FrancophonIA/ELRC3.0 huggingface dataset:
English: - The other ingredients are sodium phosphate monobasic, sodium phosphate dibasic, sodium chloride, polysorbate 80 and water for injections.
Slovenian: - Druge sestavine zdravila so natrijev hidrogenfosfat, natrijev dihidrogenfosfat, natrijev klorid, polisorbat 80 in voda za injekcije.
English: Do not use the pre-filled pen if the medicine is cloudy or discoloured or contains flakes or particles.
Slovenian: Ne uporabite napolnjenega injekcijskega peresnika, če je zdravilo motno ali obarvano ali vsebuje kosmiče ali delce.
English: If you have forgotten a dose of Aranesp, you should contact your doctor to discuss when you should inject the next dose.
Slovenian: Če ste pozabili odmerek zdravila Aranesp, se pogovorite z zdravnikom, da vam bo povedal, kdaj si injicirajte naslednji odmerek.
English: Severe cutaneous adverse reactions (SCARs) including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which can be life-threatening or fatal, have been reported (see section 4.4).
Slovenian: Poročali so o hudih kožnih neželenih učinkih, vključno s Stevens-Johnsonovim sindromom (SJS) in toksično epidermalno nekrolizo (TEN), ki so lahko življenjsko nevarni ali smrtni (glejte poglavje 4.4).
English: The recommended initial dose is 500 mcg (6.75 mcg/kg) given once every three weeks, or once weekly dosing can be given at 2.25 mcg/kg body weight.
Slovenian: Priporočeni začetni odmerek je 500 µg (6,75 µg/kg) enkrat na tri tedne, uporabiti pa je mogoče tudi odmerjanje 2,25 µg/kg telesne mase enkrat na teden.
English: • Blood clots in a dialysis access
Slovenian: • krvni strdki v pristopu za dializo
English: In clinical studies, an increased risk of death, serious cardiovascular or cerebrovascular events including stroke, and vascular access thrombosis was observed when ESAs were administered to target a haemoglobin of greater than 12 g/dL (7.5 mmol/L).
Slovenian: V kliničnih študijah so ugotovili večje tveganje smrti ter resnih kardiovaskularnih in cerebrovaskularnih dogodkov, vključno z možgansko kapjo in trombozo žilnega pristopa, če so ESA uporabljali tako, da je bil ciljni hemoglobin večji od 120 g/l (7,5 mmol/l).
English: Patients with CRF experienced greater risks for death and serious cardiovascular events when administered ESAs to target higher versus lower haemoglobin levels (13.5 g/dL (8.4 mmol/L) versus 11.3 g/dL (7.1 mmol/L); 14 g/dL (8.7 mmol/L) versus 10 g/dL (6.2 mmol/L) in two clinical studies.
Slovenian: V dveh kliničnih študijah je bilo tveganje smrti in resnih srčno-žilnih dogodkov pri bolnikih s kronično odpovedjo ledvic večje, če je bil cilj zdravljenja z ESA višji hemoglobin, kot če je bil cilj nižji (135 g/l (8,4 mmol/l) v primerjavi z 113 g/l (7,1 mmol/l); 140 g/l (8,7 mmol/l) v primerjavi z 100 g/l (6,2 mmol/l)).
English: Patients with solid tumours (e.g., lung, breast, colon, ovarian cancers) and lymphoid malignancies
Slovenian: Te klinične študije so vključile bolnike s čvrstimi tumorji (npr. rakom pljuč, dojke, kolona, jajčnika) in limfatičnimi malignomi (npr. limfomom, diseminiranim plazmocitomom).
English: The results showed non-inferiority for the primary endpoint of overall survival with a median survival for darbepoetin alfa versus placebo of 9.5 and 9.3 months, respectively (stratified HR 0.92; 95% CI: 0.831.01).
