FrancophonIA/ELRC3.0 huggingface dataset:
English: No such enhancement was observed with gadoterate meglumine (Dotarem).
Slovenian: Pri gadoterat meglominu (Dotarem) tako povečanje ni bilo ugotovljeno.
English: Indeed there are two phases of liver MRI enhancement with GdCAs:
Slovenian: Magnetnoresonančno slikanje jeter, pri katerem se kontrast izboljša s sredstvi GdCA, je dejansko sestavljeno iz dveh faz:
English: In very rare cases they may be serious or fatal.
Slovenian: V zelo redkih primerih so lahko hudi ali smrtni.
English: This summary was last updated on 18/09/2015.
Slovenian: Povzetek je bil nazadnje posodobljen 18/09/2015.
English: A response is normally seen within three to four days.
Slovenian: Odziv je običajno opazen v treh do štirih dneh.
English: Treatment should be discontinued after 10 days if no improvement is seen.
Slovenian: Zdravljenje je treba prekiniti po 10 dneh, če ni opaznega izboljšanja.
English: The European Commission granted a marketing authorisation valid throughout the European Union, for RevitaCAM on 23/02/2012.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom RevitaCAM, veljavno po vsej Evropski uniji, odobrila dne 23/02/2012.
English: These generally occur within the first week of treatment and usually disappear once treatment has stopped.
Slovenian: Večinoma se pojavijo v prvem tednu zdravljenja in po navadi izginejo po prekinitvi zdravljenja.
English: Other information about RevitaCAM:
Slovenian: Druge informacije o zdravilu RevitaCAM:
English: If accidental exposure occurs, hands should be washed immediately with soap and water.
Slovenian: Če pride do nenamerne izpostavitve, si je treba roke takoj umiti z milom in vodo.
English: Hands should always be washed after administrating the medicine.
Slovenian: Po dajanju zdravila si je vedno treba umiti roke.
English: It can be used for chronic (long term) musculo-skeletal disorders and for acute (sudden and short-lived) disorders, for instance, due to injury.
Slovenian: Lahko se uporablja pri kroničnih (dolgotrajnih) mišično-skeletnih obolenjih in akutnih (nenadnih in kratkotrajnih) boleznih, npr. zaradi poškodbe.
English: What benefit has RevitaCAM shown during the studies?
Slovenian: Kakšne koristi je zdravilo RevitaCAM izkazalo med študijami?
English: It is available in pumps of different sizes (6 ml, 11 ml and 33 ml) delivering appropriate amounts of meloxicam for dogs of different weights.
Slovenian: Zdravilo je na voljo v razpršilnikih različnih velikosti (6 ml, 11 ml in 33 ml), ki odmerijo ustrezno količino meloksikama za različno težke pse.
English: For longer term treatment, the dose can be decreased to the lowest effective dose once a response has been seen.
Slovenian: Pri dolgotrajnejšem zdravljenju lahko, ko opazite odziv, odmerek prilagodite na najmanjši še učinkoviti odmerek.
English: RevitaCAM must not be used in dogs less than six weeks of age and should not be used in cats.
Slovenian: Ne sme se uporabljati pri psih, mlajših od šestih mesecev, in pri mačkah.
English: People who are hypersensitive to NSAIDs should avoid contact with RevitaCAM.
Slovenian: Osebe, ki so preobčutljive za nesteroidna protivnetna zdravila, naj se izogibajo stiku z zdravilom RevitaCAM.
English: It must not be used in dogs that are hypersensitive (allergic) to the active substance or to any of the other ingredients.
Slovenian: Ne sme se uporabljati pri psih, ki so preobčutljivi za (alergični na) zdravilno učinkovino ali katero koli drugo sestavino zdravila.
English: What is the risk associated with RevitaCAM?
Slovenian: Kakšna tveganja so povezana z zdravilom RevitaCAM?
English: RevitaCAM contains meloxicam, which belongs to a class of medicines called non-steroidal antiinflammatory drugs (NSAIDs).
Slovenian: Zdravilo RevitsCAM vsebuje meloksikam, ki spada v skupino zdravil, imenovanih nesteroidna protivnetna zdravila (NSPVZ).
English: As prostaglandins trigger inflammation, pain, exudation and fever, meloxicam reduces these signs and symptoms.
