FrancophonIA/ELRC3.0 huggingface dataset:
English: Alternative aetiologies should always be sought and Clostridium difficile enterocolitis be proven.
Maltese: Aetiologies alternattivi għandhom dejjem jiġu mfittxija u għandu jiġi ppruvat Clostridium difficile enterocolitis.
English: Peritoneal dialysis-associated peritonitis
Maltese: Peritonjum peritoneali assoċjati mad-dijalisi
English: 4 to 6 weeks***
Maltese: 4 sa 6 ġimgħat ***
English: Renal dysfunction delays the excretion of vancomycin.
Maltese: Disfunzjoni renali jittardja l-eliminazzjoni ta' vancomycin.
English: Orally administered Vancomycin capsules are not effective for other types of infections.
Maltese: Kapsuli vancomycin amministrati oralment mhumiex effettivi għal tipi oħra ta 'infezzjonijiet.
English: Vancomycin is primarily cleared by glomerular filtration.
Maltese: Vancomycin jitneħħa primarjament permezz tal-filtrazzjoni glomerulari.
English: 1 - Use antibiotics only when prescribed.
Maltese: 1 - Uża antibijotiċi meta preskritti biss.
English: Vancomycin is indicated in all age groups for the treatment of the following infections (see sections 4.2, 4.4 and 5.1): - complicated skin and soft tissue infections (cSSTI) - bone and joint infections - community acquired pneumonia (CAP) - hospital acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP) - infective endocarditis
Maltese: Vankomiċin huwa indikat fil-gruppi kollha ta' età għat-trattament ta' l-infezzjonijiet li ġejjin (ara sezzjonijiet 4.2, 4.4 u 5.1): - infezzjonijiet kkumplikati tal-ġilda u tat-tessuti rotob (cSSTI). - infezzjonijiet ta' l-għadam u l-ġogi - pnewmonja li tittieħed mill-komunità (CAP) - pnewmonja akkwistata minn sptar (HAP), li jinkludu pnewmonja assoċjati ma' ventilaturi (VAP)
English: - Infection of the inside lining of the heart (endocarditis) and to prevent endocarditis in patients at risk when undergoing major surgical procedures - Infection in central nervous system.
Maltese: - Infezzjoni ta' ġewwa l-inforra tal-qalb (endocarditis) u biex jipprevjenu endocarditis fil-pazjenti f'riskju meta għaddejjin minn proċeduri kirurġiċi maġġuri - Infezzjoni fis-sistema nervuża ċentrali.
English: Tinnitus, possibly preceding onset of deafness, should be regarded as an indication to discontinue treatment.
Maltese: Tinnitus, possibilment jippreċedi il-bidu ta' nuqqas ta' smigħ, għandhom jitqiesu bħala indikazzjoni li jitwaqqaf it-trattament.
English: The administration of vancomycin by intraperitoneal injection during continuous ambulatory peritoneal dialysis has been associated with a syndrome of chemical peritonitis.
Maltese: L-amministrazzjoni tal-vankomiċin bl-injezzjoni intraperitonali matul dijalisi peritoneali ambulatory kontinwu ġiet assoċjata mal-sindromu ta ' l-peritonite kimika.
English: Vancomycin shall only be administered as slow intravenous infusion of at least one hour duration or at a maximum rate of 10 mg/min (whichever is longer) which is sufficiently diluted (at least 100 ml per 500 mg or at least 200 ml per 1000 mg) (see section 4.4).
Maltese: Il-Vankomiċin għandu jiġi amministrat biss bħala infużjoni bil-mod għal ta' l-anqas siegħa fit- tul jew bir-rata massima ta' 10 mg/min (skont liema huwa itwal) li tkun suffiċjentement dilwit (mill-inqas 100 ml għal kull 500 mg jew mill-inqas 200 ml għal kull 1000 mg) (ara sezzjoni 4.4).
