FrancophonIA/ELRC3.0 huggingface dataset:
English: 3rd occurrence of QTc>500 ms during treatment and change from pre-treatment value remains <60 ms
Slovenian: 3. pojav intervala QTc > 500 ms med zdravljenjem, sprememba intervala pa ostane < 60 ms od vrednosti pred zdravljenjem
English: 1st occurrence of QTc>500 ms during treatment and change from pre-treatment value remains <60 ms
Slovenian: 1. pojav intervala QTc > 500 ms med zdravljenjem, sprememba intervala pa ostane < 60 ms od vrednosti pred zdravljenjem
English: ● Inflammation of hair's roots
Slovenian: • vnetje lasnih vršičkov,
English: Hepatobiliary disorders
Slovenian: Dupuytrenova kontraktura
English: How to store Zelboraf
Slovenian: , zvišan bilirubin
English: February 01, 2012 data cut-off date (z) Progression-free survival Hazard Ratio (95% CI)
Slovenian: Celokupni odziv (95-% interval zaupanja) Preživetje brez napredovanja bolezni Razmerje ogroženosti (95-% interval zaupanja) Število dogodkov (%) Mediana preživetja brez napredovanja bolezni (meseci) (95-% interval zaupanja) Podatki, zbrani do 1. februarja 2012
English: Eye disorders
Slovenian: Bolezni oči
English: Common (may affect up to 1 in 10 people):
Slovenian: Pogosti neželeni učinki (pojavijo se lahko pri največ 1 od 10 bolnikov):
English: ● Back pain
Slovenian: • bolečine v hrbtu,
English: What Zelboraf looks like and contents of the pack Zelboraf 240 mg film-coated tablets are pinkish white to orange white.
Slovenian: Zdravilo Zelboraf 240 mg filmsko obložene tablete so rožnatobele do oranžnobele tablete, ovalne oblike in z vtisnjeno oznako "VEM" na eni strani.
English: ● Headache
Slovenian: • glavobol,
English: pruritus, vomiting, skin papilloma and hyperkeratosis.
Slovenian: Bolezni jeter, žolčnika in žolčevodov poškodba jeter
English: Dermatologic reactions
Slovenian: Kožne reakcije
English: METHOD AND ROUTE(S) OF ADMINISTRATION Read the package leaflet before use Oral use
Slovenian: POSTOPEK IN POT(I) UPORABE ZDRAVILA peroralna uporaba
English: Grade 4 1st occurrence of any grade 4 AE Discontinue permanently or interrupt vemurafenib treatment until grade 0 - 1.
Slovenian: Dokončno prenehajte z zdravljenjem ali ga prekinite, dokler se neželeni dogodek ne zniža na stopnjo 0 do 1.
English: Cutaneous squamous cell carcinoma (d) (cuSCC)
Slovenian: • sindrom roka-noga (t.j.
English: Talc
Slovenian: WT
English: Pancreatitis has been reported in vemurafenib-treated subjects.
Slovenian: Pri bolnikih, zdravljenih z zdravilom Zelboraf, so poročali o pankreatitisu.
English: This is especially important if you are taking:
Slovenian: To je še posebej pomembno, če jemljete:
English: The mechanism for this increased risk is not known.
Slovenian: Mehanizem tega večjega tveganja ni znan.
English: Active Control (a)
Slovenian: Aktivna kontrola (a)
English: This is because alcohol will have an additive negative effect.
Slovenian: Alkohol ima namreč dodaten negativen učinek.
English: Hypotension and circulatory collapse should be treated with appropriate measures.
Slovenian: Hipotenzijo in cirkulatorni kolaps je treba zdraviti z ustreznimi ukrepi.
English: N is number of subjects.
Slovenian: N pomeni število udeležencev.
English: Patients should be closely monitored during this period.
Slovenian: V tem obdobju je treba bolnike skrbno nadzirati.
English: Dose adjustment due to interactions
Slovenian: Prilagoditev odmerka zaradi interakcij
English: However, the primary and key secondary efficacy endpoints were not met in younger patients (below 15 years of age).
Slovenian: Kljub temu pa primarni in glavni sekundarni cilji študije učinkovitosti niso bili izpolnjeni pri mlajših bolnikih (mlajših od 15 let).
