FrancophonIA/ELRC3.0 huggingface dataset:
English: If pain persists for more than 12 hours after medical examination, the doctor should be contacted again.
Croatian: Ako bol potraje više od 12 sati nakon liječničkog pregleda, ponovo potražite pomoć liječnika.
English: If someone is accidentally injected with this product, they must seek medical attention immediately even if only a very small amount is injected.
Croatian: Ako se netko nehotično injicira ovim veterinarsko-medicinskim proizvodom, treba potražiti hitnu medicinsku pomoć čak i ako je injicirana vrlo mala količina.
English: Ibraxion may cause a slight rise in body temperature (less than 1°C) for less than 48 hours after injection.
Croatian: Ibraxion može uzrokovati neznatno povišenje tjelesne temperature (za manje od 1°C) u razdoblju kraćem od 48 sati nakon davanja injekcije.
English: The virus in the vaccine has also been modified to allow vaccinated animals to be distinguished from naturally infected animals so allowing better disease management.
Croatian: Virus u cjepivu također je izmijenjen kako bi se omogućilo razlikovanje cijepljenih i prirodno zaraženih životinja, što omogućuje bolju kontrolu bolesti.
English: Protection starts 2 weeks after vaccination and lasts for 6 months.
Croatian: Zaštita započinje dva tjedna nakon cijepljenja i traje 6 mjeseci.
English: The package leaflet should be shown to the doctor.
Croatian: Uputu o VMP-u treba pokazati liječniku.
English: The name of the medicine was changed to Bovalto Ibraxion on 10 August 2016.
Croatian: Naziv lijeka promijenjen je u Bovalto Ibraxion 10. kolovoza 2016.
English: The full EPAR for Bovalto Ibraxion can be found on the Agency's website: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
Croatian: Cjeloviti EPAR za VMP Bovalto Ibraxion nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
English: Bovine rhinotracheitis vaccine (inactivated)
Croatian: Cjepivo protiv rinotraheitisa goveda (inaktivirano)
English: Accidental injection may cause severe pain and swelling, particularly if injected into a joint or finger -this could result in the loss of a finger if prompt medical attention is not given.
Croatian: Nehotična injekcija može prouzročiti jaku bol i oticanje, naročito ako se injicira u zglob prsta, a u rijetkim slučajevima može rezultirati gubitkom zahvaćenog prsta ako nije pružena hitna medicinska pomoć.
English: Two injections are given 3 weeks apart to calves from age 2 weeks provided they have not acquired antibodies against IBR virus from the mother.
Croatian: Daju se dvije injekcije teladi od 2 tjedna starosti u razmaku od 3 tjedna, pod uvjetom da na telad nisu prenijeta antitijela protiv virusa ZRG-a od majke.
English: The withdrawal period for meat and milk from cattle treated with Bovalto Ibraxion is ‘zero' days, which means there is no mandatory waiting time.
Croatian: Razdoblje karencije za meso i mlijeko stoke liječene VMP-om Bovalto Ibraxion iznosi „nula” dana, drugim riječima, nema obveznog perioda čekanja.
English: The injection of Bovalto Ibraxion may cause a temporary tissue reaction at the site of injection, which may last for three weeks and rarely up to five weeks.
Croatian: Injiciranje VMP-a Bovalto Ibraxion može uzrokovati privremenu reakciju tkiva na mjestu injekcije koja može trajati tri tjedna i, u rijetkim slučajevima, do pet tjedana.
English: When there are antibodies the vaccine should be given to calves from age 3 months.
Croatian: Ako postoje antitijela, cjepivo se daje teladi od 3 mjeseca starosti.
English: This summary was last updated in August 2016.
Croatian: Sažetak je posljednji put ažuriran u 08-2016.
English: A booster injection is given at 6 month intervals.
Croatian: Injekcija za docjepljivanje daje se u razmacima od 6 mjeseci.
English: Bovalto Ibraxion is an emulsion containing mineral oil.
Croatian: Bovalto Ibraxion je emulzija koja sadrži mineralno ulje.
English: Field studies were conducted in around 300 cattle of various ages in both an IBR contaminated and an IBR free environment.
