FrancophonIA/ELRC3.0 huggingface dataset:
English: Zyclara is indicated for the topical treatment of clinically typical, nonhyperkeratotic, nonhypertrophic, visible or palpable actinic keratosis (AK) of the full face or balding scalp in immunocompetent adults when other topical treatment options are contraindicated or less appropriate.
Slovenian: Zdravilo Zyclara je indicirano za lokalno zdravljenje klinično značilnih, nehiperkeratoznih, nehipertrofičnih, vidnih ali otipljivih aktiničnih keratoz (AK) na celotnem obrazu ali na neporaščenem lasišču pri odraslih z normalno delujočim imunskim sistemom, kadar so drugi načini lokalnega zdravljenja kontraindicirani ali manj primerni.
English: The safety and efficacy of imiquimod in actinic keratosis in children and adolescents below the age of 18 years have not been established.
Slovenian: Pediatrična populacija Varnost in učinkovitost imikvimoda pri aktinični keratozi pri otrocih in mladostnikih, starih do 18 let,
English: Imiquimod cream therapy is not recommended until the skin has healed after any previous medicinal products or surgical treatment.
Slovenian: Uporaba imikvimod kreme ni priporočena, dokler se koža po predhodnem zdravljenju ali kirurškem posegu ne zaceli.
English: Avoid the concomitant use of Zyclara and any other imiquimod cream in the same treatment area.
Slovenian: Izogibajte se sočasni uporabi zdravila Zyclara s katero koli drugo kremo z imikvimodom na istem predelu zdravljenja.
English: In clinical trials most patients (159/160) using Zyclara for the treatment of AK experience local skin reactions (most frequently erythema, scab, and exfoliation/application site dryness) at the application site.
Slovenian: V kliničnih študijah je imela večina bolnikov (159/160), ki je uporabljala zdravilo Zyclara za zdravljenje AK, lokalne kožne reakcije (najpogosteje eritem, kraste in luščenje/suhost na mestu aplikacije) na mestu nanašanja.
English: Sachets should not be re-used once opened.
Slovenian: Ko so vrečice enkrat odprte, se ne smejo ponovno uporabiti.
English: Clinical studies investigating the use of imiquimod 5% cream for the treatment of actinic keratosis have detected a 0.4% (5/1214) frequency of alopecia at the treatment site or surrounding area.
Slovenian: Klinične študije, v katerih so preučevali uporabo imikvimod 5 % kreme za zdravljenje aktinične keratoze, so ugotovile 0,4 % (5/1214) pogostnost pojava alopecije na zdravljenem predelu ali v njegovi okolici.
English: They can be flat and scaly, or raised, rough, hard and warty.
Slovenian: Lahko so ravne in luskaste ali privzdignjene, hrapave, trde in bradavičaste.
English: Local skin reactions in the treatment area are in part anticipated and common due to its mode of action (see section 4.4).
Slovenian: Lokalne kožne reakcije na zdravljenem predelu so do neke mere pričakovane in so zaradi načina delovanja imikvimoda pogoste (glejte poglavje 4.4).
English: The intensity of the local skin reactions tend to be lower in the second cycle than in the first treatment cycle with Zyclara.
Slovenian: Zdi se, da je intenzivnost lokalnih kožnih reakcij v drugem ciklusu zdravljenja nižja kot v prvem ciklusu zdravljenja z zdravilom Zyclara.
English: Each gram of cream contains 37.5 mg of imiquimod.
Slovenian: En gram kreme vsebuje 37,5 mg imikvimoda.
English: Benzyl alcohol may cause allergic reactions and mild local irritation.
Slovenian: Benzil alkohol lahko povzroči alergične reakcije in blago lokalno draženje.
English: 170 09 Solna Sweden
Slovenian: 170 09 Solna Švedska
English: Re-treatment
Slovenian: Ponovno zdravljenje
English: The prescriber should demonstrate the proper application technique to the patient to maximise the benefit of Zyclara therapy.
Slovenian: Predpisovalec zdravila mora bolniku pokazati pravilno tehniko nanašanja kreme, da bi bil učinek zdravljenja z zdravilom Zyclara čim večji.
English: Before applying the cream, the patient should wash the treatment area with mild soap and water and allow the area to dry thoroughly.
