FrancophonIA/ELRC3.0 huggingface dataset:
English: Split the dose based on individual patient's needs and administer with main meals.
Slovenian: Odmerek je treba razdeliti glede na potrebe posameznega bolnika, bolnik pa ga naj uporablja z glavnima obrokoma.
English: Ryzodeg can be used in renal and hepatic impaired patients.
Slovenian: Zdravilo Ryzodeg se lahko uporablja pri bolnikih z ledvično in jetrno okvaro.
English: In all trials in type 2 diabetes mellitus, oral antidiabetic drugs (OADs) were allowed.
Slovenian: V vseh preskušanjih pri sladkorni bolezni tipa 2 je bila dovoljena uporaba peroralnih antidiabetikov (POAD).
English: Degradation of insulin degludec and insulin aspart is similar to that of human insulin; all metabolites formed are inactive.
Slovenian: Razgradnja insulina degludek in insulina aspart je podobna razgradnji človeškega insulina; vsi nastali presnovki so neaktivni.
English: The recommended starting dose of Ryzodeg is 60-70% of the total daily insulin requirements in combination with short-/rapid-acting insulin at the remaining meals followed by individual dosage adjustments.
Slovenian: Priporočeni začetni odmerek zdravila Ryzodeg obsega 60-70 % celotne dnevne potrebe po insulinu v kombinaciji s kratko-/hitrodelujočim insulinom, ki se uporablja ob preostalih obrokih, čemur sledi individualna prilagoditev odmerka.
English: Ryzodeg causes a lower rate of overall and nocturnal hypoglycaemia (Table 2).
Slovenian: Zdravilo Ryzodeg povzroča manj vseh hipoglikemij in nočnih hipoglikemij (preglednica 2).
English: You can carry your Ryzodeg cartridge (Penfill) with you and keep it at room temperature (not above 30°C) for up to 4 weeks.
Slovenian: Vložek Ryzodeg Penfill lahko nosite s seboj in shranjujete na sobni temperaturi (do 30 °C) do 4 tedne.
English: Substances added to Ryzodeg may cause degradation of insulin degludec and/or insulin aspart.
Slovenian: Dodajanje snovi zdravilu Ryzodeg bi lahko povzročilo razgradnjo insulina degludek in/ali insulina aspart.
English: If you have kidney or liver problems, you may need to check your blood sugar level more often.
Slovenian: Če imate težave z ledvicami ali jetri Če imate težave z ledvicami ali jetri, si morate krvni sladkor kontrolirati pogosteje.
English: It is not known if Ryzodeg affects the baby in pregnancy or during breast-feeding.
Slovenian: Ni znano, ali zdravilo Ryzodeg vpliva na otroka med nosečnostjo ali dojenjem.
English: Before you use Ryzodeg for the first time, your doctor or nurse will show you how to use it.
Slovenian: Pred prvo uporabo zdravila Ryzodeg vam bosta zdravnik ali medicinska sestra pokazala, kako se ga uporablja.
English: Ryzodeg can be used in the elderly.
Slovenian: Zdravilo Ryzodeg se lahko uporablja pri starostnikih.
English: Important information about some of the ingredients in Ryzodeg
Slovenian: Pomembne informacije o nekaterih sestavinah zdravila Ryzodeg
English: Patients must be instructed to always check the insulin label before each injection to avoid accidental mix-ups between Ryzodeg and other insulin products.
Slovenian: Bolnike je treba opozoriti, da pred injiciranjem vedno preverijo nalepko insulina, da po pomoti ne zamenjajo zdravila Ryzodeg in drugih insulinskih zdravil.
English: This assessment supports the use of Ryzodeg in adolescent patients with type 2 diabetes mellitus.
Slovenian: Ocena podpira uporabo zdravila Ryzodeg pri mladostnikih s sladkorno boleznijo tipa 2.
English: • Unscrew the needle and dispose of it carefully.
Slovenian: • Odvijte iglo in jo pazljivo zavrzite.
English: After subcutaneous injection, soluble and stable multi-hexamers of insulin degludec are formed creating a depot of insulin in the subcutaneous tissue, while not interfering with the rapid release of insulin aspart monomers into the circulation.
Slovenian: Absorpcija Po subkutani injekciji se tvorijo topni in stabilni multiheksameri insulina degludek in s tem ustvarijo depo insulina v podkožnem tkivu, hkrati pa ne ovirajo hitrega sproščanja monomerov insulina aspart v obtok.
