FrancophonIA/ELRC3.0 huggingface dataset:
English: Two main studies in 435 patients with low levels of platelets due to long-standing liver disease found Doptelet effective at increasing platelet levels before an invasive procedure.
Croatian: U dvama glavnim ispitivanjima na 435 bolesnika s niskom razinom trombocita uslijed kronične bolesti jetre utvrđena je učinkovitost lijeka Doptelet s obzirom na povećanje broja trombocita prije invazivnog postupka.
English: Studies have found that Doptelet reduced the need for platelet transfusions or other rescue treatments to prevent excessive bleeding before an invasive procedure and for up to 7 days afterward.
Croatian: Ispitivanjima je utvrđeno da se primjenom lijeka Doptelet smanjuje potreba za transfuzijom trombocita ili drugim terapijama spasa radi sprječavanja prekomjernog krvarenja prije invazivnog postupka i do 7 dana nakon njega.
English: Any unwanted effects during treatment with Doptelet were thought to result from patients' medical condition and the nature of the invasive procedure for which it was used.
Croatian: Utvrđeno je da su sve nuspojave terapije lijekom Doptelet posljedica zdravstvenog stanja bolesnika i prirode invazivnog postupka za koji se lijek koristio.
English: The active substance in Doptelet, avatrombopag, attaches to the same receptors as thrombopoietin, helping to increase the platelet count.
Croatian: Djelatna tvar lijeka Doptelet, avatrombopag, veže se na iste receptore kao i trombopoetin i tako doprinosi povećanju broja trombocita.
English: What benefits of Doptelet have been shown in studies?
Croatian: Koje su koristi od lijeka Doptelet utvrđene u ispitivanjima?
English: The platelet count increased in patients treated with Doptelet.
Croatian: Broj trombocita porastao je u bolesnika koji su primali lijek Doptelet.
English: For the full list of side effects and restrictions with Doptelet, see the package leaflet.
Croatian: Potpuni popis nuspojava i ograničenja povezanih s lijekom Doptelet potražite u uputi o lijeku.
English: In the body, a hormone called thrombopoietin stimulates the production of platelets by attaching to receptors (targets) in the bone marrow.
Croatian: Hormon trombopoetin potiče stvaranje trombocita u tijelu vezivanjem na određene receptore (ciljna mjesta) u koštanoj srži.
English: Doptelet contains the active substance avatrombopag.
Croatian: Doptelet sadržava djelatnu tvar avatrombopag.
English: How does Doptelet work?
Croatian: Kako djeluje Doptelet?
English: How is Doptelet used?
Croatian: Kako se Doptelet primjenjuje?
English: The main measure of effectiveness was the number of patients who did not require a transfusion of platelets or other treatment ('rescue procedure') to prevent excessive bleeding after starting Doptelet treatment and for up to 7 days after their invasive procedure.
Croatian: trombocita ni bilo koji drugi postupak („terapija spasa”) radi sprječavanja prekomjernog krvarenja nakon početka primjene lijeka Doptelet te do 7 dana nakon invazivnog postupka.
English: Member State EU/EEA
Croatian: Države članice EUa/EGP-a
English: Tylosin is not used in human medicine.
Croatian: Tilozin se ne upotrebljava u humanoj medicini.
English: Thus, it cannot be expected that data concurring with current
Croatian: Stoga se ne može očekivati da će biti dostupni podatci koji se natječu
English: 53000 LAVAL France
Croatian: 53000 LAVAL Francuska
English: Treatment durations beyond three weeks
Croatian: Trajanje liječenja dulje od tri tjedna
English: It is ineffective against Enterobacteriaceae.
Croatian: Ne djeluje protiv Enterobacteriaceae.
English: 949 01 Nitra Slovakia
Croatian: 949 01 Nitra Slovačka
English: A recent report from Spain (Alvarez et al. (2013))
Croatian: Nedavno izvješće iz Španjolske (Alvarez et al. (2013.))
English: 92521 Neuilly sur Seine cedex France
Croatian: 92521 Neuilly sur Seine cedex Francuska
English: Product name
Croatian: Naziv proizvoda
English: Przedsiębiorstwo Farmaceutyczne Okoniewscy "VETOS FARMA" Sp. z o.o.
Croatian: Przedsiębiorstwo Farmaceutyczne Okoniewscy "VETOS FARMA" Sp. z o.o. ul.