English: The product information may be subsequently updated by the Member State competent authorities, in liaison with the Reference Member State, as appropriate, in accordance with the procedures laid down in Chapter 4 of Title III of Directive 2001/83/EC.
Maltese: L-informazzjoni tal-prodott tista' tiġi aġġornata sussegwentement mill-awtoritajiet kompetenti tal-Istati Membri, flimkien mal-Istat Membru ta' Referenza, kif xieraq, b'konformità mal-proċeduri stabbiliti f'Kapitlu 4 ta' Titolu III ta' Direttiva 2001/83/KE.
English: Advice/medical education
Maltese: Tagħrif/edukazzjoni medika
English: Vancomycin should be infused slowly in a dilute solution (2.5 to 5.0 mg/ml) at a rate no greater than 10 mg/min and over a period not less than 60 minutes to avoid rapid infusion-related reactions.
Maltese: Vankomiċin għandu jkun infuż bil-mod fis-soluzzjoni dilwita (2.5 sa 5.0 mg/ml) b'rata mhux akbar minn 10 mg/min u fuq il-perjodu mhux inqas minn 60 minuta biex jiġu evitati reazzjonijiet rapidi relatati mal-infużjoni.
English: Gram positive anaerobes
Maltese: Gram anaerobes pożittiv
English: The frequency of infusion-related reactions (hypotension, flushing, erythema, urticaria and pruritus) increases with the concomitant administration of anaesthetic agents (see section 4.5).
Maltese: Il-frekwenza ta' reazzjonijiet relatati mal-infużjoni (ipotensjoni, tal-flushing, eritema, urticaria u pruritus) iżid mal-amministrazzjoni konkomittenti ta' aġenti bil-loppju (ara sezzjoni 4.5).
English: In neonates, after intravenous administration, vancomycin volume of distribution varies between 0.38 and 0.97 L/kg, similar to adult values, while clearance varies between 0.63 and 1.4 ml/kg/min.
Maltese: Fil trabi tat-twelid, wara għoti fil-vini, il-volum vancomycin ta' distribuzzjoni tvarja bejn 0.38 u 0.97 L/kg, simili għall-valuri adulti, filwaqt tneħħija tvarja bejn 0.63 u 1.4 ml/kg/min.
English: Term neonates (from birth to 27 days of post-natal age) and preterm neonates (from birth to the expected date of delivery plus 27 days)
Maltese: Neonates tat-terminu (mit-twelid sa 27 jum ta' wara t-twelid) u neonates preterm (mit-twelid sad-data mistennija tat-twelid flimkien ma' 27 jum)
English: Vancomycin has a spectrum of antibacterial activity limited to Gram-positive organisms.
Maltese: Vankomiċin għandu spettru ta' attività kontra l-batterja limitata għal organiżmi gram-pożittivi.
English: Therefore adverse events following intake of capsules are unlikely.
Maltese: Għalhekk avvenimenti avversi wara t- teħid ta kapsuli huma improbabbli.
English: Adults and adolescents (from 12 years and older) The recommended dose is 125 mg every 6 hours.
Maltese: Adulti u adolexxenti (minn 12-il sena u anzjani) Id-doża rakkomandata hija 125 mg kull 6 siegħat.
English: The combination of vancomycin with an aminoglycoside antibiotic has a synergistic effect against many strains of Staphylococcus aureus, non-enterococcal group D-streptococci, enterococci and streptococci of the Viridans group.
Maltese: Il-kombinazzjoni tal-vankomiċin ma antibijotiku aminoglikosid għandha effett sinerġistiku kontra ħafna razez ta' Staphylococcus aureus, grupp mhux enterococcal D-streptococci, enterokocci u streptococci tal-grupp Viridans.
English: The safety profile is generally consistent among children and adult patients.
Maltese: Il-profil tas-sigurtà huwa ġeneralment konsistenti bejn il-pazjenti tfal u adulti.
English: Gram-negative bacteria are resistant.
Maltese: Il-bakterja Gram-negattivi huma reżistenti.
