FrancophonIA/ELRC3.0 huggingface dataset:
English: T uberculosis, opportunistic infection (including invasive fungal, protozoal, bacterial, atypical mycobacterial, viral infections, and Legionella)*
Croatian: Tuberkuloza, oportunistička infekcija (uključujući invazivne gljivične, protozoalne, bakterijske, atipične mikobakterijske, virusne infekcije i Legionellu)*
English: These mean concentrations were similar to those seen in adult patients with plaque psoriasis treated with 25 mg etanercept twice weekly.
Croatian: Te prosječne koncentracije bile su slične onima zabilježenim u odraslih bolesnika s plak psorijazom liječenih s 25 mg etanercepta dva puta tjedno.
English: To help you remember, it may be helpful to write in a diary which day(s) of the week Enbrel should be used.
Croatian: Radi lakšeg pamćenja, može Vam pomoći vođenje dnevnika i bilježenje dana kada trebate primijeniti Enbrel.
English: Keep the pre-filled pens in the outer carton in order to protect from light.
Croatian: Napunjene brizgalice čuvati u vanjskom pakiranju, radi zaštite od svjetlosti.
English: In plaque psoriasis, infiltration by inflammatory cells including T-cells leads to increased TNF levels in psoriatic lesions compared with levels in uninvolved skin.
Croatian: Kod plak psorijaze infiltracija upalnim stanicama uključujući T stanice vodi do porasta razine TNF-a u psorijatičnim lezijama u usporedbi s razinama istih u koži koja nije promijenjena.
English: The safety and efficacy of Enbrel in patients with immunosuppression have not been evaluated.
Croatian: Sigurnost primjene i djelotvornost Enbrela u bolesnika s imunosupresijom nisu ispitane.
English: There were no differences in rates of infection among patients treated with Enbrel and those treated with placebo for plaque psoriasis in placebo-controlled trials of up to 24 weeks duration.
Croatian: Kod liječenja plak psorijaze nisu zabilježene razlike u stopi infekcija između bolesnika liječenih Enbrelom i onih koji su primali placebo u placebom kontroliranim ispitivanjima u trajanju do 24 tjedna.
English: In part 1, all patients received 0.4 mg/kg (maximum 25 mg per dose) Enbrel subcutaneously twice weekly.
Croatian: U prvom dijelu ispitivanja svi su bolesnici primili 0,4 mg/kg (najviše 25 mg po dozi) Enbrela supkutano dva puta tjedno.
English: Your doctor may decide if you or the child need less anti-diabetic medicine while taking Enbrel.
Croatian: Liječnik može odlučiti trebate li Vi ili dijete za vrijeme liječenja Enbrelom uzimati manju količinu antidijabetičkog lijeka.
English: TNF-antagonist therapy are not available.
Croatian: om kombinacijom antiviralne terapije i antagonista TNF-a nisu dostupni.
English: Based on pharmacokinetic data (see section 5.2), no dose adjustment is needed in patients with renal or hepatic impairment; clinical experience in such patients is limited.
Croatian: Temeljem farmakokinetičkih podataka (vidjeti dio 5.2) u liječenju bolesnika s oštećenjem bubrega ili jetre nije potrebna prilagodba doza.
English: There is no known antidote to Enbrel.
Croatian: Antidot za Enbrel nije poznat.
English: Patients also had plaque psoriasis with a qualifying target lesion ≥ 2 cm in diameter.
Croatian: Bolesnici su također trebali imati plak psorijazu s kožnim promjenama promjera > 2 cm.
English: Keep the pre-filled syringes in the outer carton in order to protect from light.
Croatian: Napunjene štrcaljke čuvati u vanjskom pakiranju, radi zaštite od svjetlosti.
English: The active substance in Enbrel is etanercept.
Croatian: Djelatna tvar Enbrela je etanercept.
English: A higher rate of major birth defects was observed in one observational study comparing pregnancies exposed to etanercept (n=370) during the first trimester with pregnancies not exposed to etanercept or other TNF-antagonists (n=164) (adjusted odds ratio 2.4, 95% CI: 1.0-5.5).
Croatian: U jednom opservacijskom ispitivanju koje je uspoređivalo trudnoće koje su bile izložene etanerceptu (n=370) tijekom prvog tromjesečja sa trudnoćama koje nisu bile izložene etanerceptu ili drugim antagonistima TNF-a (n=164), zabilježena je viša stopa velikih urođenih mana (prilagođen omjer izgleda 2,4; 95% CI: 1,0-5,5).
