FrancophonIA/ELRC3.0 huggingface dataset:
English: The pharmacokinetics of Varuby was not studied in patients with severe hepatic impairment (Child-Pugh Class C).
Croatian: Farmakokinetika lijeka Varuby nije ispitivana u bolesnika s teškim oštećenjem funkcije jetre
English: Arthralgia Back pain Muscular weakness Rhabdomyolysis
Croatian: Poremećaji uha i labirinta hipoakuzija tinitus
English: Respiratory, thoracic and mediastinal disorders
Croatian: Poremećaji dišnog sustava, prsišta i sredoprsja štucanje dispneja
English: Varuby 90 mg film-coated tablets Rolapitant
Croatian: Varuby 90 mg filmom obložene tablete rolapitant
English: The systemic exposures (Cmax and AUC) to rolapitant increased in a dose-proportional manner when the dose of rolapitant increased from 4.5 mg to 180 mg. With an increase in dose by 4 times from the recommended clinical dose of 180 mg, the Cmax and AUC of rolapitant increased by 3.1 fold and 3.7 fold, respectively.
Croatian: Sistemska izloženost (Cmax i AUC) rolapitantu porasla je proporcionalno dozi kada je doza rolapitanta povećana s 4,5 mg na 180 mg.
English: Varuby 90 mg film-coated tablets
Croatian: Varuby 90 mg filmom obložene tablete
English: Rolapitant, the active substance in Varuby, blocks substance P from attaching to these nerve cells and this helps prevent nausea and vomiting.
Croatian: P na te živčane stanice, a to pomaže u sprječavanju mučnine i povraćanja.
English: These include: - propafenone (used to treat irregular or abnormal heart beat) - tamoxifen (used to treat breast cancer) - metoprolol (used to treat high blood pressure and heart conditions) - thioridazine (used to treat psychiatric conditions like schizophrenia) - pimozide (used to treat psychiatric conditions like schizophrenia) - morphine (used to treat moderate to severe pain) - methotrexate (used to treat cancer, psoriasis, and rheumatoid arthritis) - irinotecan (used to treat cancer) - topotecan (used to treat cancer) - mitoxantrone (used to treat cancer) - sulfasalazine (used to treat bowel disease and rheumatoid arthritis) - doxorubicin (used in cancer chemotherapy) - bendamustine (used in the treatment of leukaemia) - digoxin (used to treat heart conditions) - dabigatran (used to prevent blood clots) - colchicine (used to treat gout) - medicines called ‘statins,' such as atorvastatin, fluvastatin, rosuvastatin and simvastatin, that are used in the treatment of high levels of fats (such as cholesterol) in the blood - bosentan (used to treat high blood pressure in the pulmonary artery) - fexofenadine (used to treat allergy symptoms)
Croatian: - tioridazin (koristi se za liječenje psihijatrijskih bolesti kao što je shizofrenija) - pimozid (koristi se za liječenje psihijatrijskih bolesti kao što je shizofrenija) - morfin (koristi se za liječenje umjerenih do teških bolova) - metotreksat (koristi se za liječenje raka, psorijaze i reumatoidnog artritisa) - irinotekan (koristi se za liječenje raka) - topotekan (koristi se za liječenje raka)
English: Chemotherapy can cause the body to release “substance P.” Substance P attaches to nerve cells in the brain's vomiting centre and makes you feel sick or be sick.
Croatian: Tvar P se veže na živčane stanice u centru za povraćanje u mozgu te tako uzrokuje mučninu i povraćanje.
