FrancophonIA/ELRC3.0 huggingface dataset:
English: Common Blood alkaline phosphatase increased Uncommon Blood albumin increased, protein total increased, blood albumin decreased, pH urine increased
Danish: Forhøjet albumin i blodet, forhøjet total protein, nedsat albumin i blodet, forhøjet pH i urinen
English: Paediatric population (aged 1 to 17 years) The safety and efficacy of eltrombopag in paediatric patients have been investigated in two studies.
Danish: Pædiatrisk population (i alderen 1 til 17 år) Eltrombopags sikkerhed og effekt hos pædiatriske patienter er blevet undersøgt i to studier.
English: • sudden shortness of breath, especially together with sharp pain in the chest or rapid breathing
Danish: • pludselig åndenød, specielt ledsaget af en skarp smerte i brystet eller hurtig vejrtrækning
English: INSTRUCTIONS FOR USE
Danish: Instruktioner for anvendelsen
English: Five of the 6 patients treated with eltrombopag experienced the TEE at a platelet count >200,000/µl.
Danish: Fem ud af de 6 patienter, der blev behandlet med eltrombopag, oplevede TEE ved et trombocyttal > 200.000 pr. µl.
English: • decreased number of red blood cells (anaemia) cause by excessive destruction of red blood cells
Danish: • nedsat antal røde blodlegemer (anæmi) der skyldes øget nedbrydning af røde blodlegemer
English: Patients with bleeding (WHO Grades 1-4) at any time during 6 months, n (%)
Danish: Patienter med blødning (WHO niveau 1-4) på et tidspunkt i løbet af de 6 måneder, n (%)
English: p-valuea a Logistic regression model adjusted for randomisation stratification variables
Danish: Logistisk regressionsmodel justeret for stratificeringsvariable i randomiseringen
English: • antacid medicines to treat indigestion, heartburn or stomach ulcers (see also ‘When to take it' in section 3)
Danish: • syreneutraliserende lægemidler til behandling af fordøjelsesproblemer, halsbrand og mavesår (se også ‘Hvornår skal du tage Revolade' under punkt 3)
English: • yellowing of the whites of the eyes or skin (jaundice)
Danish: • gulfarvning af det hvide i øjnene eller af huden (gulsot)
English: 30 sachets and 1 mixing bottle + 30 single-use oral syringes
Danish: 30 breve og 1 blandeflaske + 30 orale doseringssprøjter til engangsbrug
English: Administration of eltrombopag concomitantly with antacids and other products containing polyvalent cations such as dairy products and mineral supplements significantly reduces eltrombopag exposure (see section 4.2).
Danish: Administration af eltrombopag samtidig med antacida og andre produkter med polyvalente kationer, som f.eks. mejeriprodukter og mineraltilskud, nedsætter i signifikant grad optagelsen af eltrombopag (se pkt.
English: If you are taking interferon-based treatments together with Revolade you will be monitored for any signs of bleeding in your stomach or intestine after you stop taking Revolade.
Danish: Undersøgelser for blødning i fordøjelsessystemet Hvis du tager Revolade sammen med interferonbehandling, vil du blive undersøgt for tegn på blødninger i din mave eller tarm, når du stopper med at tage Revolade.
English: Method of administration (see section 6.6)
Danish: Administration (se pkt.
English: You will need regular tests
Danish: Regelmæssige prøver
English: Administration of a single dose of eltrombopag 75 mg with a polyvalent cation-containing antacid (1524 mg aluminium hydroxide and 1425 mg magnesium carbonate) decreased plasma eltrombopag AUC0- by 70% (90% CI: 64%, 76%) and Cmax by 70% (90% CI: 62%, 76%).
Danish: Administration af en enkelt dosis eltrombopag 75 mg med et polyvalent kation-holdigt antacida (1524 mg aluminiumhydroxid og 1425 mg magnesiumcarbonat) nedsatte plasmaeltrombopag-AUC0- med 70 % (90 % CI: 64 %, 76 %) og Cmax med 70 % (90 % CI: 62 %, 76 %).
English: • dizziness, problems with attention and memory, change in mood
Danish: • svimmelhed, problemer med at koncentrere sig eller huske, humørændringer
English: • fever, headache
Danish: • feber, hovedpine
English: The most important serious adverse reactions were hepatotoxicity and thrombotic/thromboembolic events.
