FrancophonIA/ELRC3.0 huggingface dataset:
English: - Hypersensitivity to the active substances or to any of the excipients listed in section 6.1, or other sulphonylureas or sulphonamides - Cardiac failure or history of cardiac failure (NYHA stages I to IV) - Current bladder cancer or a history of bladder cancer - Uninvestigated macroscopic haematuria - Hepatic impairment - Type 1 diabetes mellitus - Diabetic coma - Diabetic ketoacidosis - Severe renal function disorders (creatinine clearance < 30 ml/min) - Pregnancy - Breast-feeding (see section 4.6)
Slovenian: - preobčutljivosti na učinkovine ali katero koli pomožno snov, navedeno v poglavju 6.1 ali druge sulfonilsečnine ali sulfonamide - srčnemu popuščanju ali anamnezi srčnega popuščanja (klasifikacija NYHA, stadiji I do IV) - raku mehurja ali raku mehurja v anamnezi - neraziskani makroskopski hematuriji - okvari jeter - sladkorni bolezni tipa 1 - diabetični komi - diabetični ketoacidozi - hudih motnjah ledvičnega delovanja (očistek kreatinina < 30 ml/min) - nosečnosti - dojenju (glejte poglavje 4.6)
English: Your doctor will ask you to have blood tests periodically during treatment with Tandemact.
Slovenian: Zdravnik vam bo v času zdravljenja z zdravilom Tandemact naročil, da opravljate redne krvne preglede.
English: Women of childbearing potential / Contraception in males and females Tandemact is not recommended in women of childbearing potential not using contraception.
Slovenian: Zdravilo Tandemact se ne priporoča pri ženskah v rodni dobi, ki ne uporabljajo učinkovite kontracepcije.
English: When meals are taken at irregular hours or skipped altogether, treatment with Tandemact may lead to hypoglycaemia due to the sulphonylurea component.
Slovenian: Pri nerednih ali izpuščenih obrokih lahko zdravljenje z zdravilom Tandemact zaradi sulfonilsečnine povzroči hipoglikemijo.
English: not known not known rash2
Slovenian: neznana neznana srbenje2
English: What Tandemact contains - The active substances are pioglitazone and glimepiride.
Slovenian: Kaj vsebuje zdravilo Tandemact - Učinkovini sta pioglitazon in glimepirid.
English: Since glimepiride belongs to the chemical class of sulfonylurea medicinal products, caution should be used in patients with G6PD-deficiency and a non-sulfonylurea alternative should be considered.
Slovenian: Ker sodi glimepirid kemijsko v skupino zdravil, ki so derivati sulfonilsečnine, je potrebna pri bolnikih s pomanjkanjem G6PD previdnost.
English: Talk to your doctor or pharmacist before taking Tandemact (see also section 4) - if you have a problem with your heart.
Slovenian: Pred začetkom jemanja zdravila Tandemact se posvetujte z zdravnikom ali s farmacevtom (glejte tudi poglavje 4):
English: In clinical trials with pioglitazone the incidence of elevations of ALT greater than three times the upper limit of normal was equal to placebo but less than that seen in metformin or sulphonylurea comparator groups.
Slovenian: 10 V kliničnih preskušanjih pioglitazona je bila incidenca povišanih vrednosti ALT, višjih kot trikratna zgornja meja normalnih vrednosti, enaka kot pri placebu, vendar nižja kot v primerjalnih skupinah metformina ali sulfonilsečnine.
English: An increased incidence in bone fractures in women was seen in a pooled analysis of adverse reactions reports of bone fracture from randomised, controlled, double blind clinical trials (see section 4.8).
Slovenian: V skupni analizi neželenih učinkov zlomov kosti iz randomiziranih, kontroliranih, dvojno slepih kliničnih preskušanj (glejte poglavje 4.8).
English: If large quantities have been ingested, gastric lavage is indicated, followed by activated charcoal and sodium-sulphate.
Slovenian: V primeru zaužitja velikih količin, je indicirano izpiranje želodca, ki mu sledi zaužitje aktivnega oglja in natrijevega sulfata.
English: Glimepiride acts mainly by stimulating insulin release from pancreatic beta cells.
Slovenian: Glimepirid deluje predvsem s spodbujanjem izločanja insulina iz celic beta v pankreasu.
English: Hypoglycaemia (low blood sugar) has been reported uncommonly (may affect up to 1 in 100 people) in patients taking Tandemact.
