FrancophonIA/ELRC3.0 huggingface dataset:
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each prolonged-release tablet contains 375 mg ranolazine.
Slovenian: NAVEDBA ENE ALI VEČ ZDRAVILNIH UČINKOVIN Ena tableta s podaljšanim sproščanjem vsebuje 375 mg ranolazina.
English: In rats, no effects in fetuses was noted when mothers were exposed to 2-fold greater levels (AUC) than expected in humans, whereas decreased fetal weight and reduced ossification were observed when the exposure of mothers was 7.5-fold than those obtained in humans.
Slovenian: Na zarodkih ni bilo opaženih učinkov po izpostavljenosti (AUC) z 2-krat večjimi vrednostmi ranolazina na brejih podganah kot je predvidena za človeka.
English: NAME OF THE MEDICINAL PRODUCT Ranexa 750 mg prolonged-release tablets
Slovenian: IME ZDRAVILA Ranexa 750 mg tablete s podaljšanim sproščanjem
English: Ranexa 1000 mg twice daily increased plasma concentrations of simvastatin lactone, simvastatin acid by about 2 fold.
Slovenian: Odmerek zdravila Ranexa 1000 mg dvakrat na dan je za 2 -krat povečal plazemsko koncentracijo simvastatinovega laktona in simvastatinove kisline.
English: Renal and urinary disorders Uncommon: dysuria, haematuria, chromaturia.
Slovenian: Občasni: disurija, hematurija, kromaturija.
English: Eight-hundred and twenty-three patients (23% women) were randomised to receive 12 weeks of treatment with Ranexa 750 mg twice daily, 1000 mg twice daily, or placebo.
Slovenian: V osrednji študiji CARISA so zdravilo Ranexa dodali zdravljenju z atenololom v odmerku 50 mg enkrat na dan, amlodipinom v odmerku 5 mg enkrat na dan ali diltiazemom v odmerku 180 mg enkrat na dan. 823 bolnikov (23% žensk) so naključno razdelili tako, da so 12 tednov dvakrat na dan prejemali 750 mg ali 1000 mg zdravila Ranexa ali placebo.
English: Ranexa 1000 mg twice daily increased plasma concentrations of simvastatin lactone, simvastatin acid, by about 2-fold.
Slovenian: Odmerek zdravila Ranexa 1000 mg dvakrat na dan je za 2- krat povečal plazemsko koncentracijo simvastatinovega laktona in simvastatinove kisline.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each prolonged-release tablet contains 500 mg ranolazine.
Slovenian: NAVEDBA ENE ALI VEČ ZDRAVILNIH UČINKOVIN Ena tableta s podaljšanim sproščanjem vsebuje 500 mg ranolazina.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each prolonged-release tablet contains 750 mg ranolazine.
Slovenian: NAVEDBA ENE ALI VEČ ZDRAVILNIH UČINKOVIN Ena tableta s podaljšanim sproščanjem vsebuje 750 mg ranolazina.
English: Headache
Slovenian: Serija
English: NAME OF THE MEDICINAL PRODUCT Ranexa 500 mg prolonged-release tablets Ranolazine
Slovenian: Ranexa 500 mg tablete s podaljšanim sproščanjem ranolazin
English: NAME OF THE MEDICINAL PRODUCT Ranexa 750 mg prolonged-release tablets Ranolazine
Slovenian: Ranexa 750 mg tablete s podaljšanim sproščanjem ranolazin
English: NAME OF THE MEDICINAL PRODUCT Ranexa 375 mg prolonged-release tablets Ranolazine
Slovenian: Ranexa 375 mg tablete s podaljšanim sproščanjem ranolazin
English: - If you get any side effects talk to your doctor.
Slovenian: - Če opazite kateri koli neželeni učinek, se posvetujte s svojim zdravnikom ali s farmacevtom.
English: Careful dose titration of Ranexa is recommended in patients treated with diltiazem and other moderately potent CYP3A4 inhibitors (e.g. erythromycin, fluconazole).
Slovenian: Pri bolnikih, ki jemljejo diltiazem in druge zmerno močne zaviralce encima CYP3A4 (npr. eritromicin, flukonazol), je priporočeno odmerek zdravila Ranexa titrirati previdno.
English: You must talk to a doctor if you do not feel better or if you feel worse.
Slovenian: Če se znaki vaše bolezni poslabšajo ali ne izboljšajo, se posvetujte s svojim zdravnikom.
