAq in za kaj ga uporabljamo
English: The effect of NutropinAq has not been assessed in conventional animal fertility studies (see section 5.3) or clinical studies.
Slovenian: Učinkov zdravila NutropinAq v običajnih študijah plodnosti pri živalih (glejte poglavje 5.3) ali v kliničnih študijah niso vrednotili.
English: Do not use this medicine after the expiry date which is stated on the label of the cartridge and the carton after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki na vložku in škatli poleg oznake “EXP” ali “Uporabno do”.
English: It is recombinant, meaning it is made outside of the body by a special process.
Slovenian: Somatropin je pridobljen z genskim inženirstvom, kar pomeni, da je s posebnim postopkom pridobljen zunaj telesa.
English: In adults, it helps to maintain normal body shape and metabolism for example lipid profile and glucose levels.
Slovenian: Pri odraslih zdravilo omogoča vzdrževati normalno obliko telesa in presnovo, na primer lipidni profil in vrednosti glukoze.
English: If no drop of medicine appears, push the white reset button again.
Slovenian: Če se kapljica zdravila ne pojavi, znova pritisnite beli nastavitveni gumb.
English: A: To maintain its strength.
Slovenian: O: Za ohranitev jakosti zdravila.
English: Animal studies suggest that the kidney is the dominant organ of clearance.
Slovenian: Študije na živalih kažejo, da so glavni organ izločanja ledvice.
English: Twist off the needle and discard it properly.
Slovenian: Iglo odvijte in jo pravilno zavrzite.
English: After subcutaneous bolus administration, the mean terminal half-life t½ of somatropin is about 2.3 hours.
Slovenian: Po subkutani bolusni aplikaciji je povprečni končni razpolovni čas t½ somatropina približno 2,3 ure.
English: In children with chronic renal insufficiency:
Slovenian: Otroci s kronično ledvično insuficienco:
English: In both studies, somatropin treatment resulted in significant changes compared to placebo in total body % fat (-6.3 to -3.6 vs +0.2 to-0.1), trunk % fat (-7.6 to -4.3 vs +0.6 to 0.0) and total body % lean (+3.6 to +6.4 vs -0.2 to +0.2).
Slovenian: V obeh študijah je pri zdravljenju s somatropinom prišlo do pomembnih sprememb v primerjavi s placebom v % skupnega telesnega maščevja (-6,3 do -3,6 v primerjavi z +0,2 do -0,1), % maščevja na trupu (-7,6 do -4,3 v primerjavi s +0,6 do 0.0) in % skupne puste telesne mase (+3,6 do +6,4 v primerjavi z -0,2 do +0,2).
English: Compared with matched historical controls, early somatropin therapy (mean duration of 5.6 years) combined with oestrogen replacement at age 12 years resulted in an adult height gain of 5.9 cm (n=26), whereas girls who initiated oestrogen at age 15 years (mean duration of somatropin therapy 6.1 years) had a mean adult height gain of 8.3 cm (n=29).
Slovenian: V primerjavi z ustreznimi historičnimi kontrolami, je bilo zgodnje zdravljenje s somatropinom (povprečno trajanje 5,6 let) v kombinaciji z nadomeščanjem estrogena pri starosti 12 let, povezano s pridobitvijo telesne višine v odrasli dobi za 5,9 cm (n=26), medtem ko so dekleta, ki so začela zdravljenje z estrogenom pri starosti 15 let (srednje trajanje zdravljenja s somatropinom 6,1 let), imele povprečni prirastek telesne višine v odrasli dobi 8,3 cm (n=29).
English: Toxicity to reproduction and development
Slovenian: Škodljivi vplivi na razmnoževanje in razvoj
English: Sensitive and dry skin (exfoliative dermatitis), changes in thickness of the skin, excessive growth of hair on the face and body (hirsutism), hives (urticaria).
Slovenian: Občutljiva in suha koža (eksfoliativni dermatitis), spremembe v debelini kože, prekomerna rast dlak na obrazu in telesu pri ženskah (hirzutizem) in koprivnica (urtikarija).
English: Tell your doctor immediately if you experience visual changes, bad or frequent headaches, associated with feeling sick (nausea) or vomiting.
Slovenian: Nemudoma obvestite svojega zdravnika, če opazite spremembe vida, hude ali pogoste glavobole, ki so povezani s siljenjem na bruhanje (navzea) ali z bruhanjem.
