FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients who have previously received a hematopoietic stem cell transplant (HSCT) may be at higher risk for hepatotoxicity suggestive of veno-occlusive disease (VOD) following treatment with clofarabine (40 mg/m2) when used in combination with etoposide (100 mg/m2) and cyclophosphamide
Croatian: U bolesnika kod kojih je prethodno učinjena transplantacija krvotvornih matičnih stanica (TKMS) može postojati povećan rizik od hepatotoksičnosti, koja upućuje na venskookluzivnu bolest (VOB), nakon liječenja klofarabinom (40 mg/m2) kada se primjenjuje u kombinaciji s etopozidom (100 mg/m2) i ciklofosfamidom (440 mg/m2).
English: If persistent leukaemia is not evident, it is recommended that the dose for the next cycle be reduced by 25% of the previous dose following recovery of ANC to ≥ 0.75 × 10
Croatian: Ako nema znakova perzistentne leukemije, za sljedeći se ciklus nakon oporavka ABN na ≥ 0,75 × 109/l preporučuje smanjiti dozu za 25% u odnosu na prethodnu.
English: The MAH shall provide yearly updates on any new information concerning efficacy and safety of the product in paediatric patients with acute lymphoblastic leukaemia who have relapsed or are refractory after receiving at least two prior regimens and where there is no other treatment option anticipated to result in a durable response.
Croatian: Nositelj odobrenja će podnositi godišnja ažuriranja o svim novim informacijama o djelotvornosti i sigurnosti lijeka u pedijatrijskih bolesnika s akutnom limfoblastičnom leukemijom u kojih je došlo do relapsa ili je bolest refraktorna nakon najmanje dvije prethodne linije liječenja i kada ne postoji druga mogućnost liječenja koja bi dovela do trajnijeg odgovora.
English: If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2
Croatian: Ako se ne primijeni odmah, vrijeme i uvjeti čuvanja lijeka prije primjene odgovornost su korisnika.
English: Evoltra contains the active substance clofarabine.
Croatian: Evoltra sadrži djelatnu tvar klofarabin.
English: These effects included bilateral degeneration of the seminiferous epithelium with retained spermatids and atrophy of interstitial cells in rats at exaggerated exposure levels (150 mg/m2/day), and cell degeneration of the epididymis and degeneration of the seminiferous epithelium in dogs at clinically relevant exposure levels (> 7.5 mg/m2/day clofarabine).
Croatian: Među njih se ubrajaju bilateralna degeneracija epitela sjemenovoda (150 mg/m2/dan) i atrofija intersticijskih stanica u štakora kod izloženosti prekomjernim dozama (150 mg/m2 na dan) te stanična degeneracija epididimisa i degeneracija epitela sjemenovoda u pasa pri klinički značajnim razinama izloženosti (doza klofarabina od ≥ 7,5 mg/m2 na dan).
English: Luxembourg/Luxemburg Sanofi Belgium Tél/Tel: + 32 2 710 54 00 (Belgique/Belgien)
Croatian: Sanofi Belgium Tél/Tel: + 32 2 710 54 00 (Belgique/Belgien)
English: Patients with cardiac disease and those taking medicinal products known to affect blood pressure or cardiac function should be closely monitored during treatment with clofarabine (see sections 4.5 and 4.8).
Croatian: Bolesnike sa srčanom bolešću i one koji uzimaju lijekove za koje se zna da utječu na krvni tlak ili srčanu funkciju treba pažljivo nadzirati tijekom liječenja klofarabinom (vidjeti dijelove 4.5 i 4.8).
English: - water collecting around the heart, fast heartbeat; - low blood pressure, lump due to bad bruising; - leaking from tiny blood vessels, rapid breathing, nosebleeds, breathing difficulties,
Croatian: - nizak krvni tlak, nastanak oteklina zbog jakih podljeva krvi; - krvarenje iz malih krvnih žila, ubrzano disanje, krvarenje iz nosa, otežano disanje, nedostatak zraka,
English: How to store Evoltra
Croatian: Kako čuvati lijek Evoltra
English: Dose reduction for patients experiencing non-haematological toxicities Infectious events
Croatian: Smanjenje doze u bolesnika u kojih je došlo do nehematološke toksičnosti Infektivni događaji
English: Fifty percent of patients experienced at least one cardiac disorders adverse event.
