FrancophonIA/ELRC3.0 huggingface dataset:
English: Broadline was 100% effective against the L4 larval stage of heartworm.
Slovenian: Zdravilo Broadline je bilo 100-odstotno učinkovito proti stadiju L4 ličinke srčne gliste.
English: People with known hypersensitivity to any of the ingredients should avoid contact with the product.
Slovenian: Osebe z znano preobčutljivostjo za katero koli sestavino zdravila naj se izogibajo stiku z njim.
English: What is Broadline and what is it used for?
Slovenian: Kaj je zdravilo Broadline in za kaj se uporablja?
English: This means that they kill external parasites that live on the skin or in the fur of animals, such as fleas and ticks.
Slovenian: To pomeni, da uničita zunanje parazite, ki živijo na koži ali dlaki živali, kot so bolhe in klopi.
English: It may also be used as part of a treatment strategy for flea allergy dermatitis (an allergic reaction to flea bites).
Slovenian: Uporablja se lahko tudi kot del strategije zdravljenja alergijskega dermatitisa, ki ga povzročajo bolhe (alergijske reakcije na ugrize bolh).
English: What benefits of Broadline have been shown in studies?
Slovenian: Kakšne koristi je zdravilo Broadline izkazalo v študijah?
English: If the cat licks the application site, temporary excessive salivation may occur.
Slovenian: Če mačka liže mesto nanosa, se lahko pojavi začasno čezmerno slinjenje.
English: For more information about using Broadline, see the package leaflet or contact your veterinarian or pharmacist.
Slovenian: Za več informacij glede uporabe zdravila Broadline glejte navodilo za uporabo ali se posvetujte z veterinarjem ali farmacevtom.
English: If a cat swallows the medicine, it may result in vomiting (being sick) and/or short-lived effects on the nervous system, shown by signs such as lack of muscular coordination, disorientation, lack of interest in surroundings and pupil dilation.
Slovenian: Če mačka zdravilo zaužije, lahko to povzroči bruhanje (slabost) in/ali kratkotrajne učinke na živčevje, ki se kažejo z znaki, kot so odsotnost mišične koordinacije, izguba orientacije, zmanjšanje zanimanja za okolico in razširjene zenice.
English: Broadline (fipronil/(S)methoprene/eprinomectin/praziquantel)
Slovenian: Broadline (fipronil/(S)metopren/eprinomektin/prazikvantel)
English: The measure of effectiveness was reduction of the number of Notoedres cati mites found in skin scrapings compared to cats that received no treatment.
Slovenian: Merilo učinkovitosti je bilo zmanjšanje števila srbcev rodu Notoedres cati, najdenih v odluščeni koži, v primerjavi s številom srbcev pri mačkah, ki niso prejemale zdravljenja.
English: For external parasites, Broadline treats flea infestations and prevents new infestations for at least one month; it also prevents environmental flea contamination for over a month.
Slovenian: V zvezi z zunanjimi paraziti zdravilo Broadline zdravi infestacije z bolhami in preprečuje pojav novih še vsaj en mesec; prav tako več kot mesec dni preprečuje kontaminacijo okolja z bolhami.
English: The study showed over 98% effectiveness of the medicine against the mite, with a clinical cure in all animals.
Slovenian: Študija je pokazala več kot 98-odstotno učinkovitost zdravila proti garjam s klinično ozdravitvijo pri vseh živalih
English: Effectiveness was measured by identifying adult worm segments (tapeworms) or counting worm eggs (roundworms) in faeces at day 14 after treatment.
Slovenian: Učinkovitost so merili z ugotavljanjem segmentov odraslih črvov (trakulj) ali štetjem jajčec črvov (valjastih črvov) v blatu 14. dan po zdravljenju.
English: For lungworm a second treatment may be recommended one month after the initial treatment.
Slovenian: V primeru pljučnih glist se priporoča ponovitev zdravljenja en mesec po prvotnem nanosu zdravila.
English: (S)-methoprene is an insect growth regulator which stops the flea life cycle by killing eggs and blocking the development of juvenile flea stages and causing their death.
