FrancophonIA/ELRC3.0 huggingface dataset:
English: Ziagen and similar medicines may cause side effects in unborn babies.
Danish: Ziagen og lignende medicin kan give fosteret bivirkninger.
English: It should be taken into account that data for the once daily regimen are very limited in this population (see sections 5.1 and 5.2).
Danish: Der skal tages højde for, at data vedrørende behandling med én daglig dosis er meget begrænsede hos denne population (se pkt.
English: In HIV-infected patients with severe immune deficiency at the time of initiation of combination antiretroviral therapy (CART) an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Danish: Hos hiv-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske infektioner.
English: Importantly, such symptoms may lead to misdiagnosis of HSR as respiratory disease (pneumonia, bronchitis, pharyngitis), or gastroenteritis .
Danish: Disse symptomer kan føre til fejldiagnosticering af overfølsomhed som respiratorisk sygdom (pneumoni, bronkitis, faryngitis) eller gastroenteritis.
English: Adults, adolescents and children (weighing at least 25 kg):
Danish: Voksne, unge og børn (som vejer mindst 25 kg):
English: Twice daily (300 mg) administration:
Danish: Administration 2 gange daglig (300 mg):
English: Patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities during combination antiretroviral therapy, and should be monitored according to standard practice.
Danish: Hos patienter med leverinsufficiens, herunder kronisk aktiv hepatitis, ses oftere abnorm leverfunktion i forbindelse med den antiretrovirale behandling, og disse patienter skal kontrolleres i henhold til standardpraksis.
English: -1.6% (95% CI -8.4% to +5.2%), p=0.65
Danish: -1,6 % (95 % CI -8.4 % - +5,2 %), p=0,65
English: A fertility study in the rat has shown that abacavir had no effect on male or female fertility.
Danish: Et fertilitetsstudie hos rotter viste, at abacavir ikke påvirkede hanlig eller hunlig fertilitet.
English: A 10 ml oral dosing syringe and a plastic adapter for the bottle are included in the pack.
Danish: Pakningen indeholder en 10 ml doseringssprøjte og et tilpasningsstykke i plastik til flasken.
English: -4.8% (95% CI -11.5% to +1.9%), p=0.16
Danish: -4,8 % (95 % CI -11,5 % - +1,9 %), p=0,16
English: The tablet coating contains triacetin, methylhydroxypropylcellulose, titanium dioxide, polysorbate 80 and iron oxide yellow.
Danish: Tabletovertræk: Triacetin, methylhydroxypropylcellulose, titandioxid, polysorbat 80 og gul jernoxid.
English: Since Ziagen contains abacavir some patients taking Ziagen may develop a hypersensitivity reaction (serious allergic reaction) which can be life-threatening if treatment with Ziagen is continued.
Danish: Da Ziagen indeholder abacavir kan nogle patienter, som tager Ziagen, få en overfølsomhedsreaktion (alvorlig allergisk reaktion), som kan være livstruende, hvis behandling med Ziagen fortsættes.
English: Children receiving abacavir oral tablets according to the recommended dosage regimen achieve higher plasma abacavir exposure than children receiving oral solution because higher mg/kg doses are administered with the tablet formulation.
Danish: Børn, som får abacavir-tabletter i henhold til doseringsanbefalingerne, opnår højere abacavir-plasmaniveauer end børn, som får oral opløsning, da der administreres højere mg/kg-doser med tabletformuleringen.
English: Other symptoms include:
Danish: Øvrige symptomer omfatter:
English: Methadone: in a pharmacokinetic study, co-administration of 600 mg abacavir twice daily with methadone showed a 35% reduction in abacavir Cmax and a one hour delay in tmax but the AUC was unchanged.
Danish: Et farmakokinetisk studie viste, at samtidig administration af 600 mg abacavir 2 gange daglig og methadon reducerede Cmax for abacavir med 35 % og udsatte tmax med en time, men AUC var uændret.
English: Read the information ‘Other possible side effects of combination therapy for HIV' in Section 4 of this leaflet.
Danish: Læs oplysningerne under 'Andre bivirkninger ved kombinationsbehandling af hiv' i punkt 4 i denne indlægsseddel.
