FrancophonIA/ELRC3.0 huggingface dataset:
English: Round, light beige film-coated tablet with “112” on one side.
Croatian: Okrugla, svijetlobež, filmom obložena tableta s oznakom "112" na jednoj strani.
English: Slovenská republika Merck Sharp & Dohme, s. r. o. Tel.: +421 2 58282010 dpoc_czechslovak@merck.com
Croatian: Česká republika Merck Sharp & Dohme s.r.o. Tel.: +420 233 010 111 dpoc_czechslovak@merck.com
English: Magyarország MSD Pharma Hungary Kft. Tel.: +36 1 888 5300 hungary_msd@merck.com
Croatian: Tel.: +36 1 888 5300 hungary_msd@merck.com
English: Secondary Composite Endpoint (Cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke)
Croatian: Sekundarna objedinjena mjera ishoda (smrt zbog kardiovaskularnog uzroka, infarkt miokarda bez smrtnog ishoda ili moždani udar bez smrtnog ishoda)
English: Some patients have experienced the following side effects while taking sitagliptin alone in clinical studies, or during post-approval use alone and/or with other diabetes medicines: Common: low blood sugar, headache, upper respiratory infection, stuffy or runny nose and sore throat, osteoarthritis, arm or leg pain
Croatian: Često: nizak šećer u krvi, glavobolja, infekcija gornjih dišnih puteva, začepljen nos ili curenje iz nosa i grlobolja, osteoartritis, bolovi u rukama ili nogama
English: EU/1/10/621/013 14 film-coated tablets EU/1/10/621/014 28 film-coated tablets EU/1/10/621/023 30 film-coated tablets EU/1/10/621/015 56 film-coated tablets EU/1/10/621/016 84 film-coated tablets EU/1/10/621/024 90 film-coated tablets EU/1/10/621/017 98 film-coated tablets EU/1/10/621/018 50 x 1 film-coated tablets
Croatian: EU/1/10/621/013 14 filmom obloženih tableta EU/1/10/621/014 28 filmom obloženih tableta EU/1/10/621/023 30 filmom obloženih tableta EU/1/10/621/015 56 filmom obloženih tableta EU/1/10/621/016 84 filmom obloženih tableta EU/1/10/621/024 90 filmom obloženih tableta EU/1/10/621/017 98 filmom obloženih tableta EU/1/10/621/018 50 x 1 filmom obložena tableta
English: Musculoskeletal and connective tissue disorders arthralgia
Croatian: Poremećaji mišićno-koštanog sustava i vezivnog tkiva artralgija nepoznata učestalost mialgija nepoznata učestalost
English: Common dizziness
Croatian: Bulozni pemfigoid
English: - If you get any side effects, talk to your doctor, pharmacist, or nurse.
Croatian: - Ako primijetite bilo koju nuspojavu, potrebno je obavijestiti liječnika, ljekarnika ili medicinsku sestru.
English: EU/1/10/621/007 14 film-coated tablets EU/1/10/621/008 28 film-coated tablets EU/1/10/621/021 30 film-coated tablets EU/1/10/621/009 56 film-coated tablets EU/1/10/621/010 84 film-coated tablets EU/1/10/621/022 90 film-coated tablets EU/1/10/621/011 98 film-coated tablets EU/1/10/621/012 50 x 1 film-coated tablets
Croatian: EU/1/10/621/007 14 filmom obloženih tableta EU/1/10/621/008 28 filmom obloženih tableta EU/1/10/621/021 30 filmom obloženih tableta EU/1/10/621/009 56 filmom obloženih tableta EU/1/10/621/010 84 filmom obloženih tableta EU/1/10/621/022 90 filmom obloženih tableta EU/1/10/621/011 98 filmom obloženih tableta EU/1/10/621/012 50 x 1 filmom obložena tableta
English: nausea or vomiting) - any past or present kidney problems.
Croatian: - Bilo kakve tegobe s bubrezima sada ili u prošlosti.
