FrancophonIA/ELRC3.0 huggingface dataset:
English: The safety and efficacy of INOmax in premature infants less than 34 weeks of gestation has not yet been established.
Croatian: Pedijatrijska populacija Sigurnost i djelotvornost INOmax-a u nedonoščadi gestacijske dobi manje od 34 tjedana još nije ustanovljena.
English: The NO2 concentration should be maintained as low as possible and always < 0.5 ppm.
Croatian: mora biti što niža, a uvijek mora biti < 0,5 ppm.
English: Method of administration For endotracheopulmonary use.
Croatian: Za endotraheopulmonalnu primjenu.
English: Transport of gas cylinders
Croatian: Prijevoz spremnika s plinom
English: All equipment, including connectors, tubing, and circuits, used in the delivery of nitric oxide must be made of materials compatible with the gas.
Croatian: Sva oprema, uključujući priključke, cijevi i krugove, koja se koristi za dopremu dušikovog (II) oksida mora biti proizvedena od materijala kompatibilnih s tim plinom.
English: When connecting an INOmax cylinder to the delivery system, always secure that the cylinder concentration is of the same concentration for which the system is configured.
Croatian: Prilikom priključivanja spremnika s INOmax-om na sustav za dopremu uvijek osigurajte da koncentracija u spremniku odgovara koncentraciji na koju je konfiguriran sustav.
English: If the NO2 is > 0.5 ppm, the delivery system should be assessed for malfunction, the NO2 analyser should be recalibrated, and the INOmax and/or FiO2 should be reduced if possible.
Croatian: Ako je koncentracija NO2 > 0,5 ppm, mora se provjeriti radi li sustav za dopremu plina ispravno, potrebno je ponovno kalibrirati analizator NO2, a vrijednosti INOmax i/ili FiO2 moraju se, po mogućnosti, smanjiti.
English: The inspired INOmax concentration must be measured continuously in the inspiratory limb of the circuit near the patient.
Croatian: Koncentracija udahnutog INOmax-a mora se mjeriti kontinuirano u inspiratornom kraku sustava u blizini bolesnika.
English: INOmax is available in 2 litre and 10 litre aluminium gas cylinder.
Croatian: INOmax je dostupan u aluminijskim spremnicima za plin od 2 litre i 10 litara.
English: Available data suggest additive effects on central circulation, pulmonary artery pressure and right ventricular performance.
Croatian: Dostupni podaci sugeriraju aditivne učinke na središnju cirkulaciju, plućni arterijski tlak i funkciju desne srčane klijetke.
English: The lowest effective dose will be sought.
Croatian: Liječnik će pokušati utvrditi i primijeniti najnižu učinkovitu dozu.
English: Methaemoglobin concentrations increase during the first 8 hours of nitric oxide exposure.
Croatian: Koncentracije methemoglobina povećavaju se tijekom prvih 8 sati izlaganja dušikovom (II) oksidu.
English: Attempts to wean INOmax should be commenced as soon as the haemodynamics have stabilised in conjunction to weaning from ventilator and inotropic support.
Croatian: Pokušaj odvikavanja od INOmax-a potrebno je započeti odmah nakon stabilizacije hemodinamike u kombinaciji s odvikavanjem od ventilacijske i inotropne potpore.
English: For patient safety, appropriate alarms must be set for INOmax (± 2 ppm of the prescribed dose), NO2 (1 ppm), and FiO2 (± 0.05).
Croatian: Radi sigurnosti bolesnika preporučuje se postavljanje odgovarajućih alarma za INOmax (± 2 ppm propisane doze), NO2 (1 ppm) i FiO2 (± 0,05).
English: In neonates with PPHN, INOmax can improve oxygenation (as indicated by significant increases in PaO2).
Croatian: U novorođenčadi s PPHN, INOmax može poboljšati oksigenaciju (što pokazuje značajno povećanje PaO2).
English: At the request of the European Medicines Agency;
Croatian: Ažurirani RMP treba dostaviti: • na zahtjev Europske agencije za lijekove;
English: Linde Gas Therapeutics Benelux B.V. De Keten 7
Croatian: Linde Gas Therapeutics Benelux B.V.
English: Methaemoglobin level should be measured within one hour after initiation of INOmax therapy, using an analyser which can reliably distinguish between foetal haemoglobin and methaemoglobin.
