FrancophonIA/ELRC3.0 huggingface dataset:
English: The other ingredient is sodium carbonate.
Slovenian: Druga sestavina zdravila je natrijev karbonat.
English: INFORMATION IN BRAILLE <Justification for not including Braille accepted.>
Slovenian: PODATKI V BRAILLOVI PISAVI <Sprejeta je utemeljitev, da Braillova pisava ni potrebna.>
English: The plasma protein binding of meropenem is approximately 2%.
Slovenian: Vezava meropenema na beljakovine v plazmi je približno 2 %.
English: Discontinuation of therapy with Vaborem and the administration of specific treatment for Clostridium difficile should be considered.
Slovenian: V takšnih primerih je treba razmisliti o prenehanju zdravljenja z zdravilom Vaborem in o uvedbi specifičnega zdravljenja okužbe s Clostridium difficile.
English: The colour of the diluted solution is clear to light yellow.
Slovenian: Barva razredčene raztopine je prosojna do svetlo rumena.
English: • Severe allergic reactions that could include sudden swelling of your lips, face, throat or tongue, difficulty swallowing or breathing or a severe rash or other severe skin reactions, or a decrease in blood pressure (which could make you feel faint or dizzy).
Slovenian: • Hude alergijske reakcije, ki lahko vključujejo nenadno oteklost ustnic, obraza, žrela ali jezika, težave pri požiranju ali dihanju ali hud izpuščaj ali druge hude kožne reakcije ali znižanje krvnega tlaka (zaradi česar se lahko počutite slabotni ali omotični).
English: The antimicrobial activity of meropenem has been shown to best correlate with the percent of the dosing interval during which the free meropenem concentrations in plasma exceed the meropenem minimum inhibitory concentration.
Slovenian: Izkazalo se je, da je protimikrobno delovanje meropenema v najboljši korelaciji z odstotkom intervala odmerjanja, med katerim koncentracije prostega meropenema v plazmi presegajo minimalno zaviralno koncentracijo meropenema.
English: Data from in vitro and animal studies suggest that carbapenems may inhibit the hydrolysis of valproic acid's glucuronide metabolite (VPA g) back to valproic acid, thus decreasing the serum concentrations of valproic acid.
Slovenian: Podatki iz študij in vitro in študij na živalih kažejo, da lahko karbapenemi zavirajo hidrolizo glukuronidnega presnovka valprojske kisline (VPA g) nazaj v valprojsko kislino, s čimer se zniža koncentracija valprojske kisline v serumu.
English: Bacteraemia, in association with, or suspected to be associated with, any of the infections listed above
Slovenian: Bakteriemija, ki je povezana ali domnevno povezana s katero koli od zgoraj naštetih okužb
English: Animal studies conducted with meropenem and vaborbactam do not indicate harmful effects with respect to fertility (see section 5.3).
Slovenian: Študije na živalih, opravljene z meropenemom in vaborbaktamom, ne kažejo škodljivih vplivov na plodnost (glejte poglavje 5.3).
English: It may be due to bacteria called Clostridium difficile.
Slovenian: Razlog za to je lahko bakterija Clostridium difficile.
English: The use of Vaborem to treat patients with infections due to bacterial organisms who have limited treatment options is based on pharmacokinetic/pharmacodynamic analyses for meropenem/vaborbactam and on limited data from a randomised clinical trial in which 32 patients were treated with Vaborem and 15 patients were treated with best available therapy for infections caused by carbapenem-resistant organisms (see section 5.1).
Slovenian: Uporaba zdravila Vaborem za zdravljenje bolnikov z bakterijskimi okužbami, ki imajo omejene možnosti zdravljenja, temelji na farmakokinetičnih/farmakodinamičnih analizah meropenema/vaborbaktama in na manjši količini podatkov iz randomiziranega kliničnega preskušanja, v katerem se je 32 bolnikov zdravilo z zdravilom Vaborem, 15 bolnikov pa je prejemalo najboljše razpoložljivo zdravljenje okužb, ki jih povzročajo organizmi, odporni proti karbapenemu (glejte poglavje 5.1).
English: Other medicines and Vaborem Tell your doctor if you are using, have recently used or might use any other medicines.
Slovenian: Obvestite zdravnika, če uporabljate, ste pred kratkim uporabljali ali pa boste morda začeli uporabljati katero koli drugo zdravilo.
