FrancophonIA/ELRC3.0 huggingface dataset:
English: Vectormune ND is a veterinary vaccine used to protect chickens against Newcastle disease (ND) and Marek's disease (MD).
Maltese: Vectormune ND huwa mediċina veterinarja li tintuża għall-protezzjoni tat-tiġieġ kontra l-marda ta' Newcastle (ND) u l-marda ta' Marek (MD).
English: This is a summary of the European public assessment report (EPAR) for Vectormune ND.
Maltese: Dan huwa sommarju tar-rapport pubbliku Ewropew ta' valutazzjoni (EPAR) għal Vectormune ND.
English: Other information about Vectormune ND
Maltese: Informazzjoni oħra dwar Vectormune ND
English: Why is Vectormune ND approved?
Maltese: Għaliex ġie approvat Vectormune ND?
English: This summary was last updated in January 2018.
Maltese: Dan is-sommarju kien aġġornat l-aħħar f'Jannar 2018.
English: The vaccine protects against a type of Marek disease virus that can cause visible infection.
Maltese: Il-vaċċin jipproteġi kontra tip ta' virus tal-marda Marek li jista' jikkawża infezzjoni viżibbli.
English: ND is a viral infection of chickens which causes gasping and coughing, nervous signs (drooping wings, twisting of the head and neck, circling and paralysis), swelling of the tissues around the eyes and neck, greenish watery diarrhoea and reduced egg production.
Maltese: ND hija infezzjoni virali tat-tiġieġ li tikkawża qtugħ ta' nifs u sogħla, sinjali ta' nervożiżmu (ġwienaħ imedendlin, brim tar-ras u l-għonq, tidwir u paraliżi), nefħa tal-tessut madwar l-għajnejn u l-għonq, dijarrea maħlula ħadranija u tnaqqis fil-produzzjoni tal-bajd.
English: The active substance in Vectormune ND is a turkey herpesvirus (rHVT/ND) that does not cause disease in chickens and has been modified so that it also produces one of the proteins of a strain of Newcastle disease virus (D-26 lentogenic strain).
Maltese: Is-sustanza attiva f'Vectormune ND hija virus tal-erpete tad-dundjani (rHVT/ND) li ma jikkawżax mard fit-tiġieġ u li ġiet modifikata biex tipproduċi wkoll waħda mill-proteini ta' razza tal-virus tal-marda ta' Newcastle (razza lentoġenika D-26).
English: Newcastle disease and Marek's disease vaccine (live recombinant)
Maltese: Vaċċin tal-marda ta' Newcastle u tal-marda ta' Marek (rikombinanti ħaj)
English: Nine-dayold broilers from the chicks vaccinated at one-day-old were challenged with MD virus and Vectormune ND provided protection to 90% of the chickens compared with 9-12% in the unvaccinated group.
Maltese: Tiġieġ tas-simna ta' disat ijiem minn flieles imlaqqmin meta kellhom jum kienu sfidati bil-virus MD u Vectormune ND ipprovda protezzjoni għal 90% tat-tiġieġ meta mqabbel ma' 9-12% fil-grupp mhux imlaqqam.
English: For MD protection starts at one week of age and lasts for the risk period of infection with MD.
Maltese: Għal MD, il-protezzjoni tibda mill-età ta' ġimgħa u ddum għallperjodu ta' riskju ta' infezzjoni b'MD.
English: MD is a herpesvirus infection of chickens which can cause paralysis of the wings and legs and causes tumours in various organs.
Maltese: MD hija infezzjoni tal-virus tal-erpete tat-tiġieġ li tista' tikkawża paraliżi tal-ġwienaħ u tas-saqajn u tikkawża tumuri f'diversi organi.
English: What are the risks associated with Vectormune ND?
Maltese: X'inhuma r-riskji assoċjati ma' Vectormune ND?
English: Safety studies have shown that the strain is safe for turkeys.
Maltese: Studji tas-sigurtà wrew li r-razza mhijiex ta' periklu għad-dundjani.
