FrancophonIA/ELRC3.0 huggingface dataset:
English: − Hypersensitivity to the active substances or to any of the excipients listed in section 6.1, or to other sulphonamide-derived substances.
Slovenian: − Preobčutljivost na učinkovini ali katero koli pomožno snov, navedeno v poglavju 6.1 ali na druge sulfonamidne snovi;
English: The combination of these substances with complementary mechanisms of action provides an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone.
Slovenian: Kombinacija teh dveh snovi s komplementarnimi mehanizmi delovanja omogoča aditiven antihipertenzivni učinek, ki zniža krvni tlak v večji meri kot vsaka od posameznih učinkovin samostojno.
English: Exposure to aliskiren increased slightly more than in proportion to the increase in dose.
Slovenian: Izpostavljenost aliskirenu je naraščala nekoliko bolj kot sorazmerno z višanjem odmerka.
English: This helps to lower high blood pressure in adult patients.
Slovenian: To pomaga zniževati visok krvni tlak pri odraslih bolnikih.
English: It is also better to avoid this medicine in early pregnancy - see section ‘Pregnancy'.
Slovenian: Temu zdravilu se je bolje izogibati tudi v zgodnji nosečnostiglejte poglavje »Nosečnost«.
English: The frequency, type and severity of adverse reactions in children were generally similar to those seen in hypertensive adults.
Slovenian: Pogostnost, vrsta in izraženost neželenih učinkov pri otrocih so bile večinoma podobne tistim, ki so jih opažali pri odraslih s hipertenzijo.
English: Overall, the mean age of the patients was 11.8 years with 48.6% of patients being in the 6-11 years age group and 51.4% in the 12-17 years age group.
Slovenian: Povprečna starost vseh bolnikov je bila 11,8 let, pri čemer je bilo 48,6 % bolikov v starostni skupini 6-11 let in 51,4 % v starostni skupini 12-17.
English: Other antihypertensive medicinal products
Slovenian: Druga antihipertenzivna zdravila
English: • Red skin (erythema)
Slovenian: • rdečina (eritem)
English: The European Medicines Agency has waived the obligation to submit results of studies with Rasilez HCT in all subsets of the paediatric population in essential hypertension (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Rasilez HCT za vse podskupine pediatrične populacije pri esencialni hipertenziji (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: The antihypertensive effect of a single dose of the combination persisted for 24 hours.
Slovenian: Antihipertenzivno delovanje enkratnega odmerka kombinacije zdravil je trajalo 24 ur.
English: Both of these active substances help to control high blood pressure (hypertension).
Slovenian: Obe učinkovini pomagata uravnavati visok krvni tlak (hipertenzijo).
English: If you take more Rasilez HCT than you should If you have accidentally taken too many tablets of this medicine, talk to a doctor immediately.
Slovenian: Če ste vzeli večji odmerek zdravila Rasilez HCT, kot bi smeli Če ste pomotoma vzeli več tablet tega zdravila, kot bi smeli, se takoj posvetujte z zdravnikom.
English: Do not take this medicine if you are pregnant (see section ‘Do not take Rasilez HCT').
Slovenian: Če ste noseči, ne jemljite tega zdravila (glejte poglavje »Ne jemljite zdravila Rasilez HCT«).
English: The effect of food on hydrochlorothiazide absorption, if any, has little clinical significance.
Slovenian: Vpliv hrane na absorpcijo hidroklorotiazida, če do njega pride, ima le majhen klinični pomen .
English: Treatment effects were similar in patients with diabetes and with renal insufficiency.
Slovenian: Učinki zdravljenja so bili podobni pri bolnikih s sladkorno boleznijo in pri tistih z ledvično insuficienco.
English: Chloride deficit is generally mild and usually does not require treatment.
Slovenian: Pomanjkanje kloridov je večinoma blago in zaradi njega običajno ni potrebno zdravljenje.
English: Side effects associated with each individual component cannot be excluded.
Slovenian: Neželenih učinkov, ki so povezani s posameznimi učinkovinami, ni mogoče izključiti.
English: The absorption of hydrochlorothiazide, after an oral dose, is rapid (Tmax about 2 h).
Slovenian: Absorpcija hidroklorotiazida po zaužitju je hitra (Tmax približno 2 uri).