Danish: De vigtigste alvorlige bivirkninger var hepatotoksicitet og trombotiske/tromboemboliske bivirkninger.
English: Clinical haematology and liver tests should be monitored regularly throughout therapy with eltrombopag and the dose regimen of eltrombopag modified based on platelet counts as outlined in Table 1.
Danish: Klinisk hæmatologi og levertal skal monitoreres regelmæssigt i hele behandlingsperioden med eltrombopag, og dosis skal ændres ud fra trombocyttallet, som vist i tabel 1.
English: A study in 40 healthy volunteers showed that the co-administration of a single 100 mg dose of eltrombopag with repeat dose lopinavir/ritonavir 400/100 mg twice daily resulted in a reduction in eltrombopag plasma AUCinf by 17% (90% CI: 6.6%, 26.6%).
Danish: Et studie med 40 raske frivillige viste, at samtidig administration af en enkelt 100 mg dosis af eltrombopag og en gentagen dosis lopinavir/ritonavir 400/100 mg to gange daglig, resulterede i en reduktion af plasma-eltrombopag-AUCinf med 17 % (90 % CI: 6,6 %, 26,6 %).
English: • decreased number of red blood cells (anaemia)
Danish: • nedsat antal røde blodlegemer (anæmi)
English: Take Revolade
Danish: Tag Revolade
English: Contents of the pack and other information Instructions for use
Danish: Pakningsstørrelser og yderligere oplysninger Brugsanvisning
English: Overall SVR
Danish: Samlet SVR
English: The influence of Asian ethnicity (such as Chinese, Japanese, Taiwanese, Korean, and Thai) on the pharmacokinetics of eltrombopag was evaluated using a population pharmacokinetic analysis in 635 patients with HCV (145 Asians and 69 South Asians).
Danish: Indflydelsen af asiatisk etnicitet (f.eks. kinesisk, japansk, taiwanesisk, koreansk og thailandsk) på eltrombopags farmakokinetik blev vurderet ved hjælp af en farmakokinetisk populationsanalyse med 635 patienter med HCV (145 asiater og 69 sydasiater).
English: In a small number of ITP patients, eltrombopag treatment was discontinued due to bone marrow reticulin (see section 4.4).
Danish: Hos et lille antal ITP-patienter blev behandlingen med eltrombopag seponeret pga. knoglemarvsretikulin (se pkt.
English: • decreased level of blood proteins
Danish: • nedsat niveau af proteiner i blodet
English: AUC(0-) (µg.hr/ml)
Danish: AUC(0-) (µg.t/ml)
English: Other liver problems (bile not flowing properly) are uncommon and may affect up to 1 in 100 people.
Danish: Andre leverproblemer (påvirkning af tilstrømning af galde) er ikke almindeligt og kan forekomme hos op til 1 ud af 100 personer.
English: Each pack contains 30 sachets, one 40 ml reusable mixing bottle with lid and cap, and 30 single-use oral dosing syringes.
Danish: Hver pakning indeholder 30 breve, en genanvendelig 40 ml blandeflaske med låg og hætte samt 30 doseringssprøjter til engangsbrug til oral dosering.
English: No dose adjustment is necessary in patients with renal impairment.
Danish: Det er ikke nødvendigt med dosisændringer til patienter med nedsat nyrefunktion.
English: • 75 mg dose - 3 sachets
Danish: • 75 mg dosis - 3 breve
English: • liver problems
Danish: • leverproblemer
English: Following administration of a single 50 mg dose, the AUC0- of eltrombopag was 32% to 36% lower in patients with mild to moderate renal impairment, and 60% lower in patients with severe renal impairment compared with healthy volunteers.
Danish: Efter administration af en enkelt dosis på 50 mg var AUC0- for eltrombopag 32-36 % lavere hos patienter med let til moderat nedsat nyrefunktion, og 60 % lavere hos patienter med svært nedsat nyrefunktion, end hos raske frivillige.
English: The following side effects have been reported to be associated with treatment with Revolade in combination with peginterferon and ribavirin in patients with HCV:
Danish: Følgende bivirkninger er blevet indberettet til at være forbundet med behandling af Revolade kombination med peginterferon og ribavirin hos patienter med hepatitic C (HCV):
English: The profile of adverse reactions was comparable to that seen in adults with some additional adverse reactions, marked ♦ in the table below.
