FrancophonIA/ELRC3.0 huggingface dataset:
English: In a double-blind controlled clinical trial (n=687 patients evaluated for efficacy) in non-responders to the 80 mg/12.5 mg combination, an incremental blood pressure lowering effect of the 80 mg/25 mg combination compared to continued treatment with the 80 mg/12.5 mg combination of 2.7/1.6 mmHg (SBP/DBP) was demonstrated (difference in adjusted mean changes from baseline).
Danish: I et dobbeltblindt kontrolleret klinisk studie (n=687 patienter evalueret for effekt) hos nonrespondenter i forhold til 80 mg/12,5 mg kombinationen, blev der påvist en øget blodtryktssænkende effekt ved behandling med 80 mg/25 mg kombinationen sammenlignet med fortsat behandling med 80 mg/12,5 mg kombinationen på 2,7/1,6 mmHg (SBP/DBP).
English: Abdominal pain, constipation,dyspepsia, vomiting, gastritis
Danish: Abdominalsmerter, obstipation, dyspepsi, opkastning, gastrit
English: The overall incidence of adverse reactions reported with Tolucombi was comparable to those reported with telmisartan alone in randomised controlled trials involving 1471 patients randomised to receive telmisartan plus hydrochlorothiazide (835) or telmisartan alone (636).
Danish: I randomiserede, kontrollerede forsøg med alt i alt 1471 patienter, var den totale rapporterede forekomst af bivirkninger ved brug af telmisartan/hydrochlorthiazid (835 patienter) sammenlignelig med forekomsten for telmisartan alene (636 patienter).
English: Povidone (K30) Silica, colloidal anhydrous Sodium hydroxide (E524) Sodium stearyl fumarate Sorbitol (E420) Yellow ferric oxide (E172)
Danish: Povidon (K30) Silica, kolloid vandfri Natriumhydroxid (E524) Natriumstearylfumarat Sorbitol (E420) Gul jernoxid (E172)
English: - if you have severe liver problems such as cholestasis or biliary obstruction (problems with drainage of the bile from liver and the gall bladder) or any other severe liver disease.
Danish: - hvis du har alvorlige leverproblemer, som f.eks. galdeophobning i galdegangene eller problemer med udskillelse af galde fra leveren og galdeblæren.
English: Each 80 mg/12.5 mg tablet contains 114 mg of lactose (as monohydrate) and 294.08 mg sorbitol (E420).
Danish: Hver 80 mg/12,5 mg tablet indeholder 114 mg lactose (som monohydrat) og 294,08 mg sorbitol (E420).
English: Tolucombi is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Danish: Du bør ikke tage Tolucombi tidligt i graviditeten, og du må ikke tage det, hvis du er mere end 3 måneder henne i graviditeten, da det kan give dit barn alvorlige skader.
English: Adverse reactions previously reported with one of the individual components may be potential adverse reactions with Tolucombi, even if not observed in clinical trials with this product.
Danish: Yderligere oplysninger om de enkelte komponenter Tidligere rapporterede bivirkninger for de enkelte indholdsstoffer kan også være potentielle bivirkninger i forbindelse med Tolucombi, selvom de ikke er observeret i kliniske forsøg med dette produkt.
English: This medicine contains 294.08 mg sorbitol in each tablet, which is equivalent to 5 mg/kg/day, if the body weight is 58.8 kg.
Danish: Dette lægemiddel indeholder 294,08 mg sorbitol pr. tablet, svarende til 5 mg/kg/dag, hvis kropsvægten er 58,8 kg.
English: BLISTER
Danish: Blisterkort
English: Endocrine disorders Not known: Diabetes mellitus inadequate control
Danish: Utilstrækkelig diabetes mellitus kontrol
English: Psychiatric disorders Not known: Restlessness
Danish: Psykiske forstyrrelser Ikke kendt:
English: Exposure to angiotensin II receptor antagonist therapy during the second and third trimesters is known to induce human fetotoxicity (decreased renal function, oligohydramnios, skull ossification retardation) and neonatal toxicity (renal failure, hypotension, hyperkalaemia) (See section 5.3).
Danish: Eksponering for behandling med AIIRA'er i 2. og 3. trimester vides at inducere føtotoksicitet hos mennesker (nedsat nyrefunktion, oligohydramnios, forsinket kranieossifikation) og neonatal toksicitet (nyresvigt, hypotension, hyperkaliæmi) (se også pkt.
