FrancophonIA/ELRC3.0 huggingface dataset:
English: If patients taking felodipine suffer from headache, nausea, dizziness or fatigue and ability to react may be impaired.
Croatian: Ako bolesnici koji uzimaju felodipin imaju glavobolju, mučninu, omaglicu ili osjećaju umor, može biti ugrožena njihova sposobnost reagiranja.
English: The systemic availability of felodipine is approximately 15% and is independent of dose in the therapeutic dose range.
Croatian: Bioraspoloživost felodipina je oko 15% i unutar raspona terapijskih doza ne ovisi o dozi.
English: 10 mg tablet
Croatian: 10 mg tableta
English: if you have chest pain of recent onset, or angina pectoris that is lasting for more than 15 minutes or longer or is more severe than usual.
Croatian: - ako ste nedavno osjetili bol u prsima ili ako imate anginu pektoris koja traje dulje od 15 minuta ili je izraženija nego obično. - ako imate bolest srčanih zalistaka ili srčanog mišića, a niste se savjetovali s liječnikom.
English: Felodipine Cmax and AUC increased 8-fold and 6-fold, respectively, when felodipine was coadministered with the strong CYP3A4 inhibitor itraconazole.
Croatian: Cmax felodipina se povećao 8 puta, a AUC 6 puta kada je felodipin primijenjen istovremeno s itrakonazolom, snažnim inhibitorom izoenzima CYP3A4.
English: In a reproduction study in monkeys, an abnormal position of the distal phalange(s) was noticed.
Croatian: U reproduktivnom ispitivanju na majmunima, uočen je abnormalan položaj distalne falange/falangi.
English: if you suffer from uncompensated heart failure.
Croatian: - ako bolujete od zatajenja srca koje se ne liječi.
English: The renal vascular resistance is decreased by felodipine.
Croatian: Renalna vaskularna otpornost smanjuje se pri terapiji felodipinom.
English: When felodipine was coadministered with carbamazepine, phenytoin or phenobarbital, the Cmax and AUC of felodipine were decreased by 82% and 96% respectively.
Croatian: Istovremena primjena felodipina i karbamazepina, fenitoina ili fenobarbitala uzrokovala je smanjenje vrijednosti Cmax za 82%, a AUC-a za 96%.
English: In non-clinical reproductive toxicity studies there were foetal developmental effects, which are considered to be due to the pharmacological action of felodipine.
Croatian: U nekliničkim ispitivanjima reproduktivne toksičnosti uočene su promjene fetalnog razvoja, za koje se smatra da su povezane sa farmakološkim djelovanjem felodipina.
English: Felodipine improves exercise tolerance and reduces anginal attacks in patients with stable effort-induced angina pectoris.
Croatian: Felodipin poboljšava toleranciju na napor i smanjuje broj napada angine u bolesnika sa stabilnom,
English: Felodipine does not influence urinary albumin excretion.
Croatian: Felodipin ne utječe na izlučivanje albumina mokraćom.
English: The primary haemodynamic effect of felodipine is a reduction of total peripheral vascular resistance, which leads to a decrease in blood pressure.
Croatian: Primarni hemodinamički učinak felodipina je smanjenje ukupnog perifernog vaskularnog otpora koje dovodi do snižavanja krvnog tlaka.
English: Plendil contains lactose and castor oil
Croatian: Plendil sadrži laktozu i ricinusovo ulje
English: Very common ≥ 1/10
Croatian: Vrlo često ≥ 1/10
English: In a single dose (felodipine prolonged-release 5 mg) pharmacokinetic study with a limited number of children aged between 6 and 16 years (n=12) there was no apparent relationship between the age and AUC, Cmax or half-life of felodipine.
Croatian: U farmakokinetičkom ispitivanju jednokratne doze (felodipin s produljenim oslobađanjem 5 mg) s ograničenim brojem djece u dobi od 6 do 16 godina (n=12) nije uočena očita povezanost između dobi i
English: Examples are:
Croatian: Primjerice:
English: Do not take Plendil if you are pregnant.
