FrancophonIA/ELRC3.0 huggingface dataset:
English: For passive immunisation of broilers induced by active immunisation of female broiler breeders to reduce infection with Ornithobacterium rhinotracheale serotype A when this agent is involved.
Slovenian: Pasivna imunizacija brojlerjev z aktivno imunizacijo živali ženskega spola v brojlerskih matičnih jatah za zmanjšanje okužbe z Ornithobacterium rhinotracheale serotipa A, kadar je ta bakterija prisotna.
English: Inactivated whole cell suspension of Ornithobacterium rhinotracheale serotype A, strain B3263/91 1 x 107 cells * * inducing a mean titre in the chickens of the potency test of at least 11.2 (log2).
Slovenian: Inaktivirana suspenzija celic bakterije Ornithobacterium rhinotracheale, serotip A, sev B3263/91 1 x 107 celic* *pri preizkusu učinkovitosti pri piščancih spodbudi nastanek srednjega titra, ki je najmanj 11,2 (log2) Dodatek
English: * inducing a mean titre in the chickens of the potency test of at least 11.2 (log2).
Slovenian: *pri preizkusu učinkovitosti pri piščancih spodbudi nastanek srednjega titra, ki je najmanj 11,2 (log2) Redko tekoči parafin: 107,21 mg
English: The vaccine is to stimulate active immunity in broiler breeders in order to provide passive immunity to the progeny against Ornithobacterium rhinotracheale serotype A.
Slovenian: Cepivo uporabljamo za spodbujanje aktivne imunosti pri brojlerskih matičnih jatah, da bi vzbudili pasivno imunost potomcev proti Ornithobacterium rhinotracheale, serotip A.
English: Do not use in birds in lay.
Slovenian: Ne uporabljajte v obdobju valjenja.
English: THE WORDS "KEEP OUT OF THE REACH AND SIGHT OF CHILDREN" Keep out of the reach and sight of children
Slovenian: BESEDILO ''ZDRAVILO SHRANJUJTE NEDOSEGLJIVO OTROKOM'' Zdravilo shranjujte nedosegljivo otrokom.
English: injection of one dose of 0.25 ml.
Slovenian: POTI UPORABE En odmerek po 0,25 ml s.c. ali i.m.
English: Adjuvant
Slovenian: INDIKACIJE
English: A. MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURING AUTHORISATION HOLDER RESPONSIBLE FOR BATCH RELEASE
Slovenian: A. IZDELOVALEC(IZDELOVALCI) BIOLOŠKE ZDRAVILNE UČINKOVINE (ZDRAVILNIH UČINKOVIN) IN IMETNIK(I) DOVOLJENJ(A) ZA IZDELAVO ZDRAVILA, ODGOVOREN(ODGOVORNI) ZA SPROŠČANJE SERIJE
English: THE WORDS "FOR ANIMAL TREATMENT ONLY" For animal treatment only.
Slovenian: BESEDILO SAMO ZA ŽIVALI Samo za živali.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Per dose of 0.25 ml:
Slovenian: KAKOVOSTNA IN KOLIČINSKA SESTAVA
English: Once broached: Use immediately
Slovenian: Rok uporabnosti po prvem odpiranju vsebnika: Uporabite takoj po pripravi.
English: Subcutaneous injection in the neck or intramuscular injection in the breast of the chicken.
Slovenian: Enkratni odmerek po 0,25 ml. Subkutano na vratu ali intramuskularno v prsni predel.
English: CONDITIONS OR RESTRICTIONS OF THE MARKETING AUTHORISATION REGARDING SUPPLY ORUSE
Slovenian: POGOJI DOVOLJENJA ZA PROMET Z ZDRAVILOM TER OMEJITVE GLEDE OSKRBE IN UPORABE
English: DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION Single dose of 0.25 ml.
Slovenian: ODMERKI ZA POSAMEZNE ŽIVALSKE VRSTE TER POT(I) IN NAČIN UPORABE ZDRAVILA
English: Active substance
Slovenian: Pomožne snovi
English: Pack size blister (PVC/PE/PVDC/alu)
Slovenian: Velikost pakiranja pretisni omot (PVC/PE/PVDC/alu)
English: 30 mg Film-coated tablet Oral use
Slovenian: 30 mg Filmsko obložena tableta
English: This overview was last updated in 03-2018.
