FrancophonIA/ELRC3.0 huggingface dataset:
English: • Switch between enoxaparin sodium and vitamin K antagonists (VKA) Clinical monitoring and laboratory tests [prothrombin time expressed as the International Normalized Ratio (INR)] must be intensified to monitor the effect of VKA.
Croatian: • Prelazak s enoksaparinnatrija na antagoniste vitamina K i obratno Kliničko praćenje i laboratorijske pretrage (protrombinsko vrijeme izraženo kao internacionalni normalizirani omjer [engl. international normalized ratio, INR] moraju se intenzivirati radi praćenja učinka antagonista vitamina K. Budući da je potrebno određeno vrijeme da antagonist vitamina
English: • Because of the content of benzyl alcohol (see section 6.1), enoxaparin sodium pen formulation must not be given to newborns or premature neonates (see sections 4.4 and 4.6).
Croatian: • budući da sadrži benzilni alkohol (vidjeti dio 6.1), formulacija enoksaparinnatrija u brizgalici ne smije se primijeniti u novorođenčadi i nedonoščadi (vidjeti dijelove 4.4 i 4.6)
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER BOX 10,000 IU/10 mL (100 mg/10 mL) VIAL
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU KUTIJA BOČICE OD 10 000 IU/10 ml (100 mg/10 ml)
English: For prefilled syringe PL: Instruction for use of the syringe [To be completed locally]
Croatian: Za uputu o lijeku za napunjenu štrcaljku: Upute za uporabu štrcaljke [ispunjava država članica]
English: LOVENOX (and associated names) can be used to:
Croatian: LOVENOX (i pridružena imena) se može koristiti za:
English: • Percutaneous coronary revascularization procedures To minimize the risk of bleeding following the vascular instrumentation during the treatment of unstable angina, NSTEMI and acute STEMI, adhere precisely to the intervals recommended between enoxaparin sodium injection doses.
Croatian: Kako bi se minimizirao rizik od krvarenja nakon krvožilnog pristupa tijekom liječenja nestabilne angine, NSTEMI-ja i akutnog STEMI-ja, treba se točno pridržavati preporučenih intervala između injekcijskih doza enoksaparinnatrija.
English: • you are going to receive spinal or epidural anesthesia or lumbar puncture (see Operations and Anaesthetics): a delay should be respected between Lovenox use and this procedure.
Croatian: • ako ćete primiti spinalnu ili epiduralnu anesteziju ili ići na lumbalnu punkciju (pogledajte odlomak 'Operacije i anestetici'): mora se poštovati vremenski razmak između primjene lijeka Lovenox i navedenih postupaka
English: INSTRUCTIONS ON USE [To be completed nationally]
Croatian: UPUTE ZA UPORABU: [Ispunjava država članica]
English: Multiple dose vials containing benzyl alcohol
Croatian: Višedozne bočice koje sadrže benzilni alkohol
English: Pharmacotherapeutic group: Antithrombotic agent, heparin group, ATC code: B01A B05
Croatian: ATK oznaka: B01A B05
English: Method of administration LOVENOX (and associated names) should not be administered by the intramuscular route.
Croatian: LOVENOX (i pridružena imena) ne smije se primijenjivati intramuskularnim putem.
English: The occurrence of total and major bleeding were respectively 8.6% and 1.1% in the placebo group, 11.7% and 0.3% in the enoxaparin sodium 2,000 IU (20 mg) group and 12.6% and 1.7% in the enoxaparin sodium 4,000 IU (40 mg) group.
Croatian: Stopa svih krvarenja i velikih krvarenja iznosila je 8,6% odnosno 1,1% u skupini koja je primala placebo, 11,7% odnosno 0,3% u skupini liječenoj enoksaparinnatrijem u dozi od 2000 IU (20 mg) te
English: • Spinal/Epidural anaesthesia or lumbar puncture Spinal/epidural anaesthesia or lumbar puncture must not be performed within 24 hours of administration of enoxaparin at therapeutic doses (see also section 4.3).
Croatian: • Spinalna/epiduralna anestezija ili lumbalna punkcija Spinalna/epiduralna anestezija ili lumbalna punkcija ne smiju se izvoditi unutar 24 sata od primjene enoksaparina u terapijskim dozama (vidjeti i dio 4.3).
