FrancophonIA/ELRC3.0 huggingface dataset:
English: Small treatment group differences in decline of FEV1 were observed in the EXUBERA group relative to comparator therapy.
Slovenian: V skupini z zdravilom EXUBERA so v primerjavi s skupino, zdravljeno s primerjalnim zdravilom, opazili majhne razlike v zmanjšanju FEV1 .
English: For instructions on how to look after your insulin inhaler see “Instructions for Use” at the end of the package leaflet.
Slovenian: Navodila o tem, kako skrbeti za insulinski inhalator, boste našli v “Navodilu za uporabo insulinskega inhalatorja”, ki se nahaja na koncu tega navodila.
English: If the 3 mg blister is temporarily unavailable, two 1 mg blisters should be substituted and blood glucose monitored closely.
Slovenian: Če bolnik trenutno nima na voljo 3-mg pretisnega omota, naj uporabi dva 1-mg pretisna omota in naj natančno nadzira glukozo v krvi.
English: In clinical trials involving patients with type 2 diabetes not sufficiently controlled with oral agents alone, patients using a regimen of EXUBERA alone or in combination with oral agents, had greater improvements in HbA1c compared with patients treated with oral agents alone.
Slovenian: V kliničnih preskušanjih na bolnikih z diabetesom tipa 2, pri katerih glikemična kontrola samo s peroralnimi antidiabetiki ni zadostna, se je HbA1c bolj izboljšal pri bolnikih, zdravljenih s shemami z zdravilom EXUBERA samim ali v kombinaciji s peroralnimi antidiabetiki, kot pri bolnikih, zdravljenih samo s peroralnimi antidiabetiki.
English: Patients in a clinical trial for type 2 diabetes, who used a regimen of EXUBERA in combination with long- or intermediate-acting insulin, had similar changes in HbA1c compared with patients treated
Slovenian: Bolniki z diabetesom tipa 2, ki so v kliničnem preskušanju uporabljali shemo z zdravilom EXUBERA v kombinaciji z dolgo- ali srednjedolgo-delujočim insulinom, so imeli podobne spremembe HbA1c kot bolniki, zdravljeni samo s subkutanim insulinom.
English: Observed Change from Baseline in FEV1 (L) in patients with type 1 diabetes mellitus.
Slovenian: Opažena sprememba FEV1 (L) od izhodišča pri bolnikih z diabetesom mellitusom tipa 1.
English: Also, read the Patient Information Leaflet for, EXUBERA 1 mg and 3 mg powder for inhalation predispensed.
Slovenian: Preberite tudi navodilo za uporabo za zdravilo EXUBERA 1 mg in 3 mg prašek za inhaliranje, odmerjen.
English: If you need dose titrations of less than 1 mg it is recommended you do not use EXUBERA (see section 3 “How to take EXUBERA” for further advice and section 6 “Further information”).
Slovenian: Če imate nizko telesno maso ali potrebujete prilagoditve odmerkov, manjše od 1 mg, se posvetujte z zdravnikom, ali lahko uporabljate zdravilo EXUBERA (glejte poglavje 3 “Kako uporabljati zdravilo EXUBERA” in poglavje 6 “Dodatne informacije”).
English: In type 1 subjects, resolution of small treatment group differences (0.010L favouring comparator) occurred within 2 weeks of EXUBERA cessation following 12 weeks of therapy.
Slovenian: Pri bolnikih z diabetesom tipa 1 so majhne razlike med skupinama, zdravljenima z različnima zdraviloma (0,010 L v korist primerjalnega zdravila), izginile v dveh tednih po ukinitvi zdravila EXUBERA po 12 tednih zdravljenja.
English: There has also been 1 post-marketing report of a primary lung malignancy in an Exubera-treated patient.
Slovenian: V pomarketinškim obdobju je bil opisan 1 primer primarnega malignoma pljuč pri bolniku, zdravljenem z zdravilom EXUBERA.
English: Squeeze the two chamber release buttons at the same time on the side of the base.
Slovenian: Hkrati stisnite oba gumba za sproščanje komore, ki sta ob straneh podnožja.
English: Both EXUBERA and comparator treated subjects experienced declines in lung function over time during these trials (Figures 2 and 3).
Slovenian: Tako pri bolnikih, zdravljenih z zdravilom EXUBERA, kot pri bolnikih, zdravljenih s primerjalnim zdravilom, se je med temi preskušanjih sčasoma zmanjšala pljučna funkcija (sliki 2 in 3).