Slovenian: (S)-metopren je sredstvo za uravnavanje rasti žuželk, ki zaustavi življenjski cikel bolh tako, da uniči njihova jajčeca in zavira razvoj nezrelih bolh, kar povzroči njihov pogin.
English: For ticks, effectiveness was between 85 and 93% for Broadline-treated cats compared with 92 and 98% for cats treated with the comparator product.
Slovenian: Pri klopih je bila učinkovitost zdravila Broadline med 85- in 93-odstotna v primerjavi z med 92- in 98-odstotno učinkovitostjo pri mačkah, zdravljenih s primerjalnim zdravilom.
English: Broadline was more than 90% effective in reducing lungworm larvae at 28 days after treatment and all treated cats showing respiratory signs (such as wheezing, persistent coughing and a runny nose) were clinically cured.
Slovenian: Zdravilo Broadline je pokazalo več kot 90-odstotno učinkovitost pri zmanjšanju števila ličink pljučnih glist na 28. dan po zdravljenju, vse zdravljene mačke, ki so kazale simptome težav z dihali (sopihanje, trdovraten kašelj in izcedek iz nosu), so bile klinično ozdravljene.
English: Praziquantel acts on the cell membranes of tapeworms, leading to the death of the parasite.
Slovenian: Prazikvantel učinkuje na celične membrane trakulj in s tem povzroči smrt parazita.
English: The main measure of effectiveness was reduction of numbers of worm larvae in faeces at 28 days after single treatment.
Slovenian: Glavno merilo učinkovitosti je bilo zmanjšanje števila ličink gliste v izločkih na 28. dan po enkratnem zdravljenju.
English: The study showed effectiveness of 86 to 87% against adult fleas for Broadline throughout the 30 day post-treatment period compared with between 76 and 82% for cats treated with another medicine containing just fipronil and (S)-methoprene.
Slovenian: Študija v EU je pokazala med 86- in 87-odstotno učinkovitost zdravila Broadline proti odraslim bolham v celotnem tridesetdnevnem obdobju po uporabi zdravila v primerjavi z med 76- in 82-odstotno učinkovitostjo pri mačkah, zdravljenih z drugim zdravilom, ki je vsebovalo samo fipronil in (S)-metopren.
English: It blocks channels in their nerve cells that allow charged chloride particles (ions) to pass, interfering with the transmission of nerve signals and leading to overstimulation and death.
Slovenian: Zavira kanalčke v njihovih živčnih celicah, ki omogočajo prehod nabitih kloridnih delcev (ionov), to pa ovira prenos živčnih signalov in povzroči čezmerno stimulacijo in pogin.
English: How does Broadline work?
Slovenian: Kako zdravilo Broadline deluje?
English: If eye irritation persists, or if side effects are noticed, medical advice should be sought and the package leaflet or label shown to the doctor.
Slovenian: Če draženje očesa ne preneha ali če opazite neželene učinke, se morate posvetovati z zdravnikom in mu pokazati navodilo za uporabo ali nalepko zdravila.
English: The effectiveness of Broadline to prevent heartworm disease was shown in three laboratory studies, using artificially infected cats.
Slovenian: Učinkovitost zdravila Broadline pri preprečevanju okužbe s srčnimi glistami so dokazali v treh laboratorijskih študijah, v katere so bile vključene umetno okužene mačke.
English: How is Broadline used?
Slovenian: Kako se zdravilo Broadline uporablja?
English: The other two active substances in Broadline, eprinomectin and praziquantel, act as ‘endoparasiticides'.
Slovenian: Drugi dve učinkovini v zdravilu Broadline, eprinomektin in prazikvantel, delujeta kot „endoparaziticida“.
English: The effectiveness of Broadline against feline lungworm was investigated in a field study in Italy.
Slovenian: Učinkovitost zdravila Broadline proti mačji pljučni glistavosti so proučevali v terenski študiji v Italiji.
English: It treats tick infestations and prevents new infestations for up to three weeks.
Slovenian: Zdravilo Broadline zdravi infestacije s klopi in največ tri tedne preprečuje nove infestacije.
English: Broadline is available as a spot-on solution in applicators of two different volume sizes for use in cats of various bodyweights and can only be obtained with a prescription.
