FrancophonIA/ELRC3.0 huggingface dataset:
English: Orion Pharma S.L.
Croatian: UAB Orion Pharma Tel.
English: United Kingdom Orion Pharma (UK) Ltd. Tel: +44 1635 520 300
Croatian: Lifepharma (ZAM) Ltd Τηλ.: +357 22056300
English: Two of these studies included children.
Croatian: Dva ta ispitivanja uključivala su djecu.
English: This summary was last updated in 11-2013.
Croatian: Sažetak je posljednji put ažuriran 11.2013.
English: Opatanol can be used for up to four months, if needed.
Croatian: Opatanol se može koristiti do četiri mjeseca ako je potrebno.
English: Opatanol is used in adults and children aged three years and older.
Croatian: Opatanol se koristi u odraslih osoba i djece u dobi od tri godine i starije.
English: Opatanol has been studied in 688 patients in four main studies lasting between six and 14 weeks.
Croatian: Opatanol se ispitivao u 688 bolesnika u četiri glavna ispitivanja koja su trajala između šest i 14 tjedana.
English: The full EPAR for Opatanol can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Croatian: Cjelovito Europsko javno izvješće o ocjeni dokumentacije o lijeku (EPAR) za Opatanol nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: Opatanol olopatadine
Croatian: Opatanol olopatadin
English: The medicine can only be obtained with a prescription.
Croatian: Ovaj se lijek izdaje samo na recept.
English: Therefore care should be taken by people who wear soft contact lenses.
Croatian: Stoga osobe koje nose kontaktne leće moraju obratiti pozornost.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Opatanol on 17 May 2002.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje za lijek Opatanol vrijedi na prostoru Europske unije od 17. svibnja 2002.
English: When the receptors are blocked, histamine cannot have its effect, and this leads to a decrease in the symptoms of allergy.
Croatian: Kada su receptori blokirani, histamin ne može djelovati, a to rezultira smanjenjem simptoma alergije.
English: Other information about Opatanol
Croatian: Ostale informacije o lijeku Opatanol
English: At lower pollen counts, there were no differences between the two treatments.
Croatian: Pri manjoj količini cvjetne peludi, nije bilo razlike između ta dva liječenja.
English: The most common side effects with Opatanol (seen in between 1 and 10 patients in 100) are headache, dysgeusia (taste disturbances), eye pain, eye irritation, dry eyes, abnormal sensations in the eye, dry nose and fatigue (tiredness).
Croatian: Najčešće nuspojave lijeka Opatanol (primijećene kod 1 do 10 na 100 osoba) su glavobolja, dizgeuzija (poremećaj osjeta okusa), bol u oku, nadraženost oka, suhe oči, abnormalni osjeti u oku, suhi nos i iscrpljenost (umor).
English: If another eye treatment is also being used, there should be a gap of five minutes between treatments; eye ointments should be administered last.
Croatian: Ako se koristi druga terapija za oči, potreban je razmak od pet minuta između dvije terapije; posljednje se trebaju primjenjivati masti za oči.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Opatanol.
Croatian: Objašnjava kako je Povjerenstvo za lijekove za primjenu kod ljudi (CHMP) ocijenilo lijek da bi donijelo svoje mišljenje u korist davanja odobrenja za stavljanje lijeka u promet i svoje preporuke o uvjetima za primjenu lijeka Opatanol.
English: This is a summary of the European public assessment report (EPAR) for Opatanol.
Croatian: Ovo je sažetak Europskoga javnog izvješća o ocjeni dokumentacije o lijeku (EPAR) za Opatanol.
English: For more information about treatment with Opatanol, read the package leaflet (also part of the EPAR) or contact your doctor of pharmacist.
Croatian: Više informacija o terapiji lijekom Opatanol pročitajte u uputama o lijeku (također dio EPAR-a), odnosno obratite se svom liječniku ili ljekarniku.
English: Opatanol was as effective as cromolyn sodium and as levocabastine.
Croatian: Opatanol je bio jednako djelotvoran kao kromolin-natrij i kao levokabastin.
English: Opatanol was compared with cromolyn sodium (another anti-allergy medicine), with levocabastine (another antihistamine) and, in two studies, with placebo (a dummy treatment).
