FrancophonIA/ELRC3.0 huggingface dataset:
English: In addition, indinavir with ritonavir should not be administered with alfuzosin, meperidine, piroxicam, propoxyphene, bepridil, encainide, flecanide, propafenone, quinidine, fusidic acid, clozapine, clorazepate, diazepam, estazolam and flurazepam.
Danish: Desuden bør indinavir kombineret med ritonavir ikke administreres sammen med alfuzosin, meperidin, piroxicam, propoxyfen, bepridil, encainid, flecanid, propafenon, quinidin, fusidinsyre, clozapin, clorazepat, diazepam, estazolam og flurazepam.
English: Combination of rifampicin with CRIXIVAN with or without concomitant low-dose ritonavir is contraindicated (see section 4.5).
Danish: Kombinationen af rifampicin og CRIXIVAN med eller uden samtidig administration af ritonavir i lav dosis er kontraindiceret (se pkt.
English: In addition, indinavir with ritonavir must not be administered with alfuzosin, meperidine, piroxicam, propoxyphene, bepridil, encainide, flecanide, propafenone, quinidine, fusidic acid, clozapine, clorazepate, diazepam, estazolam and flurazepam.
Danish: Desuden må indinavir sammen med ritonavir ikke administreres samtidigt med alfuzosin, mepiridin, piroxicam, propoxyphen, bepridil, encainid, flecainid, propafenon, quinidin, fusidinsyre, clozapin, clorazepat, diazepam, estazolam og flurazepam.
English: If you take more CRIXIVAN than you should, talk to your doctor as soon as possible.
Danish: Hvis De har taget for meget CRIXIVAN Tal med Deres læge snarest muligt, hvis De har taget mere CRIXIVAN, end De skulle.
English: CRIXIVAN 200 mg hard capsules are supplied in HDPE bottles with a polypropylene cap and a foil seal containing 180, 270 or 360 capsules.
Danish: CRIXIVAN 200 mg hårde kapsler leveres i HDPE-beholdere med polypropylenhætte og beskyttende folielukning, der indeholder 180, 270 eller 360 kapsler.
English: Indinavir levels may increase on stopping St. John's wort, and the dose of CRIXIVAN may need adjusting.
Danish: Indinavirkoncentrationen kan øges ved seponering af perikon, og det kan være nødvendigt at øge dosis for CRIXIVAN.
English: Indinavir AUC and Cmin:  (Relative to Indinavir 400 mg SD alone)
Danish: Indinavir AUC og Cmin:  (I forhold til indinavir 400 mg SD alene)
English: HDPE bottle with a polypropylene cap and a foil induction cap containing 180, 270 or 360 capsules.
Danish: HDPE-beholder med polypropylenlåg og folielukning, indeholdende 180, 270 eller 360 kapsler.
English: Saquinavir AUC:  360 % Saquinavir Cmin:  450 % (Relative to saquinavir 1,200 mg (soft gel formulation) alone)
Danish: Saquinavir AUC:  360 % Saquinavir Cmin:  450 % (I forhold til saquinavir 1200 mg (blød gelformulering) alene)
English: The combination of rifampicin and CRIXIVAN with concomitant low-dose ritonavir is contraindicated (see section 4.3).
Danish: Kombinationen af rifampicin og CRIXIVAN og samtidig administration af ritonavir i lav dosis er kontraindiceret (se pkt.
English: The capsules are semi-translucent white and coded ‘CRIXIVAN ™ 200 mg' in blue.
Danish: Kapslerne er delvis gennemsigtige, hvide og prægede CRIXIVAN™ 200 mg i blåt.
English: Indinavir and sulphamethoxazole/ trimethoprim can be coadministered without dose adjustment.
Danish: Indinavir og sulfamethoxazol/trimethoprim kan administreres samtidigt uden dosisjustering.
