FrancophonIA/ELRC3.0 huggingface dataset:
English: Do not give Viekirax to children and adolescents under 18 years of age.
Danish: Giv ikke Viekirax til børn og unge under 18 år.
English: While no change to the pharmacokinetics of warfarin is expected, close monitoring of INR is recommended with all vitamin K antagonists.
Danish: Selvom der ikke forventes ændringer af warfarins farmakokinetik, anbefales tæt monitorering af INR sammen med alle vitamin K-antagonister.
English: Your doctor will talk with you about which of these medicines to take with Viekirax.
Danish: Din læge vil tale med dig om, hvilket af disse lægemidler du skal tage sammen med Viekirax.
English: Concomitant use of fluticasone can increase systemic exposures of fluticasone.
Danish: Samtidig brug af fluticason kan øge den systemiske eksponering af fluticason.
English: Metabolism as well as biliary excretion of parent drug contribute to the elimination of paritaprevir.
Danish: Metabolisering samt biliær udskillelse af moderstoffet bidrager til eliminationen af paritaprevir.
English: When taking Viekirax with dasabuvir, tell your doctor if you have the following symptoms as they may be a sign of worsening liver problems:
Danish: Når du tager Viekirax sammen med dasabuvir, skal du fortælle det til din læge, hvis du får følgende symptomer, da de kan være tegn på forværrede leverproblemer.
English: It is very important that you also read the package leaflets for the other antiviral medicines that you take with Viekirax.
Danish: Det er meget vigtigt, at du også læser indlægssedlerne for de andre antivirale lægemidler, som du tager sammen med Viekirax.
English: Pharmacotherapeutic group: Antivirals for systemic use; direct-acting antivirals, ATC code: J05AP53
Danish: Farmakoterapeutisk klassifikation: Antivirale midler til systemisk brug; direkte virkende antivirale midler; ATC-kode: J05AP53
English: Some patients have reported feeling very tired when taking Viekirax with other medicines for their hepatitis C infection.
Danish: Nogle patienter har indberettet, at de følte sig meget trætte, når de tog Viekirax sammen med andre lægemidler mod hepatitis C-infektion.
English: No human data on the effect of Viekirax on fertility are available.
Danish: Der foreligger ingen humane data om Viekirax' indvirkning på fertiliteten.
English: • Swelling of the layers of skin which can affect any part of the body including the face, tongue or throat and may cause difficulty swallowing or breathing (angioedema)
Danish: • Hævelse i hudens lag, som kan påvirke alle dele af kroppen inklusive ansigtet, tungen eller halsen som kan give synke- eller vejrtrækningsbesvær (angioødem).
English: There was 1 relapse in the 12week arm and 1 on-treatment virologic failure in the 24-week arm.
Danish: Der var 1 tilbagefald i 12 ugers armen og 1 virologisk svigt under behandling i 24 ugers armen.
English: In vitro interaction data
Danish: Interaktionsdata in vitro
English: A decrease in alprazolam dose can be considered based on clinical response.
Danish: Nedsættelse af alprazolamdosen kan overvejes alt efter klinisk respons.
English: Trazodone should be used with caution and a lower dose of trazodone may be considered.
Danish: Trazodon bør anvendes med forsigtighed og reduktion af trazodon-dosis bør overvejes.
English: Ombitasvir and paritaprevir block two proteins essential for the virus to multiply.
Danish: Ombitasvir og paritaprevir blokerer to proteiner, der er afgørende for virussets formering.
English: Keep the medicine pack with you so that you can easily describe what you have taken.
Danish: Tag Viekirax-pakningen med, så du let kan beskrive, hvad du har taget.
English: Four subjects experienced a haemoglobin level < 8 g/dL.
Danish: Fire patienter oplevede et hæmoglobin-niveau < 8 g /dl.
English: In the genotype 1b replicon, the activity of ombitasvir was reduced by less than 10-fold by variants at amino acid positions 30 and 31.
Danish: I genotype 1b-replikonen blev aktiviteten af ombitasvir reduceret med mindre end 10 gange af varianter ved aminosyrepositionerne 30 og 31.
English: Dihydroergot amine
Danish: Dihydroergot amin
English: The efficacy of Viekirax has not been established in patients with HCV genotypes 2, 3, 5 and 6; therefore Viekirax should not be used to treat patients infected with these genotypes.