English: The European Commission granted a marketing authorisation valid throughout the EU for Vectormune ND on 8 September 2015.
Maltese: Il-Kummissjoni Ewropea tat awtorizzazzjoni għat-tqegħid fis-suq għal Vectormune ND valida fl-UE kollha fit-8 ta' Settembru 2015.
English: Birds infected with MD virus can be carriers and shedders of the virus for life.
Maltese: Għasafar infettati bil-virus MD jistgħu jkunu trasportaturi u xerrieda tal-virus tul ħajjithom kollha.
English: Twenty-two Vectormune ND vaccinated day-old layer chickens from this study were challenged at day 21 in the laboratory with ND strain and had no clinical signs for up to 2 weeks after challenge while all of 12 unvaccinated birds used for comparison died.
Maltese: Tnejn u għoxrin tiġieġa ta' jum u li huma intiżi biex ibidu l-bajd u li ġew imlaqqma b'Vectormune ND minn dan l-istudju kellhom sfida fil-21 jum fil-laboratorju b'razza ND u ma kellhom ebda sinjal kliniku sa ġimagħtejn wara l-isfida, filwaqt li t-12-il tajra mhux imlaqqma li ntużaw bħala paragun, mietu kollha.
English: Four-week-old chickens from the group of one-day-old vaccinated chicks were challenged with ND virus and Vectormune ND provided protection in 95% of the chickens compared with 0-10% in the non-vaccinated group.
Maltese: Tiġieġ ta' erba' ġimgħat mill-grupp ta' flieles imlaqqmin ta' jum kienu sfidati bil-virus ND u Vectormune ND ipprovda protezzjoni f'95% tat-tiġieġ meta mqabbel ma' 0-10% fil-grupp mhux imlaqqam.
English: For ND protection starts at 3 weeks of age and lasts until 9 weeks of age for broilers (chickens bred for meat) and 18 weeks of age for layers (chickens bred for egg production).
Maltese: Għal ND, il-protezzjoni tibda mill-età ta' 3 ġimgħat u ddum sa 9 ġimgħat għat-tiġieġ tas-simna (tiġieġ imrobbi għal-laħam) u 18-il ġimgħa għat-tiġieġ li jbidu (tiġieġ imrobbija għall-produzzjoni tal-bajd).
English: Vectormune ND is available as a suspension and solvent to be made into a suspension for injection and can only be obtained with a prescription.
Maltese: Vectormune ND huwa disponibbli bħala sospensjoni u solvent biex jiġu magħmulin f'sospensjoni għal injezzjoni u jista' jinkiseb biss b'riċetta ta' tabib.
English: In the future if the animals are exposed to a similar virus and/or to a virus expressing a similar fusion protein, the immune system will be able to respond more quickly.
Maltese: Jekk fil-futur lannimali jkunu esposti għal virus simili u/jew għal virus li jesprimi proteina ta' fużjoni simili, is-sistema immunitarja tkun kapaċi tirreaġixxi aktar malajr.
English: Nine-day-old broilers from vaccinated eggs were challenged with MD virus and 85% of the chickens were protected compared with 9% in the unvaccinated group.
Maltese: Tiġieġ tas-simna ta' disat ijiem minn bajd mhux imlaqqam kienu sfidati bil-virus MD u 85% tat-tiġieġ kienu protetti meta mqabbel ma' 9% fil-grupp mhux imlaqqam.
English: Nineday-old broilers from the group of chicks vaccinated at one-day-old were challenged with MD virus and 82% of the chickens were protected compared with 12% in the unvaccinated group.
Maltese: Tiġieġ tas-simna ta' disat ijiem mill-grupp ta' flieles imlaqqmin meta kellhom jum kienu sfidati bil-virus MD u 82% tat-tiġieġ kienu protetti meta mqabbel ma' 12% fil-grupp mhux imlaqqam.
English: This will help protect the chickens against ND and MD.
Maltese: Dan ser jgħin jipproteġi lit-tiġieġ kontra ND u MD.
