FrancophonIA/ELRC3.0 huggingface dataset:
English: With respect to the reproductive toxicity norelgestromin showed foetal toxicity in rabbits, but the safety margin for this effect was sufficiently high.
Slovenian: Pri vplivu na sposobnost razmnoževanja so pri kuncih opazili fetotoksične učinke norelgestromina, varnostni prag za ta učinek pa je bil dovolj visok.
English: Diabetes mellitus, hyperhomocysteinaemia, valvular heart disease and atrial fibrillation, dyslipoproteinaemia, systemic lupus erythematosus.
Slovenian: Sladkorna bolezen, hiperhomocisteinemija, bolezen srčnih zaklopk in atrijska fibrilacija, dislipoproteinemija in sistemski eritematozni lupus.
English: Hypertriglyceridaemia has been associated with an increased risk of developing pancreatitis (inflammation of the pancreas);
Slovenian: Hipertrigliceridemija je povezana s povečanim tveganjem za nastanek pankreatitisa
English: • Put on your first patch during the first 24 hours of your period.
Slovenian: • Prvi obliž namestite v prvih 24 urah menstruacijskega cikla.
English: If a woman has more than one risk factor, it is possible that the increase in risk is greater than the sum of the individual factors - in this case her total risk of VTE should be considered.
Slovenian: Če ima ženska več kot en dejavnik tveganja, se lahko tveganje poveča za več, kot je seštevek posameznih dejavnikov; v tem primeru je treba upoštevati njeno skupno tveganje za VTE.
English: The risk of developing a blood clot in a vein is highest during the first year of taking a combined hormonal contraceptive for the first time.
Slovenian: Tveganje za nastanek krvnega strdka v veni je največje v prvem letu jemanje kombiniranega hormonskega kontraceptiva, ko se ta jemlje prvič.
English: • Abnormal blood sugar or insulin levels
Slovenian: • nenormalne koncentracije sladkorja ali insulina v krvi
English: • if you have Crohn's disease or ulcerative colitis (chronic inflammatory bowel disease);
Slovenian: • če imate Crohnovo bolezen ali ulcerozni kolitis (kronično vnetje črevesa);
English: Blood clots blocking other blood vessels
Slovenian: krvni strdki, ki so zamašili drugo krvno žilo
English: Concomitant use with the medicinal products containing ombitasvir/paritaprevir/ritonavir and dasabuvir, with or without ribavirin may increase the risk of ALT elevations (see sections 4.3 and 4.4).
Slovenian: Sočasna uporaba z zdravili, ki vsebujejo ombitasvir/paritaprevir/ritonavir in dasabuvir, z ribavirinom ali brez njega, lahko zvečajo tveganje za zvečanje ALT (glejte poglavji 4.3 in 4.4).
English: Particularly above 35 years.
Slovenian: Zlasti nad starostjo 35 let.
English: arm and stomach;
Slovenian: žrelo, roko, želodec;
English: A single transdermal patch is applied and worn for one full week (7 days).
Slovenian: Namesti en transdermalni obliž in ga nosi ves teden (7 dni).
English: An increase in frequency or severity of migraine during CHC use (which may be prodromal of a cerebrovascular event) may be a reason for immediate discontinuation.
Slovenian: Če se pri ženskah, ki uporabljajo CHC, pogosteje pojavijo migrene ali so te hujše (kar je lahko prodrom cerebrovaskularnega dogodka), je to lahko razlog za takojšnjo prekinitev jemanja.
English: Driving and using machines You can drive or use machines while using this medicine.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Med uporabo tega zdravila lahko vozite in upravljate stroje.
English: Table 1 below reflects the adverse reactions reported in clinical trials and from post-marketing experience.
Slovenian: V Preglednici 1 so prikazani neželeni učinki, poročani v kliničnih preskušanjih ali v obdobju trženja zdravila.
English: The use of contraceptive steroids may influence the results of certain laboratory tests, including biochemical parameters of liver, thyroid, adrenal and renal function, plasma levels of (carrier) proteins, e.g. corticosteroid-binding globulin and lipid/lipoprotein fractions, parameters of carbohydrate metabolism and parameters of coagulation and fibrinolysis.
