FrancophonIA/ELRC3.0 huggingface dataset:
English: These factors include: - change in the injection area - improved insulin sensitivity (e.g. by removal of stress factors) - unaccustomed, increased or prolonged physical activity - intercurrent illness (e.g. vomiting, diarrhoea) - inadequate food intake - missed meals - alcohol consumption - certain uncompensated endocrine disorders, (e.g. in hypothyroidism and in anterior pituitary or adrenocortical insufficiency) - concomitant treatment with certain other medicinal products (see section 4.5).
Croatian: Ti čimbenici uključuju: - promjenu područja injiciranja - poboljšanu osjetljivost na inzulin (npr. uklanjanjem čimbenika stresa) - povećanu ili produljenu tjelesnu aktivnost na koju bolesnik nije navikao - interkurentnu bolest (npr. povraćanje, proljev) - neodgovaraući unos hrane - propuštanje obroka - konzumaciju alkohola - neke nekompenzirane endokrine poremećaje (npr. kod hipotireoze i insuficijencije adenohipofize ili kore nadbubrežne žlijezde) - istodobno liječenje određenim drugim lijekovima (vidjeti dio 4.5). - liksisenatid i/ili inzulin u kombinaciji sa sulfonilurejom mogu rezultirati povećanim rizikom od hipoglikemije.
English: * Documented symptomatic hypoglycaemia was an event during which typical symptoms of hypoglycaemia were accompanied by a measured plasma glucose concentration of ≤3.9 mmol/L.
Croatian: Događaji po bolesnik godini, n * Zabilježena simptomatska hipoglikemija bio je događaj tijekom kojeg su tipični simptomi hipoglikemije bili praćeni s izmjerenim koncentracijama glukoze u plazmi ≤3,9 mmol/l.
English: Always use another Suliqua (30- 60) pen to complete your dose and no other pen.
Croatian: Uvijek upotrijebite drugu Suliqua (30-60) brizgalicu da upotpunite svoju dozu, a ne neku drugu brizgalicu.
English: In the event of blocked needles patients must follow the instructions described in the “Instructions for Use” accompanying the package leaflet.
Croatian: U slučaju začepljenja igle, bolesnici se moraju pridržavati uputa opisanih u 'Uputama za uporabu' koje dolaze zajedno s uputom o lijeku.
English: The patient should discard the needle after each injection.
Croatian: Nakon svake injekcije bolesnik treba baciti iglu.
English: Insulin glargine (100 units/ml)** ≥20 to <30 units
Croatian: Inzulin glargin (100 jedinica/ml)** ≥20 do <30 jedinica
English: Neither status for anti-insulin glargine antibodies nor for anti-lixisenatide antibodies had a clinically relevant impact on safety or efficacy.
Croatian: Status protutijela na inzulin glargin, kao ni status protutijela na liksisenatid, nisu imali klinički značajan učinak na sigurnost i djelotvornost.
English: Suliqua is available in two pens, providing different dosing options, i.e. Suliqua (10-40) pen, Suliqua (30-60) pen respectively.
Croatian: Suliqua je dostupna u dvije brizgalice koje omogućuju različito doziranje, tj. Suliqua (10-40) brizgalica i Suliqua (30-60) brizgalica.
English: The pharmacokinetic and pharmacodynamic findings indicate that the effect of the subcutaneous injection with insulin glargine is principally based on exposure to M1.
Croatian: Glavni cirkulirajući metabolit u plazmi je M1. Farmakokinetički i farmakodinamički nalazi pokazuju da se učinak supkutane injekcije inzulina glargina uglavnom temelji na izloženosti metabolitu M1.
English: • Ensure that you use the right medicine.
Croatian: • uvjerite se da koristite odgovarajući lijek.
English: After subcutaneous administration of insulin glargine/lixisenatide combinations to patients with type 1 diabetes, the median tmax of lixisenatide was in the range of 2.5 to 3.0 hours.
Croatian: Nakon supkutane primjene kombinacije inzulina glargina i liksisenatida bolesnicima sa šećernom bolešću tipa 1, medijan tmax liksisenatida je bio u rasponu 2,5-3,0 sata.
English: • When to check your blood sugar level and if you need to carry out urine tests.
Croatian: • Vam reći kada trebate provjeravati razinu šećera u krvi i trebate li napraviti pretrage mokraće
English: What Suliqua looks like and contents of the pack Suliqua is a clear and colourless solution for injection (injection) filled in a glass cartridge inserted in a SoloStar pre-filled pen.