English: In a third field study around 10,000 one-day-old layer chickens were vaccinated with Vectormune ND and a similar number with a vaccine against ND alone.
Maltese: Fit-tielet studju fuq il-post madwar 10,000 tiġieġa ta' jum u li ser ikunu intiżi biex ibidu l-bajd tlaqqmu b'Vectormune ND u numru simili b'vaċċin kontra ND waħdu.
English: Five-week-old chickens from the vaccinated one-day-old chicks were challenged with ND virus and 81% of vaccinated chickens were protected compared with no protection in the unvaccinated group.
Maltese: Tiġieġ ta' ħames ġimgħat mill-flieles ta' jum imlaqqmin kienu sfidati bil-virus ND u 81% tat-tiġieġ imlaqqmin kienu protetti meta mqabbel mal-ebda protezzjoni fil-grupp mhux imlaqqam.
English: Four-week-old chickens from vaccinated eggs were challenged with ND virus and 86% of the chickens were protected compared with 0-10% in the unvaccinated group.
Maltese: It-tiġieġ ta' erba' ġimgħat minn bajd imlaqqam kienu sfidati bil-virus ND u 86% tat-tiġieġ kienu protetti meta mqabbel ma' 0-10% fil-grupp mhux imlaqqam.
English: Nine-day-old chickens from vaccinated eggs were challenged with MD virus and 88% of the chickens were protected compared with 9-12% in the unvaccinated group.
Maltese: Tiġieġ ta' disat ijiem minn bajd mhux imlaqqam kienu sfidati bil-virus MD u 88% tat-tiġieġ kienu protetti meta mqabbel ma' 912% fil-grupp mhux imlaqqam.
English: For further information see the summary of product characteristics.
Maltese: Għal aktar informazzjoni, ara s-sommarju tal-karatteristiċi tal-prodott.
English: In the first field study a group of 18-day-old eggs containing embryos and a group of one-day-old chicks were vaccinated with Vectormune ND.
Maltese: Fit-tieni studju fuq il-post, grupp ta' bajd bl-embrijuni ta' 18-il jum u grupp ta' flieles ta' jum tlaqqmu b'Vectormune ND.
English: Five-week-old chickens from the vaccinated eggs were challenged with ND virus and 91% of vaccinated chickens were protected compared with no protection in the unvaccinated group.
Maltese: Tiġieġ ta' ħames ġimgħat mill-bajd imlaqqam kienu sfidati bil-virus ND u 91% tattiġieġ imlaqqmin kienu protetti meta mqabbel mal-ebda protezzjoni fil-grupp mhux imlaqqam.
English: Since no natural outbreaks of ND and MD occurred the chickens were challenged (exposed to infection) in the laboratory.
Maltese: Ladarba ma seħħ l-ebda tixrid naturali ta' ND u MD, it-tiġieġ ġew sfidati (esposti għallinfezzjoni) fil-laboratorju.
English: Thiamazole (synonym: methimazole)
Maltese: Thiamazole (sinonimu: methimazole)
English: Adopted at the 26-29 November 2018 PRAC
Maltese: Adottata fil-PRAC ta' bejn is-26-29 ta' Novembru 2018
English: Perindopril - Raynaud's phenomenon (EPITT no 19248)
Maltese: Perindopril - Fenomenu ta' Raynaud (EPITT Nru 19248)
English: Contraindications
Maltese: .3. Kontraindikazzjonijiet
English: Tabulated list of adverse reactions Vascular disorders
Maltese: Tabella b'lista ta' reazzjonijiet avversi Disturbi vaskulari
English: Other medicines and Bydureon
Maltese: Mediċini oħra u Bydureon
English: Carbimazole; thiamazole - Pancreatitis (EPITT no 19274)
Maltese: 3. Carbimazole; thiamazole - Pankreatite (EPITT Nru 19274)
English: Reported malformations include aplasia cutis congenita, craniofacial malformations (choanal atresia; facial dysmorphism), exomphalos, oesophageal atresia, omphalo-mesenteric duct anomaly, and ventricular septal defect.
