FrancophonIA/ELRC3.0 huggingface dataset:
English: It is important that you carry on receiving ABILIFY solution for injection for as long as your doctor has told you to.
Croatian: Važno je da nastavite primati ABILIFY otopinu za injekciju onoliko dugo koliko Vam je to rekao liječnik.
English: • reports of abnormal liver tests values,
Croatian: • abnormalne vrijednosti jetrenih pretraga,
English: PET-bottles with polypropylene child-resistant closure containing 50 mL, 150 mL or 480 mL per bottle.
Croatian: PET boce s polipropilenskim sigurnosnim zatvaračem za djecu koje sadrže 50 ml, 150 ml ili 480 ml po boci.
English: Care must be taken to avoid inadvertent injection of this medicinal product into a blood vessel.
Croatian: Nephodan je oprez kako bi se izbjegla nehotična injekcija ovog lijeka u krvnu žilu.
English: The safety and efficacy of ABILIFY solution for injection in children and adolescents aged 0 to 17 years have not been established.
Croatian: Sigurnost i djelotvornost lijeka ABILIFY otopina za injekciju u djece i adolescenata u dobi od 0 do 17 godina nisu ustanovljene.
English: ABILIFY is used to treat adults and adolescents aged 13 years and older who suffer from a condition with symptoms such as feeling "high", having excessive amounts of energy, needing much less sleep than usual, talking very quickly with racing ideas and sometimes severe irritability.
Croatian: ABILIFY se koristi za liječenje odraslih osoba te adolescenata u dobi od 13 godina i starijih koji boluju od stanja čiji su simptomi “povišeno” raspoloženje, pretjerana količina energije, potreba za manjom količinom sna nego obično, vrlo brz govor i ubrzan tijek misli te ponekad teška razdražljivost.
English: ABILIFY 1 mg/mL oral solution is a clear, colourless to light yellow liquid supplied in bottles with polypropylene child-resistant closure containing 50 mL, 150 mL or 480 mL per bottle.
Croatian: ABILIFY 1 mg/ml oralna otopina je bistra, bezbojna do svijetložuta tekućina u boci s polipropilenskim sigurnosnim zatvaračem za djecu koja sadrži 50 ml, 150 ml ili 480 ml po boci.
English: • low levels of blood platelets,
Croatian: • nizak broj krvnih pločica,
English: For single tablet removal, open the package and peel back the foil on the blister to expose the tablet.
Croatian: Da biste uzeli jednu tabletu, otvorite pakiranje i skinite foliju s blistera da biste razotkrili tabletu.
English: • heart attack,
Croatian: • srčani udar,
English: Other urges, reported, include: increased sexual urges, compulsive shopping, binge or compulsive eating, and other impulsive and compulsive behaviours.
Croatian: Drugi porivi koji su bili zabilježeni uključuju: pojačan seksualni poriv, kompulzivno kupovanje, kompulzivno prejedanje (engl. binge eating) te druga impulzivna ili kompulzivna ponašanja.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with ABILIFY in one or more subsets of the paediatric population in the treatment of schizophrenia and in the treatment of bipolar affective disorder (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove odgodila je obvezu podnošenja rezultata ispitivanja lijeka ABILIFY u jednoj ili više podskupina pedijatrijske populacije u liječenju shizofrenije te u liječenju bipolarnog afektivnog poremećaja (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Potential for other medicinal products to affect ABILIFY solution for injection
Croatian: Potencijal drugih lijekova da utječu na ABILIFY otopinu za injekciju
English: Talk to your doctor before taking ABILIFY.
Croatian: Obratite se svom liječniku prije nego što uzmete ABILIFY.
English: • triptans (such as sumatriptan and zolmitripitan) used for treating migraine
Croatian: • triptani (kao što su sumatriptan i zolmitriptan) koji se primjenjuju za liječenje migrene.
English: The following symptoms may occur in newborn babies, of mothers that have used ABILIFY in the last trimester (last three months of their pregnancy): shaking, muscle stiffness and/or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding.
Croatian: Sljedeći simptomi se mogu javiti u novorođenčadi majki koje su uzimale ABILIFY u posljednjem tromjesečju (posljednja tri mjeseca trudnoće): tresavica, ukočenost i/ili slabost mišića, pospanost, uznemirenost, tegobe s disanjem i poteškoće s hranjenjem.
