FrancophonIA/ELRC3.0 huggingface dataset:
English: Liraglutide also significantly reduced the risk of expanded MACE (primary MACE, unstable angina pectoris leading to hospitalisation, coronary revascularisation, or hospitalisation due to heart failure) and other secondary endpoints (Figure 2).
Slovenian: Liraglutid je pomembno zmanjšal tudi tveganje za razširjene pomembne srčno-žilne neželene dogodke (primarni pomembni srčno-žilni neželeni dogodki, nestabilna angina pektoris, zaradi katere je potrebna hospitalizacija, koronarna revaskularizacija ali hospitalizacija zaradi srčnega popuščanja) ter druge sekundarne opazovane dogodke (slika 2).
English: Pull off the paper tab from a new disposable needle.
Slovenian: Odstranite papirno nalepko z nove igle za enkratno uporabo.
English: This reduces the risk of contamination, infection, leakage of liraglutide, blocked needles and inaccurate dosing.
Slovenian: Tako zmanjšate tveganje za kontaminacijo, okužbo, puščanje liraglutida, zamašitev igel in netočno odmerjanje.
English: The warning signs of low blood sugar may come on suddenly and can include: cold sweat, cool pale skin, headache, fast heartbeat, feeling sick, feeling very hungry, changes in vision, feeling sleepy, feeling weak, nervous, anxious, confused, difficulty concentrating, shaking (tremor).
Slovenian: • hipoglikemija (nizek krvni sladkor); opozorilni znaki nizkega krvnega sladkorja se lahko pojavijo nenadoma in lahko obsegajo: hladno znojenje, hladno in bledo kožo, glavobol, hitro bitje srca, občutek slabosti v želodcu, hudo lakoto, spremembe vida, zaspanost, šibkost,
English: Liraglutide exposure increased proportionally with dose.
Slovenian: Izpostavljenost liraglutidu se je povečevala sorazmerno z odmerkom.
English: Data from clinical trials showed that liraglutide is associated with delayed gastric emptying.
Slovenian: Podatki iz kliničnih preskušanj so pokazali, da je uporaba liraglutida povezana z zakasnelim praznjenjem želodca.
English: Liraglutide action is mediated via a specific interaction with GLP-1 receptors, leading to an increase in cyclic adenosine monophosphate (cAMP).
Slovenian: Liraglutid deluje s specifičnim učinkom na receptorje GLP-1 in tako povzroči porast cikličnega adenozin monofosfata (cAMP).
English: Blood glucose self-monitoring is necessary to adjust the dose of sulfonylurea and insulin, particularly when Victoza therapy is started and insulin is reduced.
Slovenian: Samokontrola glukoze v krvi pa je potrebna za prilagajanje odmerka sulfonilsečnine in insulina, zlasti ob začetku zdravljenja z zdravilom Victoza in zmanjšanju odmerka insulina.
English: Over the duration of the phase 3a trials, liraglutide decreased the systolic blood pressure on average of 2.3 to 6.7 mmHg from baseline and compared to active comparator the decrease was 1.9 to 4.5 mmHg.
Slovenian: V času trajanja preskušanj faze 3a je liraglutid znižal sistolični krvni tlak v povprečju za 2,3 do 6,7 mm Hg v primerjavi z izhodiščem in za 1,9 do 4,5 mm Hg v primerjavi z aktivno primerjalno učinkovino.
English: Treatment with liraglutide alone and in combination with one or two oral antidiabetic drugs resulted in a reduction in fasting plasma glucose of 13-43.5 mg/dl (0.72-2.42 mmol/l).
Slovenian: Zdravljenje z liraglutidom samim in skupaj z enim ali dvema peroralnima antidiabetikoma je zmanjšalo koncentracijo glukoze v plazmi na tešče za 13-43,5 mg/dl (0,72-2,42 mmol/l).
English: No dose adjustment of lisinopril is required based on these results.
Slovenian: Prilagoditev odmerka lizinoprila na podlagi teh rezultatov ni potrebna.
English: NN:
Slovenian: SN: NN:
English: These tumours were not seen in monkeys treated for 20 months.
Slovenian: Teh tumorjev niso opazili pri opicah, ki so jih zdravili
English: Other medicines and Victoza
Slovenian: Druga zdravila in zdravilo Victoza
English: Victoza can be administered with needles up to a length of 8 mm and as thin as 32G.
