FrancophonIA/ELRC3.0 huggingface dataset:
English: Serious skin rash, including Stevens-Johnson syndrome, has been reported in patients taking REYATAZ.
Slovenian: Pri bolnikih, ki so se zdravili z zdravilom REYATAZ, so poročali o pojavu resnega kožnega izpuščaja, vključno s Stevens-Johnsonovim sindromom.
English: Haemophiliac patients: There have been reports of increased bleeding, including spontaneous skin haematomas and haemarthroses, in type A and B haemophiliac patients treated with protease inhibitors.
Slovenian: Bolniki s hemofilijo: Pri bolnikih s hemofilijo A ali B, ki so dobivali zaviralce proteaz, so poročali o pogostejših krvavitvah, vključno s spontanimi kožnimi hematomi in hemartrozami.
English: HORMONAL CONTRACEPTIVES Ethinyloestradiol 25 μg + norgestimate (atazanavir 300 mg once daily with ritonavir 100 mg once daily)
Slovenian: HORMONSKI KONTRACEPTIVI Etinilestradiol 25 μg + norgestimat (atazanavir 300 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan)
English: Concomitant use of St. John's wort with REYATAZ/ritonavir may be expected to result in significant reduction in plasma levels of atazanavir.
Slovenian: Pri sočasni uporabi šentjanževke in zdravila REYATAZ/ritonavirja lahko pričakujemo pomembno zmanjšanje plazemskih vrednosti atazanavirja.
English: AI424-451 (PRINCE II): In paediatric patients from 3 months to less than 11 years of age In these studies, 155 patients (59 antiretroviral-naive and 96 antiretroviral-experienced) received once daily REYATAZ oral powder and ritonavir, in combination with two NRTIs.
Slovenian: V teh študijah je 155 bolnikov (59 bolnikov se predhodno še ni zdravilo s protiretrovirusnimi zdravili, 96 bolnikov pa se je predhodno že zdravilo s protiretrovirusnimi zdravili) prejemalo zdravilo REYATAZ v obliki peroralnega praška enkrat na dan in ritonavir v kombinaciji z dvema NRTI-jema.
English: Concomitant use of salmeterol and REYATAZ may result in increased cardiovascular adverse events associated with salmeterol.
Slovenian: Pri sočasni uporabi salmeterola in zdravila REYATAZ se lahko poveča pojavnost kardiovaskularnih neželenih učinkov salmeterola.
English: Six of 20 (30%) women on REYATAZ/ritonavir 300/100 mg and 13 of 21 (62%) women on REYATAZ/ritonavir 400/100 mg experienced grades 3 to 4 hyperbilirubinaemia.
Slovenian: Pri šestih od 20 bolnic (30%), ki so prejemale zdravilo REYATAZ/ritonavir v odmerku 300/100 mg, in 13 od 21 bolnic (62%), ki so prejemale zdravilo REYATAZ/ritonavir v odmerku 400/100 mg, so poročali o pojavu hiperbilirubinemije stopnje 3 do 4.
English: Bepridil
Slovenian: OPIOIDI
English: triazolam and oral (taken by mouth) midazolam (used to help you sleep and/or to relieve anxiety) simvastatin and lovastatin (used to lower blood cholesterol).
Slovenian: pripravki, ki vsebujejo šentjanževko (Hypericum perforatum, zdravilo rastlinskega izvora), triazolam in peroralne oblike (ki se jih jemlje skozi usta) midazolama (uporabljamo jih kot pomoč pri težavah s spanjem in/ali za ublažitev tesnobe), simvastatin in lovastatin (uporabljamo ju za zniževanje holesterola v krvi).
English: Stop taking REYATAZ and talk to your doctor immediately if you develop a severe rash or a rash with flu-like illness symptoms, blisters, fever, mouth sores, muscle or joint pain, swelling in the face, inflammation of the eye which causes redness (conjunctivitis), painful, warm, or red lumps (nodules).
Slovenian: Če opazite hud izpuščaj ali izpuščaj, ki ga spremljajo simptomi, podobni gripi, mehurji, zvišana telesna temperatura, razjede v ustih, bolečina v mišicah ali sklepih, otekanje obraza, vnetje oči s posledično rdečino oči (konjunktivitis), boleči, topli ali rdeči vozliči (noduli), zdravilo REYATAZ takoj prenehajte jemati in se nemudoma posvetujte z zdravnikom.
