FrancophonIA/ELRC3.0 huggingface dataset:
English: In women who have had their womb and ovaries removed, the amount of testosterone produced is halved.
Slovenian: Pri ženskah, ki so jim odstranili maternico in jajčnike, se raven proizvedenega testosterona zmanjša za polovico.
English: The full EPAR for Intrinsa can be found here.
Slovenian: Celotno evropsko javno poročilo o zdravilu (EPAR) za zdravilo Intrinsa je na voljo tukaj.
English: For the full list of all side effects reported with Intrinsa, see the
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Intrinsa, glejte navodilo za uporabo.
English: What is Intrinsa used for?
Slovenian: Za kaj se zdravilo Intrinsa uporablja?
English: How is Intrinsa used?
Slovenian: Kako se zdravilo Intrinsa uporablja?
English: How has Intrinsa been studied?
Slovenian: Kako je bilo zdravilo Intrinsa raziskano?
English: How does Intrinsa work?
Slovenian: Kako zdravilo Intrinsa deluje?
English: • Your female partner must also use a suitable method of contraception.
Slovenian: • Vaša partnerka mora prav tako uporabljati ustrezen način kontracepcije.
English: This is because it may harm an unborn baby.
Slovenian: Škoduje namreč lahko nerojenemu otroku.
English: Two highly effective and complementary forms of contraception are recommended.
Slovenian: Priporočljivi sta dve visoko učinkoviti in komplementarni obliki kontracepcije.
English: Post-hoc analysis.
Slovenian: Post hoc analiza.
English: It is important that you take the total recommended dose each day.
Slovenian: Pomembno je, da vsak dan vzamete celotni priporočeni odmerek.
English: See section 2 “Information on other ingredients in this medicine”.
Slovenian: Glejte poglavje 2 »Informacije o drugih sestavinah tega zdravila«.
English: You will have a blood test:
Slovenian: Preiskavo krvi boste imeli:
English: (8.3-NR)
Slovenian: (8,3-ND)
English: Pneumonitis is a serious condition that can often require hospital treatment.
Slovenian: Pnevmonitis je resno stanje, ki pogosto zahteva zdravljenje v bolnišnici.
English: However, the number of patients is too limited to make meaningful conclusions on the efficacy in this subgroup.
Slovenian: Vendar je bilo število bolnikov premajhno za dejanske zaključke o učinkovitosti v tej podskupini.
English: o bruising or bleeding for longer than usual if you hurt yourself
Slovenian: o podplutbe ali krvavitve, ki trajajo dlje kot po navadi, če se poškodujete,
English: Your doctor may prescribe a different dose if:
Slovenian: Zdravnik vam lahko predpiše drugačen odmerek:
English: Date of first authorisation: 16 December 2014 Date of last renewal:
Slovenian: Datum prve odobritve: 16. december 2014 Datum zadnjega podaljšanja:
English: For women with hormone dependent cancer, two non-hormonal contraceptive methods should be considered.
Slovenian: Pri ženskah s hormonsko odvisnim rakom je treba razmisliti o dveh nehormonskih načinih kontracepcije.
English: It is recommended that you record the date when the capsules are removed from refrigerator and the date after which they should be discarded.
Slovenian: Priporočamo vam, da si zabeležite datum, ko vzamete kapsule iz hladilnika, in datum, po katerem jih morate zavreči.
English: months 0 6 12 18 24 30 36 42 48 54 60 66 72 78 84 90 96 nolaparib nplacebo
Slovenian: meseci 0 6 12 18 24 30 36 42 48 54 60 66 72 78 84 90 96 nolaparib nplacebo
English: • every month for the first year of treatment
Slovenian: • vsak mesec med prvim letom zdravljenja,
English: June 2021
Slovenian: junija 2021
English: Your doctor may lower your dose or stop treatment, either for a short time or permanently.
Slovenian: Zdravnik vam lahko odmerek zmanjša ali zdravljenje prekine, bodisi za krajši čas bodisi trajno.
English: Based on stratified log-rank test.
Slovenian: Na podlagi stratificiranega log-rang testa.
English: Therefore, the specific dose recommendations for each formulation should be followed.
Slovenian: Zato je treba upoštevati specifična priporočila za odmerke za vsako posamezno obliko.
English: These changes were reversible within 4 weeks of cessation of dosing.
