FrancophonIA/ELRC3.0 huggingface dataset:
English: An average of only 0.3% of the intravenous dose was excreted in urine as inhibitors.
Slovenian: V urinu se v obliki zaviralcev v povprečju izloči samo 0,3 % intravenskega odmerka.
English: • you are taking or, in the last 7 days, have taken or been given a medicine called fusidic acid (a medicine for bacterial infection)
Slovenian: • jemljete ali ste v zadnjih sedmih dneh jemali zdravilo, imenovano fusidna kislina (zdravilo za bakterijske okužbe),
English: Therefore, fenofibrate in Cholib may be taken without regard to meals.
Slovenian: Zato se lahko fenofibrat v zdravilu Cholib vzame ne glede na obroke.
English: • rashes, itching, red patches on the skin.
Slovenian: • izpuščaj, srbenje, rdeče lise na koži,
English: Niacin (nicotinic acid)
Slovenian: Niacin (nikotinska kislina)
English: Week 12 to Week 24
Slovenian: 12. do 24. teden
English: The amount recovered in the faeces represents absorbed medicinal product equivalents excreted in bile as well as unabsorbed medicinal product.
Slovenian: Količina, ki je jo zaznamo v blatu, predstavlja ekvivalente absorbiranega zdravila, izločenega v žolču, ter neabsorbirano zdravilo.
English: • poor memory or memory loss
Slovenian: • motnje spomina ali izguba spomina,
English: Treatment Group
Slovenian: Skupina zdravljenja
English: HDL cholesterol is often called ‘good' cholesterol because it helps keep the ‘bad' cholesterol from building up in the arteries and because it protects against heart disease.
Slovenian: Holesterol HDL pogosto imenujemo „dobri“ holesterol, ker pomaga preprečevati kopičenje „slabega“ holesterola v arterijah in ker varuje pred boleznimi srca.
English: Based on the results of the SEARCH trial, homozygote C allele carriers (also called CC) treated with 80 mg have a 15% risk of myopathy within one year, while the risk in heterozygote C allele carriers (CT) is 1.5%.
Slovenian: Na osnovi rezultatov preskušanja SEARCH imajo homozigotni nosilci alela C (imenovanega tudi CC), zdravljeni z 80 mg, 15-odstotno tveganje za miopatijo v enem letu, tveganje pri heterozigotnih nosilcih alela C (CT) pa je 1,5 %.
English: Gemfibrozil, Other statins and fibrates
Slovenian: Gemfibrozil, drugi statini in fibrati
English: • low red blood cell count (anaemia)
Slovenian: • nizko število rdečih krvničk (anemija),
English: • If you are allergic to peanut, arachis oil, soya lecithin or related substances
Slovenian: • če ste alergični na arašide, arašidovo olje, sojin lecitin ali sorodne snovi,
English: • a serious allergic reaction which causes difficulty in breathing or dizziness (anaphylaxis) (very rare)
Slovenian: • resna alergijska reakcija, ki povzroča težave pri dihanju ali omotico (anafilaksija) (zelo redki),
English: Frequency categories are based on information available from simvastatin and fenofibrate Summary of Product Characteristics available in the EU.
Slovenian: Kategorije pogostnosti temeljijo na podatkih, ki so razpoložljivi iz povzetkov glavnih značilnosti zdravil v EU, ki vsebujejo simvastatin in fenofibrat.
English: If Creatine Kinase levels are significantly elevated at baseline (> 5 x ULN), treatment should not be started.
Slovenian: Če so ravni kreatin-kinaze pomembno zvišane v izhodišču (> 5-kratnik ULN), zdravljenja ne smete uvesti.
English: At maximally tolerated doses in both the rat and the rabbit, simvastatin produced no fetal malformations, and had no effects on fertility, reproductive function or neonatal development.
Slovenian: Pri največjih odmerkih, ki jih še prenašajo podgane in kunci, simvastatin ni povzročil malformacij ploda, učinka na plodnost, reprodukcijsko funkcijo ali neonatalni razvoj.
English: Grapefruit juice should be avoided (see section 4.5).
Slovenian: Izogibati se je treba uživanju grenivkinega soka (glejte poglavje 4.5).
English: This leaflet was last revised in <{MM/YYYY}>.
