FrancophonIA/ELRC3.0 huggingface dataset:
English: Pharmacogenetics: In patients who are poor CYP2C19 metabolisers, clopidogrel at recommended doses forms less of the active metabolite of clopidogrel and has a smaller effect on platelet function.
Danish: Farmakogenetik: Hos patienter med nedsat CYP2C19-metabolisme omdannes en mindre del af den anbefalede dosis af clopidogrel til den aktive metabolit og har derfor en mindre effekt på trombocytfunktionen.
English: Intracranial bleeding (some cases were reported with fatal outcome, especially in elderly), headache, paraesthesia, dizziness
Danish: Intrakraniel blødning (nogle med dødelig udgang, især hos ældre), hovedpine, paræstesier, svimmelhed
English: • ST segment elevation acute myocardial infarction in medically treated patients eligible for thrombolytic therapy
Danish: • Akut myokardieinfarkt med elevation af ST-segmentet hos medicinsk behandlede patienter, der er egnede til trombolytisk behandling
English: The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation.
Danish: Clopidogrels aktive metabolit hæmmer selektivt bindingen af adenosindiphosphat (ADP) til dets trombocyt P2Y12-receptor og den efterfølgende ADP-medierede aktivering af glykoprotein (GP)IIb- IIIa-komplekset, hvorved trombocytaggregationen hæmmes.
English: Colitis (including ulcerative or lymphocytic colitis), stomatitis, acute pancreatitis in the context of a hypersensitivity reaction due to acetylsalicylic acid*
Danish: Colitis (inklusive colitis ulcerosa og lymfocytisk colitis), stomatitis, akut pankreatitis i forbindelse med en overfølsomhedsreaktion på grund af acetylsalicylsyre
English: • valproic acid, valproate or carbamazepine, medicines to treat some forms of epilepsy,
Danish: • valproinsyre, valproat eller carbamazepin, medicin til behandling af bestemte typer epilepsi,
English: The primary outcome, a composite of cardiovascular death, stroke, urgent revascularization, and BARC (Bleeding Academic Research Consortium) bleeding ≥2 at 1 year post ACS, occurred in 43 patients (13.4%) in the de-escalated DAPT group and in 85 patients (26.3%) in the unchanged DAPT group (p<0.01).
Danish: Det primære resultat sammensat af kardiovaskulær død, slagtilfælde, akut revaskularisering og BARC (Bleeding Academic Research Consortium) blødning ≥ 2 ved 1-år efter ACS, forekom hos 43 patienter (13,4 %) i de-eskaleret DAPT gruppen og hos 85 patienter (26,3 %) i den uændrede DAPT-gruppe (p < 0,01).
English: Metabolism and nutrition disorders
Danish: Metaboliske og ernæringsmæssige lidelser
English: Do not take Clopidogrel/Acetylsalicylic acid Mylan during third trimester of pregnancy.
Danish: Du må ikke tage Clopidogrel/Acetylsalicylic acid Mylan under graviditetens tredje trimester.
English: Serious haemorrhage, haemorrhage of operative wound, vasculitis (including Henoch-Schönlein purpura*), hypotension
Danish: Alvorlig blødning, blødning i operationssår, vaskulitis (inklusive Henoch-Schönlein purpura
English: There are no fertility data with clopidogrel/acetylsalicylic acid.
Danish: Der findes ingen fertilitetsdata for clopidogrel/acetylsalicylsyre.
English: Bleeding events defined as all BARC occurred in 30 patients (9.3%) in the deescalated DAPT group and in 76 patients (23.5%) in the unchanged DAPT group (p<0.01).
Danish: Blødninger defineret som BARC forekom hos 30 patienter (9,3 %) i de-eskaleret DAPT gruppen og hos 76 patienter (23,5 %) i den uændrede DAPT gruppe (p < 0,01).
English: Renal failure*, acute renal impairment (especially in patients with existing renal impairment, heart decompensation, nephritic syndrome, or concomitant treatment with diuretics) *, glomerulonephritis, blood creatinine increased
Danish: *, akut nyreinsufficiens (særligt hos patienter med eksisterende nedsat nyrefunktion, kardial dekompensation, nefrotisk syndrom eller samtidig behandling med diuretika) glomerulonefrit, forhøjet blodkreatinin
English: Since SSRIs affect platelet activation and increase the risk of bleeding, the concomitant administration of SSRIs with clopidogrel should be undertaken with caution.
