FrancophonIA/ELRC3.0 huggingface dataset:
English: Further information on the HMPC assessment of chicory root medicines, including details of the Committee's conclusions, can be found under the tab ‘All documents' on the Agency's website: ema.europa.eu/Find medicine/Herbal medicines for human use.
Estonian: Lisateave sigurijuurt sisaldava ravimi hinnangu kohta, sh komitee kokkuvõtte detailne kirjeldus, on Euroopa Ravimiameti veebilehe jaotises „All documents”: ema.europa.eu/Find medicine/Herbal medicines for human use.
English: Other information about chicory root medicines
Estonian: Muu teave sigurijuurt sisaldava ravimi kohta
English: The HMPC concluded that, on the basis of its long-standing use, chicory root can be used for the relief of symptoms of mild digestive disorders (such as feeling full, flatulence and slow digestion) and temporary loss of appetite.
Estonian: Taimsete ravimite komitee järeldas, et lähtudes sigurijuure pikaajalisest kasutamisest, võib seda kasutada kergete seedehäirete (nagu täiskõhutunne, kõhupuhitus ja aeglane seedimine) sümptomite leevendamiseks ja ajutise isukaotuse korral.
English: Any applications for the licensing of medicines containing chicory root have to be submitted to the national authorities responsible for medicinal products, which will assess the application for the herbal medicine and take into account the scientific conclusions of the HMPC.
Estonian: Sigurijuurt sisaldava ravimi müügiloa taotlus tuleb esitada riiklikule ravimiametile, mis hindab taimse ravimi müügiloa taotlust, võttes arvesse taimsete ravimite komitee teaduslike järelduste kokkuvõtet.
English: Chicory root preparations are obtained by comminuting the roots (reducing them into tiny pieces).
Estonian: Sigurijuure tooteid saadakse juuri peenestades (väikesteks tükkideks lõigates).
English: The HMPC conclusions are taken into account by EU Member States when evaluating applications for the licensing of herbal medicines containing chicory root.
Estonian: ELi liikmesriigid võtavad taimsete ravimite komitee järeldusi arvesse, kui nad hindavad sigurijuurt sisaldavate taimsete ravimite müügilubade taotlusi.
English: The HMPC conclusions on the use of chicory root medicines for the relief of symptoms of mild digestive disorders and temporary loss of appetite are based on their ‘traditional use'.
Estonian: Taimsete ravimite komitee järeldused sigurijuurt sisaldavate ravimite kasutamise kohta kergete seedehäirete ja ajutise isukaotuse sümptomite leevendamiseks põhinevad ravimite traditsioonilisel kasutamisel.
English: What evidence supports the use of chicory root medicines?
Estonian: Millised tõendid toetavad sigurijuurt sisaldava ravimi kasutamist?
English: At the time of the HMPC assessment, no side effects had been reported with these medicines.
Estonian: Taimsete ravimite komitee hinnanguraporti koostamise ajal ei esinenud teateid ravimi kõrvaltoimete kohta.
English: What is chicory root?
Estonian: Mis on sigurijuur?
English: This is a summary of the scientific conclusions reached by the Committee on Herbal Medicinal Products (HMPC) on the medicinal uses of chicory root.
Estonian: See on taimsete ravimite komitee teaduslike järelduste kokkuvõte, mis käsitleb sigurijuure meditsiinilisi kasutusviise.
English: What are the risks associated with chicory root medicines?
Estonian: Mis riskid kaasnevad sigurijuurt sisaldava ravimiga?
English: For more information about treatment with chicory root medicines, read the package leaflet that comes with the medicine or contact your doctor or pharmacist.
Estonian: Kui vajate lisateavet sigurijuurt sisaldava ravimi kasutamise kohta, lugege palun pakendi infolehte või pöörduge oma arsti või apteekri poole.
English: For practical information about using chicory root medicines, patients should read the package leaflet that comes with the medicine or contact their doctor or pharmacist.
Estonian: Kui vajate sigurijuurt sisaldava ravimi kasutamise kohta praktilisi nõuandeid, lugege ravimi pakendi infolehte või pöörduge oma arsti või apteekri poole.
English: How are chicory root medicines approved in the EU?
Estonian: Kuidas antakse Euroopa Liidus sigurijuurt sisaldavale ravimile müügiluba?
