FrancophonIA/ELRC3.0 huggingface dataset:
English: Increases in clotting tests (PT, INR, and aPTT) were consistent with the effects of apixaban alone.
Slovenian: Povečanja vrednosti testov strjevanja krvi (PČ, INR in aPTČ) so bila skladna z učinki samostojno uporabljenega apiksabana.
English: The next dose of apixaban may be given at least 5 hours after catheter removal.
Slovenian: Bolnik sme vzeti naslednji odmerek apiksabana najmanj 5 ur po odstranitvi katetra.
English: In patients with severe renal impairment (creatinine clearance 15-29 mL/min) the following recommendations apply (see sections 4.4 and 5.2):
Slovenian: Pri bolnikih s hudo okvaro ledvic (očistek kreatinina 15-29 ml/min) veljajo naslednja priporočila (glejte poglavji 4.4 in 5.2):
English: The use of Eliquis may be associated with an increased risk of occult or overt bleeding from any tissue or organ, which may result in posthaemorrhagic anaemia.
Slovenian: Uporaba zdravila Eliquis je lahko povezana z večjim tveganjem za pojav prikrite ali manifestne krvavitve iz kateregakoli tkiva ali organa.
English: Treatment with Eliquis does not require routine monitoring of exposure.
Slovenian: Pri zdravljenju z apiksabanom izpostavljenosti ni treba rutinsko spremljati.
English: Body weight Low body weight (< 60 kg) may increase haemorrhagic risk (see section 5.2).
Slovenian: Telesna masa Majhna telesna masa (< 60 kg) lahko poveča tveganje za krvavitve (glejte poglavje 5.2).
English: • Hepatic disease associated with coagulopathy and clinically relevant bleeding risk (see section 5.2).
Slovenian: • Bolezen jeter, ki je povezana z motnjami strjevanja krvi in klinično pomembnim tveganjem za krvavitve (glejte poglavje 5.2).
English: Prevention of stroke and systemic embolism in adult patients with NVAF, with one or more risk factors (NVAF)
Slovenian: Preprečevanje možganske kapi in sistemske embolije pri odraslih bolnikih z NVAF in enim ali več dejavniki tveganja (NVAF)
English: Renal impairment had no evident effect on the relationship between apixaban plasma concentration and anti-FXa activity.
Slovenian: Okvara ledvic nima očitnih vplivov na razmerje med koncentracijami apiksabana v plazmi in aktivnostjo anti-FXa.
English: Inducers of CYP3A4 and P-gp
Slovenian: Induktorji CYP3A4 in P-gp
English: Apixaban can be taken with or without food.
Slovenian: Apiksaban se lahko jemlje skupaj s hrano ali brez nje.
English: Major*
Slovenian: Večje*
English: Fertility Studies in animals dosed with apixaban have shown no effect on fertility (see section 5.3).
Slovenian: Pri študijah na živalih, ki so prejemale apiksaban, vpliva na plodnost niso ugotovili (glejte poglavje 5.3).
English: If a blood clot travels from your leg to your lungs, it can block blood flow causing breathlessness, with or without chest pain.
Slovenian: Če krvni strdek iz noge zaide v pljuča, lahko prepreči pretok krvi v pljučih in povzroči težko dihanje, ki ga lahko spremlja bolečina v prsnem košu ali pa tudi ne.
English: The first dose of apixaban was given 12 to 24 hours post-surgery, whereas enoxaparin was started 9 to 15 hours prior to surgery.
Slovenian: Bolniki so prvi odmerek apiksabana prejeli od 12 do 24 ur po operaciji, prvi odmerek enoksaparina pa od 9 do 15 ur pred operacijo.
English: Key Elements of the Prescriber Guide:
Slovenian: Ključni elementi navodila za zdravnike, ki predpisujejo zdravilo:
English: EMANATE, an open-label, multi-center study, enrolled 1500 patients who were either oral anticoagulant naïve or pre-treated less than 48 hours, and scheduled for cardioversion for NVAF.
Slovenian: EMANATE je bila odprta multicentrična študija, v katero so vključili 1.500 bolnikov, naročenih na kardioverzijo zaradi NVAF, ki bodisi predhodno niso prejeli peroralnega antikoagulacijskega zdravljenja bodisi so se predhodno zdravili manj kot 48 ur.
English: Eliquis contains the active substance apixaban and belongs to a group of medicines called anticoagulants.
Slovenian: Učinkovina zdravila Eliquis je apiksaban, ki sodi v skupino zdravil, imenovano antikoagulanti.
