FrancophonIA/ELRC3.0 huggingface dataset:
English: Zerit 15 mg hard capsules Zerit 20 mg hard capsules Zerit 30 mg hard capsules Zerit 40 mg hard capsules
Danish: Zerit 15 mg hårde kapsler Zerit 20 mg hårde kapsler Zerit 30 mg hårde kapsler Zerit 40 mg hårde kapsler
English: Cmax and AUC increased proportionally with dose in the dose ranges, intravenous 0.0625-0.75 mg/kg, and oral 0.033-4.0 mg/kg.
Danish: Cmax og AUC øgedes proportionalt med dosis i dosisintervallet, 0,0625-0,75 mg/kg intravenøst og 0,033-4,0 mg/kg peroralt.
English: The solution should be dispensed with the measuring cup provided, or for doses less than 10 ml, dispense with a syringe.
Danish: Opløsningen skal udleveres med det vedlagte målebæger, eller udlever med en sprøjte, hvis dosis er mindre end 10 ml.
English: Do not use this medicine after the expiry date which is stated on the carton, the bottle label and/or the blister after EXP.
Danish: Brug ikke lægemidlet efter den udløbsdato, der står på æsken eller etiketten på glasset og/eller på blisterkortet efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: After multiple oral administration of 0.5-0.67 mg/kg doses, a Cmax value of 810±175 ng/ml was obtained.
Danish: Efter multiple orale administrationer med doser på 0,5-0,67 mg/kg blev en Cmax værdi på 810±175 ng/ml opnået.
English: Zerit has been studied in combination with other antiretroviral agents, e.g. didanosine, lamivudine, ritonavir, indinavir, saquinavir, efavirenz, and nelfinavir.
Danish: Zerit er undersøgt i kombination med andre antiretrovirale stoffer, f.eks. didanosin, lamivudin, ritonavir, indinavir, saquinavir, efavirenz og nelfinavir.
English: Peripheral neuropathy: if symptoms of peripheral neuropathy develop (usually characterised by persistent numbness, tingling, or pain in the feet and/or hands) (see section 4.4), patients should be switched to an alternative treatment regimen, if appropriate.
Danish: Perifer neuropati: Hvis der opstår symptomer på perifer neuropati (sædvanligvis karakteriseret ved vedvarende følelsesløshed, prikken eller smerte i fødder og/eller hænder) (se pkt 4.4), skal patienterne skiftes til andet behandlingsregime, såfremt dette er passende.
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Danish: Hos nogle patienter med fremskreden hiv-infektion (AIDS) som tidligere har haft opportunistisk infektion, kan tegn og symptomer på betændelse fra tidligere infektioner forekomme kort efter, at antihiv behandlingen er startet.
English: In vitro studies indicate that the activation of stavudine is inhibited by doxorubicin and ribavirin but not by other medicinal products used in HIV infection which are similarly phosphorylated, (e.g. didanosine, zalcitabine, ganciclovir and foscarnet) therefore, coadministration of stavudine with either doxorubicin or ribavirin should be undertaken with caution.
Danish: In vitro studier indikerer, at aktivering af stavudin hæmmes af doxorubicin og ribavirin men ikke af andre lægemidler til behandling af HIV-infektion, som fosforyleres på lignende måde (f.eks. didanosin, zalcitabin, ganciclovir og foscarnet); der bør derfor udvises forsigtighed ved samtidig administration af stavudin og doxorubicin eller ribavirin.
English: Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption, should not take this medicine.
Danish: Patienter med arvelig galactoseintolerans, en særlig form af arvelig lactasemangel (Lapp Lactase deficiency) eller glucose/galactosemalabsorption bør ikke anvende dette lægemiddel.
English: Children from birth to 13 days old should receive 0.5 mg/kg twice daily.
Danish: Nyfødte, fra fødslen til 13 dage, skal have 0,5 mg/kg to gange dagligt.
English: Dual energy x-ray absorptiometry (DEXA) scans demonstrated overall limb fat loss in stavudine treated patients compared to limb fat gain or no change in patients treated with other NRTIs (abacavir, tenofovir or zidovudine).
