FrancophonIA/ELRC3.0 huggingface dataset:
English: Most of the studies looked at the results separately in patients whose tumours had wildtype KRAS (one of the types of RAS genes) and patients whose tumours had mutated KRAS.
Croatian: Većina je ispitivanja analizirala rezultate zasebno u bolesnika čiji su tumori imali divlji tip KRAS (jedan od tipova RAS gena) i u bolesnika čiji su tumori imali mutirani KRAS.
English: In the studies of cancer of the colon or rectum, Erbitux was shown overall to increase the time patients lived without their cancer getting worse or how long they survived:
Croatian: U ispitivanjima karcinoma kolona ili rektuma, načelno je dokazano da lijek Erbitux produžava vrijeme tijekom kojeg su bolesnici živjeli bez pogoršanja raka ili vrijeme preživljenja:
English: • the first study involved 424 patients with locally advanced cancer, looking at the effects of adding Erbitux to radiotherapy;
Croatian: • prvim su ispitivanjem obuhvaćena 424 bolesnika s lokalno uznapredovanim karcinomom, te je istraženo djelovanje dodavanja lijeka Erbitux u radioterapiju;
English: However, in the third study, patients with wild-type KRAS only survived overall for 16.3 months when Erbitux was added to the another oxaliplatin-based treatment similar to FOLFOX, compared with 18.2 months when the oxaliplatin-based treatment was used alone.
Croatian: No, u trećem ispitivanju, bolesnici samo s KRAS-om divljeg tipa živjeli su ukupno 16,3 mjeseci dulje nakon što je Erbitux dodan drugom liječenju temeljenom na oksaliplatinu koje je slično lijeku FOLFOX, u usporedbi s 18,2 mjeseca u slučaju liječenja kada je korišteno samo liječenje temeljeno na oksaliplatinu.
English: When it is used on its own or with other anticancer medicines, Erbitux is continued for as long as the patient responds.
Croatian: Ako se koristi kao monoterapija ili s drugim antineoplastičkim lijekovima, Erbitux treba nastaviti davati tako dugo dok postoje odgovori bolesnika.
English: Why has Erbitux been approved?
Croatian: Zašto je Erbitux odobren?
English: What is Erbitux?
Croatian: Što je Erbitux?
English: For metastatic cancer of the colon or rectum, Erbitux was studied in six main studies:
Croatian: U slučaju metastatskog karcinoma crijeva ili rektuma, Erbitux se ispitivao u šest glavnih ispitivanja:
English: Erbitux is a solution for infusion (drip into a vein) that contains the active substance cetuximab.
Croatian: Erbitux je otopina za infuziju (drip u venu) koja sadrži djelatnu tvar cetuksimab.
English: In recurrent or metastatic head and neck cancer, survival was longer when Erbitux was added to a platinum-based anticancer medicine combination (10.1 months compared with 7.4 months, on average).
Croatian: U slučaju rekurentnog ili metastatskog karcinoma glave i vrata, preživljenje je bilo duže ako se Erbitux dodao u kombinaciju protutumorskih lijekova baziranih na platini (prosječno 10,1 mjesec u odnosu na 7,4 mjeseci).
English: In patients receiving Erbitux in combination with oxaliplatin-containing chemotherapy (FOLFOX) patients with wild-type RAS lived for longer without their disease getting worse compared with patients on FOLFOX alone (12.0 months compared with 5.8 months, on average).
Croatian: U bolesnika koji su primali lijek Erbitux u kombinaciji s kemoterapijom koja je sadržavala oksaliplatin (FOLFOX), bolesnici s RAS-om divljeg tipa živjeli su dulje, a da se njihova bolest nije pogoršala, u usporedbi s bolesnicima samo na lijeku FOLFOX (prosječno 12,0 mjeseci u usporedbi s 5,8 mjeseci).
English: • the second study involved 442 patients with recurrent or metastatic cancer, looking at the effects of adding Erbitux to a platinum-based anticancer medicine combination.
Croatian: • drugim su ispitivanjem obuhvaćena 442 bolesnika s rekurentnim ili metastatskim karcinomom, te je istraženo djelovanje dodavanja lijeka u Erbitux kombinaciju protutumorskih lijekova baziranih na platini.
English: Patients who had failed both oxaliplatin and irinotecan treatment lived for an average of 3.6 months without their disease getting worse with Erbitux, compared with 1.9 months in those receiving best supportive care alone (the treatment of symptoms but not the cancer itself).
