FrancophonIA/ELRC3.0 huggingface dataset:
English: For more information about treatment with Ryzodeg, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Croatian: Više informacija o liječenju lijekom Ryzodeg pročitajte u uputi o lijeku (također dio EPAR-a), odnosno obratite se svom liječniku ili ljekarniku.
English: What is Ryzodeg?
Croatian: Što je Ryzodeg?
English: It is available as a solution for injection in a cartridge (100 units/ml) and in a pre-filled pen (100 units/ml).
Croatian: Dostupan je kao otopina za injekciju u ulošku (100 jedinica/ml) i za injekciju u napunjenoj brizgalici (100 jedinica/ml).
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Ryzodeg have been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Ryzodeg nalaze se u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: The Committee concluded that Ryzodeg is generally safe and its side effects are comparable to those of other insulin analogues.
Croatian: Odbor je zaključio da je lijek Ryzodeg općenito siguran i da su njegove nuspojave usporedive s nuspojavama ostalih inzulinskih analoga.
English: What is the risk associated with Ryzodeg?
Croatian: Koji su rizici povezani s lijekom Ryzodeg?
English: Meanwhile, insulin aspart is absorbed faster by the body than human insulin, and therefore it starts to work as soon as it is injected and has a short duration of action.
Croatian: Pritom tijelo brže apsorbira aspart inzulin u odnosu na humani inzulin i stoga počinje djelovati čim ga se ubrizga i ima kratko djelovanje.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Ryzodeg.
Croatian: Objašnjava kako je Odbor za lijekove za humanu uporabu (CHMP) ocijenio lijek da bi donio svoje mišljenje u korist izdavanja odobrenja za stavljanje lijeka u promet te preporuke o uvjetima za primjenu lijeka Ryzodeg.
English: By controlling the level of blood glucose, the symptoms and complications of diabetes are reduced.
Croatian: Kontrolirajući razinu glukoze u krvi smanjuju se simptomi i komplikacije šećerne bolesti.
English: Diabetes is a disease in which the body does not produce enough insulin to control the level of blood sugar or when the body is unable to use insulin effectively.
Croatian: Šećerna bolest je bolest kod koje tijelo ne proizvodi dovoljno inzulina kako bi kontroliralo razinu šećera u krvi ili kada tijelo nije u stanju učinkovito koristiti inzulin.
English: This is a summary of the European public assessment report (EPAR) for Ryzodeg.
Croatian: Ovo je sažetak europskoga javnog izvješća o ocjeni dokumentacije o lijeku (EPAR) za lijek Ryzodeg.
English: Insulin degludec and insulin aspart are slightly different from human insulin.
Croatian: Degludek inzulin i aspart inzulin malo su drugačiji od humanog inzulina.
English: The place for injection should be altered with each injection to reduce the risk of developing fatty lumps under the skin that can affect the amount of Ryzodeg absorbed into the blood.
Croatian: Mjesto ubrizgavanja mora biti drugačije kod primjene svake injekcije kako bi se smanjio rizik od nastanka potkožnog masnog tkiva koje može utjecati na količinu lijeka Ryzodeg koja se apsorbira u krv.
English: The active substances in Ryzodeg, insulin degludec and insulin aspart, are produced by a method known as ‘recombinant DNA technology': they are made by a yeast that has received a gene (DNA), which makes the yeast able to produce them.
Croatian: Djelatne tvari u lijeku Ryzodeg, degludek inzulin i aspart inzulin, proizvode se metodom poznatom kao tehnologija „rekombinantne DNK”: stvara se putem bakterije koja je primila gen (DNK) što joj omogućuje stvaranje navedenih djelatnih tvari.
English: Ryzodeg insulin degludec / insulin aspart
Croatian: Ryzodeg degludek inzulin/aspart inzulin
English: What benefit has Ryzodeg shown during the studies?
Croatian: Koje su koristi lijeka Ryzodeg dokazane u ispitivanjima?
English: The reduction in HbA1c levels (in percentage points) was 0.7 in patients with type 1 diabetes and between 1 and 1.7 across the trials in patients with type 2 diabetes.
