FrancophonIA/ELRC3.0 huggingface dataset:
English: In a clinical study investigating the interaction of rifampicin 600 mg once daily and saquinavir 1000 mg with ritonavir 100 mg twice daily in healthy volunteers, severe hepatocellular toxicity with transaminase elevations up to > 20-fold the upper limit of normal after 1 to 5 days of co-administration was noted.
Slovenian: V klinični študiji, s katero so pri zdravih prostovoljcih raziskali medsebojno delovanje 600 mg rifampicina enkrat na dan ter 1000 mg sakvinavirja s 100 mg ritonavirja dvakrat na dan, so po 1 do 5
English: For specific dosing information in patients with renal impairment, refer to the Summary of Product Characteristics (SPC) of the co-administered protease inhibitor.
Slovenian: Za specifične informacije o odmerjanju pri bolnikih z okvaro ledvic glejte povzetek glavnih značilnosti (SPC - Summary of Product Characteristics) sočasno uporabljenega zaviralca proteaz.
English: Effect on Coadministered Medicinal Products AUC
Slovenian: Vpliv na AUC
English: Lovastatin, simvastatin Increased plasma concentrations of lovastatin and simvastatin; thereby, increasing the risk of myopathy including rhabdomyolysis (see section
Slovenian: Zvišana koncentracija lovastatina in simvastatina v plazmi; s tem se poveča tveganje za miopatijo, vključno z rabdomiolizo (glejte poglavje 4.5).
English: Ritonavir concentrations in this study were highly variable and somewhat lower than those obtained in adults receiving 600 mg (approximately 330 mg/m²) twice daily.
Slovenian: okuženih s HIV, mlajših od 2 let, ki so dobivali odmerke od 350 do 450 mg/m2 dvakrat na dan. Koncentracije ritonavirja so bile v tej študiji zelo spremenljive in nekoliko nižje kot pri odraslih, ki so dobivali 600 mg (približno 330 mg/m2) dvakrat na dan.
English: Ritonavir increases plasma concentrations of simeprevir as a result of CYP3A4 inhibition.
Slovenian: Ritonavir zviša plazemske koncentracije simeprevirja, kar je posledica zaviranja CYP3A4.
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING NORVIR FILM-COATED TABLETS BOTTLE LABEL TEXT - 3 BOTTLES
Slovenian: PODATKI NA PRIMARNI OVOJNINI NORVIR FILMSKO OBLOŽENE TABLETE - Besedilo na nalepki za plastenko - 3 plastenke
English: These are listed earlier in section 2,
Slovenian: Ta zdravila so našteta zgoraj, v 2.
English: • if Norvir is used to boost the effects of certain other anti-HIV medicines the typical dose for adults is 1 to 2 tablets once or twice daily.
Slovenian: Priporočeni odmerki zdravila Norvir so: - če zdravilo Norvir uporabljate za stopnjevanje učinkov drugih zdravil proti HIV, je odmerek za odrasle praviloma 1 do 2 filmsko obloženi tableti enkrat ali dvakrat na dan. Za podrobna navodila o odmerjanju (vključno z odmerjanjem za otroke) glejte navodila za uporabo drugih zdravil proti
English: (µg•h/ml) t½ (h)
Slovenian: (μg/ml)
English: Fill the syringe a. Push the plunger all the way into syringe.
Slovenian: Napolnite brizgo a. Potisnite bat do konca v brizgo.
English: Increased plasma concentrations of amiodarone, bepridil, dronedarone, encainide, flecanide, propafenone, quinidine.
Slovenian: Zvišana koncentracija amiodarona, bepridila, dronedarona, enkainida, flekainida, propafenona, kinidina v plazmi.
English: ↑ 13-fold
Slovenian: ↑ 13-krat
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, inducira oksidacijo s CYP2C9 in glukuronidacijo, zato je treba pričakovati, da zniža koncentracijo antiepileptičnih zdravil v plazmi.
English: 1250 q12h
Slovenian: 1250 na 12 ur
English: Antiarrthymics
Slovenian: Antiaritmiki
English: - Bosentan, riociguat (used for pulmonary arterial hypertension) as Norvir may increase the blood levels of this medicine.
Slovenian: − Bosentan, riociguat (za pljučno arterijsko hipertenzijo), ker lahko zdravilo Norvir poveča koncentracijo tega zdravila v krvi.
English: Increased plasma concentrations of fusidic acid and ritonavir.
