FrancophonIA/ELRC3.0 huggingface dataset:
English: The expiry date refers to the last day of that month.
Maltese: Issinjifikat ta' dawn il-bidliet mhuwiex magħruf.
English: Because of the potential of receiving higher doses of chemotherapy (e.g. full doses on the prescribed schedule) the patient may be at greater risk of thrombocytopenia and anaemia.
Maltese: dawn il-mediċini waqt kura b'filgrastim, jista' jkun hemm riskju ogħla li l-pazjent jiżviluppa tromboċitopenja u anemija.
English: In patients undergoing a stem cell or bone marrow transplant, Graft versus host disease (GvHD) may occur - this is a reaction of the donor cells against the patient receiving the transplant; signs and symptoms include rash on the palms of your hands or soles of your feet and ulcer and sores in your mouth, gut, liver, skin, or your eyes, lungs, vagina and joints.
Maltese: F'pazjenti li jkunu għaddejjin minn trapjant taċ-ċelluli staminali jew tal-mudullun, tista' sseħħ il-Marda ta' graft kontra l-ospitu (Graft versus host disease - GvHD) - din hija reazzjoni taċċelluli donaturi kontra l-pazjent li jirċievi t-trapjant; is-sinjali u s-sintomi jistgħu jinkludu raxx fuq ilpali ta' jdejk jew il-qiegħ ta' saqajk u ulċera u feriti f'ħalqek, fl-imsaren, fil-fwied, fil-ġilda, jew f'għajnejk, fil-pulmun, fil-vaġina jew fil-ġogi.
English: Discontinue filgrastim
Maltese: Infiltrazzjoni talpulmun
English: In view of the possible risk of microbial contamination, Nivestim syringes are for single use only.
Maltese: Minħabba r-riskju potenzjali ta' kontaminazzjoni bil-mikrobi, issiringi ta' Nivestim iridu jintużaw darba biss.
English: The use of filgrastim-mobilised PBPCs has been shown to reduce the depth and duration of thrombocytopenia following myelosuppressive or myeloablative chemotherapy.
Maltese: Tromboċitopenija ġiet irrappurtata f'pazjenti li kienu qed jirċievu filgrastim.
English: Nivestim containing r-metHuG-CSF (filgrastim) causes marked increases in peripheral blood neutrophil counts within twenty four hours, with minor increases in monocytes.
Maltese: Nivestim, li fih r-metHuG-CSF (filgrastim) jikkawża żjieda notevoli fl-għadd ta' newtrofili fid-demm periferali fi żmien 24 siegħa, b'żjidiet minuri fil-monoċiti.
English: Although this interaction has not been formally investigated, there is no evidence that such an interaction is harmful.
Maltese: Għalkemm din l-interazzjoni ma ġietx speċifikament investigata, m'hemm l-ebda evidenza li interazzjoni bħal din tista' tkun ta' ħsara.
English: However, the administration of melphalan, carboplatin or BCNU together with filgrastim has been shown to be effective for progenitor mobilisation.
Maltese: Madankollu, intwera li l-amministrazzjoni ta' melphalan, carboplatin jew BCNU flimkien ma' filgrastim kien effettiv fil-mobilizzazzjoni taċ-ċelluli proġenitriċi.
English: Cases of capillary leak syndrome have been reported with granulocyte colony-stimulating factor use.
Maltese: Każijiet ta' sindromu ta' tnixxija tal-kapillari (capillary leak syndrome) kienu rrappurtati mal-użu ta' fatturi li jistimulaw kolonji granuloċitiċi.
English: The long-term safety of filgrastim administration above 24 µg/kg/day in patients with SCN has not been established.
Maltese: Is-sigurtà assoċjata malamministrazzjoni fit-tul ta' filgrastim f'dozi akbar minn 24 µg/kg/jum f'pazjenti b'SCN għadha ma ġietx stabilita.
English: In clinical studies, > 90% of patients responded at these doses, achieving reversal of neutropenia in a median of 2 days.