Slovenian: Uporaba kontracepcijskih steroidov lahko vpliva na rezultate določenih laboratorijskih testov, vključno z biokemičnimi parametri jeter, ščitnice, nadledvične in ledvične funkcije, plazemske koncentracije (vezavnih) proteinov, npr. globulina, ki veže kortikosteroidne hormone in lipidne/lipoproteinske frakcije, presnove ogljikovih hidratov in koagulacije ter fibrinolize.
English: • Presence or risk of arterial thromboembolism (ATE)
Slovenian: • Prisotnost ali tveganje za arterijsko trombembolijo (ATE)
English: If, during the use of combined hormonal contraceptives in pre-existing hypertension, constantly elevated blood pressure values or a significant increase in blood pressure do not respond adequately to antihypertensive treatment, the combined hormonal contraceptive must be withdrawn.
Slovenian: Če se pri ženskah, ki že imajo hipertenzijo, med uporabo kombiniranih hormonskih kontraceptivov stalno povišane vrednosti krvnega tlaka ali pomembno zvišan krvni tlak ne odzovejo ustrezno na antihipertenzivno zdravljenje, morajo z uporabo kombiniranih hormonskih kontraceptivov prekiniti.
English: Dosage adjustment of the concomitant medicinal product may be necessary.
Slovenian: Morda bo potrebno prilagoditi odmerek sočasno uporabljenega zdravila.
English: A meta-analysis of 54 epidemiological studies reported that there is a slightly increased risk (RR = 1.24) of having breast cancer diagnosed in women who are currently using COCs.
Slovenian: Metaanaliza 54 epidemioloških raziskav kaže, da je pri ženskah, ki jemljejo KPKS, tveganje (RR = 1,24) za raka na prsih nekoliko večje.
English: During clinical trials with patients treated for hepatitis C virus infections (HCV) with the medicinal products containing ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin, transaminase (ALT) elevations higher than 5 times the upper limit of normal (ULN) occurred significantly more frequent in women using ethinyl estradiol-containing medications such as combined hormonal contraceptives (CHCs) (see sections 4.3 and 4.5).
Slovenian: Med kliničnimi preskušanji so se pri bolnikih z okužbo z virusom hepatitisa C, zdravljenih z zdravili, ki vsebujejo kombinacijo ombitasvir/parataprevir/ritonavir in dasabuvir z ribavirinom ali brez njega, zvišale transaminaze (ALT) na več kot 5-kratnik zgornje meje normalnih vrednosti (ULN- upper limit of normal) značilno pogosteje pri ženskah, ki uporabljajo zdravila z etinilestradiolom, kot so npr. kombinirani hormonski kontraceptivi (CHC- combined hormonal contraceptives) (glejte poglavji 4.3 in 4.5).
English: • Undiagnosed abnormal genital bleeding
Slovenian: • nediagnosticirana nenormalna krvavitev iz rodil
English: The excess risk gradually disappears during the course of the 10 years after cessation of COC use.
Slovenian: V desetih letih po prenehanju uporabe KPKS zvečano tveganje postopoma izgine.
English: In women on long-term treatment with enzyme-inducing active substances, another reliable, non-hormonal, method of contraception is recommended.
Slovenian: Pri ženskah, ki se daljši čas zdravijo z zdravilnimi učinkovinami, ki inducirajo encime, moramo razmisliti o drugi, zanesljivi nehormonski kontracepcijski metodi.
English: If you do not get your period during the EVRA patch-free week (Week 4), you should still use a new patch on your usual “Patch Change Day”.
Slovenian: Če v tednu, ko obliža EVRA ne uporabljate (premor v 4. tednu), ne dobite menstruacije, morate vseeno uporabiti nov obliž na vaš običajni dan zamenjave.
English: • if you have hepatitis C and are taking the medicinal products containing ombitasvir/paritaprevir/ritonavir and dasabuvir (see also in section “Other medicines and EVRA”).
Slovenian: • če imate okužbo z virusom hepatitisa C in jemljete zdravila, ki vsebujejo ombitasvir/pritaprevir/ritonavir in dasabuvir (glejte tudi poglavje “Druga zdravila in obliž EVRA”)
English: EVRA should be applied to clean, dry, hairless, intact healthy skin on the buttock, abdomen, upper outer arm or upper torso, in a place where it will not be rubbed by tight clothing.
