FrancophonIA/ELRC3.0 huggingface dataset:
English: In patients with mild to moderate hepatic impairment, treatment with TRITAZIDE must be initiated only under close medical supervision and the maximum daily doses are 2.5 mg of ramipril and 12.5 mg of hydrochlorothiazide.
Slovenian: Bolnikom z blago do zmerno okvaro jeter je treba zdravljenje s TRITAZIDE uvesti pod natančnim zdravniškim nadzorom; največji dnevni odmerek za takšne bolnike je 2,5 mg ramiprila in 12,5 mg hidroklorotiazida.
English: Estonia:
Slovenian: Estonija:
English: • Medicines used for the treatment of low blood pressure, shock, cardiac failure, asthma or allergies such as ephedrine, noradrenaline or adrenaline.
Slovenian: • zdravila za zdravljenje nizkega krvnega tlaka, šoka, srčnega popuščanja, astme ali alergij, npr.
English: • Increased or irregular heartbeat
Slovenian: • hitrejše ali neredno bitje srca
English: Sensitivity reactions may occur in patients with or without a history of allergy or bronchial asthma.
Slovenian: Preobčutljivostne reakcije se lahko pojavijo tako pri bolnikih z anamnezo alergije ali bronhialne astme kot pri bolnikih brez takšne anamneze.
English: Hepatic Encephalopathy
Slovenian: Hepatična encefalopatija
English: Symptoms associated with overdosage of ACE inhibitors may include excessive peripheral vasodilatation (with marked hypotension, shock), bradycardia, electrolyte disturbances, renal failure, cardiac arrhythmia, impairment of consciousness including coma, cerebral convulsions, pareses, and paralytic ileus.
Slovenian: Med simptomi prevelikega odmerjanja zaviralcev ACE so lahko čezmerna periferna vazodilatacija (z izrazito hipotenzijo, šokom), bradikardija, elektrolitske motnje, odpoved ledvic, motnje srčnega ritma, okvare zavesti, vključno s komo, cerebralne konvulzije, pareze in paralitični ileus.
English: Infants whose mothers have taken ACE inhibitors should be closely observed for hypotension (see also section 4.3 and 4.4)”.
Slovenian: Pri dojenčkih, katerih matere so jemale zaviralce ACE, je treba skrbno spremljati morebitni pojav hipotenzije (glejte tudi poglavji 4.3 in 4.4)“.
English: Myocardial ischaemia including angina pectoris, tachycardia, arrhythmia, palpitations, oedema peripheral
Slovenian: Srčne bolezni ishemija miokarda, vključno z angino pektoris, tahikardija, aritmija, palpitacije, periferni edemi miokardni infarkt
English: The blood-pressure-lowering effect is accompanied by slight increases in the filtration fraction, renal vascular resistance and plasma renin activity.
Slovenian: Učinek na znižanje krvnega tlaka spremlja rahlo povečanje filtracijske frakcije, ledvične žilne upornosti in aktivnosti renina v plazmi.
English: • If you have kidney problems where the blood supply to your kidney is reduced(renal artery stenosis)
Slovenian: • če imate težave z ledvicami, pri katerih je prekrvitev ledvic zmanjšana (zožitev ledvične arterije).
English: Ramipril belongs to a group of medicines called “ACE inhibitors” (Angiotensin Converting Enzyme Inhibitors).
Slovenian: Ramipril spada v skupino zdravil, ki jih imenujemo zaviralci ACE (zaviralci angiotenzinske konvertaze).
English: It works by:
Slovenian: Deluje tako, da:
English: The combination of ramipril and hydrochlorothiazide with lithium is therefore not recommended.
Slovenian: Kombinacija ramiprila in hidroklorotiazida z litijem zato ni priporočljiva.
English: Ramiprilat, the active metabolite of ramipril is poorly removed from the general circulation by haemodialysis.
Slovenian: Ramiprilat, aktivni presnovek ramiprila, se s hemodializo slabo odstrani iz splošnega obtoka.
English: Considering a paucity of trial data assessing titration steps with the combination the posology has been amended.
Slovenian: Zaradi nezadostne količine podatkov iz preiskav o korakih pri titraciji s kombinacijo je dopolnjeno poglavje o odmerjanju.
English: Dilutional hyponatraemia may occur.
Slovenian: Pojavi se lahko dilucijska hiponatriemija.