Danish: DEXA-(dual energy x-ray absorptiometry)-scanning har påvist generaliseret perifert fedttab hos patienter behandlet med stavudin sammenlignet med øget perifer fedtakkumulation eller ingen ændring hos patienter behandlet med andre NRTIer (abacavir, tenofovir eller zidovudin).
English: Mitochondrial dysfunction: review of the postmarketing safety database shows that adverse reactions indicative of mitochondrial dysfunction have been reported in the neonate and infant population exposed to one or more nucleoside analogues (see also section 4.4).
Danish: Mitokondriel dysfunktion: Gennemgang af postmarketing-sikkerhedsdatabasen viser, at bivirkninger, der antyder mitokondriel dysfunktion, er blevet rapporteret i populationen af nyfødte og spædbørn, der er blevet udsatte for en eller flere nukleosidanaloger (se også pkt.
English: UNIQUE IDENTIFIER - 2D BARCODE Outer carton: 2D barcode carrying the unique identifier included.
Danish: 17 ENTYDIG IDENTIFIKATOR - 2D-STREGKODE Ydre karton: Der er anført en 2D-stregkode, som indeholder en entydig identifikator.
English: Neutropenia (< 750 cells/mm3) was reported in 5%, thrombocytopenia (platelets < 50,000/mm3) in 2%, and low haemoglobin (< 8 g/dl) in < 1% of patients receiving Zerit.
Danish: Neutropeni (< 750 celler/mm3) blev rapporteret hos 5%, trombocytopeni (blodplader < 50.000/mm3) hos 2% og lav hæmoglobin (< 8 g/dl) hos < 1% af patienter, der blev behandlet med Zerit.
English: Apparent oral clearance was approximately 14 ml/min/kg for infants ages 5 weeks to 15 years, 12 ml/min/kg for infants ages 14 to 28 days, and 5 ml/min/kg for infants on the day of birth.
Danish: Den åbenbare orale clearance var ca. 14 ml/min./kg for patienter i alderen 5 uger til 15 år, 12 ml/min./kg for spædbørn i alderen 14-28 dage og 5 ml/min./kg for spædbørn på fødselstidspunktet.
English: Cases of lactic acidosis, sometimes fatal, usually associated with severe hepatomegaly and hepatic steatosis, have been reported in < 1% of patients taking stavudine in combination with other antiretrovirals (see section 4.4).
Danish: Der er rapporteret om tilfælde af laktatacidose, nogle gange letal, sædvanligvis forbundet med svær hepatomegali og hepatisk steatose hos < 1% af patienterne, behandlet med stavudin i kombination med andre antiretrovirale lægemidler (se pkt.
English: Also listed are adverse reactions observed post-marketing in association with stavudine-containing antiretroviral treatment.
Danish: Der er også anført bivirkninger, som er observeret post-marketing i forbindelse med antiretroviral behandling med stavudin.
English: Zerit contains lactose
Danish: Zerit indeholder lactose
English: Each bottle contains 31.5 mg of propylhydroxybenzoate (E216) Each bottle contains 315 mg of methylhydroxybenzoate (E218) Each bottle contains 10.15 g of sucrose
Danish: Hjælpestoffer, som behandleren skal være opmærksom på En flaske indeholder 31,5 mg propylhydroxybenzoat (E216) En flaske indeholder 315 mg methylhydroxybenzoat (E218) En flaske indeholder 10,15 g saccharose
English: There was, however, an increased infant mortality in the stavudine + didanosine (10%) treatment group compared to the stavudine (2%), didanosine (3%) or zidovudine (6%) groups, with a higher incidence of stillbirths in the stavudine + didanosine group.
Danish: Der var imidlertid en øget spædbørnsdødelighed i stavudin + didanosin (10%) behandlingsgruppen sammenlignet med stavudin (2%), didanosin (3%) eller zidovusin (6%) grupperne, med en højere incidens af dødfødte i stavudin + didanosin-gruppen.
English: In addition, rare cases of liver failure/renal failure or fatal hepatitis have been reported.
Danish: Endvidere er der rapporteret sjældne tilfælde af leversvigt/nyresvigt eller livsfarlig leverbetændelse.
English: The mean haemodialysis clearance of stavudine is 120 ml/min.
Danish: Stavudins gennemsnitlige clearance ved hæmodialyse er 120 ml/min.
