FrancophonIA/ELRC3.0 huggingface dataset:
English: The cause for the high resistance rate can be found in the mechanisms governing the development of non-horizontal transferable resistance.
Estonian: Suure resistentsuse põhjus võib olla mehhanismides, mis reguleerivad mittehorisontaalse ülekanduva resistentsuse teket.
English: 92521 Neuilly sur Seine cedex France
Estonian: 92521 Neuilly sur Seine cedex Prantsusmaa
English: Resistance is caused by point mutations of 23S rDNA.
Estonian: Resistentsust põhjustavad 23S rDNA punktmutatsioonid.
English: 1ere avenue 2065 m L. I. D. 06516 Carros
Estonian: Prantsusmaa VIRBAC 1ere avenue 2065 m L. I. D. 06516 Carros
English: 200 AVENUE DE MAYENNE ZONE INDUSTRIELLE DES TOUCHES
Estonian: Prantsusmaa SOGEVAL 200 AVENUE DE MAYENNE ZONE INDUSTRIELLE DES TOUCHES
English: 66-400 Gorzów Wielkopolski Poland
Estonian: 66-400 Gorzów Wielkopolski Poola
English: Kalinovica, 10436 Rakov Potok Croatia
Estonian: Kalinovica, 10436 Rakov Potok Horvaatia
English: 28108 Alcobendas (Madrid) Spain
Estonian: 28108 Alcobendas (Madrid) Hispaania
English: S.C. PASTEUR -FILIALA FILIPESTI
Estonian: Rumeenia S.C. PASTEUR -FILIALA FILIPESTI
English: Rua da Liberdade, n° 77 2050-023 Aveiras de Baixo Portugal
Estonian: Rua da Liberdade, nr 77 2050-023 Aveiras de Baixo Portugal
English: 42010 Rio Saliceto (RE) Italy
Estonian: 42010 Rio Saliceto (RE) Itaalia
English: ANDRES PINTALUBA, S.A. Pol. Industrial Agro-Reus c/ Prudenci Bertrana 5.
Estonian: Hispaania ANDRES PINTALUBA, S.A. Pol. Industrial Agro-Reus c/ Prudenci Bertrana 5.
English: Pharmagal spol.
Estonian: Slovakkia Pharmagal spol.
English: 12030 Cavallermaggiore (CN) Italy
Estonian: 12030 Cavallermaggiore (CN) Itaalia
English: SUPER´S DIANA, S.L.
Estonian: Hispaania SUPER´S DIANA, S.L.
English: Sintofarm Via P. Togliatti, 5 Guastalla (RE) Italy
Estonian: Sintofarm Via P. Togliatti, 5 Guastalla (RE) Itaalia
English: ZONE D'ACTIVITES DU BOIS DE TEILLAY
Estonian: Prantsusmaa DELTAVIT ZONE D'ACTIVITES DU BOIS DE TEILLAY
English: Via Don Eugenio Servadei 16 47122 Forlì, Forlì-Cesena Italy
Estonian: Via Don Eugenio Servadei 16 47122 Forlì, Forlì-Cesena Itaalia
English: V. del Commercio 28/30 41012 Carpi (MO) Italy
Estonian: V. del Commercio 28/30 41012 Carpi (MO) Itaalia
English: LABORATORIOS CALIER, S.A. BARCELONÉS, 26.
Estonian: Hispaania LABORATORIOS CALIER, S.A. BARCELONÉS, 26.
English: These products are effective medicines for the treatment of several diseases such as respiratory disease and ileitis/porcine intestinal adenopathy (caused by Lawsonia intracellularis).
Estonian: Ravimid on efektiivsed ravimid mitme haiguse, näiteks hingamisteede haiguse ja ileiidi / sigade intestinaalse adenopaatia raviks (haigustekitaja Lawsonia intracellularis).
English: As macrolides are critically important antimicrobials for pigs, unnecessary exposure leading to further resistance in target animal pathogens would be a serious risk to animal health.
