FrancophonIA/ELRC3.0 huggingface dataset:
English: Accidental self-injection can result in clinical signs of low blood glucose levels which can be treated by taking sugar by mouth.
Slovenian: Nenamerno samoinjiciranje lahko povzroči klinične znake nizkih ravni glukoze v krvi, kar je mogoče odpraviti z peroralnim zaužitjem sladkorja.
English: ProZinc is an insulin to which protamine and zinc have been added to create crystals.
Slovenian: Zdravilo Prozinc je insulin, ki sta mu bila dodana protamin in cink, da se ustvarijo kristali.
English: How is ProZinc used?
Slovenian: Kako se zdravilo ProZinc uporablja?
English: In a field study involving 139 diabetic cats of various ages and breeds, after 6 weeks of treatment with ProZinc average blood sugar levels decreased and clinical signs improved, for example average body weight increased; 116 out of 139 cats (84%) were considered to be treated successfully.
Slovenian: V terenski študiji, ki je vključevala 139 mačk s sladkorno boleznijo različnih starosti in pasem, so se po šestih tednih zdravljenja z zdravilom ProZinc povprečne ravni krvnega sladkorja znižale, klinični znaki
English: How does ProZinc work?
Slovenian: Kako zdravilo ProZinc deluje?
English: It should not usually be used on more than one occasion in any one patient.
Slovenian: Navadno se zdravila pri posameznem bolniku ne sme uporabiti več kot enkrat.
English: The marketing authorisation was renewed on 29 November 2005.
Slovenian: Dovoljenje za promet z zdravilom je bilo podaljšano 29. novembra 2005.
English: The marketing authorisation holder is CIS bio international.
Slovenian: Imetnik dovoljenja za promet z zdravilom je družba CIS bio international.
English: Medicinal product no longer authorise©EMEA 2007
Slovenian: ©EMEA 2007
English: EUROPEAN PUBLIC ASSESSMENT REPORT (EPAR) NEOSPECT
Slovenian: EVROPSKO JAVNO POROČILO O OCENI ZDRAVILA (EPAR) NEOSPECT
English: This means that it acts like somatostatin, and binds to the same receptors as somatostatin in the body.
Slovenian: To pomeni, da deluje podobno kot somatostatin in se v telesu veže na iste receptorje kot somatostatin.
English: The European Commission granted a marketing authorisation valid throughout the European Union for NeoSpect on 29 November 2000.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom NeoSpect, veljavno po vsej Evropski uniji, odobrila dne 29. novembra 2000.
English: What is the risk associated with NeoSpect?
Slovenian: Kakšna tveganja so povezana z zdravilom NeoSpect?
English: These receptors are found in large numbers on some malignant tumours such as lung tumours.
Slovenian: Ti receptorji so množično prisotni na nekaterih malignih tumorjih, kot npr. na pljučnih tumorjih.
English: The main measure of effectiveness was the accuracy of diagnosing a malignant tumour (positive) or a benign tumour (negative).
Slovenian: Glavno merilo učinkovitosti je bila pravilnost diagnosticiranja malignega tumorja (pozitivna vrednost) ali benignega tumorja (negativna vrednost).
English: NeoSpect should not be used in women who are pregnant
Slovenian: Zdravila NeoSpect ne smejo uporabljati ženske, ki so noseče ali dojijo.
English: NeoSpect has been studied in two main trials involving 258 patients with suspected lung cancer.
Slovenian: Zdravilo NeoSpect so preučevali v dveh glavnih preizkušanjih, ki sta vključevali 258 bolnikov s sumom na pljučni rak.
English: NeoSpect is only handled and given by specialised personnel who have experience in the safe handling of radioactive material.
Slovenian: Z zdravilom NeoSpect smejo rokovati in ga dajati le strokovno usposobljene osebe, ki imajo izkušnje z varnim rokovanjem z radioaktivnimi snovmi.
English: What benefit has NeoSpect shown during the studies?
Slovenian: Kakšne koristi je zdravilo NeoSpect izkazalo med raziskavami?
English: NeoSpect is not used on its own, but it must be radiolabelled before use.
