FrancophonIA/ELRC3.0 huggingface dataset:
English: The CHMP was concerned that it was not possible to establish the benefits of the treatment combinations including Taxotere/Docetaxel Winthrop when used in addition to surgery, because of the way the single main study was designed.
Estonian: Inimravimite komitee oli arvamusel, et Taxotere/Docetaxel Winthropit sisaldavate ravimikombinatsioonide kasulikkust nende kasutamisel lisaks operatsioonile ei saa põhiuuringu ülesehituse tõttu välja selgitada.
English: Taxotere/Docetaxel Winthrop is also used in advanced or metastatic non-small cell lung cancer, in prostate cancer, in metastatic gastric adenocarcinoma (a type of stomach cancer) and in advanced head and neck cancer.
Estonian: Taxotere/Docetaxel Winthropit kasutatakse ka kaugelearenenud või siiretega mitteväikerakulise kopsuvähi, eesnäärmevähi, siiretega mao adenokartsinoomi (maovähi liik) ja pea- ja kaelapiirkonna kaugelearenenud vähi korral.
English: Taxotere/Docetaxel Winthrop is an anticancer medicine.
Estonian: Taxotere/Docetaxel Winthrop on vähiravim.
English: In these patients, Taxotere/Docetaxel Winthrop is used in addition to surgery to remove the tumour, together with doxorubicin and cyclophosphamide (other anticancer medicines).
Estonian: Neil patsientidel kasutatakse Taxotere/Docetaxel Winthropit koos doksorubitsiini ja tsüklofosfamiidiga (teised vähiravimid) lisaks operatsioonile, et eemaldada kasvaja.
English: The active substance in Taxotere/Docetaxel Winthrop, docetaxel, belongs to the group of anticancer medicines known as the ‘taxanes'.
Estonian: Taxotere/Docetaxel Winthropi toimeaine dotsetakseel kuulub vähiravimite taksaanide rühma.
English: How is Taxotere/Docetaxel Winthrop expected to work?
Estonian: Milline on Taxotere/Docetaxel Winthropi eeldatav toime?
English: 183 11 Täby Sweden
Estonian: 183 11 Täby Rootsi
English: 0401 Oslo, Norway
Estonian: 0401 Oslo, Norra
English: 1800 Vilvoorde Belgium
Estonian: 1800 Vilvoorde Belgia
English: 635 00 Brno Czech republic
Estonian: 635 00 Brno Tšehhi
English: Wincentego st. Pola 21 58-500, Jelenia Góra, Poland
Estonian: Wincentego st. Pola 21 58-500, Jelenia Góra, Poola
English: Brno Czech Republic
Estonian: Brno Tšehhi
English: 41 Chalton street, London, NW1 1JD, United Kingdom
Estonian: 41 Chalton street, London, NW1 1JD, UÜhendkuningriik
English: Parque Empresarial San Fernando San Fernando de Henares Madrid 28830 spain
Estonian: Parque Empresarial San Fernando San Fernando de Henares Madrid 28830 Hispaania
English: Sanofi Aventis France 1-13 boulevard Romain Rolland
Estonian: Sanofi Aventis Prantsusmaa 1-13 boulevard Romain Rolland
English: 18th km Athens-Lamia National Road 146 71 Nea Erythrea Greece
Estonian: 18th km Athens-Lamia National Road 146 71 Nea Erythrea Kreeka
English: D-06796 Brehna Germany
Estonian: D-06796 Brehna Saksamaa
English: 140 00 Czech Republic
Estonian: 140 00 Tšehhi
English: Slovak Republic ratiopharm International GmbH
Estonian: Slovakkia ratiopharm International GmbH
English: Novartis Norge AS, Postboks 4284 Nydalen
Estonian: Novartis Norge AS, Postboks 4284
English: List of the names, pharmaceutical forms, strengths of the medicinal products, routes of administration, marketing authorisation holders in the member states
Estonian: I lisa Ravimite nimetuste, ravimvormide, tugevuste, manustamisviiside, müügiloa hoidjate loetelu liikmesriikides
English: Laboratoire Pharmy II Strategy center 26 rue des Gaudines 78100 Saint Germain en Laye - France
Estonian: Laboratoire Pharmy II Strategy center 26 rue des Gaudines 78100 Saint Germain en Laye - Prantsusmaa
English: PHARMACEUTICALS LTD. 425 Irakliou Avenue, 14122 Atena, Grecia
Estonian: PHARMACEUTICALS LTD. 425 Irakliou Avenue, 14122 Atena, Kreeka
English: 92300 Levallois-PerretFrance
Estonian: 92300 Levallois-PerretPrantsusmaa
English: Zambon France 13 rue René Jacques 92138 Issy les Moulineaux CedexFrance
Estonian: Zambon Prantsusmaa 13 rue René Jacques 92138 Issy les Moulineaux CedexPrantsusmaa
English: Cediat Mediffusion 11 bis rue du Colisée 75008 Paris - France
Estonian: Cediat Mediffusion 11 bis rue du Colisée 75008 ParisPrantsusmaa
English: 75014 Paris - France
Estonian: 75014 ParisPrantsusmaa
English: 200UI/1d.