Slovenian: Obliž EVRA moramo namestiti na čisto, suho, neporaščeno, nepoškodovano zdravo kožo zadnjice, trebuha, zunanje strani nadlahti ali zgornjega dela trupa, in sicer na takšno mesto, da se ob obliž ne bodo drgnila tesna oblačila.
English: • Mood problems such as depression, change in mood or mood swings, anxiety, crying
Slovenian: • motnje razpoloženja kot so depresija, spremembe ali nihanje razpoloženja, tesnoba, jokavost
English: • Allergic reaction, hives
Slovenian: • alergijske reakcije, koprivnica
English: • Swelling in the arms, hands, legs or feet.
Slovenian: • otečene roke, dlani, noge ali stopala
English: Studies conducted to examine the dermal effect of EVRA indicate this system has no potential to produce sensitisation and results in only mild irritation when applied to rabbits skin.
Slovenian: Raziskave, v katerih so proučevali vpliv obliža EVRA na kožo, kažejo, da ne povzroča senzibilizacije, ampak le blago draženje, če ga namestimo na kožo kuncev.
English: Symptoms of a cerebrovascular accident can include: - sudden numbness or weakness of the face, arm or leg, especially on one side of the body; - sudden trouble walking, dizziness, loss of balance or coordination; - sudden confusion, trouble speaking or understanding; - sudden trouble seeing in one or both eyes; - sudden, severe or prolonged headache with no known cause; - loss of consciousness or fainting with or without seizure.
Slovenian: Simptomi cerebrovaskularnega dogodka lahko vključujejo: - nenadno odrevenelost ali šibkost obraza, rok ali nog, zlasti po eni strani telesa; - nenadne težave s hojo, omotičnost, izgubo ravnotežja ali koordinacije; - nenadna zmedenost, težave z govorjenjem ali razumevanjem; - nenadne težave z vidom na enem ali obeh očesih; - nenaden, hud ali podaljšan glavobol brez znanega razloga; - izguba zavesti ali omedlevica z napadi krčev ali brez njih.
English: • Known hereditary or acquired predisposition for venous thromboembolism, such as APC-resistance, (including Factor V Leiden), antithrombin-III-deficiency, protein C deficiency, protein S deficiency;
Slovenian: • Znana dedna ali pridobljena nagnjenost k venski trombemboliji, kot je rezistenca za aktivirani protein C (APC, activated protein C resistance), (vključno s faktorjem V Leiden), pomanjkanje antitrombina-III, pomanjkanje proteina C, pomanjkanje proteina S.
English: Effects of other medicinal products on EVRA
Slovenian: Učinek drugih zdravil na obliž EVRA
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity and carcinogenic potential.
Slovenian: Neklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih, genotoksičnosti in kancerogenega potenciala ne kažejo posebnega tveganja za človeka.
English: • if you notice possible signs of a blood clot that may mean you are suffering from a blood clot in the leg (i.e. deep vein thrombosis), a blood clot in the lung (i.e. pulmonary embolism), a heart attack or a stroke (see ‘Blood clot [thrombosis] section below).
Slovenian: • če opazite možne znake krvnega strdka, ki lahko pomenijo, da imate krvni strdek v nogi (tj. globoko vensko trombozo), krvni strdek v pljučih (tj. pljučno embolijo), srčni infarkt ali možgansko kap (glejte spodnje poglavje"Krvni strdek [tromboza])".
English: EVRA contains two types of sex hormones, a progestogen called norelgestromin and an oestrogen called ethinyl estradiol.
Slovenian: Obliž EVRA vsebuje dva spolna hormona: progestogen, imenovan norelgestromin in estrogen, imenovan etinilestradiol.
English: However, if EVRA has not been taken according to these directions prior to the first missed withdrawal bleed or if two withdrawal bleeds are missed, pregnancy must be ruled out before EVRA use is continued.
Slovenian: Če pa pred prvim izostankom prekinitvene krvavitve ženska obližev EVRA ni uporabljala v skladu s temi navodili ali če sta izostali dve prekinitveni krvavitvi, moramo pred nadaljnjo uporabo obližev EVRA izključiti nosečnost.
English: Note: The prescribing information of concomitant medicinal products should be consulted to identify potential interactions.
