FrancophonIA/ELRC3.0 huggingface dataset:
English: LIST OF EXCIPIENTS Also contains aspartame (E951) and methyl parahydroxybenzoate (E218).
Slovenian: SEZNAM POMOŽNIH SNOVI Med pomožnimi snovmi sta tudi aspartam (E951) in metilparahidroksibenzoat (E218).
English: Other medicines and CellCept
Slovenian: Druga zdravila in zdravilo CellCept
English: An estimated total of 1268 patients received CellCept during four clinical trials in the prevention of acute organ rejection.
Slovenian: Ocenili so, da je zdravilo CellCept prejemalo skupno 1268 bolnikov v štirih kliničnih preskušanjih preprečevanja akutne zavrnitve presajenega organa.
English: Turn the whole thing back round the right way.
Slovenian: Steklenico in razdelilnik skupaj obrnite pravilno nazaj.
English: If you are planning to become pregnant or if you get pregnant while you or your partner are taking CellCept.
Slovenian: • če nameravate zanositi ali zanosite v času, ko vi ali vaš partner jemlje zdravilo CellCept.
English: In renal transplant patients with severe chronic renal impairment (glomerular filtration rate < 25 mL/min/1.73 m2), outside the immediate post-transplant period, doses greater than 1 g administered twice a day should be avoided.
Slovenian: Bolnikom s hudo kronično ledvično okvaro (glomerulna filtracija < 25 ml/min/1,73 m2) izven obdobja neposredno po presaditvi ne dajemo odmerkov, večjih od 1 g dvakrat na dan.
English: Take 2 tablets in the morning and then 2 tablets in the evening.
Slovenian: • Vzemite 2 tableti zjutraj in 2 tableti zvečer.
English: • CellCept should not be given to patients with hypersensitivity to mycophenolate mofetil, mycophenolic acid or to any of the excipients listed in section 6.1.
Slovenian: • Zdravila Cellcept ne smemo uporabljati pri bolnikih s preobčutljivostjo za mofetilmikofenolat, mikofenolno kislino ali katero koli pomožno snov, navedeno v poglavju 6.1.
English: CellCept has a moderate influence on the ability to drive and use machines.
Slovenian: Zdravilo CellCept ima zmeren vpliv na sposobnost vožnje in upravljanja strojev.
English: * contains phenylalanine equivalent to 2.78 mg/5 mL of suspension.
Slovenian: * Vsebuje 2,78 mg fenilalanina v 5 ml suspenzije.
English: PRCA may resolve with dose reduction or cessation of CellCept therapy.
Slovenian: PRCA je lahko reverzibilna z zmanjšanjem odmerka ali s prekinitvijo zdravljenja z zdravilom CellCept.
English: • fluid on the lungs or inside the chest,
Slovenian: • tekočina v pljučih ali prsih,
English: • Take 7.5 mL suspension in the morning and then 7.5 mL suspension in the evening.
Slovenian: • Vzemite 7,5 ml suspenzije zjutraj in 7,5 ml suspenzije zvečer.
English: Take care not to let any powder from inside a broken capsule get into your eyes or mouth.
Slovenian: Bodite previdni, da prašek, ki ga vsebujejo poškodovane kapsule, ne pride v oči ali usta.
English: An estimated total of 1557 patients received CellCept during five clinical trials in the prevention of acute organ rejection.
Slovenian: Ocenili so, da je zdravilo CellCept prejemalo skupno 1557 bolnikov v petih kliničnih preskušanjih preprečevanja akutne zavrnitve presajenega organa.
English: CellCept tablets: lavender coloured caplet-shaped tablet, engraved with "CellCept 500" on one side and "ROCHE" name on the other.
Slovenian: CellCept tablete: svetlo vijoličaste barve, ovalne oblike, z vgraviranim napisom “CellCept 500” na eni strani in imenom “ROCHE” na drugi.
English: What you need to know before you take CellCept
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo CellCept
English: METHOD OF ADMINISTRATION For intravenous infusion only Read the package leaflet before use
Slovenian: POSTOPEK UPORABE Samo za intravensko infuzijo Pred uporabo preberite priloženo navodilo
English: • If you are allergic (hypersensitive) to mycophenolate mofetil, mycophenolic acid or any of the other ingredients in this medicine (listed in Section 6)
Slovenian: • če ste alergični (preobčutljivi) na mofetilmikofenolat, mikofenolno kislino, polisorbat 80 ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
English: The pharmacokinetics of mycophenolate mofetil and its metabolites have not been found to be altered in the elderly patients (≥ 65 years) when compared to younger patients.
