FrancophonIA/ELRC3.0 huggingface dataset:
English: Kymriah is a type of advanced therapy medicine called a ‘gene therapy product'.
Slovenian: Zdravilo Kymriah spada v skupino zdravil za napredno zdravljenje, ki se imenujejo „zdravila za gensko zdravljenje“.
English: Kymriah is prepared using the patient's own white blood cells which are extracted from the blood and genetically modified in the laboratory.
Slovenian: Zdravilo Kymriah se pripravi z uporabo bolnikovih lastnih belih krvnih celic, ki se pridobijo iz krvi in v laboratoriju gensko spremenijo.
English: How is Kymriah used?
Slovenian: Kako se zdravilo Kymriah uporablja?
English: B-cell ALL patients have poor outcomes and improvements with Kymriah were better than with other medicines for this condition.
Slovenian: Izidi pri bolnikih z B-celično akutno limfoblastno levkemijo so slabi, izboljšanje pri zdravljenju z zdravilom Kymriah pa je preseglo izboljšanje pri zdravljenju te bolezni z drugimi zdravili.
English: • B-cell acute lymphoblastic leukaemia (ALL), in children and young adults up to 25 years of age whose cancer did not respond to previous treatment, has come back two or more times, or has come back after a transplant of stem cells;
Slovenian: • B-celične akutne limfoblastne levkemije pri otrocih in mladih odraslih, starih do 25 let, pri katerih se rak ni odzval na predhodno zdravljenje, se je dvakrat ali večkrat ponovil ali pa se je ponovil po presaditvi matičnih celic;
English: The blood cancers that Kymriah is used to treat are rare, and Kymriah was designated an ‘orphan medicine' (a medicine used in rare diseases) for B-cell ALL on 29 April 2014 and DLBCL on 14 October
Slovenian: Vrsti krvnega raka, za zdravljenje katerih se uporablja zdravilo Kymriah, sta redki, zato je bilo zdravilo Kymriah 29. aprila 2014 določeno kot „zdravilo sirota“ (zdravilo za zdravljenje redkih boleznih) za zdravljenje B-celične akutne limfoblastne levkemije in 14. oktobra 2016 kot „zdravilo sirota“ za zdravljenje difuznega velikoceličnega B-limfoma.
English: For the full list of side effects and restrictions with Kymriah, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov in omejitev pri uporabi zdravila Kymriah glejte navodilo za uporabo.
English: • Diffuse large B-cell lymphoma (DLBCL) in adults whose cancer has come back or did not respond after two or more previous treatments.
Slovenian: • difuznega velikoceličnega B-limfoma pri odraslih, pri katerih se je rak ponovil ali pa se ni odzval po dveh ali več predhodnih zdravljenjih.
English: Kymriah contains the active substance tisagenlecleucel (consisting of genetically modified white blood cells).
Slovenian: Zdravilo Kymriah vsebuje učinkovino tisagenlecleucel (sestavljeno iz gensko spremenjenih belih krvnih celic).
English: Tocilizumab must be available in case of cytokine release syndrome.
Slovenian: Za primer sindroma sproščanja citokinov mora biti na voljo tocilizumab.
English: It is given as a single infusion (drip) into a vein and must only be given to the patient whose cells were used to make it. Before having Kymriah, the patient should have a short course of chemotherapy to clear away their white blood cells and just before the infusion, they are given paracetamol and an antihistamine medicine to reduce the risk of reactions to the infusion.
Slovenian: Pred uporabo zdravila Kymriah je treba bolnika kratkotrajno zdraviti s kemoterapijo, da se odstranijo bele krvne celice, tik pred infuzijo pa bolnik prejme paracetamol in antihistaminik za zmanjšanje tveganja reakcije na infuzijo.
English: The main study of Kymriah in B-cell ALL involved 92 children and young adults (3-25 years of age) whose cancer had come back after previous treatment or did not respond to treatment.
Slovenian: V glavno študijo uporabe zdravila Kymriah pri zdravljenju B-celične akutne limfoblastne levkemije je bilo vključenih 92 otrok in mladih odraslih (starih od treh do 25 let), pri katerih se je rak ponovil po predhodnem zdravljenju ali se ni odzval na zdravljenje.
