FrancophonIA/ELRC3.0 huggingface dataset:
English: Nasonex is used to treat the symptoms of hayfever (also called seasonal allergic rhinitis) and perennial rhinitis in adults and children aged 3 and older.
Croatian: Nasonex se primjenjuje za liječenje simptoma peludne groznice (tzv. sezonskog alergijskog rinitisa) i cjelogodišnjeg rinitisa u odraslih i djece u dobi od 3 godine i starijih.
English: Each spray contains 50 micrograms of mometasone furoate, as the monohydrate.
Croatian: Jedna sprej doza sadrži 50 mikrograma mometazonfuroata, u obliku hidrata.
English: Non-nasal Symptoms
Croatian: Nenazalni simptomi
English: Effects noted were umbilical hernia in rats, cleft palate in mice and gallbladder agenesis, umbilical hernia, and flexed front paws in rabbits.
Croatian: Primijećeni učinci bili su umbilikalna hernija u štakora, rascjep nepca u miševa i ageneza žučnog mjehura,
English: Prime by pumping 10 times before initial use, or 2 times if unused for 14 days or more, until a fine mist is produced.
Croatian: Pripremiti za primjenu tako da štrcnete u zrak 10 puta prije prve primjene, odnosno 2 puta ako sprej niste koristili 14 ili više dana, dok se ne postigne jednolik mlaz.
English: When corticosteroid nasal sprays are used at high doses for long periods of time, side effects may occur due to the drug being absorbed in the body.
Croatian: Kad se kortikosteroidni sprejevi za nos primjenjuju u visokim dozama tijekom dugih razdoblja, mogu nastati nuspojave zbog apsorpcije lijeka u tijelo.
English: Shake container well before each use.
Croatian: Prije svake primjene spremnik treba dobro protresti.
English: NASONEX and associated names strength pharmaceutical form [See Annex I - To be completed nationally]
Croatian: Nasonex i pridružena imena jačina farmaceutski oblik [Vidjeti Dodatak I - ispunjava država članica]
English: The usual recommended starting dose for polyposis is two actuations (50 micrograms/actuation) in each nostril once daily (total daily dose of 200 micrograms).
Croatian: Uobičajena preporučena početna doza za polipozu je dva uštrcaja (50 mikrograma/uštrcaj) u svaku nosnicu jedanput na dan (ukupna dnevna doza od 200 mikrograma).
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON NASONEX 50 µg/actuation 60 and 140 actuations
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU KUTIJA NASONEX 50 µg/uštrcaj 60 i 140 uštrcaja
English: Dispersable cellulose (microcrystalline cellulose and carmellose sodium) Glycerol
Croatian: 6.1 Popis pomoćnih tvari disperzibilna celuloza (celuloza mikrokristalična i karmelozanatrij)
English: • [To be completed nationally]
Croatian: • [Ispunjava država članica]
English: If the pump is not used for 14 days or longer, reprime the pump with 2 actuations until a uniform spray is observed, before next use.
Croatian: Ukoliko se pumpica ne koristi 14 dana ili duže, prije sljedeće primjene treba je ponovno aktivirati s 2 potiska, dok se ne postigne jednolik mlaz.
English: If you have not used the spray for 14 days or more, you need to “re-prime” the bottle by pumping the spray 2 times until a fine mist is produced.
Croatian: Ukoliko niste koristili sprej 14 dana ili više, trebate ga "ponovno pripremiti" tako da štrcnete 2 puta u zrak sve dok se ne postigne jednolik mlaz.
English: Following 12 months of treatment with NASONEX Nasal Spray in a study of patients with perennial rhinitis, there was no evidence of atrophy of the nasal mucosa; also, mometasone furoate tended to reverse the nasal mucosa closer to a normal histologic phenotype.
Croatian: Nakon 12 mjeseci liječenja NASONEX sprejem za nos u ispitivanju bolesnika s cjelogodišnjim rinitisom nije bilo dokaza atrofije sluznice nosa, a mometazonfuroat djelovao je na uspostavljanje normalnog histološkog fenotipa sluznice nosa.
