FrancophonIA/ELRC3.0 huggingface dataset:
English: Head and neck region, thoracic space (including the heart and female breast), abdomen (gastrointestinal tract including pancreas), pelvis (prostate, bladder and uterus) and musculoskeletal system
Croatian: Područje glave i vrata, prostor toraksa (uključujući srce i dojke u žena), abdomena (gastrointestinalni trakt uključujući gušteraču), pelvisa (prostata, mokraćni mjehur i maternica) i mišićno-koštani sustav
English: More than one dose should not be used during a scan except for MR cardiac perfusion imaging where two separate doses of 0.05 mmol/kg body weight can be administered in the course of a single examination.
Croatian: Ne smije se primijeniti više od jedne doze tijekom pregleda, osim za MR oslikavanje kardijalne perfuzije gdje se mogu primijeniti dvije zasebne doze od 0.05 mmol/kg tjelesne težine prilikom jedne pretrage.
English: Prior to administration of <Product name>, it is recommended that all patients are screened for renal dysfunction by obtaining laboratory tests.
Croatian: Preporučuje se da se kod svih bolesnika prije primjene <Naziv lijeka> napravi probir za bubrežnu disfunkciju pomoću laboratorijskih testova.
English: This medicinal product is for diagnostic use by intravenous administration only.
Croatian: Ovaj lijek namijenjen je za dijagnostičku uporabu samo putem intravenske primjene.
English: Intravenous gadoteric acid, gadobutrol, gadoteridol Summary of product characteristics
Croatian: Gadoteratna kiselina, gadobutrol, gadoteridol za intravensku primjenu Sažetak opisa svojstava lijeka
English: Brain up to 60 minutes after the administration.
Croatian: Do 60 minuta nakon primjene.
English: With the linear GdCAs this can cause dose-dependent increases in T1-weighted signal intensity in the brain, particularly in the dentate nucleus, globus pallidus, and thalamus.
Croatian: Kod primjene linearnih gadolinijskih kontrastnih sredstava, to može uzrokovati pojačanja intenziteta signala ovisno o dozi na T1-mjerenim snimkama mozga, osobito u nucleus dentatusu, globus pallidusu i talamusu.
English: The recommended dose of <active substance name (INN)> in adult patients and children is 0.05 mmol/kg body weight (0.1 mL/kg of the 0.5 M solution).
Croatian: Preporučena doza <djelatna tvar (INN)> u odraslih bolesnika i djece je 0,05 mmol/kg tjelesne težine (0,1 ml/kg 0,5 molarne otopine).
English: Studies have shown that after exposure to GdCAs gadolinium is retained in the body.
Croatian: Ispitivanja su pokazala da se nakon izlaganja gadolinijskom kontrastnom sredstvu, gadolinij zadržava u tijelu.
English: Breast
Croatian: Dojke
English: Two separate injections of 0.05 mmol/kg body weight (each corresponding to 0.1 mL/kg of the 0.5 M solution) during rest and stress imaging.
Croatian: Dvije zasebne injekcije 0.05 mmol/kg tjelesne težine (svaka odgovara 0,1 ml/kg 0.5 M otopine) za vrijeme oslikavanja pod opterećenjem i u mirovanju.
English: <Active substance name (INN)> is a linear GdCA.
Croatian: <Djelatna tvar (INN)> je linearno gadolinijsko kontrastno sredstvo.
English: 0.05 mmol/kg body weight (0.1 mL/kg of the 0.5 M solution)
Croatian: 0,05 mmol/kg tjelesne težine (0,1 ml/kg 0.5 M otopine)
English: After intravenous administration of <active substance name (INN)> gadolinium can be retained in the brain and in other tissues of the body (bones, liver, kidneys, skin) and can cause dose-dependent increases in T1-weighted signal intensity in the brain , particularly in the dentate nucleus, globus pallidus, and thalamus.
Croatian: Nakon intravenske primjene <djelatna tvar (INN)>, gadolinij se može zadržati u mozgu i drugim tkivima u tijelu (kostima, jetri, bubrezima, koži) i uzrokovati pojačanja intenziteta signala ovisno o dozi na T1-mjerenoj snimci mozga, osobito u nucleus dentatusu, globus pallidusu i talamusu.