English: In a clinical study of adult patients who were receiving established doses of sulfasalazine, to which Enbrel was added, patients in the combination group experienced a statistically significant decrease in mean white blood cell counts in comparison to groups treated with Enbrel or sulfasalazine alone.
Croatian: U kliničkom ispitivanju u odraslih bolesnika koji su primali uobičajene doze sulfasalazina, kojima je dodan Enbrel, bolesnici u skupini s ovom kombinacijom imali su statistički značajan pad prosječnog broja broja leukocita u usporedbi sa skupinama koje su liječene samo Enbrelom ili samo sulfasalazinom.
English: In study 3, the majority of patients (77%) who were initially randomised to 50 mg twice weekly and had their Enbrel dose decreased at week 12 to 25 mg twice weekly maintained their PASI 75 response through week 36.
Croatian: U ispitivanju 3 u većine bolesnika (77%) koji su na početku randomizirani u skupinu koja je dobivala Enbrel u dozi od 50 mg dvaput tjedno pa je njihova doza Enbrela snižena nakon 12 tjedna na 25 mg dvaput tjedno odgovor PASI 75 održan je do kraja 36. tjedna.
English: (n = 231) a: Patients who did not complete 12 months in the study were considered to be non-responders.
Croatian: Enbrel + Metotreksat (n = 231) a: Za bolesnike koji nisu završili 12 mjeseci u ispitivanju smatralo se da nisu odgovorili na terapiju.
English: ASAS 20 2 weeks
Croatian: ASAS 20 2 tjedna 3 mjeseca 6 mjeseci
English: Various malignancies have also been reported with use of Enbrel, including cancers of the breast, lung, skin and lymph glands (lymphoma).
Croatian: Za vrijeme primjene Enbrela također su prijavljeni slučajevi raznih zloćudnih bolesti uključujući rak dojke, pluća, kože i limfnih žlijezda (limfomi).
English: During a randomised withdrawal period, significantly more patients re-randomised to placebo experienced disease relapse (loss of PASI 75 response) compared with patients re-randomised to Enbrel.
Croatian: Tijekom randomiziranog razdoblja prekida terapije, značajno više bolesnika koji su ponovno randomizirani u skupinu s placebom ušlo je u recidiv bolesti (gubitak odgovora PASI 75) u usporedbi s bolesnicima koji su ponovno randomizirani u skupinu s Enbrelom.
English: Enbrel is available in strengths of 10, 25 and 50 mg.
Croatian: Enbrel je dostupan u jačinama od 10, 25 i 50 mg.
English: • Signs of lupus or lupus-like syndrome, such as weight changes, persistent rash, fever, joint or muscle pain, or fatigue
Croatian: • Znakovi lupusa ili sindroma nalik lupusu, kao što su promjene tjelesne težine, uporan kašalj, vrućica, bol u zglobovima ili mišićima ili umor
English: The following instructions explain how to prepare and inject Enbrel.
Croatian: Slijedeće upute objašnjavaju način pripreme i primjene injekcija Enbrela.
English: Date of first authorisation: 03 February 2000 Date of last renewal: 03 February 2010
Croatian: Datum prvog odobrenja: 03. veljače 2000.
English: The safety and efficacy profiles of the 50 mg once weekly and 25 mg twice weekly regimens were similar.
Croatian: Profili sigurnosti primjene i djelotvornosti 50 mg jednom tjedno i 25 mg dva puta tjedno režima bili su slični.
English: Concurrent administration of Enbrel and anakinra has been associated with an increased risk of serious infections and neutropenia compared to Enbrel alone.
Croatian: Istodobno davanje Enbrela i anakinre povezano je s povećanim rizikom od ozbiljnih infekcija i neutropenije u usporedbi s monoterapijom Enbrelom.
English: How to store Enbrel
Croatian: Kako primjenjivati Enbrel
English: Study 1 was a Phase 2 study in patients with active but clinically stable plaque psoriasis involving ≥ 10% of the body surface area that were ≥ 18 years old.
Croatian: Ispitivanje 1 je bilo ispitivanje faze II u koje su uključeni bolesnici s aktivnom, ali klinički stabilnom plak psorijazom koja zahvaća ≥10% površine tijela u dobi
English: Before injection, Enbrel single-use pre-filled syringe should be allowed to reach room temperature (approximately 15 to 30 minutes).
