FrancophonIA/ELRC3.0 huggingface dataset:
English: Hypoglycaemia when used in combination with other anti-hyperglycaemic medicinal products In clinical trials of Ristaben as monotherapy and as part of combination therapy with medicinal products not known to cause hypoglycaemia (i.e. metformin and/or a PPAR agonist), rates of hypoglycaemia reported with sitagliptin were similar to rates in patients taking placebo.
Danish: Hypoglykæmi i kombination med andre anti-hyperglykæmiske lægemidler Der er foretaget kliniske undersøgelser af Ristaben som monoterapi og som del af kombinationsbehandling med lægemidler, der ikke er kendt for at medføre hypoglykæmi (dvs. metformin og/eller en PPAR-agonist).
English: Some patients have experienced the following side effects while taking sitagliptin in combination with pioglitazone and metformin:
Danish: Nogle patienter har oplevet følgende bivirkninger, når de har taget sitagliptin sammen med pioglitazon og metformin:
English: Immune system disorders hypersensitivity reactions including anaphylactic responses
Danish: Overfølsomhedsreaktioner herunder anafylaktiske reaktioner
English: A 24-week placebo-controlled study was designed to evaluate the efficacy and safety of sitagliptin (100 mg once daily) added to insulin (at a stable dose for at least 10 weeks) with or without metformin (at least 1,500 mg).
Danish: En 24-ugers placebokontrolleret undersøgelse blev designet til at evaluere effekt og sikkerhed af sitagliptin (100 mg en gang dagligt) som supplement til insulin (ved en stabil dosis i mindst 10 uger) med eller uden metformin (mindst 1.500 mg).
English: Some patients have experienced the following side effects while taking sitagliptin in combination with a sulphonylurea and metformin:
Danish: Nogle patienter har oplevet følgende bivirkninger, når de har taget sitagliptin sammen med et sulfonylurinstof og metformin:
English: • a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.
Danish: • et sulfonylurinstof og metformin, når diæt og motion plus dual behandling med disse lægemidler ikke giver tilstrækkelig glykæmisk kontrol.
English: A 24-week placebo-controlled study involving 660 patients was designed to evaluate the insulin-sparing efficacy and safety of sitagliptin (100 mg once daily) added to insulin glargine with or without metformin (at least 1,500 mg) during intensification of insulin therapy.
Danish: En 24-ugers placebokontrolleret undersøgelse med 660 patienter blev designet til at vurdere den insulinbesparende effekt og sikkerheden af sitagliptin (100 mg en gang dagligt) som supplement til insulin glargin med eller uden metformin (mindst 1.500 mg) under optrapning af insulinbehandling.
English: The decrease in body weight with the combination of sitagliptin and metformin was similar to that observed with metformin alone or placebo; there was no change from baseline for patients on sitagliptin alone.
Danish: Reduktionen i kropsvægt med kombinationen af sitagliptin og metformin var den samme som den, der blev observeret med metformin alene eller placebo.
English: Secondary Composite Endpoint (Cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke)
Danish: Sekundært sammensat endepunkt (Kardiovaskulær død, ikke-letalt myokardieinfarkt, ikke-letal apopleksi)
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Danish: Brug af anden medicin sammen med Ristaben Fortæl det altid til lægen eller på apoteket, hvis De bruger anden medicin eller har gjort det for nylig.
English: Primary Composite Endpoint (Cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina)
Danish: Primært sammensat endepunkt (Kardiovaskulær død, ikke-letalt myokardieinfarkt, ikke-letal apopleksi eller hospitalsindlæggelse pga. ustabil angina)
English: Initial therapy (twice daily) Sitagliptin 50 mg + metformin 1,000 mg (N=178)
Danish: Initialbehandling (to gange dagligt) Sitagliptin 50 mg + metformin 1000 mg (N=178)
English: The mean volume of distribution at steady state following a single 100-mg intravenous dose of sitagliptin to healthy subjects is approximately 198 litres.
Danish: Det gennemsnitlige fordelingsvolumen ved steady state efter en enkelt intravenøs dosis på 100 mg sitagliptin til raske personer er ca. 198 l. Den fraktion af sitagliptin, som er reversibelt bundet til plasmaproteiner, er lav (38%).
