FrancophonIA/ELRC3.0 huggingface dataset:
English: - Monitoring of blood glucose in patients on concomitant insulin therapy, especially those on high doses, or insulin secretagogues and combination treatment is warranted.
Estonian: - Samaaegset insuliinravi, eriti suurtes annustes, või insuliini sekretagooge ja kombinatsioonravi saavatel patsientidel on vaja jälgida veresuhkru taset.
English: Each vial contains 11.3 mg of metreleptin After reconstitution, each mL contains 5 mg of metreleptin (5 mg/mL)
Estonian: Üks viaal sisaldab 11,3 mg metreleptiini Pärast lahustamist sisaldab 1 ml 5 mg metreleptiini (5 mg/ml)
English: Type I glass vial (3 mL) with a chlorobutyl rubber stopper and an aluminium seal/red plastic flip-off cap.
Estonian: I tüüpi klaasist viaal (3 ml) klorobutüülkummist punnkorgi ja alumiiniumsulguriga / punase eemaldatava plastkorgiga.
English: Signs and/or symptoms consistent with pancreatitis should prompt an appropriate clinical evaluation.
Estonian: Pankreatiidile viitavate tunnuste ja/või sümptomite korral tuleb patsienti kohe sobival viisil kliiniliselt hinnata.
English: • Do not remove the rubber seal.
Estonian: • Ärge eemaldage kummitihendit.
English: Line up the top rim of the plunger with the line for the prescribed dose.
Estonian: Viige kolvi ülemine serv määratud annuse joonega kohakuti.
English: Weight (kg) x 0.06 mg/kg = Individual patient daily starting dose in mg Weight (kg) x 0.012 mL/kg = Individual patient daily starting volume to inject in mL
Estonian: Kaal (kg) x 0,012 mg/kg = konkreetse patsiendi ööpäevase algannuse maht ml-tes
English: o Hypoglycaemia with concomitant use of insulin and other antidiabetics may occur.
Estonian: o Samaaegsel kasutamisel insuliini ja muude diabeediravimitega võib tekkida hüpoglükeemia.
English: • being clumsy and dropping things
Estonian: • kohmakus ja asjade mahapillamine
English: Vascular disorders
Estonian: Vaskulaarsed häired süvaveenitromboos
English: • Remove the needle cover.
Estonian: • Eemaldage nõelakate.
English: After dissolving the vial contents in 0.6 millilitres of water for injections, each millilitre contains 5 milligrams of metreleptin.
Estonian: Pärast viaali sisu lahustamist 0,6 milliliitri süsteveega sisaldab iga milliliiter 5 milligrammi metreleptiini.
English: • Do not attach the needle to the syringe.
Estonian: • Ärge ühendage nõela süstla külge.
English: Serious and/or severe infections that were temporally associated with > 80% blocking activity against metreleptin occurred in 5 generalised LD patients.
Estonian: Viiel generaliseerunud lipodüstroofiaga patsiendil tekkis tõsiseid ja/või raskeid infektsioone, mis olid rohkem kui 80%-l juhtudel ajalises seoses blokeeriva aktiivsusega metreleptiini suhtes.
English: 25 kg patient is initiated at 0.06 mg/kg of Myalepta.
Estonian: 25 kg patsiendi Myalepta algannus on 0,06 mg/kg.
English: Fat tissue increased, Injection site haemorrhage, Injection site pain, Injection site pruritus, Injection site swelling, Malaise, Peripheral swelling
Estonian: Üldised häired ja manustamiskoha reaktsioonid väsimus, verevalum süstekohal, punetus süstekohal, reaktsioon süstekohal rasvkoe suurenemine, veritsemine süstekohal, valu süstekohal, sügelus süstekohal, turse süstekohal, halb enesetunne, perifeerne turse
English: • feeling more sleepy
Estonian: • suurem unisus
English: It is a white powder supplied in a glass vial with a rubber stopper and an aluminium seal with a white plastic flip-off cap.
