FrancophonIA/ELRC3.0 huggingface dataset:
English: If you are already taking a nonsteroidal anti-inflammatory drug (NSAID) and/or corticosteroids, you may continue to take them after starting Leflunomide ratiopharm.
Croatian: Ako već uzimate nesteroidne protuupalne lijekove (NSAIL) i/ili kortikosteroide, možete ih nastaviti uzimati nakon što počnete uzimati Leflunomid ratiopharm.
English: Studies with both hemodialysis and CAPD (chronic ambulatory peritoneal dialysis) indicate that A771726, the primary metabolite of leflunomide, is not dialysable
Croatian: Studije s hemodijalizom i kroničnom ambulantnom peritonealnom dijalizom upućuju da se A771726, primarni metabolit leflunomida, ne može dijalizirati.
English: The pharmacokinetics of A771726 following oral administration of leflunomide have been investigated in 73 pediatric patients with polyarticular course Juvenile Rheumatoid Arthritis (JRA) who ranged in age from 3 to 17 years.
Croatian: Farmakokinetika A771726 nakon peroralne primjene leflunomida ispitivana je u 73 pedijatrijska bolesnika u dobi od 3 do 17 godina s poliartikuliranim oblikom juvenilnog reumatoidnog artritisa (JRA).
English: Moreover, switching from leflunomide to another DMARD without following the washout procedure (see section 4.4) may also increase the risk of serious adverse reactions even for a long time after the switching.
Croatian: Osim toga, prijelaz s leflunomida na neki drugi DMARD, bez provedbe postupka ispiranja (engl. „washout“) leflunomida (vidjeti dio 4.4.), također može povećati rizik od ozbiljnih nuspojava, čak i dulje vrijeme nakon promjene lijeka.
English: • Patients with significantly impaired bone marrow function or significant anaemia, leucopenia, neutropenia or thrombocytopenia due to causes other than rheumatoid or psoriatic arthritis,
Croatian: • Bolesnici sa značajno oštećenom funkcijom koštane srži ili izraženom anemijom, leukopenijom, neutropenijom ili trombocitopenijom, koje nisu uzrokovane reumatoidnim ili psorijatičnim artritisom
English: If you forget to take Leflunomide ratiopharm
Croatian: Ako ste zaboravili uzeti Leflunomid ratiopharm
English: White to almost white, round film-coated tablet with a diameter of about 6 mm.
Croatian: Bijela do gotovo bijela okrugla, filmom obložena tableta promjera oko 6 mm.
English: - The other ingredients are lactose monohydrate, low-substituted hydroxypropyl cellulose, tartaric acid, sodium laurylsulfate and magnesium stearate in the tablet core as well as lecithin (soybeans), poly(vinyl alcohol), talc, titanium dioxide (E171) and xanthan gum in the film-coating
Croatian: - Drugi sastojci su laktoza hidrat, niskosupstituirana hidroksipropilceluloza, tartaratna kiselina, natrijev laurilsulfat i magnezijev stearat u jezgri tablete, kao i lecitin (zrna soje), poli(vinilni alkohol), talk, titanijev dioksid (E171) i ksantanska guma u film-ovojnici.
English: In the phase III trials, the ACR response rates for leflunomide 20 mg/day versus placebo were 54.6% vs. 28.6% (study MN301), and 49.4% vs. 26.3% (study US301).After 12 months with active treatment, the ACR response rates in leflunomide patients were 52.3% (studies MN301/303), 50.5% (study MN302) and 49.4% (study US301), compared to 53.8% (studies MN301/303) in sulphasalazine patients, 64.8% (study MN302), and 43.9% (study US301) in methotrexate patients.
Croatian: Nakon 12 mjeseci aktivnog liječenja stopa odgovora prema ACR-u u bolesnika koji su primali leflunomid bila je 52,3% (studije MN301/303), 50,5% (studija MN302) i 49,4% (studija US301) u usporedbi s 53,8% (studije MN301/303) u bolesnika koji su primali sulfasalazin te 64,8% (studija MN302) i 43,9% (studija US301) u bolesnika koji su primali metotreksat.
English: The patient must be advised that if there is any delay in onset of menses or any other reason to suspect pregnancy, they must notify the physician immediately for pregnancy testing, and if positive, the physician and patient must discuss the risk to the pregnancy.
