FrancophonIA/ELRC3.0 huggingface dataset:
English: Therefore, the clinical consequences of drug interactions for letermovir will be dependent on which letermovir regimen is used and whether or not letermovir is combined with cyclosporine.
Danish: Derfor vil de kliniske konsekvenser af lægemiddelinteraktioner for letermovir være afhængig af, hvilket letermovir-regime der anvendes, og hvorvidt letermovir kombineres med ciclosporin eller ej. - Kombinationen af ciclosporin og letermovir kan føre til en mere udtalt virkning eller yderligere virkning af samtidigt administrerede lægemidler sammenlignet med letermovir som monoterapi (se tabel 1).
English: Any unused portion of the infusion solution should be discarded.
Danish: Eventuel resterende infusionsvæske skal kasseres.
English: Co-administration of PREVYMIS and etravirine is not recommended.
Danish: Samtidig administration af PREVYMIS og etravirin anbefales ikke.
English: Each vial contains 240 mg or 480 mg letermovir.
Danish: Hvert hætteglas indeholder 240 mg eller 480 mg letermovir.
English: PREVYMIS 240 mg film-coated tablets PREVYMIS 480 mg film-coated tablets
Danish: PREVYMIS 240 mg filmovertrukne tabletter PREVYMIS 480 mg filmovertrukne tabletter
English: Co-administration of PREVYMIS and efavirenz is not recommended.
Danish: Samtidig administration af PREVYMIS og efavirenz anbefales ikke.
English: • Do not shake PREVYMIS vial.
Danish: • Omryst ikke hætteglasset med Prevymis.
English: If monitoring is applied, this is recommended the first 2 weeks after initiating and ending letermovir (see section 4.4) as well as after changing route of letermovir administration.
Danish: Hvis der udføres monitorering, anbefales det de første 2 uger efter initiering og afslutning af behandling med letermovir (se pkt.
English: (600 mg single dose IV)/ letermovir (480 mg single dose PO)
Danish: (600 mg enkeltdosis IV)/letermovir (480 mg enkeltdosis oralt)
English: What you need to know before you are given PREVYMIS 3.
Danish: Det skal du vide, før du får Prevymis 3.
English: Outer carton for 480 mg concentrate for solution for infusion
Danish: Ydre karton til 480 mg koncentrat til infusionsvæske, opløsning
English: If PREVYMIS is co-administered with cyclosporine, the dosage of PREVYMIS should be decreased to 240 mg once daily (see sections 4.2 and 5.1).
Danish: Hvis PREVYMIS administreres sammen med ciclosporin, skal dosis af PREVYMIS nedsættes til 240 mg en gang dagligt (se pkt.
English: Each 12 mL vial contains 240 mg letermovir.
Danish: Hvert 12 ml hætteglas indeholder 240 mg letermovir.
English: Multiple dose rifampicin decreases plasma concentrations of letermovir.
Danish: Multiple doser rifampicin nedsætter plasmakoncentrationen af letermovir.
English: # (see section 4.4).
Danish: 4.4 og 4.5).
English: • Fentanyl citrate
Danish: • Fentanylcitrat
English: (600 mg once daily PO)/ letermovir (480 mg once daily PO)
Danish: (600 mg oralt en gang dagligt)/letermovir (480 mg oralt en gang dagligt)
English: 240 mg film-coated tablets
Danish: 240 mg filmovertrukne tabletter
English: ↑ cyclosporine AUC 1.66 (1.51, 1.82) Cmax 1.08 (0.97, 1.19) (CYP3A inhibition)
Danish: ↑ ciclosporin AUC 1,66 (1,51; 1,82) Cmax 1,08 (0,97; 1,19)
English: How to take PREVYMIS
Danish: Sådan skal du tage Prevymis
English: PREVYMIS concentrate for solution for infusion vials are for single use only.
Danish: Hætteglassene med Prevymis koncentrat til infusionsvæske, opløsning, er kun til engangsbrug.
English: Anti-arrhythmic medicinal products amiodarone
Danish: Antiarytmika amiodaron
English: 480 mg film-coated tablets
Danish: 480 mg filmovertrukne tabletter
English: Outer carton for 240 mg concentrate for solution for infusion
Danish: Ydre karton til 240 mg koncentrat til infusionsvæske, opløsning
English: Each 24 mL vial contains 480 mg of letermovir.
