FrancophonIA/ELRC3.0 huggingface dataset:
English: Pegfilgrastim and filgrastim have been shown to have identical modes of action, causing a marked increase in peripheral blood neutrophil counts within 24 hours, with minor increases in monocytes and/or lymphocytes.
Slovenian: Dokazali so, da imata pegfilgrastim in filgrastim enak način delovanja, v 24 urah povzročita izrazito zvišanje števila nevtrofilcev v periferni krvi, medtem ko je zvišanje monocitov in/ali limfocitov manjše.
English: The on-body injector is working properly.
Slovenian: Injektor deluje pravilno.
English: Do not use the pre-filled syringe if it has been dropped on a hard surface.
Slovenian: Ne uporabite napolnjene injekcijske brizge, če je ta pred tem padla na trdo površino.
English: In the absence of growth factor support, this regimen has been reported to result in a mean duration of grade 4 neutropenia of 5 to 7 days, and a 30-40% incidence of febrile neutropenia.
Slovenian: Poročajo, da je ta odmerna shema v odsotnosti podpore s strani rastnega faktorja povzročila nevtropenijo 4. stopnje, ki je povprečno trajala 5 do 7 dni, in 30-40 % incidenco febrilne nevtropenije.
English: Turn the plunger to move the label into a position where you can remove the syringe label.
Slovenian: Obrnite bat tako, da nalepko premaknete na mesto, s katerega jo boste lahko odstranili.
English: SCIENTIFIC CONCLUSIONS AND GROUNDS FOR THE VARIATION TO THE TERMS OF THE MARKETING AUTHORISATION(S)
Slovenian: ZNANSTVENI ZAKLJUČKI IN PODLAGA ZA SPREMEMBO POGOJEV DOVOLJENJA (DOVOLJENJ) ZA PROMET Z ZDRAVILOM
English: • damage to the tiny filters inside your kidneys (glomerulonephritis).
Slovenian: • okvara drobnih filtrov v ledvicah (glomerulonefritis).
English: • Do not expose the on-body injector to direct sunlight.
Slovenian: • Injektorja ne izpostavljajte neposredni sončni svetlobi.
English: Amgen NV Telecomlaan 5-7 1831 Diegem Belgium
Slovenian: Amgen NV Telecomlaan 5-7 1831 Diegem Belgija
English: Pegfilgrastim is a covalent conjugate of recombinant human G-CSF (r-metHuG-CSF) with a single 20 kd polyethylene glycol (PEG) molecule.
Slovenian: Pegfilgrastim je kovalenten konjugat rekombinantnega človeškega G-CSF (r-metHuG-CSF) z eno samo molekulo 20kd polietilenglikola (PEG).
English: In animal models concomitant administration of Neulasta and 5-fluorouracil (5-FU) or other antimetabolites has been shown to potentiate myelosuppression.
Slovenian: Pokazali so, da v živalskih modelih sočasna uporaba zdravila Neulasta in 5-fluorouracila (5-FU) ali drugih antimetabolitov okrepi mielosupresijo.
English: In such circumstances pegfilgrastim should be discontinued at the discretion of the physician and the appropriate treatment given (see section 4.8).
Slovenian: V takih primerih je treba pegfilgrastim po presoji zdravnika prenehati dajati in poskrbeti za ustrezno zdravljenje (glejte poglavje 4.8).
English: The onset of pulmonary signs such as cough, fever, and dyspnoea in association with radiological signs of pulmonary infiltrates, and deterioration in pulmonary function along with increased neutrophil count may be preliminary signs of Acute Respiratory Distress Syndrome (ARDS).
Slovenian: Pojav pljučnih znakov, kot so kašelj, zvišana telesna temperatura in dispneja v povezavi z radiološkimi znaki pljučnih infiltratov, in poslabšanje pljučne funkcije skupaj z zvečanim številom nevtrofilcev utegnejo biti preliminarni znaki sindroma akutne dihalne stiske (ARDS - 'Acute Respiratory Distress Syndrome').
English: It must be a clear and colourless liquid.
Slovenian: Biti mora bistra in brezbarvna tekočina.
English: The safety and efficacy of pegfilgrastim have not been investigated in patients receiving high dose chemotherapy.
Slovenian: Varnosti in učinkovitosti pegfilgrastima niso raziskovali pri bolnikih, ki prejemajo kemoterapijo v velikih odmerkih.
