FrancophonIA/ELRC3.0 huggingface dataset:
English: Once diluted, the solution of PREVYMIS is clear, and ranges from colourless to yellow.
Danish: Efter fortynding er infusionsvæsken med PREVYMIS klar og farveløs til gul i udseende.
English: PREVYMIS concentrate for solution for infusion is a clear, colourless solution.
Danish: Prevymis koncentrat til infusionsvæske, opløsning, er en klar, farveløs opløsning.
English: Frequent monitoring of tacrolimus whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of tacrolimus adjusted accordingly tacrolimus (5 mg single dose)/ letermovir (80 mg twice daily)
Danish: Der bør foretages hyppig monitorering af tacrolimuskoncentrationen i fuldblod under behandlingen, ved skift af administrationsvej for PREVYMIS og ved seponering af PREVYMIS, og tacrolimus-dosis skal justeres i overensstemmelse hermed tacrolimus (5 mg enkeltdosis)/ letermovir (80 mg to gange dagligt)
English: Yellow oval tablet of dimensions 16.5 mm x 8.5 mm, debossed with “591” on one side and MSD logo on the other side.
Danish: Gul oval tablet, 16,5 mm x 8,5 mm, præget med “591” på den ene side og MSD-logo på den anden side.
English: The 240 mg and 480 mg concentrate for solution for infusion is packaged in clear, glass vials.
Danish: 240 mg og 480 mg koncentratet til infusionsvæske, opløsning, leveres i hætteglas af klart glas.
English: PREVYMIS 240 mg film-coated tablet is a yellow oval tablet, debossed with “591” on one side and MSD logo on the other side.
Danish: Prevymis 240 mg filmovertrukken tablet er en gul oval tablet præget med “591” på den ene side og MSD-logo på den anden side.
English: Bone marrow (n=72, 43)
Danish: Knoglemarv (n=72, 43)
English: Musculoskeletal and connective tissue disorders Uncommon muscle spasms
Danish: Knogler, led, muskler og bindevæv Ikke almindelig muskelkramper
English: Each 480 mg film-coated tablet contains less than 1 mmol sodium (23 mg).
Danish: Hver 480 mg filmovertrukken tablet indeholder mindre end 1 mmol natrium (23 mg).
English: If letermovir is co-administered with cyclosporine, the recommended dose of letermovir is 240 mg once daily (see section 4.2).
Danish: Hvis letermovir administreres samtidigt med ciclosporin, er den anbefalede dosis af letermovir 240 mg en gang dagligt (se pkt.
English: ↓ voriconazole AUC 0.56 (0.51, 0.62) Cmax 0.61 (0.53, 0.71)
Danish: ↓ voriconazol AUC 0,56 (0,51; 0,62) Cmax 0,61 (0,53; 0,71)
English: • Ampicillin sodium/Sulbactam sodium • Human insulin
Danish: • Ampicillinnatrium/sulbactamnatrium •
English: When PREVYMIS is co-administered with cyclosporine, refer also to the glyburide prescribing information for specific dosing recommendations.
Danish: Ved administration af PREVYMIS sammen med ciclosporin henvises også til produktresuméet for glyburid for specifikke doseringsanbefalinger.
English: • Add one single-dose vial of (either 12 mL (240 mg dose) or 24 mL (480 mg dose)) of PREVYMIS concentrate for solution for infusion to a 250 mL pre-filled IV bag containing either 0.9% sodium chloride or 5% dextrose, and mix the diluted solution by gentle inversion.
Danish: • Tilsæt et enkeltdosis-hætteglas (enten 12 ml (240 mg dosis) eller 24 ml (480 mg dosis)) med Prevymis koncentrat til infusionsvæske, opløsning, til en 250 ml fyldt intravenøs infusionspose, der indeholder enten 0,9 % natriumchlorid eller 5 % glucose, og bland den fortyndede infusionsvæske ved forsigtigt at vende infusionsposen.
