FrancophonIA/ELRC3.0 huggingface dataset:
English: If adverse reactions such as persistent vomiting, repeated diarrhoea, blood in the stools, sudden weight loss, loss of appetite, lethargy or worsening of liver or kidney function results occur, use of the product should be discontinued and the advice of your veterinary surgeon should be sought immediately.
Slovenian: Če se pojavijo neželeni učinki, kot so trdovratno bruhanje, ponavljajoča se driska, kri v blatu, nenadna izguba telesne mase, izguba apetita, letargija ali poslabšanje delovanja ledvic ali jeter, je treba prekiniti dajanje zdravila in se takoj posvetovati z veterinarjem.
English: Mild gastro-intestinal disorders (vomiting and/or diarrhoea) were very commonly reported but these only lasted for a short time.
Slovenian: Zelo pogosto so poročali o blagih prebavnih motnjah (bruhanje in/ali driska), vendar pa trajajo kratek čas.
English: If adverse reactions such as persistent vomiting, repeated diarrhoea, faecal occult blood, sudden weight loss, anorexia, lethargy or worsening of renal or hepatic biochemistry parameters occur, use of the product should be discontinued and appropriate monitoring and/or treatment should be put in place.
Slovenian: Če se pojavijo neželeni učinki kot so trdovratno bruhanje, ponavljajoča se driska, okultna kri v blatu, nenadna izguba telesne mase, anoreksija, letargija ali poslabšanje ledvičnih ali jetrnih biokemijskih parametrov, je treba prekiniti dajanje zdravila in nato žival spremljati in/ali zdraviti.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGE Outer carton (for both blisters and bottle)
Slovenian: PODATKI NA ZUNANJI OVOJNINI Kartonska škatla (za pretisne omote in plastenke)
English: Cimicoxib is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) drug.
Slovenian: Cimikoksib je nesteroidno protivnetno zdravilo (NSAID).
English: The tablets can be divided into equal quarters.
Slovenian: Tablete se lahko razdeli na enake četrtine.
English: A. MANUFACTURING AUTHORISATION HOLDER RESPONSIBLE FOR BATCH RELEASE
Slovenian: A. IMETNIK DOVOLJENJA ZA IZDELAVO ZDRAVILA, ODGOVOREN ZA SPROSTITEV SERIJE
English: Cimicoxib may cause skin sensitisation.
Slovenian: Cimikoksib lahko povzroči kožno preobčutljivost.
English: The other metabolite, glucuronide conjugate of the demethylated cimicoxib, is eliminated in urine.
Slovenian: Drugi metabolit, glukuronid konjugat demetiliranega cimikoksiba, se izloča z urinom.
English: Blister packs - Any remaining divided tablets should be stored in the blisters but discarded if not used within 2 days.
Slovenian: Pretisni omoti - Preostale razdeljene tablete je treba shranjevati v pretisnih omotih ter jih zavreči, če se jih ne porabi v 2 dneh.
English: Bottles - Any remaining divided tablets should be stored in the bottle but discarded if not used within 90 days.
Slovenian: Plastenka - Preostale razdeljene tablete je treba shranjevati v plastenki ter jih zavreči, če se jih ne porabi v 90 dneh.
English: Any remaining divided tablets should be discarded after 90 days storage in the bottle.
Slovenian: Preostale razdeljene tablete zavrzite po 90 dneh shranjevanja v plastenkah.
English: Disposal: Read Package Leaflet.
Slovenian: Odpadki: Pred uporabo preberite navodilo za uporabo.
English: As for any long term NSAID treatment, kidney function should be monitored.
Slovenian: Kot pri vsakem dolgotrajnem zdravljenju z NSAID, je treba spremljati delovanje ledvic.
English: Other adverse reactions including loss of appetite or lethargy may also be observed on rare occasions.
Slovenian: V redkih primerih se lahko opazi tudi druge neželene učinke, vključno z izgubo apetita ali letargijo.
English: For the treatment of pain and inflammation associated with osteoarthritis, and the management of perioperative pain due to orthopaedic or soft tissue surgery, in dogs.
Slovenian: Zdravljenje bolečine in vnetja povezanega z osteoartritisom in upravljanje peri-operativne bolečine pri ortopedskih operacijah in operacijah mehkih tkiv pri psih.
English: The major metabolite, demethylated cimicoxib is mainly eliminated in faeces by the biliary route and, to a lesser extent, in urine.