Slovenian: Navodilo je bilo nazadnje revidirano dne {MM/LLLL}
English: This medicinal product contains sunset yellow FCF (E110) that may cause allergic reactions.
Slovenian: To zdravilo vsebuje barvilo sončno rumeno FCF (E110), ki lahko povzroči alergijske reakcije.
English: Creatine Kinase should not be measured following strenuous exercise or in the presence of any plausible alternative cause of Creatine Kinase increase as this makes value interpretation difficult.
Slovenian: Kreatin-kinaze ne merite po naporni telesni vadbi ali v prisotnosti katerega koli morebitnega drugega vzroka zvišanja ravni kreatin-kinaze, saj to zelo oteži interpretacijo.
English: Do not take fusidic acid (a medicine for bacterial infections) while using this medicine.
Slovenian: Med jemanjem tega zdravila ne jemljite fusidne kisline (zdravilo za bakterijske okužbe).
English: Animal studies have shown embryo-toxic effects at doses in the range of maternal toxicity (see section 5.3).
Slovenian: Študije pri živalih so pokazale embriotoksične učinke odmerkov v razponu toksičnosti pri materi (glejte poglavje 5.3).
English: The overall effect is a decrease in the ratio of low and very low-density lipoproteins to high-density lipoproteins.
Slovenian: Skupni učinek je znižanje razmerja med lipoproteini nizke gostote in zelo nizke gostote ter lipoproteini visoke gostote.
English: Posology The recommended dose is one tablet per day.
Slovenian: Priporočeni odmerek je ena tableta na dan.
English: Caution should be exercised in patients with pre-disposing factors for rhabdomyolysis.
Slovenian: Previdnost je potrebna pri bolnikih z dejavniki nagnjenosti k rabdomiolizi.
English: • Hypoalbuminaemia
Slovenian: • Hipoalbuminemija
English: ANCOVA (analysis of covariance) of Percent Change in TC, non-HDL-C, ApoAI, ApoB, ApoB/ApoAI and fibrinogen from Baseline to 24 Weeks - Full Analysis Subject Sample Parameter
Slovenian: ANCOVA (analiza kovariance) odstotne spremembe skupnega holesterola, ne-HDL-holesterola, ApoAI, ApoB, ApoB/ApoAI in fibrinogena po 24 tednih od izhodišča - celotna analiza vzorca preiskovancev
English: LDL and VLDL triglycerides are reduced.
Slovenian: Ravni LDL- in VLDL-trigliceridov se znižajo.
English: Statin therapy may be re-introduced seven days after the last dose of fusidic acid.
Slovenian: Zdravljenje s statini se lahko nadaljuje sedem dni po zadnjem odmerku fusidne kisline.
English: Pancreatitis has been reported in patients taking fenofibrate (see sections 4.3 and 4.8).
Slovenian: Poročali so o pankreatitisu pri bolnikih, ki jemljejo fenofibrat (glejte poglavji 4.3 in 4.8).
English: • infection of the upper respiratory tract
Slovenian: • okužba zgornjih dihal.
English: Therapy with Cholib should be temporarily stopped a few days prior to elective major surgery and when any major medical or surgical condition supervenes.
Slovenian: Zdravljenje z zdravilom Cholib je treba začasno prekiniti nekaj dni pred načrtovanim velikim kirurškim posegom ali če se nepričakovano pojavi pomembno bolezensko ali kirurško stanje.
English: If you get pregnant while taking Cholib, stop taking it immediately and contact your doctor.
Slovenian: Če zanosite med zdravljenjem z zdravilom Cholib, nemudoma prekinite jemanje in se posvetujte s svojim zdravnikom.
English: Treatment with simvastatin must be suspended for the duration of pregnancy or until it has been determined that the woman is not pregnant.
Slovenian: Zdravljenje s simvastatinom je treba začasno prekiniti za čas nosečnosti ali do izključitve nosečnosti.
English: Fenofibrate and simvastatin are not inhibitors of CYP 2D6, CYP 2E1, or CYP 1A2.
Slovenian: Fenofibrat in simvastatin nista zaviralca CYP 2D6, CYP 2E1 ali CYP 1A2.
English: Another prespecified subgroup analysis identified a statistically significant treatment-by-gender interaction (p=0.01) indicating a possible treatment benefit of combination therapy in men (p=0.037) but a potentially higher risk for the primary outcome in women treated with combination therapy compared to simvastatin monotherapy (p=0.069).
