FrancophonIA/ELRC3.0 huggingface dataset:
English: The dosage of other medicines might need to be changed since either their own or PREZISTA's therapeutic effect or side effects may be influenced when combined.
Croatian: Postoji mogućnost da će biti potrebno promijeniti doziranje drugih lijekova, s obzirom na mogućnost promjene terapijskog učinka ili nuspojava tih lijekova ili lijeka PREZISTA kada se primjenjuju u kombinaciji.
English: Systemic corticosteroid effects including Cushing's syndrome and adrenal suppression have been reported in patients receiving ritonavir and inhaled or intranasally administered fluticasone.
Croatian: Sistemski učinci kortikosteroida uključujući Cushingov sindrom i adrenalnu supresiju bili su prijavljeni kod bolesnika koji su primali ritonavir i inhalirani ili intranazalno primijenili flutikazon.
English: Twice daily dosing Weight
Croatian: Doziranje dva puta na dan Težina
English: PREZISTA/ritonavir should not be used in children below 3 years of age because of safety concerns (see sections 4.4 and 5.3).
Croatian: PREZISTA/ritonavir se ne smiju primjenjivati u djece uzrasta ispod 3 godine zbog sigurnosnih razloga (vidjeti dijelove 4.4 i 5.3).
English: PREZISTA oral suspension contains sodium methyl parahydroxybenzoate (E219) which may cause allergic reactions (possibly delayed).
Croatian: PREZISTA oralna suspenzija sadrži natrijev metilparahidroksibenzoat (E219) koji može uzrokovati alergijske reakcije (mogu biti odgođene).
English: Fluticasone: in a clinical study where ritonavir 100 mg capsules twice daily were co-administered with 50 g intranasal fluticasone propionate (4 times daily) for 7 days in healthy subjects, fluticasone propionate plasma concentrations increased significantly, whereas the intrinsic cortisol levels decreased by approximately 86% (90% CI 82-89%).
Croatian: Flutikazon: u kliničkom ispitivanju gdje su ritonavir 100 mg kapsule dva puta na dan istodobno primijenjene s 50 g intranazalnog flutikazon propionata (4 puta na dan) tijekom 7 dana kod zdravih ispitanika, značajno su porasle koncentracije flutikazon propionata u plazmi, dok su se razine intrinzičnog kortizola snizile približno 86% (90% CI 82-89%).
English: The following guidance is based on the half-life of darunavir in the presence of cobicistat or ritonavir and the recommended dosing interval of approximately 12 hours (twice daily regimen) or approximately 24 hours (once daily regimen).
Croatian: Sljedeće smjernice temelje se na poluvijeku darunavira u prisutnosti kobicistata ili ritonavira te preporučenom intervalu doziranja od približno 12 sati (režim od dva puta na dan) ili približno 24 sata (režim od jedanput na dan).
English: Contains sodium methyl parahydroxybenzoate (E219).
Croatian: Sadrži natrijev metilparahidroksibenzoat (E219).
English: Open the bottle of PREZISTA oral suspension by pushing downward on the cap and twisting it counter-clockwise.
Croatian: Otvorite bočicu PREZISTA oralne suspenzije pritišćući čep prema dolje dok ga okrećete u smjeru suprotnom od kazaljke na satu.
English: The recommended dose of PREZISTA with low dose ritonavir should not exceed the recommended adult dose (600/100 mg twice daily or 800/100 mg once daily).
Croatian: Preporučena doza lijeka PREZISTA uz nisku dozu ritonavira ne smije prelaziti preporučenu dozu za odrasle (600/100 mg dva puta na dan ili 800/100 mg jedanput na dan).
English: After therapy with PREZISTA has been initiated, patients should be advised not to alter the dosage, dose form or discontinue therapy without discussing with their health care provider.
Croatian: Nakon početka terapije lijekom PREZISTA, bolesnicima se mora savjetovati da ne mijenjaju doziranje, oblik doze ili prekidaju terapiju, bez da o tome nisu razgovarali s liječnikom.
English: During the clinical development program (N=2,613 treatment-experienced subjects who initiated therapy with PREZISTA/ritonavir 600/100 mg twice daily), 51.3% of subjects experienced at least one adverse reaction.