English: There are no or limited amount of data (less than 300 pregnancy outcomes) from the use of meropenem/vaborbactam in pregnant women.
Slovenian: Podatkov o uporabi meropenema/vaborbaktama pri nosečnicah ni oziroma so omejeni (manj kot 300 izpostavljenih nosečnosti).
English: Mechanisms of resistance in Gram-negative bacteria that are known to affect meropenem/vaborbactam include organisms that produce metallo-β-lactamases or oxacillinases with carbapenemase activity.
Slovenian: Mehanizmi odpornosti pri gramnegativnih bakterijah, ki znano vplivajo na meropenem/vaborbaktam, vključujejo organizme, ki proizvajajo metalo-β-laktamaze ali oksacilinaze z delovanjem karbapenemaz.
English: Adverse reactions listed in the table with a frequency of “unknown” were not observed in patients participating in trials with Vaborem or meropenem, but have been reported in the post-marketing setting for meropenem alone.
Slovenian: Neželenih učinkov, ki so v preglednici navedeni s pogostnostjo »ni znano«, niso opazili pri bolnikih, ki so sodelovali v preskušanjih zdravila Vaborem ali meropenema, vendar so o njih poročali po začetku trženja pri zdravljenju s samim meropenemom.
English: Carcinogenicity studies have not been conducted with meropenem.
Slovenian: Študij kancerogenosti z meropenemom niso opravili.
English: The steady-state volumes of distribution of meropenem and vaborbactam in patients were 20.2 L and 18.6 L, respectively, following doses of 2 g meropenem/2 g vaborbactam infused over 3 hours every 8 hours, indicating that both compounds distribute into a volume of distribution consistent with the extracellular fluid compartment.
Slovenian: Volumen porazdelitve v stanju dinamičnega ravnovesja je bil 20,2 litra za meropenem in 18,6 litra za vaborbaktam pri bolnikih, ki so dobili 2 g meropenema/2 g vaborbaktama v obliki 3-urne infuzije na vsakih 8 ur, kar je znak, da se obe učinkovini porazdeljujeta z volumnom porazdelitve, ki ustreza predelku z zunajcelično tekočino.
English: Concomitant use with valproic acid/sodium valproate/valpromide
Slovenian: Sočasna uporaba z valprojsko kislino/natrijevim valproatom/valpromidom
English: Patients who have a history of hypersensitivity to carbapenems, penicillins or other beta-lactam antibacterial agents may also be hypersensitive to meropenem/vaborbactam.
Slovenian: Bolniki z anamnezo preobčutljivosti za karbapeneme, peniciline ali druge betalaktamske antibiotike so lahko preobčutljivi tudi za meropenem/vaborbaktam.
English: Intravenous use after reconstitution and dilution
Slovenian: intravenska uporaba po rekonstituciji in razredčitvi
English: ACS Dobfar, S.p.A. Nucleo Industriale S. Atto (loc. S. Nicolo' a Tordino) 64100 Teramo (TE) Italy
Slovenian: Nucleo Industriale S. Atto (loc. S. Nicolo' a Tordino) 64100 Teramo (TE) Italija
English: • you have ever developed severe diarrhoea during or after antibiotic treatment
Slovenian: • ste kdaj med zdravljenjem z antibiotikom ali po njem imeli hudo drisko,
English: The Cmax and AUC of meropenem and vaborbactam are linear across the dose range studied (1 g to 2 g for meropenem and 0.25 g to 2 g for vaborbactam) when administered as a single 3-hour intravenous infusion.
Slovenian: Vrednosti Cmax in AUC meropenema in vaborbaktama so linearne v celotnem preučevanem razponu odmerkov (od 1 g do 2 g za meropenem in od 0,25 g do 2 g za vaborbaktam), če se učinkovini uporabita kot posamezna 3-urna intravenska infuzija.
English: Serious and occasionally fatal hypersensitivity reactions have been reported with meropenem and/or meropenem/vaborbactam (see sections 4.3 and 4.8).
Slovenian: Poročali so o resnih in občasno smrtnih preobčutljivostnih reakcijah na meropenem in/ali kombinacijo meropenema in vaborbaktama (glejte poglavji 4.3 in 4.8).