English: Frequent monitoring of cyclosporine whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of cyclosporine adjusted accordingly cyclosporine (200 mg single dose)/ letermovir (240 mg daily)
Danish: Der bør foretages hyppig monitorering af ciclosporinkoncentrationen i fuldblod under behandlingen, ved skift af administrationsvej for PREVYMIS og ved seponering af PREVYMIS, og ciclosporin-dosis skal justeres i overensstemmelse hermed ciclosporin (200 mg enkeltdosis)/ letermovir (240 mg dagligt)
English: PREVYMIS concentrate for solution for infusion must be diluted prior to intravenous use.
Danish: Prevymis koncentrat til infusionsvæske, opløsning, skal fortyndes før intravenøs anvendelse.
English: If a vial is added to a 250 mL IV diluent bag, the final concentration ranges of letermovir would be 0.9 mg/mL (for 240 mg dose) and 1.8 mg/mL (for 480 mg dose).
Danish: Hvis et hætteglas tilsættes en 250 ml intravenøs infusionspose med diluent, vil den endelige koncentration af letermovir ligge på omtrent 0,9 mg/ml (for dosis på 240 mg) og 1,8 mg/ml (for dosis på 480 mg).
English: Other medicines and PREVYMIS
Danish: Brug af anden medicin sammen med Prevymis
English: When PREVYMIS is co-administered with cyclosporine, the plasma concentrations of repaglinide is expected to increase due to the additional OATP1B inhibition by cyclosporine.
Danish: Ved administration af PREVYMIS sammen med ciclosporin forventes plasmakoncentrationen af repaglinid at stige som følge af yderligere OATP1Bhæmning af ciclosporin.
English: What you need to know before you take PREVYMIS 3.
Danish: Det skal du vide, før du begynder at tage Prevymis 3.
English: Mismatched unrelated (n=43, 24)
Danish: Mismatch ubeslægtet (n=43, 24)
English: PREVYMIS 240 mg concentrate for solution for infusion contains 23 mg (or 1.0 mmol) sodium per dose.
Danish: PREVYMIS 240 mg koncentrat til infusionsvæske, opløsning, indeholder 23 mg (eller 1,0 mmol) natrium pr. dosis.
English: If you also take cyclosporine, your doctor will decrease the dose of PREVYMIS to one 240 mg tablet once a day.
Danish: Hvis du også tager ciclosporin, vil lægen nedsætte dosis af Prevymis til en 240 mg tablet en gang dagligt.
English: Each 240 mg film-coated tablet contains less than 1 mmol sodium (23 mg).
Danish: Hver 240 mg filmovertrukken tablet indeholder mindre end 1 mmol natrium (23 mg).
English: This medicinal product contains 23 mg (1.0 mmol) sodium per 240 mg vial, equivalent to 1.15% of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Danish: Hjælpestof, som behandleren skal være opmærksom på Dette lægemiddel indeholder 23 mg (1,0 mmol) natrium pr. 240 mg hætteglas, svarende til 1,15 % af WHO's anbefalede maksimale daglige indtag af natrium på 2 g for voksne.
English: Expected: ↔ letermovir
Danish: Forventet: ↓ letermovir
English: Expected: ↓ letermovir
Danish: Forventet: ↔ letermovir
English: If you take more PREVYMIS than you should If you take more PREVYMIS than you should, call your doctor straight away.
Danish: Hvis du har taget for meget Prevymis Hvis du har taget for meget Prevymis, skal du straks kontakte lægen.
English: (CYP2C9/19 induction)
Danish: (CYP2C9/19-induktion)
English: Co-administration of PREVYMIS with these antivirals is not recommended.
Danish: Samtidig administration af PREVYMIS og disse antivirale midler anbefales ikke.
English: PREVYMIS should not be co-administered through the same intravenous line (or cannula) with other medicinal products and diluent combinations except those listed below.