English: EXUBERA should not be taken during pregnancy.
Slovenian: Zdravila EXUBERA med nosečnostjo ne smete jemati.
English: In this case you must change the Insulin Release Unit (IRU) prior to your
Slovenian: V tem primeru morate pred naslednjo inhalacijo nastavek za sproščanje insulina (Insulin release unit - IRU) zamenjati.
English: The intra-subject variability of glucose lowering activity of inhaled human insulin was generally comparable to that of subcutaneously administered fast-acting human insulin in subjects with type 1
Slovenian: Variabilnost aktivnosti zniževanja glukoze humanega insulina za inhaliranje je bila na splošno primerljiva s tisto pri subkutano apliciranem hitrodelujočem humanem insulinu pri bolnikih z
English: In patients with hepatic or renal impairment insulin requirements may be diminished.
Slovenian: Okvare jeter in ledvic Pri bolnikih z okvaro jeter ali ledvic utegnejo biti potrebe po insulinu zmanjšane.
English: For instructions on how to attach the chamber to the base refer to the section “Put your insulin
Slovenian: Za navodila, kako sestaviti komoro s podnožjem, glejte poglavje “Sestavite insulinski inhalator”.
English: There is no experience on the use of EXUBERA in pregnant women.
Slovenian: Z uporabo zdravila EXUBERA pri nosečnicah ni izkušenj.
English: Observed Change from Baseline in FEV1 (L) in patients with type 2 diabetes mellitus.
Slovenian: Opažena sprememba FEV1 (L) od izhodišča pri bolnikih z diabetesom mellitusom tipa 2.
English: The bottom of the chamber MUST be above the grey button.
Slovenian: Spodnji rob komore MORA biti
English: In type 2 subjects, resolution of small treatment group differences (0.039L favouring comparator) occurred within 6 weeks of EXUBERA cessation following 2 years of therapy (Figure 3).
Slovenian: Pri bolnikih z diabetesom tipa 2 so majhne razlike med skupinama, zdravljenima z različnima zdraviloma (0,039 L v korist primerjalnega zdravila), izginile v šestih tednih po ukinitvi zdravila EXUBERA po 2 letih zdravljenja (slika 3).
English: When an EXUBERA treated patient becomes pregnant appropriate subcutaneous insulin should be substituted for inhaled insulin.
Slovenian: Če bolnica, ki uporablja EXUBERO, zanosi, je treba EXUBERO nadomestiti z ustreznim subkutanim insulinom.
English: If the insulin inhaler is inadvertently exposed to extremely moist conditions during use this usually leads to a subsequent decreased the insulin dose delivered from the inhaler.
Slovenian: Če je insulinski inhalator med uporabo po nepazljivosti izpostavljen izredno vlažnemu okolju, to najverjetneje povzroči, da sprosti manjši odmerek insulina.
English: The IRU must be changed after accidental exposure to extremely moist conditions, e.g. steamy bathroom.
Slovenian: Prav tako ga morate zamenjati tudi po naključni izpostavitvi inhalatorja izredno vlažnemu okolju, npr. v
English: There is no clinical experience with EXUBERA use in pregnancy.
Slovenian: Z uporabo zdravila EXUBERA med nosečnostjo ni kliničnih izkušenj.
English: Inform your doctor or nurse if you are planning to become pregnant or if you are already pregnant.
Slovenian: Če nameravate zanositi ali ste že noseči, o tem obvestite zdravnika ali medicinsko sestro.
English: A 1 mg unit dose blister is approximately equal to 3 IU of fast-acting subcutaneous insulin and a 3 mg unit dose blister is approximately equal to 8 IU of fast-acting subcutaneous insulin.
Slovenian: 1-mg enoodmerni pretisni omot ustreza približno 3 i.e. hitrodelujočega subkutanega insulina, 3-mg enoodmerni pretisni omot pa 8 i.e. hitrodelujočega subkutanega insulina.
English: A decline from baseline in FEV1 of > 15% occurred in 1.3% of EXUBERA-treated and 1.0% of comparator-treated type 1 subjects and in 5.0% of EXUBERA-treated and 3.4% of comparator-treated
Slovenian: Pri bolnikih z diabetesom tipa 1 se je zmanjšanje FEV1 za > 15 % od izhodišča pojavilo pri 1,3 % bolnikov, zdravljenih z zdravilom EXUBERA, in pri 1,0 % bolnikov, zdravljenih s primerjalnim zdravilom; pri bolnikih z diabetesom tipa 2 se je takšno zmanjšanje FEV1 pojavilo pri 5,0 % bolnikov, zdravljenih z zdravilom EXUBERA, in pri 3,4 % bolnikov, zdravljenih s primerjalnim zdravilom.
