FrancophonIA/ELRC3.0 huggingface dataset:
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Danish: Tegn på knoglenekrose er stivhed, ømhed og smerter i led (specielt i hofte, knæ og skulder) samt bevægelsesbesvær.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each film-coated tablet contains nelfinavir mesilate corresponding to 250 mg of nelfinavir.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hver filmovertrukken tablet indeholder nelfinavirmesilat svarende til 250 mg nelfinavir.
English: Diabetes mellitus and hyperglycaemia: New onset diabetes mellitus, hyperglycaemia or exacerbation of existing diabetes mellitus has been reported in patients receiving PIs.
Danish: Diabetes mellitus og hyperglykæmi: For patienter i behandling med proteasehæmmere er der rapporteret nye tilfælde af diabetes mellitus, hyperglykæmi eller eksacerbation af eksisterende diabetes mellitus.
English: • Simvastatin or lovastatin (for lowering blood cholesterol)
Danish: • Simvastatin eller lovastatin (til nedsættelse af kolesterol i blodet)
English: Patients with chronic hepatitis B or C and treated with combination antiretroviral therapy are at an increased risk for severe and potentially fatal hepatic adverse events.
Danish: Patienter med kronisk hepatitis B eller C, og som bliver behandlet med antiretroviral kombinationsterapi, har en øget risiko for alvorlige og potentielt fatale leverkomplikationer.
English: Store in the original container.
Danish: Opbevares i original emballage.
English: A greater than dose-proportional increase in nelfinavir plasma concentrations was observed after single doses; however, this was not observed after multiple dosing.
Danish: Efter enkeltdoser observeredes en større stigning i nelfinavirplasmakoncentrationen end svarende til dosis-proportionaliteten; dette blev dog ikke set efter multipel dosering.
English: • Salmeterol (for asthma or chronic obstructive pulmonary disease (COPD))
Danish: • Salmeterol (mod astma eller kronisk obstruktiv lungesygdom (KOL))
English: • The other ingredients are microcrystalline cellulose, maltodextrin, dibasic potassium phosphate, crospovidone, hydroxypropyl methylcellulose, aspartame (E951), sucrose palmitate, and natural and artificial flavour.
Danish: • Øvrige indholdsstoffer: mikrokrystallinsk cellulose, maltodextrin, dikaliumphosphat, crospovidon, hypromellose, aspartam (E951), saccharosepalmitat samt naturligt og kunstigt smagsstof.
English: • Phenobarbital or carbamazepine (for fits or epilepsy)
Danish: • Phenobarbital eller carbamazepin (mod epilepsi)
English: Midazolam is extensively metabolised by CYP3A4.
Danish: Midazolam metaboliseres i stor udstrækning af CYP3A4.
English: The signs may include joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Danish: Symptomerne kan inkludere stivhed, ømhed og smerter i led (specielt i hofte, knæ og skulder) og bevægelsesbesvær.
English: Median baseline HIV-1 RNA was 4.98 log10 copies/ml and 5.01 log10 copies/ml in the nelfinavir and lopinavir/ritonavir treatment groups respectively.
Danish: Den mediane baseline hiv-1-RNA var hhv. 4,98 log10 kopier/ml og 5,01 log10 kopier/ml i nelfinavir- og lopinavir/ritonavirgrupperne.
English: HIV isolates from selected patients treated with nelfinavir alone or in combination with reverse transcriptase inhibitors were monitored for phenotypic (n=19) and genotypic (n=195, 157 of which were assessable) changes in clinical trials over a period of 2 to 82 weeks.
Danish: I de kliniske studier blev isolater fra udvalgte patienter, som var behandlet med nelfinavir alene eller i kombination med reverse transkriptasehæmmere, monitoreret i 2 til 82 uger for fænotypiske (n=19) og genotypiske forandringer (n=195, heraf kunne 157 vurderes).
English: • Atorvastatin or other statins (for lowering blood cholesterol)
Danish: • Atorvastatin eller andre statiner (til nedsættelse af kolesterol i blodet)
English: A reduction in colchicine dosage or an interruption of colchicine treatment is recommended in patients with normal renal or hepatic function if treatment with nelfinavir is required.
Danish: Hvis behandling med nelfinavir er påkrævet anbefales reduktion af colchicin-dosis eller afbrydelse af colchicin-behandlingen hos patienter med normal nyre- eller leverfunktion.