Estonian: 200 IU /1d.
English: Germany mibe GmbH Arzneimittel Münchener Str. 15
Estonian: Saksamaa mibe GmbH Arzneimittel Münchener Str. 15
English: 61118 Bad Vilbel, Germany
Estonian: 61118 Bad Vilbel, Saksamaa
English: D-83607 Holzkirchen Germany
Estonian: D-83607 Holzkirchen Saksamaa
English: TAD Pharma GmbH Heinz-Lohmann-Str. 5 D-27472 Cuxhaven Germany
Estonian: TAD Pharma GmbH Heinz-Lohmann-Str. 5 D-27472 Cuxhaven Saksamaa
English: Novartis Finland Oy Metsänneidonkuja 10 02130 Espoo Finland
Estonian: Novartis Soome Oy Metsänneidonkuja 10 02130 Espoo Soome
English: D-61118 Bad Vilbel Germany
Estonian: D-61118 Bad Vilbel Saksamaa
English: ALFA WASSERMANN, S.P.A.Via Enrico Fermi, 1 Alanno Scalo (Pescaro) 65020 ITALIA
Estonian: ALFA WASSERMANN, S.P.A.Via Enrico Fermi, 1 Alanno Scalo (Pescaro) 65020 Itaalia
English: Novartis Pharma SAS 2-4 rue Lionel Terray 92500 Rueil-MalmaisonFrance
Estonian: Novartis Pharma SAS 2-4 rue Lionel Terray 92500 Rueil-MalmaisonPrantsusmaa
English: D-89079 Ulm Germany
Estonian: D-89079 Ulm Saksamaa
English: LABORATORIO PADRO, S.A.Gran Via de les Corts Catalanes, 764 barcelona 08013 Spain
Estonian: LABORATORIO PADRO, S.A.Gran Via de les Corts Catalanes, 764 barcelona 08013
English: Osteodon 200 IU.
Estonian: Osteodon 200 I.U.
English: Novartis Healthcare A/S, Lyngbyvej 172, DK2100, København Ø, Denmark
Estonian: Novartis Healthcare A/S, Lyngbyvej 172, DK2100, København Ø, Taani
English: D-22946 Trittau Germany
Estonian: D-22946 Trittau Saksamaa
English: Germany ratiopharm GmbH Graf-Arco-Str. 3 D-89079 Ulm Germany
Estonian: Saksamaa ratiopharm GmbH Graf-Arco-Str. 3 D-89079 Ulm Saksamaa
English: Novartis Healthcare A/S, Lyngbyvej 172, DK-2100 Østerbro, Denmark
Estonian: Novartis Healthcare A/S, Lyngbyvej 172, DK-2100 Østerbro, Taani
English: Calcitonin-CT 100 I.E./0,1ml Nasenspray 100 IU / dose
Estonian: Calcitonin-CT 100 I.E./0,1ml Nasenspray 100 I.U.
