FrancophonIA/ELRC3.0 huggingface dataset:
English: Therefore, it is important that you follow the advice given in section 3 and wait at least 30 minutes before taking any other oral medicines or supplements.
Croatian: Stoga je važno da se pridržavate uputa navedenih u dijelu 3. i da pričekate najmanje 30 minuta prije uzimanja bilo kojeg drugog peroralnog lijeka ili nadomjestaka.
English: What is alendronate?
Croatian: Što je alendronat?
English: What VANTAVO is and what it is used for What you need to know before you take VANTAVO How to take VANTAVO
Croatian: Što je VANTAVO i za što se koristi Što morate znati prije nego počnete uzimati VANTAVO
English: • cancer, chemotherapy, radiotherapy, corticosteroids, angiogenesis inhibitors, smoking
Croatian: • rak, kemoterapija, radioterapija, kortikosteroidi, inhibitori angiogeneze, pušenje
English: What is osteoporosis?
Croatian: Što je osteoporoza?
English: Like muscles, bones need exercise to stay strong and healthy.
Croatian: Kao i mišićima, i kostima je potrebna tjelovježba kako bi ostale zdrave i čvrste.
English: Frequencies are defined as: very common (≥1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000)
Croatian: Učestalost nuspojava definirana je kategorijama: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000).
English: An Instruction Card is included in the carton for VANTAVO.
Croatian: Kartica s uputama priložena je u kutiji lijeka VANTAVO.
English: In both cases, the excreted radioactivity was almost exclusively as metabolites of the parent.
Croatian: U oba je slučaja radioaktivni materijal gotovo isključivo bio eliminiran u obliku metabolita osnovnog spoja.
English: There are no data on foetal risk in humans.
Croatian: Nema podatka o riziku za fetus u ljudi.
English: Pharmacotherapeutic group: Drugs for treatment of bone diseases, Bisphosphonates, combinations, ATC code: M05BB03
Croatian: Farmakoterapijska skupina: Lijekovi za liječenje bolesti kostiju, bisfosfonati, kombinacije, ATK oznaka: M05BB03
English: What VANTAVO contains
Croatian: Što VANTAVO sadrži
English: Currently available data for alendronic acid in the paediatric population is described in section 5.1.
Croatian: Trenutno dostupni podaci o primjeni alendronatne kiseline u pedijatrijskoj populaciji opisani su u dijelu 5.1.
English: PARTICULARS TO APPEAR WITHIN THE OUTER PACKAGING (CARTON)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU (KUTIJA)
English: Biotransformation There is no evidence that alendronate is metabolised in animals or humans.
Croatian: Biotransformacija Nema dokaza da se alendronat metabolizira u životinja niti u ljudi.
English: The time to onset of symptoms varied from one day to several months after starting treatment.
Croatian: Simptomi su se javljali u rasponu od jednoga dana do nekoliko mjeseci od početka liječenja.
English: • you are taking angiogenesis inhibitors (such as bevacizumab, or thalidomide) which are used in the treatment of cancer,
Croatian: • uzimate inhibitore angiogeneze (npr. bevacizumab ili talidomid), koji se koriste za liječenje raka,
English: Most patients had relief of symptoms after stopping treatment.
Croatian: U većine bolesnica simptomi su se povukli nakon prekida liječenja.
English: What is VANTAVO used for?
Croatian: Za što se koristi VANTAVO?
English: The optimal duration of bisphosphonate treatment for osteoporosis has not been established.
Croatian: Nije ustanovljeno optimalno trajanje liječenja osteoporoze bisfosfonatima.
English: It is important that you take VANTAVO for as long as your doctor prescribes the medicine.
Croatian: Važno je da uzimate VANTAVO sve dok Vam ga liječnik propisuje.
English: Concomitant administration of alendronate with coffee or orange juice reduced bioavailability by approximately 60 %.
Croatian: Istodobna primjena alendronata s kavom ili sokom od naranče smanjuje njegovu bioraspoloživost za oko 60%.
English: Although these usually hurt, breaks in the bones of the spine may go unnoticed until they cause height loss.
Croatian: Iako su obično bolni, prijelomi kralježaka mogu proći i nezapaženo, sve dok ne uzrokuju gubitak visine.