English: Therefore, careful clinical monitoring is advised in these patients (see section
Croatian: Stoga se u tih bolesnika preporučuje pažljivo kliničko praćenje (vidjeti dio 5.2).
English: • Active clinically significant bleeding and conditions with a high risk of haemorrhage, including recent haemorrhagic stroke, gastrointestinal ulcer, presence of malignant neoplasm at high risk of bleeding, recent brain, spinal or ophthalmic surgery, known or suspected oesophageal varices, arteriovenous malformations, vascular aneurysms or major intraspinal or intracerebral vascular abnormalities;
Croatian: • aktivnim klinički značajnim krvarenjem i stanjima kod kojih postoji visok rizik od krvarenja, uključujući nedavno pretrpljen hemoragijski moždani udar, gastrointestinalni ulkus, prisutnost zloćudne novotvorine kod koje postoji visok rizik od krvarenja, nedavno proveden kirurški zahvat na mozgu, kralježnici ili očima, poznate ili suspektne varikozitete jednjaka, arteriovenske malformacije, krvožilne aneurizme ili značajne intraspinalne ili intracerebralne krvožilne abnormalnosti • spinalnom ili epiduralnom anestezijom ili lokoregionalnom anestezijom kada je enoksaparinnatrij primijenjen za liječenje unutar prethodna 24 sata (vidjeti dio 4.4)
English: • Stop blood clots from forming in your blood in the following situations: o Before and after an operation o When you have an acute illness and face period of limited mobility o When you have unstable angina (a condition when not enough blood gets to your heart) o After a heart attack
Croatian: o prije i nakon operacije o kada imate akutnu bolest i možda ćete neko vrijeme biti manje pokretni o kada imate nestabilnu anginu pektoris (stanje kod kojega do srca ne dospijeva dovoljna količina krvi) o nakon srčanog udara
English: No dose reduction is necessary in the elderly patients in haemodialysis indication.
Croatian: Nije potrebno prilagođavati dozu u starijih bolesnika kada se lijek koristi kod hemodijalize.
English: • For the prevention of thrombus formation in the extra corporeal circulation during haemodialysis,
Croatian: • Za sprječavanje nastanka krvnih ugrušaka u izvantjelesnoj cirkulaciji tijekom hemodijalize,
English: In patients with severe renal impairment (creatinine clearance <30 mL/min), the AUC at steady state is significantly increased on average by 65% after repeated SC 4,000 IU (40 mg) once daily doses (see sections 4.2 and 4.4).
Croatian: U bolesnika s teškim oštećenjem bubrežne funkcije (klirens kreatinina < 30 ml/min), AUC u stanju dinamičke ravnoteže značajno je povišen za prosječno 65% nakon ponovljene supkutane primjene doze od 4000 IU (40 mg) jedanput na dan (vidjeti dijelove 4.4 i 4.2).
English: All Treated Extended Prophylaxis Patients
Croatian: Svi liječeni bolesnici koji su primali produljenu profilaksu Ukupni VTE
English: • Large red irregularly shaped skin lesions with or without blisters.
Croatian: • velike crvene kožne lezije nepravilna oblika, koje mogu i ne moraju biti praćene mjehurićima na koži • nadraženost kože (lokalna iritacija)
English: You should tell your doctor straight away • If you have any sign of blockage of a blood vessel by a blood clot such as :
Croatian: • Ako imate bilo koji znak začepljenja krvne žile krvnim ugruškom, kao što su:
English: Multiple dose vials containing benzyl alcohol:
Croatian: Višedozne bočice koje sadrže benzilni alkohol:
English: 6.6 Special precautions for disposal and other handling INSTRUCTIONS FOR USE: PREFILLED SYRINGE [To be completed nationally]
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom UPUTE ZA UPORABU: NAPUNJENA ŠTRCALJKA
English: See “Do not use LOVENOX (and associated names)”.
Croatian: Pogledajte odlomak "Nemojte primjenjivati LOVENOX (i pridružena imena)".
English: The risk of these events is higher with the use of post-operative indwelling epidural catheters, with the concomitant use of additional drugs affecting haemostasis such as NonSteroidal Anti-Inflammatory Drugs (NSAIDs), with traumatic or repeated epidural or spinal puncture, or in patients with a history of spinal surgery or spinal deformity.
