FrancophonIA/ELRC3.0 huggingface dataset:
English: Co-administration of ciclosporin and aliskiren is not recommended (see section 4.3).
Slovenian: Sočasna uporaba ciklosporina in aliskirena ni priporočena (glejte poglavje 4.3).
English: There have been reports from clinical trials and from the post-marketing setting associated with the use of Sandimmun.
Slovenian: O tem so poročali iz kliničnih študij in na podlagi izkušenj z uporabo zdravila Sandimmun po prihodu zdravila na trg.
English: Sandimmun concentrate for solution for infusion contains approximately 34.4 v/v ethanol (alcohol).
Slovenian: Zdravilo Sandimmun koncentrat za raztopino za infundiranje vsebuje približno 34,4 % volumskega deleža etanola (alkohola).
English: METHOD AND ROUTE(S) OF ADMINISTRATION Oral use
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA peroralna uporaba
English: It is recommended that Sandimmun be administered on a consistent schedule with regard to time of day and in relation to meals.
Slovenian: Zdravilo Sandimmun je priporočljivo jemati vedno ob istem času, kar pomeni ob isti uri in z enakim razporedom glede na obroke.
English: If Sandimmun concentrate for solution for infusion is used, the recommended dose is approximately one-third of the corresponding Sandimmun oral dose, and it is recommend that patients be switched to oral therapy as soon as possible.
Slovenian: Pri uporabi zdravila Sandimmun koncentrat za raztopino za infundiranje je priporočeni odmerek približno ena tretjina odmerka ustrezne peroralne oblike zdravila Sandimmun.
English: • Excessive growth of body and facial hair.
Slovenian: • prekomerna poraščenost po obrazu in telesu
English: The white stopper and tube should remain in the bottle.
Slovenian: Bel čep s potopno cevko naj ostane v steklenici.
English: This dose should be maintained as the daily dose for 1 to 2 weeks post-operatively, being gradually reduced in accordance with blood levels according to local immunosuppressive protocols until a recommended maintenance dose of about 2 to 6 mg/kg given in 2 divided doses is reached.
Slovenian: S tem dnevnim odmerkom je treba nadaljevati 1 do 2 tedna po operaciji, nato pa ga je treba postopno zniževati v skladu s koncentracijo zdravila v krvi po lokalnem imunosupresivnem protokolu do priporočenega vzdrževalnega odmerka približno 2 do
English: Co-administration of bosentan and ciclosporin in healthy volunteers increases the bosentan exposure several-fold and there was a 35% decrease in ciclosporin exposure.
Slovenian: Pri zdravih prostovoljcih je pri sočasni uporabi bosentana in ciklosporina prišlo do nekajkratnega povečanja izpostavljenosti bosentanu in do zmanjšanja izpostavljenosti ciklosporinu za 35 %.
English: Preference should be given to an antihypertensive agent that does not interfere with the pharmacokinetics of ciclosporin, e.g. isradipine (see section 4.5).
Slovenian: Izbrati je treba ustrezno antihipertenzivno zdravilo, ki ne vpliva na farmakokinetiko ciklosporina, na primer izradipin (glejte poglavje 4.5).
English: Flakes or small bits (sediments) in the medicine do not affect how the medicine works or how safe it is to use.
Slovenian: Kosmiči ali manjša usedlina v zdravilu ne vplivajo na delovanje zdravila in na njegovo varnost, pa tudi priprave pravilnega odmerka z brizgo ne motijo.
English: What Sandimmun is and what it is used for What you need to know before you take Sandimmun How to take Sandimmun
Slovenian: Kaj je zdravilo Sandimmun in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Sandimmun Kako jemati zdravilo Sandimmun
English: Renal function must be assessed frequently throughout therapy to allow dosage adjustment (see section 4.2).
Slovenian: Med zdravljenjem je potrebno za prilagajanje odmerka zdravila pogosto ocenjevati ledvično funkcijo (glejte poglavje 4.2).
English: Elevations in serum creatinine were observed in the studies using everolimus or sirolimus in combination with full-dose ciclosporin for microemulsion.
Slovenian: V študijah, v katerih so uporabljali everolimus ali sirolimus v kombinaciji s ciklosporinom v mikroemulziji v polnem odmerku, so opažali zvišanje koncentracije kreatinina v serumu.
