FrancophonIA/ELRC3.0 huggingface dataset:
English: SOLYMBIC can also be used to treat severe, active and progressive rheumatoid arthritis without previous methotrexate treatment.
Croatian: U svrhu liječenja teškog, aktivnog i progresivnog reumatoidnog artritisa, SOLYMBIC se može primijeniti i bez prethodnog liječenja metotreksatom.
English: System Organ Class Frequency Adverse Reaction Rare
Croatian: Poremećaji reproduktivnog sustava i dojki manje često erektilna disfunkcija
English: SOLYMBIC 20 mg solution for injection in pre-filled syringe 0.4 mL solution in pre-filled syringe (type I glass) with a plunger stopper (bromobutyl rubber) and a stainless steel needle with a needle shield (thermoplastic elastomer).
Croatian: SOLYMBIC 20 mg otopina za injekciju u napunjenoj štrcaljki 0,4 ml otopine u napunjenoj štrcaljki (staklo tipa I), s čepom klipa (bromobutilna guma) i iglom od nehrđajućeg čelika sa zaštitom za iglu (termoplastični elastomer).
English: SOLYMBIC is administered by injection under the skin (subcutaneous injection).
Croatian: SOLYMBIC se primjenjuje potkožnom injekcijom (supkutana injekcija).
English: In non-infectious uveitis, corticosteroids or other medicines that influence the immune system may be continued while using SOLYMBIC.
Croatian: Kod nezaraznog uveitisa se uz lijek SOLYMBIC mogu nastaviti primjenjivati kortikosteroidi ili drugi lijekovi koji utječu na imunološki sustav.
English: Packs sizes of one, two, four and six pre-filled syringes.
Croatian: Pakiranja od jedne, dvije, četriri ili šest napunjenih štrcaljki.
English: SOLYMBIC 40 mg solution for injection in pre-filled syringe 0.8 mL solution in pre-filled syringe (type I glass) with a plunger stopper (bromobutyl rubber) and a stainless steel needle with a needle shield (thermoplastic elastomer).
Croatian: SOLYMBIC 40 mg otopina za injekciju u napunjenoj štrcaljki 0,8 ml otopine u napunjenoj štrcaljki (staklo tipa I), s čepom klipa (bromobutilna guma) i iglom od nehrđajućeg čelika sa zaštitom za iglu (termoplastični elastomer).
English: You are advised to avoid becoming pregnant and must use adequate contraception while using SOLYMBIC and for at least 5 months after the last SOLYMBIC treatment.
Croatian: Savjetuje se da za vrijeme liječenja lijekom SOLYMBIC izbjegavate začeće te stoga u tom razdoblju morate primjenjivati primjerenu kontracepciju s kojom treba nastaviti barem 5 mjeseci nakon zadnje doze lijeka SOLYMBIC.
English: MTX = methotrexate b P = 0.027, adalimumab 0.8 mg/kg versus MTX
Croatian: P = 0,027, adalimumab 0,8 mg/kg naspram MTX-a c
English: Greater improvements at week 12 from baseline compared to placebo were demonstrated in skinspecific health-related quality of life, as measured by the Dermatology Life Quality Index (DLQI; Studies HS-I and HS-II), patient global satisfaction with medication treatment as measured by the Treatment Satisfaction Questionnaire-medication (TSQM; Studies HS-I and HS-II), and physical health as measured by the physical component summary score of the SF-36 (study HS-I).
Croatian: Treatment Satisfaction Questionnaire - medication [TSQM]; ispitivanja HS-I i HS-II) i fizičko zdravlje, koje se određivalo na temelju rezultata za cjelokupnu fizičku komponentu upitnika SF-36 (ispitivanje HS-I).
English: SOLYMBIC is used to treat moderate to severe plaque psoriasis in adults.
Croatian: SOLYMBIC je namijenjen liječenju umjerene do teške plak psorijaze u odraslih.
English: PGA: Clear/minimal b a Percent of patients achieving PASI75 response was calculated as centre-adjusted rate b p < 0.001, adalimumab versus placebo
Croatian: Postotak bolesnika s rezultatom PASI 75 izražen kao stopa prilagođena istraživačkom centru b p < 0,001, adalimumab naspram placebo
English: Some subjects who experience insufficient response may benefit from an increase in dosing frequency to 20 mg SOLYMBIC every week.
Croatian: Pojedini bolesnici u kojih se ne postigne zadovoljavajući odgovor mogli bi imati koristi od povećanja učestalosti doziranja na 20 mg lijeka SOLYMBIC svaki tjedan.