English: • It is important that you do not try to give yourself the injection unless you have received training from your doctor or healthcare provider.
Slovenian: • Pomembno je, da si injekcij ne poskušate dajati sami, dokler vas tega ne nauči zdravnik ali zdravstveni delavec.
English: • Stevens-Johnson syndrome, which can appear as reddish target-like or circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals and eyes and can be preceded by fever and flu-like symptoms.
Slovenian: • Stevens-Johnsonov sindrom, ki se lahko pojavi kot rdečkaste lise v obliki tarče ali krožne lise na trupu, pogosto z mehurčki na sredini, luščenje kože, razjede v ustih, grlu, nosu, genitalijah in očeh, pred tem pa se lahko pojavijo vročina in gripi podobni simptomi.
English: There is a small cannula which sits just under your skin.
Slovenian: Tik pod kožo imate drobno kanilo.
English: Step 4: Finish A Discard the used pre-filled syringe and other supplies in a sharps disposal container.
Slovenian: 4. korak: Zaključek A Zavrzite uporabljeno injekcijsko brizgo in drugo opremo v vsebnik za ostre odpadke.
English: 4.7 Effects on ability to drive and use machines
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev
English: • if you are aware of any altered blood cell counts (e.g. increase in white blood cells or anaemia) or decreased blood platelet counts, which reduces the ability of your blood to clot (thrombocytopenia).
Slovenian: • če ste seznanjeni z morebitnimi spremembami števila krvnih celic (npr. s povečanjem števila belih krvničk ali anemijo) ali z zmanjšanim številom krvnih ploščic v krvi, kar zmanjša sposobnost strjevanja krvi (trombocitopenija).
English: Approximately 27 hours after the on-body injector is applied to the patient's skin, Neulasta will be delivered over approximately 45 minutes.
Slovenian: Približno 27 ur po namestitvi injektorja na bolnikovo kožo, bo injektor v teku približno 45 minut injiciral zdravilo Neulasta.
English: The elimination of pegfilgrastim is non-linear with respect to dose; serum clearance of pegfilgrastim decreases with increasing dose.
Slovenian: Izločanje pegfilgrastima iz telesa je glede na odmerek nelinearno; serumski očistek pegfilgrastima se z naraščajočim odmerkom zmanjšuje.
English: If someone else is injecting you, they can also use the back of your arms.
Slovenian: Če vam daje injekcijo kdo drug, vam jo lahko da tudi v zadnji del nadlakta.
English: The healthcare professional must ensure the patient receives appropriate training about the on-body injector and understands that if they suspect a device failure or malfunction the patient must immediately inform a healthcare professional as they may need a replacement dose.
Slovenian: Zdravstveni delavec mora poskrbeti, da je bolnik deležen ustreznega usposabljanja o injektorju ter da ve, da se mora v primeru suma na odpoved injektorja ali njegovo nepravilno delovanje nemudoma posvetovati z zdravstvenim delavcem, saj bo morda potreben nadomesten odmerek.
English: Push the plunger all the way down as far as it will go to inject all the liquid.
Slovenian: Potisnite bat povsem do konca, dokler gre, da boste injicirali vso tekočino.
English: In rat studies, it was shown that pegfilgrastim may cross the placenta.
Slovenian: V študijah na podganah so pokazali, da utegne pegfilgrastim prehajati posteljico.
English: • Belly, except for a 5 cm (2-inch) area right around your belly button.
Slovenian: • trebuh (razen v predelu 5 cm okrog popka).
English: The least-squares geometric mean ratios (90% CIs) (on-body injector to manual injection) were 0.97 (0.83, 1.14) for Cmax and 1.00 (0.84, 1.20) for AUC0-inf within the pre-specified bioequivalence limit of 0.80 to 1.25, and established bioequivalence between the two delivery methods of a single 6 mg dose of pegfilgrastim.
Slovenian: Geometrični sredini razmerij po metodi najmanjših kvadratov (90 % IZ) (injektor glede na ročno injiciranje) sta bili 0,97 (0,83; 1,14) za Cmax in 1,00 (0,84; 1,20) za AUC0-inf ter znotraj vnaprej določenih bioekvivalenčnih mej od 0,80 do 1,25; to potrjuje bioekvivalentnost obeh načinov uporabe enkratnega 6-mg odmerka pegfilgrastima.
