FrancophonIA/ELRC3.0 huggingface dataset:
English: Relevant examples are cytomegalovirus retinitis, generalised and/or focal mycobacterial infections, and Pneumocystis jirovecii pneumonia.
Croatian: Relevantni primjeri su citomegalovirusni retinitis, generalizirane i/ili fokalne mikobakterijske infekcije i upala pluća prouzročena s Pneumocystis jirovecii
English: Caution should be used with medicinal products known to induce PR prolongations.
Croatian: Potreban je oprez kod primjene lijekova za koje se zna da produljuju PR-interval.
English: Cobicistat, does not directly treat your HIV, but boosts the levels of atazanavir in the blood.
Croatian: Kobicistat ne liječi HIV infekciju izravno, već povisuje razine atazanavira u krvi.
English: The recommended dose of EVOTAZ is one tablet once daily taken orally with food (see section 5.2).
Croatian: Preporučena doza lijeka EVOTAZ je jedna tableta jedanput na dan, a uzima se peroralno s hranom (vidjeti dio 5.2).
English: Quetiapine Lurasidone
Croatian: Kvetiapin Lurasidon
English: Tenofovir DF may decrease the AUC and Cmin of atazanavir.
Croatian: Tenofovir DF može sniziti AUC i Cmin atazanavira.
English: Integrase Inhibitors
Croatian: Inhibitori integraze
English: Co-administration of EVOTAZ and hormonal contraceptives should be avoided.
Croatian: Treba izbjegavati istodobnu primjenu lijeka EVOTAZ i hormonskih kontraceptiva.
English: It is important that you do not miss any doses of EVOTAZ or your other anti-HIV medicines.
Croatian: Važno je da ne propustite uzeti nijednu dozu lijeka EVOTAZ ni ostalih lijekova za liječenje HIV infekcije.
English: A long-term carcinogenicity study of cobicistat in rats revealed tumourigenic potential specific for this species that is regarded as of no relevance for humans.
Croatian: Dugoročno ispitivanje kancerogenosti kobicistata u štakora otkrilo je tumorogeni potencijal specifičan za tu vrstu, koji se ne smatra značajnim za ljude.
English: Alternative antibiotics should be considered.
Croatian: Treba razmotriti primjenu nekog drugog antibiotika.
English: This association was observed independently of exposure to tenofovir disoproxil.
Croatian: Ta povezanost je primjećena neovisno o izloženosti tenofovirdizoproksilu.
English: EVOTAZ is indicated in combination with other antiretroviral medicinal products for the treatment of HIV-1 infected adults without known mutations associated with resistance to atazanavir (see sections 4.4 and 5.1).
Croatian: EVOTAZ je indiciran u kombinaciji s drugim antiretrovirusnim lijekovima za liječenje odraslih osoba zaraženih virusom HIV-1 bez poznatih mutacija povezanih s rezistencijom na atazanavir (vidjeti dijelove 4.4 i 5.1).
English: Atazanavir was approximately 86% bound to human serum proteins over a concentration range of 100 to 10,000 ng/ml.
Croatian: Približno 86% atazanavira vezalo se za proteine u ljudskom serumu u rasponu koncentracija od 100 do 10 000 ng/ml.
English: Virologic response rate was evaluated in both treatment arms and virologic response was defined as achieving an undetectable viral load (<50 HIV-1 RNA copies/ml).
Croatian: Stopa virološkog odgovora ocjenjivala se u obje liječene skupine, a virološki se odgovor definirao kao postizanje nemjerljivog virusnog opterećenja (< 50 kopija HIV-1 RNK/ml).
English: EVOTAZ must not be used in combination with medicinal products that are substrates of CYP3A4 and have a narrow therapeutic index.
Croatian: EVOTAZ se ne smije primjenjivati u kombinaciji s lijekovima koji su supstrati za CYP3A4 i imaju uzak terapijski indeks.
English: The median terminal plasma half-life of cobicistat following administration of cobicistat is approximately 3-4 hours.
Croatian: Medijan terminalnog poluvijeka kobicistata u plazmi nakon primjene kobicistata iznosi približno 3-4 sata.
English: In study GS-US-216-0114, decreases in estimated creatinine clearance occurred early in treatment with cobicistat, after which they stabilised.