Slovenian: Zvišana koncentracija fusidne kisline in ritonavirja v plazmi.
English: Pethidine Norpethidine metabolite
Slovenian: Petidin Presnovek norpetidina
English: HMG Co-A Reductase Inhibitors
Slovenian: Zaviralci reduktaze HMG Co-A
English: − anticancer treatments (e.g. abemaciclib; afatinib, apalutamide, ceritinib, encorafenib, dasatinib,
Slovenian: − zdravila proti raku (npr. abemaciklib, afatinib, apalutamide, ceritinib, enkorafenib, dasatinib,
English: Repeated dose toxicity studies in animals identified major target organs as the liver, retina, thyroid gland and kidney.
Slovenian: 5.3 Predklinični podatki o varnosti V študijah toksičnosti pri ponavljajočih se odmerkih na živalih so kot glavne ciljne organe ugotovili jetra, mrežnico, ščitnico in ledvice.
English: 300 q24h
Slovenian: 300 na 24 ur
English: However, if the benefit outweighs the risk, coadministration of bedaquiline with ritonavir must be done with caution.
Slovenian: Vendar pa je , če je korist večja od tveganja, pri sočasni uporabi bedakilina z ritonavirjem potrebna previdnost.
English: 600 q24h
Slovenian: 600 na 24 ur
English: Adverse reactions of nausea, dizziness, hypotension and syncope have been observed in single dose interaction studies in healthy volunteers (see section 4.5)
Slovenian: V študijah medsebojnega delovanja z enim odmerkom pri zdravih prostovoljcih so zabeležili neželene učinke: navzeo, omotico, hipotenzijo in sinkopo (glejte poglavje 4.5).
English: Lopinavir co-formulated with ritonavir (lopinavir/ritonavir) 400 mg/100 mg or 800 mg/200 mg. Saquinavir 1000 mg twice daily with ritonavir 100 mg twice daily in ART experienced patients.
Slovenian: Amprenavir 600 mg dvakrat na dan z ritonavirjem 100 mg dvakrat na dan Atazanavir 300 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan Fosamprenavir 700 mg dvakrat na dan z ritonavirjem 100 mg dvakrat na dan Lopinavir v kombinaciji z ritonavirjem (lopinavir/ritonavir) 400 mg/100 mg ali 800 mg/200 mg Sakvinavir 1000 mg dvakrat na dan z ritonavirjem 100 mg dvakrat na dan pri bolnikih, ki so bili predhodno zdravljeni z antiretrovirusno terapijo (ART).
English: Digoxin levels should be monitored more intensively than usual during this period, with dose adjustments made, as necessary, based on clinical, electrocardiographic and digoxin level findings.
Slovenian: odmerek pa prilagajati, kot je potrebno glede na klinični in elektrokardiografski izvid ter koncentracijo digoksina.
English: If the benefit outweighs the risk, co-administration of bedaquiline with ritonavir must be done with caution.
Slovenian: Če je korist večja od tveganja, je pri sočasni uporabi bedakilina z ritonavirjem potrebna previdnost.
English: For further dosage recommendations, refer to the product information of other protease inhibitors approved for co-administration with ritonavir.
Slovenian: Za nadaljnja priporočila o odmerjanju glejte navodilo za uporabo drugega zaviralca proteaz, odobrenega za sočasno uporabo z ritonavirjem.
English: Each sachet of Norvir contains 100 mg ritonavir.
Slovenian: Vsaka vrečica zdravila Norvir vsebuje 100 mg ritonavirja.
English: Pharmaco-therapeutic group: antiviral for systemic use, protease inhibitors ATC code: J05AE03
Slovenian: Oznaka ATC: J05AE03
English: • muscle aches (pain), tenderness or weakness
Slovenian: - bolečine v mišicah, občutljivost ali šibkost
English: ↑ 178% ND
Slovenian: Indinavir3 ↑ 178 % ND Ritonavir ↑ 72 % ND
English: 500 mg in the morning and 500 mg in the evening
Slovenian: 500 mg zjutraj in 500 mg zvečer
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING NORVIR FILM-COATED TABLETS - Bottle Label Text
Slovenian: PODATKI NA PRIMARNI OVOJNINI NORVIR FILMSKO OBLOŽENE TABLETE - Besedilo na nalepki za plastenko
English: 100 q24h
Slovenian: 100 na 24 ur
English: The co-administration of riociguat with Norvir is not recommended (see section 4.4 and refer to riociguat SmPC).