English: Both meropenem and vaborbactam penetrate into human bronchial epithelial lining fluid (ELF) with concentrations around 65% and 79% of unbound plasma concentrations of meropenem and vaborbactam, respectively.
Slovenian: Meropenem in vaborbaktam pri ljudeh prehajata v bronhialno epitelijsko tekočino (epithelial lining fluidELF) v koncentracijah okoli 65 % oziroma 79 % glede na koncentracije prostega meropenema in vaborbaktama v plazmi.
English: The following adverse reactions have been reported with meropenem alone and/or identified during the Phase 3 trials with Vaborem.
Slovenian: O naslednjih neželenih učinkih so poročali pri zdravljenju s samim meropenemom in/ali so bili ugotovljeni med preskušanji 3. faze z zdravilom Vaborem.
English: Carcinogenicity studies have not been conducted with vaborbactam.
Slovenian: Študij kancerogenosti z vaborbaktamom niso opravili.
English: The medicinal product is supplied in packs of 6 vials.
Slovenian: Zdravilo je na voljo v pakiranjih po 6 vial.
English: The elimination of vaborbactam by the kidneys resulted in high concentrations in the urine.
Slovenian: Izločanje vaborbaktama skozi ledvice je povzročilo visoke koncentracije v urinu.
English: In a population pharmacokinetic analysis there was no effect of gender or race on the pharmacokinetics of meropenem and vaborbactam.
Slovenian: V populacijski farmakokinetični analizi niso ugotovili vpliva spola ali rase na farmakokinetiko meropenema in vaborbaktama.
English: 6.6 Special precautions for disposal and other handling Standard aseptic techniques must be used for solution preparation and administration.
Slovenian: 6.6 Posebni varnostni ukrepi za odstranjevanje in ravnanje z zdravilom Pri pripravi in dajanju raztopine je treba uporabljati standardne aseptične tehnike.
English: Vaborem contains 10.9 mmol (approximately 250 mg) of sodium per vial.
Slovenian: Zdravilo Vaborem vsebuje 10,9 mmol (približno 250 mg) natrija na vialo.
English: Standard aseptic techniques must be used for solution preparation and administration.
Slovenian: Pri pripravi in dajanju raztopine je treba uporabljati standardne aseptične tehnike.
English: • Enterobacter cloacae species complex
Slovenian: • Kompleks vrste Enterobacter cloacae
English: Following dilution, the infusion should be completed within 4 hours when stored at 25° C, or within 22 hours when refrigerated at 2 - 8 °C.
Slovenian: Po razredčitvi je treba infundiranje dokončati v 4 urah, če je raztopina shranjena pri temperaturi 25 °C, ali v 22 urah, če je v hladilniku pri temperaturi 2-8 °C.
English: PHARMACEUTICAL FORM AND CONTENTS Powder for concentrate for solution for infusion 6 vials
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA prašek za koncentrat za raztopino za infundiranje 6 vial
English: The elimination of meropenem by the kidneys resulted in high therapeutic concentrations in urine.
Slovenian: Izločanje meropenema skozi ledvice je povzročilo visoke terapevtske koncentracije v urinu.
English: After mixing gently to dissolve, the reconstituted meropenem/vaborbactam solution will have an approximate meropenem concentration of 0.05 g/ml and an approximate vaborbactam concentration of 0.05 g/ml.
Slovenian: Ko se zdravilo ob previdnem mešanju raztopi, rekonstituirana raztopina meropenema/vaborbaktama vsebuje koncentracijo meropenema približno 0,05 g/ml in koncentracijo vaborbaktama približno 0,05 g/ml.
English: Table 1 shows the recommended intravenous dose for patients with a creatinine clearance (CrCl) ≥40 ml/min (see sections 4.4 and 5.1).
Slovenian: Odmerjanje V preglednici 1 je prikazan priporočeni intravenski odmerek za bolnike z očistkom kreatinina (CrCl) ≥ 40 ml/min (glejte poglavji 4.4 in 5.1).
English: Patients with known seizure disorders should continue anticonvulsant therapy.
Slovenian: Bolniki, pri katerih se znano pojavljajo epileptični napadi, morajo nadaljevati zdravljenje z antikonvulzivi.
