FrancophonIA/ELRC3.0 huggingface dataset:
English: Only a small minority of patients developed duodenal ulcers
Slovenian: Le pri maloštevilnih bolnikih se je razvila razjeda dvanajstnika.
English: Eradication of H. pylori has been shown to be a definitive cure for duodenum ulcer and most gastric ulcers.
Slovenian: Eradikacija bakterije H. pylori se je izkazala kot metoda za dokončno ozdravitev razjed dvanajstnika in večine razjed želodca.
English: The inhibition is dosedependent and reversible, and the effect applies to both basal and stimulated secretion of gastric acid.
Slovenian: Zaviranje je odvisno od odmerka in je reverzibilno, učinkuje pa na bazalno in tudi stimulirano izločanje želodčne kisline.
English: <Read all of this leaflet carefully because it contains important information for you.
Slovenian: <To navodilo vsebuje pomembne informacije, zato ga pozorno preberite.>
English: Agopton is indicated for use in: - Treatment of heartburn and acid regurgitation
Slovenian: Zdravilo Agopton je indicirano za uporabo pri: - zdravljenju zgage in vzdigovanja kisline
English: For the complete wording of section 4.5 please see attched SPC.
Slovenian: Celotno besedilo poglavja 4.5 najdete v priloženem SPC.
English: Decreased gastric acidity due to lansoprazole might be expected to increase gastric counts of bacteria normally present in the gastrointestinal tract.
Slovenian: Zmanjšana kislost v želodcu zaradi lansoprazola lahko poveča število bakterij, ki so normalno prisotne v prebavilih.
English: There is no evidence of accumulation following multiple doses in healthy subjects.
Slovenian: Po večkratnih odmerkih pri zdravih prostovoljcih ni dokazov o kopičenju.
English: A single oral dose of lansoprazole inhibits pentagastrin-stimulated gastric acid secretion by about 80%.
Slovenian: Enkratni 30-miligramski peroralni odmerek lansoprazola zavre izločanje želodčne kisline, ki ga spodbuja pentagastrin, za približno 80 %.
English: Administration of lansoprazole may result in sub-therapeutic concentrations of ketoconazole and itraconazole and the combination should be avoided.
Slovenian: Odmerjanje lansoprazola lahko zmanjša koncentracijo ketokonazola in itrakonazola pod terapevtsko raven, zato se je treba kombinaciji teh zdravil izogibati.
English: Do not take Agopton: - if you are allergic (hypersensitive) to lansoprazole or any of the other ingredients of Agopton - if you are taking a medicine containing the active substance atazanavir (used in the treatment of
Slovenian: KAJ MORATE VEDETI, PREDEN BOSTE VZELI ZDRAVILO AGOPTON Ne jemljite zdravila Agopton: - če ste preobčutljivi za (alergični na) lansoprazol ali katero koli sestavino zdravila Agopton; - če jemljete zdravilo, ki vsebuje zdravilno učinkovino atazanavir (uporablja se pri zdravljenju okužbe z virusom HIV).
English: You should report any new and exceptional symptoms and circumstances whenever you see your doctor.
Slovenian: Kadar koli ga obiščete, ga morate obvestiti o kakršnih koli novih ali izjemnih simptomih ali okoliščinah.
English: Fluvoxamine:
Slovenian: Fluvoksamin:
English: Do not use Agopton after the expiry date which is stated on the blister and carton.
Slovenian: Zdravila Agopton ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na pretisnem omotu in škatli.
English: If this happens skip the missed dose and take the remaining capsules as normal.
Slovenian: Če se to zgodi, izpustite pozabljeni odmerek in preostale kapsule vzemite, kot bi jih sicer.
English: Add 30 ml (two tablespoons) of tap water to a glass.
Slovenian: V kozarec dajte 30 ml (dve žlici) vode iz pipe.
English: <As Agopton contains lactose, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.>
Slovenian: <Zdravilo Agopton vsebuje laktozo, zato bolniki z redko dedno intoleranco za galaktozo, laponsko obliko zmanjšane aktivnosti laktaze ali malabsorpcijo glukoze/galaktoze ne smejo jemati tega zdravila.>
English: The tablet rapidly disperses in the mouth, releasing gastro-resistant microgranules which are swallowed with the patient's saliva.