English: These medicines may increase the risk of side effects; if you get any unusual symptom taking any of these medicines together with ABILIFY, you should see your doctor.
Croatian: Ovi lijekovi mogu povećati rizik od nuspojava; ako dobijete ikakve neobične simptome dok uzimate neki od ovih lijekova zajedno s lijekom ABILIFY, trebate se obratiti liječniku.
English: Following a single oral dose of [14C]-labelled aripiprazole, approximately 27 % of the administered radioactivity was recovered in the urine and approximately 60 % in the faeces.
Croatian: Nakon jednokratne oralne doze aripiprazola obilježenog izotopom [14C], oko 27 % primijenjene radioaktivnosti pojavi se u mokraći, a oko 60 % u stolici.
English: Somnolence/sedation and extrapyramidal disorder were reported very commonly (≥ 1/10), and dry mouth, increased appetite, and orthostatic hypotension were reported commonly (≥ 1/100, < 1/10).
Croatian: Somnolencija/sedacija i ekstrapiramidni poremećaji bili su prijavljeni vrlo često (≥ 1/10), dok su često bili prijavljeni suha usta, pojačan apetit i ortostatska hipotenzija (≥ 1/100, < 1/10).
English: However, the estimation of the HR for the younger (13 to 14 years) group was not precise, reflecting the smaller number of subjects in that group (aripiprazole, n = 29; placebo, n = 12), and the confidence interval for this estimation (ranging from 0.151 to 1.628) did not allow conclusions to be drawn on the presence of a treatment effect.
Croatian: Međutim, procjena HR-a u mlađoj (u dobi od 13 do 14 godina) skupini nije bila precizna zbog manjeg broja ispitanika u toj skupini (aripiprazol, n = 29; placebo, n = 12), a interval pouzdanosti ove procjene (u rasponu od 0,151 do 1,628) nije dopustio donošenje zaključka o prisutnosti terapijskog učinka.
English: Your doctor will change your treatment to oral ABILIFY as soon as appropriate.
Croatian: Liječnik će Vam zamijeniti liječenje injekcijama oralnim liječenjem ABILIFY čim to bude moguće.
English: ABILIFY is ready to use.
Croatian: ABILIFY je spreman za primjenu.
English: • low levels of white blood cells,
Croatian: • nizak broj bijelih krvnih stanica,
English: < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000) and not known (cannot be estimated from the available data).
Croatian: često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (<10 000) i nepoznato (ne može se procijeniti iz dostupnih podataka).
English: ABILIFY is used to treat quickly symptoms of agitation and distressing behaviour that may occur in a disease characterised by symptoms such as:
Croatian: ABILIFYse koristi za brzo uklanjanje simptoma uznemirenosti i poremećenog ponašanja, koji se mogu javiti u bolesti karakteriziranoj simptomima kao što su:
English: What ABILIFY is and what it is used for What you need to know before you take ABILIFY How to take ABILIFY
Croatian: Što je ABILIFY i za što se koristi Što morate znati prije nego primite ABILIFY
English: • depression,
Croatian: • depresija,
English: These medicines may increase the risk of side effects or reduce the effect of ABILIFY; if you get any unusual symptom taking any of these medicines together with ABILIFY you should see your doctor.
Croatian: Ti lijekovi mogu povećati rizik od nuspojava ili smanjiti učinak lijeka ABILIFY; ako dobijete neki neobični simptom dok uzimate ove lijekove zajedno s lijekom ABILIFY, trebate se obratiti liječniku.
English: In a pooled analysis on lipid parameters from placebo controlled clinical trials in adults, aripiprazole has not been shown to induce clinically relevant alterations in levels of total cholesterol, triglycerides, High Density Lipoprotein (HDL) and Low Density Lipoprotein (LDL).
Croatian: U objedinjenoj analizi lipidnih parametara prikupljenih u placebom kontroliranim ispitivanjima u odraslih bolesnika nije se pokazalo da aripiprazol izaziva klinički značajne promjene razine ukupnog kolesterola, triglicerida, lipoproteina visoke gustoće (HDL-a) i lipoproteina male gustoće (LDL-a).
