FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients should be clinically evaluated after two years of treatment and longer-term treatment should be decided on an individual basis by the treating physician.
Croatian: Nakon dvije godine liječenja treba izvršiti kliničku procjenu učinka liječenja bolesnika, a odluku o produžetku liječenja, na temelju individualnog pristupa svakom pojedinom bolesniku treba donijeti liječnik koji ih je do tog trenutka liječio.
English: The AVONEX PEN contains a pre-filled syringe of AVONEX and must be stored in the refrigerator.
Croatian: AVONEX PEN sadrži napunjenu štrcaljku AVONEXA i mora se čuvati u hladnjaku.
English: Adults: The recommended dosage for the treatment of relapsing MS is 30 micrograms (0.5 ml solution), administered by intramuscular (IM) injection once a week (see section 6.6).
Croatian: Odrasli: Preporučeno doziranje za liječenje relapsne MS-e je 30 mikrograma (0,5 ml otopine), koje se daje jednom tjedno intramuskularnom (i.m.) injekcijom (vidjeti dio 6.6).
English: Store the AVONEX PEN in the inner carton in order to protect from light (see section 6.5).
Croatian: AVONEX PEN treba čuvati u unutarnjoj kutiji radi zaštite od svjetlosti (vidjeti dio 6.5).
English: What AVONEX PEN looks like and contents of the pack
Croatian: Kako AVONEX izgleda i sadržaj pakiranja
English: 3A syncope episode may occur after AVONEX injection, it is normally a single episode that usually appears at the beginning of the treatment and does not recur with subsequent injections.
Croatian: 3Epizoda sinkope se može pojaviti nakon injekcije AVONEXA i to obično samo jedanput na početku liječenja, dok se nakon idućih injiciranja više ne ponavlja.
English: • Gently, turn the needle clockwise until it is firmly attached, otherwise the needle may leak.
Croatian: • Pažljivo okrenite iglu u smjeru kazaljke na satu sve dok nije dobro učvršćena jer u suprotnom bi igla mogla propuštati tekućinu.
English: Make sure the cap is intact and has not been opened.
Croatian: Provjerite je li zatvarač na svom mjestu i nije li već otvaran.
English: If you miss an injection
Croatian: Ako ste propustili injicirati injekciju
English: - Feeling faint: Your first injection of Avonex may be given by your doctor.
Croatian: Nuspojave injekcije - Osjećaj nesvjestice: Prvu injekciju Avonexa bi Vam trebao dati Vaš liječnik.
English: UAB "JOHNSON & JOHNSON"
Croatian: Lietuva UAB "JOHNSON & JOHNSON"
English: The active substance is: Interferon beta-1a 30 micrograms/0.5 ml
Croatian: Djelatna tvar je: interferon beta-1a 30 mikrograma/0,5 ml
English: You can inject Avonex yourself without the help of your doctor, if they have trained you to do this.
Croatian: Injekciju Avonexa možete si dati samostalno, bez pomoći liječnika ako ste podučeni kako to raditi.
English: 4 Check the injector shield is extended correctly
Croatian: 4 Provjerite je li štitnik injektora ispravno produžen
English: You may not get the full dose if it leaks.
Croatian: Ukoliko propušta, možda nećete dobiti punu dozu.
English: Important information about some of the ingredients of Avonex
Croatian: Važne informacije o nekim sastojcima AVONEXA
English: Similar reproductive dose-related effects have also been observed with other forms of alpha and beta interferons.
Croatian: Do sličnih, o dozi ovisnih učinaka na reproduktivni sustav dolazilo je i prilikom davanja drugih oblika alfa i beta interferona.
English: Avonex Pen - after injection (prepared for disposal)
Croatian: Avonex Pen - nakon injiciranja (spreman za odbaciti)
English: Avonex can be used during breast-feeding.
Croatian: Avonex se može koristiti tijekom dojenja.
English: Contents of the pack and other information What AVONEX contains
Croatian: Sadržaj pakiranja i druge informacije Što AVONEX sadrži
English: Patients exhibiting depression should be monitored closely during therapy and treated appropriately.
Croatian: Bolesnike koji pokazuju simptome depresije tijekom liječenja treba pojačano nadzirati i primjereno liječiti.
English: Patients with myelosuppression may require more intensive monitoring of complete blood cell counts, with differential and platelet counts.
