FrancophonIA/ELRC3.0 huggingface dataset:
English: A matched-pair survival analysis of patients treated by Beromun and melphalan ILP as compared to a historical control failed to demonstrate any survival difference (p=0.5).
Croatian: Analiza preživljenja bolesnika liječenih izoliranom perfuzijom uda Beromunom i melfalanom u usporedbi s kontrolnom skupinom nije pokazala razliku u preživljenju (p=0,5).
English: Haematological disorders, in particular leukopaenia, thrombocytopaenia and clotting dysfunction, might be expected.
Croatian: Mogu se očekivati hematološki poremećaji, osobito leukopenija, trombocitopenija i poremećaji zgrušavanja.
English: The container contains latex rubber
Croatian: Spremnik sadrži lateks
English: Each vial contains 1 mg tasonermin*, corresponding to 3.0-6.0 x 107 IU (International Units).
Croatian: Svaka bočica sadrži 1 mg tasonermina*, što odgovara 3,0-6,0 x 107 IU (internacionalnih jedinica).
English: MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURER (S) RESPONSIBLE FOR BATCH RELEASE
Croatian: PROIZVOĐAČ BIOLOŠKE DJELATNE TVARI I PROIZVODAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET
English: Under conditions of greater than 2 % systemic leakage (observed in 13 of 51 patients) maximum systemic concentrations of tasonermin were still at least ten times lower than in the perfusion circuit.
Croatian: Pri sistemskom propuštanju većem od 2 % (u 13 od 51 bolesnika) maksimalne sistemske koncentracije tasonermina bile su još uvijek najmanje deset puta niže od onih u perfuzijskom krugu.
English: Each pack contains 4 vials of powder.
Croatian: Svako pakiranje sadrži 4 bočice praška.
English: For ILP, you will also receive other medicines to control pain, fever, blood pressure and blood clotting, as well as general anaesthesia.
Croatian: Tijekom izolirane perfuzije uda također ćete primiti druge lijekove, protiv bolova, vrućice, za kontrolu krvnog tlaka i zgrušavanja krvi, kao i opću anesteziju.
English: A dose-dependency has been observed as indicated by a decrease in clearance and an increase in half-life at increasing doses.
Croatian: Primijećena je ovisnost o dozi, izražena smanjenjem klirensa i povećanjem poluvijeka pri rastućim dozama.
English: Tasonermin does not cross the intact blood-brain barrier to a significant extent in mice.
Croatian: Tasonermin ne prolazi u značajnoj mjeri netaknutu krvno-moždanu barijeru kod miševa.
English: Each pack contains 4 vials.
Croatian: Svako pakiranje sadrži 4 bočice.
English: In the Rhesus monkey, whole body radiography following administration of radiolabelled tasonermin indicated no specific distribution pattern.
Croatian: Kod rezus majmuna radiografija cijelog tijela, nakon primjene radioaktivno obilježenog tasonermina, nije pokazala specifičan obrazac raspodjele.
English: Further, in addition to its direct effects, tasonermin modulates immune responses by inducing production of cytokines as well as low molecular weight mediators (prostaglandins, platelet activating factor).
Croatian: Nadalje, povrh svojih direktnih učinaka, tasonermin modulira imunološki odgovor putem indukcije stvaranja citokina kao i medijatora niske molekularne mase (prostaglandini, čimbenik aktivacije trombocita).
English: Significant hepatic dysfunction, e.g. > 2 x upper limits of normal levels of aspartate aminotransferase, alanine aminotransferase or alkaline phosphatase; or bilirubin levels > 1.25 x upper limits of normal.
Croatian: Značajna disfunkcija jetre, npr. > 2 x gornje granice normalnih vrijednosti aspartat aminotransferaze, alanin aminotransferaze ili alkalne fosfataze ili vrijednosti bilirubina > 1,25 x gornje granice normale.
English: The haematological changes included anaemia, increased haematocrit and increased or decreased leukocytes and platelets depending upon species and treatment duration.
Croatian: Hematološke promjene uključivale su anemiju, povećanje hematokrita te povećanje ili smanjenje leukocita i tromobocita, ovisno o vrsti i trajanju liječenja.
English: Each vial contains 20.12 mg (0.87 mmol) sodium.