Croatian: 2. Smanjenje razina HbA1c (u postocima) iznosilo je 0,7 u bolesnika sa šećernom bolesti tipa 1 i između 1 i 1,7 u ispitivanjima provedenima na bolesnicima sa šećernom bolesti tipa 2.
English: The most frequently reported side effect during treatment with Ryzodeg is hypoglycaemia (low blood glucose levels).
Croatian: Najčešće prijavljena nuspojava tijekom liječenja lijekom Ryzodeg je hipoglikemija (niske razine glukoze u krvi).
English: Ryzodeg is used to treat diabetes in adults, adolescents and children from 2 years of age.
Croatian: Ryzodeg se koristi za liječenje šećerne bolesti u odraslih, adolescenata i djece od navršene 2. godine života.
English: All of the studies measured the level of glycosylated haemoglobin (HbA1c), which is the percentage of haemoglobin in the blood attached to glucose.
Croatian: Sva su ispitivanja mjerila razinu tvari u krvi zvanu glikolizirani hemoglobin (HbA1c) koji predstavlja postotak hemoglobina u krvi na kojeg je vezana glukoza.
English: In the study in children, the combined used of Ryzodeg and insulin aspart was at least as effective as insulin detemir and insulin aspart, with average HbA1c reductions of 0.27 and 0.23 percentage points respectively.
Croatian: U ispitivanjima provedenima na djeci kombinirana primjena lijeka Ryzodeg i aspart inzulina bila je barem podjednako djelotvorna kao primjena detemir inzulina i aspart inzulina, uz prosječna smanjenja HbA1c od 0,27 i 0,23 posto.
English: The replacement insulin acts in the same way as natural insulin, and helps glucose from the blood to enter cells.
Croatian: Zamjenski inzulin djeluje na isti način kao prirodni inzulin i pomaže glukozi u krvi da uđe u stanice.
English: The CHMP decided that Ryzodeg's benefits are greater than its risks and recommended that it be given marketing authorisation.
Croatian: CHMP je odlučio da koristi od lijeka Ryzodeg nadmašuju s njim povezane rizike te je preporučio izdavanje odobrenja za stavljanje lijeka u promet.
English: Why has Ryzodeg been approved?
Croatian: Zašto je lijek Ryzodeg odobren?
English: Ryzodeg was given once a day at mealtime with insulin aspart given at other mealtimes and this treatment was compared with treatment comprising insulin detemir given once or twice a day with insulin aspart given at all mealtimes.
Croatian: Ryzodeg je primjenjivan jednom dnevno uz obrok, a aspart inzulin uz ostale obroke, i to je liječenje uspoređeno s liječenjem koje se sastoji od primjene detemir inzulina jednom ili dvaput dnevno zajedno s aspart inzulinom primjenjivanim uz sve obroke.
English: In the studies in type 2 diabetes, Ryzodeg was either given alone or in combination with other antidiabetes medicines.
Croatian: U ispitivanjima šećerne bolesti tipa 2 lijek Ryzodeg primjenjivan je ili samostalno ili u kombinaciji s ostalim lijekovima za liječenje šećerne bolesti.
English: Injecting Ryzodeg at a main meal provides long-acting insulin to control blood sugar until the next dose as well as short-acting insulin to help deal with the extra sugar from the meal.
Croatian: Ubrizgavanje lijeka Ryzodeg uz glavni obrok osigurava dugodjelujući inzulin koji kontrolira šećer u krvi do primjene sljedeće doze, a kratkodjelujući inzulin pomaže regulirati višak šećera iz obroka.
English: It also noted that in the studies with adults Ryzodeg reduces the risk of hypoglycaemia during the night in patients with type 1 and type 2diabetes.
Croatian: Također je zabilježeno da u ispitivanjima provedenima na odraslima lijek Ryzodeg smanjuje rizik od noćne hipoglikemije u bolesnika sa šećernom bolesti tipa 1 i 2.
English: Ryzodeg is a medicine that contains the active substances insulin degludec and insulin aspart.
Croatian: Ryzodeg je lijek koji sadrži djelatne tvari degludek inzulin i aspart inzulin.
English: What is Ryzodeg used for?