English: Caution should be used when administering meropenem/vaborbactam concomitantly with medicinal products with a narrow therapeutic window that are predominantly metabolised by CYP450 enzymes (e.g. immunosuppressants such as tacrolimus, everolimus and cyclosporine, lovastatin, midazolam, sildenafil and warfarin) as conclusive data on whether meropenem or vaborbactam may be inhibitors or inducers of CYP450 enzymes is not yet available.
Slovenian: Pri dajanju meropenema/vaborbaktama sočasno z zdravili z ozkim terapevtskim oknom, ki jih presnavljajo predvsem encimi CYP450 (npr. imunosupresivi, kot so takrolimus, everolimus in ciklosporin, lovastatin, midazolam, sildenafil in varfarin), je potrebna previdnost, saj dokončni podatki o tem, ali sta lahko meropenem ali vaborbaktam zaviralca ali induktorja encimov CYP450, še niso na voljo.
English: Vaborem is administered by intravenous infusion over 3 hours.
Slovenian: Zdravilo Vaborem se daje z intravenskim infundiranjem, ki traja 3 ure.
English: In repeat dose toxicity studies in dogs, minimal hepatic inflammation was observed after 14 days and 28 days of exposure to vaborbactam alone or combined meropenem/vaborbactam.
Slovenian: V študijah toksičnosti ponavljajočih se odmerkov pri psih so po 14 dneh izpostavljenosti samemu vaborbaktamu in po 28 dneh izpostavljenosti kombinaciji meropenema/vaborbaktama opazili minimalno vnetje jeter.
English: SPECIAL STORAGE CONDITIONS Do not store above 25° C.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Ne shranjujte pri temperaturi nad 25 °C.
English: Table 2 shows the recommended dose adjustments for patients with a CrCl ≤39 ml/min.
Slovenian: Okvara ledvic V preglednici 2 so prikazane priporočene prilagoditve odmerka za bolnike s CrCl ≤ 39 ml/min.
English: Co-administration of probenecid with Vaborem is not recommended, as it may result in increased plasma concentrations of meropenem.
Slovenian: Sočasna uporaba probenecida z zdravilom Vaborem ni priporočljiva, saj bi lahko povzročila zvišanje koncentracije meropenema v plazmi.
English: 50 ml clear glass vial (Type 1) closed with a rubber (bromobutyl) stopper and aluminium overseal with flip-off cap.
Slovenian: 50-ml viala iz prozornega stekla (tip 1), zaprta z gumijastim (bromobutilnim) zamaškom in aluminijasto zaporko s snemljivim pokrovčkom.
English: Rare (may affect up to 1 in 1000 people) • Seizures (fits)
Slovenian: Redki (pojavijo se lahko pri največ 1 od 1000 bolnikov) krči (epileptični napadi)
English: Mechanisms of bacterial resistance that could decrease the antibacterial activity of meropenem/vaborbactam include porin mutations affecting outer membrane permeability and overexpression of efflux pumps.
Slovenian: Mehanizmi bakterijske odpornosti, ki lahko zmanjšajo protibakterijsko delovanje meropenema/vaborbaktama, vključujejo mutacije porina, ki vplivajo na prepustnost zunanje membrane in čezmerno ekspresijo izlivnih črpalk.
English: If any of the above apply to you or you are not sure, talk to your doctor or nurse before using Vaborem.
Slovenian: Če kaj od naštetega velja za vas (ali če niste prepričani), se pred uporabo zdravila Vaborem posvetujte z zdravnikom ali medicinsko sestro.
English: The use of Vaborem to treat patients with complicated intra-abdominal infections is based on experience with meropenem alone and pharmacokinetic-pharmacodynamic analyses of meropenem/vaborbactam.
Slovenian: Uporaba zdravila Vaborem za zdravljenje bolnikov z zapletenimi intraabdominalnimi okužbami temelji na izkušnjah s samim meropenemom in na farmakokinetično-farmakodinamičnih analizah meropenema/vaborbaktama.
English: Hospital-acquired pneumonia, including ventilator-associated pneumonia The use of Vaborem to treat patients with hospital-acquired pneumonia, including ventilator-associated pneumonia, is based on experience with meropenem alone and pharmacokinetic-pharmacodynamic analyses for meropenem/vaborbactam.
Slovenian: Bolnišnična pljučnica, vključno z ventilatorsko pljučnico Uporaba zdravila Vaborem za zdravljenje bolnikov s pljučnico, pridobljeno v bolnišnici, vključno z ventilatorsko pljučnico, temelji na izkušnjah s samim meropenemom in na farmakokinetičnofarmakodinamičnih analizah meropenema/vaborbaktama.
