FrancophonIA/ELRC3.0 huggingface dataset:
English: Humira was numerically favoured for the majority of subscores with statistically significant mean differences for general vision, ocular pain, near vision, mental health, and total score in Study UV I, and for general vision and mental health in Study UV II.
Croatian: Većina podrezultata brojčano je išla u prilog lijeku Humira, a srednje vrijednosti razlike bile su statistički značajne za opći vid, bol u oku, vid na blizinu, mentalno zdravlje i ukupan rezultat u ispitivanju UV I te za opći vid i mentalno zdravlje u ispitivanju
English: It is recommended that paediatric patients, if possible, be brought up to date with all immunisations in agreement with current immunisation guidelines prior to initiating Humira therapy.
Croatian: Preporučuje se da se pedijatrijske bolesnike, ako je moguće, cijepi u skladu sa svim važećim smjernicama za cijepljenje prije započinjanja liječenja lijekom Humira.
English: Do not remove the caps until just before injection.
Croatian: Kapice uklonite tek neposredno prije primjene.
English: • certain disease-modifying anti-rheumatic agents (for example, sulfasalazine, hydroxychloroquine, leflunomide and injectable gold preparations)
Croatian: • nekim antireumaticima koji mijenjaju tijek bolesti (primjerice sulfasalazinom, hidroksiklorokinom, leflunomidom i injekcijskim pripravcima zlata)
English: Humira is indicated for the treatment of adults with severe axial spondyloarthritis without radiographic evidence of AS but with objective signs of inflammation by elevated CRP and / or MRI, who have had an inadequate response to, or are intolerant to non-steroidal anti-inflammatory drugs (NSAIDs).
Croatian: Humira je indicirana za liječenje teškog oblika aksijalnog spondiloartritisa kod odraslih bez radiološkog dokaza AS-a, ali s objektivnim znakovima upale u obliku povišenog C-reaktivnog proteina (CRP) i/ili nalaza magnetske rezonancije (MR), u kojih nije postignut zadovoljavajući odgovor na nesteroidne protuupalne lijekove (NSAIL-ove) ili koji ih ne podnose.
English: Hold the pre-filled pen with the grey cap (labelled ‘1') pointing up.
Croatian: Držite napunjenu brizgalicu tako da siva kapica (označena s '1') bude okrenuta prema gore.
English: The following list of adverse reactions is based on experience from clinical trials and on postmarketing experience and are displayed by system organ class and frequency in Table 3 below: very common ( 1/10); common ( 1/100 to < 1/10); uncommon ( 1/1,000 to < 1/100); rare ( 1/10,000 to < 1/1,000); and not known (cannot be estimated from the available data).
Croatian: Sljedeći popis nuspojava temelji se na iskustvu iz kliničkih ispitivanja i nakon stavljanja lijeka u promet, a prikazane su dolje u Tablici 3 prema organskom sustavu i učestalosti: vrlo često (≥ 1/10); često (≥1/100 i <1/10); manje često (≥1/1000 i <1/100); rijetko (≥1/10 000 i <1/1000) i nepoznato (ne može se procijeniti iz dostupnih podataka).
English: If you have rheumatoid arthritis and you do not receive methotrexate with your Humira therapy, your doctor may decide to give 40 mg adalimumab every week or 80 mg every other week.
Croatian: Ako imate reumatoidni artritis i ne dobivate metotreksat zajedno s lijekom Humira, Vaš liječnik može odlučiti davati Vam 40 mg adalimumaba svaki tjedan ili 80 mg svaki drugi tjedan.
English: • After injecting Humira, immediately throw away the used syringe in a special container as instructed by your doctor, nurse or pharmacist.
Croatian: • Nakon ubrizgavanja lijeka Humira, uporabljenu štrcaljku odmah bacite u poseban spremnik kako Vas je uputio Vaš liječnik, medicinska sestra ili ljekarnik.
English: Tell your doctor immediately if your child experiences symptoms like changes in vision, weakness in arms or legs or numbness or tingling in any part of the body.
Croatian: Odmah recite svom liječniku ako se kod djeteta pojave simptomi kao što su promjene vida, slabost u rukama ili nogama ili utrnulost ili trnci u bilo kojem dijelu tijela.
English: • a bump or open sore that doesn't heal;
Croatian: • oteklinu ili otvorenu ranu koja ne cijeli,
English: • When the syringe is empty, remove the needle from skin, being careful to keep it at the same angle as when it was inserted
Croatian: • Kada se štrcaljka isprazni, izvadite iglu iz kože, pazeći pri tom da je zadržite pod istim kutom pod kojim ste je i uveli.