Estonian: See on valge pulber, mis on saadaval klaasviaalis, millel on kummist punnkork ja alumiiniumsulgur valge eemaldatava plastkorgiga.
English: • Do not move the plunger.
Estonian: • Ärge kolbi liigutage.
English: Each vial contains 3 mg of metreleptin After reconstitution, each mL contains 5 mg of metreleptin (5 mg/mL)
Estonian: Üks viaal sisaldab 3 mg metreleptiini Pärast lahustamist sisaldab 1 ml 5 mg metreleptiini (5 mg/ml)
English: With the needle still in the vial, turn the vial and syringe upside down.
Estonian: Hoides nõela viaalis, keerake viaal ja süstal tagurpidi.
English: • stomach pain, feeling sick (nausea) and being sick (vomiting)
Estonian: • kõhuvalu, iiveldus ja oksendamine
English: Attach the needle to the 1 mL syringe.
Estonian: Kinnitage nõel 1 ml süstla külge.
English: • Insert the 3 mL syringe needle into the vial, through the rubber seal.
Estonian: • Sisestage 3 ml süstla nõel läbi kummitihendi viaali.
English: 0.156 mL 0.15 mL
Estonian: 0,156 ml
English: This will include for example instructions for handling possible ADRs o Allergic reactions can occur with Myalepta use.
Estonian: o Myalepta kasutamisel võib tekkida allergilisi reaktsioone.
English: No formal pharmacokinetic studies were conducted in patients with renal impairment.
Estonian: Neerufunktsiooni kahjustusega patsientidega ei ole vormikohaseid uuringuid läbi viidud.
English: It is a white powder supplied in a glass vial with a rubber stopper and an aluminium seal with a blue plastic flip-off cap.
Estonian: See on valge pulber, mis on saadaval klaasviaalis, millel on kummist punnkork ja alumiiniumsulgur sinise eemaldatava plastkorgiga.
English: Table 1 Metreleptin recommended dose Baseline weight
Estonian: Tabel 1 Metreleptiini soovitatav annus Ravieelne kaal
English: • a plastic ampoule
Estonian: Süstevee plastampull
English: − A starting dose is 5 mg (1 mL of solution).
Estonian: − Algannus on 5 mg (1 ml lahust).
English: It is a white powder supplied in a glass vial with a rubber stopper and an aluminium seal with a red plastic flip-off cap.
Estonian: See on valge pulber, mis on saadaval klaasviaalis, millel on kummist punnkork ja alumiiniumsulgur punase eemaldatava plastkorgiga.
English: The glass ampoule is a sealed container.
Estonian: Klaasampull on õhukindlalt suletud mahuti.
English: 12) Insert the needle of the 3 mL syringe containing the 2.2 mL of water for injection all the way into the Myalepta vial containing the powder.
Estonian: 12) Sisestage 2,2 ml süstevett sisaldava 3 ml süstla nõel lõpuni Myalepta pulbriviaali.
English: • thigh
Estonian: • pearinglus
English: • Each 0.1 mL is shown as a number with a big line.
Estonian: • Iga 0,1 ml on tähistatud numbri ja pika joonega.
English: Both males and females > 40 kg
Estonian: Mehed ja naised > 40 kg
English: 5) Withdraw 1.1 mL of water for injection into the 3 mL syringe.
Estonian: 5) Tõmmake 3 ml süstlasse 1,1 ml süstevett.
English: Example: A male patient is initiated at 2.5 mg of Myalepta daily.
Estonian: Meespatsiendi Myalepta algannus on 2,5 mg ööpäevas.
English: 25 kg patient is initiated at 0.012 mL/kg = 0.3 mL of Myalepta solution to inject
Estonian: 25 kg patsiendi Myalepta süstelahuse algannus on 0,012 ml/kg = 0,3 ml
English: After reconstitution with 1.1 mL water for injections (see section 6.6), each mL contains 5 mg of metreleptin.
Estonian: Pärast lahustamist 1,1 ml süstevees (vt lõik 6.6) sisaldab 1 ml 5 mg metreleptiini.