Danish: PREVYMIS må ikke administreres samtidigt med andre kombinationer af lægemidler og diluenter i samme infusionsslange (eller kanyle) end de nedenfor anførte.
English: If it is time for the next dose, skip the missed dose and go back to the regular schedule.
Danish: Hvis det er tid til den næste dosis, skal den glemte dosis springes over, og det normale doseringsskema skal følges igen.
English: PREVYMIS 480 mg film-coated tablet is a pink oval, bi-convex tablet, debossed with “595” on one side and MSD logo on the other side.
Danish: Prevymis 480 mg filmovertrukken tablet er en pink oval, bikonveks tablet præget med “595” på den ene side og MSD-logo på den anden side.
English: o St. John's wort (Hypericum perforatum)
Danish: Naturlægemidler perikon (Hypericum perforatum)
English: Carbamazepine or phenobarbital may decrease plasma concentrations of letermovir.
Danish: Carbamazepin eller phenobarbital kan nedsætte plasmakoncentrationen af letermovir.
English: Concomitant use is not recommended with PREVYMIS alone.
Danish: Samtidig administration anbefales ikke med PREVYMIS alene.
English: When PREVYMIS is co-administered with cyclosporine, the magnitude of the increase in concentrations of sirolimus may be greater than with PREVYMIS alone.
Danish: Ved administration af PREVYMIS sammen med ciclosporin kan stigningen i sirolimuskoncentrationen være højere end med PREVYMIS alene.
English: Add one single-dose vial (either 12 mL (240 mg dose) or 24 mL (480 mg dose)) of PREVYMIS concentrate for solution for infusion to a 250 mL pre-filled IV bag containing either 0.9% sodium chloride or 5% dextrose, and mix the diluted solution by gentle inversion.
Danish: Tilsæt et enkeltdosis-hætteglas (enten 12 ml (240 mg dosis) eller 24 ml (480 mg dosis)) med PREVYMIS koncentrat til infusionsvæske, opløsning, til en 250 ml fyldt intravenøs infusionspose, der indeholder enten 0,9 % natriumchlorid eller 5 % glucose, og bland den fortyndede infusionsvæske ved forsigtigt at vende infusionsposen.
English: The 480 mg tablets are packaged into a carton containing four (4) cardboard cards, each containing a 7-count Polyamide/Aluminium/PVC - Aluminium blister card for a total of 28 tablets.
Danish: 480 mg tabletterne er pakket i en karton, der indeholder fire (4) papomslag, som hver indeholder et polyamid/aluminium/PVC - aluminiumblisterkort med 7 tabletter, hvilket giver 28 tabletter i alt.
English: The active substance is letermovir.
Danish: Prevymis indeholder: - Aktivt stof: letermovir.
English: Do not throw away any medicines via wastewater.
Danish: Af hensyn til miljøet må du ikke smide medicinrester i afløbet eller toilettet.
English: Cardiovascular medicinal products digoxin (0.5 mg single dose)/ letermovir (240 mg twice daily)
Danish: Kardiovaskulære lægemidler digoxin (0,5 mg enkeltdosis)/ letermovir (240 mg to gange dagligt)
English: 240 mg Oral, with cyclosporine
Danish: 240 mg oralt, med ciclosporin
English: Irreversible testicular toxicity and impairment of fertility was observed in male rats, but not in male mice or male monkeys.
Danish: Der blev observeret irreversibel testikeltoksicitet og nedsat fertilitet hos hanrotter, men ikke hos hanmus eller hanaber.
English: How to take PREVYMIS 4.
Danish: Sådan skal du tage Prevymis 4.
English: • Ceftaroline
Danish: • Ceftarolin
English: (CYP3A, OATP1B1/3 inhibition)
Danish: (CYP3A-, OATP1B1/3-hæmning)
English: Letermovir may increase the plasma concentrations of quinidine.
Danish: Letermovir kan øge plasmakoncentrationerne af quinidin.