Danish: Da SSRI'er påvirker trombocytaktiveringen og øger risikoen for blødning, skal der udvises forsigtighed ved samtidig administration af SSRI'er og clopidogrel.
English: Fifteen percent (15.0%) of patients in the clopidogrel plus ASA group and 21.7% in the group treated with ASA alone reached the primary endpoint, representing an absolute reduction of 6.7% and a 36% odds reduction in favour of clopidogrel (95% CI: 24, 47%; p <0.001), mainly related to a reduction in occluded infarct-related arteries.
Danish: 15,0 % af patienterne i clopidogrel plus ASA-gruppen og 21,7 % i gruppen behandlet med ASA alene opnåede det primære endepunkt, hvilket viste en absolut reduktion på 6,7 % og en odds-reduktion på 36 % til fordel for clopidogrel (95 % CI: 24; 47 %; p <0,001), der hovedsageligt var relateret til en reduktion af infarkt-relaterede okkluderede arterier.
English: • the varicella vaccine, a medicine used to prevent chickenpox or shingles, within 6 weeks of taking Clopidogrel/Acetylsalicylic acid Mylan, or if you have active chickenpox or shingles infection (see section 2 ‘Children and adolescents'),
Danish: • bliver vaccineret mod skoldkopper eller helvedesild indenfor 6 uger efter brug af Clopidogrel/Acetylsalicylic acid Mylan, eller hvis du har/får skoldkopper eller helvedsild (se afsnit 2 ”Børn og unge”),
English: Rare side effect (may affect up to 1 in 1000 people): Vertigo, enlarged breasts in males.
Danish: Sjældne bivirkninger (kan påvirke op til 1 ud af 1.000 patienter): Svimmelhed (fornemmelse af at snurre rundt), forstørrede bryster hos mænd.
English: The 2x2 factorial design COMMIT trial included 45,852 patients presenting within 24 hours of the onset of the symptoms of suspected MI with supporting ECG abnormalities (i.e. ST elevation, ST
Danish: COMMIT-studiet, som var designet med 2×2 faktorer, inkluderede 45.852 patienter, der var til rådighed inden for 24 timer efter indtrådte symptomer, som var mistænkt for at være MI, og hvor EKG-anomalier (dvs. ST-elevation, ST-depression eller venstresidig grenblok) understøttede dette.
English: Poly (vinyl alcohol) (partially hydrolysed) Titanium dioxide (E171)
Danish: Polyvinylalkohol (delvist hydrolyseret) Titandioxid (E171)
English: The CURE study included 12,562 patients with non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), and presenting within 24 hours of onset of the most recent episode of chest pain or symptoms consistent with ischaemia.
Danish: CURE-undersøgelsen omfattede 12.562 patienter med akut koronarsyndrom uden forhøjelse af STsegmentet (ustabil angina pectoris eller myokardieinfarkt uden forekomst af Q-takker), som indfandt sig inden for 24 timer efter starten på den seneste episode med brystsmerter eller symptomer, der svarede til iskæmi.
English: Physicians should remain alert for signs of GI ulceration and bleeding, even in the absence of previous GI symptoms.
Danish: Lægen bør fortsat være opmærksom på tegn på GI-ulceration og blødning, også hvis patienten ikke tidligere har haft gastrointestinale symptomer.
English: Immune system disorders
Danish: Lidelser i immunsystemet
English: The incidence of major bleeding was similar between groups.
Danish: Forekomsten af større blødninger var ens i de to grupper.
English: Clopidogrel is first metabolised to a 2-oxo-clopidogrel intermediate metabolite.
Danish: Clopidogrel metaboliseres først til en 2-oxo-clopidogrel-metabolit.
English: Hydrogenated castor oil Starch pregelatinized Stearic acid
Danish: Hydrogeneret ricinusolie Stivelse, pregelatineret Stearinsyre
English: Clopidogrel/Acetylsalicylic acid Mylan is indicated for the secondary prevention of atherothrombotic events in adult patients already taking both clopidogrel and acetylsalicylic acid (ASA).
Danish: Clopidogrel/Acetylsalicylic acid Mylan er indiceret til sekundær forebyggelse af aterotrombotiske hændelser hos voksne patienter, der allerede tager både clopidogrel og acetylsalicylsyre (ASA).
