FrancophonIA/ELRC3.0 huggingface dataset:
English: As with antibiotic therapy in general, administration of ceftriaxone should be continued for 48 - 72 hours after the patient has become afebrile or evidence of bacterial eradication has been achieved.
Slovenian: Kot velja na splošno za zdravljenje z antibiotikom, je treba z uporabo ceftriaksona nadaljevati še 48-72 ur po tem, ko postane bolnik afebrilen ali ko so doseženi vidni znaki eradikacije bakterije.
English: Gonorrhoea 500 mg as a single intramuscular dose.
Slovenian: Gonoreja 500 mg v obliki enega intramuskularnega odmerka.
English: Binding is saturable and the bound portion decreases with rising concentration (up to 85 % at a plasma concentration of 300 mg/l).
Slovenian: Vezava je nasičena, delež vezave pa se z večanjem koncentracije manjša (do 85 % pri 300 mg/l koncentracije v plazmi).
English: • Rocephin may interfere with some types of blood glucose tests - please check with your doctor.
Slovenian: • Zdravilo Rocephin lahko vpliva na nekatere vrste krvnih preiskav za glukozo - posvetujte se z zdravnikom.
English: • You have other illnesses, such as haemolytic anaemia (a reduction in your red blood cells that may make your skin pale yellow and cause weakness or breathlessness).
Slovenian: • če imate druge bolezni, na primer hemolitično anemijo (zmanjšanje rdečih krvnih celic v vaši krvi, kar vašo kožo obarva svetlo rumeno in povzroča šibkost ali pomanjkanje sape).
English: Severe allergic reactions (not known, frequency cannot be estimated from the available data) If you have a severe allergic reaction, tell a doctor straight away.
Slovenian: Hude alergijske reakcije (neznana, pogostnosti ni mogoče oceniti iz razpoložljivih podatkov) Če imate hudo alergijsko reakcijo, to takoj povejte zdravniku.
English: This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.
Slovenian: To povzroči prekinitev biosinteze celične stene (peptidoglikana), kar povzroči lizo in smrt bakterijske celice.
English: There is evidence from animal studies that high doses of ceftriaxone calcium salt led to formation of concrements and precipitates in the gallbladder of dogs and monkeys, which proved to be reversible.
Slovenian: Študije na živalih dokazujejo, da so visoki odmerki ceftriakson-kalcijeve soli povzročili nastanek konkrementov in oborin v žolčniku psov in opic, ki pa so se izkazale za reverzibilne.
English: What you need to know before you are given Rocephin
Slovenian: Kaj morate vedeti, preden boste dobili zdravilo Rocephin
English: Cases of renal precipitation have been reported, primarily in children older than 3 years of age and who have been treated with either high daily doses (e.g. ≥ 80 mg/kg/day) or total doses exceeding 10 grams and who presented with other risk factors (e.g. fluid restrictions or confinement to bed).
Slovenian: Poročali so o primerih obarjanja v ledvicah, zlasti pri otrocih, starejših kot 3 leta, ki so bili zdravljeni z velikimi dnevnimi odmerki (npr. ≥ 80 mg/kg/dan) ali skupnimi odmerki nad 10 gramov in pri katerih so bili prisotni drugi dejavniki tveganja (npr. tekočinske omejitve ali nepokretnost).
English: Anaerobes
Slovenian: Anaerobi
English: • A false positive result for galactosaemia (an abnormal build up of the sugar galactose).
Slovenian: • lažno pozitivni rezultati za galaktozemijo (nenormalno kopičenje sladkorja galaktoze)
English: What Rocephin is and what it is used for
Slovenian: Kaj je zdravilo Rocephin in za kaj ga uporabljamo
English: If you have a severe infection, your doctor will give you a higher dose up to 100 mg for each kg of body weight to a maximum of 4 g once a day.
Slovenian: Če imate resno okužbo, vam bo zdravnik dal večji odmerek, do 100 mg za vsak kg telesne mase, vendar največ 4 g, enkrat na dan.
English: It belongs to a group of medicines called cephalosporins.
Slovenian: Sodi v skupino zdravil, imenovanih cefalosporini.
English: The maximum plasma concentration after a single intramuscular dose of 1 g is about 81 mg/l and is reached in 2 - 3 hours after administration.