Slovenian: O hipoglikemiji (nizka raven sladkorja v krvi) so poročali občasno (pri največ 1 od 100 bolnikov) pri bolnikih, ki jemljejo zdravilo Tandemact.
English: - headache - inflammation of the sinuses (sinusitis) - vertigo - abnormal vision - sweating - tiredness - difficulty sleeping (insomnia) - decreased blood sugar - sugar in urine - proteins in urine - increased appetite - increase of an enzyme called lactic dehydrogenase (LDH)
Slovenian: - znižan krvni sladkor - sladkor v urinu - beljakovine v urinu - povečan apetit - povišanje encima, ki se imenuje laktatna dehidrogenaza (LDH)
English: Sulphonylureas regulate insulin secretion by closing the ATP-sensitive potassium channel in the beta cell membrane.
Slovenian: Sulfonilsečnine uravnavajo izločanje insulina z zaprtjem za ATP odvisnih kalijevih kanalčkov v membrani celic beta.
English: phenylbutazone, azapropazone and oxyfenbutazone insulin and oral antidiabetic products metformin salicylates and p-amino-salicylic acid anabolic steroids and male sex hormones chloramphenicol clarithromycin coumarin anticoagulants disopyramide fenfluramine fibrates angiotensin-converting enzyme (ACE) inhibitors fluoxetine allopurinol sympatholytics cyclo-, tro- and iphosphamides sulphinpyrazone certain long-acting sulphonamides tetracyclines
Slovenian: fenilbutazon, azapropazon in oksifenbutazon insulin in peroralni antidiabetiki metformin salicilati in p-aminosalicilna kislina anabolni steroidi in moški spolni hormoni kloramfenikol klaritromicin kumarinski antikoagulansi dizopiramid fenfluramin fibrati zaviralci angiotenzinske konvertaze (zaviralci ACE) fluoksetin alopurinol simpatikolitiki ciklo-, tro- in ifosfamidi sulfinpirazon nekateri dolgo delujoči sulfonamidi tetracikilini zaviralci MAO kinolonski antibiotiki probenecid mikonazol pentoksifilin (velik parenteralen odmerek) tritokalin flukonazol
English: oestrogens and progestagens, saluretics, thiazide diuretics, thyroid stimulating agents, glucocorticoids, phenothiazine derivatives, chlorpromazine, adrenaline and sympathicomimetics, nicotinic acid (high doses) and nicotinic acid derivatives, laxatives (long-term use), phenytoin, diazoxide, glucagon, barbiturates and rifampicin.
Slovenian: estrogeni in progestageni, saluretiki, tiazidni diuretiki, sredstva, ki stimulirajo ščitnico, glukokortikoidi, fenotiazinski derivati, klorpromazin, adrenalin in simpatikomimetiki, nikotinska kislina (veliki odmerki) in derivati nikotinske kisline, odvajala (dolgotrajna uporaba), fenitoin, diazoksid, glukagon, barbiturati in rifampicin acetozolamid
English: Therapy with Tandemact should not be initiated in patients with increased baseline liver enzyme levels (ALT > 2.5 x upper limit of normal) or with any other evidence of liver disease.
Slovenian: Pri bolnikih s povišanimi izhodiščnimi vrednostmi jetrnih encimov (ALT > 2,5-kratna zgornja meja normalnih vrednosti) ali s kakršnimi koli drugimi znaki jetrne bolezni, zdravljenja z zdravilom Tandemact ne smemo začeti.
English: Blurred vision due to swelling (or fluid) at the back of the eye (macular oedema) has also been reported in patients taking Tandemact (frequency cannot be estimated from the available data).
Slovenian: Pri bolnikih, ki jemljejo zdravilo Tandemact so poročali tudi o zamegljenem vidu zaradi otekline (ali tekočine) v zadnjem delu očesa (makularni edem) (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti).
English: Treatment with Tandemact requires regular monitoring of glycaemic control.
Slovenian: Pri zdravljenju z zdravilom Tandemact je potrebno redno spremljati glikemični nadzor.
English: The bioavailability of glimepiride after oral administration is complete.
Slovenian: Biološka uporabnost glimepirida je po peroralnem dajanju popolna.
English: There have been rare reports of elevated liver enzymes and hepatocellular dysfunction during post-marketing experience with pioglitazone and glimepiride (see section 4.8).
Slovenian: Iz izkušenj v obdobju trženja pioglitazona in glimepirida so poročali o redkih primerih povišanja jetrnih encimov in hepatocelularne disfunkcije (glejte poglavje 4.8).
