FrancophonIA/ELRC3.0 huggingface dataset:
English: If you are having a blood test ensure your doctor knows you are taking this medicine.
Slovenian: Če vam bodo preiskali kri, poskrbite, da bo zdravnik vedel, da jemljete to zdravilo.
English: - Inability to pass urine.
Slovenian: - Nezmožnost odvajanja urina.
English: For sublingual use only.
Slovenian: Samo za sublingvalno uporabo.
English: Patients at higher risk are those with respiratory impairment or reduced respiratory reserve.
Slovenian: Bolniki z večjim tveganjem so tisti z okvaro dihal ali zmanjšano dihalno rezervo.
English: The expiry date refers to the last day of that month.
Slovenian: Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca;
English: Depending on individual sensitivity, the clinical picture is determined by the degree of respiratory depression.
Slovenian: Odvisno od občutljivosti posameznika klinično sliko določi stopnja depresije dihanja.
English: Primary attention should be given to obstruction of airways and the necessity of assisted or controlled ventilation.
Slovenian: Primarno pozornost je treba nameniti obstrukciji dihalnih poti in potrebi po asistiranem ali nadzorovanem predihavanju.
English: Dzuveo with alcohol
Slovenian: Dzuveo z alkoholom
English: In that case, the opioid antagonist can be administered repeatedly or by infusion.
Slovenian: V tem primeru se lahko opioidni antagonist da večkrat ali z infuzijo.
English: Caution should be exercised in patients on these concomitant medicinal products and they should be closely monitored.
Slovenian: Previdnost je potrebna pri bolnikih, ki jemljejo ta zdravila sočasno, in jih je treba skrbno spremljati.
English: Signs and symptoms
Slovenian: Znaki in simptomi:
English: Medicines should not be thrown away via wastewater or household waste.
Slovenian: Zdravila ne smete zavreči v odpadne vode ali med gospodinjske odpadke.
English: Because of these risks, concomitant prescribing with these sedative medicines should be reserved for patients for whom alternative treatment options are not possible, or when sufentanil is used in an emergency setting.
Slovenian: Zaradi teh tveganj mora biti sočasno predpisovanje teh pomirjeval pridržano za bolnike, pri katerih niso mogoče alternativne možnosti zdravljenja, ali kadar se sufentanil uporablja v nujnih primerih.
English: • The method of use of the device;
Slovenian: • postopkom za uporabo pripomočka;
English: Sufentanil does not induce histamine release.
Slovenian: Sufentanil ne inducira sproščanja histamina.
English: - Allergic reactions, itching of the skin.
Slovenian: - Alergijske reakcije, srbenje kože.
English: Email: edgar.fenzl@fgk-rs.de
Slovenian: 20 E-poštni naslov:edgar.fenzl@fgk-rs.de
English: Rest the SDA lightly on the patient's teeth or lips.
Slovenian: Aplikator rahlo naslonite na bolnikove zobe ali ustnice.
English: Pharmacotherapeutic group: Anesthetics, opioid anesthetics, ATC Code: N01AH03.
Slovenian: Farmakoterapevtska skupina: Anestetiki, opioidni anestetiki, ATC-koda: N01AH03.
English: • The minimum dosing interval of one sublingual tablet per hour, in order to prevent / minimise the important identified risk of respiratory depression and the important potential risk of overdose;
Slovenian: • najkrajšim odmernim intervalom ene podjezične tablete na uro, da se prepreči/zmanjša pomembno ugotovljeno tveganje za depresijo dihanja in pomembno potencialno tveganje za preveliko odmerjanje;
English: Dzuveo is provided in a disposable single-dose applicator, to be administered by a healthcare provider as needed by the individual patient, but no more than once every hour, resulting in a maximum dose of 720 micrograms /day.
Slovenian: Zdravilo Dzuveo je na voljo v aplikatorju za enkratno uporabo z enkratnim odmerkom in ga mora dajati zdravstveni delavec, kakor je potrebno pri posameznem bolniku, vendar ne več kot enkrat na uro, s čimer je dosežen največji odmerek 720 mikrogramov/dan.
English: The applicator, with the tablet inside, is enclosed within a pouch.
Slovenian: Aplikator, v katerem je tableta, je zaprt v vrečki.
