FrancophonIA/ELRC3.0 huggingface dataset:
English: Pulmonary embolism, Pneumothorax, Haemoptysis, Asthma, Dyspnoea exertional
Croatian: Poremećaji dišnog sustava, prsišta i sredoprsja dispneja, epistaksa, kašalj, rinoreja plućna embolija, pneumotoraks, hemoptiza, astma, astma, dispneja pri naporu
English: Oxaliplatin on Day 1, every 2 weeks
Croatian: prvog dana, prije FOLFOX-4 protokola, svaka 2 tjedna
English: -2nd appearance -3rd appearance -4th appearance
Croatian: • Stupanj 3 -1. pojavljivanje Prekinuti dok se ne svede na stupanj -2. pojavljivanje -3. pojavljivanje
English: Hypokalaemia, Appetite disorder, Malnutrition, Hypertriglyceridaemia,
Croatian: Poremećaji metabolizma i prehrane smanjen apetit hipokalijemija, hiponatrijemija, hipomagnezijemija, hipokalcijemija, hiperglikemija
English: NAME OF THE MEDICINAL PRODUCT Capecitabine SUN 150 mg film-coated tablets capecitabine
Croatian: Kapecitabin SUN 150 mg filmom obložene tablete kapecitabin
English: - ECF: epirubicin (50 mg/m2 as a bolus on day 1 every 3 weeks), cisplatin (60 mg/m2 as a two hour infusion on day 1 every 3 weeks) and 5-FU (200 mg/m2 daily given by continuous infusion via a central line).
Croatian: - ECF: epirubicin (50 mg/m2 kao bolus 1. dan, svaka 3 tjedna), cisplatin (60 mg/m2 kao dvosatna infuzija 1. dan, svaka 3 tjedna) i 5-FU (200 mg/m2 dnevno u obliku kontinuirane infuzije putem centralnog venskog katetera) - ECX: epirubicin (50 mg/m2 kao bolus 1. dan, svaka 3 tjedna), cisplatin (60 mg/m2 kao dvosatna infuzija 1. dan, svaka 3 tjedna) i kapecitabin (625 mg/m2 dvaput dnevno bez pauze) - EOF: epirubicin (50 mg/m2 kao bolus 1. dan, svaka 3 tjedna), oksaliplatin (130 mg/m2 kao dvosatna infuzija 1. dan, svaka 3 tjedna) i 5-FU (200 mg/m2 dnevno u obliku kontinuirane infuzije putem centralnog venskog katetera) - EOX: epirubicin (50 mg/m2 kao bolus 1. dan, svaka 3 tjedna), oksaliplatin (130 mg/m2 kao dvosatna infuzija 1. dan, svaka 3 tjedna) i kapecitabin (625 mg/m2 dvaput dnevno bez pauze)
English: skin loss, skin inflammation, nail disorder
Croatian: hiperpigmentacija kože, makularni osip, ljuštenje kože,
English: 53% to 60% of all-grades HFS was observed in capecitabine monotherapy trials (comprising studies in adjuvant therapy in colon cancer, treatment of metastatic colorectal cancer, and treatment of breast cancer) and a frequency of 63% was observed in the capecitabine/docetaxel arm for the treatment of metastatic breast cancer.
Croatian: Sindrom šaka-stopalo (vidjeti dio 4.4) Za dozu kapecitabina od 1250 mg/m2 koja je primijenjena dvaput dnevno od 1. do 14. dana ciklusa svaka 3 tjedna učestalost od 53% do 60% svih stupnjeva sindroma šaka-stopalo uočena je u ispitivanjima monoterapije kapecitabinom (ispitivanjima adjuvantne terapije u bolesnika s karcinomom debelog crijeva, terapije bolesnika s metastatskim kolorektalnim karcinomom i terapije karcinoma dojke), a učestalost od 63% uočena je u skupini liječenoj kombinacijom kapecitabina i docetaksela zbog metastatskog karcinoma dojke.
English: Oxaliplatin on Day 1, every 3 weeks Capecitabine oral twice daily for 2 weeks (followed by 1 week offtreatment)
Croatian: XELOX ili XELOX i bevacizumab oksaliplatin 130 mg/m2 i.v./2 sata oksaliplatin prvog dana, svaka 3 tjedna kapecitabin oralno dvaput dnevno tijekom 2 tjedna (nakon čega slijedi 1 tjedan pauze)
English: per day using either a continuous schedule or given daily Monday through Friday during a 6-week course of radiotherapy.
