FrancophonIA/ELRC3.0 huggingface dataset:
English: In a clinical study for acute gouty arthritis, patients were treated with etoricoxib 120 mg once daily for eight days.
Danish: I en klinisk undersøgelse for akut arthritis urica blev patienterne behandlet med etoricoxib 120 mg én gang daglig i 8 dage.
English: No clinical data on exposed pregnancies are available for etoricoxib.
Danish: Der foreligger ingen kliniske data om brug af etoricoxib til gravide.
English: As with other drugs known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib.
Danish: Som med andre lægemidler der vides at hæmme prostaglandinsyntesen, er der set væskeretention, ødem og hypertension hos patienter i behandling med etoricoxib.
English: In dogs, renal and gastrointestinal abnormalities were seen at high exposures.
Danish: Ved høje doser er der hos hunde set renale og gastrointestinale abnormiteter.
English: Clinical trials suggest that the selective COX-2 inhibitor class of drugs may be associated with a risk of thrombotic events (especially MI and stroke), relative to placebo and some NSAIDs.
Danish: Kliniske undersøgelser tyder på, at gruppen af selektive COX-2 hæmmere kan være forbundet med en risiko for thrombotiske hændelser (specielt myokardieinfarkt og apopleksi), i forhold til placebo og nogle NSAID.
English: In two 12-week double-blind endoscopy studies, the cumulative incidence of gastroduodenal ulceration was significantly lower in patients treated with etoricoxib 120 mg once daily than in patients treated with either naproxen 500 mg twice daily or ibuprofen 800 mg three times daily.
Danish: I 2, 12-ugers, dobbeltblinde endoskopiundersøgelser, var den kummulative incidens af gastroduodenal ulceration signifikant lavere hos patienter behandlet med etoricoxib 120 mg én gang daglig, end hos patienter behandlet med enten naproxen 500 mg 2 gange daglig eller ibuprofen 800 mg 3 gange daglig.
English: It is not known whether etoricoxib is excreted in human milk.
Danish: Det vides ikke om etoricoxib udskilles i modermælk.
English: Renal insufficiency: The pharmacokinetics of a single dose of etoricoxib 120 mg in patients with moderate to severe renal insufficiency and patients with end-stage renal disease on hemodialysis were not significantly different from those in healthy subjects.
Danish: Farmakokinetikken i forbindelse med enkeltdosis etoricoxib 120 mg hos patienter med moderat til svær nyreinsufficiens og patienter med nyresygdom i terminalt stadie i hæmodialyse, var ikke signifikant forskellig fra den hos raske frivillige.
English: Hormone Replacement Therapy: Administration of etoricoxib 120 mg with hormone replacement therapy consisting of conjugated estrogens (0.625 mg PREMARINTM <or local TRADEMARK>) for 28 days,
Danish: Hormonsubstitutionsbehandling: Anvendelse af etoricoxib 120 mg sammen med hormonsubstitutionsbehandling bestående af konjugerede østrogener (0,625 mg Premarin
English: In patients with moderate hepatic dysfunction (Child-Pugh score 7-9) the recommended dose of 60 mg every other day should not be exceeded.
Danish: Hos patienter med moderat leverdysfunktion (Child-Pugh score 7-9) anbefales at dosis på 60 mg hver anden dag ikke overskrides.
English: Respiratory, thoracic and mediastinal disorders: Uncommon: cough, dyspnoea, epistaxis.
Danish: Respiratoriske lidelser, lidelser i thorax og mediastum: Ikke-almindelig: Hoste, dyspnø, epistaxis.
English: Patients at greatest risk of this response are those with pre-existing significantly impaired renal function, uncompensated heart failure, or cirrhosis.
Danish: Patienter med allerede eksisterende signifikant nedsat nyrefunktion, inkompenseret hjertesvigt eller cirrhose, har størst risiko for dette.
English: Common: gastrointestinal disorders (e.g., abdominal pain, flatulence, heartburn), diarrhea, dyspepsia, epigastric discomfort, nausea.
Danish: Almindelig: Gastrointestinale forstyrrelser (f.eks. mavesmerter, flatulens, halsbrand), diarré, dyspepsi, epigastriske gener, kvalme.
English: The use of etoricoxib, as with any drug substance known to inhibit COX-2, is not recommended in women attempting to conceive.