Maltese: Malformazzjonijiet irrappurtati jinkludu aplasia cutis congenita, malformazzjonijiet tal-kranju u tal-wiċċ (choanal atresia; dismorfiżmu tal-wiċċ), exomphalos, atresia esofagali, anomalija tal-kanal taomphalomesenteric, u difett septali ventrikulari.
English: Frequency ‘not known': Raynaud's phenomenon
Maltese: Frekwenza "mhux magħrufa": Fenomenu ta' Raynaud
English: Canagliflozin; dapagliflozin; empagliflozin; ertugliflozinFournier's gangrene (EPITT no 19308)
Maltese: 1. Canagliflozin; dapagliflozin; empagliflozin; ertugliflozinkankrena ta' Fournier (EPITT nru 19308)
English: Dulaglutide; exenatide; liraglutide - Diabetic ketoacidosis (EPITT no 19237)
Maltese: Dulaglutide; exenatide; liraglutide - Ketoaċidożi dijabetika (EPITT Nru 19237)
English: Other medicines and Trulicity
Maltese: Mediċini oħra u Trulicity
English: Certolizumab pegol; etanercept; golimumab; infliximabLichenoid skin reactions (EPITT no 19128)
Maltese: 4. Certolizumab pegol; etanercept; golimumab; infliximabReazzjonijiet tal-ġilda likenojdi (EPITT Nru 19128)
English: If Fournier's gangrene is suspected, X should be discontinued and prompt treatment (including antibiotics and surgical debridement) should be instituted.
Maltese: Jekk ikun hemm suspett ta' kankrena ta' Fournier, X għandu jitwaqqaf u jinbeda trattament fil-pront (li jinkludi antibijotiċi u t-tneħħija kirurġika tal-parti affettwata).
English: Posology and method of administration Add-on therapy
Maltese: Pożoloġija u metodu ta' kif għandu jingħata Terapija add-on
English: Not known (frequency cannot be estimated from the available data) …inflammation of the pancreas (acute pancreatitis).
Maltese: Mhux magħruf (il-frekwenza ma tistax tiġi stmata mid-data disponibbli) …infjammazzjoni tal-frixa (pankreatite akuta).
English: Necrotising fasciitis of the perineum (Fournier´s Gangrene)1 Frequency: not known
Maltese: Infezzjonijiet u infestazzjonijiet Fasciitis nekrotika tal-perineum (Kankrena ta' Fournier)1 Frekwenza: mhux magħrufa 1 ara sezzjoni 4.4
English: Patients with a history of acute pancreatitis after administration of carbimazole or its active metabolite thiamazole.
Maltese: Pazjenti b'passat ta' pankreatite akuta wara l-għoti ta' carbimazole jew tal-metabolit attiv tiegħu thiamazole.
English: Undesirable effects Tabulated list of adverse reactions Skin and subcutaneous tissue disorders Frequency ‘rare': Lichenoid reactions
Maltese: Disturbi fil-ġilda u fit-tessuti ta' taħt il-ġilda Frekwenza “rari”:
English: Thiamazole is able to cross the human placenta.
Maltese: Thiamazole jista' jgħaddi mill-plaċenta tal-bniedem.
English: Lichenoid reactions (itchy reddish-purple skin rash and/or threadlike white-grey lines on mucous membranes) with frequency ‘rare'
Maltese: Reazzjonijiet likenojdi (raxx tal-ġilda ħamrani fil-vjola bil-ħakk u/jew ħjut bojod fil-griż fuq il-membrani mukużi) bi frekwenza "rari"
English: Warnings and precautions …Tell your doctor straight away if you develop fever or abdominal pain, which may be signs of inflammation of the pancreas (acute pancreatitis).
Maltese: Twissijiet u prekawzjonijiet …Kellem lit-tabib tiegħek minnufih jekk jitlagħlek id-deni jew jaqbdek uġigħ addominali, li jistgħu jkunu sinjali ta' infjammazzjoni tal-frixa (pankreatite akuta).
English: Women of childbearing potential have to use effective contraceptive measures during treatment.
