FrancophonIA/ELRC3.0 huggingface dataset:
English: Laboratoires Biove 3 rue de Lorraine 62510 Arques FRANCE
Slovenian: Francija Laboratoires Biove 3 rue de Lorraine 62510 Arques
English: 1093 Budapest HUNGARY
Slovenian: 1093 Budapest MADŽARSKA
English: In particular, information about the study conditions (medical history of the study site, housing and feeding conditions, light/dark cycle) as well as the treatment schedule (medication ad libitum for 24 hours/ pulse medication) was missing or very limited.
Slovenian: Večinoma so manjkale informacije o pogojih študije (medicinska anamneza na mestu študije, pogoji bivanja in krmljenja, ciklusi svetlobe/teme) ter urnik zdravljenja (zdravila ad libitum za 24 ur/pulzno zdravljenje) ali pa so bile te zelo omejene.
English: PARCELA409-410 25191 Lérida SPAIN
Slovenian: PARCELA409-410 25191 Lérida ŠPANIJA
English: List of the names, pharmaceutical forms, strengths of the veterinary medicinal products, animal species, route of administration, indications / withdrawal periods and applicants / marketing authorisation holders in the Member States
Slovenian: SEZNAM IMEN, FARMACEVTSKIH OBLIK, JAKOSTI ZDRAVILA ZA UPORABO V VETERINARSKI MEDICINI, ŽIVALSKIH VRST, POTI UPORABE, INDIKACIJ/KARENC IN PREDLAGATELJEV/IMETNIKOV DOVOLJENJA ZA PROMET Z ZDRAVILOM V DRŽAVAH ČLANICAH
English: mg/kg/day (pigs)
Slovenian: mg/kg/dan (prašiči)
English: However the publication does not provide sufficient information to calculate the actual dose intake of the study animals.
Slovenian: Vendar objava ne vsebuje dovolj informacij za izračun dejanskega vnosa odmerka pri proučevanih živalih.
English: 10 rue Clement Ader
Slovenian: Francija Noe 10 rue Clement Ader
English: Tierarzneimittel Gesellschaft m.b.H.Kaplanstraß e 10 AT
Slovenian: Avstrija Chevita Tierarzneimittel Gesellschaft m.b.H.Kaplanstraß e 10 AT
English: However, the publication did not include the necessary information to derive a daily actual dose intake of the study birds.
Slovenian: Vendar v objavo niso vključili informacij, potrebnih za izpeljavo dnevnega dejanskega vnesenega odmerka pri proučevanih pticah.
English: 47100 Forli ITALY
Slovenian: 47100 Forli ITALIJA
English: Via Augusta, 302 08017 Barcelona SPAIN
Slovenian: Via Augusta, 302 08017 Barcelona ŠPANIJA
English: As regards Pasteurella multocida infection, two experimental studies in broiler chickens were presented, i.e. one publication (Semjen et al., (1998)1, and one proprietary study.
Slovenian: V zvezi z okužbo s Pasteurella multocida sta bili predstavljeni dve eksperimentalni študiji pri pitovnih piščancih, tj. ena objava (Semjen et al., (1998))1 in ena lastniška študija.
English: As regards P. multocida infections, results of an experimental model study indicate a treatment dose of 10 mg/kg body weight for 4 or 5 days, but no confirmatory clinical data obtained under commercial conditions has been made available.
Slovenian: V zvezi z okužbami s P. multocida rezultati študije na poskusnih modelih kažejo terapevtski odmerek 10 mg/kg telesne mase 4 ali 5 dni, vendar potrditveni klinični podatki v komercialnih okoliščinah niso bili na voljo.
English: Barcelona, 411 08620 San Vicens del Horts SPAIN
Slovenian: Barcelona, 411 08620 San Vicens del Horts ŠPANIJA
English: At this dose levels mean plasma doxycycline levels of 3.6 µg/ml (measured on the 2nd treatment day were achieved.
Slovenian: Pri tej koncentraciji so povprečne ravni doksiciklina v plazmi 3,6 µg/ml (izmerjeno 2. dan zdravljenja).
English: Hungary Kon-Pharma GmbH.
Slovenian: Madžarska Kon-Pharma GmbH.
English: Hungary Phylaxia Pharma Zrt.
Slovenian: Madžarska Phylaxia Pharma Zrt.
English: Therefore, CVMP recommends that the product literature for all concerned products in this procedure should include appropriate prudent use statements in line with what is recommended in the CVMP Guideline on the SPC for antimicrobials (EMEA/CVMP/SAGAM/383441/2005)8 and information on correct administration.