Slovenian: Ugotovili so, da farmakokinetika mofetilmikofenolata in njegovih presnovkov pri starejših bolnikih (≥ 65 let) s presadki v primerjavi z mlajšimi bolniki s presadki ni spremenjena.
English: 1 carton contains 100 capsules (in blister packs of 10) 1 carton contains 300 capsules (in blister packs of 10)
Slovenian: 1 škatla s 100 kapsulami (v pretisnih omotih po 10 kapsul) 1 škatla s 300 kapsulami (v pretisnih omotih po 10 kapsul)
English: The shelf-life of the powder for oral suspension is 2 years.
Slovenian: Rok uporabnosti praška za peroralno suspenzijo je 2 leti.
English: Patients should be advised that during treatment with CellCept, vaccinations may be less effective, and the use of live attenuated vaccines should be avoided (see section 4.5).
Slovenian: Bolnike, ki prejemajo zdravilo CellCept, moramo opozoriti, da so lahko cepiva manj učinkovita, uporabi živih cepiv pa se morajo izogibati (glejte poglavje 4.5).
English: A bottle adapter and 2 oral dispensers are also provided.
Slovenian: V ovojnini sta dodana tudi nastavek za steklenico in 2 peroralna razdelilnika.
English: OTHER SPECIAL WARNING(S), IF NECESSARY CellCept film-coated tablets should be handled with care Do not crush the tablets
Slovenian: DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA CellCept filmsko obložene tablete je treba uporabljati previdno Tablet ne drobite
English: Cardiac transplant n = 289
Slovenian: Presaditev srca n = 289
English: • septum pellucidum agenesis;
Slovenian: • agenezija septuma pelluciduma,
English: What CellCept looks like and contents of the pack
Slovenian: Izgled zdravila CellCept in vsebina pakiranja
English: Take 3 tablets in the morning and then 3 tablets in the evening.
Slovenian: • Vzemite 3 tablete zjutraj in 3 tablete zvečer.
English: Counselling of patients: This section will emphasise the importance of a thorough, informative and ongoing dialogue between patient and healthcare professional about the pregnancy risks associated with mycophenolate mofetil and the relevant minimisation strategies including alternative treatment choices, if applicable.
Slovenian: To poglavje bo poudarilo pomembnost temeljitega, poučnega in stalnega pogovora med bolnikom in zdravstvenim delavcem o tveganju uporabe mofetilmikofenolata med nosečnostjo in ustreznih strategijah za njegovo zmanjševanje, vključno z drugimi možnostmi zdravljenja, če so primerne.
English: • They are available as packs of 50 (in blister packs of 10) or Multipacks containing 150 (3 packs of 50) tablets.
Slovenian: • Na voljo so v pakiranjih s 50 (pretisni omoti po 10) ali v skupnih pakiranjih s 150 (3 škatle po
English: CellCept is used to prevent your body rejecting a transplanted organ.
Slovenian: Zdravilo CellCept prepreči, da bi vaše telo zavrnilo presadek.
English: Patients treated with immunosuppressants, including CellCept, are at increased risk for opportunistic infections (bacterial, fungal, viral and protozoal), fatal infections and sepsis (see section 4.8).
Slovenian: Bolniki, ki se zdravijo z imunosupresivi, vključno z zdravilom CellCept, imajo povečano tveganje za oportunistične okužbe (bakterijske, glivične, virusne in protozojske), smrtne okužbe in sepso (glejte poglavje 4.8).
English: • If you are a woman who could be pregnant and you have not provided a negative pregnancy test before your first prescription as mycophenolate causes birth defects and miscarriage.
Slovenian: • če ste bolnica, ki bi lahko bila noseča, in pred prvim predpisanim receptom nimate potrjenega negativnega testa nosečnosti, saj lahko mofetilmikofenolat povzroči prirojene okvare in spontani splav,
English: A detailed description of the preparation is given below:
Slovenian: Podroben opis priprave je podan spodaj: Korak 1
English: As can happen in patients taking this type of medicine (immune-suppressants), a very small number of CellCept patients have developed cancer of the lymphoid tissues and skin.
