FrancophonIA/ELRC3.0 huggingface dataset:
English: For the full list of side effects and restrictions with Ultomiris, see the package leaflet.
Croatian: Potpuni popis nuspojava i ograničenja lijeka Ultomiris potražite u uputi o lijeku.
English: How is Ultomiris used?
Croatian: Kako se Ultomiris primjenjuje?
English: Ultomiris contains the active substance ravulizumab.
Croatian: Ultomiris sadrži djelatnu tvar ravulizumab.
English: Adults and elderly (> 65 years)
Croatian: Odrasli i starije osobe (> 65 godina)
English: Please tell your doctor immediately:
Croatian: Odmah obavijestite liječnika:
English: Other pharmaceutical forms may be available for this population.
Croatian: Drugi farmaceutski oblici mogu biti dostupni za tu populaciju.
English: The volume of distribution is high (approximately 1,000 litres), indicating extensive distribution.
Croatian: Volumen distribucije je velik (oko 1000 litara), što ukazuje na široku distribuciju.
English: The risk of having seizures is higher if you have had them before;
Croatian: Rizik pojave napadaja veći je ako ste ih već doživjeli;
English: Tell your doctor if you are taking the following medicines.
Croatian: Obavijestite svojeg liječnika o tome uzimate li sljedeće lijekove.
English: The major circulating metabolites are inactive.
Croatian: Najvažniji cirkulirajući metaboliti su neaktivni.
English: A population pharmacokinetic analysis was performed to evaluate the effects of demographic characteristics.
Croatian: Farmakokinetička analiza populacije je provedena za procjenu učinaka demografskih karakteristika.
English: For additional information see section 4.
Croatian: Za dodatne informacije, pročitajte dio 4.
English: 117 Allee des Parcs 69 800 Saint Priest France
Croatian: 117 Allee des Parcs 69 800 Saint Priest Francuska
English: No change in starting dose is necessary.
Croatian: Nije potrebna prilagodba početne doze.
English: McDermott Laboratories Limited trading as Gerard Laboratories 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Ireland
Croatian: McDermott Laboratories Limited koji posluje pod nazivom Gerard Laboratories 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13 Irska
English: Hypotension and/or worsening heart failure
Croatian: Hipotenzija i/ili pogoršanje zatajenja srca
English: Cinacalcet is approximately 97% bound to plasma proteins and distributes minimally into red blood cells.
Croatian: Sinakalcet je oko 97 % vezan za proteine plazme i minimalno se distribuira u crvene krvne stanice.
English: Hypocalcaemia (see sections 4.2 and 4.4).
Croatian: Hipokalcemija (vidjeti dijelove 4.2 i 4.4).
English: Very common: may affect more than 1 in 10 people • nausea and vomiting, these side effects are normally quite mild and do not last for long.
Croatian: Vrlo često: mogu se javiti u više od 1 na 10 osoba • mučnina i povraćanje; ove nuspojave su uglavnom blage i ne traju dugo.
English: Animal studies do not indicate direct harmful effects with respect to pregnancy, parturition or postnatal development.
Croatian: Ispitivanja na životinjama nisu ukazala na izravne štetne učinke na trudnoću, porođaj ili postnatalni razvoj.
English: Treatment should be reinitiated using the next lowest dose of cinacalcet.
Croatian: Liječenje treba ponovno započeti primjenjujući sljedeću najnižu dozu cinakalceta.
English: Your doctor will take regular blood samples during treatment to monitor your progress and will adjust your dose if necessary.
Croatian: Vaš liječnik redovito će vam vaditi krv tijekom lječenja kako bi pratio Vaš napredak i po potrebi prilagodio dozu lijeka.
English: Clearance of cinacalcet may be lower in women than in men.
Croatian: Klirens cinakalceta može biti manji u žena nego u muškaraca.
English: The clinical significance of these reductions in serum testosterone is unknown.
Croatian: Klinički značaj ovih smanjenja serumskog testosterona nije poznat.
English: Children under the age of 18 must not take Cinacalcet Mylan.
