FrancophonIA/ELRC3.0 huggingface dataset:
English: See Table 6 for undesirable effects reported in Caelyx-treated patients.
Croatian: Vidjeti tablicu 6 zbog nuspojava uočenih u bolesnica liječenih Caelyxom.
English: Caelyx is a long-circulating pegylated liposomal formulation of doxorubicin hydrochloride.
Croatian: Caelyx je pegilirani liposomalni oblik doksorubicinklorida koji se dugo zadržava u krvotoku.
English: With Caelyx, the encapsulation of doxorubicin hydrochloride in pegylated liposomes results in these effects having a differing strength, as follows.
Croatian: Kod Caelyxa, inkapsuliranostdoksorubicinkloridau pegiliranim liposomimarazultirarazličitom jačinom ovih učinaka, kako je dalje navedeno.
English: The pharmacokinetics of Caelyx over the dose range of 10 mg/m2 to 60 mg/m2 was best described by a two compartment non-linear model with zero order input and Michaelis-Menten elimination.
Croatian: 60 mg/m 2 najbolje opisuje nelinearni model u dva odjeljka s eliminacijom prema kinetici nultog reda i Michaelis-Mentenovoj kinetici.
English: Decreased appetite Anorexia
Croatian: Manje često anoreksija
English: Gastrointestinal disorders very common nausea common diarrhoea, stomatitis, vomiting, mouth ulceration, abdominal pain, glossitis, constipation, nausea and vomiting
Croatian: Poremećaji probavnog sustava vrlo često mučnina često proljev, stomatitis, povraćanje, ulceracije u ustima, bolovi u trbuhu, glositis, konstipacija, mučnina i povraćanje
English: If you are being treated for multiple myeloma, and have already received at least 1 prior therapy, Caelyx will be administered at a dose of 30 mg per square metre of your body surface area (based on your height and weight) as a 1 hour intravenous infusion on day 4 of the bortezomib 3 week regimen immediately after the bortezomib infusion.
Croatian: Ako se liječite zbog multiplog mijeloma, a već ste prethodno primili najmanje 1 liniju liječenja, Caelyx ćete primati u dozi od 30 mg po kvadratnom metru površine tijela (na temelju
English: Nervous system disorders common dizziness uncommon paresthesia
Croatian: Poremećaji živčanog sustava često omaglica manje često parestezija
English: Leukopaenia, anaemia, thrombocytopaenia
Croatian: Često leukopenija, anemija, trombocitopenija hipokromna anemija
English: How to store Caelyx
Croatian: Kako čuvati Caelyx
English: As there is no experience with Caelyx in patients who have had splenectomy, treatment with Caelyx is not recommended.
Croatian: Bolesnici s Kaposijevim sarkomom povezanim s AIDS-om koji su splenektomirani Budući da nema iskustva s primjenom Caelyxa u bolesnika koji su imali splenektomiju, ne preporučuje se liječenje ovim lijekom.
English: Very rare cases of secondary oral cancer have been reported in patients with long-term (more than one year) exposure to Caelyx or those receiving a cumulative Caelyx dose greater than 720 mg/m2.
Croatian: Vrlo su rijetko prijavljeni slučajevi sekundarnog karcinoma usta u bolesnika koji su dugotrajno (duže od jedne godine) izloženi Caelyxu ili u onih koji primaju ukupnu dozu Caelyxa veću od 720 mg/m Slučajevi sekundarnog karcinoma usta bili su dijagnosticirani i tijekom liječenja Caelyxom, kao i do 6 godina nakon posljednje doze.
English: The mean intrinsic clearance of Caelyx was 0.030 l/h/m (range 0.008 to 0.152 l/h/m2) and the mean central volume of distribution was 1.93 l/m
Croatian: Prosječni intrinzički klirens bio je 0,016 l/h/m2 (raspon 0,008 - 0,027 l/h/m2), prosječni centralni volumen raspodjele bio je
English: The mean apparent half-life was 71.5 hours (range
Croatian: Prosječni prividni poluvijek bio je 75,0 sati (raspon 36,1 - 125 sati).
English: Serious and sometimes life-threatening infusion reactions, which are characterised by allergic-like or anaphylactoid-like reactions, with symptoms including asthma, flushing, urticarial rash, chest pain, fever, hypertension, tachycardia, pruritus, sweating, shortness of breath, facial oedema, chills, back pain, tightness in the chest and throat and/or hypotension may occur within minutes of starting the infusion of Caelyx.