English: SOLYMBIC is used to treat psoriatic arthritis in adults.
Croatian: SOLYMBIC je namijenjen liječenju psorijatičnog artritisa u odraslih.
English: Erosion score JSN
Croatian: Ukupan zbroj bodova prema Sharpu c rezultat za eroziju JSN
English: Clinical efficacy and safety
Croatian: Klinička djelotvornost i sigurnost Reumatoidni artritis
English: SOLYMBIC 20 mg syringe
Croatian: SOLYMBIC 20 mg štrcaljka
English: SOLYMBIC 40 mg pen
Croatian: SOLYMBIC 40 mg brizgalica
English: Use a new SOLYMBIC pre-filled pen.
Croatian: Primijenite novu SOLYMBIC napunjenu brizgalicu.
English: Intestinal infections (including gastroenteritis viral), Skin and soft tissue infections (including paronychia, cellulitis, impetigo, necrotising fasciitis and herpes zoster), Ear infections,
Croatian: često sistemske infekcije (uključujući sepsu, kandidijazu i gripu), intestinalne infekcije (uključujući virusni gastroenteritis), infekcije kože i mekog tkiva (uključujući paronihiju, celulitis, impetigo, nekrotizirajući fasciitis i herpes zoster), infekcije uha, infekcije usne šupljine (uključujući herpes simpleks, herpes usne infekcije reproduktivnog sustava (uključujući vulvovaginalne mikoze), infekcije mokraćnog sustava (uključujući pijelonefritis),
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE NALJEPNICA ZA NAPUNJENU ŠTRCALJKU
English: SOLYMBIC is indicated for the treatment of adults with severe active ankylosing spondylitis who have had an inadequate response to conventional therapy.
Croatian: SOLYMBIC je indiciran za liječenje teškog oblika aktivnog ankilozantnog spondilitisa u odraslih osoba u kojih nije postignut zadovoljavajući odgovor na konvencionalno liječenje.
English: There have been cases of cancers other than lymphoma in patients with a specific type of lung disease called Chronic Obstructive Pulmonary Disease (COPD) treated with another TNF blocker.
Croatian: • U bolesnika koji boluju od specifične plućne bolesti koja se naziva kronična opstruktivna plućna bolest (KOPB) i primali su neke druge TNF blokatore, zabilježeni su i drugačiji oblici tumora osim limfoma.
English: Not known Worsening of symptoms of dermatomyositis
Croatian: manje često noćno znojenje, rijetko nepoznato pogoršanje simptoma dermatomiozitisa
English: If you do not respond well enough to these medicines, you will be given SOLYMBIC to treat your rheumatoid arthritis.
Croatian: Ukoliko na njih ne reagirate dovoljno dobro, u svrhu liječenja Vašeg reumatoidnog artritisa bit će Vam propisan lijek SOLYMBIC.
English: Bath Ankylosing Spondylitis Disease Activity Index c Ankylosing Spondylitis Disease Activity Score d mean change from baseline e n = 91 placebo and n = 87 adalimumab f high sensitivity C-Reactive Protein (mg/L) g n = 73 placebo and n = 70 adalimumab h
Croatian: Srednja promjena od početne vrijednosti e n = 91 za placebo i n = 87 za adalimumab f
English: SOLYMBIC is indicated for treatment of moderately to severely active Crohn's disease, in adult patients who have not responded despite a full and adequate course of therapy with a corticosteroid and/or an immunosuppressant; or who are intolerant to or have medical contraindications for such therapies.
Croatian: SOLYMBIC je indiciran za liječenje umjerenog do teškog oblika aktivne Crohnove bolesti u odraslih bolesnika u kojih unatoč prethodnom potpunom i odgovarajućem tijeku liječenja kortikosteroidima i/ili imunosupresivima nije postignut odgovor ili kod bolesnika koji ih ne podnose ili im je takva terapija kontraindicirana.
English: If a faster response is required, your doctor may prescribe an initial dose of 80 mg (as two 40 mg injections in 1 day) followed by 40 mg two weeks later.
Croatian: Ako je potreban brži odgovor na liječenje, liječnik može propisati početnu dozu od 80 mg (2 injekcije od 40 mg u jednom danu) i zatim 40 mg nakon dva tjedna.
English: In RA study V with early rheumatoid arthritis patients who were methotrexate naïve, combination therapy with adalimumab and methotrexate led to faster and significantly greater ACR responses than methotrexate monotherapy and adalimumab monotherapy at week 52 and responses were sustained at week 104 (see table 5).