Croatian: Djeca i adolescenti Djeca mlađa od 18 godina ne smiju uzimati Cinacalcet Mylan.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines particularly etelcalcetide or any other medicines that lower the level of calcium in your blood.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove, osobito etelkalcetid ili bilo koje druge lijekove koji snižavaju vrijednost kalcija u krvi.
English: Cinacalcet did not show any genotoxic or carcinogenic potential.
Croatian: Sinakalcet nije pokazao genotoksični ili karcinogeni potencijal.
English: • loss (anorexia) or decrease of appetite
Croatian: • gubitak (anoreksija) ili smanjenje apetita
English: You should inform your doctor if you experience any of the signs of low calcium levels as described above.
Croatian: Obratite se svom liječniku ako uočite bilo koji od znakova niske vrijednosti kalcija opisanih ranije.
English: Approximately 80% of the dose was recovered in the urine and 15% in the faeces.
Croatian: Oko 80 % doze otkriveno je u urinu i 15 % u stolici.
English: Before you start taking Cinacalcet Mylan, tell your doctor if you have or have ever had:
Croatian: Prije nego što počnete uzimati Cinacalcet Mylan,obavijestite svojeg liječnika o tome imate li ili ste bilo kada imali:
English: There were no effects on fertility in animal studies.
Croatian: Nije bilo utjecaja na plodnost u ispitivanjima na životinjama.
English: Talk to your doctor, pharmacist or nurse before taking Cinacalcet Mylan.
Croatian: Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego uzmete Cinacalcet Mylan.
English: Do not take Cinacalcet Mylan if you are allergic to cinacalcet or any of the other ingredients of this medicine (listed in section 6).
Croatian: Nemojte uzimati Cinacalcet Mylan ako ste alergični na sinakalcet ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: The clinical relevance is unknown, however, the potential for cinacalcet to act on these secondary targets cannot be fully excluded.
Croatian: Klinički značaj nije poznat, ali mogućnost da sinakalcet djeluje na te sekundarne ciljeve ne može se potpuno isključiti.
English: In the event of overdose, patients should be monitored for signs and symptoms of hypocalcaemia, and treatment should be symptomatic and supportive.
Croatian: U slučaju predoziranja, bolesnike se mora nadzirati zbog znakova i simptoma hipokalcemije a liječenje mora biti simptomatsko i potporno.
English: After adjusting for baseline characteristics in a secondary analysis, the HR for the primary composite endpoint was 0.88; 95% CI: 0.79, 0.97.
Croatian: Nakon prilagodbe za početne značajke u sekundarnoj analizi, HR za primarni kompozitni ishod iznosio je 0,88; 95% CI: 0,79, 0,97.
English: LABEL (BOTTLES)
Croatian: NALJEPNICA (BOCE)
English: At doses above 200 mg, the absorption was saturated probably due to poor solubility.
Croatian: Pri dozama iznad 200 mg apsorpcija je zasićena, najvjerojatnije zbog loše topivosti.
English: Do not take Cinacalcet Mylan if you have low levels of calcium in your blood.
Croatian: Nemojte uzimati Cinacalcet Mylan ako imate niske vrijednosti kalcija u krvi.
English: * see section c) see section 4.4
Croatian: *vidjeti dio c) vidjeti dio 4.4
English: Your doctor will tell you how much Cinacalcet Mylan you must take.
Croatian: Vaš liječnik će vam reći koliko lijeka Cinacalcet Mylan morate uzeti.
English: Cinacalcet Mylan should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
Croatian: Cinacalcet Mylan smije se primjenjivati tijekom trudnoće samo ako moguća korist nadmašuje mogući rizik za fetus.
English: In pregnant rats, there were slight decreases in body weight and food consumption at the highest dose.
Croatian: U skotnih štakora došlo je do lagana smanjenja tjelesne težine i potrošnje hrane pri najvećoj dozi.
English: Nausea and vomiting were mild to moderate in severity and transient in nature in the majority of patients.
Croatian: Mučnina i povraćanje bile su blage do umjerene težine i prolazne naravi u većine bolesnika.
English: Low calcium levels can have an effect on your heart rhythm.
Croatian: Niske razine kalcija mogu utjecati na srčani ritam.