English: • medicines that lower blood pressure, as this medicine can also lower blood pressure
Slovenian: • zdravila za zniževanje krvnega tlaka, saj lahko tudi to zdravilo zniža krvni tlak.
English: Overall mortality
Slovenian: Celokupna umrljivost
English: Study Statistic
Slovenian: Statistika študije
English: • sudden death associated with heart disease.
Slovenian: • nenadna smrt, ki je posledica bolezni srca.
English: The safety and efficacy of lurasidone in children aged less than 18 years have not been established.
Slovenian: Varnost in učinkovitost lurasidona pri otrocih, mlajših od 18 let, nista bili dokazani.
English: Date of latest renewal: 14 November 2018
Slovenian: Datum prve pridobitve: 21. marec 2014 Datum zadnjega podaljšanja: 14. november 2018
English: This medicine is not recommended for children and adolescents under 18 years due to the lack of data in these patients.
Slovenian: Uporaba tega zdravila pri otrocih in mladostnikih, mlajših od 18 let, zaradi pomanjkanja podatkov ni priporočljiva.
English: This difference neared, but did not reach, statistical significance.
Slovenian: Ta razlika je bila blizu kriterija statistične značilnosti, vendar pa ga ni dosegla.
English: • reduced appetite
Slovenian: • zmanjšanje apetita
English: Lurasidone should not be used during pregnancy unless clearly necessary.
Slovenian: Lurasidona se ne sme uporabljati med nosečnostjo, če to ni nujno potrebno.
English: If your doctor decides that the potential benefit of treatment during pregnancy justifies the potential risk to your unborn baby, your doctor will monitor your baby closely after birth.
Slovenian: Če zdravnik presodi, da možna korist zdravljenja med nosečnostjo upravičuje možno tveganje za nerojenega otroka, bo zdravnik otroka po rojstvu skrbno nadziral.
English: Current available data are described in section 5.1 and 5.2, but no recommendation on a posology can be made.
Slovenian: Trenutno razpoložljivi podatki so opisani v poglavju 5.1 in 5.2, vendar pa priporočil za odmerjanje ne moremo podati.
English: ****ADRs noted in Phase 2 and 3 controlled and uncontrolled studies; however, the incidence of occurrence for these are too low to estimate frequencies.
Slovenian: ****Neželeni učinki, opaženi v nadzorovanih in nenadzorovanih študijah 2. in 3. faze, njihova pojavnost pa je bila premajhna za določitev pogostnosti.
English: Do not drive or use any tools or machines until you know that this medicine does not affect you in a negative way.
Slovenian: Ne vozite vozil in ne upravljajte z orodji ali s stroji, dokler niste povsem prepričani, da to zdravilo pri vas nima tovrstnih negativnih vplivov.
English: Frequency not known
Slovenian: Pogostnost neznana
English: • increased blood pressure
Slovenian: • zvišanje krvnega tlaka
English: What Latuda is and what it is used for
Slovenian: Kaj je zdravilo Latuda in za kaj ga uporabljamo
English: These could be symptoms of a condition known as neuroleptic malignant syndrome.
Slovenian: To so lahko simptomi stanja, poznanega kot maligni nevroleptični sindrom.
English: If you stop taking this medicine you will lose the effects of the medicine.
Slovenian: Če prenehate jemati to zdravilo, bodo učinki zdravila izzveneli.
English: Patient should be advised to seek medical attention if they experience any signs and symptoms.
Slovenian: Bolnikom je treba svetovati, naj poiščejo zdravniško pomoč, če se jim pojavijo kakršni koli znaki in simptomi.
English: Efficacy was also confirmed in a secondary analysis of treatment response (defined as ≥ 30% decrease from Baseline in PANSS
Slovenian: Učinkovitost so potrdili tudi pri sekundarni analizi odziva na zdravljenje (opredeljen kot zmanjšanje skupne ocene po PANSS od izhodišča za ≥ 30 %).
English: • are allergic to lurasidone or any of the other ingredients of this medicine (listed in section 6)
Slovenian: • če ste alergični na lurasidon ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
English: Cardiovascular monitoring should commence immediately, including continuous electrocardiographic monitoring for possible arrhythmias.
Slovenian: Nemudoma je treba začeti spremljati delovanje srca in ožilja, vključno s kontinuiranim elektrokardiografskim nadzorom možnih aritmij.