English: In CLARITY, there was an overall increase in bleeding in the clopidogrel plus ASA group vs. the group taking ASA alone.
Danish: I CLARITY var der en generel stigning i antallet af blødninger i clopidogrel plus ASA-gruppen versus ASA-gruppen.
English: You have been prescribed Clopidogrel/Acetylsalicylic acid Mylan in place of the two separate medicines, clopidogrel and ASA, to help prevent blood clots because you have experienced a severe type of chest pain known as ‘unstable angina' or heart attack (myocardial infarction).
Danish: Du har fået ordineret Clopidogrel/Acetylsalicylic acid Mylan i stedet for de to indholdsstoffer clopidogrel og acetylsalicylsyre enkeltvist for at forebygge blodpropper, fordi du har haft en alvorlig form for smerter i brystet (ustabil angina pectoris) eller et hjerteanfald (myokardieinfarkt).
English: If you take more Clopidogrel/Acetylsalicylic acid Mylan than you should Contact your doctor or the nearest hospital emergency department because of the increased risk of bleeding.
Danish: Hvis du har taget for meget Clopidogrel/Acetylsalicylic acid Mylan Kontakt din læge eller tag på den nærmeste skadestue på grund af den øgede blødningsrisiko.
English: More than 30,000 patients entered into clinical trials with clopidogrel plus ASA at maintenance doses lower than or equal to 325 mg, and received a variety of concomitant medicinal products including diuretics, beta blockers, ACE Inhibitors, calcium antagonists, cholesterol lowering agents, coronary vasodilators, antidiabetic agents (including insulin), antiepileptic agents and GPIIb/IIIa antagonists without evidence of clinically significant adverse interactions.
Danish: Flere end 30.000 patienter, som indgik i kliniske studier med clopidogrel plus ASA ved vedligeholdelsesdoser på 325 mg eller lavere, fik en lang række ledsagende lægemidler såsom diuretika, betablokkere, ACE-hæmmere, calciumantagonister, kolesterolsænkende midler, vasodilatatorer med effekt på koronarkarrene, antidiabetika (inklusive insulin), antiepileptika samt GPIIb/IIIa-hæmmere, uden at der blev påvist klinisk signifikante uønskede interaktioner.
English: Following absorption, the ASA in Clopidogrel/Acetylsalicylic acid Mylan is hydrolysed to salicylic acid with peak plasma levels of salicylic acid occurring within 1 hour of dosing, such that plasma levels of ASA are essentially undetectable 1.5-3 hours after dosing.
Danish: Efter absorption bliver ASA i Clopidogrel/Acetylsalicylic acid Mylan hydrolyseret til salicylsyre med peak-plasmakoncentration af salicylsyre inden for 1 time efter dosering, sådan at plasmaniveauet af ASA er så godt som udetekterbart 1,5-3 timer efter dosering.
English: Salicylic acid in Clopidogrel/Acetylsalicylic acid Mylan has a plasma half-life of approximately 2 hours.
Danish: Salicylsyren i Clopidogrel/Acetylsalicylic acid Mylan har en plasmahalveringstid på ca. 2 timer.
English: The safety and efficacy of clopidogrel plus ASA have been evaluated in three double-blind studies involving over 61,900 patients: the CURE, CLARITY and COMMIT studies, comparing clopidogrel plus ASA to ASA alone, both treatments given in combination with other standard therapy.
Danish: Sikkerheden og virkningen af clopidogrel plus ASA er blevet evalueret i 3 dobbeltblindede studier, der omfattede mere end 61.900 patienter i CURE-, CLARITY- og COMMIT-undersøgelserne, hvor clopidogrel plus ASA sammenlignes med ASA alene.
English: Experimental data suggest that ibuprofen may inhibit the effect of low dose aspirin on platelet aggregation when they are dosed concomitantly.
Danish: Eksperimentelle data tyder på, at ibuprofen kan hæmme effekten af lave doser acetylsalicylsyre på trombocytaggregation ved samtidig administration.
English: The ASA in Clopidogrel/Acetylsalicylic acid Mylan is rapidly hydrolysed in plasma to salicylic acid, with a half-life of 0.3 to 0.4 hours for ASA doses from 75 to 100 mg. Salicylic acid is primarily conjugated in the liver to form salicyluric acid, a phenolic glucuronide, an acyl glucuronide, and a number of minor metabolites.