English: A 26-week placebo-controlled study was designed to evaluate the efficacy and safety of sitagliptin (100 mg once daily) added to the combination of pioglitazone and metformin.
Danish: Et 26-ugers placebokontrolleret studie blev designet til at evaluere sitagliptins effekt og sikkerhed (100 mg en gang dagligt) som supplement til kombinationen pioglitazon plus metformin.
English: Sitagliptin 100 mg once daily (N= 193) Sitagliptin 100 mg once daily (N= 229)
Danish: Sitagliptin 100 mg en gang dagligt (N=229)
English: Ristaben contains the active substance sitagliptin which is a member of a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) that lowers blood sugar levels in adult patients with type 2 diabetes mellitus.
Danish: Ristaben indeholder det aktive stof sitagliptin, som tilhører en klasse af lægemidler, som kaldes DPP4-hæmmere (dipeptylpeptidase-4-hæmmere).
English: Minimal increases in QTc, not considered to be clinically relevant, were observed in one study at a dose of 800 mg sitagliptin.
Danish: Minimale forlængelser af QTc-intervallet blev observeret i et studie med en 800 mg dosis sitagliptin, men blev ikke anset for at være klinisk relevante.
English: Initial therapy (twice daily) Sitagliptin 50 mg + metformin 500 mg (N=183)
Danish: Initialbehandling (to gange dagligt) Sitagliptin 50 mg + metformin 500 mg (N=183)
English: How to take Ristaben
Danish: Sådan skal De tage Ristaben
English: Round, beige film-coated tablet with “277” on one side.
Danish: Rund, beige, filmovertrukken tablet mærket med ”277” på den ene side.
English: To achieve plasma concentrations of sitagliptin similar to those in patients with normal renal function, lower dosages are recommended in patients with GFR < 45 mL/min (see section 4.2).
Danish: For at opnå den samme plasmakoncentration for sitagliptin som hos patienter med normal nyrefunktion bør patienter med GFR <45 ml/min have lavere doser (se pkt.
English: Therefore, to reduce the risk of hypoglycaemia, a lower dose of sulphonylurea or insulin may be considered (see section 4.2).
Danish: Derfor bør en lavere dosis af sulfonylurinstof eller insulin overvejes for at reducere risikoen for hypoglykæmi (se pkt.
English: A 24-week placebo-controlled study was designed to evaluate the efficacy and safety of sitagliptin (100 mg once daily) added to glimepiride alone or glimepiride in combination with metformin.
Danish: En 24-ugers placebokontrolleret undersøgelse blev designet til at evaluere effekten samt sikkerheden af sitagliptin (100 mg en gang dagligt) som supplement til glimepirid alene eller glimepirid i kombination med metformin.
English: In the intention-to-treat population, among patients who were using insulin and/or a sulfonylurea at baseline, the incidence of severe hypoglycaemia was 2.7 % in sitagliptin-treated patients and 2.5 % in placebo-treated patients; among patients who were not using insulin and/or a sulfonylurea at baseline, the incidence of severe hypoglycaemia was 1.0 % in sitagliptin-treated patients and 0.7 % in placebo-treated patients.
Danish: I intention to treat-populationen var incidensen af svær hypoglykæmi blandt patienter, som fik insulin og/eller et sulfonylurinstof ved baseline, 2,7% hos patienter i sitagliptin-armen og 2,5% hos patienter i placebo-armen.
English: Marketing Authorisation Holder Merck Sharp & Dohme B.V. Waarderweg 39
Danish: Indehaver af markedsføringstilladelsen Merck Sharp & Dohme B.V.
English: The overall incidence of serious adverse events in patients receiving sitagliptin was similar to that in patients receiving placebo.
Danish: Den samlede incidens af alvorlige bivirkninger hos patienter i sitagliptin-armen var den samme som hos patienter i placeboarmen.
English: Sitagliptin 100 mg once daily added to ongoing insulin (+/- metformin) therapy (N=305)
Danish: Sitagliptin 100 mg en gang dagligt som supplement til insulin (+/- metformin) behandling (N=305)
English: Sitagliptin 100 mg once daily added to ongoing glimepiride + metformin therapy (N=115)
Danish: Sitagliptin 100 mg en gang dagligt som supplement til glimepirid + metforminbehandling (N=115)
English: Following oral administration of a 100-mg dose to healthy subjects, sitagliptin was rapidly absorbed, with peak plasma concentrations (median Tmax) occurring 1 to 4 hours post-dose, mean plasma AUC of sitagliptin was 8.52 M•hr, Cmax was 950 nM.