English: A change in dose may occur when switching between oral powder and capsules.
Slovenian: Pri zamenjavi med peroralnim praškom in kapsulami se bo odmerek morda spremenil.
English: The co-administration of REYATAZ/ ritonavir with abacavir is not expected to significantly alter the exposure of abacavir.
Slovenian: Pri sočasni uporabi zdravila REYATAZ/ritonavirja z abakavirjem pomembnejših sprememb v izpostavljenosti abakavirju ni pričakovati.
English: Atazanavir (am): 1 hr after omeprazole Atazanavir AUC ↓30% (↓43% ↓14%) * Atazanavir Cmax ↓31% (↓42% ↓17%) * Atazanavir Cmin ↓31% (↓46% ↓12%) *
Slovenian: Atazanavir (dopoldan): 1 uro po omeprazolu Atazanavir AUC ↓30% (↓43% ↓14%) * Atazanavir Cmax ↓31% (↓42% ↓17%) * Atazanavir Cmin ↓31% (↓46% ↓12%) *
English: REYATAZ 150 mg hard capsules
Slovenian: REYATAZ 150 mg trde kapsule
English: 300 mg (6 sachetsb)
Slovenian: 300 mg (6 vrečicb)
English: Ethinyloestradiol AUC ↓19% (↓25% Ethinyloestradiol Cmax ↓16% (↓26% Ethinyloestradiol Cmin ↓37% (↓45%
Slovenian: Etinilestradiol AUC ↓19% (↓25% ↓13%) Etinilestradiol Cmax ↓16% (↓26% ↓5%) Etinilestradiol Cmin ↓37% (↓45% ↓29%)
English: In HIV-infected patients with atazanavir/ritonavir at the recommended dose 300/100 mg once daily
Slovenian: Pri z virusom HIV okuženih bolnikih, ki so se zdravili z atazanavirjem/ritonavirjem v priporočenem odmerku 300/100 mg enkrat na dan
English: Ethinyloestradiol AUC ↑48% (↑31% Ethinyloestradiol Cmax ↑15% (↓1% Ethinyloestradiol Cmin ↑91% (↑57%
Slovenian: Etinilestradiol AUC ↑48% (↑31% ↑68%) Etinilestradiol Cmax ↑15% (↓1% ↑32%) Etinilestradiol Cmin ↑91% (↑57% ↑133%)
English: Due to carbamazepine inducing effect, a reduction in REYATAZ exposure cannot be ruled out.
Slovenian: Zaradi inducirajočega učinka karbamazepina zmanjšanja izpostavljenosti zdravilu REYATAZ ne moremo izključiti.
English: Buprenorphine, once daily, stable maintenance dose (atazanavir 300 mg once daily with ritonavir 100 mg once daily)
Slovenian: Buprenorfin enkrat na dan, stabilni vzdrževalni odmerek (atazanavir 300 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan)
English: Norgestimate AUC ↑85% (↑67% Norgestimate Cmax ↑68% (↑51% Norgestimate Cmin ↑102% (↑77%
Slovenian: Norgestimat AUC ↑85% (↑67% ↑105%) Norgestimat Cmax ↑68% (↑51% ↑88%) Norgestimat Cmin ↑102% (↑77% ↑131%)
English: The child is to drink the mixture.
Slovenian: Otrok naj pripravljeno mešanico izpije.
English: Voriconazole AUC ↓33% (↓42% Voriconazole Cmax ↓10% (↓22% ↓4%) Voriconazole Cmin ↓39% (↓49% ↓28%)
Slovenian: Vorikonazol AUC ↓33% (↓42% ↓22%) Vorikonazol Cmax ↓10% (↓22% ↓4%) Vorikonazol Cmin ↓39% (↓49% ↓28%)
English: Due to carbamazepine inducing effect, a reduction in REYATAZ/ritonavir exposure cannot be ruled out.
Slovenian: Zaradi inducirajočega učinka karbamazepina zmanjšanja izpostavljenosti zdravilu REYATAZ/ritonavir ne moremo izključiti.