English: PDE5 INHIBITOR Sildenafil 25 mg SD (Indinavir 800 mg TID)
Danish: PDE5-HÆMMER Sildenafil 25 mg SD (Indinavir 800 mg TID)
English: Indinavir AUC and Cmin: ↔ (Relative to Indinavir 800 mg TID alone*)
Danish: Indinavir AUC and Cmin: ↔ (I forhold til indinavir 800 mg TID alene*)
English: Theophylline AUC and Cmin: ↔
Danish: Theophyllin AUC og Cmin: ↔
English: Careful monitoring of therapeutic and adverse effects is recommended when these medicines are concomitantly administered with indinavir.
Danish: Omhyggelig monitorering af terapeutiske virkninger og bivirkninger anbefales, når disse lægemidler administreres samtidigt med indinavir.
English: Zidovudine 200 mg TID (Indinavir 1,000 mg TID)
Danish: Zidovudin 200 mg TID (Indinavir 1000 mg TID)
English: Vardenafil dose should not exceed a maximum of 2.5 mg in a 72-hour period when given with a boosted protease inhibitor.
Danish: Vardenafildosis bør ikke overstige max. 2,5 mg over en 72-timers periode, når det gives sammen med en boostet proteasehæmmer.
English: Saquinavir AUC:  620 % Saquinavir Cmin:  450 % (Relative to saquinavir 800 mg SD (soft gel formulation) alone)
Danish: Saquinavir AUC:  620 % Saquinavir Cmin:  450 % (I forhold til saquinavir 800 mg SD (blød gelformulering) alene)
English: At steady state following a dose regimen of 800 mg/100 mg of indinavir/ritonavir every 12 hours with a low-fat meal, healthy volunteers in one study achieved geometric means: AUC0-12h 116,067 nM*h (90 % confidence interval = 101,680, 132,490), peak plasma concentrations 19,001 nM (90 % confidence interval = 17,538, 20,588), and plasma concentrations at 12 hours post dose 2,274 nM (90 % confidence interval = 1,701, 3,042).
Danish: Ved steady state efter et dosisregime på 800 mg/100 mg indinavir/ritonavirterapi hver 12. time i kombination med et fedtfattigt måltid, opnåedes i en undersøgelse følgende geometriske middelværdier: AUC0-12 timer på 116067 nM·t (90 % konfidensinterval = 101680, 132490), maksimale plasmakoncentrationer på 19001 nM (90 % konfidensinterval = 17538, 20588) og plasmakoncentrationer 12 timer efter dosering på 2274 nM (90 % konfidensinterval = 1701, 3042) hos raske frivillige.
English: • having a numb mouth
Danish: • følelsesløshed i munden
English: Careful monitoring of digoxin levels is recommended when digoxin is concomitantly administered with indinavir/ritonavir.
Danish: Omhyggelig monitorering af digoxinkoncentrationen anbefales, når digoxin administreres samtidigt med indinavir/ritonavir.
English: Each hard capsule contains indinavir sulphate corresponding to 200 mg of indinavir.
Danish: Hver hård kapsel indeholder indinavirsulfat svarende til 200 mg indinavir.
English: ANTIASTHMATIC Theophylline 250 mg SD (Indinavir 800 mg TID)
Danish: ASTMAMIDLER Theophyllin 250 mg SD (Indinavir 800 mg TID)
English: Indinavir AUC: ↓ 32 % Indinavir Cmin: ↓ 40 % (Relative to Indinavir 800 mg TID alone)
Danish: Indinavir AUC: ↓ 32 % Indinavir Cmin: ↓ 40 % (I forhold til indinavir 800 mg TID alene)
English: Didanosine enteric-coated 400 mg SD (Indinavir 800 mg SD)
Danish: Didanosin enterotablet 400 mg SD (Indinavir 800 mg SD)
English: Itraconazole 200 mg BID (Indinavir 600 mg TID)
Danish: Itraconazol 200 mg BID (Indinavir 600 mg TID)
English: ANALGESICS Methadone 20-60 mg QD (Indinavir 800 mg TID)
Danish: ANALGETIKA Methadon 20-60 mg QD (Indinavir 800 mg TID)
English: • altered taste sensations
Danish: • ændret smagsoplevelse
English: haematuria, proteinuria, crystalluria nephrolithiasis, dysuria.
