FrancophonIA/ELRC3.0 huggingface dataset:
English: If your liver is not working properly, the usual dose should not exceed 40 mg/12.5 mg once a day.
Slovenian: Če vam jetra ne delujejo pravilno, običajni odmerek ne sme prekoračiti 40 mg/12,5 mg 1-krat dnevno.
English: Thrombocytopenia (sometimes with purpura)
Slovenian: trombocitopenija (včasih s purpuro)
English: What Actelsar HCT is and what it is used for
Slovenian: Kaj je zdravilo Actelsar HCT in za kaj ga uporabljamo
English: There are no adequate data from the use of Actelsar HCT in pregnant women.
Slovenian: Ni zadostnih podatkov o uporabi zdravila Actelsar HCT pri nosečnicah.
English: Furthermore, low blood pressure may be aggravated by alcohol, barbiturates, narcotics or antidepressants.
Slovenian: Poleg tega lahko nizek krvni tlak poslabšajo alkohol, barbiturati, narkotiki ali antidepresivi.
English: The overall incidence of adverse reactions reported with telmisartan (41.4%) was usually comparable to placebo (43.9%) in placebo controlled trials.
Slovenian: Skupna pogostnost neželenih učinkov, o kateri so poročali za telmisartan (41,4 %), je bila večinoma primerljiva s podatki za placebo (43,9 %) v kliničnih preskušanjih nadzorovanih s placebom.
English: It is important that you take Actelsar HCT every day until your doctor tells you otherwise.
Slovenian: Zdravilo Actelsar HCT morate jemati vsak dan, dokler vam ga bo zdravnik predpisoval.
English: Plasma concentrations of telmisartan are generally 2-3 times higher in females than in males.
Slovenian: Koncentracije telmisartana v plazmi so pri ženskah večinoma 2- do 3-krat večje kot pri moških.
English: - Hypersensitivity to other sulphonamide-derived substances (since hydrochlorothiazide is a sulphonamide-derived medicinal product).
Slovenian: - Preobčutljivost na druge sulfonamidne derivate (ker je hidroklorotiazid sulfonamidni derivat).
English: - Muscle relaxing medicines, such as tubocurarine.
Slovenian: - zdravila, ki sproščajo mišice, kot je tubokurarin;
English: The European Medicines Agency has waived the obligation to submit the results of studies with telmisartan hydrochlorothiazide in all subsets of the paediatric population in hypertension (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Actelsar HCT za vse podskupine pediatrične populacije s hipertenzijo (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: - Severe renal impairment (creatinine clearance <30 ml/min).
Slovenian: - Huda ledvična okvara (kreatininski očistek < 30 ml/min).
English: After a single dose of 14C-labelled telmisartan the glucuronide represents approximately 11% of the measured radioactivity in plasma.
Slovenian: Po enkratnem odmerku s C14 označenega telmisartana odpade na glukuronid približno 11 % radioaktivnosti, izmerjene v plazmi.
English: Pharmacotherapeutic group: Agents acting on the renin-angiotensin system; angiotensin II antagonists and diuretics, ATC code: C09DA07
Slovenian: Farmakoterapevtska skupina: zdravila z delovanjem na renin-angiotenzinski sistem; antagonisti angiotenzina II in diuretiki, oznaka ATC: C09DA07
English: Adverse reactions reported in all clinical trials and occurring more frequently (p≤0.05) with telmisartan plus hydrochlorothiazide than with placebo are shown below according to system organ class.
Slovenian: Neželeni učinki, o katerih so poročali v vseh kliničnih preskušanjih in so se pojavljali pogosteje (p ≤ 0,05) pri telmisartanu in hidroklorotiazidu kot pri placebu, so našteti po organskih sistemih.
English: Such conditions should be corrected before the administration of Actelsar HCT.
Slovenian: Tovrstna stanja je treba uravnati pred zdravljenjem z zdravilom Actelsar HCT.
English: If a re-administration of the diuretic is deemed necessary, it is recommended to protect exposed areas to the sun or to artificial UVA.
Slovenian: Če je treba diuretik ponovno uvesti, je priporočljivo izpostavljene dele telesa zaščititi pred soncem ali umetnimi ultravijoličnimi žarki.