Danish: Peakplasmakoncentrationer (median Tmax) forekom 1-4 timer efter dosering, gennemsnitlig plasma-AUC for sitagliptin var 8,52 µM•hr, Cmax var 950 nM. Sitagliptins absolutte biotilgængelighed er ca. 87%.
English: Other patient characteristics
Danish: Andre patientkarakteristika
English: Round, pink film-coated tablet with “221” on one side.
Danish: Rund, lyserød, filmovertrukken tablet mærket med ”221” på den ene side.
English: Sitagliptin 100 mg once daily added to ongoing glimepiride therapy (N=102)
Danish: Sitagliptin 100 mg en gang dagligt som supplement til glimepiridbehandling (N=102)
English: The TECOS was a randomised in 14,671 patients in the intention-to-treat population with an HbA1c of ≥ 6.5 to 8.0 % with established CV disease who received sitagliptin (7,332) 100 mg daily (or 50 mg daily if the baseline eGFR was ≥ 30 and < 50 mL/min/1.73 m2) or placebo (7,339) added to usual care targeting regional standards for HbA1c and CV risk factors.
Danish: Patienterne fik sitagliptin (7.332) 100 mg dagligt (eller 50 mg dagligt, hvis eGFR ved baseline var ≥ 30 og < 50 ml/min/1,73 m2) eller placebo (7.339) som supplement til standardbehandling målrettet de regionale standarder for HbA1c og kardiovaskulære risikofaktorer.
English: Some patients have experienced the following side effects after adding sitagliptin to metformin: Common (may affect up to 1 in 10 people): low blood sugar, nausea, flatulence, vomiting Uncommon (may affect up to 1 in 100 people): stomach ache, diarrhoea, constipation, drowsiness.
Danish: Nogle patienter har oplevet følgende bivirkninger efter at sitagliptin er blevet føjet til metformin: Almindelige (kan berøre op til 1 ud af 10): Lavt blodsukker, kvalme, øget luftafgang fra tarmen, opkastning.
English: In clinical studies, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, warfarin, or oral contraceptives, providing in vivo evidence of a low propensity for causing interactions with substrates of CYP3A4, CYP2C8, CYP2C9, and organic cationic transporter (OCT).
Danish: I kliniske undersøgelser ændrede sitagliptin ikke farmakokinetikken for metformin, glyburid, simvastatin, rosiglitazon, warfarin eller orale kontraceptiva signifikant.
English: Sitagliptin 100 mg once daily added to ongoing pioglitazone therapy (N=163)
Danish: Sitagliptin 100 mg en gang dagligt som supplement til pioglitazonbehandling (N=163)
English: - type 1 diabetes - diabetic ketoacidosis (a complication of diabetes with high blood sugar, rapid weight loss,
Danish: - Komplikation til diabetes med forhøjet blodsukker, hurtigt vægttab, kvalme eller opkastning
English: Merck Sharp & Dohme B.V. Tel.: 0800 9999000 (+31 23 5153153) medicalinfo.nl@merck.com
Danish: Tel.: 0800 9999000 (+31 23 5153153) medicalinfo.nl@merck.com
English: The incidence of hypoglycaemia was also similar in patients treated with sitagliptin or placebo.
Danish: Incidensen af hypoglykæmi var også den samme hos sitagliptinbehandlede og placebobehandlede patienter.
English: 23 times the clinical exposure level.
Danish: Hos hunde er der ved et eksponeringsniveau på over 23 gange den kliniske eksponering observeret forbigående behandlingsrelaterede fysiske tegn.
English: Round, light beige film-coated tablet with “112” on one side.
Danish: Rund, lys beige, filmovertrukken tablet mærket med ”112” på den ene side.
English: - If you have any further questions, ask your doctor, pharmacist, or nurse.
Danish: Er De i tvivl, så spørg lægen eller apotekspersonalet.