Croatian: Bolesnici s mijelosupresijom zahtijevaju još temeljitiju kontrolu ukupnog broja krvnih stanica s diferencijalnom krvnom slikom i brojem trombocita.
English: Pull the needle out
Croatian: Izvucite iglu
English: Patients with cardiac disease, such as angina, congestive heart failure or arrhythmia, should be closely monitored for worsening of their clinical condition during treatment with AVONEX.
Croatian: Tijekom liječenja AVONEXOM kod bolesnika sa srčanim bolestima kao što su angina, kongestivno zatajenje srca ili aritmija, treba pažljivo nadzirati pogoršanje njihovog kliničkog stanja.
English: - Blood clots in the small blood vessels that can affect your kidneys (thrombotic thrombocytopenic purpura or haemolytic uremic syndrome).
Croatian: - Krvni ugrušci u malim krvnim žilama koji mogu utjecati na Vaše bubrege (trombotička trombocitopenička purpura ili hemolitički uremički sindrom).
English: It may make you feel faint.
Croatian: Moguće je da osjetite nesvjesticu.
English: 10 seconds.
Croatian: sekundi.
English: • Peel off the foil from the base of the needle cover.
Croatian: • Maknite foliju s baze pokrova za iglu.
English: The right hand pages have the information you will need to use Avonex Pen properly.
Croatian: Na stranicama s desne strane nalaze se informacije koje ćete trebati za ispravnu primjenu Avonex
English: Caution should be exercised when AVONEX is administered in combination with medicinal products that have a narrow therapeutic index and are largely dependent on the hepatic cytochrome P450 system for clearance, e.g. some classes of antiepileptics and antidepressants.
Croatian: S osobitom pozornošću treba davati AVONEX u kombinaciji s lijekovima koji imaju uzak terapijski indeks i čije je uklanjanje jako ovisno o jetrenom enzimatskom P450 sustavu, primjerice neke skupine antiepileptika i antidepresiva.
English: It may be possible for your doctor to prescribe you a shorter and thinner needle, depending on your body type.
Croatian: Ovisno o tipu vašeg tijela, liječnik Vam može propisati manju i tanju iglu.
English: ┼ Class label for interferon products, see below Pulmonary arterial hypertension.
Croatian: ┼Značajka klase lijekova koji sadrže interferon, vidjeti niže Plućna arterijska hipertenzija.
English: Do not use Avonex pen if you notice:
Croatian: Nemojte primijeniti Avonex Pen ako primijetite:
English: Patients should be monitored for signs of hepatic injury and caution exercised when interferons are used concomitantly with other medicinal products associated with hepatic injury.
Croatian: Kod bolesnika treba pratiti znakove oštećenja jetre i uz veliki oprez ukoliko uzimaju interferone istodobno s drugim lijekovima koji su povezani s oštećenjem jetre.
English: At very high doses, anovulatory and abortifacient effects in test animals were observed.
Croatian: Pri vrlo visokim dozama, u pokusnih životinja primijećeni su anovulatorni i abortivni učinci.
English: Check the expiry date on the Avonex Pen label.
Croatian: Provjerite rok valjanosti na naljepnici Avonex Pena.
English: You can inject Avonex yourself using the Avonex Pen without the help of your doctor, if they have trained you to do this.
Croatian: Injekciju Avonexa možete si dati samostalno koristeći Avonex Pen, bez pomoći liječnika ako ste podučeni kako to raditi.
English: What AVONEX is and what it is used for What you need to know before you use AVONEX How to use AVONEX
Croatian: Što je AVONEX i za što se koristi Što morate znati prije nego počnete primjenjivati AVONEX Kako primjenjivati AVONEX Moguće nuspojave
English: A double-blind randomised dose comparison study of 802 relapsing MS patients (AVONEX 30 micrograms n=402, AVONEX 60 micrograms n=400) has shown no statistically significant differences or trends between the 30 micrograms and the 60 micrograms doses of AVONEX in clinical and general MRI parameters.
Croatian: Dvostruko slijepo ispitivanje uspoređivanja randomiziranih doza na 802 bolesnika s relapsirajućom MS-om (AVONEX, 30 mikrograma n=402, AVONEX, 60 mikrograma n=400) nije pokazala statistički značajne razlike između doza Avonexa od 30 mikrograma i 60 mikrograma u kliničkim i općim MRI parametrima.
