FrancophonIA/ELRC3.0 huggingface dataset:
English: Use of filgrastim in patients with HIV infection maintains normal neutrophil counts to allow scheduled dosing of antiviral and/or other myelosuppressive medicinal product.
Slovenian: Uporaba filgrastima pri bolnikih z okužbo HIV pomaga ohranjati število nevtrofilcev ter tako omogoča predvideno odmerjanje antivirusnih in/ali drugih mielosupresivnih zdravil.
English: In some SCN patients, filgrastim can also induce a minor increase in the number of circulating eosinophils and basophils relative to baseline; some of these patients may present with eosinophilia or basophilia prior to treatment.
Slovenian: Pri nekaterih bolnikih s hudo kronično nevtropenijo lahko filgrastim sproži rahlo povečanje eozinofilcev in bazofilcev v obtoku; pri nekaterih izmed teh bolnikov je pred zdravljenjem opaziti eozinofilijo ali bazofilijo.
English: Long-term daily administration is required to maintain an adequate neutrophil count.
Slovenian: Dolgotrajno dnevno odmerjanje je potrebno za vzdrževanje števila nevtrofilcev na primerni ravni.
English: In cancer patients
Slovenian: Bolniki z rakom
English: Acute grade II-IV GvHD
Slovenian: Akutna GvHD stopnje II-IV
English: Filgrastim acts primarily on neutrophil precursors to exert its effect in elevating neutrophil counts.
Slovenian: Filgrastim deluje v glavnem na prekurzorje za nevtrofilce, ki vplivajo na povišanje števila nevtrofilcev.
English: cell numbers vary depending on the precise methodology used and therefore, recommendations of numbers based on studies in other laboratories need to be interpreted with caution.
Slovenian: Izidi pretočne citometrične analize števila celic CD34+ se spreminjajo glede na uporabljeno metodologijo, zaradi česar moramo biti pri vrednotenju priporočil o številu, ki temeljijo na različnih raziskavah iz drugih laboratorijev, previdni.
English: In cancer patients, the pharmacokinetic profile of Biograstim and the reference product was comparable after single and repeated subcutaneous administration.
Slovenian: Pri bolnikih z rakom sta bila farmakokinetična profila zdravila Biograstim in referenčnega zdravila primerljiva po enkratnem in ponavljajočem odmerku, ki so ga bolniki prejeli po subkutani poti.
English: The safety and efficacy of filgrastim given on the same day as myelosuppressive cytotoxic chemotherapy have not been definitively established.
Slovenian: Varnost in učinkovitost filgrastima, ki ga bolnik prejme na isti dan kot mielosupresivno citotoksično kemoterapijo, nista bili natančno ugotovljeni.
English: MDS and leukaemias are natural complications of the disease and are of uncertain relation to filgrastim therapy.
Slovenian: Mielodisplatični sindrom in levkemija sta običajna zapleta pri bolezni in ju ne moremo z gotovostjo povezati z zdravljenjem s filgrastimom.
English: Undesirable effects reported with equal frequency in patients treated with filgrastim/chemotherapy and placebo/chemotherapy included nausea and vomiting, alopecia, diarrhoea, fatigue, anorexia, mucositis, headache, cough, skin rash, chest pain, generalised weakness, sore throat, constipation and unspecified pain.
Slovenian: Med neželenimi učinki, o katerih so enako pogosto poročali bolniki, zdravljeni s filgrastimom/kemoterapijo in placebom/kemoterapijo, so bili slabost in bruhanje, alopecija, diareja, utrujenost, anoreksija, vnetje sluznice, glavobol, kašelj, izpuščaj na koži, bolečina v prsih, splošna oslabelost, vneto grlo, zaprtje in nespecifična bolečina.
English: Mobilisation of PBPC does not provide a direct clinical benefit to normal donors and should only be considered for the purposes of allogeneic stem cell transplantation.
Slovenian: Zbiranje matičnih celic iz periferne krvi nima neposredne klinične koristi za običajne darovalce, zato je potrebno o tem razmisliti samo v primeru alogenske presaditve izvornih celic.
English: PARTICULARS TO APPEAR ON THE INTERMEDIATE PACKAGING Multipack Carton - Without Blue Box
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA VMESNI OVOJNINI Skupno pakiranje - brez podatkov »Blue Box«
English: Other undesirable effects seen include splenic enlargement, which may be progressive in a minority of cases and thrombocytopenia.
