FrancophonIA/ELRC3.0 huggingface dataset:
English: This medicine blocks the tightening of these muscles in the lungs, making it easier for air to get in and out of the lungs.
Croatian: Ovaj lijek sprječava stezanje tih mišića u plućima te tako olakšava ulazak zraka u pluća i njegov izlazak iz pluća.
English: When you take the inhaler out of its tray, it will be in the ‘closed' position.
Croatian: Kad izvadite inhalator iz njegovog podloška, bit će u 'zatvorenom' položaju.
English: The other ingredients are lactose monohydrate (see section 2 under ‘ANORO ELLIPTA contains lactose') and magnesium stearate.
Croatian: Drugi sastojci su laktoza hidrat (vidjeti dio 2 pod „ANORO ELLIPTA sadrži laktozu“) i magnezijev stearat.
English: ANORO ELLIPTA should be administered at the same time of the day each day to maintain bronchodilation.
Croatian: ANORO ELLIPTA treba primjenjivati svakoga dana u isto vrijeme, kako bi se održao bronhodilatacijski učinak.
English: A population pharmacokinetic analysis showed that pharmacokinetics of umeclidinium and vilanterol were similar between COPD patients 65 years and older and those younger than 65 years of age.
Croatian: Populacijska farmakokinetička analiza pokazala je da su farmakokinetika umeklidinija i vilanterola bile slične u bolesnika s KOPB-om u dobi od 65 ili više godina i onih mlađih od 65 godina.
English: The results were similar to those for the ANORO ELLIPTA dose and provided additional supportive evidence for the efficacy of ANORO ELLIPTA.
Croatian: Rezultati su bili slični onima za dozu lijeka ANORO ELLIPTA te su pružili dodatne dokaze koji govore u prilog djelotvornosti lijeka ANORO ELLIPTA.
English: If you forget to use ANORO ELLIPTA Don't inhale an extra dose to make up for a forgotten dose.
Croatian: Ako ste zaboravili primijeniti ANORO ELLIPTA Nemojte inhalirati još jednu dozu kako biste nadoknadili zaboravljenu dozu.
English: The first time you use ANORO ELLIPTA you do not need to check that the inhaler is working properly; it contains previously measured doses and is ready to use straight away.
Croatian: Kada primjenjujete ANORO ELLIPTA po prvi puta, ne morate provjeravati radi li inhalator ispravno; on sadrži prethodno odmjerene doze i odmah je spreman za uporabu.
English: 55 micrograms/22 micrograms
Croatian: 55 mikrograma/22 mikrograma
English: If you think this applies to you, don't use this medicine until you have checked with your doctor.
Croatian: Ako mislite da se ovo odnosi na Vas, nemojte primijeniti lijek dok se ne posavjetujete sa svojim liječnikom.
English: It will only be effective as long as you are using it. Don't stop unless your doctor advises you to, even if you feel better, as your symptoms may get worse.
Croatian: Nemojte prestati primjenjivati lijek osim ako Vam to ne kaže liječnik, čak i ako se osjećate bolje, jer se simptomi mogu pogoršati.
English: Immediate breathing difficulties after using ANORO ELLIPTA are rare.
Croatian: Trenutne tegobe s disanjem nakon uzimanja lijeka ANORO ELLIPTA su rijetke.
English: • swelling, sometimes of the face or mouth (angioedema)
Croatian: • oticanje, katkad lica ili usana (angioedem)
English: Step-by-step instructions What is the inhaler?
Croatian: Upute korak po korak Što je inhalator?
English: Summary of the safety profile The most frequently reported adverse reaction with umeclidinium/vilanterol was nasopharyngitis (9%).
Croatian: Sažetak sigurnosnog profila Najčešće prijavljena nuspojava kod primjene umeklidinija/vilanterola bio je nazofaringitis (9%).
English: A decision must be made whether to discontinue breast-feeding or to discontinue umeclidinium/vilanterol therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Croatian: Potrebno je odlučiti da li prekinuti dojenje ili prekinuti liječenje umeklidinijem/vilanterolom uzimajući u obzir korist dojenja za dijete i korist liječenja za ženu.
English: There was no attenuation of the bronchodilator effect over time.