English: To achieve plasma concentrations of sitagliptin similar to those in patients with normal renal function, lower dosages are recommended in patients with GFR < 45 mL/min, as well as in ESRD patients requiring haemodialysis or peritoneal dialysis (see section 4.2 and 5.2).
Danish: For at opnå den samme plasmakoncentration for sitagliptin som hos patienter med normal nyrefunktion bør patienter med GFR <45 ml/min samt ESRD-patienter med behov for hæmodialyse eller peritonealdialyse have lavere doser (se pkt.
English: For adult patients with type 2 diabetes mellitus, Ristaben is indicated to improve glycaemic control:
Danish: Ristaben er indiceret til at forbedre den glykæmiske kontrol:
English: What Ristaben looks like and contents of the pack
Danish: Udseende og pakningsstørrelser
English: Ristaben 100 mg tablets Sitagliptin
Danish: Ristaben 100 mg tabletter sitagliptin
English: Film coating: poly(vinyl alcohol) macrogol 3350 talc (E553b) titanium dioxide (E171) red iron oxide (E172) yellow iron oxide (E172)
Danish: Talcum (E553b) Titandioxid (E171) Rød jernoxid (E172) Gul jernoxid (E172)
English: Ristaben 25 mg tablets Sitagliptin
Danish: Ristaben 25 mg tabletter sitagliptin
English: A study comparing sitagliptin at 25 or 50 mg once daily to glipizide at 2.5 to 20 mg/day was conducted in patients with moderate to severe renal impairment.
Danish: Der er hos patienter med moderat til svær nyreinsufficiens udført en undersøgelse, hvor sitagliptin 25 eller 50 mg dagligt blev sammenlignet med glipizid 2,5 mg til 20 mg/dag.
English: What Ristaben is and what it is used for What you need to know before you take Ristaben How to take Ristaben
Danish: Det skal De vide, før De begynder at tage Ristaben Sådan skal De tage Ristaben Bivirkninger
English: In a pre-/postnatal development study performed in rats sitagliptin showed no adverse effects.
Danish: Sitagliptin viste ingen bivirkninger i en præ- og postnatal udviklingsundersøgelse udført med rotter.
English: There is no clinical experience in patients with severe hepatic impairment (Child-Pugh score > 9).
Danish: Dosisjustering af Ristaben er ikke nødvendig hos patienter med let eller moderat leverinsufficiens (Child-Pugh score ≤9).
English: Incisor teeth abnormalities were observed in rats at exposure levels 67 times the clinical exposure level; the no-effect level for this finding was 58-fold based on the 14-week rat study.
Danish: Abnormiteter af fortænderne observeredes hos rotter ved en eksponering, der var 67 gange højere end det kliniske eksponeringsniveau.
English: (pancreatitis).
Danish: (diabetisk ketoacidose).
English: Ristaben 50 mg tablets Sitagliptin
Danish: Ristaben 50 mg tabletter sitagliptin
English: Sitagliptin 100 mg once daily added to ongoing metformin therapy (N=453)
Danish: Kombinationsterapiundersøgelser Sitagliptin 100 mg en gang dagligt som supplement til metforminbehandling (N=453)
English: Ristaben 100 mg film-coated tablets
Danish: Ristaben 100 mg filmovertrukne tabletter
English: EU/1/10/621/013 14 film-coated tablets EU/1/10/621/014 28 film-coated tablets EU/1/10/621/023 30 film-coated tablets EU/1/10/621/015 56 film-coated tablets EU/1/10/621/016 84 film-coated tablets EU/1/10/621/024 90 film-coated tablets EU/1/10/621/017 98 film-coated tablets EU/1/10/621/018 50 x 1 film-coated tablets
Danish: EU/1/10/621/013 14 filmovertrukne tabletter EU/1/10/621/014 28 filmovertrukne tabletter EU/1/10/621/023 30 filmovertrukne tabletter EU/1/10/621/015 56 filmovertrukne tabletter EU/1/10/621/016 84 filmovertrukne tabletter EU/1/10/621/024 90 filmovertrukne tabletter EU/1/10/621/017 98 filmovertrukne tabletter EU/1/10/621/018 50 x 1 filmovertrukne tabletter