English: In the event of a partial or missed dose, patients may be at increased risk of events such as neutropenia, febrile neutropenia and/or infection than if the dose had been correctly delivered.
Slovenian: V primeru delnega ali izpuščenega odmerka obstaja večje tveganje za učinke, kot so nevtropenija, febrilna nevtropenija in/ali okužbe, kakor bi bilo, če bi bil odmerek pravilno injiciran.
English: After injecting the liquid, remove the needle and let go of your skin.
Slovenian: Ko tekočino injicirate, izvlecite iglo in spustite kožo.
English: Special care should be taken when administering single or combination chemotherapeutic agents which are known to cause severe thrombocytopenia.
Slovenian: Posebna previdnost je potrebna med uporabo posameznih kemoterapevtikov ali njihovih kombinacij, za katere je znano, da povzročajo hudo trombocitopenijo.
English: Neulasta has no or negligible effect on the ability to drive or use machines.
Slovenian: Zdravilo Neulasta nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja s stroji.
English: After releasing the plunger, the pre-filled syringe safety guard will safely cover the injection needle.
Slovenian: Ko boste bat sprostili, bo varnostni ščitnik injekcijske brizge varno pokril injekcijsko iglo.
English: This may result in a missed or incomplete dose of Neulasta.
Slovenian: To lahko povzroči izpustitev odmerka ali nepopoln odmerek zdravila Neulasta.
English: • During this time, the on-body injector will flash a fast green light.
Slovenian: • Med tem časom bo lučka na injektorju hitro zeleno utripala.
English: Medication error as a result of device failure
Slovenian: Napaka pri uporabi zdravila kot posledica odpovedi pripomočka
English: Do not try to do this yourself, as you may accidently move it and dislodge the cannula from your skin leading to a missed or incomplete dose of Neulasta.
Slovenian: Ne poskušajte tega narediti sami, ker lahko injektor po nesreči premaknete, tako da gre kanila iz kože, posledica pa je izpuščen ali nepopoln odmerek zdravila Neulasta.
English: If you are injecting yourself and have forgotten your dose of Neulasta, you should contact your doctor to discuss when you should inject the next dose.
Slovenian: Če ste si pozabili injicirati zdravilo Neulasta Če si zdravilo injicirate sami in ste pozabili uporabiti odmerek zdravila Neulasta, se morate posvetovati z zdravnikom, da se bosta dogovorila, kdaj si morate injicirati naslednji odmerek.
English: EU/1/02/227/001 - 1 pack blistered syringe EU/1/02/227/002 - 1 pack unblistered syringe EU/1/02/227/004 - 1 pack blistered syringe with needle guard EU/1/02/227/005 - 1 pack blistered syringe with blistered on-body injector
Slovenian: EU/1/02/227/001 - pakiranje po 1 v pretisnem omotu EU/1/02/227/002 - pakiranje po 1 brez pretisnega omota EU/1/02/227/004 - pakiranje po 1 v pretisnem omotu s ščitnikom igle EU/1/02/227/005 - pakiranje po 1 v pretisnem omotu z injektorjem, ki se pritrdi na telo, v pretisnem omotu
English: The adhesive pad is water-resistant but you are advised to avoid submerging the on-body injector in water.
Slovenian: Lepljiva blazinica je vodoodporna, vendar svetujemo, da injektorja ne potapljate v vodo.
English: It may harm them,
Slovenian: Opazno vlažno (napojeno) lepilo
English: This medicine contains less than 1 mmol (23 mg) sodium per 6 mg dose, that is to say essentially ‘sodium-free'.
Slovenian: To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na 6 mg odmerek, kar v bistvu pomeni ˝brez natrija˝.
English: Human granulocyte colony stimulating factor (G-CSF) is a glycoprotein, which regulates the production and release of neutrophils from the bone marrow.
Slovenian: Faktor, ki stimulira človeške granulocitne kolonije (G-CSF), je glikoprotein, ki uravnava nastajanje nevtrofilcev in njihovo sproščanje iz kostnega mozga.
English: • if you have recently had a serious lung infection (pneumonia), fluid in the lungs (pulmonary oedema), inflammation of the lungs (interstitial lung disease) or an abnormal chest x-ray (lung infiltration).
Slovenian: • če ste nedavno imeli hudo okužbo pljuč (pljučnico), tekočino v pljučih (pljučni edem), vnetje pljuč (intersticijsko pljučno bolezen) ali nenormalen izvid rentgenskega slikanja pljuč (pljučne infiltrate).
