FrancophonIA/ELRC3.0 huggingface dataset:
English: c Nocturnal hypoglycaemia: Episode that occurred between 00:00 and 05:59 hours d 6-month treatment period
Slovenian: c Nočna hipoglikemija: hipoglikemija, ki se je pojavila med 00:00 in 05:59.
English: It is unknown whether insulin glargine is excreted in human milk.
Slovenian: Ni znano, ali se insulin glargin pri človeku izloča v mleku.
English: Hypoglycaemia can be very serious and is very common with insulin treatment (may affect more than 1 in 10 people).
Slovenian: Hipoglikemija je lahko zelo resna in je med zdravljenjem z insulinom zelo pogosta (pojavi se lahko pri več kot 1 od 10 oseb).
English: • Changes in taste (dysgeusia).
Slovenian: • Spremembe okusa (dizgevzija).
English: Check your blood sugar and eat more food to prevent you blood sugar getting too low.
Slovenian: Kontrolirajte si krvni sladkor in uživajte več hrane, da boste preprečili pretirano znižanje krvnega sladkorja.
English: • You have not injected your insulin or not injected enough.
Slovenian: • Niste si injicirali insulina ali si ga niste injicirali dovolj.
English: • Muscular pain (myalgia).
Slovenian: • Mišične bolečine (mialgija).
English: If normal or decreased values for glycated haemoglobin are noted, the possibility of recurrent, unrecognised (especially nocturnal) episodes of hypoglycaemia must be considered.
Slovenian: Če se pojavijo normalne ali znižane vrednosti glikoziliranega hemoglobina, je treba pomisliti na možnost ponavljajočih se, neugotovljenih (zlasti nočnih) hipoglikemij.
English: Annex IV Scientific conclusions and grounds for the variation to the terms of the marketing authorisation(s)
Slovenian: Priloga IV Znanstveni zaključki in podlaga za spremembo pogojev dovoljenja za promet z zdravilom
English: Patients who forget a dose, should be advised to check their blood sugar and then resume their usual once-daily dosing schedule.
Slovenian: Bolnikom, ki pozabijo uporabiti odmerek, je treba svetovati, naj si kontrolirajo krvni sladkor in nato nadaljujejo uporabo po urniku odmerjanja enkrat na dan.
English: If you do you will get too much insulin.
Slovenian: Če to storite, boste dobili preveč insulina.
English: • You have recently changed from an animal insulin to a human insulin, like Toujeo.
Slovenian: • ste pred kratkim prešli z živalskega insulina na humani insulin, kot je na primer zdravilo
English: When needed, patients can administer Toujeo up to 3 hours before or after their usual time of administration (see section 5.1).
Slovenian: Če je treba, lahko bolniki zdravilo Toujeo uporabijo do 3 ure pred ali po običajnem času uporabe (glejte poglavje 5.1).
English: The strength“300” is highlighted in honey gold on the label (see section 4.4).
Slovenian: Jakost "300" je označena na nalepki z medeno zlato barvo (glejte poglavje 4.4).
English: If you inject insulin too often at the same place, the skin may either shrink (lipoatrophy, may affect up to 1 in 100 people) or thicken (lipohypertrophy, may affect up to 1 in 10 people).
Slovenian: Če insulin prepogosto injicirate na isto mesto, se koža lahko skrči (lipoatrofija, ki se lahko pojavi pri največ 1 od 100 oseb) ali zadebeli (lipohipertrofija, ki se lahko pojavi pri največ 1 od 10 oseb).
English: The educational materials consist of:
Slovenian: Izobraževalno gradivo sestoji iz:
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Slovenian: Preobčutljivost na učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1
English: • Patient/carer guide (patient brochure)
Slovenian: • Vodnika za bolnike/skrbnike (brošura za bolnike)
English: RR: 0.87 [0.48;1.55]
Slovenian: RT: 0,87 [0,48;1,55]
English: • Toujeo is injected under the skin (subcutaneous use or “SC”).
Slovenian: • Zdravilo Toujeo se injicira pod kožo (subkutana uporaba ali "s.c.").
English: The time of occurrence of hypoglycaemia depends on the action profile of the insulins used and may, therefore, change when the treatment regimen is changed.