Maltese: Fi studji kliniċi, > 90 % tal-pazjenti rrispondu b'dawn id-dożi, u kellhom taqlib ta' newtropenja f'medda ta' jumejn.
English: In other circumstances, additional leukapheresis is recommended.
Maltese: F'ċirkostanzi oħrajn, hija rakkomandata lewkafereżi addizzjonali.
English: Pack sizes of 1, 5, 8 or 10 pre-filled syringes.
Maltese: Pakketti ta' 1, 5, 8 jew 10 siringi mimlijin għal-lest
English: Data from clinical studies in paediatric patients indicate that the safety and efficacy of filgrastim are similar in both adults and children receiving cytotoxic chemotherapy suggesting no age-related differences in the pharmacokinetics of filgrastim.
Maltese: Dejta minn studji kliniċi f'pazjenti pedjatriċi juru li s-sigurtà u l-effikaċja ta' filgrastim huma simili kemm fl-adulti kif ukoll fit-tfal li jirċievu kimoterapija ċitotossika, u tissuġġerixxi għalhekk li m'hemm l-ebda differenza marbuta mal-età fil-farmakokinetika ta' filgrastim.
English: Upper respiratory tract infection
Maltese: Infezzjoni flapparat respiratorju ta' fuq
English: In normal donors, a 10 µg/kg/day dose administered subcutaneously for 4 to 5 consecutive days allows a collection of ≥ 4 x 10
Maltese: F'donaturi normali, doża ta' 10 µg/kg/jum mogħtija taħt il-ġilda għal 4 sa 5 ijiem konsekuttivi tippermetti l-ġbir ta' ≥ 4 x 10
English: Following subcutaneous administration of recommended doses, serum concentrations were maintained above 10 ng/ml for 8 to 16 hours.
Maltese: Wara l-amministrazzjoni taħt il-ġilda tad-doża rakkomandata, il-konċentrazzjoni fis-serum nżammet 'il fuq minn 10 ng/mL għal 8 sa 16-il siegħa.
English: • Antiseptic wipes (if recommended by your doctor or nurse).
Maltese: • Msieħ antisettiku (jekk ikun rakkomandat mit-tabib jew infermiera).
English: Keep the pre-filled syringe in the outer carton in order to protect from light.
Maltese: Ematurja kienet komuni u proteinurja seħħet f'numru żgħir ta' pazjenti.
English: Permanently discontinue filgrastim in patients with clinically significant hypersensitivity.
Maltese: Waqqaf filgrastim għal kollox f'pazjenti f'sensittività eċċessiva li hija klinikament sinifikanti.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C to 8°C, unless dilution has taken place in controlled and validated aseptic conditions.
Maltese: Jekk ma jintużax immedjatament, il-perjodu u l-kundizzjonijiet tal-ħażna qabel l-użu huma r-responsabilità ta' min jużah u normalment ma jkunx ta' iktar minn 24 siegħa f'temperatura ta' bejn 2 °C - 8 °C, sa kemm d-dilwazzjoni ma tkunx seħħet f'kundizzjonijiet asettiċi kontrollati u vvalidati.
English: For patients treated with filgrastim diluted to concentrations below 1.5 MU (15 µg) per ml, human serum albumin (HSA) should be added to a final concentration of 2 mg/ml.
Maltese: MU (15 µg)/mL, din trid tiġi miżjuda bl-albumina tas-serum uman (HSA) sabiex ilkonċentrazzjoni finali tkun 2 mg/mL.
English: Use of filgrastim in patients, children or adults, with SCN (severe congenital, cyclic, and idiopathic neutropenia) induces a sustained increase in absolute neutrophil counts in peripheral blood and a reduction of infection and related events.
Maltese: L-użu ta' filgrastim f'pazjenti, tfal u adulti, b'SCN (newtropenja qawwija, konġenitali, ċiklika, u idjopatika) iwassal għal żjieda sostenibbli fl-għadd assolut ta' newtrofili fid-demm periferali u tnaqqis fin-numru ta' infezzjonijiet u ġrajjiet relatati.