Croatian: Terenska ispitivanja provedena su na oko 300 goveda razne dobi, u okružju kontaminiranom ZRG-om i u okružju koje nije bilo kontaminirano ZRG-om.
English: The Agency's Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Bovalto Ibraxion's benefits are greater than its risks and recommended that it be approved for use in the EU.
Croatian: Odbor za veterinarsko-medicinske proizvode (CVMP) pri Agenciji odlučio je da koristi od veterinarsko-medicinskog proizvoda Bovalto Ibraxion nadmašuju s njim povezane rizike te je preporučio njegovo odobrenje za korištenje u Europskoj uniji.
English: It is not intended to provide practical advice on how to use Bovalto Ibraxion.
Croatian: Svrha sažetka nije davati praktične savjete o korištenju VMP-a Bovalto Ibraxion.
English: Cattle vaccinated with Bovalto Ibraxion had protective levels of antibodies to IBR virus at 2 weeks after vaccination and the duration of protection was shown to last 6 months.
Croatian: Stoka cijepljena VMP-om Bovalto Ibraxion imala je zaštitne razine antitijela protiv virusa ZRG-a 2 tjedna nakon cijepljenja i pokazalo se da zaštita traje 6 mjeseci.
English: The European Commission granted a marketing authorisation valid throughout the EU for Bovalto Ibraxion on 9 March 2000.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje je za VMP Bovalto Ibraxion na snazi u Europskoj uniji od 9. ožujka 2000.
English: When Bovalto Ibraxion is given to cattle the animals' immune system recognises the inactive virus as ‘foreign' and makes antibodies against it.
Croatian: Kada se govedo cijepi cjepivom Bovalto Ibraxion, imunosni sustav životinje prepoznaje inaktivni virus kao „strano tijelo” i proizvodi antitijela protiv njega.
English: Bovalto Ibraxion is a veterinary vaccine used to protect cattle against infectious bovine rhinotracheitis (IBR) virus.
Croatian: Bovalto Ibraxion veterinarsko je cjepivo koje se primjenjuje radi zaštite stoke od virusa zaraznog rinotraheitisa goveda (ZRG).
English: IBR virus infections affect the airways with nasal discharge, conjunctivitis (inflammation of the eye) and coughing.
Croatian: Infekcije virusom ZRG-a zahvaćaju dišne putove uzrokujući iscjedak iz nosa, konjunktivitis (upalu oka) i kašalj.
English: Bovalto Ibraxion is available as an emulsion and can only be obtained with a prescription.
Croatian: Bovalto Ibraxion dostupan je kao emulzija i izdaje se samo na recept.
English: This is a summary of the European public assessment report (EPAR) for Bovalto Ibraxion.
Croatian: Ovo je sažetak europskoga javnog izvješća o ocjeni dokumentacije (EPAR) o veterinarsko-medicinskom proizvodu Bovalto Ibraxion.
English: Bovalto Ibraxion contains the adjuvant light paraffin oil to enhance the immune response.
Croatian: Bovalto Ibraxion sadrži lagano parafinsko ulje kao adjuvans kako bi se pojačala imunosna reakcija.
English: Why is Bovalto Ibraxion approved?
Croatian: Zašto je Bovalto Ibraxion odobren?
English: For practical information about using Bovalto Ibraxion, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Praktične informacije o primjeni VMP-a Bovalto Ibraxion vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svojem veterinaru ili ljekarniku.
English: Bovalto Ibraxion is a vaccine containing a version of the IBR virus that has been made inactive so it cannot cause infection.
Croatian: Bovalto Ibraxion cjepivo je koje sadrži inačicu virusa ZRG-a koji je inaktiviran kako ne bi mogao uzrokovati infekciju.
English: For more information about treatment with Bovalto Ibraxion, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Dodatne informacije o terapiji VMP-om Bovalto Ibraxion vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svojem veterinaru ili ljekarniku.
English: What are the risks associated with Bovalto Ibraxion?
Croatian: Koji su rizici povezani s VMP-om Bovalto Ibraxion?
English: Bovalto Ibraxion contains the active substance inactivated gene deleted IBR virus.