Croatian: U ispitivanju GS-US-216-0114, smanjenja procijenjenog klirensa kreatinina nastupila su u početnim fazama liječenja kobicistatom, nakon čega su se stabilizirala.
English: No differences in frequency of bilirubin elevations were observed between these patients and those without viral hepatitis.
Croatian: Nisu primijećene razlike u učestalosti povišenja razine bilirubina između tih bolesnika i onih bez virusnog hepatitisa.
English: e Includes subjects who discontinued for reasons other than an adverse event, death or lack or loss of efficacy,
Croatian: e Uključuje ispitanike koji su prekinuli liječenje zbog razloga koji nisu bili nuspojava, smrt ili nedostatak ili gubitak djelotvornosti, npr. povlačenje pristanka, gubitak iz praćenja.
English: Neither metabolite demonstrated in vitro antiviral activity.
Croatian: Nijedan metabolit nije pokazao antivirusnu aktivnost in vitro.
English: Rifampicin is a strong CYP3A4 inducer and has been shown to cause a 72% decrease in atazanavir AUC which can result in virological failure and resistance development.
Croatian: Rifampicin je snažan induktor CYP3A4 i pokazalo se da smanjuje AUC atazanavira za 72%, što može dovesti do virološkog neuspjeha i razvoja rezistencije.
English: A large prospective observational study has shown an association between an increased incidence of chronic kidney disease and cumulative exposure to atazanavir/ritonavir-containing regimen in HIV-infected patients with an initially normal eGFR.
Croatian: Veliko prospektivno opservacijsko ispitivanje pokazalo je povezanost između povećane incidencije kronične bubrežne bolesti i kumulativnog izlaganja režimu koji sadrži atazanavir/ritonavir u bolesnika zaraženih HIV-om s početno normalnom eGFR.
English: The compound selectively inhibits the virus-specific processing of viral Gag-Pol proteins in HIV-1 infected cells, thus preventing formation of mature virions and infection of other cells.
Croatian: Taj spoj selektivno inhibira za virus specifičnu obradu virusnih proteina Gag-Pol u stanicama zaraženima virusom HIV-1 te tako sprječava nastanak zrelih viriona i infekciju drugih stanica.
English: Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported; however, the reported time to onset is more variable and these events can occur many months after initiation of treatment (see section 4.4).
Croatian: Prijavljene su i autoimune bolesti (kao što je Gravesova bolest i autoimuni hepatitis); međutim, prijavljeno vrijeme do nastupa vrlo je varijabilno jer se ti događaji mogu javiti i više mjeseci nakon početka liječenja (vidjeti dio 4.4).
English: For patients who are taking tenofovir DF, it is not recommended to co-administer EVOTAZ with an H2-receptor antagonist.
Croatian: U bolesnika koji uzimaju tenofovir DF, ne preporučuje se primjena lijeka EVOTAZ istodobno s antagonistom H2-receptora.
English: If trazodone is co-administered with EVOTAZ, the combination should be used with caution and a lower dose of trazodone should be considered.
Croatian: Ako se trazodon primjenjuje istodobno s lijekom EVOTAZ, tu kombinaciju treba primjenjivati uz oprez te treba razmotriti nižu dozu trazadona.
English: It is unknown if cobicistat, the other component of EVOTAZ, is excreted in human milk but it has been shown in animals that it is excreted in milk.
Croatian: Nije poznato da li se drugi sastojak lijeka EVOTAZ, kobicistat izlučuje u majčino mlijeko, ali je u životinja dokazano da se izlučuje u mlijeko.
English: This effect on serum creatinine, leading to a decrease in the estimated creatine clearance, should be taken into consideration when EVOTAZ is administered to patients in whom the estimated creatinine clearance is used to guide aspects of their clinical management, including adjusting doses of co-administered medicinal products.
Croatian: Taj učinak na serumski kreatinin, koji smanjuje procijenjeni klirens kreatinina, treba uzeti u obzir kada se EVOTAZ primjenjuje u bolesnika u kojih procijenjeni klirens kreatinina služi kao smjernica za njihovo kliničko liječenje, uključujući prilagodbu doza istodobno primijenjenih lijekova.