Danish: Hæmaturi, proteinuri, krystalluri
English: Corresponding plasma concentrations at 8 hours post dose were 220 nM, 210 nM and 370 nM, respectively.
Danish: Tilsvarende plasmakoncentrationer 8 timer efter dosis var hhv. 220 nM, 210 nM og 370 nM. Relevansen af disse fund for ritonavir-boostet indinavir kendes ikke.
English: Indinavir AUC24hr:266 % Indinavir Cmin:24-fold; (Relative to Indinavir 800 mg TID alone*) Ritonavir AUC:  96 % Ritonavir Cmin:  371 %
Danish: Indinavir AUC24t:266 % Indinavir Cmin:24 gange; (I forhold til indinavir 800 mg TID alene*) Ritonavir AUC:  96 % Ritonavir Cmin:  371 %
English: Coadministration of CRIXIVAN with sildenafil is likely to result in an increase of sildenafil by competitive inhibition of metabolism.
Danish: Samtidig administration af CRIXIVAN og sildenafil medfører sandsynligvis stigning i sildenafil ved kompetitiv hæmning af metabolismen.
English: The capsules are semi-translucent white and coded ‘CRIXIVAN 400 mg' in green.
Danish: Kapslerne er delvis gennemsigtige, hvide og prægede CRIXIVAN™ 400 mg i grønt.
English: Each hard capsule contains indinavir sulphate corresponding to 400 mg of indinavir.
Danish: Hver hård kapsel indeholder indinavirsulfat svarende til 400 mg indinavir.
English: Sildenafil dose should not exceed a maximum of 25 mg in a 48-hour period in patients receiving concomitant indinavir therapy.
Danish: Sildenafil-dosis bør ikke overstige max. 25 mg i en 48timers periode hos patienter, der samtidig får indinavirbehandling.
English: CRIXIVAN 200 mg - packs of 180, 270 and 360 capsules - Outer carton
Danish: CRIXIVAN 200 mg - pakninger med 180, 270 og 360 kapsler - Ydre æske
English: When CRIXIVAN is used with ritonavir, consult the Summary of Product Characteristics of ritonavir for additional contraindications.
Danish: Se produktresumé for ritonavir vedrørende yderligere kontraindikationer, når CRIXIVAN anvendes sammen med ritonavir.
English: • kidney problems such as kidney infection, worsening or loss of kidney function
Danish: • nyreproblemer såsom nyreinfektion eller forværring eller svigt af nyrefunktion • smerter og besvær med at bevæge skulderen
English: Interaction with indinavir/ritonavir not studied Ritonavir induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Danish: Ritonavir inducerer oxidering ved CYP2C9 samt glucuronidering og som følge heraf forventes det at reducere plasmakoncentrationen af antikonvulsiva.
English: Coadministration of CRIXIVAN with vardenafil is likely to result in an increase of vardenafil by competitive inhibition of metabolism.
Danish: Samtidig administration af CRIXIVAN og vardenafil medfører sandsynligvis stigning i vardenafil ved kompetitiv hæmning af metabolismen.
English: Indinavir Cmin:  (Relative to Indinavir 1,000 mg TID alone)
Danish: Indinavir Cmin:  (I forhold til indinavir 1000 mg TID alene)
English: Indinavir Cmin: ↑ 118 % (Relative to Indinavir 800 mg TID alone)
Danish: Indinavir Cmin: ↑ 118 % (I forhold til indinavir 800 mg TID alene)
English: Coadministration of CRIXIVAN with tadalafil is likely to result in an increase of tadalafil by competitive inhibition of metabolism.
