FrancophonIA/ELRC3.0 huggingface dataset:
English: • The dose is the same for all persons aged 6 years and older.
Slovenian: • Odmerek je za vse osebe, stare 6 let ali več, enak.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/18/1350/001
Slovenian: ŠTEVILKA(E) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/18/1350/001
English: In addition, the corresponding frequency category is provided using the following convention: Very common (≥ 1/10); Common (≥ 1/100 to < 1/10); Uncommon (≥ 1/1,000 to < 1/100); Rare (≥ 1/10,000 to < 1/1,000); Very rare
Slovenian: Poleg tega je navedena tudi ustrezna kategorija pogostnosti v skladu z naslednjim dogovorom: zelo pogosti (≥1/10); pogosti (≥1/100 do <1/10); občasni (≥1/1.000 do <1/100); redki (≥1/10.000 do <1/1.000); zelo redki
English: Repeat cycle
Slovenian: Ponovite cikel
English: 82319 Starnberg Germany
Slovenian: D-82319 Starnberg
English: Some side effects can be serious
Slovenian: Nekateri neželeni učinki so lahko resni
English: Each additional 6 months of treatment resulted in incremental increases similar in magnitude to that observed in the 6 months of controlled studies.
Slovenian: Vsako dodatno 6-mesečno zdravljenje je povzročilo inkrementalno povečanje, po velikosti podobno tistemu v 6-mesečnih kontroliranih študijah.
English: • Loss of voice
Slovenian: • izguba glasu
English: Tell your doctor or a pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Slovenian: Obvestite zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katero koli drugo zdravilo, tudi če ste ga dobili brez recepta.
English: These medicines may cause muscle weakness to appear or become worse.
Slovenian: Ta zdravila lahko povzročajo mišično šibkost ali njeno poslabšanje.
English: Children The medicine is not intended for use in children under 6 years of age.
Slovenian: Otroci To zdravilo ni namenjeno za uporabo pri otrocih, starih manj kot 6 let.
English: • Keep the rest of the medicine refrigerated in the original box.
Slovenian: • Preostalo zdravilo shranjujte v hladilniku v originalni škatli.
English: Less than 10% of tobramycin is bound to plasma proteins.
Slovenian: Manj kot 10 % tobramicina se veže na beljakovine plazme.
English: If the infection is not properly treated, it continues to damage the lungs, causing further problems with breathing.
Slovenian: Če se okužba ne zdravi ustrezno, še naprej škoduje pljučem in tako povzroča nadaljnje težave z dihanjem.
English: • voice alteration (hoarseness)
Slovenian: • sprememba glasu (hripavost)
English: Opened ampoule should never be stored for re-use.
Slovenian: Odprtih ampul se ne sme shranjevati za ponovno uporabo.
English: • hyperventilating, low oxygen levels in your blood, sinusitis
Slovenian: • hiperventilacija, nizke ravni kisika v krvi, sinusitis
English: The recommended dose is two ampoules each day (one in the morning and one in the evening) for 28 days.
Slovenian: Priporočeni odmerek sta dve ampuli vsak dan (ena zjutraj in ena zvečer) v 28-dnevnem obdobju.
English: Hold the nebuliser handset horizontally and breath normally through your mouth.
Slovenian: Nebulator držite vodoravno in normalno dihajte skozi usta.
English: This damages the bacteria and eventually kills them.
Slovenian: To bakterijo poškoduje in ščasoma ubije.
English: Sputum concentrations were higher and more variable with Cmax of 1,951 + 2,187 µg/g.
Slovenian: Koncentracije v izpljunku so bile višje in bolj variabilne s Cmax 1.951 + 2.187 µg/g.
English: Never store an opened ampoule.
Slovenian: Odprte ampule nikoli ne shranite.
English: Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Slovenian: Pri zdravljenju je treba upoštevati uradne smernice o ustrezni uporabi antibakterijskih zdravil.
English: The elimination half-life of tobramycin from serum is approximately 2 hours.
Slovenian: Razpolovni čas izločanja tobramicina iz seruma je približno 2 uri.
English: • If you need to interrupt your treatment for any reason, press and hold the On/Off button for one full second.
Slovenian: • Če morate zdravljenje zaradi katerega koli razloga prekiniti, pritisnite in držite gumb za vklop/izklop eno celo sekundo.