Croatian: Tijekom razvojnog kliničkog programa (n=2613 prethodno liječenih ispitanika kod kojih je započela terapija lijekovima PREZISTA/ritonavir od 600/100 mg dva puta na dan) 51,3% ispitanika doživjelo je najmanje jednu nuspojavu.
English: The dose of cobicistat to be used with PREZISTA in children less than 18 years of age has not been established.
Croatian: Doza kobicistata koju treba uzeti uz lijek PREZISTA u djece dobi mlađe od 18 godina nije ustanovljena.
English: Paediatric population The safety assessment in paediatric patients is based on the 48-week analysis of safety data from three Phase II trials.
Croatian: Pedijatrijska populacija Procjena sigurnosti u pedijatrijskih bolesnika temelji se na 48-tjednoj analizi podataka o sigurnosti dobivenim u tri ispitivanja faze II.
English: PREZISTA 100 mg/ml oral suspension darunavir
Croatian: PREZISTA 100 mg/ml oralna suspenzija darunavir
English: Excipient with known effect: sodium methyl parahydroxybenzoate (E219) 3.43 mg/ml.
Croatian: Pomoćna tvar s poznatim učinkom: natrijev metilparahidroksibenzoat (E219) 3,43 mg/ml.
English: Therefore, PREZISTA tablets should be taken with ritonavir and with food.
Croatian: Stoga se PREZISTA tablete moraju uzimati s ritonavirom te uz hranu.
English: Co-administration with boosted PREZISTA may lead to a substantial increase in exposure to dabigatran or ticagrelor.
Croatian: Istodobna primjena s pojačanom PREZISTOM može dovesti do značajnog povećanja izloženosti dabigatranu ili tikagreloru.
English: CORTICOSTEROIDS Corticosteroids primarily metabolised by CYP3A (including betamethasone, budesonide, fluticasone, mometasone, prednisone, triamcinolone)
Croatian: KORTIKOSTEROIDI Kortikosteroidi prvenstveno metabolizirani putem CYP3A (uključujući betametazon, budezonid, flutikazon, mometazon, prednizon, triamcinolon)
English: - Corticosteroids including betamethasone, budesonide, fluticasone, mometasone, prednisone, triamcinolone.
Croatian: - kortikosteroidi uključujući betametazon, budezonid, flutikazon, mometazon, prednizon, triamcinolon.
English: Investigations common increased blood creatinine * these adverse drug reactions have not been reported in clinical trial experience with darunavir/cobicistat but have been noted with darunavir/ritonavir treatment and could be expected with darunavir/cobicistat too.
Croatian: Pretrage često povišen kreatinin u krvi * ove nuspojave nisu prijavljene tijekom iskustva iz kliničkih ispitivanja s darunavirom/kobicistatom ali su zabilježene tijekom liječenja s darunavirom/ritonavirom, te se također mogu očekivati s darunavirom/kobicistatom.
English: Insert the supplied oral dosing pipette all the way into the bottle.
Croatian: Umetnite priloženu pipetu za oralno doziranje do kraja u bočicu.
English: This protein binding is concentration-dependent indicative for saturation of binding.
Croatian: Ovo je vezanje na protein ovisno o koncentraciji i pokazatelj je mogućnosti zasićenja vezanja.
English: Dose adjustment for buprenorphine may not be necessary when co-administered with boosted PREZISTA but a careful clinical monitoring for signs of opiate toxicity is recommended.
Croatian: Prilagodba doze buprenorfina možda neće biti potrebna kada se primjenjuje istodobno s pojačanom PREZISTOM, ali se preporučuje pažljivo kliničko praćenje znakova opijatne toksičnosti.
English: Given that digoxin has a narrow therapeutic index, it is recommended that the lowest possible dose of digoxin should initially be prescribed in case digoxin is given to patients on darunavir/ritonavir therapy.
Croatian: Budući da digoksin ima uzak terapijski indeks, preporučuje se inicijalno prepisati najnižu moguću dozu digoksina u slučaju kada se digoksin daje bolesnicima koji su na terapiji darunavirom/ritonavirom.
English: Drug-induced hepatitis (e.g. acute hepatitis, cytolytic hepatitis) has been reported with PREZISTA.
Croatian: Lijekom izazvan hepatitis (npr. akutni hepatitis, citolitički hepatitis) bio je prijavljen kod liječenja lijekom PREZISTA.
English: When the recommendation is the same for PREZISTA when co-administered with a low dose ritonavir or cobicistat, the term “boosted PREZISTA” is used.
