FrancophonIA/ELRC3.0 huggingface dataset:
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Actos have also been included in the summary of product characteristics and the package leaflet.
Croatian: U sažetku opisa svojstava lijeka i uputi o lijeku također se nalaze preporuke i mjere opreza za sigurnu i učinkovitu primjenu lijeka Glubrava kojih se zdravstveni djelatnici i bolesnici trebaju pridržavati.
English: How is Actos used?
Croatian: Kako se Actos koristi?
English: How has Actos been studied?
Croatian: Kako je Actos ispitivan?
English: The recommended dose is one tablet once a day, preferably taken with food.
Croatian: Preporučena je doza jedna tableta jedanput na dan i treba se po mogućnosti uzimati s hranom.
English: Two medicines are bioequivalent when they produce the same levels of the active substances in the body and are therefore expected to have the same effect.
Croatian: Dva su lijeka bioekvivalentna kada u tijelu proizvode jednake razine djelatnih tvari pa se stoga očekuje da imaju jednak učinak.
English: This means that it contains the same active substances and works in the same way as a ‘reference medicine' already authorised in the EU called Truvada.
Croatian: To znači da sadrži iste djelatne tvari i djeluje na isti način kao i „referentni lijek” koji je već odobren u EU-u pod nazivom Truvada.
English: In addition, it may be used in adolescents who are resistant to first-line treatments or who cannot take them because of side effects.
Croatian: Usto se može primjenjivati u adolescenata kod kojih je zabilježena rezistencija na prvu liniju liječenja ili koji ne mogu primati liječenje zbog nuspojava.
English: Both emtricitabine and tenofovir work in similar ways by blocking the activity of reverse transcriptase, an enzyme produced by HIV that allows it to reproduce itself in the cells it has infected.
Croatian: Emtricitabin i tenofovir djeluju na sličan način, onemogućujući djelovanje reverzne transkriptaze, enzima koji proizvodi virus HIV-a i koji virusu omogućuje reprodukciju u zaraženim stanicama.
English: is available as tablets (200 mg emtricitabine and 245 mg tenofovir disoproxil).
Croatian: Lijek Emtricitabine/Tenofovir disoproxil Krka d.d. dostupan je u obliku tableta (200 mg emtricitabina i 245 mg tenofovirdizoproksila).
English: does not cure HIV infection or AIDS, but it holds off the damage to the immune system and the development of infections and diseases associated with AIDS.
Croatian: Emtricitabine/Tenofovir disoproxil Krka d.d. ne liječi infekciju HIV-om ni AIDS, ali odgađa oštećenje imunosnog sustava te razvoj infekcija i bolesti povezanih s AIDS-om.
English: is an HIV medicine that is used in combination with at least one other HIV medicine to treat adults infected with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Croatian: Lijek Emtricitabine/Tenofovir disoproxil Krka d.d. lijek je protiv HIV-a koji se primjenjuje u kombinaciji s najmanje još jednim lijekom protiv HIV-a za liječenje odraslih osoba zaraženih virusom humane imunodeficijencije tipa 1 (HIV-1), virusom koji uzrokuje sindrom stečene imunodeficijencije (AIDS).
English: For more informationabout using Emtricitabine/Tenofovir disoproxil Krka d.d., see the package leaflet or contact your doctor or pharmacist.
Croatian: Više informacija o primjeni lijeka Emtricitabine/Tenofovir disoproxil Krka d.d. pročitajte u uputi o lijeku, odnosno obratite se liječniku ili ljekarniku.
English: is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine's.
Croatian: Budući da je lijek Emtricitabine/Tenofovir disoproxil Krka d.d. generički lijek te da je bioekvivalentan referentnom lijeku, smatra se da su njegove koristi i rizici isti kao i oni referentnog lijeka.
English: What measures are being taken to ensure the safe and effective use of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Emtricitabine/Tenofovir disoproxil Krka d.d.?
English: Emtricitabine/Tenofovir disoproxil Krka d.d contains two active substances, emtricitabine and tenofovir disoproxil.
Croatian: Emtricitabine/Tenofovir disoproxil Krka d.d. sadrži dvije djelatne tvari, emtricitabin i tenofovirdizoproksil.
