FrancophonIA/ELRC3.0 huggingface dataset:
English: Although the frequency of reports of dizziness in placebo and tadalafil arms in clinical trials was similar, patients should be aware of how they react to CIALIS, before driving or using machines.
Croatian: Iako je u kliničkim ispitivanjima učestalost prijavljivanja omaglice bila podjednaka u skupinama koje su primale placebo odnosno tadalafil, bolesnici moraju biti svjesni kako reagiraju na CIALIS prije nego upravljaju vozilom ili rukuju strojevima.
English: Tadalafil (10 mg except for studies with angiotensin II receptor blockers and amlodipine in which a 20 mg dose was applied) had no clinically significant interaction with any of these classes.
Croatian: Tadalafil (10 mg, osim u ispitivanjima s blokatorima receptora angiotenzina II i amlodipinom, gdje je primijenjena doza od 20 mg) ni s jednom od navedenih skupina nije imao klinički značajne interakcije.
English: CIALIS, should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie's disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia).
Croatian: CIALIS treba primjenjivati uz oprez u bolesnika s anatomskim deformacijama penisa (poput angulacije, kavernozne fibroze ili Peyronijeve bolesti) i u bolesnika koji pate od nekih stanja koja mogu biti predispozicija za prijapizam (poput anemije srpastih stanica, multiplog mijeloma ili leukemije).
English: However, you have been given the dose of one 20mg tablet as your doctor has decided that the recommended dose of 10mg is too weak.
Croatian: propisana Vam je doza od jedne tablete od 20 mg jer je Vaš liječnik odlučio da preporučena doza od
English: - riociguat.
Croatian: - riocigvat.
English: Effects of other substances on tadalafil
Croatian: Učinci drugih lijekova na tadalafil
English: In patients who anticipate a frequent use of CIALIS (i.e., at least twice weekly) a once daily regimen with the lowest doses of CIALIS might be considered suitable, based on patient choice and the physician's judgement.
Croatian: U bolesnika koji očekuju učestalu primjenu lijeka CIALIS (tj. najmanje dvaput tjedno) možda će biti primjerena primjena najniže doze lijeka jedanput na dan, ovisno o želji bolesnika i prosudbi liječnika.
English: When initiating daily treatment with tadalafil, appropriate clinical considerations should be given to a possible dose adjustment of the antihypertensive therapy.
Croatian: Kada se započinje liječenje tadalafilom, treba napraviti odgovarajuću kliničku procjenu moguće prilagodba doze antihipertenziva.
English: The role of transporters (for example p-glycoprotein) in the disposition of tadalafil is not known.
Croatian: Nije poznata uloga prijenosnika (primjerice, p-glikoproteina) u raspoloživosti tadalafila.
English: One of these studies assessed improvements in erectile dysfunction and signs and symptoms of benign prostatic hyperplasia in patients with both conditions.
Croatian: U jednom od tih ispitivanja procijenjeno je poboljšanje erektilne disfunkcije i ublažavanje znakova i simptoma benigne hiperplazije prostate u bolesnika koji su bolovali od obje bolesti.
English: Warnings and precautions Talk to your doctor before taking CIALIS.
Croatian: Obratite se svom liječniku prije nego uzmete CIALIS.
English: How to take CIALIS
Croatian: Kako uzimati CIALIS
English: Based on the results of a clinical study in which 150 subjects receiving daily doses of tadalafil 20 mg for 7 days and 0.4 mg sublingual nitroglycerin at various times, this interaction lasted for more than 24 hours and was no longer detectable when 48 hours had elapsed after the last tadalafil dose.
Croatian: Na temelju rezultata iz kliničkog ispitivanja u kojem je 150 ispitanika primalo dozu od 20 mg tadalafila na dan tijekom 7 dana i dozu od 0,4 mg nitroglicerina primijenjena sublingvalno u različito doba, ta je interakcija trajala dulje od 24 sata, a nije više bila mjerljiva 48 sati nakon primjene posljednje doze tadalafila.