Croatian: Bovalto Ibraxion sadrži gE deletirani inaktivirani virus ZRG-a kao djelatnu tvar.
English: Other information about Bovalto Ibraxion?
Croatian: Ostale informacije o VMP-u Bovalto Ibraxion
English: What benefits of Bovalto Ibraxion have been shown in studies?
Croatian: Koje su koristi VMP-a Bovalto Ibraxion dokazane u ispitivanjima?
English: How is Bovalto Ibraxion used?
Croatian: Kako se Bovalto Ibraxion koristi?
English: How does Bovalto Ibraxion work?
Croatian: Kako djeluje Bovalto Ibraxion?
English: What is Bovalto Ibraxion and what is it used for?
Croatian: Što je Bovalto Ibraxion i za što se koristi?
English: MA (EU) number (Invented) name
Croatian: Broj (EU) odobrenja (Zaštićen o) ime
English: Safety features will be implemented until 9/2/2019.
Croatian: Sigurnosne oznake će se implementirati do 9. 2. 2019.
English: Also, it can pass into the breast milk and can reach your baby.
Croatian: Također, može proći u majčino mlijeko i doći do Vaše bebe.
English: Oprymea with food, drink and alcohol
Croatian: Oprymea s hranom, pićem i alkoholom
English: The doctor will advise you on the right dosing.
Croatian: Liječnik će Vas posavjetovati o ispravnom doziranju.
English: Maintenance of efficacy was shown in patients treated for 33 weeks.
Croatian: Održavanje učinka pokazano je na bolesnicima liječenima 33 tjedna.
English: The three strips are marked with "Week 1", "Week 2" and "Week 3".
Croatian: Tri trake su označene sa "1. tjedan", "2. tjedan" i "3. tjedan".
English: Out of these 87 patients, 82.8% did not change their dose, 13.8% increased and 3.4% decreased their dose.
Croatian: Od ovih 87 bolesnika, 82,8% nije promijenilo dozu, 13,8% je povisilo, a 3,4% snizilo svoju dozu.
English: Inform your doctor if you find tablet pieces in your faeces.
Croatian: Obavijestite svog liječnika ako pronađete komadiće tablete u svojoj stolici.
English: A decreased body weight by 30 kg results in an increase in Cmax of 45%.
Croatian: Smanjena tjelesna težina za 30 kg rezultira porastom Cmax od 45%.
English: The increase in Cmax is not considered clinically relevant.
Croatian: Porast u Cmax se ne smatra klinički značajnim.
English: Total exposure (AUC) was not affected by concomitant food intake.
Croatian: Ukupna ekspozicija (AUC) nije bila pogođena istodobnim unosom hrane.
English: Once daily.
Croatian: Primjena jednom dnevno.
English: - Strong impulse to gamble excessively despite serious personal or family consequences.
Croatian: snažan nagon za pretjeranim kockanjem usprkos teškim posljedicama za osobu ili obitelj *
English: What Oprymea is and what it is used for
Croatian: Što je Oprymea i za što se koristi
English: Augmentation was specifically investigated in a controlled clinical trial over 26 weeks.
Croatian: Augmentacija je osobito ispitivana u kontroliranom kliničkom ispitivanju tijekom više od 26 tjedana.
English: Caution should be exercised and careful assessment of therapeutic response and tolerability should be made before increasing to daily dosing after one week.
Croatian: Potreban je oprez, a pažljiva ocjena terapijskog odgovora i podnošljivosti treba se učiniti prije povišenja na dnevno doziranje nakon jednog tjedna.
English: Frequency cannot be estimated from the available data
Croatian: učestalost se ne može procijeniti iz dostupnih podataka
English: <Not applicable.>
Croatian: <Nije primjenjivo.>
English: With 95 % certainty, the frequency category is not greater than uncommon, but might be lower.
Croatian: Sa sigurnošću od 95%, kategorija učestalosti nije veća od "manje često", ali može biti niža.
English: The absolute bioavailability is greater than 90% and the maximum plasma concentrations occur between 1 and 3 hours.
Croatian: Apsolutna bioraspoloživost je veća od 90%, a maksimalne koncentracije u plazmi postižu se za 1-3 sata.