Slovenian: V drugi analizi vnaprej določene podskupine so ugotovili statistično pomembno interakcijo med zdravljenjem in spolom (p = 0,01), ki kaže morebitno korist zdravljenja s kombinacijo pri moških (p = 0,037), vendar možno večje tveganje za primarni izid pri ženskah, ki so se zdravile s kombinacijo, v primerjavi z zdravljenjem samo s simvastatinom (p = 0,069).
English: In addition, simvastatin moderately increases HDL-C and reduces plasma TG.
Slovenian: Poleg tega simvastatin zmerno zviša HDL-holesterol in zniža plazemske ravni TG.
English: Carriers of the SLCO1B1 gene c.521T>C allele have lower OATP1B1 activity.
Slovenian: Nosilci alela c.521T>C gena SLCO1B1 imajo manjšo aktivnost OATP1B1.
English: Monitor patients for any signs and symptoms of muscle pain, tenderness or weakness
Slovenian: Bolnike spremljajte za znake in simptome mišičnih bolečin, občutljivosti ali šibkosti.
English: In most people, there are no signs of cholesterol or triglycerides problems at first.
Slovenian: Pri večini ljudi nenormalna raven holesterola ali trigliceridov sprva ne povzroča nobenih bolezenskih znakov.
English: • hypersensitivity (allergic) reactions including swelling of the face, tongue and throat which may cause difficulty in breathing (angioedema) (rare)
Slovenian: • preobčutljivostne (alergijske) reakcije, vključno z/s: otekanjem obraza, jezika in grla, kar lahko povzroči težave pri dihanju (angioedem) (redki),
English: • Concomitant administration of fibrates, statins, danazol, ciclosporin or potent cytochrome
Slovenian: • Sočasna uporaba fibratov, statinov, danazola, ciklosporina ali močnih zaviralcev citokroma
English: Consult the prescribing information of all concomitantly used drugs to obtain further information about their potential interactions with simvastatin and/or the potential for enzyme or transporter alterations and possible adjustments to dose and regimens.
Slovenian: Glejte navodila za predpisovanje vseh sočasno uporabljenih zdravil, da se boste dobili več informacij o morebitnem medsebojnem delovanju teh zdravil s simvastatinom in/ali o možnosti spreminjanja encimov ali prenašalcev, dobili pa boste tudi več informacij o morebitnih prilagoditvah odmerkov in režimov.
English: Although the mechanism is not fully understood, ciclosporin has been shown to increase the plasma exposure (AUC) to simvastatin acid, presumably due in part to inhibition of CYP 3A4 and OATP-1B1 transporter.
Slovenian: Čeprav mehanizem ni popolnoma pojasnjen, so dokazali, da ciklosporin poveča plazemsko izpostavljenost (AUC) simvastatinski kislini, verjetno delno zaradi zaviranja CYP 3A4 in prenašalca OATP-1B1.
English: Do not take Cholib if any of above applies to you.
Slovenian: Zdravila Cholib ne smete jemati, če se kaj od zgoraj naštetega nanaša na vas.
English: • feeling exhausted (astenia)
Slovenian: • utrujenost (astenija),
English: In patients with SLCO1B1 polymorphism there is a risk of increased exposure of simvastatin, which may lead to an increased risk of rhabdomyolysis (see section 4.4).
Slovenian: Pri bolnikih s polimorfizmom SLCO1B1 obstaja tveganje za povečano izpostavljenost simvastatinu, ki lahko privede do zvečanega tveganja za rabdomiolizo (glejte poglavje 4.4.
English: In such situations, the risk of treatment should be considered in relation to possible benefit, and clinical monitoring is recommended.
Slovenian: V teh primerih je treba pretehtati tveganje zdravljenja v primerjavi z možno koristjo.
English: • you or a close family member have a muscle problem which runs in the family
Slovenian: • imate sami ali bližnji družinski član mišično bolezen, ki je dedna,
English: Cholib contains soya lecithin.
Slovenian: Zdravilo Cholib vsebuje sojin lecitin.