English: Beta-blockers and diazoxide The hyperglycaemic effect of beta-blockers and diazoxide may be enhanced by thiazides.
Danish: Betablokkere og diazoxid Thiazider kan øge den hyperglykæmiske virkning af betablokkere og diazoxid.
English: Hydrochlorothiazide In patients taking hydrochlorothiazide alone the following additional side effects have been reported:
Danish: Hos patienter, der kun får hydrochlorthiazid, er der, i tillæg til de bivirkninger, som er nævnt for Tolucombi, set følgende bivirkninger:
English: Tolucombi is not indicated in patients with severe hepatic impairment.
Danish: Tolucombi må ikke gives til patienter med svært nedsat leverfunktion.
English: Angiotensin II receptor antagonists should not be initiated during pregnancy.
Danish: Behandling med AIIRA'er bør ikke initieres under graviditet.
English: Tolucombi is also available at the dose strengths 40 mg/12.5 mg and 80 mg/12.5 mg.
Danish: Tolucombi findes også i styrkerne 40 mg/12,5 mg og 80 mg/12,5 mg.
English: - Lithium containing medicines to treat some types of depression.
Danish: - Medicin, der indeholder lithium til behandling af visse typer af depression - Medicin, der kan forårsage lavt kaliumindhold i blodet (hypokaliæmi).
English: - Hyponatraemia and hypochloraemic alkalosis There is no evidence that Tolucombi would reduce or prevent diuretic-induced hyponatraemia.
Danish: Der er intet, der tyder på, at Tolucombi kan reducere eller forhindre diuretika-forårsaget hyponatriæmi.
English: Tolucombi should not be given to patients with cholestasis, biliary obstructive disorders or severe hepatic insufficiency (see section 4.3) since telmisartan is mostly eliminated with the bile.
Danish: Tolucombi bør ikke gives til patienter med kolestase, biliære obstruktive sygdomme eller svær leverinsufficiens (se pkt.
English: Blister (OPA/Al/PE foil with desiccant//Al foil): 14 x 1 tablet
Danish: Blisterkort (OPA/Al/PE folie med tørremiddel//Al folie): 14 x 1 tablet
English: Adverse reactions reported with one of the individual components may be potential adverse reactions with Tolucombi, even if not observed in clinical trials with this product.
Danish: Nedenstående bivirkninger, der er blevet rapporteret for de to aktive indholdsstoffer, er også mulige bivirkninger for Tolucombi, selvom de ikke er set i kliniske studier med dette lægemiddel.
English: Medicinal products used in the treatment for gout (e.g. probenecid, sulfinpyrazone and allopurinol) Dosage adjustment of uricosuric medicinal products may be necessary as hydrochlorothiazide may raise the level of serum uric acid.
Danish: Dosisjustering af urikosuriske midler kan være nødvendig, idet hydrochlorthiazid kan øge serumurinsyre.
English: Excipient(s) with known effect: Each tablet contains 114 mg of lactose (as monohydrate) and 294.08 mg sorbitol (E420).
Danish: Hjælpestof(fer), som behandleren skal være opmærksom på Hver tablet indeholder 114 mg lactose (som monohydrat) og 294,08 mg sorbitol (E420).
English: Tolucombi fixed dose combination (40 mg telmisartan/12.5 mg hydrochlorothiazide and 80 mg telmisartan/12.5 mg hydrochlorothiazide) is indicated in adults whose blood pressure is not adequately controlled on telmisartan alone.
Danish: Fastdosiskombinationen Tolucombi (40 mg telmisartan/12,5 mg hydrochlorthiazid og 80 mg telmisartan/12,5 mg hydrochlorthiazid) er indiceret til voksne, hvis blodtryk ikke kan reguleres tilfredsstillende med telmisartan alene.
English: - Other medicines used to treat high blood pressure, corticosteroids, painkillers (such as nonsteroidal anti-inflammatory drugs [NSAIDs]), medicines to treat cancer, gout, or arthritis.
Danish: - Blodtrykssænkende medicin, binyrebarkhormoner (kortikosteroider), smertestillende medicin såsom non-steroide antiinflamatoriske lægemider (NSAID), medicin til behandling af cancer, urinsyregigt (podagra) eller leddegigt.
