FrancophonIA/ELRC3.0 huggingface dataset:
English: Respiratory reactions, including death due to bronchospasm in patients with asthma have been reported following administration of some ophthalmic beta-blockers.
Croatian: Respiratorne reakcije, uključujući smrt zbog bronhospazma kod bolesnika s astmom, zabilježene su nakon lokalne primjene u oko nekih beta-blokatora.
English: • if you have dry eyes or cornea problems.
Croatian: • Ako imate suho oko ili poteškoće s rožnicom.
English: Patients should be instructed to shake the bottle well before use.
Croatian: Bolesnike se mora uputiti da bočicu dobro protresu prije primjene.
English: Beta-blockers should be administered with caution in patients subject to spontaneous hypoglycaemia or to patients with labile diabetes, as beta-blockers may mask the signs and symptoms of acute hypoglycaemia.
Croatian: Beta-blokatori se moraju primjenjivati s oprezom kod bolesnika sklonih spontanoj hipoglikemiji ili bolesnika sa slabo reguliranom šećernom bolešću jer beta-blokatori mogu prikriti znakove i simptome akutne hipoglikemije.
English: Specifically, patients wearing contact lenses have not been studied and careful monitoring of these patients when using brinzolamide is recommended, since carbonic anhydrase inhibitors may affect corneal hydration.
Croatian: Konkretno, nisu ispitivani bolesnici koji nose kontaktne leće te se preporučuje njihovo pozorno praćenje pri primjeni brinzolamida jer inhibitori karboanhidraze mogu utjecati na vlaženje rožnice.
English: In case of accidental ingestion, symptoms of overdose from beta blockade may include bradycardia, hypotension, cardiac failure and bronchospasm.
Croatian: Kod slučajne ingestije, simptomi predoziranja beta-blokatorima mogu uključivati bradikardiju, hipotenziju, zatajenje srca i bronhospazam.
English: There is limited experience with AZARGA in the treatment of patients with pseudoexfoliative glaucoma or pigmentary glaucoma.
Croatian: Iskustva s primjenom AZARGE u liječenju bolesnika s pseudoeksfolijativnim glaukomom ili pigmentnim glaukomom su ograničena.
English: AZARGA has not been studied in patients with severe renal impairment (creatinine clearance <30 ml/min) or in patients with hyperchloraemic acidosis (see section 4.3).
Croatian: AZARGA nije ispitivana u bolesnika s teško oštećenom bubrežnom funkcijom (klirens kreatinina <30 ml/min), ni u onih s hiperkloremijskom acidozom (vidjeti dio 4.3).
English: Decrease of intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension for whom monotherapy provides insufficient IOP reduction (see section 5.1).
Croatian: Snižavanje intraokularnog tlaka (IOT) u odraslih bolesnika s glaukomom otvorenog kuta ili s očnom hipertenzijom u kojih se monoterapijom ne postiže dovoljno sniženje očnog tlaka (vidjeti dio 5.1).
English: Timolol and its metabolites are primarily excreted by the kidneys.
Croatian: Timolol i njegovi metaboliti izlučuju se prvenstveno putem bubrega.
English: 3, eye allergy
Croatian: 3, alergija oka
English: Not known: erectile dysfunction
Croatian: Nepoznato: erektilna disfunkcija
English: AZARGA contains two active substances, brinzolamide and timolol, which work together to reduce pressure within the eye.
Croatian: AZARGA sadrži dvije djelatne tvari brinzolamid i timolol, koje zajedno djeluju na snižavanje tlaka u oku.
English: The combined effect of these two active substances results in additional IOP reduction compared to either compound alone.
Croatian: Kombiniranim učinkom tih dviju djelatnih tvari postiže se veće sniženje očnog tlaka nego svakom tvari posebno.
English: The non-inferiority of AZARGA as compared to dorzolamide 20 mg/ml + timolol 5 mg/ml in the mean IOP reduction was demonstrated across all time-points at all visits.
Croatian: Neinferiornost AZARGE u usporedbi s dorzolamidom 20 mg/ml + timololom 5 mg/ml u snižavanju srednjeg očnog tlaka dokazana je u svim vremenskim točkama, pri svim kontrolnim posjetima.
English: Not known: myalgia
Croatian: Nepoznato: mialgija
English: Beta-blockers are excreted in breast milk.
