FrancophonIA/ELRC3.0 huggingface dataset:
English: EU/1/18/1330/003 (1 pre-filled syringe) EU/1/18/1330/004 (3 pre-filled syringes) EU/1/18/1330/006 (2 pre-filled syringes)
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/18/1330/003 (1 fyldt injektionssprøjte) EU/1/18/1330/004 (3 fyldte injektionssprøjter) EU/1/18/1330/006 (2 fyldte injektionssprøjter)
English: Dispose of the pen in a sharps disposal container or as directed by your doctor, pharmacist or nurse.
Danish: Læg pennen i en kanyleboks, eller bortskaf den som anvist af lægen, apotekspersonalet eller sygeplejersken.
English: • Ask your doctor, pharmacist or nurse about how to dispose of medicines you no longer use.
Danish: • Spørg lægen, apotekspersonalet eller sygeplejersken, hvordan du skal bortskaffe medicinrester.
English: Leave the base cap on until you are ready to inject.
Danish: Lad hætten sidde på, indtil du er klar til at indsprøjte.
English: In patients failing two or more prophylactic treatments, the treatment difference was -2.64 days (p < 0.001) between 120 mg and placebo and -3.04 days (p < 0.001) between 240 mg and placebo.
Danish: Hos patienter, der havde oplevet svigt af mindst to profylaktiske behandlinger, var behandlingsdifferencen -2,64 dage (p < 0,001) mellem 120 mg og placebo og -3,04 dage (p < 0,001) mellem 240 mg og placebo.
English: In pooled data from studies EVOLVE-1 and EVOLVE-2, in patients who failed one or more prophylactic treatments for efficacy reasons, the treatment difference for the reduction of mean monthly MHDs observed between galcanezumab 120 mg and placebo was -2.69 days (p < 0.001) and between galcanezumab 240 mg and placebo -2.78 days (p < 0.001).
Danish: I puljede data fra studierne EVOLVE-1 og EVOLVE-2 var behandlingsdifferencen (fald i gennemsnittet af månedlige MHD'er) hos patienter, der havde oplevet effektsvigt af en eller flere profylaktiske behandlinger, -2,69 dage (p < 0,001) , mellem galcanezumab 120 mg og placebo, og2,78 dage (p < 0,001) mellem galcanezumab 240 mg og placebo.
English: DO NOT put the needle cap back on.
Danish: Lad være med at røre ved nålen og sæt ikke hætten på igen.
English: Q. What if there is a drop of liquid on the tip of the needle when I remove the base cap?
Danish: Hvad nu hvis der er en dråbe væske på spidsen af nålen, når jeg drejer hætten af?
English: • The teal plunger rod should show through the body of the syringe.
Danish: • Den blågrønne stempelstang skal kunne ses gennem sprøjtecylinderen.
English: 1 Uncap the Pen
Danish: 1 fyldt pen
English: What you need to know before you use Emgality Do not use Emgality:
Danish: Det skal du vide, før du begynder at bruge Emgality
English: Pruritus Rash
Danish: Pruritus Udslæt
English: In patients failing two or more prophylactic treatments, the treatment difference was4.48 days (p < 0.001) between 120 mg and placebo and -1.86 days (p < 0.01) between 240 mg and placebo.
Danish: Hos patienter, der havde oplevet svigt af mindst to profylaktiske behandlinger, var behandlingsdifferencen -4,48 dage (p < 0,001) mellem 120 mg og placebo, og -1,86 dage (p < 0,01) mellem 240 mg og placebo.
English: The syringe must not be shaken.
Danish: Injektionssprøjten må ikke omrystes.
English: EU/1/18/1330/001 EU/1/18/1330/002 EU/1/18/1330/005
Danish: EU/1/18/1330/005
English: 100 % Responders Percentage, % P-value
Danish: 100% respondenter Procentdel, % P-værdi
English: Leave the needle cap on until you are ready to inject.
Danish: Lad nålehætten sidde på, indtil du er klar til at foretage indsprøjtningen.
English: In patients who failed one or more prophylactic treatments for efficacy reasons, the treatment difference for the reduction of mean monthly MHDs observed between galcanezumab 120 mg and placebo was -3.54 days (p < 0.001) and between galcanezumab 240 mg and placebo -1.37 days (p < 0.05).
