FrancophonIA/ELRC3.0 huggingface dataset:
English: In each of the two studies, the proportion of subjects requiring supplemental SL BPN was significantly higher in the placebo group than in the Sixmo group (90.9% and 66.7% of subjects, with mean days of use per week of 2.17 and 1.27, in PRO-805 and PRO-806, respectively).
Estonian: Sixmo vajasid täiendavat keelealust buprenorfiini oluliselt suurem platseeborühmas kui Sixmo rühmas (uuringutes PRO-805 ja PRO-806 vastavalt 90,9% ja 66,7% uuringus osalejatest, keskmine kasutamispäevade arv nädalas oli 2,17 ja 1,27).
English: Non-palpable implants must be located prior to attempted removal.
Estonian: Palpeerides mitteleitavate implantaatide asukoht tuleb enne eemaldamist kindlaks teha.
English: Sixmo contains the active substance buprenorphine, which is a type of opioid medicine.
Estonian: Mis ravim on Sixmo ja milleks seda kasutatakse Sixmo sisaldab toimeainet buprenorfiini, mis on teatud tüüpi opioidravim.
English: Adverse drug reactions were categorized as implant or non-implant adverse reactions.
Estonian: Kõrvaltoimed jagati implantaadiga seotud ja implantaadiga mitteseotud kõrvaltoimeteks.
English: Each dose consists of four implants, for subcutaneous insertion in the inner side of the upper arm.
Estonian: Üks annus koosneb neljast õlavarre siseküljele subkutaanselt sisestatavast implantaadist.
English: Figure 12
Estonian: Joonis 12
English: Sixmo is contraindicated in patients with severe hepatic impairment.
Estonian: Sixmo on vastunäidustatud raske maksakahjustusega patsientidele.
English: There should be at least 5 mm between the incision and the implant when the implant is properly positioned.
Estonian: Kui implantaat on korrektselt paigaldatud, peab sisselõike ja implantaadi vahele jääma vähemalt 5 mm.
English: Higher doses may be required for analgesic effect.
Estonian: Valuvaigistava toime saavutamiseks võib olla vaja kasutada suuremaid annuseid.
English: Step 13: The patient should lie on their back, with the implant arm flexed at the elbow and externally rotated, so that the hand is positioned next to the head.
Estonian: Patsient peab lamama selili, implantaatidega käsivars küünarnukist üles painutatud ja pööratud väljapoole, nii et käelaba on pea kõrval.
English: Instructions for subcutaneous insertion of Sixmo
Estonian: Juhised Sixmo subkutaanseks sisestamiseks
English: If implants for repeat treatment are not inserted on the same day as removal of previous implants, individuals should be maintained on a fixed dose of 2 to 8 mg/day of sublingual buprenorphine, as clinically indicated, until repeat treatment occurs.
Estonian: Kui kordusravi implantaate ei sisestata eelmiste implantaatide eemaldamisega samal päeval, peavad isikud saama säilitusravi keelealuse buprenorfiini fikseeritud annusega 2...8 mg ööpäevas kuni kordusravi alustamiseni.
English: Apply an ice pack on the arm for 40 minutes every two hours for the first 24 hours, then as needed.
Estonian: Esimese 24 tunni jooksul asetage käsivarrele iga kahe tunni tagant 40 minutiks jääkott ja hiljem vajaduse korral.
English: Step 1: The patient should lie on their back, with the intended arm flexed at the elbow and externally rotated, so that the hand is positioned next to the head.
Estonian: Patsient peab lamama selili, vajalik käsivars küünarnukist üles painutatud ja pööratud väljapoole, nii et käelaba on pea kõrval.
English: Figure 17
Estonian: Joonis 17
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Outer carton (kit)
Estonian: VÄLISPAKENDIL PEAVAD OLEMA JÄRGMISED ANDMED Väliskarp (komplekt)
English: Figure 1: Cumulative Distribution Function of the Percentage of Urine Samples Negative for Opioids in Weeks 1-16, Study PRO-805 (ITT)
Estonian: Kumulatiivne jaotusfunktsioon opioidide suhtes negatiivse tulemusega uriiniproovide protsendist 1. kuni 16. nädalal uuringus PRO-805 (ITT)
English: Patients who may not be investigated using a magnetic resonance imaging (MRI) scan must not be allowed to receive Sixmo.
Estonian: Sixmot ei tohi paigaldada patsientidele, keda ei saa uurida magnetresonantstomograafia (MRT) uuringuga.