English: PHARMACEUTICAL FORM AND CONTENTS Contains 8 ampoules.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Vsebuje 8 ampul.
English: PARI Pharma GmbH Lochhamer Schlag 21 82166 Graefelfing GERMANY
Slovenian: PARI Pharma GmbH Lochhamer Schlag 21 82166 Graefelfing
English: The dose interval should be as close as possible to 12 hours and not less than 6 hours.
Slovenian: Interval odmerjanja mora biti čim bližje 12 uram in ne manj kot 6 ur.
English: Do not use this medicine if you notice that it has become cloudy, or if there are particles in the solution.
Slovenian: Ne uporabljajte tega zdravila, če opazite, da je raztopina motna ali da so v njej delci.
English: If the product has been stored at room temperature for longer than 4 weeks, it has to be disposed according to local requirements.
Slovenian: Zdravilo, ki ste ga pri sobni temperaturi shranjevali dlje kot 4 tedne, zavrzite v skladu z lokalnimi zahtevami.
English: When all of the medicine has been delivered, you will hear the “treatment complete” tone.
Slovenian: Ko je zdravilo porabljeno, boste slišali zvok, ki pomeni »konec zdravljenja«.
English: If you don't have a refrigerator available (such as when you are transporting your medicine) you can store the box with the medicine (sachets opened or unopened) below 25°C for up to 4 weeks.
Slovenian: Če hladilnik ni na voljo (na primer med transportom zdravila), lahko škatlo z zdravilom (odprte ali neodprte vrečice) do 4 tedne shranjujete pri temperaturi do 25 °C.
English: Make sure the nebuliser handset is on a flat, stable surface.
Slovenian: Nebulator postavite na ravno, stabilno površino.
English: • ringing in the ears (normally transient), hearing loss, dizziness
Slovenian: • zvonjenje v ušesih (običajno prehodno), izguba sluha, omotica
English: Geometric Standard Deviation ±SD 1.5 ± 0.0 Nebulisation Time [min]
Slovenian: Geometrična standardna deviacija ± SD 1,5 ± 0,0 Čas nebulizacije [min]
English: It is not known whether inhaling this medicine while you are pregnant causes side effects.
Slovenian: Ni znano, ali inhaliranje tega zdravila med nosečnostjo povzroča neželene učinke.
English: Any unused medicinal product or waste material should be disposed off in accordance with local requirements.
Slovenian: Neuporabljeno zdravilo ali odpadni material zavrzite v skladu z lokalnimi predpisi.
English: These may still occur while using Vantobra, but should not be as frequent or worse than before.
Slovenian: Ti se lahko med uporabo zdravila Vantobra še vedno pojavljajo, vendar ne smejo biti tako pogosti in v tako hudi obliki kot prej.
English: Do not use an alternative untested nebuliser system because it may alter the amount of medicine reaching the lungs.
Slovenian: Ne uporabljajte alternativnih, netestiranih nebulatorskih sistemov, saj lahko spremenijo količino zdravila, ki doseže pljuča.
English: It works by disrupting the production of proteins that the bacteria need to build their cell walls.
Slovenian: Deluje tako, da ovira nastajanje proteinov, ki jih bakterija potrebuje za izgradnjo svojih celičnih sten.
English: Bronchospasm should be treated as medically appropriate.
Slovenian: Bronhospazem je treba ustrezno zdraviti.
English: • furosemide, a diuretic (“water tablet”);
Slovenian: • furosemida, ki je diuretik (»tableta za odvajanje vode«)
English: Stability after opening of the sachet: 4 weeks when stored below 25 °C
Slovenian: Stabilnosti po odprtju vrečice: 4 tedne pri temperaturi do 25 °C.
English: You then start another course after the break (as illustrated).
Slovenian: Nato po premoru začnite z naslednjim ciklom (kot je prikazano).
English: It acts primarily by disrupting protein synthesis leading to altered cell membrane permeability, progressive disruption of the cell envelope and eventual cell death.
Slovenian: Deluje predvsem tako, da ovira sintezo proteinov, kar spremeni prepustnost celične membrane in povzroči progresiven razkroj celične ovojnice in posledično smrt celice.
