FrancophonIA/ELRC3.0 huggingface dataset:
English: • Non-steroidal anti-inflammatory drugs (e.g., ibuprofen, diclofenac) (used for treating pain and
Danish: • Non-steroide anti-inflammatoriske lægemidler (f.eks. ibuprofen og diclofenac) (bruges til behandling af smerter og betændelsestilstande)
English: Infections and infestations sinusitis pseudomembranou s colitis
Danish: Infektioner og parasitære sygdomme sinusitis pseudomembranøs colitis
English: During oral administration of 200 mg or 300 mg twice daily for 14 days in patients at risk of aspergillosis (mainly patients with malignant neoplasms of lymphatic or haematopoietic tissue), the observed pharmacokinetic characteristics of rapid and consistent absorption, accumulation and nonlinear pharmacokinetics were in agreement with those observed in healthy subjects.
Danish: Ved oral administration af 200 mg eller 300 mg 2 gange dagligt i 14 dage hos patienter med risiko for aspergillose (hovedsageligt patienter med ondartede svulster i det lymfatiske eller hæmatopoetiske væv) svarede de observerede farmakokinetiske karakteristika af hurtig og ensartet absorption, akkumulering og ikke-lineær farmakokinetik til, hvad man har observeret hos raske forsøgspersoner.
English: [non-specific CYP450 inhibitor and increases gastric pH]
Danish: [non-specifik CYP450 hæmmer og øger gastrisk pH]
English: Based on the population pharmacokinetic analysis, 12 to 14 year old adolescents weighing less than 50 kg should receive children's doses (sees ection4.2).
Danish: Baseret på den farmakokinetiske populationsanalyse skal 12-14 årige unge, der vejer <50 kg have børnedosis (se pkt.
English: AUCτ, AUCt and AUC0-∞represent area under the curve over a dosing interval, from time zero to the time with detectable measurement and from time zero to infinity, respectively.
Danish: AUCτ, AUCt og AUC0--∞ angiver de respektive arealer under plasmakoncentrationstidskurven inden for et dosisinterval, til den sidst kvantificerbare måling samt fra tiden 0 til uendelig.
English: In an oral single dose (200 mg) study in subjects with normal renal function and mild (creatinine clearance 41-60 ml/min) to severe (creatinine clearance < 20ml/min) renal impairment, the pharmacokinetics of voriconazole were not significantly affected by renal impairment.
Danish: I et oralt enkeltdosisstudie (200 mg) hos patienter med normal nyrefunktion og mild (kreatinin clearance 41-60 ml/min) til svært nedsat nyrefunktion (kreatinin clearance < 20 ml/min) var voriconazols farmakokinetik ikke signifikant påvirket af nedsat nyrefunktion.
English: All other adolescents (12 to 14 years and ≥50 kg; 15 to 17 years regardless of body weight)
Danish: Øvrige unge (12-14 år og ≥ 50 kg; 15-17 år uanset legemsvægt)
English: Other HIV Protease Inhibitors (e.g., saquinavir, amprenavir and nelfinavir)*
Danish: Andre hiv-proteasehæmmere (f.eks. saquinavir, amprenavir og nelfinavir)*
English: Hypromellose Titanium dioxide (E171) Lactose monohydrate Triacetin
Danish: Filmovertræk Hypromellose Titandioxid (E171) Lactosemonohydrat Triacetin
English: Frequent monitoring for adverse reactions and toxicity related to methadone, including QTc prolongation, is recommended.
Danish: Hyppig monitorering for methadon-relaterede bivirkninger og toksicitet, herunder forlængelse af QTc-intervallet, anbefales.
English: This represents a heterogeneous population, containing patients with haematological malignancy, HIV infected patients with oesophageal candidiasis and refractory fungal infections, non-neutropenic patients with candidaemia or aspergillosis and healthy volunteers.
Danish: Databasen repræsenterer en heterogen population indeholdende patienter med maligne hæmatologiske sygdomme, HIV-inficerede patienter med øsofageal candidiasis og refraktære svampeinfektioner, non-neutropene patienter med candidæmi eller aspergillosis og raske forsøgspersoner.
English: No significant differences in Cmax and AUCτ were observed between healthy elderly females (≥65 years) and healthy young females (18-45 years).