Slovenian: Pregled je bil nazadnje posodobljen 03-2018.
English: Further information on Invirase can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Več informacij o zdravilu Invirase je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: These studies measured the viral load after 48 weeks.
Slovenian: V teh študijah so izmerili virusno breme po 48 tednih.
English: What measures are being taken to ensure the safe and effective use of Invirase?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Invirase?
English: The European Medicines Agency decided that Invirase's benefits are greater than its risks and it can be authorised for use in the EU.
Slovenian: Evropska agencija za zdravila je zaključila, da so koristi zdravila Invirase večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
English: Invirase received a marketing authorisation valid throughout the EU on 4 October 1996.
Slovenian: Za zdravilo Invirase je bilo 4. oktobra 1996 izdano dovoljenje za promet, veljavno po vsej EU.
English: Invirase was found effective in the treatment of HIV infection in six main studies involving a total of 1,576 patients.
Slovenian: Zdravilo Invirase se je pokazalo kot učinkovito pri zdravljenju okužbe z virusom HIV v šestih glavnih študijah, v katere je bilo skupno vključenih 1 576 bolnikov.
English: Invirase is available as capsules (200 mg) and tablets (500 mg).
Slovenian: Zdravilo Invirase je na voljo v obliki kapsul (200 mg) in tablet (500 mg).
English: What is Invirase and what is it used for?
Slovenian: Kaj je zdravilo Invirase in za kaj se uporablja?
English: It must not be used in patients who have had arrhythmia (unstable heartbeat).
Slovenian: Ne sme se uporabljati pri bolnikih, ki so imeli aritmijo (nestabilen srčni utrip).
English: • medicines that could cause QT prolongation or PR prolongation (another type of heart activity alteration);
Slovenian: • zdravila, ki bi lahko povzročila podaljšanje intervala QT ali PR (druga vrsta spremembe delovanja srca);
English: Invirase (saquinavir)
Slovenian: Invirase (sakvinavir)
English: What benefits of Invirase have been shown in studies?
Slovenian: Kakšne koristi zdravila Invirase so se pokazale v študijah?
English: Why is Invirase authorised in the EU?
Slovenian: Zakaj je bilo zdravilo Invirase odobreno v EU?
English: As for all medicines, data on the use of Invirase are continuously monitored.
Slovenian: Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila Invirase stalno spremljajo.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Invirase have been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Invirase upoštevati zdravstveni delavci in bolniki, so vključeni v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: It must also not be used in patients who are taking any of the following medicines which could cause harmful side effects if taken with Invirase:
Slovenian: Prav tako se ne sme uporabljati pri bolnikih, ki jemljejo katero od naslednjih zdravil, saj bi lahko ta ob sočasnem jemanju z zdravilom Invirase povzročila škodljive neželene učinke:
English: This allows effective treatment while avoiding a higher dose of saquinavir.
Slovenian: To prispeva k učinkovitemu zdravljenju in hkrati omogoča, da bolniku ni treba prejemati višjega odmerka sakvinavirja.
English: Side effects reported with Invirase are carefully evaluated and any necessary action taken to protect patients.
Slovenian: Neželeni učinki, o katerih so poročali pri zdravilu Invirase, se skrbno ovrednotijo in po potrebi se lahko sprejmejo ukrepi za zaščito bolnikov.
English: An overview of Invirase and why it is authorised in the EU
Slovenian: Pregled zdravila Invirase in zakaj je odobreno v EU
English: • ergot alkaloids, such as ergotamine, dihydroergotamine, ergonovine and methylergonovine (used to treat migraine headache);
Slovenian: • ergot alkaloidi, kot so ergotamin, dihidroergotamin, ergonovin in metilergonovin (uporabljajo se za zdravljenje migrenskega glavobola);
English: Invirase is an antiviral medicine used to treat adults infected with the human immunodeficiency virus type 1 (HIV 1), a virus that causes acquired immune deficiency syndrome (AIDS).
Slovenian: Invirase je protivirusno zdravilo, ki se uporablja za zdravljenje odraslih, okuženih z virusom humane imunske pomanjkljivosti tipa 1 (HIV 1), tj. virusom, ki povzroča sindrom pridobljene imunske pomanjkljivosti (aids).