English: Rasilez HCT may have been prescribed to you because your previous treatment with a medicine containing one of the active components of Rasilez HCT did not lower your blood pressure enough.
Slovenian: Zdravilo Rasilez HCT so vam morda predpisali zato, ker vaše predhodno zdravljenje z zdravilom, ki je vsebovalo samo eno od učinkovin zdravila Rasilez HCT, ni dovolj znižalo krvnega tlaka.
English: The starting dose in each group was assigned depending on weight with three groups: ≥20 to <50 kg, ≥50 to <80 kg, and ≥80 to ≤150 kg.
Slovenian: Začetni odmerek v vsaki skupini je bil določen glede na telesno maso, in sicer v treh skupinah: ≥ 20 do < 50 kg, ≥ 50 do < 80 kg in ≥ 80 do ≤ 150 kg.
English: The available clinical data do not suggest an additive effect of different types of foods and/or drinks, however the potential for decreased aliskiren bioavailability due to this additive effect has not been studied and therefore cannot be excluded.
Slovenian: Razpoložljivi klinični podatki ne kažejo, da bi imelo uživanje raznih vrst hrane in/ali pijače pri tem aditiven učinek, vendar možnosti zmanjšane biološke uporabnosti aliskirena zaradi navedenega aditivnega učinka niso proučevali in je zato ni mogoče izključiti.
English: • Skin rash (this may also be a sign of allergic reactions or angioedema - see “Rare” side effects below)
Slovenian: • kožni izpuščaj (to je lahko tudi znak alergijskih reakcij ali angioedema - glejte "Redki" neželeni učinki, spodaj),
English: This medicine must not be used in babies from birth to less than 2 years of age.
Slovenian: To zdravilo se ne sme uporabljati pri dojenčkih pred dopolnjenim 2. letom starosti.
English: Over 3,900 hypertensive patients received Rasilez HCT once daily in clinical study.
Slovenian: V klinični študiji je več kot 3.900 hipertenzivnih bolnikov prejemalo zdravilo Rasilez HCT enkrat dnevno.
English: The primary endpoint was cardiovascular death or heart failure rehospitalisation within 6 months; secondary endpoints were assessed within 12 months.
Slovenian: Primarni cilj opazovanja je bila kardiovaskularna smrt ali ponovna hospitalizacija zaradi srčnega popuščanja v roku 6 mesecev; sekundarne cilje opazovanja pa so ocenjevali v obdobju 12 mesecev.
English: No specific clinical studies have been performed with this combination, therefore Rasilez HCT should not be used during the first trimester of pregnancy or in women planning to become pregnant and is contraindicated during the second and third trimesters (see section 4.3).
Slovenian: S to kombinacijo niso opravili posebnih kliničnih študij, zato zdravila Rasilez HCT ne smete uporabljati v prvem trimesečju nosečnosti oziroma pri ženskah, ki načrtujejo nosečnost, poleg tega je kontraindiciran v drugem in tretjem trimesečju nosečnosti (glejte poglavje 4.3).
English: Some side effects can be serious: A few patients have experienced these serious side effects.
Slovenian: Nekateri neželeni učinki so lahko resni: Do teh resnih neželenih učinkov je prišlo le pri majhnem številu bolnikov.
English: Although meals (low or high fat content) have been shown to reduce the absorption of aliskiren substantially, the efficacy of aliskiren was shown to be similar when taken either with a light meal or without a meal (see section 4.2).
Slovenian: Kljub temu, da se je pokazalo, da obroki (z veliko ali z majhno vsebnostjo maščob) bistveno zmanjšajo absorpcijo aliskirena, se je izkazalo, da je učinkovitost aliskirena podobna, če se ga jemlje z lahkim obrokom ali brez (glejte poglavje 4.2).
English: It reduces the amount of angiotensin II the body can make.
Slovenian: Zmanjšuje količino angiotenzina II, ki nastaja v telesu.
English: Hepatic MDR1 mRNA expression was statistically significantly lower in samples from foetuses, neonates and infants up to 23 months.
Slovenian: Izražanje mRNA prenašalca MDR1 je bilo statistično značilno manjše v vzorcih plodov, novorojenčkov in malčkov v starosti do 23 mesecev.