Slovenian: Sočasna uporaba riociguata z zdravilom Norvir ni priporočljiva (glejte poglavje 4.4 in glejte povzetek glavnih značilnosti zdravila za riociguat).
English: • reduced kidney function
Slovenian: - zmanjšano delovanje ledvic
English: In addition, serum concentrations may be increased when co-administered with ritonavir resulting in the potential for serious adverse events including seizure.
Slovenian: Poleg tega se ob sočasni uporabi z ritonavirjem lahko povečajo serumske koncentracije, kar lahko vodi k pojavu resnih neželenih učinkov,
English: 200 q12h, 13 days
Slovenian: 200 na 12h, 13 dni
English: Increased plasma concentrations of vardenafil (see section 4.4. and 4.5).
Slovenian: Zvišana plazemska koncentracija vardenafila (glejte poglavji 4.4 in
English: Each sachet contains 100 mg of ritonavir.
Slovenian: Vsaka vrečica vsebuje 100 mg ritonavirja.
English: • if Norvir is used to boost the effects of other anti-HIV medicines, the typical dose for adults is 1 or 2 sachets once or twice daily.
Slovenian: Priporočeni odmerki zdravila Norvir so: - če zdravilo Norvir uporabljate za stopnjevanje učinkov drugih zdravil proti HIV, je odmerek za odrasle praviloma ena ali dve vrečici enkrat ali dvakrat na dan. Za podrobna navodila o odmerjanju (vključno z odmerjanjem za otroke) glejte navodilo za uporabo drugih zdravil proti
English: − The tablet coating is composed of: hypromellose, titanium dioxide, macrogols, hydroxypropyl cellulose, talc, colloidal anhydrous silica, polysorbate 80.
Slovenian: Filmska obloga: hipromeloza titanov dioksid (E171) makrogoli hidroksipropilceluloza smukec silicijev dioksid, koloidni, brezvodni polisorbat 80
English: If trazodone is coadministered with ritonavir, the combination should be used with caution, initiating trazodone at the lowest dosage and monitoring for clinical response and tolerability.
Slovenian: trazodon uvesti v najmanjšem odmerku ter kontrolirati bolnikov klinični odziv in prenašanja.
English: • upset stomach or indigestion
Slovenian: - kašelj - razdražen želodec ali slaba prebava
English: Pour the powder into the cup a. Tear open the sachet.
Slovenian: Vsujte prašek v posodico a. Odprite blazinico tako, da jo pretrgate.
English: Talk to your doctor before taking Norvir.
Slovenian: Pred začetkom jemanja zdravila Norvir se posvetujte z zdravnikom.
English: 262.5 mg (26.4 ml) twice daily
Slovenian: 262,5 mg (26,4 ml) dvakrat na dan
English: − ergonovine, methylergonovine (used to stop excessive bleeding that may occur following childbirth or an abortion);
Slovenian: - ergonovin, metilergonovin (uporabljata se za ustavljanje čezmerne krvavitve, ki se lahko pojavi po porodu ali splavu), - klorazepat, diazepam, estazolam, flurazepam, triazolam ali peroralni (zaužiti) midazolam
English: - Colchicine (for gout) as Norvir may raise the blood levels of this medicine.
Slovenian: - Kolhicin (za zdravljenje protina), ker zdravilo Norvir lahko poveča koncentracijo tega zdravila v krvi.
English: 500 q12h
Slovenian: 500 na 12 ur
English: If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Slovenian: Če se bolezen jeter pri takšnih bolnikih poslabša,
English: − The other tablet ingredients are: copovidone, sorbitan laurate, anhydrous calcium hydrogen phosphate, colloidal anhydrous silica, sodium stearyl fumarate.
Slovenian: Vsebina tablete: kopovidon sorbitan lavrat kalcijev hidrogenfosfat, brezvodni silicijev dioksid, koloidni, brezvodni natrijev stearilfumarat
English: Increased methadone dose may be necessary when concomitantly administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer due to induction of glucuronidation.
Slovenian: Zaradi indukcije glukuronidacije utegne biti med sočasno uporabo metadona in ritonavirja, odmerjanega kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, potreben večji odmerek metadona.
English: Very common Arthralgia and back pain Common Myositis, rhabdomyolysis, myalgia, myopathy/CPK increased
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva zelo pogosti artralgija in bolečine v hrbtu pogosti miozitis, rabdomioliza, mialgija, miopatija/zvišana CPK
English: Reduction in the antiretroviral activity of ritonavir is primarily associated with the protease mutations V82A/F/T/S and I84V.