Croatian: Beta blokatori se izlučuju u majčino mlijeko.
English: The metabolic pathways for the metabolism of brinzolamide involve N-dealkylation, O-dealkylation and oxidation of its N-propyl side chain.
Croatian: Metabolički putovi brinzolamida uključuju N-dealkilaciju, O-dealkilaciju i oksidaciju njegovog N-propilnog bočnog lanca.
English: 5 ml round opaque low density polyethylene bottles with a dispensing plug and white polypropylene screw cap (DROP-TAINER) containing 5 ml suspension.
Croatian: Okrugle, neprozirne bočice od polietilena niske gustoće volumena 5 ml, s nastavkom za kapanje i bijelim polipropilenskim navojnim zatvaračem (DROP-TAINER) koje sadrže 5 ml suspenzije.
English: What you need to know before you use AZARGA
Croatian: Što morate znati prije nego počnete primjenjivati AZARGU
English: At steady state, following administration of AZARGA, the mean plasma Cmax and AUC0-12h of timolol were 27% and 28% lower (Cmax: 0.824 ± 0.453 ng/ml; AUC0-12h: 4.71 ± 4.29 ng·h/ml), respectively, in comparison to the administration of timolol 5 mg/ml (Cmax: 1.13 ± 0.494 ng/ml; AUC0-12h: 6.58 ± 3.18 ng·h/ml).
Croatian: U stanju dinamičke ravnoteže, nakon primjene AZARGE, srednja plazmatska Cmax timolola bila je 27% manja, a AUC0-12h 28% manja (Cmax: 0,824 ± 0,453 ng/ml; AUC0-12h: 4,71 ± 4,29 ng·h/ml) negoli pri primjeni timolola 5 mg/ml (Cmax: 1,13 ± 0,494 ng/ml; AUC0-12h: 6,58 ± 3,18 ng·h/ml).
English: Ocular tissue distribution data in rabbits showed that timolol can be measured in aqueous humour up to 48 hours after administration of AZARGA.
Croatian: Podaci o distribuciji u tkivima oka kunića pokazuju da se timolol može u očnoj vodici mjeriti do 48 sati nakon primjene AZARGE.
English: AZARGA contains benzalkonium chloride
Croatian: AZARGA sadrži benzalkonijev klorid
English: 2, increases in the signs and symptoms of myasthenia gravis
Croatian: 2, pojačani znakovi i simptomi miastenije gravis pospanost
English: • If you are allergic to brinzolamide, medicines called sulphonamides (examples include medicines used to treat diabetes, infections and also diuretics (water tablets)), timolol, betablockers (medicines used to lower blood pressure or to treat heart disease) or any of the other ingredients of this medicine (listed in section 6).
Croatian: • Ako ste alergični (preosjetljivi) na brinzolamid, lijekove koji se nazvaju sulfonamidi (primjeri uključuju lijekove za liječenje šećerne bolesti, infekcija te također diuretike (tablete za izmokravanje)), timolol, beta blokatore (lijekovi koji se koriste za snižavanje krvnog tlaka ili liječenje srčanih oboljenja) ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: • General side effects: difficulty sleeping (insomnia), throat pain, running nose
Croatian: • Opće nuspojave: poteškoće sa spavanjem (nesanica), bol u grlu, curenje iz nosa
English: While taking beta-blockers, patients with a history of atopy or a history of severe anaphylactic reaction to a variety of allergens may be more reactive to repeated challenge with such allergens and unresponsive to the usual doses of adrenaline used to treat anaphylactic reactions.
Croatian: Pri uzimanju beta-blokatora može se dogoditi da bolesnici koji u anamnezi imaju atopiju ili tešku anafilaktičku reakciju na različite alergene mogu jače reagirati kod ponovljenog susreta s takvim alergenima i ne reagirati na uobičajene doze adrenalina koje se daju pri liječenju anafilaktičkih reakcija.
English: Plasma protein binding of brinzolamide is moderate (about 60%).
Croatian: Brinzolamid se umjereno veže na proteine plazme (oko 60%).
English: 1, memory loss
Croatian: 1, gubitak pamćenja
English: Overt cardiac failure, cardiogenic shock.
