FrancophonIA/ELRC3.0 huggingface dataset:
English: Due to similarities with emtricitabine, efavirenz/emtricitabine/tenofovir disoproxil should not be administered concomitantly with other cytidine analogues, such as lamivudine (see section 4.5).
Croatian: Zbog sličnosti s emtricitabinom, efavirenz/emtricitabin/tenofovirdizoproksil ne smije se primjenjivati istovremeno s drugim analozima citidina, kao što je lamivudin (vidjeti dio 4.5).
English: Elderly patients are more likely to have decreased hepatic or renal function, therefore caution should be exercised when treating elderly patients with efavirenz/emtricitabine/tenofovir disoproxil (see section 4.2).
Croatian: Kod starijih je osoba veća vjerojatnost da imaju smanjenu funkciju jetre ili bubrega pa je stoga nužan oprez kad se starije osobe liječe efavirenzom/emtricitabinom/tenofovirdizoproksilom (vidjeti dio 4.2).
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan is not recommended if you have moderate to severe kidney disease.
Croatian: Uzimanje lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan ne preporučuje se ako imate umjerenu ili tešku bolest bubrega.
English: Plasma concentrations and effects of warfarin or acenocoumarol are
Croatian: Efavirenz ima potencijal povećanja ili smanjenja koncentracija u plazmi i učinaka varfarina ili acenokumarola.
English: If the patient vomits more than 1 hour after taking Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan he/she does not need to take another dose.
Croatian: Ako bolesnik povraća nakon više od 1 sata od uzimanja lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, nije potrebno uzeti još jednu dozu.
English: 4 This adverse reaction was identified through post-marketing surveillance for either efavirenz, emtricitabine or tenofovir disoproxil.
Croatian: 4 Ova je nuspojava uočena tijekom nadzora koji je nakon stavljanja u promet vršen na efavirenzu, emtricitabinu ili tenofovirdizoproksilu.
English: Due to similarities with emtricitabine, efavirenz/emtricitabine/tenofovir disoproxil should not be administered concomitantly with other cytidine analogues, such as lamivudine.
Croatian: Zbog sličnosti s emtricitabinom, efavirenz/emtricitabin/tenofovirdizoproksil ne smije se primjenjivati istovremeno s drugim analozima citidina, kao što je lamivudin.
English: Efavirenz/emtricitabine/tenofovir disoproxil is not recommended for patients with moderate or severe renal impairment (creatinine clearance < 50 ml/min).
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil ne preporučuje se za bolesnike s umjerenim ili teškim oštećenjem funkcije bubrega (klirens kreatinina < 50 ml/min).
English: If you had a rash while taking another NNRTI, you may be at higher risk of getting a rash with Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan.
Croatian: Ako ste imali osip tijekom uzimanja drugog NNRTI lijeka, kod Vas postoji veći rizik od pojave osipa tijekom uzimanja lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan.
English: Discontinuation of efavirenz/emtricitabine/tenofovir disoproxil therapy in patients co-infected with HIV and HBV may be associated with severe acute exacerbations of hepatitis (see section 4.4).
Croatian: Prekid liječenja efavirenzom/emtricitabinom/tenofovirdizoproksilom u bolesnika istovremeno inficiranih HIV-om i HBV-om može biti povezan s teškim akutnim egzacerbacijama hepatitisa (vidjeti dio 4.4).
English: The pharmacokinetics of efavirenz, emtricitabine and tenofovir disoproxil after co-administration of the separate pharmaceutical forms or as efavirenz/emtricitabine/tenofovir disoproxil have not been studied in HIV infected patients with renal impairment.
Croatian: Farmakokinetika efavirenza, emtricitabina i tenofovirdizoproksila nakon njihove istovremene primjene kao zasebnih farmaceutskih oblika ili davanja u obliku efavirenza/emtricitabina/tenofovirdizoproksila nije istraživana u bolesnika inficiranim virusom HIV-a s oštećenjem funkcije bubrega.