English: For males > 40 kg once daily dose
Estonian: Meestel > 40 kg annus üks kord ööpäevas
English: Metreleptin works by copying the effects of leptin.
Estonian: Metreleptiin matkib oma toimega leptiini toimeid.
English: • Each 1 U is shown as a smaller line between the big lines.
Estonian: • Iga 1 Ü on tähistatud lühikese joonega pikkade joonte vahel.
English: Pull the plunger down carefully • Pull it down until the top rim of the plunger lines up with the black 0.6 mL line.
Estonian: Tõmmake kolbi ettevaatlikult alla • Tõmmake seda alla, kuni kolvi ülemine serv on musta 0,6 ml joonega kohakuti.
English: 12) Insert the needle of the 3 mL syringe containing the 1.1 mL of water for injection all the way into the Myalepta vial containing the powder.
Estonian: 12) Sisestage 1,1 ml süstevett sisaldava 3 ml süstla nõel lõpuni Myalepta pulbriviaali.
English: • Pull up until the top rim of the plunger lines up with the black 1.1 mL line.
Estonian: • Tõmmake üles, kuni kolvi ülemine serv on musta 1,1 ml joonega kohakuti.
English: o Neutralising antibodies may develop on Myalepta therapy.
Estonian: o Ravi ajal Myaleptaga võivad tekkida neutraliseerivad antikehad.
English: Pull the plunger down carefully • Pull it down until the top rim of the plunger lines up with the black 1.1 mL line.
Estonian: Tõmmake kolbi ettevaatlikult alla • Tõmmake seda alla, kuni kolvi ülemine serv on musta 1,1 ml joonega kohakuti.
English: • Insert the 1 mL syringe needle into the vial, through the rubber seal.
Estonian: • Sisestage 1 ml süstla nõel läbi kummitihendi viaali.
English: Remaining reconstituted product should be discarded after use.
Estonian: Kasutamata jäänud lahustatud lahus tuleb pärast kasutamist hävitada.
English: Pull the plunger down carefully • Pull it down until the top rim of the plunger lines up with the black 2.2 mL line.
Estonian: Tõmmake kolbi ettevaatlikult alla • Tõmmake seda alla, kuni kolvi ülemine serv on musta 2,2 ml joonega kohakuti.
English: Step D: Filling the syringe with Myalepta for injection
Estonian: Samm D. Süstla täitmine Myaleptaga süstimiseks
English: 5) Withdraw 2.2 mL of water for injection into the 3 mL syringe.
Estonian: 5) Tõmmake 3 ml süstlasse 2,2 ml süstevett.
English: Myalepta is used to treat the complications of not having enough leptin in patients with lipodystrophy.
Estonian: Myaleptat kasutatakse leptiini vaegusest põhjustatud tüsistuste raviks lipodüstroofiaga patsientidel.
English: Table 3 Required syringe for Myalepta reconstitution with water for injection Syringe
Estonian: Tabel 3 Myalepta lahustamiseks süsteveega vajalik süstal Süstal
English: o The risk of medication error: - Responsibility of the prescribing physician to provide appropriate training to the patient/carer who will administer the treatment and that the first dose should be administered in the presence of a doctor or nurse - The requirement to perform regular follow-ups with the patient/carer to ensure continued correct and compliant Myalepta reconstitution and treatment - Guidance on the appropriate syringe size ancillary administration set to prescribe according to the dosage of Myalepta and how to read the syringe volumes - How to access a video on line which shows step by step how to reconstitute, measure the correct dose and administer it subcutaneously o The association between LD and lymphoma and that the patient will be monitored during treatment.
Estonian: - Juhised sobivas suuruses süstlaga manustamiskomplekti kohta olenevalt Myalepta annusest ning süstla mahu lugemiseks - Kuidas leida veebist video, milles tutvustatakse samm-sammult õige annuse lahustamist, mõõtmist ja naha alla manustamist.
English: • Pull up until the top rim of the plunger lines up with the black 0.6 mL line.
