FrancophonIA/ELRC3.0 huggingface dataset:
English: The HALDOL 2 mg/ml oral solution in a dropper container is intended to be used for single doses up to 2 mg haloperidol (equivalent to 20 drops).
Croatian: HALDOL 2 mg/ml oralna otopina u spremniku s kapaljkom namijenjena je za primjenu pojedinačnih doza haloperidola do 2 mg (što odgovara 20 kapi).
English: • The amount of Haldol you take will then be adjusted until the doctor finds the dose that suits you best.
Croatian: • Nakon toga će liječnik prilagođavati količinu lijeka Haldol dok ne pronađe dozu koja Vam najbolje odgovara.
English: ECG monitoring is recommended up to 6 hours after administration of HALDOL solution for injection to patients for prophylaxis or treatment of postoperative nausea and vomiting.
Croatian: preporučuje se EKG praćenje u trajanju do 6 sati nakon primjene HALDOL otopine za injekciju.
English: • Combination treatment of postoperative nausea and vomiting when other medicinal products are ineffective or not tolerated.
Croatian: • kombinirano liječenje poslijeoperacijske mučnine i povraćanja kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi.
English: It may be combined with antidepressants to treat those conditions in which depression and psychosis coexist (see section 4.5).
Croatian: Može se kombinirati s antidepresivima za liječenje stanja kod kojih su istodobno prisutne depresija i psihoza
English: Treatment of acute psychomotor agitation associated with psychotic disorder or manic episodes of bipolar I disorder
Croatian: Liječenje akutne psihomotoričke agitacije povezane sa psihotičnim poremećajem ili maničnim epizodama bipolarnog poremećaja tipa
English: The HALDOL 10 mg/ml oral solution in a dropper container is intended to be used for single doses up to 10 mg haloperidol (20 drops).
Croatian: HALDOL 10 mg/ml oralna otopina u spremniku s kapaljkom namijenjena je za primjenu pojedinačnih doza haloperidola do 10 mg (20 kapi).
English: 10 mg/ml oral solution:
Croatian: 10 mg/ml oralna otopina:
English: • 2 to 10 mg/day orally, as a single dose or in 2 divided doses.
Croatian: • 2 - 10 mg na dan peroralno, kao jedna doza ili podijeljeno na 2 doze.
English: • It is recommended to assess the individual benefit-risk when considering doses above 3 mg/day.
Croatian: • Kada se razmatraju doze veće od 3 mg na dan, preporučuje se ocijeniti omjer koristi i rizika za pojedinog bolesnika.
English: • 1 to 2 mg intramuscularly.
Croatian: • 1 - 2 mg intramuskularno.
English: the number of millilitres (ml) is just visible (figure 2).
Croatian: Nastavite ga povlačiti dok ne ugledate oznaku koja odgovara broju mililitara (ml) (slika 2).
English: The dose recommendations for HALDOL tablets are presented in Table 4.
Croatian: Preporučene doze za HALDOL tablete navedene su u Tablici 4.
English: Combination treatment of postoperative nausea and vomiting when other medicinal products are ineffective or not tolerated
Croatian: Kombinirano liječenje poslijeoperacijske mučnine i povraćanja kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi
English: Treatment of moderate to severe manic episodes associated with bipolar I disorder
Croatian: Liječenje umjerenih do teških maničnih epizoda povezanih s bipolarnim poremećajem tipa
English: The dose recommendations for HALDOL tablets are presented in Table 1.
Croatian: Preporučene doze za HALDOL tablete navedene su u Tablici 1.
English: 6 drops
Croatian: 6 kapi
English: • Constipation
Croatian: • pospanost
English: • Treatment of persistent aggression and psychotic symptoms in patients with moderate to severe Alzheimer's dementia and vascular dementia when non-pharmacological treatments have failed and when there is a risk of harm to self or others.
Croatian: • Liječenje dugotrajne agresije i psihotičnih simptoma u bolesnika s umjerenom do teškom Alzheimerovom demencijom i vaskularnom demencijom kada su nefarmakološka liječenja neuspješna i kada postoji rizik od samoozljeđivanja ili ozljeđivanja drugih osoba - 0,5 mg na dan.