Croatian: Nakon početka infuzije Caelyxa, u roku od nekoliko minuta mogu nastupiti ozbiljne, po nekad po život opasne reakcije na infuziju, nalik alergijskim ili anafilaktoidnim reakcijama, uz simptome koji uključuju astmu, napade crvenila, urtikariju, bolove u prsištu, vrućicu, hipertenziju, tahikardiju, svrbež, znojenje, nedostatak daha, edem lica, zimice, bolove u leđima, stezanje u prsištu i grlu i/ili hipotenziju.
English: Fatigue, weakness, pain
Croatian: Manje često umor, slabost, bol
English: Myelosuppression associated with anaemia, thrombocytopaenia, leukopaenia, and rarely febrile neutropaenia, has been reported in Caelyx-treated patients.
Croatian: U bolesnika liječenih Caelyxom zabilježena je mijelosupresija praćena anemijom, trombocitopenijom, leukopenijom i, rijetko, febrilnom neutropenijom.
English: It is recommended that all patients receiving Caelyx routinely undergo frequent ECG monitoring.
Croatian: Preporučuje se rutinsko ponavljanje EKG pregleda u svih bolesnika koji primaju Caelyx.
English: CAELYX LABEL 50 mg/25 ml
Croatian: CAELYX NALJEPNICA 50 mg/25 ml
English: Ventricular arrhythmia
Croatian: Srčani poremećaji Često ventrikularna aritmija
English: CAELYX LABEL 20 mg/10 ml
Croatian: CAELYX NALJEPNICA 20 mg/10 ml
English: The treatment HR for PFS when adjusted for prognostic variables was consistent with PFS for the ITT population.
Croatian: Omjer rizika za preživljenje bez napredovanja bolesti pri liječenju, nakon prilagođivanja na prognostičke varijable bio je u skladu s preživljenjem bez napredovanja bolesti u cjelokupne populacije uključene u ispitivanje (ITT populacija).
English: Blood and lymphatic system disorders very common neutropaenia, anaemia, leukopaenia common thrombocytopaenia
Croatian: Poremećaji krvi i limfnog sustava vrlo često neutropenija, anemija, leukopenija često trombocitopenija
English: Caelyx must be handled and disposed of in a manner consistent with that of other anticancer medicinal products.
Croatian: Način rukovanja Caelyxom i njegovo uklanjanje moraju biti sukladni načinu rukovanja i uklanjanja drugih antitumorskih lijekova.
English: Hypotension, orthostatic hypotension, flushing, hypertension, phlebitis
Croatian: Krvožilni poremećaji Često hipotenzija, ortostatska hipotenzija, napadi crvenila, hipertenzija, flebitis
English: Secondary oral neoplasms
Croatian: Sekundarne neoplazme u ustima
English: Constipation, dyspepsia, mouth ulceration
Croatian: Manje često konstipacija, dispepsija, ulceracije u ustima
English: Anaphylactoid response
Croatian: Anafilaktoidni odgovor
English: Eye disorders Common
Croatian: Poremećaji oka Često konjunktivitis
English: AE by body system Breast cancer All severities n=254
Croatian: Karcinom dojke svi stupnjevi težine n=254
English: Mouth ulceration, esophagitis, nausea and vomiting, gastritis, dysphagia, dry mouth, flatulence, gingivitis, taste perversion
Croatian: Često bolovi u trbuhu, dispepsija, ulceracije u ustima mučnina, stomatitis, povraćanje, bolovi u trbuhu, proljev ulceracije u ustima, ezofagitis, mučnina i povraćanje, gastritis, disfagija, suha usta, nadutost, gingivitis, promjene okusa
English: Folliculitis, fungal infection, cold sores (non-herpetic), upper respiratory tract infection
Croatian: Infekcije i infestacije Često faringitis folikulitis, gljivična infekcija, groznica na usnama (neherpetična), infekcija gornjih dišnih puteva
English: Mouth ulceration, constipation, vomiting
Croatian: Manje često ulceracije u ustima, zatvor, povraćanje
English: It must not be used interchangeably with other formulations of doxorubicin hydrochloride.
Croatian: Ne smije se naizmjence primjenjivati s drugim oblicima doksorubicinklorida.