Maltese: Jekk tista' tinqabad tqila, uża kontraċettiv affidabbli minn meta tibda t-trattament u waqt it-trattament.
English: Carbimazole; thiamazole - New information on the known risk of birth defects and neonatal disorders in case of exposure during pregnancy (EPITT no 19238)
Maltese: 2. Carbimazole; thiamazole - Informazzjoni ġdida dwar irriskju magħruf ta' difetti tat-twelid u disturbi fit-trabi tattwelid f'każ ta' esponiment waqt it-tqala (EPITT Nru 19238)
English: Thiamazole must only be administered during pregnancy after a strict individual benefit/risk assessment and only at the lowest effective dose without additional administration of thyroid hormones.
Maltese: Thiamazole għandu jingħata biss waqt it-tqala wara valutazzjoni individwali tar-riskji u tal-benefiċċji u biss fl-iżgħar doża effettiva mingħajr għoti addizzjonali ta' ormoni tat-tirojde.
English: Carbimazole must only be administered during pregnancy after a strict individual benefit/risk assessment and only at the lowest effective dose without additional administration of thyroid hormones.
Maltese: Carbimazole għandu jingħata biss waqt it-tqala wara valutazzjoni individwali tar-riskji u tal-benefiċċji u biss fl-iżgħar doża effettiva mingħajr għoti addizzjonali ta' ormoni tat-tirojde.
English: Frequency ‘not known': Acute pancreatitis
Maltese: Pankreatite akuta
English: In case of acute pancreatitis, thiamazole should be discontinued immediately.
Maltese: F'każ ta' pankreatite akuta, thiamazole għandu jitwaqqaf minnufih.
English: Carbimazole is able to cross the human placenta.
Maltese: Carbimazole jista' jgħaddi mill-plaċenta tal-bniedem.
English: If you could get pregnant, use reliable contraception from the time you start treatment and during treatment.
Maltese: Jekk tista' tinqabad tqila, uża kontraċettiv affidabbli minn meta tibda t-trattament u waqt ittrattament.
English: There have been post-marketing reports of acute pancreatitis in patients receiving carbimazole or its active metabolite thiamazole.
Maltese: Kien hemm rapporti ta' wara t-tqegħid fis-suq ta' pankreatite akuta f'pazjenti li ngħataw carbimazole jew il-metabolit attiv tiegħu thiamazole.
English: When initiating Saxenda, consider reducing the dose of concomitantly administered insulin or insulin secretagogues (such as sulfonylureas) to reduce the risk of hypoglycaemia.
Maltese: Meta tibda Saxenda, ikkunsidra li tnaqqas id-doża ta' insulina jew ta' sustanzi li jistimulaw issekrezzjoni tal-insulina (bħal sulfonylureas) mogħtija fl-istess ħin biex tnaqqas ir-riskju ta' ipogliċemija.
English: These symptoms could be a sign of a rare but serious or even life-threatening infection, called necrotizing fasciitis of the perineum or Fournier's gangrene which destroys the tissue under the skin.
Maltese: Dawn is-sintomi jistgħu jkunu sinjal ta' infezzjoni rari iżda serja jew saħansitra ta' periklu għall-ħajja, msejħa fasciitis nekrotika tal-perineum jew kankrena ta' Fournier li teqred it-tessut ta' taħt il-ġilda.
English: Talk to your doctor immediately if you develop a combination of symptoms of pain, tenderness, redness, or swelling of the genitals or the area between the genitals and the anus with fever or feeling generally unwell.
Maltese: Kellem lit-tabib tiegħek immedjatament jekk tiżviluppa taħlita ta' sintomi ta' wġigħ, sensittività, ħmura, jew nefħa tal-ġenitali jew taż-żona bejn il-ġenitali u l-anus flimkien ma' deni jew sensazzjoni li ma tiflaħx.
English: Prolonged-release exenatide is not a substitute for insulin.
Maltese: Twissijiet speċjali u prekawzjonijiet għall-użu Exenatide mhuwiex sostitut għall-insulina.