English: The safety of the combination therapy was similar to the respective monotherapies regardless of severity of hypertension or of the presence or absence of additional cardiovascular risk.
Slovenian: Varnost kombiniranega zdravila je bila podobna kot pri uporabi posameznih monoterapij ne glede na izraženost hipertenzije ali na prisotnost ali odsotnost kardiovaskularnih tveganj.
English: • Bruising and frequent infections (aplastic anaemia)
Slovenian: • podplutbe in pogoste okužbe (aplastična anemija),
English: It is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Slovenian: Jemanje med nosečnostjo ni priporočljivo, ko pa ste noseči več kot 3 mesece, ga ne smete jemati, ker lahko uporaba po tretjem mesecu nosečnosti povzroči resno škodo vašemu otroku.
English: Mean weight was 68.0 kg with 57.7% of patients having BMI greater than or equal to the 95th percentile for age and gender.
Slovenian: Povprečna telesna masa je bila 68,0 kg, pri čemer je 57,7 % bolnikov imelo ITM večji ali enak kot 95. percentil za starost in spol.
English: If any of the above applies to you, do not take Rasilez HCT and talk to your doctor.
Slovenian: Če kaj od navedenega velja za vas, ne jemljite zdravila Rasilez HCT in se posvetujte s svojim zdravnikom.
English: Mechanisms responsible for the deviation from dose proportionality have not been identified.
Slovenian: Mehanizmov, ki povzročajo odstopanje od sorazmernosti z višino odmerka, še niso pojasnili.
English: This medicine is used to treat high blood pressure in adult patients.
Slovenian: To zdravilo je namenjeno zdravljenju visokega krvnega tlaka pri odraslih bolnikih.
English: Patients should establish a convenient daily schedule of medicinal product intake and maintain a steady temporal relationship with food intake.
Slovenian: Bolniki naj vzpostavijo primeren dnevni razpored vnosa zdravila in vzdržujejo stalno časovno razmerje med jemanjem zdravila in obroki.
English: Non-depolarising skeletal muscle relaxants
Slovenian: Nedepolarizacijski relaksanti skeletnih mišic
English: In addition, due to the possibility of up-titration if medically necessary to control the msSBP, no conclusion can be drawn on the appropriate posology of aliskiren in patients aged 6 to 17 years.
Slovenian: Poleg tega zaradi možnosti titriranja odmerka navzgor, če je bilo to medicinsko potrebno za nadzorovanje povprečnega sistoličnega krvnega tlaka sede, ni mogoče izpeljati nobene ugotovitve/sklepa o primernem odmerjanju aliskirena pri bolnikih, starih od 6 do 17 let.
English: Therefore, aliskiren is not expected to affect the systemic exposure of substances that inhibit, induce or are metabolised by these enzymes.
Slovenian: Zato ni pričakovati, da bi aliskiren vplival na sistemsko izpostavljenost učinkovinam, ki zavirajo ali inducirajo te encime oziroma so njihovi substrati.
English: Rasilez HCT contains lactose and wheat starch (containing gluten) This medicine contains lactose (milk sugar).
Slovenian: Zdravilo Rasilez HCT vsebuje laktozo in pšenični škrob (ki vsebuje gluten) To zdravilo vsebuje laktozo (mlečni sladkor).
English: Rasilez HCT has minor influence on the ability to drive and use machines.
Slovenian: Zdravilo Rasilez HTC ima blag vpliv na sposobnost vožnje in upravljanja strojev.
English: Via Provinciale Schito 131 IT-80058 Torre Annunziata/NA Italy
Slovenian: Via Provinciale Schito 131 IT-80058 Torre Annunziata/NA Italija
English: There was no evidence that this finding was enhanced in the aliskiren/hydrochlorothiazide combination as it was only apparent at a minimal severity in all animals.
Slovenian: Nič ne kaže, da bi do teh opažanj prihajalo pogosteje pri uporabi kombinacije aliskiren/hidroklorotiazid, saj je bil pojav pri vseh živalih le minimalno izražen.
English: • Liver disorders which can occur together with yellow skin and eyes
Slovenian: • bolezni jeter, ki jih lahko spremljajo rumena koža in oči,
English: Digoxine or other digitalis glycosides
Slovenian: Digoksin ali ostali digitalisovi glikozidi
English: You should establish a convenient daily schedule to take the medicine the same way each day, in a regular pattern with respect to the timing of your meals.