English: • certain medicines to treat HIV infection (such as efavirenz, nevirapine, an protease inhibitors e.g. indinavir, ritonavir)
Croatian: • određene lijekove za liječenje HIV-infekcije (kao što su efavirenz, nevirapin, inhibitori proteaze, npr. indinavir, ritonavir)
English: At steady state, dehydro-aripiprazole, the active metabolite, represents about 40 % of aripiprazole AUC in plasma.
Croatian: U stanju dinamičke ravnoteže, dehidro-aripiprazol, djelatni metabolit aripiprazola, čini oko 40 % AUC-a aripiprazola u plazmi.
English: Quinidine and other CYP2D6 inhibitors
Croatian: Kinidin i drugi inhibitori CYP2D6
English: Tablet disintegration occurs rapidly in saliva.
Croatian: Tableta se u slini brzo raspada.
English: The recommended dose is 9.75 mg (1.3 mL) for the first injection.
Croatian: Preporučena doza je 9,75 mg (1,3 ml) u prvoj injekciji.
English: Patients who have been given too much aripiprazole have experienced the following symptoms:
Croatian: Bolesnici kojima se dalo previše aripiprazola imali su sljedeće simptome:
English: At equivalent doses, the peak plasma concentrations of aripiprazole (Cmax) from the solution were somewhat higher but the systemic exposure (AUC) was equivalent to tablets.
Croatian: Pri ekvivalentnim su dozama vršne koncentracije aripiprazola u plazmi (Cmax) nakon primjene otopine bile nešto više, ali je sistemska izloženost (AUC) bila jednaka onoj kod primjene tableta.
English: However your doctor may prescribe a lower or higher dose to a maximum of 30 mg once a day.
Croatian: Međutim, liječnik Vam može propisati nižu ili višu dozu, koja smije iznositi maksimalno 30 mg jedanput dnevno.
English: Irritability associated with autistic disorder: the safety and efficacy of ABILIFY in children and adolescents aged below 18 years have not yet been established.
Croatian: Razdražljivost povezana s autističnim poremećajem: Sigurnost i djelotvornost lijeka ABILIFY u djece i adolescenata mlađih od 18 godina nisu još ustanovljene.
English: In this trial, patients were assigned by investigators with either open-label lithium or valproate monotherapy to determine partial non-response.
Croatian: bolesnicima su ispitivači dodijelili otvorenu monoterapiju litijem ili valproatom da se utvrdi djelomičan izostanak odgovora.
English: If parenteral benzodiazepine therapy is deemed necessary in addition to aripiprazole solution for injection, patients should be monitored for excessive sedation and for orthostatic hypotension (see section 4.5).
Croatian: Ako se smatra da je neophodno primijeniti parenteralnu terapiju benzodiazepinima dodatno uz aripiprazol u otopini za injekciju, bolesnike se mora nadzirati zbog moguće pojave pretjerane sedacije i ortostatske hipotenzije (vidjeti dio 4.5).
English: Management of overdose should concentrate on supportive therapy, maintaining an adequate airway, oxygenation and ventilation, and management of symptoms.
Croatian: Zbrinjavanje predoziranja Zbrinjavanje predoziranja mora se usmjeriti na suportivnu terapiju, održavanje prohodnosti dišnih puteva, oksigenaciju i ventilaciju te zbrinjavanje simptoma.
English: • hiccups.
Croatian: • štucavica.
English: • speech disorder,
Croatian: • poremećaj govora,
English: The singledose pharmacokinetics of aripiprazole was linear and dose-proportional.
Croatian: Farmakokinetika aripiprazola nakon primjene jedne doze bila je linearna i proporcionalna dozi.
English: Patients treated with any antipsychotics, including aripiprazole, should be observed for signs and symptoms of hyperglycaemia (such as polydipsia, polyuria, polyphagia and weakness) and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control (see section 4.8).
Croatian: Bolesnici liječeni bilo kojim antipsihoticima, uključujući aripiprazol, moraju se motriti zbog moguće pojave znakova i simptoma hiperglikemije (kao što su polidipsija, poliurija, polifagija i slabost), a bolesnici sa šećernom bolešću ili rizičnim čimbenicima za šećernu bolest moraju se redovito kontrolirati zbog mogućeg pogoršanja regulacije glukoze (vidjeti dio 4.8).