Croatian: Opatanol je uspoređen s kromolin-natrijem (drugim antialergijskim lijekom), s levokabastinom (drugim antihistaminikom) te, u dva ispitivanja, s placebom (lažnim liječenjem).
English: What is the risk associated with Opatanol?
Croatian: Koji su rizici povezani s lijekom Opatanol?
English: When compared with placebo, Opatanol was more effective only when pollen counts were taken into account, showing that the higher the level of pollen in the air, the greater the difference between the effects of Opatanol and those of placebo.
Croatian: Kada je uspoređen s placebom, Opatanol je bio djelotvorniji samo ako je količina cvjetne peludi uzeta u obzir, što dokazuje da što je količina cvjetne peludi u zraku veća, to je veća razlika između djelovanja lijeka Opatanol i placeba.
English: The active substance in Opatanol, olopatadine, is an antihistamine.
Croatian: Djelatna tvar u lijeku Opatanol, olopatadin, je antihistaminik.
English: These include itching, redness and swelling.
Croatian: Ti simptomi uključuju svrbež, crvenilo i oticanje.
English: Why has Opatanol been approved?
Croatian: Zašto je Opatanol odobren?
English: Opatanol contains benzalkonium chloride, which is known to discolour soft contact lenses.
Croatian: Opatanol sadrži benzalkonijev klorid, za koji je poznato da mijenja boju mekih kontaktnih leća.
English: Olopatadine works by blocking the receptors on which histamine, a substance in the body that causes allergic symptoms, normally attaches itself.
Croatian: Olopatadin djeluje blokirajući receptore na koje se normalno veže histamin, tvar u tijelu koja uzrokuje alergijske simptome.
English: The CHMP decided that Opatanol's benefits are greater than its risks for the treatment of ocular signs and symptoms of seasonal allergic conjunctivitis and recommended that it be given marketing authorisation.
Croatian: CHMP je odlučio da koristi od lijeka Opatanol nadmašuju s njim povezane rizike za liječenje okularnih znakova i simptoma sezonskog alergijskog konjunktivitisa te je preporučio izdavanje odobrenja za stavljanje lijeka u promet.
English: Opatanol is used to treat the eye symptoms of seasonal allergic conjunctivitis (inflammation of the eyes caused by pollen in patients with hayfever).
Croatian: Opatanol se koristi za liječenje okularnih simptoma sezonskog alergijskog konjunktivitisa (upale očiju uzrokovane cvjetnom peludi u bolesnika s peludnom groznicom).
English: It is given as one drop into the affected eye(s) twice a day, given eight hours apart.
Croatian: Primjenjuje se kao jedna kapljica u (svako) zahvaćeno oko dva puta na dan u razmaku od osam sati.
English: What is Opatanol?
Croatian: Što je Opatanol?
English: Opatanol is a clear eye drop solution, which contains the active substance olopatadine.
Croatian: Opatanol je bistra otopina za kapi za oči, koja sadrži djelatnu tvar olopatadin.
English: How does Opatanol work?
Croatian: Kako Opatanol djeluje?
English: What benefit has Opatanol shown during the studies?
Croatian: Koje su koristi lijeka Opatanol dokazane u ispitivanjima?
English: What is Opatanol used for?
Croatian: Za što se Opatanol koristi?
English: For the full list of all side effects reported with Opatanol, see the Package Leaflet.
Croatian: Potpuni popis nuspojava zabilježenih pri primjeni lijeka Opatanol, potražite u uputi o lijeku.
English: In all of the studies, the main measure of effectiveness was based on the degree of itching and redness in the eye. One of the placebo studies also looked at these symptoms in relation to pollen counts.
Croatian: U svim ovim ispitivanjima, glavna mjera djelotvornosti temeljila se na stupnju svrbeži i crvenila očiju.
English: How has Opatanol been studied?
Croatian: Kako se Opatanol ispitivao?
English: How is Opatanol used?
Croatian: Kako se Opatanol koristi?
English: This normally takes several seconds.
Croatian: To obično traje nekoliko sekundi.
English: c p-value for PGI-C is nominal.
Croatian: c p-vrijednost za PGI-C je nominalna.
English: You could put yourself or others at risk of serious injury or death.