Croatian: Bolesnice treba savjetovati da u slučaju kašnjenja menstruacije ili sumnje na trudnoću odmah moraju obavijestiti liječnika zbog provođenja testa na trudnoću.
English: toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme
Croatian: Vrlo rijetko: toksična epidermalna nekroliza, Stevens-Johnsonov sindrom, multiformni eritem
English: Your doctor will carry out blood tests at regular intervals, before and during treatment with Leflunomide ratiopharm, to monitor your blood cells and liver.
Croatian: Prije i za vrijeme liječenja Leflunomid ratiopharmm liječnik će Vas u redovitim razmacima slati na krvne pretrage zbog kontrole Vaših krvnih stanica i jetre.
English: A771726 plasma levels can be expected to be above 0.02 mg/L for a prolonged period.
Croatian: Očekuje se da će se koncentracija A771726 u plazmi, viša od 0,02 mg/l, zadržati duže vrijeme.
English: Each film-coated tablet contains 76 mg of lactose and 0.06 mg of soya lecithin.
Croatian: Jedna filmom obložena tableta sadrži 76 mg laktoze i 0,06 mg sojinog lecitina.
English: Leflunomide ratiopharm contains the active substance leflunomide which belongs to a group of medicines called anti-rheumatic medicines.
Croatian: Leflunomid ratiopharm sadrži djelatnu tvar leflunomid koja pripada skupini antireumatskih lijekova.
English: Tell your doctor immediately if you experience: - pale skin, tiredness, or bruising, as these may indicate blood disorders caused by an imbalance in the different types of blood cells which make up blood, - tiredness, abdominal pain, or jaundice (yellow discolouration of the eyes or skin), as these may indicate serious conditions such as liver failure, which may be fatal, - any symptoms of an infection such as fever, sore throat or cough, as this medicine may increase the chance of a severe infection which may be life-threatening, - cough or breathing problems as these may indicate problems of the lung (interstitial lung disease or pulmonary hypertension), - unusual tingling, weakness or pain in your hands or feet as these may indicate problems with your nerves (peripheral neuropathy).
Croatian: Odmah obavijestite svog liječnika u slučaju: - bljedoće kože, umora ili pojave modrica jer to može upućivati na krvne poremećaje uzrokovane poremećenom ravnotežom različitih vrsta krvnih stanica, - umora, boli u trbuhu ili žutice (žuta boja bjeloočnica ili kože) jer to može upućivati na teška stanja kao što je zatajenje jetre, koje može dovesti do smrtnog ishoda, - bilo kojeg simptoma infekcije kao što su vrućica, grlobolja ili kašalj jer ovaj lijek može povećati rizik od teških infekcija koje mogu biti opasne po život. - kašlja ili problema s disanjem budući da ovi problemi mogu ukazivati na probleme s plućima (intersticijska bolest pluća ili plućna hipertenzija) - neuobičajenih trnaca, slabosti li bolova u šakama ili stopalima jer mogu upućivati na probleme sa živcima (periferna neuropatija).
English: What Leflunomide ratiopharm is and what it is used for What you need to know before you take Leflunomide ratiopharm How to take Leflunomide ratiopharm Possible side effects
Croatian: Što Leflunomid ratiopharm i za što se koristi Što morate znati prije nego počnete uzimati Leflunomid ratiopharm
English: Other side effects such as kidney failure, a decrease in the levels of uric acid in your blood, pulmonary hypertension, male infertility (which is reversible once treatment with this medicine is stopped), cutaneous lupus (characterized by rash/erythema on skin areas that are exposed to light), psoriasis (new or worsening) and DRESS may also occur with a not known frequency.
Croatian: Druge nuspojave kao što su zatajenje bubrega, pad razine mokraćne kiseline u krvi, plućne hipertenzije, muška neplodnost (koja je reverzibilna nakon prestanka liječenja ovim lijekom), kožni lupus (karakteriziran osipom/crvenilom na područjima kože izloženima svjetlu), psorijaza (novonastala psorijaza ili pogoršanje psorijaze) i reakcije na lijek s eozinofilijom i sistemskim simptomima (DRESS) također se mogu javiti, a njihova učestalost nije poznata.
English: Tell your doctor immediately and stop taking Leflunomide ratiopharm: if you experience weakness, feel light-headed or dizzy or have difficulty breathing, as these may be signs of a serious allergic reaction, if you develop a skin rash or ulcers in your mouth, as these may indicate severe, sometimes life-threatening reactions (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, Drug Reaction with Eosinophilia and Systemic Symptoms [DRESS]), see section 2.