Slovenian: Tableta se v ustih hitro raztopi, pri čemer se sprostijo gastrorezistentna zrnca, ki jih bolnik pogoltne s slino.
English: Studies have shown that oro-dispersible tablets dispersed in a small amount of water and given via syringe directly into the mouth or administered via naso-gastric tube result in equivalent AUC compared to the usual mode of admnisistration.
Slovenian: Študije so pokazale, da je vrednost AUC pri uporabi orodisperzibilnih tablet, raztopljenih v malo vode in danih z brizgo neposredno v usta ali po nazogastrični cevki, enaka kot pri običajnem načinu uporabe.
English: You can also swallow the tablet whole with a glass of water.
Slovenian: Tablete lahko tudi pogoltnete cele s kozarcem vode.
English: The usually recommended dose in patients with normal hepatic function is 30 mg q.d.
Slovenian: Običajno priporočen odmerek za bolnike z normalnim delovanjem jeter znaša 30 mg enkrat dnevno.
English: What Agopton looks like and contents of the pack
Slovenian: Izgled zdravila Agopton in vsebina pakiranja
English: If symptoms persist you should report to your doctor.
Slovenian: Če so simptomi še vedno enaki, povejte zdravniku.
English: The second study examined the use of lansoprazole in the maintenance of healed ulcer (prevention of relapse) of duodenal or gastric ulcer disease resistant H2 blockers.
Slovenian: Druga raziskava je preučevala uporabo lansoprazola pri vzdrževanju zaceljene razjede (preprečevanju ponovitve) pri ulkusni bolezni dvanajstnika ali želodca, rezistentni na antagoniste receptorjev H2.
English: When reconstituted in water Agopton is a pink suspension with a strawberry flavour.
Slovenian: V vodi rekonstituirano zdravilo Agopton tvori rožnato suspenzijo z okusom jagode.
English: The objective of one study was to compare the efficacy and safety of lansoprazole 15mg qd with placebo in preventing the recurrence of duodenal ulceration in patients with a history of recently healed duodenal ulcer.
Slovenian: Cilj ene od raziskav je bila primerjava učinkovitosti in varnosti lansoprazola 15 mg enkrat dnevno napram placebu pri preprečevanju ponovitve razjed dvanajstnika pri bolnikih z nedavno zaceljeno razjedo dvanajstnika.
English: Nausea, diarrhoea, stomach ache, constipation, vomiting, flatulence, dry mouth or throat
Slovenian: Bolezni prebavil Navzea, driska, bolečine v trebuhu, zaprtje, bruhanje, flatulenca, suha usta ali grlo
English: How to take Agopton 4.
Slovenian: Kako jemati zdravilo Agopton 4.
English: The plasma levels of digoxin should therefore be monitored and the dose of digoxin adjusted if necessary when initiating and ending lansoprazole treatment.
Slovenian: Zato je treba ob začetku in koncu zdravljenja z lansoprazolom nadzorovati ravni digoksina v plazmi in odmerek digoksina po potrebi prilagoditi.
English: Medicinal products transported by P-glycoprotein Lansoprazole has been observed to inhibit the transport protein, P-glycoprotein (P-gp) in vitro.
Slovenian: Opazili so, da lansoprazol in vitro zavira transportno beljakovino P-glikoprotein (P-gp).
English: The clinical trials showed consistently gastric acid suppression and relief of symptoms in children and adolescents when treated with lansoprazole.
Slovenian: Klinične raziskave so pri zdravljenju z lansoprazolom pokazale konsistentno zaviranje izločanja želodčne kisline in lajšanje simptomov pri otrocih in mladostnikih.
English: Agopton contains aspartame.
Slovenian: Zdravilo Agopton vsebuje aspartam.
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients [To be completed nationally]
Slovenian: FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi [Izpolni država članica.]
English: Interstitial nephritis
Slovenian: Intersticijski nefritis
English: Symptoms of a hypersensitivity reaction may include fever, rash, swelling and sometimes a fall in blood pressure - inflammation of your mouth (stomatitis) - colitis (bowel inflammation) - changes in test values such as sodium, cholesterol and triglyceride levels - very severe skin reactions with reddening, blistering, severe inflammation and skin loss.