English: If you take more VANTAVO than you should If you take too many tablets by mistake, drink a full glass of milk and contact your doctor immediately.
Croatian: Ako greškom uzmete previše tableta, popijte punu čašu mlijeka i odmah se obratite liječniku.
English: • Do not take with juice or milk.
Croatian: • Nemojte uzimati lijek sa sokom niti mlijekom.
English: Although no clinical information is available, it is likely that, as in animals, elimination of alendronate via the kidney will be reduced in patients with impaired renal function.
Croatian: Iako ne postoje klinički podaci, izgledno je da će, kao i u životinja, eliminacija alendronata putem bubrega biti smanjena u ljudi s oštećenom funkcijom bubrega.
English: Colecalciferol and some of its active metabolites pass into breast milk.
Croatian: Kolekalciferol i neki njegovi aktivni metaboliti izlučuju se u majčino mlijeko.
English: - Inability to stand or sit upright for at least 30 minutes.
Croatian: Nemogućnost stajanja ili uspravnog sjedenja najmanje 30 minuta.
English: C]alendronate, approximately 50 % of the radioactivity was excreted in the urine within 72 hours and little or no radioactivity was recovered in the faeces.
Croatian: C]-alendronata, približno 50% radioaktivnosti eliminira se mokraćom tijekom 72 sata, dok je u fecesu ustanovljeno malo ili ništa radioaktivnosti.
English: Colecalciferol (vitamin D3)
Croatian: Kolekalciferol (vitamin D3)
English: Other beverages (including mineral water), food and some medicinal products are likely to reduce the absorption of alendronate (see section 4.5 and section 4.8).
Croatian: Drugi napici (uključujući i mineralnu vodu), hrana i neki lijekovi mogu smanjiti apsorpciju alendronata (vidjeti dijelove 4.5 i 4.8).
English: Elimination Following a single intravenous dose of [
Croatian: Nakon primjene jedne intravenske doze [
English: These transverse or short oblique, fractures can occur anywhere along the femur from just below the lesser trochanter to just above the supracondylar flare.
Croatian: Ti poprečni ili kratki kosi prijelomi mogu nastati na bilo kojem mjestu duž femura, od neposredno ispod malog trohantera do neposredno iznad suprakondilarnog ureza.
English: How to take VANTAVO tablets
Croatian: Kako uzimati VANTAVO tablete
English: Poor healing of these fractures has also been reported.
Croatian: Prijavljeno je i slabo cijeljenje takvih prijeloma.
English: In osteoporosis studies, alendronate was effective when administered at least 30 minutes before the first food or beverage of the day.
Croatian: U ispitivanjima liječenja osteoporoze alendronat je bio učinkovit kada se primjenjivao najmanje 30 minuta prije uzimanja prvog dnevnog obroka ili napitka.
English: • VANTAVO should only be swallowed after getting up for the day with a full glass of water (not less than 200 ml).
Croatian: • VANTAVO se mora progutati ujutro, nakon ustajanja, s punom čašom vode (najmanje 200 ml).
English: Therefore, patients must wait at least 30 minutes after taking alendronate before taking any other oral medicinal product (see sections 4.2 and 5.2).
Croatian: Zato bolesnice moraju pričekati najmanje 30 minuta nakon uzimanja alendronata prije nego što uzmu neki drugi peroralni lijek (vidjeti dijelove 4.2 i 5.2).
English: Eating a balanced diet Your doctor can advise you about your diet or whether you should take any dietary supplements.
Croatian: Uravnotežena prehrana Liječnik Vas može savjetovati o pravilnoj prehrani te o tome trebate li uzimati dodatke prehrani.
English: The amount of bisphosphonate incorporated into adult bone, and hence, the amount available for release back into the systemic circulation, is directly related to the dose and duration of bisphosphonate use (see section 5.2).
Croatian: Količina bisfosfonata koja se ugrađuje u kosti odraslih osoba, pa tako i količina koja se može ponovno vratiti u sistemsku cirkulaciju, izravno ovisi o primijenjenoj dozi i duljini primjene bisfosfonata (vidjeti dio 5.2).
English: Studies in animals have shown hypercalcaemia and reproductive toxicity with high doses of vitamin D (see section 5.3).
