FrancophonIA/ELRC3.0 huggingface dataset:
English: It is recommended that alternative administration forms should be considered for concomitant treatment of concurrent diseases that can be treated via nasal administration.
Romanian: În cazul tratamentului concomitent al afecţiunilor concomitente care pot fi tratate prin administrare pe cale nazală este recomandabil să fie luate în considerare formele alternative de administrare.
English: The other ingredients are sodium dihydrogen phosphate dihydrate, disodium phosphate dihydrate, and water for injections.
Romanian: Celelalte componente sunt dihidrogenofosfat de sodiu dihidrat, fosfat disodic dihidrat şi apă pentru preparate injectabile.
English: A polypropylene (PP) nasal spray container consisting of a glass bottle (brown Type 1 glass) with metering pump.
Romanian: Recipient sub formă de flacon (din sticlă brună tip I) integrat într-un recipient spray de polipropilenă, cu pompă dozatoare.
English: o That for the multi-dose nasal spray and multi-dose nasal spray DoseGuard all unused devices or empty containers should be returned systematically according to the local regulation.
Romanian: - Pentru spray-ul nazal multidoză şi spray-ul nazal multidoză DoseGuard toate flacoanele neutilizate sau goale trebuie returnate sistematic în conformitate cu legislaţia locală.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 50 micrograms/dose nasal spray, solution Instanyl 100 micrograms/dose nasal spray, solution Instanyl 200 micrograms/dose nasal spray, solution
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 50 micrograme/doză spray nazal, soluţie Instanyl 100 micrograme/doză spray nazal, soluţie Instanyl 200 micrograme/doză spray nazal, soluţie
English: 100 micrograms/dose labelling is purple.
Romanian: 100 micrograme/doză - etichetarea este roşu închis
English: Maintenance therapy
Romanian: Abordare terapeutică
English: The other ingredients are sodium dihydrogen phosphate dihydrate, disodium phosphate dihydrate, and purified water.
Romanian: Celelalte componente sunt dihidrogenofosfat de sodiu dihidrat, fosfat disodic dihidrat şi apă purificată
English: To re-attach, place the child-resistant cap on the nasal spray and turn the cap clockwise.
Romanian: Pentru a-l reataşa, puneţi capacul fără filet cu sistem de închidere securizat pentru copii pe spray-ul nazal şi rotiţi-l în sens orar.
English: Keep the bottle stored upright.
Romanian: A se păstra flaconul menţinut în poziţie verticală.
English: What Instanyl looks like and contents of the pack Instanyl is a nasal spray, solution in a single-dose spray container.
Romanian: Instanyl este un spray nazal, sub formă de soluţie într-un recipient unidoză.
English: Bottle (brown Type 1 glass) with metering pump and dust cap packed in a child-resistant outer box.
Romanian: 6.5 Natura şi conţinutul ambalajului Flacon (din sticlă brună Tip 1) prevăzut cu pompă dozatoare şi capac de protecţie ambalate într-o cutie cu sistem de închidere securizat pentru copii.
English: Any used or unused nasal spray should be returned systematically and suitably in the child-resistant outer box and discarded according to local requirements or returned to the pharmacy.
Romanian: Toate spray-urile nazale utilizate sau neutilizate trebuie reintroduse în mod sistematic şi corespunzător în cutia cu sistem de închidere securizat pentru copii şi eliminate sistematic în conformitate cu reglementările locale sau returnate la farmacie.
English: • For the single-dose nasal spray all unused devices or empty containers should be returned systematically according to the local regulation.
Romanian: - Pentru spray-ul nazal unidoză toate flacoanele neutilizate sau recipientele goale trebuie returnate sistematic în conformitate cu legislaţia locală.
English: 200 micrograms: 1 dose (100 microlitres) contains fentanyl citrate equivalent to 200 micrograms fentanyl.
Romanian: 200 micrograme: 1 doză (100 microlitri) conţine citrat de fentanil echivalent cu fentanil 200 micrograme.
English: • Instanyl nasal spray is only indicated for the management of breakthrough pain in adults already receiving maintenance opioid therapy for chronic cancer pain.
Romanian: - Instanyl spray nazal este indicat pentru controlul durerii episodice intense la adulţii cărora li se administrează deja tratament de întreţinere cu opioide pentru durerea cronică din afecţiunile neoplazice.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 50 micrograms nasal spray Fentanyl
Romanian: Instanyl 50 de micrograme spray nazal Fentanil
English: If you have not used Instanyl for more than 7 days the pump must be primed again by spraying once before the next dose is taken.