English: Treatment of mild to moderate chorea in Huntington's disease, when other medicinal products are ineffective or not tolerated, and oral therapy is not appropriate
Croatian: Liječenje blage do umjerene koreje kod Huntingtonove bolesti kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi i kada peroralna terapija nije prikladna
English: Treatment of tic disorders, including Tourette's syndrome, in patients with severe impairment after educational, psychological and other pharmacological treatments have failed
Croatian: Liječenje poremećaja s tikovima, uključujući Touretteov sindrom, u bolesnika s teškim oštećenjem nakon neuspjeha edukacijskih, psiholoških i drugih farmakoloških terapija
English: 2 drops
Croatian: 2 kapi
English: The HALDOL 2 mg/ml oral solution in a bottle with an oral syringe is intended to be used for single doses of 0.5 mg haloperidol and above (equivalent to 0.25 ml and above).
Croatian: HALDOL 2 mg/ml oralna otopina u boci sa štrcaljkom za usta namijenjena je za primjenu pojedinačnih doza haloperidola od 0,5 mg ili više (što odgovara 0,25 ml ili više).
English: • The dose will then be adjusted until the doctor finds the dose that suits you best.
Croatian: • Nakon toga će liječnik prilagođavati dozu dok ne pronađe onu koja Vam najbolje odgovara.
English: • Treatment of acute psychomotor agitation associated with psychotic disorder or manic episodes of bipolar I disorder.
Croatian: • Liječenje akutne psihomotoričke agitacije povezane s psihotičnim poremećajem ili maničnim epizodama bipolarnog poremećaja tipa I.
English: 4 drops
Croatian: 4 kapi
English: Musculoskeletal and connective tissue disorders
Croatian: Poremećaji mišićno koštanog sustava i vezivnog tkiva tortikolis,
English: • Psychoses (such as fluphenazine, levomepromazine, perphenazine, pimozide, prochlorperazine,
Croatian: • psihoze (kao što su flufenazin, levomepromazin, perfenazin, pimozid, proklorperazin, promazin, sertindol, tiorizadin, trifluoperazin, triflupromazin i ziprazidon)
English: • Treatment of mild to moderate chorea in Huntington's disease, when other medicinal products are ineffective or not tolerated, and oral therapy is not appropriate.
Croatian: • liječenje blage do umjerene koreje kod Huntingtonove bolesti kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi i kada peroralna terapija nije prikladna.
English: • The recommended dose is 0.5 to 3 mg/day, administered orally in divided doses (2 to 3 times a day).
Croatian: • Preporučena doza je 0,5 - 3 mg na dan, a primjenjuje se peroralno, podijeljena na više doza
English: Package Leaflet for 10 mg/ml oral solution - bottle with oral syringe only:
Croatian: Uputa o lijeku za 10 mg/ml oralnu otopinu - samo boca sa štrcaljkom za usta:
English: Loss of libido Libido decreased Restlessness
Croatian: depresija stanje konfuzije gubitak libida smanjen libido nemir
English: • The number of tablets you take will then be adjusted until the doctor finds the dose that suits you best.
Croatian: • Nakon toga će liječnik prilagođavati broj tableta dok ne pronađe dozu koja Vam najbolje odgovara.
English: The HALDOL 10 mg/ml oral solution in a bottle with an oral syringe is intended to be used for single doses of 5 mg haloperidol and above (equivalent to 0.5 ml and above).
Croatian: HALDOL 10 mg/ml oralna otopina u boci sa štrcaljkom za usta namijenjena je za primjenu pojedinačnih doza haloperidola od 5 mg ili više (što odgovara 0,5 ml ili više).
English: • Screw the oral syringe onto the bottle.
Croatian: • Navijte štrcaljku za usta na bocu.
English: • 1 to 10 mg/day orally, as a single dose or in 2 to 3 divided doses.
Croatian: • 1 - 10 mg na dan peroralno, u jednoj dozi ili podijeljeno na 2 - 3 doze.
English: 3 drops
Croatian: 3 kapi
English: • Treatment of moderate to severe manic episodes associated with bipolar I disorder.
