FrancophonIA/ELRC3.0 huggingface dataset:
English: Dose of ritonavir (mg)
Maltese: Doża ta' ritonavir (mg)
English: Ritonavir is an orally active peptidomimetic inhibitor of the HIV-1 and HIV-2 aspartyl proteases.
Maltese: Ritonavir huwa impeditur attiv peptidomimetiku tal-protejaż aspartil HIV-1 u HIV-2 li jittieħed millħalq.
English: Ethinylestradiol
Maltese: Ethinyl estradiol
English: Yellow, capsule shaped film-coated tablet, approximately 19.1 mm x 10.2 mm, debossed with ‘M163' on one side and plain on the other side.
Maltese: Pillola miksija b'rita, safra, b'forma ta' kapsula, b'daqs ta' madwar 19.1 mm × 10.2 mm, imnaqqxa b'‘M163' fuq naħa waħda u xejn fuq in-naħa l-oħra.
English: (For caution on parenterally administered midazolam, see section 4.5.
Maltese: (Sabiex tiġi eżerċitata kawtela meta midazolam jiġi mgħoti parenteralment, ara sezzjoni 4.5).
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Maltese: Sensittività eċċessiva għas-sustanza attiva jew għal xi eċċipjenti elenkati fis-sezzjoni 6.1.
English: Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness: very common (> 1/10); common (> 1/100 to < 1/10); uncommon (> 1/1,000 to < 1/100); rare (> 1/10,000 to < 1/1,000); not known (cannot be estimated from the available data).
Maltese: F'kull klassifikazzjoni ta' frekwenza, l-effetti mhux mixtieqa huma preżentati f'ordni li tibda mill-iktar effetti serji u tispiċċa fl-inqas effetti serji: komuni ħafna (≥1/10); komuni (≥1/100 sa <1/10); mhux komuni (≥1/1000 sa <1/100); rari (≥1/10,000 sa <1/1,000); mhux magħrufa (ma jistgħux jiġu kkalkolati mill-informazzjoni eżistenti).
English: 200 q12 h Tipranavir Ritonavir
Maltese: 200 q12h Tipranavir
English: A controlled study completed in 1996 with ritonavir as add-on therapy in HIV-1 infected patients extensively pre-treated with nucleoside analogues and baseline CD4 cell counts ≤ 100 cells/μl showed a reduction in mortality and AIDS defining events.
Maltese: Studju kkontrollat komplet fl-1996 li sar b'ritonavir bħala terapija addizzjonali fuq pazjenti infettati blHIV-1 u li kienu preċedentement ikkurati estensivament b'analogi ta' nukleòside u b'għadd ta' ċellulli tal-linja bażi CD4 ≤100 ċelluli/µl, urew tnaqqis fil-mortalità u fl-avvenimenti li jiddefinixxu l-AIDS.
English: Each film-coated tablet contains 87.75 mg of sodium.
Maltese: Kull pillola miksija b'rita fiha 87.75 mg ta' sodium.
English: Alprazolam metabolism was inhibited following the introduction of ritonavir.
Maltese: Il-metaboliżmu ta' alprazolam ġie imwaqqaf meta ritonavir ġie introdott.
English: HMG Co-A reductase inhibitors
Maltese: Impedituri HMG Co-A Reductase Atorvastatin,
English: Systemic corticosteroid effects including Cushing's syndrome and adrenal suppression (plasma cortisol levels were noted to be decreased 86% in the above study) have been reported in patients receiving ritonavir and inhaled or intranasal fluticasone propionate; similar effects could also occur with other corticosteroids metabolised by CYP3A e.g., budesonide and triamcinolone.
Maltese: Effetti tal-corticosteroids sistematiċi inkluż is-sindromu Cushing u soppressjoni adrenali (fl-istudju t'hawn fuq ġie nnotat li l-livelli tal-cortisol fil-plażma naqsu 86%) ġew rapportati f'pazjenti li jieħdu ritonavir u li jiġbdu f'imnifsejhom jew idaħħlu fl-imnieħer fluticasone propionate; jistgħu jirriżultaw effetti simili b'corticosteroids oħra metabolati b' CYP3A e.ż.,budesonide u triamcinolone.