English: For the full list of excipients see section 6.1.
Slovenian: Za celoten seznam pomožnih snovi glejte poglavje 6.1.
English: Precautions to be taken before handling or administering the medicinal product For instructions on dilution of the medicinal product before administration, see section 6.6.
Slovenian: Za navodila glede redčenja zdravila pred dajanjem, glejte poglavje 6.6.
English: • Pain in your muscles, muscle spasm.
Slovenian: • bolečine v mišicah, mišični krči
English: Use of Sandimmun in children for non-transplantation indications other than nephrotic syndrome cannot be recommended (see section 4.4).
Slovenian: Pri otrocih ni mogoče priporočati uporabe zdravila Sandimmun za indikacije, ki niso povezane s presaditvijo, razen za uporabo pri nefrotskem sindromu (glejte poglavje 4.4).
English: Additional precautions in non-transplantation indications Patients with impaired renal function (except nephrotic syndrome patients with a permissible degree of renal impairment), uncontrolled hypertension, uncontrolled infections, or any kind of malignancy should not receive ciclosporin.
Slovenian: Dodatna opozorila pri indikacijah, ki niso povezane s presaditvijo Ciklosporina ne smejo prejemati bolniki z okvaro ledvic (razen pri bolnikih, ki imajo nefrotski sindrom in še dopustno stopnjo ledvične okvare), bolniki z neurejeno hipertenzijo, z neozdravljeno okužbo ali s katerokoli maligno boleznijo.
English: Cases of acute nephrotoxicity reported disorders of ion homeostasis, such as hyperkalaemia, hypomagnesaemia, and hyperuricaemia.
Slovenian: Pri primerih akutnega toksičnega delovanja na ledvice so poročali o porušeni homeostazi ionov, kot so hiperkaliemija, hipomagneziemija in hiperurikemija.
English: Experience with Sandimmun in pregnancy is limited.
Slovenian: Izkušnje z zdravilom Sandimmun v nosečnosti so omejene.
English: Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or medication and increased susceptibility for infections.
Slovenian: Običajno je smiselno začeti z najnižjim odmerkom v okviru priporočenega odmerjanja, saj so pri starejših bolnikih pogosteje prisotni zmanjšana funkcija jeter, ledvic in srca, druge sočasne bolezni in zdravljenje ter povečana dovzetnost za okužbe.
English: • Stomach ulcer.
Slovenian: • želodčni ulkus (razjeda)
English: Sandimmun should be administered with caution in patients with neurological Behcet`s syndrome.
Slovenian: Pri odmerjanju zdravila Sandimmun bolnikom z nevrološkim Behcetovim sindromom je potrebna previdnost.
English: Usually, higher doses are used before and just after your transplant.
Slovenian: Pred presaditvijo in takoj po njej običajno uporabljamo višje odmerke.
English: Caution should be observed when co-administering ciclosporin with drugs that substantially increase or decrease ciclosporin plasma concentrations, through inhibition or induction of CYP3A4 and/or Pglycoprotein (see section 4.5).
Slovenian: Previdnost je potrebna pri sočasnem dajanju ciklosporina in zdravil ki bistveno zvišajo ali znižajo koncentracijo ciklosporina v plazmi, ker zavirajo ali inducirajo CYP3A4 in/ali P-glikoprotein (glejte poglavje 4.5).
English: If there is no alternative, it is recommended to closely monitor blood levels of ciclosporin, renal function, and for side effects of ciclosporin.
Slovenian: Če razen uporabe peroralnega eritromicina ni druge možnosti, je priporočeno natančno spremljanje koncentracije ciklosporina v krvi, delovanja ledvic in neželenih učinkov ciklosporina.
English: Frequent monitoring of renal function is therefore required according to local guidelines for the indication in question (see sections 4.2 and
Slovenian: Iz navedenih razlogov je treba pogosto spremljati ledvično funkcijo v skladu s smernicami za posamezno indikacijo (glejte poglavji 4.2 in 4.8)
English: If medicinal products known to increase ciclosporin levels are given concomitantly, frequent assessment of renal function and careful monitoring for ciclosporin-related side effects may be more appropriate than blood level measurement.