English: Thiazolidinediones act primarily by reducing insulin resistance and sulphonylureas primarily by inducing insulin release from pancreatic beta cells.
Slovenian: Tiazolidindioni primarno zmanjšujejo insulinsko rezistenco, primarni učinek sulfonilsečnin pa je spodbujanje sproščanja insulina iz beta celic v pankreasu.
English: The physiological response to acute physical exercise, reduction of insulin secretion, is still present under glimepiride.
Slovenian: Zmanjšanje izločanja insulina, ki je fiziološki odziv na akutno telesno obremenitev, se med zdravljenjem z glimepiridom ohrani.
English: This is because some medicines can weaken or strengthen the effect of Tandemact on the level of sugar in your blood.
Slovenian: Nekatera zdravila lahko zmanjšajo ali povečajo učinek zdravila Tandemact na raven sladkorja v krvi.
English: Tandemact contains lactose monohydrate
Slovenian: Tablete vsebujejo laktozo monohidrat.
English: - anabolic steroids (supporting muscle build up) or male sex hormone replacement therapy - fluoxetine, MAO-inhibitors (to treat depression) - angiotensin-converting enzyme (ACE) inhibitors, sympatholytics, disopyramide, pentoxifylline,
Slovenian: klaritromicin (za zdravljenje bakterijskih ali glivičnih okužb) - anabolični steroidi (podpirajo izgradnjo mišic) ali nadomestna terapija z moškimi spolnimi hormoni - fluoksetin, zaviralci MAO (za zdravljenje depresije) - zaviralci angiotenzinske konvertaze (zaviralci ACE), simpatolitiki, dizopiramid, pentoksifilin,
English: Bladder cancer has been experienced uncommonly (may affect up to 1 in 100 people) in patients taking Tandemact.
Slovenian: Rak sečnega mehurja se lahko pojavi občasno (pri največ 1 od 100 bolnikov) pri bolnikih, ki jemljejo zdravilo Tandemact.
English: Glimepiride is transferred to the placenta.
Slovenian: Glimepirid prehaja skozi placento.
English: There is no clinical trial experience of other oral anti-hyperglycaemic medicinal products added to treatment with Tandemact or concomitantly administered glimepiride and pioglitazone.
Slovenian: Kliničnih izkušenj z zdravilom Tandemact v kombinaciji z drugimi peroralnimi antihiperglikemičnimi zdravili ali s sočasnim jemanjem glimepirida in pioglitazona ni.
English: Blood glucose should be closely monitored.
Slovenian: Treba je skrbno nadzirati raven glukoze v krvi.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Tandemact 30 mg/2 mg tablets
Slovenian: KAKOVOSTNA IN KOLIČINSKA SESTAVA Tandemact 30 mg/2 mg tablete
English: The symptoms may include cold sweat, tiredness, headache, rapid heartbeat, hunger pangs, irritability, nervousness or nausea.
Slovenian: Simptomi lahko vključujejo hladno znojenje, utrujenost, glavobol, hitro bitje srca, občutek lakote, razdražljivost, živčnost ali siljenje na bruhanje.
English: Allergic reactions have been reported with frequency not known (cannot be estimated from the available data) in patients taking Tandemact.
Slovenian: Pri bolnikih, ki jemljejo zdravilo Tandemact, so poročali o alergijskih reakcijah z neznano pogostnostju (iz razpoložljivih podatkov je ni mogoče oceniti).
English: 4.7 Effects on ability to drive and use machines Tandemact has minor influence on the ability to drive and use machines.
Slovenian: Zdravilo Tandemact ima blag vpliv na sposobnost vožnje in upravljanja s stroji.
English: Each tablet contains approximately 177 mg lactose monohydrate (see section 4.4).
Slovenian: Ena tableta vsebuje približno 177 mg laktoze monohidrata (glejte poglavje 4.4).
English: Some patients experienced the following side effects whilst taking pioglitazone and sulphonylureas, including glimepiride:
Slovenian: Nekateri bolniki med jemanjem pioglitazona in sulfonilsečnin, vključno z glimepiridom, izkusijo naslednje neželene učinke:
English: Co-administration of pioglitazone with rifampicin (an inducer of cytochrome P450 2C8) is reported to result in a 54% decrease in AUC of pioglitazone.
Slovenian: Poročali so, da sočasno dajanje pioglitazona z rifampicinom (induktor citokroma P450 2C8) povzroči 54% zmanjšanje AUC pioglitazona.
English: There have been post-marketing cases of cardiac failure reported when pioglitazone was used in combination with insulin or in patients with a history of cardiac failure.