Croatian: Inače biste mogli izložiti sebe ili druge riziku od ozbiljne ozljede ili smrti.
English: Results are presented in Table 2.
Croatian: Rezultati su prikazani u tablici 2.
English: Godfried Bomansstraat 31 6543 JA Nijmegen Netherlands
Croatian: Godfried Bomansstraat 31 6543 JA Nijmegen Nizozemska
English: During off periods your usual medicine does not control the condition well enough and movement is likely to be more difficult.
Croatian: Za vrijeme off razdoblja, Vaš uobičajeni lijek ne kontrolira stanje dovoljno dobro i pokreti će vjerojatno biti otežani.
English: Daily doses (median)
Croatian: Dnevne doze (medijan)
English: For more information see section 4.
Croatian: Za više informacija pogledajte dio 4.
English: Most of the gender difference is accounted for by differences in body weight.
Croatian: Veći dio razlike po spolu pripisuje se razlici u tjelesnoj težini.
English: Find a clean and dry surface.
Croatian: Pronađite čistu i suhu površinu.
English: Do not use any capsule that looks crushed, damaged or wet.
Croatian: Nemojte primijeniti kapsulu koja izgleda zdrobljeno, oštećeno ili vlažno.
English: See also under “Other medicines and Inbrija”.
Croatian: Pogledajte također pod „Drugi lijekovi i Inbrija“.
English: Your doctor may need to review your treatments.
Croatian: Vaš će liječnik možda morati ponovno procijeniti Vaše terapije.
English: Much improved % (n) Improved % (n) Little improved % (n) Not improved % (n) p-value
Croatian: Znatno poboljšano % (n) Poboljšano % (n) Malo poboljšano % (n) Bez poboljšanja % (n)
English: Do not push the handle and mouthpiece together more than once.
Croatian: Nemojte pritisnuti usnik i držak jedan prema drugome više od jedanput.
English: You may feel confused or agitated, and your heart rate may be slower or faster than normal.
Croatian: Možete se osjećati smeteno ili uznemireno, a rad srca može Vam biti sporiji ili brži nego što je to normalno.
English: • It is normal for some powder to remain on the inhaler.
Croatian: • Normalno je da nešto praška ostane na inhalatoru.
English: Daily OFF-time (h)
Croatian: Dnevno OFF razdoblje (h)
English: Make sure your hands are clean and dry.
Croatian: Pazite da Vam ruke budu čiste i suhe.
English: If you use more Inbrija than you should
Croatian: Ako primijenite više Inbrije nego što ste trebali
English: This may cause difficulties in breathing or swallowing.
Croatian: To može izazvati teškoće s disanjem i gutanjem.
English: Furthermore, a reduction of dose or termination of therapy may be considered.
Croatian: Nadalje, može se razmotriti smanjenje doze ili prekid terapije.
English: The mouthpiece will spring back and stay attached.
Croatian: Usnik će se vratiti u svoj položaj i ostati spojen.
English: This is because the medicine may affect the results of some tests.
Croatian: To je zato što lijek može utjecati na rezultate nekih pretraga.
English: If you use more Inbrija than you should (or someone accidentally swallows Inbrija) get medical help immediately.
Croatian: Ako primijenite više Inbrije nego što ste trebali (ili netko slučajno proguta Inbriju), odmah potražite medicinsku pomoć.
English: You will need it later to store the inhaler.
Croatian: Trebat će Vam kasnije kada budete spremali inhalator.
English: Epidemiological studies have shown that patients with Parkinson's disease have a higher risk (2- to approximately 6-fold higher) of developing melanoma than the general population.
Croatian: Epidemiološka ispitivanja pokazala su da bolesnici s Parkinsonovom bolešću imaju veći rizik (2 do otprilike 6 puta veći) za razvoj melanoma nego opća populacija.
English: Ready for storage
Croatian: Spremno za čuvanje
English: Sudden onset of sleep during daily activities, in some cases without awareness or warning signs, has been reported very rarely.
Croatian: Iznenadni nastupi sna tijekom dnevnih aktivnosti, u nekim slučajevima nesvjesni i bez znakova upozorenja, zabilježeni su vrlo rijetko.
