FrancophonIA/ELRC3.0 huggingface dataset:
English: It works in the same way as aldosterone to retain sufficient water in the body (by retaining sodium and eliminating potassium).
Croatian: Djeluje na isti način kao aldosteron s ciljem zadržavanja dovoljne količine vode u tijelu (tako što zadržava natrij i eliminira kalij).
English: Desoxycortone pivalate
Croatian: Desoksikorton pivalat
English: This medicine may cause pain and swelling at the injection site if accidentally self-administered.
Croatian: Ovaj VMP može uzrokovati bol i oticanje u mjestu injekcije ako se slučajno samoinjektira.
English: Why is Zycortal approved?
Croatian: Zašto je Zycortal odobren?
English: The dose to be given and the interval between treatments depend on the dog's response as well as the blood levels of certain electrolytes (sodium and potassium).
Croatian: Doza koja se primjenjuje i interval između terapija ovisi o odgovoru psa kao i o koncentracijama određenih elektrolita (natrija i kalija) u krvi.
English: The effectiveness of Zycortal was investigated in a field study involving 152 dogs with Addison's disease.
Croatian: Djelotvornost VMP-a Zycortal istražena je u terenskom ispitivanju koje je obuhvatilo 152 psa s Addisonovom bolesti.
English: It is not intended to provide practical advice on how to use Zycortal.
Croatian: Svrha sažetka nije davati praktične savjete o načinu primjene VMP-a Zycortal.
English: Zycortal is a veterinary medicine used to treat dogs with Addison's disease.
Croatian: Zycortal je veterinarsko medicinski proizvod koji se koristi za liječenje pasa s Adisonovom bolesti.
English: Addison's disease is a condition, known as hypoadrenocorticism, where the adrenal glands (located above the kidneys) do not produce enough of two steroid hormones, called cortisol and aldosterone.
Croatian: Addisonova bolest je stanje poznato pod nazivom hipoadrenokorticizam, u slučaju kojeg adrenalne žlijezde (koje se nalaze iznad bubrega) ne proizvode dovoljno steroidnih hormona, naziva kortizol i aldosteron.
English: Zycortal was given by injection under the skin to 113 dogs and 39 dogs were given a similar medicine, which also contains desoxycortone pivalate, for injection into the muscle.
Croatian: Zycortal primijenjen je potkožnom injekcijom u 113 pasa, a 39 pasa primilo je sličan VMP, koji je također sadržavao dezoksikorton pivalat, za injekciju u mišić.
English: What is Zycortal and what is it used for?
Croatian: Što je Zycortal i za što se koristi?
English: This is a summary of the European public assessment report (EPAR) for Zycortal.
Croatian: Ovo je sažetak europskoga javnog izvješća o ocjeni dokumentacije (EPAR) o veterinarsko-medicinskom proizvodu Zycortal.
English: Desoxycortone pivalate is a synthetically produced steroid hormone very similar to the natural hormone aldosterone.
Croatian: Dezoksikorton pivalat je sintetički proizveden steroidni hormon vrlo sličan prirodnom hormonu aldosteronu.
English: Dogs with Addison's disease have insufficient levels of aldosterone in their blood and Zycortal is used to replace the missing hormone.
Croatian: Psi koji boluju od Addisonove bolesti imaju dovoljne količine aldosterona u svojoj krvi, a Zycortal se koristi kao zamjena za hormon koji nedostaje.
English: The Agency's Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Zycortal's benefits are greater than its risks and recommended that it be approved for use in the EU.
Croatian: Odbor za veterinarsko-medicinske proizvode (CVMP) pri Agenciji odlučio je da koristi od VMP-a Zycortal nadmašuju s njim povezane rizike te je preporučio njegovo odobrenje za korištenje u Europskoj uniji.
English: All dogs also received corticosteroids given by mouth.
Croatian: Svi su psi također primili kortikosteroide koji se primjenjuju peroralno.
English: Other information about Zycortal
Croatian: Ostale informacije o VMP-u Zycortal
English: A corticosteroid medicine is likely to be needed, in addition, to replace the cortisol.
Croatian: Izgledno je da su o veterinarsko-medicinski proizvodi koji sadrže kortikosteroid potrebni, između ostalog, za zamjenu kortizola.