English: • have had an increased formation of scare tissue
Estonian: • kui teil on olnud suurenenud armkoe moodustumine.
English: Ask your doctor or pharmacist for advice in these cases.
Estonian: Neil juhtudel pidage nõu oma arsti või apteekriga.
English: • Liver damage, including liver failure, has been reported when using buprenorphine.
Estonian: • Buprenorfiini kasutamise ajal on teatatud maksakahjustusest, sh maksapuudulikkusest.
English: Talk to your doctor before using Sixmo if you have:
Estonian: Enne Sixmo kasutamist pidage nõu oma arsti või apteekriga, kui teil on:
English: Psychiatric disorders common insomnia, anxiety, hostility**, nervousness**, paranoia** uncommon depression, libido decreased, sleep disorder, apathy, euphoric mood, orgasmic sensation decreased, restlessness, irritability, drug dependence***, agitation***, thinking abnormal***
Estonian: aeg-ajalt depressioon, libiido vähenemine, unehäired, apaatia, eufooriline meeleolu, orgasmitunde vähenemine, rahutus, ärrituvus, ravimisõltuvus***, agitatsioon***, ebanormaalsed mõtted***
English: Instruct the patient to apply an ice pack to the arm for 40 minutes every two hours for first 24 hours, then as needed.
Estonian: Juhendage patsienti, et esimese 24 tunni jooksul tuleb iga kahe tunni tagant asetada käsivarrele 40 minutiks jääkott ja hiljem vajaduse korral.
English: Figure 2: Cumulative Distribution Function of the Percentage of Urine Samples Negative for Opioids in Weeks 1-24 (co-primary endpoint 1), Study PRO-806 (ITT Population)
Estonian: Kumulatiivne jaotusfunktsioon opioidide suhtes negatiivse tulemusega uriiniproovide protsendist 1. kuni 24. nädalal (esimene esmane kaastulemusnäitaja) uuringus PRO-806 (ITT-populatsioon)
English: • reduced sense of touch or sensation
Estonian: • puutetundlikkuse või tundlikkuse vähenemine
English: No Sixmo dose adjustment is therefore considered necessary for patients with renal impairment.
Estonian: Seetõttu ei ole neerukahjustusega patsientidel vaja Sixmo annust kohandada.
English: • constipation, nausea, vomiting, diarrhoea
Estonian: • kõhukinnisus, iiveldus, oksendamine, kõhulahtisus
English: Figure 14
Estonian: Joonis 14
English: Before administering Sixmo implants
Estonian: Enne Sixmo implantaatide manustamist
English: • enlarged prostate or narrowed urethra
Estonian: • suurenenud eesnääre või kitsenenud kusiti,
English: Apply a pressure bandage with sterile gauze to minimize bruising.
Estonian: Verevalumi tekke minimeerimiseks katke steriilse marlilapi ja rõhksidemega.
English: Retract the applicator, bevel-up, until the distal marking of the cannula is visible at the incision opening (the sharp tip remaining in the subcutaneous space).
Estonian: Hoides kaldotsast, tõmmake aplikaator välja, kuni sisselõike avast on näha kanüüli distaalne märk (terav ots jääb naha alla).
English: Medicinal product subject to special and restricted medical prescription.
Estonian: B. HANKE- JA KASUTUSTINGIMUSED VÕI PIIRANGUD Piiratud tingimustel väljastatav retseptiravim ja eriretsepti alusel väljastatav ravim.
English: If another set of implants is not inserted on the same day as the previous set is removed: A dose of between 2 and 8 mg buprenorphine daily, given under the tongue, is recommended until repeat treatment occurs.
Estonian: Kui vana komplekti eemaldamise päeval uut implantaatide komplekti ei sisestata, siis: on soovitatav manustada keele alla buprenorfiini annuses 2...8 mg ööpäevas kuni kordusravi alustamiseni.
English: Percentage of negative results
Estonian: Patsientide protsent
English: Equipment for subcutaneous insertion of Sixmo The following equipment is needed for implant insertion under aseptic conditions:
Estonian: Vahendid Sixmo subkutaanseks sisestamiseks Implantaadi sisestamiseks aseptilistes tingimustes on vaja järgmisi vahendeid:
English: These risks and the patient's stability in treatment for opioid dependence should be considered when determining whether Sixmo is appropriate for the patient.