English: • painful or absence of menstrual periods
Slovenian: • boleča menstruacija ali izostanek menstruacije
English: • if you are taking some other medicines (see section 2, Other medicines and Latuda)
Slovenian: • zdravljenja z nekaterimi drugimi zdravili (glejte poglavje 2, Druga zdravila in zdravilo Latuda).
English: • problems with erections
Slovenian: • težave z erekcijo
English: The recommended starting dose is 18.5 mg.
Slovenian: Priporočeni začetni odmerek je 18,5 mg.
English: If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before taking this medicine.
Slovenian: Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, preden vzamete to zdravilo.
English: • feeling of restlessness and inability to sit still • sleepiness.
Slovenian: • občutek nemira in nezmožnost mirnega sedenja.
English: Анджелини Фарма България ЕООД бул.
Slovenian: Bulgaria/ България Анджелини Фарма България ЕООД бул.
English: Pharmacokinetics in special patient groups:
Slovenian: Farmakokinetika pri posebnih skupinah bolnikov
English: Patients should be cautioned about operating hazardous machines, including motor vehicles, until they are reasonably certain that lurasidone does not affect them adversely (see section 4.8).
Slovenian: Bolnike je treba opozoriti, da morajo biti pri upravljanju z nevarnimi stroji, vključno z vožnjo motornih vozil, previdni, dokler niso povsem prepričani, da lurasidon pri njih nima tovrstnih neželenih učinkov (glejte poglavje 4.8).
English: Dopamine and serotonin are neurotransmitters (substances that allow nerve cells to communicate with each other) that are involved in the symptoms of schizophrenia.
Slovenian: Dopamin in serotonin sta živčna prenašalca (spojine, ki omogočajo komunikacijo med živčnimi celicami), ki sta vpletena v simptome shizofrenije.
English: Lurasidone has minor influence on the ability to drive and use machines.
Slovenian: Lurasidon ima blag vpliv na sposobnost vožnje in upravljanja strojev.
English: • The active substance is lurasidone.
Slovenian: • Učinkovina je lurasidon.
English: • medicines for Parkinson's disease and restless legs syndrome (e.g. levodopa) as this medicine can reduce their effects
Slovenian: • zdravila za zdravljenje Parkinsonove bolezni in sindroma nemirnih nog (npr. levodopa), ker lahko to zdravilo zmanjša njihov učinek
English: For all other doses patients can be restarted on their previous dose without need for up-titration.
Slovenian: Pri vseh ostalih odmerkih lahko bolniki zdravljenje ponovno začnejo s predhodnim odmerkom brez titracije odmerka.
English: An increased risk cannot be excluded for other antipsychotics or other patient populations.
Slovenian: Pri uporabi drugih antipsihotikov ali v drugih populacijah bolnikov večjega tveganja ni mogoče izključiti.
English: Grapefruit can affect the way this medicine works.
Slovenian: Grenivka lahko vpliva na delovanje tega zdravila.
English: Patients on doses higher than 111 mg once daily who discontinue their treatment for longer than 3 days should be restarted on 111 mg once daily and up-titrated to their optimal dose.
Slovenian: Pri bolnikih, ki se zdravijo z odmerki, večjimi od 111 mg enkrat na dan, in zdravljenje prekinejo za več kot 3 dni, je treba zdravljenje zopet uvesti v odmerku 111 mg enkrat na dan, nato pa odmerek titrirati do njihovega optimalnega odmerka.
English: In the short-term studies there was no consistent dose-response correlation observed.
Slovenian: V kratkoročnih študijah niso opazili konsistentne soodvisnosti med odmerkom in odzivom.
English: Subjects with ESRD (CrCl<15 ml/min) have not been investigated.
Slovenian: Oseb s končno ledvično odpovedjo (CrCl < 15 ml/min) niso raziskovali.
English: Animal studies are insufficient with respect to effects on pregnancy, embryonal/foetal development, parturition and postnatal development (see section 5.3).
Slovenian: Ni dovolj študij na živalih o vplivu zdravila na nosečnost, razvoj zarodka/plodu, porod in postnatalni razvoj (glejte poglavje 5.3).
English: The recommended starting dose is 37 mg once a day.