Slovenian: Rezultati so pokazali neinferiornost pri celokupnem preživetju, ki je bilo primarni opazovani dogodek; mediano preživetje je bilo pri zdravljenju z darbepoetinom alfa v primerjavi s placebom 9,5 oziroma 9,3 meseca (stratificirano razmerje ogroženosti 0,92; 95 % IZ: 0,83; 1,01).
English: Meta-analysis of overall survival data produced a hazard ratio point estimate of 1.08 in favour of controls (95% CI: 0.99, 1.18; 42 trials and 8,167 patients).
Slovenian: Ocena ogroženosti na podlagi metaanalize podatkov o celotnem preživetju je bila 1,08 v korist kontrolne skupine (95 % IZ: 0,99, 1,18; 42 preskušanj in 8.167 bolnikov).
English: The terminal half-life of darbepoetin alfa is 21 hours (SD 7.5) when administered intravenously.
Slovenian: Terminalni razpolovni čas intravensko apliciranega darbepoetina alfa je 21 ur (standardni odklon 7,5).
English: • Fluid retention (oedema)
Slovenian: • zastajanje tekočine (edemi)
English: • Avoid injecting into areas with scars or stretch marks.
Slovenian: • Izognite se injiciranju v predele, kjer so brazgotine ali strije.
English: Platelet counts and haemoglobin level should also be monitored at regular intervals.
Slovenian: V rednih presledkih je treba kontrolirati tudi število trombocitov in koncentracijo hemoglobina.
English: In isolated cases, neutralising anti-erythropoietin antibody mediated pure red cell aplasia (PRCA) associated with Aranesp therapy have been reported predominantly in patients with CRF treated subcutaneously.
Slovenian: V posameznih primerih so v povezavi z zdravljenjem z zdravilom Aranesp poročali o čisti aplaziji rdečih celic (PRCA) zaradi nevtralizirajočih protieritropoetinskih protiteles, pretežno pri bolnikih s kronično odpovedjo ledvic, ki so zdravilo dobivali subkutano.
English: For all adults and paediatric patients ≥ 11 years of age not on dialysis, Aranesp could also be given as an injection once monthly.
Slovenian: Vsem odraslim in pediatričnim bolnikom, starim ≥ 11 let, ki niso na dializi, je zdravilo Aranesp možno dati tudi kot injekcijo enkrat na mesec.
English: • Your healthcare provider has prescribed the Aranesp pre-filled pen for injection into the tissue just under the skin (subcutaneous use).
Slovenian: • Zdravstveni delavec vam je predpisal zdravilo Aranesp v napolnjenem injekcijskem peresniku za injiciranje v tkivo tik pod kožo (subkutana uporaba).
English: During the evaluation period (weeks 29-33), the mean (95% CI) weekly equivalent dose was 0.20 (0.17, 0.24) mcg/kg in the once every two week arm and 0.27 (0.23, 0.32) mcg/kg in the once monthly arm.
Slovenian: Med obdobjem ocenjevanja (29. do 33. teden) v tej študiji je bil povprečni (95 % IZ) tedenski ekvivalentni odmerek 0,20 (0,17, 0,24) μg/kg med prejemniki enkrat na dva tedna in 0,27 (0,23, 0,32) μg/kg med prejemniki enkrat na mesec.
English: Excipients: sodium phosphate monobasic, sodium phosphate dibasic, sodium chloride, polysorbate 80, water for injections.
Slovenian: Pomožne snovi: natrijev hidrogenfosfat, natrijev dihidrogenfosfat, natrijev klorid, polisorbat 80, voda za injekcije.
English: Pooled post-hoc analyses of clinical studies of ESAs have been performed in chronic renal failure patients (on dialysis, not on dialysis, in diabetic and non-diabetic patients).
Slovenian: Pri bolnikih s kronično odpovedjo ledvic so izvedli kumulativne post-hoc analize kliničnih študij ESA (bolniki na dializi, bolniki, ki niso na dializi, bolniki s sladkorno boleznijo in bolniki brez sladkorne bolezni).