English: Immunosuppressants cyclosporine (50 mg single dose)/ letermovir (240 mg daily)
Danish: Immunsuppressiva ciclosporin (50 mg enkeltdosis)/ letermovir (240 mg dagligt)
English: The 240 mg tablets are packaged into a carton containing four (4) cardboard cards, each containing a 7-count Polyamide/Aluminium/PVC - Aluminium blister card for a total of 28 tablets.
Danish: 240 mg tabletterne er pakket i en karton, der indeholder fire (4) papomslag, som hver indeholder et polyamid/aluminium/PVC - aluminiumblisterkort med 7 tabletter, hvilket giver 28 tabletter i alt.
English: Catheters Radiopaque polyurethane
Danish: Katetre Røntgenfast polyurethan.
English: PO:
Danish: NN:
English: If you also take cyclosporine, your doctor will decrease the dose of PREVYMIS to 240 mg once a day.
Danish: Hvis du også tager ciclosporin, vil lægen nedsætte dosis af Prevymis til 240 mg en gang dagligt.
English: ↔ posaconazole AUC 0.98 (0.82, 1.17) Cmax 1.11 (0.95, 1.29)
Danish: ↔ posaconazol AUC 0,98 (0,82; 1,17) Cmax 1,11 (0,95; 1,29)
English: (Sum of OATP1B1/3 and/or Pgp inhibition and P-gp/UGT induction)
Danish: (Summen af OATP1B1/3 og/eller P-gp-hæmning og P-gp/UGTinduktion)
English: Inhibitors of P-gp/BCRP
Danish: Pg-p-/BCRP-hæmmere
English: What you need to know before you take PREVYMIS
Danish: Det skal du vide, før du begynder at tage Prevymis
English: Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicinal product.
Danish: PREVYMIS indeholder lactosemonohydrat og bør ikke anvendes til patienter med arvelig galactoseintolerans, en særlig form af hereditær lactasemangel (Lapp lactase deficiency) eller glucose/galactosemalabsorption.
English: • Ceftriaxone sodium
Danish: • Ceftriaxonnatrium
English: Co-administration of PREVYMIS and phenytoin is not recommended.
Danish: Samtidig administration af PREVYMIS og phenytoin anbefales ikke.
English: Co-administration of PREVYMIS and nafcillin is not recommended.
Danish: Samtidig administration af PREVYMIS og nafcillin anbefales ikke.
English: How you are given PREVYMIS
Danish: Sådan får du Prevymis
English: Increased monitoring of cyclosporine, tacrolimus, sirolimus is generally recommended the first 2 weeks after initiating and ending letermovir (see section 4.5) as well as after changing route of administration of letermovir.
Danish: Øget monitorering af ciclosporin, tacrolimus, sirolimus anbefales generelt i løbet af de første 2 uger efter initiering og afslutning af behandling med letermovir (se pkt.
English: voriconazole (200 mg twice daily)/ letermovir (480 mg daily)
Danish: voriconazol (200 mg to gange dagligt)/ letermovir (480 mg dagligt)
English: The anticipated clinical exposure to hydroxypropylbetadex with intravenously administered letermovir is expected to be approximately 3600 mg/day for a letermovir dose of 480 mg.
Danish: Den forventede kliniske eksponering for hydroxypropylbetadex med intravenøst administreret letermovir forventes at være ca. 3.600 mg/dag for en letermovir-dosis på 480 mg. Der var ingen tilfælde af nyreskade forårsaget af hydroxypropylbetadex i studier hos mennesker, der modtog letermovir intravenøst med behandlingsvarigheder på op til 47 dage.
English: Letermovir is an inhibitor of OATP1B1/3 transporters.
Danish: Letermovir hæmmer OATP1B1/3-transportører.
English: Incompatible intravenous bags and infusion set materials PREVYMIS concentrate for solution for infusion is incompatible with polyurethane-containing IV administration set tubing.
