FrancophonIA/ELRC3.0 huggingface dataset:
English: Figure 4 - Kaplan-Meier curves of progression-free survival in patients with metastatic gastric cancer
Danish: Figur 4 - Kaplan-Meier kurve for progressionsfri overlevelse hos patienter med metastatisk gastrisk cancer
English: Treatment must not be started if the absolute neutrophil count is < 1.5 ×109/L, if the platelet counts are < 75× 109/L, or if the patient has an unresolved Grade 3 or 4 non-haematological clinically relevant toxicity from prior therapies.
Danish: Behandling må ikke startes, hvis det absolutte neutrofiltal er < 1,5 ×10
English: Neurotoxicity Dysaesthesia Hyperaesthesia Hypoaesthesia Syncope
Danish: Dehydrering Hyperglykæmi Hyperkaliæmi Hypokaliæmi Hypofosfatæmi Hypernatriæmi Hyponatriæmi Hypokalcæmi Gigt
English: Following multiple doses of Lonsurf (35 mg/m2/dose twice daily) in patients with advanced solid tumours, the mean times to peak plasma concentrations (tmax) of trifluridine and tipiracil hydrochloride were around 2 hours and 3 hours, respectively.
Danish: /dosis to gange dagligt) hos patienter med fremskredne solide tumorer var de gennemsnitlige tider til maksimale plasmakoncentrationer (tmax) af trifluridin og tipiracilhydrochlorid omkring henholdsvis 2 timer og 3 timer.
English: • Moderate or severe hepatic impairment
Danish: • Moderat eller svært nedsat leverfunktion
English: Each film-coated tablet contains 20 mg trifluridine and 8.19 mg tipiracil (as hydrochloride).
Danish: Hver filmovertrukket tablet indeholder 20 mg trifluridin og 8,19 mg tipiracil (som hydrochlorid).
English: EU/1/16/1096/006 60 film-coated tablets
Danish: EU/1/16/1096/006 60 filmovertrukne tabletter
English: Trifluridine is a substrate of TPase, but is not metabolised by cytochrome P450 (CYP).
Danish: Trifluridin er substrat for TPase, men metaboliseres ikke af CYP.
English: Figure 3- Kaplan-Meier curves of overall survival in patients with metastatic gastric cancer
Danish: Figur 3- Kaplan-Meier kurve for samlet overlevelse hos patienter med metastatisk gastrisk cancer
English: Biliary tract infection Influenza
Danish: Infektiøs enteritis Lungeinfektion Infektion i galdevejene Influenza
English: Lonsurf 20 mg/8.19 mg film-coated tablets
Danish: Lonsurf 20 mg/8,19 mg filmovertrukne tabletter
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 15 mg trifluridine and 6.14 mg of tipiracil (as hydrochloride).
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver filmovertrukket tablet indeholder 15 mg trifluridin og 6,14 mg tipiracil (som hydrochlorid).
English: • Pulmonary embolism (uncommon): blood clots in lungs.
Danish: • Blodpropper i lungerne (ikke almindelig): Symptomerne inkluderer kortåndethed og smerter i brystet eller i benene.
English: Gingival bleeding Glossitis
Danish: Gingivalblødning Glossitis
English: EU/1/16/1096/005 40 film-coated tablets
Danish: EU/1/16/1096/005 40 filmovertrukne tabletter
English: If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Danish: Hvis du er i tvivl, så spørg lægen eller apotekspersonalet.
English: NAME OF THE MEDICINAL PRODUCT Lonsurf 20 mg/8.19 mg tablets trifluridine/tipiracil
Danish: LÆGEMIDLETS NAVN Lonsurf 20 mg/8,19 mg tabletter trifluridin/tipiracil
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each film-coated tablet contains 20 mg trifluridine and 8.19 mg of tipiracil (as hydrochloride).
Danish: ANGIVELSE AF AKTIVT STOF/AKTIVE STOFFER Hver filmovertrukket tablet indeholder 20 mg trifluridin og 8,19 mg tipiracil (som hydrochlorid).
English: NAME OF THE MEDICINAL PRODUCT Lonsurf 15 mg/6.14 mg tablets trifluridine/tipiracil
Danish: LÆGEMIDLETS NAVN Lonsurf 15 mg/6,14 mg tabletter trifluridin/tipiracil
English: There is no need for a starting dose adjustment in patients with mild hepatic impairment (see section
Danish: Det er ikke nødvendigt at justere startdosis hos patienter med let nedsat leverfunktion (se pkt.
