FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients should be advised that treatment with Telzir, or any other current antiretroviral therapy, does not cure HIV and that they may still develop opportunistic infections and other complications of HIV infection.
Danish: Patienter bør orienteres om, at Telzir eller enhver anden nuværende antiretroviral behandling ikke kurerer hiv.
English: Norethisterone: AUC
Danish: Etravirin AUC 
English: No dosage adjustment of fosamprenavir or dolutegravir is recommended based on observed exposureresponse relationships of clinical data.
Danish: Baseret på de observerede eksponerings-responssammenhænge fra kliniske data anbefales dosisjustering af fosamprenavir eller dolutegravir ikke.
English: How to take Telzir
Danish: Sådan skal du tage Telzir
English: - alfuzosin (used to treat a prostate problem) - astemizole or terfenadine (commonly used to treat allergy symptoms - these medicines may be available without prescription) - pimozide (used to treat schizophrenia) - quetiapine (used to treat schizophrenia, bipolar disorder and major depressive disorder) - lurasidone (used to treat schizophrenia and bipolar disorder) - cisapride (used to relieve indigestion) - ergot derivatives (used to treat headaches) - rifampicin (used to treat tuberculosis) - amiodarone, quinidine, flecainide and propafenone (heart medicines) - bepridil (used to treat high blood pressure) - oral midazolam or oral triazolam (used to treat anxiety) - products containing St John's wort (Hypericum perforatum) - lovastatin, simvastatin (used to lower cholesterol) - sildenafil if used to treat pulmonary arterial hypertension, (a condition affecting the blood vessels to your lungs) - paritaprevir (used to treat hepatitis C virus infection)
Danish: pimozid (til behandling af skizofreni) quetiapin (til behandling af skizofreni, bipolar (manio-depressiv) lidelse og svær depressiv sygdom) lurasidon (til behandling af skizofreni og bipolar (manio-depressiv) lidelse cisaprid (til behandling af fordøjelsesbesvær) sekalealkaloider (til behandling af migræne) rifampicin (til behandling af tuberkulose) amiodaron, quinidin, flecainid og propafenon (hjertemedicin) bepridil (til behandling af forhøjet blodtryk) oral midazolam eller oral triazolam (til behandling af angst) naturlægemidler, der indeholder perikon (hypericum perforatum) lovastatin, simvastatin (til behandling af forhøjet kolesterol i blodet) sildenafil, hvis det bliver anvendt til behandling af pulmonal arteriel hypertension (en sygdom, der påvirker blodkarrene til lungerne) paritaprevir (til behandling af hepatitis C-virusinfektion).
English: • injectable midazolam (used to treat anxiety)
Danish: • midazolam som injektion (mod angst)
English: PHARMACEUTICAL FORM Oral suspension
Danish: Oral suspension
English: It is bound to the alpha-1acid glycoprotein (AAG) and albumin,but has a higher affinity for AAG.
Danish: Amprenavir bindes hovedsageligt til alfa-1-syre glycoprotein (AAG), men også til albumin.
English: The median durations of prior exposure to NRTIs were 257 weeks for patients receiving fosamprenavir with ritonavir twice daily (79 % had ≥ 3 prior NRTIs) and 210 weeks for patients receiving lopinavir/ritonavir (64 % had ≥ 3 prior NRTIs).
Danish: Varigheden (median) af tidligere behandling med NRTI'er var 257 uger for patienter, som fik fosamprenavir og ritonavir 2 gange daglig (79 % havde tidligere fået  3 NRTI'er), og 210 uger for patienter, som fik lopinavir/ritonavir (64 % havde tidligere fået  3 NRTI'er).
English: The full prescribing information for ritonavir must therefore be consulted prior to initiation of therapy with Telzir with ritonavir.
Danish: Den fulde produktinformation for ritonavir skal derfor læses før påbegyndelse af kombinationsbehandling med Telzir og ritonavir.
English: What Telzir looks like and contents of the pack Telzir is supplied in plastic bottles containing 60 film-coated tablets.
Danish: Telzir findes i plastbeholdere med 60 filmovertrukne tabletter.
English: Amprenavir: Cmax ↔* Amprenavir: AUC ↔* Amprenavir: Cmin ↔* * compared to historical data
Danish: Amprenavir: Cmax * Amprenavir: AUC * Amprenavir: Cmin * * sammenlignet med historiske data
English: The pharmacokinetic properties of amprenavir following co-administration of Telzir with ritonavir have been evaluated in healthy adult subjects and HIV-infected patients and no substantial differences were observed between these two groups.