English: 3, Vyt and Hommez (2006) 4, MARAN (2008)
Croatian: 3, Vyt ai Hommez (2006.) 4, MARAN (2008.)
English: 66-400 Gorzów Wielkopolski Poland
Croatian: 66-400 Gorzów Wielkopolski Poljska
English: It is active mostly against Gram-positive bacteria and mycoplasmas.
Croatian: Djeluje uglavnom protiv Gram-pozitivnih bakterija i mikoplazmi.
English: 1ere avenue 2065 m L. I. D. 06516 Carros
Croatian: Francuska VIRBAC 1ere avenue 2065 m L. I. D. 06516 Carros
English: Resistance is caused by point mutations of 23S rDNA.
Croatian: Rezistencija je uzrokovana točkastim mutacijama podjedinice 23S rDNK.
English: S.C. PASTEUR -FILIALA FILIPESTI
Croatian: Rumunjska S.C. PASTEUR -FILIALA FILIPESTI
English: The cause for the high resistance rate can be found in the mechanisms governing the development of non-horizontal transferable resistance.
Croatian: Uzrok za visoku stopu rezistencije može se naći u mehanizmima koji upravljaju razvojem nevodoravno prenosive rezistencije.
English: (EMA/CVMP/SAGAM/741087/2009) mentions with support from data from FINRES-Vet (1999) 2, SVARM
Croatian: (EMA/CVMP/SAGAM/741087/2009) napominje uz potporne podatke iz FINRES-Vet (1999.) 2, SVARM
English: Risk management or mitigation measures
Croatian: Upravljanje rizikom ili mjere za smanjenje rizika
English: IRIS Mednarodna trgovina d.o.o.,
Croatian: Slovenija IRIS Mednarodna trgovina d.o.o.,
English: 200 AVENUE DE MAYENNE ZONE INDUSTRIELLE DES TOUCHES
Croatian: Francuska SOGEVAL 200 AVENUE DE MAYENNE ZONE INDUSTRIELLE DES TOUCHES
English: It may be administered by oral or parenteral routes.
Croatian: Može se primjenjivati peroralno ili parenteralno.
English: ZONE D'ACTIVITES DU BOIS DE TEILLAY
Croatian: Francuska DELTAVIT ZONE D'ACTIVITES DU BOIS DE TEILLAY
English: Crida Pharm SRL str. Intrarea Vagonetului nr.2, bl.101, ap.47, parter, sector 6 Bucharest
Croatian: Rumunjska Crida Pharm SRL str. Intrarea Vagonetului nr.2, bl.101, ap.47, parter, sector 6 Bucharest
English: Dzierżoniowska 21 58-260 Bielawa Poland
Croatian: Dzierżoniowska 21 58-260 Bielawa Poljska
English: 28108 Alcobendas (Madrid) Spain
Croatian: 28108 Alcobendas (Madrid) Španjolska
English: 12030 Cavallermaggiore (CN) Italy
Croatian: 12030 Cavallermaggiore (CN) Italija
English: 42010 Rio Saliceto (RE) Italy
Croatian: 42010 Rio Saliceto (RE) Italija
English: Kalinovica, 10436 Rakov Potok Croatia
Croatian: Kalinovica, 10436 Rakov Potok Hrvatska
English: In this situation it is not to be expected that scientifically well founded justifications for treatment durations can be obtained from the different marketing authorisation holders for different indications for pigs.
Croatian: U ovakvoj situaciji nije za očekivati da se znanstveno dobro utemeljeno opravdanje za trajanja liječenja mogu pridobiti od strane različitih nositelja odobrenja za različite indikacije za svinje.
English: 4.2 Indications for use, specifying the target species
Croatian: 4.2. Indikacije za uporabu, određivanje ciljanih vrsta životinja
English: D-61352 Bad Homburg Germany
Croatian: D-61352 Bad Homburg Njemačka
English: 16 Aleia Vazrajdane str., ap.42 Bulgaria
Croatian: 16 Aleia Vazrajdane str., ap.42 Bugarska
English: 1, the CVMP recommendations on macrolides state that ‘there might be a need to review certain SPCs to reduce the approved treatment duration in cases where it is found unnecessarily long in relation to the severity of the disease'.
Croatian: 1, preporuke CVMP o makrolidima navode da „može postojati potreba za pregledom određenih sažetaka svojstava proizvoda kako bi se smanjilo odobreno trajanje liječenja u slučajevima gdje je pronađeno da je to trajanje nepotrebno dugo u odnosu na težinu bolesti”.