English: After administration of <active substance name (INN)> gadolinium can be retained in the brain and in other tissues of the body (bones, liver, kidneys, skin) and can cause dose-dependent increases in T1weighted signal intensity in the brain, particularly in the dentate nucleus, globus pallidus, and thalamus.
Croatian: Nakon primjene <djelatna tvar (INN)>, gadolinij se može zadržati u mozgu i drugim tkivima u tijelu (kostima, jetri, bubrezima, koži) i uzrokovati pojačanja intenziteta signala ovisno o dozi na T1mjerenoj snimci mozga, osobito u nucleus dentatusu, globus pallidusu i talamusu.
English: 0.1 mmol/kg body weight (0.2 mL/kg of the 0.5 M solution)
Croatian: 0,1 mmol/kg tjelesne težine (0,2 ml/kg 0.5 M otopine)
English: <Product name> should be used only when diagnostic information is essential and not available with unenhanced magnetic resonance imaging (MRI) and when delayed phase imaging is required.
Croatian: <Naziv lijeka> se smije primijeniti samo kad su dijagnostičke informacije neophodne i ne mogu se dobiti magnetskom rezonancijom (MR) bez primjene kontrasta i kad su potrebne snimke iz kasne faze.
English: Section 4.1 Therapeutic indications <Product name> should be used only when diagnostic information is essential and not available with unenhanced magnetic resonance imaging (MRI) and when another authorised product cannot be used.
Croatian: Dio 4.1 Terapijske indikacije <Naziv lijeka> se smije primijeniti samo kad su dijagnostičke informacije neophodne i ne mogu se dobiti magnetskom rezonancijom (MR) bez primjene kontrasta i kad se ne može primijeniti drugi odobreni lijek.
English: Section 4.1 Therapeutic indications <Product name> should be used only when diagnostic information is essential and not available with unenhanced magnetic resonance imaging (MRI).
Croatian: Dio 4.1 Terapijske indikacije <Naziv lijeka> se smije primijeniti samo kad su dijagnostičke informacije neophodne i ne mogu se dobiti magnetskom rezonancijom (MR) bez primjene kontrasta.
English: 0.1 mmol/kg body weight, administered as a single bolus of 0.2 mL/kg of the 0.5 M solution.
Croatian: 0,1 mmol/kg tjelesne težine, primijenjene kao jednokratna bolus injekcija od 0,2 ml/kg 0.5 M otopine.
English: Intravenous gadoxetic acid
Croatian: Gadopentetatna kiselina za intraartikularnu primjenu
English: Intra-articular gadoteric acid
Croatian: Gadoteratna kiselina za intraartikularnu primjenu
English: Magnetic resonance angiography
Croatian: MR angiografija
English: Dogs should be carefully monitored.
Croatian: Pse treba pažljivo nadzirati.
English: Children must not come into contact with the product.
Croatian: Djeca ne smiju doći u kontakt s proizvodom.
English: Tablets are available in three different strengths.
Croatian: Tablete su dostupne u tri različite jačine.
English: Do not increase or double the dose.
Croatian: Ne povećavajte i ne udvostručavajte doze.
English: Your veterinarian will advise you if this is the case for your dog.
Croatian: Vaš će vam veterinar savjetovati ako se to odnosi na vašeg psa.
English: Duration of treatment depends on the response to treatment.
Croatian: Trajanje terapije ovisi o reakciji na terapiju.
English: Anaemia (hematocrit)
Croatian: Anaemija (hematokrit)
English: Your veterinarian may need to take blood and urine samples from your dog to perform these checks.
Croatian: Vaš će veterinar možda morati uzeti uzorak krvi i urina vašeg psa kako bi izvršio te preglede.
English: Date of last renewal: 31/07/2014
Croatian: Datum posljednjeg produljenja odobrenja: 31/07/2014
English: Each blister contains 5 tablets.
Croatian: Svaki blister sadrži 5 tableta.
English: Tablets can be administered with or without food.
Croatian: Tablete se mogu davati s hranom ili bez hrane.
English: Each tablet is marked with the strength (10, 15 or 50) on one side, the reverse side is blank.
Croatian: Svaka je tableta označena oznakama jačine (10, 15 ili 50) s jedne strane, druga strana je prazna.
English: The dose should not be <2.2 mg/kg.
Croatian: Doza ne bi trebala biti < 2,2 mg/kg.