Slovenian: Vzpostavite primeren dnevni razpored, da bi lahko vzeli zdravilo vsak dan enako, v ustaljenih vzorcih glede na čas obrokov.
English: Pharmacotherapeutic group: Agents acting on the renin-angiotensin system; renin inhibitor, ATC code: C09XA52
Slovenian: Farmakoterapevtska skupina: zdravila z delovanjem na renin-angiotenzinski sistem, zaviralci renina, oznaka ATC: C09XA52
English: • Severe skin reactions (toxic epidermal necrolysis and/or oral mucosal reactions - red skin,
Slovenian: • hude kožne reakcije (toksična epidermalna nekroliza in/ali reakcije ustne sluznice - rdeča koža,
English: • Nausea, loss of appetite, dark coloured urine or yellowing of skin and eyes (signs of liver disorder) (frequency not known: frequency cannot be estimated from the available data).
Slovenian: • siljenje na bruhanje, izguba apetita, temno obarvan urin ali porumenevanje kože in oči (znaki bolezni jeter) (pogostnost neznana: pogostnosti ni mogoče oceniti iz razpoložljivih podatkov).
English: Dosing should be individualised and adjusted according to the patient's clinical response.
Slovenian: Odmerek je treba prilagajati posameznemu bolniku glede na njegov klinični odziv.
English: Findings during repeat-dose toxicity studies in animals were consistent with the known local (gastrointestinal tract) irritation potential or the expected pharmacological effects of aliskiren.
Slovenian: Rezultati toksikoloških študij ponavljajočih se odmerkov na živalih so bili skladni z znano možnostjo lokalnega draženja (v gastrointestinalnem traktu) ali s pričakovanimi farmakološkimi učinki aliskirena.
English: The treatment with aliskiren was well tolerated in this study.
Slovenian: V tej študiji so bolniki aliskiren dobro prenašali.
English: • Low blood pressure
Slovenian: • nizek krvni tlak,
English: The study also evaluated the combination of aliskiren and enalapril.
Slovenian: V študiji so vrednotili tudi uporabo kombinacije aliskirena in enalaprila.
English: See also section “Do not take Rasilez HCT”.
Slovenian: Glejte tudi poglavje “Ne jemljite zdravila Rasilez HCT”.
English: The systemic exposure to aliskiren in 8-day old rats was >400-fold higher than in adult rats.
Slovenian: Sistemska izpostavljenost aliskirenu je bila pri 8 dni starih podganah več kot 400-krat večja kot pri odraslih podganah.
English: Therefore, dialysis is not adequate to treat aliskiren over-exposure.
Slovenian: Dializa torej ne zadošča za odpravljanje prevelike izpostavljenosti aliskirenu.
English: However the efficacy of aliskiren was similar when taken with a light meal or under fasted state.
Slovenian: Učinkovitost aliskirena je podobna v primeru, ko se ga jemlje z lahkimi obroki, ali na tešče.
English: Vitamin D and calcium salts
Slovenian: Vitamin D in kalcijeve soli
English: Results from a mechanistic study showed that the MDR1 (P-gp) gene expression in juvenile rats was significantly lower when compared to adult rats.
Slovenian: Rezultati mehanističnih študij so pokazali, da je obseg izražanja gena MDR1 (P-gp) pri podganjih mladičih statistično značilno manjši kot pri odraslih podganah.
English: Not recommended (see section 4.2)
Slovenian: Zdravila, ki se jih ne priporoča (glejte poglavje 4.2)
English: There is no evidence that Rasilez HCT would reduce or prevent diuretic-induced hyponatraemia.
Slovenian: Ni dokazov, da bi zdravilo Rasilez HCT zmanjševalo ali preprečevalo hiponatriemijo, ki jo sicer povzročajo diuretiki.
English: If this is the case, your doctor will tell you how to switch from that treatment to Rasilez HCT.
Slovenian: V tem primeru vam bo zdravnik povedal, kako preiti s predhodnega zdravljenja na uporabo zdravila Rasilez HCT.
English: This medicine contains two active substances, called aliskiren and hydrochlorothiazide.
Slovenian: To zdravilo vsebuje dve učinkovini, imenovani aliskiren in hidroklorotiazid.