Croatian: Svaka bočica sadrži 20,12 mg (0,87 mmol) natrija.
English: Perfusion level should be chosen to adequately encompass affected tissue (external iliac, common femoral, femoro-popliteal, popliteal, axillary and brachial being accepted routes) and catheters introduced.
Croatian: Potrebno je odabrati onu razinu perfuzije koja odgovara zahvaćenom tkivu (vanjski ilijačni, zajednički femoralni, femoro-poplitealni, poplitealni, aksilarni i brahijalni su standardni putevi) nakon čega se uvode kateteri.
English: It is not known whether tasonermin is excreted in human milk.
Croatian: Nije poznato izlučuje li se tasonermin u majčino mlijeko.
English: Each vial contains 1 mg tasonermin, corresponding to 3.0-6.0 x 107 IU.
Croatian: Svaka bočica sadrži 1 mg tasonermina, što odgovara 3,0-6.0 x 107 IU.
English: In the event of severe shock before the end of the ILP, the limb perfusion should be discontinued and appropriate therapy administered.
Croatian: U slučaju razvoja teškog šoka prije kraja izolirane perfuzije uda, perfuziju uda je potrebno prekinuti i uvesti odgovarajuću terapiju.
English: The content of one vial of Beromun powder should be reconstituted with 5.3 ml sterile 0.9% sodium chloride solution for injection.
Croatian: Sadržaj jedne bočice praška Beromun potrebno je rekonstituirati s 5,3 ml sterilne 0,9-postotne otopine natrijeva klorida za injekciju.
English: The synthesis capacity of the liver was lowered as indicated by increased liver enzymes.
Croatian: Kapacitet sinteze jetre bio je snižen, što se očitovalo povišenim vrijednostima jetrenih enzima.
English: At the end of the perfusion, the perfusate should be collected into the reservoir while washout fluid is added simultaneously to the circuit and circulated at the same flow rate of 35 to 40 ml/litre limb volume/minute.
Croatian: Na kraju perfuzije, perfuzat se prikuplja u spremnik, a istovremeno se u krug dodaje tekućina za ispiranje koja protječe istom brzinom od 35 do 40 ml/litri volumena uda/minuti.
English: The loco-regional application of Beromun, along with melphalan, has been shown to be highly effective for local control of irresectable soft tissue sarcomas of the limbs.
Croatian: Pokazalo se da je lokoregionalna primjena Beromuna, zajedno s melfalanom, vrlo učinkovita za postizanje lokalne kontrole neresektabilnog sarkoma mekog tkiva udova.
English: If Beromun dry powder or reconstituted solution should come into contact with the skin or mucous membranes, they should be washed thoroughly with water.
Croatian: Ako Beromun suhi prašak ili rekonstituirana otopina dođu u dodir s kožom ili sluznicama, potrebno je ispiranje obilnom količinom vode.
English: Symptoms of muscle damage at the perfused limb include pain, swelling, as well as neurological symptoms (e. g. paraesthesia, paralysis), all of which should be reported immediately to the attending doctor.
Croatian: Simptomi oštećenja mišića u perfundiranom udu uključuju bolove, otečenost, kao i neurološke simptome (npr. parestezije, paraliza), a sve je potrebno odmah prijaviti nadležnom liječniku.
English: After 30 minutes perfusion of Beromun alone, melphalan should be added as a bolus into the reservoir of the circuit, or slowly into the arterial line of the circuit.
Croatian: Nakon 30 minuta perfuzije samim Beromunom, dodaje se melfalan u obliku bolusa u spremnik kruga, ili polagano u arterijsku liniju kruga.
English: Potential leakage should be measured by radioactively labelled albumin or erythrocytes injected into the perfusion circuit, with appropriate measures for continuous monitoring of radioactivity leakage into the systemic circulation.
Croatian: Potencijalno propuštanje se mjeri radioaktivno obilježenim albuminom ili eritrocitima injiciranima u perfuzijski krug, s odgovarajućim mjerama za stalno mjerenje radioaktivnosti u sistemskoj cirkulaciji.
English: Blood, supplied with oxygen by a heart and lung machine, is pumped into your affected limb via a catheter in the main artery, while it is drained (pumped out) from the main vein.