English: The main study of Kymriah in DLBCL involved 165 patients who had at least 2 previous treatments and could not have a stem cell transplant.
Slovenian: V glavno študijo uporabe zdravila Kymriah pri zdravljenju difuznega velikoceličnega B-limfoma je bilo vključenih 165 bolnikov, ki so se pred tem že vsaj dvakrat zdravili in niso mogli prejeti presadka matičnih celic.
English: How does Kymriah work?
Slovenian: Kako zdravilo Kymriah deluje?
English: Serious infections occur in around 3 in 10 DLBCL patients.
Slovenian: Pri približno treh bolnikih z difuznim velikoceličnim B-limfomom od 10 je prišlo do resne okužbe.
English: B-cell ALL
Slovenian: Difuzni velikocelični B-limfom
English: Serious side effects, occur in most patients, and can include cytokine release syndrome.
Slovenian: Resni neželeni učinki se pojavijo pri večini bolnikov in lahko vključujejo sindrom sproščanja citokinov, vendar pa so ti učinki ob primernih ukrepih (glejte v nadaljevanju) obvladljivi.
English: (Invented)name Strength Pharmaceutical form
Slovenian: (Izmišljeno) ime Jakost Farmacevtska oblika
English: • Contamination and/or infection,
Slovenian: • onesnaženje in/ali okužbo,
English: Elderly population (≥65 years old)
Slovenian: Starejša populacija (≥65 let)
English: No new safety signals were observed in this study.
Slovenian: V tej študiji niso odkrili nobenih novih varnostnih signalov.
English: The following graph shows the results from a study in patients:
Slovenian: Spodnji graf prikazuje rezultate študije pri bolnikih:
English: The safety and efficacy of Lantus have not been established.
Slovenian: Varnost in učinkovitost zdravila Lantus nista raziskani.
English: Store in a refrigerator (2°C-8°C).
Slovenian: Shranjujte v hladilniku (2°C - 8°C).
English: Other source of information
Slovenian: Drugi viri informacij
English: Avoid situations where SoloStar might be damaged.
Slovenian: Izogibajte se okoliščinam, v katerih se SoloStar lahko poškoduje.
English: Date of first use:……………
Slovenian: EXP Datum prve uporabe: ...............
English: Date of first authorisation: 9 June 2000 Date of latest renewal: 17 February 2015
Slovenian: Datum zadnjega podaljšanja: 17. februar 2015
English: It should be handled with care.
Slovenian: Z njim morate ravnati previdno.
English: Low blood sugar means that there is not enough sugar in your blood.
Slovenian: Nizek krvni sladkor pomeni, da v vaši krvi ni dovolj sladkorja.
English: Both groups received bolus insulin before meals.
Slovenian: V obeh skupinah so pred obroki prejeli bolus insulina.
English: Do not use this SoloStar.
Slovenian: Ne uporabljajte tega SoloStarja.
English: You need one injection of Lantus every day, at the same time of the day.
Slovenian: Vsak dan potrebujete eno injekcijo zdravila Lantus ob istem času dneva.
English: This may constitute a risk in situations where these abilities are of special importance (e.g. driving a car or using machines).
Slovenian: To je lahko nevarno v okoliščinah, v katerih sta ti zmožnosti posebno pomembni (npr. pri vožnji avtomobila ali upravljanju s stroji).
English: Most minor reactions to insulins usually disappear in a few days to a few weeks.
Slovenian: Večina manjših reakcij na insuline ponavadi izgine v nekaj dneh do nekaj tednih.
English: Your doctor will show you in which area of the skin you should inject Lantus.
Slovenian: Zdravnik vam bo pokazal, v kateri predel kože injicirajte zdravilo Lantus.
English: • Children below 2 years of age
Slovenian: • Otroci, mlajši od 2 let
English: Do NOT inject Lantus in a vein, since this will change its action and may cause hypoglycaemia.
Slovenian: Zdravila Lantus NE injicirajte v veno, ker to spremeni njegovo delovanje in lahko povzroči hipoglikemijo.
English: Please, consult your doctor for further information.
Slovenian: Za dodatne informacije se posvetujte z zdravnikom.
English: • If no insulin comes out, check for air bubbles and repeat the safety test two more times to remove them.
