FrancophonIA/ELRC3.0 huggingface dataset:
English: Note before adding Isentress:
Slovenian: Opozorilo, preden dodate zdravilo Isentress:
English: • This booklet tells you how to: º Mix Isentress into a liquid form º Measure the right dose using a syringe º GiveIsentresstoyourchild º Clean up
Slovenian: • Ta knjižica pojasnjuje, kako: º zmešate zdravilo Isentress v tekočo obliko º z uporabo brizge odmerite pravi odmerek º zdravilo Isentress daste otroku º opravite čiščenje
English: Do not open the Isentress sachets until you are ready to prepare a dose.
Slovenian: Ne odpirajte vrečic zdravila Isentress, dokler niste pripravljeni za pripravo odmerka.
English: • atazanavir (an antiretroviral medication)
Slovenian: • atazanavir (protiretrovirusno zdravilo)
English: Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.emea.europa.eu.
Slovenian: Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila http://www.ema.europa.eu.
English: • rifampicin (a medicine used to treat some infections such as tuberculosis)
Slovenian: • rifampicin (zdravilo za zdravljenje nekaterih okužb, kot je tuberkuloza)
English: *Number of patients with intensive pharmacokinetic (PK) results at the final recommended dose.
Slovenian: *Število bolnikov z intenzivnimi farmakokinetičnimi (FK) rezultati ob končnem priporočenem odmerku.
English: Factors that reduced the likelihood of developing resistance included lower baseline viral load and use of other active anti-retroviral agents.
Slovenian: Dejavniki, ki zmanjšajo verjetnost pojava odpornosti, vključujejo manjše izhodiščno virusno breme in uporabo drugih aktivnih protiretrovirusnih zdravil.
English: If you do take too many tablets, contact your doctor.
Slovenian: Če ste vzeli preveč tablet, se posvetujte z zdravnikom.
English: HIV genomes that fail to integrate cannot direct the production of new infectious viral particles, so inhibiting integration prevents propagation of the viral infection.
Slovenian: Genomi virusa HIV, ki se ne morejo integrirati, ne morejo neposredno proizvajati novih kužnih virusnih delcev in tako se z zavrtjem integracije prepreči nadaljnje širjenje virusne okužbe.
English: • feeling anxious; feeling of confusion; depressed mood; mood changes; panic attack
Slovenian: • občutek tesnobnosti, občutek zmedenosti, depresivno razpoloženje, spremembe razpoloženja, panični napad
English: You must give to your child within 30 minutes of mixing.
Slovenian: Mešanico morate otroku dati v 30 minutah po mešanju.
English: If it is less than 10 mL, put the tip back into the water and pull back on the plunger until you get to the 10 mL mark.
Slovenian: Če je vode manj kot 10 ml, konico brizge potopite nazaj v vodo in potegnite bat, dokler ne pridete do oznake 10 ml.
English: Renal clearance of unchanged medicinal product is a minor pathway of elimination.
Slovenian: Ledvični očistek nespremenjene učinkovine je manj pomembna pot izločanja.
English: 28 to less than 40
Slovenian: 28 do manj kot 40
English: ISENTRESS 600 mg tablet formulation has not been studied in paediatric patients (see section 4.2).
Slovenian: ISENTRESS 600 mg tablet niso preučevali pri pediatričnih bolnikih (glejte poglavje 4.2).
English: The effect of food on the granules for oral suspension formulation was not studied.
Slovenian: Vpliva hrane na zrnca za peroralno suspenzijo niso raziskovali.
English: Dizziness may influence some patients' ability to drive and use machines (see section 4.8).
Slovenian: Omotica lahko vpliva na sposobnost vožnje in upravljanja strojev (glejte poglavje 4.8).
English: Re-check the amount of Isentress in the syringe.
Slovenian: Ponovno preverite količino zdravila Isentress v brizgi.
English: Available pharmacodynamics/toxicological data in animals have shown excretion of raltegravir/metabolites in milk (for details see section 5.3).
Slovenian: Razpoložljivi farmakodinamični/toksikološki podatki pri živalih kažejo na izločanje raltegravirja/presnovkov v mleko (za podrobnosti glejte poglavje 5.3).