English: EU/1/10/621/001 14 film-coated tablets EU/1/10/621/002 28 film-coated tablets EU/1/10/621/019 30 film-coated tablets EU/1/10/621/003 56 film-coated tablets EU/1/10/621/004 84 film-coated tablets EU/1/10/621/020 90 film-coated tablets EU/1/10/621/005 98 film-coated tablets EU/1/10/621/006 50 x 1 film-coated tablets
Croatian: EU/1/10/621/001 14 filmom obloženih tableta EU/1/10/621/002 28 filmom obloženih tableta EU/1/10/621/019 30 filmom obloženih tableta EU/1/10/621/003 56 filmom obloženih tableta EU/1/10/621/004 84 filmom obloženih tableta EU/1/10/621/020 90 filmom obloženih tableta EU/1/10/621/005 98 filmom obloženih tableta EU/1/10/621/006 50 x 1 filmom obložena tableta
English: If you get any side effects, talk to your doctor, pharmacist, or nurse.
Croatian: Ako primijetite bilo koju nuspojavu, potrebno je obavijestiti liječnika, ljekarnika ili medicinsku sestru.
English: Frequency not known back pain
Croatian: Učestalost nuspojave bol u leđima nepoznata učestalost artropatija nepoznata učestalost
English: Age did not have a clinically meaningful impact on the pharmacokinetics of sitagliptin based on a population pharmacokinetic analysis of Phase I and Phase II data.
Croatian: Prema analizi podataka populacijske farmakokinetike faze I i faze II, dob nema klinički značajnog utjecaja na farmakokinetiku sitagliptina.
English: Ristaben 25 mg film-coated tablets Sitagliptin
Croatian: Ristaben 25 mg filmom obložene tablete sitagliptin
English: Ristaben 25 mg film-coated tablets
Croatian: Ristaben 25 mg filmom obložene tablete
English: Ristaben 100 mg film-coated tablets
Croatian: Ristaben 100 mg filmom obložene tablete
English: Ristaben 50 mg film-coated tablets
Croatian: Ristaben 50 mg filmom obložene tablete
English: Tel: + 385 1 66 11 333 croatia_info@merck.com
Croatian: Merck Sharp & Dohme d.o.o. Tel: + 385 1 66 11 333 croatia_info@merck.com
English: Ristaben 100 mg film-coated tablets Sitagliptin
Croatian: Ristaben 100 mg filmom obložene tablete sitagliptin
English: Ristaben 50 mg film-coated tablets Sitagliptin
Croatian: Ristaben 50 mg filmom obložene tablete sitagliptin
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 100 mg sitagliptin.
Croatian: Jedna filmom obložena tableta (tableta) sadrži 100 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: Some patients have experienced different types of stomach discomfort when starting the combination of sitagliptin and metformin together (frequency is common).
Croatian: Pri uvođenju kombinacije sitagliptina i metformina neki su bolesnici imali različite vrste nelagoda u želucu (učestalost je česta).
English: Some patients have experienced the following side effects while taking sitagliptin in combination with pioglitazone and metformin:
Croatian: Pri uzimanju sitagliptina u kombinaciji s pioglitazonom i metforminom u nekih su bolesnika nastupile sljedeće nuspojave:
English: Sitagliptin is modestly dialysable.
Croatian: Sitagliptin se manjim dijelom može ukloniti dijalizom.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 25 mg sitagliptin.
Croatian: Jedna filmom obložena tableta (tableta) sadrži 25 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: Merck Sharp & Dohme B.V. Waarderweg 39
Croatian: Merck Sharp & Dohme B.V.
English: Each film-coated tablet (tablet) contains sitagliptin phosphate monohydrate, equivalent to 50 mg sitagliptin.
Croatian: Jedna filmom obložena tableta (tableta) sadrži 50 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: Sitagliptin is renally excreted.
Croatian: Sitagliptin se izlučuje bubrezima.
English: Minimal increases in QTc, not considered to be clinically relevant, were observed in one study at a dose of 800 mg sitagliptin.
Croatian: U jednom ispitivanju pri dozi od 800 mg sitagliptina opaženo je minimalno produljenje QTc-intervala koje se ne smatra klinički značajnim.
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 25 mg sitagliptin.
Croatian: Jedna tableta sadrži 25 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 100 mg sitagliptin.
Croatian: Jedna tableta sadrži 100 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: Each tablet contains sitagliptin phosphate monohydrate, equivalent to 50 mg sitagliptin.
Croatian: Jedna tableta sadrži 50 mg sitagliptina u obliku sitagliptinfosfat hidrata.
