FrancophonIA/ELRC3.0 huggingface dataset:
English: The ACTIVE-A study (N=7,554) was a multicenter, randomized, double-blind, placebo-controlled study which compared clopidogrel 75 mg/day + ASA (N=3,772) to placebo + ASA (N=3,782).
Danish: ACTIVE-A-studiet (N = 7.554) var et multicenter, randomiseret, dobbeltblindt, placebokontrolleret studie, som sammenlignede clopidogrel 75 mg / dag + ASA (N = 3.772) med placebo + ASA (N =3.782).
English: Microcrystalline cellulose Stearic acid
Danish: Mikrokrystallinsk cellulose Stearinsyre
English: The safety and efficacy of clopidogrel have been evaluated in 5 double-blind studies involving over 88,000 patients: the CAPRIE study, a comparison of clopidogrel to ASA, and the CURE, CLARITY, COMMIT and ACTIVE-A studies comparing clopidogrel to placebo, both medicinal products given in combination with ASA and other standard therapy.
Danish: Sikkerheden og effekten af clopidrogrel er blevet evalueret i 5 dobbeltblindede studier, der omfattede mere end 88.000 patienter i CAPRIE-studiet, hvor clopidogrel sammenlignes med ASA, og CURE, CLARITY, COMMIT og ACTIVE-A-undersøgelserne, hvor clopidogrel sammenlignes med placebo, og hvor begge lægemidler gives i kombination med ASA eller anden standardterapi.
English: APOTEX ESPAÑA S.L.
Danish: España APOTEX ESPAÑA S.L.
English: Pharmacotherapeutic group: platelet aggregation inhibitors excl. heparin, ATC Code: B01AC-04.
Danish: Farmakoterapeutisk klassifikation: trombocytfunktionshæmmende midler eksklusive heparin, ATCkode: B01AC-04.
English: - signs of liver problems such as yellowing of the skin and/or the eyes (jaundice), whether or not associated with bleeding which appears under the skin as red pinpoint dots and/or confusion (see section 2 ‘Warnings and precautions').
Danish: Tegn på leverproblemer såsom gulfarvning af huden og/eller øjnene (gulsot), uanset om det sker i forbindelse med blødninger, som viser sig under huden som små røde prikker og/eller forvirring (se afsnit 2 'Advarsler og forsigtighedsregler')
English: Follow-up at one year was performed for 316 patients (98.1%) in the de-escalated DAPT group and 318 patients (98.5%) in the unchanged DAPT group.
Danish: Opfølgning efter et år blev udført for 316 patienter (98,1 %) i den de-eskalerede DAPT-gruppe og 318 patienter (98,5 %) i den uændrede DAPT-gruppe.
English: The primary endpoint was the occurrence of the composite of an occluded infarct-related artery on the predischarge angiogram, or death or recurrent MI before coronary angiography.
Danish: Det primære endepunkt var forekomsten af en kombination af okkluderede arterier, der var relateret til infarkt på angiogrammet før patienten blevudskrevet, dødsfald, eller ved gentaget MI før koronarangiografi.
English: Thrombolytics: the safety of the concomitant administration of clopidogrel, fibrin or non-fibrin specific thrombolytic agents and heparins was assessed in patients with acute myocardial infarction.
Danish: Trombolytika: Sikkerheden ved samtidig administration af clopidogrel, fibrin eller non- fibrinspecifikke trombolytiske midler og hepariner blev bedømt hos patienter med akut myokardieinfarkt.
English: The plasma concentrations of the active metabolite was 20% reduced (loading dose) and 14% reduced (maintenance dose) during concomitant treatment with pantoprazole 80 mg once daily.
Danish: Plasmakoncentrationerne af den aktive metabolit blev reduceret med 20 % (initial stabiliseringsdosismætningsdosis) og 14 % (vedligeholdelsesdosis) underved samtidig behandling med80 mg pantoprazol en gang daglig.
English: Patients with a confirmed diagnosis of acquired haemophilia should be managed and treated by specialists, and clopidogrel should be discontinued.
Danish: Patienter med en bekræftet diagnose på erhvervet hæmofili skal varetages ogbehandles af specialister, og clopidogrel skal seponeres.