Slovenian: Pred nanašanjem kreme mora bolnik zdravljeni predel umiti z blagim milom in vodo ter ga nato dobro osušiti.
English: Concomitant use of Zyclara and any other imiquimod creams in the same treatment area should be avoided since they contain the same active ingredient (imiquimod) and may increase the risk for and severity of local skin reactions.
Slovenian: Sočasni uporabi zdravila Zyclara in drugih krem z imikvimodom na istem zdravljenem predelu se je treba izogibati, saj vsebujeta enako učinkovino (imikvimod), kar lahko poveča tveganje za pojav in večjo izrazitost lokalnih kožnih reakcij.
English: Increases in systemic levels of alpha interferon and other cytokines following topical application of imiquimod were also observed in human data.
Slovenian: Zvišanje sistemskih ravni alfa interferona in drugih citokinov po lokalnem nanosu imikvimoda so opazili tudi pri ljudeh.
English: This medicine should not be applied to areas larger than either the full face or balding scalp.
Slovenian: Tega zdravila ne nanašajte na predele, katerih površina je večja kot npr. celoten obraz ali neporaščeno lasišče.
English: This medicine should only be used for actinic keratosis on the face and scalp.
Slovenian: To zdravilo se sme uporabljati samo za zdravljenje aktiničnih keratoz na obrazu in lasišču.
English: Each treatment cycle should last no longer than two weeks, even if you have missed doses.
Slovenian: Posamezen ciklus zdravljenja ne sme biti daljši od dveh tednov, tudi če ste pozabili uporabiti odmerke.
English: Before going to bed, wash your hands and the treatment area carefully with mild soap and water.
Slovenian: Preden se odpravite spat, si umijte roke in zdravljeni predel z blagim milom in vodo.
English: These studies showed that imiquimod was better than topical diclofenac in preventing the histological progression of AK lesions to in-situ or invasive squamous cell carcinoma (SCC).
Slovenian: Te študije so pokazale, da je imikvimod bolje preprečeval histološko napredovanje AK lezij v in situ ali invazivni ploščatocelični karcinom (SCC) kot lokalni diklofenak.
English: During therapy and until healed, affected skin is likely to appear noticeably different from normal skin.
Slovenian: Med zdravljenjem in do ozdravitve je prizadeta koža zelo verjetno videti opazno drugačna od zdrave kože.
English: The treatment area should not be bandaged or otherwise occluded.
Slovenian: Zdravljenega predela se ne sme prevezovati ali kako drugače prekriti.
English: When any skin reaction has gone you may then continue with your treatment in the recommended regular schedule.
Slovenian: Ko izginejo morebitne kožne reakcije, lahko nadaljujete z zdravljenjem po običajnem urniku.
English: Lesions clinically atypical for AK or suspicious for malignancy should be biopsied to determine appropriate treatment.
Slovenian: Pri lezijah, ki so atipične za AK, ali pri sumu na malignost, je potrebno opraviti biopsijo, da se določi primerno zdravljenje.
English: Interactions with systemic medicinal products would be limited by the minimal percutaneous absorption of imiquimod cream.
Slovenian: Interakcije s sistemskimi zdravili bi bile omejene zaradi minimalne absorpcije imikvimod kreme skozi kožo.
English: The cream should not be applied more than once daily.
Slovenian: Kreme se ne sme nanesti na kožo več kot enkrat na dan.
English: Due to its immunostimulating properties, imiquimod cream should be used with caution in patients who are receiving immunosuppressive medicinal products (see section 4.4).
Slovenian: Imikvimod kremo je treba zaradi njenih imunsko-stimulativnih lastnosti previdno uporabljati pri bolnikih, ki prejemajo imunosupresivna zdravila (glejte poglavje 4.4).
English: Local dermal irritation, especially at higher doses, was observed in both species.
Slovenian: Pri obeh vrstah so, predvsem pri večjih odmerkih, opazili lokalno draženje kože.
English: Treatment should be continued for the full treatment course even if all actinic keratosis appear to be gone.
Slovenian: Terapijo je treba nadaljevati celoten ciklus zdravljenja, tudi če so vse aktinične keratoze na videz izginile.
English: No overall differences in safety or effectiveness were observed between patients 65 years or older and the younger patients.
