FrancophonIA/ELRC3.0 huggingface dataset:
English: • to treat patients with chronic heart failure when therapy with specific medicines calledangiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower highblood pressure) is not considered suitable by your doctor.
Slovenian: • za zdravljenje bolnikov s kroničnim srčnim popuščanjem, če zdravnik meni, da zdravljenje z zaviralci angiotenzinske konvertaze (zaviralci ACE, zdravila za zniževanje krvnega tlaka) ni primerno.
English: Hypertensive patients with left-ventricular hypertrophy In a controlled clinical trial in 9193 hypertensive patients 55 to 80 years of age with left-ventricular hypertrophy the following adverse events were reported:
Slovenian: Hipertenzivni bolniki s hipertrofijo levega prekata V kontroliranem kliničnem preskušanju pri 9193 hipertenzivnih bolnikih, starih 55 do 80 let, s hipertrofijo levega prekata so poročali o naslednjih neželenih učinkih:
English: • In controlled clinical trials in approximately 3300 adult patients 18 years of age and older for essential hypertension
Slovenian: • V kontroliranih kliničnih preskušanjih pri približno 3300 odraslih bolnikih, starih 18 let in več, z esencialno hipertenzijo
English: Losartan potassium
Slovenian: Kalijev losartanat
English: Remove the screw cap, place the push-in bottle neck adaptor on the bottle, and re-cap the bottle.
Slovenian: Odstranite zamašek, na plastenko namestite nastavek za vrat plastenke in ponovno zamašite plastenko.
English: If you accidentally take too much COZAAR oral suspension, contact your doctor immediately.
Slovenian: Če ste vzeli večji odmerek zdravila COZAAR, kot bi smeli Če slučajno vzamete preveč peroralne suspenzije COZAAR, se takoj posvetujte z zdravnikom.
English: • a 240 ml amber polyethylene terephthalate (PET) bottle with polypropylene child resistant closure for mixing the suspension,
Slovenian: • 240 ml rumeno-rjava PET plastenka (polyethylene terephthalate - polietilenijev tereftalat) s polipropilensko za otroke varno zaporko za pripravo suspenzije
English: The use of losartan is contraindicated during the 2nd and 3rd trimester of pregnancy (see section 4.3 and
Slovenian: Uporaba losartana je kontraindicirana v 2. in 3. trimesečju nosečnosti (glejte poglavji 4.3 in 4.4).
English: Powder microcrystalline cellulose (E460) lactose monohydrate pregelatinized maize starch magnesium stearate (E572) hydroxypropyl cellulose (E463) hypromellose (E464) titanium dioxide (E171)
Slovenian: Prašek mikrokristalna celuloza (E460) laktoza monohidrat predgelirani koruzni škrob magnezijev stearat (E572) hidroksipropilceluloza (E463) hipromeloza (E464) titanov dioksid (E171)
English: Cardiac disorder: Uncommon: palpitations, angina pectoris
Slovenian: Srčne bolezni: občasne: palpitacije, angina pektoris
English: • In a controlled clinical trial in 1513 type 2 diabetic patients 31 years of age and older with proteinuria
Slovenian: • V kontroliranem kliničnem preskušanju pri 1513 bolnikih, starih 31 let in več, s sladkorno boleznijo tipa 2 in proteinurijo
English: Very Common:
Slovenian: zelo pogosti:
English: Neither losartan nor the active metabolite can be removed by haemodialysis.
Slovenian: Niti losartana niti njegovega aktivnega presnovka ni možno odstraniti s hemodializo.
English: Use in children and adolescents (6 to 16 years):
Slovenian: Pediatrična hipertenzija Uporaba pri otrocih in mladostnikih (6 do 16 let):
English: As with other medicinal products that affect the renin-angiotensin-aldosterone system, increases in blood urea and serum creatinine have also been reported in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney; these changes in renal function may be reversible upon discontinuation of therapy.
Slovenian: Tako kot pri drugih zdravilih, ki vplivajo na sistem renin-angiotenzinaldosteron, so o zvišanju sečnine v krvi in zvišanju kreatinina v serumu poročali tudi pri bolnikih z obojestranskim zoženjem ledvične arterije ali zoženjem arterije ene same delujoče ledvice.
English: • In a controlled clinical trial in approximately 3900 patients 20 years of age and older with chronic heart failure
Slovenian: • V kontroliranem kliničnem preskušanju pri približno 3900 bolnikih, starih 20 let in več, s kroničnim srčnim popuščanjem
English: Plasma clearance of losartan and its active metabolite is about 600 ml/min and 50 ml/min, respectively.