English: Simultaneous administration of antibacterial agents with warfarin may augment its anticoagulant effects.
Slovenian: Pri sočasni uporabi protibakterijskih učinkovin se lahko povečajo antikoagulacijski učinki varfarina.
English: Duration in accordance with the site of infection
Slovenian: 3 ure trajanje je odvisno od mesta okužbe
English: • Sudden onset of a severe rash with bullseye-like spots or blistering or peeling skin, possibly with a high fever, joint pain, abnormal function of your liver, kidney or lung (these may be signs of more serious medical conditions called toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme or a condition known as drug reaction with eosinophilia and systemic symptoms (DRESS))
Slovenian: • nenaden pojav hudih izpuščajev, ki so videti kot tarča, ali nastajanje kožnih mehurjev ali lupljenje kože, morda z zelo zvišano telesno temperaturo, bolečinami v sklepih, nenormalnim delovanjem jeter, ledvic ali pljuč (to so lahko znaki resnejših zdravstvenih težav, ki se imenujejo toksična epidermalna nekroliza, Stevens-Johnsonov sindrom in multiformni eritem, ali stanja, ki se imenuje reakcija na zdravilo z eozinofilijo in sistemskimi simptomi (DRESS))
English: Seizures have been reported during treatment with meropenem alone, especially in patients treated with anticonvulsants (see section 4.4).
Slovenian: Med zdravljenjem s samim meropenemom so poročali o epileptičnih napadih, zlasti pri bolnikih, zdravljenih z antikonvulzivi (glejte poglavje 4.4).
English: Pharmacokinetic data from a population pharmacokinetic analysis showed a reduction in plasma clearance of meropenem/vaborbactam that correlates with age-associated reduction in creatinine clearance.
Slovenian: Farmakokinetični podatki iz populacijske farmakokinetične analize so pokazali zmanjšanje plazemskega očistka meropenema/vaborbaktama, ki je v korelaciji z zmanjšanjem očistka kreatinina, povezanim s starostjo.
English: Severe hypersensitivity (e.g. anaphylactic reaction, severe skin reaction) to any other type of beta-lactam antibacterial agent (e.g. penicillins, cephalosporins or monobactams).
Slovenian: Huda preobčutljivost (npr. anafilaktična reakcija, huda kožna reakcija) za kateri koli drug betalaktamski antibiotik (npr. peniciline, cefalosporine ali monobaktame).
English: Efficacy has been demonstrated in clinical studies against the following pathogens that were susceptible to meropenem/vaborbactam in vitro.
Slovenian: V kliničnih študijah je bila dokazana učinkovitost proti naslednjim patogenom, ki so bili in vitro občutljivi za meropenem/vaborbaktam.
English: If administration of Vaborem is necessary, supplemental anticonvulsant therapy should be considered (see section 4.5).
Slovenian: Če je zdravljenje z zdravilom Vaborem potrebno, je treba razmisliti o dodatnem zdravljenju z antikonvulzivi (glejte poglavje 4.5).
English: This is because you may get an abnormal result with something called a “Coombs test”.
Slovenian: Zdravilo lahko namreč povzroči nenormalen rezultat t. i. »Coombsovega testa«.
English: There is no dose adjustment necessary (see section 4.2).
Slovenian: Odmerka ni treba prilagoditi (glejte poglavje 4.2).
English: For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/l.
Slovenian: Za namene testiranja občutljivosti je koncentracija vaborbaktama vedno enaka (8 mg/l).
English: This medicinal product must not be mixed with other medicinal products except those mentioned in section 6.6 of the SmPC.
Slovenian: Zdravila ne smemo mešati z drugimi zdravili razen s tistimi, ki so omenjena v poglavju 6.6 povzetka glavnih značilnosti zdravila.
English: If necessary, the dose of meropenem/vaborbactam should be adjusted based on renal function (see section 4.2).
Slovenian: Po potrebi se odmerek meropenema/vaborbaktama prilagodi glede na delovanje ledvic (glejte poglavje 4.2).