Slovenian: Med simptomi preobčutljivosti so lahko zvišana telesna temperatura, izpuščaj, otekanje in včasih znižanje krvnega tlaka; - vnetje ust (stomatitis); - kolitis (vnetje črevesa); - spremembe vrednosti preiskav, kot so ravni natrija, holesterola in trigliceridov; - zelo hude kožne reakcije z rdečico, mehurji, hudimi vnetji in izgubo kože.
English: The exposure of lansoprazole is doubled in patients with mild hepatic impairment and much more increased in patients with moderate and severe hepatic impairment.
Slovenian: Pri bolnikih z blago jetrno okvaro je izpostavljenost lansoprazolu podvojena, pri bolnikih z zmerno in hudo jetrno okvaro pa še večja.
English: The recommended dose is 15 mg or 30 mg daily.
Slovenian: Priporočeni odmerek je 15 ali 30 mg na dan.
English: <As Agopton contains sucrose, patients with rare hereditary problems of fructose intolerance, glucosegalactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.>
Slovenian: <Zdravilo Agopton vsebuje saharozo, zato bolniki z redko dedno intoleranco za fruktozo, malabsorpcijo glukoze/galaktoze ali pomanjkanjem saharoza-izomaltaze ne smejo jemati tega zdravila.>
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION [To be completed nationally]
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET [Izpolni država članica.]
English: Do not take a double dose to make up for a forgotten oro-dispersible tablet.
Slovenian: Ne vzemite dvojnega odmerka, če ste pozabili vzeti prejšnjo orodisperzibilno tableto.
English: Agopton contains mannitol, which may have a mild laxative effect.
Slovenian: Zdravilo Agopton vsebuje manitol, ki je lahko blago odvajalo.
English: The CHMP requested, the MAH to submit a full review of the paediatric data and to make an adequate proposal for the treatment of children in the relevant sections of the SPC The applicant answered the question on paediatric data with the filing of a complete paediatric data package.
Slovenian: CHMP je od imetnika dovoljenja za promet z zdravilom zahteval, da predloži popoln pregled pediatričnih podatkov ter izdela ustrezen predlog za zdravljenje otrok v zadevnih poglavjih SPC.
English: The active ingredient in Agopton is lansoprazole, which is a proton pump inhibitor.
Slovenian: Zdravilna učinkovina v zdravilu Agopton je lansoprazol, ki je zaviralec protonske črpalke.
English: If you forget to take Agopton
Slovenian: Če ste pozabili vzeti zdravilo Agopton
English: However, you still need to take Agopton carefully to get the best results from it.
Slovenian: Vendar morate za najboljše rezultate zdravilo Agopton jemati natančno po navodilih.
English: Each capsule contains <white to pale brownish white entericcoated granules>.
Slovenian: Vsaka kapsula vsebuje <bela do bledo rjavo bela zrnca z gastrorezistentno oblogo>.
English: Thrombocytopenia, eosinophilia, leucopenia
Slovenian: Trombocitopenija, eozinofilija, levkopenija
English: 30 mg once daily for four weeks.
Slovenian: 30 mg enkrat na dan v trajanju 4 tednov.
English: The following side effects are uncommon (occur in less than 1 in 100 patients): - depression - joint or muscle pain - fluid retention or swelling - changes in blood cell counts.
Slovenian: Naslednji neželeni učinki so občasni (pojavijo se pri manj kot 1 bolniku od 100): - depresija, - bolečine v sklepih ali mišicah, - zastajanje tekočine ali otekanje in - spremembe števila krvnih celic.
English: Drugs which inhibit CYP2C19
Slovenian: Zdravila, ki zavirajo CYP2C19
English: • Liver impairment
Slovenian: • Okvare jeter
English: A rapid relief of symptoms is obtained by one capsule (30 mg) daily, and most patients with duodenal ulcer recover within 2 weeks, patients with gastric ulcer and reflux oesophagitis within 4 weeks.
Slovenian: Hitro lajšanje simptomov dosežemo z odmerkom ene kapsule (30 mg) na dan, večina bolnikov z razjedo dvanajstnika okreva v 2 tednih, bolniki z razjedo želodca in refluksnim ezofagitisom pa v 4 tednih.
English: Sucralfate/Antacids:
Slovenian: Sukralfat, antacidi:
English: Agranulocytosis, pancytopenia
Slovenian: Agranulocitoza, pancitopenija
English: The exposure of lansoprazole is several-fold higher in PMs than in extensive metabolisers (EMs).