Croatian: Za što se Ryzodeg koristi?
English: The studies in adults showed that Ryzodeg was at least as effective as long-acting insulins and biphasic insulin in controlling blood glucose levels in patients with type 1 and type 2 diabetes.
Croatian: Ispitivanja provedena na odraslima pokazala su da je lijek Ryzodeg bio barem podjednako djelotvoran kao dugodjelujući inzulini i bifazični inzulin za kontrolu razina glukoze u krvi u bolesnika sa šećernom bolesti tipa 1 i tipa
English: The CHMP concluded that Ryzodeg is effective in controlling blood glucose levels in adults, adolescents and children aged over 2 years with diabetes.
Croatian: Odbor za lijekove za humanu uporabu (CHMP) zaključio je da je lijek Ryzodeg djelotvoran u kontroli razina glukoze u krvi u odraslih, adolescenata i djece od navršene 2. godine života sa šećernom bolešću.
English: Ryzodeg is a replacement insulin for the insulin normally made by the body.
Croatian: Ryzodeg je zamjenski inzulin koji se koristi umjesto inzulina koji tijelo prirodno proizvodi.
English: Ryzodeg has also been studied in one main study in 362 children aged between 1 and 17 years with type 1 diabetes.
Croatian: Ryzodeg je ispitivan i u glavnom ispitivanju na 362 djece dobi između 1 i 17 godina života sa šećernom bolesti tipa
English: The differences mean that insulin degludec is absorbed more slowly by the body.
Croatian: Razlikuju se u tome što tijelo sporije apsorbira degludek inzulin.
English: In type 1 diabetes, Ryzodeg is used with rapid-acting insulin, which is injected at other mealtimes.
Croatian: Kod šećerne bolesti tipa 1 Ryzodeg se koristi uz brzodjelujući inzulin koji se ubrizgava uz ostale obroke.
English: In the studies in type 1 diabetes, patients also received injections of rapid acting insulin at other mealtimes.
Croatian: U ispitivanjima šećerne bolesti tipa 1 bolesnici su također dobili injekcije brzodjelujućeg inzulina uz ostale obroke.
English: How is Ryzodeg used?
Croatian: Kako se Ryzodeg koristi?
English: How does Ryzodeg work?
Croatian: Kako djeluje Ryzodeg?
English: Ryzodeg has been studied in one main study involving 548 adults with type 1 diabetes and in four main studies involving 1,866 adults with type 2 diabetes.
Croatian: Ryzodeg je ispitivan u okviru glavnog ispitivanja na 584 odrasle osobe sa šećernom bolesti tipa 1 i četiri glavna ispitivanja na 1.866 odraslih osoba sa šećernom bolesti tipa 2. Lijek Ryzodeg primijenjen uz obroke uspoređen je u ispitivanjima s glargin inzulinom ili detemir inzulinom (dugodjelujućim inzulinima), ili sa bifazičnim inzulinom (inzulinski pripravak koji sadrži mješavinu inzulina srednjeg i brzog djelovanja).
English: MA (EU) number (Invented) name Strength Pharmaceutical Form Route of Administration
Croatian: Broj (EU) odobrenja (Zaštićeno) ime Doza Farmaceutski oblik Put primjene Unutarnje pakovanje Veličina pakovanja EU/1/11/745/001
English: However, these conditions are reported more frequently in the younger children in general.
Croatian: Međutim, ta su stanja općenito češće zabilježena u mlađe djece.
English: This effect is considered clinically not relevant.
Croatian: Ovaj se učinak ne smatra klinički relevantnim.
English: Dehydration may be a contributing factor in some of these cases.
Croatian: Dehidracija može doprinijeti nekim od ovih slučajeva.
English: Your doctor or pharmacist will tell you the exact number of sachets and what strength to take at each time.
Croatian: Vaš liječnik ili ljekarnik će Vam reći točan broj vrećica i koje jačine morate uzeti svaki put.
English: Your dose of Translarna depends on your body weight.
Croatian: Vaša doza lijeka Translarna ovisi o Vašoj tjelesnoj težini.
English: There have been cases reported where this increase to abnormal high values was already observed after 4 weeks.