English: In total, 128 patients received somatropin over the 24 month controlled phase of the 2 studies, and 139 patients were treated with somatropin in the open extension phases.
Slovenian: V 24-mesečni nadzorovani fazi dveh študij je somatropin prejemalo 128 bolnikov, v odprti podaljšani fazi pa se je s somatropinom zdravilo 139 bolnikov.
English: NutropinAq therapy should be carried out under regular guidance of a doctor who is experienced in growth hormone deficiency.
Slovenian: Zdravljenje z zdravilom NutropinAq mora potekati pod rednim nadzorom zdravnika, ki ima izkušnje z zdravljenjem pomanjkanja rastnega hormona.
English: Test for growth hormone deficiency should not be performed until adequate replacement therapy for other hormone deficiencies have been instituted.
Slovenian: Preiskave za pomanjkanje rastnega hormona se ne sme opraviti pred začetkom ustreznega nadomestnega zdravljenja drugih hormonskih pomanjkanj.
English: Common: Drug specific antibody present
Slovenian: Pogosti: prisotnost specifičnih protiteles proti zdravilu
English: You have to inject NutropinAq every day under the skin (subcutaneous injection).
Slovenian: Zdravilo NutropinAq morate vsak dan injicirati pod kožo (subkutana injekcija).
English: - Long-term treatment of girls from 2 years old with growth failure associated with Turner syndrome.
Slovenian: - Dolgotrajno zdravljenje zaostanka v rasti pri deklicah, starejših od 2 let, povezanega s Turnerjevim sindromom.
English: Change the injection sites to avoid discomfort.
Slovenian: Mesta injiciranja krožno menjavajte, da boste preprečili neprijetnosti.
English: At the start of therapy, it is recommended that a doctor or a nurse give you the injection and train you with the NutropinAq Pen.
Slovenian: Na začetku zdravljenja je priporočljivo, da vam injekcijo da zdravnik ali medicinska sestra in vas nauči pravilne uporabe injekcijskega peresnika NutropinAq Pen.
English: For in-use storage conditions of the medicinal product, see section 6.3.
Slovenian: Za pogoje shranjevanja med uporabo zdravila glejte poglavje 6.3.
English: • If you notice a curve of your spine (scoliosis) you will need to be checked often by your doctor as scoliosis may progress in any child during rapid growth.
Slovenian: • Če opazite ukrivljenost hrbtenice (skolioza), bodo potrebni pogostejši pregledi pri zdravniku, saj lahko skolioza napreduje pri vsakem otroku v obdobju hitre rasti.
English: • If your body does not make enough growth hormone as an adult.
Slovenian: • če telo ne tvori dovolj rastnega hormona v odrasli dobi.
English: Reported values for half-lives for endogenous GH in normal adult black males are not different from observed values for normal adult white males.
Slovenian: Vrednosti razpolovnega časa endogenega rastnega hormona pri normalnih odraslih moških črne rase se ne razlikujejo od vrednosti pri normalnih odraslih moških bele rase.
English: Actions that have been demonstrated for human growth hormone include:
Slovenian: Med dokazanimi učinki humanega rastnega hormona so:
English: Other medicines and NutropinAq
Slovenian: Druga zdravila in zdravilo NutropinAq
English: Only use the pen needles recommended by your doctor or nurse.
Slovenian: Uporabljajte le tiste igle za injekcijski peresnik, ki vam jih svetuje zdravnik ali medicinska sestra.
English: After this training, you will be able to inject yourself or be injected by a trained care-giver.
Slovenian: Po ustreznem usposabljanju si lahko zdravilo injicirate sami ali pa vam ga injicira oseba, ki skrbi za vas.
English: Pull the needle shield off the pen (if you have used one) and place the larger needle cap on a flat surface.
Slovenian: Potegnite ščitnik igle iz injekcijskega peresnika (če ste ga uporabili) in položite večji pokrovček igle na ravno površino.
English: This side effect is rare, it may affect up to 1 in 1,000 patients.
Slovenian: Ta neželeni učinek je redek, pojavi se lahko pri do 1 od 1.000 bolnikov.
English: Inspect all new cartridges prior to use.
Slovenian: Vse nove vložke pred uporabo preglejte.
English: The underlying risk varies according to the underlying cause for growth hormone deficiency (e.g. secondary to intracranial lesion), associated co- morbidities and treatment(s) undertaken.
