FrancophonIA/ELRC3.0 huggingface dataset:
English: It is recommended that live viral or live bacterial vaccines (such as Bacillus of Calmette and Guérin (BCG)) should not be given concurrently with STELARA.
Slovenian: Priporočljivo je, da živih virusnih ali živih bakterijskih cepiv (na primer cepiva z Bacillusom Calmette-Guérin - BCG) ne dajete v času zdravljenja z zdravilom STELARA.
English: Similar disease severity was also seen in Psoriasis Study 3.
Slovenian: Značilnosti bolezni so bile podobne tudi v 3. študiji psoriaze.
English: In Psoriasis Study 1 maintenance of PASI 75 was significantly superior with continuous treatment compared with treatment withdrawal (p < 0.001).
Slovenian: V 1. študiji psoriaze je bilo ohranjanje PASI 75 bistveno boljše pri neprekinjenem zdravljenju kot pri prenehanju zdravljenja (p < 0,001).
English: • Put the vial on a flat surface.
Slovenian: • Vialo položite na ravno površino.
English: Check the number of vials and prepare the materials:
Slovenian: Preverite število vial in si vse pripravite:
English: Psoriasis Study 2 (PHOENIX 2) evaluated 1,230 patients.
Slovenian: V 2. študiji psoriaze (PHOENIX 2) so ovrednotili 1.230 bolnikov.
English: Efficacy results presented for UNIFI-I and UNIFI-M were based on central review of endoscopies.
Slovenian: Prikazani rezultati za oceno učinkovitosti iz študij UNIFI-I in UNIFI-M temeljijo na ocenah centralnega pregleda endoskopij.
English: Take the vial(s) out of the refrigerator.
Slovenian: Vialo (viali) vzemite iz hladilnika.
English: Psoriasis Study 1 (PHOENIX 1) evaluated 766 patients.
Slovenian: V 1. študiji psoriaze (PHOENIX 1) so ovrednotili podatke za 766 bolnikov.
English: • If you are allergic to ustekinumab or any of the other ingredients of this medicine (listed in section 6).
Slovenian: • če ste alergični na ustekinumab ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
English: All patients, in particular those greater than 60 years of age, patients with a medical history of prolonged immunosuppressant therapy or those with a history of PUVA treatment, should be monitored for the appearance of non-melanoma skin cancer (see section 4.8).
Slovenian: Vse bolnike, še posebno pa bolnike, starejše od 60 let, bolnike, ki so dolgo časa prejemali imunosupresive ali tiste, ki so prejemali zdravljenje s PUVA, je treba spremljati zaradi možnosti pojava nemelanomskega kožnega raka (glejte poglavje 4.8).
English: It is unknown whether ustekinumab is excreted in human breast milk.
Slovenian: Ni znano, ali se ustekinumab izloča v materino mleko pri človeku.
English: Treatment of latent tuberculosis infection should be initiated prior to administering STELARA.
Slovenian: Zdravljenje latentne tuberkulozne okužbe je treba začeti še pred uporabo zdravila STELARA.
English: • Good places for the injection are the upper thigh or around the belly (abdomen) at least 5 cm away from the navel (belly button)
Slovenian: • Primerna mesta za injiciranje zdravila so zgornji del stegna ali trebuh (abdomen), in sicer najmanj 5 cm stran od popka.
English: Push it slowly and evenly, keeping the skin gently pinched
Slovenian: Bat potiskajte počasi in enakomerno ter pri tem nežno stiskajte kožo v gubo.
English: In case of overdose, it is recommended that the patient be monitored for any signs or symptoms of adverse reactions and appropriate symptomatic treatment be instituted immediately.
Slovenian: V primeru prevelikega odmerjanja je priporočljivo, da bolnika spremljate, da bi lahko ugotovili morebitne znake in simptome neželenih učinkov ter jim takoj uvedli ustrezno simptomatsko zdravljenje.
English: Week 12 2 doses (week 0 and week 4)
Slovenian: 12. teden 2 odmerka (v tednu 0 in 4)
English: The solution is clear to slightly opalescent, colourless to light yellow and may contain a few small translucent or white particles of protein.
Slovenian: Raztopina je bistra do rahlo opalescentna in brezbarvna do svetlo rumena ter lahko vsebuje nekaj majhnih prosojnih ali belih beljakovinskih delcev.