Croatian: Ako ste trudni, nemojte uzimati Plendil.
English: Mild enlargement of the gums has been reported in patients with an inflammation in the mouth (gingivitis/periodontitis).
Croatian: Blago oticanje desni zabilježeno je u bolesnika s upalom usne šupljine (gingivitis/periodontitis).
English: The enlargement can be avoided or reversed by careful oral hygiene.
Croatian: Oticanje se može izbjeći ili ukloniti pažljivom dentalnom higijenom.
English: Reproduction studies in rabbits have shown a dose-related reversible enlargement of the mammary glands of the parent animals and dose-related digital anomalies in the foetuse.
Croatian: Ispitivanja reproduktivnosti u kunića pokazala su reverzibilno povećanje mliječnih žlijezda u životinja roditelja povezano s dozom i anomalije prstiju ploda povezane s dozom.
English: Plendil and associated names (see Annex I) 2.5 mg prolonged-release tablets Plendil and associated names (see Annex I) 5 mg prolonged-release tablets Plendil and associated names (see Annex I) 10 mg prolonged-release tablets
Croatian: Plendil i pridružena imena (vidjeti Dodatak I) 2,5 mg tablete s produljenim oslobađanjem Plendil i pridružena imena (vidjeti Dodatak I) 5 mg tablete s produljenim oslobađanjem Plendil i pridružena imena (vidjeti Dodatak I) 10 mg tablete s produljenim oslobađanjem
English: Felodipine is extensively metabolised in the liver by cytochrome P450 3A4 (CYP3A4) and all identified metabolites are inactive.
Croatian: Felodipin se opsežno metabolizira u jetri pomoću citokroma P50 3A4 (CYP3A4), a svi identificirani metaboliti su neaktivni.
English: Elderly people Your doctor may initiate treatment with the lowest available dose.
Croatian: Liječnik će liječenje započeti najnižom mogućom dozom.
English: • Erythromycin
Croatian: • eritromicin
English: Plendil can have minor or moderate influence on your ability to drive and use machines.
Croatian: Upravljanje vozilima i strojevima Plendil može imati slab ili umjeren utjecaj na sposobnost upravljanja vozilima i strojevima.
English: • Ketoconazole
Croatian: • ketokonazol
English: Felodipine does not affect daily potassium excretion.
Croatian: Felodipin ne utječe na dnevno izlučivanje kalija.
English: Felodipine can cause flushing, headache, palpitations, dizziness and fatigue.
Croatian: Felodipin može prouzročiti crvenilo praćeno osjećajem užarenosti, glavobolju, palpitacije, omaglicu i umor.
English: Felodipine is metabolised in the liver by cytochrome P450 3A4 (CYP3A4).
Croatian: Felodipin se metabolizira u jetri pomoću citokroma P450 3A4 (CYP3A4).
English: • Nevirapine
Croatian: • nevirapin
English: In cyclosporin-treated renal transplant recipients, felodipine reduces blood pressure and improves both the renal blood flow and the glomerular filtration rate.
Croatian: U primatelja bubrežnog transplantata liječenih ciklosporinom felodipin snižava krvni tlak i poboljšava renalni protok krvi i brzinu glomerularne filtracije.
English: Mild gingival enlargement has been reported in patients with pronounced gingivitis/periodontitis.
Croatian: Blaga hiperplazija gingive prijavljena je u bolesnika s izraženim gingivitisom/periodontitisom.
English: • medicines to treat HIV protease inhibitors (such as ritonavir)
Croatian: • lijekovi protiv HIV-a/inhibitori proteaza (npr. ritonavir)
English: There is limited clinical trial experience of the use of felodipine in hypertensive paediatric patients.
Croatian: Kliničko iskustvo s primjenom felodipina u hipertenzijskih pedijatrijskih bolesnika je ograničeno.
English: The following undesirable effects have been identified.