Slovenian: Pri PM je izpostavljenost lansoprazolu nekajkrat večja kot pri bolnikih z močno presnovo (EM - Extensive Metaboliser).
English: Lansoprazole 30 mg combined with clarithromycin 250 or 500 mg and amoxicillin 1g, or clarithromycin 250 and metronidazole 400-500 mg twice daily was associated with eradication rates meeting the above described requirements.
Slovenian: Lansoprazol 30 mg v kombinaciji s klaritromicinom 250 ali 500 mg in amoksicilinom 1g, ali klaritromicinom 250 in metronidazolom 400-500 mg dvakrat dnevno je izkazal stopnje eradikacije, ki izpolnjujejo zgoraj navedene zahteve.
English: Medicinal products with pH dependent absorption Lansoprazole may interfere with the absorption of drugs where gastric pH is critical to bioavailability.
Slovenian: Lansoprazol lahko ovira absorpcijo zdravil, pri katerih je vrednost pH v želodcu ključna za biološko uporabnost.
English: Preclinical data reveal no special hazards for humans based on conventional studies of safety pharmacology, repeated dose toxicity, toxicity to reproduction or genotoxicity.
Slovenian: Predklinični podatki na podlagi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih, vpliva na sposobnosti razmnoževanja in genotoksičnosti ne kažejo posebnega tveganja za ljudi.
English: The ulcer usually heals within 4 weeks, but in patients not fully healed within this time, the medication may be continued at the same dose for another 4 weeks.
Slovenian: Razjeda se ponavadi zaceli v 4 tednih, vendar se pri bolnikih, ki se ne pozdravijo v tem času, zdravljenje lahko podaljša z istim odmerkom za 4 tedne.
English: A rapid relief of symptoms is obtained by one oro-dispersible tablet (30 mg) daily, and most patients with duodenal ulcer recover within 2 weeks, patients with gastric ulcer and reflux oesophagitis within 4 weeks.
Slovenian: Hitro lajšanje simptomov dosežemo z odmerkom ene orodisperzibilne tablete (30 mg) na dan, večina bolnikov z razjedo dvanajstnika okreva v 2 tednih, bolniki z razjedo želodca in refluksnim ezofagitisom pa v 4 tednih.
English: A restriction regarding food intake is necessary, since effects of food consumption on the pharmacokinetic profile has been observed.
Slovenian: Z ozirom na opažen vpliv uživanja hrane na farmakokinetični profil je omejitev glede uživanja hrane potrebna.
English: • Symptomatic gastroesophageal reflux disease
Slovenian: • Simptomatska gastroezofagealna refluksna bolezen
English: Treatment of infection of Helicobacter pylori: The usual dose is one 30 mg capsule in combination with two different antibiotics in the morning and one 30 mg capsule in combination with two different antibiotics in the evening.
Slovenian: Zdravljenje okužbe z bakterijo Helicobacter pylori: običajni odmerek je ena 30-miligramska kapsula v kombinaciji z dvema različnima antibiotikoma zjutraj in ena 30-miligramska kapsula v kombinaciji z dvema različnima antibiotikoma zvečer.
English: If you stop taking Agopton
Slovenian: Če ste prenehali jemati zdravilo Agopton
English: If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor.
Slovenian: Če kateri koli neželeni učinek postane resen ali če opazite kateri koli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika.
English: The data from the 2 pivotal studies as well as supportive data from the open-label extension study and the comparative study with omeprazole and misoprostol, support the indication: “Treatment of NSAID associated benign gastric and duodenal ulcers in patients requiring continued NSAID treatment”.
Slovenian: Podatki iz dveh osrednjih raziskav, kakor tudi podporni podatki iz odprte razširjene raziskave in primerjalne raziskave z omeprazolom in misoprostolom, podpirajo naslednjo indikacijo: »Zdravljenje benignih razjed želodca in dvanajstnika, povezanih z jemanjem NSAID, pri bolnikih, ki potrebujejo nadaljnje zdravljenje z NSAID.« Raziskave podpirajo pri tej indikaciji uporabo lansoprazola 30 mg enkrat dnevno v trajanju 4 do 8 tednov.
