FrancophonIA/ELRC3.0 huggingface dataset:
English: Hypokalaemia, hypomagnesaemia, and hypocalcaemia were observed, usually in association with gastrointestinal disorders and in particular with diarrhoea.
Danish: Hypokaliæmi, hypomagnesiæmi og hypocalcæmi er observeret, sædvanligvis i forbindelse med lidelser i mave-tarmkanalen og især med diarré.
English: For example, a dose of 140 mg docetaxel would require 7 ml docetaxel concentrate for solution.
Danish: For eksempel, en dosis på 140 mg docetaxel vil kræve 7 ml docetaxel koncentrat til infusionsvæske, opløsning.
English: Subset Analyses-Adjuvant Therapy in Patients with Node-negative Breast Cancer Study (Intent-to-Treat Analysis)
Danish: Undergruppeanalyser - adjuverende behandling hos patienter med lymfeknude-negativ brystkræft (intent-to-treat analyse)
English: When patients are candidates for treatment with docetaxel in combination with trastuzumab, they should undergo baseline cardiac assessment.
Danish: Patienter, der er kandidater til behandling med docetaxel i kombination med trastuzumab, bør få foretaget rutinemæssige hjerteundersøgelser.
English: Three docetaxel patients (2%) discontinued the treatment due to fluid retention, whereas 15 doxorubicin patients (9%) discontinued due to cardiac toxicity (three cases of fatal congestive heart failure).
Danish: 3 patienter (2 %), der fik docetaxel, ophørte med behandlingen grundet væskeretention, hvorimod 15 patienter (9 %), der fik doxorubicin, stoppede behandlingen grundet hjertetoksicitet (3 tilfælde af letal hjerteinsufficiens).
English: This may be moderate to severe and has been associated with death (see section 4.8).
Danish: Hjertesvigtet kan være moderat til alvorligt og har været associeret med død (se pkt.
English: In vitro studies have shown that the metabolism of docetaxel may be modified by the concomitant administration of compounds which induce, inhibit or are metabolised by (and thus may inhibit the enzyme competitively) cytochrome P450-3A such as ciclosporine, ketoconazole and erythromycin.
Danish: In vitro-studier har vist, at docetaxels metabolisme kan ændres ved samtidig medicinering med stoffer, som inducerer, hæmmer eller metaboliseres (og således hæmmer enzymet kompetitivt) af cytochrom P450 3A, f.eks ciclosporin, ketoconazol og erythromycin.
English: All patients who did not have progressive disease were to receive CRT as per protocol (PF/CRT).
Danish: Alle patienter uden forværret sygdom skulle ifølge protokollen modtage CRT (PF/CRT).
English: In a pharmacokinetic study with 7 patients, the co-administration of docetaxel with the strong CYP3A4 inhibitor ketoconazole leads to a significant decrease in docetaxel clearance by
Danish: I et farmakokinetisk studie med 7 patienter resulterede samtidig administration af docetaxel og den potente CYP3A4-hæmmer ketoconazol i et signifikant fald i docetaxel-clearance på 49 %.
English: Docetaxel every 3 weeks
Danish: Docetaxel hver 3. uge
English: Patients should not be retreated with subsequent cycles of docetaxel until neutrophils recover to a level >1,500 cells/mm3 and platelets recover to a level >100,000 cells/mm3.
Danish: Patienter bør ikke genbehandles med efterfølgende cyklusser af docetaxel indtil neutrofil-antallet gendannes til et niveau > 1.500 celler/mm3 og blodplader gendannes til et niveau > 100.000 celler/mm3.
English: Clearance of docetaxel in combination therapy with cisplatin was similar to that observed following monotherapy.
Danish: Docetaxels clearence i kombinationsterapi med cisplatin var sammenlignelig med det observerede ved monoterapi.
English: Alopecia; Nail disorders (no severe)
Danish: Alopeci; Neglesygdomme (ikke alvorlig)
English: More than one vial of DOCETAXEL KABI concentrate for solution for infusion may be necessary to obtain the required dose for the patient.
Danish: Mere end 1 hætteglas af DOCETAXEL KABI koncentrat til infusionsvæske, opløsning kan blive nødvendigt for at opnå den påkrævede dosis til patienten.
