FrancophonIA/ELRC3.0 huggingface dataset:
English: The safety profile was similar when comparing patients receiving intravenous tedizolid phosphate alone to patients who received oral administration alone, except for a higher reported rate of gastrointestinal disorders associated with oral administration.
Croatian: Sigurnosni profil bio je sličan kada se usporede bolesnici koji su primali samo intravenski tedizolidfosfat s bolesnicima koji su primali lijek samo peroralno, osim za višu prijavljenu stopu poremećaja probavnog sustava povezanih s peroralnom primjenom.
English: Haemodialysis does not result in meaningful removal of tedizolid from systemic circulation, as assessed in subjects with end-stage renal disease (eGFR <15 mL/min).
Croatian: Hemodijaliza ne rezultira značajnim uklanjanjem tedizolida iz sistemske cirkulacije, kao što je procijenjeno u ispitanika u završnom stadiju bubrežne bolesti (eGFR <15 ml/min).
English: The reconstituted solution should be inspected visually for particulate matter prior to administration.
Croatian: Rekonstituiranu otopinu treba prije primjene vizualno pregledati na postojanje čestica.
English: • Abscess (swollen, pus-filled lump)
Croatian: • apsces (otečena, gnojna kvržica)
English: • Vaginal infection, inflammation or itching
Croatian: • vaginalna infekcija, upala ili svrbež
English: Insomnia Sleep disorder Anxiety Nightmare
Croatian: Psihijatrijski poremećaji nesanica poremećaji spavanja anksioznost noćne more
English: If you forget to take Sivextro
Croatian: Ako ste zaboravili uzeti Sivextro
English: • Decrease or loss of skin sensitivity, tingling/prickling skin sensation
Croatian: • smanjena osjetljivost kože ili gubitak osjetljivosti kože, trnci/osjećaj peckanja na koži
English: Sivextro must be reconstituted with water for injections and subsequently diluted in 250 mL of 0.9% sodium chloride for infusion.
Croatian: Sivextro se mora rekonstituirati s vodom za injekcije i zatim razrijediti u 250 ml 0,9%-tne otopine natrijevog klorida za infuziju.
English: Decreased platelets, decreased haemoglobin and decreased neutrophils have been observed in a few subjects during treatment with tedizolid phosphate.
Croatian: Smanjen broj trombocita, smanjena razina hemoglobina i smanjen broj neutrofila primijećeni su u nekoliko ispitanika tijekom liječenja tedizolidfosfatom.
English: What Sivextro looks like and contents of the pack Sivextro is an oval, yellow film-coated tablet imprinted with ‘TZD' on one side and ‘200' on the other side.
Croatian: Sivextro je ovalna, žuta filmom obložena tableta s utisnutom oznakom „TZD“ na jednoj strani i „200“ na drugoj strani.
English: In a 1-month immunotoxicology study in rats, repeated oral dosing of tedizolid phosphate was shown to significantly reduce splenic B cells and T cells and reduce plasma IgG titers.
Croatian: U jednomjesečnom ispitivanju imunotoksičnosti u štakora, ponovljeno peroralno doziranje tedizolidfosfata značajno je smanjilo B stanice i T stanice slezene i smanjilo je IgG titar u plazmi.
English: Mitochondrial dysfunction
Croatian: Poremećaj funkcije mitohondrija
English: Tedizolid did not alter activity of selected CYP isoenzymes, but induction of CYP3A4 mRNA was observed in vitro in hepatocytes.
Croatian: Tedizolid nije promijenio aktivnost tih izoenzima CYP, ali je zabilježena indukcija CYP3A4 mRNA in vitro u hepatocitima.
English: • Swelling in ankles and/or feet
Croatian: • oticanje gležnjeva i/ili stopala
English: There are no data from the use of tedizolid phosphate in pregnant women.
Croatian: Nema podataka o primjeni tedizolidfosfata u trudnica.
English: At steady state, tedizolid mean (SD) Cmax values of 2.2 (0.6) and 3.0 (0.7) mcg/mL and AUC values of 25.6 (8.5) and 29.2 (6.2) mcg·h/mL were similar with oral and IV administration of tedizolid phosphate, respectively.
