FrancophonIA/ELRC3.0 huggingface dataset:
English: PACKAGE INSERT FOR INCLUSION WITH THE 7.5 % ORAL GEL SYRINGE PACKAGES
Estonian: PAKENDI INFOLEHT 7,5% PERORAALSE GEELI PAKENDILE
English: Name and address of the Manufacturing Authorisation Holder responsible for batch release
Estonian: TOOTMISLOA HOIDJA, KES VASTUTAB RAVIMIPARTII VABASTAMISE EEST
English: Do not use during the period of growth or in combination with nonsteroidal anti-inflammatory drugs (NSAIDs) in dogs with a history of seizures.
Estonian: Mitte kasutada kasvuperioodil ega koos mittesteroidsete põletikuvastaste ravimitega (NSAID-id) koertel, kellel on esinenud krampe.
English: 15 mg per kg bodyweight = 1 ml of gel per 5 kg bodyweight Read the package insert before use.
Estonian: 15 mg kg kehamassi kohta = 1 ml geeli 5 kg kehamassi kohta Enne kasutamist lugege pakendi infolehte.
English: When administered over a period of 30 days to healthy cats, Ibaflin oral gel produced vomiting/regurgitation and salivation at doses of 15 to 75 mg/kg.
Estonian: Ravimi manustamisel tervetele kassidele 30 päeva jooksul doosides alates 15 mg/kg kuni 75 mg/kg kehamassi kohta põhjustas Ibaflin oral gel oksendamist/sööda taasväljutamist ja süljevoolu.
English: IBAFLIN 3% ORAL GEL ADJUSTABLE MULTIDOSE SYRINGE
Estonian: Ibaflin 3% Oral Gel
English: The gel should therefore be administered at feeding time to ensure maximal bioavailability.
Estonian: Maksimaalse biosaadavuse tagamiseks peaks ravimit manustama toitmise ajal.
English: The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger (steps of 0.5 ml for the 15 ml syringe).
Estonian: Süstal tuleb tuleb reguleerida vastavalt arvestatud doosile, keerates doseerimisrõngas kolvil sobivasse asendisse (üks aste 15 ml süstlal võrdub 0,5 ml-ga ).
English: Special precautions to be taken by the person administering the product Persons with known hypersensitivity to quinolones should avoid contact with the veterinary medicinal product.
Estonian: Inimesed, kes on konoloonide suhtes ülitundlikud , peaksid kokkupuudet veterinaarravimiga vältima.
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Ibaflin 7.5% oral gel
Estonian: VETERINAARRAVIMI NIMETUS Ibaflin 7,5% peroraalne geel
English: PHARMACOLOGICAL PARTICULARS
Estonian: Farmakodünaamilised omadused
English: 15 mg per kg bodyweight = 1 ml of gel per 5 kg bodyweight
Estonian: 15 mg ühe kg kehakaalu kohta = 1 ml geeli 5 kg kehakaalu kohta.
English: Ibaflin gel is indicated in cats for treatment of the following conditions:
Estonian: Kassidele on Ibaflin geel näidustatud järgmiste haiguslike seisundite raviks:
English: After multiple oral administration, steady state is reached after the first or second dosing and no accumulation or induction of biotransformation enzymes occurs.
Estonian: Ravimi korduval peroraalsel manustamisel saavutatakse püsiv toime juba pärast esmast või teistkordset manustamist.
English: The safety of the veterinary medicinal product has not been established in lactating dog.
Estonian: Veterinaarravimi ohutust lakteerivatele koertele ei ole uuritud.
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) 75 mg of ibafloxacin per ml of gel
Estonian: TOIMEAINE(TE) KOGUS 1 ml geeli sisaldab ibafloksatsiini 75 mg
English: Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with the local requirements.
Estonian: Kasutamata veterinaarravimid või nende nende jäätmed tuleb hävitada vastavalt kohalikule seadusandlusele.
English: When administered orally at 75 mg/kg/day (five times the recommended dose) for a period of 90 days in dogs, ibafloxacin was well tolerated.
Estonian: Ravimi peroraalsel manustamisel koertele doosis 75 mg kg kehamassi kohta (viiekordne üledoos) 90 päeva jooksul oli ibafloksatsiin hästi talutav.
English: Antacids can interfere with gastro-intestinal absorption of quinolones.
Estonian: Happesuse alandajad võivad häirida kinoloonide imendumist seedekulglast.
English: Do not use in dogs with known quinolone hypersensitivity.