Slovenian: Opomba: preberite navodila za predpisovanje drugih sočasno uporabljenih zdravil, da ugotovite možne interakcije.
English: Body weight equal or greater than 90 kg Contraceptive efficacy may be decreased in women weighing equal or greater than 90 kg.
Slovenian: Telesna masa 90 kg ali več Pri ženskah s telesno maso 90 kg ali več se učinkovitost kontracepcije lahko zmanjša.
English: - Out of 10,000 women who are not using any combined hormonal contraceptive and are not pregnant, about 2 will develop a blood clot in a year.
Slovenian: • Na 10.000 žensk, ki ne uporabljajo nobenega kombiniranega hormonskega kontraceptiva in niso noseče, se bo krvni strdek razvil pri približno 2 ženskah na leto.
English: The overall risk of a blood clot in the leg or lung (DVT or PE) with EVRA is small.
Slovenian: Splošno tveganje krvnega strdka v nogah ali pljučih (globoka venska tromboza ali pljučna embolija) z zdravilom EVRA je majhno.
English: • if you have sickle cell anaemia (an inherited disease of the red blood cells);
Slovenian: • če imate srpastocelično anemijo (dedno bolezen rdečih krvnih celic);
English: Using a combined hormonal contraceptive such as EVRA increases your risk of developing a blood clot compared with not using one.
Slovenian: Z uporabo kombiniranega hormonskega kontraceptiva, kot je zdravilo EVRA, se vaše tveganje za razvoj krvnega strdka v primerjavi z ženskami, ki ga ne uporabljajo, poveča.
English: What can happen if a blood clot forms in an artery?
Slovenian: Kaj se lahko zgodi, če v arteriji nastane krvni strdek?
English: Risk of arterial thromboembolism (ATE)
Slovenian: Tveganje arterijske trombembolije (ATE)
English: • Fluid retention in legs
Slovenian: • zadrževanje tekočine v nogah
English: • Known hereditary or acquired predisposition for arterial thromboembolism, such as hyperhomocysteinaemia and antiphospholipid-antibodies (anticardiolipin-antibodies, lupus anticoagulant);
Slovenian: • Znana dedna ali pridobljena nagnjenost k arterijski trombemboliji, kot sta hiperhomocisteinemija in antifosfolipidna protitelesa (antikardiolipinska protitelesa, lupusni antikoagulant).
English: After 7 days of not wearing a patch, apply a new patch and restart the cycle using this as Day 1.
Slovenian: Po 7 dnevnem premoru namestite nov obliž in začnite z novim ciklom na ta dan (dan 1).
English: At the end of the cycle (Week Four/Day 22) - If the EVRA transdermal patch is not removed at the beginning of Week 4 (Day 22), it should be removed as soon as possible.
Slovenian: dan) - Če ženska transdermalnega obliža EVRA ne odstrani na začetku 4. tedna (22. dan), ga mora odstraniti takoj, ko je to mogoče.
English: The majority of recent studies also do not indicate a teratogenic effect when combined oral contraceptives are used inadvertently during early pregnancy.
Slovenian: Večina sodobnih raziskav tudi ni dokazala teratogenega učinka kombiniranih peroralnih kontraceptivov, ki jih ženska nenamerno uporablja na začetku nosečnosti.
English: Every carton has 3, 9 or 18 EVRA transdermal patches in individual foil-lined sachets.
Slovenian: Vsaka škatla vsebuje 3, 9 ali 18 transdermalnih obližev EVRA, od katerih je vsak posebej zapakiran v blazinico, prevlečeno s folijo.
English: Combined hormonal contraceptive use may be resumed if normotensive values can be achieved with antihypertensive therapy.
Slovenian: Z uporabo kombiniranih hormonskih kontraceptivov lahko nadaljujejo, če z antihipertenzivnim zdravljenjem lahko dosežemo normalne vrednosti krvnega tlaka.
English: If transdermal patch use results in uncomfortable irritation, a new transdermal patch may be applied to a new location until the next Change Day.
Slovenian: Če uporaba transdermalnega obliža povzroča neprijetno draženje, lahko ženska do naslednjega dneva zamenjave nov transdermalni obliž namesti na drugo mesto.
