FrancophonIA/ELRC3.0 huggingface dataset:
English: The safety of the veterinary medicinal product has not been established during pregnancy and lactation or in animals intended for breeding.
Estonian: Veterinaarravimi ohutus tiinuse ja laktatsiooni perioodil ning aretuses kasutatavatel loomadel ei ole piisavalt tõestatud.
English: No clinically significant adverse reactions were observed in kittens from 8 weeks of age treated with up to 5 times the maximum recommended dose of the product for up to 8 consecutive treatments at 28 day intervals, apart from a single cat administered 5 times the maximum dose that displayed transient hypersensitivity to touch, piloerection, mydriasis and mild tremor which resolved without treatment.
Estonian: Üle 8 kuu vanuste kassipoegade ravimisel viiekordse maksimaalse soovitatava annusega kaheksal järjestikusel manustamiskorral 28-päevaste intervallidega kliiniliselt olulisi kõrvaltoimeid ei täheldatud, välja arvatud ühel viiekordse annuse saanud kassil, kellel esines mööduv ülitundlikkus puudutuste suhtes, piloerektsioon, pupillide laienemine ja kerge värisemine, mis möödus ilma ravita.
English: Felisecto Plus 60 mg/10 mg (green cap)
Estonian: Felisecto Plus 60 mg/10 mg (rohelise korgiga)
English: as well as mites (Otodectes cynotis), lice (Felicola subrostratus) and gastrointestinal nematodes (Toxocara cati, Ancylostoma tubaeforme).
Estonian: ), aga ka lestade (Otodectes cynotis), täide (Felicola subrostratus) ja seedetrakti parasiitide (Toxocara cati, Ancylostoma tubaeforme) vastu.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each unit dose (pipette) delivers: Active substances: Felisecto Plus spot-on solution
Estonian: KVALITATIIVNE JA KVANTITATIIVNE KOOSTIS Iga üheannuseline pipett sisaldab: Toimeained: Felisecto Plusi täpilahus
English: Apply topically to the skin at the base of the neck in front of the shoulder blades.
Estonian: Manustada lokaalselt nahale looma kaela eesosas abaluude ees.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS PIPETTE
Estonian: MINIMAALSED ANDMED, MIS PEAVAD OLEMA VÄIKESEL VAHETUL SISEPAKENDIL
English: Containers and residual contents should be disposed of along with collected domestic refuse to avoid contamination of any water courses.
Estonian: Pakendid ja jäätmematerjal tuleb veekogudesse sattumise vältimiseks hävitada koos kodumajapidamises tekkivate jäätmetega.
English: Avoid contact between the product and your fingers.
Estonian: Vältida ravimi sattumist sõrmedele.
English: Translucent polypropylene unit dose pipettes individually packed in aluminium and aluminium/PVC blisters.
Estonian: Läbipaistvad polüpropüleenist üheannuselised pipetid, mis on üksikult pakendatud alumiiniumist ja alumiiniumist/PVC-st ümbristesse.
English: Strength and number of pipettes to be administered Felisecto Plus 15 mg/2.5 mg (yellow cap)
Estonian: Manustatavate pipettide tugevus ja arv Felisecto Plus 15 mg/2,5 mg (kollase korgiga)
English: Medicines should not be disposed of via wastewater.
Estonian: Kasutamata jäänud ravimeid ega jäätmematerjali ei tohi ära visata kanalisatsiooni kaudu.
English: >2.5-5 kg >5-10 kg selamectin/sarolaner
Estonian: ≤ 2,5 kg > 2,5-5 kg > 5-10 kg selamectin/sarolaner
English: - Prevention of heartworm disease caused by Dirofilaria immitis with monthly administration.
Estonian: - Dirofilaria immitis'e põhjustatud südameusstõve ravi igakuise manustamisega.
English: EXPIRY DATE EXP {month/year}
Estonian: KÕLBLIKKUSAEG EXP {kuu.aasta}
English: For cats with, or at risk from, mixed parasitic infestations by ticks and fleas, lice, mites, gastrointestinal nematodes or heartworm.
Estonian: Kassid, kellel on või kellel on risk saada parasiitide seganakkus, mille põhjustajaks on puugid, kirbud, täid, lestad, ümarussid või südameussid.
English: Part the hair at the base of the cat's neck in front of the shoulder blades to expose a small area of skin.
Estonian: Suruda karv looma kaela eesosas abaluude ees lahku ja paljastada väike nahapiirkond.