Croatian: U ispitivanju RA V, u kojem su obuhvaćeni bolesnici u ranoj fazi reumatoidnog artritisa koji do tada nisu bili liječeni metotreksatom, kombiniranom primjenom adalimumaba i metotreksata tijekom 52 tjedna postignut je brži i statistički značajno bolji ACR odgovor nego uz monoterapiju metotreksatom, odnosno adalimumabom.
English: Tell your doctor immediately if you notice any of the following:
Croatian: Primijetite li išta od dolje navedenog, odmah obavijestite svog liječnika:
English: In patients with uveitis, a loading dose of 80 mg adalimumab on week 0 followed by 40 mg adalimumab every other week starting at week 1, resulted in mean steady-state concentrations of approximately 8 to 10 μg/mL.
Croatian: U bolesnika s uveitisom, udarna doza adalimumaba od 80 mg u nultom tjednu i zatim 40 mg svaki drugi tjedan, počevši od 1. tjedna, dovela je do srednje vrijednosti koncentracija u stanju dinamičke ravnoteže od približno 8 - 10 µg/ml.
English: SOLYMBIC 20 mg solution for injection in pre-filled syringe Each single dose pre-filled syringe contains 20 mg of adalimumab in 0.4 mL (50 mg/mL) solution.
Croatian: SOLYMBIC 20 mg otopina za injekciju u napunjenoj štrcaljki Jedna jednodozna napunjena štrcaljka sadrži 20 mg adalimumaba u 0,4 ml otopine (50 mg/ml).
English: Methotrexate should be continued during treatment with SOLYMBIC.
Croatian: Za vrijeme liječenja lijekom SOLYMBIC treba nastaviti primjenu metotreksata.
English: Very common Rash (including exfoliative rash) Worsening or new onset of psoriasis (including palmoplantar pustular psoriasis)
Croatian: Poremećaji kože i potkožnog tkiva vrlo često osip (uključujući eksfolijativni osip) često pogoršanje ili nova pojava psorijaze (uključujući palmoplantarnu stvaranje modrica (uključujući purpuru), dermatitis (uključujući ekcem), pojačano znojenje (hiperhidroza),
English: Oedema,
Croatian: • osip,
English: Uncommon Pulmonary embolism Interstitial lung disease, Chronic obstructive pulmonary disease, Pneumonitis,
Croatian: često astma, dispneja, kašalj manje često plućna embolija intersticijska plućna bolest, kronična opstruktivna plućna bolest, pneumonitis pleuralna efuzija rijetko plućna fibroza
English: Use a new SOLYMBIC pre-filled syringe.
Croatian: Primijenite novu SOLYMBIC napunjenu štrcaljku.
English: Adalimumab 40 mg every other week was assessed in 185 patients in one randomised, 12 week double-blind, placebo-controlled study in patients with active non-radiographic axial spondyloarthritis (mean baseline score of disease activity [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)] was 6.4 for patients treated with adalimumab and 6.5 for those on placebo) who have had an inadequate response to or intolerance to ≥ 1 NSAIDs, or a contraindication for NSAIDs.
Croatian: Bath Ankylosing Spondilitis Disease Activity Index, BASDAI)] bila je 6,4 u skupini bolesnika koji su primali adalimumab i 6,5 u skupini koja je primala placebo) koji nisu imali zadovoljavajući odgovor na ≥ 1 NSAIL-a ili ga nisu podnosili, ili su imali kontraindikaciju za primjenu NSAIL-a.
English: Not applicable, SOLYMBIC is only available as 20 mg and 40 mg pre-filled syringe and 40 mg pre-filled pen
Croatian: Nije primjenjivo, SOLYMBIC je jedino dostupna kao napunjena štrcaljka od 20 mg i 40 mg i kao napunjena brizgalica od 40 mg
English: Glucocorticoids, salicylates, non-steroidal anti-inflammatory drugs, or analgesics can be continued during treatment with SOLYMBIC.
Croatian: Za vrijeme liječenja lijekom SOLYMBIC može se nastaviti s davanjem glukokortikoida, salicilata, nesteroidnih protuupalnih lijekova ili analgetika.
English: Paediatric hidradenitis suppurativa
Croatian: Gnojni hidradenitis (Hidradenitis suppurativa)
English: If you do not respond well enough to these medicines, you will be given SOLYMBIC to reduce the signs and symptoms of your Crohn's disease.
