FrancophonIA/ELRC3.0 huggingface dataset:
English: There is no relevant use of Relvar Ellipta in the paediatric population for the indication of COPD.
Croatian: Nije opravdana primjena lijeka Relvar Ellipta u pedijatrijskoj populaciji za indikaciju KOPB-a.
English: • weakening of the bones, leading to fractures
Croatian: • slabljenje kostiju koje izaziva prijelome • bol u trbuhu
English: You can also report side effects directly via the national reporting system listed in Appendix V .
Croatian: Nuspojave možete prijaviti izravno putem nacionalnog sustava za prijavu nuspojava: navedenog u Dodatku V.
English: Rinsing your mouth out with water immediately after using Relvar Ellipta may help stop this side effect developing.
Croatian: Ispiranje usta vodom odmah nakon primjene lijeka Relvar Ellipta može pomoći u sprječavanju pojave ove nuspojave.
English: There is no additional benefit of the 184/22 micrograms dose compared to the 92/22 micrograms dose and there is a potential increased risk of pneumonia and systemic corticosteroid-related adverse reactions (see sections 4.4 and 4.8).
Croatian: Nema dodatnih korisnih učinaka kod primjene doze od 184/22 mikrograma u odnosu na dozu od 92/22 mikrograma, ali postoji mogućnost povećanog rizika od pneumonije i nuspojava povezanih sa sistemskim djelovanjem kortikosteroida (vidjeti dijelove 4.4 i 4.8).
English: The medicine is now ready to be inhaled.
Croatian: Lijek je sada spreman za inhaliranje.
English: In HZA106837 all patients had at least one exacerbation that required treatment with oral corticosteroids in the year prior to visit 1.
Croatian: U ispitivanju HZA106837 svi su ispitanici imali barem jednu egzacerbaciju koja je zahtijevala liječenje peroralnim kortikosteroidima unutar godine dana prije 1. posjeta.
English: Each delivered dose contains approximately 25 mg of lactose (as monohydrate).
Croatian: Jedna primijenjena doza sadrži približno 25 mg laktoze (u obliku hidrata).
English: No dosage adjustment is necessary based on gender, weight or BMI.
Croatian: Nije potrebno prilagođavati dozu na temelju spola, tjelesne težine ili indeksa tjelesne mase.
English: Co-administration should be avoided unless the benefit outweighs the increased risk of systemic corticosteroid undesirable effects, in which case patients should be monitored for systemic corticosteroid undesirable effects.
Croatian: Istodobnu primjenu treba izbjegavati, osim kada korist nadmašuje povećani rizik od neželjenih sistemskih učinaka kortikosteroida, a u tom slučaju je bolesnike potrebno pratiti radi otkrivanja neželjenih sistemskih učinaka kortikosteroida.
English: The inhaler is a multi-component device composed of polypropylene, high density polyethylene, polyoxymethylene, polybutylene terephthalate, acrylonitrile butadiene styrene, polycarbonate and stainless steel.
Croatian: Inhalator je višedijelni uređaj koji se sastoji od polipropilena, polietilena visoke gustoće, polioksimetilena, polibutilen tereftalata, akrilonitril butadien stirena, polikarbonata i nehrđajućeg čelika.
English: For an elderly subject (aged 84 years) with low bodyweight (35 kg) vilanterol AUC (0-24) is predicted to be 35% higher than the population estimate (subject with COPD aged 60 years and bodyweight of 70 kg), whilst Cmax was unchanged.
Croatian: U starijeg ispitanika (u dobi od 84 godine) male tjelesne težine (35 kg) predviđeni AUC(0-24) vilanterola je 35% viši od procijenjene vrijednosti za populaciju (ispitanik s KOPB-om u dobi od 60 godina i tjelesnom težinom od 70 kg), dok Cmax ostaje nepromijenjen.
English: If you have severe asthma, your doctor may decide that you should use one inhalation of the higher strength inhaler (184 micrograms fluticasone furoate and 22 micrograms of vilanterol).
Croatian: Ako imate tešku astmu, liječnik će možda donijeti odluku da morate primjenjivati jednu inhalaciju jačeg inhalatora (184 mikrograma flutikazonfuroata i 22 mikrograma vilanterola).