English: • Hypersensitivity to the active substances, peanut, soya or to any of the excipients listed in section 6.1 (see also section 4.4)
Slovenian: • Preobčutljivost na učinkovini, arašide, sojo ali katero koli pomožno snov, navedeno v poglavju 6.1 (glejte tudi poglavje 4.4)
English: The major metabolites of simvastatin present in human plasma are the beta-hydroxyacid and four additional active metabolites.
Slovenian: Poglavitni presnovki simvastatina v človeški plazmi so betahidroksi kislina in še štirje drugi aktivni presnovki.
English: The risk of muscle toxicity may be increased if Cholib is administered with another fibrate, statin, niacin, fusidic acid or other specific concomitant substances (for specific interactions see section 4.5).
Slovenian: Tveganje toksičnosti za mišičje se lahko poveča, če se zdravilo Cholib daje z drugim fibratom, statinom, niacinom, fusidno kislino ali drugimi specifičnimi snovmi (za specifične interakcije glejte poglavje 4.5).
English: Pharmacotherapeutic group: Lipid modifying substances, HMG-CoA reductase inhibitors in combination with other lipid modifying substances, ATC code: C10BA04
Slovenian: Farmakoterapevtska skupina: zdravila za spreminjanje ravni serumskih lipidov, zaviralci reduktaze HMG-CoA v kombinaciji z drugimi zdravili za spreminjanje serumske ravni lipidov, oznaka ATC: C10BA04
English: Prescribing recommendations for interacting substances are summarised in the table below (see also sections 4.2 and 4.3).
Slovenian: Priporočila za predpisovanje zdravil, ki lahko privedejo do interakcij, so povzeta v spodnji preglednici (glejte tudi poglavja 4.2 in 4.3).
English: What Cholib is and what it is used for What you need to know before you take Cholib How to take Cholib
Slovenian: Kaj je zdravilo Cholib in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Cholib Kako jemati zdravilo Cholib Možni neželeni učinki
English: Response to therapy should be monitored by determination of serum lipid values (total cholesterol (TC), LDL-C, triglycerides (TG)).
Slovenian: Odziv na zdravljenje je treba spremljati z določanjem ravni lipidov v serumu (skupni holesterol (TC), LDL-holesterol, trigliceridi (TG)).
English: LDL is formed from very-low-density protein (VLDL) and is catabolised predominantly by the high affinity LDL receptor.
Slovenian: LDL se tvori iz proteinov zelo nizke gostote (VLDL) in katabolizira predvsem preko visokoafinitetnega receptorja LDL.
English: Kinetic studies following the administration of a single dose and continuous treatment have demonstrated that the drug does not accumulate.
Slovenian: V študijah kinetike po dajanju enega odmerka in neprekinjenega zdravljenja so dokazali, da se zdravilo ne kopiči.
English: Do not exceed one Cholib 145 mg/20 mg per day, unless clinical benefit outweigh the risk
Slovenian: Ne smete preseči odmerka ene tablete zdravila Cholib 145 mg/20 mg na dan, razen če klinična korist odtehta tveganje.
English: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) lipid trial was a randomized placebo-controlled study of 5,518 patients with type 2 diabetes mellitus treated with fenofibrate in addition to simvastatin.
Slovenian: Preskušanje za lipide Action to Control Cardiovascular Risk in Diabetes (ACCORD) je bila randomizirana, s placebom kontrolirana študija 5518 bolnikov s sladkorno boleznijo tipa 2, ki so bili zdravljeni s fenofibratom in simvastatinom.
English: They are both used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood.
Slovenian: Obe učinkovini se uporabljata za nižanje ravni skupnega holesterola, „slabega“ holesterola (holesterola LDL) in maščobnih snovi v krvi, imenovanih trigliceridi.
English: Therefore, close clinical monitoring of such patients taking colchicine and Cholib is advised.
Slovenian: Zato je priporočljivo natančno spremljanje bolnikov, ki jemljejo kolhicin in zdravilo Cholib.
English: • If you have liver or gallbladder problems
Slovenian: • če imate težave z jetri ali žolčnikom,
English: • Known photoallergy or phototoxic reaction during treatment with fibrates or ketoprofen
Slovenian: • Znana alergija na svetlobo ali fototoksična reakcija med zdravljenjem s fibrati ali ketoprofenom
English: Fenofibrate is a fibric acid derivative whose lipid modifying effects reported in humans are mediated via activation of Peroxisome Proliferator Activated Receptor type alpha (PPAR).