English: For example, if your dose is 30 ml, you need to take 3 syringe-fulls of medicine Take the syringe out of the bottle and wash it thoroughly in clean water.
Danish: Hvis din samlede dosis f.eks. er 30 ml, skal du tage 3 sprøjter fyldt med medicin.
English: Slowly push the plunger in, allowing time to swallow.
Danish: Tryk langsomt stemplet i bund, så du får tid til at synke medicinen.
English: What Ziagen is and what it is used for Ziagen is used to treat HIV (human immunodeficiency virus) infection.
Danish: Virkning og anvendelse Ziagen anvendes til behandling af hiv-infektioner (humant immundefektvirus).
English: Percent with <400 copies/ml vRNA
Danish: Procent med < 400 pr. ml vRNA
English: It is recommended that HIV infected women do not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Danish: For at undgå overførsel af hiv anbefales det, at hiv-inficerede kvinder under ingen omstændigheder ammer deres børn.
English: Pull out the syringe plunger until the syringe contains the first part of your full dose Turn the bottle the right way up.
Danish: Træk i sprøjtens stempel, indtil sprøjten indeholder den første mængde af din samlede dosis.
English: These were primarily asymptomatic HIV infected patients - Centre for Disease Control and Prevention (CDC) stage A. They were randomised to receive either abacavir 600 mg once daily or 300 mg twice daily, in combination with efavirenz and lamivudine given once daily.
Danish: Disse var primært asymptomatiske hiv-inficerede patienter - Centre for Disease Control and Prevention (CDC) stadie A. De blev randomiseret til at modtage enten abacavir 600 mg én gang daglig eller 300 mg 2 gange daglig, i kombination med efavirenz og lamivudin givet én gang daglig.
English: Even patients who don't have the HLA-B*5701 gene may still develop a hypersensitivity reaction (a serious allergic reaction).
Danish: Selv patienter, som ikke har genet HLA-B*5701, kan udvikle en overfølsomhedsreaktion (en alvorlig allergisk reaktion).
English: The demonstration of the benefit of Ziagen is mainly based on results of studies performed in adult treatment-naïve patients using a regimen of Ziagen 300 mg twice daily in combination with zidovudine and lamivudine.
Danish: Fordelen ved Ziagen er hovedsageligt baseret på resultater af studier med voksne behandlingsnaive patienter med et regime af Ziagen 300 mg 2 gange daglig i kombination med zidovudin og lamivudin.
English: If you are hypersensitive to Ziagen, return all your unused Ziagen tablets for safe disposal.
Danish: Hvis du er overfølsom over for Ziagen, skal du returnere alle dine Ziagen-tabletter, så de kan blive destrueret korrekt.
English: Package leaflet: Information for the user Ziagen 20 mg/ml oral solution
Danish: Indlægsseddel: Information til brugeren Ziagen 20 mg/ml oral opløsning
English: In a study of 20 HIV-infected patients receiving abacavir 300 mg twice daily, with only one 300 mg dose taken prior to the 24 hour sampling period, the geometric mean terminal carbovir-TP intracellular half-life at steady-state was 20.6 hours, compared to the geometric mean abacavir plasma half-life in this study of 2.6 hours.
Danish: I et studie af 20 hiv-inficerede patienter der fik abacavir 300 mg 2 gange daglig, med kun én 300 mg dosis indtaget før prøveudtagning efter 24 timer, var den geometriske gennemsnitlige terminale carbovir-TP intracellulære halveringstid ved steady state 20,6 timer, sammenlignet med den geometriske gennemsnitlige abacavir plasmahalveringstid i dette studie på 2,6 timer.
English: The other ingredients are sorbitol 70% (E420), saccharin sodium, sodium citrate, citric acid anhydrous, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), propylene glycol (E1520), maltodextrin, lactic acid, glyceryl triacetate, artificial strawberry and banana flavour, purified water, sodium hydroxide and/or hydrochloric acid for pH adjustment.
Danish: Øvrige indholdsstoffer: Sorbitol 70 % (E420), saccharinnatrium, natriumcitrat, vandfri citronsyre, methylparahydroxybenzoat (E218), propylparahydroxybenzoat (E216), propylenglycol (E1520), maltodextrin, mælkesyre, glyceryltriacetat, syntetisk jordbær- og banansmag, renset vand, natriumhydroxid og/eller saltsyre til pH-justering.