Danish: Bivirkningsprofilen var sammenlignelig med profilen set for voksne med nogle yderligere bivirkninger.
English: The co-administration of 200 mg ciclosporin decreased the Cmax and the AUCinf of eltrombopag by 25% and 18%, respectively.
Danish: Samtidig administration af 200 mg ciclosporin reducerede eltrombopags Cmax og AUCinf med henholdsvis 25 % og 18 %.
English: The platelet count will be monitored, and your doctor will discuss appropriate precautions with you.
Danish: Blodpladetallet vil blive overvåget, hvis du stopper med at tage Revolade, og lægen vil diskutere passende forholdsregler med dig.
English: Revolade 12.5 mg, 25 mg, 50 mg and 75 mg film-coated tablets:
Danish: Revolade 12,5 mg, 25 mg, 50 mg og 75 mg filmovertrukne tabletter
English: In the pre- and post-natal development study in rats, there were no undesirable effects on pregnancy, parturition or lactation of F0 female rats at maternally non-toxic doses (10 and 20 mg/kg/day) and no effects on the growth, development, neurobehavioural or reproductive function of the offspring (F1).
Danish: I det præ- og postnatale udviklingsstudie hos rotter sås ingen uønskede påvirkninger af graviditeten, fødslen eller diegivningen hos F0-hunrotter ved en maternel, ikketoksiske doser (10 og 20 mg/kg/dag).
English: In a placebo-controlled study (n=288, Safety population), following 2 weeks' treatment in preparation for invasive procedures, 6 of 143 (4%) adult patients with chronic liver disease receiving eltrombopag experienced 7 TEEs of the portal venous system and 2 of 145 (1%) patients in the placebo group experienced 3 TEEs.
Danish: I et placebo-kontrolleret studie (n = 288, sikkerhedspopulation) efter to ugers behandling forud for invasive indgreb oplevede 6 ud af 143 (4 %) voksne patienter med kronisk leversygdom, der fik eltrombopag, 7 TEEs i det portale venesystem, og 2 ud af 145 (1 %) patienter i placebogruppen oplevede 3 TEEs.
English: Excessive platelet count responses or important liver test abnormalities also necessitate discontinuation.
Danish: Udtalt trombocyttalrespons eller afgørende unormale levertal kræver også seponering.
English: Eltrombopag dose adjustment is permitted during the course of the treatment based on the patient's platelet count (see section 4.2).
Danish: Det er tilladt at justere eltrombopagdosis under behandlingsforløbet baseret på patientens trombocyttal (se pkt.
English: Common Hyperglycaemia, abnormal loss of weight
Danish: Almindelig Hyperglykæmi, abnormt vægttab
English: ♦ For patients taking 25 mg eltrombopag once daily, consideration should be given to dosing at 12.5 mg once daily or alternatively a dose of 25 mg once every other day.
Danish: ♦ For patienter, der tager 25 mg eltrombopag én gang daglig, bør det overvejes at dosere med 12,5 mg én gang daglig eller alternativt en dosis på 25 mg en gang hver anden dag.
English: • painful swollen joints caused by uric acid (gout)
Danish: • smertefulde, hævede led pga. urinsyre (urinsyregigt)
English: • Revolade is used to treat a bleeding disorder called immune (primary) thrombocytopenia (ITP) in patients aged 1 year and above who have already taken other medicines (corticosteroids or immunoglobulins), which have not worked.
Danish: • Revolade bruges til at behandle en blodsygdom kaldet immun (primær) trombocytopeni (ITP) hos patienter i alderen 1 år og derover, og som tidligere har fået behandling med andet medicin (kortikosteroider eller immunglobuliner) uden effekt.
English: It is recommended that, if treatment with eltrombopag is discontinued, ITP treatment be restarted according to current treatment guidelines.
Danish: Hvis behandlingen med eltrombopag seponeres, anbefales det, at patienten igen behandles med ITPmedicin ud fra de gældende retningslinjer.
English: Uncommon Tachycardia, acute myocardial infarction, cardiovascular disorder, cyanosis, sinus tachycardia, electrocardiogram QT prolonged
Danish: Takykardi, akut myokardieinfarkt, kardiovaskulære sygdomme, cyanose, sinus takykardi, QT-forlængelse ved EKG
English: HCV protease inhibitors
Danish: HCV-proteasehæmmere
English: Overall, a significantly greater proportion of eltrombopag patients (40%) compared with placebo patients (3%) achieved the primary endpoint (Odds Ratio: 18.0 [95% CI: 2.3, 140.9] p <0.001) which was similar across the three age cohorts (Table 6).