English: Aranesp is a sterile but unpreserved product.
Slovenian: Zdravilo Aranesp je sterilno, vendar ne vsebuje konzervansov.
English: The secondary endpoint of progression free survival was 4.8 and 4.3 months, respectively (stratified HR 0.95; 95% CI: 0.87-1.04), ruling out the pre-defined 15% risk increase.
Slovenian: Preživetje brez napredovanja bolezni, ki je bilo sekundarni opazovani dogodek, je bilo 4,8 oziroma 4,3 meseca (stratificirano razmerje ogroženosti 0,95; 95 % IZ: 0,87; 1,04), s čimer so izključili predvideno 15 % povečanje tveganja.
English: It must be a clear, colourless or slightly pearly liquid.
Slovenian: Tekočina mora biti bistra, brezbarvna ali rahlo bisernata.
English: At the time of clinical data cutoff, the median progression free survival (PFS) per investigator assessment of disease progression was 7.4 months in each arm (HR 1.09, 95% CI: 0.99, 1.20), indicating the study objective was not met.
Slovenian: Ob zamejitvi kliničnih podatkov je bilo mediano preživetje brez napredovanja bolezni po raziskovalčevi oceni napredovanja bolezni 7,4 meseca v obeh skupinah (razmerje ogroženosti 1,09; 95 % IZ: 0,99; 1,20), kar kaže, da cilj študije ni bil dosežen.
English: Convulsions have been reported in patients receiving darbepoetin alfa (see section 4.4).
Slovenian: Pri bolnikih, ki so dobivali darbepoetin alfa, so poročali o konvulzijah (glejte poglavje 4.4).
English: Alternatively, in patients not on dialysis, the following initial doses can also be administered subcutaneously as a single injection: 0.75 mcg/kg once every two weeks or 1.5 mcg/kg once monthly.
Slovenian: Pri bolnikih, ki niso na dializi, je druga možnost subkutana uporaba sledečih začetnih odmerkov v eni injekciji: 0,75 µg/kg enkrat na dva tedna ali 1,5 µg/kg enkrat na mesec.
English: OTHER Amgen Europe B.V.
Slovenian: Amgen Europe B.V.
English: Non-response to therapy with Aranesp should prompt a search for causative factors.
Slovenian: Če se bolnik na terapijo z zdravilom Aranesp ne odzove, je treba raziskati vzročne dejavnike za to.
English: • Keep the pre-filled pen and all medicines out of the reach of children.
Slovenian: • Napolnjeni injekcijski peresnik in vsa zdravila shranjujte nedosegljivo otrokom!.
English: b Thromboembolic events adverse reactions includes PT embolism, thrombosis, deep vein thrombosis, jugular vein thrombosis, venous thrombosis, arterial thrombosis, pelvic venous thrombosis, peripheral embolism, pulmonary embolism, as well as thrombosis in device from SOC product issues.
Slovenian: b Neželeni učinek trombembolični dogodki vključuje naslednje PT: embolija, tromboza, globoka venska tromboza, tromboza jugularne vene, venska tromboza, arterijska tromboza, tromboza medenične vene, periferna embolija, pljučna embolija ter tudi tromboza v pripomočku za organski sistem “težave povezane z zdravilom”.
English: The vial contains either 25, 40, 60, 100, 200 or 300 micrograms of darbepoetin alfa.
Slovenian: Viala vsebuje 25, 40, 60, 100, 200 ali 300 mikrogramov darbepoetina alfa.
English: Aranesp is available in packs of 1 or 4 pre-filled syringes with automatic needle guard in a blister wrapping.
Slovenian: Zdravilo Aranesp je na voljo v pakiranjih z 1 ali 4 napolnjenimi injekcijskimi brizgami z avtomatičnim ščitnikom igle v pretisnem omotu.