English: De novo substitutions in treatment experienced patients failing therapy with atazanavir + ritonavir (Study 045, 48 weeks) Frequency de novo PI substitution (n=35)a,b M36, M46, I54, A71, V82 L10, I15, K20, V32, E35, S37, F53, I62, G73, I84, L90
Slovenian: Nova substitucija zaviralca proteaz (n=35)a,b M36, M46, I54, A71, V82 L10, I15, K20, V32, E35, S37, F53, I62, G73, I84, L90
English: The pharmacokinetic data from HIV-infected pregnant women receiving REYATAZ capsules with ritonavir are presented in Table 9.
Slovenian: V preglednici 9 so predstavljeni farmakokinetični podatki, pridobljeni pri z virusom HIV okuženih nosečnicah, ki so prejemale zdravilo REYATAZ v obliki kapsul skupaj z ritonavirjem.
English: Cmax ng/mL
Slovenian: Cmax ng/ml geometrična sredina (KV%)
English: Co-administration of REYATAZ with ritonavir and medicinal products that induce CYP3A4 is not recommended (see sections 4.3 and 4.5).
Slovenian: Zdravila REYATAZ z ritonavirjem ni priporočljivo uporabljati skupaj z zdravili, ki inducirajo CYP3A4 (glejte poglavji 4.3 in 4.5).
English: If you get any side effects talk to your doctor, or pharmacist.
Slovenian: Če opazite kateri koli neželeni učinek, se posvetujte z zdravnikom ali farmacevtom.
English: Ritonavir Dose once daily (mg)
Slovenian: Odmerek ritonavirja enkrat na dan (mg)
English: HIV RNA <400 copies/ml, % a All patients
Slovenian: HIV RNA <400 kopij/ml, % a Vsi bolniki
English: A safe and effective dose in combination with REYATAZ has not been established for sildenafil when used to treat pulmonary arterial hypertension.
Slovenian: Varnega in učinkovitega odmerka sildenafila za zdravljenje pljučne arterijske hipertenzije, ki bi ga lahko uporabljali skupaj z zdravilom REYATAZ, niso ugotovili.
English: No dose adjustment is needed for REYATAZ.
Slovenian: Odmerka zdravila REYATAZ ni treba prilagajati.
English: 200 mg (4 sachetsa)
Slovenian: 200 mg (4 vrečicea)
English: Co-administration of voriconazole and REYATAZ/ritonavir is not recommended unless an assessment of the benefit/risk to the patient justifies the use of voriconazole (see section 4.4).
Slovenian: Sočasna uporaba vorikonazola in zdravila REYATAZ/ritonavirja ni priporočljiva, razen če ocena koristi/tveganj pri bolniku upraviči uporabo vorikonazola (glejte poglavje 4.4).
English: Another 10 ml of formula is poured into the medicine cup or small container to rinse off remaining REYATAZ oral powder in the cup or container.
Slovenian: V merico za odmerjanje zdravila ali manjšo posodico nalijte dodatnih 10 ml začetne formule za dojenčke in izplaknite preostali REYATAZ peroralni prašek v merici ali posodici.
English: Carton Bottle pack (1 bottle): 60 hard capsules Carton Bottle pack: (3 bottles): 3 x 60 hard capsules (3 bottles of 60 hard capsules) Label Bottle pack: 60 hard capsules
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Škatla, pakiranje v plastenki (1 plastenka): 60 trdih kapsul Škatla, pakiranje v plastenki (3 plastenke): 3 x 60 trdih kapsul (3 plastenke po 60 trdih kapsul) Nalepka, pakiranje v plastenki: 60 trdih kapsul
English: The capsule shell and printing ink contain gelatine, shellac, ammonium hydroxide, simethicone, red iron oxide, black iron oxide, yellow iron oxide, propylene glycol, indigocarmin (E132) and titanium dioxide (E171).
Slovenian: Ovojnica kapsule in tiskarsko črnilo vsebujeta želatino, šelak, amonijev hidroksid, simetikon, rdeči železov oksid, črni železov oksid, rumeni železov oksid, propilenglikol, indigotin (E132) in titanov dioksid (E171).