Croatian: dnevno, a u kombinaciji s radioterapijom kod karcinoma debelog crijeva MTD kapecitabina iznosi 2000 mg/m2 dnevno pri kontinuiranoj (svakodnevnoj) primjeni ili pri uzimanju tijekom 5 dana od ponedjeljka do petka, uz radioterapiju u trajanju od 6 tjedana.
English: Capecitabine SUN 150 mg film-coated tablets are light peach coloured, oval, biconvex, 11.5 mm x
Croatian: Kapecitabin SUN 150 mg filmom obložene tablete su ovalne, bikonveksne tablete, svijetle boje breskve, veličine 11,5 mm x 5,7 mm, s oznakom ´150´ s jedne strane i bez oznake s druge strane.
English: ANNEX II
Croatian: • Stupanj 2
English: Ventricular fibrillation (rare), QT prolongation (rare), Torsade de pointes (rare), Bradycardia (rare), Vasospasm (rare)
Croatian: Srčani poremećaji nestabilna angina, angina pektoris, ishemija miokarda, fibrilacija atrija, aritmija, tahikardija, sinusna tahikardija, palpitacije fibrilacija ventrikula (rijetko), produljenje QTintervala (rijetko), Torsade de pointes (rijetko), bradikardija (rijetko), vazospazam (rijetko)
English: Dose modifications applied should be applied for the precipitating adverse event as necessary (see section 4.2).
Croatian: Ukoliko je potrebno, dozu treba prilagoditi ovisno o nuspojavi (vidjeti dio
English: Lipoma
Croatian: OBLIK
English: 5-fluorouracil IV bolus/infusion, each on Days 1 and 2, every 2 weeks
Croatian: FOLFOX-4 ili FOLFOX-4 i bevacizumab oksaliplatin 85 mg/m2 i.v./2 sata oksaliplatin prvog dana, svaka 2 tjedna leukovorin prvog i drugog dana, svaka
English: Types and Mechanisms of Resistance
Croatian: Vrste i mehanizam otpornosti
English: The bioavailability of the veterinary medicinal product is at least 60%.
Croatian: Bioraspoloživost veterinarsko medicinskog proizvoda iznosi najmanje 60%.
English: Tell your veterinarian about all medicines that you intend to give the animal.
Croatian: Obavijestite vašeg veterinara o svim proizvodima koje namjeravate dati životinji.
English: ATCvet code: QJ01MA97
Croatian: ATCvet kod: QJ01MA97
English: Tell your veterinarian if your animal has impaired kidney function.
Croatian: Obavijestite svog veterinara ako vaša životinja ima oštećenu funkciju bubrega.
English: Approximately 40% of the administered product is excreted unchanged via the kidneys.
Croatian: Približno 40% primijenjenog proizvoda izlučeno je nepromijenjeno preko bubrega.
English: Administer directly into the mouth.
Croatian: Aplicirati izravno u usta.
English: Veraflox oral suspension is supplied in two different presentations:
Croatian: Veraflox peroralna suspenzija isporučuje se u dva različita pakovanja:
English: Antibacterial Spectrum
Croatian: Antibakterijski spektar
English: The following pack sizes are available:
Croatian: Sljedeće veličine pakovanja su dostupne:
English: However in the clinical studies feeding did not reveal any impact on the treatment effect.
Croatian: Međutim, klinička ispitivanja nisu otkrila ikakav utjecaj na učinak liječenja.
English: Pradofloxacin may increase sensitivity of the skin to sunlight.
Croatian: Pradofloksacin može pojačati osjetljivost kože na sunčevo svjetlo.
English: When the dose requires a half tablet to be used the remaining portion should be given at the next administration.
Croatian: Kada doza iznosi pola tablete, preostali dio treba dati kod sljedeće primjene.
English: The bacteria were isolated between 2001 and 2007 from clinical cases in Belgium, France, Germany, Hungary, Italy, Poland, Sweden and UK.
Croatian: Bakterije su izolirane između 2001. i 2007. kod kliničkih slučajeva u Belgiji, Francuskoj, Njemačkoj, Mađarskoj, Italiji, Poljskoj, Švedskoj i Velikoj Britaniji.
English: The bacteria were isolated between 2001 and 2007 from clinical cases in Belgium, France, Germany, Hungary, Poland, Sweden and UK.