English: Preclinical studies showed an additive systemic blood pressure lowering effect when PDE5 inhibitors were combined with riociguat.
Croatian: Pretklinička ispitivanja pokazala su aditivan učinak na sniženje sistemskog krvnog tlaka kada su se inhibitori PDE5 primjenjivali u kombinaciji s riocigvatom.
English: When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum.
Croatian: Kad seksualna stimulacija izazove lokalno otpuštanje dušikova oksida, tadalafil inhibira PDE5 i tako dovodi do povišenih koncentracija cGMP-a u šupljikavom tijelu.
English: The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced.
Croatian: Posljedično opuštanje krvni žila povećava perfuziju krvi, što bi mogao biti mehanizam kojim se ublažavaju simptomi benigne hiperplazije prostate.
English: Effects of tadalafil on other medicinal products
Croatian: Učinci tadalafila na druge lijekove
English: CIALIS 5 mg is used to treat adult men with: - erectile dysfunction.
Croatian: CIALIS 5 mg tablete primjenjuju se za liječenje odraslih muškaraca koji imaju: - erektilnu disfunkciju.
English: In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried.
Croatian: U bolesnika u kojih tadalafil u dozi od 10 mg ne izazove odgovarajući učinak može se pokušati s dozom od 20 mg.
English: Tadalafil is also > 10,000-fold more potent for PDE5 than for PDE7 through PDE10.
Croatian: Tadalafil također djeluje > 10 000 puta jače na PDE5 nego na enzime PDE7 do PDE10.
English: - priapsim, a prolonged and possibly painful erection after taking CIALIS (frequency rare).
Croatian: - prijapizam, dugotrajna i potencijalno bolna erekcija nakon uzimanja lijeka CIALIS (rijetka učestalost).
English: With regard to those interaction studies where only the 10 mg tadalafil dose was used, clinically relevant interactions at higher doses cannot be completely ruled out.
Croatian: U ispitivanjima interakcija u kojima je tadalafil primijenjen samo u dozi od 10 mg ne mogu se u potpunosti isključiti klinički značajne interakcije pri većim dozama.
English: Following sexual stimulation CIALIS works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis.
Croatian: Nakon seksualne stimulacije CIALIS pridonosi opuštanju krvnih žila u penisu i tako omogućuje dotok krvi u penis.
English: CIALIS has been shown to significantly improve the ability of obtaining a hard erect penis suitable for sexual activity.
Croatian: Pokazalo se da CIALIS značajno poboljšava sposobnost postizanja i održavanja ukrućenosti dostatne za uspješnu seksualnu aktivnost.
English: Antidiabetic medicinal products Specific interaction studies with antidiabetic medicinal products were not conducted.
Croatian: Antidijabetici Nisu provedena posebna ispitivanja interakcija s antidijabeticima.
English: 5- alpha reductase inhibitors
Croatian: Inhibitori 5-alfa reduktaze
English: Patients with diabetes
Croatian: Bolesnici sa šećernom bolešću
English: The most commonly reported adverse reactions in patients taking CIALIS for the treatment of erectile dysfunction or benign prostatic hyperplasia were headache, dyspepsia, back pain and myalgia, in which the incidences increase with increasing dose of CIALIS.
Croatian: Najčešće prijavljena nuspojava u bolesnika koji uzimaju CIALIS za liječenje erektilne disfunkcije ili benigne hiperplazije prostate bile su glavobolja, dispepsija, bolovi u leđima i mialgija, a njihova je incidencija rasla s povećanjem doze lijeka CIALIS.
English: The randomised, double-blind, placebo-controlled, parallel, 3-arm study of tadalafil was conducted in 331 boys aged 7-14 years with DMD receiving concurrent corticosteroid therapy.
Croatian: To randomizirano, dvostruko slijepo, placebom kontrolirano ispitivanje tadalafila s tri paralelne skupine provedeno je u 331 dječaka s DMD-om u dobi od 7 do 14 godina koji su istodobno primali terapiju kortikosteroidima.
English: Treatment of the signs and symptoms of benign prostatic hyperplasia in adult males.