English: If you have trouble handling the Avonex Pen, ask your doctor who may be able to help.
Croatian: Ako imate problema pri rukovanju Avonex Penom, zatražite od svog liječnika da Vam pomogne.
English: These interferons have overlapping but clearly distinguishable biological activities.
Croatian: Navedeni interferoni imaju neke sličnosti, ali biološko djelovanje im je jasno razdvojeno.
English: AVONEX PEN is a pre-filled pen, intended for single use, and should only be used following adequate training.
Croatian: AVONEX PEN jest napunjena brizgalica, namijenjena za jednokratnu uporabu, koja se smije koristiti samo nakon odgovarajuće obuke.
English: Do NOT use Avonex if you notice:
Croatian: NEMOJTE primijeniti Avonex ako primijetite:
English: Central nervous system-related adverse reactions may have a minor influence on the ability to drive and use machines in susceptible patients (see section 4.8).
Croatian: Nuspojave središnjeg živčanog sustava mogu imati manji utjecaj na sposobnost podložnih bolesnika na upravljanje vozilima i rada sa strojevima (vidjeti dio 4.8).
English: Avonex Pen is now ready to inject.
Croatian: Avonex Pen je sada spreman za injiciranje.
English: (Notes information)
Croatian: (Napomene)
English: Contents of the pack and other information What AVONEX PEN contains
Croatian: Sadržaj pakiranja i druge informacije Što AVONEX PEN sadrži
English: AVONEX is indicated for the treatment of
Croatian: AVONEX je indiciran za liječenje
English: numbness in the face, arms or legs - Acute or chronic pain, bladder and bowel problems, sexual problems and problems seeing things - Difficulty in thinking and concentrating, depression.
Croatian: - Akutnu ili kroničnu bol, probleme s mjehurom ili crijevima, seksualne probleme i poteškoće s vidom - Poteškoće u razmišljanju i koncentraciji, depresiju.
English: The solution for injection can be observed through an oval medication display window on the AVONEX PEN.
Croatian: Otopina za injekciju može se vidjeti kroz ovalni prozorčić za prikaz lijeka koji se nalazi na AVONEX PENU.
English: Do not use AVONEX:
Croatian: Nemojte primjenjivati AVONEX:
English: avonex
Croatian: AVONEXOM.
English: If any of the effects trouble you, talk to your doctor.
Croatian: Ako vas muči bilo koja od nuspojava, razgovarajte sa svojim liječnikom.
English: How AVONEX works
Croatian: Kako AVONEX djeluje
English: unexplained bruising or bleeding.
Croatian: ponovljene infekcije, neobjašnjivo nastajanje modrica ili krvarenja.
English: The Avostartclip attaches to the syringe and enables you to gradually increase your dose of Avonex when you first start treatment.
Croatian: Avostartclip se pričvrsti na štrcaljku i omogućuje Vam da postupno povećavate dozu Avonexa kad prvi put započinjete s liječenjem.
English: AVONEX should be discontinued in patients who develop progressive MS.
Croatian: AVONEX treba prestati davati bolesnicima u kojih se razvio progresivni oblik MS-e.
English: The needle must go all the way in.
Croatian: Igla mora potpuno ući u tkivo.
English: Natural interferon beta and AVONEX (interferon beta-1a) are glycosylated and have a single N-linked complex carbohydrate moiety.
Croatian: Prirodni interferon beta i AVONEX (interferon beta-1a) su glikozilirani, odnosno, preko dušika imaju vezan ugljikohidratni kompleks.
English: Swelling, particularly in the ankles and eyelids, and weight gain.
Croatian: - Oticanje, posebno gležnjeva i očnih kapaka, i povećanje tjelesne težine.
English: If there is any blood at the site, wipe it off.
Croatian: Ako primijetite krv na mjestu injiciranja, obrišite ju.
English: • The plastic needle cover will “pop” off.
Croatian: • Plastični pokrov igle će iskočiti.
English: Your doctor will tell you how long you need to keep using Avonex.
Croatian: Liječnik će Vam reći koliko dugo ćete trebati primjenjivati Avonex.
