FrancophonIA/ELRC3.0 huggingface dataset:
English: − Multipacks comprising 3 bottles each containing 30 film-coated tablets (90 tablets)
Croatian: Višestruko pakiranje sadrži 3 boce od kojih svaka sadrži 30 filmom obloženih tableta (90
English: Sorbitan laurate
Croatian: Sorbitanlaurat
English: If this co-administration is judged unavoidable, refer to the abemaciclib SmPC for dosage adjustment recommendations.
Croatian: Ocijeni li se da je ta istodobna primjena neizbježna, potrebno je vidjeti Sažetak opisa svojstava lijeka za abemaciklib za preporuke vezane uz prilagodbu doze.
English: Serum concentrations of ibrutinib may be increased due to CYP3A inhibition by ritonavir, resulting in increased risk for toxicity including risk of tumor lysis syndrome.
Croatian: Serumske se koncentracije ibrutiniba mogu povećati zbog inhibicijskog učinka ritonavira na CYP3A, što može povećati rizik od toksičnosti uključujući rizik od sindroma tumorske lize.
English: In this instance, close clinical monitoring is warranted.
Croatian: tom se slučaju preporučuje pažljivo kliničko praćenje.
English: b. Remove the plunger from the syringe.
Croatian: Izvadite klip iz štrcaljke.
English: How do I take the correct dose of Norvir powder for oral suspension mixed with food (full sachet)?
Croatian: Norvir praška za oralnu suspenziju pomiješanog s hranom (cijela vrećica)?
English: In a study completed in 2000, 76 HIV-1 infected children aged 6 months to 12 years who were protease inhibitor naive and naive to lamivudine and/or stavudine received ritonavir 350 or 450 mg/m2 every 12 hours co-administered with lamivudine and stavudine.
Croatian: U ispitivanju dovršenom 2000. godine, 76 djece u dobi od 6 mjeseci do 12 godina, zaražene virusom HIV-1, koja prethodno nisu primala ni inhibitor proteaza ni lamivudin ni stavudin, dobivalo je ritonavir 350 ili 450 mg/m2 svakih 12 sati istodobno s lamivudinom i stavudinom.
English: ND: Not determined
Croatian: NO: nije određivano
English: What you need to know before you or your child takes Norvir Do not take Norvir
Croatian: Što morate znati prije nego što Vi ili Vaše dijete počnete uzimati Norvir Nemojte uzimati Norvir
English: Across dose groups, ritonavir oral clearance (CL/F/m2) declined with age with median values of 9.0 L/h/m2 in children less than 3 months of age, 7.8 L/h/m2 in children between 3 and 6 months of age and 4.4 L/h/m2 in children between 6 and 24 months of age.
Croatian: Usporedba skupina prema primljenim dozama pokazala je da se klirens oralno primijenjenog ritonavira (CL/F/m2) smanjivao s dobi, te su medijani vrijednosti iznosili 9,0 l/h/m2 u djece mlađe od 3 mjeseca, 7,8 l/h/m2 u djece u dobi od 3 do 6 mjeseci, a 4,4 l/h/m2 u djece u dobi od 6 do 24 mjeseca.
English: Mix the powder and liquid a.Tightly screw on the lid and keep shaking the mixing cup hard for at least 90 seconds until all the lumps have gone.
Croatian: Čvrsto zatvorite poklopac i dobro protresite čašu za miješanje tijekom najmanje 90 sekundi dok se grudice ne otope.
English: Musculosketal and connective tissue disorders
Croatian: Poremećaji mišićno-koštanog sustava i vezivnog tkiva
English: Co-administration of ibrutinib and ritonavir should be avoided.
Croatian: Potrebno je izbjegavati istodobnu primjenu ibrutiniba i ritonavira.
English: Norvir 100 mg powder for oral suspension
Croatian: Norvir 100 mg prašak za oralnu suspenziju
English: Package leaflet: Information for the user Norvir 100 mg film-coated tablets ritonavir
Croatian: Uputa o lijeku: Informacije za korisnika Norvir 100 mg filmom obložene tablete ritonavir
English: Norvir powder for oral suspension comes in individual sachets containing 100 mg ritonavir.
Croatian: Norvir prašak za oralnu suspenziju dolazi u pojedinačnim vrećicama koje sadrže 100 mg ritonavira.
English: Measure the dose a. Check the prescription label on the carton for the dose in ml.