English: Positive family history (arterial thromboembolism ever in a sibling or parent at relatively early age e.g. below 50)
Slovenian: Pozitivna družinska anamneza (arterijska trombembolija kadar koli pri sorojencu ali staršu v sorazmerno zgodnji starosti, npr. pred 50 letom).
English: • if you have (or have ever had) a blood clot in a blood vessel of your legs (deep vein thrombosis,
Slovenian: • če imate (ali ste kdaj imeli) krvni strdek v krvni žili nog (globoka venska tromboza), pljučih
English: The absorption of norelgestromin and ethinyl estradiol following application of EVRA was studied under conditions encountered in a health club (sauna, whirlpool, treadmill and other aerobic exercise) and in a cold water bath.
Slovenian: Po namestitvi obliža EVRA so absorpcijo norelgestromina in etinilestradiola proučevali v pogojih, katerim so ženske izpostavljene pri telesnih aktivnostih (savna, jacuzzi, hoja po tekočem traku in druge aerobne vaje) ter pri kopelih s hladno vodo.
English: Blood glucose decreased*† Blood glucose abnormal*†
Slovenian: redki znižana koncentracija glukoze v krvi*† nenormalna koncentracija glukoze v krvi *†
English: • as you get older (particularly above about 35 years);
Slovenian: • s starostjo (zlasti nad 35 leti);
English: EVRA should not be placed on the breasts or on skin that is red, irritated or cut.
Slovenian: Obliža EVRA ne smemo namestiti na prsi ali na pordelo, razdraženo ali poškodovano kožo.
English: The use of any combined hormonal contraceptive (CHC) increases the risk of venous thromboembolism (VTE) compared with no use.
Slovenian: Z uporabo katerega koli kombiniranega hormonskega kontraceptiva (CHC, combined hormonal contraceptive) je tveganje za pojav venske trombembolije (VTE) večje kot pri neuporabi.
English: In multiple-dose studies, serum concentrations and AUC for norelgestromin and EE were found to increase only slightly over time when compared to week 1 cycle 1.
Slovenian: V raziskavah, v katerih so ženske prejemale več odmerkov, so ugotovili, da serumske koncentracije norelgestromina in etinilestradiola ter površina pod krivuljo (AUC) sčasoma le rahlo narastejo v primerjavi s 1. tednom 1. cikla.
English: When you should not use EVRA
Slovenian: Kdaj obliža EVRA ne smete uporabljati
English: - The risk of having a blood clot will vary according to your personal medical history (see “Factors that increase your risk of a blood clot” below).
Slovenian: • Tveganje za nastanek krvnega strdka se razlikuje glede na vašo osebno anamnezo (glejte spodnje poglavje "Dejavniki, ki povečujejo vaše tveganje za krvni strdek").
English: • You may start this medicine on the first day of your next period.
Slovenian: • To zdravilo lahko začnete uporabljati prvi dan menstruacije.
English: Inter-subject variability (%CV) for the PK parameters following delivery from EVRA was higher relative to the variability determined from the oral contraceptive.
Slovenian: Variabilnost farmakokinetičnih parametrov med posameznicami (% CV), je bila višja pri obližih EVRA kot tista, določena pri peroralnem kontraceptivu.
English: Using your fingers, open the foil sachet.
Slovenian: S prsti odprite blazinico, prevlečeno s folijo.
English: It has not been shown that a transdermal patch like EVRA is safer than a combined birth control pill taken by mouth.
Slovenian: Ni bilo dokazano, da je uporaba transdermalnih obližev, kot je zdravilo EVRA varnejša od kontracepcijskih tablet, ki jih pogoltnete.
English: EVRA is contraindicated if a woman has one serious or multiple risk factors for ATE that puts her at high risk of arterial thrombosis (see section 4.3).
Slovenian: Zdravilo EVRA je kontraindicirano, če ima ženska enega resnega ali več dejavnikov tveganja za ATE, ki žensko izpostavijo visokemu tveganju za arterijsko trombozo (glejte poglavje 4.3).
English: Your doctor will discuss with you what other form of birth control would be more appropriate.
Slovenian: Vaš zdravnik se bo z vami pogovoril o drugih, bolj ustreznih načinih preprečevanja neželene nosečnosti.