English: If switching from atazanavir boosted with ritonavir to EVOTAZ, caution is required during the first two weeks of treatment with EVOTAZ, particularly if doses of any concomitantly administered medicinal products have been titrated or adjusted during use of ritonavir as a pharmacoenhancer (see section 4.5).
Croatian: U slučaju prelaska s atazanavira pojačanog ritonavirom na EVOTAZ, potreban je oprez tijekom prva dva tjedna liječenja lijekom EVOTAZ, osobito ako se doza bilo kojeg od istodobno primijenjenih lijekova titrirala ili prilagođavala tijekom primjene ritonavira kao farmakokinetičkog pojačivača (vidjeti dio 4.5).
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Croatian: U nekih bolesnika s uznapredovalom HIV-infekcijom (SIDA) i oportunističkom infekcijom u povijesti bolesti, mogu se pojaviti znakovi i simptomi upale uzrokovane prethodnim infekcijama ubrzo nakon početka liječenja HIV infekcije.
English: Ciclosporin Tacrolimus Sirolimus
Croatian: Ciklosporin Takrolimus Sirolimus
English: Interaction not studied with any of the components of EVOTAZ.
Croatian: Nije ispitana interakcija niti s jednom kompontentom EVOTAZA.
English: Data from concomitant use of parenteral midazolam with other protease inhibitors suggest a possible 3-4 fold increase in midazolam plasma levels.
Croatian: Podaci o istodobnoj primjeni parenteralnog midazolama s drugim inhibitorima proteaze ukazuju na moguće povišenje plazmatskih razina midazolama za 3-4 puta.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/15/1025/001-002
Croatian: EU/1/15/1025/001-002
English: Discontinued study drug due to other reasons and last available HIV-1 RNA <50 copies/mle
Croatian: Prekid primjene ispitivanog lijeka zbog drugih razloga i posljednja dostupna vrijednost HIV-1 RNK <50 kopija/mle
English: Co-administration of EVOTAZ and rivaroxaban may result in increased exposure to rivaroxaban and may lead to increased bleeding.
Croatian: Istodobna primjena lijeka EVOTAZ i rivaroksabana može povećati izloženost rivaroksabanu i dovesti do pojačanog krvarenja.
English: In clinical studies, paediatric patients 3 months to less than 18 years of age had a mean duration of treatment with atazanavir of 115 weeks.
Croatian: U kliničkim su ispitivanjima pedijatrijski bolesnici u dobi od 3 mjeseca do manje od 18 godina prosječno bili liječeni atazanavirom tijekom 115 tjedana.
English: If EVOTAZ is co-administered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Croatian: Ako se EVOTAZ primjenjuje istodobno s parenteralnim midazolamom, to treba učiniti u jedinici intenzivnog liječenja (JIL) ili sličnom okruženju koje omogućuje poman klinički nadzor i odgovarajuće zbrinjavanje u slučaju respiratorne depresije i/ili produljene sedacije.
English: If alternatives cannot be used, its use should only take place after medical evaluation and under close monitoring by your doctor for corticosteroid side effects.
Croatian: Ako se ne mogu primjenjivati zamjenski lijekovi, smije se započeti s primjenom tih lijekova tek nakon medicinske procjene i pod pomnim praćenjem liječnika radi eventualnih nuspojava kortikosteroida.
English: Cmax and AUCs after a high fat meal decreased 36% and 25% in comparison to a light meal, respectively; however, the 24-hour atazanavir concentration was similar when EVOTAZ was given with a light meal and a high fat meal.
Croatian: Nakon obroka s visokim udjelom masnoća Cmax se smanjio za 36%, a AUC za 25% u odnosu na lagan obrok; ipak, 24-satna koncentracija atazanavira bila je slična kada se EVOTAZ primjenjivao uz lagan obrok i obrok s s visokim udjelom masnoća.
English: If EVOTAZ is co-administered with irinotecan, patients should be closely monitored for adverse reactions related to irinotecan.
Croatian: Ako se EVOTAZ primjenjuje istodobno s irinotekanom, bolesnike je potrebno pažljivo pratiti zbog mogućih nuspojava povezanih s irinotekanom.
English: Immune reactivation syndrome and autoimmune disorders
Croatian: Sindrom imunološke reaktivacije i autoimuni poremećaji
English: For these sedatives/hypnotics, dose reduction may be necessary and concentration monitoring is recommended.