Slovenian: Prostaglandini povzročajo vnetje, bolečino, izločanje tekočine in povišano telesno temperaturo, meloksikam pa zmanjšuje obseg teh znakov in simptomov.
English: It is available as a 5 mg/ml oromucosal spray (a spray administered to the back of the mouth, towards the gums and /or inner cheek) for dogs.
Slovenian: Na voljo je kot oralno pršilo v odmerku 5 mg/ml (pršilo, ki se nanese na zadnji del gobca proti dlesnim in/ali notranji ličnici) za pse.
English: Treatment should be started at a single dose of 0.2 mg/kg body weight on the first day, and then continued at a maintenance dose of 0.1 mg/kg body weight once a day.
Slovenian: Velikost razpršilnika in število razprškov, ki jih je treba nanesti, sta odvisna od telesne mase psa. Zdravljenje se začne z enim odmerkom 0,2 mg/kg telesne mase prvi dan in nato nadaljuje z vzdrževalnim odmerkom 0,1 mg/kg telesne mase enkrat na dan. Pršilo se nanese v gobec psa, pršenje pa se usmeri nazaj in proti dlesnim in/ali notranjim ličnicam.
English: RevitaCAM is used in dogs to relieve inflammation and pain.
Slovenian: Zdravilo RevitaCAM se uporablja za ublažitev vnetja in bolečine pri psih.
English: Why has RevitaCAM been approved?
Slovenian: Zakaj je bilo zdravilo RevitaCAM odobreno?
English: Side effects sometimes seen with other NSAIDs, such as loss of appetite, vomiting, diarrhoea, blood appearing in the stools, renal (kidney) failure and apathy (lack of vitality) are occasionally seen with RevitaCAM.
Slovenian: Občasni neželeni učinki, opazni pri drugih nesteroidnih protivnetnih zdravilih, kot so izguba teka, bruhanje, driska, kri v blatu, ledvična odpoved in apatija (pomanjkanje vitalnosti), se včasih pojavijo tudi ob uporabi zdravila RevitaCAM.
English: Various studies looked at how RevitaCAM was absorbed and its effects in the body, in comparison with Metacam.
Slovenian: V več študijah so proučevali, kako se zdravilo RevitaCAM v primerjavi z zdravilom Metacam absorbira v telesu in kako v njem deluje.
English: Consequently, RevitaCAM's benefit is taken as being the same as that of the reference medicine.
Slovenian: Zaradi tega velja, da so njegove koristi enake kot pri referenčnem zdravilu.
English: RevitaCAM is similar to Metacam oral solution containing the same active substance, but given in a different way, as an oromucosal spray.
Slovenian: Podobno je peroralni raztopini zdravila Metacam, ki vsebuje isto zdravilno učinkovino, a se daje drugače, kot oralno pršilo.
English: RevitaCAM is a medicine that contains the active substance meloxicam.
Slovenian: RevitaCAM je zdravilo, ki vsebuje zdravilno učinkovino meloksikam.
English: What is RevitaCAM used for?
Slovenian: Za kaj se zdravilo RevitaCAM uporablja?
English: The CVMP considered that, in accordance with European Union requirements, RevitaCAM has been shown to be bioequivalent to Metacam.
Slovenian: CVMP je ugotovil, da je zdravilo RevitaCAM v skladu z zahtevami Evropske unije biološko enakovredno zdravilu Metacam.
English: In some dogs sneezing, coughing, gagging or drooling may be seen immediately after treatment administration.
Slovenian: Pri nekaterih psih so takoj po dajanju zdravila opazili kihanje, kašljanje, davljenje ali slinjenje.
English: RevitaCAM must not be used in dogs with liver, heart or kidney problems, bleeding disorders, or dogs suffering from irritation or ulcers of the digestive tract.
Slovenian: Zdravilo RevitaCAM se ne sme uporabljati pri psih z okvarjenim delovanjem jeter, srca ali ledvic, krvavitvami ali tistimi, ki imajo razdražena prebavila ali razjede v prebavilih.
English: RevitaCAM should not be used in pregnant or lactating animals.
Slovenian: Ne sme se uporabljati pri brejih živalih ali živalih v laktaciji.