Slovenian: Zdravilo Victoza je mogoče injicirati z iglo dolžine do 8 mm in ne tanjšimi kot 32G.
English: Pull off the outer needle cap and keep it for later.
Slovenian: Snemite zunanji pokrovček igle in ga shranite za pozneje.
English: Turn the dose selector until the flow check symbol lines up with the pointer.
Slovenian: Vrtite izbirnik odmerka, dokler ni simbol za preverjanje pretoka poravnan s kazalnikom.
English: If you are also taking a sulfonylurea (such as glimepiride or glibenclamide) or insulin, your doctor may tell you to test your blood sugar levels.
Slovenian: Če hkrati jemljete tudi sulfonilsečnino (na primer glimepirid ali glibenklamid) ali insulin, vam bo zdravnik morda naročil, da si merite koncentracijo krvnega sladkorja.
English: The GLP-1 receptor is the target for native GLP-1, an endogenous incretin hormone that potentiates glucose-dependent insulin secretion from the pancreatic beta cells.
Slovenian: Receptor za GLP-1 je tarča naravnega GLP-1: to je endogen inkretinski hormon, ki od glukoze odvisno poveča izločanje insulina iz celic beta trebušne slinavke.
English: Dosing with Victoza during mid-gestation caused a reduction in maternal weight and foetal growth with equivocal effects on ribs in rats and skeletal variation in the rabbit.
Slovenian: Uporaba zdravila Victoza v srednjem obdobju gestacije je povzročila zmanjšanje materine telesne mase in zastoj rasti ploda, nejasen vpliv pa se je pokazal tudi na rebra podgan ter na spreminjanje skeleta pri kuncih.
English: Pancreatitis can be a serious, potentially life-threatening medical condition.
Slovenian: • vnetje trebušne slinavke (pankreatitis); pankreatitis je lahko resna in potencialno življenjsko ogrožajoča bolezen.
English: Patients treated with liraglutide should be advised of the potential risk of dehydration in relation to gastrointestinal side effects and take precautions to avoid fluid depletion.
Slovenian: Bolnike, ki se zdravijo z liraglutidom, je treba seznaniti z možnimi tveganji dehidracije, povezane z neželenimi učinki na prebavilih, in s previdnostnimi ukrepi za preprečitev pomanjkanja tekočine.
English: • Keep your pen out of the reach of others, especially children.
Slovenian: • Injekcijski peresnik hranite nedosegljivo drugim osebam, še posebej otrokom.
English: The exposure of liraglutide decreases with increasing body weight.
Slovenian: Izpostavljenost liraglutidu se s povečevanjem telesne mase zmanjšuje.
English: The primary endpoint was the time from randomisation to first occurrence of any major adverse cardiovascular events (MACE): CV death, non-fatal myocardial infarction or non-fatal stroke.
Slovenian: Primarni opazovani dogodek je bil čas od randomizacije do prvega pojava katerega od pomembnih srčno-žilnih neželenih dogodkov (Major Adverse Cardiovascular Events (MACE)): smrt zaradi srčnožilnih zapletov, miokardni infarkt brez smrtnega izida ali možganska kap brez smrtnega izida.
English: In mouse models of atherosclerosis, liraglutide prevented aortic plaque progression and reduced inflammation in the plaque.
Slovenian: V modelih ateroskleroze pri miših je liraglutid preprečil napredovanje plaka v aorti in zmanjšal vnetje v plaku.
English: Both improvement of glycaemic control and reduction of cardiovascular morbidity and mortality are an integral part of the treatment of type 2 diabetes.
Slovenian: Tako izboljšanje uravnavanja glikemije kot zmanjšanje obolevnosti in umrljivosti zaradi srčno-žilnih dogodkov sta bistvena dela zdravljenja sladkorne bolezni tipa 2.
English: This will help your doctor to decide if the dose of the sulfonylurea or insulin needs to be changed.
Slovenian: Tako se bo vaš zdravnik lažje odločil, če morate spremeniti odmerek sulfonilsečnine ali insulina.
English: • Allergic reactions like pruritus (itching) and urticaria (a type of skin rash)
Slovenian: • alergijske reakcije, kot sta pruritus (srbečica) in koprivnica (vrsta kožnega izpuščaja)
English: Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.
Slovenian: V razvrstitvah pogostnosti so neželeni učinki navedeni po padajoči resnosti.