English: Contains amongst others: sorbitol (340 mg/ml, E420), methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216).
Danish: Indeholder blandt andet: sorbitol (340 mg/ml, E420), methylparahydroxybenzoat (E218) og propylparahydroxybenzoat (E216).
English: An oral solution (20 mg abacavir/ml) is also available for the treatment of children over three months of age and weighing less than 14 kg, or for people who need a lower than usual dose, or who cannot take tablets.
Danish: Ziagen findes også som oral opløsning (20 mg abacavir/ml) til børn over tre måneder med en kropsvægt under 14 kg, eller til patienter, der har behov for en lavere dosis, eller som ikke kan synke tabletter.
English: Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported to occur in the setting of immune reactivation; however, the reported time to onset is more variable and these events can occur many months after initiation of treatment (see section 4.4).
Danish: Autoimmune sygdomme (som f.eks. Graves´ sygdom og autoimmun hepatitis) er også blevet rapporteret i forbindelse med immunreaktivering; dog er den rapporterede tid til frembrud mere variabel, og frembrud kan forekomme mange måneder efter behandlingsstart (se pkt.
English: Iron oxide yellow
Danish: Gult jernoxid.
English: If you are hypersensitive to Ziagen, return all your unused Ziagen oral solution for safe disposal.
Danish: Hvis du er overfølsom over for Ziagen, skal du returnere al din Ziagen oral opløsning, så det kan blive destrueret korrekt.
English: Plasma HIV-1 RNA <80 c/ml Risk difference (once daily-twice daily)
Danish: Plasma HIV-1-RNA <80 kopier/ml Risikodifference (én gang daglig vs. to gange daglig)
English: Glaxo Operations UK Ltd (trading as GlaxoWellcome Operations) Harmire Road
Danish: Glaxo Operations UK Ltd. (registreret som GlaxoWellcome Operations) Harmire Road
English: In adults treated with abacavir in combination with lamivudine and zidovudine the proportion of patients with undetectable viral load (<400 copies/ml) was approximately 70% (intention to treat analysis at 48 weeks) with corresponding rise in CD4 cells.
Danish: Hos voksne, behandlet med abacavir i kombination med lamivudin og zidovudin, var andelen af patienter med en udetekterbar virusbyrde (< 400 kopier/ml) ca. 70 % (”intention to treat”-analyse efter 48 uger) med et tilsvarende øget CD4-celletal.
English: The adapter is placed in the neck of the bottle and the syringe attached to this.
Danish: Adapteren sættes i flaskehalsen og sprøjten sættes fast i adaptoren.
English: ViiV Healthcare BV, Huis ter Heideweg 62, 3705 LZ Zeist, Netherlands
Danish: ViiV Healthcare BV, Huis ter Heideweg 62, 3705 LZ Zeist, Holland
English: It is important to take Ziagen regularly, because if you take it at irregular intervals, you may be more likely to have a hypersensitivity reaction.
Danish: Det er vigtigt, at du tager Ziagen regelmæssigt, da der er større risiko for at få en overfølsomhedsreaktion, hvis du tager medicinen uregelmæssigt.
English: Manufacturer: Glaxo Operations UK Ltd, (trading as GlaxoWellcome Operations) Harmire Road Barnard Castle Co. Durham DL12 8DT United Kingdom or ViiV Healthcare Trading Services UK Limited, 12 Riverwalk,
Danish: Glaxo Operations UK Ltd. (registreret som GlaxoWellcome Operations), Harmire Road, Barnard Castle, Co. Durham DL12 8DT, Storbritannien eller ViiV Healthcare Trading Services UK Limited, 12 Riverwalk, Citywest Business Campus, Dublin 24, Irland
English: Ziagen also contains preservatives (parahydroxybenzoates) which may cause allergic reactions (possibly delayed).
Danish: Ziagen indeholder også konserveringsmidler (parahydroxybenzoater), der kan udløse en overfølsomhedsreaktion (eventuelt forsinket).
English: Hypersensitivity reactions (see also section 4.8)
Danish: Overfølsomhedsreaktioner (se også pkt.