Danish: Amprenavirs farmakokinetiske egenskaber efter samtidig administration af Telzir og ritonavir er undersøgt hos raske voksne forsøgspersoner og hos hiv-inficerede patienter.
English: Telzir oral suspension is the recommended option for the most accurate dosing in children based on body weight.
Danish: Børn bør anvende Telzir oral suspension, idet den nøjagtige dosering til denne patientgruppe baseres på kropsvægt.
English: The benefit in this age group has mainly been derived from study APV29005, an open label 48 week study evaluating the pharmacokinetic profiles, safety, and antiviral activity of fosamprenavir with ritonavir administered twice daily to HIV 1 protease inhibitor experienced and naive patients 2 to 18 years of age.
Danish: APV29005 var et åbent, 48 ugers studie, som evaluerede den farmakokinetiske profil, sikkerheden og den antivirale aktivitet af fosamprenavir i kombination med ritonavir administreret 2 gange daglig hos hiv-1-positive patienter mellem 2 og 18 år.
English: • raltegravir (used to treat HIV infection)
Danish: • raltegravir (mod hiv-infektion)
English: The recommended dose is 14 ml Telzir oral suspension (700 mg fosamprenavir) twice daily with 100 mg ritonavir (as capsule or oral solution) twice daily.
Danish: Den sædvanlige dosis er 14 ml Telzir oral suspension (700 mg fosamprenavir) 2 gange daglig sammen med 100 mg ritonavir (som kapsel eller oral opløsning) 2 gange daglig.
English: The apparent volume of distribution of amprenavir following administration of Telzir is approximately 430 l (6 l/kg assuming a 70 kg body weight), suggesting a large volume of distribution, with penetration of amprenavir freely into tissues beyond the systemic circulation.
Danish: Fordelingsvolumenet af amprenavir efter administration af Telzir er ca. 430 l (6 1/kg ved en kropsvægt på 70 kg).
English: Oral suspension should be taken with food 25-32 kg Oral suspension
Danish: 25-32 kg Oral suspension
English: 20 mg once daily
Danish: 20 mg én gang daglig
English: Sixteen of 434 ART-naïve patients who received fosamprenavir 700 mg/ritonavir 100 mg twice daily in ESS100732 experienced virological failure by Week 48 with 14 isolates genotyped.
Danish: I studiet ESS100732 fik 16 ud af 434 ART-naive patienter, der blev behandlet med 700 mg fosamprenavir/100 mg ritonavir 2 gange daglig, virologisk svigt efter 48 ugers behandling.
English: These may affect up to 1 in 10 people:
Danish: Almindelige bivirkninger (kan forekomme hos op til 1 ud af 10 personer):
English: Administration of fosamprenavir 700 mg twice daily with ritonavir 100 mg twice daily results in plasma amprenavir concentrations (data from study APV30003 in antiretroviral experienced patients) which results in protein adjusted median ratios of Cmin/IC50 and Cmin/IC95 of 21.7 (range 1.19-240) and 3.21 (range 0.26-30.0), respectively.
Danish: Administration af 700 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir 2 gange daglig resulterer i plasmakoncentrationer af amprenavir med proteinjusterede mediane ratioer for Cmin/IC50 og Cmin/IC95 på henholdsvis 21,7 (interval 1,19-240) og 3,21 (interval 0,26-30,0) (data fra studie APV30003 af patienter, der tidligere er behandlet med antiretrovirale midler).
English: In animal studies at systemic plasma exposures (AUC) to amprenavir lower than therapeutic exposure in patients treated with Telzir, some developmental toxicity was observed (see section 5.3).
Danish: I dyrestudier blev der observeret tegn på udviklingstoksicitet ved systemiske amprenavirplasmaniveauer (AUC), som var lavere end det terapeutiske niveau hos patienter, som behandles med Telzir (se pkt.
English: After multiple dose oral administration of fosamprenavir 700 mg with ritonavir 100 mg twice daily, amprenavir was rapidly absorbed with a geometric mean (95 % CI) steady state peak plasma amprenavir concentration (Cmax) of 6.08 (5.38-6.86) µg/ml occurring approximately 1.5 (0.75-5.0) hours after dosing (tmax).