English: Rapid bolus administration (i.e. over several minutes) may be associated with exaggerated hypotension (including shock and, rarely, cardiac arrest), histamine like responses and maculopapular or erythematous rash (“red man's syndrome” or “red neck syndrome”).
Maltese: L-amministrazzjoni mgħaġġla tal-bolus (i.e. fuq diversi minuti) jistgħu jiġu assoċjati ma' ipotensjoni esaġerata (inklużi xokk u, rari, arrest kardjaku), rispons bħal ta' ħistamin u maculopapular jew erythematous ġeneralizzat ("sindromu tal-bniedem aħmar " jew "sindromu ta' l-għonq aħmar").
English: The adverse reactions listed below are defined using the following MedDRA convention and system organ class database:
Maltese: Ir-reazzjonijiet avversi elenkati hawn taħt huma definiti mid-dejtabejż tal-konvenzjoni MedDRA u sistema klassifika tal-organi li ġej:
English: The recommended dose is 15 to 20 mg/kg of body weight every 8 to 12 h (not to exceed 2 g per dose).
Maltese: Id-doża rrakkomandata hija 15 sa 20 mg/kg tal-piż tal-ġisem kull 8 sa 12 h (li ma jaqbiżx 2 g kull doża).
English: During or shortly after rapid infusion anaphylactic/anaphylactoid reactions including wheezing may occur.
Maltese: Matul jew ftit wara infużjoni rapida reazzjonijiet anaphylactic/anaphylactoid inklużi wheezing jistgħu iseħħu.
English: [For all vancomycin 125 mg capsule] <{(Invented) vancomycin 125mg capsule}>
Maltese: [Għal vancomycin 125 mg kapsula kollha] <{(Ivvintat) vancomycin kapsula 125mg}>
English: Resistant > 2 mg/L 1 The breakpoints are based on epidemiological cut-off values (ECOFFs), which distinguish wild-type isolates from those with reduced susceptibility.
Maltese: 1 Il-breakpoints huma ibbażati fuq valuri ta' qtugħ epidemiologiċi (ECOFFs), li jiddistingwu wild-type isolates minn dawk b'suxxettibilità mnaqqsa .
English: Susceptible ≤ 2 mg/L
Maltese: Suxxettibli ≤ 2 mg/ l
English: Dosage
Maltese: Dardir
English: 4.4 Special warnings and precautions for use
Maltese: 4.3 Kontro-indikazzjonijiet
English: Similarly, concomitant use with nephrotoxic agents such as aminoglycoside antibiotics, NSAIDs (e.g., ibuprofen for closure of patent ductus arteriosus) or amphotericin B is associated with an increased risk of nephrotoxicity (see section 4.5) and therefore more frequent monitoring of vancomycin serum levels and renal function is indicated.
Maltese: Bl-istess mod, użu konkomittenti b'aġenti nefrotossiċi bħal antibijotiċi aminoglycoside, NSAID (eż., ibuprofen għall-għeluq tad-ductus patenti arteriosus) jew amphotericin B huwa assoċjat ma' riskju miżjud tal-nefrotossiċità (ara sezzjoni 4.5) u għalhekk monitoraġġ aktar frekwenti tal-livelli tas-serum vankomiċin u l-funzjoni renali huwa indikat.
English: Vancomycin is indicated in all age groups for the treatment of Clostridium difficile infection (CDI) (see sections 4.2, 4.4 and 5.1).
Maltese: Vancomycin huwa indikat fil-gruppi kollha ta' età għat-trattament ta' infezzjonijiet Clostridium difficile (CDI) (ara sezzjonijiet 4.2, 4.4 u 5.1).
English: Therefore, the below mentioned adverse reactions and frequencies related to parenteral vancomycin administration are included.
Maltese: Għalhekk, irreazzjonijiet avversi msemmija hawn taħt u frekwenzi relatati mal-amministrazzjoni vancomycin parenterali huma inklużi.
