FrancophonIA/ELRC3.0 huggingface dataset:
English: • Medicines that reduce the ability of blood to clot, such as anticoagulants (e.g. warfarin and heparin), dipyridamole, acetylsalicylic acid or medicines to treat pain and inflammation, since using these medicines with asparaginase may increase the risk of bleeding.
Danish: • Lægemidler, der nedsætter blodets evne til at størkne, såsom antikoagulantia (f.eks. warfarin og heparin), dipyridamol, acetylsalicylsyre eller lægemidler til behandling af smerter og betændelse, da anvendelsen af disse lægemidler sammen med asparaginase kan øge risikoen for blødninger.
English: Disseminated intravascular coagulation (DIC), anaemia, leukopenia, thrombocytopenia
Danish: Dissemineret intravaskulær koagulation (DIC), anæmi, leukopeni, trombocytopeni
English: *Including all allergic reactions within 12 hours after asparaginase infusion and all adverse events with CTCAE terms syncope (fainting), hypotension, rash, flushing, pruritus, dyspnoea, injection site reaction or airway obstruction within 24 hours after asparaginase infusion
Danish: *Herunder alle allergiske reaktioner inden for 12 timer efter asparaginaseinfusion, og alle uønskede hændelser med CTCAE-termerne synkope (besvimelse), hypotension, udslæt, rødme, pruritus, dyspnø, reaktioner på injektionsstedet eller luftvejsobstruktion inden for 24 timer efter asparaginaseinfusion
English: Asparaginase hydrolyses asparagine to aspartic acid and ammonia.
Danish: Aasparaginase hydrolyserer asparagin til asparaginsyre og ammoniak.
English: Increase in amylase, lipase, abnormal electroencephalogram (EEG) (reduced alpha wave activity, increased theta and delta wave activity)
Danish: Forhøjelse i amylase, lipase, unormalt elektroencefalogram (EEG) (reduceret alfabølge-aktivitet, forhøjet theta- og deltabølge-aktivitet)
English: Adverse central nervous system reactions observed in patients treated with asparaginase-containing therapy protocols include changes in EEG, seizures, dizziness, somnolence, coma and headache.
Danish: Bivirkninger i centralnervesystemet observeret hos patienter i behandling med protokoller indeholdende asparaginase omfatter ændringer i EEG, krampeanfald, svimmelhed, døsighed, koma og hovedpine.
English: Glucocorticoids
Danish: Glukokortikoider
English: Table 2: Frequency of patients with allergic reactions (MC-ASP.5/ALL; Safety analysis set) Treatment group
Danish: Tabel 2: Hyppighed af patienter med allergiske reaktioner (MC-ASP.5/ALL, sikkerhedsanalysesæt)
English: However, in rare cases it can result in diabetic ketoacidosis.
Danish: I sjældne tilfælde kan det imidlertid føre til diabetisk ketoacidose.
English: Very rare Secondary hypothyroidism, hypoparathyroidism
Danish: Meget sjælden Sekundær hypotyreoidisme, hypoparatyreoidisme
English: • hepatotoxicity,
Danish: • hepatotoksicitet,
English: Inhibition of protein synthesis secondary to the asparaginase-induced depletion of asparagine has been shown to attenuate the cytotoxic effect of MTX which requires cell replication for its antineoplastic activity.
Danish: Hæmning af proteinsyntesen sekundært til asparaginase-induceret tømning af asparagin har vist sig at attenuere den cytotoksiske virkning af MTX, som kræver cellereplikation for den antineoplastiske aktivitet.
English: Even those few patients with trough asparaginase serum activity levels of 10 - 100 U/l usually experienced complete asparagine depletion in serum and CSF.
Danish: Selv de få patienter med minimalt aktivitetsniveau af asparaginase i serum på 10 - 100 E/l oplevede normalt fuldstændig asparagin-tømning i serum og CSF.
English: Neurological signs and symptoms including agitation, dizziness and somnolence
Danish: Neurologiske tegn og symptomer, herunder ophidselse, svimmelhed og døsighed
English: 0.053 (0.043 - 0.178) l/h
Danish: 0.053 (0.043 - 0.178) l/t
English: To dissolve the powder, 3.7 ml of water for injection is carefully squirted against the inner wall of the vial with an injection syringe (do not squirt directly on or into the powder).