Croatian: Rizik od tih događaja veći je kod uporabe poslijeoperacijskih trajnih epiduralnih katetera, istodobne primjene dodatnih lijekova koji utječu na hemostazu, poput nesteroidnih protuupalnih lijekova (NSAIL), traumatske ili ponovljene epiduralne ili spinalne punkcije, kao i u bolesnika koji u anamnezi imaju kirurški zahvat na kralježnici ili deformaciju kralježnice.
English: [to be completed nationally]
Croatian: [Ispunjava država članica]
English: Initiate dosing with 75 IU/kg (0.75 mg/kg) SC every 12 hours (maximum 7,500 IU (75 mg) for each of the first two SC doses only, followed by 75 IU/kg (0.75 mg/kg) SC dosing for the remaining doses).
Croatian: (0,75 mg/kg) svakih 12 sati (najviše 7500 IU [75 mg] samo za svaku od prve dvije supkutane doze,
English: LOVENOX (and associated names) 12,000 IU (120 mg)/0.8 mL solution for injection LOVENOX (and associated names) 15,000 IU (150 mg)/1 mL solution for injection
Croatian: LOVENOX (i pridružena imena) 12 000 IU (120 mg)/0,8 ml otopina za injekciju LOVENOX (i pridružena imena) 15 000 IU (150 mg)/1 ml otopina za injekciju
English: In patients with severe renal impairment (creatinine clearance <30 mL/min), the AUC at steady state is significantly increased on average by 65% after repeated SC 4,000 IU (40 mg) once daily doses (see section 4.4).
Croatian: U bolesnika s teškim oštećenjem bubrežne funkcije (klirens kreatinina < 30 ml/min), AUC u stanju dinamičke ravnoteže značajno je povišen za prosječno 65% nakon ponovljene supkutane primjene doze od 4000 IU (40 mg) jedanput na dan (vidjeti dio 4.4).
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE(S) OF ADMINISTRATION LOVENOX 10 x 4,000 IU (10 x 40 mg) Pen enoxaparin
Croatian: NAZIV LIJEKA I PUT(EVI) PRIMJENE LIJEKA LOVENOX 10 x 4000 IU (10 x 40 mg) brizgalica enoksaparin
English: Treatment of acute STEMI (patients under 75)
Croatian: Liječenje akutnog STEMI-ja (bolesnici mlađi od
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS 10,000 IU/10 mL (100 mg/10 mL) VIAL
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE BOČICA OD 10 000 IU/10 ml (100 mg/10 ml)
English: How to store LOVENOX (and associated names) [To be completed nationally]
Croatian: Kako čuvati LOVENOX (i pridružena imena) [Ispunjava država članica]
English: What LOVENOX (and associated names) looks like and contents of the pack
Croatian: Kako LOVENOX (i pridružena imena) izgleda i sadržaj pakiranja
English: [To be completed nationally] [See Annex I - To be completed nationally]
Croatian: [Ispunjava država članica] [Vidjeti Prilog I.
English: For patients have an operation called percutaneous coronary intervention (PCI): Depending on when you were last given LOVENOX (and associated names), your doctor may decide to give an additional dose of LOVENOX (and associated names) before a PCI operation.
Croatian: • Ovisno o tome kad ste zadnji put primili LOVENOX (i pridružena imena), Vaš će liječnik možda odlučiti primijeniti dodatnu dozu lijeka LOVENOX (i pridružena imena) prije perkutane koronarne intervencije.
English: However, since renal function is known to decline with age, elderly patients may show reduced elimination of enoxaparin sodium (see section 4.4).
Croatian: Međutim, poznato je da se bubrežna funkcija smanjuje s porastom dobi, pa eliminacija enoksaparinnatrija može biti smanjena u starijih bolesnika (vidjeti dio 4.4).
English: If a manual compression method is used, sheath should be removed 6 hours after the last IV/SC enoxaparin sodium injection.
Croatian: uvodnicu treba ukloniti 6 sati nakon posljednje i.v./s.c. injekcije enoksparinnatrija.