English: [For all vancomycin 250 mg capsule] <{(Invented) vancomycin 250mg capsule}>
Maltese: [Għal vancomycin 250 mg kapsuli kollha] <{(Ivvintat) vancomycin kapsula 250mg}>
English: Plasma clearance is about 0.058 L/kg/h and kidney clearance about 0.048 L/kg/h.
Maltese: L/kg/s u t-tneħħija tal-kliewi dwar 0.048 L/kg/s.
English: The combination of vancomycin with a cephalosporin has a synergistic effect against some oxacillin-resistant Staphylococcus epidermidis strains, and the combination of vancomycin with rifampicin has a synergistic effect against Staphylococcus epidermidis and a partial synergistic effect against some Staphylococcus aureus strains.
Maltese: Il-kombinazzjoni tal-vankomiċin ma' cephalosporin għandha effett sinerġistiku kontra xi oxacillin li jiflaħ razez Staphylococcus epidermidis, u l-kombinazzjoni tal-vankomiċin ma' rifampicin ikollu effett sinerġistiku kontra Staphylococcus epidermidis u effett sinerġistiku parzjali kontra xi razez Staphylococcus aureus.
English: Vancomycin pharmacokinetics is not altered in patients with hepatic impairment.
Maltese: Farmakokinetika vankomiċin ma tinbidilx fil-pazjenti b'indeboliment epatiċi.
English: The elimination half-life of vancomycin is 4 to 6 hours in patients with normal renal function and 2.2-3 hours in children.
Maltese: In-nofs-ħajja ta' eliminazzjoni ta' vankomiċin huwa minn 4 sa 6 sigħat f'pazjenti b'funzjoni renali normali u 2.2-3 sigħat fit-tfal.
English: Inherently resistant All Gram negative bacteria
Maltese: Il-batterja kollha Gram negattiv
English: Vancomycin is an antibiotic that belongs to a group of antibiotics called “glycopeptides”.
Maltese: Vancomycin huwa antibijotiku li jappartjeni għal grupp ta' antibijotiċi msejħa "glikopeptidi".
English: Vancomycin displays concentration-independent activity with the area under the concentration curve (AUC) divided by the minimum inhibitory concentration (MIC) of the target organism as the primary predictive parameter for efficacy.
Maltese: Vankomiċin juri attività indipendenti mill-konċentrazzjoni maż-żona taħt il-kurva tal-konċentrazzjoni (AUC) diviż bil- konċentrazzjoni minima inibitorji (MIC) tal-organiżmu fil-mira kif il-parametru jitbassar primarja għall-effikaċja.
English: Continuous infusion: loading dose of 30 mg/kg followed by a maintenance dose of 1.5 mg/kg/bag in all exchanges.
Maltese: Infużjoni kontinwu: it-tagħbija ta' doża ta' 30 mg/kg segwita b' doża ta' manteniment ta' 1.5 mg/kg/borża fl-iskambji kollha.
English: If vancomycin is administered during a peritoneal dialysis intraperitoneally, approximately 30-65% reach the systemic cycle during the first 6 hours.
Maltese: Jekk vancomycin jingħata matul dijalisi peritoneali peritonew, madwar 30-65% jilħqu l-ċiklu sistemika matul l-ewwel 6 sigħat.
English: Dose adjustments in paediatric patients aged 1 year and older could be based on glomerular filtration rate estimated (eGFR) by the revised Schwartz formula: eGFR (mL/min/1.73m2 ) = (height cm x 0.413)/ serum creatinine (mg/dl) eGFR (mL/min/1.73m2)= (height cm x 36.2/serum creatinine (µmol/L) For neonates and infants below 1 year of age, expert advice should be sought as the revised Schwartz formula is not applicable to them.
Maltese: 73m2 ) = (tul cm x 0.413)/ serum creatinine (mg/dl) eGFR (mL/min/1.73m2)= (tul cm x 36.2/serum creatinine (µmol/L)
English: Neonates, infants and children less than 12 years old
Maltese: Neonates, trabi u tfal ta' inqas minn 12-il sena
English: [For all vancomycin 250 mg capsule] [The following wording to be reflected in this section] Each capsule contains 250mg vancomycin hydrochloride equivalent to 250,000IU vancomycin.