English: FARMACEUTICA, S.A.Gran Via de les Corts Catalanes, 764 Barcelona 08013 Spain
Estonian: NOVARTIS FARMACEUTICA, S.A.Gran Via de les Corts Catalanes, 764 Barcelona 08013 Hispaania
English: D-90429 Nürnberg, Germany
Estonian: D-90429 Nürnberg, Saksamaa
English: 2200 i.e./ml
Estonian: 100 I.U./ML
English: Gentsesteenweg 615 1080 Brussels Belgium
Estonian: Nycomed Belgia sca/cva Gentsesteenweg 615 1080 Brussels Belgia
English: D-90429 Nürnberg Germany
Estonian: D-90429 Nürnberg Saksamaa
English: TONOCALCIN 100 IU nosová aerodisperzia 100 IU/0,1 ml
Estonian: TONOCALCIN 100 IU nosová aerodisperzia 100 IU/0,1 ml ninasprei, lahus
English: SANOFI AVENTIS, S.A.Josep Plá, 2
Estonian: SANOFI AVENTIS, S.A.Josep Plá, 2 Barcelona 08019 Hispaania
English: Czech Republic
Estonian: Tšehhi
English: Miacalcic Nasal 200 Nasal Spray Solution 200IU/dose
Estonian: Miacalcic Nasal 200 Ninasprei Solution 200IU/dose
English: 200 IU / metered dose
Estonian: 200 IU/ metered dose ninasprei, lahus
English: Miacalcic 400 IU /2ml Solution for Injection and infusion
Estonian: Miacalcic 400 IU /2ml Süstelahus and infusion
English: The Netherlands
Estonian: Holland
English: Novartis Pharma GmbH, Roonstrasse 25, Nurnberg 90429, Germany
Estonian: Novartis Pharma GmbH, Roonstrasse 25, Nurnberg 90429, Saksamaa
English: Slovak Republic
Estonian: Slovakkia
English: Calcitonina Wander 200 200 IU/dose nebuliser solution nasal use
Estonian: Calcitonina Wander 200 200 U.I./dose nebuliseeritav lahus intranasaalne
English: OSPOR 200 UI solución para pulverización nasal 200 IU
Estonian: OSPOR 200 UI solución para pulverización nasal 200 UI
English: Pharmaceuticals Uk Ltd, Frimley Business Park, Frimley, Camberley, Surrey, UK
Estonian: Pharmaceuticals Uk Ltd, Frimley Business Park, Frimley, Camberley, Surrey, Ühendkuningriik
English: NOVARTIS PHARMA GmbH,Roonstrasse 25D90429 Nürnberg, Germania
Estonian: NOVARTIS PHARMA GmbH,Roonstrasse 25D90429 Nürnberg, Saksamaa
English: Novartis Pharma GmbH, Roonstrasse 25, D90429 Nuernberg, Germany
Estonian: Novartis Pharma GmbH, Roonstrasse 25, D90429 Nuernberg, Saksamaa
English: MIACALCIC NASAL 200 200 IU/dose
Estonian: Miacalcic Nasal 200 200 IU/dose ninasprei
English: Calcitonin 'Novartis' 50 I.E./ml - Lösung zur Injektion und Infusion solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: Calcitonin 'Novartis' 50 I.E./ml - Lösung zur Injektion und Infusion
English: Pharmaceuticals UK Ltd, Frimley, Camberley, Surrey GU16 7SR, UK
Estonian: Pharmaceuticals UK Ltd, Frimley, Camberley, Surrey GU16 7SR, Ühendkuningriik
English: 200 IU/dose, 2000 IU/ML
Estonian: 200 I.U./dose, 2000 I.U./ML
English: 0,25 mg powder and solvent for solution for injection intramuscular use, intravenous use, subcutaneous use
Estonian: 0,25 mg süstelahuse pulber ja lahusti intramuskulaarne, intravenoosne, subkutaanne
English: 100 IU/1ML AMP solution for injection intramuscular use
Estonian: 100 IU/1ML AMP süstelahus intramuskulaarne
English: Calcitonine Pharmy II 50 IU/ml solution for injection intramuscular use, intravenous use, subcutaneous use
Estonian: Calcitonine Pharmy II 50 IU/ml süstelahus intramuskulaarne, intravenoosne, subkutaanne
English: Calcitonine Pharmy II 100 IU/ml solution for injection intramuscular use, intravenous use, subcutaneous use
Estonian: Calcitonine Pharmy II 100 IU/ml süstelahus intramuskulaarne, intravenoosne, subkutaanne