English: Holding the pipette upright, firmly depress the cap to puncture the applicator seal, then remove the cap.
Estonian: Hoides tuubi püstises asendis, suruda korki allapoole, et purustada aplikaatori kate, seejärel eemaldada kork.
English: In cats, selamectin and sarolaner are low clearance compounds with long half-life values, 12.5 days and 41.5 days respectively, following topical administration.
Estonian: Kassidel on lokaalse manustamise järel selamektiin ja sarolaner väikese kliirensi ning pika poolestusajaga (vastavalt 12,5 ja 41,5 päeva) ained.
English: Do not apply when the animal's hair coat is wet.
Estonian: Mitte manustada märja karvastikuga loomadele.
English: The product is available in packs of three pipettes (all pipette sizes).
Estonian: Toode on müügil kolme pipetiga (kõik suurused) pakendites.
English: Disruption of these receptors by sarolaner prevents the uptake of chloride ions by GABA and glutamate gated ion channels, thus resulting in increased nerve stimulation and death of the target parasite.
Estonian: Nende retseptorite töö häirimine hoiab ära klooriioonide sidumise GABA ja glutamaadi kanalitega, suurendades parasiidi närvistimulatsiooni ja viies selle surmani.
English: Keep treated animals away from fires and other sources of ignition for at least 30 minutes or until the hair coat is dry.
Estonian: Hoida loomi vähemalt 30 minutit pärast preparaadi manustamist või karvastiku kuivamiseni eemal lahtisest tulest või teistest süüteallikatest.
English: Sarolaner is active against adult fleas (Ctenocephalides spp.)
Estonian: Sarolaner on aktiivne täiskasvanud kirpude (Ctenocephalides spp.
English: Transient cosmetic effects may occur at the application site such as temporary clumping or spiking of the hair, greasiness or dry white deposits, which normally resolve within 24 hours after product application.
Estonian: Preparaadi manustamiskohal võivad esineda mööduvad kosmeetilised nähud, nagu karvade kokkukleepumine, rasvasus või vähese koguse valge pulbri ilmumine; need ilmingud kaovad harilikult 24 tunni jooksul.
English: Ectoparasites:
Estonian: Välisparasiidid:
English: The veterinary medicinal product has immediate and persistent acaricidal effect for 5 weeks against Ixodes ricinus and Ixodes hexagonus, and 4 weeks against Dermacentor reticulatus and Rhipicephalus sanguineus.
Estonian: Veterinaarravimil on kohene ja püsiv akaritsiidne toime 5 nädalat Ixodes ricinus'e ja Ixodes hexagonus'e puukide ja 4 nädalat Dermacentor reticulatus'e ja Rhipicephalus sanguineus'e puukide vastu.
English: For fleas, the onset of efficacy is within 24 hours for 5 weeks after product application.
Estonian: Kirpude puhul hakkab ravim mõjuma 24 tunni jooksul manustamisest ja toime kestab viis nädalat.
English: Marketing authorisation holder and manufacturer responsible for batch release:
Estonian: Müügiloa hoidja ja partii vabastamise eest vastutav tootja:
English: If significant ingestion occurs, transient gastrointestinal effects such as hypersalivation, emesis, soft faeces or reduced food consumption may be observed and should normally resolve without treatment.
Estonian: Märkimisväärse allaneelamise korral võivad esineda mööduvad seedetrakti häired, nagu hüpersalivatsioon, oksendamine, pehme väljaheide või vähenenud söömine; need mööduvad tavaliselt ilma ravita.
English: Selamectin is a semi-synthetic compound of the avermectin class.
Estonian: Selamektiin on poolsünteetiline avermektiinide rühma kuuluv aine.
English: Avoid eye contact including hand-to-eye-contact.
Estonian: Vältida kontakti silmadega, sealhulgas silmade puudutamist saastunud kätega.
English: In cats the primary route of selamectin elimination is in faeces and the majority is parent compound.
Estonian: Kassidel eritub selamektiin peamiselt väljaheidetega ja enamikus eritub lähteaine.
English: Sarolaner is an acaricide and insecticide belonging to the isoxazoline family.
Estonian: Sarolaner on isoksaliinide klassi kuuluv akaritsiid ja insektitsiid.
English: Cats ≤2.5 kg Cats >2.5-5 kg Cats >5-10 kg
Estonian: ≤ 2,5 kg kassid > 2,5-5 kg kassid > 5-10 kg kassid
English: Nematodes: - Treatment of adult roundworms (Toxocara cati) and adult intestinal hookworms (Ancylostoma tubaeforme).