English: One pack contains 2 boxes, each containing 1 vial, 1 empty sterile syringe, 1 needle, 1 vial adapter and 2 alcohol pads.
Croatian: kutije od kojih svaka sadrži 1 bočicu, 1 praznu sterilnu štrcaljku, 1 iglu, 1 nastavak za bočicu i 2 jastučića natopljena alkoholom.
English: Keep this Patient Reminder Card with you.
Croatian: Karticu s podsjetnikom za bolesnika držite kod sebe.
English: The recommended Humira induction dose regimen for adult patients with moderately to severely active Crohn's disease is 80 mg at Week 0 followed by 40 mg at Week 2.
Croatian: Preporučena indukcijska doza lijeka Humira u odraslih bolesnika s umjerenom do teškom aktivnom Crohnovom bolešću je 80 mg u nultom tjednu, a zatim 40 mg u drugom tjednu.
English: Table 14 Efficacy Response in Placebo-Controlled Study nr-axSpA I
Croatian: Tablica 14 Djelotvornost u placebom kontroliranom ispitivanju nr-axSpA I
English: The safety profile for patients with HS treated with Humira weekly was consistent with the known safety profile of Humira.
Croatian: Sigurnosni profil lijeka Humira u bolesnika s gnojnim hidradenitisom liječenih jednom tjedno bio je u skladu s poznatim sigurnosnim profilom lijeka Humira.
English: Humira is used to treat hidradenitis suppurativa in adults and adolescents from 12 years of age.
Croatian: Humira se koristi za liječenje gnojnog hidradenitisa u odraslih i adolescenata u dobi od 12 godina i starijih.
English: The primary endpoint in RA
Croatian: Dodatna primarna mjera ishoda ispitivanja RA
English: STEP 9
Croatian: KORAK 9
English: Results from the Short Form Health Survey (SF 36) for all doses/schedules of Humira in all four studies support these findings, with statistically significant physical component summary (PCS) scores, as well as statistically significant pain and vitality domain scores for the 40 mg every other week dose.
Croatian: Short Form Health Survey, SF 36) podupiru te nalaze za sve doze/režime davanja lijeka Humira u sva četiri ispitivanja, sa statistički značajnim rezultatom za cjelokupnu fizičku komponentu (engl.
English: Psoriatic arthritis is an inflammation of the joints associated with psoriasis.
Croatian: Psorijatični artritis je upala zglobova povezana sa psorijazom.
English: b at Weeks 24 and 36 After
Croatian: 24. tjedan 36. tjedan a
English: • nerve disorders (such as eye nerve inflammation and Guillain-Barré syndrome that may cause muscle weakness, abnormal sensations, tingling in the arms and upper body)
Croatian: • poremećaji živaca (kao upala očnog živca i Guillain-Barréov sindrom koji može uzrokovati slabost mišića, abnormalne osjete, trnce u rukama i gornjem dijelu tijela)
English: The patients received 24 mg/m2 body surface area (BSA) of Humira up to a maximum of 20 mg every other week as a single dose via SC injection for at least 24 weeks.
Croatian: Bolesnici su primali 24 mg/m2 tjelesne površine lijeka Humira, do maksimalne doze od 20 mg, svaki drugi tjedan kao pojedinačnu dozu s.c. injekcijom kroz najmanje 24 tjedna.
English: • severe rash, hives or other signs of allergic reaction;
Croatian: • težak osip, koprivnjaču ili druge znakove alergijske reakcije,
English: If you have rheumatoid arthritis and you do not receive methotrexate with your Humira therapy, your doctor may decide to give Humira 40 mg every week or 80 mg every other week.
Croatian: Ako imate reumatoidni artritis i ne dobivate metotreksat zajedno s lijekom Humira, Vaš liječnik može odlučiti davati 40 mg lijeka Humira svaki tjedan ili 80 mg svaki drugi tjedan.
English: After Week 2, patients in both adalimumab arms received 40 mg eow.
Croatian: Nakon drugog tjedna, bolesnici u obje skupine liječene adalimumabom primali su 40 mg svaki drugi tjedan.
English: After 12 weeks of therapy, patients who had received Humira in Period A were re-randomised in Period B to 1 of 3 treatment groups (Humira 40 mg every week, Humira 40 mg every other week, or placebo from Week 12 to Week 35).