Croatian: U stanju dinamičke ravnoteže, srednje vrijednosti (SD) Cmax od 2,2 (0,6) i 3,0 (0,7) μg/ml i vrijednosti AUC od 25,6 (8,5) i 29,2 (6,2) μg·h/ml tedizolida bile su slične kod peroralne, odnosno intravenske primjene tedizolidfosfata.
English: Do not take any medicine to treat your diarrhoea without first checking with your doctor.
Croatian: Nemojte uzimati lijekove protiv proljeva prije nego što se posavjetujete sa svojim liječnikom.
English: , Mg including Lactated Ringer's Injection and Hartmann's Solution.
Croatian: ), uključujući otopinu za injekciju Ringerovog laktata i Hartmannovu otopinu.
English: No dose adjustment is necessary for co-administered CYP3A4 substrates during treatment with Sivextro.
Croatian: Nije potrebna prilagodba doze istodobno primijenjenih supstrata CYP3A4 tijekom liječenja lijekom Sivextro.
English: If in any doubt, contact your pharmacist for advice.
Croatian: Ako niste sigurni, obratite se ljekarniku za savjet.
English: Two placebo-controlled crossover studies were conducted to assess the potential of 200 mg oral tedizolid phosphate at steady state to enhance pressor responses to pseudoephedrine and tyramine in healthy individuals.
Croatian: Provedena su dva placebom kontrolirana ukrižena ispitivanja kako bi se procijenio potencijal 200 mg peroralnog tedizolidfosfata u stanju dinamičke ravnoteže za povećanje presorskog odgovora na pseudoefedrin i tiramin u zdravih osoba.
English: Following administration of a single 200 mg oral dose of tedizolid phosphate, the pharmacokinetics of tedizolid are not altered in patients with moderate (n=8) or severe (n=8) hepatic impairment (Child-Pugh Class B and C).
Croatian: Nakon primjene jednokratne peroralne doze tedizolidfosfata od 200 mg, farmakokinetika tedizolida nije se promijenila u bolesnika s umjerenim (n=8) ili teškim (n=8) oštećenjem funkcije jetre (Child-Pugh stadij B i C).
English: • loss of sensitivity in your hands or feet (such as numbness, prickling/tingling, or sharp pains)
Croatian: • gubitak osjetljivosti u šakama ili stopalima (primjerice utrnulost, peckanje/trnci ili oštri bolovi)
English: Table 1 Frequency of adverse reactions by System Organ Class in comparative clinical studies
Croatian: Tablica 1 Učestalost nuspojava prema klasifikaciji organskih sustava u usporednim kliničkim ispitivanjima
English: Neuropathy (optic and peripheral) has not been reported in patients treated with tedizolid phosphate at the recommended treatment duration of 6 days.
Croatian: Neuropatija (optička i periferna) nije zabilježena u bolesnika liječenih tedizolidfosfatom tijekom preporučenog trajanja liječenja od 6 dana.
English: Tedizolid phosphate is converted by endogenous plasma and tissue phosphatases to the microbiologically active moiety, tedizolid.
Croatian: Tedizolidfosfat se pretvara endogenim fosfatazama plazme i tkiva u mikrobiološki aktivni spoj, tedizolid.
English: Reconstitute the contents of the vial with 4 mL water for injections, and swirl gently until the powder has dissolved entirely.
Croatian: Rekonstituirajte sadržaj bočice sa 4 ml vode za injekcije i lagano okrećite dok se prašak potpuno ne otopi.
English: • Respiratory tract (sinuses, throat and chest) infection
Croatian: • infekcija dišnih puteva (sinusi, grlo i prsište)
English: There is no Phase 3 clinical experience in patients with co-administration of tedizolid phosphate with serotonergic agents such as selective serotonin re-uptake inhibitors [SSRI], serotonin norepinephrine reuptake inhibitors (SNRI), tricyclic antidepressants, MAO inhibitors, triptans, and other medicines with potential adrenergic or serotonergic activity.
Croatian: Nema iskustva iz kliničkih ispitivanja faze 3 u bolesnika s istodobnom primjenom tedizolidfosfata uz serotonergičke lijekove kao što su selektivni inhibitori ponovne pohrane serotonina [engl. selective serotonin re-uptake inhibitors, SSRI], inhibitori ponovne pohrane serotonina i noradrenalina (engl. serotonin norepinephrine reuptake inhibitors, SNRI), triciklički antidepresivi, inhibitori MAO, triptani i drugi lijekovi s potencijalnom adrenergičkom ili serotonergičkom aktivnošću.
