FrancophonIA/ELRC3.0 huggingface dataset:
English: The most frequently (seen in ≥ 1 % of patients) reported adverse reactions associated with the use of olanzapine in clinical trials were somnolence, weight gain, eosinophilia, elevated prolactin, cholesterol, glucose and triglyceride levels (see section 4.4), glucosuria, increased appetite, dizziness, akathisia, parkinsonism, leukopenia, neutropenia (see section 4.4), dyskinesia, orthostatic hypotension, anticholinergic effects, transient asymptomatic elevations of hepatic aminotransferases (see section 4.4), rash, asthenia, fatigue, pyrexia, arthralgia, increased alkaline phosphatase, high gamma glutamyltransferase, high uric acid, high creatine phosphokinase and oedema.
Croatian: Najčešće prijavljene nuspojave (uočene u ≥ 1% bolesnika) povezane s primjenom olanzapina u kliničkim ispitivanjima bile su somnolencija, povećanje tjelesne težine, eozinofilija, povišene vrijednosti prolaktina, kolesterola, glukoze i triglicerida (vidjeti dio 4.4), glikozurija, povećan apetit, omaglica, akatizija, parkinsonizam, leukopenija, neutropenija (vidjeti dio 4.4), diskinezija, ortostatska hipotenzija, antikolinergički učinci, prolazni asimptomatski porasti vrijednosti jetrenih aminotransferaza (vidjeti dio 4.4), osip, astenija, umor, pireksija, artralgija, povišena razina alkalne fosfataze, visoka razina gama glutamiltransferaze, visoka razina mokraćne kiseline, visoka razina kreatin fosfokinaze i edem.
English: The concomitant administration of activated charcoal was shown to reduce the oral bioavailability of olanzapine by 50 to 60 %.
Croatian: Pokazalo se da istodobna primjena aktivnog ugljena smanjuje oralnu bioraspoloživost olanzapina za 50 do 60%.
English: During treatment for schizophrenia, manic episode and recurrence prevention in bipolar disorder, daily dosage may subsequently be adjusted on the basis of individual clinical status within the range 520 mg/day.
Croatian: Tijekom liječenja shizofrenije, epizode manije te prevencije relapsa bipolarnog poremećaja, dnevna doza se može naknadno podesiti na temelju kliničke slike pojedinog bolesnika u rasponu od 5 do 20 mg/dan.
English: The frequency terms listed are defined as follows: Very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 < 1/100), rare (≥ 1/10,000 to< 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the data available).
Croatian: Učestalost je definirana kako slijedi: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: The frequency terms listed are defined as follows: Very common (≥ 1/10), common (≥ 1/100 to <
Croatian: Navedene učestalosti definirane su kako slijedi: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10).
English: Standard procedures for management of overdose may be indicated (i.e. gastric lavage, administration of activated charcoal).
Croatian: Mogu biti indicirani standardni postupci za liječenje predoziranja (tj. ispiranje želuca, primjena aktivnog ugljena).
English: Warnings and precautions Talk to your doctor or pharmacist before you take Olanzapine Glenmark
Croatian: Obratite se svom liječniku ili ljekarniku prije nego uzmete lijek Olanzapine Glenmark.
English: Crospovidone Magnesium stearate
Croatian: krospovidon magnezijev stearat
English: During treatment with olanzapine in combination with lithium or divalproex, an increase of ≥ 7 % from baseline body weight occurred in 17.4 % of patients during acute treatment (up to 6 weeks).
Croatian: Tijekom liječenja olanzapinom u kombinaciji s litijem ili divalproeksom, porast tjelesne težine  7% od početne pojavio se u 17,4% bolesnika tijekom akutnog liječenja (do 6 tjedana).
English: However, as clinical experience with olanzapine in patients with concomitant illness is limited, caution is advised when prescribing for patients with prostatic hypertrophy, or paralytic ileus and related conditions.
Croatian: Međutim, kako je kliničko iskustvo s olanzapinom u bolesnika s konkomitantnom bolešću ograničeno, savjetuje se oprez pri propisivanju lijeka bolesnicima s hipertrofijom prostate ili paralitičkim ileusom i povezanim stanjima.