Croatian: Možda će trebati smanjiti dozu tih sedativa/hipnotika, a preporučuje se i nadzirati njihove koncentracije.
English: Stevens-Johnson syndromea,b, vesiculobullous rash, eczema, vasodilatation
Croatian: Stevens-Johnsonov sindroma,b, vezikulobulozni osip, ekcem, vazodilatacija
English: When co-administered with tenofovir DF, it is recommended that EVOTAZ and tenofovir DF 300 mg be given together with food.
Croatian: Pri istodobnoj primjeni s tenofovirom DF, preporučuje se zajedno primijeniti EVOTAZ i 300 mg tenofovira DF, s hranom.
English: There were no tumorigenic findings in male mice or in rats.
Croatian: Nisu pronađeni znakovi tumorogenog djelovanja u mužjaka miša ni u štakora.
English: In clinical studies, atazanavir has been shown to induce dyslipidaemia to a lesser extent than comparators.
Croatian: U kliničkim se ispitivanjima pokazalo da atazanavir izaziva dislipidemiju u manjem opsegu nego usporedni lijekovi.
English: Atazanavir binds to both alpha-1-acid glycoprotein (AAG) and albumin to a similar extent (89% and 86%, respectively, at 1,000 ng/ml).
Croatian: Atazanavir se u sličnoj mjeri veže i za alfa-1-kiseli glikoprotein i za albumin (89% odnosno 86%, pri 1000 ng/ml).
English: Alternative forms of contraception (non-hormonal) should be considered (see section 4.5).
Croatian: Treba razmotriti druge (nehormonske) oblike kontracepcije (vidjeti dio 4.5).
English: Data are not available to make recommendations regarding the use of EVOTAZ with other oral contraceptives.
Croatian: Nema dostupnih podataka na temelju kojih se može dati preporuka vezano uz primjenu lijeka EVOTAZ s drugim oralnim kontraceptivima.
English: Protease inhibitors: EVOTAZ in combination with other protease inhibitors is not recommended because co-administration may not provide adequate protease inhibitor exposure.
Croatian: Inhibitori proteaze: Ne preporučuje se primjena lijeka EVOTAZ u kombinaciji s drugim inhibitorima proteaze jer njihova istodobna primjena možda neće pružiti odgovarajuću izloženost inhibitorima proteaze.
English: Cobicistat inhibits the transporters p-glycoprotein (P-gp), BCRP, MATE1, OATP1B1 and OATP1B3.
Croatian: Kobicistat inhibira prijenosnike p-glikoprotein (P-gp), BCRP, MATE1, OATP1B1 i OATP1B3.
English: The choice of EVOTAZ in adult patients should be based on individual viral resistance testing and the patient's treatment history (see section 5.1).
Croatian: Izbor lijeka EVOTAZ u odraslih bolesnika mora se temeljiti na individualnom ispitivanju rezistencije na virus i prethodnim terapijama koje je bolesnik primao (vidjeti dio 5.1).
English: Do not take sildenafil with EVOTAZ when sildenafil is used for the treatment of pulmonary arterial hypertension.
Croatian: Nemojte uzimati sildenafil s lijekom EVOTAZ kada se sildenafil primjenjuje za liječenje plućne arterijske hipertenzije.
English: Although not studied, there is a potential for an increase in pravastatin or fluvastatin exposure when co-administered with protease inhibitors.
Croatian: Iako interakcija nije ispitivana, postoji mogućnost povećane izloženosti pravastatinu ili fluvastatinu kada se oni primjenjuju istodobno s inhibitorima proteaze.
English: Atazanavir was negative in an Ames reverse-mutation assay but did induce chromosomal aberrations in vitro in both the absence and presence of metabolic activation.
Croatian: Atazanavir je pokazao negativan rezultat na Amesovom testu reverznih mutacija, ali je izazvao kromosomske aberacije in vitro i u prisutnosti i u odsutnosti metaboličke aktivacije.
English: Ex vivo rabbit studies and in vivo dog studies suggest that cobicistat has a low potential for QT prolongation, and may slightly prolong the PR interval and decrease left ventricular function at mean concentrations at least 10-fold higher than the human exposure at the recommended 150 mg daily dose.