Croatian: Krv, koja je opskrbljena kisikom pomoću uređaja „srce-pluća“, se ubacuje u bolesni ud putem katetera postavljenog u glavnu arteriju, a istovremeno se izbacuje iz glavne vene.
English: By reducing the size of the tumour, the treatment is intended to facilitate the removal of the tumor by surgery or to prevent severe damage to the surrounding healthy tissue and thus to delay or prevent the need for arm or leg amputation.
Croatian: Svrha liječenja je smanjenjem veličine tumora olakšati uklanjanje tumora kirurškim zahvatom ili spriječiti teško oštećenje okolnog zdravog tkiva, čime se odgađa ili sprječava potreba za amputacijom ruke ili noge.
English: Data obtained from 51 ILP patients demonstrated maximum concentrations of tasonermin in the perfusion circuit are reached 30 min after the onset of ILP and range between 3000 and 4000 ng/ml.
Croatian: Podaci dobiveni od 51 bolesnika pokazali su da se maksimalne koncentracije tasonermina u perfuzijskom kružnom protoku postižu 30 min nakon početka izolirane perfuzije uda te variraju između 3000 i 4000 ng/ml.
English: During the IPL and the seven to ten day period afterwards you will need to stay in hospital, your doctor will carefully monitor your blood pressure, circulation and any side effects.
Croatian: Tijekom izolirane perfuzije uda i u razdoblju od idućih sedam do deset dana nakon perfuzije morat ćete ostati u bolnici, uz pozoran liječnički nadzor krvnog tlaka, praćenja cirkulacije i uočavanja mogućih nuspojava.
English: Combinations with cardiotoxic substances (e.g. anthracyclines) should be avoided because it is possible that tasonermin could enhance cardiotoxicity, as has been observed in preclinical 13-week toxicological investigations (see section 4.4).
Croatian: Kombinacije s kardiotoksičnim tvarima (npr. antraciklini) se moraju izbjegavati jer postoji mogućnost da tasonermin može pojačati kardiotoksičnost, kao što je primijećeno u pretkliničkim toksikološkim istraživanjima u trajanju od 13 tjedana (vidjeti dio 4.4).
English: SPECIAL PRECAUTIONS FOR DISPOSAL OF UNUSED MEDICINAL PRODUCTS OR WASTE MATERIALS DERIVED FROM SUCH MEDICINAL PRODUCTS, IF APPROPRIATE
Croatian: POSEBNE MJERE ZA ZBRINJVANJE NEISKORIŠTENOG LIJEKA ILI OTPADNIH MATERIJALA KOJI POTJEČU
English: Upon reconstitution the product should be used immediately.
Croatian: Nakon rekonstitucije, lijek se mora odmah primijeniti.
English: Surgical resection of the tumour remnant should be undertaken whenever possible.
Croatian: Kirurška resekcija ostatnog tumora vrši se kada god je to moguće.
English: Beromun and then melphalan are injected into this circuit, over a total of 90 minutes the affected limb will be exposed to Beromun.
Croatian: Beromun, i zatim melfalan se injiciraju u ovaj kružni protok, a bolesni ud je izložen Beromunu tijekom ukupno 90 minuta.
English: The addition of interferon-gamma to the tasonermin perfusate seems not to be associated with significant increases in endogenous production of tasonermin or other inflammatory cytokines as shown in patients with severe trauma.
Croatian: Ne smatra se da je dodatak interferona-gama tasonermin perfuzatu povezan sa značajnim porastom endogenog stvaranja tasonermina ili drugih upalnih citokina kako je pokazano kod bolesnika s teškom traumom.
English: How to store Beromun
Croatian: Kako čuvati Beromun
English: There is no evidence that any of these agents counteracts the pharmacodynamic effects of tasonermin.
Croatian: Ne postoji dokaz da neki od ovih lijekova umanjuju farmakodinamične učinke tasonermina.
English: Proliferation of activated B- and T-lymphocytes, development of cytotoxic T-cells and immunoglobulin-secreting cells is enhanced, monocytes/macrophages are activated for killing of tumour cells, granulocytes are activated to display enhanced phagocytic activity, respiratory burst and degranulation, and adherence to endothelium.