English: Pharmathen S.A., 6 Dervenakion 15351 Pallini Attiki Greece
Danish: Pharmathen S.A., 6 Dervenakion 15351 Pallini Attiki Grækenland
English: Pink, round, biconvex, film-coated tablets.
Danish: Lyserøde, runde og bikonvekse filmovertrukne tabletter.
English: New cardiovascular events (primary endpoint) were prevented, with relative risk reductions of 22% (CI: 8.6, 33.4), 32% (CI: 12.8, 46.4), 4% (CI: -26.9, 26.7), 6% (CI: -33.5, 34.3) and 14% (CI: -31.6, 44.2), during the 0-1, 1-3, 3-6, 6-9 and 9-12 month study intervals, respectively.
Danish: Nye kardiovaskulære hændelser (primært endpoint) blev forebygget med relative risikoreduktioner på 22 % (CI: 8,6, 33,4) 32 % (CI: 12,8, 46,4), 4 % (CI: -26,9, 26,7), 6 % (CI:33,5, 34,3) og 14 % (CI: -31,6, 44,2), i løbet af studiets intervaller på henholdsvis 0-1, 1-3, 3-6,6-9 og 9
English: By preventing this clumping, antiplatelet medicinal products reduce the chances of blood clots forming (a process called thrombosis).
Danish: Ved at forebygge denne sammenklumpning nedsætter et blodpropopløsende præparat risikoen for, at der dannes blodpropper (en proces, der kaldes trombose).
English: Then, the recommended dose is one 75-mg tablet of Clopidogrel Apotex per day as described above.
Danish: Derefter er den anbefalede dosis 1 tablet Clopidogrel Apotex af 75 mg daglig, som beskrevet ovenfor.
English: TOPIC (Timing Of Platelet Inhibition after acute Coronary syndrome)
Danish: TOPIC(Timing Of Platelet Inhibition after acute Coronary syndrome- Tidsramme for trombocythæmning efter akut koronarsyndrom)
English: Clopidogrel significantly reduced the relative risk of death from any cause by 7% (p=0.029), and the relative risk of the combination of re-infarction, stroke or death by 9% (p=0.002), representing an absolute reduction of 0.5% and 0.9%, respectively.
Danish: Clopidogrel reducerede signifikant den relative dødsrisiko uanset årsag med 7 % (p = 0,029) og den relative risiko for kombinationen af re-infarkt, slagtilfæde eller død med 9 % (p = 0,002), hvilket repræsenterer en absolut reduktion på henholdsvis 0,5 % og 0,9 %.
English: Driving and using machines Clopidogrel Apotex is unlikely to affect your ability to drive or to use machines.
Danish: Trafik og arbejdssikkerhed: Det er usandsynligt, at Clopidogrel Apotex vil påvirke din evne til at køre eller betjene maskiner.
English: Blisters of white PVC/PE/PVDC-aluminium foil or PA/ALL/PVC-aluminium foil.
Danish: Blisterpakninger af hvidt PVC/PE/PVDC-aluminiumsfolie eller PA/ALL/PVC-aluminiumsfolie.
English: A significantly lower exposure to clopidogrel active metabolite and reduced platelet inhibition have been demonstrated in HIV-infected patients treated with ritonavir- or cobicistat-boosted anti-retroviral therapies (ART).
Danish: En signifikant lavere eksponering for clopidogrels aktive metabolit og reduceret trombocythæmning er påvist hos hiv-smittede patienter i behandling med ritonavir- eller cobicistat-boostet antiretroviral terapi (ART).
English: If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Clopidogrel Apotex.
Danish: Hvis du er gravid eller har mistanke om, at du er gravid, skal du fortælle det til din læge eller apoteket, før du tager Clopidogrel Apotex.
English: If Clopidogrel Apotex is supplied in all aluminium blisters, it does not require any special storage conditions.
Danish: Hvis Clopidogrel Apotex er pakket i blisterkort af ren aluminium kræves ingen særlige forholdsregler vedrørende opbevaringen.
English: Warnings and precautions If any of the situations mentioned below apply to you, you should tell your doctor before taking Clopidogrel Apotex:
Danish: Advarsler og forsigtighedsregler Hvis nogen af følgende situationer gælder for dig, skal du oplyse det til din læge, før du tagerClopidogrel Apotex:
English: The cumulative incidence of all bleeding events (BARC class 1 to 5) was 9% (114 events) in the guided de-escalation group versus 11% (137 events) in the control group (p=0.14).