English: Therefore the CVMP's view was that, as for Metacam, RevitaCAM's benefits are greater than its risks when used for the approved indications and the
Slovenian: Zato je menil, da so njegove koristi , tako kot pri zdravilu Metacam, večje od z njim povezanih tveganj pri uporabi za odobrene indikacije, in priporočil, da se zanj odobri dovoljenje za promet.
English: How has RevitaCAM been studied?
Slovenian: Kako je bilo zdravilo RevitaCAM raziskano?
English: Studies provided for RevitaCAM were tests to determine that it is bioequivalent to the reference medicine, Metacam.
Slovenian: Predložene študije v podporo zdravilu RevitaCAm so bila preskušanja za ugotavljanje, ali je biološko enakovredno zdravilu Metacam.
English: What is RevitaCAM?
Slovenian: Kaj je zdravilo RevitaCAM?
English: Based on the findings of the study, RevitaCAM was considered to be bioequivalent to the reference medicine.
Slovenian: V študiji je bilo ugotovljeno, da je zdravilo RevitaCAM biološko enakovredno referenčnemu zdravilu.
English: How does RevitaCAM work?
Slovenian: Kako zdravilo RevitaCAM deluje?
English: The final opinion was converted into a decision by the European Commission on 9 September 2008.
Slovenian: Končno mnenje je bilo spremenjeno v odločbo Evropske komisije dne 9. septembra 2008.
English: Written explanations were provided by the MAHs on 14 December 2008, 5 May 2008, 12 June 2008 and 20 June 2008.
Slovenian: Imetniki dovoljenja za promet z zdravilom so pisna pojasnila poslali 14. decembra 2007, 5. maja 2008, 12. junija 2008 in 20. junija 2008.
English: During the February 2008 plenary meeting Dr. Rafe Survana was appointed Co-Rapporteur, replacing Dr. Matthew Thatcher.
Slovenian: Med plenarnim zasedanjem februarja 2008 je bil za soporočevalca imenovan dr. Rafe Survana, ki je zamenjal dr. Matthewa Thatcherja.
English: London, 23 October 2008 EMEA/438258/2008
Slovenian: London, 23. oktober 2008 EMEA/CHMP/619546/2008
English: ∗ Notes: the information given in this document and its annexes reflects only the CHMP opinion dated 26 June 2008.
Slovenian: ∗ Opombe: Informacije, podane v tem dokumentu in dodatkih, odražajo zgolj mnenje CHMP z dne 26. junija 2008.
English: Healthcare professionals were to be reminded of these measures through a communication letter (Dear Healthcare Professional Letter).
Slovenian: Zdravstveni delavci bodo o teh ukrepih opozorjeni s posebnim dopisom („Spoštovani zdravstveni delavec“).
English: The arbitration procedure was discussed by the CHMP at its plenary meeting in September 2007 and a Rapporteur (Dr. Karl Broich) and Co-Rapporteur (Dr. Matthew Thatcher) were appointed.
Slovenian: Arbitražni postopek je CHMP obravnaval na svojem plenarnem zasedanju septembra 2007, imenovana pa sta bila tudi poročevalec (dr. Karl Broich) in soporočevalec (dr. Matthew Thatcher).
English: As these concerns were not resolved during the course of the procedure, a notification of an official referral for arbitration under Article 6(12) of Commission Regulation EC No 1084/2003 to the CHMP was made by France on 19 September 2007.
Slovenian: Ker ti zadržki niso med postopkom niso bili odpravljeni, je Francija 19. septembra 2007 CHMP poslala obvestilo o uradni napotitvi na arbitražo v skladu s členom 6(12) Uredbe Komisije (ES) št. 1084/2003.
English: COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) OPINION FOLLOWING AN ARTICLE 6 (12) REFERRAL Arcoxia International non-proprietary name (INN): etoricoxib BACKGROUND INFORMATION *
Slovenian: ODBOR ZA ZDRAVILA ZA UPORABO V HUMANI MEDICINI (CHMP) MNENJE V ZVEZI Z NAPOTITVIJO V SKLADU S ČLENOM 6(12) ZA zdravilo Arcoxia Mednarodno nelastniško ime (INN): etorikoksib OSNOVNE INFORMACIJE*
English: The list of product names concerned is given in Annex I. The scientific conclusions are provided in Annex II, the amended product information in Annex III and the conditions of the marketing authorisation in Annex IV.
