FrancophonIA/ELRC3.0 huggingface dataset:
English: • How to use the daily tracker table (including examples of a completed daily tracker);
Slovenian: • Kako uporabljati preglednico v dnevnem sledilniku (vključno s primeri izpolnjenega dnevnega sledilnika);
English: Frequencies of occurrence of undesirable effects are defined as: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1000); very rare (< 1/10,000) and not known (cannot be estimated from the available data).
Slovenian: Pogostnosti neželenih učinkov so opredeljene kot: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000) in neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: CTN less than 500 pg/ml
Slovenian: CTN manj kot 500 pg/ml
English: c HR= Hazard Ratio.
Slovenian: c HR = razmerje ogroženosti.
English: Your doctor will discuss with you the benefits and risks of taking Caprelsa during this time.
Slovenian: Zdravnik se bo z vami pogovoril o koristih in tveganjih jemanja zdravila Caprelsa v teh obdobjih.
English: Therefore, RET mutation testing is recommended.
Slovenian: Zato je priporočljiv preskus za določitev mutacije RET.
English: First QTc prolongations occurred most often in the first 3 months of treatment, but continued to first occur after this time.
Slovenian: Prva podaljšanja intervala QT so se najpogosteje pojavljala v prvih 3 mesecih zdravljenja, a so se prvič pojavila tudi po preteku tega obdobja.
English: RET mutation status was obtained at the time of diagnosis in a majority of patients and could have changed since.
Slovenian: *status mutacije RET je bil pri večini bolnikov pridobljen ob postavitvi diagnoze in se je od tedaj lahko spremenil.
English: - It is important that you keep the Alert Card with you during treatment.
Slovenian: • Pomembno je, da imate opozorilno kartico pri sebi ves čas zdravljenja.
English: This cuts off the supply of food and oxygen to the tumour.
Slovenian: Tako prekine oskrbo tumorja s hranili in kisikom.
English: Do not take Caprelsa: - if you are allergic to vandetanib or any of the other ingredients of this medicine (listed in Section 6).
Slovenian: Ne jemljite zdravila Caprelsa če ste alergični na vandetanib ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Clinical efficacy in adults
Slovenian: Klinična učinkovitost pri odraslih
English: The analysis was performed using a logistic regression model with treatment as the only factor.
Slovenian: Analiza je bila narejena z modelom logistične regresije in zdravljenjem kot edinim faktorjem.
English: You will also find this information in the Patient Alert Card you have been given by your doctor.
Slovenian: Te informacije boste našli tudi v Opozorilni kartici za bolnika, ki vam jo je dal zdravnik.
English: If you have trouble swallowing the tablet
Slovenian: Če težko pogoltnete tableto
English: Disease control rate = response rate + stable disease at 24 weeks.
Slovenian: Delež obvladanja bolezni = delež odziva + stabilna bolezen po 24 tednih.
English: • If you have high blood pressure.
Slovenian: • če imate visok krvni tlak.
English: The treatment may either be given to your child as a once-daily dose, an every other day dosing or a repeating 7-day schedule as indicated in the dosing guide that has been given to you by your doctor.
Slovenian: Otrok lahko zdravilo dobiva enkrat na dan, vsak drugi dan ali v ponavljajoči se 7-dnevni shemi, kot je navedeno v vodniku za odmerjanje, ki vam ga je izročil zdravnik.
English: Some people who are taking Caprelsa become more sensitive to the sun.
Slovenian: Nekateri ljudje postanejo med jemanjem zdravila Caprelsa bolj občutljivi za sonce.
English: Eight percent of patients had a dose reduction due to QTc prolongation.
Slovenian: Osmim odstotkom bolnikov so zmanjšali odmerek zaradi podaljšanja intervala QTc.
English: The 300 mg daily dose can be reduced to 200 mg (two 100 mg tablets), and then to 100 mg if necessary.
Slovenian: Dnevni odmerek 300 mg je mogoče zmanjšati na 200 mg (dve 100-mg tableti) in potem na 100 mg, če je potrebno.
English: The remaining 49 patients (49%) were censored in the analysis of PFS.
Slovenian: Preostalih 49 bolnikov (49 %) je bilo izločenih iz analize PFS.