Slovenian: Zdravilo NeoSpect se ne uporablja samostojno, temveč ga je treba pred uporabo radioaktivno označiti.
English: The Committee recommended that NeoSpect be given marketing authorisation.
Slovenian: Odbor je zato priporočil, da se za zdravilo NeoSpect odobri dovoljenje za promet z zdravilom.
English: How has NeoSpect been studied?
Slovenian: Kako je bilo zdravilo NeoSpect raziskano?
English: The radiolabelled medicine is for diagnostic use.
Slovenian: Radioaktivno označeno zdravilo se uporablja za diagnostične namene.
English: Side effects with NeoSpect are uncommon, but the most common (seen in between 1 and 10 patients in 1000) are headache, nausea (feeling sick), vomiting, diarrhoea, abdominal (tummy) pain, dizziness, flushing and fatigue (tiredness).
Slovenian: Neželeni učinki zdravila NeoSpect so občasni, vendar pa so najpogostejši (opaženi pri 1 do 10 bolnikih izmed 1000) glavobol, navzeja (slabost), bruhanje, driska, bolečine v trebuhu, omotica,
English: NeoSpect should not be used in people who may be hypersensitive (allergic) to depreotide, sodium pertechnetate or any of the other ingredients.
Slovenian: Zdravila NeoSpect se ne sme uporabljati pri osebah, ki utegnejo biti preobčutljive za (alergične na) depreotid, natrijev pertehnetat ali katerokoli drugo sestavino zdravila.
English: When NeoSpect is radiolabelled, the radioactive element technetium-99m (99mTc) is attached to depreotide.
Slovenian: Z radioaktivno označitvijo zdravila NeoSpect se radioaktivni element tehnecij-99m (99mTc) veže na depreotid.
English: As depreotide binds to the receptors, it carries the radioactivity with it, and this can be detected using special imaging equipment, such as scintigraphy or single photon emission computed tomography (SPECT).
Slovenian: Ko se depreotid veže na receptorje, s seboj prinese tudi radioaktivnost, to pa je mogoče odkriti s posebno opremo za slikanje, kot je scintigrafija ali računalniška tomografija emisije posameznih fotonov (SPECT).
English: If it is not, then it is likely to
Slovenian: Če ga ne označi, je le-ta verjetno benigen (nemaligen).
English: Once made up into a radiolabelled solution, NeoSpect is given by intravenous injection (into a vein), and a scan is taken two to four hours after the injection.
Slovenian: Ko se zdravilo NeoSpect pripravi v obliki radioaktivno označene raztopine, ga vbrizgamo z intravensko injekcijo (v veno), slikanje pa se izvede dve do štiri ure po injiciranju.
English: The result of the NeoSpect scan was in agreement with the result obtained by histology in between 80 and 90% of the cases.
Slovenian: Rezultat slikanja z uporabo zdravila NeoSpect se je v 80 do 90 % primerov ujemal z rezultatom, dobljenim s histološko preiskavo.
English: Radiolabelling is a technique where a substance is tagged (labelled) with a radioactive compound.
Slovenian: Radioaktivno označevanje je tehnika, pri kateri se učinkovino označi z radioaktivno spojino.
English: The active substance in NeoSpect, depreotide, is a somatostatin analogue.
Slovenian: Zdravilna učinkovina zdravila NeoSpect, depreotid, je analog somatostatina.
English: The Committee for Medicinal products for Human Use (CHMP) decided that NeoSpect's benefits are greater than its risks for the scintigraphic imaging of suspected malignant lung tumours in the lung after initial detection, in combination with CT scan or chest X-ray, in patients with solitary pulmonary nodules.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) je odločil, da so koristi zdravila NeoSpect pri scintigrafskem slikanju pljučnih tumorjev s sumom na malignost po začetnem odkritju v kombinaciji z računalniško tomografijo (CT) ali rentgenskim slikanjem prsnega koša pri bolnikih s posameznimi vozliči v pljučih večje od z njim povezanih tveganj.
English: NeoSpect includes a white powder for solution for injection, which contains the active substance depreotide.