Croatian: Srčani poremećaji U 50% bolesnika zabilježen je barem jedan štetni događaj u obliku srčanog poremećaja.
English: Evoltra 1 mg/ml concentrate for solution for infusion must be diluted prior to administration.
Croatian: Evoltra 1 mg/ml koncentrat za otopinu za infuziju mora se razrijediti prije primjene.
English: The use of disposable gloves and protective garments is recommended when handling Evoltra.
Croatian: Pri rukovanju lijekom Evoltra preporučuje se uporaba jednokratnih rukavica i zaštitne odjeće.
English: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), including fatal cases, have been reported (see section 4.8).
Croatian: Poremećaji kože i potkožnog tkiva Prijavljeni su Stevens-Johnsonov sindrom (SJS) i toksična epidermalna nekroliza (TEN), uključujući i smrtne slučajeve (vidjeti dio 4.8).
English: The safety profile of clofarabine has not been established in patients with severe renal impairment or patients receiving renal replacement therapy (see section 4.3).
Croatian: Sigurnosni profil klofarabina nije utvrđen u bolesnika s teškim oštećenjem bubrežne funkcije niti u bolesnika koji primaju bubrežno nadomjesno liječenje (vidjeti dio 4.3).
English: Dosing commenced at 11.25 with escalation to 15, 30, 40, 52 and 70 mg/m2/day by intravenous infusion for 5 days every
Croatian: 15, 30, 40, 52 i 70 mg/m2 na dan, a primjenjivala se intravenskom infuzijom tijekom 5 dana svakih
English: This is equivalent to 3.08 mmol (or 70.77 mg) of sodium.
Croatian: Jedna bočica sadrži 180 mg soli (natrijevog klorida), što odgovara količini od 3,08 mmol (ili 70,77 mg) natrija.
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2).
Croatian: Lijek se izdaje na ograničeni recept (vidjeti Dodatak I: Sažetak opisa svojstava lijeka, dio 4.2)
English: Common: Hyperbilirubinaemia, jaundice, venoocclusive disease, increases in alanine (ALT)* and aspartate (AST)* aminotransferases, hepatic failure Uncommon: Hepatitis
Croatian: Poremećaji jetre i žuči često: hiperbilirubinemija, žutica, venskookluzivna bolest, povišene vrijednosti alanin aminotransferaze (ALT)* i aspartat aminotransferaze (AST)*, zatajenje jetre manje često: hepatitis
English: Common: Anorexia, decreased appetite, dehydration Frequency not known: hyponatremia
Croatian: Poremećaji metabolizma i prehrane često: anoreksija, smanjen tek, dehidracija nepoznata učestalost: hiponatrijemija
English: 37 Hollands Road
Croatian: Paasheuvelweg 25
English: 9/l for more than 4 weeks from the start of the last cycle, it is recommended that the dose for the next cycle be reduced by 25%.
Croatian: Ako u bolesnika ABN iznosi < 0,5 × 109/l dulje od 4 tjedna nakon početka posljednjeg ciklusa liječenja, u sljedećem se ciklusu preporučuje smanjiti dozu za 25%.
English: Four renal adverse events in 115 patients were considered to be related to clofarabine, none of which were serious; haematuria (3 events) and acute renal failure (1 event) (see sections 4.3 and 4.4).
Croatian: Četiri bubrežna štetna događaja prijavljena u 115 bolesnika smatrana su povezanima s klofarabinom, ali nijedan nije bio ozbiljan: hematurija (3 događaja) i akutno zatajenje bubrega (1 događaj) (vidjeti dijelove 4.3 i 4.4).
English: Twentythree patients out of 115 experienced a vascular disorder considered to be related to clofarabine, the most frequently reported being flushing (13 events; not serious) and hypotension (5 events; all of which were considered to be serious; see section 4.4).
Croatian: od 115 bolesnika javili su se krvožilni poremećaji koji se smatraju povezanima s klofarabinom, a među njima su najčešće prijavljivani bili navale crvenila (13 događaja; nisu bili ozbiljni) i hipotenzija (5 događaja; svi su se smatrali ozbiljnima; vidjeti dio 4.4).
English: Evoltra 1 mg/ml concentrate for solution for infusion
Croatian: Evoltra 1 mg/ml koncentrat za otopinu za infuziju
English: Sixty-four patients of 115 (55.7%) experienced at least one vascular disorders adverse event.