English: Tell your doctor if you experience any of these behaviours; they will discuss ways of managing or reducing the symptoms.
Croatian: Obavijestite svog liječnika ako imate bilo koje od tih ponašanja; on će razmotriti načine liječenja ili ublažavanja tih simptoma.
English: Paranoia,
Croatian: paranoja,
English: If the off period has passed, do not use Inbrija until the next off period.
Croatian: Ako je off razdoblje prošlo, nemojte primijeniti Inbriju sve do sljedećeg off razdoblja.
English: What Inbrija is and what it is used for 2.
Croatian: Što je Inbrija i za što se koristi 2.
English: After 12 months, the average reduction in FEV1 from baseline was the same in both groups (-0.1 L).
Croatian: Nakon 12 mjeseci, prosječno smanjenje FEV1 u odnosu na početne vrijednosti bilo je jednako u obje skupine (-0,1 l).
English: Repeat Steps 4 to 10 with the second capsule to finish the full dose.
Croatian: Ponovite korake od 4. do 10. s drugom kapsulom kako biste uzeli punu dozu.
English: % (n) Diff. p-value
Croatian: % (n) Razlika p vrijednost
English: The maximum time between inhalation of the powder from the first and second capsules should not exceed 10 minutes.
Croatian: Maksimalno vrijeme između inhalacije praška iz prve i druge kapsule ne smije biti duže od 10 minuta.
English: Do not breathe into mouthpiece.
Croatian: Nemojte disati u usnik.
English: 2 doses a Observed cases.
Croatian: 2 doze a Promatrani slučajevi.
English: Please see the “Instructions for use” at the end of this leaflet on how to use your medicine with the provided inhaler.
Croatian: Pogledajte „Upute za uporabu” na kraju ove upute o lijeku za informacije o tome kako primjenjivati ovaj lijek pomoću priloženog inhalatora.
English: This may damage the capsule, and you may not get your full dose.
Croatian: Time možete oštetiti kapsulu i tako ne primiti punu dozu.
English: - When you open a new carton, always use the new inhaler supplied.
Croatian: - Kada otvorite novu kutiju lijeka, uvijek koristite novi priloženi inhalator.
English: Take your dose
Croatian: Uzmite svoju dozu
English: Make sure the mouthpiece is securely attached and will not fall off before moving to Step 7.
Croatian: Provjerite da je usnik čvrsto spojen i da se neće odvojite prije nego krenete na 7. korak.
English: Patients who are taking these medicinal products should be monitored closely.
Croatian: Bolesnike koji uzimaju ove lijekove mora se pažljivo nadzirati.
English: Due to cough, 2% of subjects withdrew from the clinical studies with Inbrija.
Croatian: Zbog kašlja se 2% ispitanika povuklo iz kliničkih ispitivanja s Inbrijom.
English: Step 9: Hold breath for 5 seconds, then breathe out
Croatian: 9. korak: Zadržite dah 5 sekundi, zatim izdahnite
English: The maximum daily dose of Inbrija should not exceed 10 capsules (330 mg).
Croatian: Maksimalna dnevna doza Inbrije ne smije biti viša od 10 kapsula (330 mg).
English: What Inbrija looks like and contents of the pack
Croatian: Kako Inbrija izgleda i sadržaj pakiranja
English: Malaise,
Croatian: svrbež,
English: Other medicines and Inbrija
Croatian: Drugi lijekovi i Inbrija
English: - Your doctor or pharmacist will show you how to use your medicine correctly.
Croatian: - Liječnik ili ljekarnik pokazat će Vam kako ispravno primjenjivati lijek.
English: This reaction will not be altered by boiling the urine specimen.
Croatian: Reakcija se ne mijenja ni ako se uzorak urina prokuha.
English: You can use 2 capsules up to five times a day.
Croatian: Smijete primijeniti po 2 kapsule do pet puta na dan.
English: Prepare your dose
Croatian: Pripremite svoju dozu
English: Local or systemic pulmonary medicinal products
Croatian: Lokalni ili sistemski lijekovi za pluća
English: Frequency categories are defined as follows: very common (≥1/10), common (≥1/100 to <1/10), not known
Croatian: Kategorije učestalosti definirane su kako slijedi: vrlo često (≥1/10), često (≥1/100 i <1/10), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Levodopa is extensively metabolised to various metabolites.