Danish: Etoricoxib kan, ligesom andre COX-2 hæmmende lægemidler, ikke anbefales til kvinder, der forsøger at blive gravide.
English: In patients experiencing attacks of acute gouty arthritis, etoricoxib 120 mg once daily over an eight-day treatment period, relieved moderate to extreme joint pain and inflammation comparable to indomethacin 50 mg three times daily.
Danish: Hos patienter der oplevede anfald med arthritis urica, lindrede etoricoxib 120 mg én gang daglig over en behandlingsperiode på 8 dage, moderat til ekstrem ledsmerte og inflammation sammenlignet med indomethacin 50 mg 3 gange daglig.
English: A randomized, double-blind, placebo-controlled, parallel-group study evaluated the effects of 15 days of treatment of etoricoxib (90 mg), celecoxib (200 mg bid), naproxen (500 mg bid) and placebo on urinary sodium excretion, blood pressure, and other renal function parameters in subjects 60 to 85 years of age on a 200-mEq/day sodium diet. Etoricoxib, celecoxib, and naproxen had similar effects on urinary sodium excretion over the 2 weeks of treatment.
Danish: En randomiseret, dobbeltblind, placebokontrolleret undersøgelse med parallelle grupper vurderede effekten af 15 dages behandling med etoricoxib (90 mg), celecoxib (200 mg to gange daglig), naproxen (500 mg to gange daglig) og placebo på natriumudskillelsen i urin, blodtryk, og andre nyrefunktionsparametre hos patienter mellem 60 og 85 år, som var på en natriumdiæt på 200 mEq/dag.
English: Etoricoxib is excreted in the milk of lactating rats.
Danish: Etoricoxib udskilles i rottemælk.
English: Etoricoxib 120 mg given with the same oral contraceptive concomitantly or separated by 12 hours, increased the steady state AUC0-24hr of EE by 50 to 60%.
Danish: Etoricoxib 120 mg, som blev givet, enten samtidig med eller 12 timer forskudt, med det samme orale antikonceptionsmiddel, øgede steady-state AUC0-24t af EØ med 5060%.
English: Across clinical pharmacology studies, <INVENTED NAME> produced dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily.
Danish: I alle kliniske, farmakologiske undersøgelser forårsagede <SÆRNAVN>, i doser op til 150 mg daglig, dosisafhængig hæmning af COX-2 uden hæmning af COX-1.
English: Edificio Vasco da Gama, nº19, Porto Salvo 2770-192 Paço d´Arcos Portugal
Danish: Farmacox - Companhia Farmacêutica, Lda Quinta da Fonte, Ed. Vasco da Gama, 19Porto Salvo 2780-730 Paço D'Arcos Portugal
English: The rates of myocardial infarction were 0.68 versus 0.42 events per 100 patient years on etoricoxib and diclofenac respectively.
Danish: Forekomsten af myokardieinfarkt var 0,68 versus 0,42 hændelser pr. 100 patientår for henholdsvis etoricoxib og diclofenac.
English: Immune system disorder: Very rare: hypersensitivity reactions, including angioedema, anaphylactic/anaphylactoid reactions.
Danish: Meget sjælden: Overfølsomhedsreaktioner omfattende angioødem, anafylaktiske/anafylaktoide reaktioner.
English: The following undesirable effects were reported at an incidence greater than placebo in clinical trials in patients with OA, RA or chronic low back pain treated with etoricoxib 60 mg or 90 mg for up to 12 weeks or in post-marketing experience:
Danish: Følgende lægemiddelrelaterede bivirkninger er i kliniske undersøgelser eller efter markedsføring rapporteret med højere incidens end for placebo hos patienter med OA, RA eller kroniske lændesmerter i behandling med etoricoxib 60 mg eller 90 mg i op til 12 uger.
English: Bottles: Keep the container tightly closed.
Danish: Beholder: Opbevares i original emballage tæt tillukket.
English: Common: ALT increased, AST increased.
Danish: Almindelig: Øget ALAT/ASAT.
English: The incidence of congestive heart failure was 0.4% for etoricoxib versus 0.2% for diclofenac.
Danish: Forekomsten af venstresidig hjerteinsufficiens var 0,4% for etoricoxib versus 0,2% for diclofenac.
English: Musculoskeletal, connective tissue and bone disorders: Uncommon: muscular cramp/spasm, musculoskeletal pain/stiffness.