Croatian: • Liječenje umjerenih do teških maničnih epizoda povezanih s bipolarnim poremećajem tipa I.
English: Package Leaflet for 2 mg/ml oral solution - bottle with oral syringe only:
Croatian: Uputa o lijeku za 2 mg/ml oralnu otopinu - samo boca sa štrcaljkom za usta:
English: As haloperidol is metabolised by the liver, half the initial dose and caution is advised in patients with hepatic impairment (see sections 4.2 and 5.2).
Croatian: Budući da se haloperidol metabolizira u jetri, u bolesnika s oštećenjem jetrene funkcije preporučuje se prepoloviti početnu dozu i primjenjivati lijek uz oprez (vidjeti dijelove 4.2 i 5.2).
English: Heart problems are uncommon in people taking Haldol (may affect up to 1 in 100 people).
Croatian: Srčane tegobe nisu česte kod osoba koje uzimaju Haldol (mogu se javiti u do 1 na 100 osoba).
English: The terminal elimination half-life of haloperidol is on average 24 hours (range of means 15 to 37 hours) after oral administration.
Croatian: Prosječno terminalno poluvrijeme eliminacije haloperidola nakon peroralne primjene iznosi 24 sata
English: • The recommended doses are 0.5 to 3 mg/day in children and adolescents aged 10 to 17 years,
Croatian: • Preporučene doze su 0,5 - 3 mg na dan za djecu i adolescente u dobi od 10 do 17 godina, a primjenjuju se peroralno, podijeljene na više doza (2 - 3 puta na dan).
English: Side effects, such as feeling sleepy, may affect your alertness, particularly when you first start taking it or after a high dose.
Croatian: Vas učiniti manje pozornima, osobito kada tek počnete primati lijek ili nakon velike doze.
English: Table 3: Conversion table for HALDOL 10 mg/ml oral solution mg haloperidol Number of drops of HALDOL (dropper container)
Croatian: Tablica 3: Tablica za pretvorbu doze za HALDOL 10 mg/ml oralnu otopinu mg haloperidola Broj kapi lijeka HALDOL (spremnik s kapaljkom)
English: • Treatment of mild to moderate chorea in Huntington's disease, when other medicinal products are ineffective or not tolerated.
Croatian: • Liječenje blage do umjerene koreje kod Huntingtonove bolesti kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi.
English: Treatment of mild to moderate chorea in Huntington's disease, when other medicinal products are ineffective or not tolerated
Croatian: Liječenje blage do umjerene koreje kod Huntingtonove bolesti kada drugi lijekovi nisu učinkoviti ili ih bolesnik ne podnosi
English: How to store Haldol
Croatian: Kako primjenjivati Haldol
English: In addition, the safety of haloperidol decanoate was evaluated in 410 patients who participated in 3 comparator studies (1 comparing haloperidol decanoate versus fluphenazine and 2 comparing the decanoate formulation to oral haloperidol), 9 open label studies and 1 dose response study.
Croatian: 2 s oralnom formulacijom haloperidola), 9 otvorenih ispitivanja i 1 ispitivanju odgovora na dozu.
English: PHARMACEUTICAL FORM AND CONTENTS Oral solution [To be completed nationally]
Croatian: 14. NAČIN IZDAVANJA LIJEKA [Ispunjava država članica]
English: Angioedema Dermatitis exfoliative Leukocytoclastic vasculitis
Croatian: Poremećaji kože i potkožnog tkiva osip reakcija fotoosjetljivosti urtikarija pruritus hiperhidroza angioedem, eksfolijacijski dermatitis leukocitoklastični vaskulitis
English: • When switching from haloperidol intramuscular injection, HALDOL orally should be initiated at a 1:1 dose conversion rate followed by dose adjustment according to clinical response.
Croatian: potrebno je uvesti uz pretvorbu doze u omjeru 1:1, a zatim prilagođavati dozu u skladu s kliničkim odgovorom.
English: telithromycin).
Croatian: Oralna otopina.
English: • Depression, or you have bipolar disorder and start to feel depressed.
Croatian: • ako bolujete od depresije ili imate bipolarni poremećaj i počnete se osjećati depresivno Možda će Vas trebati pažljivije pratiti i prilagoditi količinu lijeka Haldol koju uzimate.