English: Two further studies involving 656 patients compared Invirase with indinavir or lopinavir (other HIV medicines).
Slovenian: V dveh drugih študijah s 656 bolniki so zdravilo Invirase primerjali z indinavirjem ali lopinavirjem (drugima zdraviloma za zdravljenje okužbe z virusom HIV).
English: • rifampicin (used to treat tuberculosis);
Slovenian: • rifampicin (uporablja se za zdravljenje tuberkuloze);
English: When the enzyme is blocked, the virus does not reproduce normally, slowing down the spread of infection.
Slovenian: Ko je encim zavrt, se virus ne more več normalno razmnoževati, kar zmanjša hitrost širjenja okužbe.
English: Other information about Invirase
Slovenian: Druge informacije o zdravilu Invirase
English: What are the risks associated with Invirase?
Slovenian: Kakšna tveganja so povezana z zdravilom Invirase?
English: Invirase must not be used in patients who have severe problems with their liver, QT prolongation (an alteration of the electrical activity of the heart), abnormal levels of electrolytes in the blood (especially low potassium levels), bradycardia (slow heart rate) or heart failure (when the heart does not work as well as it should).
Slovenian: Zdravilo Invirase se ne sme uporabljati pri bolnikih, ki imajo hude težave z jetri, podaljšanje intervala QT (sprememba električnega delovanja srca), nenormalne ravni elektrolitov v krvi (zlasti nizko raven kalija), bradikardijo (upočasnjen srčni ritem) ali srčno popuščanje (pri katerem srce ne deluje tako dobro, kot bi moralo).
English: It slows the breakdown of saquinavir, increasing the levels of saquinavir in the blood.
Slovenian: Upočasnjuje hitrost razgradnje sakvinavirja in s tem povečuje njegovo raven v krvi.
English: Ritonavir is another protease inhibitor that is used as a ‘booster'.
Slovenian: Ritonavir je drug zaviralec proteaze, ki se uporablja kot „ojačevalec“.
English: For more information about using Invirase, see the package leaflet or contact a doctor or pharmacist.
Slovenian: Za več informacij glede uporabe zdravila Invirase glejte navodilo za uporabo ali se posvetujte z zdravnikom ali farmacevtom.
English: It blocks protease, an enzyme involved in the reproduction of HIV.
Slovenian: Zavira proteazo, tj. encim, ki sodeluje pri razmnoževanju virusa HIV.
English: Invirase can only be obtained with a prescription and treatment should be started by a doctor who has experience in the treatment of HIV infection.
Slovenian: Predpisovanje in izdaja zdravila Invirase je le na recept, zdravljenje z njim pa mora uvesti zdravnik, ki ima izkušnje z zdravljenjem okužb z virusom HIV.
English: Invirase does not cure HIV infection or AIDS, but it may hold off the damage to the immune system and the development of infections and diseases associated with AIDS.
Slovenian: Zdravilo Invirase ne ozdravi okužbe z virusom HIV ali aidsa, lahko pa upočasni slabšanje imunskega sistema ter razvoj okužb in bolezni, povezanih z aidsom.
English: Invirase should only be used in combination with ritonavir (another antiviral medicine) and other antiviral medicines.
Slovenian: Zdravilo Invirase se uporablja samo v kombinaciji z ritonavirjem (drugim protivirusnim zdravilom) in drugimi protivirusnimi zdravili.
English: • simvastatin, lovastatin (used to lower cholesterol);
Slovenian: • simvastatin, lovastatin (uporabljata se za zniževanje holesterola);
English: The most common side effects when taking Invirase in combination with ritonavir (which may affect more than 1 patient in 10) are diarrhoea, nausea (feeling sick), increased levels of liver enzymes, cholesterol and triglycerides (a type of fat) in the blood, and decreased levels of platelets in the blood (components that help blood to clot).
Slovenian: Najpogostejši neželeni učinki pri jemanju zdravila Invirase v kombinaciji z ritonavirjem (ki se lahko pojavijo pri več kot 1 bolniku od 10) so driska, navzea (siljenje na bruhanje), zvišane ravni jetrnih encimov, holesterola in trigliceridov (vrste maščobe) v krvi ter znižane ravni trombocitov v krvi (celic, ki pomagajo pri strjevanju krvi).