Slovenian: Največja koncentracija v plazmi po enem intramuskularnem odmerku 1 g je približno 81 mg/l in je dosežena v 2-3 urah po dajanju.
English: Not known (Frequency cannot be estimated from the available data)
Slovenian: Neznana (pogostnosti ni mogoče oceniti iz razpoložljivih podatkov)
English: Syphilis
Slovenian: Sifilis
English: Penetration into particular tissues
Slovenian: Prehajanje v določena tkiva
English: The recommended treatment durations vary and national or local guidelines should be taken into consideration.
Slovenian: Priporočeno trajanje zdravljenja se razlikuje; upoštevati je treba nacionalne ali lokalne smernice.
English: In severe renal and hepatic insufficiency, close clinical monitoring for safety and efficacy is advised (see section 4.2).
Slovenian: Pri hudi ledvični in jetrni insuficienci se priporoča skrbno klinično spremljanje varnosti in učinkovitosti (glejte poglavje 4.2).
English: • Children with a body weight of 50 kg or more should be given the usual adult dose.
Slovenian: • Otroci s telesno maso 50 kg ali več morajo prejeti odmerek, ki je običajen za odrasle.
English: Rocephin must not be given to babies if:
Slovenian: Zdravila Rocephin se ne sme dajati dojenčkom:
English: • Difficulty in breathing (bronchospasm).
Slovenian: • težave z dihanjem (bronhospazem),
English: • A neurological condition that may occur in neonates with severe jaundice (kernicterus).
Slovenian: • nevrološko stanje, ki se lahko pojavi pri novorojencih s hudo zlatenico (kernikterus),
English: Safety and effectiveness of Rocephin in neonates, infants and children have been established for the dosages described under Posology and Method of Administration (see section 4.2).
Slovenian: Varnost in učinkovitost zdravila Rocephin pri novorojencih, dojenčkih in otrocih je bila dokazana za odmerke, opisane v poglavju Odmerjanje in način uporabe (glejte poglavje 4.2).
English: See information in the Summary of Product Characteristics of lidocaine, especially contraindications.
Slovenian: Glejte informacije v povzetku glavnih značilnosti zdravila za lidokain, zlasti kontraindikacije.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from ceftriaxone therapy, taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Slovenian: Odločiti se je treba med prenehanjem dojenja in prenehanjem/prekinitvijo zdravljenja s ceftriaksonom, pri čemer je treba upoštevati koristi dojenja za otroka in koristi zdravljenja za mater.
English: Streptococcus pyogenes (Group A) Streptococcus agalactiae (Group B) Streptococcus pneumoniae Viridans Group Streptococci
Slovenian: Streptococcus pyogenes (skupina A) Streptococcus agalactiae (skupina B) Streptococcus pneumoniae Streptokoki skupine Viridans
English: the skin or soft tissues.
Slovenian: • kože ali mehkih tkiv,
English: As with all beta-lactam antibacterial agents, serious and occasionally fatal hypersensitivity reactions have been reported (see section 4.8).
Slovenian: Kot pri vseh betalaktamskih protimikrobnih učinkovinah, so poročali o resnih in občasno smrtnih preobčutljivostnih reakcijah (glejte poglavje 4.8).
English: Rocephin is made up by the doctor, pharmacist or nurse and will not be mixed with or given to you at the same time as calcium-containing injections.
Slovenian: Zdravilo Rocephin pripravi zdravnik, farmacevt ali medicinska sestra in se ga ne meša ali daje sočasno z injekcijami, ki vsebujejo kalcij.
English: Italy: Rocefin
Slovenian: Italija: Rocefin
English: Based on literature reports, ceftriaxone is not compatible with amsacrine, vancomycin, fluconazole and aminoglycosides.
Slovenian: Na podlagi poročil iz literature ceftriakson ni združljiv z amsakrinom, vankomicinom, flukonazolom in aminoglikozidi.
English: • A type of antibiotic called an aminoglycoside.
Slovenian: • Vrsta antibiotika, imenovana aminoglikozid.
English: • to treat patients with low white blood cell counts (neutropenia) who have fever due to bacterial infection.
