FrancophonIA/ELRC3.0 huggingface dataset:
English: Therefore, the interaction profile of the compounds must be considered as a combination.
Croatian: Stoga se interakcijski profil supstanci mora promatrati kao kombinacija.
English: No adverse effects on behaviour, reproduction or development of offspring were reported.
Croatian: Nisu prijavljeni štetni učinci na ponašanje, reprodukciju ili razvoj mladunčadi.
English: 24 weeks n/N % CIa n/N % CIa
Croatian: 24 tjedna n/N % CIa n/N % CIa
English: Frequency not known: cannot be estimated based on available data
Croatian: Nepoznata učestalost: ne može se procijeniti iz dostupnih podataka
English: • Worsening liver problems.
Croatian: • Pogoršanje jetrenih tegoba.
English: What Exviera is and what it is used for
Croatian: Što je Exviera i za što se koristi
English: to thin the blood
Croatian: za razrjeđivanje krvi
English: b. N=66 for the NS5B target.
Croatian: b. N=66 za ciljno mjesto NS5B.
English: Activity in cell culture and biochemical studies
Croatian: Aktivnost u staničnoj kulturi i biokemijskim ispitivanjima
English: • Do not chew, crush or break the tablets as they may have a bitter taste.
Croatian: • Nemojte žvakati, drobiti ni lomiti tablete jer tada mogu imati gorak okus.
English: Patients should be instructed not to take a double dose.
Croatian: Bolesnike je potrebno upozoriti da ne uzimanju dvostruku dozu.
English: Also see section 4.6.
Croatian: Vidjeti i dio 4.6.
English: Seven metabolites were identified in plasma.
Croatian: U plazmi je pronađeno sedam metabolita.
English: The recommended dose is one tablet, twice a day.
Croatian: Preporučena doza je jedna tableta dvaput na dan.
English: If you feel tired, do not drive or use any machines.
Croatian: Ako osjećate umor, nemojte upravljati vozilom niti raditi sa strojevima.
English: Other medicines and Exviera
Croatian: Drugi lijekovi i Exviera
English: The final study report shall be submitted by:
Croatian: Završno izvješće o ispitivanju treba dostaviti:
English: The combination was not linked to any particular safety issues in a limited set of patients treated for 12-24 weeks.
Croatian: Kombinacija se nije povezala ni sa kojim posebnim sigurnosnim pitanjima u ograničenoj skupini bolesnika koji su se liječili tijekom 12 do 24
English: Contents of the pack and other information What Exviera contains
Croatian: Sadržaj pakiranja i druge informacije Što Exviera sadrži
English: • Trouble sleeping (insomnia)
Croatian: • tegobe sa spavanjem (nesanica)
English: Reduce pravastatin dose by 50%.
Croatian: NP Smanjiti dozu pravastatina za 50%.
English: Two subjects received a blood transfusion.
Croatian: Dva su ispitanika primila transfuziju krvi.
English: Hepatitis B virus reactivation
Croatian: Reaktivacija virusa hepatitisa B
English: Date of first authorisation: 15 January 2015 Date of latest renewal:
Croatian: Datum prvog odobrenja: 15. siječnja 2015.
English: ANTIBIOTICS (SYSTEMIC ADMINISTRATION)
Croatian: ANTIBIOTICI (SISTEMSKA PRIMJENA)
English: Pregnancy and contraception
Croatian: Trudnoća i kontracepcija
English: Persistence of resistance-associated substitutions
Croatian: Postojanost supstitucija povezanih s rezistencijom
English: Exviera tablets do not work on their own.
Croatian: Exviera tablete ne djeluju ako se uzimaju samostalno.
English: Do not stop taking Exviera unless your doctor tells you to.
Croatian: Nemojte prestati uzimati lijek Exviera, osim ako Vam to ne kaže liječnik.
English: 67061 Ludwigshafen Germany
Croatian: 67061 Ludwigshafen
English: Patients should be instructed to swallow the tablets whole (i.e. patients should not chew, break or dissolve the tablet).
Croatian: Bolesnike je potrebno uputiti da tablete progutaju cijele (tj. bolesnici ne smiju žvakati, lomiti niti otapati tabletu).
English: • If you are allergic to dasabuvir or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na dasabuvir ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.)