English: Nervous system
Danish: Nervesystemet
English: The kinetic profile of docetaxel is dose independent and consistent with a three-compartment pharmacokinetic model with half lives for the α, β and γ phases of 4 min, 36 min and 11.1 h, respectively.
Danish: Docetaxels kinetiske profil er dosis-uafhængig og i overensstemmelse med en 3compartment farmakokinetisk model, med halveringstider for α, β og γ faserne på henholdsvis 4 min., 36 min. og 11,1 time.
English: • non-Hodgkin lymphoma (a cancer affecting the immune system) and other cancers may occur in patients who are treated with docetaxel together with certain other anticancer treatments.
Danish: • Non-Hodgkin lymfom (en kræftform, som påvirker immunsystemet) og andre kræftformer kan forekomme hos patienter, der behandles med docetaxel sammen med visse andre behandlinger mod kræft.
English: Survival was superior in the docetaxel + capecitabine combination arm (p = 0.0126).
Danish: Overlevelsen var bedre i kombinationsarmen med docetaxel + capecitabin (p = 0,0126).
English: In combination with trastuzumab the recommended dose of docetaxel is 100 mg/m2 every three weeks, with trastuzumab administered weekly.
Danish: I kombination med trastuzumab er den anbefalede dosis af docetaxel 100 mg/m2 hver 3. uge med en ugentlig administration af trastuzumab.
English: In this study, 501 patients, with locally advanced SCCHN, and a WHO performance status of 0 or 1, were randomised to one of two arms.
Danish: I dette studie blev 501 patienter med lokalt fremskredent SCCHN og en WHO funktionsstatus på 0 eller 1, randomiseret i en af to arme.
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER Fresenius Kabi Deutschland GmbH
Danish: NAVN OG ADRESSE PÅ INDEHAVEREN AF MARKEDSFØRINGSTILLADELSEN Fresenius Kabi Deutschland GmbH
English: Post-Menopausal *a hazard ratio (TAC/FAC) of less than 1 indicates that TAC is associated with a longer disease free survival compared to FAC.
Danish: Post-menopausal * Hazard ratio (TAC/FAC) på mindre end 1 indikerer, at der er en sammenhæng mellem TAC og en længere sygdoms-fri overlevelse, sammenlignet med FAC.
English: The performance status scale, for head and neck (PSS-HN) subscales designed to measure understandability of speech, ability to eat in public, and normalcy of diet, was significantly in favour of TPF as compared to PF.
Danish: Statusskalaen for hoved- og hals underskalaer (PSS-HN) var designet til at måle sprogforståelse, evnen til at indtage føde offentligt samt en normal kost.
English: For the treatment of patients with locally advanced or metastatic breast cancer, the recommended dose of docetaxel is 100 mg/m2 in monotherapy.
Danish: Til behandling af patienter med lokalt fremskreden eller metastatisk brystkræft er den anbefalede dosis docetaxel i monoterapi 100 mg/m2.
English: At the end of chemotherapy, with a minimal interval of 4 weeks and a maximal interval of 7 weeks, patients whose disease did not progress received radiotherapy (RT) according to institutional guidelines for 7 weeks (PF/RT).
Danish: Efter endt kemoterapi, med et minimum interval på 4 uger og et maksimum interval på 7 uger, blev de patienter, hvis sygdom ikke forværredes, strålebehandlet (RT) i 7 uger i henhold til de fastlagte retningslinier (PF/RT).
English: Following the administration of a 100 mg/m2 dose given as a one-hour infusion a mean peak plasma level of 3.7 μg/ml was obtained with a corresponding AUC of 4.6 h.μg/ml.
Danish: Efter administration af docetaxel 100 mg/m2 givet som infusion over 1 time, fandtes den gennemsnitlige maksimale plasmakoncentration at være 3,7 mg/ml med et AUC på 4,6 h.μg/ml.
English: Patients with operable node-negative breast cancer eligible to receive chemotherapy (GEICAM 9805)
Danish: Patienter med operabel, lymfeknude-negativ brystkræft, egnet til behandling med kemoterapi (GEICAM 9805)
English: Efficacy results are presented in the table below:
Danish: Effektresultaterne er vist i tabellen nedenfor:
English: Lacrimation increased
Danish: Forhøjet lakrimation
English: Acute respiratory distress syndrome and cases of interstitial pneumonia/ pneumonitis, interstitial lung disease, pulmonary fibrosis and respiratory failure sometimes fatal have rarely been reported.