English: Calcitonin 'Novartis' 100 I.E./ml - Lösung zur Injektion und Infusion solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: Calcitonin 'Novartis' 100 I.E./ml - Lösung zur Injektion und Infusion
English: Pharmaceuticals UK Ltd. Frimley Business Park, Frimley Camberley, Surrey GU16 7SR, United Kingdom
Estonian: Pharmaceuticals UK Ltd. Frimley Business Park, Frimley Camberley, Surrey GU16 7SR, Ühendkuningriik
English: 0,50 mg powder and solvent for solution for injection intramuscular use, intravenous use, subcutaneous use
Estonian: 0,50 mg süstelahuse pulber ja lahusti intramuskulaarne, intravenoosne, subkutaanne
English: 200IU in 1ml
Estonian: 200IU in 1ml ninasprei, lahus
English: TONOCALCIN 200 IU nosová aerodisperzia 200 IU/0,1 ml
Estonian: TONOCALCIN 200 IU nosová aerodisperzia
English: 50 IU/1ML AMP solution for injection intravenous use, intramuscular use, subcutaneous use
Estonian: 50 IU/1ML AMP süstelahus intravenoosne, intramuskulaarne, subkutaanne
English: pre-filled syringe subcutaneous use, intramuscular use, intravenous use
Estonian: eeltäidetud süstal subkutaanne, intramuskulaarne, intravenoosne
English: CALCITONINA SANDOZ 50 UI/ml solution for injection and infusion intravenous use, intramuscular use, subcutaneous use
Estonian: CALCITONINA SANDOZ 50 IU /ml süste- ja infusioonilahus intravenoosne, intramuskulaarne, subkutaanne
English: Novartis Pharma B.V. Raapopseweg 1
Estonian: Novartis Pharma B.V.
English: MIACALCIC 100 NE/ml oldatos injekció és infúzió solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: MIACALCIC 100 NE/ml oldatos injekció és infúzió
English: Calcitonine-Sandoz 100 IE/ml, oplossing voor injectie en infusie solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: Calcitonine-Sandoz 100 IE/ml, oplossing voor injectie en infusie
English: 100 i.e./ml solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: 100 i.e./ml süste- ja infusioonilahus subkutaanne, intramuskulaarne, intravenoosne
English: solution for injection subcutaneous use, intramuscular use, intravenous use
Estonian: süstelahus subkutaanne, intramuskulaarne, intravenoosne
English: solution for injection/infusion intravenous use, intramuscular use, subcutaneous use
Estonian: süste- ja infusioonilahus intravenoosne, intramuskulaarne, subkutaanne
English: CALCITONINA SANDOZ 100 UI/ml solution for injection and infusion intravenous use, intramuscular use, subcutaneous use
Estonian: CALCITONINA SANDOZ 100 IU /ml süste- ja infusioonilahus intravenoosne, intramuskulaarne, subkutaanne
English: 100 IU/1ML AMP solution for injection intravenous use, intramuscular use, subcutaneous use
Estonian: 100 IU/1ML AMP süstelahus intravenoosne, intramuskulaarne, subkutaanne
English: MIACALCIC 50 NE/ml oldatos injekció és infúzió solution for injection/infusion subcutaneous use, intramuscular use, intravenous use
Estonian: MIACALCIC 50 NE/ml oldatos injekció és infúzió
English: CALCO 50 NE/ml injekció solution for injection subcutaneous use, intramuscular use, intravenous use
Estonian: 50 IU/ml süste- ja infusioonilahus subkutaanne, intramuskulaarne, intravenoosne
English: 100 UI/ml solution for injection intravenous use, intramuscular use, subcutaneous use
Estonian: 100 UI/ml süstelahus intramuskulaarne, intravenoosne, subkutaanne
English: solution for injection intramuscular use, subcutaneous use