Croatian: Ispitivanja na životinjama pokazala su hiperkalcijemiju i reproduktivnu toksičnost kod primjene visokih doza vitamina D (vidjeti dio 5.3).
English: Package Leaflet: Information for the user
Croatian: Uputa o lijeku: Informacije za korisnicu
English: Other disorders affecting mineral metabolism (such as vitamin D deficiency and hypoparathyroidism) should also be effectively treated before starting this medicinal product.
Croatian: Također se moraju učinkovito liječiti i drugi poremećaji koji utječu na metabolizam minerala (kao što su nedostatak vitamina D i hipoparatiroidizam) prije početka liječenja ovim lijekom.
English: Bone and mineral metabolism Causes of osteoporosis other than oestrogen deficiency and ageing should be considered.
Croatian: Metobolizam minerala i kostiju Moraju se razmotriti i drugi uzroci osteoporoze osim nedostatka estrogena i starenja.
English: • Patients should not lie down for at least 30 minutes after taking VANTAVO and until after the first food of the day.
Croatian: • Bolesnice ne smiju leći najmanje 30 minuta nakon uzimanja VANTAVO tablete i dok ne pojedu svoj prvi dnevni obrok.
English: Laboratory test findings
Croatian: Nalazi laboratorijskih pretraga
English: Vitamin D3 is required for normal bone formation.
Croatian: Vitamin D3 potreban je za normalno stvaranje kostiju.
English: Further hydroxylation occurs prior to elimination.
Croatian: Prije eliminacije dolazi do daljnje hidroksilacije.
English: • talk to your doctor if you have ear pain, discharge from the ear, and/or an ear infection.
Croatian: • obratite se liječniku ako imate bol u uhu, iscjedak iz uha i/ili infekciju uha.
English: • you are taking corticosteroids (such as prednisone or dexamethasone) which are used in the treatment of such conditions as asthma, rheumatoid arthritis, and severe allergies,
Croatian: • uzimate kortikosteroide (npr. prednizon ili deksametazon), koji se koriste za liječenje bolesti kao što su astma, reumatoidni artritis i teške alergije,
English: Atypical fractures of the femur
Croatian: Netipični prijelomi femura
English: 2 tablets 4 tablets 12 tablets
Croatian: 2 tablete 4 tablete 12 tableta
English: For patients requiring dental procedures, there are no data available to suggest whether discontinuation of bisphosphonate treatment reduces the risk of osteonecrosis of the jaw.
Croatian: Za bolesnice koje trebaju stomatološki zahvat nema dostupnih podataka koji bi pokazali da prekid liječenja bisfosfonatima smanjuje rizik od razvoja osteonekroze čeljusti.
English: Talk to your doctor first and follow the advice given.
Croatian: Najprije razgovarajte s liječnikom i pridržavajte se dobivenih uputa.
English: What you need to know before you take VANTAVO
Croatian: Što morate znati prije nego počnete uzimati VANTAVO
English: • potency of the bisphosphonate (highest for zoledronic acid), route of administration (see above)
Croatian: • potentnost bisfosfonata (najveća za zoledronatnu kiselinu), put primjene (vidjeti gore) i kumulativna doza
English: - Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Croatian: - Preosjetljivost na djelatne tvari ili neku od pomoćnih tvari navedenih u dijelu 6.1.
English: Vitamin D is an essential nutrient, required for calcium absorption and healthy bones.
Croatian: D je esencijalna hranjiva tvar (nutrijens) nužna za apsorpciju kalcija i zdrave kosti.
English: Remember, take VANTAVO once each week on that same day for as long as your doctor prescribes it.
Croatian: Upamtite, uzmite VANTAVO jedanput na tjedan na isti odabrani dan, onoliko dugo koliko Vam je liječnik propisao.
English: 2 tablets 4 tablets 6 tablets 12 tablets
Croatian: 2 tablete 4 tablete 6 tableta 12 tableta
English: Do not use this medicine after the expiry date which is stated on the carton and the blister after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i blisteru iza oznake 'EXP'.
English: • Do not take with mineral water (still or sparkling).
Croatian: • Nemojte uzimati lijek s mineralnom vodom (gaziranom ili negaziranom).
