FrancophonIA/ELRC3.0 huggingface dataset:
English: Body surface area (m2)
Croatian: Površina tijela (m2)
English: The potential risk for humans is unknown.
Croatian: Potencijalni rizik za ljude je nepoznat.
English: Yargesa can be taken with or without food.
Croatian: Yargesa se može uzeti s hranom ili bez nje.
English: In such case, your doctor may decide to conduct further investigations.
Croatian: U tom slučaju Vaš liječnik može odlučiti o provođenju daljnjih pretraga.
English: These effects may be partly related to maternal toxicity.
Croatian: Ti učinci mogu djelomično biti povezani s toksičnošću kod majke.
English: The greatest prevalence was observed between 6 and 12 months.
Croatian: Najveća prevalencija primijećena je između 6 i 12 mjeseci.
English: The mechanism for this effect is unknown.
Croatian: Mehanizam za taj učinak nije poznat.
English: Your doctor will tell you how long your treatment will last.
Croatian: Liječnik će Vam reći koliko će dugo trajati liječenje.
English: Most cases are mild and disappear quite quickly.
Croatian: U većini slučajeva su blage i brzo nestaju.
English: In case of overdose general medical care is recommended.
Croatian: U slučaju predoziranja preporučuje se opća medicinska skrb.
English: It is used to treat two conditions:
Croatian: Primjenjuje se za liječenje dvije bolesti:
English: People usually stop losing weight as treatment goes on.
Croatian: Ljudi obično prestanu gubiti na težini kako se liječenje nastavlja.
English: A relevance of these findings to humans cannot be excluded.
Croatian: Važnost ovih nalaza za ljude se ne može isključiti.
English: To remove the capsule:
Croatian: Za vađenje kapsule:
English: NN: {number}
Croatian: NN: {broj}
English: They may lower the amount of Yargesa in your body.
Croatian: To može sniziti količinu lijeka Yargesa u Vašem tijelu.
English: It starts to build up in certain cells of the body's immune system.
Croatian: Počinje se nakupljati u nekim stanicama imunološkog sustava tijela.
English: If you have a problem with your kidneys you may receive a lower starting dose.
Croatian: Ako imate poteškoće s bubrezima možete primati nižu početnu dozu.
English: Effects on spermatogenesis
Croatian: Djelovanje na spermatogenezu
English: Do not throw away any medicines via wastewater or household waste.
Croatian: Nikada nemojte nikakve lijekove bacati u otpadne vode ili u kućni otpad.
English: Maximum plasma concentrations are reached about 2 hours after dose.
Croatian: Maksimalne koncentracije u plazmi dostignute su u roku od oko 2 sata nakon doze.
English: SN: {number}
Croatian: SN: {broj}
English: UNIQUE IDENTIFIER - HUMAN READABLE DATA PC: {number}
Croatian: JEDINSTVENI IDENTIFIKATOR - PODACI ČITLJIVI LJUDSKIM OKOM PC: {broj}
English: The tremor often disappears without needing to stop the treatment.
Croatian: Tremor često nestaje bez potrebe za prekidom liječenja.
English: Do not stop taking Yargesa without talking to your doctor.
Croatian: Nemojte prestati uzimati lijek Yargesa bez razgovora s liječnikom.
English: The Netherlands
Croatian: Nizozemska
English: At present, there is insufficient clinical experience in these patients to provide dosing recommendations.
Croatian: Trenutačno nema dovoljno kliničkog iskustva s takvim bolesnicima za davanje preporuka za doziranje.
English: Recommended dose 200 mg three times a day 200 mg twice a day 100 mg three times a day 100 mg twice a day 100 mg once a day
Croatian: Preporučena doza 200 mg triput dnevno 200 mg dvaput dnevno 100 mg triput dnevno 100 mg dvaput dnevno 100 mg jednom dnevno
English: Miglustat crosses the placenta and should not be used during pregnancy.
Croatian: Miglustat prolazi kroz placentu i ne smije se uzimati tijekom trudnoće.
English: Patients with chronic diarrhoea or other persistent gastrointestinal events that do not respond to these interventions should be investigated according to clinical practice.