English: This may be harmful for people with phenylketonuria.
Danish: Det kan være skadeligt for patienter med fenylketonuri (PKU, Føllings sygdom).
English: Indinavir concentrations not measured
Danish: Indinavirkoncentrationer er ikke målt
English: • This medicine contains sucrose, which is a type of sugar.
Danish: • Dette lægemiddel indeholder saccharose.
English: The multi-dose pharmacokinetics of nelfinavir have not been studied in HIV-positive patients with hepatic insufficiency.
Danish: Nelfinavirs flerdosis-farmokokinetik er ikke blevet undersøgt hos hiv-positive patienter med leverinsufficiens.
English: It is recommended that HIV-infected women must not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Danish: For at undgå overførelse af hiv, anbefales det at hiv-smittede kvinder ikke under nogen omstændigheder ammer deres spædbørn.
English: Compared to control subjects with normal hepatic function, the AUC and Cmax of nelfinavir were not significantly different in subjects with mild impairment but were increased by 62% and 22%, respectively, in subjects with moderate hepatic impairment.
Danish: Sammenlignet med kontrolforsøgspersoner med normal leverfunktion var AUC og Cmax for nelfinavir ikke signifikant forskellige hos forsøgspersoner med mild leverinsufficiens, men var øget med henholdsvis 62 % og 22 % hos forsøgspersoner med moderat leverinsufficiens.
English: Conversely, following ritonavir therapy, 6 of 7 clinical isolates with decreased ritonavir susceptibility (8- to 113-fold) in vitro compared to baseline also exhibited decreased susceptibility to nelfinavir in vitro (5- to 40 fold).
Danish: Omvendt viste 6 af 7 kliniske isolater med nedsat følsomhed overfor ritonavir (med en faktor 8 til 113) in vitro, sammenlignet med baseline, også nedsat følsomhed overfor nelfinavir in vitro (med en faktor 5 til 40), efter behandling med ritonavir.
English: Coadministration of nelfinavir with simvastatin or lovastatin may result in significant increases in simvastatin and lovastatin plasma concentrations and is contraindicated (see section 4.3).
Danish: Samtidig administration af nelfinavir og simvastatin eller lovastatin kan resultere i signifikante stigninger i plasmakoncentrationerne af simvastatin og lovastatin og er kontraindiceret (se pkt.
English: The majority of patients in these studies received either 750 mg TID either alone or in combination with nucleoside analogues or 1250 mg BID in combination with nucleoside analogues.
Danish: De fleste patienter fik enten 750 mg tre gange daglig alene eller i kombination med nukleosidanaloger eller 1250 mg to gange daglig i kombination med nukleosidanaloger.
English: HMG-CoA reductase inhibitors (statins): HMG-CoA reductase inhibitors may interact with protease inhibitors and increase the risk of myopathy, including rhabdomyolysis.
Danish: HMG-CoA-reduktasehæmmere (statiner): Der kan forekomme interaktion mellem HMG-CoAreduktasehæmmere og proteasehæmmere og derved øget risiko for myopati, herunder rabdomyolyse.
English: Nelfinavir is primarily metabolised via the cytochrome P450 isoenzymes CYP3A4 and CYP2C19 (see section 5.2).
Danish: Nelfinavir bliver hovedsageligt metaboliseret via cytokrom P450 isoenzymerne CYP34A og CYP2C19 (se pkt.
English: There were increased liver weights and dose-related thyroid follicular cell hypertrophy in rats.
Danish: Hos rotter fandtes øget levervægt og dosis-relateret thyroid follikulær cellehypertrofi.
English: • Table 2: if you give the medicine two times a day (for children who weigh 18 kg or more), you will give 50-55 mg nelfinavir each time for each kg of body weight.
Danish: • Tabel 2: Hvis du giver lægemidlet to gange daglig (for børn, som vejer 18 kg eller mere), skal du give 50-55 mg nelfinavir hver gang for hvert kg kropsvægt.
English: The prescriber should advise the patient to use the handle of the second scoop to scrape off extra powder and obtain a level scoop.
Danish: Lægen bør råde patienten til at anvende håndtaget af den ene måleske til at fjerne overskydende oralt pulver for at få en strøget måleske.