Slovenian: • Če se insulin ne pokaže, poglejte, ali so v vložku zračni mehurčki, in varnostni test še dvakrat ponovite, da jih boste odstranili.
English: Lantus should be administered once daily at any time but at the same time each day.
Slovenian: Zdravilo Lantus je treba aplicirati enkrat na dan, in sicer kadarkoli, vendar vsak dan ob istem času.
English: Fertility Animal studies do not indicate direct harmful effects with respect to fertility.
Slovenian: Študije na živalih ne kažejo neposrednih škodljivih učinkov na plodnost.
English: Since Lantus is a solution, it does not require resuspension before use.
Slovenian: Ker je zdravilo Lantus raztopina, pred uporabo ne potrebuje resuspendiranja.
English: The marketing authorisation holder shall submit periodic safety update reports for this product in accordance with the requirements set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and published on the European medicines web-portal.
Slovenian: • Redno posodobljena poročila o varnosti zdravila (PSUR) Imetnik dovoljenja za promet z zdravilom mora redno posodobljena poročila o varnosti zdravila za to zdravilo predložiti v skladu z zahtevami, določenimi v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES in objavljen na evropskem spletnem portalu o zdravilih.
English: Caution: Artificial sweeteners and foods with artificial sweeteners (such as diet drinks) are of no help in treating hypoglycaemia.
Slovenian: Pozor: Umetna sladila in hrana z umetnimi sladili (kot so dietne pijače) pri zdravljenju hipoglikemije ne pomagajo.
English: The following related adverse reactions from clinical investigations are listed below by system organ class and in order of decreasing incidence (very common: ≥1/10; common: ≥1/100 to <1/10; uncommon: ≥1/1,000 to <1/100; rare: ≥1/10,000 to <1/1,000; very rare: <1/10,000).
Slovenian: Naslednji povezani neželeni učinki, ugotovljeni v kliničnih raziskavah, so navedeni spodaj po organskih sistemih in razvrščeni po padajoči incidenci (zelo pogosti: ≥1/10; pogosti: ≥1/100 do <1/10; občasni: ≥1/1.000 do <1/100; redki: ≥1/10.000 do <1/1.000; zelo redki: <1/10.000).
English: Do not shake or mix it before use.
Slovenian: Pred uporabo ga ne tresite ali mešajte.
English: This pen is only for your use.
Slovenian: Ta peresnik je namenjen le za vašo uporabo.
English: -In your body
Slovenian: V vašem telesu
English: • Always perform the safety test before each injection (see Step 3).
Slovenian: • Pred vsakim injiciranjem opravite varnostni preizkus (glejte Korak 3).
English: The switch from one insulin therapy to another requires medical prescription, medical supervision and blood glucose monitoring.
Slovenian: Prehod z enega insulina na drugega zahteva zdravniški recept, zdravniški nadzor in kontroliranje glukoze v krvi.
English: Activity profile in patients with type 1 diabetes
Slovenian: Potek delovanja pri bolnikih z diabetesom tipa 1
English: Other medicines and Lantus
Slovenian: Druga zdravila in zdravilo Lantus
English: This should be kept in mind if treatment with the combination of pioglitazone and Lantus is considered.
Slovenian: To je potrebno upoštevati pri zdravljenju s kombinacijo pioglitazona in zdravila Lantus.
English: The dose regimen (dose and timing) should be individually adjusted.
Slovenian: Odmerjanje (odmerek in čas apliciranja) mora biti prilagojeno individualno.
English: Secondary endpoints included all-cause mortality and a composite microvascular outcome.
Slovenian: Med sekundarnimi opazovanimi dogodki so bili umrljivost zaradi vseh vzrokov in sestavljeni mikrovaskularni izid.
English: *determined as amount of glucose infused to maintain constant plasma glucose levels (hourly mean values)
Slovenian: *določena kot količina infundirane glukoze, potrebna za vzdrževanje stalne koncentracije glukoze v plazmi (povprečne urne vrednosti)
English: Zinc chloride
Slovenian: Cinkov klorid
English: • Entry of air into the insulin reservoir and leakage of insulin, which can cause inaccurate dosing.
Slovenian: • vstopanje zraka v rezervoar z insulinom in iztekanje insulina, ki lahko povzročita netočno odmerjanje.