English: PHARMACEUTICAL FORM AND CONTENTS Powder for oral solution, 200 mg
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) Pulver til oral opløsning, 200 mg
English: The powder contains 200 mg stavudine.
Danish: Pulveret indeholder 200 mg stavudin.
English: In study AI455-094 (see also section 4.6), the safety follow-up period was restricted to only six months, which may be insufficient to capture long-term data on neurological adverse events and mitochondrial toxicity.
Danish: 4.6) var opfølgningsperioden for sikkerhed begrænset til kun måneder, hvilket kan være utilstrækkeligt til at fange langtidsdata for neurologiske bivirkninger og mitokondriel toksicitet.
English: The main adverse reactions reported are haematological disorders (anaemia, neutropenia) and metabolic disorders (hyperlactatemia, hyperlipasemia).
Danish: De rapporterede overordnede bivirkninger er hæmatologiske forstyrrelser (anæmi, neutropeni) og metaboliske forstyrrelser (hyperlactatæmi, hyperlipasæmi).
English: Patients should be instructed that if they experience these symptoms they should avoid potentially hazardous tasks such as driving or operating machinery.
Danish: Patienter bør informes om at de skal undgå potentielle farlige gøremål såsom kørsel eller maskinbetjening, hvis de oplever disse symptomer.
English: PHARMACEUTICAL FORM AND CONTENTS 56 hard capsules
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) 56 hårde kapsler
English: Do not take Zerit if you are taking didanosine, used to treat HIV infection.
Danish: Du må ikke tage Zerit, hvis du tager didanosin til behandling af hiv-infektion.
English: Laboratory abnormalities: laboratory abnormalities reported in these two trials and an ongoing follow-up study included elevations of ALT (> 5 x ULN) in 3%, of AST (> 5 x ULN) in 3%, of lipase (≥ 2.1 ULN) in 3% of the patients in the Zerit group.
Danish: Abnorme laboratorieværdier: Abnorme laboratorieværdier rapporteret i disse to studier og et igangværende opfølgningsstudie omfattede stigninger af ALAT (> 5 x øvre normalgrænse) hos 3%, af ASAT (> 5 x øvre normalgrænse) hos 3%, af lipase (≥ 2,1 øvre normalgrænse) hos 3% af patienterne i Zerit-gruppen.
English: Co-administration with didanosine due to the potential for serious and/or life-threatening events notably lactic acidosis, liver function abnormalities, pancreatitis and peripheral neuropathy (see sections 4.4 and 4.5).
Danish: Samtidig administration af didanosin på grund af risiko for alvorlige og/eller livstruende bivirkninger, især laktatacidose, leverfunktionsabnormiteter, pankreatitis og perifer neuropati (se pkt.
English: Late-onset neurological disorders have been reported rarely (hypertonia, convulsion, abnormal behaviour).
Danish: I sjældne tilfælde er der rapporteret sent opståede neurologiske forstyrrelser (hypertoni, kramper, abnorm adfærd).
English: Immune reactivation syndrome: in HIV-infected patients with severe immune deficiency at the time of initiation of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Danish: Immunreaktiveringssyndrom: Hos HIV-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske infektioner.
English: Immune reactivation syndrome: in HIV-infected patients with severe immune deficiency at the time of institution of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic pathogens may arise and cause serious clinical conditions, or aggravation of symptoms.
Danish: Immunreaktiveringssyndrom: Hos HIV-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske patogener, som kan forårsage alvorlige kliniske tilstande eller forværring af symptomer.
English: For storage conditions of the reconstituted medicinal product, see section 6.3.
Danish: For opbevaringsforhold af den rekonstituerede opløsning, se pkt.
English: LIST OF EXCIPIENTS Lactose
Danish: LISTE OVER HJÆLPESTOFFER Lactose
English: Early symptoms (symptomatic hyperlactatemia) include benign digestive symptoms (nausea, vomiting and abdominal pain), non-specific malaise, loss of appetite, weight loss, respiratory symptoms (rapid and/or deep breathing) or neurological symptoms (including motor weakness).
Danish: Tidlige symptomer (symptomatisk hyperlaktatæmi) omfatter lette fordøjelsessymptomer (kvalme, opkastning og abdominalsmerter), uspecificeret utilpashed, appetitløshed, vægttab, respiratoriske symptomer (hurtigt og/eller besværet åndedræt) eller neurologiske symptomer (inklusiv motorisk svækkelse).