Slovenian: V obdobju trženja zdravila so poročali o primerih srčnega popuščanja, ko so pioglitazon uporabljali v kombinaciji z insulinom ali pri bolnikih z anamnezo srčnega popuščanja.
English: Each tablet contains approximately 214 mg lactose monohydrate (see section 4.4).
Slovenian: Ena tableta vsebuje približno 214 mg laktoze monohidrata (glejte poglavje 4.4).
English: If you experience any of these, talk to your doctor as soon as possible.
Slovenian: Če opazite kar koli od naštetega, se čim prej posvetujte s svojim zdravnikom.
English: Glimepiride inhibits the glucose production in the liver by increasing the intracellular concentration of fructose-2,6-bisphosphate, which in turn inhibits the gluconeogenesis.
Slovenian: Glimepirid poveča znotrajcelično koncentracijo fruktoza-2,6-bisfosfata, kar zavira glukoneogenezo in zato s tem zavira glukoneogenezo.
English: Tandemact 45 mg/4 mg tablets
Slovenian: Tandemact 45 mg/4 mg tablete
English: Each tablet contains approximately 125 mg lactose monohydrate (see section 4.4).
Slovenian: Ena tableta vsebuje približno 125 mg laktoze monohidrata (glejte poglavje 4.4).
English: Metabolism and nutrition disorders hypoglycaemia uncommon appetite increased uncommon
Slovenian: Presnovne in prehranske motnje Hipoglikemija občasni povečan apetit občasni
English: Tandemact 30 mg/2 mg tablets Tandemact 30 mg/4 mg tablets Tandemact 45 mg/4 mg tablets pioglitazone/glimepiride
Slovenian: Tandemact 30 mg/2 mg tablete Tandemact 30 mg/4 mg tablete Tandemact 45 mg/4 mg tablete pioglitazon/glimepirid
English: Infections and infestations upper respiratory tract infection common common sinusitis uncommon uncommon
Slovenian: Infekcije in parazitske bolezni infekcije zgornjega respiratornega trakta pogosti pogosti
English: The symptoms may include cold sweat, tiredness, headache, rapid heartbeat, hunger pangs, irritability, nervousness, nausea, coma or convulsion.
Slovenian: Simptomi so lahko hladno znojenje, utrujenost, glavobol, hitro bitje srca, občutek lakote, razdražljivost, živčnost, siljenje na bruhanje, koma ali krči.
English: Renal elimination of the two metabolites was impaired.
Slovenian: Poslabšalo se je ledvično izločanje dveh presnovkov.
English: The following medicines can increase the blood sugar lowering effect of Tandemact.
Slovenian: Naslednja zdravila lahko povečajo učinek zdravila Tandemact na zniževanje ravni sladkorja v krvi.
English: Do not take Tandemact: - if you are allergic to pioglitazone, glimepiride, other sulphonylureas or sulphonamides, or any of the other ingredients of this medicine (listed in section 6) - if you have heart failure or have had heart failure in the past - if you have liver disease - if you have diabetic ketoacidosis (a complication of diabetes with rapid weight loss, nausea or vomiting) - if you have severe problems with your kidneys - if you have or have ever had bladder cancer - if you have blood in your urine that your doctor has not checked - if you have insulin dependent diabetes (type 1) - if you are in a diabetic coma - if you are pregnant - if you are breast-feeding
Slovenian: Ne jemljite zdravila Tandemact: - če ste alergični na pioglitazon, glimepirid, druge sulfonilsečnine ali sulfonamide ali katero koli sestavino tega zdravila (navedeno v poglavju 6) - če imate srčno popuščanje ali ste imeli srčno popuščanje v preteklosti - če imate obolenje jeter - če imate diabetično ketoacidozo (zaplet sladkorne bolezni z naglo izgubo telesne mase,
English: The following medicines may decrease the blood sugar lowering effect of Tandemact.
Slovenian: Naslednja zdravila lahko zmanjšajo učinek zdravila Tandemact na zniževanje ravni sladkorja v krvi.
English: These are in general reversible upon discontinuation of treatment.
Slovenian: Po prekinitvi zdravljenja so ta stanja ponavadi reverzibilna.