Danish: Ved gentagen oral dosering af 700 mg fosamprenavir og 100 mg ritonavir 2 gange daglig blev amprenavir hurtigt absorberet med en maksimal steady state amprenavir-plasmakoncentration (Cmax) på 6,08 (5,38-6,86) g/ml (geometrisk gennemsnit (95 % CI)) ca. 1,5 (0,75-5,0) timer efter dosering (tmax).
English: CSF penetration of amprenavir is negligible in humans.
Danish: Amprenavirs distribution til cerebrospinalvæsken er ubetydelig hos mennesker.
English: Baseline HIV-1 RNA ≥ 100,000 copies/ml
Danish: Baseline-hiv-1-RNA ≥ 100.000 kopier/ml
English: magnesium stearate, colloidal anhydrous silica, hypromellose, titanium dioxide (E171), glycerol triacetate, iron oxide red (E172).
Danish: • Øvrige indholdsstoffer: mikrokrystallinsk cellulose, croscarmellosenatrium, povidon K30, magnesiumstearat, kolloid vandfri silica, hypromellose, titandioxid (E171), glyceroltriacetat, rød jernoxid (E172).
English: Fosamprenavir with ritonavir therapy should be definitively stopped in case of severe rash or in case of rash of mild or moderate intensity associated with systemic or mucosal signs (see section 4.4).
Danish: Fosamprenavir og ritonavir bør seponeres permanent i tilfælde af alvorlige udslæt, eller i tilfælde af milde eller moderate udslæt ledsaget af systemiske eller mucosale symptomer (se pkt.
English: ORAL ANTICOAGULANTS
Danish: ORALE ANTIKOAGULANTIA
English: Results from studies with other HIV protease inhibitors and simeprevir or daclatasvir, suggest that coadministration with fosamprenavir/ritonavir is likely to lead to increased plasma exposures of simeprevir or daclatasvir due to CYP3A4 enzyme inhibition.
Danish: Resultater fra studier med andre hiv-proteasehæmmere og simeprevir eller daclatasvir antyder, at administration sammen med fosamprenavir/ritonavir sandsynligvis medfører øget plasmaniveau af simeprevir og daclatasvir pga. CYP3A4enzymhæmning.
English: AUC ↓ 16% (-36%; +8%) Cmin ↓ 19% (-42%; +13%)
Danish: Cmax 14 % (-36 % til +15 %) AUC 16 % (-36 % til +8 %) Cmin 19 % (-42 % til +13 %)
English: The adult dose of Telzir tablet 700 mg twice daily with ritonavir 100 mg twice daily may be used in children weighing at least 39 kg and able to swallow tablets.
Danish: Den voksne dosering, en Telzir tablet på 700 mg i kombination med 100 mg ritonavir 2 gange daglig, kan anvendes til børn, hvis de vejer mindst 39 kg og kan sluge tabletter.
English: Median CD4 cells/μl CD4 count < 350 cells/μl, n (%)
Danish: > 100,000 kopier/ml, n (%) median CD4 celler/μl CD4-tal < 350 celler/μl, n (%) Effektresultat
English: FPV/RTV BID (N=107)
Danish: FPV/RTV 2 gange daglig (n=107)
English: Norethisterone: Cmax
Danish: Etravirin Cmax 
English: Results from studies with 4.3).
Danish: 4.3 og 4.5).
English: • If you have a known allergy to medicines containing sulphonamide.
Danish: • hvis du er allergisk over for medicin, der indeholder sulfonamid, da du så også kan være allergisk over for Telzir
English: The inducing effect may persist for at least 2 weeks after cessation of treatment with St John's wort.
Danish: Den induktive effekt kan vare i op til 2 uger efter seponering af perikon.
English: Turn the bottle upside down.
Danish: Vend flasken på hovedet.
English: Telzir must only be given with low dose ritonavir as a pharmacokinetic enhancer of amprenavir and in combination with other antiretroviral medicinal products.
Danish: Telzir må kun administreres i kombination med en lav dosis ritonavir og i kombination med andre antiretrovirale lægemidler.
English: INFECTION Antibacterials:
Danish: Antibiotika:
English: The median durations of prior exposure to protease inhibitors were 149 weeks for patients receiving fosamprenavir with ritonavir twice daily (49 % received ≥ 2 prior PIs) and 130 weeks for patients receiving lopinavir/ritonavir (40 % received ≥2 prior PIs).
Danish: Varigheden (median) af sidste behandling med proteasehæmmere var 149 uger for patienter, som fik fosamprenavir og ritonavir 2 gange daglig (49 % havde tidligere fået  2 PI'er), og 130 uger for patienter, som fik lopinavir/ritonavir (40 % havde tidligere fået  2 PI'er).