Slovenian: Seznam zadevnih imen zdravil je naveden v Dodatku I. Znanstveni zaključki so podani v Dodatku II, spremenjene informacije o zdravilu v Dodatku III, pogoji dovoljenja za promet z zdravilom pa v Dodatku IV.
English: France considered that a review of the benefit/risk profile of Arcoxia was needed.
Slovenian: Francija je ocenila, da je potrebna presoja profila razmerja med koristmi in tveganjem zdravila Arcoxia.
English: At the end of the mutual recognition procedure, there was a discrepancy between different European Union (EU) Member States regarding the safety of etoricoxib at the 90mg dose in the new proposed indication.
Slovenian: Ob koncu postopka medsebojnega priznavanja se je med različnimi državami članicami Evropske unije (EU) pojavila neskladnost glede varnosti etorikoksiba v 90-miligramskem odmerku v novi predlagani indikaciji.
English: It was therefore difficult to determine risks for etoricoxib compared with ibuprofen, ketoprofen or other less-commonly used NSAIDs.
Slovenian: Zato je težko določiti tveganja v zvezi z etorikoksibom v primerjavi z ibuprofenom, ketoprofenom ali drugimi, manj pogosto uporabljenimi nesteroidnimi protivnetnimi zdravili.
English: The CHMP therefore recommended that dose finding studies should be explored to conclude if treatment with 60mg once daily would also be adequate for some patients.
Slovenian: Zato CHMP priporoča, da se študije o odmerjanju posebej proučijo za ugotovitev, ali bi zdravljenje s 60-miligramskim odmerkom enkrat dnevno zadostovalo za določene bolnike.
English: The referral procedure was initiated on 20 September 2007 with the adoption of a CHMP list of questions that were to be addressed by the marketing authorisation holders (MAHs).
Slovenian: Napotitveni postopek se je začel 20. septembra 2007 s sprejetjem seznama vprašanj CHMP, na katera so morali odgovoriti imetniki dovoljenja za promet z zdravilom.
English: The CHMP concluded that the data confirmed the known renovascular safety profile of etoricoxib (hypertension, oedema and congestive heart failure).
Slovenian: CHMP je zaključil, da podatki potrjujejo znan renovaskularni varnostni profil etorikoksiba (povišan krvni tlak, edemi in kongestivna odpoved srca).
English: Etoricoxib is a selective inhibitor of COX-2 (cyclooxygenase 2) indicated in the symptomatic relief of osteoarthritis (OA, 30-60mg once daily (od)), rheumatoid arthritis (RA, 90mg od) and the pain and signs of inflammation associated with acute gouty arthritis (120mg od).
Slovenian: Etorikoksib je selektivni zaviralec COX-2 (ciklooksigenaze-2), indiciran za simptomatsko lajšanje osteoartritisa (30-60 mg enkrat dnevno), revmatoidnega artritisa (90 mg enkrat dnevno) ter bolečin in vnetij, povezanih z akutnim protinskim artritisom (120 mg enkrat dnevno).
English: There was little direct comparative safety data for individual non-steroidal anti-inflammatory drugs (NSAIDs) other than diclofenac and naproxen.
Slovenian: Obstaja zelo malo neposrednih primerjalnih podatkov o varnosti posameznih nesteroidnih protivnetnih zdravil, razen za diklofenak in naproksen.
English: The CHMP therefore recommended the strengthening of the contraindication in hypertensive patients and alerts prescribers that blood pressure needs to be monitored, especially
Slovenian: CHMP zato priporoča okrepitev kontraindikacije pri bolnikih s povišanim krvnim tlakom in zdravstvene delavce, ki zdravilo predpisujejo, opozarja, da je treba krvni tlak nadzorovati, zlasti v obdobju dveh tednov po uvedbi zdravljenja.
English: This referral procedure relates to a request for arbitration concerning a type II variation for a new indication to include treatment of ankylosing spondylitis (AS), at a recommended daily dose of 90mg.