English: Cytochromes P450-CYP1A2 and P450-CYP2D6 contribute to the formation of the N-desmethyl and 2-hydroxymethyl metabolites, both exhibited significantly less in vivo pharmacological activity than olanzapine in animal studies.
Croatian: Citokromi P450-CYP1A2 i P450-CYP2D6 doprinose stvaranju N-dezmetil i 2-hidroksimetil metabolita te u ispitivanjima na životinjama oba pokazuju značajno manje in vivo farmakološko djelovanje od olanzapina.
English: Do not stop taking your tablets just because you feel better.
Croatian: Ako prestanete uzimati lijek Olanzapine Glenmark Nemojte prestati uzimati tablete samo zato jer se osjećate bolje.
English: Olanzapine should be used cautiously in patients who have a history of seizures or are subject to factors, which may lower the seizure threshold.
Croatian: Olanzapin treba oprezno primjenjivati u bolesnika imaju napadaje u anamnezi ili su izloženi čimbenicima koji mogu sniziti prag za napadaje.
English: Undesirable alterations in lipids have been observed in olanzapine-treated patients in placebocontrolled clinical trials (see section 4.8).
Croatian: Neželjene promjene vrijednosti lipida uočene su u bolesnika liječenih olanzapinom u placebom kontroliranim kliničkim ispitivanjima (vidjeti dio 4.8).
English: Long-term olanzapine treatment (up to 12 months) for recurrence prevention in patients with bipolar disorder was associated with an increase of ≥ 7 % from baseline body weight in 39.9 % of patients.
Croatian: Dugotrajno liječenje olanzapinom (do 12 mjeseci) radi prevencije relapsa u bolesnika s bipolarnim poremećajem bilo je povezano s povećanjem tjelesne težine  7% od početne tjelesne težine u 39,9% bolesnika.
English: Very common symptoms in overdose (> 10 % incidence) include tachycardia, agitation/ aggressiveness, dysarthria, various extrapyramidal symptoms, and reduced level of consciousness ranging from sedation to coma.
Croatian: Vrlo česti simptomi predoziranja (incidencija > 10%) obuhvaćaju tahikardiju, agitaciju/agresivnost, dizartriju, različite ekstrapiramidalne simptome te smanjenu razinu svijesti u rasponu od sedacije do kome.
English: 8 In clinical trials of up to 12 weeks, plasma prolactin concentrations exceeded the upper limit of normal range in approximately 30% of olanzapine treated patients with normal baseline prolactin value.
Croatian: 8 U kliničkim ispitivanjima u trajanju do 12 tjedana koncentracije prolaktina u plazmi prelazile su gornju granicu normalnog raspona u približno 30% bolesnika liječenih olanzapinom s normalnom početnom vrijednošću prolaktina.
English: Reversible neutropenia, thrombocytopenia, or anaemia developed in a few dogs treated with 8 or 10 mg/kg/day (total olanzapine exposure [AUC] is 12- to 15-fold greater than that of a man given a 12-mg dose).
Croatian: Reverzibilna neutropenija, trombocitopenija ili anemija razvile su se u malog broja pasa liječenih dozom od 8 ili 10 mg/kg/dan (ukupna izloženost olanzapinu [AUC] je 12 do 15 puta veća nego izloženost u čovjeka kojemu je dana doza od 12 mg).
English: In the study, the risk of olanzapine was comparable to the risk of atypical antipsychotics included in a pooled analysis.
Croatian: U ispitivanju je rizik povezan s olanzapinom bio usporediv s rizikom povezanim s atipičnim antipsihoticima uključenima u objedinjenu analizu.
English: New born infants exposed to antipsychotics (including olanzapine) during the third trimester of pregnancy are at risk of adverse reactions including extrapyramidal and/or withdrawal symptoms that may vary in severity and duration following delivery.
Croatian: U novorođenčadi izloženoj antipsihoticima (uključujući olanzapin) tijekom trećeg tromjesečja trudnoće postoji rizik od nastanka nuspojava, uključujući ekstrapiramidne simptome i/ili simptome ustezanja koji nakon poroda mogu varirati po težini i trajanju.