English: The applicator will help your healthcare provider place one tablet under your tongue.
Slovenian: Aplikator bo zdravstvenemu delavcu v pomoč pri postavitvi ene tablete pod vaš jezik.
English: After your treatment the medical staff will dispose of the applicator accordingly.
Slovenian: Po zdravljenju bo medicinsko osebje aplikator ustrezno odstranilo.
English: The maximum daily dose is 720 micrograms (24 tablets per day).
Slovenian: 720 mikrogramov (24 tablet na dan).
English: Similar effects with other potent CYP3A4 inhibitors (e. g. itraconazole, ritonavir) cannot be excluded.
Slovenian: Podobnih učinkov pri drugih močnih zaviralcih CYP3A4 (npr. itrakonazolu, ritonaviru) ni mogoče izključiti.
English: Some insoluble excipients of the tablet may remain in the mouth after dissolution is complete; this is normal and does not indicate lack of absorption of sufentanil from the tablet.
Slovenian: Nekatere netopne pomožne snovi v tableti lahko po popolni raztopitvi ostanejo v ustih; to je normalno in ne pomeni pomanjkanja absorpcije sufentanila iz tablete.
English: Your doctor or nurse will ensure that: - this medicine is not used after the expiry date which is stated on the label and carton after EXP.
Slovenian: Vaš zdravnik ali medicinska sestra bo poskrbel, da: - se to zdravilo ne bo uporabljalo po datumu izteka roka uporabnosti, ki je naveden na nalepki in škatli poleg oznake „UPORABNO DO“.
English: This may range from hypoventilation to respiratory arrest.
Slovenian: Ta se lahko giblje od hipoventilacije do zastoja dihanja.
English: Do not drink alcohol while using Dzuveo.
Slovenian: Med uporabo zdravila Dzuveo ne pijte alkohola.
English: Repeat antagonist administration may be required as the duration of respiratory depression may last longer than the duration of the effect of the antagonist (see section 4.9).
Slovenian: Potrebna bo morda ponavljajoča se uporaba antagonistov, saj lahko depresija dihanja traja dlje, kot traja učinek antagonista (glejte poglavje 4.9).
English: Children and adolescents Dzuveo should not be used in children and adolescents below 18 years.
Slovenian: Zdravila Dzuveo se ne sme uporabljati pri otrocih in mladostnikih, mlajših od 18 let.
English: The frequencies are defined as:
Slovenian: Pogostnosti so opredeljene kot: Zelo pogosti Pogosti
English: - Ketoconazole, which is used for the treatment of fungal infections this medicine may have an effect on the way in which your body breaks down sufentanil.
Slovenian: - ketokonazol, ki se uporablja za zdravljenje glivičnih okužb; to zdravilo lahko vpliva na to, kako vaše telo razgrajuje sufentanil;
English: Dzuveo will be available in cartons of 5 and 10.
Slovenian: Zdravilo Dzuveo je na voljo v škatlah po 5 in 10.
English: Sufentanil is excreted in human milk to such an extent that effects on the breastfed newborns/infants are likely.
Slovenian: Sufentanil se v materino mleko izloča v tolikšni meri, da so verjetni učinki na dojene novorojence/otroke.
English: Gastrointestinal effects
Slovenian: Gastrointestinalni učinki
English: Patients were predominantly female (63%), mean age was 41 years (range 18-74 years), BMI 15.8 to 53.5 kg/m2, race was predominately White (69%) and Black or African American (21%).
Slovenian: Bolniki so bili pretežno ženske (63 %), povprečna starost je bila 41 let (razpon od 18 do 74 let), ITM je bil od 15,8 do 53,5 kg/m², rasa je bila pretežno bela (69 %) in črna ali afroameriška (21 %).
English: The Ames test revealed no mutagenic activity of sufentanil.
Slovenian: Amesov preskus ni pokazal nobene mutagene aktivnosti sufentanila.
English: Fertility and early embryonic development studies were conducted in male and female rats.
Slovenian: Vpliv na sposobnost razmnoževanja Študije plodnosti in zgodnjega embrionalnega razvoja so bile izvedene na samcih in samicah podgan.
English: All effects of sufentanil can immediately and completely be blocked by administration of a specific antagonist such as naloxone.
