FrancophonIA/ELRC3.0 huggingface dataset:
English: TIENAM may be used in the management of neutropenic patients with fever that is suspected to be due to a bacterial infection.
Danish: TIENAM kan anvendes til behandling af neutropene patienter med feber, der mistænkes for at være forårsaget af en bakteriel infektion.
English: • Staining of the teeth and/or tongue
Danish: • Misfarvning af tænder og/eller tunge
English: Paediatric population with renal impairment
Danish: Pædiatrisk population med nyreinsufficiens
English: TIENAM is indicated for the treatment of the following infections in adults and children 1 year of age and above (see sections 4.4 and 5.1):
Danish: TIENAM er indiceret til behandling af følgende infektioner hos voksne og børn ≥ 1 år (se pkt.
English: • Skin peeling (toxic epidermal necrolysis)
Danish: • Hudafskalning (toksisk epidermal nekrolyse)
English: • Abnormal liver function detected by blood tests
Danish: • Unormal leverfunktion påvist via blodprøver
English: Cilastatin is a specific inhibitor of dehydropeptidase-I enzyme and effectively inhibits metabolism of imipenem so that concomitant administration of imipenem and cilastatin allows therapeutic antibacterial levels of imipenem to be attained in both urine and plasma.
Danish: Cilastatin er en specifik hæmmer af dehydropeptidase-I-enzymet og hæmmer effektivt metaboliseringen af imipenem, således at samtidig administration af imipenem og cilastatin resulterer i, at en terapeutisk antibakteriel koncentration af imipenem kan opnås i både urin og plasma.
English: • complicated intra-abdominal infections
Danish: • komplicerede intra-abdominale infektioner
English: Before initiating therapy with TIENAM, careful inquiry should be made concerning previous hypersensitivity reactions to carbapenems, penicillins, cephalosporins, other beta-lactams and other allergens (see section 4.3).
Danish: Før behandling med TIENAM initieres, skal patienterne udspørges grundigt med hensyn til forudgående overfølsomhedsreaktioner over for carbapenemer, penicilliner, cefalosporiner, andre beta-lactam-lægemidler og andre allergener (se pkt.
English: Hence close adherence to recommended dose schedules is urged especially in these patients (see section 4.2).
Danish: Derfor er nøje overholdelse af det anbefalede doseringsskema vigtig, specielt hos disse patienter (se pkt.
English: Each dose of 500 mg/500 mg should be given by intravenous infusion over 20 to 30 minutes.
Danish: En dosis på ≤500 mg/500 mg skal gives ved intravenøs infusion over 20 - 30 minutter.
English: • Infection affecting the lungs (pneumonia)
Danish: • Infektioner der angriber lungerne (lungebetændelse)
English: However, there are some side effects (such as hallucination, dizziness, somnolence, and vertigo) associated with this product that may affect some patients' ability to drive or operate machinery (see section 4.8).
Danish: Der er dog bivirkninger (som hallucinationer, svimmelhed, døsighed og vertigo) forbundet med dette præparat, som kan påvirke nogle patienters evne til at føre motorkøretøj eller betjene maskiner (se pkt.
English: It is recommended that infections suspected or proven to be due to less susceptible bacterial species (such as Pseudomonas aeruginosa) and very severe infections (e.g. in neutropenic patients with a fever) should be treated with 25/25 mg/kg administered every 6 hours.
Danish: Det anbefales, at infektioner, der mistænkes at skyldes, eller som bevisligt skyldes mindre følsomme bakterier (såsom Pseudomonas aeruginosa) samt meget svære infektioner (f.eks. hos neutropene patienter med feber) behandles med 25/25 mg/kg hver 6. time.
English: The medicinal product is supplied in packs of 1 vial, 10 vials and 25 vials.
Danish: Lægemidlet findes i pakninger med 1 hætteglas, 10 hætteglas og 25 hætteglas.
English: Concomitant administration of TIENAM and probenecid doubled the plasma level and half-life of cilastatin, but had no effect on urine recovery of cilastatin.
Danish: Samtidig administration af TIENAM og probenecid fordoblede plasmakoncentrationen og halveringstiden af cilastatin men havde ingen indflydelse på genfindingen af cilastatin i urinen.
English: • Changes in the amount of urine, changes in urine colour
Danish: • Ændret mængde urin, urinmisfarvning
English: No further cilastatin appeared in the urine thereafter.