English: DRESS appears initially as flu-like symptoms with a rash on the face and then with an extended rash, high temperature, enlarged lymph nodes, increased levels of liver enzymes seen in blood tests and an increase in a type of white blood cell (eosinophilia).
Croatian: najprije nastupa u obliku simptoma nalik gripi praćenih osipom na licu, a zatim se javljaju proširen osip, visoka tjelesna temperatura, povećani limfni čvorovi, povišene vrijednosti jetrenih enzima vidljive u nalazima krvnih pretraga te povišene vrijednosti jedne vrste bijelih krvnih stanica (eozinofilija).
English: There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress, or feeding disorder.
Croatian: Postoje izvješća o agitaciji, hipertoniji, hipotoniji, tremoru, somnolenciji, respiratornom distresu ili poremećaju hranjenja.
English: Olanzapine Glenmark has been shown to prevent recurrence of these symptoms in patients with bipolar disorder whose manic episode has responded to olanzapine treatment.
Croatian: Pokazalo se da Olanzapine Glenmark sprječava ponavljanje tih simptoma u bolesnika s bipolarnim poremećajem u kojih je epizoda manije reagirala na liječenje olanzapinom.
English: 6.4 Special precautions for storage Store below 30C
Croatian: 6.4 Posebne mjere pri čuvanju lijeka Čuvati na temperaturi ispod 30°C.
English: Do not drink any alcohol if you have been given Olanzapine Glenmark as together with alcohol it may make you feel drowsy.
Croatian: Nemojte piti alkohol ako uzimate lijek Olanzapine Glenmark jer u kombinaciji s alkoholom može izazvati omamljenost.
English: 31, D - 82194 Gröbenzell, Germany
Croatian: Industriestr. 31, D-82194, Gröbenzell, Njemačka
English: Pharmacotherapeutic group: psycholeptics, diazepines, oxazepines, thiazepines and oxepines, ATC code N05A H03.
Croatian: Farmakoterapijska skupina: psiholeptici, diazepini, oksazepini, tiazepini i oksepini, ATK oznaka: N05AH03.
English: Patients treated with any antipsychotic medicines, including olanzapine, should be observed for signs and symptoms of hyperglycaemia (such as polydipsia, polyuria, polyphagia, and weakness) and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control.
Croatian: U bolesnika liječenih bilo kojim antipsihotikom, uključujući lijek Olanzapine Glenmark, treba pratiti pojavu znakova i simptoma hiperglikemije (kao što su polidipsija, poliurija, polifagija i slabost), a bolesnike s dijabetesom melitusom ili čimbenicima rizika za razvoj dijabetesa melitusa treba redovito pratiti zbog mogućeg pogoršanja glikemije.
English: Do not take Olanzapine Glenmark - if you are allergic (hypersensitive) to olanzapine or any of the other ingredients of this medicine (listed in section 6).
Croatian: • Ako ste alergični (preosjetljivi) na olanzapin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: - The use of Olanzapine Glenmark in elderly patients with dementia is not recommended as it may have serious side effects.
Croatian: • Primjena lijeka Olanzapine Glenmark u starijih bolesnika s demencijom (zaboravljivošću) se ne preporučuje jer mogu nastati teške nuspojave.
English: 70 tablets
Croatian: 70 tableta
English: In clinical trials in patients with drug-induced (dopamine agonist) psychosis associated with Parkinson's disease, worsening of Parkinsonian symptomatology and hallucinations were reported very commonly and more frequently than with placebo.
Croatian: U kliničkim ispitivanjima u bolesnika s psihozom uzrokovanom lijekovima (agonisti dopamina) povezanom s Parkinsonovom bolešću vrlo često je zabilježeno pogoršanje simptoma parkinsonizma i halucinacija i češće nego s placebom.
English: Other medically significant sequelae of overdose include delirium, convulsion, coma, possible neuroleptic malignant syndrome, respiratory depression, aspiration, hypertension or hypotension, cardiac arrhythmias (< 2 % of overdose cases) and cardiopulmonary arrest.
Croatian: Druge medicinski značajne posljedice predoziranja obuhvaćaju delirij, konvulzije, komu, mogući neuroleptički maligni sindrom, respiratornu depresiju, aspiraciju, hipertenziju ili hipotenziju, srčane aritmije (< 2% slučajeva predoziranja) i kardiopulmonalni arest.