English: Increased plasma concentrations of avanafil (see sections 4.4. and 4.5).
Maltese: Żieda fil-konċentrazzjoni fil-plażma ta' avanafil (ara sezzjoni 4.4 u 4.5).
English: Ritonavir Mylan contains sodium
Maltese: Ritonavir Mylan fih is-sodium
English: PDE5 inhibitor
Maltese: Impeditur PDE5
English: ↑ 20 to 39%
Maltese: ↑ >20 darba ↑ 87%
English: 500 q12 h ↑ 145% ↑ 22% The AUC and Cmax of the 2-hydroxy metabolite were decreased 15 and 67%, respectively.
Maltese: L-AUC u Cmax tal-metabolat 2-hydroxy ġew imnaqqsa b' 15 u 67%, rispettivament.
English: Sedatives/hypnotics Clorazepate, diazepam, estazolam, flurazepam, oral and parenteral midazolam
Maltese: Mediċina Sedattiva/ Ipnotika Clorazepate, diazepam, estazolam, flurazepam, midazolam mittieħed mill-ħalq u parenterali
English: Increased plasma concentrations of lomitapide (see section 4.5).
Maltese: Żieda fil-konċentrazzjoni fil-plażma ta' lomitapide (ara sezzjoni 4.5).
English: Low doses of ritonavir have shown profound effects on the pharmacokinetics of other protease inhibitors (and other products metabolised by CYP3A4) and other protease inhibitors may influence the pharmacokinetics of ritonavir (see section 4.5).
Maltese: Dożi baxxi ta' ritonavir urew effetti profondi fuq il-farmakokinetika ta' impedituri protejaż oħra (u prodotti oħra metabolizzati b'CYP3A4), u impedituri oħra protejaż jistgħu jinfluwenzaw ilfarmakokinetika ta' ritonavir (ara sezzjoni 4.5).
English: Endothelin antagonists Bosentan
Maltese: Mediċini li jinblukkaw endothelin Bosentan
English: Refer to the colchicine prescribing information.
Maltese: Irreferi wkoll għall-informazzjoni ta' preskrizzjoni ta' colchicine.
English: Increased plasma concentrations of vardenafil (see sections 4.4. and 4.5).
Maltese: Żieda fil-konċentrazzjoni fil-plażma ta' vardenafil (ara sezzjoni 4.4 u 4.5).
English: Pruritus, rash (including erythematous and maculopapular)
Maltese: Komuni ħafna Prurite, raxx (li jinkludi dawk tat-tip erythematous u maculopapular)
English: In intent to treat analyses, 72% and 36% of patients achieved reduction in plasma HIV-1 RNA of ≤ 400 copies/ml at Week 16 and 104, respectively.
Maltese: F'analażi tal-intenzjoni biex tfejjaq,72% u 36% tal-pazjenti laħqu tnaqqis tal-HIV-1 RNA fil-plażma ta' ≤400 kopja/mL f'Ġimgħa numru 16 u 104, rispettivament.
English: Antianginal Ranolazine
Maltese: Mediċina għal kontra l-anġina Ranolazine
English: Clorazepate, diazepam, estazolam, flurazepam, oral midazolam and triazolam
Maltese: Clorazepate, diazepam, estazolam, flurazepam, midazolam mittieħed mill-ħalq u triazolam
English: 1 Based on parallel group comparison.
Maltese: 1 Ibbażat fuq paragun ta' gruppi paralleli.