Croatian: Ako na njih ne reagirate dovoljno dobro, u svrhu smanjenja znakova i simptoma Crohnove bolesti bit će Vam propisan lijek SOLYMBIC.
English: SOLYMBIC is used to treat ulcerative colitis in adults.
Croatian: SOLYMBIC je namijenjen liječenju ulceroznog kolitisa u odraslih.
English: The needle cover of the pre-filled syringe or pen is made from dry natural rubber (a derivative of latex), which may cause allergic reactions.
Croatian: Pokrov igle napunjene štrcaljke ili brizgalice napravljen je od suhe prirodne gume (derivat lateksa) koja može uzrokovati alergijske reakcije.
English: SOLYMBIC is only available as 20 mg and 40 mg pre-filled syringe and 40 mg pre-filled pen.
Croatian: SOLYMBIC je dostupan samo kao napunjena štrcaljka od 20 mg i 40 mg i kao napunjena brizgalica od 40 mg.
English: SOLYMBIC 40 mg injection adalimumab
Croatian: SOLYMBIC 40 mg injekcija adalimumab s.c.
English: The usual dose regimen is 40 mg initially followed by 20 mg two weeks later.
Croatian: Uobičajena početna doza lijeka je 40 mg, nakon čega poslije dva tjedna slijedi doza od 20 mg.
English: Certain vaccines may cause infections and should not be given while receiving SOLYMBIC.
Croatian: • Za vrijeme liječenja lijekom SOLYMBIC ne smiju se primiti određena cjepiva jer mogu uzrokovati infekcije.
English: In case there is a need for a more rapid response to therapy, the regimen 80 mg at week 0 (dose can be administered as two injections in one day), 40 mg at week 2 can be used, with the awareness that the risk for adverse events may be higher with use of the higher induction dose.
Croatian: U slučaju kada je potreban brži odgovor na liječenje, može se primijeniti 80 mg u nultom tjednu (lijek se može dati kao dvije injekcije u jednom danu) i 40 mg u drugom tjednu, imajući na umu da rizik od nuspojava može biti veći kod primjene više indukcijske doze.
English: SPARCC MRI Spine d,j a Assessment of Spondyloarthritis International Society b
Croatian: Assessment of Spondyloarthritis International Society)
English: d score a methotrexate b
Croatian: MTX = metotreksat b
English: The usual dose regimen for hidradenitis suppurativa is an initial dose of 160 mg (as four 40 mg injections in one day or two 40 mg injections per day for two consecutive days), followed by an 80 mg dose (as two 40 mg injections on the same day) two weeks later.
Croatian: Uobičajen režim doziranja za gnojni hidradenitis je početna doza od 160 mg (u obliku 4 injekcije od 40 mg u jednom danu ili 2 injekcije od 40 mg na dan, tijekom dva uzastopna dana), nakon koje se dva tjedna kasnije primjenjuje doza od 80 mg (u obliku 2 injekcije od 40 mg u istom danu).
English: Ankylosing spondylitis and axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, are inflammatory diseases of the spine.
Croatian: Ankilozantni spondilitis i aksijalni spondiloartritis bez radiološkog dokaza AS-a upalne su bolesti kralježnice.
English: The needle cover of the pre-filled syringe is made from dry natural rubber (a derivative of latex), which may cause allergic reactions.
Croatian: Pokrov igle napunjene štrcaljke je napravljen od suhe prirodne gume (derivat lateksa) koja može uzrokovati alergijske reakcije.
English: SOLYMBIC 20 mg injection adalimumab
Croatian: SOLYMBIC 20 mg injekcija adalimumab s.c.
English: The recommended dose of SOLYMBIC for adult patients with rheumatoid arthritis is 40 mg adalimumab administered every other week as a single dose via subcutaneous injection.
Croatian: U odraslih bolesnika s reumatoidnim artritisom preporučena doza adalimumaba iznosi 40 mg, a daje se kao jednokratna doza svaka dva tjedna supkutanom injekcijom.
English: SOLYMBIC 20 mg solution for injection in pre-filled syringe SOLYMBIC 40 mg solution for injection in pre-filled syringe Solution for injection.
Croatian: SOLYMBIC 20 mg otopina za injekciju u napunjenoj štrcaljki SOLYMBIC 40 mg otopina za injekciju u napunjenoj štrcaljki Otopina za injekciju.
English: The recommended SOLYMBIC dose regimen for adult patients with hidradenitis suppurativa (HS) is 160 mg initially at day 1 (given as four 40 mg injections in one day or as two 40 mg injections per day for two consecutive days), followed by 80 mg two weeks later at day 15 (given as two 40 mg injections in one day).