English: Eliquis should be discontinued at least 24 hours prior to elective surgery or invasive procedures with a low risk of bleeding.
Slovenian: Z uporabo zdravila Eliquis je treba prenehati najmanj 24 ur pred načrtovano operacijo ali invazivnimi postopki, pri katerih je prisotno majhno tveganje za krvavitve.
English: Reversal of Eliquis pharmacodynamic effects, as demonstrated by changes in the thrombin generation assay, was evident at the end of infusion and reached baseline values within 4 hours after the start of a 4-factor PCC 30 minute infusion in healthy subjects.
Slovenian: Pri zdravih preskušancih so ugotovili izgubo farmakodinamičnih učinkov zdravila Eliquis, dokazano s spremembami vrednosti testov tvorbe trombina ob koncu infundiranja 30 minutne infuzije, pri čemer je bila izhodiščna vrednost dosežena v 4 urah po začetku infundiranja 4-faktorskih pripravkov PCC.
English: Alu-PVC/PVdC blisters.
Slovenian: Pretisni omoti iz Alu-PVC/PVdC.
English: All-cause death occurred in 2 patients (0.27%) in the apixaban group and 1 patient (0.13%) in the heparin and/or VKA group.
Slovenian: Do smrti iz vseh vzrokov je prišlo pri 2 bolnikih (0,27 %) v skupini z apiksabanom in pri 1 bolniku (0,13 %) v skupini s heparinom in/ali AVK.
English: If your abnormal heartbeat needs to be restored to normal by a procedure called cardioversion, take Eliquis at the times your doctor tells you, to prevent blood clots in blood vessels in your brain and other blood vessels in your body.
Slovenian: Če imate nenormalen srčni utrip in za povrnitev na normalnega potrebujete postopek, imenovan kardioverzija, jemljite zdravilo Eliquis takrat, kot vam je to predpisal zdravnik, da preprečite nastanek krvnih strdkov v možganskih žilah in drugih žilah v telesu.
English: • The active substance is apixaban.
Slovenian: • Učinkovina je apiksaban.
English: The signs, symptoms, and severity will vary according to the location and degree or extent of the bleeding (see sections 4.4 and 5.1).
Slovenian: Posledično se lahko razvije posthemoragična anemija, katere znaki, simptomi in resnost so odvisni od mesta in stopnje ali obsega krvavitve (glejte poglavji 4.4 in 5.1).
English: Eliquis should be used with caution when coadministered with SSRIs/SNRIs or NSAIDs (including acetylsalicylic acid) because these medicinal products typically increase the bleeding risk.
Slovenian: Pri sočasni uporabi zdravila Eliquis in SSRI/SNRI ali NSAID (vključno z acetilsalicilno kislino) je potrebna previdnost, saj je za ta zdravila značilno, da povečajo tveganje za krvavitve.
English: If bleeding occurs, surgery, blood transfusions, or other treatments that may reverse anti-factor Xa activity may be required.
Slovenian: V primeru krvavitve bo morda potrebna operacija, transfuzija krvi ali zdravljenje z drugimi zdravili, ki lahko zaustavijo zaviralno delovanje na faktor Xa.
English: * There were no occurrences of generalized pruritus in CV185057 (long term prevention of VTE)
Slovenian: * V študiji CV185057 (dolgotrajno preprečevanje VTE) niso opazili pojava generaliziranega pruritusa.
English: For patients who are unable to swallow whole tablets, Eliquis tablets may be crushed and suspended in water, or 5% dextrose in water (D5W), or apple juice or mixed with apple puree and immediately administered orally (see section 5.2).
Slovenian: Bolnikom, ki niso zmožni pogoltniti celih tablet, lahko tablete zdravila Eliquis zdrobimo in suspendiramo v vodi, 5 % glukozi in vodi (D5W) ali jabolčnem soku, lahko pa jih zmešamo z jabolčno čežano, nato pa morajo pripravljeno nemudoma zaužiti (glejte poglavje 5.2).
English: * Noninferior compared to enoxaparin/warfarin (p-value < 0.0001)
Slovenian: * enakovreden v primerjavi z enoksaparinom/varfarinom (vrednost p < 0,0001)
English: Patients undergoing catheter ablation (NVAF) Patients can continue apixaban use while undergoing catheter ablation (see sections 4.3, 4.4 and 4.5).