Slovenian: Zdravilo NeoSpect vsebuje bel prašek za pripravo raztopine za injiciranje, ki vsebuje zdravilno učinkovino depreotid.
English: If the solitary pulmonary nodule is labelled with NeoSpect, it is likely to be malignant.
Slovenian: Če zdravilo NeoSpect označi posamezni pljučni vozlič, je le-ta verjetno maligen.
English: NeoSpect is radiolabelled by mixing it with a solution of radioactive technetium (99mTc).
Slovenian: Zdravilo NeoSpect se radioaktivno označi tako, da ga zmešamo z raztopino radioaktivnega tehnecija (99mTc).
English: Adding a NeoSpect scan to a CT scan increased the specificity of the scan, making it easier for the doctor to identify a nodule as malignant.
Slovenian: Dodajanje slikanja z uporabo zdravila NeoScan k računalniški tomografiji (CT) je povečalo specifičnost slikanja in zdravniku olajšalo ugotavljanje malignosti
English: The full EPAR for NeoSpect is available here.
Slovenian: Celotno Evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo NeoSpect je na voljo tukaj.
English: NeoSpect is used in patients who have a single pulmonary nodule (a small, round lesion in the lungs) detected by a chest X-ray or computerised tomography (CT) scan to see if the nodule is malignant (cancerous).
Slovenian: Zdravilo NeoSpect se uporablja pri bolnikih s posameznim vozličem v pljučih (majhno okroglo lezijo v pljučih), ki je bila odkrita z rentgenskim slikanjem prsnega koša ali računalniško tomografijo (CT), da bi ugotovili, ali je vozlič
English: NeoSpect is a kit for preparing a radiolabelled medicine.
Slovenian: Zdravilo NeoSpect je komplet za pripravo radioaktivno označenega zdravila.
English: The outcome of the NeoSpect scan was compared to the actual diagnosis, based on the histology of the
Slovenian: Rezultate slikanja z uporabo zdravila NeoSpect so primerjali z dejansko diagnozo na podlagi histološke preiskave vozliča (pri kateri se tkivo operativno odstranjenega vozliča analizira pod mikroskopom).
English: The patients underwent a chest X-ray or a CT scan as well as a SPECT scan using radiolabelled NeoSpect.
Slovenian: Pri bolnikih so izvedli rentgensko slikanje prsnega koša ali računalniško
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 16 November 2015
Slovenian: Datum prve odobritve: 16 november 2015
English: Try to take Aripiprazole Accord at the same time each day.
Slovenian: Prizadevajte si vzeti zdravilo Aripiprazol Accord vsak dan ob istem času.
English: Consequently, the frequency of these adverse events is qualified as “not known”
Slovenian: Zato je pogostnost teh neželenih učinkov opredeljena kot »neznana«.
English: This should be considered in cases where full alertness is required, e.g. when driving a car or handling machines.
Slovenian: To je treba upoštevati, ko je potrebna popolna zbranost, npr. pri vožnji avtomobila ali upravljanju strojev.
English: Even if you feel better, do not alter or discontinue the daily dose of this medicine without first consulting your doctor.
Slovenian: Tudi če se počutite bolje, ne spreminjajte dnevnega odmerka in ne nehajte jemati tega zdravila, ne da bi se prej posvetovali z zdravnikom.
English: • binge eating (eating large amounts of food in a short time period) or compulsive eating (eating more food than normal and more than is needed to satisfy your hunger)
Slovenian: - prenajedanje (uživanje velikih količin hrane v kratkem obdobju) ali kompulzivno uživanje hrane (uživanje večjih količin hrane od normalnih in več, kot je potrebno za potešitev lakote),
English: Sage house, 319 Pinner road, North Harrow, Middlesex HA1 4HF, United Kingdom
Slovenian: Sage house, 319 Pinner road, North Harrow, Middlesex HA1 4HF, Velika Britanija
English: Blood pressure-lowering medicines: Aripiprazole Accord may increase the effect of medicines used to lower the blood pressure.