English: Necrotising fasciitis of the perineum or Fournier´s gangrene, a serious soft tissue infection of the genitals or the area between the genitals and the anus.
Maltese: Fasciitis nekrotika tal-perineum jew kankrena ta' Fournier, infezzjoni serja tat-tessut artab tal-ġenitali jew taż-żona bejn il-ġenitali u l-anus.
English: Fournier´s gangrene has to be treated immediately.
Maltese: Il-kankrena ta' Fournier trid tiġi ttrattata immedjatament.
English: If carbimazole is used during pregnancy, the lowest effective dose without additional administration of thyroid hormones should be administered.
Maltese: Jekk carbimazole jintuża waqt it-tqala, għandha tingħata l-iżgħar doża effettiva mingħajr lgħoti addizzjonali ta' ormoni tit-tirojde.
English: There have been post-marketing reports of acute pancreatitis in patients receiving thiamazole or its prodrug carbimazole.
Maltese: Kien hemm rapporti ta' wara t-tqegħid fis-suq ta' pankreatite akuta f'pazjenti li ngħataw thiamazole jew il-promediċina tiegħu carbimazole.
English: Blood glucose selfmonitoring is necessary to adjust the dose of sulphonylurea or insulin, particularly when Byetta therapy is started and insulin is reduced.
Maltese: Trulicity mhuwiex insulina u għaldaqstant m'għandux jintuża bħala sostitut għall-insulina.
English: What you need to know before you take <medicinal product> Do not take <medicinal product> …if you had inflammation of the pancreas (acute pancreatitis) after administration of thiamazole or carbimazole in the past…
Maltese: X'għandek tkun taf qabel ma tieħu <il-prodott mediċinali> Tiħux <il-prodott mediċinali> …jekk kellek infjammazzjoni tal-frixa (pankreatite akuta) wara li ngħatajt thiamazole jew carbimazole fil-passat…
English: Dulaglutide is not a substitute for insulin.
Maltese: Twissijiet speċjali u prekawzjonijiet għall-użu Dulaglutide mhuwiex sostitut għall-insulina.
English: Strength Pharmaceutical Form Route of Administration Packaging
Maltese: Qawwa Għamla Farmaċewtika Mnejn Jingħata
English: Strength Pharmaceutical Form
Maltese: 15-il pillola
English: EMA Number
Maltese: Numru tal- proċedura ta' l-EMA
English: Celsentri is available as tablets (25, 75, 150 and 300 mg) and as a liquid (20 mg/ml) to be taken by mouth.
Maltese: Celsentri jiġi bħala pilloli (25, 75, 150, u 300 mg) u bħala likwidu (20 mg/ml) li għandu jittieħed millħalq.
English: The full EPAR for Celsentri can be found on the Agency's website ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Maltese: L-EPAR sħiħ għal Celsentri jista' jinstab fis-sit elettroniku tal-Aġenzija ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: This summary was last updated in 05-2017.
Maltese: Dan is-sommarju ġie aġġornat l-aħħar f'05-2017.
English: Celsentri contains the active substance maraviroc.
Maltese: Celsentri fih is-sustanza attiva maraviroc.
English: The active substance in Celsentri, maraviroc, is a ‘CCR5 antagonist'.
Maltese: Is-sustanza attiva f'Celsentri, maraviroc, hija ‘antagonista tas-CCR5'.
English: Other information about Celsentri
Maltese: Informazzjoni oħra dwar Celsentri
English: Celsentri has been shown to be effective at reducing the levels of HIV in the blood in two main studies involving a total of 1,076 mostly adult patients with CCR5-tropic HIV infection.
Maltese: Celsentri wera li kien effettiv fit-tnaqqis tal-livelli tal-HIV fid-demm f'żewġ studji ewlenin li fihom ħadu sehem total ta' 1,076 pazjent, l-aktar adulti, b'infezzjoni HIV CCR5-tropic.
English: This is a summary of the European public assessment report (EPAR) for Celsentri.