Slovenian: Kot se lahko zgodi pri bolnikih, ki jemljejo takšno vrsto zdravil (zdravila za zaviranje imunske odzivnosti), se je pri zelo majhnem številu bolnikov, ki so jemali zdravilo CellCept, pojavil rak limfatičnih tkiv in kože.
English: When comparing rates of transplant rejection, rates of graft loss or adverse event profiles between CellCept patients with and without concomitant telmisartan medication, no clinical consequences of the pharmacokinetic drug-drug interaction were seen.
Slovenian: Ko so primerjali deleže zavrnitve presadka, deleže izgube presadka ali profile neželenih učinkov med bolniki, zdravljenimi z zdravilom CellCept v kombinaciji s telmisartanom ali brez njega, niso opazili nobenih kliničnih posledic farmakokinetičnega medsebojnega delovanja med zdraviloma.
English: even if their symptoms are the same as yours
Slovenian: Njim bi lahko celo škodovalo, čeprav imajo znake bolezni, podobne vašim.
English: If you are allergic (hypersensitive) to mycophenolate mofetil, mycophenolic acid or any of the other ingredients in this medicine (listed in Section 6) If you are a woman who could be pregnant and you have not provided a negative pregnancy test before your first prescription, as mycophenolate causes birth defects and miscarriage.
Slovenian: Ne jemljite zdravila CellCept: • če ste alergični (preobčutljivi) na mofetilmikofenolat, mikofenolno kislino ali katero koli sestavino tega zdravila (navedeno v poglavju 6), • če ste bolnica, ki bi lahko bila noseča, in pred prvim predpisanim receptom nimate potrjenega negativnega testa nosečnosti, saj lahko mofetilmikofenolat povzroči prirojene okvare in spontani splav,
English: If you need to have a vaccine (a live vaccine) while taking CellCept, talk to your doctor or pharmacist first.
Slovenian: Če se morate cepiti (z živim cepivom), medtem ko jemljete zdravilo CellCept, se prej pogovorite z zdravnikom ali farmacevtom.
English: In addition, a pregnancy follow-up questionnaire including details of exposure during pregnancy, including timing and dose; duration of therapy, before and during pregnancy; concomitant drugs; known teratogenic risks and full details of congenital malformations should be agreed to with the national competent authorities.
Slovenian: Dodatno se je treba z nacionalnim organom, pristojnim za zdravila, dogovoriti o vprašalniku o spremljanju nosečnosti, ki bo vseboval podrobnosti o izpostavitvi med nosečnostjo, času in odmerku, trajanju zdravljenja pred in med nosečnostjo, sočasno uporabljenih zdravilih, znanih tveganjih za teratogenost in vsemi podrobnostmi o kongenitalnih malformacijah.
English: CellCept 500 mg powder for concentrate for solution for infusion must be prepared in two steps: the first step is a reconstitution step with glucose intravenous infusion 5% and the second step is a dilution step with glucose intravenous infusion 5%.
Slovenian: Zdravilo CellCept 500 mg prašek za koncentrat za raztopino za infundiranje moramo pripraviti v dveh korakih: prvi korak je rekonstitucija z intravensko infuzijo 5-% glukoze, drugi korak pa je razredčitev z intravensko infuzijo 5-% glukoze.
English: This data support extrapolation of this finding to all antacids because the reduction in exposure when CellCept was coadministered with magnesium and aluminium hydroxides is considerably less than when CellCept was co-administered with PPIs.
Slovenian: Ti podatki podpirajo ekstrapolacijo teh ugotovitev na vse antacide, saj je zmanjšanje izpostavljenosti, kadar je zdravilo CellCept sočasno uporabljeno z magnezijevimi in aluminijevi hidroksidi, občutno manjše v primerjavi s sočasno uporabo zdravila CellCept in zaviralcev protonske črpalke.
English: It is recommended that the suspension be reconstituted by the pharmacist prior to dispensing to the patient
Slovenian: Priporočljivo je, da suspenzijo pred izdajo zdravila bolniku pripravi farmacevt Pred uporabo preberite priloženo navodilo
English: Add the remainder of water and shake the closed bottle well for about 1 minute.