English: Fluticasone furoate/vilanterol should be administered with caution in patients with pulmonary tuberculosis or in patients with chronic or untreated infections.
Croatian: Flutikazonfuroat/vilanterol treba primjenjivati uz oprez u bolesnika s tuberkulozom pluća ili u bolesnika s kroničnim ili neliječenim infekcijama.
English: INFORMATION IN BRAILLE relvar ellipta 92:22
Croatian: 16. PODACI NA BRAILLEOVOM PISMU relvar ellipta 92:22
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS TRAY LABEL
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI BLISTER ILI STRIP NALJEPNICA NA PODLOŠKU
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (Pharmacovigilance or risk minimisation) milestone being reached.
Croatian: • prilikom svake izmjene sustava za upravljanje rizikom, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik,
English: Systemic effects may occur with any inhaled corticosteroid, particularly at high doses prescribed for long periods.
Croatian: Svi inhalacijski kortikosteroidi mogu imati sistemske učinke, osobito ako se dugotrajno primjenjuju u velikim dozama.
English: There was no evidence for age (12-84) to affect the pharmacokinetics of fluticasone furoate and vilanterol in subjects with asthma.
Croatian: Nije dokazano da životna dob (12-84) utječe na farmakokinetiku flutikazonfuroata i vilanterola u ispitanika s astmom.
English: The oral bioavailability of both fluticasone furoate and vilanterol was low, on average 1.26% and <2%, respectively.
Croatian: Oralna bioraspoloživost flutikazonfuroata i vilanterola bila je niska, u prosjeku 1,26% odnosno <2%.
English: Your doctor may wish to monitor you carefully if you are taking any of these medicines as they may increase the side effects of Relvar Ellipta.
Croatian: Vaš liječnik će Vas možda htjeti pažljivo pratiti ako uzimate takve lijekove, jer oni mogu povećati nuspojave lijeka
English: It will only be effective as long as you are using it. Do not stop unless your doctor advises you to, even if you feel better.
Croatian: Nemojte prestati primjenjivati lijek, osim ako Vam to ne kaže liječnik, čak i ako se osjećate bolje.
English: If patients are inadequately controlled on Relvar Ellipta 92/22 micrograms, the dose can be increased to 184/22 micrograms, which may provide additional improvement in asthma control.
Croatian: Ako bolesnici nisu dobro kontrolirani lijekom Relvar Ellipta od 92/22 mikrograma, doza se može povećati na 184/22 mikrograma, što može dodatno poboljšati kontrolu astme.
English: What Relvar Ellipta looks like and contents of the pack The Ellipta device itself is a light grey inhaler with a yellow mouthpiece cover and a dose counter.
Croatian: Kako Relvar Ellipta izgleda i sadržaj pakiranja Sam uređaj Ellipta je svijetlosivi inhalator sa žutim poklopcem nastavka za usta i brojačem doza.
English: If symptoms arise in the period between doses, an inhaled, short-acting beta2-agonist should be used for immediate relief.
Croatian: Ako se simptomi pojave u razdoblju između primjene dviju doza, treba uzeti kratkodjelujući inhalacijski beta2-agonist za trenutno ublažavanje simptoma.
English: if you think the above applies to you, don't use Relvar Ellipta until you have checked with your doctor.
Croatian: • ako mislite da se gore navedeno odnosi na Vas, nemojte primjenjivati Relvar Ellipta dok se ne posavjetujete sa svojim liječnikom.
English: There is insufficient information on the excretion of fluticasone furoate or vilanterol trifenatate and/or metabolites in human milk.
Croatian: Nema dovoljno podataka o izlučivanju flutikazonfuroata ili vilanteroltrifenatata i/ili njihovih metabolita u majčino mlijeko.
English: The primary endpoint was all-cause mortality and a secondary endpoint was a composite of cardiovascular events (on-treatment cardiovascular death, myocardial infarction, stroke, unstable angina, or transient ischemic attack).
Croatian: Primarna mjera ishoda bila je smrt zbog bilo kojeg uzroka, dok su sekundarnu mjeru ishoda činili objedinjeni kardiovaskularni događaji (smrt tijekom liječenja zbog kardiovaskularnog uzroka, infarkt miokarda, moždani udar, nestabilna angina ili tranzitorna ishemijska ataka).