Danish: Samtidig administration af CRIXIVAN og tadalafil medfører sandsynligvis stigning i tadalafil ved kompetitiv hæmning af metabolismen.
English: There have been reports of increased bleeding, including spontaneous skin haematomas and haemarthroses, in haemophiliac patients type A and B treated with PIs.
Danish: Hos patienter med hæmofili A og B har der været flere rapporter om øget blødningstendens med spontane hudblødninger og ledblødninger under behandling med PIere.
English: Capsule shell: gelatin titanium dioxide (E 171) printing ink: indigo carmine (E 132).
Danish: Kapselskal: gelatine titandioxid (E171) prægeblæk: Titandioxid (E 171), indigocarmin (E 132).
English: CRIXIVAN 200 mg - packs of 180, 270 and 360 capsules - Bottle label
Danish: CRIXIVAN 200 mg - pakning med 180, 270 og 360 kapsler - Beholderetiket
English: HDPE bottles with a polypropylene cap and a foil induction cap containing 90 or 180 capsules.
Danish: HDPE-beholder med polypropylenlåg og folielukning indeholdende 90 eller 180 kapsler.
English: CRIXIVAN 400 mg - packs of 90 and 180 capsules - Bottle label
Danish: CRIXIVAN 400 mg - pakning med 90 og 180 kapsler - Beholderetiket
English: • stomach pain or swelling
Danish: • mavesmerter eller oppustethed
English: Stavudine 40 mg BID (Indinavir 800 mg TID)
Danish: Stavudin 40 mg BID (Indinavir 800 mg TID)
English: HERBAL MEDICATIONS St. John's wort (Hypericum perforatum) 300 mg TID (Indinavir 800 mg TID)
Danish: NATURLÆGEMIDLER Perikon (Hypericum perforatum) 300 mg TID (Indinavir 800 mg TID)
English: Desiccant should not be removed from the container.
Danish: Fjern ikke det fugtabsorberende middel fra beholderen.
English: Indinavir Cmin: ↑ 49 % (Relative to Indinavir 800 mg TID alone)
Danish: Indinavir Cmin: ↑ 49 % (I forhold til indinavir 800 mg TID alene)
English: Interaction with indinavir/ritonavir not studied Ritonavir may modify P-glycoprotein mediated fexofenadine efflux when coadministered resulting in increased concentrations of fexofenadine.
Danish: Ritonavir kan modificere Pglycoproteinmedieret fexofenadinefflux, når det ved samtidig administration medfører øget koncentration af fexofenadin.
English: Indinavir AUC24hr: 178 % Indinavir Cmin:11-fold; (Relative to Indinavir 800 mg TID alone*) Ritonavir AUC:  72 % Ritonavir Cmin:  62 %
Danish: Indinavir AUC24t: 178 % Indinavir Cmin:11 gange; (I forhold til indinavir 800 mg TID alene*) Ritonavir AUC:  72 % Ritonavir Cmin:  62 %
English: Nevirapine 200 mg BID (Indinavir 800 mg TID)
Danish: Nevirapin 200 mg BID (Indinavir 800 mg TID)
English: Although the etiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to combination antiretroviral therapy (CART).
Danish: Ætiologien anses dog for at være multifaktoriel (omfattende anvendelse af kortikosteroider, alkoholforbrug, svær immunsuppression, højere Body Mass Index (BMI)).
English: Herbal preparations containing St. John's wort are contraindicated with Crixivan.
Danish: Naturlægemidler, der indeholder perikon er kontraindiceret sammen med CRIXIVAN.
English: CALCIUM CHANNEL BLOCKERS Diltiazem 120 mg QD (Indinavir/ritonavir 800/100 BID)
Danish: CALCIUMANTAGONISTER Diltiazem 120 mg QD (Indinavir/ritonavir 800/100 BID
English: Vardenafil dose should not exceed a maximum of 2.5 mg in a 24-hour period in patients receiving concomitant indinavir therapy.