English: Only patients with CTN ≥ 500 pg/mL (conventional units) or ≥ 146.3 pmol/L (international standard units) were enrolled.
Slovenian: Vključeni so bili le tisti bolniki s CTN ≥ 500pg/ml (konvencionalne enote) ali ≥ 146,3 pmol/l (mednarodne standardne enote).
English: What to do if you forget to take a tablet depends on how long it is until your next dose.
Slovenian: Če pozabite vzeti tableto, je ukrepanje odvisno od tega, koliko časa je še do naslednjega odmerka.
English: The PFS primary endpoint, ORR and DCR were based on centralized, independent blinded review of the imaging data.
Slovenian: Primarni opazovani dogodek PFS ter ORR in DCR so temeljili na centraliziranem, neodvisnem in slepljenem pregledu slikovnih podatkov.
English: Any residues in the glass are to be mixed with half a glass of water and swallowed.
Slovenian: Ostanke v kozarcu je treba zmešati s pol kozarca vode in popiti.
English: Efficacy endpoint PFS HR (95%) confidence interval
Slovenian: Učinkovitost opazovanega dogodka PFS HR (95 %) interval zaupanja
English: The remaining 158 patients (68%) were censored in the analysis of PFS.
Slovenian: Preostalih 158 bolnikov (68 %) je bilo izločenih iz analize PFS.
English: These may be signs of a change in the electrical activitiy of your heart.
Slovenian: To so lahko znaki motene električne aktivnosti srca.
English: • Trouble sleeping (insomnia).
Slovenian: • težave s spanjem (nespečnost);
English: Periodic monitoring of alanine aminotransferase is recommended.
Slovenian: Priporočljivo je redno spremljanje alanin-aminotransferaze.
English: The risk of Torsades may be increased in patients with electrolyte imbalance (see section 4.8).
Slovenian: Tveganje za torsades je lahko večje pri bolnikih z elektrolitskim neravnovesjem (glejte poglavje 4.8).
English: This is because Caprelsa can affect the way some medicines work and some medicines can have an effect on Caprelsa.
Slovenian: Zdravilo Caprelsa namreč lahko vpliva na delovanje nekaterih zdravil in nekatera zdravila lahko vplivajo na zdravilo Caprelsa.
English: • Take half a glass of still (non-carbonated) water.
Slovenian: • Pripravite pol kozarca negazirane vode (vode brez mehurčkov).
English: If you have trouble swallowing the tablet, you can mix it with water as follows:
Slovenian: Če težko pogoltnete tableto, jo lahko raztopite v vodi takole:
English: It is important that you keep this Alert Card and show it to your partner or caregivers.
Slovenian: Pomembno je, da to opozorilno kartico za bolnika shranite in jo pokažete svojemu partnerju/partnerki ali tistim, ki skrbijo za vas.
English: The patient must be monitored appropriately.
Slovenian: Bolnika se mora ustrezno spremljati.
English: However, fatigue and blurred vision have been reported and those patients who experience these symptoms should observe caution when driving or using machines.
Slovenian: Vendar sta bila opisana utrujenost in zamegljen vid. Bolniki, ki se jim pojavita ta simptoma, morajo biti previdni pri upravljanju vozil in strojev.
English: ** including two deaths in patients with QTc > 550 ms (one due to sepsis and one due to heart failure)
Slovenian: ** vključno z dvema primeroma smrti bolnikov z intervalom QTc > 550 ms (eden zaradi sepse in drugi zaradi srčnega popuščanja).
English: • Stir the tablet until it has dispersed into the water.
Slovenian: • Tableto mešajte, dokler se ne raztopi v vodi.
English: b OR=Odds Ratio.
Slovenian: b OR = razmerje obetov.
English: The median PFS for patients randomised to placebo was 19.3 months.
Slovenian: Mediano PFS bolnikov, randomiziranih na placebo, je bilo 19,3 mesecev.
English: If high blood pressure cannot be controlled with medical management, vandetanib should not be restarted until the blood pressure is controlled medically.
Slovenian: Če visokega krvnega tlaka ni mogoče obvladati z medicinsko obravnavo, se vandetaniba ne sme začeti znova uporabljati, dokler krvni tlak ni urejen z zdravili.