English: V. del Commercio 28/30 41012 Carpi (MO) Italy
Croatian: V. del Commercio 28/30 41012 Carpi (MO) Italija
English: LABORATORIOS CALIER, S.A. BARCELONÉS, 26.
Croatian: Španjolska LABORATORIOS CALIER, S.A. BARCELONÉS, 26.
English: The general acceptance of the fact that antimicrobial treatment needs always to be combined with appropriate management and sanitary measures on the farm, to prevent the further spread of any particular microbe and thus reduce the risk for new clinical cases, makes it difficult to defend a need for very long treatment periods.
Croatian: Opća prihvaćenost činjenice da antimikrobno liječenje treba uvijek kombinirati s odgovarajućim upravljanjem i sanitarnim mjerama na poljoprivrednom gospodarstvu kako bi se spriječilo daljnje širenje bilo kojeg potencijalnog mikroorganizma i tako smanjio rizik od novih kliničkih slučajeva, čini teškom obranu potrebe za vrlo dugim razdobljima liječenja.
English: Via A. Diaz 147/149
Croatian: Diaz 147/149
English: These products are effective medicines for the treatment of several diseases such as respiratory disease and ileitis/porcine intestinal adenopathy (caused by Lawsonia intracellularis).
Croatian: Ti lijekovi su djelotvorni lijekovi za liječenje nekoliko bolesti poput respiratorne bolesti i ileitisa/svinjske crijevne adenopatije (uzrokovane bakterijom Lawsonia intracellularis).
English: As macrolides are critically important antimicrobials for pigs, unnecessary exposure leading to further resistance in target animal pathogens would be a serious risk to animal health.
Croatian: S obzirom da su makrolidi iznimno važni antimikrobni lijekovi za svinje, nepotrebno izlaganje koje vodi do daljnje rezistencije ciljnih životinjskih patogena bio bi ozbiljan rizik za zdravlje životinja.
English: Vetoquinol Biowet Sp. z o.o.
Croatian: Vetoquinol Biowet Sp. z o.o. ul.
English: LABORATOIRES BIOVE 3 RUE DE LORRAINE 62510 ARQUES France
Croatian: Francuska LABORATOIRES BIOVE 3 RUE DE LORRAINE 62510 ARQUES
English: Via A. Gramsci, 731-733 50019 Sesto Fiorentino (IT) Italy
Croatian: Via A. Gramsci, 731-733 50019 Sesto Fiorentino (IT) Italija
English: ANDRES PINTALUBA, S.A. Pol. Industrial Agro-Reus c/ Prudenci Bertrana 5.
Croatian: Španjolska ANDRES PINTALUBA, S.A. Pol. Industrial Agro-Reus c/ Prudenci Bertrana 5.
English: Sperling D, Smola J and Cizek A. 2011.
Croatian: P 82. Sperling D, Smola J and Cizek A. 2011.
English: For products where any specific treatment duration shorter than 3 weeks is recommended this should be maintained in the product information.
Croatian: Za lijekove kod kojih se preporučuje bilo kakvo liječenje u trajanju kraćem od 3 tjedna to treba uključiti u informacije o proizvodu.
English: SC Delos Impex 96 SRLStr Horia, Closca si Crisan, Otopeni judetul Ilfov
Croatian: Rumunjska SC Delos Impex 96 SRLStr Horia, Closca si Crisan, Otopeni judetul Ilfov
English: Special precautions for use in animals
Croatian: Posebne mjere opreza za uporabu na životinjama
English: AniMed Service AG Liebochstrasse 9 8143 Dobl Austria
Croatian: AniMed Service AG Liebochstrasse 9 8143 Dobl Austrija
English: However, effective alternatives are available (e.g. pleuromutilins) and, as there are very few susceptible outbreaks, the risk for inadequate treatment is deemed to outweigh the possible benefit of an additional treatment option in the unlikely event of confirmed susceptibility.
Croatian: Međutim dostupne su djelotvorne alternative (primjerice, pleuromutilini) i s obzirom da je bilo vrlo malo susceptibilnih izbijanja bolesti, smatra se da rizik od neodgovarajućeg liječenja nadmašuje moguću korist mogućnosti dodatnog liječenja u malo vjerojatnom slučaju potvrđene susceptibilnosti.