Slovenian: • za zdravljenje bolnikov z nizkim številom belih krvnih celic (nevtropenija), ki imajo povišano telesno temperaturo zaradi bakterijske okužbe,
English: Precipitation of ceftriaxone calcium salt in the gallbladder has been observed, primarily in patients treated with doses higher than the recommended standard dose.
Slovenian: Opazili so obarjanje ceftriakson-kalcijeve soli v žolčniku, predvsem pri bolnikih, zdravljenih z odmerki, ki so bili višji od priporočenega standardnega odmerka.
English: An 8 - 15 % increase in mean peak plasma concentration (Cmax) is seen on repeated administration; steady state is reached in most cases within 48 - 72 hours depending on the route of administration.
Slovenian: Pri ponavljajočem dajanju se povprečna najvišja koncentracija v plazmi (Cmax) poveča za 8-15 %; stanje dinamičnega ravnovesja se v večini primerov doseže v roku 48-72 ur, odvisno od načina uporabe.
English: Intravenous doses of 50 mg/kg or more in infants and children up to 12 years of age should be given by infusion.
Slovenian: Intravenske odmerke 50 mg/kg ali več je treba dojenčkom in otrokom, starim do 12 let, dati z infuzijo.
English: • The signs may include a severe rash that develops quickly, with blisters or peeling of the skin and possibly blisters in the mouth.
Slovenian: • Znaki lahko vključujejo hud izpuščaj, ki se razvije hitro, z mehurji ali luščenjem kože in možnimi mehurji v ustih.
English: Indications for neonates 0-14 days that require specific dosage schedules:
Slovenian: Indikacije za novorojence 0-14 dni, za katere so potrebne posebne sheme odmerjanja:
English: Most patients presented with risk factors for biliary stasis and biliary sludge e.g. preceding major therapy, severe illness and total parenteral nutrition.
Slovenian: Pri večini bolnikov so bili prisotni dejavniki tveganja za zastoj žolča in za žolčno usedlino, npr. pomembno predhodno zdravljenje, huda bolezen in popolna parenteralna prehrana.
English: • Sudden swelling of the face, throat, lips or mouth.
Slovenian: • nenadno oteklost obraza, žrela, ustnic ali ust.
English: Plasma protein binding is about 95 % at plasma concentrations below 100 mg/l.
Slovenian: Vezava na beljakovine v plazmi je približno 95 % pri koncentracijah v plazmi pod 100 mg/l.
English: Interaction with calcium containing products
Slovenian: Medsebojno delovanje z zdravili, ki vsebujejo kalcij
English: The pharmacokinetics of ceftriaxone are non-linear and all basic pharmacokinetic parameters, except the elimination half-life, are dose dependent if based on total drug concentrations, increasing less than proportionally with dose.
Slovenian: Farmakokinetične lastnosti ceftriaksona so nelinearne in vsi osnovni farmakokinetični parametri, razen razpolovnega časa izločanja, so odvisni od odmerka, če temeljijo na skupnih koncentracijah zdravila, ter se z odmerkom povečujejo manj kot sorazmerno.
English: This is also due to an increase in plasma free fraction of ceftriaxone contributing to the observed paradoxical increase in total drug clearance, with an increase in volume of distribution paralleling that of total clearance.
Slovenian: To je tudi posledica povečanja prostih frakcij ceftriaksona v plazmi, kar prispeva k opaženemu paradoksalnemu povečanju skupnega očistka zdravila, s povečanjem volumna distribucije, ki je podobno povečanju skupnega očistka.
English: ** Twice daily (12 hourly) administration may be considered where doses greater than 2 g daily are administered.
Slovenian: **O dajanju zdravila dvakrat na dan (na 12 ur) razmislimo, ko so potrebni odmerki večji od 2 g na dan.
English: France: Rocephine
Slovenian: Francija: Rocephine
English: Solutions containing ceftriaxone should not be mixed with or added to other agents except those mentioned in section 6.6.
Slovenian: Raztopin, ki vsebujejo ceftriakson, se ne sme mešati z drugimi zdravili ali jih dodajati drugim učinkovinam razen s tistimi, ki so omenjena v poglavju 6.6.
English: Rocephin is an antibiotic given to adults and children (including newborn babies).
Slovenian: Zdravilo Rocephin je antibiotik, ki se daje odraslim in otrokom (vključno z novorojenci).