English: There is a lower need for precautions in patients with CYP2D6 EM status.
Slovenian: Pri dobrih presnavljavcih CYP2D6 je potreba po previdnostnih ukrepih manjša.
English: Talk to your doctor before taking Ranexa: - if you have mild or moderate kidney problems.
Slovenian: Pred začetkom jemanja zdravila Ranexa se posvetujte s svojim zdravnikom: - če imate blage ali zmerne težave z ledvicami; - če imate blage težave z jetri; - če ste kadar koli imeli nenormalen elektrokardiogram (EKG); - če ste starejši; - če imate majhno telesno maso (60 kg ali manj); - če imate srčno popuščanje.
English: Altered sensation
Slovenian: Bolezni prebavil
English: Using other medicines and Ranexa
Slovenian: Shranjevanje zdravila RANEXA
English: - medicines to treat epilepsy or another neurologic disorder (e.g. phenytoin, carbamazepine, or phenobarbital); are taking rifampicin for an infection (e.g. tuberculosis); or are taking the herbal remedy St. John's Wort, as these medicines may cause Ranexa to be less effective.
Slovenian: Zdravnik se bo morda odločil, da vam da manjši odmerek; - zdravila za zdravljenje epilepsije ali drugih nevroloških bolezni (npr. fenitoin, karbamazepin ali fenobarbital); če jemljete rifampicin za zdravljenje okužbe (npr. tuberkuloze) ali če jemljete zeliščni pripravek iz šentjanževke, saj ta zdravila lahko zmanjšajo učinkovitost zdravila Ranexa; - zdravila za srce, ki vsebujejo digoksin ali metoprolol, ker bo zdravnik morda spremenil odmerek teh zdravil med jemanjem zdravila Ranexa; - nekatera zdravila za zdravljenje alergij (npr. terfenadin, astemizol, mizolastin), motenj srčnega ritma (npr. disopiramid, prokainamid) in depresije (npr. imipramin, doksepin ali amitriptilin), saj ta zdravila lahko vplivajo na vaš EKG; - nekatera zdravila za zdravljenje depresije (bupropion), psihoze, okužbe z virusom HIV (efavirenz) ali raka (ciklofosfamid); - nekatera zdravila za zdravljenje visokih vrednosti holesterola v krvi (npr. simvastatin, lovastatin, atorvastatin).
English: Muscle weakness.
Slovenian: Poročali so tudi o: mišični slabosti.
English: General disorders and administration site conditions Common: asthenia.
Slovenian: Splošne težave in spremembe na mestu aplikacije Pogosti: astenija.
English: Dose limitation of other statins, metabolised by CYP3A4 (e.g. lovastatin), may be considered when taking Ranexa.
Slovenian: Morda bo pri jemanju zdravila Ranexa potrebno razmisliti o omejitvi odmerkov ostalih statinov, ki se presnavljajo z encimom CYP3A4 (npr. lovastatin).
English: Vascular disorders
Slovenian: Žilne bolezni
English: GENERAL CLASSIFICATION FOR SUPPLY Medicinal product subject to medical prescription
Slovenian: DATUM IZTEKA ROKA UPORABNOSTI ZDRAVILA Uporabno do
English: Not known (frequency cannot be estimated from the available data):
Slovenian: Pogostnost neznana (je ni mogoče oceniti iz razpoložljivih podatkov):
English: Other side effects may include:
Slovenian: Drugi neželeni učinki lahko vključujejo:
English: If you experience these symptoms, do not drive or use tools or machines.
Slovenian: Če pride do teh simptomov, ne vozite in ne uporabljajte orodja ali strojev.
English: Shock (including cardiogenic shock).
Slovenian: Šok (vključno s kardiogenim šokom).
English: Volume of distribution is approximately 21 l/kg.
Slovenian: Volumen porazdelitve je približno 21 l/kg.
English: Some side effects can be serious and need immediate medical attention.
Slovenian: Nekateri neželeni učinki so lahko resni in zahtevajo takojšnjo zdravstveno oskrbo.
English: (It is also recommended to avoid Dafiro HCT in early pregnancy - see Pregnancy section.)
Slovenian: (Priporočeno je, da se zdravilu Dafiro HCT izogibate tudi v zgodnji nosečnosti - glejte poglavje Nosečnost.)
English: The apparent volume of distribution is 4-8 l/kg.
Slovenian: Navidezni volumen porazdelitve je 4-8 l/kg.