Croatian: Bolesnike s kroničnim proljevom ili drugim perzistirajućim gastrointestinalnim događajima koji ne reagiraju na te intervencije treba pregledati u skladu s kliničkom praksom.
English: These effects occurred at exposure levels similar to those in patients, but showed reversibility.
Croatian: Ovi su se učinci javili pri razinama izloženosti sličnim onima kod bolesnika, ali su bili reverzibilni.
English: Do not take Yargesa - if you are allergic to miglustat or any of the other ingredients of this medicine (listed in section 6)
Croatian: Nemojte uzimati lijek Yargesa - ako ste alergični na miglustat ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.)
English: The terminal half-life of radioactivity in plasma was 150 h suggesting the presence of one or more metabolites with very long half-life.
Croatian: Terminalni poluvijek radioaktivnosti u plazmi bio je 150 sati, što ukazuje na prisutnost jednog ili više metabolita s vrlo dugim poluvijekom.
English: Dose reduction may ameliorate the tremor, usually within days, but discontinuation of treatment may sometimes be required.
Croatian: Smanjenje doze može umanjiti tremor, obično u nekoliko dana, ali ponekad može biti potrebno prekinuti liječenje.
English: UNIQUE IDENTIFIER - 2D BARCODE 2D barcode carrying the unique identifier included.
Croatian: 17. JEDINSTVENI IDENTIFIKATOR - 2D BAR KOD <Sadrži 2D bar kod s jedinstvenim identifikatorom.>
English: If you are pregnant, breast feeding, think you may be pregnant or planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Croatian: Ako ste trudni ili dojite, mislite da biste mogli biti trudni ili planirate imati dijete, obratite se svom liječniku ili ljekarniku za savjet prije nego uzmete ovaj lijek.
English: A No Observed Effect Level (NOEL) was not established and the effect was not dose dependent.
Croatian: Razina bez opaženog učinka (NOEL - No Observed Effect Level) nije ustanovljena i učinak nije bio ovisan o dozi.
English: Liver volume (primary efficacy variable) was unchanged from baseline to the end of treatment.
Croatian: Volumen jetre (primarna varijabla djelotvornosti) bio je nepromijenjen od početka do kraja liječenja.
English: No acute symptoms of overdose have been identified.
Croatian: Nisu uočeni akutni simptomi predoziranja.
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 22 March 2017
Croatian: Datum prvog odobrenja: 22 Ožujak 2017
English: - the active substance is miglustat.
Croatian: - djelatna tvar je miglustat.
English: What Yargesa looks like and contents of the pack
Croatian: Kako Yargesa izgleda i sadržaj pakiranja
English: If you do lose some weight when you start treatment with Yargesa don't worry.
Croatian: Ako izgubite na težini kad počnete liječenje lijekom Yargesa, ne brinite.
English: You should not take Yargesa if you are pregnant or thinking of becoming pregnant.
Croatian: Lijek Yargesa ne smijete uzeti ako ste trudni ili ako namjeravate zatrudnjeti.
English: Apparent oral clearance (CL/F) is 230 ± 39 ml/min.
Croatian: Prividan peroralni klirens (CL/F) je 230 ± 39 ml/min.
English: What Yargesa is and what it is used for
Croatian: Što je Yargesa i za što se koristi
English: Mechanistic studies revealed a rat specific mechanism which is considered to be of low relevance for humans.
Croatian: Ispitivanja mehanizma otkrila su specifičan mehanizam u štakora koji se smatra od male važnosti za ljude.
English: In healthy subjects miglustat is rapidly absorbed.
Croatian: Kod zdravih se osoba miglustat brzo apsorbirao.
English: Your doctor may reduce your dose, e.g., to one capsule (100 mg) once or twice a day, if you suffer from diarrhoea when taking Yargesa (see section 4).
Croatian: Liječnik može smanjiti Vašu dozu, npr. na jednu kapsulu (100 mg) jednom ili dvaput dnevno, ako imate proljev dok uzimate lijek Yargesa (vidjeti dio 4).
English: The systemic exposure at the lowest dose was below or comparable to that observed in humans (based on AUC0-∞) at the recommended human dose.
Croatian: Sistemska izloženost pri najnižoj dozi bila je niža ili se mogla usporediti s onom zapaženom kod ljudi (na osnovu AUC0-∞) pri preporučenoj dozi za ljude.