English: EU/1/10/621/001 14 film-coated tablets EU/1/10/621/002 28 film-coated tablets EU/1/10/621/019 30 film-coated tablets EU/1/10/621/003 56 film-coated tablets EU/1/10/621/004 84 film-coated tablets EU/1/10/621/020 90 film-coated tablets EU/1/10/621/005 98 film-coated tablets EU/1/10/621/006 50 x 1 film-coated tablets
Danish: EU/1/10/621/001 14 filmovertrukne tabletter EU/1/10/621/002 28 filmovertrukne tabletter EU/1/10/621/019 30 filmovertrukne tabletter EU/1/10/621/003 56 filmovertrukne tabletter EU/1/10/621/004 84 filmovertrukne tabletter EU/1/10/621/020 90 filmovertrukne tabletter EU/1/10/621/005 98 filmovertrukne tabletter EU/1/10/621/006 50 x 1 filmovertrukne tabletter
English: Ristaben 25 mg film-coated tablets
Danish: Ristaben 25 mg filmovertrukne tabletter
English: EU/1/10/621/007 14 film-coated tablets EU/1/10/621/008 28 film-coated tablets EU/1/10/621/021 30 film-coated tablets EU/1/10/621/009 56 film-coated tablets EU/1/10/621/010 84 film-coated tablets EU/1/10/621/022 90 film-coated tablets EU/1/10/621/011 98 film-coated tablets EU/1/10/621/012 50 x 1 film-coated tablets
Danish: EU/1/10/621/007 14 filmovertrukne tabletter EU/1/10/621/008 28 filmovertrukne tabletter EU/1/10/621/021 30 filmovertrukne tabletter EU/1/10/621/009 56 filmovertrukne tabletter EU/1/10/621/010 84 filmovertrukne tabletter EU/1/10/621/022 90 filmovertrukne tabletter EU/1/10/621/011 98 filmovertrukne tabletter EU/1/10/621/012 50 x 1 filmovertrukne tabletter
English: - This medicine has been prescribed for you only.
Danish: - Lægen har ordineret Ristaben til Dem personligt.
English: Posology
Danish: Myalgi
English: For the full list of excipients, see section 6.1.
Danish: 6.1 (se pkt.
English: Sitagliptin 100 mg once daily provided significant improvements in glycaemic parameters compared with placebo in two 24-week studies of sitagliptin as add-on therapy, one in combination with metformin and one in combination with pioglitazone.
Danish: I to 24-ugers undersøgelser gav sitagliptin 100 mg en gang dagligt som supplerende behandling, den ene i kombination med metformin og den anden med pioglitazon, en signifikant glykæmisk forbedring, sammenlignet med placebo.
English: Ristaben 25 mg film-coated tablets Sitagliptin
Danish: Ristaben 25 mg filmovertrukne tabletter sitagliptin
English: Ristaben 50 mg film-coated tablets
Danish: Ristaben 50 mg filmovertrukne tabletter
English: Hepatic impairment
Danish: Akut nyresvigt
English: Paediatric No studies with Ristaben have been performed in paediatric patients.
Danish: Børn Der er ikke udført undersøgelser med anvendelse af Ristaben til børn.
English: Ristaben 100 mg film-coated tablets Sitagliptin
Danish: Ristaben 100 mg filmovertrukne tabletter sitagliptin
English: Least squares means adjusted for prior antihyperglycaemic therapy status and baseline value.
Danish: Population; alle behandlede patienter (analyse med henblik på behandling) Gennemsnit ved mindste kvadraters metode justeret for status for tidligere antihyperglykæmisk behandling og baseline-værdi.
English: Ristaben 50 mg film-coated tablets Sitagliptin
Danish: Ristaben 50 mg filmovertrukne tabletter sitagliptin
English: Musculoskeletal and connective tissue disorders arthralgia
Danish: Knogler, led, muskler og bindevæv Artralgi
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 100 mg sitagliptin.
Danish: Hver filmovertrukken tablet (tablet) indeholder sitagliptin phosphatmonohydrat, der svarer til 100 mg sitagliptin.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 25 mg sitagliptin.
Danish: Hver filmovertrukken tablet (tablet) indeholder sitagliptin phosphatmonohydrat, der svarer til 25 mg sitagliptin.