English: There were no clinically significant pharmacokinetic interactions when efavirenz was administered with azithromycin, cetirizine, fosamprenavir/ritonavir, lorazepam, nelfinavir, zidovudine,
Croatian: Nema klinički značajnih farmakokinetičkih interakcija kada se efavirenz primjenjuje istovremeno s azitromicinom, cetirizinom, fosamprenavirom/ritonavirom, lorazepamom, nelfinavirom, zidovudinom, antacidima koji sadržavaju hidroksid aluminija/magnezija, famotidinom ili flukonazolom.
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan may make hormonal contraceptives less likely to work.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan može smanjiti učinkovitost hormonalnih kontraceptiva.
English: Lopinavir/ritonavir soft capsules or oral solution/Efavirenz
Croatian: lopinavir/ritonavir meke kapsule ili oralna otopina / efavirenz
English: While the clinical significance of decreased indinavir concentrations has not been established, the magnitude of the observed pharmacokinetic interaction should be taken into consideration when choosing a regimen containing both efavirenz, a component of efavirenz/emtricitabine/tenofovir disoproxil, and indinavir.
Croatian: Iako nije ustanovljen klinički značaj smanjenih koncentracija indinavira, prilikom odabira režima koji sadržava i efavirenz, komponentu efavirenza/emtricitabina/tenofovir dizoproksila, i indinavir nužno je uzeti u obzir opseg farmakokinetičke interakcije.
English: Your doctor may need to consider giving you a different anticonvulsant.
Croatian: Liječnik će možda morati razmotriti uvođenje drugog antikonvulziva.
English: AUC: ↓ 64% (↓ 62 to ↓ 67) Cmax: ↓ 46% (↓ 39 to ↓ 52) Cmin: ↓ 82% (↓ 79 to ↓ 85) Levonorgestrel (active metabolite):
Croatian: AUC: ↓ 64 % (↓ 62 do ↓ 67) Cmax: ↓ 46 % (↓ 39 do ↓ 52) Cmin: ↓ 82 % (↓ 79 do ↓ 85) levonorgestrel (aktivni metabolit):
English: AUC: ↓ 39% (↓ 30 to ↓ 46) Cmax: ↓ 26% (↓ 15 to ↓ 35) Clarithromycin 14hydroxymetabolite:
Croatian: AUC: ↓ 39 % (↓ 30 do ↓ 46) Cmax: ↓ 26 % (↓ 15 do ↓ 35) klaritromicin 14hidroksimetabolit:
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan should be administered with caution to elderly patients (see section 4.4).
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan starijim se osobama treba davati uz oprez (vidjeti dio 4.4).
English: No data are available to support the combination of efavirenz/emtricitabine/tenofovir disoproxil and other antiretroviral agents
Croatian: Nema dostupnih podataka koji bi poduprli primjenu kombinacije efavirenza/emtricitabina/tenofovirdizoproksila i drugih antiretrovirusnih tvari.
English: Ethinyloestradiol+Norgestimate/ Efavirenz (0.035 mg+0.25 mg q.d./600 mg q.d.)
Croatian: Peroralna primjena: etinilestradiol+norgestimat/efavirenz (0,035 mg +0,25 mg q.d./ 600 mg q.d.)
English: Didanosine: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil and didanosine is not recommended (see section 4.4 and Table 1).
Croatian: Didanozin: Ne preporučuje se istovremena primjena efavirenza/emtricitabina/tenofovirdizoproksila i didanozina (vidjeti dio 4.4 i Tablicu 1).
English: There were no clinically significant pharmacokinetic interactions when tenofovir disoproxil was co-administered with emtricitabine, nelfinavir or ribavirin.
Croatian: Nema klinički značajnih farmakokinetičkih interakcija kada se tenofovirdizoproksil primjenjuje istovremeno s emtricitabinom, nelfavinirom ili ribavirinom.
English: AUC: ↓ 34% (↓ 41 to ↓ 25) Cmax: ↓ 34% (↓ 41 to ↑ 25) Cmin: ↓ 34% (↓ 43 to ↑ 24) Sofosbuvir:
Croatian: AUC: ↓ 34 % (↓ 41 do ↓ 25) Cmax: ↓ 34 % (↓ 41 do ↑ 25) Cmin: ↓ 34 % (↓ 43 do ↑ 24) sofosbuvir:
English: St. John's wort (Hypericum perforatum): Co-administration of efavirenz/emtricitabine/tenofovir disoproxil and St. John's wort or herbal preparations containing St. John's wort is contraindicated.
Croatian: Gospina trava (Hypericum perforatum): Istovremena primjena efavirenza/emtricitabina/tenofovirdizoproksila i gospine trave ili biljnih preparata koji sadržavaju gospinu travu je kontraindicirana.
English: AUC: ↓ 35% (↓ 13 to ↓ 40) Cmax: ↓ 13% (↓ 0 to ↓ 23) 4-hydroxy atorvastatin:
Croatian: AUC: ↓ 35 % (↓ 13 do ↓ 40) Cmax: ↓ 13 % (↓ 0 do ↓ 23) 4-hidroksiatorvastatin:
English: Efavirenz: AUC: ↔
Croatian: efavirenz: AUC: ↔ Cmax: ↔
English: Do not take Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan:
Croatian: Nemojte uzimati Efavirenz/emtricitabin/tenofovirdizoproksil Mylan:
English: Severe rash associated with blistering, moist desquamation or ulceration has been reported in less than 1% of patients treated with efavirenz (see section 4.8).
Croatian: U manje od 1 % bolesnika liječenih efavirenzom zabilježen je teški oblik osipa s mjehurima, vlažna deskvamacija ili ulceracija (vidjeti dio 4.8).
English: Efavirenz/emtricitabine/tenofovir disoproxil can be reinitiated in patients interrupting therapy because of rash.
Croatian: Može se ponovo započeti s davanjem efavirenza/emtricitabina/tenofovirdizoproksila bolesnicima u kojih je terapija prekinuta zbog osipa.
English: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil and didanosine is not recommended since exposure to didanosine is significantly increased following co-administration with tenofovir disoproxil that may increase the risk of didanosine-related adverse reactions (see section 4.5).
Croatian: Ne preporučuje se istovremena primjena efavirenza/emtricitabina/tenofovirdizoproksila i didanozina jer se izloženost didanozinu značajno povećava u slučaju istodobne primjene tenofovirdizoproksila, što može povećati rizik od nuspojava povezanih s didanozinom (vidjeti dio 4.5).
English: What you need to know before you take Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan
Croatian: Što morate znati prije nego počnete uzimati Efavirenz/emtricitabin/tenofovirdizoproksil Mylan
English: Ethinyloestradiol/Tenofovir disoproxil (-/245 mg q.d.)
Croatian: etinilestradiol/tenofovirdizoproksil (−/245 mg q.d.)
English: AUC: ↔ Cmax: ↔ Emtricitabine: AUC: ↔ Cmax: ↔
Croatian: AUC: ↔ Cmax: ↔ emtricitabin: AUC: ↔ Cmax: ↔
English: AUC: ↑ 49% C12h: ↑ 3%
Croatian: C12h: ↑ 3 %
English: If the patient vomits within 1 hour of taking Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan, another tablet should be taken.
Croatian: U slučaju da bolesnik povraća unutar 1 sata od uzimanja lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, treba uzeti još jednu tabletu.
English: Co-administration of ritonavir at doses of 600 mg and efavirenz/emtricitabine/tenofovir disoproxil is not recommended.
Croatian: Ne preporučuje se istovremena primjena ritonavira u dozama od 600 mg s efavirenzom/emtricitabinom/tenof ovirdizoproksilom.
English: Where discontinuation of therapy with one of the components of efavirenz/emtricitabine/tenofovir disoproxil is indicated or where dose modification is necessary, separate preparations of efavirenz, emtricitabine and tenofovir disoproxil are available.
Croatian: Kada je indiciran prekid terapije jednom od komponenti lijeka efavirenz/emtricitabin/tenofovirdizoproksil ili ako je potrebno prilagoditi dozu, postoje odvojeni pripravci efavirenza, emtricitabina i tenofovirdizoproksila.
English: Common hypertriglyceridaemia3 hyperglycaemia, hypertriglyceridaemia
Croatian: hiperglikemija, hipertrigliceridemija
English: Prior efavirenz/emtricitabine/tenofovir disoproxil components (N=299)
Croatian: Prethodno liječenje komponentama efavirenza/emtricitabina/tenofovirdizoproksila (N = 299)
English: Since efavirenz/emtricitabine/tenofovir disoproxil is a fixed-dose combination product, the dose of efavirenz cannot be altered; therefore, voriconazole and efavirenz/emtricitabine/tenofovir disoproxil must not be coadministered.
Croatian: Budući da je efavirenz/emtricitabin/tenofovirdi zoproksil lijek s fiksnom kombinacijom doza, doza efavirenza se ne može mijenjati, što znači da se vorikonazol i efavirenz/emtricitabin/tenofovirdi zoproksil ne smiju primjenjivati istovremeno.
English: Microcrystalline cellulose Silica, colloidal anhydrous Sodium metabisulfite Lactose monohydrate Iron oxide red (E172)
Croatian: Jezgra tablete karmelozanatrij, umrežena hidroksipropilceluloza djelomično supstituirana hidroksipropilceluloza magnezijev stearat mikrokristalična celuloza silicijev dioksid, koloidni bezvodni natrijev metabisulfit laktoza hidrat crveni željezov oksid (E172)
English: Where discontinuation of therapy with one of the components of Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan is indicated or where dose modification is necessary, separate preparations of efavirenz, emtricitabine and tenofovir disoproxil are available.
Croatian: Kada je indiciran prekid terapije jednom od komponenti lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan ili ako je potrebno prilagoditi dozu, postoje odvojeni pripravci efavirenza, emtricitabina i tenofovirdizoproksila.
English: Recommendation concerning coadministration with efavirenz/emtricitabine/tenofovir disoproxil (efavirenz 600 mg, emtricitabine 200 mg, tenofovir disoproxil 245 mg)
Croatian: Preporuka za istovremenu primjenu s efavirenzom/ emtricitabinom/ tenofovirdizoproksilom (efavirenz 600 mg, emtricitabin 200 mg, tenofovirdizoproksil 245 mg)
English: AUC: ↓ 36% (↓ 32 to ↓ 40) Cmax: ↓ 21% (↓ 15 to ↓ 26) Cmin: ↓ 47% (↓ 41 to ↓ 53) (decrease in carbamazepine concentrations: CYP3A4 induction; decrease in efavirenz concentrations: CYP3A4 and CYP2B6 induction) Co-administration of higher doses of either efavirenz or
Croatian: AUC: ↓ 36 % (↓ 32 do ↓ 40) Cmax: ↓ 21 % (↓ 15 do ↓ 26) Cmin: ↓ 47 % (↓ 41 do ↓ 53) (smanjenje koncentracija karbamazepina: indukcija CYP3A4; smanjenje koncentracija efavirenza: indukcija CYP3A4 i CYP2B6) Istovremena primjena viših doza efavirenza ili karbamazepina nije ispitana.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each film-coated tablet contains 600 mg of efavirenz, 200 mg of emtricitabine and 245 mg of tenofovir disoproxil (as maleate).
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedna filmom obložena tableta sadržava 600 mg efavirenza, 200 mg emtricitabina i 245 mg tenofovirdizoproksila (u obliku maleata).
English: Elderly: efavirenz/emtricitabine/tenofovir disoproxil has not been studied in patients over the age of 65.
Croatian: Starije osobe: efavirenz/emtricitabin/tenofovirdizoproksil nije se ispitivao u bolesnika starijih od 65 godina.
English: *lower than recommended dose
Croatian: * manje od preporučene doze darunavir:
English: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil and didanosine is not recommended (see section 4.4).
Croatian: Ne preporučuje se istovremena primjena efavirenza/emtricitabina/tenofovir dizoproksila i didanozina (vidjeti dio 4.4).
English: As a fixed combination, efavirenz/emtricitabine/tenofovir disoproxil should not be administered concomitantly with other medicinal products containing the same active components, emtricitabine or tenofovir disoproxil.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil se, kao fiksna kombinacija, ne smije primjenjivati istovremeno s drugim lijekovima koji sadržavaju iste aktivne sastojke, emtricitabin ili tenofovirdizoproksil.
English: 2 This adverse reaction may occur as a consequence of proximal renal tubulopathy.
Croatian: 2 Ova nuspojava može nastati kao posljedica proksimalne bubrežne tubulopatije.
English: The following side effects are very common (these may affect more than 1 in 10 patients)
Croatian: Sljedeće nuspojave su vrlo česte (mogu se pojaviti u više od 1 na 10 bolesnika):
English: Do not breast-feed during treatment with Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan.
Croatian: Nemojte dojiti tijekom liječenja lijekom Efavirenz/emtricitabin/tenofovirdizoproksil Mylan.
English: - if you are currently taking any of the following medicines (see also “Other Medicines and Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan”): - astemizole or terfenadine (used to treat hay fever or other allergies) - bepridil (used to treat heart disease) - cisapride (used to treat heartburn) - elbasvir/grazoprevir (used to treat hepatitis C) - ergot alkaloids (for example, ergotamine, dihydroergotamine, ergonovine, and methylergonovine) (used to treat migraines and cluster headaches) - midazolam or triazolam (used to help you sleep) - pimozide, imipramine, amitriptyline or clomipramine (used to treat certain mental conditions) - St. John's wort (Hypericum perforatum) (a herbal preparation used for depression and anxiety) - voriconazole (used to treat fungal infections) - flecainide, metoprolol (used to treat irregular heart beat) - certain antibiotics (macrolides, fluoroquinolones, imidazole) - triazole antifungal agents - certain antimalarial agents - methadone (used to treat opiate addiction)
Croatian: - ako trenutno uzimate bilo koji od sljedećih lijekova (pogledajte također Drugi lijekovi i Efavirenz/emtricitabin/tenofovirdizoproksil Mylan): - astemizol ili terfenadin (koriste se za liječenje peludne groznice i drugih alergija) - bepridil (koristi se za liječenje bolesti srca) - cisaprid (koristi se za liječenje žgaravice) - elbasvir/grazoprevir (koristi se za liječenje hepatitisa C) - ergot alkaloidi (na primjer, ergotamin, dihidroergotamin, ergonovin i metilergonovin)
English: Rarely, pancreatitis and lactic acidosis, sometimes fatal, have been reported.
Croatian: Postoje izvješća o rijetkim slučajevima pankreatitisa i laktacidoze, ponekad smrtnog ishoda.
English: AUC: ↓ 71% (↓ 67 to ↓ 74) Cmax: ↓ 51% (↓ 46 to ↓ 56) Cmin: ↓ 91% (↓ 88 to ↓ 92) Efavirenz:
Croatian: AUC: ↓ 71 % (↓ 67 do ↓ 74) Cmax: ↓ 51 % (↓ 46 do ↓ 56) Cmin: ↓ 91 % (↓ 88 do ↓ 92) efavirenz:
English: No dose adjustment of rifampicin is recommended when given with efavirenz/emtricitabine/tenofovir disoproxil.
Croatian: Ne preporučuje se prilagođavanje doze rifamipicina kada se primjenjuje s efavirenzom/emtricitabinom/tenof ovirdizoproksilom.
English: Methadone/Tenofovir disoproxil (40-110 mg q.d./245 mg q.d.)
Croatian: metadon/tenofovirdizoproksil (40 - 110 mg q.d./ 245 mg q.d.)
English: AUC: ↓ 39% (↓ 21 to ↓ 53) Cmax: ↓ 37% (↓ 20 to ↓ 51) Cmin: ↓ 44% (↓ 27 to ↓ 58) (decrease in itraconazole concentrations: CYP3A4 induction)
Croatian: AUC: ↓ 39 % (↓ 21 do ↓ 53) Cmax: ↓ 37 % (↓ 20 do ↓ 51) Cmin: ↓ 44 % (↓ 27 do ↓ 58) (smanjenje koncentracija itrakozanola: indukcija CYP3A4) hidroksiitrakonazol:
English: Co-administration with voriconazole.
Croatian: Istovremena primjena s vorikonazolom.
English: Co-administration of efavirenz/emtricitabine/tenofovir disoproxil with sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/voxilaprevir is not recommended (see section 4.4).
Croatian: Primjena efavirenza/emtricitabina/tenofovir dizoproksila zajedno sa sofosbuvirom/velpatasvirom ili sofosbuvirom/velpatasvirom/voks ilaprevirom se ne preporučuje (vidjeti dio 4.4).
English: Other medicines and Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan
Croatian: Drugi lijekovi i Efavirenz/emtricitabin/tenofovirdizoproksil Mylan
English: Therefore coadministration of atazanavir/ritonavir and efavirenz/emtricitabine/tenofovir disoproxil is not recommended (see Table 1).
Croatian: Iz tog se razloga ne preporučuje istovremena primjena atazanavira/ritonavira i efavirenza/emtricitabina/tenofovirdizoproksila (vidjeti Tablicu 1).
English: AUC: ↓ 43% (↓ 34 to ↓ 50) Cmax: ↓ 12% (↓ 1 to ↓ 26) 2-hydroxy atorvastatin:
Croatian: AUC: ↓ 43 % (↓ 34 do ↓ 50) Cmax: ↓ 12 % (↓ 1 do ↓ 26) 2-hidroksiatorvastatin:
English: The administration of efavirenz/emtricitabine/tenofovir disoproxil with food may increase efavirenz exposure (see section 5.2) and may lead to an increase in frequency of adverse reactions (see section 4.8).
Croatian: Uzimanje efavirenza/emtricitabina/tenofovirdizoproksila s hranom može povećati izloženost efavirenzu (vidjeti dio 5.2) te može dovesti do povećane učestalosti nuspojava (vidjeti dio 4.8).
English: It is important not to miss a dose of Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan.
Croatian: Važno je da ne propustite uzeti dozu lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan.
English: Dose adjustments of diltiazem when co-administered with efavirenz/emtricitabine/tenofovir disoproxil should be guided by clinical response (refer to the Summary of Product Characteristics for diltiazem).
Croatian: Podešavanja doze diltiazema kada se primjenjuje istovremeno s efavirenzom/emtricitabinom/tenof ovirdizoproksilom treba usklađivati s kliničkim odgovorom (pogledajte sažetak opisa svojstava lijeka za diltiazem).
English: AUC: ↓ 53% (↓ 61 to ↓ 43) Cmax: ↓ 47% (↓ 57 to ↓ 36) Cmin: ↓ 57% (↓ 64 to ↓ 48) Efavirenz:
Croatian: AUC: ↓ 53 % (↓ 61 do ↓ 43) Cmax: ↓ 47 % (↓ 57 do ↓ 36) Cmin: ↓ 57 % (↓ 64 do ↓ 48) efavirenz:
English: Since efavirenz/emtricitabine/tenofovir disoproxil is a fixed-dose combination product, the dose of efavirenz cannot be altered; therefore, voriconazole and efavirenz/emtricitabine/tenofovir disoproxil must not be co-administered (see section 4.3 and Table 1).
Croatian: Budući da je efavirenz/emtricitabin/tenofovirdizoproksil lijek s fiksnom kombinacijom doza, doza efavirenza se ne može mijenjati, što znači da se vorikonazol i efavirenz/emtricitabin/tenofovirdizoproksil ne smiju primjenjivati istovremeno (vidjeti dio 4.3 i Tablicu 1).
English: Tacrolimus/Emtricitabine/Tenofovir disoproxil (0.1 mg/kg q.d./200 mg/245 mg q.d.)
Croatian: takrolimus/emtricitabin/tenofovirdizo proksil (0,1 mg/kg q.d./ 200 mg/245 mg q.d.)
English: Protease inhibitors Atazanavir/ritonavir/Tenofovir disoproxil (300 mg q.d./100 mg q.d./245 mg q.d.)
Croatian: Antivirusni lijekovi protiv HIV-a Inhibitori proteaze atazanavir/ritonavir/tenofovirdizopro ksil (300 mg q.d./ 100 mg q.d./ 245 mg q.d.)
English: AUC: ↓ 69% (↓ 55 to ↓ 79) Cmax: ↓ 60% (↓ 50 to ↓ 68) Cmin: ↓ 63% (↓ 44 to ↓ 75) Desacetyl diltiazem:
Croatian: AUC: ↓ 69 % (↓ 55 do ↓ 79) Cmax: ↓ 60 % (↓ 50 do ↓ 68) Cmin: ↓ 63 % (↓ 44 do ↓ 75) desacetildiltiazem:
English: Barrier contraception should always be used in combination with other methods of contraception (for example, oral or other hormonal contraceptives, see section 4.5) while on therapy with efavirenz/emtricitabine/tenofovir disoproxil.
Croatian: Tijekom terapije efavirenzom/emtricitabinom/tenofovirdizoproksilom barijerna kontracepcija se uvijek treba koristiti u kombinaciji s drugim metodama kontracepcije (na primjer, oralnim ili drugim hormonalnim kontraceptivima, vidjeti dio 4.5).
English: Indinavir/Tenofovir disoproxil (800 mg q8h/245 mg q.d.)
Croatian: indinavir/tenofovirdizoproksil (800 mg q8h / 245 mg q.d.)
English: Simeprevir/Tenofovir disoproxil (150 mg q.d./245 mg q.d.)
Croatian: simeprevir/tenofovirdizoproksil (150 mg q.d./ 245 mg q.d.)
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan can reduce the amount of the anticonvulsant in your blood.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan može smanjiti koncentraciju antikonvulziva u krvi.
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan can reduce the amount of itraconazole or posaconazole in your blood.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan može smanjiti količinu itrakonazola ili posakonazola u krvi.
English: It is recommended that Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan be taken on an empty stomach since food may increase efavirenz exposure and may lead to an increase in the frequency of adverse reactions (see sections 4.4 and 4.8).
Croatian: Preporučuje se uzimanje efavirenza/emtricitabina/tenofovirdizoproksila na prazan želudac jer hrana može povećati izloženost efavirenzu i može dovesti do povećane učestalosti nuspojava (vidjeti dio 4.4 i 4.8).
English: Bupropion/Emtricitabine
Croatian: bupropion/emtricitabin
English: Concomitant administration of atovaquone/proguanil with efavirenz/emtricitabine/tenofovir disoproxil should be avoided.
Croatian: Istodobnu primjenu atovakvona/progvanila s efavirenzom/emtricitabinom/tenof ovirdizoproksilom treba izbjegavati.
English: NAME OF THE MEDICINAL PRODUCT Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan 600 mg/200 mg/245 mg film-coated tablets
Croatian: NAZIV LIJEKA Efavirenz/emtricitabin/tenofovirdizoproksil Mylan 600 mg/200 mg/245 mg filmom obložene tablete
English: Artemether/Lumefantrine/Emtricitabine Interaction not studied.
Croatian: artemeter/lumefantrin/emtricitabin Interakcija nije ispitana. artemeter/lumefantrin/tenofovirdizopr oksil
English: CARDIOVASCULAR AGENTS Calcium Channel Blockers Diltiazem/Efavirenz (240 mg q.d./600 mg q.d.)
Croatian: Blokatori kalcijevih kanala diltiazem/efavirenz (240 mg q.d./ 600 mg q.d.)