English: Tell your doctor if you are taking medicines containing imiglucerase, which are sometimes used at the same time as Yargesa.
Croatian: Obavijestite svog liječnika ako uzimate lijekove koji sadrže imiglucerazu, koji se ponekad uzimaju istodobno s lijekom Yargesa.
English: Absolute bioavailability has not been determined.
Croatian: Nije utvrđena apsolutna bioraspoloživost.
English: For the full list of excipients, see section 6.1.
Croatian: Za cjeloviti popis pomoćnih tvari, vidjeti dio 6.1.
English: Most patients get one or more of these side effects, usually at the start of treatment or at intervals during treatment.
Croatian: Kod većine bolesnika dođe do jedne ili više tih nuspojava, obično na početku liječenja ili u razmacima tijekom liječenja.
English: Leukopenia and neutropenia have also been observed in a similar group of patients receiving 800 mg/day or higher dose.
Croatian: Leukopenija i neutropenija također su primijećene u sličnoj skupini bolesnika koji su primali dozu od 800 mg/dan ili višu.
English: The tests will help the doctor decide whether these effects are due to your disease or other existing conditions, or due to side effects of Yargesa (see section 4 for further details).
Croatian: Ove pretrage će pomoći liječniku ustanoviti jesu li ti učinci posljedica ove bolesti ili drugih postojećih bolesti ili su posljedica nuspojava lijeka Yargesa (za daljnje pojedinosti vidjeti dio 4).
English: What Yargesa contains
Croatian: Što Yargesa sadrži
English: Common effects - may affect up to 1 in 10 people
Croatian: Česte nuspojave - mogu se javiti kod manje od 1 na 10 osoba
English: MARKETING AUTHORISATION NUMBER(S) EU/1/17/1176/001
Croatian: BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/17/1176/001
English: Thirteen patients discontinued treatment due to an adverse event.
Croatian: Trinaest bolesnika je liječenje prekinulo zbog štetnih događaja.
English: If you get a slight tremor, usually trembling hands, seek medical advice from your doctor as soon as possible.
Croatian: Ako imate blagi tremor, obično drhtanje ruku, zatražite savjet svog liječnika što je prije moguće.
English: Pharmacotherapeutic group: Other alimentary tract and metabolism products, ATC Code: A16AX06
Croatian: Farmakoterapijska skupina: Drugi lijekovi za probavni sustav i metabolizam, ATK oznaka: A16AX06
English: There are no adequate data from the use of miglustat in pregnant women.
Croatian: Nema odgovarajućih podataka o primjeni miglustata u trudnica.
English: Carcinomas in the large intestine occurred occasionally at all doses with a statistically significant increase in the high dose group.
Croatian: Karcinomi debelog crijeva javljali su se povremeno pri svim dozama, uz statistički značajno povećanu učestalost u skupini s visokom dozom.
English: Yargesa has negligible influence on the ability to drive and use machines.
Croatian: Yargesa zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Regular monitoring of vitamin B12 level is recommended because of the high prevalence of vitamin B12 deficiency in patients with type 1 Gaucher disease.
Croatian: Preporučuje se redovito praćenje razine vitamina B12 zbog visoke prevalencije nedostatka vitamina B12 u bolesnika s Gaucherovom bolesti tipa 1.
English: Six patients had miglustat treatment prematurely discontinued for potential disease worsening, as defined in the study.
Croatian: Šest bolesnika je liječenje miglustatom prekinulo ranije zbog mogućeg pogoršanja bolesti, kako je definirano u ispitivanju.
English: Adverse reactions from clinical trials and spontaneous reporting, occurring in >1% of patients, are listed in the table below by system organ class and frequency (very common: ≥ 1/10, common: ≥ 1/100 < 1/10, uncommon: ≥1/1,000 to <1/100, rare: ≥1/10,000 to <1/1,000, very rare: <1/10,000).
Croatian: Nuspojave u kliničkim ispitivanjima i iz spontanih prijava bolesnika koje su se javljale kod >1%, bolesnika, navedene su u donjoj tablici prema klasifikaciji organskih sustava i učestalosti (vrlo često: ≥ 1/10, često: ≥ 1/100 < 1/10, manje često: ≥ 1/1.000 i < 1/100, rijetko: ≥ 1/10.000 i < 1/1.000, vrlo rijetko: < 1/10.000).