Slovenian: Zmanjšanje protiretrovirusnega delovanja ritonavirja je v prvi vrsti povezano z mutacijami proteaz
English: 300 mg in the morning and 300 mg in the evening
Slovenian: 300 mg zjutraj in 300 mg zvečer
English: − clozapine, pimozide, (used to treat abnormal thoughts or feelings);
Slovenian: (uporabljajo se proti nespečnosti in/ali za odpravljanje tesnobnosti), - klozapin, pimozid (uporabljata se za zdravljenje nenormalnih misli ali čustev),
English: Be careful not to pull the plunger out.
Slovenian: Pazite, da bata ne potegnete ven. d. Ponovno potrkajte po brizgi.
English: Ritonavir has selective affinity for the HIV protease and has little inhibitory activity against human aspartyl proteases.
Slovenian: HIV-proteaze in le malo zavira človeške aspartilproteaze.
English: The co-administration of vorapaxar with Norvir is not recommended (see section 4.4 and refer to the vorapaxar SmPC).
Slovenian: Sočasna uporaba vorapaksarja z zdravilom Norvir ni priporočljiva (glejte poglavje 4.4 in povzetek glavnih značilnosti zdravila za vorapaksar).
English: 400 mg in the morning and 300 mg in the evening
Slovenian: 400 mg zjutraj in 300 mg zvečer
English: Common Increased urination, renal impairment (e.g. oliguria, elevated creatinine)
Slovenian: Bolezni sečil pogosti povečano uriniranje, okvara ledvic (oligurija,
English: Caution should be exercised in administering ceritinib with Norvir.
Slovenian: Pri uporabi ceritiniba z zdravilom Norvir je potrebna previdnost.
English: Ritonavir inhibits CYP3A-mediated metabolism of ketoconazole.
Slovenian: Ritonavir zavira presnovo ketokonazola s CYP3A.
English: 500 mg in the morning and 400 mg in the evening
Slovenian: 500 mg zjutraj in 400 mg zvečer
English: When ritonavir is used as a pharmacokinetic enhancer with other protease inhibitors the Summary of Product Characteristics for the particular protease inhibitor must be consulted.
Slovenian: Če je ritonavir uporabljen kot farmakokinetični stopnjevalec drugih zaviralcev proteaz, je treba glede kontraindikacij upoštevati povzetek glavnih značilnosti sočasno uporabljenega zaviralca proteaz.
English: − pethidine, piroxicam, propoxyphene (used to relieve pain);
Slovenian: - petidin, piroksikam, propoksifen (uporabljajo se za lajšanje bolečin),
English: Amprenavir ↑ 2.4 fold ↑ 11 fold
Slovenian: Amprenavir ↑ 2,4-krat
English: Children and adolescents (2 years of age and above) The recommended dosage of Norvir powder for suspension in children is 350 mg/m² by mouth twice daily and should not exceed 600 mg twice daily.
Slovenian: Otroci in mladostniki (od 2. leta dalje) Priporočeno odmerjanje zdravila Norvir prašek za peroralno suspenzijo pri otrocih je 350 mg/m2
English: Ritonavir dosed as an antiretroviral agent is likely to inhibit CYP2D6 and as a result is expected to increase concentrations of amphetamine and its derivatives.
Slovenian: CYP2D6, zato je treba pričakovati, da zviša koncentracijo amfetamina in njegovih derivatov.
English: Increased plasma concentrations of neratinib which may increase the potential for serious and/or life-threatening reactions including hepatotoxicity (see section 4.5).
Slovenian: Zvišana koncentracija neratiniba v plazmi, ki lahko poveča tveganje za resne in/ali življenje ogrožajoče reakcije, vključno s hepatotoksičnostjo (glejte poglavje
English: - The other ingredients are copovidone; sorbitan laurate; silica, colloidal anhydrous.
Slovenian: - Pomožne snovi so kopovidon; sorbitan lavrat; brezvodni koloidni silicijev dioksid.
English: − immune system (e.g. cyclosporine, tacrolimus, everolimus);
Slovenian: diltiazem in nifedipin); − zdravila z delovanjem na imunski sistem (npr. ciklosporin, takrolimus, everolimus);
English: 10, single dose 600 q12h ↑ 153% ↑ 55% Inhibition of CYP3A and P-gp lead to increased plasma levels and pharmacodynamic effects of rivaroxaban which may lead to an increased bleeding risk.