English: PR interval prolongation
Maltese: Titwil tal-intervall PR
English: amphetamine or amphetamine derivatives; antibiotics (e.g. erythromycin, clarithromycin); anticancer treatments (e.g. abemaciclib, afatinib, ceritinib, dasatinib, ibrutinib, nilotinib, venetoclax, vincristine, vinblastine); anticoagulants (e.g. rivaroxaban, vorapaxar, warfarin); antidepressants (e.g. amitriptyline, desipramine, fluoxetine, imipramine, nefazodone, nortriptyline, paroxetine, sertraline, trazodone); antifungals (e.g. ketoconazole, itraconazole); antihistamines (e.g. loratadine, fexofenadine); antiretroviral medicines including HIV-protease inhibitors (amprenavir, atazanavir, darunavir, fosamprenavir, indinavir, nelfinavir, saquinavir, tipranavir) non-nucleoside reverse transcriptase inhibitors (NNRTI) (delavirdine, efavirenz, nevirapine), and others (didanosine, maraviroc, raltegravir, zidovudine); anti-tuberculosis medicine (bedaquiline and delamanid); antiviral medicine used to treat chronic hepatitis C virus (HCV) infection in adults (e.g. glecaprevir/pibrentasvir and simeprevir); anxiety medicine, buspirone; asthma medicine, theophylline, salmeterol; atovaquone, a medicine used to treat a certain type of pneumonia and malaria; buprenorphine, a medicine used for the treatment of chronic pain; bupropion, a medicine used to help you stop smoking; epilepsy medicines (e.g. carbamazepine, divalproex, lamotrigine, phenytoin); heart medicines (e.g. disopyramide, mexiletine and calcium channel antagonists such as amlodipine, diltiazem and nifedipine); immune system (e.g. cyclosporine, tacrolimus, everolimus); levothyroxine (used to treat thyroid problems)
Maltese: (eż. glecaprevir/pibrentasvir u simeprevir); - mediċina għal kontra l-ansjetà, buspirone; - mediċina għal kontra l-ażżma, theophylline, salmeterol; - atovaquone, mediċina użata għall-kura ta' ċertu tip ta' pnewmonja u malarja; - buprenorphine, mediċina użata għall-kura ta' uġigħ kroniku; - bupropion, mediċina użata biex tgħinek tieqaf tpejjep; - mediċini għall-epilessija (e.ż. carbamazepine, divalproex, lamotrigine, phenytoin); - mediċini għall-qalb (e.ż. disopyramide, mexiletine u mediċini li jaħdmu kontra l-kanali tal kalċju bħal amlodipine, diltiazem u nifedipine); - is-sistema immunitarja (e.ż. cyclosporine, tacrolimus, everolimus); - levothyroxine (użat għall-kura ta' problemi tat-tirojde) - morfina u mediċini simili għall-morfina użati għall-kura ta' uġigħ kbir ħafna (e.ż. methadone,
English: Analgesics Buprenorphine
Maltese: Mediċini Analġesiċi Buprenorphine
English: Anticonvulsants Carbamazepine
Maltese: Mediċini għal kontra l-Konvulżjoni Carbamazepine
English: The protein binding of ritonavir in human plasma is approximately 98 - 99% and is constant over the concentration range of 1.0 - 100 μg/ml.
Maltese: It-tweħħil ta' ritonavir mal-proteini tad-demm fil-plażma tal-bniedem huwa ta' bejn wieħed u ieħor 98 - 99% u huwa kostanti tul il-medda ta' konċentrazzjoni ta' bejn 1.0 - 100 µg/mL.
English: Serum concentrations may be increased due to P-glycoprotein, BCRP and OATP1B inhibition by ritonavir.
Maltese: P-glycoprotein, BCRP u OATP1B minn ritonavir.
English: In an interaction study of single-dose bedaquiline and multiple dose lopinavir/ritonavir, the AUC of bedaquiline was increased by 22%.
Maltese: Fi studju ta' interazzjoni b'doża waħda ta' bedaquiline u doża multipli ta' lopinavir/ritonavir, l-AUC ta' bedaquiline żdiedet bi 22%.
English: The isopropylthiazole oxidation metabolite (M-2) is the major metabolite and has antiviral activity similar to that of parent compound.
Maltese: Il-metabolit ta' ossidifikazzjoni ta' isopropylthiazole (M-2) huwa l-metabolit prinċipali u għandhu attività antiretrovirali simili għal dik tal-prodott mediċinali prinċipali (parent drug).
English: Symptoms of infection - inform your doctor immediately.
