FrancophonIA/ELRC3.0 huggingface dataset:
English: SUSTAIN 7 - Ozempic vs. dulaglutide both in combination with metformin In a 40-week, open-label trial, 1,201 patients on metformin were randomised 1:1:1:1 to once weekly Ozempic 0.5 mg, dulaglutide 0.75 mg , Ozempic 1 mg or dulaglutide 1.5 mg, respectively.
Slovenian: V 40-tedenskem odprtem preskušanju so 1.201 bolnika, ki je prejemal metformin, randomizirali v razmerju 1:1:1:1 na 0,5 mg zdravila Ozempic, 0,75 mg dulaglutida, 1 mg zdravila Ozempic oziroma
English: Each dose contains 1 mg of semaglutide in 0.74 ml.
Slovenian: En odmerek vsebuje 1 mg semaglutida v 0,74 ml.
English: Ozempic 0.5 mg solution for injection: Each pre-filled pen contains 1.5 ml of solution, delivering 4 doses of 0.5 mg.
Slovenian: Ozempic 0,5 mg raztopina za injiciranje: en napolnjen injekcijski peresnik vsebuje 1,5 ml raztopine in omogoča odmerjanje 4 odmerkov po 0,5 mg.
English: Always make sure that a drop appears at the needle tip before you use a new pen for the first time.
Slovenian: Preden prvič uporabite nov injekcijski peresnik, se vedno prepričajte, da se na konici igle pojavi kapljica.
English: You may see a drop of solution at the needle tip after injecting.
Slovenian: Po injiciranju boste na konici igle morda opazili kapljico raztopine.
English: HbA1c at baseline was 8.2%, 8.4% and 8.4% for Ozempic 0.5 mg, Ozempic 1 mg, and placebo, respectively.
Slovenian: Izhodiščno je bil HbA1c v skupini z 0,5 mg zdravila Ozempic 8,2 %, z 1 mg zdravila Ozempic 8,4 % in s placebom 8,4 %.
English: At week 30, the change in HbA1c was -1.6%, -1.5% and 0.1% for Ozempic 0.5 mg, Ozempic 1 mg, and placebo, respectively.
Slovenian: HbA1c v skupini z 0,5 mg zdravila Ozempic -1,6 %, z 1 mg zdravila Ozempic -1,5 % in s placebom
English: Caution should be exercised when using semaglutide in patients with diabetic retinopathy treated with insulin.
Slovenian: Pri bolnikih z diabetično retinopatijo, zdravljenih z insulinom, je treba semaglutid uporabljati previdno.
English: Similar exposure was achieved with subcutaneous administration of semaglutide in the abdomen, thigh, or upper arm. Absolute bioavailability of subcutaneous semaglutide was 89%.
Slovenian: Absolutna biološka uporabnost subkutanega semaglutida je bila 89 %.
English: Intent-to-Treat (ITT) Population (N) HbA1c (%)
Slovenian: HbA1c (%) Izhodišče (povprečje)
English: Patients (%) achieving HbA1c <7% 68 FPG (mmol/L)
Slovenian: Bolniki (%), ki so dosegli HbA1c < 7 % 74 Glukoza v plazmi na tešče (mmol/l) Izhodišče (povprečje)
English: Each pen contains 1.5 ml of solution, delivering 4 doses of 0.25 mg.
Slovenian: En injekcijski peresnik vsebuje 1,5 ml raztopine in omogoča 4 odmerke po 0,25 mg.
English: Glucagon secretion
Slovenian: Izločanje glukagona
English: Ozempic 0.5 mg solution for injection
Slovenian: Ozempic 0,5 mg raztopina za injiciranje
English: If there is not enough solution left in your pen for a full dose, do not use it. Use a new Ozempic pen.
Slovenian: Če v injekcijskem peresniku ni več dovolj raztopine za celotni odmerek, peresnika ne uporabite.
English: Change from baseline at week 56
Slovenian: Izhodišče (povprečje) Sprememba od izhodišča v 56. tednu
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients Disodium phosphate dihydrate Propylene glycol
Slovenian: FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi natrijev hidrogenfosfat dihidrat propilenglikol fenol klorovodikova kislina (za uravnavanje pH) natrijev hidroksid (za uravnavanje pH) voda za injekcije
English: Significant reductions in mean systolic blood pressure were observed when Ozempic 0.5 mg (3.5-5.1 mmHg) and 1 mg (5.4-7.3 mmHg) were used in combination with oral antidiabetic medicinal products or basal insulin.