Slovenian: Med drugimi neželenimi učinki so opazili povečanje vranice, ki je v manjšem številu primerov lahko progresivno, ter trombocitopenijo.
English: Neutropenia may be due to bone marrow infiltrating opportunistic infections such as Mycobacterium avium complex or malignancies such as lymphoma.
Slovenian: Nevtropenija je lahko posledica infiltracije kostnega mozga z oportunistično okužbo z Mycobacterium avium kompleksom ali maligno boleznijo, kot je limfom.
English: In a separate retrospective international study in patients with acute and chronic myelogenous leukaemias, no effect on the risk of GvHD, TRM and mortality was seen.
Slovenian: V ločeni retrospektivni mednarodni študiji pri bolnikih z akutnimi in kroničnimi mielogenimi levkemijami niso opazili tveganja za GvHD, TRM in smrtnost.
English: Reversible, dose-dependent and usually mild or moderate elevations of lactate dehydrogenase (LDH), alkaline phosphatase, serum uric acid and gamma-glutamyltransferase (GGT) occurred with filgrastim in approximately 50 %, 35 %, 25 %, and 10 % of patients respectively, at recommended doses.
Slovenian: Reverzibilno, od odmerka odvisno blago do zmerno zvišanje laktatne dehidrogenaze (LDH), alkalne fosfataze, sečne kisline in gama-glutamiltransferaze (GGT) se je pojavilo pri 50 %, 35 %, 25 % in 10 % bolnikov, ki so prejemali filgrastim v priporočenem odmerku.
English: - The safety device prevents needle stick injuries after use, so no special precautions for disposal are required.
Slovenian: Odlaganje rabljenih injekcijskih brizg - Varnostni pripomoček preprečuje poškodbe zaradi vboda z iglo po uporabi, tako da za odstranjevanje niso potrebni nobeni previdnostni ukrepi.
English: Physicians should exercise caution when considering the use of filgrastim in patients with sickle cell disease and only after careful evaluation of the potential risks and benefits.
Slovenian: Zdravniki morajo biti pri predpisovanju filgrastima izredno previdni, ko gre za bolnike s srpasto anemijo, in se lahko zanj odločijo le, ko temeljito ocenijo, kakšna tveganja in kakšne koristi to predstavlja za bolnika.
English: Filgrastim should be discontinued and appropriate treatment given in these cases.
Slovenian: V tem primeru je treba prekiniti zdravljenje s filgrastimom in poskrbeti za ustrezno zdravljenje.
English: When reversal of neutropenia has been achieved, the minimal effective dose to maintain a normal neutrophil count should be established.
Slovenian: Ko ustavimo napredovanje nevtropenije, je potrebno določiti minimalen učinkovit odmerek, s katerim bomo število nevtrofilcev ohranjali na običajni ravni.
English: Causes of transient neutropenia such as viral infections should be excluded.
Slovenian: Drugi posebni previdnostni ukrepi Potrebno je izključiti vzroke prehodne nevtropenije, kot so npr. virusne okužbe.
English: Your doctor will test your blood at regular intervals to see how well the treatment is working.
Slovenian: Zdravnik vam bo redno analiziral kri, zato da ugotovi, kako dobro deluje zdravljenje.
English: The dosage recommendations in paediatric patients are the same as those in adults receiving myelosuppressive cytotoxic chemotherapy.
Slovenian: Priporočeni odmerki za pediatrične bolnike so enaki kot za odrasle osebe, ki prejemajo mielosupresivno citotoksično kemoterapijo.
English: Your doctor will continue to test your blood regularly and will recommend the best dose for you.
Slovenian: Vaš zdravnik bo še naprej analiziral vašo kri ter vam priporočil najprimernejši odmerek.
English: Do not use Biograstim in the 24 hours before or the 24 hours after your chemotherapy.
Slovenian: Zdravila Biograstim ne uporabljajte 24 ur pred kemoterapijo ali 24 ur po njej.
English: Dose reductions were noted to slow or stop the progression of splenic enlargement and in 3 % of patients a splenectomy was required.
Slovenian: Nižji odmerki so upočasnili ali ustavili povečevanje vranice, pri 3 % bolnikov pa je bila potrebna operativna odstranitev vranice.