Slovenian: Ob sočasnem jemanju zdravil, za katere je znano, da zvišujejo koncentracijo ciklosporina, je morda namesto določanja koncentracije ciklosporina v krvi bolj primerno pogosto ocenjevanje ledvične funkcije in skrbno spremljanje bolnika glede morebitnih neželenih učinkov ciklosporina.
English: Additional precautions in atopic dermatitis
Slovenian: Dodatna opozorila pri atopijskem dermatitisu
English: • Symptoms of brain disorders including sudden fits, mental confusion, sleeplessness, disorientation, disturbance of vision, unconsciousness, sense of weakness in the limbs, impaired movements.
Slovenian: • simptomi možganskih okvar, ki lahko vključujejo nenadne epileptične napade, duševno zmedenost, nespečnost, dezorientiranost, motnje vida, nezavest, občutek šibkosti v okončinah,
English: • Destruction of red blood cells, involving kidney problems with symptoms such as swelling of the face, stomach, hands and/or feet, decreased urination, breathing difficulty, chest pain, fits,
Slovenian: • razpadanje eritrocitov, ki vključuje težave z ledvicami skupaj s simptomi, kot so otekanje v obraz, trebuh, roke in/ali stopala, zmanjšano izločanje vode z urinom, oteženo dihanje, bolečine v prsih, epileptični napadi, nezavest
English: • Liver problems and damage with or without yellow skin and eyes, nausea, loss of appetite and dark urine.
Slovenian: • težave z jetri in okvara jeter s prisotno ali odsotno rumeno obarvanostjo kože in oči, občutek slabosti, izguba apetita in temno obarvan urin;
English: Following oral administration of Sandimmun peak blood concentrations are reached within 1 to 6 hours.
Slovenian: Po peroralnem odmerjanju zdravila Sandimmun doseže ciklosporin najvišjo koncentracijo v krvi v 1-6 urah.
English: There is a high variability in the data reported on the terminal elimination half-life of ciclosporin, depending on the assay applied and the target population.
Slovenian: Podatki za končni razpolovni čas izločanja ciklosporina iz telesa znatno variirajo, odvisno od uporabljene metode določanja in od zajetih preiskovancev.
English: In patients with kidney problems, the first dose taken each day should not be more than 2.5 mg per kilogram body weight.
Slovenian: Pri bolnikih, ki imajo težave z ledvicami, naj prvi odmerek, ki ga vzamejo čez dan, ne presega 2,5 mg na kilogram telesne mase.
English: How much Sandimmun to take
Slovenian: Koliko zdravila Sandimmun jemati
English: - If you have any further questions, ask your doctor or pharmacist.
Slovenian: Če imate dodatna vprašanja, se posvetujte s svojim zdravnikom ali farmacevtom.
English: Push the medicine out of the syringe into a small glass (not plastic) containing liquids, preferably cold chocolate drink, milk, fruit juice or cola - Make sure that the syringe does not touch the liquid in the glass.
Slovenian: Iztisnite zdravilo iz brizge v majhen stekleni kozarec (ne plastičen) z nekaj tekočine, najbolje s hladnim čokoladnim napitkom, mlekom sadnim sokom ali kolo.
English: Statin therapy needs to be temporarily withheld or discontinued in patients with signs and symptoms of myopathy or those with risk factors predisposing to severe renal injury, including renal failure, secondary to rhabdomyolysis.
Slovenian: Zdravljenje s statini je treba začasno ali dokončno prekiniti pri bolnikih z znaki in simptomi miopatije in pri tistih z dejavniki tveganja, ki povečujejo dovzetnost za hudo ledvično okvaro, vključno z ledvično odpovedjo zaradi rabdomiolize.
English: Push the tube unit with the white stopper firmly into the neck of the bottle.
Slovenian: Čvrsto potisnite potopno cevko z belim čepom v vrat steklenice.
English: Infectious causes of uveitis should be ruled out before immunosuppressants can be used.
Slovenian: Pred uporabo imunosupresivnih zdravil je treba izključiti možnost infekcijskega vzroka uveitisa.
English: Sandimmun soft capsules contain 12.8% v/v ethanol (10.2% m/v).
Slovenian: Sandimmun mehke kapsule vsebujejo 12,8 % volumskega deleža etanola (kar je 10,2 % masnega deleža).