Estonian: Nematoodid: - Täiskasvanud ümarusside (Toxocara cati) ja soolenugiliste (Ancylostoma tubaeforme) ravi.
English: METHOD AND ROUTE(S) OF ADMINISTRATION Spot-on use.
Estonian: MANUSTAMISVIIS JA -TEE(D) Täppmanustamine.
English: Selamectin may adversely affect aquatic organisms.
Estonian: Selamektiin võib olla ohtlik veeorganismidele.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE CARDBOARD BOX
Estonian: VÄLISPAKENDIL PEAVAD OLEMA JÄRGMISED ANDMED PAPPKARBIL
English: The veterinary medicinal product has immediate and persistent acaricidal effect for 5 weeks against Ixodes ricinus and Ixodes hexagonus, and 4 weeks against
Estonian: Veterinaarravimil on kohene ja püsiv akaritsiidne toime 5 nädalat Ixodes ricinus'e ja Ixodes hexagonus'e puukide ja 4 nädalat Dermacentor reticulatus'e ja
English: Ticks must attach to the host and commence feeding in order to be exposed to sarolaner.
Estonian: Sarolaneriga kokku puutumiseks peavad puugid kinnituma peremehele ja alustama toitumist.
English: Pipette content (ml)
Estonian: Pipeti sisu (ml)
English: This veterinary medicinal product is to be applied to the skin surface only.
Estonian: Preparaat on mõeldud ainult naha pinnale manustamiseks.
English: Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
Estonian: Mitte kasutada kassidel, kes põevad mingit lisahaigust, on kurtunud või alakaalulised.
English: This stops flea reproduction, breaks the flea lifecycle and may aid in the control of existing environmental flea infestations in areas to which the animal has access.
Estonian: See peatab kirpude paljunemise, katkestab nende elutsükli ja võib aidata kontrollida kirpude esinemist loomaga kokkupuutuvas keskkonnas.
English: STATEMENT OF THE ACTIVE SUBSTANCE(S) AND OTHER INGREDIENT(S) Each unit dose (pipette) delivers: Active substances: Felisecto Plus spot-on solution
Estonian: TOIMEAINETE JA ABIAINETE SISALDUS Iga üheannuseline pipett sisaldab: Toimeained: Felisecto Plusi täpilahus
English: After accidental ingestion of a full product dose, transient gastrointestinal effects such as salivation, soft faeces, emesis, and reduced food consumption may occur, however these should resolve without treatment.
Estonian: Juhuslikul kogu annuse allaneelamisel võivad tekkida mööduvad seedehäired, sealhulgas suurenenud süljeeritus, pehme väljaheide, oksendamine ja vähenenud toidutarbimine; need nähud mööduvad ravita.
English: For ear mite treatment, do not apply directly to the ear canal.
Estonian: Kuulmelestadest põhjustatud parasitoosi raviks mitte manustada otse kuulmekäiku.
English: Special precautions for storage
Estonian: SÄILITAMISE ERITINGIMUSED
English: Special precautions to be taken by the person administering the veterinary medicinal product to animals
Estonian: Ettevaatusabinõud veterinaarravimit loomale manustavale isikule Toote allaneelamine on kahjulik.
English: The primary target of action of sarolaner in insects and acarines is functional blockade of ligand-gated chloride channels (GABA-receptors and glutamate-receptors).
Estonian: Sarolaner mõjub putukatele ja lestadele nende ligand-sõltuvaid kloorikanaleid (GABA ja glutamaadi retseptoreid) blokeerides.
English: CONTENTS BY WEIGHT, BY VOLUME OR BY NUMBER OF DOSES 0.25 ml
Estonian: PAKENDI SISU KAALU, MAHU VÕI ANNUSTE ARVU JÄRGI
English: - Treatment of tick infestations.
Estonian: - Puuginakkuse ravi.
English: Sarolaner exhibits higher functional potency to block insect/acarine receptors compared to mammalian receptors.
Estonian: Sarolaneril on omadus imetajate retseptoritega võrreldes paremini blokeerida putukate/lestade retseptoreid.
English: Debris from selamectin-treated pets kills flea eggs and larvae not previously exposed to selamectin and thus may aid in the control of existing environmental flea infestations in areas to which the animal has access.