English: Date of first authorisation: 04 November 2009 Date of latest renewal: 04 July 2014
Slovenian: Datum zadnjega podaljšanja: 4. julij 2014
English: Valsartan shows multiexponential decay kinetics (t½α <1 h and t½ß about 9 h).
Slovenian: Valsartan kaže multieksponentno kinetiko upadanja (t½α <1 uro in t½ß približno 9 ur).
English: • palpitations (awareness of your heart beat)
Slovenian: • palpitacije (zavedanje bitja vašega srca)
English: • swelling of the tongue and throat which causes great difficulty breathing
Slovenian: • otekanje jezika in grla, ki zelo oteži dihanje
English: Severe hypotension.
Slovenian: Huda hipotenzija.
English: As for any combination containing three active substances, side effects associated with each individual component cannot be excluded.
Slovenian: Kot pri vsaki kombinaciji, ki vsebuje tri učinkovine, ni mogoče izključiti neželenih učinkov, ki so povezani s posameznimi sestavinami.
English: * See section 4.4 Photosensitivity ** Mostly consistent with cholestasis
Slovenian: * glejte poglavje 4.4 Fotosenzitivnost ** o tem so najpogosteje poročali v povezavi s holestazo
English: • disorders combining rigidity, tremor and/or movement disorders
Slovenian: • motnje, ki združujejo okorelost, tremor in/ali motnje gibanja
English: Amlodipine can have mild or moderate influence on the ability to drive and use machines.
Slovenian: Amlodipin ima lahko blag do zmeren vpliv na sposobnost vožnje in upravljanja strojev.
English: • ACE inhibitors or aliskiren -(see also information under the headings “Do not take Dafiro HCT” and “Warnings and precautions”) .
Slovenian: • zaviralcev ACE ali aliskirena (glejte tudi informacije pod naslovoma “Ne jemljite zdravila Dafiro HCT” in “Opozorila in previdnostni ukrepi”).
English: Do not take Dafiro HCT if you are more than 3 months pregnant.
Slovenian: Ne jemljite zdravila Dafiro HCT če ste noseči več kot 3 mesece.
English: The absorption of hydrochlorothiazide, after an oral dose, is rapid (Tmax about 2 hours).
Slovenian: Absorpcija hidroklorotiazida po zaužitju je hitra (tmax približno 2 uri).
English: Your doctor will normally advise you to stop taking Dafiro HCT before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Dafiro HCT.
Slovenian: Zdravnik vam bo praviloma svetoval, da prenehate z jemanjem zdravila Dafiro HCT še preden zanosite oziroma takoj, ko ugotovite, da ste noseči in vam bo svetoval jemanje drugega zdravila namesto zdravila Dafiro HCT.
English: Dafiro HCT was studied in a double-blind, active controlled study in hypertensive patients.
Slovenian: Zdravilo Dafiro HCT so proučevali v dvojno slepi, aktivno kontrolirani študiji pri bolnikih s hipertenzijo.
English: No information is available regarding the use of valsartan during breast-feeding.
Slovenian: Ni podatkov o uporabi valsartana med dojenjem.
English: As with all other vasodilators, special caution is indicated in patients with mitral stenosis or significant aortic stenosis that is not high grade.
Slovenian: Tako kot pri vseh vazodilatatorjih, je posebna previdnost potrebna pri bolnikih z mitralno stenozo ali s pomembno aortno stenozo, ki sicer ni močno izražena.
English: Biotransformation Hydrochlorothiazide is eliminated predominantly as unchanged compound.
Slovenian: Biotransformacija Hidroklorotiazid se večinoma izloča v obliki nespremenjene učinkovine.
English: Uncommon (may affect up to 1 in 100 people): • severely decreased urine output (decreased kidney function)
Slovenian: Občasni (pojavijo se pri največ 1 od 100 bolnikov): • zelo zmanjšano izločanje urina (zmanjšano delovanje ledvic)
English: Elderly people (age 65 years and older)
Slovenian: Starejši ljudje (stari 65 let in več)
English: Patients taking Dafiro HCT and driving vehicles or using machines should take into account that dizziness or weariness may occasionally occur.
Slovenian: Bolniki, ki jemljejo zdravilo Dafiro HCT in vozijo motorna vozila ali uporabljajo stroje, morajo upoštevati, da se lahko občasno pojavi omotica ali utrujenost.
English: In this active controlled clinical trial, the most common reasons for discontinuation of therapy with Dafiro HCT were dizziness and hypotension (0.7%).