English: : +359 2 819 3737 info-msdbg@merck.com
Croatian: Мерк Шарп и Доум България ЕООД Тел.: +359 2 819 3737 info-msdbg@merck.com
English: Elderly
Croatian: Nuspojava
English: Renal and urinary disorders impaired renal function
Croatian: Poremećaji bubrega i mokraćnog sustava oštećenje funkcije bubrega nepoznata učestalost akutno zatajenje bubrega nepoznata učestalost
English: Usually treatment is short-term.
Croatian: Liječenje je obično kratkotrajno.
English: • The usual dose is one tablet daily.
Croatian: • Uobičajena doza je jedna tableta dnevno.
English: • ringing in the ears
Croatian: • zvonjava u ušima
English: Date of first authorisation: 15 June 2017
Croatian: Datum prvog odobrenja: 15 lipanj 2017
English: FACT (52 weeks)
Croatian: FACT (52 tjedna)
English: H-2900 Komárom Hungary
Croatian: H-2900 Komárom Mađarska
English: APEX (28 weeks)
Croatian: APEX (28 tjedana)
English: Combined Results
Croatian: Kombinirani rezultati
English: The potential risk for human is unknown.
Croatian: Moguć rizik kod ljudi nije poznat.
English: • muscle damage, a condition which on rare occasions can be serious.
Croatian: • oštećenje mišića, stanje koje u rijetkim slučajevima može biti ozbiljno.
English: Table 2 summarises the primary efficacy endpoint results:
Croatian: Tablica 2 daje sažet prikaz rezultata primarnih ishoda djelotvornosti:
English: Common***
Croatian: Često***
English: [For calendar blisters only]: MON
Croatian: [Samo za kalendarske blistere]: PON
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove, uključujući i one koje ste nabavili bez recepta.
English: Components of a multipack, can't be sold separately.
Croatian: Dio multipakiranja, ne smije se prodavati zasebno.
English: The back of the calendar blister pack is marked with the days of the week to help you check that you have taken a dose each day.
Croatian: Na stražnjoj strani kalendarskog blistera označeni su dani u tjednu, što će Vam pomoći da provjerite jeste li uzeli dozu svaki dan.
English: In most cases, these reactions occurred during the first month of therapy with febuxostat.
Croatian: U većini slučajeva su se te reakcije pojavile tijekom prvog mjeseca liječenja febuksostatom.
English: No interaction studies have been performed in humans.
Croatian: Nisu provedena ispitivanja interakcija u ljudi.
English: • increased sweating
Croatian: • pojačano znojenje
English: There was no significant increase in any other tumour type in either male or female mice or rats.
Croatian: Nije bilo značajnog povećanja incidencije tumora bilo kojeg drugog tipa, kako kod mužjaka tako i ženki miševa ili štakora.
English: Do not give this medicine to children under the age of 18 because the safety and efficacy have not been established.
Croatian: Ovaj lijek se ne smije davati djeci mlađoj od 18 godina jer sigurnost i djelotvornost u toj dobnoj skupini nije ustanovljena.
English: A risk to a suckling infant cannot be excluded.
Croatian: Ne može se isključiti rizik za dojenče.
English: [Blisters]
Croatian: [Blisteri]
English: Four pharmacologically active hydroxyl metabolites have been identified, of which three occur in plasma of humans.
Croatian: Identificirana su četiri farmakološki aktivna hidroksil metabolita, od kojih se tri pojavljuju u plazmi kod ljudi.
English: Overall 56.6% of patients discontinued trial treatment prematurely and 45% of patients did not complete all trial visits.
Croatian: Ukupno 56,6% bolesnika uključenih u ispitivanje prijevremeno je prekinulo liječenje, a 45% bolesnika nije napravilo sve posjete tijekom ispitivanja.
English: Do not stop taking Febuxostat Mylan without the advice of your doctor even if you feel better.
Croatian: Nemojte prestati uzimati Febuxostat Mylan bez savjetovanja s liječnikom, čak i ako se osjećate bolje.
English: Prophylaxis against gout flares was obligatory over the 26-week period.
Croatian: Profilaksa napada gihta bila je obvezna tijekom 26 tjedana.