Slovenian: Fenofibrat je derivat fibrinske kisline, katerega učinek spreminjanja ravni lipidov pri človeku naj bi posredovala aktivacija s peroksisomskim proliferatorjem aktiviranega receptorja tipa alfa (PPARα).
English: If the dose of Cholib is changed or discontinued, the same procedure should be repeated.
Slovenian: Če odmerek zdravila Cholib spremenite ali zdravljenje prekinete, spet izvedite ta postopek.
English: There are no clinical data on fertility from the use of Cholib.
Slovenian: Kliničnih podatkov o plodnosti pri uporabi zdravila Cholib ni.
English: This adverse reaction should be taken into account when driving vehicles or using machines under Cholib therapy.
Slovenian: Ta neželeni učinek je treba upoštevati pri vožnji in upravljanju s stroji med zdravljenjem z zdravilom Cholib.
English: Cholib must not be given to children and adolescents (age below 18 years).
Slovenian: Otroci in mladostniki (mlajši od 18 let) ne smejo jemati zdravila Cholib.
English: Sleep disorder, including nightmares, depression not known
Slovenian: Psihiatrične motnje nespečnost zelo redki motnje spanja, vključno z nočnimi morami, depresija neznana
English: Patients receiving co-administration of Cholib and drugs metabolised by CYP 2C19, CYP 2A6, or especially CYP 2C9 with a narrow therapeutic index should be carefully monitored and, if necessary, dose adjustment of these drugs is recommended.
Slovenian: Priporočljivo je, da se bolnike, ki sočasno uporabljajo zdravilo Cholib in zdravila, ki se presnavljajo s CYP 2C19, CYP 2A6 in zlasti CYP 2C9 z ozkim terapevtskim indeksom, natančno spremlja in se jim po potrebi prilagodi odmerek teh zdravil.
English: There have been reports of rhabdomyolysis (including some fatalities) in patients receiving a statin in combination with fusidic acid (see section 4.5).
Slovenian: Obstajajo poročila o rabdomiolizi (tudi o nekaj smrtnih primerih) pri bolnikih, ki so prejemali statin v kombinaciji s fusidno kislino (glejte poglavje 4.5).
English: Through activation of PPAR, fenofibrate activates lipoprotein lipase production and reduces production of apoprotein CIII.
Slovenian: Fenofibrat preko aktivacije PPARα sproži tvorbo lipoproteinske lipaze in zmanjša tvorbo apoproteina CIII.
English: Other medicines and Cholib:
Slovenian: Druga zdravila in zdravilo Cholib
English: Fibrinogen* (g/L) Feno 145 + Simva 40
Slovenian: Fibrinogen* (g/l) feno 145 +
English: • Known gallbladder disease
Slovenian: • Znana bolezen žolčnika
English: If you have taken more Cholib than you should or if someone else has taken your medicine, tell your doctor or pharmacist or contact your nearest hospital
Slovenian: Če ste vzeli večji odmerek zdravila Cholib, kot bi smeli Če ste vzeli večji odmerek zdravila Cholib, kot bi smeli, ali če kdo drug vzame vaše zdravilo, se posvetujte s svojim zdravnikom, farmacevtom ali najbližjo bolnišnico.
English: Gemfibrozil increases the AUC of simvastatin acid by 1.9-fold, possibly due to inhibition of the glucuronidation pathway.
Slovenian: Gemfibrozil poveča AUC simvastatinske kisline za 1,9-krat, morda zaradi zaviranja glukuronidacijske poti.
English: If a patient has previously experienced a muscle disorder on a fibrate or a statin, treatment with a different member of the class should only be initiated with caution.
Slovenian: Če se je pri bolniku prej pojavila mišična bolezen med zdravljenjem s fibratom ali statinom, je treba zdravljenje z drugim predstavnikom tega razreda zdravil uvesti s previdnostjo.
English: In a clinical trial, myopathy was reported in 6% of patients receiving simvastatin 80 mg and amiodarone, versus 0.4% in patients on simvastatin 80 mg only.
Slovenian: V kliničnem preskušanju so o miopatiji poročali pri 6 % bolnikov, ki so prejemali simvastatin 80 mg in amiodaron, in pri 0,4 % bolnikov, ki so prejemali samo simvastatin 80 mg.