English: • Form of anaemia where red blood cells are destroyed (haemolytic anaemia).
Slovenian: • oblika anemije, pri kateri se uničujejo rdeče krvne celice (hemolitična anemija),
English: Rocephin can be administered by intravenous infusion over at least 30 minutes (preferred route) or by slow intravenous injection over 5 minutes, or by deep intramuscular injection.
Slovenian: Zdravilo Rocephin se lahko daje v obliki intravenske infuzije, ki traja vsaj 30 minut (priporočen način uporabe), počasne intravenske injekcije, ki traja 5 minut, ali z globoko intramuskularno injekcijo.
English: Adults and children over 12 years of age (≥ 50 kg)
Slovenian: Odrasli in otroci, stari več kot 12 let (≥ 50 kg)
English: • The maximum daily dose is not to be more than 50 mg for each kg of the baby's weight.
Slovenian: • Največji dnevni odmerek ne sme preseči 50 mg za vsak kg telesne mase otroka.
English: What Rocephin is and what it is used for What you need to know before you are given Rocephin How Rocephin is given
Slovenian: Kaj je zdravilo Rocephin in za kaj ga uporabljamo Kaj morate vedeti, preden boste dobili zdravilo Rocephin Kako se daje zdravilo Rocephin Možni neželeni učinki
English: Other medicines and Rocephin
Slovenian: Druga zdravila in zdravilo Rocephin
English: For pre-operative prophylaxis of surgical site infections, ceftriaxone should be administered 30-90 minutes prior to surgery.
Slovenian: Za predoperativno profilakso okužb mesta kirurškega posega se ceftriakson daje 30-90 minut pred kirurškim posegom.
English: In polymicrobial infections, where suspected pathogens include organisms resistant to ceftriaxone, administration of an additional antibiotic should be considered.
Slovenian: Pri polimikrobnih okužbah, kjer sum na povzročitelja bolezni vključuje organizme, odporne na ceftriakson, je treba razmisliti o uporabi dodatnega antibiotika.
English: In neonates, intravenous doses should be given over 60 minutes to reduce the potential risk of bilirubin encephalopathy (see section 4.3 and 4.4).
Slovenian: Pri novorojencih je treba intravenske odmerke dajati v času 60 minut, da se zmanjša možno tveganje za nastanek bilirubinske encefalopatije (glejte poglavji 4.3 in 4.4).
English: Do not mix with solutions that contain calcium, including Hartmann's, Ringers and Total Parenteral Nutrition
Slovenian: Ne mešajte z raztopinami, ki vsebujejo kalcij, vključno s Hartmannovo ali Ringerjevo raztopino in raztopino za popolno parenteralno prehrano.
English: Penetration is greatest when the meninges are inflamed.
Slovenian: Prehajanje je največje, kadar so možganske ovojnice vnete.
English: In patients with renal or hepatic dysfunction, the pharmacokinetics of ceftriaxone are only minimally altered with the half-life slightly increased (less than two fold), even in patients with severely impaired renal function.
Slovenian: Pri bolnikih z okvarjenim delovanjem ledvic ali jeter je farmakokinetika ceftriaksona le minimalno spremenjena, razpolovni čas pa nekoliko podaljšan (manj kot dvakrat), tudi pri bolnikih s hudo okvarjenim delovanjem ledvic.
English: You are allergic to lidocaine and you are to be given Rocephin as an injection into a muscle.
Slovenian: • če ste alergični na lidokain in boste zdravilo Rocephin prejeli v obliki injekcije v mišico.
English: You have ever had problems with your gut, in particular colitis (inflammation of the bowel).
Slovenian: Če ste kadar koli imeli težave s črevesjem, zlasti kolitis (vnetje črevesja).
English: During treatment with ceftriaxone, undesirable effects may occur (e.g. dizziness), which may influence the ability to drive and use machines (see section 4.8).
Slovenian: Med zdravljenjem s ceftriaksonom se lahko pojavijo neželeni učinki (npr. omotica), ki lahko vplivajo na sposobnost vožnje in upravljanja s stroji (glejte poglavje 4.8).
English: • You are on a low sodium diet.
Slovenian: • če ste na dieti z omejenim vnosom natrija.
English: Available data do not indicate the need for dose adjustment in mild or moderate liver function impairment provided renal function is not impaired.