English: See also information on clinical benefit and tolerability in sections 4.4, 4.8 and
Slovenian: Glejte tudi podatke o kliničnih koristih in prenosljivosti v poglavjih 4.4, 4.8 in 5.1.
English: • blood in your sputum (the substance you cough up);
Slovenian: • kri v izpljunku (v vsebini, ki jo izkašljate)
English: Insusceptible Burkholderia cepacia Stenotrophomonas maltophilia Alcaligenes xylosoxidans
Slovenian: Burkholderia cepacia Stenotrophomonas maltophilia Alcaligenes xylosoxidans
English: A package is sufficient for one treatment cycle of 28 days.
Slovenian: Pakiranje zadošča za en 28-dnevni cikel zdravljenja.
English: • worsening of lung function test results
Slovenian: • poslabšanje rezultatov testiranja pljučne funkcije
English: Do not use the Tolero nebuliser handset for any other medicine.
Slovenian: Nebulatorja Tolero ne uporabljajte za druga zdravila.
English: No evidence of drug interactions with these medicines was identified.
Slovenian: Znakov medsebojnega delovanja z navedenimi zdravili niso ugotovili.
English: • headache, weakness
Slovenian: • glavobol, šibkost
English: Vantobra is taken in alternating cycles of 28 days.
Slovenian: Zdravilo Vantobra se uporablja v izmeničnih 28-dnevnih ciklih.
English: Ampoules are packed in sachets, one sachet contains 8 ampoules which correspond with 4 days of treatment.
Slovenian: Ampule so pakirane v vrečice, ena vrečica vsebuje 8 ampul, kar ustreza štirim dnevom zdravljenja.
English: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products in the nebuliser.
Slovenian: Zaradi pomanjkanja študij kompatibilnosti zdravila ne smemo mešati z drugimi zdravili v nebulatorju.
English: • if you are allergic (hypersensitive) to tobramycin, to any type of aminoglycoside antibiotics, or to any of the other ingredients of Vantobra (listed in section 6).
Slovenian: • če ste alergični (preobčutljivi) na tobramicin, katero koli vrsto aminoglikozidnih antibiotikov ali katero koli sestavino zdravila Vantobra (navedeno v poglavju 6).
English: If you have problems with your hearing or kidney function, your doctor may take blood samples to monitor the amount of Vantobra in your system.
Slovenian: Če imate težave s sluhom ali delovanjem ledvic, bo morda zdravnik vzel krvni vzorec, s katerim bo spremljal količino zdravila Vantobra v vašem sistemu.
English: If you forget to use Vantobra and there are at least 6 hours to your next dose, use your dose as soon as you can.
Slovenian: Če ste pozabili uporabiti zdravilo Vantobra in je do naslednjega odmerka več kot 6 ur, uporabite odmerek takoj, ko ga lahko.
English: The performance parameters from in vitro aerosol characterisation studies are identical for the two controllers and are shown in section 5.1, Table 2.
Slovenian: Parametri učinka iz študij značilnosti aerosola in vitro so identični za oba krmilnika in prikazani v poglavju 5.1, preglednica 2.
English: • Hold the ampoule upright and tap lightly before twisting off the head part to avoid spilling.
Slovenian: • Ampulo držite pokonci in po njej rahlo potapkajte, preden jiodstranite naglavni del; pazite, da ne polijete.
English: There is no evidence that patients treated with up to 18 months with tobramycin nebuliser solution were at a greater risk for acquiring B. cepacia, S. maltophilia or A. xylosoxidans, than would be expected in untreated patients.
Slovenian: Ni znakov, da bi bili bolniki, zdravljeni z raztopino tobramicina za nebulator do 18 mesecev, bolj izpostavljeni tveganju za okužbo z B. cepacia, S. maltophilia ali A. xylosoxidans, kot se pričakuje pri nezdravljenih bolnikih.
English: Inhalation should be performed by applying a normal breathing pattern without interruption.
Slovenian: Zdravilo se mora inhalirati v običajnem vzorcu dihanja brez prekinitev.
English: The contents of a single-dose ampoule should be used immediately after opening (see section 6.6).
Slovenian: Vsebino ampule z enim odmerkom uporabite takoj po odprtju (glejte poglavje 6.6).