Slovenian: Med uporabo 0,5 mg in 1 mg zdravila Ozempic v kombinaciji s peroralnimi antidiabetiki ali bazalnim insulinom so opažali značilno znižanje povprečnega sistoličnega krvnega tlaka (od 3,5 do 5,1 mmHg z 0,5-mg odmerkom ter od 5,4 do 7,3 mmHg z 1-mg odmerkom).
English: Each pen contains 1.5 ml of solution, delivering 4 doses of 0.5 mg.
Slovenian: En injekcijski peresnik vsebuje 1,5 ml raztopine in omogoča 4 odmerke po 0,5 mg.
English: Always use the dose counter and the dose pointer to see that 0.5 mg has been selected before injecting this medicine.
Slovenian: Pred injiciranjem zdravila s števcem in kazalnikom odmerka vedno preverite, da ste izbrali odmerek 0,5 mg.
English: Each dose contains 0.5 mg of semaglutide in 0.37 ml.
Slovenian: En odmerek vsebuje 0,5 mg semaglutida v 0,37 ml.
English: Always use the dose counter and the dose pointer to see that 0.25 mg has been selected before injecting this medicine.
Slovenian: Pred injiciranjem zdravila s števcem in kazalnikom odmerka vedno preverite, da ste izbrali odmerek 0,25 mg.
English: PHARMACEUTICAL FORM AND CONTENTS solution for injection
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA
English: The most commonly reported adverse reaction was nausea.
Slovenian: Najpogostejši neželeni učinek je bila navzea.
English: INFORMATION IN BRAILLE Ozempic 0.25 mg
Slovenian: Ozempic 0,25 mg
English: At week 40, the increase in pulse rate for Ozempic (0.5 mg and 1 mg) and dulaglutide (0.75 mg and 1.5 mg) was 2.4, 4.0, and 1.6, 2.1, beats/min, respectively.
Slovenian: V 40. tednu je bilo povišanje frekvence srčnega utripa pri bolnikih, ki so jemali zdravilo Ozempic 0,5 mg in zdravilo Ozempic 1 mg 2,4 oz. 4,0, pri bolnikih, ki so jemali dulaglutid (0.75 mg in 1.5 mg) pa se je srčna frekvenca povišala za 1,6 oz. 2,1 utrip na minuto.
English: • Press and hold down the dose button until the dose counter shows 0.
Slovenian: • Pritisnite na potisni gumb in ga držite, dokler se števec odmerka ne vrne na 0.
English: Each dose contains 1 mg of semaglutide in 0.74 ml solution.
Slovenian: En odmerek vsebuje 1 mg semaglutida v 0,74 ml raztopine.
English: Ozempic N (%)
Slovenian: N (%)
English: • constipation
Slovenian: • spahovanje
English: • low blood sugar (hypoglycaemia) when this medicine is used with another antidiabetic medicine
Slovenian: • prenizek krvni sladkor (hipoglikemija), če to zdravilo uporabljate sočasno s kakšnim drugim zdravilom za zdravljenje sladkorne bolezni Opozorilni znaki prenizkega krvnega sladkorja se lahko pojavijo nenadoma.
English: Each dose contains 0.25 mg of semaglutide in 0.19 ml.
Slovenian: En odmerek vsebuje 0,25 mg semaglutida v 0,19 ml.
English: Semaglutide did not change the overall exposure or Cmax of R- and S-warfarin following a single dose of warfarin (25 mg), and the pharmacodynamic effects of warfarin as measured by the international normalised ratio (INR) were not affected in a clinically relevant manner.
Slovenian: Varfarin Semaglutid po enkratnem odmerku varfarina (25 mg) ni spremenil celotne izpostavljenosti ali Cmax R
English: Ozempic 1 mg solution for injection in pre-filled pen semaglutide
Slovenian: Ozempic 1 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: At week 30, the change in HbA1c was -1.3%, -1.8% and0.4% for Ozempic 0.5 mg, Ozempic 1 mg, and placebo, respectively.
Slovenian: Ozempic -1,3 %, z 1 mg zdravila Ozempic -1,8 % in s placebom -0,4 %.
