FrancophonIA/ELRC3.0 huggingface dataset:
English: Malformations have been observed in foetuses from efavirenz-treated monkeys (see section 5.3).
Danish: Der er blevet observeret misdannelser hos fostre hos efavirenz-behandlede aber (se pkt.
English: Exacerbations of hepatitis after discontinuation of treatment: In HIV infected patients co-infected with HBV, clinical and laboratory evidence of hepatitis may occur after discontinuation of treatment (see section 4.4).
Danish: Forværring af hepatitis efter seponering af behandling: Hos hiv-inficerede patienter, som samtidig er inficeret med HBV, kan der fremkomme klinisk og laboratoriemæssig evidens for hepatitis efter seponering af behandlingen (se pkt.
English: • fatty liver
Danish: • Fedtlever
English: (CYP3A4 and CYP2B6 induction)
Danish: (CYP3A4- og CYP2B6-induktion)
English: There is insufficient information on the effects of efavirenz, emtricitabine and tenofovir in newborns/infants.
Danish: Der foreligger utilstrækkelige data for virkningen af efavirenz, emtricitabin og tenofovir på det ammede barn.
English: As a fixed combination, Atripla should not be administered concomitantly with other medicinal products containing the same active components, emtricitabine or tenofovir disoproxil.
Danish: Som en fast kombination bør Atripla ikke gives samtidigt med andre lægemidler, der indeholder de samme aktive komponenter, emtricitabin eller tenofovirdisoproxil.
English: No dose adjustment is necessary for efavirenz.
Danish: Justering af efavirenzdosis er ikke nødvendig.
English: Elderly patients are more likely to have decreased hepatic or renal function, therefore caution should be exercised when treating elderly patients with Atripla (see section 4.2).
Danish: Da det er mere sandsynligt, at ældre patienter har nedsat lever- eller nyrefunktion, skal der udvises forsigtighed ved behandling af ældre patienter med Atripla (se pkt.
English: Some examples include: - aminoglycosides, vancomycin (medicines for bacterial infections) - foscarnet, ganciclovir, cidofovir (medicines for viral infections) - amphotericin B, pentamidine (medicines for fungal infections) - interleukin-2 (to treat cancer) - non-steroidal anti-inflammatory drugs (NSAIDs, to relieve bone or muscle pains)
Danish: Fortæl det til lægen hvis De tager anden medicin, som kan skade Deres nyrer, f.eks.: - Aminoglykosider, vancomycin (mod bakterieinfektioner) - Foscarnet, ganciclovir, cidofovir (mod virusinfektioner) - Amphotericin B, pentamidin (mod svampeinfektioner) - Interleukin-2 (til behandling af kræft) - Non-steroide antiinflammatoriske midler (NSAID'er, til at lindre knogle- eller muskelsmerter)
English: Common diarrhoea, vomiting, abdominal pain, nausea elevated amylase including elevated pancreatic amylase, elevated serum lipase, vomiting, abdominal pain, dyspepsia abdominal pain, abdominal distension, flatulence
Danish: Forhøjet amylase herunder forhøjet pancreas-amylase, forhøjet serum-lipase, opkastning, abdominalsmerter, dyspepsi
English: Depomedroxyprogesterone acetate (DMPA)/Efavirenz (150 mg IM single dose DMPA)
Danish: Depomedroxyprogesteronacetat (DMPA)/efavirenz (150 mg i.m.
English: Voriconazole:
Danish: Voriconazol:
English: Integrase strand transfer inhibitor Raltegravir/Efavirenz (400 mg single dose/-)
Danish: Integrase strand transfer-hæmmer Raltegravir/efavirenz (400 mg enkeltdosis/-)
English: Rare completed suicide3,4, delusion3,4, neurosis3,4 Nervous system disorders: Very common headache dizziness
Danish: Fuldbyrdet selvmord3,4, vrangforestillinger3,4, neuroser3,4
English: The safety and efficacy of Atripla in children under the age of 18 years have not been established.