English: Detailed instruction on how to take chicory root medicines and who can use them can be found in the package leaflet that comes with the medicine.
Estonian: Täpsed juhised sigurijuurt sisaldavate ravimite kasutamise kohta on kirjas ravimipakendi infolehes.
English: Information on the use and licensing of chicory root medicines in EU Member States should be obtained from the relevant national authorities.
Estonian: ELi liikmesriikides saab teavet sigurijuurt sisaldava ravimi kasutamise ja müügiloa kohta riiklikult ravimiametilt.
English: In its assessment, the HMPC took into account the well documented use of chicory root in digestive disorders and loss of appetite.
Estonian: Oma hinnangus võttis taimsete ravimite komitee arvesse ka sigurijuure hästi dokumenteeritud kasutamist nende näidustuste korral.
English: This summary is not intended to provide practical advice on how to use medicines containing chicory root.
Estonian: Kokkuvõttes ei anta sigurijuurt sisaldava ravimi kasutamise kohta praktilisi nõuandeid.
English: Chicory root is the common name for the root of the plant Cichorium intybus L. The plant is cultivated or gathered to obtain the root for medicinal use.
Estonian: Sigurijuur on taime Cichorium intybus L. (harilik sigur) juure üldnimetus.
English: Chicory root can also be found in combination with other herbal substances in some herbal medicines.
Estonian: Sigurijuurt sisaldavad ravimid on tavaliselt saadaval taimeteena joomiseks Sigurijuurt leidub mõnedes taimsetes ravimites ka segatuna teiste taimsete ainetega.
English: Committee on Herbal Medicinal Products (HMPC)
Estonian: EMA/HMPC/286842/2013 Taimsete ravimite komitee (HMPC)
English: 15 months
Estonian: 15 kuud
English: You should take your medicine at the same time each day.
Estonian: Te peate võtma oma ravimit iga päev samal kellaajal.
English: It may be given with or without food.
Estonian: Manustada võib koos toiduga või ilma.
English: (See section 4.8.)
Estonian: (Vt lõik 4.8).
English: Very rare, not known
Estonian: Väga harv, teadmata
English: In addition, clinical tolerance was good in all patients.
Estonian: Lisaks oli kliiniline taluvus hea kõigil patsientidel.
English: It is preferable not to take this medicine during first and second trimesters of pregnancy.
Estonian: On soovitatav seda ravimit mitte võtta raseduse esimesel ja teisel trimestril.
English: If you have had a heart attack, it should be prescribed for at least four weeks.
Estonian: Kui teil on olnud südameatakk, määratakse ravi vähemalt neljaks nädalaks.
English: • if you are in your last trimester of pregnancy.
Estonian: • kui teie rasedus on viimases trimestris.
English: The absolute risk for cardiovascular malformation was increased from less than 1%, up to approximately 1.5%.
Estonian: Kardiovaskulaarse väärarengu absoluutne risk suurenes tasemelt alla 1% tasemele ligikaudu 1,5%.
English: • Third trimester of pregnancy (see section 4.6).
Estonian: • Raseduse kolmandal trimestril (vt lõik 4.6).
English: Contact your doctor immediately if you experience:
Estonian: Võtke kohe ühendust oma arstiga, kui teil on:
English: Thus, the results from this subset are in line with the overall trial results.
Estonian: Seega on selle alarühma tulemused kooskõlas uuringu üldiste tulemustega.
English: • Your doctor may order blood tests.
Estonian: • teie arst võib määrata vereanalüüse.
English: For further information please refer to section 5.1.
Estonian: Täiendav informatsioon vt lõik 5.1.
English: McDermott Laboratories Limited trading as Gerard Laboratories trading as Mylan Dublin, 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13, Ireland.
Estonian: McDermott Laboratories Limited trading as Gerard Laboratories trading as Mylan Dublin, 35/36 Baldoyle Industrial Estate, Grange Road, Dublin 13, Iirimaa.
English: In addition, your doctor may identify changes in your blood or urine tests.
Estonian: Lisaks võib teie arst täheldada muutusi teie vere- või uriiniproovis.
English: Rhone 69800, France
Estonian: Rhone 69800
English: The patient population included 19.7% women and 29.2% patients ≥65 years.
Estonian: Patsiendipopulatsioonis oli 19,7% naisi ja 29,2% ≥65-aastaseid.