Danish: Muskuloskeletale-, bindevævs- og knoglelidelser: Ikke-almindelig: Muskelkramper/spasmer, smerter/stivhed i bevægeapparatet.
English: There are no clinical or pharmacokinetic data in patients with severe hepatic dysfunction (Child-Pugh score ≥10).
Danish: Der findes ingen kliniske eller farmakokinetiske data fra patienter med svær leverdysfunktion (Child-Pugh score ≥10) (se afsnit 4.2 og 4.3).
English: Nervous system disorder:
Danish: Lidelser i det centrale og perifere nervesystemet:
English: (See sections 4.3 and 4.4.)
Danish: er kontraindiceret (se afsnit 4.3 og 4.4).
English: The effect of etoricoxib on the pharmacokinetics of other drugs
Danish: Effekten af etoricoxib på andre stoffers farmakokinetik
English: Inflammatory bowel disease.
Danish: Inflammatorisk tarmsygdom
English: Uncommon: blood urea nitrogen increased, creatine phosphokinase increased, haematocrit decreased, haemoglobin decreased, hyperkalaemia, leukocytes decreased, platelets decreased, serum creatinine increased, uric acid increased.
Danish: Ikke-almindelig: Øget serum carbamid, øget creatininkinase, fald i hæmatokrit, fald i hæmoglobin, hyperkalæmi, fald i leukocyttal, fald i thrombocyttal, øget serum creatinin, øget urinsyre.
English: Hepatic insufficiency: Patients with mild hepatic dysfunction (Child-Pugh score 5-6) administered etoricoxib 60 mg once daily had an approximately 16% higher mean AUC as compared to healthy subjects given the same regimen.
Danish: Patienter med mild leverdysfunktion (Child-Pugh score 5-6), der fik etoricoxib 60 mg én gang daglig, havde ca. 16% højere middel-AUC end raske frivillige i samme regime.
English: The changes of the Product Information related to the SCAR can be summarised as follows: - Addition of a warning to report that the onset of skin reactions occur in the majority of cases within the first month of treatment.
Danish: Ændringerne i produktinformationen vedrørende SCAR kan sammenfattes således: - tilføjelse af en advarsel med oplysning om, at de fleste tilfælde af hudreaktioner forekommer inden for den første måned af behandlingen, - tilføjelse af en advarsel til patienter med tidligere lægemiddelallergi af enhver art - skærpelse af en advarsel for at fremhæve, at der nu med Cox-2-hæmmere er forekommet alvorlige hudreaktioner med dødelig udgang, - tilføjelse af en mere detaljeret beskrivelse af de første tegn på hudreaktioner, som fører til behandlingsophør.
English: Patients with moderate hepatic dysfunction (Child-Pugh score 7-9) administered etoricoxib 60 mg every other day had similar mean AUC to the healthy subjects given etoricoxib 60 mg once daily.
Danish: Patienter med moderat leverdysfunktion (Child-Pugh score 7-9), der fik etoricoxib 60 mg hver anden dag havde samme middel-AUC som raske frivillige, der fik etoricoxib 60 mg én gang daglig.
English: Invented name
Danish: Sœrnavn
English: Hepatic insufficiency: In patients with mild hepatic dysfunction (Child-Pugh score 5-6) a dose of 60 mg once daily should not be exceeded.
Danish: Hos patienter med mild leverdysfunktion (Child-Pugh score 5-6) bør dosis på 60 mg én gang daglig ikke overskrides.
English: The recommended dose is 120 mg once daily.
Danish: Anbefalet dosis er 120 mg, én gang daglig.
English: 60 mg Tablets: Green, apple-shaped, biconvex tablets <debossed ‘447' on one side and ‘MSD' on the other side>.
Danish: 60 mg tablet: Grøn, æbleformet, bikonveks tablet med ”447” præget på den ene side og ”MSD” på den anden side.
English: However, there was a decrease in embryo/foetal survival at exposures greater than or equal to 1.5 times the human exposure.
Danish: Der var imidlertid et fald i embryo/føtal overlevelse ved doser højere eller svarende til 1,5 gange den daglige humandosis (se afsnit 4.3 og 4.6).
English: Paediatric use: Etoricoxib is contra-indicated in children and adolescents under 16 years of age.
Danish: Børn <SÆRNAVN> er kontraindiceret til børn og unge under 16 år.
English: The recommended dose is 90 mg once daily.