Croatian: U 64 od 115 bolesnika (55,7%) javio se barem jedan štetni događaj u obliku krvožilnog poremećaja.
English: The diluted concentrate is chemically and physically stable for 3 days at 2
Croatian: Razrijeđeni koncentrat je kemijski i fizikalno stabilan tijekom 3 dana na temperaturi od 2°C do 8°C te na sobnoj temperaturi (do 25°C).
English: Forty-one patients of 115 (35.7%) experienced at least one renal and urinary disorders adverse event.
Croatian: U 41 od 115 bolesnika (35,7%) javio se barem jedan štetni događaj u obliku poremećaja bubrega i mokraćnog sustava.
English: The safety and efficacy of clofarabine were evaluated in a phase I, open-label, non-comparative, dose-escalation study in 25 paediatric patients with relapsed or refractory leukaemia (17 ALL; 8 AML) who had failed standard therapy or for whom no other therapy existed.
Croatian: • (broj bolesnika s KR-om + broj bolesnika s KRt-om) ÷ broj bolesnika dostupnih za ocjenu koji su primili klofarabin Sigurnost i djelotvornost klofarabina procijenjene su u otvorenom, nekomparativnom ispitivanju faze I s povećavanjem doze u kojemu je sudjelovalo 25 pedijatrijskih bolesnika s relapsnom ili refraktornom leukemijom (17 ALL; 8 AML) u kojih standardno liječenje nije bilo učinkovito ili za koje nije postojalo drugo liječenje.
English: How to use Evoltra
Croatian: Kako primjenjivati lijek Evoltra
English: Type I glass vial with bromobutyl rubber stopper, polypropylene flip-off cap and aluminium overseal.
Croatian: I s brombutilnim gumenim čepom, polipropilenskom "flip-off" kapicom i aluminijskim prstenom.
English: Overall Remission (OR) Rate
Croatian: Stopa ukupne remisije (UR)
English: The no-observable effect level for maternal toxicity in rats was 18 mg/m 2/day and in rabbits was more than
Croatian: Razina izloženosti pri kojoj nisu uočeni štetni učinci za majku bila je 18 mg/m2 na dan u štakora te više od 12 mg/m2 na dan u kunića.
English: Evoltra 1 mg/ml concentrate for solution for infusion clofarabine
Croatian: Evoltra 1 mg/ml koncentrat za otopinu za infuziju klofarabin
English: Evoltra is used to treat children (≥ 1 year old), teenagers and young adults up to 21 years old with acute lymphoblastic leukaemia (ALL) when previous treatments have not worked or have stopped working.
Croatian: Evoltra se koristi za liječenje djece (u dobi ≥ 1 godine), tinejdžera i mladih odraslih ljudi u dobi do 21
English: Vistor hf.
Croatian: KRt KR KRt KR
English: Genzyme Europe BV Paasheuvelweg 25
Croatian: Genzyme Europe BV Paasheuvelweg 25 1105 BP Amsterdam Nizozemska
English: The concomitant use of medicinal products that have been associated with renal toxicity and those eliminated by tubular secretion such as NSAIDs, amphotericin B, methotrexate, aminosides, organoplatines, foscarnet, pentamidine, cyclosporin, tacrolimus, acyclovir and valganciclovir, should be avoided particularly during the 5 day clofarabine administration period; preference should be given to those medicinal products that are not known to be nephrotoxic (see sections 4.5 and 4.8).
Croatian: spojevi platine, foskarnet, pentamidin, ciklosporin, takrolimus, aciklovir i valganciklovir, naročito tijekom petodnevnog razdoblja primjene klofarabina; prednost treba dati onim lijekovima za koje se zna da nisu nefrotoksični (vidjeti dijelove 4.5 i 4.8).
English: Children and adolescents (≥ 1 year old) The recommended dose in monotherapy is 52 mg/m of body surface area administered by intravenous infusion over 2 hours daily for 5 consecutive days.
Croatian: Preporučena doza u monoterapiji je 52 mg/m2 tjelesne površine primijenjena intravenskom infuzijom tijekom 2 sata na dan kroz 5 uzastopnih dana.
English: Excipients: Sodium chloride and water for injections.