English: You should swallow the Olanzapine Glenmark tablets whole, with water.
Croatian: Olanzapine Glenmark tablete morate progutati cijele s vodom.
English: The clinical consequences are likely to be limited, but clinical monitoring is recommended and an increase of olanzapine dose may be considered if necessary (see section 4.2).
Croatian: Kliničke posljedice su vjerojatno ograničene, ali se preporučuje kliničko praćenje te se može razmotriti povećanje doze olanzapina, ako je to potrebno (vidjeti dio 4.2).
English: In cytopenic dogs, there were no adverse effects on progenitor and proliferating cells in the bone marrow.
Croatian: U pasa s citopenijom nije bilo štetnih učinaka za matične i proliferacijske stanice koštane srži.
English: If this happens after you have been given Olanzapine Glenmark tell your doctor.
Croatian: Ako Vam se ovo pojavi nakon uzimanja lijeka Olanzapine Glenmark, obratite se svom liječniku.
English: If you suddenly stop taking Olanzapine Glenmark, symptoms such as sweating, unable to sleep, tremor, anxiety or nausea and vomiting might occur.
Croatian: Ako naglo prestanete s uzimanjem lijeka Olanzapine Glenmark mogu se pojaviti simptomi poput znojenja, nesanice, nevoljnog drhtanja, tjeskobe ili mučnine i povraćanja.
English: - Very rarely, medicines of this type cause a combination of fever, faster breathing, sweating, muscle stiffness and drowsiness or sleepiness.
Croatian: • Vrlo rijetko lijekovi ovog tipa uzrokuju kombinaciju vrućice, ubrzanog disanja, znojenja, ukočenosti mišića te omamljenosti ili pospanosti.
English: Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i blisteru iza oznake "Rok valjanosti".
English: High Gamma Glutamyltransferase High uric acid 10
Croatian: visoka gama glutamiltransferaza visoka razina mokraćne kiseline10
English: 10 As assessed by measured values from clinical trials in the Olanzapine Integrated Database.
Croatian: 10 Procijenjeno na temelju izmjerenih vrijednosti iz kliničkih ispitivanja u integriranoj bazi podataka za olanzapin.
English: • Serious allergic reactions such as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
Croatian: Vrlo rijetke nuspojave uključuju ozbiljne alergijske reakcije poput reakcije na lijek uz eozinofiliju i sistemske simptome (engl. drug reaction with eosinophilia and systemic symptoms, DRESS).
English: Caution should be exercised and follow-up organised in patients with elevated ALT and/or AST, in patients with signs and symptoms of hepatic impairment, in patients with pre-existing conditions associated with limited hepatic functional reserve, and in patients who are being treated with potentially hepatotoxic medicines.
Croatian: Potreban je oprez i kontrola u bolesnika s povišenim ALT-om i/ili ASTom, u bolesnika sa znakovima i simptomima oštećenja jetre, u bolesnika s prethodno postojećim stanjima povezanima s ograničenom funkcionalnom rezervom jetre te u bolesnika koji se liječe potencijalno hepatotoksičnim lijekovima.
English: 6 In clinical trials, the incidence of Parkinsonism and dystonia in olanzapine-treated patients was numerically higher, but not statistically significantly different from placebo.
Croatian: 6 U kliničkim ispitivanjima incidencija parkinsonizma i distonije u bolesnika liječenih olanzapinom bila je brojčano veća, ali nije bila statistički značajno različita u odnosu na placebo.
English: Other medicines and Olanzapine Glenmark
Croatian: Drugi lijekovi i Olanzapine Glenmark
English: Effects on haematology parameters were found in each species, including dose-related reductions in circulating leukocytes in mice and non-specific reductions of circulating leukocytes in rats; however, no evidence of bone marrow cytotoxicity was found.
Croatian: U svakoj su vrsti pronađeni učinci na hematološke parametre, uključujući smanjenje broja cirkulirajućih leukocita ovisno o dozi u miševa te nespecifično smanjenje broja cirkulirajućih leukocita u štakora.
English: All olanzapine and placebo-treated patients who experienced a cerebrovascular event had pre-existing risk factors.