English: Vascular disorders Uncommon: Hypotension, orthostatic hypotension
Danish: Hypotension, ortostatisk hypotension
English: Inflammation of the salivary gland, skin and lip cancer (Non-melanoma skin cancer), decreases in the number (or even lack) of cells in the blood, including low red and white blood cell count, serious allergic reactions (e.g. hypersensitivity, anaphylactic reaction), decreased or loss of appetite, restlessness, light-headedness, blurred or yellowing of vision, decrease in vision and eye pain (possible signs of acute myopia or acute-angle closure glaucoma), inflammation of blood vessels (vasculitis necrotising), inflamed pancreas, upset stomach, yellowing of the skin or eyes (jaundice), lupus-like syndrome (a condition mimicking a disease called systemic lupus erythematosus where the body's immune system attacks the body); skin disorders such as inflamed blood vessels in the skin, increased sensitivity to sunlight, rash, redness of the skin, blistering of the lips, eyes or mouth, skin peeling, fever (possible signs of erythema multiforme), weakness, kidney inflammation or impaired kidney function, glucose in the urine (glycosuria), fever, impaired electrolyte balance, high blood cholesterol levels, decreased blood volume, increased levels of glucose, difficulties in controlling blood/ urine levels of glucose in patients with a diagnosis of diabetes mellitus, or fat in the blood.
Danish: Betændelse i en spytkirtel, hud- og læbekræft (non-melanom hudkræft), lavt (eller endda manglende) indhold af røde og hvide blodlegemer, alvorlig allergisk reaktion (f.eks. overfølsomhed, anafylaktisk reaktion), appetitløshed, rastløshed, svimmelhed, sløret eller gulligt syn, nedsat syn og øjesmerter (mulige tegn på akut nærsynethed eller akut snævervinklet grøn stær), betændelse i blodkarrene (nekrotiserende vaskulit), betændt bugspytkirtel, maveproblemer, gul i huden eller øjnene (gulsot), lupus-lignende symptomer (bivirkninger, som ligner en sygdom kaldet systemisk lupus erythematosus, hvor kroppens immunsystem angriber kroppen), hudsygdomme som f.eks. betændte blodkar i huden, øget følsomhed for sollys, udslæt, hudrødme, blærer på læber, øjne eller mund, afskalning af hud, feber (mulige tegn på erythema multiforme), svaghed, nyrebetændelse eller nedsat nyrefunktion, sukker i urinen (glykosuri), feber, forstyrrelse i elektrolytbalancen, højt indhold af kolesterol i blodet, nedsat blodvolumen, forhøjet sukkerindhold i blodet, usikkerhed med at kontrollere sukkerindholdet i blod/urin hos patienter med diabetes mellitus eller forhøjet fedtindhold i blodet.
English: Ear and labyrinth disorders Uncommon: Vertigo
Danish: Øre og labyrint Ikke almindelig:
English: Hyperuricaemia, hyponatraemia
Danish: Hyperurikæmi, hyponatræmi
English: Inflammation of the lung (bronchitis), activation or worsening of systemic lupus erythematosus (a disease where the body's immune system attacks the body, which causes joint pain, skin rashes and fever); sore throat, inflamed sinuses; feeling sad (depression), difficulty falling asleep (insomnia), impaired vision, difficulty breathing, abdominal pain, constipation, bloating (dyspepsia), feeling sick (vomiting), inflammation of the stomach (gastritis), abnormal liver function (Japanese patients are more likely to experience this side effect), redness of the skin (erythema), allergic reactions such as itching or rash, increased sweating, hives (urticaria), joint pain (arthralgia) and pain in extremities, muscle cramps, flu-like-illness, pain, low levels of sodium, increased levels of creatinine, hepatic enzymes or creatine phosphokinase in the blood.
Danish: Lungebetændelse (bronkitis), provokation eller forværring af systemisk lupus erythematosus (en sygdom, hvor kroppens immunsystem angriber kroppen, hvilket forårsager ledsmerter, hududslæt og feber); ondt i halsen, bihulebetændelse, tristhed (depression), besvær med at falde i søvn (insomni), forringet syn, besvær med at trække vejret, mavesmerter, forstoppelse, oppustethed (dyspepsi), utilpashed (opkastning), mavekatar, unormal leverfunktion (japanske patienter har større sandsynlighed for at få denne bivirkning), rødme af huden, allergiske reaktioner såsom kløe eller udslæt, øget svedproduktion, nældefeber (urticaria), ledsmerter (arthralgi) og smerter i arme og ben, muskelkramper, influenzalignende symptomer, smerter.
English: - Tolucombi 40 mg/12.5 mg may be administered once daily in patients whose blood pressure is not adequately controlled by telmisartan 40 mg.
