FrancophonIA/ELRC3.0 huggingface dataset:
English: 12-month analysis
Slovenian: Analiza po 12 mesecih
English: Nearly all patients experienced some degree of CRS.
Slovenian: Pri skoraj vseh bolnikih se je pojavila določena stopnja CRS.
English: The number of anti-CD19 CAR T cells in the blood was positively associated with objective response (CR or PR).
Slovenian: Število anti-CD19 CAR T-celic v krvi je bilo pozitivno povezano z objektivnim odzivom (CR ali PR).
English: If you miss any appointments, call your doctor or the qualified clinical facility as soon as possible to reschedule your appointment.
Slovenian: Če izpustite termin za obisk, čim prej pokličite zdravnika ali usposobljeno klinično ustanovo, da termin prestavite.
English: • Prophylactic use of systemic corticosteroids is not recommended as it may interfere with the activity of YESCARTA.
Slovenian: • Profilaktične uporabe sistemskih kortikosteroidov se ne priporoča, saj lahko ovira aktivnost zdravila YESCARTA.
English: The requirements for submission of PSUR for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Slovenian: • Redno posodobljena poročila o varnosti zdravila (PSUR) Zahteve glede predložitve PSUR za to zdravilo so določene v seznamu referenčnih datumov EU (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES, in vseh kasnejših posodobitvah, objavljenih na evropskem spletnem portalu o zdravilih.
English: Do not donate blood, organs, tissues or cells for transplants.
Slovenian: Ne darujte krvi, organov, tkiva ali celic za presaditev.
English: Dysphagia is a recognised symptom of encephalopathy which is currently listed in the product information; however, dysphagia can lead to serious complications and may require specific clinical measures.
Slovenian: Disfagija je znan simptom encefalopatije, ki je trenutno naveden v informacijah o zdravilu; vendar pa lahko disfagija vodi do resnih zapletov, zaradi katerih so potrebni posebni klinični ukrepi.
English: Before you are given YESCARTA tell your doctor or nurse if you are taking any medicines that weaken your immune system such as corticosteroids, since these medicines may interfere with the effect of YESCARTA.
Slovenian: Preden boste dobili zdravilo YESCARTA, povejte zdravniku ali medicinski sestri, če jemljete kakršna koli zdravila, ki slabijo vaš imunski sistem, kot so kortikosteroidi, saj lahko ta zdravila vplivajo na učinek zdravila YESCARTA.
English: Peak elevation was observed within the first 14 days after infusion, and levels generally returned to baseline within 28 days.
Slovenian: Največje zvišanje so opazili v prvih 14 dneh po infundiranju, ravni pa so se na izhodiščne običajno vrnile v 28 dneh.
English: The ORR was prespecified to be tested in the first 92 treated patients and was significantly higher than the prespecified rate of 20% (P < 0.0001).
Slovenian: ORR je bil določen vnaprej in testiran pri prvih 92 zdravljenih bolnikih; rezultat je bil značilno večji od vnaprej določene stopnje 20 % (P < 0,0001).
English: YESCARTA will always be given to you by a healthcare professional.
Slovenian: Zdravilo YESCARTA vam bo vedno dal zdravstveni delavec.
English: Non-interventional post-authorisation safety study (PASS): In order to assess the safety profile including long term safety in patients with B-lymphocyte malignancies treated with axicabtagene ciloleucel in the post marketing setting, the applicant should conduct and submit a study based on a registry.
Slovenian: Neintervencijska študija o varnosti zdravila po pridobitvi dovoljenja za promet z zdravilom (PASS): Za ocenitev profila varnosti, vključno z dolgotrajno varnostjo bolnikov z malignimi obolenji B-limfocitov, zdravljenih z aksicabtagen ciloleucelom v obdobju trženja, mora vlagatelj izvesti in predložiti študijo na podlagi registra.
English: These events were considered as syndromes of neurologic toxicity, an important identified risk of axicabtagene ciloleucel use.
Slovenian: Ti dogodki so bili obravnavani kot sindromi nevrološke toksičnosti, ki je pomembno ugotovljeno tveganje pri uporabi aksicabtagen ciloleucela.
English: - have low blood cell levels (blood counts).
Slovenian: - če imate nizke ravni krvnih celic (števila krvnih celic).