Slovenian: Čas pojava hipoglikemije je odvisen od profila delovanja uporabljenih insulinskih zdravil, zato se ob spremembi sheme zdravljenja lahko spremeni.
English: Patients must visually verify the number of selected units on the dose counter of the pen.
Slovenian: Bolniki morajo z ogledom preveriti število izbranih enot na odmernem okencu injekcijskega peresnika.
English: Severe allergic reactions may become life-threatening.
Slovenian: Hude alergijske reakcije lahko postanejo smrtno nevarne.
English: So, before taking a medicine ask your doctor if it will affect your blood sugar and what action, if any, you need to take.
Slovenian: Zato pred uporabo zdravila, zdravnika vprašajte, ali bo vplivalo na krvni sladkor, ali je v zvezi s tem potrebno kakšno posebno ravnanje in če, kakšno.
English: You should check your blood sugar level more than usual.
Slovenian: Krvni sladkor si morate kontrolirati pogosteje kot po navadi.
English: Do not freeze or place next to the freezer compartment or a freezer pack.
Slovenian: Ne zamrzujte in ne shranjujte v bližini zmrzovalniškega razdelka ali v bližini zmrzovalniških vložkov.
English: • If you do not follow all of these instructions, you may get too much or too little insulin.
Slovenian: • Če ne upoštevate vseh teh navodil, lahko dobite preveč ali premalo insulina.
English: The dose delivered is the one shown in the dose window.
Slovenian: Odmerek, ki bo injiciran, je tisti, ki je prikazan v odmernem okencu.
English: Type 2 diabetic patients (n=194) received Toujeo once daily in the evening, either at the same time of the day (fixed time of administration) or within 3 hours before or after the usual time of administration (flexible dosing time).
Slovenian: Bolniki s sladkorno boleznijo tipa 2 (n = 194) so prejemali zdravilo Toujeo enkrat na dan zvečer, in sicer ali vsak dan ob istem času (fiksni čas uporabe) ali v obdobju 3 ur pred ali po običajnem času uporabe (prilagodljivi čas uporabe).
English: The pen is recommended for patient who need at least 20 units of insulin per day (see also section 2).
Slovenian: Injekcijski peresnik se priporoča bolnikom, ki potrebujejo vsaj 20 enot insulina na dan (glejte tudi poglavje 2).
English: • You have an injury, infection or fever or have had an operation.
Slovenian: • Imate kakšno poškodbo, okužbo ali zvišano telesno temperaturo, ali ste imeli operacijo.
English: SoloStar pen1 step=1 unit DoubleStar pen 1 step=2 units
Slovenian: SoloStar peresnik 1 odmerni korak=1 enota DoubleStar peresnik 1 odmerni korak=2 enoti
English: Odd numbers are shown as a line between even numbers:
Slovenian: Liha števila so prikazana kot črtice med sodimi števili:
English: • Always check the number in the dose window to make sure you dialled the correct dose
Slovenian: • Vedno preverite število odmerkov, ki je nastavljeno v odmernem okencu in se prepričajte, da ste nastavili ustrezen odmerek zdravila.
English: • Fluoxetine - for depression.
Slovenian: • Fluoksetin - za depresijo.
English: • Sympathomimetic medicines such as epinephrine (adrenaline), salbutamol and terbutaline - for asthma.
Slovenian: • Simpatikomimetična zdravila, na primer adrenalin, salbutamol in terbutalin - za astmo.
English: • Clozapine, olanzapine and phenothiazine derivatives - for mental health problems.
Slovenian: • Klozapin, olanzapin in derivate fenotiazina - za težave z duševnim zdravjem.
English: • a puncture resistant container for used needles and pens.
Slovenian: • proti prebadanju odporen vsebnik za uporabljene igle in peresnike.
English: Diabetes mellitus is an illness where your body does not make enough insulin to control your blood sugar.
Slovenian: Sladkorna bolezen je bolezen, pri kateri telo ne izdeluje dovolj insulina za uravnavanje krvnega sladkorja.
English: Instruct patients to perform a safety test as described in Step 3 of the Instructions for Use.
Slovenian: Bolnikom naročite, naj opravijo varnostni preizkus, kot je opisano v 3. koraku Navodil za uporabo.
English: This medicine should not be used in children under 6 years of age.