Danish: - Tolucombi 40 mg/12,5 mg én gang dagligt er til patienter, hvis blodtryk ikke kan reguleres tilfredsstillende med telmisartan 40 mg.
English: How to take Tolucombi
Danish: Sådan skal du tage Tolucombi
English: Tolucombi (40 mg/12.5 mg, 80 mg/12.5 mg) is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not controlled enough when telmisartan is used alone.
Danish: Tolucombi (40 mg/12,5 mg, 80 mg/12,5 mg) bruges til at sænke forhøjet blodtryk (essentiel hypertension) hos voksne, hvis blodtryk ikke er sænket tilstrækkeligt med telmisartan.
English: Decreased blood potassium levels, anxiety, fainting (syncope), sensation of tingling, pins and needles (paraesthesia), feeling of spinning (vertigo), fast heart beat (tachycardia), heart rhythm disorders, low blood pressure, a sudden fall in blood pressure when you stand up, shortness of breath (dyspnoea), diarrhoea, dry mouth, flatulence, back pain, muscle spasm, muscle pain, erectile dysfunction (inability to get or keep an erection), chest pain, increased blood uric acid levels.
Danish: Nedsat kaliumindhold i blodet, angst, besvimelse, snurrende, prikkende og stikkende fornemmelse (paræstesi), følelse af at dreje rundt (svimmelhed), hjertebanken (takykardi), forstyrret hjerterytme, lavt blodtryk, et pludseligt fald i blodtrykket når du rejser dig op, stakåndethed (dyspnø), diaré, mundtørhed, luftafgang fra tarmen, rygsmerter, muskeltrækninger, muskelsmerter, erektil dysfunktion (manglende evne til at få eller opretholde erektion), brystsmerter, forhøjet urinsyreindhold i blodet.
English: Tolucombi 80 mg/12.5 mg and Tolucombi 80 mg/25 mg contain 294.08 mg sorbitol in each tablet, which is equivalent to 5 mg/kg/day, if the body weight is 58.8 kg.
Danish: Tolucombi 80 mg/12,5 mg og Tolucombi 80 mg/25 mg indeholder 294,08 mg sorbitol pr. tablet, svarende til 5 mg/kg/dag, hvis kropsvægten er 58,8 kg.
English: Respiratory, thoracic and mediastinal disorders Uncommon: Dyspnoea Rare:
Danish: Luftveje, thorax og mediastinum Ikke almindelig:
English: Blood and lymphatic system disorders Uncommon: Anaemia Rare:
Danish: Blod og lymfesystem Ikke almindelig:
English: Tolucombi 40 mg/12.5 mg contains 147.04 mg sorbitol in each tablet, which is equivalent to 5 mg/kg/day, if the body weight is 29.8 kg.
Danish: Tolucombi 40 mg/12,5 mg indeholder 147,04 mg sorbitol pr. tablet, svarende til 5 mg/kg/dag, hvis kropsvægten er 29,8 kg.
English: Sepsis* (often called "blood poisoning"), is a severe infection with whole-body inflammatory response, rapid swelling of the skin and mucosa (angioedema); blistering and peeling of the top layer of skin (toxic epidermal necrolysis); these side effects are rare (may affect up to 1 in 1,000 people) or of unknown frequency (toxic epidermal necrolysis) but are extremely serious and patients should stop taking the medicine and see their doctor immediately.
Danish: Sepsis* (ofte kaldet "blodforgiftning", en alvorlig infektion med betændelsesreaktion i hele kroppen), hurtig hævelse af hud og slimhinder (angioødem), blærer og afskalning af det øverste lag af huden (toksisk epidermal nekrolyse).
English: Lactose monohydrate Magnesium stearate Mannitol
Danish: Hydroxypropylcellulose Lactosemonohydrat Magnesiumstearat Mannitol
English: - Tolucombi 80 mg/12.5 mg may be administered once daily in patients whose blood pressure is not adequately controlled by telmisartan 80 mg.
Danish: - Tolucombi 80 mg/12,5 mg én gang dagligt er til patienter, hvis blodtryk ikke kan reguleres tilfredsstillende med telmisartan 80 mg.
English: Musculoskeletal, connective tissue and bone disorders Not known: Weakness
Danish: Knogler, led, muskler og bindevæv Ikke kendt:
English: Amantadine Thiazides may increase the risk of adverse reactions caused by amantadine.
Danish: Amantadin Thiazider kan øge risikoen for bivirkninger ved behandling med amantadin.