Croatian: Levodopa se opsežno metabolizira do različitih metabolita.
English: Malignant melanoma
Croatian: maligni melanom
English: Concurrent use can, however, cause a worsening of involuntary motor disorders.
Croatian: Istodobna primjena može, međutim, izazvati pogoršanje nevoljnih motoričkih poremećaja.
English: In addition, certain medicinal products used to treat psychosis may exacerbate the symptoms of Parkinson's disease and may decrease the effectiveness of levodopa.
Croatian: Osim toga, neki lijekovi koji se koriste u liječenju psihoze mogu pogoršati simptome Parkinsonove bolesti i mogu smanjiti učinkovitost levodope.
English: You must be sure that you do not get sudden sleep attacks, dizziness and drowsiness before you drive again or use machines.
Croatian: Morate biti sigurni da više nemate iznenadne napadaje spavanja, omaglicu i omamljenost prije nego što ponovno počnete upravljati vozilima ili raditi sa strojevima.
English: Dispose of it and get a new capsule.
Croatian: Bacite je i uzmite novu kapsulu.
English: What Inbrija is and what it is used for
Croatian: Što je Inbrija i za što se koristi
English: If you cough or stop your dose, start again from the beginning of Step 7 using the same capsule.
Croatian: Ako zakašljete i prekinete uzimati dozu, započnite ponovno od početka 7. koraka koristeći istu kapsulu.
English: You must stop taking these medicines at least 14 days before starting treatment with Inbrija.
Croatian: Te lijekove morate prestati uzimati najmanje 14 dana prije započinjanja liječenja Inbrijom.
English: Important: If you did not hear or feel the capsule “whirl” while inhaling you may need to take a deeper, longer breath.
Croatian: Važno: Ako ne čujete ili ne osjetite „vrtnju“ kapsule dok inhalirate, možda ćete morati uzeti dulji, dublji udah.
English: Start again from the beginning of Step 7 using the same capsule.
Croatian: Započnite ponovno od početka 7. koraka koristeći istu kapsulu.
English: The safety and efficacy of Inbrija in children under 18 years of age have not been established.
Croatian: Pedijatrijska populacija Sigurnost i djelotvornost Inbrije u djece mlađe od 18 godina nisu ustanovljene.
English: Table 2: Baseline features and results of the efficacy endpoints Parameters
Croatian: Tablica 2: Početne karakteristike i rezultati mjera ishoda za djelotvornost Parametri
English: If this applies to you, do not take Inbrija and ask your doctor or pharmacist for advice.
Croatian: Ako se ovo odnosi na Vas, nemojte uzeti Inbriju i upitajte svog liječnika ili ljekarnika za savjet.
English: Abnormal dreams, Insomnia,
Croatian: abnormalni snovi, nesanica,
English: No dose adjustment is required based on smoking status.
Croatian: Nije potrebno prilagođavati dozu na temelju pušačkog statusa.
English: Pulmonary function was assessed by spirometry and carbon monoxide diffusing capacity (DLCO) every 3 months in both groups.
Croatian: Plućna funkcija procijenjena je spirometrijom i mjerenjem difuzijskog kapaciteta pluća za ugljikov monoksid (DLCO) svaka 3 mjeseca u obje skupine.
English: Tricyclic antidepressants
Croatian: Triciklički antidepresivi
English: Inbrija shows dose proportional pharmacokinetics of levodopa from 13 mg to 122 mg.
Croatian: Inbrija pokazuje farmakokinetiku levodope proporcionalnu dozi od 13 mg do 122 mg.
English: Patients should be monitored and supportive care should be provided.
Croatian: Bolesnike se mora nadzirati i osigurati im potporne mjere.
English: Patients should be regularly monitored for the development of impulse control disorders.
Croatian: Bolesnike se mora redovito pratiti zbog razvoja poremećaja kontrole impulsa.
English: After administration of Inbrija the Cmax and AUC0-24 h was 11% to 12% higher for smokers than for non-smokers.
Croatian: Nakon primjene Inbrije Cmax i AUC0-24 h bili su 11% do 12% viši u pušača nego u nepušača.
