FrancophonIA/ELRC3.0 huggingface dataset:
English: HIV-1 RNA log10 mean change from baseline (log10 copies/ml) CD4 cell count mean change from baseline (x 10
Slovenian: Srednja vrednost spremembe HIV-1 RNK log10 glede na začetno vrednost (log10 kopij/ml) Srednja vrednost spremembe števila celic CD4 glede na začetno vrednost (x 10
English: AUC ↑ 1.10 (0.94-1.28) Cmax ↑ 1.10 (0.94-1.29) Cmin ↓ 0.88 (0.66-1.17) etravirine
Slovenian: AUC ↑ 1,10 (0,94-1,28) Cmax ↑ 1,10 (0,94-1,29) Cmin ↓ 0,88 (0,66-1,17) etravirin
English: Saquinavir/ritonavir 1,000/100 mg twice daily saquinavir
Slovenian: sakvinavir/ritonavir 1.000/100 mg dvakrat na dan sakvinavir
English: It is not recommended to co-administer INTELENCE with indinavir.
Slovenian: Sočasna uporaba zdravila INTELENCE z indinavirjem ni priporočljiva.
English: Interactions with medicinal products
Slovenian: Medsebojno delovanje z drugimi zdravili
English: Please refer to the product information of the associated boosted PI for the dose adjustment of rifabutin to be used.
Slovenian: Za navodila za prilagajanje odmerka rifabutina, glejte navodila za uporabo sočasno uporabljenega okrepljenega PI.
English: Etravirine 200 mg twice daily postpartum N = 10
Slovenian: 200 mg etravirina dvakrat na dan, po porodu N = 10
English: What INTELENCE looks like and contents of the pack This medicinal product is presented as white to off-white, oval tablet, with “T125” on one side and “100” on the other side.
Slovenian: Izgled zdravila INTELENCE in vsebina pakiranja Bela do belkasta ovalna tableta z oznako “T125” na eni strani in “100” na drugi.
English: Change from baseline in log10 viral load (copies/ml) at week 24, mean (SE) and median (range)
Slovenian: Sprememba log10 virusnega bremena (št. kopij/ml) po 24. tednu (glede na začetek), povprečje (SE) in mediana (razpon)
English: Rash was mostly self-limiting and generally resolved within 1 to 2 weeks on continued therapy.
Slovenian: V večini primerov je bil omejen in je ob nadaljevanju zdravljenja običajno minil v 1 do 2 tednih.
English: INTELENCE has not been studied in patients with severe hepatic impairment (Child-Pugh Class C) and is therefore not recommended (see sections 4.2 and 4.4).
Slovenian: Pri bolnikih s hudo okvaro jeter (razred C po klasifikaciji Child-Pugh) zdravila INTELENCE niso proučevali, zato uporaba zdravila pri njih ni priporočljiva (glejte poglavji 4.2 in 4.4).
English: Each tablet contains 40 mg lactose (as monohydrate).
Slovenian: Ena tableta vsebuje 40 mg laktoze (v obliki monohidrata).
English: Integrase Strand Transfer Inhibitors Dolutegravir
Slovenian: Zaviralci prenosa virusnega genoma s pomočjo encima integraze dolutegravir
English: dolutegravir AUC↔ 1.11(1.02-1.20) Cmin ↑ 1.28 (1.13-1.45) Cmax ↔ 1.07 (1.02-1.13) etravirine
Slovenian: dolutegravir AUC↔ 1,11(1,02-1,20) Cmin ↑ 1,28 (1,13-1,45) Cmax ↔ 1,07 (1,02-1,13) etravirin
English: Hypromellose Microcrystalline cellulose Colloidal anhydrous silica Croscarmellose sodium Magnesium stearate Lactose monohydrate
Slovenian: INTELENCE 100 mg tablete hipromeloza mikrokristalna celuloza koloidni brezvodni silicijev dioksid premreženi natrijev karmelozat magnezijev stearat laktoza monohidrat
English: It is therefore possible that etravirine may inhibit the metabolism of clopidogrel to its active metabolite by such inhibition of CYP2C19 in vivo.