Croatian: Zabilježeni su slučajevi u kojima je porast na abnormalno visoke vrijednosti opažen već nakon 4 tjedna.
English: A standard package of reproduction toxicity studies was available.
Croatian: Dostupan je bio standardni paket ispitivanja reproduktivne toksičnosti.
English: The toxicity of the metabolite is unknown.
Croatian: Toksičnost metabolita nije poznata.
English: Do not take a double dose to make up for a forgotten dose.
Croatian: Ne uzimajte dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: You may have one or more of the following side effects after taking Translarna:
Croatian: Možete imati jednu ili više sljedećih nuspojava nakon uzimanja lijeka Translarna:
English: Other medicines and Translarna
Croatian: Drugi lijekovi i Translarna
English: Tell your doctor if you are taking, have recently taken, or might take any other medicines.
Croatian: Obavijestite svog liječnika ako uzimate ili ste nedavno uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: Ataluren does not distribute into red blood cells.
Croatian: Ataluren se ne distribuira u crvene krvne stanice.
English: Translarna is available in packs containing 30 sachets.
Croatian: Translarna je dostupna u pakiranjima koja sadrže 30 vrećica.
English: Frequency groupings are defined to the following convention: very common (≥ 1/10) and common (≥ 1/100 to < 1/10).
Croatian: Skupine učestalosti definirane su prema sljedećoj konvenciji: vrlo često (≥ 1/10) i često (≥ 1/100 i < 1/10).
English: What Translarna is and what it is used for
Croatian: Što je Translarna i za što se koristi
English: Delayed or missed dose
Croatian: Odgođena ili propuštena doza
English: Characteristic in specific groups of subjects or patients
Croatian: Karakteristike u posebnim skupinama ispitanika ili bolesnika
English: Increasing the dose above the recommended dose may be associated with reduced effectiveness.
Croatian: Povećanje doze iznad preporučene doze može biti povezano sa smanjenom učinkovitosti.
English: Remember to take the next dose on time.
Croatian: Sjetite se uzeti sljedeću dozu na vrijeme.
English: Date of first authorisation: 31 July 2014 Date of latest renewal: 19 July 2018
Croatian: Datum posljednje obnove odobrenja: 19. srpnja 2018.
English: Do not give this medicine to children under the age of 2 years or weighing less than 12 kg as it has not been tested in this group of patients.
Croatian: Nemojte davati ovaj lijek djeci mlađoj od 2 godine ili težine manje od 12 kg, budući da lijek nije ispitan u ovoj skupini bolesnika.
English: Patients should take the entire dose.
Croatian: Bolesnik treba uzeti cijelu dozu.
English: Ataluren should be administered orally every day in 3 doses.
Croatian: Ataluren treba primjenjivati peroralno svaki dan u 3 doze.
English: Check with them if you are not sure.
Croatian: Provjerite s liječnikom ili ljekarnikom ako niste sigurni.
English: Co. Armagh BT63 5UA
Croatian: Armagh BT63 5UA
English: However, the magnitude of this effect could be larger for the 40 mg dose of telmisartan.
Croatian: Međutim, razmjer tog učinka mogao bi biti veći za doze telmisartana od 40 mg.
English: But, take the next doses on time.
Croatian: Ali, sljedeće doze uzmite na vrijeme.
English: Translarna is used to treat patients aged 2 years and older, who are able to walk.
Croatian: Translarna se koristi za liječenje bolesnika u dobi od 2 godine i starijih, koji mogu hodati.
English: Long term safety data is not available.
Croatian: Nisu dostupni podaci o dugoročnoj sigurnosti primjene.
English: Your doctor will monitor your blood pressure every 6 months, if you are taking a corticosteroid medicine.
Croatian: Vaš će liječnik pratiti Vaš krvni tlak mjerenjem svakih 6 mjeseci, ako uzimate lijek koji sadrži kortikosteroid.
English: Translarna may not be as effective in treating your symptoms if you take more than the recommended dose.
Croatian: Lijek Translarna možda neće biti učinkovit u liječenju Vaših simptoma ako uzimate više od preporučene doze.