Danish: Anbefalet dosis er 90 mg, én gang daglig.
English: The recommended dose is 60 mg once daily.
Danish: Anbefalet dosis er 60 mg, én gang daglig.
English: COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect.
Danish: På grund af deres manglende antithrombotiske virkning kan selektive COX-2 hæmmere ikke erstatte acetylsalicylsyre som profylakse for kardiovaskulær thromboembolisk sygdom.
English: Uncommon: chest pain.
Danish: Ikke-almindelig: Brystsmerter.
English: Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAIDs and some selective COX-2 inhibitors during post-marketing surveillance (see section 4.8).
Danish: I forbindelse med brugen af NSAID og nogle selektive COX-2 hæmmere er der efter markedsføringen meget sjældent indberettet alvorlige hudreaktioner, nogle af dem fatale, inklusiv exfoliativ dermatitis, Stevens-Johnson syndrom og toksisk epidermisk nekrolyse, (se afsnit 4.8).
English: 90 mg Tablets: White, apple-shaped, biconvex tablets <debossed ‘454' on one side and ‘MSD' on the other side>.
Danish: 90 mg tablet: Hvid, æbleformet, bikonveks tablet med ”454” præget på den ene side og ”MSD” på den anden side.
English: In preclinical studies, etoricoxib has been demonstrated not to be genotoxic.
Danish: Etoricoxib er i prækliniske undersøgelser vist ikke at være genotoksisk.
English: Cardiac disorders: Uncommon: congestive heart failure, non-specific ECG changes, myocardial infarction
Danish: Lidelser i myo-, endo- eller perikardium og klapper: Ikke-almindelig: Venstresidig hjerteinsufficiens, uspecifikke EKG-forandringer, myokardieinfarkt
English: Osteoarthritis
Danish: Osteoarthrose
English: Clinical 1
Danish: Klinisk aspekt 1
English: Hepatic adverse events: Etoricoxib was associated with a statistically significantly lower rate of withdrawals than diclofenac (0.3% versus 5.2%), due largely to elevations in liver function tests.
Danish: Hepatiske hændelser: Etoricoxib var forbundet med en statistisk signifikant lavere forekomst af behandlingsophør på grund af store stigninger i leverfunktionstests end diclofenac (0,3% versus 5,2%).
English: 120 mg Tablets: Pale-green, apple-shaped, biconvex tablets <debossed ‘541' on one side and ‘MSD' on the other side>.
Danish: 120 mg tablet: Lysegrøn, æbleformet, bikonveks tablet med ”541” præget på den ene side og ”MSD” på den anden side.
English: The incidence of patient discontinuations due to oedema was 0.9% for etoricoxib versus 0.7% for diclofenac.
Danish: Forekomsten af behandlingsophør på grund af ødemer var 0,9% for etoricoxib versus 0,7% for diclofenac.
English: The dose for OA should not exceed 60mg daily
Danish: Ved osteoarthrose bør dosis ikke overstige 60 mg dagligt.
English: While knowledge about effects of multiple sulfotransferases is presently limited and the clinical consequences for many drugs are still being examined, it may be prudent to exercise care when administering etoricoxib concurrently with other drugs primarily metabolised by human sulfotransferases (e.g., oral salbutamol and minoxidil).
Danish: Det er vigtigt at udvise forsigtighed når etoricoxib administreres samtidig med andre lægemidler, der metaboliseres primært af humane sulfotransferaser (f.eks. oral salbutamol og minoxidil).
English: Hemodialysis contributed negligibly to elimination (dialysis clearance approximately 50 ml/min).
Danish: Hæmodialysen bidrog i negligiabel grad til eliminiation (dialyseclearance ca. 50 ml/min) (se afsnit 4.3 og 4.4).
English: The main pathway of etoricoxib metabolism is dependent on CYP enzymes.
Danish: Andre lægemidlers effekt på etoricoxibs farmakokinetik: Etoricoxibs primære metaboliseringsvej er afhængig af CYP-enzymer.
English: Clinical 4
Danish: Klinisk aspekt 4
English: Dosing with food (a high-fat meal) had no effect on the extent of absorption of etoricoxib after administration of a 120-mg dose.