Estonian: Mitte kasutada koertel, kellel esineb ülitundlikkust kinoloonide suhtes.
English: IBAFLIN 7.5% ORAL GEL ADJUSTABLE MULTIDOSE SYRINGE
Estonian: Ibaflin 7,5% Oral Gel
English: CARTON BOX FOR 1 SYRINGE IBAFLIN 3% ORAL GEL / CARTON BOX FOR 5 SYRINGES IBAFLIN 3% ORAL GEL
Estonian: VÄLISPAKENDIL PEAVAD OLEMA JÄRGMISED ANDMED KARTONGKARP 1 SÜSTLAGA IBAFLIN 3% PERORAALNE GEEL / KARTONGKARP 5 SÜSTLAGA IBAFLIN 3% PERORAALNE GEEL
English: Carton box containing 1 adjustable pre-filled multidose syringe, containing 30 ml Ibaflin 7.5% oral gel.
Estonian: Kartongkarp sisaldab 1 reguleeritavat eeltäidetud süstalt sisaldusega 30 ml Ibaflin 7,5% peroraalset geeli.
English: Marketing Authorisation number(s) EU/2/00/022/09-12
Estonian: MÜÜGILOA NUMBER (NUMBRID) EU/2/00/022/09-12
English: B. CONDITIONS OF THE MARKETING AUTHORISATION INCLUDING
Estonian: B. MÜÜGILOA TINGIMUSED, SEALHULGAS HANKE- JA KASUTUSPIIRANGUD Retseptiravim
English: Active substance(s)
Estonian: Toimeaine(d):
English: For the majority of breeds, the use of ibafloxacin is contra-indicated in dogs less than 8 months of age and in giant breeds less than 18 months old.
Estonian: Enamikule koeratõugudele on ibafloksatsiini kasutamine vastunäidustatud kuni 8. elukuuni; suurtele tõugudele kuni 18. elukuuni.
English: ROUTE(S) OF ADMINISTRATION Oral use, 15 mg per kg bodyweight once daily (i.e. 0.5 ml of gel per kg body weight).
Estonian: Peroraalselt, 15 mg kg kehamassi kohta üks kord päevas (0,5 ml geeli kg kehamassi kohta).
English: METHOD AND ROUTE(S) OF ADMINISTRATION Oral use, 15 mg per kg bodyweight once daily.
Estonian: MANUSTAMISVIIS JA -TEE(D) Peroraalselt 15 mg kg kehamassi kohta päevas.
English: QUANTITY OF THE ACTIVE SUBSTANCE(S) 30 mg of ibafloxacin per ml of gel
Estonian: TOIMEAINE(TE) KOGUS 1 ml geeli sisaldab ibafloksatsiini 30 mg
English: 15 mg per kg bodyweight = 0.5 ml of gel per kg bodyweight
Estonian: 15 mg ühe kg kehakaalu kohta = 0,5 ml geeli ühe kg kehakaalu kohta.
English: For ibafloxacin (parent compound), MIC values ranging from 0.032 - 0.5 µg/ml are observed for canine isolates of E. coli, Staphylococcus spp.
Estonian: Täheldati, et koertelt isoleeritud E. coli, Staphylococcus spp., Proteus mirabilis suhtes kõigub ibafloksatsiini (algaine) MIK väärtus alates 0,032 µg/ml kuni 0,5 µg/ml.
English: 0.5 ml of gel per kg body weight
Estonian: 0,5 ml geeli kg kehamassi kohta
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Ibaflin 7.5% oral gel for dogs.
Estonian: VETERINAARRAVIMI NIMETUS Ibaflin 7,5% peroraalne geel koertele.
English: Ibaflin gel is indicated in dogs for the treatment of the following conditions:
Estonian: Koertele on Ibaflin geel näidustatud järgmiste haiguslike seisundite raviks:
English: For ibafloxacin (parent compound), MIC values ranging from 0.032 - 0.5 µg/ml are observed for canine isolates of E. coli, Staphylococcus spp., Proteus mirabilis, strains of Pasteurella spp.
Estonian: Täheldati, et koertelt isoleeritud E. coli, Staphylococcus spp., Proteus mirabilis suhtes kõigub ibafloksatsiini (algaine) MIK väärtus alates 0,032 µg/ml kuni 0,5 µg/ml
English: Ibaflin can be used during pregnancy.
Estonian: Ibaflini kasutamine tiinuse ajal on lubatud.
English: - Dermal infections (soft tissue infections - wounds, abscesses) caused by susceptible pathogens such as Staphylococcus spp., E. coli, Proteus spp.