Croatian: Ustanovljene su sljedeće nuspojave.
English: Hypersensitivity reactions, e.g. angio-oedema, fever
Croatian: Reakcije preosjetljivosti, npr. angioedem, vrućica
English: 1 blister of 14 tablets
Croatian: 1 blister s 14 tableta
English: Coronary vascular resistance is decreased and coronary blood flow and myocardial oxygen supply are increased by felodipine due to dilatation of both epicardial arteries and arterioles.
Croatian: Pod utjecajem felodipina koronarni vaskularni otpor se smanjuje, a protok krvi i opskrba miokarda kisikom se povećavaju zahvaljujući dilataciji epikardijalnih arterija i arteriola.
English: High-density polyethylene bottle with a cap of polypropylene PVC/PVDC blister and Aluminum blister
Croatian: PVC/PVDC blister i aluminijski blister
English: In case of lack of efficacy due to decreased felodipine exposure when combined with potent inducers of CYP3A4, adjustment of felodipine dose and/or discontinuation of the CYP3A4 inducer should be considered.
Croatian: U slučaju nedostatne djelotvornosti uslijed smanjenog izlaganja felodipinu kada ga se kombinira sa snažnim induktorima izoenzima CYP3A4, treba razmotriti prilagodbu doze felodipina i/ili ukidanje induktora izoenzima CYP3A4.
English: Uncommon Tachycardia, palpitations
Croatian: Manje često Tahikardija, palpitacije
English: Carton (pack) contents
Croatian: Sadržaj pakiranja (kutije)
English: • rifampicin (medicine to treat infections)
Croatian: • rifampicin (lijek za liječenje infekcija)
English: 3 blisters of 10 tablets 1 bottle of 30 tablets
Croatian: 3 blistera s po 10 tableta 1 boca od 30 tableta
English: When felodipine and erythromycin were coadministered, the Cmax and AUC of felodipine were increased by about 2.5-fold.
Croatian: Istovremena primjena felodipina i eritromicina dovela je do povećanja Cmax i AUC-a felodipina od približno 2,5 puta.
English: Each tablet contains 2.5 mg 5 mg or 10 mg of felodipine.
Croatian: Jedna tableta sadrži 2,5 mg 5 mg ili 10 mg felodipina.
English: Very common: may affect more than 1 in 10 people
Croatian: Vrlo česte nuspojave: javljaju se u više od 1 na 10 osoba
English: The reduction in systemic blood pressure caused by felodipine leads to decreased left ventricular afterload and myocardial oxygen demand.
Croatian: Sniženje sistemskog krvnog tlaka uzrokovano felodipinom za posljedicu ima smanjeno tlačno opterećenje lijevog ventrikula i smanjenu potrebu miokarda za kisikom.
English: • Itraconazole
Croatian: • itrakonazol
English: Felodipine is a vascular selective calcium antagonist, which lowers arterial blood pressure by decreasing systemic vascular resistance.
Croatian: Mehanizam djelovanja Felodipin je vazoselektivni antagonist kalcija koji snižava arterijski tlak smanjivanjem sistemskog vaskularnog otpora.
English: [To be completed nationally] [See Annex I - To be completed nationally]
Croatian: [Ispunjava država članica] [Vidjeti Dodatak I - ispunjava država članica]
English: In case of clinically significant adverse events due to elevated felodipine exposure when combined with strong CYP3A4 inhibitors, adjustment of felodipine dose and/or discontinuation of the CYP3A4 inhibitor should be considered.
Croatian: U slučaju klinički značajnih nuspojava uslijed povećanog izlaganja felodipinu kada ga se kombinira sa snažnim inhibitorima izoenzima CYP3A4, treba razmotriti prilagodbu doze felodipina i/ili ukidanje inhibitora izoenzima CYP3A4.
English: How to store Plendil [To be completed nationally]
Croatian: Kako čuvati Plendil [Ispunjava država članica]
English: Felodipine possesses a mild natriuretic/diuretic effect and fluid retention does not occur.