Croatian: A primali lijek Humira ponovno su randomizirani u razdoblju B u jednu od 3 terapijske skupine (Humira u dozi od 40 mg svaki tjedan, Humira u dozi od 40 mg svaki drugi tjedan ili placebo od 12. do 35. tjedna).
English: The following list of adverse reactions is based on experience from clinical trials and on postmarketing experience and are displayed by system organ class and frequency in Table 6 below: very common ( 1/10); common ( 1/100 to < 1/10); uncommon ( 1/1,000 to < 1/100); rare ( 1/10,000 to < 1/1,000); and not known (cannot be estimated from the available data).
Croatian: Sljedeći popis nuspojava temelji se na iskustvu iz kliničkih ispitivanja i nakon stavljanja lijeka u promet, a prikazane su dolje u Tablici 6 prema organskom sustavu i učestalosti: vrlo često (≥ 1/10); često (≥1/100 i <1/10); manje često (≥1/1000 i <1/100); rijetko (≥1/10 000 i <1/1000) i nepoznato (ne može se procijeniti iz dostupnih podataka).
English: b 50 Week 2 Week 12 Week 24 ***,** Statistically significant at p < 0.001, < 0.01 for all comparisons between Humira and placebo at Weeks 2, 12 and 24 Assessments in Ankylosing Spondylitis Bath Ankylosing Spondylitis Disease Activity Index
Croatian: ***, **Statistički značajno uz p<0,001, p<0,01 za sve usporedbe lijeka Humira s placebom u 2., 12. i 24. tjednu a Procjena kod ankilozantnog spondilitisa (engl.
English: RA studies III and V had an additional primary endpoint at 52 weeks of retardation of disease progression (as detected by X-ray results).
Croatian: Dodatna primarna mjera ishoda ispitivanja RA III i V bilo je usporavanje progresije bolesti (na temelju radioloških nalaza) nakon 52 tjedna liječenja.
English: • inflammation of the skin (such as eczema)
Croatian: • upala kože (primjerice ekcem)
English: • 1 pre-filled pen for patient use with 2 alcohol pads (1 spare)
Croatian: • 1 napunjenu brizgalicu za uporabu od strane bolesnika i 2 jastučića natopljena alkoholom (1 rezervni)
English: Your symptoms may return upon discontinuation.
Croatian: Simptomi se mogu vratiti nakon prestanka primjene.
English: Coagulation and bleeding disorders (including activated partial thromboplastin time prolonged), autoantibody test positive (including double stranded DNA antibody), blood lactate dehydrogenase increased
Croatian: često poremećaji koagulacije i krvarenja (uključujući produljenje aktiviranog parcijalnog tromboplastinskog vremena), pozitivan nalaz testa na autoprotutijela (uključujući protutijela na dvolančanu DNK),
English: The white needle sleeve will now be exposed.
Croatian: Sada je vidljiva bijela navlaka za iglu.
English: • It is recommended that children, if possible, be given all the scheduled vaccinations for their age before they start treatment with Humira.
Croatian: • Ako je moguće, preporučuje se da djeca obave sva cijepljenja predviđena za njihovu dob prije započinjanja terapije lijekom Humira.
English: The other ingredients are mannitol, polysorbate 80 and water for injections.
Croatian: Drugi sastojci su manitol, polisorbat 80 i voda za injekcije.
English: Hypokalaemia, uric acid increased, blood sodium abnormal, hypocalcaemia, hyperglycaemia, hypophosphatemia, dehydration
Croatian: odstupanja u razinama natrija u krvi, hipokalcijemija, hiperglikemija, hipofosfatemija, dehidracija
English: • immune disorders that could affect the lungs, skin and lymph nodes (most commonly presenting as sarcoidosis)
Croatian: • imunološki poremećaji koji mogu zahvatiti pluća, kožu i limfne čvorove (najčešće se očituje kao sarkoidoza)
English: • nerve root compression (including low back pain and leg pain)
Croatian: • kompresija korijena živca (uključujući bol u donjem dijelu leđa i nozi)
English: A greater proportion of patients on Humira had no disease flare during the double-blind period, when compared with those on placebo (70.4% vs. 47.1%, p<0.001) (Figure 1).
Croatian: Razbuktavanje bolesti tijekom dvostruko slijepog razdoblja izostalo je kod većeg udjela bolesnika liječenih lijekom Humira nego onih koji su primali placebo (70,4% naspram 47,1%, p<0,001) (Slika 1).