Slovenian: Te spremembe so bile reverzibilne v 4 tednih po prenehanju uporabe zdravila.
English: There were no confirmed responses in the comparator arm.
Slovenian: V primerjalni skupini ni bilo potrjenih odzivov.
English: Do not take a double dose (two doses at the same time) to make up for a forgotten dose.
Slovenian: Ne vzemite dvojnega odmerka (dva odmerka hkrati), če ste pozabili vzeti prejšnji odmerek.
English: These specific cancer cells can be identified by:
Slovenian: Te specifične rakave celice je mogoče prepoznati na podlagi:
English: Your doctor will tell you if there are any changes in your blood test that might need treatment.
Slovenian: Zdravnik vam bo povedal, ali imate v izvidih krvi kakšne spremembe, ki bi jih morda bilo treba zdraviti.
English: • a vaccine or a medicine that suppresses the immune system, as you may need to be closely monitored
Slovenian: • kakšno cepivo ali zdravilo, ki zavira imunski sistem, ker boste morda potrebovali skrbno spremljanje,
English: Exploratory analyses of TFST and TSST were also performed.
Slovenian: Izvedene so bile tudi eksplorativne analize TFST in TSST.
English: However, there was a slight reduction in embryofoetal survival.
Slovenian: Opazili pa so rahlo zmanjšanje embrio-fetalnega preživetja.
English: Uncommon side effects that may show up in blood tests: • increase in the size of red blood cells (not associated with any symptoms).
Slovenian: Občasni neželeni učinki, ki se lahko pokažejo na preiskavah krvi: • povečanje velikosti rdečih krvnih celic (to ni povezano z nobenimi simptomi).
English: HR= Hazard Ratio.
Slovenian: ROg = razmerje ogroženosti.
English: In particular, caution should be exercised if olaparib is administered in combination with any statin.
Slovenian: Še zlasti je previdnost potrebna, če se olaparib uporablja v kombinaciji s katerim koli statinom.
English: Chemotherapy n=97
Slovenian: kemoterapija n = 97
English: Confirmed responses (by BICR) were defined as a recorded response of either CR/PR, confirmed by repeat imaging not less than 4 weeks after the visit when the response was first observed.
Slovenian: Potrjeni odzivi (z BICR) so bili opredeljeni kot zabeležen CR ali PR, potrjen s ponovnim slikanjem ne prej kot 4 tedne po obisku, na katerem je bil odziv prvič opažen.
English: Other laboratory findings
Slovenian: Druge laboratorijske preiskave
English: • you have problems with your kidneys.
Slovenian: • če imate težave z ledvicami.
English: (events/patients)
Slovenian: (dogodki/bolnice)
English: Consistent results were observed in all predefined patient subgroups (see Figure 7).
Slovenian: Dosledne rezultate so opažali v vseh vnaprej določenih podskupinah bolnikov (glejte sliko 7).
English: months n-olaparib 74 n-placebo
Slovenian: meseci n-olaparib 74 n-placebo
English: • diarrhoea - if it gets severe, tell your doctor straight away.
Slovenian: • driska - če postane huda, morate to nemudoma povedati zdravniku.
English: INNER CARTON - with no blue box
Slovenian: NOTRANJA ŠKATLA - brez modrega okenca
English: (See previous paragraph: “Women of childbearing potential/contraception in females” for further information about birth control and pregnancy testing.)
Slovenian: (Za dodatne informacije o kontracepciji in testih nosečnosti glejte prejšnji odstavek “Ženske v rodni dobi/kontracepcija pri ženskah”.)
English: • if you are allergic to olaparib or any of the other ingredients of this medicine (listed in section 6)
Slovenian: • če ste alergični na olaparib ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
English: Seven patients, all stage IV, had no cytoreductive surgery.
Slovenian: Sedem bolnic, ki so vse imele stadij IV, ni imelo kirurške citoredukcije.
English: Antiemetic prophylaxis is not required.
Slovenian: Profilaksa z antiemetiki ni potrebna.
English: • Do not chew, crush, dissolve or divide the tablets as this may affect how quickly the medicine gets into your body.
Slovenian: • Tablet ne grizite, ne drobite, ne raztapljajte in ne lomite, ker lahko vse našteto vpliva na to, kako hitro zdravilo pride v telo.
