FrancophonIA/ELRC3.0 huggingface dataset:
English: What Votubia dispersible tablets looks like and contents of the pack Votubia 1 mg dispersible tablets are white to slightly yellowish, round, flat tablets with a bevelled edge and no score.
Spanish: Aspecto de Votubia comprimidos dispersables y contenido del envase Votubia 1 mg comprimidos dispersables son comprimidos redondos, planos, blancos a ligeramente amarillentos, con un borde biselado y sin ranura.
English: Otitis media, cellulitis, pharyngitis streptococcal, gastroenteritis viral, gingivitis Uncommon Herpes zoster, sepsis, bronchitis viral Blood and lymphatic system disorders Common
Spanish: Otitis media, celulitis, faringitis estreptocócica, gastroenteritis vírica, gingivitis
English: Votubia 5 mg tablets are white to slightly yellowish, elongated tablets.
Spanish: Votubia 5 mg comprimidos son comprimidos alargados blancos a ligeramente amarillos.
English: Lymphoedema
Spanish: Linfoedema
English: 10 x 1 dispersible tablets 30 x 1 dispersible tablets 100 x 1 dispersible tablets
Spanish: 10 x 1 comprimidos dispersables 30 x 1 comprimidos dispersables 100 x 1 comprimidos dispersables
English: Each Votubia 2.5 mg tablet contains 2.5 mg of everolimus.
Spanish: Cada comprimido de Votubia 2,5 mg contiene 2,5 mg de everolimus.
English: Votubia 5 mg tablets
Spanish: Votubia 5 mg comprimidos
English: If the patient does not drink it within 30 minutes if an oral syringe has been used or within 60 minutes if a small glass has been used, throw it away and prepare a new suspension.
Spanish: Si el paciente no la bebe en 30 minutos, cuando se utiliza jeringa oral, o en 60 minutos, cuando se toma en un vaso pequeño, se debe tirar la suspensión y preparar una nueva.
English: 10 x 1 tablets
Spanish: 10 x 1 comprimidos
English: Votubia 1 mg dispersible tablets are available in packs containing 30 dispersible tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 1 mg comprimidos dispersables está disponible en envases que contienen 30 comprimidos dispersables, en blisters unidosis perforados de 10 x 1 comprimidos cada uno.
English: 30 x 1 tablets
Spanish: 30 x 1 comprimidos
English: Excipient with known effect Each dispersible tablet contains 0.98 mg lactose.
Spanish: Excipiente con efecto conocido Cada comprimido dispersable contiene 0,98 mg de lactosa
English: Cmax is dose-proportional between 5 and 10 mg. tmax occurs at 1 to 2 hours post-dose.
Spanish: La Cmax es proporcional a la dosis entre 5 y 10 mg.
English: Metabolism and nutrition disorders Very common Decreased appetite, hypercholesterolaemia Common
Spanish: Disminución del apetito, hipercolesterolemia
English: AUC ↑3.5-fold (range 2.2-6.3) Cmax ↑2.3-fold (range1.3-3.8)
Spanish: AUC ↑3,5 veces (intervalo 2,2-6,3) Cmax ↑2,3 veces (intervalo 1,3-3,8)
English: Being sick (vomiting)
Spanish: Sensación de mareo (vómitos)
English: Dyslipidaemia (including hypercholesterolaemia and hypertriglyceridaemia) has been reported in patients taking Votubia.
Spanish: En pacientes tratados con Votubia se ha notificado dislipemia (incluyendo hipercolesterolemia e hipertrigliceridemia).
English: Each tablet contains 2.5 mg everolimus.
Spanish: Cada comprimido contiene 2,5 mg de everolimus.
English: Packs containing 10 x 1, 30 x 1 or 100 x 1 tablets.
Spanish: Envases que contienen 10 x 1, 30 x 1 o 100 x 1 comprimidos.
English: Each Votubia 10 mg tablet contains 10 mg of everolimus.
Spanish: Cada comprimido de Votubia 10 mg contiene 10 mg de everolimus.