English: In vitro plasma protein binding in human plasma of fluticasone furoate and vilanterol was high, on average >99.6% and 93.9%, respectively.
Croatian: Stupanj vezivanja flutikazonfuroata i vilanterola za proteine u ljudskoj plazmi in vitro bio je visok, prosječno >99,6% za flutikazonfuroat odnosno 93,9% za vilanterol.
English: White powder in a light grey inhaler with a yellow mouthpiece cover and a dose counter.
Croatian: Bijeli prašak u svijetlosivom inhalatoru sa žutim poklopcem nastavka za usta i brojačem doza.
English: If you open and close the cover without inhaling the medicine, you will lose the dose.
Croatian: Ako otvorite i zatvorite poklopac inhalatora bez inhaliranja lijeka, izgubit ćete dozu.
English: Fluticasone furoate was not teratogenic in rats or rabbits, but delayed development in rats and caused abortion in rabbits at maternally toxic doses.
Croatian: Flutikazonfuroat nije imao teratogen učinak na štakore ni kuniće, ali je usporio razvoj u štakora i izazvao abortus u kunića pri primjeni doza toksičnih za skotne ženke.
English: What you need to know before you use Relvar Ellipta
Croatian: Što morate znati prije nego počnete primjenjivati Relvar Ellipta
English: An overdose of fluticasone furoate/vilanterol may produce signs and symptoms due to the individual component's actions, including those seen with overdose of other beta2-agonists and consistent with the known inhaled corticosteroid class effects (see section 4.4).
Croatian: Predoziranje flutikazonfuroatom/vilanterolom može izazvati znakove i simptome uslijed djelovanja pojedinih sastojaka lijeka, uključujući znakove i simptome zabilježene kod predoziranja drugim beta2-agonistima i sukladne poznatim učincima razreda inhalacijskih kortikosteroida (vidjeti dio 4.4).
English: HZC102970 and HZC102871 integrated
Croatian: HZC102970 i HZC102871 zajedno
English: When the inhaler is taken out of its tray, it will be in the ‘closed' position.
Croatian: Kada se inhalator izvadi iz podloška, nalazi se u 'zatvorenom' položaju.
English: Prior to randomization, subjects were required to discontinue previous COPD medications used at baseline, which included long-acting bronchodilators plus inhaled corticosteroids (28%), long-acting bronchodilators alone (11%) and inhaled corticosteroids alone (4%).
Croatian: Prije randomizacije ispitanici su morali prekinuti primjenu lijekova za KOPB koje su uzimali na početku ispitivanja, a koji su uključivali dugodjelujuće bronhodilatatore u kombinaciji s inhalacijskim kortikosteroidima (28%), samostalno primjenjivane dugodjelujuće bronhodilatatore (11%) i samostalno primjenjivane inhalacijske kortikosteroide (4%).
English: Caution is advised when co-administering with strong CYP 3A4 inhibitors (e.g. ketoconazole, ritonavir, cobicistat-containing products) as there is potential for increased systemic exposure to both fluticasone furoate and vilanterol.
Croatian: Preporučuje se oprez pri istodobnoj primjeni sa snažnim inhibitorima CYP 3A4 (npr. ketokonazolom, ritonavirom, lijekovima koji sadrže kobicistat) jer postoji mogućnost povećane sistemske izloženosti i flutikazonfuroatu i vilanterolu.
English: These were randomised controlled studies in patients with a clinical diagnosis of COPD.
Croatian: Navedena su ispitivanja bila randomizirana kontrolirana ispitivanja u bolesnika kojima je klinički dijagnosticiran KOPB.
English: All-cause mortality was: fluticasone furoate/vilanterol, 6.0%; placebo, 6.7%; fluticasone furoate, 6.1%; vilanterol, 6.4%.
Croatian: Smrt zbog bilo kojeg uzroka iznosila je 6,0% uz flutikazonfuroat/vilanterol, 6,7% uz placebo, 6,1% uz flutikazonfuroat te 6,4% uz vilanterol.