Slovenian: CVMP zato priporoča, da literatura o vseh zdravilih, ki jih zadeva ta postopek, vsebuje ustrezne izjave o preudarni uporabi v skladu s priporočili Smernice CVMP o povzetku glavnih značilnosti protimikrobnih zdravil (EMEA/CVMP/SAGAM/383441/2005)8 in informacije o pravilni uporabi.
English: 71 08503 GURB - VIC SPAIN
Slovenian: 71 08503 GURB - VIC ŠPANIJA
English: Armazém nº 21 Casal do Bagulho Granja de Alpriate 2625-607 Vialonga PORTUGAL
Slovenian: Casal do Bagulho Granja de Alpriate 2625-607 Vialonga PORTUGALSKA
English: Alternatively, the concentrated solution can be used in a proportional water medicator.
Slovenian: Drugače se lahko koncentrirana raztopina uporabi v napravi za proporcionalno vmešavanje zdravil.
English: Romania s.c. romvac company s.a.Şos.
Slovenian: Romunija s.c. romvac company s.a.Şos.
English: Bucharest ROMANIA
Slovenian: Bucharest ROMUNIJA
English: The use of doxycycline hyclate for all claimed indications in chickens as well as the use of doxycycline hyclate in other poultry species was considered well-established.
Slovenian: Uporaba doksiciklinijevega hiklata za vse predlagane indikacije pri piščancih ter uporaba doksiciklinijevega hiklata pri drugih vrstah perutnine se šteje za dobro uveljavljeno.
English: The daily doses administered to chickens ranged between 10.36 mg/kg body weight, 14.47 mg/kg body weight and 25 mg/kg body weight.
Slovenian: Dnevni odmerki, uporabljeni pri piščancih, so bili v razponu med 10,36 mg/kg telesne mase, 14,47 mg/kg telesne mase in 25 mg/kg telesne mase.
English: Zoovetvaru uusaru 5
Slovenian: Estonija Zoovetvaru uusaru 5
English: Pharmagal s.r.o., Murgašova 5, 949 01 Nitra, Slovak Republic
Slovenian: Pharmagal s.r.o., Murgašova 5, 949 01 Nitra, Slovaška
English: Different product formulations were used in the studies containing, doxycycline hyclate/hydrochloride at different concentrations; almost all included acidifiers in the formulation (usually citric acid).
Slovenian: V študijah so bile uporabljene različne formulacije zdravil, ki so vsebovale doksiciklinijev hiklat/doksiciklinijev hidroklorid v različnih koncentracijah; v skoraj vseh so bila vključena sredstva za zakisanje (po navadi citronska kislina).
English: Via W. Tobagi n.7 20068 Peschiera Borromeo (Milano) ITALY
Slovenian: Via W. Tobagi n.7 20068 Peschiera Borromeo (Milano) ITALIJA
English: The study published by Goren et al. (1988)3 was designed as a dose titration study with doxycycline administered at dosages of 25-1000 ppm in drinking water for 5 consecutive days.
Slovenian: Študija, ki so jo objavili Goren et al. (1988)3, je bila zasnovana kot študija titracije odmerka, v kateri so doksiciklin dajali 5 zaporednih dni v pitno vodo v razponu odmerkov 25-1 000 ppm.
English: In the proprietary study, diarrhoea was one of the main clinical symptoms observed in infected untreated animals, which is not considered typical for Pasteurellosis.
Slovenian: V lastniški študiji je bila eden od glavnih kliničnih simptomov, ki so jih spremljali pri okuženih nezdravljenih živalih, driska, ki pa se ne šteje kot značilen simptom za pasteurelozo.
English: Czech republic
Slovenian: Češka republika
English: However there was no documented evidence for lack of efficacy in the treatment of respiratory infection associated with Mycoplasma gallisepticum with any other of the approved dosage regimens (10-25 mg/kg body weight).
Slovenian: Ni pa dokumentiranih dokazov o neučinkovitosti pri zdravljenju okužb dihal z Mycoplasma gallisepticum pri nobenem od odobrenih režimov odmerjanja (10-25 mg/kg telesne mase)
English: DOXYVIT 40% per 3-6 L of drinking water
Slovenian: DOXYVIT 40 % na 3-6 l pitne vode
English: One of these studies serve as the confirmatory evidence for the efficacy of this target dose, based on objective parameters such as a significant reduction of the percentage of animals with pathological lesions and total lesion scores typical of the disease and significant reduction in the recovery rate of M. gallisepticum after treatment.