Croatian: Kada je preporuka ista za lijek PREZISTA istodobno primijenjen s niskom dozom ritonavira ili kobicistatom, korišten je termin „pojačana PREZISTA“.
English: Your child's doctor will determine the appropriate dosing regimen for your child. - The child must take PREZISTA with food.
Croatian: Liječnik Vašeg djeteta će odrediti prikladni režim doziranja za Vaše dijete.
English: PREZISTA in combination with ritonavir has no or negligible influence on the ability to drive and use machines.
Croatian: PREZISTA u kombinaciji s ritonavirom ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Some side effects are typical for anti-HIV medicines in the same family as PREZISTA.
Croatian: Neke su nuspojave tipične za lijekove protiv HIV-a koji spadaju u istu skupinu kao i PREZISTA.
English: As limited information is available on the use of PREZISTA in patients aged 65 and over, caution should be exercised in the administration of PREZISTA in elderly patients, reflecting the greater frequency of decreased hepatic function and of concomitant disease or other therapy (see sections 4.2 and 5.2).
Croatian: S obzirom da su dostupni ograničeni podaci o primjeni lijeka PREZISTA kod bolesnika u dobi od 65 godina i više, nužan je oprez kod primjene lijeka PREZISTA u starijih bolesnika zbog povećane učestalosti smanjene funkcije jetre, te istodobne bolesti ili druge terapije (vidjeti dijelove 4.2 i 5.2).
English: Given that digoxin has a narrow therapeutic index, it is recommended that the lowest possible dose of digoxin should initially be prescribed in case digoxin is given to patients on boosted PREZISTA therapy.
Croatian: Budući da digoksin ima uzak terapijski indeks, preporučuje se inicijalno prepisati najnižu moguću dozu digoksina u slučaju kada se digoksin daje bolesnicima koji su na terapiji pojačanom PREZISTOM.
English: PREZISTA should not be used in children - below 3 years of age, because of safety concerns (see sections 4.4 and 5.3), or, - less than 15 kg body weight, as the dose for this population has not been established in a sufficient number of patients (see section 5.1).
Croatian: PREZISTA se ne smije primjenjivati kod djece - uzrasta ispod 3 godine, zbog sigurnosnih razloga (vidjeti dijelove 4.4 i 5.3), ili, - s manje od 15 kg tjelesne težine, jer doza za ovu populaciju nije ustanovljena na dovoljnom broju bolesnika (vidjeti dio 5.1).
English: The child must take PREZISTA every day and always in combination with 100 milligram of ritonavir and with food.
Croatian: Dijete mora uzeti lijek PREZISTA svaki dan i uvijek u kombinaciji sa 100 miligrama ritonavira i uz hranu.
English: an up to five-fold increase was seen in a limited subset of subjects
Croatian: kod limitirane podskupine ispitanika primijećeno je povišenje do pet puta
English: Pack size of one bottle.
Croatian: Veličina pakiranja: jedna bočica.
English: Do not use this medicine after the expiry date which is stated on the carton and on the bottle after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i bočici iza oznake „Rok valjanosti“.
English: PREZISTA 100 mg/ml oral suspension
Croatian: PREZISTA 100 mg/ml oralna suspenzija
English: Pack size of one bottle or three bottles per carton.
Croatian: Veličina pakiranja s jednom ili tri bočice u kutiji.
English: However, when HIV genotypic testing is not feasible, the PREZISTA/ritonavir once daily dosing regimen is recommended in HIV protease inhibitor-naïve paediatric patients and the twice daily dosing regimen is recommended in HIV protease inhibitor-experienced patients.
Croatian: Međutim, kada testiranje genotipa HIV-a nije moguće provesti, preporučeni režim doziranja lijeka PREZISTA/ritonavir je jedanput na dan u pedijatrijskih bolesnika koji prethodno nisu uzimali inhibitore proteaze HIV-a i dva puta na dan, preporučeni režim doziranja u bolesnika koji su prethodno uzimali inhibitore proteaze HIV-a.
English: Clinical monitoring for central nervous system toxicity associated with increased exposure to efavirenz may be indicated when PREZISTA co-administered with low dose ritonavir is given in combination with efavirenz.
Croatian: Kliničko praćenje toksičnosti na središnji živčani sustav povezano s povećanom izloženosti efavirenzu može biti indicirano kada je PREZISTA istodobno primjenjena s niskom dozom ritonavira i dana u kombinaciji s efavirenzom.