Slovenian: Ta napotitveni postopek se nanaša na vlogo za arbitražo v zvezi s spremembo tipa II glede nove indikacije, da bi se vključilo zdravljenje ankilozirajočega spondilitisa s priporočenim dnevnim 90miligramskim odmerkom.
English: Based on the review of the available data, the CHMP considered that the benefits of etoricoxib outweigh the risks in the treatment of ankylosing spondylitis.
Slovenian: Na podlagi pregleda dostopnih podatkov je CHMP menil, da koristi etorikoksiba pri zdravljenju ankilozirajočega spondilitisa odtehtajo z njim povezana tveganja.
English: The main unresolved areas of concern identified by France were concerns regarding long term safety of a daily dose of 90mg etoricoxib in the view of possible increased cardiovascular (CV) risk related to the use of the 90mg dose in the ankylosing spondylitis (AS) indication.
Slovenian: Glavna nerešena vprašanja, ki jih je izpostavila Francija, so se nanašala na varnost dolgotrajne uporabe 90-miligramskega dnevnega odmerka etorikoksiba zaradi možnega povečanega tveganja za srce in ožilje, povezanega z uporabo 90-miligramskega odmerka pri indikaciji ankilozirajočega spondilitisa.
English: On 26 June 2008, the CHMP, having considered the data provided by the MAHs, recommended the granting of the variation to the marketing authorisations.
Slovenian: CHMP je po proučitvi podatkov, ki so jih poslali imetniki dovoljenja za promet z zdravilom, 26. junija 2008 priporočil odobritev spremembe dovoljenj za promet z zdravilom.
English: Data from clinical studies showed clinically meaningful treatment effect for the 90mg etoricoxib once daily dose for AS indication; however, some data are available to indicate that lower doses might also show effect.
Slovenian: Podatki iz kliničnih študij so pokazali klinično pomembne učinke zdravljenja z 90-miligramskim odmerkom etorikoksiba enkrat dnevno pri indikacijah ankilozirajočega spondilitisa, na voljo pa so tudi podatki, ki kažejo, da so lahko tudi manjši odmerki učinkoviti.
English: The data further confirmed a similar CV thrombotic risk like diclofenac and some degree of upper gastrointestinal (GI) safety advantage over naproxen and diclofenac (though no particular lower GI safety advantage).
Slovenian: Podatki so potrdili podobno trombotično kardiovaskularno ogroženost kot pri uporabi učinkovine diklofenak in nekoliko večjo varnost glede ogroženosti zgornjih prebavil v primerjavi z učinkovinama naproksen in diklofenak (vendar nobene manjše ogroženosti za spodnja prebavila).
English: This is a summary of the European public assessment report (EPAR) for Glyxambi.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Glyxambi.
English: The full EPAR for Glyxambi can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila Glyxambi je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: The Agency's Committee for Medicinal Products for Human Use (CHMP) decided that Glyxambi's benefits are greater than its risks and recommended that it be approved for use in the EU.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) pri agenciji je zaključil, da so koristi zdravila Glyxambi večje od z njim povezanih tveganj, in priporočil, da se odobri za uporabo v EU.
English: Empagliflozin has been authorised in the European Union (EU) as Jardiance since 2014.
Slovenian: Empagliflozin je v Evropski uniji (EU) odobren od leta 2014 kot zdravilo Jardiance.
English: • Linagliptin is a dipeptidyl-peptidase-4 (DPP-4) inhibitor.
Slovenian: • Linagliptin je zaviralec dipeptidil-peptidaze-4 (DPP-4).
English: What measures are being taken to ensure the safe and effective use of Glyxambi?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Glyxambi?
English: Empagliflozin / linagliptin
Slovenian: Glyxambi empagliflozin/linagliptin
English: The most common side effects with Glyxambi (which may affect more than 7 in 100 people) are urinary infections.
Slovenian: Najpogostejši neželeni učinki zdravila Glyxambi (ki se lahko pojavijo pri več kot 7 bolnikih od 100) so okužbe sečil.
English: Empagliflozin in combination with linagliptin (the same combination as in Glyxambi) was evaluated in 3 main studies involving 1,221 adults with type 2 diabetes.
Slovenian: Empagliflozin so v kombinaciji z linagliptinom (kar je enaka kombinacija kot v zdravilu Glyxambi) ocenjevali v treh glavnih študijah, ki so vključevale 1 221 odraslih s sladkorno boleznijo tipa 2.