Estonian: - Nahainfektsioonid (pehmete kudede nakkused - haavad, abstsessid), mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli, Proteus spp.
English: Excipients
Estonian: Tärklis
English: ROUTE(S) OF ADMINISTRATION Oral use, 15 mg per kg bodyweight once daily (i.e. 1 ml of gel per 5 kg body weight).
Estonian: Peroraalselt, 15 mg kg kehamassi kohta üks kord päevas (1 ml geeli 5 kg kehamassi kohta).
English: Marketing Authorisation number(s) EU/2/00/022/001-008
Estonian: MÜÜGILOA NUMBER (NUMBRID) EU/2/00/022/001-008
English: The Netherlands
Estonian: Austria
English: Oral use, 15 mg ibafloxacin/kg bodyweight once daily.
Estonian: Peroraalne manustamine, 15 mg ibafloksatsiini /kg kehamassi kohta päevas.
English: / Carton box containing 5 adjustable pre-filled multidose syringes, containing 30 ml Ibaflin 7.5% oral gel.
Estonian: Kartongkarp sisaldab 5 reguleeritavat eeltäidetud süstalt sisaldusega 30 ml Ibaflin 7,5% peroraalset geeli.
English: MARKETING AUTHORISATION NUMBER(S) EU/2/00/022/11
Estonian: MÜÜGILOA NUMBER (NUMBRID) EU/2/00/022/11
English: The main excretory route is via urine and faeces.
Estonian: Organismist väljutatakse ravim peamiselt uriini ja väljaheidetega.
English: Ibaflin 30 mg
Estonian: 30 ml
English: - Upper respiratory tract infections caused by susceptible pathogens such as Staphylococcus spp., E. coli, Klebsiella spp.
Estonian: - Ülemiste hingamisteede nakkused, mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli, Klebsiella spp.
English: Yeast
Estonian: Pärm
English: EXPIRY DATE (Month/year)
Estonian: Keeluaeg (-ajad)
English: Oral Gel
Estonian: Peroraalne geel
English: MARKETING AUTHORISATION NUMBER(S) EU/2/00/022/09
Estonian: MÜÜGILOA NUMBER (NUMBRID) EU/2/00/022/09
English: The overall absorption was higher in dogs and cats when administered with food.
Estonian: Imendumine oli parem ravimi manustamisel koos toiduga ja seda.nii kassidel kui koertel Seetõttu peaks maksimaalse biosaadavuse tagamiseks geeli manustama toitmise ajal.
English: After oral administration in cats, ibafloxacin is rapidly absorbed with maximum plasma levels observed at 1 hour when administered without food and 2 hours when administered with food.
Estonian: Maksimaalne plasma kontsentratsioon saavutatakse ilma toiduta manustamisel 1 tunni jooksul, koos toiduga manustamisel 2 tunni jooksul.
English: Intervet GesmbH.
Estonian: Intervet International B.V.
English: After multiple oral administration, steady state is reached after the first dosing and no accumulation occurs in dogs whereas modest accumulation is observed in cats.
Estonian: Koertel ei ilmne ravimi akumuleerumist, mõõdukat akumuleerumist on täheldatud kassidel.
English: Magnesium stearate
Estonian: Naatriumlaurüülsulfaat Ränidioksiid Magneesiumstearaat
English: Quinolones should not be used in combination with nonsteroidal anti-inflammatory drugs (NSAID) in dogs with a history of seizures.
Estonian: Mitte kasutada kinoloone koos mittesteroidsete põletikuvastaste ravimitega (NSAID-id) koertele, kellel on esinenud krampe.
English: After multiple oral administration, steady state is reached after the first dosing and no accumulation occurs in dogs.
Estonian: Ravimi korduval peroraalsel manustamisel saavutatakse püsiv plasmakontsentratsioon koertel juba pärast esmakordset manustamist.
English: INDICATIONS Ibaflin gel is indicated in dogs for the treatment of the following conditions: - Dermal infections (pyoderma - superficial and deep, wounds, abscesses) caused by susceptible pathogens such as Staphylococcus spp., E. coli and Proteus mirabilis.
Estonian: NÄIDUSTUS(ED) Koertele on Ibaflin geel näidustatud järgmiste haiguslike seisundite raviks: - Nahainfektsioonid (pindmine ja süvamine püoderma, haavad, abstsessid), mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli ja Proteus mirabilis´e poolt.
English: Veterinary medicinal product subject to prescription.