English: The mean intrinsic clearance was 0.021 l/h/m2 (range 0.009-0.041 l/h/m2), the mean central volume of distribution was 1.95 l/m 2 (range 1.67-2.40 l/m 2).
Croatian: (raspon 0,009 - 0,041 l/h/m 2), a prosječni centralni volumen raspodjele bio je 1,95 l/m
English: Breast cancer program
Croatian: Program liječenja karcinoma dojke
English: Ovarian cancer patients
Croatian: Bolesnice s karcinomom jajnika
English: Weight decreased
Croatian: Prekinuti primjenu
English: Arthralgia, myalgia, muscle spasms, muscular weakness, musculoskeletal pain, musculoskeletal chest pain
Croatian: Poremećaji mišićno-koštanog sustava i vezivnog tkiva Često bol u ekstremitetima artralgija, mialgija, spazmi mišića, mišićna slabost, mišićno-koštana bol, mišićno-koštana bol u prsištu
English: Breast cancer patients
Croatian: Bolesnice s karcinomom dojke
English: Neutropaenia
Croatian: Doziranje
English: Vesiculobullous rash, pruritus, exfoliative dermatitis, skin disorder, maculopapular rash, sweating, acne, skin ulcer
Croatian: Često suha koža, promjene boje kože alopecija, osip vezikulobulozni osip, pruritus, eksfolijativni dermatitis, kožni poremećaj, makulopapularni osip, znojenje, akne, kožni ulkus
English: Stomatitis
Croatian: TROMBOCITI
English: B. PACKAGE LEAFLET
Croatian: Tablica 2. Stomatitis
English: At lower doses (10 mg/m2-20 mg/m
Croatian: Farmakokinetika Caelyxa u manjim dozama (10 mg/m 2 - 20 mg/m 2) je linearna.
English: Undesirable effects observed in patients with AIDS-related KS according to CIOMS III frequency categories
Croatian: om prema kategorijama učestalosti po CIOMS III
English: 73 l/h/m2).
Croatian: (raspon 1,67 - 2,40 l/m 2).
English: Dry skin, skin discolouration, pigmentation abnormal, erythema
Croatian: Često suha koža, promjene boje kože, poremećaj pigmentacije, eritem osip bulozna erupcija, dermatitis, eritematozni osip, poremećaj noktiju, ljuskava koža
English: Children and adolescents
Croatian: Trudnoća i dojenje
English: AIDS-related KS
Croatian: Kaposijev sarkom povezan s AIDS-om
English: CIOMS III AE by body system Ovarian cancer All severities n=512
Croatian: Karcinom jajnika svi stupnjevi težine n=512
English: 5% of the total dose should be infused slowly over the first 15 minutes.
Croatian: U bolesnika s reakcijom na infuziju, istu je potrebno prilagoditi na sljedeći način: 5% ukupne doze treba dati polaganom infuzijom tijekom prvih 15 minuta.
English: Renal Impairment
Croatian: Često nesanica tjeskoba
English: Weakness, fever, pain Asthenia, mucositis NOS
Croatian: Često slabost, vrućica, bol astenija, nespecificirani mukozitis edem, edem nogu.
English: Scrotal erythema
Croatian: Palmarno - plantarna eritrodizestezija
English: Treatment related undesirable effects reported in breast cancer clinical trials (50 mg/m2 every 4 weeks) (Caelyx-treated patients) by severity, MedDRA system organ class and preferred term
Croatian: Tablica 5. Nuspojave povezane s liječenjem, uočene u kliničkim ispitivanjima karcinoma dojke (50 mg/m svaka 4 tjedna) (bolesnice liječene Caelyxom) po stupnju težine, MedDRA klasifikaciji organskih sustava i MedDRA izrazu vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100)
English: There was a significant improvement in the primary endpoint of time to progression (TTP) for patients treated with combination therapy of Caelyx plus bortezomib compared to patients treated with bortezomib monotherapy as indicated by a risk reduction (RR) of 35% (95% CI: 21-47%), p < 0.0001, based on 407 TTP events.