English: • Belly, except for a 5 cm (2-inch) area right around your belly button
Slovenian: • trebuh (razen v predelu 5 cm okrog popka)
English: At the time haemoglobin ≥ 10.0 g/dL was first achieved, the mean (SD) weightadjusted dose was 0.48 (0.24) mcg/kg (range: 0.0 to 1.7 mcg/kg) weekly for the once weekly group and 0.76 (0.21) mcg/kg (range: 0.3 to 1.5 mcg/kg) biweekly for the once every two week group.
Slovenian: V času, ko je bila prvič dosežena koncentracija hemoglobina ≥ 100 g/l, je bil povprečni (standardni odklon) na telesno maso prilagojeni odmerek 0,48 (0,24) µg/kg (razpon: 0,0 do 1,7 µg/kg) na teden v skupini z uporabo vsak teden ter 0,76 (0,21) µg/kg (razpon: 0,3 do 1,5 µg/kg) na dva tedna v skupini z uporabo vsaka dva tedna.
English: Aranesp is used to treat symptomatic anaemia in adult cancer patients with non-bone marrow cancers (non-myeloid malignancies) who are receiving chemotherapy.
Slovenian: Zdravilo Aranesp uporabljamo za zdravljenje simptomatske anemije pri odraslih bolnikih, ki imajo raka, ki ne izhaja iz kostnega mozga (nemieloičnega raka), in dobivajo kemoterapijo.
English: A tendency towards increased risk estimates for all-cause mortality, cardiovascular and cerebrovascular events associated with higher cumulative ESA doses independent of the diabetes or dialysis status was observed (see sections 4.2 and 4.4).
Slovenian: Ob višjih kumulativnih odmerkih ESA so opažali nagnjenost k višjim ocenam tveganja za umrljivost zaradi vseh vzrokov ter za kardiovaskularne in cerebrovaskularne dogodke; to ni bilo odvisno od prisotnosti ali odsotnosti sladkorne bolezni ali od dializnega stanja (glejte poglavji 4.2 in 4.4).
English: In a prospective, randomised double-blind, placebo-controlled study conducted in 344 anaemic patients with lymphoproliferative malignancies receiving chemotherapy there was a significant reduction in transfusion requirements and an improvement in haemoglobin response (p < 0.001).
Slovenian: V prospektivni, randomizirani, dvojno slepi s placebom kontrolirani študiji pri 344 anemičnih bolnikih z limfoproliferativnimi malignomi, ki so dobivali kemoterapijo, so ugotovili značilno zmanjšanje potreb po transfuziji in boljši odziv hemoglobina (p < 0,001).
English: In a clinical study in 124 paediatric patients with chronic kidney disease receiving or not receiving dialysis aged 1 to 18, patients that were stable on epoetin alfa were randomised to receive either darbepoetin alfa administered once weekly (subcutaneously or intravenously) using a dose conversion ratio of 238:1 or to continue with epoetin alfa therapy at the current dose, schedule, and route of administration.
Slovenian: V klinični študiji so 124 pediatričnih bolnikov, starih od 1 do 18 let s kronično boleznijo ledvic in zdravljenih ali nezdravljenih z dializo, ki so bili stabilni na epoetinu alfa, randomizirali na uporabo darbepoetina alfa (subkutano ali intravensko) s konverzijskim razmerjem odmerka 238:1 ali na nadaljnjo zdravljenje z epoetinom alfa v trenutnem odmerku, shemi in poti uporabe.
English: Erythropoietin is a growth factor that primarily stimulates red blood cell production.
Slovenian: Eritropoetini so rastni dejavniki, ki spodbujajo predvsem nastajanje rdečih krvnih celic.
English: Source: includes 8 randomised, double-blind, placebo-controlled studies (980291-schedule 1 and 2, 980297, 990114, 20000161, 20010145, 20030232, and 20070782) a Hypersensitivity events includes all events under the hypersensitivity SMQ.
Slovenian: Vir: vključenih je 8 randomiziranih, dvojno slepih, s placebom kontroliranih študij (980291 - shemi 1 in 2, 980297, 990114, 20000161, 20010145, 20030232 in 20070782).