English: 17170 Amer (Girona) Spain
Croatian: 17170 Amer (Girona)
English: 18-421 Kownaty Poland
Croatian: 18-421 Kownaty Poljska
English: Denmark ScanVet Animal Health A/S Kongevejen 66
Croatian: ScanVet Animal Health A/S Kongevejen 66
English: The CVMP was asked to conclude on whether the duration of treatment with veterinary medicinal products containing tylosin beyond three weeks is justified and whether these products are still effective against swine dysentery caused by B. hyodysenteriae.
Croatian: Od CVMP-a je zatraženo da zaključi o tome je li trajanje liječenja veterinarsko-medicinskim proizvodom koji sadrži tilozin dulje od tri tjedna opravdano i da li su ti proizvodi još uvijek djelotvorni protiv svinjske dizenterije uzrokovane bakterijom B. hyodysenteriae.
English: Therefore, on 30 October 2013, Sweden presented to the Agency a referral notification under Article 35 of Directive 2001/82/EC for veterinary medicinal products containing tylosin to be administered orally via feed or the drinking water to pigs.
Croatian: Stoga je 30. listopada 2013. godine Švedska prezentirala Agenciju obavijest o arbitraži u skladu s člankom 35. Direktive 2001/82/EK za veterinarsko-medicinski proizvod koji sadrži tilozin koji se daje svinjama peroralno putem krmiva ili vode za piće.
English: To maintain oral tylosin as an efficacious treatment for other currently authorised indications for pigs, unnecessary exposure should be avoided.
Croatian: Za održavanje peroralnog tilozina kao djelotvornog liječenja za druge trenutno odobrene indikacije za svinje treba izbjegavati nepotrebno izlaganje.
English: Ipswich, Suffolk, IP7 6RD United Kingdom
Croatian: Ipswich, Suffolk, IP7 6RD Ujedinjena Kraljevina
English: Similarly, almost complete in vitro resistance was reported among 32 Brachyspira isolates from the Czech Republic (Sperling et al. (2011))
Croatian: Slično tome, gotovo potpuna rezistencija in vitro prijavljena je kod 32 izolata bakterije Brachyspira iz Češke Republike (Sperling et al. (2011.))
English: Since for B. hyodysenteriae the rRNA operon exists in a single copy one single base mutation is sufficient to achieve macrolide resistant clones (Zuerner and Stanton (1994)
Croatian: S obzirom da operon za B. hyodysenteriaeKrRNA operon postoji u jednoj kopiji temeljne baze, mutacija je dostatna za postizanje klonova rezistetnih na makrolid (Zuerner and Stanton (1994.)
English: In contrast, premix formulations authorised for the treatment and prevention of ileitis (caused by Lawsonia intracellularis) most often recommend treatment for not longer than up to three weeks.
Croatian: Nasuprot tome, formulacije predmješavine odobrene za liječenje i prevenciju ileitisa (uzrokovanog bakterijom Lawsonia intracellularis) najčešće preporučuju maksimalno trajanje liječenja od tri tjedna.
English: Extended and vaguely defined treatment periods present a risk from resistance perspective and would not be justifiable from a scientific point of view taking into account disease epidemiology as well as current awareness regarding the need to always combine antibiotic use with appropriate sanitary measures.
Croatian: Produljena i nejasno definirana razdoblja liječenje predstavljaju rizik od rezistencije i ne bi ih se moglo opravdati sa znanstvenog stajališta uzimajući u obzir epidemiologiju bolesti kao i trenutnu svijest o potrebi za stalnom kombinacijom uporabe antibiotika s odgovarajućim sanitarnim mjerama.
English: Oral tylosin has had widespread use in pig farming in many EU Member States for decades to treat and prevent disease and before entry into force of Regulation (EC) No 1831/2003, as a growth promoter.
Croatian: Peroralni tilozin ima raširenu uporabu na poljoprivrednim gospodarstvima koja se bave svinjogojstvom u mnogim državama članicama EU-a tijekom mnogih desetljeća za liječenje i prevenciju bolesti i prije stupanja na snagu Uredbe (EK) br. 1831/2003 kao promotor rasta.
English: 4600 Wels Austria
Croatian: 4600 Wels Austrija
English: Oral tylosin is regarded as an effective medicine against several diseases in pigs.
Croatian: Peroralni tilozin je djelotvoran lijek protiv nekoliko bolesti u svinja.