Danish: ASA i Clopidogrel/Acetylsalicylic acid Mylan hydrolyseres hurtigt i plasma til salicylsyre, med en halveringstid på 0,3 til 0,4 timer for ASA-doser fra 75 - 100 mg. Salicylsyre konjugeres primært i leveren og danner salicylsyre, et fenolglukuronid, et acylglukuronid og et antal underordnede metabolitter.
English: Depending on your condition, your doctor will determine the length of time for which you need to take Clopidogrel/Acetylsalicylic acid Mylan.
Danish: Ud fra din sygdom vil lægen bestemme, hvor lang tid du skal tage Clopidogrel/Acetylsalicylic acid Mylan.
English: Kounis syndrome (vasospastic allergic angina / allergic myocardial infarction) in the context of a hypersensitivity reaction due to acetylsalicylic acid* or clopidogrel**
Danish: Kounis syndrom (vasospastisk allergisk angina/allergisk myokardieinfarkt) i forbindelse med en allergisk reaktion på grund af acetylsalicylsyre eller clopidogrel
English: If you become pregnant while taking Clopidogrel/Acetylsalicylic acid Mylan, consult your doctor immediately as it is recommended not to take Clopidogrel/Acetylsalicylic acid Mylan while you are pregnant.
Danish: Hvis du bliver gravid, mens du tager Clopidogrel/Acetylsalicylic acid Mylan, skal du omgående kontakte din læge, da det frarådes at tage Clopidogrel/Acetylsalicylic acid Mylan under graviditet.
English: • probenecid, benzbromarone, or sulfinpyrazone, medicines used to treat gout,
Danish: • probenecid, benzbromaron eller sulfinpyrazon, lægemidler til behandling af urinsur gigt,
English: • fluconazole or voriconazole, medicines to treat fungal infections,
Danish: • fluconazol eller voriconazol, der anvendes til behandling af svampeinfektioner,
English: Mylan S.A.S Tel: +33 4 37 25 75 00
Danish: Mylan S.A.S Tél : +33 4 37 25 75 00
English: Bullous dermatitis (toxic epidermal necrolysis, Stevens Johnson Syndrome, erythema multiforme, acute generalised exanthematous pustulosis (AGEP)), angioedema, druginduced hypersensitivity syndrome, drug rash with eosinophilia and systemic symptoms (DRESS), rash erythematous or exfoliative, urticaria, eczema, lichen planus, fixed eruption*
Danish: Bulløs dermatitis (toksisk epidermal nekrolyse, StevensJohnsons syndrom, erythema multiforme, akut generaliseret eksantematøs pustulose (AGEP)), angioødem, lægemiddelinduceret overfølsomhed, medikamentelt udslæt med eosinofili og systemiske symptomer (DRESS), erytematøst eller eksfoliativt udslæt, urticaria, eksem, lichen planus, fixed drug eruption
English: Clopidogrel active metabolite pharmacokinetics and antiplatelet effects, as measured by ex vivo platelet aggregation assays, differ according to CYP2C19 genotype.
Danish: Farmakokinetikken og den antitrombotiske effekt, målt ved ex vivo trombocytaggregationsundersøgelse, adskiller sig alt efter CYP2C19-genotype.
English: • repaglinide, medicine to treat diabetes,
Danish: • repaglinid, medicin til behandling af sukkersyge (diabetes),
English: • if you suffer from severe liver disease.
Danish: • hvis du lider af en alvorlig leversygdom.
English: Jaundice (yellowing of skin and/or eyes); burning in stomach and/or oesophagus (gullet); severe abdominal pain with or without back pain; fever, breathing difficulties sometimes associated with cough; generalised allergic reactions (for example, overall sensation of heat with sudden general discomfort until fainting); swelling in the mouth; blisters of the skin; skin allergy; sore mouth (stomatitis); decrease in blood pressure; confusion; hallucinations; joint pain; muscular pain; changes in taste or loss of taste of foods, inflammation of small vessels.
Danish: Gulsot (gulfarvning af hud og/eller øjne); brændende fornemmelse i maven og/eller spiserøret; alvorlige mavesmerter med eller uden rygsmerter; feber, åndedrætsbesvær indimellem ledsaget af hoste; generelle allergiske reaktioner (f.eks. varmefølelse over hele kroppen med pludselig almen utilpashed og eventuelt besvimelse); hævelse i munden; blærer på huden; allergiske hudreaktioner; ømhed i munden (stomatitis); blodtryksfald; forvirring; hallucinationer; ledsmerter; muskelsmerter; smagsforstyrrelser eller mangel på smagssans, betændelse i små kar.