English: The pre-filled syringe has an UltraSafe Needle Guard attached in order to protect from needle stick injury.
Maltese: Is-siringa mimlija lesta għandha Ultrasafe Needle Guard mwaħħla magħha sabiex tipproteġi minn ferrimenti li jistgħu jinqalgħu mil-labra.
English: Offspring of rats administered filgrastim during the peri-natal and lactation periods, exhibited a delay in external differentiation and growth retardation (≥ 20 µg/kg/day) and slightly reduced survival rate (100 µg/kg/day).
Maltese: Iż-żgħar tal-firien mogħtija filgrastim waqt il-perjodi ta' madwar it-twelid u t-treddigħ, wera li l-bidliet esterni u l-iżvilupp seħħew tard (> 20 µg/kg/jum) u rata ta' sopravivenza kienet kemxejn imnaqqsa (100 µg/kg/jum.
English: The symptoms experienced included fever, abdominal pain, malaise, back pain and increased inflammatory markers (e.g. C-reactive protein and white blood cell count).
Maltese: Issintomi li ħassew kienu jinkludu deni, uġigħ fl-addome, telqa, uġigħ fid-dahar u żieda fil-markaturi infjammatorji (eż. proteina C-reattiva u għadd ta' ċelloli bojod tad-demm).
English: • decreased feeling of sensitivity, especially in the skin (hypoaesthesia)
Maltese: • tnaqqis fis-sensittività, speċjalment fil-ġilda (ipoesteżija)
English: Rate of generation of antibodies against filgrastim is generally low.
Maltese: Ir-rata ta' ġenerazzjoni ta' antikorpi kontra filgrastim hija ġeneralment baxxa.
English: Recipients of allogeneic PBPCs mobilised with filgrastim experienced significantly more rapid haematological recovery, leading to a significant decrease in time to unsupported platelet recovery when compared with allogeneic bone marrow transplantation.
Maltese: Il-proċedura ta' mobilizzazzjoni ta' PBPC trid tiġi kkunsidrata biss għal donaturi li jissodisfaw ilkriterji kliniċi għal donazzjoni ta' ċelluli steminali b'attenzjoni partikulari lejn il-parametri ematoloġiċi u mard infettiv.
English: Graft versus Host Disease b
Maltese: Prekawzjonijiet speċjali f'pazjenti b'SCN
English: Continuous infusion with filgrastim over a period of up to 28 days, in patients recovering from autologous bone-marrow transplantation, resulted in no evidence of drug accumulation and comparable elimination half-lives.
Maltese: Waqt infużjoni kontinwa b'filgrastim fuq medda ta' 28 ġurnata, f'pazjenti li kienu qedin jirkupraw minn trapjant awtologu talmudullun, ma kienx hemm xi evidenza t'akkumulazzjoni u l-half-lives ta' eliminazzjoni kienu komparabbli.
English: As a result of the potential to receive higher doses or a greater number of these medications with filgrastim therapy, the patient may be at higher risk of developing thrombocytopenia and anaemia.
Maltese: id-doża sħiħa ta' kimoterapija mijelosoppressiva fl-iskeda preskritta), il-pazjent jista' jkollu riskju ogħla ta' tromboċitopenja u anemija.
English: e
Maltese: MU
English: Another randomised, double-blind, multiple-dose, comparator-controlled, two-way crossover study in 50 healthy volunteers showed that the pharmacokinetic profile of Nivestim was comparable to that of the reference product after subcutaneous administration.
Maltese: Studju każwali, double-blind, inkroċjat fiż-żewġ direzzjonijiet ieħor, li sar b'dożi multipli u li jista' jitqabbel mal-kontroll fuq 50 voluntier b'saħħtu wera li l-profil farmakokinetiku ta' Nivestim kien komparabbli mal-prodott ta' riferiment wara l-għoti taħt il-ġilda.
English: Cases of splenomegaly and splenic rupture have been reported following administration of filgrastim.
Maltese: Infjammazzjoni vaskulari fil-ġilda ġiet osservata f'pazjenti li ngħataw filgrastim.