English: What LOVENOX (and associated names) looks like and contents of the pack [To be completed nationally]
Croatian: Kako LOVENOX (i pridružena imena) izgleda i sadržaj pakiranja [Ispunjava država članica]
English: • Common: Injection site haematoma, injection site pain, other injection site reaction (such as oedema, haemorrhage, hypersensitivity, inflammation, mass, pain, or reaction)
Croatian: Opći poremećaji i reakcije na mjestu primjene • Često: hematom na mjestu injiciranja, bol na mjestu injiciranja, ostale reakcije na mjestu injiciranja (kao što su edem, krvarenje, preosjetljivost, upala, masa, bol ili reakcija)
English: These included 1776 for prophylaxis of deep vein thrombosis following orthopaedic or abdominal surgery in patients at risk for thromboembolic complications, 1,169 for prophylaxis of deep vein thrombosis in acutely ill medical patients with severely restricted mobility, 559 for treatment of DVT with or without PE, 1,578 for treatment of unstable angina and non-Q-wave myocardial infarction and 10,176 for treatment of acute STEMI.
Croatian: To je uključivalo 1776 slučajeva profilakse duboke venske tromboze nakon ortopedskog ili abdominalnog kirurškog zahvata u bolesnika s rizikom od tromboembolijskih komplikacija, 1169 slučajeva profilakse duboke venske tromboze u medikamentozno liječenih bolesnika s akutnom bolešću i izuzetno ograničenom pokretljivošću, 559 slučajeva liječenja DVT-a praćenog PE-om ili bez njega, 1578 slučajeva liječenja nestabilne angine i infarkta miokarda bez Q-zupca te 10 176 slučajeva liječenja akutnog STEMI-ja.
English: Do not use LOVENOX (and associated names)
Croatian: Nemojte primjenjivati LOVENOX (i pridružena imena)
English: This helps your body to break them down and stops them from causing you harm2) Stopping blood clots from forming in your blood.
Croatian: Time pomaže tijelu da ih razgradi i sprječava štetu koju bi Vam oni mogli nanijeti.
English: One vial (3.0 mL) contains 30,000 IU (300 mg) enoxaparin sodium One vial (5.0 mL) contains 50,000 IU (500 mg) enoxaparin sodium One vial (10.0 mL) contains 100,000 IU (1,000 mg) enoxaparin sodium
Croatian: Jedna bočica (3,0 ml) sadrži 30 000 IU (300 mg) enoksaparinnatrija Jedna bočica (5,0 ml) sadrži 50 000 IU (500 mg) enoksaparinnatrija Jedna bočica (10,0 ml) sadrži 100 000 IU (1000 mg) enoksaparinnatrija
English: In the clinical studies for treatment of unstable angina and non-Q-wave myocardial infarction, doses were 100 IU/kg (1 mg/kg) SC every 12 hours, and in the clinical study for treatment of acute STEMI enoxaparin sodium regimen was a 3,000 IU (30 mg) IV bolus followed by 100 IU/kg (1 mg/kg) SC every 12 hours.
Croatian: U kliničkim ispitivanjima primjene za liječenje nestabilne angine i infarkta miokarda bez Q-zupca, doza je iznosila 100 IU/kg (1 mg/kg) s.c. svakih 12 sati, dok je u kliničkom ispitivanju primjene za liječenje akutnog STEMI-ja režim liječenja enoksaparinnatrijem uključivao primjenu intravenske bolusne doze od 3000 IU
English: To obtain a 300 IU/mL (3 mg/mL) solution, using a 6,000 IU (60 mg) enoxaparin sodium pre-filled syringe, it is recommended to use a 50 mL infusion bag (i.e. using either normal saline solution (0.9%) or 5% dextrose in water) as follows:
Croatian: (60 mg) enoksaparinnatrija, preporučuje se upotrijebiti infuzijsku vrećicu volumena 50 ml (s fiziološkom otopinom [0,9%] ili vodenom otopinom glukoze [5%]) na sljedeći način:
English: Acetylsalicylic acid is recommended for all patients without contraindications at an initial oral loading dose of 150-300 mg (in acetylsalicylic acid-naive patients) and a maintenance dose of 75325 mg/day long-term regardless of treatment strategy.
Croatian: uz početnu peroralnu udarnu dozu od 150 do 300 mg (u bolesnika koji prethodno nisu bili liječeni acetilsalicilatnom kiselinom) i dugoročnu terapiju održavanja dozom od 75 do 325 mg/dan, neovisno o strategiji liječenja.
English: LOVENOX (and associated names) contains the active substance called enoxaparin sodium that is a low molecular weight heparin (LMWH).
