FrancophonIA/ELRC3.0 huggingface dataset:
English: Leukocytosis (WBC > 50 x 109/l) was observed in 41% of normal donors and transient thrombocytopenia (platelets < 100 x 109/l) following filgrastim and leukapheresis was observed in 35% of donors (see section 4.4).
Slovenian: Levkocitozo (število levkocitov > 50 x 109/l) so opazili pri 41 % zdravih darovalcev, prehodno trombocitopenijo (število trombocitov < 100 x 109/l) pa so po dajanju filgrastima in levkaferezi ugotovili pri 35 % darovalcev (glejte poglavje 4.4).
English: There is insufficient data to evaluate filgrastim use in geriatric subjects for other approved filgrastim indications.
Slovenian: Za oceno uporabe filgrastima pri geriatričnih osebah za druge odobrene indikacije filgrastima ni dovolj podatkov.
English: Filgrastim may be given as a 24 hour subcutaneous continuous infusion or subcutaneous injection.
Slovenian: Filgrastim je mogoče dajati kot 24-urno neprekinjeno subkutano infuzijo ali kot subkutano injekcijo.
English: Recipients of allogeneic PBPCs mobilised with filgrastim experienced significantly more rapid haematological recovery, leading to a significant decrease in time to unsupported platelet recovery when compared with allogeneic bone marrow transplantation.
Slovenian: Pri prejemnikih alogenskih matičnih celic (PBPC), izplavljenih z uporabo filgrastima, je prišlo do znatno hitrejšega hematološkega okrevanja, kar je imelo za posledico pomembno skrajšanje časa do nepodprte obnove trombocitov v primerjavi z alogensko presaditvijo kostnega mozga.
English: • if you get left upper belly (abdominal) pain, pain below the left rib cage or pain at the tip of your shoulder, as there may be a problem with your spleen [enlargement of the spleen (splenomegaly) or rupture of the spleen].
Slovenian: • če začutite bolečino v zgornjem levem delu trebuha (abdominalna bolečina), bolečino pod levim delom prsnega koša ali bolečino na vrhu rame, ker imate morda težave z vranico [povečanje vranice (splenomegalijo) ali raztrganje vranice].
English: Treatment with filgrastim significantly reduces the duration of febrile neutropenia, antibiotic use and hospitalisation after induction chemotherapy for acute myelogenous leukaemia or myeloablative therapy followed by bone marrow transplantation.
Slovenian: Zdravljenje s filgrastimom znatno zmanjša trajanje febrilne nevtropenije, uporabo antibiotikov in hospitalizacijo po začetku uvedbe kemoterapije akutne mielogene levkemije ali mieloablacijski terapiji, ki ji sledi presaditev kostnega mozga.
English: Filgrastim did not affect reproductive performance or fertility in male or female rats (see section 5.3).
Slovenian: Plodnost Filgrastim ni vplival na plodnost podganjih samcev in samic (glejte poglavje 5.3).
English: Pre-filled syringe (type I glass) with injection needle (stainless steel), with or without a needle safety guard, containing 0.5 ml solution.
Slovenian: Napolnjena injekcijska brizga (steklo tipa I) z injekcijsko iglo (iz nerjavečega jekla), z varnostno zaščito za iglo ali brez nje, ki vsebuje 0,5 ml raztopine.
English: Reversal of neutropenia or maintaining normal neutrophil counts: Filgrastim should be given by subcutaneous injection.
Slovenian: Odpravljanje nevtropenije ali vzdrževanje normalnega števila nevtrofilcev: Filgrastim se daje kot subkutana injekcija.
English: After injecting the liquid, remove the needle while maintaining pressure on the plunger and then let go of your skin.
Slovenian: Po vbrizganju raztopine iglo izvlecite med tem, ko še vedno ohranjate pritisk na bat, nato pa kožo izpustite.
English: Intravenous (80 µg/kg/day) administration of filgrastim to rabbits during the period of organogenesis was maternally toxic and increased spontaneous abortion, post-implantation loss, and decreased mean live litter size and foetal weight were observed.
Slovenian: Pri intravenskem (80 µg/kg/dan) dajanju filgrastima kuncem v obdobju organogeneze so ugotovili toksične učinke na brejo samico in povečane stopnje spontanega abortusa, postimplantacijske izgube ter zmanjšanja povprečne velikosti legla in mase ploda.