Slovenian: Priporočeni začetni odmerek je 37 mg enkrat na dan.
English: These prolactin-related effects are not considered to be relevant to human reproduction.
Slovenian: Ti s prolaktinom povezani učinki niso pomembni za razmnoževanje pri človeku.
English: The European Medicines Agency has deferred the obligation to submit the results of studies with lurasidone in one or more subsets of the paediatric population in schizophrenia (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z lurasidonom za eno ali več podskupin pediatrične populacije s shizofrenijo (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: If signs and symptoms of tardive dyskinesia appear, the discontinuation of all antipsychotics, including lurasidone, should be considered.
Slovenian: Če se pojavijo znaki in simptomi tardivne diskinezije, je treba razmisliti o ukinitvi zdravljenja z vsemi antipsihotiki, vključno z lurasidonom.
English: Dystonia: Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible individuals during the first few days of treatment.
Slovenian: Distonija: Simptomi distonije, dolgotrajnega nenormalnega krčenja mišičnih skupin, se lahko v prvih nekaj dneh zdravljenja pojavijo pri občutljivih posameznikih.
English: -5.7 (1.39; -8.4 to -3.0)
Slovenian: -5,7 (1,39; od -8,4 do p-vrednost
English: Studies in animals have shown a number of effects on fertility, mainly related to prolactin increase, which are not considered to be relevant to human reproduction (see section 5.3).
Slovenian: Študije na živalih so pokazale številne učinke na plodnost, predvsem v zvezi z zvišanjem vrednosti prolaktina, ki pa niso pomembne za razmnoževanje pri človeku (glejte poglavje 5.3).
English: • amprenavir, efavirenz, etravirine (to treat HIV infection)
Slovenian: • amprenavir, efavirenz, etravirin (za zdravljenje okužbe z virusom HIV)
English: The following terms and frequencies are applied: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1000 to < 1/100), rare (≥ 1/10,000 to < 1/1000), very rare (<1 /10,000) and not known (cannot be estimated from the available data).
Slovenian: Kategorije pogostnosti so navedene v skladu z naslednjim dogovorom: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1 /10.000) in neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: You should not stop this medicine unless told to do so by your doctor as your symptoms may return.
Slovenian: Zdravila ne smete nehati jemati, razen če vam tako svetuje zdravnik, ker se simptomi bolezni lahko ponovijo.
English: If you notice any of the following symptoms seek medical attention immediately:
Slovenian: Če opazite katerega koli od naslednjih simptomov, nemudoma poiščite zdravniško pomoč:
English: Other medicines and Latuda
Slovenian: Druga zdravila in zdravilo Latuda
English: • Suicidal thoughts or behaviour
Slovenian: • če imate samomorilne misli ali samomorilno vedenje
English: Dosing recommendations for elderly patients with normal renal function (CrCl ≥ 80 ml/min) are the same as for adults with normal renal function.
Slovenian: Priporočila za odmerjanje pri starostnikih z normalnim delovanjem ledvic (CrCl ≥ 80 ml/min) so enaka kot pri odraslih z normalnim delovanjem ledvic.
English: The major biotransformation pathways are oxidative N-dealkylation, hydroxylation of norbornane ring, and S-oxidation.
Slovenian: Glavne poti biotransformacije so oksidativna N-dealkilacija, hidroksilacija norbornan obroča in S-oksidacija.
English: There was no clear correlation between obtained plasma exposure and age or body weight.
Slovenian: Soodvisnost med doseženo plazemsko izpostavljenostjo in starostjo ali telesno maso ni bila jasna.
English: If you miss one dose, take your next dose on the day after the missed dose.
Slovenian: Če ste pozabili vzeti en odmerek, vzemite naslednji odmerek naslednji dan.
English: An elevated risk of acute dystonia is observed in males and younger age groups.
Slovenian: Večje tveganje za akutno distonijo so opazili pri moških in mlajših starostnih skupinah.
English: The pharmacokinetics of lurasidone in paediatric patients was investigated in 49 children aged 6-12 years and 56 adolescents aged 13-17 years.
Slovenian: Pri pediatričnih bolnikih so farmakokinetiko lurasidona raziskali pri 49 otrocih, starih od 6 do 12 let, in 56 mladostnikih, starih od 13 do 17 let.