Croatian: Suliqua je bistra i bezbojna otopina za injekciju (injekcija) u staklenom ulošku koji je umetnut u SoloStar napunjenu brizgalicu.
English: Reasons why hyperglycaemia may happen:
Croatian: Razlozi zbog kojih dolazi do hiperglikemije:
English: Animal studies with lixisenatide or insulin glargine do not indicate direct harmful effects with respect to fertility.
Croatian: Ispitivanja liksisenatida ili inzulina glargina na životinjama ne ukazuju na izravne štetne učinke na plodnost.
English: • If there are not enough dose steps left in your pen for your dose, the dose selector will stop at the number of dose steps left.
Croatian: Ako u Vašoj brizgalici nije ostalo dovoljno odmjernih koraka, izbornik doze će se zaustaviti na broju preostalih odmjernih koraka.
English: This medicinal product contains less than 1 mmol (23 mg) sodium per dose, i.e. it is essentially 'sodium-free'.
Croatian: Ovaj lijek sadrži manje od 1 mmol (23 mg) natrija po dozi, tj.zanemarive količine natrija.
English: 6.6 Special precautions for disposal and other handling Before first use, the pen must be taken out of the refrigerator and stored below 25°C for 1 to 2 hours.
Croatian: Prije prve uporabe, brizgalica se mora izvaditi iz hladnjaka i čuvati na temperaturi ispod 25°C 1 do 2 sata.
English: • you have severe kidney disease or you are on dialysis as the use of this medicine will not be recommended.
Croatian: • imate tešku bolest bubrega ili ste na dijalizi, jer se u tom slučaju ne preporučuje primjena ovoga lijeka.
English: This pen is olive coloured with a brown injection button.
Croatian: Ova brizgalica je maslinaste boje sa smeđim dugmetom za injiciranje.
English: Patients must be instructed to always check the pen label before each injection to avoid accidental mix-ups between the two different strengths of Suliqua and mix-ups with other injectable diabetes medicinal products.
Croatian: Bolesnike se mora uputiti da uvijek provjere naljepnicu na brizgalici prije svakog injiciranja kako bi se izbjegle slučajne zamjene između dviju jačina lijeka Suliqua i zamjene s drugim lijekovima za šećernu bolest koji se injiciraju.
English: If you have injected too much of this medicine, your blood sugar level may become too low (hypoglycaemia).
Croatian: Ako ste injicirali previše ovog lijeka, razina šećera u krvi može postati preniska (hipoglikemija).
English: The impact of the combination of insulin glargine and lixisenatide on the pharmacodynamics of lixisenatide has not been studied in phase 1 studies.
Croatian: Učinak kombinacije inzulina glargina i liksisenatida na farmakodinamiku liksisenatida nije ispitivan u ispitivanjima faze 1.
English: Switch from GLP-1 receptor agonist has not been studied.
Croatian: Prijelaz s liječenja agonistima GLP-1 receptora nije ispitivan.
English: • Inject it into the front of your thighs, upper arms or the front of your waist (abdomen).
Croatian: • Injicirate ga u prednji dio bedra, nadlakticu ili prednji dio struka (trbuha).
English: Substances that may reduce the blood-glucose-lowering effect include corticosteroids, danazol, diazoxide, diuretics, glucagon, isoniazid, oestrogens and progestogens, phenothiazine derivatives, somatropin, sympathomimetic medicinal products (e.g. epinephrine [adrenaline], salbutamol, terbutaline), thyroid hormones, atypical antipsychotic medicinal products (e.g. clozapine and olanzapine) and protease inhibitors.
Croatian: Tvari koje mogu smanjiti učinak snižavanja razine glukoze u krvi uključuju kortikosteroide, danazol, diazoksid, diuretike, glukagon, izoniazid, estrogene i progestagene, derivate fenotiazina, somatropin, simpatomimetičke lijekove (npr. epinefrin [adrenalin], salbutamol, terbutalin), hormone štitnjače, atipične antipsihotike (npr. klozapin i olanzapin) te inhibitore proteaze.
English: Suliqua should not be used during pregnancy.
Croatian: Suliqua se ne smije primjenjivati u trudnoći.
English: End of study (mean)
Croatian: Kraj ispitivanja (srednja vrijednost)
English: At the end of the run-in period, patients with an HbA1c between 7 and 10% , FPG ≤7.77 mmol/L and insulin glargine daily dose of 20 to 50 units, were randomised to either Suliqua (n=367) or insulin glargine (n=369).