English: in 76 treatment-naive patients, with a median CD4 cell count of 261 cells/mm3
Danish: til 76 ikke tidligere behandlede patienter med et gennemsnitligt CD4-tal på 261 celler/mm3 (63
English: HIV RNA Mean Change from Baseline, log10 copies/ml All patients
Danish: HIV-RNA Gennemsnitsændring fra baseline, log10 kopier/ml Alle patienter
English: Weight and metabolic parameters: an increase in weight and in levels of blood lipids and glucose may occurr during antiretroviral therapy.
Danish: Vægt og metaboliske parametre: Vægtstigning og forhøjede lipider og glucose i blodet kan forekomme under antiretroviral behandling.
English: HDPE bottles with child resistant screw cap (60 hard capsules per bottle).
Danish: HDPE-beholder med børnesikret skruelåg (60 hårde kapsler/beholder)
English: At least 14 days old and < 30 kg ≥ 30 kg
Danish: Fra fødsel* til 13 dage gammel Mindst 14 dage gammel og < 30 kg ≥ 30 kg
English: When treating HIV infection, it is not always possible to differentiate between unwanted effects caused by Zerit, or those caused by any other medicines you may be taking at the same time, or by the complications of the infection.
Danish: Ved behandling af hiv-infektion, er det ikke altid muligt at skelne mellem bivirkninger, der er forårsaget af Zerit, bivirkninger, der skyldes anden medicin, som du eventuelt tager samtidig, eller bivirkninger, som er komplikationer til infektioner.
English: When reconstituted with 202 ml of water, produces 210 ml of a colorless to slightly pink, hazy solution.
Danish: Pulveret tilsættes 202 ml vand og resulterer i 210 ml farveløs til let lyserød og uklar opløsning.
English: Rare (may affect up to 1 in 1,000 people) anemia hyperglycaemia (high sugar levels in the blood)
Danish: Sjælden (kan forekomme hos op til 1 ud af 1.000 personer) anæmi hyperglykæmi (forhøjet blodsukker)
English: For adults whose body weight is 30 kg or more, the usual starting dose is 30 or 40 mg given twice daily (with approximately 12 hours between each dose).
Danish: For voksne, som vejer 30 kg eller derover, er den sædvanlige startdosis 30 eller 40 mg 2 gange dagligt (med ca. 12 timers interval mellem hver dosis).
English: If needed, consult your pharmacist for help with this procedure.
Danish: Om nødvendigt kan du rådføre dig med din læge eller apotekspersonalet angående blandingsproceduren.
English: In eight patients receiving 40 mg twice daily in the fasted state, steady-state AUC0-12h was 1284±227 ng⋅h/ml (18%) (mean ± SD [% CV]), Cmax was 536±146 ng/ml (27%), and Cmin was 9±8 ng/ml (89%).
Danish: Hos otte patienter, der fik 40 mg to gange dagligt fastende, var steady-state AUC0-12t 1.284±227 ng t/ml (18%) (mean ± SD) [%CV], Cmax var 536±146 ng/ml (27%) og Cmin var 9±8 ng/ml (89%).
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each bottle contains stavudine 200 mg The reconstituted solution contains 1 mg of stavudine per ml.
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER En flaske indeholder 200 mg stavudin Den tilberedte opløsning indeholder 1 mg stavudin per ml.
English: hepatic steatosis (fat in the liver)
Danish: leversteatose (fedtlever)
English: These studies include ACTG 240, where 105 paediatric patients ages 3 months to 6 years received Zerit 2 mg/kg/day for a median of 6.4 months; a controlled clinical trial where 185 newborns received Zerit 2 mg/kg/day either alone or in combination with didanosine from birth through 6 weeks of age; and a clinical trial where 8 newborns received Zerit 2 mg/kg/day in combination with didanosine and nelfinavir from birth through 4 weeks of age.