English: Stop taking this medicine and contact your doctor immediately or go to an emergency department nearby if the following rare (may affect up to 1 in 1,000 people) side effects occur, because a serious allergic reaction might follow:
Croatian: Prestanite uzimati ovaj lijek i odmah se javite svom liječniku ili otiđite u najbližu ustanovu hitne medicinske pomoći ako se pojave sljedeće rijetke nuspojave (mogu se pojaviti kod manje od 1 na 1000 osoba), jer ozbiljna alergijska reakcija može slijediti nakon toga:
English: OUTER CARTON (BLISTERS AND BOTTLES)
Croatian: VANJSKA KUTIJA (BLISTERI I BOCE)
English: Not everyone gets flares, but you could get a flare-up even if you are taking Febuxostat Mylan, and especially during the first weeks or months of treatment.
Croatian: Napadi se neće pojaviti kod svih bolesnika, ali ih možete imati i ako uzimate Febuxostat Mylan, a posebno tijekom prvih tjedana ili mjeseci liječenja.
English: There is no appreciable accumulation when doses of 10 mg to 240 mg are administered every 24 hours.
Croatian: Ne dolazi do mjerljive akumulacije kad se doze od 10 mg do 240 mg primjenjuju svaka 24 sata.
English: Also contains lactose.
Croatian: Također sadrži laktozu.
English: It is especially important to tell your doctor or pharmacist if you are taking medicines containing any of the following substances as they may interact with Febuxostat Mylan and your doctor may wish to consider necessary measures:
Croatian: Posebno je važno da obavijestite svog liječnika ili ljekarnika ako uzimate lijekove koji sadrže neku od sljedećih tvari, s obzirom na to da one mogu stupiti u interakciju s lijekom Febuxostat Mylan i Vaš liječnik će možda morati poduzeti potrebne mjere:
English: • If you are allergic to febuxostat or any of the other ingredients of this medicine (listed in section 6).
Croatian: • ako ste alergični na febuksostat ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: Furthermore, the mean serum uric acid level was significantly lower with febuxostat since the first 24 hours of treatment and at any following time point.
Croatian: Nadalje, srednja razina serumske mokraćne kiseline bila je značajno niža s febuksostatom nakon prva 24 sata liječenja i u bilo kojoj točki vremena nakon toga.
English: Should you experience allergic reactions to Febuxostat Mylan, stop taking this medicine (see also section 4).
Croatian: Ako se pojavi alergijska reakcija na Febuxostat Mylan, prestanite uzimati ovaj lijek (vidjeti i dio 4).
English: About 69% of patients required no treatment change to achieve a final stable treatment.
Croatian: Kod oko 69% bolesnika nije bilo potrebno mijenjati liječenje kako bi se postigao stabilan učinak.
English: • The tablets should be taken by mouth and can be taken with or without food.
Croatian: • Tablete se uzimaju kroz usta i mogu se uzeti uz hranu ili bez nje.
English: • abnormal liver test results
Croatian: • abnormalni rezultati jetrenih pretraga
English: The safety and the efficacy of febuxostat in children aged below the age of 18 years have not been established.
Croatian: Sigurnost i djelotvornost febuksostata u djece do 18 godina nije ustanovljena.
English: • blurred vision, change in vision
Croatian: • zamagljen vid, promjene vida
English: • anaphylactic reactions, drug hypersensitivity (see also section 2 “Warnings and precautions”)
Croatian: • anafilaktičke reakcije, preosjetljivost na lijek (vidjeti i dio 2, „Upozorenja i mjere opreza“)
English: Medicinal products that inhibit glucuronidation, such as NSAIDs and probenecid, could in theory affect the elimination of febuxostat.
Croatian: Lijekovi koji inhibiraju glukuronidaciju, kao što su NSAIL-i i probenecid, teoretski bi mogli utjecati na eliminaciju febuksostata.
English: Libido decreased, insomnia Rare
Croatian: Smanjen libido, nesanica Rijetko
English: Your doctor might decide to permanently stop treatment with Febuxostat Mylan.
Croatian: - Vaš liječnik može odlučiti trajno prekinuti liječenje lijekom Febuxostat Mylan.
English: [Bottles]
Croatian: [Boce]
English: BL=baseline SEM=standard error of the mean
Croatian: BL = baseline (početak liječenja), SEM = standardna pogreška srednje vrijednosti
English: Where the combination cannot be avoided, a reduction of the dose of mercaptopurine/azathioprine is recommended.