Croatian: Potrebno je izmjeriti razinu methemoglobina unutar jednog sata nakon početka terapije INOmax-om analizatorom koji može pouzdano razlikovati fetalni hemoglobin i methemoglobin.
English: D. CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND
Croatian: UVJETI ILI OGRANIČENJA VEZANI UZ SIGURNU I
English: Tests show that dry nitric oxide mixtures can be used with most materials.
Croatian: Ispitivanja pokazuju da se mješavine suhog dušikovog (II) oksida mogu koristiti s većinom materijala.
English: If at any time the NO2 concentration exceeds 1 ppm, the nitric oxide dose should immediately be reduced.
Croatian: Ako koncentracija NO2 u bilo kojem trenutku prekorači 1 ppm, doza dušikovog (II) oksida odmah se mora smanjiti.
English: If there is no change in oxygenation during administration of INOmax at 1 ppm, the FiO2 should be increased by 10 %, the INOmax is discontinued, and the neonates monitored closely for signs of hypoxaemia.
Croatian: Ako nema promjene u oksigenaciji tijekom primjene INOmax-a u dozi od 1 ppm, FiO2 treba povećati za 10%, prekinuti davanje INOmax-a te pažljivo pratiti znakove hipoksemije u novorođenčeta.
English: Data further suggested a lack of additional benefit for the higher dose of nitric oxide.
Croatian: Podaci su nadalje sugerirali nedostatak dodatnih prednosti više doze dušikovog (II) oksida.
English: There are also animal data suggesting an increased susceptibility to airway infections upon exposure to low levels of NO2.
Croatian: Podaci dobiveni ispitivanjem na životinjama sugeriraju povećanu sklonost infekcijama dišnih puteva nakon izlaganja niskim razinama NO2.
English: The INOT25 trial, studying the effects of iNO in hypoxic preterm neonates, did not show improvement in alive without BPD.
Croatian: Ispitivanje INOT25, koje se bavilo učincima iNO u hipoksičnoj nedonoščadi nije pokazala poboljšanja u preživjeloj populaciji bez BPD-a.
English: INOmax should only be delivered according to a neonatologist's prescription.
Croatian: INOmax se smije primijeniti samo kako je propisao neonatolog.
English: Formation of NO2
Croatian: Koncentracija NO2
English: Protect the gas cylinders from shocks, falls, oxidising and flammable materials, moisture, sources of heat or ignition.
Croatian: Spremnike s plinom zaštititi od udaraca, padova, oksidacije i zapaljivih materijala, vlage, izvora topline i zapaljenja.
English: Low blood pressure or a rebound increase in pressure in the lungs has been known to occur if treatment with INOmax is stopped suddenly without first lowering the dose.
Croatian: Poznato je da može doći do pada krvnog tlaka ili ponovnog povećanja tlaka u plućima ako se liječenje INOmax-om prekine naglo, bez postupnog smanjenja doze.
English: This may increase the right ventricular ejection fraction.
Croatian: To može povećati ejekcijsku frakciju desne klijetke.
English: Polytrifluorochloroethylene, hexafluoropropene-vinyliden copolymer and polytetraflourethylene have been used extensively with pure nitric oxide and other corrosive gases.
Croatian: Politrifluorokloroetilen, heksafluoropropen-viniliden kopolimer i politetraflouretilen široko su korišteni s čistim dušikovim (II) oksidom i drugim korozivnim plinovima.
English: Nitrate is cleared from the plasma by the kidney at rates approaching the rate of glomerular filtration.
Croatian: Nitrat se eliminira iz plazme putem bubrega brzinom sličnoj brzini glomerularne filtracije.
English: EFFECTIVE USE OF THE MEDICINAL PRODUCT
Croatian: UČINKOVITU PRIMJENU LIJEKA
English: If you stop using INOmax
Croatian: Ako prestanete primjenjivati INOmax
English: Accidental exposure to INOmax in hospital staff has been associated with adverse events (see section 4.8).
Croatian: Slučajno izlaganje bolničkog osoblja INOmax-u povezano je s nuspojavama (vidjeti dio 4.8).
English: INOmax should not be used during pregnancy or breastfeeding.