Slovenian: Zdravilo Broadline je na voljo v obliki raztopine za kožni nanos v aplikatorjih dveh različnih volumnov za uporabo pri mačkah z različno telesno maso, njegovo predpisovanje in izdaja pa je le na recept.
English: Mild and short-lived skin reactions (itching, hair loss) may occur at the application site.
Slovenian: Na mestu nanosa se lahko pojavijo blage in kratkotrajne kožne reakcije (srbenje, izpadanje dlake).
English: The effectiveness of Broadline against cat mange was examined in a laboratory study with 18 naturally infested cats.
Slovenian: Učinkovitost zdravila Broadline proti mačjim garjam je bila proučena v laboratorijski študiji, ki je zajela 18 naravno okuženih mačk.
English: Broadline-treated cats were compared to cats treated with a spot-on product containing the worm medicines emodepside and praziquantel.
Slovenian: Mačke, zdravljene z zdravilom Broadline, so primerjali z mačkami, zdravljenimi z zdravilom za kožni nanos, ki je vsebovalo učinkovini proti črvom, imenovani emodepsid in prazikvantel.
English: Broadline contains four active substances: fipronil, (S)-methoprene, eprinomectin and praziquantel.
Slovenian: Zdravilo Broadline vsebuje štiri učinkovine: fipronil, (S)-metopren, eprinomektin in prazikvantel.
English: The effectiveness of Broadline against fleas and ticks was investigated in an EU field study involving cats infested with fleas, ticks, or both.
Slovenian: Učinkovitost zdravila Broadline proti bolham in klopom so proučevali v terenski študiji v EU, ki je zajela mačke, infestirane z bolhami, klopi ali obojim.
English: Broadline is a veterinary medicine used to treat cats with, or at risk of, mixed infestations by tapeworms, roundworms and external parasites (fleas, ticks, and a burrowing mite called Notoedres cati which is a cause of mange).
Slovenian: Broadline je zdravilo za uporabo v veterinarski medicini, ki se uporablja za zdravljenje mačk z mešanimi infestacijami s trakuljami, valjastimi črvi in zunanjimi paraziti (bolhami, klopi, srbci iz rodu Notoedres cati, ki povzročajo garje) oziroma mačk, ki so izpostavljene temu tveganju.
English: Eprinomectin interferes with channels in the nerve and muscle cells of roundworms that allow charged chloride particles (ions) to pass, leading to their paralysis and death.
Slovenian: Eprinomektin zavira kanalčke v živčnih in mišičnih celicah valjastih črvov, kar prepreči prehod nabitih kloridnih delcev (ionov) in posledično povzroči paralizo ter pogin.
English: Twenty cats naturally infested with lungworm were treated with Broadline.
Slovenian: Z zdravilom Broadline so zdravili dvajset mačk, naravno okuženih s pljučnimi glistami.
English: The effectiveness of Broadline against intestinal worms was investigated in one EU field study involving cats with tapeworm, roundworm or hookworm infections or mixed infections.
Slovenian: Učinkovitost zdravila Broadline proti črevesnim črvom so proučevali v eni terenski študiji v EU, ki je zajela mačke, infestirane s trakuljami, valjastimi črvi ali kavljastimi črvi ali mešanimi infestacijami.
English: Two of the active substances in Broadline, fipronil and (S)-methoprene, act as ‘ectoparasiticides'.
Slovenian: Dve učinkovini v zdravilu Broadline, fipronil in (S)-metopren, delujeta kot „ektoparaziticida“.
English: Broadline can also be used to prevent heartworm disease for one month.
Slovenian: Prav tako se lahko uporablja za enomesečno preprečevanje srčne glistavosti.
English: For worms, Broadline is used to treat tapeworms, roundworms and hookworms in the gut as well as a type of worm that infects the bladder and two types of feline lungworm.
Slovenian: Pri zdravljenju infestacij s črvi se zdravilo Broadline uporablja za odpravljanje infestacij s trakuljami, valjastimi črvi in kavljastimi črvi v črevesju ter vrsto črvov, ki napade sečni mehur, in dvema vrstama mačjih pljučnih glist.