English: Blood and lymphatic system disorders
Croatian: Poremećaji krvi i limfnog sustava leukopenija pancitopenija agranulocitoza trombocitopenija neutropenija
English: Cholestasis
Croatian: Dojenje
English: The quantity (ml) required to achieve a given single dose using HALDOL 10 mg/ml oral solution is presented below.
Croatian: Količina (ml) potrebna za postizanje odgovarajuće pojedinačne doze kada se koristi HALDOL 10 mg/ml oralna otopina navedeni su u nastavku.
English: • Remove the cap from the bottle by pushing down on the cap while turning it anti-clockwise.
Croatian: • Skinite čep s boce tako da ga pritisnete prema dolje i okrenete u smjeru suprotnom od kazaljke na satu.
English: The quantity (ml) required to achieve a given single dose using HALDOL 2 mg/ml oral solution is presented below.
Croatian: Količina (ml) potrebna za postizanje odgovarajuće pojedinačne doze kada se koristi HALDOL 2 mg/ml oralna otopina navedeni su u nastavku.
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 20 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 20 mg tablete
English: The dose recommendations for HALDOL oral solution are presented in Table 4.
Croatian: Preporučene doze za HALDOL oralnu otopinu navedene su u Tablici 4.
English: HALDOL and associated names (see Annex I) 2 mg/ml oral solution HALDOL and associated names (see Annex I) 10 mg/ml oral solution
Croatian: Uputa o lijeku: Informacije za bolesnika HALDOL i pridružena imena (vidjeti Prilog I.) 2 mg/ml oralna otopina HALDOL i pridružena imena (vidjeti Prilog I.) 10 mg/ml oralna otopina
English: Conversion table for HALDOL 10 mg/ml oral solution mg haloperidol ml HALDOL (bottle with oral syringe)
Croatian: Tablica za pretvorbu doze za HALDOL 10 mg/ml oralnu otopinu mg haloperidola ml lijeka HALDOL (boca sa štrcaljkom za usta)
English: • From postmarketing experience with haloperidol and haloperidol decanoate.
Croatian: • nuspojave haloperidola i haloperidoldekanoata prijavljene nakon stavljanja lijeka u promet
English: The individual benefit-risk should be assessed when considering doses above 10 mg/day.
Croatian: Kada se razmatraju doze veće od 10 mg na dan, potrebno je ocijeniti omjer koristi i rizika za pojedinog bolesnika.
English: Conversion table for HALDOL 2 mg/ml oral solution mg haloperidol ml HALDOL (bottle with oral syringe)
Croatian: Tablica za pretvorbu doze za HALDOL 2 mg/ml oralnu otopinu mg haloperidola ml lijeka HALDOL (boca sa štrcaljkom za usta)
English: The number of drops required to achieve a given single dose using HALDOL 10 mg/ml oral solution is presented below.
Croatian: Broj kapi potrebnih za postizanje odgovarajuće pojedinačne doze kada se koristi HALDOL 10 mg/ml oralna otopina navedeni su u nastavku.
English: Cardiac arrest (the heart stops beating) has also occurred in people taking antipsychotic medicines.
Croatian: U bolesnika liječenih antipsihoticima zabilježeni su i slučajevi srčanog zastoja
English: It is rare in people using Haldol (may affect up to 1 in 1,000 people).
Croatian: Haldol (može se javiti u do 1 na 1000 osoba).
English: How Haldol is given
Croatian: Kako se Haldol primjenjuje
English: Taking Haldol
Croatian: Uzimanje lijeka Haldol
English: • High level of the hormone ‘prolactin' in the blood
Croatian: Rijetke (mogu se javiti u do 1 na 1000 osoba): • visoka razina hormona ‘prolaktina' u krvi
English: The possible increase in intraocular pressure must be considered when anticholinergic medicinal products, including antiparkinson medicinal products, are administered concomitantly with HALDOL.
Croatian: uključujući antiparkinsonike, mora se uzeti u obzir mogući porast intraokularnog tlaka.
English: Your doctor may have to change your dose of Haldol if you are taking any of these medicines.