English: In the first four studies, Invirase in combination with other HIV medicines, but without ritonavir, reduced the viral load and improved the immune system.
Slovenian: V prvih štirih študijah je zdravilo Invirase v kombinaciji z drugimi zdravili za zdravljenje okužbe z virusom HIV, vendar brez ritonavirja, zmanjšalo virusno breme in okrepilo imunski sistem.
English: Invirase, taken in combination with other HIV medicines, reduces the viral load (the amount of HIV in the blood) and keeps it at a low level.
Slovenian: Zdravilo Invirase v kombinaciji z drugimi zdravili za zdravljenje okužbe z virusom HIV zmanjša virusno breme (količino virusa HIV v krvi) in ga ohranja na nizki ravni.
English: For patients already taking HIV medicines, the recommended dose of Invirase is 1,000 mg with 100 mg ritonavir twice daily.
Slovenian: Za bolnike, ki že jemljejo zdravila za zdravljenje okužbe z virusom HIV, je priporočeni odmerek zdravila Invirase 1 000 mg s 100 mg ritonavirja dvakrat na dan.
English: The medicines were given in combination with ritonavir and two other HIV medicines.
Slovenian: Zdravila so dajali v kombinaciji z ritonavirjem in dvema drugima zdraviloma za zdravljenje okužbe z virusom HIV.
English: • lurasidone, quetiapine (used to treat psychiatric illness such as schizophrenia).
Slovenian: • lurazidon, kvetiapin (uporabljata se za zdravljenje duševnih motenj, kot je shizofrenija).
English: After 7 days, the recommended dose of Invirase is 1,000 mg twice daily with ritonavir 100 mg twice daily in combination with other HIV medicines.
Slovenian: Po sedmih dneh znaša priporočeni odmerek zdravila Invirase 1 000 mg dvakrat na dan skupaj s 100 mg ritonavirja dvakrat na dan v kombinaciji z drugimi zdravili za zdravljenje okužbe z virusom HIV.
English: • midazolam taken by mouth, triazolam (used to relieve anxiety or difficulty sleeping);
Slovenian: • midazolam za peroralno uporabo, triazolam (uporabljata se za lajšanje tesnobnosti ali težav s spanjem);
English: Invirase contains the active substance saquinavir.
Slovenian: Zdravilo Invirase vsebuje zdravilno učinkovino sakvinavir.
English: For patients who are not taking HIV medicines, Invirase is started at 500 mg twice daily with ritonavir 100 mg twice daily for the first 7 days of treatment, given in combination with other HIV medicines.
Slovenian: Pri bolnikih, ki zdravil za zdravljenje okužbe z virusom HIV še ne jemljejo, se zdravilo Invirase uvede v odmerku 500 mg dvakrat na dan s 100 mg ritonavirja dvakrat na dan v prvih sedmih dneh zdravljenja, pri čemer se daje v kombinaciji z drugimi zdravili.
English: Invirase in combination with ritonavir was as effective as indinavir but more effective than lopinavir in reducing the viral load to less than 50 copies/ml.
Slovenian: V študijah, v katerih so zdravilo Invirase proučevali v kombinaciji z ritonavirjem, je bilo zdravilo Invirase pri zmanjševanju virusnega bremena na manj kot 50 kopij/ml enako učinkovito kot indinavir in učinkovitejše od lopinavirja.
English: The active substance in Invirase, saquinavir, is a ‘protease inhibitor'.
Slovenian: Učinkovina v zdravilu Invirase, sakvinavir, je zaviralec proteaze.
English: How is Invirase used?
Slovenian: Kako se zdravilo Invirase uporablja?
English: For the full list of side effects of Invirase, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Invirase, glejte navodilo za uporabo.
English: How does Invirase work?
Slovenian: Kako zdravilo Invirase deluje?
English: Main outcomes of this study are presented in this table:
Slovenian: Glavni izidi te študije so predstavljeni v tej preglednici:
English: You may become sleepy and could lose consciousness.
Slovenian: Lahko postanete zaspani in zgubite zavest.
English: In children, this combination is not recommended.
Slovenian: Pri otrocih ta kombinacija ni priporočljiva.