English: Potential interactions with other medicinal products
Croatian: Moguće interakcije s drugim lijekovima
English: Pack of 30 sachets.
Croatian: Pakiranje od 30 vrećica.
English: Drink water or other liquids regularly to avoid dehydration while taking Translarna.
Croatian: Redovito pijte vodu ili druge tekućine kako biste izbjegli dehidraciju prilikom uzimanja lijeka Translarna.
English: Weight Range (kg)
Croatian: Raspon tjelesne težine (kg)
English: These may affect your kidney function.
Croatian: Ovo može utjecati na funkciju vaših bubrega.
English: The pharmacokinetics of ataluren has been evaluated in study PTC124-GD-030 over a duration of 4 weeks.
Croatian: Farmakokinetika atalurena bila je procijenjena u ispitivanju PTC124-GD-030 u trajanju od 4 tjedna.
English: Patients who do not have a nonsense mutation
Croatian: Bolesnici koji nemaju besmislenu mutaciju
English: In vitro, ataluren is 99.6% bound to human plasma proteins and the binding is independent of plasma concentration.
Croatian: In vitro, ataluren je 99,6% vezan za proteine u ljudskoj plazmi, a vezanje je neovisno o plazmatskim koncentracijama.
English: Higher ataluren exposure was associated with potential decrease in efficacy.
Croatian: Viša izloženost atalurenu bila je povezana s potencijalnim smanjenjem djelotvornosti.
English: Patients should not take a double or extra dose if a dose is missed.
Croatian: Bolesnici ne smiju uzimati dvostruke ili dodatne doze, ako propuste dozu.
English: Very common side effects (may affect more than 1 in 10 people): - Vomiting
Croatian: Vrlo česte nuspojave (mogu se javiti kod više od 1 na 10 osoba): - povraćanje
English: The safety and efficacy of Translarna in children <12kg and aged 6 months to 2 years have not yet been established.
Croatian: Sigurnost i djelotvornost lijeka Translarna u djece < 12 kg i u dobi od 6 mjeseci do 2 godine nisu još ustanovljene.
English: As a precautionary measure, it is recommended to avoid the use of ataluren during pregnancy.
Croatian: Kao mjeru predostrožnosti preporuča se izbjegavanje primjene atalurena tijekom trudnoće.
English: Separation between ataluren and placebo was maintained from Week 16 through the end of the study.
Croatian: Razlika između atalurena i placeba održala se od 16. tjedna do kraja ispitivanja.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton Box
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Kartonska kutija
English: Efficacy has not been demonstrated in non-ambulatory patients.
Croatian: Djelotvornost nije dokazana u nepokretnih bolesnika.
English: The first dose should be taken in the morning, the second at midday, and the third in the evening.
Croatian: Prvu dozu treba uzeti ujutro, drugu u podne, a treću navečer.
English: Tell your doctor if you are taking any of the following medicines:
Croatian: Obavijestite svojeg liječnika ako uzimate bilo koji od niže navedenih lijekova:
English: Take Translarna by mouth 3 times per day; in the morning, midday and evening.
Croatian: Lijek Translarna uzmite kroz usta 3 puta dnevno, ujutro, u podne i navečer.
English: The majority of patients in both treatment groups were Caucasian (76%).
Croatian: Većina bolesnika u obje skupine liječenja bili su bijelci (76%).
English: This medicine has been given ‘conditional approval'.
Croatian: Ovom lijeku izdano je „uvjetno odobrenje“.
English: Percent Not 10% Worsened
Croatian: Postotak bez 10% pogoršanja
English: The majority of patients in all treatment groups were Caucasian (90%).
Croatian: Većina bolesnika u svim liječenim skupinama bili su bijelci (90%).
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology and genotoxicity.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije i genotoksičnosti.
English: In a 26-week transgenic mouse model for carcinogenicity, no evidence of carcinogenicity was found.
Croatian: U transgeničnom modelu miša za ispitivanje karcinogenosti nakon 26 tjedana nije pronađen dokaz karcinogenosti.
English: A risk to the breastfed new-borns/infants cannot be excluded.