Slovenian: Vse učinke sufentanila se lahko takoj in popolnoma blokira z dajanjem specifičnega antagonista, npr. naloksona.
English: What Dzuveo is and what it is used for
Slovenian: Kaj je zdravilo Dzuveo in za kaj ga uporabljamo
English: For Dzuveo, population pharmacokinetic analysis showed an effect of age, with an 18% decrease in clearance in the elderly (above 65 years of age).
Slovenian: Dzuveo se je pri populacijski farmakokinetični analizi pokazal vpliv starosti z 18-odstotnim zmanjšanjem očistka pri starejših (starejših od 65 let).
English: The tablets dissolve under your tongue and should not be chewed, or swallowed because the tablet is not effective for pain relief unless it is allowed to dissolve under your tongue.
Slovenian: Tablete se pod jezikom raztopijo in jih ne smete žvečiti ali pogoltniti, saj tableta ni učinkovita za lajšanje bolečin, razen če se lahko raztopi pod jezikom.
English: Sufentanil may cause respiratory depression (see section 4.4) and also suppresses the cough reflex.
Slovenian: Sufentanil lahko povzroči depresijo dihanja (glejte poglavje 4.4) in tudi zavira refleks kašlja.
English: The most serious side effects are severe breathing problems, like slow and shallow breathing, which may even lead to you stopping breathing.
Slovenian: Najresnejši neželeni učinki so hude težave z dihanjem, npr. počasno in plitvo dihanje, ki lahko privedejo celo do prenehanja dihanja.
English: This medicine must be given to you by a doctor or a nurse using the single-dose administration device.
Slovenian: To zdravilo vam mora dati zdravnik ali medicinska sestra z uporabo naprave za dajanje v enkratnem odmerku.
English: Frequency not known (frequency cannot be estimated from the available data): Severe allergic reactions (anaphylactic shock), convulsions (fits), coma, small pupil size, redness of the skin.
Slovenian: Pogostnost neznana (pogostnosti ni mogoče oceniti iz razpoložljivih podatkov): Hude alergijske reakcije, (anafilaktični šok), konvulzije (krči), koma, majhne zenice, rdečina kože.
English: Do not use if the Single Dose Applicator (SDA) is damaged.
Slovenian: Ne uporabljajte, če je aplikator z enkratnim odmerkom (SDA) poškodovan.
English: Maximum concentrations of sufentanil are achieved approximately 60 minutes after a single dose; this is shortened to approximately 40 minutes following repeated hourly dosing.
Slovenian: Največje koncentracije sufentanila so dosežene približno 60 minut po enkratnem odmerku; to se po večkratnem urnem odmerjanju skrajša na približno 40 minut.
English: • Detailed instruction on how to handle overdose / respiratory depression
Slovenian: • Podrobna navodila o tem, kako ravnati pri prevelikem odmerku/depresiji dihanja.
English: What Dzuveo is and what it is used for What you need to know before you use Dzuveo How to use Dzuveo
Slovenian: Kaj je zdravilo Dzuveo in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Dzuveo Kako jemati zdravilo Dzuveo
English: What you need to know before you use Dzuveo Do not use Dzuveo:
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Dzuveo Zdravila Dzuveo ne uporabljajte:
English: Your healthcare provider will dispose of any waste according to hospital policies.
Slovenian: Vse odpadke bo skladno s politikami bolnišnice zavrgel vaš zdravstveni delavec.
English: Intracranial pressure
Slovenian: Intrakranialni tlak
English: It measures 3 mm in diameter and is enclosed within a single-dose applicator (labelled [sublingual tablet]).
Slovenian: Meri 3 mm in je zaprta v aplikatorju za enojen odmerek (označen z [sublingual tablet]).
English: The safety and efficacy of sufentanil in children and adolescents below 18 years have not been established.
Slovenian: Pediatrična populacija Varnost in učinkovitost sufentanila pri otrocih in mladostnikih, mlajših od 18 let, nista bili dokazani.
English: - Other medicines which are also taken sublingually (placed under the tongue where they dissolve) or medicines which take effect in your mouth (e.g. nystatin, a liquid or pastilles you hold in your mouth to treat fungus infections), as the effect on Dzuveo has not been studied.