English: In a mouse thigh infection model of S. aureus, the antibacterial activity of tedizolid was reduced in the absence of granulocytes.
Croatian: U mišjem modelu infekcije bedra prouzročene bakterijom S. aureus, antibakterijska aktivnost tedizolida bila je smanjena u odsutnosti granulocita.
English: • sulfasalazine (used to treat inflammatory bowel diseases)
Croatian: • sulfasalazin (koristi se za liječenje upalnih bolesti crijeva)
English: If possible, an interruption of the coadministered BCRP substrate medicinal product (such as imatinib, lapatinib, methotrexate, pitavastatin, rosuvastatin, sulfasalazine, and topotecan) should be considered during the 6 days of treatment with oral tedizolid phosphate.
Croatian: Ako je moguće, potrebno je razmotriti prekid istodobne primjene lijeka koji je supstrat BCRP-a (kao što je imatinib, lapatinib, metotreksat, pitavastatin, rosuvastatin, sulfasalazin i topotekan) tijekom 6 dana liječenja peroralnom primjenom tedizolidfosfata.
English: Clostridioides difficile associated diarrhoea
Croatian: Proljev povezan s Clostridioides difficile
English: What Sivextro is and what it is used for What you need to know before you take Sivextro How to take Sivextro
Croatian: Što je Sivextro i za što se koristi Što morate znati prije nego počnete uzimati Sivextro Kako uzimati Sivextro
English: • if you are allergic to tedizolid phosphate or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte uzimati Sivextro: • ako ste alergični na tedizolidfosfat ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: The contents of the vial should be reconstituted with 4 mL of water for injections, and be swirled gently until the powder has dissolved entirely.
Croatian: Sadržaj bočice mora se rekonstituirati sa 4 ml vode za injekcije i lagano okretati dok se prašak potpuno ne otopi.
English: Sivextro is an antibiotic that contains the active substance tedizolid phosphate.
Croatian: Sivextro je antibiotik koji sadrži djelatnu tvar tedizolidfosfat.
English: Do not use this medicine after the expiry date which is stated on the vial label after “EXP”.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na bočici iza oznake „EXP“.
English: The safety and efficacy of tedizolid phosphate when administered for periods longer than 6 days have not been established.
Croatian: Sigurnost i djelotvornost tedizolidfosfata kada se primjenjuje duže od 6 dana nisu ustanovljene.
English: • Dry mouth, constipation, indigestion, pain/discomfort in the belly (abdomen), retching, dry heaving, bright red blood in the stool
Croatian: • suha usta, zatvor, probavne tegobe, bol/nelagoda u trbuhu (abdomenu), dizanje želuca, svijetlo crvena krv u stolici
English: Clostridioides difficile associated diarrhoea (CDAD) has been reported for tedizolid phosphate (see section 4.8).
Croatian: Clostridioides difficile associated diarrhoea, CDAD) (vidjeti dio 4.8).
English: • Sleepiness, abnormal sleep pattern, difficulty sleeping, nightmares (unpleasant/disturbing dreams)
Croatian: • pospanost, poremećen obrazac spavanja, poteškoće sa spavanjem, noćne more
English: Blood and lymphatic system disorders
Croatian: Poremećaji krvi i limfnog sustava limfadenopatija
English: In Phase 3 studies, subjects taking serotonergic agents including antidepressants such as selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and serotonin 5-hydroxytryptamine (5-HT1) receptor agonists (triptans), meperidine, or buspirone were excluded.
Croatian: U ispitivanjima faze 3 isključeni su ispitanici koji uzimaju serotonergičke lijekove uključujući antidepresive, primjerice selektivne inhibitore ponovne pohrane serotonina (engl. selective serotonin reuptake inhibitors, SSRI), tricikličke antidepresive i agoniste receptora serotonina 5-hidroksitriptamina (5-HT1) (triptane), meperidin ili buspiron.
English: • Swollen or enlarged lymph nodes
Croatian: • otečeni ili povećani limfni čvorovi
English: Following administration of a single 200 mg IV dose of tedizolid phosphate to 8 subjects with severe renal impairment defined as eGFR <30 mL/min, the Cmax was basically unchanged and AUC0-∞ was changed by less than 10% compared to 8 matched healthy subject controls.