Slovenian: Razpoložljivi podatki ne kažejo na potrebo po prilagoditvi odmerka pri blagi ali zmerni okvari delovanja jeter, če delovanje ledvic ni okvarjeno.
English: Ceftriaxone, like other antibiotics, may result in false-positive tests for galactosaemia.
Slovenian: Ceftriakson lahko, tako kot vsi drugi antibiotiki, povzroči lažno pozitivne rezultate testov za galaktozemijo.
English: In vitro studies demonstrated that neonates have an increased risk of precipitation of ceftriaxone-calcium compared to other age groups.
Slovenian: Študije in vitro so pokazale, da je pri novorojencih večje tveganje za oborine ceftriakson-kalcija v primerjavi z drugimi starostnimi skupinami.
English: See section 4.4
Slovenian: b Glejte poglavje 4.4.
English: Simultaneous administration of probenecid does not reduce the elimination of ceftriaxone.
Slovenian: Sočasna uporaba probenecida ne zmanjša izločanja ceftriaksona.
English: Rarely, severe, and in some cases, fatal, adverse reactions have been reported in pre-term and full-term neonates (aged < 28 days) who had been treated with intravenous ceftriaxone and calcium.
Slovenian: Redko so poročali o hudih in v nekaterih primerih smrtnih neželenih učinkih pri nedonošenih in donošenih novorojencih (starih < 28 dni), ki so bili zdravljeni z intravenskim ceftriaksonom in kalcijem.
English: The signs include sudden swelling of the throat or face which might make it difficult to breath or swallow, sudden swelling of the hands, feet and ankles, and a severe rash that develops quickly.
Slovenian: Znaki vključujejo nenadno oteklost žrela ali obraza, ki lahko povzroči težave z dihanjem ali požiranjem, nenadno oteklost rok, stopal in gležnjev, ter hiter razvoj hudega izpuščaja.
English: • outer membrane impermeability in Gram-negative organisms.
Slovenian: • neprepustnost zunanje membrane pri gramnegativnih organizmih,
English: Ceftriaxone has a limited spectrum of antibacterial activity and may not be suitable for use as a single agent for the treatment of some types of infections unless the pathogen has already been confirmed (see section 4.2).
Slovenian: Ceftriakson ima omejen spekter protimikrobnega delovanja in morda ni primeren kot edina učinkovina za zdravljenje nekaterih vrst okužb, razen če je bil povzročitelj bolezni že določen (glejte poglavje
English: The dose recommendations in syphilis, including neurosyphilis, are based on very limited data.
Slovenian: Priporočeni odmerki pri sifilisu, vključno z nevrosifilisom, temeljijo na zelo omejenih podatkih.
English: Antibacterial spectrum
Slovenian: Protimikrobni spekter
English: Severe skin rashes (not known, frequency cannot be estimated from the available data) If you get a severe skin rash, tell a doctor straight away.
Slovenian: Hudi kožni izpuščaji (neznana, pogostnosti ni mogoče oceniti iz razpoložljivih podatkov) Če dobite hud kožni izpuščaj, to takoj povejte zdravniku.
English: * In vitro studies have shown that ceftriaxone can displace bilirubin from its serum albumin binding sites leading to a possible risk of bilirubin encephalopathy in these patients.
Slovenian: * Študije in vitro so pokazale, da lahko ceftriakson izpodrine bilirubin iz mest vezave na albumin v serumu, kar pri teh bolnikih povzroči možno tveganje za bilirubinsko encefalopatijo.
English: Shadows, which have been mistaken for gallstones, have been detected on sonograms of the gallbladder and have been observed more frequently at ceftriaxone doses of 1 g per day and above.
Slovenian: Sence, ki jih je mogoče zamenjati za žolčne kamne, so odkrili na ultrazvoku žolčnika in so jih pogosteje opazili pri odmerkih ceftriaksona 1 g na dan ali več.
English: Intramuscular administration should be considered when the intravenous route is not possible or less appropriate for the patient.
Slovenian: Intramuskularne injekcije pridejo v poštev le, če intravensko dajanje ni možno ali pa je manj primerno za bolnika.
English: Ceftriaxone inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs).