English: Didanosine is to be administered on an empty stomach, thus it should be administered 1 hour before or 2 hours after PREZISTA/ritonavir given with food.
Croatian: Didanozin treba primijeniti na prazan želudac, odnosno treba ga primjeniti1 sat prije ili 2 sata nakon lijeka PREZISTA/ritonavir koji se uzimaju s hranom.
English: In addition, patients on a stable dose of these antidepressants who start treatment with boosted PREZISTA should be monitored for antidepressant response.
Croatian: Dodatno, bolesnike na stabilnoj dozi tih antidepresiva koji započnu liječenje s pojačanom PREZISTOM mora se pratiti na odgovor na antidepresive.
English: Data based on analyses at week 48
Croatian: Podaci temeljeni na analizama u 48. tjednu.
English: Pregnant or breast-feeding mothers should not take PREZISTA with cobicistat.
Croatian: Trudnice ili dojilje ne smiju uzimati lijek PREZISTA s kobicistatom.
English: PREZISTA might increase the risk for elevated potassium levels by drospirenone.
Croatian: PREZISTA može povećati rizik od nastanka povišenih razina kalija radi drospirenona.
English: The bottle neck is filled with a low density polyethylene (LDPE) insert that accommodates the dosing pipette.
Croatian: Vrat bočice je ispunjen umetkom od polietilena niske gustoće (LDPE) koji odgovara dozirnoj pipeti.
English: • antiretroviral therapy (ART)-naïve (see section 4.2).
Croatian: ● nisu prethodno liječeni antiretrovirusnom terapijom (ART) (vidjeti dio 4.2).
English: What PREZISTA contains - The active substance is darunavir.
Croatian: Što PREZISTA sadrži - Djelatna tvar je darunavir.
English: Patients should be instructed to take PREZISTA with low dose ritonavir within 30 minutes after completion of a meal.
Croatian: Bolesnike se mora uputiti da uzimaju lijek PREZISTA s niskom dozom ritonavira unutar 30 minuta nakon završetka obroka.
English: When administration of atorvastatin and boosted PREZISTA is desired, it is recommended to start with an atorvastatin dose of 10 mg once daily.
Croatian: Kada se želi primjeniti atorvastatin i pojačana PREZISTA, preporučuje se početi s dozom atorvastatina od 10 mg jedanput na dan.
English: Co-administration with PREZISTA/ritonavir may cause a large increase in the concentration of these medicines.
Croatian: Istodobna primjena s lijekom PREZISTA/ritonavir može izazvati velik porast koncentracije tih lijekova.
English: 100 milligram between 30 and 40 kilograms
Croatian: 100 miligrama između 30 and 40 kilograma
English: The metabolism of alfentanil is mediated via CYP3A, and may as such be inhibited by boosted PREZISTA.
Croatian: Metabolizam alfentanila posredovan je putem CYP3A, i kao takav može biti inhibiran pojačanom PREZISTOM.
English: Your doctor should do blood tests before you start PREZISTA.
Croatian: Prije započinjanja lijeka PREZISTA liječnik Vam treba napraviti krvne pretrage.
English: If you take more PREZISTA than you should Contact your doctor, pharmacist or nurse immediately.
Croatian: Ako uzmete više lijeka PREZISTA nego što ste trebali Odmah kontaktirajte svog liječnika, ljekarnika ili medicinsku sestru.
English: TLOVR non-VF censored algorithm based on HIV-1 RNA < 50 copies/ml, except for TITAN (HIV-1 RNA < 400 copies/ml) IAS-USA lists
Croatian: TLOVR ne-VF cenzoriran algoritam na temelju HIV-1 RNK < 50 kopija/ml, osim za ispitivanje TITAN (HIV-1 RNK < 400 kopija/ml)
English: The combination of boosted PREZISTA and artemether/lumefantrine can be used without dose adjustments; however, due to the increase in lumefantrine exposure, the combination should be used with caution.
Croatian: Kombinacija pojačane PREZISTE i artemeter/lumefantrina može se primijeniti bez prilagodbe doze, međutim, zbog povećane izloženosti lumefantrinu, tu kombinaciju se mora primjenjivati s oprezom.