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING LABEL NASONEX 50 µg/actuation 60 and 140 actuations
Croatian: PODACI KOJI SE MORAJU NALAZITI NA UNUTARNJEM PAKIRANJU NALJEPNICA NASONEX 50 µg/uštrcaj 60 i 140 uštrcaja
English: Treatment-related adverse reactions reported by system organ class and frequency Very common
Croatian: Nuspojave povezane s liječenjem prijavljene po organskim sustavima i učestalosti
English: After using the spray, wipe the nozzle carefully with a clean handkerchief or tissue and replace the dust cap.
Croatian: Nakon uporabe spreja pažljivo obrišite mlaznicu s čistim rupčićem i zatvorite zatvaračem.
English: Nasonex reduces the swelling and irritation in your nose and thereby relieving sneezing, itching and a blocked-up or runny nose caused by hay fever or perennial rhinitis.
Croatian: Nasonex smanjuje oteklinu i iritaciju u Vašem nosu te time ublažava kihanje, svrbež, začepljen nos ili curenje nosa uzrokovano peludnom groznicom ili cjelogodišnjim rinitisom.
English: 4.4 Special warnings and precautions for use
Croatian: 4.4 Posebna upozorenja i mjere opreza pri uporabi Imunosupresija
English: Nasal Polyps
Croatian: Nosni polipi
English: If symptoms are inadequately controlled, the dose may be increased to a maximum daily dose of four actuations in each nostril once daily (total dose 400 micrograms).
Croatian: Ako simptomi nisu odgovarajuće kontrolirani, doza se može povećati na maksimalnu dnevnu dozu od četiri uštrcaja u svaku nosnicu jedanput na dan (ukupna doza 400 mikrograma).
English: Upper respiratory tract infection†
Croatian: Infekcije i infestacije faringitis infekcija gornjih dišnih putova†
English: The bottle should be discarded after the labelled number of actuations or within 2 months of first use.
Croatian: Nakon što je iskorišten sav označen broj uštrcaja ili u roku od 2 mjeseca od prve primjene, bocu treba baciti.
English: Systemic effects of nasal corticosteroids may occur, particularly when prescribed at high doses for prolonged periods.
Croatian: Sistemski učinci nazalnih kortikosteroida mogu se javiti, osobito kad se propisuju u visokim dozama tijekom produljenog razdoblja.
English: The spray will need to be primed again with 2 sprays when first used after cleaning.
Croatian: • Pri prvoj primjeni nakon čišćenja sprej se mora ponovno pripremiti s 2 štrcanja.
English: There are no or limited amount of data from the use of mometasone furoate in pregnant women.
Croatian: Nema podataka ili su podaci o primjeni mometazonfuroata u trudnica ograničeni.
English: What is Nasonex used for?
Croatian: Za što se Nasonex primjenjuje?
English: Nasonex and associated names strength pharmaceutical form [See Annex I - To be completed nationally] Mometasone Furoate
Croatian: NASONEX i pridružena imena jačina farmaceutski oblik [Vidjeti Dodatak I - ispunjava država članica]
English: Children between the ages of 3 and 11 years: The usual recommended dose is one actuation (50 micrograms/actuation) in each nostril once daily (total dose 100 micrograms).
Croatian: Djeca u dobi od 3 do 11 godina: uobičajena preporučena doza je jedan uštrcaj (50 mikrograma/uštrcaj) u svaku nosnicu jedanput na dan (ukupna doza 100 mikrograma).
English: swollen face, tongue or pharynx trouble swallowing hives wheezing or trouble breathing
Croatian: • oticanje lica, jezika ili ždrijela • otežano gutanje
English: Adverse reactions are listed according to MedDRA primary system organ class.
Croatian: Nuspojave su navedene prema MedDRA klasifikaciji organskih sustava.
English: (See 4.4 Special warnings and special precautions for use with systemic corticosteroids)
Croatian: 4.5 Interakcije s drugim lijekovima i drugi oblici interakcija (Vidjeti dio 4.4 Posebna upozorenja i mjere opreza pri uporabi sistemskih kortikosteroida)
English: If symptoms are not controlled after 5 to 6 weeks, the dose may be increased to two sprays in each nostril twice daily.