Croatian: Liječenje znakova i simptoma benigne hiperplazije prostate u odraslih muškaraca.
English: CIALIS is not intended for use by women.
Croatian: CIALIS nije namijenjen za primjenu u žena.
English: Tadalafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by acetyl salicylic acid.
Croatian: Tadalafil (10 mg i 20 mg) nije potencirao produljenje vremena krvarenja uzrokovano acetilsalicilatnom kiselinom.
English: Benign prostatic hyperplasia
Croatian: Benigna hiperplazija prostate
English: The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle of the prostate, the bladder and their vascular supply.
Croatian: Učinak inhibicije PDE5 na koncentracije cGMP-a u šupljikavom tijelu također je primijećen u glatkom mišićju prostate, mjehura i krvnih žila koje ih opskrbljuju.
English: Tadalafil is > 10,000-fold more potent for PDE5 than for PDE1, PDE2, and PDE4, enzymes which are found in the heart, brain, blood vessels, liver, and other organs.
Croatian: Tadalafil djeluje > 10 000 puta jače na PDE5 nego na PDE1, PDE2 i PDE4, enzime koji se nalaze u srcu, mozgu, krvnim žilama, jetri i drugim organima.
English: Studies have confirmed that tadalafil does not inhibit or induce CYP450 isoforms, including CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 and CYP2C19.
Croatian: Ispitivanja su potvrdila da tadalafil ne inhibira niti inducira izoforme CYP450, uključujući CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 i CYP2C19.
English: A CYP3A4 inducer, rifampicin, reduced tadalafil AUC by 88 %, relative to the AUC values for tadalafil alone (10 mg).
Croatian: Rifampicin, induktor CYP3A4, smanjio je AUC tadalafila za 88 % u odnosu na vrijednost AUC-a kod primjene samog tadalafila (10 mg).
English: The maintenance of the effect was evaluated in an open-label extension to one of the studies, which showed that the improvement in total international prostate symptom score seen at 12 weeks was maintained for up to 1 additional year of treatment with CIALIS 5mg.
Croatian: Održavanje učinka procijenjeno je u otvorenom produžetku jednog ispitivanja u kojem je poboljšanje ukupnog rezultata na Međunarodnoj ljestvici simptoma prostatizma primijećeno u 12. tjednu održano tijekom jedne dodatne godine liječenja lijekom CIALIS u dozi od 5 mg.
English: Although specific interactions have not been studied, other protease inhibitors, such as saquinavir, and other CYP3A4 inhibitors, such as erythromycin, clarithromycin, itraconazole and grapefruit juice should be co-administered with caution as they would be expected to increase plasma concentrations of tadalafil (see section 4.4).
Croatian: Iako specifične interakcije nisu ispitane, druge inhibitore proteaze, poput sakvinavira, i druge inhibitore CYP3A4, poput eritromicina, klaritromicina, itrakonazola i soka od grejpa, treba primjenjivati uz oprez jer se očekuje da bi ti lijekovi mogli dovesti do povećanja koncentracije tadalafila u plazmi (vidjeti dio 4.4).
English: - removal of all or part of the prostate gland in which nerves of the prostate are cut (radical non nerve-sparing prostatectomy).
Croatian: - kojima je djelomično ili u cijelosti uklonjena prostata i pritom su prerezani živci prostate (radikalna prostatektomija pri kojoj nisu očuvani živci).
English: Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).
Croatian: Tadalafil je selektivni, reverzibilni inhibitor fosfodiesteraze tipa 5 (PDE5) specifične za ciklički gvanozinfosfat (cGMP).
English: A. MANUFACTUR ER(S) RESPONSIBLE FOR BATCH RELEASE
Croatian: PRILOG II. A. PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET
English: These vascular effects may be complemented by inhibition of bladder afferent nerve activity and smooth muscle relaxation of the prostate and bladder.
Croatian: Navedene krvožilne učinke može pratiti inhibicija aktivnosti aferentnog živca u mjehuru i opuštanje glatkih mišića prostate i mjehura.