Croatian: U bolesnika liječenih kombiniranom terapijom Caelyxa i bortezomiba nastupilo je značajno poboljšanje vremena do napredovanja bolesti (TTP) kao primarnog ishoda ispitivanja u usporedbi s bolesnicima liječenima monoterapijom bortezomibom, kao što je pokazalo smanjenje rizika (RR) za
English: Pneumonia, nasopharyngitis, upper respiratory tract infection, oral candidiasis
Croatian: Infekcije i infestacije Često herpes simpleks, herpes zoster herpes zoster pneumonija, nazofaringitis, infekcija gornjih dišnih puteva, oralna kandidijaza
English: Constipation, diarrhoea, nausea, stomatitis, vomiting
Croatian: Poremećaji probavnog sustava Vrlo često konstipacija, proljev, mučnina, stomatitis, povraćanje
English: Abdominal pain, constipation, diarrhoea, dyspepsia, mouth ulceration
Croatian: Često bolovi u trbuhu, konstipacija, proljev, dispepsija, ulceracije u ustima bolovi u trbuhu, proljev, mučnina, stomatitis bol u ustima
English: Nausea, diarrhoea, vomiting, constipation, stomatitis
Croatian: Poremećaji probavnog sustava Vrlo često mučnina, proljev, povraćanje, konstipacija, stomatitis
English: Immune system disorders Common
Croatian: Poremećaji imunološkog sustava Često alergijske reakcije
English: Headache, dizziness, neuropathy, hypertonia
Croatian: Poremećaji živčanog sustava Često parestezija, somnolencija glavobolja, omaglica, neuropatija, hipertonija
English: Upper abdominal pain, mouth ulceration, dry mouth, dysphagia, aphthous stomatitis
Croatian: Često bolovi u trbuhu, dispepsija mučnina, proljev, povraćanje, stomatitis bolovi u gornjem dijelu trbuha, ulceracije u ustima, suha usta, disfagija, aftozni stomatitis
English: The mean intrinsic clearance was 0.016 l/h/m2 (range 0.008-0.027 l/h/m2), the mean central volume of distribution was 1.46 l/m 2 (range 1.10-1.64 l/m 2).
Croatian: 1,46 l/m 2 (raspon 1,10 - 1,64 l/m 2).
English: Lacrimation, blurred vision
Croatian: Poremećaji oka Često suzenje, zamagljen vid
English: 10 vials 50 mg/25 ml
Croatian: 1 bočica 10 bočica 50 mg/25 ml
English: • you are a smoker (as this may increase the risk of dental problems)
Croatian: • pušač ste (jer to može povećati rizik od problema sa zubima)
English: Do not administer the injection to yourself.
Croatian: Nemojte sami sebi davati injekciju.
English: • you have cancer.
Croatian: • imate rak.
English: A healthy lifestyle will also help you to get the most benefit from your treatment.
Croatian: Zdrav način života pomaže Vam da imate maksimalnu korist od liječenja.
English: General advice
Croatian: Općeniti savjet
English: Please consult your doctor
Croatian: Posavjetujte se s liječnikom.
English: Before receiving treatment, tell your doctor/nurse (health care professional) if:
Croatian: Prije početka liječenja obavijestite svog liječnika/medicinsku sestru (zdravstvenog djelatnika) ako:
English: The content of the vial is to be used as follows:
Croatian: Sadržaj bočice treba koristiti na sljedeće načine:
English: In table 1 a complete list of known adverse reactions is presented.
Croatian: Tablici 1 prikazan je popis svih poznatih nuspojava.
English: • If you have any disturbance of mineral metabolism (such as vitamin D deficiency)
Croatian: • ako imate poremećaj metabolizma minerala (kao što je nedostatak vitamina D)
English: A limited number of patients (50 patients) have received a second infusion for hypercalcaemia.
Croatian: Ograničeni broj bolesnika (50 bolesnika) primilo je drugu infuziju za hiperkalcijemiju.
English: • if you have high or low levels of vitamin D, calcium or any other minerals.
Croatian: • ako imate visoke ili niske razine vitamina D, kalcija ili drugih minerala
English: Elderly population (>65 years)
Croatian: Starija populacija (>65 godina)
English: • It helps to prevent other bone problems that may need surgery or radiotherapy.
Croatian: • Pomaže spriječiti druge poteškoće s kostima koje bi mogle zahtijevati operaciju ili radioterapiju.
English: These could be signs of bone damage in the ear.
Croatian: To mogu biti znakovi oštećenja kostiju u uhu.
English: The injection should be given into the vein by a physician or qualified/trained health care worker.
Croatian: Injekciju u venu mora dati liječnik ili kvalificiran/obučeni zdravstveni radnik.