Estonian: Patsiendile Sixmo sobivuse kindlaks tegemisel tuleb kaaluda neid riske ja patsiendi stabiilsust opioidisõltuvuse ravis.
English: • vulvovaginal fungal infection
Estonian: • kuseteede infektsioon
English: Step 3: Put on sterile gloves and check the function of the implant applicator by removing the obturator from the cannula and relocking it. Clean the insertion site with an antiseptic solution, such as chlorhexidine.
Estonian: Tõmmake kätte steriilsed kindad ja kontrollige implantaadi aplikaatori toimimist, eemaldades obturaatori kanüülist ja seda uuesti lukustades.
English: • fatigue, chills, weakness, increased muscle tone
Estonian: • väsimus, külmavärinad, nõrkus, lihasetoonuse suurenemine
English: Equipment for subcutaneous insertion of Sixmo
Estonian: Vahendid Sixmo subkutaanseks sisestamiseks
English: Buprenorphine should be used cautiously when co-administered with:
Estonian: Buprenorfiini tuleb manustada ettevaatlikult koos järgmiste ainetega.
English: Step 8: While holding the obturator in place on the arm, retract the cannula along the obturator, leaving the implant in place (Figure 11).
Estonian: Hoides obturaatorit käsivarrel paigal, tõmmake kanüül piki obturaatorit välja, nii et implantaat jääb oma kohale (joonis 11).
English: • drug dependence
Estonian: • ravimisõltuvus
English: DATE OF REVISION OF THE TEXT
Estonian: TEAVE PROTSEDUURI KOHTA
English: After removal of the implant, the doctor will apply a sterile gauze with a pressure bandage to minimize bruising.
Estonian: Pärast implantaatide eemaldamist katab arst eemaldamiskoha verevalumi vältimiseks steriilse marlilapi ja rõhksidemega.
English: Few cases of protrusion or expulsion of implants, mainly attributed to improper insertion technique, were reported in clinical studies with Sixmo (see section 4.4).
Estonian: Sixmo kliinilistes uuringutes teatati mõnest implantaadi esiletungimise- või väljasurumise juhust, mida seostati mittenõuetekohase sisestamistehnika kasutamisega (vt lõik 4.4).
English: CI=confidence interval, ITT=intent-to-treat, N=number of subjects, SE=standard error In the analysis of the CDF (co-primary endpoint 1), a statistically significant difference between treatments (p<0.0001) was seen, which was in favour of Sixmo.
Estonian: Kumulatiivse jaotusfunktsiooni (esimene esmane kaastulemusnäitaja) analüüsis täheldati statistiliselt olulist erinevust (p < 0,0001) ravide vahel Sixmo kasuks.
English: NAME OF THE MEDICINAL PRODUCT Sixmo 74.2 mg implant
Estonian: RAVIMPREPARAADI NIMETUS Sixmo 74,2 mg implantaat
English: Clean removal site with alcohol pad prior to marking the skin.
Estonian: Enne naha märgistamist puhastage eemalduskoht alkoholiga immutatud lapiga.
English: • are using naltrexone or nalmefene to treat alcohol or opioid dependence
Estonian: • kui te kasutate alkoholi- või opioidisõltuvuse raviks naltreksooni või nalmefeeni,
English: Most frequent implant adverse reactions were implant site pain, implant site pruritus, implant site haematoma, implant site haemorrhage, implant site erythema and implant site rash.
Estonian: Kõige sagedamini esinenud implantaadiga seotud kõrvaltoimed olid valu implanteerimiskohas, kihelus implanteerimiskohas, hematoom implanteerimiskohas, verejooks implanteerimiskohas, erüteem implanteerimiskohas ja lööve implanteerimiskohas.
English: • changes in blood levels increased enzyme levels: aspartate aminotransferase, gamma-glutamyltransferase, blood lactate dehydrogenase, lipase, amylase decreased enzyme levels: alkaline phosphatase increased bicarbonate level increased bilirubin level - a yellow breakdown substance of the blood pigment increased glucose level decreased cholesterol level decreased haematocrit - the percentage of blood cells on the blood volume decreased haemoglobin - the red blood cell pigment, increased mean cell haemoglobin increase in certain white blood cell count: monocyte, neutrophils decreased cell count: platelets, red blood cells, lymphocytes
Estonian: - hematokriti (vererakkude osakaal vere üldmahust) vähenemine hemoglobiini (vere punaliblede pigment) sisalduse vähenemine, vere punaliblede keskmise hemoglobiinisisalduse suurenemine vere teatud valgeliblede (monotsüüdid, neutrofiilid) arvu suurenemine rakkude arvu vähenemine: vereliistakud, vere punalibled, lümfotsüüdid
English: After insertion of the implants, the doctor will apply a sterile gauze with a pressure bandage to minimize bruising.