English: 30 x 1 dispersible tablets 100 x 1 dispersible tablets
Spanish: 30 x 1 comprimidos dispersables 100 x 1 comprimidos dispersables
English: Packs containing 30 x 1 or 100 x 1 dispersible tablets
Spanish: Envases que contienen 30 x 1 o 100 x 1 comprimidos dispersables
English: A higher starting dose of 7 mg/m is therefore recommended for patients 1 to less than 3 years of age with SEGA (see section 4.2).
Spanish: Se recomienda una dosis de inicio más alta, 7 mg/m2, en pacientes de 1 año a menos de
English: Votubia 10 mg tablets everolimus
Spanish: Votubia 10 mg comprimidos everolimus
English: Renal angiomyolipoma associated with tuberous sclerosis complex (TSC)
Spanish: Angiomiolipoma renal asociado con el complejo esclerosis tuberosa (CET)
English: Votubia may be reinitiated at a daily dose approximately 50% lower than the dose previously administered.
Spanish: Puede reiniciarse el tratamiento con Votubia a una dosis diaria aproximadamente un 50% más baja que la dosis administrada previamente.
English: Each tablet contains 10 mg everolimus.
Spanish: Cada comprimido contiene 10 mg de everolimus.
English: 100 x 1 dispersible tablets
Spanish: 100 x 1 comprimidos dispersables
English: Excipient with known effect Each dispersible tablet contains 2.94 mg lactose.
Spanish: Excipiente con efecto conocido: Cada comprimido dispersable contiene 2,94 mg de lactosa.
English: 10 x 1 dispersible tablets
Spanish: 10 x 1 comprimidos dispersables
English: They are engraved with “UHE” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «UHE» en una cara y «NVR» en la otra.
English: Excipient with known effect Each dispersible tablet contains 4.90 mg lactose.
Spanish: Excipiente con efecto conocido: Cada comprimido dispersable contiene 4,90 mg de lactosa.
English: Packs containing 10 x 1, 30 x 1 or 100 x 1 dispersible tablets.
Spanish: Envases que contienen 10 x 1, 30 x 1 o 100 x 1 comprimidos dispersables.
English: 30 x 1 dispersible tablets
Spanish: 30 x 1 comprimidos dispersables
English: Common side effects (may affect up to 1 in 10 people) Swelling, feeling of heaviness or tightness, pain, limited mobility of body parts (this could occur anywhere in the body and is a potential sign of an abnormal build-up of fluid in soft tissue due to a blockage in the lymphatic system, also known as lymphoedema) Rash, itching, hives, difficulty breathing or swallowing, dizziness (signs of serious allergic reaction, also known as hypersensitivity) Fever, cough, difficulty breathing, wheezing (signs of inflammation of the lung, also known as pneumonitis)
Spanish: Efectos adversos frecuentes (pueden afectar hasta 1 de cada 10 personas) Hinchazón, sensación de pesadez o tensión, dolor, movilidad limitada de partes del cuerpo (esto puede aparecer en cualquier parte del cuerpo y es un signo potencial de un aumento anormal de líquido en el tejido blando debido a un bloqueo del sistema linfático, también conocido como linfoedema)
English: Votubia 1 mg dispersible tablets
Spanish: Votubia 1 mg comprimidos dispersables
English: Missing
Spanish: Desconocido
English: Each Votubia 3 mg dispersible tablet contains 3 mg of everolimus.
Spanish: Cada comprimido dispersable de Votubia 3 mg contiene 3 mg de everolimus.
English: Votubia 5 mg tablets everolimus
Spanish: Votubia 5 mg comprimidos everolimus
English: They are engraved with “5” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «5» en una cara y «NVR» en la otra.
English: Each Votubia 5 mg tablet contains 5 mg of everolimus.
Spanish: Cada comprimido de Votubia 5 mg contiene 5 mg de everolimus.
English: White to slightly yellow, elongated tablets of approximately 10.1 x 4.1 mm, with a bevelled edge and no score, engraved with “LCL” on one side and “NVR” on the other.
Spanish: Comprimidos alargados, blancos a ligeramente amarillos, de aproximadamente 10,1 x 4,1 mm, con un borde biselado y sin ranura, con la inscripción «LCL» en una cara y «NVR» en la otra.
English: After preparation the suspension must be taken straight away.
Spanish: Se debe utilizar la suspensión inmediatamente después de la preparación.