Croatian: Svi bolesnici liječeni olanzapinom i bolesnici koji su primali placebo, a u kojih se javio cerebrovaskularni događaj, prethodno su imali čimbenike rizika.
English: The following table summarises the adverse reactions reported with a greater frequency in adolescent patients (aged 13-17 years) than in adult patients or adverse reactions only identified during short-term clinical trials in adolescent patients.
Croatian: Sljedeća tablica sažima nuspojave prijavljene s većom učestalošću u adolescentnih bolesnika (u dobi od 13 do 17 godina) u odnosu na odrasle bolesnike ili nuspojave identificirane samo u kratkotrajnim kliničkim ispitivanjima u adolescentnih bolesnika.
English: In renally impaired patients (creatinine clearance < 10 ml/min) versus healthy subjects, there was no significant difference in mean elimination half-life (37.7 versus 32.4 hr) or clearance (21.2 versus 25.0 l/hr).
Croatian: U bolesnika s oštećenjem bubrega (klirens kreatinina < 10 ml/min) nije bilo značajne razlike u odnosu na zdrave ispitanike u prosječnom poluvremenu eliminacije (37,7 naspram 32,4 sata) ili klirensu (21,2 naspram 25,0 l/h).
English: Thus no particular interaction is expected as verified through in vivo studies where no inhibition of metabolism of the following active substances was found: tricyclic antidepressant (representing mostly CYP2D6 pathway), warfarin (CYP2C9), theophylline (CYP1A2) or diazepam (CYP3A4 and CYP2C19).
Croatian: Stoga se ne očekuje nikakva posebna interakcija, što potvrđuju in vivo ispitivanja u kojima nije nađena inhibicija metabolizma sljedećih djelatnih tvari: tricikličkih antidepresiva (predstavljaju glavninu CYP2D6 puta), varfarina (CYP2C9), teofilina (CYP1A2) ili diazepama (CYP3A4 i 2C19).
English: 12 Adverse event identified from spontaneous post-marketing reporting with frequency estimated at the upper limit of the 95% confidence interval utilising the Olanzapine Integrated Database.
Croatian: 12 Nuspojava je identificirana iz spontanih prijava nakon stavljanja lijeka u promet, a učestalost je određena na gornjoj granici 95%-tnog intervala pouzdanosti uz pomoć integrirane baze podataka za olanzapin.
English: Caution should be exercised in patients with low leukocyte and/or neutrophil counts for any reason, in patients receiving medicines known to cause neutropenia, in patients with a history of drug-induced bone marrow depression/toxicity, in patients with bone marrow depression caused by concomitant illness, radiation therapy or chemotherapy and in patients with hypereosinophilic conditions or with myeloproliferative disease.
Croatian: Oprez je potreban u bolesnika s niskim brojem leukocita i/ili neutrofila iz bilo kojeg razloga, u bolesnika koji primaju lijekove za koje se zna da uzrokuju neutropeniju, u bolesnika s depresijom/toksičnošću koštane srži uzrokovane lijekovima u anamnezi, u bolesnika s depresijom koštane srži uzrokovanom popratnom bolešću, zračenjem ili kemoterapijom te u bolesnika s hipereozinofilnim stanjima ili mijeloproliferativnom bolešću.
English: Olanzapine Glenmark with alcohol
Croatian: Olanzapine Glenmarks alkoholom
English: In a multinational, double-blind, comparative study of schizophrenia, schizoaffective, and related disorders which included 1,481 patients with varying degrees of associated depressive symptoms (baseline mean of 16.6 on the Montgomery-Asberg Depression Rating Scale), a prospective secondary analysis of baseline to endpoint mood score change demonstrated a statistically significant\ improvement (p= 0.001) favouring olanzapine (- 6.0) versus haloperidol (- 3.1).
Croatian: U multinacionalnom, dvostruko slijepom, komparativnom ispitivanju shizofrenije, shizoafektivnih i povezanih poremećaja, koje je obuhvaćalo 1481 bolesnika s različitim stupnjevima pridruženih simptoma depresije (srednja početna vrijednost 16,6 po Montgomery-Asberg ljestvici depresije), prospektivna sekundarna analiza vrijednosti promjene raspoloženja od početnog do krajnjeg pokazala je statistički značajno poboljšanje (p=0,001) u korist olanzapina (-6,0) u odnosu na haloperidol (-3,1).