English: Blood and lymphatic system disorders not known rare pancytopenia, thrombocytopenia thrombotic microangiopathy including thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome*
Croatian: Poremećaji krvi i limfnog sustava nepoznato rijetko pancitopenija, trombocitopenija trombotička mikroangiopatija uključujući trombotičku trombocitopeničku purpuru/hemolitički uremički sindrom*
English: The highest incidence of adverse reactions associated with AVONEX therapy is related to flu-like symptoms.
Croatian: Nuspojave s najvećom incidencijom povezane s terapijom AVONEXOM su simptomi slični gripi.
English: - The pre-filled syringe is broken.
Croatian: Napunjena štrcaljka je slomljena.
English: Avonex Pen - prepared for injection
Croatian: Avonex Pen - pripremljen za injiciranje
English: Check the liquid in the syringe
Croatian: Pregledajte otopinu u štrcaljki
English: No case of overdose has been reported.
Croatian: Ne postoje izvješća vezana uz predoziranje lijekom.
English: Subcutaneous administration cannot be substituted for intramuscular administration.
Croatian: Supkutana primjena nikako ne može zamijeniti intramuskularnu primjenu.
English: Do not shake Avonex Pen.
Croatian: Nemojte tresti Avonex Pen.
English: Patient-time is the sum of individual units of time that the patient in the study has been exposed to AVONEX before experiencing the adverse reaction.
Croatian: Bolesnik-vrijeme je zbroj individualnih razdoblja za vrijeme kod kojih je bolesnik tijekom ispitivanja bio izložen AVONEXU prije nego što su nastupile nuspojave.
English: 2 Fit the needle
Croatian: 2 Pričvrstite iglu
English: The most commonly reported flu-like symptoms are myalgia, fever, chills, sweating, asthenia, headache and nausea.
Croatian: Najčešće prijavljeni simptomi slični gripi su mialgija, vrućica, zimica, znojenje, astenija, glavobolja i mučnina.
English: The calculated bioavailability is greater without such adjustments.
Croatian: Bez takvih usklađivanja izračunata bioraspoloživost je veća.
English: Avonex Pen contains a pre-filled syringe of Avonex.
Croatian: Avonex Pen sadrži napunjenu štrcaljku Avonexa.
English: Pack contents - Avonex Pen, needle and Avonex Pen cover
Croatian: Avonex Pen (za jednokratnu uporabu) Sadržaj pakiranja - Avonex Pen, igla i Avonex Pen zatvarač
English: 2 Place Avonex Pen on the skin
Croatian: 2 Stavite Avonex Pen na kožu
English: Store in a refrigerator (2°C - 8°C).
Croatian: Čuvati u hladnjaku (između 2 °C - 8 °C).
English: What AVONEX is
Croatian: Što je AVONEX
English: Avostartclips can be attached onto the syringe enabling a reduced dose of Avonex to be injected at the start of treatment.
Croatian: Avostartclip se može pričvrstiti na štrcaljku čime se omogućava primjena smanjene doze Avonexa na početku liječenja.
English: Symptoms you might notice are tiredness, repeated infection,
Croatian: Simptomi koje biste mogli primijetiti su umor,
English: There are more details on how to inject using the Avonex Pen: In the fold-out section at the back of this leaflet.
Croatian: Postoji više detalja kako injicirati koristeći Avonex Pen: nalaze se u dijelu koji se može rastvoriti na kraju ove upute.
English: In a box of Avonex there are four or twelve ready to use (pre-filled) syringes, each with 0.5 ml of a clear, colourless liquid inside.
Croatian: U kutiji Avonexa nalaze se četiri ili dvanaest napunjenih štrcaljki spremnih za primjenu, a svaka sadrži 0,5 ml bistre, bezbojne tekućine.
English: The recommended intramuscular injection site using the AVONEX PEN is the upper, outer thigh muscle.
Croatian: Preporučeno mjesto za primjenu intramuskularne injekcije AVONEX PENA jest gornji, vanjski dio bedrenog mišića.
English: Avonex Pen is used to inject Avonex.
Croatian: Avonex Pen se koristi za davanje injekcije Avonexa.
English: For administration of AVONEX via the AVONEX PEN, the instructions in the package leaflet should be followed.
Croatian: Za primjenu AVONEXA koristeći AVONEX PEN treba slijediti naputke sadržane u Uputi o lijeku.