Danish: Der blev ikke observeret nogen signifikante forskelle i Cmax og AUCτ mellem raske, ældre kvinder ( 65 år) og raske, unge kvinder (18-45 år).
English: If you are already being treated with rifabutin your blood counts and side effects to rifabutin will need to be monitored.
Danish: Hvis De allerede er i behandling med rifabutin er det nødvendigt, at tage blodprøver samt være opmærksom på bivirkninger forbundet med rifabutin.
English: Benzodiazepines (e.g., midazolam, triazolam, alprazolam)
Danish: Benzodiazepiner (f.eks. midazolam, triazolam, alprazolam)
English: The primary mode of action of voriconazole is the inhibition of fungal cytochrome P450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis.
Danish: Voriconazols primære virkningsmåde er hæmning af fungal cytochrom P-450-medieret 14-α-lanosteroldemethylering, der er et vigtigt trin i biosyntesen af fungal ergosterol.
English: Voriconazole should be dosed as adults.
Danish: Voriconazol doseres som til voksne.
English: Voriconazole has been shown to be more selective for fungal cytochrome P450 enzymes than for various mammalian cytochrome P-450 enzyme systems.
Danish: Voriconazol har vist sig mere selektiv for fungale cytochrom P-450 enzymsystemer end over for forskellige mammale cytochrom P-450 enzymsystemer.
English: The overall incidence of transaminase increases>3xULN (not necessarily comprising an adverse event) in the voriconazole clinical programme was 18.0% (319/1,768) in adults and 25.8% (73/283) in paediatric subjects who received voriconazole for pooled therapeutic and prophylaxis use.
Danish: I voriconazols kliniske program var den samlede incidens af transaminasestigninger > 3 × ULN (ikke nødvendigvis med bivirkninger) 18,0 % (319/1.768) hos voksne og 25,8 % (73/283) hos pædiatriske forsøgspersoner, der blev behandlet med voriconazol til samlet terapeutisk og profylaktisk brug.
English: A study has been conducted in healthy volunteers which examined the effect on QTc interval of single doses of voriconazole up to 4 times the usual daily dose.
Danish: Der er udført et klinisk studie hos raske frivillige forsøgspersoner, hvor effekten af voriconazolbehandling med enkeltdoser op til 4 gange den sædvanlige daglige dosis blev undersøgt på QT-intervallet.
English: Frequent monitoring for opiate-associated adverse reactions may be necessary (see section 4.5).
Danish: Hyppig monitorering for opiatrelaterede bivirkninger kan være nødvendig (se pkt.
English: Other treated fungal infections (often with either partial or complete response) included isolated cases of Alternaria spp., Blastomyces dermatitidis, Blastoschizomyces capitatus, Cladosporium spp., Coccidioides immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserohilum rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus,
Danish: Andre behandlede svampeinfektioner (ofte med enten delvist eller fuldstændigt respons) omfatter isolerede tilfælde af Alternaria spp., Blastomyces dermatitidis, Blastoschizomyces capitatus, Cladosporium spp., Coccidioides immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserholium rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus, Penicillium spp.
English: The recommended dose for children and teenagers is as follows:
Danish: Den anbefalede dosis til børn og teenagere:
English: • Phototoxicity
Danish: • Fototoksicitet
English: Ranitidine (150 mg BID)
Danish: Ranitidin (150 mg BID)
English: In reproduction studies, voriconazole was shown to be teratogenic in rats and embryotoxic in rabbits at systemic exposures equal to those obtained in humans with therapeutic doses.
Danish: I reproduktionsforsøg har voriconazol vist sig at være teratogent hos rotter og embryotoksisk hos kaniner ved systemisk optagelse svarende til den, der ses ved terapeutiske doser hos mennesker.
English: Voriconazole should be dosed as children as these young adolescents may metabolize voriconazole more similarly to children than to adults.
Danish: Til unge bør voriconazol doseres som til børn, da disse unge i højere grad metaboliserer voriconazol som børn end som voksne.
English: In the same study, no significant differences in Cmax and AUCτ were observed between healthy elderly males and healthy elderly females (≥65 years).
Danish: I samme studie blev der ikke observeret signifikante ændringer i Cmax og AUCτ mellem raske, ældre mænd og raske, ældre, kvinder ( 65 år).