Estonian: Kuivõrd makroliidid on sigade jaoks kriitiliselt tähtsad antimikroobikumid, oleks ebavajalik kokkupuude, mis suurendab veelgi sihtliigi patogeenide resistentsust, suur risk loomatervisele.
English: To limit the selection pressure for bacteria unnecessary use should be avoided.
Estonian: Bakterite selektsioonisurve piiramiseks tuleb vältida ebavajalikku kasutamist.
English: Via A. Gramsci, 731-733 50019 Sesto Fiorentino (IT) Italy
Estonian: Via A. Gramsci, 731-733 50019 Sesto Fiorentino (IT) Itaalia
English: LABORATOIRES BIOVE 3 RUE DE LORRAINE 62510 ARQUES France
Estonian: Prantsusmaa LABORATOIRES BIOVE 3 RUE DE LORRAINE 62510 ARQUES
English: Av. Infante D. Henrique nº 333-H 3º piso Esc. 41 1800-282 Lisboa Portugal
Estonian: Av. Infante D. Henrique nº 333-H 3º piso Esc. 41 1800-282 Lissabon Portugal
English: Oral tylosin has had widespread use in pig farming in many EU Member States for decades to treat and prevent disease and before entry into force of Regulation (EC) No 1831/2003, as a growth promoter.
Estonian: Suukaudset tülosiini on Euroopa Liidu liikmesriikides kasutatud aastakümneid seakasvatuses haiguste raviks ja ennetamiseks ning enne määruse (EÜ) nr 1831/2003 jõustumist ka kasvustimulaatorina.
English: The CVMP was asked to conclude on whether the duration of treatment with veterinary medicinal products containing tylosin beyond three weeks is justified and whether these products are still effective against swine dysentery caused by B. hyodysenteriae.
Estonian: Veterinaarravimite komiteelt küsiti järeldust, kas ravi tülosiini sisaldavate veterinaarravimitega kauem kui kolm nädalat on põhjendatud ja kas need tooted on endiselt efektiivsed B. hyodysenteriae tekitatava sigade düsenteeria vastu.
English: Risk management or mitigation measures
Estonian: Riskijuhtimise või riskide vähendamise meetmed
English: Dzierżoniowska 21 58-260 Bielawa Poland
Estonian: Dzierżoniowska 21 58-260 Bielawa Poola
English: IRIS Mednarodna trgovina d.o.o.,
Estonian: Sloveenia IRIS Mednarodna trgovina d.o.o.,
English: Ipswich, Suffolk, IP7 6RD United Kingdom
Estonian: Ipswich, Suffolk, IP7 6RD Ühendkuningriik
English: D-61352 Bad Homburg Germany
Estonian: D-61352 Bad Homburg Saksamaa
English: Medical Intertrade d.o.o.
Estonian: Horvaatia Medical Intertrade d.o.o.
English: 18-421 Kownaty Poland
Estonian: 18-421 Kownaty Poola
English: Polígono Industrial El Segre parcela 409-410.
Estonian: Polígono Industrial El Segre krunt 409-410
English: Denmark ScanVet Animal Health A/S Kongevejen 66
Estonian: ScanVet Animal Health A/S Kongevejen 66
English: Torre Occidente Rua Galileu Galilei, n.º 2 Piso 7 fração A/D, 1500-392 Lisboa Portugal
Estonian: Torre Occidente Rua Galileu Galilei, nr 2 Piso 7 fração A/D, 1500-392 Lissabon Portugal
English: Therefore, on 30 October 2013, Sweden presented to the Agency a referral notification under Article 35 of Directive 2001/82/EC for veterinary medicinal products containing tylosin to be administered orally via feed or the drinking water to pigs.
Estonian: Sel põhjusel tegi Rootsi 30. oktoobril 2013 EMA-le direktiivi 2001/82/EÜ artikli 35 kohase esildise seoses tülosiini sisaldavate sigadele sööda või joogiveega manustatavate suukaudsete veterinaarravimitega.