English: The frequency is estimated from clinical trial data as common in cancer patients and was also common in the placebo groups.
Slovenian: Na podlagi podatkov iz kliničnih preskušanj je pogostnost pri onkoloških bolnikih ocenjena kot pogosta; pogosta je bila tudi v skupinah s placebom.
English: If you miss a dose of Aranesp, you should contact your doctor to discuss when you should receive the next dose.
Slovenian: Če ste pozabili odmerek zdravila Aranesp, se pogovorite z zdravnikom, da vam bo povedal, kdaj morate prejeti naslednji odmerek.
English: Step 3: Inject G Hold the stretch or pinch.
Slovenian: 3. korak: Injiciranje G Kožo držite raztegnjeno ali stisnjeno v gubo.
English: Your doctor has decided that the Aranesp pre-filled pen is the best way for you, a nurse or a carer to inject Aranesp.
Slovenian: Zdravnik je uporabo napolnjenega injekcijskega peresnika Aranesp ocenil kot najboljši način, da si zdravilo injicirate sami, da vam ga injicira medicinska sestra ali oseba, ki skrbi za vas.
English: Haemoglobin variability should be addressed through dose management, with consideration for the haemoglobin target range of 10 g/dL (6.2 mmol/L) to 12 g/dL (7.5 mmol/L).
Slovenian: Variabilnosti hemoglobina se je treba prilagoditi z uravnavanjem odmerka, pri čemer je treba upoštevati ciljno območje koncentracije hemoglobina od 100 g/l (6,2 mmol/l) do 120 g/l (7,5 mmol/l).
English: The initial dose by subcutaneous or intravenous administration is 0.45 mcg/kg body weight, as a single injection once weekly.
Slovenian: Začetni subkutani ali intravenski odmerek je 0,45 µg/kg telesne mase v eni injekciji enkrat na teden.
English: Put the used pre-filled pen in the sharps disposal container immediately after use.
Slovenian: Uporabljen napolnjen injekcijski peresnik nemudoma po uporabi dajte v vsebnik za ostre odpadke.
English: Median overall survival in the epoetin alfa plus SOC group was 17.8 months compared with 18.0 months in the SOC alone group (HR 1.07, 95% CI: 0.97, 1.18).
Slovenian: Mediano celokupno preživetje v skupini z epoetinom alfa in standardno oskrbo je bilo 17,8 meseca v primerjavi z 18,0 meseca v skupini s samo standardno oskrbo (razmerje ogroženosti 1,07; 95 % IZ: 0,97; 1,18).
English: Intercurrent infections, inflammatory or traumatic episodes, occult blood loss, haemolysis, severe aluminium toxicity, underlying haematologic diseases, or bone marrow fibrosis may also compromise the erythropoietic response.
Slovenian: Eritropoetski odziv lahko poslabšajo tudi sočasne okužbe, vnetja ali poškodbe, prikrito izgubljanje krvi, hemoliza, huda toksičnost aluminija, osnovne hematološke bolezni ali fibroza kostnega mozga.
English: • plan to get pregnant.
Slovenian: • nameravate zanositi.
English: You may change the injection site if you notice the area is red or sore.
Slovenian: Mesto injiciranja lahko zamenjate, če je predel pordel ali boli.
English: K Examine the injection site.
Slovenian: B Preglejte mesto injiciranja.
English: • shortened overall survival and increased deaths attributed to disease progression at 4 months in patients with metastatic breast cancer receiving chemotherapy when administered to target a haemoglobin of 12-14 g/dL (7.5-8.7 mmol/L).
Slovenian: • skrajšala celotno preživetje in povečala število smrti, ki jih je bilo mogoče pripisati napredovanju bolezni po 4 mesecih, pri bolnicah z metastatskim rakom dojke, zdravljenih s kemoterapijo, če je bila ciljna vrednost hemoglobina od 120 do 140 g/l (od 7,5 do 8,7 mmol/l).