Estonian: Selamektiiniga ravitud loomadelt pärinev materjal tapab kirbumunad ja vastsed, mis ei olnud varem selamektiiniga kokku puutunud, aidates sellega kontrollida kirpude esinemist looma ümbritsevas keskkonnas.
English: SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF ANY
Estonian: ERINÕUDED ETTEVAATUSABINÕUDE OSAS KASUTAMATA JÄÄNUD PREPARAADI VÕI JÄÄTMETE, KUI NEID TEKIB, HÄVITAMISEL
English: Do not remove the pipette from the blister until ready to use.
Estonian: Eemaldage pipett ümbrisest vahetult enne kasutamist.
English: Treatment of roundworm and hookworm infections A single dose of the product should be administered.
Estonian: Ümarusside ja nugiliste põhjustatud infektsioonide ravi Manustatakse üks annus.
English: Dermacentor reticulatus and Rhipicephalus sanguineus.
Estonian: Rhipicephalus sanguineus'e puukide vastu.
English: Through its ovicidal and larvicidal action, the veterinary medicinal product may aid in the control of existing environmental flea infestations in areas to which the animal has access.
Estonian: Tänu mune ja vastseid hävitavale toimele võib ravim aidata kontrollida ka olemasolevat kirbunakkust kohas, kuhu loomal on juurdepääs.
English: Use of the veterinary medicinal product may result in mild and transient pruritus at the application site.
Estonian: Veterinaarravimi kasutamisel võib manustamiskohal täheldada kerget mööduvat ärritust.
English: This veterinary medicinal product is not effective against adult D. immitis.
Estonian: Preparaat ei toimi Dirofilaria immitis'e täiskasvanud vormide vastu.
English: DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION Spot-on use.
Estonian: ANNUSTAMINE LOOMALIIGITI, MANUSTAMISVIIS(ID) JA -MEETOD Täppmanustamine.
English: Sarolaner blocks GABA- and glutamate-gated chloride channels in the central nervous system of insects and acarines.
Estonian: Sarolaner blokeerib putukate ja lestade kesknärvisüsteemis olevaid GABA ja glutamaadiga seotud kloorikanaleid.
English: Pregnancy and lactation:
Estonian: Tiinus ja laktatsioon
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) 15 mg selamectin / 2.5 mg sarolaner 30 mg selamectin / 5 mg sarolaner 60 mg selamectin / 10 mg sarolaner
Estonian: TOIMEAINE(TE) SISALDUS 15 mg selamektiini / 2,5 mg sarolanerit 30 mg selamektiini / 5 mg sarolanerit 60 mg selamektiini / 10 mg sarolanerit
English: Butylated hydroxytoluene
Estonian: Butüülitud hüdroksütolueen Dipropüleenglükoolmonometüüleeter Isopropüülakohol
English: Total volume of unit dose (ml)
Estonian: Üksikannuse maht (ml)
English: Felisecto Plus 30 mg/5 mg (orange cap)
Estonian: Felisecto Plus 30 mg/5 mg
English: PACKAGE SIZE 3 pipettes 0.25 ml
Estonian: PAKENDI SUURUS(ED) 3 pipetti
English: Felisecto Plus >2.5-5 kg
Estonian: Felisecto Plus ≤ 2,5 kg Felisecto Plus > 2,5-5 kg Felisecto Plus > 5-10 kg
English: selamectin (mg)
Estonian: Selamektiin (mg)
English: Selamectin is active against adult fleas (Ctenocephalides spp.)
Estonian: Selamektiin on aktiivne täiskasvanud kirpude (Ctenocephalides spp.
English: The product is highly flammable.
Estonian: Veterinaarravim on väga kergsüttiv.
English: Specific pharmacovigilance requirements:
Estonian: MUUD TINGIMUSED JA NÕUDED MÜÜGILOALE Ravimiohutuse järelevalve nõuded:
English: Selamectin has adulticidal, ovicidal and larvicidal activity against fleas.
Estonian: Selamektiinil on täiskasvanud kirpude, kirbuvastsete ja munade vastane toime.
English: 4.9 Amounts to be administered and administration route Spot-on use.
Estonian: 4.9 Annustamine ja manustamisviis
English: The primary route of elimination for sarolaner is biliary elimination of parent sarolaner, with contributions by metabolic clearance.
Estonian: Sarolaner eritatakse peamiselt lähteainena sapiga, sellele aitab kaasa ka metaboolne kliirens.