English: This will reduce the risk for children or other household members to accidentally come into contact with Palladia.
Croatian: Time ćete smanjiti rizik da će djeca i ostali ukućani slučajno doći u kontakt s Palladijom.
English: Dog Bodyweight (kg)
Croatian: Tjelesna težina psa (kg)
English: ≤1000/ul or neutropenic fever or infection
Croatian: ≤ 1000/ul ili neutropenijska vrućica ili infekcija
English: Toceranib is highly protein bound at between 91% and 93%.
Croatian: Toceranib je visoko vezan na bjelančevine, između 91 % i 93 %.
English: • When you are handling the tablets:
Croatian: • Kada rukujete tabletama:
English: In order to achieve correct dosing, tablets of different strengths (“colours”) might need to be combined as described in the table.
Croatian: Kako bi se postigle pravilne doze, možda će biti potrebno kombinirati tablete različitih jačina (“boja”), kao što je prikazano u tabeli.
English: • Children should not come in contact with Palladia.
Croatian: • Djeca ne smiju doći u kontakt s Palladijom.
English: Località Marino del Tronto 63100 Ascoli Piceno (AP) ITALY
Croatian: Località Marino del Tronto 63100 Ascoli Piceno (AP)
English: • Anyone in your household who administers Palladia to your dog should always wash their hands after handling the tablets.
Croatian: • Svi oni u vašem kućanstvu koji psu daju Palladiju uvijek bi trebali prati ruke nakon rukovanja tabletama.
English: • Hematocrit >25%
Croatian: • Hematokrit > 25 %
English: Maintain dose level
Croatian: Zadržati razinu doze
English: If more than the prescribed amount of tablets were given, contact your veterinarian.
Croatian: Ako ste dali više od propisane količine tableta, obratite se veterinaru.
English: Number of Tablets
Croatian: Broj tableta
English: Hypoalbuminemia (albumin) Albumin <1.5 g/dl
Croatian: Hipoalbuminemija (albumin) Albumin < 1,5 g/dl
English: {Alu-PVC/Blisters}
Croatian: Alu-PVC/blisteri
English: Dose adjustment/reduction:
Croatian: Prilagođavanje/smanjivanje doze:
English: PACKAGE SIZE 20 tablets.
Croatian: VELIČINA PAKOVANJA 20 tableta.
English: No gender differences in pharmacokinetics were observed in-vivo.
Croatian: In-vivo nisu primijećene spolne razlike u farmakokinetici.
English: The blister should always be returned to the cardboard carton once a tablet or tablets have been removed.
Croatian: Blister bi uvijek trebalo vratiti u kartonsku kutiju kada se tableta ili tablete izvade.
English: If the Palladia tablet is “hidden” in food, make sure that your dog has eaten the entire dose.
Croatian: Ako tabletu Palladia “sakrijete” u hranu, neka pas obavezno pojede čitavu dozu.
English: Palladia-treated dogs had a significantly greater objective response rate (37.2 %) compared to dogs treated with placebo (7.9 %).
Croatian: Psi liječeni Palladijom imali su značajno veći postotak objektivne reakcije (37,2 %) u usporedbi s psima koji su primali placebo (7,9 %).
English: Pregnancy, lactation and fertility:
Croatian: Graviditeta, laktacije ili plodnost:
English: Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (http://www.ema.europa.eu/).
Croatian: Detaljne informacije o ovom veterinarsko-medicinskom proizvodu dostupne su na web stranici Europske agencije za lijekove http://www.ema.europa.eu/
English: It is not known to what extent toceranib could affect the elimination of other drugs.
Croatian: Nije poznato u kojoj bi mjeri toceranib mogao utjecati na eliminaciju ostalih lijekova.
English: No interaction studies have been performed with toceranib.
Croatian: Za toceranib nisu provedene studije interakcija.
English: • Creatinine <2.5 mg/dl
Croatian: • Kreatinin < 2,5 mg/dl
English: Dose interruptions and dose reductions may be needed depending upon the severity of clinical signs.
Croatian: Prekid i smanjenje doze mogu biti potrebni u ovisnosti o težini kliničkih simptoma.
English: After 6 weeks of treatment, a complete response was noted for 8.1 % and partial response was noted for 29.1 % of dogs treated with Palladia.
