FrancophonIA/ELRC3.0 huggingface dataset:
English: Treatment resulted in worsening of normally suppressed malarial infections in these animals.
Croatian: Liječenje je u tih životinja rezultiralo pogoršanjem malarijskih infekcija koje su u normalnim okolnostima suprimirane.
English: During treatment with Imatinib Teva, tell your doctor straight away if you put on weight very quickly.
Croatian: Tijekom liječenja Imatinib Tevaom odmah obavijestite svog liječnika ako vrlo brzo dobivate na težini.
English: A complete haematological response was achieved in 95% of patients.
Croatian: Potpuni je hematološki odgovor postignut u 95%
English: For patients with reduction in Bcr-Abl transcripts of at least 3 logarithms at 12 months, the probability of remaining free from progression to accelerated phase/blast crisis was 99% at 84 months.
Croatian: Za bolesnike sa smanjenjem Bcr-Abl transkripcija za najmanje 3 logaritma nakon 12 mjeseci, vjerojatnost zadržavanja stanja bez progresije u ubrzanu fazu/blastičnu krizu bila je 99% nakon 84 mjeseca.
English: Importantly, 27.7% of patients also achieved a major cytogenetic response, which was complete in 20.4% (confirmed 16%) of patients.
Croatian: Važno je napomenuti da je 27,7% bolesnika također postiglo veliki citogenetski odgovor, koji je bio potpun u 20,4% (potvrđeno 16%) bolesnika.
English: The degree of cytogenetic response and molecular response had a clear effect on long-term outcomes in patients on imatinib.
Croatian: Stupanj citogenetskog odgovora i molekularnog odgovora imao je jasan učinak na dugotrajne ishode u bolesnika na imatinibu.
English: 5 patients responded, 3 completely and 2 partially.
Croatian: 5 bolesnika je imalo odgovor, 3 kompletni i 2 parcijalni.
English: Ki values in human liver microsomes were 27, 7.5 and 7.9 µmol/l, respectively.
Croatian: Ki vrijednosti u jetrenim mikrosomima čovjeka bile su 27, 7,5, odnosno 7,9 µmol/l.
English: • Dry mouth, dry skin or dry eye.
Croatian: • Suhoća usta, suhoća kože ili suho oko.
English: 260 patients with myeloid blast crisis were enrolled.
Croatian: U ispitivanje je uključeno 260 bolesnika s mijeloičnom blastičnom krizom.
English: When female rats were dosed 14 days prior to mating and through to gestational day 6, there was no effect on mating or on number of pregnant females.
Croatian: Kada su ženke štakora dobivale dozu tijekom 14 dana prije parenja pa sve do 6. dana gestacije, nije bilo učinka na parenje ili na broj skotnih ženki.
English: • Pain in your hips or difficulty walking.
Croatian: • Bol u kukovima ili otežano hodanje.
English: The median time to progression in the overall population of 411 patients with relapsed/refractory Ph+ ALL ranged from 2.6 to 3.1 months, and median overall survival in the 401 evaluable patients ranged from 4.9 to 9 months.
Croatian: Medijan vremena do progresije u ukupnoj populaciji od 411 bolesnika s recidivirajućom ili refraktornom Ph+ ALL kretao se od 2,6 do 3,1 mjesec, a medijan ukupnog preživljenja kod 401 evaluiranog bolesnika kretao se od 4,9 do 9 mjeseci.
English: The patients were distributed in three main categories: haematological failure (29%), cytogenetic failure (35%), or intolerance to interferon (36%).
Croatian: Bolesnici su bili raspoređeni u tri glavne kategorije: hematološki neuspjeh (29%), citogenetski neuspjeh (35%) ili nepodnošenje interferona (36%).
English: The age of the DFSP patients ranged from 23 to 75 years; DFSP was metastatic, locally recurrent following initial resective surgery and not considered amenable to further resective surgery at the time of study entry.
Croatian: DFSP-om kretala se od 23 do 75 godina; DFSP je bio metastazirajući, lokalno recidivirajući nakon inicijalnog resekcijskog kirurškog zahvata te nije smatran podobnim za dodatni resekcijski kirurški zahvat u trenutku uključivanja u studiju.
English: The yearly rates of progression of any type for imatinib also decreased over time.
Croatian: Kod imatiniba su se godišnje stope progresije bilo koje vrste također smanjivale s vremenom.
English: Your doctor will discuss with you the possible risks of taking Imatinib Teva during pregnancy.