Slovenian: Plazemski očistek losartana je približno 600 ml/min, njegovega aktivnega presnovka pa 50 ml/min.
English: Concomitant use of losartan and ACE-inhibitors has shown to impair renal function.
Slovenian: Pokazalo se je, da sočasna uporaba losartana in zaviralcev ACE okvari ledvice.
English: If your heart failure has beenstabilised with an ACE inhibitor you should not be switched to losartan.
Slovenian: Če je srčno popuščanje stabilno ob zdravljenju z zaviralcem ACE, vam zdravnik zdravila ne sme zamenjati za losartan.
English: Patients with heart failure who have been stabilised with an ACE inhibitor should not be switched to losartan.
Slovenian: Bolnikom s srčnim popuščanjem, katerih stanje je stabilno ob jemanju zaviralca ACE, zdravila ne smemo zamenjati z losartanom.
English: Powder and solvent for oral suspension.
Slovenian: Prašek in vehikel za peroralno suspenzijo.
English: After suspension in solvent, COZAAR is an offwhite liquid.
Slovenian: Po suspendiranju v vehiklu je zdravilo COZAAR sivo-bela tekočina.
English: No difference in exposure was found with concomitant treatment with fluvastatin (weak inhibitor of CYP2C9).
Slovenian: Pri sočasnem zdravljenju s fluvastatinom (šibek zaviralec CYP2C9) niso ugotovili nobenih razlik v izpostavljenosti.
English: In a controlled clinical trial in approximately 3900 patients 20 years of age and older with cardiac insufficiency the following adverse events were reported:
Slovenian: V kontroliranem kliničnem preskušanju pri približno 3900 bolnikih, starih 20 let in več, s srčno insuficienco so poročali o naslednjih neželenih učinkih:
English: What COZAAR contains
Slovenian: Kaj vsebuje zdravilo COZAAR
English: Paediatric Hypertension
Slovenian: Pediatrična hipertenzija
English: Uncommon: symptomatic hypotension (especially in patients with intravascular volume depletion, e.g. patients with severe heart failure or under treatment with high-dose diuretics), dose-related orthostatic effects, rash.
Slovenian: Žilne bolezni: občasne: simptomatska hipotenzija (posebej pri bolnikih z zmanjšanim intravaskularnim volumnom, npr. bolnikih s hudim srčnim popuščanjem ali bolnikih, ki se zdravijo z velikimi odmerki diuretikov), od odmerka odvisni ortostatski učinki, izpuščaj
English: -Losartan is also not recommended in children with hepatic impairment (see also section 4.4).
Slovenian: - Losartana ne priporočamo tudi za uporabo pri otrocih z jetrno okvaro (glejte tudi poglavje 4.4).
English: If goal blood pressure (< 140/90 mmHg) was not reached, hydrochlorothiazide (12.5 mg) was added first and, if needed, the dose of Losartan or atenolol was then increased to 100 mg once daily.
Slovenian: Če ciljnega krvnega tlaka (< 140/90 mmHg) niso dosegli, so najprej dodali hidroklorotiazid (12,5 mg), potem pa so, če je bilo potrebno, povečali odmerek losartana ali atenolola na 100 mg enkrat na dan. Za doseg ciljnega krvnega tlaka so, če je bilo potrebno, dodali še druge antihipertenzive, razen zaviralcev ACE, antagonistov angiotenzina II ali beta zaviralcev.
English: Cardiac disorders: not known: syncope, palpitations
Slovenian: Srčne bolezni: pogostnost ni znana: sinkopa, palpitacije
English: Microcrystalline cellulose (E460), carboxymethylcellulose sodium, citric acid anhydrous, purified water, xantham gum (E415), methylhydroxybenzoate (E218), sodium phosphate monobasic monohydrate, potassium sorbate, carrageenan calcium sulfate trisodium phosphate, flavor berry citrus sweet, glycerin, propylhydroxybenzoate (E216), sodium citrate anhydrous, saccharin sodium, sorbitol (E420)antifoam Af emulsion (contains water, polydimethylsiloxane, C-14-18, mono- and diglycerides, polyethylene glucol stearate, and polyethylene glycol).