Slovenian: Zato je mogoče, da etravirin z zaviranjem CYP2C19 in vivo zavira presnovo klopidogrela v njegov aktivni presnovek.
English: INTELENCE 100 mg tablets
Slovenian: INTELENCE 100 mg tablete
English: Each tablet contains 160 mg lactose (as monohydrate).
Slovenian: Ena tableta vsebuje 160 mg laktoze (v obliki monohidrata).
English: A plastic bottle containing 60 tablets and 3 pouches to keep the tablets dry.
Slovenian: Plastenka s 60 tabletami in 3 blazinicami s sušilnim sredstvom za tablete.
English: INTELENCE 25 mg tablets
Slovenian: INTELENCE 25 mg tablete
English: INTELENCE 200 mg tablets
Slovenian: INTELENCE 200 mg tablete
English: White to off-white, oval, scored tablet, debossed with “TMC” on one side.
Slovenian: Bela do belkasta ovalna tableta z razdelilno zarezo in vtisnjeno oznako “TMC” na eni strani.
English: AUC ↑ 1.69 (1.53-1.86) Cmin ↑ 1.77 (1.39-2.25) Cmax ↑ 1.62 (1.47-1.79) etravirine
Slovenian: AUC ↑ 1,69 (1,53-1,86) Cmin ↑ 1,77 (1,39-2,25) Cmax ↑ 1,62 (1,47-1,79) etravirin
English: A decreased virologic response to etravirine was observed in patients with viral strains harbouring 3 or more among the following mutations V90I, A98G, L100I, K101E/P, V106I, V179D/F, Y181C/I/V, and G190A/S (see section 5.1).
Slovenian: Pri bolnikih z virusnimi sevi, ki so vsebovali 3 ali več naslednjih mutacij: V90I, A98G, L100I, K101E/P, V106I, V179D/F, Y181C/I/V in G190A/S, so opazili zmanjšan virološki odziv na etravirin (glejte poglavje 5.1).
English: It is part of a treatment reducing the amount of virus in the blood.
Slovenian: Zdravilo INTELENCE ne more ozdraviti okužbe s HIV, ampak sodi v okvir zdravljenja za zmanjševanje količine virusa v krvi.
English: Geometric Mean ± Standard Deviation Median (Range)
Slovenian: AUC12h (ngh/ml) geometrična sredina ± standardna deviacija mediana vrednost (območje) C0h (ng/ml) geometrična sredina ± standardna deviacija mediana vrednost (območje)
English: AUC ↔ 1.06 (0.99-1.14) Cmin ↔ 1.08 (0.98-1.19) Cmax ↔ 1.05 (0.95-1.17) maraviroc*
Slovenian: AUC ↔ 1,06 (0,99-1,14) Cmin ↔ 1,08 (0,98-1,19) Cmax ↔ 1,05 (0,95-1,17) maravirok*
English: The bottle is a high-density polyethylene (HDPE) plastic bottle containing 60 tablets and 3 desiccant pouches, fitted with a polypropylene (PP) child resistant closure.
Slovenian: Plastenka iz polietilena velike gostote (HDPE) vsebuje 60 tablet, 3 blazinice s sušilnim sredstvom in je opremljena s polipropilensko (PP) zaporko, varno za otroke.
English: No interaction is expected for either INTELENCE or enfuvirtide when co-administered.
Slovenian: Pri sočasni uporabi zdravila INTELENCE in enfuvirtida ni pričakovati medsebojnih delovanj.