English: Study 138 is an international randomised, open-label, multicenter, prospective trial of 883 antiretroviral treatment naive patients comparing REYATAZ/ritonavir (300 mg/100 mg once daily) to lopinavir/ritonavir (400 mg/100 mg twice daily), each in combination with fixed dose tenofovir disoproxil fumarate/emtricitabine (300 mg/200 mg tablets once daily).
Slovenian: Pri odraslih bolnikih, ki se predhodno še niso zdravili s protiretrovirusnimi zdravili Študija 138 je mednarodno, randomizirano, odprto, multicentrično, prospektivno preskušanje, ki je pri 883 bolnikih, ki se predhodno še niso zdravili s protiretrovirusnimi zdravili, primerjalo uporabo zdravila REYATAZ/ritonavirja (300 mg/100 mg enkrat na dan) z uporabo lopinavirja/ritonavirja (400 mg/100 mg dvakrat na dan), oboje v kombinaciji s fiksnimi odmerki dizoproksiltenofovirijevega fumarata/emtricitabina (300 mg/200 mg tablete enkrat na dan).
English: Didanosine (enteric coated capsules) 400 mg single dose (atazanavir 300 mg once daily with ritonavir 100 mg once daily)
Slovenian: Didanozin (gastrorezistentne kapsule) 400 mg enkratni odmerek (atazanavir 300 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan)
English: Glecaprevir 300 mg / pibrentasvir 120 mg once daily (atazanavir 300 mg / ritonavir 100 mg once daily*)
Slovenian: Glecaprevir 300 mg / pibrentasvir 120 mg enkrat na dan (atazanavir 300 mg / ritonavir 100 mg enkrat na dan*)
English: REYATAZ/ritonavir may result in increased concentrations of the PDE5 inhibitor and an increase in PDE5associated adverse events, including hypotension, visual changes, and priapism.
Slovenian: Pri sočasni uporabi z zdravilom REYATAZ/ritonavirjem se lahko koncentracije zaviralca PDE5 povečajo in pojavijo njegovi neželeni učinki, kot so hipotenzija, spremembe vida in priapizem.
English: REYATAZ (without ritonavir) has been studied in adult patients with severe renal impairment (n=20), including those on haemodialysis, at multiple doses of 400 mg once daily.
Slovenian: Uporabo zdravila REYATAZ (brez ritonavirja) so raziskovali pri odraslih bolnikih s hudo okvaro ledvic (n=20), vključno z bolniki, ki so se zdravili s hemodializo.
English: REYATAZ Dose once daily (mg)
Slovenian: Odmerek zdravila REYATAZ enkrat na dan (mg)
English: Concomitant use of St. John's wort with REYATAZ may be expected to result in significant reduction in plasma levels of atazanavir.
Slovenian: Pri sočasni uporabi šentjanževke in zdravila REYATAZ lahko pričakujemo pomembno zmanjšanje plazemskih vrednosti atazanavirja.
English: 250 mg (5 sachetsb)
Slovenian: 250 mg (5 vrečic b)
English: Ritonavir 100 mg once daily (atazanavir 300 mg once daily)
Slovenian: Ritonavir 100 mg enkrat na dan (atazanavir 300 mg enkrat na dan)
English: 300 mg (6 sachetsa)
Slovenian: 300 mg (6 vrečica)
English: For treatment experienced paediatric patients, the mean baseline CD4 cell count was 522 cells/mm3 (range: 100 to 1157 cells/ mm3) and mean baseline plasma HIV-1 RNA was 4.09 log10 copies/ml (range: 3.28 to 5.00 log10 copies/ml).
Slovenian: Pri bolnikih, ki so predhodno že prejemali tovrstno zdravljenje, je bilo povprečno število celic CD4 na začetku 522 celic/mm3 (območje: 100 do 1.157 celic/mm3) in povprečna začetna plazemska vrednost HIV-1 RNA 4,09 log10 kopij/ml (območje: 3,28 do 5,00 log10 kopij/ml).
English: ANTIMYCOBACTERIAL
Slovenian: KORTIKOSTEROIDI
English: Co-administration with REYATAZ/ritonavir may result in increased concentrations of the PDE5 inhibitor and an increase in PDE5inhibitor-associated adverse events.