Croatian: Provjerite recept za dozu u mililitrima.
English: (See section 4.
Croatian: (vidjeti dio 4.4).
English: Nevirapine 200 q12h
Croatian: Nevirapin 200 svakih 12h
English: Ritonavir Dosing Regimen
Croatian: Shema doziranja ritonavira
English: Serum concentrations may be increased due to CYP3A inhibition by ritonavir, resulting in increased risk of tumor lysis syndrome at the dose initiation and during the ramp-up phase (see section 4.3 and refer to the venetoclax SmPC).
Croatian: Serumske se koncentracije mogu povećati zbog inhibicijskog učinka ritonavira na CYP3A, što može povećati rizik od sindroma tumorske lize pri uvođenju liječenja i tijekom razdoblja povećavanja doze (vidjeti dio 4.3 i Sažetak opisa svojstava lijeka za venetoklaks).
English: Тел.
Croatian: ART.
English: 350 mg (35.0 ml) twice daily
Croatian: 350 mg (35,0 ml) dva puta na dan
English: No medicinal product interaction study has been performed for the co-administration of Norvir with benzodiazepines.
Croatian: Ispitivanje interakcija pri istodobnoj primjeni lijeka Norvir i benzodiazepina nije provedeno.
English: Common Anorexia, flatulence, mouth ulcer, gastrointestinal haemorrhage, gastroesophageal reflux disease, pancreatitis
Croatian: Često Anoreksija, flatulencija, ulceracija usne šupljine, gastrointestinalno krvarenje, gastroezofagealna refluksna bolest, pankreatitis
English: In a healthy volunteer drug interaction study of delamanid 100 mg twice daily and lopinavir/ritonavir 400/100 mg twice daily for 14 days, the exposure of the delamanid metabolite DM-6705 was 30% increased.
Croatian: U ispitivanju interakcija delamanida u dozi od 100 mg dva puta na dan i lopinavira/ritonavira u dozi od 400/100 mg dva puta na dan tijekom 14 dana kod zdravih dobrovoljaca, izloženost metabolitu delamanida DM-6705 je bila povišena za 30%.
English: Amitriptyline, fluoxetine, imipramine, nortriptyline, paroxetine, sertraline
Croatian: Amitriptilin, fluoksetin, imipramin, nortriptilin, paroksetin, sertralin
English: Clarithromycin doses greater than 1 g per day should not be coadministered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Croatian: Klaritromicin u dozama većima od 1 g na dan ne treba davati istodobno s ritonavirom doziranim kao antiretrovirusnim lijekom ni kao farmakokinetičkim pojačivačem.
English: − Hormonal contraceptives containing ethinyl oestradiol as Norvir may reduce the effectiveness of these medicines.
Croatian: Hormonski kontraceptivi koji sadržavaju etinilestradiol, jer Norvir može smanjiti učinkovitost tih lijekova.
English: • if Norvir is used to boost the effects of certain other anti-HIV medicines the typical dose for adults is 1 to 2 tablets once or twice daily.
Croatian: Preporučene doze lijeka Norvir: • ako se Norvir koristi za pospješenje učinaka drugih lijekova za HIV, uobičajena doza za odrasle je 1 do 2 tablete jedanput ili dva puta na dan.
English: - Hormonal contraceptives containing ethinyl oestradiol as Norvir may reduce the effectiveness of these medicines.
Croatian: − Hormonski kontraceptivi koji sadržavaju etinilestradiol, jer Norvir može smanjiti učinkovitost tih lijekova.
English: even if their signs of illness are the same as yours.
Croatian: Može im naškoditi, čak i ako su njihovi znakove bolesti jednaki Vašima.
English: Ritonavir 100 mg twice daily with saquinavir 1000 mg twice daily provides saquinavir systemic exposure over 24 hours similar to or greater than those achieved with saquinavir 1200 mg three times daily without ritonavir.
Croatian: Ritonavir 100 mg dva puta na dan sa sakvinavirom 1000 mg dva puta na dan osigurava sistemnu izloženost sakvinaviru tijekom 24 sata sličnu ili veću od one koja se postiže sakvinavirom u dozi od 1200 mg triput na dan bez ritonavira.
English: Dose alteration of sulfamethoxazole/trimethoprim during concomitant ritonavir therapy should not be necessary.