English: Zycortal is used long-term to replace the missing aldosterone.
Croatian: Zycortal se koristi kao dugoročna zamjena za smanjivanje aldosterona.
English: Zycortal is available as a prolonged-release suspension for injection.
Croatian: Dostupan je kao suspenzija za injekciju.
English: What are the risks associated with Zycortal?
Croatian: Koji su rizici povezani s VMP-om Zycortal?
English: Zycortal contains the active substance desoxycortone pivalate.
Croatian: Zycortal sadrži djelatnu tvar dezoksikorton pivalat.
English: Zycortal can only be obtained with a prescription.
Croatian: Zycortal se izdaje samo na liječnički recept.
English: 90 days after start of treatment, 84% (92 out of 109) of Zycortal-treated dogs had improved clinical signs and normal sodium and potassium blood levels.
Croatian: U ovom ispitivanju, Zycortal se pokazao barem podjednako djelotvoran kao drugi slični VMP-ovi. 90 dana nakon početka terapije, 84% (92 od 109) pasa liječenih VMP-om Zycortal imalo je poboljšane kliničke znakove i normalne koncentracije natrija i kalija.
English: If irritation occurs, seek medical advice immediately and show the package leaflet or the label to the doctor.
Croatian: Ako nastupi nadraženost, odmah potražite savjet liječnika i pokažite liječniku uputu o VMP-u ili naljepnicu.
English: How does Zycortal work?
Croatian: Kako djeluje Zycortal?
English: The most common side effects with Zycortal (which may affect more than 1 in 10 dogs) are polydipsia (increase in water intake) and polyuria (increase in urine production).
Croatian: Najčešće nuspojave pimobendana (koje se mogu javiti u više od 1 na 10 pasa) povećanje su srčane frekvencije i povraćanje.
English: How is Zycortal used?
Croatian: Kako se Zycortal koristi?
English: What benefits of Zycortal have been shown in studies?
Croatian: Koje su koristi VMP-a Zycortal utvrđene u ispitivanjima?
English: Safety information has been included in the summary of product characteristics and the package leaflet for Zycortal, including the appropriate precautions to be followed by healthcare professionals and animal owners or keepers.
Croatian: U sažetku opisa svojstava VMP-a kao i u uputi o VMP-u Zycortal nalaze se sigurnosne informacije, uključujući odgovarajuće mjere opreza kojih se veterinari te vlasnici životinja ili uzgajivači trebaju pridržavati.
English: For practical information about using Zycortal, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Praktične informacije o primjeni VMP-a Zycortal vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svom veterinaru ili ljekarniku.
English: For more information about treatment with Zycortal, animal owners or keepers should read the package leaflet or contact their veterinarian or pharmacist.
Croatian: Dodatne informacije o terapiji VMP-om Zycortal vlasnici životinja ili uzgajivači trebaju pročitati u uputi o VMP-u, odnosno trebaju se obratiti svojem veterinaru ili ljekarniku.
English: For the full list of all side effects reported with Zycortal, see the package leaflet.
Croatian: Potpuni popis nuspojava zabilježenih pri primjeni VMP-a Zycortal potražite u uputi o VMP-u.
English: The European Commission granted a marketing authorisation valid throughout the EU for Zycortal on
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje je za VMP Zycortal na snazi u Europskoj uniji od 06/11/2015.
English: In the future, if the animals are exposed to this infection, the immune system will be able to respond more quickly.
Croatian: Ubuduće ako se životinje izlože ovoj infekciji, imunosni sustav će brže stvarati protutijela.
English: The European Commission granted a marketing authorisation valid throughout the European Union, for Versican Plus Pi on 4 July 2014.
Croatian: Europska komisija dodijelila je odobrenje za stavljanje u promet koje je na snazi na teritoriju Europske unije za proizvod Versican Plus Pi od 04. srpnja 2014.
English: The dogs were either vaccinated twice with a three to four week interval or they received a single annual booster vaccination.
Croatian: Psi su cijepljeni dva puta u razmaku od tri ili četiri tjedna ili su docijepljeni jednim godišnjim booster cjepivom.
English: For revaccination, a single dose of Versican Plus Pi is required annually.