Croatian: Ako uzimate neki od navedenih lijekova, Vaš će liječnik možda morati promijeniti dozu lijeka
English: • Weight gain or loss
Croatian: • povećanje ili smanjenje tjelesne težine
English: The dose recommendations for HALDOL oral solution are presented in Table 1.
Croatian: Preporučene doze za HALDOL oralnu otopinu navedene su u Tablici 1.
English: Treatment of schizophrenia in adolescents aged 13 to 17 years when other pharmacological treatments have failed or are not tolerated
Croatian: Tablica 4: Preporučene doze haloperidola za pedijatrijsku populaciju Liječenje shizofrenije u adolescenata u dobi od 13 do 17 godina kada je liječenje drugim lijekovima neuspješno ili ih bolesnik ne podnosi
English: Therefore, half the initial dose and caution is advised in patients with hepatic impairment (see sections 4.2 and 4.4).
Croatian: Stoga se u bolesnika s oštećenjem jetrene funkcije preporučuje prepoloviti početnu dozu i primjenjivati lijek uz oprez (vidjeti dijelove 4.2 i 4.4).
English: Table 2: Conversion table for HALDOL 2 mg/ml oral solution mg haloperidol Number of drops of HALDOL (dropper container)
Croatian: Tablica za pretvorbu doze za HALDOL 2 mg/ml oralnu otopinu mg haloperidola Broj kapi lijeka HALDOL (spremnik s kapaljkom)
English: Dyspnoea
Croatian: Nuspojava
English: Package Leaflet for 2 mg/ml oral solution - dropper container only:
Croatian: Uputa o lijeku za 2 mg/ml oralnu otopinu - samo spremnik s kapaljkom:
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 4 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 4 mg tablete
English: Tardive dyskinesia Akathisia Bradykinesia Dyskinesia Dystonia Hypokinesia Hypertonia Dizziness Somnolence Tremor
Croatian: Poremećaji živčanog sustava ekstrapiramid ni poremećaj hiperkinezija glavobolja tardivna diskinezija akatizija bradikinezija diskinezija distonija hipokinezija, hipertonija omaglica somnolencija tremor konvulzije parkinsonizam sedacija nevoljne mišićne kontrakcije neuroleptički maligni sindrom motorička disfunkcija nistagmus akinezija fenomen „zupčaste ukočenosti“ (eng.
English: The number of drops required to achieve a given single dose using HALDOL 2 mg/ml oral solution is presented below.
Croatian: Broj kapi potrebnih za postizanje odgovarajuće pojedinačne doze kada se koristi HALDOL 2 mg/ml oralna otopina navodi se u nastavku.
English: • Rapid control of severe acute psychomotor agitation associated with psychotic disorder or manic episodes of bipolar I disorder when oral therapy is not appropriate.
Croatian: • brzu kontrolu teške akutne psihomotoričke agitacije povezane s psihotičnim poremećajem ili maničnim epizodama bipolarnog poremećaja tipa
English: Package Leaflet for 10 mg/ml oral solution - dropper container only:
Croatian: Uputa o lijeku za 10 mg/ml oralnu otopinu - samo spremnik s kapaljkom:
English: • Empty the contents onto a spoon.
Croatian: • Ispraznite sadržaj u žlicu.
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 5 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 5 mg tablete
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 1 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 1 mg tablete
English: Psychotic disorder Depression
Croatian: Psihijatrijski poremećaji agitacija nesanica psihotični poremećaj,
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 10 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 10 mg tablete
English: Tablet [To be completed nationally]
Croatian: Pomoćna tvar [Ispunjava država članica]
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 2 mg tablets [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 2 mg tablete
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 2 mg/ml oral solution [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 2 mg/ml oralna otopina
English: You may need to be more closely monitored, and the amount of Haldol you are given may have to be altered.
Croatian: • ako bolujete od depresije ili imate bipolarni poremećaj i počnete se osjećati depresivno Možda će Vas trebati pažljivije pratiti i prilagoditi količinu lijeka Haldol koju primate.