English: Treatment schedule
Estonian: KEELUAEG
English: However, selamectin is considered safe for use in breeding, pregnant and lactating cats.
Estonian: Selamektiini kasutamine tiinetel, aretuses kasutatavatel ja lakteerivatel kassidel on tunnistatud ohutuks.
English: AUTHORISATION
Estonian: LISAINFO
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Felisecto Plus 15 mg/2.5 mg spot-on solution for cats ≤2.5 kg Felisecto Plus 30 mg/5 mg spot-on solution for cats >2.5-5 kg Felisecto Plus 60 mg/10 mg spot-on solution for cats >5-10 kg Selamectin/sarolaner
Estonian: VETERINAARRAVIMI NIMETUS Felisecto Plus 15 mg/2,5 mg täpilahus kassidele ≤ 2,5 kg Felisecto Plus 30 mg/5 mg täpilahus kassidele > 2,5-5 kg Felisecto Plus 60 mg/10 mg täpilahus kassidele > 5-10 kg Selamektiin/sarolaner
English: Mild to moderate alopecia at the application site, erythema and drooling have been uncommonly observed.
Estonian: Harvadel juhtudel on täheldatud ka kerget kuni mõõdukat alopeetsiat manustamiskohal, punetust ja suurenenud süljeeritust.
English: Spot-on solution.
Estonian: Täppmanustamine.
English: Treatment of biting lice A single dose of the product should be administered.
Estonian: Preparaadi äralakkumise vähendamiseks on tähtis manustada ravimit juhendi järgi.
English: PACKAGE LEAFLET: Felisecto Plus 15 mg/2.5 mg spot-on solution for cats ≤2.5 kg Felisecto Plus 30 mg/5 mg spot-on solution for cats >2.5-5 kg Felisecto Plus 60 mg/10 mg spot-on solution for cats >5-10 kg
Estonian: PAKENDI INFOLEHT Felisecto Plus, 15 mg/2,5 mg täpilahus kassidele ≤ 2,5 kg Felisecto Plus, 30 mg/5 mg täpilahus kassidele > 2,5-5 kg Felisecto Plus, 60 mg/10 mg täpilahus kassidele > 5-10 kg
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Felisecto Plus 15 mg/2.5 mg spot-on solution for cats ≤2.5 kg Felisecto Plus 30 mg/5 mg spot-on solution for cats >2.5-5 kg Felisecto Plus 60 mg/10 mg spot-on solution for cats >5-10 kg
Estonian: VETERINAARRAVIMI NIMETUS Felisecto Plus, 15 mg/2,5 mg täpilahus kassidele ≤ 2,5 kg Felisecto Plus, 30 mg/5 mg täpilahus kassidele > 2,5-5 kg Felisecto Plus, 60 mg/10 mg täpilahus kassidele > 5-10 kg
English: Pipettes with yellow caps contain 0.25 ml of product and deliver 15 mg selamectin and 2.5 mg sarolaner Pipettes with orange caps contain 0.5 ml of product and deliver 30 mg selamectin and 5 mg sarolaner Pipettes with green caps contain 1 ml of product and deliver 60 mg selamectin and 10 mg sarolaner
Estonian: Oranži korgiga pipetid sisaldavad 0,5 ml ravimit, sealhulgas 30 mg selamektiini ja 5 mg sarolanerit.
English: ≤2.5 kg
Estonian: 0,25 ml
English: PHARMACEUTICAL FORM Spot-on solution.
Estonian: RAVIMVORM Täpilahus.
English: - For the treatment and prevention of flea infestations (Ctenocephalides spp.).
Estonian: - Kirbunakkuse (Ctenocephalides spp.)
English: In addition, the company presented results from two other main studies.
Estonian: Ettevõte esitas ka kahe teise põhiuuringu andmed.
English: This summary was last updated in 01-2014.
Estonian: Kokkuvõtte viimane uuendus: 01-2014.
English: The usual dose is 10 mg once a day.
Estonian: Tavaline annus on 10 mg üks kord ööpäevas.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Brintellix on 18 December 2013.
Estonian: Euroopa Komisjon andis Brintellixi müügiloa, mis kehtib kogu Euroopa Liidu territooriumil, 18 detsembril 2013.
English: It is used to treat major depression in adults.
Estonian: Seda kasutatakse raske depressiooni raviks täiskasvanutel.
English: Side effects were usually mild or moderate, short-lasting and occurred in the first two weeks of treatment.