Croatian: • Ukoliko se simptomi ne ublaže nakon 5 do 6 tjedana liječenja, doza se može povećati na dva uštrcaja u svaku nosnicu dvaput na dan.
English: Do Not pierce the nasal applicator.
Croatian: Nemojte bušiti nosni aplikator.
English: Within each system organ class, adverse reactions are ranked by frequency.
Croatian: Unutar svake klase organskog sustava nuspojave su navedene prema učestalosti.
English: Epistaxis Nasal burning Nasal irritation Nasal ulceration
Croatian: epistaksa peckanje nosa iritacija nosa ulceracija nosa perforacija nosnog septuma
English: Talk to your doctor or pharmacist before using Nasonex if you have or have ever had tuberculosis.
Croatian: Obratite se svom liječniku ili ljekarniku prije nego primijenite lijek Nasonex
English: Also contains : dispersible cellulose, glycerol, sodium citrate, citric acid monohydrate, polysorbate 80, benzalkonium chloride, purified water.
Croatian: • Pomoćne tvari su: disperzibilna celuloza, glicerol, natrijev citrat, citratna kiselina hidrat, polisorbat 80, benzalkonijev klorid i voda, pročišćena.
English: This leaflet was last approved in [To be completed nationally]
Croatian: Ova uputa je zadnji puta revidirana u
English: Nasonex contains benzalkonium chloride which may cause nasal irritation.
Croatian: Nasonex sadrži benzalkonijev klorid Nasonex sadrži benzalkonijev klorid koji može uzrokovati nadraženost u nosu.
English: *recorded for twice daily dosing for nasal polyposis †recorded at uncommon frequency for twice daily dosing for nasal polyposis
Croatian: *zabilježeno kod doziranja dvaput na dan za nosnu polipozu
English: There is no evidence of hypothalamic-pituitary-adrenal (HPA) axis suppression following prolonged treatment with NASONEX Nasal Spray.
Croatian: Nema dokaza o supresiji hipotalamično-hipofizno-adrenalne (HHA) osi nakon dugotrajne primjene
English: Following the use of intranasal corticosteroids, instances of increased intraocular pressure have been reported (see section 4.8).
Croatian: Nakon primjene intranazalnih kortikosteroida, prijavljeni su slučajevi povećanog intraokularnog tlaka
English: Hypersensitivity including anaphylactic reactions, angioedema, bronchospasm, and dyspnoea
Croatian: angioedem, bronhospazam i dispneju
English: Push the nozzle back onto the bottle and replace the dust cap.
Croatian: • Pričvrstite mlaznicu nazad na bocu te ju zatvorite zatvaračem.
English: The usual dose is two sprays into each nostril once a day.
Croatian: Uobičajena doza je dva uštrcaja u svaku nosnicu jedanput na dan.
English: If no improvement in symptoms is seen after 5 to 6 weeks of twice daily administration, you should contact your doctor.
Croatian: • Ukoliko unutar 5 do 6 tjedana primjenom od dvaput na dan ne dođe do poboljšanja simptoma, trebate se obratiti svom liječniku.
English: Use in adults and children over 12 years old
Croatian: Liječenje peludne groznice i cjelogodišnjeg rinitisa Primjena u odraslih i djece starije od 12 godina
English: If after 5 to 6 weeks symptoms are inadequately controlled, the dose may be increased to a daily dose of two sprays in each nostril twice daily (total daily dose of 400 micrograms).
Croatian: Ukoliko se ne uspostavi kontrola simptoma nakon 5 do 6 tjedana, dnevna doza se može povećati na dva uštrcaja u svaku nosnicu dvaput na dan (ukupna dnevna doza od 400 mikrograma).
English: Marketing Authorisation Holder and Manufacturer [See Annex I - To be completed nationally]
Croatian: Nositelj odobrenja za stavljanje gotovog lijeka u promet i proizvođač [Vidjeti Dodatak I - Ispunjava država članica]
English: NASONEX Nasal Spray is indicated for the treatment of nasal polyps in adults 18 years of age and older.