Slovenian: Ena od teh študij velja kot potrditveni dokaz za učinkovitost tega ciljnega odmerka na podlagi objektivnih parametrov, kot so bistveno zmanjšanja odstotka živali s patološkimi lezijami in skupnim točkovanjem lezij, ki je značilno za bolezen, ter bistveno zmanjšanje stopnje izolacije M. gallisepticum po zdravljenju.
English: Comparison of these infection studies that investigate Colibacillosis was problematic due to considerable differences in the experimental conditions such as the use of different challenge strains and infectious dose levels, different time of treatment initiation, and differences in the chickens (age, weight, and breed) used.
Slovenian: Primerjava omenjenih študij okužb, v katerih so raziskovali kolibacilozo, je težavna zaradi bistvenih razlik v eksperimentalnih pogojih, kot je uporaba različnih izzivnih sevov in ravni infektivnega odmerka, različnih časov uvedbe zdravljenja in razlik v uporabljenih piščancih (starost, masa, pasma).
English: The United Kingdom expressed concerns that differences in the posology, dose range, duration of treatment and withdrawal periods established across the European Union for all strengths of water soluble powders and oral solutions containing doxycycline hyclate indicated for use in poultry and intended for administration via drinking water may present a potential serious risk to both animal health and human health, and requested the CVMP to give its opinion on the matter.
Slovenian: Združeno kraljestvo je izrazilo zadržek, da lahko razlike v odmerjanju, razponih odmerkov, trajanju zdravljenja in karencah, ki veljajo v Evropski uniji za vse jakosti vodotopnih praškov in peroralnih raztopin, ki vsebujejo doksiciklinijev hiklat in so indicirani za uporabo pri perutnini ter za dajanje s pitno vodo, pomenijo možno resno tveganje za zdravje živali in ljudi, zato je zaprosilo CVMP, da poda mnenje glede te zadeve.
English: Via Colleoni n.15 20041 Agrate Brianza (Milano) ITALY
Slovenian: Via Colleoni n.15 20041 Agrate Brianza (Milano) ITALIJA
English: While the data submitted by Applicants/Marketing Authorisation Holders failed to provide sufficient documented evidence to support the established doses for all other indications and species, there was, however, no new information indicating any new risk associated with the use of doxycycline in poultry in relation to lack of efficacy.
Slovenian: Čeprav podatki, ki so jih predložili predlagatelji/imetniki dovoljenja za promet z zdravilom, niso vsebovali dovolj dokazov v podporo uveljavljenim odmerkom za vse druge indikacije in živalske vrste, ni novih informacij, ki bi kazale novo tveganje, povezano z uporabo doksiciklina pri perutnini v zvezi z neučinkovitostjo.
English: 5530 AD Bladel THE
Slovenian: 5530 AD Bladel NIZOZEMSKA
English: Sogeval Laboratoires 200 route De Mayenne 53 022 Laval Cedex FRANCE
Slovenian: Laboratoires 200 route De Mayenne 53 022 Laval Cedex FRANCIJA
English: S.A. Pol. Ind. La Borda c/Mas Pujades 11-12
Slovenian: La Borda c/Mas Pujades 11-12
English: A high resistance rate of E. coli, isolated from chickens, against tetracyclines has been documented.
Slovenian: Ugotovljena je visoka stopnja odpornosti E. coli, izolirane iz piščancev, proti tetraciklinom.
English: All tetracyclines have a broad spectrum of activity which include Gram-positive and Gram-negative bacteria, chlamydias, rickettsias, mycoplasmas and spirochaetes.
Slovenian: Vsi tetraciklini imajo širok spekter aktivnosti, ki vključujejo grampozitivne in gramnegativne bakterije, klamidije, rikecije, mikoplazme in spirohete.
English: BOX 205
Slovenian: P.O. BOX 205
English: Romania S.C. Crida pharm s.r.l
Slovenian: Romunija S.C. Crida pharm s.r.l
English: The data submitted for Chlamydiosis were inconclusive and therefore there was insufficient information to support this indication both in chickens and other target species for the currently approved products that are within the scope of this referral procedure.
Slovenian: Podatki, predloženi za klamidiozo, so bili neprepričljivi, zato je bilo premalo informacij v podporo tej indikaciji pri piščancih in drugih ciljnih živalskih vrstah za trenutno odobrena zdravila, ki so zajeta v obseg tega napotitvenega postopka.
English: With regard to the E. coli infections in poultry the data submitted was not sufficient.