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE OF ADMINISTRATION Ozempic 1 mg injection semaglutide subcutaneous use
Slovenian: Ozempic 1 mg injekcija semaglutid za subkutano uporabo
English: -3.6 [-4.7, -2.4]a p <0.0001 (2-sided) for superiority
Slovenian: -3,6 [-4,7; -2,4]a ap < 0,0001 (2-stransko) za superiornost
English: DATE OF REVISION OF THE TEXT
Slovenian: sprememba od izhodišča
English: Count slowly:
Slovenian: počasi štejte:
English: METHOD OF ADMINISTRATION once weekly
Slovenian: Semaglutid uporabljajte enkrat na teden.
English: A significant and sustained reduction in body weight from baseline to week 104 was observed with Ozempic 0.5 mg and 1 mg vs placebo 0.5 mg and 1 mg, in addition to standard-of-care (-3.6 kg and -4.9 kg vs -0.7 kg and -0.5 kg , respectively) in SUSTAIN 6.
Slovenian: Ozempic 1 mg (-4,9 kg) v primerjavi s placebom 0,5 mg (-0,7 kg) in placebom 1 mg (-0,5 kg).
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE OF ADMINISTRATION Ozempic 0.25 mg injection semaglutide subcutaneous use
Slovenian: Ozempic 0,25 mg injekcija semaglutid za subkutano uporabo
English: Ozempic 1 mg solution for injection is available in the following pack sizes: 1 pen and 4 disposable NovoFine Plus needles.
Slovenian: Zdravilo Ozempic 1 mg raztopina za injiciranje je na voljo v naslednjih velikostih pakiranj:
English: Instructions on how to use Ozempic 0.25 mg solution for injection in pre-filled pen
Slovenian: Navodila za uporabo zdravila Ozempic 0,25 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku
English: • To see how much solution is left, use the dose counter: Turn the dose selector until the dose counter stops.
Slovenian: Koliko raztopine je še preostalo • Preostalo količino raztopine lahko preverite s pomočjo števca odmerka.
English: • tiredness
Slovenian: • omotica
English: How to store Ozempic
Slovenian: Shranjevanje zdravila Ozempic
English: Gastro-oesophageal reflux disease Eructation Flatulence
Slovenian: zaprtje, dispepsija, gastritis, gastroezofagealna refluksna bolezen,
English: Cholelithiasis
Slovenian: flatulenca
English: Increased heart rate has been observed with GLP-1 receptor agonists.
Slovenian: Med uporabo agonistov GLP-1 so opažali povečanje srčne frekvence.
English: Ozempic 0.25 mg solution for injection in pre-filled pen semaglutide
Slovenian: Ozempic 0,25 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: Ask your doctor, nurse or pharmacist about sharps disposal.
Slovenian: Za nasvet o odlaganju ostrih odpadkov prosite zdravnika, medicinsko sestro ali farmacevta.
English: Instructions on how to use Ozempic 0.5 mg solution for injection in pre-filled pen
Slovenian: Navodila za uporabo zdravila Ozempic 0,5 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku
English: Ozempic 0.25 mg solution for injection is available in the following pack size: 1 pen and 4 disposable NovoFine Plus needles.
Slovenian: Zdravilo Ozempic 0,25 mg raztopina za injiciranje je na voljo v naslednjih velikostih pakiranj:
English: Table 4 SUSTAIN 7: Results at week 40 Semaglutide 0.5 mg
Slovenian: SUSTAIN 1: Rezultati v 30. tednu semaglutid 0,5 mg semaglutid 1 mg placebo
English: Favours Ozempic
Slovenian: Ozempic
English: Each dose contains 0.25 mg of semaglutide in 0.19 ml solution.
Slovenian: En odmerek vsebuje 0,25 mg semaglutida v 0,19 ml raztopine.
English: If the solution looks cloudy or coloured, do not use the pen.
Slovenian: Če je raztopina motna ali obarvana, injekcijskega peresnika ne smete uporabiti.
English: Keep turning until the dose counter stops and shows 1 mg.
Slovenian: Vrtite ga toliko časa, da se števec odmerka ustavi in kaže
English: Hydrochloric acid (for pH adjustment) Sodium hydroxide (for pH adjustment) Water for injections
Slovenian: natrijev hidrogenfosfat dihidrat, propilenglikol, fenol, klorovodikovo kislino (za uravnavanje pH), natrijev hidroksid (za uravnavanje pH) in vodo za injekcije.