English: AUC ↔ 0.87 (0.83-0.92) Cmin ↓ 0.80 (0.73-0.88) Cmax ↔ 0.89 (0.82-0.96) etravirine
Slovenian: AUC ↔ 0,87 (0,83-0,92) Cmin ↓ 0,80 (0,73-0,88) Cmax ↔ 0,89 (0,82-0,96) etravirin
English: AUC12h (ng•h/ml) Geometric Mean ± Standard Deviation Median (Range) C0h (ng/ml) Geometric Mean ± Standard Deviation Median (Range) * All HIV-1 infected subjects enrolled in Phase III clinical trials received darunavir/ritonavir 600/100 mg twice daily as part of their background regimen.
Slovenian: * Vsi s HIV-1 okuženi preskušanci vključeni v klinična preskušanja III. faze so kot del osnovne sheme zdravljenja prejeli darunavir/ritonavir 600/100 mg dvakrat na dan.
English: HIV PIs - Boosted with cobicistat Atazanavir/cobicistat Darunavir/cobicistat
Slovenian: HIV PI (zaviralci proteaze) - okrepljeni s kobicistatom atazanavir/kobicistat darunavir/kobicistat
English: AUC ↑ 1.18 (1.03-1.36) Cmin ↑ 1.24 (0.96-1.59) Cmax ↑ 1.14 (1.02-1.27) etravirine
Slovenian: AUC ↑ 1,18 (1,03-1,36) Cmin ↑ 1,24 (0,96-1,59) Cmax ↑ 1,14 (1,02-1,27) etravirin
English: The bottle is a high-density polyethylene (HDPE) plastic bottle containing 120 tablets and 2 desiccant pouches, fitted with a polypropylene (PP) child resistant closure.
Slovenian: Plastenka iz polietilena velike gostote (HDPE) vsebuje 120 tablet, 2 blazinici s sušilnim sredstvom in je opremljena s polipropilensko (PP) zaporko, varno za otroke.
English: INTELENCE and raltegravir can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in raltegravir se lahko uporabljata brez prilagajanja odmerkov.
English: Tablet White to off-white, oval tablet debossed with “T125” on one side and “100” on the other side.
Slovenian: INTELENCE 100 mg tablete tableta Bela do belkasta ovalna tableta z vtisnjeno oznako “T125” na eni strani in “100” na drugi.
English: INTELENCE and atazanavir/ritonavir can be used without dose adjustment.
Slovenian: Zdravilo INTELENCE in kombinacija atazanavir/ritonavir se lahko uporabljajo brez prilagajanja odmerkov.
English: HIV Protease Inhibitors (PIs) - Unboosted (i.e. without co-administration of low-dose ritonavir) Indinavir
Slovenian: HIV PI (zaviralci proteaze) - neokrepljeni (t.j.
English: A plastic bottle containing 120 tablets and 2 pouches to keep the tablets dry.
Slovenian: Plastenka s 120 tabletami in 2 blazinicama s sušilnim sredstvom za tablete.
English: Etravirine is expected to increase plasma concentrations of diazepam.
Slovenian: Pričakovati je, da etravirin zviša plazemsko koncentracijo diazepama.
English: AUC ↔ 1.15 (1.05-1.26) Cmin ↔ 1.02 (0.90-1.17) Cmax ↔ 1.11 (1.01-1.22) etravirine
Slovenian: AUC ↔ 1,15 (1,05-1,26) Cmin ↔ 1,02 (0,90-1,17) Cmax ↔ 1,11 (1,01-1,22) etravirin
English: amnesia, somnolence uncommon convulsion, syncope, tremor, hypersomnia, disturbance in attention
Slovenian: Bolezni živčevja zelo pogosti glavobol pogosti periferna nevropatija, parestezije, hipestezija, amnezija, somnolenca občasni konvulzije, sinkopa, tremor, hipersomnija, motnje pozornosti
English: INTELENCE 25 mg tablets etravirine
Slovenian: INTELENCE 25 mg tablete etravirin
English: Combination not recommended.
Slovenian: Sočasna uporaba ni priporočljiva.