Danish: Indtagelse af et måltid (højt fedtindhold) har ikke klinisk betydning for absorptionsgraden af en etoricoxibdosis på 120 mg. Absorptionen påvirkedes, resulterende i et 36% fald i Cmax og en øgning i
English: Clinical 2
Danish: Klinisk aspekt 2
English: General disorders and administration site conditions: Common: asthenia/fatigue, flu-like disease.
Danish: Generelle symptomer og forstyrrelser ved applikationssted: Almindelig: Asteni/træthed, influenzalignende symptomer.
English: Merck sharp & Dohme Ltd. Šmartinska cesta 140 SI-1000 Ljubljana Slovenia
Danish: Merck sharp & Dohme Ltd. Šmartinska cesta 140
English: The dose for RA should not exceed 90mg daily
Danish: Ved rheumatoid arthritis bør dosis ikke overstige 90 mg dagligt.
English: Therefore antiplatelet therapies should not be discontinued (see sections 4.5 and 5.1).
Danish: Kvinder der tager etoricoxib bør ikke amme (se afsnit 4.3 og 5.3).
English: Clinical 3
Danish: Klinisk aspekt 3
English: - Addition of a warning for prescribers to exercise caution when prescribing NSAIDs, in combination with ACE inhibitors or angiotensin II receptor antagonists.
Danish: Hvis blodtrykket stiger betydeligt, bør en alternativ behandling overvejes, - tilføjelse af en advarsel til ordinerende læger om at udvise forsigtighed ved ordinering af NSAID i kombination med ACE-hæmmere eller angiotensin II receptor-antagonister.
English: Tatoiou Street 18 Km Athens-Lamia National Road 14671 Nea Erythrea Athens
Danish: National Road 14671Nea Erythrea, Athens Grækenland
English: The rates of ischemic stroke were 0.14 versus 0.23 per 100 patient years on etoricoxib versus diclofenac respectively.
Danish: Forekomsten af iskæmisk apopleksi var 0,14 versus 0,23 pr. 100 patientår henholdsvis for etoricoxib og diclofenac.
English: Renal and urinary disorders:
Danish: Lidelser i nyrer og urinveje:
English: Uncommon: ecchymosis, facial oedema, pruritus, rash.
Danish: Ikke-almindelig: Ekkymoser, ansigtsødem, pruritus, udslæt.
English: Pharmaceutical Form Route of administration
Danish: Lœgemiddel-form Indgivelses-vej
English: Luxembourg Merck Sharp&Dohme s.a. 1180, Chaussée de Waterloo B-1135 Bruxelles
Danish: Chaussée de Waterloo 1135 B-1180 Bruxelles BELGIEN
English: Merck Sharp & Dohme, Lda Quinta Da Fonte
Danish: Merck Sharp & Dohme, (Portugal) Lda.
English: all available data show an increased risk of CV adverse reactions for Cox-2 inhibitors as a class and agreed that there is an association between duration and dose of intake and the probability of suffering a CV reaction.
Danish: - oplysningerne om lumiracoxib i Target-undersøgelsen, som tyder på en lidt større forekomst af thrombotiske hændelser (navnlig myokardieinfarkt) end for naproxen, at alle foreliggende oplysninger viser øget risiko for kardiovaskulære bivirkninger ved Cox-2hæmmere som lægemiddelklasse, og der var i udvalget enighed om, at der er sammenhæng mellem doseringens varighed og størrelse og sandsynligheden for en kardiovaskulær reaktion.
English: In patients with rheumatoid arthritis (RA), etoricoxib 90 mg once daily provided significant improvements in pain, inflammation, and mobility.
Danish: Den gavnlige effekt blev observeret så tidligt som på anden behandlingsdag og blev opretholdt i op til 52 uger.Hos patienter med rheumatoid arthritis (RA), gav etoricoxib 90 mg én gang daglig signifikant forbedring af smerte, inflammation og mobilitet.
English: Renal prostaglandins may play a compensatory role in the maintenance of renal perfusion.
Danish: Antithrombotisk behandling bør derfor ikke seponeres (se afsnit 4.5 og 5.1).Renal effekt Renale prostaglandiner kan spille en kompensatorisk rolle i opretholdelse af renal perfusion.
English: Concomitant administration of etoricoxib with doses of acetylsalicylic acid above those for cardiovascular prophylaxis or with other NSAIDs is not recommended.
Danish: Samtidig administration af etoricoxib og doser af acetylsalicylsyre, der er højere end de, der anvendes til kardiovaskulær profylakse eller andre NSAID bør undgås (se afsnit 5.1 og 4.4).
