FrancophonIA/ELRC3.0 huggingface dataset:
English: Adults and adolescents (from 12 years and older) The recommended dose is 125 mg every 6 hours.
Croatian: Novorođenčad, dojenčad i djeca mlađa od 12 godina Preporučena doza vankomicina je 10 mg/kg peroralno svakih 6 sati tijekom 10 dana.
English: This age group may need blood tests for controlling vancomycin levels in blood.
Croatian: Razine vankomicina u krvi u takve djece će stoga možda biti potrebno kontrolirati.
English: [For parenteral formulations authorised for oral use, the indication should be as follows:] Oral administration
Croatian: [Za parenteralne formulacije odobrene za peroralnu primjenu navesti kako slijedi:] Peroralna primjena
English: Possible side effects [This section should read as follows:]
Croatian: [Ovaj dio treba glasiti:] [na sljedeće odlomke se treba osvrnuti u ovom dijelu:]
English: except Clostridium innocuum
Croatian: Clostridium spp. osim Clostridium innocuum Eubacterium spp.
English: The recommended vancomycin dose is 10 mg/kg orally every 6 hours for 10 days.
Croatian: Preporučena doza je 125 mg svakih 6 sati.
English: Common side effects (may affect up to 1 in 10 people): - Fall in blood pressure - Breathlessness, noisy breathing (a high pitched sound resulting from obstructed air flow in the upper airway) - Rash and inflammation of the lining of the mouth, itching, itching rash, hives
Croatian: - Nedostatak zraka, piskutavo disanje (visoki zvuk koji nastaje zbog začepljenog protoka zraka u gornjem dišnom putu) - Osip i upala sluznice usta, svrbež, osip koji svrbi, koprivnjača
English: Monitoring of vancomycin serum concentrations
Croatian: Kako primjenjivati Vankomicin
English: - Cardiac arrest
Croatian: Prijavljivanje nuspojava
English: Susceptible
Croatian: Osjetljivi
English: Treatment duration
Croatian: Postupak primjene
English: This summary was last updated in 08-2014.
Croatian: Sažetak je posljednji put ažuriran u 08. 2014.
English: The full EPAR for Zoledronic acid Teva can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Croatian: Cjeloviti EPAR za zoledronatnu kiselinu Teva nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: It is available as a concentrate (4 mg/5 ml) to be used to make a solution for infusion (drip) into a vein, and as a solution for infusion (4 mg/100 ml).
Croatian: Dostupan je kao koncentrat (4 mg/5 ml) za pripremuotopine za infuziju (drip) u venu i kao otopina za infuziju (4 mg/100 ml).
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Zoledronic acid Teva.
Croatian: Objašnjava kako je Odbor za lijekove za primjenu kod ljudi (CHMP) ocijenio lijek da bi donio svoje mišljenje u korist izdavanja odobrenja za stavljanje lijeka u promet i svoje preporuke u vezi s uvjetima za uporabu zoledronatne kiseline Teva.
English: It is not recommended for patients with severe kidney problems.
Croatian: Ne preporuča se za bolesnike s teškim oštećenjem bubrega.
English: Patients with tumours can have high levels of calcium in their blood, released from the bones.
Croatian: Bolesnici s tumorima mogu imati visoke razine kalcija u krvi, koji se otpušta iz kostiju.
English: Because Zoledronic acid Teva is a generic medicine, its benefits and risks are taken as being the same as the reference medicine's.
Croatian: Budući da je zoledronatna kiselina Teva generički lijek, smatra se da su njezine koristi i rizici isti kao i oni referentnog lijeka.
English: This means that Zoledronic acid Teva is similar to a ‘reference medicine' already authorised in the European Union (EU) called Zometa.
Croatian: To znači da je zoledronatna kiselina Teva sličan "referentnom lijeku” koji je već odobren u Europskoj uniji pod nazivom Zometa.
English: By preventing the breakdown of bones, Zoledronic acid Teva also helps to reduce the amount of calcium released into the blood.
Croatian: Sprječavajući razgradnju kostiju, zoledronatna kiselina Teva također pomaže u smanjenju količine kalcija koji se ispušta u krv.