English: AUC ↔ 0.94 (0.88-1.01) Cmin ↔ 0.91 (0.84-0.98) Cmax ↔ 0.92 (0.85-1.00) etravirine
Slovenian: AUC ↔ 0,94 (0,88-1,01) Cmin ↔ 0,91 (0,84-0,98) Cmax ↔ 0,92 (0,85-1,00) etravirin
English: AUC ↔ 1.15 (1.09-1.21) Cmin ↑ 1.19 (1.13-1.26) Cmax ↑ 1.15 (1.04-1.27) etravirine
Slovenian: AUC ↔ 1,15 (1,09-1,21) Cmin ↑ 1,19 (1,13-1,26) Cmax ↑ 1,15 (1,04-1,27) etravirin
English: INTELENCE and these antifungals can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in navedeni antimikotiki se lahko uporabljajo brez prilagajanja odmerkov.
English: INTELENCE and didanosine can be used without dose adjustments.
Slovenian: INTELENCE in didanozin se lahko uporabljata brez prilagajanja odmerkov.
English: Renal and urinary disorders common renal failure, blood creatinine increased
Slovenian: Bolezni sečil pogosti ledvična odpoved, zvečanje koncentracije kreatinina v krvi
English: INTELENCE can be co-administered with proton pump inhibitors without dose adjustments.
Slovenian: Zdravilo INTELENCE lahko uporabljate sočasno z zaviralci protonske črpalke brez prilagoditve odmerka.
English: 0.035 mg once daily
Slovenian: 0,035 mg enkrat na dan noretisteron
English: Each tablet contains 25 mg etravirine.
Slovenian: Ena tableta vsebuje 25 mg etravirina.
English: The bottle is a high-density polyethylene (HDPE) plastic bottle containing 120 tablets and 3 desiccant pouches, fitted with a polypropylene (PP) child resistant closure.
Slovenian: Plastenka iz polietilena velike gostote (HDPE) vsebuje 120 tablet, 3 blazinice s sušilnim sredstvom in je opremljena s polipropilensko (PP) zaporko, varno za otroke.
English: INTELENCE and fluconazole can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in flukonazol se lahko uporabljata brez prilagajanja odmerkov.
English: AUC ↓ 0.62 (0.48-0.80) Cmin ↓ 0.82 (0.67-1.01) Cmax ↓ 0.72 (0.55-0.94) dihydroartemisinin AUC ↓ 0.85 (0.75-0.97) Cmin ↓ 0.83 (0.71-0.97) Cmax ↓ 0.84 (0.71-0.99) lumefantrine AUC ↓ 0.87 (0.77-0.98) Cmin ↔ 0.97 (0.83-1.15) Cmax ↔ 1.07 (0.94-1.23) etravirine
Slovenian: AUC ↓ 0,62 (0,48-0,80) Cmin ↓ 0,82 (0,67-1,01) Cmax ↓ 0,72 (0,55-0,94) dihidroartemisinin AUC ↓ 0,85 (0,75-0,97) Cmin ↓ 0,83 (0,71-0,97) Cmax ↓ 0,84 (0,71-0,99) lumefantrin
English: AUC ↓ 0.47 (0.38-0.58) Cmin ↓ 0.61 (0.53-0.71) Cmax ↓ 0.40 (0.28-0.57) etravirine
Slovenian: AUC ↓ 0,47 (0,38-0,58) Cmin ↓ 0,61 (0,53-0,71) Cmax ↓ 0,40 (0,28-0,57) etravirin
English: AUC ↓ 0.83 (0.75-0.94) Cmin ↓ 0.76 (0.66-0.87) Cmax ↓ 0.90 (0.78-1.03) 25-O-desacetyl-rifabutin AUC ↓ 0.83 (0.74-0.92) Cmin ↓ 0.78 (0.70-0.87) Cmax ↓ 0.85 (0.72-1.00) etravirine
Slovenian: AUC ↓ 0,83 (0,75-0,94) Cmin ↓ 0,76 (0,66-0,87) Cmax ↓ 0,90 (0,78-1,03) 25-O-deacetil-rifabutin AUC ↓ 0,83 (0,74-0,92) Cmin ↓ 0,78 (0,70-0,87) Cmax ↓ 0,85 (0,72-1,00) etravirin
English: AUC ↔ 0.95 (0.64-1.42) Cmin ↓ 0.80 (0.46-1.38) Cmax ↔ 1.00 (0.70-1.42) etravirine
Slovenian: AUC ↔ 0,95 (0,64-1,42) Cmin ↓ 0,80 (0,46-1,38) Cmax ↔ 1,00 (0,70-1,42) etravirin
English: Parameter
Slovenian: Presnovni parametri
English: dolutegravir AUC↓ 0.75 (0.69-0.81) Cmin ↓ 0.63 (0.52-0.77) Cmax ↓ 0.88 (0.78-1.00) etravirine
Slovenian: dolutegravir AUC↓ 0,75 (0,69-0,81) Cmin ↓ 0,63 (0,52-0,77) Cmax ↓ 0,88 (0,78-1,00) etravirin
English: Etravirine is expected to increase plasma concentrations of warfarin.
