FrancophonIA/ELRC3.0 huggingface dataset:
English: Pathological gambling, increased libido, hypersexuality, compulsive spending or buying, binge eating and compulsive eating can occur in patients treated with dopamine agonists and/or other dopaminergic treatments.
Croatian: Kod bolesnika liječenih agonistima dopamina i/ili drugim dopaminergičkim lijekovima mogu se pojaviti patološko kockanje, povećan libido, hiperseksualnost, kompulzivno trošenje ili kupovanje, prejedanje i kompulzivno jedenje.
English: Cellulose, microcrystalline Tartaric acid
Croatian: 6.1 Popis pomoćnih tvari celuloza, mikrokristalična tartaratna kiselina kukuruzni škrob škrob, prethodno geliran kukuruzni talk stearatna kiselina
English: Musculoskeletal and connective tissue disorders Common: musculoskeletal pain (6.7% vs. 2.6%), neck pain (2.7% vs. 0%), arthritis (1.3% vs.0.7%) Renal and urinary disorders
Croatian: Često: mišićno-koštana bol (6,7% naspram 2,6%), bol u vratu (2,7% naspram 0%), artritis (1,3%
English: Uncommon: myocardial infarction (0.7% vs. 0%) Respiratory, thoracic and mediastinal disorders Common: rhinitis (3.4% vs. 0.7%)
Croatian: Često: angina pektoris (1,3% naspram 0%); Manje često: infarkt miokarda (0,7% naspram 0%) Poremećaji dišnog sustava, prsišta i sredoprsja
English: 4.7 Effects on ability to drive and use machines
Croatian: 4.7 Utjecaj na sposobnost upravljanja vozilima i rada sa strojevima Nisu provedene studije utjecaja na sposobnost upravljanja vozilima i rada sa strojevima.
English: Very common: headache (14.1% vs. 11.9%) Uncommon: cerebrovascular accident (0.7% vs. 0%)
Croatian: Vrlo često: glavobolja (14,1% naspram 11,9%)
English: Mylan Pharmaceuticals, S.L Tel: + 34 900 102 712
Croatian: Česká republika Mylan Pharmaceuticals s.r.o. Tel: + 420 222 004 400
English: • Common (may affect up to 1 in 10 people)
Croatian: • Često (mogu se javiti u 1 na 10 osoba)
English: Caution should be exercised when rasagiline is administered to a breast-feeding mother.
Croatian: Nužan je oprez kod primjene razagilina u dojilja.
English: Tel: + 386 1 236 31 85
Croatian: GSP Proizvodi d.o.o. Tel: +386 1 236 31 85
English: C-labelled rasagiline is approximately 60 to
Croatian: Vezanje za proteine plazme nakon pojedinačne oralne doze 14C-obilježenog razagilina je približno 60 do
English: Common: flatulence (1.3% vs.0%)
Croatian: Često: leukopenija (1,3% naspram 0%)
English: • headedness (orthostatic hypotension)
Croatian: (ortostatska hipotenzija)
English: How to take Rasagiline Mylan 4.
Croatian: Kako uzimati Rasagiline Mylan 4. Moguće nuspojave
English: • Uncommon (may affect up to 1 in 100 people)
Croatian: • Manje često (mogu se javiti u 1 na 100 osoba)
English: OTHER
Croatian: DODATAK
English: Rasagiline Mylan
Croatian: Što Rasagiline Mylan sadrži
English: • blistering rash (vesiculobullous rash)
Croatian: • upala zglobova (artritis)
English: Common: rash (1.1% vs. 0.3%)
Croatian: Često: rinitis (3,4% naspram 0,7%)
English: Common: urinary urgency (1.3% vs. 0.7%).
Croatian: Poremećaji bubrega i mokraćnog sustava Često: urgencija mokrenja (1,3% naspram 0,7%).
English: Deutschland Mylan dura GmbH
Croatian: V.J. Salomone Pharma Ltd
English: Similar reports of ICDs have also been received post-marketing with rasagiline.
Croatian: U postmarketinškom razdoblju su zaprimljene slične prijave poremećaja kontrole impulsa sa razagilinom.
English: Synthon s.r.o Brněnská 32/čp.