English: Constipation Diarrhoea Dyspepsia
Croatian: Krvožilni poremećaji hipertenzija
English: Control (N=262)
Croatian: Kontrola (N = 262) Udio (%)
English: International Normalised Ratio increased Leukopenia
Croatian: Poremećaji krvi i limfnog sustava neutropenija povećan međunarodni normalizirani omjer leukopenija smanjen broj neutrofila trombocitopenija
English: - you have severe liver or kidney problems - you need to take certain medicines which may reduce the effectiveness of Varuby, such as: - rifampicin, to treat tuberculosis and other infections - carbamazepine, to treat epilepsy and nerve pain - phenobarbital, to treat epilepsy - enzalutamide, to treat prostate cancer - phenytoin, to treat epilepsy - efavirenz, to treat human immunodeficiency virus (HIV) - rifabutin, to treat tuberculosis and other infections - other medicines that contain an NK1 antagonist, such as aprepitant and a combination of netupitant and palonosetron hydrochloride (for the prevention of nausea and vomiting associated with cancer chemotherapy) (see section 2 under ‘Other medicines and Varuby')
Croatian: rifabutin za liječenje tuberkuloze i drugih infekcija drugi lijekovi koji sadrže antagonist NK1 receptora kao što su aprepitant i kombinacija netupitanta i palonosetronklorida (za sprječavanje mučnine i povraćanja povezanih s kemoterapijom raka) (pogledajte dio 2 pod „Drugi lijekovi i Varuby“)
English: Overall a Unadjusted P-values are obtained from Cochran-Mantel-Haenszel test. N.S.=Not significant (p>0.05) The estimated time to first emesis or use of rescue medicinal product in patients receiving a MEC regimen is depicted by the Kaplan-Meier plot in Figure 2.
Croatian: Procijenjeno vrijeme do prvog povraćanja ili primjene lijeka za hitno ublažavanje simptoma u bolesnika koji su primali režim MEC prikazano je Kaplan-Meierovom krivuljom na Slici 2.
English: Ondansetron
Croatian: Ondanzetron
English: A total of 2,798 subjects received oral rolapitant at any dose, including 1,567 subjects in the CINV (chemotherapy-induced nausea and vomiting) studies.
Croatian: Ukupno je 2798 ispitanika primilo rolapitant peroralno u bilo kojoj dozi,
English: Cisplatin-Based Highly Emetogenic Chemotherapy (HEC)
Croatian: Highly Emetogenic Chemotherapy, HEC) i umjereno emetogene kemoterapije (engl.
English: Balance disorder Movement disorder Syncope
Croatian: Poremećaji živčanog sustava glavobolja omaglica poremećaj pažnje disgeuzija somnolencija poremećaj ravnoteže poremećaj pokreta sinkopa
English: In a three-month rat study, clonic convulsions were observed in a single animal at 125 mg/kg/day (approximately 6 times the recommended human dose on a body surface area basis).
Croatian: 125 mg/kg/dan (približno 6 puta preporučene doze za ljude na temelju tjelesne površine).
English: - feeling dizzy, difficulty concentrating, lack of energy, feeling sleepy (somnolence) or trouble sleeping (insomnia) - stomach problems including stomach discomfort, bloating, nausea, pain, indigestion, and diarrhoea - low levels of white blood cells which fight infections (shown in blood tests) - infection in the mouth - mouth sores - decreased appetite - hiccups - weakness
Croatian: • problemi u trbuhu uključujući nelagodu, nadutost, mučninu, bol, probavne tegobe i proljev
English: Other CYPs
Croatian: Drugi enzimi CYP
English: How to store Varuby
Croatian: Kako čuvati Varuby
English: Dizziness Disturbance in attention Dysgeusia Somnolence
Croatian: Psihijatrijski poremećaji nesanica anksioznost bruksizam
English: Efficacy Endpointsa
Croatian: Mjere ishoda djelotvornostia
English: No Emesis
Croatian: I DOHVATA
English: Hiccups
Croatian: • štucanje
English: P-Valueb
Croatian: P-vrijedno stb
English: A 70% increase in Cmax and 30% increase in AUC of digoxin, a P-gp substrate, were observed when administered with a single dose of 180 mg rolapitant.
Croatian: Kada se digoksin, supstrat P-gp-a, primijeni zajedno s jednokratnom dozom od 180 mg rolapitanta, zabilježen je porast Cmax digoksina za 70 % i porast AUC
English: You may feel dizzy or tired after taking this medicine.
Croatian: Nakon uzimanja lijeka možete osjećati omaglicu ili umor.
English: The following adverse reactions were observed in a pooled analysis of the Highly Emetogenic Chemotherapy (HEC) and Moderately Emetogenic Chemotherapy (MEC) studies.
Croatian: Objedinjenom analizom ispitivanja jako emetogene kemoterapije (engl.