English: The potential risk for resistance development is evident through the current resistance situation of B. hyodysenteriae.
Croatian: Potencijalni rizik od razvoja rezistencije očit je trenutačnom situacijom rezistencije na B. hyodysenteriae.
English: To limit the selection pressure for bacteria unnecessary use should be avoided.
Croatian: Potrebno je izbjegavati nepotrebnu uporabu kako bi se ograničio pritisak odabira na bakteriju.
English: D-48308 Senden-Bösensell Germany
Croatian: D-48308 Senden-Bösensell Njemačka
English: Via Don Eugenio Servadei 16 47122 Forlì, Forlì-Cesena Italy
Croatian: Via Don Eugenio Servadei 16 47122 Forlì, Forlì-Cesena Italija
English: It is acknowledged that for certain holdings where susceptibility of B. hyodysenteriae to tylosin is still evident a removal of this indication would restrict the availability of treatment options.
Croatian: Potvrđeno je da bi za određena poljoprivredna gospodarstva u kojima je susceptibilnost B. hyodysenteriae na tilozin još uvijek očita, uklanjanje ove indikacije ograničilo dostupnost mogućnostima liječenja.
English: 43206 Reus (Tarragona) Spain
Croatian: 43206 Reus (Tarragona) Španjolska
English: Zavet JSC 5 Kiril i Metodii Str. Zavet
Croatian: Bugarska Zavet JSC 5 Kiril i Metodii Str.
English: DK-3480 Fredensborg Denmark
Croatian: DK-3480 Fredensborg Danska
English: Extended exposure of tylosin to pigs is related to risk for development of antimicrobial resistance.
Croatian: Produljeno izlaganje tilozinu u svinja povezano je s rizikom od razvoja antimikrobne rezistencije.
English: A similar treatment strategy is recommended for tylosin premix formulation for the treatment of swine dysentery where it is mentioned that treatment can be continued ‘until the end of risk', ‘as long as necessary' or ‘until slaughter'.
Croatian: Slična strategija liječenja preporučuje se za formulaciju predmješavine tilozina za liječenje svinjske dizenterije gdje je spomenuto da se liječenje može nastaviti „sve do kraja rizika” i „koliko god je to potrebno” ili „do klanja životinje”.
English: Possibly in part due to this, currently for the same indication and the same oral formulation there is significant variation between products regarding the recommended treatment duration for pigs.
Croatian: Moguće da je i to djelomični razlog što trenutačno za istu indikaciju i istu peroralnu formulaciju postoji značajna razlika između lijekova u odnosu na preporučeno trajanje liječenja za svinje.
English: Proceeding, Spirochaete Conference, 5-6 September 2013, UK. P 47
Croatian: Proceeding, Spirochaete Conference, 5-6 September 2013, UK.
English: Although the resistance situation has not been investigated in every country where tylosin is used against swine dysentery, the awareness that tylosin resistance develops quickly and the bulk of in vitro data covering many field isolates from different areas provide sufficient information to conclude that it cannot be expected that the efficacy rate is sufficient to warrant an indication for treatment and prevention of this disease.
Croatian: Iako situacija s rezistencijom nije ispitivana u svakoj državi u kojoj se tilozin koristi protiv svinjske dizenterije, svijest da se rezistencija na tilozin razvija brzo i neobrađeni in vitro podaci koji pokrivaju područja mnogih izolata iz različitih područja daju dovoljno informacija za zaključak da nije moguće očekivati da je stopa djelotvornosti dostatna da zajamči indikaciju za liječenje i prevenciju ove bolesti.
English: Although a somewhat lower rate of resistance was noted in Swedish strains collected during 1990-2010, more than 75% of the isolates demonstrate a minimum inhibitory concentration (MIC) far above the proposed epidemiological cut-off value of >16 μg/ml (Pringle et al. (2012))
Croatian: Iako je zabilježena nešto niža stopa rezistencije kod izolata švedskih sojeva prikupljenih tijekom 1990.-2010., više od 75 % izolata pokazalo je minimalne inhibitorne koncentracije (MIK) daleko više od predloženi epidemioloških presječnih vrijednosti od >16 μg/ml (Pringle et al.