English: Elimination Telmisartan: Following either intravenous or oral administration of 14C-labelled telmisartan most of the administered dose (>97%) was eliminated in faeces via biliary excretion.
Slovenian: Telmisartan: Po intravenskem ali peroralnem dajanju s 14C označenega telmisartana se je večina odmerka (> 97 %) izločila z blatom po biliarni poti.
English: The use of Actelsar HCT in children and adolescents up to the age of 18 years is not recommended.
Slovenian: Otroci in mladostniki Uporabe zdravila Actelsar HCT pri otrocih in mladostnikih do 18. leta ne priporočamo.
English: “Lot”, which is printed on the carton, refers to the batch number.
Slovenian: Oznaka »Lot« na škatli označuje številko serije.
English: Increase in dose of probenecid or sulfinpyrazone may be necessary.
Slovenian: Včasih je treba povečati odmerek probenecida ali sulfinpirazona.
English: Telmisartan may increase the hypotensive effect of other antihypertensive agents.
Slovenian: Drugi antihipertenzivi Telmisartan lahko poveča hipotenzivni učinek drugih antihipertenzivov.
English: Respiratory distress (including pneumonitis and pulmonary oedema)
Slovenian: dihalna stiska (vključno s pnevmonitisom in pljučnim edemom)
English: Some people feel dizzy or tired when taking Actelsar HCT.
Slovenian: Nekateri ljudje so med zdravljenjem z zdravilom Actelsar HCT omotični ali utrujeni.
English: Pharmacokinetic studies in patients with hepatic impairment showed an increase in absolute bioavailability up to nearly 100%.
Slovenian: Farmakokinetične raziskave so pri bolnikih z jetrno okvaro odkrile skoraj 100-odstotno povečanje absolutne biološke uporabnosti.
English: The terminal elimination half-life of hydrochlorothiazide is 10-15 hours.
Slovenian: Končna razpolovna doba izločanja je 10 do 15 ur.
English: You should also tell your doctor if you experience an increased sensitivity of the skin to the sun with symptoms of sunburn (such as redness, itching, swelling, blistering) occurring more quickly than normal.
Slovenian: Zdravnika prav tako obvestite, če se poveča občutljivost kože na sončne žarke in se znaki sončnih opeklin (rdečica, srbenje, oteklina, mehurji) pojavijo prej kot običajno.
English: If you accidentally take too many tablets you may experience symptoms such as low blood pressure and rapid heartbeat.
Slovenian: Če ste vzeli večji odmerek zdravila Actelsar HCT, kot bi smeli Če pomotoma vzamete preveč tablet, se lahko pojavijo simptomi, kot so nizek krvni tlak in pospešen srčni utrip.
English: Actelsar HCT is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Slovenian: Zdravila Actelsar HCT med nosečnostjo ne priporočajo; ne smete pa ga jemati, ko boste noseči več kot 3 mesece, ker lahko po tretjem mesecu nosečnosti resno škoduje vašemu otroku.
English: The effect of Actelsar HCT may be reduced when you take NSAIDs (non steroidal anti-inflammatory medicines, e.g. acetylsalicyl acid or ibuprofen).
Slovenian: Učinek zdravila Actelsar HCT se lahko zmanjša, če jemljete NSAR (nesteroidne antirevmatike, npr. acetilsalicilno kislino ali ibuprofen).
English: Food slightly reduces the bioavailability of telmisartan with a reduction in the area under the plasma concentration time curve (AUC) of about 6% with the 40 mg tablet and about 19% after a 160 mg dose.
Slovenian: Pri tem se območje pod krivuljo plazemske koncentracije v odvisnosti od časa (AUC) zmanjša za približno 6 % pri tabletah po 40 mg in za približno 19 % pri odmerkih po 160 mg.
English: You must tell your doctor if you think you are (or might become) pregnant.
Slovenian: Zdravniku morate povedati, če mislite, da ste (ali bi lahko bili) noseči.
English: An increase in cholesterol and triglyceride levels has been associated with thiazide diuretic therapy; however, at the 12.5 mg dose contained in Actelsar HCT, minimal or no effects were reported.