Slovenian: Glavni metabolit, demetiliriani cimikoksib se večinoma izloči z žolčem preko blata in v manjšem obsegu z urinom.
English: EXPIRY DATE EXP {MM/YYYY}
Slovenian: DATUM IZTEKA ROKA UPORABNOSTI ZDRAVILA EXP {MM/YYYY}
English: Other adverse reactions including anorexia or lethargy may also be observed on rare occasions.
Slovenian: V redkih primerih se lahko opazi tudi druge neželene učinke, vključno z anoreksijo ali letargijo.
English: On rare occasions, serious gastrointestinal problems such as bleeding and ulcer formation have occurred.
Slovenian: V redkih primerih so se pojavile hude prebavne motnje, kot so krvavitev in razjede.
English: Cimalgex 8 mg cimicoxib 8 mg
Slovenian: Cimalgex 8 mg cimikoksib 8 mg
English: Any remaining divided tablets should be discarded after 2 days storage in the blisters.
Slovenian: Preostale razdeljene tablete zavrzite po 2 dneh shranjevanja v pretisnih omotih.
English: Do not use in case of hypersensitivity to cimicoxib or to any of the excipients.
Slovenian: Ne uporabite v primeru preobčutljivosti na cimikoksib ali na katero koli drugo sestavino zdravila.
English: Do not use in breeding, pregnant and lactating animals.
Slovenian: Ne uporabite pri vzrejnih živalih ter živalih v obdobju brejosti in laktacije.
English: Cimalgex 30 mg cimicoxib 30 mg
Slovenian: Cimalgex 30 mg cimikoksib 30 mg
English: MANUFACTURING AUTHORISATION HOLDER(S) RESPONSIBLE FOR BATCH RELEASE
Slovenian: IMETNIK(I) DOVOLJENJ(A) ZA IZDELAVO ZDRAVILA, ODGOVOREN(ODGOVORNI) ZA SPROŠČANJE SERIJE
English: 80 mg cimicoxib
Slovenian: 80 mg cimikoksiba
English: 30 mg cimicoxib
Slovenian: 30 mg cimikoksiba
English: Mild and transient gastro-intestinal disorders (vomiting and/or diarrhoea) were very commonly reported.
Slovenian: Zelo pogosto so poročali o blagih in prehodnih prebavnih motnjah (bruhanje in/ali driska).
English: Use this veterinary medicinal product under strict veterinary monitoring in dogs with a risk of stomach ulcers or if the animal previously displayed intolerance to other NSAIDs.
Slovenian: Pri psih s tveganjem za želodčne čire ali če je žival že predhodno pokazala netoleranco na nesteroidna protivnetna zdravila NSAID uporabite to zdravilo le pod strogim veterinarskim nadzorom.
English: Each tablet contains: Cimicoxib 8 mg Cimicoxib 30 mg Cimicoxib 80 mg
Slovenian: Vsaka tableta vsebuje: Cimikoksib 8 mg Cimikoksib 30 mg Cimikoksib 80 mg
English: Cimalgex 30 mg, tablets: oblong, white to pale brown, chewable tablets with 2 break-lines on both sides.
Slovenian: Cimalgex 30 mg, tablete: podolgovate, bele do svetlo rjave, žvečljive tablete z 2 zarezama za lomljenje na obeh straneh.
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Bottle pack
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH
English: On rare occasions, serious gastrointestinal disorders such as haemorrhage and ulcer formation have been noted.
Slovenian: V redkih primerih so bile opažene hude prebavne motnje, kot so krvavitev in razjede.
English: Cimalgex 80 mg, tablets: oblong, white to pale brown, chewable tablets with 3 break-lines on both sides.
Slovenian: Cimalgex 80 mg, tablete: podolgovate, bele do svetlo rjave, žvečljive tablete s 3 zarezami za lomljenje na obeh straneh.
English: Use this veterinary medicinal product under strict veterinary monitoring where there is a risk of gastrointestinal ulceration, or if the animal previously displayed intolerance to NSAIDs.
Slovenian: Če obstaja tveganje za gastrointestinalne razjede, ali če je žival že pokazala netoleranco na NSAID, uporabite to zdravilo le pod strogim veterinarskim nadzorom.
English: NAME OF THE MARKETING AUTHORISATION HOLDER Vétoquinol EXPIRY DATE EXP {month/year}
Slovenian: IME IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM Vétoquinol DATUM IZTEKA ROKA UPORABNOSTI ZDRAVILA EXP {mesec/leto} ŠTEVILKA SERIJE Lot {številka} BESEDILO “SAMO ZA ŽIVALI” Samo za živali.