English: Miglustat has been used in clinical trials at doses ten times higher than the recommended dose: this caused decreases in white blood cells and other side effects similar to those described in section 4.
Croatian: Miglustat je korišten u kliničkim ispitivanjima u deset puta većim dozama od preporučenih: to je uzrokovalo smanjenje broja bijelih krvnih stanica i druge nuspojave slične onima opisanim u dijelu 4.
English: Do not give this medicine to children and adolescents (below 18 years old) with type 1 Gaucher disease because it is not known if it works in this disease.
Croatian: Ovaj lijek nemojte davati djeci ni adolescentima (mlađim od 18 godina) s Gaucherovom bolesti tipa 1 jer nije poznato djeluje li kod njih.
English: Over the range of data available, no significant relationships or trends were noted between miglustat pharmacokinetic parameters and demographic variables (age, BMI, gender or race).
Croatian: U rasponu dostupnih podataka, nisu primijećeni značajni odnosi ili trendovi između farmakokinetičkih parametara miglustata i demografskih varijabli (dob, indeks tjelesne mase, spol ili rasa).
English: Miglustat did not show any potential for mutagenic or clastogenic effects in the standard battery of genotoxicity tests.
Croatian: Miglustat nije pokazao nikakav potencijal za mutagene ili klastogene učinke u standardnom nizu testova genotoksičnosti.
English: Concomitant administration of food decreases the rate of absorption (Cmax was decreased by 36% and tmax delayed 2 hours), but has no statistically significant effect on the extent of absorption of miglustat (AUC decreased by 14%).
Croatian: Istovremeno uzimanje hrane smanjuje brzinu apsorpcije (Cmax je smanjen za 36% a tmax je 2 sata dulji), ali nema statistički značajnog utjecaja na apsorpciju miglustata (AUC snižena za 14%).
English: Following administration of a single dose of 100 mg 14C-miglustat to healthy volunteers, 83% of the radioactivity was recovered in urine and 12% in faeces.
Croatian: Nakon davanja jedne doze od 100 mg 14C-miglustata zdravim dobrovoljcima, 83% radioaktivno označenog lijeka izlučeno je u urinu a 12% u fecesu.
English: In some cases the doctor may prescribe anti-diarrhoeal medicines such as loperamide.
Croatian: U nekim slučajevima liječnik može propisati lijek protiv proljeva kao što je loperamid.
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Croatian: Preosjetljivost na djelatnu tvar ili bilo koju od pomoćnih tvari navedenih u dijelu 6.1.
English: Gastrointestinal disturbances
Croatian: Gastrointestinalni poremećaji
English: Rouboslaan 32 (ground floor) 2252 TR, Voorschoten
Croatian: Rouboslaan 32 (ground floor) 2252 TR, Voorschoten Nizozemska
English: In the first 6 months in patients who were switched to miglustat, liver and spleen organ volumes and haemoglobin levels were unchanged.
Croatian: U prvih 6 mjeseci kod bolesnika koji su prešli na miglustat, volumeni jetre i slezene i razine hemoglobina bili su nepromijenjeni.
English: Among the 41 patients enrolled in the trial 14 patients were treated with Yargesa for more than 3 years.
Croatian: Od 41 bolesnika uključenih u ispitivanje 14 bolesnika je liječeno Yargesa duže od 3 godine.
English: Dosing in patients under the age of 12 years should be adjusted on the basis of body surface area as illustrated below:
Croatian: Doziranje u bolesnika mlađih od 12 treba prilagoditi ovisno o veličini površine tijela kako je niže prikazano:
English: This means a daily maximum of six capsules (600 mg).
Croatian: To znači da je dnevni maksimum šest kapsula (600 mg).
English: Repeated-dose toxicity studies in rats showed effects on the seminiferous epithelium of the testes.
Croatian: Ispitivanja toksičnosti ponovljenih doza na štakorima pokazala su učinke na seminiferni epitel testisa.
English: An additional monotherapy study was performed in 18 patients at a total daily dose of 150 mg, and results indicate reduced efficacy compared to a total daily dose of 300 mg.