English: What Exviera looks like and contents of the pack
Croatian: Kako Exviera izgleda i sadržaj pakiranja
English: 14 film-coated tablets Component of a multipack, can't be sold separately.
Croatian: 14 filmom obloženih tableta Sastavni dio višestrukog pakiranja, ne može se prodavati odvojeno.
English: Race or ethnicity
Croatian: Rasa ili etničko podrijetlo
English: Main characteristics are shown below.
Croatian: Glavne karakteristike su prikazane u nastavku.
English: • Take the tablets with food.
Croatian: • Tablete uzimajte s hranom.
English: • Swallow the tablets whole with water.
Croatian: • Tablete progutajte cijele s vodom.
English: Changes in selected laboratory parameters are described in Table 4.
Croatian: Promjene odabranih laboratorijskih parametara opisane su u Tablici
English: Efficacy analyses performed on other parts of the study demonstrated similarly high SVR12 rates.
Croatian: Analize podataka o djelotvornosti za ostale dijelove ispitivanja pokazale su slično visoke stope odgovora SVR12.
English: If you accidentally take more than the recommended dose, you should contact your doctor or go to the nearest hospital straight away.
Croatian: Ako slučajno uzmete veću dozu od preporučene, odmah se javite svom liječniku ili otiđite u najbližu bolnicu.
English: This medicine is available without a prescription
Croatian: Ovaj se lijek može nabaviti bez recepta.
English: It is important not to miss a dose of this medicine.
Croatian: Važno je da ne propustite uzeti dozu ovoga lijeka.
English: Ribavirin may cause severe birth defects.
Croatian: Ribavirin može uzrokovati teške urođene mane djeteta.
English: a herbal medicine for anxiety and mild depression.
Croatian: biljni lijek za liječenje tjeskobe i blage depresije.
English: Frequencies are defined as follows: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000) or very rare (<1/10,000).
Croatian: Učestalost je definirana kao: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000
English: The recommended tacrolimus dosing is 0.5 mg every 7 days.
Croatian: Preporučena doza takrolimusa je 0,5 mg svakih 7 dana.
English: If you take more Exviera than you should
Croatian: Ako uzmete više lijeka Exviera nego što ste trebali
English: Missed doses
Croatian: Propuštene doze
English: No subject received a blood transfusion.
Croatian: Nijedan ispitanik nije primio transfuziju krvi.
English: • Swelling of the layers of skin which can affect any part of the body including the face, tongue or throat and may cause difficulty swallowing or breathing (angioedema)
Croatian: • oticanje slojeva kože koje može zahvatiti bilo koji dio tijela, uključujući lice, jezik ili grlo što može uzrokovati poteškoće u gutanju ili disanju (angioedem).
English: There are some medicines you must not take with Exviera - see the previous table “Medicines you must not take with Exviera”.
Croatian: Postoje određeni lijekovi koje ne smijete uzimati s lijekom Exviera - pogledajte prethodnu tablicu „Lijekovi koje ne smijete uzimati s lijekom Exviera“.
English: 60 patients were randomized and treated, and 60/60 (100%) achieved SVR12.
Croatian: 60 je bolesnika bilo randomizirano i liječeno te je 60/60 (100%) postiglo SVR12.
English: Raltegravir exposure is substantially increased (2-fold).
Croatian: Izloženost raltegraviru je značajno povećana (2 puta).
English: SVR12 rates for recommended treatment regimens by patient population
Croatian: Stope SVR12 za preporučene režime liječenja prema populaciji bolesnika
English: • If you are taking any of the medicines listed in the following table.
Croatian: • ako uzimate neki od lijekova navedenih u tablici u nastavku.
English: 24 weeks
Croatian: 24 tjedana
English: *Your doctor may need to increase the frequency of your blood tests to check how well your blood can clot.
Croatian: *Vaš liječnik će možda morati povećati učestalost vaših krvnih pretraga kako bi provjerio zgrušavanje
English: • If you or your partner becomes pregnant during treatment with Exviera and ribavirin or in the months that follow, you must contact your doctor immediately.
Croatian: • Ako Vi ili Vaša partnerica zatrudnite tijekom liječenja lijekom Exviera i ribavirinom ili u nekoliko narednih mjeseci nakon prestanka liječenja, odmah se obratite Vašem liječniku.