Slovenian: Tega zdravila ne smejo uporabljati otroci, mlajši od 6 let.
English: Administration with a flexible dosing time had no effect on glycaemic control and the incidence of hypoglycaemia.
Slovenian: Uporaba s prilagodljivim časom ni vplivala na urejenost glikemije ali incidenco hipoglikemij.
English: If you have any questions about your pen or about diabetes, ask your doctor, pharmacist or nurse or call sanofi-aventis number on the front of this leaflet.
Slovenian: Če imate vprašanja o peresniku ali o sladkorni bolezni, se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro, ali pokličite številko družbe sanofi-aventis d.o.o., ki je napisana na sprednji strani tega navodila.
English: They do not help treat low blood sugar.
Slovenian: Te namreč ne pomagajo odpraviti nizkega krvnega sladkorja.
English: The use of Toujeo may be considered during pregnancy, if clinically needed.
Slovenian: Uporaba zdravila Toujeo pride med nosečnostjo v poštev, če je klinično potrebna.
English: B Keep the needle straight and screw it onto the pen until fixed.
Slovenian: B Iglo držite naravnost in jo privijte na peresnik, dokler ni do konca pritrjena.
English: If they don't, the full dose might not be delivered.
Slovenian: Če tega ne naredijo, se lahko zgodi, da ne prejmejo celotnega odmerka.
English: Pharmacotherapeutic group: Drugs used in diabetes, insulins and analogues for injection, long-acting.
Slovenian: Farmakoterapevtska skupina: zdravila za zdravljenje diabetesa, insulini z dolgotrajnim delovanjem in analogi, za injiciranje.
English: Changes in strength, brand (manufacturer), type (regular, NPH, lente, longacting, etc.), origin (animal, human, human insulin analogue) and/or method of manufacture may result in the need for a change in dose (see section 4.2).
Slovenian: Spremembe jakosti, trgovske znamke (izdelovalec), vrste (običajni humani insulin, NPH, Lente, dolgodelujoči), izvora (živalski, humani, analog humanega insulina) in/ali načina izdelave lahko povzročijo, da je potrebna sprememba odmerka (glejte poglavje 4.2).
English: The safety and efficacy of Toujeo administered with a fixed or flexible dosing time were also evaluated in 2 randomized, open-label clinical studies for 3 months.
Slovenian: Varnost in učinkovitost zdravila Toujeo, uporabljenega s fiksnim ali prilagodljivim časom odmerjanja, so ocenili tudi v 2 randomiziranih, odprtih 3-mesečnih kliničnih študijah.
English: Do not leave your insulin in a car on an exceptionally warm or cold day.
Slovenian: Ob zelo vročih ali zelo hladnih dneh ne puščajte insulina v avtu.
English: Examples include:
Slovenian: Med takšnimi dejavniki so:
English: Immediately after delivery, insulin requirements decline rapidly (increased risk of hypoglycaemia).
Slovenian: Takoj po porodu se potreba po insulinu hitro zmanjša (zato obstaja večje tveganje za hipoglikemije).
English: Patients who are blind or have poor vision should be instructed to get help/assistance from another person who has good vision and is trained in using the insulin device.
Slovenian: Bolnikom, ki so slepi ali slabovidni, je treba naročiti, naj jim pomaga oseba, ki dobro vidi in je usposobljena za uporabo tega insulinskega pripomočka.
English: Improvement in HbA1C was not affected by, gender, ethnicity, age, diabetes duration (<10 years and ≥10 years), HbA1c value at baseline (<8% or ≥8%) or baseline body mass index (BMI).
Slovenian: Na izboljšanje HbA1C niso vplivali spol, etnična pripadnost, starost, trajanje sladkorne bolezni (< 10 let in ≥ 10 let), izhodiščna vrednost HbA1C (< 8 % ali ≥ 8 %) izhodiščni indeks telesne mase (ITM).
English: • Corticosteroids such as cortisone - for inflammation.
Slovenian: • Kortikosteroide, kot je na primer kortizon - za vnetje.
English: If you have kidney or liver problems, talk to your doctor as you may need a lower dose.
Slovenian: Če imate težave z ledvicami ali jetri, se posvetujte z zdravnikom, ker boste morda potrebovali manjši odmerek.