Croatian: Liječnik će Vam objasniti moguće rizike od uzimanja Imatiniba Teva tijekom trudnoće.
English: The median duration of second-line treatment with imatinib was 64 months.
Croatian: Medijan trajanja druge linije liječenja za imatinib bio je 64 mjeseca.
English: Resume treatment with imatinib at previous dose (i.e. before severe adverse reaction).
Croatian: Nastaviti imatinib u prijašnjoj dozi (tj. prije teške nuspojave).
English: Non-neoplastic lesions not identified in earlier preclinical studies were the cardiovascular system, pancreas, endocrine organs and teeth.
Croatian: Neneoplastičke lezije koje nisu identificirane u prethodnim nekliničkim ispitivanjima javile su se u kardiovaskularnom sustavu, gušterači, endokrinim organima i zubima.
English: • Blood clots in small blood vessels (thrombotic microangiopathy).
Croatian: • Krvni ugrušci u malim krvnim žilama (trombotična mikroangiopatija).
English: Imatinib Teva may cause your body to retain water (severe fluid retention).
Croatian: Imatinib Teva može izazvati zadržavanje vode u tijelu (teška retencija tekućine).
English: All patients received imatinib and consolidation chemotherapy (see Table 4) after induction and the levels of bcr-abl transcripts were identical in the two arms at 8 weeks.
Croatian: Svi su bolesnici primili imatinib i konsolidacijsku kemoterapiju (vidjeti Tablicu 3) nakon indukcije, a razine bcr-abl prijepisa bile su identične u oba kraka nakon 8 tjedana.
English: The median duration of therapy in study B2225 was 6.2 months, with a maximum duration of 24.3 months.
Croatian: Medijan trajanja terapije u studiji B2225 iznosio je 6,2 mjeseca, s maksimalnim trajanjem od
English: Since studies in animals have shown reproductive toxicity, and the potential risk for the human foetus is unknown, women of child-bearing potential who open capsules should be advised to handle the contents with caution and avoid skin-eye contact or inhalation (see section 4.6).
Croatian: Budući da su ispitivanja kod životinja pokazala reproduktivnu toksičnost, a potencijalni rizik za ljudski plod nije poznat, žene u reproduktivnoj dobi koje otvaraju kapsule treba savjetovati da pažljivo rukuju sa sadržajem te da izbjegavaju kontakt s kožom i očima ili inhaliranje (vidjeti dio 4.6).
English: Traces of the dissolved tablets may be left behind in the glass.
Croatian: Ostatke otopljenih tableta možete ostaviti u čaši.
English: The active substance imatinib demonstrates an environmental risk for sediment organisms.
Croatian: Djelatna tvar imatinib predstavlja ekološki rizik za sedimentne organizme.
English: Immune system disorders Not known
Croatian: Poremećaji imunološkog sustava Nepoznato:
English: The high rate of CHR is accompanied by the development of a complete cytogenetic response (CCyR) of 65% which is comparable to the results observed in adults.
Croatian: Visoka stopa CHR-a je praćena razvojem kompletnog citogenetskog odgovora (CCyR) od 65% što je usporedivo s rezultatima dobivenim u odraslih.
English: Chronic phase, Interferon failure 532 adult patients were treated at a starting dose of 400 mg.
Croatian: Kronična faza, neuspjeh interferona 532 odrasla bolesnika liječena su s početnom dozom od 400 mg.
English: In the F1 offspring, at the same dose level, mean body weights were reduced from birth until terminal sacrifice and the number of litters achieving criterion for preputial separation was slightly decreased.
Croatian: Pri istoj dozi u F1 potomaka, smanjile su se srednje tjelesne težine od poroda sve do konačnog žrtvovanja, a broj okota koji su postigli kriterij za prepucijsku separaciju bio je malo smanjen.
English: The results observed in a population of 211 newly diagnosed Ph+ ALL patients in four uncontrolled clinical studies (AAU02, ADE04, AJP01 and AUS01) are consistent with the results described above.
Croatian: Rezultati uočeni u populaciji od 211 novodijagnosticiranih bolesnika s Ph+ ALL-om u četiri nekontrolirana klinička ispitivanja (AAU02, ADE04, AJP01 i AUS01) su u skladu s gore opisanim rezultatima.
English: Patients had received a median of 14 months of prior IFN therapy at doses ≥ 25 x 106 IU/week and were all in late chronic phase, with a median time from diagnosis of 32 months.