English: What Isentress is and what it is used for
Slovenian: Kaj je zdravilo Isentress in za kaj ga uporabljamo
English: This study enrolled 126 treatment experienced children and adolescents 2 to 18 years of age.
Slovenian: Ta študija je vključevala 126 že zdravljenih otrok in mladostnikov, starih od 2 do 18 let.
English: The 100 mg chewable tablet can be split into equal halves if necessary; however, breaking the tablets should be avoided.
Slovenian: 100 mg žvečljivo tableto se lahko deli na enaki polovici, če je to potrebno, vendar pa se je lomljenju tablet treba izogibati.
English: Raltegravir may be administered with or without food.
Slovenian: Raltegravir se lahko jemlje skupaj s hrano ali brez.
English: Patients received either the 400 mg tablet formulation (6 to 18 years of age) or the chewable tablet formulation (2 to less than 12 years of age).
Slovenian: Bolniki so prejeli zdravilo v obliki 400 mg tablet (od 6 do 18 let) ali v obliki žvečljivih tablet (od 2 do manj kot 12 let).
English: Pharmacotherapeutic group: antivirals for systemic use, other antivirals, ATC code: J05AX08.
Slovenian: Farmakoterapevtska skupina: zdravila za sistemsko zdravljenje virusnih infekcij, druga zdravila za sistemsko zdravljenje virusnih infekcij, oznaka ATC: J05AX08
English: Adults and paediatric population
Slovenian: Odrasli in pediatrična populacija
English: 1.5 mg/kg once daily 25 38.2 (38.4%)
Slovenian: 1,5 mg/kg enkrat na dan 25 38,2 (38,4 %)
English: 400 mg twice daily 18 14.1 (121 %)
Slovenian: 400 mg dvakrat na dan 18 14,1 (121 %)
English: Patients can remain on the granules for oral suspension as long as their weight is below 20 kg.
Slovenian: Bolniki se lahko zdravijo z zrnci za peroralno suspenzijo, vse dokler je njihova telesna masa manjša od 20 kg.
English: • Before you give Isentress to your child, check the expiration date.
Slovenian: • Predenotrokudastezdravilo Isentress, preverite datum izteka roka uporabnosti.
English: Severe, potentially life-threatening, and fatal skin reactions have been reported in patients taking raltegravir, in most cases concomitantly with other medicinal products associated with these reactions.
Slovenian: Poročali so o hudih, potencialno življenjsko nevarnih kožnih reakcijah in kožnih reakcijah s smrtnim izidom pri bolnikih, ki so jemali raltegravir, v večini primerov skupaj z drugimi zdravili, povezanimi s takšnimi reakcijami.
English: Gently swirl the mixing cup for 45 seconds in a circular motion to mix the granules and water.
Slovenian: Posodico za mešanje previdno vrtite 45 sekund s krožnim gibanjem, da boste zmešali zrnca in vodo.
English: Two tablets once a day
Slovenian: peroralna uporaba dve tableti enkrat na dan
English: Non-clinical toxicology studies, including conventional studies of safety pharmacology, repeated-dose toxicity, genotoxicity, developmental toxicity and juvenile toxicity, have been conducted with raltegravir in mice, rats, dogs and rabbits.
Slovenian: Predklinične toksikološke študije, vključno z običajnimi študijami farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih, genotoksičnosti, škodljivega vpliva na razvoj in juvenilnimi študijami so bile z raltegravirjem izvedene na miših, podganah, psih in kuncih.
English: The mixture should look cloudy.
Slovenian: Mešanica mora biti motnega videza.
English: Studies using isoform-selective chemical inhibitors and cDNA-expressed UDP-glucuronosyltransferases (UGT) show that UGT1A1 is the main enzyme responsible for the formation of raltegravir-glucuronide.
Slovenian: Študije z uporabo za izooblike selektivnih kemičnih zaviralcev in s cDNA- izraženih UDP-glukuronoziltransferaz (UGT) kažejo, da je UGT1A1 glavni encim, odgovoren za tvorbo raltegravirjevega glukuronida.