Estonian: süstelahus intramuskulaarne, subkutaanne
English: 100 IU/1ML AMP solution for injection intramuscular use, subcutaneous use
Estonian: 100 IU/1ML AMP süstelahus intramuskulaarne, subkutaanne
English: Miacalcic 50 IU/1 ml solution for injection, concentrate for solution for infusion subcutaneous use, intramuscular use, intravenous use
Estonian: 50 IU/1 ml süstelahus, infusioonilahuse kontsentraat subkutaanne, intramuskulaarne, intravenoosne
English: Subcutaneous use
Estonian: Süstelahus subkutaanne
English: 200 IU /dose
Estonian: 200 IU/dose ninasprei, lahus
English: 50 UI/ml solution for injection intravenous use, intramuscular use, subcutaneous use
Estonian: 50 IU /ml süstelahus intravenoosne, intramuskulaarne, subkutaanne
English: Miacalcic Nasal 200 200 IU/dose nasal spray nasal use
Estonian: MIACALCIC NASAL 200 200 I.U./dose ninasprei, lahus
English: 100 IE/1 ml solution for injection subcutaneous use, intramuscular use
Estonian: 100 IU/1 ml süstelahus subkutaanne, intramuskulaarne
English: powder and solvent for solution for injection intramuscular use, subcutaneous use
Estonian: süstelahuse pulber ja lahusti intramuskulaarne, subkutaanne
English: blister (alu/alu)
Estonian: Blister (Al/Al)
English: Pack size bottle (HDPE)
Estonian: Pudel (HDPE)
English: Strength Pharmaceutical Form
Estonian: Tugevus Ravimvorm Manustamistee Sisepakendi iseloomustus
English: Immediate Packaging
Estonian: Pakendi suurus
English: EMEA Number
Estonian: EMEA protseduuri number
English: Medicinal Product no longer authorised
Estonian: Ravimil on müügiluba lõppenud
English: Administration
Estonian: Süstelahus Subkutaanseks
English: Route of Administration vial (glass)
Estonian: Müügiloa nr Euroopa Liidus viaal (klaas)
English: 1 vial + 1 syringe + 2 alcohol pads
Estonian: 1 viaal + 1 süstal + 2 alkoholipadjakest
English: 1 pre-filled syringe + 1 alcohol pad
Estonian: 1 eeltäidetud süstal + 1 alkoholipadjake
English: 1 pre-filled pen + 1 alcohol pad in a blister
Estonian: 1 pensüstel + 1 alkoholipadjake blistris
English: 1 pre-filled syringe with needleguard + 1 alcohol pad
Estonian: 1 nõelakaitsega eeltäidetud süstal + 1 alkoholipadjake
English: Always take this medicine exactly as your doctor has told you.
Estonian: Võtke seda ravimit alati täpselt nii nagu arst on teile selgitanud.
English: System Organ Class
Estonian: Organsüsteemide klass
English: How to take <invented name>
Estonian: Kuidas <Väljamõeldud nimetus> võtta
English: Children and adolescents <invented name> is not recommended in children aged below 18 years.
Estonian: Lapsed ja noorukid <Väljamõeldud nimetus> ei soovitata kasutada alla 18-aastastel lastel.
English: If you have kidney problems or if you are older than 75 years old, your doctor may adjust the recommended dose.
Estonian: Kui teil on neeruprobleemid või te olete üle 75-aastane, võib arst teie annust kohandada.
English: Driving and using machines
Estonian: Autojuhtimine ja masinatega töötamine:
English: Hepatitis
Estonian: Hepatiit
English: [the currently approved indications should be deleted and replaced by the following]
Estonian: [hetkel kinnitatud vastunäidustused tuleb kustutada ja asendada järgmisega]
English: The safety and efficacy of trimetazidine in children aged below 18 years have not been established.
Estonian: Lapsed Trimetasidiini ohutust ja efektiivsust alla 18-aastastel lastel ei ole tõestatud.