Danish: Atriplas sikkerhed og virkning hos børn og unge under 18 år er ikke klarlagt.
English: Patients must not have experienced virological failure on any prior antiretroviral therapy and must be known not to have harboured virus strains with mutations conferring significant resistance to any of the three components contained in Atripla prior to initiation of their first antiretroviral treatment regimen (see sections 4.4 and 5.1).
Danish: Patienter må ikke tidligere have oplevet virologisk svigt under antiretroviral behandling, og de må ikke før deres første antiretrovirale behandling have haft virustammer med mutationer, der kan give signifikant resistens over for en eller flere af de tre komponenter, som Atripla indeholder (se pkt.
English: Bone abnormalities (infrequently contributing to fractures) may be associated with proximal renal tubulopathy (see section 4.8).
Danish: Knogleabnormiteter (i sjældne tilfælde medvirkende årsag til frakturer) kan forekomme i forbindelse med proximal renal tubulopati (se pkt.
English: Buprenorphine:
Danish: Buprenorphin:
English: Since Atripla is a fixed-dose combination product, the dose of efavirenz cannot be altered (see section 4.5).
Danish: Da Atripla er et fastdosis kombinationsprodukt, kan efavirenzdosis ikke ændres (se pkt.
English: Atripla should not be co-administered with products containing efavirenz unless needed for dose adjustment e.g. with rifampicin (see section 4.2).
Danish: Atripla bør ikke administreres samtidigt med lægemidler, der indeholder efavirenz, medmindre det er nødvendigt på grund af dosisjustering, f.eks. med rifampicin (se pkt.
English: Lumefantrine:
Danish: Lumefantrin:
English: Table 2: Adverse reactions associated with Atripla listed by the component(s) of Atripla to which the adverse reactions are attributable
Danish: Tabel 2: Bivirkninger som er forbundet med Atripla, opstillet efter den Atripla-komponent, som bivirkningen kan tilskrives.
English: In patients with advanced liver disease or cirrhosis, treatment discontinuation is not recommended since post-treatment exacerbation of hepatitis may lead to hepatic decompensation.
Danish: Behandlingen bør ikke seponeres hos patienter med fremskreden leversygdom eller levercirrose, da forværringen efter behandlingsophør kan føre til hepatisk dekompensation.
English: Co-administration with terfenadine, astemizole, cisapride, midazolam, triazolam, pimozide, bepridil, or ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine).
Danish: Samtidig administration med terfenadin, astemizol, cisaprid, midazolam, triazolam, primozid, bepridil eller ergotalkaloider (f.eks. ergotamin, dihydroergotamin, ergonovin og methylergonovin).
English: Artemether/Lumefantrine/Efavirenz (20/120 mg tablet, 6 doses of 4 tablets each over 3 days/600 mg q.d.)
Danish: Midler mod malaria Artemether/lumefantrin/efavirenz (20/120 mg tablet, 6 doser hver med 4 tabletter i 3 dage/600 mg q.d.)
English: Barrier contraception should always be used in combination with other methods of contraception (for example, oral or other hormonal contraceptives, see section 4.5) while on therapy with Atripla.
Danish: Barrierekontraception bør altid anvendes sammen med andre kontraceptiva (f.eks. orale eller andre hormonkontraceptiva, se pkt.
English: Posaconazole:
Danish: Posaconazol:
English: If the patient vomits more than 1 hour after taking Atripla he/she does not need to take another dose.
Danish: Hvis patienten kaster op mere end 1 time efter at have taget Atripla, skal patienten ikke tage en ny dosis.
English: Atripla and vigabatrin or gabapentin can be coadministered without dose adjustment.
Danish: Atripla og vigabatrin eller gabapentin kan administreres samtidigt uden dosisjustering.
English: Co-administration of simeprevir with Atripla is not recommended.
Danish: Samtidig administration af simeprevir og Atripla frarådes.