English: • You do not need to clean the inhaler.
Croatian: • Inhalator ne morate čistiti.
English: Do not stop using Inbrija without checking with your doctor.
Croatian: Nemojte prestati primjenjivati Inbriju a da prethodno to niste provjerili sa svojim liječnikom.
English: EU/1/19/1390/001 EU/1/19/1390/002
Croatian: EU/1/19/1390/002
English: No dose adjustment is required based on gender.
Croatian: Nije potrebno prilagođavati dozu na temelju spola.
English: The whirl means the inhaler is working and you are getting your medicine.
Croatian: To znači da inhalator radi, a Vi primate svoj lijek.
English: Read these instructions before you start using Inbrija.
Croatian: Pročitajte ove upute prije nego što počnete primjenjivati Inbriju Pregled
English: Based on individual assessments of the severity of the intercurrent respiratory infection Inbrija may be continued or discontinued until the respiratory symptoms resolve (see section 4.2).
Croatian: Na temelju individualne procjene težine interkurentne respiratorne infekcije, primjena Inbrije se može nastaviti ili prekinuti dok se respiratorni simptomi ne povuku (vidjeti dio 4.2).
English: The most frequent adverse reactions reported in the Inbrija clinical studies were cough (15.6%), fall (8.7%), upper respiratory tract infection (5.8%), dyskinesia (5.7%) and sputum discoloured (2.8%).
Croatian: Najčešće zabilježene nuspojave u kliničkim ispitivanjima Inbrije bile su kašalj (15,6%), pad (8,7%), infekcija gornjih dišnih putova (5,8%), diskinezija (5,7%) i promijenjena boja iskašljaja (2,8%).
English: Levodopa may cause a false-positive reaction for urinary ketone bodies when a test tape is used for determination of ketonuria.
Croatian: Levodopa može uzrokovati lažno pozitivnu reakciju na ketonska tijela u urinu kada se za određivanje ketonurije koristi test-traka.
English: Any nonselective MAO inhibitors should be discontinued at least 14 days prior to initiating levodopa.
Croatian: Primjenu svih neselektivnih MAO inhibitora treba prekinuti najmanje 14 dana prije početka primjene levodope.
English: The Inbrija inhaler is made of polybutylene terephthalate (PBT), polycarbonate (PC) and polypropylene (PP).
Croatian: Inbrija inhalator načinjen je od polibutilen tereftalata (PBT), polikarbonata (PC) i polipropilena (PP).
English: As you breathe in, you will hear and feel the capsule “whirl” (spin).
Croatian: Dok udišete, čut ćete i osjetiti „vrtnju“ kapsule (da se kapsula okreće).
English: Using more than one dose of Inbrija (2 capsules) to treat the same OFF period may result in CNS disturbances, with an increasing likelihood of cardiovascular disturbance (e.g. hypotension, tachycardia) and more severe psychiatric problems at higher doses.
Croatian: Uzimanje više od jedne doze Inbrije (2 kapsule) za liječenje istog OFFrazdoblja može rezultirati poremećajima SŽS-a, s povećanom vjerojatnosti za kardiovaskularne poremećaje (npr. hipotenziju, tahikardiju) i teže psihijatrijske probleme pri višim dozama.
English: Bronchospasm in patients with lung disease
Croatian: Bronhospazam u bolesnika s plućnom bolesti
English: Elderly No dose adjustment of Inbrija is required for elderly patients (≥65 years).
Croatian: Nije potrebna prilagodba doze Inbrije u starijih bolesnika (≥65 godina).
English: Place the cap to the side.
Croatian: Stavite je na stranu.
English: Parkinson's disease affects your movement and it is treated with a medicine that you take regularly.
Croatian: Parkinsonova bolest je bolest koja utječe na kretnje, a liječi se lijekovima koje redovito uzimate.
English: Levodopa has been associated with somnolence and episodes of sudden sleep onset (see section 4.7).
Croatian: Levodopa se povezuje sa somnolencijom i epizodama iznenadnog nastupa sna (vidjeti dio 4.7).
English: Apomorphine was not allowed as background medicinal product.
Croatian: Primjena apomorfina kao osnovnog lijeka nije bila dopuštena.