English: In addition to clinical studies experience, adverse reactions have been spontaneously reported.
Estonian: Lisaks kliiniliste uuringute kogemusele on kõrvaltoimetest teatatud spontaanselt.
English: Given that children, infants and toddlers are often only seen at a late stage of intoxication, they will usually have already reached the acidosis stage.
Estonian: Et lapsi, imikuid ja väikelapsi nähakse sageli alles intoksikatsiooni hilisstaadiumis, on nad tavaliselt juba jõudnud atsidoosi faasi.
English: Initial hyperventilation leads to respiratory alkalosis.
Estonian: Algne hüperventilatsioon põhjustab respiratoorse alkaloosi.
English: Cytochrome P450 2C19 (CYP2C19)
Estonian: Tsütokroom P4502C19 (CYP2C19)
English: Do not use this medicine after the expiry date which is stated on the carton, blister and on the bottle after EXP.
Estonian: Ärge kasutage seda ravimit pärast kõlblikkusaega, mis on märgitud karbil, blistril ja pudelil pärast „EXP“.
English: 117 Allée des Parcs, 69 800 Saint Priest, France
Estonian: 117 Allée des Parcs, 69 800 Saint Priest, Prantsusmaa
English: Clinical trial data support use up to 12 months, and the maximum benefit was seen at 3 months (see section 5.1).
Estonian: Kliiniliste uuringute andmed toetavad kasutamist kuni 12 kuud ja maksimaalset efekti täheldati 3. kuul (vt lõik 5.1).
English: In any case, you should take it for as long as your doctor continues to prescribe it.
Estonian: Igal juhul peate te ravimit võtma senikaua, kuni arst seda teile määrab.
English: An occasional use of ASA (no more than 1,000 mg in any 24-hour period) should generally not cause a problem, but prolonged use of ASA in other circumstances should be discussed with your doctor or pharmacist.
Estonian: ASH juhupärane kasutamine (vähem kui 1000 mg mistahes 24-tunnise perioodi jooksul) ei tohiks üldiselt probleeme tekitada, kuid pikemaajaliseks kasutamiseks teistel asjaoludel peab oma arsti või apteekriga nõu pidama.
English: ** Information related to clopidogrel with frequency “not known”.
Estonian: ** Klopidogreeliga seotud teave, esinemissagedus „teadmata“.
English: • if you have a history of asthma or allergic reactions including allergy to any medicine used to treat your disease.
Estonian: • kui teil on astma või on olnud allergilisi reaktsioone, sh allergia teie raviks kasutatud mis tahes ravimi suhtes;
English: The risk is believed to increase with dose and duration of therapy.
Estonian: Usutavasti tõuseb risk koos annuse ja ravi kestusega.
English: Tenofovir
Estonian: Tenofoviir
English: Posology Adults and elderly
Estonian: Annustamine Täiskasvanud ja eakad
English: The binding is non-saturable in vitro over a wide concentration range.
Estonian: Seondumine on in vitro mitte-küllastuv laias kontsentratsioonivahemikus.
English: In addition, due to the presence of ASA, its use is also contraindicated in:
Estonian: ASH sisalduse tõttu on selle kasutamine lisaks vastunäidustatud:
English: • opioids: while you are treated with clopidogrel, you should inform your doctor before being prescribed any opioids treatment.
Estonian: • opioide; ravi ajal klopidogreeliga peate teavitama oma arsti enne teile mis tahes opioidiga ravi määramist.
English: • If you cut or injure yourself, it may take longer than usual for bleeding to stop.
Estonian: • kui te lõikate endale sisse või vigastate ennast, võib veritsuse seiskumiseks kuluda tavalisest rohkem aega.
English: • if you have gout.
Estonian: • kui teil on podagra;
English: In CURE, 823 (6.6%) patients received concomitant GPIIb/IIIa receptor antagonist therapy.
Estonian: CURE uuringus said 823 (6,6%) patsienti samaaegselt raviks ka GPIIb/IIIa retseptorite antagoniste.
English: Reproduction toxicity data show that ASA is teratogenic in several laboratory animals.
Estonian: Reproduktsioonitoksilisuse andmed näitavad ASH teratogeensust mitmetel laboriloomadel.
English: Platelets are very small structures in the blood which clump together during blood clotting.