Slovenian: - druga zdravila, ki se tudi jemljejo podjezično (vstavijo pod jezik, kjer se raztopijo), ali ki učinkujejo v ustih (npr. nistatin, tekočina ali pastile, ki jih držite v ustih za zdravljenje glivičnih okužb), saj učinka na zdravilo Dzuveo niso proučevali;
English: Injury, poisoning and procedural complications
Slovenian: Poškodbe, zastrupitve in zapleti pri posegih
English: It can increase the risk of experiencing severe breathing problems.
Slovenian: Zdravilo lahko poveča tveganje za pojav hudih težav z dihanjem.
English: abdominal, bunionectomy).
Slovenian: abdominalna študija, bunionektomija).
English: Tell the patient to touch their tongue to the roof of their mouth if possible.
Slovenian: Bolniku naročite, naj se, če je mogoče, z jezikom dotakne neba v ustih.
English: Interaction with other sublingually administered products or products intended to dilute/establish an effect in the oral cavity were not evaluated and simultaneous administration should be avoided.
Slovenian: Drugo Medsebojnega delovanja z drugimi sublingvalno danimi zdravili ali zdravili, ki se raztopijo/povzročijo učinek v ustni votlini, niso ovrednotili in se je treba izogibati njihovemu sočasnemu dajanju.
English: It is not recommended to use these medicines at the same time as Dzuveo.
Slovenian: Teh zdravil ni priporočljivo jemati sočasno z zdravilom Dzuveo.
English: Biotransformation takes place primarily in the liver and the small intestine.
Slovenian: Biotransformacija poteka predvsem v jetrih in tankem črevesju.
English: No specific dose adjustment is required in elderly patients.
Slovenian: Pri starejših bolnikih odmerka ni treba posebej prilagajati.
English: - Slow or difficult breathing (including when sleeping), Nose bleeds, hiccups.
Slovenian: Počasno ali oteženo dihanje (tudi med spanjem), krvavitev iz nosu, kolcanje.
English: Sufentanil should not be used in pregnancy, because it crosses the placenta and the foetal respiratory center is sensitive to opiates.
Slovenian: Sufentanila se ne sme uporabljati v nosečnosti, ker prehaja skozi posteljico, plodov dihalni center pa je občutljiv za opiate.
English: Following long-term treatment sufentanil may cause withdrawl symptoms in the newborn.
Slovenian: Po dolgotrajnem zdravljenju lahko sufentanil povzroči odtegnitvene simptome pri novorojenčku.
English: Neoplasm benign, malignant and unspecified (including cysts and polyps)
Slovenian: Benigne, maligne in neopredeljene novotvorbe (vključno s cistami in polipi)
English: A medically monitored setting must have equipment and personnel trained to detect and manage hypoventilation, and availability of supplemental oxygen and opioid antagonists, such as naloxone.
Slovenian: Medicinsko nadzorovano okolje mora imeti opremo in osebje, opremljeno za prepoznavanje in odpravljanje hipoventilacije, v njem pa morajo biti na voljo dodatni kisik in opioidni antagonisti, npr. nalokson.
English: - Regularly prescribed opioid medicine (e.g. morphine, codeine, fentanyl, hydromorphone, oxycodone).
Slovenian: - redno predpisovano opioidno zdravilo (npr. morfin, kodein, fentanil, hidromorfon, oksikodon);
English: 3-4 Ballyboggan Industrial Estate, Ballyboggan Road, Finglas, Dublin 11, Ireland.
Slovenian: 3-4 Ballyboggan Industrial Estate Ballyboggan Road Finglas, Dublin 11, Irska
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from sufentanil therapy taking into account the benefit of breast feeding for the child and the benefit of therapy for the woman.
Slovenian: Odločiti se je treba med prenehanjem dojenja in prenehanjem/prekinitvijo zdravljenja s sufentanilom, pri čemer je treba pretehtati prednosti dojenja za otroka in prednosti zdravljenja za mater.
English: Risk from concomitant use of sedative medicines such as benzodiazepines or related medicinal products
Slovenian: Tveganje zaradi sočasne uporabe pomirjeval, npr. benzodiazepinov ali sorodnih zdravil
English: Sufentanil may increase plasma serotonin level and its concomitant use with other serotoninergic agents may increase the risk of serotonin syndrome.