Slovenian: Bolniki s katetrsko ablacijo (NVAF) Med katetrsko ablacijo lahko bolniki še naprej uporabljajo apiksaban (glejte poglavja 4.3, 4.4 in 4.5).
English: Included in this total were 1,262 patients (618 in the apixaban group) of age 75 or older, 1,004 patients (499 in the apixaban group) with low body weight (≤ 60 kg), 1,495 patients (743 in the apixaban group) with BMI ≥ 33 kg/m2, and 415 patients (203 in the apixaban group) with moderate renal impairment.
Slovenian: Med vsemi vključenimi bolniki je bilo 1.262 bolnikov (618 v skupini z apiksabanom), ki so bili stari 75 let ali starejši, 1.004 bolniki (499 v skupini z apiksabanom), ki so imeli majhno telesno maso (≤ 60 kg), 1.495 bolnikov (743 v skupini z apiksabanom), ki so imeli indeks telesne mase ≥ 33 kg/m2 in 415 bolnikov (203 v skupini z apiksabanom), ki so imeli zmerno okvaro ledvic.
English: This condition (pulmonary embolism) can be life-threatening and requires immediate medical attention.
Slovenian: To stanje (imenovano tudi pljučna embolija) lahko ogrozi življenje in zahteva takojšnje zdravljenje.
English: Yellow iron oxide (E172)
Slovenian: triacetin rumeni železov oksid (E172)
English: Therefore, apixaban is not expected to alter the metabolic clearance of coadministered medicinal products that are metabolised by these enzymes.
Slovenian: Za apiksaban se torej ne pričakuje, da bi spremenil presnovni očistek sočasno uporabljenih zdravil, ki se presnavljajo preko teh encimov.
English: Therefore, haemodialysis is unlikely to be an effective means of managing apixaban overdose.
Slovenian: Zato hemodializa verjetno ne bo učinkovita pri obravnavanju prevelikega odmerjanja apiksabana.
English: 10 film-coated tablets 20 film-coated tablets 60 film-coated tablets 60 x 1 film-coated tablets 100 x 1 film-coated tablets 168 film-coated tablets 200 film-coated tablets
Slovenian: 10 filmsko obloženih tablet 20 filmsko obloženih tablet 60 filmsko obloženih tablet 60 x 1 filmsko obložena tableta 100 x 1 filmsko obložena tableta 168 filmsko obloženih tablet 200 filmsko obloženih tablet
English: Major bleeding and CRNM bleeding events occurred in 3 (0.41%) and 11 (1.50%) patients, respectively, in the apixaban group, compared to 6 (0.83%) and 13 (1.80%) patients in the heparin and/or VKA group.
Slovenian: Do večjih krvavitev in KPMK je prišlo pri 3 (0,41 %) oziroma 11 (1,50 %) bolnikih v skupini z apiksabanom v primerjavi s 6 (0,83 %) oziroma 13 (1,80 %) bolniki v skupini s heparinom in/ali AVK.
English: - if you have a prosthetic heart valve - if your doctor determines that your blood pressure is unstable or another treatment or surgical procedure to remove the blood clot from your lungs is planned
Slovenian: če imate protetično srčno zaklopko če zdravnik ugotovi, da je vaš krvni tlak nestabilen, ali če za odstranitev krvnega strdka iz pljuč načrtuje drugo obliko zdravljenja ali kirurški poseg
English: 14 film-coated tablets 20 film-coated tablets 28 film-coated tablets 56 film-coated tablets 60 film-coated tablets 100x 1 film-coated tablets 168 film-coated tablets 200 film-coated tablets
Slovenian: 14 filmsko obloženih tablet 20 filmsko obloženih tablet 28 filmsko obloženih tablet 56 filmsko obloženih tablet 60 filmsko obloženih tablet 100 x 1 filmsko obložena tableta 168 filmsko obloženih tablet 200 filmsko obloženih tablet
English: Eliquis should be discontinued at least 48 hours prior to elective surgery or invasive procedures with a moderate or high risk of bleeding.
Slovenian: Z uporabo zdravila Eliquis je treba prenehati najmanj 48 ur pred načrtovano operacijo ali invazivnimi postopki, pri katerih je prisotno zmerno ali veliko tveganje za krvavitve.
English: In studies conducted in healthy subjects, as described below, apixaban did not meaningfully alter the pharmacokinetics of digoxin, naproxen, or atenolol.
Slovenian: V študijah, izvedenih pri zdravih osebah, apiksaban ni pomembneje spremenil farmakokinetike digoksina, naproksena ali atenolola.