English: Elimination Following a single dose of
Slovenian: Izločanje Po enkratnem odmerku
English: Study 19 (D0810C00019)
Slovenian: Študija 19 (D0810C00019)
English: Overall disease classification Metastatic
Slovenian: Celokupna klasifikacija bolezni Metastatska
English: If your blood count falls to a low level, you may need to have a blood transfusion (where you are given new blood or blood-based products from a donor).
Slovenian: Če se vam število krvnih celic preveč zmanjša, boste morda potrebovali transfuzijo krvi (pri kateri boste dobili novo kri ali krvne izdelke od krvodajalca).
English: Absence of fully functional HRR pathway is one of the key determinants of platinum sensitivity in ovarian and other cancers.
Slovenian: Odsotnost popolnoma funkcionalne poti HRR je eden ključnih dejavnikov občutljivosti na platino pri raku jajčnikov in drugih rakih.
English: ECOG performance status (%)
Slovenian: Stanje zmogljivosti po ECOG (%)
English: • increase in blood creatinine - this test is used to check how your kidneys are working.
Slovenian: • zvišanje kreatinina v krvi - ta preiskava se uporablja za preverjanje delovanja ledvic.
English: Many had also received other DNA damaging agents and radiotherapy.
Slovenian: Številne so prejemale tudi druga zdravila, ki okvarijo DNA, in radioterapijo.
English: Hard capsule 112 capsules
Slovenian: trda kapsula 112 kapsul
English: 27.9 (22.6-NR)
Slovenian: 27,9 (22,6-ND)
English: Number of patients at risk:
Slovenian: Število ogroženih bolnic:
English: Please tell your doctor if you are taking a hormonal contraceptive, as your doctor may recommend the addition of a non-hormonal contraceptive method.
Slovenian: Zdravnika morate obvestiti, če jemljete kakšen hormonski kontraceptiv: zdravnik vam bo morda svetoval, da dodatno uporabljate še nek nehormonski način kontracepcije.
English: • if you are breast-feeding (see section 2 below for more information).
Slovenian: • če dojite (za več informacij glejte poglavje 2, spodaj).
English: Any capsules that have been frozen must be discarded.
Slovenian: Kapsule, ki so bile zamrznjene, je treba zavreči.
English: Efficacy results are presented in Table 2 and Figures 1 and 2.
Slovenian: Rezultati učinkovitosti so prikazani v preglednici 2 in na slikah 1 in 2.
English: • Take one dose (8 capsules) of Lynparza by mouth with water, once in the morning and once in the evening.
Slovenian: • Zaužijte en odmerek (8 kapsul) zdravila Lynparza, z vodo, enkrat zjutraj in enkrat zvečer.
English: * Not controlled for multiplicity.
Slovenian: * Ni kontrolirano za večkratne primerjave.
English: • if you have low blood cell counts on testing.
Slovenian: • če imate na preiskavi majhno število krvnih celic.
English: Since it cannot be excluded that olaparib may reduce exposure to substrates of CYP2C9 through enzyme induction, the efficacy of some hormonal contraceptives may be reduced if co-administered with olaparib.
Slovenian: Ker ni mogoče izključiti, da olaparib zaradi indukcije encimov zmanjša izpostavljenost substratom CYP2C9, je možno, da se učinkovitost nekaterih hormonskih kontraceptivov med sočasno uporabo z olaparibom zmanjša.
English: Your doctor will test your blood every month for the first year of treatment and at regular intervals after that.
Slovenian: Zdravnik vam bo izvajal preiskave krvi vsak mesec prvo leto zdravljenja, pozneje pa v rednih presledkih.
English: • decrease in the number of platelets in blood (thrombocytopenia) - you may notice the following symptoms:
Slovenian: • zmanjšanje števila trombocitov v krvi (trombocitopenija) - opazite lahko naslednje simptome:
English: Do not take Lynparza:
Slovenian: Ne jemljite zdravila Lynparza:
English: • feeling short of breath, feeling very tired, pale skin or fast heart beat - these may be symptoms of a decrease in the number of red blood cells (anaemia).
Slovenian: • kratka sapa, občutek hude utrujenosti, bledica kože ali hitro bitje srca - to so lahko simptomi zmanjšanja števila rdečih krvnih celic (anemije).
English: The gBRCAm status of patients enrolled via local testing was confirmed retrospectively by central testing.