Slovenian: Pričakovati je, da etravirin zviša plazemsko koncentracijo varfarina.
English: A plastic bottle containing 120 tablets and 3 pouches to keep the tablets dry.
Slovenian: Plastenka s 120 tabletami in 3 blazinicami s sušilnim sredstvom za tablete.
English: No dose adjustment is suggested in patients with mild or moderate hepatic impairment (Child-Pugh Class A or B); INTELENCE should be used with caution in patients with moderate hepatic impairment.
Slovenian: Pri bolnikih z blago do zmerno okvaro jeter (razred A ali B po klasifikaciji Child-Pugh) ni potrebno prilagajati odmerka.
English: INTELENCE 100 mg tablets etravirine
Slovenian: INTELENCE 100 mg tablete etravirin
English: Common side effects (may affect up to 1 in 10 people) - allergic reactions (hypersensitivity); - diabetes, decrease of appetite; - anxiety, sleepiness, sleeplessness, sleep disorders; - tingling or pain in hands or feet, numbness, loss of skin sensibility, loss of memory tiredness; - blurred vision; - kidney failure, high blood pressure, heart attack, shortness of breath when exercising; - vomiting, heartburn, abdominal pain, distension of the abdomen, inflammation of the stomach,
Slovenian: Pogosti neželeni učinki (pojavijo se pri največ 1 od 10 bolnikov) - alergijske reakcije (preobčutljivost) - sladkorna bolezen, zmanjšan apetit - tesnoba, zaspanost, nespečnost, motnje spanja - mravljinci ali bolečine v dlaneh in stopalih, občutek odrevenelosti, izguba občutljivosti kože,
English: Even if you feel better, do not stop taking INTELENCE or your other anti-HIV medicines.
Slovenian: Med zdravljenjem okužbe z virusom HIV se boste lahko začeli počutiti bolje, vendar kljub temu ne smete prenehati z jemanjem zdravila INTELENCE in drugih zdravil proti temu virusu, ker bi lahko s tem povečali tveganje za razvoj odpornosti virusa na zdravilo.
English: INTELENCE and azithromycin can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in azitromicin se lahko uporabljata brez prilagajanja odmerkov.
English: What INTELENCE looks like and contents of the pack This medicinal product is presented as white to off-white, oval, scored tablet, with “TMC” on one side.
Slovenian: Izgled zdravila INTELENCE in vsebina pakiranja Bela do belkasta ovalna tableta, z razdelilno zarezo in oznako “TMC” na eni strani.
English: Each tablet of INTELENCE contains 25 mg of etravirine.
Slovenian: Ena tableta zdravila INTELENCE vsebuje 25 mg etravirina.
English: INTELENCE 200 mg tablets etravirine
Slovenian: INTELENCE 200 mg tablete etravirin
English: Swallow the INTELENCE tablet(s) whole with a glass of water.