Danish: Hvert 24 ml hætteglas indeholder 480 mg letermovir.
English: Difference (95% CI) p-value
Danish: Stratumjusteret behandlingsforskel (letermovir-placebo) Forskel (95 % CI) p-værdi
English: PREVYMIS 240 mg film-coated tablets PREVYMIS 480 mg film-coated tablets letermovir
Danish: Prevymis 240 mg filmovertrukne tabletter Prevymis 480 mg filmovertrukne tabletter letermovir
English: List of compatible medicinal products when PREVYMIS and medicinal products* are prepared in 5% dextrose
Danish: Liste over kompatible lægemidler, når Prevymis og lægemidlerne* klargøres i 5 % glucose • Amphotericin B (lipidkompleks)
English: What PREVYMIS contains
Danish: Prevymis indeholder lactose
English: (600 mg single dose PO)/ letermovir (480 mg single dose PO)
Danish: (600 mg enkeltdosis oralt)/letermovir (480 mg enkeltdosis oralt)
English: Vial label for 480 mg concentrate for solution for infusion
Danish: Etiket til hætteglas til 480 mg koncentrat til infusionsvæske, opløsning
English: What you need to know before you are given PREVYMIS
Danish: Det skal du vide, før du får Prevymis
English: 480 mg IV, no cyclosporine
Danish: 480 mg intravenøst, uden ciclosporin
English: • Ganciclovir sodium
Danish: • Ganciclovirnatrium
English: PREVYMIS 240 mg concentrate for solution for infusion letermovir
Danish: PREVYMIS 240 mg koncentrat til infusionsvæske, opløsning letermovir
English: • Potassium chloride
Danish: Kaliumchlorid
English: Rifabutin may decrease plasma concentrations of letermovir.
Danish: Rifabutin kan nedsætte plasmakoncentrationen af letermovir.
English: (600 mg once daily PO (24 hours after rifampicin)) letermovir (480 mg once daily PO)
Danish: (600 mg oralt en gang dagligt (24 timer efter rifampicin))
English: Nafcillin may decrease plasma concentrations of letermovir.
Danish: Nafcillin kan nedsætte plasmakoncentrationen af letermovir.
English: Concomitant medicinal product
Danish: Samtidigt anvendt lægemiddel
English: Expected: ↔ valacyclovir
Danish: Forventet: ↔ valaciclovir
English: Bosentan may decrease plasma concentrations of letermovir.
Danish: Bosentan kan nedsætte plasmakoncentrationen af letermovir.
English: Vial label for 240 mg concentrate for solution for infusion
Danish: Etiket til hætteglas til 240 mg koncentrat til infusionsvæske, opløsning
English: • Potassium phosphate
Danish: Kaliumfosfat
English: The diluted solution should be inspected visually for particulate matter and discolouration prior to administration, whenever solution and container permit.
Danish: Den fortyndede infusionsvæske skal, når infusionsvæsken og beholderen gør det muligt, inspiceres visuelt for partikler og misfarvning før administration.
English: PREVYMIS 240 mg film-coated tablets
Danish: PREVYMIS 240 mg filmovertrukne tabletter
English: PREVYMIS 480 mg film-coated tablets
Danish: PREVYMIS 480 mg filmovertrukne tabletter
English: (OATP1B1/3 and/or BCRP inhibition)
Danish: (OATP1B1/3- og/eller BCRPhæmning)
English: Thioridazine may decrease plasma concentrations of letermovir.
Danish: Thioridazin kan nedsætte plasmakoncentrationen af letermovir.
English: (induction of CYP2C19)
Danish: (CYP2C19-induktion)
English: PREVYMIS 480 mg film-coated tablets letermovir
Danish: PREVYMIS 480 mg filmovertrukne tabletter letermovir
English: Storage of diluted solution
Danish: Opbevaring af den fortyndede infusionsvæske
English: PREVYMIS 240 mg film-coated tablets letermovir
Danish: PREVYMIS 240 mg filmovertrukne tabletter letermovir
English: Co-administration of PREVYMIS and St. John's wort is contraindicated.
Danish: Samtidig administration af PREVYMIS og perikon er kontraindiceret.
English: Frequent monitoring of sirolimus whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of sirolimus adjusted accordingly Frequent monitoring of sirolimus concentrations is recommended at initiation or discontinuation of cyclosporine coadministration with PREVYMIS.