English: IF ANY OF THE FOLLOWING OCCUR, THE CHILD NEEDS URGENT MEDICAL ATTENTION:
Slovenian: ČE SE ZGODI KAR KOLI OD NASLEDNJEGA, MORDA OTROK POTREBUJE NUJNO ZDRAVNIŠKO POMOČ:
English: The effects at this dose level were reversible during the recovery period.
Slovenian: Učinki na tej ravni odmerka so bili reverzibilni v obdobju okrevanja.
English: Your doctor may need to monitor or treat this.
Slovenian: Vaš zdravnik bo morda moral to spremljati ali zdraviti.
English: very rare not known cannot be estimated from the available data
Slovenian: zelo redki neznana ni mogoče oceniti iz razpoložljivih podatkov
English: The duration of low bicarbonate measurements was also long (median 188 days).
Slovenian: Tudi trajanje nizkih izmerjenih ravni bikarbonata je bilo dolgo (mediana 188 dni).
English: Children and adolescents Talk to your doctor about the following risks:
Slovenian: Otroci in mladostniki Z zdravnikom se posvetujte o naslednjih tveganjih:
English: In addition there has been extensive post-marketing experience with zonisamide in Japan since 1989 and in the USA since 2000.
Slovenian: Poleg tega obstajajo obširne izkušnje z zonisamidom v obdobju trženja na Japonskem od leta 1989 in v ZDA od leta 2000.
English: Most reports occurred during periods of warm weather.
Slovenian: Večina teh primerov se je zgodila v obdobjih toplega vremena.
English: Steady state was achieved within 13 days.
Slovenian: Stanje dinamičnega ravnovesja je bilo doseženo v trinajstih dneh.
English: PC: SN:
Slovenian: PC: SN: NN:
English: They occur during the first month of treatment and usually decrease with continued treatment.
Slovenian: Pojavljajo se med prvim mesecem zdravljenja in običajno z nadaljevanjem zdravljenja izzvenijo.
English: Do not give this medicine to children below the age of 6 years because it is not known for this age group whether the potential benefits are greater than the risks.
Slovenian: Tega zdravila ne dajajte otrokom, starim manj kot 6 let, saj za to starostno skupino ni znano, ali so morebitne koristi večje od tveganj.
English: Note: * All doses are once daily.
Slovenian: Opomba: * Vsi odmerki so enkrat na dan.
English: General supportive care is indicated, including frequent monitoring of vital signs and close observation.
Slovenian: Indicirana je splošna podporna terapija, vključno s pogostim spremljanjem vitalnih znakov in skrbnim opazovanjem.
English: Altogether, data on effects on long-term growth and development are limited.
Slovenian: Na splošno so podatki o učinku na dolgoročno rast in razvoj omejeni.
English: Suicide ideation and behaviour
Slovenian: Samomorilno razmišljanje in vedenje
English: Make sure you are fully informed about the risks and the benefits of using zonisamide for epilepsy during pregnancy.
Slovenian: Prepričajte se, da ste o tveganjih in koristih uporabe zonisamida za epilepsijo med nosečnostjo v celoti obveščeni.
English: Zonisamide was not genotoxic and has no carcinogenic potential.
Slovenian: Zonisamid ni genotoksičen in nima kancerogenega potenciala.
English: • Keep the child's skin cool with water
Slovenian: • otrokovo kožo hladite z vodo,
English: PP = Per Protocol Population; ITT = Intent To Treat Population *Primary endpoint
Slovenian: PP = populacija po protokolu; ITT = populacija z namenom zdravljenja *Primarni opazovani dogodek
English: The mechanism of this risk is not known and the available data do not exclude the possibility of an increased risk for zonisamide.
Slovenian: Mehanizem tveganja še ni znan, vendar razpoložljivi podatki ne izključujejo možnosti povečanega tveganja pri zonisamidu.
English: Paediatric Population).
Slovenian: Pediatrična populacija).
English: Tell your doctor as this may need to be monitored.
Slovenian: O tem obvestite zdravnika, ker bo mogoče to treba spremljati;
English: Studies in animals have shown changes in fertility parameters.
Slovenian: Študije na živalih so pokazale spremembe v parametrih plodnosti.