Slovenian: Med bolniki, starimi 65 let in več, ter mlajšimi bolniki niso opazili splošnih razlik glede varnosti in učinkovitosti.
English: This leaflet was last revised in (MM/YYYY).
Slovenian: Navodilo je bilo nazadnje revidirano dne MM/LLLL
English: Consideration should be given to balancing the benefit of imiquimod treatment for these patients with the risk associated either with the possibility of organ rejection or graft-versus-host disease or a possible worsening of their autoimmune condition.
Slovenian: Upoštevati je treba ravnovesje koristi zdravljenja z imikvimodom in tveganja, povezanega z možno zavrnitvijo presadka ali boleznijo presadka proti gostitelju (graft-versus-host disease) ali z možnim poslabšanjem avtoimunske bolezni.
English: The apparent half-life following topical dosing of 3.75% imiquimod cream in the pharmacokinetic study was calculated as approximately 29 hours.
Slovenian: Izračunana navidezna razpolovna doba po lokalnem odmerjanju 3,75 % imikvimod kreme v famrakokinetični študiji je bila približno 29 ur.
English: Information on re-treating actinic keratosis lesions that have cleared after two Zyclara treatment cycles of 2 weeks and subsequently recur is given in section 4.2 and 5.1.
Slovenian: Informacije o ponovnem zdravljenju lezij aktiničnih keratoz, ki so po dveh 2-tedenskih ciklih zdravljenja z zdravilom Zyclara izginile in se nato ponovno pojavile, so navedene v poglavjih 4.2 in
English: Do not use this medicine after the expiry date which is stated on the outer carton and the label after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na zunanji škatli in nalepki poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
English: Lesions that do not respond completely to treatment at 8 weeks after the second treatment cycle should be carefully re-evaluated and one additional 2-week treatment of Zyclara may be considered.
Slovenian: 8. tednu po drugem ciklusu zdravljenja na zdravljenje ne odzovejo popolnoma, je treba skrbno ponovno ovrednotiti in razmisliti o enem dodatnem 2-tedenskem zdravljenju z zdravilom Zyclara
English: Methyl parahydroxybenzoate (E 218) 2.0 mg/g cream Propyl parahydroxybenzoate (E 216) 0.2 mg/g cream Cetyl alcohol 22.0 mg/g cream Stearyl alcohol 31.0 mg/g cream Benzyl alcohol 20.0 mg/g cream
Slovenian: metilparahidroksibenzoat (E218) 2,0 mg/g kreme propilparahidroksibenzoat (E216) 0,2 mg/g kreme cetilalkohol 22,0 mg/g kreme stearilalkohol 31,0 mg/g kreme benzil alkohol 20,0 mg/g kreme
English: If you forget to use Zyclara
Slovenian: Če ste pozabili uporabiti zdravilo Zyclara
English: Squamous cell carcinoma (SCC) was reported in 1.3% (2/160) of patients treated with imiquimod 3.75%, in 0.6% (1/159) treated with vehicle.
Slovenian: O karcinomu skvamoznih celic so poročali pri 1,3 % (2/160) bolnikov, zdravljenih z imikvimodom 3,75 %, ter pri 0,6 % (1/159)
English: Your doctor will discuss if you should discontinue breastfeeding or discontinue Zyclara treatment.
Slovenian: Zdravnik se bo z vami pogovoril, ali naj prenehate dojiti ali prekiniti zdravljenje z zdravilom Zyclara.
English: Local skin reactions can be a sign that the medicine is working as intended.
Slovenian: Lokalna reakcija je lahko znak, da zdravilo deluje.
English: After about 8 hours, wash the area where Zyclara was applied with mild soap and water.
Slovenian: Po 8 urah področje nanosa zdravila Zyclara umijte z blagim milom in vodo.
English: • Do not use sunlamps or tanning-beds, and avoid exposure to sunlight as much as possible during treatment with this medicine.
Slovenian: - Med zdravljenjem s tem zdravilom ne uporabljajte svetilk za sončenje ali solarijev ter se izogibajte sončni svetlobi, kolikor je le mogoče.
English: Actinic keratosis lesions that have cleared after two Zyclara treatment cycles of 2 weeks and subsequently recur can be re-treated with one or two further Zyclara treatment cycles of 2 weeks following an at least 12 weeks treatment pause.