English: Taking these results into consideration, Humira is recommended for use in combination with MTX and for use as monotherapy in patients for whom MTX use is not appropriate (see section 4.2).
Croatian: Uzimajući to u obzir, preporučuje se da se Humira daje u kombinaciji s metotreksatom, a u monoterapiji samo u onih bolesnika u kojih primjena metotreksata nije prikladna (vidjeti dio 4.2).
English: No malignancies were observed in 77 paediatric patients with an exposure of 80.0 patient years during a Humira trial in paediatric patients with chronic plaque psoriasis.
Croatian: Zloćudne bolesti nisu primijećene ni u 77 pedijatrijskih bolesnika s izloženošću od 80,0 bolesnik-godina u ispitivanju lijeka Humira provedenom u pedijatrijskih bolesnika s kroničnom plak psorijazom.
English: In patients with enthesitis-related arthritis, anti-adalimumab antibodies were identified in 10.9% (5/46) of patients treated with adalimumab.
Croatian: U bolesnika s artritisom povezanim s entezitisom, protutijela na adalimumab identificirana su u 10,9% (5/46) bolesnika liječenih adalimumabom.
English: • worsening of a condition called dermatomyositis (seen as a skin rash accompanying muscle weakness)
Croatian: • pogoršanje stanja koje se naziva dermatomiozitis (zapaženo kao kožni osip praćen s mišićnom slabošću)
English: Clinical response is decrease from baseline in Mayo score ≥ 3 points and ≥ 30% plus a decrease in the rectal bleeding subscore [RBS] ≥ 1 or an absolute RBS of 0 or 1; p < 0.05 for Humira vs. placebo pairwise comparison of proportions **p < 0.001 for Humira vs. placebo pairwise comparison of proportions a Of those receiving corticosteroids at baseline
Croatian: Klinički odgovor je smanjenje početnog Mayo rezultata za ≥ 3 boda i ≥ 30%, uz smanjenje podrezultata rektalnog krvarenja [engl. rectal bleeding subscore, RBS] za ≥1 ili apsolutni RBS od 0 ili 1; * p<0,05 za lijek Humira naspram placeba, sparena usporedba udjela ** p<0,001 za lijek Humira naspram placeba, sparena usporedba udjela a onih koji su na početku uzimali kortikosteroide
English: • As cases of tuberculosis have been reported in patients treated with Humira, your doctor will check you for signs and symptoms of tuberculosis before starting Humira.
Croatian: • Budući da su u bolesnika liječenih lijekom Humira prijavljeni slučajevi tuberkuloze, prije nego počnete s liječenjem, liječnik će provjeriti imate li znakove i simptome tuberkuloze.
English: For patients who stayed on their randomised therapy, the mean (±SD) adalimumab trough concentrations at Week 52 were 9.5 ± 5.6 g/ml for the Standard Dose group and 3.5 ± 2.2 g/ml for the Low Dose group.
Croatian: U bolesnika koji su nastavili terapiju na koju su randomizirani, srednje vrijednosti (±SD) najnižih koncentracija adalimumaba u 52. tjednu bile su 9,5 ± 5,6 µg/ml za skupinu koja je primala standardnu dozu i 3,5 ± 2,2 µg/ml za skupinu koja je primala nisku dozu.
English: Pull the Plum-coloured Cap 2 straight off.
Croatian: Ravno povucite bordo kapicu (2).
English: Humira has been studied in rheumatoid arthritis, polyarticular juvenile idiopathic arthritis and psoriatic arthritis patients taking Humira as monotherapy and those taking concomitant methotrexate.
Croatian: Djelovanje lijeka Humira ispitivano je u bolesnika s reumatoidnim artritisom, poliartikularnim juvenilnim idiopatskim artritisom i psorijatičnim artritisom koji su dobivali lijek Humira kao monoterapiju i u onih koji su istodobno uzimali i metotreksat.
English: If a few small drops of liquid come out of the needle, that is okay.
Croatian: U redu je ako iz igle izađe nekoliko manjih kapi tekućine.
English: In RA study III, where Humira treated patients had a mean duration of rheumatoid arthritis of approximately 11 years, structural joint damage was assessed radiographically and expressed as change in modified Total Sharp Score (TSS) and its components, the erosion score and joint space narrowing score.