Croatian: Prije injekcije: Enbrel napunjena brizgalica za jednokratnu uporabu treba se ostaviti na sobnoj temperaturi (približno 15 do 30 minuta).
English: However, the solution may be used for up to 6 hours when stored at a temperature up to 25°C.
Croatian: Međutim, otopina se može primijeniti i do 6 sati po pripremi, kada je čuvana na temperaturi do 25°C.
English: • Trouble swallowing or breathing
Croatian: • Tegobe s gutanjem ili disanjem,
English: Enbrel has been shown to improve physical function in patients with psoriatic arthritis, and to reduce the rate of progression of peripheral joint damage as measured by X-ray in patients with polyarticular symmetrical subtypes of the disease.
Croatian: Pokazalo se da Enbrel dovodi do poboljšanja fizičke funkcije u bolesnika s psorijatičnim artritisom te da smanjuje brzinu napredovanja oštećenja perifernih zglobova određenu pomoću rendgena u bolesnika s poliartikularnom simetričnom podvrstom bolesti.
English: In one study in children with juvenile idiopathic arthritis aged 4 to 17 years, 43 of 69 (62%) children experienced an infection while receiving Enbrel during 3 months of the study (part 1, open-label), and the frequency and severity of infections was similar in 58 patients completing 12 months of open-label extension therapy.
Croatian: U jednom ispitivanju u pedijatrijskih bolesnika s juvenilnim idiopatskim artritisom u dobi od 4 do 17 godina, 43 od 69 (62%) djece imalo je infekciju tijekom primanja Enbrela u toku tromjesečnog ispitivanja (prvi dio, otvoreno ispitivanje), a učestalost i težina infekcija bile su slične i u 58 bolesnika koji su završili produljeno liječenje tijekom 12 mjeseci otvorenog ispitivanja.
English: Clinical improvement, including onset of action within 2 weeks with Enbrel 25 mg, was similar to that seen in the previous trials and was maintained for up to 24 months.
Croatian: Kliničko poboljšanje, uključujući početak djelovanja Enbrela u dozi od 25 mg unutar razdoblja od 2 tjedna, bilo je slično onome zabilježenom u prethodnim ispitivanjima te se održalo tijekom sljedeća 24 mjeseca.
English: Instructions for preparing and giving an injection of Enbrel
Croatian: Upute za pripremu i primjenu injekcije Enbrela
English: • Signs of heart failure or worsening heart failure, such as fatigue or shortness of breath with activity, swelling in the ankles, a feeling of fullness in the neck or abdomen, night-time shortness of breath or coughing, bluish colour of the nails or the lips
Croatian: • Znakovi zatajivanja srca ili pogoršanja zatajenja srca, kao što su umor ili nedostatak zraka prilikom aktivnosti, oticanje gležnjeva, osjećaj punoće u vratu ili trbuhu, nedostatak zraka ili kašalj tijekom noći, modra boja noktiju ili usana.
English: • Remove the needle cover by firmly pulling it straight off the syringe taking care not to touch the needle or allow the needle to touch any surfaces (see Diagram 15).
Croatian: • Uklonite poklopac igle tako što ćete ga čvrstim potezom ravno povući sa štrcaljke, pazeći pritom da ne dodirnete iglu i da igla ne dodirne nikakvu dugu površinu (vidjeti sliku 15).
English: In subjects treated with approved doses of etanercept in clinical trials for up to 12 months, cumulative rates of anti-etanercept antibodies were approximately 6% of subjects with rheumatoid arthritis, 7.5% of subjects with psoriatic arthritis, 2% of subjects with ankylosing spondylitis, 7% of subjects with psoriasis, 9.7% of subjects with paediatric psoriasis, and 4.8 % of subjects with juvenile idiopathic arthritis.
Croatian: U bolesnika liječenih odobrenim dozama etanercepta u kliničkim ispitivanjima do 12 mjeseci kumulativne stope protutijela na etanercept bile su otprilike 6% u osoba s reumatoidnim artritisom, 7,5% u osoba s psorijatičnim artritisom, 2% u osoba s ankilozantnim spondilitisom, 7% u osoba s psorijazom, 9,7% u osoba s psorijazom dječje dobi i 3% u osoba s juvenilnim idiopatskim artritisom.
English: A single 50 mg/ml injection of Enbrel was found to be bioequivalent to two simultaneous injections of 25 mg/ml.