Croatian: Ex vivo ispitivanja u kunića i in vivo ispitivanja u pasa ukazuju na to da kobicistat ima nizak potencijal za produljenje QT-intervala te da može malo produljiti PR-interval i smanjiti funkciju lijeve klijetke pri srednjim koncentracijama najmanje 10 puta većima od izloženosti u ljudi koja se postiže nakon primjene preporučene dnevne doze od 150 mg.
English: Atazanavir increased opacity of bovine corneas in an in vitro ocular irritation study, indicating it may be an ocular irritant upon direct contact with the eye.
Croatian: Atazanavir je povećao neprozirnost goveđih rožnica u jednom in vitro ispitivanju nadraženosti oka, što ukazuje na to da bi on mogao biti iritans za oči u slučaju izravnog kontakta s okom.
English: Some examples include, but are not limited to etravirine, nevirapine, efavirenz, boceprevir, fluticasone and bosentan (see Table 1).
Croatian: Neki primjeri uključuju, između ostalog etravirin, nevirapin, efavirenz, boceprevir, flutikazon i bosentan (vidjeti Tablicu 1).
English: Human experience of acute overdose with EVOTAZ is limited.
Croatian: Iskustvo s akutnim predoziranjem lijekom EVOTAZ u ljudi je ograničeno.
English: Clinical monitoring is recommended when co-administered with EVOTAZ and a dose reduction of the beta-blocker may be necessary.
Croatian: Kod istodobne primjene s lijekom EVOTAZ preporučuje se kliničko praćenje, a možda će biti potrebno i smanjenje doze beta-blokatora.
English: Two minor metabolites of atazanavir in plasma have been characterised.
Croatian: Opisana su dva sporedna metabolita atazanavira u plazmi.
English: Didanosine should be taken in the fasted state 2 hours after EVOTAZ taken with food.
Croatian: Didanozin treba uzeti natašte 2 sata nakon uzimanja lijeka EVOTAZ s hranom.
English: In clinical trials of antiretroviral treatment naive patients treated with unboosted atazanavir, the I50L substitution, sometimes in combination with an A71V change, is the signature resistance substitution for atazanavir.
Croatian: U kliničkim ispitivanjima antiretrovirusnog liječenja nepojačanim atazanavirom u bolesnika koji prethodno nisu bili liječeni, supstitucija I50L, ponekad u kombinaciji s promjenom na A71V, bila je tipična za rezistenciju na atazanavir.
English: A safe and effective dose in combination with EVOTAZ has not been established for sildenafil when used to treat pulmonary arterial hypertension.
Croatian: Nije ustanovljena sigurna i učinkovita doza sidenafila u kombinaciji s lijekom EVOTAZ kad se sildenafil primjenjuje za liječenje plućne arterijske hipertenzije.
English: In patients with pre-existing conduction problems (second degree or higher atrioventricular or complex bundle-branch block), EVOTAZ should be used with caution and only if the benefits exceed the risk (see section 5.1).
Croatian: U bolesnika s već prisutnim poremećajima provođenja (atrioventrikularni blok drugog ili višeg stupnja ili kompletni blok grane), EVOTAZ treba primjenjivati uz oprez i samo ako su koristi od liječenja veće od rizika (vidjeti dio 5.1).
English: Antineoplastics
Croatian: Antineoplastici
English: For the treatment of erectile dysfunction, it is recommended that when co-administered with EVOTAZ, sildenafil should be used with caution at reduced doses of 25 mg every 48 hours; tadalafil should be used with caution at reduced doses of 10 mg every 72 hours; vardenafil should be used with caution at reduced doses of no more than 2.5 mg every 72 hours.
Croatian: Kada se liječenje erektilne disfunkcije provodi istodobno s lijekom EVOTAZ, sildenafil treba primjenjivati uz oprez u sniženoj dozi od 25 mg svakih 48 sati; tadalafil treba primjenjivati uz oprez u sniženoj dozi od 10 mg svaka 72 sata; vardenafil treba primjenjivati uz oprez u sniženoj dozi od najviše 2,5 mg svaka 72 sata.
English: In particular, atazanavir boosted with cobicistat is more sensitive for CYP3A induction (see section 4.3 and the interaction table).
