FrancophonIA/ELRC3.0 huggingface dataset:
English: For young infants the contents may be mixed with infant formula, expressed breast milk or fruit puree and for infants and children under 6 years, mixed with soft food such as mashed potatoes or apple puree.immediately.
Danish: Til spædbørn kan indholdet blandes med modermælkserstatning, udmalket modermælk eller frugtmos, og til børn under seks år straks blandes i f.eks. kartoffelmos eller æblemos.
English: The rationale for cholic acid therapy is improvement of bile flow and fat absorption and restoration of a physiologic feedback inhibition on bile acid synthesis, lowering the production of toxic bile acid precursors.
Danish: Rationalet for behandling med cholsyre er at forbedre galdeflow og fedtabsorption og genoprette den fysiologiske feedbackhæmning af galdesyresyntesen og således sænke produktionen af toksiske galdesyreprækursorer.
English: Titanium dioxide (E171)
Danish: Titaniumdioxid (E171) Printerblæk
English: After administration of cholic acid a down-regulation of bile acid synthesis occurs and there is a strong decrease or almost complete disappearance of abnormal bile acids.
Danish: Efter administration af cholsyre nedreguleres galdesyresyntesen, og de abnorme galdesyrer bliver stærkt reduceret eller forsvinder næsten helt.
English: Patients with hepatic impairment who are treated with cholic acid should be monitored closely (see section 4.4).
Danish: Patienter, der er i behandling med cholsyre og har nedsat leverfunktion, bør overvåges tæt (se pkt.
English: For infants and children who cannot swallow capsules, the capsules may be opened and the content added to infant formula or juice.
Danish: Til spædbørn og børn, som ikke kan synke kapsler, kan kapslerne åbnes, og indholdet opblandes i modermælkserstatning eller juice.
English: • feeling of pins and needles (mild peripheral neuropathy)
Danish: • stikken og prikken (let perifer neuropati)
English: Serum transaminases were below the ULN for 1 patient and elevated (≥2 times the ULN) for 2 patients at baseline, were elevated for 2 patients in the worst post baseline analysis but were below the ULN for all 3 patients in the best post-treatment analysis.
Danish: Serumtransaminaser var under ULN hos 1 patient, og forhøjet (≥2 gange ULN) hos 2 patienter ved baseline, forhøjet hos 2 patienter i analysen med dårligste værdi efter baseline, men under ULN hos alle 3 patienter i analysen med bedste værdi efter behandling.
English: PHARMACEUTICAL FORM AND CONTENTS Hard capsule.
Danish: LÆGEMIDDELFORM OG INDHOLD (PAKNINGSSTØRRELSE) Kapsler, hårde.
English: MARKETING AUTHORISATION NUMBER EU/1/13/895/002
Danish: MARKEDSFØRINGSTILLADELSESNUMMER EU/1/13/895/002
English: Familial hypertriglyceridaemia
Danish: Familiær hypertriglyceridæmi
English: Conjugated cholic acid is absorbed in the ileum via transporters , passed back to the liver and enters another cycle of enterohepatic circulation.
Danish: Den konjugerede cholsyre absorberes fra ileum via transportproteiner, føres tilbage til leveren og gennemløber en ny cyklus i det enterohepatiske kredsløb.
English: Medicines for lowering cholesterol levels in the blood, such as cholestyramine, colestipol or colesevelam, and certain antacids which contain aluminium (e.g. indigestion relief products) may affect the absorption of cholic acid.
Danish: Kolesterolsænkende lægemidler såsom colestyramin, colestipol eller colesevelam kan påvirke optagelsen af cholsyre, hvilket ligeledes gælder visse aluminiumholdige syreneutraliserende midler (f.eks. midler mod fordøjelsesbesvær).
English: Printing ink
Danish: Printerblæk
English: Kolbam contains a substance called cholic acid.
Danish: Kolbam indeholder det aktive stof cholsyre.
English: Patients with familial hypertriglyceridaemia
Danish: Patienter med familiær hypertriglyceridæmi
English: Diarrhoea is also known to occur in cases of excessive dosing with cholic acid.
Danish: Diarré vides at forekomme ved overdosering med cholsyre.
English: CONTENTS OF THE PACK AND OTHER INFORMATION What Kolbam contains - The active substance is cholic acid.