Maltese: [Għal vancomycin 250 mg kapsuli kollha] [Il-kliem li ġej għandu jiġi rifless f'din is-sezzjoni] Kull kapsula fiha 250mg vankomiċin hydrochloride ekwivalenti għal 250,000IU vancomycin.
English: Secondary development of resistance during therapy is rare.
Maltese: Zvilupp sekondarju ta' reżistenza waqt it-terapija hija rari.
English: Vancomycin is used in adults and adolescents from 12 years of age for the treatment of infections of the mucosa of the small and the large intestines with damage to the mucosae (pseudomembranous colitis), caused by the Clostridium difficile bacterium.
Maltese: Vankomiċin huwa użat fl-adulti u adolexxenti minn 12-il sena ta' età għat-trattament ta' l-infezzjonijiet tal-mukoża taż-żgħar u l-intestini kbira bi ħsara għall-mukożi tiegħu (pseudomembranous colitis), ikkawżat mill-Clostridium difficile bacterium.
English: Vancomycin is indicated in all age groups for the treatment of peritoneal dialysis-associated peritonitis (see sections 4.2, 4.4 and 5.1).
Maltese: Vankomiċin huwa indikat fil-gruppi kollha ta' età għat-trattament ta' peritonite peritonjali assoċjati mad-dijaliżi (ara sezzjonijiet 4.2, 4.4 u 5.1).
English: There is very little metabolism of the drug.
Maltese: Ftit hemm metaboliżmu tad-droga.
English: Acute tubular necrosis
Maltese: -Mhux nekrotizant
English: During multiple dosing of 250 mg every 8 hours for 7 doses, faecal concentrations of vancomycin, in volunteers, exceeded 100 mg/kg in the majority of samples.
Maltese: Matul dożaġġ multiplu ta' 250 mg kull 8 sigħat għal 7 dożi, il-konċentrazzjonijiet fekali ta' vankomiċin, f'voluntiera, qabżet 100 mg/kg filmaġġoranza tal-kampjuni.
English: - Being sick (throwing up), diarrhoea - Confusion, drowsiness, lack of energy, swelling, fluid retention, decreased urine - Rash with swelling or pain behind the ears, in the neck, groin, under the chin and armpits (swollen lymph nodes), abnormal blood and liver function tests - Rash with blisters and fever.
Maltese: - Tkun ma tiflaħx (tirremetti), dijarrea - Konfużjoni, ngħas, nuqqas ta' enerġija, nefħa, żamma ta' fluwidi, tnaqqis awrina - Raxx ma' nefħa jew uġigħ wara l-widnejn, fl-għonq, fil-groin, taħt il-geddum u l-idejn (minfuħin lymph nodes), demm anormali u testijiet tal-funzjoni tal-fwied - Raxx bl-infafet u deni.
English: In infants and older children, the volume of distribution ranges between 0.26-1.05 L/kg while clearance varies between 0.33-1.87 ml/kg/min.
Maltese: L/kg waqt l-awtorizzazzjoni tvarja bejn 0.33-1.87 ml/kg/min.
English: Therapeutic trough (minimum) vancomycin blood levels should normally be 10-20 mg/l, depending on the site of infection and susceptibility of the pathogen.
Maltese: L-inqas livelli terapewtiċi (minimu) ta' vankomiċin fid-demm għandhom normalment ikunu 10-20 mg/l,u jiddependu fuq is-sit tal-infezzjoni u suxxettibilità tal-patoġeni.
English: Respiratory, thoracic and mediastinal disorders: Common
Maltese: Disturbi respiratorji, toraċiċi u medjastanjali:
English: Vancomycin is poorly dialyzable by intermittent hemodialysis.