Slovenian: Zdravila za zniževanje krvnega tlaka: zdravilo Aripiprazol Accord lahko okrepi učinek zdravil, ki se uporabljajo za zniževanje krvnega tlaka.
English: In adults it also prevents this condition from returning in patients who have responded to the treatment with this medicine.
Slovenian: Zdravilo tudi preprečuje ponovitve bolezni pri odraslih bolnikih, ki so se odzvali na zdravljenje s tem zdravilom.
English: • rapid heartbeat, agitation/aggressiveness, problems with speech.
Slovenian: • hitro bitje srca, vznemirjenost/agresivnost, težave pri govoru;
English: If you miss a dose, take the missed dose as soon as you remember but do not take two doses in one day.
Slovenian: Če ste pozabili vzeti zdravilo Aripiprazol Accord Če ste pozabili vzeti odmerek, ga vzemite takoj, ko se spomnite, vendar ne vzemite dveh odmerkov na en dan.
English: • altered or increased sexual interest and behaviour of significant concern to you or to others, for example, an increased sexual drive
Slovenian: - spremenjeno ali povečano spolno zanimanje in vedenje, ki vam ali drugim povzroča znatno zaskrbljenost, na primer povečan libido,
English: Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non genotoxic.
Slovenian: Na podlagi celotnega spektra standardnih preskusov genotoksičnosti je bilo ocenjeno, da aripiprazol ni genotoksičen.
English: Prolactin levels were evaluated in all trials of all doses of aripiprazole (n = 28,242).
Slovenian: V vseh preizkušanjih so ocenili raven vseh odmerkov prolaktina (n = 28.242).
English: 14 x 1 tablets 28 x 1 tablets 49 x 1 tablets 56 x 1 tablets 98 x 1 tablets
Slovenian: 14 x 1 tableta 28 x 1 tableta 49 x 1 tableta 56 x 1 tableta 98 x 1 tableta
English: It is important that you carry on taking Aripiprazole Accord for as long as your doctor has told you to.
Slovenian: Pomembno je, da zdravljenje z zdravilom Aripiprazol Accord nadaljujete tako dolgo, kot vam je svetoval zdravnik.
English: The point estimate of the hazard ratio (HR) was 0.461 (95% confidence interval, 0.242-0.879) in the full population.
Slovenian: Ocenjena vrednost razmerja ogroženosti (RO) je bila 0,461 (95-% interval zaupanja, 0,242-0,879) pri celotni poulaciji.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with aripiprazole in one or more subsets of the paediatric population in the treatment of schizophrenia and in the treatment of bipolar affective disorder (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z zdravilom Aripiprazol Accord za eno ali več podskupin pediatrične populacije pri zdravljenju shizofrenije in bipolarne afektivne motnje (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: However, the estimation of the HR for the younger (13-14 years) group was not precise, reflecting the smaller number of subjects in that group (aripiprazole, n = 29; placebo, n = 12), and the confidence interval for this estimation (ranging from 0.151 to 1.628) did not allow conclusions to be drawn on the presence of a treatment effect.
Slovenian: Vendar pa ocena razmerja ogroženosti pri skupini mlajših mladostnikov (13-14 let) ni bila točna zaradi manjšega števila preskušancev v tej skupini (aripiprazol, n = 29; placebo, n = 12), interval zaupanja za to oceno (ki je od 0,151 do 1,628) pa ne omogoča zaključkov o prisotnosti učinka zdravljenja.
English: Patients with rare hereditary problems of galactose intolerance, the lapp lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Slovenian: Bolniki z redko dedno intoleranco za galaktozo, laponsko obliko zmanjšane aktivnosti laktaze ali malabsorpcijo glukoze/galaktoze ne smejo jemati tega zdravila.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
Slovenian: Druga zdravila in zdravilo Aripiprazol Accord Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo, vključno z zdravili, ki ste jih dobili brez recepta.
English: Aripiprazole Accord contains the active substance aripiprazole and belongs to a group of medicines called antipsychotics.
Slovenian: Zdravilo Aripiprazol Accord vsebuje zdravilno učinkovino aripiprazol in spada v skupino zdravil, imenovanih antipsihotiki.