Croatian: Odmah obavijestite svog liječnika i prestanite uzimati Leflunomid ratiopharm: - ako osjetite slabost, ošamućenost ili omaglicu ili imate poteškoće s disanjem jer to mogu biti znaci ozbiljne alergijske reakcije, - ako dobijete kožni osip ili čireve u ustima jer to može upućivati na teške reakcije, ponekad opasne po život (npr. Stevens-Johnsonov sindrom, toksična epidermalna nekroliza, multiformni eritem, reakcija na lijek s eozinofilijom i sistemskim simptomima, engl.
English: Each film-coated tablet contains 152 mg of lactose and 0.12 mg of soya lecithin.
Croatian: Jedna filmom obložena tableta sadrži 152 mg laktoze i 0,12 mg sojinog lecitina.
English: Repeated doses of A771726 decreased mean Cmax and AUC of caffeine (CYP1A2 substrate) by 18% and 55%, respectively, suggesting that A771726 may be a weak inducer of CYP1A2 in vivo.
Croatian: Ponovljene doze A771726 smanjile su prosječnu Cmax i AUC kofeina (CYP1A2 supstrat) za 18%, odnosno za 55%, što ukazuje na to da bi A771726 mogao biti slabi induktor CYP1A2 in vivo.
English: Talk to your doctor, pharmacist or nurse before taking Leflunomide ratiopharm - if you have ever suffered from interstitial lung disease.
Croatian: Upozorenja i mjere opreza Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego uzmete Leflunomid ratiopharm - ako ste ikad imali intersticijsku plućnu bolest.
English: Leflunomide ratiopharm 20 mg
Croatian: Leflunomid ratiopharm 20 mg
English: Leflunomide ratiopharm 10 mg
Croatian: Leflunomid ratiopharm 10 mg
English: If a waiting period of up to approximately 2 years under reliable contraception is considered unpractical, prophylactic institution of a washout procedure may be advisable.
Croatian: Ako nije moguće čekati dvije godine uz odgovarajuću kontracepciju, preporučuje se profilaktički započeti ispiranje (engl. "washout").
English: Titanium dioxide (E171) Xanthan gum
Croatian: Film-ovojnica lecitin (zrna soje) poli(vinilni) alkohol talk titanijev dioksid (E171) ksantanska guma
English: There was an increase in mean rosuvastatin Cmax and AUC (2.65- and 2.51-fold, respectively), following repeated doses of A771726.
Croatian: Zabilježeno je povećanje prosječne Cmax i AUC (2,65 odnosno 2,51 puta) za rosuvastatin nakon ponovljenih doza A771726.
English: At a dose level of 20 mg/day, average plasma concentration of A771726 at steady state is approximately
Croatian: Pri dozi od 20 mg/dan prosječna koncentracija A771726 u plazmi u stanju dinamičke ravnoteže iznosila je oko 35 μg/ml.
English: Marketing Authorisation Holder ratiopharm GmbH Graf-Arco-Straße 3 89079 Ulm Germany
Croatian: Nositelj odobrenja za stavljanje gotovog lijeka u promet ratiopharm GmbH Graf-Arco-Straße 3 89079 Ulm Njemačka
English: Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1.43- and 1.54-fold, respectively), following repeated doses of A771726, suggesting that A771726 is an inhibitor of OAT3 in vivo.
Croatian: Učinak na supstrate organskog anionskog transportera 3 (OAT3) Zabilježeno je povećanje prosječne Cmax i AUC (1,43 odnosno 1,54 puta) za cefaklor, nakon ponovljenih doza A771726, što ukazuje na to da je A771726 inhibitor OAT3 in vivo.
English: EU/1/10/654/003 EU/1/10/654/004
Croatian: EU/1/10/654/004
English: Other medicines and Leflunomide ratiopharm
Croatian: Drugi lijekovi i Leflunomid ratiopharm
English: Your doctor may perform tests to see if you have tuberculosis.
Croatian: Vaš liječnik može provesti testove kako bi ustanovio imate li tuberkulozu. - ako morate napraviti određenu krvnu pretragu (utvrđivanje razine kalcija).
English: The efficacy of leflunomide was demonstrated in one controlled, randomised, double blind study 3L01 in 188 patients with psoriatic arthritis, treated at 20 mg/day.