English: • you are undergoing chemotherapy or radiotherapy,
Croatian: • primate kemoterapiju ili idete na zračenje,
English: If left untreated, however, it can result in broken bones.
Croatian: No, ako se ne liječi, može uzrokovati prijelome kostiju.
English: Your doctor has prescribed VANTAVO to treat your osteoporosis and because you are at risk of vitamin D insufficiency.
Croatian: Liječnik Vam je propisao VANTAVO za liječenje osteoporoze i zato što imate rizik od nedostatka vitamina D.
English: At the menopause, the ovaries stop producing the female hormone, oestrogen, which helps to keep a woman's skeleton healthy.
Croatian: U menopauzi jajnici prestaju stvarati ženski spolni hormon estrogen, koji pridonosi održanju zdrava skeleta u žena.
English: Insufficiency is associated with negative calcium balance, bone loss, and increased risk of skeletal fracture.
Croatian: Nedostatak je povezan s negativnim balansom kalcija, gubitkom kosti i povećanim rizikom od prijeloma kostiju.
English: FIT consisted of two placebo-controlled studies using alendronate daily (5 mg daily for two years and 10 mg daily for either one or two additional years):
Croatian: FIT ispitivanje sastojalo se od dva placebom kontrolirana ispitivanja u kojima je alendronat primjenjivan kao dnevna terapija (5 mg na dan u trajanju od dvije godine i 10 mg na dan u trajanju od još jedne ili dvije dodatne godine):
English: Protein binding in human plasma is approximately 78 %.
Croatian: Približno 78% doze veže se za proteine u ljudskoj plazmi.
English: What is VANTAVO?
Croatian: Što je VANTAVO?
English: In addition, a statistically significant reduction was found in the incidence of hip fractures (1.1 % vs. 2.2 %, a reduction of
Croatian: Osim toga statistički je značajno smanjena incidencija prijeloma kuka (1,1% naspram 2,2%, smanjenje od 51%);
English: These fractures occur after minimal or no trauma and some patients experience thigh or groin pain, often associated with imaging features of stress fractures, weeks to months before presenting with a completed femoral fracture.
Croatian: Ti prijelomi nastaju nakon minimalne ili nikakve traume, a neke bolesnice osjećaju bolove u natkoljenici ili preponama, koji su često povezani s radiološkim znakovima stres fraktura, više tjedana ili mjeseci prije nego što se razvije klinička slika potpunog prijeloma femura.
English: VANTAVO is only intended for use in postmenopausal women.
Croatian: VANTAVO je namijenjen isključivo ženama u postmenopauzi.
English: No specific information is available on the treatment of overdose with alendronate.
Croatian: Nisu raspoloživi specifični podaci o liječenju predoziranja alendronatom.
English: The bone formed during treatment with alendronate is of normal quality.
Croatian: Kost koja se formira tijekom liječenja alendronatom normalne je kakvoće.
English: VANTAVO is only intended for use in postmenopausal women and therefore it should not be used during pregnancy or in breast-feeding women.
Croatian: VANTAVO je namijenjen samo ženama u postmenopauzi i zbog toga se ne smije davati trudnicama ni dojiljama.
English: It is very important that the full dosing instructions are provided to, and are understood by the patient (see section 4.2).
Croatian: Zbog toga je vrlo važno da bolesnica dobije i razumije cjelovite upute o doziranju (vidjeti dio 4.2).
English: Alendronate is not excreted through the acidic or basic transport systems of the kidney in rats, and thus it is not anticipated to interfere with the excretion of other medicinal products by those systems in humans.
Croatian: Alendronat se u štakora ne eliminira kiselinskim ni baznim transportnim sustavom bubrega, pa se stoga ne očekuje da bi alendronat u čovjeka interferirao s eliminacijom drugih lijekova koji se eliminiraju putem tog sustava.
English: • stomach or peptic ulcers (sometimes severe or with bleeding),
Croatian: • želučani ili peptički vrijed (čir) (katkad teškog oblika ili praćen krvarenjem),
English: When radioactive vitamin D3 was administered to healthy subjects, the mean urinary excretion of radioactivity after 48 hours was 2.4 %, and the mean faecal excretion of radioactivity after 4 days was 4.9 %.