Croatian: Pronašlo se da je jednokratna injekcija Enbrela od 50 mg/ml bioekvivalentna dvjema istodobno primijenjenim injekcijama od 25 mg/ml.
English: Contact your doctor before using Enbrel if the needle cover will be handled by, or Enbrel will be given to, someone with a known or possible hypersensitivity (allergy) to latex.
Croatian: Obratite se liječniku prije primjene Enbrela ako će poklopac igle dodirivati ili će se Enbrel davati osobi za koju se zna ili kod koje postoji mogućnost preosjetljivosti (alergije) na lateks.
English: Before injection, Enbrel single-use pre-filled pens should be allowed to reach room temperature (approximately 15 to 30 minutes).
Croatian: Prije injekcije: Enbrel napunjena štrcaljka za jednokratnu uporabu treba se ostaviti na sobnoj temperaturi (približno 15 do 30 minuta).
English: Enbrel did not elicit dose-limiting or target organ toxicity in cynomolgus monkeys following twice weekly subcutaneous administration for 4 or 26 consecutive weeks at a dose (15 mg/kg) that resulted in AUC-based serum drug concentrations that were over 27-fold higher than that obtained in humans at the recommended dose of 25 mg.
Croatian: U Enbrela nije zabilježena toksičnost koja bi ograničavala dozu, kao ni toksičnost prema ciljnim organima prilikom primjene u cinomolgus majmuna u dozi od 15 mg/kg supkutano, dva puta tjedno, tijekom 4 ili 26 uzastopnih tjedana, a pri toj su dozi serumske koncentracije lijeka izmjerene na osnovi AUC bile više od 27 puta veće od one izmjerene u ljudi prilikom primjene preporučene doze od 25 mg.
English: Step 1: Setting up for an injection Step 2: Choosing an injection site Step 3: Injecting the Enbrel solution Step 4: Disposing of supplies
Croatian: Korak 1: Priprema za injekciju Korak 2: Odabir mjesta uboda Korak 3: Ubrizgavanje otopine Enbrela Korak 4: Odlaganje uporabljenog pribora
English: Instead, the safety and efficacy of Enbrel were assessed in four randomised, double-blind, placebo-controlled studies.
Croatian: Umjesto toga djelotvornost i sigurnost primjene Enbrela procjenjivane su u četiri randomizirana, dvostruko slijepa, placebom kontrolirana ispitivanja.
English: The needle cover of the pre-filled syringe contains latex (dry natural rubber) that may cause hypersensitivity reactions when handled by, or when Enbrel is administered to, persons with known or possible latex sensitivity.
Croatian: Poklopac za iglu na napunjenoj brizgalici sadrži lateks (suhu prirodnu gumu) koji može izazvati reakcije preosjetljivosti kad osoba s poznatom ili mogućom osjetljivošću na lateks rukuje brizgalicom ili prima Enbrel.
English: Serious infections experienced by Enbrel-treated patients included cellulitis, gastroenteritis, pneumonia, cholecystitis, osteomyelitis, gastritis, appendicitis, Streptococcal fasciitis, myositis, septic shock, diverticulitis and abscess.
Croatian: U bolesnika liječenih Enbrelom pojavile su se ozbiljne infekcije koje su uključivale celulitis, gastroenteritis, pneumoniju, kolecistitis, osteomijelitis, gastritis, apendicitis, streptokokni fasciitis, miozitis, septični šok, divertikulitis i apsces.
English: In an open-label, safety extension study, 58 paediatric patients from the above study (from the age of 4 years at time of enrolment) continued to receive Enbrel for up to 10 years.
Croatian: U otvorenom produžetku ispitivanja sigurnosti primjene, 58 pedijatrijskih bolesnika iz gore opisanog ispitivanja (u dobi od 4 ili više godina u vrijeme uključenja) nastavilo je primati Enbrel do 10 godina.
English: Again, do not touch the needle or allow it to touch any surface.
Croatian: Opet pazite da ne dodirnete iglu i da igla ne dodirne nijednu površinu.
English: Whilst pushing the pen firmly against the skin to ensure that the needle safety shield is fully depressed inside the pen, press the centre of the green button on top of the pen with your thumb to start the injection (see Diagram 5).
Croatian: Dok čvrsto potiskujete brizgalicu na kožu tako da je sigurnosni štitnik za iglu potpuno potisnut u unutrašnjost brizgalice, palcem pritisnite sredinu zelene tipke na vrhu brizgalice kako bi započelo ubrizgavanje (vidjeti sliku 5).