English: These medicinal products may increase apixaban exposure by 2-fold (see section 4.5), or greater in the presence of additional factors that increase apixaban exposure (e.g., severe renal impairment).
Slovenian: Ta zdravila lahko izpostavljenost apiksabanu povečajo za 2-krat (glejte poglavje 4.5), v prisotnosti dodatnih dejavnikov, ki povečajo izpostavljenost apiksabanu (npr. huda okvara ledvic), pa tudi za več kot 2-krat.
English: Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa.
Slovenian: Apiksaban je močan, reverzibilen, neposreden in visoko selektiven zaviralec aktivnega mesta faktorja Xa za peroralno uporabo.
English: Changes observed in these clotting tests at the expected therapeutic dose are small and subject to a high degree of variability (see section 5.1).
Slovenian: Pri pričakovanih terapevtskih odmerkih so spremembe vrednosti teh testov strjevanja krvi majhne in zelo spremenljive (glejte poglavje 5.1).
English: Treatment of DVT, treatment of PE and prevention of recurrent DVT and PE (VTEt) The clinical program (AMPLIFY: apixaban versus enoxaparin/warfarin, AMPLIFY-EXT: apixaban versus placebo) was designed to demonstrate the efficacy and safety of apixaban for the treatment of DVT and/or PE (AMPLIFY), and extended therapy for the prevention of recurrent DVT and/or PE following 6 to 12 months of anticoagulant treatment for DVT and/or PE (AMPLIFY-EXT).
Slovenian: Zdravljenje GVT, zdravljenje PE in preprečevanje ponovne GVT ter PE (VTEt) Zasnovan je bil klinični program (AMPLIFY: primerjava apiksabana in enoksaparina/varfarina, AMPLIFY-EXT: primerjava apiksabana in placeba) za dokazovanje učinkovitosti in varnosti apiksabana pri zdravljenju GVT in/ali PE (AMPLIFY) ter pri podaljšanem zdravljenju za preprečevanje ponovitve GVT in/ali PE, ki je sledilo od 6- do 12-mesečnemu antikoagulacijskemu zdravljenju GVT in/ali PE (AMPLIFY-EXT).
English: Prior to initiating Eliquis, liver function testing should be performed.
Slovenian: Pred začetkom uporabe zdravila Eliquis je treba preveriti delovanje jeter.
English: It is unknown whether apixaban or its metabolites are excreted in human milk.
Slovenian: Ni znano, če se apiksaban ali njegovi presnovki izločajo v materino mleko.
English: Post-surgery treatment period Major
Slovenian: Obdobje zdravljenja po operaciji Večje
English: If you take more Eliquis than recommended, you may have an increased risk of bleeding.
Slovenian: Če ste vzeli večji odmerek zdravila Eliquis, kot bi smeli, se lahko poveča tveganje za krvavitve.
English: In this clinical trial, there was limited (2.1%) use of concomitant dual antiplatelet therapy.
Slovenian: V tem kliničnem preskušanju je bil delež sočasne uporabe dveh zaviralcev agregacije trombocitov omejen (2,1 %).
English: Intake with food does not affect apixaban AUC or Cmax at the 10 mg dose.
Slovenian: Hrana ne vpliva na vrednosti AUC ali Cmax 10 mg odmerka.
English: Alternatively, Eliquis tablets may be crushed and suspended in 60 mL of water or D5W and immediately delivered through a nasogastric tube (see section 5.2).
Slovenian: Druga možnost je, da tablete zdravila Eliquis zdrobimo in suspendiramo v 60 ml vode ali D5W in jih bolniku nemudoma damo preko nazogastrične sonde (glejte poglavje 5.2).
English: As with all new anticoagulant medicinal products, experience with neuraxial blockade is limited and extreme caution is therefore recommended when using apixaban in the presence of neuraxial blockade.
Slovenian: Kot pri drugih novih antikoagulantih je izkušenj z nevroaksialno blokado malo, zato je pri sočasni uporabi apiksabana in nevroaksialne blokade potrebna izjemna previdnost.
English: - Take the dose as soon as you remember and: - take the next dose of Eliquis at the usual time - then continue as normal.
Slovenian: Odmerek vzemite takoj, ko se spomnite in: naslednji odmerek zdravila Eliquis nato vzemite ob običajnem času.
English: The initiation of appropriate treatment, e.g., surgical haemostasis, the transfusion of fresh frozen plasma or the administration of a reversal agent for factor Xa inhibitors should be considered.