English: The use of Lantus may be considered during pregnancy, if clinically needed.
Slovenian: Uporabo zdravila Lantus med nosečnostjo je treba presoditi, če je le-ta klinično potrebna.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Slovenian: Imetnik dovoljenja za promet z zdravilom bo izvede zahtevane farmakovigilančne aktivnosti in ukrepe, podrobno opisane v sprejetem RMP, predloženemu v modulu 1.8.2 dovoljenja za promet z zdravilom, in vseh nadaljnih sprejetih posodobitvah RMP.
English: This could lead to severe hyperglycaemia (very high blood sugar) and ketoacidosis (build-up of acid in the blood because the body is breaking down fat instead of sugar).
Slovenian: To lahko vodi v hudo hiperglikemijo (zelo visok krvni sladkor) in ketoacidozo (kopičenje kisline v krvi, ker telo presnavlja maščobe namesto sladkorja).
English: Lantus is not the insulin of choice for the treatment of diabetic ketoacidosis.
Slovenian: Zdravilo Lantus ni insulin prve izbire za zdravljenje diabetične ketoacidoze.
English: Hypoglycaemia (low blood sugar) can be very serious and is very common with insulin treatment (may affect more than 1 in 10 people).
Slovenian: Hipoglikemija (nizek krvni sladkor) je lahko zelo resna in je zelo pogosta pri terapiji z insulinom (pojavi se lahko pri več kot 1 od 10 bolnikov).
English: Opened vials, in-use cartridges or SoloStar pens For storage conditions after first opening of this medicinal product, see section 6.3.
Slovenian: Odprte viale, vložki, ki jih uporabljate ali SoloStar injekcijski peresniki Za pogoje shranjevanja po prvem odprtju zdravila, glejte poglavje 6.3.
English: Over the course of this 6-year study, 42% of the insulin glargine group did not experience any hypoglycaemia.
Slovenian: Med to 6-letno študijo 42 % skupine z insulinom glarginom ni imelo nobene hipoglikemije.
English: Clinical study safety data are not available for children under 2 years.
Slovenian: Kliničnih študij o varnosti pri otrocih, mlajših od 2 let, ni na voljo.
English: SoloStar has to be used as recommended in these instructions for use (see section 6.6).
Slovenian: SoloStar je treba uporabljati v skladu s priporočili v tem navodilu za uporabo (glejte poglavje 6.6).
English: In general, the safety profile for children and adolescents (≤18 years of age) is similar to the safety profile for adults.
Slovenian: Navadno je varnostni profil otrok in mladostnikov (starih 18 let), podoben varnostnemu profilu odraslih bolnikov
English: In use conditions:
Slovenian: Pogoji med uporabo:
English: Follow recommended safety measures for removal and disposal of needles (contact your doctor, pharmacist or nurse) in order to reduce the risk of accidental needle injury and transmission of infectious diseases.
Slovenian: Upoštevajte priporočene varnostne ukrepe, ko igle odstranjujete in zavržete (posvetujte se s svojim zdravnikom, s farmacevtom ali z medicinsko sestro), da boste zmanjšali tveganje za naključno poškodbo z iglo in prenos nalezljivih bolezni.
English: B. Line up the needle with the pen, and keep it straight as you attach it (screw or push on, depending on the needle type).
Slovenian: B. Naravnajte iglo z injekcijskim peresnikom in jo držite naravnost, medtem ko jo nameščate (privijte jo ali jo potisnite, odvisno od vrste igle).
English: Mixing or diluting can change its time/action profile and mixing can cause precipitation.
Slovenian: Mešanje ali redčenje lahko spremeni profil časovnega poteka in delovanje; mešanje lahko povzroči precipitacijo.
English: It is essential for patients with pre-existing or gestational diabetes to maintain good metabolic control throughout pregnancy to prevent adverse outcomes associated with hyperglycemia.
Slovenian: Nujno je, da bolnice z obstoječim ali gestacijskim diabetesom vso nosečnost vzdržujejo dobro urejenost presnove, da preprečijo neželene učinke, povezane s hiperglikemijo.
English: The plunger will reach the end of the cartridge when the total of 300 units of insulin has been used.
Slovenian: Bat bo v vložku dosegel konec, ko bo porabljenih vseh 300 enot insulina.