Danish: Derefter sås ingen yderligere urinudskillelse af cilastatin.
English: What TIENAM contains - The active substances are imipenem and cilastatin.
Danish: YDERLIGERE OPLYSNINGER TIENAM indeholder: Aktive stoffer: Imipenem og cilastatin.
English: • Chest discomfort, difficulty breathing, abnormally fast and superficial breathing, pain in the upper spine
Danish: • Brystgener, vejrtrækningsproblemer, unormalt hurtig eller overfladisk vejrtrækning, smerte i øvre del af rygraden
English: If you are concerned that you may have missed a dose, contact your doctor or another healthcare professional immediately.
Danish: Hvis De er bekymret for, om De mangler at få en dosis, skal De kontakte en læge eller anden sundhedspersonale med det samme.
English: Reconstitution:
Danish: Rekonstituering:
English: The patient should receive TIENAM after haemodialysis and at 12 hour intervals timed from the end of that haemodialysis session.
Danish: Patienterne bør have TIENAM efter hæmodialysen og med 12 timers interval, regnet fra afslutning af hæmodialysen.
English: Symptoms of overdose that can occur are consistent with the adverse reaction profile; these may include seizures, confusion, tremors, nausea, vomiting, hypotension, bradycardia.
Danish: De symptomer på overdosering, som kan forekomme, svarer til bivirkningsprofilen; disse kan være krampeanfald, konfusion, tremor, kvalme, opkastning, hypotension, bradykardi.
English: Multiple dosing has no effect on the pharmacokinetics of either imipenem or cilastatin, and no accumulation of imipenem/cilastatin was observed (see section 4.2).
Danish: Multipel dosering havde ingen indflydelse på farmakokinetikken af hverken imipenem eller cilastatin, og der sås ingen akkumulation af imipenem/cilastatin (se pkt.
English: The pharmacokinetics of imipenem in patients with hepatic insufficiency have not been established.
Danish: Imipenems farmakokinetik hos patienter med nedsat leverfunktion er ikke fastlagt.
English: The usual dose for children one year of age or older is 15/15 or 25/25 mg/kg/dose every 6 hours.
Danish: Den sædvanlige dosis til børn i alderen 1 år eller ældre er 15/15 eller 25/25 mg/kg/dosis hver 6. time.
English: TIENAM is to be reconstituted and further diluted (see section 6.2, 6.3 and 6.6) prior to administration.
Danish: 6.2, 6.3 og 6.6) før administration.
English: Decreases in valproic acid levels that may fall below the therapeutic range have been reported when valproic acid was co-administered with carbapenem agents.
Danish: Der er set nedsat valproinsyrekoncentration, som kan falde til under det terapeutiske område, når valproinsyre blev givet sammen med carbapenem.
English: There are some side effects associated with this product (such as seeing, hearing, or feeling something that is not there, dizziness, sleepiness, and a spinning sensation) that may affect some patients' ability to drive or operate machinery (see section 4).
Danish: Der er nogle bivirkninger forbundet med dette præparat (såsom hallucinationer (se, høre eller føle ting som i virkeligheden ikke er der), svimmelhed, søvnløshed og en snurrende bevægelsesfornemmelse), som kan påvirke nogle patienters evne til at køre bil eller motorcykel eller betjene maskiner (se pkt.
English: When doses of imipenem-cilastatin sodium (approximately 100/100 mg/kg/day or approximately 3 times the usual recommended daily human intravenous dose) were administered to pregnant cynomolgus monkeys at an intravenous infusion rate which mimics human clinical use, there was minimal maternal intolerance (occasional emesis), no maternal deaths, no evidence of teratogenicity, but an increase in embryonic loss relative to control groups (see section 4.6).
Danish: Når der blev givet doser af imipenem-cilastatinnatrium (ca. 100/100 mg/kg/dag eller ca. 3 gange så meget som den sædvanligt anbefalede humane intravenøse dosis) til gravide cynomolgus-aber med en infusionshastighed, som svarer til klinisk brug hos mennesker, påvistes minimal maternal intolerance (lejlighedsvis opkastning), ingen dødsfald under graviditet, ingen tegn på teratogenicitet, men flere tilfælde af tidlig spontan abort i forhold til kontrolgrupperne (se pkt.