English: Your doctor may decide that you should not use Stelara until the infection goes away.
Slovenian: Zdravnik se lahko odloči, da zdravila Stelara ne smete jemati, dokler traja okužba.
English: If you forget to use Stelara
Slovenian: Če ste pozabili uporabiti zdravilo Stelara
English: • Do not mix Stelara with other liquids for injection
Slovenian: • Zdravila Stelara ne smete mešati z drugimi tekočinami za injiciranje.
English: Your body weight
Slovenian: Vaša telesna masa
English: • the solution in the pre-filled syringe is not frozen.
Slovenian: • da raztopina v napolnjeni injekcijski brizgi ni zmrznjena.
English: Impact of weight on pharmacokinetics
Slovenian: Vpliv telesne mase na farmakokinetiko
English: These may be signs of infections such as chest infections, or skin infections or shingles that could have serious complications.
Slovenian: To so lahko znaki okužbe spodnjih dihal, okužbe kože ali pasavec, zaradi katerih lahko pride do resnih zapletov.
English: • If possible, do not use areas of skin that show signs of psoriasis
Slovenian: • Če je mogoče, zdravila ne injicirajte na mesta, ki kažejo znake psoriaze.
English: • Slowly take your thumb off the plunger head to allow the empty syringe to move up until the entire needle is covered by the needle guard, as shown by Figure 7:
Slovenian: • Počasi umaknite palec z glave bata, da se prazna brizga pomakne navzgor, dokler ni cela igla prekrita s ščitnikom, kot je prikazano na Sliki 7:
English: CDLQI: The CDLQI is a dermatology instrument to assess the effect of a skin problem on the health-related quality of life in the paediatric population.
Slovenian: CDLQI: CDLQI je dermatološki pripomoček za oceno učinka težav s kožo na z zdravjem povezane kakovosti življenja pri pediatrični populaciji.
English: Antibodies to ustekinumab may develop during ustekinumab treatment and most are neutralising.
Slovenian: Med zdravljenjem z ustekinumabom se lahko razvijejo protitelesa proti ustekinumabu, ki so večinoma nevtralizirajoča.
English: In general, the adverse events reported in these two studies with safety data up to 1 year were similar to those seen in previous studies in adults with plaque psoriasis.
Slovenian: Na splošno so bili poročani neželeni učinki v teh dveh študijah (z vključenimi podatki o varnosti do 1 leta) podobni neželenim učinkom, poročanim v študijah psoriaze s plaki pri odraslih.
English: How much Stelara is given Your doctor will decide how much Stelara you need to use and for how long.
Slovenian: Koliko zdravila Stelara uporabimo Zdravnik bo presodil, koliko zdravila Stelara potrebujete in kako dolgo ga boste jemali.
English: The final volume in the infusion bag should be 250 mL.
Slovenian: Končni volumen v infuzijski vrečki mora biti 250 ml. Nežno premešajte.
English: If you are the parent or caregiver who will give Stelara to a child, please read this information carefully.
Slovenian: Če ste starš ali skrbnik, ki bo zdravilo Stelara dajal otroku, vas prosimo, da navodilo skrbno preberete.
English: Similarly, significant improvements were seen in Psoriasis Study 2 at week 4 and 12, which were sustained through week 24.
Slovenian: Podobna statistično značilna izboljšanja so dokazali v 2. študiji psoriaze v 4. in 12. tednu, trajala pa so tudi v 24. tednu.
English: Animal studies have shown excretion of ustekinumab at low levels in breast milk.
Slovenian: Študije na živalih so pokazale izločanje ustekinumaba v materino mleko v majhnih koncentracijah.
English: The primary endpoint was the percentage of patients who achieved American College of Rheumatology (ACR) 20 response at week 24.
Slovenian: Primarni končni rezultat je bil delež bolnikov, ki so po 24. tednih dosegli odziv 20 po merilih Ameriškega revmatološkega združenja (ACR - American College of Rheumatology criteria).
English: Patients receiving STELARA should be monitored closely for signs and symptoms of active tuberculosis during and after treatment.
Slovenian: Bolnike, ki prejemajo zdravilo STELARA, je treba natančno spremljati, da bi pri njih lahko ugotovili znake in simptome aktivne tuberkuloze, tako med zdravljenjem kot po njem.