English: Lurasidone showed significant separation from placebo from as early as Day 4.
Slovenian: Lurasidon se je pomembno razlikoval od placeba že od 4. dneva dalje.
English: The maximum daily dose should not exceed 148 mg.
Slovenian: Največji dnevni odmerek ne sme preseči 148 mg.
English: • dry mouth or excess saliva
Slovenian: • suha usta ali čezmerno izločanje sline
English: Given the primary central nervous system effects of lurasidone, lurasidone should be used with caution in combination with other centrally acting medicinal products and alcohol.
Slovenian: Glede na primarno delovanje lurasidona na osrednje živčevje, je lurasidon treba uporabljati previdno v kombinaciji z drugimi centralno delujočimi zdravili in z alkoholom.
English: Orthostatic hypotension/syncope
Slovenian: Ortostatska hipotenzija/sinkopa
English: In that study the rate of relapse over a 12-month period was 20% for lurasidone and 16% for risperidone.
Slovenian: V tej študiji je delež ponovitev po 12-mesečnem obdobju za lurasidon znašal 20 %, za risperidon pa 16 %.
English: While these symptoms can occur at low doses, they occur more frequently and with greater severity, higher potency and at higher doses of first generation antipsychotic medicinal products.
Slovenian: Ti simptomi se lahko pojavijo že pri majhnih odmerkih, vendar pa so pogostejši in močnejši pri antipsihotikih prve generacije.
English: However, because elderly patients may have diminished renal function, dose adjustments may be required according to their renal function status (see “Renal impairment” below).
Slovenian: Ker pa je pri starostnikih delovanje ledvic lahko slabše, bo pri njih odmerek morda treba prilagoditi glede na stanje delovanja ledvic (glejte “Okvara ledvic” v nadaljevanju).
English: • gas (flatulence)
Slovenian: • vetrovi (flatulenca)
English: The following side effects may also happen:
Slovenian: Možni neželeni učinki so še:
English: • problems walking
Slovenian: • težave s hojo
English: If you miss two or more doses, contact your doctor.
Slovenian: Če ste izpustili dva ali več odmerkov, se posvetujte z zdravnikom.
English: Lurasidone does not impact concentrations of lithium.
Slovenian: Lurasidon ne vpliva koncentracije litija.
English: Hypertension Hypotension Orthostatic hypotension Hot flush Blood pressure increased
Slovenian: Žilne bolezni hipertenzija hipotenzija ortostatska hipotenzija vročinski oblivi zvišan krvni tlak
English: -0.44 (0.112; -0.66 to -0.22)
Slovenian: -0,44 (0,112; od -0,66 do p-vrednost
English: If taken without food, it is anticipated that lurasidone exposure will be significantly lower as compared to when taken with food (see section 5.2).
Slovenian: Pri jemanju zdravila brez hrane je pričakovana izpostavljenost lurasidonu pomembno manjša kot pri jemanju skupaj s hrano (glejte poglavje 5.2).
English: This medicine is used to improve your symptoms of schizophrenia.
Slovenian: To zdravilo izboljša simptome shizofrenije.
English: • increase in eosinophils (a type of white blood cell).
Slovenian: • zvišanje števila eozinofilcev (vrsta belih krvnih celic)
English: Lurasidone also exhibits partial agonism at the 5HT-1A receptor with a binding affinity of 6.38 nM. Lurasidone does not bind to histaminergic or muscarinic receptors.
Slovenian: Lurasidon kaže tudi delni agonizem za receptorje 5HT-1A z vezavno afiniteto 6,38 nM. Lurasidon se ne veže na histaminergične ali muskarinske receptorje.
English: Adrenaline and dopamine should not be used, or other sympathomimetics with beta agonist activity, since beta stimulation may worsen hypotension in the setting of lurasidone-induced alpha blockade.
Slovenian: Adrenalina in dopamina ali drugih simpatikomimetikov z beta agonističnim delovanjem se ne sme uporabljati, saj lahko beta stimulacija v pogojih z lurasidonom povzročene alfa blokade poslabša hipotenzijo.
English: A persistent effect of posaconazole on lurasidone exposure was observed up to 2-3 weeks after stop of posaconazole co-administration.
Slovenian: Vztrajni učinek posakonazola na izpostavljenost lurasidonu so opazili do 2-3 tedne po prekinitvi sočasne uporabe posakonazola.