Slovenian: Dodajte preostalo količino vode in temeljito stresajte zaprto steklenico približno 1 minuto.
English: Agranulocytosis and neutropenia have been reported; therefore, regular monitoring of patients taking CellCept is advised (see section 4.4).
Slovenian: Poročali so tudi o agranulocitozi in nevtropeniji, zato je priporočljivo bolnike, ki prejemajo zdravilo CellCept, redno spremljati (glejte poglavje 4.4).
English: Hypersensitivity reactions to CellCept have been observed (see section 4.8).
Slovenian: Opazili so preobčutljivostne reakcije na zdravilo CellCept (glejte poglavje 4.8).
English: CsA interferes with MPA enterohepatic recycling, resulting in reduced MPA exposures by 30-50% in renal transplant patients treated with CellCept and CsA compared with patients receiving sirolimus or belatacept and similar doses of CellCept (see also section 4.4).
Slovenian: Ciklosporin A vpliva na enterohepatični obtok mikofenolne kisline in s tem zmanjša izpostavljenost mikofenolni kislini za 30-50 % pri bolnikih z ledvičnim presadkom, ki so bili zdravljeni z zdravilom CellCept in ciklosporinom A, v primerjavi z bolniki, ki so prejemali sirolimus ali belatacept in podobne odmerke zdravila CellCept (glejte tudi poglavje 4.4).
English: These include serious allergic reactions (such as anaphylaxis, angioeodema), fever, feeling very tired, difficulty sleeping, pains (such as stomach, chest, joint or muscle), headache, flu symptoms and swelling.
Slovenian: Ti vključujejo resne alergijske reakcije (kot sta anafilaksa, angioedem), povišano telesno temperaturo, utrujenost, motnje spanca, bolečine (bolečino v želodcu, bolečino v prsih, bolečino v sklepih ali mišicah), glavobol, gripi podobne simptome in otekline.
English: What CellCept is and what it is used for What you need to know before you take CellCept How to take CellCept
Slovenian: Kaj je zdravilo CellCept in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo CellCept Kako jemati zdravilo CellCept Možni neželeni učinki
English: Muscular weakness
Slovenian: mišična šibkost
English: If neutropenia develops (absolute neutrophil count < 1.3 x 103/µl), it may be appropriate to interrupt or discontinue CellCept.
Slovenian: Če se pojavi nevtropenija (absolutno število nevtrofilcev < 1,3 x 103/μl), moramo zdravljenje z zdravilom CellCept prekiniti ali opustiti.
English: Do this by: wearing protective clothing which also covers your head, neck, arms and legs using a sunscreen with a high protection factor.
Slovenian: • uporabljate zaščitna oblačila, ki pokrijejo tudi vašo glavo, vrat, roke in noge,
English: Patients on CellCept who develop recurrent infections should have their serum immunoglobulins measured.
Slovenian: Bolnikom, ki jemljejo zdravilo CellCept in se jim okužbe ponavljajo, je treba določiti raven imunoglobulinov v serumu.
English: Adverse reactions attributable to peripheral venous infusion were phlebitis and thrombosis, both observed at 4% in patients treated with CellCept 500 mg powder for concentrate for solution for infusion.
Slovenian: Neželena učinka, ki ju lahko pripišemo periferni venski infuziji, sta bila flebitis in tromboza, ki so ju opazili pri 4 % bolnikov, zdravljenih z zdravilom CellCept 500 mg prašek za koncentrat za raztopino za infundiranje.
English: METHOD AND ROUTE(S) OF ADMINISTRATION For intravenous infusion only Reconstitute and dilute before use Read the package leaflet before use
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA Samo za intravensko infuzijo Pred uporabo rekonstituirajte in razredčite Pred uporabo preberite priloženo navodilo
English: Some of the more usual problems are diarrhoea, fewer white cells or red cells in your blood, infection and vomiting.
Slovenian: Običajne težave Pogostejše težave so driska, zmanjšano število belih ali rdečih krvničk v krvi, okužbe in bruhanje.
English: Take off the child safety bottle cap and push the bottle adapter into the neck of the bottle.