English: Your doctor will recommend that you return to the hospital daily for at least 10 days and will consider whether you need to stay at the hospital as an in-patient for the first 10 days after infusion.
Slovenian: Zdravnik vam bo priporočil, da se v bolnišnico vsak dan vračate vsaj 10 dni, in razmislil o tem, da vas prvih 10 dni po infundiranju hospitalizira.
English: 24-month analysis
Slovenian: Analiza po 24 mesecih
English: Infections occurred in 39% of patients in ZUMA-1.
Slovenian: Okužbe so se pojavile pri 39 % bolnikov v študiji ZUMA-1.
English: Some of your white blood cells are separated from your blood and the rest of your blood is returned to your vein.
Slovenian: Nekatere bele krvne celice se izločijo iz krvi, nato pa se preostanek krvi vrne v žilo.
English: One cryostorage bag is individually packed in a shipping cassette.
Slovenian: Vsaka vreča za krioshranjevanje je posamično pakirana v transportno kaseto.
English: Forty-seven patients were evaluable for MYC, BCL-2, and BCL-6 status.
Slovenian: Pri 47 bolnikih je bilo mogoče oceniti status MYC, BCL-2 in BCL-6.
English: Outcomes were consistent between patients with Eastern Cooperative Oncology Group (ECOG) of 0 and 1 and by sex.
Slovenian: Izidi med bolniki s statusom 0 in 1 po Eastern Cooperative Oncology Group (ECOG) in po spolu so bili skladni.
English: See section 2 “YESCARTA contains sodium”.
Slovenian: Glejte poglavje 2 »Zdravilo YESCARTA vsebuje natrij«.
English: YESCARTA should only be given if the results show you are not pregnant.
Slovenian: Zdravilo YESCARTA lahko dobite samo, če rezultat testa pokaže, da niste noseči.
English: The anticipated metabolic products are typical cellular degradation products resulting from normal cellular clearance mechanisms.
Slovenian: Pričakovani presnovni produkti so tipični produkti celične razgradnje z običajnimi mehanizmi celičnega očistka.
English: • Your doctor or nurse will give you a single infusion of YESCARTA into your vein for approximately 30 minutes.
Slovenian: • Zdravnik ali medicinska sestra vam bo dal/a eno infuzijo zdravila YESCARTA v veno, kar bo trajalo približno 30 minut.
English: This medicine contains 300 mg sodium (main component of cooking/table salt) in each infusion.
Slovenian: To zdravilo vsebuje 300 mg natrija (glavna sestavina soli za kuhanje/namizne soli) v eni infuziji.
English: YESCARTA has major influence on the ability to drive and use machines.
Slovenian: Zdravilo YESCARTA ima pomemben vpliv na sposobnost vožnje in upravljanja strojev.
English: Precautions to be taken before handling or administering the medicinal product This medicinal product contains genetically modified human blood cells.
Slovenian: Previdnostni ukrepi, potrebni pred ravnanjem z zdravilom ali dajanjem zdravila To zdravilo vsebuje gensko spremenjene človeške krvne celice.
English: Of 111 patients who underwent leukapheresis, 101 received YESCARTA.
Slovenian: Od 111 bolnikov, pri katerih je bila opravljena levkafereza, je 101 prejel zdravilo YESCARTA.
English: Nine patients were not treated, primarily due to progressive disease or serious adverse events after enrolment and prior to cell delivery.
Slovenian: Devet bolnikov ni bilo zdravljenih, pretežno zaradi napredovanja bolezni ali resnega neželenega dogodka po vključitvi in pred vnosom celic.
English: Therefore, YESCARTA is not recommended for women who are pregnant, or for women of childbearing potential not using contraception.
Slovenian: Zdravila YESCARTA se zato ne priporoča pri ženskah, ki so noseče, ali pri ženskah v rodni dobi, ki ne uporabljajo kontracepcije.
English: Diagnosis of CRS requires excluding alternate causes of systemic inflammatory response, including infection.
Slovenian: Pri postavljanju diagnoze CRS je treba izključiti druge možne vzroke sistemskega vnetnega odziva, vključno z okužbo.
English: In the phase 1 part of ZUMA-1, 7 patients were treated.
Slovenian: V 1. fazi študije ZUMA-1 je bilo zdravljenih 7 bolnikov.
English: Administer tocilizumab per Table 1 for management of Grade 2 CRS.