Slovenian: Osnovno tveganje se razlikuje glede na osnovni vzrok za pomanjkanje rastnega hormona (npr. sekundarno po intrakranialni leziji), povezavo s sočasnimi obolenji in zdravljenjem.
English: Limited published data indicate that growth hormone treatment increases cytochrome P450 mediated antipyrine clearance in man.
Slovenian: Omejeni objavljeni podatki kažejo, da zdravljenje z rastnim hormonom pri človeku zveča s citokromom P450 posredovani očistek antipirina.
English: • if you are treated with sex steroids, anticonvulsants or cyclosporin ask the doctor for advice.
Slovenian: • Če se zdravite s spolnimi steroidi, z antiepileptiki ali s ciklosporinom, se posvetujte s svojim zdravnikom.
English: If you have injected more NutropinAq than you should have, contact your doctor for advice.
Slovenian: Če ste si injicirali večji odmerek zdravila NutropinAq, kot bi smeli, se posvetujte s svojim zdravnikom.
English: In vitro and in vivo preclinical and clinical tests have demonstrated that somatropin is therapeutically equivalent to human growth hormone of pituitary origin.
Slovenian: Predklinične in klinične raziskave in vitro in in vivo so pokazale, da je somatropin terapevtsko enakovreden humanemu rastnemu hormonu hipofiznega izvora.
English: Pharmacotherapeutic group: Pituitary and hypothalamic hormones and analogues, Somatropin and analogues, ATC Code: H01 AC 01
Slovenian: Farmakoterapevtska skupina: Hipofizni in hipotalamični hormoni ter sorodne učinkovine, somatropin in sorodne učinkovine, oznaka ATC: H01AC01
English: If you have intracranial hypertension, your doctor may decide to temporarily reduce or discontinue NutropinAq therapy.
Slovenian: Če imate intrakranialno hipertenzijo, lahko zdravnik začasno zmanjša odmerek zdravila NutropinAq ali zdravljenje prekine.
English: If you inject too much NutropinAq, your blood sugar level may decrease and become too low and then rise too high (hyperglycaemia).
Slovenian: Če ste si injicirali prevelik odmerek zdravila NutropinAq, se lahko koncentracija krvnega sladkorja zmanjša in postane prenizka, nato pa prekomerno naraste (hiperglikemija).
English: • If you experience visual changes, bad or frequent headache, associated with feeling sick (nausea) or vomiting, especially at the start of treatment, tell your doctor immediately.
Slovenian: • Če opazite spremembe vida, imate hude ali pogoste glavobole, povezane s siljenjem na bruhanje (navzea) ali z bruhanjem, še posebej po uvedbi zdravljenja, o tem nemudoma obvestite svojega zdravnika.
English: As shown by the illustrations below, NutropinAq pen and cartridges are available in two designs (with or without additional yellow colour).
Slovenian: Injekcijski peresnik NutropinAq Pen in vložki so na voljo v dveh zunanjih podobah (z ali brez dodatne rumene barve), kot je prikazano spodaj.
English: During pregnancy, maternal somatropin will largely be replaced by placental growth hormone.
Slovenian: Med nosečnostjo placentni rastni hormon v glavnem nadomesti materin somatropin.
English: Rare: Gynaecomastia
Slovenian: Redki: ginekomastija
English: Now turn the black dose knob clockwise (See illustration) by one click (0.1mg).
Slovenian: Zdaj zasučite črni odmerni gumb v smeri urinega kazalca (glejte sliko) za en klik (0,1 mg).
English: Growth failure associated with chronic renal insufficiency
Slovenian: Zaostanek v rasti, povezan s kronično ledvično insuficienco
English: There is no antidote for somatropin overdose.
Slovenian: Antidota za primere prevelikega odmerjanja somatropina ni.
English: Serum calcium is not significantly altered by somatropin.
Slovenian: Kalcija v serumu somatropin ne spremeni bistveno.
English: Needles from other countries may not fit on your NutropinAq Pen.
Slovenian: Zgodi se lahko, da se igle iz drugih držav ne prilegajo vašemu injekcijskemu peresniku NutropinAq Pen.
English: Thus, the greatest improvement in adult height was observed in patients who received early GH treatment and oestrogen after age 14 years.
Slovenian: Tako je bilo največje izboljšanje telesne višine v odrasli dobi doseženo pri bolnicah, ki so se zgodaj začele zdraviti z rastnim hormonom, z estrogenom pa po 14. letu starosti.