English: Reminds HCPs to discuss with the patient/care giver the risks of phototoxicity/skin SCC and hepatotoxicity, what to look for, how and when to seek immediate attention.
Danish: - Påminde læger og sundhedspersonale om, at de skal drøfte risici for fototoksicitet/planocellulært hudkarcinom og levertoksicitet med patienter/omsorgspersoner, hvad de skal holde øje med, samt hvordan og hvornår de skal søge øjeblikkelig lægehjælp.
English: If patient response to treatment is inadequate, the maintenance dose may be increased to 300 mg twice daily for oral administration.
Danish: Hvis patientens respons på behandling er utilstrækkeligt, bør vedligeholdelsesdosis for oral administration øges til 300 mg 2 gange dagligt.
English: Prednisolone Cmax  11% Prednisolone AUC0-∞  34%
Danish: Prednisolon Cmax ↑ 11% Prednisolon AUC0-∞ ↑ 34%
English: • Indinavir and other HIV protease inhibitors (used for treating HIV)
Danish: • Indinavir og andre HIV-proteasehæmmere (medicin mod hiv)
English: Breast-feeding must be stopped on initiation of treatment with Voriconazole Accord.
Danish: Amning skal ophøre ved initiering af behandling med Voriconazole Accord.
English: If Voriconazole Accord is continued, however, dermatologic evaluation should be performed on a systematic and regular basis, to allow early detection and management of premalignant lesions.
Danish: Hvis behandling med Voriconazole Accord fortsættes på trods af forekomsten af fototoksicitetsrelaterede læsioner, bør der udføres systematisk og regelmæssig dermatologisk evaluering med henblik på tidlig påvisning og behandling af præmaligne læsioner.
English: After IV voriconazole therapy, the median duration of oral voriconazole therapy was 76 days (range 2232days).
Danish: Efter i.v.-voriconazolbehandling var den mediane varighed af oral voriconazolbehandling 76 dage (interval 2-232 dage).
English: In the pre- and post-natal development study in rats at exposures lower than those obtained in humans with therapeutic doses, voriconazole prolonged the duration of gestation and labour and produced dystocia with consequent maternal mortality and reduced perinatal survival of pups.
Danish: I undersøgelser af den præ- og postnatale udvikling hos rotter, forlængede voriconazol, ved en mindre optagelse end den, der ses ved terapeutiske doser hos mennesker, gestations- og fødselsvarigheden, medførte dystoci med heraf følgende maternal mortalitet, og reducerede den perinatale overlevelse af afkommet.
English: When initiating voriconazole in patients already on tacrolimus, it is recommended that the tacrolimus dose be reduced to a third of the original dose and tacrolimus level carefully monitored.
Danish: Når voriconazol-behandling startes hos patienter, der allerede får tacrolimus anbefales det, at tacrolimus-dosis reduceres til en tredjedel af det oprindelige og tacrolimus-koncentrationerne monitoreres nøje.
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS Blister (Blister foil for 50 mg film-coated tablets (all blister packs))
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS Blister (blisterfolie for 50 mg filmovertrukne tabletter (alle blisterpakninger))
English: Patients receiving Voriconazole Accord must be carefully monitored for hepatic toxicity.
Danish: Patienter, der behandles med voriconazol , skal monitoreres nøje for levertoksicitet.
English: Repeated-dose toxicity studies with voriconazole indicated the liver to be the target organ.
Danish: Forsøg vedrørende toksicitet efter gentagne doser voriconazol tyder på, at leveren er målorganet.
English: Frequent monitoring for adverse reactions and toxicity related to NSAIDs is recommended.
Danish: Hyppig monitorering for NSAIDrelaterede bivirkninger og toksicitet anbefales.
English: The medicines in the following list must not be taken during your course of Voriconazole Accord treatment:
Danish: Følgende typer medicin må ikke indtages under behandlingen med Voriconazole Accord:
English: No dose adjustment is necessary for elderly patients (see section 5.2).
Danish: Dosisjustering er ikke nødvendig hos ældre patienter (se pkt.