English: Ozempic 0.5 mg solution for injection is available in the following pack sizes: 1 pen and 4 disposable NovoFine Plus needles.
Slovenian: Zdravilo Ozempic 0,5 mg raztopina za injiciranje je na voljo v naslednjih velikostih pakiranj:
English: Each dose contains 0.5 mg of semaglutide in 0.37 ml solution.
Slovenian: En odmerek vsebuje 0,5 mg semaglutida v 0,37 ml raztopine.
English: Ozempic 0.5 mg solution for injection in pre-filled pen semaglutide
Slovenian: Ozempic 0,5 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE OF ADMINISTRATION Ozempic 0.5 mg injection semaglutide subcutaneous use
Slovenian: Ozempic 0,5 mg injekcija semaglutid za subkutano uporabo
English: NAME OF THE MEDICINAL PRODUCT Ozempic 1 mg solution for injection in pre-filled pen semaglutide
Slovenian: Navodilo za uporabo Ozempic 1 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: Fasting and postprandial glucose
Slovenian: Bolezni jeter, žolčnika in žolčevodov holelitiaza
English: Keep the pen cap on when the pen is not in use in order to protect it from light.
Slovenian: Kadar injekcijskega peresnika ne uporabljate, naj bo pokrit s pokrovčkom za zagotovitev zaščite pred svetlobo.
English: -4.2 [-4.9, -3.5]a ap <0.0001 (2-sided) for superiority
Slovenian: -4,2 [-4,9; -3,5]a ap < 0,0001 (2-stransko) za superiornost čas od randomizacije (tedni) Ozempic 0,5 mg sitagliptin
English: One pre-filled pen contains 4 mg semaglutide* in 3.0 ml solution.
Slovenian: En napolnjen injekcijski peresnik vsebuje 4 mg semaglutida v 3,0 ml raztopine.
English: Intent-to-Treat (ITT) Population (N) HbA1c (%) Baseline (mean) Change from baseline at week 56 Difference from exenatide [95% CI] -0.6 [-0.8, -0.4]a Patients (%) achieving HbA1c <7% FPG (mmol/L) Baseline (mean) Change from baseline at week 56 Body weight (kg) Baseline (mean) Change from baseline at week 56 Difference from exenatide [95% CI] -3.8 [-4.6, -3.0]a ap <0.0001 (2-sided) for superiority
Slovenian: Bolniki (%), ki so dosegli HbA1c < 7 % Glukoza v plazmi na tešče (mmol/l) Izhodišče (povprečje) Sprememba od izhodišča v 56. tednu Telesna masa (kg) Izhodišče (povprečje) Sprememba od izhodišča v 56. tednu
English: NAME OF THE MEDICINAL PRODUCT Ozempic 0.25 mg solution for injection in pre-filled pen semaglutide
Slovenian: Navodilo za uporabo Ozempic 0,25 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: Effects on the digestive system
Slovenian: Učinki na prebavila
English: Diabetic eye disease (retinopathy)
Slovenian: Očesne bolezni zapleti diabetične retinopatijeb
English: NAME OF THE MEDICINAL PRODUCT Ozempic 0.5 mg solution for injection in pre-filled pen semaglutide
Slovenian: Navodilo za uporabo Ozempic 0,5 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku semaglutid
English: Keep turning until the dose counter stops and shows 0.25 mg.
Slovenian: • Zavrtite izbirnik odmerka, da boste izbrali 0,25 mg. Vrtite ga toliko časa, da se števec odmerka ustavi in kaže
English: • being sick (vomiting)
Slovenian: • slabši apetit • vetrovi (napenjanje)
English: Injection site reactions (e.g. injection site rash, erythema) have been reported by 0.6% and 0.5% of patients receiving semaglutide 0.5 mg and 1 mg, respectively.