English: Do not use Ryzodeg
Slovenian: Ne uporabljajte zdravila Ryzodeg:
English: They may make it harder to recognise the warning signs of too low blood sugar (see section 4 ‘Warning signs of too low blood sugar')
Slovenian: Zaradi teh zdravil bo morda težje prepoznati opozorilne znake prenizkega krvnega sladkorja (glejte poglavje 4, podpoglavje »Opozorilni znaki prenizkega krvnega sladkorja«);
English: It is unknown whether insulin degludec/insulin aspart is excreted in human milk.
Slovenian: Ni znano, ali se insulin degludek in insulin aspart izločata v materino mleko.
English: The rapid absorption characteristics of the well-established insulin aspart are maintained by Ryzodeg.
Slovenian: Hitra absorpcija dobro poznanega insulina aspart je v zdravilu Ryzodeg ohranjena.
English: Steady-state serum concentration of the basal component (insulin degludec) is reached after 2-3 days of daily Ryzodeg administration.
Slovenian: Serumska koncentracija v stanju dinamičnega ravnovesja bazalne sestavine (insulina degludek) je dosežena po 2 do 3 dneh vsakodnevne uporabe zdravila
English: Steady state will occur after 2-3 days of dose administration.
Slovenian: Stanje dinamičnega ravnovesja je doseženo po 2 do 3 dneh uporabe.
English: EU/1/12/806/001 1 pen of 3 mL EU/1/12/806/002 1 pen of 3 mL and 7 NovoFine needles EU/1/12/806/003 1 pen of 3 mL and 7 NovoTwist needles EU/1/12/806/004 5 pens of 3 mL
Slovenian: EU/1/12/806/001 1 injekcijski peresnik po 3 ml EU/1/12/806/002 1 injekcijski peresnik po 3 ml in 7 igel NovoFine EU/1/12/806/003 1 injekcijski peresnik po 3 ml in 7 igel NovoTwist EU/1/12/806/004 5 injekcijskih peresnikov po 3 ml
English: • if the cartridge is damaged or has not been stored correctly (see section 5 ‘How to store
Slovenian: • če je injekcijski peresnik poškodovan ali ni bil pravilno shranjen (glejte poglavje 5
English: eat more or exercise less than usual; drink alcohol; get an infection or a fever; have not used enough insulin; keep using less insulin than you need; forget to use your insulin or stop using insulin without talking to your doctor.
Slovenian: Previsok krvni sladkor se vam lahko pojavi, če: jeste več kot ponavadi ali ste manj telesno dejavni kot ponavadi, pijete alkohol, imate okužbo ali zvišano telesno temperaturo, uporabite premalo insulina, večkrat zapored uporabite manj insulina, kot ga potrebujete, pozabite ali prenehate uporabljati insulin, ne da bi se prej posvetovali z zdravnikom.
English: Ryzodeg (o.d.)1
Slovenian: Ryzodeg (1x/dan)1
English: If you forget a dose, inject the missed dose with your next large meal on that day and thereafter resume your usual dosing schedule.
Slovenian: Če pozabite odmerek, si injicirajte pozabljeni odmerek ob naslednjem obilnem obroku dneva in potem nadaljujte s predpisanim odmerjanjem.
English: • Basal insulin called insulin degludec, this has a long blood sugar-lowering effect.
Slovenian: • bazalni insulin, ki se imenuje insulin degludek - dolgotrajno znižuje krvni sladkor,
English: When changing from another insulin regimen to Ryzodeg, dose reduction of total insulin needs to be considered on an individual basis in order to minimise the risk of hypoglycaemia (see section 4.4).
Slovenian: Pri zamenjavi insulina z zdravilom Ryzodeg je pri vsakem bolniku posebej treba presoditi o zmanjšanju celokupnega odmerka insulina, da se zmanjša tveganje za pojav hipoglikemije (glejte poglavje 4.4).
English: An efficacy and safety evaluation for adolescent patients with type 2 diabetes mellitus has been made using data from adolescent and adult patients with type 1 diabetes mellitus and adult patients with type 2 diabetes mellitus.
Slovenian: Korist in varnost zdravila pri mladostnikih s sladkorno boleznijo tipa 2 so ocenili s pomočjo podatkov, pridobljenih pri mladostnikih in odraslih s sladkorno boleznijo tipa 1 ter odraslih bolnikih s sladkorno boleznijo tipa 2.