Croatian: Synthon s.r.o, Brněnská 32/čp. 597 678 01 Blansko Češka Republika
English: Salomone Pharma Ltd Tel: + 356 21 22 01 74
Croatian: Mylan Hrvatska d.o.o. Tel: +385 1 23 50 599
English: Investigations
Croatian: U ispitivanju
English: • joint inflammation (arthritis)
Croatian: • bol u zglobovima (artralgija)
English: Date of first authorisation: April 2015
Croatian: Datum prvog odobrenja: Travanj 2015
English: • At the request of the European Medicines Agency;
Croatian: • Na zahtjev Europske agencije za lijekove
English: Turn over to continue…
Croatian: Okrenuti za nastavak…
English: Always take Ristempa exactly as your doctor has told you.
Croatian: Uvijek primijenite Ristempu točno onako kako Vam je rekao liječnik.
English: If you use more Ristempa than you should
Croatian: Ako primijenite više Ristempe nego što biste trebali
English: Currently available data are described in sections 4.8, 5.1 and 5.2 but no recommendation on a posology can be made
Croatian: Trenutno dostupni podaci opisani su u dijelovima 4.8, 5.1. i 5.2, međutim nije moguće dati preporuku o doziranju.
English: Check the appearance of Ristempa.
Croatian: Provjerite izgled Ristempe.
English: • Outer area of upper arm (only if someone else is giving you the injection).
Croatian: • Vanjsko područje nadlaktice (samo ako vam netko drugi daje injekciju).
English: What Ristempa is and what it is used for
Croatian: Što je Ristempa i za što se koristi
English: Before you inject Ristempa you must do the following:
Croatian: Prije injiciranja Ristempe morate učiniti sljedeće:
English: Before you use a Ristempa pre-filled syringe with automatic needle guard, read this important information:
Croatian: Prije korištenja Ristempa napunjene štrcaljke s automatskim štitnikom za iglu, pročitajte ove važne informacije:
English: For more information, see section 5.1
Croatian: Za više informacija vidjeti dio 5.1.
English: Other medicines and Ristempa
Croatian: Drugi lijekovi i Ristempa
English: Do not warm Ristempa in any other way (for example, do not warm it in a microwave or in hot water).
Croatian: Ne zagrijavajte Ristempu ni na bilo koji drugi način (primjerice, u mikrovalnoj pećnici ili u vrućoj vodi).
English: 9/l or greater have been observed in less than 1% of patients receiving Ristempa.
Croatian: 9/l ili više primijećen je u manje od 1% bolesnika koji su primali Ristempu.
English: How do you, or the person injecting you, use Ristempa pre-filled syringe?
Croatian: Kako ćete Vi ili osoba koja Vam daje injekciju koristiti Ristempa napunjenu štrcaljku?
English: Do not shake Ristempa vigorously as this may affect its activity.
Croatian: Ne tresite snažno Ristempu jer to može utjecati na njezinu aktivnost.
English: Ristempa has not been tested in pregnant women.
Croatian: Ristempa nije ispitivana u trudnica.
English: The safety and efficacy of Ristempa in children has not yet been established.
Croatian: Sigurnost i djelotvornost Ristempe u djece nisu još ustanovljene.
English: RELEASE your thumb.
Croatian: OTPUSTITE palac.
English: Long term outcome was not studied (see section 4.4).
Croatian: Dugoročni ishod nije ispitivan (vidjeti poglavlje 4.4).
English: Ristempa is for use in adults aged 18 and over.
Croatian: Ristempa se primjenjuje u odraslih osoba starijih od 18 godina.
English: If you forget to inject Ristempa
Croatian: Ako ste zaboravili injicirati Ristempu
English: Read other side first
Croatian: Strana 2 Prvo pročitajte drugu stranu
English: See section “Description of selected adverse reactions” below.
Croatian: “Opis odabranih nuspojava“ ispod.
English: If you become pregnant during Ristempa treatment, please inform your doctor.
Croatian: Ukoliko zatrudnite tijekom primjene Ristempe, molimo obavijestite liječnika.
English: The potency of this product should not be compared to the potency of another pegylated or nonpegylated protein of the same therapeutic class.