Maltese: Dan huwa sommarju tar-rapport pubbliku Ewropew ta' valutazzjoni (EPAR) għal Celsentri.
English: Why is Celsentri approved?
Maltese: Għaliex ġie approvat Celsentri?
English: In adults, the recommended dose is 150, 300 or 600 mg twice a day, depending on the other medicines that the patient is taking.
Maltese: Fl-adulti, id-doża rakkomandata hija 150, 300 jew 600 mg darbtejn kuljum, skont il-mediċini loħra li l-pazjent ikun qed jieħu.
English: Celsentri is an HIV medicine used to treat patients from 2 years of age and weighing at least 10 kg who are infected with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Maltese: Celsentri huwa mediċina kontra l-HIV li tintuża għall-kura ta' pazjenti minn sentejn ‘il fuq li jiżnu minn tal-inqas 10 kg u li huma infettati bil-virus tal-immunodefiċjenza umana tat-tip-1 (HIV-1), virus li jikkawża s-sindrome ta' immunodefiċjenza akkwiżita (AIDS).
English: The European Commission granted a marketing authorisation valid throughout the European Union for Celsentri on 18 September 2007.
Maltese: Il-Kummissjoni Ewropea tat awtorizzazzjoni għat-tqegħid fis-suq għal Celsentri valida fl-Unjoni Ewropea kollha fit-18 ta' Settembru 2007.
English: The proportion of patients who had undetectable levels of HIV in their blood after 24 weeks was about 45% with Celsentri compared to 23% with placebo.
Maltese: Il-proporzjon ta' pazjenti li kellhom livelli li ma jingħarfux ta' HIV fid-demm tagħhom wara 24 ġimgħa kien madwar 45% b'Celsentri meta mqabbel ma' 23% bilplaċebo.
English: What are the risks associated with Celsentri?
Maltese: X'inhuma r-riskji assoċjati ma' Celsentri?
English: Celsentri maraviroc
Maltese: Sommarju tal-EPAR għall-pubbliku maraviroc
English: Celsentri used in combination with other HIV medicines has been shown to be effective at reducing the levels of HIV in the blood in adults, and similar effects are expected in children.
Maltese: Celsentri użat flimkien ma' mediċini oħra kontra l-HIV wera li kien effettiv fit-tnaqqis tal-livelli ta' HIV fid-demm fl-adulti, u effetti simili huma mistennija fit-tfal.
English: It blocks the CCR5 protein on the surface of the cells in the body that HIV infects.
Maltese: Din timblokka l-proteina CCR5 fuq il-wiċċ taċ-ċelloli fil-ġisem li jiġu infettati mill-HIV.
English: The most common side effects with Celsentri (which may affect up to 1 in 10 people) are nausea (feeling sick), diarrhoea, fatigue (tiredness) and headache.
Maltese: L-effetti sekondarji l-aktar komuni b'Celsentri (li jistgħu jaffettwaw sa persuna 1 minn kull 10) huma dardir (tħossok ma tiflaħx), dijarea, eżawriment (għeja) u wġigħ ta' ras.
English: Looking at the results of the two studies taken together, the levels of HIV in the blood had fallen by an average of 99% after 24 weeks in the patients adding Celsentri to optimised background therapy, compared with 90% in those adding placebo.
Maltese: Meta wieħed iħares lejn ir-riżultati taż-żewġ studji meħudin flimkien, il-livelli tal-HIV fid-demm naqsu b'medja ta' 99% wara 24 ġimgħa fil-pazjenti li żiedu Celsentri ma' terapija ta' bażi ottimizzata, meta mqabbla ma' 90% f'dawk li żiedu plaċebo.
English: CCR5-tropic HIV uses this protein to enter the cells.
Maltese: L-HIV CCR5-tropic juża din il-proteina biex jidħol fiċ-ċelloli.
English: Additional data indicate that Celsentri given at a suitable dose to children is handled by their body in the same way as in adults.
Maltese: Abbażi ta' din id-data, l-effikaċja hija mistennija li tkun simili fit-tfal u fl-adulti.