Croatian: Djelotvornost leflunomida u liječenju psorijatičnog artritisa pokazala se u jednom kontroliranom, randomiziranom, dvostruko slijepom ispitivanju 3L01 na 188 bolesnika s psorijatičnim artritisom.
English: Leflunomide ratiopharm contains lactose.
Croatian: Leflunomid ratiopharm sadrži laktozu.
English: The most frequently reported adverse effects with leflunomide are: mild increase in blood pressure, leucopenia, paraesthesia, headache, dizziness, diarrhoea, nausea, vomiting, oral mucosal disorders (e.g. aphthous stomatitis, mouth ulceration), abdominal pain, increased hair loss, eczema, rash (including maculo-papular rash), pruritus, dry skin, tenosynovitis, CPK increased, anorexia, weight loss (usually insignificant), asthenia, mild allergic reactions and elevation of liver parameters (transaminases (especially ALT), less often gamma-GT, alkaline phosphatise, bilirubin).
Croatian: Najčešće zabilježene nuspojave tijekom primjene leflunomida su: blagi porast krvnog tlaka, leukopenija, parestezija, glavobolja, omaglica, proljev, mučnina, povraćanje, poremećaji sluznice usne šupljine (npr. aftozni stomatitis, ulceracije u ustima), bol u trbuhu, pojačani gubitak kose, ekcem, osip (uključujući makulopapulozni osip), svrbež, suha koža, tenosinovitis, povećanje CPK, anoreksija, gubitak težine (obično beznačajan), astenija, blage alergijske reakcije i porast jetrenih parametara (transaminaze (osobito ALT), manje često gama-GT, alkalna fosfataza, bilirubin).
English: There was an increase in mean repaglinide Cmax and AUC (1.7- and 2.4-fold, respectively), following repeated doses of A771726, suggesting that A771726 is an inhibitor of CYP2C8 in vivo.
Croatian: Zabilježeno je povećanje prosječne Cmax i AUC (1,7 odnosno 2,4 puta) za repaglinid, nakon ponovljenih doza A771726, što ukazuje na to da je A771726 inhibitor CYP2C8 in vivo.
English: Leflunomide ratiopharm with food, drink and alcohol
Croatian: Leflunomid ratiopharm s hranom, pićem i alkoholom Leflunomid ratiopharm se može uzeti s hranom ili bez nje.
English: Leflunomide ratiopharm contains soya lecithin
Croatian: Leflunomid ratiopharm sadrži sojin lecitin
English: A randomised, double-blind, parallel-group non-inferiority study compared the relative efficacy of two different daily maintenance doses of leflunomide, 10 mg and 20 mg. From the results it can be concluded that efficacy results of the 20 mg maintenance dose were more favourable, on the other hand, the safety results favoured the 10 mg daily maintenance dose.
Croatian: Randomiziranom, dvostruko slijepom, neinferiornom studijom paralelnih grupa uspoređivala se relativna djelotvornost dviju različitih dnevnih doza održavanja leflunomida, odnosno 10 i 20 mg.
English: Lactose monohydrate Low-substituted hydroxypropyl cellulose Tartaric acid
Croatian: Jezgra tablete laktoza hidrat hidroksipropilceluloza, niskosupstituirana tartaratna kiselina natrijev laurilsulfat magnezijev stearat
English: All elevations resolved, 2 with continuation of both medicinal products and 3 after discontinuation of leflunomide.
Croatian: Sve su se povišene vrijednosti smanjile u 2 bolesnika koji su nastavili istodobno uzimati oba lijeka i u 3 bolesnika koji su prekinuli uzimati leflunomid.
English: EU/1/10/654/003 30 film-coated tablets EU/1/10/654/004 100 film-coated tablets
Croatian: EU/1/10/654/003 30 filmom obloženih tableta EU/1/10/654/004 100 filmom obloženih tableta
English: White to almost white, round film-coated tablet with a diameter of 8 mm and a break-mark on one side of the tablet.
Croatian: Bijela do gotovo bijela, okrugla filmom obložena tableta promjera 8 mm, s razdjelnom crtom na jednoj strani tablete, Tableta se može razdijeliti na jednake polovice.