Croatian: Pojačana je proliferacija aktiviranih B- i T-limfocita, razvoj citotoksičnih T-stanica i stanica koje izlučuju imunoglobulin, monociti/makrofazi se usmjeravaju na uništavanje tumorskih stanica, granulociti se aktiviraju i pokazuju pojačanu fagocitnu aktivnost, respiratorni prasak i degranulaciju te adheziju na endotel.
English: Beromun contains the active substance tasonermin (tumor necrosis factor alfa-1a), produced by recombinant DNA technology.
Croatian: Beromun sadrži djelatnu tvar tasonermin (čimbenik nekroze tumora α-1a), koji se proizvodi rekombinantnom DNA tehnologijom.
English: What you need to know before you use Beromun Do not use Beromun
Croatian: Što morate znati prije nego počnete primjenjivati Beromun
English: Eur J Cancer Clin Oncol 1982; 18: 905-910.
Croatian: Eur J Cancer Clin Oncol 1982; 18: 905-910.), a maksimalna doza iznosi 150 mg. 13 mg/l perfundiranog volumena gornjeg uda
English: ILP allows that tumour cells in your limb can be exposed to a very high dose of Beromun and melphalan, enhancing their anti-tumour effect, but without reaching the rest of the body, where they could cause serious side effects.
Croatian: Izolirani protok krvi uda omogućuje izlaganje tumorskih stanica u udu vrlo visokoj dozi Beromuna i melfalana, pojačavajući njihov antitumorski učinak, ali bez njihovog prelaska u ostatak organizma gdje bi mogli izazvati ozbiljne nuspojave.
English: This is to ensure optimal haemodynamic conditions and ensure a high urinary output, especially after the perfusion, to allow for rapid clearance of any residual tasonermin.
Croatian: Time se osiguravaju optimalni hemodinamski uvjeti i obilna diureza osobito nakon perfuzije, kako bi se omogućio brz klirens preostalog tasonermina.
English: After connection of the limb to the isolated circuit, flow rate should be adjusted to 35 to 40 ml/litre limb volume/minute and leakage from limb to systemic circulation checked using a radioactive tracer technique (see section 4.4).
Croatian: Nakon spajanja uda na izolirani krug, brzinu protoka potrebno je namjestiti na 35 do 40 ml/litri volumena uda/minuti, dok se propuštanje lijeka iz uda u sistemsku cirkulaciju provjerava pomoću metode radioaktivnog indikatora (vidjeti dio 4.4).
English: Significant renal dysfunction, e.g. nephrotic syndrome, serum creatinine > 150 µmol/l, or creatinine clearance of < 50 ml/min.
Croatian: Značajna disfunkcija bubrega, npr. nefrotski sindrom, kreatinin u serumu > 150 µmol/l ili klirens kreatinina < 50 ml/min.
English: The duration of the perfusion including melphalan should be 60 minutes.
Croatian: Perfuzija melfalanom treba trajati 60 minuta.
English: Beromun has been co-administered with interferon-gamma in the ILP setting but no added value has been demonstrated.
Croatian: Beromun je istovremeno primjenjivan s interferonom-gama u postupku izolirane perfuzije uda, ali nije pokazana dodana vrijednost.
English: Not relevant
Croatian: Nije značajno
English: In the Rhesus monkey, pharmacokinetic studies following intravenous injection of tasonermin indicated a non-specific, non-saturable excretion via glomerular filtration in the kidney.
Croatian: Kod rezus majmuna, farmakokinetička ispitivanja nakon intravenske injekcije tasonermina ukazala su na nespecifično, nesaturabilno izlučivanje putem glomerularne filtracije u bubregu.
English: No significant interactions have so far been noted, but caution should be exercised (see section 4.4).
Croatian: Do sada nisu zabilježene značajne interakcije, ali je potreban oprez (vidjeti dio 4.4).
English: Extremity necrosis, severe enough to warrant amputation
Croatian: Nekroza ekstremiteta, dovoljno teška da je amputacija opravdana
English: - if you are breast-feeding, you must stop for at least seven days after receiving Beromun
Croatian: - ako ste trudni ili planirate zatrudnjeti. - ako dojite, morate prekinuti dojenje najmanje idućih sedam dana nakon primjene Beromuna.
English: Renal and hepatic function should be closely monitored.
Croatian: Bubrežnu i jetrenu funkciju potrebno je pažljivo pratiti.