Danish: Der bør foretages hyppig monitorering af sirolimuskoncentrationen i fuldblod under behandlingen, ved skift af administrationsvej for PREVYMIS og ved seponering af PREVYMIS, og sirolimus-dosis skal justeres i overensstemmelse hermed
English: PREVYMIS is not recommended in patients with moderate hepatic impairment combined with moderate or severe renal impairment (see section 5.2).
Danish: Kombination af nedsat leverfunktion og nedsat nyrefunktion PREVYMIS frarådes hos patienter med moderat nedsat leverfunktion i kombination med moderat nedsat eller svært nedsat nyrefunktion (se pkt.
English: Modafinil may decrease plasma concentrations of letermovir.
Danish: Modafinil kan nedsætte plasmakoncentrationen af letermovir.
English: PREVYMIS 480 mg concentrate for solution for infusion letermovir
Danish: PREVYMIS 480 mg koncentrat til infusionsvæske, opløsning letermovir
English: Phenytoin may decrease plasma concentrations of letermovir.
Danish: Phenytoin kan nedsætte plasmakoncentrationen af letermovir.
English: When PREVYMIS is co-administered with cyclosporine, dabigatran is contraindicated.
Danish: Dabigatran er kontraindiceret, når PREVYMIS administreres sammen med ciclosporin.
English: PREVYMIS contains lactose monohydrate.
Danish: Prevymis indeholder lactosemonohydrat.
English: Efavirenz may decrease plasma concentrations of letermovir.
Danish: Efavirenz kan nedsætte plasmakoncentrationen af letermovir.
English: • Norepinephrine bitartrate
Danish: Noradrenalinbitartrat
English: This should be taken into consideration by patients on a controlled sodium diet. PREVYMIS 480 mg concentrate for solution for infusion contains 46 mg (or 2.0 mmol) sodium per dose.
Danish: PREVYMIS 480 mg koncentrat til infusionsvæske, opløsning, indeholder 46 mg (eller 2,0 mmol) natrium pr. dosis.
English: Antivirals acyclovir (400 mg single dose)/ letermovir (480 mg daily)
Danish: Antivirale midler aciclovir (400 mg enkeltdosis)/ letermovir (480 mg dagligt)
English: 5% dextrose solutions.
Danish: 0,9 % natriumchloridopløsning og 5 % glucoseopløsning.
English: Expected: ↓ warfarin
Danish: ↓ warfarin
English: Nevirapine may decrease plasma concentrations of letermovir.
Danish: Nevirapin kan nedsætte plasmakoncentrationen af letermovir.
English: The recommended dosage of PREVYMIS is one 480 mg tablet once daily.
Danish: Den anbefalede dosis af PREVYMIS er en 480 mg tablet en gang dagligt.
English: The recommended dosage of PREVYMIS is 480 mg once daily.
Danish: Den anbefalede dosis af Prevymis er 480 mg en gang dagligt.
English: Contains sodium and cyclodextrin.. See package leaflet for further information.
Danish: Indeholder natrium og cyclodextrin.
English: Etravirine may decrease plasma concentrations of letermovir.
Danish: Etravirin kan nedsætte plasmakoncentrationen af letermovir.
English: • Pantoprazole sodium
Danish: Pantoprazolnatrium
English: If you are on a low sodium diet, talk to your doctor before you are given this medicine.
Danish: Fortæl det til lægen, før du får dette lægemiddel, hvis du er på en diæt med et lavt natriumindhold.
English: If you have any further questions on the use of this medicine, ask your doctor, pharmacist, or nurse.
Danish: Er du i tvivl, så spørg lægen eller apotekspersonalet.
English: Excretion
Danish: Klargøring
English: When PREVYMIS is co-administered with cyclosporine, atorvastatin is contraindicated.
Danish: Atorvastatin er kontraindiceret, når PREVYMIS administreres sammen med ciclosporin.
English: Refer to the respective prescribing information.
Danish: Se det tilhørende produktresumé.
English: PREVYMIS concentrate for solution for infusion requires dilution (see section 6.6) prior to administration.
Danish: PREVYMIS koncentrat til infusionsvæske, opløsning, skal fortyndes (se pkt.
English: • If cyclosporine is initiated after starting PREVYMIS, the next dose of PREVYMIS should be decreased to 240 mg once daily.