English: During the clinical development program of raltegravir in treatment-experienced patients, rash, irrespective of causality, was more commonly observed with regimens containing PREZISTA/ritonavir + raltegravir compared to those containing PREZISTA/ritonavir without raltegravir or raltegravir without PREZISTA/ritonavir.
Croatian: Tijekom kliničkog razvojnog programa raltegravira, u prethodno liječenih bolesnika, opažen je osip, koji je, bez obzira na uzročno-posljedičnu povezanost, češće opažen s režimima primjene koji sadrže lijek PREZISTA/ritonavir + raltegravir u usporedbi na režime koji su sadržavali samo lijek PREZISTA/ritonavir bez raltegravira ili raltegravir bez lijeka PREZISTA/ritonavir.
English: - This medicine contains less than 1 mmol sodium (23 mg) per dosage unit, that is to say essentially ‘sodium-free'.
Croatian: . - Ovaj lijek sadrži manje od 1 mmol (23 mg) natrija po doznoj jedinici, tj. zanemarive količine natrija.
English: PREZISTA in combination with cobicistat or ritonavir has no or negligible influence on the ability to drive and use machines.
Croatian: PREZISTA u kombinaciji s kobicistatom ili ritonavirom ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Instructions for children - The child must take PREZISTA always together with ritonavir.
Croatian: Upute za djecu - Dijete uvijek mora uzimati lijek PREZISTA zajedno s ritonavirom.
English: PREZISTA 75 mg, 150 mg and 600 mg film-coated tablets 3 years
Croatian: PREZISTA 75 mg, 150 mg i 600 mg filmom obložene tablete 3 godine
English: The combination of PREZISTA and artemether/lumefantrine can be used without dose adjustments; however, due to the increase in lumefantrine exposure, the combination should be used with caution.
Croatian: Kombinacija lijeka PREZISTA i artemeter/lumefantrina može se primijeniti bez prilagodbe doze, međutim, zbog povećane izloženosti lumefantrinu, tu kombinaciju se mora primjenjivati s oprezom.
English: PREZISTA contains the active substance darunavir.
Croatian: PREZISTA sadrži djelatnu tvar darunavir.
English: Marketing Authorisation Holder Janssen-Cilag International NV, Turnhoutseweg 30, 2340 Beerse, Belgium
Croatian: Nositelj odobrenja za stavljanje lijeka u promet Janssen-Cilag International NV, Turnhoutseweg 30, 2340 Beerse, Belgija
English: The interaction trial showed a comparable daily systemic exposure for rifabutin between treatment at 300 mg once daily alone and 150 mg once every other day in combination with PREZISTA/ritonavir (600/100 mg twice daily) with an about 10-fold increase in the daily exposure to the active metabolite 25-O-desacetylrifabutin.
Croatian: Ispitivanje interakcije pokazalo je usporedivu dnevnu sistemsku izloženost za rifabutin između liječenja s 300 mg jedanput na dan samostalno i 150 mg jedanput svaki drugi dan u kombinaciji s lijekom PREZISTA/ritonavir (600/100 mg dva puta na dan) uz oko 10 puta veću dnevnu izloženost aktivnom metabolitu 25-O-desacetilrifabutinu.
English: The use of only 75 mg and 150 mg tablets or the 100 mg/ml oral suspension to achieve the recommended dose of PREZISTA could be appropriate when there is a possibility of hypersensitivity to specific colouring agents.
Croatian: Primjena samo tableta od 75 mg i 150 mg ili oralne suspenzije od 100 mg/ml da se dostigne preporučena doza lijeka PREZISTA može biti primjerena kada postoji mogućnost preosjetljivosti na specifična bojila.
English: Co-administration with strong CYP3A4 inhibitors is not recommended and caution is warranted, these interactions are described in the interaction table below (e.g. indinavir, azole antifungals such as clotrimazole).
Croatian: Istodobna primjena sa snažnim CYP3A4 inhibitorima se ne preporučuje i savjetuje se oprez, ove interakcije opisane su u tablici interakcija ispod (npr. indinavir, antifungalni azoli poput klotrimazola).
English: Pack includes a 6 ml dosing pipette with 0.2 ml gradations.
Croatian: U pakiranju je priložena dozirna pipeta od 6 ml s odmjernim oznakama svakih 0,2 ml.
English: It is not recommended to co-administer boosted PREZISTA with glecaprevir/pibrentasvir.