English: Preclinical data from conventional studies of repeated dose toxicity revealed the expected pharmacological effects including increases in leukocyte count, myeloid hyperplasia in bone marrow, extramedullary haematopoiesis and splenic enlargement.
Slovenian: Predklinični podatki iz konvencionalnih študij toksičnosti pri ponavljajočih odmerkih so razkrili pričakovane farmakološke učinke, ki so zajemali zvišanje števila levkocitov, mieloidno hiperplazijo v kostnem mozgu, ekstramedularno hematopoezo in zvečanje vranice.
English: If the status light is flashing green, it is ok.
Slovenian: Če lučka zeleno utripa, je vse v redu.
English: Profile of median pegfilgrastim serum concentration and Absolute Neutrophil Count (ANC) in chemotherapy treated patients after a single 6 mg injection
Slovenian: Profil mediane serumske koncentracije pegfilgrastima in absolutnega števila nevtrofilcev (ANC - 'Absolute Neutrophil Count') pri bolnikih, zdravljenih s kemoterapijo, po eni sami 6 miligramski injekciji konc.
English: Three reported cases show a causal relationship between the adverse drug reaction (ADR) StevensJohnson syndrome and pegfilgrastim.
Slovenian: Trije poročani primeri kažejo na vzročno povezanost med neželenim učinkom zdravila (NUZ) Stevens-Johnsonov sindrom in pegfilgrastimom.
English: A Remove the pre-filled syringe tray from the package and gather the supplies needed for your injection: alcohol wipes, a cotton ball or gauze pad, a plaster and a sharps disposal container (not included).
Slovenian: A Vzemite podlogo z napolnjeno injekcijsko brizgo iz pakiranja in pripravite opremo, potrebno za injiciranje: alkoholne zložence, kosem vate ali zloženec gaze, obliž in vsebnik za ostre odpadke (ni priloženo).
English: Avoid getting lotions, creams, oils or cleaning agents near the on-body injector, as these products may loosen the adhesive.
Slovenian: Pazite, da v bližino injektorja ne pridejo losjoni, kreme, olja ali čistilna sredstva, ker lahko oslabijo lepilo.
English: • Tell your healthcare provider if you have had severe skin reactions to acrylic adhesives.
Slovenian: • Zdravniku morate povedati, če ste kdaj imeli hude kožne reakcije na akrilna lepila.
English: Step 3: Remove your on-body injector when dose delivery is complete A After the beep, check the colour of the status light.
Slovenian: 3. korak: Odstranite injektor, ko je injiciranje odmerka dokončano A Po pisku preverite barvo lučke stanja.
English: Do not administer pegfilgrastim to patients with a history of hypersensitivity to pegfilgrastim or filgrastim.
Slovenian: Pegfilgrastima ne dajajte bolnikom z anamnezo preobčutljivosti na pegfilgrastim ali filgrastim.
English: • during the monitoring of your on-body injector you are concerned that it is leaking; or
Slovenian: • če vas med nadziranjem injektorja skrbi, da ta pušča, ali
English: pegfilgrastim is not recommended during pregnancy and in women of childbearing potential not using contraception.
Slovenian: Pegfilgrastima ne uporabljajte pri nosečnicah in pri ženskah v rodni dobi, ki ne uporabljajo kontracepcije.
English: Consistent with a self-regulating clearance mechanism, the serum concentration of pegfilgrastim declines rapidly at the onset of neutrophil recovery (see figure 1).
Slovenian: V skladu z avtoregulacijskim mehanizmom očistka se serumska koncentracija pegfilgrastima ob nastopu okrevanja nevtrofilcev hitro zniža (glejte sliko 1).
English: • Do not sleep on the on-body injector or apply pressure during wear, especially during dose delivery.
Slovenian: • Ne spite na injektorju in medtem, ko ga nosite, nanj ne izvajajte pritiska, še zlasti ne med injiciranjem odmerka.
English: Nine hundred and twenty eight patients were randomised to receive either a single dose of pegfilgrastim or placebo approximately 24 hours (day 2) after chemotherapy in each cycle.
Slovenian: Devetstoosemindvajset bolnic so randomizirali na en odmerek pegfilgrastima ali placeba, uporabljen približno 24 ur (2. dan) po kemoterapiji v vsakem ciklusu.