English: Increases in plasma cinacalcet concentration are similar, regardless of the fat content of the meal.
Croatian: Povećanje koncentracije cinakalcet u plazmi slično je bez obzira na količinu masti u obroku.
English: • a medicine used to treat HIV infection and AIDS (ritonavir)
Croatian: • lijek koji se koristi za liječenje HIV infekcija i AIDS (ritonavir)
English: If a patient stops or starts smoking, cinacalcet plasma levels may change and dose adjustment may be necessary.
Croatian: Ako bolesnik prestane ili počne pušiti, može se promijeniti razina cinakalceat u plazmi i možda će biti potrebno prilagoditi dozu.
English: An open-label extension of this study showed no further reductions in free and total testosterone concentrations over a period of 3 years in cinacalcet-treated patients.
Croatian: Otvoreni nastavak ovog ispitivanja nije pokazao daljnje sniženje koncentracije slobodnog i ukupnog testosterona u bolesnika liječenih cinakalcetom u razdoblju od 3 godine.
English: After taking cinacalcet a very small number of patients with heart failure had worsening of their condition and/or low blood pressure (hypotension).
Croatian: Nakon uzimanja Cinakalceta Mylan vrlo mali broj bolesnika sa zatajenjem srca doživio je pogoršanje stanja i/ili niski krvni tlak (hipotenziju).
English: Adverse reactions, considered at least possibly attributable to cinacalcet treatment in the placebo controlled studies and single-arm studies based on best-evidence assessment of causality are listed below using the following convention: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000); not known (cannot be estimated from the available data).
Croatian: Nuspojave, za koje se smatra da postoji barem mogućnost da se mogu pripisati liječenju sinakalcetom u placebom kontroliranim ispitivanjima i ispitivanjima na jednoj skupini prema procjeni uzročnoposljedične veze na temelju najboljih dokaza navedene su niže prema sljedećoj konvenciji: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000); nepoznato (ne može se procijeniti iz dostupnih podataka).
English: If you forget to take Cinacalcet Mylan Do not take a double dose to make up for a forgotten dose.
Croatian: Ako ste zaboravili uzeti lijeka Cinacalcet Mylan Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: The frequencies of the individual preferred terms including angioedema and urticaria cannot be estimated from available data.
Croatian: Učestalosti pojedinih preporučenih izraza uključujući angioedem i urtikariju ne mogu se procijeniti iz dostupnih podataka.
English: Cinacalcet Mylan is used:
Croatian: Cinacalcet Mylan se koristi:
English: This analysis showed no significant impact of age, sex, race, body surface area, and body weight on cinacalcet pharmacokinetics.
Croatian: Ova analiza je pokazala da ne postoji značajan utjecaj dobi, spola, rase, tjelesne površine i tjelesne težine na farmakokinetiku cinakalceta.cinakalcetacinakalceta
English: Smoking induces CYP1A2; the clearance of cinacalcet was observed to be 36-38% higher in smokers than non-smokers.
Croatian: Pušenje inducira CYP1A2; opažen je 36 % do 38 % veći klirens cinakalceta kod pušača u odnosu na nepušače.
English: Safety margins from the toxicology studies are small due to the dose-limiting hypocalcaemia observed in the animal models.
Croatian: Sigurnosne granice u toksikološkim ispitivanjima su male zbog zapažene hipokalcemije koja je ograničavala dozu na životinjskim modelima.
English: In case of pregnancy, your doctor may decide to modify your treatment, as cinacalcet might harm the unborn baby.
Croatian: U slučaju trudnoće, vaš liječnik može promijeniti terapiju jer sinakalcet može biti štetan za vaše nerođeno dijete.
English: Tell your doctor if you experience an unusually fast or pounding heartbeat, if you have heart rhythm problems, or if you take medicines known to cause heart rhythm problems, while taking Cinacalcet Mylan.
Croatian: Obavijestite svog liječnika ako osjetite neobično ubrzano ili jako lupanje srca, ako imate tegobe sa srčanim ritmom ili ako uzimate lijekove za koje se zna da uzrokuju tegobe sa srčanim ritmom, dok uzimate Cinacalcet Mylan.