Croatian: Bronhodilatacijski učinak nije s vremenom oslabio.
English: EU/1/14/898/001 1 inhaler of 7 doses EU/1/14/898/002 1 inhaler of 30 doses
Croatian: EU/1/14/898/001 1 inhalator sa 7 doza EU/1/14/898/002 1 inhalator s 30 doza
English: The European Medicines Agency has waived the obligation to submit the results of studies with ANORO ELLIPTA in all subsets of the paediatric population in COPD (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove izuzela je obvezu podnošenja rezultata ispitivanja lijeka ANORO ELLIPTA u svim podskupinama pedijatrijske populacije u KOPB-u (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Don't use ANORO ELLIPTA if you already use these medicines.
Croatian: Nemojte koristiti ANORO ELLIPTA ako već primjenjujete navedene lijekove.
English: ∗ A step-down statistical testing procedure was used in this study and this comparison was below a comparison that did not achieve statistical significance.
Croatian: (tzv. step-down), a ova je usporedba bila niža od usporedbe koja nije postigla statističku značajnost.
English: Uncommon side effects (may affect up to 1 in 100 people): • skin rash (hives) or redness
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na 100 osoba): • kožni osip (koprivnjača) ili crvenilo kože
English: Contents of the pack and other information What ANORO ELLIPTA contains
Croatian: Sadržaj pakiranja i druge informacije Što ANORO ELLIPTA sadrži
English: A dose-dependent increase in heart rate was also observed.
Croatian: Opaženo je i o dozi ovisno povećanje srčane frekvencije.
English: The desiccant sachet should be thrown away and it should not be opened, eaten or inhaled.
Croatian: Vrećicu sa sredstvom za sušenje treba baciti; njezin se sadržaj ne smije otvoriti, pojesti ili inhalirati.
English: This leaflet was last revised in
Croatian: Ova uputa je zadnji puta revidirana u Drugi izvori informacija
English: Umeclidinium/vilanterol has no or negligible influence on the ability to drive and use machines.
Croatian: Umeklidinij/vilanterol ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: If you do not have a quick-acting inhaler contact your doctor.
Croatian: Ako nemate brzodjelujući inhalacijski lijek obratite se svom liječniku.
English: If you are breastfeeding, you must check with your doctor before you use ANORO ELLIPTA.
Croatian: Ako dojite, morate se obratiti svom liječniku prije nego uzmete ANORO ELLIPTA.
English: A population pharmacokinetic analysis showed that no dose adjustment is required for umeclidinium or vilanterol based on the effect of age, race, gender, inhaled corticosteroid use, or weight.
Croatian: Populacijska farmakokinetička analiza pokazala je da nije potrebno prilagođavati dozu umeklidinija ni vilanterola na temelju učinaka dobi, rase, spola, primjene inhalacijskih kortikosteroida ili tjelesne težine.
English: The active substances are present as a white powder in separate blisters inside the inhaler.
Croatian: Djelatne tvari dolaze u oblik bijeloga praška u zasebnim blisterima unutar inhalatora.
English: The safety profile of ANORO ELLIPTA is based on safety experience with umeclidinium/vilanterol and the individual components from the clinical development program comprising of 6,855 patients with COPD and from spontaneous reporting.
Croatian: Sigurnosni profil lijeka ANORO ELLIPTA temelji se na iskustvu povezanom sa sigurnošću primjene umeklidinija/vilanterola i njegovih pojedinačnih sastavnica u kliničkom razvojnom programu kojim je obuhvaćeno 6855 bolesnika s KOPB-om i iz spontanih prijava.
English: The ELLIPTA inhaler contains pre-dispensed doses and is ready to use.
Croatian: ELLIPTA inhalator sadrži odmjerene doze i spreman je za uporabu.
English: It is unlikely that ANORO ELLIPTA will affect your ability to drive or use machines.
Croatian: Nije vjerojatno da bi ANORO ELLIPTA mogao utjecati na sposobnost upravljanja vozilima i rada sa strojevima.
English: Antimuscarinic activity
Croatian: Antimuskarinsko djelovanje
English: It is a quinuclidine derivative with activity across multiple muscarinic receptor subtypes.