Croatian: Mijenjanje doze sulfametoksazola/trimetoprima nije nužno pri njihovoj istodobnoj primjeni s ritonavirom.
English: Concomitant use of ritonavir and fluticasone or other glucocorticoids that are metabolised by CYP3A4 is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression (see section 4.5).
Croatian: Glukokortikoidi Istodobna primjena ritonavira s flutikazonom ili ostalim glukokortikoidima koji se metaboliziraju putem CYP3A4 se ne preporučuje, osim ako očekivana korist od liječenja ne nadmašuje rizik os sistemnih učinaka kortikosteroida, uključujući Cushingov sindrom i supresiju nadbubrežnih žlijezda
English: − Muscle pain, tenderness or weakness, particularly in combination with antiretroviral therapy including protease inhibitors and nucleoside analogues.
Croatian: − Bol, osjetljivost ili slabost mišića, osobito u kombinaciji s uzimanjem antiretrovirusnih lijekova, uključujući inhibitore proteaza i analoge nukleozida.
English: Empty the syringe a. Slowly push the plunger to empty the liquid from the syringe into the mixing cup (see Figure
Croatian: Polako potiskujte klip kako biste ispraznili tekućinu iz štrcaljke u čašu za miješanje
English: − People taking Norvir may still develop infections or other illnesses associated with HIV infection or AIDS.
Croatian: Norvir mogu svejedno razviti infekcije ili druge bolesti povezane s HIVinfekcijom ili s AIDS-om.
English: Concomitant administration of glecaprevir/pibrentasvir and Norvir is not recommended due to an increased risk of ALT elevations associated with increased glecaprevir exposure.
Croatian: Istodobna primjena glekaprevira/pibrentasvira i lijeka Norvir se ne preporučuje zbog povećanog rizika od porasta razine alaninaminotransferaze (ALT) koji je povezan s povećanom izloženošću glekapreviru.
English: Multipack: 90 (3 bottles of 30) film-coated tablets
Croatian: Višestruko pakiranje: 90 (3 boce po 30) filmom obloženih tableta
English: Norvir 100 mg powder for oral suspension ritonavir
Croatian: Norvir 100 mg prašak za oralnu suspenziju ritonavir
English: Patients with advanced HIV disease may be at risk of elevated triglycerides and pancreatitis (see section 4.4).
Croatian: Bolesnici s uznapredovalom HIV bolesti mogu biti izloženi većem riziku od povišenja razine triglicerida i pankreatitisa (vidjeti dio
English: Give the medicine to the patient a. Place the syringe tip against the inside of the patient's cheek.
Croatian: Stavite vrh štrcaljke s unutrašnje strane bolesnikovog obraza.
English: d. Tap the syringe again to break up the bubbles so they are all at the tip (see Figure 9).
Croatian: Ponovo lupkajte štrcaljku kako bi se mjehurići razbili i došli na vrh (pogledajte sliku 9).
English: Delavirdine1
Croatian: Delavirdin1 Ritonavir
English: Pethidine Norpethidine metabolite
Croatian: Petidin Metabolit norpetidin
English: Package leaflet: Information for the user Norvir 100 mg powder for oral suspension ritonavir
Croatian: Uputa o lijeku: Informacije za korisnika Norvir 100 mg prašak za oralnu suspenziju ritonavir
English: − amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, quinidine (used to correct irregular heartbeats);
Croatian: − amiodaron, bepridil, dronedaron, enkainid, flekainid, propafenon, kinidin (koriste se za regulaciju nepravilnih otkucaja srca);
English: A higher frequency of adverse reactions (e.g., dizziness, nausea, paraesthesia) and laboratory abnormalities (elevated liver enzymes) have been observed when efavirenz is co-administered with ritonavir dosed as an antiretroviral agent.
Croatian: Zamijećena je veća učestalost nuspojava (npr. omaglica, mučnina, parestezija) i laboratorijskih poremećaja (porast vrijednosti jetrenih enzima) kada se efavirenz davao istodobno s ritonavirom kao antiretrovirusnim lijekom.
English: Common Decreased white blood cells, decreased haemoglobin, decreased neutrophils, increased eosinophils, thrombocytopenia
Croatian: Često Smanjeni broj leukocita, snižena vrijednost hemoglobina, smanjeni broj neutrofila, povećani broj eozinofila, trombocitopenija
English: − alfuzosin (used to treat enlarged prostate gland);
Croatian: − alfuzosin (koristi se za liječenje povećane prostate);
English: In addition, serum concentrations may be increased when co-administered with ritonavir resulting in the potential for serious adverse events including seizure.