English: Clinical monitoring of weight is recommended.
Slovenian: Priporoča se klinično spremljanje telesne mase.
English: You should not take this medicine during pregnancy unless this has been agreed with your doctor.
Slovenian: Med nosečnostjo tega zdravila ne smete jemati, razen če vam tako svetuje zdravnik.
English: Your dose will be decided by your doctor and may depend on:
Slovenian: Odmerek je lahko odvisen od:
English: By blocking their receptors, lurasidone helps to normalise the activity of the brain, reducing the symptoms of schizophrenia.
Slovenian: Lurasidon z zaviranjem njunih receptorjev pomaga normalizirati delovanje možganov in zmanjša simptome shizofrenije.
English: • armodafinil, modafinil (to treat sleepiness)
Slovenian: • armodafinil, modafinil (za zdravljenje pretirane zaspanosti)
English: The safety of lurasidone has been evaluated at doses of 18.5 -148 mg in clinical studies in patients with schizophrenia treated for up to 52 weeks and in the post-marketing setting.
Slovenian: Varnost lurasidona v odmerkih od 18,5 do 148 mg so ovrednotili v kliničnih študijah pri bolnikih s shizofrenijo, ki so se zdravili do 52 tednov, in v obdobju trženja zdravila.
English: The dose may be increased or decreased by your doctor within the dose range of 18.5 mg to 148 mg once a day.
Slovenian: Zdravnik lahko odmerek poveča ali zmanjša v razponu odmerkov od 18,5 do 148 mg enkrat na dan.
English: Following administration of 37 mg of lurasidone, the mean approximate apparent volume of distribution was 6000 L. Lurasidone is highly bound (~99%) to serum proteins.
Slovenian: Pri uporabi 37 mg lurasidona je povprečni približni navidezni volumen porazdelitve znašal 6.000 l. Lurasidon se obsežno veže (~99 %) na beljakovine v serumu.
English: In patients with moderate (Creatinine Clearance (CrCl) ≥ 30 and < 50 ml/min), severe renal impairment (CrCL >15 and < 30 ml/min) and End Stage Renal Disease (ESRD) patients (CrCl < 15 ml/min), the recommended starting dose is 18.5 mg and the maximum dose should not exceed 74 mg once daily.
Slovenian: Priporočeni začetni odmerek pri bolnikih z zmerno (kreatininski očistek (CrCl) ≥ 30 in < 50 ml/min) in s hudo okvaro ledvic (CrCl > 15 in < 30 ml/min) ter bolnikih s končno ledvično odpovedjo (CrCl < 15 ml/min) je 18,5 mg, največji dnevni odmerek pa ne sme preseči 74 mg enkrat na dan.
English: Following oral administration of a radiolabelled dose, approximately 67% dose was recovered in faeces and 19% in urine.
Slovenian: Po peroralni uporabi z radioaktivnim izotopom označenega odmerka se je približno 67 % radioaktivnosti izločilo z blatom, 19 % pa z urinom.
English: Lurasidone was excreted in milk of rats during lactation.
Slovenian: Lurasidon se je izločal v mleko podgan v času laktacije.
English: Potential for lurasidone to affect other medicinal products
Slovenian: Možen vpliv lurasidona na delovanje drugih zdravil
English: Hungary/ Magyarország Angelini Pharma Magyarország Kft Dayka Gábor u. 3., 214-215. számú iroda
Slovenian: Hungary/ Magyarország Angelini Pharma Magyarország Kft Dayka Gábor u. 3., 214-215. számú iroda H-1118 Budapest
English: The following medicines may decrease the level of lurasidone in your blood:
Slovenian: Naslednja zdravila lahko zmanjšajo nivo lurasidona v krvi:
English: Lurasidone may cause orthostatic hypotension, perhaps due to its α1-adrenergic receptor antagonism.
Slovenian: Lurasidon lahko povzroči ortostatsko hipotenzijo, morda zaradi antagonističnega delovanja na α1-adrenergične receptorje.
English: Prins Bernhardplein 200 1097 JB Amsterdam, Netherlands med.infoeu@sunovion.com
Slovenian: 1097 JB Amsterdam, Netherlands med.infoeu@sunovion.com