Croatian: Bakterije su izolirane između 2001. i 2007. kod kliničkih slučajeva u Belgiji, Francuskoj, Njemačkoj, Mađarskoj, Poljskoj, Švedskoj i Velikoj Britaniji.
English: During treatment, animals should therefore not be exposed to excessive sunlight.
Croatian: Stoga, tijekom liječenja, životinje ne bi trebalo pretjerano izlagati suncu.
English: Duration of treatment (days)
Croatian: Trajanje liječenja (u danima)
English: Pradofloxacin
Croatian: Pradofloksacin
English: Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Croatian: Fluorokinoloni bi trebali biti rezervirani za liječenje kliničkih stanja koja slabo reagiraju, ili se očekuje da slabo reagiraju, na druge skupine antimikrobnih proizvoda.
English: Shake well before use.
Croatian: Dobro protresite prije upotrebe.
English: The bioavailability of the tablet is at least 70%.
Croatian: Bioraspoloživost tableta iznosi najmanje 70%.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each ml contains:
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Svaki ml sadrži:
English: This veterinary medicinal product should only be used in severe cases of periodontal disease.
Croatian: Ovaj veterinarsko medicinski proizvod trebalo bi primjenjivati samo u teškim slučajevima periodontalnih bolesti.
English: Whenever possible, the veterinary medicinal product should only be used based on susceptibility testing.
Croatian: Kad god je moguće, veterinarsko medicinski proizvod treba koristiti na temelju testa osjetljivosti.
English: Mechanical cleaning of teeth and removal of plaque and calculus or extraction of teeth are prerequisites for a persistent therapeutic effect.
Croatian: Mehaničko čišćenje zuba i uklanjanje plaka i kamenca ili vađenje zuba su preduvjeti za dugotrajan terapijski učinak.
English: SPECIAL WARNING(S), IF NECESSARY Avoid introduction of contamination during use.
Croatian: POSEBNO(A) UPOZORENJE(A), UKOLIKO JE POTREBNO Izbjegavati kontaminaciju tijekom primjene.
English: Lot {number}
Croatian: Lot: {broj}
English: In vitro plasma protein binding is low (35%).
Croatian: In vitro vezanje na proteine plazme je nisko (35%).
English: The rapidity and extent of bacterial killing are directly proportional to the drug concentration.
Croatian: Brzina i opseg ubijanja bakterija izravno su proporcionalni koncentraciji lijeka.
English: Pyoderma occurs mostly secondary to an underlying disease, thus, it is advisable to determine the underlying cause and to treat the animal accordingly.
Croatian: Pioderma se javlja najčešće sekundarno na osnovnu bolest, stoga je preporučljivo otkriti osnovni uzrok i sukladno tome liječiti životinju.
English: In order to avoid cross-contamination, the same syringe should not be used for different animals.
Croatian: Da bi se izbjegla unakrsna kontaminacija, ista šprica ne bi se trebala koristiti kod različitih životinja.
English: Veraflox should only be used in severe cases of periodontal disease.
Croatian: Veraflox bi se trebao primjenjivati samo u teškim slučajevima periodontalnih bolesti.
English: Dose of oral suspension to be given (ml)
Croatian: Doza peroralne suspenzije koja se mora dati (ml)
English: Pradofloxacin concentrations in skin homogenates of dogs exceed those in serum by up to seven times.
Croatian: Koncentracije pradofloksacina u homogenatima kože premašuje onu u serumu do sedam puta.
English: In case of contact with the skin, rinse off with water.
Croatian: U slučaju kontakta s kožom, isperite vodom.
English: In vitro plasma protein binding is low (30%).
Croatian: In vitro vezanje na proteine plazme je slabo (30%).
English: Thus, one syringe should only be used for one animal.
Croatian: Stoga, jedna šprica bi se trebala koristiti samo za jednu životinju.
English: Draw out the equivalent dosage into the syringe.
Croatian: Navući odgovarajuću dozu u špricu.
English: The primary mode of action of the fluoroquinolones involves interaction with enzymes essential for major DNA functions such as replication, transcription and recombination.
Croatian: Primarni način djelovanja fluorokinolona uključuje interakcije s enzimima esencijalnim za važne funkcije DNA kao što su replikacija, transkripcija i rekombinacija.
English: All mechanisms lead to a reduced susceptibility of the bacteria to fluoroquinolones.