Croatian: Potentnost ovog lijeka ne smije se uspoređivati s potentnošću drugih pegiliranih ili nepegiliranih proteina iste terapijske skupine.
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from Ristempa therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Croatian: Nužno je odlučiti da li prekinuti dojenje ili prekinuti liječenje/suzdržati se od liječenja lijekom Ristempa uzimajući u obzir korist dojenja za dijete i korist liječenja za ženu.
English: Talk to your doctor, pharmacist or nurse before using Ristempa:
Croatian: Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije primjene Ristempe:
English: Accidental exposure to freezing temperatures for a single period of less than 24 hours does not adversely affect the stability of Ristempa.
Croatian: Slučajno jednokratno izlaganje temperaturama zamrzavanja u razdoblju kraćem od 24 sata ne utječe nepovoljno na stabilnost Ristempe.
English: Side 1
Croatian: Strana 1
English: • if you are allergic to pegfilgrastim, filgrastim, E. coli derived proteins, or any of the other ingredients of this medicine.
Croatian: • ako ste alergični na pegfilgrastim, filgrastim, proteine dobivene iz E. coli ili neki drugi sastojak ovog lijeka.
English: Do not try to warm the syringe by using a heat source such as hot water or microwave.
Croatian: Ne pokušavajte ugrijati štrcaljku korištenjem izvora topline kao što su vruća voda ili
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached.
Croatian: • Uoči svake izmjene sustava upravljanja rizicima, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik, odnosno kada je omjer korist/rizik rezultat ostvarenja nekog važnog cilja (u smislu farmakovigilancije ili smanjenja rizika).
English: The frequency category was estimated from a statistical calculation based upon 1576 patients receiving Ristempa in nine randomized clinical trials.
Croatian: Kategorija učestalosti je procijenjena statističkim izračunom na temelju 1576 bolesnika koji su Ristempu primali u devet randomiziranih kliničkih ispitivanja.
English: What should I do before I give myself a subcutaneous injection of Ristempa?
Croatian: Što trebam učiniti prije samoprimjene potkožne injekcije Ristempe?
English: Local representative contact details are provided in section 6 of this leaflet.
Croatian: Podatke o kontaktu lokalnog predstavnika nalaze se u dijelu 6 ove upute.
English: What Ristempa is and what it is used for What you need to know before you use Ristempa
Croatian: Što je Ristempa i za što se koristi Što morate znati prije nego počnete primjenjivati Ristempu
English: Specific interaction or metabolism studies have not been performed, however, clinical trials have not indicated an interaction of Ristempa with any other medicinal products.
Croatian: Nisu provedena specifična ispitivanja interakcija ili metabolizma, no klinička ispitivanja nisu upućivala na interakciju Ristempe s bilo kojim drugim lijekovima.
English: Ristempa left at room temperature for more than 72 hours should be discarded.
Croatian: Ristempa ostavljena na sobnoj temperaturi dulje od 72 sata se mora ukloniti.
English: • Ristempa is given as an injection into the tissue just under the skin (subcutaneous injection).
Croatian: • Ristempa se daje u obliku injekcije u tkivo odmah ispod kože (potkožna injekcija)
English: Your doctor will check your blood and urine regularly as Ristempa can harm the tiny filters inside your kidneys (glomerulonephritis).
Croatian: Vaš će liječnik redovito provjeravati Vašu krv i mokraću jer Ristempa može oštetiti sitne filtere unutar Vaših bubrega (glomerulonefritis).
English: Ristempa therapy should be initiated and supervised by physicians experienced in oncology and/or haematology.
Croatian: Liječenje Ristempom mora započeti i nadzirati liječnik s iskustvom u onkologiji i/ili hematologiji.
English: Your doctor may decide that it would be more convenient for you to inject Ristempa yourself.
Croatian: Vaš liječnik može odlučiti da će Vama biti pogodnije ako si sami injicirate Ristempu.
English: Single doses of 300 µg/kg have been administered subcutaneously to a limited number of healthy volunteers and patients with non-small cell lung cancer without serious adverse reactions.
Croatian: Jednokratna doza od 300 g/kg primijenjena je supkutano ograničenom broju zdravih dobrovoljaca i bolesnika s rakom pluća ne-malih stanica bez pojave ozbiljnih reakcija.