Croatian: Na kraju uvodnog razdoblja, bolesnici s vrijednostima HbA1c između 7% i 10%, glukozom u plazmi natašte ≤7,77 mmol/l i dnevnom dozom inzulina glargina od 20 do 50 jedinica, randomizirani su na lijek Suliqua (n = 367) ili na inzulin glargin (n = 369).
English: Effect of age, race, and gender on the pharmacokinetics of insulin glargine has not been evaluated.
Croatian: Utjecaj dobi, rase i spola na farmakokinetiku inzulina glargina nije procijenjen.
English: Warnings and precautions Talk to your doctor, pharmacist or nurse before using Suliqua if:
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego primijenite lijek Suliqua ako:
English: Hyperglycaemia (high blood sugar levels)
Croatian: Hiperglikemija (visoka razina šećera u krvi)
English: • Keep new pens in the refrigerator between 2°C to 8°C.
Croatian: Čuvajte nove brizgalice u hladnjaku na temperaturi između 2°C i 8°C.
English: Always use a new needle.
Croatian: Uvijek upotrijebite novu iglu.
English: The combination of medicinal products in this pen is for the daily injection of 10 to 40 dose steps of Suliqua.
Croatian: Kombinacija lijekova u ovoj brizgalici namijenjena je za dnevno injiciranje 10-40 odmjernih koraka lijeka Suliqua.
English: After screening, eligible patients (n=1018) entered a 6 week run-in phase where patients remained on or switched to insulin glargine, in case they took another basal insulin, and had their insulin dose titrated/stabilised while continuing metformin (if previously taken).
Croatian: Nakon probira, bolesnici koji su zadovoljavali uvjete (n = 1018) ušli su 6-tjedno uvodno razdoblje, u kojem su bolesnici ostali na inzulinu glarginu ili su se prebacili na inzulin glargin, u slučaju da su prethodno primali drugi bazalni inzulin, i njihova je doza inzulina titrirana/stabilizirana, dok su tjedni
English: Patients in the Suliqua group reported a statistically significantly greater decrease in the average 7-point self-monitored plasma glucose (SMPG) profile from baseline to Week 30 (-3.35 mmol/L) compared to patients in the insulin glargine group (-2.66 mmol/L; difference -0.69 mmol/L) and patients in the lixisenatide group (-1.95 mmol/L; difference -1.40 mmol/L) (p<0.0001 for both comparisons).
Croatian: Bolesnici koji su bili u skupini s lijekom Suliqua, prijavili su statistički značajno veće smanjenje u prosječnom profilu razine glukoze u sedam točaka dobivenih samomjerenjem (engl. 7-point selfmonitored plasma glucose (SMPG)) od početka do 30. tjedna (-3,35 mmol/l) u usporedbi s bolesnicima u skupini s inzulinom glarginom (-2,66 mmol/l; razlika -0,69 mmol/l) i s bolesnicima u skupini s liksisenatidom (-1,95 mmol/l; razlika -1,40 mmol/l) (p<0,0001 za obje usporedbe).
English: Warning signs of hyperglycaemia
Croatian: Upozoravajući znakovi hiperglikemije
English: In the switch from basal insulin clinical study the starting dose was 20 dose steps (20 units insulin glargine and 10 mcg lixisenatide) or 30 dose steps, (30 units insulin glargine and 10 mcg lixisenatide), see section 4.2, depending on the previous insulin dose.
Croatian: U kliničkom ispitivanju gdje je došlo do prijelaza s bazalnog inzulina, početna je doza bila 20 odmjernih koraka (20 jedinica inzulina glargina i 10 µg liksisenatida) ili 30 odmjernih koraka (30 jedinica inzulina glargina i 10 µg liksisenatida), vidjeti dio 4.2, ovisno o prethodnoj dozi inzulina.
English: • Throw away the used needle in a sharps container, or as told by your pharmacist or local authority.
Croatian: • Bacite iskorištene igle u neprobojan spremnik ili ih zbrinite sukladno uputama ljekarnika ili lokalnog nadležnog tijela.
English: Starting dose and pen
Croatian: Početna doza i brizgalica
English: Type I colourless glass cartridge with a black plunger (bromobutyl rubber) and a flanged cap (aluminium) with inserted laminated sealing disks (bromobutyl rubber on the medicinal product side and polyisoprene on the outside) containing 3 ml of solution.