Croatian: POPIS POMOĆNIH TVARI Pomoćne tvari: natrijev klorid i voda za injekcije.
English: Very common: Vomiting, nausea, diarrhoea Common: Mouth haemorrhage, gingival bleeding, haematemesis, abdominal pain, stomatitis, upper abdominal pain, proctalgia, mouth ulceration Frequency not known: Pancreatitis elevations in serum amylase and lipase, enterocolitis, neutropaenic colitis, caecitis
Croatian: Poremećaji probavnog sustava vrlo često: povraćanje, mučnina, proljev često: krvarenje u ustima, krvarenje iz desni, hematemeza, bol u abdomenu, stomatitis, bol u gornjem dijelu abdomena, proktalgija, ulceracije usne šupljine učestalost nepoznata: pankreatitis, povišene vrijednosti amilaza i lipaza u serumu, enterokolitis, neutropenijski kolitis, tiflitis
English: CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE USE OF THE MEDICINAL PRODUCT
Croatian: UVJETI ILI OGRANIČENJA VEZANI UZ SIGURNU I UČINKOVITU PRIMJENU LIJEKA • Plan upravljanja rizikom (RMP)
English: • At the request of the European Medicines Agency
Croatian: Nadopunjeni RMP treba dostaviti: • Na zahtjev Europske agencije za lijekove;
English: This is usually reversible and appears to be dosedependent.
Croatian: Supresija koštane srži je očekivana no uglavnom reverzibilna, a čini se da ovisi o dozi.
English: weight loss; - agitation, irritability, or restlessness; - feeling numb or weak in the arms and legs, numbness of the skin, sleepiness, dizziness, tremor; - hearing problems;
Croatian: - osjećaj žeđi, tamnija mokraća ili izlučivanje manje količine mokraće nego inače, smanjen tek ili gubitak teka, gubitak tjelesne težine; - uznemirenost, razdražljivost ili nemir - utrnulost ili slabost u rukama i nogama, utrnulost kože, pospanost, omaglica, nevoljno drhtanje; - tegobe sa sluhom;
English: België/Belgique/Belgien/ Sanofi Belgium Tél/Tel: + 32 2 710 54 00
Croatian: Sanofi Belgium Tél/Tel: + 32 2 710 54 00
English: °C unless dilution has taken place under controlled and validated aseptic conditions.
Croatian: Lijek pripremljen za primjenu ne bi se smio čuvati dulje od 24 sata na temperaturi od 2°C do 8°C, osim ako razrjeđivanje nije provedeno u kontroliranim i validiranim aseptičkim uvjetima.
English: oC to 8 oC).
Croatian: (vidjeti dio 4.8).
English: Each vial of Evoltra contains 180 mg of sodium chloride.
Croatian: Jedna bočica od 20 ml sadrži 180 mg natrijevog klorida.
English: Each ml of concentrate contains 1 mg of clofarabine.
Croatian: Jedan ml koncentrata sadrži 1 mg klofarabina.
English: Evoltra is a potent antineoplastic agent with potentially significant haematological and non-haematological adverse reactions (see section 4.8).
Croatian: Evoltra je snažan antineoplastik koji može izazvati značajne hematološke i nehematološke nuspojave
English: Increases in postimplantation loss, reduced foetal body weights and decreased litter sizes together with increases in the number of malformations (gross external, soft tissue) and skeletal alterations (including retarded ossification) were reported in rats receiving doses which produced approximately 2 to 3 fold the clinical exposure (54 mg/m2/day) and in rabbits receiving 12 mg/m 2/day clofarabine.
Croatian: U štakora koji su primali doze koje su dovele do izloženosti približno 2 do 3 puta veće od one kliničke (54 mg/m2 na dan) te u kunića koji su primali dozu klofarabina od 12 mg/m2 na dan prijavljena je povećana učestalost gubitka ploda nakon implantacije, smanjena tjelesna težina ploda i smanjena veličina legla, uz povećanje broja malformacija (velike vanjske, meko tkivo) i koštanih promjena (uključujući zastoj u osifikaciji).
English: If you use more Evoltra than you should If you think you may have been given too much medicine, tell your doctor straight away.
Croatian: Ako mislite da ste primili previše lijeka, odmah se obratite svome liječniku.