Croatian: Bolesnici su prethodno primali IFN terapiju u medijanu trajanja od 14 mjeseci u dozama ≥25 x 106 IU/tjedan i svi su bili u završnoj kroničnoj fazi, sa medijanom vremena od postavljanja dijagnoze od 32 mjeseca.
English: As expected on the basis of the study design, no difference was observed in remission duration, disease-free survival or overall survival, although patients with complete molecular response and remaining in minimal residual disease had a better outcome in terms of both remission duration (p=0.01) and disease-free survival (p=0.02).
Croatian: Kao što se očekivalo na temelju dizajna studije, nije uočena razlika u trajanju remisije, preživljenju bez znakova ili ukupnom preživljenju, premda su bolesnici s kompletnim molekularnim odgovorom i s minimalnom rezidualnom bolešću imali bolji ishod u smislu dužine remisije (p=0,01) i preživljenja bez znakova bolesti (p=0,02).
English: Some medicines can interfere with the effect of Imatinib Teva when taken together.
Croatian: Neki lijekovi mogu utjecati na djelovanje Imatiniba Teva kada se uzimaju zajedno.
English: Dose increase from 100 mg to 400 mg may be considered in the absence of adverse drug reactions if assessments demonstrate an insufficient response to therapy.
Croatian: Povećanje doze od 100 mg do 400 mg može se razmotriti u odsustvu nuspojava, ako se pregledom utvrdi neadekvatan odgovor na terapiju.
English: • Sudden swelling and redness of the skin (signs of a skin infection called cellulitis).
Croatian: • Iznenadno oticanje i crvenilo kože (znakovi kožne infekcije zvane celulitis).
English: Study 0102 38-month data Myeloid blast crisis (n=260)
Croatian: 38-mjesečni podaci Mijeloična blastična kriza (n=260)
English: Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i blisteru nakon iza oznake EXP.
English: In this study, 31% of patients achieved a haematological response (36% in previously untreated patients and 22% in previously treated patients).
Croatian: U tom je ispitivanju 31% bolesnika postiglo hematološki odgovor (36% u skupini prethodno neliječenih bolesnika i 22% u skupini prethodno liječenih bolesnika).
English: • Unusual hair loss or thinning.
Croatian: • Neuobičajen gubitak ili prorijeđenost kose.
English: Due to the observational nature of this registry, haematologic, cytogenetic and molecular assessment data were available for 22, 9 and 17 of the 23 enrolled patients, respectively.
Croatian: Zbog opservacijske prirode ovog registra, podaci hematološke, citogenetske i molekularne procjene bili su dostupni za 22, 9 odnosno 17 od
English: Disease-free survival (DFS) and overall survival (OS) constantly exceeded 1 year and were superior to historical control (DFS p<0.001; OS p<0.0001) in two studies (AJP01 and AUS01).
Croatian: Preživljenje bez znakova (DFS) i ukupno preživljenje (OS) stalno premašuju 1 godinu te su superiorni nad prethodnim kontrolama (DFS p<0,001; OS p<0,0001) u dva ispitivanja (AJP01 i AUS01).
English: In clinical trials, there was an increased incidence of these events in the elderly and those with a prior history of cardiac disease.
Croatian: U kliničkim je ispitivanjima zabilježena povećana incidencija tih događaja u starijih osoba te u onih s anamnezom srčanih bolesti.
English: Mogilska 80, 31-546 Krakow Poland
Croatian: Mogilska 80, 31-546 Krakow Poljska
English: Alternating chemotherapy course: high dose chemotherapy with MTX 1 g/m2 i.v.
Croatian: Izmjenični tijek kemoterapije: visoka doza kemoterapije s MTX 1 g/m2
English: If anti-ADAMTS13-antibody is elevated in conjunction with low ADAMTS13 activity, treatment with Imatinib Teva should not be resumed.
Croatian: Ako su anti-ADAMTS13-protutijela povišena istodobno sa sniženom ADAMTS13 aktivnosti, liječenje Imatinibom Teva ne smije se nastaviti.
English: In all clinical studies 38-40% of patients were ≥ 60 years of age and 10-12% of patients were ≥ 70 years of age.
Croatian: U svim kliničkim ispitivanjima 38-40 % bolesnika bilo je u dobi ≥60 godina, a 10-12% bolesnika bilo je u dobi ≥70 godina.