English: This has been predominantly reported in patients with CRF treated subcutaneously.
Slovenian: O tem so poročali predvsem pri bolnikih s kronično odpovedjo ledvic, ki so zdravilo dobivali subkutano.
English: In a randomised, double-blind, placebo-controlled phase 3 study 2,549 adult patients with anaemia receiving chemotherapy for the treatment of advanced stage non-small cell lung cancer (NSCLC), were randomised 2:1 to darbepoetin alfa or placebo and treated to a maximum Hb of 12 g/dL.
Slovenian: V randomizirani, dvojno slepi, s placebom kontrolirani študiji faze 3 je sodelovalo 2.549 odraslih bolnikov z anemijo, zdravljenih s kemoterapijo za zdravljenje napredovalega nedrobnoceličnega raka pljuč, ki so jih randomizirali v razmerju 2 : 1 v skupini z darbepoetinom alfa ali placebom in zdravili do največje koncentracije Hb 120 g/l.
English: In a randomised clinical study 114 paediatric patients aged 2 to 18 with chronic kidney disease receiving or not receiving dialysis who were anaemic (haemoglobin < 10.0 g/dL) and not being treated with an ESA were administered darbepoetin alfa weekly (n = 58) or once every two weeks (n = 56) for the correction of anaemia.
Slovenian: V randomizirani klinični študiji je 114 pediatričnih bolnikov, starih od 2 do 18 let s kronično boleznijo ledvic in zdravljenih ali nezdravljenih z dializo, ki so bili anemični (hemoglobin < 100 g/l) in niso prejemali ESA, za korekcijo anemije dobivalo darbepoetin alfa vsak teden (n = 58) ali vsaka dva tedna (n = 56).
English: Pack size of 1 or 4 vials.
Slovenian: Pakiranje vsebuje 1 ali 4 viale.
English: Pharmacokinetic parameters did not change on multiple dosing over 12 weeks (dosing every week or every two weeks).
Slovenian: Med večkratnim odmerjanjem v teku 12 tednov (odmerjanje vsak teden ali na dva tedna) se farmakokinetični parametri niso spremenili.
English: Following subcutaneous administration of 2.25 mcg/kg to adult cancer patients a mean peak concentration of 10.6 ng/mL (SD 5.9) of darbepoetin alfa was reached at a mean time of 91 hours (SD 19.7).
Slovenian: Pri odraslih onkoloških bolnikih je darbepoetin alfa po subkutani uporabi 2,25 µg/kg dosegel povprečno največjo koncentracijo 10,6 ng/ml (standardni odklon 5,9) v povprečno 91 urah (standardni odklon 19,7).
English: Additionally, do not leave the syringe exposed to direct sunlight.
Slovenian: Pazite tudi, da injekcijska brizga ne bo izpostavljena neposredni sončni svetlobi.
English: For all adult and paediatric patients ≥ 1 year of age with chronic renal failure, once your anaemia is corrected you will continue to receive Aranesp given as a single injection, either once a week or once every two weeks.
Slovenian: Vsi odrasli in pediatrični bolniki, stari ≥ 1 leta, s kronično odpovedjo ledvic bodo po korekciji anemije še naprej prejemali zdravilo Aranesp kot eno injekcijo enkrat na teden ali enkrat na dva tedna.
English: Your doctor, nurse or pharmacist will show you how to inject yourself with the pre-filled syringe.
Slovenian: Zdravnik, medicinska sestra ali farmacevt vam bodo pokazali, kako si zdravilo injicirate z napolnjeno injekcijsko brizgo.
English: PRCA means that the body has stopped or reduced the production of red blood cells which causes severe anaemia.
Slovenian: Čista aplazija rdečih celic pomeni, da so v telesu nehale nastajati rdeče krvne celice ali pa je njihovo nastajanje zmanjšano; posledica je huda anemija.