Croatian: Što je LOVENOX (i pridružena imena) i za što se koristi LOVENOX (i pridružena imena) sadrži djelatnu tvar koja se zove enoksaparinnatrij, a koja pripada skupini heparina niske molekulske mase.
English: What LOVENOX (and associated names) is and what it is used for
Croatian: Što se nalazi u ovoj uputi Što je LOVENOX (i pridružena imena) i za što se koristi
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER BOX AMPOULE
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU KUTIJA AMPULE
English: LOVENOX (and associated names) in a pen can be used to:
Croatian: LOVENOX (i pridružena imena) u brizgalici može se koristiti za:
English: • Rare: Cholestatic liver injury*
Croatian: • Manje često: hepatocelularno oštećenje jetre* • Rijetko: kolestatsko oštećenje jetre*
English: All Treated Medical Patients During Acute Illness Total VTE (%)
Croatian: Svi medikamentozno liječeni bolesnici koji su primali terapiju tijekom akutne bolesti
English: METHOD OF ADMINISTRATION SC / IV
Croatian: s.c./i.v.
English: Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency.
Croatian: Biotransformacija Enoksaparinnatrij se prvenstveno metabolizira u jetri procesima desulfatacije i/ili depolimerizacije,
English: 15,000 IU/mL (150 mg/mL) solution for injection:
Croatian: 15 000 IU/ml (150 mg/ml) otopina za injekciju:
English: 10,000 IU/mL (100 mg/mL) solution for injection:
Croatian: 10 000 IU/ml (100 mg/ml) otopina za injekciju:
English: LOVENOX (and associated names) is indicated in adults for:
Croatian: 4.1 Terapijske indikacije LOVENOX (i pridružena imena) je indiciran u odraslih za:
English: Careful clinical monitoring is advised and dose reduction might be considered in patients older than 75 years treated for STEMI (see sections 4.2 and
Croatian: U bolesnika starijih od 75 godina koji se liječe zbog STEMI-ja preporučuje se pažljivo kliničko praćenje, a može se razmotriti i smanjenje doze (vidjeti dijelove 4.2 i 5.2).
English: The treatment benefits of enoxaparin sodium, evident for a number of efficacy outcomes, emerged at 48 hours, at which time there was a 35 percent reduction in the relative risk of myocardial reinfarction, as compared with treatment with unfractionated heparin (p<0.001).
Croatian: Terapijska korist enoksaparinnatrija, koja je primijećena kod niza ishoda djelotvornosti, nastupila je nakon 48 sati, kada je zabilježeno smanjenje relativnog rizika od ponovljenog infarkta miokarda za
English: LOVENOX (and associated names) 30,000 IU (300 mg)/3 mL solution for injection LOVENOX (and associated names) 50,000 IU (500 mg)/5 mL solution for injection LOVENOX (and associated names) 100,000 IU (1,000 mg)/10 mL solution for injection
Croatian: LOVENOX (i pridružena imena) 30 000 IU (300 mg)/3 ml otopina za injekciju LOVENOX (i pridružena imena) 50 000 IU (500 mg)/5 ml otopina za injekciju LOVENOX (i pridružena imena) 100 000 IU (1000 mg)/10 ml otopina za injekciju
English: Hepatic impairment
Croatian: - poremećaj hemostaze
English: One 3.0 mL pen contains enoxaparin sodium 40,000 IU anti-Xa activity (equivalent to 400 mg), equivalent to 10 single doses of 4,000 IU (40 mg) enoxaparin sodium, + 45 mg benzyl alcohol in 3.0 mL water for injections
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedna brizgalica od 3,0 ml sadrži 40 000 IU anti-Xa aktivnosti enoksaparinnatrija (što odgovara 400 mg), što odgovara 10 pojedinačnih doza od 4000 IU (40 mg) enoksaparinnatrija, + 45 mg benzilnog alkohola u 3,0 ml vode za injekcije.
English: For patients with creatinine clearance [15-30] mL/min, consider doubling the timing of puncture/catheter placement or removal to at least 48 hours.
Croatian: U bolesnika s klirensom kreatinina od 15 do30 ml/min, razmotrite udvostručenje vremena do uboda/uvođenja ili uklanjanja katetera na najmanje 48 sati.
English: For continuous techniques, a similar delay of at least 12 hours should be observed before removing the catheter.