English: The maximum dose frequency is once per day.
Croatian: Najčešća učestalost doziranja smije biti jednom na dan.
English: Deutschland Lilly Deutschland GmbH
Croatian: Lilly Deutschland GmbH Tel.
English: This is when the prostate gland gets bigger with age.
Croatian: To je stanje u kojem se žlijezda prostata povećava s dobi.
English: CIALIS improves blood flow to, and relaxes the muscles of, the prostate and bladder which may reduce symptoms of benign prostatic hyperplasia.
Croatian: CIALIS poboljšava dotok krvi i opušta mišiće prostate i mjehura, čime se mogu ublažiti simptomi benigne hiperplazije prostate.
English: If you experience any of the following side effects stop using the medicine and seek medical help immediately: - allergic reactions including rashes (frequency uncommon).
Croatian: Ako se pojavi bilo koja od sljedećih nuspojava, prestanite uzimati lijek i odmah zatražite pomoć liječnika: - alergijske reakcije, uključujući osipe (manje česta učestalost).
English: CIALIS is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure (see section 4.4).
Croatian: CIALIS je kontraindiciran u bolesnika koji su izgubili vid na jednom oku zbog nearterijske prednje ishemijske optičke neuropatije (NAION, engl. non-arteritic anterior ischaemic optic neuropathy), bez obzira na to je li ta epizoda povezana s prethodnim izlaganjem inhibitorima PDE5 (vidjeti dio 4.4).
English: Check carefully how you react to the tablets before driving or using machines.
Croatian: Prije vožnje ili rukovanja strojevima dobro provjerite kako reagirate na tablete.
English: Concomitant use of riociguat with PDE5 inhibitors, including tadalafil, is contraindicated (see section 4.3).
Croatian: Istodobna primjena riocigvata s inhibitorima PDE5, uključujući tadalafil, je kontraindicirana (vidjeti dio 4.3).
English: In clinical trials with tadalafil taken on demand for the treatment of erectile dysfunction, diarrhoea was reported more frequently in patients over 65 years of age.
Croatian: U kliničkim ispitivanjima primjene tadalafila po potrebi za liječenje erektilne disfunkcije, proljev je prijavljen češće u bolesnika starijih od 65 godina.
English: However, appropriate clinical advice should be given to patients regarding a possible decrease in blood pressure when they are treated with antihypertensive medicinal products.
Croatian: Međutim, bolesnicima treba dati odgovarajuće kliničke preporuke o mogućem sniženju krvnog tlaka kod liječenja antihipertenzivima.
English: In order for tadalafil to be effective, sexual stimulation is required.
Croatian: Za djelotvornost tadalafila potrebna je seksualna stimulacija.
English: In patients receiving concomitant antihypertensive medicinal products, tadalafil may induce a blood pressure decrease.
Croatian: U bolesnika koji istodobno primaju antihipertenzive tadalafil može izazvati sniženje krvnog tlaka.
English: Before taking the tablets, tell your doctor if you have: - sickle cell anaemia (an abnormality of red blood cells).
Croatian: Prije uzimanja tableta, obavijestite svog liječnika ako imate: - anemiju srpastih stanica (poremećaj crvenih krvnih stanica)
English: Do not use this medicine after the expiry date which is stated on the carton and blister after ‘EXP'.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i blisteru iza oznake „Rok valjanosti" ili „EXP“.
English: It is not known if CIALIS is effective in patients who have undergone pelvic surgery or radical non-nervesparing prostatectomy.
Croatian: Nije poznato je li CIALIS djelotvoran u bolesnika koji su bili podvrgnuti kirurškom zahvatu u zdjelici ili radikalnoj prostatektomiji pri kojoj nisu očuvani živci.
English: When tadalafil was administered with lower doses of alcohol (0.6 g/kg), hypotension was not observed and dizziness occurred with similar frequency to alcohol alone.
Croatian: Kad je tadalafil primijenjen s nižim dozama alkohola (0,6 g/kg) nije primijećena hipotenzija, a omaglica se javljala s jednakom učestalošću kao i kod primjene alkohola samostalno.