Danish: 3,7 ml vand til injektionsvæsker sprøjtes forsigtigt mod hætteglassets inderside med en injektionssprøjte (der må ikke sprøjtes direkte på eller ind i pulveret).
English: No case of asparaginase overdose with clinical symptoms has been reported.
Danish: Der er ikke rapporteret tilfælde af overdosering med asparaginase med kliniske symptomer.
English: The active substance is asparaginase.
Danish: • Aktivt stof: asparaginase.
English: In a clinical trial in children with de novo ALL (study MC-ASP.4/ALL) it was shown that immediately after the end of infusion of asparaginase mean asparagine concentrations in serum dropped from the pre-dose concentrations of about 40 µM to below the lower limit of quantification of the bioanalytical method (< 0.5 µM).
Danish: I et klinisk studie af børn med de novo ALL (studie MC-ASP.4/ALL) blev det vist, at de gennemsnitlige asparaginkoncentrationer i serum faldt umiddelbart efter endt infusion med asparaginase fra koncentrationer før dosis på ca. 40 µM til under den nedre kvantificeringsgrænse for den bioanalytiske metode (< 0,5 µM).
English: • blood clotting disorders (bleeding or formation of blood clots),
Danish: • blodstørkningsforstyrrelser (blødning eller dannelse af blodpropper),
English: 3,527 (2,231 - 4,526) U/l
Danish: 3.527 (2.231 - 4.526) E/l
English: • allergic reactions including wheezing (bronchospasm) or difficulty in breathing
Danish: • allergiske reaktioner, herunder hvæsende vejrtrækning (bronkospasme) eller vejrtrækningsbesvær
English: LIST OF EXCIPIENTS Excipient: sucrose.
Danish: LISTE OVER HJÆLPESTOFFER Hjælpestof: saccharose.
English: How to use Spectrila
Danish: Sådan skal du bruge Spectrila
English: Asparaginase-induced tumour cell destruction may release large amounts of uric acid, resulting in hyperuricaemia.
Danish: Asparaginase-induceret tumorcelledestruktion kan frigive store mængder urinsyre og føre til hyperurikæmi.
English: • Glucocorticoids (anti-inflammation medicines that dampen down your immune system) since the simultaneous use of glucocorticoids and asparaginase may increase the formation of blood clots (thrombosis).
Danish: • Glukokortikoider (antiinflammatoriske lægemidler, der dæmper dit immunsystem), da anvendelse af glukokortikoider sammen med asparaginase kan øge dannelsen af blodpropper (trombose).
English: In rare cases, diabetic ketoacidosis has been reported.
Danish: I sjældne tilfælde er der blevet rapporteret diabetisk ketoacidose.
English: Additionally it may decrease insulin secretion from pancreatic β-cells and impair insulin receptor function.
Danish: Desuden kan det nedsætte insulinsecerneringen fra β-celler i pankreas og hæmme funktionen af insulinreceptorer.
English: • inflammation of the pancreas, which causes severe pain in the abdomen and back,
Danish: • betændelse i bugspytkirtlen, der forårsager svære smerter i mave og ryg,
English: Aggressive alkalinisation of the urine and use of allopurinol can prevent urate nephropathy.
Danish: En aggressiv alkalisering af urinen og anvendelsen af allopurinol kan forhindre uratnefropati.
English: A method other than oral contraceptives should be used in women of childbearing potential.
Danish: Der bør anvendes en anden metode end oral kontraception hos kvinder i den fertile alder.
English: Therefore, Spectrila must not be used during breast-feeding.
Danish: Derfor må Spectrila ikke anvendes under amning.
English: Dissolution of the contents is achieved by slow turning (avoid froth formation due to shaking).
Danish: Indholdet opløses ved at dreje hætteglasset langsomt rundt (undgå skumdannelse fra omrystning).
English: Reversible posterior leukoencephalopathy syndrome (characterised by headache, confusion, seizures and visual loss) may require blood-pressure lowering medicines and in case of seizure, anti-epileptic treatment.
Danish: Reversibelt posteriort leukoencefalopatisyndrom (karakteriseret ved hovedpine, forvirring, krampeanfald og synstab) kan kræve blodtrykssænkende medicin og i tilfælde af krampeanfald, som følge af antiepileptisk behandling.