English: The aim of this patient alert card is to help prevent medication errors including underdose resulting in lack of efficacy with the on-body injector device.
Slovenian: Namen te opozorilne kartice za bolnika je pomagati preprečiti napake pri uporabi zdravila s pripomočkom za injiciranje na telesu, vključno z nezadostnim odmerjanjem, ki povzroči izostanek učinka.
English: G-CSF can promote growth of myeloid cells, including malignant cells, in vitro and similar effects may be seen on some non-myeloid cells in vitro.
Slovenian: G-CSF lahko pospešuje rast mieloidnih celic, z malignimi celicami vred, in vitro, podobne učinke pa lahko vidimo na nekaterih nemieloidnih celicah in vitro.
English: These have generally occurred in patients with advanced malignant diseases, sepsis, taking multiple chemotherapy medications or undergoing apheresis (see section 4.4).
Slovenian: Ti primeri so se na splošno pojavili pri bolnikih z napredovalimi malignimi boleznimi, sepso, uporabo več zdravil za kemoterapijo ali zdravljenih z aferezo (glejte poglavje 4.4).
English: The symptoms experienced included fever, abdominal pain, malaise, back pain and increased inflammatory markers (e.g. c-reactive protein and white blood cell count).
Slovenian: Simptomi, ki so se pojavili, vključujejo povišano telesno temperaturo, bolečine v trebuhu, slabo počutje, bolečine v hrbtu in povišane vrednosti vnetnih označevalcev (npr. C-reaktivnega proteina in števila belih krvnih celic).
English: Due to the neutrophil-mediated clearance mechanism, the pharmacokinetics of pegfilgrastim is not expected to be affected by renal or hepatic impairment.
Slovenian: Zaradi mehanizma očistka, ki ga sprožijo nevtrofilci, ne pričakujemo, da bi na farmakokinetiko pegfilgrastima vplivala ledvična ali jetrna okvara.
English: Ask your doctor or pharmacist for advice before taking any medicine.
Slovenian: Posvetujte se z zdravnikom ali farmacevtom, preden vzamete katero koli zdravilo.
English: How to use Neulasta
Slovenian: Kako uporabljati zdravilo Neulasta
English: B Examine the injection site.
Slovenian: B Preglejte mesto injiciranja.
English: The MAH shall ensure that in each Member State where Neulasta on-body injector is marketed, all patients/carers who are expected to use Neulasta on-body injector are provided with a patient alert card to be disseminated through the prescribing physicians.
Slovenian: Imetnik dovoljenja za promet z zdravilom mora v vseh državah članicah, kjer bo tržil zdravilo Neulasta z injektorjem, ki se pritrdi na telo, zagotoviti, da bodo zdravniki, ki bodo predpisovali zdravilo, vsem bolnikom/skrbnikom, za katere se pričakuje, da bodo uporabljali zdravilo Neulasta z injektorjem, dali opozorilno kartico za bolnika.
English: After a single subcutaneous dose of pegfilgrastim, the peak serum concentration of pegfilgrastim occurs at 16 to 120 hours after dosing and serum concentrations of pegfilgrastim are maintained during the period of neutropenia after myelosuppressive chemotherapy.
Slovenian: Po enem samem subkutanem odmerku pegfilgrastima se najvišja serumska koncentracija pegfilgrastima pojavi 16 do 120 ur po odmerku, serumske koncentracije pegfilgrastima se vzdržujejo v obdobju nevtropenije po mielosupresivni kemoterapiji.
English: What Neulasta is and what it is used for What you need to know before you use Neulasta How to use Neulasta
Slovenian: Kaj je zdravilo Neulasta in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Neulasta Kako uporabljati zdravilo Neulasta Možni neželeni učinki
English: For subcutaneous use.
Slovenian: za subkutano uporabo
English: Common cases of leukocytosis (White Blood Count [WBC] > 100 x 10
Slovenian: Pogosto so poročali o primerih levkocitoze (število belih krvničk > 100 x 10
English: *Sodium acetate is formed by titrating glacial acetic acid with sodium hydroxide.
Slovenian: *Natrijev acetat nastane s titracijo ledocetne kisline z natrijevim hidroksidom.
English: Treatment with pegfilgrastim alone does not preclude thrombocytopenia and anaemia because full dose myelosuppressive chemotherapy is maintained on the prescribed schedule.