English: This medicine is not recommended if you have a severe stomach or gut problem which results in delayed stomach emptying (called gastroparesis), or inflammatory bowel disease.
Slovenian: Uporaba tega zdravila ni priporočljiva, če imate hude težave z želodcem ali črevesjem in se vam zato želodec počasneje prazni (gastropareza) ali če imate kronično vnetno črevesno bolezen.
English: Prepare your pen Check the name and coloured label of your pen to make sure that it contains liraglutide.
Slovenian: Preverite ime in barvo nalepke injekcijskega peresnika in se tako prepričajte, da vsebuje liraglutid.
English: The mean HbA1c at baseline was 8.7% for liraglutide and placebo.
Slovenian: V izhodišču je bila povprečna vrednost HbA1c 8,7 % pri liraglutidu in placebu.
English: When you first start using these medicines together, your doctor may tell you to lower the dose of the sulfonylurea or insulin.
Slovenian: Ko začnete hkrati jemati ti dve zdravili, vam bo morda zdravnik naročil, da zmanjšate odmerek zdravila, ki vsebuje sulfonilsečnino ali insulin.
English: • Postprandial glucose
Slovenian: • Postprandialna koncentracija glukoze
English: • Increase of pancreatic enzymes (such as lipase and amylase).
Slovenian: • zvišanje koncentracije encimov trebušne slinavke (npr. lipaze in amilaze)
English: The mechanism of blood glucose lowering also involves a minor delay in gastric emptying.
Slovenian: Mehanizem zniževanja glukoze v krvi vključuje tudi manjšo upočasnitev praznjenja želodca.
English: When the pen is empty, carefully dispose of it without a needle attached.
Slovenian: Ko je injekcijski peresnik prazen, ga pazljivo zavrzite brez nameščene igle.
English: If the dose selector stops before 0.6 mg lines up with the pointer, prepare a new pen and inject the full dose with the new pen.
Slovenian: Če se izbirnik odmerka ustavi, preden se s kazalnikom poravna odmerek 0,6 mg, pripravite nov injekcijski peresnik in z njim injicirajte celotni odmerek.
English: ≤5.5 mmol/l (≤100 mg/dl) Target
Slovenian: ≤ 5,5 mmol/l (≤ 100 mg/dl) cilj brez prilagoditve
English: If a patient wishes to become pregnant, or pregnancy occurs, treatment with Victoza should be discontinued.
Slovenian: Če želi bolnica zanositi ali če zanosi, prekinite zdravljenje z zdravilom Victoza.
English: On the basis of the scientific conclusions for liraglutide the CHMP is of the opinion that the benefitrisk balance of the medicinal product(s) containing liraglutide is unchanged subject to the proposed changes to the product information
Slovenian: Podlaga za spremembe pogojev dovoljenja (dovoljenj) za promet z zdravilom Na podlagi znanstvenih zaključkov za liraglutid odbor CHMP meni, da je razmerje med koristjo in tveganjem zdravil(-a), ki vsebuje(-jo) liraglutid, nespremenjeno ob upoštevanju predlaganih sprememb v informacijah o zdravilu.
English: The most frequent adverse reactions leading to withdrawal for liraglutide-treated patients were nausea (2.8% of patients) and vomiting (1.5%).
Slovenian: Najpogostejša neželena učinka, zaradi katerih je bilo zdravljenje z liraglutidom prekinjeno, sta bila navzea (2,8 % bolnikov) in bruhanje (1,5 %).
English: • Do not share your pen or needles with anyone else.
Slovenian: • Injekcijskega peresnika ali igel ne delite z drugimi.
English: The patient should be advised to discard the injection needle in accordance with local requirements after each injection and store the pen without an injection needle attached.
Slovenian: Bolnika opozorite, naj po vsakem injiciranju zdravila injekcijsko iglo zavrže v skladu z lokalnimi predpisi in shrani injekcijski peresnik brez nameščene igle.
English: Gastrointestinal adverse events were more frequently reported with liraglutide treatment (43.6% vs 37.1%).
Slovenian: Neželeni učinki na prebavilih so bili pogosteje poročani pri zdravljenju z liraglutidom (43,6 % v primerjavi s 37,1 %).
English: Low blood sugar (hypoglycaemia) may reduce your ability to concentrate.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Nizek krvni sladkor (hipoglikemija) lahko zmanjša vašo zmožnost koncentracije.
English: No other treatment-related tumours have been found.