Slovenian: Status gBRCAm bolnic, vključenih z uporabo lokalnega testiranja, so retrospektivno potrdili s centralnim testiranjem.
English: • pain in the stomach area under the ribs (upper abdominal pain)
Slovenian: • bolečine v predelu želodca pod rebri (v zgornjem delu trebuha)
English: • allergic reactions (e.g. hives, difficulty breathing or swallowing, dizziness which are signs and symptoms of hypersensitivity reactions).
Slovenian: • alergijske reakcije (npr. koprivnica, težko dihanje ali požiranje, omotica, ki so znaki in simptomi preobčutljivostnih reakcij).
English: At the time of the PFS analysis, 1 patient had a confirmed partial response with a duration of response of 9.7 months in the olaparib arm.
Slovenian: Ob času analize PFS je imel 1 bolnik potrjen delen odziv s trajanjem odziva 9,7 meseca v skupini z olaparibom.
English: • You should not take Lynparza if you are pregnant or might become pregnant.
Slovenian: • Ne jemljite zdravila Lynparza, če ste noseči, ali če bi lahko zanosili.
English: Patients who had been treated with bevacizumab were excluded from the study, therefore there are no safety and efficacy data on olaparib patients who had previously received bevacizumab.
Slovenian: Bolnice, zdravljene z bevacizumabom, so bile izključene iz študije, zato podatkov o varnosti in učinkovitosti olapariba pri bolnicah, ki so predhodno prejemale bevacizumab, ni.
English: Genetic testing should be conducted by an experienced laboratory using a validated test.
Slovenian: Genetsko testiranje mora izvesti izkušen laboratorij z uporabo validiranega testa.
English: Lynparza should not be used during pregnancy.
Slovenian: Zdravila Lynparza se ne sme uporabljati med nosečnostjo.
English: NR (24.1-NR)
Slovenian: ND (24,1-ND)
English: This includes medicines obtained without a prescription and herbal medicines.
Slovenian: To velja tudi za zdravila, ki ste jih dobili brez recepta, in za zdravila rastlinskega izvora.
English: Instead, alternative and error-prone pathways are activated, such as the non-homologous end joining (NHEJ) pathway, leading to increased genomic instability.
Slovenian: Namesto tega se aktivirajo alternativne, napakam izpostavljene poti, npr. pot nehomolognega povezovanja koncev (NHEJ - non-homologous end joining), in to poveča genomsko nestabilnost.
English: The safety and efficacy of Lynparza in children and adolescents has not been established.
Slovenian: Varnost in učinkovitost zdravila Lynparza pri otrocih in mladostnikih nista bili dokazani.
English: Treatment with Lynparza should be initiated and supervised by a physician experienced in the use of anticancer medicinal products.
Slovenian: Zdravljenje z zdravilom Lynparza mora uvesti in nadzorovati zdravnik, ki ima izkušnje z uporabo zdravil proti raku.
English: • Take Lynparza once in the morning and once in the evening.
Slovenian: • Zdravilo Lynparza vzemite enkrat zjutraj in enkrat zvečer.
English: Patients who experience these symptoms should observe caution when driving or using machines.
Slovenian: Bolniki, ki imajo takšne simptome, morajo biti previdni glede vožnje in upravljanja strojev.
English: Patients in the olaparib group continued to receive treatment longer than those in the placebo group.
Slovenian: Bolnice v skupini z olaparibom so nadaljevale zdravljenje dalj časa kot tiste v skupini s placebom.
English: The major primary target organ for toxicity in both species was the bone marrow, with associated changes in peripheral haematology parameters.
Slovenian: Glavni ciljni organ toksičnosti je bil pri obeh živalskih vrstah kostni mozeg; to so spremljale spremembe perifernih hematoloških vrednosti.
English: Rarely, these may be a sign of more serious problems with the bone marrow such as ‘myelodysplastic syndrome' (MDS) or ‘acute myeloid leukaemia' (AML).
Slovenian: Redko je to lahko znak resnejših težav s kostnim mozgom, na primer "mielodisplastičnega sindroma" (MDS) ali "akutne mieloične levkemije" (AML).
English: New metastatic breast cancer (%) Hormone receptor status (%) HR+
Slovenian: Lokalno napredovala Nov metastatski rak dojk (%) Stanje hormonskih receptorjev (%) HR+
English: If you notice any side effects not listed in this leaflet, please contact your doctor straight away.