English: Acute generalized exanthematus pustulosis (AGEP), angioedema
Estonian: Akuutne generaliseerunud eksantematoosne pustuloos (AGEP), angioödeem
English: These cases have a low incidence and are usually reversible after treatment discontinuation.
Estonian: Need juhud on üldjuhul väga harvad ning pöörduvad pärast ravi lõpetamist.
English: Anti-ischemic effects are achieved without concomitant haemodynamic effects.
Estonian: Anti-isheemiline toime saavutatakse ilma, et samaaegselt esineksid hemodünaamilised toimed.
English: If parkinsonian symptoms persist more than 4 months after drug discontinuation, a neurologist opinion should be sought.
Estonian: Kui parkinsonismi sümptomid kestavad pärast ravimi võtmise lõpetamist kauem kui 4 kuud, tuleb pöörduda neuroloogi poole.
English: In doubtful cases, patients should be referred to a neurologist for appropriate investigations.
Estonian: Kahtluse korral tuleb patsient suunata lisauuringuteks neuroloogile.
English: This includes any side effects not listed in this leaflet.
Estonian: Kõrvaltoime võib olla ka selline, mida selles infolehes ei ole nimetatud
English: Annex III Amendments to relevant sections of the summary of product characteristics and package leaflet
Estonian: III LISA Täiendused ravimi omaduste kokkuvõtte ja pakendi infolehe vastavatesse lõikudesse
English: The majority of the patients recovered within 4 months after trimetazidine withdrawal.
Estonian: Enamikel patsientidest, kes paranesid, kadusid sümptomid 4 kuu jooksul pärast trimetasidiin-ravi katkestamist.
English: A significant difference was also evidenced for the time to onset of angina pectoris (p=0.049).
Estonian: Samuti täheldati olulist erinevust stenokardia tekkimise ajas (p=0,049).
English: - Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Estonian: - Ülitundlikkus toimeaine või lõigus 6.1 loetletud mis tahes abiaine suhtes.
English: Caution should be exercised when prescribing trimetazidine to patients in whom an increased exposure is expected: - moderate renal impairment (see sections 4.2 and 5.2), - elderly patients older than 75 years old (see section 4.2)
Estonian: Ettevaatlik tuleb olla trimetasidiini määramisel patsientidele, kellel võib olla suurenenud trimetasidiini imendumine: - mõõdukas neerukahjustus (vt lõik 4.2 ja 5.2), - üle 75-aastased eakad patsiendid (vt lõik 4.2).
English: No significant difference between groups could be found for the other secondary endpoints (total exercise duration, total workload and clinical endpoints).
Estonian: Erinevates gruppides ei täheldatud olulist erinevust sekundaarsetes tulemusnäitajates (koormustesti kestvus, üldine koormustaluvus, kliinilised näitajad).
English: Dose titration in elderly patients should be exercised with caution (see section 4.4).
Estonian: Annuse tiitrimisel eakatel patsientidel tuleb olla ettevaatlik (vt lõik 4.4).
English: This medicine may make you feel dizzy and drowsy that may affect your ability to drive or use machinery.
Estonian: See ravim võib põhjustada pearinglust või uimasust, mistõttu võib omada toimet teie autojuhtimise või masinate käsitsemise võimele.
English: Trimetazidine can cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia), which should be regularly investigated, especially in elderly patients.
Estonian: Trimetasidiin võib halvendada parkinsonismi sümptomeid (treemor, akineesia, hüpertoonia), mida tuleb regulaarselt uurida, eriti eakatel patsientidel.
English: 5.1 Pharmacodynamic properties [the wording below should be inserted]
Estonian: 5.1 Farmakodünaamilised omadused [lisada tuleb alljärgnev sõnastus]
English: What <invented name>is and what it is used for This medicine is intended for use in adult patient, in combination with other medicines to treat angina pectoris (chest pain caused by coronary disease).
Estonian: Mis ravim on <Väljamõeldud nimetus> ja milleks seda kasutatakse Ravimit kasutatakse täiskasvanutel stenokardia (koronaararteritõvest põhjustatud valu rinnus) raviks kombinatsioonis teiste ravimitega.