Croatian: NASONEX sprej za nos je indiciran za liječenje nosnih polipa u odraslih u dobi od 18 godina i starijih.
English: The usual starting dose is two sprays into each nostril once daily.
Croatian: Uobičajena početna doza je dva uštrcaja u svaku nosnicu jedanput na dan.
English: Do not use Nasonex if you are allergic (hypersensitive) to mometasone furoate or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični (preosjetljivi) na mometazonfuroat ili bilo koji drugi sastojak ovog lijeka
English: Local Nasal Effects
Croatian: Lokalni učinci u nosu
English: Remove the dust cap and gently pull off the nozzle.
Croatian: • Uklonite zatvarač i pažljivo skinite mlaznicu.
English: If your eyes are itching or irritated, your doctor may recommend that you use other treatments with Nasonex.
Croatian: Ako Vas svrbe oči ili su nadražene, liječnik Vam može preporučiti primjenu drugih lijekova s lijekom
English: Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Croatian: 6.6 Posebne mjere za zbrinjavanje i druga rukovanja lijekom Neiskorišteni lijek ili otpadni materijal valja zbrinuti sukladno nacionalnim propisima.
English: Benzalkonium chloride,
Croatian: Sadrži benzalkonijev klorid
English: Therefore, the patient should continue regular use to achieve full therapeutic benefit.
Croatian: Međutim, potpuna korist lijeka možda se neće postići u prvih 48 sati; stoga bolesnici moraju nastaviti s redovitom primjenom kako bi postigli potpunu terapijsku korist.
English: INFORMATION IN BRAILLE Nasonex 50 µg nasal spray [To be completed nationally]
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Nasonex 50 µg sprej za nos
English: Mometasone furoate (as the monohydrate) 50 micrograms/actuation.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Mometazonfuroat (u obliku hidrata) 50 mikrograma/uštrcaj.
English: polysorbate 80, benzalkonium chloride, purified water.
Croatian: benzalkonijev klorid; vodu, pročišćenu.
English: However, patients who are transferred from long-term administration of systemically active corticosteroids to NASONEX Nasal Spray require careful attention.
Croatian: Međutim, potreban je poseban oprez u bolesnika koji nakon dugotrajne sistemske primjene kortikosteroida započnu primjenjivati NASONEX sprej za nos.
English: NASONEX Nasal Spray demonstrated a clinically significant onset of action within 12 hours after the first dose in some patients with seasonal allergic rhinitis; however, full benefit of treatment may not be achieved in the first 48 hours.
Croatian: NASONEX sprej za nos pokazao je klinički značajan početak djelovanja unutar 12 sati nakon prve doze u nekih bolesnika sa sezonskim alergijskim rinitisom.
English: PHARMACEUTICAL FORM AND CONTENTS Nasal Spray Suspension
Croatian: OBLIK I SADRŽAJ Sprej za nos, suspenzija 60 uštrcaja
English: How to use Nasonex
Croatian: Kako primjenjivati lijek Nasonex
English: It is recommended that the height of children receiving prolonged treatment with nasal corticosteroids is regularly monitored.
Croatian: U djece koja dugotrajno primaju terapiju nazalnim kortikosteroidima preporučuje se redovito mjerenje visine.
English: Nasal Polyposis
Croatian: Nosna polipoza
English: In a placebo-controlled clinical trial in which paediatric patients (n=49/group) were administered NASONEX Nasal Spray 100 micrograms daily for one year, no reduction in growth velocity was observed.
Croatian: primjenjivali NASONEX sprej za nos 100 mikrograma na dan tijekom jedne godine, nije primijećeno smanjenje brzine rasta.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each metered actuation delivers 50 µg mometasone furoate.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna sprej doza sadrži 50 µg mometazonfuroata.
English: increase in pressure in the eye (glaucoma) and/or cataracts causing visual disturbances, damage to the partition in the nose which separates the nostrils changes in taste and smell difficulty in breathing and/or wheezing
Croatian: • povećanje očnog tlaka (glaukom) i/ili katarakte, uzrokujući poremećaj vida
English: Dose reduction is recommended following control of symptoms.