Croatian: Nakon primjene jednokratne intravenske doze tedizolidfosfata od 200 mg u 8 ispitanika s teškim oštećenjem funkcije bubrega definiranim kao eGFR <30 ml/min, Cmax je bio u načelu neizmijenjen, a AUC0-∞ je bio izmijenjen za manje od 10% u usporedbi s 8 odgovarajućih zdravih kontrolnih ispitanika.
English: Lactic acidosis has not been reported in patients treated with tedizolid phosphate at the recommended treatment duration of 6 days.
Croatian: Laktacidoza nije zabilježena u bolesnika liječenih tedizolidfosfatom tijekom preporučenog trajanja liječenja od 6 dana.
English: These effects occurred at plasma tedizolid exposure levels (AUC) ≥3-fold greater than the expected human plasma exposure associated with the therapeutic dose.
Croatian: Ti su se učinci javili pri razinama izloženosti tedizolidu u plazmi (AUC) ≥3 puta većim od očekivane izloženosti u ljudskoj plazmi povezanoj s terapijskom dozom.
English: Oral and intravenous tedizolid phosphate is a prodrug that is rapidly converted by phosphatases to tedizolid, the microbiologically active moiety.
Croatian: Peroralni i intravenski tedizolidfosfat je predlijek koji fosfataze brzo pretvaraju u tedizolid, mikrobiološki aktivni spoj.
English: The mean steady state volume of distribution of tedizolid in healthy adults (n=8) following a single intravenous dose of tedizolid phosphate 200 mg ranged from 67 to 80 L.
Croatian: Srednji volumen distribucije tedizolida u stanju dinamičke ravnoteže u zdravih odraslih osoba (n=8) nakon jedne intravenske doze tedizolidfosfata od 200 mg varirao je od 67 do 80 l.
English: EU/1/15/991/002 1 vial EU/1/15/991/003 6 vials
Croatian: EU/1/15/991/002 1 bočica EU/1/15/991/003 6 bočica
English: These effects showed evidence of reversibility and occurred at plasma tedizolid exposure levels (AUC) ≥6-fold greater than the plasma exposure associated with the human therapeutic dose.
Croatian: Ti su se učinci pokazali reverzibilnima i javili su se pri razinama izloženosti tedizolidu u plazmi (AUC) ≥6 puta većim od izloženosti u plazmi povezanoj s ljudskom terapijskom dozom.
English: Table 1 Frequency of adverse reactions by System Organ Class in pooled Phase 3 comparative clinical studies
Croatian: Tablica 1 Učestalost nuspojava prema klasifikaciji organskih sustava u udruženim usporednim kliničkim ispitivanjima faze 3
English: The following adverse reactions have been identified in two comparative pivotal Phase 3 studies and one post-authorisation study with Sivextro (Table 1).
Croatian: Sljedeće su nuspojave zabilježene u dvama usporednim pivotalnim ispitivanjima faze 3 i jednom ispitivanju nakon dobivanja odobrenja za stavljanje lijeka u promet s lijekom Sivextro (Tablica 1).
English: It must be administered as an intravenous infusion only.
Croatian: Smije se primjenjivati isključivo intravenskom infuzijom.
English: Foetal developmental effects occurring in mice in the absence of maternal toxicity included reduced foetal weights and an increased incidence of costal cartilage fusion (an exacerbation of the normal genetic predisposition to sternal variations in the CD-1 strain of mice) at the high dose of 25 mg/kg/day (4-fold the estimated human exposure level based on AUCs).
Croatian: Učinci na fetalni razvoj koji se pojavljuju u miševa u odsustvu toksičnosti za majku uključivali su smanjenu fetalnu težinu i povećanu incidenciju fuzije rebrene hrskavice (pogoršanje normalne genetske predispozicije za sternalne promjene u mišjem soju CD-1) pri visokoj dozi od 25 mg/kg/dan (4 puta viša od procijenjene ljudske razine izloženosti na temelju AUC-a).
English: The reconstituted solution will be withdrawn from the vial and added to an infusion bag of 0.9% sodium chloride in the hospital.
Croatian: Rekonstituiranu otopinu treba izvući iz bočice i dodati u infuzijsku vrećicu 0,9%-tne otopine natrijevog klorida u bolnici.