English: The European Medicines Agency concluded that, in accordance with EU requirements, Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Europska agencija za lijekove zaključila je kako je, u skladu sa zahtjevima EU-a, utvrđeno da lijek Emtricitabine/Tenofovir disoproxil Krka d.d. posjeduje usporedivu kakvoću te da je bioekvivalentan s lijekom Truvada.
English: can be found on the Agency's website: ema.europa.eu/en/medicines/human/EPAR/emtricitabinetenofovir-disoproxil-krka-dd. Information on the reference medicine can also be found on the Agency's website.
Croatian: Više informacija o lijeku Emtricitabine/Tenofovir disoproxil Krka d.d. nalazi se na internetskim stranicama Agencije: ema.europa.eu/en/medicines/human/EPAR/emtricitabinetenofovir-disoproxilkrka-dd.
English: Emtricitabine/Tenofovir disoproxil Krka d.d., taken in combination with at least one other antiviral medicine, reduces the amount of HIV in the blood and keeps it at a low level.
Croatian: Kad se uzima u kombinaciji s najmanje još jednim protuvirusnim lijekom, Emtricitabine/Tenofovir disoproxil Krka d.d. smanjuje koncentraciju HIV-a u krvi i održava je na niskoj razini.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Preporuke i mjere opreza kojih se zdravstveni radnici i bolesnici trebaju pridržavati u cilju sigurne i učinkovite primjene lijeka Emtricitabine/Tenofovir disoproxil Krka d.d. također se nalaze u sažetku opisa svojstava lijeka i uputi o lijeku.
English: What are the benefits and risks of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Koje su koristi i rizici od lijeka Emtricitabine/Tenofovir disoproxil Krka d.d.?
English: can only be obtained with a prescription and treatment should be started by a doctor who has experience in the management of HIV infection.
Croatian: Emtricitabine/Tenofovir disoproxil Krka d.d. izdaje se samo na liječnički recept, a liječenje treba započeti liječnik s iskustvom u liječenju infekcije HIV-om.
English: contains two active substances: emtricitabine, which is a nucleoside reverse transcriptase inhibitor; and tenofovir disoproxil, which is a ‘prodrug' of tenofovir.
Croatian: Emtricitabine/Tenofovir disoproxil Krka d.d. sadrži dvije djelatne tvari: emtricitabin, nukleozidni inhibitor reverzne transkriptaze, i tenofovirdizoproksil, „prolijek” tenofovira.
English: Studies on the benefits and risks of the active substances in the authorised use have already been carried out with the reference medicine, Truvada, and do not need to be repeated for Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Ispitivanja koristi i rizika od djelatnih tvari u odobrenoj primjeni već su provedena s referentnim lijekom Truvada i stoga ih nije potrebno ponavljati za lijek Emtricitabine/Tenofovir disoproxil Krka d.d. Kao i za svaki lijek, tvrtka je dostavila podatke o ispitivanjima kakvoće za lijek Emtricitabine/Tenofovir disoproxil Krka d.d. Tvrtka je provela i ispitivanje koje je pokazalo da je lijek „bioekvivalentan” referentnom lijeku.
English: will provide an information pack to doctors which covers the potential harmful effects of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Tvrtka koja stavlja lijek Emtricitabine/Tenofovir disoproxil Krka d.d. U promet osigurat će informativni paket za liječnike koji obuhvaća potencijalne štetne učinke na funkciju bubrega prilikom primjene lijeka Emtricitabine/Tenofovir disoproxil Krka d.d. u odraslih i djece.
English: Other information about Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Ostale informacije o lijeku Emtricitabine/Tenofovir disoproxil Krka d.d.
English: As for all medicines, data on the use of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Kao i za sve lijekove, podatci o primjeni lijeka Emtricitabine/Tenofovir disoproxil Krka d.d. kontinuirano se prate.
English: Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Emtricitabine/Tenofovir disoproxil Krka d.d. (emtricitabin/tenofovirdizoproksil)
English: The European Commission granted a marketing authorisation valid throughout the EU for Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Europska komisija izdala je odobrenje za stavljanje u promet lijeka Emtricitabine/Tenofovir disoproxil Krka d.d. koje je na snazi u Europskoj uniji od 28. travnja 2017.