English: • The general daily tracker for 14 days and blank copies of the daily tracker.
Slovenian: • Splošni dnevni sledilnik za 14 dni in prazni izvodi dnevnega sledilnika.
English: • If it is 12 hours or more until your next dose: Take the missed tablet as soon as you remember.
Slovenian: • Če je do naslednjega odmerka še 12 ur ali več: Vzemite pozabljeno tableto, čim se spomnite.
English: Vandetanib has shown no mutagenic or clastogenic potential.
Slovenian: Vandetanib ni pokazal mutagenega ali klastogenega potenciala.
English: The primary objective of this study was to demonstrate an improvement in progression-free survival (PFS) with vandetanib compared to placebo.
Slovenian: Primarni cilj študije je bil ugotoviti izboljšanje preživetja brez napredovanja (PFS - progression-free survival) z vandetanibom v primerjavi s placebom.
English: • Serious breathlessness, or sudden worsening breathlessness, possibly with a cough or a high temperature (fever).
Slovenian: • resno težko dihanje ali nenadno poslabšanje težkega dihanja, lahko s spremljajočim kašljem ali visoko telesno temperaturo (vročino).
English: Whilst the study size is small owing to the rarity of MTC in children, it is considered representative of the target population.
Slovenian: Velikost študije je majhna zaradi redkosti tega raka pri otrocih, vendar velja za reprezentativno za ciljno populacijo.
English: • Caprelsa may be taken with or without food.
Slovenian: • Zdravilo Caprelsa lahko vzamete s hrano ali brez nje.
English: This study included 331 patients with unresectable locally advanced or metastatic MTC.
Slovenian: Ta študija je zajela 331 bolnikov z neresektabilnim, lokalno napredovalim ali metastatskim MTC.
English: After having well tolerated the first 1 or 2 cycles of therapy (1 cycle = 28 days), the remaining patients continued on 100 mg/m2 of treatment.
Slovenian: Po dobrem prenašanju prvega ali drugega ciklusa zdravljenja (1 ciklus = 28 dni) so preostali bolniki nadaljevali zdravljenje z odmerkom 100 mg/m2.
English: Mild to moderate skin reactions can be managed by symptomatic treatment, or by dose reduction or interruption.
Slovenian: Blage do zmerne kožne reakcije je mogoče obvladati s simptomatskim zdravljenjem ali z zmanjšanjem odmerka ali s prekinitvijo uporabe.
English: • The summary of Product Characteristics (SmPC);
Slovenian: • Povzetek glavnih značilnosti zdravila (SmPC);
English: Caprelsa is indicated in adults, children and adolescents aged 5 years and older.
Slovenian: Zdravilo Caprelsa je indicirano pri odraslih, otrocih in mladostnikih, starih 5 let in starejših.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines that you buy without a prescription and herbal medicines.
Slovenian: Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo, tudi če ste ga dobili brez recepta, vključno s pripravki rastlinskega izvora.
English: This schedule should apply to the period after dose reduction due to QTc prolongation and after dose interruption for more than two weeks.
Slovenian: To časovno shemo je treba uporabiti v obdobju po zmanjšanju odmerka zaradi podaljšanja intervala QTc in po prekinitvi odmerjanja, ki je daljše od dveh tednov.
English: In rats, effects on teeth, kidney and skin were noted.
Slovenian: Pri podganah so ugotovili učinke na zobe, ledvice in kožo.
English: The side effects of Caprelsa are listed in Section 4.
Slovenian: Neželeni učinki zdravila Caprelsa so našteti v poglavju 4.
English: For more severe skin reactions (such as Stevens-Johnson syndrome), referral of the patient to seek urgent medical advice is recommended.
Slovenian: V primeru hujših kožnih reakcij (npr. Stevens-Johnsonovega sindroma) je bolnike priporočljivo napotiti na nujno zdravniško obravnavo.
English: Caprelsa may also act directly on cancer cells to kill them or slow down their growth.
Slovenian: Zdravilo Caprelsa morda deluje tudi neposredno na rakave celice in jih uniči ali upočasni njihovo rast.
English: (For vandetanib monitoring, see section 4.2 Posology and Method of administration and section 4.4 Special warnings and precautions for use).
Slovenian: (Za spremljanje vandetaniba glejte poglavje 4.2, "Odmerjanje in način uporabe", in poglavje 4.4, "Posebna opozorila in previdnostni ukrepi").
English: QTcF prolongation was > 20 ms in over 91% of patients, > 60 ms in 35%, > 100 ms in 1.7%.
Slovenian: Podaljšanje intervala QTcF je bilo > 20 ms pri več kot 91 % bolnikov, > 60 ms pri 35 %, > 100 ms pri 1,7 % bolnikov.
English: The doctor will tell you how many tablets of Caprelsa to give to your child.
Slovenian: Zdravnik vam bo povedal, koliko tablet zdravila Caprelsa morate dati otroku.
English: Adverse reactions associated with overdose are to be treated symptomatically; in particular, severe diarrhoea must be managed appropriately.
Slovenian: Neželene učinke, povezane s prevelikim odmerjanjem, je treba zdraviti simptomatsko; še zlasti je treba ustrezno obravnavati hudo drisko.
English: The secondary endpoints were evaluation of overall objective response rate (ORR), disease control rate (DCR) defined as, partial response (PR) or complete response (CR) or stable disease (SD) lasting at least 24 weeks, duration of response (DOR), time to worsening of pain based on Brief Pain Inventory (BPI) worst pain scale, and overall survival (OS).
Slovenian: Sekundarni opazovani dogodki so bili celotni delež objektivnega odziva (ORR - objective response rate), delež obvladanja bolezni (DCR - disease control rate) opredeljen kot delni odziv (PR - partial response) ali popolni odziv (CR - complete response) ali stabilna bolezen (SD - stable disease) v trajanju vsaj 24 mesecev, trajanje odziva (DOR - duration of response), čas do poslabšanja bolečin na podlagi lestvice najhujše bolečine vprašalnika BPI (brief pain inventory) in celokupno preživetje (OS - overall survival).
English: Treatment should only be continued in pregnant women if the potential benefit to the mother outweighs the risk to the foetus.
Slovenian: Zdravljenje nosečnice se sme nadaljevati le, če možna korist za mater jasno odtehta tveganje za plod.
English: However, RET status could not be tested in a large proportion of patients (mainly because of unavailable results for direct sequencing of DNA) and response rate was somewhat lower in the patients with unknown RET status compared with RET mutation positive status: 51.8% vs. 35.9 % respectively.
Slovenian: Kljub temu, statusa RET ni bilo mogoče določiti pri velikem deležu bolnikov (zlasti zaradi neuporabnosti rezultatov neposrednega določanja zaporedja DNA) in delež odziva je bil pri bolnikih z neznanim statusom RET, v primerjavi s pozitivnim statusom RET, nekoliko manjši: 51,8 % v primerjavi s 35,9 %.
English: Patients should be monitored for hypertension and controlled as appropriate.
Slovenian: Bolnike je treba spremljati glede hipertenzije in jo obravnavati kot je ustrezno.
English: Alanine aminotransferase elevations
Slovenian: Zvišanje alanin-aminotransferaze
English: Upon improvement, treatment should be resumed at a reduced dose (see sections 4.2 and 4.8).
Slovenian: Po izboljšanju je treba zdravilo znova uvesti v manjšem odmerku (glejte poglavji 4.2 in 4.8).
English: Women of childbearing potential must use effective contraception during therapy and for at least four months following the last dose.
Slovenian: Ženske v rodni dobi morajo med zdravljenjem, in še vsaj štiri mesece po zadnjem odmerku, uporabljati učinkovito kontracepcijo.
English: Your doctor may tell you to take Caprelsa at a lower or increased dose (such as two 100 mg tablets or one 100 mg tablet).
Slovenian: Zdravnik vam lahko naroči, da jemljite manjši ali višji odmerek zdravila Caprelsa (npr. dve 100-mg tableti ali eno 100-mg tableto).
English: Prior to launch of CAPRELSA in each Member State the Marketing Authorisation Holder (MAH) must agree about the content and format of the educational programme, including communication media, distribution modalities, and any other aspects of the programme, with the National Competent Authority.
Slovenian: Pred prihodom zdravila CAPRELSA na trg v vsaki državi članici se mora imetnik dovoljenja za promet z zdravilom (MAH) s pristojnim nacionalnim organom dogovoriti glede vsebine in oblike izobraževalnega programa, vključno s sredstvi obveščanja, načini razdeljevanja in vsemi drugimi vidiki programa.
English: Film-coating Hypromellose Macrogol (300) Titanium dioxide (E171)
Slovenian: Filmska obloga hipromeloza makrogol (300) titanov dioksid (E171)
English: Patients aged 5-18 years should be dosed according to the nomogram in Table 1.
Slovenian: Odmerek za bolnike v starosti od 5 do 18 let je treba določiti z nomogramom v preglednici 1.
English: months n-vandetanib 231 196 169 140 40 1 0 n-placebo 100 71 57 45 13 0 0 ____ vandetanib 300 mg, ------ placebo, y-axis=PFS, x-axis=time in months, n-vandetanib=number of patients at risk-vandetanib, n-placebo=number of patients at risk-placebo HR = 0.46, 95%CI (0.31-0.69), p = 0.0001
Slovenian: meseci n-vandetanib 231 196 169 140 40 1 0 n-placebo 100 71 57 45 13 0 0 ____ vandetanib 300 mg, ------ placebo, y-os=PFS, x-os=čas v mesecih, n-vandetanib=število bolnikov s tveganjem-vandetanib, n-placebo=število bolnikov s tveganjem-placebo HR = 0,46, 95 % IZ (0,31-0,69), p = 0,0001
English: QTc interval should be carefully assessed prior to initiation of treatment.
Slovenian: Pred začetkom zdravljenja je treba skrbno oceniti interval QTc.
English: Within a 21 day collection period after a single dose of 14C-vandetanib, approximately 69% was recovered with 44% in faeces and 25% in urine.
Slovenian: Med 21-dnevnim obdobjem zbiranja po enem samem odmerku 14C-vandetaniba, se ga je izločilo približno 69 %: 44 % v blatu in 25 % v urinu.
English: Patients / caregivers
Slovenian: Bolniki / Skrbniki
English: If it is less than 12 hours to the next dose, the patient should not take the missed dose.
Slovenian: Če je do naslednjega odmerka manj kot 12 ur, bolnik ne sme vzeti izpuščenega odmerka.
English: Before initiating vandetanib, this risk should be carefully considered in patients with risk factors such as hypertension or history of aneurysm.
Slovenian: Pred uvedbo vandetaniba je treba to tveganje skrbno preučiti pri bolnikih z dejavniki tveganja, kot sta hipertenzija ali anamneza anevrizme.
English: • If your doctor or pharmacist changes your dose of Caprelsa
Slovenian: • Če vam zdravnik ali farmacevt spremeni odmerek zdravila Caprelsa.
English: Patients were treated with vandetanib or placebo until they reached objective disease progression.
Slovenian: Bolnike so zdravili z vandetanibom ali placebom, dokler niso dosegli objektivnega napredovanja bolezni.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Slovenian: Imetnik dovoljenja za promet z zdravilom bo izvedel farmakovigilančne aktivnosti in ukrepe, podrobno opisane v sprejetem RMP, predloženem v modulu 1.8.2 dovoljenja za promet z zdravilom, in vseh nadaljnjih sprejetih posodobitvah RMP.
English: In ex vivo plasma samples from colorectal cancer patients at steady state exposure after 300 mg once daily, the mean percentage protein binding was 93.7% (range 92.2 to 95.7%).
Slovenian: V vzorcih plazme bolnikov s kolorektalnim rakom ex vivo, pri izpostavljenosti v stanju dinamičnega ravnovesja po odmerku 300 mg enkrat na dan, je bil povprečni odstotek vezave na beljakovine 93,7 % (razpon: 92,2 do 95,7 %).
English: In view of the associated risks, it is important to limit treatment with vandetanib to patients who are in real need for treatment, i.e. with a symptomatic-aggressive course of the disease.
Slovenian: Glede na tveganja je pomembno omejiti zdravljenje z vandetanibom na tiste bolnike, ki zares potrebujejo zdravljenje, tj. na tiste s simptomatsko-agresivnim razvojem bolezni.