Danish: Hos patienter, der havde oplevet effektsvigt af en eller flere profylaktiske behandlinger, var behandlingsdifferencen (fald i gennemsnittet af månedlige MHD'er) -3,54 dage (p < 0,001) mellem galcanezumab 120 mg og placebo, og -1,37 dage (p < 0,05) mellem galcanezumab 240 mg og placebo.
English: Grey Syringe Plunger
Danish: Blågrøn stempelstang
English: EU/1/18/1330/003 EU/1/18/1330/004 EU/1/18/1330/006
Danish: EU/1/18/1330/006
English: Thumb Pad
Danish: Balden Lår
English: Belgique/België/Belgien
Danish: Belgique/België/Belgien Eli Lilly Benelux S.A./N.V.
English: Finger Grips
Danish: Gråt stempel
English: Emgality 120 mg solution for injection in pre-filled pen galcanezumab
Danish: Emgality 120 mg injektionsvæske, opløsning i fyldt pen galcanezumab
English: Each pre-filled pen contains 120 mg of galcanezumab in 1 mL solution.
Danish: Hver fyldt pen indeholder 120 mg galcanezumab i 1 ml opløsning.
English: Emgality 120 mg solution for injection in pre-filled syringe galcanezumab
Danish: Emgality 120 mg injektionsvæske, opløsning i fyldt injektionssprøjte galcanezumab
English: Injection Button
Danish: Blågrøn Injektionsknap
English: Store in a refrigerator.
Danish: SÆRLIGE OPBEVARINGSBETINGELSER Opbevares i køleskab.
English: Emgality 120 mg solution for injection in pre-filled pen
Danish: LÆGEMIDLETS NAVN Emgality 120 mg injektionsvæske, opløsning i fyldt pen
English: Instructions for use
Danish: BRUGERVEJLEDNING
English: Each pre-filled syringe contains 120 mg of galcanezumab in 1 mL solution.
Danish: Hver fyldt injektionssprøjte indeholder 120 mg galcanezumab i 1 ml opløsning.
English: Parts of the Emgality Syringe
Danish: INFORMATION I BRAILLESKRIFT Emgality
English: What Emgality looks like and contents of the pack
Danish: Udseende og pakningsstørrelser
English: Each pre-filled pen contains 120 mg of galcanezumab in 1 mL.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hver fyldt pen indeholder 120 mg galcanezumab i 1 ml.
English: EU/1/18/1330/001 (1 pre-filled pen) EU/1/18/1330/002 (3 pre-filled pens) EU/1/18/1330/005 (2 pre-filled pens)
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/18/1330/001 (1 fyldt pen)
English: Emgality 120 mg solution for injection in pre-filled syringe
Danish: LÆGEMIDLETS NAVN Emgality 120 mg injektionsvæske, opløsning i fyldt injektionssprøjte
English: Excipients
Danish: Nålehætte
English: EVOLVE-1 - Episodic Migraine
Danish: Tabel 2 Effekt og patient-rapporterede udfald EVOLVE-1 - Episodisk migræne
English: If you are breast-feeding or are planning to breast-feed, talk to your doctor before using this medicine.
Danish: Tal med lægen, inden du bruger dette lægemiddel, hvis du ammer eller planlægger at amme.
English: Bottom/ Needle end
Danish: Bund/ Nåle-ende
English: Teva Sweden AB
Danish: Sverige Teva Sweden AB
English: Your doctor will tell you the dose to take.
Danish: Deres læge vil fortælle Dem hvilken dosis De skal tage.
English: Your doctor will check whether Glidipion is working 3 to 6 months after you start taking it.
Danish: Din læge vil undersøge om Glidipion virker 3 til 6 måneder efter du starter med at tage det.
English: However if you miss a dose, just carry on with the next dose as normal.
Danish: Hvis du glemmer en dosis, skal du dog bare fortsætte med den næste dosis som normalt.
English: Use in children under 18 years is not recommended.
Danish: Børn og unge Brug hos børn under 18 år anbefales ikke.
English: If you experience any of these, especially if you are over the age of 65, seek medical advice straight away.