English: Rat pups exposed pre and post-natally to amprenavir and fosamprenavir showed developmental toxicity (see section 5.3).
Danish: Hos rotteunger, der før og efter fødslen har været eksponeret for amprenavir og fosamprenavir, blev der observeret tegn på udviklingstoksicitet (se pkt.
English: Lurasidone: ↑ expected (CYP3A4 inhibition)
Danish: Lurasidon:  forventet (CYP3A4 hæmning)
English: Haemophiliac patients: There have been reports of increased spontaneous bleeding in haemophiliac patients receiving antiretroviral protease inhibitors (see section 4.4).
Danish: Hæmofilipatienter: Der er rapporteret om øget spontan blødningstendens hos hæmofilipatienter, som blev behandlet med proteasehæmmere (se pkt.
English: Rhabdomyolysis: an increase in CPK, myalgia, myositis, and rarely, rhabdomyolysis, have been reported with protease inhibitors, more specifically in association with nucleoside analogues.
Danish: Rabdomyolyse: Der er i forbindelse med proteasehæmmere rapporteret om forhøjet CPK, myalgi og myositis.
English: In long-term carcinogenicity studies with fosamprenavir in mice and rats, there were increases in hepatocellular adenomas and hepatocellular carcinomas in mice at exposure levels equivalent to 0.1 to 0.3-fold those in humans given 700 mg of fosamprenavir plus 100 mg ritonavir twice daily, and increases in hepatocellular adenomas and thyroid follicular cell adenomas in rats at exposure levels equivalent to 0.3 to 0.6-fold those in humans given 700 mg of fosamprenavir plus 100 mg ritonavir twice daily.
Danish: I langtidskarcinogenicitetsstudier af fosamprenavir sås stigninger i hepatocellulære adenomaer og hepatocellulære carcinomaer hos mus ved eksponeringsniveauer 0,1-0,3 gange større end den humane dosis på 700 mg fosamprenavir plus 100 mg ritonavir 2 gange daglig.
English: Amprenavir: ↓ expected (Modest CYP3A4 induction)
Danish: Amprenavir:  forventet (Beskeden CYP3A4-induktion)
English: Rash (see text below “rash/cutaneous reactions”)
Danish: Udslæt (se nedenfor under ”Udslæt/hudreaktioner”) Angioødem
English: If you have any further questions about ritonavir or the other medicines prescribed, please ask your doctor or pharmacist.
Danish: Spørg lægen eller apotekspersonalet, hvis du har spørgsmål om ritonavir eller anden medicin.
English: • Increases in enzymes produced by the liver called transaminases, increases of an enzyme produced by the pancreas called lipase.
Danish: • stigning i mængden af leverenzymer (transaminaser) og pancreasenzym (lipase)
English: Glaxo Wellcome Operations, Priory Street, Ware, Hertfordshire SG12 0DJ, United Kingdom Glaxo Wellcome S.A., Avenida de Extremadura 3, 09400 Aranda de Duero Burgos, Spain Oral suspension
Danish: Filmovertrukne tabletter Glaxo Wellcome Operations, Priory Street, Ware, Hertfordshire SG12 0DJ, Storbritannien.
English: Hypersensitivity to fosamprenavir, amprenavir, or ritonavir, or to any of the excipients listed in section
Danish: Overfølsomhed over for fosamprenavir, amprenavir, ritonavir eller over for et eller flere af hjælpestofferne anført i pkt.
English: However you can still continue to take Telzir.
Danish: Du kan få udslæt, men du kan blive ved med at tage Telzir.
English: Nevirapine 200 mg twice daily
Danish: Nevirapin 200 mg 2 gange daglig
English: The recommended dose is 700 mg fosamprenavir twice daily with 100 mg ritonavir twice daily.
Danish: Den anbefalede dosis er 700 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir 2 gange daglig.
English: The tablets are capsule shaped, biconvex, pink coloured and marked with ‘GXLL7' on one side.
Danish: Tabletterne er præget `GXLL7´ på den ene side.