Croatian: Ne može se isključiti rizik za dojenu novorođenčad/dojenčad.
English: It is unknown whether ataluren/metabolites are excreted in human milk.
Croatian: Nije poznato izlučuju li se ataluren/metaboliti u ljudsko mlijeko.
English: In the event of a suspected overdose, supportive medical care should be provided including consulting with a healthcare professional and close observation of the clinical status of the patient.
Croatian: U slučaju sumnje na predoziranje, potrebno je pružiti dodatnu liječničku skrb, uključujući i konzultiranje sa zdravstvenim djelatnicima i pažljivo praćenje kliničkog statusa bolesnika.
English: Your doctor will test the levels of lipids (fats such as cholesterol and triglycerides) in your blood and your kidney function every 6 to 12 months.
Croatian: Vaš će liječnik provjeriti razinu lipida (masti poput kolesterola i triglicerida) u krvi i funkciju Vaših bubrega svakih 6 do 12 mjeseci.
English: Due to the low number of other races included in the clinical studies, no conclusions can be drawn on the effect of UGT1A9 in other ethnic groups.
Croatian: Uslijed malog broja drugih rasa uključenih u klinička ispitivanja, ne mogu se donijeti zaključci o utjecaju UGT1A9 u drugim etničkim grupama.
English: Name and address of the manufacturer responsible for batch release Almac Pharma Services Ltd.
Croatian: Naziv i adresa proizvođača odgovornog za puštanje serije lijeka u promet Almac Pharma Services Ltd.
English: No effects on male and female fertility were observed, but effects of early juvenile treatment on fertility during adulthood were not investigated.
Croatian: Nisu uočeni učinci na mušku i žensku plodnost, no nije istražen učinak liječenja u ranoj mladosti na plodnost tijekom odrasle dobi.
English: However there were no apparent effects of gender on ataluren plasma exposure in other populations.
Croatian: No, nema očitog utjecaja spola na izloženost atalurenu u plazmi u drugim populacijama.
English: The onset of reduction in relative bioavailability is estimated to occur approximately 60 hours after the first dose.
Croatian: Nastup smanjivanja u relativnoj bioraspoloživosti procijenjen je na otprilike 60 sati nakon prve doze.
English: Almac Pharma Services 22 Seagoe Industrial Estate Craigavon BT63 5QD United Kingdom
Croatian: AlmacPharma Services 22 Seagoe Industrial Estate Craigavon BT63 5QD Ujedinjeno Kraljevstvo
English: Background incidence of this tumour type in rats as well as humans is very low and the mechanism causing these tumours in the rat studies (including its relation to ataluren treatment) is unknown.
Croatian: Osnovna incidencija ovog tipa tumora u štakora kao i u ljudi vrlo je niska, a mehanizam koji uzrokuje ovaj tumor u ispitivanjima u štakora (uključujući njegov odnos s liječenjem atalurenom) nije poznat.
English: For example, you might take Translarna at 7:00 AM in the morning with breakfast, at 1:00 PM in the afternoon with lunch, and again at around 7:00 PM in the evening with dinner.
Croatian: Primjerice, lijek Translarna možete uzeti u 7:00 ujutro zajedno s doručkom, u 13:00 sati popodne zajedno s ručkom, te ponovno oko 19:00 sati uvečer s večerom.
English: It is important to take the correct dose.
Croatian: Primjena ispravne doze je važna.
English: In addition to the above mentioned effects, several other less adverse effects were found in the repeat dose studies; in particular decreased body weight gain, food intake and increased liver weight without a histological correlate and of unclear clinical significance.
Croatian: Uz prethodno spomenute učinke, utvrđeno je nekoliko drugih manje štetnih učinaka u ispitivanjima ponovljene doze; posebice smanjeno povećanje tjelesne težine, smanjen unos hrane i povećana masa jetre bez histološkog korelata i nejasnog kliničkog značaja.
English: The significance of these findings for humans is unknown.
Croatian: Značaj ovih nalaza za ljude nije poznat.
English: The amount of the liquid or semi-solid food can be increased based on patient preference.
Croatian: Količina tekućine ili polukrute hrane može se povećati na temelju preferencije bolesnika.