FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients who completed the pivotal PATH study without relapse on 0.4 g/kg bw dose and initially received this dose in the extension study had a relapse rate of 5.6 % (1/18 patients).
Croatian: kod 0,2 g/kg i 196,1 dana (raspon: 1-330) u skupini 0,4 g/kg tt. Bolesnici koji su završili pivotalno PATH ispitivanje bez relapsa na dozu od 0,4 g/kg tt i početno su primili ovu dozu u nastavku ispitivanja, imali su relaps stopu od 5,6% (1/18 bolesnika).
English: • Flushing
Croatian: • Omaglica
English: The approximate percentage of IgG subclasses is as follows:
Croatian: Približan postotak IgG podvrste je kako slijedi: IgG1……….69%
English: Hizentra 200 mg/ml solution for subcutaneous injection human normal immunoglobulin (SCIg) For subcutaneous use only.
Croatian: Hizentra 200 mg/ml otopina za supkutanu injekciju ljudski normalni imunoglobulin (s.c.Ig) Samo za supkutanu primjenu.
English: Hizentra 200 mg/ml solution for subcutaneous injection in pre-filled syringe human normal immunoglobulin (SCIg) For subcutaneous use only.
Croatian: Hizentra 200 mg/ml otopina za supkutanu injekciju u napunjenoj štrcaljki ljudski normalni imunoglobulin (s.c.Ig) Samo za supkutanu primjenu.
English: United Kingdom CSL Behring UK Ltd. Tel: +44 (0)1444 447405
Croatian: Tel: +44 (0)1444 447405
English: Burning sensation
Croatian: Osjećaj pečenja
English: Magyarország CSL Behring Kft.
Croatian: United Kingdom CSL Behring UK Ltd.
English: Infusion rate
Croatian: Mjesto infuzije
English: You may reduce possible side effects if you infuse Hizentra slowly.
Croatian: Spora primjena infuzije Hizentre može smanjiti pojavu nuspojava.
English: OUTER BOX (pre-filled syringe)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU VANJSKA KUTIJA (napunjena štrcaljka)
English: CSL Behring GmbH D-35041 Marburg Germany
Croatian: D-35041 Marburg Njemačka
English: 3 Thoroughly wash and dry hands 4 Check Vials Visually inspect Hizentra for particles in the solution or discoloration as well as expiry date before administering Hizentra.
Croatian: Prije primjene Hizentre, otopinu treba vizualno pregledati na prisutnost vidljivih čestica ili promjenu boje, kao i rok valjanosti.
English: Sodium content Hizentra is essentially sodium free.
Croatian: Sadržaj natrija Hizentra sadrži zanemarive količine natrija.
English: 4 g / 20 ml
Croatian: 20 x 20 ml
English: If you get any side effects talk to your healthcare professional.
Croatian: - Ako primijetite bilo koju nuspojavu, potrebno je obavijestiti zdravstvenog radnika.
English: Tell your doctor or healthcare professional prior to treatment if you have an immunoglobulin type A (IgA) deficiency.
Croatian: Molimo obavijestite svog liječnika ili zdravstvenog radnika u slučaju ranijeg nepodnošenja bilo kojeg od navedenih sastojaka ► ako patite od hiperprolinemije (genetski poremećaj koji uzrokuje visoke razine aminokiseline prolina u krvi).
English: See section 4.
Croatian: Pogledajte dio 4. Što se nalazi u ovoj uputi:
English: Simulations with population-pharmacokinetic models in the PATH study suggest that a comparable IgG exposure (Cmax, AUC0-14days, Cmin, 14 days) is achieved when the double weekly Hizentra dose is administered every two weeks in the CIDP subjects.
Croatian: (3,06) g/l u skupini na 0,2 g/kg tt. Simulacije s populacijskim farmakokinetičkim modelima u ispitivanju PATH upućuju na to da je usporediva izloženost IgG-u (Cmax, AUC0-14 dana, Cmin, 14 dana)
English: 1 g/5 ml 2 g/10 ml
Croatian: 1 g / 5 ml
English: No paediatric-specific dose adjustments were necessary to achieve the desired serum IgG levels.
Croatian: Za dostizanje željene razine IgG u serumu nije bilo potrebno posebno prilagođavanje pedijatrijske doze.