English: • Protease inhibitors- for HIV.
Slovenian: • Zaviralce proteaz - za HIV.
English: This should be kept in mind if treatment with the combination of pioglitazone and Toujeo is considered.
Slovenian: To je treba upoštevati pri zdravljenju s kombinacijo pioglitazona in zdravila Toujeo.
English: There were no differences between insulin glargine and standard care for the two co-primary outcomes; for any component endpoint comprising these outcomes; for all-cause mortality; or for the composite microvascular outcome.
Slovenian: Med insulinom glargin in standardno oskrbo ni bilo razlik pri dveh soprimarnih izidih; pri katerem koli elementu, ki je vključeval ta izida, pri umrljivosti zaradi vseh vzrokov ali pri sestavljenem mikrovaskularnem izidu.
English: On the basis of the scientific conclusions for insulin glargine the CHMP is of the opinion that the benefit-risk balance of the medicinal product(s) containing insulin glargine is unchanged subject to the proposed changes to the product information
Slovenian: Na podlagi znanstvenih zaključkov za insulin glargin odbor CHMP meni, da je razmerje med koristjo in tveganjem zdravil(-a), ki vsebuje(-jo) insulin glargin nespremenjeno ob upoštevanju predlaganih sprememb v informacijah o zdravilu.
English: Careful monitoring of glucose control is essential.
Slovenian: Nujno je skrbno nadziranje urejenosti glikemije.
English: This may damage your pen.
Slovenian: To lahko poškoduje peresnik.
English: This may mean your insulin dose has to change.
Slovenian: To lahko pomeni, da bo treba spremeniti odmerek insulina.
English: Do not perform any dose re-calculation.
Slovenian: Ne opravljajte nobenih ponovnih izračunov odmerka.
English: • Oestrogens and progestogens - such as in the contraceptive pill for birth control.
Slovenian: • Estrogene in progestagene - na primer v kontracepcijskih tabletah za preprečevanje nosečnosti.
English: Most minor reactions to insulins at the injection site usually resolve in a few days to a few weeks.
Slovenian: Večina blažjih reakcij na insuline na mestu injiciranja po navadi mine v nekaj dneh do nekaj tednih.
English: Pharmacokinetic profiles were consistent with the pharmacodynamic activity of Toujeo.
Slovenian: Farmakokinetične značilnosti so se skladale s farmakodinamično aktivnostjo zdravila Toujeo.
English: B Press the injection button all the way in.
Slovenian: B Pritisnite gumb za injiciranje do konca noter.
English: • Lithium salts - for mental health problems.
Slovenian: • Litijeve soli - za težave z duševnim zdravjem.
English: • Never use your pen after the expiration date.
Slovenian: • Peresnika nikdar ne uporabljajte po datumu izteka roka uporabnosti.
English: Toujeo pre-filled pens have to be used as recommended in these Instructions for Use (see section 4.2).
Slovenian: Napolnjene injekcijske peresnike Toujeo je treba uporabljati, kot je priporočeno v teh navodilih za uporabo (glejte poglavje 4.2).
English: For insulin glargine no clinical data on exposed pregnancies from controlled clinical studies are available.
Slovenian: Za insulin glargin iz kontroliranih kliničnih študij ni kliničnih podatkov o izpostavljenih nosečnicah.
English: Steady state level within the therapeutic range is reached after 3-4 days of daily Toujeo administration.
Slovenian: Stanje dinamičnega ravnovesja je v terapevtskem območju doseženo po 3 do 4 dneh uporabe zdravila Toujeo.
English: Used needles should be thrown away in a puncture resistant container or disposed of in accordance with local requirements.
Slovenian: Uporabljene igle je treba vreči v posodo za odlaganje ostrih odpadkov ali odstraniti v skladu z lokalnimi predpisi.
English: This could cause high blood sugar.
Slovenian: Posledica je lahko visok krvni sladkor.
English: Flexibility in dosing time
Slovenian: Prilagodljivost časa uporabe
English: Switching from the 300 units/ml to the 100 units/ml concentration results in an increased risk of hypoglycaemic events, mainly in the first week after the switch.
Slovenian: Prehod z jakosti 300 enot/ml na 100 enot/ml poveča tveganje za hipoglikemijo, predvsem v prvem tednu po prehodu.