English: Interaction with P-glycoprotein inhibitors
Croatian: Interakcija s inhibitorima P-glikoproteina
English: Fluticasone furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity.
Croatian: Flutikazonfuroat je sintetički trifluorirani kortikosteroid s jakim protuupalnim djelovanjem.
English: When you first use the Ellipta inhaler you do not need to check that it is working properly, and you do not need to prepare it for use in any special way.
Croatian: Kada koristite Ellipta inhalator po prvi puta, ne morate provjeravati radi li ispravno niti ga morate posebno pripremati za uporabu.
English: If you become wheezy or breathless, or develop any other symptoms of an asthma attack, use your quick-acting inhaler (e.g. salbutamol), then seek medical advice.
Croatian: Ako dođe do piskanja pri disanju, ako ostanete bez zraka ili ako se pojave drugi simptomi napadaja astme, primijenite brzodjelujući inhalacijski lijek (npr. salbutamol), a zatim zatražite savjet liječnika.
English: Possible systemic effects include Cushing's syndrome, Cushingoid features, adrenal suppression, decrease in bone mineral density, growth retardation in children and adolescents, cataract and glaucoma and more rarely, a range of psychological or behavioural effects including psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression (particularly in children).
Croatian: Mogući sistemski učinci uključuju Cushingov sindrom, Cushingoidni izgled, supresiju nadbubrežne žlijezde, smanjenje mineralne gustoće kostiju, usporen rast u djece i adolescenata, kataraktu i glaukom te rjeđe niz psiholoških pojava ili promjena u ponašanju, uključujući psihomotoričku hiperaktivnost, poremećaje spavanja, anksioznost, depresiju ili agresivnost (osobito u djece).
English: Close the inhaler and rinse your mouth Slide the cover upwards as far as it will go to cover the mouthpiece.
Croatian: Zatvorite inhalator i isperite usta • Povucite poklopac prema gore koliko ide kako biste prekrili nastavak za usta.
English: Clinical pharmacology studies with a specific P-gp inhibitor and fluticasone furoate have not been conducted.
Croatian: Nisu provedena klinička farmakološka ispitivanja sa specifičnim inhibitorom P-gp-a i flutikazonfuroatom.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with Relvar Ellipta in one or more subsets of the paediatric population in asthma (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove odgodila je obvezu podnošenja rezultata ispitivanja lijeka Relvar Ellipta u jednoj ili više podskupina pedijatrijske populacije u astmi (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Relvar Ellipta contains two active substances: fluticasone furoate and vilanterol.
Croatian: Relvar Ellipta sadrži dvije djelatne tvari: flutikazonfuroat i vilanterol.
English: 1 inhaler of 14 doses 1 inhaler of 30 doses
Croatian: 1 inhalator s 14 doza 1 inhalator s 30 doza
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients Lactose monohydrate Magnesium stearate
Croatian: 6.1 Popis pomoćnih tvari laktoza hidrat magnezijev stearat
English: Fluticasone furoate or vilanterol has no or negligible influence on the ability to drive and use machines.
Croatian: Flutikazonfuroat ili vilanterol ne utječu ili zanemarivo utječu na sposobnost upravljanja vozilima i rada sa strojevima.
English: Take one long, steady, deep breath in.
Croatian: Udahnite jednom dugo i duboko.
English: In the asthma clinical development program a total of 7,034 patients were included in an integrated assessment of adverse reactions.
Croatian: U kliničkom razvojnom programu obuhvaćeno je ukupno 7034 bolesnika s astmom radi objedinjene procjene nuspojava.
English: Both studies had a 4 week run-in period during which all subjects received open-label salmeterol/FP 50/250 twice daily to standardise COPD pharmacotherapy and stabilise disease prior to randomisation to blinded study medication for 52 weeks.
Croatian: Oba su ispitivanja imala razdoblje prilagodbe od 4 tjedna, tijekom kojega su svi ispitanici otvoreno primali salmeterol/flutikazonpropionat od 50/250 mikrograma dvaput na dan kako bi se standardizirala farmakoterapija za KOPB i stabilizirala bolest prije randomizacije za primjenu lijeka u slijepom ispitivanju u trajanju od 52 tjedna.