English: THE WORDS “FOR ANIMAL TREATMENT ONLY” For animal treatment only.
Slovenian: ŠTEVILKA SERIJE Lot {številka} DATUM IZTEKA ROKA UPORABNOSTI ZDRAVILA EXP {mesec/leto} BESEDILO “SAMO ZA ŽIVALI” Samo za živali.
English: Do not use in breeding, pregnant or lactating bitches.
Slovenian: Ne uporabite pri vzrejnih psicah in pri psicah v obdobju brejosti ali laktacije.
English: Cimalgex 8 mg, tablets: oblong, white to pale brown, chewable tablets with 1 break-line on both sides.The tablets can be divided into equal halves.
Slovenian: Cimalgex 8 mg, tablete: podolgovate, bele do svetlo rjave, žvečljive tablete z 1 zarezo za lomljenje na obeh straneh.
English: STATEMENT OF ACTIVE AND OTHER SUBSTANCES 8 mg cimicoxib
Slovenian: KOLIČINA ZDRAVILNE UČINKOVINE 8 mg cimikoksiba
English: Symptomatic, supportive therapy is recommended consisting of administration of gastrointestinal protective agents and infusion of isotonic saline.
Slovenian: Priporoča se dajanje zaščitnih sredstev za prebavila in infuzija fiziološke raztopine.
English: Cimalgex 8 mg tablets for dogs Cimalgex 30 mg tablets for dogs Cimalgex 80 mg tablets for dogs cimicoxib
Slovenian: Cimalgex 8 mg žvečljive tablete za pse Cimalgex 30 mg žvečljive tablete za pse Cimalgex 80 mg žvečljive tablete za pse cimikoksib
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Cimalgex 8 mg chewable tablets for dogs Cimalgex 30 mg chewable tablets for dogs Cimalgex 80 mg chewable tablets for dogs Cimicoxib
Slovenian: IME ZDRAVILA ZA UPORABO V VETERINARSKI MEDICINI Cimalgex 8 mg žvečljive tablete za pse Cimalgex 30 mg žvečljive tablete za pse Cimalgex 80 mg žvečljive tablete za pse cimikoksib
English: NAME OF THE VETERINARY MEDICINAL PRODUCT Cimalgex 8 mg chewable tablets for dogs Cimalgex 30 mg chewable tablets for dogs Cimalgex 80 mg chewable tablets for dogs
Slovenian: IME ZDRAVILA ZA UPORABO V VETERINARSKI MEDICINI Cimalgex 8 mg žvečljive tablete za pse Cimalgex 30 mg žvečljive tablete za pse Cimalgex 80 mg žvečljive tablete za pse
English: PHARMACEUTICAL FORM Chewable tablets
Slovenian: Žvečljive tablete
English: PACKAGE LEAFLET Cimalgex 8 mg chewable tablets for dogs Cimalgex 30 mg chewable tablets for dogs Cimalgex 80 mg chewable tablets for dogs
Slovenian: NAVODILO ZA UPORABO Cimalgex 8 mg žvečljive tablete za pse Cimalgex 30 mg žvečljive tablete za pse Cimalgex 80 mg žvečljive tablete za pse
English: The review looked at data from several studies including:
Slovenian: V okviru pregleda so bili pregledani podatki iz več študij, med drugim:
English: • If you have any questions, speak with your doctor or pharmacist.
Slovenian: • Če imate dodatna vprašanja, se posvetujte z zdravnikom ali farmacevtom.
English: 22 May 2015 EMA/325007/2015
Slovenian: maj 2015 EMA/325007/2015
English: The review of ibuprofen was initiated on 9 June 2014 at the request of the UK's medicines agency (MHRA), under Article 31 of Directive 2001/83/EC.
Slovenian: Pregled ibuprofena se je začel dne 9. junija 2014 na zahtevo agencije za zdravila Združenega kraljestva (MHRA) v skladu s členom 31 Direktive 2001/83/ES.
English: The usual dose for adults and children over 12 years of age is 200 to 400 mg, 3 or 4 times a day as needed.
Slovenian: Običajni odmerek za odrasle in otroke, starejše od 12 let, je od 200 do 400 mg, 3- ali 4-krat na dan, po potrebi.
English: Dexibuprofen, the active enantiomer, is sometimes available on its own and is therefore included in this review.