English: More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular/subcutaneous glucagon or concentrated intravenous glucose.
Slovenian: Hujše primere s komo, konvulzijami ali nevrološko prizadetostjo je mogoče zdraviti z glukagonom intramuskularno ali subkutano ali s koncentrirano glukozo intravensko.
English: If you find it hard to press the injection button in, do not force it as this may break your pen.
Slovenian: Če gumb za injiciranje težko pritisnete noter, ne uporabite sile, ker lahko poškodujete peresnik.
English: Long-term improved glycaemic control decreases the risk of progression of diabetic retinopathy.
Slovenian: Dolgoročno izboljšanje urejenosti glikemije zmanjša tveganje za napredovanje diabetične retinopatije.
English: Toujeo must not be mixed or diluted with any other insulin or other medicinal products.
Slovenian: Zdravila Toujeo se ne sme mešati ali redčiti z nobenim drugim insulinom ali kakšnim drugim zdravilom.
English: Efficacy and safety data for paediatric patients with type 2 diabetes mellitus have been extrapolated from data for adolescent and adult patients with type 1 diabetes mellitus and adult patients with type 2 diabetes mellitus.
Slovenian: Podatke o učinkovitosti in varnosti za pediatrične bolnike s sladkorno boleznijo tipa 2 so ekstrapolirali iz podatkov za mladostnike in odrasle bolnike s sladkorno boleznijo tipa 1 in iz podatkov za odrasle bolnike s sladkorno boleznijo tipa 2.
English: Change the injection site with each injection to help prevent these skin changes.
Slovenian: Mesto injiciranja menjajte ob vsaki injekciji, da preprečite takšne kožne spremembe.
English: The frequency, type and severity of adverse reactions in the paediatric population do not indicate differences to the experience in the general diabetes population (see section 5.1).
Slovenian: Pogostnost, vrsta in izrazitost neželenih učinkov se v pediatrični populaciji ne razlikujejo od tistih v splošni populaciji s sladkorno boleznijo (glejte poglavje 5.1).
English: Insulin and its analogues lower blood glucose levels by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production.
Slovenian: Insulin in njegovi analogi zmanjšajo koncentracijo glukoze v krvi s spodbujanjem perifernega privzema glukoze, zlasti v skeletnem mišičju in maščevju, ter z zaviranjem tvorbe glukoze v jetrih.
English: These units are exclusive to Toujeo and are not the same as IU or the units used to express the potency of other insulin analogues (see section 5.1).
Slovenian: Te enote veljajo izključno za zdravilo Toujeo in niso enake mednarodnim enotam (i.e.) ali enotam, ki se uporabljajo za izražanje jakosti drugih insulinskih analogov (glejte poglavje 5.1).
English: Get help from a person with good eye sight who is trained in using the pen.
Slovenian: Pomaga naj vam oseba, ki dobro vidi in je usposobljena za uporabo peresnika.
English: • Low blood sugar means that there is not enough sugar in your blood.
Slovenian: • Nizek krvni sladkor pomeni, da v krvi ni dovolj sladkorja.
English: IGlar: Insulin glargine 100 units/ml a Severe hypoglycaemia: Episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions.
Slovenian: IGlar: Insulin glargin 100 enot/ml a Huda hipoglikemija: hipoglikemija, ki zahteva pomoč druge osebe za aktivno uporabo ogljikovih hidratov, glukagona ali drugih rešilnih ukrepov.
English: - If you are allergic to insulin glargine or to any of the other ingredients of this medicine (listed in section 6).
Slovenian: Ne uporabljajte zdravila Toujeo - Če ste alergični na insulin glargin ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Paediatric population Population pharmacokinetic analysis was conducted for Toujeo based on concentration data of its main metabolite M1 using data from 75 pediatric subjects (6 to <18 years of age) with type 1 diabetes.
Slovenian: Populacijsko farmakokinetično analizo so za zdravilo Toujeo opravili na podlagi podatkov o koncentraciji njegovega glavnega presnovka M1; v ta namen so uporabili podatke 75 pediatričnih bolnikov (starih od 6 do < 18 let) s sladkorno boleznijo tipa 1.
