FrancophonIA/ELRC3.0 huggingface dataset:
English: If you are taking ABILIFY, your doctor will discuss with you whether you should breast-feed considering the benefit to you of your therapy and the benefit to your baby of breast-feeding.
Croatian: Ako uzimate ABILIFY, Vaš će liječnik razgovarati s Vama o tome trebate li dojiti uzimajući u obzir korist liječenja za Vas i korist dojenja za dijete.
English: • in blood tests: increased or fluctuating blood sugar, increased glycosylated haemoglobin.
Croatian: • krvne pretrage: fluktuacija šećera u krvi, povišeni glikirani hemoglobin,
English: No specific interaction studies have been performed with ABILIFY solution for injection.
Croatian: Nisu provedena posebna ispitivanja interakcija lijeka ABILIFY otopina za injekciju.
English: - uncontrollable excessive shopping
Croatian: - pretjerano kupovanje ili trošenje koje se ne može kontrolirati,
English: Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product.
Croatian: Bolesnici s rijetkim nasljednim poremećajem nepodnošenja fruktoze, malapsorpcijom glukoze i galaktoze ili insuficijencijom sukraza-izomaltaza ne bi smjeli uzimati ovaj lijek.
English: If signs and symptoms of other EPS appear in a patient taking aripiprazole, dose reduction and close clinical monitoring should be considered.
Croatian: Ako se u bolesnika koji uzimaju aripiprazol pojave znakovi i simptomi ekstrapiramidnih simptoma, treba razmotriti smanjenje doze i strog klinički nadzor.
English: Talk to your doctor before you are given ABILIFY.
Croatian: Obratite se svom liječniku prije nego što dobijete ABILIFY.
English: The total body clearance of aripiprazole is 0.7 mL/min/kg, which is primarily hepatic.
Croatian: Ukupni klirens aripiprazola iz tijela je 0,7 ml/min/kg i primarno se odvija putem jetre.
English: The dose of ABILIFY must be measured using the calibrated cup or the 2 mL calibrated dropping pipette supplied in the carton.
Croatian: Doza lijeka ABILIFY mora se odmjeriti primjenom kalibrirane čašice ili kalibrirane kapaljke od 2 ml,
English: • St John's Wort (Hypericum perforatum) used as a herbal remedy for mild depression
Croatian: • gospina trava (Hypericum perforatum) koja se primjenjuje kao biljni lijek kod blage depresije
English: When either valproate or lithium was administered concomitantly with aripiprazole, there was no clinically significant change in aripiprazole concentrations and therefore no dose adjustment is necessary when either valproate or lithium is administered with aripiprazole.
Croatian: Kad su se istodobno s aripiprazolom primjenjivali valproat ili litij nije bilo klinički značajne promjene u koncentracijama aripiprazola pa stoga nije potrebna prilagodba doze kad se valproat ili litij primjenjuju uz aripiprazol.
English: • life-threatening irregular heartbeat,
Croatian: • za život opasni nepravilni otkucaji srca,
English: • muscle disorder causing twisting movements (dystonia),
Croatian: • poremećaj mišića koji uzrokuje pokrete uvijanja (distonija),
English: Patients receiving ABILIFY solution for injection should be observed for orthostatic hypotension.
Croatian: Bolesnike koji primaju ABILIFY otopinu za injekciju mora se nadzirati zbog moguće pojave ortostatske hipotenzije.
English: Aripiprazole group showed an improvement of 14.97 on TTS-YGTSS change from baseline to week 10 as compared with an improvement of 9.62 in the placebo group.
Croatian: Skupina koja je primala aripiprazol pokazala je poboljšanje od 14,97 na ljestvici TTS-YGTSS od početne vrijednosti do one u 10. tjednu u usporedbi s poboljšanjem od 9,62 u skupini koja je primala placebo.
English: Non-clinical data reveal no special hazard for humans based on conventional oral aripiprazole studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential, toxicity to reproduction and development.
Croatian: Neklinički podaci ne ukazuju na poseban rizik za ljude na temelju konvencionalnih ispitivanja sigurnosne farmakologije, toksičnosti ponovljenih doza, genotoksičnosti, kancerogenog potencijala, reproduktivne i razvojne toksičnosti kod primjene oralnog aripiprazola.
English: The observed mean improvement from baseline on the PANSS Excitement Component score at the primary 2-hour endpoint was 5.8 for placebo, 9.6 for lorazepam, and 8.7 for ABILIFY solution for injection.