English: It is important that you take your dose of Cinacalcet Mylan as advised by your doctor.
Croatian: Važno je da uzmete dozu Cinakalceta Mylan koju Vam je preporučio Vaš liječnik.
English: The normal calcium range may differ depending on the methods used by your local laboratory.
Croatian: Granice referentnih vrijednosti kalcija mogu se razlikovati ovisno o metodama kojima se koristi lokalni laboratorij.
English: You should not take Cinacalcet Mylan together with etelcalcetide.
Croatian: Ne smijete uzimati Cinakalcet Mylan zajedno s etelkalcetidom.
English: The pharmacokinetics of cinacalcet does not change over time.
Croatian: Farmakokinetika cinakalceta s vremenom se ne mijenja.
English: It is recommended that Cinacalcet Mylan be taken with food or shortly after a meal, as studies have shown that bioavailability of cinacalcet is increased when taken with food (see section 5.2).
Croatian: Preporučuje se Cinacalcet Mylan uzeti s hranom ili neposredno nakon obroka jer su ispitivanja pokazala kako je bioraspoloživost cinakalceta povećana kad se uzima s hranom (vidjeti dio 5.2).
English: The study did not meet its primary objective of demonstrating a reduction in risk of all-cause mortality or cardiovascular events including myocardial infarction, hospitalisation for unstable angina, heart failure or peripheral vascular event (HR 0.93; 95% CI: 0.85, 1.02; p = 0.112).
Croatian: Ispitivanje nije postiglo primarni cilj da pokaže smanjenje rizika od mortaliteta svih uzroka ili kardiovaskularnih događaja uključujući infarkt miokarda, hospitalizaciju zbog nestabilne angine, zatajenje srca ili periferni krvožilni događaj (HR 0,93; 95% CI: 0,85, 1,02; p = 0,112).
English: • allergic reactions (hypersensitivity)
Croatian: • alergijske reakcije (preosjetljivost)
English: OUTER CARTON (BLISTERS AND BOTTLES)
Croatian: KUTIJA (BLISTERI I BOCE)
English: After administration of a 75 mg radiolabelled dose to healthy volunteers, cinacalcet was rapidly and extensively metabolised by oxidation followed by conjugation.
Croatian: Nakon primjene radioaktivno obilježene doze od 75 mg zdravim dobrovoljcima, sinakalcet se brzo i ekstenzivno metabolizira oksidacijom, a nakon toga konjugacijom.
English: Your doctor will monitor your blood calcium levels.
Croatian: Vaš liječnik će kontrolirati vrijednost kalcija u krvi.
English: Reductions in iPTH and Ca x P were maintained for up to 12 months of treatment.
Croatian: Sniženje iPTH-a i Ca x P održavalo se tijekom 12 mjeseci liječenja.
English: Do not use this medicine after the expiry date which is stated on the blister, carton or bottle after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na blisteru, kutiji ili boci iza oznake EXP.
English: The safety and efficacy of cinacalcet in the paediatric population have not been established.
Croatian: Sigurnost i djelotvornost cinakalceta u pedijatrijskoj populaciji nisu ustanovljeni.
English: Renal insufficiency
Croatian: Renalna insuficijencija
English: All of these effects were seen at a systemic exposure, on an AUC basis, approximately equivalent to the exposure in patients at the maximum dose for secondary HPT.
Croatian: Svi navedeni učinci zabilježeni su kod sistemske izloženosti, na temelju AUC, približno ekvivalentne izloženosti u bolesnika kod maksimalne doze za sekundarni HPT.
English: The maximum dose used in clinical trials was 90 mg four times daily.
Croatian: Maksimalna doza upotrijebljena u kliničkim ispitivanjima bila je 90 mg četiri puta dnevno.
English: Adynamic bone disease may develop if PTH levels are chronically suppressed below approximately 1.5 times the upper limit of normal with the iPTH assay.
Croatian: Adinamična koštana bolest može nastati ako je vrijednost PTH-a kronično suprimirana ispod otprilike 1,5 puta gornje granice normale za iPTH test.
English: Demographic and baseline characteristics were representative of the dialysis patient population with secondary HPT.