Romanian: Dacă nu s-a utilizat Instanyl timp de mai mult de 7 zile, se va amorsa pompa dozatoare o dată în aer înainte de a administra următoarea doză.
English: Treatment
Romanian: Tratamentul de întreţinere
English: Also contains: sodium dihydrogen phosphate dihydrate, disodium phosphate dihydrate, water for injections
Romanian: LISTA EXCIPIENŢILOR Conţine de asemenea: dihidrogenofosfat de sodiu dihidrat, fosfat disodic dihidrat, apă pentru preparate injectabile
English: Instanyl 50 micrograms/dose nasal spray, solution Each ml of solution contains fentanyl citrate equivalent to 500 micrograms fentanyl.
Romanian: Instanyl 50 micrograme/doză spray nazal, soluţie Fiecare ml de soluţie conţine citrat de fentanil echivalent cu fentanil 500 micrograme.
English: Instanyl 200 micrograms/dose nasal spray, solution Each ml of solution contains fentanyl citrate equivalent to 2,000 micrograms fentanyl.
Romanian: Instanyl 200 micrograme/doză spray nazal, soluţie Fiecare ml de soluţie conţine citrat de fentanil echivalent cu fentanil 2000 micrograme.
English: 2.0 ml containing 2.00 mg fentanyl ensuring the delivery of 10 doses of 100 micrograms 3.2 ml containing 3.20 mg fentanyl ensuring the delivery of 20 doses of 100 micrograms 4.3 ml containing 4.30 mg fentanyl ensuring the delivery of 30 doses of 100 micrograms 5.3 ml containing 5.30 mg fentanyl ensuring the delivery of 40 doses of 100 micrograms
Romanian: 2,0 ml conţinând fentanil 2,00 mg asigurând eliberarea a 10 doze a câte 100 micrograme 3,2 ml conţinând fentanil 3,20 mg asigurând eliberarea a 20 doze a câte 100 micrograme 4,3 ml conţinând fentanil 4,30 mg asigurând eliberarea a 30 doze a câte 100 micrograme 5,3 ml conţinând fentanil 5,30 mg asigurând eliberarea a 40 doze a câte 100 micrograme
English: 1 puff (100 microlitres) contains 200 micrograms fentanyl.
Romanian: 1 puf (100 microlitri) conţine fentanil 200 micrograme.
English: Instanyl 100 micrograms/dose nasal spray, solution Each ml of solution contains fentanyl citrate equivalent to 1,000 micrograms fentanyl.
Romanian: Instanyl 100 micrograme/doză spray nazal, soluţie Fiecare ml de soluţie conţine citrat de fentanil echivalent cu fentanil 1000 micrograme.
English: 2.0 ml containing 1.00 mg fentanyl ensuring the delivery of 10 doses of 50 micrograms 3.2 ml containing 1.60 mg fentanyl ensuring the delivery of 20 doses of 50 micrograms 4.3 ml containing 2.15 mg fentanyl ensuring the delivery of 30 doses of 50 micrograms 5.3 ml containing 2.65 mg fentanyl ensuring the delivery of 40 doses of 50 micrograms
Romanian: 2,0 ml conţinând fentanil 1,00 mg asigurând eliberarea a 10 doze a câte 50 micrograme 3,2 ml conţinând fentanil 1,60 mg asigurând eliberarea a 20 doze a câte 50 micrograme 4,3 ml conţinând fentanil 2,15 mg asigurând eliberarea a 30 doze a câte 50 micrograme 5,3 ml conţinând fentanil 2,65 mg asigurând eliberarea a 40 doze a câte 50 micrograme
English: 1 ml contains fentanyl citrate equivalent to 1,000 micrograms fentanyl.
Romanian: 1 ml de soluţie conţine citrat de fentanil echivalent cu fentanil 1000 micrograme.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 200 micrograms nasal spray Fentanyl
Romanian: Instanyl 200 de micrograme spray nazal Fentanil
English: Instanyl 50 micrograms/dose nasal spray, solution.
Romanian: Instanyl 50 micrograme/doză spray nazal, soluţie.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CHILD-RESISTANT OUTER BOX (Multi dose)
Romanian: CUTIE SISTEM DE ÎNCHIDERE SECURIZAT PENTRU COPII (Multidoză)
English: NAME OF THE MEDICINAL PRODUCT Instanyl 100 micrograms nasal spray Fentanyl
Romanian: Instanyl 100 de micrograme spray nazal Fentanil
English: 1 dose (100 microlitres) contains 200 micrograms fentanyl.