English: {Name and address} {tel} {fax}
Slovenian: {Ime in naslov} {tel.} {faks} {e-pošta}
English: Concomitant use of ciclosporin and tacrolimus should be avoided (see section 4.5).
Slovenian: Sočasni uporabi ciklosporina in takrolimusa se je treba izogibati (glejte poglavje 4.5).
English: Sandimmun 50 mg/ml concentrate for solution for infusion ciclosporin
Slovenian: Navodilo za uporabo Sandimmun 50 mg/ml koncentrat za raztopino za infundiranje ciklosporin
English: Subsequent relapse may be managed with a further course of Sandimmun.
Slovenian: Nadaljnji ponovni zagon bolezni je mogoče zdraviti s ponovnim ciklom zdravljenja z zdravilom Sandimmun.
English: - Close the bottle with the cap provided.
Slovenian: Zaprite steklenico s priloženo zaporko.
English: These conditions are often related to a high total immunosuppressive burden and should be considered in the differential diagnosis in immunosuppressed patients with deteriorating renal function or neurological symptoms.
Slovenian: Te bolezni so pogosto povezane z visoko skupno obremenitvijo z imunosupresivnim zdravljenjem in pri bolnikih z zmanjšano imunsko odzivnostjo in s poslabšanjem delovanja ledvic ali z nevrološkimi simptomi je treba pomisliti tudi na možnost navedenih bolezni.
English: Sandimmun oral solution is provided with two syringes for measuring the doses.
Slovenian: K peroralni raztopini Sandimmun sta priloženi dve brizgi za pripravljanje odmerkov.
English: Fertility There is limited data on the effect of Sandimmun on human fertility (see section 5.3).
Slovenian: Na voljo je le malo podatkov o vplivu zdravila Sandimmun na plodnost pri ljudeh (glejte poglavje
English: Infusion is continued at this dose level during the immediate post-transplant period of up to 2 weeks, before a change is made to oral maintenance therapy with Sandimmun at daily doses of about 12.5 mg/kg given in 2 divided doses.
Slovenian: do 5 mg/kg na dan. S takim odmerkom v intravenski infuziji je v obdobju takoj po presaditvi priporočeno nadaljevati do 2 tedna, nato pa preiti na peroralno vzdrževalno zdravljenje z zdravilom Sandimmun v dnevnem odmerku približno 12,5 mg/kg v dveh deljenih odmerkih.
English: Once an ampoule is opened, the contents should be used immediately.
Slovenian: Vsebino odprte ampule je treba uporabiti takoj.
English: • Brain problems with signs such as seizures, confusion, feeling disorientated, being less responsive, personality changes, feeling agitated, sleeplessness, changes to your sight, blindness, coma, paralysis of part or all of the body, stiff neck, loss of coordination with or without unusual speech or eye movements.
Slovenian: • možganske okvare z znaki, kot so epileptični napad, zmedenost, dezorientiranost, zmanjšana odzivnost, osebnostne spremembe, huda tesnoba z nemirom (agitacija), nespečnost, motnje vida, slepota, koma, ohromelost dela ali celega telesa, trd vrat, izguba koordinacije gibov s prisotnimi ali odsotnimi težavami z govorjenjem ali premikanjem oči;
English: It may be stored at room temperature not exceeding 30°C.
Slovenian: ki ne presega 30 °C.
English: How much Sandimmun you will be given
Slovenian: Koliko zdravil Sandimmun boste prejeli
English: In most cases, Sandimmun concentrate for solution for infusion is preferred for this purpose.
Slovenian: V večini primerov je za to najbolje uporabiti Sandimmun koncentrat za raztopino za infundiranje, pri čemer je priporočeni intravenski odmerek 3
English: • Swelling at the back of the eye which may be associated with an increase in pressure inside the head and eyesight disturbances.
Slovenian: • otekanje na zadnjem delu očesa, ki je lahko povezano s povečanjem tlaka v glavi in motnjami vida Če vas to huje prizadene, obvestite svojega zdravnika.
English: In non-transplant patients, occasional monitoring of ciclosporin blood levels is recommended, e.g. when Sandimmun is co-administered with substances that may interfere with the pharmacokinetics of ciclosporin, or in the event of unusual clinical response (e.g. lack of efficacy or increased drug intolerance such as renal dysfunction).