English: • Herbal preparations containing St. John's Wort (for depression or improving your mood)
Danish: • Naturlægemidler, som indeholder perikon (mod depression eller til forbedring af dit humør)
English: Haemophiliac patients should therefore be made aware of the possibility of increased bleeding.
Danish: Bløderpatienter bør derfor gøres opmærksom på muligheden
English: Concurrent administration of salmeterol with VIRACEPT is not recommended.
Danish: Samtidig administration af salmeterol og VIRACEPT anbefales ikke.
English: Serious and non-serious adverse reactions from post-marketing spontaneous reports (where nelfinavir was taken as the sole protease inhibitor or in combination with other antiretroviral therapy), not mentioned previously in section 4.8, for which a causal relationship to nelfinavir cannot be excluded, are summarised below.
Danish: Nedenfor er opsummeret alvorlige og ikke alvorlige bivirkninger fra spontane rapporter efter markedsføring (hvor nelfinavir blev givet som eneste proteasehæmmer eller i kombination med anden antiretroviral behandling), der ikke tidligere er nævnt i pkt.
English: The mean decrease in plasma HIV RNA using a PCR assay (< 400 copies/ml) at 24 weeks was 2.33 log10 in patients receiving combination therapy with nelfinavir 750 mg TID, compared to 1.34 log10 in patients receiving zidovudine and lamivudine alone.
Danish: Gennemsnitsreduktion i plasma-hiv-RNA ved anvendelse af PCR assay (< 400 kopier/ml) ved 24 uger var 2,33 log10 i patienter, der fik kombinationsterapi med nelfinavir 750 mg tre gange daglig sammenlignet med 1,34 log10 hos patienter, der alene fik zidovudin og lamivudin.
English: Rare (≥ 0.01 % - ≤ 0.1 %): Blood creatine phosphokinase increased, myalgia, myositis and rhabdomyolysis have been reported with PIs, particularly in combination with nucleoside analogues.
Danish: Sjælden (≥ 0,01 % - ≤ 0,1 %): Forhøjet blod-kreatin-phosphokinase, myalgi, myositis og rhabdomyolyse er rapporteret med PI, specielt i kombination med nukleosidanaloger.
English: Dose adjustment is not needed when nevirapine is administered with nelfinavir.
Danish: Dosisjustering er ikke nødvendig når nevirapin administreres sammen med nelfinavir.
English: Plasma levels of nelfinavir, which is metabolised predominantly by CYP2C19 and only partially by CYP3A4, are not greatly increased by co-administration with ritonavir, and therefore nelfinavir does not require co-administration with low-dose ritonavir .
Danish: Plasmakoncentrationerne af nelfinavir, som fortrinsvis metaboliseres af CYP2C19 og kun delvis af CYP3A4, øges kun lidt ved samtidig administration af ritonavir og derfor er det ikke nødvendigt at administrere nelfinavir samtidig med lavdosis ritonavir.
English: A second study evaluated the steady state pharmacokinetics of nelfinavir (1250 mg twice daily for 2 weeks) in adult HIV-seronegative subjects with mild (Child-Pugh A; n=6) or moderate (Child-Pugh B; n=6) hepatic impairment.
Danish: Et andet studie vurderede nelfinavirs steady-state farmakokinetik (1250 mg to gange daglig i 2 uger) hos voksne hiv-seronegative forsøgspersoner med mild (Child-Pugh A; n=6) eller moderat (Child-Pugh B; n=6) leverinsufficiens.
English: In a study of 297 HIV-1 seropositive patients receiving zidovudine and lamivudine plus nelfinavir (2 different doses) or zidovudine and lamivudine alone, the mean baseline CD4 cell count was 288 cells/mm3 and the mean baseline plasma HIV RNA was 5.21 log10 copies/ml (160,394 copies/ml).
Danish: I et studie af 297 hiv-1-seropositive patienter som fik zidovudin og lamivudin sammen med nelfinavir (i to forskellige doser) eller zidovudin eller lamivudin alene, var gennemsnitsbaseline CD4-celletallet 288 celler/mm³ og gennemsnitsbaseline hiv-RNA i plasme var 5,21 log10 kopier/ml (160.394 kopier/ml).