Croatian: Za docjepljivanje potrebna je jedna doza cjepiva Versican Plus Pi godišnje.
English: This will help protect them against kennel cough.
Croatian: Ovo pomaže pri njihovoj zaštiti od kašlja čopora.
English: The effectiveness of Versican Plus Pi was investigated in a field study involving 129 dogs.
Croatian: Djelotvornost cjepiva Versican Plus Pi ispitana je terenskim ispitivanjem koje je obuhvatilo 129 pasa.
English: The Committee for Medicinal Products for Veterinary Use (CVMP) concluded that the benefits of Versican Plus Pi exceed the risks for the approved indications and recommended that Versican Plus Pi be given a marketing authorisation.
Croatian: Odbor za veterinarsko-medicinske proizvode (CVMP) zaključio je da koristi lijeka Versican Plus Pi nadmašuju rizike za odobrene indikacije i preporučilo je izdavanje odobrenja za stavljanje u promet VMP-a Versican Plus Pi.
English: The field study involved the larger vaccine combinations Versican Plus DHPPi/L4 and Versican Plus DHPPi/L4R, which are also intended to protect against kennel cough in addition to other diseases, to demonstrate effectiveness of Versican Plus Pi.
Croatian: Terensko ispitivanje obuhvatilo je kombinacije većih cjepiva Versican Plus DHPPi/L4 i Versican Plus DHPPi/L4R, čija je namjena također zaštita od kašlja čopora uz ostale bolesti, kako bi se dokazala djelotvornost cjepiva Versican Plus Pi.
English: Other information about Versican Plus Pi:
Croatian: Druge informacije o Versican Plus Pi:
English: The virus in Versican Plus Pi is alive but has been attenuated (weakened) so that does not cause disease.
Croatian: Pseći parainfluenza virus u cjepivu Versican Plus Pi je živ, ali je atenuiran (oslabljen) tako da ne uzrokuje bolest.
English: When Versican Plus Pi is given to dogs, the animals' immune system recognises the viruses as ‘foreign' and makes antibodies against them.
Croatian: U slučaju kada se Versican Plus Pi primjenjuje u pasa, imunosni sustav životinje prepoznaje viruse i bakterije kao prepoznaju viruse kao „strane” i proizvode protutijela
English: Versican Plus Pi is a vaccine.
Croatian: Versican Plus Pi je cjepivo.
English: The most common side effect (seen in more than 1 in 100 dogs) with Versican Plus Pi is a short lived swelling of up to 5 cm which may occur at the injection site after vaccination.
Croatian: Najčešće nuspojave (kod 1 od 100 pasa) lijeka Versican Plus Pi isu kratkotrajno oticanje do 5 cm koje može nastupiti u mjestu injekcije nakon cjepiva.
English: Canine parainfluenza virus vaccine (live attenuated)
Croatian: Virus pseće parainfluence (živi atenuirani)
English: What is the risk associated with Versican Plus Pi?
Croatian: Koji su rizici povezani s Versican Plus Pi?
English: Versican Plus Pi is used to protect dogs against canine parainfluenza virus, which causes kennel cough.
Croatian: Versican Plus Pi se koristi za zaštitu pasa od virusa pseće parainfluenze, koji uzrokuje kašalj čopora.
English: The field study showed that vaccination with Versican Plus Pi resulted in protective levels of antibodies for parainfluenza virus ranging from 73 to 97%.
Croatian: Terenskim je ispitivanjem dokazano da se nakon cijepljenja cjepivom Versican Plus Pi postotak pasa s zaštitnim razinama protutijela za parainfluenza virusa kretao od 73 do 97%.
English: The vaccine is given to puppies from six weeks of age as an injection under the skin which is repeated three to four weeks later.
Croatian: Cjepivo se primjenjuje u štenadi u dobi od osam do devet tjedana u obliku supkutane injekcije i ponavlja se nakon što štenad dosegne starost od dvanaest tjedana.
English: Why has Versican Plus Pi been approved?
Croatian: Zašto je Versican Plus Pi odobren?
English: What benefit has Versican Plus Pi shown during the studies?
Croatian: Koje koristi Versican Plus Pi su utvrđene tijekom ispitivanja?
English: What is Versican Plus Pi?