English: In animal models concomitant administration of Ristempa and 5-fluorouracil (5-FU) or other antimetabolites has been shown to potentiate myelosuppression.
Croatian: Na životinjskim modelima se pokazalo da je istodobna primjena Ristempe i 5-fluorouracila (5-FU) ili drugih antimetabolita potencirala mijelosupresiju.
English: What you need to know before you use Ristempa
Croatian: Što morate znati prije nego počnete primjenjivati Ristempu
English: After releasing the plunger, the pre-filled syringe safety guard will safely cover the injection needle.
Croatian: Nakon što ste oslobodili klip, sigurnosni štitnik napunjene štrcaljke će prekriti iglu za injekciju.
English: 9/l after the expected nadir, this medicine should be discontinued immediately.
Croatian: 9/l, liječenje ovim lijekom treba odmah prekinuti.
English: If you develop or are likely to develop cancers of the blood, you should not use Ristempa, unless instructed by your doctor.
Croatian: Ukoliko imate ili postoji neposredna opasnost od razvoja oblika raka krvi, ne biste trebali primjenjivati Ristempu, osim u slučaju da je to savjet Vašeg liječnika.
English: The most common adverse reaction reported was bone pain (see section 5.1 and 5.2).
Croatian: Najčešće prijavljena nuspojava bila je bol u kostima (vidjeti dio 5.1 i 5.2).
English: For further instructions on how to inject yourself with Ristempa, please read the section at the end of this leaflet.
Croatian: Dodatne upute o tome kako samostalno injicirati Ristempu potražite u dijelu na kraju ove Upute o lijeku.
English: Do not use any Ristempa that is left in the syringe.
Croatian: Ne koristite Ristempu koja je ostala u štrcaljki.
English: • It is important that you do not try to give yourself the injection unless you have received training from your doctor or healthcare provider.
Croatian: • Važno je da ne pokušavate dati sebi injekciju ukoliko niste prošli obuku kod svojeg liječnika ili zdravstvenog djelatnika
English: This can be a sign of Acute Respiratory Distress Syndrome (ARDS)
Croatian: To može biti znak akutnog respiratornog distres sindroma odraslih (ARDS);
English: However, the long-term effects of Ristempa have not been established in acute myeloid leukaemia; therefore, it should be used with caution in this patient population.
Croatian: Međutim, dugoročni učinci Ristempe na akutnu mijeloičnu leukemiju nisu ustanovljeni, stoga se lijek mora primjenjivati s oprezom u toj populaciji bolesnika.
English: Therefore, physicians should use caution when prescribing Ristempa in patients with sickle cell trait or sickle cell disease, should monitor appropriate clinical parameters and laboratory status and be attentive to the possible association of this medicine with splenic enlargement and vaso-occlusive crisis.
Croatian: Stoga liječnici trebaju s oprezom prepisivati Ristempu u bolesnika s nasljednim obilježjem srpastih stanica ili s bolesti srpastih stanica, pažljivo pratiti odgovarajuće kliničke i laboratorijske parametre te paziti na moguću povezanost ovog lijeka s povećanjem slezene i vazookluzivnom krizom.
English: Important: read the package leaflet before handling pre-filled syringe.
Croatian: Važno: Pročitajte Uputu o lijeku prije rukovanja napunjenom štrcaljkom.
English: The mechanism of vasculitis in patients receiving Ristempa is unknown.
Croatian: Mehanizam nastanka vaskulitisa u bolesnika koji primaju Ristempu nije poznat.
English: Ristempa may be used if it is accidentally frozen for a single period of less than 24 hours.
Croatian: Ristempa se može upotrijebiti ako je bio slučajno zamrznut jednokratno i kraće od 24 sata.
English: Sweet's syndrome (acute febrile dermatosis) Cutaneous vasculitis
Croatian: Sweetov sindrom (akutna febrilna dermatoza) Kožni vaskulitis
English: Ristempa is not recommended during pregnancy and in women of childbearing potential not using contraception.
Croatian: Ne preporučuje se koristiti lijek Ristempa tijekom trudnoće niti u žena reproduktivne dobi koje ne koriste kontracepciju.