English: The content of one full applicator (appropriate to the cat's weight) is applied directly to the cat's skin after parting the hair, in a single spot on the middle of the neck.
Slovenian: Najprej je treba razmakniti dlako na enem mestu na sredi mačkinega vratu, potem pa vsebino enega polnega aplikatorja (ki ustreza telesni masi mačke) nanesti neposredno na kožo.
English: The study showed almost 100% effectiveness against tapeworms, roundworms and hookworms for both Broadline and the comparator product.
Slovenian: Študija je pokazala skoraj 100-odstotno učinkovitost zdravila Broadline ter primerjalnega zdravila proti trakuljam, valjastim črvom in kavljastim črvom.
English: Docefrez docetaxel
Slovenian: Docefrez docetaksel
English: What are the benefit and risk of Docefrez?
Slovenian: Kakšne so koristi in tveganja, povezani z zdravilom Docefrez?
English: Docefrez is only used when the neutrophil count (the level of a type of white blood cell in the blood) is normal (at least 1,500 cells/mm3).
Slovenian: Zdravilo Docefrez se uporablja le, kadar je število nevtrofilcev (raven vrste belih krvnih celic v krvi) normalno (vsaj 1 500 celic/mm3).
English: This means that Docefrez is similar to a ‘reference medicine' already authorised in the European Union (EU) called Taxotere.
Slovenian: To pomeni, da je podobno „referenčnemu zdravilu“, ki je že odobreno v Evropski uniji (EU), in sicer zdravilu Taxotere.
English: Other information about Docefrez:
Slovenian: Druge informacije o zdravilu Docefrez:
English: Docefrez is given as a one-hour infusion every three weeks.
Slovenian: Zdravilo Docefrez se daje v obliki enourne infuzije vsake tri tedne.
English: Docetaxel blocks the ability of cells to destroy the internal ‘skeleton' that allows them to divide and multiply.
Slovenian: Docetaksel zavira sposobnost celic za razkrajanje svojega notranjega „skeleta“, ki jim omogoča delitev in razmnoževanje.
English: • prostate cancer, when the cancer does not respond to hormonal treatment.
Slovenian: • raka prostate, če je rak neodziven na hormonsko zdravljenje.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Docefrez to Sun Pharmaceutical Industries Europe B.V. on 15 May 2010.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Docefrez, veljavno po vsej Evropski uniji, odobrila družbi Sun Pharmaceutical Industries Europe B.V.
English: This document is a summary of the European Public Assessment Report (EPAR) for Docefrez.
Slovenian: Ta dokument je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Docefrez.
English: Docefrez is a ‘generic medicine'.
Slovenian: Zdravilo Docefrez je „generično zdravilo“.
English: Docefrez is used to treat the following types of cancer:
Slovenian: Zdravilo Docefrez se uporablja za zdravljenje naslednjih vrst raka:
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Docefrez.
Slovenian: Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil zdravilo Docefrez, na podlagi česar je oblikoval mnenje za odobritev dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
English: Docefrez can be used on its own after other treatments have failed.
Slovenian: Zdravilo Docefrez se lahko uporablja samostojno po neuspešnem zdravljenju z drugimi zdravili.
English: Because Docefrez is a generic medicine, the company provided data on docetaxel from the published literature.
Slovenian: Ker je zdravilo Docefrez generično zdravilo, je družba predložila podatke o docetakselu iz objavljene literature.
English: For more information, see the Summary of Product Characteristics.
Slovenian: Za več informacij glejte povzetek glavnih značilnosti zdravila.
English: Docetaxel also affects non-cancer cells such as blood cells, which can cause side effects.
Slovenian: Docetaksel vpliva tudi na nerakave celice, kot so krvne celice, kar lahko povzroči neželene učinke.
English: The full EPAR for the reference medicine can also be found on the Agency's website.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za referenčno zdravilo je na voljo na spletni strani Agencije.
English: Docefrez is used with cisplatin and 5-fluorouracil.
Slovenian: Zdravilo Docefrez se uporablja s cisplatinom in 5-fluorouracilom.