English: Early discontinuation may result in drug resistance, but implications for future therapy are not known.
Croatian: Prijevremeni prekid liječenja može razviti rezistenciju na lijek, ali utjecaj na buduću terapiju nije poznat.
English: Paediatric population Drug interaction studies have only been performed in adults.
Croatian: Pedijatrijska populacija Ispitivanja interakcija provedena su samo u odraslih.
English: SEDATIVES / HYPNOTICS Zolpidem
Croatian: SEDATIVI / HIPNOTICI Zolpidem
English: Expected:
Croatian: Očekuje se:
English: 25 mg once daily administered in the morning, with food
Croatian: 25 mg jedanput na dan primjenjen ujutro s hranom
English: Sirolimus blood concentrations should be monitored every 4 to 7 days until 3 consecutive trough levels have shown stable concentrations of sirolimus.
Croatian: Potrebno je pratiti koncentracije sirolimusa u krvi svakih 4 do 7 dana dok 3 uzastopne najniže koncentracije ne pokažu stabilne razine sirolimusa.
English: Table 16 shows SVR rates for these subjects.
Croatian: U Tablici 16 prikazane su stope SVR-a za te ispitanike.
English: 95% CIa F0-F1
Croatian: SVR12 95% CIa F0-F1
English: NA Decrease in amlodipine dose by 50% and monitor patients for clinical effects.
Croatian: NP Smanjenje doze amlodipina za 50% i nadzor kliničkih učinaka kod bolesnika.
English: - have diabetes.
Croatian: - imate šećernu bolest.
English: Main demographics in TURQUOISE-III Characteristics
Croatian: Glavne demografske karakteristike ispitanika u TURQUOISE-III
English: Pharmacotherapeutic group: Antivirals for systemic use; direct-acting antivirals, ATC code: J05AP09
Croatian: Farmakoterapijska skupina: Antivirotici za sistemsku uporabu; direktno djelujući antivirotici, ATK oznaka: J05AP09
English: • Feeling weak or lack of energy (asthenia).
Croatian: • slabost ili nedostatak energije (astenija)
English: Design:
Croatian: Dizajn:
English: The interactions with pitavastatin and fluvastatin have not been investigated.
Croatian: Interakcije s pitavastatinom i fluvastatinom nisu ispitane.
English: HBV screening should be performed in all patients before initiation of treatment.
Croatian: Probir na HBV mora se provesti u svih bolesnika prije početka liječenja.
English: Mechanism:
Croatian: Mehanizam:
English: • Decide what other medicines you should take with Exviera and for how long.
Croatian: • utvrdio koje lijekove morate uzimati s lijekom Exviera i koliko dugo
English: 12 weeks
Croatian: 12 tjedana
English: Do not give Exviera to children and adolescents under 18 years of age.
Croatian: Exviera se ne smije davati djeci i adolescentima mlađima od 18 godina.
English: If the combination is used, repeated ECGmonitoring should be done, see section 4.4.
Croatian: Ako se primjenjuje kombinacija, mora se ponavljano provoditi EKG praćenje, vidjeti dio 4.4.
English: Pitavastatin and fluvastatin
Croatian: Pitavastatin i fluvastatin
English: Norgestimate metabolites:
Croatian: Metaboliti norgestimata:
English: Q80K, although a highly prevalent polymorphism in NS3 (41.2% of samples), confers minimal resistance to paritaprevir.
Croatian: Q80K, iako uvjerljivo najzastupljeniji polimorfizam proteina NS3 (41,2% uzoraka), uzrokuje minimalnu rezistenciju na paritaprevir.
English: In order to evaluate the recurrence of hepatocellular carcinoma associated with dasabuvir, the MAH shall conduct and submit the results of a prospective safety study using data deriving from a cohort of a well-defined group of patients, based on an agreed protocol.
Croatian: Kako bi se procijenilo ponovno pojavljivanje hepatocelularnog karcinoma povezanog s primjenom dasabuvira, nositelj odobrenja mora provesti i dostaviti rezultate prospektivnog ispitivanja sigurnosti, koristeći podatake koji proizlaze iz kohorte dobro definirane skupine bolesnika, na temelju dogovorenog protokola.
