FrancophonIA/ELRC3.0 huggingface dataset:
English: The doctor may sometimes prescribe a different dose particularly if you are receiving, or have received, other treatments for your cancer or if you have kidney problems.
Croatian: Liječnik ponekad može propisati drukčiju dozu, pogotovo ako primate ili ste primali druge terapije za rak od kojeg bolujete ili imate probleme s bubrezima.
English: Facial flushing was reported in 2% of patients and skin rashes in 3%.
Croatian: Navale crvenila lica prijavljene su u 2% bolesnika, a osip na koži u 3%.
English: Both male and female patients who are considering having a child after having treatment with ETOPOPHOS and associated names should discuss this with their doctor or nurse.
Croatian: I muški i ženski bolesnici koji razmišljaju o tome da imaju dijete nakon liječenja ETOPOPHOSOM i pridruženim imenima, o tome se trebaju savjetovati sa svojim liječnikom ili medicinskom sestrom.
English: • 0.9 % sodium chloride solution.
Croatian: • 0,9%-tne otopine natrijevog klorida.
English: It will be given as a slow infusion into a vein.
Croatian: Primat ćete ga polaganom infuzijom u venu.
English: The mean volumes of distribution at steady state range from 18 to 29 liters .
Croatian: Srednji volumeni distribucije u stanju dinamičke ravnoteže kreću se u rasponu od 18 do 29 litara.
English: If spikes are used they should be equipped with particle filters or other measures should be taken (e.g. inline-filters) to ensure that only particle free solutions are administered.
Croatian: Ako se koriste šiljasti nastavci, treba ih opremiti filtrima za čestice ili treba poduzeti druge mjere (npr.upotrijebiti ugrađene filtre) kako bi se osigurala primjena isključivo onih otopina koje ne sadrže čestice.
English: The exact reason why you have been prescribed ETOPOPHOS and associated names is best discussed with your doctor.
Croatian: O pravom razlogu zašto Vam je propisan ETOPOPHOS i pridružena imena, najbolje se obratiti svom liječniku.
English: The hydroxyacid metabolite [4' dimethyl-epipodophyllic acid-9-(4,6 0-ethylidene-β-Dglucopyranoside)], formed by opening of the lactone ring, is found in the urine of adults and children.
Croatian: Metabolit hidroksi kiseline [4'-dimetil-epipodofilna kiselina-9-(4,6-0-etiliden-β-D-glukopiranozid)], nastao otvaranjem laktonskog prstena, nađen je u urinu odraslih i djece.
English: - if you are taking any drugs with a similar mechanism of action as ETOPOPHOS and associated names.
Croatian: - ako uzimate bilo kakve lijekove sličnog mehanizma djelovanja kao ETOPOPHOS i pridružena imena.
English: • reactions at the site of infusion
Croatian: • reakcije na mjestu infuzije
English: ETOPOPHOS and associated names will be given to you by a doctor or nurse.
Croatian: ETOPOPHOS i pridružena imena davat će Vam liječnik ili medicinska sestra.
English: Anaphylactic reactions (see section 4.4), manifested by chills, tachycardia, bronchospasm, dyspnoea, diaphoresis, pyrexia, pruritus, hypertension or hypotension, syncope, nausea, and vomiting have been reported to occur in 3% (7 of 245 patients treated with ETOPOPHOS and associated names in 7 clinical studies) of patients treated with ETOPOPHOS and associated names.
Croatian: Anafilaktičke reakcije (vidjeti dio 4.4), koje se manifestiraju zimicom, tahikardijom, bronhospazmom, dispnejom, dijaforezom, pireksijom, pruritusom, hipertenzijom ili hipotenzijom, sinkopom, mučninom i povraćanjem prijavljene su u 3% (7 od 245 bolesnika liječenih ETOPOPHOSOM i pridruženim imenima u 7 kliničkih ispitivanja) bolesnika liječenih ETOPOPHOSOM i pridruženim imenima.
English: In clinical studies in which ETOPOPHOS and associated names was administered as a single agent at a total dose of ≥450 mg/m2 the most frequent adverse reactions of any severity were leucopenia (91%), neutropenia (88%), anaemia (72%) thrombocytopenia (23%), asthenia (39%), nausea and/or vomiting (37%), alopecia (33%) and chills and/or fever (24%).