English: Votubia 3 mg and Votubia 5 mg dispersible tablets are available in packs containing 30 x 1 or 100 x1 dispersible tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 3 mg y 5 mg comprimidos dispersables está disponible en envases que contienen 30 x 1 o 100 x 1 comprimidos dispersables, en blísters unidosis perforados de 10 x 1 comprimidos cada uno.
English: higher starting dose of 7 mg/m is recommended for patients 1 to less than 3 years of age based on pharmacokinetic simulations (see section 5.2).
Spanish: 3 años de edad de acuerdo a las simulaciones farmacocinéticas (ver sección 5.2).
English: Epistaxis, pneumonitis Gastrointestinal disorders Very common Stomatitis b, diarrhoea, vomiting
Spanish: Estomatitis b, diarrea, vómitos
English: Votubia 5 mg dispersible tablets
Spanish: Votubia 5 mg comprimidos dispersables
English: Each tablet contains 5 mg everolimus.
Spanish: Cada comprimido contiene 5 mg de everolimus.
English: Patients initially treated with placebo were allowed to cross over to everolimus at the time of angiomyolipoma progression and upon recognition that treatment with everolimus was superior to treatment with placebo.
Spanish: Sobre el reconocimiento de que el tratamiento con everolimus fue superior al tratamiento con placebo, los pacientes tratados inicialmente con placebo se les permitió cambiar a everolimus en el momento de la progresión del angiomiolipoma.
English: Votubia 1 mg dispersible tablets everolimus
Spanish: Votubia 1 mg comprimidos dispersables everolimus
English: Each dispersible tablet contains 1 mg everolimus.
Spanish: Cada comprimido dispersable contiene 1 mg de everolimus.
English: Packs containing 30 x 1 or 100 x 1 tablets.
Spanish: Envases que contienen 30 x 1 o 100 x 1comprimidos.
English: Votubia 5 mg dispersible tablets are white to slightly yellowish, round, flat tablets with a bevelled edge and no score.
Spanish: Votubia 5 mg comprimidos dispersables son comprimidos redondos, planos, blancos a ligeramente amarillentos, con un borde biselado y sin ranura.
English: Votubia 3 mg dispersible tablets
Spanish: Votubia 3 mg comprimidos dispersables
English: Votubia 2 mg dispersible tablets
Spanish: Votubia 2 mg comprimidos dispersables
English: If you do not drink it within 30 minutes when using an oral syringe or within 60 minutes when using a small glass, throw it away and prepare a new suspension.
Spanish: Si no la bebe después de 30 minutos, cuando se ha preparado en una jeringa oral, o bien después de 60 minutos, si se ha utilizado un vaso pequeño, se debe tirar y preparar una nueva suspensión.
English: Each dispersible tablet contains 2 mg everolimus.
Spanish: Cada comprimido dispersable contiene 2 mg de everolimus.
English: Votubia 2 mg dispersible tablets are white to slightly yellowish, round, flat tablets with a bevelled edge and no score.
Spanish: Votubia 2 mg comprimidos dispersables son comprimidos redondos, planos, blancos a ligeramente amarillentos, con un borde biselado y sin ranura.
English: White to slightly yellow, elongated tablets of approximately 15.1 x 6.0 mm, with a bevelled edge and no score, engraved with “UHE” on one side and “NVR” on the other.
Spanish: Comprimidos alargados, blancos a ligeramente amarillos, de aproximadamente 15,1 x 6,0 mm, con un borde biselado y sin ranura, con la marca «UHE» en una cara y «NVR» en la otra.
English: Votubia 3 mg dispersible tablets are white to slightly yellowish, round, flat tablets with a bevelled edge and no score.
Spanish: Votubia 3 mg comprimidos dispersables son comprimidos redondos, planos, blancos a ligeramente amarillentos, con un borde biselado y sin ranura.
English: Constipation, nausea, abdominal pain, flatulence, oral pain, gastritis
Spanish: Sequedad de la piel, dermatitis acneiforme, prurito, alopecia
English: Votubia 3 mg dispersible tablets everolimus
Spanish: Votubia 3 mg comprimidos dispersables everolimus
English: Each dispersible tablet contains 3 mg everolimus.