English: However, your dose may have to be increased even further.
Croatian: Međutim, Vaša doza se može čak i dalje povisivati.
English: If you do, there is a danger you could overdose, because the medicine may be released into your body too quickly.
Croatian: Ako to učinite, postoji rizik od predoziranja jer može doći do prebrzog oslobađanja lijeka u tijelo.
English: If you take more Oprymea than you should
Croatian: Ako uzmete više lijeka Oprymea nego što ste trebali
English: Oprymea should not be used during pregnancy unless clearly necessary, i.e. if the potential benefit justifies the potential risk to the foetus.
Croatian: Oprymea se ne smije primjenjivati tijekom trudnoće osim ako nije nužno potrebna, tj. ako očekivana korist opravdava potencijalni rizik za fetus.
English: - Binge eating (eating large amounts of food in a short time period) or compulsive eating
Croatian: prejedanje (jedenje ogromnih količina hrane u kratkom razdoblju) ili kompulzivno jedenje
English: Steady state of exposure is reached at the latest after 5 days of continuous dosing.
Croatian: Stanje dinamičke ravnoteže izloženosti se postiže najkasnije nakon 5 dana neprekidnog doziranja.
English: Augmentation refers to the earlier onset of symptoms in the evening (or even the afternoon), increase in symptoms, and spread of symptoms to involve other extremities.
Croatian: Augmentacija se odnosi na raniji nastup večernjih simptoma (ili čak poslijepodne), povećanje simptoma i širenje simptoma na druge ekstremitete.
English: Other medicines and Oprymea
Croatian: Drugi lijekovi i Oprymea
English: Oprymea can reduce the production of breast milk.
Croatian: Oprymea može smanjiti stvaranje majčinog mlijeka.
English: Such effect was not observed in patient studies.
Croatian: Takav učinak nije primijećen u ispitivanjima na bolesnicima.
English: If during treatment your kidney problems get worse, you should contact your doctor as soon as possible.
Croatian: Ako se tijekom liječenja Vaši problemi s bubrezima pogoršaju, potrebno je javiti se liječniku čim je prije moguće.
English: Remnants in stool
Croatian: Ostaci u stolici
English: The effect on pregnancy and lactation has not been investigated in humans.
Croatian: Učinak na trudnoću i dojenje nije istraživan u ljudi.
English: - Augmentation.
Croatian: Augmentacija.
English: Stimulation of the dopamine receptors triggers nerve impulses in the brain that help to control body movements.
Croatian: Stimulacija dopaminskih receptora pokreće živčane impulse u mozgu koji pomažu u kontroli pokreta tijela.
English: In open continuation trials lasting for more than three years there were no signs of decreasing efficacy.
Croatian: Također u otvorenim produženim studijama u trajanju preko 3 godine nije bilo znakova smanjenja djelotvornosti.
English: Swallow the tablets whole with water.
Croatian: Progutajte tabletu cijelu s vodom.
English: Always take this medicine exactly as your doctor or pharmacist has told you.
Croatian: Uvijek uzmite ovaj lijek točno onako kako je opisano u ovoj uputi ili kako Vam je rekao liječnik ili ljekarnik.
English: The frequency category is probably not greater than "uncommon".
Croatian: Kategorija učestalosti vjerojatno nije veća od „manje često“.
English: This includes medicines, herbal remedies, health foods or supplements that you have obtained without a prescription.
Croatian: To uključuje i lijekove, biljne pripravke, zdravu hranu ili dodatke prehrani koje ste nabavili bez recepta.
English: It can be used alone or in combination with levodopa (another medicine for Parkinson's disease).
Croatian: Može se primjenjivati sam ili u kombinaciji s levodopom (drugi lijek protiv Parkinsonove bolesti).
English: The elimination half-life (t½) varies from 8 hours in the young to 12 hours in the elderly.
Croatian: Poluvrijeme eliminacije (t½) varira od 8 sati u mladih sve do 12 sati u starijih osoba.
English: Do not take Oprymea: - if you are allergic to pramipexole or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte uzimati lijek Oprymea: ako ste alergični na pramipeksol ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: - Altered or increased sexual interest and behaviour of significant concern to you or to others, for example, an increased sexual drive.