Slovenian: Aktinične keratoze, ki so po dveh 2-tedenskih ciklih zdravljenja z zdravilom Zyclara izginile in se nato ponovno pojavile, je mogoče ponovno zdraviti s še enim ali dodatnima dvema 2-tedenskima cikloma zdravljenja z zdravilom Zyclara, po najmanj 12-tedenskem premoru brez zdravljenja.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Zyclara in all subsets of the paediatric population in actinic keratosis (see section 4.2 for information on paediatric use).
Slovenian: Zyclara za vse podskupine pediatrične populacije pri aktinični keratozi (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Caution should be exercised when prescribing Zyclara to pregnant women.
Slovenian: Pri predpisovanju zdravila Zyclara nosečnicam je potrebna previdnost.
English: - Increase in liver enzymes There have been reports of increased liver enzymes.
Slovenian: Poročali so o povišanih vrednostih jetrnih encimov.
English: Furthermore, tumours were not seen at any site in a 2-year oral carcinogenicity study in rats.
Slovenian: Poleg tega se v dvoletni študiji kancerogenosti pri podganah pri peroralnem dajanju tumorji niso pojavili na nobenem mestu.
English: If you accidentally swallow this medicine please contact your doctor immediately.
Slovenian: Če ste pomotoma zaužili to zdravilo, nemudoma obvestite svojega zdravnika.
English: Boxes of 14, 28, and 56 single-use polyester/ white low density polyethylene/ aluminium foil sachets, containing 250 mg of cream.
Slovenian: Škatle po 14, 28 in 56 vrečic za enkratno uporabo iz poliesterske/bele z nizko gostoto polietilena/aluminijske folije, ki vsaka vsebuje 250 mg kreme.
English: Skin infection
Slovenian: Okužbe kože
English: Whilst using Zyclara and until healed, the treatment area is likely to appear noticeably different from normal skin.
Slovenian: Med zdravljenjem z zdravilom Zyclara in do dokončne ozdravitve bo zdravljeni predel najverjetneje izgledal opazno drugačno od običajne kože.
English: - Each box contains 14, 28 or 56 single-use polyester/ white low density polyethylene/aluminium foil sachets.
Slovenian: - Ena škatla vsebuje 14, 28 ali 56 vrečic za enkratno uporabo iz poliesterskega/belega polietilena z nizko gostoto/aluminijske folije.
English: Zyclara is for external use only.
Slovenian: Način uporabe Zdravilo Zyclara je primerno samo za zunanjo uporabo.
English: Up to 2 sachets of Zyclara may be applied to the treatment area (full face or scalp, but not both) at each daily application.
Slovenian: Na zdravljeni predel se lahko vsak dan naneseta do 2 vrečici zdravila Zyclara (celoten obraz ali lasišče, vendar ne oboje).
English: An interruption of dosing or dose adjustment should be considered (see section 4.8).
Slovenian: V takih primerih je treba razmisliti o prilagoditvi odmerka (glejte poglavje 4.8).
English: Local skin reactions are common but these reactions generally decrease in intensity during therapy or resolve after cessation of imiquimod cream therapy.
Slovenian: Lokalne kožne reakcije so pogoste, vendar se njihova intenzivnost med zdravljenjem navadno zmanjša oziroma po prekinitvi zdravljenja z imikvimod kremo izzvenijo.
English: It is unknown whether imiquimod/metabolites are excreted in human milk.
Slovenian: Ni znano, ali se imikvimod/presnovki izločajo v materino mleko.
English: If you stop using Zyclara
Slovenian: Če ste prenehali uporabljati zdravilo Zyclara
English: Use in immunocompromised patients and/or in patients with autoimmune conditions The safety and efficacy of Zyclara in immunocompromised patients (e.g. organ transplant patients) and/or patients with autoimmune conditions have not been established.
Slovenian: Varnost in učinkovitost zdravila Zyclara pri bolnikih z oslabljenim imunskim sistemom (npr. bolnikih s presajenimi organi) in/ali bolnikih z avtoimunskimi boleznimi nista bili ugotovljeni.