English: Spectrila is usually employed as part of combination chemotherapy protocols with other antineoplastic agents (see also section 4.5).
Danish: Spectrila anvendes normalt som en del af protokoller med kemoterapi af kombinationstypen sammen med andre antineoplastiske stoffer (se også pkt.
English: 17.33 (12.54 - 22.91) h
Danish: 17,33 (12,54 - 22,91) t
English: Mild to moderate changes in blood lipid values (e.g. increased or decreased cholesterol, increased triglyceride, increased VLDL fraction and decreased LDL, increased lipoprotein lipase activity) are very commonly observed in patients treated with asparaginase, which in most cases present without clinical symptoms.
Danish: Lette til moderate ændringer i lipidværdier i blodet (f.eks. forhøjet eller nedsat kolesterol, forhøjet triglycerid, forhøjet VLDL-fraktion og nedsat LDL, forhøjet lipoprotein lipaseaktivitet) observeres meget hyppigt hos patienter i behandling med asparaginase, hvilket i de fleste tilfælde er til stede uden kliniske symptomer.
English: It is unknown whether asparaginase is excreted into human breast milk.
Danish: Det er ukendt, om asparaginase udskilles i human brystmælk.
English: Ischaemic stroke, reversible posterior leukoencephalopathy syndrome (RPLS), convulsion, disturbances in consciousness including coma
Danish: Iskæmisk slagtilfælde, reversibelt posteriort leukoencefalopatisyndrom (RPLS), krampeanfald, bevidsthedsforstyrrelser, herunder koma
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each vial contains 10,000 units of asparaginase*.
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Hvert hætteglas indeholder 10.000 enheder asparaginase*.
English: Symptoms of RPLS essentially include elevated blood pressure, seizures, headaches, changes in mental state and acute visual impairment (primarily cortical blindness or homonymous hemianopsia).
Danish: Symptomer på RPLS omfatter i alt væsentligt forhøjet blodtryk, krampeanfald, hovedpine, ændring af psykisk tilstand og akut synsnedsættelse (primært kortikal blindhed eller homonym hemianopsi).
English: Hyperammonaemia and sinus vein thrombosis may need to be excluded.
Danish: Det kan være nødvendigt at udelukke hyperammonæmi og sinusvenetrombose.
English: Nausea/vomiting are very commonly observed in patients treated with asparaginase-containing treatment regimens but are usually mild.
Danish: Kvalme/opkastning observeres meget almindeligt hos patienter i behandlingsprogrammer indeholdende asparaginase, men det er normalt af en let karakter.
English: A higher risk of thrombosis during induction therapy with asparaginase and prednisone was seen in children with a genetic prothrombotic risk factor (factor V G1691A-mutations, prothrombin G20210A-variation, methylenetetrahydrofolate reductase [MTHFR] T677T-genotype, increased lipoprotein A, hyperhomocysteinaemia).
Danish: Der blev observeret en større risiko for trombose i løbet af induktionsbehandlingen med asparaginase og prednison hos børn med en genetisk protrombotisk risikofaktor (faktor V G1691A-mutationer, protrombin G20210A-variation, methylentetrahydrofolat-reduktase [MTHFR] T677T-genotype, forhøjet lipoprotein A, hyperhomocysteinæmi).
English: MARKETING AUTHORISATION NUMBER(S) EU/1/15/1072/001
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (-NUMRE) EU/1/15/1072/001
English: 7,500 U/m² BSA.
Danish: 7.500 E/m² BSA.
English: • Hypersensitivity to the active substance, any native (non-pegylated) E. coli-asparaginase preparation or to any of the excipients listed in section 6.1.
Danish: • Overfølsomhed over for det aktive stof, alle naturligt forekommende (ikke pegylerede) E. coli asparaginase-præparater eller over for et eller flere af hjælpestofferne anført i pkt.
English: The reconstituted solution may exhibit a slight opalescence.
Danish: Den rekonstituerede opløsning kan være let uigennemsigtig.