Slovenian: Vehikel mikrokristalna celuloza (E460), natrijeva karboksimetilceluloza, citronska kislina, brezvodna, prečiščena voda, ksantanski gumi (E415), metilhidroksibenzoat (E218), natrijev dihidrogenfosfat monohidrat, kalijev sorbat, karagenan kalcijev sulfat trinatrijev fosfat, sladilo z okusom jagode in citrusa, glicerin, propilhidroksibenzoat (E216), natrijev citrat, brezvodni, natrijev saharinat, sorbitol (E420), protipenilna Af emulzija (vsebuje vodo, polidimetilsiloksan, C-14-18 mono- in di-gliceride, polietilenglikol stearat in polietilenglikol)
English: Muscoskeletal and connective tissue disorders: not known: myalgia, arthralgia
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva: pogostnost ni znana: mialgija, artralgija
English: The rise in trough diastolic blood pressure was the same in patients receiving placebo and in those continuing losartan at the lowest dose in each group, again suggesting that the lowest dose in each group did not have significant antihypertensive effect.
Slovenian: Povečanje diastoličnega krvnega tlaka tik pred naslednjim odmerkom je bilo enako pri bolnikih, ki so prejemali placebo, in bolnikih, ki so nadaljevali zdravljenje z losartanom z najmanjšim odmerkom v obeh skupinah.
English: Microcrystalline cellulose (E460), Lactose monohydrate, Pregelatinized maize starch, Magnesium stearate (E572), Hydroxypropyl cellulose (E463), Hypromellose (E464), and titanium dioxide (E171)
Slovenian: Prašek mikrokristalna celuloza (E460), laktoza monohidrat, predgelirani koruzni škrob, magnezijev stearat (E572), hidroksipropilceluloza (E463), hipromeloza (E464) in titanov dioksid (E171)
English: • a 10 ml oral dosing polypropylene syringe packed individually with a low density polyethylene push-in bottle neck adapter (PIBA) in a poly bag.
Slovenian: • 10 ml polipropilenska brizga za peroralno odmerjanje, pakirana skupaj z nastavkom za vrat plastenke iz polietilena nizke gostote (PIBA)
English: • One 473 ml bottle of solvent
Slovenian: • Plastenko s 473 ml vehikla
English: The following adverse events have been reported in post-marketing experience: Blood and lymphatic system disorders:
Slovenian: O naslednjih neželenih učinkih so poročali v okviru izkušenj z zdravilom v obdobju trženja: Bolezni krvi in limfatičnega sistema: pogostnost ni znana: anemija, trombocitopenija
English: Discard the excess solvent not used in the preparation of the suspension.
Slovenian: Ostanek vehikla, ki ga niste uporabili za pripravo suspenzije, zavrzite.
English: Vascular disorders: uncommon: hypotension, including orthostatic hypotension
Slovenian: Žilne bolezni: občasne: hipotenzija, vključno z ortostatsko hipotenzijo
English: The recommended starting dose in patients who weigh between 20 and 50 kg is 0.7 mg of losartan per kg of body weight administered once a day (up to 25 mg or 10 ml of COZAAR suspension).
Slovenian: Uporaba pri otrocih in mladostnikih (starih 6 do 16 let) Priporočeni začetni odmerek pri bolnikih, ki tehtajo med 20 in 50 kg, je 0,7 mg losartana na kg telesne teže enkrat na dan (do 25 mg ali 10 ml COZAAR suspenzije).
English: Treatment usually starts with 12.5 mg losartan (5 ml of COZAAR suspension) once a day.
Slovenian: Zdravljenje se običajno začne s 50 mg losartana (20 ml COZAAR suspenzije) enkrat na dan.
English: Generally, the dose should be increased weekly step-by-step (i.e., 12.5 mg daily during the first week, 25 mg daily during the second week, 50 mg daily during the third week) up to the usual maintenance dose of 50 mg losartan (20 ml of COZAAR suspension) once daily according to your condition.
Slovenian: Zdravljenje se običajno začne z 12,5 mg losartana (5 ml COZAAR suspenzije) enkrat na dan. Večinoma je treba odmerek povečati glede na vaše stanje, postopoma, tedensko (tj. 12,5 mg dnevno prvi teden, 25 mg dnevno drugi teden, 50 mg dnevno tretji teden) do običajnega vzdrževalnega odmerka 50 mg losartana (20 ml COZAAR suspenzije) enkrat na dan.