Spanish: Cada comprimido dispersable contiene 3 mg de everolimus.
English: Votubia 5 mg tablets are available in packs containing 30 x 1 or 100 x 1 tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 5 mg comprimidos está disponible en envases que contienen 30 x 1 o 100 x 1 comprimidos en blísters unidosis perforados de 10 x 1 comprimidos cada uno.
English: White to slightly yellow, elongated tablets of approximately 12.1 x 4.9 mm, with a bevelled edge and no score, engraved with “5” on one side and “NVR” on the other.
Spanish: Comprimidos alargados, blancos a ligeramente amarillos, de aproximadamente 12,1 x 4,9 mm, con un borde biselado y sin ranura, con la marca «5» en una cara y «NVR» en la otra.
English: Votubia 5 mg dispersible tablets everolimus
Spanish: Votubia 5 mg comprimidos dispersables everolimus
English: Votubia 2 mg dispersible tablets everolimus
Spanish: Votubia 2 mg comprimidos dispersables everolimus
English: Votubia 5 mg dispersible tablets, abbreviated form accepted, if required for technical reasons
Spanish: Votubia 5 mg comprimidos dispersables, forma abreviada [comp.disp.]
English: Votubia 1 mg dispersible tablets, abbreviated form accepted, if required for technical reasons
Spanish: Votubia 1 mg comprimidos dispersables, forma abreviada [comp.disp.]
English: Re-initiate Votubia at approximately 50% lower than the daily dose previously administered.
Spanish: Reiniciar el tratamiento con Votubia con una dosis aproximadamente 50% más baja que la dosis diaria administrada previamente.
English: Consider re-initiating Votubia at approximately 50% lower than the daily dose previously administered.
Spanish: Considerar el reinicio del tratamiento con Votubia con una dosis aproximadamente un 50% más baja que la dosis diaria administrada previamente.
English: Each Votubia 5 mg dispersible tablet contains 5 mg of everolimus.
Spanish: Cada comprimido dispersable de Votubia 5 mg contiene 5 mg de everolimus.
English: They are engraved with “D5” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «D5» en una cara y «NVR» en la otra.
English: Votubia 2 mg dispersible tablets are available in packs containing 10 x 1, 30 x 1 or 100 x 1 dispersible tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 2 mg comprimidos dispersables está disponible en envases que contienen 10 x 1, 30 x 1 o 100 x 1 comprimidos dispersables, en blísters unidosis perforados de 10 x 1 comprimidos cada uno.
English: Votubia 10 mg tablets are available in packs containing 10 x 1, 30 x 1 or 100 x 1 tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 10 mg está disponible en envases que contienen 10 x 1, 30 x 1 o 100 x 1 comprimidos en blisters unidosis perforados de 10 x 1 comprimidos cada uno.
English: Votubia 2 mg dispersible tablets, abbreviated form accepted, if required for technical reasons
Spanish: Votubia 2 mg comprimidos dispersables, forma abreviada [comp.disp.]
English: Votubia 2.5 mg tablets are available in packs containing 10 x 1, 30 x 1 or 100 x 1 tablets in perforated unit-dose blisters of 10 x 1 tablets each.
Spanish: Votubia 2,5 mg comprimidos está disponible en envases que contienen 10 x 1, 30 x 1 o 100 x 1 comprimidos en blísters unidosis perforados de 10 x 1 comprimidos cada uno.
English: Votubia 3 mg dispersible tablets, abbreviated form accepted, if required for technical reasons
Spanish: Votubia 3 mg comprimidos dispersables, forma abreviada [comp.disp.]
English: Each dispersible tablet contains 5 mg everolimus.
Spanish: Cada comprimido dispersable contiene 5 mg de everolimus.
English: General disorders and administration site conditions Very common Pyrexia, fatigue Investigations
Spanish: Trastornos generales y alteraciones en el lugar de administración Muy frecuentes
English: If you do not use it within 60 minutes, throw it away and prepare a new suspension.
Spanish: Si no se utiliza durante 60 minutos, se debe desechar y se debe preparar una nueva suspensión.
English: They are engraved with “D3” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «D3» en una cara y «NVR» en la otra.