Slovenian: Z zdravljenjem s tiazidnimi diuretiki povezujejo povečanje ravni holesterola in trigliceridov, vendar za odmerek po 12,5 mg, ki ga vsebuje zdravilo Actelsar HCT, poročajo le o minimalnih ali nikakršnih tovrstnih učinkih.
English: In case of surgery or anaesthetics, you should tell your doctor that you are taking Actelsar HCT.
Slovenian: Če boste operirani ali boste dobili anestetike, morate zdravniku povedati, da jemljete zdravilo Actelsar HCT.
English: You should consult with your doctor if you need to adjust the dose of your other medicine while taking Actelsar HCT.
Slovenian: Z zdravnikom se morate posvetovati, ali je treba med jemanjem zdravila Actelsar HCT prilagoditi odmerek vašega drugega zdravila.
English: - Hyponatraemia and hypochloraemic alkalosis There is no evidence that Actelsar HCT would reduce or prevent diuretic-induced hyponatraemia.
Slovenian: - Hiponatriemija in hipokloremična alkaloza Ni podatkov, ki bi kazali, da zdravilo Actelsar HCT zmanjša ali prepreči hiponatriemijo, ki jo povzročajo diuretiki.
English: - Cholestyramine and colestipol, medicines for lowering blood fat levels.
Slovenian: - holestiramin in holestipol, zdravili za znižanje ravni maščob v krvi;
English: Angiotensin-II is a substance produced in your body which causes your blood vessels to narrow thus increasing your blood pressure.
Slovenian: Angiotenzin II je snov, ki nastaja v telesu in povzroča, da se krvne žile zožijo, kar zviša krvni tlak.
English: 3 For further description, please see sub-section “Description of selected adverse reactions”.
Slovenian: 3 Za podrobnejši opis glejte podpoglavje “Opis izbranih neželenih učinkov”.
English: Possible side effects of Actelsar HCT:
Slovenian: Možni neželeni učinki zdravila Actelsar HCT so:
English: Actelsar HCT is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section).
Slovenian: Uporaba zdravila Actelsar HCT ni priporočljiva v zgodnjem obdobju nosečnosti in ga ne smete jemati, če ste noseči več kot 3 mesece, ker lahko v tem obdobju resno škoduje vašemu otroku (glejte poglavje o nosečnosti).
English: Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy.
Slovenian: Med dejavniki tveganja za pojav akutnega glavkoma zaprtega zakotja so lahko alergije na sulfonamide ali penicilin v anamnezi.
English: If any of the above applies to you, tell your doctor or pharmacist before taking Actelsar HCT.
Slovenian: Če imate katero od naštetih stanj, povejte zdravniku ali farmacevtu preden boste vzeli zdravilo Actelsar HCT.
English: In addition, Actelsar HCT should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.
Slovenian: Zdravilo Actelsar HCT moramo previdno dajati tudi bolnikom z motnjami jetrnega delovanja ali napredujočo jetrno boleznijo, ker lahko že manjše spremembe ravnovesja tekočin in elektrolitov povzročijo jetrno komo.
English: Actelsar HCT is a combination of two active substances, telmisartan and hydrochlorothiazide in one tablet.
Slovenian: Zdravilo Actelsar HCT je kombinacija dveh zdravilnih učinkovin, telmisartana in hidroklorotiazida v eni tableti.
English: Take it as soon as you remember, then carry on as before.
Slovenian: Vzemite ga takoj, ko se spomnite, in z jemanjem nadaljujte kot običajno.
English: Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of telmisartan hydrochlorothiazide initiation.
Slovenian: Simptoma sta akutno poslabšanje ostrine vida ali očesna bolečina, ki se značilno pojavita v nekaj urah do nekaj tednih po začetku jemanja telmisartana/hidroklorotiazida.
English: Do not store above 30ºC
Slovenian: Shranjujte pri temperaturi do 30°C.
English: Al/Al blister, Al/PVC/PVDC blister and HDPE tablet container with LDPE cap and HDPE desiccant with silica filling.
Slovenian: Al/Al pretisni omot, Al/PVC/PVDC pretisni omot in HDPE vsebnik za tablete z LDPE pokrovčkom in HDPE sušilcem z silicijevim polnilom.
English: pentamidine, sparfloxacine, terfenadine, vincamine IV)
Slovenian: pentamidin, sparfloksacin, terfenadin, vinkamin i.v.)