Croatian: To je kinuklidinski derivat koji djeluje na niz različitih podvrsta muskarinskih receptora.
English: GlaxoSmithKline (Ireland) Limited, 12 Riverwalk, Citywest Business Campus, Dublin 24, Ireland GlaxoSmithKline (Ireland) Limited logo
Croatian: GlaxoSmithKline (Ireland) Limited, 12 Riverwalk, Citywest Business Campus, Dublin 24, Irska GlaxoSmithKline (Ireland) Limited logo
English: There was no evidence for tachyphylaxis in the effect of ANORO ELLIPTA over time.
Croatian: Nije bilo znakova tahifilaksije na učinke lijeka ANORO ELLIPTA tijekom vremena.
English: 2 years In-use shelf-life after opening the tray: 6 weeks
Croatian: 2 godine Rok valjanosti nakon otvaranja podloška: 6 tjedana
English: Verapamil, a moderate CYP3A4 inhibitor, did not significantly affect the pharmacokinetics of vilanterol.
Croatian: Verapamil, umjereni inhibitor CYP3A4, nije značajno utjecao na farmakokinetiku vilanterola.
English: Medicinal products containing beta-adrenergic blockers may weaken or antagonise the effect of beta2-adrenergic agonists, such as vilanterol.
Croatian: Lijekovi koji sadrže blokatore beta-adrenergičkih receptora mogu oslabiti ili antagonizirati učinke beta2-adrenergičkih agonista, poput vilanterola.
English: Concomitant administration of strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, itraconazole, ritonavir, telithromycin) may inhibit the metabolism of, and increase the systemic exposure to, vilanterol.
Croatian: Istodobna primjena snažnih inhibitora CYP3A4 (npr. ketokonazola, klaritromicina, itrakonazola, ritonavira, telitromicina) može inhibirati metabolizam vilanterola i tako povećati sistemsku izloženost vilanterolu.
English: Studies in animals have shown reproductive toxicity at exposures which are not clinically relevant after administration of vilanterol (see section 5.3).
Croatian: Ispitivanja na životinjama pokazala su reproduktivnu toksičnost nakon primjene vilanterola, pri razinama izloženosti koje nisu klinički značajne (vidjeti dio 5.3).
English: Both umeclidinium and vilanterol are substrates of the P-glycoprotein transporter (P-gp).
Croatian: Umeklidinij i vilanterol su oboje supstrati za prijenosnik P-glikoprotein (P-gp).
English: The frequencies assigned to the adverse reactions identified in the table below include crude incidence rates observed in the integration of five 24-week studies and in the 12-month safety study.
Croatian: Učestalosti dodijeljene nuspojavama navedenima u tablici obuhvaćaju grube stope incidencije primijećene nakon objedinjavanja podataka iz pet 24-tjednih ispitivanja i 12-mjesečnog ispitivanja sigurnosti.
English: Care is advised when co-administering umeclidinium/vilanterol with ketoconazole and other known strong CYP3A4 inhibitors as there is potential for an increased systemic exposure to vilanterol, which could lead to an increase in the potential for adverse reactions.
Croatian: Preporučuje se oprez pri istodobnoj primjeni umeklidinija/vilanterola s ketokonazolom i drugim poznatim snažnim inhibitorima CYP3A4 jer postoji mogućnost povećane sistemske izloženosti vilanterolu, koja bi mogla povećati potencijal nastanka nuspojava.
English: If the dose counter does not count down as the “click” is heard, the inhaler will not deliver a dose and should be taken back to a pharmacist for advice.
Croatian: Ako se broj na brojaču doza ne smanji za 1 kada čujete ''klik'', inhalator neće isporučiti dozu i trebate ga vratiti ljekarniku i zatražiti savjet.
English: The pharmacologic effects of beta2-adrenergic agonists, including vilanterol, are at least in part attributable to stimulation of intracellular adenylate cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP).
Croatian: Farmakološki učinci agonista beta2-adrenergičkih agonista, uključujući vilanterol, barem se djelomično mogu pripisati stimulaciji unutarstanične adenilat ciklaze, enzima koji katalizira pretvorbu adenozin trifosfata (ATP) u ciklički-3',5'-adenozin monofosfat (ciklički AMP).