English: For full details, see the Summary of Product Characteristics (also part of the EPAR).
Slovenian: Za podrobnejše informacije glejte povzetek glavnih značilnosti zdravila (ki je prav tako del EPAR).
English: The Committee recommended that Docefrez be given marketing authorisation.
Slovenian: Odbor je priporočil odobritev dovoljenja za promet z zdravilom Docefrez.
English: Therefore, the CHMP's view was that, as for Taxotere, the benefit outweighs the identified risk.
Slovenian: Zato je CHMP menil, da koristi zdravila Taxotere odtehtajo znana tveganja.
English: For more information about treatment with Docefrez, read the Package Leaflet (also part of the EPAR).
Slovenian: Za več informacij o zdravljenju z zdravilom Docefrez preberite navodilo za uporabo (ki je prav tako del EPAR).
English: • non-small cell lung cancer.
Slovenian: • nedrobnoceličnega raka pljuč.
English: It can also be used with other anticancer medicines (doxorubicin, cyclophosphamide, trastuzumab or capecitabine) in patients who have not yet received any treatment for their cancer or after other treatments have failed, depending on the type and stage of the breast cancer being treated;
Slovenian: Uporablja se lahko tudi z drugimi zdravili proti raku (doksorubicinom, ciklofosfamidom, trastuzumabom ali kapecitabinom) pri bolnikih, ki se še niso zdravili ali pa je bilo zdravljenje neuspešno, odvisno od vrste in stadija raka dojke, ki se zdravi;
English: Dexamethasone (an anti-inflammatory medicine) should also be given to the patient, starting on the day before the Docefrez infusion.
Slovenian: Bolniku je treba dati tudi deksametazon (protivnetno zdravilo), in sicer dan pred infuzijo zdravila Docefrez.
English: • gastric adenocarcinoma (a type of stomach cancer) in patients who have not yet received any treatment for their cancer.
Slovenian: • adenokarcinoma želodca (vrsta raka želodca) pri bolnikih, ki se še niso zdravili.
English: The CHMP concluded that, in accordance with EU requirements, Docefrez has been shown to be comparable to Taxotere.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) je zaključil, da je bila v skladu z zahtevami EU dokazana primerljivost zdravila Docefrez in zdravila Taxotere.
English: Docefrez should be used in wards specialising in chemotherapy (using medicines to treat cancer) under the supervision of a doctor who is qualified in the use of chemotherapy.
Slovenian: Zdravilo Docefrez je treba uporabljati na specializiranih oddelkih za kemoterapijo (na katerih uporabljajo zdravila proti raku) in se sme dajati le pod nadzorom zdravnika, usposobljenega za uporabo kemoterapije.
English: Why has Docefrez been approved?
Slovenian: Zakaj je bilo zdravilo Docefrez odobreno?
English: It can also be used with cisplatin (another anticancer medicine) in patients who have not yet received any treatment for their cancer;
Slovenian: Uporablja se lahko tudi s cisplatinom (drugim zdravilom proti raku) pri bolnikih, ki se še niso zdravili;
English: Docefrez is used with cisplatin and 5-fluorouracil (other anticancer medicines);
Slovenian: Zdravilo Docefrez se uporablja v kombinaciji s cisplatinom in 5-fluorouracilom (drugima zdraviloma proti raku);
English: The active substance in Docefrez, docetaxel, belongs to the group of anticancer medicines known as the taxanes.
Slovenian: Zdravilna učinkovina zdravila Docefrez, docetaksel, spada v skupino zdravil za zdravljenje raka, ki jim pravimo taksani.
English: Because Docefrez is a generic medicine, its benefit and risk are taken as being the same as the
Slovenian: Ker je Docefrez generično zdravilo, so koristi in tveganja, povezani z njim, enaki kot pri referenčnem zdravilu.
English: Docefrez is used with prednisone or prednisolone (anti-inflammatory medicines);
Slovenian: Zdravilo Docefrez se uporablja s prednizonom ali prednizolonom (protivnetnimi zdravili);
English: Docefrez is a powder and solvent that is made up to a solution for infusion (drip into a vein).