Slovenian: Sufentanil lahko poviša raven serotonina v plazmi, njegova sočasna uporaba z drugimi serotoninergičnimi učinkovinami pa lahko poveča tveganje serotoninskega sindroma.
English: Ketoconazole, a potent CYP3A4 inhibitor, can significantly increase the systemic exposure to sublingual sufentanil (maximal plasma levels (Cmax) increase of 19%, overall exposure to the active substance (AUC) increase of 77% and prolong the time to reach maximum concentration by 41%.
Slovenian: Ketokonazol, močan zaviralec citokroma CYP3A4, lahko močno poveča sistemsko izpostavljenost podjezičnemu sufentanilu (povečanje največje plazemske koncentracije (Cmax) za 19 odstotkov, povečanje celotne izpostavljenosti učinkovini (PPK) za 77 odstotkov, podaljšanje časa za dosego največje koncentracije za 41 odstotkov.
English: - Increased heart rate, high blood pressure, low blood pressure.
Slovenian: - Pospešen srčni utrip, visok krvni tlak, nizek krvni tlak.
English: The recommended dose is a maximum of one 30 microgram sublingual tablet per hour.
Slovenian: Priporočeni odmerek je največ ena 30-mikrogramska podjezična tableta na uro.
English: Respiratory depression caused by sufentanil can be reversed by opioid antagonists.
Slovenian: Depresijo dihanja, ki jo povzroča sufentanil, se lahko odpravi z opioidnimi antagonisti.
English: The applicator is used as a placement aid for the healthcare professional to deliver the tablet under the tongue, on an as needed basis, per patient request, with a minimum of 1 hour between doses.
Slovenian: Aplikator se uporablja kot pomoč zdravstvenemu delavcu pri namestitvi tablete pod jezik, po potrebi na zahtevo bolnika, z najmanj eno uro razmika med odmerki.
English: - Headache, drowsiness, feeling sleepy.
Slovenian: - Glavobol, dremavost, občutek zaspanosti.
English: Similar CST½ values were observed following both single and repeated administration, demonstrating that there is a predictable and consistent duration of action after multiple dosing of the sublingual tablet.
Slovenian: Podobne vrednosti so bile opažene po enkratnem in večkratnem dajanju, kar dokazuje, da obstaja predvidljivo in dosledno trajanje delovanja po večkratnem odmerku podjezičnih tablet.
English: Patients on chronic opioid therapy or opioid addicts may require higher analgesic doses than contained in Dzuveo.
Slovenian: Bolniki s kronično opioidno terapijo ali opioidni odvisniki bodo morda potrebovali večje odmerke analgetikov, kot jih vsebuje zdravilo Dzuveo.
English: If swallowed, the oral bioavailability of Dzuveo is only 9% which would result in a subtherapeutic dose.
Slovenian: Če se zdravilo Dzuveo pogoltne, je njegova peroralna biološka uporabnost le 9 %, kar bi povzročilo subterapevtski odmerek.
English: After multiple administrations, a longer mean terminal half-life of 15.7 hours (range 2.4 to 42.7 hours) was observed, owing to the higher plasma concentrations of sufentanil achieved after repeated dosing and due to the possibility to quantify these concentrations over a longer time period.
Slovenian: Po večkratnem dajanju so opazili daljši povprečni razpolovni čas terminalne faze, 15,7 ure (razpon od 2,4 do 42,7 ure), in sicer zaradi dosežene večje plazemske koncentracije sufentanila po večkratnem odmerjanju in zaradi možnosti za količinsko opredelitev teh koncentracij v daljšem časovnem obdobju.
English: The most serious adverse reaction of sufentanil is respiratory depression, which occurred at a rate of 0.6% in sufentanil clinical trials.
Slovenian: Najresnejši neželeni učinek sufentanila je depresija dihanja, ki se je v kliničnih preskušanjih sufentanila pojavila s stopnjo 0,6 odstotka.
English: Very rare <1/10,000 Not known Cannot be estimated from the available data.
Slovenian: Neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov)
English: Sufentanil may cause hypotension, especially in hypovolemic patients.
Slovenian: Sufentanil lahko, zlasti pri hipovolemičnih bolnikih, povzroči hipotenzijo.