English: • you have ever had a severe allergic reaction to related antibiotics belonging to the beta-lactam group
Slovenian: • ste kdaj imeli hudo alergijsko reakcijo na sorodne antibiotike, ki spadajo v skupino betalaktamov
English: Each vial contains 1 g meropenem (as meropenem trihydrate) and 1 g vaborbactam.
Slovenian: Ena viala vsebuje 1 g meropenema (v obliki meropenem trihidrata) in 1 g vaborbaktama.
English: Both meropenem and vaborbactam are primarily excreted via the kidneys.
Slovenian: Meropenem in vaborbaktam se izločata v glavnem skozi ledvice.
English: The condition can range in severity from mild diarrhoea to fatal colitis and should be considered in patients who present with diarrhoea during or subsequent to the administration of Vaborem (see section 4.8).
Slovenian: Pojavlja se v razponu resnosti od blage diareje do kolitisa s smrtnim izidom, kar je treba upoštevati pri bolnikih, pri katerih se med uporabo zdravila Vaborem ali po njej pojavi diareja (glejte poglavje 4.8).
English: Pseudomonas aeruginosa
Slovenian: Enterobakterije Pseudomonas aeruginosa
English: Reconstitution:
Slovenian: Rekonstitucija:
English: Vaborbactam is a non-beta-lactam inhibitor of class A and class C serine beta-lactamases, including Klebsiella pneumoniae carbapenemase, KPC.
Slovenian: Vaborbaktam je nebetalaktamski zaviralec serinskih betalaktamaz razreda A in razreda C, vključno s karbapenemazo Klebsiella pneumoniae, KPC.
English: Pharmacokinetic studies with meropenem and vaborbactam in patients with renal impairment have shown that the plasma clearance of both meropenem and vaborbactam correlates with creatinine clearance.
Slovenian: Farmakokinetične študije z meropenemom in vaborbaktamom pri bolnikih z okvaro ledvic so pokazale, da sta plazemski očistek meropenema in vaborbaktama v korelaciji z očistkom kreatinina.
English: Clinical efficacy has not been established against the following pathogens that are relevant to the approved indications although in vitro studies suggest that they would be susceptible to meropenem and/or meropenem/vaborbactam in the absence of acquired mechanisms of resistance.
Slovenian: Klinična učinkovitost proti naslednjim patogenom, ki so relevantni za odobrene indikacije, ni bila ugotovljena, vendar študije in vitro kažejo, da bi brez pridobljenih mehanizmov odpornosti ti patogeni bili občutljivi za meropenem in/ali meropenem/vaborbaktam.
English: • Reconstitute 2 vials for the Vaborem 2 g/2 g dose • Reconstitute 1 vial for the Vaborem 1 g/1 g and Vaborem 0.5 g/0.5 g doses
Slovenian: • za odmerek zdravila Vaborem 2 g/2 g rekonstituirajte 2 viali • za odmerek zdravila Vaborem 1 g/1 g ali 0,5 g/0,5 g rekonstituirajte 1 vialo
English: See leaflet for further information.
Slovenian: Za več informacij glejte priloženo navodilo za uporabo.
English: Vaborem 1 g/1 g powder for concentrate for solution for infusion meropenem/vaborbactam
Slovenian: Vaborem 1 g/1 g prašek za koncentrat za raztopino za infundiranje meropenem/vaborbaktam
English: Injury, poisoning and procedural complications
Slovenian: Poškodbe in zastrupitve in zapleti pri posegih reakcija, povezana z infundiranjem
English: Meropenem and vaborbactam can be removed by haemodialysis.
Slovenian: Meropenem in vaborbaktam se lahko odstranita s hemodializo.
English: Before initiating therapy with Vaborem, careful inquiry should be made concerning previous hypersensitivity reactions to beta-lactam antibiotics.
Slovenian: Pred uvedbo zdravljenja z zdravilom Vaborem je treba pozorno preveriti, ali je bolnik v preteklosti imel preobčutljivostne reakcije na betalaktamske antibiotike.
English: The reconstituted solution must be diluted before intravenous infusion.
Slovenian: Pred intravensko infuzijo jo je treba razredčiti.
English: The mean renal clearance for vaborbactam was 10.5 L/h.
Slovenian: Srednji ledvični očistek vaborbaktama je bil 10,5 l/h.
English: 0.5 g/0.5 g
Slovenian: 0,5 g/0,5 g vsakih 12 ur
English: 1 g/1 g
Slovenian: borem 1 g/1