Croatian: Demografske i početne karakteristike bile su reprezentativne za populaciju dijaliziranih bolesnika sa sekundarnim HPT-om.
English: Cinacalcet Mylan contains the active ingredient cinacalcet, which works by controlling the levels of parathyroid hormone (PTH), calcium and phosphorous in your body.
Croatian: Cinacalcet Mylan sadrži djelatnu tvar sinakalcet koja djeluje kontroliranjem razine paratiroidnog hormona (PTH), kalcija i fosfora u vašem tijelu.
English: After single and multiple once daily oral doses of cinacalcet, plasma cinacalcet concentrations (Cmax and AUC values after normalisation by dose and weight) were similar to those observed in adult patients.
Croatian: Nakon jednokratne i višekratnih peroralnih dnevnih doza cinakalceta, koncentracije cinakalceta u plazmi (Cmax i AUC vrijednosti nakon normalizacije prema dozi i tjelesnoj težini) bile su slične onima zabilježenim u odraslih bolesnika.
English: The effect of CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin) on cinacalcet plasma levels has not been studied.
Croatian: Učinak inhibitora CYP1A2 (npr. fluvoksamin, ciprofloksacin) na razine cinakalceta u plazmi nije ispitan.
English: Dose adjustment may be necessary if a patient starts or stops smoking or when concomitant treatment with strong CYP1A2 inhibitors is initiated or discontinued.
Croatian: Možda će biti potrebna prilagodba doze lijeka ako bolesnik počne ili prestane pušiti, ili ako počne ili prekine istodobno liječenje snažnim inhibitorima CYP1A2.
English: What Cinacalcet Mylan is and what it is used for What you need to know before you take Cinacalcet Mylan How to take Cinacalcet Mylan Possible side effects
Croatian: Što je Cinacalcet Mylan i za što se koristi Što morate znati prije nego počnete uzimati Cinacalcet Mylan Kako uzimati Cinacalcet Mylan Moguće nuspojave
English: The safety and efficacy of cinacalcet in children for the treatment of parathyroid carcinoma and primary hyperparathyroidism have not been established.
Croatian: Sigurnost i djelotvornost cinakalceta u djece za liječenje paratireoidnog karcinoma i primarnog hiperparatireoidizma nisu ustanovljene.
English: The tablets must be taken whole and are not to be chewed, crushed or divided.
Croatian: Tablete se moraju uzeti cijele i ne smiju se žvakati, drobiti ili lomiti.
English: The primary endpoint of the study was a reduction of serum calcium of ≥ 1 mg/dl (≥ 0.25 mmol/l).
Croatian: Mjera primarnog ishoda ispitivanja bila je smanjenje serumskog kalcija za ≥ 1 mg/dl (≥ 0,25 mmol/l).
English: • primary HPT for whom parathyroidectomy would be indicated on the basis of serum calcium levels (as defined by relevant treatment guidelines), but in whom parathyroidectomy is not clinically appropriate or is contraindicated.
Croatian: • primarnim HPT-om, kojima je indicirana paratireoidektomija na osnovi vrijednosti serumskog kalcija (kao što je definirano relevantnim terapijskim smjernicama), ali kojima paratireoidektomija nije klinički odgovarajuća ili je kontraindicirana.
English: Recommendations
Croatian: Preporuke
English: Cinacalcet Mylan may be used as part of a therapeutic regimen including phosphate binders and/or vitamin D sterols, as appropriate (see section 5.1).
Croatian: Cinacalcet Mylan može biti dio terapijskog režima koji uključuje tvari koje vežu fosfate i/ili vitamin D, kao što je preporučeno (vidjeti dio 5.1).
English: Effect of cinacalcet on other medicines
Croatian: Učinak cinakalceta na druge lijekove
English: After absorption, cinacalcet concentrations decline in a biphasic fashion with an initial half-life of approximately 6 hours and a terminal half-life of 30 to 40 hours.
Croatian: Nakon apsorpcije, koncentracije cinakalceta smanjuju se na bifazičan način s početnim poluvijekom od oko 6 sati i terminalnim poluvijekom od 30 do 40 sati.