English: Renal and urinary disorders: Uncommon increased creatinine, proteinuria, proximal renal tubulopathy including Fanconi syndrome
Danish: Forhøjet kreatinin, proteinuri, proksimal renal tubulopati herunder Fanconis syndrom
English: Tenofovir disoproxil and emtricitabine, two of the active substances in Atripla, show some activity against hepatitis B virus although emtricitabine is not approved for the treatment of hepatitis B infection.
Danish: Hvis De har en hepatitis B-infektion, vil Deres læge nøje overveje, hvilken behandling, der er den bedste for Dem. Tenofovirdisoproxil og emtricitabin, to af de aktive stoffer i Atripla, har en vis virkning mod hepatitis B-virus, selvom emtricitabin ikke er godkendt til behandling af hepatitis B-infektion.
English: Carcinogenicity studies in male mice, male and female rats were negative.
Danish: Karcinogenicitetsstudier i hanmus samt han- og hunrotter var negative.
English: -0.5% (-3.2% to 2.2%)
Danish: -0,5% (-3,2% til 2,2%)
English: Atovaquone and proguanil hydrochloride/Emtricitabine
Danish: Atovaquon og proguanilhydrochlorid/emtricitabin
English: genotype following the administration of 600 mg daily dose for 14 days was 2.25-fold the mean Cmax observed in subjects with CYP2B6 *1/*1 genotype.
Danish: Middel Cmax for efavirenz hos forsøgspersoner med CYP2B6 *6/*6 genotype efter administration af en daglig dosis på 600 mg i 14 dage var 2,25 gange middel Cmax, der sås hos forsøgspersoner med CYP2B6 *1/*1 genotype.
English: Discontinuation of Atripla therapy in patients co-infected with HIV and HBV may be associated with severe acute exacerbations of hepatitis.
Danish: Seponering af Atripla hos patienter, der har både hiv og HBV, kan være forbundet med svær, akut forværring af hepatitis.
English: Due to the similarity between lamivudine and emtricitabine, a component of Atripla, Atripla should not be administered concomitantly with lamivudine (see section 4.4).
Danish: Grundet ligheden mellem lamivudin og emtricitabin, en Atripla-komponent, bør Atripla ikke gives samtidigt med lamivudin (se pkt.
English: Concomitant administration of Atripla and sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/ voxilaprevir is expected to decrease plasma concentrations of velpatasvir and voxilaprevir.
Danish: Samtidig administration af Atripla og sofosbuvir/velpatasvir eller sofosbuvir/velpatasvir/ voxilaprevir forventes at reducere plasmakoncentrationen af velpatasvir og voxilaprevir.
English: As a fixed combination, Atripla should not be administered concomitantly with other medicinal products containing the components, emtricitabine or tenofovir disoproxil.
Danish: Som en fast kombination bør Atripla ikke administreres samtidigt med andre lægemidler, der indeholder komponenterne emtricitabin eller tenofovirdisoproxil.
English: Clarithromycin/Emtricitabine
Danish: Clarithromycin/emtricitabin
English: Itraconazole:
Danish: Itraconazol:
English: Elbasvir/grazoprevir: Co-administration of Atripla with elbasvir/grazoprevir is contraindicated because it may lead to loss of virologic response to elbasvir/grazoprevir (see section 4.3 and Table 1).
Danish: Elbasvir/grazoprevir: Samtidig administration af Atripla med elbasvir/grazoprevir er kontraindiceret, da det kan medføre tab af det virologiske respons på elbasvir/grazoprevir (se pkt.
English: Monitoring of renal function is recommended for patients receiving Atripla (see section 4.4).
Danish: Nyrefunktionen bør monitoreres hos patienter, som får Atripla (se pkt.