Danish: Disse studier omfatter ACTG 240, hvor 105 pædiatriske patienter i alderen 3 måneder til 6 år fik Zerit 2 mg/kg/dag for en median periode på 6,4 måneder; et kontrolleret klinisk forsøg, hvor 185 nyfødte fik Zerit 2 mg/kg/dag enten som enkeltstof eller i kombination med didanosin i de første 6 uger efter fødslen samt et klinisk forsøg, hvor 8 nyfødte fik Zerit 2 mg/kg/dag i kombination med didanosin og nelfinavir i de første 4 uger efter fødslen.
English: common: rash, pruritus uncommon: urticaria
Danish: Almindelig: udslæt, pruritus Ikke almindelig: urticaria
English: Metabolic parameters: weight and levels of blood lipids and glucose may increase during antiretroviral therapy (see section 4.4).
Danish: Metaboliske parametre: Kropsvægt og niveauerne af lipid og glucose i blodet kan stige under antiretroviral behandling (se pkt.
English: During treatment, other infections linked to a weakened immunity (opportunistic infections) may arise.
Danish: Under behandlingen kan der opstå andre infektioner (opportunistiske infektioner) på grund af det nedsatte immunforsvar.
English: When such development is found, treatment with Zerit should not be continued (see section 4.4).
Danish: Hvis der ses udvikling af lipoatrofi, bør behandlingen med Zerit ikke fortsættes (se pkt.
English: PHARMACEUTICAL FORM AND CONTENTS 60 hard capsules
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) 60 hårde kapsler
English: OUTER CARTON TEXT AND BOTTLE LABEL TEXT
Danish: TEKST TIL YDRE KARTON OG ETIKET TIL FLASKE
English: Very rare (may affect up to 1 in 10,000 people) thrombocytopenia, neutropenia (blood disorders) diabetes mellitus motor weakness (most often reported in the setting of symptomatic hyperlacetatemia or lactic acidosis syndrome) liver failure
Danish: Meget sjælden (kan forekomme hos op til 1 ud af 10.000 personer) trombocytopeni, neutropeni (blodsygdomme) sukkersyge (diabetes mellitus) motorisk svækkelse (oftest set ved tilfælde af symptomatisk hyperlaktatæmi eller laktatacidosesyndrom) leversvigt
English: Given these potential risks, a benefit-risk assessment for each patients should be made and an alternative antiretroviral should be carefully considered (see Lactic acidosis, Lipoatrophy, and Peripheral neuropathy below and section 4.8).
Danish: I betragtning af disse potentielle risici bør der foretages en afvejning af fordele og risici for hver enkelt patient, og et alternativt antiretroviralt præparat bør nøje overvejes (se Laktatacidose, Lipoatrofi og Perifer neuropati nedenfor i pkt.
English: Stavudine's influence on the phosphorylation kinetics of nucleoside analogues other than zidovudine has not been investigated.
Danish: Stavudins påvirkning af nukleosidanalogers fosforyleringskinetik, bortset fra zidovudin, er ikke undersøgt.
English: To help protect the capsules from excessive moisture, the bottle includes a desiccant canister.
Danish: For at beskytte kapslerne mod fugt er der indlagt en tørre-cylinder i glasset.
English: common: lipoatrophy**, asymptomatic hyperlactatemia uncommon: lactic acidosis (in some cases involving motor weakness), anorexia rare: hyperglycaemia* very rare: diabetes mellitis*
Danish: Almindelig: lipoatrofi**, asymptomatisk hyperlaktatæmi Ikke almindelig: laktatacidose (i nogle tilfælde med motorisk svækkelse), anoreksi
English: Blanchardstown Corporate Park 2 Dublin 15, D15 T867
Danish: Blanchardstown Corporate Park 2 Dublin 15
English: The other ingredients of the powder are: cherry flavour, methylhydroxybenzoate (E218), propylhydroxybenzoate (E216), silicon dioxide, simethicone, sodium carmellose, sorbic acid, stearate emulsifiers and sucrose.
Danish: - Øvrige indholdsstoffer i pulveret: kirsebærsmag, methylhydroxybenzoat (E218), propylhydroxybenzoat (E216), silica, simethicon, natriumcarmellose, sorbinsyre, stearatemulgeringsmidler og saccharose.
English: The total clearance of stavudine appears to be higher in HIV-infected patients, while the renal clearance is similar between healthy subjects and HIV-infected patients.