English: For patients treated with filgrastim diluted to concentrations below 1.5 MU (15 g) per ml, human serum albumin (HSA) should be added to a final concentration of 2 mg/ml.
Maltese: MU (15 µg)/mL, għandha tiġi miżjuda bl-albumina umana (HSA) sabiex il-konċentrazzjoni finali tkun 2 mg/mL.
English: Headache a
Maltese: Wara d-dilwazzjoni
English: Skin and subcutaneous tissue disorders
Maltese: DIKJARAZZJONI TAS-SUSTANZA ATTIVA
English: • Nivestim 48 MU/0.5 ml solution for injection/infusion: each pre-filled syringe contains 48 million units (MU), 480 g of filgrastim in 0.5 ml (corresponding to 0.96 mg/ml).
Maltese: 48 miljun unità (MU), 480 µg ta' filgrastim f'0.5 mL (li jikkorispondi għal 0.96 mg/mL).
English: It is recommended to perform morphologic and cytogenetic bone marrow examinations in patients at regular intervals (approximately every 12 months).
Maltese: Huwa rrakkomandat li jsiru investigazzjonijiet morfoloġiċi u ċitoġeniċi tal-mudullun fil-pazjenti f'intervalli regolari (madwar kull 12-il xahar).
English: • bleeding from the lung (pulmonary haemorrhage)
Maltese: • ħruġ ta' demm mill-pulmun (emorraġija pulmonari)
English: • high uric acid levels in the blood, which may cause gout (hyperuricaemia) (Blood uric acid increased)
Maltese: • livelli għoljin ta' aċidu uriku fid-demm, li jistgħu jikkawżaw gotta (iperurikemija) (Żieda fl aċidu uriku fid-demm)
English: The stem cells will then go back into the bone marrow and produce blood cells; - to increase the number of white blood cells if you suffer from severe chronic neutropenia to help prevent infections; - in patients with advanced HIV infection which will help reduce the risk of infections.
Maltese: Imbagħad, iċ-ċelluli staminali jmorru lura fil-mudullun u jipproduċu ċelluli tad-demm; - sabiex iżid in-numru ta' ċelluli bojod tad-demm jekk tbati minn newtropenija kronika severa sabiex jgħinu fil-prevenzjoni tal-infezzjonijiet; - f'pazjenti b'infezzjoni tal-HIV avvanzata sabiex jgħin fil-prevenzjoni tal-infezzjonijiet.
English: Veno-occlusive disease d
Maltese: IL-PRODOTT MEDIĊINALI
English: If you are a stem cell donor, you must be aged between 16 and 60 years.
Maltese: Jekk inti donatur taċ-ċelluli staminali, irid ikollok bejn 16 u 60 sena.
English: Congenital neutropenia: the recommended starting dose is 1.2 MU (12 µg)/kg/day as a single dose or in divided doses.
Maltese: Id-doża tal-bidu rakkomandata hi 1.2 MU (12 µg)/kg/jum bħala doża waħda jew f'dożi maqsumin.
English: You may notice a small air bubble in the syringe.
Maltese: Aħsel idejk sew bl-ilma u s-sapun.
English: Pre-filled syringe (type I glass), with injection needle (stainless steel) with a needle guard, containing 0.2 ml solution for injection/infusion.
Maltese: Siringa mimlija għal-lest (ħġieġ ta' Tip I) b'labra tal-injezzjoni (stainless steel) bi protezzjoni tal-labra li fiha 0.5 mL soluzzjoni għall-injezzjoni/infużjoni.
English: SYRINGE LABEL
Maltese: TIKKETTA/SIRINGA
English: Donors who receive G-CSFs for PBPC mobilisation should be monitored until haematological indices return to normal.
Maltese: Donaturi li jirċievu kura b'G-CSF għal mobilizzazzjoni ta' PBPC jridu jkunu monitorjati sew sakemm il-parametri ematoloġiċi jerġgħu lura għan-normal.