Estonian: Pärast implantaatide sisestamist katab arst sisestamiskoha verevalumi vältimiseks steriilse marlilapi ja rõhksidemega.
English: These underlying factors including confirmation of viral hepatitis status must be taken into consideration before prescribing Sixmo and during treatment.
Estonian: Enne Sixmo määramist ja ravi ajal tuleb nimetatud põhitegureid, sh viirushepatiidi olemasolu, arvesse võtta.
English: Skin and subcutaneous tissue disorders common hyperhidrosis uncommon cold sweat, dry skin, rash, skin lesion, ecchymosis*
Estonian: Naha ja nahaaluskoe kahjustused sage hüperhidroos aeg-ajalt külm higi, nahakuivus, lööve, nahalesioon, ekhümoos*
English: • sterile ruler
Estonian: • steriilne joonlaud,
English: • sedation
Estonian: • Imetamine
English: Step 18: Disposal of Sixmo implants should be in accordance with local requirements as it contains buprenorphine.
Estonian: Kuna Sixmo implantaadid sisaldavad buprenorfiini, tuleb need hävitada kohalike nõuete kohaselt.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each implant contains buprenorphine hydrochloride equivalent to 74.2 mg of buprenorphine.
Estonian: KVALITATIIVNE JA KVANTITATIIVNE KOOSTIS Üks implantaat sisaldab buprenorfiinvesinikkloriidi koguses, mis vastab 74,2 mg buprenorfiinile.
English: Rare but serious complications, including nerve damage and migration resulting in embolism and death, may result from improper insertion of drug implants in the upper arm. Additional complications may include local migration, protrusion, expulsion and implant breakage after insertion or during removal.
Estonian: Harvad, kuid rasked tüsistused on muu hulgas ravimiimplantaatide ebaõige sisestamise tagajärjel tekkida võivad närvikahjustus ja migratsioon, mis viib emboolia ja surmani.
English: The following equipment is needed for implant insertion under aseptic conditions:
Estonian: Implantaadi sisestamiseks aseptilistes tingimustes on vaja järgmisi vahendeid:
English: Supportive measures (including oxygen, vasopressors) should be employed in the management of circulatory shock and pulmonary oedema as indicated.
Estonian: Tsirkulatoorse šoki ja pulmonaalse ödeemi korral tuleb võtta asjakohased toetavad meetmed (sh hapnik, vasopressorid).
English: • hot flush, bruising, dilation of blood vessels
Estonian: • kuumahood, verevalumid, veresoonte laienemine
English: Cardiac arrest or arrhythmias will require advanced life support techniques.
Estonian: Südame seiskumise või arütmiate korral tuleb kasutada elustamise spetsiifilisi ravivõtteid.
English: Removal of Sixmo implants
Estonian: Sixmo implantaatide eemaldamine
English: Buprenorphine given under the tongue will be stopped 12 to 24 hours before insertion of Sixmo implants.
Estonian: Buprenorfiini manustamine keele alla lõpetatakse 12...24 tundi enne Sixmo implantaatide sisestamist.
English: Sixmo is formulated as a diversion and abuse deterrent formulation.
Estonian: Sixmo ravimvorm on välja töötatud ravimi kuritarvitamise ja selle kõrvaletoimetamise vältimiseks.
English: You may fell dizzy, drowsy and less alert.
Estonian: Võite tunda peapööritust, unisust ja tähelepanu hajumist.
English: Step 4: Lift the edge of the incision opening with the toothed forceps.
Estonian: Tõstke sisselõike ava serv hammastatud pintsettidega üles.
English: Schedule an appointment for the sutures to be removed.
Estonian: Leppige kokku visiit haavaniitide eemaldamiseks.
English: Apply liquid adhesive to the skin margins and allow to dry before closing the incision with the thin adhesive strip around 6 mm wide (butterfly strip).
Estonian: Enne sisselõike sulgemist ligikaudu 6 mm laiuse plaastriga (haavasulgur) kandke nahaservadele haavaliimi ja laske kuivada.