Croatian: Felodipin ima blago natriuretsko/diuretsko djelovanje te stoga ne dolazi do zadržavanja tekućine.
English: • erythromycin (medicine to treat infections)
Croatian: • eritromicin (lijek za liječenje infekcija)
English: Tell your doctor if you are breast-feeding or about to start breast-feeding.
Croatian: Obavijestite svog liječnika ako dojite ili namjeravate početi dojiti.
English: • Carbamazepine
Croatian: • karbamazepin
English: Very rare < 1/10,000
Croatian: Rijetko ≥ 1/10 000 i < 1/1000 Vrlo rijetko < 1/10 000
English: The combination with strong CYP3A4 inhibitors should be avoided.
Croatian: Kombinaciju felodipina sa snažnim inhibitorima izoenzima CYP3A4 treba izbjegavati.
English: Each tablet contains 10 mg felodipine.
Croatian: Jedna tableta sadrži 10 mg felodipina.
English: Treatment can be started with 5 mg once daily.
Croatian: Liječenje se može započeti dozom od 5 mg jednom dnevno.
English: The combination with strong CYP3A4 inducers should be avoided.
Croatian: Kombinaciju felodipina sa snažnim induktorima izoenzima CYP3A4 treba izbjegavati.
English: • carbamazepine (medicine to treat epilepsy)
Croatian: • karbamazepin (lijek za liječenje epilepsije)
English: See leaflet for further information.
Croatian: Više informacija potražite u Uputi o lijeku.
English: Each tablet contains 5 mg felodipine.
Croatian: Jedna tableta sadrži 5 mg felodipina.
English: • Haemodynamically significant cardiac valvular obstruction
Croatian: • hemodinamički značajna opstrukcija srčanih zalistaka • dinamička opstrukcija izlaznog trakta srca
English: Enzyme interactions
Croatian: Interakcije na razini enzima
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 2.5 mg (or 5 mg, or 10 mg) felodipine
Croatian: Jedna tableta sadrži 2,5 mg (ili 5 mg, ili 10 mg) felodipina
English: Pack sizes of 14, 20, 28, 30, 90, 98 and 100 tablets
Croatian: Pakiranja od 14, 20, 28, 30, 90, 98 i 100 tableta
English: If you stop taking Plendil
Croatian: Prije nego prestanete uzimati Plendil,
English: Headache Dizziness, paraesthesia
Croatian: Glavobolja Omaglica, parestezija
English: Treatment should be initiated with 5 mg once daily and, if needed, increased to 10 mg once daily.
Croatian: Liječenje treba započeti dozom od 5 mg jednom dnevno te je po potrebi povećati na 10 mg jednom dnevno.
English: Concomitant administration of substances which interfere with CYP3A4 enzyme system may affect plasma concentrations of felodipine.
Croatian: Istovremena primjena tvari koje ometaju sustav enzima CYP3A4 mogu utjecati na plazmatske koncentracije felodipina.
English: Interactions leading to increased plasma concentration of felodipine CYP3A4 enzyme inhibitors have been shown to cause an increase in felodipine plasma concentrations.
Croatian: Interakcije koje uzrokuju povećanje plazmatskih koncentracija felodipina Dokazano je da inhibitori izoenzima CYP3A4 uzrokuju povećanje plazmatskih koncentracija felodipina.
English: • Muscular pain
Croatian: • bol u mišićima
English: • Pain in joints
Croatian: • bol u zglobovima
English: Therefore such combinations should be avoided.
Croatian: Stoga takve kombinacije treba izbjegavati (vidjeti dio 4.5).
English: Pack sizes of 20, 28, 30, 98 and 100 tablets
Croatian: Pakiranja od 20, 28, 30, 98 i 100 tableta
English: The study showed benefits of lowering SBP and DBP down to 139 and 83 mmHg, respectively.