English: Common: oedema/fluid retention Uncommon: appetite increase or decrease, weight gain.
Danish: Ikke-almindelig: Ændring af appetit, vægtøgning.
English: United Kingdom Merck Sharp & Dohme Ltd Hertford Road
Danish: Merck, Sharp & Dohme Ltd
English: Via dei Santi Pietro e Paolo, 30 00144 Roma
Danish: Viale Shakespeare, 47 00100 Roma Italien
English: The use of etoricoxib in patients with creatinine clearance <30 ml/min is contraindicated (see sections 4.3 and 4.4).
Danish: Anvendelse af etorixocib til patienter med creatininclearance <30 ml/min.
English: Skin and subcutaneous tissue disorders:
Danish: Vaskulære (ekstrakardielle) lidelser:
English: Bial-Portela & Ca., S.A.
Danish: Laboratórios BIAL-Portela S.A. Av.
English: Merck Sharp E Dohme Italia S.p.A Via G. Fabbroni, 6
Danish: Merck Sharp & Dohme Italia S.p.A.
English: B-1180 Brussels
Danish: SI-1000 Ljubljana Slovenien
English: Vascular disorders:
Danish: Dermatologiske lidelser:
English: MARKETING AUTHORISATION NUMBER To be filled in locally.
Danish: MARKEDSFØRINGSTILLADELSESNUMMER (NUMRE)
English: Merck Sharp & Dohme GmbH Donau-City-Straße 6
Danish: Merck Sharp & Dohme GmbH.
English: Use it as soon as you remember.
Danish: Brug det så snart, som du husker på det.
English: These events are more likely to occur in children.
Danish: Det er mere sandsynligt, at disse hændelser forekommer hos børn.
English: Therefore, it is important that the patient is reviewed regularly.
Danish: Derfor er det vigtigt, at patienten evalueres regelmæssigt.
English: These improvements were statistically significant (p < 0.001).
Danish: Disse forbedringer var statistisk signifikante (p < 0,001).
English: You should clean your inhaler once a week.
Danish: Du bør rengøre din inhalator én gang om ugen.
English: Date of first authorisation: 23 April 2018
Danish: Dato for første markedsføringstilladelse: 23 april 2018
English: Similar improvements, although not statistically significant, were observed at weeks 26 and 52.
Danish: Der blev observeret tilsvarende forbedringer, selvom de ikke var statistisk signifikante, ved uge 26 og 52.
English: Tell your doctor immediately
Danish: Fortæl det straks til lægen
English: IMPORTANT: Do not perform steps 2 to 5 too quickly.
Danish: VIGTIGT: Udfør ikke trin 2 til 5 for hurtigt.
English: ATC code: R03AL09.
Danish: ATC-kode: R03AL09.
English: Other in-use storage times and conditions are under the responsibility of the user.
Danish: Andre opbevaringstider og betingelser under brug er brugerens ansvar.
English: The steps below should be followed.
Danish: De nedenstående trin skal følges.
English: • sleep disorders (sleeping too little or too long)
Danish: • søvnforstyrrelser (for lidt eller for meget søvn)
English: • feeling worried, nervous, over-excited or irritable.
Danish: • bekymret, nervøs, overspændt eller irritabel.
English: Do not give this medicine to children and adolescents below the age of 18 years.
Danish: Dette lægemiddel må ikke gives til børn og unge under 18 år.
English: It is recommended that serum potassium levels are monitored in such situations.
Danish: Det anbefales, at kaliumniveauerne i serum overvåges i sådanne situationer.
English: If your breathing gets worse:
Danish: Hvis din vejrtrækning bliver værre:
English: Component of a multipack, cannot be sold separately.
Danish: Komponent af en multipakning, kan ikke sælges separat.
English: If it is almost time for your next dose, do not take the dose you have missed, but just take the next dose at the correct time.
Danish: Hvis det næsten er tid til din næste dosis, må du ikke tage den glemte dosis, men tag kun den næste dosis på det korrekte tidspunkt.
English: • growth retardation in children and adolescents.
Danish: • væksthæmning hos børn og unge.
English: The two studies included approximately 20% of patients who used the AeroChamber Plus spacer.
Danish: De to studier inkluderede ca. 20 % patienter, der brugte en AeroChamber Plus-spacer.