English: Retreatment with Sixmo implants
Estonian: Kordusravi Sixmo implantaatidega
English: Buprenorphine has the potential to be abused and is prone to criminal diversion.
Estonian: Buprenorfiini on võimalik kuritarvitada ja seetõttu võib esineda selle kõrvaletoimetamist.
English: • sterile fenestrated drapes
Estonian: • steriilsed augustatud kattelinad,
English: NAME OF THE MEDICINAL PRODUCT Sixmo 74.2 mg implant (buprenorphine)
Estonian: RAVIMPREPARAADI NIMETUS Sixmo 74,2 mg implantaat (buprenorfiin)
English: • eye discharge, blurred vision, lacrimal disorder
Estonian: • eritis silmast, nägemise hägustumine, pisaravoolu häire
English: • sterile fenestrated drape
Estonian: • steriilne augustatud kattelina,
English: Step 6: While lifting, gently advance the applicator subcutaneously along the channel marking on the skin.
Estonian: Samal ajal, kui te nõela otsaga tõstate nahka, lükake aplikaatorit subkutaanselt nahale joonistatud kanalimärkide järgi ettevaatlikult edasi.
English: • phenobarbital, carbamazepine, phenytoin: medicines to treat epilepsy and other illnesses
Estonian: • epilepsia ja muude haiguste ravimiseks kasutatavaid ravimeid fenobarbitaali, karbamasepiini, fenütoiini;
English: • abnormal mean cell volume
Estonian: • normist erinev rakkude keskmine kogus
English: Cases of acute hepatic injury (including fatal cases) have been reported with the active substance buprenorphine in opioid-dependent addicts both in clinical trials and in post marketing adverse reaction reports.
Estonian: Toimeaine buprenorfiiniga seoses on opioidisõltlastel nii kliinilistes uuringutes kui ka turuletulekujärgselt teatatud kõrvaltoimetena ägedate maksakahjustuste (sh letaalse lõppega) juhtudest.
English: Place an adhesive bandage over the incision.
Estonian: Asetage sisselõikekohale plaaster.
English: Table 4: Percentage of Opioid-Negative Urine Samples for Weeks 1 to 24, Study PRO-806
Estonian: Opioidide suhtes negatiivsete uriiniproovide protsent 1. kuni 24. nädalal uuringus PRO-806 (ITT) Negatiivsete tulemuste protsent
English: Side effects can occur with the following frequencies: Common, may affect up to 1 in 10 people
Estonian: Sage, võib esineda kuni ühel inimesel 10-st
English: Injury, poisoning and procedural complications common procedural pain*, procedural site reaction* uncommon post procedural complication (*), contusion (*), wound dehiscence*, migration of implanted drug***, device breakage***
Estonian: aeg-ajalt protseduurijärgne tüsistus (*), kontusioon (*), haava avanemine*, implanteeritud ravimi migreerumine***, seadme purunemine***
English: Sublingual buprenorphine should be discontinued 12 to 24 hours prior to insertion of four Sixmo implants.
Estonian: Keelealuse buprenorfiini manustamine tuleb lõpetada 12...24 tundi enne nelja Sixmo implantaadi sisestamist.
English: Treatment with Sixmo implants
Estonian: Ravi Sixmo implantaatidega
English: 4.5 Interaction with other medicinal products and other forms of interaction Buprenorphine should not be administered together with:
Estonian: 4.5 Koostoimed teiste ravimitega ja muud koostoimed
English: Nervous system disorders common headache, dizziness, somnolence, hypertonia**, syncope** uncommon hypoaesthesia, migraine, depressed level of consciousness, hypersomnia, paraesthesia, tremor
Estonian: Närvisüsteemi häired sage peavalu, peapööritus, unisus, hüpertoonia**, sünkoop**
English: Each implant contains buprenorphine hydrochloride equivalent to 74.2 mg of buprenorphine.
Estonian: Üks implantaat sisaldab buprenorfiinvesinikkloriidi koguses, mis vastab 74,2 mg buprenorfiinile .
English: Sublingual buprenorphine should be discontinued 12 to 24 hours prior to subcutaneous insertion of Sixmo implants.
Estonian: Keelealuse buprenorfiini manustamine tuleb lõpetada 12...24 tundi enne Sixmo implantaatide subkutaanset paigaldamist.
English: Step 14: Put on sterile gloves.
Estonian: Tõmmake kätte steriilsed kindad.