English: Once daily (600 mg) administration:
Danish: Administration én gang daglig (600 mg):
English: The antiviral activity of abacavir in cell culture was not antagonized when combined with the nucleoside reverse transcriptase inhibitors (NRTIs) didanosine, emtricitabine, lamivudine, stavudine, tenofovir or zidovudine, the non-nucleoside reverse transcriptase inhibitor (NNRTI) nevirapine, or the protease inhibitor (PI) amprenavir.
Danish: I cellekulturer blev abacavirs antivirale aktivitet ikke antagoniseret ved kombination med nukleosid revers transkriptasehæmmerne (NRTI'er) didanosin, emtricitabin, lamivudin, stavudin, tenofovir eller zidovudin, non-nukleosid revers transkriptasehæmmeren (NNRTI) nevirapin eller proteasehæmmeren (PI) amprenavir.
English: In pre-clinical toxicology studies, abacavir treatment was shown to increase liver weights in rats and monkeys.
Danish: I prækliniske toksikologiske studier blev det påvist, at behandling med abacavir øgede levervægten hos rotter og aber.
English: Methylhydroxypropylcellulose Titanium dioxide Polysorbate 80
Danish: Metylhydroxypropylcellulose Titandioxid
English: If you have stopped taking Ziagen
Danish: Hvis du holder op med at tage Ziagen
English: In a meta-analysis of five clinical trials where abacavir was added to intensify therapy, of 166 subjects, 123 (74%) had M184V/I, 50 (30%) had T215Y/F, 45 (27%) had M41L, 30 (18%) had K70R and 25 (15%) had D67N.
Danish: 123 (74 %) ud af de 166 forsøgspersoner havde M184V/I, 50 (30 %) havde T215Y/F, 45 (27 %) havde M4IL, 30 (18 %) havde K70R og 25 (15 %) havde D67N.
English: According to clinical trials performed in children abacavir is rapidly and well absorbed from oral solution and tablet formulations administered to children.
Danish: Ifølge kliniske studier med børn absorberes abacavir hurtigt og godt, når det gives som oral opløsning og tabletter.
English: Film-coated Tablets
Danish: Filmovertrukne tabletter
English: No dosage adjustment of Ziagen is necessary in patients with renal dysfunction.
Danish: Dosisjustering af Ziagen er ikke nødvendig hos patienter med nyreinsufficiens.
English: As well as the side effects listed below for Ziagen, other conditions can develop during combination therapy for HIV.
Danish: Ud over bivirkninger ved Ziagen nævnt nedenfor, kan du få andre sygdomme, når du får kombinationsbehandling mod hiv.
English: Similarly, greater proportions of children treated with the abacavir containing combinations had HIV-1 RNA ≤50 copies/ml at 48 weeks (53%, 42% and 28% respectively, p=0.07).
Danish: Ligeledes havde en større andel af børn behandlet med kombinationer, som indeholdte abacavir, HIV-1-RNA ≤ 50 kopier/ml ved 48 uger (henholdsvis 53 %, 42 % og 28 %, p=0,07).
English: 1206 HIV-infected paediatric patients aged 3 months to 17 years were enrolled in the ARROW Trial (COL105677), 669 of whom received abacavir and lamivudine either once or twice daily (see section 5.1).
Danish: 1.206 HIV-inficerede patienter i alderen 3 måneder til 17 år blev inkluderet i ARROW-studiet (COL105677); heraf fik 669 patienter abacavir og lamivudin enten som én daglig dosis eller som 2 daglige doser (se pkt.
English: Malignant tumours occurred in the preputial gland of males and the clitoral gland of females of both species, and in rats in the thyroid gland of males and the liver, urinary bladder, lymph nodes and the subcutis of females.
Danish: Ondartede tumorer opstod i forhudskirtlen hos hannerne og i clitoriskirtlen hos hunnerne hos begge arter og i leveren, urinblæren, lymfekirtler og i underhuden hos hunrotter.
English: After a median follow-up of 144 weeks, 25% of subjects on the ZDV/3TC/ABC/EFV arm and 26% on the ZDV/3TC/EFV arm were categorised as having virological failure.