Danish: Den kumulative incidens af alle blødningshændelser (BARC klasse 1 til 5) var 9 % (114 hændelser) i den guidede de-ekslaringsgruppe versus 11 % (137 hændelser) i kontrolgruppen (p=0,14).
English: However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 2 ‘Warnings and precautions').
Danish: Hvis du er bekymret over din blødning, skal du omgående kontakte din læge (se afsnit 2 'Advarsler og forsigtighedsregler').
English: Patients randomized in the ACTIVE program were those presenting with documented AF, i.e., either permanent AF or at least 2 episodes of intermittent AF in the past 6 months, and had at least one of the following risk factors: age 75 years or age 55 to 74 years and either diabetes mellitus requiring drug therapy, or documented previous MI or documented coronary artery disease; treated for systemic hypertension; prior stroke, transient ischaemic attack (TIA), or non-CNS systemic embolus; left ventricular dysfunction with left ventricular ejection fraction <45%; or documented peripheral vascular disease.
Danish: Patienter randomiseret i ACTIVE-programmet var dem, der blev præsenteret med dokumenteret AF, dvs. enten permanent AF eller mindst 2 episoder med intermitterende AF inden for de seneste6 måneder, og som havde mindst én af følgende risikofaktorer: alder ≥ 75 år eller alder 55 til 74 år og enten behandlingskrævende diabetes mellitus eller dokumenteret tidligere MI eller dokumenteretkoronararteriesygdom; behandlingskrævende systemisk hypertension; apopleksi, transitorisk cerebral iskæmi (TCI), eller non-CNS systemisk emboli i anamnesen; venstre ventrikel dysfunktion med venstre ventrikel uddrivningsfraktion <45% eller dokumenteret perifer vaskulær sygdom.
English: Clopidogrel significantly reduced the incidence of new ischaemic events (combined end point of myocardial infarction, ischaemic stroke and vascular death) when compared to ASA.
Danish: Clopidogrel reducerede signifikant forekomsten af nye iskæmiske tilfælde (kombineret endpoint, der omfattede myokardieinfarkt, iskæmisk slagtilfælde og vaskulær død) ved sammenligning med ASA.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency: http://www.ema.europa.eu/
Danish: Du kan finde yderligere oplysninger om dette lægemiddel på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu
English: Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/
Danish: Du kan finde yderligere oplysninger om dette lægemiddel på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu/.
English: The most common side effect reported with Clopidogrel Apotex is bleeding.
Danish: Den almindeligste bivirkning, der er set med Clopidogrel Apotex er blødning.
English: NSAIDs: in a clinical study conducted in healthy volunteers, the concomitant administration of clopidogrel and naproxen increased occult gastrointestinal blood loss.
Danish: NSAID'er: I et klinisk studie foretaget på raske forsøgspersoner øgede den samtidige administration af clopidogrel og naproxen okkult gastrointestinalt blodtab.
English: The decrease was associated with a 39% (loading dose) and 21% (maintenance dose) reduction of inhibition of platelet aggregation.
Danish: Denne nedgang var associeret med en 39 % (initial stabiliseringsdosismætningsdosis) og 21 % (vedligeholdelsesdosis) reduktion i trombocythæmning.
English: A total of 99.7% of patients received fibrinolytics (fibrin specific: 68.7%, non-fibrin specific: 31.1%), 89.5% heparin, 78.7% beta blockers, 54.7% ACE inhibitors and 63% statins.
Danish: En total på 99,7 % af patienterne fik fibrinolytika (fibrinspecifik: 68,7 %, non-fibrin specifik:31,1 %), 89,5 % fik heparin, 78,7 % betablokkere, 54,7 % ACE-hæmmere og 63 % statiner.
English: Medicinal products that are strong or moderate CYP2C19 inhibitors include for example omeprazole and esomeprazole, fluvoxamine, fluoxetine, moclobemide, voriconazole, fluconazole, ticlopidine, carbamazepine, and efavirenz.