Slovenian: Pri sočasni uporabi zdravila REYATAZ/ritonavirja se koncentracije zaviralca PDE5 lahko povečajo in s tem se poveča tudi pojavnost neželenih učinkov zaviralca PDE5.
English: REYATAZ/ritonavir may increase plasma levels of carbamazepine due to CYP3A4 inhibition.
Slovenian: Zdravilo REYATAZ/ritonavir lahko z zaviranjem CYP3A4 zviša vrednosti karbamazepina v plazmi.
English: Talk to your doctor immediately if you get dark (tea-colored) urine, itching, yellowing of your skin or the white part of your eyes, pain around the stomach, pale colored stools or nausea.
Slovenian: V primeru temnega urina (barva čaja), srbenja, rumenega obarvanja kože ali očesnih beločnic, bolečine v trebuhu, svetlega blata ali siljenja na bruhanje, se nemudoma posvetujte z zdravnikom.
English: Study 138 is an international randomised, open-label, multicenter, prospective trial of treatment naïve patients comparing REYATAZ/ritonavir (300 mg/100 mg once daily) to lopinavir/ritonavir (400 mg/100 mg twice daily), each in combination with fixed dose tenofovir disoproxil fumarate/emtricitabine (300 mg/200 mg tablets once daily).
Slovenian: Pri odraslih bolnikih, ki se predhodno še niso zdravili s protiretrovirusnimi zdravili Študija 138 je mednarodno, randomizirano, odprto, multicentrično, prospektivno preskušanje, ki je pri predhodno še nezdravljenih bolnikih primerjalo uporabo zdravila REYATAZ/ritonavirja (300 mg/100 mg enkrat na dan) z uporabo lopinavirja/ritonavirja (400 mg/100 mg dvakrat na dan), oboje v kombinaciji s fiksnimi odmerki dizoproksiltenofovirijevega fumarata/emtricitabina (300 mg/200 mg tablete enkrat na dan).
English: Sildenafil, tadalafil, vardenafil Sildenafil, tadalafil, and vardenafil are metabolised by CYP3A4.
Slovenian: Sildenafil, tadalafil, vardenafil
English: The combination of rifampicin and REYATAZ is contraindicated (see section 4.3).
Slovenian: Sočasna uporaba rifampicina in zdravila REYATAZ je kontraindicirana (glejte poglavje 4.3).
English: TreatmentExperienced REYATAZ Capsules/ritonavir (300 mg/100 mg once daily) n=25
Slovenian: Zdravljenje bolnikov, ki so že prejemali kapsule REYATAZ /ritonavir (300 mg/100 mg enkrat na dan) n=25
English: Norethindrone AUC ↑110% (↑68% Norethindrone Cmax ↑67% (↑42% Norethindrone Cmin ↑262% (↑157%
Slovenian: Noretindron AUC ↑110% (↑68% ↑162%) Noretindron Cmax ↑67% (↑42% ↑196%) Noretindron Cmin ↑262% (↑157% ↑409%)
English: Co-administration of voriconazole and REYATAZ with ritonavir is not recommended unless an assessment of the benefit/risk to the patient justifies the use of voriconazole (see section 4.4).
Slovenian: Sočasna uporaba vorikonazola in zdravila REYATAZ z ritonavirjem ni priporočljiva, razen če ocena koristi/tveganj pri bolniku upraviči uporabo vorikonazola (glejte poglavje 4.4).
English: Due to phenitoine/phenobarbital inducing effect, a reduction in REYATAZ/ritonavir exposure cannot be ruled out
Slovenian: Zaradi inducirajočega učinka fenitoina/fenobarbitala zmanjšanja izpostavljenosti zdravilu REYATAZ/ritonavir ne moremo izključiti.
English: If the combination of REYATAZ with a proton pump inhibitor is judged unavoidable, close clinical monitoring is recommended in combination with an increase in the dose of REYATAZ to 400 mg with 100 mg of ritonavir; doses of proton pump inhibitors comparable to omeprazole 20 mg should not be exceeded.
Slovenian: Če je uporaba zdravila REYATAZ/ritonavirja z zaviralcem protonske črpalke nujna, je potreben skrben klinični nadzor, odmerek zdravila REYATAZ pa je treba povečati na 400 mg in ga uporabljati skupaj z ritonavirjem v odmerku 100 mg. Odmerkov zaviralcev protonske črpalke, ki so primerljivi z 20 mg omeprazola, se ne sme preseči.