Croatian: Bolesnici kod kojih liječenje oksaliplatinom i irinotekanom nije bilo uspješno živjeli su prosječno 3,6 mjeseci, a da se njihova bolest nije pogoršala, s lijekom Erbitux, u usporedbi s 1,9 mjeseci u bolesnika koji su primali samo najbolju potpornu skrb (liječenje simptoma, no ne i samog karcinoma).
English: • in patients who had not received chemotherapy before, patients who had wild-type KRAS in their tumours lived for longer without their disease getting worse when they received Erbitux in addition to chemotherapy including irinotecan (9.9 months compared with 8.4 months, on average).
Croatian: • u bolesnika koji nisu prethodno primili kemoterapiju, bolesnici koji su imali KRAS divljeg tipa u svojim tumorima živjeli su dulje, a da se njihova bolest nije pogoršala, nakon što su primili lijek Erbitux uz kemoterapiju koja je uključivala irinotekan (prosječno 9,9 mjeseci u usporedbi s 8,4 mjeseci).
English: When RAS genes (such as KRAS) are mutated they can stimulate the tumour cells to grow without being switched on by EGFR, so Erbitux would not be expected to be of much help.
Croatian: KRAS-a) mutiraju, oni mogu stimulirati stanice tumora da rastu, a da ih ne aktivira EGFR, tako da se ne može očekivati velika pomoć od lijeka Erbitux.
English: What benefit has Erbitux shown during the studies?
Croatian: Koje su koristi lijeka Erbitux dokazane u ispitivanjima?
English: In locally advanced head and neck cancers, the patients lived for longer without their disease getting worse when Erbitux was added to radiotherapy (24.4 months compared with 14.9 months, on average).
Croatian: U slučaju karcinoma koji su napredovali lokalno u području glave i vrata, bolesnici su živjeli dulje, a da se njihova bolest nije pogoršala, ako se radioterapiji dodao lijek Erbitux (prosječno 24,4 mjeseca u usporedbi sa 14,9 mjeseci).
English: What is Erbitux used for?
Croatian: Za što se Erbitux koristi?
English: Patients who had failed oxaliplatin treatment lived for an average of 4.0 months without their disease getting worse with Erbitux plus irinotecan, compared with 2.6 months in those receiving irinotecan alone.
Croatian: Bolesnici u kojih liječenje oksaliplatinom nije bilo uspješno živjeli su prosječno 4,0 mjeseci, a da se njihova bolest nije pogoršala, s lijekom Erbitux i irinotekanom, u usporedbi s 2,6 mjeseci u onih koji su primali samo irinotekan.
English: For the full list of all side effects reported with Erbitux, see the package leaflet.
Croatian: Potpuni popis nuspojava zabilježenih pri primjeni lijeka Erbitux potražite u uputi o lijeku.
English: How is Erbitux used?
Croatian: Kako se Erbitux koristi?
English: ‘Metastatic' means that the cancer has spread to other parts of the body.
Croatian: Erbitux se koristi za metastatskog karcinoma crijeva ili rektuma (debelog crijeva). „Metastatski” znači da se karcinom proširio na druge dijelove tijela.
English: How has Erbitux been studied?
Croatian: Kako se Erbitux ispitivao?
English: How does Erbitux work?
Croatian: Kako djeluje Erbitux?
English: • the first study in patients who had taken chemotherapy before did not look at RAS mutations, but in the other two studies, patients with wild-type KRAS in their tumours lived for longer without their disease getting worse when Erbitux was added to their treatment.
Croatian: No, u druga dva ispitivanja bolesnici s KRAS-om divljeg tipa u tumorima živjeli su dulje, a da se njihova bolest nije pogoršala, nakon što je lijek Erbitux dodan njihovom liječenju.
English: United Kingdom Teva Uk Limited
Croatian: Ujedinjeno Kraljevstvo Teva Uk Limited
English: United Kingdom Noridem Enterprises Ltd Sodium Valproate Noridem Enterprises
Croatian: Ujedinjeno Kraljevstvo Noridem Enterprises Ltd Sodium Valproate Noridem Enterprises
English: United Kingdom Norton Healthcare Ltd T/A Ivax
Croatian: Ujedinjeno Kraljevstvo Norton Healthcare Ltd T/A Ivax
English: Valproate Magnesium 10000mg/100 Ml
Croatian: Magnezijev valproat 10000 mg/100 ml
English: Pharma Gmbh Natriumvalproat G.L.