Danish: Hvis du oplever nogle af disse symptomer, især hvis du er over 65 år, skal du søge lægehjælp med det samme.
English: The Prescriber Guide should highlight the following:
Danish: Ordinationsguiden skal fremhæve følgende:
English: - if you have a problem with your liver or heart.
Danish: - hvis du har problemer med lever eller hjerte.
English: Take Glidipion daily as prescribed.
Danish: Tag Glidipion dagligt som foreskrevet.
English: • Patient selection criteria including that Pioglitazone should not be used as first line therapy and emphasising the need for regular review of treatment benefit.
Danish: • Patient udvælgelseskriterier, herunder at Pioglitazon ikke bør anvendes som første linje behandling og understreget behovet for regelmæssige gennemgange af behandlingens fordele.
English: Bladder cancer
Danish: Blærekræft
English: Prior to distribution of the prescriber guide in each Member State, the MAH must agree the content and format of the educational material, together with a communication plan, with the national competent authority.
Danish: Forud for uddelingen af den ordinerede lægeguide i hvert enkelt medlemsland, skal indehaveren af markedsføringstilladelsen godkende indholdet og formatet af undervisningsmaterialet, samt en kommunikationsplan, sammen med den nationale kompetente myndighed.
English: • This educational pack is aimed at strengthening awareness of important identified risks of bladder cancer and heart failure and the overall recommendations intended to optimise the benefit-risk margin at the patient level.
Danish: • Denne uddannelsespakke har til formål at styrke bevidstheden om vigtige identificerede risici for blærekræft og hjertesvigt, og de samlede anbefalinger har til formål at optimere risk-benefit marginen på patientniveau.
English: Glidipion helps control the level of sugar in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.
Danish: Glidipion hjælper med at kontrollere sukkerniveauet i dit blod, hvis du har type 2-diabetes, ved at hjælpe din krop til bedre at udnytte den insulin, kroppen producerer.
English: There may be an increased possibility of becoming pregnant because you may ovulate again when you take Glidipion.
Danish: Der kan være større sandsynlighed for at blive gravid, fordi du kan få ægløsning igen, når du tager Glidipion.
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Danish: Hvis du er gravid eller ammer, har mistanke om at du er gravid, eller planlægger at blive gravid, skal du spørge din læge til råds, før du tager dette lægemiddel.
English: Environmental Risk Assessment: no environmental impact is anticipated from the clinical use of pioglitazone.
Danish: Miljørisikovurdering: Der forventes ingen virkninger på miljøet fra klinisk anvendelse af pioglitazon.
English: Combination use with insulin should be considered with caution in the elderly because of increased risk of serious heart failure.
Danish: Samtidig brug med insulin skal overvejes med forsigtighed hos ældre på grund af en øget risiko for alvorlig hjerteinsufficiens.
English: You should swallow the tablets with a glass of water.
Danish: Du skal sluge tabletterne med et glas vand.
English: Not known (frequency cannot be estimated from the available data) - increase in liver enzymes - allergic reactions
Danish: Ikke kendt (hyppigheden kan ikke estimeres ud fra tilgængelige data) - forhøjede leverenzymer - allergiske reaktioner
English: Do not use Glidipion after the expiry date which is stated on the carton and the blister pack after the word “EXP”.
Danish: Brug ikke Glidipion efter den udløbsdato, der står på pakningen af ”EXP”.
English: If you are following a diabetic diet, you should continue with this while you are taking Glidipion.
Danish: Hvis du følger en diabetesdiæt, skal du fortsætte med denne, mens du tager Glidipion.
English: Epidemiological studies have also suggested a small increased risk of bladder cancer in diabetic patients treated with pioglitazone, although not all studies identified a statistically significant increased risk.
Danish: Epidemiologiske studier har også antydet en lille øget risiko for blærekræft hos diabetespatienter behandlet med pioglitazon, selv om ikke alle studier fandt en statistisk signifikant øget risiko.
English: • The physician educational pack should contain: The Summary of Product Characteristics, package leaflet, and a Prescriber Guide.
Danish: • Den lægelige uddannelsespakke skal indeholde: Produktresumé, indlægsseddel samt en Ordinationsguide.