Danish: Kolbam indeholder: Det aktive stof er cholsyre.
English: • yellowing of the skin (jaundice)
Danish: • gulfarvning af huden (ikterus)
English: Cholic acid can be used during breastfeeding if the doctor considers that the benefits to the patient outweigh the possible risk.
Danish: Det kan overvejes at anvende cholsyre under amning, hvis lægen finder, at fordelene for patienten overstiger den mulige risiko.
English: The 50 mg capsules are orange (black imprint “ASK001” and “50mg”).
Danish: 50 mg kapslerne er orange (sort aftryk "ASK001" og "50 mg").
English: A total of 53 patients took part in the clinical study and received at least one dose of cholic acid; 22 (42%) were treatment naive, i.e., received their first dose of cholic acid during study CAC002-01.
Danish: Heraf var 22 (42 %) behandlingsnaive, dvs. de fik deres første dosis cholsyre i undersøgelse CAC-002-01.
English: If you take more Kolbam than you should
Danish: Hvis du har taget for meget Kolbam
English: DD month YYYY
Danish: <{DD måned ÅÅÅÅ}>
English: The adverse reactions reported in the literature with an unknown frequency are also reported in the following table.
Danish: Tabellen indeholder desuden bivirkninger, der beskrives i litteraturen, og hvis hyppighed ikke er kendt:
English: Kolbam is used to treat these ‘inborn errors of bile acid synthesis'.
Danish: Kolbam anvendes til behandling af disse medfødte fejl i galdesyresyntesen.
English: Titanium dioxide (E171) Red iron oxide (E172)
Danish: Titaniumdioxid (E171) Jernoxid, rød (E172)
English: MARKETING AUTHORISATION NUMBER EU/1/13/895/001
Danish: MARKEDSFØRINGSTILLADELSESNUMMER) EU/1/13/895/001
English: The cholic acid dose for patients with familial hypertriglyceridaemia will have to be established and adjusted as necessary: an elevated dose may be required in order to suppress urinary bile acids (see section 4.4).
Danish: Til patienter med familiær hypertriglyceridæmi skal dosis af cholsyre fastlægges og om nødvendigt tilpasses, idet dosisforhøjelse kan være nødvendig for at undertrykke galdesyrer i urinen (se pkt.
English: Patients with newly diagnosed, or a family history of, familial hypertriglyceridaemia may have poor absorption of cholic acid from the intestine.
Danish: Patienter med nydiagnosticeret hypertriglyceridæmi eller med familiær hypertriglyceridæmi kan have nedsat cholsyreabsorption fra tarmen.
English: • oestrogen,
Danish: • østrogen
English: - If you get any side effects, talk to your doctor, pharmacist or nurse.
Danish: - Hvis du får bivirkninger, skal du sige det til lægen eller på apoteket eller til sundhedspersonalet.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each hard capsule contains 250 mg of cholic acid.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hver hård kapsel indeholder 250 mg cholsyre.
English: If administration of ciclosporin is considered necessary, serum and urinary bile acid levels should be closely monitored and the cholic acid dose adjusted accordingly.
Danish: Hvis administration af ciclosporin anses for nødvendig, bør galdesyreindholdet overvåges tæt, og dosis af cholsyre justeres i henhold hertil.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each hard capsule contains 50 mg of cholic acid.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hver hård kapsel indeholder 50 mg cholsyre.
English: This leaflet was last revised in DDmonthYYYY.
Danish: Denne indlægsseddel blev senest revideret DDmÅÅÅÅ.
English: Marketing Authorisation Holder Retrophin Europe Limited Palmerston House Fenian Street
Danish: Indehaver af markedsføringstilladelsen Retrophin Europe Limited Palmerston House, Fenian Street Dublin 2
English: Kolbam 250 mg: Each capsule contains 250 mg of cholic acid.
Danish: Kolbam, 250 mg: Hver kapsel indeholder 250 mg cholsyre.
English: The registry will monitor accumulating data on efficacy and safety in the treatment of inborn errors in primary bile acid synthesis in infants, children, adolescents and adults due to Sterol 27-hydroxylase (presenting as cerebrotendinous xanthomatosis,
Danish: Registret skal overvåge akkumulerende data om sikkerheden og virkningen til behandling af medfødte fejl i galdesyresyntesen hos spædbørn, børn, unge og voksne som følge af sterol 27-hydroxylase (manifesteret som cerebrotendinøs xanthomatose, CTX), 2- (eller α-) methylacyl-CoA racemase (AMACR) og kolesterol 7α-hydroxylase (CYP7A1) mangel.