English: Haematological and cytogenetic responses have been sustained for a median of 49 months (range 19-60) and 47 months (range 16-59), respectively.
Croatian: Hematološki i citogenetski odgovori su se održali za medijan od 49 mjeseci (raspon 19-60), odnosno 47 mjeseci (raspon 16-59).
English: They may increase or decrease the effect of Imatinib Teva, either leading to increased side effects or making Imatinib Teva less effective.
Croatian: Oni mogu povećati ili smanjiti učinak Imatiniba Teva bilo povećanjem nuspojava ili smanjenjem učinka Imatiniba Teva.
English: All 65 FIP1L1-PDGFRα fusion kinase positive patients achieved a CHR sustained for months (range from 1+ to 44+ months censored at the time of the reporting).
Croatian: Svih 65 bolesnika s pozitivnom FIP1L1-PDGFRα fuzijskom kinazom postiglo je CHR koji se održao mjesecima (raspon od 1+ do 44+ mjeseci, izostavljeno u trenutku izvještavanja).
English: Based on population pharmacokinetic analysis in CML patients, there was a small effect of age on the volume of distribution (12% increase in patients > 65 years old).
Croatian: Na temelju analize farmakokinetike populacije bolesnika s KML-om, učinak dobi na volumen raspodjele bio je malen (povećanje od 12% u bolesnika starih >65 godina).
English: The length of the capsule is from 23.0 mm to 23.6 mm and the width is 8.53 mm.
Croatian: Duljina kapsule je od 23,0 mm do 23,6 mm, a širina iznosi 8,53 mm.
English: Neoplasm benign, malignant and unspecified (including cysts and polyps) Rare
Croatian: Dobroćudne, zloćudne i nespecificirane novotvorine (uključujući ciste i polipe)
English: - If you are being treated for MDS/MPD:
Croatian: Ako se liječite zbog MDS/MPD-a:
English: Severe elevation of transaminases (<5%) or bilirubin (<1%) was seen in CML patients and was usually managed with dose reduction or interruption (the median duration of these episodes was approximately one week).
Croatian: Veliko povišenje vrijednosti transaminaza (<5%) ili bilirubina (<1%) uočeno je u bolesnika s KML-om i obično je liječeno smanjenjem doze ili prekidom terapije (medijan trajanja tih epizoda bio je približno tjedan dana).
English: Myeloid blast crisis
Croatian: Mijeloična blastična kriza
English: One of these intermediates was also positive in the mouse lymphoma assay.
Croatian: Jedan od tih međuproizvoda je također bio pozitivan na uzorku mišjeg limfoma.
English: Two intermediates of the manufacturing process, which are also present in the final product, are positive for mutagenesis in the Ames assay.
Croatian: Dva međuproizvoda, koji su također prisutni u gotovom proizvodu, su u Amesovom testu pozitivna na mutagenezu.
English: Progression was defined as any of the following events: progression to accelerated phase or blast crisis, death, loss of CHR or MCyR, or in patients not achieving a CHR an increasing WBC despite appropriate therapeutic management.
Croatian: Progresija je definirana kao bilo koji od sljedećih događaja: progresija u ubrzanu fazu ili blastičnu krizu, smrt, gubitak CHR-a ili MCyR-a, ili u bolesnika koji ne postižu CHR povećanje broja leukocita unatoč odgovarajućem terapijskom liječenju.
English: The decreases in white blood cell (WBC) and neutrophil counts occurred mainly during the first six weeks of therapy, with values remaining relatively stable thereafter.
Croatian: Do smanjenja broja leukocita (Lkc) i broja neutrofila uglavnom je došlo tijekom prvih šest tjedana terapije, a vrijednosti su nakon toga ostale relativno stabilne.
English: - Patients who are concerned about their fertility while taking Imatinib Teva are advised to consult with their doctor.
Croatian: - Bolesnicima koji su zabrinuti za svoju plodnost tijekom uzimanja Imatiniba Teva se preporučuje da se posavjetuju sa svojim liječnikom.
English: However, since the effects of low-dose exposure of the infant to imatinib are unknown, women taking imatinib should not breastfeed.
Croatian: Međutim, budući da učinci izloženosti niskim dozama imatiniba u dojenčadi nisu poznati, žene koje uzimaju imatinib ne smiju dojiti.
English: The primary efficacy endpoint of the study is progression-free survival.
Croatian: Primarni ishod ispitivanja djelotvornosti bio je preživljenje bez progresije.