English: • excessive sleepiness
Estonian: • liigne unisus
English: Treatment must be under the supervision of a healthcare professional experienced in the management of opioid dependence/addiction.
Estonian: Ravi peab toimuma opioidisõltuvuse ravikogemusega meditsiinitöötaja järelevalve all.
English: Place the implant in a glass jar with a lid. Store it safely away from others, especially children.
Estonian: Hoidke seda ohutus, teistele inimestele, eriti lastele kättesaamatus kohas.
English: • latex, talc-free sterile gloves
Estonian: • talgita steriilsed latekskindad,
English: • have severly reduced liver function
Estonian: • kui teie maksatalitlus on tõsiselt vähenenud,
English: NAME OF THE MEDICINAL PRODUCT Sixmo 74.2 mg implant buprenorphine
Estonian: RAVIMPREPARAADI NIMETUS Sixmo 74,2 mg implantaat buprenorfiin
English: BATCH NUMBER Lot
Estonian: Sixmo'ga ravi
English: • cough, breathlessness
Estonian: • migreen, värinad
English: Frequency Adverse reactions Infections and infestations common viral infection, bronchitis**, infection**, influenza**, pharyngitis**, rhinitis** uncommon cellulitis, skin infection, peritonsillar abscess, rash pustular, urinary tract infection, vulvovaginal mycotic infection, implant site infection*, implant site abscess*
Estonian: aeg-ajalt tselluliit, nahainfektsioon, peritonsillaarabstsess, pustuloosne lööve, kuseteede infektsioon, vulvovaginaalne mükoinfektsioon, implanteerimiskoha infektsioon*, implanteerimiskoha abstsess*
English: • dry mouth, wind, indigestion, bloody stool
Estonian: • suukuivus, kõhupuhitus, seedehäired, veri väljaheites
English: Reconfirm the location of the implants by palpation.
Estonian: Kontrollige palpeerides uuesti implantaatide asukohta.
English: Musculoskeletal and connective disorders common bone pain**, myalgia** uncommon muscle spasms, limb discomfort, musculoskeletal pain, neck pain, pain in extremity, temporomandibular joint syndrome, arthralgia*** Renal and urinary disorders uncommon urinary hesitation, micturition urgency, pollakisuria
Estonian: aeg-ajalt lihasespasmid, ebamugavustunne jäsemetes, lihaste ja luustiku valu, kaelavalu, valu jäsemetes, temporomandibulaarliigese sündroom, artralgia***
English: • alcohol pad
Estonian: • alkoholis niisutatud lapp,
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each implant contains buprenorphine hydrochloride equivalent to 74.2 mg of buprenorphine.
Estonian: TOIMEAINE(TE) SISALDUS Üks implantaat sisaldab buprenorfiinvesinikkloriidi koguses, mis vastab 74,2 mg buprenorfiinile.
English: Respiratory, thoracic and mediastinal disorders common cough**, dyspnoea** uncommon respiratory depression, yawning Gastrointestinal disorders common constipation, nausea, vomiting, diarrhoea, abdominal pain, gastrointestinal disorder**, tooth disorder** uncommon dry mouth, dyspepsia, flatulence, haematochezia
Estonian: Seedetrakti häired sage kõhukinnisus, iiveldus, oksendamine, diarröa, kõhuvalu, seedetrakti häire**, hammaste kahjustused**
English: • muscle spasms, limb discomfort
Estonian: • lihasekrambid, ebamugavustunne jäsemetes
English: • pregnancy
Estonian: • Rasedus
English: • clarithromycin, erythromycin, troleandomycin: medicines to treat bacterial infections
Estonian: • bakteriaalsete infektsioonide raviks kasutatavad ravimeid klaritromütsiini, erütromütsiini, troleandomütsiin;
English: • migraine, tremor
Estonian: • peapööritus, unisus
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING Sachet
Estonian: SISEPAKENDIL PEAVAD OLEMA JÄRGMISED ANDMED Kotike
English: Cardiac disorders common palpitations** uncommon atrial flutter, bradycardia
Estonian: Südame häired sage palpitatsioon**
English: IMPORTANT INFORMATION Each implant contains buprenorphine hydrochloride equivalent to 74.2 mg of buprenorphine.
Estonian: Üks implantaat sisaldab sisaldab buprenorfiinvesinikkloriidi koguses, mis vastab 74,2 mg buprenorfiinile .