Danish: Inkompatible intravenøse infusionsposer og infusionssæt Prevymis koncentrat til infusionsvæske, opløsning, er inkompatibelt med infusionssæt med slanger, der indeholder polyurethan.
English: (likely due to induction of CYP2C19)
Danish: (sandsynligvis pga. CYP2C19induktion)
English: 480 mg Oral, no cyclosporine
Danish: 480 mg oralt, uden ciclosporin
English: ↔mycophenolic acid AUC 1.08 (0.97, 1.20) Cmax 0.96 (0.82, 1.12)
Danish: ↔ mycophenolsyre AUC 1,08 (0,97; 1,20) Cmax 0,96 (0,82; 1,12)
English: Letermovir may increase the plasma concentrations of amiodarone.
Danish: Letermovir kan øge plasmakoncentrationen af amiodaron.
English: Each film-coated tablet contains 240 mg letermovir or 480 mg letermovir.
Danish: Hver filmovertrukken tablet indeholder 240 mg letermovir eller 480 mg letermovir.
English: Favors Letermovir
Danish: Til fordel for letermovir
English: Letermovir may increase the plasma concentrations of glyburide.
Danish: Letermovir kan øge plasmakoncentrationerne af glyburid.
English: No dose adjustment required.
Danish: Dosisjustering er ikke nødvendig.
English: Concomitant administration with pimozide (see sections 4.4 and 4.5).
Danish: Administration sammen med pimozid (se pkt.
English: Administration of PREVYMIS may result in a clinically relevant increase in plasma concentrations of co-administered medicinal products that are OATP1B1/3 substrates.
Danish: Administration af PREVYMIS og substrater for OATP1B1/3-transportører kan resultere i en klinisk relevant stigning i plasmakoncentrationen af de samtidigt administrerede OATP1B1/3-substrater.
English: These antivirals may decrease plasma concentration of letermovir.
Danish: Disse antivirale midler kan nedsætte plasmakoncentrationen af letermovir.
English: Co-administration of PREVYMIS and bosentan is not recommended.
Danish: Samtidig administration af PREVYMIS og bosentan anbefales ikke.
English: PREVYMIS 480 mg concentrate for solution for infusion Each vial contains 480 mg (24 mL per vial) of letermovir.
Danish: PREVYMIS 480 mg koncentrat til infusionsvæske, opløsning Hvert hætteglas indeholder 480 mg (24 ml pr. hætteglas) letermovir.
English: Coadministration of PREVYMIS may result in clinically relevant increases in the plasma concentrations of co-administered CYP3A substrates (see sections 4.3, 4.4, and 5.2).
Danish: Samtidig administration af PREVYMIS kan resultere i en klinisk relevant stigning i plasmakoncentrationen af de samtidigt administrerede CYP3A-substrater (se pkt.
English: PREVYMIS 240 mg concentrate for solution for infusion Each vial contains 240 mg (12 mL per vial) of letermovir.
Danish: PREVYMIS 240 mg koncentrat til infusionsvæske, opløsning Hvert hætteglas indeholder 240 mg (12 ml pr. hætteglas) letermovir.
English: PREVYMIS contains sodium
Danish: Prevymis indeholder natrium
English: posaconazole (300 mg single dose)/ letermovir (480 mg daily)
Danish: posaconazol (300 mg enkeltdosis)/ letermovir (480 mg dagligt)
English: Each 480 mg dose (24 mL vial) of this medicine contains 3600 mg cyclodextrin.
Danish: Hver 480 mg dosis (24 ml hætteglas) af dette lægemiddel indeholder 3.600 mg cyclodextrin.
English: If you are not sure, talk to your doctor, pharmacist or nurse before you are given PREVYMIS.
Danish: Hvis du er i tvivl, så kontakt lægen, apotekspersonalet eller sundhedspersonalet, før du får behandling med Prevymis.
English: PREVYMIS contains sodium.
Danish: Prevymis indeholder natrium.