Croatian: I s crnim klipom (brombutilna guma) te prstenastim zatvaračem (aluminij) i umetnutim laminiranim zaštitnim pločicama (brombutilna guma sa strane okrenute prema lijeku i poliizopren s vanjske strane) koji sadrži 3 ml otopine.
English: Your blood sugar level may either rise or fall if you take:
Croatian: Razina šećera u krvi može porasti ili pasti ako uzmete:
English: The median duration of study follow-up was 6.2 years.
Croatian: Medijan trajanja praćenja ispitvanja bio je tjedni
English: The mean BMI at baseline was 31.1 kg/m2 with 57.3% of patients having a BMI ≥30 kg/m2.
Croatian: Srednja vrijednost ITM na početku bila je 31,1 kg/m2, s 57,3% bolesnika s vrijednošću ITM≥30 kg/m2.
English: After concomitant administration of warfarin 25 mg with repeated dosing of lixisenatide 20 mcg, there were no effects on AUC or INR (International Normalised Ratio) while Cmax was reduced by 19% and tmax was delayed by 7 hours.
Croatian: Nakon istodobne primjene varfarina u dozi od 25 mg i ponovljenih doza liksisenatida od 20 µg nije bilo učinaka na AUC ni INR (međunarodni normalizirani omjer), dok se Cmax smanjio za 19%, a tmax odgodio za 7 sati.
English: A new needle must always be attached before each use.
Croatian: Prije svake uporabe mora se pričvrstiti nova igla.
English: If you have missed a dose of Suliqua or if you have not injected enough insulin, your blood sugar level may become too high (hyperglycaemia):
Croatian: Ako ste propustili dozu lijeka Suliqua ili niste injicirali dovoljno inzulina, razina šećera u krvi može postati previsoka (hiperglikemija).
English: Hypoglycaemia is also more likely to happen if:
Croatian: Hipoglikemija se također češće može pojaviti:
English: The combination of medicinal products in this pen is for the daily injection of 30 to 60 dose steps Suliqua.
Croatian: Kombinacija lijekova u ovoj brizgalici namijenjena je za dnevno injiciranje 30-60 odmjernih koraka lijeka Suliqua.
English: 10 dose steps (10 units/5 mcg)*
Croatian: 10 odmjernih koraka (10 jedinica/5 µg)*
English: In patients with mild to moderate renal impairment using Suliqua, frequent glucose monitoring and dose adjustment may be necessary.
Croatian: U bolesnika s blagim do umjerenim oštećenjem funkcije bubrega koji koriste lijek Suliqua, mogu biti potrebni redovito praćenje glukoze i prilagodba doze.
English: • you have type 1 diabetes, as Suliqua is used for type 2 diabetes and this medicine will not be right for you.
Croatian: • imate šećernu bolesti tipa 1 s obzirom da se lijek Suliqua primjenjuje kod šećerne bolesti tipa 2 i ovaj lijek neće biti prikladan za Vas.
English: Sustained carbohydrate intake and observation may be necessary because hypoglycaemia may recur after apparent clinical recovery.
Croatian: Možda će biti potrebno održavati unos ugljikohidrata i nadzirati bolesnika jer se nakon prividnog kliničkog poboljšanja hipoglikemija može ponovo javiti.
English: [-1.9 to -0.9]
Croatian: [-1,9 do -0,9]
English: If you forget to use Suliqua
Croatian: Ako ste zaboravili primijeniti lijek Suliqua
English: Administration of the oral contraceptive 1 hour or 4 hours after lixisenatide did not affect AUC and t1/2 of ethinylestradiol and levonorgestrel, whereas Cmax of ethinylestradiol was decreased by 52% and 39%, respectively and Cmax of levonorgestrel was decreased by 46% and 20%, respectively and median tmax was delayed by 1 to 3 hours.
Croatian: Primjena oralnog kontraceptiva 1 sat odnosno 4 sata nakon liksisenatida nije utjecala na AUC ni t1/2 etinilestradiola i levonorgestrela, ali je smanjila Cmax etinilestradiola za 52% odnosno 39% te Cmax levonorgestrela za 46% odnosno 20%, dok je medijan tmax bio odgođen za 1 do 3 sata.
English: No interaction studies with Suliqua have been performed.
Croatian: Nisu provedena ispitivanja interakcija za lijek Suliqua.
English: Hypoglycaemia (low blood sugar levels)
Croatian: Hipoglikemija (niska razina šećera u krvi)
English: - Never use a syringe to remove medicine from your pen.
Croatian: -Nikada nemojte koristiti štrcaljku kako biste izvukli lijek iz svoje brizgalice.