Estonian: Trombotsüüdid on väga väikesed vere vormelemendid, mis vere hüübimise käigus kokku kleepuvad.
English: Depression of the nervous system can lead to coma, cardiovascular collapse and respiratory arrest.
Estonian: Närvisüsteemi pidurdamine võib viia koomani, kardiovaskulaarse kollapsi ja hingamise seiskumiseni.
English: • In children under 18 years of age, there is a possible association between ASA and Reye's syndrome.
Estonian: • Lastel vanuses kuni 18 aastat on võimalik seos ASH ja Reye sündroomi tekke vahel.
English: Contains lactose and Allura Red AC. See leaflet for further information.
Estonian: Sisaldab laktoosi ja Allura red AC-d. Lisateavet lugege pakendi infolehest.
English: Low doses (up to 100 mg/day):
Estonian: Väikesed annused (kuni 100 mg/päevas):
English: Following toxic doses (10-20 g), the plasma half-life may be increased to over 20 hours.
Estonian: Toksilise annuse (10...20 g) korral võib poolväärtusaeg vereplasmas pikeneda üle 20 tunni.
English: Clopidogrel:
Estonian: Klopidogreel:
English: The desiccant should not be eaten.
Estonian: Kuivatusainet ei tohi süüa.
English: Mylan Hungary Kft, H-2900 Komárom, Mylan utca 1, Hungary.
Estonian: Mylan Hungary Kft, H-2900 Komárom, Mylan utca 1, Ungari.
English: Hearing loss* or tinnitus*
Estonian: Kuulmise kadu* või tinnitus*
English: Medicinal products associated with bleeding risk
Estonian: Ravimid, millega seondub veritsusoht
English: Inhibition of prostaglandin synthesis may adversely affect the pregnancy and/or the embryo/foetal development.
Estonian: Prostaglandiinide sünteesi pärssimine võib kahjulikult mõjutada rasedust ja/või embrüo/loote arengut.
English: Patients should be followed carefully for any signs of bleeding including occult bleeding, especially during the first weeks of treatment and/or after invasive cardiac procedures or surgery.
Estonian: Kõiki veritsusele viitavaid sümptomeid patsientidel tuleb väga hoolikalt jälgida, kaasa arvatud varjatud veritsused, eriti esimeste ravinädalate jooksul ja/või pärast invasiivset kardiaalset protseduuri või kirurgiat.
English: Other concomitant therapy with clopidogrel
Estonian: Muu samaaegne ravi klopidogreeliga
English: Mylan Hungary Kft, Mylan utca 1, Komárom, H-2900, Hungary.
Estonian: Mylan Hungary Kft, Mylan utca 1, Komárom, H-2900, Ungari.
English: Patients should be told about the signs and symptoms of GI undesirable effects and what steps to take if they occur.
Estonian: Patsiente tuleb teavitada seedetrakti kõrvaltoimete ilmingutest ja sümptomitest ning sellest, mida teha, kui need tekivad.
English: Repeat-dose toxicity studies have shown that levels up to 200 mg/kg/day are well tolerated in rats; dogs appear to be more sensitive, probably due to the high sensitivity of canines to the ulcerogenic effects of NSAIDs.
Estonian: Korduvmanustamise toksilisusuuringud näitasid, et rotid taluvad hästi annuseid kuni 200 mg/kg/ööpäevas; koerad on tundlikumad, mis on tõenäoliselt tingitud koerlaste kõrgest tundlikkusest MSPVA ultserogeense toime suhtes.
English: ASA is poorly bound to plasma proteins and its apparent volume of distribution is low (10 l).
Estonian: ASH seondub vereplasma valkudega halvasti ja selle jaotusruumala on väike (10 l).
English: At low concentrations (<100 micrograms/ml), approximately 90% of salicylic acid is bound to albumin.
Estonian: Madalas kontsentratsioonis (<100 mikrogrammi/ml) on ligikaudu 90% salitsüülhappest seotud albumiiniga.
English: The incidence of severe cases was similar for clopidogrel and ASA.
Estonian: Tõsiste juhtude esinemissagedus oli klopidogreeli ja ASH korral sarnane.
English: Clopidogrel and the main circulating (inactive) metabolite bind reversibly in vitro to human plasma proteins (98% and 94% respectively).