English: % of Patients with Response
Croatian: Bolesnici s odgovorom (%)
English: • Needles and syringes should never be reused.
Croatian: • Igle i štrcaljke ne smiju se ponovo upotrijebiti ni u kojem slučaju.
English: • not smoking and not drinking too much alcohol
Croatian: • nepušenje i nekonzumiranje prekomjernih količina alkohola
English: Your doctor may take steps to correct such changes and may give you an injection containing these minerals.
Croatian: Vaš liječnik može poduzeti potrebne mjere za rješavanje tih poremećaja i može Vam dati injekciju s tim mineralima.
English: • Placing used sharps containers in the household waste should be avoided.
Croatian: • Odlaganje spremnika za odladanje oštrih predmeta u kućni otpad treba izbjegavati.
English: This was demonstrated in both the primary analysis at one year and in the confirmatory analysis at two years endpoint (Table 2).
Croatian: To je dokazano primarnom analizom nakon jedne godine i potvrdnom analizom nakon dvije godine (tablica
English: The optimal duration of bisphosphonate treatment for osteoporosis has not been established.
Croatian: Optimalno trajanje terapije osteoporoze bisfosfonatima nije ustanovljeno.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2° C to 8°C unless dilution has taken place in controlled and validated aseptic condition.
Croatian: Ako se ne primijeni odmah, za vrijeme i uvjete čuvanja prije primjene odgovoran je korisnik, a oni normalno ne bi trebali biti duži od 24 sata pri temperaturi od 2 do 8°C, osim ako se razrjeđivanje provelo u kontroliranim i validiranim aseptičkim uvjetima.
English: • you have previously been treated with a bisphosphonate (used to treat or prevent bone disorders)
Croatian: • ranije ste liječeni bisfosfonatima (koji se koriste za liječenje ili sprječavanje poremećaja kostiju)
English: • stomach problems such as ‘“gastroenteritis”' or ‘“gastritis”'
Croatian: • problemi sa želucem kao “gastroenteritis” ili “gastritis”
English: • if you have, or had in the past, low blood calcium.
Croatian: • ako imate ili ste imali u prošlosti nisku razinu kalcija u krvi.
English: Do not use this medicine if you notice that the solution is not clear or contains particles.
Croatian: Ovaj lijek se ne smije upotrijebiti ako primijetite da otopina nije bistra ili sadrži čestice.
English: Your doctor may adjust your dose and duration of intravenous infusion if you have kidney problems.
Croatian: Liječnik Vam može prilagoditi dozu i trajanje intravenske infuzije ukoliko imate problema s bubrezima.
English: At the menopause, a woman's ovaries stop producing the female hormone, oestrogen, which helps to keep her skeleton healthy.
Croatian: U menopauzi ženini jajnici prestaju proizvoditi ženski hormon, estrogen, koji pomaže očuvanju zdravog skeleta.
English: In growing rats, there was no evidence of impaired mineralisation even at doses greater than 5,000 times the dose required for osteoporosis treatment.
Croatian: Za štakore u rastu ne postoje dokazi o oštećenoj mineralizaciji, čak i pri dozama 5000 puta većima od doze potrebne za liječenje osteoporoze.
English: • you are taking medicines called corticosteroids (such as prednisolone or dexamethasone)
Croatian: • uzimate lijekove koji se zovu kortikosteroidi (kao što je prednizolon ili deksametazon)
English: Manufacturer Accord Healthcare Limited Sage House
Croatian: Accord Healthcare Limited Sage House
English: • if you have, or have ever had low levels of calcium in your blood Do not receive this medicine if any of the above apply to you.
Croatian: • ako imate ili ste ikada imali nisku razinu kalcija u krvi Ukoliko se bilo što od gore navedenog odnosi na Vas ne smijete primiti ovaj lijek.
English: Possible risk factors for osteonecrosis of the external auditory canal include steroid use and chemotherapy and/or local risk factors such as infection or trauma.
Croatian: Mogući faktori rizika za osteonekrozu vanjskog slušnog hodnika uključuju primjenu steroida i kemoterapije i/ili postojanje lokalnih faktora rizika kao što je infekcija ili trauma.
English: In order to reduce the risk of developing osteonecrosis of the jaw, there are some precautions you should take.
Croatian: Radi smanjenja rizika od nastanka osteonekroze čeljusti trebate poduzeti određene mjere opreza.