English: PHARMACEUTICAL FORM AND CONTENTS Package contains
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Pakiranje vsebuje
English: Do not stop using Vantobra unless your doctor tells you to do so, as your lung infection may not be controlled sufficiently and may become worse.
Slovenian: Ne prenehajte uporabljati zdravila Vantobra, razen če vam tako naroči zdravnik, saj v tem primeru vaša pljučna okužba ne bo ustrezno obvladovana in se lahko poslabša.
English: As a result of study 12012.101, lung function improvement FEV1% predicted relative to baseline increased by 8.2 ± 9.4% under Vantobra and by 4.8 ± 9.6% under the reference therapy in the first treatment cycle showing non-inferior (p=0.0005) efficacy.
Slovenian: Kot rezultat študije 12012.101 se je izboljšanje pljučne funkcije FEV1 % glede na vrednost na začetku zdravljenja povečalo za 8,2 ± 9,4 % pri zdravilu Vantobra in za 4,8 ± 9,6 % pri referenčnem zdravljenju v prvem ciklju zdravljenja, kar kaže na neinferiornost (p = 0,0005) učinkovitosti.
English: For detailed instructions on use see section 6.6.
Slovenian: Za podrobna navodila glede uporabe glejte poglavje 6.6.
English: Please check this order with your doctor as well.
Slovenian: O tem vrstnem redu se posvetujte tudi z zdravnikom.
English: Aspergillus species were more frequently recovered from the sputum of treated patients; however, clinical sequelae such as Allergic Bronchopulmonary Aspergillosis (ABPA) were reported rarely and with similar frequency as in the control group.
Slovenian: Iz izpljunka zdravljenih bolnikov so pogosteje izolirali vrste Aspergillus, vendar pa so o kliničnih posledicah, kot so alergijska bronhopulmonarna aspergiloza (ABPA-Allergic Bronchopulmonary Aspergillosis) poročali redko in s podobno pogostnostjo kot v kontrolni skupini.
English: Limited data from one controlled clinical study over one treatment cycle indicate that the improvement in lung function was maintained above baseline during the 28-day off-treatment period.
Slovenian: Omejeni podatki, ki so na voljo iz ene kontrolirane klinične študije za en cikel zdravljenja, kažejo, da se je izboljšanje pljučne funkcije ohranilo nad vrednostjo na začetku zdravljenja v 28-dnevnem obdobju brez zdravljenja.
English: People with cystic fibrosis have many symptoms of the disease.
Slovenian: Bolniki s cistično fibrozo imajo lahko več simptomov bolezni.
English: The dose of Vantobra is the same for all patients within the approved age range, regardless of age or weight.
Slovenian: Odmerjanje Odmerek zdravila Vantobra je v odobrenem starostnem okviru enak za vse bolnike, ne glede na starost ali telesno maso.
English: If you inhale too much Vantobra you may get a very hoarse voice.
Slovenian: Če inhalirate preveč zdravila Vantobra, lahko postane vaš glas zelo hripav.
English: Animal studies do not indicate a teratogenic effect of tobramycin (see section 5.3).
Slovenian: Študije na živalih ne kažejo teratogenih učinkov tobramicina (glejte poglavje 5.3).
English: • It is best to have an interval as close as possible to 12 hours between doses, but this interval must be at least 6 hours.
Slovenian: • Najbolje je, da je interval, ki mine med dvema odmerkoma, čim bližje 12 uram, vendar pa mora biti interval vsaj 6 ur.
English: Outer box contains:
Slovenian: Zunanja škatla vsebuje:
English: Vantobra should not be used during pregnancy unless the benefits to the mother outweigh the risks to the foetus or baby.
Slovenian: Zdravilo Vantobra se med nosečnostjo ne sme uporabljati, razen če so koristi za mater večje od možnega tveganja za plod ali dojenčka.
English: • laryngitis (inflammation of the voice box that can cause voice alteration, sore throat and difficulty swallowing)
Slovenian: • laringitis (vnetje glasilk, ki lahko povzroči spremembo glasu, vneto žrelo in težave pri požiranju)
English: Your doctor may ask you to use other appropriate medicines to widen the airways before using Vantobra.
Slovenian: Vaš zdravnik vas bo morda prosil, da uporabljate ustrezna zdravila za razširitev dihalnih poti, preden uporabite zdravilo Vantobra.