English: After subcutaneous injection of insulin glargine, insulin glargine is rapidly metabolized at the carboxyl terminus of the Beta chain with formation of two active metabolites M1 (21A-Gly-insulin) and M2 (21A-Gly-des-30B-Thr-insulin).
Slovenian: Po subkutanem injiciranju insulina glargin se ta hitro presnovi na karboksilnem koncu verige beta; nastaneta aktivna presnovka M1 (21A-Gly-insulin) in M2 (21A-Gly-des-30B-Thr-insulin).
English: Also lumps under the skin caused by build-up of a protein called amyloid may occur (cutaneous amyloidosis, how often they occur is not known).
Slovenian: Zaradi kopičenja beljakovine imenovane amiloid, se lahko pojavijo podkožne grudice (kožna amiloidoza; ni znano, kako pogosto se pojavlja).
English: In the elderly, progressive deterioration of renal function may lead to a steady decrease in insulin requirements (see section 4.8 and 5.1).
Slovenian: Pri starejših bolnikih lahko napredujoče slabšanje delovanja ledvic povzroči stalno zmanjševanje potrebe po insulinu (glejte poglavji 4.8 in 5.1).
English: Insulin glargine is metabolised into 2 active metabolites M1 and M2 (see section 5.2).
Slovenian: Insulin glargin se presnovi v dva aktivna presnovka, M1 in M2 (glejte poglavje 5.2).
English: The MAH shall agree the final text and the context of the educational material for HCPs and patients together with a communication plan, with the National Competent Authority in each Member State prior to launch of the medicinal product.
Slovenian: Imetnik dovoljenja za promet z zdravilom se mora o končnem besedilu in kontekstu izobraževalnega gradiva z zdravstvene delavce in bolnike ter o načrtu razdeljevanja dogovoriti s pristojnim nacionalnim organom v vsaki državi članici pred prihodom zdravila na trg.
English: • You inject too much insulin.
Slovenian: • Injicirate si preveč insulina.
English: Solution for injection (injection).
Slovenian: FARMACEVTSKA OBLIKA Raztopina za injiciranje (injekcija).
English: The half-life of Toujeo after subcutaneous injection is 18-19 hours independent of dose.
Slovenian: Razpolovni čas zdravila Toujeo po subkutani injekciji je od 18 do 19 ur, neodvisno od odmerka.
English: Toujeo is not the insulin of choice for the treatment of diabetic ketoacidosis.
Slovenian: Zdravilo Toujeo ni insulin prve izbire za zdravljenje diabetične ketoacidoze.
English: Tell your doctor, pharmacist or nurse if you notice any of the following side effects:
Slovenian: Zdravniku, farmacevtu ali medicinski sestri povejte, če opazite katerega od naslednjih neželenih učinkov:
English: At the end of these treat-to-target trials, depending on the patient population and concomitant therapy, a 10-18% higher dose was observed in the Toujeo group than in the comparator group (Table 1 and
Slovenian: Na koncu teh preskušanj z zdravljenjem do cilja so-odvisno od populacije bolnikov in sočasnih zdravil-v skupini z zdravilom Toujeo opažali od 10 do 18% večje odmerke kot v primerjalni skupini (preglednici 1 in 2).
English: This medicinal product contains less than 1 mmol (23 mg) sodium per dose, i.e. it is essentially ‘sodium-free'.
Slovenian: Pomožne snovi To zdravilo vsebuje manj kot 1mmol (23mg) natrija na odmerek, kar v bistvu pomeni 'brez natrija'.
English: In many patients, the signs and symptoms of neuroglycopenia are preceded by signs of adrenergic counter-regulation.
Slovenian: Številnim bolnikom se pred znaki in simptomi nevroglikopenije pojavijo znaki adrenergične protiregulacije.
English: Use only clear and colourless solutions.
Slovenian: Uporabite samo bistro in brezbarvno raztopino.
English: • Key messages to convey in patients counselling: - Patients need to be instructed that insulin glargine 100 units/ml products and Toujeo are not interchangeable and dose adjustments need to be made;
Slovenian: • Ključna sporočila, ki jih je treba posredovati pri svetovanju bolnikom: - Bolnikom je treba povedati, da zdravila z insulinom glargin 100 enot/ml in zdravilo Toujeo niso medsebojno zamenljivi in da je treba odmerek prilagoditi.