English: For example, if you weigh 60 kg your daily dose will be 30 million international units (MIU).
Slovenian: Npr., če tehtate 60 kg, bo vaš dnevni odmerek znašal 30 milijonov mednarodnih enot (i.e.).
English: ≥ 1/10,000 to < 1/1,000
Slovenian: ≥ 1/10.000 do < 1/1000
English: After dilution: Chemical and physical in-use stability of the diluted solution for infusion has been demonstrated for 24 hours at 2 °C to 8 °C.
Slovenian: Po redčenju: razredčena raztopina za infundiranje ostane kemično in fizikalno stabilna še 24 ur pri temperaturi od 2 °C do 8 °C.
English: Continuous infusion with filgrastim over a period of up to 28 days, in patients recovering from autologous bone-marrow transplantation, resulted in no evidence of drug accumulation and comparable elimination half-lives.
Slovenian: Po neprekinjenem infundiranju filgrastima, ki je pri bolnikih, ki okrevajo po avtologni presaditvi kostnega mozga, trajalo do 28 dni, ni bilo nobenih dokazov kopičenja zdravila v telesu in primerljivih razpolovnih eliminacijskih časov.
English: Undesirable effects possibly related to filgrastim therapy and typically occurring in < 2 % of SCN patients were injection site reaction, headache, hepatomegaly, arthralgia, alopecia, osteoporosis and rash.
Slovenian: Neželeni učinki, najverjetneje povezani s terapijo s filgrastimom, ki so se značilno pojavili pri < 2 % bolnikov, so vključevali reakcijo na mestu aplikacije, glavobol, hepatomegalijo, artralgijo, alopecijo osteoporozo in izpuščaj.
English: 2/day (4.0 to 8.4 μg/kg/day) was used.
Slovenian: (230 μg)/m2/dan (4,0 do 8,4 μg/kg/dan).
English: Because of the potential of receiving higher doses of chemotherapy (e.g. full doses on the prescribed schedule) the patient may be at greater risk of thrombocytopenia and anaemia.
Slovenian: Ker obstaja možnost, da bi moral bolnik prejemati višje odmerke kemoterapije (npr. visoke odmerke glede na predpisano shemo), je bolnik lahko bolj izpostavljen tveganju za trombocitopenijo in anemijo.
English: For example, if you weigh 60 kg your daily dose will be 60 million international units (MIU).
Slovenian: Npr., če tehtate 60 kg, bo vaš dnevni odmerek znašal 60 milijonov mednarodnih enot (i.e.).
English: Data from clinical studies in paediatric patients indicate that the safety and efficacy of filgrastim are similar in both adults and children receiving cytotoxic chemotherapy.
Slovenian: Podatki iz kliničnih raziskav pri pediatričnih bolnikih so pokazali, da sta varnost in učinkovitost filgrastima pri odraslih in otrocih, ki so prejemali citotoksično kemoterapijo podobni.
English: Uncommon (may affect up to 1 in 100 people): - blood in the urine; protein in the urine.
Slovenian: Občasni (pojavijo se lahko pri največ 1 od 100 bolnikov): - kri v urinu, beljakovine v urinu.
English: To give yourself a subcutaneous injection you will need: - a pre-filled syringe of Biograstim; - alcohol wipes or similar.
Slovenian: Oprema, ki jo boste potrebovali Za subkutano samoinjiciranje boste potrebovali: - napolnjeno injekcijsko brizgo z zdravilom Biograstim, - alkoholne krpice ali podobno,
English: Not known (frequency cannot be estimated from the available data): - cough; fever and difficulty breathing or coughing up blood.
Slovenian: Neznana (pogostosti ni mogoče oceniti iz razpoložljivih podatkov): - kašelj, zvišana telesna temperatura in težave z dihanjem ali izkašljevanje krvi.
English: The effects of filgrastim on neutropenia due to bone marrow-infiltrating infection or malignancy have not been well established.
Slovenian: Učinki filgrastima na nevtropenijo zaradi infiltracije kostnega mozga z okužbo ali maligno boleznijo niso bili ugotovljeni.