English: - if you have liver disease.
Danish: - hvis du en har leversygdom.
English: Frequencies are defined as: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare
Danish: Hyppigheden er defineret som: Meget almindelig (≥ 1/10); almindelig (≥ 1/100 til < 1/10); ikke almindelig (≥ 1/1.000 til < 1/100); sjælden (≥ 1/10.000 til < 1/1.000); meget sjælden (< 1/10.000); ikke kendt (kan ikke estimeres ud fra forhåndenværende data).
English: However, the marketing authorisation holder shall submit periodic safety update reports for this medicinal product if the product is included in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and published on the European medicines web-portal.
Danish: Indehaveren af markedsføringstilladelsen skal imidlertid fremsende PSUR'er, såfremt lægemidlet bliver inkluderet på listen over EU-referencedatoer (EURD list), som fastsat i artikel 107c, stk. 7, i direktiv 2001/83/EF og offentliggjort på den europæiske webportal for lægemidler
English: Allergic reactions have been reported (frequency not known) in patients taking Glidipion.
Danish: Der er rapporteret om allergiske reaktioner (hyppighed ikke kendt) hos patienter, der tager Glidipion.
English: If you stop using Glidipion, your blood sugar may go up.
Danish: Hvis du holder op med at tage Glidipion, kan dit blodsukker stige.
English: Glidipion can be taken with or without food.
Danish: Glidipion kan tages med eller uden et måltid.
English: If ALT levels remain > 3 X the upper limit of normal, therapy should be discontinued.
Danish: Hvis ALT-niveauer forbliver > 3 X den øvre normale grænse, bør behandlingen seponeres.
English: Pioglitazone is indicated as second or third line treatment of type 2 diabetes mellitus as described below:
Danish: Pioglitazon er indiceret som anden- eller tredjevalgsbehandling af type 2-diabetes mellitus som beskrevet nedenfor:
English: - if you have blood in your urine that your doctor has not checked.
Danish: - hvis du har eller har haft blærekræft - hvis du har blod i urinen som din læge endnu ikke har undersøgt.
English: These effects were independent of pioglitazone's effects on glycaemia and were statistically significant different to glibenclamide.
Danish: Disse effekter var uafhængige af pioglitazons virkning på glykæmi og var statistisk signifikant forskellige fra glibenclamid.
English: 220 Hafnarfjörður Iceland
Danish: 220 Hafnarfjördur
English: In light of age-related risks (especially bladder cancer, fractures and heart failure), the balance of benefits and risks should be considered carefully both before and during treatment in the elderly.
Danish: I lyset af aldersrelaterede risici (især blærekræft, frakturer og hjerteinsufficiens) bør fordele og ulemper overvejes med forsigtighed både før og under behandlingen af ældre.
English: If you take Glidipion with other medicines for diabetes, it is more likely that your blood sugar could fall below the normal level (hypoglycaemia).
Danish: Hvis du tager Glidipion sammen med anden diabetesmedicin, er der en større risiko for, at dit blodsukker falder til under det normale niveau (hypoglykæmi).
English: This study showed an increase in reports of heart failure, however this did not lead to an increase in mortality in this study.
Danish: Dette studie viste et øget antal rapporter om hjertesvigt, men det førte ikke til en øget dødelighed i studiet.
English: - The active substance is pioglitazone.
Danish: - Det aktive stof er pioglitazon.
English: When Glidipion is taken in combination with other medicines used to treat diabetes (such as insulin, chlorpropamide, glibenclamide, gliclazide, tolbutamide) your doctor will tell you whether you need to take a smaller dose of your medicines.
Danish: Når Glidipion tages sammen med andre lægemidler, der anvendes til behandling af sukkersyge (f.eks. insulin, chlorpropamid, glibenclamid, gliclazid, tolbutamid), vil din læge give dig besked på, om du skal tage en mindre dosis af lægemidlerne.
English: After excluding patients in whom exposure to study drug was less than one year at the time of diagnosis of bladder cancer, there were 7 cases (0.06%) on pioglitazone and 2 cases (0.02%) in control groups.