English: The symptoms experienced included fever, abdominal pain, malaise, back pain and inflammatory markers (e.g. C-reactive protein and white blood cell count) were raised.
Slovenian: Simptomi, ki so se pojavili, vključujejo povišano telesno temperaturo, bolečine v trebuhu, slabo počutje, bolečine v hrbtu in povišane vrednosti vnetnih označevalcev (npr. C-reaktivnega proteina in števila belih krvnih celic).
English: You should talk to your doctor about your risks of developing cancers of the blood and what testing should be done.
Slovenian: O tveganju za razvoj krvnega raka in testiranjih, ki so potrebna, se pogovorite z zdravnikom.
English: Special precautions in patients with HIV infection
Slovenian: Posebni previdnostni ukrepi pri bolnikih z okužbo s HIV
English: There is insufficient data to further evaluate filgrastim use in paediatric subjects.
Slovenian: Podatkov za dodatno oceno uporabe filgrastima pri pediatričnih bolnikih ni dovolj.
English: Donors who receive G-CSFs for PBPC mobilisation should be monitored until haematological indices return to normal.
Slovenian: Darovalce, ki za izplavljanje matičnih celic v periferno kri dobivajo G-CFS, je treba spremljati, dokler se jim hematološke vrednosti ne normalizirajo.
English: Clear, colourless to slightly yellowish solution.
Slovenian: Bistra, brezbarvna do rahlo rumenkasta raztopina.
English: When a PBPC transplantation is envisaged it is advisable to plan the stem cell mobilisation procedure early in the treatment course of the patient.
Slovenian: Če je predvidena presaditev matičnih celic iz periferne krvi, je postopek izplavljanja matičnih celic priporočljivo načrtovati v zgodnjem obdobju bolnikovega zdravljenja.
English: The median serum elimination half-life (t1/2) of filgrastim after single subcutaneous doses ranged from 2.7 hours (1.0 MU/kg, 10 µg/kg) to 5.7 hours (0.25 MU/kg, 2.5 µg/kg) and was prolonged after 7 days of dosing to 8.5 - 14 hours, respectively.
Slovenian: Mediana razpolovne dobe izločanja iz seruma (t½) filgrastima je znašala od 2,7 ure (1,0 M e./kg, 10 g/kg) do 5,7 ure (0,25 M e./kg, 2,5 g/kg) po enkratnem subkutanem odmerku zdravila, po sedmih dneh dajanja zdravila pa se je podaljšala na 8,5 - 14 ur.
English: Kidney injury has been seen in patients who received filgrastim.
Slovenian: Poškodbo ledvic so opazili pri bolnikih, ki so prejemali filgrastim.
English: If you forget to use Filgrastim HEXAL
Slovenian: Če ste pozabili uporabiti zdravilo Filgrastim HEXAL
English: For reversal of neutropenia The recommended starting dose of filgrastim is 0.1 MU/kg/day (1 μg/kg/day), with titration up to a maximum of 0.4 MU/kg/day (4 μg/kg/day) until a normal neutrophil count is reached and can be maintained (ANC > 2.0 x 109/l).
Slovenian: Priporočeni začetni odmerek filgrastima je 0,1 M e./kg/dan (1 µg/kg/dan), ki se ga daje, s titriranjem do največ 0,4 M e./kg/dan (4 µg/kg/dan), dokler ni doseženo normalno število nevtrofilcev, ki ga je mogoče tudi vzdrževati (absolutno število nevtrofilcev (ANC > 2,0 x 109/l).
English: Filgrastim may be given as a daily subcutaneous injection or as a daily intravenous infusion diluted in 5% glucose solution given over 30 minutes (see section 6.6).
Slovenian: Filgrastim je mogoče dajati kot vsakodnevno subkutano injekcijo ali kot vsakodnevno 30 minutno intravensko infuzijo, razredčeno s 5 % raztopino glukoze (glejte poglavje 6.6).
English: There have been reports of Graft versus Host Disease (GvHD) and fatalities in patients receiving G-CSF after allogeneic bone marrow transplantation (see section 4.8 and 5.1).
Slovenian: Poročali so o reakcijah presadka proti gostitelju (GvHD - Graft versus Host Disease) in o smrtnih primerih pri bolnikih, ki so G-CSF prejemali po alogenski presaditvi kostnega mozga (glejte poglavji 4.8 in 5.1).