English: NAME OF THE MEDICINAL PRODUCT HALDOL and associated names (see Annex I) 10 mg/ml oral solution [See Annex I - To be completed nationally] haloperidol
Croatian: NAZIV LIJEKA HALDOL i pridružena imena (vidjeti Prilog I.) 10 mg/ml oralna otopina
English: An allergic reaction is uncommon in people using Haldol (may affect up to 1 in 100 people).
Croatian: Srčane tegobe nisu česte kod osoba koje primaju Haldol (mogu se javiti u do 1 na 100 osoba).
English: Table 4: Haloperidol dose recommendations for paediatric population
Croatian: Tablici 2 navode se sljedeće nuspojave: • nuspojave prijavljene u kliničkim ispitivanjima haloperidola
English: • Being short of breath
Croatian: • nedostatak zraka
English: Agitation Insomnia
Croatian: Nuspojave poput pospanosti mogu
English: administered orally in divided doses (2 to 3 times a day).
Croatian: (2 - 3 puta na dan).
English: Tardive dyskinesia
Croatian: ROK VALJANOSTI
English: 20 drops Package Leaflet for 2 mg/ml oral solution - bottle with oral syringe only:
Croatian: 10 ml Uputa o lijeku za 10 mg/ml oralnu otopinu - samo spremnik s kapaljkom:
English: In addition, there was no reason why the medicine would work in one group of patients and not in others.
Croatian: Osim toga, nije bilo razloga zašto bi lijek djelovao u jednoj skupini bolesnika, ali ne i kod drugih.
English: It had requested a re-examination of the opinion but later withdrew its request.
Croatian: Tvrtka je zatražila preispitivanja prvotnog mišljenja, ali kasnije je povukla zahtjev.
English: Furthermore, an inspection at two of the study sites showed deficiencies in the way the study was conducted, which cast doubt on the integrity of the data.
Croatian: Nadalje, inspekcija na dvjema lokacijama ispitivanja pokazala je nedostatke u načinu na koji se vodilo ispitivanje, što je stvorilo sumnju u pogledu cjelovitosti podataka.
English: What is Alsitek?
Croatian: Što je Alsitek?
English: Refusal of the marketing authorisation for Alsitek (masitinib) EMA/207380/2018
Croatian: Odbijanje odobrenja za stavljanje u promet lijeka Alsitek (masitinib) EMA/207380/2018
English: Although a positive effect on symptoms was seen in the group of patients whose disease worsened at a normal rate compared with those whose disease worsened rapidly, the CHMP considered that this way of classifying patients was arbitrary and did not reflect clinical practice.
Croatian: Iako je pozitivan učinak na simptome uočen u skupini bolesnika čija se bolest pogoršavala uobičajenom brzinom u odnosu na bolesnike čija je bolest brzo napredovala, CHMP je smatrao da je taj način razvrstavanja bolesnika proizvoljan i ne odražava kliničku praksu.
English: The main measure of effectiveness was the change in the patients' symptoms after 48 weeks of treatment, assessed using a standard scale for ALS.
Croatian: Glavno mjerilo djelotvornosti bila promjena simptoma u bolesnika nakon 48 tjedana, koja je procijenjena na temelju standardne ljestvice za ALS.
English: ALS is a progressive disease of the nervous system, where nerve cells in the brain and spinal cord that control voluntary movement gradually deteriorate, causing loss of muscle function and paralysis.
Croatian: ALS je progresivna bolest živčanog sustava kod koje živčane stanice u mozgu i leđnoj moždini koje kontroliraju dobrovoljno kretanje postupno odumiru, uzrokujući gubitak mišićne funkcije i paralizu.
English: By reducing their activity, the medicine is expected to reduce inflammation and damage to nerves, thereby slowing down the worsening of the patient's symptoms.
Croatian: Očekuje se da će lijek smanjivanjem njihove aktivnosti smanjiti upalu i oštećenje živaca, čime će usporiti pogoršavanje bolesnikovih simptoma.
English: Alsitek is thought to work by reducing the activity of microglia, the main immune (defence) cells of the brain, and mast cells, a type of white blood cell.
Croatian: Smatra se da Alsitek djeluje na način da smanjuje aktivnost stanica mikroglije, koje su glavne (obrambene) stanice mozga, i mastocita, vrste bijelih krvnih stanica.