Estonian: Antud veterinaarravimit loomadele manustava isiku poolt rakendatavad spetsiaalsed ettevaatusabinõud
English: Dermal infections (pyoderma - superficial and deep, wounds, abscesses) caused by susceptible strains such as Staphylococci, E. coli, Proteus mirabilis.
Estonian: Nahainfektsioonid (püoderma - nii pindmine kui sügav, haavad, abstsessid), mis on põhjustatud stafülokokkide, E. coli, ja Proteus mirabilis`e poolt.
English: - Dermal infections (pyoderma - superficial and deep, wounds, abscesses) caused by susceptible pathogens such as Staphylococcus spp., E. coli and Proteus mirabilis.
Estonian: - Nahainfektsioonid (pindmine ja süvamine püoderma, haavad, abstsessid), mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli ja Proteus mirabilis´e poolt.
English: Ibaflin is indicated for the treatment of the following conditions in dogs: Dermal infections (pyoderma - superficial and deep, wounds, abscesses) caused by susceptible strains of Staphylococci, E. coli, and Proteus mirabilis.
Estonian: Koertele on Ibaflin geel näidustatud järgmiste haiguslike seisundite raviks: - Nahainfektsioonid (pindmine ja süvamine püoderma, haavad, abstsessid), mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli ja Proteus mirabilis´e poolt.
English: Do not use in combination with nonsteroidal anti-inflammatory drugs (NSAIDs) in dogs with a history of seizures.
Estonian: Mitte kasutada koos mittesteroidsete põletikuvastaste ravimitega (NSAID-id) koertele, kellel on esinenud krampe.
English: Respiratory tract infections (upper tract) caused by susceptible strains of Staphylococci, E. coli, and Klebsiella spp.
Estonian: Ülemiste hingamisteede nakkused, mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli, Klebsiella spp.
English: Acute, uncomplicated urinary tract infections, caused by susceptible strains of Staphylococci, Proteus spp., Enterobacter spp., E. coli and Klebsiella spp.
Estonian: Kuseteede ägedad komplitseerumata nakkused, mis on põhjustatud stafülokokkide, Proteus spp., Enterobacter spp., E. coli ja Klebsiella spp.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet of Ibaflin contains:
Estonian: Iga Ibaflin tablett sisaldab
English: Ibaflin gel is indicated in dogs for the treatment of the following conditions: - Dermal infections (pyoderma - superficial and deep, wounds, abscesses) caused by susceptible pathogens such as Staphylococcus spp., E. coli and Proteus mirabilis Ibaflin gel is indicated in cats for treatment of the following conditions: - Dermal infections (soft tissue infections - wounds, abscesses) caused by susceptible pathogens such as Staphylococcus spp., E. coli, Proteus spp.
Estonian: Kassidele on Ibaflin geel näidustatud järgmiste haiguslike seisundite raviks: - Nahainfektsioonid (pehmete kudede nakkused - haavad, abstsessid), mis on põhjustatud ibafloksatsiinile tundlike Staphylococcus spp., E. coli, Proteus spp.
English: However, a risk cannot be completely excluded.
Estonian: Riski ei saa aga täielikult välistada.
English: - Alcohol abuse.
Estonian: - Alkoholi kuritarvitamine.
English: Date of first authorisation: 18 August 2016
Estonian: Müügiloa esmase väljastamise kuupäev: 18 august 2016
English: You should see green plastic.
Estonian: Peaksite nägema rohelist plasti.
English: Use only once a week
Estonian: Kasutada ainult üks kord nädalas
English: Nordimet with food, drink and alcohol
Estonian: Nordimet koos toidu, joogi ja alkoholiga
English: Do not use if the date has passed.
Estonian: Ärge kasutage, kui tähtaeg on möödas.
English: 2132 WT Hoofddorp The Netherlands
Estonian: 2132 WT Hoofddorp Holland
English: 9) The injection lasts for a maximum of 10 seconds.
Estonian: 9) Süstimine kestab maksimaalselt 10 sekundit.
English: Component of a multipack, can't be sold separately
Estonian: Mitmikpakendi osa, ei saa eraldi müüa
English: 2) Sit or lie in a relaxed, comfortable position.
Estonian: 2) Istuge või lamage lõdvestunult, mugavas asendis.
English: Other medicines and Nordimet
Estonian: Muud ravimid ja Nordimet
English: The dose should be adjusted as follows:
Estonian: Annust tuleb kohandada järgmiselt:
English: Do not use Nordimet during pregnancy or if you are trying to become pregnant.