Danish: Virkningen af Viekirax er ikke klarlagt hos patienter med HCV-genotype 2, 3, 5 og 6; Viekirax må derfor ikke anvendes til behandling af patienter med disse genotyper.
English: Viekirax has no or negligible influence on the ability to drive and use machines.
Danish: Viekirax påvirker ikke eller kun i ubetydelig grad evnen til at føre motorkøretøj og betjene maskiner.
English: Malformations at low incidence were observed mainly in the eyes (microphthalmia) and teeth (absent incisors).
Danish: Der sås lav incidens af misdannelser, primært af øjne (mikroftalmi) og tænder (fravær af fortænder).
English: Examples are provided below.
Danish: Se eksemplerne nedenfor.
English: A total of 129 subjects were treated, 84 with GT1a, 41 with GT1b, 1 with GT1 other, 3 with GT4 infection.
Danish: I alt blev 129 forsøgspersoner behandlet, 84 med GT1a, 41 med GT1b, 1 med anden GT1, 3 med GT4infektion.
English: At least 5 minor metabolites of paritaprevir have been identified in circulation that accounted for approximately 10% of plasma radioactivity.
Danish: Mindst 5 mindre metabolitter af paritaprevir blev identificeret i kredsløbet, og de stod for ca. 10 % af radioaktiviteten i plasma.
English: The increase in exposure was similar regardless of meal type (e.g., high-fat versus moderate-fat) or calorie content (approximately 600 Kcal versus approximately 1000 Kcal).
Danish: Den øgede eksponering var den samme uanset madtype (f.eks. højt fedtindhold versus moderat fedtindhold) og kalorieindhold (ca. 600 kcal versus ca. 1.000 kcal).
English: Unchanged parent drug accounted for 88% of total radioactivity recovered in faeces, indicating that biliary excretion is a major elimination pathway for ombitasvir.
Danish: Uomdannet moderstof udgjorde 88 % af den samlede radioaktivitet, der blev genfundet i fæces, hvilket tyder på, at biliær udskillelse er en stor eliminationsvej for ombitasvir.
English: Examples of contraindicated strong or moderate enzyme inducers are provided below.
Danish: Eksempler på kontraindicerede stærke eller moderate enzym-inducere er angivet nedenfor.
English: These metabolites are not expected to have antiviral activity or off-target pharmacologic activity.
Danish: Disse metabolitter forventes ikke at have antiviral aktivitet eller farmakologisk off-target-aktivitet.
English: Treatment with Viekirax should be initiated and monitored by a physician experienced in the management of chronic hepatitis C.
Danish: Behandling med Viekirax skal påbegyndes og overvåges af en læge med erfaring i behandling af kronisk hepatitis C.
English: Buprenorphine / naloxone
Danish: Buprenorphin /naloxon
English: Decrease digoxin dose by 30-50%.
Danish: Reducér digoxin med 3050 %.
English: This regimen can be used in the absence of extensive PI resistance (i.e. lack of darunavir associated RAMs), see also section
Danish: Dette regime kan anvendes, hvis der ikke er udtalt PIresistens (dvs. hvis der ikke er nogen darunavirrelaterede RAM'er); se også pkt.
English: 10 kg change in body weight from 76 kg (median weight in the Phase 3 studies) would results in <10% change in ombitasvir exposures, and no change in paritaprevir exposures.
Danish: En ændring på 10 kg i legemsvægt fra 76 kg (median vægt fase 3-studierne) vil medføre en ændring på < 10% i eksponeringen for ombitasvir, og ingen ændring i eksponeringen for paritaprevir.
English: Limited data in patients with endstage renal disease indicate no clinically significant changes in exposure also in this patient group.
Danish: Begrænset dokumentation hos patienter med nyresygdom i slutstadiet indikerer ikke væsentlige kliniske ændringer i eksponeringen hos denne patientgruppe.
English: Appropriate monitoring of serum digoxin levels is recommended.
Danish: Passende monitorering af serumdigoxin anbefales.
English: Ombitasvir is metabolised via amide hydrolysis followed by oxidative metabolism.
Danish: Ombitasvir metaboliseres via amidhydrolyse efterfulgt af oxidativ metabolisering.
English: There are some medicines you must not take with Viekirax see the previous table “Medicines you must not take with Viekirax”.