English: Biograstim is useful in several different conditions, which are: - chemotherapy; - bone marrow transplantation; - severe chronic neutropenia (low white blood cell count); - neutropenia in patients with HIV infection; - peripheral blood stem cell mobilisation (for blood stem cell donation).
Slovenian: Zdravilo Biograstim pomaga pri več različnih stanjih, med katere spadajo: - kemoterapija, - presaditev kostnega mozga, - huda kronična nevtropenija (majhno število levkocitov), - nevtropenija pri bolnikih, okuženih s HIV, - zbiranje matičnih celic iz periferne krvi (za darovanje krvnih matičnih celic).
English: Discontinue filgrastim
Slovenian: Prekinite zdravljenja s filgrastimom
English: If you use more Biograstim than you should, contact your doctor or pharmacist as soon as possible.
Slovenian: Če ste uporabili večji odmerek zdravila Biograstim, kot bi smeli Če ste uporabili večji odmerek zdravila Biograstim, kot bi smeli, se čimprej posvetujte z zdravnikom ali farmacevtom.
English: Please use as follows:
Slovenian: Uporabljajte v skladu s spodnjimi navodili:
English: Use of filgrastim, either alone or after chemotherapy, mobilises haematopoietic progenitor cells into peripheral blood.
Slovenian: Uporaba filgrastima, bodisi samostojno bodisi po kemoterapiji, spodbuja zbiranje krvotvornih matičnih celic v periferni krvi.
English: There is no evidence that patients with HIV infection treated with filgrastim show an increase in HIV replication.
Slovenian: Ni dokazov, da bi pri bolnikih, okuženih s HIV, ki so prejemali filgrastim, prišlo do hitrejšega razmnoževanja virusa HIV.
English: It could be a consequence of a pulmonary disorder (see section “4.
Slovenian: Lahko gre za posledico bolezni pljuč (glejte poglavje »4.
English: You will need to have regular blood tests whilst being treated with Biograstim to count the number of neutrophils and other white blood cells in your blood.
Slovenian: Med zdravljenjem z zdravilom Biograstimvam bodo morali redno pregledovati kri, zato da naredijo analizo števila nevtrofilcev in drugih belih krvničk v vaši krvi.
English: In patients receiving cytotoxic chemotherapy, a transient increase in neutrophil counts is typically seen 1 to 2 days after initiation of filgrastim therapy.
Slovenian: Pri bolnikih, ki prejemajo citotoksično kemoterapijo, se 1. ali 2. dan po začetku zdravljenja s filgrastimom običajno pojavi začasno povečanje števila nevtrofilcev.
English: Studies of filgrastim in patients with severe impairment of renal or hepatic function demonstrate that it exhibits a similar pharmacokinetic and pharmacodynamic profile to that seen in normal individuals.
Slovenian: Raziskave v zvezi z učinkom filgrastima na bolnike s hudo okvaro ledvic ali jeter so pokazale, da ima zdravilo na te bolnike podoben farmakokinetičen in farmakodinamičen učinek kot na običajne posameznike.
English: 4.4 Special warnings and precautions for use Special warnings
Slovenian: 4.4 Posebna opozorila in previdnostni ukrepi
English: However, the administration of melphalan, carboplatin or BCNU together with filgrastim has been shown to be effective for progenitor mobilisation.
Slovenian: Če pa melfalan, karboplatin ali BCNU aplicirajo bolnikom skupaj s filgrastimom, pa ima to pozitiven učinek na zbiranje matičnih celic.
English: In view of the sensitivity of rapidly dividing myeloid cells to myelosuppressive cytotoxic chemotherapy, the use of filgrastim is not recommended in the period from 24 hours before to 24 hours after chemotherapy.
Slovenian: Zaradi možne preobčutljivosti hitro se delečih mieloidnih celic na mielosupresivno citotoksično kemoterapijo 24 ur pred in 24 ur po kemoterapiji ni priporočljivo uporaba filgrastima.
English: Biograstim is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with established cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes) and for the reduction in the duration of neutropenia in patients undergoing myeloablative therapy followed by bone marrow transplantation considered to be at increased risk of prolonged severe neutropenia.