Danish: Akut respiratorisk distress syndrom og tilfælde af interstitiel pneumoni/pneumonitis, interstitiel lungesygdom, lungefibrose og respirationssvigt, sommetider letale, er rapporteret sjældent.
English: Previous therapy should have included an anthracycline.
Danish: Tidligere behandling skal have omfattet et anthracyklin
English: • 1,276 patients (744 and 532 in TAX 316 and GEICAM 9805 respectively) who received docetaxel in combination with doxorubicin and cyclophosphamide (clinically important treatment related adverse events are presented).
Danish: • 1.276 patienter (744 i TAX 316 og 532 i GEICAM 9805), som fik docetaxel i kombination med doxorubicin og cyclophosphamid (klinisk vigtige behandlingsrelaterede bivirkninger er nævnt).
English: If the concomitant use of a strong CYP3A4 inhibitor (e.g., ketoconazole, itraconazole, clarithromycin, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin and voriconazole) cannot be avoided, a close clinical surveillance is warranted and a dose-adjustment of docetaxel may be suitable during the treatment with the strong CYP3A4 inhibitor (see section 4.4).
Danish: Hvis samtidig anvendelse af en potent CYP3A4-hæmmer (f.eks. ketoconazol, itraconazol, clarithromycin, indinavir, nefazodon, nelfinavir, ritonavir, saquinavir, telithromycin og voriconazol) ikke kan undgås, er tæt klinisk overvågning nødvendig, og justering af docetaxeldosis kan være hensigtsmæssig under behandling med potente CYP3A4-hæmmere (se pkt.
English: Tell your doctor, hospital pharmacist, or nurse immediately if you have abdominal pain or tenderness, diarrhoea, rectal haemorrhage, blood in stool or fever.
Danish: Kontakt straks lægen, hospitalsfarmaceuten eller sundhedspersonalet, hvis du oplever mavesmerter eller -ømhed, diaré, endetarmsblødning, blodig afførring eller feber.
English: In patients treated with the TAC regimen for node positive breast cancer, the risk of CHF has been shown to be higher during the first year after treatment (see sections 4.8 and 5.1).
Danish: Hos patienter i behandling med TAC-regimet for lymfeknude-positiv brystkræft har risikoen for CHF vist sig at være højere i det første år efter behandling (se pkt.
English: The name of this medicine is DOCETAXEL KABI.
Danish: Medicinen hedder DOCETAXEL KABI.
English: The onset of moderate and severe retention is delayed (median cumulative dose: 818.9 mg/m2) in patients with premedication compared with patients without premedication (median cumulative dose: 489.7 mg/m2); however, it has been reported in some patients during the early courses of therapy.
Danish: Begyndelsen af moderat og alvorlig retention var forsinket hos patienter (median kumulativ dosis: 818,9 mg/m2) med præmedicinering set i forhold til patienter uden præmedicinering (median kumulativ dosis: 489,7 mg/m2).
English: DOCETAXEL KABI must NOT be administered if you are pregnant unless clearly indicated by your doctor.
Danish: DOCETAXEL KABI må IKKE anvendes, hvis du er gravid eller planlægger at blive gravid, medmindre din læge udtrykkelig ønsker det.
English: • Docetaxel 30 mg/m2 administered weekly for the first 5 weeks in a 6 week cycle for 5 cycles.
Danish: • Docetaxel 30 mg/m2 administreret ugentlig i de første 5 uger i en 6 ugers behandlingsrunde i 5 behandlingsrunder.
English: The pharmacokinetic profile of cisplatin administered shortly after docetaxel infusion is similar to that observed with cisplatin alone.
Danish: Cisplatins farmakokinetiske profil, når det administreres kort efter infusion med docetaxel, er sammenlignelig med profilen for cisplatin, når det administreres alene.
English: The most commonly reported adverse reactions of DOCETAXEL KABI alone are: decrease in the number of red blood cells or white blood cells, alopecia, nausea, vomiting, sores in the mouth, diarrhoea and tiredness.
Danish: De mest almindelige bivirkninger af DOCETAXEL KABI givet alene er: Fald i antallet af røde og hvide blodlegemer , hårtab, kvalme, opkastning, sår i munden, diarré og træthed.