English: - Medicines that may increase blood potassium levels such as potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, ACE inhibitors, cyclosporin (an immunosuppressant drug) and other medicinal products such as heparin sodium (an anticoagulant).
Danish: - Medicin, der kan forhøje indholdet af kalium i blodet, såsom vanddrivende medicin, kaliumtilskud, saltsubstitutter som indeholder kalium og ACE-hæmmere (blodtrykssænkende medicin), ciclosporin (undertrykker kroppens immunforsvar) og andre lægemidler såsom heparinnatrium (blodfortyndende medicin) .
English: - Hypercalcaemia
Danish: - Hypercalciæmi
English: An increase in cholesterol and triglyceride levels has been associated with thiazide diuretic therapy; however, at the 12.5 mg dose contained in Tolucombi, minimal or no effects were reported.
Danish: Der er dog kun rapporteret om minimal eller ingen påvirkning ved den mængde thiazid (12,5 mg), som findes i Tolucombi.
English: - Tolucombi 80 mg/25 mg may be administered once daily in patients whose blood pressure is not adequately controlled by Tolucombi 80 mg/12.5 mg or in patients who have been previously stabilised on telmisartan and hydrochlorothiazide given separately.
Danish: - Tolucombi 80 mg/25 mg én gang dagligt er til patienter, hvis blodtryk ikke kan reguleres tilfredsstillende med Tolucombi 80 mg/12,5 mg eller til patienter, som tidligere er stabiliseret med telmisartan og hydrochlorthiazid hver for sig.
English: Each tablet contains 80 mg telmisartan and 25 mg hydrochlorothiazide.
Danish: Hver tablet indeholder 80 mg telmisartan og 25 mg hydrochlorthiazid.
English: The use of Tolucombi during breast feeding is not recommended.
Danish: Det frarådes at anvende Tolucombi i ammeperioden.
English: Tolucombi 40 mg/12.5 mg tablets Each tablet contains 40 mg telmisartan and 12.5 mg hydrochlorothiazide.
Danish: Tolucombi 40 mg/12,5 mg tabletter Hver tablet indeholder 40 mg telmisartan og 12,5 mg hydrochlorthiazid.
English: (It is also better to avoid Tolucombi in early pregnancy-see pregnancy section.)
Danish: Tolucombi tidligt i graviditeten - se afsnittet ”Graviditet og amning”).
English: Psychiatric disorders Uncommon: Anxiety Rare:
Danish: Psykiske forstyrrelser Ikke almindelig:
English: Medicinal products affected by serum potassium disturbances Periodic monitoring of serum potassium and ECG is recommended when Tolucombi is administered with medicinal products affected by serum potassium disturbances (e.g. digitalis glycosides, antiarrhythmics) and the following torsades de pointes inducing medicinal products (which include some antiarrhythmics), hypokalaemia being a predisposing factor to torsades de pointes.
Danish: Lægemidler, som påvirkes af serumkaliumforstyrrelser Når Tolucombi anvendes sammen med lægemidler, hvis effekt påvirkes af serumkaliumforstyrrelser (såsom digitalisglykosider, antiarytmika) bør serumkalium og EKG monitoreres.
English: Tolucombi 80 mg/25 mg tablets
Danish: Tolucombi 80 mg/25 mg tabletter
English: Tolucombi 80 mg/12.5 mg tablets Each tablet contains 80 mg telmisartan and 12.5 mg hydrochlorothiazide.
Danish: Tolucombi 80 mg/12,5 mg tabletter Hver tablet indeholder 80 mg telmisartan og 12,5 mg hydrochlorthiazid.
English: Tél/Tel: +32 (0) 487 50 73 62
Danish: KRKA Belgium, SA. Tél/Tel: +32 (0) 487 50 73 62
English: Tolucombi fixed dose combination (80 mg telmisartan/25 mg hydrochlorothiazide) is indicated in adults whose blood pressure is not adequately controlled on Tolucombi 80 mg/12.5 mg (80 mg telmisartan/12.5 mg hydrochlorothiazide) or adults who have been previously stabilised on telmisartan and hydrochlorothiazide given separately.
Danish: Fastdosiskombinationen Tolucombi (80 mg telmisartan/25 mg hydrochlorthiazid) er indiceret til voksne, hvis blodtryk ikke kan reguleres tilfredsstillende med Tolucombi 80 mg/12,5 mg (80 mg telmisartan/12,5 mg hydrochlorthiazid) eller til patienter, som tidligere er stabiliseret med telmisartan og hydrochlorthiazid givet hver for sig.