English: Urticaria, Stevens-Johnson syndrome2, Exfoliative dermatitis2, Hyperhydrosis (sweating)
Croatian: Stevens-Johnsonov sindrom2, eksfolijativni dermatitis2, hiperhidroza (znojenje)
English: The evaluation of erectile dysfunction should include a determination of potential underlying causes and the identification of appropriate treatment following an appropriate medical assessment.
Croatian: Procjena erektilne disfunkcije treba uključivati utvrđivanje potencijalnih osnovnih uzroka te određivanje primjerene terapije nakon odgovarajuće liječničke procjene.
English: Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.
Croatian: Tadalafil od 10 i 20 mg namijenjen je za primjenu prije očekivane seksualne aktivnosti i ne preporučuje se kontinuirana svakodnevna primjena.
English: (2) Postmarketing surveillance reported adverse reactions not observed in placebo-controlled clinical trials.
Croatian: (2) Nuspojave prijavljene tijekom praćenja nakon stavljanja lijeka u promet, a koje nisu primijećene u placebom kontroliranim kliničkim ispitivanjima.
English: Prior to initiating treatment with tadalafil for benign prostatic hyperplasia patients should be examined to rule out the presence of carcinoma of the prostate and carefully assessed for cardiovascular conditions (see section 4.3).
Croatian: Prije početka liječenja benigne hiperplazije prostate tadalafilom bolesnike treba pregledati kako bi se isključilo postojanje karcinoma prostate i provesti podrobnu procjenu kako bi se utvrdilo postojanje kardiovaskularnih bolesti (vidjeti dio 4.3).
English: If you take more than you should, tell your doctor.
Croatian: Ako ste uzeli više tableta nego što ste trebali, obratite se liječniku.
English: Erectile dysfunction in adult men
Croatian: Doziranje Erektilna disfunkcija u odraslih muškaraca
English: CYP1A2 substrates (e.g. theophylline)
Croatian: Supstrati CYP1A2 (npr. teofilin)
English: Pharmacotherapeutic group: Urologicals, Drugs used in erectile dysfunction, ATC Code: G04BE08.
Croatian: 5.1 Farmakodinamička svojstva Farmakoterapijska skupina: Pripravci koji djeluju na mokraćni sustav; lijekovi koji se primjenjuju kod erektilne disfunkcije, ATK oznaka: G04BE08.
English: Patients who are unable to tolerate tadalafil 5 mg for the treatment of benign prostatic hyperplasia should consider an alternative therapy as the efficacy of tadalafil 2.5mg for the treatment of benign prostatic hyperplasia has not been demonstrated.
Croatian: U bolesnika koji ne podnose dozu tadalafila od 5 mg za liječenje benigne hiperplazije prostate treba razmotriti alternativno liječenje jer nije dokazana djelotvornost doze tadalafila od 2,5 mg u liječenju benigne hiperplazije prostate.
English: Serious cardiovascular events, including myocardial infarction, sudden cardiac death, unstable angina pectoris, ventricular arrhythmia, stroke, transient ischemic attacks, chest pain, palpitations and tachycardia, have been reported either post marketing and/or in clinical trials.
Croatian: Ozbiljni kardiovaskularni događaji, uključujući infarkt miokarda, iznenadnu srčanu smrt, nestabilnu anginu pektoris, ventrikularnu aritmiju, moždani udar, tranzitornu ishemijsku ataku, bol u prsištu, palpitacije i tahikardiju prijavljeni su ili nakon stavljanja lijeka u promet i/ili u kliničkim ispitivanjima.
English: If the effect of this dose is too weak your doctor may increase the dose to 20 mg. CIALIS tablets are for oral use.
Croatian: Ako je učinak te doze preslab, liječnik može povećati dozu na 20 mg.
English: Tadalafil (20 mg) did not augment the mean blood pressure decrease produced by alcohol (0.7 g/kg or approximately 180 ml of 40 % alcohol [vodka] in an 80-kg male) but in some subjects, postural dizziness and orthostatic hypotension were observed.