English: • acute pancreatitis,
Danish: • akut pankreatitis,
English: Diarrhoea, nausea, vomiting, abdominal pain Common
Danish: Diarré, kvalme, opkastning, abdominalsmerter Almindelig
English: In an uncontrolled clinical trial (study MC-ASP.6/INF), 12 infants (median age [range] at time of first infusion: 6 months [0.5 - 12.2 months]) with de novo ALL were treated with Spectrila within the
Danish: I et ikke kontrolleret klinisk studie (studie MC-ASP.6/INF) blev 12 spædbørn (medianalder [interval] på tidspunktet for første infusion: 6 måneder [0,5 - 12,2 måneder]) med de novo ALL behandlet med Spectrila i INTERFANT-06-protokollen.
English: Difference (95 % CIa)
Danish: Kan ikke evalueres / ikke kendt Forskel (95 % CIa)
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu.
Danish: DATO FOR ÆNDRING AF TEKSTEN Yderligere oplysninger om dette lægemiddel findes på Det Europæiske Lægemiddelagenturs http://www.ema.europa.eu hjemmeside.
English: Anorexia, loss of appetite, abdominal cramps, diarrhoea and weight loss have also been reported.
Danish: Anoreksi, appetitløshed, abdominalkramper, diarré og vægttab er også blevet rapporteret.
English: Study in children/adolescents aged 1 - 18 years with de novo ALL Efficacy and safety of Spectrila was compared to a native E. coli-asparaginase (reference medicinal product) in a randomised double-blinded clinical trial (study MC-ASP.5/ALL; based on ALL treatment protocol DCOG ALL10) in 199 children/adolescents aged 1 - 18 years with de novo ALL.
Danish: Studie hos børn/unge i alderen 1 - 18 år med de novo ALL Spectrilas virkning og sikkerhed blev sammenlignet med en naturligt forekommende E. coli-asparaginase (referencelægemiddel) i et randomiseret, dobbeltblindet klinisk studie (studie MC-ASP.5/ALL, baseret på ALL behandlingsprotokol DCOG ALL10) med 199 børn/unge i alderen 1 - 18 år med de novo ALL.
English: • Pre-existing known coagulopathy (e.g. haemophilia).
Danish: • Eksisterende, kendt koagulopati (f.eks. hæmofili).
English: No dose adjustment is necessary in patients with mild to moderate hepatic impairment.
Danish: Ingen dosisjustering er nødvendig hos patienter med let til moderat nedsat leverfunktion.
English: • high blood levels of amylase and lipase
Danish: • højt niveau af amylase og lipase i blodet
English: • Medicines which may have a negative effect on liver function since these negative effects may be worsened by concomitant treatment with asparaginase.
Danish: • Lægemidler, som kan have en negativ virkning på leverfunktionen, da disse negative virkninger kan forværres af samtidig behandling med asparaginase.
English: Clinical symptoms include abdominal pain, nausea, vomiting and anorexia.
Danish: Kliniske symptomer omfatter abdominalsmerter, kvalme, opkastning og anoreksi.
English: The reconstituted solution is stable for 2 days when stored at 2 °C - 8 °C.
Danish: Den rekonstituerede opløsning er stabil i 2 dage ved opbevaring ved 2 °C - 8 °C.
English: Coagulation disorders
Danish: Koagulationsforstyrrelser
English: • cholestasis (blocked bile flow from the liver)
Danish: • kolestase (blokeret galdeflow fra leveren)
English: Name and address of the manufacturer(s) responsible for batch release medac Gesellschaft für klinische Spezialpräparate mbH Theaterstr.
Danish: Navn og adresse på den fremstiller, der er ansvarlig for batchfrigivelse medac Gesellschaft für klinische Spezialpräparate mbH Theaterstr.
English: EU/1/15/1072/002 (5 vials)
Danish: EU/1/15/1072/002 (5 hætteglas)
English: • Vincristine (used to treat certain types of cancer) since the simultaneous use of vincristine and asparaginase may increase the risk of certain side effects.
Danish: • Vincristin (anvendes til at behandle visse former for kræft), da anvendelse af vincristin sammen med asparaginase kan øge risikoen for visse bivirkninger.
English: The diluted solution of asparaginase may be infused over 0.5 to 2 hours.
Danish: Den fortyndede opløsning med asparaginase kan infunderes i løbet af 0,5 til 2 timer.
English: Vincristine
Danish: Vincristin
English: Hyperammonaemia has been reported uncommonly in patients treated with asparaginase-containing therapy protocols, especially if patients suffer additionally from hepatic impairment.