English: Fluticasone furoate was not genotoxic in a standard battery of studies and was not carcinogenic in lifetime inhalation studies in rats or mice at exposures similar to those at the maximum recommended human dose, based on AUC.
Croatian: Flutikazonfuroat se nije pokazao genotoksičnim u standardnom skupu ispitivanja niti kancerogenim u ispitivanjima cjeloživotne inhalacije na štakorima ili miševima pri razinama izloženosti sličnima onima kod najveće preporučene doze u ljudi, utvrđene na temelju AUC-a.
English: Fluticasone furoate and vilanterol are both substrates of P-glycoprotein (P-gp).
Croatian: Flutikazonfuroat i vilanterol su oboje supstrati za P-glikoprotein (P-gp).
English: Elderly patients (> 65 years old)
Croatian: Stariji bolesnici (> 65 godina)
English: This helps to open the airways and makes it easier for air to get in and out of the lungs.
Croatian: Na taj se način otvaraju dišni putovi te se olakšava ulazak zraka u pluća i izlazak zraka iz pluća.
English: Prescribers should be aware that in patients with asthma, fluticasone furoate (FF) 100 micrograms once daily is approximately equivalent to fluticasone propionate (FP) 250 micrograms twice daily, while FF 200 micrograms once daily is approximately equivalent to FP 500 micrograms twice daily.
Croatian: Liječnici koji propisuju lijek moraju znati da je u bolesnika s astmom doza flutikazonfuroata (FF) od 100 mikrograma jedanput na dan približno ekvivalentna dozi flutikazonpropionata (FP) od 250 mikrograma dvaput na dan, dok je doza flutikazonfuroata od 200 mikrograma jedanput na dan približno ekvivalentna dozi flutikazonpropionata od 500 mikrograma dvaput na dan.
English: Both fluticasone furoate and vilanterol have a low association with red blood cells.
Croatian: I flutikazonfuroat i vilanterol se u maloj mjeri vezuju za crvene krvne stanice.
English: Don't open the inhaler until you are ready to inhale a dose of medicine.
Croatian: Nemojte otvarati inhalator dok ne budete spremni inhalirati dozu lijeka.
English: Don't use this medicine if you are pregnant unless your doctor tells you that you can.
Croatian: Nemojte primijeniti ovaj lijek ako ste trudni, osim ako
English: Fluticasone furoate and vilanterol represent two classes of medications (a synthetic corticosteroid and a selective, long-acting beta2-receptor agonist).
Croatian: Flutikazonfuroat i vilanterol predstavljaju dvije skupine lijekova (sintetički kortikosteroid i dugodjelujući selektivni agonist beta2-receptora).
English: Relvar Ellipta should not be used in conjunction with other long-acting beta2-adrenergic agonists or medicinal products containing longacting beta2-adrenergic agonists.
Croatian: Relvar Ellipta se ne smije koristiti u kombinaciji s drugim dugodjelujućim agonistima beta2-adrenergičkih receptora niti lijekovima koji sadrže dugodjelujuće beta2-adrenergičke agoniste.
English: Symptoms come and go and include shortness of breath, wheezing, chest tightness and cough.
Croatian: Simptomi dolaze i prolaze, a uključuju nedostatak zraka, piskanje pri disanju, stezanje u prsima i kašalj.
English: Elderly patients (>65 years)
Croatian: Stariji bolesnici (>65 godina)
English: Relvar Ellipta is indicated for the symptomatic treatment of adults with COPD with a FEV1<70% predicted normal (post-bronchodilator) with an exacerbation history despite regular bronchodilator therapy.
Croatian: Relvar Ellipta je indiciran za simptomatsko liječenje odraslih bolesnika s KOPB-om koji imaju FEV1 < 70% predviđene normalne vrijednosti (nakon primjene bronhodilatatora) i s egzacerbacijama bolesti unatoč redovitom liječenju bronhodilatatorima.
English: Adjusted mean change from baseline in trough FEV1 was also evaluated as a secondary endpoint.
Croatian: Prilagođena srednja vrijednost promjene najniže vrijednosti FEV1 od početne također je ocijenjena kao sekundarna mjera ishoda.
English: Pharmacotherapeutic group: Drugs for obstructive airways diseases, adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics ATC code: R03AK10.