Croatian: Dodatno, serumske se koncentracije mogu povećati pri istodobnoj primjeni ritonavira što može dovesti do potencijalnih ozbiljnih štetnih događaja uključujući napadaj.
English: 176 mg (17.6 ml) twice daily
Croatian: 176 mg (17,6 ml) dva puta na dan
English: Children and adolescents (2 years of age and above) The recommended dosage of Norvir powder for suspension in children is 350 mg/m² by mouth twice daily and should not exceed 600 mg twice daily.
Croatian: Djeca i adolescenti (u dobi od 2 godine i stariji) Preporučena doza Norvir praška za oralnu suspenziju u djece je 350 mg/m2 kroz usta dva puta na dan,
English: Uncommon Myocardial infarction
Croatian: Manje često Infarkt miokarda
English: (If required)
Croatian: (npr. beklometazon).
English: Uncommon Increased neutrophils
Croatian: Manje često Povećani broj neutrofila
English: b. Pour all of the powder into the mixing cup.
Croatian: Isipajte sav prašak iz vrećice u čašu za miješanje.
English: ↑ 2.5 fold
Croatian: ↑ 2,5 puta
English: Administration of a single 100 mg dose of ritonavir powder for oral suspension with a moderate fat meal (617 kcal, 29% calories from fat) was associated with a mean decrease of 23 and 39% in ritonavir AUCinf and Cmax respectively, relative to fasting conditions.
Croatian: Primjena jedne doze od 100 mg ritonavir praška za oralnu suspenziju s obrokom s umjerenim udjelom masti (617 kcal, 29% kalorija iz masti) je bila povezana sa srednjim smanjenjem AUCinf vrijednosti od 23% i Cmax vrijednosti od 39% u odnosu na primjenu natašte.
English: Across dose groups, ritonavir oral clearance (CL/F/m2)
Croatian: Usporedba skupina prema primljenim dozama pokazala je da se klirens oralno primijenjenog ritonavira (CL/F/m2)
English: You must not take Norvir with colchicine if you have kidney and/or liver problems (see also ‘Do not take Norvir' above).
Croatian: Ne smijete uzimati Norvir s kolhicinom ako imate tegobe s bubrezima i/ili jetrom (pogledajte i dio
English: Copovidone
Croatian: Kopovidon
English: Based on cross-study comparison to 1200 mg amprenavir twice daily alone.
Croatian: Zasniva se na usporedbi među ispitivanjima s 1200 mg amprenavira dva puta na dan, u monoterapiji.
English: Based on cross-study comparison to 400 mg atazanavir once daily alone.
Croatian: Zasniva se na usporedbi među ispitivanjima s 400 mg atazanavira jedanput na dan, u monoterapiji.
English: Concomitant use of ritonavir (500 mg twice daily) dosed as an antiretroviral agent and rifabutin due to an increase of rifabutin serum concentrations and risk of adverse events including uveitis (see section 4.4).
Croatian: Pri istodobnoj primjeni ritonavira (500 mg dva puta na dan) doziranog kao antiretrovirusnog lijeka i rifabutina povećavaju se serumske koncentracije rifabutina, a time i rizik od nuspojava, uključujući uveitis (vidjeti dio 4.4).
English: - Rifampicin and saquinavir (used for tuberculosis and HIV, respectively) as serious liver damage can occur when taken with Norvir.
Croatian: − Rifampicin i sakvinavir (prvi se daje za tuberkulozu, drugi za HIV), jer može nastupiti ozbiljno oštećenje jetre kada se ti lijekovi uzimaju s lijekom Norvir.
English: How to store Norvir
Croatian: Kako čuvati Norvir
English: − avanafil or vardenafil (used to treat erectile dysfunction); − colchicine (used to treat gout) if you have kidney and/or liver problems (see the section on Other medicines and Norvir);
Croatian: − avanafil ili vardenafil (lijek za liječenje erektilne disfunkcije); − kolhicin (lijek koji se koristi za liječenje gihta) ako imate tegobe s bubrezima i/ili jetrom
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING NORVIR FILM-COATED TABLETS - Multipack containing 90 (3 bottles of 30) film-coated tablets with blue box
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU NORVIR FILMOM OBLOŽENE TABLETE - Višestruko pakiranje koje sadrži 90 (3 boce po
English: Initiate treatment with saquinavir 500 mg twice daily with ritonavir 100 mg twice daily for the first 7 days, then saquinavir 1000 mg twice daily with ritonavir 100 mg twice daily in ARTnaïve patients.