English: It may be administered by oral or parenteral routes.
Estonian: Neid võib manustada suu kaudu või parenteraalselt.
English: 17170 Amer (Girona) Spain
Estonian: 17170 Amer (Girona)
English: The potential risk for resistance development is evident through the current resistance situation of B. hyodysenteriae.
Estonian: Resistentsuse tekke potentsiaalne risk ilmneb praegusest olukorrast seoses B. hyodysenteriae resistentsusega.
English: D-30625 Hannover Germany
Estonian: D-30625 Hannover Saksamaa
English: Priestley Road Basingstoke, RG24 9NL United Kingdom
Estonian: Priestley Road Basingstoke, RG24 9NL Ühendkuningriik
English: Lilly France S.A.S.
Estonian: Prantsusmaa Lilly France S.A.S.
English: As previously mentioned, most oral tylosin products were authorised in the EU Member States long time ago according to marketing authorisation requirements at that time.
Estonian: Nagu juba mainitud, anti enamiku suukaudsete tülosiinravimite müügiluba Euroopa Liidu liikmesriikides aastaid tagasi tollaste müügiloanõuete kohaselt.
English: Similarly, almost complete in vitro resistance was reported among 32 Brachyspira isolates from the Czech Republic (Sperling et al. (2011))
Estonian: Samuti teatati Tšehhi Vabariigist pärit 32 Brachyspira isolaadi peaaegu täielikust in vitro resistentsusest (Sperling et al. (2011))
English: The general acceptance of the fact that antimicrobial treatment needs always to be combined with appropriate management and sanitary measures on the farm, to prevent the further spread of any particular microbe and thus reduce the risk for new clinical cases, makes it difficult to defend a need for very long treatment periods.
Estonian: Üldiselt nõustutakse, et antimikroobset ravi tuleb alati kombineerida asjakohase töökorralduse ja sanitaarmeetmetega põllumajandusettevõttes, et takistada konkreetse mikroobi edasist levikut ja seega vähendada uute kliiniliste juhtumite riski, on keeruline kaitsta ravi väga pika kestuse vajadust.
English: Elanco Valquímica, S.A. Avda.
Estonian: Hispaania Elanco Valquímica, S.A. Avda.
English: Extended and vaguely defined treatment periods present a risk from resistance perspective and would not be justifiable from a scientific point of view taking into account disease epidemiology as well as current awareness regarding the need to always combine antibiotic use with appropriate sanitary measures.
Estonian: Pikad ja ebamäärased raviperioodid on resistentsuse seisukohast risk ning ei ole teaduslikult põhjendatud, arvestades haiguse epidemioloogiat ja ka praegust teadlikkust, et antibiootikumide kasutamisega peavad alati kaasnema ne asjakohased sanitaarmeetmed.
English: List of the names, pharmaceutical forms, strengths of the veterinary medicinal products, animal species, and marketing authorisation holders in the Member States
Estonian: Veterinaarravimite nimetuste, ravimvormide, tugevuste, loomaliikide ja müügiloa hoidjate loetelu liikmesriikides
English: 949 01 Nitra Slovakia
Estonian: 949 01 Nitra
English: Since for B. hyodysenteriae the rRNA operon exists in a single copy one single base mutation is sufficient to achieve macrolide resistant clones (Zuerner and Stanton (1994)
Estonian: Kuivõrd B. hyodysenteriae puhul on rRNA operon ühes eksemplaris, piisab ühestainsast aluspaari mutatsioonist, et tekiksid makroliididele resistentsed kloonid (Zuerner ja Stanton (1994)
English: 2600 Antwerp
Estonian: 2600 Antwerpen Belgia
English: The knowledge regarding antimicrobial resistance risks has increased over time, and there is also an increasing focus on accommodating dosing strategy to the double aim of administering antimicrobials as long as necessary to obtain sufficient treatment effect, but to avoid unnecessary exposure that would encourage resistance development.