English: extrapyramidal disorder (18.4 %), akathisia (16.0 %), and fatigue (11.8 %); and commonly (≥ 1/100, < 1/10) abdominal pain upper, heart rate increased, weight increased, increased appetite, muscle twitching, and dyskinesia.
Croatian: ekstrapiramidni poremećaj (18,4 %), akatizija (16,0 %) i umor (11,8 %); te često (≥ 1/100, < 1/10) bol u gornjem dijelu abdomena, ubrzan srčani ritam, povećanje tjelesne težine, pojačan tek, trzanje mišića i diskinezija.
English: Outer carton: abilify 1 mg/mL
Croatian: Vanjsko pakiranje: abilify 1 mg/ml
English: The rate of death in aripiprazoletreated patients was 3.5 % compared to 1.7 % in the placebo group.
Croatian: Stopa smrti u bolesnika liječenih aripiprazolom bila je 3,5 % u usporedbi s 1,7 % u onih koji su primali placebo.
English: Kaplan-Meier relapse rates at week 16 were 35 % for aripiprazole and 52 % for placebo; the hazard ratio for relapse within 16 weeks (aripiprazole/placebo) was 0.57 (non-statistically significant difference).
Croatian: Kaplan-Meierova stopa relapsa u 16. tjednu za bolesnike na aripiprazolu iznosila je 35 % dok je za one na placebu bila 52 %; omjer hazarda relapsa u tih 16 tjedana (aripiprazol/placebo) bio je 0,57 (nije statistički značajna razlika).
English: Aripiprazole doses ranging from 0.5 mg to 30 mg administered once a day to healthy subjects for 2 weeks produced a dose-dependent reduction in the binding of 11C-raclopride, a D2/D3 receptor ligand, to the caudate and putamen detected by positron emission tomography.
Croatian: Doze aripiprazola u rasponu od 0,5 mg do 30 mg primijenjene jedanput dnevno u zdravih ispitanika tijekom 2 tjedna proizvele su o dozi ovisno smanjenje vezivanja 11C-rakloprida, liganda D2/D3 receptora, u nukleus caudatusu i putamenu, kako se pokazalo pozitronskom emisijskom tomografijom.
English: Taking ABILIFY with some medicines may mean the doctor will need to change your dose of ABILIFY or the other medicines.
Croatian: Uzimanje lijeka ABILIFY s nekim lijekovima može značiti da će Vam liječnik morati promijeniti dozu lijeka ABILIFY ili tih drugih lijekova.
English: 14 × 1 tablets 28 × 1 tablets 49 × 1 tablets 56 × 1 tablets 98 × 1 tablets
Croatian: 14 × 1 tableta 28 × 1 tableta 49 × 1 tableta 56 × 1 tableta 98 × 1 tableta
English: Aripiprazole exhibited high binding affinity in vitro for dopamine D2 and D3, serotonin 5-HT1A and 5-HT2A receptors and moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha-1 adrenergic and histamine H1 receptors.
Croatian: Aripiprazol je in vitro pokazao visok afinitet vezanja za dopaminske D2 i D3, serotoninske 5-HT1A i 5-HT2A receptore i umjeren afinitet za dopaminske D4, serotoninske 5-HT2C i 5-HT7, alfa-1 adrenergičke i histaminske H1
English: Receiving ABILIFY with some medicines may mean the doctor will need to change your dose of ABILIFY or the other medicines.
Croatian: Primanje lijeka ABILIFY s nekim lijekovima može značiti da će Vam liječnik morati promijeniti dozu lijeka ABILIFY ili tih drugih lijekova.
English: After a 13 to 26-week stabilisation on aripiprazole (2 mg/day to 15 mg/day) patients with a stable response were either maintained on aripiprazole or substituted to placebo for further 16 weeks.
Croatian: Nakon stabiliziranja stanja na aripiprazolu (2 mg/dan do 15 mg/dan) tijekom 13 do 26 tjedana, bolesnici sa stabilnim odgovorom sljedećih su 16 tjedana održavani na aripiprazolu ili su prebačeni na placebo.
English: ABILIFY is effective in a dose range of 10 mg/day to 30 mg/day.
Croatian: ABILIFY je učinkovit u rasponu doza od 10 mg/dan do 30 mg/dan.