Croatian: U kliničkim ispitivanjima u kojima se ETOPOPHOS i pridružena imena primjenjivao kao monoterapija u ukupnoj dozi od ≥ 450 mg/m2, najčešće nuspojave bilo kojeg stupnja težine bile su leukopenija (91%), neutropenija (88%), anemija (72%) trombocitopenija (23%), astenija (39%), mučnina i/ili povraćanje (37%), alopecija (33%) i zimica i/ili vrućica (24%).
English: A decision must be made whether to discontinue breast-feeding or to discontinue ETOPOPHOS and associated names, taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman (see section 4.3).
Croatian: Potrebno je odlučiti hoće li se prekinuti dojenje ili prekinuti liječenje ETOPOPHOSOM i pridruženim imenima, uzimajući pritom u obzir korist dojenja za dijete i korist terapije za majku (vidjeti dio 4.3).
English: There are no or limited amount of data from the use of etoposide phosphate in pregnant women.
Croatian: Ne postoje ili su ograničeni podaci o primjeni etopozidfosfata u trudnica.
English: If clinically significant hypertension occurs in patients receiving etoposide phosphate, appropriate supportive therapy should be initiated.
Croatian: Ako dođe do klinički značajne hipertenzije u bolesnika koji primaju etopozidfosfat, treba započeti odgovarajuću suportivnu terapiju.
English: Effect of etoposide phosphate on the pharmacokinetics of other drugs
Croatian: Učinak etopozidfosfata na farmakokinetiku drugih lijekova
English: Acute fatal reactions associated with bronchospasm have also been reported with etoposide phosphate.
Croatian: Akutne smrtonosne reakcije povezane s bronhospazmom, također su prijavljene s etopozidfosfatom.
English: Apnoea with spontaneous resumption of breathing following cessation of infusion have also been reported.
Croatian: Također je prijavljena apneja sa spontanim povratom disanja nakon prekida davanja infuzije.
English: Hypotension usually responds to cessation of infusion of etoposide phosphate and/or other supportive therapy as appropriate.
Croatian: Hipotenzija obično reagira na prestanak davanja infuzije etopozidfosfata i/ili na drugu suportivnu terapiju, prema potrebi.
English: The predominant macromolecular effect of etoposide seems to be the rupture of the double strand by an interaction with DNAtopoisomerase II or by the formation of free radicals.
Croatian: Čini se da je glavni makromolekularni učinak etopozida taj što izaziva pucanja dvostruke uzvojnice DNK interakcijom s DNK topoizomerazom II ili stvaranjem slobodnih radikala.
English: The stock solution should be withdrawn under aseptic conditions according to the physician's prescription and transferred to the infusion bottles and/or syringes for the individual patients.
Croatian: Rekonstituiranu otopinu treba izvlačiti u aseptičkim uvjetima, u skladu s liječničkim receptom i premjestiti u infuzijske boce i/ili štrcaljke za pojedine bolesnike.
English: At decreased creatinine clearance of 15 to 50 mL/min a dose reduction by 25% is recommended.
Croatian: Kod sniženog klirensa kreatinina od 15 do 50 ml/min, preporučuje se smanjenje doze za 25 %.
English: ETOPOPHOS and associated names is a white to off-white dry powder.
Croatian: ETOPOPHOS i pridružena imena je bijeli do gotovo bijeli suhi prašak.
English: Severe liver, kidney or heart damage from a condition called tumour lysis syndrome, caused by harmful amounts of substances from the cancer cells getting into the blood stream, has been seen sometimes when ETOPOPHOS and associated names is taken along with other drugs used to treat cancer.
Croatian: Teško oštećenje jetre, bubrega ili srca uzrokovano stanjem pod nazivom sindrom lize tumora, nastalog pod utjecajem štetnih količina tvari iz stanica raka koje uđu u krvotok, ponekad je opaženo kada se ETOPOPHOS i pridružena imena uzima zajedno s drugim lijekovima za liječenje raka.
English: ETOPOPHOS and associated names SHOULD NOT BE GIVEN BY RAPID INTRAVENOUS INJECTION.
Croatian: ETOPOPHOS i pridružena imena NE SMIJE SE DAVATI BRZOM INTRAVENSKOM INJEKCIJOM.