Croatian: promijenjeno ili povećano zanimanje za seks i ponašanje koje zabrinjava Vas ili druge, na primjer, povećani spolni nagon
English: Simply leave out that dose completely and then take your next dose at the right time.
Croatian: Jednostavno u potpunosti izostavite tu dozu, a zatim uzmite sljedeću dozu u točno vrijeme.
English: Kaplan-Meier analysis of time to augmentation showed no significant difference between pramipexole and placebo groups.
Croatian: Kaplan-Meierova analiza vremena do pojave augmentacije nije pokazala značajnu razliku između skupina na pramipeksolu i placebu.
English: Pharmacotherapeutic group: anti-Parkinson drugs, dopamine agonists, ATC code: N04BC05.
Croatian: Farmakoterapijska skupina: antiparkinsonici, agonisti dopamina, ATK oznaka: N04BC05.
English: Date of first authorisation: 12 September 2008 Date of latest renewal: 9 April 2013
Croatian: Datum prvog odobrenja: 12. rujna 2008.
English: If renal function declines during maintenance therapy, the recommendations given above should be followed.
Croatian: Ako se bubrežna funkcija smanji tijekom terapije održavanja, potrebno je slijediti gore navedene preporuke.
English: A total of 63 patients were randomised (43 on pramipexole, 20 on placebo).
Croatian: Ukupno je 63 bolesnika bilo randomizirano (43 je bilo na pramipeksolu, 20 na placebu).
English: While body weight has no impact on the AUC, it was found to influence the volume of distribution and therefore the peak concentrations Cmax.
Croatian: Dok tjelesna težina nema utjecaj na AUC, pronađeno je da ima utjecaj na volumen distribucije i stoga vršne koncentracije u plazmi Cmax.
English: If patients report such an observation, the physician should reassess patient's response to therapy.
Croatian: Ako bolesnici prijave takvo opažanje, liječnik treba ponovno procijeniti bolesnikov odgovor na terapiju.
English: The daily dose you take of Oprymea increases each week.
Croatian: Dnevna doza lijeka Oprymea kojeg uzimate povećava se svaki tjedan.
English: The effect of Oprymea on the unborn child is not known.
Croatian: Učinak lijeka Oprymea na nerođeno dijete nije poznat.
English: Clinical efficacy and safety in Parkinson's disease
Croatian: Klinička djelotvornost i sigurnost u Parkinsonovoj bolesti
English: Efficacy was maintained in 87 of 103 patients switched to pramipexole prolonged-release tablets.
Croatian: Učinkovitost je održana u 87 od 103 bolesnika koji su prešli na pramipeksol tablete s produljenim oslobađanjem.
English: Then take your Oprymea prolonged-release tablets next morning and do not take any more Oprymea (immediate release) tablets.
Croatian: Zatim uzmite Oprymea tablete s produljenim oslobađanjem sljedeće jutro i nemojte više uzimati Oprymea tablete (s trenutnim oslobađanjem).
English: Take care if you are using any medicines that calm you down (have a sedative effect) or if you are drinking alcohol.
Croatian: Budite oprezni ako primjenjujete bilo koje lijekove za smirenje (imaju sedativni učinak) ili ako konzumirate alkohol.
English: Do not take a double dose to make up for a forgotten tablet dose.
Croatian: Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu tabletu.
English: Tell your doctor if you experience any of these behaviours; he will discuss ways of managing or reducing the symptoms.
Croatian: Obavijestite liječnika ako primijetite neko od ovih ponašanja; on će raspraviti o načinima njihova zbrinjavanja ili smanjivanja simptoma.
English: The daily dose is administered in equally divided doses 3 times a day.
Croatian: Dnevna doza se primjenjuje u ravnomjerno podijeljenim dozama 3 puta dnevno.
English: What you need to know before you take Oprymea
Croatian: Što morate znati prije nego počnete uzimati lijek Oprymea
English: Therefore, do not take Oprymea if you are pregnant unless your doctor tells you to do so.
Croatian: Stoga nemojte uzimati lijek Oprymea tijekom trudnoće, osim ako Vam to ne preporuči liječnik.