Croatian: Manifestno zatajenje srca, kardiogeni šok.
English: Studies have shown that timolol does not dialyse readily.
Croatian: Ispitivanja su pokazala da se timolol slabo uklanja dijalizom.
English: In patients with cardiovascular diseases (e.g. coronary heart disease, Prinzmetal's angina and cardiac failure) and hypotension, therapy with beta-blockers should be critically assessed and the therapy with other active substances should be considered.
Croatian: Kod bolesnika s kardiovaskularnim bolestima (npr. koronarna bolest srca, Prinzmetalova angina i zatajenje srca) i hipotenzijom, mora se kritički procijeniti uporabu terapije beta-blokatorima i uzeti u obzir terapiju s drugim djelatnim tvarima.
English: The concomitant administration of AZARGA and oral carbonic anhydrase inhibitors has not been studied and is not recommended (see section 4.5).
Croatian: Istodobna primjena AZARGE i peroralno primjenjenih inhibitora karboanhidraze nije ispitivana i ne preporučuje se (vidjeti dio 4.5).
English: There are no adequate data regarding the use of ophthalmic brinzolamide and timolol in pregnant women.
Croatian: Nema primjerenih podataka vezanih uz oftalmičku primjenu brinzolamida i timolola u trudnica.
English: CARTON FOR SINGLE BOTTLE 5 ml + CARTON FOR 3 x 5 ml BOTTLES
Croatian: KUTIJA ZA JEDNU BOČICU 5 ml + KUTIJA ZA 3 BOČICE x 5 ml
English: When using nasolacrimal occlusion or closing the eyelids, the systemic absorption is reduced.
Croatian: Primjenom nazolakrimalne okluzije ili zatvaranjem vjeđa smanjuje se sustavna apsorpcija.
English: • coronary heart disease (symptoms can include chest pain or tightness, breathlessness or choking), heart failure, low blood pressure
Croatian: • koronarnu bolest srca (simptomi mogu uključivati bol u prsnom košu ili stezanje, nedostatak zraka ili gušenje), zatajenje srca, nizak krvni tlak,
English: Beta blockers can decrease the response to adrenaline used to treat anaphylactic reactions.
Croatian: Beta-blokatori mogu smanjiti odgovor na adrenalin primijenjen u liječenju anafilaktičkih reakcija.
English: Non clinical data do not show any effects of either brinzolamide or timolol on male or female fertility following oral dosing.
Croatian: Neklinički podaci ne upućuju na učinak niti brinzolamida niti timolola na plodnost kod muškaraca ili žena nakon peroralnog doziranja.
English: Serum electrolyte levels (particularly potassium) and blood pH levels should be monitored.
Croatian: Mora se pratiti razina elektrolita u serumu (napose kalija) i pH krvi.
English: If you are worried, talk to your doctor or pharmacist.
Croatian: Ako ste zabrinuti, porazgovarajte s liječnikom ili ljekarnikom.
English: Patients with cardiovascular diseases should be watched for signs of deterioration of these diseases and of adverse reactions.
Croatian: Bolesnici s kardiovaskularnim bolestima moraju biti pod nadzorom zbog znakova pogoršanja bolesti ili pojave nuspojava.
English: • Hypersensitivity to sulphonamides (see section 4.4).
Croatian: • Preosjetljivost na sulfonamide (vidjeti dio 4.4).
English: Following twice daily dosing of AZARGA for 13 weeks, red blood cell (RBC) concentrations of brinzolamide averaged 18.8  3.29 µM, 18.1  2.68 µM and 18.4  3.01 µM at weeks 4, 10 and 15, respectively, indicating that steady-state RBC concentrations of brinzolamide were maintained
Croatian: Nakon primjene AZARGE dvaput na dan tijekom 13 tjedana, prosječna koncentracija brinzolamida u eritrocitima iznosila je 18,8  3,29 µM nakon 4 tjedna, 18,1  2,68 µM nakon 10 tjedana i 18,4  3,01 µM nakon 15 tjedana, što pokazuje da su se koncentracije brinzolamida u stanju dinamičke ravnoteže u eritrocitima održavale.
English: Systemic effects
Croatian: Sustavni učinci
English: In three controlled clinical trials, the ocular discomfort upon instillation of AZARGA was significantly lower than that of dorzolamide 20 mg/ml + timolol 5 mg/ml.