Estonian: Klopidogreel ja peamine tsirkuleeriv (inaktiivne) metaboliit seonduvad in vitro pöörduvalt inimese vereplasma valkudega (vastavalt 98% ja 94%).
English: Their frequency is defined using the following conventions: common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Estonian: Nende esinemissagedus on defineeritud järgmiselt: sage (>1/100 kuni <1/10); aeg-ajalt (>1/1000 kuni <1/100); harv (>1/10 000 kuni <1/1000); väga harv (<1/10 000); teadmata (ei saa hinnata olemasolevate andmete alusel).
English: By preventing this clumping in some types of blood vessels (called arteries), antiplatelet medicinal products reduce the chances of blood clots forming (a process called atherothrombosis).
Estonian: Vältides sellist kokkukleepumist teatud veresoontes (nimetatakse arteriteks), vähendavad antiagregandid verehüüvete moodustumise võimalust (seda protsessi nimetatakse aterotromboosiks).
English: Bleeding is the most common reaction reported both in clinical studies as well as in the post-marketing experience where it was mostly reported during the first month of treatment.
Estonian: Veritsus on kõige sagedasem kõrvaltoime nii kliinilistes uuringutes kui ka turustusjärge kogemuse põhjal, mil sellest on teatatud enamasti esimesel ravikuul.
English: You should not breast-feed while using this medicine.
Estonian: Selle ravimi kasutamise ajal ei tohi te imetada.
English: Although no formal carcinogenicity studies have been performed with ASA, it has been shown that it is not a tumour promoter.
Estonian: Ehkki ASH kartsinogeensust ei ole formaalselt uuritud, on näidatud, et see ei soodusta kasvajaid.
English: • In patients with a history of asthma or allergic disorders since they are at increased risk of hypersensitivity reactions.
Estonian: • Varasema astma või allergilise häirega patsiendid, sest neil on suurem risk ülitundlikkusreaktsioonide tekkeks;
English: This is linked to the way your medicine works as it prevents the ability of blood clots to form.
Estonian: See on seotud ravimi toimega, sest see ennetab veretrombide teket.
English: The clinical relevance is unknown.
Estonian: Selle kliiniline tähtsus ei ole teada.
English: Risk management plan (RMP)
Estonian: • Riskijuhtimiskava
English: • fever, signs of infection or extreme tiredness.
Estonian: • palavik, infektsioonhaiguse nähud või väljendunud väsimus.
English: However, the limitations of these data and the uncertainties regarding extrapolation of ex vivo data to the clinical situation imply that no firm conclusions can be made for regular ibuprofen use, and no clinically relevant effect is considered to be likely for occasional ibuprofen use (see section 5.1).
Estonian: Nende andmete piiratus ja ebaselgus ex vivo andmete kohaldatavuse kohta kliinilisele olukorrale tähendab siiski, et kindlaid järeldusi ibuprofeeni regulaarse kasutamise kohta ei saa teha ning ibuprofeeni juhusliku kasutuse mõju on tõenäoliselt kliiniliselt mitteoluline (vt lõik 5.1).
English: Clinical studies indicate that doses up to 100 mg/day for restricted obstetrical use, which require specialised monitoring, appear safe.
Estonian: Kliinilised uuringud viitavad, et sünnitusabis piiratult kasutatavad annused kuni 100 mg/ööpäevas, mis nõuavad erijälgimist, on ohutud.
English: If a toxic dose has been ingested then admission to hospital is necessary.
Estonian: Toksilise annuse sissevõtmisel on vajalik hospitaliseerimine.
English: Clopidogrel has been evaluated for safety in more than 42,000 patients who have participated in clinical studies, including over 30,000 patients treated with clopidogrel plus ASA, and over 9,000 patients treated for 1 year or more.
Estonian: Klopidogreeli ohutust on uuritud enam kui 42000 patsiendil, kes osalesid kliinilistes uuringutes, sealhulgas klopidogreeli ja ASH-ga ravitud 30000 patsienti ning üle 9000 patsiendi, keda raviti 1 aasta või kauem.
English: From literature, limited data in Asian populations are available to assess the clinical implication of genotyping of this CYP on clinical outcome events.
Estonian: Kirjanduses on saadaval piiratud andmed asiaatide populatsiooni kohta, et hinnata CYP genotüpiseerimise mõju kliinilistele tulemustele.