English: • muscle weakness that lasts or becomes worse over time, a symptom mostly related to conditions such as myasthenia (muscle weakness) or Parkinson's disease.
Slovenian: • šibkost mišic, ki vztraja ali se sčasoma še slabša, kar je večinoma simptom pri boleznih, kot sta miastenija (šibkost mišic) ali Parkinsonova bolezen
English: Teratogenicity could not be assessed at higher parenteral doses in rabbits as they induced maternal toxicity and abortion.
Slovenian: Teratogenosti pri višjih parenteralnih odmerkih pri samicah kuncev niso mogli oceniti, saj je zdravilo povzročilo maternalno toksičnost in splav.
English: The development of antibiotic-resistant P. aeruginosa and superinfection with other pathogens represent potential risks associated with antibiotic therapy.
Slovenian: Razvoj na antibiotike odpornega povzročitelja P. aeruginosa in superinfekcij z drugimi patogeni predstavlja možno tveganje, povezano z zdravljenjem z antibiotiki.
English: OFF Vantobra Use Vantobra twice a day for 28 days Do not use any Vantobra for the next 28 days
Slovenian: Brez uporabe zdravila Vantobra Zdravilo Vantobra uporabljajte 28 dni dvakrat na dan Naslednjih 28 dni zdravila Vantobra ne uporabljajte
English: Concurrent use of Vantobra with diuretic compounds (such as ethacrynic acid, furosemide, urea or mannitol) is not recommended.
Slovenian: Sočasna uporaba zdravila Vantobra z diuretiki (kot so etakrinska kislina, furosemid, urea ali manitol) ni priporočena.
English: This does not change how Vantobra works provided that the storage instructions have been followed.
Slovenian: To ne vpliva na način delovanja zdravila Vantobra, če je bilo shranjeno po navodilih za shranjevanje.
English: Based on available data from animals a risk of toxicity (e.g. ototoxicity) at prenatal exposure levels cannot be excluded.
Slovenian: Na podlagi razpoložljivih podatkov iz študij na živalih tveganja za toksično delovanje (npr. ototoksičnost) pri stopnjah izpostavljenosti pred rojstvom ni mogoče izključiti.
English: The respective controller can be prescribed by your physician or purchased separately.
Slovenian: Zadevni krmilnik vam je predpisal zdravnik ali ste ga kupili posebej.
English: Serum concentrations greater than 12 µg/ml are associated with tobramycin toxicity and treatment should be discontinued if concentrations exceed this level.
Slovenian: Serumske koncentracije, ki presegajo 12 μg/ml, so povezane s toksičnim delovanjem tobramicina, zato je treba zdravljenje prekiniti, če koncentracije presegajo to vrednost.
English: However, aminoglycosides can cause foetal harm (e.g., congenital deafness and nephrotoxicity) when high systemic concentrations are achieved in a pregnant woman.
Slovenian: Vendar lahko aminoglikozidi škodujejo plodu (povzročijo lahko npr. prirojeno gluhost in nefrotoksičnost), kadar pri nosečnici dosegajo visoke sistemske koncentracije.
English: In the case of any overdose, the possibility of drug interactions with alterations in the elimination of Vantobra or other medicinal products should be considered.
Slovenian: V primeru kateregakoli prevelikega odmerjanja je treba upoštevati možnost medsebojnega delovanja zdravil s spremembami v izločanju zdravila Vantobra ali drugih zdravil.
English: If you are taking several different treatments for cystic fibrosis, you should take them in the following order:
Slovenian: Če zaradi cistične fibroze uporabljate več različnih načinov zdravljenja, naj bo vrstni red naslednji:
English: Long-term safety data are not available for Vantobra (see also section 5.1).
Slovenian: Podatki o varnosti dolgotrajne uporabe zdravila Vantobra niso na voljo (glejte tudi poglavje 5.1).
English: Systemic exposure following inhalation of Vantobra is very low (see section 5.2).
Slovenian: Sistemska izpostavljenost zdravilu Vantobra po inhalaciji je zelo majhna (glejte poglavje 5.2).
English: • Use Vantobra only with the Tolero nebuliser handset shown in the picture below to make sure you inhale the correct dose.