Croatian: INOmax se ne bi trebao primjenjivati tijekom trudnoće ili dojenja.
English: In adults undergoing heart surgery, methaemoglobin level should be measured within one hour of the initiation of INOmax therapy.
Croatian: U odraslih bolesnika koji se podvrgavaju operaciji srca potrebno je izmjeriti razinu methemoglobina u roku od jednog sata nakon početka terapije INOmax-om.
English: What INOmax is and what it is used for
Croatian: Što je INOmax i za što se koristi
English: The other ingredient is nitrogen.
Croatian: Drugi sastojak je dušik.
English: Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Croatian: Lijek se izdaje na ograničeni recept (vidjeti Prilog I.: Sažetak opisa svojstava, dio 4.2).
English: These effects in turn lead to improved blood circulation and oxygenation in the pulmonary circulation.
Croatian: Ovi učinci posljedično dovode do poboljšanja cirkulacije i oksigenacije u plućnoj cirkulaciji.
English: Do not use this medicine after the expiry date which is stated on the label after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na naljepnici iza oznake “Rok valjanosti”.
English: Inhaled NO has been given for time periods up to 7 days in the peri-operative setting, but common treatment times are 24 -48 hours.
Croatian: Bolesnici su inhalirali NO i do 7 dana tijekom perioperativnog razdoblja, ali liječenje je uobičajeno trajalo 24-48 sati.
English: newborn babies, babies, children, teenagers 0-17 years and adults with high blood pressure in the lungs, connected with heart surgery.
Croatian: novorođenčadi, dojenčadi, djece, adolescenata u dobi od 0 do 17 godina i odraslih s visokim krvnim tlakom u plućima povezanim s operativnim zahvatima na srcu.
English: The dose may be increased up to 40 ppm if the lower dose has not provided sufficient clinical effects.
Croatian: Doza se može povećavati do 40 ppm ako nižom dozom nisu postignuti zadovoljavajući klinički učinci.
English: Nitric oxide is genotoxic in some test systems.
Croatian: Dušikov (II) oksid genotoksičan je u nekim sustavima ispitivanja.
English: No evidence of a carcinogenic effect was apparent, at inhalation exposures up to the recommended dose (20 ppm), in rats for 20 h/day for up to two years.
Croatian: Nije bilo dokaza o kancerogenom učinku u štakora u slučaju izloženosti udisanjem do preporučene doze (20 ppm) 20 h/dan u razdoblju do dvije godine.
English: INOmax should be administered under close monitoring of haemodynamics and oxygenation.
Croatian: INOmax se mora davati uz pažljivo praćenje hemodinamike i oksigenacije.
English: No reproduction toxicity studies have been conducted.
Croatian: Nisu provedena nikakva ispitivanja toksičnosti na reprodukcijski sustav.
English: Starting as soon as possible and within 4-24 hours of therapy, the dose should be weaned to 5 ppm provided that arterial oxygenation is adequate at this lower dose.
Croatian: Što je prije moguće, odnosno u prvih 4-24 sata terapije, dozu treba postupno smanjiti na 5 ppm, uz uvjet zadržavanja adekvatne arterijske oksigenacije pri toj sniženoj dozi.
English: Effects in non-clinical studies were observed only at exposures considered sufficiently in excess of the maximum human exposure indicating little relevance to clinical use.
Croatian: 5.3 Neklinički podaci o sigurnosti primjene Učinci u nekliničkim ispitivanjima zabilježeni su samo pri izloženostima koja se smatraju znatno višim od maksimalne izloženosti za ljude, što pokazuje nisku relevantnost za kliničku upotrebu.
English: LIST OF EXCIPIENTS Also contains nitrogen.
Croatian: POPIS POMOĆNIH TVARI Također sadrži dušik.
English: Immediately prior to each patient initiation, proper procedure must be applied to purge the system of NO2.
Croatian: Neposredno prije početka terapije svakog bolesnika sustav se mora isprati od NO2.
English: No signs of any increase adverse effects were noted in this study.
Croatian: U tom ispitivanju nije zabilježeno povećanje nuspojava.
English: The mean methaemoglobin levels remained below 1 % in the placebo group and in the 5 ppm and 20 ppm INOmax groups, but reached approximately 5 % in the 80 ppm INOmax group.