Croatian: Farmakoterapijska skupina: Lijekovi za liječenje opstruktivnih bolesti dišnih puteva, adrenergici u kombinaciji s kortikosteroidima ili drugim lijekovima, osim antikolinergika, ATK oznaka: R03AK10.
English: The use of concurrent inhaled long-acting bronchodilators (beta2-agonist and anticholinergic), ipratropium/salbutamol combination products, oral beta2-agonists, and theophylline preparations were not allowed during the treatment period.
Croatian: Istodobna primjena dugodjelujućih inhalacijskih bronhodilatatora (beta2-agonista i antikolinergika), lijekova s kombinacijom ipratropija/salbutamola, peroralnih beta2-agonista i teofilina nije bila dopuštena tijekom liječenja.
English: Patients usually experience an improvement in lung function within 16-17 minutes of inhaling Relvar Ellipta.
Croatian: Bolesnici obično osjete poboljšanje plućne funkcije unutar 16-17 minuta nakon inhaliranja lijeka Relvar Ellipta.
English: The European Medicines Agency has waived the obligation to submit the results of studies with Relvar Ellipta in all subsets of the paediatric population in COPD (see section 4.2 for information on paediatric use).
Croatian: Europska agencija za lijekove izuzela je obvezu podnošenja rezultata ispitivanja lijeka Relvar Ellipta u svim podskupinama pedijatrijske populacije u KOPB-u (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Given this low oral bioavailability, systemic exposure for fluticasone furoate and vilanterol following inhaled administration is primarily due to absorption of the inhaled portion of the dose delivered to the lung.
Croatian: S obzirom na tu nisku bioraspoloživost, sistemska izloženost flutikazonfuroatu i vilanterolu nakon inhalacijske primjene prvenstveno je posljedica apsorpcije inhaliranog dijela doze lijeka koji se isporučuje u pluća.
English: The effective half-life for accumulation of vilanterol, as determined from inhalation administration of repeat doses of vilanterol 25 micrograms, is 16.0 hours in subjects with asthma and 21.3 hours in subjects with COPD.
Croatian: Efektivni poluvijek akumulacije vilanterola, utvrđen na temelju inhalacijske primjene ponovljenih doza vilanterola od 25 mikrograma, iznosi 16,0 sati u ispitanika s astmom odnosno 21,3 sata u ispitanika s KOPB-om.
English: Following oral administration, fluticasone furoate was eliminated in humans mainly by metabolism with metabolites being excreted almost exclusively in faeces, with <1% of the recovered radioactive dose eliminated in the urine.
Croatian: Nakon peroralne primjene, flutikazonfuroat se u ljudi uglavnom eliminirao metabolizmom, a metaboliti su se izlučivali gotovo isključivo u feces, pri čemu se <1% pronađene radioaktivne doze izlučilo u mokraću.
English: Asthma is a serious, long term lung disease where the muscles surrounding the smaller airways become tight (bronchoconstriction) and swollen and irritated (inflammation).
Croatian: Astma je ozbiljna i dugotrajna plućna bolest u kojoj dolazi do stezanja mišića koji okružuju manje dišne puteve (bronhokonstrikcija) te do oticanja i nadraženosti (upala) malih dišnih puteva.
English: The safety and efficacy of fluticasone furoate/vilanterol in children under the age of 12 years has not yet been established.
Croatian: Sigurnost i djelotvornost flutikazonfuroata/vilanterola u djece mlađe od 12 godina nisu još ustanovljene.
English: Subjects used salbutamol on an as-needed basis throughout the studies.
Croatian: Ispitanici su po potrebi uzimali salbutamol tijekom čitavog trajanja obaju ispitivanja.
English: The adjusted mean treatment difference of 22 mL (95% CI: -18, 63mL) between the groups was not statistically significant (p=0.282).
Croatian: Prilagođena srednja vrijednost terapijskih razlika od 22 ml (95% CI: -18, 63 ml) između skupina nije bila statistički značajna (p=0,282).
English: Relvar Ellipta has been shown to reduce flare-ups and symptoms of asthma.
Croatian: Pokazalo se da Relvar Ellipta smanjuje razbuktavanje i simptome astme.