English: • get left upper belly (abdominal) pain, pain below the left rib cage or at the tip of your left shoulder (these may be symptoms of an enlarged spleen (splenomegaly), or possibly rupture of the spleen).
Maltese: • tinnota emorraġija jew tbenġil mhux tas-soltu (dawn jistgħu jkunu sintomi ta' tnaqqis fil plejtlits tad-demm (tromboċitopenija), bi tnaqqis fil-ħila ta' demmek sabiex jagħqad).
English: There are reports in the literature where the transplacental passage of filgrastim in pregnant women has been demonstrated.
Maltese: L-effetti ta' doża eċċessiva ta' filgrastim ma ġiex stabbilit.
English: • muscle spasm
Maltese: • uġigħ fis-sider
English: Leukapheresis should be performed during the period when the ANC rises from < 0.5 x 10
Maltese: Lewkafereżi jrid isir fil-perijodu meta l-ANC jitla' minn < 0.5 x 10
English: Nivestim 30 MU/0.5 ml solution for injection/infusion, Nivestim 48 MU/0.5 ml solution for injection/infusion
Maltese: • Nivestim 30 MU/0.5 mL soluzzjoni għal injezzjoni/ infużjoni: kull siringa mimlija lesta fiha
English: ATCvet code: QP54AB51 (milbemycin combinations).
Maltese: Kodici ATC veterinarja: QP54AB51 (kombinazzjonijiet ta' milbemycin).
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 19/09/2013
Maltese: DATA TAL-EWWEL AWTORIZZAZZJONI / TIĠDID TAL-AWTORIZZAZZJONI Data tal-ewwel awtorizzazzjoni: 19/09/2013
English: Overdose (symptoms, emergency procedures, antidotes):
Maltese: Doża eċċessiva (sintomi, proċeduri ta' emerġenza, antidoti) :
English: Microcrystalline cellulose Hydroxypropyl cellulose Silica, colloidal anhydrous Croscarmellose sodium Magnesium stearate Artificial beef flavour
Maltese: Microcrystalline cellulose Hydroxypropyl cellulose Silica, colloidal anhydrous Croscarmellose sodium Magnesium stearate Togħma artifiċjali taċ-ċanga
English: Method of administration:
Maltese: Metodu ta' amministrazzjoni
English: Pharmacotherapeutic group: Antiparasitic products, insecticides and repellents - endectocides.
Maltese: Prodotti anti-parassitiċi, insettiċidi u ripellanti - endektoċidi.
English: There is no antidote available.
Maltese: M'hemm l-ebda antidot disponibbli.
English: Approximately 90% of spinosad is comprised of spinosyns A and D. Of that 90%, the ratio of spinosyn A to A+D is 0.85 when calculated as spinosyn A/spinosyn A+D.
Maltese: Minn dawk id-90%, il-proporzjon ta' spinosin A għal A+D hu ta' 0.85 meta kkalkulat bħala spinosin A/spinosin A+D.
English: Manufacturer responsible for batch release: Eli Lilly and Company Ltd Speke Operations
Maltese: Manifattur responsabbli għall-ħruġ tal-lott: Eli Lilly and Company Ltd Speke Operations
English: Dosage:
Maltese: Dożaġġ:
English: Milbemycin oxime is isolated from the fermentation of Streptomyces hygroscopicus var. aureolacrimosus.
Maltese: Milbemycin oxime hu iżolat mill-fermentazzjoni ta' Streptomyces hygroscopicus var. aureolacrimosus.
English: Carton containing 1 blister pack.
Maltese: Kartuna li fiha pakkett bil-blisters.
English: Angiostrongylus vasorum, - treatment of gastrointestinal nematode infections caused by hookworm (L4, immature adult (L5)
Maltese: Angiostrongylus vasorum, - kura ta' infezzjonijiet b'nematodi gastrointestinali kkawżati minn hookworm (L4, adult immaturi
English: Speke Operations Fleming Road Liverpool
Maltese: Eli Lilly and Company Ltd Speke Operations Fleming Road Liverpool
English: The primary faecal and urinary metabolites in dog were identified as glucuronide conjugates of milbemycin A3 or A4 5-oximes, dealkylated milbemycin A3 or A4 5-oximes, and hydroxylated milbemycin A4 5-oxime.