Croatian: Srednje vrijednosti razine methemoglobina ostale su niže od 1% u skupini koja je dobivala placebo te u skupinama koje su dobivale doze INOmax-a od 5 ppm i 20 ppm, ali su dostigle otprilike 5% u skupini koja je dobivala INOmax u dozi od 80 ppm.
English: Treatment can be maintained up to 96 hours or until the underlying oxygen desaturation has resolved and the neonate is ready to be weaned from INOmax therapy.
Croatian: Liječenje može trajati do 96 sati ili dok se ne riješi stanje koje je uzrokovalo desaturaciju kisikom te dok novorođenče ne bude spremno na odvikavanje od liječenja INOmax-om.
English: Nitric oxide is a compound produced by many cells of the body.
Croatian: Dušikov (II) oksid je spoj koji se stvara u mnogim stanicama u tijelu.
English: Tested polymers which can be used in nitric oxide administration systems include polyethylene (PE) and polypropylene (PP).
Croatian: Ispitani polimeri koji se mogu koristiti u sustavima za primjenu dušikovog (II) oksida obuhvaćaju polietilen (PE) i polipropilen (PP).
English: When the decision is made to discontinue inhaled nitric oxide therapy, the dose should be reduced to 1 ppm for 30 minutes to one hour.
Croatian: Nakon donošenja odluke o prekidu liječenja dušikovim (II) oksidom, doza se mora smanjiti na 1 ppm tijekom 30 minuta do jedan sat.
English: INOmax should be used and administered only by personnel specially trained in the use and handling of INOmax.
Croatian: INOmax smije primjenjivati i davati samo osoblje posebno osposobljeno za korištenje INOmaxa i rukovanje njime.
English: Methaemoglobinaemia that does not resolve after reduction or discontinuation of therapy can be treated with intravenous vitamin C, intravenous methylene blue, or blood transfusion, based upon the clinical situation.
Croatian: Methemoglobinemija koja se ne riješi nakon smanjenja ili prekida terapije može se, ovisno o kliničkoj procjeni, liječiti intravenoznom primjenom vitamina C ili metilenskog modrila ili transfuzijama krvi.
English: Rebound reaction is the most commonly adverse reaction in association with the clinical use of INOmax.
Croatian: Povratna (rebound) reakcija najčešća je nuspojava povezana s kliničkom primjenom INOmax-a.
English: Overdose with INOmax will be manifest by elevations in methaemoglobin and NO2.
Croatian: Predoziranje INOmax-om manifestira se povećanjem methemoglobina i NO2.
English: The dose may be increased up to 20 ppm if the lower dose has not provided sufficient clinical effects.
Croatian: Doza se može povećavati do 20 ppm ako nižom dozom nisu postignuti zadovoljavajući klinički učinci.
English: as part of the treatment of peri- and post-operative pulmonary hypertension in adults and newborn infants, infants and toddlers, children and adolescents, ages 0-17 years in conjunction to heart surgery, in order to selectively decrease pulmonary arterial pressure and improve right ventricular function and oxygenation.
Croatian: kao dio liječenja perioperativne i postoperativne plućne hipertenzije povezane s operacijom srca u odraslih i novorođenčadi, dojenčadi i male djece, djece i adolescenata u dobi od 0 do 17 godina, radi selektivnog smanjenja plućnog arterijskog tlaka i poboljšanja funkcije desnog ventrikula te oksigenacije.
English: When the gas cylinder is empty, do not discard.
Croatian: Kada se spremnik za plin isprazni, nemojte ga baciti.
English: Instruction for disposal of gas cylinder
Croatian: Upute za zbrinjavanje spremnika za plin
English: What INOmax looks like and contents of the pack Inhalation gas
Croatian: Kako izgleda INOmax i sadržaj pakiranja
English: In one clinical study (NINOS), treatment groups were similar with respect to the incidence and severity of intracranial haemorrhage, Grade IV haemorrhage, periventricular leukomalacia, cerebral infarction, seizures requiring anticonvulsant therapy, pulmonary haemorrhage, or gastrointestinal haemorrhage.
Croatian: U jednom kliničkom ispitivanju (NINOS), ispitivane grupe bolesnika bile su slične u smislu incidencije i težine intrakranijalnog krvarenja, krvarenja IV stupnja, periventrikularne leukomalacije, cerebralnog infarkta, napadaja koji su zahtijevali antikonvulzivnu terapiju, pulmonalnog krvarenja ili gastrointestinalnog krvarenja.