English: • a fall in blood pressure on standing up which causes dizziness, light-headedness or fainting,
Croatian: • pad krvnog tlaka pri ustajanju koji uzrokuje omaglicu, ošamućenost ili nesvjesticu,
English: Aripiprazole is widely distributed throughout the body with an apparent volume of distribution of 4.9 L/kg, indicating extensive extravascular distribution.
Croatian: Aripiprazol se opsežno raspodjeljuje po cijelom tijelu uz prividan volumen raspodjele od 4,9 l/kg, koji ukazuje na opsežnu ekstravaskularnu raspodjelu.
English: Uncommon side effects (may affect up to 1 in 100 people):
Croatian: Manje česte nuspojave (mogu se javiti od 1 na 100 osoba):
English: The oral solution contains methyl parahydroxybenzoate and propyl parahydroxybenzoate.
Croatian: Oralna otopina sadrži metilparahidroksibenzoat i propilparahidroksibenzoat.
English: This medicine can be given regardless of meals.
Croatian: Ovaj se lijek može primjenjivati neovisno o obrocima.
English: Schizophrenia in adolescents aged 15 years and older In a short-term placebo-controlled clinical trial involving 302 adolescents (13 to 17 years) with schizophrenia, the frequency and type of adverse reactions were similar to those in adults except for the following reactions that were reported more frequently in adolescents receiving aripiprazole than in adults receiving aripiprazole (and more frequently than placebo):
Croatian: Shizofrenija u adolescenata u dobi od 15 godina i starijih U kratkotrajnom placebom kontroliranom kliničkom ispitivanju u kojem su sudjelovala 302 adolescenta (13 do 17 godina) sa shizofrenijom, učestalost i vrsta nuspojava bile su slične onima u odraslih, osim što su sljedeće nuspojave bile prijavljene češće u adolescenata koji su primali aripiprazol nego u odraslih koji su primali aripiprazol (i češće nego uz placebo):
English: Patients with attention deficit hyperactivity disorder (ADHD) comorbidity
Croatian: Bolesnici s popratnim poremećajem hiperaktivnosti i deficita pažnje (ADHD)
English: Tics associated with Tourette's disorder: the safety and efficacy of ABILIFY in children and adolescents 6 to 18 years of age have not yet been established.
Croatian: Tikovi povezani s Touretteovim poremećajem: Sigurnost i djelotvornost lijeka ABILIFY u djece i adolescenata u dobi od 6 do 18 godina nisu još ustanovljene.
English: • increased blood levels of the hormone prolactin,
Croatian: • povišene razine hormona prolaktina u krvi,
English: Removal of the intact orodispersible tablet from the mouth is difficult.
Croatian: Raspadljivu tabletu za usta teško je iz usta izvaditi neoštećenu.
English: Since patients treated with antipsychotics often present with acquired risk factors for VTE, all possible risk factors for VTE should be identified before and during treatment with aripiprazole and preventive measures undertaken.
Croatian: Budući da bolesnici liječeni antipsihoticima često već imaju stečene čimbenike rizika za VTE, prije i tijekom liječenja aripiprazolom moraju se utvrditi svi mogući čimbenici rizika za VTE i poduzeti preventivne mjere.
English: • acute confusion, seizures (epilepsy), coma, a combination of fever, faster breathing, sweating,
Croatian: • akutnu smetenost, napadaje (epilepsiju), komu, kombinaciju vrućice, ubrzanog disanja,
English: Treatment should be initiated at 2 mg (using ABILIFY oral solution 1 mg/mL) for 2 days, titrated to 5 mg for 2 additional days to reach the recommended daily dose of 10 mg.
Croatian: Liječenje se mora započeti dozom od 2 mg (koristeći ABILIFY oralnu otopinu 1 mg/ml) tijekom prva 2 dana, a potom titrirati do 5 mg tijekom sljedeća 2 dana kako bi se postigla preporučena dnevna doza od 10 mg.
English: Oral solution 50 mL oral solution 150 mL oral solution 480 mL oral solution
Croatian: Oralna otopina 50 ml oralne otopine 150 ml oralne otopine 480 ml oralne otopine
English: ABILIFY solution for injection should not be administered intravenously or subcutaneously.
Croatian: ABILIFY otopina za injekciju ne smije se primijeniti intravenski niti supkutano.