Croatian: Svi mehanizmi dovode do smanjene osjetljivosti bakterija na fluorokinolone.
English: The duration of the treatment depends on the nature and severity of the infection and on the response to treatment.
Croatian: Trajanje liječenja ovisi o prirodi i jačini infekcije i o odgovoru na liječenje.
English: The medication should be administered for as long as advised by your veterinarian.
Croatian: Proizvod je potrebno davati onoliko dugo koliko je preporučio vaš veterinar.
English: - 7 tablets - 21 tablets - 70 tablets - 140 tablets
Croatian: - 7 tableta - 21 tableta - 70 tableta - 140 tableta
English: One syringe should therefore only be used for one animal.
Croatian: Jedna šprica bi se stoga trebala koristiti samo za jednu životinju.
English: Do not eat, drink or smoke while handling the veterinary medicinal product.
Croatian: Zabranjeno je jesti, piti ili pušiti dok se rukuje s veterinarsko medicinskim proizvodom.
English: People with known hypersensitivity to quinolones should avoid any contact with the veterinary medicinal product.
Croatian: Osobe preosjetljive na kinolone trebaju izbjegavati kontakt s veterinarsko-medicinskim proizvodom.
English: In case of accidental contact with the eyes, wash immediately with water.
Croatian: U slučaju nehotičnog kontakta s očima, isperite odmah vodom
English: In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Croatian: Zbog nedostatka studija kompatibilnosti, ovaj veterinarsko-medicinski proizvod ne smije se miješati s drugim veterinarsko-medicinskim proizvodima.
English: 2 mg For the full list of excipients, see section 6.1.
Croatian: 2 mg Potpuni popis pomoćnih tvari vidi u odjeljku 6,1.
English: Bacterial species
Croatian: Vrste bakterija
English: For the majority of breeds, pradofloxacin-containing veterinary medicinal products must not be used in dogs of less than 12 months of age and in giant breeds less than 18 months.
Croatian: Kod većine pasmina, veterinarsko medicinski proizvodi koji sadrže pradofloksacin ne smiju se primjenjivati kod pasa mlađih od 12 mjeseci te kod velikih pasmina mlađih od 18 mjeseci.
English: The combination of fluoroquinolones with theophylline could increase the plasma levels of theophylline by altering its metabolism and thus should be avoided.
Croatian: Kombinacija fluorokinolona s teofilinom može pojačati količine teofilina u plazmi mijenjanjem metabolizma i stoga se treba izbjegavati.
English: Cross-resistance within the fluoroquinolone class of antimicrobials is common.
Croatian: Unakrsna otpornost u grupi fluorokinolonskih antimikrobnih tvari je česta.
English: Official and local antimicrobial policies should be taken into account when the veterinary medicinal product is used.
Croatian: Službeni i lokalni antimikrobni propisi trebali bi se uzeti u obzir kada se koristi veterinarsko medicinski proizvod.
English: The period of growth depends on the breed.
Croatian: Razdoblje rasta ovisi o pasmini.
English: After administration, the syringe should be cleaned with tap water and stored in the carton box together with the veterinary medicinal product.
Croatian: Nakon primjene, špricu je potrebno oprati pod vodom iz pipe i pohraniti u kartonskoj kutiji zajedno sa veterinarsko medicinskim proizvodom.
English: Vomiting and soft faeces may be symptoms of overdose.
Croatian: Povraćanje i mekan izmet mogu biti simptomi predoziranja.
English: Infections of the skin: Superficial pyoderma Deep pyoderma Wound infections Acute infections of the urinary tract Severe infections of the gingiva and periodontal tissues
Croatian: Infekcije kože: Površinska pioderma Duboka pioderma Infekcije rana Akutne infekcije urinarnog trakta Teške infekcije gingive i periodontalnih tkiva
English: Number of 15 mg tablets
Croatian: Broj tableta od 15 mg
English: Although pradofloxacin has in-vitro activity against a wide range of Gram-positive and Gramnegative organisms, including anaerobic bacteria, this veterinary medicinal product should only be used for the approved indications (see section 4.2) and in accordance with the prudent use recommendations in section 4.5 of this SPC.
Croatian: Iako pradofloksacin ima in vitro djelovanje protiv širokog spektra Gram-pozitivnih i Gram-negativnih organizama, uključujući anaerobne bakterije, ovaj veterinarsko medicinski proizvod trebao bi se primjenjivati samo kod odobrenih indikacija (vidi odjeljak 4.2) i u skladu s preporukama za razboritu primjenu u odjeljku 4.5 ovog SPC-ja.