English: It is unknown whether nitric oxide is excreted in human milk.
Croatian: Nije poznato izlučuje li se dušikov (II) oksid u majčino mlijeko u ljudi.
English: The BALLR1 study, also evaluating the effects of iNO in preterm neonates, but initiating iNO at 7 days and in a dose of 20 ppm, found a significant increase in neonates alive without BPD at gestational week 36, 121 (45 % vs. 95 (35.4 %) p<0.028.
Croatian: Ispitivanje BALLR1, koje se također bavilo učincima iNO u nedonoščadi, ali je iNO uveden nakon 7 dana u dozi od 20 ppm, utvrdilo je značajno povećanje u preživjele novorođenčadi bez BPD-a u 36. tjednu gestacije, 121 (45% naspram 95 (35,4%) p<0,028.
English: In newborn babies with special malformations of the heart, ‘what doctors calls congenital heart defects' inhaled nitric oxide may cause a worsening of the circulation.
Croatian: U novorođenčadi s posebnim srčanim malformacijama, koje liječnici nazivaju prirođenim srčanim manama, inhalacija dušikovog (II) oksida može uzrokovati pogoršanje cirkulacije.
English: Acute toxicity is related to anoxia resulting from elevated methaemoglobin levels.
Croatian: Akutna toksičnost odnosi se na anoksiju koja je posljedica povećanih razina methemoglobina.
English: If oxygenation falls >20 %, INOmax therapy should be resumed at 5 ppm and discontinuation of INOmax therapy should be reconsidered after 12 to 24 hours.
Croatian: Ako oksigenacija padne >20%, terapiju INOmax-om treba nastaviti u dozi od 5 ppm te ponovno razmotriti prekid terapije nakon 12 do 24 sata.
English: The effects of inhaled nitric oxide are rapid, decrease in pulmonary artery pressure and improved oxygenation is seen within 5-20 minutes.
Croatian: Do smanjenja plućnog arterijskog tlaka i poboljšane oksigenacije dolazi u roku od 5 do 20 minuta.
English: INOmax therapy must be available for manual ventilation such as suctioning, patient transport, and resuscitation.
Croatian: Terapija INOmax-om mora biti dostupna za ručnu ventilaciju u slučaju sukcije, prijevoza bolesnika i oživljavanja.
English: Treatment with inhaled nitric oxide might aggravate cardiac insufficiency in a situation with left-toright shunting.
Croatian: Liječenje inhalacijom dušikovog (II) oksida može pogoršati srčanu insuficijenciju u slučajevima lijevo-desnog shunta.
English: The lowest effective dose should be administered and the dose should be weaned down to 5 ppm provided that the pulmonary artery pressure and systemic arterial oxygenation remain adequate at this lower dose.
Croatian: Potrebno je dati najnižu učinkovitu dozu koju treba postupno smanjiti na 5 ppm, uz uvjet zadržavanja adekvatnog tlaka i sistemske arterijske oksigenacije pri toj sniženoj dozi.
English: Persistent pulmonary hypertension of the newborn (PPHN) occurs as a primary developmental defect or as a condition secondary to other diseases such as meconium aspiration syndrome (MAS), pneumonia, sepsis, hyaline membrane disease, congenital diaphragmatic hernia (CDH), and pulmonary hypoplasia.
Croatian: Perzistentna plućna hipertenzija novorođenčeta (PPHN) može biti primarna tj. uzrokovana poremećajima u razvoju ili sekundarna usljed drugih bolesti i stanja poput sindroma aspiracije mekonija, pneumonije, sepse, bolesti hijalinih membrana, kongenitalne dijafragmalne hernije i pulmonalne hipoplazije.
English: This is due to unwanted pulmonary vasodilation caused by inhaled nitric oxide, resulting in a further increase of already existing pulmonary hyperperfusion thus potentially giving raise to forward or backward failure.
Croatian: To je posljedica neželjene plućne vazodilatacije prouzročene inhalacijom dušikovog (II) oksida, što izaziva dodatno povećanje već postojeće pulmonalne hiperperfuzije te može izazvati anterogradno ili retrogradno zatajivanje srca.