Estonian: • Tõmmake üles, kuni kolvi ülemine serv on musta 0,6 ml joonega kohakuti.
English: The benefits and risks of treatment should be carefully considered in patients with acquired generalised LD and/or in patients with significant haematological abnormalities (including leukopenia, neutropenia, bone marrow abnormalities, lymphoma, and/or lymphadenopathy).
Estonian: Omandatud generaliseerunud lipodüstroofiaga ja/või oluliste hematoloogiliste häiretega (sh leukopeenia, neutropeenia, luuüdi häired, lümfoom ja/või lümfadenopaatia) patsientidel tuleb hoolikalt kaaluda ravi kasu-riski suhet.
English: A separate case of anaplastic large cell lymphoma was reported in a paediatric patient receiving the medicinal product who did not have haematological abnormalities before treatment.
Estonian: Ühel seda ravimit kasutanud lapspatsiendil, kellel ei olnud enne ravi alustamist hematoloogilisi häireid, esines eraldi anaplastilise suurerakulise lümfoomi juhtum.
English: 0.168 mL 0.16 mL
Estonian: 0,168 ml
English: 12) Insert the needle of the 1 mL syringe containing the 0.6 mL of water for injection all the way into the Myalepta vial containing the powder.
Estonian: 12) Sisestage 0,6 ml süstevett sisaldava 1 ml süstla nõel lõpuni Myalepta pulbriviaali.
English: - Lymphoproliferative disorders, including lymphoma have been reported in patients with acquired generalised LD not treated with Myalepta.
Estonian: - Omandatud generaliseerunud lipodüstroofia korral, mida ei ole Myaleptaga ravitud, on esinenud lümfoproliferatiivseid häireid, sealhulgas lümfoomi.
English: 0.204 mL 0.20 mL
Estonian: 0,204 ml
English: After reconstitution with 2.2 mL water for injections (see section 6.6), each mL contains 5 mg of metreleptin.
Estonian: Pärast lahustamist 2,2 ml süstevees (vt lõik 6.6) sisaldab 1 ml 5 mg metreleptiini.
English: - The benefits and risks of Myalepta should be carefully considered in patients with acquired LD and/or those with significant haematologic abnormalities (including leukopenia, neutropenia, bone marrow abnormalities, lymphoma and/or lymphadenopathy).
Estonian: - Omandatud lipodüstroofiaga ja/või oluliste hematoloogiliste kõrvalekalletega (sh leukopeenia, neutropeenia, luuüdi kõrvalekalded, lümfoom ja/või lümfadenopaatia) patsientidel tuleb hoolikalt kaaluda Myalepta kasutamise kasu ja riski suhet.
English: Myalepta 5.8 mg powder for injection metreleptin
Estonian: Myalepta 5,8 mg süstelahuse pulber Metreleptiin
English: Talk to your doctor if you are breast-feeding.
Estonian: Teatage arstile, kui te imetate last.
English: o Loss of efficacy, potentially due to neutralising antibodies, may occur in patients on Myalepta therapy.
Estonian: o Myalepta-ravi saavatel patsientidel võib ravimi efektiivsus potentsiaalselt väheneda neutraliseerivate antikehade tõttu.
English: • Pull up until the top rim of the plunger lines up with the black 2.2 mL line.
Estonian: • Tõmmake üles, kuni kolvi ülemine serv on musta 2,2 ml joonega kohakuti.
English: 0.144 mL 0.14 mL
Estonian: 0,144 ml
English: • diarrhoea
Estonian: • reiepiirkond
English: The reconstituted solution should be injected into the abdomen, thigh or upper arm tissue.
Estonian: Lahustatud lahus tuleb süstida kõhu, reie või õlavarre piirkonna koesse.
English: 0.252 mL 0.25 mL
Estonian: 0,252 ml
English: − A starting dose is 2.5 mg (0.5 mL of solution).
Estonian: − Algannus on 2,5 mg (0,5 ml lahust).
English: • The needle should go all the way into the vial.