English: (CYP3A4 or P-gp induction - effect on elbasvir)
Danish: (CYP3A4 eller P-gp-induktionvirkning på elbasvir)
English: 0.5% (-7.0% to 9.3%)
Danish: 0,5% (-7,0% til 9,3%)
English: Tenofovir disoproxil:
Danish: Tenofovirdisoproxil:
English: AUC: ↔ Cmax: ↓ 19% (↓ 40 to ↑ 10)
Danish: AUC: ↔ Cmax: ↓ 19% (↓ 40 til ↑ 10)
English: Cmax: ↑ 11% (↑ 6 to ↑ 16) Cmin: ↔
Danish: Cmax: ↑ 11% (↑ 6 til ↑ 16) Cmin: ↔
English: However, dizziness has been reported during treatment with efavirenz, emtricitabine and tenofovir disoproxil.
Danish: Der er imidlertid rapporteret om svimmelhed under behandling med efavirenz, emtricitabin og tenofovirdisoproxil.
English: AUC: ↔* (↓ 9% to ↑ 10%) Cmax: ↑ 17%* (↑ 8 to ↑ 27) Cmin: ↓ 42%* (↓ 31 to ↓ 51)
Danish: AUC: ↔* (↓ 9% til ↑ 10%) Cmax: ↑ 17%* (↑ 8 til ↑ 27) Cmin: ↓ 42%* (↓ 31 til ↓ 51)
English: Implant: Etonogestrel/Efavirenz
Danish: Implantat: Etonogestrel/efavirenz
English: (CYP3A4 induction) For co-administration of efavirenz with low-dose ritonavir in combination with a protease inhibitor, see section on ritonavir below.
Danish: (CYP3A4-induktion) Mht. samtidig administration af efavirenz og lav-dosis ritonavir i kombination med en proteasehæmmer se afsnittet om ritonavir nedenfor.
English: Mechanism of action and pharmacodynamic effects Efavirenz is an NNRTI of HIV-1.
Danish: Efavirenz er en NNRTI af hiv-1.
English: Simeprevir/Emtricitabine
Danish: Simeprevir/emtricitabin
English: QTc prolongation has been observed with the use of efavirenz (see sections 4.5 and 5.1).
Danish: Der er set QTc-forlængelse i forbindelse med brug af efavirenz (se pkt.
English: There were no clinically significant pharmacokinetic interactions when emtricitabine was administered with stavudine, zidovudine or famciclovir.
Danish: Der var ingen klinisk signifikante farmakokinetiske interaktioner, når emtricitabin blev administreret sammen med stavudin, zidovudin eller famciclovir.
English: AUC: ↔ Cmax: ↑ 50% (↑ 20 to ↑ 80)
Danish: AUC: ↔ Cmax: ↑ 50% (↑ 20 til ↑ 80)
English: Posaconazole/Efavirenz (-/400 mg q.d.)
Danish: Posaconazol/efavirenz (-/400 mg q.d.)
English: Each film-coated tablet contains 1 mmol (23.6 mg) of sodium.
Danish: Hjælpestof, som behandleren skal være opmærksom på Hver filmovertrukken tablet indeholder 1 mmol (23,6 mg) natrium.
English: While taking Atripla you may still develop infections or other illnesses associated with HIV infection.
Danish: De kan stadig få infektioner eller andre sygdomme, der er forbundet med hiv-infektion, selvom De tager Atripla.
English: Lopinavir/ritonavir soft capsules or oral solution/Efavirenz
Danish: Lopinavir/ritonavir bløde kapsler eller oral opløsning/efavirenz
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Danish: Stivhed, ømhed og smerter i ledene (især i hofte, knæ og skulder) samt bevægelsesbesvær er tegn på knoglenekrose.
English: Co-administration of efavirenz with atazanavir/ritonavir is not recommended.
Danish: Samtidig administration af efavirenz og atazanavir/ritonavir frarådes.
English: When Atripla is coadministered with an anticonvulsant that is a substrate of CYP isozymes, periodic monitoring of anticonvulsant levels should be conducted.
Danish: Når Atripla administreres sammen med et krampestillende lægemiddel, som er et substrat for CYPisozymer, bør monitorering af de krampestillende koncentrationer foretages.