English: Each unit dose blister contains 1 mg or 3 mg of the active substance insulin human.
Slovenian: En enoodmerni pretisni omot vsebuje 1 mg ali 3 mg zdravilne učinkovine, humanega insulina.
English: oC. Store in the original package in order to protect from moisture.
Slovenian: Shranjujte pri temperaturi do 30o C. Shranjujte v originalni ovojnini za zagotovitev zaščite pred vlago.
English: Your blood sugar levels may fall too much, if for example: - you take too much insulin, - you miss meals or delay them, - you do not eat enough, or eat food containing less carbohydrate than normal (sugar and substances similar to sugar are called carbohydrates; however, artificial sweeteners are NOT carbohydrates), - you lose or are unable to consume carbohydrates due to vomiting or diarrhoea, - you drink alcohol, particularly if you are not eating much, - you take more physical exercise than usual or a different type of physical activity, - you are recovering from an injury or operation or other stress, - you are recovering from a feverish illness or from another illness, - you are taking or have stopped taking certain other medicines (see section 2, “Taking other
Slovenian: - izgubljate ali ne morete uživati ogljikovih hidratov zaradi bruhanja ali driske, - pijete alkohol, posebno še, če ne jeste veliko, - ste telesno bolj aktivni kot običajno ali je vaša telesna aktivnost drugačne vrste, - okrevate po poškodbi, operaciji ali kakem drugem stresu, - okrevate po vročinski bolezni ali kakšni drugi bolezni, - jemljete ali ste prenehali jemati nekatera druga zdravila (glejte poglavje 2 “Jemanje drugih zdravil”).
English: The exposure of human insulin following administration of three 1 mg blisters is significantly greater than that following a single 3 mg blister.
Slovenian: Izpostavljenost humanemu insulinu je po uporabi treh 1-mg pretisnih omotov bistveno večja kot po uporabi enega samega 3-mg pretisnega omota.
English: Randomised, open label parallel group studies were conducted to examine FEV1 changes following initiation of EXUBERA therapy in type 1 and 2 subjects.
Slovenian: Za raziskovanje sprememb FEV1 po uvedbi zdravljenja z zdravilom EXUBERA pri bolnikih z diabetesom tipa 1 in tipa 2 so opravili randomizirane odprte študije s paralelnimi skupinami.
English: Renal impairment
Slovenian: Okvare ledvic
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton/Unit dose blisters (60, 90, 180, 270)
Slovenian: PODATKI NA ZUNANJI OVOJNINI Škatla / enoodmerni pretisni omoti ( 60, 90, 180, 270)
English: In Phase 2/3 trials, 9 out of 2498 subjects treated with EXUBERA were discontinued from trials due to a decline in pulmonary function whose end of study FEV1 showed a decline of ≥ 15% from baseline.
Slovenian: V študijah 2. in 3. faze so zaradi poslabšanja pljučne funkcije (zmanjšanje FEV1 za 15 % ali več) prekinili terapijo pri devetih izmed 2498 oseb, ki so prejemali EXUBERO.
English: A decline from baseline in FEV1 of > 15% occurred in 1.3% of EXUBERA-treated type 1 subjects and in 5.0% of EXUBERA-treated type 2 subjects.
Slovenian: Zmanjšanje FEV1 za > 15 % od izhodišča se je pojavilo pri bolnikih z diabetesom tipa 1 pri 1,3 % bolnikov, zdravljenih z zdravilom EXUBERA, pri bolnikih z diabetesom tipa 2 pa pri 5,0 % bolnikov.
English: Fasting plasma glucose was similar to or lower in patients using a regimen including EXUBERA compared to patients treated with oral agents alone.
Slovenian: Plazemska glukoza na tešče je bila podobna ali nižja pri bolnikih, ki so uporabljali shemo, ki je vključevala zdravilo EXUBERA, kot pri bolnikih, zdravljenih samo s peroralnimi antidiabetiki.