Croatian: Dodatno ispitivanje monoterapije provedeno je na 18 bolesnika s ukupnom dnevnom dozom od 150 mg, a rezultati ukazuju na smanjenu djelotvornost u usporedbi s ukupnom dnevnom dozom od 300 mg.
English: When compared to the measurements at 6 months, disease control was unchanged after 18 and 24 months of miglustat monotherapy (20 and 6 patients, respectively).
Croatian: U usporedbi s mjerenjima provedenim nakon 6 mjeseci, kontrola bolesti bila je nepromijenjena nakon 18 i 24 mjeseca monoterapije miglustatom (20 odnosno 6 bolesnika).
English: PHARMACEUTICAL FORM AND CONTENTS 84 x 1 hard capsules
Croatian: OBLIK I SADRŽAJ 84 x 1 tvrda kapsula
English: Data in severe renal impairment are limited to two patients with creatinine clearance in the range 18 - 29 ml/min and cannot be extrapolated below this range.
Croatian: Podatci kod teškog poremećaja funkcije bubrega ograničeni su na dva bolesnika s klirensom kreatinina u rasponu od 18 - 29 ml/min i ne mogu se ekstrapolirati ispod tog raspona.
English: The most abundant metabolite in urine was miglustat glucuronide accounting for 5% of the dose.
Croatian: Najprisutniji metabolit u urinu bio je miglustat glukuronid koji je činio 5% doze.
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS BLISTER
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI BLISTER BLISTER
English: This study also indicated that miglustat has no or limited effect on the pharmacokinetics of imiglucerase.
Croatian: To ispitivanje ukazuje također na to da miglustat nema nikakvo ili ima ograničeno djelovanje na farmakokinetiku imigluceraze.
English: These data suggest a decrease in CL/F by at least 70% in patients with severe renal impairment.
Croatian: Ti podatci ukazuju na smanjenje CL/F za najmanje 70% u bolesnika s teškim poremećajem funkcije bubrega.
English: Depression, insomnia, libido decreased Nervous system disorders Very common
Croatian: Depresija, nesanica, smanjen libido Poremećaji živčanog sustava Vrlo često
English: BATCH NUMBER<, DONATION AND PRODUCT CODES> Lot
Croatian: 13. BROJ SERIJE<, OZNAKE DONACIJE I PROIZVODA> Serija
English: Your doctor will perform some tests before and during treatment with Yargesa to assess this (see section 2).
Croatian: Liječnik će provesti neke pretrage prije i za vrijeme liječenja lijekom Yargesa kako bi to procijenio (vidjeti dio 2).
English: In type 1 Gaucher disease, these tremors were described as an exaggerated physiological tremor of the hands.
Croatian: Kod Gaucherove bolesti tipa 1, ti su tremori opisani kao pretjerani fiziološki tremor ruku.
English: Changes in lactation were observed in female rats in a 1-year study.
Croatian: Tijekom 1-godišnjeg ispitivanja uočene su promjene u laktaciji kod ženskih štakora.
English: If you do get any of these effects, please seek medical advice from your doctor as soon as possible.
Croatian: Ako imate bilo koju od tih nuspojava, zatražite savjet svog liječnika što je prije moguće.
English: In addition 12 paediatric patients were enrolled in an uncontrolled substudy for an overall average duration of 3.1 years and up to 4.4 years.
Croatian: Osim toga 12 pedijatrijskih bolesnika bilo je uključeno u nekontrolirano podispitivanje u ukupnom prosječnom trajanju od 3,1 godine pa do 4,4 godine.
English: Other medicines and Yargesa Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: Both data sets included paediatric, adolescent and adult patients with an age range of 1 year to 43 years.
Croatian: Oba seta podataka uključuju pedijatrijske, adolescentne i odrasle bolesnike dobnog raspona od 1 do 43 godine.
English: Driving and using machines Yargesa may make you feel dizzy.
Croatian: Upravljanje vozilima i strojevima Yargesa može uzrokovati omaglicu.
English: Data to support safety and efficacy of Yargesa in Niemann-Pick type C disease come from a prospective open-label clinical trial and a retrospective survey.