English: While being treated with Voriconazole Accord:
Danish: Mens De er i behandling med Voriconazole Accord:
English: Carbamazepine and longacting barbiturates (e.g., phenobarbital, mephobarbital)
Danish: Carbamazepin og langtidsvirkende benzodiazepiner (f.eks. phenobarbital, mephobarbital)
English: In an oral multiple-dose study Cmax and AUCτ in healthy elderly males (≥65 years) were 61% and 86 % higher, respectively, than in healthy young males (18-45 years).
Danish: I et oralt flerdosisstudie med raske, ældre mænd ( 65 år) var Cmax og AUCτ henholdsvis 61% og 86% højere end hos raske, unge mænd (18-45 år).
English: Fentanyl AUC0-∞  1.34-fold
Danish: Fentanyl AUC0-∞ ↑ 1,34 gange
English: If a patient develops a rash they should be monitored closely and Voriconazole Accord discontinued if lesions progress.
Danish: Hvis en patient udvikler udslæt, bør de monitoreres nøje, og Voriconazole Accord afbrydes, hvis læsionen progredierer.
English: The findings of the effect of efavirenz on voriconazole suggest that the metabolism of voriconazole may be induced by an NNRTI
Danish: Resultaterne fra efavirenz' virkning på voriconazol tyder på at metaboliseringen af voriconazol kan blive induceret af NNRTI.
English: Cimetidine (400 mg BID)
Danish: Cimetidin (400 mg BID)
English: For patients less than 40 kg the oral dose may be increased to 150 mg twice daily.
Danish: Hos patienter med en legemsvægt under 40 kg bør den orale dosis øges til 150 mg 2 gange dagligt.
English: Tell your doctor if you are taking the following medicine, as treatment with Voriconazole Accord at the same time should be avoided if possible:
Danish: Fortæl det til lægen, hvis De tager følgende medicin, da behandling samtidig med Voriconazole Accord bør undgås, hvis det er muligt:
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS Blister (Blister foil for 200 mg film-coated tablets (all blister packs))
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS Blister (blisterfolie for 200 mg filmovertrukne tabletter (alle blisterpakninger))
English: Reminds HCPs of use of the HCP Checklist and the Patient Alert Card and how to obtain additional copies.
Danish: - Påminde læger og sundhedspersonale om, at de skal benytte tjeklisten til læger og sundhedspersonale og patientadvarselskortet, samt oplyse om hvordan de kan skaffe flere eksemplarer.
English: As Voriconazole Accord has been known to affect the liver and the kidney, your doctor should monitor the function of your liver and kidney by doing blood tests.
Danish: Da Voriconazole Accord påvirker lever og nyrer, vil Deres læge tage blodprøver for at kontrollere lever- og nyrefunktionen.
English: Voriconazole Accord is intended for patients with worsening, possibly life-threatening, fungal infections.
Danish: Voriconazole Accord er beregnet til patienter med forværrede og potentielt livstruende svampeinfektioner.
English: Voriconazole Accord should be administered primarily to patients with progressive, possibly lifethreatening infections.
Danish: Voriconazole Accord bør fortrinsvis gives til patienter med fremadskridende, muligt livstruende infektioner.
English: Methadone (32-100 mg QD)
Danish: Methadon (32-100 mg QD)
English: Long-Acting Opiates
Danish: Langtidsvirkende opioider
English: Long term exposure (treatment or prophylaxis) greater than 180 days (6 months) requires careful assessment of the benefit-risk balance and physicians should therefore consider the need to limit the exposure to Voriconazole Accord (see sections 4.2 and 5.1).
Danish: Langtidseksponering (behandling eller profylakse) i mere end 180 dage (6 måneder) kræver nøje vurdering af benefit/risk-forholdet, og lægen bør derfor overveje at begrænse eksponeringen for Voriconazole Accord (se pkt.
English: There have been post-marketing reports of prolonged visual adverse events (see section 4.4).
Danish: Der er efter markedsføringen rapporteret om langvarige synsrelaterede bivirkninger (se pkt.
English: When Voriconazole Accord treatment is stopped by your doctor you should not experience any effects.
Danish: Når Deres læge stopper Voriconazole Accord-behandlingen, bør De ikke kunne mærke det.
English: • Squamous cell carcinoma of the skin (SCC)
Danish: • Planocellulært karcinom i huden (SCC)
English: Depending on your response to treatment, your doctor may increase or decrease the daily dose.
Danish: Afhængigt af hvordan behandlingen virker, vil lægen måske øge dosis.