English: Muscoskeletal and connective tissue disorders: not known: back pain
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva: pogostnost ni znana: bolečine v hrbtu
English: In controlled clinical trials of approximately 3300 adult patients 18 years of age and older for essential hypertension with losartan the following adverse events were reported.
Slovenian: V kontroliranih kliničnih preskušanjih z losartanom pri približno 3300 odraslih bolnikih, starih 18 let in več, z esencialno hipertenzijo so poročali o naslednjih neželenih učinkih:
English: affects 1 to 10 users in 100
Slovenian: se pojavijo pri 1 do 10 od 100 uporabnikov občasni:
English: If you experience the following, stop taking losartan and tell your doctor immediately or go to the casualty department of your nearest hospital:
Slovenian: Losartan takoj prenehajte jemati in se posvetujte z zdravnikom ali pa takoj pojdite na urgenco, če se pri vas pojavi kaj od sledečega:
English: Before opening the sachet gently tap on the side of the sachet to facilitate transfer of the material.
Slovenian: Preden odprete vrečko, nežno potrkajte po eni strani vrečke, da umaknete prašek.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT Contains 500 mg losartan potassium
Slovenian: VSEBINA, IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ENOT Vsebuje 500 mg kalijevega losartanata.
English: Solvent microcrystalline cellulose carboxymethylcellulose sodium citric acid anhydrous purified water xantham gum (E415) methylhydroxybenzoate (E218) sodium phosphate monobasic monohydrate potassium sorbate (E202) carrageenan calcium sulfate, trisodium phosphate flavor berry citrus sweet glycerin propylhydroxybenzoate (E216) sodium citrate anhydrous saccharin sodium sorbitol (E420)antifoam AF emulsion (contains water, polydimethylsiloxane, C-14-18, mono- and diglycerides, polyethylene glucol stearate, and polyethylene glycol.)
Slovenian: Vehikel mikrokristalna celuloza natrijeva karboksimetilceluloza citronska kislina, brezvodna prečiščena voda ksantanski gumi (E415) metilhidroksibenzoat (E218) natrijev dihidrogenfosfat monohidrat kalijev sorbat (E202) karagenan kalcijev sulfat, trinatrijev fosfat sladilo z okusom jagode in citrusa glicerin propilhidroksibenzoat (E216) natrijev citrat, brezvodni natrijev saharinat sorbitol (E420) protipenilna AF emulzija (vsebuje vodo, polidimetilsiloksan, C-14-18 mono- in di-gliceride, polietilenglikol stearat in polietilenglikol.)
English: UAB Merck Sharp & Dohme, Geležinio Vilko 18A, LT- 01112 Vilnius, Lithuania
Slovenian: UAB Merck Sharp & Dohme, Geležinio Vilko 18A,
English: The solvent contains sorbitol.
Slovenian: Intoleranca za sorbitol/fruktozo Vehikel vsebuje sorbitol.
English: The sachet should NOT be rinsed.
Slovenian: Vrečke ne smete sprati.
English: The sachet should not be rinsed.
Slovenian: Vrečke NE smete sprati.
English: Safety data should be presented in the PSUR separated by age group and used formulation (e.g. tablets or oral suspension).
Slovenian: je treba podatke o varnosti predstaviti ločeno po starostni skupini in uporabljenem pripravku
English: Vascular disorders: not known: orthostatic hypotension
Slovenian: Žilne bolezni: pogostnost ni znana: ortostatska hipotenzija
English: Merck Sharp & Dohme Limited Hertford Road, Hoddesdon, Herts EN11 9BU, United Kingdom
Slovenian: Merck Sharp & Dohme Ltd., Hertford Road, Hoddesdon, Hertfordshire EN11 9BU Velika Britanija
English: Box 581, 2003 PC Haarlem The Netherlands
Slovenian: P.O. Box 581, 2003 PC Haarlem
English: Treatment with losartan resulted in a 13.0 % risk reduction (p=0.021, 95 % confidence interval 0.77-0.98) compared with atenolol for patients reaching the primary composite endpoint.
Slovenian: Zdravljenje z losartanon je v primerjavi z atenololom tveganje za primarni sestavljeni opazovani dogodek zmanjšalo za 13,0 % (p = 0,021; 95-odstotni interval zaupanja 0,77-0,98).
English: Place the screw cap on the bottle and shake the contents well to disperse.
Slovenian: Plastenko zaprite z zamaškom in stresajte,da se vsebina lepo porazdeli.
English: Merck Sharp & Dohme Romania S.R.L.