English: To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
Croatian: Da bi osigurali ispravno doziranje, tjelesnu masu treba što točnije odrediti da bi se izbjeglo subdoziranje.
English: Pharmacotherapeutic group: Antibacterials for systemic use, fluoroquinolones.
Croatian: Farmakoterapijska grupa: Antibakterijske tvari za sustavnu primjenu, fluorokinoloni.
English: Whenever possible, Veraflox should only be used based on susceptibility testing.
Croatian: Kad god je moguće, Veraflox bi se trebao koristiti samo na temelju testa osjetljivosti.
English: Pregnancy, lactation, Fertility:
Croatian: Graviditet, laktacija, plodnost:
English: Fluoroquinolones are known to cross the placenta and to be distributed into milk.
Croatian: Za fluorokinolone je poznato da prolaze placentu i izlučuju se u mlijeko.
English: The combined use of fluoroquinolones with digoxin should also be avoided because of potentially increased oral bioavailability of digoxin.
Croatian: Kombiniranu primjenu fluorokinolona s digoksinom također treba izbjegavati zbog potencijalno povećane peroralne bioraspoloživosti digoksina.
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Veterinary medicinal product subject to prescription.
Croatian: UVJETI ILI OGRANIČENJA U POGLEDU OPSKRBE I PRIMJENE Veterinarsko-medicinski proizvod koji se izdaje na recept.
English: TARGET SPECIES Dogs and cats
Croatian: CILJNE VRSTE ŽIVOTINJA Psi i mačke
English: The primary targets for pradofloxacin are the bacterial DNA gyrase and topoisomerase IV enzymes.
Croatian: Primarni ciljevi za pradofloksacin su bakterijska DNA giraza i enzimi topoizomeraze IV.
English: For most infections the following treatment courses will be sufficient:
Croatian: Za većinu infekcija navedeni način liječenja biti će dostatan.
English: In case of gingivitis and periodontitis, the veterinary medicinal product should only be used as an adjunct to mechanical or surgical periodontal therapy.
Croatian: U slučaju gingivitisa i periodontitisa, veterinarskomedicinski proizvod trebao bi se primjenjivati samo kao dopuna mehaničkoj ili kirurškoj periodontalnoj terapiji.
English: The combined use of Veraflox with theophylline (used with chronic respiratory conditions) or digoxin (used with congestive heart failure) should also be avoided because of potentially higher blood levels which could increase the effects of these drugs.
Croatian: Kombinirana primjena Verafloxa s teofilinom (koji se koristi kod kroničnih respiratornih stanja) ili digoksinom (koji se koristi kod kongestivnog zatajenja srca) također se treba izbjegavati zbog potencijalno više razine u krvi što može pojačati učinak tih veterinarsko medicinskih proizvoda.
English: Tablets.
Croatian: Tablete
English: In case of gingivitis and periodontitis, Veraflox should only be used as an adjunct to mechanical or surgical periodontal therapy.
Croatian: U slučaju gingivitisa i periodontitisa, Veraflox bi se trebao primjenjivati samo kao dopuna mehaničkoj ili kirurškoj periodontalnoj terapiji.
English: To facilitate accurate dosing, the 15 ml bottle of Veraflox oral suspension is supplied together with a 3 ml oral dosing syringe (graduation: 0.1 to 2 ml).
Croatian: Da bi se omogućilo točno doziranje, bočica Veraflox peroralne suspenzije od 15 ml isporučuje se zajedno sa 3ml oralnom špricom za doziranje (graduacija: 0,1 do 2 ml).
English: After administration the syringe should be cleaned with tap water and stored with the bottle in the carton box.
Croatian: Nakon primjene špricu treba oprati vodom i spremiti s bočicom u kartonsku kutiju.
English: Pregnancy, lactation and Fertility:
Croatian: Graviditet, laktacija i plodnost:
English: The high volume of distribution (Vd) >2 l/kg bodyweight indicates good tissue penetration.
Croatian: Visoki volumen distribucije (Vd)>2 l/kg tjelesne mase indicira dobro prodiranje u tkiva.
English: The high volume of distribution (Vd) >4 l/kg body weight indicates good tissue penetration.
Croatian: Visok volumen raspodjele (Vd)>4 l/kg tjelesne mase ukazuje da je prodiranje u tkiva dobro.