English: Oral anti-coagulants
Danish: Orale antikoagulantia
English: LIST OF EXCIPIENTS Sodium bicarbonate (E500)
Danish: LISTE OVER HJÆLPESTOFFER Natriumhydrogencarbonat (E500)
English: • Inflammation of stomach or intestine (gastro-enteritis)
Danish: • Betændelsestilstand i mave eller tarm (gastro-enteritis)
English: • Streptococcus A, B, C, G: The beta-lactam susceptibility of beta-haemolytic streptococcus groups A,
Danish: • Streptococcus A, B, C, G: Beta-lactam-følsomheden over for beta-hæmolytiske streptokokker gruppe A, B, C og G er udledt fra penicillinfølsomheden.
English: The plasma half-life of imipenem was one hour.
Danish: Imipenems plasmahalveringstid var l time.
English: TIENAM should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
Danish: TIENAM bør kun anvendes under graviditet, hvis den potentielle fordel kan retfærdiggøre den potentielle risiko for fostret.
English: 25 vials
Danish: 25 hætteglas
English: Patients with creatinine clearances of 5 ml/min/1.73 m2 should not receive TIENAM unless haemodialysis is instituted within 48 hours.
Danish: Patienter med kreatinin-clearance 5 ml/min./1,73 m2 bør ikke få TIENAM, medmindre hæmodialyse institueres inden for 48 timer.
English: It is recommended that infections suspected or proven to be due to less susceptible bacterial species (such as Pseudomonas aeruginosa) and very severe infections (e.g. in neutropenic patients with a fever) should be treated with 1000 mg/1000 mg administered every 6 hours.
Danish: Det anbefales, at infektioner der mistænkes at skyldes, eller som bevisligt skyldes mindre følsomme bakteriestammer (såsom Pseudomonas aeruginosa) samt meget svære infektioner (f.eks. hos neutropene patienter med feber) behandles med 1.000 mg/1.000 mg hver 6. time.
English: Increases in serum transaminases and in alkaline phosphatase are also commonly reported.
Danish: Stigning i serumaminotransferaser og basisk fosfatase er også hyppigt set.
English: A positive direct Coombs' test, prolonged prothrombin time, decreased haemoglobin, increases in serum bilirubin, elevations in serum creatinine, elevations in blood urea nitrogen
Danish: Ikke almindelig Positiv direkte Coombs test, forlænget protrombintid, fald i hæmaglobin, stigning i serumbilirubin, forhøjet serumkreatinin, forhøjet blod-ureanitrogen
English: Symptoms of overdose may include seizures, confusion, tremors, nausea, vomiting, low blood pressure and slow heart rate.
Danish: Symptomer på overdosering kan omfatte krampeanfald, forvirring, rysten, kvalme, opkastning, lavt blodtryk og langsom hjerterytme (puls).
English: Urine concentrations of imipenem exceeded 10 g/ml for up to eight hours after a 500 mg/500 mg dose of TIENAM.
Danish: Koncentrationen af imipenem i urinen oversteg 10 g/ml i op til 8 timer efter indgift af en TIENAM-dosis på 500 mg/500 mg.
English: Anticonvulsant therapy should be continued in patients with a known seizure disorder.
Danish: Antikonvulsiv behandling skal fortsætte hos patienter med krampelidelse.
English: Animal studies showed that the toxicity produced by imipenem, as a single entity, was limited to the kidney.
Danish: Dyreforsøg har vist, at toksiciteten af imipenem indgivet alene var begrænset til nyrerne.
English: In clinical trials including 1,723 patients treated with imipenem/cilastatin intravenous the most frequently reported systemic adverse reactions that were reported at least possibly related to therapy were nausea (2.0%), diarrhoea (1.8%), vomiting (1.5%), rash (0.9%), fever (0.5%), hypotension (0.4%), seizures (0.4%) (see section 4.4), dizziness (0.3%), pruritus (0.3%), urticaria (0.2%), somnolence (0.2%).
Danish: I kliniske studier med 1.723 patienter, der blev behandlet med intravenøs imipenem/cilastatin, var de hyppigst rapporterede systemiske bivirkninger, der i det mindste var muligt relateret til behandlingen: kvlame (2,0%), diarré (1,8%), opkastning (1,5%), udslæt (0,9%), feber (0,5%), hypotension (0,4%), krampeanfald (0,4%) (se pkt.