English: For more information about treatment with Zoledronic acid Teva, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Croatian: Više informacija o terapiji Zoledronatnom kiselinom Teva pročitajte u uputi o lijeku (također dio EPAR-a), ili se obratite svom liječniku ili ljekarniku
English: The usual dose of Zoledronic acid Teva is one infusion of 4 mg over at least 15 minutes.
Croatian: Uobičajena doza zoledronatne kiseline Teva je jedna infuzija od 4 mg koja se uzima tijekom 15 minuta.
English: This is a summary of the European public assessment report (EPAR) for Zoledronic acid Teva.
Croatian: Ovo je sažetak europskoga javnog izvješća o ocjeni dokumentacije (EPAR)o zoledronatnoj kiselini Teva.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Zoledronic acid Teva on 16 August 2012.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje je za zoledronatnu kiselinu Teva na snazi u Europskoj uniji od 16. kolovoza 2012.
English: No additional studies were needed as Zoledronic acid Teva is a generic medicine that is given by infusion and contains the same active substance as the reference medicine, Zometa.
Croatian: Nisu bila potrebna dodatna ispitivanja jer je zoledronatna kiselina Teva generički lijek koji se daje infuzijom i sadrži istu djelatnu tvar kao i referentni lijek, Zometa.
English: Zoledronic acid Teva must only be used by a doctor who has experience in the use of this type of medicine given into a vein.
Croatian: Zoledronatnu kiselinu Teva smije koristiti samo liječnik koji je iskusan u primjeni ovog tipa lijeka u venu.
English: Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Zoledronic acid Teva, including the appropriate precautions to be followed by healthcare professionals and patients.
Croatian: Na temelju tog plana, u sažetku opisa svojstava lijeka kao i u uputi o lijeku za lijek zoledronatna kiselina Teva nalaze se sigurnosne informacije, uključujući odgovarajuće mjere opreza kojih se zdravstveni djelatnici i bolesnici trebaju pridržavati.
English: Zoledronic acid Teva can also be used to treat the hypercalcaemia caused by tumours.
Croatian: Zoledronatna kiselina Teva može se također koristiti za liječenje hiperkalkemije uzrokovane tumorima.
English: What measures are being taken to ensure the safe and effective use of Zoledronic acid Teva?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena zoledronatne kiseline Teva?
English: The CHMP concluded that, in accordance with EU requirements, Zoledronic acid Teva has been shown to be comparable to Zometa.
Croatian: CHMP je odlučio kako je u skladu s zahtjevimaEU-a, dokazano da je zoledronatna kiselina Teva usporediva s lijekom Zometa.
English: What are the benefits and risks of Zoledronic acid Teva?
Croatian: Koje su koristi i rizici zoledronatne kiseline Teva?
English: Zoledronic acid Teva is a ‘generic medicine'.
Croatian: Zoledronatna kiselina Teva je „generički lijek”.
English: A risk management plan has been developed to ensure that Zoledronic acid Teva is used as safely as possible.
Croatian: Pripremljen je plan upravljanja rizikom kako bi se osigurala što sigurnija primjena zoledronatne kiseline Teva.
English: The reduction of bone loss helps to make bones less likely to break, which is useful in preventing fractures in cancer patients with bone metastases.
Croatian: Smanjenje gubitka koštanog tkiva pospješuje prevenciju pucanja kostiju, što je korisno u prevenciji fraktura u bolesnika oboljelih od raka s metastazama u kostima.
English: Other information about Zoledronic acid Teva
Croatian: Ostale informacije o zoledronatnoj kiselini Teva
English: This includes fractures (breaks in the bone), spinal compression (when the spinal cord is compressed by the bone), bone disorders needing radiotherapy (treatment with radiation) or surgery, and hypercalcaemia (high levels of calcium in the blood).
Croatian: Zoledronatna kiselina Teva koristi se za prevenciju koštanih komplikacija u odraslih bolesnika s uznapredovalim rakom koji je zahvatio kost, što uključuje frakture (pucanje kosti), spinalnu kompresiju (kada kost komprimira kralježničku moždinu), koštane poremećaje koji zahtijevaju radioterapiju (liječenje zračenjem) ili kirurški zahvat i hiperkalkemiju (visoke razine kalcija u tijelu).
English: The active substance in Zoledronic acid Teva, zoledronic acid, is a bisphosphonate.
Croatian: Djelatna tvar zoledronatne kiseline Teva, zoledronatna kiselina, je bisfosfonat.
English: The Committee recommended that Zoledronic acid Teva be given marketing authorisation.
Croatian: Odbor je preporučio izdavanje odobrenja za stavljanje u promet zoledronatne kiseline Teva
English: Zoledronic acid Teva is a medicine that contains the active substance zoledronic acid.
Croatian: Zoledronatna kiselina Teva je lijek koji sadrži djelatnu tvar zoledronatnu kiselinu.
English: It stops the action of the osteoclasts, the cells in the body that are involved in breaking down the bone tissue.
Croatian: Zaustavlja djelovanje osteoklasta, stanica u tijelu koje su uključene u razgradnju koštanog tkiva što, omogućava manji gubitak koštanog tkiva.
English: Zoledronic acid Teva zoledronic acid
Croatian: Zoledronatna kiselina Teva zoledronatna kiselina
English: When used to prevent bone complications, the infusion can be repeated every three to four weeks, and patients should also take supplements of calcium and vitamin D. A lower dose is recommended for patients with bone metastases (when cancer has spread to the bone) if they have mild to moderate problems with their kidneys.
Croatian: Kada se koristi za prevenciju koštanih komplikacija, infuzija se može ponoviti svaka tri do četiri tjedna, a bolesnici moraju također uzimati dodatke kalcija i vitamina D.
English: Why has Zoledronic acid Teva been approved?
Croatian: Zašto je Zoledronatna kiselina Teva odobrena?
English: Therefore, the CHMP's view was that, as for Zometa, the benefit outweighs the identified risk.
Croatian: Stoga je stav CHMP-a kako koristi nadmašuju utvrđene rizike, kao i kod lijeka Zometa.
English: What is Zoledronic acid Teva?
Croatian: Što je zoledronatna kiselina Teva?
English: How is Zoledronic acid Teva used?
Croatian: Kako se zoledronatna kiselina Teva koristi?
English: What is Zoledronic acid Teva used for?
Croatian: Za što se Zoledronatna kiselina Teva koristi?
English: How has Zoledronic acid Teva been studied?
Croatian: Kako je zoledronatna kiselina Teva ispitivana?
English: How does Zoledronic acid Teva work?
Croatian: Kako djeluje zoledronatna kiselina Teva?
English: Invented name Strength Pharmaceutical Form
Croatian: Doza Farmaceutski oblik
English: EU Number
Croatian: EMA broj postupka Broj (EU) odobrenja
English: You may need medical help.
Croatian: Možda vam je potrebna medicinska pomoć.
English: This means you should:
Croatian: To znači da biste trebali:
English: How much to take
Croatian: Koliko uzeti
English: This is because it may harm your unborn baby.
Croatian: To je zato jer može naštetiti vašem nerođenom djetetu.
English: • wear clothing that covers your head, arms and legs
Croatian: • nositi odjeću koja pokriva glavu, ruke i noge
English: België/Belgique/Belgien, България, Česká republika, Danmark, Eesti, Ελλάδα, Hrvatska, Ísland, Κύπρος, Latvija, Lietuva, Luxembourg/Luxemburg, Magyarország, Malta, Norge, Polska, Portugal, România, Slovenija, Slovenská republika,
Croatian: België/Belgique/Belgien, България, Česká republika, Danmark, Eesti, Ελλάδα, Hrvatska, Ísland, Κύπρος, Latvija, Lietuva, Luxembourg/Luxemburg, Magyarország, Malta, Norge, Polska, Portugal, România, Slovenija, Slovenská republika, Suomi/Finland, Sverige:
English: Take care in direct sunlight
Croatian: Budite oprezni na izravnoj sunčevoj svjetlosti.
English: Median overall survival was not achieved in this population.
Croatian: Medijan ukupnog preživljenja nije postignut u ovoj populaciji.
English: The results should be interpreted with caution due to the limited representation of some subgroup phenotypes.
Croatian: Rezultate je potrebno oprezno interpretirati zbog ograničene zastupljenosti nekih fenotipskih podskupina.
English: • It is important to keep taking Rubraca every day - as long as your doctor prescribes it for you.
Croatian: • Važno je svakoga dana uzimati lijek Rubraca - sve dok Vam ga liječnik propisuje.
English: • Talk to your doctor or pharmacist about the most effective methods of contraception.
Croatian: • Razgovarajte sa svojim liječnikom ili ljekarnikom o najučinkovitijim metodama kontracepcije.
English: • Do not stop taking this medicine without talking to your doctor first.
Croatian: • Nemojte prestati uzimati lijek bez prethodnog razgovora sa svojim liječnikom.
English: Primary Efficacy N=106
Croatian: Primarni ishod djelotvornosti n=106
English: • Take the tablets once in the morning and once in the evening, approximately 12 hours apart.
Croatian: • Uzmite tablete jednom ujutro i jednom uvečer uz razmak od otprilike 12 sati.
English: Patients, n
Croatian: Bolesnice, n
English: See section 5.2.
Croatian: Vidjeti dio 5.2.
English: A potential risk cannot be ruled out based on the safety margin observed.
Croatian: Potencijalni rizik ne može se isključiti na temelju uočenih granica sigurnosti.
English: See section 4 for more information.
Croatian: Vidjeti dio 4 za više informacija.
English: • You can take the tablets with or without food.
Croatian: • Možete uzeti tablete sa ili bez hrane.
English: Age, race, and body weight
Croatian: Dob, rasa i tjelesna težina
English: Then take your next dose at the usual time.
Croatian: Zatim uzmite svoju sljedeću dozu u uobičajeno vrijeme.
English: An analysis of progression-free survival (PFS) was also performed.
Croatian: Također je provedena analiza preživljenja bez progresije (progression-free survival, PFS).
English: Rucaparib Placebo
Croatian: Rukaparib Placebo
English: Treatment was continued until disease progression or unacceptable toxicity.
Croatian: Liječenje je nastavljeno do progresije bolesti ili neprihvatljive toksičnosti.
English: Steady state was achieved after 1 week of dosing.
Croatian: Stanje dinamičke ravnoteže postignuto je nakon 1 tjedna doziranja.
English: The doses should be taken approximately 12 hours apart.
Croatian: Doze je potrebno uzimati u razmaku od otprilike 12 sati.
English: This means you take a total of 1,200 mg each day.
Croatian: To znači da ukupno uzimate 1200 mg svakoga dana.
English: (< 1/10,000), not known (cannot be estimated from the available data).
Croatian: 1/1000); vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
English: NA (21.7-NA)
Croatian: NP (21,7-NA)
English: Take care if you feel tired or feel sick (nauseous).
Croatian: Budite oprezni ako se osjećate umorno ili imate mučninu.
English: The food effect on PK was not considered clinically significant.
Croatian: Utjecaj hrane na PK nije smatran klinički značajnim.
English: If you take more Rubraca than you should
Croatian: Ako uzmete više lijeka Rubraca nego što ste trebali
English: If you have certain side effects your doctor may recommend a lower dose, or temporarily stop your treatment.
Croatian: Ako imate određene nuspojave, vaš liječnik može preporučiti nižu dozu ili privremeno prekinuti vaše liječenje.
English: Tell your doctor straight away if you notice any of the following side effects - you may need urgent medical treatment:
Croatian: Odmah obavijestite svog liječnika ako primijetite bilo koju od sljedećih nuspojava - možda će Vam biti potrebno hitno medicinsko liječenje:
English: • keep out of direct sunlight and not use sunbeds while you are taking Rubraca
Croatian: • držati se dalje od izravne sunčeve svjetlosti i ne koristiti solarije dok uzimate lijek Rubraca
English: Symptoms you should be aware of
Croatian: Simptomi na koje trebate obratiti pažnju:
English: • if you are allergic to rucaparib or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na rukaparib ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: Your doctor may also do weekly tests, if you have low blood cell counts for a long time.
Croatian: Vaš liječnik može također obavljati pretrage svakog tjedna ako dulje vrijeme imate nizak broj krvnih stanica.
English: Your doctor or nurse will perform blood tests to check your blood cell-counts:
Croatian: Vaš liječnik ili medicinska sestra obavit će pretrage krvi kako bi provjerili broj Vaših krvnih stanica:
English: There are limited clinical data in patients aged 75 or over.
Croatian: Postoje ograničeni podaci u bolesnica u dobi od 75 godina i starijih.
English: These may be signs and symptoms that Rubraca is affecting your stomach.
Croatian: To mogu biti znakovi i simptomi da Rubraca utječe na vaš želudac.
English: Pharmacokinetics in specific populations
Croatian: Farmakokinetika u posebnim populacijama
English: At the time of the analysis of PFS, OS data were not mature (with 22% of events).
Croatian: U vrijeme analize PFS-a, OS podaci nisu bili potpuni (uz 22 %
English: Censoring N (%)
Croatian: Cenzurirani n (%)
English: Talc (E553b)
Croatian: talk (E553b)
English: • Rubraca is not recommended during pregnancy.
Croatian: • Rubraca se ne preporučuje tijekom trudnoće.
English: • use a sunscreen and lip balm with a sun protection factor (SPF) of 50 or higher.
Croatian: • koristiti kremu za sunčanje i balzam za usne sa zaštitnim faktorom (SPF) 50 ili višim.
English: These reactions are manageable with routine medical treatment and/or dose adjustment for more severe cases.
Croatian: Te se reakcije mogu zbrinjavati rutinskim medicinskim liječenjem i/ili prilagodbom doze u težim slučajevima.
English: Platinum Sensitive N=79
Croatian: Osjetljiv na platinu n=79
English: It is important to proactively manage these events to avoid prolonged or more severe events of nausea/vomiting which have the potential to lead to complications such as dehydration or hospitalisation.
Croatian: Važno je proaktivno zbrinjavati ove događaje kako bi se izbjegli dugotrajni ili teži slučajevi mučnine/povraćanja koji mogu potencijalno dovesti do komplikacija kao što je dehidracija ili hospitalizacija.
English: (95% CI)
Croatian: (95 %-tni CI)
English: ITT populationa
Croatian: ITT populacijaa
English: Pregnant women should be informed of the potential risk to a foetus.
Croatian: Trudne žene moraju se informirati o potencijalnom riziku za fetus.
English: The only serious adverse reaction occurring in > 2% of patients was anaemia (5%).
Croatian: Jedina ozbiljna nuspojava koja se pojavila u > 2 % bolesnica bila je anemija (5 %).
English: Patients with changes (mutations) in genes called BRCA are at risk of developing a number of types of cancer.
Croatian: Bolesnice s promjenama (mutacijama) na genima koji se nazivaju BRCA imaju rizik od razvoja brojnih vrsta raka.
English: Mechanism of action and pharmacodynamics effects
Croatian: Mehanizam djelovanja i farmakodinamički učinci
English: Rubraca is supplied in plastic bottles.
Croatian: Rubraca dolazi u plastičnim bocama.
English: A total of 32% of patients were in complete response (CR) to their most recent therapy.
Croatian: Ukupno 32 % bolesnica postiglo je potpun odgovor (CR) na zadnju terapiju.
English: Contents of the pack and other information What Rubraca contains
Croatian: Sadržaj pakiranja i druge informacije Što Rubraca sadrži
English: • pain in the stomach
Croatian: • bol u trbuhu
English: Your doctor may test your bone marrow to check for any problems.
Croatian: Vaš liječnik može testirati vašu koštanu srž kako bi provjerio ima li nekakvih problema.
English: In the event of suspected overdose, physicians should follow general supportive measures and should treat symptomatically.
Croatian: U slučaju sumnje na predoziranje, liječnici trebaju slijediti opće suportivne mjere i provoditi simptomatsko liječenje.
English: Efficacy results from all patients treated are summarized in Table 5.
Croatian: Rezultati djelotvornosti od svih liječenih bolesnica sažeto su prikazani u Tablici 5.
English: Complete response % Partial response %
Croatian: Djelomični odgovor %
English: Four (5.1%) of 79 platinum sensitive patients overall had progressive disease as best response.
Croatian: Četiri (5,1 %) od 79 bolesnica s rakom osjetljivim na platinu ukupno je imalo progresivnu bolest kao najbolji odgovor.
English: The signs and symptoms of low blood cell counts include fever, infection, bruising or bleeding.
Croatian: Znakovi i simptomi niskog broja krvnih stanica uključuju vrućicu, infekciju, pojavu modrica ili krvarenja.
English: Therefore, use in this patient population is not recommended.
Croatian: Stoga se ne preporučuje primjena u ovoj populaciji bolesnica.
English: BRCA status based on a local test was known for some patients at the time of enrollment.
Croatian: BRCA status na temelju lokalnog testa bio je poznat za neke bolesnice u vrijeme uključivanja.
English: No events met Hy's Law criteria for drug-induced liver injury.
Croatian: Nijedan događaj nije ispunjavao kriterije Hyevog zakona za ozljedu jetre izazvanu lijekovima.
English: The absolute oral bioavailability at 600 mg has not been determined.
Croatian: Apsolutna oralna bioraspoloživost kod 600 mg nije utvrđena.
English: It is used after the cancer has responded to previous chemotherapy treatments.
Croatian: Koristi se nakon što je rak odgovorio na prethodno liječenje kemoterapijom.
English: Date of first authorisation: 24 May 2018 Date of latest renewal: 13 March 2019
Croatian: Datum posljednje obnove odobrenja: 13. ožujka 2019.
English: Following repeated twice daily dosing, the accumulation based on AUC ranged from 3.5 to 6.2 fold.
Croatian: Nakon ponovljenog doziranja uz primjenu dva puta dnevno, akumulacija na temelju AUC-a bila je u rasponu od 3,5- do 6,2-struke.
English: Pharmacotherapeutic group: Other antineoplastic agents, ATC code: L01XX55
Croatian: Farmakoterapijska skupina: ostali antineoplastici, ATK oznaka: L01XX55
English: For the platinum-refractory population (N=7), there were no responders.
Croatian: Za populaciju s rakom refraktornim na platinu (N=7), nije bilo ispitanica s odgovorom.
English: Grade 4 reactions require treatment modification (see Table 2).
Croatian: Reakcije 4. stupnja zahtijevaju modifikaciju liječenja (vidjeti Tablicu 2).
English: HDPE bottle, with a polypropylene (PP) induction seal closure, containing 60 tablets.
Croatian: HDPE boca, s polipropilenskim (PP) zatvaračem koja sadrži 60 tableta.
English: • Do not take a double dose to make up for a forgotten dose.
Croatian: • Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu tabletu.
English: Rucaparib may only be used in patients with severe renal impairment if the potential benefit outweighs the risk.
Croatian: Rukaparib se može koristiti u bolesnica s teškim oštećenjem funkcije bubrega samo ako potencijalna korist nadmašuje rizik.
English: These increases in serum creatinine were clinically asymptomatic.
Croatian: Te povišene vrijednosti kreatinina u serumu bile su klinički asimptomatske.
English: Other minor metabolites accounted for 13.8% of the radioactivity in plasma.
Croatian: Ostali manji metaboliti bili su odgovorni za 13,8 % radioaktivnosti u plazmi.
English: These events occurred within the first few weeks of treatment with rucaparib, were reversible, and were rarely associated with increases in bilirubin.
Croatian: Ti događaji dogodili su se unutar prvih nekoliko tjedana liječenja rukaparibom, bili su reverzibilni i rijetko povezani s povišenim vrijednostima bilirubina.
English: They may stop treatment with Rubraca until your blood cell counts improve.
Croatian: Može prekinuti liječenje lijekom Rubraca sve dok Vam se ne poboljša broj krvnih stanica.
English: Always take this medicine exactly as your doctor, pharmacist or nurse has told you.
Croatian: Uvijek uzmite ovaj lijek točno onako kako Vam je rekao liječnik, ljekarnik ili medicinska sestra.
English: • every month during treatment with Rubraca
Croatian: • svakog mjeseca tijekom liječenja lijekom Rubraca