Croatian: Primijećena srednja vrijednost poboljšanja 2 sata nakon primjene, što je bilo odabrano kao primarna mjera ishoda, u odnosu na rezultat za komponentu uzbuđenosti prema ljestvici PANSS na početku ispitivanja iznosila je 5,8 za placebo, 9,6 za lorazepam i 8,7 za ABILIFY otopina za injekciju.
English: The oral solution should not be diluted with other liquids or mixed with any food prior to administration.
Croatian: Oralna otopina ne smije se razrjeđivati drugim tekućinama niti miješati s hranom prije primjene.
English: In 2 studies in healthy subjects the median times to the peak plasma concentrations were 1 and 3 hours after dosing.
Croatian: medijan vremena do postizanja vršnih koncentracija u plazmi iznosio je 1 i 3 sata nakon doziranja.
English: The safety profile of a long-term, double-blind, placebo-controlled trial was also similar except for the following reactions that were reported more frequently than paediatric patients taking placebo: weight decreased, blood insulin increased, arrhythmia, and leukopenia were reported commonly (≥ 1/100,
Croatian: Sigurnosni profil u dugotrajnom, dvostruko slijepom, placebom kontroliranom ispitivanju također je bio sličan, osim što su sljedeće nuspojave bile zabilježene češće nego u pedijatrijskih bolesnika koji su uzimali placebo: često (≥ 1/100, < 1/10) su bili zabilježeni smanjena tjelesna težina, povišen inzulin u krvi, aritmija i leukopenija.
English: In the same trials, cerebrovascular adverse reactions (e.g. stroke, transient ischaemic attack), including fatalities, were reported in patients (mean age: 84 years; range: 78 to 88 years).
Croatian: U tim istim ispitivanjima, u bolesnika (prosječna dob: 84 godine; raspon: 78 do 88 godina) su bile prijavljene cerebrovaskularne nuspojave (npr. moždani udar, tranzitorna ishemijska ataka), uključujući i smrtne slučajeve.
English: Immediately upon opening the blister, using dry hands, remove the tablet and place the entire orodispersible tablet on the tongue.
Croatian: Odmah po otvaranju blistera suhim rukama uzmite tabletu i stavite je na jezik.
English: EXP Use within 6 months after first opening.
Croatian: Rok valjanosti Upotrijebiti unutar 6 mjeseci nakon prvoga otvaranja.
English: • medicines to correct heart rhythm (such as quinidine, amiodarone, flecainide)
Croatian: • lijekove za regulaciju srčanog ritma (kao što su kinidin, amiodaron i flekainid)
English: 6 mg aspartame (E 951) and 0.225 mg lactose per orodispersible tablet
Croatian: 6 mg aspartama (E 951) i 0,225 mg laktoze po raspadljivoj tableti za usta
English: Each carton contains 1 bottle and both a calibrated polypropylene measuring cup with a graduation interval of 2.5 mL and a calibrated polypropylene low-density polyethylene dropping pipette with a graduation interval of 0.5 mL.
Croatian: Jedna kutija sadrži 1 bocu te kalibriranu polipropilensku odmjernu čašicu graduiranu na 2,5 ml i kalibriranu kapaljku od polipropilena i polietilena male gustoće graduiranu na 0,5 ml.
English: Adolescents aged 13 years and older experienced side effects that were similar in frequency and type to those in adults except that sleepiness, uncontrollable twitching or jerking movements, restlessness, and tiredness were very common (greater than 1 in 10 patients) and upper abdominal pain, dry mouth, increased heart rate, weight gain, increased appetite, muscle twitching, uncontrolled movements of the limbs, and feeling dizzy, especially when getting up from a lying or sitting position, were common (greater than 1 in 100 patients).
Croatian: Adolescenti u dobi od 13 ili više godina imali su nuspojave slične učestalosti i vrste kao i odrasli bolesnici, osim što su pospanost, nekontrolirano trzanje mišića ili trzajni pokreti, nemir i umor bili vrlo česti (javljali su se u više od 1 na 10 bolesnika), dok su bol u gornjem dijelu trbuha, suha usta, ubrzani otkucaji srca, povećanje tjelesne težine, pojačan apetit, trzanje mišića, nekontrolirani pokreti udova i osjećaj omaglice, osobito pri ustajanju iz ležećeg ili sjedećeg položaja, bili česti (javljali su se u više od 1 na 100 bolesnika).