English: Central nervous system
Danish: Centralnervesystemet
English: Gram-negative aerobes:
Danish: Gram-positive aerober:
English: Do not freeze the reconstituted solution.
Danish: Den rekonstituerede opløsning må ikke nedfryses.
English: Greece: Primaxin
Danish: Grækenland: Primaxin
English: Following a single 250 mg/250 mg intravenous dose of TIENAM given 24 hours after haemodialysis, AUCs for imipenem and cilastatin were 3.7-fold and 16.4-fold higher, respectively, as compared to subjects with normal renal function.
Danish: Efter en enkelt intravenøs dosis TIENAM på 250 mg/250 mg indgivet 24 timer efter hæmodialyse var AUC for imipenem og cilastatin henholdsvis 3,7 gange og 16,4 gange højere sammenlignet med forsøgspersoner med normal nyrefunktion.
English: Individual urinary recoveries ranged from 5 to 40%, with an average recovery of 15-20% in several studies.
Danish: Ved indgift alene metaboliseres imipenem i nyrerne af dehydropeptidase-I. 5-40% genfandtes i urinen med et gennemsnit på 15-20 % i flere studier.
English: * A further proportionate reduction in dose administered must be made for patients with a body weight
Danish: * Yderligere proportional dosisreduktion skal foretages hos patienter med legemsvægt <70 kg.
English: Therefore, your doctor will decide whether you should use TIENAM while breast-feeding.
Danish: Deres læge vil derfor vurdere, om De kan bruge TIENAM, mens De ammer.
English: Antibiotic-associated colitis and pseudomembranous colitis have been reported with imipenem/cilastatin and with nearly all other anti-bacterial agents and may range from mild to life-threatening in severity.
Danish: Antibiotika-associeret kolit og pseudomembranøs kolit er set ved behandling med imipinem/cilastatin og med stort set alle andre antibiotika og kan i sværhedsgrad variere fra let til livstruende.
English: Concomitant use of an appropriate anti-MRSA agent may be indicated when MRSA infections are suspected or proven to be involved in the approved indications.
Danish: Samtidig anvendelse af et hensigtsmæssigt lægemiddel mod methicillin-resistente Staphylococcus aureas (MRSA) kan være indiceret, når MRSA-infektioner er mistænkt for eller påvist at være involveret i de godkendte indikationer.
English: Children TIENAM is not recommended in children less than one year of age or children with kidney problems.
Danish: TIENAM bør ikke gives til børn under 1 år eller børn med nyreproblemer.
English: In healthy elderly volunteers (65 to 75 years of age with normal renal function for their age), the pharmacokinetics of a single dose of TIENAM 500 mg/500 mg administered intravenously over 20 minutes were consistent with those expected in subjects with slight renal impairment for which no dose alteration is considered necessary.
Danish: Hos raske, ældre frivillige forsøgspersoner (65 - 75 år med normal nyrefunktion i forhold til alderen) svarede farmakokinetikken af en enkelt dosis TIENAM 500 mg/500 mg efter intravenøs administration over 20 minutter til den farmakokinetik, der kunne forventes hos forsøgspersoner med let nedsat nyrefunktion, hvor dosisjustering ikke ansås for at være nødvendig.
English: Patients with a creatinine clearance of ≤5 ml/min/1.73 m2
Danish: Patienter med kreatinin-clearance 5 ml/min/1,73 m2
English: • Inflammation of the colon with severe diarrhoea
Danish: • Betændelse i tyktarmen med alvorlig diarré
English: Both imipenem and cilastatin are cleared from the circulation during haemodialysis.
Danish: Både imipenem og cilastatin fjernes fra cirkulationen ved hæmodialyse.
English: • Severe loss of liver function due to inflammation (fulminant hepatitis)
Danish: • Alvorligt nedsat leverfunktion pga. betændelsestilstand (fulminant hepatitis)
English: IV.
Danish: i.v.
English: For patients with normal renal function (creatinine clearance of >70 ml/min/1.73 m2), the recommended dose regimens are:
Danish: Til patienter med normal nyrefunktion (kreatinin-clearance >70 ml/min/1,73 m2) anbefales følgende dosisregime:
English: It is important that you tell your doctor if you are breast-feeding or if you intend to breast-feed before receiving TIENAM.