Slovenian: Pri bolnikih z indikacijami, ki niso povezane s presaditvijo, je priporočeno občasno spremljanje koncentracije ciklosporina v krvi, kadar na primer prejemajo zdravilo Sandimmun sočasno z učinkovinami, ki lahko vplivajo na farmakokinetiko ciklosporina, ali v primeru neobičajnega kliničnega odziva (na primer neučinkovitosti zdravila ali povečane intolerance za zdravilo, kot je ledvična disfunkcija).
English: Ciclosporin is extensively metabolised by the liver.
Slovenian: Ciklosporin se obsežno presnavlja v jetrih.
English: Ciclosporin undergoes minimal renal elimination and its pharmacokinetics are not extensively affected by renal impairment (see section 5.2).
Slovenian: Ciklosporin se izloča preko ledvic le v majhni meri, zato okvara ledvic ne vpliva na njegovo farmakokinetiko (glejte poglavje 5.2).
English: PHARMACEUTICAL FORM AND CONTENTS Concentrate for solution for infusion containing 50 mg ciclosporin per mL.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA Koncentrat za raztopino za infundiranje vsebuje 50 mg ciklosporina na ml.
English: However, serious symptoms of intoxication have been reported following accidental parenteral overdosage with ciclosporin in premature neonates.
Slovenian: Resne simptome zastrupitve pa so opisovali pri nedonošenčkih po nenamernem parenteralnem vnosu prevelikega odmerka ciklosporina.
English: METHOD AND ROUTE(S) OF ADMINISTRATION Intravenous administration
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA intravenska uporaba
English: Regular monitoring of blood pressure is required during Sandimmun therapy.
Slovenian: Med zdravljenjem z zdravilom Sandimmun je potrebno redno spremljanje krvnega tlaka.
English: Caution is required with concomitant use of potassium-sparing medicinal products (e.g. potassiumsparing diuretics, ACE inhibitors, angiotensin II receptor antagonists) or potassium-containing medicinal products since they may lead to significant increases in serum potassium (see section 4.4).
Slovenian: Previdnost je potrebna pri sočasni uporabi zdravil, ki varčujejo s kalijem (na primer diuretikov, ki varčujejo s kalijem, zaviralcev angiotenzinske konvertaze, zaviralcev receptorjev angiotenzina II) ali zdravil, ki vsebujejo kalij, ker lahko pride do pomembnega zvišanja koncentracije kalija v serumu (glejte poglavje 4.4).
English: In the 24-month rat study conducted at 0.5, 2, and 8 mg/kg/day, pancreatic islet cell adenomas significantly exceeded the control rate at the low dose level.
Slovenian: 0,5 mg, 2 mg in 8 mg/kg/dan, so bili adenomi pankreasnih otočkov pri uporabi nizkih odmerkov statistično značilno pogostejši kot v kontrolni skupini.
English: Patients on Sandimmun should not receive concomitant ultraviolet B irradiation or PUVA photochemotherapy.
Slovenian: Bolniki, ki jemljejo zdravilo Sandimmun, se ne smejo sočasno zdraviti z ultravijoličnimi žarki B ali fotokemoterapijo PUVA.
English: Activation of latent polyomavirus infections that may lead to polyomavirus associated nephropathy (PVAN), especially to BK virus nephropathy (BKVN), or to JC virus associated progressive multifocal leukoencephalopathy (PML), have been observed in patients receiving ciclosporin.
Slovenian: Pri bolnikih, ki so prejemali ciklosporin, so opažali aktivacijo latentne okužbe s poliomavirusom, ki lahko povzroča s poliomavirusom povezano nefropatijo (Polyomavirus associated nephropathy - PVAN), in zlasti z virusom BK povezano nefropatijo (BK virus nephropathy - BKVN) ali z virusom JC povezano progresivno multifokalno levkoencefalopatijo (progressive multifocal leukoencephalopathy - PML).
English: The ethanol content of the Sandimmun formulations should also be taken into account in pregnant women (see section 4.4).
Slovenian: Pri uporabi zdravila pri nosečnicah je treba upoštevati tudi vsebnost etanola v formulaciji zdravila Sandimmun (glejte poglavje 4.4).
English: • how well your liver and kidneys are working,
Slovenian: • delovanje jeter in ledvic,
English: The concentrate should be diluted 1:20 to 1:100 with normal saline or 5% glucose, and given as a slow intravenous infusion over approximately 2 to 6 hours.