English: Weight in kilograms
Croatian: Težina u kilogramima
English: Ask your pharmacist how to throw away the medicines you no longer use.
Croatian: Pitajte svog ljekarnika kako baciti lijekove koje više ne koristite.
English: Different organs are affected at different ages.
Croatian: Različiti organi su zahvaćeni u različitoj dobi.
English: After opening do not store above 25°C.
Croatian: Nakon otvaranja ne čuvati na temperaturi iznad 25°C.
English: Do not increase or decrease the amount of medicine without your doctor's approval.
Croatian: Nemojte povećavati ili smanjivati količinu lijeka bez odobrenja svog liječnika.
English: Examine your skin while taking this medicine.
Croatian: Pregledavajte svoju kožu tijekom uzimanja ovog lijeka.
English: This will help lessen the chance of loss of eyesight.
Croatian: To će smanjiti šansu za gubitak vida.
English: The entire amount of the mixture should be eaten.
Croatian: Mora se pojesti cjelokupna količina smjese.
English: The recommended dose for you or your child will depend on your or your child's age and weight.
Croatian: Preporučena doza za Vas ili Vaše dijete ovisi o Vašoj dobi i težini ili dobi i težini Vašeg djeteta.
English: The potential risk for humans is unknown.
Croatian: Nije poznat potencijalni rizik u ljudi.
English: Date of latest renewal: 26 July 2018
Croatian: Datum posljednje obnove odobrenja: 26 Srpanj 2018
English: You may become drowsy.
Croatian: Možete postati omamljeni.
English: It is important to take these supplements exactly as instructed.
Croatian: Važno je uzimati te dodatke točno kako su Vas uputili.
English: Discard the open bottle and use a new bottle.
Croatian: Bacite otvorenu bocu i upotrijebite novu.
English: The Safety Checklist should highlight the following:
Croatian: Popis za provjeru sigurnosti treba istaknuti sljedeće:
English: You should not use this medicine if you are pregnant, particularly during the first trimester.
Croatian: Ne smijete uzimati ovaj lijek ako ste trudni, osobito tijekom prvog tromjesečja.
English: Recommended dose in mg Every 12 hours*
Croatian: Preporučena doza u mg Svakih 12 sati*
English: This is a condition where there is high pressure in the fluid around the brain.
Croatian: To je stanje u kojem je visok pritisak tekućine oko mozga.
English: These mainly involve the gastrointestinal and central nervous systems.
Croatian: One uglavnom uključuju gastrointestinalni i središnji živčani sustav.
English: Take this medicine two times a day, every 12 hours.
Croatian: Uzimajte ovaj lijek dva puta dnevno, svakih 12 sati.
English: Do not double the dose.
Croatian: Ne uzimajte dvostruku dozu.
English: Tell your doctor if you have these symptoms.
Croatian: Obratite se svom liječniku ako imate te simptome.
English: Do not take this medicine if the foil seal has been open for more than 30 days.
Croatian: Nemojte uzimati ovaj lijek ako je zaštitna folija zatvarača otvorena duže od 30 dana.
English: Method of administration You should take this medicine only by mouth.
Croatian: Način primjene Ovaj lijek smijete uzimati samo kroz usta.
English: PROCYSBI with food and drink
Croatian: PROCYSBI s hranom i pićem
English: Patients with poor tolerability
Croatian: Bolesnici sa slabijom podnošljivosti
English: Patients on dialysis or post-transplantation
Croatian: Bolesnici na dijalizi ili nakon transplantacije
English: The consequence of this for the clinical use of the drug is unknown.
Croatian: Nije poznata posljedica toga na kliničku uporabu lijeka.
English: Your doctor will monitor you for this.
Croatian: Vaš liječnik će Vas pratiti radi toga.
English: Warnings and precautions Talk to your doctor or pharmacist before taking PROCYSBI.
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku ili ljekarniku prije nego uzmete PROCYSBI.
English: The terminal half-life of cysteamine bitartrate is approximately 4 hours.
Croatian: Terminalni poluvijek cisteaminhidrogentartarata iznosi približno 4 sata.
English: The education pack is aimed at strengthening awareness of important identified and potential risks as well as appropriate patient selection, the need for dose titration and patient monitoring.