English: Co-administration with glecaprevir/pibrentasvir fixed dose combination (see section 4.5).
Slovenian: Sočasna uporaba s fiksno kombinacijo glecaprevir/pibrentasvir (glejte poglavje 4.5).
English: If a higher dose of an H2-receptor antagonist is required (e.g., famotidine 40 mg twice daily or equivalent) an increase of the REYATAZ/ritonavir dose from 300/100 mg to 400/100 mg can be considered.
Slovenian: Če je potreben večji odmerek antagonista histaminskih receptorjev H2 (npr. famotidin 40 mg dvakrat na dan ali ekvivalenten odmerek), je treba razmisliti o povečanju odmerka zdravila
English: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Efavirenz 600 mg once daily (atazanavir 400 mg once daily with ritonavir 100 mg once daily)
Slovenian: Nenukleozidni zaviralci reverzne transkriptaze (NNRTI-ji) Efavirenz 600 mg enkrat na dan (atazanavir 400 mg enkrat na dan z ritonavirjem
English: Carbamazepine should be used with caution in combination with REYATAZ/ritonavir.
Slovenian: Karbamazepin je treba v kombinaciji z zdravilom REYATAZ/ritonavir uporabljati previdno.
English: Coadministration with REYATAZ may result in increased concentrations of the PDE5 inhibitor and an increase in PDE5-associated adverse events, including hypotension, visual changes, and priapism.
Slovenian: Pri sočasni uporabi z zdravilom REYATAZ se lahko koncentracije zaviralca PDE5 povečajo in pojavijo njegovi neželeni učinki, kot so hipotenzija, spremembe vida in priapizem.
English: Co-administration of REYATAZ/ritonavir with quetiapine is contraindicated as may increase quetiapine-related toxicity.
Slovenian: Sočasna uporaba zdravila REYATAZ/ritonavirja in kvetiapina je kontraindicirana, saj se lahko okrepijo toksični učinki kvetiapina.
English: REYATAZ capsules are available for paediatric patients at least 6 years of age who weigh at least 15 kg and who are able to swallow capsules (see Summary of Product Characteristics for REYATAZ
Slovenian: Za pediatrične bolnike, stare najmanj 6 let in s telesno maso najmanj 15 kg, ki lahko pogoltnejo kapsule, je zdravilo REYATAZ na voljo v obliki kapsul (glejte povzetek glavnih značilnosti zdravila REYATAZ kapsule).
English: Co-administration of REYATAZ with ritonavir and proton pump inhibitors is not recommended.
Slovenian: Sočasne uporabe zdravila REYATAZ z ritonavirjem in zaviralcev protonske črpalke ne priporočamo.
English: Race: a population pharmacokinetic analysis of samples from Phase II clinical trials indicated no effect of race on the pharmacokinetics of atazanavir.
Slovenian: Rasa: proučevanje populacijske farmakokinetike v študijah II.
English: Serum concentrations of verapamil may be increased by REYATAZ due to CYP3A4 inhibition.
Slovenian: Pri sočasni uporabi z zdravilom REYATAZ se lahko serumske koncentracije verapamila povečajo zaradi inhibicije CYP3A4.
English: The pharmacokinetic data from HIV-infected pregnant women receiving REYATAZ capsules with ritonavir are presented in Table 8.
Slovenian: V preglednici 8 so predstavljeni farmakokinetični podatki, pridobljeni pri z virusom HIV okuženih nosečnicah, ki so prejemale zdravilo REYATAZ v obliki kapsul skupaj z ritonavirjem.
English: Add an additional tablespoon in the container, mix and feed to your child again.
Slovenian: V posodico dodajte še eno jedilno žlico in premešajte, otrok pa naj zaužije tudi to mešanico.
English: Concentrations of these antiarrhythmics may be increased when co-administered with REYATAZ.
Slovenian: Pri sočasni uporabi z zdravilom REYATAZ se lahko koncentracije teh antiaritmikov povečajo.