Slovenian: Drugih tumorjev, povezanih z zdravljenjem s tem zdravilom, niso ugotovili.
English: There was a small increase in the rate of minor hypoglycaemic episodes (0.23 versus 0.03 events per patient years).
Slovenian: Ugotovili so manjše povečanje deleža blagih hipoglikemičnih epizod (0,23 v primerjavi z 0,03 dogodka na bolnik-let).
English: Use of liraglutide is not recommended in these patients since it is associated with transient gastrointestinal adverse reactions, including nausea, vomiting and diarrhoea.
Slovenian: Uporaba liraglutida pri teh bolnikih ni priporočljiva, saj je povezana s prehodnimi neželenimi učinki na prebavilih, vključno z navzeo, bruhanjem in drisko.
English: Victoza is administered once daily at any time, independent of meals, and can be injected subcutaneously in the abdomen, in the thigh or in the upper arm.
Slovenian: Zdravilo Victoza je treba aplicirati enkrat na dan ob kateri koli uri, ne glede na obroke, injicira pa se lahko subkutano v predel trebuha, stegno ali nadlaket.
English: The mean clearance following subcutaneous administration of a single dose liraglutide is approximately 1.2 l/h with an elimination half-life of approximately 13 hours.
Slovenian: Povprečen očistek po subkutani aplikaciji enkratnega odmerka liraglutida je približno 1,2 l/h, eliminacijski razpolovni čas pa je približno 13 ur.
English: In the LEADER study, delayed gastric emptying was reported three times more frequently in the liraglutide group compared to the placebo group.
Slovenian: V študiji LEADER so pri skupini preiskovancev, ki je prejemala liraglutid, trikrat pogosteje poročali o zakasnelem praznjenju želodca kot pri skupini, ki je prejemala placebo.
English: Non-clinical data reveal no special hazards for humans based on conventional studies of safety pharmacology, repeat-dose toxicity or genotoxicity.
Slovenian: Neklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih in genotoksičnosti ne kažejo posebnega tveganja za človeka.
English: • Injection site reactions (such as bruising, pain, irritation, itching and rash)
Slovenian: • reakcije na mestu injiciranja (npr. podplutbe, bolečina, draženje, srbenje in izpuščaj)
English: If the dose selector stops before your needed dose lines up with the pointer, there is not enough liraglutide left for a full dose.
Slovenian: Če se izbirnik odmerka ustavi, preden se želeni odmerek poravna s kazalnikom, to pomeni, da ni več dovolj liraglutida za celotni odmerek.
English: The CHMP recommends that the terms of the marketing authorisation should be varied.
Slovenian: Odbor CHMP zato priporoča spremembo pogojev dovoljenja (dovoljenj) za promet z zdravilom.
English: The HR for liraglutide vs placebo was 0.78 [0.67, 0.92] for time to first nephropathy event and 1.15 [0.87, 1.52] for time to first retinopathy event.
Slovenian: Razmerje ogroženosti za liraglutid v primerjavi s placebom je bilo 0,78 [0,67, 0,92] pri času do prvega dogodka nefropatije in 1,15 [0,87, 1,52] pri času do prvega dogodka retinopatije.
English: In rats, a no observed adverse effect level (NOAEL) was not observed.
Slovenian: (NOAEL - No Observed Adverse Effect Level).
English: Some patients are expected to benefit from an increase in dose from 1.2 mg to 1.8 mg and based on clinical response, after at least one week, the dose can be increased to 1.8 mg to further improve glycaemic control.
Slovenian: Po vsaj enem tednu je treba odmerek povečati na 1,2 mg. Nekaterim bolnikom lahko koristi povečanje odmerka z 1,2 mg na 1,8 mg; glede na klinični odziv je mogoče odmerek po vsaj enem tednu zdravljenja povečati na 1,8 mg za dodatno izboljšanje urejenosti glikemije.
English: No data are available for children below 10 years of age (see sections 5.1 and 5.2).
Slovenian: let, podatki niso na voljo (glejte poglavji 5.1 in 5.2).
English: Cartridge (type 1 glass) with a plunger (bromobutyl) and a laminate rubber sheet (bromobutyl/polyisoprene) contained in a pre-filled multidose disposable pen made of polyolefin and polyacetal.
Slovenian: Vložek (steklo tipa I) z batom (brombutil) in laminatno gumijasto prevleko (brombutil/poliizopren) v večodmernem napolnjenem injekcijskem peresniku za enkratno uporabo iz poliolefina in poliacetala.