Croatian: U ispitivanju RA III, u kojem je srednje trajanje reumatoidnog artritisa u bolesnika liječenih lijekom Humira bilo 11 godina, strukturno oštećenje zglobova procjenjivalo se radiološki, a izraženo je promjenom ukupnog zbroja bodova prema modificiranoj Sharpovoj ljestvici (engl.
English: • Do NOT shake the syringe.
Croatian: • NE tresite štrcaljku.
English: Analysis Treatment
Croatian: Analiza
English: If you have COPD, or are a heavy smoker, you should discuss with your doctor whether treatment with a TNF blocker is appropriate for you.
Croatian: Ako bolujete od KOPB-a ili ste težak pušač, provjerite kod liječnika je li liječenje TNF blokatorom primjereno za Vas.
English: Talk to your doctor or pharmacist before using Humira
Croatian: Obratite se svom liječniku ili ljekarniku prije nego primijenite lijek Humira
English: No ALT elevations ≥ 3 x ULN occurred in the Phase 3 trial of Humira in patients with polyarticular juvenile idiopathic arthritis who were 2 to <4 years.
Croatian: Nije zabilježeno povišenje razine ALT-a ≥ 3 x GGN u ispitivanju faze III u kojem se Humira primjenjivala u bolesnika s poliartikularnim juvenilnim idiopatskim artritisom u dobi od 2 do <4 godine.
English: The long halflife of adalimumab should be taken into consideration if a surgical procedure is planned.
Croatian: Pri planiranju operacija treba voditi računa o dugom poluvijeku adalimumaba.
English: • If new skin lesions appear during or after therapy or if existing lesions change appearance, tell your doctor.
Croatian: • Ako se za vrijeme terapije ili nakon nje na koži jave nova oštećenja ili ako se izgled postojećih oštećenja promijeni, javite se liječniku.
English: Hidradenitis Suppurativa Clinical Response (HiSCR)
Croatian: Hidradenitis Suppurativa Clinical Response
English: • diverticulitis (inflammation and infection of the large intestine)
Croatian: • divertikulitis (upala i infekcija debelog crijeva)
English: Clinical remission (defined as Mayo score ≤ 2 with no subscore > 1) was assessed at Week 8.
Croatian: Klinička remisija (definirana kao Mayo rezultat ≤ 2 bez podrezultata > 1)
English: Patients demonstrating a Pediatric ACR 30 response at Week 16 were eligible to be randomised into the double blind (DB) phase and received either Humira 24 mg/m up to a maximum of 40 mg, or placebo every other week for an additional 32 weeks or until disease flare.
Croatian: Bolesnici koji su u 16. tjednu pokazali pedijatrijski odgovor ACR 30 (American College of Rheumatology 30) mogli su biti randomizirani u dvostruko slijepu fazu ispitivanja i primati ili 24 mg/m2 lijeka Humira, do maksimalne doze od 40 mg, ili placebo, svaki drugi tjedan kroz 32 tjedna ili do razbuktavanja bolesti.
English: The other ingredients are mannitol, citric acid monohydrate, sodium citrate, sodium dihydrogen phosphate dihydrate, disodium phosphate dihydrate, sodium chloride, polysorbate 80, sodium hydroxide and water for injections.
Croatian: Drugi sastojci su manitol, citratna kiselina hidrat, natrijev citrat, natrijev dihidrogenfosfat dihidrat, natrijev hidrogenfosfat dihidrat, natrijev klorid, polisorbat 80, natrijev hidroksid i voda za injekcije.
English: Squeeze the skin at your injection site with your other hand to make a raised area and hold it firmly until the injection is complete.
Croatian: Drugom rukom uhvatite nabor kože na mjestu ubrizgavanja kako biste dobili izbočinu i čvrsto ga držite dok ubrizgavanje nije završeno.
English: Clear Liquid in Syringe
Croatian: Prozorčić Bistra tekućina u štrcaljki
English: The efficacy of Humira was assessed in a randomised, double-blind, controlled study of 114 paediatric patients from 4 years of age with severe chronic plaque psoriasis (as defined by a PGA ≥ 4 or > 20% BSA involvement or > 10% BSA involvement with very thick lesions or PASI ≥ 20 or ≥ 10 with clinically relevant facial, genital, or hand/ foot involvement) who were inadequately controlled with topical therapy and heliotherapy or phototherapy.