Slovenian: Zavrtje CYP3A in P-gp poveča koncentracijo rivaroksabana v plazmi in njegove farmakodinamične učinke; to lahko poveča tveganje za krvavitve.
English: • laboratory test results:
Slovenian: - zvišana telesna temperatura - hujšanje - rezultati laboratorijskih preiskav:
English: c. Slowly pull the plunger back to the 10 ml mark on the syringe (see Figure 2).
Slovenian: c. Počasi potegnite bat nazaj do oznake 10 ml na brizgi
English: Ritonavir may modify P-glycoprotein mediated fexofenadine efflux when dosed as an antriretroviral agent or as a pharmacokinetic enhancer resulting in increased concentrations of fexofenadine.
Slovenian: Ritonavir, odmerjan kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, lahko spremeni s P-glikoproteinom posredovani iztok feksofenadina in tako zviša koncentracijo feksofenadina.
English: 400 q12h
Slovenian: 400 na 12 ur
English: Hepatic impairment
Slovenian: - glavobol - omotica
English: Medicinal Products within Class
Slovenian: Zdravila v skupini
English: − levothyroxine (used to treat thyroid probems);
Slovenian: − levotiroksin (za zdravljenje težav s ščitnico);
English: ↑ 2.4-fold
Slovenian: ↑ 2,4-krat
English: Due to reductions in ethinyl estradiol concentrations, barrier or other non-hormonal methods of contraception should be considered with concomitant ritonavir use when dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Slovenian: Med sočasno uporabo ritonavirja, odmerjanega kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, je treba zaradi znižanja koncentracije etinilestradiola uporabljati pregradne ali druge nehormonske načine kontracepcije.
English: Package leaflet: Information for the user Norvir 100 mg film-coated tablets ritonavir
Slovenian: Navodilo za uporabo Norvir 100 mg filmsko obložene tablete ritonavir
English: Tear open sachet (see Figure 3).
Slovenian: Odprite vrečico (glejte sliko 3).
English: Ritonavir medicinal product level decreased
Slovenian: Znižanje koncentracije ritonavirja
English: The mean average change from baseline over 16 weeks for HIV RNA levels was -0.79 log10 (maximum mean decrease: 1.29 log10) in the ritonavir group versus-0.01 log10 in the control group.
Slovenian: Srednja povprečna sprememba v primerjavi z izhodiščno koncentracijo HIV RNA v 16 tednih je bila - 0,79 log10
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent inhibits CYP3A4 and as a result is expected to increase the plasma concentrations of calcium channel antagonists.
Slovenian: Ritonavir, odmerjan kot farmakokinetični stopnjevalec ali kot protiretrovirusno zdravilo, zavira CYP3A4, zato je treba pričakovati, da zviša koncentracijo antagonistov kalcijevih kanalčkov v plazmi.
English: 600 q12h
Slovenian: 600 na 12 ur
English: ↑ 11-fold
Slovenian: Tipranavir ↑ 11-krat
English: Concentrations of colchicine are expected to increase when coadministered with ritonavir.
Slovenian: Pri sočasni uporabi kolhicina z ritonavirjem je mogoče pričakovati zvišano koncentracijo kolhicina.
English: Ritonavir co-administration is likely to result in increased plasma concentrations of amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, and quinidine and is therefore contraindicated (see section 4.3).
Slovenian: bepridila, dronedarona, enkainida, flekainida, propafenona in kinidina v plazmi in je zato kontraindicirana (glejte poglavje 4.3).
English: ↑ 15-fold ↑ 5-fold
Slovenian: ↑ 5-krat Ritonavir ↔ ↔
English: The concomitant use of tadalafil for the treatment of erectile dysfunction with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer should be with caution at reduced doses of no more than 10 mg tadalafil every 72 hours with increased monitoring for adverse reactions (see section 4.4).
Slovenian: 200 na 12 ur ↑ 124 % Med sočasno uporabo tadalafila za zdravljenje erektilne disfunkcije in ritonavirja, odmerjanega kot protiretrovirusno zdravilo ali farmakokinetični stopnjevalec, je potrebna previdnost; odmerek tadalafila je treba zmanjšati in ne sme preseči 10 mg na 72 ur.
English: In intent to treat analyses, 50% and 57% of patients in the 350 and 450 mg/m2 dose groups, respectively, achieved reduction in plasma HIV-1 RNA to ≤ 400 copies/ml at Week 48.