English: Titanium dioxide (E171) Magnesium stearate
Danish: Titandioxid (E171)
English: a Kaplan-Meier estimates b Methodology of Brookmeyer and Crowley c Stratified log-rank test (strata: KRAS status, time since diagnosis of first metastasis, region)
Danish: Stratificeret log-rank test (strata: KRAS-status, tid siden diagnosticering af første metastase, region) Figur 1- Kaplan-Meier kurve for samlet overlevelse hos patienter med metastatisk kolerektal cancer
English: Marketing Authorisation Holder Les Laboratoires Servier 50 rue Carnot
Danish: 50 rue Carnot
English: • CTCAE* Grade 4 neutropenia (< 0.5 x 109/L) or thrombocytopenia (< 25 × 109/L) that results in more than 1 week's delay in start of next cycle
Danish: • CTCAE* grad 4 neutropeni (< 0,5 x 10
English: The median time to PS ≥ 2 for the Lonsurf group and placebo group was 5.7 months and 4.0 months, respectively, with a hazard ratio of 0.66 (95% CI: [0.56, 0.78]), p < 0.0001.
Danish: Behandling med Lonsurf plus BSC resulterede i en statistisk signifikant forlængelse af tiden med ECOG-PS < 2 sammenlignet med placebo plus BSC. Mediantiden til PS ≥ 2 for Lonsurf-gruppen og placebo-gruppen var henholdsvis 5,7 måneder og 4,0 måneder med en hazard ratio på 0,66 (95 % CI: [0,56, 0,78]), p < 0,0001.
English: Following a single dose of Lonsurf (35 mg/m2) in patients with advanced solid tumours, the mean times to peak plasma concentrations (tmax) of trifluridine and tipiracil hydrochloride were around 2 hours and 3 hours, respectively.
Danish: 2) til patienter med fremskredne solide tumorer var de Efter en enkelt dosis af Lonsurf (35 mg/m gennemsnitlige tider til maksimale plasmakoncentrationer (tmax) af trifluridin og tipiracilhydrochlorid omkring henholdsvis 2 timer og 3 timer.
English: Discomfort
Danish: Ubehag
English: NAME OF THE MEDICINAL PRODUCT Lonsurf 15 mg/6.14 mg film-coated tablets Lonsurf 20 mg/8.19 mg film-coated tablets
Danish: Lonsurf 15 mg/6,14 mg filmovertrukne tabletter Lonsurf 20 mg/8,19 mg filmovertrukne tabletter
English: Candida infection Bacterial infection Infection
Danish: Herpes zoster Tinea pedis Candida infektion Bakteriel infektion Infektion
English: NAME OF THE MEDICINAL PRODUCT Lonsurf 15 mg/6.14 mg film-coated tablets trifluridine/tipiracil
Danish: LÆGEMIDLETS NAVN Lonsurf 15 mg/6,14 mg filmovertrukne tabletter trifluridin/tipiracil
English: NAME OF THE MEDICINAL PRODUCT Lonsurf 20 mg/8.19 mg film-coated tablets trifluridine/tipiracil
Danish: LÆGEMIDLETS NAVN Lonsurf 20 mg/8,19 mg filmovertrukne tabletter trifluridin/tipiracil
English: Resumption criteriaa
Danish: Kriterie for doseringsgenoptagelse a
English: No adjustment of the starting dose is recommended in patients with mild or moderate renal impairment (see sections 4.4 and 5.2).
Danish: Det er ikke nødvendigt at justere startdosis hos patienter med let eller moderat nedsat nyrefunktion (se pkt.
English: België/Belgique/Belgien
Danish: België/Belgique/Belgien S.A. Servier Benelux N.V.
English: Diarrhoea Nausea Vomiting
Danish: Mave-tarm-kanalen Diarré Kvalme
English: Renal failure Cystitis noninfective Micturition disorder Haematuria Leukocyturia
Danish: Ikke-infektiøs cystitis Vandladningsforstyrrelser Hæmaturi
English: mild (CrCl = 60 to 89 mL/min) or moderate (CrCl = 30 to 59 mL/min) renal impairment subgroups.