Slovenian: • Zdravilo Vantobra uporabljajte le z nebulatorjem Tolero, ki je prikazan na spodnji sliki, in se prepričajte, da inhalirate pravilni odmerek.
English: This means that Vantobra may not work as well as it should over time.
Slovenian: To pomeni, da lahko zdravilo Vantobra sčasoma začne delovati slabše, kot bi moralo.
English: In repeated dose toxicity studies it has been shown that target organs of toxicity are the kidneys and vestibular/cochlear functions.
Slovenian: V študijah toksičnosti s ponavljajočimi odmerki se je pokazalo, da so glavni ciljni organi toksičnosti ledvice in vestibularne/kohlearne funkcije.
English: If you have questions about how long to use Vantobra, talk to your doctor or pharmacist.
Slovenian: Če imate vprašanja glede tega, kako dolgo jemati zdravilo Vantobra, se obrnite na zdravnika ali farmacevta.
English: Do not use a double dose to make up for a forgotten dose.
Slovenian: Ne uporabite dvojnega odmerka, če ste pozabili uporabiti prejšnji odmerek.
English: Within each system organ class, the adverse drug reactions are ranked by frequency, with the most frequent reactions first.
Slovenian: V okviru vsakega organskega sistema so neželeni učinki razvrščeni po pogostnosti, pri čemer so najprej navedeni najbolj pogosti neželeni učinki.
English: Tel.: +49 (0) 89 - 74 28 46 - 10 Fax:
Slovenian: Faks: +49 (0) 89 - 74 28 46 - 30 E-pošta: info@paripharma.com
English: Pseudomonas aeruginosa Haemophilus influenzae Staphylococcus aureus
Slovenian: Pseudomonas aeruginosa Haemophilus influenzae Staphylococcus aureus neobčutljivi
English: CFU reduction as an indicator for suppression of P. aeruginosa was comparable for Vantobra and the reference product.
Slovenian: Zmanjšanje CFU kot pokazatelj supresije P. aeruginosa je bilo primerljivo za zdravilo Vantobra in za referenčno zdravilo.
English: Other information
Slovenian: Druge informacije
English: Preparing Vantobra for inhalation
Slovenian: Priprava zdravila Vantobra za inhalacijo
English: Aerosol characteristics
Slovenian: Značilnosti aerosola
English: • other medicines with diuretic potential such as urea or mannitol;
Slovenian: • drugih zdravil, ki delujejo diuretično, kot sta urea ali manitol
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.
Slovenian: Nosečnost in dojenje Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom,
English: • It is important that you keep using the medicine twice each day during your 28 days on treatment, and that you keep to the 28-day on / 28-day off cycle.
Slovenian: • Pomembno je, da med 28-dnevnim zdravljenjem zdravilo uporabite vsak dan dvakrat in da upoštevate 28-dnevni cikel zdravljenja in 28-dnevni cikel brez njega.
English: The recommended dose is one ampoule (170 mg/1.7 ml) administered twice daily (i.e. total daily dose is 2 ampoules) for 28 days.
Slovenian: Priporočeni odmerek je ena ampula (170 mg/1,7 ml) dvakrat na dan (tj. skupni dnevni odmerek sta 2 ampuli) 28 dni zapored.
English: The serum concentration of tobramycin should only be monitored using validated methods.
Slovenian: Serumsko koncentracijo tobramicina je treba meriti samo z validiranimi metodami.
English: • chest pain or general pain
Slovenian: • bolečine v prsnem košu ali splošne bolečine
English: Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system listed in Appendix V. 4.9 Overdose
Slovenian: Od zdravstvenih delavcev se zahteva, da poročajo o katerem koli domnevnem neželenem učinku zdravila na nacionalni center za poročanje, ki je naveden v Prilogi V.
English: • anticholinesterases such as neostigmine and pyridostigmine (used to treat muscle weakness), or botulinum toxin.
Slovenian: • antiholinesteraze, kot sta neostigmin in piridostigmin (za zdravljenje mišične šibkosti), ali botulinski toksin.
English: Assessment of tobramycin serum concentrations may be helpful in monitoring overdose.
Slovenian: Ocena koncentracij serumskega tobramicina je lahko koristna pri spremljanju prevelikega odmerjanja.