English: Once absorbed, exogenous cholic acid will enter into the body's bile acid pool and will undergo multiple cycles of enterohepatic circulation.
Danish: Eksogen cholsyre vil efter absorption indgå i kroppens pool af galdesyrer og gennemløbe en række cyklusser i det enterohepatiske kredsløb.
English: Kolbam 50 mg: Each capsule contains 50 mg of cholic acid.
Danish: Kolbam, 50 mg: Hver kapsel indeholder 50 mg cholsyre.
English: The 250 mg capsules are white (black imprint “ASK002” and “250mg”).
Danish: 250 mg kapslerne er hvide (sort aftryk "ASK002" og "250 mg").
English: Propylene Glycol (E1520) Strong Ammonia Solution (E527) Potassium Hydroxide (E525) Black Iron Oxide (E172)
Danish: Propylenglycol (E1520) Salmiakspiritus (E527) Kaliumhydroxid (E525) Sort jernoxid (E172)
English: The cholic acid dose for patients with familial triglyceridaemia will have to be established and adjusted as necessary (see section 4.2).
Danish: Ved familiær hypertriglyceridæmi skal dosis af cholsyre fastlægges og tilpasses efter behov (se pkt.
English: Urinary bile acids were normal for all patients (100%) at baseline and worst post-baseline assessments, and for most patients (88%) at the best post-baseline assessment; 1 patient (12%) had a slight elevation of urinary bile acids at best post-baseline assessment.
Danish: Niveauet af galdesyrer i urinen var normalt hos alle patienter (100 %) ved baseline og ved dårligste vurderinger efter baseline, og hos de fleste patienter (88 %) ved den bedste vurdering efter baseline.
English: The study was an open-label, single arm, non-randomized design.
Danish: Undersøgelsen var åben og urandomiseret og havde én forsøgsarm.
English: • skin lesions
Danish: • hudforandringer
English: Hepatic impairment
Danish: • let kvalme
English: The safety and efficacy of cholic acid in neonates less than one month of age has not been established.
Danish: Pædiatrisk population cholsyre sikkerhed og virkning hos nyfødte børn (under 1 måned) er ikke klarlagt.
English: The use of cholic acid may be considered during pregnancy if your doctor considers that the benefits to you outweigh any possible risk.
Danish: Hvis du er gravid, kan det overvejes at anvende cholsyre, hvis lægen finder, at fordelene for dig overstiger den mulige risiko.
English: Kolbam 50 mg hard capsules Kolbam 250 mg hard capsules cholic acid
Danish: Kolbam, hårde kapsler, 50 mg Kolbam, hårde kapsler, 250 mg cholsyre
English: 250 mg Capsule shell Gelatin
Danish: 250 mg kapsel
English: Patients with certain types of conditions known as inborn errors of bile synthesis cannot produce cholic acid and bile normally, which leads to the production and build-up of abnormal substances that are potentially damaging to the liver.
Danish: Patienter med sygdomme med medfødte fejl i galdesyntesen kan ikke danne cholsyre og galde på normal måde.
English: 250 mg capsule: Size number 0 capsule with a white cap (black imprint “ASK002”) and white body (black imprint “250mg”).
Danish: 250 mg kapsel: Kapselstørrelse 0 med hvid overdel og hvid underdel (sort aftryk "ASK002" og "250 mg").
English: • heartburn (gastric reflux)
Danish: • halsbrand (ved tilbageløb fra mavesækken)
English: NAME OF THE MEDICINAL PRODUCT Kolbam 250 mg hard capsules.
Danish: LÆGEMIDLETS NAVN Kolbam, hårde kapsler, 250 mg.
English: Adverse reactions in patients (both adults and children) receiving cholic acid are generally mild to moderate in severity; the main reactions observed are given in the table below.
Danish: Behandling med cholsyre medfører sædvanligvis kun lette til moderate bivirkninger hos både voksne og børn; nedenstående tabel angiver de vigtigste iagttagne bivirkninger.