Maltese: Il-metaboliti primarji fl-ippurgar u urinarji fil-klieb ġew identifikati bħala konjugati glucuronide ta' milbemycin A3 jew A4 5-oximes, dealkylated milbemycin A3 jew A4 5-oximes, u hydroxylated milbemycin A4 5-oxime.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Active substances:
Maltese: U KWANTITATTIVA Sustanzi Attivi:
English: Trifexis 1620 mg/27 mg tablets:
Maltese: Trifexis 1620 mg/27 mg pilloli:
English: Spinosad starts killing fleas 30 minutes after administration; 100% of fleas are dead/moribund within 4 hours post-treatment.
Maltese: Spinosad jibda joqtol il-briegħed 30 minuta wara lgħoti; 100% tal-briegħed ikunu mejtin/moribondi fi żmien 4 sigħat wara l-kura.
English: Cmax was comparable between juveniles and adults starting at month 1, indicating no increased risk of acute toxicity.
Maltese: Is-Cmax kien komparabbli bejn klieb ġuvenili u klieb adulti, u dan beda f'xahar 1, li ma jindika l-ebda riskju miżjud ta' tossiċità akuta.
English: 4349 and 4 dimples
Maltese: 4349 u 4 ħofor żgħar
English: These effects are caused primarily by activation of nicotinic acetylcholine receptors (nAChRs).
Maltese: Dawn l-effetti huma kkawżati primarjament mill-attivazzjoni ta' riċetturi acetylcholine nikotiniċi (nAChRs).
English: Accurate dosing is not possible in dogs weighing less than 3.9 kg.
Maltese: Dożaġġ preċiż mhuwiex possibbli fi klieb li jiżnu inqas minn 3.9 kg.
English: Trifexis 665 mg/11.1 mg tablets:
Maltese: Trifexis 665 mg/11.1 mg pilloli:
English: At three times the maximum recommended dose adverse events of potentially neurological origin e.g. decreased activity (8%), hypersalivation (17%) or stumbling (8%) were observed.
Maltese: Bi tliet darbiet id-doża massima rakkomandata, avvenimenti avversi ta' oriġini potenzjalment newroloġika eż. tnaqqis fl-attività (8%), tbeżliq eċċessiv (17%) jew li l-kelb jitfixkel f'saqajh (8%) ġew osservati.
English: The mean Tmax for spinosyns A and D was 4 hours and the mean elimination half-lives ranged between 131 and 135 hours.
Maltese: Il-medja tat-Tmass għal spinosyns A u D kienet ta' 4 sigħat u l-medja tal-half lives tal-eliminazzjoni varjat bejn 131 u 135 siegħa.
English: Milbemycin oxime, like avermectins and other milbemycins, increases nematode and insect membrane permeability to chloride ions via glutamate-gated chloride ion channels (related to vertebrate GABA and glycine receptors).
Maltese: Milbemycin oxime, bħal avermectins u milbemycins oħrajn, iżid ilpermeabilità tal-membrana tan-nematodi u tal-insetti għal joni tal-chloride permezz tal-kanali glutamate-gated chloride ion (relatati ma' vertebrati
English: and adult Ancylostoma caninum), roundworms (immature adult L5, and adult Toxocara canis and adult Toxascaris leonina) and whipworm (adult Trichuris vulpis).
Maltese: Angiostrongylus vasorum, - kura ta' infezzjonijiet b'nematodi gastrointestinali kkawżati minn hookworm (L4, adult immaturi (L5) u Ancylostoma caninum adulti, roundworms (L5 adulti immaturi, u Toxocara canis adulti u Toxascaris leonina adulti) u whipworm (Trichuris vulpis adulti).
English: The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment) - common (more than 1 but less than 10 animals in 100 animals) - uncommon (more than 1 but less than 10 animals in 1,000 animals) - rare (more than 1 but less than 10 animals in 10,000 animals) - very rare (less than 1 animal in 10,000 animals, including isolated reports).