English: The small delay of gastric emptying with liraglutide may influence absorption of concomitantly administered oral medicinal products.
Slovenian: Rahla upočasnitev pri praznjenju želodca pri zdravljenju z liraglutidom lahko vpliva na absorpcijo sočasno uporabljenih peroralnih zdravil.
English: Titration of the insulin glargine dose was managed by the patient after instruction by the investigator:
Slovenian: Odmerek insulina glargin je prilagajal bolnik po navodilih raziskovalca.
English: Patients receiving liraglutide in combination with a sulfonylurea or insulin may have an increased risk of hypoglycaemia (see section 4.8).
Slovenian: Bolniki, ki dobivajo liraglutid skupaj s sulfonilsečnino ali insulinom, imajo lahko večje tveganje za hipoglikemijo (glejte poglavje 4.8).
English: If you forget to use Victoza
Slovenian: Če ste pozabili uporabiti zdravilo Victoza
English: Novo Nordisk A/S Hallas Allé DK-4400 Kalundborg Denmark
Slovenian: DK-4400 Kalundborg Danska
English: Be careful not to touch the display with your other fingers or press the dose selector sideways when you inject.
Slovenian: Pazite, da se med injiciranjem z drugimi prsti ne boste dotaknili zaslona ali izbirnika odmerka potisnili vstran.
English: In both groups a decrease in body weight was seen: -2.4 kg with liraglutide vs -1.09 kg with placebo.
Slovenian: V obeh skupinah so ugotovili zmanjšanje telesne mase; -2,4 kg z liraglutidom in -1,09 kg s placebom.
English: After first use: Store below 30°C or store in a refrigerator (2°C-8°C).
Slovenian: Po prvi uporabi: Shranjujte pri temperaturi do 30 °C ali shranjujte v hladilniku (2 °C - 8 °C).
English: Generally, the patients reported severe nausea, vomiting and diarrhoea.
Slovenian: Večinoma so bolniki poročali o hudi navzeji, bruhanju in driski.
English: Your doctor may reduce your dose of these medicines before you start using Victoza.
Slovenian: Zdravnik lahko pred uvedbo zdravljenja z zdravilom Victoza odmerek teh zdravil zmanjša.
English: Following a [3H]-liraglutide dose, intact liraglutide was not detected in urine or faeces.
Slovenian: Po odmerku [3H]-liraglutida v urinu ali blatu ni bilo nespremenjenega liraglutida.
English: In a 104-week clinical trial, 57% of patients with type 2 diabetes treated with insulin degludec in combination with metformin achieved a target HbA1c <7% and the remaining patients continued in a
Slovenian: V 104-tedenskem kliničnem preskušanju je 57 % bolnikov s sladkorno boleznijo tipa 2 pri zdravljenju z insulinom degludek v kombinaciji z metforminom doseglo ciljno vrednost HbA1c < 7 %.
English: Additional trials were conducted with liraglutide that included 1,901 patients in four unblinded, randomised, controlled clinical trials (including 464, 658, 323 and 177 patients per trial) and one double-blind, randomised, controlled clinical trial in patients with type 2 diabetes mellitus and moderate renal impairment (279 patients).
Slovenian: Z liraglutidom so opravili dodatna štiri slepa, randomizirana, kontrolirana klinična preskušanja s skupno 1.901 bolnikom (v posameznih preskušanjih je bilo vključenih 464, 658, 323 oz. 177 bolnikov) in eno dvojno slepo, randomizirano, kontrolirano klinično preskušanje pri bolnikih s sladkorno boleznijo tipa 2 in zmerno okvaro ledvic (vključenih 279 bolnikov).
English: Pack sizes of 1, 2, 3, 5 or 10 pre-filled pens.
Slovenian: V pakiranju je 1, 2, 3, 5 ali 10 napolnjenih injekcijskih peresnikov.
English: Pull off the inner needle cap and dispose of it.
Slovenian: Snemite notranji pokrovček igle in ga zavrzite.
English: As there is sufficient evidence to conclude on a causal relationship between delayed gastric emptying and liraglutide, delayed gastric emptying should be included as an ADR in section 4.8 of the SmPC with a frequency allocation of ‘uncommon' and in section 4 of the Package Leaflet.