English: Educational material shall consist of information aiming to minimise adverse events and support effective use through adequate education about:
Slovenian: Izobraževalna gradiva bodo obsegala informacije, namenjene minimizaciji neželenih dogodkov in bodo pripomogla k učinkoviti uporabi z ustreznim informiranjem o: a) potrebi po doslednem in standardnem načinu inhaliranja, ki naj zagotovi optimalen in b) posebnih previdnostnih ukrepih z inhalatorjem insulina,
English: (Seen in more than 1 in 10 patients)
Slovenian: Neželeni učinki, o katerih poročajo zelo pogosto (Pojavijo se pri več kot 1 od 10 bolnikov)
English: Hold the insulin inhaler in your hand.
Slovenian: Pripravite insulinski inhalator Držite insulinski inhalator v roki.
English: You should also tell your doctor if you develop any other increasing breathing difficulties while
Slovenian: Zdravniku morate povedati, če se vam med uporabo zdravila EXUBERA pojavijo kakšne druge
English: Each unit dose blister contains 1 mg insulin human.
Slovenian: En enoodmerni pretisni omot vsebuje 1 mg humanega insulina.
English: Three 1 mg blisters should not be substituted for one 3 mg blister (see section 2, “Take special care with EXUBERA” and section 3, “How to take EXUBERA”).
Slovenian: Enega 3-mg pretisnega omota ne smete nadomestiti s tremi 1-mg (glejte poglavje 2 “Bodite posebno pozorni pri uporabi zdravila EXUBERA” in poglavje 3 “Kako uporabljati
English: Changes to your sight may occur upon starting insulin therapy.
Slovenian: Po začetku zdravljenja z insulinom se lahko pojavijo spremembe vida.
English: Consecutive inhalation of three 1 mg unit dose blisters causes a significantly higher insulin exposure than inhalation of one 3 mg unit dose blister.
Slovenian: Zaporedno inhaliranje treh 1-mg pretisnih omotov za enkratni odmerek povzroči bistveno večjo izpostavljenost insulinu kot inhaliranje enega 3-mg pretisnega omota za enkratni odmerek.
English: If you accidentally expose your inhaler to moist conditions during use, this will usually decrease the dose of insulin you take.
Slovenian: Če inhalator med uporabo po nesreči izpostavite vlažnemu okolju, to ponavadi zmanjša vnešeni odmerek insulina.
English: Fasting plasma glucose levels were significantly lower in patients treated with EXUBERA regimens compared with those treated with subcutaneous insulin.
Slovenian: Koncentracije plazemske glukoze na tešče so bile pomembno nižje pri bolnikih, zdravljenih s shemami z zdravilom EXUBERA, kot pri bolnikih, zdravljenih s subkutanim insulinom.
English: Three 1 mg unit dose blisters should not be substituted for one 3mg blister (see section 2, “Take special care with EXUBERA”, section 3, “How to take EXUBERA” and section 6
Slovenian: Enega 3-mg pretisnega omota ne smete nadomestiti s tremi 1-mg pretisnimi omoti (glejte poglavje 2 “Bodite posebno pozorni pri uporabi zdravila EXUBERA”, poglavje 3 “Kako uporabljati zdravilo EXUBERA” in poglavje 6 “Dodatne informacije”).
English: Turn the used IRU about a one-quarter turn counter clockwise towards the unlock symbol.
Slovenian: Zasukajte rabljeni nastavek za sproščanje insulina za približno četrt obrata v smeri, nasprotni od smeri urnega kazalca, proti
English: For the 3 mg product, the spine of the blister card has three raised ridges with the individual blisters embossed with three raised dots each.
Slovenian: Pri jakosti 3 mg ima hrbtišče ploščice s pretisnimi omoti tri podolgovate izbokline, vsak od posamičnih pretisnih omotov pa po tri izbočene točke.
English: There is little experience with EXUBERA in patients older than 75 years.
Slovenian: Pri bolnikih, starejših od 75 let, imamo z zdravilom EXUBERA malo izkušenj.
English: If you have low body weight check with your doctor if you can use EXUBERA.
Slovenian: Če imate nizko telesno maso ali potrebujete prilagoditve odmerkov, manjše od 1 mg, se posvetujte z zdravnikom, ali lahko uporabljate zdravilo EXUBERA.
English: 6.4 Special precautions for storage Store below 30
Slovenian: 6.4 Posebna navodila za shranjevanje
English: Table 1 above presents the approximate IU dose of fast-acting human insulin for initial, pre-meal EXUBERA doses in mg.