English: Methyl parahydroxybenzoate (E218) Propyl parahydroxybenzoate (E216) Polysorbate 80
Danish: Methylparahydroxybenzoat (E218) Propylparahydroxybenzoat (E216) Polysorbat 80
English: • doses of atorvastatin greater than 20 mg per day (used to lower cholesterol)
Danish: • atorvastatin doser på mere end 20 mg om dagen (mod forhøjet kolesterol i blodet)
English: In a randomised open-label study (ESS100732 - KLEAN) in antiretroviral naïve patients, fosamprenavir (700 mg) co-administered with low dose ritonavir (100 mg) in a twice daily regimen including abacavir / lamivudine (600 mg / 300 mg) fixed dose combination tablet once daily showed comparable efficacy over 48 weeks to lopinavir / ritonavir (400 mg / 100 mg) given twice daily in combination with abacavir / lamivudine (600 mg / 300 mg once daily).
Danish: I et randomiseret åbent studie (ESS100732 - KLEAN) hos antiretroviral-naive patienter, viste fosamprenavir (700 mg) med samtidig administration med en lavdosis ritonavir (100 mg) 2 gange daglig og en fast-dosis kombinationstablet af abacavir/lamivudin (600 mg/300 mg) én gang daglig, at have sammenlignelig effekt over 48 uger med lopinavir/ritonavir (400 mg/100 mg) givet 2 gange daglig i kombination med abacavir/lamivudin (600 mg/300 mg én gang daglig).
English: For adults with severe hepatic impairment (Child-Pugh score: 10-15): fosamprenavir should be used with caution and at a reduced dose of 300 mg fosamprenavir twice daily with 100 mg ritonavir once daily.
Danish: Til voksne med svært nedsat leverfunktion (Child-Pugh Score: 10-15) bør fosamprenavir anvendes med forsigtighed og i reduceret dosis på 300 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir en gang daglig.
English: (Mixed CYP3A4 induction/inhibition, Pgp induction)
Danish: (Kombineret CYP3A4induktion/hæmning, Pglykoprotein-induktion)
English: Not recommended
Danish: Ikke-fastende
English: FPV/RTV BID - Fosamprenavir with ritonavir twice daily, LPV/RTV BID - Lopinavir / ritonavir twice daily
Danish: FPV/RTV 2 gange daglig vs LPV/RTV 2 gange daglig
English: The use of Telzir concomitantly with halofantrine or lidocaine (systemic) is not recommended (see section 4.5).
Danish: Lægemidler - interaktioner Brugen af Telzir sammen med halofantrin eller lidocain (systemisk) kan ikke anbefales (se pkt.
English: Although the aetiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV-disease and/or long-term exposure to CART.
Danish: Ætiologien anses dog for at være multifaktoriel (omfattende anvendelse af kortikosteroider, alkoholforbrug, svær immunsuppression, højere Body Mass Index (BMI)).
English: Telzir tablet and oral suspension formulations, both given fasted, delivered equivalent plasma amprenavir AUC∞ values and the Telzir oral suspension formulation delivered a 14 % higher plasma amprenavir Cmax as compared to the oral tablet formulation.
Danish: Når Telzir tabletter og oral suspension blev administreret ved faste var plasma amprenavir AUC værdierne for de to formuleringer ækvivalente.
English: Therefore for adult patients the Telzir oral suspension should be taken without food and on an empty stomach (see section 4.2).
Danish: Voksne bør derfor tage Telzir oral suspension uden mad og på tom mave (se pkt.
English: Lopinavir: Cmax ↔* Lopinavir: AUC ↔* Lopinavir: Cmin ↔* * compared to lopinavir / ritonavir 400 mg/100 mg twice daily
Danish: Lopinavir: Cmax * Lopinavir: AUC * Lopinavir: Cmin * * sammenlignet med lopinavir / ritonavir 400 mg/100 mg 2 gange daglig
English: Despite reducing the dosing frequency of ritonavir, subjects with severe hepatic impairment had 64% higher ritonavir Cmax, 40% higher ritonavir AUC(0-24), and 38% higher ritonavir C12 than achieved in subjects with normal hepatic function receiving the standard fosamprenavir with ritonavir 700 mg / 100 mg twice daily regimen.
Danish: På trods af den reducerede doseringshyppighed af ritonavir havde personer med svært nedsat leverfunktion en 64 % højere plasma-Cmax, 40 % højere plasma-AUC(0-24) og 38 % højere plasma-C12-værdier for ritonavir i forhold til patienter med normal leverfunktion, der fik standardbehandlingen 700 mg fosamprenavir i kombination med 100 mg ritonavir 2 gange daglig.
English: In this patient population, the oral suspension should be taken without food and on an empty stomach.