Danish: Efter udelukkelse af patienter for hvem eksponeringen for det undersøgte lægemiddel var under et år ved diagnosen af blærekræft, var der 7 tilfælde (0,06 %) med pioglitazon og 2 tilfælde (0,02 %) i kontrolgrupperne.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE Æske
English: Reykjavíkurvegi 76-78 220 Hafnarfjörður Iceland
Danish: Reykjavíkurvegi 76-78 220 Hafnarfjördur Island
English: In clinical studies, patients have taken pioglitazone at higher than the recommended highest dose of 45 mg daily.
Danish: I kliniske forsøg har patienter taget pioglitazon i højere doser end den anbefalede maksimale dosis på 45 mgdagligt.
English: Your doctor will ask you to have blood tests periodically during treatment with Glidipion.
Danish: Din læge vil bede dig om at få taget blodprøver periodevis, mens du er i behandling med Glidipion.
English: No information is available from dialysed patients, therefore pioglitazone should not be used in such patients.
Danish: Der er ingen tilgængelige data fra dialysepatienter, og derfor bør pioglitazon ikke anvendes til denne patientkategori.
English: Before you start taking Glidipion you will have a blood sample taken to check your liver function.
Danish: Før du begynder at tage Glidipion, vil du få taget en blodprøve til kontrol af leverfunktionen.
English: Risk factors for bladder cancer should be assessed before initiating pioglitazone treatment (risks include age, smoking history, exposure to some occupational or chemotherapy agents e.g. cyclophosphamide or prior radiation treatment in the pelvic region).
Danish: Risikofaktorer for blærekræft bør vurderes før initiering af behandling med pioglitazon (risici inkluderer alder, rygehistorie, eksponering for visse faglige eller kemoterapeutiske agenter f.eks. cyclophosphamid eller forudgående strålebehandling i bækkenområdet).
English: When treating patients who have at least one risk factor for development of congestive heart failure (e.g. prior myocardial infarction or symptomatic coronary artery disease or the elderly), physicians should start with the lowest available dose and increase the dose gradually.
Danish: Ved behandling af patienter, der har mindst én risikofaktor for udvikling af hjerteinsufficiens (f.eks. tidligere hjerteinfarkt eller symptomgivende koronar arteriel sygdom eller ældre), bør lægen starte med den lavest tilgængelige dosis, som derefter øges gradvist.
English: Glidipion has no or negligible effect on the ability to drive and use machines.
Danish: Glidipion påvirker ikke eller kun i ubetydelig grad evnen til at føre motorkøretøj og betjene maskiner.
English: Pioglitazone tablets are taken orally once daily with or without food.
Danish: Pioglitazon-tabletter indtages peroralt en gang dagligt alene eller i forbindelse med et måltid.
English: After initiation of therapy with pioglitazone, patients should be reviewed after 3 to 6 months to assess adequacy of response to treatment (e.g. reduction in HbA1c).
Danish: Efter initiering af behandlingen med pioglitazon bør patienten revurderes efter 3 til 6 måneder for at vurdere tilstrækkeligheden af respons på behandlingen (fx reduktion i HbA1c).
English: The European Medicines Agency has waived the obligation to submit the results of studies with pioglitazone in all subsets of the paediatric population in Type 2 Diabetes Mellitus.
Danish: Det Europæiske Lægemiddelagentur har dispenseret fra kravet om fremlæggelse af resultaterne af studier med pioglitazon i alle undergrupper af den pædiatriske population ved type 2-diabetes mellitus (se pkt.
English: Talk to your doctor before you start to take this medicine: - if you retain water (fluid retention) or have heart failure problems and in particular if you are over 75 years old.
Danish: Kontakt lægen, før du tager Glidipion: - hvis du har vand i kroppen (ødemer) eller har problemer med hjertesvigt, specielt hvis du er over 75 år.
English: If ALT levels are increased to 3 X upper limit of normal during pioglitazone therapy, liver enzyme levels should be reassessed as soon as possible.
Danish: Hvis ALT-niveauer øges til 3 X den øvre normale grænse under pioglitazonbehandling, bør leverenzymniveauer vurderes igen så hurtigt som muligt.
English: For the 14, 28, 56, 84 and 98 tablets pack sizes, you can check the day on which you last took a tablet of Glidipion by referring to the calendar printed on the blister.