Estonian: Ärge kasutage Nordimet'i raseduse ajal või kui te üritate rasestuda.
English: It is important to tell your doctor that you are taking Nordimet.
Estonian: Oluline on öelda oma arstile, et te võtate Nordimet'i.
English: Healthcare professionals and patients should be clearly instructed.
Estonian: Tervishoiutöötajaid ja patsiente tuleb nõuetekohaselt teavitada.
English: SE-201 25 Malmo Sweden
Estonian: SE-201 25 Malmo Rootsi
English: This can lead to a loss of the medicine.
Estonian: See võib viia ravimi kaotuseni.
English: - Assessment of respiratory system.
Estonian: - Respiratoorse süsteemi hindamine.
English: You may see a small air bubble, this does not affect the injection and will not harm you.
Estonian: Te võite märgata väikseid õhumulle, see ei mõjuta süsti ega kahjusta teid.
English: - Decide where you are going to inject the medicine.
Estonian: - Otsustage, kuhu te ravimi süstite.
English: An overactive immune system has been linked to inflammatory diseases.
Estonian: Üliaktiivset immuunsüsteemi on seostatud põletikuliste haigustega.
English: The tests below must be conducted every week during the first two weeks, then every two weeks for the next month; afterwards, depending on leukocyte count and stability of the patient, at least once monthly during the next six months and at least every three months thereafter.
Estonian: Analüüse tuleb teha igal nädalal esimese kahe nädala jooksul, järgneval kuul iga kahe nädala järel; edaspidi sõltuvalt leukotsüütide arvust ja patsiendi seisundi stabiilsusest vähemalt üks kord kuus järgneva kuue kuu jooksul ja seejärel iga kolme kuu järel:
English: Pregnant health care personnel should not handle and/or administer methotrexate.
Estonian: Rasedad tervishoiutöötajad ei tohi metotreksaati käsitleda ja/või hallata.
English: However, your doctor may decide that you can learn how to inject Nordimet yourself.
Estonian: Samas võib arst otsustada, et võite õppida Nordimet'i ise süstima.
English: Therefore, it is very important that methotrexate is not given to pregnant patients or patients planning to become pregnant.
Estonian: Seetõttu on väga oluline, et metotreksaati ei kasutaks patsiendid, kes on rasedad või planeerivad rasestuda.
English: - Serious, acute or chronic infections such as tuberculosis and HIV.
Estonian: - Tõsised, ägedad või kroonilised infektsioonid, näiteks tuberkuloos ja HIV.
English: 11) Remove the needle by pulling it out straight.
Estonian: 11) Eemaldage nõel, tõmmates selle otse välja.
English: The printed package leaflet of the medicinal product must state the name and address of the manufacturer responsible for the release of the concerned batch.
Estonian: Ravimi trükitud pakendi infolehes peab olema vastava ravimipartii vabastamise eest vastutava tootja nimi ja aadress.
English: - Immunodeficiency.
Estonian: - Immuunpuudulikkus.
English: This is to make sure that the needle stays clean.
Estonian: See tagab, et nõel jääks puhtaks.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription and herbal or natural medicinal products.
Estonian: Teatage oma arstile või apteekrile, kui te võtate, olete hiljuti võtnud või kavatsete võtta, mis tahes muid ravimeid, sealhulgas ilma retseptita ostetud ravimid ja taimsed või looduslikud ravimid.
English: If you feel tired or dizzy, you should not drive or use machines.
Estonian: Kui tunnete väsimust või uimasust, ärge juhtige autot ega käsitsege masinaid.
English: You can now let go of the skin fold.
Estonian: Nüüd võite nahavoldi lahti lasta.
English: If not, use another pen.
Estonian: Kui ei, siis kasutage teist pen-süstlit.
English: It requires 30-60 seconds to be effective.
Estonian: Toime saabumiseks kulub 30…60 sekundit.
English: Teratogenicity - Reproductive risk
Estonian: Teratogeensus - reproduktiivne risk
English: In case of renal insufficiency, elimination is delayed significantly.
Estonian: Neerupuudulikkuse korral aeglustub eliminatsioon märkimisväärselt.
English: Nordimet is for subcutaneous use (see section 6.6.
Estonian: Nordimet on subkutaanseks kasutamiseks (vt lõik 6.6.
English: 2D barcode carrying the unique identifier included
Estonian: 2D-vöötkood, milles sisaldub ainulaadne identifikaator
English: If you are not sure what to do, talk to your doctor or nurse immediately.