Danish: Den globale bivirkningsforekomst er den samme hos undergrupper med normal nyrefunktion (CrCl ≥ 90 ml/min), let nedsat nyrefunktion (CrCl = 60-89 ml/min) eller moderat nedsat nyrefunktion (CrCl = 30-59 ml/min).
English: • bloating, passing gas, indigestion
Danish: • oppustethed, luft fra tarmen, fordøjelsesbesvær
English: Hyponatraemia
Danish: Hyperæstesi
English: What you need to know before you take Lonsurf 3.
Danish: Det skal du vide, før du begynder at tage Lonsurf Sådan skal du tage Lonsurf Bivirkninger
English: Blood alkaline phosphatase increased Weight decreased
Danish: Forhøjede leverenzymer Forhøjet alkalisk fosfatase
English: • feeling dizzy, headache
Danish: • svimmelhed, hovedpine
English: Titanium dioxide (E171) Iron oxide red (E172) Magnesium stearate
Danish: Hypromellose Macrogol (8000) Titandioxid (E171) Magnesiumstearat
English: Blood urea increased
Danish: Forhøjet blod-urinstof
English: Cancer pain
Danish: Cancersmerter
English: • Severe renal impairment (CrCl below 30 mL/min) or end stage renal disease Administration is not recommended in patients with severe renal impairment or end stage renal disease as there are no data available for these patients (see section 4.4).
Danish: Administration anbefales ikke til patienter med svært nedsat nyrefunktion eller med terminal nyresygdom, da er ikke foreligger data for denne patientgruppe (se pkt.
English: Herpes zoster
Danish: Magnesiumstearat
English: Overall Survival
Danish: Sandsynlighed for overlevelse
English: Hypocalcaemia
Danish: Hypromellose
English: • Lonsurf 15 mg/6.14 mg is a white, biconvex, round, film-coated tablet, printed with “15” on one side and “102” and “15 mg” on the other side in grey ink.
Danish: • Lonsurf 15mg/6,14 mg mg er en hvid, bikonveks, rund, filmovertrukket tablet, præget med “15”
English: What Lonsurf looks like and contents of the pack
Danish: Udseende og pakningsstørrelser
English: • rash, itchy or flaky skin
Danish: • udslæt, kløende eller skællet hud
English: Hypokalaemia
Danish: Hypæstesi
English: Oesophagitis
Danish: Carnaubavoks
English: Reflux gastritis
Danish: Refluksgastritis
English: Hypernatraemia
Danish: Lactosemonohydrat
English: • feeling generally out of sorts (malaise)
Danish: • generel følelse af utilpashed
English: Gout
Danish: Amning
English: • liver disorder
Danish: • væskemangel
English: 15 mg/6.14 mg 20 mg/8.19 mg Level 1 dose reduction: From 35 mg/m2 to 30 mg/m2 30 mg/m2
Danish: Niveau 1-dosisreduktion: Fra 35 mg/m til 30 mg/m
English: Flatulence
Danish: Artralgi
English: Bone pain
Danish: Ελλάδα
English: Lower respiratory tract infection
Danish: Nedre luftvejsinfektion Septisk shock b
English: Maximum efficacy is achieved within 48 hours.
Danish: Den maksimale virkningsgrad opnås inden for 48 timer.
English: Both components were still measurable in the hair 56 days following treatment.
Danish: Begge stoffer var stadig målelige i hår 56 dage efter behandlingen.
English: Do not use after the expiry date stated on the carton after “EXP”.
Danish: Må ikke anvendes efter den udløbsdato, som er angivet på æsken efter ”EXP”.
English: These signs are transient and reversible if prompt and appropriate treatment is administered.
Danish: Disse symptomer er forbigående og reversible, hvis der gives omgående og hensigtsmæssig behandling.
English: Recently treated animals should not be allowed to sleep with the owners, especially children.
Danish: Dyr, som er behandlet for nylig, må ikke sove sammen med deres ejere, især ikke sammen med børn.
English: The veterinary medicinal product should not enter watercourses, as this may be dangerous for fish and other aquatic organisms.
Danish: Dette veterinærlægemiddel må ikke udledes i vandløb, da dette kan være farligt for fisk og andre organismer i vandet.
English: If pemphigus-like signs occur, further use of the product should be avoided.
Danish: Hvis der forekommer pemphigus-lignende symptomer, bør fortsat anvendelse af produktet undgås.
English: In these cases do not treat more frequently than once a fortnight.