English: • to increase the number of white blood cells if you suffer from severe chronic neutropenia to help prevent infections;
Slovenian: • za povečanje števila belih krvnih celic, če imate hudo kronično nevtropenijo, kot pomoč pri preprečevanju okužb;
English: N Acute Grade II - IV GvHD
Slovenian: Akutna reakcija presadka proti gostitelju (GvHD) stopnje II - IV
English: The needle safety guard covers the needle after injection to prevent needle stick injury.
Slovenian: Varnostna zaščita za iglo po injiciranju iglo prekrije, da bi tako preprečila poškodbe zaradi vboda z iglo.
English: - In patients, children or adults, with severe congenital, cyclic, or idiopathic neutropenia with an absolute neutrophil count (ANC) of ≤ 0.5 x 109/l, and a history of severe or recurrent infections, long term administration of filgrastim is indicated to increase neutrophil counts and to reduce the incidence and duration of infection-related events.
Slovenian: - Pri otrocih ali odraslih bolnikih s hudo prirojeno, ciklično ali idiopatsko nevtropenijo z absolutnim številom nevtrofilcev (ANC - Absolute Neutrophil Count) ≤ 0,5 x 109/l in s hudimi ali ponavljajočimi se okužbami v anamnezi je indicirana dolgotrajna uporaba filgrastima za povečanje števila nevtrofilcev in zmanjšanje pogostnosti pojavljanja in trajanja z okužbami povezanih zapletov.
English: Cutaneous vasculitisa Sweets syndrome (acute febrile neutrophilic dermatosis)
Slovenian: Sweetov sindrom (akutna febrilna nevtrofilna dermatoza)
English: Filgrastim should be administered daily by subcutaneous injection until the neutrophil count has reached and can be maintained at more than 1.5 x 109/l.
Slovenian: Filgrastim je treba dajati vsak dan kot subkutana injekcija, dokler število nevtrofilcev ne preseže vrednosti 1,5 x 109/l in ga je na tej ravni mogoče vzdrževati.
English: There is a positive linear correlation between the dose and the serum concentration of filgrastim, whether administered intravenously or subcutaneously.
Slovenian: Med odmerkom in serumsko koncentracijo filgrastima je pozitivna linearna koleracija, ne glede na subkutano ali intravensko uporabo.
English: 36 months.
Slovenian: 6.3 Rok uporabnosti 36 mesecev
English: There have been reports of GvHD and fatalities in patients receiving G-CSF after allogeneic bone marrow transplantation (see section 4.4 and 5.1).
Slovenian: Poročali so o reakcijah GvHD in o smrtnih primerih pri bolnikih, ki so G-CSF prejemali po alogenski presaditvi kostnega mozga (glejte poglavji 4.4 in 5.1).
English: Do not administer Filgrastim HEXAL to patients with a history of hypersensitivity to filgrastim or pegfilgrastim.
Slovenian: Zdravila Filgrastim HEXAL ne dajajte bolnikom s preobčutljivostjo na filgrastim ali pegfilgrastim v anamnezi.
English: Example: In a final volume of 20 ml, total doses of filgrastim less than 30 MU (300 μg) should be given with 0.2 ml of human serum albumin 200 mg/ml (20%) solution Ph. Eur.
Slovenian: Primer: Če je končna količina za injiciranje 20 ml, je treba vse odmerke filgrastima, manjše od 30 milijonov enot (300 µg), dati z dodatkom 0,2 ml 20 % (200 mg/ml) raztopine humanega serumskega albumina Ph. Eur.
English: Regular blood tests will be taken to monitor the number of white blood cells in your body.
Slovenian: Zaradi spremljanja števila belih krvnih celic bodo pri vas izvajali redne krvne preiskave.
English: However, the administration of melphalan, carboplatin or BCNU together with filgrastim has been shown to be effective for progenitor mobilisation.
Slovenian: Vendar pa je bilo ugotovljeno, da je izplavljanje matičnih celic ob uporabi melfalana, karboplatina ali BCNU hkrati s filgrastimom učinkovito.
English: Filgrastim HEXAL is a clear, colourless to slightly yellowish solution for injection or infusion in prefilled syringe.
Slovenian: Zdravilo Filgrastim HEXAL je bistra, brezbarvna do rahlo rumenkasta raztopina za injiciranje ali infundiranje v napolnjeni injekcijski brizgi.
English: If leukocyte counts exceed 50 x 109/l after the expected nadir, filgrastim should be discontinued immediately.
Slovenian: Če število levkocitov po pričakovanem minimumu preseže raven 50 x 109/l, je treba zdravljenje s filgrastimom takoj prekiniti.