Danish: Vardenafil-dosis bør ikke overstige max. 2,5 mg i en 24-timers periode hos patienter, der samtidig får indinavirbehandling.
English: • The capsules are printed with printing ink containing titanium dioxide (E 171), indigo carmine (E 132) and iron oxide (E 172).
Danish: • Kapslerne er præget med blæk, der indeholder titandioxid (E171), indigocarmin (E132) og jernoxid (E172).
English: How to take CRIXIVAN
Danish: Sådan skal De tage CRIXIVAN
English: printing ink: titanium dioxide (E 171), indigo carmine (E 132) and iron oxide (E 172).
Danish: Kapselskal: gelatine titandioxid (E171) prægeblæk: Titandioxid (E 171), indigocarmin (E 132) og jernoxid (E 172).
English: Tadalafil dose should not exceed a maximum of 10 mg in a 72 hour period in patients receiving concomitant indinavir therapy.
Danish: Tadalafil-dosis bør ikke overstige max. 10 mg i en 72timers periode hos patienter, der samtidig får indinavirbehandling.
English: A greater than dose-proportional increase in indinavir plasma concentrations was observed over the 200 - 800 mg dose range.
Danish: Ved dosisintervallet 200-800 mg var øgningen i plasmakoncentrationerne større end dosisproportional.
English: Indinavir and fluconazole can be co-administered without dose adjustment.
Danish: Indinavir og fluconazol kan administreres samtidigt uden dosisjustering.
English: Indinavir and methadone can be co-administered without dose adjustment.
Danish: Indinavir og methadon kan administreres samtidigt uden dosisjustering.
English: CRIXIVAN with ritonavir and oral midazolam should not be coadministered (see section 4.3).
Danish: CRIXIVAN bør ikke administreres samtidigt med ritonavir og oral midazolam (see pkt.
English: CRIXIVAN 200 mg hard capsules
Danish: CRIXIVAN 200 mg hårde kapsler
English: CRIXIVAN 400 mg - packs of 90 and 180 capsules - Outer carton
Danish: CRIXIVAN 400 mg - pakning med 90 og 180 kapsler - Ydre æske
English: There are no interaction data available on the coadministration of indinavir/ritonavir and amprenavir.
Danish: administration af indinavir/ritonavir og amprenavir.
English: Indinavir AUC24hr:220 % Indinavir Cmin:↑ 24-fold (Relative to Indinavir 800 mg TID alone*) Ritonavir AUC24hr: 
Danish: Indinavir AUC24t:220 % Indinavir Cmin:↑ 24 gange (I forhold til indinavir 800 mg TID alene*) Ritonavir AUC24t: 
English: Ketoconazole 400 mg QD (Indinavir 600 mg TID)
Danish: Ketoconazol 400 mg QD (Indinavir 600 mg TID)
English: Careful monitoring of therapeutic and adverse effects is recommended when dexamethasone is concomitantly administered with indinavir.
Danish: Omhyggelig monitorering af terapeutisk virkning og bivirkninger anbefales, når dexamethason administreres samtidigt med indinavir.
English: Ketoconazole 400 mg QD (Indinavir 400 mg TID)
Danish: Ketoconazol 400 mg QD (Indinavir 400 mg TID)
English: Interaction not studied  dexamethasone exposure expected (CYP3A inhibition).
Danish:  dexamethasoneksponering forventelig (CYP3A-hæmning).
English: Concurrent use of indinavir with rifampicin or herbal preparations containing St John's wort (Hypericum perforatum) is contraindicated.
Danish: Samtidig brug af indinavir og rifampicin eller naturlægemidler med perikon (hypericum perforatum) er kontraindiceret).