Danish: Potente og moderate CYP2C19-hæmmere inkluderer for eksempel omeprazol og esomeprazol, fluvoxamin, fluoxetin, moclobemid, voriconazol, fluconazol, ticlopidin, carbamazepin og efavirenz.
English: This statistically significant difference was mainly driven by fewer bleeding events, with no difference reported in ischaemic endpoints (p=0.36), while BARC ≥2 bleeding occurred less frequently in the de-escalated DAPT group (4.0%) versus 14.9% in the unchanged DAPT group (p<0.01).
Danish: Denne statistisk signifikante forskel var hovedsagelig drevet af færre blødninghændelser, med ingen forskel rapporteret i iskæmiske endepunkter (p=0,36), mens BARC ≥2 blødning forekom mindre hyppigt i den de-eskalerede DAPTgruppe (4,0 %) versus 14,9 % i den uændrede DAPT-gruppe (p<0,01).
English: You have previously experienced a heart attack, stroke or have a condition known as peripheral arterial disease, or
Danish: Du tidligere har haft et hjerteanfald, apopleksi eller du har en sygdom kendt som perifere kredsløbsforstyrrelser, eller
English: In addition, IPA was 32% (24 hours) and 61% (Day 5), which were greater than in the poor metabolisers receiving the 300 mg/75 mg regimen,and were similar to the other CYP2C19 metaboliser groups receiving the 300 mg/75 mg regimen.
Danish: Desuden var IPA på 32 % (24 timer) og 61 % (dag 5), hvilket var større end hos poor metabolisers, der fik 300 mg/75 mg-regimet, og svarede til IPA ved 300 mg/75 mg regimet hos de andre grupper af CYP2C19metabolisers.
English: Clopidogrel Apotex contains clopidogrel and belongs to a group of medicines called antiplatelet medicinal products.
Danish: Clopidogrel Apotex indeholder clopidogrel og tilhører en lægemiddelgruppe, der kaldes blodforyndende medicin.
English: In patients who were enrolled in the trial on the sole basis of a recent myocardial infarction, clopidogrel was numerically inferior, but not statistically different from ASA (RRR = -4.0%; CI: -22.5 to 11.7 [p=0.639]).
Danish: Hos de patienter, som alene indgik i studiet på grund af et nyligt myokardieinfarkt, lå clopidogrel numerisk lavere, men ikke statistisk forskelligt fra ASA (RRR= 4,0 %, CI: -22,5 til 11,7 [p=0,639]).
English: The clinical benefit provided by the more potent P2Y12 inhibitors, ticagrelor and prasugrel, in their pivotal studies is related to a significant reduction in recurrent ischaemic events (including acute and subacute stent thrombosis (ST), myocardial infarction (MI), and urgent revascularization).
Danish: Den kliniske fordel, der kommer fra de mere potente P2Y12-hæmmere, ticagrelor og prasugrel, i deres afgørende studier er relateret til en signifikant reduktion i recidiverende iskæmiske hændelser (inklusive akut og subakut strenttrombose (ST), myokardieinfarkt (MI) og umiddelbar revakularisering).
English: Pharmathen S.A. 6, Dervenakion 15351 Pallini Attiki Greece
Danish: Pharmathen S.A. 6, Dervenakion str. 15351 Pallini Attiki Grækenland
English: If you have experienced severe chest pain (unstable angina or heart attack), your doctor may give you 300 mg of Clopidogrel Apotex (4 tablets of 75 mg) once at the start of treatment.
Danish: Hvis du har haft alvorlige brystsmerter (hjertekrampe (ustabil angina pectoris) eller hjertetilfælde), vil din læge måske indlede behandlingen med at give dig 300 mg Clopidogrel Apotex på en gang(4 tabletter af 75 mg).
English: As a precautionary measure, breast-feeding should not be continued during treatment with Clopidogrel Apotex.
Danish: Som forholdsregel bør amning ophøre under behandling med Clopidogrel Apotex.
English: Clopidogrel Apotex is taken by adults to prevent blood clots (thrombi) forming in hardened blood vessels (arteries), a process known as atherothrombosis, which can lead to atherothrombotic events (such as stroke, heart attack, or death).
Danish: Clopidogrel Apotex tages af voksne for at forebygge dannelse af blodpropper (trombi) i blodårer (arterier), som er blevet stive ved en proces kaldet aterotrombose, hvilket kan føre til f.eks. apopleksi, hjerteanfald og død (aterotrombotiske hændelser).