Danish: Ved en middelvurdering efter 144 uger blev 25 % af patienterne i behandling med ZDV/3TC/ABC/EFV og 26 % af patienterne i behandling med ZDV/3TC/EFV kategoriseret, som havende virologisk svigt.
English: Very rare: erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis
Danish: Almindelig: Udslæt (uden systemiske reaktioner) Meget sjælden: Erythema multiforme, Stevens-Johnsons syndrom og toksisk epidermal nekrolyse
English: Adults, adolescents and children weighing at least 25 kg
Danish: Voksne, unge og børn, der vejer mindst 25 kg:
English: Anyone taking Ziagen could develop a hypersensitivity reaction to abacavir, which could be life threatening if they continue to take Ziagen.
Danish: Alle, der tager Ziagen, kan få en overfølsomhedsreaktion over for abacavir, der kan være livstruende, hvis de fortsætter med at tage Ziagen.
English: However, abacavir HSRs have been reported at a lower frequency in patients who do not carry this allele.
Danish: Derimod er frekvensen af en overfølsomhedsreaktion over for abacavir rapporteret med lavere frekvens hos patienter der ikke er bærer af dette allel.
English: Therefore no dosage reduction is required in patients with renal impairment.
Danish: Derfor er dosisjustering ikke nødvendig hos patienter med nedsat nyrefunktion.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON - TABLETS
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE YDRE KARTON - TABLETTER
English: Isolates from most patients experiencing virological failure with a regimen containing abacavir in pivotal clinical trials showed either no NRTI-related changes from baseline (45%) or only M184V or M184I selection (45%).
Danish: In vivo-resistens (behandlingsnaive patienter): Isolater fra patienter, som har haft virologisk svigt under en behandling med abacavir i pivotale kliniske studier, viste i de fleste tilfælde enten ingen NRTI-relaterede ændringer i forhold til baseline (45 %) eller kun M184V- eller M1841-mutationer (45 %).
English: Take special care with Ziagen
Danish: Vær ekstra forsigtig med at tage Ziagen
English: • if you are allergic (hypersensitive) to abacavir (or any other medicine containing abacavir - such as Triumeq, Trizivir or Kivexa) or any of the other ingredients of this medicine (listed in Section 6)
Danish: • hvis du er allergisk (overfølsom) over for abacavir (eller anden medicin, der indeholder abacavir, f.eks. Triumeq, Trizivir eller Kivexa) eller et af de øvrige indholdsstoffer i dette lægemiddel (angivet i punkt 6).
English: Median Change vRNA (log10 c/ml)
Danish: Uge 4 (n = 166) n Median ændring vRNA (log10 c/ml)
English: Intracellular pharmacokinetics
Danish: Intracellulære farmakokinetikker
English: The recommended dose is 8 mg/kg twice a day or 16 mg/kg once a day, up to a maximum total daily dose of 600 mg daily.
Danish: Den sædvanlige dosis er 8 mg/kg 2 gange daglig eller 16 mg/kg én gang daglig, dog maksimalt en total dosis på 600 mg daglig.
English: GlaxoSmithKline Pharmaceuticals S.A., ul., Grunwaldzka 189, 60-322 Poznan, Poland.
Danish: Grunwaldzka 189, 60-322 Poznan, Polen.
English: Any two NRTIassociated mutations Any three NRTIassociated mutations Four or more NRTIassociated mutations
Danish: Fire eller flere NRTIforbundne mutationer
English: In a separate study comparing the unblinded NRTI combinations (with or without blinded nelfinavir) in children, a greater proportion treated with abacavir and lamivudine (71%) or abacavir and zidovudine (60%) had HIV-1 RNA ≤400 copies/ml at 48 weeks, compared with those treated with lamivudine and zidovudine (47%)[ p=0.09, intention to treat analysis].
Danish: I et selvstændigt studie, som sammenlignede de ikke-blindede NRTI kombinationer (med og uden blindet nelfinavir) hos børn, havde en større andel af patienter behandlet med abacavir og lamivudin (71 %) eller abacavir og zidovudin (60 %) HIV-1-RNA ≤ 400 kopier/ml efter 48 uger, sammenlignet med de patienter, som blev behandlet med lamivudin og zidovudin (47 %) [p=0,09, ”intention-to-treat” analyse].