English: Solutions should be prepared under aseptic conditions.
Croatian: Otopine treba pripremati u aseptičkim uvjetima.
English: Both male patients and female patients of child-bearing age should use an effective contraceptive method (e.g., the barrier method or condoms) during treatment and for at least 6 months after the end of treatment with ETOPOPHOS and associated names.
Croatian: I muški i ženski bolesnici u reproduktivnoj dobi trebaju uzimati učinkovitu kontracepciju (npr. barijerna metoda ili kondomi) tijekom liječenja i najmanje 6 mjeseci nakon kraja liječenja ETHOPOSOM i pridruženim imenima.
English: ETOPOPHOS and associated names should not be physically mixed with any other drug.
Croatian: ETOPOPHOS i pridružena imena ne smiju se fizički miješati ni s jednim drugim lijekom.
English: No dosage adjustment is necessary in elderly patients (age > 65 years old), other than based on renal function.
Croatian: Nije potrebna prilagodba doze za starije bolesnike (u dobi od > 65 godina), osim na osnovi bubrežne funkcije.
English: In clinical studies involving etoposide phosphate, episodes of hypertension have been reported.
Croatian: U kliničkim ispitivanjima koja uključuju etopozidfosfat, prijavljene su epizode hipertenzije.
English: ****Postmarketing complications reported for extravasation included local soft tissue toxicity, swelling, pain, cellulitis, and necrosis including skin necrosis.
Croatian: **** Komplikacije ekstravazacije prijavljene nakon stavljanja lijeka u promet uključivale su lokalnu toksičnost za meko tkivo, oticanje, bol, celulitis i nekrozu, uključujući nekrozu kože.
English: In a study of the effects of other therapeutic agents on in vitro binding of 14C etoposide to human serum proteins, only phenylbutazone, sodium salicylate, and aspirin displaced protein-bound etoposide at concentrations generally achieved in vivo (see section 4.5).
Croatian: U ispitivanju učinaka drugih terapijskih sredstava na in vitro vezivanje 14C etopozida za proteine u ljudskom serumu, samo su fenilbutazon, natrijev salicilat i aspirin istisnuli etopozid vezan za proteine pri koncentracijama koje se općenito postižu in vivo (vidjeti dio 4.5).
English: ETOPOPHOS and associated names solutions must be prepared under aseptic conditions.
Croatian: ETOPOPHOS i pridružena imena moraju se pripremati u aseptičkim uvjetima.
English: Before use the content of each vial must be reconstituted with 5 ml or 10 ml of:
Croatian: Prije primjene, sadržaj svake bočice mora se rekonstituirati s 5 ml ili 10 ml:
English: Etoposide phosphate is administered by slow intravenous infusion (usually over a 30 to 60 minute period) (see section 4.4).
Croatian: Etopozidfosfat primjenjuje se sporom intravenskom infuzijom (obično u trajanju od 30 do 60 minuta) (vidjeti dio 4.4).
English: Transient hypotension following rapid intravenous administration has been reported in patients treated with etoposide phosphate and has not been associated with cardiac toxicity or electrocardiographic changes.
Croatian: Prolazna hipotenzija nakon brze intravenske primjene prijavljena je u bolesnika liječenih etopozidfosfatom i nije bila povezana sa srčanom toksičnošću ni elektrokardiografskim promjenama.
English: ETOPOPHOS and associated names 1000 mg is intended to be handled by pharmaceutical staff in central hospital units for the preparation of cytostatics.
Croatian: ETOPOPHOS i pridružena imena 1000 mg namijenjen je za rukovanje od strane farmaceutskog osoblja u središnjim bolničkim jedinicama za pripremu citostatika.
English: Male patients treated with ETOPOPHOS and associated names are advised not to father a child during treatment and for up to 6 months after treatment.
Croatian: Muškim bolesnicima liječenima ETOPOPHOSOM i pridruženim imenima, savjetuje se da ne začnu dijete tijekom liječenja i do 6 mjeseci nakon liječenja.
English: As etoposide phosphate is converted in vivo to etoposide by phosphorylation, caution should be exercised when administering etoposide phosphate with drugs that are known to inhibit phosphatase activity as such combination may reduce efficacy of etoposide phosphate.