Estonian: Antimikroobse resistentsuse riskide kohta on aja jooksul saadud üha rohkem teavet, samuti on hakatud üha rohkem keskenduma annustamisstrateegia kohandamisele kahetisele eesmärgile: kuidas manustada antimikroobikume nii kaua kui on piisava ravimõju saavutamiseks vaja, samas vältides ebavajalikku kokkupuudet, mis suurendab resistentsust.
English: Although a somewhat lower rate of resistance was noted in Swedish strains collected during 1990-2010, more than 75% of the isolates demonstrate a minimum inhibitory concentration (MIC) far above the proposed epidemiological cut-off value of >16 μg/ml (Pringle et al. (2012))
Estonian: Kuigi aastatel 1990-2010 Rootsis kogutud tüvedel täheldati mõnevõrra väiksemat resistentsust, oli isolaatidest üle 75% korral ravimi minimaalne inhibeeriv kontsentratsioon (MIC) palju suurem kui kavandatud epidemioloogiline piirväärtus >16 μg/ml (Pringle et al. (2012))
English: For similar reasons recommendations to reduce the initial dose for an extended treatment period are not acceptable.
Estonian: Sarnastel põhjustel ei ole vastuvõetavad soovitused vähendada algannust pikemale raviperioodile.
English: 43206 Reus (Tarragona) Spain
Estonian: 43206 Reus (Tarragona) Hispaania
English: Replace, where applicable, treatment recommendations which are extended beyond 3 weeks, or where no treatment duration recommendation is given, with the following statement: Treatment duration should not exceed 3 weeks.
Estonian: Kus asjakohane, asendada üle 3 nädala kestva ravi soovitused järgmise lausega või, kui ravi kestuse soovitus puudub, lisada järgmine lause: „Ravi ei tohi kesta üle 3 nädala.”
English: Denmark Ceva Animal Health A/S Ladegårdsvej 2
Estonian: Ceva Animal Health A/S Ladegårdsvej 2
English: Germany aniMedica GmbH Im Südfeld 9
Estonian: Saksamaa aniMedica GmbH Im Südfeld 9
English: D-48308 Senden-Bösensell Germany
Estonian: D-48308 Senden-Bösensell Saksamaa
English: Wolfgang Schmälzlgasse 6 1020 Vienna
Estonian: Wolfgang Schmälzlgasse 6 1020 Viin
English: Germany bioptivet Tierarzneimittel GmbH & Co.
Estonian: Saksamaa bioptivet Tierarzneimittel GmbH & Co.
English: Tylosin and its phosphate and tartrate salts are used in food producing species for the treatment of conditions caused by sensitive organisms.
Estonian: Tülosiini ja selle fosfaat- ja tartraatsooli kasutatakse toiduloomaliikidel neile ainetele tundlike organismide tekitatud seisundite raviks.
English: The published scientific reports regarding the resistance situation for B. hyodysenteriae provide a discouraging picture, where tylosin resistance today is close to complete in many areas of the European Union.
Estonian: Avaldatud teaduslikud aruanded B. hyodysenteriae resistentsuse olukorrast annavad heidutava ülevaate, sest resistentsus tülosiini suhtes on praeguseks Euroopa Liidu paljudes piirkondades täielik.
English: LABORATORIOS HIPRA, S.A. Avda.
Estonian: Hispaania LABORATORIOS HIPRA, S.A. Avda.