English: The cycles were repeated every 3 weeks for 3 cycles.
Danish: Disse cyklusser blev gentaget hver 3. uge i 3 cyklusser.
English: • feeling of numbness or pins and needles or pain in the joints or muscles
Danish: • Følelsesløshed eller stikkende og prikkende fornemmelse eller smerte i led eller muskler
English: In combination with capecitabine
Danish: I kombination med capecitabin
English: Docetaxel is administered as a one-hour infusion every three weeks.
Danish: Docetaxel indgives som en 1-times infusion hver 3. uge.
English: In both arms, after the last cycle of chemotherapy, patients with positive oestrogen and/or progesterone receptors received tamoxifen 20 mg daily for up to 5 years.
Danish: Efter den sidste cyklus af kemoterapi, fik patienter i begge arme, der havde positive østrogen- og/eller progesteronreceptorer tamoxifen 20 mg daglig i op til 5 år.
English: Your doctor should address them immediately.
Danish: Din læge bør straks igangsætte behandling.
English: Heart failure has been observed in patients receiving docetaxel in combination with trastuzumab, particularly following anthracycline (doxorubicin or epirubicin)-containing chemotherapy.
Danish: Hjertesvigt er observeret hos patienter, som fik docetaxel i kombination med trastuzumab, specielt efter kemoterapi med anthracyclin (doxorubicin eller epirubicin).
English: There is no information on the use of docetaxel in pregnant women.
Danish: Der findes ingen data på administration af docetaxel til gravide.
English: PARTICULARS TO APPEAR ON OUTER PACKAGING OUTER CARTON
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE Yderkarton
English: As the benefit observed in patient with 4+ nodes was not statistically significant on disease-free survival (DFS) and overall survival (OS), the positive benefit/risk ratio for TAC in patients with 4+ nodes was not fully demonstrated at the final analysis (see section 5.1).
Danish: Da fordelene hos patienter med 4+ lymfeknuder ikke var statistisk signifikante for sygdoms-fri overlevelse (DFS) og total overlevelse (OS), blev det positive fordel/risiko forhold for TAC-patienter med 4+ lymfeknuder ikke fuldt demonstreret i den endelige analyse (se pkt.
English: There was less use of morphinic analgesic (p < 0.01), non-morphinic analgesics (p < 0.01), other disease-related medicinal products (p = 0.06) and radiotherapy (p < 0.01) in patients treated with docetaxel at 75 mg/m² compared to those with BSC.
Danish: Der var mindre brug af smertestillende morfika (p < 0,01), smertestillende ikke-morfika (p < 0,01), anden ikke-sygdomsrelateret medicin (p = 0,06) og strålebehandling (p < 0,01) hos de patienter, der fik behandling med docetaxel ved doseringen 75 mg/m2 end hos patienterne, der fik bedste palliative behandling.
English: The severity of adverse events of DOCETAXEL KABI may be increased when DOCETAXEL KABI is given in combination with other chemotherapeutic agents.
Danish: Alvorligheden af bivirkningerne ved DOCETAXEL KABI kan forøges, når DOCETAXEL KABI gives i kombination med andre kemoterapeutiske lægemidler.
English: Docetaxel plus trastuzumab was efficacious in patients whether or not they had received prior adjuvant anthracyclines.
Danish: docetaxel + trastuzumab var effektivt til patienterne, uanset om de havde fået adjuverende anthracyclin eller ikke.
English: If DOCETAXEL KABI concentrate or infusion solution should come into contact with skin, wash immediately and thoroughly with soap and water.
Danish: Hvis DOCETAXEL KABI koncentrat eller infusionsvæske skulle komme på huden, så vask omgående og grundigt med sæbe og vand.
English: More grade 3/4 adverse events were observed for docetaxel monotherapy (55.4%) compared to paclitaxel (23.0%).
Danish: Flere grad 3/4 bivirkninger blev observeret for DOCETAXEL KABI monoterapi (55,4 %) sammenlignet med paclitaxel (23,0 %).
English: Primary G-CSF prophylaxis should be considered in patients who receive docetaxel, doxorubicin and cyclophosphamide (TAC) adjuvant therapy for breast cancer.