English: In a study in breast- feeding, healthy women, olanzapine was excreted in breast milk.
Croatian: U ispitivanju sa zdravim dojiljama olanzapin se izlučivao u majčino mlijeko.
English: In clinical trials, clinically meaningful QTc prolongations (Fridericia QT correction [QTcF] ≥ 500 milliseconds [msec] at any time post baseline in patients with baseline QTcF < 500 msec) were uncommon (0.1 % to 1 %) in patients treated with olanzapine, with no significant differences in associated cardiac events compared to placebo.
Croatian: U kliničkim ispitivanjima klinički značajna produljenja QTc intervala (Fridericia QT korekcija [QTcF] ≥ 500 milisekundi [ms] bilo kada nakon početne vrijednosti u bolesnika s početnom vrijednošću QTcF< 500 ms) bila su manje česta (0,1% do 1%) u bolesnika liječenih olanzapinom, bez značajnih razlika u povezanim srčanim događajima u usporedbi s placebom.
English: Hyperglycaemia and/or development or exacerbation of diabetes occasionally associated with ketoacidosis or coma has been reported uncommonly, including some fatal cases (see section 4.8).
Croatian: Manje su često prijavljivane hiperglikemija i/ili razvoj ili egzacerbacija dijabetesa ponekad povezani s ketoacidozom ili komom, uključujući neke smrtne slučajeve (vidjeti dio 4.8).
English: Patients treated with any antipsychotic medicines, including olanzapine, should be monitored regularly for lipids in accordance with utilised antipsychotic guidelines e.g. at baseline, 12 weeks after starting olanzapine treatment and every 5 years thereafter.
Croatian: U bolesnika liječenih bilo kojim antipsihotikom, uključujući lijek Olanzapine Glenmark, potrebno je redovito pratiti razinu lipida prema smjernicama za primjenu antipsihotika, na primjer, na početku liječenja, 12 tjedana nakon početka liječenja olanzapinom te svakih 5 godina nakon toga.
English: - The other ingredients are mannitol (E 421), microcrystalline cellulose, aspartame (E 951), crospovidone, magnesium stearate
Croatian: - Drugi sastojci su: manitol (E421), mikrokristalična celuloza, aspartam (E951), krospovidon,
English: - Weight gain has been seen in patients taking Olanzapine Glenmark.
Croatian: • Zapaženo je povećanje tjelesne težine u bolesnika koji uzimaju lijek Olanzapine Glenmark.
English: Temporal association of olanzapine treatment and venous thromboembolism has been reported uncommonly (≥ 0.1% and < 1%).
Croatian: Vremenska povezanost liječenja olanzapinom i venske tromboembolije (VTE) prijavljivana je manje često (< 0,01% i < 1%).
English: Olanzapine Glenmark tablet contains aspartame, which is a source of phenylalanine.
Croatian: Olanzapin Glenmark tablete sadrže aspartam, koji je izvor fenilalanina.
English: In a single oral dose (10 mg) Positron Emission Tomography (PET) study in healthy volunteers, olanzapine produced a higher 5HT2A than dopamine D2 receptor occupancy.
Croatian: U ispitivanju pozitronskom emisijskom tomografijom (PET), jedna peroralna doza (10 mg) olanzapina u zdravih dobrovoljaca dovela je do većeg zauzimanja 5HT2A nego dopaminskih D2 receptora.
English: What you need to know before you take Olanzapine Glenmark
Croatian: Što morate znati prije nego počnete uzimati lijek Olanzapine Glenmark
English: However, caution should be exercised when olanzapine is prescribed with medicines known to increase QTc interval, especially in the elderly, in patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalaemia or hypomagnesaemia.
Croatian: Međutim, oprez je potreban prilikom propisivanja olanzapina s lijekovima za koje se zna da produljuju QTc-interval, osobito u starijih osoba, u bolesnika s prirođenim sindromom dugog QT-intervala, kongestivnim zatajenjem srca, hipertrofijom srca, hipokalijemijom ili hipomagnezijemijom.