English: If you have the impression that the effect of this medicine is too strong or too weak, talk to your doctor or pharmacist.
Slovenian: Če menite, da je učinek tega zdravila premočan ali prešibak, se posvetujte z zdravnikom ali s farmacevtom.
English: Taking ARIPIPRAZOLE ACCORD with some medicines may mean the doctor will need to change your dose of ARIPIPRAZOLE ACCORD or the other medicines.
Slovenian: Če jemljete zdravilo Aripiprazol Accord z nekaterimi drugimi zdravili, bo morda zdravnik moral spremeniti vaš odmerek zdravila Aripiprazol Accord ali drugih zdravil.
English: Wessling Hungary, Anonymus u. 6., Budapest, 1045, Hungary
Slovenian: Wessling Hungary, Anonymus u. 6., Budapest, 1045, Madžarska
English: What Aripiprazole Accord is and what it is used for
Slovenian: Kaj je zdravilo Aripiprazol Accord in za kaj ga uporabljamo
English: Do not use this medicine after the expiry date which is stated on the blister or label and on the carton after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na pretisnem omotu ali nalepki in na škatli poleg oznake “EXP:” ali “Uporabno do:”.
English: Therefore, Aripiprazole Accord is not recommended for use in patients below 13 years of age (see sections 4.8 and 5.1).
Slovenian: Uporabe zdravila Aripiprazol Accord se zato pri bolnikih, mlajših od 13 let, ne priporoča (glejte poglavji 4.8 in 5.1).
English: Extrapyramidal symptoms were mainly reported during the stabilisation phase in 17 % of patients, with tremor accounting for 6.5 %.
Slovenian: O ekstrapiramidnih simptomih so poročali predvsem med stabilizacijsko fazo, in sicer pri 17 % bolnikov, od tega je 6,5 % predstavljal tremor.
English: • strong impulse to gamble excessively despite serious personal or family consequences
Slovenian: - močna želja po čezmernem hazardiranju ne glede na posledice za vas ali za družino,
English: • acute confusion, seizures (epilepsy), coma, a combination of fever, faster breathing, sweating,
Slovenian: • akutno zmedenost, krče (epilepsijo), komo, kombinacijo zvišane telesne temperature, hitrega dihanja, znojenja;
English: Increased mortality
Slovenian: Povečanje telesne mase
English: Patients treated with any antipsychotics, including aripiprazole, should be observed for signs and symptoms of hyperglycaemia (such as polydipsia, polyuria, polyphagia and weakness) and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control (see section 4.8).
Slovenian: Bolnike, ki dobivajo kateri koli antipsihotik, vključno z aripiprazolom, je treba opazovati glede znakov in simptomov hiperglikemije (npr. polidipsije, poliurije, polifagije in šibkosti); bolnike z diabetesom mellitusom ali dejavniki tveganja zanj pa je treba redno nadzirati, da bi odkrili poslabšanje urejenosti glukoze (glejte poglavje 4.8) .
English: Aripiprazole has minor to moderate influence on the ability to drive and use machines due to potential nervous system and visual effects, such as sedation, somnolence, syncope, vision blurred, diplopia (see section 4.8).
Slovenian: Aripiprazol ima blag do zmeren vpliv na sposobnost vožnje in upravljanja s stroji zaradi morebitnega vpliva na živčni sistem in vid, kot je sedacija, somnolenca, sinkopa, zamegljen vid in diplopija (glejte poglavje 4.8).
English: CARTON FOR BOTTLE AND BOTTLE LABEL
Slovenian: ŠKATLA ZA VSEBNIK IN NALEPKA
English: Developmentaltoxicity, including dose-dependent delayed foetal ossification and possible teratogenic effects, were observed in rats at doses resulting in subtherapeutic exposures (based on AUC) and in rabbits at doses resulting in exposures 3 and 11 times the mean steady-state AUC at the maximum recommended clinical dose.