Danish: • Hvis ciclosporin initieres efter opstart med PREVYMIS, bør den efterfølgende dosis af
English: If you have a kidney disease, talk to your doctor before you receive this medicine.
Danish: Fortæl det til lægen, før du får dette lægemiddel, hvis du har en nyresygdom.
English: Letermovir may increase statin plasma concentrations.
Danish: Letermovir kan øge plasmakoncentrationerne af statiner.
English: • If you have any further questions, ask your doctor, pharmacist, or nurse.
Danish: • Spørg lægen, apotekspersonalet eller sundhedspersonalet, hvis der er mere, du vil vide.
English: • Cefazolin sodium
Danish: • Cefazolinnatrium
English: ↔ fluconazole AUC 1.03 (0.99, 1.08) Cmax 0.95 (0.92, 0.99) ↔ letermovir AUC 1.11 (1.01, 1.23) Cmax 1.06 (0.93, 1.21)
Danish: ↔ fluconazol AUC 1,03 (0,99; 1,08) Cmax 0,95 (0,92; 0,99)
English: Name and address of the manufacturer(s) responsible for batch release Schering-Plough Labo NV
Danish: Schering-Plough Labo NV Industriepark 30
English: Administration See section 4.2.
Danish: Virkning og anvendelse 2.
English: --¹ not less than 10E6.0 CCID50
Danish: --¹ Ikke mindre end 106.0 CCID50
English: 1 oral applicator
Danish: 1 oral applikator
English: 1 glass container + 1 oral applicator + 1 transfer adapter
Danish: 1 glasbeholder + 1 oral applikator + 1 overførselsaggregat transfer adapter
English: 1 squeezable tube multi-monodose (5 single dose) squeezable tube (polyethylene) presentation connected by a bar
Danish: --¹ Oral suspension Oral anvendelse Multi-enkeltdosis bestående af 5 sammenhængende enkeltdoser i bløde tuber (polyethylen)
English: It will be given once a day, for up to 7 days.
Danish: Fasturtec gives én gang daglig, i op til 7 dage.
English: Inspect visually prior to use.
Danish: Kontrolleres visuelt før brug.
English: Your doctor may also test your blood to make sure that you do not develop any blood disorders.
Danish: Lægen kan også teste dit blod for at sikre sig, at du ikke udvikler blodsygdomme.
English: 1 mg corresponds to 18.2 EAU*.
Danish: 1 mg svarer til 18,2 EAU*.
English: These may be the first signs that a severe allergic reaction is happening.
Danish: Dette kan være de første tegn på en alvorlig allergisk reaktion.
English: Only clear and colourless solutions without particles should be used.
Danish: Kun klare og farveløse opløsninger uden partikler bør anvendes.
English: Dilution before infusion:
Danish: Fortynding før infusion:
English: Do not use this medicine if you notice that the solution is unclear and/or contains particles.
Danish: Brug ikke dette lægemiddel, hvis opløsningen er uklar og/eller indeholder partikler.
English: These are rare (may affect up to 1 in 1,000 people).
Danish: Disse er sjældne (kan påvirke op til 1 ud af 1.000 personer).
English: It is not known whether the chance of developing an allergic reaction is increased if treatment with Fasturtec is repeated.
Danish: Det vides ikke, om risikoen for at udvikle en allergisk reaktion øges, hvis behandlingen med Fasturtec gentages.
English: Tell your doctor immediately if you notice any of the following as you may need to stop treatment:
Danish: Kontakt straks din læge, hvis du bemærker et eller flere af følgende symptomer, da det kan være nødvendigt at stoppe behandlingen:
English: No filter should be used for infusion.
Danish: Der bør ikke anvendes filter ved infusionen.
English: Your dose will be calculated according to your body weight.
Danish: Dosis beregnes ud fra din legemsvægt.
English: 9 SPECIAL STORAGE CONDITIONS Store in a refrigerator
Danish: SÆRLIGE OPBEVARINGSBETINGELSER Opbevares i køleskab
English: Clearance is increased (ca. 35%) in children and adolescents compared to adults, resulting in a lower systemic exposure.
Danish: Clearance er øget (ca. 35%) hos børn og unge sammenlignet med voksne, førende til lavere systemisk eksponering.