English: -0.5% (-7.6% to 7.9%)
Danish: -0,5% (-7,6% til 7,9%)
English: AUC: ↓ 31% (↓ 8 to ↓ 47) Cmin: ↓ 40%
Danish: AUC: ↓ 31% (↓ 8 til ↓ 47) Cmin: ↓ 40%
English: AUC: ↑ 34% (↑ 18 to ↑ 53) Cmax: ↑ 49% (↑ 32 to ↑ 69)
Danish: AUC: ↑ 34% (↑ 18 til ↑ 53) Cmax: ↑ 49% (↑ 32 til ↑ 69)
English: Skin and subcutaneous tissue disorders: Very common rash (moderate-severe, 11.6%, all grades, 18%)3
Danish: Udslæt (moderat-svær 11,6%, alle grader
English: Your doctor may need to consider giving you a different antifungal.
Danish: Deres læge kan finde det nødvendigt at overveje at give Dem et andet svampemiddel.
English: AUC: ↔ Cmax: ↑ 11% (↑ 3 to ↑ 19)
Danish: AUC: ↔ Cmax: ↑ 11% (↑ 3 til ↑ 19)
English: AUC: ↓ 43% (↓ 7 to ↓ 65) Cmax: ↔
Danish: AUC: ↓ 43% (↓ 7 til ↓ 65) Cmax: ↔
English: Morning Cmin: ↑ 42% (↑ 9 to ↑ 86) Evening Cmin: ↑ 24% (↑ 3 to ↑ 50)
Danish: Cmin morgen: ↑ 42% (↑ 9 til ↑ 86) Cmin aften: ↑ 24% (↑ 3 til ↑ 50)
English: AUC: ↔ Cmax: ↓ 23% (↓ 30 to ↑ 16)
Danish: AUC: ↔ Cmax: ↓ 23% (↓ 30 til ↑ 16)
English: Insufficient data are available to make a dosing recommendation for saquinavir/ritonavir when dosed with Atripla.
Danish: Kun utilstrækkelige data er tilgængelige til en doseringsanbefaling for saquinavir/ritonavir, når dette doseres sammen med Atripla.
English: Patients with renal impairment: Since tenofovir disoproxil can cause renal toxicity, close monitoring of renal function is recommended in any patient with mild renal impairment treated with Atripla (see sections 4.2, 4.4 and 5.2).
Danish: Patienter med nedsat nyrefunktion: Da tenofovirdisoproxil kan forårsage nyretoksicitet, anbefales tæt monitorering af nyrefunktionen hos alle patienter med let nedsat nyrefunktion, som behandles med Atripla (se pkt.
English: Your doctor may give you a different anticonvulsant.
Danish: Lægen kan give Dem et andet krampestillende lægemiddel.
English: Etonogestrel/Emtricitabine
Danish: Etonogestrel/emtricitabin
English: Atripla is not recommended for patients with moderate or severe renal impairment (creatinine clearance < 50 ml/min).
Danish: Atripla frarådes til patienter med moderat eller svær nedsat nyrefunktion (kreatininclearance < 50 ml/min).
English: (CYP3A4 or P-gp induction - effect on grazoprevir)
Danish: (CYP3A4 eller P-gp-induktionvirkning på grazoprevir)
English: Buprenorphine/naloxone/Efavirenz
Danish: Buprenorphin/naloxon/efavirenz
English: Metabolism and nutrition disorders: Very common hypophosphataemia2
Danish: Overfølsomhed Metabolisme og ernæring: Meget almindelig
English: Common pruritus vesiculobullous rash, pustular rash, maculopapular rash, rash, pruritus, urticaria, skin discolouration (increased pigmentation)1
Danish: Vesikuløst udslæt, pustuløst udslæt, makulopapuløst udslæt, udslæt, pruritus, urticaria, misfarvning af huden (øget pigmentering)1
English: There were no clinically significant pharmacokinetic interactions when tenofovir disoproxil was co-administered with emtricitabine, nelfinavir or ribavirin.
Danish: Der var ingen klinisk signifikante farmakokinetiske interaktioner, når tenofovirdisoproxil blev administreret sammen med emtricitabin, nelfinavir eller ribavirin.