English: Recommended Dose for ISENTRESS For Oral Suspension in Full-Term Neonates (Birth to 4 weeks [28 days] of age*
Slovenian: Priporočeni odmerek zdravila ISENTRESS za peroralno suspenzijo pri donošenih novorojenčkih do starosti 4 tedne [28 dni]*
English: 60 film-coated tablets Multipack: 180 (3 bottles of 60) film-coated tablets
Slovenian: 60 filmsko obloženih tablet Multi pakiranje: 180 (3 plastenke po 60) filmsko obloženih tablet
English: Overall, considerable variability was observed in the pharmacokinetics of raltegravir.
Slovenian: Na splošno je bila opažena znatna variabilnost farmakokinetičnih lastnosti raltegravirja.
English: IMPAACT P1066 is a Phase I/II open label multicenter trial to evaluate the pharmacokinetic profile, safety, tolerability, and efficacy of raltegravir in HIV infected children.
Slovenian: Študija IMPAACT P1066 je odprto multicentrično preskušanje faze I/II za ovrednotenje farmakokinetičnega profila, varnosti, tolerabilnosti in učinkovitosti raltegravirja pri otrocih, okuženih z virusom HIV.
English: Put the tip of the syringe into the glass of water.
Slovenian: Konico brizge potopite v kozarec vode.
English: The rashes observed in clinical studies were mild to moderate in severity and did not result in discontinuation of therapy (see section 4.4).
Slovenian: Izpuščaji, ki so jih opazili v kliničnih študijah, so bili po jakosti blagi do zmerni in niso vodili v prenehanje zdravljenja (glejte poglavje 4.4).
English: Sources of variability may include differences in co-administration with food and concomitant medicines.
Slovenian: Razlogi za variabilnost so med drugim lahko tudi razlike pri sočasnem jemanju s hrano in sočasnem zdravljenju z drugimi zdravili.
English: 11 to less than 25 kg Chewable tablet
Slovenian: 11 do manj kot 25 kg žvečljiva tableta
English: • trouble sleeping; abnormal dreams; nightmare; abnormal behaviour; feelings of deep sadness and unworthiness
Slovenian: • težave s spanjem, nenormalne sanje, nočne more, nenormalno obnašanje, občutki globoke žalosti in ničvrednosti
English: Cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to combination antiretroviral therapy (CART).
Slovenian: Poročali so o primerih osteonekroze, predvsem pri bolnikih, ki so imeli splošno znane dejavnike tveganja, napredovalo bolezen HIV ali pa so se dolgotrajno zdravili s kombiniranim protiretrovirusnim zdravljenjem (CART).
English: A further 531 treatment-naïve adults have received raltegravir 1,200 mg once daily with emtricitabine and tenofovir disoproxil fumarate for up to 96 weeks.
Slovenian: Nadaljnjih 531 predhodno nezdravljenih odraslih je prejemalo raltegravir 1.200 mg enkrat na dan z emtricitabinom in tenofovirdizoproksil fumaratom do 96 tednov.
English: Push the plunger of the blue syringe into the syringe as far as it goes.
Slovenian: Bat modre brizge potisnite v brizgo, kolikor daleč gre.
English: There are no data for the use of raltegravir 1,200 mg once daily in pregnant women.
Slovenian: Ni podatkov o uporabi raltegravirja 1.200 mg enkrat na dan pri nosečnicah.
English: Birth - 48 hours
Slovenian: od rojstva do 48 ur
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Slovenian: Znaki osteonekroze so okorelost, bolečnost in bolečine v sklepih (predvsem v kolčnem, kolenskem in ramenskem sklepu) ter težave pri gibanju.
English: With twice-daily dosing, pharmacokinetic steady state is achieved rapidly, within approximately the first 2 days of dosing.
Slovenian: Pri odmerjanju dvakrat na dan je stanje dinamičnega ravnovesja hitro doseženo, približno v prvih 2 dneh po začetku zdravljenja.
English: If you forget to take Isentress
Slovenian: Če ste pozabili vzeti zdravilo Isentress
English: Fill the clean glass with room-temperature drinking water from your tap or using bottled still water.
Slovenian: Čist kozarec napolnite s pitno vodo sobne temperature iz pipe ali uporabite ustekleničeno vodo brez mehurčkov.
English: As a general rule, when deciding to use antiretroviral agents for the treatment of HIV infection in pregnant women and consequently for reducing the risk of HIV vertical transmission to the newborn, the animal data as well as the clinical experience in pregnant women should be taken into account in order to characterise the safety for the foetus.