English: How to use Beromun
Croatian: Kako primjenjivati Beromun
English: Under conditions of less than 2% systemic leakage (observed in 38 of 51 patients), maximum systemic circulation concentrations of tasonermin were reached 5 min after the start of ILP and are approximately 200 times less than in the perfusion circuit.
Croatian: Pri sistemskom propuštanju manjem od 2 % (u 38 od 51 bolesnika), maksimalne sistemske koncentracije tasonermina u cirkulaciji postignute su 5 min nakon početka perfuzije te su oko 200 puta manje nego u perfuzijskom krugu.
English: No significant interactions have so far been noted, but caution should be exercised (see section 4.5).
Croatian: Do sada nisu zabilježene značajne interakcije, ali je potreban oprez (vidjeti dio 4.5).
English: However, should this occur, your doctor will immediately wash out your affected limb to remove Beromun, and the ILP will be stopped.
Croatian: Međutim, ako do njega ipak dođe, liječnik će Vam odmah isprati bolesni ud radi uklanjanja Beromuna, a izolirani protok krvi uda će prekinuti.
English: In such cases, a standard wash-out procedure should follow, using at least 2 litres of dextran 70 intravenous infusion or similar fluid.
Croatian: U takvim slučajevima treba slijediti standardni postupak ispiranja, uz uporabu najmanje 2 litre intravenske infuzije dekstrana 70 ili slične tekućine.
English: To cover the intended clinical use of Beromun, ILP experiments were performed in hind legs of healthy rats using different doses in the same tasonermin concentration as in the clinical situation in the human.
Croatian: Kako bi se što vjernije oponašali uvjeti kliničke primjene Beromuna, izolirana perfuzija uda je u pokusima rađena na stražnjim nogama zdravih štakora uz uporabu različitih doza u istoj koncentraciji tasonermina kao u kliničkoj situaciji kod ljudi.
English: Should accidental overdose occur, ILP should be terminated immediately and the limb washed out using at least 2 litres of dextran 70 intravenous infusion or similar fluid (see also section 4.4).
Croatian: Ako dođe do slučajnog predoziranja, izoliranu perfuziju uda se mora odmah prekinuti, a ud isprati uz uporabu najmanje 2 litre intravenske infuzije dekstrana 70 ili slične tekućine (također vidjeti dio 4.4).
English: Leukopenia, thrombocytopenia
Croatian: Leukopenija, trombocitopenija
English: In addition, as the clinical situation dictates, a vasopressor agent, e.g. dopamine, can be considered for administration during the ILP procedure, as well as in the post-operative period.
Croatian: Nadalje, u skladu s razvojem kliničke slike može se razmotriti primjena vazopresornog agensa, npr. dopamina, tijekom izolirane perfuzije uda, kao i u postoperativnom razdoblju.
English: Concurrent administration of agents likely to cause significant hypotension is not recommended (see section 4.5).
Croatian: Istovremena primjena lijekova za koje se smatra da izazivaju značajnu hipotenziju se ne preporučuje (vidjeti dio 4.5).
English: Beromun is used, together with melphalan containing medicine, for the treatment of soft tissue sarcoma of the arms and legs.
Croatian: Beromun se primjenjuje zajedno s lijekom koji sadrži melfalan za liječenje sarkoma mekog tkiva ruku i nogu.
English: At ILP, no incompatibilities with other constituents of the perfusate, with hyperthermia or with the membrane oxygenator and the silicone tubing are known.
Croatian: Pri izoliranoj perfuziji ekstremiteta nisu poznate inkompatibilnosti s drugim sastavnicama perfuzata, uz hipertermiju ili uz primjenu membranskog oksigenatora i silikonske cijevi.
English: Combinations with cardiotoxic substances (e.g. anthracyclines) should be avoided because it is possible that tasonermin could enhance cardiotoxicity, as has been observed in preclinical 13-week toxicological investigations.
Croatian: Potrebno je izbjegavati kombinacije s kardiotoksičnim tvarima (npr. antraciklini) jer postoji mogućnost da tasonermin pojačava kardiotoksičnost, što je primijećeno u pretkliničkim toksikološkim istraživanjima u trajanju od 13 tjedana.
English: The maximum tolerated dose (MTD) of tasonermin for ILP is 4 mg, which is 10 times the systemic MTD.