Croatian: Nakon šest tjedana terapije kompletna reakcija zabilježena je na 8,1 %, a djelomična reakcija na 29,1 % pasa liječenih Palladijom.
English: If a dose is missed, the next schedule dose should be given as prescribed.
Croatian: Ako se propusti doza, sljedeću dozu treba dati kako je prepisano.
English: Treatment should continue in the case of stable disease, or partial or complete response, provided that the product is sufficiently well tolerated.
Croatian: Terapiju treba nastaviti u slučaju stabilizacije bolesti, ili djelomične ili potpune reakcije, pod uvjetom da životinja zadovoljavajuće podnosi proizvod.
English: In case of tumour progression, treatment is unlikely to be successful and should be reviewed.
Croatian: U slučaju progresije tumora terapija vjerojatno neće biti uspješna i treba je ponovo razmotriti.
English: There are some medicines that you should not give to your dog during treatment because together, they might cause serious adverse effects.
Croatian: Neke lijekove ne biste smjeli davati psu tijekom terapije jer oni zajedno s ovim lijekom mogu uzrokovati ozbiljne nuspojave.
English: Discontinue treatment until clinical signs and clinical pathology have normalised.
Croatian: Prekinite terapiju dok se klinički simptomi i klinička patologija ne normaliziraju.
English: Dose Adjustment*
Croatian: Prilagodba doze*
English: Therefore, the dosage given should be as described by your veterinarian, even if this is different from the dosing table.
Croatian: Stoga, morate davati onu dozu koju je prepisao veterinar, čak i ako se razlikuje od doze iz tabele za doziranje.
English: Severe:
Croatian: Teške:
English: Do not break or grind the tablets.
Croatian: Ne prelamajte i ne meljite tablete.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 23/09/2009
Croatian: Datum prvog odobrenja: 23/09/2009
English: Do not use this veterinary medicinal product after the expiry date which is stated on the carton after “EXP”.
Croatian: Ne koristite veterinarsko-medicinski proizvod poslije isteka roka valjanosti naznačenog na kutiji poslije EXP.
English: Do not use in dogs with gastrointestinal bleeding.
Croatian: Ne davati psima s gastrointestinalnim krvarenjem.
English: Periodic monitoring of laboratory variables should be completed in the context of the clinical signs and condition of the animal and results of laboratory variables at prior visits.
Croatian: Periodičko praćenje laboratorijskih varijabli trebalo bi biti usklađeno s kliničkim simptomima i stanjem životinje te rezultatima laboratorijskih varijabli na prethodnim kontrolama.
English: As angiogenesis is a critical component of embryonic and foetal development, inhibition of angiogenesis following administration of Palladia should be expected to result in adverse effects on the pregnancy in the bitch.
Croatian: Budući da je angiogeneza kritična komponenta embrionalnog i fetalnog razvoja, treba očekivati da će inhibicija angiogeneze nakon primjene Palladije uzrokovati nuspojave u trudnoći kuje.
English: If you notice any side effects, even those not already listed in this package leaflet or you think that the medicine has not worked, please inform your veterinary surgeon.
Croatian: Ako zamijetite bilo koju nuspojavu ili druge nuspojave koje nisu opisane u uputi o VMP, ili smatrate da lijek nije djelovao, molimo obavijestite svog veterinara.
English: • Severe circulatory shock
Croatian: • Teški cirkulatorni šok
English: The field study comprised a 6-week double-blind placebo controlled phase followed by an un-blinded phase where all dogs received Palladia for a mean duration of 144 days.
Croatian: Studija je uključivala šestotjednu, dvostruko slijepu placebo-kontroliranu fazu nakon koje je slijedila neslijepa faza u kojoj su svi psi dobivali Palladiju u prosječnom trajanju od 144 dana.
English: • Severe circulatory shock.
Croatian: • Teški cirkulatorni šok.
English: • If Palladia is accidentally ingested (swallowed or eaten) by you or a family member, seek medical advice immediately.
Croatian: • Ako vi ili član vaše obitelji slučajno uzmete (progutate ili pojedete) Palladiju, odmah potražite savjet liječnika.
English: *A 0.5 mg/kg dose decrease is a decrease from 3.25 mg/kg to 2.75 mg/kg or from 2.75 mg/kg to 2.25 mg/kg.