English: N=322
Croatian: Druga kemoterapija N = 322
English: Infections and infestations
Croatian: • infekcija u ustima
English: B. PACKAGE LEAFLET
Croatian: • zamagljen vid
English: Tablet content
Croatian: PRIMJENU LIJEKA
English: Abdominal discomfort Change of bowel habit Dry mouth
Croatian: • promjene u radu debelog crijeva
English: Heart rate increased
Croatian: Doziranje Odrasli
English: - Main inclusion criteria:
Croatian: - Glavni kriteriji za uključivanje:
English: Comparison based on historic control.
Croatian: Usporedba na temelju povijesnih kontrola.
English: V179F was never present without Y181C.
Croatian: V179F nikada nije bio prisutan bez Y181C.
English: Amiodarone Bepridil
Croatian: Amiodaron Bepridil
English: A limited number of females were included in the studies.
Croatian: U ispitivanja je bio uključen ograničeni broj žena.
English: Talk to your doctor first.
Croatian: Najprije razgovarajte sa svojim liječnikom.
English: N = number of subjects with data; n = number of observations.
Croatian: N = broj ispitanika s podacima; n = broj opservacija.
English: What INTELENCE is and what it is used for
Croatian: Što je INTELENCE i za što se koristi
English: n = 9 for AUC12h
Croatian: n = 9 za AUC12h
English: Use in adults Other form(s) of this medicine may be more suitable for adults.
Croatian: Primjena u odraslih Drugi oblik(ci) ovog lijeka može biti prikladniji za odrasle.
English: Combining two NNRTIs has not been shown to be beneficial.
Croatian: Kombiniranje dva NNRTI nije se pokazalo korisnim.
English: The clinical relevance of this interaction has not been demonstrated.
Croatian: Nije dokazana klinička važnost ove interakcije.
English: Treatment difference (95% CI)
Croatian: Razlika liječenja (95% CI)
English: Your doctor will discuss with you which combination of medicines is best for you.
Croatian: Vaš će liječnik zajedno s Vama razmotriti koja je kombinacija lijekova za Vas najbolja.
English: Other medicines and INTELENCE
Croatian: Drugi lijekovi i INTELENCE
English: This difference between treatment arms was statistically significant.
Croatian: Ova razlika između liječenih skupina bila je statistički značajna.
English: Your doctor will explain these to you.
Croatian: Vaš liječnik će Vam to objasniti.
English: The clinical data do not raise safety concern but are very limited.
Croatian: Klinički podaci ne ukazuju na pitanja sigurnosti, ali su vrlo ograničeni.
English: Typically, such reactions have been observed within the first weeks or months of initiation of CART.
Croatian: Uobičajeno, takve su reakcije opažene u prvih nekoliko tjedana ili mjeseci po uvođenju KART-a.
English: The use of warm (> 40°C) or carbonated beverages should be avoided.
Croatian: Mora se izbjegavati primjena vrućih (> 40°C) ili gaziranih pića.
English: If you take INTELENCE on an empty stomach, only half the amount of INTELENCE is absorbed.
Croatian: Ako uzmete INTELENCE na prazan želudac, apsorbira se samo pola količine lijeka INTELENCE.
English: Tell your doctor immediately if you are pregnant.
Croatian: Odmah obavijestite svoga liječnika ako ste trudni.
English: • on a stable antiretroviral regimen for at least 8 weeks.
Croatian: • na stabilnom liječenju antiretrovirusnim lijekovima najmanje 8 tjedana.
English: These individual mutations occurred in the presence of other NNRTI RAMs.
Croatian: Te pojedinačne mutacije javljale su se u prisutnosti drugih NNRTI RAMova.
English: It is part of a treatment reducing the amount of virus in the blood.
Croatian: On je dio liječenja kojim se smanjuje količina virusa u krvi.
English: In rare instances, very serious rash has been reported which can be potentially life-threatening.
Croatian: U vrlo rijetkim slučajevima prijavljen je vrlo ozbiljan osip koji potencijalno može biti opasan po život.
English: The terminal elimination half-life of etravirine was approximately 30-40 hours.
Croatian: Terminalni poluvijek etravirina bio je približno 30-40 sati.
English: Pregnant women should not take INTELENCE unless specifically directed by the doctor.