English: Saquinavir 1,200 mg SD (soft gel capsule formulation) (Indinavir 800 mg TID)
Danish: Saquinavir 1200 mg SD (blød gelkapselformulering) (Indinavir 800 mg TID)
English: Indinavir AUC24hr:68 % Indinavir Cmin: ↑ 10-fold (Relative to Indinavir 800 mg TID alone*) Ritonavir AUC24hr: 
Danish: Indinavir AUC24t:68 % Indinavir Cmin: ↑ 10 gange (I forhold til indinavir 800 mg TID alene*) Ritonavir AUC24t: 
English: Indinavir and cimetidine can be co-administered without dose adjustment.
Danish: Indinavir og cimetidin kan administreres samtidigt uden dosisjustering.
English: Careful monitoring of therapeutic and adverse effects is recommended when erythromycin or itraconazole are concomitantly administered with indinavir/ritonavir.
Danish: Omhyggelig monitorering af terapeutiske virkninger og bivirkninger anbefales, når erythromycin eller itraconazol administreres samtidigt med indinavir/ritonavir.
English: Indinavir Cmin:  (Relative to Indinavir 800 mg TID alone)
Danish: Indinavir Cmin:  (I forhold til indinavir 800 mg TID alene)
English: Interaction with indinavir/ritonavir not studied Decreased indinavir concentrations and increased rifabutin concentrations are expected.
Danish: Nedsat indinavirkoncentration og øget rifabutinkoncentration er forventelig.
English: This means you will take a total of twelve 200 mg capsules (2400 mg) each day.
Danish: Dette betyder, at De i alt skal tage tolv 200 mg kapsler (2.400 mg) hver dag.
English: Interaction with indinavir/ritonavir not studied Ritonavir induces glucuronidation and as a result is expected to decrease the plasma concentrations of atovaquone.
Danish: Ritonavir inducerer glucuronidering og som følge heraf forventes fald i atovaquons plasmakoncentration.
English: CRIXIVAN with or without ritonavir should not be administered concurrently with amiodarone, terfenadine, cisapride, astemizole, quetiapine, alprazolam, triazolam, midazolam administered orally (for caution on parenterally administered midazolam, see section 4.5), pimozide, ergot derivatives, simvastatin or lovastatin (see section 4.4).
Danish: CRIXIVAN, med eller uden ritonavir, bør ikke administreres samtidigt med amiodaron, terfenadin, cisaprid, astemizol, quetiapin, alprazolam, triazolam, midazolam administreret peroralt (mht. forsigtighed ved parenteralt administreret midazolam se pkt.
English: CRIXIVAN 400 mg hard capsules
Danish: CRIXIVAN 400 mg hårde kapsler
English: Saquinavir 800 mg SD (soft gel capsule formulation) (Indinavir 800 mg TID)
Danish: Saquinavir 800 mg SD (blød gelkapselformulering) (Indinavir 800 mg TID)
English: Saquinavir 600 mg SD (hard gel capsule formulation) (Indinavir 800 mg TID)
Danish: Saquinavir 600 mg SD (hård gelkapselformulering) (Indinavir 800 mg TID)
English: In addition, when CRIXIVAN is given at the same time as the medicine ritonavir: Do not take either CRIXIVAN or ritonavir:
Danish: Når CRIXIVAN gives sammen med lægemidlet ritonavir:
English: Careful monitoring of serum levels or therapeutic effects is recommended when these medicines are concomitantly administered with indinavir/ritonavir.
Danish: Omhyggelig monitorering af serumkoncentrationen eller den terapeutiske virkning, når disse lægemidler administreres samtidigt med indinavir/ritonavir.
English: This means you will take a total of two 400 mg capsules (800 mg) each day.
Danish: Dette betyder, at De i alt skal tage to 400 mg kapsler (800 mg) hver dag.
English: Anhydrous lactose.
Danish: Lactose, vandfri.
English: Indinavir and isoniazid can be co-administered without dose adjustment.
Danish: Indinavir og isoniazid kan administreres samtidigt uden dosisjustering.