Slovenian: Deksibuprofen, aktivni enantiomer, je včasih na voljo tudi samostojno, zato je bil prav tako vključen v ta pregled.
English: The review was conducted by the Pharmacovigilance Risk Assessment Committee (PRAC), the Committee responsible for the evaluation of safety issues for human medicines, which made a set of recommendations.
Slovenian: Pregled je opravil Odbor za oceno tveganja na področju farmakovigilance (PRAC), ki je odgovoren za presojo varnostnih vprašanj o zdravilih za uporabo v humani medicini, in podal več priporočil.
English: Risk factors include smoking, high blood pressure, diabetes and high blood cholesterol.
Slovenian: Dejavniki tveganja so med drugim kajenje, visok krvni tlak, sladkorna bolezen in visoke ravni holesterola v krvi.
English: 1 The CMDh is a medicines regulatory body representing the European Union (EU) Member States, Iceland, Liechtenstein and Norway.
Slovenian: 1 Skupina CMDh je regulativni organ za zdravila, ki zastopa države članice Evropske unije (EU), Islandijo, Lihtenštajn ter Norveško.
English: It works by blocking an enzyme called cyclooxygenase, which produces prostaglandins, substances that are involved in inflammation and pain.
Slovenian: Deluje tako, da zavira encim, imenovan ciklooksigenaza, ki proizvaja prostaglandine, snovi, ki sodelujejo pri vnetju in bolečinah.
English: In addition, doctors should carefully assess a patient's risk factors for heart or circulatory conditions before initiating long-term treatment with ibuprofen, particularly if high doses are required.
Slovenian: Poleg tega morajo zdravniki pri bolniku skrbno oceniti dejavnike tveganja za bolezni srca ali ožilja, preden predpišejo dolgotrajno zdravljenje z ibuprofenom, zlasti če so potrebni veliki odmerki.
English: • The effect of duration of ibuprofen treatment on cardiovascular risk is uncertain.
Slovenian: • Vpliv trajanja zdravljenja z ibuprofenom na srčno-žilno tveganje ni povsem jasen.
English: As ibuprofen medicines are all authorised nationally, the PRAC recommendations were forwarded to the Co-ordination Group for Mutual Recognition and Decentralised ProceduresHuman (CMDh), which adopted a final position.
Slovenian: Ker so vsa zdravila, ki vsebujejo ibuprofen, odobrena na nacionalni ravni, so bila priporočila odbora PRAC posredovana Usklajevalni skupini za postopek z medsebojnim priznavanjem in decentralizirani postopek - zdravila za uporabo v humani medicini (CMDh), ki je sprejela dokončno stališče.
English: Ibuprofen and dexibuprofen are currently available in the European Union (EU) in a number of different formulations.
Slovenian: Ibuprofen in deksibuprofen sta trenutno v Evropski uniji (EU) na voljo v več različnih farmacevtskih oblikah.
English: Ibuprofen is present in medicines as a mixture of two molecules that are enantiomers (mirror images of each other).
Slovenian: Ibuprofen je v zdravilih prisoten v obliki zmesi dveh molekul, ki sta enantiomera (zrcalni sliki druga druge).
English: Reviews carried out in 2005, 2006, and 2012 confirmed that NSAIDs as a class are associated with a small increase in the risk of arterial thromboembolic events (blood clots in the arteries) especially in patients with underlying heart or circulatory conditions or with certain cardiovascular risk factors, and particularly if used at high doses.
Slovenian: Pregledi, ki so jih opravili v letih 2005, 2006 in 2012, so potrdili, da je skupina nesteroidnih protivnetnih zdravil povezana z rahlo povečanim tveganjem za arterijske trombembolične dogodke (krvne strdke v arterijah), zlasti pri bolnikih z obstoječimi boleznimi srca in ožilja ali z določenimi srčno-žilnimi dejavniki tveganja, zlasti kadar se zdravila uporabljajo v velikih odmerkih.
English: Laboratory studies have shown that ibuprofen reduces the blood-thinning effects of aspirin.
Slovenian: Laboratorijske študije so pokazale, da ibuprofen zmanjša učinke aspirina na redčenje krvi.
English: A class warning of this risk is already in place and the product information for all NSAIDs, including ibuprofen, recommends that these medicines be used at the lowest effective dose and for the shortest period of time necessary to control symptoms.