Croatian: *Smanjivanje doze od 0,5 mg/kg jest smanjivanje s 3,25 mg/kg na 2,75 mg/kg ili s 2,75 mg/kg na 2,25 mg/kg.
English: See sections 4.4, 4.5 and 4.9 for Dose Adjustment Guidelines.
Croatian: Smjernice za prilagodbu doze potražite u odjeljcima 4.4, 4.5 i 4.9.
English: Palladia are round tablets and have a coloured film coat to minimise risk of exposure and to help identify the correct tablet strength.
Croatian: Palladia su okrugle filmom obložene tablete u boji kako bi se maksimalno umanjila opasnost od izlaganja i pomoglo u identifikaciji prave jačine tablete.
English: THE WORDS “FOR ANIMAL TREATMENT ONLY” AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE, IF APPLICABLE
Croatian: 13. RIJEČI “SAMO ZA PRIMJENU NA ŽIVOTINJAMA” I UVIJETI ILI OGRANIČENJA U POGLEDU OPSKRBE I PRIMJENE, ako je primjenjivo
English: The following handling procedures will help to minimise exposure to the active ingredient in Palladia for you and other members of your household:
Croatian: Sljedeći postupak rukovanja pomoći će pri smanjivanju izloženosti vas i vaših ukućana djelatnom sastojku Palladije:
English: Pharmacotherapeutic group: Antineoplastic Agents - Protein-kinase inhibitors ATC vet code: QL01XE91
Croatian: Farmakoterapijska grupa: antineoplastične tvari -inibitori protein-kinaze ATCvet kod: QL01XE91
English: Neutropenia (neutrophil count) >1000/ul
Croatian: Neutropenija (broj neutrofila) > 1000/ul
English: Some dogs may also show a loss of colour around their nose, some dogs may show a change in coat colour which appears to lighten and some dogs may lose hair.
Croatian: Kod nekih se pasa može javiti depigmentacija u području nosa, promjena boje dlake, koja može posvijetliti, a neki psi mogu izgubiti dlaku.
English: Results from the clinical field study involving 151 treated and placebo-treated dogs showed that the clinical signs of the disease (mast cell tumour) and treatment related adverse reactions are very similar in nature.
Croatian: Rezultati kliničke studije koja je uključivala 151 psa liječenog lijekom i placebom pokazali su da su klinički simptomi bolesti (tumor mastocita) i nuspojave povezane s terapijom vrlo slične prirode.
English: Following oral administration of toceranib phosphate, approximately 92% of the administered drug is excreted in faeces with another 7% excreted in urine.
Croatian: Nakon peroralne primjene toceranib fosfata približno 92 % unesenog lijeka izlučuje se u stolici, a još 7 % u urinu.
English: Tell your veterinarian about all medicines, including overthe-counter products, that you intend to administer to your dog.
Croatian: Obavijestite veterinara o svim lijekovima, uključujući i one koji su dostupni bez recepta, koje namjeravate dati svojem psu.
English: Ingestion of Palladia may be harmful for children.
Croatian: Gutanje Palladije može štetiti djeci.
English: There are no in vivo data on the hepatic metabolism in dogs.
Croatian: Ne postoje in vivo podaci o jetrenom metabolizmu kod pasa.
English: DATE ON WHICH THE PACKAGE LEAFLET WAS LAST APPROVED Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (http://www.ema.europa.eu/).
Croatian: 14. DATUM POSLJEDNJEG ODOBRENJA UPUTE O VMP Detaljne informacije o ovom veterinarsko-medicinskom proizvodu su dostupne na web stranici Europske agencije za lijekove http://www.ema.europa.eu/.
English: Do not use in dogs less than 2 years of age or less than 3 kg bodyweight.
Croatian: Ne davati psima mlađima od dvije godine ili lakšima od 3 kg.
English: Dose Adjustment Based on Clinical Signs / Pathology Clinical signs / pathology
Croatian: Prilagodba doze na temelju kliničkih simptoma/patologije
English: Mild to moderate:
Croatian: Blage do umjerene:
English: Use non-steroidal anti-inflammatory drugs with caution in conjunction with Palladia due to an increased risk of gastrointestinal ulceration or perforation.
Croatian: Oprezno upotrebljavajte nesteroidne protuupalne lijekove u kombinaciji s Palladijom zbog povećane opasnosti od gastrointestinalne ulceracije ili perforacije.