English: Patients with chronic hepatitis B or C and treated with anti-retroviral agents are at increased risk for severe and potentially fatal liver adverse events and may require blood tests for control of liver function.
Danish: Patienter med kronisk hepatitis B eller C, og som bliver behandlet med antiretrovirale lægemidler, har øget risiko for alvorlige og potentielt dødelige leverskader, hvilket kan kræve blodprøver til kontrol af leverfunktionen.
English: PDE-5 inhibitors for the treatment of erectile dysfunction (ED) Tadalafil
Danish: PDE-5-hæmmere til behandling af erektil dysfunktion (ED)
English: Each bottle contains 144 grams of oral powder and is supplied with a 1 gram (white) and a 5 gram (blue) polypropylene scoop.
Danish: Hver flaske indeholder 144 gram oralt pulver, som leveres sammen med en 1 gram (hvid) polystyren måleske og en 5 gram (blå) polystyren måleske.
English: Pregnancy, contraception and breast-feeding • Talk to your doctor before you take Viracept if you are pregnant or planning to become
Danish: • Tal med din læge før du tager Viracept, hvis du er gravid eller planlægger at blive gravid.
English: Excipients: - Contains sucrose palmitate: 10.0 mg per gram of oral powder.
Danish: - indeholder saccharosepalmitat: 10,0 mg pr. gram oralt pulver.
English: Uncommon - rare (≥ 0.01 % - ≤ 1 %): Combination antiretroviral therapy has been associated with redistribution of body fat (Lipodystrophy aquired) in HIV patients including the loss of peripheral and facial subcutaneous fat, increased intra-abdominal and visceral fat, breast hypertrophy and dorsocervical fat accumulation (lipohypertrophy buffalo hump).
Danish: Ikke almindelig - sjælden (≥ 0,01 % - ≤ 1 %): Antiretroviral kombinationsbehandling er, hos patienter med hiv, associeret med omfordeling af kropsfedt (erhvervet lipodystrofi), inklusive tab af perifert subkutant fedt og subkutant fedt i ansigtet, øget intraabdominalt og visceralt fedt, brysthypertrofi og dorsocervikal fedtakkumulering (lipohypertrofi, bøffel-pukkel).
English: As these data come from the spontaneous reporting system, the frequency of the adverse reactions is unknown: hypertriglyceridemia, anaemia, blood lactic acid increased, and pneumonia.
Danish: Frekvenserne for bivirkningerne er ukendte, da disse data kommer fra det spontane rapporteringssystem: Hypertriglyceridæmi, anæmi, forhøjet mælkesyre i blodet og pneumoni.
English: Median baseline CD4+ cell counts were 177 and 166 x106 cells/l for the nelfinavir and fosamprenavir/ritonavir groups respectively.
Danish: Det mediane baseline CD4+ celletal var henholdsvis 177 og 166 x106 celler/l i nelfinavir- og fosamprenavir/ritonavirgrupperne.
English: • Sildenafil (for pulmonary arterial hypertension (PAH))
Danish: • Sildenafil (mod pulmonal arteriel hypertension)
English: Median baseline CD4+ cell count was 232 cells/mm3
Danish: Det mediane baseline CD4+ celletal var 232 celler/mm3 i begge grupper.
English: Concomitant use of sildenafil prescribed for the treatment of pulmonary arterial hypertension with VIRACEPT is contraindicated (see section 4.3).
Danish: Samtidig brug af VIRACEPT og sildenafil ordineret til behandling af pulmonal arteriel hypertension er kontraindiceret (se pkt.
English: Consider alternatives to fluticasone propionate, that are not metabolised by CYP3A4, such as beclometasone, particularly for long-term use.
Danish: Overvej alternativer til fluticasonpropionat, som ikke metaboliseres af CYP3A4, såsom beclomethason, specielt ved langvarigt brug.
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, 4.2.)
Danish: Lægemidlet må kun udleveres efter begrænset recept (jf. bilag I: Produktresumé; pkt.
English: Gastrointestinal disorders Very common
Danish: Mave-tarmkanalen Meget almindelig
English: Liver Disease: The safety and efficacy of nelfinavir has not been established in patients with significant underlying liver disorders.
Danish: Leversygdom: Sikkerheden og effekten af nelfinavir er ikke efterprøvet hos patienter med betydelige tilgrundliggende leversygdomme.