English: Response rates were 34.6% (95% CI: 24.2, 46.2) for the Votubia arm compared with 0% (95% CI: 0.0, 9.0) for the placebo arm (Table 6).
Spanish: Las tasas de respuesta fueron 34,6% (IC 95%: 24,2, 46,2) para el brazo de Votubia comparado con 0% (IC 95%: 0,0, 9,0) para el brazo de placebo (Tabla 6) Además, los 8 pacientes en el brazo de Votubia que presentaban evidencia radiográfica de hidrocefalia a nivel basal presentaron un descenso en el volumen ventricular.
English: They are engraved with “D1” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «D1» en una cara y «NVR» en la otra.
English: They are engraved with “D2” on one side and “NVR” on the other.
Spanish: Tienen la inscripción «D2» en una cara y «NVR» en la otra.
English: Each Votubia 1 mg dispersible tablet contains 1 mg of everolimus.
Spanish: Cada comprimido dispersable de Votubia 1 mg contiene 1 mg de everolimus Cada comprimido dispersable de Votubia 2 mg contiene 2 mg de everolimus.
English: Wound healing complications
Spanish: Complicaciones en la cicatrización de heridas
English: White to slightly yellowish, round, flat tablets of approximately 12.1 mm in diameter, with a bevelled edge and no score, engraved with “D5” on one side and “NVR” on the other.
Spanish: Comprimidos redondos, planos, blancos a ligeramente amarillentos, de aproximadamente 12,1 mm de diámetro, con un borde biselado y sin ranura, con la inscripción «D5» en una cara y «NVR» en la otra.
English: White to slightly yellowish, round, flat tablets of approximately 7.1 mm in diameter, with a bevelled edge and no score, engraved with “D1” on one side and “NVR” on the other.
Spanish: Comprimidos redondos, planos, blancos a ligeramente amarillentos, de aproximadamente 7,1 mm de diámetro, con un borde biselado y sin ranura, con la inscripción «D1» en una cara y «NVR» en la otra.
English: Blood lipids
Spanish: Lípidos en sangre
English: White to slightly yellowish, round, flat tablets of approximately 10.1 mm in diameter, with a bevelled edge and no score, engraved with “D3” on one side and “NVR” on the other.
Spanish: Comprimidos redondos, planos, blancos a ligeramente amarillentos, de aproximadamente 10,1 mm de diámetro, con un borde biselado y sin ranura, con la inscripción «D3» en una cara y «NVR» en la otra.
English: White to slightly yellowish, round, flat tablets of approximately 9.1 mm in diameter, with a bevelled edge and no score, engraved with “D2” on one side and “NVR” on the other.
Spanish: Comprimidos redondos, planos, blancos a ligeramente amarillentos, de aproximadamente 9,1 mm de diámetro, con un borde biselado y sin ranura, con la inscripción «D2» en una cara y «NVR» en la otra.
English: How to store Votubia
Spanish: Conservación de Votubia
English: Response rates were 34.6% (95% CI: 24.2, 46.2) for the Votubia arm compared with 0% (95% CI: 0.0, 9.0) for the placebo arm (Table 7).
Spanish: Las tasas de respuesta fueron 34,6% (IC 95%: 24,2, 46,2) para el brazo de Votubia comparado con 0% (IC 95%: 0,0, 9,0) para el brazo de placebo (Tabla 7) Además, los 8 pacientes en el brazo de Votubia que presentaban evidencia radiográfica de hidrocefalia a nivel basal presentaron un descenso en el volumen ventricular ventricular.
English: What Votubia tablets contain
Spanish: Composición de Votubia comprimidos
English: SEGA patients receiving concomitant potent CYP3A4 inducers may require an increased Votubia dose to achieve
Spanish: Los pacientes con SEGA tratados con inductores potentes de CYP3A4 pueden requerir un aumento de la dosis de Votubia para alcanzar la misma exposición que los pacientes que no toman inductores potentes.
English: These signs are listed at the beginning of section 4.
Spanish: Estos signos se dan al principio de la sección 4.
English: • This can help to reduce the effects of this illness.
Spanish: • Esto puede ayudar a reducir los efectos de la enfermedad.
English: This causes the symptoms of the illness.