English: 28 film-coated tablets 30 film-coated tablets
Danish: 28 filmovertrukne tabletter 30 filmovertrukne tabletter
English: In patients concomitantly receiving nicorandil and NSAIDs including ASA and LAS, there is an increased risk for severe complications such as gastrointestinal ulceration, perforation and haemorrhage (see section 4.4).
Danish: Hos patienter, der samtidig får nicorandil og NSAID'er, herunder ASA og LAS, er der en øget risiko for alvorlige komplikationer i form af gastrointestinal blødning, perforation og blødning (se pkt.
English: Side effects with frequency not known (frequency cannot be estimated from the available data): Ulcer perforation, ringing in the ears, hearing loss, sudden life-threatening allergic or hypersensitivity reactions with chest or abdominal pain, kidney disease, low blood sugar, gout (a condition of painful, swollen joints caused by uric acid crystals) and worsening of food allergies, a particular form of anaemia (low number of red blood cells) (see section 2 ‘Warnings and precautions'), swelling.
Danish: Bivirkninger med ikke kendt hyppighed (kan ikke vurderes ud fra forhåndenværende data): Perforeret mavesår, ringen for ørerne, nedsat hørelse, pludselige, livstruende allergiske reaktioner eller overfølsomhedsreaktioner med bryst- eller mavesmerter, nyresygdom, lavt blodsukker, urinsur gigt (en tilstand med smertefulde, hævede led forårsaget af urinsyrekrystaller), forværring af madallergi og en særlig form for anæmi (lavt antal røde blodceller) (se afsnit 2 'Advarsler og forsigtighedsregler'), hævelse.
English: Clopidogrel/Acetylsalicylic acid Mylan should be used with caution in patients with a history of peptic ulcer or gastroduodenal haemorrhage or minor upper GI symptoms as this may be due to gastric ulceration which may lead to gastric bleeding.
Danish: Clopidogrel/Acetylsalicylic acid Mylan bør anvendes med forsigtighed hos patienter med peptisk ulcus, gastroduodenal blødning eller mindre øvre gastrointestinale symptomer i anamnesen, da disse kan være tegn på gastrisk ulceration, der kan føre til gastrisk blødning.
English: As a dual antiplatelet agent, Clopidogrel/Acetylsalicylic acid Mylan should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery or other pathological conditions and in patients receiving treatment with other NSAIDs including Cox-2 inhibitors, heparin, glycoprotein IIb/IIIa inhibitors, selective serotonin reuptake inhibitors (SSRIs), thrombolytics, or other medicinal products associated with bleeding risk such as pentoxifylline (see section 4.5).
Danish: Som dobbelt antitrombotisk middel skal Clopidogrel/Acetylsalicylic acid Mylan anvendes med forsigtighed til patienter med øget risiko for blødning pga. traumer, kirurgi eller andre patologiske tilstande samt til patienter, der samtidigt behandles med andre NSAID'er inklusive Cox-2 hæmmere, heparin, glykoprotein IIb/IIIa-hæmmere, selektive serotoningenoptagelseshæmmere (SSRI'er), trombolytika eller andre lægemidler forbundet med risiko for blødning, såsom pentoxifyllin (se pkt.
English: If the use of Clopidogrel/Acetylsalicylic acid Mylan is discontinued, patients may benefit with continuation of one antiplatelet medicinal product.
Danish: Hvis Clopidogrel/Acetylsalicylic acid Mylan seponeres, kan patienterne have gavn af fortsat behandling med et trombocytfunktionshæmmende lægemiddel.
English: Clopidogrel/Acetylsalicylic acid Mylan prolongs bleeding time and should be used with caution in patients who have lesions with a propensity to bleed (particularly gastrointestinal and intraocular).
Danish: Clopidogrel/Acetylsalicylic acid Mylan forlænger blødningstiden og bør anvendes med forsigtighed hos patienter med læsioner, der indebærer øget blødningstendens (specielt gastrointestinalt og intraokulært).
English: Clopidogrel/Acetylsalicylic acid Mylan contains clopidogrel and acetylsalicylic acid (ASA) and belongs to a group of medicines called antiplatelet medicinal products.