Slovenian: Preglednica 1 prikazuje približno enakovreden odmerek v i.e. hitrodelujočega humanega insulina za začetne odmerke EXUBERE pred
English: HOW TO TAKE EXUBERA
Slovenian: Kako se pripravite, da boste vzeli zdravilo EXUBERA
English: Do not blow into the
Slovenian: Ne pihajte v ustnik.
English: For the 1 mg product, the spine of the blister card has one raised ridge with the individual blisters embossed with one raised dot each.
Slovenian: Pri jakosti 1 mg ima hrbtišče ploščice s pretisnimi omoti eno podolgovato izboklino, vsak od posamičnih pretisnih omotov pa po eno izbočeno točko.
English: Caution: please remember that artificial sweeteners and foods with artificial sweeteners (e.g. diet drinks) are of no help in hypoglycaemia.
Slovenian: (Enkrat si stehtajte polno žlico ali sladkorne kocke ali glukozne tablete, da boste videli, koliko je to.) Opozorilo: ne pozabite, da umetna sladila in jedi z umetnimi sladili (npr. dietne pijače) pri hipoglikemiji čisto nič ne pomagajo.
English: Hold your insulin inhaler in your hand.
Slovenian: Insulinski inhalator razstavite Držite insulinski inhalator v roki.
English: Store your insulin inhaler in a dry place at room
Slovenian: Insulinski inhalator shranjujte na suhem pri sobni
English: Taking three separate 1 mg blisters delivers more insulin to your lungs than a single 3 mg blister does.
Slovenian: Uporaba treh ločenih 1-mg pretisnih omotov prinese v pljuča več insulina kot uporaba enega samega 3-mg pretisnega omota.
English: Put your insulin inhaler together Line the top of the base with the open end of the chamber.
Slovenian: Poravnajte vrh podnožja z odprtim koncem komore.
English: Alcohol may intensify and prolong
Slovenian: Alkohol lahko okrepi in podaljša hipoglikemični učinek insulina.
English: Always make sure you have the correct blisters available before using your insulin inhaler.
Slovenian: Pred uporabo insulinskega inhalatorja vedno preverite, ali imate pripravljene pravilne pretisne omote.
English: In subjects with type 1 diabetes mellitus, inhaled human insulin had a comparable intrasubject variability of AUC to subcutaneously administered fast-acting human insulin.
Slovenian: Pri preiskovancih z diabetesom mellitusom tipa 1 je bila intraindividualna variabilnost AUC humanega insulina za inhaliranje primerljiva kot pri subkutano apliciranem hitrodelujočem humanem insulinu.
English: You should avoid taking EXUBERA in moist conditions e.g. a bathroom following a steamy shower as this will usually give you a lower insulin dose than you need (see package leaflet
Slovenian: Zdravila EXUBERA ne smete uporabljati v vlažnem okolju, npr. v kopalnici po prhi, ki povzroči veliko pare, saj boste zaradi tega v telo najverjetneje vnesli manjši odmerek insulina, kot ga potrebujete (za nasvet glejte ločeno navodilo za uporabo pretisnih omotov).
English: Approximate guidelines for initial, pre-meal EXUBERA doses, based on patient body weight, are
Slovenian: Okvirne smernice za začetne odmerke zdravila EXUBERA, aplicirane pred obroki, na podlagi bolnikove telesne mase, kaže preglednica 1:
English: Small treatment group differences (favouring comparator) in change from baseline of 0.034L in type 1 and 0.039L in type 2 occurred after 2 years of therapy.
Slovenian: Po 2 letih zdravljenja so se pojavile majhne razlike med skupinami, zdravljenimi z različnimi zdravili (v korist primerjalnega zdravila), sprememba od izhodišča je bila 0,034 L pri tipu 1 in 0,039 L pri tipu 2.
English: Push the base back into the chamber to store.
Slovenian: Potisnite podnožje nazaj v komoro in inhalator shranite.
English: EXUBERA 1 mg inhalation powder pre-dispensed EXUBERA 3 mg inhalation powder pre-dispensed
Slovenian: EXUBERA 1 mg prašek za inhaliranje, odmerjen EXUBERA 3 mg prašek za inhaliranje, odmerjen humani insulin
English: Dose adjustments may be required based on meal size and nutrient composition, time of day (higher insulin requirements in the morning), pre-meal blood glucose concentration, recent or planned
Slovenian: Glede na velikost obrokov in sestavo hranil, dnevni čas (večja potreba po insulinu zjutraj), koncentracijo glukoze pred obroki ter nedavno ali načrtovano telesno dejavnost utegnejo biti potrebne prilagoditve odmerka.