Slovenian: Tableto (tablete) zdravila INTELENCE morate pogoltniti celo (cele) s kozarcem vode in je (jih) ne smete žvečiti.
English: Each tablet contains 100 mg etravirine.
Slovenian: Ena tableta vsebuje 100 mg etravirina.
English: Each tablet contains 200 mg etravirine.
Slovenian: Ena tableta vsebuje 200 mg etravirina.
English: Etravirine is expected to increase nelfinavir plasma concentrations.
Slovenian: Pričakovati je, da etravirin zviša plazemske koncentracije nelfinavirja.
English: AUC ↓ 0.90 (0.68-1.18) Cmin ↓ 0.66 (0.34-1.26) Cmax ↓ 0.89 (0.68-1.15) etravirine
Slovenian: AUC ↓ 0,90 (0,68-1,18) Cmin ↓ 0,66 (0,34-1,26) Cmax ↓ 0,89 (0,68-1,15) etravirin
English: AUC ↔ 1.03 (0.90-1.18) Cmin ↓ 0.87 (0.75-1.02) Cmax ↔ 1.06 (0.95-1.20) etravirine
Slovenian: AUC ↔ 1,03 (0,90-1,18) Cmin ↓ 0,87 (0,75-1,02) Cmax ↔ 1,06 (0,95-1,20) etravirin
English: NNRTIs Efavirenz Nevirapine Rilpivirine
Slovenian: NNRTI (nenukleozidni zaviralci reverzne transkriptaze) efavirenz nevirapin rilpivirin
English: Each tablet of INTELENCE contains 100 mg of etravirine.
Slovenian: Ena tableta zdravila INTELENCE vsebuje 100 mg etravirina.
English: 200 mg twice daily eight 25 mg tablets twice daily or two 100 mg tablets twice daily or one 200 mg tablet twice daily
Slovenian: 200 mg dvakrat na dan osem 25 mg tablet dvakrat na dan ali dve 100 mg tableti dvakrat na dan ali ena 200 mg tableta dvakrat na dan
English: What INTELENCE looks like and contents of the pack This medicinal product is presented as white to off-white, biconvex, oblong tablet with “T200” on one side.
Slovenian: Izgled zdravila INTELENCE in vsebina pakiranja Bela do belkasta, bikonveksna, podolgovata tableta z oznako “T200” na eni strani.
English: Fusion Inhibitors Enfuvirtide 90 mg twice daily etravirine*
Slovenian: 90 mg dvakrat na dan etravirin*
English: Proportion of subjects with HIV-1 RNA < 50 copies/ml at week 48
Slovenian: Odstotek preiskovancev s HIV-1 RNK < 50 kopij/ml v 48. tednu etravirin + BR N = 599
English: Norethindrone
Slovenian: didanozin
English: In the morning, take two 100 milligram INTELENCE tablets, following a meal.
Slovenian: Zjutraj vzemite dve 100 miligramski tableti zdravila INTELENCE po jedi.
English: Most often, rash was mild to moderate, of macular/papular type, and occurred in the second week of therapy.
Slovenian: Izpuščaj se je najpogosteje pojavil v drugem tednu zdravljenja, bil je blag, makularno /papilarenega tipa.
English: Each tablet of INTELENCE contains 200 mg of etravirine.
Slovenian: Ena tableta zdravila INTELENCE vsebuje 200 mg etravirina.
English: All ranges * Etravirine RAMs = V90I, A98G, L100I, K101E/P, V106I, V179D/F, Y181C/I/V, G190A/S
Slovenian: * RAMi etravirina = V90I, A98G, L100I, K101E/P, V106I, V179D/F, Y181C/I/V, G190A/S Opomba: Vsi bolniki iz preskušanj DUET so prejemali osnovno shemo: darunavir/ritonavir, NRTI po izbiri raziskovalca in enfuvirtid po izbiri.