English: • high uric acid levels in the blood, which may cause gout (hyperuricaemia) (Blood uric acid increased)
Slovenian: • visoke ravni sečne kisline v krvi, kar lahko povzroči protin (hiperurikemija)
English: Based on reported data for another filgrastim product similar to the reference filgrastim product, comparable findings plus increased foetal malformations were observed at 100 µg/kg/day, a maternally toxic dose which corresponded to a systemic exposure of approximately 50 - 90 times the exposures observed in patients treated with the clinical dose of 5 µg/kg/day.
Slovenian: V poročilu o drugem zdravilu s filgrastimom, ki je podobno referenčnemu zdravilu s filgrastimom, so primerljive ugotovitve in ugotovitve o povečani stopnji deformacij plodu pri odmerku 100 µg/kg/dan, ki je toksičen odmerek za brejo samico in ustreza sistemski izpostavljenosti, ki je približno 50 - 90-krat večja od izpostavljenosti bolnikov, zdravljenih s kliničnim odmerkom 5 µg/kg/dan.
English: The effects of filgrastim on neutropenia due to bone marrow-infiltrating infection or malignancy have not been well established.
Slovenian: Učinki filgrastima na nevtropenijo, ki je posledica infiltracije kostnega mozga z okužbo ali malignim obolenjem, niso dobro raziskani.
English: The onset of pulmonary signs, such as cough, fever and dyspnoea in association with radiological signs of pulmonary infiltrates and deterioration in pulmonary function may be preliminary signs of acute respiratory distress syndrome (ARDS).
Slovenian: Začetek pojavljanja pljučnih znakov, na primer kašlja, zvišane telesne temperature in dispneje, ob hkratnih radioloških znakih pljučnih infiltratov in ob slabšanju delovanja pljuč lahko pomeni začetek sindroma akutne dihalne stiske (ARDS - Acute Respiratory Distress Syndrome).
English: Filgrastim should not be used to increase the dose of cytotoxic chemotherapy beyond established dosage regimens.
Slovenian: Filgrastima se ne sme uporabljati za povečevanje odmerka citotoksične kemoterapije preko odmerkov iz uveljavljenih načinov odmerjanja.
English: Following subcutaneous administration of recommended doses, serum concentrations were maintained above 10 ng/ml for 8 - 16 hours.
Slovenian: se je serumska koncentracija vzdrževala nad vrednostjo 10 ng/ml 8 - 16 ur.
English: Diluted filgrastim may be adsorbed to glass and plastic materials, unless it is diluted in glucose 50 mg/ml (5%) solution (see section 6.6).
Slovenian: Razredčen filgrastim se lahko adsorbira na steklo in plastične materiale, razen v primeru, če je razredčen z raztopino glukoze s koncentracijo 50 mg/ml (5 %) (glejte poglavje 6.6).
English: Studies of filgrastim in patients with severe impairment of renal or hepatic function demonstrate that it exhibits a similar pharmacokinetic and pharmacodynamic profile to that seen in normal individuals.
Slovenian: Raziskave uporabe filgrastima pri bolnikih z močno zmanjšanim delovanjem ledvic ali jeter kažejo, da ima filgrastim pri teh bolnikih podoben farmakokinetični in farmakodinamski profil kot ga je mogoče opaziti pri zdravih posameznikih.
English: • if you experience a cough, fever and difficulty breathing (dyspnoea) as this can be a sign of Acute Respiratory Distress Syndrome (ARDS).
Slovenian: • če pri vas pride do pojava kašlja, zvišane telesne temperature in težav z dihanjem (dispneja), ker je lahko to znak sindroma akutne dihalne stiske (ARDS).
English: When administered for PBPC mobilisation, filgrastim should be discontinued or its dosage should be reduced if the leukocyte counts rise to > 70 x 109/l.
Slovenian: Pri dajanju filgrastima za izplavljanje matičnih celic v periferno kri je treba z njegovim dajanjem prenehati ali njegov odmerek zmanjšati, če se število levkocitov poveča na > 70 x 109/l.
English: The safety and efficacy of filgrastim have not been assessed in normal donors < 16 years or > 60 years.
Slovenian: Varnost in učinkovitost filgrastima pri zdravih darovalcih, mlajših od 16 ali starejših od 60 let, nista bili ocenjeni.
English: Accidental exposure to freezing temperatures does not adversely affect the stability of filgrastim.