Croatian: Djelotvornost lijeka Humira ocjenjivala se u randomiziranom, dvostruko slijepom, kontroliranom ispitivanju provedenom u 114 pedijatrijskih bolesnika u dobi od 4 ili više godina s teškom kroničnom plak psorijazom (koja se definirala kao PGA rezultat od ≥ 4 ili zahvaćenost površine tijela od > 20% ili zahvaćenost površine tijela od > 10% uz vrlo debele lezije ili PASI rezultat od ≥ 20 ili ≥ 10 uz klinički značajnu zahvaćenost lica, genitalija ili šaka/stopala) u kojih bolest nije bila dovoljno dobro kontrolirana topikalnom terapijom i helioterapijom ili fototerapijom.
English: All patients, and in particular patients with a medical history of extensive immunosuppressant therapy or psoriasis patients with a history of PUVA treatment should be examined for the presence of nonmelanoma skin cancer prior to and during treatment with Humira.
Croatian: Sve bolesnike, a posebno one koji u anamnezi imaju opsežnu imunosupresivnu terapiju ili bolesnike s psorijazom i PUVA liječenjem u anamnezi, potrebno je prije i za vrijeme liječenja lijekom Humira pregledavati u svrhu otkrivanja nemelanomskog karcinoma kože.
English: • Check that the small black needle cover of the syringe has been removed with the cap
Croatian: • Provjerite da je zajedno s kapicom uklonjen i mali crni pokrov igle na štrcaljki
English: • hepatosplenic T-cell lymphoma (a rare blood cancer that is often fatal)
Croatian: • hepatosplenični T-stanični limfom (rijetki rak krvi, često sa smrtnim ishodom)
English: Humira is used to treat polyarticular juvenile idiopathic arthritis and enthesitis-related arthritis.
Croatian: Humira je namijenjena liječenju poliartikularnog juvenilnog idiopatskog artritisa i artritisa povezanog s entezitisom.
English: In patients with paediatric psoriasis, anti-adalimumab antibodies were identified in 5/38 subjects (13%) treated with 0.8 mg/kg adalimumab monotherapy.
Croatian: U pedijatrijskih bolesnika s psorijazom, protutijela na adalimumab nađena su u 5/38 ispitanika (13%) liječenih monoterapijom adalimumabom u dozi od 0,8 mg/kg.
English: were observed at a rate (95% confidence interval) of 6.8 (4.4, 10.5) per 1,000 patient-years among 5,291 Humira treated patients versus a rate of 6.3 (3.4, 11.8) per 1,000 patient-years among 3,444 control patients (median duration of treatment was 4.0 months for Humira and 3.8 months for control-treated patients).
Croatian: 6,8 (4,4; 10,5) na 1000 bolesnik-godina (interval pouzdanosti od 95%) u 5291 bolesnika liječenog lijekom Humira, naspram 6,3 (3,4; 11,8) na 1000 bolesnik-godina u 3444 bolesnika iz kontrolne skupine (medijan trajanja terapije bio je 4,0 mjeseci u bolesnika liječenih lijekom Humira i 3,8 mjeseci u kontrolnoj skupini bolesnika).
English: • Merkel cell carcinoma (a type of skin cancer)
Croatian: • karcinom Merkelovih stanica (vrsta raka kože)
English: • pleural effusion (abnormal collection of fluid in the pleural space)
Croatian: • pleuralna efuzija (abnormalno nakupljanje tekućine u pleuralnom prostoru)
English: The 1 pre-filled pen pack comes with 2 alcohol pads (1 spare).
Croatian: Pakiranje s jednom napunjenom brizgalicom dolazi s 2 jastučića natopljena alkoholom (1 rezervni).
English: Enrolled patients were either current users of Humira 40 mg/0.8 ml and rated their average injection site pain as at least 3 cm (on a 0-10 cm VAS) or were biologic-naïve subjects who were starting Humira 40 mg/0.8 ml.
Croatian: Uključeni bolesnici su ili već tada primali lijek Humira u dozi od 40 mg/0,8 ml i ocijenili prosječnu bol na mjestu primjene kao najmanje 3 cm (prema vizualnoj analognoj ljestvici [engl. visual analogue scale, VAS] od 0-10 cm) ili prethodno nisu primali biološke lijekove i započeli su liječenje lijekom Humira u dozi od 40 mg/0,8 ml.
English: 4) Throwing away supplies
Croatian: 4) Odlaganje pribora u otpad
English: • oedema (swelling)
Croatian: • edem (oteklina)