Slovenian: Romunija Merck Sharp & DohmeRomania S.R.L.
English: Merck Sharp & Dohme PO Box 581
Slovenian: Islandija Merck Sharp & Dohme PO Box 581
English: Losartan is not recommended in children with hepatic impairment (see section 4.2).
Slovenian: Losartana ne priporočamo za uporabo pri otrocih z okvaro jeter (glejte poglavje 4.2).
English: General disorders and administration site conditions: not known: flu-like symptoms
Slovenian: Splošne težave in spremembe na mestu aplikacije: pogostnost ni znana: gripi podobni simptomi
English: One bottle of reconstituted suspension (200 ml) contains 500 mg of losartan potassium.
Slovenian: Ena plastenka pripravljene suspenzije (200 ml) vsebuje 500 mg kalijevega losartanata.
English: The antihypertensive effect of losartan was established in a clinical study involving 177 hypertensive pediatric patients 6 to 16 years of age with a body weight > 20 kg and a glomerular filtration rate > 30 ml/ min/ 1.73 m2.
Slovenian: Antihipertenzivni učinek losartana so dokazali v klinični študiji, ki je zajela 177 hipertenzivnih pediatričnih bolnikov, starih 6 do 16 let, s telesno maso > 20 kg in hitrostjo glomerulne filtracije > 30 ml/min/1,73 m2. Bolniki, ki so tehtali > 20 kg do < 50 kg, so prejemali bodisi 2,5, 25 ali 50 mg losartana na dan, bolniki, ki so tehtali > 50 kg, pa so prejemali bodisi 5, 50 ali 100 mg losartana na dan.
English: White to off-white powder.
Slovenian: Bel do sivo-bel prašek.
English: Adult Patients with high blood pressure and type 2 diabetes Treatment usually starts with 50 mg losartan (20 ml of COZAAR suspension) once a day.
Slovenian: Odrasli bolniki z visokim krvnim tlakom in s sladkorno boleznijo tipa 2 Zdravljenje se običajno začne s 50 mg losartana (20 ml COZAAR suspenzije) enkrat na dan. Odmerek se kasneje lahko poveča na 100 mg losartana (40 ml COZAAR suspenzije) enkrat na dan, glede na odziv krvnega tlaka.
English: Insert the dispenser into the adapter on the medication bottle until a tight seal is made between the bottle and the adapter.
Slovenian: Brizgo vstavite v nastavek na plastenki z zdravilom tako, da se nastavek in plastenka dobro držita.
English: affects more than 1 user in 10
Slovenian: se pojavijo pri več kot 1 od 10 uporabnikov pogosti:
English: Member State Marketing Authorisation Holder Invented name Losartan potassium
Slovenian: Izmišljeno ime Kalijev losartanat
English: Merck Sharp & Dohme GmbH Donau-City-Straße 6, 1220 Wien, Austria
Slovenian: Donau-City-Straße 6, 1220 Dunaj, Avstrija
English: COZAAR and associated names (see Annex I) 2.5 mg/ml powder and solvent for oral suspension [See Annex I - To be completed nationally]
Slovenian: COZAAR in povezana imena (glejte Dodatek I) 2,5 mg/ml prašek in vehikel za peroralno suspenzijo [Glejte Dodatek I - Izpolni država članica]
English: Nervous system disorders: uncommon: dizziness, headache rare: paraesthesia
Slovenian: Bolezni živčevja: občasne: omotica, glavobol redke: parestezija
English: Skin and subcutaneous tissue disorders: not known: urticaria, pruritus, rash
Slovenian: Bolezni kože in podkožja: pogostnost ni znana: urtikarija, srbenje, izpuščaj
English: haemoglobin, haematocrit), a rise in urea-N in the serum and occasional rises in serum creatinine, a decrease in heart weight (without a histological correlate) and gastrointestinal changes (mucous membrane lesions, ulcers, erosions, haemorrhages).
Slovenian: V študijah toksičnosti pri ponavljajočih se odmerkih je uporaba losartana povzročila zmanjšanje eritrocitnih indeksov (števila eritrocitov, hemoglobina, hematokrita), povečanje količine N-sečnine v serumu in občasno zvišanje kreatinina v serumu, zmanjšanje mase srca (brez histološke povezave) in spremembe v prebavilih (poškodbe, razjede, erozije in krvavitve mukozne membrane).