Slovenian: Dajanje tocilizumaba v skladu s preglednico 1 za obravnavo CRS 2. stopnje.
English: In phase 2 of ZUMA-1, after YESCARTA infusion, pharmacodynamic responses were evaluated over a 4-week interval by measuring transient elevation of cytokines, chemokines, and other molecules in blood.
Slovenian: V 2. fazi študije ZUMA-1 so bili po infundiranju zdravila YESCARTA farmakodinamični odzivi ocenjeni v 4-tedenskem intervalu z merjenjem prehodnega povišanja ravni citokinov, kemokinov in drugih molekul v krvi.
English: • Additional risk minimisation measures
Slovenian: • Dodatni ukrepi za zmanjševanje tveganj Ključni elementi:
English: Patients were not required to be followed after they progressed; thus, the majority of patients with evaluable samples were responders.
Slovenian: Bolnikov, pri katerih je prišlo do napredovanja bolezni, ni bilo treba spremljati, zato je bila večina bolnikov z vzorci, ki jih je bilo mogoče oceniti, odzivnih na zdravljenje.
English: Levels of cytokines and chemokines such as IL-6, IL-8, IL-10, IL-15, TNF-α, IFN-γ, and IL2Rα were analyzed.
Slovenian: Analizirali so ravni citokinov in kemokinov, kot so IL-6, IL-8, IL-10, IL-15, TNF-α, IFN-γ in IL2Rα.
English: - If YESCARTA infusion is delayed for more than 2 weeks after you have received preparatory chemotherapy you may have to receive more preparative chemotherapy.
Slovenian: Če se infundiranje zdravila YESCARTA odloži za več kot 2 tedna po pripravljalni kemoterapiji, boste morda morali prejeti dodatno pripravljalno kemoterapijo.
English: Duration of Responsea, median (range) in months
Slovenian: Trajanje odzivaa, mediana (razpon) v mesecih
English: • Your white blood cells are frozen and sent away to make YESCARTA.
Slovenian: • Vaše bele krvne celice se zamrznejo in pošljejo v izdelavo zdravila YESCARTA.
English: Your doctor may need to take special care of you during your treatment with YESCARTA.
Slovenian: Morda bo moral biti zdravnik pri vas posebno pozoren med zdravljenjem z zdravilom YESCARTA.
English: • Infuse the entire content of the YESCARTA bag within 30 minutes by either gravity or a peristaltic pump.
Slovenian: • Celotno vsebino vreče zdravila YESCARTA infundirajte v 30 minutah s težnostno infuzijo ali s peristaltično črpalko.
English: Administer tocilizumab (c) 8 mg/kg intravenously over 1 hour (not to exceed 800 mg).
Slovenian: Dati je treba tocilizumab (c)8 mg/kg intravensko v obdobju 1 ure (ne več kot 800 mg).
English: You must receive YESCARTA infusion in a qualified clinical facility and be discharged only when your doctor thinks it is safe for you to go home.
Slovenian: Infuzijo zdravila YESCARTA morate prejeti v usposobljeni klinični ustanovi, iz katere boste odpuščeni, ko bo zdravnik menil, da lahko varno greste domov.
English: Too many of these abnormal white blood cells accumulate in your tissue and this is the cause of the symptoms you may have.
Slovenian: V vašem tkivu se nakopiči preveč teh nenormalnih belih krvnih celic, kar je vzrok simptomov, ki jih imate.
English: • Look for signs of graft-versus-host disease that can happen after a transplant.
Slovenian: • preveril znake bolezni presadka proti gostitelju, ki se lahko pojavi po presaditvi.
English: - have any lung, heart or blood pressure (low or raised) problems.
Slovenian: - če imate kakršne koli težave s pljuči, srcem ali krvnim tlakom (znižan ali zvišan).
English: There are insufficient exposure data to provide a recommendation concerning duration of contraception following treatment with YESCARTA.
Slovenian: Podatkov o izpostavljenosti ni dovolj, da bi lahko podali priporočilo glede dolžine uporabe kontracepcije po zdravljenju z zdravilom YESCARTA.
English: Therefore, the risk/benefit of YESCARTA has not been established in this population.
Slovenian: Zato razmerje med koristmi in tveganji zdravila YESCARTA za to populacijo ni bilo dokazano.