Slovenian: Ceftriakson zavira sintezo celične stene bakterij po vezavi na penicilin-vezavne beljakovine (PBP, penicillin binding proteins).
English: • Changes in the results of blood tests for liver functions.
Slovenian: • spremenjeni rezultati krvnih preiskav za delovanje jeter
English: The dosages recommended for adults require no modification in older people provided that renal and hepatic function is satisfactory.
Slovenian: Odmerkov, priporočenih za odrasle, pri starejših bolnikih ni treba prilagajati, če je delovanje njihovih ledvic in jeter zadovoljivo.
English: Studies have shown that ceftriaxone, like some other cephalosporins, can displace bilirubin from serum albumin.
Slovenian: Študije so pokazale, da lahko ceftriakson, kot nekateri drugi cefalosporini, izpodrine bilirubin iz albumina v serumu.
English: Immune mediated haemolytic anaemia
Slovenian: Imunsko pogojena hemolitična anemija
English: This event may be symptomatic or asymptomatic, may lead to renal insufficiency and anuria, and is reversible upon discontinuation of ceftriaxone (see section 4.4).
Slovenian: Ta dogodek je lahko simptomatski ali asimptomatski, povzroči lahko ledvično insuficienco in anurijo, in je po prekinitvi uporabe ceftriaksona reverzibilen (glejte poglavje 4.4).
English: The high risk of precipitation in neonates is a result of their low blood volume and the longer half-life of ceftriaxone compared with adults (see sections 4.3, 4.4, and 5.2).
Slovenian: Veliko tveganje obarjanja pri novorojencih je posledica njihovega nizkega krvnega volumna in daljšega razpolovnega časa ceftriaksona v primerjavi z odraslimi (glejte poglavja 4.3, 4.4, in 5.2).
English: Peak ceftriaxone concentrations in CSF are reached approximately 4-6 hours after intravenous injection.
Slovenian: Največje koncentracije ceftriaksona v cerebrospinalni tekočini so dosežene približno 4-6 ur po intravenskem injiciranju.
English: Appropriate fluid and electrolyte management should be instituted (see section 4.4).
Slovenian: Uvesti je treba ustrezno uravnavanje tekočin in elektrolitov v telesu (glejte poglavje 4.4).
English: The dose recommendations in syphilis, including neurosyphilis, are based on limited data.
Slovenian: Priporočeni odmerki pri sifilisu, vključno z nevrosifilisom, temeljijo na omejenih podatkih.
English: 2 g powder for solution for infusion Intravenous use
Slovenian: 2 g prašek za raztopino za infundiranje intravenska uporaba
English: • Tell the person taking the sample that you have been given Rocephin.
Slovenian: • Osebi, ki jemlje vzorec, povejte, da se zdravite z zdravilom Rocephin.
English: Rocephin is contraindicated in premature neonates up to a postmenstrual age of 41 weeks (gestational age + chronological age).
Slovenian: Zdravilo Rocephin je kontraindicirano pri nedonošenih novorojencih do postmenstrualne starosti 41 tednov (gestacijska starost + kronološka starost).
English: Uncommon (≥ 1/1000 - < 1/100) Rare (≥ 1/10000 - < 1/1000)
Slovenian: Občasni (>1/1000 do <1/100): Redki (>1/10.000 do <1/1.000)
English: Mean peak ceftriaxone concentrations in CSF in patients with bacterial meningitis are reported to be up to 25 % of plasma levels compared to 2 % of plasma levels in patients with uninflamed meninges.
Slovenian: Poročali so, da so povprečne največje koncentracije ceftriaksona v cerebrospinalni tekočini pri bolnikih z bakterijskim meningitisom znašale do 25 % ravni v plazmi v primerjavi z 2 % ravni v plazmi pri bolnikih brez vnetih možganskih ovojnic.
English: The relatively modest increase in half-life in renal impairment is explained by a compensatory increase in non-renal clearance, resulting from a decrease in protein binding and corresponding increase in non-renal clearance of total ceftriaxone.
Slovenian: Razmeroma skromno povečanje razpolovnega časa pri ledvični okvari je mogoče razložiti s kompenzacijskim povečanjem neledvičnega očistka, ki ga povzroči zmanjšanje vezave na beljakovine in posledično povečanje neledvičnega očistka skupnega ceftriaksona.