English: Fenofibrate is a mild to moderate inhibitor of CYP 2C9 and a weak inhibitor of CYP 2C19 and CYP 2A6.
Slovenian: Fenofibrat je blag do zmeren zaviralec CYP 2C9 in šibek zaviralec CYP 2C19 in CYP 2A6.
English: • cramps or painful, tender or weak muscles - these may be signs of muscle inflammation or breakdown, which can cause kidney damage or even death
Slovenian: • krči ali boleče, občutljive ali šibke mišice - to so lahko znaki vnetja ali razpadanja mišic, ki lahko povzroči poškodbe ledvic ali celo smrt,
English: As well as the medicines listed previously, tell your doctor or pharmacist if you are taking, have recently taken or might take any of the following medicines:
Slovenian: Kot pri zdravilih, naštetih zgoraj, obvestite zdravnika ali farmacevta tudi, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli od naslednjih zdravil:
English: Some evidence suggests that statins as a class raise blood glucose and in some patients, at high risk of future diabetes, may produce a level of hyperglycaemia where formal diabetes care is appropriate.
Slovenian: Nekateri podatki nakazujejo, da statini kot razred zdravil zvišajo raven glukoze v krvi, pri določenih bolnikih z visokim tveganjem za razvoj sladkorne bolezni pa lahko povzročijo hiperglikemijo, ki zahteva uradno obravnavo sladkorne bolezni.
English: The tablets are provided in carton boxes with blisters containing 10, 30 or 90 tablets.
Slovenian: Tablete so v kartonskih škatlah s pretisnimi omoti po 10, 30 ali 90 tablet.
English: Fenofibrate Acute toxicity studies have yielded no relevant information about specific toxicity of fenofibrate.
Slovenian: Fenofibrat V študijah akutne toksičnosti niso ugotovili pomembnih informacij o specifični toksičnosti fenofibrata.
English: Cholib is used in adults at high risk of problems like heart attack and stroke who have high blood levels of 2 types of fats (triglycerides and LDL cholesterol).
Slovenian: Zdravilo Cholib se uporablja pri odraslih bolnikih z velikim tveganjem za težave, kot sta srčni infarkt in možganska kap, ki imajo zvišane ravni dveh vrst maščob (trigliceridov in holesterola LDL).
English: The pharmacokinetics of single and multiple doses of simvastatin showed that no accumulation of medicinal product occurred after multiple dosing.
Slovenian: Farmakokinetika enkratnega in večkratnih odmerkov simvastatina kaže, da se po večkratnih odmerkih zdravilo ne akumulira.
English: In exceptional circumstances, where prolonged systemic fusidic acid is needed e.g. for the treatment of severe infections, the need for co-administration of Cholib and fusidic acid should only be considered on a case by case basis and under close medical supervision.
Slovenian: V izjemnih okoliščinah, kadar je potrebno daljše sistemsko zdravljenje s fusidno kislino, npr. za zdravljenje hujših okužb, se potreba po sočasnem dajanju zdravila Cholib in fusidne kisline ocenjuje od primera do primera, zdravljenje pa se izvaja pod strogim zdravniškim nadzorom.
English: Other statins and fibrates
Slovenian: Drugi statini in fibrati
English: • If while taking other medicines, you have had an allergic reaction or skin damage from sunlight or UV light (these medicines include other fibrates and an anti-inflammatory medicine called “ketoprofen”)
Slovenian: • če ste med jemanjem drugih zdravil imeli alergijsko reakcijo ali kožno reakcijo na sončno ali UV svetlobo (med ta zdravila spadajo drugi fibrati in protivnetno zdravilo, imenovano „ketoprofen“),
English: INR should be determined before starting Cholib and frequently enough during early therapy to ensure that no significant alteration of INR occurs.
Slovenian: Na začetku zdravljenja pa je treba vrednost INR določati dovolj pogosto, da se preprečijo pomembne spremembe vrednosti INR.
English: Creatine kinase measurement
Slovenian: Meritve kreatin-kinaze
English: Some cases of reversible paradoxical reduction of HDL-C have been reported during concomitant administration of fenofibrate and glitazones.
Slovenian: Poročali so o določenih primerih reverzibilnega paradoksalnega znižanja ravni HDL-holesterola pri sočasni uporabi fenofibrata in glitazonov.