Croatian: Osobito je važno napomenuti da je atazanavir pojačan kobicistatom osjetljiviji na indukciju CYP3A (vidjeti dio 4.3 i tablicu interakcija).
English: Based on these data and because cobicistat is not expected to have a significant impact on the pharmacokinetics of NRTIs, the co-administration of EVOTAZ with these medicinal products is not expected to significantly alter the exposure of the co-administered medicinal products.
Croatian: Na temelju ovih podataka i s obzirom da se ne očekuje značajan utjecaj kobicistata na farmakokinetiku NRTI-jeva, ne očekuje se da će istodobna primjena lijeka EVOTAZ i navedenih lijekova značajno promijeniti izloženost tim istodobno primijenjenim lijekovima.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to combination antiretroviral therapy (CART).
Croatian: Iako se smatra da postoji više uzroka osteonekroze (uključujući primjenu kortikosteroida, konzumaciju alkohola, tešku imunosupresiju, povišen indeks tjelesne mase), slučajevi osteonekroze prijavljeni su osobito u bolesnika s uznapredovalom HIV bolešću i/ili dugotrajnom izloženošću kombiniranoj antiretrovirusnoj terapiji.
English: Atazanavir has been shown in vivo not to induce its own metabolism, nor to increase the biotransformation of some medicinal products metabolised by CYP3A4.
Croatian: Pokazalo se da atazanavir in vivo ne inducira vlastiti metabolizam i ne pospješuje biotransformaciju nekih lijekova koji se metaboliziraju putem CYP3A4.
English: Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)
Croatian: Nukleozidni/nukleotidni inhibitori reverzne transkriptaze (NRTI)
English: In a multiple-dose study in HIV-infected patients dosed with 400 mg of atazanavir once daily with a light meal for 12 weeks, atazanavir was detected in the cerebrospinal fluid and semen.
Croatian: U ispitivanju višestrukih doza u bolesnika s HIV infekcijom koji su primali atazanavir u dozi od 400 mg jedanput na dan uz lagan obrok tijekom 12 tjedana, atazanavir je pronađen u cerebrospinalnom likvoru i sjemenu.
English: Dolutegravir is not expected to affect the pharmacokinetics of EVOTAZ.
Croatian: Ne očekuje se da će dolutegravir utjecati na farmakokinetiku lijeka EVOTAZ.
English: For patients not taking tenofovir, EVOTAZ once daily with food should be administered simultaneously with, and/or at least 10 hours after, a dose of the H2-receptor antagonist.
Croatian: U bolesnika koji ne uzimaju tenofovir, EVOTAZ primijenjen jedanput na dan s hranom treba uzimati u isto vrijeme s dozom antagonista receptora H2 i/ili najmanje 10 sati nakon njegove primjene.
English: Atazanavir, simultaneous administration with ddI+d4T (fasted)
Croatian: Atazanavir, primjena u isto vrijeme s ddI+d4T (natašte)
English: During in vitro studies, cloned human cardiac potassium channel (hERG), was inhibited by 15% at a concentration (30 μM) of atazanavir corresponding to 30 fold the free drug concentration at Cmax in humans.
Croatian: Tijekom ispitivanja in vitro, inhibicija kloniranog kalijevog kanala iz ljudskog srca (hERG) iznosila je 15% pri koncentraciji (30 μM) atazanavira koja je bila 30 puta veća od koncentracije slobodnog lijeka pri vrijednosti Cmax u ljudi.
English: Psychiatric disorders common insomnia, abnormal dreams uncommon depression, sleep disorder, disorientation, anxiety
Croatian: Psihijatrijski poremećaji često nesanica, neuobičajeni snovi manje često depresija, poremećaj spavanja, dezorijentacija, anksioznost
English: Patients co-infected with hepatitis B and/or hepatitis C virus
Croatian: Bolesnici s istodobnom infekcijom virusom hepatitisa B i/ili hepatitisa C
English: Sildenafil is also used for the treatment of erectile dysfunction.
Croatian: Sildenafil se primjenjuje i za liječenje erektilne disfunkcije.
English: 25-O-desacetyl-rifabutin: AUC: ↑525% Cmax: ↑384% Cmin: ↑394%
Croatian: 25-O-dezacetil-rifabutin: AUC: ↑525% Cmax: ↑384% Cmin: ↑394%