Slovenian: Za to skupino je že bilo izdano opozorilo o omenjenem tveganju, informacije o zdravilu za vsa nesteroidna protivnetna zdravila, tudi za ibuprofen, pa vsebujejo priporočilo, naj se ta zdravila uporabljajo pri najmanjšem učinkovitem odmerku in najkrajši možni čas, ki je potreben za obvladanje simptomov.
English: They are available on prescription and over the counter.
Slovenian: Izdajajo se na recept in brez recepta.
English: The review covered formulations for systemic use (intended to act on the whole body, such as use by mouth or by injection); it did not cover formulations such as gels or sprays applied to the skin of the affected area.
Slovenian: V pregled so bile vključene farmacevtske oblike za sistemsko uporabo (ki naj bi delovale na celotno telo in se uporabljajo npr. skozi usta ali z injiciranjem), ne pa tudi farmacevtske oblike, kot so geli ali pršila, ki se nanesejo na kožo prizadetega predela.
English: Occasional use of ibuprofen should not affect the benefits of low-dose aspirin.
Slovenian: Občasna uporaba ibuprofena ne bi smela vplivati na koristi nizkoodmernega aspirina.
English: • Your doctor will carefully assess you before starting treatment with high-dose ibuprofen to check if you have risk factors such as high blood pressure, high blood cholesterol, diabetes, or if you smoke.
Slovenian: • Preden boste začeli zdravljenje z velikim odmerkom ibuprofena, vas bo zdravnik skrbno ocenil, da bi preveril, ali so pri vas prisotni dejavniki tveganja, kot so visok krvni tlak, visoke ravni holesterola v krvi, sladkorna bolezen ali kajenje.
English: • Experimental data suggest long-term use of ibuprofen/dexibuprofen may reduce the cardioprotective effect of low-dose acetylsalicylic acid (typically 75 mg per day).
Slovenian: • Eksperimentalni podatki kažejo, da bi dolgotrajna uporaba ibuprofena/deksibuprofena lahko zmanjšala kardioprotektivne učinke nizkoodmerne acetilsalicilne kisline (običajno v odmerku 75 mg na dan).
English: A dose of 2,400 mg per day of ibuprofen is equivalent to 1,200 mg per day of dexibuprofen.
Slovenian: Odmerek ibuprofena 2400 mg na dan je enakovreden odmerku deksibuprofena 1200 mg na dan.
English: On 20 May 2015 the CMDh adopted its position by consensus, therefore the advice recommended by the PRAC will be implemented by the Member States where the medicines are authorised, according to an agreed timetable.
Slovenian: Skupina CMDh je dne 20. maja 2015 soglasno sprejela dokončno stališče, zato bodo države članice, v katerih so zdravila odobrena, morale izvajati priporočila odbora PRAC v skladu z dogovorjenim časovnim razporedom.
English: The CMDh1 has endorsed by consensus updated advice on the use of high-dose ibuprofen.
Slovenian: Skupina CMDh1 je soglasno podprla posodobljena priporočila za uporabo velikih odmerkov ibuprofena.
English: • Patients with risk factors for cardiovascular events (e.g. hypertension, hyperlipidaemia, diabetes mellitus and smoking) should only be treated with high-dose ibuprofen after careful consideration.
Slovenian: • Bolnike z dejavniki tveganja za srčno-žilne dogodke (npr. hipertenzija, hiperlipidemija, sladkorna bolezen in kajenje) se lahko zdravi z velikimi odmerki ibuprofena šele po temeljitem razmisleku.
English: However, it remains uncertain whether longterm use of ibuprofen in clinical practice reduces the benefits of low-dose aspirin in preventing heart attacks and strokes.
Slovenian: Vendar še vedno ni jasno, ali dolgotrajna uporaba ibuprofena v klinični praksi zmanjša koristi nizkoodmernega aspirina pri preprečevanju srčnih in možganskih kapi.
English: Ibuprofen and dexibuprofen medicines have been authorised in the EU through national approval procedures and have been available for many years under a wide range of trade names.
Slovenian: Zdravila, ki vsebujejo ibuprofen in deksibuprofen, so bila v EU odobrena po nacionalnih postopkih in so že več let na voljo pod različnimi tržnimi imeni.
English: For diclofenac, the risk was estimated at about 3 extra cases of heart attack in every 1,000 patients taking diclofenac for a year.
Slovenian: Tveganje pri uporabi diklofenaka po ocenah zajema približno 3 dodatne primere srčne kapi na vsakih 1000 bolnikov, ki eno leto jemljejo diklofenak.