Maltese: Il-frekwenza ta' effetti mhux mixtieqa hija definita skont din il-konvenzjoni: - komuni ħafna (aktar minn wieħed f'10 annimali li juru effetti mhux mixtieqa matul il-perjodu ta' kura waħda) - komuni (aktar minn wieħed iżda inqas minn 10 annimali f'100 annimal) - mhux komuni (aktar minn wieħed iżda inqas minn10 annimali f'1,000 annimal) - rari (aktar minn wieħed iżda inqas minn10 annimali f'10,000 annimal) - rari ħafna (inqas minn annimal wieħed f'10,000 annimal, inklużi rapporti iżolati).
English: In case of adverse clinical signs, treat symptomatically.
Maltese: F'każ ta' sinjali kliniċi avversi, ikkura b'mod sintomatiku.
English: Milbemycin oxime is an antiparasitic endectocide belonging to the macrocyclic lactones.
Maltese: Milbemycin oxime hu endektoċida kontra l-parassiti li jappartjeni għal lactones makroċikliċi.
English: Trifexis 1040 mg/17.4 mg tablets:
Maltese: Trifexis 1040 mg/17.4 mg pilloli:
English: 4336 and 5 dimples
Maltese: 4336 u 5 ħofor żgħar
English: In rats dosed with milbemycin A4 5-oxime, the main metabolites identified in urine and faeces were mono-, di-, and trihydroxy milbemycin A4 5-oximes.
Maltese: F'firien li ngħataw dożi b'milbemycin A4 5-oxime, il-metaboliti prinċipali identifikati fl-awrina u fl-ippurgar kienu mono-, di-, u trihydroxy milbemycin A4 5-oximes.
English: Trifexis 425 mg/7.1 mg tablets:
Maltese: Trifexis 425 mg/7.1 mg pilloli:
English: A single treatment is effective for the treatment of gastrointestinal nematodes.
Maltese: Trattament wieħed hu effettiv għall-kura ta' nematodi gastrointestinali.
English: Milbemycin oxime is a systemic macrocyclic lactone containing two major factors, A3 and A4 (ratio of A3:A4 is 20:80).
Maltese: Milbemycin oxime hu lactone makroċikliku sistemiku li fih żewġ fatturi maġġuri, A3 u A4 (ilproporzjon ta' A3:A4 hu ta' 20:
English: The mean Tmax for milbemycin A3 and A4 5-oximes was typically 4 hours and the mean elimination half-lives were 33.9 and 77.2 hours.
Maltese: Il-medja tat-Tmass għal milbemycin A3 u A4 5oximes kienet tipikament 4 sigħat u l-medja tal-half lives tal-eliminazzjoni kienet ta' 33.9 u 77.2 sigħat.
English: In studies performed with spinosad only, the primary biliary, faecal and urinary metabolites in both rat and dog were identified as the demethylated spinosyns, glutathione conjugates of the parent compounds and N-demethylated spinosyns A and D. Excretion is primarily via the bile and faeces, and to a lesser extent in the urine.
Maltese: Fi studji li twettqu bi spinosad biss, il-metaboliti primarji tal-marrara, fl-ippurgar u urinarji, kemm filfirien kif ukoll fil-klieb, ġew identifikati bħala demethylated spinosyns, konjugati glutathione talkomposti ġenituri u N-demethylated spinosyns A u D.
English: Trifexis 270 mg/4.5 mg tablets:
Maltese: Trifexis 270 mg/4.5 mg pilloli:
English: Plasma protein binding is high (>96%).
Maltese: It-twaħħil tal-proteini fil-plażma hu għoli (>96%).
English: 4333 and 2 dimples
Maltese: 4333 u 2 ħofor żgħar
English: METHOD AND ROUTE(S) OF ADMINISTRATION Administer with food.
Maltese: METODU U MOD(I) TA' AMMINISTRAZZJONI Agħtih mal-ikel.