English: If you use more ANORO ELLIPTA than you should
Croatian: Ako primijenite više lijeka ANORO ELLIPTA nego što ste trebali
English: What ANORO ELLIPTA looks like and contents of the pack
Croatian: Kako ANORO ELLIPTA izgleda i sadržaj pakiranja
English: It is not known whether the ingredients of ANORO ELLIPTA can pass into breast milk.
Croatian: Nije poznato mogu li se sastojci lijeka ANORO ELLIPTA izlučiti u majčino mlijeko.
English: Following oral administration to healthy male volunteers, total radioactivity was excreted primarily in faeces (92% of the administered radiolabelled dose or 99% of the recovered radioactivity) by 168 hours post-dose.
Croatian: Nakon peroralne primjene u zdravih muških dobrovoljaca, ukupna radioaktivnost prvenstveno se izlučila fecesom (92% primijenjene radioaktivno označene doze ili 99% pronađene radioaktivnosti) unutar 168 sati nakon primjene doze.
English: • infection of the upper airways.
Croatian: • infekcija gornjih dišnih putova.
English: Improvements in TDI focal score compared with each monotherapy component and tiotropium were not statistically significant (see Table 1).
Croatian: Poboljšanja ukupnog TDI rezultata u usporedbi s primjenom svake od sastavnica u monoterapiji i tiotropijem nisu bila statistički značajna (vidjeti Tablicu 1).
English: Submission of the final clinical study report on a Post-Authorisation Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients with Anoro Ellipta compared with tiotropium (study 201038), according to a protocol agreed by the PRAC.
Croatian: Podnijeti završno izvješće o kliničkom ispitivanju za opservacijsko kohortno ispitivanje sigurnosti primjene nakon dobivanja odobrenja, koje ima za cilj kvantificirati incidenciju i usporediti sigurnost s obzirom na odabrane kardiovaskularne i cerebrovaskularne događaje u bolesnika s KOPB-om kod primjene lijeka Anoro Ellipta u usporedbi s tiotropijem (ispitivanje 201038), prema protokolu dogovorenom od strane Povjerenstva za ocjenu rizika na području farmakovigilancije.
English: Other medicines and ANORO ELLIPTA
Croatian: Drugi lijekovi i ANORO ELLIPTA
English: Less than 1% of the orally administered dose (1% of recovered radioactivity) was excreted in urine, suggesting negligible absorption following oral administration.
Croatian: Manje od 1% peroralno primijenjene doze (1% pronađene radioaktivnosti) izlučilo se mokraćom, što ukazuje na zanemarivu apsorpciju nakon peroralne primjene.
English: Keep the inhaler inside the sealed tray in order to protect from moisture and only remove immediately before first use.
Croatian: Čuvati inhalator u zatvorenom podlošku radi zaštite od vlage i otvarati ga tek neposredno prije prve uporabe.
English: If your COPD symptoms (breathlessness, wheezing, cough) do not improve or get worse, or if you are using your quick-acting inhaler more often:
Croatian: Ako Vam se simptomi KOPB-a (nedostatak zraka, piskanje pri disanju, kašalj) ne poboljšaju ili se pogoršaju, ili ako primjenjujete brzodjelujući inhalacijski lijek češće nego inače: obratite se svom liječniku što je prije moguće.
English: In nonclinical studies with umeclidinium and vilanterol, alone and in combination, findings were those typically associated with the primary pharmacology of either muscarinic receptor antagonists or beta2-adrenergic agonists respectively and/or local irritancy.
Croatian: U nekliničkim ispitivanjima s umeklidinijem i vilanterolom, samostalno i u kombinaciji, rezultati su bili jednaki onima koji se tipično povezuju s primarnom farmakologijom antagonista muskarinskih receptora ili beta2-adrenergičkih agonista i/ili lokalnom iritacijom.
English: Following intravenous administration to healthy volunteers, the mean volume of distribution was 86 litres.
Croatian: Nakon intravenske primjene u zdravih dobrovoljaca, srednja vrijednost volumena distribucije iznosila je 86 litara.
English: Following repeat dosing of inhaled vilanterol, steady state was achieved within 6 days with up to 2.4-fold accumulation.