English: Furthermore, for the time-being there is no well established definition of a high risk patient although a more conservative approach is to accept at least nine T2 hyperintense lesions on the initial scan and at least one new T2 or one new Gd-enhancing lesion on a follow-up scan taken at least three months after the initial scan.
Croatian: Trenutno nema dobro utvrđene definicije visokorizičnog bolesnika, premda konzervativni pristup prihvaća kao takvog onog s najmanje devet T2 hiper-intenzivnih lezija na početnom skenu i koji na sljedećem skenu, učinjenom najmanje tri mjeseca nakon početnog skena, ima najmanje jednu novu T2 ili jednu novu Gd-pozitivnu leziju.
English: - Kidney problems including scarring that may reduce your kidney function If you get some or all of these symptoms:
Croatian: - Problemi s bubrezima uključujući ožiljke koji mogu smanjiti funkciju Vaših bubrega Ako Vam se pojave neki ili svi ovi simptomi: - Pjenušava mokraća
English: - If you are having a blood test. Avonex may interfere with the results.
Croatian: ako radite krvne pretrage jer Avonex može utjecati na rezultate.
English: If this happens to you, or if you get any other side effects that could affect your ability, do not drive or use machines.
Croatian: Vama ili ako primijetite da je Vaša sposobnost upravljanja narušena zbog pojave nekih drugih nuspojava, nemojte upravljati vozilima ili raditi sa strojevima.
English: • Avonex is injected into a muscle, for example, the upper thigh muscle.
Croatian: • Avonex se injicira u mišić, na primjer u gornji, vanjski dio bedrenog mišića.
English: 1 What AVONEX is and what it is used for
Croatian: 1 Što je AVONEX i za što se koristi
English: Press the needle onto the syringe.
Croatian: Pritisnite iglu za injekciju na štrcaljku.
English: A small rectangular area will be visible next to the oval display window.
Croatian: Bit će vidljiv mali pravokutni prozorčić pored ovalnog prozorčića za prikaz lijeka.
English: Cardiac disorders not known cardiomyopathy, congestive heart failure (see section 4.4), palpitations, arrhythmia, tachycardia
Croatian: Srčani poremećaji nepoznato kardiomiopatija, kongestivno zatajenje srca (vidjeti dio 4.4), palpitacije, aritmija,
English: Flu-like symptoms
Croatian: Simptomi slični gripi
English: Therefore, in addition to those laboratory tests normally required for monitoring patients with MS, complete and differential white blood cell counts, platelet counts, and blood chemistry, including liver function tests, are recommended during AVONEX therapy.
Croatian: Stoga se, uz uobičajene laboratorijske testove koji se redovno izvode prilikom kontrole bolesnika s MS-om, za bolesnike koji dobivaju AVONEX preporučuje određivanje ukupnog i pojedinačnog broja bijelih krvnih stanica, broja trombocita, biokemijske pretrage krvi, uključujući testove za kontrolu funkcije jetre.
English: Flu-like symptoms tend to be most prominent at the initiation of therapy and decrease in frequency with continued treatment.
Croatian: Simptomi slični gripi su najizraženiji na početku terapije i učestalost im opada nastavkom liječenja.
English: Make the injection Insert the injection needle with a quick dart-like thrust at right angles to the skin, into the muscle.
Croatian: Brzim potezom ubodite iglu kao strelicu pod pravim kutom kroz kožu u mišić.
English: Injection of Avonex into the buttocks is not recommended.
Croatian: Ne preporučuje se injicirati Avonex u stražnjicu.
English: In a post-hoc analysis, those patients with a baseline MRI with at least one Gd-enhancing lesion and nine T2 lesions had a two-year risk of suffering a second event of 56% in the placebo group and 21% in the AVONEX treatment group.
Croatian: U post-hoc analizama, bolesnici kojima je na početku ispitivanja MRI pokazala najmanje jednu Gd-pozitivnu leziju i devet T2 lezija imaju dvogodišnji rizik pojave drugog događaja za 56% u placebo grupi i 21% u grupi liječenoj AVONEXOM.
English: Pack size: box of four or twelve pre-filled syringes of 0.5 ml.
Croatian: Veličina pakiranja: kutija sa četiri ili dvanaest napunjenih štrcaljki volumena 0,5 ml.
English: • Attach the needle by pressing it onto the glass pen tip.