Croatian: Ispitivanje je pokazalo da je došlo do smanjenja sistoličkog krvnog tlaka na 139 mmHg i dijastoličkog krvnog tlaka na 83 mmHg.
English: Treatment should be started with 5 mg once a day.
Croatian: Liječenje treba započeti dozom od 5 mg jednom dnevno.
English: Plendil and associated names (see Annex I) 2.5 mg [5 mg or, 10 mg] prolonged-release tablets [See Annex I - To be completed nationally] felodipine
Croatian: Uputa o lijeku: Informacija za bolesnika Plendil i pridružena imena (vidjeti Dodatak I) 2,5 mg [5 mg ili 10 mg] tablete s produljenim oslobađanjem [Vidjeti Dodatak I - ispunjava država članica]
English: Very common Uncommon Very rare
Croatian: Vrlo često Manje često
English: • medicines to treat HIV infection (such as efavirenz, nevirapine)
Croatian: • inhibitori proteaza HIV-a (poput ritonavira) • lijekovi za liječenje infekcija HIV-om (poput efavirenza, nevirapina)
English: 3 blisters of 30 tablets
Croatian: 3 blistera s po 30 tableta
English: 4 blisters of 7 tablets
Croatian: 4 blistera s po 7 tableta
English: Carnauba wax Iron oxide yellow (E172) Hypromellose 6 mPa·s Macrogol 6000
Croatian: Ovojnica karnauba vosak željezov oksid, žuti (E 172) hipromeloza 6 mPa s makrogol 6000 titanijev dioksid (E 171)
English: Taking Plendil may cause your gums to become swollen.
Croatian: Plendil može uzrokovati oticanje desni.
English: If you experience headache, nausea, dizziness or fatigue your ability to react may be impaired.
Croatian: Ako imate glavobolju, mučninu, omaglicu ili osjećaj umora, može biti ugrožena
English: Felodipine has minor or moderate influence on the ability to drive and use machines.
Croatian: 4.7 Utjecaj na sposobnost upravljanja vozilima i rada sa strojevima Felodipin ima slab ili umjeren utjecaj na sposobnost upravljanja vozilima i rada sa strojevima.
English: If this is not sufficient, plasma volume should be increased by infusion of e.g., glucose, saline, or dextran.
Croatian: Ako to nije dovoljno, treba povećati volumen plazme infuzijom,
English: Plendil 2.5 mg prolonged-release tablet is yellow, circular, biconvex, engraved A/FL on one side and 2.5 on the other side, with a diameter of 8.5 mm.
Croatian: Plendil 2,5 mg tableta s produljenim oslobađanjem je žuta, okrugla, bikonveksna tableta promjera 8,5 mm s utisnutom oznakom A/FL s jedne te oznakom 2,5 s druge strane.
English: Iron oxide reddish-brown (E172) Iron oxide yellow (E172) Hypromellose 6 mPa·s Macrogol 6000
Croatian: željezov oksid, žuti (E 172) hipromeloza 6 mPa s makrogol 6000 titanijev dioksid (E 171)
English: • Phenytoin
Croatian: • fenitoin
English: 14 tablets 20 tablets 28 tablets 30 tablets 90 tablets 98 tablets 100 tablets
Croatian: 14 tableta 20 tableta 28 tableta 30 tableta 90 tableta 98 tableta 100 tableta
English: 20 tablets 28 tablets 30 tablets 98 tablets 100 tablets
Croatian: 20 tableta 28 tableta 30 tableta 98 tableta 100 tableta
English: This may lead to myocardial ischaemia in susceptible patients.
Croatian: Felodipin može uzrokovati značajnu hipotenziju s naknadnom tahikardijomštoo u osjetljivih bolesnika može dovesti do ishemije miokarda.
English: Concomitant administration of drugs that strongly induce or inhibit CYP3 A4 enzymes result in extensively decreased or increased plasma levels of felodipine, respectively.
Croatian: Istodobna primjena lijekova koji su snažni induktori ili inhibitori izoenzima CYP3A4 uzrokuje izrazito smanjenje odnosno povećanje razine felodipina u plazmi.