English: Your treatment with Fasturtec may need to be stopped, and you may need further treatment.
Danish: Det kan være nødvendigt at stoppe behandlingen med Fasturtec, og du kan have brug for anden behandling.
English: Fasturtec is supplied as a pack of:
Danish: Fasturtec leveres i en pakning med:
English: - Allergy/ allergic reactions (rashes and urticaria)
Danish: -Allergi/ allergiske reaktioner (udslæt og urticaria)
English: Tabulated list of adverse reactions MedDRA Organ system classes
Danish: Tabel over bivirkninger MedDRA Systemorgan klasser
English: Frequencies are defined using the following MedDRA convention as: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Danish: konventionen, er: meget almindelig (≥1/10); almindelig (≥ 1/100 til <1/10); ikke almindelig (≥1/1.000 til <1/100); sjælden (≥1/10.000 til 1/1.000); meget sjælden (<1/10.000); ikke kendt (kan ikke estimeres ud fra forhåndenværende data).
English: The powder is an entire or broken white to off white pellet.
Danish: Pulveret er en helt eller brækket hvid til offwhite pellet.
English: Results showed a significantly more rapid onset of action of Fasturtec in comparison with allopurinol.
Danish: Resultaterne viste en signifikant hurtigere virkning af Fasturtec sammenlignet med allopurinol.
English: Frequency not known (frequency cannot be estimated from the available data) - involuntary muscle movements (muscle contraction involuntary).
Danish: Ikke kendt (hyppigheden kan ikke vurderes ud fra tilgængelige data): − Ufrivillige muskelsammentrækninger.
English: EXP Use immediately after reconstitution or dilution
Danish: EXP Anvendes umiddelbart efter rekonstitution eller fortynding
English: Safety results on 246 patients were consistent with the adverse events profile in the overall population.
Danish: Sikkerhedsresultater fra 246 patienter stemte overens med bivirkningsprofilen i hele populationen.
English: Date of latest renewal: 23 February 2006
Danish: Dato for første markedsføringstilladelse: 23. februar 2001 Dato for seneste fornyelse: 23. februar 2006
English: The following information is intended for healthcare professionals only: See section 3 “How to use Fasturtec” and practical information on preparation and handling given below.
Danish: Nedenstående oplysninger er til læger og sundhedspersonale: Se punkt 3 ”Sådan skal du bruge Fasturtec” samt praktisk information om fremstilling og håndtering nedenfor.
English: - Severe hypersensitivity reactions
Danish: -Alvorlige overfølsomhedsreaktioner
English: Because teratogenic effects of rasburicase cannot be ruled out, Fasturtec should only be used during pregnancy if strictly necessary.
Danish: Idet teratogene virkninger af rasburikase ikke kan udelukkes, bør Fasturtec kun anvendes under graviditet, såfremt det er strengt nødvendigt.
English: There are no data from the use of rasburicase in pregnant women.
Danish: Der er ingen data fra anvendelse af rasburikase til gravide kvinder.
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity and genotoxicity.
Danish: Ikke-kliniske data har ikke afsløret specifikke risici for mennesker i konventionelle studier af farmakologisk sikkerhed, toksikologi og genotoksicitet.
English: Efficacy results on 229 evaluable patients showed an overall response rate (normalization of plasma uric acid levels) of 96.1%.
Danish: Effektiviteten målt på 229 patienter viste en generel responsrate (normalisering af plasma-urinsyre-niveau) på 96,1%.
English: Rasburicase is a protein, and therefore: 1) not expected to bind to proteins, 2) expected that metabolic degradation will follow the pathways of other proteins, i.e. peptide hydrolysis, 3) unlikely to be candidate for drug-drug interactions.
Danish: Rasburikase er et protein, hvorfor det: 1) ikke forventes at bindes til andre proteiner, 2) forventes at blive metaboliseret som andre proteiner, hvilket vil sige ved peptidhydrolyse, 3) sandsynligvis ikke vil have interaktioner med andre lægemidler.
English: - Bronchospasm - Rhinitis
Danish: -Bronkospasme -Rhinitis
English: The solvent is a colourless and clear liquid.
Danish: Solventen er en farveløs og klar væske.
English: Time to first confirmation of normal levels of uric acid in hyperuricaemic patients is four hours for Fasturtec and 24 hours for allopurinol.