Croatian: • Pričvrstite iglu pritisnuvši je na stakleni vrh brizgalice s uloškom
English: Tip: Do not hold the pen cover.
Croatian: Savjet: Nemojte držati zatvarač brizgalice.
English: Store the Avonex pen in the original package to protect from light.
Croatian: Avonex Pen čuvati u originalnom pakiranju radi zaštite od svjetlosti.
English: Avonex pen, injection needle and pen cover.
Croatian: Avonex Pen, igla za injekciju i zaštitni pokrov za brizgalicu.
English: Avonex Pen contains a pre-filled syringe of Avonex and should only be used following adequate training.
Croatian: Avonex Pen sadrži napunjenu štrcaljku Avonexa, i smije se jedino koristiti nakon odgovarajuće obuke.
English: • Look through the oval display window.
Croatian: • Pogledajte kroz ovalni prozorčić za prikaz lijeka.
English: If you get any symptoms of depression: - Feeling unusually sad, anxious or worthless.
Croatian: osjećate se neuobičajeno tužno, tjeskobno ili bezvrijedno.
English: Each AVOSTARTCLIP should be used once and then discarded along with any remaining AVONEX in the syringe.
Croatian: Svaki se AVOSTARTCLIP smije koristiti samo jednom, a zatim ga treba baciti zajedno s ostatkom AVONEXA u štrcaljki.
English: Laboratory abnormalities are associated with the use of interferons.
Croatian: Abnormalnosti koje se javljaju u laboratorijskim nalazima povezane su s primjenom interferona.
English: What you need to know before you use AVONEX Do not use AVONEX
Croatian: Što morate znati prije nego počnete primjenjivati AVONEX Nemojte primjenjivati AVONEX
English: You should only have one injection of Avonex, once a week.
Croatian: Trebali biste primiti samo jednu injekciju Avonexa, jednom tjedno.
English: Reproductive system and breast disorders uncommon metrorrhagia, menorrhagia
Croatian: Poremećaji reproduktivnog sustava i dojki manje često metroragija, menoragija
English: Musculoskeletal and connective tissue disorders common not known muscle cramp, neck pain, myalgia2, arthralgia, pain in extremity, back pain, muscle stiffness, musculoskeletal stiffness systemic lupus erythematosus, muscle weakness, arthritis
Croatian: Poremećaji mišićno-koštanog sustava i vezivnog tkiva često nepoznato grč mišića, bol u vratu, mialgija2, artralgija, bol u ekstremitetima, bol u leđima, ukočenost mišića, mišićno-koštana ukočenost sistemski eritematozni lupus, slabost mišića,
English: Patients with an EDSS of 1.0 to 3.5 at entry were included in the clinical trial.
Croatian: U kliničko istraživanje su bili uključeni bolesnici koji su na početku studije imali EDSS od 1,0 do 3,5.
English: - Epilepsy or other seizure disorders not controlled by medication
Croatian: - Epilepsiju ili druge vrste napadaja koji nisu kontrolirani lijekovima - Ozbiljne probleme s bubrezima ili jetrom
English: If you have trouble handling the syringe, ask your doctor who may be able to help.
Croatian: Ako imate problema pri rukovanju štrcaljkom, zatražite od svog liječnika da Vam pomogne.
English: (may affect up to 1 in 1,000 people) - Difficulty breathing.
Croatian: (mogu se javiti u manje od 1 na 1000 osoba)
English: The frequencies of adverse reactions are expressed in patient-years, according to the following categories:
Croatian: Učestalosti nuspojava izražene su u bolesnik-godinama prema sljedećim kategorijama:
English: Immune system disorders not known anaphylactic reaction, anaphylactic shock, hypersensitivity reactions (angioedema, dyspnoea, urticaria, rash, pruritic rash)
Croatian: Poremećaji imunološkog sustava nepoznato anafilaktična reakcija, anafilaktički šok, reakcije preosjetljivosti (angioedem, dispneja, urtikarija, osip i osip praćen svrbežom)
English: Do not use if it is out-of-date.
Croatian: Nemojte koristiti ako je istekao rok valjanosti.
English: (may affect up to 1 in 10 people) - Loss of appetite - Feeling weak and tired - Difficulty sleeping - Depression - Flushing - Runny nose
Croatian: - Gubitak apetita - Osjećaj slabosti i umora - Teškoće u spavanju