English: • Recovery of peripheral counts (platelets  100 x 10
Croatian: • oporavak broja perifernih stanica (trombociti ≥ 100 x 109/l i ABN ≥ 1,0 x 109/l)
English: Very common (may affect more than 1 in 10 people): anxiety, headache, fever, tiredness; feeling and being sick, diarrhoea (loose bowels); flushing, itching and inflamed skin, inflammation of mucus (moist) linings such as the mouth and other areas; you may have more infections than normal because Evoltra can lower the number of certain types of blood cells in your body; skin rashes which may be itchy, red, painful or peeling skin including palms of the hands and soles of the feet, or small reddish or purple spots underneath the skin.
Croatian: - možete imati više infekcija nego obično jer Evoltra može sniziti broj nekih vrsta krvnih stanica u tijelu; - kožni osip koji može svrbjeti, biti crven ili bolan, ljuštenje kože, uključujući dlanove i tabane, male crvenkaste ili ljubičaste mrlje ispod kože.
English: Very common: Febrile neutropaenia Common: Neutropaenia
Croatian: Poremećaji krvi i limfnog sustava vrlo često: neutropenijska vrućica često: neutropenija
English: 12 mg/m 2/day.
Croatian: 52 mg/m2/dan
English: Do not use Evoltra: - if you are allergic to clofarabine or any of the other ingredients of this medicine (listed in section 6); - if you are breast-feeding (please read the section “Pregnancy and breast-feeding” below); - if you have severe kidney or liver problems.
Croatian: - ako dojite (molimo pročitajte dio "Trudnoća i dojenje" u nastavku);
English: What Evoltra contains
Croatian: MATERIJALA KOJI POTJEČU
English: Hepatic impairment
Croatian: - upala jetre (hepatitis).
English: If a patient experiences a hematologic toxicity of Grade 4 neutropaenia (ANC < 0.5 x 10
Croatian: Ako se u bolesnika pojavi hematološka toksičnost u obliku neutropenije 4. stupnja (ABN < 0,5 x 109/l) u trajanju od ≥ 4 tjedana, u sljedećem ciklusu dozu treba smanjiti za 25%.
English: *Each ml of concentrate contains 1 mg of clofarabine.
Croatian: 200 ml *Jedan ml koncentrata sadrži 1 mg klofarabina.
English: What Evoltra looks like and contents of the pack Evoltra is a concentrate for solution for infusion.
Croatian: Kako Evoltra izgleda i sadržaj pakiranja
English: Tell your doctor if any of these apply to you.
Croatian: Ako se bilo što od navedenog odnosi na Vas, obavijestite svog liječnika.
English: Cytotoxic
Croatian: hematom
English: The maximum tolerated dose identified in the phase I study described above of 52 mg/m2/day clofarabine was administered by intravenous infusion for 5 consecutive days every 2 to 6 weeks.
Croatian: iznosila je 52 mg/m2 na dan, a primjenjivana je intravenskom infuzijom tijekom 5 uzastopnih dana svakih
English: - if you have heart disease, or used to have it.
Croatian: - ako imate mučninu ili proljev;
English: Uncommon side effects (may affect up to 1 in 100 people): - inflammation of the liver (hepatitis).
Croatian: Manje česte nuspojave (mogu se javiti u manje od 1 na 100 osoba):
English: Common (may affect up to 1 in 10 people): - infections of the blood, pneumonia, shingles, implant infections, infections of the mouth such as thrush and cold sores; - changes in blood chemistry, changes in white blood cells; - allergic reactions; - feeling thirsty and producing darker or less urine than normal, decreased or loss of appetite,
Croatian: - žutilo kože i očiju (poznato i kao žutica) ili drugi poremećaji jetre; - nastanak modrica, gubitak kose, promjene boje kože, pojačano znojenje, suha koža ili druge tegobe s kožom;
English: The dose depends on the animal's weight.
Croatian: Doza ovisi o tjelesnoj težini životinje.
English: Further information on Credelio can be found on the Agency's website: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
Croatian: Više informacija o VMP-u Credelio nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
English: This overview was last updated in April 2018.
Croatian: Ovaj pregled informacija posljednji je put ažuriran u 4. 2018.
English: Credelio is effective for one month and treatment can be repeated every month.
Croatian: Credelio je učinkovit tijekom jednog mjeseca, a liječenje se može ponoviti svakog mjeseca.