Danish: Denne patientgruppe bør tage den orale suspension uden mad og på tom mave.
English: Proportion with HIV-1 RNA < 50 copies/ml
Danish: Andel med hiv-1-RNA < 50 kopier/ml
English: Compared to the historical adult population receiving fosamprenavir with ritonavir 700 mg / 100 mg twice daily, a subset of five pediatric subjects ages 6 to < 24-months receiving fosamprenavir / ritonavir 45/7 mg/kg twice daily demonstrated that despite an approximate 5-fold increase in fosamprenavir and ritonavir doses on a mg/kg basis, plasma amprenavir AUC(0-τ) was approximately 48 % lower, Cmax 26 % lower, and Cτ 29 % lower in the paediatric subjects.
Danish: Hos 5 børn i alderen 6 til 24 måneder, der blev behandlet med 45 mg fosamprenavir/kg og 7 mg ritonavir/kg 2 gange daglig, blev det påvist, at på trods af en 5-fold stigning i doser af fosamprenavir og ritonavir, var AUC(0-) for amprenavir i plasma cirka 48 % lavere, Cmax 26 % lavere og C 29 % lavere hos børnene.
English: Amprenavir and ritonavir levels may increase on stopping St John's wort.
Danish: Niveauet af amprenavir og ritonavir kan stige ved seponering af perikon.
English: 300 mg once daily
Danish: 300 mg én gang daglig
English: • Headache, feeling dizzy
Danish: • hovedpine, svimmelhed
English: Note that coadministration of Telzir with low dose ritonavir with sildenafil used for the treatment of pulmonary arterial hypertension is contraindicated (see section
Danish: Bemærk, at samtidig administration af Telzir med lavdosis ritonavir og sildenafil til behandling af pulmonal arteriel hypertension er kontraindiceret (se pkt.
English: (Mixed CYP3A4 induction/inhibition)
Danish: (Kombineret CYP3A4induktion/hæmning)
English: ritonavir and ombitasvir other HIV protease inhibitors and co-administered with and paritaprevir/ritonavir/ dasabuvir)
Danish: Paritaprevir (formuleret sammen med ritonavir og ombitasvir og administreret samtidig med dasabuvir)
English: BENZODIAZEPINES Midazolam
Danish: BENZODIAZEPINER
English: Herbal preparations containing St John's wort must not be combined with Telzir (see section 4.3).
Danish: Naturlægemidler indeholdende perikon må ikke anvendes sammen med Telzir (se pkt.
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING BOTTLE LABEL FOR TABLETS
Danish: ETIKET TIL BEHOLDER TIL TABLETTER
English: APV20002 is a 48 week, Phase II, open label study designed to evaluate the pharmacokinetics, safety, tolerability and antiviral activity of fosamprenavir with and without ritonavir in paediatric subjects 4 weeks to < 2 years of age.
Danish: Studiet er designet til at evaluere farmakokinetikken, sikkerheden, tolerancen og den antivirale aktivitet af fosamprenavir med og uden ritonavir hos børn i alderen 4 uger til 2 år.
English: Amprenavir: Cmax ↓ 13%* Amprenavir: AUC ↓ 26%* Amprenavir: Cmin ↓ 42 %* * compared to fosamprenavir / ritonavir 700 mg/100 mg twice daily
Danish: Amprenavir: Cmax  13 %* Amprenavir: AUC  26 %* Amprenavir: Cmin  42 %* * sammenlignet med fosamprenavir / ritonavir 700 mg/100 mg 2 gange daglig
English: 400 mg twice daily
Danish: 400 mg 2 gange daglig
English: LPV/RTV BID (N=103)
Danish: LPV/RTV 2 gange daglig (n=103)
English: Proportion with HIV-1 RNA < 400 copies/ml
Danish: Andel med hiv-1-RNA < 400 kopier/ml
English: Children can take the adult dose of one 700 mg Telzir tablet twice daily (with ritonavir 100 mg twice daily) if they weigh at least 39 kg and can swallow the tablets whole.
Danish: Børn kan tage voksendosis, én 700 mg Telzir tablet 2 gange daglig (sammen med 100 mg ritonavir 2 gange daglig), hvis de vejer mindst 39 kg og kan sluge tabletterne hele.
English: Telzir dose (TWICE DAILY)
Danish: Alder Kropsvægt Telzir dosis (2 GANGE DAGLIG)
English: Efavirenz 600 mg once daily
Danish: Efavirenz 600 mg én gang daglig