English: The most commonly reported adverse reactions in placebo-controlled trials were nausea, dizziness and somnolence each occurring in more than 3 % of patients treated with aripiprazole solution for injection.
Croatian: Najčešće prijavljene nuspojave u placebom kontroliranim ispitivanjima bile su mučnina, omaglica i somnolencija i svaka javlja u više od 3 % bolesnika liječenih aripiprazol otopinom za injekciju.
English: If you are receiving ABILIFY, your doctor will discuss with you whether you should breast-feed considering the benefit to you of your therapy and the benefit to your baby of breast-feeding.
Croatian: Ako primate ABILIFY, Vaš će liječnik razgovarati s Vama o tome trebate li dojiti uzimajući u obzir korist liječenja za Vas i korist dojenja za dijete.
English: • excessive sweating,
Croatian: • pojačano znojenje;
English: Dizziness and vision problems may occur during treatment with this medicine (see section 4).
Croatian: Tijekom liječenja ovim lijekom mogu se javiti omaglica i problemi s vidom (pogledajte dio 4.).
English: Intramuscular use.
Croatian: Za intramuskularnu primjenu.
English: ABILIFY solution for injection is indicated for the rapid control of agitation and disturbed behaviours in adult patients with schizophrenia or with manic episodes in Bipolar I Disorder, when oral therapy is not appropriate.
Croatian: ABILIFY otopina za injekciju indicirana je za brzo postizanje kontrole agitacije i poremećenog ponašanja u odraslih bolesnika sa shizofrenijom ili maničnim epizodama u bipolarnom poremećaju tipa I, kad se ne može primijeniti oralna terapija.
English: Red iron oxide (E 172)
Croatian: crveni željezov oksid (E 172)
English: In intravenous reproductive toxicity studies, no new safety concerns were observed at maternal exposures up to 15 (rat) and 29 (rabbit) times human exposure at 30 mg.
Croatian: U ispitivanjima intravenske reproduktivne toksičnosti, nisu bili primijećeni novi upozoravajući znakovi u vezi sa sigurnošću aripiprazol otopine za injekciju pri izloženosti majke koja je bila do 15 (štakor) i 29 (kunić) puta veća od izloženosti u ljudi nakon doze od 30 mg.
English: • tricyclic's (such as clomipramine and amitriptyline) used for depressive illness
Croatian: • triciklički antidepresivi (kao što su klomipramin i amitriptilin) koji se primjenjuju kod depresivne bolesti
English: Since patients treated with antipsychotics often present with acquired risk factors for VTE, all possible risk factors for VTE should be identified before and during treatment with aripiprazole and preventive measures undertaken (see section 4.8).
Croatian: Budući da bolesnici liječeni antipsihoticima često već imaju stečene čimbenike rizika za VTE, prije i tijekom liječenja aripiprazolom moraju se utvrditi svi mogući čimbenici rizika za VTE i poduzeti preventivne mjere (vidjeti dio 4.8).
English: Aripiprazole is well absorbed when administered orally as the solution.
Croatian: Aripiprazol se dobro apsorbira kada se primjenjuje u obliku oralne otopine.
English: Based on results from trials with oral administration of aripiprazole, aripiprazole is widely distributed throughout the body with an apparent volume of distribution of 4.9 L/kg, indicating extensive extravascular distribution.
Croatian: Prema rezultatima iz ispitivanja oralno primijenjenog aripiprazola, aripiprazol se opsežno raspodjeljuje po cijelom tijelu uz prividan volumen raspodjele od 4,9 l/kg, koji ukazuje na opsežnu ekstravaskularnu raspodjelu.
English: Patients were 7 to 17 years of age and presented an average score of 30 on Total Tic Score on the Yale Global Tic Severity Scale (TTS-YGTSS) at baseline.
Croatian: Bolesnici su bili u dobi od 7 do 17 godina i imali su prosječno 30 bodova na početku ispitivanja za ukupni zbroj tikova na Yaleovoj općoj ljestvici težine tikova (engl.
English: An additional finding was cholelithiasis as a consequence of precipitation of sulphate conjugates of hydroxy metabolites of aripiprazole in the bile of monkeys after repeated oral dosing at 25 mg/kg/day to 125 mg/kg/day (1 to 3 times the mean steady-state AUC at the maximum recommended clinical dose or 16 to 81 times the maximum recommended human dose based on mg/m2).