English: Discontinuation of therapy as a result of undesirable effects was mainly due to nausea and vomiting.
Croatian: Prekid terapije zbog nuspojava uglavnom je učinjen zbog mučnine i povraćanja.
English: 66% of patients were receiving vitamin D sterols at study entry, and > 90% were receiving phosphate binders.
Croatian: Na početku ispitivanja 66 % bolesnika primalo je sterole vitamina D, a > 90 % bolesnika primalo je tvari koje vežu fosfate.
English: What you need to know before you take Cinacalcet Mylan
Croatian: Što morate znati prije nego počnete uzimati Cinacalcet Mylan
English: There were no effects on fertility in males or females at exposures up to 4 times a human dose of 180 mg/day (safety margins in the small population of patients administered a maximum clinical dose of 360 mg daily would be approximately half those given above).
Croatian: Nije bilo učinaka na plodnost u štakora ženskog i muškog spola izloženih dozi 4 puta većoj od humane doze od 180 mg/dnevno (sigurnosne granice u maloj grupi bolesnika koji su primali maksimalnu kliničku dozu od 360 mg dnevno bile bi otprilike polovica od gore navedenih).
English: If you are being treated for secondary hyperparathyroidism, your doctor should monitor your calcium levels before starting treatment with Cinacalcet Mylan and during treatment with Cinacalcet Mylan.
Croatian: Ako Vam je potrebno liječenje za sekundarni hiperparatireoidizam, Vaš bi liječnik trebao kontrolirati vrijednosti kalcija prije početka liječenja Cinakalcetom Mylan i za vrijeme liječenja Cinakalcetom Mylan.
English: Cinacalcet Mylan with food and drink Cinacalcet Mylan should be taken with or shortly after food.
Croatian: Cinacalcet Mylan s hranom i pićem Cinacalcet Mylan treba uzeti s hranom ili neposredno nakon obroka.
English: • Unusually fast or pounding heart beat which may be associated with low levels of calcium in your blood (QT prolongation and ventricular arrhythmia secondary to hypocalcaemia).
Croatian: • neobično ubrzano ili jako lupanje srca, koje može biti povezano s niskim razinama kalcija u krvi (produljenje QT intervala i ventrikularna aritmija uzrokovana hipokalcemijom).
English: Caution is advised in patients with other risk factors for QT prolongation such as patients with known congenital long QT syndrome or patients receiving medicinal products known to cause QT prolongation.
Croatian: Savjetuje se oprez u bolesnika s drugim čimbenicima rizika za produljenje QT intervala, kao što su bolesnici za koje se zna da imaju sindrom produljenog QT intervala ili bolesnici koji primaju lijekove za koje se zna da produljuju QT interval.
English: Clearance of cinacalcet is higher in smokers than in non-smokers, likely due to induction of CYP1A2mediated metabolism.
Croatian: Klirens cinakalceta veći je u pušača nego kod nepušača, najvjerojatnije zbog indukcije metabolizma posredovanog putem CYP1A2.
English: Tablets should be taken whole and should not be chewed, crushed or divided.
Croatian: Tablete treba uzeti cijele, ne smiju se žvakati, drobiti ili lomiti.
English: However, efficacy, safety, optimal doses and treatment targets have not been established in treatment of predialytic renal failure patients.
Croatian: Međutim, djelotvornost, sigurnost i optimalna doza te ciljevi terapije nisu dokazani u liječenju predijaliznih bolesnika sa zatajenjem bubrega.
English: Cataracts and lens opacities were observed in the repeat dose rodent toxicology and carcinogenicity studies, but were not observed in dogs or monkeys or in clinical studies where cataract formation was monitored.
Croatian: Katarakta i opacifikacija leća primijećena je u ispitivanjima toksikologije i karcinogeničnosti s ponovljenim dozama u glodavaca, ali nisu primijećeni u pasa i majmuna ili u kliničkim ispitivanjima gdje je praćena pojava katarakte.
English: Corrected Serum calcium level or clinical symptoms of hypocalcaemia
Croatian: Korigirana vrijednost serumskog kalcija ili klinički simptomi hipokalcemije