Danish: Primær G-CSF-profylakse bør overvejes til patienter, som får docetaxel-, doxorubicin- og cyclophosphamid- (TAC)-adjuverende behandling for brystkræft.
English: In study TAX316, 26 patients (3.5%) in the TAC arm and 17 patients (2.3%) in the FAC arm experienced congestive heart failure.
Danish: I studiet TAX 316 oplevede 26 patienter (3,5%) i TAC-armen og 17 patienter (2,3%) i FACarmen kongestivt hjertesvigt.
English: Docetaxel increased response rate (33% vs. 12%, p < 0.0001), prolonged time to progression (19 weeks vs. 11 weeks, p= 0.0004) and prolonged overall survival (11 months vs. 9 months, p= 0.01).
Danish: Docetaxel øgede responsraten (33 % mod 12 %, p < 0,0001), forlængede tiden til progression (19 uger mod 11 uger, p = 0,0004), samt forlængede overlevelsen (11 måneder mod 9 måneder, p = 0,01).
English: The 1-year survival rate was also significantly longer in docetaxel (40%) versus BSC (16%).
Danish: Den 1-årige overlevelsesrate var signifikant længere med docetaxel (40 %) end for bedste palliative behandling (16 %).
English: In particular, please inform your doctor in case of diarrhoea, sores in the mouth, feeling of numbness or pins and needles, fever and give her/him results of your blood tests.
Danish: Vær særlig opmærksom på at informere din læge, hvis du får diarré, sår i munden, følelsesløshed, stikkende og prikkende fornemmelser eller feber, og giv lægen resultatet af dine blodprøver.
English: Severe symptoms such as eruptions followed by desquamation which lead to interruption or discontinuation of docetaxel treatment were reported (see section 4.2).
Danish: Der er rapporteret om alvorlige symptomer såsom udslæt efterfulgt af afskalning, som har ført til afbrydelse eller ophør med docetaxel-behandlingen (se pkt.
English: Previous chemotherapy should have included an anthracycline or an alkylating agent.
Danish: I tidligere kemoterapi skal anthracyclin eller et alkylerende stof have været anvendt.
English: DOCETAXEL KABI in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with:
Danish: DOCETAXEL KABI i kombination med doxorubicin og cyclophosphamid er indiceret til adjuverende behandling af patienter med:
English: From a microbiological point of view, reconstitution/dilution must take place in controlled and aseptic conditions and the medicinal product should be used immediately.
Danish: Fra et mikrobiologisk synspunkt skal rekonstituering/fortynding ske under kontrollerede og aseptiske forhold, og lægemidlet skal anvendes straks.
English: Patients with 4+ nodes
Danish: Patienter med 4+lymfeknuder
English: Both regimens were administered on day 1 every 3 weeks.
Danish: Begge regimer blev indgivet på dag 1 hver 3. uge.
English: Adjuvant therapy for breast cancer
Danish: Adjuverende behandling til brystkræft
English: Consequently, because of the potential for adverse reactions in nursing infants, breast feeding must be discontinued for the duration of docetaxel therapy.
Danish: På grund af risiko for skadelige påvirkninger af barnet skal amning derfor ophøre under behandling med docetaxel.
English: Table below shows that the incidence of Grade 4 neutropenia, febrile neutropenia and neutropenic infection was decreased in patients who received primary G-CSF prophylaxis after it was made mandatory in the TAC arm - GEICAM study.
Danish: Tabellen nedenfor viser, at hyppigheden af grad 4 neutropeni, febril neutropeni og neutropenisk infektion var lavere hos patienter, der fik G-CSF profylaktisk, efter det blev gjort obligatorisk i TAC- armen i GEICAM-studiet.
English: Acute respiratory distress syndrome, interstitial pneumonia/pneumonitis, interstitial lung disease, pulmonary fibrosis and respiratory failure have been reported and may be associated with fatal outcome.
Danish: Akut respiratorisk distress syndrom, interstitiel pneumoni/pneumonitis, interstitiel lungesygdom, lungefibrose og respirationssvigt er blevet rapporteret og kan være associeret med dødelig udgang.
English: The most frequently reported symptoms were flushing, rash with or without pruritus, chest tightness, back pain, dyspnoea and fever or chills.
Danish: De hyppigst rapporterede symptomer var rødme, udslæt med eller uden kløe, trykken for brystet, rygsmerter, dyspnø og feber eller kulderystelser.