Danish: Samlet set opnåede en signifikant højere andel af eltrombopagpatienterne (40 %) sammenlignet med placebopatienterne (3 %) det primære endepunkt (Odds Ratio: 18,0 [95 % CI: 2,3; 140,9] p < 0,001), og resultaterne var omtrent ens på tværs af de tre alderskohorter (tabel 6).
English: Eltrombopag dose may need to be increased based on these platelet counts.
Danish: Det kan være nødvendigt at øge eltrombopagdosis på baggrund af disse trombocyttal.
English: They are supplied in aluminum blisters in a carton containing 14 or 28 film-coated tablets and multipacks containg 84 (3 packs of 28) film-coated tablets).
Danish: Revolade leveres i aluminiumsblisterpakninger i en æske indeholdende 14 eller 28 filmovertrukne tabletter og multipakninger indeholdende 84 (3 pakninger af 28) filmovertrukne tabletter.
English: A loss of response or failure to maintain a platelet response with eltrombopag treatment within the recommended dosing range should prompt a search for causative factors, including an increased bone marrow reticulin.
Danish: Ved problemer med manglende respons eller opretholdelse af trombocytresponset ved behandling med eltrombopag i det anbefalede dosisinterval, skal der søges efter årsagen til dette inklusive øget knoglemarvsretikulin.
English: Co-administration of a single dose of eltrombopag 200 mg with telaprevir 750 mg every 8 hours did not alter plasma telaprevir exposure.
Danish: Samtidig administration af en enkelt dosis eltrombopag på 200 mg og telaprevir 750 mg hver 8. time ændrede ikke plasmaniveauerne af telaprevir.
English: If you are of Asian origin (Chinese, Japanese, Taiwanese, Thai or Korean) you will start on the same 25 mg dose.
Danish: Hvis du er af asiatisk oprindelse (kinesisk, japansk, taiwanesisk, thailandsk eller koreansk) vil du begynde med den samme dosis på 25 mg.
English: The administration of eltrombopag tablet or powder for oral suspension formulations with a highcalcium meal (e.g. a meal that included dairy products) significantly reduced plasma eltrombopag AUC0-∞ and Cmax.
Danish: Administration af eltrombopag som tabletter eller pulver til oral suspension sammen med et calciumrigt måltid (f.x et måltid, der indeholdt mejeriprodukter) reducerede eltrombopags AUC0-∞ og Cmax i plasma signifikant.
English: In vitro studies demonstrate that eltrombopag is an inhibitor of the OATP1B1 transporter and an inhibitor of the BCRP transporter and eltrombopag increased exposure of the OATP1B1 and BCRP substrate rosuvastatin in a clinical drug interaction study (see section 4.5).
Danish: In vitro-studier viser, at eltrombopag er en hæmmer af OATP1B1- og BCRP-transporteren, og i et klinisk lægemiddelinteraktionsstudie sås, at eltrombopag øger eksponeringen af OATP1B1- og BCRPsubstratet rosuvastatin (se pkt 4.5).
English: 30 sachets.
Danish: 30 breve.
English: The following side effects have been reported to be associated with treatment with Revolade in patients with severe aplastic anaemia (SAA):
Danish: Følgende bivirkninger er blevet indberettet til at være forbundet med behandling af Revolade hos patienter med svær aplastisk anæmi (SAA):
English: If you have questions or do not understand the Instructions For Use, talk to your doctor, nurse or pharmacist.
Danish: Hvis du har spørgsmål eller ikke forstår brugsanvisningen, skal du tale med lægen, sundhedspersonalet eller apotekspersonalet.
English: Dose adjustments are based upon the platelet count response.
Danish: Dosisjusteringer er baseret på trombocyttalresponset.
English: If you have any questions, or if you damage or lose any of the supplies in your kit, ask your doctor, nurse or pharmacist for advice
Danish: Hvis du har spørgsmål, eller hvis en eller flere af delene i dit sæt bliver væk eller går i stykker, skal du spørge lægen, sundhedspersonalet eller apotekspersonalet til råds
English: Following the administration of a single 50 mg dose, the AUC0- of eltrombopag was 41% higher in patients with mild hepatic impairment and 80% to 93% higher in patients with moderate to severe hepatic impairment compared with healthy volunteers.