English: Summary of demographics for ZUMA-1 phase 2 (12 month analysis)
Slovenian: Preglednica 4: Povzetek demografskih značilnosti za 2. fazo ZUMA-1 (analiza po 12 mesecih) Kategorija
English: Patients should be monitored for signs and symptoms of neurologic adverse reactions (Table 2).
Slovenian: Bolnike je treba spremljati glede znakov in simptomov nevroloških neželenih učinkov (preglednica 2).
English: Kite Pharma, Inc. 2355 Utah Avenue El Segundo California CA 90245
Slovenian: Kite Pharma, Inc. 2355 Utah Avenue El Segundo
English: Age (years) Median (min, max)
Slovenian: Mediana (min, maks)
English: Tell your doctor immediately if you get any of the side effects listed above.
Slovenian: Zdravnika takoj obvestite, če opazite katerega od zgoraj navedenih neželenih učinkov.
English: However, YESCARTA infusion should begin within 30 minutes of thaw completion and the total YESCARTA infusion time should not exceed 30 minutes.
Slovenian: Vendar pa je z infundiranjem zdravila YESCARTA treba začeti v 30 minutah po koncu odtajanja, skupni čas infundiranja zdravila YESCARTA pa ne sme preseči 30 minut.
English: Pregnant women should be advised on the potential risks to the foetus.
Slovenian: Nosečnicam je treba svetovati o možnih tveganjih za plod.
English: Prior to receiving YESCARTA, you will be given other medicines such as preparative chemotherapy, which will allow your modified white blood cells in YESCARTA to multiply in your body when the medicine is given to you.
Slovenian: Preden boste prejeli zdravilo YESCARTA, boste dobili druga zdravila, kot je pripravljalna kemoterapija, ki bo omogočila, da se spremenjene bele krvne celice iz zdravila YESCARTA v vašem telesu namnožijo, ko prejmete zdravilo.
English: Do NOT use a leukodepleting filter.
Slovenian: NE uporabljajte filtra za odstranjevanje levkocitov.
English: A retrospective, patient-level, pooled analysis of outcomes in refractory aggressive NHL (N = 636) was conducted (Crump et al., 2017) to provide confirmation of the prespecified control response rate of 20% and historical context for interpreting the ZUMA-1 results.
Slovenian: Na ravni bolnikov so izvedli retrospektivno združeno analizo izidov neodzivnega, agresivnega NHL (N = 636) (Crump et al., 2017) za potrditev vnaprej določene kontrolne stopnje odziva 20 % in pridobitev zgodovinskega konteksta za razlago rezultatov ZUMA-1.
English: YESCARTA should not be used in children and adolescents below 18 years of age.
Slovenian: Zdravila YESCARTA ni dovoljeno uporabiti pri otrocih in mladostnikih, starih manj kot 18 let.
English: All treated (mITT) Cohort 1 + 2 (N = 101)
Slovenian: Vsi zdravljeni (mITT) Kohorta 1 + 2 (N = 101)
English: Additional Patient ID: Patient Name:
Slovenian: Kite ID št. bolnika: Dodatna ID št. bolnika: Ime bolnika:
English: Within each frequency grouping, adverse reactions are presented in the order of decreasing seriousness.
Slovenian: Znotraj vsake skupine pogostosti so neželeni učinki na zdravilo navedeni po padajoči resnosti.
English: Muscular weakness and leukoencephalopathy are listed in the axicabtagene ciloleucel product information.
Slovenian: Mišična šibkost in levkoencefalopatija sta že navedeni v informacijah o zdravilu za aksicabtagen ciloleucel.
English: TLS, which may be severe, has occasionally been observed.
Slovenian: Občasno so opazili TLS, ki je lahko resen.
English: • If you are pregnant or think you may be pregnant after treatment with YESCARTA, talk to your doctor immediately.
Slovenian: • Če ste noseči ali menite, da ste noseči po zdravljenju z zdravilom YESCARTA, se takoj posvetujte z zdravnikom.
English: During the 30 to 60 minutes before you are given YESCARTA you may be given other medicines.
Slovenian: Zdravila, ki se dajejo pred zdravljenjem z zdravilom YESCARTA V 30 do 60 minutah, preden prejmete zdravilo YESCARTA, boste morda prejeli druga zdravila.
English: Educational program - Prior to the launch of YESCARTA in each Member State the MAH must agree the content and format of the educational materials with the National Competent Authority.
Slovenian: Izobraževalni program - Pred prihodom zdravila YESCARTA na trg v vsaki državi članici mora imetnik dovoljenja za promet z zdravilom vsebino in obliko izobraževalnega gradiva dogovoriti z nacionalnim pristojnim organom.
English: All leukapheresed (ITT) Cohort 1 + 2 (N = 111)
Slovenian: Vsi z levkaferezo (ITT) Kohorta 1 + 2 (N = 111)
English: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before being given this medicine.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči, ali načrtujete zanositev, se posvetujte z zdravnikom ali medicinsko sestro, preden boste dobili to zdravilo.
English: In ZUMA-1, hypogammaglobulinaemia occurred in 16% of patients.
Slovenian: V študiji ZUMA-1 se je hiperbilirubinemija 1. stopnje pojavila pri 16 % bolnikov.
English: Analyses performed to identify associations between cytokine levels and incidence of CRS or neurologic events showed that higher levels (peak and AUC at 1 month) of IL-15, as well as IL-6, were associated with Grade 3 or higher neurologic adverse reactions and Grade 3 or higher CRS.
Slovenian: Analize, opravljene za ugotavljanje povezave med ravnmi citokina in pojavnostjo CRS ali nevroloških dogodkov, so pokazale, da so bile višje ravni (največja raven in AUC v 1. mesecu) za IL-15 in za IL-6, povezane z nevrološkimi neželenimi učinki 3. ali večje stopnje in CRS 3. ali večje stopnje.
English: For patients experiencing severe CRS, consider performing an echocardiogram to assess cardiac function.
Slovenian: Za bolnike, ki imajo resen CRS, je treba razmisliti o izvedbi ehokardiograma za oceno srčne funkcije.
English: Overall Survival, median (months) [95% CI]
Slovenian: Celokupno preživetje (OS), mediana (meseci) [95-% IZ]
English: 6229 EV Maastricht The Netherlands
Slovenian: 6229 EV Maastricht
English: The median duration of follow up was 27.1 months (still ongoing).
Slovenian: Mediana trajanja spremljanja je bila 27,1 meseca (še poteka).
English: This is to help prevent infusion reactions and fever.
Slovenian: Ta pomagajo pri preprečevanju reakcij na infuzijo in zvišane telesne temperature.
English: Unresolved serious adverse reactions (especially pulmonary reactions, cardiac reactions, or hypotension) including from preceding chemotherapies.
Slovenian: • Nerazrešeni resni neželeni učinki (zlasti reakcije, povezane s pljuči ali srcem, ali hipotenzija), vključno z učinki zaradi predhodnih kemoterapij.
English: Generally, safety and efficacy were similar between patients ≥ 65 years and patients < 65 years of age treated with
Slovenian: Na splošno sta bili varnost in učinkovitost pri bolnikih, starih ≥ 65 let, in pri bolnikih, starih < 65 let, zdravljenih z zdravilom YESCARTA, podobni.
English: • YESCARTA is the genetically modified version of your white blood cells.
Slovenian: • Zdravilo YESCARTA je gensko spremenjena različica vaših belih krvnih celic.
English: Active graft-versus-host disease (GVHD).
Slovenian: Aktivna bolezen presadka proti gostitelju (GVHD, graft-versus-host disease).
English: Five patients responded, including 4 CRs.
Slovenian: Pet bolnikov je bilo odzivnih, vključno s CR pri 4 bolnikih.
English: Summary of efficacy results for ZUMA-1 phase 2
Slovenian: Preglednica 5: Povzetek rezultatov učinkovitosti za 2. fazo študije ZUMA-1
English: The ORR was 26% [95% CI (21, 31)] and the CR rate was 7% [95% CI (3, 15)], with a median OS of 6.3 months.
Slovenian: Stopnja ORR je bila 26 % [95-% IZ (21; 31)] in stopnja CR je bila 7 % [95-% IZ (3; 15)], z mediano OS 6,3 meseca.
English: The analysis included patients who had not responded (SD or PD) to their last line of therapy, or had relapsed within 12 months after ASCT.
Slovenian: V analizo so bili vključeni bolniki, ki se niso odzvali (SB ali PB) na svoje zadnje zdravljenje ali pri katerih se je bolezen v 12 mesecih po ASCT ponovila.
English: Patients with active CNS disorder or inadequate renal, hepatic, pulmonary, or cardiac function are likely to be more vulnerable to the consequences of the adverse reactions described below and require special attention.