Croatian: Cilj edukativnog paketa je ojačati svijest o važnosti identificiranih i potencijalnih rizika kao i o odgovarajućem odabiru bolesnika, o potrebi za titracijom doze i nadzoru bolesnika.
English: When starting therapy, you should not drive, use machines, or engage in other dangerous activities until you know how the medicine affects you.
Croatian: Pri započinjanju liječenja ne smijete voziti, upravljati strojevima niti obavljati nikakve druge opasne aktivnosti sve dok ne znate kako lijek djeluje na Vas.
English: Central Nervous System (CNS)
Croatian: Središnji živčani sustav (SŽS)
English: As a precaution, unusual abdominal symptoms or changes in abdominal symptoms should be medically assessed to exclude the possibility of fibrosing colonopathy.
Croatian: Kao mjera opreza, neobični abdominalni simptomi ili promjene abdominalnih simptoma moraju se medicinski procijeniti kako bi se isključila mogućnost fibrozirajuće kolonopatije.
English: When these reactions appear at the initiation of cysteamine therapy, temporary suspension and gradual reintroduction of treatment may be effective in improving tolerance.
Croatian: Kad se ove reakcije pojave na početku liječenja cisteaminom, privremeni prestanak i postupno ponovno uvođenje liječenja mogu biti učinkoviti u poboljšanju podnošljivosti.
English: Measurement timing: PROCYSBI should be administered every 12 hours.
Croatian: Vrijeme mjerenja: PROCYSBI treba primjenjivati svakih 12 sati.
English: The frequency of adverse reactions is defined using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000) and not known (cannot be estimated from available data).
Croatian: Učestalost nuspojava definirana je sukladno sljedećoj konvenciji: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000) i nepoznato (ne može se procijeniti iz dostupnih podataka).
English: Do not give gastro-resistant hard capsules to children under 6 years of age because they may not be able to swallow them and they may choke.
Croatian: Nemojte davati tvrde želučanootporne kapsule djeci mlađoj od 6 godina jer ih ona možda neće moći progutati i mogu se ugušiti.
English: Two cases of nephrotic syndrome have been reported within 6 months of starting therapy with progressive recovery after treatment discontinuation.
Croatian: Prijavljena su dva slučaja nefrotskog sindroma unutar 6 mjeseci od početka liječenja s progresivnim oporavkom nakon prekida liječenja.
English: If you are allergic to penicillamine.
Croatian: Ako ste alergični na penicilamin.
English: Newly diagnosed adult patients
Croatian: Novodijagnosticirani odrasli bolesnici
English: Do not use this medicine if you are breastfeeding (see section 2 under “Do not use PROCYSBI”).
Croatian: Nemojte uzimati ovaj lijek ako dojite (pogledajte dio 2. pod ,,Nemojte uzimati PROCYSBI“).
English: Therefore, cysteamine bitartrate should not be used during pregnancy, particularly during the first trimester, unless clearly necessary (see section 4.4).
Croatian: Stoga se cisteaminhidrogentartarat ne smije primjenjivati tijekom trudnoće, osobito tijekom prvog tromjesečja, osim ako to nije izričito potrebno (vidjeti dio 4.4).
English: Do not take PROCYSBI:
Croatian: Nemojte uzimati PROCYSBI:
English: Thirty-nine (39) patients were included in the final primary per protocol efficacy analysis.
Croatian: Trideset devet (39) ispitanika je uključeno u finalnu primarnu analizu djelotvornosti prema planu ispitivanja.
English: Keep the container tightly closed in order to protect from light and moisture.
Croatian: Spremnik čuvati čvrsto zatvoren radi zaštite od svjetlosti i vlage.
English: Talk to your doctor if you have any unusual stomach symptoms or changes in stomach symptoms.
Croatian: Obratite se svom liječniku ako imate bilo kakve neobične želučane simptome ili promjene želučanih simptoma.
English: If you missed a dose of medicine, you should take it as soon as possible.
Croatian: Ako ste propustili dozu lijeka, morate ju uzeti što prije.
English: Report any changes to your doctor.
Croatian: Obavijestite svog liječnika o svim promjenama.
English: If several doses of the supplements are missed or weakness or drowsiness develops, call your doctor for instructions.