English: Clinical efficacy in paediatric patients:
Slovenian: Klinična učinkovitost pri pediatričnih bolnikih:
English: • Dry eye.
Slovenian: • suho oko;
English: • The need to counsel patients about the risk of prolonged QTc and PRES and inform them of what symptoms and signs to be aware of and the actions to take;
Slovenian: • Potreba po svetovanju bolnikom glede tveganj za podaljšanje intervala QTc in PRES ter seznanitev bolnikov o simptomih in znakih na katere morajo biti pozorni ter kako je treba ukrepati.
English: Rate of change in biomarker levels such as of calcitonin (CTN) and/or carcinoembryonic antigen (CEA) as well as the rate of change of tumour volume during watchful waiting might help to identify not only patients in need for treatment but also the optimal moment to commence treatment with vandetanib.
Slovenian: Hitrost spreminjanja ravni biokemičnih označevalcev kot je kalcitonin (CTN) in/ali karcinoembrionski antigen (CEA), kakor tudi hitrost spreminjanja volumna tumorja med skrbnim opazovanjem lahko pripomorejo k določitvi ne le bolnikov, ki potrebujejo zdravljenje, temveč tudi optimalnega trenutka za začetek zdravljenja z vandetanibom.
English: They are seen in 8% of people taking Caprelsa for medullary thyroid cancer.
Slovenian: Pojavijo se pri 8 % oseb, ki zaradi medularnega raka ščitnice jemljejo zdravilo Caprelsa.
English: No adjustment in starting dose is required for elderly patients.
Slovenian: Starejšim bolnikom začetnega odmerka ni potrebno prilagoditi.
English: - The re-evaluation of treatment efficacy in RET-negative patients based on the re-analysis of archived tumour samples from the pivotal study D4200C00058.
Slovenian: -Ponovno oceno koristi in tveganj zdravljenja pri RET-negativnih bolnikih na podlagi ponovne analize arhiviranih vzorcev tumorjev iz pivotne študije D4200C00058.
English: While you are taking Caprelsa, protect yourself when you go outside by always using sunscreen and wearing clothes to avoid exposure to the sun.
Slovenian: Med jemanjem zdravila Caprelsa se zaščitite, kadar greste ven, tako da vedno uporabite sredstvo za sončenje in nosite oblačila, ki bodo preprečila izpostavljenost soncu.
English: Monitoring of your blood and your heart:
Slovenian: Kontrole krvi in srca
English: Results according to RET status (positive, unknown and RET M918T mutation negative definition) are presented in Table 4.
Slovenian: Rezultati glede na status RET (določen kot pozitiven, neznan in negativen glede na mutacijo RET M918T) so predstavljeni v Preglednici 4.
English: The majority of elevations resolve while continuing treatment, others usually resolve after a 1-2 week interruption in therapy.
Slovenian: Večina zvišanj med nadaljnjim zdravljenjem mine, druga po navadi minejo po 1 do 2 tednih prenehanja zdravljenja.
English: • pentamidine (used to treat infection)
Slovenian: • pentamidin (uporablja se za zdravljenje okužbe)
English: Do not take Caprelsa if any of the above applies to you.
Slovenian: Ne vzemite zdravila Caprelsa, če kaj od naštetega velja za vas.
English: No studies to establish the effects of vandetanib on ability to drive and use machines have been conducted.
Slovenian: Študij o vplivu vandetaniba na sposobnost vožnje in upravljanja strojev niso izvedli.
English: Considering the data available in adult patients with renal impairment:
Slovenian: Upoštevaje podatke, ki so na voljo za odrasle bolnike z okvaro ledvic:
English: Prolongation of ECG QTc interval(*) (**)
Slovenian: Srčne bolezni podaljšanje intervala QTc (*)
English: Actually 79 patients were identified by absence of an M918T mutation and no RET mutation identified at any of the other 6 exons tested but in 71 of such patients sequencing of the 6 exons was incomplete.
Slovenian: Dejansko je bilo 79 bolnikov istovetnih za odsotnost mutacije M918T in mutacija RET ni bila istovetena pri nobenem od 6 preskušanih eksonov, vendar je pri 71 tovrstnih bolnikih določanje zaporedja v 6 eksonih bilo nepopolno.