English: When a child is taking zonisamide:
Slovenian: Če otrok jemlje zonisamid:
English: incontinence), status epilepticus (prolonged or repeated seizures)
Slovenian: inkontinenca), epileptični status (dolgotrajen ali ponavljajoč se napad krčev);
English: The dose should be titrated on the basis of clinical effect.
Slovenian: Odmerek je treba titrirati na podlagi kliničnega učinka.
English: Do not try to drive.
Slovenian: V tem času ne vozite avtomobila.
English: - Zonisamide Mylan can be taken once or twice daily, as instructed by your doctor.
Slovenian: - Zdravilo Zonisamid Mylan lahko jemljete enkrat ali dvakrat na dan, kot vam je naročil zdravnik.
English: Titration Phase
Slovenian: Faza titriranja
English: • Body weight: You should monitor your child's weight every month and see your doctor as soon as possible if your child is not gaining enough weight.
Slovenian: • Telesna masa: vsak mesec spremljajte telesno maso svojega otroka in pojdite k zdravniku takoj, ko lahko, če otrok ne pridobiva ustrezno na telesni masi.
English: In these cases it is therefore recommended that the zonisamide total dose should be rounded up or down to the nearest available dose that can be achieved with commercially available capsule strengths of zonisamide (25 mg, 50 mg and 100 mg).
Slovenian: Zato v teh primerih priporočajo, naj se celotni odmerek zonisamida zaokroži navzgor ali navzdol do najbližjega razpoložljivega odmerka, ki ga je možno doseči z jakostmi kapsul zonisamida, ki so komercialno na voljo (25 mg, 50 mg in 100 mg).
English: At a higher dose level (2-3-fold systemic exposure compared to therapeutic exposure) renal histopathological effects were more severe and only partially reversible.
Slovenian: Pri višjih ravneh odmerka (2-3-kratna sistemska izpostavljenost v primerjavi s terapevtsko izpostavljenostjo) so bili ledvični histopatološki učinki resnejši in le delno reverzibilni.
English: - Do not chew the capsules.
Slovenian: - Kapsul ne žvečite.
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency: http://www.ema.europa.eu
Slovenian: Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila http://www.ema.europa.eu.
English: Some patients may respond to lower doses.
Slovenian: Nekateri bolniki se lahko odzovejo že na manjše odmerke.
English: Example: A child who weighs 25 kg should take 25 mg once a day for the first week, and then increase the daily dose by 25 mg at the start of each week until a daily dose between 150 to 200 mg is reached.
Slovenian: Primer: Otrok, ki tehta 25 kg, naj vzame 25 mg enkrat na dan prvi teden, nato pa poveča dnevni odmerek za 25 mg na začetku vsakega tedna, dokler ni dosežen dnevni odmerek med 150 do 200 mg.
English: Subjects who were seizure-free for 26 weeks at a target dose level continued on this dose for another 26 weeks.
Slovenian: Osebe, ki 26 tednov s ciljnim odmerkom niso imele epileptičnega napada, so s tem odmerkom nadaljevale še 26 tednov.
English: Usual Maintenance Dose
Slovenian: Običajni vzdrževalni odmerek
English: None of these risk factors can reliably predict stone formation during zonisamide treatment.
Slovenian: Noben od teh dejavnikov tveganj ne more zanesljivo napovedati nastanka kamnov med zdravljenjem z zonisamidom.
English: - If you take Zonisamide Mylan twice a day, take half the daily dose in the morning and half in the evening.
Slovenian: - Če jemljete zdravilo Zonisamid Mylan dvakrat na dan, vzemite polovico dnevnega odmerka zjutraj, drugo polovico pa zvečer.
English: You should not stop your treatment without discussing this with your doctor.
Slovenian: Ne prenehajte zdravljenja, ne da bi se pred tem posvetovali z zdravnikom.
English: Zonisamide exposure increases with time until steady state is achieved by approximately 8 weeks.
Slovenian: Izpostavljenost zonisamidu s časom narašča, dokler ni doseženo stanje dinamičnega ravnovesja po približno 8 tednih.
English: All these effects and specifically weight loss may have deleterious implications for growth and development, and may lead to general deterioration of health.
Slovenian: Vsi neželeni učinki, še zlasti izguba telesne mase, imajo lahko škodljiv vpliv na rast in razvoj ter povzročijo splošno krhanje zdravja.