Croatian: Početak liječenja sa sakvinavirom 500 mg dva puta na dan s ritonavirom 100 mg dva puta na dan u prvih 7 dana, zatim sakvinavir 1000 mg dva puta na dan s ritonavirom 100 mg dva puta na dan kod bolesnika koji nisu prethodno primali antiretrovirusno liječenje.
English: Concomitant use of Norvir with lomitapide is contraindicated (see prescribing information for lomitapide) (see section 4.3).
Croatian: Istodobna primjena lijeka Norvir i lomitapida je kontraindicirana (vidjeti sažetak opisa svojstava lijeka za lomitapid) (vidjeti dio 4.3).
English: The concomitant use of tadalafil for the treatment of erectile dysfunction with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer should be with caution at reduced doses of no more than 10 mg tadalafil every 72 hours with increased monitoring for adverse reactions (see section 4.4).
Croatian: Tadalafil za liječenje erektilne disfunkcije istodobno s ritonavirom kao antiretrovirusnim lijekom ili kao farmakokinetičkim pojačivačem treba davati oprezno, u manjim dozama, ne većima od 10 mg tadalafila svaka 72 sata i uz pažljivije praćenje mogućih nuspojava (vidjeti dio 4.4).
English: Concomitant use of ritonavir dosed as an antiretroviral agent and voriconazole is contraindicated due to reduction in voriconazole concentrations (see section 4.3).
Croatian: Primjena ritonavira kao antiretrovirusnog lijeka istodobno s vorikonazolom je kontraindicirana zbog smanjenja koncentracija vorikonazola (vidjeti dio 4.3).
English: Induction of CYP1A2 and CYP2C9 lead to decreased levels of Rwarfarin while little pharmacokinetic effect is noted on S- warfarin when co-administered with ritonavir.
Croatian: Zbog indukcije CYP1A2 i CYP2C9 snižavaju se razine R-varfarina, dok je na
English: Co-administration of abemaciclib and Norvir should be avoided.
Croatian: Potrebno je izbjegavati istodobnu primjenu abemacikliba i lijeka Norvir.
English: Step 1.
Croatian: Korak 1.
English: Due to reductions in ethinyl estradiol concentrations, barrier or other non-hormonal methods of contraception should be considered with concomitant ritonavir use when dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Croatian: Zbog smanjenja koncentracija etinilestradiola valja razmotriti korištenje mehaničkih ili drugih nehormonskih metoda kontracepcije pri istodobnoj primjeni ritonavira kao antiretrovirusnog lijeka ili kao farmakokinetičkog pojačivača.
English: 600 q12h 2 h later
Croatian: 600 svakih 12h 2 h kasnije
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING NORVIR FILM-COATED TABLETS - CARTON WITH BLUE BOX
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU NORVIR FILMOM OBLOŽENE TABLETE - KUTIJA UKLJUČUJUĆI PLAVI OKVIR
English: Ritonavir steady-state pharmacokinetic parameters were evaluated in HIV infected children less than 2 years of age receiving doses ranging from 350 to 450 mg/m² twice daily.
Croatian: Pokazatelji farmakokinetike ritonavira u stanju dinamičke ravnoteže evaluirani su u bolesnika zaraženih HIV-om mlađih od 2 godine, koji su primali doze u rasponu od 350 do 450 mg/m2 dva puta na dan.
English: Each sachet of powder for oral suspension contains 100 mg of ritonavir.
Croatian: Jedna vrećica praška za oralnu suspenziju sadrži 100 mg ritonavira.
English: 200 q12h, 13 days
Croatian: 200 svakih 12h, 13 dana
English: Norvir 100 mg film-coated tablets
Croatian: Norvir 100 mg filmom obložene tablete
English: 500 q12h,
Croatian: 500 svakih 12h,
English: Administration with a high fat meal (917 kcal, 60% calories from fat) was associated with a mean decrease of 32 and 49% in ritonavir AUCinf and Cmax respectively, relative to fasting conditions.