English: After preparing the suspension or mixture, the drug should be administered immediately.
Slovenian: Zdravilo je treba uporabiti takoj po pripravi suspenzije ali zmesi.
English: OPIREN Frash
Slovenian: OPIREN Flas
English: The objective of this trial was to compare the efficacy /safety or lansoprazole 15/30mg to placebo in the prevention of duodenal ulcers in those with a history of duodenal, or gastric ulcer disease in those with a history of gasric ulcers.
Slovenian: Cilj te raziskave je bil primerjati učinkovitost/varnost lansoprazola 15/30 mg s placebom pri preprečevanju razjed dvanajstnika pri bolnikih s predhodno ulkusno boleznijo dvanajstnika oz. preprečevanje razjed želodca pri bolnikih s predhodno ulkusno boleznijo želodca.
English: • Eradication of Helicobacter pylori (H. pylori) concurrently given with appropriate antibiotic therapy for treatment of H.pylori associated ulcers
Slovenian: • eradikacijo Helicobacter pylori (H. pylori) pri sočasni terapiji z ustreznimi antibiotiki za zdravljenje razjed, povezanih s H. pylori
English: The studies presented by the MAH demonstrated efficacy of lansoprazole in the treatment and prevention of gastric ulceration associated with continued intake of NSAIDs.
Slovenian: Raziskave, ki jo je predstavil imetnik dovoljenja za promet z zdravilom, so dokazale učinkovitost lansoprazola pri zdravljenju in preprečevanju razjed na želodcu, povezanih z nadaljnjim jemanjem NSAID.
English: The recommended combinations of antibiotics are: - 30 mg Agopton together with 250-500 mg clarithromycin and 1000 mg amoxicillin - 30 mg Agopton together with 250 mg clarithromycin and 400-500 mg metronidazole
Slovenian: Priporočene kombinacije antibiotikov so: - 30 mg zdravila Agopton skupaj z 250-500 mg klaritromicina in 1000 mg amoksicilina; - 30 mg zdravila Agopton skupaj z 250 mg klaritromicina in 400-500 mg metronidazola.
English: Theophylline:
Slovenian: Teofilin:
English: In patients not fully healed the treatment may be continued for another four weeks.
Slovenian: Pri bolnikih, ki ne okrevajo popolnoma, se zdravljenje lahko podaljša še za štiri tedne.
English: Iceland:
Slovenian: Islandija:
English: The recommended dose is 30 mg of Agopton twice daily for 7 days in combination with one of the following: clarithromycin 250-500 mg twice daily + amoxicillin 1 g twice daily clarithromycin 250 mg twice daily + metronidazole 400-500 mg twice daily
Slovenian: Priporočeni odmerek je 30 mg zdravila Agopton dvakrat na dan 7 dni v eni izmed naslednjih kombinacij: klaritromicin 250-500 mg dvakrat na dan + amoksicilin 1 g dvakrat na dan; klaritromicin 250 mg dvakrat na dan + metronidazol 400-500 mg dvakrat na dan.
English: Glossitis, candidiasis of the oesophagus, pancreatitis, taste disturbances
Slovenian: Glositis, kandidoza požiralnika, pankreatitis, motnje okušanja
English: See enclosed leaflet for further information.
Slovenian: Dodatne informacije so v priloženem navodilu za uporabo.
English: Impaired hepatic or renal function:
Slovenian: Okvara delovanja jeter ali ledvic:
English: Read all of this leaflet carefully because it contains important information for you.
Slovenian: To navodilo vsebuje pomembne informacije, zato ga pozorno preberite.
English: It was demonstrated that the total lansoprazole exposure is many-fold increased in patients with severe hepatic impairment.
Slovenian: Pokazano je bilo, da je skupna izpostavljenost lansoprazolu pri bolnikih z resnimi okvarami jeter večkratno povečana.
English: Monitoring of tacrolimus plasma concentrations is advised when concomitant treatment with lanzoprazole is initiated or ended.
Slovenian: Ob začetku in koncu sočasnega zdravljenja z lansoprazolom se priporoča nadzorovanje koncentracije takrolimusa v plazmi.
English: The H. pylori eradication results obtained when clarithromycin is combined with either amoxicillin or metronidazole give rates of up to 90%, when used in combination with Agopton.