Slovenian: O reakcijah na mestu injiciranja (npr. izpuščaju ali eritemu na mestu injiciranja) je poročalo 0,6 %
English: Difference from insulin glargine [95% CI] -4.6 [-5.3, -4.0]
Slovenian: Sprememba od izhodišča v 40. tednu -4,6 Razlika v primerjavi z dulaglutidom [95 % IZ]
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON
Slovenian: Izgled zdravila Ozempic in vsebina pakiranja
English: Figure 1 Mean change in HbA1c (%) and body weight (kg) from baseline to week 56
Slovenian: Slika 1: Povprečna sprememba HbA1c (%) in telesne mase (kg) od izhodišča do 56. tedna SUSTAIN 7 - Zdravilo Ozempic v primerjavi z dulaglutidom, oba v kombinaciji z metforminom
English: MA (EU) Number
Slovenian: Številka (EU) dovoljenja za promet>
English: Strength
Slovenian: pakiranja
English: Immediate Packaging
Slovenian: Stična ovojnina Vsebina
English: The dose and number of injections depend on the patient's response.
Slovenian: Odmerek in število injekcij sta odvisna od odziva bolnika.
English: Further information on NeuroBloc can be found on the Agency's website ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Slovenian: Nadaljnje informacije za zdravilo NeuroBloc so na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: The European Medicines Agency decided that NeuroBloc's benefits are greater than its risks and it can be authorised for use in the EU.
Slovenian: Evropska agencija za zdravila je zaključila, da so koristi zdravila NeuroBloc večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
English: Most patients who had a response to NeuroBloc by the fourth week had returned to their original condition 12 to 16 weeks after the injection.
Slovenian: Pri večini bolnikov, ki so se do četrtega tedna odzvali na zdravilo NeuroBloc, je po 12 do 16 tednih po prejeti injekciji prišlo do povrnitve v začetno stanje.
English: NeuroBloc (botulinum toxin type B) EMA/356522/2018
Slovenian: NeuroBloc (botulinski toksin vrste B) EMA/356522/2018
English: Other information about NeuroBloc
Slovenian: Druge informacije o zdravilu NeuroBloc
English: What measures are being taken to ensure the safe and effective use of NeuroBloc?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila NeuroBloc?
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of NeuroBloc have been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila NeuroBloc upoštevati zdravstveni delavci in bolniki, so vključeni v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: NeuroBloc received a marketing authorisation valid throughout the EU on 22 January 2001.
Slovenian: Za zdravilo NeuroBloc je bilo 22. januarja 2001 izdano dovoljenje za promet, veljavno po vsej EU.
English: As for all medicines, data on the use of NeuroBloc are continuously monitored.
Slovenian: Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila NeuroBloc stalno spremljajo.
English: NeuroBloc was more effective than placebo (a dummy treatment) at improving symptoms of cervical dystonia in four studies involving a total of 392 adults.
Slovenian: Zdravilo NeuroBloc je bilo učinkovitejše od placeba (zdravila brez učinkovine) pri izboljševanju simptomov cervikalne distonije v štirih študijah, ki so vključevale skupaj 392 odraslih.
English: Side effects reported with NeuroBloc are carefully evaluated and any necessary action taken to protect patients.
Slovenian: Neželeni učinki, o katerih so poročali pri zdravilu NeuroBloc, se skrbno ovrednotijo in po potrebi se sprejmejo ukrepi za zaščito bolnikov.
English: NeuroBloc must not be used in patients with other neuromuscular (nerve and muscle) disorders.
Slovenian: Zdravilo NeuroBloc se ne sme uporabljati pri bolnikih z drugimi nevromuskularnimi boleznimi (boleznimi živcev in mišic).
English: For more information about using NeuroBloc, see the package leaflet or contact your doctor or pharmacist.
Slovenian: Za več informacij glede uporabe zdravila NeuroBloc glejte navodilo za uporabo ali se posvetujte z zdravnikom ali farmacevtom.
English: What benefits of Neurobloc have been shown in studies?
Slovenian: Kakšne koristi zdravila NeuroBloc so se pokazale v študijah?
English: Why is NeuroBloc authorised in the EU?
Slovenian: Zakaj je bilo zdravilo NeuroBloc odobreno v EU?
English: NeuroBloc is available as a solution for injection (5,000 units [U] per millilitre) and it can only be obtained with a prescription.
Slovenian: Zdravilo NeuroBloc je na voljo v obliki raztopine za injiciranje (5 000 enot [E] na mililiter), njegovo predpisovanje in izdaja pa je le na recept.
English: The toxin reduces the release of acetylcholine from the nerve endings.
Slovenian: Toksin zmanjša sproščanje acetilholina iz živčnih končičev.
English: When injected directly into a muscle it reduces the release of acetylcholine and muscle contraction in the affected neck or shoulder muscles, thereby relieving the patient's symptoms.