Danish: Det er vigtigt, at De fortæller Deres læge, hvis De ammer eller forventer at amme før De bruger TIENAM.
English: Staphylococcus coagulase negative (Methicillin-susceptible) Streptococcus agalactiae
Danish: Staphylococcus aureus (methicillin-følsom)* Staphylococcus koagulasenegative (methicillin-følsom) Streptococcus agalactiae
English: Very rare pruritus vulvae
Danish: Pruritus vulvae
English: Each vial contains sodium bicarbonate equivalent to approximately 1.6 mEq of sodium (approximately 37.6 mg).
Danish: Et hætteglas indeholder natriumhydrogenkarbonat svarende til ca. 1,6 mEq natrium (ca. 37,6 mg).
English: These experiences have been reported most commonly in patients with CNS disorders (e.g. brain lesions or history of seizures) and/or compromised renal function in whom accumulation of the administered entities could occur.
Danish: Dette er hyppigst set hos patienter med lidelser i centralnervesystemet (f. eks. hjernelæsioner eller krampeanfald i anamnesen) og/eller hos patienter med nedsat nyrefunktion, hvor akkumulering af de indgivne lægemidler kan opstå.
English: Very rare cyanosis, tachycardia, palpitations
Danish: Cyanose, takykardi, palpitationer
English: Each dose >500 mg/500 mg should be infused over 40 to 60 minutes.
Danish: En dosis på >500 mg/500 mg skal indgives over 40 - 60 minutter.
English: Rare staining of teeth and/or tongue
Danish: Misfarvning af tænder og/eller tunge
English: ** When the 500 mg/500 mg dose is used in patients with creatinine clearances of 6 to 20 ml/min/l.73 m2,
Danish: ** Når TIENAM 500 mg/500 mg gives til patienter med kreatinin-clearance på 6 til 20 ml/min/1,73 m2
English: TIENAM should not be used during pregnancy unless your doctor decides the potential benefit justifies the potential risk to the foetus.
Danish: TIENAM må ikke anvendes under graviditet, medmindre Deres læge vurderer at den forventede fordel opvejer den mulige risiko for fostret.
English: TIENAM may be used in the management of patients with low white blood cell counts, who have fever that is suspected to be due to a bacterial infection.
Danish: TIENAM kan bruges til behandling af patienter med nedsat antal hvide blodceller (neutropeni) med feber, der mistænkes for at skyldes en bakteriel infektion.
English: There is no dose adjustment necessary (see section
Danish: Dosisjustering er ikke nødvendig (se pkt.
English: Pharmacokinetic/Pharmacodynamic (PK/PD) relationship Similar to other beta-lactam antibacterial agents, the time that imipenem concentrations exceed the MIC (T>MIC) has been shown to best correlate with efficacy.
Danish: I lighed med andre beta-lactam-antibiotika har den tid, hvor imipenemkoncentrationn overstiger MIC (T>MIC), vist sig at korrelere bedst med virkningen.
English: What TIENAM is and what it is used for Before you use TIENAM How to use TIENAM Possible side effects
Danish: Det skal De vide, før De begynder at bruge TIENAM Sådan skal De bruge TIENAM Bivirkninger
English: • Abnormal kidney, liver and blood function detected by blood tests
Danish: • Unormal nyre-, lever- og blodfunktion påvist via blodprøver
English: When treating patients with creatinine clearances of 5 ml/min/1.73 m2 who are undergoing dialysis use the dose recommendation for patients with creatinine clearances of 6 to 20 ml/min/1.73 m2 (see table 1).
Danish: Ved behandling af patienter med kreatinin-clearance 5 ml/min/1,73 m2, som er i dialyse, bør dosisforskrifterne for patienter med kreatinin-clearance 6-20 ml/min/1,73 m2 anvendes (se tabel 1).
English: Rare agranulocytosis
Danish: Agranulocytose
English: Others: Chlamydia spp.
Danish: Øvrige: Chlamydia spp.