Slovenian: Pri uporabi kombinacije klaritromicina z zdravilom Agopton in amoksicilinom ali metronidazolom se doseže do 90-odstotna eradikacija bakterije H. pylori.
English: Agopton 30 mg: Gastro-resistant granules for oral suspension.
Slovenian: Agopton 30 mg: Gastrorezistentna zrnca za peroralno suspenzijo.
English: No clinically relevant difference in ulcer prevention between the 15 and 30 mg dose of lansoprazole could be demonstrated.
Slovenian: Med odmerkoma 15 in 30 mg lansoprazola ni bilo mogoče dokazati nobene klinično pomembne razlike z vidika preprečevanja nastanka razjed.
English: Lansoprazole should not be co-administered with atazanavir (see section
Slovenian: Lansoprazol se ne sme uporabljati skupaj z atazanavirom (glejte poglavje 4.3).
English: This is reflected in the SPC under section 4.2 and 5.2.
Slovenian: To je razvidno iz poglavij 4.2 in 5.2 SPC.
English: Treatment of infection of Helicobacter pylori: The usual dose is one 30 mg oro-dispersible tablet in combination with two different antibiotics in the morning and one 30 mg oro-dispersible tablet in combination with two different antibiotics in the evening.
Slovenian: Zdravljenje okužbe z bakterijo Helicobacter pylori: običajni odmerek je ena 30-miligramska orodisperzibilna tableta v kombinaciji z dvema različnima antibiotikoma zjutraj in ena 30-miligramska orodisperzibilna tableta v kombinaciji z dvema različnima antibiotikoma zvečer.
English: Please refer to section 4.8 for possible symptoms of lansoprazole overdose.
Slovenian: Možni simptomi prevelikega odmerjanja lansoprazola so v poglavju 4.8.
English: Medicinal products metabolised by P450 enzymes Lansoprazole may increase plasma concentrations of drugs that are metabolised by CYP3A4.
Slovenian: Lansoprazol lahko poveča koncentracije zdravil, ki jih presnavlja CYP3A4, v plazmi.
English: Each 30 mg oro-dispersible tablet contains 30 mg of lactose and 9.0 mg of aspartame For a full list of excipients, see section 6.1.
Slovenian: Vsaka 30-miligramska orodisperzibilna tableta vsebuje 30 mg laktoze in 9,0 mg aspartama.
English: Greece:
Slovenian: Grčija:
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER [See Annex I - To be completed nationally]
Slovenian: IME IN NASLOV IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM [Glejte Dodatek I - Izpolni država članica.]
English: Agopton and associated names (see Annex I) 15 mg capsules Agopton and associated names (see Annex I) 30 mg capsules
Slovenian: Agopton in povezana imena (glejte Dodatek I) 15 mg kapsule Agopton in povezana imena (glejte Dodatek I) 30 mg kapsule
English: Member State Marketing Authorisation Holder
Slovenian: Država članica Imetnik dovoljenja za promet z zdravilom Ime izdelka
English: The recommended dose is 30 mg once daily for 2 weeks.
Slovenian: Priporočeni odmerek je 30 mg enkrat na dan v trajanju 2 tednov.
English: Gastric acid is central in the pathogenesis of gastroduodenal ulcers and acid inhibition has been shown to effectively heal NSAID-associated ulcers.
Slovenian: Želodčna kislina ima ključno vlogo pri nastanku in razvoju razjed želodca in dvanajstnika, zaviranje izločanja želodčne kisline pa se je izkazalo kot učinkovito pri celjenju razjed, povezanih z NSAID.
English: Prophylaxis of NSAID associated gastric and duodenal ulcers in patients at risk (such as age > 65 or history of gastric or duodenal ulcer) requiring prolonged NSAID treatment:
Slovenian: Profilaksa razjed dvanajstnika in želodca, povezanih z NSAID pri bolnikih, pri katerih obstaja tveganje (kot je starost > 65 let ali razjeda dvanajstnika in želodca v anamnezi) in pri katerih je potrebno neprekinjeno zdravljenje z NSAID:
English: Therefore lansoprazole should be taken at least 1 hour after taking these drugs.
Slovenian: Sukralfat in antacidi lahko zmanjšajo biološko uporabnost lansoprazola, zato je treba lansoprazol vzeti vsaj eno uro po uporabi teh zdravil.