English: Treatment of diabetes mellitus in adults, adolescents and children from the age of 2 years.
Slovenian: Zdravljenje sladkorne bolezni pri odraslih, mladostnikih in otrocih, starih 2 leti in več.
English: The trial had a median duration of 2 years and compared the cardiovascular safety of insulin degludec vs insulin glargine (100 units/mL) in 7,637 patients with type 2 diabetes mellitus at high risk of cardiovascular events.
Slovenian: V preskušanju z medianim trajanjem 2 leti so primerjali insulin degludek in insulin glargin (100 enot/ml) glede varnosti za pojav srčno-žilnih dogodkov pri 7637 bolnikih s sladkorno boleznijo tipa 2 in z velikim tveganjem za srčno-žilne dogodke.
English: Ryzodeg 100 units/mL solution for injection in pre-filled pen EU/1/12/806/001
Slovenian: Ryzodeg 100 enot/ml raztopina za injiciranje v napolnjenem injekcijskem peresniku EU/1/12/806/001
English: The pre-filled pen can provide a dose of 1-80 units in one injection in steps of 1 unit.
Slovenian: Napolnjen injekcijski peresnik lahko injicira 1-80 enot v eni injekciji, v korakih po 1 enoto.
English: What Ryzodeg looks like and contents of the pack
Slovenian: Izgled zdravila Ryzodeg in vsebina pakiranja
English: • Too low blood sugar (hypoglycaemia)
Slovenian: • Prenizek krvni sladkor (hipoglikemija)
English: Total exposure of insulin degludec after single dose administration was, however, higher in children and adolescents than in adults with type 1 diabetes mellitus.
Slovenian: Celotna izpostavljenost insulinu degludek po enkratnem odmerku pa je pri otrocih in mladostnikih večja kot pri odraslih s sladkorno boleznijo tipa 1.
English: Ryzodeg can be used in adolescents and children from the age of 2 years with diabetes mellitus.
Slovenian: Zdravilo Ryzodeg se lahko uporablja pri mladostnikih in otrocih, starejših od 2 let, s sladkorno boleznijo.
English: • The active substances are insulin degludec and insulin aspart.
Slovenian: • Učinkovini sta insulin degludek in insulin aspart.
English: The recommended total daily starting dose is 10 units with meal(s) followed by individual dosage adjustments.
Slovenian: Priporočeni začetni skupni dnevni odmerek je 10 enot ob obrokih, čemur sledi prilagoditev odmerjanja posamezniku.
English: Before you use Ryzodeg for the first time, your doctor or nurse will show you how to use the pre-filled pen.
Slovenian: Pred prvo uporabo zdravila Ryzodeg vam bosta zdravnik ali medicinska sestra pokazala, kako se uporablja napolnjen injekcijski peresnik.
English: The pharmacokinetic properties of Ryzodeg in type 1 diabetes mellitus were investigated in children (6-11 years) and adolescents (12-18 years) and compared to adults after single dose administration.
Slovenian: Farmakokinetične lastnosti zdravila Ryzodeg pri zdravljenju sladkorne bolezni tipa 1 so raziskali pri otrocih (od 6. do 11. leta) in mladostnikih (od 12. do 18. leta) in jih primerjali s tistimi pri odraslih po aplikaciji enega odmerka.
English: Ryzodeg 100 units/mL solution for injection in pre-filled pen After first opening or carried as a spare, the medicinal product may be stored for a maximum of 4 weeks.
Slovenian: Ryzodeg 100 enot/ml raztopina za injiciranje v napolnjenem injekcijskem peresniku Po prvem odprtju ali ko se uporablja kot rezerva, se lahko zdravilo shranjuje največ 4 tedne.
English: The rates (events per patient-year of exposure) of confirmed hypoglycaemia (ISPAD 2009 definition: 46.23 vs 49.55) and nocturnal confirmed hypoglycaemia (5.77 vs 5.40) were comparable with Ryzodeg vs insulin detemir whereas the rate of severe hypoglycaemia (0.26 vs 0.07) was higher in the Ryzodeg arm although the difference was not statistically significant.
Slovenian: 46,23 v primerjavi z 49,55) in potrjene nočne hipoglikemije (5,77 v primerjavi s 5,40) so bili pri zdravilu Ryzodeg primerljivi z deleži pri insulinu detemir, delež hude hipoglikemije pa je bil v skupini z zdravilom Ryzodeg večji (0,26 v primerjavi z 0,07), čeprav razlika ni bila statistično značilna.