English: The 10 mg vial is for children prescribed a dose of 10 mg or less.
Croatian: Bočica od 10 mg je za djecu kojoj je propisana doza od 10 mg ili niža.
English: Treatment of active and progressive psoriatic arthritis in adults when the response to previous diseasemodifying antirheumatic drug therapy has been inadequate.
Croatian: Liječenje aktivnog i progresivnog psorijatičnog artritisa u odraslih u slučaju prethodnog neodgovarajućeg odgovora na terapiju antireumatskim lijekovima koji modificiraju tijek bolesti.
English: • Infections/surgery: If you or the child develop a new infection, or are about to have any major surgery, your doctor may wish to monitor the treatment with Enbrel.
Croatian: • Infekcije/operacija: ako Vi ili dijete razvijete novu infekciju ili u slučaju da morate na veliku operaciju, Vaš liječnik će možda htjeti nadgledati liječenje Enbrelom.
English: Do not mix the Enbrel solution with any other medicine.
Croatian: Nemojte miješati otopinu Enbrela niti s jednim drugim lijekom.
English: Gently move the vial in circles a few times, to dissolve the powder (see Diagram 6).
Croatian: Nježno kružnim pokretima zavrtite bočicu nekoliko puta kako bi se prašak otopio (vidjeti sliku 6).
English: Powder: Mannitol, sucrose and trometamol.
Croatian: Prašak: manitol, saharoza i trometamol.
English: 70b a: 25 mg Enbrel SC twice weekly b: p < 0.001, Enbrel vs. placebo c: p < 0.01, Enbrel vs. placebo
Croatian: 6. mjesec a: 25 mg Enbrela supkutano, dva puta tjedno b: p < 0,001, Enbrel u odnosu na placebo c: p < 0,01, Enbrel u odnosu na placebo
English: For polyarthritis or extended oligoarthritis in patients from the age of 2 years, or enthesitis-related arthritis or psoriatic arthritis in patients from the age of 12 years, the usual dose is 0.4 mg of Enbrel per kg bodyweight (up to a maximum of 25 mg) given twice weekly, or 0.8 mg of Enbrel per kg of bodyweight (up to a maximum of 50 mg) given once weekly.
Croatian: Za poliartikularni artritis ili produljeni oligoartritis u bolesnika u dobi od navršene 2 godine ili artritis povezan s entezitisom ili psorijatični artritis u bolesnika u dobi od navršenih 12 godina uobičajena doza je 0,4 mg Enbrela po kg tjelesne težine (do najviše 25 mg) primijenjena dva puta tjedno ili 0,8 mg Enbrela po kg tjelesne težine (do najviše 50 mg) primijenjena jednom tjedno.
English: In adults (aged 18 and over), Enbrel can be used for moderate or severe rheumatoid arthritis, psoriatic arthritis, severe axial spondyloarthritis including ankylosing spondylitis, and moderate or severe psoriasis - in each case usually when other widely used treatments have not worked well enough or are not suitable for you.
Croatian: U odraslih (u dobi od 18 ili više godina) Enbrel se može primijeniti za liječenje umjerenog ili teškog reumatoidnog artritisa, psorijatičnog artritisa, teškog aksijalnog spondiloartritisa uključujući ankilozantni spondilitis i umjerene ili teške psorijaze - u svakom od tih slučajeva, obično kada ostali široko primjenjivani načini liječenja nisu djelovali dovoljno dobro ili su za Vas neprikladni.
English: Your doctor will decide how long you should take Enbrel and whether retreatment is needed based on your response.
Croatian: Na temelju Vašeg odgovora na liječenje liječnik će odlučiti koliko dugo trebate primjenjivati Enbrel i je li potrebno ponoviti liječenje.
English: • Remove the needle cover by firmly pulling it straight off the syringe taking care not to touch the needle or allow the needle to touch any surfaces (see Diagram 1).
Croatian: • Odstranite poklopac igle tako što ćete ga čvrstim pokretom povući ravno sa štrcaljke, pazeći da pritom ne dodirnete iglu i da igla ne dotakne nikakvu drugu površinu (vidjeti sliku 1).
English: At week 12, there was a statistically significant improvement in the SPARCC (Spondyloarthritis Research Consortium of Canada) score for the sacroiliac joint (SIJ) as measured by MRI for patients receiving Enbrel.