English: Prior to the launch of Dzuveo in each Member State (MS), the Marketing Authorisation Holder (MAH) must agree about the content and format of the educational materials, including communication media, distribution modalities, and any other aspects of the programme, with the National Competent Authority (NCA).
Slovenian: Pred prihodom zdravila Dzuveo na trg v posamezni državi članici mora imetnik dovoljenja za promet z zdravilom z nacionalnim pristojnim organom sprejeti dogovor o vsebini in obliki izobraževalnega gradiva, vključno z mediji komunikacije, načini distribucije in vsemi drugimi vidiki programa.
English: In humans the potency is 7 to 10-fold higher than fentanyl and 500 to 1,000-fold higher than morphine (per oral).
Slovenian: Pri človeku ima od 7- do 10-krat močnejši učinek kot fentanil in od 500- do 1000-krat močnejši učinek kot morfin (peroralno).
English: The shorter duration of activity of the opiate antagonist compared to that of sufentanil should be taken into account.
Slovenian: Treba je upoštevati krajše trajanje učinka opiatnih antagonistov v primerjavi s trajanjem učinka sufentanila.
English: Sufentanil may cause respiratory depression, for which the degree/severity is dose related.
Slovenian: Sufentanil lahko povzroči depresijo dihanja, katere stopnja/resnost je odvisna od odmerka.
English: This medicine may also cause changes in levels of platelets (which help your blood to clot), magnesium, protein, sugar, fats, phosphates and plasma in your blood which can only be identified through a blood test.
Slovenian: To zdravilo lahko povzroči tudi spremembe v koncentraciji trombocitov (ki pomagajo pri strjevanju krvi), magnezija, beljakovin, sladkorja, maščob, fosfatov in plazme v krvi, kar je mogoče prepoznati samo s preiskavo krvi.
English: Sufentanil is used to treat sudden moderate-to-severe pain in adults in medically monitored settings such as a hospital.
Slovenian: Sufentanil se uporablja za zdravljenje nenadne zmerne do hude bolečine pri odraslih v medicinsko nadzorovanih okoljih, npr. v bolnišnici.
English: Sublingual tablet.
Slovenian: Podjezična tableta.
English: This should be considered when prescribing or administering sufentanil where there is concern about an increased risk of misuse, abuse or diversion.
Slovenian: To je treba upoštevati pri predpisovanju ali dajanju sufentanila, če obstaja možnost povečanega tveganja nepravilne uporabe, zlorabe ali uporabe v druge namene.
English: Other symptoms that may occur are loss of consciousness, coma, cardiovascular shock and muscle rigidity.
Slovenian: Drugi simptomi, ki se lahko pojavijo, so izguba zavesti, koma, kardiovaskularni šok in rigidnost mišic.
English: The MAH shall ensure that in each MS where Dzuveo is marketed, all HCPs (i.e. physicians, hospital pharmacists, and nurses) who are expected to prescribe / administer the product are provided with a Healthcare Professional Guide, outlining critical information for the safe and effective use of Dzuveo, including:
Slovenian: Imetnik dovoljenja za promet z zdravilom mora v vsaki državi članici, v kateri se zdravilo Dzuveo trži, poskrbeti, da vsi zdravstveni delavci (tj. zdravniki, bolnišnični farmacevti in medicinske sestre), za katere se pričakuje, da bodo predpisovali/aplicirali zdravilo, prejmejo vodnik za zdravstvene delavce, ki opisuje ključne informacije za varno in učinkovito uporabo zdravila
English: With Dzuveo, first dose clearance in the typical patient of weight 78.5 kg and age 47 years is 84.2 L/hr.
Slovenian: Pri zdravilu Dzuveo je očistek po prvem odmerku pri tipičnem bolniku s telesno maso 78,5 kg in starostjo 47 let 84,2 l/h.
English: You should only drive and use machines if sufficient time has elapsed after your last dose of Dzuveo.
Slovenian: Voziti in upravljate stroje smete samo, če je od zadnjega odmerka zdravila Dzuveo minilo dovolj časa.
English: - Pain in the back, chest or other body parts, pain in the extremities.
Slovenian: Bolečina v hrbtu, prsnem košu ali drugem delu telesa, bolečina v udih.
English: Direct effects of sufentanil on myocardial function were not observed.
Slovenian: Neposredni učinki sufentanila na delovanje miokarda niso bili opaženi.