English: • angry behaviour, suicidal thoughts, strange thoughts, paranoia, unable to think clearly, mood being affected, seeing or hearing things that are not really there (hallucinations), suicide attempts, personality change (psychosis), catatonia (a condition in which the patient is rendered motionless and speechless for a period).
Danish: selvmordsforsøg, personlighedsændring (psykoser), katatoni (en tilstand, hvor patienten ikke kan bevæge sig eller tale i et stykke tid).
English: Interaction not studied with efavirenz, emtricitabine, or tenofovir disoproxil.
Danish: Interaktion er ikke undersøgt med efavirenz, emtricitabin eller tenofovirdisoproxil.
English: Atovaquone and proguanil hydrochloride/Efavirenz (250/100 mg single dose/600 mg q.d.)
Danish: Atovaquon og proguanilhydrochlorid/efavirenz (250/100 mg enkeltdosis/600 mg q.d.)
English: Maraviroc/Emtricitabine
Danish: Maraviroc/emtricitabin
English: AUC: ↔ Cmax: ↑ 38% (↑ 14 to ↑ 67)
Danish: AUC: ↔ Cmax: ↑ 38% (↑ 14 til ↑ 67)
English: - Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) - Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) - Tenofovir is a nucleotide reverse transcriptase inhibitor (NtRTI)
Danish: - Efavirenz er en ikke-nukleosid-revers transkriptase-hæmmer (NNRTI).
English: For co-administration of efavirenz with low-dose ritonavir in combination with a protease inhibitor, see section on ritonavir above.
Danish: Mht. samtidig administration af efavirenz og lav-dosis ritonavir i kombination med en proteasehæmmer se afsnittet om ritonavir ovenfor.
English: Co-administration of Atripla and sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/voxilaprevir is not recommended since plasma concentrations of velpatasvir and voxilaprevir are expected to decrease following co-administration with efavirenz leading to reduced therapeutic effect of sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/voxilaprevir (see section 4.5).
Danish: Samtidig administration af Atripla og sofosbuvir/velpatasvir eller sofosbuvir/velpatasvir/voxilaprevir frarådes, da plasmakoncentrationen af velpatasvir og voxilaprevir forventes at blive reduceret efter samtidig administration af efavirenz, som kan resultere i manglende terapeutisk virkning af sofosbuvir/velpatasvir eller sofosbuvir/velpatasvir/voxilaprevir (se pkt.
English: Ethinyloestradiol+Norgestimate/Efavirenz (0.035 mg+0.25 mg q.d./600 mg q.d.)
Danish: Ethinylestradiol+norgestimat/efavire nz (0,035 mg+0,25 mg q.d./600 mg q.d.)
English: The pharmacokinetics of efavirenz have not been studied in patients with renal impairment.
Danish: Efavirenz' farmakokinetik er ikke undersøgt hos patienter med nedsat nyrefunktion.
English: Raltegravir/Emtricitabine
Danish: Raltegravir/emtricitabin
English: AUC: ↔*/** (↓ 10% to ↑ 26%) Cmax: ↔*/** (↓ 5% to ↑ 26%) Cmin: ↑ 12%*/** (↓ 16 to ↑ 49)
Danish: AUC: ↔*/** (↓ 10% til ↑ 26%) Cmax: ↔*/** (↓ 5% til ↑ 26%) Cmin: ↑ 12%*/** (↓ 16 til ↑ 49) (CYP3A4-induktion).
English: Cmax: ↓ 28% (↓ 7 to ↓ 44) Cmin: ↓ 37% (↓ 17 to ↓ 52)
Danish: Cmax: ↓ 28% (↓ 7 til ↓ 44) Cmin: ↓ 37% (↓ 17 til ↓ 52)
English: Artemether/Lumefantrine/Tenofovir disoproxil
Danish: Artemether/lumefantrin/ tenofovirdisoproxil
English: Diltiazem/Emtricitabine
Danish: Diltiazem/emtricitabin
English: • loss of appetite
Danish: • Appetitløshed
English: They usually begin during the first one or two days of efavirenz therapy and generally resolve after the first two to four weeks.