English: • if you have a condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency because of the risk of a particular form of anaemia (low number of red blood cells).
Estonian: • kui teil on seisund, mida nimetatakse glükoos-6-fosfaatdehüdrogenaasi puudulikkuseks, sest sellega kaasneb teatud liiki aneemia (punaste vererakkude arvu langus) oht.
English: Treat other signs of intoxication symptomatically.
Estonian: Teisi intoksikatsiooninähte ravitakse sümptomaatiliselt.
English: This benefit was mostly driven by the statistically significant reduction in the incidence of MI [287 (4.6%) in the clopidogrel plus ASA group and 363 (5.8%) in the ASA group].
Estonian: See kasu seisnes peamiselt MI esinemissageduse statistiliselt olulises vähenemises (287 (4,6%) klopidogreel + ASH rühmas ja 363 (5,8%) ASH rühmas).
English: Hypoglycaemia*, gout* (see section 4.4)
Estonian: Hüpoglükeemia*, podagra* (vt lõik 4.4)
English: Proton Pump Inhibitors (PPI)
Estonian: Prootonpumba inhibiitorid (PPI)
English: Reye's syndrome is a very rare disease which can be fatal.
Estonian: Reye' sündroom on väga harva esinev haigus ning võib lõppeda surmaga.
English: Fever, oedema*
Estonian: Palavik, turse*
English: Patients should inform physicians and dentists that they are taking Clopidogrel/Acetylsalicylic acid Mylan before any surgery is scheduled and before any new medicinal product is taken.
Estonian: Patsiendid peavad teavitama arsti ja hambaarsti sellest, et nad võtavad Clopidogrel/Acetylsalicylic acid Mylani, enne mis tahes planeeritud kirurgilist vahelesegamist ning enne mis tahes uue ravimi võtmist.
English: However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 4 ‘Possible side effects').
Estonian: Kui te siiski olete mures veritsemise pärast, võtke kohe ühendust oma arstiga (vt lõik 4 „Võimalikud kõrvaltoimed“).
English: Glycoprotein IIb/IIIa inhibitors
Estonian: Glükoproteiin IIb/IIIa inhibiitorid
English: Renal excretion of unchanged active substance depends upon urinary pH. As urinary pH rises above 6.5, the renal clearance of free salicylate increases from <5% to >80%.
Estonian: Muutumatu toimeaine eritumine neerude kaudu sõltub uriini pH-st. Uriini pH tõustes üle 6,5 suureneb vaba salitsülaadi eritumine neerude kaudu tasemelt <5% tasemele >80%.
English: Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system listed in Appendix V
Estonian: Tervishoiutöötajatel palutakse kõigist võimalikest kõrvaltoimetest teatada riikliku teavitamissüsteemi (vt V lisa) kaudu.
English: Biotransformation and Elimination
Estonian: Biotransformatsioon ja eritumine
English: Thrombotic Thrombocytopenic Purpura (TTP) has been reported very rarely following the use of clopidogrel, sometimes after a short exposure.
Estonian: Väga harva on teatatud trombootilise trombotsütopeenilise purpuri (TTP) tekkest pärast klopidogreeli manustamist, mõnikord pärast lühiajalist kasutamist.
English: A patient with poor metaboliser status will possess two loss-of function alleles as defined above.
Estonian: Puuduliku metabolismiga patsiendil on kaks eelnevalt määratletud mittefunktsioneerivat alleeli.
English: Other medicines and Clopidogrel/Acetylsalicylic acid Mylan Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Estonian: Muud ravimid ja Clopidogrel/Acetylsalicylic acid Mylan Teatage oma arstile või apteekrile, kui te võtate või olete hiljuti võtnud või kavatsete võtta mis tahes muid ravimeid.
English: Therefore, this combination should be used with caution in patients taking low dose ASA for cardioprotection.
Estonian: Seetõttu tuleb seda kombinatsiooni kasutada ettevaatusega patsientidel, kes võtavad väikeses annuses ASH-d südame kaitseks.
English: The population included 27.8% women, 58.4% patients ≥60 years (26% ≥70 years) and 54.5% patients who received fibrinolytics.
Estonian: Populatsioonis oli naisi 27,8%, ≥60-aastaseid 58,4% (≥70-aastaseid 26%) ja fibrinolüütikume manustati 54,5% patsientidest.