English: This medicine can cause or worsen symptoms such as trembling, rigid posture, slow movements and a shuffling, unbalanced walk, especially in elderly patients, which should be investigated and reported to your doctor who could reassess the treatment.
Estonian: See ravim võib põhjustada või halvendada selliseid sümptomeid nagu värisemine, jäik kõnnak, aeglased liigutused ja tõmblused, ebakindel kõnnak, eriti eakatel patsientidel; neid sümptomeid tuleb jälgida ning teavitada nendest oma arsti, kes vajadusel hindab ravi ümber.
English: Falls may occur, related to gait instability or hypotension, in particular in patients taking antihypertensive treatment (see section 4.8).
Estonian: Seoses kõnnakuhäiretega või hüpotensiooniga võib esineda kukkumist, eriti patsientidel, kes saavad antihüpertensiivset ravi (vt lõik 4.8).
English: In an ischaemic cell, energy obtained during glucose oxidation requires less oxygen consumption than in the β-oxidation process.
Estonian: Glükoosi oksüdatsioonil saadud energia isheemilises rakus vajab vähem hapnikku kui β-oksüdatsiooni protsess.
English: Severe reduction in number of white blood cells which makes infections more likely, reduction in blood platelets, which increases risk of bleeding or bruising.
Estonian: Valgete vererakkude hulga raskekujuline vähenemine, mis suurendab infektsioonide tekkeriski, trombotsüütide arvu langus, mis suurendab veritsuste või verevalumite tekkeriski.
English: Arterial Hypotension , Orthostatic hypotension that may be associated with malaise, dizziness or fall, in particular in patients taking antihypertensive treatment, flushing
Estonian: Arteriaalne hüpertensioon, ortostaatiline hüpotensioon, mis võib olla seotud halva enesetundega, pearinglusega või minestamisega, eriti patsientidel, kes saavad antihüpertensiivset ravi, nahaõhetus
English: Blood and lymphatic system disorders
Estonian: Vere ja lümfisüsteemi häired Teadmata
English: Agranulocytosis Thrombocytopenia Thrombocytopenic purpura
Estonian: Agranulotsütoos, Trombotsütopeenia Trombotsütopeeniline purpura
English: 4.1 Therapeutic indications
Estonian: 4.3 Vastunäidustused
English: Sleep disorders (insomnia, drowsiness)
Estonian: Unehäired (unetus, uimasus)
English: In the overall population, including both asymptomatic and symptomatic patients, trimetazidine failed to demonstrate a benefit on both ergometric (total exercise duration, time to onset of 1mm ST and time to onset angina) and clinical endpoints.
Estonian: Üldpopulatsioonis, mis hõlmas nii asümptomaatilisi kui ka sümptomitega patsiente, ei tõestatud trimetasidiini kasulikkust nii ergomeetrilistele (koormustesti kestvus, 1 mm ST-segmendi saabumise aeg, stenokardia saabumise aeg) kui ka kliinilistele tulemusnäitajatele.
English: The dose is one tablet of 35mg of trimetazidine twice daily during meals.
Estonian: Annus on üks 35 mg trimetasidiini tablett 2 korda päevas söögikordade ajal.
English: Clinical studies have demonstrated the efficacy and safety of trimetazidine in the treatment of patients with chronic angina, either alone or when the benefit from other antianginal medicinal products was insufficient.
Estonian: Kliiniliste uuringute käigus on tõestatud trimetasidiini efektiivsust ja ohutust kroonilise stenokardiaga patsientidel nii monoteraapiana või kui teiste stenokardiavastaste ravimite toime oli ebapiisav.
English: Palpitations, extrasystoles, tachycardia
Estonian: Palpitatsioonid, ekstrasüstolid, tahhükardia
English: Potentiation of glucose oxidation optimizes cellular energy processes, thereby maintaining proper energy metabolism during ischaemia.
Estonian: Glükoosi oksüdatsiooni osakaalu suurenemine optimeerib raku energeetilisi protsesse ning säilitab vajalikku energeetilist ainevahetust isheemia korral.
English: Skin and subcutaneous tissue disorders
Estonian: Naha ja nahaaluskoe kahjustused Sage