Slovenian: Zdravilo Docefrez sestavljata prašek in vehikel za pripravo raztopine za infundiranje (kapalne infuzije v veno).
English: The full EPAR for Docefrez can be found here.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Docefrez je na voljo tukaj.
English: What is Docefrez used for?
Slovenian: Za kaj se zdravilo Docefrez uporablja?
English: How has Docefrez been studied?
Slovenian: Kako je bilo zdravilo Docefrez raziskano?
English: No additional studies in patients were needed as Docefrez is given by infusion and contains the same active substance as the reference medicine, Taxotere.
Slovenian: Ker se zdravilo Docefrez daje z infundiranjem in vsebuje enako zdravilno učinkovino kot referenčno zdravilo Taxotere, dodatne študije pri bolnikih niso potrebne.
English: What is Docefrez?
Slovenian: Kaj je zdravilo Docefrez?
English: How is Docefrez used?
Slovenian: Kako se zdravilo Docefrez uporablja?
English: How does Docefrez work?
Slovenian: Kako zdravilo Docefrez deluje?
English: Submission of final study report.
Slovenian: Predati končno poročilo študije.
English: Date of first authorisation: 07 November 2001 Date of latest renewal: 07 November 2006
Slovenian: Datum prve odobritve: 7. november 2001 Datum zadnjega podaljšanja: 7. november 2006
English: 12 months 24 months 36 months 48 months 60 months Survival 36 months 48 months 60 months
Slovenian: 12 mesecev 24 mesecev 36 mesecev 48 mesecev 60 mesecev preživetje 36 mesecev 48 mesecev 60 mesecev
English: Best response
Slovenian: najboljši odziv
English: • Do not use this medicine after the expiry date which is stated on the carton after EXP.
Slovenian: • Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli poleg oznake EXP.
English: The Kaplan-Meier estimate for survival after 36-month follow-up is 68%.
Slovenian: Kaplan-Meierjeva ocena za preživetje po 36-mesečnem spremljanju je 68 %.
English: Do not take Glivec: - if you are allergic to imatinib or any of the other ingredients of this medicine (listed in section 6).
Slovenian: Ne jemljite zdravila Glivec - če ste alergični na imatinib ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Older people: Imatinib pharmacokinetics have not been specifically studied in older people.
Slovenian: Starejši ljudje: Farmakokinetike imatiniba pri starejših ljudeh niso posebej proučili.
English: They contain a white to yellow powder.
Slovenian: Vsebujejo bel do rumen prašek.
English: Longer duration of the treatment (> 36 months) may delay the onset of further recurrences; however the impact of this finding on the overall survival remains unknown.
Slovenian: Daljše trajanje zdravljenja (> 36 mesecev) bi lahko podaljšalo čas do nadaljnjih ponovitev bolezni, vendar vpliv tega pojava na celotno preživetje še vedno ni znan.
English: Results are provided in Table 6.
Slovenian: Rezultati so prikazani v preglednici 6.
English: They have “glivec” on one side.
Slovenian: Na eni strani imajo oznako “glivec”.
English: In all clinical studies 38-40% of patients were  60 years of age and 10-12% of patients were  70 years of age.
Slovenian: V vseh kliničnih študijah je bilo 38-40 % bolnikov starih  60 let, 10-12 % bolnikov pa je bilo starih  70 let.
English: Table 6 Best tumour response in trial STIB2222 (GIST)
Slovenian: Preglednica 6 Najboljši tumorski odziv v preskušanju STIB2222 (GIST)
English: The amount of Glivec given will depend on your child's condition, body weight and height.
Slovenian: Potrebna količina zdravila Glivec bo odvisna od otrokovega stanja, telesne mase in višine.
English: When and how to take Glivec - Take Glivec with a meal.
Slovenian: Kdaj in kako jemati zdravilo Glivec - Zdravilo Glivec vzemite z obrokom hrane.
English: Accelerated phase: 235 adult patients with accelerated phase disease were enrolled.
Slovenian: Pospešena faza: Vključili so 235 odraslih bolnikov s pospešeno fazo bolezni.
English: %(CI)
Slovenian: %(IZ)