Maltese: - Sintomi ta' infezzjoni - informa lit-tabib tiegħek immedjatament.
English: Ritonavir dosed as an antiretroviral agent
Maltese: Ritonavir dożat bħala aġent antiretrovirali
English: This medicinal product contains 87.75 mg sodium per tablet, equivalent to 4.4% of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Maltese: Dan il-prodott mediċinali fih 87.75 mg ta' sodium f'kull pillola, ekwivalenti għal 4.4% tal-ammont massimu rakkomandat mill-WHO ta' 2 g sodium.
English: ↑ 2.5 fold ↔
Maltese: ↑ bi 2.5 drabi
English: Medicinal product interactions - Ritonavir with protease inhibitors
Maltese: Interazzjonijiet tal-Prodotti Mediċinali - Ritonavir ma' Aġenti Antiretrovirali minbarra Impedituri Protejaż
English: • severe or life threatening skin reaction including blisters (Stevens Johnson syndrome, toxic epidermal necrolysis)
Maltese: • reazzjonijiet fil-ġilda severi jew li jpoġġu l-ħajja fil-periklu, inklużi bżieżaq (issindromu Stevens Johnson, nekroliżi tossika tal-epidermide)
English: Ritonavir was the first protease inhibitor (approved in 1996) for which efficacy was proven in a study with clinical endpoints.
Maltese: Ritonavir kien l-ewwel impeditur protejaż (approvat fl-1996) li għalih kienet pruvata l-effikaċja fi studju kliniċi finalizzati.
English: PDE5 inhibitors
Maltese: Impedituri PDE5
English: Increased plasma concentrations of sildenafil.
Maltese: Żieda fil-konċentrazzjoni filplażma ta' sildenafil.
English: 0.125, single dose
Maltese: 0.125, doża waħda 200, 4 dożi
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent
Maltese: Ritonavir dożat biex iżid l-effett farmakokinetiku jew bħala agent antiretrovirali
English: Metabolic parameters
Maltese: Parametri tal-metaboliċi
English: Iron oxide yellow (E172) Silica, colloidal anhydrous Polysorbate 80
Maltese: Iron oxide yellow (E172)
English: Atorvastatin is less dependent on CYP3A for metabolism.
Maltese: Atorvastatin huwa inqas dipendenti fuq is-CYP3A għall-metaboliżmu.
English: ↔ ↑ 4 fold
Maltese: ↑ b' 4 darbiet
English: 1 Based on cross-study comparison to 400 mg atazanavir once daily alone.
Maltese: 1 Ibbażat fuq studju komparattiv li jinqeleb ma' 400 mg atazanavir darba kuljum waħdu.
English: 0.4 single oral dose
Maltese: 0.4 doża waħda orali
English: This medicine contains 87.75 mg of sodium in each tablet.
Maltese: Dan il-prodott mediċinali fih 87.75 mg ta' sodium f'kull pillola.