Croatian: Što je Versican Plus Pi?
English: How has Versican Plus Pi been studied?
Croatian: Kako se Versican Plus Pi ispitivao?
English: What is Versican Plus Pi used for?
Croatian: Za što se Versican Plus Pi koristi?
English: Versican Plus Pi is available as a lyophilisate (freeze-dried pellet) with a solvent that are made up into a suspension for injection.
Croatian: Versican Plus Pi je veterinarsko cjepivo koje sadrži živi atenuirani (oslabljeni) virus pseće parainfluenze tip 2. Versican Plus Pi/L4 dostupan je kao liofilizat (smrzavanjem osušen pelet) s otapalom koji se koriste za pripremu suspenzije za injekciju.
English: How does Versican Plus Pi work?
Croatian: Na koji način Versican Plus Pi djeluje?
English: 180 tablets l t o r
Croatian: 180 tableta k i
English: 800 mg Film-coated tablet Oral use bottle (HDPE)
Croatian: 800 mg Filmom obložena tableta
English: --1 Virus titer no less than of 5 x 107 Inf.U
Croatian: --1 titar virusa nije manji od 5 x 107 Inf.U
English: 20 vials
Croatian: 20 bočice
English: 0.5 ml
Croatian: Bočica (staklo) 0,5 ml
English: Pack size
Croatian: Potkožno
English: Pack size
Croatian: Prašak
English: Immediate Packaging
Croatian: Pomoćne tvari
English: Strength Pharmaceutical Form Route of Administration
Croatian: 14. NAČIN IZDAVANJA LIJEKA
English: 28 vials + 28 prefilled syringes; 6 plungers
Croatian: Tijekom 12 tjedana ispitivane su 3 doze teduglutida: 0,0125 mg/kg/dan (n=8), 0,025 mg/kg/dan
English: Content (concentration)
Croatian: OBLIK I SADRŽAJ
English: 28 vials + 28 prefilled syringes
Croatian: Sadržaj pakiranja: - 28 bočica s 1,25 mg teduglutida u obliku praška - 28 napunjenih štrcaljki s otapalom
English: MA (EU) number (Invented) name
Croatian: DRUGO(A) POSEBNO(A) UPOZORENJE(A), AKO JE POTREBNO
English: 1 vial + 1 prefilled syringe
Croatian: 4.1 Terapijske indikacije
English: The use of protective gloves is recommended.
Croatian: Preporučuje se upotreba zaštitnih rukavica.
English: 29, avenue Tony Garnier FR-69007 Lyon France.
Croatian: 29, avenue Tony Garnier FR-69007 Lyon Francuska.
English: Fipronil: Absolute bioavailability: 9.5 %.
Croatian: Fipronil: apsolutna biodostupnost: 9,5 %.
English: ATCvet code: QP53AX65.
Croatian: ATCvet kôd: QP53AX65.
English: Do not administer orally or via any other route.
Croatian: Ne primjenjivati oralno niti na bilo koji drugi način.
English: Used pipettes should be disposed of immediately.
Croatian: Upotrijebljene pipete treba odmah odstraniti.
English: Do not smoke, drink or eat whilst handling.
Croatian: Pri rukovanju nemojte pušiti, piti ili jesti.
English: Wash hands thoroughly after use.
Croatian: Nakon upotrebe temeljito operite ruke.
English: These measures should help
Croatian: Te mjere pomažu u zaštiti
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 06/05/2011.
Croatian: Datum prvog odobrenja: 06/05/2011.
English: Avoid direct contact with the application site.
Croatian: Izbjegavati izravni kontakt s mjestom primjene.
English: No data available.
Croatian: Podaci nisu dostupni.
English: Children should not be allowed to play with treated dogs until the application site is dry.
Croatian: Djeci se ne smije dopustiti igranje s tretiranim psom sve dok se mjesto primjene ne osuši.
English: In these cases do not treat more frequently than once a fortnight.
Croatian: U takvim slučajevima ne primjenjivati češće nego jednom u dva tjedna.