Romanian: 1 doză (100 microlitri) conţine fentanil 200 micrograme.
English: Instanyl 50 micrograms/dose nasal spray, solution
Romanian: Instanyl 50 micrograme/doză spray nazal, soluţie
English: Instanyl should be administered with caution to patients with moderate to severe hepatic impairment (see section 4.4).
Romanian: Instanyl trebuie administrat cu precauţie la pacienţii cu insuficienţă hepatică moderată până la severă
English: 1.8 ml containing 1.80 mg fentanyl ensuring the delivery of 10 doses of 100 micrograms 2.9 ml containing 2.90 mg fentanyl ensuring the delivery of 20 doses of 100 micrograms 5.0 ml containing 5.00 mg fentanyl ensuring the delivery of 40 doses of 100 micrograms
Romanian: 1,8 ml conţinând fentanil 1,80 mg asigurând eliberarea a 10 doze a câte 100 micrograme 2,9 ml conţinând fentanil 2,90 mg asigurând eliberarea a 20 doze a câte 100 micrograme 5,0 ml conţinând fentanil 5,00 mg asigurând eliberarea a 40 doze a câte 100 micrograme
English: Dose titration
Romanian: Stabilirea treptată a dozei
English: 1 dose of 100 microlitres equals 200 micrograms fentanyl.
Romanian: 1 doză de 100 microlitri este echivalentă cu fentanil 200 micrograme.
English: 1 dose of 100 microlitres equals 100 micrograms fentanyl.
Romanian: 1 doză de 100 microlitri este echivalentă cu 100 micrograme fentanil.
English: 1.8 ml containing 0.90 mg fentanyl ensuring the delivery of 10 doses of 50 micrograms 2.9 ml containing 1.45 mg fentanyl ensuring the delivery of 20 doses of 50 micrograms 5.0 ml containing 2.50 mg fentanyl ensuring the delivery of 40 doses of 50 micrograms
Romanian: 1,8 ml conţinând fentanil 0,90 mg asigurând eliberarea a 10 doze a câte 50 micrograme 2,9 ml conţinând fentanil 1,45 mg asigurând eliberarea a 20 doze a câte 50 micrograme 5,0 ml conţinând fentanil 2,50 mg asigurând eliberarea a 40 doze a câte 50 micrograme
English: NAME OF THE MARKETING AUTHORISATION HOLDER Takeda Pharma A/S
Romanian: Takeda Pharma A/S
English: Instanyl 200 micrograms/dose nasal spray, solution.
Romanian: Instanyl 200 micrograme/doză spray nazal, soluţie.
English: Instanyl 100 micrograms nasal spray, solution in single-dose container 3 years
Romanian: Instanyl 100 micrograme spray nazal, soluţie în recipient unidoză
English: 50 micrograms/dose: 1 ml contains fentanyl citrate equivalent to 500 micrograms fentanyl.
Romanian: 50 micrograme/doză: 1 ml de soluţie conţine citrat de fentanil echivalent cu fentanil 500 micrograme.
English: 1 dose (100 microlitres) contains fentanyl citrate equivalent to 200 micrograms (mcg) fentanyl
Romanian: 1 doză (100 microlitri) conţine citrat de fentanil echivalent cu fentanil 200 micrograme (µg)
English: NAME OF THE MEDICINAL PRODUCT Instanyl 50 micrograms nasal spray, solution in single-dose container Fentanyl
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 50 de micrograme spray nazal, soluţie în recipient unidoză
English: 50 micrograms: 1 dose (100 microlitres) contains fentanyl citrate equivalent to 50 micrograms fentanyl.
Romanian: 50 micrograme: 1 doză (100 microlitri) conţine citrat de fentanil echivalent cu fentanil 50 micrograme.
English: INFORMATION IN BRAILLE Instanyl 100
Romanian: Instanyl 100
English: Instanyl 50 micrograms nasal spray, solution in single-dose container Instanyl 100 micrograms nasal spray, solution in single-dose container Instanyl 200 micrograms nasal spray, solution in single-dose container fentanyl
Romanian: Prospect: Informații pentru utilizator Instanyl 50 micrograme spray nazal, soluţie în recipient unidoză Instanyl 100 micrograme spray nazal, soluţie în recipient unidoză Instanyl 200 micrograme spray nazal, soluţie în recipient unidoză fentanil
English: 200 micrograms/dose: 1 ml contains fentanyl citrate equivalent to 2,000 micrograms fentanyl.