Croatian: Budući da etopozidfosfat prelazi in vivo u etopozid procesom fosforilacije, potreban je oprez kod primjene etopozidfosfata s lijekovima za koje je poznato da inhibiraju aktivnost fosfataze, jer takva kombinacija može smanjiti djelotvornost etopozidfosfata.
English: In all instances where the use of ETOPOPHOS and associated names is considered for chemotherapy, the physician must evaluate the need and usefulness of the drug against the risk of adverse reactions.
Croatian: U svim slučajevima kada se za kemoterapiju razmatra primjena ETOPOPHOSA i pridruženih imena, liječnik mora procijeniti potrebu i korist lijeka u odnosu na rizik od nuspojava.
English: Total doses of 2.4 g/m to 3.5 g/m administered intravenously over three days have resulted in severe mucositis and myelotoxicity.
Croatian: Ukupne doze od 2,4 g/m2 do 3,5 g/m2 primijenjene intravenski tijekom tri dana uzrokovale su teški mukozitis i mijelotoksičnost.
English: These adverse reactions are presented by system organ class and frequency, which is defined by the following categories: very common (≥1/10), common (≥1/100, <1/10), uncommon (≥1/1, 000, <1/100), rare (≥1/10, 000, <1/1,000), not known (cannot be estimated from the available data).
Croatian: <1/10), manje često (≥1/1000, <1/100), rijetko (≥1/10 000, <1/1000), nepoznato (učestalost se ne može procijeniti iz dostupnih podataka).
English: ETOPOPHOS and associated names should not be used during pregnancy unless the clinical condition of the woman requires treatment with etoposide.
Croatian: ETOPOPHOS i pridružena imena ne smije se primjenjivati u trudnoći osim ako kliničko stanje žene ne zahtijeva liječenje etopozidom.
English: High dose ciclosporin, resulting in plasma concentrations above 2000 ng/mL, administered with oral etoposide has led to an 80% increase in etoposide exposure (AUC) with a 38% decrease in total body clearance of etoposide compared to etoposide alone.
Croatian: Visoka doza ciklosporina koja uzrokuje koncentracije u plazmi iznad 2000 ng/ml, primijenjena s oralnim etopozidom, dovela je do 80%-tnog povećanja izloženosti etopozidu (AUC) s 38%-tnim smanjenjem ukupnog tjelesnog klirensa etopozida u usporedbi s monoterapijom etopozidom.
English: Co-administration of antiepileptic drugs and ETOPOPHOS and associated names can lead to decreased seizure control due to pharmacokinetic interactions between the drugs.
Croatian: Istodobna primjena antiepileptičkih lijekova i ETOPOPHOSA i pridruženih imena može dovesti do smanjenja kontrole napadaja zbog farmakokinetičkih interakcija između tih lijekova.
English: • skin problems such as itching or rash
Croatian: • problemi s kožom poput svrbeža ili osipa
English: Hepatobiliary disorders very common alanine aminotransferase increased, alkaline phosphatase increased, aspartate amino transferase increased, bilirubin increased, hepatotoxicity
Croatian: Poremećaji jetre i žuči vrlo često povišena alanin aminotransferaza, povišena alkalna fosfataza, povišena aspartat aminotransferaza, povišen bilirubin, hepatotoksičnost
English: Hodgkin's lymphoma; non-Hodgkin's lymphoma; acute myeloid leukaemia
Croatian: Hodgkinov limfom; Non-Hodgkinov limfom; akutna mijeloična leukemija
English: • bleeding Rare side effects (affecting between 1 in 1,000 and 1 in 10,000 people)
Croatian: • krvarenje Rijetke nuspojave (mogu se javiti kod između 1 na 1000 i 1 na 10 000 osoba)
English: 6.6 Special precautions for disposal and other handling Procedures for proper handling and disposal of anti-cancer drugs should be followed.
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom Potrebno je slijediti procedure za pravilno rukovanje i zbrinjavanje antitumorskih lijekova.
English: For children being treated for cancer of the blood or lymphatic system the dose used is 75 to 150 mg/m2 body surface area daily for 2 to 5 days.
Croatian: Za djecu liječenu od raka krvi ili limfnog sustava, koristi se doza od 75 do 150 mg/m2 površine tijela dnevno tijekom 2 do 5 dana.