Croatian: U tri kontrolirana klinička istraživanja nelagodan osjećaj u oku nakon ukapavanja AZARGE bio je značajno slabiji negoli pri primjeni dorzolamida 20 mg/ml + timolola 5 mg/ml.
English: Careful monitoring of patients with compromised corneas, such as patients with diabetes mellitus or corneal dystrophies, is recommended.
Croatian: Preporučuje se pozorno praćenje bolesnika s kompromitiranim rožnicama, kao što su bolesnici sa šećernom bolešću ili s distrofijom rožnice.
English: During lactation, the no adverse effect level in the offspring was 5 mg/kg/day.
Croatian: Doza pri kojoj nije bilo štetnih učinaka u podmlatka tijekom dojenja iznosila je 5 mg/kg/dan.
English: • If you have a slow heart beat, heart failure or disorders of heart rhythm (irregular heartbeats).
Croatian: • Ako imate usporene otkucaje srca, zatajenje srca ili srčanu aritmiju (nepravilne otkucaje srca).
English: (see section 4.4 Special warnings and precautions for use), keratopathy
Croatian: Posebna upozorenja i mjere opreza pri uporabi), keratopatija
English: The drop will go in here (picture 1).
Croatian: „prostor“ u koji se i ukapa kap lijeka (slika 1).
English: Developmental toxicity studies in rabbits with oral doses of brinzolamide of up to 6 mg/kg/day (214 times the recommended daily clinical dose of 28 µg/kg/day) revealed no effect on foetal development despite significant maternal toxicity.
Croatian: Istraživanja razvojne toksičnosti u kunića pri peroralnim dozama brinzolamida do 6 mg/kg/dan (doza 214 puta veća od preporučene dnevne kliničke doze koja iznosi 28 µg/kg/dan) nisu pokazala učinak na fetalni razvoj, unatoč značajnoj toksičnosti za majku.
English: However, accumulation of brinzolamide is unlikely as renal elimination is the major route.
Croatian: No nakupljanje brinzolamida nije vjerojatno jer je glavni način njegova uklanjanja putem bubrega.
English: Uncommon: decreased blood pressure Not known: hypotension
Croatian: Manje često: sniženi krvni tlak Nepoznato: hipotenzija
English: Eye drops, suspension (eye drops)
Croatian: Kapi za oko, suspenzija (kapi za oko)
English: • Blood: abnormal liver function values, increased blood chlorine levels, or decreased red blood cell count as seen in a blood test.
Croatian: • Krv: poremećeni nalazi pretraga jetrene funkcije, povišene vrijednosti klora u krvi, smanjeni broj crvenih krvnih stanica uočen krvnom pretragom.
English: What AZARGA looks like and contents of the pack AZARGA is a liquid (white to off-white uniform suspension) supplied in a pack containing one 5 ml plastic bottle with a screw cap or in a pack containing three 5 ml bottles.
Croatian: AZARGA je tekućina (jednolika suspenzija bijele do bjelkaste boje), dostupna u pakiranju koje sadrži jednu plastičnu bočicu od 5 ml s navojnim zatvaračem ili u pakiranju sa tri bočice od 5 ml.
English: In vitro studies show that the metabolism of brinzolamide mainly involves CYP3A4 as well as at least four other isozymes (CYP2A6, CYP2B6, CYP2C8 and CYP2C9).
Croatian: Istraživanja in vitro pokazuju da metabolizam brinzolamida prvenstveno uključuje CYP3A4, ali i najmanje četiri druga izenozima (CYP2A6, CYP2B6, CYP2C8 i CYP2C9).
English: • breathing problems, asthma or chronic obstructive pulmonary disease
Croatian: • poteškoće s disanjem, astmu ili kroničnu opstruktivnu plućnu bolest
English: • Gently press on the base of the bottle to release one drop of AZARGA at a time.
Croatian: • Nježno pritisnite dno bočice, tako da svaki puta istekne samo jedna kap AZARGE.
English: Do not use AZARGA
Croatian: Nemojte primjenjivati AZARGU
English: • Hold the bottle, pointing down, between your thumb and fingers.
Croatian: • Držite bočicu između palca i ostalih prstiju, vrhom okrenutim prema dolje.