Croatian: Primjena s obrokom s visokim udjelom masti (917 kcal, 60% kalorija iz masti) je bila povezana sa srednjim smanjenjem AUCinf vrijednosti od 32% i Cmax vrijednosti od 49% u odnosu na primjenu natašte.
English: 50 µg, single dose 500 q12h
Croatian: 50 µg, jednokratna doza 500 svakih
English: Co-administration of ritonavir and medicinal products primarily metabolised by CYP3A may result in increased plasma concentrations of the other medicinal product, which could increase or prolong its therapeutic and adverse effects.
Croatian: Pri istodobnoj primjeni ritonavira s lijekovima koji se prvenstveno metaboliziraju putem CYP3A mogu se povećati plazmatske koncentracije drugog lijeka i time povećati ili produžiti njegovi terapijski, ali i neželjeni učinci.
English: Ritonavir steady-state pharmacokinetic parameters were evaluated in HIV infected children above 2 years of age receiving doses ranging from 250 mg/m² twice daily to 400 mg/m² twice daily.
Croatian: Pokazatelji farmakokinetike ritonavira u stanju dinamičke ravnoteže evaluirani su u djece zaražene HIV-om starije od 2 godine, koja su primala doze u rasponu od 250 mg/m2 dva puta na dan do 400 mg/m2 dva puta na dan.
English: Events noted as having a frequency not known were identified via post-marketing surveillance
Croatian: Događaji nepoznate učestalosti su oni prijavljeni praćenjem nakon stavljanja lijeka u promet
English: Using the syringe Reading the scale a. Each millilitre (ml) is shown as a number with a big line.
Croatian: Svaki mililitar (ml) je prikazan kao broj pored duže linije.
English: b. Check for any lumps of powder.
Croatian: b. Provjerite je li ostalo grudica praška.
English: There is no parenteral formulation of ritonavir, therefore the extent of absorption and absolute bioavailability has not been determined.
Croatian: Apsorpcija Budući da nema ritonavira za parenteralnu primjenu, stupanj apsorpcije ni apsolutna bioraspoloživost nisu određeni.
English: - Feeling sick (nausea), vomiting or have stomach pain, because these may be signs of inflammation of the pancreas (pancreatitis).
Croatian: − Mučnina, povraćanje ili bol u želucu, jer to mogu biti znakovi upale gušterače (pankreatitis).
English: Step 12.
Croatian: Korak 12.
English: What you need to know before you or your child takes Norvir).
Croatian: Što morate znati prije nego što Vi ili Vaše dijete počnete uzimati Norvir).
English: For further dosage recommendations, refer to the product information of other Protease Inhibitors approved for co-administration with ritonavir.
Croatian: Za ostale preporuke o doziranju pročitati informacije o lijeku za druge inhibitore proteaza, odobrene za primjenu u kombinaciji s ritonavirom.
English: Pharmacokinetic data indicated that no dose adjustment is necessary for elderly patients (see section
Croatian: Farmakokinetički podaci pokazuju da ne treba prilagođavati dozu u starijih bolesnika (vidjeti dio 5.2).
English: This interaction may be due to modification of P-glycoprotein mediated digoxin efflux by ritonavir dosed as an antriretroviral agent or as a pharmacokinetic enhancer.
Croatian: Ta je interakcija možda posljedica promjene istjecanja digoksina posredovanog P-glikoproteinom pod utjecajem ritonavira doziranog kao antiretrovirusnog lijeka ili kao farmakokinetičkog pojačivača.
English: However, if the benefit outweighs the risk, coadministration of bedaquiline with ritonavir must be done with caution.
Croatian: Međutim, ukoliko korist nadmašuje rizik, prilikom istodobne primjene bedakilina s ritonavirom potreban je oprez.
English: Serum concentrations may be increased due to P-glycoprotein, BCRP and OATP1B inhibition by ritonavir.
Croatian: Serumske se koncentracije mogu povećati zbog inhibicijskog učinka ritonavira na P-glikoprotein, BCRP i OATP1B (polipeptid za prijenos organskih aniona (engl. organic anion transporting polypeptide)).
English: - Norvir is not a cure for HIV infection or AIDS.
Croatian: − Norvir nije lijek za izlječenje HIV-infekcije ni AIDS-a.
English: Step 10.
Croatian: Korak 10.
English: All measuring should be done in ml using the syringe.
Croatian: Svo mjerenje mora biti uz pomoć štrcaljke, u mililitrima.