English: OTHER SPECIAL WARNING(S), IF NECESSARY Cytotoxic
Danish: EVENTUELLE ANDRE SÆRLIGE ADVARSLER Cytotoksisk
English: Aseptically withdraw the required amount of DOCETAXEL KABI concentrate for solution for infusion using a calibrated syringe.
Danish: Udtrak aseptisk den ønskede mængde af DOCETAXEL KABI koncentrat til infusionsvæske, opløsning ved brug af kalibreret sprøjte.
English: In this study, 358 patients with inoperable locally advanced SCCHN, and WHO performance status 0 or 1, were randomised to one of two treatment arms.
Danish: I denne undersøgelse blev 358 patienter med inoperabelt, lokalt fremskreden SCCHN og WHO funktionsstatus 0 eller 1, randomiseret i en af to behandlingsarme.
English: Without affecting overall survival time (docetaxel 15 months vs. doxorubicin 14 months, p = 0.38) or time to progression (docetaxel 27 weeks vs. doxorubicin 23 weeks, p = 0.54), docetaxel increased response rate (52% vs. 37%, p = 0.01) and shortened time to response (12 weeks vs. 23 weeks, p= 0.007).
Danish: Uden at påvirke overlevelsestiden (docetaxel 15 måneder mod doxorubicin 14 måneder, p = 0,38) eller tiden til progression (docetaxel 27 uger mod doxorubicin 23 uger, p = 0,54), øgede docetaxel responsraten (52 % mod 37 %, p = 0,01) og gav hurtigere respons (12 uger mod 23 uger, p = 0,007).
English: For treatment after failure of prior platinum-based chemotherapy, the recommended dose is 75 mg/m² as a single agent.
Danish: For behandling efter forudgående svigt af platinbaseret kemoterapi, er den anbefalede dosis 75 mg/m2 givet som enkeltstof.
English: If you get any side effects, talk to your doctor, hospital pharmacist or nurse.
Danish: Hvis du oplever bivirkninger, bør du tale med din læge, sygeplejerske eller apoteket.
English: A hazard ratio of less than 1 favours docetaxel + cisplatin + 5-FU *Cox model (adjustment for Primary tumour site, T and N clinical stages and PSWHO) **Logrank test *** Chi-square test
Danish: Med en hazard ratio < 1 kan docetaxel + cisplatin+5-FU anvendes med fordel *Cox model (tilpasning til primær tumor, T og N kliniske stadier og PSWHO) **Logrank test *** Chi-square-test
English: Clinical benefit parameters
Danish: Kliniske fordelsparametre
English: Docetaxel plus trastuzumab1 n = 92
Danish: Docetaxel plus trastuzumab1
English: Second primary malignancies have been reported when docetaxel was given in combination with anticancer treatments known to be associated with second primary malignancies.
Danish: Anden primær malignitet er blevet rapporteret, når docetaxel blev givet i kombination med anticancer behandlinger, der vides at være forbundet med anden primær malignitet.
English: Patients with severe fluid retention such as pleural effusion, pericardial effusion and ascites should be monitored closely.
Danish: Patienter med svær væskeretention i form af pleuraekssudat og perikardieekssudat samt ascites, skal observeres nøje.
English: If subsequent episodes of complicated neutropenia occur the docetaxel dose should be reduced from 60 to 45 mg/m2.
Danish: I tilfælde af efterfølgende episoder med kompliceret neutropeni, bør dosis af docetaxel reduceres fra 60 mg/m2 til 45 mg/m2.
English: Mean values for total body clearance and steady-state volume of distribution were 21 l/h/m2 and 113 l, respectively.
Danish: Gennemsnitsværdierne for den totale clearence og steady-state distributionsvolumen var henholdsvis 21 l/h/m2 og 113 l. Den interindividuelle variation i totalclearance var ca 50 %.
English: In patients treated with docetaxel every three weeks, the incidence of related nail changes occurred at a rate ≥ 10% higher in patients who were 65 years of age or greater compared to younger patients.
Danish: Blandt de patienter, der fik docetaxel hver tredje uge, var hyppigheden af relaterede negleforandringer ≥ 10 % højere i patientgruppen på 65 år og derover, end i gruppen af yngre patienter.