Croatian: Nakon stavljanja simptoma pod kontrolu, preporučuje se smanjenje doze.
English: Respiratory, thoracic and mediastinal disorders
Croatian: Poremećaji dišnog sustava, prsišta i sredoprsja epistaksa*
English: How to store Nasonex
Croatian: Kako čuvati lijek Nasonex
English: NASONEX Nasal Spray should not be used in the presence of untreated localised infection involving the nasal mucosa, such as herpes simplex.
Croatian: Preosjetljivost na djelatnu tvar, mometazonfuroat, ili neku od pomoćnih tvari navedenih u dijelu 6.1. NASONEX sprej za nos se ne smije koristiti kada postoji neliječena lokalizirana infekcija koja zahvaća sluznicu nosa, kao što je herpes simplex.
English: Cleaning your nasal spray
Croatian: Čišćenje spreja za nos
English: Nasal septum perforation
Croatian: Prijavljivanje nuspojava
English: Increased intraocular pressure
Croatian: Poremećaji oka glaukom povišeni intraokularni tlak katarakte
English: What Nasonex contains
Croatian: Sadržaj pakiranja i druge informacije Što Nasonex sadrži
English: METHOD AND ROUTE(S) OF ADMINISTRATION For nasal use.
Croatian: NAČIN I PUT(EVI) PRIMJENE LIJEKA
English: Contents of the pack and other information
Croatian: Kako čuvati lijek Nasonex Sadržaj pakiranja i druge informacije
English: Throat irritation*
Croatian: Poremećaji probavnog sustava iritacija grla*
English: PACKAGE LEAFLET
Croatian: mometazonfuroat
English: Polysorbate 80
Croatian: 4.8 Nuspojave
English: Hay fever and perennial rhinitis
Croatian: Peludna groznica i cjelogodišnji rinitis
English: [See Annex I - To be completed nationally] {Name and Address} <{tel}> <{fax}> <{e-mail}>
Croatian: {Ime i adresa} <{tel}> <{fax}> <{e-mail}>
English: You should wait until the infection is resolved before you start using the nasal spray.
Croatian: Ne smijete započeti s primjenom spreja za nos sve dok se ne riješi infekcija.
English: INSTRUCTIONS ON USE [To be completed nationally]
Croatian: 14. NAČIN IZDAVANJA LIJEKA [Ispunjava država članica]
English: Treatment of Hayfever and Perennial Rhinitis
Croatian: Drugi lijekovi i Nasonex
English: It has been used in medicines for several decades.
Croatian: Upotrebljava se u lijekovima već nekoliko desetljeća.
English: It is available as modified-release tablets (5 mg and 20 mg).
Croatian: Dostupan je u obliku tableta s prilagođenim oslobađanjem (5 mg i 20 mg).
English: Plenadren hydrocortisone
Croatian: Plenadren hidrokortizon
English: In situations of excessive physical or mental stress or illness, patients may need further doses of hydrocortisone.
Croatian: U situacijama prekomjernog fizičkog ili mentalnog stresa ili bolesti, bolesnicima će možda biti potrebne dodatne doze hidrokortizona.
English: Treatment may need to be individually adjusted according to how the patient responds.
Croatian: Liječenje će se možda trebati individualno prilagoditi, ovisno o odgovoru bolesnika.
English: What is Plenadren and what is it used for?
Croatian: Što je Plenadren i za što se koristi?
English: Symptoms include weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin.
Croatian: Simptomi uključuju gubitak tjelesne težine, slabost mišića, iscrpljenost, nizak krvni tlak, a ponekad i tamnjenje kože.
English: Other information about Plenadren
Croatian: Ostale informacije o lijeku Plenadren
English: The usual daily dose ranges from 20 to 30 mg, once per day early in the morning; tablets should be swallowed whole with a glass of water at least 30 minutes before food.
Croatian: Uobičajena dnevna doza iznosi od 20 do 30 mg jedanput dnevno i uzima se rano ujutro; tablete treba progutati cijele uz čašu vode, barem 30 minuta prije obroka.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Plenadren on 3 November 2011.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet koje je za lijek Plenadren na snazi u Europskoj uniji od 3. studenog 2011.