English: Following a single 250 mg/250 mg intravenous dose of TIENAM, the area under the curve (AUCs) for imipenem increased 1.1-fold, 1.9-fold, and 2.7-fold in subjects with mild (Creatinine Clearance (CrCL) 50-80 ml/min/1.73 m2), moderate (CrCL 30-<50 ml/min/1.73 m2), and severe (CrCL <30 ml/min/1.73 m2) renal impairment, respectively, compared to subjects with normal renal function (CrCL >80 ml/min/1.73 m2), and AUCs for cilastatin increased 1.6-fold, 2.0-fold, and 6.2-fold in subjects with mild, moderate, and severe renal impairment, respectively, compared to subjects with normal renal function.
Danish: Efter en enkelt intravenøs dosis TIENAM på 250 mg/250 mg steg arealet under kurven (AUC) for imipenem 1,1 gange, 1,9 gange og 2,7 gange hos forsøgspersoner med henholdsvis let (kreatinin-clearance 50-80 ml/min/1,73 m2), moderat (kreatinin-clearance 30-<50 ml/min/1,73 m2) og svært (kreatininclearance <30 ml/min/1,73 m2) nedsat nyrefunktion, sammenlignet med forsøgspersoner med normal nyrefunktion (kreatinin-clearance >80 ml/min/1,73 m2).
English: • Red swollen tongue, overgrowth of the normal projections on the tongue giving it a hairy appearance,
Danish: • Rødlig opsvulmet tunge, forstørrelse af tungens struktur, der giver et behåret udseende, halsbrand,
English: • Severe hypersensitivity (e.g. anaphylactic reaction, severe skin reaction) to any other type of beta lactam antibacterial agent (e.g. penicillins or cephalosporins).
Danish: • Svær overfølsomhed (f.eks. anafylaktisk reaktion, svær hudreaktion) over for andre beta-lactam antibiotika (f.eks. penicilliner eller cefalosporiner).
English: HOW TO USE TIENAM
Danish: SÅDAN SKAL DE BRUGE TIENAM
English: The proportionate dose for patients <70 kg would be calculated by dividing the patient's actual body weight (in kg) by 70 kg multiplied by the respective dose recommended in Table 1.
Danish: Den proportionale dosis til patienter <70 kg beregnes ved at dividere patientens aktuelle legemsvægt (i kg)
English: For paediatric patients ≥1 year of age, the recommended dose is 15/15 or 25/25 mg/kg/dose administered every 6 hours.
Danish: Pædiatrisk population ≥1 år Den anbefalede dosis til pædiatriske patienter ≥1 år er 15/15 eller 25/25 mg/kg/dosis indgivet hver 6. time.
English: • Inflammation of intestine with bloody diarrhoea (haemorrhagic colitis)
Danish: • Betændelsestilstand i tarmen med blodig diaré (hæmoragisk colitis)
English: It kills a wide range of bacteria (germs) that cause infections in various parts of the body in adults and children one year of age and above.
Danish: Det bruges hos voksne og børn i alderen 1 år og derover til at dræbe et bredt spektrum af bakterier (mikroorganismer), der forårsager infektioner forskellige steder i kroppen.
English: Elderly population No dose adjustment is required for the elderly patients with normal renal function (see section 5.2).
Danish: Ældre Dosisjustering er ikke nødvendig hos ældre patienter med normal nyrefunktion (se pkt.
English: Uncommon fever, local pain and induration at the injection site, erythema at the injection site
Danish: Feber, lokal smerte og induration på injektionsstedet, erytem på injektionsstedet Ubehag i brystet, asteni/svaghed
English: Take special care with TIENAM
Danish: Vær ekstra forsigtig med at bruge TIENAM
English: Very rare haemorrhagic colitis, abdominal pain, heartburn, glossitis, tongue papilla hypertrophy, increased salivation
Danish: Hæmoragisk kolit, abdominalsmerter, halsbrand, glossit, hypertrofi af tungepapiller, øget spytsekretion
English: Furthermore, due to the limited susceptibility of specific pathogens associated with e.g. bacterial skin and soft-tissue infections, to imipenem/cilastatin, caution should be exercised.
Danish: Desuden skal der udvises forsigtighed på grund af visse patogeners begrænsede følsomhed for imipenem/cilastatin i forbindelse med f.eks. bakterielle hudog bløddelsinfektioner.
English: Rare encephalopathy, paraesthesia, focal tremor, taste perversion
Danish: Encefalopati, paræstesi, fokal tremor, smagsforstyrrelser
English: For infusion times see Method of administration.
Danish: Mht. infusionstider se Indgivelsesmåde.