Estonian: Kui te ei ole kindel, mida teha, rääkige kohe oma arsti või õega.
English: You may also have a chest X-ray.
Estonian: Teile võidakse teha ka rindkere röntgenuuring.
English: Do not try to inject yourself if you have not been trained on how to do so.
Estonian: Ärge püüdke ravimit ise süstida, kui te pole saanud koolitust, kuidas seda teha.
English: What Nordimet contains
Estonian: Mida Nordimet sisaldab
English: Note: the safety system allowing release of the safety shield, can only be activated when the syringe has been emptied by pressing the plunger all the way down.
Estonian: Märkus: ohutuskatte vabanemist võimaldav ohutussüsteem aktiveerub ainult siis, kui süstel on tühjendatud vajutades kolvi täiesti alla.
English: If you suspect that you have used too much Nordimet, tell your doctor or contact the nearest hospital immediately.
Estonian: Kui te kahtlustate, et olete kasutanud Nordimet'i liiga palju, rääkige sellest oma arstile või võtke ühendust lähima haiglaga.
English: If you wish to become pregnant you should consult your doctor, who may refer you for specialist advice before the planned start of treatment.
Estonian: Kui te soovite jääda rasedaks, peaksite konsulteerima oma arstiga, kes võib teid enne planeeritud ravi algust suunata spetsialisti konsultatsioonile.
English: Frequencies are defined using the following convention: very common (≥ 1/10) common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data).
Estonian: Esinemissageduse määratlemisel on kasutatud järgmist konventsiooni: väga sage (≥1/10), sage (≥ 1/100 kuni < 1/10), aeg-ajalt (≥ 1/1,000 kuni < 1/100), harv (≥ 1/10,000 kuni < 1/1,000), väga harv (< 1/10,000), teadmata (ei saa hinnata olemasolevate andmete alusel).
English: Children, adolescents and the elderly being treated with Nordimet should be kept under close medical surveillance to identify possible side effects as early as possible.
Estonian: Laste, noorukite ja eakate ravi Nordimet'iga peab toimuma pideva meditsiinilise järelevalve all, et avastada võimalikud kõrvaltoimed võimalikult vara.
English: You should not interrupt or discontinue Nordimet treatment before discussing with your doctor.
Estonian: Sa ei tohiks katkestada või lõpetada ravi Nordimet'iga eelnevalt arstiga nõu pidamata.
English: The doctor will calculate the dose required from the child's body surface area (m2), and the dose is expressed as mg/m
Estonian: Arst arvutab annuse lapse kehapinna ruutmeetri kohta (m2), ja annust väljendatakse mg/m
English: Make sure you can see the skin area you are going to inject.
Estonian: Veenduge, et näete naha pinda, kuhu kavatsete süstida.
English: If clinically indicated, exclude tuberculosis and hepatitis.
Estonian: Kliinilise kahtluse korral tuleb välistada tuberkuloos ja hepatiit.
English: Average terminal half-life is 6-7 hours and demonstrates considerable variation (3-17 hours).
Estonian: Poolväärtusaeg on keskmiselt 6...7 tundi ja varieerub märkimisväärselt (3...17 tundi).
English: Nordimet must not be used
Estonian: Nordimet'i ei tohi kasutada
English: Methotrexate may be genotoxic.
Estonian: Metotreksaat võib olla genotoksiline.
English: Do not use this medicine if you notice that the solution is not clear and contains particles.
Estonian: Ärge kasutage seda ravimit, kui märkate, et lahus ei ole läbipaistev ja sisaldab nähtavaid osakesi.
English: It must be injected once weekly and it is recommended to always inject Nordimet on the same day of the week.
Estonian: Süstitakse üks kord nädalas ja soovitav on süstida Nordimet'i alati samal päeval nädalas.
English: B-1420 Braine-l'Alleud Belgium
Estonian: B-1420 Braine-l'Alleud Belgia
English: - Severe renal impairment (creatinine clearance less than 30 ml/min) (see sections 4.2 and 4.4).
Estonian: - Raske neerukahjustus (kreatiniini kliirens vähem kui 30 ml/min) (vt lõigud 4.2 ja 4.4).
English: Patients must be instructed to report all signs and symptoms suggestive of infection.
Estonian: Patsiente tuleb juhendada teatama kõikidest infektsioonile viitavatest nähtudest ja sümptomitest.
English: Pulmonary diseases induced by methotrexate were not always completely reversible.
Estonian: Metotreksaadist põhjustatud kopsuhaigused ei ole alati täielikult pöörduvad.