Slovenian: Odstranite za otroke varno zaporko in v vrat steklenice potisnite nastavek za steklenico.
English: The first dose is given to you as soon as possible after the transplant operation.
Slovenian: • Prvi odmerek boste prejeli čimprej po presaditvenem posegu.
English: These are insufficient to make dosage recommendations, and therefore use in this age group is not recommended.
Slovenian: Ti so nezadostni za navodila o priporočenem odmerjanju, zato uporaba zdravila CellCept v tej starostni skupini ni priporočljiva.
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER
Slovenian: Ime in naslov proizvajalca, odgovornega za sproščanje serij
English: Because mycophenolate mofetil has demonstrated teratogenic effects in rats and rabbits, CellCept tablets should not be crushed.
Slovenian: Ker ima mofetilmikofenolat dokazane teratogene učinke pri podganah in kuncih, se CellCept tablet ne ne sme zdrobiti.
English: Musculoskeletal pain such as myalgia, and neck and back pain were also very commonly reported.
Slovenian: Zelo pogosto so poročali tudi o mišično-skeletnih bolečinah, kot so mialgija ter bolečine v vratu in hrbtu.
English: Cytopenias, including leucopenia, anemia, thrombocytopenia and pancytopenia, are known risks associated with mycophenolate mofetil and may lead or contribute to the occurrence of infections and hemorrhages (see section 4.4).
Slovenian: Citopenije, vključno z levkopenijo, anemijo, trombocitopenijo in pancitopenijo, so znana tveganja, povezana z mofetilmikofenolatom, in lahko povzročijo ali prispevajo k nastanku okužb in krvavitev (glejte poglavje 4.4).
English: Renal transplant n = 991
Slovenian: Presaditev ledvice n = 991
English: Dose adjustment of CellCept does not appear to be necessary.
Slovenian: Prilagajanje odmerkov zdravila CellCept ni potrebno.
English: • Take 4 capsules in the morning and then 4 capsules in the evening.
Slovenian: • Vzemite 4 kapsule zjutraj in 4 kapsule zvečer.
English: Take care not to let the made-up medicine get into your eyes.
Slovenian: Bodite previdni, da pripravljeno zdravilo ne pride v oči.
English: There are no data on CellCept with phosphate binders other than sevelamer.
Slovenian: Ni podatkov o dajanju zdravila CellCept z drugimi vezalci fosfatov, razen sevelamerjem.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu/
Slovenian: DATUM ZADNJE REVIZIJE BESEDILA Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila http://www.ema.europa.eu.
English: Oral CellCept should be initiated within 5 days following transplantation.
Slovenian: Peroralno dajanje zdravila CellCept je treba uvesti v 5 dneh po presaditvi.
English: No substantial alteration of MPA pharmacokinetics is anticipated and CellCept dose adjustment is not required.
Slovenian: Znatnih sprememb v farmakokinetiki mikofenolne kisline ni pričakovati, zato prilagajanje odmerkov zdravila CellCept ni potrebno.
English: Hypersensitivity reactions, including angioneurotic oedema and anaphylactic reaction have been reported.
Slovenian: Preobčutljivost Poročali so o preobčutljivostnih reakcijah, vključno z angionevrotskim edemom in anafilaktično reakcijo.
English: Safety and efficacy of CellCept for infusion in paediatric patients have not been established.
Slovenian: Varnost in učinkovitost infuzije zdravila CellCept pri otrocih niso raziskovali.
English: For instruction on reconstitution of the medicinal product before administration, see section 6.6.
Slovenian: Za navodila o rekonstituciji zdravila pred njegovo uporabo glejte poglavje 6.6.
English: The parent substance mycophenolate mofetil can be measured systemically during intravenous infusion.
Slovenian: Prvotno učinkovino mofetilmikofenolat lahko sistematično merimo med intravenskim infundiranjem.
English: • Your womb (uterus) has been removed by surgery (hysterectomy)
Slovenian: • so vam z operacijo odstranili maternico (uterus) - histerektomija;
English: OTHER SPECIAL WARNING(S), IF NECESSARY Do not breathe the powder before constitution or allow it to touch your skin Avoid skin contact with the reconstituted suspension
Slovenian: DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA Praška pred pripravo suspenzije ne vdihavajte Izogibajte se stiku praška s kožo Izogibajte se neposrednemu stiku pripravljene suspenzije s kožo
English: Manufacturing Authorisation holder responsible for batch release: Roche Pharma AG, Emil-Barell-Str. 1, 79639 Grenzach Wyhlen, Germany.