English: • Severe flaking or peeling of the skin, itchy, lumpy rash or other skin reactions such as red rash on your face or forehead
Slovenian: • hudo luščenje ali lupljenje kože, srbeč in bulast izpuščaj ali druge reakcije na koži, npr. rdeč izpuščaj na obrazu ali čelu
English: Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation.
Slovenian: Zmanjšano nastajanje angiotenzina II in zavrtje razgradnje bradikinina povzročita vazodilatacijo.
English: - History of hereditary or idiopathic angioedema - Extracorporeal treatments leading to contact of blood with negatively charged surfaces (see section 4.5) - Significant bilateral renal artery stenosis or renal artery stenosis in a single functioning kidney - -2nd and 3rd trimester of pregnancy (see section 4.4 and 4.6) - Lactation (see section 4.6) - Severe impairment of renal function with a creatinine clearance below 30 ml/min in undialysed patients - Clinically relevant electrolyte disturbances which may worsen following treatment with TRITAZIDE (see section 4.4) - Severe impairment of liver function, hepatic encephalopathy
Slovenian: - Anamneza dednega ali idiopatskega angioedema - Zunajtelesno zdravljenje, pri katerem gre za stik krvi z negativno nabitimi površinami (glejte poglavje 4.5) - Močna obojestranska stenoza ledvične arterije ali stenoza ledvične arterije pri samo eni delujoči ledvici - Drugo in tretje trimesečje nosečnosti (glejte poglavji 4.4 in 4.6) - Dojenje (glejte poglavje 4.6) - Močno okrnjeno delovanje ledvic z očistkom kreatinina pod 30 ml/min pri bolnikih, ki niso na dializi - Klinično pomembne elektrolitske motnje, ki lahko negativno vplivajo na prihodnje zdravljenje z zdravilom TRITAZIDE (glejte poglavje 4.4) - Močna okrnitev delovanja jeter, jetrna encefalopatija
English: In diabetic patients dosage adjustments of insulin or oral hypoglycaemic agents may be required.
Slovenian: Pri sladkornih bolnikih utegne biti potrebna prilagoditev odmerkov insulina ali peroralnih antidiabetikov.
English: This results in elevated plasma concentrations of hydrochlorothiazide, which decrease more slowly than in subjects with normal renal function.
Slovenian: Posledica je večja koncentracija hidroklorotiazid v plazmi, ki se zmanjšuje počasneje kot pri osebah z normalnim delovanjem ledvic.
English: Hypersensitivity to sulphonamide-derived active substances, hypokalaemia and nuclear icterus might occur.
Slovenian: Pojavijo se lahko preobčutljivost na zdravilne učinkovine, izpeljane iz sulfonamidov, hipokaliemija in jedrni ikterus.
English: • If you are breast-feeding (see section below on “Pregnancy and breast-feeding”).
Slovenian: • če dojite (glejte spodaj, poglavje "Nosečnost in dojenje").
English: If ramipril + hydrochlorothiazide is used in a patient with primary hyperaldosteronism, then careful monitoring of plasma potassium level is required.
Slovenian: Če je kombinacija ramiprila in hidroklorotiazida uporabljena pri bolniku s primarnim hiperaldosteronizmom, je treba natančno kontrolirati koncentracijo kalija v plazmi.
English: When pregnancy is diagnosed, treatment with ACE inhibitors/ AIIRAs should be stopped immediately, and, if appropriate, alternative therapy should be started (see sections 4.3 and 4.6).
Slovenian: Zdravljenje z zaviralci ACE/AIIRA je treba prekiniti takoj po ugotovitvi nosečnosti in uvesti drugo zdravljenje, če je primerno (glejte poglavji 4.3 in 4.6).
English: Digitalis preparations, active substances known to prolong the QT interval and antiarrhythmics: their proarrhythmic toxicity may be increased or their antiarrhythmic effect decreased in the presence of electrolyte disturbances (e.g. hypokalaemia, hypomagnesaemia).
Slovenian: Pripravki digitalisa, zdravilne učinkovine, ki podaljšujejo interval QT, in antiaritmiki: Proaritmični toksični učinki se lahko v primeru elektrolitskih motenj (npr. hipokaliemije, hipomagneziemije) povečajo ali se zmanjša njihov antiaritmični učinek.
English: • More sugar than usual in your water (urine)
Slovenian: • več sladkorja v urinu, kot po navadi
English: The CHMP also adopted a harmonised wording regarding pregnancy and lactation under this section (see SPC).
Slovenian: CHMP je v to poglavje vključil tudi usklajeno besedilo o nosečnosti in dojenju (glejte povzetek glavnih značilnosti zdravila).