English: • Decrease in vision or pain in your eyes due to high pressure (possible signs of acute-angle closure glaucoma)
Slovenian: • poslabšanje vida ali bolečina v očeh zaradi visokega očesnega tlaka (možni znaki akutnega glavkoma zaprtega zakotja),
English: In addition, an increased incidence of adverse events was observed with aliskiren compared to placebo (38.2% versus 30.3%).
Slovenian: Poleg tega so pri uporabi aliskirena v primerjavi s placebom opažali povečano pogostnost neželenih dogodkov (38,2 % v primerjavi s 30,3 %).
English: Safety pharmacology studies with aliskiren did not reveal any adverse effects on central nervous, respiratory or cardiovascular function.
Slovenian: Farmakološke študije varnosti aliskirena niso razkrile nobenega neželenega učinka na centralno živčevje, dihanje in delovanje srčnožilnega sistema.
English: A switch to a suitable alternative treatment should be carried out in advance of a planned pregnancy.
Slovenian: Pred načrtovanjem nosečnosti je treba preiti na ustrezno alternativno zdravljenje.
English: It is especially important to tell your doctor if you are using the following medicines: - lithium (a medicine used to treat some types of depression).
Slovenian: Posebno pomembno je, da zdravniku poveste, če jemljete naslednja zdravila: - litij (zdravilo, ki se uporablja za zdravljenje nekaterih vrst depresij), - zdravila ali snovi, ki zvečajo količino kalija v krvi.
English: For adverse reactions observed with more than one component of a fixed-dose combination, the highest frequency is listed in the table below.
Slovenian: Za neželene učinke, ki so jih opažali pri več kot eni učinkovini že pripravljene kombinacije zdravila, je v spodnji preglednici navedena najvišja pogostnost.
English: The age at which the transporter system is mature cannot be determined.
Slovenian: Ni mogoče določiti, pri kateri starosti je prenašalni sistem zrel.
English: When driving vehicles or using machines, it must be borne in mind that dizziness or drowsiness may occasionally occur when taking Rasilez HCT.
Slovenian: Pri vožnji motornih vozil in uporabi strojev je treba upoštevati, da lahko med jemanjem zdravila Rasilez HCT občasno pride do omotičnosti ali dremavosti.
English: Warnings and precautions Talk to your doctor before taking Rasilez HCT: - if you have had skin cancer or if you develop an unexpected skin lesion during the treatment.
Slovenian: Pred začetkom jemanja zdravila Rasilez HCT se posvetujte z zdravnikom: - če ste imeli kožnega raka ali če se vam med zdravljenjem pojavijo nepričakovane kožne spremembe.
English: The starting doses for aliskiren were 37.5/75/150 mg in the low, mid and high weight groups, respectively.
Slovenian: Začetni odmerki aliskirena so bili 37,5/75/150 mg v skupinah z nizko, srednjo in visoko telesno maso.
English: • Severely decreased urine output (possible signs of renal disorder or renal failure), weakness
Slovenian: • zelo zmanjšano izločanje urina (možni znaki ledvične bolezni ali odpovedi ledvic), šibkost
English: Caution required with concomitant use
Slovenian: Zdravila, pri katerih je potrebna previdnost pri sočasni uporabi
English: Wheat starch in this medicine contains only very low levels of gluten (less than 100ppm) and is very unlikely to cause problems if you have coeliac disease.
Slovenian: Pšenični škrob v tem zdravilu vsebuje le zelo majhne količine glutena (manj kot 100 ppm) in je zelo verjetno, da vam ne bo povzročil težav, če imate celiakijo.
English: The risk of hypokalaemia is greater in patients with cirrhosis of the liver, patients experiencing brisk diuresis, patients with inadequate oral electrolyte intake and patients receiving concomitant therapy with corticosteroids or adrenocorticotropic hormone (ACTH) (see sections 4.5 and 4.8).
Slovenian: Tveganje za hipokaliemijo je večje pri bolnikih s cirozo jeter, pri bolnikih, pri katerih pride do obilnega izločanja urina, pri bolnikih, ki ne zaužijejo dovolj elektrolitov, in pri bolnikih, ki sočasno prejemajo kortikosteroide ali kortikotropin (ACTH) (glejte poglavji 4.5 in 4.8).