English: Therefore, the Agency's view was that, as for Truvada, the benefit of Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Stoga je stav Agencije da korist od lijeka Emtricitabine/Tenofovir disoproxil Krka d.d., kao i od lijeka Truvada, nadmašuje identificirani rizik te da lijek može biti odobren za primjenu u EU-u.
English: How is Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Kako se primjenjuje Emtricitabine/Tenofovir disoproxil Krka d.d.?
English: have also been included in the summary of product characteristics and the package leaflet.
Croatian: Informacije o referentnom lijeku također se nalaze na internetskim stranicama Agencije.
English: How does Emtricitabine/Tenofovir disoproxil Krka d.d.
Croatian: Kako djeluje Emtricitabine/Tenofovir disoproxil Krka d.d.?
English: All doses should be taken once daily orally (by mouth).
Croatian: Sve doze moraju se uzeti jednom dnevno (kroz usta).
English: Normalization of:f
Croatian: Normalizacija:f
English: Patients treated and monitored for resistance b
Croatian: Bolesnici liječeni i praćeni zbog rezistencije b
English: Results beyond 48 weeks of treatment
Croatian: Rezultati nakon 48 tjedana liječenja
English: the condition of your liver.
Croatian: • stanju Vaše jetre.
English: Rare (at least 1 in 10,000 patients): severe allergic reaction.
Croatian: Rijetko (u najmanje 1 na 10 000 bolesnika): teška alergijska reakcija.
English: Clinical resistance in adults
Croatian: Klinička rezistencija u odraslih
English: <Date of first authorisation: {DD month YYYY}> <Date of latest renewal: {DD month YYYY}>
Croatian: <Datum prvog odobrenja: {DD mjesec GGGG}> <Datum posljednje obnove odobrenja: {DD mjesec GGGG}>
English: The randomization was stratified by age group (2 to 6 years; >6 to 12 years; and >12 to <18 years).
Croatian: Randomizacija je stratificirana prema dobnim skupinama (2 do 6 godina; > 6 do 12 godina i > 12 do < 18 godina).
English: Infection by the hepatitis B virus can lead to damage to the liver.
Croatian: Infekcija virusom hepatitisa B može dovesti do oštećenja jetre.
English: Diameter: approximately 6.8 mm.
Croatian: Promjer: približno 6,8 mm.
English: Gender and race: no dosage adjustment based on gender or race is required.
Croatian: Spol i rasa: nije potrebna prilagodba doze na temelju spola ili rase.
English: Patients in specific year with:
Croatian: Bolesnici u određenoj godini s:
English: common: increased transaminases
Croatian: često: povišene transaminaze
English: Your child's doctor will decide the right dose based on your child's weight.
Croatian: Liječnik Vašeg djeteta odredit će odgovarajuću dozu na temelju tjelesne težine Vašeg djeteta.
English: if you are also infected with HIV (human immunodeficiency virus) be sure to tell your doctor.
Croatian: • ako ste također zaraženi HIV-om (virus humane imunodeficijencije) obavezno o tome obavijestite liječnika.
English: if you have previously received treatment for chronic hepatitis B, please inform your doctor.
Croatian: • ako ste prethodno liječeni zbog kroničnog hepatitisa B, molimo da o tome obavijestite svog liječnika.
English: Entecavir Mylan will not control your HIV infection.
Croatian: Entekavir Mylan neće kontrolirati Vašu HIV infekciju.
English: In most cases you may take Entecavir Mylan with or without food.
Croatian: U većini slučajeva možete uzimati Entekavir Mylan s hranom ili bez nje.
English: 117 Allée des Parcs 69800 Saint Priest France
Croatian: 117 Allée des Parcs 69800 Saint Priest Francuska
English: Given that the potential risks to the developing foetus are unknown, women of childbearing potential should use effective contraception.
Croatian: S obzirom na to da nisu poznati mogući rizici za razvoj fetusa, žene u reproduktivnoj dobi trebaju koristiti učinkovitu kontracepciju.