English: This will help protect you from stomach problems when taking Imatinib Teva.
Croatian: To će Vam pomoći u zaštiti od želučanih problema prilikom uzimanja Imatiniba Teva.
English: Total bilirubin: = 1.5 ULN AST: >ULN (can be normal or < ULN if total bilirubin is > ULN)
Croatian: Ukupni bilirubin: = 1,5 GGN AST: >GGN (može biti normalan ili <GGN ako je ukupni bilirubin >GGN)
English: • Adult and paediatric patients with Ph+ CML in chronic phase after failure of interferon-alpha therapy, or in accelerated phase or blast crisis.
Croatian: • Odraslih i pedijatrijskih bolesnika s Ph+ KML-om u kroničnoj fazi nakon neuspjeha terapije interferonom-alfa, ili u ubrzanoj fazi ili u blastičnoj krizi.
English: If laboratory or clinical findings associated with TMA occur in a patient receiving Imatinib Teva , treatment should be discontinued and thorough evaluation for TMA, including ADAMTS13 activity and antiADAMTS13-antibody determination, should be completed.
Croatian: Ako se laboratorijski ili klinički nalaz povezan s TMA-om javi u bolesnika koji prima Imatinib Teva, liječenje je potrebno prekinuti i provesti temeljito istraživanje TMA, uključujući ADAMTS13 aktivnost i određivanje anti-ADAMTS13-protutijela.
English: Other adverse reactions were reported with lower or equal frequency.
Croatian: Ostale nuspojave su zabilježene s nižom ili istom učestalošću.
English: Depending on your condition the usual starting dose is either 400 mg or 600 mg:
Croatian: Ovisno o Vašem stanju, uobičajena početna doza je ili 400 mg ili 600 mg:
English: Imatinib should not be used during pregnancy unless clearly necessary.
Croatian: - Imatinib Teva se ne smije upotrebljavati tijekom trudnoće, osim ako to nije neophodno.
English: A major response combines both complete and partial responses: complete (0% Ph+ metaphases), partial (1-35%)
Croatian: Veliki odgovor je kombinacija potpunih i djelomičnih odgovora: potpuni (0% Ph+ metafaza), djelomični (1-35%)
English: The increase is approximately 1.5 to 2-fold, corresponding to a 1.5-fold elevation of plasma AGP, to which imatinib binds strongly.
Croatian: Povećanje je otprilike 1,5 do 2 puta veće, a odgovara 1,5 puta većem povećanju α-kiselog glikoproteina u plazmi, za koji se imatinib snažno veže.
English: The length of the capsule is from 19.1 mm to 19.7 mm and the width is 6.91 mm. Imatinib Teva 400 mg hard capsules
Croatian: Duljina kapsule je od 19,1 mm do 19,7 mm, a širina iznosi 6,91 mm Imatinib Teva 400 mg tvrde kapsule
English: Blast crisis is defined as blasts ≥ 30% in blood or bone marrow or extramedullary disease other than hepatosplenomegaly.
Croatian: Blastična se kriza definira kao prisutnost ≥30% blasta u krvi ili koštanoj srži ili postojanje ekstramedularne bolesti osim hepatosplenomegalije.
English: Using this approach, the estimated cumulative response rates for first-line treatment with imatinib improved from 12 months of therapy to 84 months of therapy as follows: CHR from 96.4% to 98.4% and CCyR from 69.5% to 87.2%, respectively.
Croatian: Korištenjem tog pristupa, procijenjene kumulativne stope odgovora za prvu liniju liječenja imatinibom su se poboljšale od 12 mjeseci do 84 mjeseca terapije kako slijedi: CHR od 96,4% do 98,4% i CcyR od 69,5% do 87,2%.
English: This is because Imatinib Teva could cause hepatitis B to become active again, which can be fatal in some cases.
Croatian: To je potrebno jer Imatinib Teva može uzrokovati ponovnu aktivaciju hepatitisa B, što u nekim slučajevima može rezultirati smrtnim ishodom.
English: At 84 months the estimated overall survival is 86.4% (83, 90) vs. 83.3% (80, 87) in the randomised imatinib and the IFN+Ara-C groups, respectively (p=0.073, log-rank test).
Croatian: Nakon 84 mjeseca, procijenjeno ukupno preživljenje iznosi 86,4% (83, 90) u odnosu na 83,3% (80, 87) u randomiziranim skupinama koje primaju imatinib odnosno IFN+Ara-C (p=0,073, log-rang test).