English: A. MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE
Slovenian: A. IZDELOVALEC BIOLOŠKE ZDRAVILNE UČINKOVINE IN IZDELOVALCI, ODGOVORNI ZA SPROŠČANJE SERIJ
English: These units are exclusive to Lantus and are not the same as IU or the units used to express the potency of other insulin analogues (see section 5.1).
Slovenian: Te enote veljajo izključno za zdravilo Lantus in niso enake mednarodnim enotam (i.e.) ali enotam, ki se uporabljajo za izražanje jakosti drugih insulinskih analogov (glejte poglavje 5.1).
English: Inspect Lantus before use.
Slovenian: Zdravilo Lantus pred uporabo preglejte.
English: Do not dilute it. Mixing or diluting may change the action of Lantus.
Slovenian: Ne redčite ga. Mešanje ali redčenje lahko spremeni delovanje zdravila Lantus.
English: Shelf-life after first use of the vial
Slovenian: Rok uporabnosti po prvi uporabi viale
English: If you are not confident about recognising your warning symptoms, avoid situations (such as driving a car) in which you or others would be put at risk by hypoglycaemia.
Slovenian: Če se ne morete povsem zanesti na prepoznavo svojih opozorilnih simptomov, se izogibajte okoliščinam (na primer vožnji avtomobila), v katerih bi zaradi hipoglikemije ogrožali sebe ali druge.
English: If you have any questions about SoloStar or about diabetes, ask your doctor, pharmacist or nurse or call the local representative number on the front of this leaflet.
Slovenian: Če imate kakšna vprašanja o injekcijskem peresniku SoloStar ali o sladkorni bolezni, vprašajte svojega zdravnika, farmacevta ali medicinsko sestro ali pokličite na lokalno telefonsko številko predstavništva, ki jo najdete na sprednji strani tega navodila.
English: Most minor reactions to insulins at the injection site usually resolve in a few days to a few weeks.
Slovenian: Večina manjših reakcij na insuline na mestu injiciranja ponavadi mine v nekaj dneh do nekaj tednih.
English: To reduce the risk of accidental needle injury, never replace the inner needle cap.
Slovenian: Da boste zmanjšali tveganje za naključno poškodbo z iglo, nikoli ne nameščajte nazaj notranjega pokrovčka igle.
English: Your doctor may tell you to use it in combination with a short-acting insulin or with tablets used to treat high blood sugar levels.
Slovenian: Zdravnik bo morda naročil, da ga uporabljajte v kombinaciji s kratkodelujočim insulinom ali s tabletami, ki se uporabljajo za zdravljanje visokega krvnega sladkorja.
English: Change the injection site with each injection to help prevent these skin changes.
Slovenian: Zamenjajte mesto injiciranja pri vsaki injekciji, da pomagate preprečiti takšne kožne spremembe.
English: TEXT TO APPEAR ON THE ALUMINIUM FOIL WHICH IS USED FOR SEALING TRANSPARENT PLASTIC TRAY CONTAINING THE CARTRIDGE
Slovenian: BESEDILO NATISNJENO NA ALUMINIJSKI FOLIJI, UPORABLJENI ZA ZAPRTJE PROSOJNEGA PLASTIČNEGA LEŽIŠČA, V KATEREM JE VLOŽEK
English: Keep this possible problem in mind in all situations where you might put yourself and others at risk (such as driving a car or using machines).
Slovenian: Ne pozabite na to v okoliščinah, v katerih bi lahko ogrozili sebe in druge (kot sta vožnja avtomobila ali upravljanje strojev).
English: Lantus with alcohol
Slovenian: Zdravilo Lantus skupaj z alkoholom
English: -In your brain
Slovenian: V vaših možganih
English: In patients with type 2 diabetes mellitus, Lantus can also be given together with orally active antidiabetic medicinal products.
Slovenian: Pri bolnikih z diabetesom mellitusom tipa 2 je mogoče zdravilo Lantus uporabljati tudi skupaj s peroralnimi antidiabetičnimi zdravili.
English: To ensure that you read the dose correctly, hold the pen horizontally, with the needle on the left and the dosage selector to the right as shown in the illustrations below.