English: ETOPOPHOS and associated names must not be used during pregnancy unless clearly indicated by your doctor.
Croatian: ETOPOPHOS i pridružena imena ne smiju se koristiti tijekom trudnoće osim ako to jasno ne odredi
English: Leucopenia and severe leucopenia (less than 1,000 cells/mm3) were observed in 91% and 17%, respectively, for etoposide phosphate.
Croatian: Leukopenija i teška leukopenija (manje od 1000 stanica/mm3) zabilježene su kod 91%, odnosno 17% bolesnika, za etopozidfosfat.
English: It is supplied in a glass vial with a butyl rubber stopper and flip-off aluminium seal.
Croatian: Pakiran je u staklenu bočicu s čepom od butilne gume i aluminijskim zatvaračem.
English: Reinstitution of ETOPOPHOS and associated names therapy should be carried out with caution, and with adequate consideration of the further need for the drug and close attention to possible recurrence of toxicity.
Croatian: Ponovno uvođenje ETOPOPHOSA i pridruženih imena treba provoditi oprezno i uz odgovarajuće razmatranje dalje potrebe za lijekom te oprez zbog moguće ponovne pojave toksičnosti.
English: The name of this medicine is ETOPOPHOS and associated names.
Croatian: Naziv ovog lijeka je ETOPOPHOS i pridružena imena.
English: Anaphylactic reactions have been reported to occur during or immediately after intravenous administration of etoposide phosphate.
Croatian: Prijavljena je pojava anafilaktičkih reakcija tijekom ili neposredno nakon intravenske primjene etopozidfosfata.
English: Reports of fever and infection were also very common in patients with neutropenia treated with etoposide phosphate.
Croatian: Prijave vrućice i infekcije također su bile vrlo česte u bolesnika s neutropenijom liječenih etopozidfosfatom.
English: Ovarian cancer; small cell lung cancer; gestational trophoblastic neoplasia; testicular cancer
Croatian: Rak jajnika; rak pluća malih stanica; gestacijska trofoblastična neoplazija; rak testisa
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT [To be completed nationally]
Croatian: SADRŽAJ PO TEŽINI, VOLUMENU ILI DOZNOJ JEDINICI LIJEKA [Ispunjava država članica]
English: What you need to know before you are given ETOPOPHOS and associated names
Croatian: Što morate znati prije nego počnete primati ETOPOPHOS i pridružena imena
English: • sore lips, mouth or throat ulcers
Croatian: • bolne usne, rancie u ustima ili grlu
English: Dextran 40 [To be completed nationally]
Croatian: Dekstran 40 [Ispunjava država članica]
English: Etoposide phosphate may cause adverse reactions that affect the ability to drive or use machines such as fatigue, somnolence, nausea, vomiting, cortical blindness, hypersensitivity reactions with hypotension.
Croatian: Etopozidfosfat može uzrokovati nuspojave koje utječu na sposobnost upravljanja vozilima i rada sa strojevima, poput umora, somnolencije, mučnine, povraćanja, kortikalne sljepoće, reakcija preosjetljivosti s hipotenzijom.
English: These reactions have usually responded promptly to the cessation of the infusion and administration of pressor agents, corticosteroids, antihistamines, or volume expanders as appropriate.
Croatian: Te reakcije obično su brzo reagirale na prekid davanja infuzije i primjenu presornih lijekova, kortikosteroida, antihistaminika ili ekspandera volumena, prema potrebi.
English: How to store ETOPOPHOS and associated names Contents of the pack and other information
Croatian: Kako čuvati ETOPOPHOS i pridružena imena Sadržaj pakiranja i druge informacije
English: Etoposide phosphate is metabolised in vivo into the active substance etoposide by a process of dephosphorylation.
Croatian: Etopozidfosfat metabolizira se in vivo u djelatnu tvar etopozid procesom defosforilacije.
English: If you are given more ETOPOPHOS and associated names than you should
Croatian: Ako ste primili više lijeka ETOPOPHOS i pridružena imena nego što ste trebali
English: Doses subsequent to initial dose should be adjusted if neutrophil count less than 500 cells/mm3 occurs for more than 5 days or is associated with fever or infection, if platelet count less than 25,000 cells/mm3 occurs, if any grade 3 or 4 toxicity develops or if renal clearance is less than 50 ml/min.