English: Vascular disorders: common: hypotension
Slovenian: Žilne bolezni: pogoste: hipotenzija
English: Respiratory, thoracic and mediastinal disorders: not known: cough
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora: pogostnost ni znana: kašelj
English: Each sachet contains 500 mg of losartan potassium powder.
Slovenian: Ena vrečka vsebuje 500 mg praška kalijevega losartanata.
English: The following components are packed in a kit:
Slovenian: Pakiranje vsebuje naslednje komponente:
English: Both biliary and urinary excretions contribute to the elimination of losartan and its metabolites.
Slovenian: K izločanju losartana in njegovih presnovkov prispevata tako izločanje z žolčem kot izločanje preko ledvic.
English: Belgium Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Brussels, Belgium
Slovenian: Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B1180 Bruselj, Belgija
English: No initial dosage adjustment is necessary in patients with renal impairment and in haemodialysis patients.
Slovenian: Uporaba pri bolnikih z ledvično okvaro in bolnikih na hemodializi Pri bolnikih z ledvično okvaro in bolnikih na hemodializi začetnega odmerka ni treba prilagoditi.
English: May cause allergic reactions (possibly delayed).
Slovenian: Metilhidroksibenzoat in propilhidroksibenzoat Lahko povzročita alergijske reakcije (lahko zapoznele).
English: Luxembourg Merck Sharp & Dohme BV - Chaussée de Waterloo 1135 - B-1180 Brussels, Belgium
Slovenian: Luksemburg Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B-1180 Bruselj, Belgija
English: One ml of suspension contains 2.5 mg of losartan potassium.
Slovenian: En ml suspenzije vsebuje 2,5 mg kalijevega losartanata.
English: Shake the bottle well before use.
Slovenian: Pred uporabo plastenko dobro pretresite.
English: Nervous system disorders: not known: migraine
Slovenian: Bolezni živčevja: pogostnost ni znana: migrena
English: affects less than 1 user in 10000
Slovenian: se pojavijo pri manj kot 1 od 10.000 uporabnikov neznani:
English: Uncommon: somnolence, headache, sleep disorders
Slovenian: Bolezni živčevja: pogoste: omotica, vrtoglavica občasne: zaspanost, glavobol, motnje spanja
English: C/ Josefa Valcárcel, 38
Slovenian: MERCK SHARP AND DOHME DE ESPAÑA, S.A. C/ Josefa Valcárcel, 38
English: Luxembourg Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Brussels, Belgium
Slovenian: Luksemburg Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B1180 Bruselj, Belgija
English: Belgium Merck Sharp & Dohme BV -Chaussée de Waterloo 1135 - B-1180 Brussels, Belgium
Slovenian: Merck Sharp & Dohme BVChaussée de Waterloo 1135 - B-1180 Bruselj, Belgija
English: A low dose of hydrochlorothiazide should be added and/ or the dose of losartan should be increased to 100 mg once daily based on blood pressure response.
Slovenian: Običajni začetni odmerek je 50 mg losartana enkrat na dan. Glede na odziv krvnega tlaka je treba dodati majhen odmerek hidroklorotiazida in/ali odmerek losartana povečati na 100 mg enkrat na dan.
English: affects 1 to 10 users in 1000
Slovenian: se pojavijo pri 1 do 10 od 1.000 uporabnikov redki:
English: • A single aluminum foil sachet filled with powder containing 500 mg losartan potassium The sachet material consists of the following materials, from outside to inside and product contact layer: PET/Ink/ Adhesive/ Foil/ Adhesive/PE
Slovenian: Vrečka je iz naslednjih materialov (od zunanje do notranje strani, ki je v stiku z zdravilom): PET/črnilo/adheziv/folija/adheziv/PE
English: Replace the original cap onto the bottle.
Slovenian: Na plastenko namestite originalni zamašek.
English: Hepatobiliary disorders: rare: hepatitis not known: liver function abnormalities
Slovenian: Bolezni jeter, žolčnika in žolčevodov: redke: hepatitis pogostnost ni znana: nenormalno delovanje jeter
English: Unless continued AIIRA therapy is considered essential, patients planning pregnancy should be changed to alternative anti-hypertensive treatments which have an established safety profile for use in pregnancy.
Slovenian: Pri bolnicah, ki načrtujejo nosečnost, je treba čimprej preiti na alternativno antihipertenzivno zdravljenje z uveljavljenim varnostnim profilom za uporabo v nosečnosti; razen, če se oceni, da je nadaljnje zdravljenje z AIIRA-jem nujno.