Slovenian: V tem aktivno kontroliranem kliničnem preskušanju sta bila najbolj pogosta razloga za prekinitev zdravljenja z zdravilom Dafiro HCT omotičnost in hipotenzija (0,7 %).
English: The European Medicines Agency has waived the obligation to submit the results of studies with Dafiro HCT in all subsets of the paediatric population in essential hypertension (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Dafiro HCT za vse podskupine pediatrične populacije z esencialno hipertenzijo (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: Consult a doctor immediately if you experience any of the following serious side effects after taking this medicine:
Slovenian: Takoj se posvetujte z zdravnikom, če po jemanju tega zdravila opazite katerega od naslednjih resnih neželenih učinkov:
English: Approximate size: 15 mm (length) x 5.9 mm (width).
Slovenian: Približna velikost: 15 mm (dolžina) x 5,9 mm (širina).
English: Biotransformation Amlodipine is extensively (approximately 90%) metabolised in the liver to inactive metabolites.
Slovenian: Biotransformacija Amlodipin se v jetrih v veliki meri (približno 90 %) presnovi v neaktivne presnovke.
English: These could be symptoms of an increase of pressure in your eye and can happen within hours to a week of taking Dafiro HCT.
Slovenian: To sta lahko simptoma povečanega tlaka v očesu in se lahko pojavita v nekaj urah do enega tedna jemanja zdravila Dafiro HCT.
English: Other anti-hypertensive medicinal products
Slovenian: druga antihipertenzivna zdravila
English: Dafiro HCT is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Slovenian: Jemanje zdravila Dafiro HCT v zgodnjem obdobju nosečnosti ni priporočljivo, če pa ste noseči več kot 3 mesece, ga ne smete jemati, ker lahko uporaba po tretjem mesecu nosečnosti povzroči resno škodo vašemu otroku.
English: The usual dose of Dafiro HCT is one tablet per day.
Slovenian: Običajni odmerek zdravila Dafiro HCT je ena tableta na dan.
English: However, it is important to take into account that Dafiro HCT may increase the hypotensive effect of other antihypertensive agents.
Slovenian: Pomembno pa je upoštevati, da zdravilo Dafiro HCT lahko okrepi hipotenzivno delovanje drugih antihipertenzivnih zdravil.
English: Valsartan is not transformed to a high extent as only about 20% of dose is recovered as metabolites.
Slovenian: Valsartan se ne spremeni v veliki meri, kajti le okrog 20 % odmerka se pojavi v obliki presnovkov.
English: The recommended dose of Dafiro HCT is one tablet per day, to be taken preferably in the morning.
Slovenian: Priporočeni odmerek zdravila Dafiro HCT je ena tableta na dan, ki jo je najbolje vzeti zjutraj.
English: • sneezing/runny nose caused by inflammation of the lining of the nose (rhinitis)
Slovenian: • kihanje/izcedek iz nosu zaradi vnetja nosne sluznice (rinitis)
English: • sensitivity to light
Slovenian: • občutljivost na svetlobo
English: See also information under the heading “Do not take Dafiro HCT”.
Slovenian: Glejte tudi informacije pod naslovom “Ne jemljite zdravila Dafiro HCT”.
English: Approximate size: 19 mm (length) x 7.5 mm (width).
Slovenian: Približna velikost: 19 mm (dolžina) x 7,5 mm (širina).
English: Upon co-administration of known inducers of the CYP3A4, the plasma concentration of amlodipine may vary.
Slovenian: Ob sočasnem dajanju znanih induktorjev CYP3A4 se plazemska koncentracija amlodipina lahko spreminja.
English: There is no relevant use of Dafiro HCT in the paediatric population (patients below age 18 years) for the indication of essential hypertension.
Slovenian: Zdravilo Dafiro HCT ni namenjeno za uporabo pri pediatrični populaciji (pri bolnikih, mlajših od 18 let) za indikacijo esencialne hipertenzije.
English: if you are taking any of the following medicines used to treat high blood pressure: an ACE inhibitor (for example enalapril, lisinopril, ramipril), in particular if you have diabetes-related kidney problems.
Slovenian: če jemljete katero od naslednjih zdravil, ki se uporabljajo za zdravljenje visokega krvnega tlaka: zaviralec ACE (na primer enalapril, lizinopril ali ramipril), zlasti če imate kakšne težave z ledvicami, ki so povezane s sladkorno boleznijo.