English: 3 pipettes
Croatian: 3 pipete
English: The CVMP at their meeting on 18 February 2016 decided that one additional five-year renewal was required in view of the outstanding pharmacovigilance data that were undergoing evaluation at the time of the renewal procedure and to ensure that the MAH's pharmacovigilance system is adequate to enable collection and evaluation of adverse events in line with the requirements.
Croatian: CVMP je na sastanku 18. veljače 2016. odlučio da je dodatno petogodišnje produljenje odobrenja za stavljanje u promet potrebno s obzirom na izvanredne farmakovigilancijske podatke koji su bili evaluirani u vrijeme postupaka produljenja odobrenja te da se osigura da je MAH-ov sustav farmakovigilancije primjeren kako bi se omogućilo prikupljanje i procjena nuspojava u skladu sa zahtjevima.
English: For dogs over 60 kg, use the appropriate combination of two pipettes that most closely matches the bodyweight.
Croatian: Za pse teže od 60 kg, upotrijebite odgovarajuću kombinaciju dvije pipete koja najbliže odgovara tjelesnoj masi.
English: Major metabolites are distributed over the entire haircoat of the dog.
Croatian: . Glavni metaboliti raspoređuju se po cijeloj dlaci psa.
English: Dogs should be prevented from accessing streams and rivers for 48-hours following treatment (see section 6.6).
Croatian: Psima treba spriječiti pristup potocima i rijekama 48 sati nakon tretmana (vidjeti odjeljak 6.6).
English: Remove the pipette and hold it upright.
Croatian: Izvadite pipetu držeći ju uspravno.
English: The three active substances are well distributed over the haircoat of the dog during the first week after application.
Croatian: Tri djelatne tvari se dobro raspoređuju po dlaci psa tijekom prvih tjedan dana nakon primjene.
English: Treated animals should not be bathed until 48 hours after treatment.
Croatian: Tretirane životinje se ne smije kupati 48 sati nakon tretmana.
English: In very rare instances, certain sensitive dogs may develop skin irritation at the application site.
Croatian: U rijetkim slučajevima, kod osjetljivih pasa može se pojaviti iritacija kože na mjestu aplikacije.
English: Part the coat until the skin is visible.
Croatian: Razmaknite dlaku da koža bude vidljiva.
English: However, shampooing or immersion of the animal in water directly after treatment or frequent shampooing may reduce the duration of activity.
Croatian: Međutim, pranje šamponom ili uranjanje životinje u vodu neposredno nakon tretmana kao i često pranje šamponom može skratiti trajnost djelovanja.
English: (S)-Methoprene is extensively degraded into carbon dioxide and acetate that are subsequently incorporated into endogenous materials.
Croatian: (S)-Metopren se razgrađuje u ugljični dioksid i acetat koji nakon toga ulaze u endogene materijale.
English: This results in uncontrolled activity of the central nervous system and death of insects or acari.
Croatian: To ima za posljedicu nekontrolirano djelovanje središnjeg živčanog sustava i smrt insekata ili grinja.
English: In case of accidental spillage onto skin, wash off immediately with soap and water.
Croatian: U slučaju nehotičnog prolijevanja na kožu, odmah isperite sapunom i vodom.
English: If it accidentally gets into the eyes, they should be thoroughly flushed with water.
Croatian: Ako slučajno dođe u oči, treba ih temeljito isprati vodom.
English: Volume of unit dose (ml)
Croatian: Količina jedinične doze (ml)
English: Monthly intervals throughout the tick and/or flea seasons, based on local epidemiological situations.
Croatian: Mjesečno tijekom sezone krpelja i/ili buha, ovisno o lokalnim epidemiološkim situacijama.
English: The treated area may appear wet or oily after treatment.
Croatian: Tretirano područje može nakon tretmana izgledati vlažno ili masno.
English: A pharmacokinetic study in dogs, of the active substances alone and in combination, showed that no drug interactions occur between the active substances that affect their pharmacokinetic parameters.
Croatian: Farmakokinetička ispitivanja na psima, samih djelatnih tvari i u kombinaciji, pokazala su da nema interakcija između djelatnih tvari koje bi utjecale na njihove farmakokinetičke parametre.
English: Fipronil sulfone is produced on the haircoat (mean concentrations < 16 % of fipronil during the first month after treatment).