English: Whereas:
Croatian: S obzirom na navedeno:
English: Taking efficacy aspects as well as the risk for resistance emergence into account, a maximum treatment period of three weeks applying the same dose level throughout the treatment period is regarded appropriate independent of disease;
Croatian: Uzimajući u obzir aspekte djelotvornosti kao i rizik od nastanka rezistencije, najdulje trajanje liječenja od tri tjedna uz primjenu iste razine doze tijekom razdoblja liječenja smatra se odgovarajućim neovisno o vrsti bolesti;
English: Biovet JSC 39 Petar Rakov Str 4550 Peshtera Bulgaria
Croatian: Bugarska Biovet JSC 39 Petar Rakov Str 4550 Peshtera Bugarska
English: Anupco LTd.
Croatian: Rumunjska Anupco LTd.
English: Sensitivity and resistance of Brachyspira species and consequences for global swine/poultry production.
Croatian: Thomson J. 2013. Sensitivity and resistance of Brachyspira species and consequences for global swine/poultry production.
English: th international conference on colonic spirochaetal infections in animals and humans in the United Kingdom in September 2013, it was mentioned in a key note that: “tylosin has been rendered totally ineffective through widespread use for in-feed medication over the years” (Thomson (2013))
Croatian: U skladu s ovim opažanjima, tijekom 6. međunarodne konferencije o crijevnim infekcijama spirohetama u životinja i ljudi u Ujedinjenoj Kraljevini u rujnu 2013. u glavnom izlaganju zabilježeno je sljedeće: „tilozin se pokazao potpuno nedjelotvoran u široj uporabi u ljekovitoj hrani za životinje tijekom godina” (Thomson (2013.))
English: D-30625 Hannover Germany
Croatian: D-30625 Hannover Njemačka
English: With regard to respiratory disease in pigs, tylosin premix formulations are currently often authorised for treatment using a higher dose for the first two to three weeks of treatment followed by a lower dose (typically 40% of the initial dose) for an extended period of time, often stated as the ‘whole risk period'.
Croatian: S obzirom na bolest u svinja, formulacije predmješavine tilozina trenutačno se često odobravaju za liječenje uporabom viših doza za prva dva do tri tjedna liječenja nakon čega slijedi niža doza (obično iznosi 40 % od početne doze) tijekom produljenog vremenskog razdoblja, često se navodi kao „razdoblje punog rizika”.
English: Specific treatment recommendations shorter than 3 weeks should be maintained.
Croatian: Potrebno je održati specifične preporuke za liječenje kraće od 3 tjedna.
English: Tylosin is a macrolide antibiotic which is produced by Streptomyces fradiae.
Croatian: Tilozin je makrolidni antibiotik koji proizvode bakterije Streptomyces fradiae.
English: The excessive use over time may explain the high proportion of resistance in B. hyodysenteriae strains, the cause for swine dysentery, reported from many European countries today.
Croatian: Prekomjerna uporaba tijekom vremena može objasniti visoki udio rezistencije na sojeve B. hyodysenteriae, uzrok svinjske dizenterije, o čemu trenutačno izvješćuju brojne europske države.
English: 2730 HERLEV Denmark
Croatian: 2730 HERLEV Danska
English: SPECIAL WARNING(S)
Croatian: POSEBNO UPOZORENJE(A)
English: Pol J Vet Sci 15, No. 2, 259-265 Alvarez LF, Martinez-Lobo J, Aller L M, Naharro G, Carvajal A, Rubio P. 2013.
Croatian: 2, 259-265 Alvarez LF, Martinez-Lobo J, Aller L M, Naharro G, Carvajal A, Rubio P. 2013.
English: For similar reasons recommendations to reduce the initial dose for an extended treatment period are not acceptable.
Croatian: Iz sličnih razloga nisu prihvatljive preporuke za smanjivanjem početne doze za produljeno razdoblje liječenja.
English: It is acknowledged that many oral tylosin formulations for pigs currently available on the EU market have been authorised many years ago, according to posology justification standards regarded acceptable at that time and in the context of what was then regarded as acceptable strategies for the administration of antimicrobials.
Croatian: Potvrđeno je da su mnoge peroralne formulacije tilozina za svinje koje su trenutno dostupne na tržištu EU odobrene prije puno godina i da su se u skladu sa standardima za opravdavanje doziranja smatrale u to vrijeme prihvatljivim te u kontekstu onoga što se tada smatralo prihvatljivim strategijama za primjenu antimikrobnih lijekova.
English: "Veta" Mariusz Hołownia
Croatian: P.F.H.U. "Veta" Mariusz Hołownia