English: It blocks the normal movement of charged particles in and out of nerve cells, especially those associated with gamma-aminobutyric acid (GABA) and glutamate, two substances that convey messages between nerves (neurotransmitters).
Croatian: Onemogućuje normalno kretanje nabijenih čestica u živčane stanice i iz njih, osobito onih povezanih s gama-aminobutiričnom kiselinom (GABA) i glutamatom, dvjema tvarima koje prenose poruke između živaca (neurotransmiteri).
English: This means that it kills parasites that live on the skin or in the fur of animals, such as fleas and ticks.
Croatian: To znači da ubija parazite koji žive na koži ili u krznu životinja, poput buha i krpelja.
English: In all studies below animals had natural infestations.
Croatian: U svim ispitivanjima navedenima u nastavku životinje su bile prirodno izložene infestacijama.
English: Other information about Credelio
Croatian: Ostale informacije o VMP-u Credelio
English: In order to be exposed to the active substance, fleas and ticks must have attached to the skin and commenced feeding on the animal's blood.
Croatian: Kako bi ih se izložilo djelatnoj tvari, buhe i krpelji moraju biti pričvršćeni na kožu i početi se hraniti krvlju životinje.
English: Credelio received a marketing authorisation valid throughout the EU on 25 April 2017.
Croatian: Za VMP Credelio izdano je odobrenje za stavljanje u promet koje je na snazi u Europskoj uniji od 25. travnja 2017.
English: Credelio is available as chewable tablets in seven different strengths (the lowest two strengths for cats, the rest for dogs) which are given to the animals with food or within 30 minutes after feeding.
Croatian: Credelio je dostupan u tabletama koje se žvaču, u sedam različitih jačina (dvije najniže jačine za mačke, ostatak za pse), koje se životinjama daju s hranom ili u roku od 30 minuta nakon obroka.
English: Because ticks must start feeding on the animal in order to be killed by the medicine, the risk of transmission of diseases that they may carry cannot be excluded.
Croatian: Budući da se krpelji moraju početi hraniti krvlju životinje da bi ih se moglo iskorijeniti VMP-om, ne može se isključiti rizik od prijenosa bolesti koje oni mogu nositi.
English: Lotilaner kills these parasites that have ingested the blood by acting on their nervous system.
Croatian: Lotilaner ubija parazite koji su popili krv životinje tako što djeluje na njihov živčani sustav.
English: Why is Credelio authorised in the EU?
Croatian: Zašto je Credelio odobren u EU-u?
English: The European Medicines Agency decided that Credelio's benefits are greater than its risks and it can be authorised for use in the EU.
Croatian: Europska agencija za lijekove zaključila je da koristi od VMP-a Credelio nadmašuju s njim povezane rizike te da se može izdati odobrenje za njegovu primjenu u EU-u.
English: What is Credelio and what is it used for?
Croatian: Što je Credelio i za što se koristi?
English: Lotilaner kills fleas before they can lay eggs and so helps to reduce contamination of the animal's environment.
Croatian: Lotilaner ubija buhe prije nego što uspiju izleći jajašca te tako pomaže pri smanjivanju kontaminacije okruženja životinje.
English: An overview of Credelio and why it is authorised in the EU
Croatian: Pregled VMP-a Credelio i zašto je odobren u EU-u
English: The active substance in Credelio, lotilaner, acts as an ‘ectoparasiticide'.
Croatian: Djelatna tvar u VMP-u Credelio, lotilaner, djeluje kao „ektoparaziticid”.
English: It contains the active substance lotilaner.
Croatian: Sadrži djelatnu tvar lotilaner.
English: What are the risks associated with Credelio?
Croatian: Koji su rizici povezani s VMP-om Credelio?
English: Credelio can be used as part of the management of flea allergy dermatitis (an allergic reaction to flea bites).
Croatian: Credelio se može također koristiti kao dio strategije liječenja alergijskog dermatitisa uzrokovanog buhama (alergijske reakcije na ugrize buha).
English: Credelio is a veterinary medicine used to treat flea and tick infestations in dogs and cats.
Croatian: Credelio je veterinarsko-medicinski proizvod koji se koristi za liječenje infestacije pasa i mačaka buhama i krpeljima.
English: How does Credelio work?
Croatian: Kako djeluje Credelio?
English: How is Credelio used?
Croatian: Kako se Credelio koristi?