Slovenian: Razmisliti je treba o uvedbi ustreznega zdravljenja, npr. o kirurški hemostazi, transfuziji sveže zamrznjene plazme ali uporabi protiučinkovine za zaviralce faktorja Xa.
English: If you forget to take Eliquis
Slovenian: Če ste pozabili vzeti zdravilo Eliquis
English: If you take more Eliquis than you should
Slovenian: Če ste vzeli večji odmerek zdravila Eliquis, kot bi smeli
English: Electrical and/or pharmacologic cardioversion was conducted after at least 5 doses of 5 mg twice daily apixaban (or 2.5 mg twice daily in selected patients (see section 4.2)) or at least 2 hours after a 10 mg loading dose (or a 5 mg loading dose in selected patients (see section 4.2)) if earlier cardioversion was required.
Slovenian: Električno in/ali farmakološko kardioverzijo so opravili po vsaj 5 odmerkih apiksabana 5 mg dvakrat na dan (oziroma 2,5 mg dvakrat na dan pri izbranih bolnikih (glejte poglavje 4.2)) ali vsaj 2 uri po 10 mg polnilnem odmerku (oziroma 5 mg polnilnem odmerku pri izbranih bolnikih (glejte poglavje 4.2)), če je bilo treba kardioverzijo opraviti prej.
English: Efficacy and safety of apixaban in the treatment of DVT, treatment of PE and prevention of recurrent DVT and PE (VTEt) in patients with active cancer have not been established.
Slovenian: Varnost in učinkovitost apiksabana pri zdravljenju GVT, zdravljenju PE in preprečevanju ponovne GVT ter PE pri bolnikih z aktivnim rakom nista bili dokazani.
English: This exploratory study showed comparable efficacy and safety between apixaban and heparin and/or VKA treatment groups in the setting of cardioversion.
Slovenian: Ta raziskovalna študija je pokazala primerljivo učinkovitost in varnost pri kardioverziji med skupinama, ki sta se zdravili z apiksabanom oziroma heparinom in/ali AVK.
English: Inhibitors of CYP3A4 and P-gp
Slovenian: Zaviralci CYP3A4 in P-gp
English: For situations when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding, a reversal agent for factor Xa inhibitors is available (see section 4.4).
Slovenian: V situacijah, kadar je treba zaustaviti antikoagulacijo zaradi življenjsko ogrožajoče ali nenadzorovane krvavitve, je na voljo protiučinkovina za zaviralce faktorja Xa (glejte poglavje 4.4).
English: The relationship between apixaban plasma concentration and anti-FXa activity is approximately linear over a wide dose range of apixaban.
Slovenian: Razmerje med koncentracijami apiksabana v plazmi in aktivnostjo anti-FXa je približno linearno v širokem razponu odmerkov apiksabana.
English: Use of thrombolytic agents for the treatment of acute ischemic stroke There is very limited experience with the use of thrombolytic agents for the treatment of acute ischemic stroke in patients administered apixaban.
Slovenian: Uporaba trombolitičnih učinkovin za zdravljenje akutne ishemične možganske kapi Izkušnje z uporabo trombolitičnih učinkovin za zdravljenje akutne ishemične možganske kapi pri bolnikih, ki so prejemali apiksaban, so zelo omejene.
English: Limited clinical data indicate that apixaban plasma concentrations are increased in patients with severe renal impairment (creatinine clearance 15-29 mL/min) which may lead to an increased bleeding risk.
Slovenian: Omejeni klinični podatki kažejo, da se pri bolnikih s hudo okvaro ledvic (očistek kreatinina 1529 ml/min) koncentracije apiksabana v plazmi povečajo, kar lahko poveča tveganje za krvavitve.
English: Treatment of DVT, treatment of PE and prevention of recurrent DVT and PE (VTEt) The recommended dose of apixaban for the treatment of acute DVT and treatment of PE is 10 mg taken orally twice daily for the first 7 days followed by 5 mg taken orally twice daily.
Slovenian: Zdravljenje GVT, zdravljenje PE ter preprečevanje ponovne GVT in PE (VTEt - VTE therapy) Priporočeni odmerek apiksabana za zdravljenje akutne GVT in zdravljenje PE je 10 mg peroralno dvakrat na dan prvih 7 dni, čemur sledi 5 mg peroralno dvakrat na dan.
English: Changes in anti-Factor Xa activity and INR were comparable between subjects with mild to moderate hepatic impairment and healthy subjects.