English: • muscle stiffness, and drowsiness or sleepiness, slower breathing, choking, high or low blood pressure, abnormal rhythms of the heart.
Croatian: • ukočenosti mišića i omamljenosti ili pospanosti, usporeno disanje, gušenje, visok ili nizak krvni tlak, abnormalni srčani ritam.
English: Patients were 6 to 18 years and presented an average score of 29 on TTS-YGTSS at baseline.
Croatian: 6 do 18 godina i imali su prosječno 29 bodova na ljestvici TTS-YGTSS na početku ispitivanja.
English: The recommended initial dose for ABILIFY solution for injection is 9.75 mg (1.3 mL), administered as a single intramuscular injection.
Croatian: Doziranje Preporučena početna doza ABILIFY otopine za injekciju je 9,75 mg (1,3 ml) primijenjena u obliku jednokratne intramuskularne injekcije.
English: Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
Croatian: Unutar svake skupine učestalosti nuspojave su prikazane slijedom prema opadajućoj ozbiljnosti.
English: The aripiprazole AUC in the first 2 hours after an intramuscular injection was 90 % greater than the AUC after the same dose as a tablet; systemic exposure was generally similar between the 2 formulations.
Croatian: AUC aripiprazola u prva 2 sata nakon intramuskularne injekcije bila je 90 % veća od AUC-a nakon iste doze primijenjene u obliku tablete;
English: The recommended dose for adults is 15 mL solution (corresponding to 15 mg aripiprazole) once a day.
Croatian: Preporučena doza za odrasle je 15 ml otopine (što odgovara 15 mg aripiprazola) jedanput dnevno.
English: Other strong inhibitors of CYP3A4, such as itraconazole and HIV protease inhibitors may be expected to have similar effects and similar dose reductions should therefore be applied (see section 4.2).
Croatian: Slični učinci mogu se očekivati i od drugih jakih inhibitora CYP3A4, kao što su itrakonazol i inhibitori HIV proteaze pa se stoga moraju provesti slična smanjenja doze (vidjeti dio 4.2).
English: However, the oral solution should not be diluted with other liquids or mixed with any food prior to administration.
Croatian: Međutim, oralna se otopina ne smije razrjeđivati drugim tekućinama niti miješati s hranom prije primjene.
English: Use in children and adolescents The recommended dose for adolescents is 10 mL solution (corresponding to 10 mg aripiprazole)
Croatian: Primjena u djece i adolescenata Preporučena doza za adolescente je 10 ml otopine (što odgovara 10 mg aripiprazola) jedanput dnevno.
English: Also contains sulfobutylether b-cyclodextrin, tartaric acid, sodium hydroxide, and water for injections.
Croatian: Također sadrži: sulfobutileter β-ciklodekstrin, tartaratnu kiselinu, natrijev hidroksid i vodu za injekcije.
English: Allergic reaction (e.g. anaphylactic reaction, angioedema including swollen tongue, tongue oedema, face oedema, pruritus allergic, or urticaria)
Croatian: anafilaktička reakcija, angioedem uključujući otečen jezik, edem jezika, edem lica, alergijski svrbež i urtikariju)
English: In the placebocontrolled trials, the mean weight gain was 0.4 kg for placebo and 1.6 kg for aripiprazole.
Croatian: U placebom kontroliranim ispitivanjima srednja vrijednost povećanja tjelesne težine iznosila je 0,4 kg u skupinama koje su primale placebo i 1,6 kg u skupinama koje su primale aripiprazol.
English: In a 60- to 89-week, randomised, double-blind, placebo-controlled trial in adolescent subjects (n = 146; ages 13 to 17 years) with schizophrenia, there was a statistically significant difference in the rate of relapse of psychotic symptoms between the aripiprazole (19.39 %) and placebo (37.50 %) groups.
Croatian: U randomiziranom, dvostruko slijepom, placebom kontroliranom ispitivanju u trajanju od 60 do 89 tjedana u adolescentnih ispitanika (n = 146; u dobi od 13 do 17 godina) sa shizofrenijom postojala je statistički značajna razlika u stopi relapsa psihotičnih simptoma između skupine koja je primala aripiprazol (19,39%) i skupine koja je primala placebo (37,50%).