Spanish: Esto provoca los síntomas de la enfermedad.
English: Gender and race
Spanish: Sexo y raza
English: From a microbiological point of view, it is recommended that the product should be used immediately.
Spanish: Desde el punto de vista microbiológico, se recomienda utilizar el medicamento de manera inmediata.
English: Primary mNIS+7b
Spanish: Primaria mNIS+7b
English: The frequency of the adverse reactions is expressed according to the following categories:
Spanish: La frecuencia de las reacciones adversas se expresa según las categorías siguientes:
English: Onpattro is used in adults only.
Spanish: Onpattro solo se utiliza en adultos.
English: Do not mix or dilute with other medicinal products.
Spanish: No mezclar ni diluir con otros medicamentos.
English: What Onpattro is and what it is used for
Spanish: Qué es Onpattro y para qué se utiliza
English: Your healthcare professional will throw away any medicines that are no longer being used.
Spanish: Su profesional sanitario se deshará de los medicamentos que ya no se utilicen.
English: Read all of this leaflet carefully before you are given this medicine because it contains important information for you.
Spanish: Lea todo el prospecto detenidamente antes de recibir este medicamento, porque contiene información importante para usted.
English: • Amyloid can build up around the nerves, heart, and other places in the body, preventing them from working normally.
Spanish: • El amiloide se puede acumular en torno a los nervios, el corazón y otros lugares del cuerpo e impedir que trabajen con normalidad.
English: Your doctor will tell you whether your condition allows you to drive vehicles and use machines safely.
Spanish: El médico le dirá si su afección le permite conducir vehículos y utilizar máquinas con seguridad.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/18/1320/001
Spanish: NÚMERO(S) DE AUTORIZACIÓN DE COMERCIALIZACIÓN EU/1/18/1320/001
English: One additional patient had pre-existing anti-drug antibodies.
Spanish: Un paciente adicional presentaba anticuerpos antifármaco preexistentes.
English: Symptoms of vitamin A deficiency may include:
Spanish: Los síntomas de la deficiencia de vitamina A pueden incluir:
English: Dosing is based on actual body weight.
Spanish: La posología se basa en el peso corporal real.
English: Children and adolescents Onpattro is not recommended in children and adolescents under 18 years of age.
Spanish: Niños y adolescentes Onpattro no está recomendado en niños y adolescentes de menos de 18 años de edad.
English: If a dose is missed, Onpattro should be administered as soon as possible.
Spanish: Si se omite una dosis, se debe administrar Onpattro lo antes posible.
English: Greater than 95% of patisiran in the circulation is associated with lipid nanoparticles.
Spanish: Más del 95 % del patisirán de la circulación está asociado a nanopartículas lipídicas.
English: • Gently invert the bag to mix the solution.
Spanish: • Invierta la bolsa suavemente para mezclar la solución.
English: The infusion site should be monitored for possible infiltration during administration.
Spanish: Es necesario vigilar el lugar de la perfusión para detectar una posible infiltración durante la administración.
English: • Bupropion, a medicine used to treat depression or to help you to stop smoking
Spanish: • Bupropión, un medicamento utilizado para tratar la depresión o para ayudar a dejar de fumar.
English: The educational material for patients (a home infusion guide detailing the steps to undertake during home infusion) should include information about:
Spanish: El material informativo para los pacientes (una guía para la perfusión en el domicilio que detalla los pasos a seguir durante la perfusión en el domicilio) debe incluir información sobre:
English: • Requirements for home infusion, including availability and timely administration of the appropriate premedication;
Spanish: • Los requisitos para la perfusión en el domicilio del paciente, incluida la disponibilidad y administración oportuna de la premedicación apropiada.
English: • Discard vial if it has been frozen.
Spanish: • Deseche el vial si se ha congelado.
English: Less than 1% of patisiran in the administered dose was recovered intact in urine.
Spanish: Menos del 1 % del patisirán de la dosis administrada se recuperó intacto en la orina.
English: • The active substance is patisiran.
Spanish: • El principio activo es patisirán.
English: The diluted solution should be administered immediately after preparation.
Spanish: La dilución diluida se deberá administrar inmediatamente después de la preparación.
English: Required premedication
Spanish: Premedicación necesaria