Croatian: Trudnice ne smiju uzimati INTELENCE osim ukoliko im to liječnik posebno ne odredi.
English: ≥ 50 and < 200 ≥ 200 and < 350
Croatian: ≥ 50 i < 200 ≥ 200 i < 350
English: Any AIDS defining illness and/or death n (%)
Croatian: Bilo koja bolest koja definira AIDS i/ili smrt, n (%)
English: Mean ± SD (median)
Croatian: SD (medijan)
English: Warnings and precautions Talk to your doctor or pharmacist before taking INTELENCE.
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku ili ljekarniku prije nego uzmete INTELENCE.
English: The pharmacokinetics in other races have not been sufficiently evaluated.
Croatian: Farmakokinetika u drugih rasa nije dovoljno procijenjena.
English: Alternatives to diazepam should be considered.
Croatian: Treba razmotriti alternative diazepamu.
English: The doctor will inform you exactly how much INTELENCE the child should take.
Croatian: Liječnik će Vam objasniti koliko točno lijeka INTELENCE dijete mora uzeti.
English: * based on population pharmacokinetic analyses
Croatian: * na temelju populacijskih farmakokinetičkih analiza
English: These pouches should stay in the bottle all the time and are not to be eaten.
Croatian: Te vrećice sa sredstvom za sušenje trebaju cijelo vrijeme ostati u boci i ne smiju se pojesti.
English: Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
Croatian: Obavijestite svog liječnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: - Tell your doctor immediately if you notice any symptoms of infections.
Croatian: - Odmah recite svom liječniku ako primjetite bilo kakve simptome infekcije.
English: The tablet can be divided into two equal doses.
Croatian: Tableta se može razdijeliti na dvije jednake doze.
English: INTELENCE must always be given in combination with other antiretroviral medicinal products.
Croatian: INTELENCE se uvijek mora davati u kombinaciji s drugim antiretrovirusnim lijekovima.
English: Date of first authorisation: 28 August 2008 Date of latest renewal: 23 August 2018
Croatian: Datum posljednje obnove odobrenja: 23. kolovoza 2018.
English: In other cases, increased monitoring and/or a change in the dose of the medicine may be needed.
Croatian: U drugim slučajevima može biti potrebno pozorno praćenje i/ili promjena doze lijeka.
English: If you forget to take INTELENCE
Croatian: Ako ste zaboravili uzeti INTELENCE
English: Driving and using machines Do not drive or operate machines if you feel sleepy or dizzy after taking your medicines.
Croatian: Nemojte voziti niti rukovati strojevima ako osjećate pospanost ili omaglicu nakon uzimanja lijekova.
English: INTELENCE has only been used in a limited number of patients of 65 years or older.
Croatian: INTELENCE je primjenjivan samo kod ograničenog broja bolesnika u dobi od 65 godina ili starijih.
English: What INTELENCE is and what it is used for What you need to know before you take INTELENCE How to take INTELENCE
Croatian: Što je INTELENCE i za što se koristi Što morate znati prije nego počnete uzimati INTELENCE Kako uzimati INTELENCE
English: Follow your doctor's advice on the type of meal you should be taking with INTELENCE.
Croatian: Slijedite savjet liječnika o vrsti obroka koji morate uzeti uz INTELENCE.
English: Autoimmune disorders may occur many months after the start of treatment.
Croatian: Autoimuni poremećaji mogu se javiti mnogo mjeseci nakon početka liječenja.
English: Do not give this medicine to children less than 6 years of age and weighing less than 16 kg because the potential benefits and risks have not yet been established.
Croatian: Nemojte davati ovaj lijek djeci u dobi manjoj od 6 godina i težine manje od 16 kg jer nisu još ustanovljene moguće koristi i rizici primjene.
English: Even if you feel better, do not stop taking INTELENCE or your other anti-HIV medicines.
Croatian: Čak i ako se osjećate bolje, nemojte prestati uzimati INTELENCE ili druge lijekove protiv HIV-a.
English: Tell your doctor about your situation
Croatian: Objasnite liječniku svoje stanje
English: However, some combinations are not recommended.
Croatian: Međutim, neke kombinacije se ne preporučuju.