Danish: For tabletterne i 14, 28, 56, 84 og 98-styks pakningerne kan du tjekke på hvilken ugedag, du sidst tog din tablet Glidipion ved at se på kalenderen trykt på blisterpakningen.
English: The MAH shall provide an educational pack targeting all physicians who are expected to prescribe/use Pioglitazone.
Danish: Indehaveren af markedsføringstilladelsen skal udarbejde en uddannelsespakke målrettet alle læger, der kan forventes at ordinere/anvende Pioglitazon.
English: However, certain medicines are especially likely to affect the amount of sugar in your blood: - gemfibrozil (used to lower cholesterol) - rifampicin (used to treat tuberculosis and other infections) Tell your doctor or pharmacist if you are taking any of these.
Danish: Visse typer medicin er dog særlig tilbøjelige til at påvirke blodsukkeret: - gemfibrozil (til at sænke kolesteroltallet) - rifampicin (mod tuberkulose og andre infektioner) Fortæl det til lægen eller på apoteket, hvis du får et af disse lægemidler.
English: Cases of bladder cancer were reported more frequently in a meta-analysis of controlled clinical trials with pioglitazone (19 cases from 12506 patients, 0.15%) than in control groups (7 cases from 10212 patients, 0.07%) HR=2.64 (95% CI 1.11-6.31, P=0.029).
Danish: I metaanalyser ved kontrollerede kliniske forsøg med pioglitazon blev tilfælde af blærekræft rapporteret hyppigere (19 tilfælde ud af 12506 patienter, 0,15 %) end i kontrolgrupperne (7 tilfælde ud af 10212, 0,07 %) HR = 2,64 (95 % CI 1,11-6,31, P = 0,029).
English: OTHER (FOR CALENDARISED PACKS SIZES OF 14, 28, 56, 84 AND 98 TABLETS ONLY)
Danish: ANDET (KUN FOR KALENDERISEREDE PAKNINGSSTØRRELSER MED 14, 28, 56, 84 OG 98 TABLETTER)
English: Very common (may affect more than 1 in 10 people) - decreased blood sugar (hypoglycaemia)
Danish: Meget almindelige (kan forekomme hos mere end 1 ud af 10 personer) - lavt blodsukker (hypoglykæmi)
English: Pioglitazone treatment may be initiated at 15 mg or 30 mg once daily.
Danish: Pioglitazon behandling kan initieres med 15 mg eller 30 mg én gang dagligt.
English: It is an anti-diabetic medicine used to treat type 2 (non-insulin dependent) diabetes mellitus, when metformin is not suitable or has failed to work adequately.
Danish: Det er en antidiabetisk medicin, der anvendes til behandling af type 2-diabetes mellitus (ikke-insulinkrævende sukkersyge), når metformin ikke er egnet eller ikke har haft tilstrækkelig virkning.
English: Glidipion contains pioglitazone.
Danish: Glidipion indeholder pioglitazon.
English: Signs and symptoms include blood in your urine, pain when urinating or a sudden need to urinate.
Danish: Tegn og symptomer er blod i urinen, smerter ved vandladning eller pludselig vandladningstrang.
English: - The other ingredients are lactose monohydrate, hydroxypropylcellulose, carmellose calcium and magnesium stearate.
Danish: - De øvrige indholdsstoffer er lactosemonohydrat, hydroxypropylcellulose, carmellosecalcium og magnesiumstearat.
English: Postmarketing, bone fractures have been reported in both male and female patients (see section 4.4).
Danish: Der er efter markedsføring indberettet knoglefrakturer hos både mandlige og kvindelige patienter (se pkt.
English: Almost all subjects (95%) were receiving cardiovascular medicinal products (beta blockers, ACE inhibitors, angiotensin II antagonists, calcium channel blockers, nitrates, diuretics, aspirin, statins, fibrates).
Danish: Næsten alle patienterne (95 %) var i behandling med lægemidler for kardiovaskulær sygdom (betablokkere, ACEhæmmere, angiotensin II-antagonister, calciumantagonister, nitrater, diuretika, acetylsalisylsyre, statiner og fibrater).