Danish: Tidsrummet frem til første bekræftede normalisering af urinsyreværdier hos patienter med hyperurikæmi er 4 timer for Fasturtec og 24 timer for allopurinol.
English: Fasturtec will be administered at the same time as other medicines that may also cause side effects.
Danish: Fasturtec gives sammen med andre lægemidler, som også kan give bivirkninger.
English: The most commonly reported adverse reactions were nausea, vomiting, headache, fever, and diarrhea.
Danish: De hyppigst rapporterede bivirkninger var kvalme, opkastning, hovedpine, feber og diarré.
English: What you need to know before you are given Fasturtec 3.
Danish: Det skal du vide, før du begynder at få Fasturtec 3.
English: It is unknown whether rasburicase is excreted in human milk.
Danish: Det er ukendt, om rasburikase udskilles i human mælk.
English: The safety results of patients treated with Fasturtec in Study EFC4978 were consistent with the adverse events profile observed in previous clinical studies with predominantly paediatric patients.
Danish: Sikkerhedsdata for patienter behandlet med Fasturtec i studium EFC4978 var i overensstemmelse med den bivirkningsprofil, der blev set i tidligere kliniske studier med fortrinsvis pædiatriske patienter.
English: Plasma samples should immediately be prepared by centrifugation in a pre-cooled centrifuge (4°C).
Danish: Plasmaprøverne tilberedes straks ved centrifugering i en nedkølet centrifuge (4°C).
English: Fasturtec is to be given to you before or during the start of your course of chemotherapy.
Danish: Fasturtec skal gives inden eller i begyndelsen af dit kemoterapiforløb.
English: *One enzyme activity unit (EAU) corresponds to the enzyme activity that converts 1 µmol of uric acid into allantoin per minute under the operating conditions described: +30 °C ± 1 °C TEA pH 8.9 buffer.
Danish: *En «enzyme activity unit» (EAU) svarer til den enzymaktivitet, der kan omdanne 1 µmol urinsyre til allantoin per minut under følgende forhold: +30°C±1°C TEA pH 8,9 buffer.
English: After infusion of rasburicase at a dose of 0.20 mg/kg/day, steady state is achieved at day 2 - 3.
Danish: Efter infusion af rasburikase i doser på 0,20 mg/kg/dag opnås steady state på dag 2-3.
English: - Muscle contraction involuntary**
Danish: - Ufrivillige muskelSammentrækninger**
English: Sanofi Chimie Route d'Avignon 30390 Aramon France
Danish: Sanofi Chimie Route d'Avignon 30390 Aramon Frankrig
English: Finally, plasma must be maintained in an ice/water bath and analysed for uric acid within 4 hours.
Danish: Endelig skal plasma opbevares i bad med is/vand og analyseres for urinsyre inden for 4 timer.
English: Rasburicase is a tetrameric protein with identical subunits of a molecular mass of about 34 kDa.
Danish: Rasburikase er et tetramert protein med identiske underenheder af en molekylmasse på ca. 34 kDa.
English: Pharmacotherapeutic group: Detoxifying agents for antineoplastic treatment, ATC code: V03AF07.
Danish: Farmakoterapeutisk klassifikation: Afgiftningsmidler ved cytostatica-behandling, ATC-kode: V03AF07
English: Special populations Renally or hepatically impaired patients: No dose adjustment is necessary.
Danish: Særlige populationer Patienter med nedsat nyre- eller leverfunktion: Dosisjustering er ikke nødvendig.
English: What Fasturtec contains
Danish: Fasturtec indeholder
English: The mean terminal half-life was similar between paediatric and adult patients and ranged from 15.7 to 22.5 hours.
Danish: Den gennemsnitlige terminale halveringstid var sammenlignelig for pædiatriske og voksne patienter og i størrelsesordnen 15,7-22,5 timer.
English: Rasburicase solution should be infused over 30 minutes.
Danish: Rasburikase skal indgives over 30 minutter.
English: The concentration of rasburicase in the final solution for infusion depends on the patient's body weight.
Danish: Koncentrationen af rasburikase i den færdige infusionsopløsning afhænger af patientens legemsvægt.
English: During treatment with Fasturtec, the advantage of breastfeeding should be weighted against the potential risk for the infant.
Danish: Ved behandling med Fasturtec skal fordelene ved amning afvejes i forhold til den potentielle risiko for barnet.