Slovenian: Podatki, predloženi v zvezi z okužbami z E. coli pri perutnini, so bili nezadostni.
English: = .... mg [product name] per l drinking water
Slovenian: = .... mg zdravila [ime zdravila] na l pitne vode
English: As eradication of the target pathogens may not be achieved, medication should therefore be combined with good management practices, e.g. good hygiene, proper ventilation, no overstocking.
Slovenian: Ker izkoreninjenja ciljnih bolezenskih povzročiteljev morda ni možno doseči, je treba zdravilo kombinirati z dobro prakso obvladovanja bolezni, npr. ustrezno higieno, ustreznim prezračevanjem, preprečevanjem naselitve prevelikega števila živali na enoto.
English: Antimicrobial efficacy as evident from recovery rate of O. rhinotracheale was not confirmed.
Slovenian: Protimikrobna učinkovitost, ki so jo dokazovali s stopnjo izolacije O. rhinotracheale, ni bila potrjena.
English: Scientific conclusions and grounds for amendment of the summary of product characteristics
Slovenian: ZNANSTVENI ZAKLJUČKI IN PODLAGA ZA DOPOLNILO POVZETKA GLAVNIH ZNAČILNOSTI ZDRAVILA
English: Meat - 4 days
Slovenian: meso - 4 dni
English: Doxycycline was also shown to be superior to chlortetracycline used as positive control.
Slovenian: Dokazali so, da je doksiciklin boljši od klortetraciklina, ki se je uporabil kot pozitivna kontrola.
English: 4600 Wels AUSTRIA
Slovenian: 4600 Wels
English: CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7ª Edificio Trade 08028 Barcelona SPAIN
Slovenian: CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7ª Edificio Trade 08028 Barcelona ŠPANIJA
English: In order to obtain the correct dosage, the concentration in drinking water may have to be adjusted.
Slovenian: Koncentracijo v pitni vodi bo morda treba prilagoditi tako, da se doseže pravilni odmerek.
English: Romania PHYLAXIA PHARMA LTD
Slovenian: Romunija PHYLAXIA PHARMA LTD
English: Nevertheless as P. multocida was shown to be susceptible to doxycycline with a MIC90 up to 2µg/ml and covered by pharmacokinetic/pharmacodynamic analysis, the inclusion of P. multocida infections in the indication for chickens appears justified.
Slovenian: Ker pa je bilo dokazano, da je P. multocida občutljiva za doksiciklin z MIK 90 do 2 µg/ml in je bila zajeta v farmakokinetično/farmakodinamično analizo, se zdi vključitev okužb s P. multocida v indikacije za piščance utemeljena.
English: CEVA Saúde Animal -Produtos farmacêuticos e Imunológicos Lda.
Slovenian: Portugalska CEVA Saúde Animal -Produtos farmacêuticos e Imunológicos
English: From the overall data submitted by the Applicants/Marketing Authorisation Holders only nineteen responses were with full dossiers developed in accordance with the Article 12(3) of Directive 2001/82/EC.
Slovenian: Od vseh podatkov, ki so jih predložili predlagatelji/imetniki dovoljenj za promet z zdravili, je devetnajst odgovorov vsebovalo popolno dokumentacijo, ki je bila pripravljena v skladu členom 12(3) Direktive 2001/82/ES.
English: Amendments to be included in the relevant sections of the labelling
Slovenian: DOPOLNILA, KI SE VKLJUČIJO V USTREZNA POGLAVJA OZNAČEVANJA
English: Therefore, the inclusion of appropriate standard prudent use statements in line with recommendations of the CVMP guideline on the SPC of Antimicrobials and information on correct administration of the products concerned in this referral procedure was considered appropriate; the CVMP has recommended the variation of the Marketing Authorisations and amendments of the relevant sections of the Summary of Product Characteristics, labelling and package leaflet to include as a minimum the information set out in Annex III for the water soluble powders and oral solutions containing doxycycline hyclate indicated for use in poultry and intended for administration via drinking as referred in Annex I of the Opinion.
Slovenian: Zato se zdi primerno, da se vključijo ustrezne standardne izjave o preudarni rabi v skladu s priporočili Smernic CVMP o povzetku glavnih značilnosti protimikrobnih zdravil in podatkov o pravilni uporabi zdravil, ki jih zadeva ta postopek; je CVMP priporočil spremembo dovoljenj za promet z zdravilom in dopolnitev ustreznih poglavij povzetka glavnih značilnosti zdravila, označevanja in navodila za uporabo, da se vključijo vsaj tiste informacije, določene v Dodatku III za vodotopne praške in peroralne raztopine, ki vsebujejo doksiciklinijev hiklat in so indicirani za uporabo pri perutnini ter dajanju v pitno vodo, kakor je navedeno v Dodatku I mnenja.
English: It could be argued that doxycycline can be effectively used in the treatment of E. coli infections in broilers provided, however, that susceptibility to doxycycline is confirmed before initiation of treatment.
Slovenian: Obstajajo utemeljitve, da se lahko doksiciklin učinkovito uporablja za zdravljenje okužb z E. coli pri pitovnih piščancih, vendar je treba pred uvedbo zdravljenja preveriti občutljivost za doksiciklin.
English: The residue depletion studies presented by the MAHs indicated that the statistical approach6 as recommended by the Committee was used for the establishment of withdrawal periods whenever possible.
Slovenian: V študijah o izločanju ostankov, ki so jih predložili imetniki dovoljenj za promet z zdravili, so za določitev karenc - kadar je bilo možno - uporabili statistični pristop6 , kar priporoča Odbor.
English: Advice on correct administration
Slovenian: NASVET O PRAVILNI UPORABI ZDRAVILA
English: Special warning(s)
Slovenian: POSEBNO(A) OPOZORILO(A)
English: In the confirmatory phase, both the clinical and pathological response to artificial O. rhinotracheale infection was low in un-medicated controls.
Slovenian: V potrditveni fazi je bil klinični in patološki odziv na umetno okužbo z O. rhinotracheale pri nezdravljenih živalih majhen.
English: In an experimental setting testing homeopathic medication in the treatment of Colibacillosis in broiler chickens, doxycycline was used for control (Velkers et al., 2005)4.
Slovenian: V eksperimentalnem okolju so preverjali homeopatsko zdravilo za zdravljenje kolibaciloze pri pitovnih piščancih, za kontrolo pa so uporabili doksiciklin (Velkers et al., 2005)4.
English: 42010 Rio Saliceto (Reggio Emilia) ITALY
Slovenian: 42010 Rio Saliceto (Reggio Emilia) ITALIJA
English: However, data of the pilot phase indicate that chickens at the highest infectious dose level, treated with doxycycline at a dose of 20 mg/kg per day for 4 days showed a significant reduction in air sac lesions compared to un-medicated controls.
Slovenian: Vendar podatki iz pilotske faze kažejo, da so piščanci, ki so prejeli največji infektivni odmerek in so bili zdravljeni z odmerkom doksiciklina v višini 20 mg/kg dnevno 4 dni, izkazali pomembno zmanjšanje lezij zračnih vreč v primerjavi z živalmi, ki niso prejele zdravila.
English: Ornithrobacterium rhinotracheale infection.
Slovenian: Ornithrobacterium rhinotracheale
English: Gran Via Carlos III, 98 7ª Edificio Trade 08028 Barcelona SPAIN
Slovenian: Gran Via Carlos III, 98 7ª Edificio Trade 08028 Barcelona ŠPANIJA
English: 4-7 days with drinking water
Slovenian: 4-5 dni s pitno vodo
English: Hungary CENAVISA, S.A. Camí Pedra Estela S/N
Slovenian: Madžarska CENAVISA, S.A. Camí Pedra Estela S/N
English: INN Strength Pharmaceutical form
Slovenian: Jakost Farmacevt ska oblika
English: Slovenia Novartis Veterina d.o.o.
Slovenian: Slovenija Novartis Veterina d.o.o.
English: Two residue studies were in turkeys.
Slovenian: Dve študiji ostankov sta bili izvedeni pri puranih.
English: Hungary Industria Italiana Integratori TREI S.p.A.
Slovenian: Madžarska Industria Italiana Integratori TREI S.p.A.
English: Notwithstanding the fact that no clinical field study was presented to confirm the results obtained under experimental conditions, the use of doxycycline for the treatment of respiratory infections associated with P. multocida appears justified considering the good susceptibility of this pathogen to doxycycline (MIC90 up to 2µg/ml).
Slovenian: Čeprav za potrditev rezultatov, dobljenih v eksperimentalnih pogojih, ni bila predstavljena klinična terenska študija, izgleda, da je uporaba doksiciklina za zdravljenje okužb dihal, povezanih s P. multocida, utemeljena, če upoštevamo dobro občutljivost tega bolezenskega povzročitelja za doksiciklin (MIK 90 do 2 µg/ml).
English: Indications: For the prevention and treatment of several bacterial infections.
Slovenian: indikacije: za preprečevanje in zdravljenje različnih bakterijskih okužb
English: Via Togliatti n.5 42016 Guastalla (Reggio Emilia) ITALY
Slovenian: Via Togliatti n.5 42016 Guastalla (Reggio Emilia) ITALIJA
English: INDUSTRIA ITAILIANA INTEGRATORI TREI SpA Via Affarosa n.4 42010 Rio Saliceto (Reggio Emilia) ITALY
Slovenian: INDUSTRIA ITAILIANA INTEGRATORI TREI SpA Via Affarosa n.4 42010 Rio Saliceto (Reggio Emilia) ITALIJA
English: United kingdom
Slovenian: Združeno kraljestvo
English: Estonia
Slovenian: ESTONIJA
English: CVMP revised guideline on the SPC for antimicrobial products (EMEA/CVMP/SAGAM/383441/2005)http://www.ema.europa.eu/pdfs/vet/sagam/38344105enfin.pdf
Slovenian: Chemotherapy 63, 733-744, 2009 Popravljena smernica CVMP o povzetku glavnih značilnosti protimikrobnih zdravil (EMEA/CVMP/SAGAM/383441/2005) - http://www.ema.europa.eu/pdfs/vet/sagam/38344105enfin.pdf
English: In the submitted Periodic Safety Update Reports for the concerned products no lack of efficacy has been reported for any of the claimed indications in any of the target species.
Slovenian: V predloženih rednih posodobljenih poročilih o varnosti zadevnih zdravil niso poročali o neučinkovitost za predlagane indikacije pri ciljnih živalskih vrstah.
English: As regards Ornithobacterium rhinotracheale infections, one GCP compliant controlled confirmatory efficacy study in chickens experimentally infected with O. rhinotracheale was presented.
Slovenian: V zvezi z okužbami z Ornithobacterium rhinotracheale je bila predložena ena kontrolirana potrditvena študija učinkovitosti (skladna z dobro klinično prakso) na piščancih, ki so bili eksperimentalno okuženi z O. rhinotracheale.
English: Huvepharma, Uitbreidingstraat
Slovenian: Nizozemska Huvepharma, Uitbreidingstraat
English: Both studies indicate that doxycycline at a daily dose of 10 mg/kg bw for 4 (5) consecutive days was effective in the treatment of induced acute fowl cholera as evidenced by the significant reduction of the mortality rate and pathological lesions characteristic for the disease as well as the recovery rate of the challenge strain, compared to infected unmedicated controls.
Slovenian: Obe študiji kažeta, da je bil doksiciklin v dnevnem odmerku 10 mg/kg TM za 4 (5) zaporednih dni učinkovit za zdravljenje inducirane akutne kolere perutnine, kar dokazuje pomembno zmanjšanje stopnje smrtnosti, patoloških lezij, ki so značilne za bolezen, ter stopnje izolacije izzivnega seva v primerjavi z okuženimi kontrolnimi živalmi, ki niso prejele zdravila.
English: Barcelona SPAIN
Slovenian: Barcelona ŠPANIJA
English: As evident from pharmacodynamic data, E. coli strains showed a very variable susceptibility against doxycycline with MIC90 values of 2 - 32µg/ ml.
Slovenian: Kot je razvidno iz farmakodinamičnih podatkov, so imeli sevi E. coli zelo različno občutljivost za doksiciklin, saj so bile vrednosti MIK 90 v razponu 2-32 µg/ml.
English: INDUSTRIAL VETERINARIA S.A. Esmeralda, 19 - 4º 08950 ESPLUGUES DE LLOBREGAT SPAIN
Slovenian: INDUSTRIAL VETERINARIA S.A. Esmeralda, 19 - 4º 08950 ESPLUGUES DE LLOBREGAT ŠPANIJA
English: As no need for revision of the dose was identified consequently the withdrawal periods of the products concerned do not need revision.
Slovenian: Ker ni bila ugotovljena potreba po spremembi odmerka, karenc za zadevna zdravila ni treba spreminjati.
English: Due to variability (time, geographical) in susceptibility of bacteria for doxycycline, bacteriological sampling and susceptibility testing of micro-organisms from diseased birds on farm are highly recommended.
Slovenian: Zaradi razlik (časovnih, geografskih) med občutljivostjo bakterij za doksiciklin je zelo priporočljiv odvzem vzorca za bakteriologijo in določanje občutljivosti mikroorganizmov iz bolnih ptic na kmetiji.