English: Sulfonylureas (e.g., tolbutamide, glipizide, glyburide)
Danish: Sulfonylurinstof (f.eks. tolbutamid, glipizid, glyburid)
English: Very common: may affect more than 1 in 10 people
Danish: Meget almindelige: Kan forekomme hos flere end 1 ud af 10 patienter
English: Dose reduction of sulfonylureas should be considered
Danish: Dosisreduktion af sulfonylurinstof bør overvejes.
English: 2 film-coated tablets 10 film-coated tablets 14 film-coated tablets 20 film-coated tablets 28 film-coated tablets 30 film-coated tablets 50 film-coated tablets 56 film-coated tablets 100 film-coated tablets 10x1 film-coated tablets 14x1 film-coated tablets 28x1 film-coated tablets 30x1 film-coated tablets 56x1 film-coated tablets 100x1 film-coated tablets
Danish: 2 filmovertrukne tabletter 10 filmovertrukne tabletter 14 filmovertrukne tabletter 20 filmovertrukne tabletter 28 filmovertrukne tabletter 30 filmovertrukne tabletter 50 filmovertrukne tabletter 56 filmovertrukne tabletter 100 filmovertrukne tabletter 10 x 1 filmovertrukne tabletter 14 x 1 filmovertrukne tabletter 28 x 1 filmovertrukne tabletter 30 x 1 filmovertrukne tabletter 56 x 1 filmovertrukne tabletter 100 x 1 filmovertrukne tabletter
English: In vitro activity against clinical isolates has been observed for Acremonium spp., Alternaria spp.,
Danish: In vitro aktivitet over for kliniske isolater er set over for Acremonium spp., Alternaria spp., Bipolaris spp., Cladophialophora spp.
English: When initiating voriconazole in patients already on ciclosporin it is recommended that the ciclosporin dose be halved and ciclosporin level carefully monitored.
Danish: Når voriconazol-behandling startes hos patienter, der allerede får ciclosporin anbefales det, at ciclosporin-dosis halveres og ciclosporin-koncentrationerne monitoreres nøje.
English: Interaction Geometric mean changes
Danish: Interaktion Geometrisk gennemsnitlig ændring (%)
English: [CYP450 inducer; P-gp inducer]
Danish: [CYP450 induktor; P-gp induktor]
English: PVC / Aluminium blister in cartons of 2, 10, 14, 20, 28, 30, 50, 56 or 100 film-coated tablets or unit dose PVC / Aluminium blister in pack sizes of 10x1, 14x1, 28x1, 30x1, 56x1 or 100x1 film-coated tablets.
Danish: PVC/aluminiumblister i kartoner med 2, 10, 14, 20, 28, 30, 50, 56 eller 100 filmovertrukne tabletter eller enhedsdosis-PVC/aluminiumblister i pakningsstørrelser med 10 x 1, 14 x 1, 28 x 1, 30 x 1, 56 x 1 eller 100 x 1 filmovertrukne tabletter.
English: Use of standard doses of voriconazole with efavirenz doses of 400 mg QD or higher is contraindicated (see section 4.3).
Danish: Brug af standarddoser af voriconazol med efavirenz-doser på 400 mg QD eller derover er kontraindiceret (se pkt.
English: Oxycodone Cmax  1.7-fold Oxycodone AUC0-∞  3.6-fold
Danish: Oxycodon Cmax ↑ 1,7 gange Oxycodon AUC0-∞ ↑ 3,6 gange
English: Squamous cell carcinoma of the skin (SCC) has been reported in relation with long-term Voriconazole Accord treatment.
Danish: Planocellulært karcinom i huden (SCC) er blevet rapporeret i forbindelse med langtidbehandling med Voriconazole Accord.
English: Accord Healthcare Limited, Sage House, 319 Pinner Road, North Harrow, Middlesex, HA1 4HF, United Kingdom
Danish: Accord Healthcare Limited, Sage House, 319 Pinner Road, North Harrow,
English: If the liver function tests become markedly elevated, Voriconazole Accord should be discontinued, unless the medical judgment of the risk-benefit of the treatment for the patient justifies continued use.
Danish: Hvis leverfunktionsværdierne forhøjes mærkbart, bør voriconazol seponeres, medmindre fortsat anvendelse kan forsvares på grundlag af en medicinsk vurdering af risk-benefit-forholdet for patienten.