Croatian: U 12. tjednu primijećeno je statistički značajno poboljšanje u rezultatu SPARCC-a (Kanadskog istraživačkog konzorcija za spondiloartrtitis) za sakroilijakalni zglob mjereno putem MR-a za bolesnike koji primaju Enbrel.
English: Whilst pushing the pen firmly against the skin to ensure that the needle safety shield is fully depressed inside the pen, press the centre of the grey button on top of the pen with your thumb to start the injection (see Diagram 5).
Croatian: Dok čvrsto potiskujete brizgalicu na kožu tako da je sigurnosni štitnik za iglu potpuno potisnut u unutrašnjost brizgalice, palcem pritisnite sredinu sive tipke na vrhu brizgalice kako bi započelo ubrizgavanje (vidjeti sliku 5).
English: ASAS 50 2 weeks
Croatian: ASAS 50 2 tjedna 3 mjeseca 6 mjeseci
English: There is insufficient evidence of the efficacy of Enbrel in patients with ankylosing spondylitis-like and arthritis mutilans psoriatic arthropathies due to the small number of patients studied.
Croatian: Nema dovoljno dokaza o djelotvornosti Enbrela u bolesnika s psorijatičnim artropatijama koje su slične ankilozantnom spondilitisu i artritis mutilansu, zbog malog broja ispitivanih bolesnika.
English: PASI 50 14 58* 70 74* 77 9 64* 77* 9 69* 83 PASI 75 4 34* 44 49* 59 3 34* 49* 2 38* 71 DSGA b, clear or almost clear *p ≤ 0.0001 compared with placebo a. No statistical comparisons to placebo were made at week 24 in studies 2 and 4 because the original placebo group began receiving Enbrel 25 mg BIW or 50 mg once weekly from week 13 to week 24. b. Dermatologist Static Global Assessment.
Croatian: PASI 50 14 58* 70 74* 77 9 64* 77* 9 69* 83 PASI 75 4 34* 44 49* 59 3 34* 49* 2 38* 71 DSGA
English: Step 3: Injecting the Enbrel solution
Croatian: Korak 3: Ubrizgavanje otopine Enbrela
English: No treatment was given for the majority of injection site reactions in the Enbrel treatment groups, and the majority of patients who were given treatment received topical preparations, such as corticosteroids, or oral antihistamines.
Croatian: U većine bolesnika koji su primali Enbrel i imali reakciju na mjestu primjene injekcije nije provedeno nikakvo liječenje, a većina onih u kojih je provedeno liječenje primila je samo topikalne pripravke, kao što su kortikosteroidi, ili oralne antihistaminike.
English: • Vaccinations: If possible, children should be up to date with all vaccinations before using Enbrel.
Croatian: • Cijepljenje: ako je moguće, u djece bi trebalo obaviti cijepljenje prema trenutno važećem kalendaru cijepljenja, prije nego se započne liječenje Enbrelom.
English: • While still in the plastic package, place the vial adaptor on top of the Enbrel vial so that the vial adaptor spike is centered within the raised circle on top of the vial stopper (see Diagram 2).
Croatian: • Dok je nastavak još u plastičnom pakiranju, postavite ga na vrh bočice Enbrela tako da šiljak nastavka za bočicu bude iznad središta odignutog kruga na gornjoj površini čepa bočice (vidjeti sliku 2).
English: Enbrel, alone or in combination with methotrexate, has been shown to reduce the rate of progression of joint damage as measured by X-ray and to improve physical function.
Croatian: Pokazalo se da Enbrel, kada je primijenjen sam ili u kombinaciji s metotreksatom, usporava progresiju oštećenja zglobova određenu rendgenskim snimanjem, a isto tako poboljšava i fizičku funkciju.
English: Caution should be exercised when administering Enbrel in patients previously infected with HBV.
Croatian: Nužan je oprez u slučaju davanja Enbrela bolesnicima koji su prethodno bili zaraženi HBV-om.
English: Diagram 18
Croatian: Slika 18.
English: Enbrel is reconstituted with 1 ml water for injections before use, and administered by subcutaneous injection.
Croatian: Prije uporabe Enbrel se rekonstituira s 1 ml vode za injekcije i primjenjuje supkutanom injekcijom.
English: • With the needle still inserted in the vial, check the syringe for air bubbles.
Croatian: • Dok je igla još unutar bočice, provjerite da u štrcaljki nema mjehurića zraka.