Croatian: Dodatni nalaz bio je kolelitijaza kao posljedica precipitacije sulfatnih konjugata hidroksi metabolita aripiprazola u žuči majmuna nakon ponovljenih peroralnih doza od 25 mg/kg/dan do 125 mg/kg/dan (1 do 3 puta veća od srednje vrijednosti AUC-a u stanju dinamičke ravnoteže pri maksimalnoj preporučenoj kliničkoj dozi ili 16 do 81 puta veća od maksimalne preporučene doze za ljude temeljene na mg/m2).
English: Yellow iron oxide (E 172)
Croatian: žuti željezov oksid (E 172)
English: The oral solution contains fructose and sucrose.
Croatian: Oralna otopina sadrži fruktozu i saharozu.
English: • other anti-depressants (such as venlafaxine and tryptophan) used in major depression
Croatian: • drugi antidepresivi (kao što su venlafaksin i triptofan) koji se primjenjuju kod velike depresije
English: ABILIFY contains aspartame
Croatian: ABILIFY sadrži aspartam
English: These included: dose-dependent adrenocortical toxicity (lipofuscin pigment accumulation and/or parenchymal cell loss) in rats after 104 weeks at 20 mg/kg/day to 60 mg/kg/day (3 to 10 times the mean steady-state AUC at the maximum recommended human dose) and increased adrenocortical carcinomas and combined adrenocortical adenomas/carcinomas in female rats at 60 mg/kg/day (10 times the mean steady-state AUC at the maximum recommended human dose).
Croatian: Oni su uključivali adrenokortikalnu toksičnost ovisnu o dozi (akumulacija pigmenta lipofuscina i/ili gubitak stanica parenhima) u štakora nakon 104 tjedna primjene doze od 20 mg/kg/dan do 60 mg/kg/dan (3 do 10 puta veća od srednje vrijednosti AUC-a u stanju dinamičke ravnoteže pri maksimalnoj preporučenoj dozi za ljude) i povišenu učestalost adrenokortikalnih karcinoma te kombinaciju adrenokortikalnih adenoma/karcinoma u ženki štakora koje su primale dozu od 60 mg/kg/dan (10 puta veća od srednje vrijednosti AUC-a u stanju dinamičke ravnoteže pri maksimalnoj preporučenoj dozi za ljude).
English: The ABILIFY solution for injection is a clear, colourless, aqueous solution.
Croatian: ABILIFY otopina za injekciju je bistra, bezbojna, vodena otopina.
English: • high blood pressure,
Croatian: • visoki krvni tlak, • nesvjestica,
English: • antifungal medicines (such as ketoconazole, itraconazole)
Croatian: • lijekove za liječenje gljivičnih infekcija (kao što su ketokonazol, itrakonazol)
English: Patients can experience increased urges, particularly for gambling, and the inability to control these urges while taking aripiprazole.
Croatian: Patološko kockanje i drugi poremećaji kontrole nagona Bolesnici mogu osjetiti pojačane porive, osobito za kockanjem, te nemogućnost kontroliranja tih poriva dok uzimaju aripiprazol.
English: • hearing, seeing or sensing things which are not there, suspiciousness, mistaken beliefs,
Croatian: • situacije u kojima bolesnik čuje, vidi ili osjeća stvari kojih nema, sumnjičavost, pogrešno vjerovanje, nepovezan govor i ponašanje te emocionalna tupost.
English: If you take more ABILIFY than you should
Croatian: Ako uzmete više lijeka ABILIFY nego što ste trebali
English: The most commonly reported adverse reactions in placebo-controlled trials were akathisia and nausea each occurring in more than 3 % of patients treated with oral aripiprazole.
Croatian: Najčešće prijavljene nuspojave u placebom kontroliranim ispitivanjima bile su akatizija i mučnina, od kojih se svaka javlja u više od 3 % bolesnika liječenih oralnim aripiprazolom.
English: • combination of fever, muscle stiffness, faster breathing, sweating, reduced consciousness and sudden changes in blood pressure and heart rate, fainting (neuroleptic malignant syndrome),
Croatian: • kombinacija vrućice, ukočenosti mišića, ubrzanog disanja, znojenja, smanjene svijesti i iznenadnih promjena krvnog tlaka i brzine otkucaja srca, nesvjestica (neuroleptički maligni sindrom)
English: A vial contains 9.75 mg (1.3 mL) aripiprazole.