English: Adverse reactions have been ranked under headings of frequency using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to
Slovenian: Neželeni učinki so razvrščeni po pogostnosti, za katero veljajo naslednji kriteriji: zelo pogosti (≥ 1/10); pogosti (≥ 1/100 do < 1/10); občasni (≥ 1/1.000 do < 1/100); redki (≥ 1/10.000 do < 1/1.000); zelo redki (< 1/10.000), neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
English: Talk to your doctor before taking Actelsar HCT if you are suffering or have ever suffered from any of the following conditions or illnesses:
Slovenian: Pred začetkom jemanja zdravila Actelsar HCT obvestite zdravnika, če imate ali ste kadar koli imeli katero koli od naslednjih bolezenskih stanj ali bolezni:
English: Lupus-like syndrome, photosensitivity reactions, skin vasculitis, toxic epidermal necrolysis, erythema multiforme
Slovenian: lupusu podoben sindrom, fotosenzibilne reakcije, kožni vaskulitis, toksična epidermalna nekroliza, multiformni eritem
English: Experience with telmisartan/hydrochlorothiazide is modest in the patients with mild to moderate renal impairment, therefore periodic monitoring of potassium, creatinine and uric acid serum levels is recommended.
Slovenian: S kombinacijo telmisartan/hidroklorotiazid je malo izkušenj pri bolnikih z blago do zmerno zmanjšanim delovanjem ledvic, zato so priporočljivi periodični kontrolni pregledi serumskih ravni kalija, kreatinina in sečne kisline.
English: Hydrochlorothiazide is excreted almost entirely as unchanged substance in urine.
Slovenian: Hidroklorotiazidse skoraj v celoti izloči v obliki nespremenjene učinkovine s sečem.
English: Actelsar HCT is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not controlled enough when telmisartan is used alone.
Slovenian: Zdravilo Actelsar HCT je namenjeno za zdravljenje visokega krvnega tlaka (esencialne hipertenzije) pri odraslih, pri katerih s samim telmisartanom krvnega tlaka ne moremo dovolj uravnati.
English: What Actelsar HCT is and what it is used for What you need to know before you take Actelsar HCT How to take Actelsar HCT
Slovenian: Kaj je zdravilo Actelsar HCT in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Actelsar HCT Kako jemati zdravilo Actelsar HCT Možni neželeni učinki
English: The absolute bioavailability of telmisartan at 40 mg and 160 mg was 42% and 58%, respectively.
Slovenian: Njegova absolutna biološka uporabnost je bila po dajanju odmerkov po 40 mg in 160 mg 42- oz. 58-odstotna.
English: Anorexia, appetite decreased, electrolyte imbalance, hypercholesterolaemia, hyperglycaemia, hypovolaemia
Slovenian: anoreksija, zmanjšan apetit, elektrolitsko neravnovesje, hiperholesterolemija, hiperglikemija, hipovolemija
English: Based on modest experience in patients with mild to moderate renal impairment (creatinine clearance of 30-60 ml/min, mean about 50 ml/min) no dose adjustment is necessary in patients with decreased renal function.
Slovenian: Redke izkušnje pri bolnikih z blago do zmerno ledvično okvaro (s kreatininskim očistkom 30 do 60 ml/min in srednjo vrednostjo približno 50 ml/min) kažejo, da bolnikom z zmanjšanim ledvičnim delovanjem odmerka ni treba prilagajati.
English: Telmisartan does not show affinity for other receptors, including AT2 and other less characterised AT receptors.
Slovenian: Telmisartan nima afinitete za druge receptorje, niti za A T2 niti za druge manj raziskane receptorje AT.
English: Some side effects can be serious and need immediate medical attention:
Slovenian: Nekateri neželeni učinki so lahko resni in zahtevajo takojšnjo zdravstveno oskrbo: Nemudoma morate obiskati zdravnika, če se pojavi kateri od naslednjih simptomov:
English: If calcium supplements or calcium sparing medicinal products (e.g. vitamin D therapy) must be prescribed, serum calcium levels should be monitored and calcium dose adjusted accordingly.
Slovenian: Če so kalcijevi nadomestki ali zdravila, ki varčujejo s kalcijem (npr. zdravljenje z vitaminom D), nujno potrebni, je treba spremljati serumsko raven kalcija in njegov odmerek ustrezno prilagoditi.