Slovenian: Naključna izpostavljenost temperaturam v območju zmrzišča nima neugodnega vpliva na stabilnost filgrastima.
English: Remove one syringe from the pack and remove the protective cap from the injection needle.
Slovenian: Iz ovojnine vzemite eno injekcijsko brizgo in z injekcijske igle odstranite zaščitni pokrovček.
English: If you become pregnant during Filgrastim HEXAL treatment, please inform your doctor.
Slovenian: Če zanosite med zdravljenjem z zdravilom Filgrastim HEXAL, se posvetujte z zdravnikom.
English: • redness of the skin (erythema)
Slovenian: • rdečica na koži (eritem)
English: Myelodysplastic syndrome or Chronic myeloid leukemia The safety and efficacy of filgrastim administration in patients with myelodysplastic syndrome, or chronic myelogenous leukaemia have not been established.
Slovenian: Mielodisplastični sindrom ali kronična mieloična levkemija Varnost in učinkovitost dajanja filgrastima pri bolnikih z mielodisplastičnim sindromom ali kronično mieloično levkemijo nista bili ugotovljeni.
English: • abnormal x-rays of the lungs (lung infiltration)
Slovenian: • nenormalni rentgenski posnetki pljuč (pljučna infiltracija)
English: • to increase the number of white blood cells after treatment with chemotherapy to help prevent infections;
Slovenian: • za povečanje števila belih krvnih celic po zdravljenju s kemoterapijo, kot pomoč pri preprečevanju okužb;
English: Other medicines and Filgrastim HEXAL
Slovenian: Druga zdravila in zdravilo Filgrastim HEXAL
English: In patients receiving cytotoxic chemotherapy, a transient increase in neutrophil counts is typically seen 1 - 2 days after initiation of filgrastim therapy.
Slovenian: Pri bolnikih, pri katerih se izvaja zdravljenje s citotoksično kemoterapijo, se število nevtrofilcev 1 do 2 dni po začetku zdravljenja s filgrastimom praviloma prehodno poveča.
English: Dilution prior to administration (optional)
Slovenian: Redčenje pred uporabo (ni obvezno)
English: Once the neutrophil nadir has been passed, the daily dose of filgrastim should be titrated against the neutrophil response as follows:
Slovenian: Ko preide obdobje najmanjšega števila nevtrofilcev, je treba dnevni odmerek filgrastima prilagoditi glede na odziv nevtrofilcev takole:
English: These autologous PBPCs may be harvested and infused after high-dose cytotoxic therapy, either in place of, or in addition to bone marrow transplantation.
Slovenian: Te avtologne matične celice (PBPC) je mogoče pridobiti oziroma odvzeti in jih infundirati po citotoksičnem zdravljenju z velikimi odmerki, bodisi namesto presaditve kostnega mozga ali kot dodatek k njej.
English: A meta-analysis of allogeneic transplant studies, including the results of nine prospective randomized trials, eight retrospective studies and one case-controlled study, did not detect an effect on the risks of acute GvHD, chronic GvHD or early treatment-related mortality.
Slovenian: vključno z rezultati devetih prospektivnih randomiziranih preskušanj, osem retrospektivnih študij in ena s primerom nadzorovana študija, niso zaznale vpliva na tveganje za pojav akutne reakcije presadka proti gostitelju (GvHD), kronične reakcije presadka proti gostitelju, in zgodnje, z zdravljenjem povezane smrtnosti.
English: Do not take a double dose to make up for any missed doses.
Slovenian: Ne injicirajte dvojnega odmerka, če ste pozabili prejšnji odmerek.
English: The dosage recommendations in paediatric patients are the same as those in adults receiving myelosuppressive cytotoxic chemotherapy.
Slovenian: Priporočila za odmerjanje pri pediatričnih bolnikih so enaka kot pri odraslih, ki se zdravijo z mielosupresivno citotoksično kemoterapijo.
English: Depress the plunger slowly and evenly until the entire dose has been given and the plunger cannot be depressed any further.
Slovenian: Bat počasi in enakomerno pritisnite navzdol, dokler se ne vbrizga celotni odmerek in bata ni mogoče potisniti še naprej.
English: How to store Filgrastim HEXAL Contents of the pack and other information
Slovenian: Shranjevanje zdravila Filgrastim HEXAL Vsebina pakiranja in dodatne informacije
English: After injecting the liquid, remove the needle and let go of your skin.