Estonian: Kõrvaltoimed olid enamasti kerged kuni mõõdukad ja lühiaegsed ning ilmnesid ravi esimesel kahel nädalal.
English: The full EPAR for Brintellix can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Estonian: Euroopa avaliku hindamisaruande täistekst Brintellixi kohta on ameti veebilehel: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: A risk management plan has been developed to ensure that Brintellix is used as safely as possible.
Estonian: Töötati välja riskijuhtimiskava, et tagada Brintellixi võimalikult ohutu kasutamine.
English: Supportive data from 52-week extensions of several of these studies suggested that the improvements that were seen were maintained longer-term.
Estonian: Mitme nimetatud uuringu 52nädalaste jätku-uuringute andmed näitasid, et uuringus täheldatud paranemine püsis pika aja vältel.
English: What measures are being taken to ensure the safe and effective use of Brintellix?
Estonian: Mis meetmed võetakse, et tagada Brintellixi ohutu ja efektiivne kasutamine?
English: The Agency's Committee for Medicinal Products for Human Use (CHMP) decided that Brintellix's benefits are greater than its risks and recommended that it be approved for use in the EU.
Estonian: Inimravimite komitee otsustas, et Brintellixi kasulikkus on suurem kui sellega kaasnevad riskid, ja soovitas ravimi kasutamise Euroopa Liidus heaks kiita.
English: Other information about Brintellix
Estonian: Muu teave Brintellixi kohta
English: Brintellix vortioxetine
Estonian: Brintellix vortioksetiin
English: Brintellix can only be obtained with a prescription and is available as tablets (5, 10, 15 and 20 mg) and oral drops (20 mg/ml).
Estonian: Brintellix on retseptiravim ja seda turustatakse tablettide (5 mg, 10 mg, 15 mg ja 20 mg) ja suukaudsete tilkadena (20 mg/ml).
English: What is Brintellix and what is it used for?
Estonian: Mis on Brintellix ja milleks seda kasutatakse?
English: Serotonin is a neurotransmitter, a chemical that transmits signals between nerve cells.
Estonian: Serotoniin on neuromediaator ehk keemiline aine, mis vahendab signaalide ülekannet ajurakkude vahel.
English: Because serotonin is involved in the control of mood, and can regulate the actions of other neurotransmitters that may be involved in depression and anxiety, these actions of vortioxetine are thought to result in its effect in improving depression.
Estonian: Et serotoniin osaleb meeleolu reguleerimises ning võib reguleerida ka teiste depressiooni ja ärevusega seotud neuromediaatorite toimet, siis arvatakse, et need vortioksetiini toimed leevendavadki depressiooni.
English: This is a summary of the European public assessment report (EPAR) for Brintellix.
Estonian: See on ravimi Brintellix Euroopa avaliku hindamisaruande kokkuvõte.
English: Effects on the gut such as nausea are more common in women than in men.
Estonian: Seedetrakti kõrvaltoimed, näiteks iiveldus, on naistel sagedamad kui meestel.
English: Treatment with Brintellix should continue for at least 6 months after the depressive symptoms have resolved.
Estonian: Ravi Brintellixiga peab pärast depressiooni sümptomite kadumist kestma veel vähemalt 6 kuud.
English: Although there was limited information about the use of doses above 10 mg daily in the elderly this was addressed in the product information.
Estonian: Et andmed 10 mg ületavate annuste kasutamise kohta eakatel patsientidel olid piiratud, mainiti seda ravimiteabes.
English: Patients 65 years of age and over should be started on a lower dose of 5 mg daily.
Estonian: 65-aastastel ja vanematel patsientidel on ravi algannus 5 mg ööpäevas.
English: Why is Brintellix approved?
Estonian: Miks Brintellix heaks kiideti?
English: In addition, vortioxetine blocks the action of the serotonin transporter, which is responsible for clearing serotonin from its sites of activity in the brain, thus increasing the activity of serotonin.
Estonian: Peale selle blokeerib vortioksetiin serotoniini transporteri toime, mis eemaldab serotoniini selle toimekohtadest ajus, tugevdades seeläbi serotoniini toimet.
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Brintellix, including the appropriate precautions to be followed by healthcare professionals and patients.
Estonian: Selle alusel lisati Brintellixi omaduste kokkuvõttesse ja pakendi infolehele ravimi ohutusteave, kus on ka tervishoiuspetsialistide ja patsientide võetavad meetmed.