English: Voriconazole is a triazole antifungal agent.
Danish: Voriconazol er et antimykotika af triazolgruppen.
English: Statins (e.g., lovastatin)
Danish: Statiner (f.eks. lovastatin)
English: EU/1/13/835/010 2 film-coated tablets EU/1/13/835/011 10 film-coated tablets EU/1/13/835/012 14 film-coated tablets EU/1/13/835/013 20 film-coated tablets EU/1/13/835/014 28 film-coated tablets EU/1/13/835/015 30 film-coated tablets EU/1/13/835/016 50 film-coated tablets EU/1/13/835/017 56 film-coated tablets EU/1/13/835/018 100 film-coated tablets EU/1/13/835/025 10x1 film-coated tablets EU/1/13/835/026 14x1 film-coated tablets EU/1/13/835/027 28x1 film-coated tablets EU/1/13/835/028 30x1 film-coated tablets EU/1/13/835/029 56x1 film-coated tablets EU/1/13/835/030 100x1 film-coated tablets
Danish: EU/1/13/835/010 2 filmovertrukne tabletter EU/1/13/835/011 10 filmovertrukne tabletter EU/1/13/835/012 14 filmovertrukne tabletter EU/1/13/835/013 20 filmovertrukne tabletter EU/1/13/835/014 28 filmovertrukne tabletter EU/1/13/835/015 30 filmovertrukne tabletter EU/1/13/835/016 50 filmovertrukne tabletter EU/1/13/835/017 56 filmovertrukne tabletter EU/1/13/835/018 100 filmovertrukne tabletter EU/1/13/835/025 10 x 1 filmovertrukne tabletter EU/1/13/835/026 14 x 1 filmovertrukne tabletter EU/1/13/835/027 28 x 1 filmovertrukne tabletter EU/1/13/835/028 30 x 1 filmovertrukne tabletter EU/1/13/835/029 56 x 1 filmovertrukne tabletter EU/1/13/835/030 100 x 1 filmovertrukne tabletter
English: Patients have developed severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) (uncommon), toxic epidermal necrolysis (TEN) (rare), drug reaction with eosinophilia and systemic symptoms (DRESS) (rare) and erythema multiforme (rare) during treatment with voriconazole (see section 4.4).
Danish: Patienterne har udviklet svære kutane bivirkninger (SCAR), herunder Stevens-Johnsons syndrom (SJS) (ikke almindelig), toksisk epidermal nekrolyse (TEN) (sjælden) og erythema multiforme (sjælden) under behandling med voriconazol (se pkt.
English: Prednisolone (60 mg single dose)
Danish: Prednisolon (60 mg enkeltdosis)
English: 3 In clinical studies, response to voriconazole in C. krusei infections was similar to C. albicans, C. parapsilosis and C. tropicalis.
Danish: 3 I kliniske forsøg svarede responset på voriconazol hos patienter med infektion med C. krusei til responset ved C. albicans, C. parapsilosis og C. tropicalis.
English: includingT.
Danish: justeres.
English: Do not take Voriconazole Accord If you are allergic to voriconazole or any of the other ingredients of this medicine (listed in section 6).
Danish: Hvis De er overfølsom (allergisk) over for voriconazol eller et af de øvrige indholdsstoffer (angivet i punkt 6).
English: Caution should be used in prescribing Voriconazole Accord to patients with hypersensitivity to other azoles (see also section 4.8).
Danish: Forsigtighed tilrådes, når Voriconazole Accord gives til patienter, der er overfølsomme over for andre azoler (se også pkt.
English: Transcriptase Inhibitors (NNRTIs) (e.g., delavirdine, nevirapine)*
Danish: Andre non-nucleosid reverse transcriptase-hæmmer (NNRTI) (f.eks. delavirdin, nevirapin)*
English: If patient response to treatment is inadequate, the dose may be increased by 1 mg/kg steps (or by 50 mg steps if the maximum oral dose of 350 mg was used initially).
Danish: Ved utilstrækkeligt behandlingsrespons kan dosis øges i trin på 1 mg/kg (eller 50 mg/trin, hvis den maksimale orale dosis på 350 mg blev anvendt initialt).