Danish: Efter administration af en enkelt dosis på 50 mg var AUC0- for eltrombopag 41 % højere hos patienter med let nedsat leverfunktion, og 80-93 % højere hos patienter med moderat til svært nedsat leverfunktion, end hos raske frivillige.
English: • 50 mg dose - 2 sachets
Danish: • 50 mg dosis - 2 breve
English: Overall, total bilirubin ≥1.5 x ULN was reported in 76% and 50% of the eltrombopag and placebo groups, respectively.
Danish: Samlet blev der rapporteret et niveau af totalbilirubin på ≥ 1,5 x ULN hos henholdsvis 76 % i eltrombopag-gruppen og 50 % i placebogruppen.
English: Table 6 Sustained platelet response rates by age cohort in paediatric patients with chronic ITP
Danish: Tabel 6 Vedvarende trombocytresponsrater efter alderskohorte hos pædiatriske patienter med kronisk ITP
English: Plasma eltrombopag concentration-time data collected in 590 patients with HCV enrolled in phase III studies TPL103922/ENABLE 1 and TPL108390/ENABLE 2 were combined with data from patients with HCV enrolled in the phase II study TPL102357 and healthy adult patients in a population PK analysis.
Danish: Data for plasmakoncentrationen af eltrombopag over tid, indsamlet hos 590 patienter med HCV, som var inkluderet i fase III-studierne TPL103922/ENABLE 1 og TPL108390/ENABLE 2, blev kombineret med data fra patienter med HCV, som var inkluderet i fase II-studiet TPL102357, og raske voksne personer i en farmakokinetisk populationsanalyse.
English: Common Aspartate aminotransferase increased
Danish: Almindelig Forhøjet aspartataminotransferase
English: The safety of eltrombopag in severe aplastic anaemia was assessed in a single-arm, open-label study (N=43) in which 11 patients (26%) were treated for >6 months and 7 patients (16%) were treated for >1 year.
Danish: Eltrombopags sikkerhed ved svær aplastisk anæmi er vurderet i et åbent enkeltgruppestudie (n = 43), i hvilket 11 patienter (26 %) blev behandlet i > 6 måneder, og 7 patienter (16 %) blev behandlet i > 1 år.
English: The safety of eltrombopag in severe aplastic anaemia was assessed in a single-arm, open-label study (N=43) in which 11 patients (26%) were treated for >6 months and 7 patients (21%) were treated for >1 year.
Danish: Eltrombopags sikkerhed ved svær aplastisk anæmi er vurderet i et åbent enkeltgruppestudie (N = 43), i hvilket 11 patienter (26 %) blev behandlet i > 6 måneder, og 7 patienter (21%) blev behandlet i > 1 år.
English: Eltrombopag should be taken at least two hours before or four hours after any products such as antacids, dairy products or mineral supplements containing polyvalent cations to avoid significant reduction in eltrombopag absorption due to chelation (see sections 4.2 and 5.2).
Danish: Eltrombopag skal tages mindst to timer før eller fire timer efter produkter, såsom antacida, mejeriprodukter eller mineraltilskud, der indeholder polyvalente kationer, for at undgå en signifikant reducering af absorptionen af eltrombopag pga. chelering (se pkt.
English: The influence of age on eltrombopag pharmacokinetics was evaluated using population pharmacokinetics analysis in 28 healthy subjects, 673 patients with HCV, and 41 patients with chronic liver disease of other aetiology ranging from 19 to 74 years old.
Danish: Indflydelsen af alder på eltrombopags farmakokinetik blev vurderet vha. en farmakokinetisk populationsanalyse blandt 28 raske personer, 673 patienter med HCV og 41 patienter med kronisk leversygdom af anden ætiologi i alderen fra 19 til 74 år.
English: The influence of gender on the pharmacokinetics of eltrombopag was evaluated using a population pharmacokinetic analysis in 111 healthy adults (14 females) and 88 patients with ITP (57 females).
Danish: Indflydelsen af køn på eltrombopags farmakokinetik blev vurderet vha. en farmakokinetisk populationsanalyse blandt 111 raske voksne (14 kvinder) og 88 patienter med ITP (57 kvinder).