English: Anticholinergic agents and other medicinal products affecting gastric motility
Slovenian: antiholinergične učinkovine in druga zdravila, ki vplivajo na motiliteto želodca
English: The steady-state volume of distribution of valsartan after intravenous administration is about 17 litres, indicating that valsartan does not distribute into tissues extensively.
Slovenian: Volumen porazdelitve valsartana v stanju dinamičnega ravnovesja je po intravenski uporabi okrog 17 litrov, kar kaže, da se valsartan v tkiva ne porazdeli v veliki meri.
English: • decreased number of white blood cells
Slovenian: • znižanje števila belih krvnih celic
English: • liver enzyme increase which may have an effect on some medical tests
Slovenian: • zvišanje ravni jetrnih encimov, kar se lahko pokaže pri nekaterih laboratorijskih preiskavah
English: • mood changes
Slovenian: • spremembe razpoloženja
English: What Dafiro HCT is and what it is used for
Slovenian: Kaj je zdravilo Dafiro HCT in za kaj ga uporabljamo
English: Caution is indicated in long-term administration of these medicinal products.
Slovenian: Pri dolgotrajni uporabi teh zdravil je potrebna previdnost.
English: Hypersensitivity to the active substances, to other sulphonamide derivatives, to dihydropyridine derivatives, or to any of the excipients listed in section 6.1.
Slovenian: Preobčutljivost na učinkovine, druge sulfonamidne derivate, dihidropiridinske derivate ali katero koli pomožno snov, navedeno v poglavju 6.1.
English: Pharmacotherapeutic group: Agents acting on the renin-angiotensin system, angiotensin II antagonists, other combinations, ATC code: C09DX01.
Slovenian: Farmakoterapevtska skupina: zdravila z delovanjem na renin-angiotenzinski sistem, antagonisti angiotenzina II, druge kombinacije, oznaka ATC: C09DX01.
English: 70x1 film-coated tablets.
Slovenian: 70x1 filmsko obložena tableta.
English: • blistering skin (sign of a condition called dermatitis bullous)
Slovenian: • pojavljanje mehurjev na koži (znak bolezni, ki jo imenujemo bulozni dermatitis)
English: Some of these patients previously experienced angioedema with other medicinal products including ACE inhibitors.
Slovenian: Pri nekaterih od teh bolnikov je do angioedema prišlo že prej pri jemanju drugih zdravil; med drugim pri jemanju zaviralcev ACE.
English: Do not take Dafiro HCT with grapefruit or grapefruit juice.
Slovenian: Zdravila Dafiro HCT ne zaužijte skupaj z grenivko ali z grenivkinim sokom.
English: Children and adolescents The use of Dafiro HCT in children and adolescents under 18 years of age is not recommended.
Slovenian: Otroci in mladostniki Pri otrocih in mladostnikih, ki so stari manj kot 18 let, uporaba zdravila Dafiro HCT ni priporočena.
English: Dafiro HCT is available in packs containing 14, 28, 30, 56, 90, 98 or 280 film-coated tablets, in multipacks of 280 tablets (comprising 4 cartons, each containing 70 tablets, or 20 cartons, each containing 14 tablets), and in hospital packs containing 56, 98 or 280 tablets in single perforated dose blisters.
Slovenian: Tablete Dafiro HCT so na voljo v pakiranjih, ki vsebujejo 14, 28, 30, 56, 90, 98 ali 280 filmsko obloženih tablet, v skupnih pakiranjih z 280 tabletami (vsebujejo 4 škatle, od katerih vsaka vsebuje po 70 tablet ali 20 škatel, od katerih vsaka vsebuje po 14 tablet), in v bolnišničnih pakiranjih, ki vsebujejo 56, 98 ali 280 tablet v perforiranih pretisnih omotih za enkratni odmerek.
English: To date there is no experience of the safe use of Dafiro HCT in patients who have had a recent kidney transplantation.
Slovenian: Doslej ni izkušenj glede varnosti uporabe zdravila Dafiro HCT pri bolnikih, ki jim je bila nedavno presajena ledvica.
English: Haemodynamically unstable heart failure after acute myocardial infarction.
Slovenian: Hemodinamično nestabilno srčno popuščanje po akutnem miokardnem infarktu.
English: if you are allergic to amlodipine or to any other calcium channel blockers, valsartan, hydrochlorothiazide, sulphonamide-derived medicines (medicines used to treat chest or urinary infections), or any of the other ingredients of this medicine (listed in section 6).