English: Conversely, due to the antagonism of the angiotensin II (AT1) receptors by the telmisartan component of Tolucombi, hyperkalaemia might occur.
Danish: Omvendt kan hyperkaliæmi optræde på grund af telmisartans antagonistiske effekt på angiotensin II (AT1)-receptorerne.
English: Renal and urinary disorders Uncommon: Renal impairment (including acute renal failure)
Danish: Nedsat nyrefunktion (inklusive akut nyresvigt)
English: Tolucombi 40 mg/12.5 mg tablets Tolucombi 80 mg/12.5 mg tablets Tolucombi 80 mg/25 mg tablets telmisartan/hydrochlorothiazide
Danish: Tolucombi 40 mg/12,5 mg tabletter Tolucombi 80 mg/12,5 mg tabletter Tolucombi 80 mg/25 mg tabletter telmisartan/hydrochlorthiazid
English: Each 40 mg/12.5 mg tablet contains 57 mg of lactose (as monohydrate) and 147.04 mg sorbitol (E420).
Danish: Hjælpestof(fer), som behandleren skal være opmærksom på Hver 40 mg/12,5 mg tablet indeholder 57 mg lactose (som monohydrat) og 147,04 mg sorbitol (E420).
English: Tolucombi 40 mg/12.5 mg tablets Tolucombi 80 mg/12.5 mg tablets
Danish: Tolucombi 40 mg/12,5 mg tabletter Tolucombi 80 mg/12,5 mg tabletter
English: Eye disorders Not known: Xanthopsia, acute myopia, acute angle-closure glaucoma
Danish: Xantopsi, akut myopi, akut snævervinklet glaukom
English: Tolucombi 80 mg/25 mg tablets telmisartan/hydrochlorothiazide
Danish: Tolucombi 80 mg/25 mg tabletter telmisartan/hydrochlorthiazid
English: - Medicines associated with low blood potassium (hypokalaemia) such as other diuretics, ('water tablets'), laxatives (e.g. castor oil), corticosteroids (e.g. prednisone), ACTH (a hormone), amphotericin (an antifungal medicine), carbenoxolone (used to treat mouth ulcers), penicillin G sodium (an antibiotic), and salicylic acid and derivatives.
Danish: Det kan være andre vanddrivende tabletter (diuretika), afføringsmidler (f.eks. amerikansk olie), kortikosteroider (f.eks. prednison), ACTH (et hormon), amphotericin (mod svampeinfektion), carbenoxolen (til at behandle mundsår), benzylpenicillin (et antibiotikum) og salicylsyre og hermed beslægtede stoffer.
English: Each tablet contains 40 mg telmisartan and 12.5 mg hydrochlorothiazide.
Danish: Hver tablet indeholder 40 mg telmisartan og 12,5 mg hydrochlorthiazid.
English: Metabolism and nutrition disorders Uncommon: Hypokalaemia Rare:
Danish: Metabolisme og ernæring Ikke almindelig:
English: Tolucombi 80 mg/12.5 mg contains 294.08 mg sorbitol in each tablet, which is equivalent to 5 mg/kg/day, if the body weight is 58.8 kg.
Danish: Tolucombi 80 mg/12,5 mg indeholder 294,08 mg sorbitol pr. tablet, svarende til 5 mg/kg/dag, hvis kropsvægten er 58,8 kg.
English: Tolucombi is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed.
Danish: Du bør ikke tage Tolucombi, hvis du ammer, og din læge vil muligvis vælge en anden behandling til dig, hvis du ønsker at amme, især hvis dit barn er nyfødt eller født for tidligt.
English: Tolucombi (80 mg/25 mg) is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not adequately controlled by Tolucombi 80 mg/12.5 mg or in patients who have been previously stabilised by telmisartan and hydrochlorothiazide given separately.
Danish: Tolucombi (80 mg/25 mg) bruges til at sænke forhøjet blodtryk (essentiel hypertension) hos voksne, hvis blodtryk ikke er sænket tilstrækkeligt Tolucombi 80 mg/12,5 mg eller hos patienter, hvis blodtryk ikke er sænket tilstrækkeligt med enten telmisartan eller med hydrochlorthiazid.
English: Neoplasms benign, malignant and unspecified (incl cysts and polyps) Not known: Non-melanoma skin cancer (Basal cell carcinoma and Squamous cell carcinoma)
Danish: Non-melanom hudkræft (basalcellekarcinom og pladecellekarcinom)