Danish: Der er visse lægemidler, som du ikke må tage sammen med Viekirax - se ovenfor i tabellen "Lægemidler, du ikke må tage sammen med Viekirax".
English: Some diabetic patients have experienced low sugar levels in the blood (hypoglycaemia) after starting treatment with medicines like Viekirax.
Danish: Nogle patienter med diabetes har oplevet lavt blodsukker (hypoglykæmi) efter påbegyndelse af behandling med lægemidler som Viekirax.
English: Following administration of Viekirax
Danish: Efter administration af Viekirax
English: The effects of Viekirax during pregnancy are not known.
Danish: Viekirax virkning under graviditet er ukendt.
English: Inhibition of these transporters is not expected to show clinically relevant increases in exposures of ombitasvir and dasabuvir.
Danish: Hæmning af disse transportere forventes ikke at medføre en klinisk relevant stigning i eksponeringen for ombitasvir og dasabuvir.
English: PEARL II, III, and IV TURQUOISE II (subjects with cirrhosis)
Danish: PEARL II, III og IV TURQUOISE II (forsøgspersoner med cirrose)
English: If an HIV protease inhibitor is added (atazanavir, darunavir), rilpivirine exposure may increase even further and is, therefore, not recommended.
Danish: Hvis en hiv-proteasehæmmer tilføjes (atazanavir, darunavir), kan rilpivirin-eksponeringen øges endnu mere; derfor anbefales dette ikke.
English: Dose normalised parameters reported for methadone, buprenorphine and naloxone.
Danish: Der er rapporteret om dosisnormaliserede parametre for metadon, buprenorphin og naloxon.
English: Ritonavir did not exhibit a direct antiviral effect on the replication of HCV subgenomic replicons, and the presence of ritonavir did not affect the in vitro antiviral activity of paritaprevir.
Danish: Ritonavir viste ingen direkte antiviral effekt på replikationen af HCV-subgenomiske replikoner, og tilstedeværelsen af ritonavir havde ingen indvirkning på paritaprevirs antivirale aktivitet in vitro.
English: Main characteristics are shown below.
Danish: De vigtigste karateristika er vist nedenfor.
English: • More than 12 hours until your next dose - take the missed dose with food as soon as possible.
Danish: • over 12 timer til din næste dosis, så skal du hurtigst muligt tage den manglende dosis sammen med noget mad
English: SVR12 % (n/N) Outcome for subjects without SVR12
Danish: SVR12 % (n/N) Resultater for patienter uden SVR12
English: In order to evaluate the recurrence of hepatocellular carcinoma associated withViekirax, the MAH shall conduct and submit the results of a prospective safety study using data deriving from a cohort of a well-defined group of patients, based on an agreed protocol.
Danish: For at vurdere recidiv af hepatocellulært karcinom associeret med Viekirax skal indehaveren af markedsføringstilladelsen udføre og indsende resultaterne fra et prospektivt sikkerhedsstudie baseret på en vedtagen protokol med brug af data fra en kohorte af en veldefineret gruppe patienter.
English: The use of Viekirax in children and adolescents has not yet been studied.
Danish: Anvendelsen af Viekirax hos børn og unge er endnu ikke undersøgt.
English: The absolute bioavailability of ombitasvir and paritaprevir was approximately 50% when administered with food as Viekirax.
Danish: Ombitasvirs og paritaprevirs absolutte biotilgængelighed var ca. 50 %, når stofferne blev administreret som Viekirax med mad.
English: These medicines can affect the way Viekirax works and Viekirax can affect the way these other medicines work.
Danish: De kan påvirke den måde, Viekirax virker på, ligesom Viekirax kan påvirke den måde, de andre lægemidler virker på.
English: Overall, 72 of 79 treatment-naive subjects (45 of 52 GT1a and 27 of 27 GT1b) and 40 of 45 treatment-experienced subjects (21 of 26 GT1a and 19 of 19 GT1b) achieved SVR12 after 12 weeks of treatment.
Danish: I alt opnåede 72 ud af 79 behandlingsnaive forsøgspersoner (45 ud af 52 GT1a og 27 ud af 27 GT1b) og 40 ud af 45 behandlingserfarne forsøgspersoner (21 ud af 26 GT1a og 19 ud af 19 GT1b) SVR12 efter 12 ugers behandling.