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu
Croatian: Detaljne informacije o ovom lijeku dostupne su na web stranici Europske agencije za lijekove: http://www.ema.europa.eu
English: Ristempa contains sorbitol (a type of sugar).
Croatian: Ristempa sadrži sorbitol (jedan oblik šećera).
English: The safety and efficacy of Ristempa administration in de novo AML patients aged  55 years with cytogenetics t(15;17) have not been established.
Croatian: Sigurnost i djelotvornost primjene Ristempe u bolesnika s de novo AML mlađih od 55 godina s citogenetskim nalazom t(15;17) nisu utvrđeni.
English: This adverse reaction was identified through post-marketing surveillance but not observed in randomised, controlled clinical trials in adults.
Croatian: Ove su nuspojave uočene nakon stavljanja lijeka u promet, ali ne i u randomiziranim, kontroliranim kliničkim ispitivanjima u odraslih bolesnika.
English: Separate additional insert:
Croatian: Zasebni dodatni umetak:
English: Please tell your doctor immediately if you have any of the following or combination of the following side effects:
Croatian: Recite odmah svom liječniku ako imate neku od navedenih ili kombinaciju navedenih nuspojava:
English: How to store Ristempa
Croatian: Kako čuvati Ristempu
English: Do not use Ristempa
Croatian: Nemojte primjenjivati Ristempu
English: The safety and efficacy of Ristempa for the mobilisation of blood progenitor cells in patients or healthy donors has not been adequately evaluated.
Croatian: Sigurnost i djelotvornost Ristempe u mobilizaciji krvotvornih matičnih stanica u bolesnika ili zdravih davatelja nije odgovarajuće ispitana.
English: Common (≥ 1/100 to < 1/10) cases of leukocytosis (White Blood Count [WBC] > 100 x 10
Croatian: Prijavljeni su česti (≥ 1/100 do < 1/10) slučajevi leukocitoze (broj leukocita > 100 x 10
English: In the absence of growth factor support, this regimen has been reported to result in a mean duration of grade 4 neutropenia of 5 to7 days, and a 30-40% incidence of febrile neutropenia.
Croatian: Bez potpore faktorom rasta primijećeno je da takav režim rezultira srednjim trajanjem neutropenije 4. stupnja od 5 do 7 dana te incidenciju pojave febrilne neutropenije od 30 do 40%.
English: In an open label, single dose study (n = 31) various stages of renal impairment, including end-stage renal disease, had no impact on the pharmacokinetics of pegfilgrastim.
Croatian: U otvorenom ispitivanju pojedinačne doze (n = 31) različiti stadiji oštećenja funkcije bubrega, uključujući terminalni stadij bolesti, nisu utjecali na farmakokinetiku pegfilgrastima.
English: Ristempa has no or negligible effect on the ability to drive or use machines.
Croatian: Ristempa ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: • have an allergy to latex.
Croatian: • ako ste alergični na lateks.
English: In order to improve the traceability of granulocyte-colony stimulating factors (G-CSFs), the trade name of the administered product should be clearly recorded in the patient file.
Croatian: Kako bi se poboljšalo praćenje lijekova koji sadrže faktore stimulacije granulocitnih kolonija (G-CSF), zaštićeno ime primijenjenog lijeka mora se jasno navesti u bolesnikovoj medicinskoj dokumentaciji.
English: Ristempa may be exposed to room temperature (not above 30C) for a maximum single period of up to 72 hours.
Croatian: Ristempa se može izložiti sobnoj temperaturi (ne višoj od 30 C) jednokratno, tijekom najviše 72 sata.
English: • serious allergic reactions, including anaphylaxis (weakness, drop in blood pressure, difficulty
Croatian: • ozbiljne alergijske reakcije, uključujući anafilaksiju (slabost, pad krvnog tlaka, otežano disanje,
English: Each pre-filled syringe contains 30 mg sorbitol (E420) Each pre-filled syringe contains less than 1 mmol (23 mg) sodium (see section 4.4).
Croatian: Jedna napunjena štrcaljka sadrži 30 mg sorbitola (E420) Jedna napunjena štrcaljka sadrži manje od 1 mmol (23 mg) natrija (vidjeti dio 4.4).