English: The breast cancers diagnosed in ever-users tend to be less advanced clinically than the cancers diagnosed in never-users.
Slovenian: Rak na prsih, diagnosticiran pri ženskah, ki stalno jemljejo KPKS, je klinično manj napredoval kot rak, diagnosticiran pri ženskah, ki KPKS niso nikoli uporabljale.
English: • Concomitant use with the medicinal products containing ombitasvir/paritaprevir/ritonavir and dasabuvir (see sections 4.4 and 4.5).
Slovenian: • sočasna uporaba z zdravili, ki vsebujejo ombitasvir/paritaprevir/ritonavir in dasabivir (glejte poglavji 4.4 in 4.5)
English: Arterial thromboembolism (Acute) myocardial infarction*†
Slovenian: Arterijski trombembolizem (akutni) miokardni infarkt*†
English: • Changes in menstrual bleeding pattern, uterine cramps, painful periods, vaginal discharge
Slovenian: • spremembe vzorca menstrualnih krvavitev, maternični krči, boleče menstruacije, izcedek iz nožnice
English: Data for combination of norgestimate (precursor of norelgestromin) with ethinyl estradiol indicate for female animals a decrease in fertility and implantation efficiency (rat), an increase in foetal resorption (rat, rabbit) and, with high dosages, a decrease in viability and fertility of female offspring (rat).
Slovenian: Podatki za kombinacijo norgestimata (prekurzor norelgestromina) in etinilestradiola kažejo, da sta se pri samicah zmanjšali plodnost in implantacijska učinkovitost (podgane), povečala se je resorpcija ploda (podgane in kunci), pri velikih odmerkih pa sta se pri potomcih ženskega spola (podgane) zmanjšali sposobnost preživetja in plodnost.
English: If concomitant medicinal product administration extends beyond the end of the three-week patch period, the next transdermal patch should be applied without the usual transdermal patch-free interval.
Slovenian: Če se uporaba drugega zdravila med sočasno uporabo transdermalnega obliža podaljša čez tri tedne, se mora naslednji transdermalni obliž namestiti brez običajnega premora.
English: Substances with variable effects on the clearance of CHCs When co-administered with CHCs, many combinations of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors, including combinations with HCV inhibitors can increase or decrease plasma concentrations of estrogen or progestins.
Slovenian: Med sočasno uporabo s CHC lahko številne kombinacije zaviralcev proteaz HIV in nenukleozidnih zaviralcev reverzne transkriptaze, vključno s kombinacijami zaviralcev HCV zvečajo ali zmanjšajo plazemske koncentracije estrogenov in progestinov.
English: Substances increasing the clearance of CHCs (diminished efficacy of CHCs by enzyme-induction),e.g.: Barbiturates, bosentan, carbamazepine, phenytoin, primidone, rifampicin, modafinil and HIV medication ritonavir, nevirapine and efavirenz and possibly also felbamate, griseofulvin, oxcarbazepine, topiramate and products containing the herbal remedy St. John's Wort (hypericum perforatum).
Slovenian: Učinkovine, ki zvečajo očistek CHC (zmanjšana učinkovitost CHC z indukcijo encimov) kot so: barbiturati, bosentan, karbamazepin, fenitoin, primidon, rifampicin, modafinil in zdravila za zdravljenje HIV: ritonavir, nevirapin in efavirenz; verjetno tudi felbamat, grizeofulvin, okskarbazepin, topiramat in zeliščni pripravki s šentjanževko (Hypericum perforatum).
English: Recurrence of cholestatic-related pruritus, which occurred during a previous pregnancy or previous use of sex steroids necessitates the discontinuation of combined hormonal contraceptives.
Slovenian: Če se s holestazo povezan pruritus, ki se je pojavil že med prejšnjo nosečnostjo ali med predhodno uporabo kontracepcijskih steroidnih hormonov, ponovno pojavi, mora ženska z jemanjem kombiniranih hormonskih kontraceptivov prenehati.
English: However, if intercourse has already occurred, pregnancy should be excluded before the actual start of EVRA or the woman has to wait for her first menstrual period.
Slovenian: Če pa je že imela spolni odnos, moramo pred začetkom uporabe obliža EVRA izključiti nosečnost ali pa počakati do naslednje menstruacije.