Slovenian: Ker je na voljo dovolj dokazov, ki kažejo na vzročno povezanost med zakasnelim praznjenjem želodca in liraglutidom, je treba zakasnelo praznjenje želodca vključiti kot neželeni učinek zdravila v poglavje 4.8 Povzetka glavnih značilnosti zdravila s pogostnostjo ‘občasni', in v poglavje 4
English: There is limited experience in patients with inflammatory bowel disease and diabetic gastroparesis.
Slovenian: Izkušenj pri zdravljenju bolnikov s kronično vnetno črevesno boleznijo in diabetično gastroparezo je malo.
English: Diabetic ketoacidosis has been reported in insulin-dependent patients after rapid discontinuation or dose reduction of insulin (see section 4.2).
Slovenian: Pri bolnikih, odvisnih od insulina, so po hitri ukinitvi ali zmanjšanju odmerka insulina poročali o diabetični ketoacidozi (glejte poglavje 4.2).
English: • Cardiovascular evaluation
Slovenian: • Vrednotenje srčno-žilnega sistema
English: The safety profile of liraglutide in combination with premix insulin was overall comparable to that observed for placebo in combination with premix insulin (see section 4.8).
Slovenian: Varnostni profil kombinacije liraglutida in pripravljene mešanice insulina je bil v celoti primerljiv z varnostnim profilom kombinacije placeba in pripravljene mešanice insulina (glejte poglavje 4.8).
English: Be careful not to press the dose button when turning the dose selector backwards, as liraglutide may come out.
Slovenian: Pazite, da ne boste med vrtenjem izbirnika odmerka pritisnili na potisni gumb, ker bi s tem lahko iztisnili liraglutid.
English: Additional components in expanded MACE: Unstable angina pectoris (hospitalisation) Coronary revascularisation Heart failure (hospitalisation) Other secondary endpoints:
Slovenian: Dodatne komponente razširjenih MACE: Nestabilna angina pektoris (hospitalizacija)
English: Name and address of the manufacturer responsible for batch release
Slovenian: Ime in naslov proizvajalca, odgovornega za sproščanje serij
English: - The other ingredients are disodium phosphate dihydrate, propylene glycol, phenol and water for injections.
Slovenian: - Druge sestavine zdravila so natrijev hidrogenfosfat dihidrat, propilenglikol, fenol in voda za injekcije.
English: Simultaneously, liraglutide lowers inappropriately high glucagon secretion, also in a glucose-dependent manner.
Slovenian: Hkrati liraglutid zmanjšuje neprimerno veliko izločanje glukagona, prav tako odvisno od koncentracije glukoze.
English: When initiating treatment with Victoza, you may in some cases experience loss of fluids/dehydration, e.g. in case of vomiting, nausea and diarrhoea.
Slovenian: Po uvedbi zdravljenja z zdravilom Victoza se lahko v nekaterih primerih pojavi izguba tekočine (dehidracija), npr. v primeru bruhanja, siljenja na bruhanje in driske.
English: The rate of hypoglycaemic episodes (per patient year of exposure) was statistically significantly lower when adding liraglutide compared to adding a single dose of insulin aspart (1.0 vs 8.15; ratio: 0.13; 95% CI: 0.08 to 0.21).
Slovenian: Pri dodatku liraglutida je bil delež hipoglikemičnih epizod (na bolnik-let izpostavljenosti) statistično pomembno manjši kot pri dodatku enega odmerka insulina aspart (1,0 v primerjavi z 8,15; razmerje: 0,13; 95 % IZ: 0,08 do 0,21).
English: Liraglutide exposure was decreased by 13-23% in patients with mild to moderate hepatic impairment compared to healthy subjects.
Slovenian: Izpostavljenost liraglutidu je bila pri bolnikih z blago do zmerno okvaro jeter za 13-23 % manjša kot pri zdravih osebah.
English: Insert the needle into your skin using the injection technique shown by your doctor or nurse.
Slovenian: Iglo zabodite v kožo tako, kot sta vam pokazala zdravnik ali medicinska sestra.
English: A single dose administration of digoxin 1 mg with liraglutide resulted in a reduction of digoxin AUC by 16%; Cmax decreased by 31%.
Slovenian: Enkratni odmerek 1 mg digoksina skupaj z liraglutidom je zmanjšal AUC digoksina za 16 % ter Cmax za 31 %.
English: What Victoza looks like and contents of the pack
Slovenian: Izgled zdravila Victoza in vsebina pakiranja