Slovenian: Če opazite kakšen neželen učinek, ki ni naveden v tem navodilu, se takoj posvetujte z zdravnikom.
English: Depending on the test used and the international classification consensus, the BRCA1/2 mutations have been classified as deleterious/suspected deleterious or pathogenic/likely pathogenic.
Slovenian: Odvisno od uporabljenega testa in mednarodnega klasifikacijskega soglasja so bile mutacije genov BRCA1/2 opredeljene kot škodljive/domnevno škodljive ali patogene/verjetno patogene.
English: In the absence of BRCA1 or BRCA2 mutations, HRR pathway may be compromised by other mechanisms, although the causative aberrancy and penetrance are not fully elucidated.
Slovenian: V odsotnosti mutacij gena BRCA1 ali BRCA2 lahko pot HRR okrnejo drugi mehanizmi, čeprav vzročna anomalija in penetrantnost nista povsem pojasnjeni.
English: Lynparza capsules can be stored for up to 3 months below 30°C.
Slovenian: Kapsule zdravila Lynparza je mogoče do 3 mesece shranjevati pri temperaturi do 30 °C.
English: Lynparza tablets should be swallowed whole and not chewed, crushed, dissolved or divided.
Slovenian: Tablete zdravila Lynparza je treba pogoltniti cele in se jih ne sme gristi, drobiti, raztapljati ali lomiti.
English: Previous anthracycline and taxane treatment
Slovenian: Predhodno zdravljenje z antraciklinom in taksanom
English: This clastogenicity is consistent with the known pharmacology of olaparib and indicates potential for genotoxicity in man.
Slovenian: Klastogenost se sklada z znano farmakologijo olapariba in kaže na potencialno genotoksičnost pri človeku.
English: In repeat-dose toxicity studies of up to 6 months duration in rats and dogs, daily oral doses of olaparib were well-tolerated.
Slovenian: V študiji toksičnosti ponavljajočih se odmerkov v trajanju do 6 mesecev pri podganah in psih so živali dobro prenašale vsakodnevno peroralno uporabo olapariba.
English: Therefore, an additional non-hormonal contraceptive method should be considered during treatment (see section 4.5).
Slovenian: Zato je treba razmisliti o dodatni nehormonski kontracepciji med zdravljenjem (glejte poglavje 4.5).
English: Ninety three percent (93%) of patients were randomised within 8 weeks of their last dose of platinum-based chemotherapy.
Slovenian: Triindevetdeset odstotkov (93 %) bolnic je bilo randomiziranih v 8 tednih po njihovem zadnjem odmerku kemoterapije na osnovi platine.
English: PFS (DCO 30 June
Slovenian: PFS (DCO 30. junij
English: Patients with evidence of disease at 2 years, who in the opinion of the treating physician can derive further benefit from continuous treatment, can be treated beyond 2 years.
Slovenian: Bolnice, ki imajo po 2 letih znake bolezni in bi jim nadaljevanje zdravljenja po mnenju lečečega zdravnika dodatno koristilo, lahko zdravljenje prejemajo več kot 2 leti.
English: Consistent results were observed in the subgroups of patients by evidence of the disease at study entry.
Slovenian: Pri podskupinah bolnic glede na dokaze bolezni ob vstopu v študijo so opažali dosledne rezultate.
English: The incidence of MDS/AML cases was similar among gBRCA1m and gBRCA2m patients (1.7% and 1.4%, respectively).
Slovenian: Pojavnost primerov MDS/AML je bila pri bolnicah z gBRCA1m in gBRCA2m podobna (1,7 % pri prvih in 1,4 % pri drugih).
English: On multiple dosing there is no marked accumulation, with steady state exposures achieved within ~3 to 4 days.
Slovenian: Po večkratnem odmerjanju ni izrazitega kopičenja in izpostavljenost v stanju dinamičnega ravnovesja je dosežena v ~3 do 4 dneh.
English: Clinical studies of olaparib in combination with other anticancer medicinal products, including DNA damaging agents, indicate a potentiation and prolongation of myelosuppressive toxicity.
Slovenian: Klinične študije olapariba v kombinaciji z drugimi zdravili proti raku, vključno z zdravili, ki poškodujejo DNA, kažejo na okrepitev in podaljšanje mielosupresivne toksičnosti.