English: After adjusting for differences in creatinine clearance and body weight, elderly subjects had a 12.5% higher AUC than young subjects.
Croatian: Nakon prilagodbe za razlike u klirensu kreatinina i tjelesnoj težini, stariji ispitanici imali su 12,5% višu AUC od mladih ispitanika.
English: Patients in response were followed for an additional 24 weeks off-treatment.
Croatian: Bolesnici s odgovorom praćeni su još dodatna 24 tjedna bez liječenja.
English: Co-infection with hepatitis C or D
Croatian: Istodobna infekcija hepatitisom C ili D
English: Entecavir Mylan with food and drink
Croatian: Entekavir Mylan s hranom i pićem
English: For children and adolescents (from 2 to less than 18 years of age), your child's doctor will decide the right dose based on your child's weight.
Croatian: Za djecu i adolescente (od 2 do manje od 18 godina), liječnik Vašeg djeteta odredit će pravu dozu na temelju tjelesne težine djeteta.
English: Given the exposure margin, this finding is considered of unlikely clinical significance.
Croatian: S obzirom na granicu izloženosti, smatra se da ovaj nalaz vjerojatno nema kliničkog značaja.
English: The estimated volume of distribution for entecavir is in excess of total body water.
Croatian: Procijenjeni volumen distribucije entekavira veći je od ukupne vode u tijelu.
English: If you miss a dose of Entecavir Mylan, take it as soon as possible, and then take your next scheduled dose at its regular time.
Croatian: Ako propustite dozu lijeka Entekavir Mylan, uzmite je čim prije, a onda sljedeću dozu uzmite prema rasporedu u uobičajeno vrijeme.
English: It is important that women of childbearing age receiving treatment with Entecavir Mylan use an effective method of contraception to avoid becoming pregnant.
Croatian: Važno je da žene u reproduktivnoj dobi koje se liječe lijekom Entekavir Mylan koriste učinkovitu metodu kontracepcije, kako bi se izbjegla trudnoća.
English: Diameter: approximately 8.8 mm.
Croatian: Promjer: približno 8,8 mm.
English: *p<0.05 ULN=upper limit of normal, LLN=lower limit of normal.
Croatian: *p<0,05 GGN=gornja granica normale, DGN=donja granica normale.
English: Not all patients need to take the same dose of Entecavir Mylan.
Croatian: Ne moraju svi bolesnici uzimati istu dozu lijeka Entekavir Mylan.
English: For patients who are not able to swallow tablets, or for whom a dose reduction is recommended, other entecavir-containing products with more suitable formulations may be available.
Croatian: Za bolesnike koji ne mogu progutati tablete, ili za koje je preporučeno smanjivanje doze, mogu biti dostupni drugi lijekovi koji sadrže entekavir koji imaju prikladnije formulacije.
English: Your doctor will monitor you regularly while you are receiving Entecavir Mylan.
Croatian: Liječnik će Vas redovito pratiti dok primate Entekavir Mylan.
English: When your treatment with Entecavir Mylan is stopped, your doctor will continue to monitor you and take blood tests for several months.
Croatian: Nakon prestanka liječenja lijekom Entekavir Mylan, liječnik će Vas tijekom nekoliko mjeseci nastaviti pratiti i raditi krvne pretrage.
English: A 4-hour period of haemodialysis removed ≈ 13% of the dose, and 0.3% was removed by CAPD.
Croatian: Hemodijaliza u trajanju od 4 sata uklonila je ≈ 13% doze, a 0,3% se uklonilo pomoću KAPD.
English: After reaching peak levels, entecavir plasma concentrations decreased in a bi-exponential manner with a terminal elimination half-life of ≈ 128-149 hours.
Croatian: Nakon što je postigla vršne razine, koncentracija entekavira u plazmi smanjivala se na bieksponencijalni način s terminalnim poluvijekom eliminacije od ≈ 128-149 sati.
English: AUC was 14% higher in women than in men, due to differences in renal function and weight.
Croatian: AUC je bio 14% viši u žena nego u muškaraca, zbog razlika u funkciji bubrega i tjelesnoj težini.
English: Entecavir Mylan reduces the amount of virus in your body, and improves the condition of the liver.