English: Actelsar HCT may be less effective in lowering the blood pressure in black patients.
Slovenian: Zdravilo Actelsar HCT lahko pri črni rasi manj učinkovito znižuje krvni tlak.
English: How to store Actelsar HCT Contents of the pack and other information
Slovenian: Shranjevanje zdravila Actelsar HCT Vsebina pakiranja in dodatne informacije
English: In patients taking telmisartan alone the following additional side effects have been reported:
Slovenian: Pri bolnikih, ki so jemali samo telmisartan, so poročali še o naslednjih neželenih učinkih:
English: Non-steroidal anti-inflammatory medicinal products (NSAIDs) NSAIDs (i.e. acetylsalicylic acid at anti-inflammatory dose regimens, COX-2 inhibitors and non-selective NSAIDs) may reduce the diuretic, natriuretic and antihypertensive effects of thiazide diuretics and the antihypertensive effects of angiotensin II receptor antagonists.
Slovenian: Nesteroidna protivnetna zdravila (acetilsalicilna kislina v odmerkih, ki učinkujejo protivnetno, zaviralci ciklooksigenaze 2 in neselektivna nesteroidna protivnetna zdravila) lahko zmanjšajo diuretične, natriuretične in antihipertenzivne učinke tiazidnih diuretikov ter antihipertenzivne učinke antagonistov receptorjev angiotenzina II.
English: Sodium starch glycolate (type A) Microcrystalline cellulose Mannitol (E421)
Slovenian: Natrijev karboskimetilškrob (vrsta A) Mikrokristalna celuloza Manitol (E421)
English: Co-administration of lithium and Actelsar HCT is not recommended (see section 4.4).
Slovenian: Sočasno dajanje litija in zdravila Actelsar HCT ne priporočamo (glejte poglavje 4.4).
English: Based on cumulative renal excretion of hydrochlorothiazide the absolute bioavailability was about 60%.
Slovenian: Glede na skupno količino hidroklorotiazida, ki se izloči skozi ledvice, je njegova absolutna biološka uporabnost približno 60-odstotna.
English: The use of HCTZ may also need to be reconsidered in patients who have experienced previous NMSC (see also section 4.8).
Slovenian: Poleg tega bi bilo morda treba ponovno premisliti o uporabi hidroklorotiazida pri bolnikih, ki so že preboleli nemelanomskega kožnega raka (glejte tudi poglavje 4.8).
English: **Cases of progressive scarring of lung tissue have been reported during intake of telmisartan.
Slovenian: **Poročali so o primerih napredujočega brazgotinjenja pljučnega tkiva med jemanjem telmisartana, vendar ni znano, ali je vzrok telmisartan.
English: The toxicological findings observed appear to have no relevance to human therapeutic use.
Slovenian: Kaže, da ugotovitve toksikoloških študij na živalih za terapevtsko uporabo pri človeku niso pomembne.
English: Actelsar HCT tablets are for once-daily oral administration and should be taken with liquid, with or without food.
Slovenian: Jemanje tablet Actelsar HCT je peroralno enkrat na dan s tekočino, s hrano ali brez nje.
English: The other ingredients are magnesium stearate (E470b), potassium hydroxide, meglumine, povidone, sodium starch glycolate (type A), microcrystalline cellulose, mannitol (E421).
Slovenian: - Druge sestavine zdravila so magnezijev stearat (E470b), kalijev hidroksid, meglumin, povidon, natrijev karboskimetilškrob (vrsta A), mikrokristalna celuloza, manitol (E421).
English: Actelsar HCT must not be used in patients with severe renal impairment (creatinine clearance <30 ml/min) (see section 4.3).
Slovenian: Zdravila Actelsar HCT ne smemo dajati bolnikom z močno zmanjšanim delovanjem ledvic (kreatininskim očistkom < 30 ml/min) (glejte poglavje 4.3).
English: You can take Actelsar HCT with or without food.
Slovenian: Zdravilo Actelsar HCT lahko jemljete s hrano ali brez.
English: The diuretic action of hydrochlorothiazide reduces plasma volume, increases plasma renin activity, increases aldosterone secretion, with consequent increases in urinary potassium and bicarbonate loss, and decreases in serum potassium.