English: Hepatitis (including increased AST, ALT, GGT), blood bilirubin increased (including jaundice)
Maltese: Epatite (li tinkludi żieda fl-AST, ALT, GGT), żieda filbilirubin fid-demm (li tinkludi suffejra)
English: Other medicines and Ritonavir Mylan
Maltese: Mediċini oħra u Ritonavir Mylan
English: if you are currently taking any of the following medicines: astemizole or terfenadine (commonly used to treat allergy symptoms - these medicines may be available without prescription); amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, quinidine (used to correct irregular heartbeats); dihydroergotamine, ergotamine (used to treat migraine headache); ergonovine, methylergonovine (used to stop excessive bleeding that may occur following childbirth or an abortion); clorazepate, diazepam, estazolam, flurazepam, triazolam or oral (taken by mouth) midazolam (used to help you sleep and/or relieve anxiety); clozapine, pimozide, (used to treat abnormal thoughts or feelings); quetiapine (used to treat schizophrenia, bipolar disorder and major depressive disorder); lurasidone (used to treat depression); ranolazine (used to treat chronic chest pain [angina]); pethidine, piroxicam, propoxyphene (used to relieve pain); cisapride (used to relieve certain stomach problems);
Maltese: - jekk bħalissa qiegħed tieħu xi waħda minn dawn il-mediċini segwenti: - astemizole jew terfenadine (issoltu użata biex tikkura sintomi ta' allergija - dawn ilmediċini jistgħu jiġu akkwistati mingħajr riċetta tat-tabib); - amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, quinidine (użati sabiex jikkoreġu taħbit irregolari tal-qalb); - dihydroergotamine, ergotamine (użati għall-kura tal-migranja); - ergonovine, methylergonovine (użati biex iwaqqfu ħruġ eċċessiv ta' demm li jista' jkun hemm wara l-ħlas jew wara abort); - clorazepate, diazepam, estazolam, flurazepam, triazolam jew midazolam orali (mittieħed mill-ħalq) (użati biex jgħinuk torqod u/jewinaqqsu l-ansjetà); - clozapine, pimozide (użati biex jikkuraw ħsibijiet jew emozzjonijiet li m'humiex normali); - quetiapine (użat biex jikkura skiżofrenija, disturb bipolari u disturb dipressiv maġġuri); - lurasidone (użat biex jittratta dipressjoni); - ranolazine (użat biex jittratta uġigħ fis-sider kroniku [anġina]); - pethidine, piroxicam, propoxyphene (użati biex itaffu l-uġigħ);
English: The recommended dose of ritonavir is 600 mg (6 tablets) twice daily (total of 1,200 mg per day) by mouth.
Maltese: Id-doża rrakkomandata tal-pilloli miksija b'rita ritonavir hija ta' 600 mg (6 pilloli) darbtejn kuljum (total ta' 1200 mg kuljum) mill-ħalq.
English: • if Ritonavir Mylan is used to boost the effects of certain other anti-HIV medicines the typical dose for adults is 1 to 2 tablets once or twice daily.
Maltese: • jekk Ritonavir Mylan huwa użat biex iżid l-effetti ta' ċerti mediċini oħra għal kontra l-HIV, iddoża tipika għall-adulti hi minn 1 sa 2 pilloli darba jew darbtejn kuljum.
English: Concomitant use of ritonavir with lomitapide is contraindicated (see prescribing information for lomitapide) (see section 4.3).
Maltese: L-użu konkomitanti ta' ritonavir ma' lomitapide huwa kontraindikat (ara l-informazzjoni dwar kif jiġi preskritt lomitapide) (ara sezzjoni 4.3).
English: Abnormal liver function tests, hepatitis (inflammation of the liver), and rarely jaundice, have been reported in patients taking ritonavir.
Maltese: Testijiet abnormali tal-funzjoni tal-fwied, epatite (infjammazzjoni tal-fwied) u rarament is-suffejra, ġew rapportati f'pazjenti li jieħdu ritonavir.
English: Ritonavir may induce glucuronidation and oxidation by CYP1A2, CYP2C8, CYP2C9 and CYP2C19 thereby increasing the biotransformation of some medicinal products metabolised by these pathways, and may result in decreased systemic exposure to such medicinal products, which could decease or shorten their therapeutic effect.
Maltese: Ritonavir jista' jikkawża glukuronidazzjoni u ossidazzjoni permezz ta' CYP1A2, CYP2C8, CYP2C9 u CYP2C19 u għalhekk iżid il-biotrasformazzjoni ta' xi prodotti mediċinali li huma metabolizzati minn dawn il-passaġġi, u jista' jirriżulta fi tnaqqis talesponiment sistemiku għal dawn il-prodotti mediċinali, li jista' jnaqqas l-effett terapewtiku jew iqassar il-perijodu tal-effett terapewtiku tagħhom.
English: Serum concentrations of ibrutinib may be increased due to CYP3A inhibition by ritonavir, resulting in increased risk for toxicity including risk of tumor lysis syndrome.
Maltese: Il-konċentrazzjonijiet ta' ibrutinib fis-serum jistgħu jiżdiedu minħabba inibizzjoni ta' CYP3A minn ritonavir, li jirriżulta f'riskju akbar ta' tossiċità inkluż riskju ta' sindromu ta' lisi tat-tumur.