Croatian: Entekavir Mylan smanjuje količinu virusa u Vašem tijelu i poboljšava stanje jetre.
English: Frequency is defined as very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000).
Croatian: Učestalost se definira kao vrlo često (≤ 1/10); često (≤ 1/100 i < 1/10); manje često (≤ 1/1000 i < 1/100); rijetko (≤ 1/10 000 i < 1/1000).
English: Lactic acidosis and severe hepatomegaly with steatosis
Croatian: Laktacidoza i teška hepatomegalija sa steatozom
English: If you were switched over to Entecavir Mylan because the treatment with lamivudine was not successful, you should take Entecavir Mylan on an empty stomach once daily.
Croatian: Ako su Vas prebacili na Entekavir Mylan zato što liječenje lamivudinom nije bilo uspješno, morate uzimati Entekavir Mylan na prazan želudac jednom dnevno.
English: Entecavir is rapidly absorbed with peak plasma concentrations occurring between 0.5-1.5 hours.
Croatian: Entekavir se brzo apsorbira s vršnim koncentracijama u plazmi između 0,5-1,5 sati.
English: Based on urinary excretion of unchanged drug, the bioavailability has been estimated to be at least 70%.
Croatian: Na temelju izlučivanja neizmijenjenog lijeka mokraćom, procijenilo se da je bioraspoloživost najmanje 70%.
English: As an alternative, in case the oral solution is not available, the dose can be adjusted by increasing the dosage interval, as detailed in the table.
Croatian: Kao druga mogućnost, u slučaju da oralna otopina nije dostupna, doza se može prilagoditi povećavanjem vremenskog razmaka između doza, kako je prikazano u tablici.
English: • decompensated liver disease (see section 4.4)
Croatian: • dekompenziranom bolešću jetre (vidjeti dio 4.4)
English: Treatment discontinuation may be considered as follows:
Croatian: Prekid liječenja mora se razmotriti u sljedećim slučajevima:
English: Children and adolescents (from 2 to less than 18 years of age) can take Entecavir Mylan with or without food.
Croatian: Djeca i adolescenti (u dobi od 2 do manje od 18 godina) mogu uzimati Entekavir Mylan s hranom ili bez nje.
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Croatian: Ako Vam je liječnik rekao da ne podnosite neke šećere, obratite se liječniku prije nego počnete uzimati ovaj lijek.
English: In HBV combination assays in cell culture, abacavir, didanosine, lamivudine, stavudine, tenofovir or zidovudine were not antagonistic to the anti-HBV activity of entecavir over a wide range of concentrations.
Croatian: U kombiniranim ispitivanjima HBV-a na kulturama stanica, abakavir, didanozin, lamivudin, stavudin, tenofovir ili zidovudin nisu imali antagonističku aktivnost na anti-HBV aktivnost entekavira u širokom rasponu koncentracija.
English: Pharmacokinetic parameters in patients with moderate or severe hepatic impairment were similar to those in patients with normal hepatic function.
Croatian: Farmakokinetički parametri u bolesnika s umjerenim ili teškim oštećenjem jetre bili su slični onima u bolesnika s normalnom funkcijom jetre.
English: Laboratory test abnormalities
Croatian: Abnormalnosti laboratorijskih nalaza
English: If your liver disease is very advanced, your doctor will also instruct you to take Entecavir Mylan on an empty stomach.
Croatian: Ako je bolest jetre jako uznapredovala, i liječnik će Vas upozoriti na to da uzimate Entekavir Mylan na prazan želudac.
English: Resistance in cell culture
Croatian: Rezistencija u staničnim kulturama
English: Year 1 Year 2 Year 3a Year 4 a Year 5a
Croatian: 1. godina 2. godina 3. godinaa 4. godinaa 5. godinaa
English: Patients treated with entecavir have reported the following side effects:
Croatian: Bolesnici koji se liječe entekavirom prijavili su sljedeće nuspojave:
English: Entecavir Mylan belongs to a class of medicines that can cause lactic acidosis (excess of lactic acid in your blood) and enlargement of the liver.
Croatian: • Entekavir Mylan pripada klasi lijekova koji mogu prouzročiti laktacidozu (suvišak mliječne kiseline u krvi) i povećanje jetre.