English: Limay Porcheville 3 avenue Ozanne 78440 Porcheville France
Croatian: Limay Porcheville 3 avenue Ozanne 78440 Porcheville Francuska
English: In the presence of oxygen NO rapidly forms NO2, see section 4.5.
Croatian: U prisutnosti kisika NO brzo stvara NO2, vidjeti dio 4.5. 6.3 Rok valjanosti
English: If the fraction of methaemoglobin rises to a level that potentially compromises adequate oxygen delivery, the INOmax dose should be decreased and the administration of reducing medicinal products such as methylene blue may be considered.
Croatian: Ako se udio methemoglobina poveća na razinu koja može ugroziti odgovarajuću dopremu kisika, doza INOmax-a mora se smanjiti, a može se razmotriti i primjena redukcijskih sredstava poput metilenskog modrila.
English: If there is an unexpected change in INOmax concentration, the delivery system should be assessed for malfunction and the analyser should be recalibrated.
Croatian: Ako dođe do neočekivane promjene u koncentraciji INOmax-a, mora se provjeriti radi li sustav za dopremu ispravno, a analizator se mora ponovno kalibrirati.
English: The INOmax dose should not be discontinued abruptly as it may result in an increase in pulmonary artery pressure (PAP) and/or worsening of blood oxygenation (PaO2).
Croatian: Doziranje INOmax-a ne smije se naglo prekidati zbog rizika od naglog povećanja plućnog arterijskog tlaka (PAP) i/ili pogoršanje oksigenacije krvi (PaO2).
English: 4.4 Special warnings and precautions for use
Croatian: 4.4 Posebna upozorenja i mjere opreza pri uporabi Neadekvatan odgovor
English: Studies show that nitric oxide exhibits pulmonary pharmacodynamic effects at intra-airway concentrations as low as 1 ppm.
Croatian: Ispitivanja pokazuju da dušikov (II) oksid pokazuje plućne farmakodinamičke učinke i pri malim koncentracijama od 1 ppm u dišnom putu.
English: The installation of a nitric oxide pipeline system with supply station of gas cylinders, fixed network and terminal units is forbidden.
Croatian: Zabranjena je instalacija sustava cijevi za dušikov (II) oksid s dovodnom stanicom s bocama za plin, fiksnom mrežom i jedinicama s priključcima.
English: In clinical trials, no efficacy has been demonstrated with the use of inhaled nitric oxide in patients with congenital diaphragmatic hernia.
Croatian: U kliničkim ispitivanjima nije dokazana djelotvornost primjene inhalacije dušikovog (II) oksida u bolesnika s kongenitalnom dijafragmalnom hernijom.
English: Deterioration in oxygenation and elevation in PAP may also occur in neonates with no apparent response to INOmax.
Croatian: Do pogoršanja oksigenacije i povećanja PAP-a također može doći u novorođenčadi koja ne reagiraju na liječenje INOmax-om.
English: INOmax should only be delivered according to an anaesthetist's or intensive care physician's prescription.
Croatian: INOmax se smije primijeniti samo kako je propisao anesteziolog ili liječnik intenzivne skrbi.
English: No fertility studies have been performed.
Croatian: Nisu provedena ispitivanja plodnosti.
English: Storage in the pharmacy department
Croatian: Čuvanje u odjelima ljekarne
English: A. MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE
Croatian: PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE
English: 5.2 Pharmacokinetic properties
Croatian: 5.2 Farmakodinamička svojstva
English: Side effects that are very commonly seen (affects more than 1 user in 10) in association with INOmax therapy include:
Croatian: Vrlo česte nuspojave (pojavljuju se kod više od 1 na 10 korisnika) povezane s liječenjem INOmax-om su sljedeće:
English: Storage in the medical department
Croatian: Čuvanje u odjelima medicinskih ustanova
English: The delivery system must provide a constant inhaled INOmax concentration irrespective of the ventilator.
Croatian: Sustav za dopremu mora osiguravati stalnu udahnutu koncentraciju INOmax-a bez obzira na rad respiratora.
English: Nitric oxide has an unpaired electron, which makes the molecule reactive.
Croatian: Dušikov (II) oksid ima nespareni elektron koji čini molekulu aktivnom.