Slovenian: Če je injiciran neposredno v mišico, zmanjša sproščanje acetilholina in krčenje prizadetih mišic v vratu ali ramenih, kar pomaga ublažiti bolnikove simptome.
English: Cervical dystonia, which is also known as torticollis, is a disorder when the neck muscles contract, causing abnormal movement and twisting of the neck and unusual positioning of the head.
Slovenian: Cervikalna distonija, imenovana tudi tortikolis, je bolezen, pri kateri se mišice vratu krčijo, kar povzroča nenormalno premikanje in zvijanje vratu ter nenavaden položaj glave.
English: An overview of NeuroBloc and why it is authorised in the EU
Slovenian: Pregled zdravila NeuroBloc in zakaj je odobreno v EU
English: In NeuroBloc, the toxin is used as a muscle relaxant.
Slovenian: V zdravilu NeuroBloc je toksin uporabljen kot mišični relaksant.
English: NeuroBloc is a medicine used to treat cervical dystonia in adults.
Slovenian: NeuroBloc je zdravilo, ki se uporablja za zdravljenje cervikalne distonije pri odraslih.
English: The most common side effects with NeuroBloc (which may affect more than 1 in 10 people) are dry mouth, headache (in patients new to treatment with botulinum toxins), dysphagia (difficulty swallowing) and pain at the site of the injection.
Slovenian: Najpogostejši neželeni učinki zdravila NeuroBloc (opaženi pri več kot 1 od 10 bolnikov) so suha usta, glavobol (pri bolnikih, ki zdravljenje z botulinskimi toksini šele začenjajo), disfagija (težave s požiranjem) in bolečina na mestu injiciranja.
English: What is NeuroBloc and what is it used for?
Slovenian: Kaj je zdravilo NeuroBloc in za kaj se uporablja?
English: What are the risks associated with NeuroBloc?
Slovenian: Kakšna tveganja so povezana z zdravilom NeuroBloc?
English: The effect of an injection of NeuroBloc gradually wears off over time.
Slovenian: Učinek injekcije zdravila NeuroBloc sčasoma izzveni.
English: NeuroBloc treatment starts with 10,000 U, divided into equal doses and injected directly into the two to four muscles in the neck and shoulders that are most affected.
Slovenian: Začetni odmerek zdravila NeuroBloc je 10 000 enot in ga je treba razdeliti v enake odmerke, ki se vbrizgajo neposredno v dve do štiri najbolj prizadete mišice vratu in ramen.
English: The active substance in NeuroBloc, botulinum toxin type B, is a well-known toxic substance produced by the bacterium Clostridium botulinum.
Slovenian: Učinkovina v zdravilu NeuroBloc, botulinski toksin vrste B, je dobro znana strupena snov, ki jo tvori bakterija Clostridium botulinum.
English: Acetylcholine is needed to transfer electrical impulses from the nerves to the muscles in order for the muscles to contract.
Slovenian: Acetilholin je potreben za prenos električnih impulzov iz živcev v mišice, da se te krčijo.
English: NeuroBloc (botulinum toxin type B)
Slovenian: NeuroBloc (botulinski toksin vrste B)
English: The toxin is the cause of a type of food poisoning called botulism, where patients suffer from muscle weakness and paralysis.
Slovenian: Ta toksin povzroča botulizem, vrsto zastrupitve s hrano, pri kateri se pri bolnikih pojavita šibkost mišičja in paraliza.
English: For the full list of side effects reported with NeuroBloc, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila NeuroBloc, glejte navodilo za uporabo.
English: It is only used in hospitals, by a doctor who has experience in the treatment of cervical dystonia and in the use of botulinum toxins.
Slovenian: Zdravilo NeuroBloc lakko uporablja le v bolnišnici, daje pa ga lahko le zdravnik, ki ima izkušnje z zdravljenjem cervikalne distonije in uporabo botulinskih toksinov.
English: The medicine improved the TWSTRS score of the non-responders to type A botulinum toxin as well as the score of the responders.
Slovenian: Zdravilo je izboljšalo rezultate tako pri bolnikih, ki se niso odzvali na botulinski toksin vrste A, kot pri tistih, ki so se nanj odzvali.
English: How does NeuroBloc work?
Slovenian: Kako zdravilo NeuroBloc deluje?