English: Detailed instructions accompanying the pre-filled pen must be followed.
Slovenian: Upoštevati je treba podrobno navodilo, priloženo napolnjenemu injekcijskemu peresniku.
English: • The other ingredients are glycerol, metacresol, phenol, sodium chloride, zinc acetate, hydrochloric acid and sodium hydroxide (for pH adjustment) and water for injections (see section 2).
Slovenian: • Druge sestavine zdravila so glicerol, metakrezol, fenol, natrijev klorid, cinkov acetat, klorovodikova kislina in natrijev hidroksid (za uravnavanje pH) in voda za injekcije (glejte poglavje 2).
English: The steady-state pharmacokinetic properties of the insulin degludec component of Ryzodeg were investigated using a population pharmacokinetic analysis in children down to 1 year of age.
Slovenian: Farmakokinetične lastnosti insulina degludek, sestavine zdravila Ryzodeg, v stanju dinamičnega ravnovesja so na osnovi analize populacijske farmakokinetike raziskali pri otrocih, starejših od 1 leta.
English: The efficacy and safety of Ryzodeg have been studied in a randomised controlled clinical trial in children and adolescents with diabetes mellitus type 1 for a period of 16 weeks (n=362).
Slovenian: Učinkovitost in varnost uporabe zdravila Ryzodeg so raziskovali v randomiziranem nadzorovanem kliničnem preskušanju pri otrocih in mladostnikih s sladkorno boleznijo tipa 1 v obdobju 16 tednov
English: This medicinal product is to be used once daily at mealtime in combination with short-/rapid-acting insulin at the remaining meals followed by individual dosage adjustments.
Slovenian: To zdravilo je treba uporabljati enkrat dnevno ob obroku, v kombinaciji s kratko-/hitrodelujočim insulinom ob preostalih obrokih; slediti mora individualna prilagoditev odmerka.
English: The pharmacokinetic properties of insulin degludec in children (1-11 years) and adolescents (1218 years) were at steady state comparable to those observed in adults with type 1 diabetes mellitus.
Slovenian: Farmakokinetične lastnosti insulina degludek pri otrocih (od 1. do 11. leta) in mladostnikih (od 12. do 18. leta) so v stanju dinamičnega ravnovesja primerljive s tistimi pri odraslih s sladkorno boleznijo tipa 1.
English: You can carry your Ryzodeg pre-filled pen (FlexTouch) with you and keep it at room temperature (not above 30°C) or in a refrigerator (2°C to 8°C) for up to 4 weeks.
Slovenian: Napolnjen injekcijski peresnik Ryzodeg FlexTouch lahko nosite s seboj in shranjujete na sobni temperaturi (do 30 °C) ali v hladilniku (2 °C - 8 °C) do 4 tedne.
English: Having too low or too high blood sugar can affect your ability to drive or use any tools or machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Če imate prenizek ali previsok krvni sladkor, lahko to vpliva na vašo sposobnost za upravljanje vozil ter uporabo orodij in strojev.
English: Do not use this medicine after the expiry date which is stated on the Penfill label and carton, after ‘EXP'.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki vložka Penfill in škatli, poleg oznake »Uporabno do«.
English: The ratio of mitogenic relative to metabolic potency for insulin degludec is comparable to that of human insulin.
Slovenian: Razmerje mitogene moči v primerjavi s presnovno močjo je pri insulinu degludek podobno kot pri človeškem insulinu.
English: If a dose of this medicinal product is missed, the patient can take the missed dose with the next main meal of that day and thereafter resume the usual dosing schedule.
Slovenian: Če bolnik izpusti odmerek tega zdravila, si lahko izpuščeni odmerek aplicira ob naslednjem glavnem obroku istega dneva in nato nadaljuje predpisano odmerjanje.
English: 1 Twice-daily regimen ± metformin ± pioglitazone ± DPP-4 inhibitor 2 Twice-daily regimen ± metformin
Slovenian: 1 Shema dvakrat na dan ± metformin ± pioglitazon ± zaviralec DPP-4
English: • Ensuring you use the right type of insulin - always check the insulin label before each injection to avoid accidentally confusing Ryzodeg with other insulin products.
Slovenian: • uporabo pravega insulina; pred injiciranjem vedno preverite nalepko insulina, da po pomoti ne zamenjate zdravila Ryzodeg in drugih insulinskih zdravil.