Croatian: Maksimalna podnošljiva doza tasonermina za izoliranu perfuziju uda je 4 mg, što je 10 puta više nego sistemska maksimalna podnošljiva doza.
English: Late onset of peripheral arterial occlusive disease (PAOD) of the lower limbs has been reported in patients several years after ILP, predominantly in patients presenting with established cardiovascular risk factors, or who had undergone additional irradiation therapy of the concerned limb.
Croatian: Kasni nastup periferne arterijske okluzivne bolesti donjih udova uočen je u bolesnika nekoliko godina nakon izolirane perfuzije uda, uglavnom u bolesnika s utvrđenim kardiovaskularnim rizičnim čimbenicima, ili koji su bili dodatno podvrgnuti radioterapiji tog uda.
English: If you do, this will not be until at least six weeks after your first ILP.
Croatian: Ako do toga ipak dođe, mora proći najmanje šest tjedana nakon prvog izoliranog protoka krvi uda.
English: Direct inhibition of tumour cell proliferation: Tasonermin is cytotoxic or cytostatic in vitro for a variety of tumour cell lines of different histogenesis.
Croatian: Direktna inhibicija proliferacije tumorskih stanica: Tasonermin je citotoksičan ili citostatičan in vitro za razne tumorske stanice različite histogeneze.
English: Wash-out should continue until a clear (pink, transparent) venous outflow is obtained.
Croatian: Ispiranje se nastavlja dok se ne postigne čisti (ružičast, proziran) povrat iz vene.
English: Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Croatian: Lijek se izdaje na ograničeni recept. (vidjeti Prilog I: Sažetak opisa svojstava lijeka, dio 4.2)
English: Do not use this medicine after the expiry date which is stated on the carton and vial label after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici iza „Rok valjanosti“/EXP.
English: External heat loss from the limb should be prevented by application of thermal blankets and limb temperature continuously monitored by thermistor probes inserted into subcutaneous tissue and muscle.
Croatian: Vanjski gubitak topline iz uda potrebno je spriječiti primjenom termalnih deka, a temperaturu uda stalno pratiti pomoću temperaturnih sondi umetnutih u potkožno tkivo i mišić.
English: You may have to stay in an intensive care unit (ICU) directly after the ILP for a short time.
Croatian: Možda ćete kratko vrijeme morati boraviti u jedinici za intenzivno liječenje odmah nakon izolirane perfuzije uda.
English: Hand and foot, if not affected, should be protected by Esmarch (expulsion) bandages.
Croatian: Ako šaka i stopalo nisu zahvaćeni, potrebno ih je zaštititi Esmarchovim (ekspulzijskim) zavojima.
English: 10 mg/l perfused lower limb volume
Croatian: 10 mg/l perfundiranog volumena donjeg uda
English: Sepsis Blood and lymphatic system disorders Common:
Croatian: Poremećaji krvi i limfnog sustava Često:
English: The resulting solution will be administered into an artery in your affected arm or leg by ILP for an initial period of 30 minutes.
Croatian: Dobivena otopina se unosi u arteriju bolesne ruke ili noge putem izolirane perfuzije uda tijekom početnog trajanja 30 minuta.
English: A number of therapeutic measures are routinely used during the ILP and in the immediate post-operative period.
Croatian: Određene terapijske mjere se rutinski primjenjuju tijekom izolirane perfuzije uda i odmah u postoperativnom razdoblju.
English: Upper limb: 3 mg total dose by ILP Lower limb: 4 mg total dose by ILP
Croatian: Gornji udovi: 3 mg ukupna doza izoliranom perfuzijom uda Donji udovi: 4 mg ukupna doza izoliranom perfuzijom uda
English: The recommended dose of Beromun depends on the affected limb, usually 3 mg for the arm and 4 mg for the leg. Beromun powder has to be dissolved before use.
Croatian: Preporučena doza Beromuna ovisi o bolesnom udu, obično iznosi 3 mg za ruku i 4 mg za nogu.
English: A Swan-Ganz catheter may be considered for monitoring pulmonary artery pressure and wedge pressure during the ILP and in the post-operative period.
Croatian: Može se postaviti Swan-Ganzov kateter radi praćenja plućnog arterijskog tlaka i plućnog kapilarnog tlaka tijekom izolirane perfuzije uda i u postoperativnom razdoblju.