English: Coadministration of warfarin and VIRACEPT may affect concentrations of warfarin.
Danish: Samtidig administration af warfarin og VIRACEPT kan påvirke plasmakoncentrationen af warfarin.
English: • Tadalafil (for pulmonary arterial hypertension (PAH), or for getting or keeping an erection)
Danish: • Tadalafil (mod pulmonal arteriel hypertension eller for at opnå eller bibeholde erektion)
English: Trough drug exposures remain at least twenty fold greater than the mean IC95 throughout the dosing interval for both regimens.
Danish: For begge grupper er trough-koncentrationerne i hele dosisintervallet mindst tyve gange højere end middel-IC95.
English: In rats administration of 1000 mg/kg/day resulted in increased incidences of thyroid follicular cell adenoma and carcinoma, relative to those for controls.
Danish: Hos rotter gav oral administration af 1000 mg/kg/dag igennem to år en forhøjet hyppighed af follikulære celleadenomer og carcinomer i thyreoidea i forhold til kontrolgruppen.
English: • Warfarin (for lowering the chance of blood clots in your body)
Danish: • Warfarin (for at nedsætte risikoen for blodpropper)
English: Other HMG-CoA reductase inhibitors may also interact with protease inhibitors and should be used with caution .
Danish: Andre HMG-CoA-reduktasehæmmere kan muligvis også interferere med proteasehæmmere og bør derfor anvendes med forsigtighed.
English: Uncommon (≥ 0.1 % - ≤ 1 %): vomiting, pancreatitis/blood amylase increased.
Danish: Ikke almindelig (≥ 0,1 % - ≤ 1 %): Opkastning, pancreatitis/forhøjet blodamylase.
English: Driving and using machines Viracept is not likely to affect you being able to drive or use any tools or machines.
Danish: Det er ikke sandsynligt, at Viracept vil påvirke din evne til at køre bil eller betjene værktøj eller
English: Each tablet contains 250 mg of nelfinavir.
Danish: Hver tablets indeholder 250 mg nelfinavir.
English: Do not store above 30°C.
Danish: Må ikke opbevares ved temperatur over 30 °C.
English: Rare (≥ 0.01 % - ≤ 0.1 %): new onset diabetes mellitus, or exacerbation of existing diabetes mellitus.
Danish: Sjælden (≥ 0,01 % - ≤ 0,1 %): Nyopstået diabetes mellitus eller eksacerbation af eksisterende diabetes mellitus.
English: Non-nucleoside Analogue Reverse Transcriptase Inhibitors (NNRTIs) Efavirenz 600 mg QD (Nelfinavir 750 mg TID)
Danish: Non-nukleosid reverse transkriptasehæmmere (NNRTIs) Efavirenz 600 mg 1 gang daglig (Nelfinavir 750 mg 3 gange daglig)
English: Administration of VIRACEPT oral powder or tablets at a dose of approximately 25-30 mg/kg TID with food achieves steady-state plasma concentrations that are similar to those achieved in adult patients receiving 750 mg TID.
Danish: Ved administration af føde sammen med VIRACEPT oralt pulver eller tabletter ved en dosis på ca. 25-30 mg/kg tre gange dagligt opnås steady-state plasmakoncentrationer, svarende til dem der opnås hos voksne patienter, som fik 750 mg tre gange dagligt.
English: Clinical isolates (n=5) with decreased susceptibility to zidovudine, lamivudine, or nevirapine remain fully susceptible to nelfinavir in vitro.
Danish: Kliniske isolater (n=5) med nedsat følsomhed overfor zidovudin, lamivudin eller nevirapin forbliver
English: At week 48, non-inferiority was shown with 68 % of patients in the group treated with nelfinavir and 69 % patients treated with fosamprenavir/ritonavir having plasma HIV-1 RNA <400 copies/ml whereas 53 % in the nelfinavir and 55 % in the fosamprenavir/ritonavir patients had HIV-1 RNA <50 copies/ml (intent-to-treat, rebound/discontinuation = failure).
Danish: Efter 48 uger vistes non-inferiority, idet 68 % af patienterne i nelfinavirgruppen og 69 % af patienterne behandlet med fosamprenavir/ritonavir havde < 400 kopier/ml plasma hiv-1-RNA, mens 53 % af nelfinavir- og 55 % af fosamprenavir/ritonavirpatienterne havde < 50 kopier/ml hiv-1-RNA (intent-to-treat, rebound/seponering = svigt).