English: placebo-controlled studies of Aranesp with a total of 4,630 patients (Aranesp 2,888, placebo 1,742).
Slovenian: Aranesp 2.888, placebo 1.742).
English: Leave the pre-filled pen at room temperature for at least 30 minutes before injecting.
Slovenian: Pustite napolnjen injekcijski peresnik na sobni temperaturi vsaj za 30 minut, preden začnete z injiciranjem.
English: You may notice a small air bubble in the pre-filled syringe.
Slovenian: V napolnjeni injekcijski brizgi boste morda opazili majhen mehurček zraka.
English: Stop using Aranesp if you develop these symptoms and contact your doctor or seek medical attention immediately.
Slovenian: Če se vam pojavijo ti simptomi, takoj prenehajte uporabljati zdravilo Aranesp in se nemudoma posvetujte s svojim zdravnikom ali nemudoma poiščite zdravniško pomoč.
English: Aranesp contains sodium
Slovenian: Zdravilo Aranesp vsebuje natrij
English: You could have serious problems if you use more Aranesp than you need, such as very high blood pressure.
Slovenian: Če ste uporabili večji odmerek zdravila Aranesp, kot bi smeli Če uporabite večji odmerek zdravila Aranesp, kot bi smeli, se vam lahko pojavijo resne težave, kot je zelo visok krvni tlak.
English: • Keep the pre-filled pen in the outer carton in order to protect from light or physical damage.
Slovenian: • Napolnjen injekcijski peresnik shranjujte v zunanji ovojnini za zagotovitev zaščite pred svetlobo ali poškodbo.
English: Marketing Authorisation Holder and Manufacturer Amgen Europe B.V.
Slovenian: Imetnik dovoljenja za promet z zdravilom in proizvajalec Amgen Europe B.V.
English: Once removed from the refrigerator and has reached room temperature (up to 25ºC) it must either be used within 7 days or disposed of.
Slovenian: Ko ga vzamete iz hladilnika in doseže sobno temperaturo (do 25 °C), ga morate uporabiti v 7 dneh, sicer ga morate zavreči.
English: You could have serious problems if you receive more Aranesp than you need, such as very high blood pressure.
Slovenian: Če ste uporabili večji odmerek zdravila Aranesp, kot bi smeli Če dobite večji odmerek zdravila Aranesp, kot bi smeli, se vam lahko pojavijo resne težave, kot je zelo visok krvni tlak.
English: The Aranesp (SureClick) pre-filled pen delivers the complete dose of each presentation.
Slovenian: Zdravilo Aranesp (SureClick) v napolnjenem injekcijskem peresniku zagotavlja celoten odmerek v vsakem pakiranju.
English: In these patients, erythropoietin deficiency and a reduced response of erythroid progenitor cells to endogenous erythropoietin both contribute significantly towards their anaemia.
Slovenian: Pri teh bolnikih k anemiji bistveno pripomoreta tako pomanjkanje eritropoetina kot slabši odziv eritroidnih matičnih celic na endogeni eritropoetin.
English: Aranesp 40 µg injection Darbepoetin alfa IV/SC
Slovenian: Aranesp 40 µg Darbepoetin alfa i.v./s.c.
English: • a new Aranesp pre-filled syringe; and
Slovenian: • novo napolnjeno injekcijsko brizgo zdravila Aranesp in • alkoholne zložence ali podobno.
English: Step 2: Get ready E Pull the grey cap straight off, only when you are ready to inject.
Slovenian: 2. korak: Pripravite se E Ko ste pripravljeni na injiciranje, potegnite sivi pokrovček igle naravnost s peresnika.
English: Treatment of symptomatic chemotherapy-induced anaemia in cancer patients
Slovenian: Zdravljenje simptomatske anemije zaradi kemoterapije pri onkoloških bolnikih
English: Aranesp is supplied ready for use in a vial.
Slovenian: Zdravilo Aranesp je pripravljeno za uporabo v viali.