English: NAME OF THE MEDICINAL PRODUCT Kolbam 50 mg hard capsules.
Danish: LÆGEMIDLETS NAVN Kolbam, hårde kapsler, 50 mg.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each capsule contains 250 mg cholic acid
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver kapsel indeholder 250 mg cholsyre
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each capsule contains 50 mg cholic acid
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver kapsel indeholder 50 mg cholsyre
English: 50 mg capsule: Size number 2 capsule with a Swedish orange cap (black imprint “ASK001”) and body (black imprint “50mg”).
Danish: 50 mg kapsel: Kapselstørrelse 2 med orange overdel og underdel (sort aftryk "ASK001" og "50 mg").
English: Printing ink Shellac (E904) Propylene Glycol (E1520) Strong Ammonia Solution (E527) Potassium Hydroxide (E525) Black Iron Oxide (E172) What Kolbam looks like and contents of the pack Kolbam is provided as hard capsules.
Danish: Printerblæk - Shellac (E904) - Propylenglycol (E1520) - Salmiakspiritus (E527) - Kaliumhydroxid (E525) - Sort jernoxid (E172)
English: Treatment should be stopped earlier if there are clear indicators of severe hepatic failure.
Danish: Ved klare tegn på svært leversvigt bør behandlingen seponeres tidligere.
English: Based on clinical trial data, adverse reactions in patients (both adults and children) receiving cholic acid are generally mild to moderate in severity and are provided in the following table.
Danish: Cholsyre har sædvanligvis kun lette til moderate bivirkninger hos både voksne og børn, som det fremgår af følgende tabel, der bygger på de kliniske undersøgelser.
English: You should check with your doctor or pharmacist if you are unsure.
Danish: - Spørg lægen, apotekspersonalet eller sundhedspersonalet, hvis der er mere, du vil vide.
English: Malaise
Danish: Hyppighed
English: Posology
Danish: MedDRA
English: NAME OF THE MEDICINAL PRODUCT Kolbam 50 mg hard capsules cholic acid
Danish: Kolbam, hårde kapsler, 50 mg cholsyre
English: NAME OF THE MEDICINAL PRODUCT Kolbam 250 mg hard capsules cholic acid
Danish: Kolbam, hårde kapsler, 250 mg cholsyre
English: Breastfeeding
Danish: Dosering
English: Packaging Content (concentration)
Danish: Emballage Indhold Pakningsstør relse
English: Route of administration
Danish: Indgivelse svej
English: This dose should not be increased.
Danish: Denne dosis må ikke øges.
English: Date of first authorisation: 04 March 2011 Date of latest renewal: 19 November 2015
Danish: Dato for første markedsføringstilladelse: 4. marts 2011 Dato for seneste fornyelse: 19. november 2015
English: Try to take your daily dose at about the same time each day.
Danish: Prøv at tage medicinen på nogenlunde samme tidspunkt hver dag.
English: Ifirmacombi should be taken at least one hour before or four hours after these medications;
Danish: Ifirmacombi bør tages mindst en time før eller fire timer efter disse lægemidler.
English: Primary aldosteronism:
Danish: Primær aldosteronisme:
English: Not known: tinnitus
Danish: Ikke kendt: tinnitus
English: and 5.1)
Danish: og 5.1).
English: See also information under the heading “Do not take Ifirmacombi”.
Danish: Se også information under overskriften ”Tag ikke Ifirmacombi”.
English: The maximal blood pressure lowering effect should be reached 6-8 weeks after beginning treatment.
Danish: Den maksimale blodtrykssænkende virkning nås 6-8 uger efter behandlingen er påbegyndt.
English: Children and adolescents Ifirmacombi should not be given to children and adolescents (under 18 years).
Danish: Børn og unge Ifirmacombi må ikke gives til børn og unge (under 18 år).
English: Additional information on irbesartan interactions:
Danish: Yderligere information om interaktioner med irbesartan:
English: Some of these effects may be serious and may require medical attention.
Danish: Nogle af bivirkningerne kan dog være alvorlige og kræve behandling.
English: While this is not documented with Ifirmacombi, a similar effect should be anticipated.
Danish: Selvom dette ikke er dokumenteret for Ifirmacombi, kan der forventes en lignende virkning.
English: After either oral or intravenous administration of
Danish: Efter enten oral eller intravenøs administration af
English: You can take Ifirmacombi with or without food.
Danish: Du kan tage Ifirmacombi med eller uden mad.
English: Non-steroidal anti-inflammatory drugs:
Danish: Non-steroide antiinflammatoriske lægemidler:
English: It is important that you continue to take Ifirmacombi until your doctor tells you otherwise.
Danish: Det er vigtigt, at du fortsætter med at tage Ifirmacombi, indtil lægen siger, du kan stoppe.
English: Chloride deficit is generally mild and usually does not require treatment.
Danish: Chloridmangel er generelt beskeden og kræver normalt ingen behandling.
English: Not known: fever
Danish: Ikke kendt: feber
English: In long-term follow-up studies, the effect of irbesartan/hydrochlorothiazide was maintained for over one year.
Danish: I langvarige opfølgningsstudier blev virkningen af irbesartan/hydrochlorthiazid opretholdt i mere end 1 år.
English: When clinically appropriate direct change from monotherapy to the fixed combinations may be considered:
Danish: Hvis det er klinisk hensigtsmæssigt, kan direkte skift fra monoterapi til de faste kombinationer overvejes:
English: Not known: postural hypotension
Danish: Ikke kendt: postural hypotension
English: Ifirmacombi with food, drink and alcohol Ifirmacombi can be taken with or without food.
Danish: Brug af Ifirmacombi sammen med mad, drikke og alkohol Ifirmacombi kan tages med eller uden mad.
English: The most common signs and symptoms of overdose are nausea and somnolence.
Danish: De almindelige tegn og symptomer på overdosering er kvalme og døsighed.
English: Ifirmacombi is not recommended for use in children and adolescents because the safety and efficacy have not been established.
Danish: Ifirmacombi frarådes til behandling af børn og unge, da sikkerhed og virkning ikke er klarlagt.
English: See section 2 "Ifirmacombi contains sodium".
Danish: Se punkt 2 ”Ifirmacombi indeholder natrium”.
English: The primary objective of this study was to compare the proportion of patients whose SeDBP was controlled (SeDBP < 90 mmHg) at Week 5 of treatment.
Danish: Det primære formål med forsøget var at sammenligne andelen af patienter, hvis SeDBT var kontrolleret (SeDBT < 90 mmHg) efter 5 ugers behandling.
English: Plasma protein binding of irbesartan is approximately 96%, with negligible binding to cellular blood components.
Danish: Irbesartans plasma-proteinbinding er ca. 96%, med en ubetydelig binding til cellulære blodkomponenter.
English: If Ifirmacombi is used during breast feeding, doses should be kept as low as possible.
Danish: Hvis Ifirmacombi anvendes i ammeperioden, bør dosis være så lav som muligt.
English: The frequency of adverse reactions listed below is defined using the following convention: - Very common (1/10) - Common (1/100 to <1/10) - Uncommon (1/1,000 to <1/100) - Rare (1/10,000 to <1/1,000) - Very rare (<1/10,000) - Not known (cannot be estimated from the available data)
Danish: Hyppigheden af bivirkninger anført nedenfor defineres i henhold til følgende konventioner: meget almindelig (≥ 1/10); almindelig (≥ 1/100 til < 1/10); ikke almindelig (≥ 1/1.000 til < 1/100); sjælden (≥ 1/10.000 til < 1/1.000); meget sjælden (< 1/10.000) ikke kendt (kan ikke estimeres ud fra forhåndenværende data)
English: Metabolic and endocrine effects:
Danish: Metabolisk og endokrin virkning:
English: Ifirmacombi has been rarely associated with symptomatic hypotension in hypertensive patients without other risk factors for hypotension.
Danish: Ifirmacombi er kun sjældent blevet associeret med symptomatisk hypotension hos hypertensive patienter uden andre risikofaktorer for hypotension.
English: If you forget to take Ifirmacombi
Danish: Hvis du har glemt at tage Ifirmacombi
English: Uncommon: sexual dysfunction, libido changes
Danish: Ikke almindelig: seksuel dysfunktion, ændret libido
English: Epidemiological studies have shown that long term treatment with hydrochlorothiazide reduces the risk of cardiovascular mortality and morbidity.