English: Increased plasma concentrations of amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, quinidine.
Maltese: Żieda fil-konċentrazzjoni fil-plażma ta' amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, quinidine.
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jiroveci pneumonia.
Maltese: Eżempji relevati huma retinite ikkawzata minn cytomegalovirus, infezzjonijiet generalised u/jew infezzjonijiet fokali kkawżati minn mycobacteria, u pnewmonja kkawżata minn Pneumocystis jiroveci.
English: Serum levels of ritonavir may be affected by select co-administered medicinal products (e.g. delavirdine, efavirenz, phenytoin and rifampicin).
Maltese: Il-livelli fis-serum ta' ritonavir jistgħu jiġu affetwati minn prodotti mediċinali speċifiċi li jingħataw flimkien ma' ritonavir (e.ż. delavirdine, efavirenz, phenytoin u rifampicin).
English: Ritonavir dosed as a pharmacokinetic enhancer
Maltese: Ritonavir mogħti biex iżid l-effett farmakokinetiku
English: Ritonavir binds to both human alpha 1-acid glycoprotein (AAG) and human serum albumin (HSA) with comparable affinities.
Maltese: Ritonavir jeħel b'affinitajiet komparabbli, kemm ma' alpha 1-acid glycoprotein (AAG) uman, kif ukoll mas-serum tal-albumina (HSA) tal-bniedem.
English: In an open label trial completed in 1998 in HIV infected, clinically stable children there was a significant difference (p = 0.03) in the detectable RNA levels in favour of a triple regimen (ritonavir, zidovudine and lamivudine) following 48 weeks treatment.
Maltese: Fi prova open label kompleta fl-1998 fuq tfal klinikament stabbli infettati bl-HIV, kien hemm, wara kura ta' 48 ġimgħa, differenza sinifikanti (p=0.03) fil-livelli traċċabbli ta' RNA favur dożaġġ triplu (ritonavir, zidovudine u lamivudine).
English: 0.5 single IV dose
Maltese: 0.5 doża waħda
English: These effects are thought to represent induction of bupropion metabolism.
Maltese: Dawn l-effetti huma meqjusa li jirrapreżentaw induzzjoni tal-metaboliżmu ta' bupropion.
English: However, the AUC of the M-2 metabolite was approximately 3% of the AUC of parent compound.
Maltese: Iżda l-AUC tal-metabolit M-2 kien bejn wieħed u ieħor 3% tal-AUC tal-prodott mediċinali prinċipali.
English: Elevated norpethidine concentrations may increase the risk of CNS effects (e.g., seizures), see section 4.3.
Maltese: Konċentrazzjoni għolja ta' norpethidine jistgħu jżidu r-riskju tal-effetti tas-CNS (e.ż. attakki tal-epilessija), ara sezzjoni 4.3.
English: For patients with renal impairment, a clarithromycin dose reduction should be considered: for patients with creatinine clearance of 30 to 60 ml/min the dose should be reduced by 50%, for patients with creatinine clearance less than 30 ml/min the dose should be reduced by 75%.
Maltese: Għal pazjenti li jbatu minn indeboliment renali għandu jiġi kkunsidrat tnaqqis fid-doża ta' clarithromycin: għal pazjenti li għandhom tneħħija tal-krejatina ta' minn 30 sa 60 mL/min id-doża għandha tiġi mnaqqsa b'50%, għal pazjenti li għandhom tneħħija tal-krejatina ta' inqas minn 30 mL/min id-doża għandha tiġi mnaqqsa b' 75%.
English: Proton pump inhibitors and H2-receptor antagonists Proton pump inhibitors and H2-receptor antagonists (e.g. omeprazole or ranitidine) may reduce concentrations for co-administered protease inhibitors.
Maltese: L-impedituri tal-pompa tal-proton u antagonisti ta' riċetturi tal-H2 (e.ż. omeprazole jew ranitidine) jistgħu jnaqqsu l-konċentrazzjonijiet għall-impedituri protejaż meta jingħataw flimkien.