Danish: Den totale clearance af stavudin er tilsyneladende højere hos HIVinficerede patienter, mens den renale clearance hos raske individer og HIV-inficerede patienter er ens. Mekanismen og den kliniske signifikans af denne forskel kendes ikke.
English: common: peripheral neurologic symptoms including peripheral neuropathy, paresthesia, and peripheral neuritis; dizziness; abnormal dreams; headache, insomnia; abnormal thinking; somnolence very rare: motor weakness* (most often reported in the setting of symptomatic hyperlactatemia or lactic acidosis syndrome)
Danish: Almindelig: perifere neurologiske symptomer inklusive perifer neuropati, paræstesier og perifer neuritis, svimmelhed, abnorme drømme, hovedpine, søvnløshed, abnorme tanker, døsighed Meget sjælden: motorisk svækkelse* (hyppigst rapporteret i forbindelse med symptomatisk hyperlaktatæmi eller laktatacidosesyndrom)
English: METHOD AND ROUTE(S) OF ADMINISTRATION Oral use
Danish: ANVENDELSESMÅDE OG ADMINISTRATIONSVEJ Oral anvendelse
English: 30 mg twice daily (every 12 hours) 40 mg twice daily (every 12 hours)
Danish: 30 mg to gange dagligt (hver 12. time) 40 mg to gange dagligt (hver 12. time)
English: 20 mg twice daily 20 mg every 24 hours
Danish: 20 mg 2 gange dagligt 20 mg hver 24. time
English: Each bottle contains 200 mg of stavudine.
Danish: En flaske indeholder 200 mg af stavudin.
English: 15 mg twice daily 15 mg every 24 hours
Danish: 15 mg 2 gange dagligt 15 mg hver 24. time
English: Most of these cases occurred in the setting of symptomatic hyperlactatemia or lactic acidosis syndrome (see section 4.4).
Danish: De fleste episoder optrådte i forbindelse med symptomatisk hyperlaktatæmi eller laktatacidosesyndrom (se pkt.
English: If you are taking didanosine, used to treat HIV infection.
Danish: Hvis du tager didanosin til behandling af hiv-infektion.
English: 1 mg/kg twice daily (every 12 hours) adult dosing
Danish: 1 mg/kg to gange dagligt (hver 12. time) Voksendosis
English: Osteonecrosis: cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to combination antiretroviral therapy (CART).
Danish: Osteonekrose: Særligt hos patienter med generelt anerkendte risikofaktorer, fremskreden HIV-sygdom eller langvarig kombinationsbehandling med antiretrovirale lægemidler (CART) er der rapporteret om tilfælde af osteonekrose.
English: To obtain optimal absorption, the capsules should be swallowed with a glass of water, preferentially at least one hour before a meal and on an empty stomach.
Danish: For at opnå den bedste optagelse skal kapslerne sluges sammen med et glas vand og helst mindst 1 time før et måltid og på tom mave.
English: Stavudine was genotoxic in in vitro tests in human lymphocytes possessing triphosphorylating activity (in which no no-effect level was established), in mouse fibroblasts, and in an in vivo test for chromosomal aberrations.
Danish: Stavudin var genotoksisk i in vitro test af humane lymfocytter med trifosforylerings aktivitet (i hvilke, der ikke etableredes et ikke-effekt niveau).
English: The capsule shells are marked using edible black printing ink containing shellac, propylene glycol, purified water, potassium hydroxide and iron oxide (E172).
Danish: - Kapslen er mærket med spiseligt sort farvestof indeholdende shellac, propylenglycol, renset vand, kaliumhydroxid og jernoxid (E172).
English: For children whose body weight is 30 kg or more, the usual starting dose is 30 or 40 mg given twice daily (with approximately 12 hours between each dose).
Danish: Til børn, som vejer 30 kg eller derover, er den sædvanlige startdosis 30 eller 40 mg 2 gange dagligt (med ca. 12 timers interval mellem de to doser).
English: 3) and a median plasma HIV-1 RNA of 4.63 log10 copies/ml (range 3.0 to 5.9 log10 copies/ml) at baseline.
Danish: 3) og et gennemsnitligt plasma HIV-1 RNA på 4,63 log10 kopier/ml (3,0 til 5,9 log10 kopier/ml) ved baseline.