Croatian: Nakon primjene radioaktivnog vitamina D3 u zdravih ispitanika, prosječna je eliminacija radioaktivnosti mokraćom nakon 48 sati iznosilo 2,4%, dok je prosječna eliminacija fecesom nakon 4 dana bila 4,9%.
English: • nausea; vomiting,
Croatian: • mučnina, povraćanje,
English: Alendronate sodium is a bisphosphonate that inhibits osteoclastic bone resorption with no direct effect on bone formation.
Croatian: Natrijev alendronat je bisfosfonat koji inhibira resorpciju kosti posredovanu osteoklastima, bez izravnog utjecaja na formiranje kosti.
English: These could be signs of bone damage in the jaw (osteonecrosis) generally associated with delayed healing and infection, often following tooth extraction.
Croatian: Ovo mogu biti znakovi oštećenja kosti čeljusti (osteonekroze) koje je općenito povezano sa sporijim zacjeljivanjem i infekcijom, često nakon vađenja zuba.
English: In a clinical study of healthy adults a 4,000 IU daily dose of vitamin D3 for up to five months was not associated with hypercalciuria or hypercalcaemia.
Croatian: U kliničkom ispitivanju provedenom u zdravih odraslih osoba primjena vitamina D3 u dozi od 4000 IU na dan tijekom najdulje pet mjeseci nije bila povezana s hiperkalciurijom ni hiperkalcijemijom.
English: The content of vitamin D in VANTAVO is not suitable for correction of vitamin D deficiency.
Croatian: Količina vitamina D u lijeku VANTAVO nije primjerena za korekciju nedostatka vitamina D.
English: Patients should receive supplemental calcium if intake from diet is inadequate (see section 4.4).
Croatian: Bolesnice moraju uzimati dodatne količine kalcija ukoliko je unos hranom nedovoljan (vidjeti dio 4.4).
English: In the two-year extension of these studies BMD at the spine and trochanter continued to increase and BMD at the femoral neck and total body were maintained.
Croatian: U dvogodišnjem nastavku tih ispitivanja BMD kralježnice i trohantera nastavio je rasti, dok su njegove vrijednosti za vrat bedrene kosti i cijeloga tijela ostale očuvane.
English: In clinical studies there was no age-related difference in the efficacy or safety profiles of alendronate.
Croatian: U kliničkim ispitivanjima nisu utvrđene razlike u profilima djelotvornosti ili sigurnosti primjene alendronata vezane za dob.
English: Osteoporosis is a thinning and weakening of the bones.
Croatian: Osteoporoza je smanjenje gustoće i slabljenje kostiju.
English: Circulating vitamin D3 is bound to vitamin D-binding protein.
Croatian: Cirkulirajući vitamin D3 veže se za protein koji vezuje vitamin D.
English: • FIT 2: A four-year study of 4,432 patients with low bone mass but without a baseline vertebral fracture.
Croatian: • FIT 2: četverogodišnje ispitivanje koje je uključilo 4432 bolesnice sa smanjenom koštanom masom, ali bez prethodnih prijeloma kralježaka pri uključivanju u ispitivanje.
English: In post-marketing experience, these symptoms have rarely been severe and/or incapacitating (see section 4.8).
Croatian: Nakon stavljanja lijeka u promet ovi su simptomi rijetko bili teški i/ili takvi da su uzrokovali onesposobljenost (vidjeti dio 4.8).
English: • allergic reactions such as hives; swelling of the face, lips, tongue and/or throat, possibly causing difficulty breathing or swallowing; severe skin reactions.
Croatian: • alergijske reakcije kao što su koprivnjača, oticanje lica, usana, jezika i/ili grla, koje može uzrokovati otežano disanje ili gutanje, teške kožne reakcije,
English: However, the incidences of decreases in serum calcium to < 8.0 mg/dl (2.0 mmol/l) and serum phosphate to  2.0 mg/dl (0.65 mmol/l) were similar in both treatment groups.
Croatian: Incidencije sniženja serumskog kalcija na < 8,0 mg/dl (2,0 mmol/l) i serumskog fosfata na  2,0 mg/dl (0,65 mmol/l) bile su slične u obje ispitivane skupine.