Danish: I disse tilfælde behandles ikke hyppigere end hver 14. dag.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Active substances
Danish: KVALITATIV OG KVANTITATIV SAMMENSÆTNING Aktive stoffer:
English: Where possible, treatment should not be discontinued until skin scrapings are negative on at least two monthly occasions.
Danish: Behandlingen bør så vidt muligt fortsættes, indtil hudskrab er negative i mindst 2 måneder.
English: Care should be taken to ensure that the content of the pipette or the applied dose does not come into contact with the eyes or mouth of the recipient and/or other animals.
Danish: Der bør udvises omhyggelighed for at sikre, at indholdet i pipetten eller den afgivne dosis ikke kommer i kontakt med øjnene eller munden på hunden og/eller andre dyr.
English: No adverse effects were observed in healthy dogs and puppies aged 8 weeks and older treated 7 times at two-week intervals with 3-5 times the recommended dose.
Danish: Der er ikke observeret bivirkninger hos raske hunde og 8 uger gamle hvalpe, der blev behandlet 7 gange hver 14. dag med 3-5 gange den anbefalede dosis.
English: The following table defines the size of pipette to be used according to the weight of the dog.
Danish: Følgende tabel angiver den pipettestørrelse, der skal anvendes i overensstemmelse med hunden vægt.
English: Maximum concentrations in the hair were generally reached between 2 to 7 days post treatment and gradually declined through 56 days post treatment.
Danish: Maksimumkoncentrationer i hår blev generelt nået 2-7 dage efter behandlingen og mindskedes gradvist i løbet af 56 dage efter behandlingen.
English: Do not administer to sick or debilitated dogs or dogs suffering from heat stress.
Danish: Må ikke anvendes til syge eller svækkede hunde eller hunde, der er varmepåvirkede.
English: The risk of experiencing adverse effects may however increase when overdosing, so animals should always be treated with the correct pipette size according to body weight.
Danish: Risikoen for bivirkninger kan dog øges ved overdosering, så derfor bør dyr altid behandles med den korrekte størrelse pipette i forhold til deres legemsvægt.
English: Weight Range of Dog (kg)
Danish: Hundens vægtklasse (kg)
English: It is important to apply the dose to an area where the animal cannot lick it off and to make sure that animals do not lick each other following treatment.
Danish: Det er vigtigt, at præparatet påføres et område, hvor dyret ikke kan slikke det af, og at dyr ikke slikker hinanden efter behandlingen.
English: Shelf life of the veterinary medicinal product as package for sale:2 years.
Danish: Opbevaringstid for veterinærlægemidlet i salgspakning: 2 år.
English: As demodicosis is a multi-factorial disease, where possible, it is advisable to also treat any underlying disease appropriately.
Danish: Eftersom demodicose er en multifaktor-sygdom, tilrådes det desuden at behandle den eventuelle underliggende sygdom, så vidt det er muligt.
English: In cases of frequent water exposure the duration of activity may be reduced.
Danish: Ved hyppig kontakt med vand kan virkningsvarigheden nedsættes.
English: Pfizer Limited Ramsgate Road Sandwich Kent CT13 9NJ United Kingdom
Danish: Pfizer Limited Ramsgate Road Sandwich Kent CT13 9NJ Storbritannien
English: Remove the pipette from the package.
Danish: Tag en pipette ud af pakningen.
English: In rare cases, transient irritation may occur at the site of product application.
Danish: Der kan i sjældne tilfælde opstå forbigående irritation på applikationsstedet.
English: Pharmacotherapeutic group: Ectoparasiticides for topical use, ATC Vet Code QP 53AD51
Danish: Farmakoterapeutisk gruppe: Ectoparasiticider til udvortes brug, ATCvet-kode:QP 53AD51
English: Children should not have access to used pipettes.
Danish: Børn bør ikke have adgang til brugte pipetter.
English: Dogs should be prevented from accessing streams and rivers for the 24-hour period following treatment.
Danish: Hunde bør ikke svømme i vandløb og floder 24 timer efter behandlingen.
English: Metaflumizone is an insecticide belonging to the semicarbazone group of compounds.
Danish: Metaflumizon er et insecticid, der tilhører gruppen af semicarbazon-forbindelser.
English: This is normal and will generally resolve within a few days after administration, though may persist longer on rare occasions.