Slovenian: Zdravilo Biograstim je indicirano za skrajšanje trajanja nevtropenije in v primeru nastanka febrilne nevtropenije pri bolnikih, ki prejemajo citotoksično kemoterapijo za maligne tvorbe (z izjemo kronične mieloične levkemije in mielodisplastičnih sindromov), ter za skrajšanje trajanja nevtropenije pri bolnikih, ki se zdravijo z mieloablativno terapijo po presaditvi kostnega mozga, pri katerih obstaja povečano tveganje za dlje trajajočo hudo nevtropenijo.
English: The safety and efficacy of filgrastim administration in patients with myelodysplastic syndrome or chronic myelogenous leukaemia have not been established.
Slovenian: Varnost in učinkovitost filgrastima nista raziskani pri bolnikih z mielodisplastičnim sindromom ali kronično mielogeno levkemijo.
English: Check the expiry date on the pre-filled syringe label (EXP).
Slovenian: Preverite datum izteka roka uporabnosti zdravila na nalepki napolnjene injekcijske brizge (Uporabno do:).
English: PBPC mobilisation should be considered only in donors who meet normal clinical and laboratory eligibility criteria for stem cell donation.
Slovenian: Za zbiranje matičnih celic iz periferne krvi se je potrebno odločiti samo pri tistih bolnikih, ki ustrezajo običajnim kliničnim in laboratorijskim kriterijem za darovanje izvornih celic.
English: One retrospective European study evaluating the use of G-CSF after allogeneic bone marrow transplantation in patients with acute leukaemias suggested an increase in the risk of GvHD, treatment related mortality (TRM) and mortality when G-CSF was administered.
Slovenian: Ena retrospektivna evropska študija, v kateri so ocenili uporabo G-CSF po alogenski presaditvi kostnega mozga pri bolnikih z akutno levkemijo, je pokazala zvišanje tveganja za GvHD, z zdravljenjem povezano smrtnostjo (TRM - treatment related mortality) in smrtnost pri uporabi G-CSF.
English: Current data indicate that immunological interactions between the allogeneic PBPC graft and the recipient may be associated with an increased risk of acute and chronic GvHD when compared with bone marrow transplantation.
Slovenian: Najnovejši podatki kažejo, da so imunološke interakcije alogenskega presadka matičnih celic iz periferne krvi in prejemnika, v primerjavi s presaditvijo kostnega mozga, lahko povezane s povečanim tveganjem akutne in kronične GvHD.
English: Capillary leak syndrome, which can be life-threatening if treatment is delayed, has been reported uncommonly (≥ 1/1000 to < 1/100) in cancer patients undergoing chemotherapy and healthy donors undergoing peripheral blood progenitor cell mobilisation following administration of G-CSFs; see section 4.4 and subsection “Description of selected adverse reactions” of section 4.8.
Slovenian: Občasno (≥ 1/1000 to < 1/100) so pri bolnikih z rakom, ki so prejemali kemoterapijo, in zdravih dajalcih, pri katerih poteka zbiranje matičnih celic iz periferne krvi, Po uporabi G-CSF poročali o sindromu kapilarne prepustnosti, ki je lahko smrtno nevaren, če ni zdravljen takoj; glejte poglavje 4.4 in podpoglavje »Opis izbranih neželenih učinkov« poglavja 4.8.
English: Biograstim containing r-metHuG-CSF (filgrastim) causes marked increases in peripheral blood neutrophil counts within 24 hours, with minor increases in monocytes.
Slovenian: Zdravilo Biograstim, ki vsebuje rekombinantni človeški G-CSF (filgrastim) v 24-ih urah povzroči izrazito zvišanje števila nevtrofilcev v periferni krvi, medtem ko je zvišanje monocitov manjše.
English: If there are air bubbles present, gently tap the syringe with your fingers until the air bubbles rise to the top of the syringe.
Slovenian: Če so v raztopini mehurčki, s prsti nežno potrkajte po brizgi, da se dvignejo na vrh brizge.
English: Biograstim should not be diluted with sodium chloride solution.
Slovenian: Zdravila Biograstim ne smemo mešati z raztopino natrijevega klorida.
English: SGOT increased, hyperuricaemia
Slovenian: Občasni zvišana SGOT, hiperurikemija
English: It is recommended to perform morphologic and cytogenetic bone marrow examinations in patients at regular intervals (approximately every 12 months).
Slovenian: Priporočajo se redne (približno vsakih 12 mesecev) morfološke in citogenetske preiskave kostnega mozga.