English: Ribavirin stays for a long time in the body after treatment is stopped, and effective contraception is therefore needed both during treatment and for some time afterwards.
Croatian: Ribavirin ostaje u tijelu dugo nakon prekida liječenja te je stoga potrebna učinkovita kontracepcija tijekom liječenja te neko vrijeme nakon prestanka liječenja.
English: You or your caregiver should also immediately inform your doctor of any changes in behaviour or mood and of any suicidal thoughts you may have.
Croatian: Vi ili Vaš njegovatelj također trebate odmah obavijestiti liječnika o bilo kakvim promjenama u ponašanju ili raspoloženju i bilo kakvim mislima o samoubojstvu.
English: AbbVie (as logo)
Croatian: AbbVie (kao logo)
English: Part 1 of the study was a Phase 2 pilot cohort consisting of 2 parts, Part 1a (63 subjects) and Part 1b (22 subjects).
Croatian: Prvi dio ispitivanja bilo je kohortno pilot ispitivanje faze 2 koje se sastojalo od 2 dijela, dijela 1a (63 ispitanika) i dijela 1b (22 ispitanika).
English: Tell your doctor if you have a history of depression or psychiatric illness.
Croatian: Obavijestite svog liječnika ako ste nekad imali depresiju ili psihijatrijsku bolest.
English: A 10 kg change in body weight from 76 kg (median weight in the Phase 3 studies) would result in <10% change in dasabuvir exposures.
Croatian: Promjena od 10 kg pri tjelesnoj težini od 76 kg (medijan težine u fazi 3 ispitivanja) rezultira u <10% promjene u izloženosti dasabuviru.
English: C12:= concentration at 12 hours following single dose of everolimus.
Croatian: C12:= koncentracija 12 sati nakon primjene jedne doze everolimusa.
English: Some diabetic patients have experienced low sugar levels in the blood (hypoglycaemia) after starting treatment with medicines like Exviera.
Croatian: U nekih bolesnika sa šećernom bolesti zabilježene su niske razine šećera u krvi (hipoglikemija) nakon početka liječenja lijekovima kao što je Exviera.
English: See additional information on specific hormonal contraceptives in sections 4.3 and 4.4.
Croatian: Vidjeti dodatne informacije o određenim hormonskim kontraceptivima u dijelovima 4.3 i 4.4.
English: • efavirenz, nevirapine, etravirine
Croatian: • efavirenz, nevirapin, etravirin
English: See the section on contraception below.
Croatian: Vidjeti dio o kontraceptivima u nastavku.
English: The recommended dose is 250 mg of dasabuvir (one tablet) twice daily (morning and evening).
Croatian: Preporučena doza je 250 mg dasabuvira (jedna tableta) dvaput na dan (ujutro i navečer).
English: Depression, including suicidal thoughts and behaviours, has been reported in some patients taking this medicine, particularly in patients with a prior history of depression or psychiatric illness or in patients taking ribavirin with this medicine.
Croatian: Depresija, uključujući misli o samoubojstvu i suicidalno ponašanje, prijavljena je u nekih bolesnika koji su uzimali ovaj lijek, posebice u bolesnika koji su ranije imali depresiju ili psihijatrijsku bolest ili u bolesnika koji uz ovaj lijek uzimaju i ribavirin.
English: Such medicinal products include sulfasalazine, imatinib and some of the statins (see Table 2).
Croatian: Ti lijekovi uključuju sulfasalazin, imatinib i neke statine (vidjeti Tablicu 2).
English: The lack of detection of virus containing a resistance-associated substitution does not indicate that the resistant virus is no longer present at clinically significant levels.
Croatian: To što virus sa supstitucijom povezanom s rezistencijom više nije mjerljiv ne znači da rezistentan virus više nije prisutan u klinički značajnim količinama.
English: Your doctor will talk with you about which of these medicines to take with Exviera.
Croatian: Liječnik će Vam reći koje od tih lijekova trebate uzimati s lijekom Exviera.
English: The effects of Exviera during pregnancy are not known.
Croatian: Učinci lijeka Exviera u trudnoći nisu poznati.
English: Unchanged dasabuvir accounted for 26.2% and M1 for 31.5% of the total dose in faeces.
Croatian: Nepromijenjeni dasabuvir iznosio je 26,2%, a M1 31,5% ukupne doze u fecesu.