Slovenian: Proizvajalec, odgovoren za sproščanje serije Roche Pharma AG, Emil-Barell-Str. 1, 79639 Grenzach-Wyhlen, Nemčija
English: • Based on literature reports, malformations occurred in 23 to 27% of live births in women exposed to mycophenolate mofetil during pregnancy (compared to 2 to 3 % of live births in the overall population and approximately 4 to 5% of live births in solid organ transplant recipients treated with immunosuppressants other than mycophenolate mofetil).
Slovenian: • V literaturnih poročilih so se malformacije pojavljale pri 23 do 27 % živorojenih otrok bolnic, ki so bile med nosečnostjo izpostavljene mofetilmikofenolatu, (v primerjavi z 2 do 3 % pri živorojenih otrocih v celokupni populaciji ter približno 4 do 5 % pri živorojenih otrocih bolnic s presajenim solidnim organom, zdravljenih z drugimi imunosupresivi razen mofetilmikofenolata).
English: If the infusion solution is not prepared immediately prior to administration, the commencement of administration of the infusion solution should be within 3 hours from reconstitution and dilution of the medicinal product.
Slovenian: Če raztopine za infundiranje ne pripravite takoj pred dajanjem, mora biti začetek dajanja infuzije v 3 urah po rekonstituciji in razredčitvi zdravila.
English: Heart and blood vessel problems such as: change in blood pressure, accelerated heartbeat, widening of blood vessels.
Slovenian: Težave s srcem in krvnimi žilami, kot so: • spremembe krvnega tlaka, pospešen srčni utrip, razširitev krvnih žil.
English: • CellCept tablets are lavender coloured and caplet shaped.
Slovenian: • CellCept tablete so svetlo vijoličaste barve in ovalne oblike.
English: They have “CellCept 250” printed in black on the capsule cap and “Roche” printed in black on the capsule body.
Slovenian: Natisnjen imajo črni napis “CellCept 250” na glavi kapsule in “Roche” na telesu kapsule.
English: Oral CellCept should be initiated within 72 hours following transplantation.
Slovenian: Peroralno dajanje zdravila CellCept je treba uvesti v 72 urah po presaditvi.
English: Male patients of reproductive potential should be made aware of and discuss with a qualified health-care professional the potential risks of fathering a child.
Slovenian: Bolniki, ki lahko spočnejo otroka, se morajo zavedati možnih tveganj spočetja med zdravljenjem in se o njih pogovoriti z usposobljenim zdravstvenim delavcem.
English: Capsules, hard.
Slovenian: trda kapsula
English: CellCept IV solution should never be administered by rapid or bolus intravenous injection.
Slovenian: Intravenske raztopine zdravila CellCept nikoli ne smemo dati kot hitro ali bolusno intravensko injekcijo.
English: The risk/benefit ratio of mycophenolate mofetil in combination with sirolimus has not been established (see also section 4.5).
Slovenian: Razmerja med tveganjem in koristnostjo mofetilmikofenolata v kombinaciji s sirolimusom niso raziskali (glejte tudi poglavje 4.5).
English: Based on the results of a single dose administration study of recommended doses of oral mycophenolate and IV ganciclovir and the known effects of renal impairment on the pharmacokinetics of CellCept (see section 4.2) and ganciclovir, it is anticipated that co-administration of these agents (which compete for mechanisms of renal tubular secretion) will result in increases in MPAG and ganciclovir concentration.
Slovenian: Na podlagi rezultatov študije enkratnega odmerjanja priporočenih odmerkov peroralne oblike mofetilmikofenolata in intravenske oblike ganciklovirja in znanih učinkov ledvične okvare na farmakokinetiko zdravila CellCept (glejte poglavje 4.2) in ganciklovirja, je pričakovati, da bo sočasno dajanje obeh učinkovin, ki tekmujeta v mehanizmih renalne tubularne sekrecije, povzročilo povečanje koncentracij mikofenolglukuronida in ganciklovirja.