English: Capillary leak syndrome has been reported after G-CSF administration and is characterised by hypotension, hypoalbuminaemia, oedema and haemoconcentration.
Slovenian: Po uporabi G-CSF so poročali o sindromu kapilarne prepustnosti, za katerega so značilni hipotenzija, hipoalbuminemija, edemi in hemokoncentracija.
English: Example: In a final injection volume of 20 mL, total doses of filgrastim less than 30 MIU (300 μg) should be given with 0.2 mL of 200 mg/mL (20 %) human albumin solution added.
Slovenian: Primer: V injekciji s končnim volumnom 20 ml, morate k celotnemu odmerku filgrastima z manj kot 30 x 106 i.e. (300 μg) dodati 0,2 ml 20 % raztopine humanega albumina.
English: Do not use this medicine after the expiry date which is stated on the outer carton and on the pre-filled syringe after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na napolnjeni injekcijski brizgi poleg oznake 'uporabno do'.
English: Patients with a recent history of pulmonary infiltrates or pneumonia may be at higher risk.
Slovenian: Bolj ogroženi utegnejo biti bolniki z nedavno anamnezo pljučnih infiltratov ali pljučnice.
English: Use of filgrastim in patients undergoing cytotoxic chemotherapy leads to significant reductions in the incidence, severity and duration of neutropenia and febrile neutropenia.
Slovenian: Uporaba zdravila filgrastim pri bolnikih, ki prejemajo citotoksično kemoterapijo, izrazito zmanjša število obolevnost, ublaži resnost in skrajša trajanje nevtropenije in febrilne nevtropenije.
English: Biograstim is a clear and colourless solution.
Slovenian: Zdravilo Biograstim je bistra in brezbarvna raztopina.
English: The most commonly reported undesirable effect was mild to moderate transient musculo-skeletal pain.
Slovenian: Najbolj pogost neželen učinek, o katerem so poročali, je bila blaga do zmerna prehodna mišičnoskeletna bolečina.
English: Allergic reaction *See subsection “Description of selected adverse reactions” of section 4.8
Slovenian: *glejte podpoglavje »Opis izbranih neželenih učinkov« v poglavje 4.8.
English: A subset of approximately 12 % of patients who had normal cytogenetic evaluations at baseline was subsequently found to have abnormalities, including monosomy 7, on routine repeat evaluation.
Slovenian: Pri manjšem številu, in sicer pri 12 % bolnikov, katerih rezultati citogenetskih preiskav so bili sicer normalni, pa so pri rutinskih ponavljajočih se pregledih opazili nepravilnosti, vključno z monosomijo 7.
English: Platelet counts should be monitored closely, especially during the first few weeks of filgrastim therapy.
Slovenian: Pozorno je treba spremljati število trombocitov, še posebej prvih nekaj tednov zdravljenja s filgrastimom.
English: Premature discontinuation of filgrastim therapy prior to the time of the expected neutrophil nadir is not recommended.
Slovenian: Prezgodnja prekinitev zdravljenja s filgrastimom, preden število nevtrofilcev pade na pričakovano najnižjo raven, ni priporočljiva.
English: Remove the syringe from the injection site while keeping your finger on the plunger (see picture 7).
Slovenian: Brizga z varnostnim pripomočkom: Medtem ko prst držite na batu, injekcijsko brizgo odstranite z mesta injiciranja (glejte sliko 7).
English: The most frequent undesirable effects attributable to filgrastim were bone pain, and general musculoskeletal pain.
Slovenian: Najbolj pogosti neželeni učinki, povezani s filgrastimom, so zajemali bolečino v kosteh ter splošno mišičnoskeletno bolečino.
English: Exacerbation of rheumatoid arthritis has been observed in individual cases.
Slovenian: V posameznih primerih je prišlo do poslabšanja revmatoidnega artritisa.
English: Normal donors are given a dose of a 10 μg/kg/day, administered subcutaneously for 4 to 5 consecutive days.
Slovenian: Običajni darovalci prejmejo odmerek 10 μg/kg/dan, ki se jim odmerja po subkutani poti 4 ali 5 dni zapored.
English: Filgrastim should not be used during pregnancy unless clearly necessary.
Slovenian: Če ni nujno potrebno, se filgrastima med nosečnostjo ne sme uporabljati.