Estonian: • Nõel tuleb sisestada lõpuni viaali.
English: Myalepta 11.3 mg powder for injection metreleptin
Estonian: Myalepta 11,3 mg süstelahuse pulber Metreleptiin
English: Do not reconstitute with other diluents.
Estonian: Mitte kasutada lahjendamiseks muid lahjendeid.
English: Attach the needle to the 3 mL syringe.
Estonian: Kinnitage nõel 3 ml süstla külge.
English: 5) Withdraw 0.6 mL of water for injection into the 1 mL syringe.
Estonian: 5) Tõmmake 1 ml süstlasse 0,6 ml süstevett.
English: Rotation of injection sites is recommended in patients co-administering insulin (or other subcutaneous medicinal products) and Myalepta.
Estonian: - Insuliini (või muude subkutaansete ravimite) manustamisel koos Myaleptaga on soovitatav patsientidel süstekohti vahetada.
English: 0.132 mL 0.13 mL
Estonian: 0,132 ml
English: Do not inject into a muscle.
Estonian: Ärge süstige lihasesse.
English: Example: A 15 kg patient is initiated at 0.06 mg/kg of Myalepta.
Estonian: 15 kg patsiendi Myalepta algannus on 0,06 mg/kg.
English: 0.288 mL 0.28 mL
Estonian: 0,288 ml
English: Myalepta 11.3 mg powder for solution for injection Using a 3 mL syringe with a 21-gauge or smaller diameter needle, withdraw 2.2 mL of water for injection.
Estonian: Kasutades 3 ml süstalt 21 G või väiksema diameetriga nõelaga, tõmmata välja 2,2 ml süstevett.
English: Step B: Filling the 3 mL syringe with 2.2 mL of water for injections
Estonian: Samm B. 3 ml süstla täitmine 2,2 ml süsteveega.
English: Treatment should be initiated and monitored by a healthcare professional experienced in the diagnosis and management of metabolic disorders.
Estonian: Ravi võib alustada ainult ainevahetushäiretega patsientide diagnoosimises ja ravis kogenud tervishoiuspetsialist ning see peab toimuma tema järelevalve all.
English: Myalepta 5.8 mg powder for solution for injection Using a 3 mL syringe with a 21-gauge or smaller diameter needle, withdraw 1.1 mL of water for injection.
Estonian: Kasutades 3 ml süstalt 21 G või väiksema diameetriga nõelaga, tõmmata välja 1,1 ml süstevett.
English: • You will be given the 1 mL syringe to use if your daily dose is more than 1.5 mg up to 5 mg,
Estonian: • Teile antakse 1 ml süstal, kui teie ööpäevane annus on rohkem kui 1,5 mg ja kuni 5 mg, mis vastab mahult 0,3 ml kuni 1,0 ml Myalepta lahusele.
English: Instructions for reconstitution
Estonian: Toime reaktsioonikiirusele
English: Myalepta 3 mg powder for injection metreleptin
Estonian: Myalepta 3 mg süstelahuse pulber
English: Step B: Filling the 3 mL syringe with 1.1 mL of water for injections
Estonian: Samm B. 3 ml süstla täitmine 1,1 ml süsteveega.
English: 2.2 millilitres of water for injections, each millilitre contains 5 milligrams of metreleptin.
Estonian: Pärast viaali sisu lahustamist 2,2 milliliitri süsteveega sisaldab iga milliliiter 5 milligrammi metreleptiini.
English: Myalepta 3 mg powder for solution for injection Using a 1 mL syringe with a 21-gauge or smaller diameter needle, withdraw 0.6 mL of water for injection.
Estonian: Kasutades 1 ml süstalt 21 G või väiksema diameetriga nõelaga, tõmmata välja 0,6 ml süstevett.
English: Read the “Instructions for Use” (see section 7) for how to make the solution before injecting.
Estonian: Lahuse valmistamise kohta enne süstimist lugege lõiku „Kasutamisjuhised“ (vt lõik 7).