Slovenian: Zdravljenje s samim pegfilgrastimom ne prepreči trombocitopenije in anemije, ker se hkrati vzdržuje mielosupresivna kemoterapija s polnimi odmerki po predpisani shemi.
English: Remember
Slovenian: Ne pozabite
English: Glomerulonephritis
Slovenian: Glomerulonefritis
English: • bleeding from the lung (pulmonary haemorrhage).
Slovenian: • krvavitev iz pljuč (pljučna hemoragija).
English: Red flashing status light
Slovenian: Rdeča utripajoča lučka stanja
English: • Sweet's syndrome (plum-coloured, raised, painful lesions on the limbs and sometimes the face and neck with fever) has occurred but other factors may play a role.
Slovenian: • Sweetov sindrom (izbočene, boleče spremembe slivove barve na okončinah in včasih tudi na obrazu in vratu s povišano telesno temperaturo), vendar tu lahko vplivajo tudi drugi dejavniki.
English: For the next 45 minutes, monitor your on-body injector frequently for leaks during dose delivery.
Slovenian: V naslednjih 45 minutah pogosto nadzorujte injektor glede puščanja med injiciranjem odmerka.
English: • spleen rupture.
Slovenian: • ruptura vranice.
English: On-body injector, the fluid path is made from polypropylene, cyclic olefin copolymer, silicone rubber and fluorinated ethylene propylene (FEP), with a stainless steel 28 gauge needle.
Slovenian: Tekočinska pot injektorja je izdelana iz polipropilena, cikličnega olefinskega kopolimera, silikonske gume in fluoriranega etilenpropilena (FEP) z iglo številka 28 iz nerjavnega jekla.
English: How do I give my injection?
Slovenian: Kako naj si dam injekcijo?
English: Excipients with known effect Each pre-filled syringe contains 30 mg sorbitol (E420) (see section 4.4).
Slovenian: Pomožne snovi z znanim učinkom: Ena napolnjena injekcijska brizga vsebuje 30 mg sorbitola (E420) (glejte poglavje 4.4).
English: • pain at the site of injection.
Slovenian: • bolečina na mestu injiciranja.
English: You can now use the pre-filled syringe.
Slovenian: Zdaj lahko napolnjeno injekcijsko brizgo uporabite.
English: C Inspect the medicine and pre-filled syringe.
Slovenian: C Preglejte zdravilo in napolnjeno injekcijsko brizgo.
English: Uncommonly, cases have resulted in respiratory failure or ARDS, which may be fatal (see section 4.4).
Slovenian: Občasno so ti primeri povzročili respiratorno insuficienco ali ARDS, ki sta lahko smrtno nevarna (glejte poglavje 4.4).
English: Neulasta is used to reduce the duration of neutropenia (low white blood cell count) and the occurrence of febrile neutropenia (low white blood cell count with a fever) which can be caused by the use of cytotoxic chemotherapy (medicines that destroy rapidly growing cells).
Slovenian: Zdravilo Neulasta se uporablja za skrajšanje trajanja nevtropenije (zmanjšano število belih krvničk) in zmanjševanje pojavljanja febrilne nevtropenije (zmanjšano število belih krvničk z zvišano telesno temperaturo), ki ju lahko povzroča uporaba citotoksične kemoterapije (zdravila, ki uničujejo hitro rastoče celice).
English: Urinalysis monitoring is recommended.
Slovenian: Priporočljivo je spremljanje laboratorijskih izvidov urina.
English: The usual dose is one 6 mg subcutaneous injection (injection under your skin) and it should be given at least 24 hours after your last dose of chemotherapy at the end of each chemotherapy cycle.
Slovenian: Običajni odmerek je ena 6 miligramska subkutana injekcija (podkožna injekcija), ki jo morate prejeti vsaj 24 ur po zadnjem odmerku kemoterapije na koncu vsakega cikla kemoterapije.
English: The on-body injector will flash a fast green light.
Slovenian: Lučka injektorja bo hitro zeleno utripala.
English: • increased spleen size.
Slovenian: • povečana vranica.
English: A diagnosis of splenic rupture should be considered in patients reporting left upper abdominal pain or shoulder tip pain.
Slovenian: Na diagnozo rupture vranice moramo misliti pri bolnikih, ki poročajo o bolečini v zgornjem levem delu trebuha ali v predelu lopatice.
English: After use
Slovenian: Po uporabi