English: Ziagen is also available as an oral solution for use in children over three months of age and weighing less than 14 kg and for those patients for whom the tablets are inappropriate.
Danish: Den orale opløsning anvendes til børn, der er over 3 måneder og som vejer under 14 kg, og til patienter hvor tabletformuleringen er uhensigtsmæssig.
English: 1206 paediatric patients aged 3 months to 17 years enrolled in the ARROW Trial (COL105677) and were dosed according to the weight - band dosing recommendations in the World Health Organisation treatment guidelines (Antiretroviral therapy of HIV infection in infants and children, 2006).
Danish: 1.206 pædiatriske patienter i alderen 3 måneder til 17 år blev inkluderet i ARROW-studiet (COL105677) og blev doseret i henhold til vægtgruppe-anbefalingerne i WHO's behandlingsvejledning (Antiretroviral therapy of HIV infection in infants and children, 2006).
English: The Ziagen pack includes an Alert Card, to remind you and medical staff about abacavir hypersensitivity.
Danish: Der er vedlagt et oplysningskort i pakningen med Ziagen for at gøre dig og sundhedspersonalet opmærksom på overfølsomhed over for abacavir.
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING BOTTLE LABEL - ORAL SOLUTION
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN INDRE EMBALLAGE FLASKEETIKET - ORAL OPLØSNING
English: Microcrystalline cellulose Sodium starch glycollate Magnesium stearate Colloidal anhydrous silica
Danish: Mikrokrystallinsk cellulose Natriumstivelsesglycolat Magnesiumstearat Kolloid vandfri silica.
English: Gastrointestinal disorders Common: nausea, vomiting, diarrhoea Rare: pancreatitis
Danish: Almindelig: Kvalme, opkastning, diarré Sjælden: Pancreatitis
English: The pharmacokinetics of abacavir have been studied in patients with mild hepatic impairment (Child-Pugh score 5-6) receiving a single 600 mg dose ; the median (range) AUC value was 24.1 (10.4 to 54.8) ug.h/ml.
Danish: Abacavirs farmakokinetik er blevet undersøgt hos patienter med let nedsat leverfunktion (Child-Pugh score 5-6), der fik en enkelt dosis på 600 mg; den mediane (interval) AUC var 24,1 (10,4 - 54,8) mikrog∙time/ml.
English: (COL105677) and were dosed according to the weight - band dosing recommendations in the World Health Organisation treatment guidelines (Antiretroviral therapy of HIV infection in infants and children, 2006).
Danish: måneder til 17 år blev inkluderet i ARROW-studiet (COL105677) og blev doseret i henhold til vægtgruppe-anbefalingerne i WHO's behandlingsvejledning (Antiretroviral therapy of HIV infection in infants and children, 2006).
English: Do not store above 30°C
Danish: Må ikke opbevares ved temperaturer over 30 °C
English: In a crossover study in 27 HIV-infected patients, intracellular carbovir-TP exposures were higher for the abacavir 600 mg once daily regimen (AUC24,ss + 32 %, Cmax24,ss + 99 % and Ctrough + 18 %) compared to the 300 mg twice daily regimen.
Danish: I et ”crossoverstudie” med 27 hiv-inficerede patienter fandt man en højere intracellulær eksponering af carbovir-TP ved behandling med 600 mg abacavir én gang daglig (AUC24,ss + 32 %, Cmax24,ss + 99 % og Ctrough + 18 %) sammenlignet med behandling med 300 mg 2 gange daglig.
English: In the as treated (AT) analysis the difference between both treatment arms was more noticeable (88% of patients in the abacavir group, compared to 95% of patients in the zidovudine group (point estimate for treatment difference: -6.8, 95% CI11.8; -1.7).
Danish: I ”as treated” (AT) analysen var forskellen mellem begge behandlingsarme mere påfaldende (88 % af patienterne i abacavirgruppen, sammenlignet med 95 % af patienterne i zidovudingruppen (punktestimat for behandlingsforskel: -6,8, 95 % CI -11,8; -1,7).
English: K65R was absent and L74V and Y115F were uncommon (≤3%).
Danish: K65R blev ikke fundet, og L74V og Y115F forekom sjældent