English: 1.1 millilitres of water for injections, each millilitre contains 5 milligrams of metreleptin.
Estonian: Pärast viaali sisu lahustamist 1,1 milliliitri süsteveega sisaldab iga milliliiter 5 milligrammi metreleptiini.
English: 6.6 Special precautions for disposal and other handling
Estonian: Erihoiatused ravimpreparaadi hävitamiseks ja käsitlemiseks
English: 0.276 mL 0.27 mL
Estonian: 0,276 ml
English: After reconstitution with 0.6 mL water for injections (see section 6.6), each mL contains 5 mg of metreleptin.
Estonian: Pärast lahustamist 0,6 ml süstevees (vt lõik 6.6) sisaldab 1 ml 5 mg metreleptiini.
English: 0.180 mL 0.18 mL
Estonian: 0,180 ml
English: Glutamic acid
Estonian: Glutamiinhape
English: 0.192 mL 0.19 mL
Estonian: 0,192 ml
English: 0.108 mL 0.10 mL
Estonian: 0,108 ml
English: • who have generalised lipodystrophy (the whole of your body does not have enough fatty tissue) It is used, when other treatments have been ineffective, in adults, and adolescents 12 years or over:
Estonian: • kellel on generaliseerunud lipodüstroofia (kogu kehas ei ole piisavalt rasvkude).
English: Package leaflet: Information for the patient Myalepta 11.3 mg powder for solution for injection metreleptin This medicine is subject to additional monitoring.
Estonian: Pakendi infoleht: teave patsiendile Myalepta 11,3 mg süstelahuse pulber
English: • pain below the ribs like heartburn or indigestion
Estonian: • kõrvetiste või seedehäire taoline valu roiete all
English: See the
Estonian: II LISA
English: 0.264 mL 0.26 mL
Estonian: 0,264 ml
English: Always use a new ampoule or vial of water for injection.
Estonian: • klaasviaalis (kummist punnkorgiga) Kasutage alati uut ampulli või viaali või süstevett.
English: 15) Mix the powder and water for injection
Estonian: 15) Segage pulber süsteveega
English: Myalepta 11.3 mg powder for solution for injection Type I glass vial (5 mL) with a bromobutyl rubber stopper and an aluminium seal/white plastic flip-off cap.
Estonian: I tüüpi klaasist viaal (5 ml) bromobutüülkummist punnkorgi ja alumiiniumsulguriga / valge eemaldatava plastkorgiga.
English: There was evidence of improvement in renal and hepatic function in patients with generalised LD treated with metreleptin.
Estonian: Generaliseerunud lipodüstroofiaga patsientidel, keda raviti metreleptiiniga, paranes neeru- ja maksafunktsioon.
English: Package leaflet: Information for the patient Myalepta 5.8 mg powder for solution for injection metreleptin This medicine is subject to additional monitoring.
Estonian: Pakendi infoleht: teave patsiendile Myalepta 5,8 mg süstelahuse pulber
English: 0.240 mL 0.24 mL
Estonian: 0,240 ml
English: • All of the water for injection should be injected into the vial.
Estonian: • Viaali tuleb süstida kogu süstevesi.
English: - Large dose reductions of 50% or more of baseline insulin requirements may be needed in the first 2 weeks of Myalepta treatment.
Estonian: o Samaaegsel kasutamisel insuliini ja muude diabeediravimitega võib tekkida hüpoglükeemia: - Myalepta ravi kahe esimese nädala jooksul võib algtaseme insuliinivajadus tunduvalt väheneda - 50% või rohkem.
English: • increase in fatty tissue
Estonian: • rasvkoe suurenemine
English: • Do not remove the needle guard.
Estonian: • Ärge eemaldage nõelakaitset.
English: • You must check for air pockets or air bubbles in your 1 mL syringe.
Estonian: • 1 ml süstla korral tuleb kontrollida õhutaskute või õhumullide olemasolu.
English: Package leaflet: Information for the patient Myalepta 3 mg powder for solution for injection metreleptin This medicine is subject to additional monitoring.