English: The peak effect of a single dose is usually reached 3 to 6 hours after oral administration.
Slovenian: Največji učinek posamičnega odmerka je po navadi dosežen v 3 do 6 urah po peroralni uporabi.
English: • Skin rash with or without raised area
Slovenian: • izpuščaj na koži, z dvignjenim predelom ali brez njega
English: • If you are allergic (hypersensitive) to ramipril, hydrochlorothiazide or any of the other ingredients of TRITAZIDE (see section 6)
Slovenian: • če ste alergični (preobčutljivi) na ramipril, hidroklorotiazid ali katerokoli sestavino zdravila TRITAZIDE (glejte poglavje 6).
English: ACE inhibitor-induced cough should be considered as part of the differential diagnosis of cough”
Slovenian: Kašelj, ki nastane zaradi uporabe zaviralcev ACE, je treba obravnavati kot del diferencialne diagnoze kašlja.“
English: Peak plasma concentrations of ramiprilat, the sole active metabolite of ramipril are reached 2-4 hours after ramipril intake.
Slovenian: Največja koncentracija ramiprilata, edinega aktivnega presnovka ramiprila, v plazmi je dosežena od 2 do 4 ure po zaužitju ramiprila.
English: In patients with impaired liver function, the metabolism of ramipril to ramiprilat was delayed due to diminished activity of hepatic esterases, and plasma ramipril levels in these patients were increased.
Slovenian: Pri bolnikih z okvarjenim delovanjem jeter je presnova ramiprila v ramiprilat upočasnjena zaradi manjše aktivnosti jetrnih esteraz in koncentracija ramiprila v plazmi teh bolnikov je povečana.
English: These could be signs of lung problems including inflammation
Slovenian: To so lahko znaki težav s pljuči, vključno z vnetjem.
English: Latent diabetes mellitus may become manifest during thiazide therapy.
Slovenian: Prikrita sladkorna bolezen lahko postane med zdravljenjem s tiazidi očitna.
English: ACE inhibitors cause higher rate of angioedema in black patients than in non black patients.
Slovenian: Zaviralci ACE angioedem pogosteje povzročijo pri bolnikih-črncih kot nečrncih.
English: • Red, itchy, swollen or watery eyes
Slovenian: • rdeče, srbeče, otekle ali solzeče se oči
English: Patients at risk for development of hyperkalaemia include those with renal insufficiency, age (> 70 years), uncontrolled diabetes mellitus, or those using potassium salts, potassium retaining diuretics and other plasma potassium increasing active substances or conditions such as dehydration, acute cardiac decompensation, metabolic acidosis.
Slovenian: Med bolniki, ki jih ogroža hiperkaliemija, so tisti z insuficienco ledvic, starejši bolniki (> 70 let), bolniki z neurejeno sladkorno boleznijo, uporabniki kalijevih soli, diuretikov, ki ohranjajo kalij, in drugih zdravil, ki zvišujejo kalij v plazmi, in bolniki z motnjami, kakršne so npr. dehidracija, akutno srčno popuščanje, metabolična acidoza.
English: The concurrent administration of ramipril and hydrochlorothiazide does not affect their bioavailability.
Slovenian: Sočasna uporaba ramiprila in hidroklorotiazida ne vpliva na njuno biološko uporabnost.
English: • If you are having a test for parathyroid function.
Slovenian: • če imate preiskavo delovanja obščitničnih žlez.
English: TRITAZIDE is contraindicated in severe hepatic impairment (see section 4.3).
Slovenian: TRITAZIDE je kontraindiciran v primeru hude okvare jeter (glejte poglavje 4.3).
English: Quinine : hydrochlorothiazide reduces quinine excretion.
Slovenian: Kinin : Hidroklorotiazid zmanjša izločanje kinina.
English: In patients concurrently treated with diuretics, as hypotension may occur following initiation of the treatment, caution is recommended.
Slovenian: Bolnikom, ki sočasno dobivajo diuretike, se lahko po uvedbi tega zdravila pojavi hipotenzija, zato je potrebna previdnost.