English: Patients were randomised 2:1 and received Revolade (n=44) or placebo (n=21), for up to 7 weeks.
Danish: Patienter blev randomiseret i forholdet 2:1 og fik Revolade (n = 44) eller placebo (n = 21) i op til 7 uger.
English: • feeling cold
Danish: • kuldefølelse
English: 30 single-use oral dosing syringes
Danish: 30 orale doseringssprøjter til engangsbrug
English: If you are of Asian origin (Chinese, Japanese, Taiwanese, Thai or Korean) you may need to start at a lower dose of 25 mg.
Danish: Hvis du er af asiatisk oprindelse (kinesisk, japansk, taiwanesisk, thailandsk eller koreansk) kan det være nødvendigt at begynde med en lavere dosis på 25 mg.
English: • 25 mg dose - 1 sachet
Danish: • 25 mg dosis - 1 brev
English: Eltrombopag should be initiated at a dose of 50 mg once daily.
Danish: Eltrombopag bør opstartes i en dosis på 50 mg én gang daglig.
English: This risk is increased if eltrombopag treatment is discontinued in the presence of anticoagulants or anti-platelet agents.
Danish: Risikoen øges, hvis eltrombopag-behandlingen seponeres, mens der stadig gives antikoagulantia eller trombocythæmmere.
English: The lower platelet count may increase the risk of bleeding or bruising.
Danish: Det lavere blodpladetal kan forøge din risikoen for blødning og blå mærker.
English: Administration of eltrombopag 75 mg once daily for 5 days with a single 10 mg dose of the OATP1B1 and BCRP substrate rosuvastatin to 39 healthy adult subjects increased plasma rosuvastatin Cmax 103% (90% confidence interval [CI]: 82%, 126%) and AUC0- 55% (90% CI: 42%, 69%).
Danish: Administration af eltrombopag 75 mg én gang daglig i 5 dage til 39 raske voksne, sammen med en enkelt 10 mg dosis af OATP1B1- og BCRP-substratet rosuvastatin, øgede plasma-rosuvastatin Cmax med 103 % (90 % konfidensinterval [CI]: 82-126 %) og AUC0- med 55 % (90 % CI: 42-69 %).
English: Reported adverse reactions included mild rash, transient bradycardia, ALT and AST elevation, and fatigue.
Danish: De rapporterede bivirkninger omfattede et mildt udslæt, forbigående bradykardi, ALAT- og ASAT-forhøjelser samt træthed.
English: Patients with these characteristics should be closely monitored for signs and symptoms of hepatic decompensation.
Danish: Patienter med disse karakteristika skal monitoreres tæt for tegn og symptomer på dekompenseret leversygdom.
English: b p-value a a Logistic regression model adjusted for randomisation stratification variables b 21 out of 63 (33%) patients treated with eltrombopag who were taking an ITP medicinal product at baseline permanently discontinued all baseline ITP medicinal products.
Danish: Logistisk regressionsmodel justeret for stratificeringsvariable i randomiseringen b 21 ud af 63 patienter (33 %), der blev behandlet med eltrombopag, og som tog et ITPlægemiddel ved udgangsniveauet, stoppede alle udgangsniveau-ITP-lægemidler permanent.
English: • increase of liver enzymes (aspartate aminotransferase (AST))
Danish: • forhøjede leverenzymer (aspartataminotransferease (ASAT))
English: A daily dose of 75 mg must not be exceeded.
Danish: Den daglige dosis på maksimalt 75 mg i døgnet må ikke overskrides.
English: Common Chromaturia
Danish: Almindelig Kromaturi
English: • darkening of the skin
Danish: • mørkfarvning af huden
English: The dose of eltrombopag should be adjusted in 25 mg increments every 2 weeks as necessary to achieve the target platelet count required to initiate antiviral therapy.
Danish: Dosis af eltrombopag justeres med 25 mg hver 2. uge, indtil det tilsigtede trombocyttal, der er påkrævet til at indlede antiviral behandling, er opnået.
English: Eltrombopag treatment should be terminated when antiviral therapy is discontinued unless otherwise justified.
Danish: Behandlingen med eltrombopag bør afsluttes, når den antivirale behandling seponeres, medmindre andet taler imod dette.
English: • Insert the tip of the syringe into the hole in the lid of the mixing bottle.
Danish: • Sæt sprøjtens spids i hullet i blandeflaskens låg.