English: • diabetes as timolol may mask signs and symptoms of low blood sugar
Croatian: • šećernu bolest jer timolol može prikriti znakove i simptome niskog šećera u krvi
English: AZARGA should be used with caution in patients with severe hepatic impairment.
Croatian: AZARGU se mora primijeniti s oprezom kod bolesnika s teško oštećenom jetrenom funkcijom.
English: • Do not squeeze the bottle: it is designed so that a gentle press on the bottom is all that it needs
Croatian: • Bočicu nemojte stiskati, ona je izrađena tako da samo trebate pritisnuti njeno dno (slika 2).
English: • Use up one bottle before opening the next bottle.
Croatian: • Prije otvaranja iduće bočice najprije potrošite sadržaj one prethodne.
English: These two components decrease elevated IOP primarily by reducing aqueous humour secretion, but do so by different mechanisms of action.
Croatian: Ta dva sastojka snižavaju povišeni očni tlak prvenstveno smanjenjem lučenja očne vodice, no mehanizmi kojima to čine su različiti.
English: AZARGA should be used with caution in patients with severe hepatic impairment (see section 4.4).
Croatian: AZARGU se mora primijeniti s oprezom kod bolesnika s teško oštećenom jetrenom funkcijom (vidjeti dio 4.4).
English: Beta-blockers may increase the hypoglycaemic effect of antidiabetic agents.
Croatian: Beta-blokatori mogu pojačati hipoglikemijski učinak antidijabetika.
English: Beta-adrenergic blocking medicinal products have been reported to potentiate muscle weakness consistent with certain myasthenic symptoms (e.g. diplopia, ptosis and generalised weakness).
Croatian: Zabilježeno je da beta-adrenergički blokatori mogu potencirati mišićnu slabost koja je u skladu s određenim simptomima mijastenije (e.g. diplopija, ptoza i opća slabost).
English: Non-clinical data reveal no special hazard for humans with timolol based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, and carcinogenic potential.
Croatian: Neklinički podaci timolola ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti i kancerogenog potencijala.
English: Patients must be instructed to remove contact lenses prior to the application of AZARGA and wait 15 minutes after instillation of the dose before reinsertion.
Croatian: Bolesnike se mora uputiti da prije primjene AZARGE izvade kontaktne leće, te da ih ponovno stave 15 minuta nakon primjene kapi.
English: • Sinus bradycardia, sick sinus syndrome, sino-atrial block, second or third degree atrioventricular block not controlled with pace-maker.
Croatian: • Sinus bradikadija, sindrom bolesnoga sinusnog čvora, sinus atrijski blok, atrioventrikularni blok drugog ili trećeg stupnja bez srčanog elektrosimulatora.
English: Due to brinzolamide, electrolyte imbalance, development of an acidotic state, and possibly central nervous system effects may occur.
Croatian: Zbog brinzolamida mogući su disbalans elektrolita, razvoj acidoze i učinci na središnji živčani sustav.
English: Hypoglycaemia/diabetes
Croatian: Hipoglikemija/dijabetes
English: Caution should be utilised in treating these patients and close monitoring of IOP is recommended.
Croatian: Liječenje tih bolesnika mora biti s oprezom, a preporučuje se i pozorno praćenje očnog tlaka.
English: Carbonic anhydrase inhibitors may impair the ability to perform tasks requiring mental alertness and/or physical coordination (see section 4.4).
Croatian: Inhibitori karboanhidraze mogu umanjiti sposobnost obavljanja zadataka koji zahtijevaju mentalnu budnost i/ili fizičku koordinaciju (vidjeti dio 4.4).
English: The cytochrome P-450 isozymes responsible for metabolism of brinzolamide include CYP3A4 (main), CYP2A6, CYP2B6, CYP2C8 and CYP2C9.
Croatian: Među izoenzime citokroma P-450 odgovorne za metabolizam brinzolamida ubrajaju se CYP3A4 (glavni), CYP2A6, CYP2B6, CYP2C8 i CYP2C9.
English: There is a potential for additive effects resulting in hypotension and/or marked bradycardia when an ophthalmic beta-blocker solution is administered concomitantly with oral calcium channel blockers, beta-adrenergic blocking agents, antiarrhythmics (including amiodarone), digitalis glycosides, parasympathomimetics, guanethidine.