English: DATE OF REVISION OF THE TEXT [To be completed nationally]
Slovenian: 10 DATUM ZADNJE REVIZIJE BESEDILA [Izpolni država članica]
English: Taking TRITAZIDE with other medicines
Slovenian: Jemanje z drugimi zdravili
English: If necessary, the dose can be progressively increased to achieve target blood pressure; the maximum permitted doses are 10 mg of ramipril and 25 mg of hydrochlorothiazide daily”
Slovenian: Po potrebi je odmerek mogoče postopoma povečevati, tako da se doseže želen krvni tlak; največji dovoljeni odmerek ramiprila je 10 mg, hidroklorotiazida pa 25 mg dnevno.“
English: • Drinking alcohol with TRITAZIDE may make you feel dizzy or light-headed.
Slovenian: • Pitje alkoholnih pijač hkrati z jemanjem zdravila TRITAZIDE lahko povzroči omotico ali vrtoglavost.
English: HOW TO TAKE TRITAZIDE
Slovenian: KAKO JEMATI ZDRAVILO TRITAZIDE
English: Thiazide therapy may impair glucose tolerance.
Slovenian: Zdravljenje s tiazidi lahko poslabša toleranco za glukozo.
English: • Bruising more easily, bleeding for longer than normal, any sign of bleeding (e.g. bleeding from the gums), purple spots, blotching on the skin or getting infections more easily than usual, sore throat and fever, feeling tired, faint, dizzy or having pale skin.
Slovenian: • večja nagnjenost k podplutbam, dolgotrajnejše krvavitve kot po navadi, kakršnekoli krvavitve (npr. krvavitev iz dlesni), vijoličaste pege na koži ali večja nagnjenost k okužbam kot po navadi, vnetje žrela in zvišana telesna temperatura, utrujenost, omedlevica, omotica ali bledica.
English: You must tell your doctor if you think that you are (or might become) pregnant You should not take TRITAZIDE in the first 12 weeks of pregnancy, and you must not take them at all after the 13th week as their use during pregnancy may possibly be harmful to the baby.
Slovenian: Zdravila TRITAZIDE ni dobro jemati v prvih 12 tednih nosečnosti, od 13. tedna naprej pa ga sploh ne smete jemati, ker lahko njegova uporaba med nosečnostjo škoduje otroku.
English: Portugal:
Slovenian: Portugalska:
English: Lithium salts: Excretion of lithium may be reduced by ACE inhibitors and therefore lithium toxicity may be increased.
Slovenian: Soli litija: Zaviralci ACE lahko zmanjšajo izločanje litija, zato se lahko toksični učinki litija povečajo.
English: Common (affects less than 1 in 10 people)
Slovenian: Pogosti (pojavijo se pri manj kot 1 od 10 bolnikov)
English: If necessary, the dose can be progressively increased to achieve target blood pressure; the maximum permitted doses are 10 mg of ramipril and 25 mg of hydrochlorothiazide daily.
Slovenian: Če je treba, je mogoče odmerek postopoma povečevati, da se doseže ciljni krvni tlak; največji dovoljeni odmerek je 10 mg ramiprila in 25 hidroklorotiazida na dan.
English: • Procainamide (for heart rhythm problems)
Slovenian: • prokainamid (proti motnjam srčnega ritma).
English: Neutropenia/agranulocytosis have been rarely seen and bone marrow depression has also been reported.
Slovenian: Redko so zabeležili nevtropenijo/agranulocitozo, opisana je bila tudi depresija kostnega mozga.
English: Renal excretion of hydrochlorothiazide is reduced in patients with impaired renal function, and renal hydrochlorothiazide clearance is proportionally related to creatinine clearance.
Slovenian: Ledvično izločanje hidroklorotiazida je zmanjšano pri bolnikih z okvarjenim delovanjem ledvic in ledvični očistek hidroklorotiazida je sorazmeren očistku kreatinina.
English: The two active substances have inverse effects on plasma potassium.
Slovenian: Zdravilni učinkovini imata nasprotujoč si učinek na kalij v plazmi.
English: After multiple once-daily doses of ramipril, the effective half-life of ramiprilat concentrations was 1317 hours for the 5-10 mg doses and longer for the lower 1.25-2.5 mg doses.
Slovenian: Efektivni razpolovni čas koncentracije ramiprilata po večkratni uporabi ramiprila enkrat na dan je pri odmerkih od 5 do 10 mg ramiprila od 13 do 17 ur, pri manjših odmerkih (od 1,25 do 2,5 mg) pa je daljši.
English: SPECIAL STORAGE CONDITIONS [To be completed nationally]
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE [Izpolni država članica]
English: Hydrochlorothiazide can reduce plasma volume as well as the uteroplacental blood flow.