English: Silicified microcrystalline cellulose Microcrystalline cellulose Colloidal anhydrous silica Croscarmellose sodium Magnesium stearate
Slovenian: INTELENCE 200 mg tablete hipromeloza silicirana mikrokristalna celuloza mikrokristalna celuloza koloidni brezvodni silicijev dioksid premreženi natrijev karmelozat magnezijev stearat
English: (Hypericum perforatum)
Slovenian: ZDRAVILA RASTLINSKEGA IZVORA Šentjanževka (Hypericum perforatum)
English: Severe cutaneous adverse reactions have been reported with etravirine.
Slovenian: Pri uporabi etravirina so poročali tudi o hudih kožnih neželenih reakcijah.
English: AUC ↓ 0.86 (0.79-0.93) Cmin ↓ 0.62 (0.55-0.71) Cmax ↔ 0.97 (0.89-1.05) etravirine
Slovenian: AUC ↓ 0,86 (0,79-0,93) Cmin ↓ 0,62 (0,55-0,71) Cmax ↔ 0,97 (0,89-1,05) etravirin
English: INTELENCE and lopinavir/ritonavir can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in kombinacija lopinavir/ritonavir se lahko uporabljajo brez prilagajanja odmerkov.
English: 125 mg twice daily five 25 mg tablets twice daily or one 100 mg tablet and one 25 mg tablet twice daily
Slovenian: ≥ 20 do < 25 kg 125 mg dvakrat na dan pet 25 mg tablet dvakrat na dan ali ena 100 mg tableta in ena 25 mg tableta dvakrat na dan
English: The combination of INTELENCE and ribavirin can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in ribavirin se lahko uporabljata brez prilagajanja odmerkov.
English: No data other than drug-drug interaction data (see section 4.5) are available when etravirine is combined with raltegravir or maraviroc.
Slovenian: Podatki o kombiniranju etravirina z raltegravirjem ali maravirokom niso na voljo, razen tistih, ki zadevajo medsebojno delovanje zdravil (glejte poglavje 4.5).
English: It is recommended that the international normalised ratio (INR) be monitored when warfarin is combined with INTELENCE.
Slovenian: Pri kombiniranju varfarina z zdravilom INTELENCE je priporočljivo, da spremljate protrombinski čas (INR).
English: Nederland Janssen-Cilag B.V. Tel: +31 76 711 1111 janssen@jacnl.jnj.com
Slovenian: Tel: +31 76 711 1111 janssen@jacnl.jnj.com
English: The bottle contains 2 little pouches (desiccants) to keep the tablets dry.
Slovenian: Plastenka vsebuje tudi 2 majhni blazinici (sušilno sredstvo za sušenje tablet), ki morata ostati v plastenki ves čas in ju ne smete zaužiti.
English: 150 mg twice daily six 25 mg tablets twice daily or one 100 mg tablet and two 25 mg tablets twice daily
Slovenian: ≥ 25 do < 30 kg 150 mg dvakrat na dan šest 25 mg tablet dvakrat na dan ali ena 100 mg tableta in dve 25 mg tableti dvakrat na dan
English: Using the oral solution may be considered for dose reduction.
Slovenian: Pri prilagajanju odmerka si lahko pomagate z uporabo peroralne raztopine.
English: If a rash occurs, it usually appears soon after anti-HIV treatment with INTELENCE is started and often disappears within 1 to 2 weeks, even with continued use of the medicine.
Slovenian: Pogosto tak izpuščaj izgine v 1 do 2 tednih kljub nadaljnji uporabi zdravila.
English: INTELENCE and digoxin can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in digoksin lahko uporabljate brez prilagoditve odmerka.
English: In the evening, take two 100 milligram INTELENCE tablets, following a meal.
Slovenian: Zvečer vzemite dve 100 miligramski tableti zdravila INTELENCE po jedi.
English: INTELENCE can be co-administered with paroxetine without dose adjustments.