English: DK-7100 Vejle
Estonian: DK-7100 Vejle Taani
English: 20884 Sulbiate (MB) Italy
Estonian: 20884 Sulbiate (MB) Itaalia
English: th international conference on colonic spirochaetal infections in animals and humans in the United Kingdom in September 2013, it was mentioned in a key note that: “tylosin has been rendered totally ineffective through widespread use for in-feed medication over the years” (Thomson (2013))
Estonian: Kooskõlas nende tähelepanekutega märgiti septembris 2013 Ühendkuningriigis toimunud kuuendas loomadel ja inimestel spiroheetide põhjustatava käärsoolepõletiku kuuenda rahvusvahelise konverentsi põhiteesis, et „tülosiin on muutunud täiesti ebaefektiivseks selle aastatepikkuse ulatusliku kasutamise tõttu ravimsöödas” (Thomson (2013))
English: Crida Pharm SRL str. Intrarea Vagonetului nr.2, bl.101, ap.47, parter, sector 6 Bucharest
Estonian: Rumeenia Crida Pharm SRL str. Intrarea Vagonetului nr 2, kv 101, krt 47, esimene korrus, sektor 6
English: Crockatt Road Lady Lane Industrial Estate, Hadleigh
Estonian: Rumeenia Anupco LTd. Crockatt Road Lady Lane Industrial Estate, Hadleigh
English: 1854 - 47020 Longiano (FC) Italy
Estonian: 1854-47020 Longiano (FC) Itaalia
English: Germany Lilly Deutschland GmbH Abt. Elanco Animal Health Werner-Reimers-Straße 2-4
Estonian: Saksamaa Lilly Deutschland GmbH Abt. Elanco Animal Health Werner-Reimers-Straße 2-4
English: In contrast, premix formulations authorised for the treatment and prevention of ileitis (caused by Lawsonia intracellularis) most often recommend treatment for not longer than up to three weeks.
Estonian: Seevastu ileiidi (haigustekitaja Lawsonia intracellularis) raviks ja ennetamiseks heakskiidetud ravimsööda eelsegusid soovitatakse enamasti kasutada ainult kuni kolmenädalaseks raviks.
English: DK-3480 Fredensborg Denmark
Estonian: DK-3480 Fredensborg Taani
English: Tylosin is not used in human medicine.
Estonian: Tülosiini ei kasutata inimtervishoius.
English: Risk assessment
Estonian: Riskide hindamine
English: SC Delos Impex 96 SRLStr Horia, Closca si Crisan, Otopeni judetul Ilfov
Estonian: Rumeenia SC Delos Impex 96 SRLStr Horia, Closca si Crisan, Otopeni Ilfovi maakond
English: The excessive use over time may explain the high proportion of resistance in B. hyodysenteriae strains, the cause for swine dysentery, reported from many European countries today.
Estonian: Liigne kasutamine pika aja jooksul võib põhjendada suurt resistentsust sigade düsenteeria tekitaja B. hyodysenteriae tüvedes, millest on praeguseks teatanud paljud Euroopa riigid.
English: GENERA d.d.
Estonian: Horvaatia GENERA d.d.
English: In addition, long-term exposure to low doses of tylosin is associated with an increase in the number of resistant Campylobacter coli and group medication with antibiotics is a risk factor for spread of methicillinresistant Staphylococcus aureus (MRSA) in pigs.
Estonian: Ka pikaajalist kokkupuudet väikseses koguses tülosiiniga seostatakse Campylobacter coli resistentsete bakterite sagenemisega ning kogu karja antibiootikumravi on metitsilliinresistentse Staphylococcus aureus'e (MRSA) sigadel levimise riskitegur.
English: In this situation it is not to be expected that scientifically well founded justifications for treatment durations can be obtained from the different marketing authorisation holders for different indications for pigs.
Estonian: Sellises olukorras ei saa eeldada, et müügiloa hoidjatelt saaks sigade eri näidustuste ravikestuse kohta teaduslikult hästi põhjendatud põhjendusi.
English: 20864 Agrate Brianza (MB) Italy
Estonian: 20864 Agrate Brianza (MB) Itaalia
English: Due to resistance development through recent decades, tylosin is however today not considered to provide sufficient efficacy against swine dysentery (B. hyodysenteriae), and the substance should thus not be used for this disease.