English: Choose an injection site (see Figure 2)
Slovenian: Izberite mesto injiciranja (glejte Sliko 2)
English: As a precautionary measure, it is preferable to avoid the use of STELARA in pregnancy.
Slovenian: Kot varnostni ukrep se je med nosečnostjo bolje izogibati uporabi zdravila STELARA.
English: Children and adolescents aged 6 years or older
Slovenian: Otroci in mladostniki, stari 6 let in več
English: Let the vial stand for about half an hour.
Slovenian: Vialo pustite na sobni temperaturi približno pol ure.
English: Patients with each subtype of PsA were enrolled, including polyarticular arthritis with no evidence of rheumatoid nodules (39%), spondylitis with peripheral arthritis (28%), asymmetric peripheral arthritis (21%), distal interphalangeal involvement (12%) and arthritis mutilans (0.5%).
Slovenian: Vključeni so bili bolniki z vsemi podtipi PsA, vključno poliartikularnim artritisom brez revmatoidnih vozličev (39%), spondilitisom s perifernim artritisom (28%), asimetričnim perifernim artritisom (21%), distalnimi interfalangealnimi zapleti (12%) in artritisom mutilansom (0,5%).
English: Ask your doctor if you are not sure.
Slovenian: Če niste prepričani, vprašajte svojega zdravnika.
English: Serious side effects Some patients may have serious side effects that may need urgent treatment.
Slovenian: Pri nekaterih bolnikih se lahko pojavijo tudi resni neželeni učinki, zaradi katerih je potrebno nujno zdravljenje.
English: What you need to know before you use Stelara
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo Stelara
English: Serious hypersensitivity reactions have been reported in the postmarketing setting, in some cases several days after treatment.
Slovenian: Pri uporabi v obdobju trženja zdravila so poročali o resnih preobčutljivostnih reakcijah, ki so se (v nekaterih primerih) pojavile več dni po aplikaciji zdravila.
English: Patients enrolled PGA
Slovenian: Vključeni bolniki PGA
English: At week 12, placebo treated patients crossed over to receive ustekinumab.
Slovenian: V 12. tednu so bolniki, ki so prejemali placebo prešli na zdravljenje z ustekinumabom.
English: Plaque psoriasis is a skin condition that causes inflammation affecting the skin and nails.
Slovenian: Psoriaza s plaki je kožna bolezen, ki povzroči vnetje kože in nohtov.
English: 100 people)
Slovenian: 100 bolnikov).
English: The primary endpoint for the induction study was the proportion of subjects in clinical remission at week 8.
Slovenian: Primarni cilj opazovanja v študiji indukcijskega zdravljenja je bil delež preiskovancev v klinični remisiji po 8 tednih.
English: Patients randomised PGA
Slovenian: Randomizirani bolniki PGA
English: > 55 kg to ≤ 85 kg
Slovenian: > 55 kg do ≤ 85 kg
English: It is not known whether STELARA may affect allergy immunotherapy.
Slovenian: Ni znano ali zdravilo STELARA lahko vpliva na imunoterapijo proti alergiji.
English: In patients who have responded to treatment with STELARA, corticosteroids may be reduced or discontinued in accordance with standard of care.
Slovenian: Pri bolnikih, ki so se odzvali na zdravljenje z zdravilom STELARA, bo morda treba zmanjšati odmerek kortikosteroida ali ga ukiniti, skladno z ustaljeno klinično prakso.
English: • Wash your hands very well with soap and warm water
Slovenian: • Z milom in toplo vodo si temeljito umijte roke.
English: Endoscopic appearance of the mucosa was evaluated in 252 patients with eligible baseline endoscopic disease activity in a substudy.
Slovenian: V podštudiji so ocenjevali endoskopski izgled sluznice pri 252 bolnikih z razpoložljivo endoskopsko oceno aktivnosti bolezni ob izhodišču.
English: Use only an infusion set with an in-line, sterile, non-pyrogenic, low protein-binding filter (pore size 0.2 micrometer).
Slovenian: Uporabite lahko le infuzijske komplete, opremljene z linijskim sterilnim, apirogenim filtrom, ki minimalno veže beljakovine (velikost por 0,2 mikrometra).
English: Of those patients, 9% of patients who were initially randomized to the recommended induction dose achieved clinical remission and 58% achieved clinical response at Week 16.
Slovenian: Izmed teh bolnikov je 9% bolnikov, ki so bili sprva randomizirani na priporočeni indukcijski odmerek, v 16. tednu doseglo klinično remisijo, 58% pa klinični odziv.
English: Week 28 3 doses (week 0, week 4 and week 16) PBO 45 mg 90 mg 45 mg 90 mg
Slovenian: 28. teden 3 odmerki (v tednih 0, 4 in 16) PBO 45 mg 90 mg 45 mg 90 mg
English: Concomitant doses of oral corticosteroids, immunomodulators, aminosalicylates and antibiotics were permitted and 75% of patients continued to receive at least one of these medications.
Slovenian: Dovoljeno je bilo sočasno odmerjanje peroralnih kortikosteroidov, imunomodulatorjev, aminosalicilatov in antibiotikov in 75% bolnikov je nadaljevalo s sočasnim prejemanjem vsaj enega od teh zdravil.
English: • Remove the needle from the vial
Slovenian: • Izvlecite iglo iz viale.
English: • If the liquid is discoloured, cloudy or you can see other foreign particles floating in it (see section 6 ‘What Stelara looks like and contents of the pack').
Slovenian: • če je tekočina obarvana ali motna ali če v njej plavajo drugi tuji delci (glejte poglavje 6, ‘Izgled zdravila Stelara in vsebina pakiranja');
English: In psoriasis studies, the safety and efficacy of STELARA in combination with immunosuppressants, including biologics, or phototherapy have not been evaluated.
Slovenian: V študijah psoriaze varnosti in učinkovitosti zdravila STELARA v kombinaciji z imunosupresivi, vključno z biološkimi zdravili ali fototerapijo, še niso ovrednotili.
English: The induction studies included 1409 (UNITI-1, n = 769; UNITI-2 n = 640) patients.
Slovenian: V študiji indukcije UNITI-1 in UNITI-2 so vključili 1.409 bolnikov (UNITI-1 n = 769; UNITI-2 n = 640).
English: Patients who have not shown adequate response at 8 weeks after the first subcutaneous dose, may receive a second subcutaneous dose at this time (see section 5.1).
Slovenian: Bolniki, pri katerih ni zadostnega odziva 8 tednov po prvem subkutanem odmerku, lahko takrat prejmejo drugi subkutani odmerek (glejte poglavje 5.1).
English: Patients should be instructed to seek medical advice if signs or symptoms suggestive of an infection occur.
Slovenian: Bolnikom naročite, naj se posvetujejo z zdravnikom, če se pojavijo znaki ali simptomi, ki kažejo na okužbo.
English: Corticosteroid-free clinical remission is defined as patients in clinical remission and not receiving corticosteroids at Week 44.
Slovenian: Klinična remisija brez kortikosteroidov je definirana kot bolniki, ki so v 44. tednu v klinični remisiji in ne prejemajo kortikosteroidov.
English: The syringe, needle and vial must never be re-used.
Slovenian: Injekcijske brizge, igle in viale ne smete ponovno uporabiti.
English: Patients with body weight > 100 kg
Slovenian: Bolniki s telesno maso > 100 kg
English: STELARA has not been evaluated in patients who have undergone allergy immunotherapy.
Slovenian: Zdravila STELARA niso preskušali pri bolnikih, ki so prejeli imunoterapijo proti alergiji.
English: • Gently pinch the cleaned skin between your thumb and index finger.
Slovenian: • Nežno stisnite očiščeno kožo s palcem in kazalcem.
English: Following the recommended intravenous induction dose, median peak serum ustekinumab concentration, observed 1 hour after the infusion, was 126.1 μg/mL in patients with Crohn's disease and 127.0 µg/mL in patients with ulcerative colitis.
Slovenian: Po priporočenem začetnem intravenskem indukcijskem odmerku je bila 1 uro po infuziji največja mediana serumska koncentracija ustekinumaba 126,1 μg/ml pri bolnikih s Crohnovo boleznijo in 127,0 µg/ml pri bolnikih z ulceroznim kolitisom.
English: Structural damage in both hands and feet was expressed as change in total van der Heijde-Sharp score (vdH-S score), modified for PsA by addition of hand distal interphalangeal joints, compared to baseline.
Slovenian: Strukturne spremembe dlani in stopal so bile izražene kot spremembe celokupne ocene po metodi Heijde-Sharp (rezultat vdH-S), modificirane za PsA z dodatkom distalnih interfalangealnih sklepov dlani v primerjavi z začetno vrednostjo.
English: Patients receiving ustekinumab experienced significantly more improvements in work productivity as assessed by greater reductions in overall work impairment and in activity impairment as assessed by the WPAI-GH questionnaire than patients receiving placebo.
Slovenian: Pri bolnikih, ki so prejemali ustekinumab, je prišlo do občutnega izboljšanja delovne storilnosti z ozirom na večje zmanjšanje odsotnosti z dela in zmanjšane aktivnosti, ocenjenih z vprašalnikom WPAI-GH, kot pri bolnikih, ki so prejemali placebo.
English: There is no apparent correlation between the presence of anti-ustekinumab antibodies and the occurrence of injection site reactions.
Slovenian: Prav tako niso opazili očitne povezave med nastankom protiteles in pojavom reakcije na mestu injiciranja.
English: • Moderate to severe Crohn's disease - in adults
Slovenian: • zmerno do močno aktivne Crohnove bolezni - pri odraslih
English: Responses observed in the ustekinumab treated groups were similar in patients receiving and not receiving concomitant MTX, and were maintained through weeks 52 and 100.
Slovenian: Odzivi v skupininah bolnikov, ki so prejemale ustekinumab so bili podobni odzivu pri bolnikih, ki so/niso prejemali MTX sočasno in so se ohranili do 52. in do 100. tedna.
English: Carcinogenicity studies were not performed with ustekinumab due to the lack of appropriate models for an antibody with no cross-reactivity to rodent IL-12/23 p40.
Slovenian: Študije kancerogenosti ustekinumaba niso bile opravljene, ker ni ustreznih modelov protiteles brez navzkrižne reaktivnosti na glodalske IL-12/23 p40.
English: If a patient develops a serious infection, the patient should be closely monitored and STELARA should not be administered until the infection resolves.
Slovenian: Če bolnik dobi resno okužbo, ga morate pozorno spremljati in mu zdravila STELARA ne smete več dajati, dokler okužba ne izzveni.
English: 51% of patients had failed or were intolerant to a biologic.
Slovenian: Pri 51% bolnikov je bilo neuspešno predhodno zdravljenje z biološkim zdravilom ali pa ga niso prenašali.
English: • If you are having any other treatment for psoriasis and/or psoriatic arthritis - such as another immunosuppressant or phototherapy (when your body is treated with a type of ultraviolet (UV) light).
Slovenian: • če jemljete katero koli drugo zdravilo za zdravljenje psoriaze in/ali psoriatičnega artritisa, kot so drug imunosupresiv ali fototerapijo (obsevanje telesa s posebno ultravijolično (UV) svetlobo).
English: PedsQL: The PedsQL Total Scale Score is a general health-related quality of life measure developed for use in children and adolescent populations.
Slovenian: PedsQL: PedsQL je splošno merilo za z zdravjem povezano kakovost življenja pri otrocih in mladostnikih.
English: Concomitant doses of oral corticosteroids, immunomodulators, and aminosalicylates were permitted and 90% of patients continued to receive at least one of these medications.
Slovenian: Dovoljeno je bilo sočasno odmerjanje peroralnih kortikosteroidov, imunomodulatorjev in aminosalicilatov in 90% bolnikov je nadaljevalo s sočasnim prejemanjem vsaj enega od teh zdravil.
English: If you have ulcerative colitis you will first be given other medicines.
Slovenian: Če imate ulcerozni kolitis, se boste najprej zdravili z drugimi zdravili.
English: In the placebo-controlled period of these clinical studies, the rate of infection was 1.36 per patient-year of follow-up in ustekinumab-treated patients, and 1.34 in placebo-treated patients.
Slovenian: V s placebom nadzorovanem obdobju teh kliničnih študij je bila pogostnost okužb 1,36 na bolnikov-let spremljanja pri bolnikih, zdravljenih z ustekinumabom, oziroma 1,34 pri bolnikih, zdravljenih s placebom.
English: In these patients, clinical remission was achieved in 41.4% of patients 16 weeks after dose adjustment.
Slovenian: Pri 41,4% teh bolnikov je bila klinična remisija dosežena 16 tednov po prilagoditvi odmerjanja.
English: All patients were followed for up to 76 weeks following first administration of study treatment.
Slovenian: Vse bolnike so spremljali do 76 tednov po prvem prejemu preučevanega zdravila.
English: • Bleeding, bruising, hardness, swelling and itching where the injection is given
Slovenian: • krvavitve, potpludbe, zatrdlina, otekanje in srbenje na mestu injiciranja zdravila
English: • Tooth infections
Slovenian: • okužba zob
English: Anti-tuberculosis therapy should also be considered prior to initiation of STELARA in patients with a history of latent or active tuberculosis in whom an adequate course of treatment cannot be confirmed.
Slovenian: Pred začetkom zdravljenja z zdravilom STELARA je treba zdravljenje tuberkuloze uvesti tudi pri bolnikih z latentno ali aktivno tuberkulozo v anamnezi, pri katerih ni mogoče potrditi, da so opravili ustrezen cikel zdravljenja.
English: (see section 4.4).
Slovenian: (glejte Sliko 4).
English: Long term treatment with STELARA does not suppress the humoral immune response to pneumococcal polysaccharide or tetanus vaccines (see section 5.1).
Slovenian: Dolgotrajno zdravljenje z zdravilom STELARA ne zavira humoralnega imunskega odziva na pnevmokokne polisaharide ali cepivo proti tetanusu (glejte poglavje 5.1).
English: Efficacy (defined as PGA 0 or 1) was observed as early as the first post-baseline visit at week 4 and the proportion of subjects who achieved a PGA score of 0 or 1 increased through week 16 and then remained relatively stable through week 52.
Slovenian: Učinkovitost (definirano z oceno PGA 0 ali 1) so opazili že pri prvem obisku po začetku zdravljenja (4. teden) in delež bolnikov, ki so dosegli oceno PGA 0 ali 1, se je povečeval do 16. tedna in nato ostal relativno stabilen do 52. tedna.
English: 3 years.
Slovenian: 3 leta Ne zamrzujte.
English: Signs include: o difficulty breathing or swallowing o low blood pressure, which can cause dizziness or light-headedness o swelling of the face, lips, mouth or throat.
Slovenian: Znaki so: o težave pri dihanju ali požiranju, o nizek krvni tlak, ki lahko povzroči vrtoglavico ali omotico, o otekanje obraza, ustnic, ust ali žrela.
English: Check the number of pre-filled syringes and prepare the materials:
Slovenian: Preverite število napolnjenih injekcijskih brizg in si vse pripravite:
English: (kg) may start on a dose of 90 mg instead of 45 mg.
Slovenian: 100 kilogramov (kg), lahko prejmejo 90 mg namesto 45 mg.
English: In patients with psoriasis, exfoliative dermatitis has been reported following ustekinumab treatment (see section 4.8).
Slovenian: Pri bolnikih s psoriazo so po zdravljenju z ustekinumabom poročali o eksfoliativnem dermatitisu (glejte poglavje 4.8).
English: • Plaque psoriasis - in adults and children aged 6 years and older
Slovenian: • psoriaza s plaki pri odraslih in otrocih, starih 6 let in več
English: Live vaccines should not be given concurrently with STELARA (see section 4.4).
Slovenian: Živih cepiv se ne sme dajati sočasno z zdravilom STELARA (glejte poglavje 4.4).
English: • Clean the stopper with an antiseptic swab
Slovenian: • Očistite zamašek z antiseptičnim zložencem.
English: No pharmacokinetic data are available in patients with impaired renal or hepatic function.
Slovenian: Farmakokinetični podatki o bolnikih z zmanjšanim delovanjem ledvic ali jeter niso na voljo.
English: Patients with a CDLQI > 1 at baseline
Slovenian: Bolniki s CDLQI > 1 ob izhodišču
English: The infusion solution is to be composed of the number of vials of STELARA 130 mg as specified in Table 1 (see section 6.6 for preparation).
Slovenian: Infuzijska raztopina zdravila STELARA 130 mg se pripravi iz števila vial, kot je navedeno v Preglednici 1 (za pripravo glejte poglavje 6.6).
English: Population pharmacokinetic analysis showed that there was a trend towards a higher clearance of ustekinumab in patients who tested positive for antibodies to ustekinumab.
Slovenian: Analiza populacijske farmakokinetike je pokazala nagnjenost k večjemu očistku ustekinumaba pri bolnikih, ki so imeli pozitiven izvid preiskave na protitelesa proti ustekinumabu.