English: • cisapride
Danish: • cisaprid
English: The proportion of subjects who permanently discontinued treatment due to adverse reactions was 0.2% (5/2,044) and 4.8% (99/2,044) of subjects had ribavirin dose reductions due to adverse reactions.
Danish: Andelen af forsøgspersoner, der stoppede behandlingen permanent på grund af bivirkninger, var 0,2 % (5/2.044) og 4,8 % (99/2.044) af forsøgspersonerne fik nedsat ribavirin-dosis på grund af bivirkninger.
English: 16 Weeks
Danish: 16 uger
English: 8 weeks may be considered in previously untreated genotype 1binfected patients with minimal to moderate fibrosis** (see section 5.1, GARNET study)
Danish: 8 uger kan overvejes hos tidligere ubehandlede genotype 1b-patienter med minimal til moderat fibrose** (se pkt.
English: Skin and subcutaneous tissue disorders Very common
Danish: Hud og subkutane væv Meget almindelig
English: Ritonavir is an in vitro inhibitor of OCT1, but the clinical relevance is unknown.
Danish: Ritonavir er en hæmmer af OCT1 in vitro, men den kliniske relevans er ikke kendt.
English: Treatment duration was 12 weeks for treatment naïve subjects, 12-24 weeks for treatment experienced subjects and 24 weeks for subjects with cirrhosis.
Danish: Behandlingsvarigheden var 12 uger for behandlingsnaive forsøgspersoner, 12-24 uger for behandlingserfarne forsøgspersoner og 24 uger for forsøgspersoner med cirrose.
English: All 3 (100%) subjects with GT4 infection who were post liver transplant achieved SVR12.
Danish: Alle 3 (100%) forsøgspersoner med GT4-infektion, som var levertransplanterede, opnåede SVR12.
English: • lurasidone
Danish: • lurasidon
English: See also Table 2 for specific advice on raltegravir and buprenorphine, which have been evaluated in drug interaction studies.
Danish: I tabel 2 er der specifikke anbefalinger for raltegravir og buprenorphin, som er undersøgt i lægemiddelinteraktionsstudier.
English: If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking Viekirax.
Danish: Hvis noget af ovenstående gælder for dig (eller du er i tvivl), skal du tale med lægen eller apotekspersonalet, før du tager Viekirax.
English: Total bilirubin >3-10 × ULN (grade 3) >10 × ULN (grade 4) *ULN: Upper limit of normal according to testing laboratory.
Danish: Total bilirubin > 3-10 × ULN (grad 3) > 10 × ULN (grad 4) *ULN: Øvre normalgrænse (Upper Limit of Normal) for laboratorieværdierne.
English: If ribavirin is co-administered with Viekirax, the contraindications regarding use of ribavirin during pregnancy apply (see also the Summary of Product Characteristics of ribavirin).
Danish: Hvis ribavirin administreres samtidig med Viekirax, gælder kontraindikationerne for brug af ribavirin under graviditet (se også produktresuméet for ribavirin).
English: Psychiatric disorders Very common
Danish: Psykiske forstyrrelser Meget almindelig
English: Ombitasvir Ombitasvir is an inhibitor of HCV NS5A which is essential for viral replication.
Danish: Ombitasvir Ombitasvir er en hæmmer af HCV-NS5A, der er afgørende for den virale replikation.
English: GASTROINTESTINAL PRODUCTS (PROPULSIVE) Cisapride
Danish: GASTROINTESTINALE MIDLER (MOTILITET) Cisaprid
English: Ritonavir acts as a ‘booster' to prolong the action of paritaprevir in the body.
Danish: Ritonavir fungerer som en 'booster', der forlænger paritaprevirs virkning i kroppen.
English: Changes for ombitasvir, paritaprevir and dasabuvir the same as shown for paracetamol above
Danish: Ændringer for ombitasvir, paritaprevir og dasabuvir er de samme, som for paracetamol vist ovenfor
English: Age, median (range) years Male gender, n (%) Prior HCV Treatment: naïve, n (%) Peg-IFN + RBV, n (%) Baseline albumin, median g/L < 35, n (%)
Danish: Alder, median (interval) år Mænd, køn, n (%) Tidligere HCV-behandling: naïve, n (%) Peg-IFN + RBV, n (%) Baseline albumin, median g/l < 35, n (%)
English: Such medicinal products include some statins (see Table 2), fexofenadine, repaglinide and angiotensin II receptor antagonists (e.g., valsartan).