Slovenian: Koncentrat je treba razredčiti v fiziološki raztopini ali v 5-odstotni raztopini glukoze v razmerju 1:20 do 1:100 in aplicirati s počasno intravensko infuzijo, ki traja od 2 do 6 ur.
English: Capsule content Ethanol anhydrous Maize oil interesterified Maize oil refined
Slovenian: Vsebina kapsule brezvodni etanol interesterificirano koruzno olje rafinirano koruzno olje
English: Such diseases include eye problems which threaten your vision (endogenous uveitis, including Behçet's uveitis), severe cases of certain skin diseases (atopic dermatitis, or eczema and psoriasis), severe rheumatoid arthritis and a kidney disease called nephrotic syndrome.
Slovenian: Take avtoimunske bolezni so očesna bolezen, ki ogroža vid (endogeni uveitis, vključno z uveitisom pri Behcetovem sindromu), hude oblike določenih kožnih bolezni (atopijski dermatitis ali ekcem in psoriaza
English: • if you develop high blood pressure.
Slovenian: • če se vam zviša krvni tlak.
English: Ciclosporin is an inhibitor of CYP3A4, the multidrug efflux transporter P-glycoprotein (P-gp) and organic anion transporter proteins (OATP).
Slovenian: Ciklosporin je zaviralec CYP3A4, efluksnega prenašalca za več zdravil P-glikoproteina (P-gp) in organskega anionskega prenašalnega polipeptida (angl. organic anion-transporting polypeptide
English: Sandimmun treatment should be initiated by physicians with experience in the diagnosis and treatment of psoriasis.
Slovenian: Zdravljenje z zdravilom Sandimmun lahko uvede samo zdravnik, ki ima izkušnje z diagnostiko in zdravljenjem psoriaze.
English: If you are not sure, talk to your doctor or pharmacist before taking Sandimmun.
Slovenian: Če ste negotovi, se pogovorite s svojim zdravnikom ali farmacevtom, preden začnete jemati zdravilo Sandimmun.
English: • High level of uric acid or potassium in your blood, low levels of magnesium in your blood.
Slovenian: • zvišana raven sečne kisline ali kalija v krvi, znižana raven magnezija v krvi
English: The concurrent administration of nifedipine with ciclosporin may result in an increased rate of gingival hyperplasia compared with that observed when ciclosporin is given alone.
Slovenian: Pri sočasni uporabi nifedipina in ciklosporina lahko pride do povečane pogostnosti hiperplazije dlesni v primerjavi z njeno pogostnostjo pri samostojni uporabi ciklosporina.
English: For the first 6 weeks of treatment the recommended dose is 3 mg/kg/day orally given in 2 divided doses.
Slovenian: Revmatoidni artritis Za prvih 6 tednov zdravljenja je priporočeni odmerek 3 mg/kg/dan peroralno, in sicer v dveh deljenih odmerkih.
English: If the effect is insufficient, the daily dose may then be increased gradually as tolerability permits, but should not exceed 5 mg/kg.
Slovenian: Če učinek ni zadosten, je mogoče dnevni odmerek postopoma zvišati, če ga bolnik dobro prenaša, vendar najvišji odmerek ne sme preseči 5 mg/kg.
English: For volume greater than 1 ml, use the 4-ml syringe.
Slovenian: Če morate odmeriti volumen, ki je večji od 1 ml, uporabite 4-mililitrsko brizgo.
English: At toxic doses (rats at 30 mg/kg/day and rabbits at 100 mg/kg/day orally), ciclosporin was embryo- and foetotoxic as indicated by increased prenatal and postnatal mortality, and reduced foetal weight together with related skeletal retardations.
Slovenian: (peroralno 30 mg/kg/dan pri podganah in 100 mg/kg/dan pri kuncih) je ciklosporin toksično deloval na zarodek in plod, kar se je odražalo s povečano prenatalno in postnatalno umrljivostjo ter z zmanjšanjem plodovemase, skupaj z zastojem v rasti in razvoju skeleta.
English: • The 1 ml syringe is used to measure doses of 1 ml or smaller.
Slovenian: • 1-mililitrska brizga je namenjena odmerjanju volumnov, ki so manjši ali enaki 1 ml.