Slovenian: če ste alergični na amlodipin, na kateri koli zaviralec kalcijevih kanalčkov, valsartan, hidroklorotiazid, zdravila sulfonamidne vrste (zdravila za zdravljenje okužb v prsnem košu in okužb sečil) ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: The dose of Dafiro HCT should be based on the doses of the individual components of the combination at the time of switching.
Slovenian: Odmerek zdravila Dafiro HCT mora ustrezati odmerkom posameznih učinkovin kombinacije v času prehoda.
English: Patients taking hydrochlorothiazide should be informed of the risk of NMSC and advised to regularly check their skin for any new lesions and promptly report any suspicious skin lesions.
Slovenian: Bolniki, ki se zdravijo s hidroklorotiazidom, morajo biti obveščeni o tveganju za razvoj nemelanomskega kožnega raka, in treba jim je svetovati, naj si redno pregledujejo kožo in naj takoj obvestijo zdravnika, če najdejo kakršne koli na novo nastale sumljive kožne spremembe.
English: Stopping your treatment with Dafiro HCT may cause your disease to get worse.
Slovenian: Če prenehate jemati zdravilo Dafiro HCT, se lahko vaša bolezen poslabša.
English: • skin and lip cancer (non-melanoma skin cancer)
Slovenian: • kožni rak in rak ustnice (nemelanomski kožni rak)
English: Dafiro HCT can be taken with or without food.
Slovenian: Zdravilo Dafiro HCT je mogoče jemati s hrano ali brez nje.
English: • inflamed pancreas, which may cause severe abdominal and back pain accompanied with feeling of being very unwell
Slovenian: • vnetje trebušne slinavke, ki lahko povzroči hude bolečine v trebuhu in hrbtu, ki jih spremlja zelo slabo počutje
English: Amlodipine elimination from plasma is biphasic, with a terminal elimination half-life of approximately 30 to 50 hours.
Slovenian: Izločanje amlodipina iz plazme je dvofazna s končnim razpolovnim časom izločanja približno 30 do 50 ur.
English: Due to the risk of hypokalaemia, hydrochlorothiazide should be administered with caution when associated with medicinal products that could induce torsades de pointes, in particular Class Ia and Class III antiarrhythmics and some antipsychotics.
Slovenian: Zaradi nevarnosti hipokaliemije je potrebna previdnost pri uporabi hidroklorotiazida v kombinaciji z zdravili, ki lahko sprožijo torsades de pointes, zlasti z antiaritmiki skupin Ia in III in z nekaterimi antipsihotiki.
English: Concomitant administration of thiazide diuretics with substances that also have a blood pressure lowering effect (e.g. by reducing sympathetic central nervous system activity or direct vasodilatation) may potentiate orthostatic hypotension.
Slovenian: Sočasna uporaba tiazidnih diuretikov in snovi, ki prav tako znižujejo krvni tlak (na primer z zmanjševanjem aktivnosti simpatičnega centralnega živčevja ali z direktno vazodilatacijo) lahko okrepi ortostatsko hipotenzijo.
English: A cumulative dose-response relationship was demonstrated with an adjusted OR 2.1 (95% CI: 1.7-2.6) increasing to OR 3.9 (3.0-4.9) for high use (~25000 mg) and OR 7.7 (5.7-10.5) for the highest cumulative dose (~100000 mg) (see also section 4.4).
Slovenian: Razmerje med kumulativnim odmerkom in odzivom so dokazali s tem, da se je prilagojeni OR z 2,1 (95-odstotni IZ: 1,7-2,6), zvišal na 3,9 (3,04,9) pri velikih odmerkih (~ 25.000 mg) in celo na 7,7 (5,7-10,5) pri največjih kumulativnih odmerkih (~ 100.000 mg) (glejte tudi poglavje 4.4).
English: • abnormal liver function test
Slovenian: • patološke vrednosti testov jetrne funkcije
English: • increased muscle tension
Slovenian: • zvečana napetost mišic
English: • depression
Slovenian: • depresija
English: If patients taking Dafiro HCT suffer from dizziness, headache, fatigue or nausea the ability to react may be impaired.
Slovenian: Če se pri bolnikih, ki jemljejo zdravilo Dafiro HCT, pojavlja omotica, glavobol, utrujenost ali navzea, je njihova zmožnost reagiranja lahko zmanjšana.