Maltese: Il-vankomiċin ma tantx jitneħħa mill-hemodialysis intermittenti.
English: In patients with multiple recurrences, consideration may be given to treat the current episode of CDI with vancomycin, 125 mg four times daily for 10 days followed by either tapering the dose, i.e., gradually decreasing it until 125 mg per day or a pulse regimen, i.e., 125-500 mg/day every 2-3 days for at least 3 weeks.
Maltese: Pazjenti b'rikorrenzi multipli, konsiderazzjoni għandha tingħata li l-episodju kurrenti tal-CDI jigi ttrattat bil-vankomiċin, 125 mg erba' darbiet kuljum għal 10 ijiem segwit minn jew tapering tad-doża, jiġifieri, li d-doża titnaqqas gradwalment sa 125 mg kull jum jew reġimen tal-polz, jiġifieri, 125 - 500 mg/ġurnata kull 2-3 ijiem għal mill-inqas 3 ġimgħat.
English: Acute bacterial meningitis (For parenteral formulations authorised for Acute bacterial meningitis)
Maltese: Meninġite batterjali akuta (Għal formulazzjonijiet parenterali awtorizzati għall-meningite batterjali akuta)
English: Peri-operative prophylaxis of bacterial endocarditis in all age groups The recommended dose is an initial dose of 15 mg/kg prior to induction of anaesthesia.Depending on the duration of surgery, a second vancomycin dose may be required.
Maltese: Profilassi peri-operattiv tal-endocarditis batterjali fil-gruppi kollha ta' età Id-doża rrakkomandata hija doża inizjali ta' 15 mg/kg qabel l-induzzjoni tal-Anestesija.
English: Serious and occasionally fatal hypersensitivity reactions are possible (see sections 4.3 and 4.8).
Maltese: Reazzjonijiet ipersensittivi serji u xi kultant fatali huma possibbli (ara s-sezzjonijiet 4.3 u 4.8).
English: Vancomycin capsules are indicated in patients 12 years and older for the treatment of Clostridium difficile infection (CDI) (see sections 4.2, 4.4 and 5.1).
Maltese: Kapsuli vancomycin huma indikati f'pazjenti minn 12-il sena l-fuq għat-trattament ta 'infezzjoni Clostridium difficile (CDI) (ara sezzjonijiet 4.2, 4.4 u 5.1).
English: Characteristics in specific groups
Maltese: Karatteristiċi fi gruppi speċifiċi
English: Flushing of the upper body (“red man syndrome”), exanthema and mucosal inflammation, pruritus, urticaria
Maltese: Fwawar tal-ġisem ("sindromu bniedem aħmar"), eksantema u infjammazzjoni mukosali, ħakk, urtikarja
English: Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 (see section
Maltese: Ipersensittività għas-sustanza attiva jew għal xi eċċipjenti elenkati fis-Sezzjoni 6.1 (ara sezzjoni 4.4).
English: QUALITATIVE AND QUANTITATIVE COMPOSITION [For all vancomycin 125 mg capsule] [The following wording to be reflected in this section] Each capsule contains 125mg vancomycin hydrochloride equivalent to 125,000IU vancomycin.
Maltese: U KWANTITATTIVA [Għal vancomycin 125 mg kapsula kollha] [Il-kliem li ġej għandu jiġi rifless f'din is-sezzjoni] Kull kapsula fiha 125mg vankomiċin hydrochloride ekwivalenti għal 125,000IU vancomycin.
English: Minimum inhibitory concentration (MIC) breakpoints established by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) are as follows:
Maltese: Punti ta' ksur tal-konċentrazzjoni inibitorja minima (MIC) stabbiliti mill-Kummissjoni Ewropea fuq Ittestjar ta' Suxxettibbilità Antimikrobjali (EUCAST) huma kif ġejjin:
English: After parenteral administration it is excreted almost completely as microbiologically active substance (approx. 75-90% within 24 hours) through glomerular filtration via the kidneys.