Slovenian: Zdravilo INTELENCE lahko uporabljate sočasno s paroksetinom brez prilagoditve odmerka.
English: Tablet White to off-white, biconvex, oblong tablet debossed with “T200” on one side.
Slovenian: INTELENCE 200 mg tablete tableta Bela do belkasta bikonveksna ovalna tableta z vtisnjeno oznako “T200” na eni strani.
English: Fosamprenavir/ritonavir 700/100 mg twice daily amprenavir
Slovenian: 700/100 mg dvakrat na dan amprenavir
English: The bottle contains 3 little pouches (desiccants) to keep the tablets dry.
Slovenian: Plastenka vsebuje tudi 3 majhne blazinice (sušilno sredstvo za sušenje tablet), ki morajo ostati v plastenki ves čas in jih ne smete zaužiti.
English: INTELENCE and saquinavir/ritonavir can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in kombinacija sakvinavir/ritonavir se lahko uporabljajo brez prilagajanja odmerkov.
English: Co-administration of Intelence and daclatasvir is not recommended.
Slovenian: Sočasna uporaba zdravila INTELENCE in daklatasvirja ni priporočljiva.
English: Etravirine 200 mg twice daily 2
Slovenian: vorikonazol 200 mg dvakrat na dan vorikonazol
English: Co-administration of etravirine with daclatasvir may decrease daclatasvir concentrations.
Slovenian: Sočasna uporaba etravirina in daklatasvirja lahko zmanjša koncentracije daklatasvirja.
English: Eye disorders common blurred vision
Slovenian: Očesne bolezni občasni zamegljen vid
English: 1 mg once daily ethinylestradiol AUC ↑ 1.22 (1.13-1.31) Cmin ↔ 1.09 (1.01-1.18) Cmax ↑ 1.33 (1.21-1.46) norethindrone AUC ↔ 0.95 (0.90-0.99) Cmin ↓ 0.78 (0.68-0.90) Cmax ↔ 1.05 (0.98-1.12) etravirine
Slovenian: 1 mg enkrat na dan etinilestradiol AUC ↑ 1,22 (1,13-1,31) Cmin ↔ 1,09 (1,01-1,18) Cmax ↑ 1,33 (1,21-1,46) noretisteron
English: Dexamethasone is expected to decrease plasma concentrations of etravirine
Slovenian: Pričakovati je, da pri sočasni uporabi deksametazon zniža plazemsko koncentracijo etravirina.
English: In the morning, take one 200 milligram INTELENCE tablet, following a meal.
Slovenian: Zjutraj vzemite eno 200 miligramsko tableto zdravila INTELENCE po jedi.
English: CCR5 Antagonists Maraviroc 300 mg twice daily
Slovenian: Antagonisti CCR5 maravirok
English: INTELENCE and voriconazole can be used without dose adjustments.
Slovenian: Zdravilo INTELENCE in vorikonazol se lahko uporabljata brez prilagajanja odmerkov.
English: Baseline characteristics Median plasma HIV-1 RNA 4.8 log10copies/ml
Slovenian: Začetne značilnosti Mediana vrednost HIV-1 RNK v plazmi
English: In the evening, take one 200 milligram INTELENCE tablet, following a meal.
Slovenian: Zvečer vzemite eno 200 miligramsko tableto zdravila INTELENCE po jedi.
English: Voriconazole 200 mg twice daily voriconazole AUC ↑ 1.14 (0.88-1.47) Cmin ↑ 1.23 (0.87-1.75) Cmax ↓ 0.95 (0.75-1.21) etravirine
Slovenian: AUC ↑ 1,14 (0,88-1,47) Cmin ↑ 1,23 (0,87-1,75) Cmax ↓ 0,95 (0,75-1,21) etravirin
English: Etravirine 200 mg twice daily N = 575
Slovenian: 200 mg etravirina dvakrat na dan, drugo trimesečje N = 13
English: Tablet
Slovenian: Odmerjanje