English: • looking for faulty DNA repair genes, such as BRCA (BReast CAncer) genes.
Slovenian: • ugotavljanja okvarjenih genov za popravo DNA, na primer genov BRCA (BReast CAncer).
English: The potential for olaparib to induce CYP2C9, CYP2C19 and P-gp can also not be excluded.
Slovenian: Prav tako ni mogoče izključiti možnosti, da olaparib inducira CYP2C9, CYP2C19 in P-gp.
English: PARP inhibitors can destroy cancer cells that are not good at repairing DNA damage.
Slovenian: Zaviralci PARP lahko uničijo rakave celice, ki niso uspešne pri popravljanju okvare DNA.
English: • response to platinum chemotherapy, or
Slovenian: • odziva na kemoterapijo s platino ali
English: BOTTLE/LABEL
Slovenian: PLASTENKA/NALEPKA
English: The medicines listed here may not be the only ones that could affect Lynparza.
Slovenian: Tukaj našteta zdravila niso edina, ki lahko vplivajo na delovanje zdravila Lynparza.
English: Effect of olaparib on other medicinal products
Slovenian: Vpliv olapariba na druga zdravila
English: Therefore, olaparib upon co-administration may reduce the exposure to substrates of these metabolic enzymes and transport protein.
Slovenian: Zato lahko olaparib po sočasni uporabi zmanjša izpostavljenost substratom teh presnovnih encimov in prenašalne beljakovine.
English: The incidence of anaemia adverse reactions was 22.8% (CTCAE grade ≥3 7.4%).
Slovenian: Pojavnost neželenih učinkov z anemijo je bila 22,8 % (≥ 3. stopnje po CTCAE 7,4 %).
English: Treatment was continued until radiological progression of the underlying disease, unacceptable toxicity or for up to 2 years.
Slovenian: Zdravljenje se je nadaljevalo do radiološkega napredovanja osnovne bolezni, nesprejemljive toksičnosti ali do največ 2 leti.
English: Proportion of patients event free
Slovenian: Delež bolnic brez dogodka
English: • protease inhibitors boosted with ritonavir or cobicistat, boceprevir, telaprevir, nevirapine,
Slovenian: • zaviralce proteaz okrepljene z ritonavirjem ali kobicistatom, boceprevir, telaprevir, nevirapin,
English: These may be low counts for red or white blood cells or low platelet counts.
Slovenian: Lahko imate majhno število rdečih ali belih krvnih celic ali majhno število krvnih ploščic.
English: Chemotherapy (N = 97) Olaparib 300 mg twice daily (N = 205)
Slovenian: Kemoterapija (N = 97) Olaparib 300 mg dvakrat na dan (N = 205)
English: Detection of BRCA mutation
Slovenian: Ugotavljanje mutacije gena BRCA
English: Alu/Alu non-perforated blister containing 8 film-coated tablets.
Slovenian: Alu/Alu neperforirani pretisni omot z 8 filmsko obloženimi tabletami.
English: Levels appeared to return to normal after treatment discontinuation and did not appear to have any clinical consequences.
Slovenian: Vrednosti so se po prekinitvi zdravljenja normalizirale in po vsem sodeč ni bilo nobenih kliničnih posledic.
English: See section 4 for more information about these side effects, including the signs and symptoms you need to look out for (for example, fever or infection, bruising or bleeding).
Slovenian: Za informacije o teh neželenih učinkih glejte poglavje 4, vključno z znaki in simptomi, na katere morate biti pozorni (npr. vročina ali okužba, podplutbe ali krvavitev).
English: BRCA mutation status should be determined by an experienced laboratory using a validated test method (see section 5.1).
Slovenian: Mutacijsko stanje gena BRCA mora določiti izkušen laboratorij z validirano testno metodo (glejte poglavje 5.1).
English: • It is not known whether Lynparza passes into breast milk.
Slovenian: • Ni znano, ali zdravilo Lynparza prehaja v materino mleko.
English: The analysis was performed using a Cox proportional hazards model with factors for treatment, ethnic descent, platinum sensitivity and response to final platinum therapy.
Slovenian: Analiza je bila narejena s Coxovim modelom sorazmernih ogroženosti s faktorji za zdravljenje, etnično poreklo, občutljivost na platino in odziv na končno zdravljenje s platino.