Danish: Epidemiologiske studier har vist, at langtidsbehandling med hydrochlorthiazid reducerer risikoen for kardiovaskulær mortalitet og morbiditet.
English: The major circulating metabolite is irbesartan glucuronide (approximately 6%).
Danish: Den vigtigste cirkulerende metabolit er glukuronidet af irbesartan (ca. 6%).
English: Renal artery stenosis - Renovascular hypertension:
Danish: Renal arteriestenose - renovaskulær hypertension:
English: Twelve percent (12%) of patients were diabetic, 34% were hyperlipidemic and the most frequent cardiovascular condition was stable angina pectoris in 3.5% of the participants.
Danish: 12% af patienterne var diabetikere, 34% var hyperlipidæmiske, og den hyppigste kardiovaskulære sygdom var stabil angina pectoris hos 3,5% af deltagerne.
English: There was no evidence of mutagenicity, clastogenicity or carcinogenicity.
Danish: Der var ingen tegn på mutagenicitet, klastogenicitet eller karcinogenecitet.
English: Angiotensin II Receptor Antagonists (AIIRAs):
Danish: Angiotensin II-receptorantagonister (AIIRAer):
English: You should discontinue Ifirmacombi treatment and seek medical attention.
Danish: Du skal stoppe behandlingen med Ifirmacombiog søge lægehjælp.
English: The potential toxicity of the irbesartan/hydrochlorothiazide combination after oral administration was evaluated in rats and macaques in studies lasting up to 6 months.
Danish: Potentiel toksicitet af irbesartan/hydrochlorthiazid-kombinationen efter oral administration blev undersøgt hos rotter og makakaber i studier af op til 6 måneders varighed.
English: Whilst there is no controlled epidemiological data on the risk with Angiotensin II Receptor Antagonists (AIIRAs), similar risks may exist for this class of drugs.
Danish: Der findes ingen kontrollerede epidemiologiske data vedrørende risikoen med angiotensin-II-receptorantagonister (AIIRA'ere), men lignende risici kan findes for denne lægemiddelgruppe.
English: When driving vehicles or operating machines, it should be taken into account that occasionally dizziness or weariness may occur during treatment of hypertension.
Danish: Ved bilkørsel eller betjening af maskiner skal der tages hensyn til, at der kan opstå svimmelhed eller træthed under behandling af hypertension.
English: jaundice hepatitis, abnormal liver function
Danish: Gulsot hepatitis, abnorm leverfunktion
English: Food does not affect the bioavailability of Ifirmacombi.
Danish: Fødeindtagelse påvirker ikke biotilgængeligheden af Ifirmacombi.
English: No specific information is available on the treatment of overdose with Ifirmacombi.
Danish: Der foreligger ikke specifikke oplysninger om behandling af overdosering med Ifirmacombi.
English: If any of these side effects causes you problems, talk to your doctor.
Danish: Hvis nogen af disse bivirkninger medfører problemer for dig, skal du kontakte lægen.
English: In addition increases in blood urea nitrogen (BUN) (2.3%), creatine kinase (1.7%) and creatinine (1.1%) were also commonly observed in the trials.
Danish: Desuden var øget blodurinstof (BUN) (2,3%), kreatinkinase (1,7%) og kreatinin (1,1%) også almindelige observationer i forsøgene.
English: Irbesartan is a potent, orally active, selective angiotensin-II receptor (AT1 subtype) antagonist.
Danish: Irbesartan er en potent, oral aktiv, selektiv angiotensin II-receptor (AT1 undergruppe) antagonist.
English: The types and incidences of adverse events reported for patients treated with the combination were similar to the adverse event profile for patients on monotherapy.
Danish: Typen og forekomsten af de bivirkninger, der er indberettet hos patienter, som har fået behandling med kombinationen, svarede til bivirkningsprofilen for patienter i enkeltstofbehandling.
English: Marked hypercalcaemia may be evidence of hidden hyperparathyroidism.
Danish: Markant hyperkalcæmi kan være tegn på skjult hyperparathyreoidisme.
English: C irbesartan, 80-85% of the circulating plasma radioactivity is attributable to unchanged irbesartan.
Danish: C irbesartan kan 80-85% af den cirkulerende radioaktivitet i plasma tilskrives uomdannet irbesartan.
English: Common: fatigue
Danish: Almindelig: træthed