Estonian: Pakendi infoleht: teave patsiendile Myalepta 3 mg süstelahuse pulber
English: Dose of Myalepta
Estonian: Myalepta annus
English: • sudden severe pain in your stomach (abdomen)
Estonian: • äkki tekkiv tugev kõhuvalu
English: 0.216 mL 0.21 mL
Estonian: 0,216 ml
English: Musculoskeletal and connective tissue disorders
Estonian: Lihas-skeleti ja sidekoe kahjustused artralgia, müalgia
English: Partial LD subgroup
Estonian: Osalise lipodüstroofiaga alarühm
English: Insert the 1 mL syringe into the glass ampoule.
Estonian: Sisestage klaasampulli 1 ml süstal.
English: Insert the 3 mL syringe into the glass ampoule.
Estonian: Sisestage klaasampulli 3 ml süstal.
English: Respiratory, thoracic and mediastinal disorders
Estonian: Respiratoorsed, rindkere ja mediastiinumi häired köha, hingeldus, pleuraefusioon
English: • Remove the needle guard.
Estonian: • Eemaldage nõelakaitse.
English: • fainting or feeling dizzy
Estonian: • minestamine ja pearinglus
English: Step B: Filling the 1 mL syringe with 0.6 mL of water for injections
Estonian: Samm B. 1 ml süstla täitmine 0,6 ml süsteveega.
English: Myalepta 5.8 mg powder for solution for injection
Estonian: Myalepta 5,8 mg süstelahuse pulber
English: - Tapering the dose over a two-week period is recommended in conjunction with a low fat diet. - Patients should be monitored during tapering.
Estonian: - Koos vähese rasvasisaldusega dieediga on soovitatav annust kahe nädala jooksul järkjärgult vähendada.
English: Do not use the solution if discoloured or cloudy, or if particulate matter remains.
Estonian: Mitte kasutada lahust, kui see on värvi muutnud, hägune või sisaldab osakesi.
English: Males and females ≤ 40 kg 0.06 mg/kg (0.012 mL/kg)
Estonian: 0,06 mg/kg (0,012 ml/kg)
English: Myalepta 3 mg powder for solution for injection metreleptin
Estonian: Myalepta 3 mg süstelahuse pulber Metreleptiin
English: • You must check for air pockets or air bubbles in your 3 mL syringe.
Estonian: • 3 ml süstla korral tuleb kontrollida õhutaskute või õhumullide olemasolu.
English: Missed dose
Estonian: Lahuse ümardatud maht
English: Using the glass ampoule
Estonian: Klaasampulli kasutamine
English: Tachycardia
Estonian: • rindkerevalu
English: • diabetes
Estonian: • suhkurtõbi
English: Starting daily dose (injection volume)
Estonian: Ööpäevane algannus (süstemaht)
English: • going to the toilet to pass urine more often
Estonian: • sagedam urineerimine
English: 0.120 mL 0.12 mL
Estonian: 0,120 ml
English: What you need to know before you use Myalepta 3.
Estonian: 1. Mis ravim on Myalepta ja milleks seda kasutatakse 2. Mida on vaja teada enne Myalepta kasutamist 3.
English: Investigations
Estonian: Näidustused
English: • Keeping the bottom of the ampoule still, snap the tip off.
Estonian: • Ampulli põhja paigal hoides murdke selle ots ära.
English: After IV administration, metreleptin clearance was shown to be 79.6 mL/kg/h in healthy volunteers.
Estonian: manustamist 79,6 ml/kg/h.
English: • severe pain in your stomach (abdomen)
Estonian: • tugev kõhuvalu
English: To remove the water for injection, break open the ampoule.
Estonian: Et saada süstimiseks vedel ravim, tuleb see pulbri lahustamiseks segada Myalepta pulbriga.
English: • Do not use a double dose to make up for a forgotten dose.
Estonian: • Ärge süstige kahekordset annust, kui annus jäi eelmisel korral süstimata.