English: Your doctor or nurse will recommend a needle that is appropriate for you.
Slovenian: Zdravnik ali medicinska sestra vam bosta svetovala za vas primerno iglo.
English: Monitoring is advisable when somatropin is administered in combination with medicinal products known to be metabolised by CYP450 liver enzymes, such as corticosteroids, sex steroids, anticonvulsants, and cyclosporin.
Slovenian: Med uporabo somatropina v kombinaciji z zdravili, za katera je znano, da se presnavljajo z jetrnimi encimi CYP450, kot na primer kortikosteroidi, spolni steroidi, antiepileptiki ali ciklosporin, je priporočljivo nadziranje.
English: In patients with severe liver dysfunction a reduction in somatropin clearance has been noted.
Slovenian: Pri bolnikih s hudo motenim delovanjem jeter so opazili zmanjšanje očistka somatropina.
English: Children with growth failure due to inadequate growth hormone secretion (n=236) Common: central nervous system neoplasm (2 patients experienced a recurrent medulloblastoma, 1 patient experienced a histiocytoma).
Slovenian: Otroci z zaostankom v rasti zaradi nezadostnega izločanja rastnega hormona (n=236) Pogosti: novotvorbe centralnega živčnega sistema (dva bolnika s ponovitvijo meduloblastoma, en bolnik s histiocitomom).
English: Growth failure associated with Turner syndrome
Slovenian: Zaostanek v rasti, povezan s Turnerjevim sindromom
English: Information about the pharmacokinetics of somatropin in elderly and paediatric populations, in different races or genders and in patients with renal or hepatic impairment is incomplete.
Slovenian: Podatki o farmakokinetiki somatropina pri starostnikih, pediatrični populaciji, različnih rasah ali spolih in bolnikih z okvaro ledvic ali jeter, so nepopolni.
English: Approximately 2.5 % of patients from the NCGS have experienced drug related adverse reactions.
Slovenian: V študiji NCGS so se neželeni učinki zdravila pojavili pri približno 2,5 % bolnikov.
English: The volume of distribution at steady state for somatropin in healthy adult males is about 50 ml/kg bodyweight, approximating the serum volume.
Slovenian: Volumen porazdelitve somatropina v stanju dinamičnega ravnovesja je pri zdravih odraslih moških okrog 50 ml/kg telesne mase in se približuje volumnu seruma.
English: After intravenous bolus administration of somatropin, the mean terminal half-life t½ or t½is about 20 minutes and the mean clearance is reported to be in the range of 116 - 174 ml/h/kg.
Slovenian: Po intravenski bolusni aplikaciji somatropina je povprečni končni razpolovni čas t½ oz. t½ približno 20 minut, povprečni očistek pa od 116 - 174 ml/uro/kg.
English: Decrease in the number of red blood cells in the blood (anaemia), decrease in blood sugar level (hypoglycaemia) and increase in phosphate levels (hyperphosphatemia).
Slovenian: Zmanjšanje števila rdečih krvnih celic (anemija), znižanje vrednosti krvnega sladkorja (hipoglikemija) in zvišanje vrednosti fosfatov (hiperfosfatemija).
English: Do not take a double dose to make up for a missed dose.
Slovenian: Ne uporabite dvojnega odmerka, če ste pozabili uporabiti prejšnji odmerek.
English: Patients with ACTH deficiency should have their glucocorticoid replacement therapy carefully adjusted to avoid any inhibitory effect on growth.
Slovenian: Pri bolnikih s pomanjkanjem ACTH je treba nadomestno zdravljenje z glukokortikoidi skrbno prilagoditi, da bi preprečili zaviralni učinek na rast.
English: België/Belgique/Belgien Luxembourg/Luxemburg Ipsen NV Guldensporenpark 87 B-9820 Merelbeke België /Belgique/Belgien Tél/Tel: + 32 - 9 - 243 96 00
Slovenian: België/Belgique/Belgien Luxembourg/Luxemburg Ipsen NV Guldensporenpark 87 B-9820 Merelbeke België /Belgique/Belgien
English: What you need to know before you use NutropinAq
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo NutropinAq
English: It is then cleaved within renal cells into its constituent amino acids, which return to the systemic circulation.
Slovenian: V ledvičnih celicah se nato razcepi v aminokisline, ki ga gradijo, te pa se vrnejo v sistemski obtok.