Estonian: Resistentsuse tekke tõttu viimastel aastakümnetel ei peeta tülosiini aga piisavalt efektiivseks sigade düsenteeria (B. hyodysenteriae) vastu ja seega ei tohi ainet selle haiguse raviks kasutada.
English: In a study of antimicrobial susceptibility of B. hyodysenteriae isolated from 21 Polish farms it was concluded that the lowest antimicrobial activity was demonstrated for tylosin and lincomycin, with inhibition of bacterial growth using concentrations >128 μg/ml and 32 μg/ml, respectively (Zmudzki et al. (2012)) 7.
Estonian: 21 Poola põllumajandusettevõttest isoleeritud B. hyodysenteriae antimikroobse tundlikkuse uuringus järeldati, et antimikroobne toime oli väikseim tülosiini ja linkomütsiini korral, kui bakterite kasvu inhibeerimisel kasutati vastavalt kontsentratsiooni >128 μg/ml ja 32 μg/ml (Zmudzki et al. (2012))
English: It is acknowledged that for certain holdings where susceptibility of B. hyodysenteriae to tylosin is still evident a removal of this indication would restrict the availability of treatment options.
Estonian: On teada, et teatud piirkondades, kus B. hyodysenteriae on veel tülosiini suhtes veel tundlik, piiraks näidustuse eemaldamine ravivõimaluste kättesaadavust.
English: 1000 Brussel
Estonian: 1000 Brüssel Belgia
English: Oral tylosin is regarded as an effective medicine against several diseases in pigs.
Estonian: Suukaudset tülosiini peetakse sigade mitme haiguse efektiivseks ravimiks.
English: It is acknowledged that many oral tylosin formulations for pigs currently available on the EU market have been authorised many years ago, according to posology justification standards regarded acceptable at that time and in the context of what was then regarded as acceptable strategies for the administration of antimicrobials.
Estonian: On teada, et paljude praegu sigadele manustatavate Europa Liidus turustatavate suukaudsete tülosiinipreparaatide möögiluba anti aastaid tagasi vastavalt tollal vastuvõetavaks peetud annustamise põhjendamise nõuetele, tollal vastuvõetavaks peetud antimikroobikumide manustamise strateegiate kontekstis.
English: However, effective alternatives are available (e.g. pleuromutilins) and, as there are very few susceptible outbreaks, the risk for inadequate treatment is deemed to outweigh the possible benefit of an additional treatment option in the unlikely event of confirmed susceptibility.
Estonian: Samas on olemas ka efektiivseid alternatiive (nt pleuromutiliinid) ja et ravimile tundlike bakterite puhanguid on väga vähe, on ebapiisava ravi risk kaalukam kui võimalik kasulikkus, mis kaasneb täiendava ravivõimalusega sellisel ebatõenäolisel juhul, kui kinnitatakse tundlikkus ravimi suhtes.
English: Although the resistance situation has not been investigated in every country where tylosin is used against swine dysentery, the awareness that tylosin resistance develops quickly and the bulk of in vitro data covering many field isolates from different areas provide sufficient information to conclude that it cannot be expected that the efficacy rate is sufficient to warrant an indication for treatment and prevention of this disease.
Estonian: Kuigi resistentsusolukorda ei ole uuritud igas riigis, kus sigade düsenteeriat ravitakse tülosiiniga, võib tülosiiniresistentsuse kiire tekke ja paljude eri piirkondadest saadud isolaatide in vitro andmete alusel järeldada, et ei saa eeldada, et efektiivsus oleks piisav, et näidustus selle haiguse raviks ja ennetamise oleks põhjendatud.
English: 47032 Bertinoro (FC) Italy
Estonian: 47032 Bertinoro (FC) Itaalia
English: It is however acknowledged that, regardless of the indication, for most oral tylosin formulations authorised for pigs at present the maximum recommended treatment duration is three weeks, indicating that this has in many cases been concluded to be a sufficient treatment period.