English: 2 blisters of 10 tablets
Croatian: 2 blistera s po 10 tableta
English: 14 tablets 20 tablets 28 tablets 30 tablets 98 tablets 100 tablets
Croatian: 14 tableta 20 tableta 28 tableta 30 tableta 98 tableta 100 tableta
English: Peripheral oedema Fatigue
Croatian: Periferni edem Umor
English: • phenytoin (medicine to treat epilepsy)
Croatian: • fenitoin (lijek za liječenje epilepsije)
English: Iron oxide reddish-brown (E172) (Only used for Plendil 5 mg and 10 mg) Iron oxide yellow (E172)
Croatian: Ovojnica: karnauba vosak željezov oksid, crvenkastosmeđi (E172) (upotrebljava se samo za Plendil 5 mg i 10 mg) željezov oksid, žuti (E 172) hipromeloza 6 mPa.s makrogol 6000 titanijev dioksid (E 171)
English: 7 blisters of 14 tablets
Croatian: 7 blistera s po 14 tableta
English: Please consult your doctor and seek advice before you stop taking Plendil.
Croatian: obratite se svom liječniku i zatražite njegov savjet.
English: Each tablet contains 28 mg lactose and 2.5 mg polyoxyl 40 hydrogenated castor oil.
Croatian: Jedna tableta sadrži 28 mg laktoze i 2,5 mg polioksil 40 hidrogeniranog ricinusovog ulja.
English: 10 blisters of 10 tablets
Croatian: 10 blistera s po 10 tableta
English: [Plendil 5 mg and 10 mg] Carnauba wax
Croatian: [Plendil 5 mg i 10 mg] karnauba vosak željezov oksid, crvenkastosmeđi (E 172)
English: The tablet is yellow, circular, biconvex, engraved A/FL on one side and 2.5 on the other side, with a diameter of 8.5 mm.
Croatian: Tableta je žuta, okrugla, bikonveksna, promjera 8,5 mm s utisnutom oznakom A/FL s jedne i 2,5 s druge strane.
English: Plendil 10 mg prolonged-release tablet is reddish-brown, circular, biconvex, engraved A/FE on one side and 10 on the other side, with a diameter of 9.
Croatian: Plendil 10 mg tableta s produljenim oslobađanjem je crvenkastosmeđa, okrugla, bikonveksna tableta promjera 9 mm s utisnutom oznakom A/FE s jedne i oznakom 10 s druge strane.
English: Increased liver enzymes
Croatian: Vrlo rijetko Povišene vrijednosti jetrenih enzima
English: • Acute myocardial infarction
Croatian: • akutni infarkt miokarda • nestabilna angina pektoris
English: You should tell your doctor as soon as possible if you become pregnant while using this medicine.
Croatian: Ako tijekom uzimanja ovog lijeka zatrudnite, što prije obavijestite svog liječnika.
English: Rare: may affect up to 1 in 1,000 people
Croatian: Rijetke nuspojave: javljaju se u manje od 1 na 1000 osoba • nesvjestica
English: Enzyme inhibiting and enzyme inducing substances of cytochrome P450 isoenzyme 3A4 may exert an influence on the plasma level of felodipine.
Croatian: Tvari koje inhibiraju ili induciraju izoenzim 3A4 citokroma P450 mogu utjecati na razine felodipina u plazmi.
English: • cimetidine (medicine to treat gastric ulcers)
Croatian: • cimetidin (lijek za liječenje čira na želucu)
English: • Hypericum perforatum (Saint John's wort)
Croatian: • gospina trava (Hypericum perforatum)
English: The tablets can be administered without food or following a light meal not rich in fat or carbohydrate.
Croatian: Tablete se mogu uzeti bez hrane ili nakon laganog obroka,
English: Each tablet contains 28 mg lactose and 10 mg polyoxyl 40 hydrogenated castor oil.