Croatian: Kada se ova kombinacija ne može izbjeći preporučuje se sniženje doze merkaptopurina/azatioprina.
English: • abnormally low blood cell counts (white or red blood cells or platelets)
Croatian: • abnormalno nizak broj krvnih stanica (bijelih ili crvenih krvnih stanica ili krvnih pločica)
English: Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/foetal development or parturition (see section 5.3).
Croatian: Ispitivanja na životinjama ne ukazuju na izravne ili neizravne štetne učinke na trudnoću, embrionalni/fetalni razvoj i porođaj (vidjeti dio 5.3).
English: Your doctor may ask you to have blood tests to check that your liver is working normally.
Croatian: Liječnik može zatražiti da napravite krvne pretrage kako bi provjerio jetrenu funkciju.
English: • hair loss
Croatian: • opadanje kose
English: Febuxostat treatment should not be started until an acute attack of gout has completely subsided.
Croatian: Liječenje febuksostatom ne treba započeti prije nego što se akutni napad gihta potpuno ne smiri.
English: In general, febuxostat pharmacokinetic parameters estimated by these analyses are consistent with those obtained from healthy subjects, indicating that healthy subjects are representative for pharmacokinetic/pharmacodynamic assessment in the patient population with gout.
Croatian: Općenito, farmakokinetički parametri febuksostata čija je procjena rađena tim analizama konzistentni su s onima dobivenima kod zdravih ispitanika, što upućuje na to da su zdravi ispitanici reprezentativni za procjenu farmakokinetike/farmakodinamike u populaciji bolesnika koji boluju od gihta.
English: Your doctor will often prescribe other medicines, if they are needed, to help prevent or treat the symptoms of flares (such as pain and swelling in a joint).
Croatian: Liječnik će Vam često, ako je potrebno, propisati i druge lijekove koji će pomoći u sprječavanju ili liječenju simptoma napadaja gihta (kao što su bol i otok zgloba).
English: Patients should be advised of the signs and symptoms and monitored closely for symptoms of allergic/hypersensitivity reactions (see section 4.8).
Croatian: Bolesnike treba upozoriti na znakove i simptome te ih pomno pratiti radi pojave simptoma alergijskih reakcija/reakcija preosjetljivosti (vidjeti dio 4.8).
English: The Cmax and AUC of active metabolites increased up to 2- and 4-fold, respectively.
Croatian: Cmax i AUC aktivnih metabolita povećali su se do 2, odnosno 4 puta.
English: The effect of febuxostat on human fertility is unknown.
Croatian: Učinak febuksostata na plodnost u ljudi nije poznat.
English: The efficacy and safety of febuxostat in the prevention and treatment of Tumor Lysis Syndrome was evaluated in the FLORENCE (FLO-01) study.
Croatian: Djelotvornost i sigurnost febuksostata u prevenciji i liječenju sindroma tumorske lize su ocijenjeni u FLORENCE (FLO-01) ispitivanju.
English: Detailed information on this medicine is available on the European Medicines Agency website http://www.ema.europa.eu.
Croatian: Detaljnije informacije o ovom lijeku dostupne su na internetskoj stranici Europske agencije za lijekove http://www.ema.europa.eu.
English: Treatment of chronic hyperuricaemia
Croatian: Liječenje kronične hiperuricemije
English: • inflammation of the liver (hepatitis)
Croatian: • upala jetre (hepatitis)
English: Potent inducers of UGT enzymes might possibly lead to increased metabolism and decreased efficacy of febuxostat.
Croatian: Snažni induktori UGT enzima mogli bi dovesti do pojačana metabolizma i smanjene djelotvornosti febuksostata.
English: • difficulty in sleeping, sleepiness
Croatian: • smetnje spavanja, pospanost
English: It may also include ulcers in the mouth, throat, nose, genitals and conjunctivitis (red and swollen eyes).
Croatian: Također mogu biti prisutne ulceracije u ustima, ždrijelu, nosu i genitalijama te konjuktivitis (crvene i natečene oči).
English: Monitoring of serum uric acid is therefore recommended 1-2 weeks after start of treatment with a potent inducer of glucuronidation.
Croatian: Stoga se preporučuje praćenje mokraćne kiseline u serumu 1-2 tjedna nakon početka liječenja snažnim induktorima glukuronidacije.
English: Keep this medicine out of the sight and reach of children.
Croatian: • Lijek čuvajte izvan pogleda i dohvata djece.
English: Patients should exercise caution before driving, using machinery or participating in dangerous activities until they are reasonably certain that febuxostat does not adversely affect performance.
Croatian: Bolesnici trebaju postupati s oprezom tijekom upravljanja vozilima i strojevima i sudjelovanja u opasnim aktivnostima, sve dok nisu prilično sigurni da febuksostat kod njih ne utječe negativno na provedbu tih aktivnosti.
English: Long-term, open label extension Studies
Croatian: Dugotrajni, otvoreni produžeci ispitivanja
English: Atrial fibrillation, palpitations, ECG abnormal Rare
Croatian: Atrijska fibrilacija, palpitacije, abnormalni EKG Rijetko
English: What Febuxostat Mylan is and what it is used for What you need to know before you take Febuxostat Mylan How to take Febuxostat Mylan Possible side effects
Croatian: Što je Febuxostat Mylan i za što se koristi Što morate znati prije nego počnete uzimati Febuxostat Mylan Kako uzimati Febuxostat Mylan Moguće nuspojave
English: Febuxostat Mylan should be taken by mouth and can be taken with or without food.
Croatian: Febuxostat Mylan treba uzimati na usta i može se uzimati s hranom ili bez nje.
English: Talk to your doctor before taking Febuxostat Mylan:
Croatian: Obratite se svom liječniku prije nego uzmete Febuxostat Mylan:
English: In the event of an accidental overdose ask your doctor what to do, or contact your nearest accident and emergency department.
Croatian: U slučaju slučajna predoziranja, upitajte svog liječnika za savjet, ili se obratite najbližem odjelu za hitnu pomoć.
English: Pancreatitis, mouth ulceration
Croatian: Pankreatitis, ulceracije usta
English: However, weight-corrected Cmax and AUC were similar between the genders.
Croatian: Međutim, Cmax i AUC korigirani u odnosu na tjelesnu težinu bili su slični kod oba spola.
English: These findings are considered a consequence of species specific purine metabolism and urine composition and of no relevance to clinical use.
Croatian: Smatra se da su ovi nalazi posljedica metabolizma purina i sastava urina specifičnog za te vrste i nisu od značaja za kliničku primjenu.
English: These rates were similar to the rates reported on allopurinol (4.2%) (see section 4.4).
Croatian: Te su vrijednosti bile slične vrijednostima prijavljenima kod alopurinola (4,2%) (vidjeti dio 4.4).
English: This medicinal product does not require any special storage conditions.
Croatian: • Ovaj lijek ne zahtijeva posebne uvjete čuvanja.
English: Both steps in the above transformations are catalyzed by xanthine oxidase (XO).
Croatian: Oba koraka gore navedenih transformacija katalizirana su ksantin oksidazom (XO).
English: For any information about this medicine, please contact the local representative of the Marketing
Croatian: Za sve informacije o ovom lijeku obratite se lokalnom predstavniku nositelja odobrenja za stavljanje lijeka u promet:
English: The patients should be closely monitored and the dose of mercaptopurine/azathioprine should be subsequently adjusted based on the evaluation of the therapeutic response and the onset of eventual toxic effects.
Croatian: Bolesnike treba pozorno pratiti, a dozu merkaptopurina/azatioprina potom prilagoditi na osnovu procjene terapijskog odgovora i nastupa eventualnih toksičnih učinaka.
English: • increased level of creatine phosphokinase in blood (an indicator of muscle damage)
Croatian: • povišena razina kreatin fosfokinaze u krvi (pokazatelj oštećenja mišića)
English: Your doctor will have prescribed the strength most suitable for you.
Croatian: Vaš liječnik propisat će odgovarajuću jačinu tableta za Vas.
English: • weight decrease, increased appetite, uncontrolled loss of appetite (anorexia)
Croatian: • smanjenje tjelesne težine, pojačani apetit, nekontrolirani gubitak apetita (anoreksija)
English: Sudden cardiac death*
Croatian: Iznenadna srčana smrt*