English: This is because ibuprofen may competitively inhibit the effect of low dose acetylsalicylic acid on platelet aggregation when they are used concomitantly.
Slovenian: Ibuprofen lahko namreč kompetitivno zavira učinek nizkoodmerne acetilsalicilne kisline na agregacijo trombocitov, kadar se zdravili uporabljata sočasno.
English: More about the safety of NSAIDs
Slovenian: Več o varnosti nesteroidnih protivnetnih zdravil
English: For diclofenac, the risk was estimated at around three additional major vascular events per 1,000 participants per year.
Slovenian: Tveganje pri uporabi diklofenaka po ocenah zajema približno tri dodatne pomembnejše vaskularne dogodke na 1000 bolnikov na leto.
English: • High doses of ibuprofen should be avoided in patients with cardiovascular conditions (e.g. uncontrolled hypertension, congestive heart failure (NYHA class II-III), established ischaemic heart disease, peripheral arterial disease and cerebrovascular disease).
Slovenian: • Uporabi velikih odmerkov ibuprofena se je treba izogibati pri bolnikih s srčno-žilnimi boleznimi (kot so npr. nenadzorovana hipertenzija, kongestivno srčno popuščanje (razreda II-III po NYHA), ugotovljena ishemična bolezen srca, periferna arterijska bolezen in možgansko-žilna bolezen).
English: • Use of high-dose ibuprofen is no longer recommended if you have heart or circulatory conditions, such as heart failure, heart disease and circulatory problems or if you have previously had a heart attack or stroke.
Slovenian: • Uporaba velikih odmerkov ibuprofena ni več priporočljiva, če imate bolezni srca ali ožilja, kot so srčno popuščanje, bolezen srca in težave z ožiljem, ali če ste že kdaj doživeli srčno ali možgansko kap.
English: The updated advice on the cardiovascular risk of high-dose ibuprofen will be included in the product information of ibuprofen medicines, along with information on the interaction between ibuprofen and aspirin.
Slovenian: Posodobljena priporočila v zvezi s srčno-žilnim tveganjem, povezanim z uporabo velikih odmerkov ibuprofena, bodo vključena v informacije o zdravilih, ki vsebujejo ibuprofen, skupaj z informacijami o medsebojnem delovanju ibuprofena in aspirina.
English: To minimise the cardiovascular risk, high doses of ibuprofen (2,400 mg per day or higher) should be avoided in patients with serious underlying heart or circulatory conditions, such as heart failure, heart disease and circulatory problems or in those who have previously had a heart attack or stroke.
Slovenian: Da bi zmanjšali srčno-žilno tveganje, se je treba uporabi velikih odmerkov ibuprofena (2400 mg na dan ali več) izogibati pri bolnikih z resnimi osnovnimi boleznimi srca ali ožilja, kot so srčno popuščanje, bolezen srca in težave z ožiljem, ter pri tistih, ki so že kdaj doživeli srčno ali možgansko kap.
English: Updated advice on use of high-dose ibuprofen
Slovenian: Posodobljena priporočila za uporabo velikih odmerkov ibuprofena
English: Ibuprofen is a painkiller and anti-inflammatory medicine that belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
Slovenian: Ibuprofen je zdravilo proti bolečinam in protivnetno zdravilo, ki spada v razred nesteroidnih protivnetnih zdravil (NSAID).
English: Review confirms small cardiovascular risk with daily doses at or above 2,400 mg
Slovenian: Pregled je potrdil majhno srčno-žilno tveganje pri uporabi dnevnih odmerkov 2400 mg ali več
English: • Prolonged use of ibuprofen may reduce the effect of low-dose aspirin when the latter is taken to reduce the risk of heart attacks and strokes.
Slovenian: • Dolgotrajnejša uporaba ibuprofena lahko zmanjša učinke nizkoodmernega aspirina, ki se jemlje za zmanjšanje tveganja za srčne in možganske kapi.
English: This latest review considered accumulated evidence which clarifies the cardiovascular risk related to ibuprofen taken at high doses and the interaction between ibuprofen at any dose and aspirin.
Slovenian: V zadnjem pregledu so proučili nakopičene dokaze, ki pojasnjujejo, kakšno je srčno-žilno tveganje, povezano z velikimi odmerki ibuprofena, in medsebojno delovanje ibuprofena v katerem koli odmerku in aspirina.