English: • Talk with your healthcare provider about how to inject, before using your pen.
Croatian: • Prije korištenja svoje brizgalice, razgovarajte sa zdravstvenim radnikom o tome kako injicirati lijek.
English: 20 dose steps (20 units/10 mcg)*
Croatian: 20 odmjernih koraka (20 jedinica/10 µg)*
English: • This pen provides a dose of 30 to 60 dose steps in one injection, in steps of 1 dose step.
Croatian: • Ovom brizgalicom može se primijeniti doza od 30 do 60 odmjernih koraka u jednoj injekciji, u koracima od jednog odmjernog koraka.
English: Do not return the pen to a refrigerator and do not freeze.
Croatian: Nemojte vraćati brizgalicu u hladnjak i nemojte je zamrzavati.
English: sanofi-aventis groupe 54, rue La Boétie 75008 Paris France
Croatian: sanofi-aventis groupe 54, rue La Boétie F - 75008 Paris Francuska
English: Insulin glargine (100 units/ml)** ≥30 to ≤60 units
Croatian: Inzulin glargin (100 jedinica/ml)** ≥30 do ≤60 jedinica
English: [-1.8 to -0.9]
Croatian: [-1,8 do -0,9]
English: If your blood sugar falls too low, you may pass out (become unconscious).
Croatian: Ako Vam se razina šećera u krvi previše snizi, možete se onesvijestiti (izgubiti svijest).
English: • Too high blood sugar (hyperglycaemia).
Croatian: • previsok šećer u krvi (hiperglikemija).
English: Thirst, increased need to urinate, tiredness, dry skin, reddening of the face, loss of appetite, low blood pressure, fast heartbeat, and urine test showing glucose and ketone bodies.
Croatian: Žeđ, povećana potreba za mokrenjem, umor, suha koža, crvenilo lica, gubitak teka, nizak krvni tlak, ubrzani otkucaji srca, pojava glukoze i ketonskih tijela u mokraći.
English: Patients with type 2 diabetes, treated with metformin alone or metformin and a second OAD treatment that could be a sulfonylurea or a glinide or a sodium-glucose co-transporter-2 (SGLT-2) inhibitor or a dipeptidyl peptidase-4 (DPP-4) inhibitor, and who were not adequately controlled with this treatment (HbA1c range 7.5% to 10% for patients previously treated with metformin alone and 7.0% to 9% for patients previously treated with metformin and a second oral anti-diabetic treatment) entered a run-in period for 4 weeks.
Croatian: Bolesnici sa šećernom bolešću tipa 2, liječeni samo metforminom ili metforminom i drugim oralnim antidijabetikom koji je mogao biti sulfonilureja, glinid, inhibitor kotransportera natrija i glukoze-2 (SGLT-2, engl. sodium-glucose co-transporter-2) ili inhibitor dipeptidil peptidaze-4 (DPP-4), te koji nisu bili odgovarajuće kontrolirani ovakvim liječenjem (raspon HbA1c bio je od 7,5% do 10% za bolesnike prethodno liječene samo metforminom i 7,0% do 9% za bolesnike prethodno liječene metforminom i drugim oralnim antidijabetikom) uključeni su u 4-tjedno uvodno razdoblje.
English: Use only clear, colourless solution.
Croatian: Primijeniti samo bistru, bezbojnu otopinu.
English: No dose adjustment of lixisenatide is needed in patients with hepatic impairment (see section 5.2).
Croatian: Nije potrebna prilagodba doze liksisenatida u bolesnika s oštećenjem funkcije jetre (vidjeti dio 5.2).
English: • If you think your pen is damaged, do not use it. Get a new one.
Croatian: • Ako mislite da bi Vaša brizgalica mogla biti oštećena, nemojte je upotrijebiti.
English: If a dose lower than 30 dose steps is needed, use the Suliqua 100units/ml + 50 micrograms pre-filled pen (Suliqua (10-40) pen.
Croatian: Ako Vam je potrebna manja doza od 30 odmjernih koraka, koristite Suliqua 100 jedinica/ml + 50 mikrograma/ml napunjenu brizgalicu (Suliqua (10-40) brizgalica).
English: Based on these results, no dose adjustment for digoxin is required when co-administered with lixisenatide.
Croatian: Na temelju ovih rezultata nije potrebna nikakva prilagodba doze digoksina kad se primjenjuje istodobno s liksisenatidom.