Croatian: Bočica sadrži 9,75 mg (1,3 ml) aripiprazola.
English: A. MANUFACTURERS RESPONSIBLE FOR BATCH RELEASE
Croatian: PRILOG II A. PROIZVOĐAČI ODGOVORNI ZA PUŠTANJE SERIJE LIJEKA U PROMET
English: Aripiprazole was superior to placebo in change from baseline at week 4 and at week 12 on the Y-MRS total score.
Croatian: Aripiprazol je bio superioran u odnosu na placebo kada je u pitanju promjena ukupnog YMRS rezultata u 4. i 12. tjednu u odnosu na početnu vrijednost.
English: • nervousness,
Croatian: • nervoza,
English: Four mood stabilizer subgroups were assessed in the randomised phase: aripiprazole + lithium; aripiprazole + valproate; placebo + lithium; placebo + valproate.
Croatian: Četiri podskupine stabilizatora raspoloženja su se procjenjivale u randomiziranoj fazi: aripiprazol + litij, aripiprazol
English: In a haloperidol-controlled trial, the proportion of responder patients maintaining response to medicinal product at 52-weeks was similar in both groups (oral aripiprazole 77 % and haloperidol 73 %).
Croatian: U haloperidolom kontroliranom ispitivanju, udio bolesnika u kojih se održao terapijski odgovor na lijek do 52. tjedna ispitivanja bio je sličan u obje skupine (oralni aripiprazol 77 % i haloperidol 73 %).
English: Each carton contains one bottle and both a calibrated polypropylene measuring cup and a calibrated polypropylene low-density polyethylene dropping pipette.
Croatian: Jedna kutija sadrži jednu bocu te kalibriranu polipropilensku odmjernu čašicu i kalibriranu kapaljku od polipropilena i polietilena male gustoće.
English: • swelling of hands, ankles or feet,
Croatian: • bol u prsištu, • oticanje šaka, gležnjeva ili stopala,
English: Similarly, for dehydro-aripiprazole the geometric means of Cmax and AUC after carbamazepine co-administration were 69 % and 71 % lower, respectively, than those following treatment with aripiprazole alone.
Croatian: Slično tome, geometrijski određena srednja vrijednost Cmax dehidro-aripiprazola nakon zajedničke primjene s karbamazepinom bila je manja za 69 %, a AUC-a za 71 % od onih nakon liječenja samo aripiprazolom.
English: If signs and symptoms of tardive dyskinesia appear in a patient on aripiprazole, dose reduction or discontinuation should be considered (see section 4.8).
Croatian: Ako se u bolesnika koji uzima aripiprazol pojave znakovi i simptomi tardivne diskinezije, mora se razmotriti smanjenje doze ili prekid terapije (vidjeti dio 4.8).
English: If you forget to take ABILIFY
Croatian: Ako ste zaboravili uzeti ABILIFY
English: - binge eating (eating large amounts of food in a short time period) or compulsive eating
Croatian: - prejedanje (jedenje ogromnih količina hrane u kratkom razdoblju) ili kompulzivno jedenje (jedenje veće količine hrane nego što je normalno i više nego je potrebno za utaženje gladi), - sklonost da se odluta.
English: • anticonvulsants used to treat epilepsy (such as carbamazepine, phenytoin, phenobarbital)
Croatian: • antikonvulzive koji se primjenjuju za liječenje epilepsije (kao što su karbamazepin, fenitoin,
English: • The other ingredients are disodium edetate, fructose, glycerin, lactic acid, methyl parahydroxybenzoate (E218), propylene glycol, propyl parahydroxybenzoate (E216), sodium hydroxide, sucrose, purified water, and orange flavour.
Croatian: • Drugi sastojci su dinatrijev edetat, fruktoza, glicerin, laktatna kiselina, metilparahidroksibenzoat (E 218), propilenglikol, propilparahidroksibenzoat (E 216), natrijev hidroksid, saharoza,
English: ABILIFY solution for injection is for intramuscular use.
Croatian: ABILIFY otopina za injekciju namijenjena je za intramuskularnu primjenu.
English: ABILIFY is effective in a dose range of 10 mg/day to 30 mg/day (i.e. 10 mL to 30 mL solution/day).