Danish: Clopidogrel/Acetylsalicylic acid Mylan indeholder clopidogrel og acetylsalicylsyre (ASA) og tilhører en gruppe medicin, der kaldes blodfortyndende medicin.
English: • This medicinal product must be administered under close medical supervision in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to risk of haemolysis (see section 4.8).
Danish: • På grund af risiko for hæmolyse skal dette lægemiddel administreres under omhyggelig medicinsk supervision til patienter med glucose-6-fosfatdehydrogenase (G6PD)-mangel (se pkt.
English: The desiccant should not be eaten.
Danish: Tørremidlet må ikke sluges.
English: Contains lactose and Allura Red AC. See leaflet for further information.
Danish: Indeholder lactose og Allura Red AC.
English: • Non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction) including patients undergoing a stent placement following percutaneous coronary intervention
Danish: • Akut koronarsyndrom uden elevation af ST-segmentet (ustabil angina pectoris eller myokardieinfarkt uden forekomst af Q-takker) inklusive patienter, som får indsat stent efter perkutan koronar intervention
English: Glycerol monocaprylocaprate (E422) Sodium lauril sulfate
Danish: Glycerol monocaprylocaprat (E422)
English: Patients were randomized to receive either prasugrel 5 or 10 mg/d (Days 0-14) (n=1306), or prasugrel 5 or 10 mg/d (Days 0-7) then de-escalated to clopidogrel 75 mg/d (Days 8-14) (n=1306), in combination with ASA (<100 mg/day).
Danish: Patienterne blev randomiseret til at modtage enten prasugrel 5 eller 10 mg/d (dag 0-14) (n = 1306) eller prasugrel 5 eller 10 mg/d (dag 0-7), derefter de-eskaleret til clopidogrel 75 mg/d (dag 8-14) (n = 1309) i kombination med ASA (< 100 mg/dag).
English: Clopidogrel/Acetylsalicylic acid Mylan has no or negligible influence on the ability to drive and use machines.
Danish: Clopidogrel/Acetylsalicylic acid Mylan påvirker ikke eller kun i ubetydelig grad evnen til at føre motorkøretøj og betjene maskiner.
English: Clopidogrel is a prodrug, one of whose metabolites is an inhibitor of platelet aggregation.
Danish: Clopidogrel er et prodrug, hvor en af metabolitterne hæmmer trombocytaggregationen.
English: From the beginning of the sixth month of pregnancy, all prostaglandin synthesis inhibitors may expose: the foetus to: cardiopulmonary toxicity (with premature closure of the ductus arteriosus and pulmonary hypertension); renal dysfunction, which may progress to renal failure with oligo-hydroamniosis;
Danish: • udsætte fostret for: - Kardiopulmonal toksicitet (med præmatur lukning af ductus arteriosus og pulmonal hypertension); - Renal dysfunktion, der kan udvikle sig til nyresvigt med oligo-hydroamniose;
English: HDPE bottles with white opaque polypropylene screw cap with aluminium induction sealing liner wad and desiccant containing 100 film-coated tablets.
Danish: HDPE tabletbeholdere med hvide, gennemsigtige skruelåg af polypropylen med påsat aluminiumsforseglingsindlæg i kartonæsker, der indeholder 100 filmovertrukne tabletter.
English: Acetylsalicylic acid inhibits platelet aggregation by irreversible inhibition of prostaglandin cyclooxygenase and thus inhibits the generation of thromboxane A2, an inducer of platelet aggregation and vasoconstriction.
Danish: Acetylsalicylsyre hæmmer trombocytaggregation ved irreversibel hæmning af prostaglandincyklooxygenase og hæmmer derved dannelsen af tromboxan A2, en inducer af trombocytaggregation og vasokonstriktion.
English: Patients received clopidogrel (75 mg/day, n=22,961) plus ASA (162 mg/day), or ASA alone (162 mg/day) (n=22,891), for 28 days or until hospital discharge.
Danish: Patienterne fik clopidogrel (75 mg/dag, n = 22.961) plus ASA (162 mg/dag) eller ASA alene (162 mg/dag) (n = 22.891) i 28 dage eller indtil udskrivelse fra hospitalet.
English: Eye bleeding (conjunctival, ocular, retinal)
Danish: Øjenblødning (konjunktival, okulær, retinal)