English: The most frequently used nucleosides in this study were zidovudine, stavudine, didanosine and zalcitabine.
Maltese: L-iktar nukleòsidi użati frekwentement f'dan l-istudju kienu zidovudine, stavudine, didanosine u zalcitabine.
English: 100q12h Darunavir
Maltese: 600, doża waħda 100 q12 h Darunavir
English: Pharmacotherapeutic group: antivirals for systemic use, protease inhibitors ATC code: J05AE03.
Maltese: Kategorija farmakoterapewtika: antiretrovirali għall-użu sistematiku, impedituri protejaż Kodiċi ATC:
English: MARKETING AUTHORISATION NUMBER(S) EU/1/17/1242/004
Maltese: TAL-AWTORIZZAZZJONI GĦAT-TQEGĦID FIS-SUQ EU/1/17/1242/004
English: Phenytoin may decrease serum levels of ritonavir.
Maltese: Phenytoin jista' jnaqqas il-livelli tas-serum ta' ritonavir.
English: NAME OF THE MEDICINAL PRODUCT Ritonavir Mylan 100 mg film-coated tablets ritonavir
Maltese: Informazzjoni għall-utent Ritonavir Mylan 100 mg pilloli miksija b'rita ritonavir
English: 100 q12 h Indinavir3 Ritonavir
Maltese: 100 q12 h Indinavir3
English: What Ritonavir Mylan is and what it is used for Ritonavir Mylan contains the active substance ritonavir.
Maltese: Ritonavir Mylan fih is-sustanza attiva ritonavir.
English: Paediatric populations The safety profile of ritonavir in children 2 years of age and older is similar to that seen in adults.
Maltese: L-profil tas-sigurtà ta' ritonavir fit-tfal ta' sentejn u anzjani huwa simili għal dak li deher fl-adulti.
English: Maraviroc may be given with ritonavir to increase the maraviroc exposure.
Maltese: Maraviroc jista' jingħata flimkien ma' ritonavir biex iżid l-espożizzjoni ta' maraviroc.
English: In vitro and in vivo studies have demonstrated that ritonavir is a potent inhibitor of CYP3A- and CYP2D6- mediated biotransformations.
Maltese: Studji in vitro u in vivo urew li ritonavir huwa impeditur potenti ta' bijotrasformazzjonijiet medjati b'CYP3A u CYP2D6.
English: Ritonavir is a protease inhibitor used to control HIV infection.
Maltese: Ritonavir huwa impeditur protejaż użat biex jikkontrolla l-infezzjoni tal-HIV.
English: Rare: may affect up to 1 in 1,000 people
Maltese: Rari jistgħu jaffetwaw sa 1 f 1,000 persuni
English: The effects of ritonavir (alone or combined with other antiretroviral agents) on biological markers of disease activity such as CD4 cell count and viral RNA were evaluated in several studies involving HIV-1 infected patients.
Maltese: L-effetti ta' ritonavir (waħdu jew flimkien ma' aġenti antietrovirali oħra) fuq werrejja bijoloġiċi talattivita' tal-mard, bħal għadd ta' ċelluli CD4 u RNA virali, ġew evalwati f'diversi studji li kienu jinvolvu pazjenti infettati bl-HIV-1.
English: Renal and urinary disorders
Maltese: Indeboliment renali akut
English: Due to the risk of bedaquiline related adverse events, co-administration should be avoided.
Maltese: Minħabba r-riskju ta' reazzjonijiet avversi relatati ma' bedaquiline, ko-amministrazzjoni għandha tiġi evitata.
English: This is equivalent to 4.4% of the recommended maximum daily dietary intake of sodium for an adult.
Maltese: Dan huwa ekwivalenti għal 4.4% talammont massimu rakkomandat ta' sodium li għandu jittieħed kuljum mad-dieta minn adult.
English: HMG co-A reductase inhibitors Atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin
Maltese: Fluvastatin, Lovastatin, Pravstatin, Rosuvastatin, Simvastatin