English: • Anorexia, weight loss or a disturbed sense of taste.
Croatian: • Anoreksija, smanjenje tjelesne težine ili poremećaj u osjetu okusa.
English: • Risk Management Plan (RMP) Not applicable.
Croatian: LIJEKA • Plan upravljanja rizikom (RMP)
English: In addition a further 24 patients with MDS/MPD were reported in 13 publications.
Croatian: Osim toga, verificirana su dodatna 24 bolesnika s MDS/MPB-om u 13 publikacija.
English: The effect of imatinib treatment on survival in chronic phase, newly diagnosed CML has been further examined in a retrospective analysis of the above reported imatinib data with the primary data from another Phase III study using IFN+Ara-C (n=325) in an identical regimen.
Croatian: Učinak liječenja imatinibom na preživljenje u kroničnoj fazi novodijagnosticiranog KML-a je dodatno ispitivan u retrospektivnoj analizi gore navedenih imatinib podataka uz primarne podatke iz drugog ispitivanja faze III u kojem je primjenjivan IFN+Ara-C (n=325) u identičnom režimu.
English: • Numbness of the hands or feet.
Croatian: • Utrnulost šaka ili stopala.
English: The comparison of AUC(0-24) on day 8 and day 1 at the 340 mg/m2/day dose level revealed a 1.7-fold drug accumulation after repeated once-daily dosing.
Croatian: Usporedba AUC(0-24) na dan 8 i dan 1 uz dozu od 340 mg/m2/dan otkrila je 1,7 puta veću akumulaciju lijeka nakon ponovljenog doziranja jednom na dan.
English: In GIST patients (study B2222), 6.8% of grade 3 or 4 ALT (alanine aminotransferase) elevations and 4.8% of grade 3 or 4 AST (aspartate aminotransferase) elevations were observed.
Croatian: U bolesnika s GIST-om (studija B2222), kod njih 6,8% zapaženo je povišenje ALT (alanin-aminotransferaza) 3. ili 4. stupnja, a kod 4,8% povišenje AST (aspartat-aminotransferaza) 3. ili 4. stupnja.
English: Imatinib at 400 mg twice daily had an inhibitory effect on CYP2D6-mediated metoprolol metabolism, with metoprolol Cmax and AUC being increased by approximately 23% (90%CI [1.16-1.30]).
Croatian: Imatinib 400 mg dvaput na dan imao je inhibitorni učinak na metabolizam metoprolola posredovan CYP2D6, pri čemu su se Cmax i AUC metoprolola povećali za otprilike 23% (90%CI [1,16-1,30]).
English: Cranial irradiation (Block 5 only) 12 Gy in 8 fractions for all patients that are CNS1 and CNS2 at
Croatian: Kranijalna iradijacija (Samo blok br. 5) 12 Gy u 8 frakcija za sve bolesnike koji imaju CNS1 i CNS2 u trenutku dijagnoze
English: Imatinib can also inhibit cellular events mediated by activation of these receptor kinases.
Croatian: Imatinib može također inhibirati i stanična zbivanja posredovana aktivacijom tih receptorskih kinaza.
English: • The treatment of adult patients with unresectable dermatofibrosarcoma protuberans (DFSP) and adult patients with recurrent and/or metastatic DFSP who are not eligible for surgery.
Croatian: • Liječenje odraslih bolesnika s inoperabilnim dermatofibrosarkomom protuberans (DFSP) i odraslih bolesnika s rekurentnim i/ili metastazirajućim DFSP-om koji nisu podobni za kirurški zahvat.
English: When salvage therapy with imatinib was administered in patients who did not respond or who responded poorly to chemotherapy, it resulted in 9 patients (81.8%) out of 11 achieving a complete haematological response.
Croatian: Kada je terapija imatinibom primijenjena bolesnicima koji nisu odgovorili ili su slabo odgovorili na kemoterapiju, 9 od 11 bolesnika (81,8%) postiglo je kompletni hematološki odgovor.
English: Total bilirubin: > 1.5-3.0 ULN AST: any
Croatian: Ukupni bilirubin: >1,5-3,0 GGN AST: bilo koja vrijednost
English: If this applies to you, tell your doctor without taking Imatinib Teva.
Croatian: Ako se to odnosi na Vas, obavijestite svog liječnika bez uzimanja Imatinib Teva.