Estonian: Samas on teada, et olenemata näidustusest on sigade raviks heaks kiidetud suukaudsete tülosiinipreparaatide maksimaalne soovitatav ravikestus kolm nädalat, mis tähendab, et paljudel juhtudel on järeldatud, et see on piisav raviperiood.
English: Thus, to state that the administration of oral tylosin for pigs should not exceed three weeks is likely to assure sufficient treatment efficacy for currently authorised indications in pigs and this measure would also satisfy the requirement to avoid unnecessary exposure and thus reduce the risk for resistance development.
Estonian: Seega nõue, et suukaudset tülosiini ei tohi sigadele manustada üle kolme nädala, tagab tõenäoliselt ravi piisava efektiivsuse kasutamise korral sigadel praeguste heaks kiidetud näidustustel ning see meede rahuldaks ka nõude vältida ebavajalikku kokkupuudet ja sellega vähendada resistentsuse tekkeriski.
English: For products where any specific treatment duration shorter than 3 weeks is recommended this should be maintained in the product information.
Estonian: Toodetel, kus soovitatakse ravi kestust alla 3 nädala, tuleb see teave jätta ravimiteabes samaks.
English: the CVMP recommended variations of the marketing authorisations for veterinary medicinal products containing tylosin to be administered orally via feed or the drinking water to pigs (see Annex I) in order to amend the summaries of product characteristics, labelling and package leaflets in line with recommended changes in the product information as set out in Annex III.
Estonian: soovitas veterinaarravimite komitee muuta tülosiini sisaldavate sigadele sööda või joogiveega manustatavate suukaudsete veterinaarravimite (vt I lisa) müügilube, et muuta ravimi omaduste kokkuvõtteid, märgistust ja pakendi infolehti kooskõlas ravimiteabe soovitatud muudatustega, mis on esitatud III lisas.
English: To limit the administration of oral tylosin to pigs to a maximum of three weeks would reduce the risk for selection of resistance without hampering the effective use of these products against currently authorised and justifiable indications.
Estonian: Nõue, et sigadele tohib suukaudset tülosiini manustada ainult kuni kolm nädalat, vähendaks resistentsuse selektsiooni riski, piiramata samas toodete efektiivset kasutamist praegu heakskiidetud ja põhjendatud näidustustel.
English: Zavet JSC 5 Kiril i Metodii Str. Zavet
Estonian: Bulgaaria Zavet JSC Kiril i Metodii 5
English: Vet Rec, 168 Pringle, M., Landén, A., Ericsson Unnerstad, H., Molander, B. and Bengtsson N., 2012, Antimicrobial susceptibility of porcine Brachyspira hyodysenteriae and Brachyspira pilosicoli isolated in Sweden between 1990 and 2010- Acta Vet Scand,
Estonian: Pringle, M., Landén, A., Ericsson Unnerstad, H., Molander, B. and Bengtsson N., 2012, Antimicrobial susceptibility of porcine Brachyspira hyodysenteriae and Brachyspira pilosicoli isolated in Sweden between 1990 and 2010- Acta Vet Scand,
English: Delete, where applicable, any recommendation to reduce the dose after an initial treatment period with a higher dose.
Estonian: Kus asjakohane, kustutada soovitused, et annust vähendatakse pärast suurema annusega esialgset ravi.
English: A similar treatment strategy is recommended for tylosin premix formulation for the treatment of swine dysentery where it is mentioned that treatment can be continued ‘until the end of risk', ‘as long as necessary' or ‘until slaughter'.
Estonian: Sarnast ravistrateegiat soovitatakse tülosiini ravimsööda eelsegude jaoks sigade düsenteeria raviks, mispuhul mainitakse, et ravi tohib jätkata kuni ohu kadumiseni, nii kaua kui vaja või kuni tapmiseni.
English: 1000 Ljubljana Slovenia
Estonian: 1000 Ljubljana
English: Germany Kon-Pharma GmbH Senator-Bauer-Str. 34
Estonian: Saksamaa Kon-Pharma GmbH Senator-Bauer-Str. 34