Danish: Der er ikke hyppigt blevet rapporteret hyperammonæmi hos patienter i behandling med protokoller indeholdende asparaginase, især hvis patienterne også lider af nedsat leverfunktion.
English: Hyperammonaemia
Danish: Hyperammonæmi
English: Sinus vein thrombosis can occur.
Danish: Der kan opstå sinusvenetrombose.
English: In clinical trials with asparaginase, trough asparaginase serum activity levels greater than 100 U/l were achieved in the majority of patients which nearly always correlated with a complete depletion of asparagine in serum and cerebrospinal fluid (CSF).
Danish: I kliniske studier med asparaginase blev det minimale aktivitetsniveau i serum over 100 E/l opnået hos de fleste patienter, hvilket næsten altid korrelerede med en fuldstændig tømning af asparagin i serum og cerebrospinalvæsken (CSF).
English: Due to the inhibition of protein synthesis (decreased synthesis of factors II, V, VII, VIII, and IX, proteins C and S, antithrombin III [AT III]) caused by asparaginase, coagulation disorders can occur which can manifest either as thrombosis, disseminated intravascular coagulation (DIC), or bleeding.
Danish: På grund af hæmningen af proteinsyntesen (nedsat syntese af faktor II, V, VII, VIII og IX, protein C og S, antitrombin III [AT III]) forårsaget af asparaginase, kan der opstå koagulationsforstyrrelser, som kan vise sig enten som trombose, dissemineret intravaskulær koagulation (DIC) eller blødning.
English: What you need to know before you are given Spectrila
Danish: Det skal du vide, før du begynder at få administreret Spectrila
English: Median (range)
Danish: Median (inteval)
English: As a result of impaired protein synthesis, the serum protein level (especially albumin) decreases very commonly in patients treated with asparaginase.
Danish: Som følge af en hæmmet proteinsyntese falder niveauet af serumprotein (især albumin) meget hyppigt hos patienter i behandling med asparaginase.
English: In case of occurrence of allergic symptoms, administration of Spectrila should be discontinued immediately (see section 4.4).
Danish: Hvis der opstår allergiske symptomer, skal administrationen af Spectrila straks seponeres (se pkt.
English: Treatment with asparaginase should be interrupted if patients develop severe hepatic impairment (bilirubin > 3 times the upper limit of normal [ULN]; transaminases > 10 times ULN), severe hypertriglyceridaemia, hyperglycaemia or coagulation disorder (e.g. sinus vein thrombosis, severe bleeding).
Danish: Behandlingen med asparaginase skal afbrydes, hvis patienterne udvikler svært nedsat leverfunktion (bilirubin > 3 gange den øvre normalgrænse [ULN], transaminaser > 10 gange ULN), svær hypertriglyceridæmi, hyperglykæmi eller koagulationsforstyrrelse (f.eks. sinusvenetrombose, svær blødning).
English: • anaphylaxis,
Danish: • anafylaksi,
English: 6,700 U/m² BSA,
Danish: 6.700 E/m² BSA,
English: 60,165 (38,627 - 80,764) U*h/l
Danish: 60.165 (38.627 - 80.764) E*t/l
English: Trough serum activity levels were measured in 12 infants (age from birth to 1 year) with de novo ALL (study MC-ASP.6/INF).
Danish: De minimale aktivitetsniveauer i serum blev målt hos 12 spædbørn (i alderen fra fødsel til 1 år) med de novo ALL (studie MC-ASP.6/INF).
English: • if you are allergic to asparaginase or to any of the other ingredients of this medicine (listed in section 6),
Danish: • hvis du er allergisk over for asparaginase eller over for et af de øvrige indholdsstoffer i Spectrila
English: • if you have a blood clotting disorder (such as haemophilia),
Danish: • hvis du har en blodstørkningssygdom (såsom hæmofili).
English: Hepatic parameters should be monitored when potentially hepatotoxic medicinal products are given concomitantly with asparaginase (see sections 4.4 and 4.8).
Danish: Leverparametrene bør overvåges, når muligt hepatotoksiske lægemidler gives samtidigt med asparaginase (se pkt.
English: Measurement of the asparaginase activity level in serum or plasma may be undertaken in order to rule out accelerated reduction of asparaginase activity.