English: In obese subjects with type 2 diabetes, intrasubject variability was comparable to or less than that of subcutaneously administered fast-acting human insulin for Cmax and AUC.
Slovenian: Pri debelih preiskovancih z diabetesom tipa 2 je bila intraindividualna variabilnost Cmax in AUC primerljiva ali manjša kot subkutano apliciranega hitrodelujočega humanega insulina.
English: Fasting plasma glucose levels were significantly lower in patients treated with regimens including EXUBERA compared with those treated with subcutaneously administered fast-acting human insulin only regimens.
Slovenian: Koncentracije plazemske glukoze na tešče so bile pomembno nižje pri bolnikih, zdravljenih s shemami z zdravilom EXUBERA, kot pri bolnikih, zdravljenih s shemami, ki so obsegale samo subkutano injicirani hitrodelujoči humani insulin.
English: While holding the IRU with one hand, turn the top counter-clockwise as
Slovenian: Z eno roko držite nastavek za sproščanje insulina in zasukajte vrh v smeri, nasprotni od smeri urnega kazalca, kolikor
English: Please see the end of section 4 for important information about hypoglycaemia and hyperglycaemia
Slovenian: Za pomembne nadaljnje informacije o hipoglikemji in hiperglikemiji ter njunem zdravljenju glejte zadnji del poglavja 4.
English: Therefore three 1 mg unit dose blisters should not be substituted for one 3 mg unit dose blister (see sections 2, 4.2 and 5.2).
Slovenian: Zato se enega 3mg pretisnega omota za enkratni odmerek ne sme nadomestiti s tremi 1-mg (glejte poglavja 2, 4.2 in
English: Allow to air dry.
Slovenian: Pustite komoro in ustnik, da se posušita na zraku.
English: There is very little experience with EXUBERA in patients with congestive heart failure.
Slovenian: Pri bolnikih s kongestivnim srčnim popuščanjem imamo zelo malo izkušenj z zdravilom EXUBERA.
English: Your blood sugar level may either fall or rise if you take beta-blockers or drink alcohol.
Slovenian: Če jemljete zaviralce adrenergičnih receptorjev beta ali pijete alkohol, se lahko koncentracija vašega krvnega sladkorja bodisi zniža bodisi zviša.
English: a) The need for consistent and standard inhalation technique to ensure both optimal and consistent b) Special precaution with the insulin inhaler d) 1 mg and 3 mg dose inequivalence e) Magnitude of titration steps and resulting precautions f) The change in pulmonary function and the need for pulmonary function monitoring g) Smoking in relation to induced alteration in pharmacokinetics i) Increased insulin antibody levels j) Recommendation for special populations; underlying lung diseases such as asthma and COPD,
Slovenian: e) velikosti titracijskih korakov in posledičnih previdnostnih ukrepih, f) spremembah delovanja pljuč in potrebi po nadziranju pljučnega delovanja, g) kajenju v zvezi s povzročenimi spremembami farmakokinetike,
English: Therefore, EXUBERA should not be used during pregnancy.
Slovenian: Zato zdravila EXUBERA v nosečnosti ni dovoljeno uporabljati.
English: Check with your doctor, nurse or pharmacist if you have any questions regarding EXUBERA or the insulin inhaler.
Slovenian: Če imate kakšna vprašanja glede zdravila EXUBERA ali glede insulinskega inhalatorja, se obrnite na svojega zdravnika, medicinsko sestro ali farmacevta.
English: In clinical trials in type 1 diabetes, patients using a regimen of EXUBERA in combination with longor intermediate-acting insulin had similar reductions in HbA1c compared with patients taking subcutaneous insulin alone.
Slovenian: Pri kliničnih preskušanjih pri diabetesu tipa 1 je bilo znižanje HbA1c podobno pri bolnikih, ki so se zdravili s shemo z zdravilom EXUBERA v kombinaciji z dolgo- ali srednjedolgo- delujočim insulinom, in pri bolnikih, ki so se zdravili samo s subkutanim insulinom.
English: Inhaled human insulin has a duration of glucose lowering activity comparable to subcutaneously administered fast-acting human insulin and longer than fast-acting insulin analogues (see Figure 1).
Slovenian: Trajanje aktivnosti zniževanja glukoze pri humanem insulinu za inhaliranje je primerljivo kot pri subkutano injiciranem hitrodelujočem humanem insulinu in daljše kot pri hitrodelujočih analogih insulina (glejte