Romanian: 200 micrograme/doză: 1 ml de soluţie conţine citrat de fentanil citrat echivalent cu fentanil 2000 micrograme.
English: 1 puff (100 microlitres) contains 100 micrograms fentanyl.
Romanian: 1 puf (100 microlitri) conţine fentanil 100 micrograme.
English: 1 puff (100 microlitres) contains 50 micrograms fentanyl.
Romanian: 1 puf (100 microlitri) conţine fentanil 50 micrograme.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 200 micrograms nasal spray, solution in single-dose container Fentanyl
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 200 de micrograme spray nazal, soluţie în recipient unidoză
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS INTERMEDIATE CHILD-RESISTANT BLISTER (Single dose)
Romanian: MINIMUM DE INFORMAŢII CARE TREBUIE SĂ APARĂ PE BLISTER SAU PE FOLIE TERMOSUDATĂ
English: 100 micrograms/dose: 1 ml contains fentanyl citrate equivalent to 1,000 micrograms fentanyl.
Romanian: 100 micrograme/doză: 1 ml de soluţie conţine citrat de fentanil echivalent cu 1000 micrograme fentanil.
English: Instanyl 50 micrograms/dose nasal spray, solution Instanyl 100 micrograms/dose nasal spray, solution Instanyl 200 micrograms/dose nasal spray, solution fentanyl
Romanian: Prospect: Informații pentru utilizator Instanyl 50 micrograme/doză spray nazal, soluţie Instanyl 100 micrograme/doză spray nazal, soluţie Instanyl 200 micrograme/doză spray nazal, soluţie fentanil
English: 1 dose (100 microlitres) contains 100 micrograms fentanyl.
Romanian: 1 doză (100 microlitri) conţine fentanil 100 micrograme.
English: 1 dose (100 microlitres) contains 50 micrograms fentanyl.
Romanian: 1 doză (100 microlitri) conţine fentanil 50 micrograme.
English: Instanyl is intended for nasal use only.
Romanian: Instanyl este indicat exclusiv pentru administrare pe cale nazală.
English: Gastrointestinal disorders
Romanian: Tulburări gastro-intestinale Greaţă, vărsături
English: INFORMATION IN BRAILLE Instanyl 200, single-dose
Romanian: Instanyl 200, unidoză
English: Instanyl 200 micrograms nasal spray, solution in single-dose container 42 months
Romanian: Instanyl 200 micrograme spray nazal, soluţie în recipient unidoză
English: Instanyl 100 micrograms/dose nasal spray, solution.
Romanian: Instanyl 100 micrograme/doză spray nazal, soluţie.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 50 micrograms nasal spray, solution in single-dose container Instanyl 100 micrograms nasal spray, solution in single-dose container Instanyl 200 micrograms nasal spray, solution in single-dose container
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 50 micrograme spray nazal, soluţie în recipient unidoză Instanyl 100 micrograme spray nazal, soluţie în recipient unidoză
English: NAME OF THE MEDICINAL PRODUCT Instanyl 50 micrograms/dose nasal spray, solution Fentanyl
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 50 de micrograme/doză spray nazal, soluţie
English: 3.2 ml containing 6.40 mg fentanyl ensuring the delivery of 20 doses of 200 micrograms 4.3 ml containing 8.60 mg fentanyl ensuring the delivery of 30 doses of 200 micrograms 5.3 ml containing 10.60 mg fentanyl ensuring the delivery of 40 doses of 200 micrograms
Romanian: 2,0 ml conţinând fentanil 4,00 mg asigurând eliberarea a 10 doze a câte 200 micrograme 3,2 ml conţinând fentanil 6,40 mg asigurând eliberarea a 20 doze a câte 200 micrograme 4,3 ml conţinând fentanil 8,60 mg asigurând eliberarea a 30 doze a câte 200 micrograme 5,3 ml conţinând fentanil 10,60 mg asigurând eliberarea a 40 doze a câte 200 micrograme
English: The primary therapeutic action is analgesia.
Romanian: Instanyl trebuie înlocuit cu alte analgezice.
English: Always place Instanyl in the child-resistant box after use.