English: Tedizolid was positive in an in vitro CHL cell chromosomal aberration assay, but negative for genotoxicity in other in vitro assays (Ames, mouse lymphoma mutagenicity) and in vivo in a mouse bone marrow micronucleus assay.
Croatian: Tedizolid je bio pozitivan u in vitro testu kromosomske aberacije u stanicama CHL, ali je bio negativan na genotoksičnost u drugim in vitro testovima (Ames, mutagenost mišjeg limfoma) i in vivo u mikronukleusnom testu na mišjoj koštanoj srži.
English: The reconstituted solution must be administered as an intravenous infusion only.
Croatian: Rekonstituirana otopina smije se primjenjivati isključivo intravenskom infuzijom.
English: It is available in 6 × 1 tablets in perforated unit-dose blisters.
Croatian: Lijek je dostupan u perforiranim blisterima s jediničnim dozama sa 6 × 1 tableta.
English: It is not known if Sivextro passes into breast milk in humans.
Croatian: Nije poznato izlučuje li se Sivextro u majčino mlijeko.
English: Contact your doctor, pharmacist or nearest hospital casualty department as soon as possible if you have taken more tablets than you should, and take your medicine with you.
Croatian: Ako uzmete više lijeka Sivextro nego što ste trebali Obratite se čim prije liječniku, ljekarniku ili hitnoj službi najbliže bolnice ako ste uzeli više tableta nego što ste trebali, i ponesite lijek sa sobom.
English: In rats, decreased foetal weights and increased skeletal variations including reduced ossification of the sternabrae, vertebrae, and skull were observed at the high dose of 15 mg/kg/day (6-fold the estimated human exposure based on AUCs) and were associated with maternal toxicity (reduced maternal body weights).
Croatian: U štakora, smanjene fetalne težine i povećane koštane promjene, uključujući smanjenu osifikaciju sternebrae, kralježaka i lubanje, opažene su pri visokoj dozi od 15 mg/kg/dan (6 puta viša od procijenjene ljudske izloženosti na temelju AUC-a) i bile su povezane s toksičnosti za majku (smanjene tjelesne težine majke).
English: Peel, then push
Croatian: Odvojite foliju, zatim protisnite
English: Lactic acidosis has been reported with the use of another member of the oxazolidinone class.
Croatian: Laktacidoza je prijavljena prilikom primjene drugog lijeka iz skupine oksazolidinona.
English: • The active substance is tedizolid phosphate.
Croatian: • Djelatna tvar je tedizolidfosfat.
English: The film coat of the tablet contains polyvinyl alcohol, titanium dioxide (E171), macrogol, talc and yellow iron oxide (E172).
Croatian: Ovojnica tablete poli(vinilni alkohol) titanijev dioksid (E171) makrogol talk željezov oksid, žuti (E172)
English: Sivextro is incompatible with any solutions containing divalent cations (e.g., Ca
Croatian: Sivextro je inkompatibilan sa svim otopinama koje sadrže dvovalentne katione (npr. Ca
English: 6 × 1 tablets in aluminum/Polyethylene Terephthalate (PET)/Paper foil and polyvinyl chloride (PVC)/polyvinylidene chloride (PVdC) clear film perforated child-resistant unit-dose blisters.
Croatian: 6 × 1 tableta u perforiranim blisterima sigurnima za djecu s jediničnim dozama od folije od aluminija/polietilentereftaleata (PET)/papira i prozirnog filma od polivinilklorida (PVC)/polivinilidenklorida (PVdC).
English: The no observed adverse effect levels (NOAELs) for foetal toxicity in mice (5 mg/kg/day) as well as maternal and foetal toxicity in rats (2.5 mg/kg/day) were associated with tedizolid plasma area under the curve (AUC) values approximately equivalent to the tedizolid AUC value associated with the oral human therapeutic dose.
Croatian: Razine izloženosti pri kojima nisu opaženi štetni učinci (engl. no observed adverse effect level, NOAEL) za fetalnu toksičnost u miševa (5 mg/kg/dan) niti toksičnost za majku te fetalnu toksičnost u štakora (2,5 mg/kg/dan) bile su povezane s vrijednostima površine ispod krivulje (AUC) tedizolida u plazmi koje su približno jednake vrijednosti AUC-a tedizolida povezanoj s peroralnom ljudskom terapijskom dozom.
English: The pharmacokinetics of tedizolid were evaluated in adolescent subjects (12 to 17 years; n=20) following administration of a single oral or IV dose of tedizolid phosphate 200 mg.