English: During Year 2, genotypic resistance to ETV was detected in 2 patients (1.1% cumulative probability of resistance through Year 2).
Croatian: Tijekom 2. godine, genotipska rezistencija na entekavir utvrđena je u 2 bolesnika (kumulativna vjerojatnost rezistencije do kraja 2. godine: 1,1%).
English: Histological improvementb
Croatian: Histološko poboljšanjeb
English: (Year 1), after week 58 through week 102 (Year 2), after week 102 through week 156 (Year 3), after week 156 through week 204 (Year 4), or after week 204 through week 252 (Year 5).
Croatian: 58. tjedna (1. godina), nakon 58. tjedna do 102. tjedna (2. godina), nakon 102. tjedna do 156. tjedna (3. godina), nakon 156. tjedna do 204. tjedna (4. godina) ili nakon 204. tjedna do 252. tjedna (5. godina).
English: Some patients must take Entecavir Mylan on an empty stomach (see Entecavir Mylan with food and drink in Section 2).
Croatian: Neki bolesnici moraju uzimati Entekavir Mylan na prazan želudac (pogledajte pod Entekavir Mylan s hranom i pićem u dijelu 2).
English: Patients should be advised that therapy with entecavir has not been proven to reduce the risk of transmission of HBV and therefore appropriate precautions should still be taken.
Croatian: Bolesnicima treba objasniti kako nije dokazano da terapija entekavirom smanjuje rizik od prijenosa HBV-a i da je stoga i dalje nužno primjenjivati odgovarajuće mjere opreza.
English: Study 038 included 67 HBeAg positive and 1 HBeAg negative patients co-infected with HIV.
Croatian: Ispitivanje 038 uključilo je 67 HBeAg pozitivnih i 1 HBeAg negativnog bolesnika istodobno inficiranih HIV-om.
English: Substitutions observed in clinical isolates (rtT184A, C, F, G, I, L, M or S; rtS202 C, G or I; and/or rtM250I, L or V) further decreased entecavir susceptibility 16- to 741-fold relative to wild-type virus.
Croatian: Supstitucije opažene u kliničkim izolatima (rtT184A, C, F, G, I, L, M ili S; rtS202 C, G ili I; i/ili rtM250I, L ili V) dodatno su smanjile njihovu osjetljivost na entekavir 16 do 741 puta u usporedbi s divljim tipom virusa.
English: uncommon: rash, alopecia
Croatian: manje često: osip, alopecija
English: Elderly: no dosage adjustment based on age is required.
Croatian: Starije osobe: nije potrebna prilagodba doze na temelju dobi.
English: discuss with your doctor whether your liver functions properly and, if not, what the possible effects on your Entecavir Mylan treatment may be.
Croatian: • upitajte liječnika radi li Vam jetra ispravno i, ukoliko to nije slučaj, kako bi to moglo utjecati na Vaše liječenje lijekom Entekavir Mylan.
English: A reduction of the daily dose using an oral solution is recommended.
Croatian: Preporučuje se smanjiti dnevnu dozu pomoću oralne otopine.
English: In addition, high exposures of entecavir had no relevant adverse effects on γ polymerase or mitochondrial DNA synthesis in HepG2 cells (Ki >160 µM).
Croatian: Uz to, visoke izloženosti entekaviru nisu imale štetne učinke na γ polimerazu ili sintezu mitohondrijske DNK u HepG2 stanicama (Ki > 160 µM).
English: Do not stop Entecavir Mylan without your doctor's advice Some people get very serious hepatitis symptoms when they stop taking entecavir.
Croatian: Nemojte prestati uzimati Entekavir Mylan bez savjeta liječnika Neke osobe dobiju vrlo ozbiljne simptome hepatitisa kad prestanu uzimati entekavir.
English: Dose adjustment is recommended for patients with creatinine clearance <50 ml/min, including those on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
Croatian: Preporučuje se prilagoditi dozu bolesnicima s klirensom kreatinina < 50 ml/min, uključujući bolesnike na hemodijalizi ili kontinuiranoj ambulantnoj peritonejskoj dijalizi (KAPD).