Croatian: Jedna tableta sadrži 28 mg laktoze i 10 mg polioksil 40 hidrogeniranog ricinusovog ulja.
English: Cardiac effects
Croatian: Hemodinamički učinci
English: Common: may affect up to 1 in 10 people
Croatian: Česte nuspojave: javljaju se u manje od 1 na 10 osoba
English: Each tablet contains 28 mg lactose and 5 mg polyoxyl 40 hydrogenated castor oil.
Croatian: Jedna tableta sadrži 28 mg laktoze i 5 mg polioksil 40 hidrogeniranog ricinusovog ulja.
English: The tablet is pink, circular, biconvex, engraved A/Fm on one side and 5 on the other side, with a diameter of 9 mm.
Croatian: Tableta je ružičasta, okrugla, bikonveksna, promjera 9 mm s utisnutom oznakom A/Fm s jedne i 5 s druge strane.
English: LIST OF EXCIPIENTS Contains lactose and polyoxyl 40 hydrogenated castor oil.
Croatian: Lijek sadrži laktozu i polioksil 40 hidrogenirano ricinusovo ulje.
English: felodipine
Croatian: Nuspojava
English: Photosensitivity reactions, leucocytoclastic vasculitis
Croatian: leukocitoklastični vaskulitis
English: Renal impairment Dose adjustment is not needed in patients with impaired renal function.
Croatian: U bolesnika s oštećenjem bubrega nije potrebna prilagodba doze.
English: Breastfeeding
Croatian: felodipin
English: 1 bottle of 100 tablets 10 blisters of 10 tablets
Croatian: 1 bočica od 100 tableta
English: Oral use
Croatian: UPUTE ZA UPORABU
English: INSTRUCTIONS ON USE [To be completed nationally]
Croatian: NAČIN IZDAVANJA LIJEKA [Ispunjava država članica]
English: Dose-dependent ankle swelling can occur in patients treated with felodipine.
Croatian: U bolesnika liječenih felodipinom može doći do oticanja gležnjeva koje je povezano s dozom.
English: Interactions leading to decreased plasma concentration of felodipine Enzyme inducers of the cytochrome P450 3A4 system have been shown to cause a decrease in plasma concentrations of felodipine.
Croatian: Dokazano je da enzimski induktori citokroma P450 3A4 snižavaju plazmatske koncentracije felodipina.
English: Plendil contains the active substance felodipine.
Croatian: Što je Plendil i za što se koristi Plendil sadrži djelatnu tvar felodipin.
English: The tablet is reddish-brown, circular, biconvex, engraved A/FE on one side and 10 on the other side, with a diameter of 9 mm.
Croatian: Tableta je crvenkastosmeđa, okrugla, bikonveksna, promjera 9 mm s utisnutom oznakom A/FE s jedne i 10 s druge strane.
English: Other undesirable effects may occur.
Croatian: Mogu se javiti i druge nuspojave.
English: Common Uncommon Rare
Croatian: Vrlo rijetko Polakizurija
English: • Pregnancy
Croatian: • trudnoća
English: 1 bottle of 30 tablets 3 blisters of 10 tablets
Croatian: 1 bočica od 30 tableta
English: Uncommon Rare
Croatian: Rijetko Vrlo rijetko
English: • itraconazole (medicine to treat fungi)
Croatian: • itrakonazol (lijek za liječenje gljivičnih infekcija) • ketokonazol (lijek za liječenje gljivičnih infekcija)
English: PACKAGE LEAFLET
Croatian: Veličina pakiranja
English: Symptoms
Croatian: Liječenje
English: Very rare: may affect up to 1 in 10,000 people
Croatian: • impotencija/seksualna disfunkcija Vrlo rijetke nuspojave: javljaju se u manje od 1 na 10 000 osoba
English: Pollakisuria
Croatian: OBLIK
English: - The active substance felodipine.
Croatian: Interakcije koje uzrokuju snižavanje plazmatskih koncentracija felodipina