Slovenian: Bolniki z aktivno boleznijo osrednjega živčnega sistema ali nezadostno ledvično, jetrno, pljučno ali srčno funkcijo so verjetno bolj ranljivi za posledice spodaj opisanih neželenih učinkov in potrebujejo dodatno pozornost.
English: Work surfaces and material which have potentially been in contact with YESCARTA must be decontaminated with appropriate disinfectant.
Slovenian: Delovne površine in materiale, ki bi lahko bili v stiku z zdravilom YESCARTA, dekontaminirajte z ustreznim razkužilom.
English: In the event that a secondary malignancy occurs, contact the company to obtain instructions on patient samples to collect for testing.
Slovenian: V primeru pojava sekundarnega malignega obolenja se je treba povezati s podjetjem za pridobitev navodil o vzorcih, ki jih je treba pri bolniku odvzeti za testiranje.
English: The ORR results within PMBCL and DLBCL arising from follicular lymphoma were both 88%.
Slovenian: Rezultat ORR pri PMBCL in DLBCL, ki nastane iz folikularnega limfoma, je bil pri obeh 88 %.
English: Assessment of immunoglobulin levels and B-cells in newborns of mothers treated with YESCARTA should be considered.
Slovenian: Razmisliti je treba o oceni ravni imunoglobulina in B-celic pri novorojenčkih mater, zdravljenih z zdravilom YESCARTA.
English: What YESCARTA is and what it is used for
Slovenian: Kaj je zdravilo YESCARTA in za kaj ga uporabljamo
English: Patients should be monitored for signs and symptoms of infection before, during, and after YESCARTA infusion and treated appropriately.
Slovenian: Bolnike je treba spremljati glede znakov in simptomov okužb pred infundiranjem zdravila YESCARTA, med njim in po njem, ter jih ustrezno zdraviti.
English: (b) Refer to Table 2 for management of neurologic adverse reactions.
Slovenian: (b) Glejte preglednico 2 za obravnavo nevroloških neželenih učinkov.
English: • Plan to stay within proximity from the hospital where you were treated for at least 4 weeks after you have been given YESCARTA.
Slovenian: • Načrtujte zadrževanje v bližini bolnišnice, kjer ste se zdravili, še vsaj 4 tedne po prejemu zdravila YESCARTA.
English: There is no clinical experience in patients with active HIV, HBV or HCV infection.
Slovenian: Kliničnih izkušenj pri bolnikih z aktivno okužbo s HIV, HBV ali HCV ni.
English: Patients must have received at least prior anti-CD20 antibody therapy and an anthracycline containing regimen.
Slovenian: Bolniki so morali prejeti vsaj predhodno zdravljenje s protitelesi proti CD20 in režim, ki je vseboval antraciklin.
English: This is so your doctor can check if your treatment is working and help you if you have any side effects.
Slovenian: To zdravniku omogoči, da preverja delovanje zdravila in vam pomaga, če se pojavijo neželeni učinki.
English: The median duration of follow up was 27.4 months.
Slovenian: Mediana trajanja spremljanja je bila 27,4 meseca.
English: Febrile neutropenia was observed in 36% of patients after YESCARTA infusion.
Slovenian: Febrilno nevtropenijo so opazili pri 36 % bolnikov po infundiranju zdravila YESCARTA.
English: The anti-CD19 CAR-positive viable T cells are expanded and infused back into the patient, where they can recognise and eliminate CD19-expressing target cells.
Slovenian: Anti-CD19 CAR-pozitivne viabilne T-celice se ekspandirajo in infundirajo nazaj v bolnika, kjer prepoznajo in eliminirajo ciljne celice, ki izražajo CD19.
English: Due to the risks associated with YESCARTA treatment, infusion should be delayed if a patient has any of the following conditions:
Slovenian: Zaradi tveganj, povezanih z zdravljenjem z zdravilom YESCARTA, je treba z infundiranjem počakati, če se pri bolniku pojavi katero od naslednjih stanj:
English: • A leukodepleting filter must not be used.
Slovenian: • Filtra za odstranjevanje levkocitov ne smete uporabiti.
English: Thus, the infused CAR T cells are expected to be cleared over time.
Slovenian: Zato se čez čas pričakuje očistek infundiranih CAR T-celic.