Danish: Dette er normalt og vil sædvanligvis forsvinde inden for få dage efter behandlingen, men kan i sjældne tilfælde vare i længere tid.
English: This product may cause skin sensitisation and allergic reactions in humans.
Danish: Præparatet kan forårsage øget følsomhed af huden og allergiske reaktioner hos mennesker.
English: Children should not have contact with the product or with animals during treatment.
Danish: Børn bør ikke være i kontakt med præparatet eller med dyret under behandlingen.
English: The use of protective gloves while handling the product is recommended.
Danish: Det anbefales at anvende beskyttelseshandsker ved håndtering af præparatet.
English: The veterinary medicinal product is packaged in individual-dose transparent plastic pipettes over packed in an aluminium foil package.
Danish: Dette veterinærlægemiddel er pakket i gennemsigtige enkeltdosispipetter i en aluminiumsfoliepakning.
English: For treatment of biting lice a single dose should be sufficient.
Danish: En enkelt dosis til behandling af udklækkede lus er tilstrækkelig.
English: This product may cause mild eye irritation.
Danish: Præparatet kan forårsage lettere irritation af øjnene.
English: This product should not be administered by children.
Danish: Dette lægemiddel må ikke administreres af børn.
English: Amitraz is a formamidine acaricide.
Danish: Amitraz er et formamidin-acaricid.
English: To minimise the potential for inhalation, it is recommended that the product is applied in open air or in well ventilated rooms.
Danish: For at minimere risikoen for indånding anbefales det at påføre produktet udendørs eller i et ventileret værelse.
English: *Due to limited space on the packaging, the abbreviations "S", "M", "M/L", "L" and "XL", which represent "small", “medium”,” medium/large”, “large” and “extra large”, respectively, are used on the blister foil and applicator pipettes.
Danish: *På grund af begrænset plads på mærkningen, anvendes forkortelser ”S”, ”M”, ”M/L”, ”L” og ”XL”, som forestiller respektive ”lille”, ”mellemstor”, ”mellemstor-stor”, ”stor” og ”ekstra stor”, på blisterkortene og pipetterne.
English: Stored pipettes must be kept in the intact foil package.
Danish: Pipetterne skal opbevares i en intakt foliepakning.
English: This is not a sign of intoxication and disappears within minutes without treatment.
Danish: Dette er ikke et tegn på forgiftning og det vil forsvinde uden behandling efter få minutter.
English: and lice (Trichodectes canis) in dogs.
Danish: og lus (Trichodectes canis) hos hunde.
English: Do not allow puppies to lick the application site of their mothers when it is still wet.
Danish: Hvalpe må ikke slikke moderen på påføringsstedet, mens det stadig er vådt.
English: CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE
Danish: B. BETINGELSER ELLER BEGRÆNSNINGER VEDRØRENDE UDLEVERING OG BRUG
English: In very rare cases, pemphigus foliaceous-like cutaneous signs have been reported.
Danish: Der er i meget sjældne tilfælde rapporteret pemphigusfoliaceus-lignende hudsymptomer.
English: It acts at octopamine receptor sites in ectoparasites giving rise to increased nervous activity and death of insects.
Danish: Det virker på octopamin-receptor-bindingssteder hos ektoparasitter og medfører øget nerveaktivitet og død hos insekterne.
English: STATEMENT OF THE ACTIVE SUBSTANCE AND OTHER INGREDIENTS Active substances
Danish: ANGIVELSE AF DE(T) AKTIVE STOF(FER) OG ANDRE INDHOLDSSTOFFER Aktivstoffer
English: Most lice are killed within 7 days.
Danish: Størstedelen af lusene dør inden for 7 dage.
English: Treatment with other products containing amitraz is not recommended whilst the dog is being treated with ProMeris Duo Spot-On for Dogs.
Danish: Behandling med andre præparater, der indeholder amitraz, frarådes, imens hunden behandles med ProMeris Duo, spot-on opløsning til hunde.
English: ProMeris Duo contains components that, on very rare occasions, can cause respiratory irritation in certain people.
Danish: ProMeris Duo indeholder stoffer, som i meget sjældne tilfælde kan forårsage åndedrætsbesvær hos enkelte personer.
English: For treatment of demodicosis, the product should be administered at monthly intervals until clinical signs resolve.
Danish: Ved behandling af demodicose skal lægemidlet administreres hver 4. uge, indtil de kliniske symptomer er forsvundet.