English: Most patients with these severe outcomes had evidence of advanced or decompensated cirrhosis prior to initiating therapy.
Croatian: Kod većine bolesnika s tim teškim ishodima postojali su znakovi uznapredovale ili dekompenzirane ciroze prije početka terapije.
English: Elimination half-life in rat milk was slightly shorter than in plasma, AUC was about 2 fold of that in plasma.
Croatian: Poluvrijeme eliminacije u mlijeku štakora bilo je nešto kraće nego u plazmi, dok je AUC bio dvostruko veći nego u plazmi.
English: No (for any parameter listed above) *AFP= serum alpha fetoprotein
Croatian: Ne (za neki od navedenih parametara) *AFP= α-fetoprotein u serumu
English: Stop taking Exviera and talk to your doctor or get medical help immediately if any of the following occur:
Croatian: Prekinite uzimanje lijeka Exviera i obratite se svom liječniku ili odmah potražite medicinsku pomoć ako se bilo što od navedenog pojavi:
English: NA Monitor patients for clinical effects; a decrease in furosemide dose of up to 50% may be required.
Croatian: NP Nadzor kliničkih učinaka kod bolesnika; može biti potrebno smanjenje doze furosemida do 50%.
English: Number of Responders at the End of Treatment
Croatian: Broj ispitanika s odgovorom na liječenje na završetku ispitivanja
English: Dasabuvir has no or negligible influence on the ability to drive and use machines.
Croatian: Dasabuvir ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: GARNET (open-label)
Croatian: GARNET (otvoreno)
English: Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Croatian: Bolesnici s rijetkim nasljednim poremećajem nepodnošenja galaktoze, potpunim nedostatkom laktaze ili malapsorpcijom glukoze i galaktoze ne bi smjeli uzimati ovaj lijek.
English: While no change in the pharmacokinetics of warfarin is expected, close monitoring of INR is recommended with all vitamin K antagonists.
Croatian: Iako nije očekivana promjena farmakokinetike varfarina, preporučuje se pomni nadzor INR-a kod primjene svih antagonista vitamina K.
English: NA Clinical monitoring of patients is recommended.
Croatian: NP Preporučuje se klinički nadzor bolesnika.
English: Limited data in patients with end-stage renal disease indicate no clinically significant changes in exposure also in this patient group.
Croatian: Ograničeni podaci u bolesnika sa završnim stadijem bubrežne bolesti ukazuju na nepostojanje klinički značajnih promjena u izloženosti niti u ovoj skupini bolesnika.
English: Women of childbearing potential /contraception in males and females
Croatian: Žene reproduktivne dobi / kontracepcija u muškaraca i žena
English: In cell culture
Croatian: U staničnoj kulturi
English: The use of Exviera in children and adolescents has not yet been studied.
Croatian: Primjena lijeka Exviera u djece i adolescenata još nije ispitana.
English: The safety and efficacy of dasabuvir in children less than 18 years of age have not been established.
Croatian: Sigurnost i djelotvornost dasabuvira u djece mlađe od 18 godina nisu ustanovljene.
English: In Phase 3 clinical trials, 1075 subjects (including 181 with compensated cirrhosis) received the recommended regimen (see section 4.2).
Croatian: U kliničkim ispitivanjima faze 3, 1075 ispitanika (uključujući 181 ispitanika s kompenziranom cirozom) primalo je preporučeni režim liječenja (vidjeti dio 4.2).
English: Potential for other medicinal products to affect the pharmacokinetics of dasabuvir
Croatian: Mogući utjecaj drugih lijekova na farmakokinetiku dasabuvira
English: As a precautionary measure, it is preferable to avoid the use of dasabuvir during pregnancy.
Croatian: Kao mjeru opreza poželjno je izbjegavati primjenu dasabuvira u trudnoći.
English: If more than 6 hours have passed since dasabuvir is usually taken, the missed dose should NOT be taken and the patient should take the next dose per the usual dosing schedule.
Croatian: Ako je prošlo više od 6 sati od uobičajenog vremena uzimanja doze dasabuvira, propuštena doza se NE smije uzeti nego bolesnik mora nastaviti sa sljedećom dozom prema uobičajenom rasporedu doziranja.