Croatian: ABILIFY je učinkovit u rasponu doza od 10 mg/dan do 30 mg/dan (tj. 10 ml do 30 ml otopine/dan).
English: In a relative bioavailability study comparing the pharmacokinetics of 30 mg aripiprazole as the oral solution to 30 mg aripiprazole tablets in healthy subjects, the solution to the tablet ratio of geometric mean Cmax values was 122 % (n = 30).
Croatian: U ispitivanju relativne bioraspoloživosti, u kojem se farmakokinetika 30 mg aripiprazola primijenjena u obliku oralne otopine uspoređivala s onom kada je aripiprazol promijenjen u dozi od 30 mg u obliku tableta u zdravih ispitanika, omjer geometrijskih srednjih vrijednosti Cmax između otopine i tableta iznosio je 122 % (n = 30).
English: ABILIFY is for oral use.
Croatian: ABILIFY je namijenjen za peroralnu primjenu.
English: In the pooled trials, the incidence of low serum prolactin levels in females (< 3 ng/mL) and males (< 2 ng/mL) in aripiprazole-treated patients was 27/46 (58.7 %) and 258/298 (86.6 %), respectively.
Croatian: U objedinjenim je ispitivanjima incidencija niske razine prolaktina u serumu u djevojčica (< 3 ng/ml) liječenih aripiprazolom iznosila 27/46 (58,7 %), a u dječaka (< 2 ng/ml) 258/298 (86,6 %).
English: • uncontrollable twitching, jerking or writhing movements, restless legs,
Croatian: • nekontrolirano trzanje mišića, trzajni ili savijajući pokreti, nemirne noge,
English: In three placebo-controlled trials (n = 938; mean age: 82.4 years; range: 56 to 99 years) of aripiprazole in elderly patients with psychosis associated with Alzheimer's disease, patients treated with aripiprazole were at increased risk of death compared to placebo.
Croatian: 82,4 godine; raspon: 56 do 99 godina) s psihozom koja je bila povezana s Alzheimerovom bolešću, bolesnici liječeni aripiprazolom imali su povišen rizik od smrti u odnosu na bolesnike koji su primali placebo.
English: Aripiprazole has minor to moderate influence on the ability to drive and use machines due to potential nervous system and visual effects, such as sedation, somnolence, syncope, vision blurred, diplopia (see section 4.8).
Croatian: Aripiprazol malo do umjereno utječe na sposobnost upravljanja vozilima i rada sa strojevima zbog mogućih učinaka na živčani i vidni sustav, kao što su sedacija, somnolencija, sinkopa, zamagljen vid,
English: • skin rash,
Croatian: • kožni osip,
English: Irritability associated with autistic disorder in paediatric patients (see section 4.2) Aripiprazole was studied in patients aged 6 to 17 years in two 8-week, placebo-controlled trials [one flexible-dose (2 mg/day to 15 mg/day) and one fixed-dose (5 mg/day, 10 mg/day, or 15 mg/day)] and in one 52-week open-label trial.
Croatian: Aripiprazol se ispitivao u bolesnika u dobi od 6 do 17 godina u dva placebom kontrolirana ispitivanja u trajanju od 8 tjedana [jedno s fleksibilnom dozom (2 mg/dan do 15 mg/dan), drugo s fiksnom dozom (5 mg/dan, 10 mg/dan ili 15 mg/dan)] i jednom otvorenom ispitivanju u trajanju od 52 tjedna.
English: In clinical studies, 10 mg/day to 30 mg/day doses of aripiprazole had no significant effect on the metabolism of substrates of CYP2D6 (dextromethorphan/3-methoxymorphinan ratio), CYP2C9 (warfarin), CYP2C19 (omeprazole), and CYP3A4 (dextromethorphan).
Croatian: U kliničkim ispitivanjima, doze aripiprazola od 10 mg/dan do 30 mg/dan nisu imale značajnog učinka na metabolizam supstrata CYP2D6 (omjer dekstrometorfan/3-metoksimorfinan), CYP2C9 (varfarin), CYP2C19 (omeprazol) ni CYP3A4 (dekstrometorfan).
English: Population pharmacokinetic evaluation showed no evidence of race-related differences on the pharmacokinetics of aripiprazole.
Croatian: Rasa Populacijska farmakokinetička procjena nije dala nikakve dokaze da postoje razlike povezane s rasom u farmakokinetici aripiprazola.