Croatian: Preporučen režim doziranja lijeka SOLYMBIC za odrasle bolesnike s gnojnim hidradenitisom je početna doza od 160 mg prvoga dana (primijenjena u obliku četiri injekcije od 40 mg u jednom danu ili dvije injekcije od 40 mg na dan tijekom dva uzastopna dana), nakon koje slijedi doza od 80 mg dva tjedna kasnije, 15. dana (primijenjena u obliku dvije injekcije od 40 mg u jednom danu).
English: If you take SOLYMBIC the risk of getting lymphoma, leukaemia, or other cancers may increase.
Croatian: Rizik obolijevanja od limfoma, leukemije ili drugih tumora može se povećati ako primjenjujete lijek SOLYMBIC.
English: The recommended dose of SOLYMBIC for patients with ankylosing spondylitis, axial spondyloarthritis without radiographic evidence of AS and for patients with psoriatic arthritis is 40 mg adalimumab administered every other week as a single dose via subcutaneous injection.
Croatian: U bolesnika s ankilozantnim spondilitisom, aksijalnim spondiloartritisom bez radiološkog dokaza AS- a te u bolesnika sa psorijatičnim artritisom preporučena doza adalimumaba iznosi 40 mg, a daje se kao jednokratna doza svaka dva tjedna supkutanom injekcijom.
English: K. Discard the used pre-filled pen and the yellow cap.
Croatian: Odložite iskorištenu brizgalicu i žuti zatvarač igle.
English: SOLYMBIC 20 mg solution for injection in pre-filled syringe SOLYMBIC 40 mg solution for injection in pre-filled syringe adalimumab
Croatian: SOLYMBIC 20 mg otopina za injekciju u napunjenoj štrcaljki SOLYMBIC 40 mg otopina za injekciju u napunjenoj štrcaljki adalimumab
English: * p < 0.001 for adalimumab versus placebo pairwise comparisons of proportions ** p < 0.02 for adalimumab versus placebo pairwise comparisons of proportions a
Croatian: * p < 0,001 za adalimumab naspram placeba, sparena usporedba udjela **p < 0,02 za adalimumab naspram placeba, sparena usporedba udjela a Onih koji su na početku uzimali kortikosteroide
English: Some subjects who experience insufficient response may benefit from an increase in dosing frequency to 40 mg SOLYMBIC every week.
Croatian: Pojedini bolesnici u kojih se ne postigne zadovoljavajući odgovor mogli bi imati koristi od povećanja učestalosti doziranja na 40 mg lijeka SOLYMBIC svaki tjedan.
English: Beyond 16 weeks, patients with inadequate response may benefit from an increase in dosing frequency to 40 mg every week.
Croatian: U bolesnika u kojih nije postignut zadovoljavajući odgovor nakon 16 tjedana, možda će biti korisno povećati učestalost doziranja na 40 mg lijeka svaki tjedan.
English: SOLYMBIC 40 mg solution for injection in pre-filled syringe Each single dose pre-filled syringe contains 40 mg of adalimumab in 0.8 mL (50 mg/mL) solution.
Croatian: SOLYMBIC 40 mg otopina za injekciju u napunjenoj štrcaljki Jedna jednodozna napunjena štrcaljka sadrži 40 mg adalimumaba u 0,8 ml otopine (50 mg/ml).
English: 6 SureClick pre-filled pens.
Croatian: 6 SureClick napunjenih brizgalica.
English: The recommended SOLYMBIC induction dose regimen for adult patients with moderately to severely active Crohn's disease is 80 mg at week 0 followed by 40 mg at week 2.
Croatian: Preporučena indukcijska doza lijeka SOLYMBIC u odraslih bolesnika s umjerenom do teškom aktivnom Crohnovom bolešću je 80 mg u nultom tjednu, praćena dozom od 40 mg u drugom tjednu.
English: ≥ 4 or > 20% BSA involvement or > 10% BSA involvement with very thick lesions or PASI ≥ 20 or ≥ 10 with clinically relevant facial, genital, or hand/foot involvement) who were inadequately controlled with topical therapy and heliotherapy or phototherapy.