English: The major elimination pathway in cats is glucuronidation.
Croatian: Glavni put eliminacije kod mačaka je glukuronidacija.
English: Concurrent administration with metal cations such as those contained in antacids or sucralfate made with magnesium hydroxide or aluminium hydroxide, or multivitamins containing iron or zinc, and dairy products containing calcium, has been reported to decrease the bioavailability of fluoroquinolones.
Croatian: Istodobna primjena s metalnim kationima kao što su oni koji se nalaze u antacidima ili sukralfatu napravljenom s magnezij hidroksidom ili aluminij hidroksidom, ili multivitaminima koji sadrže željezo ili cink, mliječnim proizvodima koji sadrže kalcij, rezultirassmanjenjem bioraspoloživosti fluorokinolona.
English: Ask your veterinarian for advice if no improvement of the clinical conditions is observed within 3 days after starting the treatment, although for superficial pyoderma this time should be increased to 7 days, and for deep pyoderma to 14 days.
Croatian: Pitajte svog veterinara za savjet ako se ne uočava poboljšanje kliničkog stanja u roku 3 dana od početka liječenja, iako kod površinske pioderme to vrijeme treba produžiti do 7 dana, a kod duboke pioderme do 14 dana.
English: MIC-Data
Croatian: MIC-Podaci
English: Long-term daily treatment has no impact on the pharmacokinetic profile, with an accumulation index of 1.1.
Croatian: Dugotrajna dnevna primjena nema utjecaj na farmakokinetički profil, uz akumulacijski indeks od 1,1.
English: Only those dogs for which periodontal treatment goals cannot be achieved by mechanical treatment alone should be treated with this veterinary medicinal product.
Croatian: Samo oni psi kod kojih se svrha periodontalnog liječenja ne može postići samo mehaničkim liječenjem trebali bi se liječiti s ovim veterinarsko medicinskim proizvodom.
English: ADVICE ON CORRECT ADMINISTRATION The oral suspension should be given by direct oral administration as shown below:
Croatian: Peroralna suspenzija daje se izravno u usta kako je prikazano ispod:
English: A linear relationship between pradofloxacin serum concentrations and the administered dose is observed in dogs within a tested dose range of 1 to 9 mg/kg body weight.
Croatian: Linearan odnos između koncentracije pardofloksacina u serumu i primijenjene doze uočena je kod pasa s testnom dozom u rasponu od 1 do 9 mg/kg tjelesne mase.
English: Excretion via kidneys is an important elimination route for pradofloxacin in dogs.
Croatian: Izlučivanje preko bubrega je važan put eliminacije za pradofloksacin kod pasa.
English: Interactions with other medicinal products and other forms of interaction: There are some medicines that you should not give to your animal during treatment because if given together they might cause serious adverse effects.
Croatian: Postoje proizvodi koji se ne bi trebali davati vašoj životinji tijekom liječenja zbog toga što ako se daju zajedno mogu dovesti do ozbiljnih štetnih učinaka.
English: For dogs over 15 kg, use 60 mg or 120 mg pradofloxacin tablets.
Croatian: Za pse preko 15 kg koristiti tablete od 60 mg ili 120 mg pradofloksacina.
English: Pradofloxacin induced eye malformations at foetal and maternal toxic doses in rats.
Croatian: Pradofloksacin je inducirao malformacije na očima u fetotoksičnoj i maternotoksičnoj dozi kod štakora.
English: Lactose monohydrate Cellulose, microcrystalline Povidone
Croatian: Laktoza monohidrat Mikrokristalična celuloza Povidon
English: Excipients: Preservative: Sorbic acid (E200)
Croatian: Pomoćne tvari: Konzervans: sorbinska kiselina (E200)
English: Reversible association between pradofloxacin and DNA gyrase or DNA topoisomerase IV in the target bacteria results in inhibition of these enzymes and rapid death of the bacterial cell.
Croatian: Reverzibilno povezivanje između pradofloksacina i DNA giraze ili DNA topoizomeraze IV kod ciljnih bakterija rezultira inhibicijom tih enzima i brzom smrću bakterijskih stanica.
English: Due to the graduation of the syringe the resulting dose range is 5 to 7.5 mg/kg bodyweight according to the following table:
Croatian: Uslijed graduacije šprice proizlazi raspon doza od 5 do 7,5 mg/kg tjelesne mase prema sljedećoj tablici: