FrancophonIA/ELRC3.0 huggingface dataset:
English: Therefore, the CHMP maintained its previous recommendation that the change to the marketing authorisation be refused.
Lithuanian: Dėl šios priežasties CHMP nepakeitė savo ankstesnės rekomendacijos neleisti keisti rinkodaros leidimo.
English: In the study, patients received Avastin or placebo (a dummy treatment) in addition to treatment with radiotherapy and temozolomide.
Lithuanian: Tyrimo metu pacientai, kurie buvo gydomi spinduline terapija ir temozolomidu, papildomai vartojo Avastin arba placebą (netikrą vaistą).
English: It is available as a concentrate that is made up into a solution for infusion (drip into a vein).
Lithuanian: Avastin tiekiamas koncentrato, iš kurio ruošiamas infuzinis (į veną lašinamas) tirpalas, forma.
English: circulates in the blood and makes blood vessels grow.
Lithuanian: kurio kraujagyslės auga, - ir jungtųsi prie jo.
English: --1 Porcine circovirus type 2 ORF2 subunit antigen ≥4.5 log2 ELISA units* * Antibody titre obtained according to the in vivo potency test in chickens
Lithuanian: --1 2 tipo kiaulių cirkovirusų ORF2 subvienetų antigenų ne mažiau kaip 4,5 log2 ELISA vienetų* * Antikūnų titras pagal in vivo stiprumo tyrimą vištoms.
English: MA (EU) number
Lithuanian: ES numeris
English: The average accumulation factor is about 1.7.
Lithuanian: Kaupimosi faktorius yra maždaug 1,7.
English: “Recent” here means between 12 hours and 10 days.
Lithuanian: „Neseniai“ reiškia 12 valand - 10 dien laikotarpyje;
English: In addition:
Lithuanian: Papildomai:
English: The mean treatment duration was two years.
Lithuanian: Vidutin gydymo trukm buvo du metai.
English: What Diovan is and what it is used for Before you take Diovan How to take Diovan Possible side effects How to store Diovan Further information
Lithuanian: Kas yra Diovan ir kam jis vartojamas Kas žinotina prieš vartojant Diovan Kaip vartoti Diovan Galimas šalutinis poveikis Kaip laikyti Diovan Kita informacija
English: PHARMACEUTICAL FORM
Lithuanian: FARMACIN FORMA
English: • if you have severe heart disease other than heart failure or heart attack.
Lithuanian: • jeigu sergate sunkia širdies liga, kita nei širdies nepakankamumas ar širdies priepuolis;
English: Side effects in children and adolescents are similar to those seen in adults.
Lithuanian: Vaikams ir paaugliams pasireiškiantis šalutinis poveikis b na panašus atsirandant suaugusiesiems žmonms.
English: These side effects may occur with certain frequencies, which are defined as follows: very common: affects more than 1 user in 10 common: affects 1 to 10 users in 100 uncommon: affects 1 to 10 users in 1,000 rare: affects 1 to 10 users in 10,000 very rare: affects less than 1 user in 10,000 not known: frequency cannot be estimated from the available data.
Lithuanian: Šis šalutinis poveikis gali pasireikšti tam tikru dažnumu, kuris apibr žiamas taip: labai dažnai: paveikia daugiau kaip 1 vartotoj iš 10; dažnai: paveikia nuo 1 iki 10 vartotoj iš 100; nedažnai: paveikia nuo 1 iki 10 vartotoj iš 1 000; retai: paveikia nuo 1 iki 10 vartotoj iš 10 000; labai retai: paveikia mažiau kaip 1 vartotoj iš 10 000; dažnis nežinomas: (negali b ti vertintas pagal turimus duomenis).
English: If you get any of these, see a doctor immediately.
Lithuanian: Jei Jums pasireišk kuris nors iš ši reiškini , nedelsdami kreipkits gydytoj.
English: PHARMACEUTICAL PARTICULARS 6.1 List of excipients [To be completed nationally] 6.2 Incompatibilities [To be completed nationally] 6.3 Shelf life [To be completed nationally] 6.4 Special precautions for storage [To be completed nationally] 6.5 Nature and contents of container [To be completed nationally] 6.6 Special precautions for disposal No special requirements.
Lithuanian: FARMACIN INFORMACIJA 6.1 Pagalbini medžiag s rašas [Pildyti savo šalies kalba] 6.2 Nesuderinamumas [Pildyti savo šalies kalba] 6.3 Tinkamumo laikas [Pildyti savo šalies kalba] 6.4 Specialios laikymo s lygos [Pildyti savo šalies kalba] 6.5 Pakuot ir jos turinys [Pildyti savo šalies kalba] 6.6 Special s reikalavimai atliekoms tvarkyti Speciali reikalavim n ra.
English: The antihypertensive effect is substantially present within 2 weeks, and maximal effects are attained within 4 weeks.
Lithuanian: Antihipertenzinis poveikis realiai pasireiškia per 2 savaites, o didžiausias efektas pasiekiamas per 4 savaites.
English: The final dose depends on what you as an individual patient can tolerate.
Lithuanian: Galutins dozs dydis priklausys nuo to, koki doz tas pacientas gals toleruoti.
English: Additional information on special populations
Lithuanian: Papildoma informacija specialioms asmen grup ms
English: Laboratório Normal-Produtos Farmacêuticos, Lda Rua do Centro Empresarial, Edificio 8 Quinta da Beloura
Lithuanian: Laboratório Normal-Produtos Farmacêuticos, Lda Rua do Centro Empresarial,
English: It is caused when the heart muscle cannot pump blood strongly enough to supply all the blood needed throughout the body.
Lithuanian: Taip atsitinka, kai širdis nepaj gia išstumti tiek kraujo, kad apr pint juo visus organus.
English: The mean duration of follow-up was nearly two years.
Lithuanian: Tiriamieji buvo sekami vidutiniškai beveik du metus.
English: Recent myocardial infarction
Lithuanian: Neseniai patirtas miokardo infarktas
English: Adverse reactions are ranked by frequency, the most frequent first, using the following convention: very common ( 1/10); common ( 1/100 to <1/10); uncommon ( 1/1,000 to <1/100); rare ( 1/10,000 to <1/1,000) very rare (<1/10,000), including isolated reports.
Lithuanian: Nepageidaujamos reakcijos išd stytos pagal dažn , pirmiausia - dažniausiai pasitaikan ios, pagal toki tvark : labai dažnos ( 1/10), dažnos (nuo 1/100 iki < 1/10), nedažnos (nuo 1/1 000 iki < 1/100), retios (nuo 1/10 000 iki < 1/1 000), labai retos (< 1/10 000), skaitant pavienius atvejus.
English: The rats in the juvenile valsartan study were dosed up to day 70, and effects on renal maturation (postnatal 4-6 weeks) cannot be excluded.
Lithuanian: Tyrimo metu valsartano jauniems žiurkiukams girdyta ne ilgiau kaip iki 70 gyvenimo dienos, poveikio inkst brendimui (4-6 postnatalin savait) atmesti negalima.
English: The mean daily dose of Diovan in Val-HeFT was 254 mg.
Lithuanian: Val-HeFt tyrimo metu vidutin Diovan paros doz buvo 254 mg.
English: Swallow Diovan with a glass of water.
Lithuanian: Diovan nurykite, užsigerdami stikline vandens.
English: Important information about some of the ingredients of Diovan [To be completed nationally]
Lithuanian: Svarbi informacija apie kai kurias pagalbines Diovan medžiagas [Pildyti savo šalies kalba]
English: The half-life of valsartan is 6 hours.
Lithuanian: Valsartano pusin s eliminacijos laikas yra 6 valandos.
English: • to treat adult patients after a recent heart attack (myocardial infarction).
Lithuanian: • gydyti suaugusiuosius žmones, kuriems neseniai vyko širdies priepuolis (miokardo infarktas).
English: The primary endpoint was time to all-cause mortality.
Lithuanian: Pirminis vertinamosios baigties kriterijus buvo laikas iki mirties d l bet kokios priežasties.
English: Overall, the dosedependent antihypertensive effect of valsartan was consistent across all the demographic subgroups.
Lithuanian: Apskritai nuo doz s priklausomas antihipertenzinis valsartano poveikis buvo panašus visuose demografiniuose pogrupiuose.
English: If symptomatic hypotension or renal dysfunction occur, consideration should be given to a dose reduction.
Lithuanian: Jei stebimas simptominis kraujosp džio sumaž jimas arba atsiranda inkst funkcijos sutrikimas, reikia apsvarstyti doz s mažinim .
English: Method of administration Diovan may be taken independently of a meal and should be administered with water.
Lithuanian: Vartojimo metodas Diovan galima vartoti nepriklausomai nuo valgio, vaistin preparat reikia išgerti su vandeniu.
English: Therefore, monitoring of renal function at the beginning of the treatment is recommended, as well as adequate hydration of the patient.
Lithuanian: Tod l gydymo pradžioje rekomenduojama sekti inkst funkcij , o taip pat pacientui skirti pakankamai skys i .
English: Non-steroidal anti-inflammatory medicines (NSAIDs), including selective COX-2 inhibitors, acetylsalicylic acid >3 g/day), and non-selective NSAIDs
Lithuanian: Nesteroidiniai vaistai nuo uždegimo (NVNU), skaitant selektyvius COX-2 inhibitorius, acetilsalicilo r gšt (> 3 g per par ) ir neselektyvius NVNU
English: The dose should be adjusted based on blood pressure response.
Lithuanian: Doz reikia koreguoti atsižvelgiant kraujosp džio reakcij .
English: Consideration should be given to reducing the dose of concomitant diuretics.
Lithuanian: Reikia apsvarstyti kartu skiriam diuretik doz s mažinim .
English: Like all medicines, Diovan can cause side effects, although not everybody gets them.
Lithuanian: Diovan, kaip ir kiti vaistai, gali sukelti šalutin poveik , nors jis pasireiškia ne visiems žmon ms.
English: Elderly No dose adjustment is required in elderly patients.
Lithuanian: Senyvo amžiaus pacientai Senyvo amžiaus pacientams doz s koreguoti nereikia.
English: Baseline therapy included ACE inhibitors (93%), diuretics (86%), digoxin (67%) and beta blockers (36%).
Lithuanian: Pradiniam gydymui taikyti AKF inhibitoriai (93 %), diuretikai (86 %), digoksinas (67 %) ir beta adrenoblokatoriai (36 %).
English: In a subgroup of patients not receiving an ACE inhibitor (n=366), the morbidity benefits were greatest.
Lithuanian: Pacient , kuriems nebuvo skiriamas AKF inhibitorius, pogrupyje (n=366) nauda, vertinant sergamum , buvo didžiausia.
English: The addition of a diuretic such as hydrochlorothiazide will decrease blood pressure even further in these patients.
Lithuanian: Papildomai skiriant diuretik , pavyzdžiui, hidrochlorotiazido, šiems pacientams netgi dar labiau sumaž ja kraujosp dis.
English: Overall, the three dose levels of valsartan (low, medium and high) significantly reduced systolic blood pressure by 8, 10, 12 mm Hg from the baseline, respectively.
Lithuanian: Apskritai visos trys valsartano doz s (maža, vidutin ir didel ) reikšmingai sumažino sistolin kraujosp d nuo pradinio rodmens (atitinkamai 8 mm Hg, 10 mm Hg ir 12 mm Hg).
English: Composite mortality and morbidity risk was significantly reduced by 18.3% (95% CI: 8% to 28%) with valsartan compared with placebo (31.0% vs. 36.3%).
Lithuanian: Sud tin mirtingumo ir sergamumo rizika reikšmingai sumaž jo 18,3 % (95 % PI: nuo 8 % iki 28 %) skiriant valsartan , lyginant su placebu (31,0 % ir 36,3 %).
English: All cause mortality was similar (p=NS) in the valsartan (19.7%) and placebo (19.4%) groups.
Lithuanian: Mirtingumas d l bet kokios priežasties valsartano (19,7 %) ir placebo (19,4 %) grup se buvo panašus (p=NS).
English: • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Lithuanian: • Jeigu pasireišk sunkus šalutinis poveikis arba pasteb jote šiame lapelyje nenurodyt šalutin poveik , pasakykite gydytojui arba vaistininkui.
English: The primary benefit was a 27.5% (95% CI: 17 to 37%) reduction in risk for time to first heart failure hospitalisation (13.9% vs. 18.5%).
Lithuanian: Gauta pirmin nauda buvo: 27,5 % (95 % CI: nuo 17 iki 37 %) sutrump jo rizikos laikas iki pirmo patekimo ligonin d l širdies nepakankamumo (13,9 % ir 18,5 %).
English: • to treat symptomatic heart failure in adult patients.
Lithuanian: • gydyti simptomin širdies nepakankamum suaugusiesiems žmon ms.
English: The target maximum dose is 160 mg twice daily.
Lithuanian: Didžiausia tikslin doz yra 160 mg du kartus per par .
English: In patients receiving an ACE inhibitor without a beta-blocker, all cause mortality was similar (p=NS) in the valsartan (21.8%) and placebo (22.5%) groups.
Lithuanian: Pacient , kuriems buvo skiriamas AKF inhibitorius ir neskiriama beta adrenoblokatori , mirtingumas d l bet kokios priežasties buvo panašus (p=NS) valsartano (21,8 %) ir placebo (22,5 %) grup se.
English: AUC and Cmax values of valsartan are almost proportional with increasing dose over the clinical dosing range (40 to 160 mg twice a day).
Lithuanian: Valsartano AUC ir Cmax did jimas yra beveik proporcingas doz s dydžiui, terapini dozi ribose (2 kartus per par vartojant 40-160 mg doz ).
English: Consequently, a clinical relevance in children <1 year of age cannot be excluded, while preclinical data do not indicate a safety concern for children older than 1 year.
Lithuanian: Vadinasi, klinikin s tokio poveikio reikšm s < 1 met vaikams paneigti negalima, ta iau ikiklinikiniai duomenys saugumo problem , galin i atsirasti vyresniems kaip 1 met vaikams, nerodo.
English: In a second study in which 75 children aged 1 to 6 years were randomised, no significant liver transaminase elevations or death occurred with valsartan treatment.
Lithuanian: Antro atsitiktini im i tyrimo, kuriame dalyvavo 75 vaikai 1-6 met amžiaus, metu valsartano vartojusiems pacientams reikšmingo kepen transaminazi aktyvumo padid jimo ar mirties atvej nebuvo.
English: In patients with mild to moderate hepatic impairment without cholestasis, the dose of valsartan should not exceed 80 mg.
Lithuanian: Ligoniams, kuriems yra lengvas arba vidutinio sunkumo kepen funkcijos sutrikimas be cholestaz s, valsartano doz turi neviršyti 80 mg.
English: QUALITATIVE AND QUANTITATIVE COMPOSITION
Lithuanian: KOKYBIN IR KIEKYBIN SUD TIS
English: • if you are more than 3 months pregnant (it is also better to avoid Diovan in early pregnancy - see pregnancy section).
Lithuanian: • jeigu esate n š ia daugiau kaip tris m nesius (taip pat geriau nevartoti Diovan ankstyvuoju n štumo laikotarpiu) arba kr timi maitinate k dik - žr.
English: This medicinal product is authorised in the Member States of the EEA under the following names: [To be completed nationally]
Lithuanian: Šis pakuot s lapelis paskutin kart patvirtintas Šis vaistinis preparatas yra registruotas šalyse nar se Europos ekonomin je zonoje sekan iais pavadinimais: [Pildyti savo šalies kalba]
English: What Diovan looks like and contents of the pack [To be completed nationally]
Lithuanian: Diovan išvaizda ir kiekis pakuot je [Pildyti savo šalies kalba]
English: If any of these apply to you, tell your doctor before you take Diovan.
Lithuanian: poskyr ,,N štumo ir žindymo laikotarpis“). Jei bent vienas iš ši teigini tinka Jums, prieš vartodami Diovan, apie tai praneškite gydytojui.
English: Diovan can be given together with other treatment for heart attack, and your doctor will decide which treatment is suitable for you.
Lithuanian: Diovan galima vartoti kartu su kitais vaistais, skirtais širdies priepuolio gydymui; J s gydytojas nusprs, kuris vaistas Jums tinka.
English: The study report will be finalized by Q4 2010.
Lithuanian: Galutin tyrimo ataskaita bus parengta iki 2010 m.
English: Read all of this leaflet carefully before you start taking this medicine.
Lithuanian: Atidžiai perskaitykite vis š lapel , prieš prad dami vartoti vaist .
English: This applies particularly when valsartan is given in the presence of other conditions (fever, dehydration) likely to impair renal function.
Lithuanian: Tai ypatingai svarbu, kai valsartano skiriama pacientams, kuriems yra kitoki inkst funkcij galini bloginti bkli (karšiavimas, dehidracija).
English: This combination apparently increases the risk for adverse events and is therefore not recommended.
Lithuanian: Skiriant š derin akivaizdžiai padid ja nepageidaujam reiškini atsiradimo rizika, tod l tai daryti nerekomenduojama.
English: Reductions in systolic blood pressure were comparable in patients receiving valsartan (15 mmHg) and enalapril (14 mm Hg) (non-inferiority p-value <0.0001).
Lithuanian: Sistolinis kraujosp dis panašiai sumaž jo ir valsartano (15 mm Hg), ir enalaprilio (14 mm Hg) vartojusiems ligoniams (nenusileidimo p rodmuo <0,0001).
English: Valsartan may be used in patients treated with other post-myocardial infarction therapies, e.g. thrombolytics, acetylsalicylic acid, beta blockers, statins, and diuretics.
Lithuanian: Valsartan gali vartoti pacientai, kuriems po miokardo infarkto skiriamas kitas gydymas, pavyzdžiui, tromboliziniai preparatai, acetilsalicilo r gštis, beta adrenoblokatoriai, statinai ir diuretikai.
English: For maximum doses studied in clinical trials please refer to the table below.
Lithuanian: Didžiausios klinikini tyrim metu vartotos doz s nurodytos žemiau esan ioje lentel je.
English: At 30 weeks, the percentage change in UAE was significantly reduced by 36% from baseline with valsartan 160 mg (95%CI: 22 to 47%), and by 44% with valsartan 320 mg (95%CI: 31 to 54%).
Lithuanian: Per 30 savai i procentinis AIŠ pokytis, lyginant su pradiniu, skiriant 160 mg valsartano, reikšmingai sumaž jo 36 % (95 % PI: nuo 22 iki 47 %) ir 44 %, skiriant 320 mg valsartano (95 % PI: nuo 31 iki 54 %).
English: Daily oral dosing of neonatal/juvenile rats (from a postnatal day 7 to postnatal day 70) with valsartan at doses as low as 1 mg/kg/day (about 10-35% of the maximum recommended paediatric dose of 4 mg/kg/day on systemic exposure basis) produced persistent, irreversible kidney damage.
Lithuanian: Kasdien tik atsivestiems ir jauniems žiurkiukams (7-70 dien po atsivedimo) girdyta ne mažesn kaip 1 mg/kg k no svorio valsartano paros doz (maždaug 10-35 % maksimalios vaikams ir paaugliams rekomenduojamos 4 mg/kg k no svorio paros doz s, skai iuojant pagal sistemin ekspozicij ) suk l nuolatin nepraeinant inkst pažeidim .
English: • if you are treated after a heart attack or for heart failure, your doctor may check your kidney function.
Lithuanian: • jeigu neseniai po širdies priepuolio arba d l širdies nepakankamumo Jums buvo skirtas gydymas, gydytojas tur t patikrinti, kaip veikia J s inkstai;
English: Children and adolescents (6 to 18 years of age) with high blood pressure In patients who weigh less than 35 kg the usual dose is 40 mg of valsartan once daily.
Lithuanian: 6-18 met vaikai ir paaugliai, kuri kraujosp dis didelis prasta vien kart per par vartojama valsartano doz mažiau kaip 35 kg sveriantiems pacientams yra 40 mg.
English: Irrespective of treatment, mortality was lower in the group of patients treated with a beta blocker, suggesting that the known beta blocker benefit in this population was maintained in this trial.
Lithuanian: Nepriklausomai nuo vartojam medikament , mirtingumas buvo mažesnis beta adrenoblokatori vartojusi pacient grup je, vadinasi, pastarieji preparatai tirtiems ligoniams buvo naudingi ir šio tyrimo metu.
English: Following oral administration of valsartan alone, peak plasma concentrations of valsartan are reached in 24 hours with tablets and 1-2 hours with solution formulation.
Lithuanian: Išg rus vien tiktai valsartano, didžiausia vaisto koncentracija plazmoje pasiekiama per 2-4 valandas, jei vartojama table i , ir per 1-2 valandas, jei vartojama tirpalo.
English: Treatment of clinically stable adult patients with symptomatic heart failure or asymptomatic left ventricular systolic dysfunction after a recent (12 hours-10 days) myocardial infarction (see sections 4.4 and 5.1).
Lithuanian: Gydymas suaugusi j pacient , kuri klinikin b kl stabili ir kurie serga simptominiu širdies nepakankamumu arba jiems pasireiškia besimptomis kairiojo skilvelio sistolin s funkcijos sutrikimas po neseniai vykusio miokardo infarkto (prieš 12 valand - 10 dien ) (žr. 4.4 ir 5.1 skyrius).
English: The recommended starting dose of Diovan is 40 mg twice daily.
Lithuanian: Rekomenduojama pradin Diovan doz yra 40 mg du kartus per par .
English: The maximum daily dose administered in clinical trials is 320 mg in divided doses.
Lithuanian: Klinikini tyrim metu didžiausia paros doz yra 320 mg, skiriama per kelis kartus.
English: In heart failure patients:
Lithuanian: Pacientai, kuriems yra širdies nepakankamumas
English: In some cases your doctor may prescribe higher doses (the dose can be increased to 160 mg and to a maximum of 320 mg).
Lithuanian: Tam tikrais atvejais gydytojas gali skirti didesnes dozes (doz gali b ti padidinta iki 160 mg ir maksimalios 320 mg doz s).
English: Uptitration to 80 mg and 160 mg twice daily should be done at intervals of at least two weeks to the highest dose, as tolerated by the patient.
Lithuanian: Titravimas iki 80 mg ir 160 mg doz s du kartus per par , turi b ti atliekamas ne re iau kaip kas dvi savaites, iki didžiausios doz s, kuri gali toleruoti pacientas.
English: The initial dose is 40 mg once daily for children weighing below 35 kg and 80 mg once daily for those weighing 35 kg or more.
Lithuanian: Mažiau kaip 35 kg sveriantiems vaikams pradin vartojama doz yra 40 mg vien kart per par , o sveriantiems 35 kg ar daugiau - 80 mg vien kart per par .
English: This reduction in AUC is not, however, accompanied by a clinically significant reduction in the therapeutic effect, and valsartan can therefore be given either with or without food.
Lithuanian: Taiau šis AUC sumažjimas nra susijs su reikšmingu terapinio veiksmingumo maž jimu, tod l valsartan galima vartoti tiek su maistu, tiek nevalgius.
English: Not all pack sizes may be marketed
Lithuanian: Gali b ti tiekiamos ne vis dydži pakuot s
English: A hydroxy metabolite has been identified in plasma at low concentrations (less than 10% of the valsartan AUC).
Lithuanian: Valsartanas n ra intensyviai biologiškai transformuojamas, metabolizuojama tik 20 % doz s. valsartano hidroksi- metabolito kraujo plazmoje b na mažai (mažiau negu 10 % valsartano AUC).
English: Results appearing to favour placebo (composite mortality and morbidity was 21.9% in placebo vs. 25.4% in valsartan group) were observed for those patients receiving the triple combination of an ACE inhibitor, a beta blocker and valsartan.
Lithuanian: Palankesni rezultatai gauti placebo grup je (sud tinis mirtingumas ir sergamumas placebo grup je buvo 21,9 %, o valsartano grup je - 25,4 %), stebint tuos pacientus, kuriems buvo skiriama trij vaist derinys: AKF inhibitorius, beta adrenoblokatorius ir valsartanas.
English: • fever, sore throat or mouth ulcers due to infections (symptoms of low level of white blood cells also called neutropenia)
Lithuanian: • karš iavimas, gerkl s skausmas arba opel s burnoje d l infekcij (leukocit kiekio sumaž jimo, dar vadinamo neutropenija, požymiai);
English: Val-HeFT was a randomised, controlled, multinational clinical trial of valsartan compared with placebo on morbidity and mortality in 5,010 NYHA class II (62%), III (36%) and IV (2%) heart failure patients receiving usual therapy with LVEF <40% and left ventricular internal diastolic diameter (LVIDD) >2.9 cm/m2.
Lithuanian: Val-HeFT atsitiktini im i , kontrolinio, tarptautinio klinikinio tyrimo metu buvo lyginta valsartano ir placebo taka 5 010 pacient , sirgusi II (62 %), III (36 %) ar IV (2 %) funkcin s klas s (pagal NYHA) širdies funkcijos nepakankamumu, kurie buvo gydomi prastais medikamentais, ir kuri kairiojo širdies skilvelio išmetimo frakcija (KSIF) buvo < 40 %, o kairiojo skilvelio vidinis skersmuo (KSVS) diastol s metu buvo > 2,9 cm/m2, ligotumui ir mirtingumui.
English: Evaluation of post-myocardial infarction patients should always include assessment of renal function (see section 4.2).
Lithuanian: Vertinant pacient b kl po miokardo infarkto, taip pat visada reikia vertinti ir inkst funkcij (žr. 4.2 skyri ).
English: Provas 40 mg 40 mg
Lithuanian: Provas 40 mg
English: ADRs that occurred in adult patients with post-myocardial infarction and/or heart failure patients are listed below.
Lithuanian: Toliau išvardytos NR, kurios pasitaik suaugusiesiems pacientams po miokardo infarkto ir (arba) tiems, kuriems buvo širdies nepakankamumas.
English: In this subgroup all-cause mortality was significantly reduced with valsartan compared to placebo by 33% (95% CI: -6% to 58%) (17.3% valsartan vs. 27.1% placebo) and the composite mortality and morbidity risk was significantly reduced by 44% (24.9% valsartan vs. 42.5% placebo).
Lithuanian: Šiame pogrupyje mirtingumas d l bet kokios priežasties reikšmingai sumaž jo valsartano grup je, lyginant su placebo, 33 % (95 % PI: nuo -6 % iki 58 %) (17,3 % valsartano grup je, lyginant su 27,1 % placebo grup je) sud tin mirtingumo ir sergamumo rizika reikšmingai sumaž jo 44 % (24,9 % valsartano grup je, lyginant su 42,5 % placebo grup je).
English: Provas 80 mg 80 mg
Lithuanian: Provas 80 mg