Slovenian: Diuretični učinek hidroklorotiazida zmanjša volumen plazme, poveča aktivnost renina v plazmi in izločanje aldosterona, zaradi česar se poveča izguba kalija in hidrogenkarbonata s sečem ter zmanjša količina kalija v serumu.
English: In patients whose vascular tone and renal function depend predominantly on the activity of the reninangiotensin-aldosterone system (e.g. patients with severe congestive heart failure or underlying renal disease, including renal artery stenosis), treatment with medicinal products that affect this system has been associated with acute hypotension, hyperazotaemia, oliguria, or rarely acute renal failure (see section 4.8).
Slovenian: Če sta žilni tonus in ledvično delovanje pretežno odvisna od delovanja renin-angiotenzinaldosteronskega sistema (npr. pri bolnikih s hudim kongestivnim srčnim popuščanjem ali ledvično boleznijo, tudi zožitvijo ledvične arterije), povezujejo zdravljenje z zdravili, katera delujejo na ta sistem, z akutno hipotenzijo, s hiperazotemijo, oligurijo in, redko, z akutno ledvično odpovedjo (glejte poglavje 4.8).
English: - Refractory hypokalaemia, hypercalcaemia.
Slovenian: - Refraktarna hipokaliemija, hiperkalciemija.
English: For Al/Al blisters and HDPE tablet container This medicine does not require any special storage conditions.
Slovenian: Al/Al pretisni omot in HDPE vsebnik za tablete Za shranjevanje zdravila niso potrebna posebna navodila.
English: One study included a population comprised of 71,533 cases of BCC and of 8,629 cases of SCC matched to 1,430,833 and 172,462 population controls, respectively.
Slovenian: Ena od študij je vključevala 71.533 bolnikov z bazalnoceličnim karcinomom in 8.629 bolnikov s ploščatoceličnim karcinomom, ki so jih primerjali s kontrolnim vzorcem 1.430.833 bolnikov z bazalnoceličnim karcinomom in 172.462 bolnikov s ploščatoceličnim karcinomom.
English: • Periodic safety update reports
Slovenian: Periodična poročila o varnosti zdravila
English: Actelsar HCT should not be given to patients with cholestasis, biliary obstructive disorders or severe hepatic insufficiency (see section 4.3) since telmisartan is mostly eliminated with the bile.
Slovenian: Zdravila Actelsar HCT ne smemo dajati bolnikom s holestazo, z obolenji z zaporo žolčevoda ali močno zmanjšanim jetrnim delovanjem (glejte poglavje 4.3), ker se telmisartan v glavnem izloča z žolčem.
English: Medicinal products used in the treatment for gout (e.g. probenecid, sulfinpyrazone and allopurinol) Dose adjustment of uricosuric medicinal products may be necessary as hydrochlorothiazide may raise the level of serum uric acid.
Slovenian: Zdravila za zdravljenje protina (npr. probenecid, sulfinpirazon in alopurinol) Včasih je treba prilagoditi odmerek urikozurikov, ker lahko hidroklorotiazid poveča raven sečne kisline v serumu.
English: Hypokalaemia may result in muscle spasms and/or accentuate arrhythmia associated with the concomitant use of digitalis glycosides or certain anti-arrhythmic medicinal products.
Slovenian: Hipokaliemija lahko povzroči mišične krče in/ali izrazitejšo aritmijo pri sočasnem jemanju digitalisovih glikozidov ali nekaterih antiaritmikov.
English: There is evidence that the concomitant use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren increases the risk of hypotension, hyperkalaemia and decreased renal function (including acute renal failure).
Slovenian: Obstajajo dokazi, da sočasna uporaba zaviralcev ACE, antagonistov receptorjev angiotenzina II ali aliskirena poveča tveganje za hipotenzijo, hiperkaliemijo in zmanjšano delovanje ledvic (vključno z akutno odpovedjo ledvic).
English: The effects of fixed dose combination of telmisartan/HCT on mortality and cardiovascular morbidity are currently unknown.
Slovenian: Učinki fiksne kombinacije telmisartana in hidroklorotiazida na umrljivost in obolevnost zaradi srčnožilnih bolezni še niso raziskani.