Croatian: Ne preporučuje se istodobna primjena pojačane PREZISTE s glekaprevirom/pibrentasvirom.
English: 100 milligram (1.2 milliliter)
Croatian: 100 miligrama (1,2 mililitra)
English: The use of 75 mg and 150 mg tablets to achieve the recommended dose is appropriate when there is a possibility of hypersensitivity to specific colouring agents, or difficulty in swallowing the 300 mg or 600 mg tablets.
Croatian: Primjena tableta od 75 mg i 150 mg za dostizanje preporučene doze primjerena je kada postoji mogućnost preosjetljivosti na specifična bojila ili teškoće pri gutanju tableta od 300 mg ili 600 mg.
English: - Swallow the tablets with a drink such as water or milk.
Croatian: - Progutajte tabletu s pićem poput vode ili mlijeka.
English: During the darunavir/ritonavir clinical development program (N=3,063), hepatitis was reported in 0.5% of patients receiving combination antiretroviral therapy with PREZISTA/ritonavir.
Croatian: Tijekom kliničkog razvojnog programa darunavira/ritonavira (n=3063), hepatitis je prijavljen kod 0,5% bolesnika koji su primali kombiniranu antiretrovirusnu terapiju lijekom PREZISTA/ritonavir.
English: Therefore, PREZISTA must not be used in patients with severe hepatic impairment (Child-Pugh Class C) (see sections 4.3, 4.4 and 5.2).
Croatian: Stoga se PREZISTA ne smije primjenjivati u bolesnika s teškim oštećenjem jetre (Child-Pugh stadij C) (vidjeti dijelove 4.3, 4.4 i 5.2).
English: These results were confirmed in the analysis of data at 96 weeks of treatment in the TITAN trial, with 60.4% of patients in the PREZISTA/ritonavir arm having HIV-1 RNA < 50 copies/ml at week 96 compared to 55.2% in the lopinavir/ritonavir arm [difference: 5.2%, 95% CI (-2.8; 13.1)].
Croatian: Ti su rezultati potvrđeni analizom podataka u 96. tjednu liječenja u ispitivanju TITAN, sa 60,4% bolesnika u skupini liječenoj lijekom PREZISTA/ritonavir koji su imali HIV-1 RNK < 50 kopija/ml u 96. tjednu u usporedbi s 55,2% u skupini liječenoj lopinavirom/ritonavirom [razlika: 5,2%, 95% CI (-2,8;13,1)].
English: Number of subjects with virologic failure a and phenotype data that show resistance to PIs at endpoint c, n/N
Croatian: Broj ispitanika s virološkim neuspjehom a i podaci o fenotipu koji pokazuju rezistenciju na IP na ishodu ispitivanja c, n/N
English: No new safety findings were identified in the 192 week analysis of the treatment-naïve subjects in which the mean treatment duration of PREZISTA/ritonavir 800/100 mg once daily was 162.5 weeks.
Croatian: U 192 tjednoj analizi nije bilo novih sigurnosnih nalaza u prethodno neliječenih ispitanika, a u kojih je srednja vrijednost trajanja liječenja lijekom PREZISTA/ritonavir od 800/100 mg jednaput na dan bila 162,5 tjedna.
English: Based on the different elimination pathways of the other NRTIs zidovudine, emtricitabine, stavudine, lamivudine, that are primarily renally excreted, and abacavir for which metabolism is not mediated by CYP450, no interactions are expected for these medicinal compounds and boosted PREZISTA.
Croatian: Na temelju različitih puteva eliminacije drugih NRTI-ova, zidovudina, emtricitabina, stavudina, lamivudina, koji se primarno izlučuju putem bubrega, te abakavira čiji metabolizam nije posredovan CYP450, ne očekuju se interakcije ovih lijekova i pojačane PREZISTE.
English: In addition, patients on a stable dose of these antidepressants who start treatment with PREZISTA with low dose ritonavir should be monitored for antidepressant response.
Croatian: Dodatno, bolesnike na stabilnoj dozi tih antidepresiva koji započnu liječenje s PREZISTOM s niskom dozom ritonavira mora se pratiti na odgovor na antidepresive.
English: Based on theoretical considerations PREZISTA is expected to increase alfuzosin plasma concentrations.
Croatian: Temeljeno na teorijskim postavkama očekuje se da će PREZISTA povećati koncentracije alfuzozina u plazmi.