English: - allergic reactions including allergic shock - feeling sick (nausea), vomiting and diarrhoea - stomach ache - abdominal pressure - feeling of fullness in the stomach - sensitivity to light - decrease in salt (sodium) concentrations in the blood
Slovenian: Zelo redki (pojavijo se lahko pri največ 1 od 10.000 bolnikov) - bolezen jeter - alergijske reakcije, vključno z alergijskim šokom - siljenje na bruhanje (navzea), bruhanje in driska - bolečine v trebuhu - tiščanje v trebuhu - občutek polnosti v želodcu - občutljivost na svetlobo - zmanjšanje koncentracije soli (natrija) v krvi
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Tandemact.
Slovenian: Zdravilo Tandemact vsebuje laktozo monohidrat Če vam je zdravnik povedal, da imate intoleranco za nekatere sladkorje, se pred uporabo zdravila Tandemact posvetujte s svojim zdravnikom.
English: INFORMATION IN BRAILLE Tandemact 45 mg/4 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Tandemact 45 mg/4 mg
English: EU/1/06/366/005 EU/1/06/366/006 EU/1/06/366/007 EU/1/06/366/008 EU/1/06/366/009 EU/1/06/366/010 EU/1/06/366/011 EU/1/06/366/012 EU/1/06/366/013 EU/1/06/366/014 EU/1/06/366/015 EU/1/06/366/016 EU/1/06/366/017
Slovenian: EU/1/06/366/005 EU/1/06/366/006 EU/1/06/366/007 EU/1/06/366/008 EU/1/06/366/009 EU/1/06/366/010 EU/1/06/366/011 EU/1/06/366/012 EU/1/06/366/013 EU/1/06/366/014 EU/1/06/366/015 EU/1/06/366/016 EU/1/06/366/017 EU/1/06/366/018 EU/1/06/366/019 EU/1/06/366/020 EU/1/06/366/021 EU/1/06/366/022
English: It is used in adults when metformin is not suitable to treat type 2 (non-insulin dependent) diabetes mellitus.
Slovenian: Je zdravilo za zdravljenje sladkorne bolezni tipa 2 (od insulina neodvisne sladkorne bolezni) pri odraslih, ko metformin ni primeren.
English: Tandemact 30 mg/4 mg tablets
Slovenian: Tandemact 30 mg/4 mg tablete
English: INFORMATION IN BRAILLE Tandemact 30 mg/2 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Tandemact 30 mg/2 mg
English: In general observation in hospital is recommended.
Slovenian: Zaradi tega je ustrezen ukrep hospitalizacija.
English: Under the influence of sympatholytic active substances such as betablockers, clonidine, guanethidine and reserpine, the signs of adrenergic counterregulation to hypoglycaemia may be reduced or absent.
Slovenian: Znaki adrenergične protiregulacije na hipoglikemijo se lahko pod vplivom simpatikolitičnih učinkovin kot so zaviralci beta, klonidin, gvanetidin in reserpin, zmanjšajo ali izginejo.
English: If a pregnancy occurs, treatment with Tandemact should be discontinued.
Slovenian: Če se pojavi poslabšanje stanja srca, je treba zdravljenje z zdravilom Tandemact prekiniti.
English: How to store Tandemact
Slovenian: Shranjevanje zdravila Tandemact
English: Your blood sugar will be checked, and your dose of Tandemact may need to be changed.
Slovenian: Odmerek zdravila Tandemact bo morda treba spremeniti.
English: Gastrointestinal disorders5 flatulence common vomiting very rare very rare diarrhoea very rare very rare nausea very rare very rare abdominal pain very rare very rare abdominal pressure very rare very rare
Slovenian: Navzea zelo redki zelo redki bolečine v trebuhu zelo redki zelo redki napetost v trebuhu zelo redki zelo redki občutek polnosti v trebuhu zelo redki zelo redki
English: INFORMATION IN BRAILLE Tandemact 30 mg/4 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Tandemact 30 mg/4 mg
English: What Tandemact looks like and contents of the pack - Tandemact 30 mg/2 mg tablets are white to off-white, round, convex and debossed ‘4833 G' on one face and ‘30/2' on the other.
Slovenian: Izgled zdravila Tandemact in vsebina pakiranja Tablete Tandemact 30 mg/2 mg so bele do sivobele barve, okrogle, izbočene, z oznako ‘4833 G' na eni in ‘30/2' na drugi strani.