English: The effects of nelfinavir (alone or combined with other antiretroviral agents) on biological markers of disease activity, CD4 cell count and viral RNA, were evaluated in several studies involving HIV-1 infected patients.
Danish: Nelfinavirs virkning (alene eller kombineret med andre antiretrovirale midler) på biologiske markører, CD4-celletal og virus-RNA blev evalueret i adskillige
English: Patients receiving VIRACEPT TID (n=11) achieved nelfinavir peak plasma concentrations (Cmax) of 3.0 ± 1.6 µg/ml and morning and evening trough concentrations of 1.4 ± 0.6 µg/ml and 1.0 ± 0.5 µg/ml, respectively.
Danish: De patienter, der fik VIRACEPT tre gange daglig (n=11) opnåede Cmax nelfinavir på 3,0 ± 1,6 μg/ml og trough-koncentrationer om morgenen og aftenen på hhv. 1,4 ± 0,6 μg/ml og 1,0 ± 0,5 μg/ml.
English: • Vardenafil (for pulmonary arterial hypertension (PAH), or for getting or keeping an erection)
Danish: • Vardenafil (mod pulmonal arteriel hypertension eller for at opnå eller bibeholde erektion)
English: None of the subjects experienced withdrawal symptoms in this study; however, due to the pharmacokinetic changes, it should be expected that some patients who received this combination may experience withdrawal symptoms and require an upward adjustment of the methadone dose.
Danish: På grund af farmakokinetiske ændringer kan det dog forventes, at nogle patienter, som får denne kombination, vil udvikle abstinenssymptomer og vil behøve en højere methadondosis.
English: Immune Reactivation Syndrome: In HIV-infected patients with severe immune deficiency at the time of institution of combination antiretroviral therapy (CART), an inflammatory reaction to asymptomatic or residual opportunistic pathogens may arise and cause serious clinical conditions, or aggravation of symptoms.
Danish: Immun reaktiveringssyndrom: Hos hiv-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske patogener, som kan forårsage alvorlige kliniske tilstande eller forværring af symptomer.
English: over 22 kg * Children with these weights will be given an uneven number of tablets during the day.
Danish: * Børn, hvis legemsvægt ligger indenfor disse intervaller, vil få et forskelligt antal tabletter i løbet af dagen.
English: Safety of combination not established; combination not recommended
Danish: Sikkerheden ved kombinationen er ikke fastlagt.
English: The recommended dose of VIRACEPT oral powder to be administered TID to children aged 3 to 13 years, using a combination of both the white 1 gram and the blue 5 gram scoop is shown in the following table.
Danish: Den anbefalede dosis af VIRACEPT oralt pulver til indgivelse tre gange daglig til børn mellem 3 og 13 år ved anvendelse af en kombination af både den hvide 1 grams måleske og den blå 5 grams måleske fremgår af følgende tabel.
English: Through 48 weeks of therapy, a statistically significantly higher proportion of patients in the lopinavir/ritonavir arm had HIV-1 RNA < 50 copies/ml compared to the nelfinavir arm.
Danish: Efter 48 ugers behandling havde en statistisk signifikant større del af patienterne i lopinavir/ritonavir-armen < 50 kopier/ml hiv-1-RNA sammenlignet med nelfinavirarmen.
English: % Fat Number of Subjects
Danish: Antal kcal. % fedt Antal forsøgspersoner
English: Caution is recommended when nelfinavir is co-administered with other proton pump inhibitors
Danish: Forsigtighed anbefales når nelfinavir administreres sammen med andre syrepumpehæmmere
English: Co-administration of tadalafil for the treatment of pulmonary arterial hypertension with Viracept is not recommended.
Danish: VIRACEPT og tadalafil til behandling af pulmonal arteriel hypertension anbefales ikke.
English: Potent inducers of CYP3A (e.g., rifampicin, phenobarbital and carbamazepine) reduce nelfinavir plasma concentrations.
Danish: Potente induktorer af CYP3A (f.eks. rifampicin, phenobarbital og carbamazepin) kan reducere nelfinavirs plasmakoncentrationer.