Danish: Det gælder bl.a. visse statiner (se tabel 2), fexofenadin, repaglinid og angiotensin II-receptor-antagonister (f.eks. valsartan).
English: Body weight is not a significant predictor of ritonavir exposures.
Danish: Legemsvægt er ikke en signifikant indikator for ritonavir-eksponering.
English: • sildenafil (when used for the treatment of pulmonary arterial hypertension)
Danish: • sildenafil (ved behandling af pulmonal arteriel hypertension)
English: Medicines you must not take with Viekirax Medicine or active substance
Danish: Lægemidler, du ikke må tage sammen med Viekirax Lægemiddel eller aktivt stof
English: HCV genotype (GT)
Danish: HCVgenotype (GT)
English: Rilpivirine should be used cautiously, in the setting of repeated ECG monitoring.
Danish: Rilpivirin skal anvendes med forsigtighed og under løbende EKG monitorering.
English: Resistance-associated variants at amino acid positions R155 and D168 in NS3 were rarely observed (less than 1%) at baseline.
Danish: Resistensrelaterede varianter ved aminosyrepositionerne R155 og D168 i NS3 sås sjældent (under 1 %) ved baseline.
English: All treatment-emergent variants in NS5A remained detectable at post-treatment Week 48.
Danish: Alle behandlingsrelaterede varianter i NS5A var stadig detekterbare 48 uger efter behandlingen.
English: Adverse events of anaemia were not seen in the 18 GT1b-infected subjects who did not receive ribavirin.
Danish: Anæmi-bivirkninger sås ikke hos de 18 GT1b-inficerede patienter, som ikke fik ribavirin.
English: The direction of the arrow indicates the direction of the change in exposures (Cmax, and AUC) in paritaprevir, ombitasvir, dasabuvir and the co-administered medicinal product (↑ = increase (more than 20%), ↓ = decrease (of more than 20%), ↔ = no change or change less than 20%).
Danish: Pilens retning angiver ændringen i eksponering (Cmax og AUC) for paritaprevir, ombitasvir, dasabuvir og det samtidigt administrerede lægemiddel (↑= stigning på over 20 %, ↓ = fald på over 20 %, ↔ = ingen ændring eller ændring på under 20 %).
English: It is not known whether paritaprevir /ritonavir or ombitasvir and their metabolites are excreted in human breast milk.
Danish: Det er ukendt, om paritaprevir/ritonavir og ombitasvir og deres metabolitter udskilles i human mælk.
English: When starting coadministration with Viekirax, give one fifth of the total daily dose of ciclosporin once daily with Viekirax.
Danish: Ved administration samtidig med Viekirax skal man i starten administrere en femtedel af den samlede daglige dosis ciclosporin én gang dagligt sammen med Viekirax.
English: • Monitoring should be performed for clinical signs and symptoms of hepatic decompensation (such as ascites, hepatic encephalopathy, variceal haemorrhage).
Danish: Overvågning skal udføres for kliniske tegn og symptomer på dekompenseret leversygdom (såsom ascites, hepatisk encefalopati og varice-blødning).
English: These medicinal products may show clinically relevant increases in exposures of paritaprevir (e.g., ritonavir with atazanavir, erythromycin, diltiazem or verapamil).
Danish: Disse lægemidler kan give klinisk relevante stigninger i eksponeringen for paritaprevir (f.eks. ritonavir sammen med atazanavir, erythromycin, diltiazem eller verapamil).
English: Transient increases in indirect bilirubin were observed at the highest doses of paritaprevir/ritonavir.
Danish: Forbigående stigninger i ikke-konjugeret bilirubin sås ved de højeste doser af paritaprevir/ritonavir.
English: If you forget to take Viekirax
Danish: Hvis du har glemt at tage Viekirax
English: Rilpivirine was also administered in the evening with food and at night 4 hours after dinner with Viekirax + dasabuvir in other two arms in the study.
Danish: Rilpivirin blev også administreret om aftenen med et måltid og om natten 4 timer efter aftensmaden sammen med Viekirax med dasabuvir i to andre grupper i studiet.