English: Upon withdrawal of the aliskiren treatment (aliskiren with or without hydrochlorothiazide add-on), the return of blood pressure towards baseline was gradual (3-4 weeks) with no evidence of the rebound effect.
Slovenian: Po prenehanju zdravljenja z aliskirenom (z dodanim hidroklorotiazidom ali brez njega) se je krvni tlak (v 3-4 tednih) postopoma vrnil na izhodiščne vrednosti, pri tem ni bilo nobenih znakov za povratni učinek.
English: − Hereditary or idiopathic angioedema.
Slovenian: − dedni ali idiopatski angioedem;
English: Aliskiren should be used with caution in patients with serious congestive heart failure (New York Heart Association (NYHA) functional class III-IV) (see section 5.1).
Slovenian: Previdnost je potrebna pri uporabi aliskirena pri bolnikih z resnim kongestivnim srčnim popuščanjem (funkcijskih razredov III-IV po klasifikaciji Newyorškega združenja za srce (New York Heart Association (NYHA)) (glejte poglavje 5.1).
English: The starting doses for enalapril were 2.5/5/10 mg in the low, mid and high weight groups, respectively.
Slovenian: Začetni odmerki enalaprila so bili 2,5/5/10 mg v skupinah z nizko, srednjo in visoko telesno maso.
English: Name and address of the manufacturer(s) responsible for batch release Noden Pharma DAC
Slovenian: Ime in naslov izdelovalca (izdelovalcev), odgovornega za sproščanje serij Noden Pharma DAC
English: The usual dose of Rasilez HCT is one tablet a day.
Slovenian: Običajni odmerek zdravila Rasilez HCT je ena tableta na dan.
English: The incidence of atrial fibrillation was 11.1%, 13.3%, and 11.0% in the combination, aliskiren, and enalapril groups, respectively.
Slovenian: Pogostnost atrijske fibrilacije je bila 11,1 %, 13,3 % oziroma 11,0 % v skupini s kombinacijo oziroma skupinah samo z aliskirenom oziroma samo z enalaprilom.
English: • Kidney problems including acute renal failure (severely decreased urine output)
Slovenian: • težave z ledvicami, vključno z akutno ledvično odpovedjo (zelo zmanjšanim nastajanjem urina),
English: The safety and efficacy of aliskiren in children aged 6 to 17 years have not yet been established.
Slovenian: Varnost in učinkovitost aliskirena pri otrocih, starih od 6 do 17 let, še nista bili dokazani.
English: However, in the subsequent 4 week randomised withdrawal phase of the study (Phase 2), the effect of aliskiren overlapped with the effects observed in patients switched to placebo in all dose groups (low, p=0.8894; mid, p=0.9511; high, p=0.0563).
Slovenian: tedenski randomizirani fazi študije z umikom zdravila (2. faza) učinek aliskirena v vseh odmernihskupinah prekrival z učinki, ki so jih opazili pri bolnikih, ki so prešli na placebo (nizek odmerek, p = 0,8894; srednji odmerek, p = 0,9511; visok odmerek, p = 0,0563).
English: − Children from birth to less than 2 years (see sections 4.2 and 5.3).
Slovenian: − otroci pred dopolnjenim 2. letom starosti (glejte poglavji 4.2 in 5.3).
English: However, since aliskiren has been shown to be a substrate for the organic anion-transporting polypeptide 1A2 (OATP1A2) (see section ‘Organic anion transporting polypeptide (OATP' below) inhibitors), there is a potential for aliskiren to reduce plasma torasemide exposure by an interference with the absorption process.
Slovenian: Ker pa so dokazali, da je aliskiren substrat polipeptidnega prenašalca organskih anionov 1A2 (OATP1A2) (glejte poglavje »Zaviralci polipeptidnega prenašalca organskih anionov« spodaj), obstaja možnost, da aliskiren z oviranjem procesa absorpcije znižuje izpostavljenost torasemidu v plazmi.
English: • Increased liver enzymes
Slovenian: • zvišane vrednosti jetrnih encimov.
English: You may need to stop Rasilez HCT.
Slovenian: Morda boste morali prenehati z jemanjem zdravila Rasilez HCT.
English: Aliskiren/hydrochlorothiazide
Slovenian: Aliskiren/hidroklorotiazid