Maltese: 75-90% fi żmien 24 siegħa) permezz ta' filtrazzjoni glomerulari mill-kliewi.
English: 4 to 6 weeks*
Maltese: 4 sa 6 ġimgħat*
English: Vancomycin concentration generally increases proportionally with increasing dose.
Maltese: vankomiċin ġeneralment jiżdied proporzjonalment b'żieda fid-doża.
English: Due to the very low systemic absorption, dose adjustment is unlikely, unless substantial oral absorption may occur in case of inflammatory intestinal disorders or Clostridium difficile-induced pseudomembranous colitis (see section 4.4).
Maltese: Minħabba l-assorbiment sistemiku baxx ħafna, l-aġġustament fid-doża mhux probabbli, sakemm assorbiment orali sostanzjali jista' jseħħ fil-każ ta' disturbi intestinali infjammatorji jew kolite psewdomembranuża indottata minn Clostridium difficile (ara sezzjoni 4.4).
English: Cross-resistance with other glycopeptide antibiotics, such as teicoplanin, does occur.
Maltese: Reżistenza inkroċjata ma' antibijotiċi oħra glikopeptidi, bħal teicoplanin, iseħħ.
English: Dyspnoea, stridor Gastrointestinal disorders: Rare
Maltese: Qtugħ ta' nifs, stridor Disturbi Gastro- intestinali:
English: Re-dose based on levels*
Maltese: Doża mill-ġdid ibbażati fuq livelli*
English: Renal insufficiency manifested primarily by increased serum creatinine and serum urea
Maltese: Insuffiċjenza renali manifestat primarjament mill żieda fil-krejatinina fisserum u l-urea fis-serum
English: The usual infusion dose is 15 to 20 mg for each kg of body weight.
Maltese: Id-doża tas-soltu ta' infużjoni huwa 15 sa 20 mg għal kull kg tal-piż tal-ġisem.
English: The usual starting dose for adult patients is 15 to 20 mg/kg that could be administered every 24 hours in patients with creatinine clearance between 20 to 49 ml/min.
Maltese: Id-doża tal-bidu normaligħall-pazjenti adulti hija 15 sa 20 mg/kg li jistgħu jiġu amministrati kull 24 siegħa fil-pazjenti bir-rata tat-tneħħija tal-kreatinin ta' bejn 20 sa 49 ml/min.
English: Intraperitoneal antibiotics should be added to the dialysate using sterile technique.
Maltese: Amministrazzjoni intraperitonali l-antibijotiċi intraperitonali għandhom jiġu miżjuda mal-dialysate bl-użu ta ' teknika sterili.
English: Eosinophilia and systemic symptoms (DRESS syndrome), AGEP (Acute Generalized Exanthematous Pustulosis) Renal and urinary disorders: Common
Maltese: Exfoliative dermatitis, Stevens-Johnson syndrome, sindromu Lyell, IgA bullous dermatosis lineari Mhux magħrufa Eosinofilja u sintomi sistemiċi (sindromu DRESS), AGEP (Ġeneralizzata Exanthematous Pustulosis akuta) Mard tal- kliewi u tas- sistema urinarja:
English: The greater the renal impairment, the greater the risk of developing the adverse reactions associated with the parenteral administration of vancomycin.
Maltese: Aktar ma jkun hemm indeboliment tal-kliewi, iktar hemm riskju li jiżviluppaw ir-reazzjonijiet avversi assoċjati mal-amministrazzjoni parenterali ta' vancomycin.
English: Drug interactions with anti-motility agents and proton pump inhibitors
Maltese: Interazzjonijiet ta' droga ma' aġenti ta' kontra il-motilità u inibituri tal- pompa protoni
English: Reversible neutropenia usually starting one week or more after onset of intravenous therapy or after total dose of more than 25 g.
Maltese: Neutropenia riversibbli li normalment tibda ġimgħa jew aktar wara l-bidu tat-terapija intravinuża jew wara doża totali ta' aktar minn 25 g.