English: They should not take two tablets on the same day but should return to taking one tablet once a week, as originally scheduled on their chosen day.
Croatian: Bolesnice ne smiju uzeti dvije tablete u istom danu, nego moraju nastaviti s uzimanjem jedne tablete jedanput na tjedan, u dan koji su odabrale na početku liječenja.
English: You may be advised to have a dental check-up before starting treatment with VANTAVO.
Croatian: Liječnik će Vam možda savjetovati da obavite kontrolu kod stomatologa prije nego počnete uzimati VANTAVO.
English: The terminal half-life in humans is estimated to exceed ten years, reflecting release of alendronate from the skeleton.
Croatian: Procjenjuje se da je u čovjeka terminalni poluvijek alendronata dulji od 10 godina, što odražava njegovo otpuštanje iz skeleta.
English: Contact your doctor if you experience pain, weakness or discomfort in your thigh, hip or groin as this may be an early indication of a possible fracture of the thigh bone,
Croatian: Obavijestite svog liječnika ako osjetite bolove, slabost ili nelagodan osjećaj u bedru, kuku ili preponama, jer to mogu biti rani znakovi mogućeg prijeloma bedrene kosti.
English: Mark the day of the week that best fits your schedule: MON
Croatian: Označite dan u tjednu koji najviše odgovara Vašim uobičajenim aktivnostima: PON
English: VANTAVO should not be used during pregnancy.
Croatian: VANTAVO se ne smije primjenjivati tijekom trudnoće.
English: The recommended dose is one tablet once weekly.
Croatian: Preporučena doza je jedna tableta jedanput na tjedan.
English: Therefore, somewhat greater accumulation of alendronate in bone might be expected in patients with impaired renal function (see section 4.2).
Croatian: Stoga se može očekivati donekle povećano nakupljanje lijeka u kostima u bolesnica s oštećenom bubrežnom funkcijom (vidjeti dio 4.2).
English: It is very important to follow instructions 2), 3), 4) and 5) to help the VANTAVO tablet reach your stomach quickly and help reduce the chance of irritating your gullet (oesophagus - the tube that connects your mouth with your stomach).
Croatian: Vrlo je važno pridržavati se uputa navedenih pod 2), 3), 4) i 5) kako bi VANTAVO tableta brzo stigla do želuca i kako bi se smanjila vjerojatnost da će nadražiti jednjak (jednjak je cijev koja spaja usta sa želucem).
English: Results are insufficient to support the use of alendronate sodium in paediatric patients with osteogenesis imperfecta.
Croatian: Rezultati nisu dostatni da opravdaju primjenu natrijevog alendronata u pedijatrijskih bolesnika s osteogenesis imperfecta .
English: • symptoms of low blood calcium levels including muscle cramps or spasms and/or tingling sensation in the fingers or around the mouth,
Croatian: • simptomi niskih razina kalcija u krvi, uključujući grčeve ili stezanje u mišićima i/ili trnce u prstima ili oko usta,
English: VANTAVO must be taken with water only (not mineral water) at least 30 minutes before the first food, beverage, or medicinal product (including antacids, calcium supplements and vitamins) of the day.
Croatian: VANTAVO se mora uzimati samo s vodom (ne mineralnom vodom) najmanje 30 minuta prije uzimanja prvoga dnevnog obroka, napitka ili drugih lijekova (uključujući antacide, nadomjestke kalcija i vitamine).
English: Since Non Steroidal Anti-Inflammatory Drug (NSAID) use is associated with gastrointestinal irritation, caution should be used during concomitant use with alendronate.
Croatian: Budući da je primjena nesteroidnih protuupalnih lijekova (NSAIL) povezana s nadražajem gastrointestinalne sluznice, potreban je oprez tijekom istodobne primjene s alendronatom.
English: If you miss a dose, take only one VANTAVO tablet on the morning after you remember.
Croatian: Ako propustite uzeti dozu, uzmite samo jednu VANTAVO tabletu sljedećeg jutra nakon što se sjetite.
English: 4) Do not take VANTAVO at bedtime or before getting up for the day.
Croatian: 4) Nemojte uzimati VANTAVO navečer prije spavanja niti ujutro prije ustajanja.