Slovenian: Pri odločanju o uporabi protiretrovirusnih zdravil za zdravljenje okužbe z virusom HIV pri nosečnicah in s tem o zmanjševanju tveganja za prenos virusa HIV na novorojenca je za opredelitev varnosti za plod praviloma treba upoštevati podatke iz študij na živalih kot tudi klinične izkušnje pri nosečnicah.
English: N=26
Slovenian: parameter n = 26
English: Then find the mL mark on the syringe barrel that matches your child's dose.
Slovenian: Potem na telesu brizge poiščite oznako ml, ki se ujema z otrokovim odmerkom.
English: Inhibition of integrase prevents the covalent insertion, or integration, of the HIV genome into the host cell genome.
Slovenian: Zavrtje integraze prepreči kovalentno insercijo ali integracijo genoma virusa HIV v celični genom gostitelja.
English: Dosing is weight based from birth as specified in Table 1 and Table 2.
Slovenian: Odmerjanje temelji na telesni masi od rojstva, kot je prikazano v preglednici 1 in preglednici 2.
English: It is unknown whether raltegravir/metabolites are excreted in human milk.
Slovenian: Ni znano, ali se raltegravir/presnovki izločajo v materino mleko.
English: Check your prescription
Slovenian: 8. korak Preverite svoj recept
English: In a single-cycle infection assay, raltegravir inhibited infection of 23 HIV isolates representing 5 non-B subtypes and 5 circulating recombinant forms with IC50 values ranging from 5 to 12 nM.
Slovenian: V enem infekcijskem ciklu je raltegravir inhibiral okužbo 23 HIV izolatov, ki so predstavljali 5 podtipov, razen podtipa B, in 5 cirkulirajočih rekombinantnih oblik z vrednostmi IC50 od 5 do 12 nM.
English: Rifampicin reduces plasma levels of raltegravir; the impact on the efficacy of raltegravir is unknown.
Slovenian: Rifampicin zmanjša plazemske vrednosti raltegravirja, vpliv na učinkovitost raltegravirja pa ni znan.
English: • It is very important that you measure the water and Isentress carefully using the correct syringe.
Slovenian: • Zelopomembno je, da vodo in zdravilo Isentress skrbno odmerite s pravo brizgo.
English: Response
Slovenian: odziv
English: Viruses harbouring a mutation at amino acid 148, along with one or more other raltegravir resistance mutations, may also have clinically significant resistance to dolutegravir.
Slovenian: Virusi z mutacijo aminokisline 148 skupaj z eno ali več drugimi mutacijami, povezanimi z odpornostjo proti raltegravirju, so lahko klinično pomembno odporni tudi proti dolutegravirju.
English: Safety profiles in the subgroup of patients in Phase III trials taking proton pump inhibitors or H2 antagonists were comparable with those who were not taking these antacids.
Slovenian: Varnostni profili pri podskupini bolnikov v kliničnih preskušanjih faze III, ki so prejemali zaviralce protonske črpalke ali antagoniste histaminskih receptorjev H2, so bili primerljivi s tistimi pri bolnikih, ki teh zdravil niso prejemali.
English: Your doctor can tell you if it is safe to take Isentress with other medicines.
Slovenian: Zdravnik vam lahko pove, ali je zdravilo Isentress varno jemati skupaj z drugimi zdravili.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV disease and/or long-term exposure to combination anti-retroviral therapy.
Slovenian: Čeprav so vzroki za osteonekrozo različni (vključno z uporabo kortikosteroidov, uživanjem alkohola, hudo imunosupresijo in višjim indeksom telesne mase), so o primerih osteonekroze poročali še posebej pri bolnikih z napredovalo okužbo z boleznijo HIV in/ali pri dolgotrajnem kombiniranem protiretrovirusnem zdravljenju.
English: • Isentress 1,200 mg (two 600 mg tablets once daily) is not recommended in pregnancy because it has not been studied in pregnant women.
Slovenian: • Uporaba zdravila Isentress 1.200 mg (dve 600 mg tableti enkrat na dan) med nosečnostjo ni priporočljiva, saj uporabe tega zdravila pri nosečnicah niso raziskovali.