Croatian: Nakon inhalacije ponovljenih doza vilanterola, stanje dinamičke ravnoteže postignuto je unutar 6 dana, a kumulacija se povećala za 2,4 puta.
English: In vitro plasma protein binding in human plasma was on average 94%.
Croatian: Vezanje za proteine u plazmi ljudi in vitro u prosjeku je iznosilo 94%.
English: Lung function, symptomatic and health related quality of life outcomes at Week 24 Treatment comparisons with ANORO
Croatian: Ishodi povezani s plućnom funkcijom, simptomima i kvalitetom života vezanom uz zdravlje nakon 24 tjedna Usporedba u odnosu na liječenje lijekom
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before using this medicine.
Croatian: Ako Vam je liječnik rekao da ne podnosite neke šećere, obratite se liječniku prije primjene ovog lijeka.
English: A study in CYP2D6 poor metabolisers showed no evidence of a clinically significant effect of CYP2D6 genetic polymorphism on systemic exposure to umeclidinium.
Croatian: U ispitivanju sa slabim metabolizatorima CYP2D6 nisu pronađeni dokazi klinički značajnog učinka genetskog polimorfizma CYP2D6 na sistemsku izloženost umeklidiniju.
English: • difficulty and pain when passing urine - these may be signs of a bladder obstruction or urinary retention.
Croatian: • poteškoće i bol prilikom mokrenja-ovo mogu biti znakovi opstrukcije mjehura ili zadržavanja mokraće.
English: When umeclidinium and vilanterol were administered in combination by the inhaled route, the pharmacokinetics of each component was similar to those observed when each active substance was administered separately.
Croatian: Kada su se umeklidinij i vilanterol primjenjivali zajedno inhalacijom, farmakokinetika tih dvaju sastavnica bila je slična onoj opaženoj kod primjene svake od dviju djelatnih tvari zasebno.
English: Umeclidinium/vilanterol should not be used in patients with asthma since it has not been studied in this patient population.
Croatian: Umeklidinij/vilanterol se ne smije primjenjivati u bolesnika s astmom jer lijek nije ispitivan u toj populaciji bolesnika.
English: In the other two active-comparator studies, a similar proportion of patients achieved at least the MCID with ANORO ELLIPTA and tiotropium; 49% and 54% for ANORO ELLIPTA 55/22 micrograms and 52% and 55% for tiotropium.
Croatian: U druga dva ispitivanja s aktivnim usporednim lijekom sličan je udio bolesnika postigao barem MCID i uz primjenu lijeka ANORO ELLIPTA i uz primjenu tiotropija; 49% i 54% uz ANORO ELLIPTA od 55/22 mikrograma te 52% i 55% uz tiotropij.
English: Umeclidinium is a long acting muscarinic receptor antagonist (also referred to as an anticholinergic).
Croatian: Umeklidinij je dugodjelujući antagonist muskarinskih receptora (naziva se još i antikolinergikom).
English: • becoming very wheezy, coughing or having difficulty in breathing
Croatian: • jako piskanje pri disanju, kašalj ili imate teškoće s disanjem
English: In the event of deterioration of COPD during treatment with umeclidinium/vilanterol, a re-evaluation of the patient and of the COPD treatment regimen should be undertaken.
Croatian: U slučaju pogoršanja KOPB-a tijekom liječenja umeklidinijem/vilanterolom, treba ponovno procijeniti stanje bolesnika i režim liječenja KOPB-a.
English: (<1/10,000) and not known (cannot be estimated from available data).
Croatian: (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000) i nepoznato (ne može se procijeniti iz dostupnih podataka).
English: medicines called beta blockers (such as propranolol), to treat high blood pressure or other heart problems ketoconazole or itraconazole, to treat fungal infections clarithromycin or telithromycin, to treat bacterial infections ritonavir, to treat HIV infection medicines that lower the amount of potassium in your blood, such as some diuretics (water tablets) or some medicines used to treat asthma (such as methylxanthine or steroids) other long-acting medicines similar to this medicine that are used to treat breathing problems, e.g. tiotropium, indacaterol.