English: A crossover study in 40 healthy subjects, 10 each in the four CYP2C19 metaboliser groups (ultrarapid, extensive, intermediate and poor), evaluated pharmacokinetic and antiplatelet responses using 300 mg followed by 75 mg/day and 600 mg followed by 150 mg/day, each for a total of 5 days (steady state).
Danish: Et cross-over studie med 40 raske forsøgspersoner, 10 i hver af de fire CYP2C19-metaboliser-grupper (ultrahurtig, extensive, intermediate eller poor), evaluerede farmakokinetisk og trombocythæmmende respons ved dosering af 300 mg efterfulgt af 75 mg/dag og 600 mg efterfulgt af 150 mg/dag, hver i alt5 dage (steady state).
English: Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole.
Danish: Der er observeret mindre udtalte reduktioner af eksponeringen for den aktive metabolit med pantoprazol ellerog lansoprazol.
English: If you forget for more than 12 hours, simply take the next single dose at the usual time.
Danish: Hvis du glemmer at tage en tablet i over 12 timer, skal du blot tage den næste enkeltdosis tilsædvanlig tid.
English: Bleeding may occur as bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine.
Danish: Blødning kan forekomme i form af blødninger fra mave eller tarm, blå mærker, hæmatom (usædvanlig blødningeller blodudtrædning i underhuden), næseblod, blod i urinen.
English: The guided de-escalation did not result in an increased combined risk of ischemic events (2.5% in the deescalation group vs 3.2% in the control group; p non-inferiority=0.0115), nor in the key secondary endpoint of BARC bleeding ≥2 ((5%) in the de-escalation group versus 6% in the control group (p=0.23)).
Danish: Den guidede de-eskalering resulterede ikke i en øget kombineret risiko for iskæmiske hændelser (2,5 % i de-ekaleringsgruppen vs 3,2 % i kontrolgruppen; p noninferioritet=0,0115), ej heller i det nøglemæssige sekundære endepunkt for BARC-blødning ≥2 ((5 %) i de-eskaleringsgruppen versus 6 % i kontrolgruppen (p=0,23)).
English: If you have experienced severe chest pain (unstable angina or heart attack), you may be prescribed Clopidogrel Apotex in combination with acetylsalicylic acid, a substance present in many medicines used to relieve pain and lower fever.
Danish: Hvis du har haft alvorlige smerter i brystet (hjertekrampe (ustabil angina pectoris) eller hjerteanfald), kan din læge ordinere Clopidogrel Apotex i kombination med acetylsalicylsyre, som er et stof, der indgår i mange typer medicin til smertelindring og febersænkning.
English: You have experienced a severe type of chest pain known as ‘unstable angina' or ‘myocardial infarction' (heart attack).
Danish: Du har haft en alvorlig form for smerter i brystet, som kaldes hjertekrampe (ustabil angina pectoris) eller hjerteanfald (myokardieinfarkt).
English: TROPICAL-ACS (Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes)
Danish: TROPICAL ACS (Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes - Testning af reagering på trombocyt-hæmning ved kronisk antitrombocytbehandling for akut koronarsyndrom)
English: You have an irregular heartbeat, a condition called ‘atrial fibrillation', and you cannot take medicines known as ‘oral anticoagulants' (vitamin K antagonists) which prevent new clots from forming and prevent existing clots from growing.
Danish: Du har uregelmæssig hjerterytme (en sygdom kaldet ”atrieflimren”) og ikke må tage medicin kendt som orale antikoagulantia (vitamin K-antagonister), der kan forebygge dannelsen af nye blodpropper og forhindre eksisterende blodpropper i at vokse.
English: For patients over 75 years of age clopidogrel should be initiated without a loading dose.
Danish: Patienter, der er ældre end75 år, bør ikke indlede behandlingen med clopidogrel med en stabiliseringsdosis.
English: EU/1/09/568/001-018
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/09/568/001-018
English: Omeprazole 80 mg once daily administered either at the same time as clopidogrel or with 12 hours between the administrations of the two drugs decreased the exposure of the active metabolite by 45% (loading dose) and 40% (maintenance dose).