English: Each 480 mg dose (24 mL vial) of this medicinal product contains 3600 mg hydroxypropylbetadex (cyclodextrin).
Danish: Hver 480 mg dosis (24 ml hætteglas) af dette lægemiddel indeholder 3.600 mg hydroxypropylbetadex (cyclodextrin).
English: Medicinal products transported by P-gp in the intestine Letermovir is an inducer of intestinal P-gp.
Danish: Letermovir er en induktor af intestinal P-gp.
English: Each 240 mg dose (12 mL vial) of this medicinal product contains 1800 mg hydroxypropylbetadex (cyclodextrin).
Danish: Hver 240 mg dosis (12 ml hætteglas) af dette lægemiddel indeholder 1.800 mg hydroxypropylbetadex (cyclodextrin).
English: Letermovir may decrease the plasma concentrations of phenytoin.
Danish: Letermovir kan nedsætte plasmakoncentrationerne af phenytoin.
English: Co-administration of PREVYMIS and thioridazine is not recommended.
Danish: Samtidig administration af PREVYMIS og thioridazin anbefales ikke.
English: HMG-CoA reductase inhibitors atorvastatin (20 mg single dose)/ letermovir (480 mg daily)
Danish: HMG-CoA-reduktasehæmmere atorvastatin (20 mg enkeltdosis)/ letermovir (480 mg dagligt)
English: PREVYMIS 240 mg sterile concentrate letermovir
Danish: PREVYMIS 240 mg sterilt koncentrat letermovir
English: Microcrystalline cellulose (E460) Croscarmellose sodium (E468) Povidone (E1201) Colloidal anhydrous silica (E551) Magnesium stearate (E470b)
Danish: Mikrokrystallinsk cellulose (E460) Croscarmellosenatrium (E468) Povidon (E1201)
English: Antifungals fluconazole (400 mg single dose)/letermovir (480 mg single dose)
Danish: Antimykotika fluconazol (400 mg enkeltdosis)/letermovir (480 mg enkeltdosis)
English: Letermovir may decrease the plasma concentrations of warfarin.
Danish: Letermovir kan nedsætte plasmakoncentrationerne af warfarin.
English: Concomitant administration with ergot alkaloids: (see sections 4.4 and 4.5).
Danish: Administration sammen med sekalealkaloider (se pkt.
English: Refer to the respective prescribing information (see section 4.4).
Danish: Se det tilhørende produktresumé (se pkt.
English: Each 240 mg dose (12 mL vial) of this medicine contains 1800 mg cyclodextrin.
Danish: Hver 240 mg dosis (12 ml hætteglas) af dette lægemiddel indeholder 1.800 mg cyclodextrin.
English: Co-administration of PREVYMIS and nevirapine is not recommended.
Danish: Samtidig administration af PREVYMIS og nevirapin anbefales ikke.
English: 240 mg IV, with cyclosporine
Danish: 240 mg intravenøst, med ciclosporin
English: Each film-coated tablet contains 240 mg of letermovir.
Danish: Hver filmovertrukken tablet indeholder 240 mg letermovir.
English: PREVYMIS 480 mg sterile concentrate letermovir
Danish: PREVYMIS 480 mg sterilt koncentrat letermovir
English: tacrolimus (5 mg single dose)/ letermovir (480 mg daily)
Danish: tacrolimus (5 mg enkeltdosis)/ letermovir (480 mg dagligt)
English: Each film-coated tablet contains 480 mg of letermovir.
Danish: Hver filmovertrukken tablet indeholder 480 mg letermovir.
English: Infusion set materials
Danish: Infusionssæt fremstillet af
English: (CYP2C9 induction)
Danish: (CYP2C9-induktion)
English: Co-administration of PREVYMIS and modafinil is not recommended.
Danish: Samtidig administration af PREVYMIS og modafinil anbefales ikke.