Croatian: Mogući su dodatni učinci s posljedičnom hipotenzijom i/ili izraženom bradikardijom kada se otopina beta-blokatora lokalno primijenjena u oko daje istodobno s peroralno primijenjenim blokatorima kalcijevih kanala, beta-adrenergičkim blokatorima, antiaritmicima (uključujući amiodaron), glikozidima digitalisa, parasimpatomimeticima, gvanetidinom.
English: • Reactive airway disease including bronchial asthma or a history of bronchial asthma, or severe chronic obstructive pulmonary disease.
Croatian: • Reaktivne bolesti dišnih putova uključujući bronhalnu astmu ili bronhalna astma u anamnezi ili teška kronična opstruktivna plućna bolest.
English: Tonography and fluorophotometry studies in man suggest that its predominant action is related to reduced aqueous humour formation and a slight increase in outflow facility.
Croatian: Tonografska i fluorofotometrijska ispitivanja pokazuju da je djelovanje pretežno povezano sa smanjenim stvaranjem očne vodice i s blago pojačanim otjecanjem tekućine.
English: When substituting another ophthalmic antiglaucoma medicinal product with AZARGA, the other medicinal product should be discontinued and AZARGA should be started the following day.
Croatian: Kada se drugi očni antiglaukomski lijek zamjenjuje AZARGOM, taj lijek se mora prestati koristiti, a AZARGU početi primjenjivati idući dan.
English: Non-clinical data reveal no special hazard for humans with brinzolamide based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, and carcinogenic potential.
Croatian: Neklinički podaci brinzolamida ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti i kancerogenog potencijala.
English: 3, irritability
Croatian: 3, razdražljivost
English: It is not known whether ophthalmic brinzolamide is excreted in human breast milk.
Croatian: Nije poznato izlučuje li se oftalmički brinzolamid u majčino mlijeko u ljudi.
English: AZARGA contains brinzolamide which is a sulphonamide inhibitor of carbonic anhydrase with systemic absorption.
Croatian: AZARGA sadrži brinzolamid koji je sulfonamidni inhibitor karboanhidraze i sistemski se apsorbira.
English: At steady-state, timolol is detected in human plasma for up to 12 hours after administration of AZARGA.
Croatian: U stanju dinamičke ravnoteže, timolol se u ljudskoj plazmi može dokazati do 12 sati nakon primjene AZARGE.
English: If signs of serious reactions or hypersensitivity occur, discontinue the use of this product and talk to your doctor.
Croatian: Ako se pojave znakovi ozbiljnih reakcija ili preosjetljivosti, prekinite sa primjenom lijeka i obratite se liječniku.
English: • General side effects: decrease in white blood cell count, decreased blood pressure, cough, blood in urine, body weakness.
Croatian: • Opće nuspojave: snižen broj bijelih krvnih zrnaca, snižen krvni tlak, kašalj, krv u mokraći, tjelesna slabost.
English: Oral carbonic anhydrase inhibitors may impair the ability to perform tasks requiring mental alertness and/or physical coordination.
Croatian: Oralni inhibitori karboanhidraze mogu smanjiti sposobnost obavljanja zadataka koji zahtijevaju mentalnu budnost i/ili fizičku koordinaciju.
English: To prevent contamination of the dropper tip and the suspension, care must be taken not to touch the eyelids, surrounding areas or other surfaces with the dropper tip.
Croatian: Da bi se spriječila kontaminacija vrha kapaljke i suspenzije, potrebno je paziti da se vrhom kapaljke ne dotiču vjeđe, okolna područja ili druge površine.
English: • Allergy: increased allergic symptoms, generalised allergic reactions including swelling beneath the skin that can occur in areas such as the face and limbs and can obstruct the airway which may cause difficulty swallowing or breathing, hives, localised and generalised rash, itchiness, severe sudden life-threatening allergic reaction.
Croatian: • Alergija: pojačani simptomi alergije, opće alergijske reakcije uključujući oticanje ispod kože koje se može javiti u području lica i udova a koje mogu začepiti dišne puteve i dovesti do otežanog gutanja ili disanja, koprivnjača, lokalizirani i opći osip, svrbež, iznenadne teške po život opasne alergijske reakcije.