Croatian: Farmakokinetika tedizolida procijenjena je u ispitanika u adolescentnoj dobi (od 12 do 17 godina; n=20) nakon primjene jednokratne peroralne ili intravenske doze tedizolidfosfata od 200 mg.
English: Medicinal products inhibiting peristalsis are contraindicated in this situation.
Croatian: U toj je situaciji kontraindicirana primjena lijekova koji inhibiraju crijevnu peristaltiku.
English: Peak plasma tedizolid concentrations are achieved within approximately 3 hours after dosing after oral administration of tedizolid phosphate under fasted conditions.
Croatian: Vršne koncentracije tedizolida u plazmi dostižu se približno 3 sata nakon doze tedizolidfosfata primijenjene peroralno natašte.
English: What Sivextro looks like and contents of the pack Sivextro is a white to off-white powder for concentrate for solution for infusion in a glass vial.
Croatian: Sivextro je bijeli do bjelkasti prašak za koncentrat za otopinu za infuziju u staklenoj bočici.
English: Therefore, orally administered tedizolid phosphate can result in inhibition of BCRP at the intestinal level.
Croatian: Stoga, peroralna primjena tedizolidfosfata može rezultirati inhibicijom BCRP-a na razini crijeva.
English: Patients should not take a double dose to compensate for a missed dose.
Croatian: Bolesnik ne smije uzeti dvostruku dozu kako bi nadoknadio propuštenu dozu.
English: Aseptic technique must be followed in preparing the infusion solution.
Croatian: Za pripremu infuzijske otopine mora se koristiti aseptička tehnika.
English: Tedizolid is bacteriostatic against enterococci, staphylococci, and streptococci in vitro.
Croatian: Tedizolid ima bakteriostatsko djelovanje na enterokoke, stafilokoke i streptokoke in vitro.
English: Monoamine oxidase inhibition
Croatian: Inhibicija monoaminoksidaze
English: • Itching (including itching due to allergic reaction), hair loss, acne, red and/or itchy rash or hives,
Croatian: • svrbež (uključujući svrbež zbog alergijske reakcije), gubitak kose, akne, crveni osip i/ili osip praćen svrbežom ili koprivnjača, pretjerano znojenje
English: A double dose should not be given to compensate for a missed dose.
Croatian: Ne smije mu se dati dvostruka doza kako bi se nadoknadila propuštena doza.
English: Sivextro contains sodium
Croatian: Sivextro sadrži natrij
English: See Other medicines and Sivextro for examples.
Croatian: Za primjere pogledajte dio Drugi lijekovi i Sivextro.
English: What you need to know before you take Sivextro
Croatian: Što morate znati prije nego počnete uzimati Sivextro
English: In ABSSSI, the types of infections treated were confined to cellulitis/erysipelas or major cutaneous abscesses, and wound infections only.
Croatian: U ispitivanju akutnih bakterijskih infekcija kože i kožnih struktura, vrste liječenih infekcija bile su ograničene samo na celulitis/erizipel ili veće kožne apscese i infekcije rana.
English: Yellow iron oxide (E172)
Croatian: makrogol, talk i žuti željezov oksid (E172).
English: Tedizolid phosphate was negative for genotoxicity in all in vitro assays (bacterial reverse mutation [Ames], Chinese hamster lung [CHL] cell chromosomal aberration) and in all in vivo tests (mouse bone marrow micronucleus, rat liver unscheduled DNA synthesis).
Croatian: Tedizolidfosfat nije pokazao genotoksičnost u svim in vitro testovima (test reverzne mutacije bakterija [Ames], test kromosomske aberacije u stanicama pluća kineskog hrčka [CHL]) i u svim in vivo testovima (mikronukleusni test na mišjoj koštanoj srži, neplanirana sinteza DNK na stanicama jetre štakora).
English: Tedizolid, generated from tedizolid phosphate after metabolic activation (in vitro and in vivo), was also tested for genotoxicity.
Croatian: Također je ispitana genotoksičnost tedizolida, koji se stvara iz tedizolidfosfata nakon metaboličke aktivacije (in vitro i in vivo).
English: Aseptic technique must be followed when preparing the infusion solution.
Croatian: Tijekom pripreme infuzijske otopine mora se koristiti aseptička tehnika.