Croatian: Ako ste izostavili nekoliko doza nadomjestaka ili se razvije slabost ili omamljenost, nazovite svog liječnika za upute.
English: Since some of these side effects are serious, ask your doctor to explain their warning signs.
Croatian: Obzirom da su neke od ovih nuspojava ozbiljne, pitajte svog liječnika da Vam objasni znakove koji upozoravaju na njih.
English: Your doctor will monitor you with eye examinations to find and treat this problem early.
Croatian: Vaš liječnik će Vas nadzirati u očnim pregledima kako bi rano ustanovio i liječio taj problem.
English: Your doctor will monitor you for these problems.
Croatian: Vaš liječnik će Vas pratiti za te probleme.
English: Do not crush or chew capsules or capsule contents.
Croatian: Nemojte drobiti niti žvakati kapsule ili njihov sadržaj.
English: A white plastic bottle contains 60 capsules.
Croatian: Bijela plastična boca sadrži 60 kapsula.
English: What PROCYSBI is and what it is used for
Croatian: Što je PROCYSBI i za što se koristi
English: Consult your child's doctor for complete directions.
Croatian: Posavjetujte se sa svojim liječnikom za cjelovite upute.
English: Experience has occasionally shown that some forms of cysteamine are less well tolerated (i.e. leading to more adverse events) when patients are on dialysis.
Croatian: Iskustvo je pokazalo da se povremeno pojedini oblici cisteamina slabije podnose (tj. dovode do više štetnih događaja) kad su bolesnici na dijalizi.
English: If such symptoms develop, tell your doctor who will adjust your dose.
Croatian: Ako se razviju takvi simptomi, obratite se svom liječniku koji će prilagoditi Vašu dozu.
English: If a dose is missed, it should be taken as soon as possible.
Croatian: Ako se doza propusti, mora se uzeti što prije.
English: CYP2A6 and CYP3A4 were not involved in the metabolism of cysteamine bitartrate under the experimental conditions.
Croatian: CYP2A6 i CYP3A4 nisu uključeni u metabolizam cisteaminhidrogentartarata u eksperimentalnim uvjetima.
English: The relative bioavailability is about 125% as compared to immediate-release cysteamine.
Croatian: Relativna bioraspoloživost je oko 125% u usporedbi s cisteaminom s trenutnim oslobađanjem.
English: Skin rash: Tell the doctor right away if you get a skin rash.
Croatian: Kožni osip: Odmah se javite liječniku ako dobijete kožni osip.
English: If the rash is severe, your doctor may discontinue cysteamine treatment.
Croatian: Ako je osip težak, Vaš liječnik može prekinuti liječenje cisteaminom.
English: Physicians should remain alert for signs of ulceration and bleeding and should inform patients and/or guardians about the signs and symptoms of serious GI toxicity and what steps to take if they occur.
Croatian: Liječnici moraju pripaziti na znakove ulceracija i krvarenja te trebaju obavijestiti bolesnike i/ili skrbnike o znakovima i simptomima ozbiljne GI toksičnosti te koje korake poduzeti ako se pojave.
English: Open Date:
Croatian: Datum otvaranja:
English: Your doctor will routinely monitor your blood counts and liver function.
Croatian: Vaš liječnik će rutinski pratiti Vaše krvnu sliku i jetrenu funkciju.
English: If you are allergic to cysteamine (also known as mercaptamine) or any of the other ingredients of this medicine (listed in section 6).
Croatian: Ako ste alergični na cisteamin (poznat i kao merkaptamin) ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: At this dose, weight gain and survival of the offspring during lactation was also reduced.
Croatian: Pri toj je dozi bilo smanjeno dobivanje na težini i preživljavanje potomaka tijekom laktacije.
English: In clinical studies with healthy volunteers, the most frequent adverse reactions were very common GI symptoms (16%) and occurred primarily as single episodes that were mild or moderate in severity.
Croatian: U kliničkim ispitivanjima sa zdravim dobrovoljcima najčešće nuspojave su bili vrlo uobičajeni GI simptomi (16%) i pojavili su se primarno kao samostalne epizode koje su bile blage ili umjerene težine.
English: The effect on pregnancy of untreated cystinosis is also unknown.
Croatian: Učinak neliječene cistinoze na trudnoću također nije poznat.
English: No specific antidote is known.
Croatian: Nije poznat specifični protulijek.
English: Women of child-bearing potential should be advised to use an adequate method of contraception during the course of treatment;
Croatian: Ženama koje mogu zatrudnjeti mora se savjetovati da koriste odgovarajuću metodu kontracepcije tijekom liječenja;
English: Should overdosing occur, the respiratory and cardiovascular systems should be supported appropriately.
Croatian: Ukoliko dođe do predoziranja, mora se omogućiti odgovarajuća potpora dišnog i srčanožilnog sustava.
English: This medicine may cause some drowsiness.
Croatian: Ovaj lijek može uzrokovati omamljenost.
English: For at least 1 hour before and 1 hour after taking PROCYSBI try to avoid meals, which are rich in fat or proteins as well as any food or liquid that could decrease the acidity in your stomach, like milk or yogurt.
Croatian: Najmanje 1 sat prije i 1 sat poslije uzimanja lijeka PROCYSBI pokušajte izbjegavati obroke bogate mastima ili proteinima, kao i svaku hranu ili tekućinu koja može smanjiti kiselost u želucu, poput mlijeka ili jogurta.
English: Uncommon: Leukopenia
Croatian: Manje često: Leukopenija
English: Newly diagnosed adult patients should be started on 1/6 to 1/4 of the targeted maintenance dose of PROCYSBI.
Croatian: Novodijagnosticirani odrasli bolesnici moraju započeti s 1/6 do 1/4 ciljne doze održavanja lijeka PROCYSBI.
English: If CNS symptoms develop, the patient should be carefully evaluated and the dose adjusted as necessary.
Croatian: Ako se razviju simptomi SŽS-a, bolesnik se mora pažljivo procijeniti i doza se mora po potrebi prilagoditi.
English: These tests must be obtained 12.5 hours after the evening dose the day before, and therefore 30 minutes after the following morning dose is given.
Croatian: Te pretrage moraju se provesti 12,5 sati nakon večernje doze prethodnog dana i stoga 30 minuta nakon što se primijeni iduća jutarnja doza.
English: A white plastic bottle contains 250 capsules.
Croatian: Bijela plastična boca sadrži 250 kapsula.
English: Cysteamine is the simplest stable aminothiol and a degradation product of the amino acid cysteine.
Croatian: Cisteamin je najjednostavniji stabilni aminotiol i proizvod razgradnje aminokiseline cisteina.
English: The elimination of unchanged cysteamine in the urine has been shown to range between 0.3% and 1.7% of the total daily dose in four patients; the bulk of cysteamine is excreted as sulphate.
Croatian: Eliminacija nepromijenjenog cisteamina urinom dokazana je u rasponu između 0,3% i 1,7% ukupne dnevne doze kod četiri ispitanika; glavnina cisteamina se izlučuje u obliku sulfata.
English: Forty-three (43) patients were randomized; twenty-seven (27) children (ages 6 to 12 years old), fifteen (15) adolescents (ages 12 to 21 years old) and one (1) adult with cystinosis and with native kidney function based on an estimated Glomerular Filtration Rate (GFR) (corrected for body surface area) > 30 mL/minute/1.73 m2
Croatian: Četrdeset tri (43) ispitanika je nasumično raspodijeljeno u skupine; dvadeset sedmero (27) djece (starosti od 6 do 12 godina), petnaest (15) adolescenata (starosti od 12 do 21 godine) i jedan (1) odrasli s cistinozom i nativnom bubrežnom funkcijom na temelju procijenjene brzine glomerularne filtracije (GFR) (korigirane za površinu tijela) > 30 ml/minuti/1,73 m2.
English: In some cases, these skin lesions were associated with skin striae and bone lesions first seen during an X-ray examination.
Croatian: U nekim slučajevima te su kožne lezije povezane sa strijama i lezijama kostiju koje su prvo uočene rendgenskim pregledom.
English: Patients should not engage in potentially hazardous activities until the effects of cysteamine on mental performance are known (see section 4.7).
Croatian: Bolesnici ne smiju obavljati potencijalno opasne aktivnosti sve dok nisu poznati učinci cisteamina na mentalnu sposobnost (vidjeti dio 4.7).
English: Physicians should routinely monitor the skin and bones of patients receiving cysteamine.
Croatian: Liječnici moraju rutinski pregledavati kožu i kosti bolesnika koji primaju cisteamin.
English: There is no adequate data from the use of cysteamine in pregnant women.
Croatian: Ne postoje odgovarajući podaci o primjeni cisteamina u trudnica.
English: Of those forty-three (43) patients, two (2) siblings withdrew at the end of the first crossover period, due to a prior planned surgery in one (1) of them; forty-one (41) patients completed the protocol.
Croatian: Od tih četrdeset tri (43) ispitanika, dva (2) srodnika su se povukla iz ispitivanja na kraju prvog ukriženog razdoblja, zbog prethodno planirane operacije kod jednog (1) od njih; četrdeset jedan (41) ispitanik je završio plan ispitivanja.
English: Cysteamine bitartrate should not be administered with food rich in fat or proteins, or with frozen food like ice-cream.
Croatian: Cisteaminhidrogentartarat se ne smije primjenjivati uz hranu bogatu mastima ili proteinima, ili uz smrznutu hranu kao što je sladoled.
English: - Your medical treatment may include, in addition to cysteamine, one or more supplements to replace important electrolytes lost through the kidneys.
Croatian: - Vaše liječenje može uključivati, uz cisteamin, jedan ili više nadomjestaka kako bi se nadomjestili važni elektroliti koji se gube kroz bubrege.
English: •Guidance on appropriate patient selection and dose titration.
Croatian: • Smjernice o odgovarajućem odabiru bolesnika i titraciji doze.
English: Your doctor will routinely monitor your skin and bones and reduce or stop your treatment if needed (see section 4).
Croatian: Vaš liječnik će rutinski pratiti Vašu kožu i kosti te po potrebi smanjiti dozu ili prekinuti liječenje (pogledajte dio 4.).
English: Studies in animals have shown reproductive toxicity, including teratogenesis (see section 5.3).
Croatian: Ispitivanja na životinjama pokazala su reproduktivnu toksičnost, uključujući teratogenezu (vidjeti dio 5.3).
English: When starting therapy, patients should not engage in potentially hazardous activities until the effects of the medicinal product on each individual are known.
Croatian: Na početku liječenja, bolesnici ne smiju obavljati potencijalno opasne aktivnosti sve dok nisu poznati učinci lijeka na pojedinca.
English: Since oral cysteamine doesn't prevent deposits of cystine crystals in the eye, you should continue taking cysteamine eye drops as prescribed by your doctor.
Croatian: Kako oralni cisteamin ne sprečava odlaganje kristala cistina u oku, morate i dalje nastaviti uzimati cisteaminske kapi za oči kako Vam je propisao Vaš liječnik.
English: The in vitro plasma protein binding of cysteamine, primarily to albumin, is approximately 54% and independent of plasma drug concentration over the therapeutic range.
Croatian: Vezanje cisteamina na proteine plazme in vitro, primarno na albumin, iznosi približno 54% i neovisno je koncentraciji lijeka u plazmi unutar terapijskog raspona.
English: PROCYSBI is a medicine that reacts with cystine to decrease its level within the cells.
Croatian: PROCYSBI je lijek koji reagira s cistinom kako bi smanjio njegovu razinu unutar stanica.
English: An overdose of cysteamine may cause progressive lethargy.
Croatian: Predoziranje cisteaminom može uzrokovati progresivnu letargiju.
English: If you are a woman planning a pregnancy or become pregnant, seek immediate advice from your doctor about stopping therapy with this medicine as continued treatment may be harmful to the unborn baby.
Croatian: Ako planirate trudnoću ili zatrudnite, odmah potražite savjet svog liječnika o prekidu liječenja ovim lijekom jer nastavak može naškoditi nerođenom djetetu.
English: -0.21 ± 0.14; -0.48 to 0.06; <0.001
Croatian: -0,21 ± 0,14; -0,48 do 0,06; <0,001
English: Co-administration with electrolyte and mineral replacement
Croatian: Istovremena primjena s nadomjescima elektrolita i minerala
English: If you take more PROCYSBI than you should
Croatian: Ako uzmete više lijeka PROCYSBI nego što ste trebali