Croatian: Podatci koji podupiru sigurnost i djelotvornost Yargesa u Niemann-Pickovoj bolesti tipa C potječu iz prospektivnog otvorenog kliničkog ispitivanja i retrospektivne analize.
English: Niemann-Pick type C disease is a very rare, invariably progressive and eventually fatal neurodegenerative disorder characterised by impaired intracellular lipid trafficking.
Croatian: Niemann-Pickova bolest tipa C je vrlo rijedak, uvijek progresivan i u konačnici smrtonosan neurodegenerativni poremećaj koji karakterizira poremećen intracelularni transport lipida.
English: The main effects common to all species were weight loss and diarrhoea, and, at higher doses, damage to the gastrointestinal mucosa (erosions and ulceration).
Croatian: Glavni učinci zajednički svim vrsta bili su gubitak tjelesne težine i proljev, a pri višim dozama, oštećenje gastrointestinalne sluznice (erozije i ulceracije).
English: Of these patients, 132 had type 1 Gaucher disease, and 40 had Niemann-Pick type C disease.
Croatian: Od tih bolesnika, 132 su imala Gaucherovu bolest tipa 1, a 40 je imalo Niemann-Pickovu bolest tipa
English: If you have Niemann-Pick type C disease, fats such as glycosphingolipids build up in the cells of your brain.
Croatian: Ako imate Niemann-Pickovu bolest tipa C, masti kao što su glikosfingolipidi nakupljaju se u stanicama Vašeg mozga.
English: Limited data suggest that co-administration of miglustat and enzyme replacement with imiglucerase in patients with type 1 Gaucher disease may result in decreased exposure to miglustat (approximate reductions of 22% in Cmax and 14% in AUC were observed in a small parallel-group study).
Croatian: Ograničeni podaci ukazuju na to da istodobna primjena miglustata i enzimskog nadomjestka s imiglucerazom u bolesnika s Gaucherovom bolesti tipa 1 može za posljedicu imati smanjenu izloženost miglustatu (približno smanjenje od 22% u Cmax i 14% u AUC zabilježeno u malom ispitivanju s paralelnim skupinama).
English: For children less than 12 years old, your doctor will adjust the dose for Niemann-Pick type C disease.
Croatian: Kod djece mlađe od 12 godina, liječnik će prilagoditi dozu za Niemann-Pickovu bolest tipa C.
English: Contraceptive measures should be used by women of childbearing potential.
Croatian: Metode kontracepcije trebaju koristiti i žene reproduktivne dobi.
English: An open-label, non-comparative, 2-year study enrolled 42 patients with type 1 Gaucher disease, who had received a minimum of 3 years of ERT and who fulfilled criteria of stable disease for at least 2 years.
Croatian: Nekomparativno, 2-godišnje otvoreno ispitivanje uključivalo je 42 bolesnika s Gaucherovom bolesti tipa 1, koji su najmanje 3 godine primali ERT, a koji su zadovoljavali kriterij stabilne bolesti od najmanje 2 godine.
English: After 3 years of continuous miglustat treatment, mean reductions in liver and spleen organ volume were 17.5% and 29.6%, respectively.
Croatian: Nakon 3 godine neprekidnog liječenja miglustatom, prosječno smanjenje volumena jetre i slezene bilo je 17,5% odnosno 29,6%.
English: There was no drug-related increase in tumour incidence in male or female rats in any other organ.
Croatian: Nije bilo povećanja incidencije tumora povezanih s lijekom u muških ili ženskih štakora ni u kojem drugom organu.
English: The metabolite accounting for this has not been identified, but may accumulate and reach concentrations exceeding those of miglustat at steady state.
Croatian: Metabolit koji je za to odgovoran nije utvrđen, ali se može akumulirati i dosegnuti koncentracije koje nadilaze one miglustata pri stanju dinamičke ravnoteže.
English: This means a daily maximum of three capsules (300 mg).
Croatian: To znači da je dnevni maksimum tri kapsule (300 mg).
English: Yargesa is a white hard capsule that consists of an opaque white cap and body with “708” printed in black on the body.
Croatian: Yargesa je bijela tvrda kapsula s neprozirnom bijelom kapicom i tijelom na kojem je crnom bojom otisnuto „708“.