English: Your doctor has given you Ristempa to encourage your bone marrow (part of the bone which makes blood cells) to produce more white blood cells that help your body fight infection.
Croatian: Liječnik Vam je propisao Ristempu za poticanje funkcije koštane srži (dio kosti koji stvara krvne stanice) kako bi stvorila više bijelih krvnih stanica za borbu tijela protiv infekcija.
English: If you have forgotten a dose of Ristempa, you should contact your doctor to discuss when you should inject the next dose
Croatian: Ako si zaboravite dati dozu Ristempe, upitajte liječnika kada biste trebali injicirati sljedeću dozu.
English: In such circumstances Ristempa should be discontinued at the discretion of the physician and the appropriate treatment given (see section 4.8).
Croatian: U takvim slučajevima prema procjeni liječnika primjenu Ristempe treba prekinuti i primijeniti odgovarajuće liječenje (vidjeti dio 4.8).
English: What Ristempa looks like and contents of the pack Ristempa is a clear, colourless solution for injection in a pre-filled syringe (6 mg/0.6 ml).
Croatian: Kako Ristempa izgleda i sadržaj pakiranja Ristempa je bistra, bezbojna otopina za injekciju u napunjenoj štrcaljki (6 mg/0,6 ml).
English: Pre-filled syringe (Type I glass), with a rubber stopper and a stainless steel needle with or without an automatic needle guard.
Croatian: Napunjena štrcaljka (staklo tipa I), s gumenim čepom i s iglom od nehrđajućeg čelika, sa ili bez automatskog štitnika za iglu.
English: A Remove the pre-filled syringe tray from the package and gather the supplies needed for your injection: alcohol wipes, a cotton ball or gauze pad, a plaster and a sharps disposal container
Croatian: Izvadite podlogu napunjene štrcaljke iz pakiranja i prikupite pribor potreban za davanje injekcije: alkoholne maramice, pamučnu vatu ili jastučić gaze, flaster i spremnik za odlaganje oštrih predmeta (nije uključeno).
English: Capillary Leak Syndrome, which can be life-threatening if treatment is delayed, has been reported as uncommon (≥ 1/1,000 to < 1/100) in cancer patients undergoing chemotherapy following administration of granulocyte colony-stimulating factors; see section 4.4 and section “Description of selected adverse reactions” below.
Croatian: Sindrom povećane propusnosti kapilara, koji može biti životno ugrožavajući ukoliko se ne počne liječiti na vrijeme, prijavljen je manje često (≥ 1/1000 do < 1/100) u bolesnika s rakom koji su na kemoterapiji nakon primjene faktora stimulacije rasta granulocita; vidjeti dio 4.4 i dio „Opis odabranih nuspojava“ ispod.
English: For a more comfortable injection, leave the pre-filled syringe at room temperature for about 30 minutes before injecting.
Croatian: Za ugodniju primjenu, ostavite napunjenu štrcaljku na sobnoj temperature kroz oko 30 minuta prije injiciranja.
English: You may be encouraged to enrol in Amgen's Pregnancy Surveillance programme.
Croatian: Možda će Vas potaknuti da se pridružite Amgenovom programu praćenja trudnoće.
English: What Ristempa contains - The active substance is pegfilgrastim.
Croatian: Što Ristempa sadrži - Djelatna tvar je pegfilgrastim.
English: In clinical trials, Ristempa has been safely administered 14 days before chemotherapy.
Croatian: Ristempa sigurno primjenjivala 14 dana prije kemoterapije.
English: EU/1/15/996/001 1 pack EU/1/15/996/003 1 pack with needle guard
Croatian: EU/1/15/996/001 pakiranje od 1 EU/1/15/996/003 pakiranje od 1 sa štitnikom za iglu
English: Uncommon side effects (may affect up to 1 in 100 people): • allergic-type reactions, including redness and flushing, skin rash, and raised areas of the skin
Croatian: Manje česte nuspojave (mogu se javiti u manje od 1 na 100 osoba): • reakcije alergijskog tipa, uključujući crvenilo i navale crvenila, osip na koži, izdignuta područja
English: Sickle cell crisis2; Splenomegaly Splenic rupture2
Croatian: Kriza srpastih stanica2, Splenomegalija2