English: Efavirenz/ emtricitabine/ tenofovir disoproxil fumarate mg once daily
Danish: Efavirenz/emtricitabin/tenofovirdisoproxilfumarat mg én gang dagligt
English: ALT elevations were typically asymptomatic, generally occurred during the first 4 weeks of treatment (mean time 20 days, range 8-57 days) and most resolved with ongoing therapy.
Danish: ALAT-forhøjelserne var typisk asymptomatiske, forekom generelt i løbet af de første 4 uger af behandlingen (middelvarighed 20 dage, interval 8-57 dage) og forsvandt for de flestes vedkommende ved fortsat behandling.
English: Cases of hepatitis B virus (HBV) reactivation, some of them fatal, have been reported during or after treatment with direct-acting antiviral medicinal products.
Danish: Der er rapporteret om tilfælde af reaktivering af hepatitis B-virus (HBV), herunder dødelige tilfælde, under eller efter behandling med direkte virkende antivirale lægemidler.
English: Overall, 107 of 113 subjects without cirrhosis and 147 of 155 subjects with cirrhosis achieved SVR12 after 12-24 weeks of treatment.
Danish: 107 ud af de 113 forsøgspersoner uden cirrose og 147 ud af de 155 forsøgspersoner med cirrose opnåede SVR12 efter 12-24 ugers behandling.
English: Coadministration of Viekirax with other antivirals has not been studied and, therefore, cannot be recommended.
Danish: Samtidig administration af Viekirax og andre antivirale midler er ikke undersøgt og anbefales derfor ikke.
English: Viekirax should be used in combination with other medicinal products for the treatment of HCV (see Table 1).
Danish: Viekirax skal anvendes i kombination med andre lægemidler til behandling af HCV (se tabel 1).
English: AFP* < 20 ng/mL, platelets ≥ 90 x 109/L, AND albumin ≥ 35 g/L prior to treatment
Danish: AFP* < 20 ng/ml, trombocyttal ≥ 90 x 109/l og albumin ≥ 35 g/l før behandling
English: Viekirax may increase the plasma exposure to medicinal products that are sensitive for changed intestinal P-gp activity (such as dabigatran etexilate).
Danish: Viekirax kan øge plasmaeksponeringen for lægemidler, der er følsomme over for ændret P-gp-aktivitet i tarmen (f.eks. dabigatranetexilat).
English: ANTIDEPRESSANTS Escitalopram
Danish: ANTIDEPRESSIVA Escitalopram
English: ↔ dasabuvir sirolimus is used together with Viekirax + dasabuvir, administer sirolimus 0.2 mg twice a week (every 3 or 4 days on the same two days each week).
Danish: 4.4) Hvis sirolimus anvendes sammen med Viekirax + dasabuvir, administreres sirolimus 0,2 mg to gange om ugen (hver 3. eller 4. dag på de samme to dage hver uge).
English: However, no dose-adjustment based on gender is warranted.
Danish: Dosisjustering på grund af køn forventes dog ikke at være nødvendig.
English: Ombitasvir, paritaprevir and ritonavir were absorbed after oral administration with mean Tmax of approximately 4 to 5 hours.
Danish: Ombitasvir, paritaprevir og ritonavir blev absorberet efter oral administration med en gennemsnitlig Tmax på ca. 4-5 timer.
English: Sustained virologic response (SVR) was the primary endpoint to determine the HCV cure rate in the Phase 3 studies and was defined as unquantifiable or undetectable HCV RNA 12 weeks after the end of treatment (SVR12).
Danish: Vedvarende virologisk respons (sustained virologic respons (SVR)) var det primære endepunkt til bestemmelse af helbredelsesraten for HCV i fase 3-studier og blev defineret som ikke-kvantificerbar eller ikke-påviselig HCV-rna 12 uger efter behandlingsafslutning (SVR12).
English: • itraconazole, ketoconazole, posaconazole, voriconazole
Danish: • itraconazol, ketoconazol, posaconazol, voriconazol
English: Ritonavir is not active against HCV. Ritonavir is a CYP3A inhibitor that increases the systemic exposure of the CYP3A substrate paritaprevir.
Danish: Ritonavir virker ikke mod HCV. Ritonavir er en CYP3A-hæmmer, der øger den systemiske eksponering for CYP3A-substratet paritaprevir.
English: ANTI-DIURETIC HORMONE Conivaptan
Danish: ANTIDIURETISK HORMON Conivaptan