Romanian: După utilizare, introduceţi întotdeauna Instanyl în cutia cu sistem de închidere securizat pentru copii.
English: NAME OF THE MEDICINAL PRODUCT Instanyl 200 micrograms/dose nasal spray, solution Fentanyl
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 200 de micrograme/doză spray nazal, soluţie
English: Instanyl 100 micrograms/dose nasal spray, solution
Romanian: Instanyl 100 micrograme/doză spray nazal, soluţie
English: 1 dose of 100 microlitres equals 50 micrograms fentanyl.
Romanian: 1 doză de 100 microlitri este echivalentă cu fentanil 50 micrograme.
English: • For the multi-dose nasal spray and multi-dose nasal spray DoseGuard all unused devices or empty containers should be returned systematically according to the local regulation.
Romanian: • Informaţiilor despre schema de numărare a dozei inclusă în etichetare şi în materialul educaţional pentru spray nazal multidoză - Pentru spray-ul nazal multidoză şi spray-ul nazal multidoză DoseGuard toate flacoanele neutilizate sau goale trebuie returnate sistematic în conformitate cu legislaţia locală.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER BOX - CARTON (Single Dose)
Romanian: CUTIE DIN CARTON (Unidoză)
English: NAME OF THE MEDICINAL PRODUCT Instanyl 100 micrograms/dose nasal spray, solution Fentanyl
Romanian: DENUMIREA COMERCIALĂ A MEDICAMENTULUI Instanyl 100 de micrograme/doză spray nazal, soluţie
English: What Instanyl looks like and contents of the pack Instanyl is a nasal spray, solution.
Romanian: FORMA FARMACEUTICĂ ŞI CONŢINUTUL Spray nazal, soluţie
English: Tel.: + 420 234 722 722
Romanian: Takeda Pharmaceuticals Czech Republic s.r.o. Tel.: + 420 234 722 722
English: NAME OF THE MEDICINAL PRODUCT Instanyl 100 micrograms nasal spray, solution in single-dose container Fentanyl
Romanian: Instanyl 100 de micrograme spray nazal, soluţie în recipient unidoză Fentanil
English: • Instructions for use of the nasal spray device.
Romanian: • Instrucţiunilor pentru utilizarea flaconului pulverizator
English: What Instanyl looks like and contents of the pack Instanyl DoseGuard is a nasal spray, solution.
Romanian: Instanyl DoseGuard este un spray nazal sub formă de soluţie.
English: • shows the number of doses left
Romanian: Un afişaj electronic care ° furnizează instrucţiuni privind numărul de acţionări pentru amorsare ° arată numărul de doze rămase
English: Instanyl 200 micrograms/dose nasal spray, solution 1.8 ml containing 3.60 mg fentanyl ensuring the delivery of 10 doses of 200 micrograms 2.9 ml containing 5.80 mg fentanyl ensuring the delivery of 20 doses of 200 micrograms 5.0 ml containing 10.00 mg fentanyl ensuring the delivery of 40 doses of 200 micrograms
Romanian: 1,8 ml conţinând fentanil 3,60 mg asigurând eliberarea a 10 doze a câte 200 micrograme 2,9 ml conţinând fentanil 5,80 mg asigurând eliberarea a 20 doze a câte 200 micrograme 5,0 ml conţinând fentanil 10,00 mg asigurând eliberarea a 40 doze a câte 200 micrograme
English: INFORMATION IN BRAILLE Instanyl 100, single-dose
Romanian: Instanyl 100, unidoză
English: 1 ml contains fentanyl citrate equivalent to 500 micrograms fentanyl.
Romanian: DECLARAREA SUBSTANŢEI(LOR) ACTIVE 1 ml de soluţie conţine citrat de fentanil echivalent cu fentanil 500 micrograme.
English: Flushing, hot flush
Romanian: ameţeli, cefalee
English: Instanyl with food, drink and alcohol
Romanian: SERIA DE FABRICAŢIE<, CODURILE DONAŢIEI ŞI MEDICAMENTULUI>
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT 1 dose
Romanian: Pentru administrare pe cale nazală 1 doză
English: Close one nostril by placing your finger against the side of your nose and insert the spray tip into the other nostril (approximately 1 cm).
Romanian: Ţineţi spray-ul nazal în poziţie verticală; 5. Aplecaţi-vă capul uşor înainte; 6. Acoperiţi o nară apăsând cu degetul pe partea laterală a nasului şi introduceţi vârful spray-ului în cealaltă nară (aproximativ 1 cm).