English: The HbA1c levels were around 8% before treatment.
Slovenian: Raven HbA1c pred zdravljenjem je bila približno 8 %.
English: Other information about Glyxambi
Slovenian: Druge informacije o zdravilu Glyxambi
English: HbA1c levels were just below 8% at the start of the study.
Slovenian: Raven HbA1c je na začetku študije znašala nekoliko manj kot 8 %.
English: It contains two active substances, empagliflozin and linagliptin.
Slovenian: Vsebuje dve zdravilni učinkovini, empagliflozin in linagliptin.
English: • patients who are already taking empagliflozin and linagliptin as separate tablets.
Slovenian: • pri bolnikih, ki že jemljejo empagliflozin in linagliptin v obliki ločenih tablet.
English: The most serious side effects are ketoacidosis (high blood levels of acids called ‘ketoacids'), pancreatitis (inflammation of the pancreas), hypersensitivity (allergic reactions) and hypoglycaemia (low blood sugar levels).
Slovenian: Najresnejši neželeni učinki so ketoacidoza (visoka koncentracija ketokislin v krvi), pankreatitis (vnetje trebušne slinavke), preobčutljivost (alergijske reakcije) in hipoglikemija (nizke ravni sladkorja v krvi).
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Glyxambi have been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in varnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Glyxambi upoštevati zdravstveni delavci in bolniki, so vključeni v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo.
English: For more information about treatment with Glyxambi, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Glyxambi preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: Patients were then given either empagliflozin or placebo (a dummy treatment) in addition to their existing treatment.
Slovenian: Bolniki so nato poleg obstoječega zdravljenja prejemali empagliflozin ali placebo (zdravilo brez zdravilne učinkovine).
English: Glyxambi must not be used in people who are hypersensitive (allergic) to empagliflozin, linagliptin, any of the other ingredients or who have ever had a serious allergic reaction to any DPP-4 or SGLT2 inhibitor.
Slovenian: Zdravila Glyxambi ne smejo uporabljati osebe, ki so preobčutljive za (alergične na) empagliflozin, linagliptin ali katero koli drugo sestavino zdravila ali pri katerih se je kdaj v preteklosti pojavila huda alergijska reakcija na zaviralec DPP-4 ali SGLT2.
English: What benefits of Glyxambi have been shown in studies?
Slovenian: Kakšne koristi je zdravilo Glyxambi izkazalo v študijah?
English: Linagliptin has been authorised in the EU as Trajenta since
Slovenian: Linagliptin je v EU odobren od leta 2011 kot zdravilo Trajenta.
English: • patients whose blood glucose levels are not controlled well enough by a combination of one of Glyxambi's active substances (empagliflozin or linagliptin) with other diabetes medicines (metformin and/or a sulphonylurea);
Slovenian: • pri bolnikih, pri katerih ravni glukoze v krvi ni mogoče dobro uravnavati s kombinacijo ene od zdravilnih učinkovin zdravila Glyxambi (empagliflozina ali linagliptina) in drugih zdravil za zdravljenje sladkorne bolezni (metformina in/ali sulfonilsečnine);
English: What are the risks associated with Glyxambi?
Slovenian: Kakšna tveganja so povezana z zdravilom Glyxambi?
English: Glyxambi is used in the following groups:
Slovenian: Zdravilo Glyxambi se uporablja pri naslednjih skupinah bolnikov:
English: Adding linagliptin to treatment with empagliflozin and metformin for 24 weeks reduced HbA1c levels from 7.8% to 7.2%, compared with a reduction from 7.9% to 7.7% when placebo was added.
Slovenian: Po 24 tednih dodajanja linagliptina zdravljenju z empagliflozinom in metforminom se je raven HbA1c znižala s 7,8 % na 7,2 % v primerjavi z zmanjšanjem s 7,9 % na 7,7 % pri dodajanju placeba.
English: • Empagliflozin works by blocking a protein in the kidneys called sodium-glucose co-transporter 2 (SGLT2).
Slovenian: • Empagliflozin zavira beljakovino v ledvicah, imenovano natrijev glukozni koprenašalec 2 (SGLT2).