Croatian: Djelotvornost adalimumaba ocjenjivala se u randomiziranom, dvostruko slijepom, kontroliranom ispitivanju provedenom u 114 pedijatrijskih bolesnika u dobi od 4 ili više godina s teškom kroničnom plak psorijazom (koja se definirala kao PGA rezultat od ≥ 4 ili zahvaćenost površine tijela od > 20% ili zahvaćenost površine tijela od > 10% s vrlo debelim lezijama ili PASI rezultat od ≥ 20 ili ≥ 10 uz klinički značajnu zahvaćenost lica, genitalija ili šaka/stopala) u kojih bolest nije bila dovoljno dobro kontrolirana topikalnom terapijom i helioterapijom ili fototerapijom.
English: Using your SOLYMBIC pre-filled syringe
Croatian: Primjena SOLYMBIC napunjenih štrcaljki
English: SOLYMBIC 20 mg solution for injection in pre-filled syringe.
Croatian: SOLYMBIC 20 mg otopina za injekciju u napunjenoj štrcaljki.
English: Depending on your response, your doctor may increase the dose to 40 mg every week.
Croatian: Ovisno o odgovoru na liječenje, liječnik Vam može povećati doziranje na 40 mg svaki tjedan.
English: The recommended SOLYMBIC induction dose regimen for paediatric subjects with severe Crohn's disease is 40 mg at week 0 followed by 20 mg at week 2.
Croatian: Preporučena indukcijska doza lijeka SOLYMBIC u pedijatrijskih bolesnika s teškom Crohnovom bolesti je 40 mg u nultom tjednu i 20 mg u drugom tjednu.
English: Haematoma
Croatian: Imunogenost
English: SOLYMBIC therapy should not be continued in patients failing to respond within this time period.
Croatian: U bolesnika u kojih u ovom razdoblju ne bude odgovora, liječenje lijekom SOLYMBIC ne treba nastaviti.
English: If you do not respond well enough to these medicines, you will be given SOLYMBIC to treat your enthesitis-related arthritis.
Croatian: Ako na njih ne reagirate dovoljno dobro, u svrhu liječenja artritisa povezanog s entezitisom bit će Vam propisan lijek SOLYMBIC.
English: The usual dose regimen is 80 mg initially followed by 40 mg two weeks later.
Croatian: Uobičajena početna doza lijeka je 80 mg, nakon čega poslije dva tjedna slijedi doza od 40 mg.
English: The recommended dose of SOLYMBIC for patients aged 4 to 17 years with plaque psoriasis depends on the weight of your child. SOLYMBIC should only be used in patients weighing either 23 to 28 kg or 47 kg and greater.
Croatian: SOLYMBIC se smije primjenjivati samo kod bolesnika tjelesne težine ili od 23 do 28 kg ili od 47 kg i više.
English: SOLYMBIC single use pre-filled syringe For subcutaneous use
Croatian: SOLYMBIC napunjena štrcaljka za jednokratnu primjenu
English: Crohn's disease in adults and children Crohn's disease is an inflammatory disease of the digestive tract.
Croatian: Crohnova bolest je upalna bolest probavnog sustava.
English: SOLYMBIC 40 mg syringe
Croatian: SOLYMBIC 40 mg štrcaljka
English: If a faster response is required, your doctor may prescribe an initial dose of 160 mg (as four 40 mg injections in 1 day or as two 40 mg injections per day for 2 consecutive days) followed by 80 mg two weeks later.
Croatian: Ako je potreban brži odgovor na liječenje, liječnik može propisati početnu dozu od 160 mg (4 injekcije od 40 mg u jednom danu ili 2 injekcije od 40 mg u 2 uzastopna dana) i zatim 80 mg nakon dva tjedna.
English: In case there is a need for a more rapid response to therapy, the regimen 160 mg at week 0 (dose can be administered as four injections in one day or as two injections per day for two consecutive days), 80 mg at week 2 can be used, with the awareness that the risk for adverse events may be higher with use of the higher induction dose.
Croatian: U slučaju kada je potreban brži odgovor na liječenje, može se primijeniti 160 mg u nultom tjednu (lijek se može dati kao četiri injekcije u jednom danu ili kao dvije injekcije na dan kroz dva uzastopna dana) i 80 mg u drugom tjednu, imajući na umu da rizik od nuspojava može biti veći kod primjene više indukcijske doze.
English: SOLYMBIC 40 mg solution for injection in pre-filled pen Each single dose pre-filled pen contains 40 mg of adalimumab in 0.8 mL (50 mg/mL) solution.
Croatian: SOLYMBIC 40 mg otopina za injekciju u napunjenoj brizgalici Jedna jednodozna napunjena brizgalica sadrži 40 mg adalimumaba u 0,8 ml otopine (50 mg/ml).
English: Pinch method
Croatian: a metotreksat