English: For the combined trials the complete clearance rate of the full face or balding scalp under imiquimod 3.75% cream was 35.6% (57/160 patients, CI 28.2%, 43.6 %) under vehicle 6.3% (10/159 patients, CI 3.1%, 11.3%) at the 8-week post-treatment visit.
Slovenian: V vseh preskušanjih je bila stopnja celotnega očistka 8 tednov po končanem zdravljenju po uporabi imikvomod 3,75 % kreme na področju celotnega obraza ali neporaščenega lasišča 35,6 % (57/160 bolnikov, interval zaupanja (IZ) 28,2 %, 43,6 %), po uporabi vehikla pa 6,3 % (10/159 bolnikov, IZ 3,1 %, 11,3 %).
English: If you have applied too much cream, wash the extra away with mild soap and water.
Slovenian: Če ste nanesli preveč kreme, sperite odvečno kremo z blagim milom in vodo.
English: Serious skin reactions (frequency not known) with skin lesions or spots on your skin that start out as small red areas and progress to look like mini targets, possibly with symptoms such as itching, fever, overall ill feeling, achy joints, vision problems, burning, painful or itchy eyes and mouth sores.
Slovenian: Hude kožne reakcije (neznana pogostnost) z lezijami ali drobne pike, ki se razvijejo v majhne rdeče lise, ki se lahko še naprej povečujejo in ki jih lahko spremljajo simptomi kot so srbenje, vročina, splošno slabo počutje, boleči sklepi, težave z vidom, pekoč občutek, boleče ali srbeče oči in razjede v ustih.
English: - The active substance is imiquimod.
Slovenian: - Učinkovina je imikvimod.
English: What Zyclara looks like and contents of the pack
Slovenian: Izgled zdravila Zyclara in vsebina pakiranja
English: - experience with imiquimod 5% cream
Slovenian: - izkušnje z uporabo imikvimod 5 % kreme.
English: In addition, release of cytokines was induced following dermal application and oral administration of imiquimod in various laboratory animals and in human studies.
Slovenian: Sproščanje citokinov je bilo inducirano po dermalni in peroralni uporabi imikvimoda tudi pri različnih drugih laboratorijskih živalih in v študijah na ljudeh.
English: Each sachet contains 9.375 mg of imiquimod in 250 mg cream (100 mg of cream contains 3.75 mg imiquimod).
Slovenian: Ena vrečica vsebuje 9,375 mg imikvimoda v 250 mg kreme (100 mg kreme vsebuje 3,75 mg imikvimoda).
English: Zyclara has no or negligible influence on the ability to drive and use machines.
Slovenian: Zdravilo Zyclara nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
English: Cream.
Slovenian: krema
English: While using Zyclara, you may experience local skin reactions because of the way it acts on your skin.
Slovenian: Med zdravljenjem z zdravilom Zyclara boste morda občutili lokalne kožne reakcije, ki izvirajo iz njenega lokalnega delovanja na kožo.
English: The treatment area is the full face or balding scalp.
Slovenian: Predela zdravljenja sta celoten obraz ali neporaščeno lasišče.
English: Rare (may affect up to 1 in 1,000 people) - Flaring up of autoimmune conditions (a disease that results from an abnormal immune response is an autoimmune disease) - Skin reactions remote from the application site
Slovenian: Redki (pojavijo se pri 1od 1.000 bolnikov) - poslabšanje avtoimunskih obolenj (bolezen, ki je posledica nenormalnega imunskega odziva,
English: - Each Zyclara 3.75% cream sachet contains 250 mg of a white to slightly yellow cream with a uniform appearance.
Slovenian: - Ena vrečica zdravila Zyclara 3,75 % krema vsebuje 250 mg bele do svetlo rumene kreme z enotnim videzom.
English: Each sachet contains 9.375 mg of imiquimod in 250 mg cream (3.75%).
Slovenian: Ena vrečica vsebuje 9,375 mg imikvimoda v 250 mg kreme (3,75 %).
English: In case a dose is missed, patients should wait until the forthcoming night to apply Zyclara and then continue with the regular schedule.
Slovenian: Če bolnik pozabi uporabiti odmerek, naj počaka do naslednjega večera in zdravilo Zyclara uporabi takrat, nato pa naj nadaljuje z običajnim urnikom zdravljenja.