English: 1 ml contains fentanyl citrate equivalent to 2,000 micrograms fentanyl.
Romanian: DECLARAREA SUBSTANŢEI(LOR) ACTIVE 1 ml de soluţie conţine citrat de fentanil echivalent cu fentanil 2000 micrograme.
English: 100 micrograms: 1 dose (100 microlitres) contains fentanyl citrate equivalent to 100 micrograms fentanyl.
Romanian: 100 micrograme: 1 doză (100 microlitri) conţine citrat de fentanil echivalent cu fentanil
English: Dose linearity from 50 micrograms to 400 micrograms of Instanyl has been demonstrated in healthy subjects.
Romanian: Instanyl de la 50 micrograme la 400 micrograme.
English: Instanyl should be administered with caution to patients with moderate to severe renal impairment (see section 4.4).
Romanian: Insuficienţă renală Instanyl trebuie administrat cu precauţie la pacienţii cu insuficienţă renală moderată până la severă
English: − A training course for neurosurgeons which is aimed at risk minimisation and to support safe and effective use for the product.
Romanian: − Un curs de pregătire pentru neurochirurgi, având drept scop reducerea la minimum a riscului şi utilizarea eficace a medicamentului.
English: IV); - Neurophysiological monitoring techniques for surgery in eloquent brain regions.
Romanian: - Tehnici de monitorizare neurofiziologică pentru chirurgia ariilor cerebrale de importanţă vitală.
English: III trial; - Experience with Gliolan-fluorescence-guided surgery in at least 20 cases.
Romanian: - Experienţă în chirurgia ghidată prin fluorescenţa indusă de Gliolan în cel puţin 20 de cazuri.
English: a) Theory and core principles of Gliolan-fluorescence-guided surgery and malignant glioma resection, including methods of eloquent sites identification; b) On-site instructions on the use of the fluorescence-microscope, including pitfalls and recognition of problems; c) Differentiation of fluorescence intensity, maintaining safety distances from eloquent areas, etc. d) The practice of Gliolan-fluorescence-guided surgery (including participation in at least one cases using Gliolan-fluorescence-guided surgery in the operating room with on-site instructions on the use of the microscope or demonstration of a fluorescence-guided resection by video); e) The current understanding of the benefits and risks of cytoreductive surgery in the management of patients with malignant gliomas; f) The theoretical base for porphyrin accumulation in malignant gliomas; g) The technical principles behind fluorescence-guided resections using Gliolan; h) How to identify suitable candidates for fluorescence-guided resections using Gliolan; i) How to apply Gliolan in the correct dosage and timing regimen, and to understand the importance of concurrent corticosteroids; j) How to identify patients at risk for neurological deficits using fluorescence-guided resections with Gliolan with special focus on aphasias and other critical focal deficits; k) Techniques for intraoperative risk reduction (microsurgical technique, neurophysiological monitoring, choice of approach) and how to implement them; l) How to identify fluorescence for resection through using the operating microscope in a handson setting in the operating room; m) The benefits and risks of fluorescence-guided resections using Gliolan;
Romanian: j) Identificarea pacienţilor cu risc de deficienţe neurologice utilizând rezecţiile ghidate prin fluorescenţă folosind Gliolan, cu accent deosebit pe afazii şi alte deficienţe focale grave; k) Tehnici de reducere a riscului intraoperator (tehnica de microchirurgie, monitorizarea neurofiziologică, alegerea abordării) şi modul de aplicare a acestora; l) Identificarea fluorescenţei pentru rezecţie folosind efectiv microscopul în sala de operaţie; m) Beneficiile şi riscurile rezecţiilor ghidate prin fluorescenţă folosind Gliolan.
English: Minimum requirements for a qualified training centre are: - Microscope modified for fluorescence-guided resection; - Sufficient case load (at least 10 patients per year) of malignant gliomas (WHO grade III and
Romanian: - Cazuistică suficientă (cel puţin 10 pacienţi pe an) de glioame maligne (gradul III şi IV OMS);
English: Minimum requirements for a qualified trainer are: - Board-certification as neurosurgeon according to local, national requirements; - Previous successful participation at a training course, or equivalent course during the phase
Romanian: - Promovarea anterioară a unui curs de pregătire sau a unui curs echivalent pe durata unui studiu clinic de fază III;
English: Other information about Ziagen:
Romanian: Alte informații despre Ziagen: