FrancophonIA/ELRC3.0 huggingface dataset:
English: Clearance and volume of distribution were related to body weight by an allometric model with exponents of 0.433 and 1, respectively: as body weight increased from 10 to 60 kg, apparent oral clearance increased from 2.60 to 5.65 L/hr and apparent volume of distribution increased from 32.0 to 191.8 L. As a result, elimination half-life increased from 8.5hr (for 10 kg) to 23.5 hr (for 60 kg).
Slovenian: Očistek in volumen porazdelitve sta bila povezana s telesno maso z alometričnim modelom z eksponentoma 0,433 oziroma 1: ko se je telesna masa večala od 10 do 60 kg, se je navidezni peroralni očistek povečal z 2,60 na 5,65 l/uro, navidezni volumen porazdelitve pa se je povečal z 32,0 na 191,8 l. Zato se je razpolovna doba izločanja povečala z 8,5 ur (za 10 kg) na 23,5 ur (za 60 kg).
English: If your child forgets to take Diacomit
Slovenian: Če vaš otrok pozabi vzeti zdravilo Diacomit
English: Co-administration with CYP3A4 substrates with a narrow therapeutic index should be avoided due to the markedly increased risk of severe adverse reactions.
Slovenian: Sočasnemu dajanju substratov CYP3A4 z ozkim terapevtskim indeksom se je treba izogibati zaradi zelo povečanega tveganja za hude neželene učinke.
English: The potential for metabolic interaction between stiripentol and valproate is considered modest and thus, no modification of valproate dosage should be needed when stiripentol is added, except for clinical safety reasons.
Slovenian: Možnost presnovne interakcije med stiripentolom in valproatom se šteje za majhno, zato sprememba odmerjanja valproata po dodatku stiripentola ni potrebna razen zaradi klinične varnosti.
English: Dose adjustments of other antiepileptics used in combination with stiripentol
Slovenian: Prilagoditev odmerkov drugih zdravil proti epilepsiji, ki se uporabljajo sočasno s stiripentolom
English: • if your child has kidney or liver problems.
Slovenian: • če ima vaš otrok težave z ledvicami ali jetri,
English: It is recommended that if a switch of formulations is required this is done under clinical supervision, in case of problems with tolerability (see section 5.2).
Slovenian: Če je treba farmacevtski obliki zamenjati, je priporočeno, da se to stori pod zdravniškim nadzorom zaradi morebitnih težav s toleranco (glejte poglavje 5.2).
English: The capsules should not be chewed.
Slovenian: Kapsul ne sme žvečiti.
English: In the pivotal studies, when the use of stiripentol was initiated, the daily dose of clobazam was 0.5 mg/kg/day usually administered in divided doses, twice daily.
Slovenian: V ključnih študijah je bil ob uvedbi stiripentola dnevni odmerek klobazama 0,5 mg/kg/dan, običajno razdeljen v odmerka dvakrat dnevno.
English: - Cisapride, halofantrine, pimozide, quinidine, bepridil Increased risk of cardiac arrhythmias and torsades de pointes/wave burst arrhythmia in particular.
Slovenian: - Cisaprid, halofantrin, pimozid, kinidin, bepridil Povečano tveganje srčnih aritmij in zlasti pojava torsades de pointes/aritmije s porušitvijo valov.
English: Paediatric population pharmacokinetic study
Slovenian: Farmakokinetična študija na pediatrični populaciji
English: Clinical monitoring of plasma levels of other anticonvulsants when combined with stiripentol with possible dose adjustments is recommended.
Slovenian: Priporočeno je klinično spremljanje plazemskih ravni drugih antikonvulzivov, če se dajejo sočasno s stiripentolom, z možnostjo prilagoditve odmerkov.
English: The main metabolic processes are demethylenation and glucuronidation, although precise identification of the enzymes involved has not yet been achieved.
Slovenian: Glavni presnovni proces je demetilacija in glukuronidacija, vendar encimov, ki sodelujejo pri presnovi, še niso natančno določili.
English: Your child should not take a double dose to make up for a forgotten individual dose.
Slovenian: Vaš otrok ne sme vzeti dvojnega odmerka, če je pozabil vzeti prejšnji odmerek.
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Slovenian: Če vam je zdravnik povedal, da ne prenašate nekaterih sladkorjev, se posvetujte z njim, preden vzamete to zdravilo.
English: In this younger group of patients, adjunctive therapy with stiripentol should only be started when the diagnosis of SMEI has been clinically confirmed (see section 5.1).
Slovenian: V tej skupini mlajših bolnikov se lahko dodatno zdravljenje s stiripentolom začne šele, ko je diagnoza SMEI klinično potrjena (glejte poglavje 5.1).
English: In the pivotal studies in the event of gastrointestinal adverse reactions such as loss of appetite, loss of weight, the daily dose of valproate was reduced by around 30% every week.
Slovenian: V ključnih študijah so ob pojavu gastrointestinalnih neželenih učinkov, kot na primer izguba apetita, izguba telesne mase, dnevni odmerek valproata znižali za približno 30 % tedensko.
English: PHARMACEUTICAL FORM Powder for oral suspension Pale pink crystalline powder
Slovenian: Prašek za peroralno suspenzijo Bledo rožnat kristaličen prašek
English: The sachet formulation has a slightly higher Cmax than the capsules and thus the formulations are not bioequivalent.
Slovenian: Prašek za peroralno suspenzijo v vrečici ima nekoliko višji Cmax kot kapsule, zato farmacevtski obliki nista bioekvivalentni.
English: Unless otherwise clinically indicated, liver function should be checked every 6 months.
Slovenian: Če ni drugih kliničnih indikacij, je treba jetrno funkcijo preveriti vsakih 6 mesecev.
English: Relative bioavailability between the capsules and powder for oral suspension in sachet formulations has been studied in healthy male volunteers after a 1,000 mg single oral administration.
Slovenian: Relativna biološka uporabnost kapsul v primerjavi s praškom za peroralno suspenzijo v vrečici je bila predmet študije pri zdravih prostovoljcih moškega spola, ki so prejeli enkraten peroralni odmerek 1000 mg.
English: Responders were defined as having more than 50% reduction in the frequency of clonic (or tonicclonic) seizures during the second month of the double-blind period compared with baseline.
Slovenian: Kot odziv so šteli najmanj 50 % znižanje pogostnosti kloničnih (ali tonično-kloničnih) napadov v drugem mesecu dvojno slepega dela raziskave v primerjavi z izhodiščnim obdobjem.
English: Stiripentol is extensively metabolized, 13 different metabolites having been found in urine.
Slovenian: Stiripentol se obsežno presnavlja; v urinu so odkrili 13 različnih presnovkov.
English: phenobarbital, primidone, phenytoin, carbamazepine, diazepam.
Slovenian: fenobarbital, primidon, fenitoin, karbamazepin, diazepam.
English: Carbamazepine, phenytoin and phenobarbital
Slovenian: Karbamazepin, fenitoin in fenobarbital
English: Your child must NOT take Diacomit
Slovenian: Vaš otrok NE sme jemati zdravila Diacomit
English: A population pharmacokinetic study was conducted in 35 children with Dravet Syndrome treated with stiripentol and two substances not known to affect stiripentol pharmacokinetics, valproate and clobazam.
Slovenian: Populacijska farmakokinetična študija je bila opravljena pri 35 otrocih z Dravetovim sindromom, ki se zdravijo s stiripentolom ter valproatom in klobazamom, pri katerih pa vpliv na farmakokinetiko stiripentola ni znan.
English: Treatment should be continued for as long as efficacy is observed.
Slovenian: Z zdravljenjem nadaljujte, dokler opažate učinke.
English: Diplomat Business Centre, office 102 Sector 1, 010991 Bucharest Romania
Slovenian: Desitin Pharma s.r.l Sevastopol street, no 13-17 Diplomat Business Centre, office 102 Sector 1, 010991 Bucharest Romania
English: After a baseline period of 1 month, placebo (n=20) or stiripentol (n=21) was added to valproate and clobazam during a double-blind period of 2 months.
Slovenian: Po izhodiščnem obdobju 1 meseca so kombinaciji valproata in klobazama v dvojno slepem obdobju 2 mesecev dodali placebo (n=20) ali stiriopentol (n=21).
English: In the mouse there was only a small increase in the incidence of hepatic adenomas and carcinomas in animals treated with 200 or 600 mg/kg/day for 78 weeks but not in those given 60 mg/kg/day.
Slovenian: Pri miših je prišlo do majhnega zvečanja pojavnosti jetrnih adenomov in karcinomov, če so živali prejemale 200 ali 600 mg/kg/dan 78 tednov.
English: • loss of appetite, weight loss (especially when combined with the antiepileptic medicine sodium valproate);
Slovenian: • izguba apetita, hujšanje (zlasti pri kombiniranju z natrijevim valproatom - zdravilom proti epilepsiji);
English: 5 How to store Diacomit Contents of the pack and other information
Slovenian: 5 Shranjevanje zdravila Diacomit Vsebina pakiranja in dodatne informacije
English: Liver function
Slovenian: Jetrna funkcija
English: This medicine contains less than 1 mmol sodium (23 mg) per capsule, that is to say essentially ‘sodium-free'.
Slovenian: To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na kapsulo, kar v bistvu pomeni »brez natrija«.
English: How to take the Diacomit powder for oral suspension The powder should be mixed in a glass of water and should be taken immediately after mixing during the meal.
Slovenian: Kako jemati prašek za peroralno suspenzijo Diacomit Prašek zmešajte v kozarcu vode in vsebino popijte takoj po pripravi, med obrokom.
English: Unless otherwise clinically indicated, blood counts should be checked every 6 months.
Slovenian: Če ni drugih kliničnih indikacij, je treba krvno sliko preveriti vsakih 6 mesecev.
English: The recommended dose of 50 mg/kg/day is based on the available clinical study findings and was the only dose of Diacomit evaluated in the pivotal studies (see section 5.1).
Slovenian: Priporočen odmerek 50 mg/kg/dan temelji na rezultatih in ugotovitvah klinične študije in je edini odmerek Diacomita, ki so ga ovrednotili v študijah, ki podpirajo vlogo za pridobitev dovoljenja za promet (glej poglavje 5.1).
English: This could occur by inhibition of synaptosomal uptake of GABA and/or inhibition of GABA transaminase.
Slovenian: To je lahko posledica zaviranja privzema GABA v sinapsah ali zaviranja GABA-transaminaze ali obojega.
English: With regard to topiramate, it is considered that potential competition of inhibition on CYP2C19 should not occur because it probably requires plasma concentrations 5-15 times higher than plasma concentrations obtained with the standard recommended topiramate dose and dosage schedules.
Slovenian: Predvideva se, da se pri topiramatu ne pojavlja potencialno tekmovanje za zaviranje CYP2C19, ker so za to verjetno potrebne 5-15-krat višje plazemske koncentracije od koncentracij, ki so v plazmi pri standardnem priporočenem odmerku topiramata ter načrtu odmerjanja.
English: BIOCODEX 1 avenue Blaise Pascal, 60000 Beauvais FRANCE
Slovenian: BIOCODEX 1 avenue Blaise Pascal, 60000 Beauvais FRANCIJA
English: The combination with Diacomit should be avoided as it may increase their blood levels, leading to digestive disorders, racing heart and insomnia.
Slovenian: Kombiniranju teh snovi z zdravilom Diacomit se je treba izogibati, saj lahko pride do zvišanja njunih koncentracij v krvi, kar povzroči prebavne težave, hitro bitje srca in nespečnost.
English: Plasma clearance decreases markedly at high doses; it falls from approximately 40 l/kg/day at the dose of 600 mg/day to about 8 l/kg/day at the dose of 2,400 mg. Clearance is decreased after repeated administration of stiripentol, probably due to inhibition of the cytochrome P450 isoenzymes responsible for its metabolism.
Slovenian: Pri velikih odmerkih se plazemski očistek zelo zmanjša; pade iz približno 40 l/kg/dan pri odmerku 600 mg/dan na približno 8 l/kg/dan pri odmerku 2.400 mg. Očistek se zmanjša po ponavljajočem dajanju stiripentola, verjetno zaradi zaviranja izoencimov citokroma P450, ki so odgovorni za presnovo stiripentola.
English: Growth rate of children
Slovenian: Hitrost rasti otroka
English: Stiripentol potentiates the efficacy of other anticonvulsants, such as carbamazepine, sodium valproate, phenytoin, phenobarbital and many benzodiazepines, as the result of pharmacokinetic interactions.
Slovenian: Stiripentol zveča učinkovitost ostalih antikonvulzivov (npr. karbamazepina, natrijevega valproata, fenitoina, fenobarbitala in številnih benzodiazepinov) kot posledica farmakokinetičnih interakcij.
English: As a result, no pharmacokinetic metabolic drug interaction between stiripentol and levetiracetam is anticipated.
Slovenian: Posledično ne pričakujemo farmakokinetične presnovne interakcije med stiripentolom in levetiracetamom.
English: In rodent models, stiripentol appears to increase brain levels of gamma-aminobutyric acid (GABA) - the major inhibitory neurotransmitter in mammalian brain.
Slovenian: Pri podganah stiripentol zviša ravni gama-aminomaslene kisline (GABA) v možganih, ki je poglavitni inhibitorni nevrotransmiter v možganih sesalcev.
English: Aspartame (E951) Sorbitol
Slovenian: Aspartam (E951)
English: No data on exposed pregnancies are available.
Slovenian: Ni na voljo podatkov od nosečnic, ki so bile izpostavljene zdravilu.
English: If you have the impression that the effect of this medicine is too strong or too weak, talk to your child's doctor or pharmacist.
Slovenian: Če menite, da je učinek zdravila Diacomit premočan ali prešibak, se posvetujte z otrokovim zdravnikom ali farmacevtom.
English: How to take the Diacomit capsules
Slovenian: Kako jemati zdravilo Diacomit kapsule
English: Increased risk of dose-dependent adverse reactions such as rhabdomyolysis (decreased hepatic metabolism of cholesterol-lowering medicinal product).
Slovenian: Povečano tveganje neželenih učinkov, ki so odvisni od odmerka, npr. rabdomioliza (zmanjšana jetrna presnova zdravil za znižanje ravni holesterola).
English: Likewise, the effect of stiripentol on their metabolism is not known.
Slovenian: Podobno tudi ni poznan vpliv stiripentola na njihovo presnovo.
English: Your child should always take these capsules exactly as your child's doctor has told you.
Slovenian: Vaš otrok mora jemati te kapsule natančno po navodilih otrokovega zdravnika.
English: For these children the use of stiripentol will be done under the close supervision of the doctor.
Slovenian: Uporaba stiripentola pri teh otrocih poteka pod skrbnim zdravnikovim nadzorom.
English: The pivotal clinical studies did not include children below 3 years old.
Slovenian: V ključne klinične študije zdravila Diacomit niso bili vključeni otroci, mlajši od 3 let.
English: In the event of an abnormal blood count or liver function test finding, the clinical decision for continuing use or adjusting the dose of stiripentol in conjunction with adjusting the doses of clobazam and valproate needs to be made on an individual patient basis taking into consideration the potential clinical benefits and risks (see section 4.4).
Slovenian: Če je rezultat krvne slike ali preiskave jetrne funkcije nenormalen, mora biti klinična odločitev o nadaljevanju uporabe oz. prilagoditvi odmerka stiripentola in odmerkov klobazama ter valproata sprejeta glede na posameznega bolnika ob upoštevanju potencialnih koristnih učinkov in tveganj (glejte poglavje 4.4).
English: Biocodex, 1 avenue Blaise Pascal - F-60000 Beauvais - France
Slovenian: Biocodex, 1 avenue Blaise Pascal - F-60000 Beauvais - Francija
English: • hyperkinesis (exaggerated movements);
Slovenian: • hiperkinezija (čezmerni gibi);
English: Stiripentol is an inhibitor of the enzymes CYP2C19, CYP3A4 and CYP2D6 and may markedly increase the plasma concentrations of substances metabolised by these enzymes and increase the risk of adverse reactions (see section 4.5).
Slovenian: Stiripentol je zaviralec encimov CYP2C19 in CYP3A4 in CYP2D6 ter lahko bistveno zviša plazemske koncentracije zdravil, ki se presnavljajo preko teh dveh encimov lahko poveča tveganje neželenih učinkov (glejte poglavje 4.5).
English: The most common side effects with stiripentol are anorexia, weight loss, insomnia, drowsiness, ataxia, hypotonia and dystonia.
Slovenian: Najpogostejši neželeni učinki stiripentola so anoreksija, zmanjšanje telesne mase, nespečnost, zaspanost, ataksija, hipotonija in distonija.
English: What you need to know before your child takes Diacomit
Slovenian: Kaj morate vedeti, preden bo vaš otrok vzel zdravilo Diacomit
English: • double vision when used in combination with the antiepileptic medicine carbamazepine;
Slovenian: • dvojni vid, če se zdravilo Diacomit uporabi v kombinaciji s karbamazepinom (zdravilom proti epilepsiji);
English: This medicine contains less than 1 mmol sodium (23 mg) per sachet, that is to say essentially ‘sodium-free'.
Slovenian: To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na vrečico, kar v bistvu pomeni »brez natrija«.
English: Systemic exposure to stiripentol increases markedly compared to dose proportionality.
Slovenian: Sistemska izpostavljenost stiripentolu se povečuje veliko hitreje kot sorazmerno z odmerkom.
English: Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, foetal development, parturition or postnatal development at non-maternotoxic doses (see section 5.3).
Slovenian: Študije na živalih za odmerke, ki niso toksični za brejo samico, ne kažejo neposrednih ali posrednih škodljivih vplivov na nosečnost, razvoj plodu, porod ali postnatalni razvoj (glejte poglavje 5.3).
English: 60 sachets
Slovenian: 60 vrečic
English: Data are limited about the use of stiripentol under 12 months of age.
Slovenian: Podatki o uporabi stiripentola pri otrocih, mlajših od 12 mesecev, so omejeni.
English: Undesirable combinations (to be avoided unless strictly necessary) - Rye ergot alkaloids (ergotamine, dihydroergotamine) Ergotism with possibility of necrosis of the extremities (inhibition of hepatic elimination of rye ergot).
Slovenian: Neželene kombinacije (kombinacije, ki se jim je treba izogniti, če ni absolutno nujno) - Alkaloidi rženega rožička (ergotamin, dihidroergotamin) Ergotizem z možno nekrozo okončin (zaviranje izločanja alkaloidov rženega rožička preko jeter).
English: 11121 Prague 1
Slovenian: s r.o Opletalova 25 11121 Prague 1
English: It should always be taken in combination with clobazam and valproate under the direction of a doctor.
Slovenian: To zdravilo mora otrok vedno jemati v kombinaciji s klobazomom in valproatiom po navodilih zdravnika.
English: Increased plasma benzodiazepine levels may occur via decreased hepatic metabolism leading to excessive sedation.
Slovenian: Zaradi zmanjšane presnove v jetrih lahko pride do zvišanih plazemskih koncentracij benzodiazepina, kar povzroči prekomerno sedacijo.
English: 90 sachets
Slovenian: 90 vrečic
English: It is used in conjunction with clobazam and valproate (other antiepileptic medicines) to treat a certain form of epilepsy called severe myoclonic epilepsy in infancy (Dravet's syndrome), which affects children.
Slovenian: Uporablja se sočasno s klobazamom in valproatom (drugi zdravili proti epilepsiji) za zdravljenje posebne oblike epilepsije, ki jo imenujemo huda mioklonična epilepsija v otroštvu (Dravetov sindrom).
English: Raised γ-GT
Slovenian: Preiskave zvišane ravni γ-GT
English: Stiripentol powder for oral suspension in sachet contains aspartame, a source of phenylalanine.
Slovenian: Stiripentol v obliki praška za peroralno suspenzijo v vrečici vsebuje aspartam, ki je vir fenilalanina.
English: In the absence of human studies on excretion in breast milk, and given that stiripentol passes freely from plasma into milk in the goat, breast-feeding is not recommended during treatment.
Slovenian: Študije o izločanju v materino mleko pri ljudeh niso bile opravljene, vendar stiripentol prosto prehaja iz plazme v mleko pri kozah, zato dojenje med zdravljenjem ni priporočljivo.
English: Potential medicinal product interactions affecting stiripentol
Slovenian: Možne interakcije, ki vplivajo na stiripentol
English: The hard capsules are supplied in plastic bottles containing 30, 60 or 90 capsules in cardboard cartons.
Slovenian: Trde kapsule so pakirane v plastenke s 30, 60 ali 90 kapsulami.
English: This medicine contains sorbitol: 2.4 mg in each 250mg-sachet and 4.8 mg in each 500mg-sachet.
Slovenian: To zdravilo vsebuje sorbitol: 2,4 mg v vsaki 250-mg vrečici in 4,8 mg v vsaki 500-mg vrečici.
English: Studies in the rat on fertility and general reproductive performance and on pre- and postnatal development were uneventful except for a minor reduction in the survival of pups nursed by mothers exhibiting toxic responses to stiripentol at a dose of 800 mg/kg/day (see section 4.6).
Slovenian: Pri podganah študije plodnosti, splošne sposobnosti razmnoževanja ter prenatalnega in postnatalnega razvoja niso pokazale učinkov, razen manjšega zmanjšanja preživetja mladičev, ki so jih dojile samice s toksičnim odzivom na stiripentol v odmerku 800 mg/kg/dan (glejte poglavje 4.6).
English: Stiripentol, the active ingredient of Diacomit, belongs to a group of medicines called antiepileptics.
Slovenian: Zdravilo Diacomit, ki vsebuje učinkovino stiripentol, spada v skupino antiepileptikov.
English: • rash, skin allergy, urticaria (pinkish, itchy swellings on the skin);
Slovenian: • izpuščaj, kožna alergija, urtikarija (rožnata, srbeča oteklina na koži);
English: Based on the clinical observations in this group of patients, there is no evidence to suggest that a change in topiramate dose and dosage schedules is needed if coadministered with stiripentol.
Slovenian: Pri kliničnem opazovanju v tej skupini bolnikov niso našli dokazov za spremembo odmerka topamirata oz. načrta odmerjanja pri sočasnem dajanju s stiripentolom.
English: As a consequence, it is recommended that children between 6 months and 3 years of age are carefully monitored whilst on Diacomit therapy.
Slovenian: Zato je priporočljivo natančno spremljanje otrok, starih od 6 mesecev do 3 let, ki se zdravijo z zdravilom Diacomit.
English: The initiation of adjunctive therapy with stiripentol should be undertaken gradually using upwards dose escalation to reach the recommended dose of 50 mg/kg/day administered in conjunction with clobazam and valproate.
Slovenian: Dopolnilno zdravljenje s stiripentolom uvajate postopno tako, da odmerke počasi večate do priporočene vrednosti, tj. 50 mg/kg/dan, skupaj z klobazamom in valproatom.
English: The second effect of stiripentol is mainly based on metabolic inhibition of several isoenzymes, in particular CYP450 3A4 and 2C19, involved in the hepatic metabolism of other anti-epileptic medicines.
Slovenian: Drugi učinek stiripentola temelji predvsem na presnovnem zaviranju več izoencimov, zlasti CYP450 3A4 in 2C19, ki sodelujeta pri presnovi drugih zdravil proti epilepsiji v jetrih.
English: Despite the absence of comprehensive pharmacology data on potential drug interactions, the following advice regarding modification of the dose and dosage schedules of other anti-epileptic medicinal products administered in conjunction with stiripentol is provided based on clinical experience.
Slovenian: Čeprav ni obsežnih farmakoloških podatkov o možnih interakcijah zdravila, so na osnovi kliničnih izkušenj predlagani naslednji ukrepi za spremembo odmerkov in načrtov odmerjanja drugih zdravil proti epilepsiji, ki se uporabljajo sočasno s stiripentolom.
English: Inhibition of CYP450 isoenzyme CYP2C19 and CYP3A4 may provoke pharmacokinetic interactions (inhibition of their hepatic metabolism) with phenobarbital, primidone, phenytoin, carbamazepine, clobazam (see section 4.2), valproate (see section 4.2), diazepam (enhanced myorelaxation), ethosuximide, and tiagabine.
Slovenian: Zaviranje CYP450 izoencimov CYP2C19 in CYP3A4 lahko povzroči farmakokinetične interakcije (zaviranje njihove presnove v jetrih) s fenobarbitalom, primidonom, fenitoinom, karbamazepinom, klobazamom (glejte poglavje 4.2), valproatom (glejte poglavje 4.2), diazepamom (povečana miorelaksacija), etosuksimidom in tiagabinom.
English: These capsules should be swallowed whole with water.
Slovenian: Kapsule je treba pogoltniti cele z vodo.
English: At therapeutic concentrations, stiripentol significantly inhibits several CYP450 isoenzymes: for example, CYP2C19, CYP2D6 and CYP3A4.
Slovenian: V terapevtskih koncentracijah stiripentol znatno zavira več izoencimov CYP450: na primer CYP2C19, CYP2D6 in CYP3A4.
English: Size 0, white capsule
Slovenian: trde kapsule bele kapsule velikosti 0