English: Pharmacokinetics in special clinical situations
Croatian: Farmakokinetika u posebnim kliničkim situacijama
English: Body weight gain was decreased in F1 offspring in rats.
Croatian: Smanjeni porast tjelesne težine primijećen je u F1 potomstvu štakora.
English: • smoking cigarettes, or drinking too much alcohol
Croatian: • pušenje ili prekomjerno konzumiranje alkohola
English: • you don't receive routine dental care or have not had a dental check up for a long time
Croatian: • ne odlazite redovito na stomatološke kontrole ili niste odavno išli na stomatološku kontrolu
English: Each pack contains 1 vial.
Croatian: Jedno pakiranje sadrži 1 bočicu.
English: Date of first authorisation: 19 November 2012 Date of latest renewal: 18 September 2017
Croatian: Datum posljednje obnove odobrenja: 18. rujna 2017
English: • Talk to your doctor if you have ear pain, discharge from the ear, and/or an ear infection.
Croatian: • Razgovarajte s liječnikom ako imate bolove u uhu, iscjedak iz uha i/ili infekciju uha.
English: These symptoms are typically in association with the first dose, generally of short duration, mild or moderate in intensity, and usually resolve during continuing treatment without requiring remedial measures (please see paragraph “Influenza like illness”).
Croatian: Ti simptomi tipično su povezani s prvom dozom, općenito su kratkog trajanja, srednjeg ili umjerenog intenziteta i uglavnom prolaze tijekom kontinuiranog liječenja bez potrebe za mjerama ublažavanja (vidjeti odlomak „Bolest slična gripi“).
English: Serum CTX reduction was maintained over the 2 years, with more than half of the patients identified as responders in both treatment groups.
Croatian: Smanjenje razine CTX-a u serumu održalo se dvije godine u više od polovice bolesnika koji su odgovorili na liječenje u obje liječene skupine.
English: • a condition affecting the blood vessels in your brain called ‘“cerebrovascular disorder”' (stroke or brain bleeding)
Croatian: • stanje koje pogađa krvne žile mozga zvano “cerebrovaskularni poremećaj” (moždani udar ili krvarenje)
English: The incidence of clinical vertebral fractures was also significantly reduced by 49 % after 3 years (p=0.011).
Croatian: Incidencija kliničkih prijeloma kralježaka također je znatno smanjena i to za 49% nakon 3 godine (p=0,011).
English: Specific studies for the 3-monthly dosing regimen have not been performed.
Croatian: Nisu provedena specifična ispitivanja za tromjesečnu primjenu.
English: This leaflet was last revised in {date}.
Croatian: Ova uputa je zadnji puta revidirana u {datum}.
English: • if you are allergic to any other bisphosphonates.
Croatian: • ako ste alergični na druge bisfosfonate
English: • Dispose of the full container according to local requirements or as instructed by your healthcare professional.
Croatian: • Puni spremnik valja zbrinuti sukladno lokalnim propisima ili po naputku zdravstvenih djelatnika.
English: You may be having a serious, potentially life threatening allergic reaction (see section 2).
Croatian: Moguće je da imate ozbiljnu, potencijalno smrtonosnu alergijsku reakciju (vidjeti dio 2).
English: The most frequently reported adverse reactions are arthralgia and influenza-like symptoms.
Croatian: Najčešće prijavljivane nuspojave su artralgija i simptomi nalik gripi.
English: (dead bone tissue) in the jaw bone).
Croatian: (mrtvo koštano tkivo) u čeljusnoj kosti)
English: • If you have or have ever had kidney problems, kidney failure or have needed dialysis, or if you have any other disease that may affect your kidneys
Croatian: • ako imate ili ste ikada imali problema s bubrezima, zatajenje bubrega, ili ako ste trebali dijalizu te ako imate bilo koju drugu bolest koja može utjecati na bubrege
English: • Ibandronic acid Accord is normally given by a doctor or other medical staff who have experience with the treatment of cancer.
Croatian: • Ibandronic acid Accord će Vam obično dati liječnik ili drugi zdravstveni djelatnici koji imaju iskustva u liječenju raka.
English: The person giving the injection should throw away any unused solution and put the used syringe and injection needle into an appropriate disposal container.
Croatian: Osoba koja primjenjuje injekciju treba baciti neiskorištenu otopinu i staviti korištenu štrcaljku i iglu u odgovarajući spremnik za otpad.