English: What measures are being taken to ensure the safe and effective use of Plenadren?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Plenadren?
English: Why is Plenadren approved?
Croatian: Zašto je lijek Plenadren odobren?
English: Plenadren can only be obtained with a prescription.
Croatian: Plenadren se izdaje samo na recept.
English: It is taken early in the morning to mimic the fact that in healthy people the blood level of cortisol increases early in the morning.
Croatian: Uzima se rano ujutro da bi oponašao stanje u zdravih ljudi pri kojem se razina kortizola u krvi povećava rano ujutro.
English: Adrenal insufficiency (including primary insufficiency or Addison's disease) is a condition where the adrenal glands (located just above the kidneys) do not produce enough of a steroid hormone called cortisol (also known as the stress hormone because it is released in response to stress).
Croatian: Adrenalna insuficijencija (uključujući primarnu insuficijenciju ili Addisonovu bolest) jest stanje u kojemu nadbubrežne žlijezde (koje se nalaze neposredno iznad bubrega) ne proizvode dovoljno steroidnog hormona kortizola (također poznatog kao hormon stresa jer se izlučuje kao odgovor organizma na stres).
English: This is a summary of the European public assessment report (EPAR) for Plenadren.
Croatian: Ovo je sažetak europskoga javnog izvješća o procjeni (EPAR) za lijek Plenadren.
English: The full EPAR for Plenadren can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Croatian: Cjeloviti EPAR za lijek Plenadren nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: What are the risks associated with Plenadren?
Croatian: Koji su rizici povezani s lijekom Plenadren?
English: Because the number of patients with adrenal insufficiency is low, the disease is considered ‘rare', and Plenadren was designated an ‘orphan medicine' (a medicine used in rare diseases) on 22 May 2006.
Croatian: Budući da je broj bolesnika s adrenalnom insuficijencijom nizak, dotična se bolest smatra „rijetkom” te je Plenadren dobio status „lijeka za liječenje rijetkih bolesti” 22. svibnja 2006.
English: The study looked at the levels of cortisol in the patients' blood during a 24-hour period following three months of treatment.
Croatian: Tijekom ispitivanja promatrane su razine kortizola u krvi bolesnika tijekom razdoblja od 24 sata nakon 3 mjeseca liječenja.
English: The summary of the opinion of the Committee for Orphan Medicinal Products for Plenadren can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/Rare disease designations.
Croatian: Sažetak mišljenja Odbora za lijekove za rijetke bolesti o lijeku Plenadren dostupan je na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/Rare disease designations.
English: The overall amount of cortisol absorbed into the blood was around 20% lower in patients taking Plenadren compared with patients taking conventional hydrocortisone treatment.
Croatian: Ukupna količina kortizola apsorbiranoga u krv bila je oko 20 % niža u bolesnika koji su uzimali Plenadren u usporedbi s bolesnicima u kojih je primijenjeno konvencionalno liječenje hidrokortizonom.
English: The most common side effects with Plenadren (seen in more than 1 patient in 10) are fatigue (tiredness), diarrhoea, vertigo (feeling dizzy) and headache.
Croatian: Najčešće nuspojave lijeka Plenadren (uočene u više od 1 na 10 osoba) jesu iscrpljenost (umor), proljev, vrtoglavica i glavobolja.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Plenadren have been included in the summary of product characteristics and the package leaflet.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Plenadren nalaze se u sažetku opisa svojstava lijeka i u uputi o lijeku.
English: This may be given as Plenadren tablets twice or three times daily or as conventional immediate-release tablets or injections, either alone or in combination with Plenadren.
Croatian: U tom slučaju bolesnicima se može dati Plenadren u obliku tableta dvaput ili triput dnevno, ili u obliku konvencionalnih tableta s trenutačnim otpuštanjem ili injekcije, same ili u kombinaciji s lijekom Plenadren.
English: Adrenal insufficiency can require life-long treatment to replace the missing cortisol.
Croatian: Adrenalna insuficijencija može zahtijevati doživotno liječenje kako bi se nadomjestio nedostatak kortizola.