Slovenian: Po vbrizganju raztopine iglo izvlecite in kožo izpustite.
English: Following termination of filgrastim therapy, circulating neutrophil counts decrease by 50% within 1 - 2 days, and to normal levels within 1 - 7 days.
Slovenian: Po koncu zdravljenja s filgrastimom se število nevtrofilcev v obtoku v 1 do 2 dneh zmanjša za 50 %, v normalno območje pa povrne v 1 do 7 dneh.
English: • disease which causes bones to become less dense, making them weaker, more brittle and likely to break (osteoporosis)
Slovenian: • bolezen, ki povzroča, da kosti postajajo manj trdne, oslabele, krhke in bolj lomljive
English: Relative Risk (95% CI) of GvHD and TRM Following treatment with G-CSF after bone marrow transplantation Publication
Slovenian: Relativno tveganje (95 % interval zaupanja) za pojav reakcije presadka proti gostitelju (GvHD) in z zdravljenjem povezane smrtnosti (TRM) po zdravljenju z G-CSF po presaditvi kostnega mozga
English: Infusion of PBPC accelerates haematopoietic recovery reducing the duration of risk for haemorrhagic complications and the need for platelet transfusions.
Slovenian: Infuzija matičnih celic (PBPC) pospeši hematopoetsko okrevanje, tako skrajša obdobje tveganja za pojav zapletov s krvavitvami in zmanjša potrebo po transfuzijah trombocitov.
English: The degree of variation between individual patients and between laboratory assays of CD34+ cells mean that direct comparison between different studies is difficult.
Slovenian: Stopnja variabilnosti med posameznimi bolniki in med laboratorijskimi preverjanji celic CD34+
English: 4 - 5 consecutive days allows a collection of ≥ 4 x 106 CD34+ cells/kg recipient body weight in the majority of the donors after two leukaphereses.
Slovenian: (10 µg/kg/dan) 4 do 5 zaporednih dni omogoča pridobitev ≥ 4 x 106 celic CD34+/kg telesne mase prejemnika po dveh levkaferezah.
English: Filgrastim HEXAL stimulates the bone marrow to produce new white cells quickly.
Slovenian: Zdravilo Filgrastim HEXAL spodbuja kostni mozeg k hitremu proizvajanju novih belih krvnih celic.
English: In patients with known bone marrow infiltrating infections or malignancy, consider appropriate therapy for treatment of the underlying condition in addition to administration of filgrastim for treatment of neutropenia.
Slovenian: Pri bolnikih z znano infiltracijo okužbe ali malignim obolenjem v kostni mozeg je treba poleg filgrastima, za zdravljenje nevtropenije, uporabiti še primerno zdravljenje osnovne bolezni.
English: Please tell your doctor before starting treatment if you have: - osteoporosis (bone disease); - sickle cell anaemia, as Filgrastim HEXAL may cause sickle cell crisis.
Slovenian: Pred začetkom zdravljenja zdravniku povejte, če imate: - osteoporozo (bolezen kosti).
English: Since lithium promotes the release of neutrophils, lithium is likely to potentiate the effect of filgrastim.
Slovenian: Litij pospešuje sproščanje nevtrofilcev, zato lahko okrepi učinek filgrastima.
English: • changes in blood chemistry
Slovenian: • spremembe v krvni kemiji • reakcija na transfuzijo
English: Accidental freezing will not harm Filgrastim HEXAL.
Slovenian: Nenamerno zamrzovanje ne škoduje zdravilu Filgrastim HEXAL.
English: You will normally receive your first dose of Filgrastim HEXAL at least 24 hours after your chemotherapy and at least 24 hours after receiving your bone marrow transplant.
Slovenian: Običajno boste prvi odmerek zdravila Filgrastim HEXAL prejeli vsaj 24 ur po kemoterapiji in vsaj 24 ur po presaditvi kostnega mozga.
English: The recommended starting dose is 1.2 MU/kg/day (12 μg/kg/day) as a single dose or in divided doses.
Slovenian: Priporočeni začetni odmerek je 1,2 M e./kg/dan (12 µg/kg/dan), v enkratnem odmerku ali v deljenih odmerkih.
English: If required, Filgrastim HEXAL may be diluted in glucose 50 mg/ml (5%) solution.
Slovenian: Če je potrebno, se zdravilo Filgrastim HEXAL lahko razredči v 5 % (50 mg/ml) raztopini glukoze.