English: Prandial Blood glucose Increment 90 minutes after dosing meal (Plasma) (mmol/L)
Slovenian: Prandialni porast glukoze v krvi 90 minut po obroku z aplikacijo zdravila (plazma) (mmol/l) Na koncu preskušanja
English: At week 16, the mean total daily insulin dose was 0.88 vs 1.01 units/kg in the Ryzodeg and insulin detemir arms, respectively.
Slovenian: V 16. tednu je bil celoten povprečni dnevni odmerek insulina v skupini z zdravilom Ryzodeg 0,88 enot/kg, v skupini z insulinom detemir pa 1,01 enot/kg.
English: This medicinal product is a soluble insulin product consisting of the basal insulin degludec and the rapid-acting prandial insulin aspart.
Slovenian: To zdravilo je topno insulinsko zdravilo, sestavljeno iz bazalnega insulina degludek in hitrodelujočega prandialnega insulina aspart.
English: Patients with type 2 diabetes mellitus Ryzodeg can be administered once or twice daily with the main meal(s) alone, in combination with oral antidiabetic medicinal products, and in combination with bolus insulin (see section 5.1).
Slovenian: Zdravilo Ryzodeg se lahko uporablja enkrat ali dvakrat na dan z glavnim obrokom (glavnima obrokoma), in sicer sámo, v kombinaciji s peroralnimi antidiabetiki in v kombinaciji z bolusnim insulinom (glejte poglavje 5.1).
English: With Ryzodeg, hypersensitivity (manifested with swelling of tongue and lips, diarrhoea, nausea, tiredness and itching) and urticaria were reported rarely.
Slovenian: Pri zdravilu Ryzodeg so o preobčutljivosti (ki se kaže v obliki otekanja jezika in ustnic, driske, navzeje, utrujenosti in srbenja) in urtikariji poročali redko.
English: Based on results from clinical trials, the frequency, type and severity of adverse reactions observed in the elderly and in patients with renal or hepatic impairment do not indicate any differences to the broader experience in the general population.
Slovenian: Pogostnost, vrsta in izrazitost neželenih učinkov, opaženih pri starostnikih in bolnikih z okvaro ledvic ali jeter na podlagi kliničnih izkušenj ne kažejo razlik v primerjavi s širšimi izkušnjami v splošni populaciji.
English: Ryzodeg has a rapid onset of action occurring soon after injection providing mealtime coverage while the basal component has a flat and stable action profile providing continuous coverage of the basal insulin requirements.
Slovenian: Zdravilo Ryzodeg začne delovati hitro po injiciranju in krije potrebo po insulinu ob obrokih, bazalna sestavina pa ima enakomeren in stabilen profil delovanja, ki zagotavlja stalno kritje potreb po bazalnem insulinu.
English: 3 Confirmed hypoglycaemia was defined as episodes confirmed by plasma glucose < 3.1 mmol/L or by the patient needing third party assistance.
Slovenian: 3 Potrjena hipoglikemija je bila opredeljena kot potrjena koncentracija glukoze v plazmi < 3,1 mmol/l ali potreba po pomoči druge osebe.
English: Difference: -1.14 [-1.53;-0.76]
Slovenian: Razlika: -1,14 [-1,53;-0,76]
English: drink alcohol; use too much insulin; exercise more than usual; eat too little or miss a meal.
Slovenian: Prenizek krvni sladkor se vam lahko pojavi, če: pijete alkohol, uporabite preveč insulina, ste telesno bolj dejavni kot ponavadi, premalo jeste ali izpustite obrok.
English: There are no clinically relevant differences in the pharmacokinetics of Ryzodeg between elderly and younger adult patients, between races or between healthy subjects and patients with renal or hepatic impairment.
Slovenian: Med starejšimi in mlajšimi odraslimi bolniki, med rasami ter med zdravimi osebami in bolniki z okvaro ledvic ali jeter ni klinično pomembnih razlik v farmakokinetiki.
English: Total exposure with Ryzodeg increases proportionally with increasing dose of the basal component (insulin degludec) and the mealtime component (insulin aspart) in type 1 and type 2 diabetes mellitus.
Slovenian: Celotna izpostavljenost se pri zdravilu Ryzodeg povečuje sorazmerno povečevanju odmerka bazalne sestavine (insulina degludek) in sestavine ob obrokih (insulina aspart); to velja pri sladkorni bolezni tipa 1 in tipa 2.
English: Changing where you inject each time may reduce the risk of developing these skin changes.