Croatian: lijekove koji se zovu beta blokatori (poput propranolola), a koriste se za liječenje visokog krvnog tlaka ili drugih srčanih tegoba ketokonazol ili itrakonazol, koji se koriste za liječenje gljivičnih infekcija klaritromicin ili telitromicin, koji se koriste za liječenje bakterijskih infekcija ritonavir, koji se koristi za liječenje HIV infekcije lijekove koji smanjuju količinu kalija u krvi, poput nekih diuretika (tableta za izmokravanje viška tekućine iz tijela) ili neke lijekove koji se koriste za liječenje astme (kao što su metilksantin ili steroidi)
English: Beta2-adrenergic agonists may produce significant hypokalaemia in some patients, which has the potential to produce adverse cardiovascular effects.
Croatian: Beta2-adrenergički agonisti mogu u nekih bolesnika izazvati značajnu hipokalijemiju, koja može uzrokovati kardiovaskularne nuspojave.
English: ANORO ELLIPTA contains two active substances umeclidinium bromide and vilanterol.
Croatian: ANORO ELLIPTA sadrži dvije djelatne tvari, umeklidinij bromid i vilanterol.
English: Use ANORO ELLIPTA regularly
Croatian: Primjenjujte ANORO ELLIPTA redovito
English: 1 inhaler of 7 doses 1 inhaler of 30 doses
Croatian: 1 inhalator sa 7 doza 1 inhalator s 30 doza
English: The inhaler contains two aluminium foil laminate blisters of 7 or 30 doses.
Croatian: Inhalator sadrži dva blistera od višeslojne aluminijske folije sa 7 ili 30 doza.
English: Administration of umeclidinium/vilanterol may produce paradoxical bronchospasm that may be lifethreatening.
Croatian: Paradoksalni bronhospazam Primjena umeklidinija/vilanterola može uzrokovati paradoksalni bronhospazam, koji može biti opasan po život.
English: In the second study, the treatment difference in EET between ANORO ELLIPTA 55/22 micrograms and placebo was 21.9 seconds (p=0.234) at Week 12.
Croatian: U drugom je ispitivanju terapijska razlika EET vrijednosti između lijeka ANORO ELLIPTA od 55/22 mikrograma i placeba iznosila 21,9 sekundi (p=0,234) nakon 12 tjedana.
English: • combination of sore throat and runny nose
Croatian: • kombinacija grlobolje i curenja iz nosa
English: ANORO ELLIPTA is used to treat chronic obstructive pulmonary disease (COPD) in adults.
Croatian: ANORO ELLIPTA se koristi za liječenje kronične opstruktivne plućne bolesti (KOPB) u odraslih osoba.
English: Following inhaled administration of vilanterol in healthy volunteers, Cmax occurred at 5 to 15 minutes.
Croatian: Nakon inhalacijske primjene vilanterola u zdravih dobrovoljaca, Cmax je dosegnut nakon 5 do 15 minuta.
English: Urinary elimination accounted for 22% of the administered radiolabelled dose by 168 hours (27% of recovered radioactivity).
Croatian: Mokraćom se izlučilo 22% primijenjene radioaktivno označene doze i to unutar 168 sati (27% pronađene radioaktivnosti).
English: Following oral inhalation both compounds act locally on airways to produce bronchodilation by separate mechanisms.
Croatian: Nakon peroralne inhalacije, oba spoja djeluju lokalno u dišnim putovima i zasebnim mehanizmima djelovanja uzrokuju bronhodilataciju.
English: An approximately 1.4-fold increase in umeclidinium AUC was observed with no effect on vilanterol AUC.
Croatian: Primijećeno je povećanje AUC-a umeklidinija za oko 1,4 puta, dok na AUC vilanterola nije bilo učinka.
English: ANORO ELLIPTA also demonstrated a greater increase from baseline in the proportion of days when no rescue medication was needed in all three studies (average within the range 17.6% to 21.5%) compared with tiotropium (average within the range 11.7% to 13.4%).
Croatian: ANORO ELLIPTA je u sva tri ispitivanja pokazao značajnije proporcionalno povećanje u danima, naspram početne vrijednosti kada nije bila potrebna primjena lijeka za hitno ublažavanje simptoma (prosjek u rasponu od 17,6% do 21,5%) u usporedbi s tiotropijem (prosjek u rasponu od 11,7% do 13,4%).