English: With an associated boosted PI:
Croatian: S udruženim pojačanim IP:
English: Lopinavir/ritonavir (tablet)
Croatian: Lopinavir/ritonavir (tableta)
English: H2-RECEPTOR ANTAGONISTS Ranitidine
Croatian: ANTAGONISTI H2-RECEPTORA Ranitidin
English: Enfuvirtide concentrations not studied and no effect is expected.
Croatian: Koncentracije enfuvirtida nisu ispitivane i ne očekuje se učinak.
English: What you need to know before you take INTELENCE
Croatian: Što morate znati prije nego počnete uzimati INTELENCE
English: Table 1:
Croatian: TABLICA 1:
English: It is believed that these symptoms are due to an improvement in the body's immune response, enabling the body to fight infections that may have been present with no obvious symptoms.
Croatian: Vjeruje se da ti simptomi nastaju zbog poboljšanja imunosnog odgovora organizma koji tijelu omogućuje borbu protiv infekcija koje su možda bile prisutne bez vidljivih simptoma.
English: The effects of INTELENCE or other medicines might be influenced if you take INTELENCE together with any of the following medicines.
Croatian: Može doći do utjecaja na učinak lijeka INTELENCE ili drugih lijekova ako uzimate INTELENCE zajedno s bilo kojim od sljedećih lijekova.
English: Frequencies are defined as very common (≥ 1/10), common (≥ 1/100 to < 1/10) and uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000) and very rare (< 1/10,000).
Croatian: Učestalost je definirana kao vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10) i manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10000 i < 1/1000) i vrlo rijetko (< 1/10000).
English: Make sure that you check the following points and tell your doctor if any of these apply to you.
Croatian: Svakako provjerite sljedeće točke i upozorite liječnika ako se bilo koja od njih na odnosi na Vas.
English: Treatment of overdose with INTELENCE consists of general supportive measures including monitoring of vital signs and observation of the clinical status of the patient.
Croatian: Liječenje predoziranja lijekom INTELENCE sastoji se od općih potpornih mjera koje uključuju praćenje vitalnih funkcija i nadzor kliničkog statusa bolesnika.
English: Etravirine is an NNRTI of human immunodeficiency virus type 1 (HIV-1).
Croatian: Etravirin je NNRTI virusa humane imunodeficijencije tipa 1 (HIV-1).
English: Therefore, INTELENCE should be taken following a meal.
Croatian: Stoga se INTELENCE treba uzimati nakon obroka.
English: If you notice any of these symptoms please inform your doctor.
Croatian: Ukoliko primijetite bilo koji od tih simptoma, molimo obavijestite svog liječnika.
English: This will improve your immune system and reduces the risk of developing illnesses linked to HIV infection.
Croatian: Vaš imunološki sustav i smanjiti rizik razvijanja bolesti povezanih s HIV infekcijom.
English: Contact your doctor if you are uncertain about what to do if you miss a dose or vomit.
Croatian: Obratite se svom liječniku ako niste sigurni što napraviti ako ste propustili dozu ili ako povraćate.
English: Known and theoretical interactions with selected antiretrovirals and non-antiretroviral medicinal products are listed in table 1.
Croatian: Poznate i teoretski moguće interakcije s odabranim antiretrovirusnim i ne-antiretrovirusnim lijekovima navedene su u tablici 1.
English: See also section 4.4.
Croatian: Vidjeti dio 4.4.
English: - Do not use warm (40°C and above) or carbonated beverages when taking INTELENCE tablet(s).
Croatian: - nemojte uzimati vruća (40°C i iznad) ili gazirana pića uz INTELENCE tabletu(e).
English: Etravirine was not carcinogenic in rats and in male mice.
Croatian: Etravirin nije bio karcinogen u štakora i u mužjaka miševa.
English: • 3 or more primary PI mutations at screening
Croatian: • 3 ili više primarnih IP mutacija na probiru
English: Therefore, always tell your doctor which other anti-HIV medicines you take.
Croatian: Stoga, uvijek obavijestite svog liječnika o drugim lijekovima protiv HIV-a koje uzimate.
English: If a rash occurs, it usually appears soon after anti-HIV treatment with INTELENCE is started and often disappears within 1 to 2 weeks, even with continued use of the medicine.