Croatian: Kada se koriste kontinuirane tehnike, prije uklanjanja katetera također mora proći najmanje
English: • Skin necrosis / cutaneous vasculitis
Croatian: tinzaparin ili dalteparin
English: 15,000 IU/mL (150 mg/mL) solution for injection
Croatian: 15 000 IU/ml (150 mg/ml) otopina za injekciju
English: For patients with creatinine clearance [15-30] mL/min, consider doubling the timing of puncture/catheter placement or removal to at least 24 hours.
Croatian: U bolesnika s klirensom kreatinina od 15 do30 ml/min, razmotrite udvostručenje vremena do uboda/uvođenja ili uklanjanja katetera na najmanje 24 sata.
English: {Name and Address} {tel} {fax} {e-mail}
Croatian: {Naziv države članice} {Naziv lijeka} {Naziv države članice} {Naziv lijeka}
English: One vial contains enoxaparin sodium 50,000 IU anti-Xa activity (equivalent to 500 mg) + 75 mg benzyl alcohol in 5.0 mL water for injections.
Croatian: Jedna bočica sadrži 50 000 IU anti-Xa aktivnosti enoksaparinnatrija (što odgovara 500 mg) + 75 mg benzilnog alkohola u 5,0 ml vode za injekcije.
English: Limited data are available in patients with hepatic impairment (see sections 5.1 and 5.2) and caution should be used in these patients (see section 4.4).
Croatian: i 5.2) i stoga je u tih bolesnika potreban oprez (vidjeti dio 4.4).
English: Ampoules
Croatian: Ampule
English: A puncture-free interval of at least 24 hours shall be kept between the last injection of enoxaparin sodium at curative doses and the needle or catheter placement (see also section 4.3).
Croatian: Između posljednje injekcije enoksaparinnatrija u terapijskim dozama i uvođenja igle ili katetera mora proći razdoblje od najmanje 24 sata bez ikakvih uboda (vidjeti i dio 4.3).
English: Multiple Dose Vials:
Croatian: Višedozne bočice:
English: For patients with creatinine clearance [15-30 mL/minute], additional considerations are necessary because elimination of enoxaparin sodium is more prolonged.
Croatian: Potrebno je dodatno razmotriti primjenu u bolesnika kojima je klirens kreatinina 15 - 30 ml/min jer je kod njih eliminacija enoksaparina dugotrajnija.
English: Treatment of deep vein thrombosis with or without pulmonary embolism In a multicenter, parallel group study, 900 patients with acute lower extremity DVT with or without PE were randomized to an inpatient (hospital) treatment of either (i) enoxaparin sodium 150 IU/kg (1.5 mg/kg) once a day SC, (ii) enoxaparin sodium 100 IU/kg (1 mg/kg) every 12 hours SC, or (iii) heparin IV bolus (5,000 IU) followed by a continuous infusion (administered to achieve an aPTT of 55 to 85 seconds).
Croatian: enoksaparinnatrijem u dozi od 150 IU/kg (1,5 mg/kg) s.c. jedanput na dan, (ii) enoksaparinnatrijem u dozi od 100 IU/kg (1 mg/kg) s.c. svakih 12 sati ili (iii) intravenskim bolusom heparina (5000 IU) nakon kojega je uslijedila kontinuirana infuzija (primijenjena radi postizanja aPTV-a od 55 do 85 sekundi).
English: In patients with severe renal impairment (creatinine clearance 15-30 mL/min), since exposure of enoxaparin sodium is significantly increased, a dosage adjustment is recommended for therapeutic and prophylactic dosage ranges.
Croatian: Zbog značajno povećane izloženosti enoksaparinnatriju u bolesnika s teškim oštećenjem bubrežne funkcije (klirens kreatinina: 15 - 30 ml/min), preporučuje se prilagoditi doze u terapijskom i profilaktičkom rasponu.
English: Your doctor will request you perform blood tests called INR and tell you when to start LOVENOX (and associated names) accordingly.
Croatian: Vaš će liječnik tražiti da napravite krvne pretrage za određivanje parametra koji se zove INR i reći će Vam kada trebate početi primjenjivati
English: For acute STEMI, treatment is to be initiated with a single IV bolus injection immediately followed by a SC injection.
Croatian: Kod akutnog STEMI-ja, liječenje treba započeti jednokratnom intravenskom bolusnom injekcijom,