English: If symptoms are severe or persist the alpha-2-adreno-receptor antagonist atipamezole hydrochloride may be used at a dose of 0.2 mg/kg bodyweight by intramuscular injection to reverse these side-effects.
Danish: Hvis bivirkningerne er alvorlige eller vedholdende, kan alpha-2-adrenoreceptor antagonisten, atipamexolhydrochlorid, anvendes med en dosis på 0,2 mg/kg legemsvægt ved intramuskulær injektion for at fjerne disse bivirkninger.
English: This product contains amitraz, which can lead to adverse neurological effects in humans and especially in children.
Danish: Dette lægemiddel indeholder amitraz, der forårsager neurologiske bivirkninger hos mennesker og især hos børn.
English: If the product accidentally gets into eyes, they should be thoroughly flushed with water.
Danish: Hvis præparatet ved et uheld kommer i øjnene, skylles de grundigt med vand.
English: Most of these signs are due to alpha-2adreno-receptor agonist effects.
Danish: Størstedelen af disse bivirkninger skyldes alpha-2-adrenoreceptor-agonist-effekter.
English: The veterinary medicinal product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
Danish: Præparatet kan anvendes som en del af behandlingsstrategien ved loppebetinget allergisk dermatit.
English: Kills most ticks within 48 hours.
Danish: Størstedelen af flåterne dør inden for 48 timer.
English: After topical administration at a single site at the base of the skull, both metaflumizone and amitraz were rapidly distributed throughout the surface of the skin.
Danish: Efter topikal administration på et enkelt sted på huden i nakken blev både metaflumizon og amitraz fordelt hurtigt på huden.
English: However, prolonged, intense exposure to water should be avoided.
Danish: Langvarig kontakt med vand bør imidlertid undgås.
English: If the dog requires shampooing, it is better to do so before applying the veterinary medicinal product.
Danish: Hvis det er nødvendigt at vaske hunden med shampoo, bør dette gøres før behandling med præparatet.
English: Dogs over 8 weeks of age
Danish: Hunde over 8 uger.
English: The veterinary medicinal product will prevent flea infestation for up to 6 weeks and tick infestation for 4 weeks following a single administration.
Danish: Én behandling med dette veterinære lægemiddel vil forebygge loppeangreb i op til 6 uger og flåtangreb i 4 uger.
English: The solvent in ProMeris Duo may stain certain materials including leather, fabrics, plastics and finished surfaces.
Danish: Opløsningsmidlet i ProMeris Duo kan misfarve materialer inklusive læder, stof, plastic og overflader.
English: After topical administration at a single site at the base of the skull, both metaflumizone and amitraz levels in plasma were too low to allow the calculation of standard pharmacokinetic parameters.
Danish: Efter topikal administration på et enkelt sted i nakken var plasmaniveauet for både metaflumizon og amitraz for lavt til at kunne udregne almindeligt anvendte farmakokinetiske parametre.
English: Signs are usually transitory and generally resolved without treatment within 24 hours.
Danish: Bivirkningerne er sædvanligvis kortvarige og vil normalt forsvinde uden behandling inden for 24 timer.
English: For dogs more than 50 kg, use a combination of two pipettes that most closely matches the body weight.
Danish: Til hunde på over 50 kg bruges en passende kombination af pipetter.
English: Do not administer to cats.
Danish: Må ikke anvendes til katte.
English: TARGET SPECIES For dogs over 8 weeks of age.
Danish: DYREARTER Til hunde over 8 uger.
English: The recommended minimum dose is 20 mg/kg bodyweight for each of metaflumizone and amitraz, equivalent to 0.133ml/kg bodyweight.
Danish: Anbefalet minimumsdosis af metaflumizon og amitraz er 20 mg/kg legemsvægt svarende til 0,133 ml/kg legemsvægt.
English: Children should not be allowed to have contact with treated animals until the application site is dry.
Danish: Børn bør ikke være i direkte kontakt med behandlede dyr, før påføringsstedet er tørt.
English: Known side-effects of amitraz and metabolites are sedation, lethargy, CNS depression, hyperglycaemia, bradycardia and slow, shallow breathing.
Danish: Kendte bivirkninger ved brug af amitraz og dens metabolitter er sedation, letargi, CNS-depression, hyperglykæmi, bradykarid og langsom, overfladisk vejrtrækning.