English: Rare: - Mania (agitation, feeling elated or over-excited)
Croatian: Rijetko: manija (uznemirenost, osjećaj ushita ili pretjeranog uzbuđenja)
English: Augmentation was observed in 11.8% of patients in the pramipexole group (N = 152) and 9.4% of patients in the placebo group (N = 149).
Croatian: Augmentacija je primijećena u 11,8% bolesnika u skupini na pramipeksolu (N=152) i 9,4% bolesnika u skupini na placebu (N=149).
English: Do not use this medicine after the expiry date which is stated on the packaging after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju iza „EXP“.
English: The tablets may be taken either with or without food and should be taken each day at about the same time.
Croatian: Tablete se mogu uzimati s hranom ili bez nje, te se uzimaju svaki dan, otprilike u isto vrijeme.
English: What Oprymea is and what it is used for What you need to know before you take Oprymea How to take Oprymea
Croatian: Što je Oprymea i za što se koristi Što morate znati prije nego počnete uzimati lijek Oprymea
English: The Oprymea treatment initiation pack contains three blister strips of tablets - one strip for each of the first three weeks of your treatment.
Croatian: Oprymea pakiranje za početno liječenje sadrži 3 blister trake tableta - jedna traka za svaki od tri tjedna Vašeg liječenja.
English: You may experience that symptoms start earlier than usual, be more intense and involve other limbs.
Croatian: Do pojave simptoma može doći ranije nego obično, mogu biti intenzivniji, te uključivati druge udove.
English: Out of these, approximately 1,000 were in more advanced stages, received concomitant levodopa therapy, and suffered from motor complications.
Croatian: Njih oko 1000 bili su u uznapredovalim stadijima bolesti, istodobno su dobivali terapiju levodopom, te su imali motoričke komplikacije.
English: Concomitant administration with food does generally not affect the bioavailability of pramipexole.
Croatian: Istodobna primjena s hranom općenito ne utječe na bioraspoloživost pramipeksola.
English: If you forget for more than 12 hours, simply take the next single dose at the usual time.
Croatian: Ako se sjetite nakon više od 12 sati, jednostavno uzmite sljedeću jednostruku dozu u uobičajeno vrijeme.
English: BLISTER/(Alu/Alu)
Croatian: BLISTER/(Al/Al)
English: If you suffer from Restless Legs Syndrome, you may experience the following side effects:
Croatian: Ako patite od sindroma nemirnih nogu, možete imati sljedeće nuspojave:
English: If you suffer from Parkinson's disease, you may experience the following side effects:
Croatian: Ako patite od Parkinsonove bolesti, možete imati sljedeće nuspojave:
English: Nausea and fatigue were more often reported in female patients (20.8% and 10.5%, respectively) compared to males (6.7% and 7.3%, respectively).
Croatian: Mučnina i umor češće su prijavljeni u žena (20,8% i 10,5%, po istom redoslijedu) u usporedbi s muškarcima (6,7% i 7,3%, po istom redoslijedu).
English: 20 tablets 30 tablets 60 tablets 90 tablets 100 tablets
Croatian: 20 tableta 30 tableta 60 tableta 90 tableta 100 tableta
English: The Oprymea treatment initiation pack is only to be used for the beginning of the treatment with Oprymea.
Croatian: Oprymea pakiranje za početno liječenje se koristi samo za početak liječenja lijekom Oprymea.
English: Parts of tablets may occasionally be passed and seen in the stool (faeces) and may look like whole tablets.
Croatian: Dijelovi tablete ponekad mogu proći kroz probavni sustav i vidjeti se u stolici (fecesu), a mogu izgledati i kao čitave tablete.
English: Inhibitors/competitors of active renal elimination pathway Cimetidine reduced the renal clearance of pramipexole by approximately 34%, presumably by inhibition of the cationic secretory transport system of the renal tubules.
Croatian: Inhibitori/kompetitori aktivnog renalnog sustava eliminacije Cimetidin smanjuje klirens pramipeksola u bubrezima za oko 34%, vjerojatno inhibicijom kationskog sekrecijskog transportnog sustava u renalnim tubulima.