Slovenian: Menjavanje mesta injiciranja pri vsaki injekciji pomaga zmanjšati tveganje za nastanek takšnih kožnih sprememb.
English: Ryzodeg can be administered once daily at mealtime in combination with short-/rapid-acting insulin at the remaining meals.
Slovenian: Zdravilo Ryzodeg se lahko uporablja enkrat na dan v času obroka v kombinaciji s kratko/hitrodelujočim insulinom, apliciranim ob preostalih obrokih.
English: Elderly, race, renal and hepatic impairment
Slovenian: Starostniki, rasa, okvara ledvic ali jeter
English: Pack sizes of 1 (with or without needles), 5 (without needles) and multipack of 10 (2 x 5) (without needles) pre-filled pens of 3 mL.
Slovenian: Pakiranja z 1 (z iglami ali brez), s 5 (brez igel) in skupno pakiranje z 10 (2 x 5, brez igel) napolnjenimi injekcijskimi peresniki po 3 ml.
English: Glycerol, metacresol, phenol, sodium chloride, zinc acetate, hydrochloric acid and sodium hydroxide (for pH adjustment) and water for injections
Slovenian: glicerol, metakrezol, fenol, natrijev klorid, cinkov acetat, klorovodikovo kislino in natrijev hidroksid (za uravnavanje pH) in vodo za injekcije.
English: Skin and subcutaneous tissue disorders
Slovenian: Bolezni kože in podkožja neznana lipodistrofija
English: Ryzodeg is presented as a clear and colourless solution for injection in a cartridge (300 units per 3 mL).
Slovenian: Zdravilo Ryzodeg je na voljo kot bistra in brezbarvna raztopina za injiciranje v napolnjenem injekcijskem peresniku (300 enot v 3 ml).
English: Glucose monitoring is to be intensified and the insulin dose adjusted on an individual basis (see section 5.2).
Slovenian: Koncentracijo glukoze v krvi starostnikov je treba spremljati pozorneje ter odmerek insulina individualno prilagoditi (glejte poglavje 5.2).
English: As Ryzodeg contains a rapid-acting mealtime insulin (insulin aspart), prandial glycaemic control at the dosing meal is improved relative to administering basal insulin only; see trial results in Table 1.
Slovenian: Ker zdravilo Ryzodeg vsebuje tudi hitrodelujoči insulin, ki se uporablja med obroki (insulin aspart), je bila prandialna urejenost glikemije med obrokom, ko so si aplicirali insulin, boljša z zdravilom Ryzodeg v primerjavi z bazalnim insulinom; glejte rezultate preskušanj v preglednici 1.
English: The blood glucose-lowering effect of insulin is due to the facilitated uptake of glucose following the binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.
Slovenian: Insulin zniža koncentracijo glukoze v krvi, tako da olajša njen privzem po vezavi insulina na receptorje na mišičnih in maščobnih celicah in hkrati zavre sproščanje glukoze iz jeter.
English: There is no clinical experience with Ryzodeg during breast-feeding.
Slovenian: Kliničnih izkušenj z uporabo zdravila Ryzodeg med dojenjem ni.
English: You will need it after the injection, to correctly remove the needle from the pen.
Slovenian: Potrebovali ga boste za pravilno odstranitev igle z injekcijskega peresnika po injiciranju.
English: Ryzodeg is used to treat diabetes mellitus in adults, adolescents and children from the age of 2 years.
Slovenian: Zdravilo Ryzodeg se uporablja za zdravljenje sladkorne bolezni pri odraslih, mladostnikih in otrocih,
English: Pack sizes of 5 and 10 cartridges.
Slovenian: Pakiranja s 5 ali z 10 vložki.
English: Favours insulin degludec
Slovenian: V prid insulinu degludek
English: 5 After your injection • Lead the needle tip into the outer needle cap on a flat surface without touching the needle or the outer needle cap.
Slovenian: • Konico igle vstavite v zunanji pokrovček igle na ravni površini, ne da bi se dotaknili igle ali zunanjega pokrovčka igle.
English: Ryzodeg may be associated with higher occurrence of severe hypoglycaemia compared to a basal-bolus regimen in the paediatric population, particularly in children 2 to 5 years old (see section 5.1).
Slovenian: Izjema je večja pojavnost hude hipoglikemije v primerjavi z bazalno-bolusno shemo odmerjanja pri pediatrični populaciji, še posebej pri otrocih, starih od 2 do 5 let (glejte poglavja 4.2,