Slovenian: Hidroklorotiazid lahko zmanjša volumen plazme in krvni pretok skozi maternico in placento.
English: Furthermore, concomitant treatment of ACE inhibitors and NSAIDs may lead to an increased risk of worsening of renal function and to an increase in kalaemia.
Slovenian: Poleg tega lahko sočasno zdravljenje z zaviralci ACE in nesteroidnimi protivnetnimi zdravili poveča tveganje poslabšanja delovanja ledvic in zvišanje kalija v krvi.
English: 4.2 Posology and Method of Administration
Slovenian: 4.2 Odmerjanje in način uporabe
English: In predisposed patients (e.g. prostatic hyperplasia) hydrochlorothiazide overdose may induce acute urinary retention.
Slovenian: Pri predisponiranih bolnikih (npr. tistih s hiperplazijo prostate) lahko preveliko odmerjanje hidroklorotiazida izzove akuten zastoj urina.
English: • Patients with liver disease
Slovenian: • Bolniki z boleznijo jeter
English: ACE inhibitor/ Angiotensin II Receptor Antagonist (AIIRA) therapy exposure during the second and third trimesters is known to induce human fetotoxicity (decreased renal function, oligohydramnios, skull ossification retardation) and neonatal toxicity (renal failure, hypotension, hyperkalaemia).
Slovenian: Izpostavljenost zdravilom z zaviralcem ACE/antagonistom receptorjev angiotenzina II (AIIRA) v drugem in tretjem trimesečju dokazano povzroča humano fetotoksičnost (okrnjeno delovanje ledvic, oligohidramnij, zakasnjena okostenitev lobanje) in neonatalno toksičnost (odpoved ledvic, hipotenzija,
English: Electrolyte disturbances due to diuretic therapy including hydrochlorothiazide may cause hepatic encephalopathy in patients with liver disease.
Slovenian: Pri bolnikih z boleznijo jeter lahko elektrolitske motnje zaradi zdravljenja z diuretiki, vključno s hidroklorotiazidom, povzročijo hepatično encefalopatijo.
English: - the scope of the referral was the harmonisation of the Summaries of Products Characteristics, labelling and package leaflet.
Slovenian: - je bil namen napotitve uskladitev povzetkov glavnih značilnosti zdravila, označevanja in navodila za uporabo,
English: • Do not crush or chew the tablets.
Slovenian: • Tablet ne smete zdrobiti ali zgristi.
English: This results in elevated plasma concentrations of ramiprilat, which decrease more slowly than in subjects with normal renal function.
Slovenian: Posledica je večja koncentracija ramiprilata v plazmi, ki se zmanjšuje počasneje kot pri osebah z normalnim delovanjem ledvic.
English: Alveolitis allergic, non cardiogenic pulmonary oedema due to hydrochlorothiazide
Slovenian: alergijski alveolitis, nekardiogeni pljučni edem zaradi hidroklorotiazida
English: Other side effects reported:
Slovenian: Drugi opisani neželeni učinki so:
English: Based on urinary recovery, the extent of absorption is at least 56 % and is not significantly influenced by the presence of food in the gastrointestinal tract.
Slovenian: Na podlagi pojavljanja v urinu je delež absorpcije vsaj 56 %.
English: If you have any questions or are not sure about anything, ask your doctor or pharmacist.
Slovenian: Če imate dodatna vprašanja ali ste glede česa negotovi, se posvetujte z zdravnikom ali s farmacevtom.
English: (urticaria), red marks on the hands, feet and throat, swelling of the throat and tongue, swelling around the eyes and lips, difficulty breathing and swallowing
Slovenian: Med njenimi znaki so srbenje, koprivnica (urtikarija), rdeče spremembe na rokah, stopalih in žrelu, oteklost žrela in jezika, oteklost okrog oči in ustnic, težko dihanje in težko požiranje.
English: MARKETING AUTHORISATION NUMBER(S) [To be completed nationally]
Slovenian: ŠTEVILKA(E) DOVOLJENJA(DOVOLJENJ) ZA PROMET) [Izpolni država članica]
English: Hydrochlorothiazide is a thiazide diuretic.
Slovenian: Hidroklorotiazid je tiaziden diuretik.
English: You should not take TRITAZIDE if you are breast-feeding.
Slovenian: Zdravila TRITAZIDE ne smete jemati, če dojite.
English: Italy:
Slovenian: Italija:
English: Plasma concentrations of ramiprilat decline in a polyphasic manner.
Slovenian: Koncentracija ramiprilata v plazmi se zmanjšuje v več fazah.