Slovenian: Spremembe v aktivnosti anti-FXa in INR so bile pri bolnikih z blago do zmerno okvaro jeter primerljive s spremembami pri zdravih osebah.
English: The relationship between apixaban plasma concentration and anti-Factor Xa activity was best described by a linear model.
Slovenian: Razmerje med koncentracijami apiksabana v plazmi in aktivnostjo anti-FXa najbolje opiše linearni model.
English: * Major bleeding defined per International Society on Thrombosis and Haemostasis (ISTH) criteria.
Slovenian: * večja krvavitev, definirana po merilih ISTH (International Society on Thrombosis and Haemostasis) † klinično pomembne manjše krvavitve
English: Eliquis (apixaban) is an oral anticoagulant acting by direct selective inhibition of factor Xa.
Slovenian: Zdravilo Eliquis(apiksaban) je peroralni antikoagulant, ki deluje tako, daneposredno selektivno zavira faktor Xa.
English: Following administration of a crushed 5 mg apixaban tablet suspended in 60 mL of D5W and delivered via a nasogastric tube, exposure was similar to exposure seen in other clinical trials involving healthy subjects receiving a single oral 5 mg apixaban tablet dose.
Slovenian: Po uporabi zdrobljene 5 mg tablete, suspendirane v 60 ml D5W in dane po nazogastrični sondi, je bila izpostavljenost podobna izpostavljenosti, ugotovljeni v drugih kliničnih preskušanjih, ki so vključevala zdrave prostovoljce, ki so prejemali enkratni peroralni 5 mg odmerek apiksabana v obliki tablete.
English: I am under anticoagulation treatment with Eliquis (apixaban) to prevent blood clots
Slovenian: Zdravim se z zdravilom Eliquis (apiksaban), antikoagulantom za preprečevanje nastajanja krvnih strdkov.
English: - for the prevention of stroke and systemic embolism in patients with NVAF, patients should receive the lower dose of apixaban 2.5 mg twice daily.
Slovenian: - pri preprečevanju možganske kapi in sistemske embolije pri bolnikih z NVAF morajo bolniki prejemati manjši odmerek apiksabana, in sicer 2,5 mg dvakrat na dan.
English: Currently there is no experience with the use of recombinant factor VIIa in individuals receiving apixaban.
Slovenian: Trenutno še ni izkušenj z uporabo rekombinantnega faktorja VIIa pri osebah, ki se zdravijo z apiksabanom.
English: Signs and symptoms of bleeding include bruising or bleeding under the skin, tar-coloured stools, blood in urine, nose-bleed, dizziness, tiredness, paleness or weakness, sudden severe headache, coughing up blood or vomiting blood.
Slovenian: Znaki in simptomi krvavitev vključujejo modrice ali krvavitev pod kožo, blato temne barve, kri v urinu, krvavitev iz nosu, omotico, utrujenost, bledico ali šibkost, nenaden in hud glavobol, kri pri izkašljevanju ali kri v bruhanju.
English: Each 2.5 mg film-coated tablet contains 51.43 mg lactose (see section 4.4).
Slovenian: Pomožne snovi z znanim učinkom Ena 2,5 mg filmsko obložena tableta vsebuje 51,43 mg laktoze (glejte poglavje 4.4).
English: ADVANCE-3 (hip)
Slovenian: ADVANCE-3 (kolk)
English: This medicine helps to prevent blood clots from forming by blocking Factor Xa, which is an important component of blood clotting.
Slovenian: Zdravilo zavira aktivnost faktorja Xa, ki je pomembna komponenta strjevanja krvi in tako preprečuje nastanek krvnih strdkov.
English: All the bleeding criteria included surgical site bleeding.
Slovenian: Vsi kriteriji o krvavitvah vključujejo krvavitve iz kirurške rane.
English: If necessary, your doctor may also give you the crushed Eliquis tablet mixed in 60 mL of water or 5% dextrose in water, through a nasogastric tube.
Slovenian: Če je treba, vam lahko zdravnik zdrobljene tablete zdravila Eliquis, zmešane v 60 ml vode ali 5 % glukoze v vodi, da tudi s pomočjo nazogastrične sonde.
English: The most common general side effect of Eliquis is bleeding which may be potentially life threatening and require immediate medical attention.
Slovenian: Najpogostejši splošni neželeni učinek zdravila Eliquis so krvavitve, ki so lahko smrtno nevarne in zahtevajo takojšnje zdravljenje.