Slovenian: RNA v plazmi na ≤ 400 izvodov/ml do 48. tedna doseglo 50 % bolnikov v skupini s 350 mg/m2 in 57 % bolnikov v skupini s 450 mg/m2.
English: Clinical trials confirmed the safety and efficacy of 600 mg amprenavir twice daily with ritonavir 100 mg twice daily.
Slovenian: Klinična preskušanja so potrdila varnost in učinkovitost 600 mg amprenavirja dvakrat na dan z ritonavirjem 100 mg dvakrat na dan. Za dodatne informacije glejte povzetek glavnih značilnosti za amprenavir.
English: Co-administered Medicinal Products
Slovenian: sočasno uporabljenega zdravila
English: Package leaflet: Information for the user Norvir 100 mg powder for oral suspension ritonavir
Slovenian: Navodilo za uporabo Norvir 100 mg prašek za peroralna suspenzijo ritonavir
English: Very common Abdominal pain (upper and lower), nausea, diarrhoea (including severe with electrolyte imbalance), vomiting, dyspepsia
Slovenian: Bolezni prebavil zelo pogosti bolečine v trebuhu (v zgornjem in spodnjem predelu), navzea, driska (vključno s hudo drisko in elektrolitskimi motnjami), bruhanje, dispepsija pogosti anoreksija, flatulenca, razjede v ustih, gastrointestinalna krvavitev, gastroezofagealna refluksna bolezen, pankreatitis
English: Twice Daily Dose 350 mg/m2
Slovenian: odmerek 250 mg/m2 dvakrat na dan odmerek 300 mg/m2 dvakrat na dan odmerek 350 mg/m2 dvakrat na dan
English: You must not take Norvir with sildenafil if you suffer from pulmonary arterial hypertension (see also section 2.
Slovenian: Zdravila Norvir ne smete jemati s sildenafilom, če imate pljučno arterijsko hipertenzijo (glejte tudi poglavje 2, Kaj morate vedeti, preden boste vi ali vaš otrok vzeli zdravilo Norvir).
English: Medicinal Product Class
Slovenian: FARMAKOLOŠKE LASTNOSTI
English: Common Hypersensitivity, including urticaria and face oedema.
Slovenian: Bolezni imunskega sistema pogosto preobčutljivost, vključno z urtikarijo in edemom obraza redko anafilaksija
English: (erectile dysfunction) under their doctor's supervision (see the section on Other medicines and Norvir);
Slovenian: Bolniki brez te bolezni lahko sildenafil uporabljajo za impotenco (erektilno disfunkcijo) pod nadzorom svojega zdravnika (glejte poglavje Druga zdravila in zdravilo
English: Darunavir 800 mg once daily with ritonavir 100 mg once daily in ART-naïve patients.
Slovenian: Darunavir 800 mg enkrat na dan z ritonavirjem 100 mg enkrat na dan pri bolnikih, ki še niso dobivali ART.
English: Concomitant administration of Norvir and quetiapine is contraindicated as it may increase quetiapine-related toxicity (see section 4.3).
Slovenian: Sočasna uporaba zdravila Norvir in kvetiapina je kontraindicirana, ker lahko poveča toksičnost, povezano s kvetiapinom
English: Refer to the Summary of Product Characteristics for atazanavir for further details.
Slovenian: Za dodatne informacije glejte povzetek glavnih značilnosti za atazanavir.
English: 500 q12h, 10
Slovenian: 500 na 12 ur ↑ 11-krat
English: Desipramine
Slovenian: Odmerjanje
English: ↓ 40% ND Ritonavir increases the serum levels of tipranavir as a result of CYP3A inhibition.
Slovenian: ↑ 29-krat Ritonavir ↓ 40 % ND Ritonavir zavira CYP3A in tako zviša koncentracijo tipranavirja v serumu.
English: Concomitant use of avanafil with ritonavir is contraindicated (see section 4.3).
Slovenian: Sočasna uporaba avanafila z ritonavirjem je kontraindicirana (glejte poglavje 4.3).
English: Co-administration of ritonavir with these medicinal products is expected to substantially increase their concentrations and may result in associated adverse reactions such as hypotension and prolonged erection (see section 4.5).
Slovenian: Pričakovati je treba, da sočasna uporaba ritonavirja in teh zdravil bistveno zviša njihovo koncentracijo in lahko povzroči z njimi povezane neželene učinke, npr.