English: You should not be given PREVYMIS if:
Danish: Du må ikke få Prevymis:
English: PREVYMIS 480 mg tablets letermovir
Danish: PREVYMIS 480 mg tabletter letermovir
English: ↑ tacrolimus AUC 2.42 (2.04, 2.88) Cmax 1.57 (1.32, 1.86) (CYP3A inhibition)
Danish: ↑ tacrolimus AUC 2,42 (2,04; 2,88) Cmax 1,57 (1,32; 1,86)
English: • Hydrocortisone sodium succinate
Danish: Hydrocortisonnatriumsuccinat
English: After uptake, glucuronidation of letermovir is mediated by UGT1A1 and 3.
Danish: Efter optagelsen medierer UGT1A1 og 3 glucuronidering af letermovir.
English: Co-administration of PREVYMIS and rifampicin is not recommended.
Danish: Samtidig administration af PREVYMIS og rifampicin anbefales ikke.
English: (OATP1B1/3 inhibition)
Danish: (OATP1B1/3-hæmning)
English: mycophenolate mofetil (1 g single dose)/ letermovir (480 mg daily)
Danish: mycophenolatmofetil (1 g enkeltdosis)/ letermovir (480 mg dagligt)
English: Co-administration of PREVYMIS and rifabutin is not recommended.
Danish: Samtidig administration af PREVYMIS og rifabutin anbefales ikke.
English: PREVYMIS 240 mg concentrate for solution for infusion PREVYMIS 480 mg concentrate for solution for infusion
Danish: PREVYMIS 240 mg koncentrat til infusionsvæske, opløsning PREVYMIS 480 mg koncentrat til infusionsvæske, opløsning
English: Outer carton for 480 mg film-coated tablets
Danish: Ydre karton til 480 mg filmovertrukne tabletter
English: PREVYMIS 240 mg tablets letermovir
Danish: PREVYMIS 240 mg tabletter letermovir
English: ↔ acyclovir AUC 1.02 (0.87, 1.2) Cmax 0.82 (0.71, 0.93)
Danish: ↔ aciclovir AUC 1,02 (0,87; 1,2) Cmax 0,82 (0,71; 0,93)
English: (OATP1B1/3 and/or P-gp inhibition)
Danish: (OATP1B1/3 og/eller P-gphæmning)
English: Blister for 240 mg film-coated tablets
Danish: Blister til 240 mg filmovertrukne tabletter
English: When PREVYMIS is co-administered with cyclosporine, pravastatin is not recommended while for fluvastatin, a dose reduction may be necessary
Danish: Ved administration af PREVYMIS sammen med ciclosporin frarådes pravastatin, mens en dosisreduktion af fluvastatin kan være nødvendig Statinrelaterede bivirkninger, f.eks. myopati, bør monitoreres nøje.
English: Sedatives midazolam (1 mg single dose IV)/ letermovir (240 mg once daily PO)
Danish: Sedativa midazolam (1 mg intravenøs enkeltdosis)/ letermovir (240 mg oralt en gang dagligt)
English: PREVYMIS 240 mg concentrate for solution for infusion PREVYMIS 480 mg concentrate for solution for infusion letermovir
Danish: Prevymis 240 mg koncentrat til infusionsvæske, opløsning Prevymis 480 mg koncentrat til infusionsvæske, opløsning letermovir
English: sirolimus (2 mg single dose)/ letermovir (480 mg daily)
Danish: sirolimus (2 mg enkeltdosis)/ letermovir (480 mg dagligt)
English: midazolam (2 mg single dose PO) / letermovir (240 mg once daily PO)
Danish: midazolam (2 mg oral enkeltdosis)/ letermovir (240 mg oralt en gang dagligt)
English: Outer carton for 240 mg film-coated tablets
Danish: Ydre karton til 240 mg filmovertrukne tabletter
English: Blister for 480 mg film-coated tablets
Danish: Blister til 480 mg filmovertrukne tabletter
English: MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE
Danish: Navn og adresse på den fremstiller, der er ansvarlig for batchfrigivelse