Croatian: Ako se pojavi osip, obično se pojavi ubrzo nakon uvođenja anti-HIV liječenja lijekom INTELENCE, a često nestaje unutar 1 do 2 tjedna čak i uz nastavak primjene lijeka.
English: Then take the next dose as usual.
Croatian: Zatim uzmite sljedeću dozu kako je inače propisano.
English: Results of this analysis (week 48 data) by ENF stratum are shown in table 3.
Croatian: Rezultati te analize (podaci u 48.tjednu) prema ENF skupini prikazani su u tablici 3.
English: Do not chew the tablet(s).
Croatian: Tabletu(e) nemojte žvakati.
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Croatian: Ako primijetite bilo koji simptom infekcije ili druge simptome poput mišićne slabosti, slabosti koja počinje u šakama i stopalima te se širi gore prema trupu tijela, lupanja srca, tremora ili hiperaktivnosti, molimo Vas odmah obavijestite liječnika i zatražite potrebno liječenje.
English: Do not take INTELENCE - if you are allergic to etravirine or any of the other ingredients of this medicine (listed in section 6) - if you are taking elbasvir/grazoprevir (a medicine to treat hepatitis C infection).
Croatian: Nemojte uzimati INTELENCE - ako ste alergični na etravirin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.) - ako uzimate elbasvir/grazoprevir (lijek za liječenje hepatitis C infekcije).
English: Studies in animals do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3).
Croatian: Ispitivanja na životinjama ne ukazuju na izravne ili neizravne štetne učinke vezano uz trudnoću, razvoj embrija/fetusa, porođaj ili postnatalni razvoj (vidjeti dio 5.3).
English: Time to onset is usually around 3-6 weeks and the outcome in most cases is favourable upon discontinuation and after initiation of corticosteroid therapy.
Croatian: Vrijeme do pojave je obično 3-6 tjedana i ishod je u većini slučajeva povoljan nakon prestanka uzimanja lijeka i početka terapije kortikosteroidima.
English: Systemic dexamethasone should be used with caution or alternatives should be considered, particularly for chronic use.
Croatian: Sistemski deksametazon treba primjenjivati s oprezom ili treba razmotriti druge mogućnosti, osobito za kroničnu primjenu.
English: Exposure to etravirine was lower (35-50%) in HIV-1 infected patients than in healthy subjects.
Croatian: Izloženost etravirinu bila je manja (35-50%) u bolesnika zaraženih virusom HIV-1 nego u zdravih ispitanika.
English: However, unbound concentrations have not been assessed.
Croatian: Međutim, nevezane koncentracije nisu procijenjene.
English: The recommended dose for maraviroc when combined with INTELENCE and a PI is 150 mg twice daily, except for fosamprenavir/ritonavir which is not recommended with maraviroc.
Croatian: Preporučena doza za maravirok kada se kombinira s lijekom INTELENCE i IP je 150 mg dva puta dnevno osim za fosamprenavir/ritonavir koji nisu preporučeni s maravirokom.
English: The table is not all-inclusive.
Croatian: U tablicu nije sve uključeno.
English: Since there was a significant interaction effect between treatment and ENF, the primary analysis was done for 2 ENF strata (patients reusing or not using ENF versus patients using ENF de novo).
Croatian: Budući da je postojala značajna interakcija između liječenja i ENF, primarna analiza provedena je za 2 ENF sloja (bolesnici koji su ponovo uzimali ili koji nisu uzimali ENF u usporedbi s bolesnicima koji su primjenjivali ENF de novo).
English: Etravirine is approximately 99.9% bound to plasma proteins, primarily to albumin (99.6%) and α1-acid glycoprotein (97.66%-99.02%) in vitro.
Croatian: Etravirin je otprilike 99,9% vezan na proteine plazme, uglavnom na albumin (99,6%) i α1-kiseli glikoprotein (97,66%-99,02%) in vitro.
English: With no associated boosted PI (out of the recommended indication for etravirine): rifabutin
Croatian: Bez udruženih pojačanih IP (izvan preporučene indikacije za etravirin) rifabutin
English: Animal toxicology studies have been conducted with etravirine in mice, rats, rabbits and dogs.
Croatian: Toksikološka ispitivanja s etravirinom na životinjama provedena su na miševima, štakorima, kunićima i psima.