English: other medicines for rheumatoid arthritis such as antimalarials (e.g. chloroquine and hydroxychloroquine), intramuscular or oral gold, D-penicillamine, azathioprine and other immunosuppressive medicines (e.g. methotrexate) as these combinations are not advisable, - warfarin and other oral medicines used to thin the blood, as monitoring is necessary to reduce the risk of side effects of this medicine - teriflunomide for multiple sclerosis - repaglinide, pioglitazone, nateglinide, or rosiglitazone for diabetes - daunorubicin, doxorubicin, paclitaxel, or topotecan for cancer - duloxetine for depression, urinary incontinence or in kidney disease in diabetics - alosetron for the management of severe diarrhoea - theophylline for asthma - tizanidine, a muscle relaxant - oral contraceptives (containing ethinylestradiol and levonorgestrel) - cefaclor, benzylpenicillin (penicillin G), ciprofloxacin for infections - indomethacin, ketoprofen for pain or inflammation - furosemide for heart disease (diuretic, water pill) - zidovudine for HIV infection
Croatian: metotreksat) jer se ne savjetuje primjena tih kombinacija. - varfarin i druge oralne lijekove koji se koriste za razrjeđivanje krvi, jer je potrebno praćenje kako bi se smanjio rizik od nuspojava tih lijekova - teriflunomid za liječenje multiple skleroze - repaglinid, pioglitazon, nateglinid ili roziglitazon za liječenje šećerne bolesti - daunorubicin, doksorubicin, paklitaksel ili topotekan za liječenje raka - duloksetin za liječenje depresije, nesposobnosti zadržavanja mokraće ili bolesti bubrega u oboljelih od šećerne bolesti - alosetron za liječenje teškog proljeva - teofilin za liječenje astme - tizanidin, lijek za opuštanje mišića - oralni kontraceptivi (koji sadrže etinilestradiol i levonorgestrel) - cefaklor, benzilpenicilin (penicilin G), ciprofloksacin, za liječenje infekcija - indometacin, ketoprofen za liječenje boli ili upale - furosemid za liječenje bolesti srca (diuretik, tableta za vodu)
English: EU/1/10/654/001 30 film-coated tablets EU/1/10/654/002 100 film-coated tablets
Croatian: EU/1/10/654/001 30 filmom obloženih tableta EU/1/10/654/002 100 filmom obloženih tableta
English: All of these also resolved, 2 with continuation of both medicinal products and 3 after discontinuation of leflunomide.
Croatian: Sve su se te vrijednosti smanjile u 2 bolesnika koji su nastavili istodobno uzimati oba lijeka i u 3 bolesnika koji su prekinuli uzimati leflunomid.
English: - diarrhoea, - colitis, - nausea, vomiting, - inflammation of the mouth or mouth ulcers, - abdominal pain, - an increase in some liver test results, - increased hair loss, - eczema, dry skin, rash, itching, - tendonitis (pain caused by inflammation in the membrane surrounding the tendons usually in the feet or hands), - an increase of certain enzymes in the blood (creatine phosphokinase), - problems in the nerves of the arms or legs (peripheral neuropathy).
Croatian: - abnormalne kožne reakcije kao trnci (parestezije), - blaži porast krvnog tlaka, - proljev, - kolitis, - mučnina, povraćanje, - upala u ustima ili čirevi u ustima, - bol u trbuhu, - porast vrijednosti određenih jetrenih enzima, - pojačan gubitak kose, - ekcem, suha koža, osip, svrbež, - tendinitis (bol uzrokovana upalom membrana koje okružuju tetive obično na stopalima ili rukama), - porast koncentracije određenih enzima u krvi (kreatin fosfokinaze), - problemi sa živcima u rukama ili nogama (periferna neuropatija).
English: Leflunomide ratiopharm 10 mg film-coated tablets are white to almost white and round with a diameter of about 6 mm.
Croatian: Kako Leflunomid ratiopharm izgleda i sadržaj pakiranja Leflunomid ratiopharm 10 mg filmom obložene tablete su bijele do gotovo bijele i okrugle, promjera oko 6 mm.
English: Leflunomide ratiopharm 20 mg film-coated tablets are white to almost white and round with a diameter of about 8 mm and a break-mark on one side of the tablet.
Croatian: Kako Leflunomid ratiopharm izgleda i sadržaj pakiranja Leflunomid ratiopharm 20 mg filmom obložene tablete su bijele do gotovo bijele i okrugle, promjera 8 mm, s razdjelnom crtom na jednoj strani tablete.