Danish: 80 mg omeprazol en gang daglig administreret enten samtidigt med clopidogrel eller med 12 timers mellemrum nedsatte eksponeringen for den aktive metabolit med 45 % (ved initial stabilisermætningsdosis) og 40 % (vedligeholdelsesdosis).
English: For more than 12 hours: patients should take the next dose at the regular scheduled time and should not double the dose.
Danish: Mere end 12 timer efter planlagt administration: patienten skal tage næste dosis som planlagt og ikke tage dobbelt dosis.
English: If you become pregnant while taking Clopidogrel Apotex, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant.
Danish: Hvis du bliver gravid, mens du tager Clopidogrel Apotex, skal du omgående kontakte din læge, da det frarådes at tage Clopidogrel Apotex under graviditet.
English: CYP2C19 is involved in the formation of both the active metabolite and the 2-oxo-clopidogrel intermediate metabolite.
Danish: CYP2C19 er involveret i dannelsen af såvel den aktive metabolit, som mellemstadiemetabolitten 2- oxoclopidogrel.
English: Common side effects (may affect up to 1 in 10 people: Diarrhoea, abdominal pain, indigestion or heartburn.
Danish: Almindelige bivirkninger (kan påvirke op til 1 ud af 10 patienter): Diaré, mavesmerter, fordøjelsesbesvær eller halsbrand.
English: The use of clopidogrel in CURE was associated with a decrease in the need of thrombolytic therapy (RRR = 43.3%; CI: 24.3%, 57.5%) and GPIIb/IIIa inhibitors (RRR = 18.2%; CI: 6.5%, 28.3%).
Danish: I CURE var anvendelse af clopidogrel forbundet med et aftagende behov for behandling med trombolytika (RRR = 43,3 %, CI: 24,3 %, 57,5 %) og GPIIb/IIIa-hæmmere (RRR = 18,2 %, CI: 6,5
English: The Cmax of the active metabolite is twice as high following a single 300-mg clopidogrel loading dose as it is after four days of 75-mg maintenance dose.
Danish: Cmax for den aktive metabolit er dobbelt så høj efter en initial mætningsdosis på 300 mg clopidogrel, som den er efter fire dage med 75 mg vedligeholdelsesdosis.
English: In patients with acute ST-segment elevation MI, safety and efficacy of clopidogrel have been evaluated in 2 randomised, placebo-controlled, double-blind studies, CLARITY and COMMIT.
Danish: Hos patienter med akut myokardieinfarkt (MI) med ST-segmentelevation blev sikkerheden ved og effekten af clopidrogrel vurderet i 2 randomiserede, placebo-kontrollerede, dobbeltblindede undersøgelser kaldet CLARITY og COMMIT.
English: The CAPRIE study included 19,185 patients with atherothrombosis as manifested by recent myocardial infarction (<35 days), recent ischaemic stroke (between 7 days and 6 months) or established peripheral arterial disease (PAD).
Danish: CAPRIE-studiet omfattede 19.185 patienter med aterotrombose manifesteret ved nyligt myokardieinfarkt (<35 dage), nyligt iskæmisk slagtilfælde (mellem 7 dage og 6 måneder) eller påviste perifere kredsløbsforstyrrelser (PAD).
English: Thus, beyond 3 months of treatment, the benefit observed in the clopidogrel + ASA group was not further increased, whereas the risk of haemorrhage persisted (see section 4.4).
Danish: Efter 3 måneders behandling blev den observerede fordel således ikke yderligere forbedret iclopidogrel+ASA-gruppen, hvorimod der stadig forelå en blødningsrisiko (se pkt.
English: Prevention of atherothrombotic and thromboembolic events in atrial fibrillation
Danish: Forebyggelse af aterotrombotiske og tromboemboliske hændelser ved atrieflimren
English: Thrombotic thrombocytopenic purpura (TTP) (see section 4.4), aplastic anaemia, pancytopenia, agranulocytosis, severe thrombocytopenia, acquired haemophilia A, granulocytopenia, anaemia
Danish: Trombotisk trombocytopenisk purpura (TTP) (se afsnit 4.4), aplastisk anæmi, pancytopeni, agranulocytose, alvorlig trombocytopeni, erhvervet hæmofili A, granulocytopeni, anæmi