Slovenian: Da boste zagotovo pravilno prebrali količino odmerka, držite injekcijski peresnik vodoravno, z injekcijsko iglo na levi in dozirnim rezervoarjem na desni, kot je prikazano na spodnji sliki.
English: • If the needle is not kept straight while you attach it, it can damage the rubber seal and cause leakage, or break the needle.
Slovenian: • Če igle med nameščanjem ne držite naravnost, lahko poškoduje gumijasto zaporo in povzroči iztekanje, ali pa se igla zlomi.
English: The first co-primary efficacy outcome was the time to the first occurrence of CV death, nonfatal myocardial infarction (MI), or nonfatal stroke, and the second co-primary efficacy outcome was the time to the first occurrence of any of the first co-primary events, or revascularisation procedure (coronary, carotid, or peripheral), or hospitalisation for heart failure.
Slovenian: Prvi soprimarni izid učinkovitosti je bil čas do prvega pojava KV smrti, miokardnega infarkta (MI) brez smrtnega izida ali možganske kapi brez smrtnega izida, sekundarni soprimarni izid učinkovitosti pa je bil čas do prvega pojava katerega koli prvega soprimarnega dogodka ali revaskularizacijskega posega (koronarnega, karotidnega ali perifernega) ali hospitalizacije zaradi srčnega popuščanja.
English: There were no differences between insulin glargine and standard care for the two co-primary outcomes; for any component endpoint comprising these outcomes; for all-cause mortality; or for the composite microvascular outcome.
Slovenian: Med insulinom glarginom in standardno oskrbo ni bilo razlik glede obeh soprimarnih izidov, glede nobene komponente opazovanega dogodka, ki je obsegal te izide, glede umrljivosti zaradi vseh vzrokov, ali glede sestavljenega mikrovaskularnega izida.
English: Unopened vials, unopened cartridges, not in-use SoloStar pens Store in a refrigerator (2°C-8°C).
Slovenian: Neodprte viale, neodprti vložki, neuporabljeni SoloStar injekcijski peresniki Shranjujte v hladilniku (2°C - 8°C).
English: Medication errors have been reported in which other insulins, particularly short-acting insulins, have been accidentally administered instead of insulin glargine.
Slovenian: O napakah zdravljenja so poročali, ko so bili drugi insulini, posebno kratko delujoči insulini, pomotoma aplicirani namesto insulina glargin.
English: In a randomised, controlled clinical study, paediatric patients (age range 6 to 15 years) with type 1 diabetes (n=349) were treated for 28 weeks with a basal-bolus insulin regimen where regular human insulin was used before each meal.
Slovenian: V randomizirani, kontrolirani klinični študiji so pediatrične bolnike (stare od 6 do 15 let) s sladkorno boleznijo tipa 1 (n=349) 28 tednov zdravili z bazalno-bolusnim insulinskim režimom, pri katerem je bil pred vsakim obrokom uporabljen navadni humani insulin.
English: If you inject your insulin too often at the same skin site, fatty tissue under the skin at this site may either shrink (lipoatrophy, may affect up to 1 in 100 people) or thicken (lipohypertrophy).
Slovenian: Če si insulin prepogosto injicirate na istem mestu kože, se lahko podkožno maščevje na tem mestu bodisi skrči (lipoatrofija, pojavi se lahko pri največ 1 od 100 bolnikov) ali zadebeli (lipohipertrofija).
English: Insulin glargine did not alter the relative risk for CV disease and CV mortality when compared to standard of care.
Slovenian: Insulin glargin v primerjavi s standardno oskrbo ni spremenil relativega tveganja za KV bolezen ali KV umrljivost.
English: Important information about some of the ingredients of Lantus
Slovenian: Pomembne informacije o nekaterih sestavinah zdravila Lantus
English: At baseline, participants had a median HbA1c value of 6.4% and median on-treatment HbA1c values ranged from 5.9 to 6.4% in the insulin glargine group, and 6.2% to 6.6% in the standard care group throughout the duration of follow-up.
Slovenian: Izhodiščno so imeli preiskovanci mediano vrednost HbA1c 6,4 %; mediana vrednost HbA1c med zdravljenjem je segala od 5,9 do 6,4 % v skupini z insulinom glarginom in od 6,2 % do 6,6 % v skupini s standardno oskrbo med celotnim trajanjem spremljanja.