Danish: De debuterer sædvanligvis i løbet af de første 1-2 behandlingsdage med efavirenz og forsvinder i reglen efter de første 2-4 uger.
English: Pink, capsule-shaped, film-coated tablet, of dimensions 20 mm x 10.4 mm, debossed with “123” on one side, plain on the other side.
Danish: Lyserød, kapselformet, filmovertrukken tablet, der måler 20 mm x 10,4 mm.
English: Rarely, pancreatitis and lactic acidosis, sometimes fatal have been reported.
Danish: Der er rapporteret sjældne tilfælde af pancreatitis og laktatacidose, og nogle af disse tilfælde var letale.
English: Due to similarities with emtricitabine, Atripla should not be administered concomitantly with other cytidine analogues, such as lamivudine (see section 4.5).
Danish: På grund af ligheder med emtricibatin bør Atripla ikke gives samtidigt med andre cytidinanaloger som lamivudin (se pkt.
English: Recommendation concerning co-administration with Atripla (efavirenz 600 mg, emtricitabine 200 mg, tenofovir disoproxil 245 mg)
Danish: samtidig administration af Atripla (efavirenz 600 mg, emtricitabin 200 mg, tenofovirdisoproxil245 mg)
English: Atripla can reduce the amount of the anticonvulsant in your blood.
Danish: Atripla kan nedsætte mængden af den krampestillende medicin i blodet.
English: Since Atripla is a fixed-dose combination product, the dose of efavirenz cannot be altered; therefore, voriconazole and Atripla must not be co-administered (see section 4.3 and Table 1).
Danish: Da Atripla er et fastdosis-kombinationsprodukt, kan efavirenzdosis ikke ændres; voriconazol og Atripla må derfor ikke administreres samtidigt (se pkt.
English: If a patient is already taking St. John's wort, stop St. John's wort, check viral levels and if possible efavirenz levels.
Danish: Hvis en patient allerede tager perikon, skal dette middel seponeres, og de virale koncentrationer og om muligt efavirenzkoncentrationerne skal kontrolleres.
English: Vigabatrin/Tenofovir disoproxil Gabapentin/Tenofovir disoproxil
Danish: Vigabatrin/tenofovirdisoproxil Gabapentin/tenofovirdisoproxil
English: If overdose occurs, the patient must be monitored for evidence of toxicity (see section 4.8), and standard supportive treatment applied as necessary.
Danish: Hvis overdosering forekommer, skal patienten monitoreres med henblik på tegn på toksicitet (se pkt.
English: There have been reports of mitochondrial dysfunction in HIV negative infants exposed in utero and/or postnatally to nucleoside analogues; these have predominantly concerned treatment with regimens containing zidovudine.
Danish: Der er rapporteret om mitokondriel dysfunktion hos hiv-negative spædbørn, som har været eksponeret for nukleosidanaloger in utero og/eller postnatalt.
English: Norgestimate/Ethinyloestradiol/ Emtricitabine
Danish: Norgestimat/ethinylestradiol/ emtricitabin
English: • dizziness, headache, diarrhoea, feeling sick (nausea), being sick (vomiting)
Danish: • Svimmelhed, hovedpine, diarré, kvalme, opkastning
English: AUC: ↓ 40% (↓ 26 to ↓ 57) Cmax: ↓ 18% (↓ 59 to ↑ 12)
Danish: AUC: ↓ 40% (↓ 26 til ↓ 57) Cmax: ↓ 18% (↓ 59 til ↑ 12)
English: Norepinephrine and dopamine reuptake inhibitor Bupropion/Efavirenz [150 mg single dose (sustained release)/600 mg q.d.]
Danish: Noradrenalin- og dopamin-reuptake-hæmmer Bupropion/efavirenz [150 mg enkeltdosis (protraheret frigivelse)/600 mg q.d.]