English: anaemia, mild thrombocytopenia (platelets <100 G/L)
Croatian: Manje često: anemija, blaga trombocitopenija (trombociti <100 g/l).
English: Drinking alcohol while taking Leflunomide ratiopharm may increase the chance of liver damage.
Croatian: Za vrijeme liječenja Leflunomidom ratiopharm ne preporučuje se konzumacija alkohola.Uzimanje alkohola za vrijeme liječenja Leflunomidom ratiopharm može povećati mogućnost oštećenja jetre.
English: The concentration may be expected to decrease below 0.02 mg/L about 2 years after stopping the treatment with leflunomide.
Croatian: Smanjenje koncentracije A771726 u plazmi na razinu nižu od 0,02 mg/l očekuje se za oko dvije godine nakon prekida liječenja leflunomidom.
English: Tel: +39 02 891 798 1
Croatian: Teva Italia S.r.l. Tel: +39 02 891 798 1
English: What you need to know before you take Leflunomide ratiopharm Do not take Leflunomide ratiopharm if you have ever had an allergic reaction to leflunomide (especially a serious skin reaction, often accompanied by fever, joint pain, red skin stains, or blisters e.g. Stevens-Johnson syndrome), to peanut or soya or to any of the other ingredients of this medicine (listed in section if you have any liver problems, if you have moderate to severe kidney problems, if you have severely low numbers of proteins in your blood (hypoproteinaemia), if you suffer from any problem which affects your immune system (e.g. AIDS), if you have any problem with your bone marrow, or if you have low numbers of red or white cells in your blood or a reduced number of blood platelets, if you are suffering from a serious infection, if you are pregnant, think you may be pregnant, or are breast-feeding.
Croatian: npr. Steven-Johnsonov sindrom), na kikiriki ili soju ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.), - ako imate probleme s jetrom, - ako imate umjerene do teške probleme s bubrezima, - ako imate izrazito niske vrijednosti proteina u krvi (hipoproteinemija), - ako bolujete od bilo koje bolesti koja utječe na Vaš imunološki sustav (npr. AIDS), - ako imate bilo kakvih problema s koštanom srži ili ako imate smanjen broj crvenih ili bijelih krvnih stanica ili krvnih pločica (trombocita), - ako imate jaku infekciju, - ako ste trudni, mislite da biste mogli biti trudni ili dojite.
English: Teva Nederland B.V. Tel: +31 (0) 800 0228 400
Croatian: Tel: +31 (0)800 0228 400
English: Film-coated tablet 30 film-coated tablets 100 film-coated tablets
Croatian: OBLIK I SADRŽAJ Filmom obložena tableta 30 filmom obloženih tableta 100 filmom obloženih tableta NAČIN I PUT(EVI) PRIMJENE LIJEKA Kroz usta.
English: Certain vaccinations should not be given while taking Leflunomide ratiopharm, and for a certain amount of time after stopping treatment.
Croatian: Za vrijeme uzimanja Leflunomida ratiopharm kao i određeno vrijeme nakon prekida liječenja ne smije se provoditi cijepljenje određenim cjepivima.
English: a decrease in the number of red blood cells (anaemia) and a decrease in the number of blood platelets (thrombocytopenia), - a decrease in the levels of potassium in the blood, - anxiety, - taste disturbances, - urticaria (nettle rash), - tendon rupture, - an increase in the levels of fat in the blood (cholesterol and triglycerides), - a decrease in the levels of phosphate in the blood.
Croatian: (trombocitopenija), - smanjenje koncentracije kalija u krvi, - tjeskoba, - poremećaji okusa, - koprivnjača (urtikarija), - ruptura tetiva, - povećanje razine masnoća u krvi (kolesterol i trigliceridi), - smanjenje razine fosfata u krvi.
English: The long half-life of leflunomide should be considered when contemplating administration of a live attenuated vaccine after stopping Leflunomide ratiopharm.
Croatian: Kad se razmatra primjena živih atenuiranih cjepiva nakon prekida liječenja lijekom Leflunomid ratiopharm, potrebno je uzeti u obzir dugi poluvijek leflunomida.
English: One film-coated tablet contains 20 mg of leflunomide.
Croatian: Jedna filmom obložena tableta sadrži 20 mg leflunomida.
English: Leflunomide ratiopharm is for oral use.
Croatian: Leflunomid ratiopharm je za peroralnu primjenu.