English: After subcutaneous administration of insulin glargine/lixisenatide combinations to patients with type 1 diabetes, insulin glargine showed no pronounced peak.
Croatian: Nakon supkutane primjene kombinacije inzulina glargina i liksisenatida bolesnicima sa šećernom bolešću tipa 1, inzulin glargin nije pokazao izraženu vršnu koncentraciju.
English: The maximum daily dose is 60 units insulin glargine and 20 mcg lixisenatide corresponding to 60 dose steps.
Croatian: Maksimalna dnevna doza je 60 jedinica inzulina glargina i 20 µg liksisenatida, što odgovara dozi od 60 odmjernih koraka.
English: Body weight has no clinically relevant effect on lixisenatide AUC.
Croatian: Tjelesna težina nema klinički značajan učinak na AUC liksisenatida.
English: • If you still find it hard to press in, get a new pen.
Croatian: Ako Vam je i dalje teško pritisnuti dugme za injiciranje do kraja, nabavite novu brizgalicu.
English: Grip and squeeze the widest part of the outer needle cap.
Croatian: Uhvatite i stisnite najširi dio vanjskog zatvarača igle.
English: After concomitant administration of lixisenatide 20 mcg and ramipril 5 mg during 6 days, the AUC of ramipril was increased by 21% while the Cmax was decreased by 63%.
Croatian: Nakon istodobne primjene liksisenatida u dozi od 20 µg i ramiprila u dozi od 5 mg tijekom 6 dana, AUC ramiprila povećao se za 21%, dok se Cmax smanjio za 63%.
English: • Disopyramide, for some heart problems.
Croatian: • dizopiramid, za liječenje nekih srčanih tegoba
English: In the Add-on to metformin clinical study the treatment was started at 10 dose steps (10 units insulin glargine and 5 mcg lixisenatide).
Croatian: U kliničkom ispitivanju lijeka koji se koristio kao dodatak metforminu, liječenje je započelo s 10 odmjernih koraka (10 jedinica inzulina glargina i 5 µg liksisenatida).
English: Oral anti-diabetic treatment (insulin naïve patients)
Croatian: Liječenje oralnim antidijabeticima (bolesnici koji prethodno nisu primjenjivali inzulin)
English: • This pen provides a dose of 10 to 40 dose steps in one injection, in steps of 1 dose step.
Croatian: • Ovom brizgalicom može se primijeniti doza od 10 do 40 odmjernih koraka u jednoj injekciji, u koracima od jednog odmjernog koraka.
English: • Corticosteroids such as cortisone and prednisolone, for inflammation.
Croatian: • kortikosteroide poput kortizona ili prednizolona -za liječenje upale
English: Store pen away from direct heat or direct light.
Croatian: Čuvati brizgalicu dalje od izravnog izvora topline ili svjetlosti.
English: See table and figure below for the other endpoints in the study.
Croatian: Vidjeti tablicu i brojke navedene u nastavku za druge mjere ishoda u ovom ispitivanju.
English: Gastrointestinal adverse reactions were mostly mild and transient in nature.
Croatian: Nuspojave probavnog sustava većinom su bile blage i prolaznog karaktera.
English: NAME OF THE MEDICINAL PRODUCT
Croatian: Naziv lijeka
English: At Week 30, Suliqua provided statistically significant improvement in HbA1c (p-value <0.0001) compared to the individual components.
Croatian: U 30. tjednu, primjena lijeka Suliqua dovela je do statistički značajnog poboljšanja HbA1c (pvrijednost <0,0001) u usporedbi s pojedinim sastavnicama.
English: • Protease inhibitors, for HIV.
Croatian: • inhibitore proteaze, za liječenje HIV infekcija
English: • For Suliqua, one dose step always contains one unit of insulin, regardless of the Suliqua pre-filled pen being used (10-40 pen or 30-60 pen).
Croatian: • Jedan odmjerni korak lijeka Suliqua sadrži jednu jedinicu inzulina, neovisno o tome koja Suliqua napunjena brizgalica se koristi (10-40 brizgalica ili 30-60 brizgalica).
English: Figure: Mean HbA1c(%) at start of screening, randomization point and Each Time Point (Completers) and at Week 30 - mITT population
Croatian: Slika: Srednja vrijednost HbA1c (%) na početku probira, u vrijeme randomizacije i u svakoj vremenskoj točki (bolesnici koji su završili ispitivanje) i u 30. tjednu - mITT populacija
English: • Lithium salts, for mental health problems.
Croatian: • soli litija, za liječenje mentalnih poremećaja