Slovenian: Razvojne toksične učinke, vključno z od odmerka odvisno zapoznelo fetalno osifikacijo in možnimi teratogenimi učinki, so pri podganah opažali v odmerkih, ki so povzročili subterapevtsko izpostavljenost (na podlagi AUC), in pri kuncih v odmerkih, ki so povzročili izpostavljenost 3- in 11kratne srednje AUC v stanju dinamičnega ravnovesja ob največjem priporočenem kliničnem odmerku.
English: Aripiprazole Accord is indicated for the treatment of schizophrenia in adults and in adolescents aged 15 years and older.
Slovenian: Zdravilo Aripiprazol Accord je indicirano za zdravljenje shizofrenije pri odraslih in mladostnikih, starih 15 let in več.
English: Aripiprazole Accord is effective in a dose range of 10 to 30 mg/day.
Slovenian: Aripiprazol je učinkovit v razponu odmerkov od 10 do 30 mg/dan.
English: Medicines that increase the level of serotonin are typically used in conditions including depression, generalised anxiety disorder, obsessive-compulsive disorder (OCD) and social phobia as well as migraine and pain:
Slovenian: Zdravila, ki povečajo raven serotonina, navadno uporabljamo za bolezni, ki vključujejo depresijo, generalizirano anksiozno motnjo, obsesivno-kompulzivno motnjo (OCD- obsessive compulsive disorder) in socialno fobijo, kot tudi za migrene in bolečine:
English: If you realise you have taken more Aripiprazole Accord than your doctor has recommended (or if someone else has taken some of your Aripiprazole Accord), contact your doctor right away.
Slovenian: Če ste vzeli večji odmerek zdravila Aripiprazol Accord, kot bi smeli Če ugotovite, da ste vzeli več zdravila Aripiprazol Accord, kot vam je priporočil zdravnik (ali če je vaše zdravilo Aripiprazol Accord vzel kdo drug), se takoj posvetujte s svojim zdravnikom.
English: Irritability associated with autistic disorder: the safety and efficacy of Aripiprazole Accord in children and adolescents aged below 18 years have not yet been established.
Slovenian: Razdražljivost, povezana z avtistično motnjo: varnost in učinkovitost zdravila Aripiprazol Accord pri otrocih in mladostnikih, mlajših od 18 let, še nista bili dokazani.
English: The safety and efficacy of Aripiprazole Accord in the treatment of schizophrenia or manic episodes inBipolar I Disorder in patients aged 65 years and older has not been established.
Slovenian: Varnost in učinkovitost zdravila Aripiprazol Accord nista ugotovljeni pri zdravljenju shizofrenije ali maničnih epizod bipolarne motnje I pri bolnikih, starih 65 let in starejših.
English: Concomitant administration of aripiprazole and other stronginducers of CYP3A4 (such as rifampicin, rifabutin, phenytoin, phenobarbital, primidone, efavirenz, nevirapine and St. John's Wort) may be expected to have similar effects and similar dose increases should therefore be applied.
Slovenian: Pri sočasni uporabi aripiprazola in drugih induktorjev CYP3A4 (npr. rifampicin, rifabutin, fenitoin, fenobarbital, primidon, efavirenz, nevirapin in šentjanževka) je mogoče pričakovati, da imajo podobne učinke, zato je treba odmerjanje podobno zvečati.
English: It has been proposed that aripiprazole's efficacy in schizophrenia and Bipolar I Disorder is mediated through a combination of partial agonism at dopamine D2 and serotonin 5HT1a receptors and antagonism of serotonin 5HT2a receptors.
Slovenian: Učinkovitost aripiprazola pri shizofreniji in bipolarni motnji I je domnevno posledica kombinacije delnega agonizma na dopaminskih receptorjih D2 in serotoninskih receptorjih 5-HT1a ter antagonizma na serotoninskih receptorjih 5-HT2a.
English: What Aripiprazole Accord is and what it is used for What you need to know before you take Aripiprazole Accord How to take Aripiprazole Accord Possible side effects 5 How to store Aripiprazole Accord Contents of the pack and other information
Slovenian: Kaj je zdravilo Aripiprazol Accord in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Aripiprazol Accord Kako jemati zdravilo Aripiprazol Accord Možni neželeni učinki