English: Weakening of the blood-glucose-lowering effect and, thus raised blood glucose levels may occur when one of the following active substances is taken, for example:
Slovenian: Ob jemanju katere izmed naslednjih učinkovin se lahko poveča učinek na znižanje koncentracije glukoze v krvi, zato lahko v nekaterih primerih pride do hipoglikemije:
English: Marketing authorisation holder Takeda Pharma A/S Dybendal Alle 10
Slovenian: Imetnik dovoljenja za promet z zdravilom Takeda Pharma A/S
English: This can lead to a risk of hyperglycaemia (high blood sugar level): - oestrogens, progestogens (female sex hormones) - thiazide diuretics and saluretics also called water tablets (to treat high blood pressure) - levothyroxine (to stimulate the thyroid gland) - glucocorticoids (to treat allergies and inflammation) - chlorpromazine and other phenothiazine derivatives (to treat severe mental disorders) - adrenaline and sympathicomimetics (to increase heart beat, to treat asthma or nasal congestion,
Slovenian: To lahko povzroči tveganje za hiperglikemijo (visoka raven sladkorja v krvi): - estrogeni, progestogeni (ženski spolni hormoni) - tiazidni diuretiki in saluretiki imenovani tudi zdravila za odvajanje vode (za zdravljenje visokega krvnega tlaka) - levotiroksin (za spodbujanje ščitnice) - glukokortikoidi (za zdravljenje alergij in vnetja) - klorpromazin in drugi fenotiazinski derivati (za zdravljenje hudih duševnih motenj) - adrenalin in simpatikomimetiki (za zvišanje srčnega utripa, za zdravljenje astme ali zamašenega nosu, kašlja in prehlada ali se uporabljajo v življenje-ogrožujočih nujnih primerih) - nikotinska kislina (za zdravljenje zvišane ravni holesterola) - dolgotrajna uporaba odvajal (za zdravljenje zaprtja) - fenitoin (za zdravljenje krčev) - barbiturati (za zdravljenje živčnost in težav s spanjem) - acetazolamid (za zdravljenje povišanega tlaka v očesu, ki se imenuje tudi glavkom) - diazoksid (za zdravljenje visokega krvnega tlaka ali nizke ravni sladkorja v krvi) - rifampicin (za zdravljenje okužb, tuberkuloze) - glukagon (za zdravljenje zelo nizkih ravni sladkorja v krvi)
English: If you experience this side effect, talk to your doctor as soon as possible.
Slovenian: Če izkusite ta neželeni učinek, se čim prej posvetujte s svojim zdravnikom.
English: Each Tandemact 45 mg/4 mg tablet contains 45 mg pioglitazone (as hydrochloride) and 4 mg glimepiride.
Slovenian: - Ena Tandemact 45 mg/4 mg tableta vsebuje 45 mg pioglitazona (v obliki pioglitazonijevega klorida) in 4 mg glimepirida.
English: The tablets contain lactose monohydrate and therefore should not be administered to patients with rare hereditary problems of galactose intolerance, the total lactase deficiency or glucose-galactose malabsorption.
Slovenian: Bolniki z redko dedno intoleranco za galaktozo, odsotnostjo encima laktaze ali malabsorpcijo glukoze/galaktoze ne smejo jemati tega zdravila.
English: Potentiation of the blood-glucose-lowering effect and, thus, in some instances hypoglycaemia may occur when one of the following active substances is taken, for example:
Slovenian: Ob jemanju katere izmed naslednjih učinkovin se lahko zmanjša učinek na znižanje koncentracije glukoze v krvi, zato lahko v nekaterih primerih pride do hiperglikemije:
English: Alertness and reaction time may be impaired due to low or high blood sugar due to glimepiride, especially when beginning or after altering treatment, or when Tandemact is not taken regularly.
Slovenian: Na začetku ali pri spremembi zdravljenja ali ob nerednem jemanju zdravila Tandemact se lahko poslabša budnost in odzivni čas zaradi nizke ali visoke ravni sladkorja v krvi, ki jo povzroča glimepirid.
English: A decrease in the dose of pioglitazone may be needed when gemfibrozil is concomitantly administered.
Slovenian: Ob sočasnem dajanju gemfibrozila bo morda treba znižati odmerek pioglitazona.
English: Localised swelling (oedema) has also been experienced commonly (may affect up to 1 in 10 people) in patients taking Tandemact in combination with insulin.
Slovenian: Bolniki ki jemljejo zdravilo Tandemact skupaj z insulinom so pogosto (pri največ 1 od 10 bolnikov) izkusili lokalizirano oteklino (edem).
English: NAME OF THE MEDICINAL PRODUCT Tandemact 45 mg/4 mg tablets pioglitazone/glimepiride
Slovenian: IME ZDRAVILA Tandemact 45 mg/4 mg tablete pioglitazon/glimepirid