English: With a regimen of 3.25 mg toceranib/kg bodyweight administered by tablet orally every other day for 2 weeks (7 doses), the following pharmacokinetic parameters of toceranib in plasma in healthy Beagle dogs were reported: elimination half-life (t1/2) 17.2 ± 3.9 hours, time to maximum plasma concentration (Tmax) approximately 6.2 ± 2.6 hours, maximum plasma concentration (Cmax) approximately 108 ± 41 ng/ml, minimum plasma concentration (Cmin) 18.7 ± 8.3 ng/ml and the area under the plasma concentration time-curve (AUC0-48) 2640 ± 940 ng·h/ml.
Croatian: U režimu od 3,25 mg toceraniba na kilogram tjelesne težine koji se primjenjuje peroralno tabletama svakog drugog dana tijekom 2 tjedna (7 doza), prijavljeni su sljedeći farmakokinetički parametri toceraniba u plazmi zdravih pasa pasmine beagle: poluživot eliminacije (t1/2) 17,2 ± 3,9 sati, vrijeme do maksimalne koncentracije plazme (Tmax) približno 6,2 ± 2,6 sati, maksimalna koncentracija plazme (Cmax) približno 108 ± 41 ng/ml, minimalna koncentracija plazme (Cmin) 18,7 ± 8,3 ng/ml i područje pod vremenskom krivuljom koncentracije plazme (AUC0-48) 2640 ± 940 ng·h/ml.
English: As toceranib is likely eliminated to a large extent by metabolism in the liver, the combination with other drugs capable of inducing or inhibiting liver enzymes should be used with caution.
Croatian: Budući da se toceranib vjerojatno u velikoj mjeri eliminira metabolizmom u jetrima, ostale lijekove koji mogu inducirati ili inhibirati jetrene enzime treba kombinirati oprezno.
English: Before performing surgery, discontinue treatment for at least 3 days in order to assure vasculature homeostasis.
Croatian: Prekinite terapiju barem tri dana prije operacije kako bi se osigurala vaskularna homeostaza.
English: Linear pharmacokinetics were seen irrespective of the route of administration at doses up to 5 mg/kg given twice daily.
Croatian: Linearna farmakokinetika uočena je bez obzira na način unošenja, u dozama do 5 mg/kg davanim dvaput dnevno.
English: Anorexia <50% food intake ≥2 days
Croatian: Anoreksija < 50 % unosa hrane ≥ 2 dana
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE Cardboard Carton/tablets
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKOVANJU Kartonska kutija/tablete
English: The dose given should be based on veterinary assessments conducted weekly for the first six weeks and, thereafter, every six weeks.
Croatian: Doza bi se trebala temeljiti na procjeni veterinara, procijenjenu dozu trebalo bi davati jednom tjedno prvih šest tjedana, a nakon toga svakih šest tjedana.
English: THE WORDS “KEEP OUT OF THE SIGHT AND REACH OF CHILDREN” Keep out of the sight and reach of children.
Croatian: I POGLEDA DJECE” Držati izvan pogleda i dosega djece.
English: Anaemia and neutropaenia and eosinopaenia were doserelated.
Croatian: Anemija, neutropenija i eozinopenija bile su povezane s doziranjem.
English: The main target organs of toxicity include the gastrointestinal tract, bone marrow, gonads and musculoskeletal system.
Croatian: Glavni organi pogođeni toksičnošću uključuju gastrointestinalni trakt, koštanu srž, gonade i mišićnokoštani sustav.
English: Toceranib exerts an antiproliferative effect on endothelial cells in-vitro.
Croatian: Toceranib ima antiproliferacijski učinak na endotelne stanice in-vitro.
English: • Absolute neutrophil count >1500/microlitre
Croatian: • Apsolutni broj neutrofila > 1500/mikrolitra
English: Gastrointestinal Bleeding Fresh blood in stool or black tarry stool for >2 days or frank haemorrhage or blood clots in stool
Croatian: Svježa krv u stolici ili crna katranasta stolica > 2 dana ili očito krvarenje ili krvni ugrušci u stolici
English: There was also a significant advantage of Palladia over placebo in the secondary efficacy endpoint, time to tumour progression.
Croatian: Zabilježena je i značajna prednost Palladije pred placebom u napredovanju tumora u vremenu sekundarne krajnje točke učinkovitosti.