Croatian: Doze koje se primjenjuju nakon početne doze treba prilagoditi ako je broj neutrofila manji od 500 stanica/mm3 tijekom više od 5 dana ili je povezan s vrućicom ili infekcijom, ako broj trombocita padne na manje od 25 000 stanica/mm3 ili ako se razvije toksičnost 3. ili 4. stupnja ili ako je bubrežni klirens manji od 50 ml/min.
English: Do not use this medicine after the expiry date which is stated on the carton and vial after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici nakon oznake „Rok valjanosti“ ili „EXP“.
English: Nervous system disorders common dizziness uncommon neuropathy peripheral rare cortical blindness transient, neurotoxicities (e.g., somnolence and fatigue), optic neuritis, seizure***
Croatian: Poremećaji živčanog sustava često omaglica manje često periferna neuropatija rijetko prolazna kortikalna sljepoća, neurotoksičnosti (npr., somnolencija i umor), optički neuritis, napadaj***
English: Physicians should be aware of the possible occurrence of an anaphylactic reaction with ETOPOPHOS and associated names, manifested by chills, pyrexia, tachycardia, bronchospasm, dyspnoea and hypotension, which can be fatal.
Croatian: Liječnici moraju biti svjesni mogućnosti nastupa anafilaktičke reakcije na ETOPOPHOS i pridružena imena, čiji su znakovi zimica, vrućica, tahikardija, bronhospazam, dispneja i hipotenzija, koja može imati smrtni ishod.
English: The stopper of the vial should be pierced only once and a sterile transfusion set or any other auxiliary device should be used for withdrawal for the solution.
Croatian: Čep bočice smije se probušiti samo jednom, a za izvlačenje otopine treba koristiti sterilni komplet za transfuziju ili neki drugi pomoćni uređaj.
English: This will yield a reconstituted stock solution containing 20 mg/ml or 10 mg/ml etoposide.
Croatian: To će dati zalihu rekonstituirane otopine koja sadrži 20 mg/ml ili 10 mg/ml etopozida.
English: Patients being treated with ETOPOPHOS and associated names must be observed for myelosuppression carefully and frequently both during and after therapy.
Croatian: Bolesnike koji se liječe ETOPOPHOSOM i pridruženim imenima mora se pažljivo i često kontrolirati i tijekom i nakon terapije zbog moguće mijelosupresije.
English: Since etoposide and its metabolites are not dialyzable, it can be administered pre- and post-haemodialysis (see section 4.9).
Croatian: Budući da se etopozid i njegovi metaboliti ne mogu dijalizirati, može se primijeniti prije i nakon hemodijalize (vidjeti dio
English: Concomitant phenytoin therapy is associated with increased etoposide clearance and reduced efficacy, and other enzyme-inducing antiepileptic therapy may be associated with increased ETOPOPHOS and associated names clearance and reduced efficacy.
Croatian: Istodobno liječenje fenitoinom povezano je s povećanim klirensom etopozida i smanjenom djelotvornošću, a liječenje drugim antiepilepticima koji induciraju enzime može biti povezano s povećanjem klirensa ETOPOPHOSA i pridruženih imena te smanjenom djelotvornošću.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each vial contains 113.6 mg etoposide phosphate equivalent to 100 mg etoposide.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedna bočica sadrži 113,6 mg etopozidfosfata, što odgovara 100 mg etopozida.
English: Testicular cancer
Croatian: Rak testisa
English: The doses after the initial dose should be adjusted if neutrophil count is below 500 cells/mm3 for more than 5 days.
Croatian: Doze nakon početne doze treba prilagoditi ako je broj neutrofila manji od 500 stanica/mm3 tijekom više od 5 dana.
English: Dosage should be modified to take into account the myelosuppressive effects of other drugs in the combination or the effects of prior radiotherapy or chemotherapy (see section 4.4) which may have compromised bone marrow reserve.
Croatian: Dozu treba modificirati kako bi se uzeli u obzir mijelosupresivni učinci drugih lijekova u kombinaciji ili učinci prethodne radioterapije ili kemoterapije (vidjeti dio 4.4), koji su mogli oštetiti rezervu koštane srži.
English: Other medicines and ETOPOPHOS and associated names
Croatian: Drugi lijekovi i ETOPOPHOS i pridružena imena