English: Treatment should be immediately discontinued in case of hepatic encephalopathy.
Slovenian: V primeru hepatične encefalopatije je treba zdravljenje takoj prekiniti.
English: Tests
Slovenian: Preiskave
English: TRITAZIDE may lower your blood sugar amounts.
Slovenian: Zdravilo TRITAZIDE lahko zniža krvni sladkor.
English: Uncommon ( affects less than 1 in 100 people)
Slovenian: Občasni (pojavijo se pri manj kot 1 od 100 bolnikov)
English: Following oral administration ramipril is rapidly absorbed from the gastrointestinal tract; peak plasma concentrations of ramipril are reached within one hour.
Slovenian: Po peroralni uporabi se ramipril hitro absorbira iz prebavil: največjo koncentracijo v plazmi doseže v eni uri.
English: Should exposure to ACE inhibitor have occurred from the second trimester of pregnancy, ultrasound check of renal function and skull is recommended.
Slovenian: Če je bila oseba izpostavljena zaviralcu ACE v drugem trimesečju nosečnosti, je priporočljivo izvesti pregled delovanja ledvic in lobanje z ultrazvokom.
English: In most patients the onset of the antihypertensive effect of a single dose becomes apparent 1 to 2 hours after oral administration.
Slovenian: Antihipertenzivni učinek posamičnega odmerka se pri večini bolnikov pojavi približno 1 do 2 uri po peroralni uporabi.
English: Consideration must be given to reducing the diuretic dose or discontinuing the diuretic before starting treatment with TRITAZIDE.
Slovenian: Pred začetkom zdravljenja s TRITAZIDE je treba razmisliti o zmanjšanju odmerka diuretika ali prenehanju njegove uporabe.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION [To be completed nationally]
Slovenian: 9 DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET [Izpolni država članica]
English: • Constipation, stomach or gut pain
Slovenian: • zaprtje, bolečine v želodcu ali trebuhu
English: • Blocked nose, inflammation of your sinuses (sinusitis), shortness of breath
Slovenian: • zamašenost nosu, vnetje obnosnih votlin (sinuzitis), kratka sapa
English: A single oral dose of ramipril produced an undetectable level of ramipril and its metabolites in breast milk.
Slovenian: Posamičen peroralen odmerek ramiprila je povzročil nemerljivo koncentracija ramiprila in njegovih presnovkov v materinem mleku.
English: There were however some contraindications with HCTZ labelled in some local SPC's and not proposed in the harmonised SPC.
Slovenian: Nekatere kontraindikacije HCTZ so navedene v nekaterih lokalnih povzetkih glavnih značilnosti zdravila in niso predlagane v usklajenem povzetku glavnih značilnosti zdravila.
English: ANNEX III SUMMARY OF PRODUCT CHARACTERISTICS, LABELLING AND PACKAGE LEAFLET
Slovenian: DODATEK III POVZETEK GLAVNIH ZNAČILNOSTI ZDRAVILA, OZNAČEVANJE IN NAVODILO ZA UPORABO
English: • A swelling in your gut called “intestinal angioedema” presenting with symptoms like abdominal pain,
Slovenian: • oteklost črevesa, ki jo imenujemo "intestinalni angioedem" in se kaže s simptomi, kot so bolečine v trebuhu, bruhanje in driska
English: D-65926 Frankfurt am Main, Germany
Slovenian: D-65926 Frankfurt am Main, Nemčija
English: Germany:
Slovenian: Nemčija:
English: Ramipril/Hydrochlorothiazide
Slovenian: ramipril/hidroklorotiazid
English: Unless continued ACE inhibitor/ AIIRAs therapy is considered essential, patients planning pregnancy should be changed to alternative anti-hypertensive treatments which have an established safety profile for use in pregnancy.
Slovenian: Če nadaljnje zdravljenje z zaviralci ACE/AIIRA ni nujno, je treba bolnice, ki načrtujejo nosečnost, prevesti na druga antihipertenzivna zdravila, katerih varnostne značilnosti med nosečnostjo so ugotovljene.
English: The ramipril active substance may induce persistent dry cough, while the hydrochlorothiazide active substance may lead to worsening of glucose, lipid and uric acid metabolism.
Slovenian: Zdravilna učinkovina ramipril lahko povzroči trdovraten suh kašelj, zdravilna učinkovina hidroklorotiazid pa poslabšanje presnove glukoze, lipidov in sečne kisline.