English: Interaction with indinavir/ritonavir not studied Morphine levels may be decreased due to induction of glucuronidation by coadministered ritonavir.
Danish: Morphinkoncentrationen kan falde på grund af induktion af glucuronidering i forbindelse med samtidig administration af ritonavir.
English: If you notice bleeding or if you feel weak, talk to your doctor straight away.
Danish: Kontakt straks Deres læge, hvis der opstår blødninger eller hvis De føler Dem svag.
English: This means you will take a total of six 400 mg capsules (2400 mg) each day.
Danish: Dette betyder, at De i alt skal tage seks 400 mg kapsler (2.400 mg) hver dag.
English: (including microscopic haematuria) occur, temporary interruption of therapy (e.g. for 1-3 days) during the acute episode of nephrolithiasis or discontinuation of therapy may be considered.
Danish: Hvis der opstår tegn og symptomer på nefrolitiasis, inklusive lændesmerter med eller uden hæmaturi (inklusive mikroskopisk hæmaturi), bør midlertidig seponering af behandling (fx 1-3 dage) under den akutte episode med nefrolitiasis eller seponering af behandling overvejes.
English: This means you will take a total of four 200 mg capsules (800 mg) each day.
Danish: Dette betyder, at De i alt skal tage fire 200 mg kapsler (800 mg) hver dag.
English: Dose reduction of CRIXIVAN to 600 mg every 8 hours is recommended with administering itraconazole concurrently.
Danish: Ved samtidig administration af itraconazol anbefales dosisreduktion af CRIXIVAN til 600 mg hver 8. time.
English: Concurrent use of indinavir with herbal preparations containing St John's wort (Hypericum perforatum) is contraindicated (see section 4.5).
Danish: Samtidig brug af indinavir og naturlægemidler med perikon (hypericum perforatum) er kontraindiceret (se pkt.
English: • pain on urination
Danish: • smerte ved vandladning
English: At steady state following a dose regimen of 800 mg every 8 hours, HIV-seropositive adult patients in one study achieved geometric means of: AUC0-8h of 27,813 nM*h (90 % confidence interval = 22,185, 34,869), peak plasma concentrations 11,144 nM (90 % confidence interval = 9,192, 13,512) and plasma concentrations at 8 hours post dose 211 nM (90 % confidence interval = 163,
Danish: Ved steady state efter et dosisregime på 800 mg/100 mg indinavir/ritonavirterapi hver 12. time i kombination med et fedtfattigt måltid, opnåedes i en undersøgelse følgende geometriske middelværdier: AUC0-12 timer på 116067 nM·t (90% konfidensinterval = 101680, 132490), maksimale plasmakoncentrationer på 19001 nM (90% konfidensinterval = 17538,
English: Fluconazole 400 mg QD (Indinavir 1,000 mg TID)
Danish: Antimykotika Fluconazol 400 mg QD (Indinavir 1000 mg TID)
English: Lactose
Danish: Pruritus
English: Possible side effects
Danish: Yderligere bivirkninger
English: CRIXIVAN 200 mg hard capsules indinavir
Danish: CRIXIVAN 200 mg hårde kapsler Indinavir
English: Careful monitoring of therapeutic and adverse effects is recommended when morphine is concomitantly administered with indinavir/ritonavir.
Danish: Omhyggelig monitorering af terapeutiske virkninger og bivirkninger anbefales, når morphin administreres samtidigt med indinavir/ritonavir.
English: Erythromycin, Itraconazole Interaction with indinavir/ritonavir not studied Indinavir and ritonavir inhibit CYP3A4 and as a result are expected to increase the plasma concentrations of erythromycin and itraconazole.
Danish: Indinavir og ritonavir hæmmer CYP3A4 og som følge heraf forventes de at øge erythromycins og itraconazols plasmakoncentrationer.
English: Indinavir and theophylline can be co-administered without dose adjustment.
Danish: Indinavir og theophyllin kan administreres samtidigt uden dosisjustering.