English: Tap it with your finger to move any air bubbles up.
Slovenian: Potrkajte po njej s prstom, da se bodo morebitni zračni mehurčki dvignili na vrh.
English: Based on a formulation comparison study in healthy adult volunteers, the chewable tablet and granules for oral suspension have higher oral bioavailability compared to the 400 mg tablet.
Slovenian: Na podlagi primerjalne študije farmacevtskih oblik pri zdravih odraslih prostovoljcih imajo žvečljive tablete in zrnca za peroralno suspenzijo višjo peroralno biološko razpoložljivost kot 400 mg tablete.
English: For weight between 11 and 20 kg either formulation can be used.
Slovenian: Za telesno maso med 11 in 20 kg se lahko uporabi eno ali drugo obliko.
English: Isentress might interact with other medicines.
Slovenian: Zdravilo Isentress lahko medsebojno deluje z drugimi zdravili.
English: Raltegravir achieved virologic responses (using Not Completer=Failure approach) of HIV RNA < 50 copies/mL in 61.7 % of patients at Week 16, in 62.1 % at Week 48 and in 57.0 % at Week 96.
Slovenian: Raltegravir je dosegel virološke odzive (z uporabo metode nedokončanje = neuspeh) HIV RNA < 50 kopij/ml pri 61,7 % bolnikov po 16 tednih, pri 62,1 % po 48 tednih in pri 57,0 % po 96 tednih.
English: Do not change the dose or stop taking this medicine without first talking with your doctor, pharmacist or nurse.
Slovenian: Ne spreminjajte odmerka in ne prenehajte jemati tega zdravila, ne da bi se o tem prej posvetovali z zdravnikom, farmacevtom ali medicinsko sestro.
English: The dose should be administered orally within 30 minutes of mixing.
Slovenian: Odmerek je treba dati peroralno v 30 minutah po mešanju.
English: The most frequently reported adverse reactions during treatment were headache, nausea and abdominal pain.
Slovenian: Neželeni učinki med zdravljenjem, o katerih so najpogosteje poročali, so bili glavobol, navzea in bolečine v trebuhu.
English: • However, if it is time for your next dose, skip the missed dose and go back to your regular schedule.
Slovenian: • Če je že skoraj čas, da vzamete naslednji odmerek, pozabljeni odmerek izpustite in nadaljujte z jemanjem zdravila ob običajnem času.
English: • tipranavir/ritonavir (antiretroviral medicines)
Slovenian: • tipranavir/ritonavir (protiretrovirusni zdravili)
English: Raltegravir and efavirenz were administered with emtricitabine (+) tenofovir disoproxil fumarate.
Slovenian: Raltegravir in efavirenz so dajali z emtricitabinom (+) tenofovirdizoproksil fumaratom.
English: No specific information is available on the treatment of overdose with raltegravir.
Slovenian: Posebne informacije o zdravljenju v primeru prevelikega odmerjanja raltegravirja niso na voljo.
English: BENCHMRK 1 and 2 Pooled
Slovenian: združeni podatki študij BENCHMRK 1 in 2 parameter
English: For observed C12 hr in BENCHMRK 1 and 2 the coefficient of variation (CV) for inter-subject variability = 212 % and the CV for intra-subject variability = 122 %.
Slovenian: V študijah BENCHMRK 1 in 2 je bil koeficient variacije (CV) variabilnosti vrednosti C12 ur med osebami = 212 %, pri posamezni osebi pa = 122 %.
English: In a comparison of 30 subjects with *28/*28 genotype to 27 subjects with wild-type genotype, the geometric mean ratio (90 % CI) of AUC was 1.41 (0.96, 2.09) and the geometric mean ratio of C12 hr was 1.91 (1.43, 2.55).
Slovenian: Primerjava med 30 osebami z genotipom *28/*28 in 27 osebami z divjim genotipom je pokazala, da je bilo geometrijsko srednje razmerje (90-odstotni IZ) vrednosti AUC 1,41 (0,96; 2.09), geometrijsko srednje razmerje vrednosti C12 ur pa 1,91 (1,43; 2,55).
English: (increased solubility)
Slovenian: (povečana topnost)
English: There were no clinically important pharmacokinetic differences due to gender, race or body mass index (BMI) in adults.