English: Zyclara 3.75% cream contains the active substance imiquimod, which is an Immune Response Modifier (to stimulate the human immune system).
Slovenian: Zdravilo Zyclara 3,75 % krema vsebuje učinkovino imikvimod, ki je modifikator imunskega odziva
English: Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/fetal development, parturition or postnatal development (see section 5.3).
Slovenian: Študije na živalih ne kažejo neposrednih ali posrednih škodljivih učinkov na nosečnost, razvoj zarodka/plodu,
English: Non-clinical data revealed no special hazard for humans based on conventional studies of safety pharmacology, mutagenicity and teratogenicity.
Slovenian: Neklinični podatki na osnovi običajnih študij farmakološke varnosti, mutagenosti in teratogenosti ne kažejo posebnega tveganja za človeka.
English: In these studies, the treated AK field was located on the balding scalp or face with a contiguous area of about 40 cm² and presenting with a median number of 7 clinically typical AK lesions at baseline.
Slovenian: V teh študijah so se zdravljeni AK predeli nahajali na neporaščenem lasišču ali obrazu s sklenjeno površino približno 40 cm², mediana števila klinično značilnih AK lezij v izhodišču je bila 7.
English: If flu-like symptoms or feeling discomfort or intense local skin reactions occur, a rest period of several days may be taken.
Slovenian: Če se pojavijo gripi podobni simptomi, občutek neugodja ali hude kožne reakcije, lahko vzamete nekaj dni premora.
English: The incidence corresponds well with the spectrum of spontaneous tumours, as is known in mice in correspondence with their age.
Slovenian: Pojavnost se ujema z znano stopnjo pojavnosti spontanih tumorjev pri miših, v odvisnosti od starosti živali.
English: You should continue application for the full treatment course even if all actinic keratosis appear to be gone.
Slovenian: Z nanašanjem kreme morate nadaljevati skozi celoten ciklus zdravljenja, tudi če se zdi, da so vse aktinične keratoze izginile.
English: Cetyl alcohol and stearyl alcohol may cause local skin reactions (e.g. contact dermatitis).
Slovenian: Cetilalkohol in stearilalkohol lahko povzročita lokalne kožne reakcije (npr. kontaktni dermatitis).
English: Zyclara should be applied as a thin film to the entire treatment area and rubbed in until the cream vanishes.
Slovenian: Zdravilo Zyclara je treba v zelo tankem sloju nanesti na celotno zdravljeno področje in ga vtreti v kožo, dokler se ne vpije.
English: How to use Zyclara
Slovenian: Kako uporabljati zdravilo Zyclara
English: Content of the pack and other information
Slovenian: Shranjevanje zdravila Zyclara Vsebina pakiranja in dodatne informacije
English: Patients with cardiac, hepatic or renal impairment were not included in clinical trials.
Slovenian: Bolniki z okvaro srca, jeter ali ledvic v klinične študije niso bili vključeni.
English: Dry hands thoroughly and allow the area to dry.
Slovenian: Roke in zdravljeni predel nato skrbno osušite.
English: General instructions during treatment
Slovenian: Splošna navodila, ki jih je treba upoštevati med zdravljenjem
English: Imiquimod is not recommended for the treatment of AK lesions with marked hyperkeratosis or hypertrophy as seen in cutaneous horns.
Slovenian: Uporaba imikvimoda ni priporočena za zdravljenje AK lezij z izrazito hiperkeratozo ali hipertrofijo,
English: When applied topically, systemic overdose with imiquimod cream is unlikely due to minimal percutaneous absorption.
Slovenian: Sistemsko preveliko odmerjanje imikvimod kreme po lokalnem nanašanju ni verjetno zaradi minimalne perkutane absorpcije.
English: Apply a thin layer of Zyclara to the affected area.
Slovenian: Nanesite tanek sloj zdravila Zyclara na zdravljeni predel.
English: Treatment with imiquimod cream can be resumed after the skin reaction has moderated.
Slovenian: Zdravljenje z imikvimod kremo lahko nadaljujete, ko se kožne reakcije umirijo.
English: Stearyl alcohol and cetyl alcohol may cause local skin reactions (e.g. contact dermatitis).
Slovenian: Stearilalkohol in cetilalkohol lahko povzročita lokalne kožne reakcije (npr. kontaktni dermatitis).