Danish: Måling af asparaginases aktivitetsniveau i serum eller plasma kan udføres for at udelukke accelereret reduktion af asparaginaseaktiviteten.
English: Chemical and physical in-use stability has been demonstrated for 2 days at 2 °C - 8 °C.
Danish: Rekonstitueret og fortyndet opløsning Der er blevet påvist kemisk og fysisk stabilitet under brug i 2 dage ved 2 °C - 8 °C.
English: Immediately after the end of infusion of asparaginase, serum levels of glutamine declined by a maximum of 50 % from pre-dose levels of about 400 µM but rapidly returned to normal values within a few hours.
Danish: 50 % fra niveauer før dosering på ca. 400 µM, men de vendte hurtigt tilbage til de normale værdier i løbet af få timer.
English: 7,500 U/m² BSA,
Danish: 7.500 E/m² BSA,
English: Renal impairment No dose adjustment is necessary in patients with renal impairment.
Danish: Nedsat nyrefunktion Ingen dosisjustering er nødvendig hos patienter med nedsat nyrefunktion.
English: • loss of appetite or weight loss
Danish: • appetitløshed eller vægttab
English: Measurement of the asparaginase activity level in serum or plasma may be undertaken in order to rule out accelerated elimination of asparaginase activity.
Danish: Måling af asparaginases aktivitetsniveau i serum eller plasma kan udføres for at udelukke accelereret elimination af asparaginaseaktiviteten.
English: Haemorrhagic pancreatitis, necrotising pancreatitis, parotitis Very rare
Danish: Blødende pankreatitis, nekrotiserende pankreatitis, parotitis Meget sjælden
English: Decreased protein synthesis can predominantly lead to liver impairment, acute pancreatitis, decreased insulin production with hyperglycaemia, decreased production of clotting factors (especially fibrinogen and antithrombin III) leading to coagulation disorders (thrombosis, bleeding), and decreased production of lipoproteins resulting in hypertriglyceridaemia.
Danish: En nedsat proteinsyntese kan primært føre til nedsat leverfunktion, akut pankreatitis, nedsat insulinproduktion med hyperglykæmi, nedsat produktion af størkningsfaktorer (især fibrinogen og antitrombin III), der fører til koagulationsforstyrrelser (trombose, blødning), og nedsat produktion af lipoproteiner, hvilket fører til hypertriglyceridæmi.
English: The recommended intravenous dose of asparaginase is 5,000 units per square metre (U/m²) body surface area (BSA) given every third day.
Danish: Den anbefalede intravenøse dosis af asparaginase er 5.000 enheder pr. kvadratmeter (E/m²) legemsoverfladeareal (BSA), der gives hver tredje dag.
English: What Spectrila contains
Danish: Spectrila indeholder:
English: • seizures, severe impairment of consciousness including coma, and stroke
Danish: • krampeanfald, svært nedsat bevidsthed, herunder koma og slagtilfælde
English: Hypersensitivity including bronchospasm Rare
Danish: Almindelig Overfølsomhed, herunder bronkospasme
English: Hyperglycaemia and hypoglycaemia
Danish: Hyperglykæmi og hypoglykæmi
English: For intravenous use ONLY.
Danish: KUN til intravenøs anvendelse.
English: For intravenous use only.
Danish: Kun til intravenøs anvendelse.
English: Allergy and anaphylaxis
Danish: Allergi og anafylaksi
English: Most frequently (very common) observed side effects of Spectrila include hypersensitivity reactions, hyperglycaemia, hypoalbuminaemia, nausea, vomiting, diarrhoea, abdominal pain, oedema, fatigue, and change in laboratory parameters (e.g. transaminases, bilirubin, blood lipids, coagulation parameters).
Danish: Hyppigst (meget almindelig) observerede bivirkninger af Spectrila omfatter overfølsomhedsreaktioner, hyperglykæmi, hypoalbuminæmi, kvalme, opkastning, diarré, abdominalsmerter, ødem, træthed og ændringer i laboratorieparametre (f.eks. transaminaser, bilirubin, lipider i blodet, koagulationsparametre).
English: • severe inflammation of the pancreas (acute pancreatitis),
Danish: • svær betændelse i bugspytkirtlen (akut pankreatitis),
English: Rare Diabetic ketoacidosis
Danish: Diabetisk ketoacidose