Slovenian: Klinično pomembnih razlik v farmakokinetiki zaradi spola, rase ali indeksa telesne mase (ITM) pri odraslih ni bilo.
English: Isentress chewable tablets contain aspartame Isentress contains aspartame, a source of phenylalanine, which may be harmful to people with phenylketonuria.
Slovenian: Isentress žvečljive tablete vsebujejo aspartam Zdravilo Isentress vsebuje aspartam, vir fenilalanina, ki lahko škoduje ljudem s fenilketonurijo.
English: Switch to raltegravir
Slovenian: Prehod na raltegravir
English: Slowly push the plunger to make the air come out.
Slovenian: Bat počasi potiskajte, da bo zrak šel ven.
English: In the second study (n=16), the median cerebrospinal fluid concentration was 3 % (range 1 to 61 %) of the corresponding plasma concentration.
Slovenian: V drugi študiji (n = 16) je mediana koncentracija v cerebrospinalni tekočini znašala 3 % (v intervalu od 1 do 61 %) odgovarjajoče koncentracije v plazmi.
English: In these 26 infants and toddlers, the frequency, type and severity of drug related adverse reactions through Week 48 were comparable to those observed in adults.
Slovenian: Pri teh 26 dojenčkih in malčkih so bile pogostnost, vrsta in resnost z zdravilom povezanih neželenih učinkov do 48. tedna primerljive s tistimi, ki so jih opazili pri odraslih.
English: Delay in stopping raltegravir treatment or other suspect agents after the onset of severe rash may result in a life-threatening reaction.
Slovenian: Odlašanje s prenehanjem uporabe raltegravirja ali drugih zadevnih zdravil po pojavu hudega izpuščaja lahko povzroči življenjsko nevarne reakcije.
English: • 6 syringes
Slovenian: • 6 brizg
English: If it is less than the prescribed dose, put the tip back into the cup of prepared Isentress and pull back on the plunger until you get to the right dose mark.
Slovenian: Če je količina manjša od predpisanega odmerka, znova potopite konico v posodico s pripravljenim zdravilom Isentress in potegnite bat ven, dokler ne dosežete oznake pravega odmerka.
English: If you stop taking Isentress It is important that you take Isentress exactly as your doctor has instructed.
Slovenian: Če ste prenehali jemati zdravilo Isentress Pomembno je, da zdravilo Isentress jemljete natančno po navodilih zdravnika.
English: Mutations at amino acid 143 confer greater resistance to raltegravir than to elvitegravir, and the E92Q mutation confers greater resistance to elvitegravir than to raltegravir.
Slovenian: Mutacije aminokisline 143 so povezane z večjo odpornostjo proti raltegravirju kot elvitegravirju, mutacija E92Q pa je povezana z večjo odpornostjo proti elvitegravirju kot raltegravirju.
English: In some patients with advanced HIV infection and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Slovenian: Pri nekaterih bolnikih z napredovalo okužbo z virusom HIV in predhodno oportunistično okužbo, se lahko kmalu po začetku zdravljenja okužbe z virusom HIV pojavijo znaki in simptomi vnetja zaradi predhodne okužbe.
English: Administration of the chewable tablet with a high fat meal does not affect raltegravir pharmacokinetics to a clinically meaningful degree and the chewable tablet can be administered without regard to food.
Slovenian: Jemanje žvečljivih tablet z obrokom z veliko maščobami ne vpliva na farmakokinetiko raltegravirja do klinično pomembne stopnje, zato se lahko žvečljive tablete jemlje ne glede na hrano.
English: • NEW Directions for dose preparation
Slovenian: • NOVO Navodila za pripravo odmerka
English: In two studies of HIV-1 infected patients who received raltegravir 400 mg twice daily, raltegravir was readily detected in the cerebrospinal fluid.
Slovenian: V dveh študijah pri bolnikih, okuženih z virusom HIV-1, ki so prejemali raltegravir 400 mg dvakrat na dan, so raltegravir hitro zaznali v cerebrospinalni tekočini.
English: • mental disorder
Slovenian: • duševne motnje
English: Age (hours/days) at PK Sampling
Slovenian: Starost (ure/dnevi) ob odvzemu vzorca za FK