Croatian: Fipronil sulfon se izlučuje na dlaci (prosječne koncentracije < 16 % fipronila tijekom prvih mjesec dana nakon tretmana).
English: Small concentrations of dimethylaniline, a minor degradation product of amitraz, were also observed on the haircoat of the dog post-application but in negligible quantities.
Croatian: Male koncentracije dimetilamina, manji proizvod razgradnje amitraza, također su primijećene na dlaci psa nakon primjene, ali u zanemarivim količinama.
English: This veterinary medicinal product may cause skin sensitisation, allergic reactions and mild eye irritation in humans.
Croatian: Ovaj veterinarsko-medicinski proizvod može izazvati osjetljivost kože, alergijske reakcije i blagu nadraženost očiju u ljudi.
English: Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family.
Croatian: Fipronil je insekticid i akaricid koji pripada obitelji fenilpirazola.
English: A low dose of amitraz together with fipronil has shown synergistic efficacy against ticks resulting in an increased speed of kill (starting at 2 hours and greater than 90 % at 24 hours) and a longer duration of activity when compared to the active substances administered alone.
Croatian: Mala doza amitraza zajedno s fipronilom je pokazala sinergističku djelotvornost u povećanoj brzini ubijanja (počevši od 2 sata i više od 90% za 24 sata) kao i dugotrajnije djelovanje u usporedbi s primjenom
English: For a pack of 3, first separate one blister from the others by tearing along the perforation.
Croatian: U pakovanju od 3 komada, najprije odvojite jedan blister od drugih trgajući po perforaciji.
English: CERTIFECT should not enter water courses as this may be dangerous for fish and aquatic organisms.
Croatian: Certifekt ne smije dospjeti u vodotoke, jer to može biti opasno za ribe i vodene organizme.
English: Animals or persons with a known hypersensitivity to any of the active ingredients or excipients should avoid contact which, on very rare occasions, can cause respiratory irritation and dermal reactions in certain individuals.
Croatian: Životinje i osobe s poznatom preosjetljivošću na bilo koji djelatni sastojak ili pomoćnu tvar trebaju izbjegavati dodir koji, u vrlo rijetkim prilikama, može kod pojedinaca izazvati nadražaj dišnog sustava i reakcije na koži.
English: Other forms of dermatitis including pemphigus-like conditions may occur in even rarer instances.
Croatian: Ostale forme dermatitisa, uključujući pojavu plikova (pemfigus), mogu se javiti u vrlo rijetkim slučajevima.
English: The secondary packaging consists of a plastic/ aluminium blister with a plastic/ aluminium backing.
Croatian: Vanjsko pakovanje je plastično/aluminijski blister s plastično/aluminijskom podlogom.
English: It is therefore recommended that dogs are not treated during the day, but during the early evening, and that recently treated animals are not allowed to sleep with owners, especially children.
Croatian: Stoga se ne preporučuje tretiranje pasa tijekom dana, nego predvečer, te da nedavno tretirane životinje spavaju s vlasnicima, posebno s djecom.
English: Plasma concentrations were below 1 ng/ml (limit of quantification) by approximately 33 days following topical administration.
Croatian: Koncentracije u krvi bile su niže od 1 ng/ml (granica kvantifikacije) za približno 33 dana nakon topikalne primjene.
English: The concentrations of fipronil, fipronil sulfone, amitraz and S-methoprene in the haircoat then decrease with time and are detectable for at least 58 days after dosing.
Croatian: Koncentracije fipronila, fipronil sulfona, amitraza i S-metoprena u dlaci tada s vremenom opadaju i dokazive su najmanje 58 dana nakon primjene
English: For the 2.14 ml, 4.28 ml or 6.42 ml pipette: Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Croatian: Za pipete s 2,14 ml, 4,28 ml ili 6,42 ml: Rok valjanosti veterinarsko-medicinskog proizvoda kad je zapakiran za prodaju: 3 godine.
English: If the dog requires shampooing, it is better to do so before applying the
Croatian: Ako psa treba oprati šamponom, bolje je to učiniti prije primjene veterinarsko-medicinskog proizvoda.
English: Dogs should be prevented from accessing streams and rivers for 48-hours following treatment.
Croatian: Psima treba spriječiti pristup potocima i rijekama 48 sati nakon tretmana.