English: Each tablet contains sitagliptin phosphate monohydrate equivalent to 100 mg of sitagliptin.
Danish: Hver tablet indeholder sitagliptin phosphatmonohydrat svarende til 100 mg sitagliptin.
English: Each tablet contains sitagliptin phosphate monohydrate equivalent to 25 mg of sitagliptin.
Danish: Hver tablet indeholder sitagliptin phosphatmonohydrat svarende til 25 mg sitagliptin.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 50 mg sitagliptin.
Danish: Hver filmovertrukken tablet (tablet) indeholder sitagliptin phosphatmonohydrat, der svarer til 50 mg sitagliptin.
English: Merck Sharp & Dohme B.V. Waarderweg 39
Danish: Merck Sharp & Dohme B.V.
English: Each tablet contains sitagliptin phosphate monohydrate equivalent to 50 mg of sitagliptin.
Danish: Hver tablet indeholder sitagliptin phosphatmonohydrat svarende til 50 mg sitagliptin.
English: Common dizziness
Danish: Bulløs pemfigoid
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 100 mg sitagliptin.
Danish: Hver tablet indeholder sitagliptin-phosphatmonohydrat, svarende til 100 mg sitagliptin.
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 25 mg sitagliptin.
Danish: Hver tablet indeholder sitagliptin-phosphatmonohydrat, svarende til 25 mg sitagliptin.
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 50 mg sitagliptin.
Danish: Hver tablet indeholder sitagliptin-phosphatmonohydrat, svarende til 50 mg sitagliptin.
English: Bullous pemphigoid
Danish: Kutan vaskulitis
English: These may be the signs of an allergic reaction.
Danish: Dette kan være tegn på en allergisk reaktion.
English: Risk Management Plan was not submitted.
Danish: Der er ikke indsendt et risikostyringsprogram.
English: No new safety concerns were noted during this long-term follow-up.
Danish: Ingen nye sikkerhedsricisi blev konstateret under denne langtidsopfølgning.
English: The clinical relevance of this interaction is uncertain.
Danish: Den kliniske relevans af denne interaktion er uvis.
English: Neutropenia, including severe neutropenia
Danish: Neutropeni, inklusive svær neutropeni
English: The application is based on a reference medicinal product for which no safety concerns requiring additional risk minimization activities have been identified.
Danish: Ansøgningen er baseret på et referencelægemiddel, for hvilket der ikke er identificeret nogen sikkerhedsanliggender, der kræver yderligere risikominimeringsaktiviteter.
English: These may be due to rare decrease of some blood cells.
Danish: Dette kan ske på grund af et sjældent fald i visse blodlegemer.
English: In addition, your doctor may identify changes in your blood or urine test results.
Danish: I øvrigt kan Deres læge eventuelt finde ændringer i resultaterne af Deres blod- eller urinprøver.
English: However, clopidogrel and ASA have been administered together for up to one year (see
Danish: Imidlertid er clopidogrel og ASA administreret samtidig i op til et år (se pkt.
English: These results indicate that clopidogrel can be administered with pantoprazole.
Danish: Disse resultater indikerer, at clopidogrel kan administreres sammen med pantoprazol.
English: Taking Clopidogrel Qualimed with food and drink Clopidogrel Qualimed may be taken with or without food.
Danish: Brug af Clopidogrel Qualimed sammen med mad og drikke Clopidogrel Qualimed kan tages sammen med eller uden mad.
English: Consequently, a direct effect (slight toxicity), or an indirect effect (low palatability) cannot be
Danish: Følgelig kan en direkte virkning (let toksicitet) eller en indirekte virkning (mindre velsmagende) ikke udelukkes.
English: Do not take a double dose to make up for a forgotten tablet dose.
Danish: De må ikke tage en dobbeltdosis som erstatning for en glemt dosis.
English: None of these analyses were adequately sized to detect differences in outcome in poor metabolisers.
Danish: Ingen af disse analyser var tilstrækkeligt store til at kunne detektere forskelle i outcome hos personer med ringepoor metabolisme.
English: The most common side effect is bleeding.
Danish: Den mest almindelige bivirkning er blødning.
English: Esomeprazole is expected to give a similar interaction with clopidogrel.
Danish: Esomeprazol forventes at give en lignende interaktion med clopidogrel