Croatian: Tadalafil (20 mg) nije povećao prosječno sniženje krvnog tlaka izazvano alkoholom (0,7 g/kg ili približno 180 ml 40% tnog alkohola [votka] u muškarca tjelesne težine 80 kg), no u nekih su ispitanika zabilježene posturalna omaglica i ortostatska hipotenzija.
English: Major classes of antihypertensive medicinal products were studied, including calcium channel blockers (amlodipine), angiotensin converting enzyme (ACE) inhibitors (enalapril), beta-adrenergic receptor blockers (metoprolol), thiazide diuretics (bendrofluazide), and angiotensin II receptor blockers (various types and doses, alone or in combination with thiazides, calcium channel blockers, beta-blockers, and/or alpha-blockers).
Croatian: Ispitivane su glavne skupine antihipertenziva, uključujući blokatore kalcijevih kanala (amlodipin), inhibitore angiotenzin konvertirajućeg enzima (ACE) (enalapril), blokatore betaadrenergičkih receptora (metoprolol), tiazidske diuretike (bendrofluazid) i blokatore receptora angiotenzina II (različite vrste i doze, samostalno ili u kombinaciji s tiazidima, blokatorima kalcijevih kanala, beta-blokatorima i/ili alfa-blokatorima).
English: What you need to know before you take CIALIS Do not take CIALIS if you: - are allergic to tadalafil or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte uzimati CIALIS: - ako ste alergični na tadalafil ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: It is important to note that CIALIS does not work if there is no sexual stimulation.
Croatian: Važno je napomenuti da CIALIS ne djeluje ako izostane seksualna stimulacija.
English: Tadalafil administered to healthy subjects produced no significant difference compared to placebo in supine systolic and diastolic blood pressure (mean maximal decrease of 1.6/0.8 mm Hg, respectively), in standing systolic and diastolic blood pressure (mean maximal decrease of 0.2/4.6 mm Hg, respectively), and no significant change in heart rate.
Croatian: Tadalafil primijenjen u zdravih ispitanika nije u odnosu na placebo doveo do značajne razlike u vrijednostima sistoličkog i dijastoličkog krvnog tlaka u ležećem položaju (prosječno maksimalno sniženje za 1,6 odnosno 0,8 mmHg), vrijednostima sistoličkog i dijastoličkog krvnog tlaka u stojećem položaju (prosječno maksimalno sniženje za 0,2 odnosno 4,6 mmHg) kao ni do značajne promjene srčanog ritma.
English: In two of these studies decreases were observed in sperm count and concentration related to tadalafil treatment of unlikely clinical relevance.
Croatian: U dva od tih ispitivanja opaženo je smanjenje broja i koncentracije spermatozoida povezano s liječenjem tadalafilom, ali nije vjerojatno da bi to moglo imati klinički značaj.
English: In a study to assess the effects of tadalafil on vision, no impairment of colour discrimination (blue/green) was detected using the Farnsworth-Munsell 100-hue test.
Croatian: U ispitivanju u kojemu su se ocjenjivali učinci tadalafila na vid primjenom Farnsworth-Munsellovog testa 100 nijansi nije otkriven poremećaj razlikovanja boja (plava/zelena).
English: Analyses of observational data suggest an increased risk of acute NAION in men with erectile dysfunction following exposure to tadalafil or other PDE5 inhibitors.
Croatian: Analize opservacijskih podataka ukazuju na povećan rizik od akutne nearterijske prednje ishemijske optičke neuropatije u muškaraca s erektilnom disfunkcijom nakon izlaganja tadalafilu ili drugim inhibitorima PDE5.
English: In patients who are taking alpha1 blockers, concomitant administration of CIALIS may lead to symptomatic hypotension in some patients (see section 4.5).
Croatian: U bolesnika koji uzimaju blokatore alfa1-receptora istodobna primjena lijeka CIALIS može u nekim slučajevima dovesti do simptomatske hipotenzije (vidjeti dio 4.5).
English: - are taking riociguat.
Croatian: - ako uzimate riocigvat.