English: HIV RNA <50 copies/ml, % a All patients
Slovenian: HIV RNA <50 kopij/ml, % a Vsi bolniki
English: REYATAZ with ritonavir must not be used in patients with moderate to severe hepatic impairment (see sections 4.3, 4.4 and 5.2).
Slovenian: REYATAZ se z ritonavirjem ne sme uporabljati pri bolnikih z zmerno do hudo okvaro jeter (glejte poglavja 4.3, 4.4 in 5.2).
English: Dose related asymptomatic prolongations in PR interval with REYATAZ have been observed in clinical studies.
Slovenian: Pri zdravljenju z zdravilom REYATAZ so v kliničnih študijah opazili od odmerka odvisno asimptomatsko podaljšanje intervala PR.
English: These are listed under Do not take REYATAZ, at the start of Section 2.
Slovenian: Zdravila REYATAZ ne smete jemati z nekaterimi drugimi zdravili, ki so navedena na začetku poglavja 2 pod Ne jemljite zdravila REYATAZ.
English: 3) and mean baseline plasma HIV-1 RNA was 4.09 log10 copies/ml (range: 3.28 to 5.00 log10 copies/ml).
Slovenian: 3), srednja vrednost plazemske HIV-1 RNA v izhodišču pa 4,67 log10 kopij/ml (razpon od 2,0 do 5,9 log10 kopij/ml).
English: Atazanavir AUC ↔0%(↓9% ↑10%)* Atazanavir Cmax ↑17%(↑8% ↑27%)* Atazanavir Cmin ↓42%(↓51% ↓31%)*
Slovenian: Atazanavir (popoldan): vse skupaj s hrano Atazanavir AUC ↔0%(↓9% ↑10%)* Atazanavir Cmax ↑17%(↑8% ↑27%)* Atazanavir Cmin ↓42%(↓51% ↓31%)*
English: REYATAZ 50 mg oral powder atazanavir
Slovenian: REYATAZ 50 mg peroralni prašek atazanavir
English: Store in the original package
Slovenian: Shranjujte v originalni ovojnini.
English: If the patient has developed SJS or DRESS associated with the use of REYATAZ, REYATAZ may not be restarted.
Slovenian: Če se pri bolniku zaradi zdravljenja z zdravilom REYATAZ pojavita Stevens-Johnsonov sindrom ali sindrom DRESS, zdravljenja z zdravilom REYATAZ morda ne boste smeli ponovno uvesti.
English: Co-administration of REYATAZ/ritonavir with alfuzosin is contraindicated (see section 4.3)
Slovenian: Sočasna uporaba zdravila REYATAZ/ritonavirja in alfuzosina je kontraindicirana (glejte poglavje 4.3).
English: INFORMATION IN BRAILLE Outer carton: REYATAZ 200 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Škatla: REYATAZ 200 mg
English: For patients who are taking tenofovir disoproxil fumarate, if REYATAZ/ritonavir with both tenofovir disoproxil fumarate and an H2-receptor antagonist are co-administered, a dose increase of REYATAZ to 400 mg with 100 mg of ritonavir is recommended.
Slovenian: Pri bolnikih, ki se zdravijo z dizoproksiltenofovirijevim fumaratom: če se sočasno uporablja zdravilo REYATAZ/ritonavir v kombinaciji z obema, dizoproksiltenofovirijevim fumaratom in antagonistom histaminskih receptorjev H2, je priporočljivo, da se odmerek zdravila REYATAZ poveča na 400 mg in uporablja skupaj z ritonavirjem v odmerku 100 mg. Odmerka, ki je primerljiv s 40 mg famotidina dvakrat na dan,
English: NAME OF THE MEDICINAL PRODUCT REYATAZ 50 mg oral powder atazanavir
Slovenian: IME ZDRAVILA REYATAZ 50 mg peroralni prašek atazanavir
English: Total rifabutin and 25-O-desacetyl-rifabutin AUC ↑119% (↑78% ↑169%).
Slovenian: 25-O-dezacetil-rifabutin AUC ↑990% (↑714%
English: H2-Receptor antagonists
Slovenian: ANTAGONISTI ADRENERGIČNIH RECEPTORJEV ALFA-1
English: Ask your pharmacist for an oral syringe.
Slovenian: Glede brizge za peroralno dajanje se posvetujte s farmacevtom.