English: • apalutamide, enzalutamide
Croatian: • apalutamid, enzalutamid
English: SAPPHIRE I and II PEARL II, III, and IV TURQUOISE II (subjects with cirrhosis)
Croatian: PEARL II, III i IV TURQUOISE II (ispitanici s cirozom)
English: In case of overdose, it is recommended that the patient be monitored for any signs or symptoms of adverse reactions or effects and appropriate symptomatic treatment instituted immediately.
Croatian: U slučaju predoziranja, preporučuje se nadzirati bolesnika zbog mogućih znakova ili simptoma nuspojava ili štetnih učinaka te odmah uvesti odgovarajuće simptomatsko liječenje.
English: Dasabuvir is highly bound to plasma proteins.
Croatian: Dasabuvir se u velikoj mjeri veže za proteine u plazmi.
English: Four subjects experienced a haemoglobin level < 8 g/dL.
Croatian: U četiri ispitanika razina hemoglobina iznosila je < 8 g/dl.
English: For immunosuppressive medication, most subjects were taking tacrolimus (81%), with the remainder taking cyclosporine.
Croatian: Od imunosupresiva većina je bolesnika uzimala takrolimus (81%), a ostali ciklosporin.
English: Also contains lactose.
Croatian: Sadrži i laktozu.
English: Do not take Exviera if any of the above apply to you.
Croatian: Nemojte uzeti lijek Exviera ako se nešto od navedenoga odnosi na Vas.
English: All clinical trials with dasabuvir have been conducted following administration with food.
Croatian: Sva klinička ispitivanja dasabuvira provedena su nakon njegove primjene s hranom.
English: Rilpivirine should be used cautiously, in the setting of repeated ECG monitoring.
Croatian: Rilpivirin se mora primjenivati s oprezom, uz redovito praćenje EKG-a.
English: Take one tablet in the morning.
Croatian: Uzmite jednu tabletu ujutro.
English: Take one tablet in the morning and one tablet in the evening.
Croatian: Uzmite jednu tabletu ujutro i jednu tabletu navečer.
English: G558R and D559G/N were observed as treatment-emergent substitutions but the activity of dasabuvir against these variants could not be evaluated due to poor replication capacity.
Croatian: D559G/N primijećene su kao supstitucije nastale tijekom liječenja, ali aktivnost dasabuvira protiv tih varijanti nije se moglo ocijeniti zbog slabe sposobnosti replikacije.
English: C24:= concentration at 24 hours following single dose of cyclosporine, tacrolimus or sirolimus.
Croatian: C24:= koncentracija 24 sata nakon primjene jedne doze ciklosporina, takrolimusa ili sirolimusa.
English: When coadministered they exert mutual effects on each other (see section 5.2).
Croatian: Istodobnom primjenom imaju međusobni učinak jedan na drugoga (vidjeti dio 5.2).
English: This regimen can be used in the absence of extensive PI resistance (i.e. lack of darunavir associated RAMs), see also section 4.4.
Croatian: Ovaj režim može se primjenjivati u odsustvu opsežne rezistencije na PI (tj. ako nema mutacija povezanih s rezistencijom na darunavir), također vidjeti dio 4.4.
English: Dasabuvir M1 metabolite was quantified in all the drug interaction studies.
Croatian: Metabolit dasabuvira M1 kvantitativno je određivan u svim ispitivanjima interakcija između lijekova.
English: The replicon activity of dasabuvir was attenuated 12- to 13fold in the presence of 40% human plasma.
Croatian: Aktivnost dasabuvira protiv replikona bilo je 12 do 13 puta slabije u prisutnosti 40% ljudske plazme.
English: Overall, 61% had fibrosis stage F0-F1, 26% F2, 9% F3, and 4% F4.
Croatian: 4. Sveukupno je 61% ispitanika imalo fibrozu stadija F0 - F1, 26% stadija F2, 9% stadija F3, a 4% stadija F4.
English: Exviera is an antiviral medicine used to treat adults with chronic (long-term) hepatitis C (an infectious disease that affects the liver, caused by the hepatitis C virus).
Croatian: Exviera je antivirusni lijek koji se koristi za liječenje odraslih koji boluju od kroničnog (dugotrajnog) hepatitisa C (infektivna bolest koja zahvaća jetru, a uzrokuje je virus hepatitisa C).