Croatian: G.L. Pharma Gmbh Natriumvalproat G.L.
English: ácido Valpróico Generis Valproic Acid 400mg/4 Ml
Croatian: ácido Valpróico Generis Valproatna kiselina 400 mg/4 ml
English: Pharma Gmbh Convulex Für Kinder
Croatian: G.L. Pharma Gmbh Convulex Für Kinder
English: Valproic Acid 43.38mg/Ml
Croatian: Valproatna kiselina 43,38 mg/ml
English: Capsule, Soft
Croatian: Kapsula, meka
English: Austria sanofi-aventis GmbH Depakine Chrono
Croatian: Austrija sanofi-aventis GmbH Depakine Chrono
English: United Kingdom Winthrop Pharmaceuticals Uk Ltd
Croatian: Ujedinjeno Kraljevstvo Winthrop Pharmaceuticals Uk Ltd
English: Pharma Gmbh Convival Chrono
Croatian: G.L. Pharma Gmbh Convival Chrono
English: Valproate Semisodium 269.1mg Tablet
Croatian: Seminatrijev valproat 269,1 mg tableta
English: Valproic Acid 50mg/Ml
Croatian: Valproatna kiselina 50 mg/ml
English: Powder And Solvent For Solution For Injection
Croatian: Prašak i otapalo za otopinu za injekciju
English: Austria sanofi-aventis GmbH Depakine
Croatian: Austrija sanofi-aventis GmbH Depakine
English: United Kingdom Desitin Arzneimittel Gmbh
Croatian: Ujedinjeno Kraljevstvo Desitin Arzneimittel Gmbh
English: Intravenous Use
Croatian: Intravenska primjena
English: Concentrate For Solution For Injection/Infusion
Croatian: Koncentrat za otopinu za injekciju/infuziju
English: Valproate Semisodium 538.2mg Tablet
Croatian: Seminatrijev valproat 538,2 mg tableta
English: United Kingdom Wockhardt Uk Ltd
Croatian: Ujedinjeno Kraljevstvo Wockhardt Uk Ltd
English: Prolonged-Release Capsule
Croatian: Kapsula s produljenim oslobađanjem
English: Pharma Gmbh Convulex® Retard
Croatian: G.L. Pharma Gmbh Convulex® Retard
English: Valproic Acid 145mg G, Sodium Valproate 333mg G
Croatian: Valproatna kiselina 145 mg G, natrijev valproat 333 mg G
English: United Kingdom Aventis Pharma Ltd Epilim Chrono
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chrono
English: Sodium Valproate Bp 200mg
Croatian: Natrijev valproat BP 200 mg
English: Sodium Valproate Ivax Sodium Valproate 200mg/5 Ml
Croatian: Sodium Valproate Ivax Natrijev valproat 200 mg/5 ml
English: Pharma Gmbh Convulex Cr
Croatian: G.L. Pharma Gmbh Convulex Cr
English: Modified-Release Capsule, Hard
Croatian: Kapsula s prilagođenim oslobađanjem, tvrda
English: Pharma Gmbh Convulex Retard
Croatian: G.L. Pharma Gmbh Convulex Retard
English: Pharma Gmbh Kонвулекс хроно
Croatian: G.L. Pharma Gmbh Kонвулекс хроно
English: Modified-Release Tablet Oral Use
Croatian: Tableta s prilagođenim oslobađanjem
English: Powder And Solvent For Solution For Injection/Infusion
Croatian: Prašak i otapalo za otopinu za injekciju/infuziju
English: Prolonged-Release Granules
Croatian: Granule s produljenim oslobađanjem
English: Prolonged-Release Granules In Sachet
Croatian: Granule s produljenim oslobađanjem u vrećici
English: Valproat Ratiopharm Valproic Acid 145mg G, Sodium Valproate
Croatian: Valproat Ratiopharm Valproatna kiselina 145 mg G, natrijev valproat
English: Valproic Acid 87mg G, Sodium Valproate 200mg Tablet
Croatian: Valproatna kiselina 87 mg G, natrijev valproat 200 mg tableta
English: Valpromide 300mg Tablet
Croatian: Valpromid 300 mg tableta
English: Pharma Gmbh конвулекс хроно
Croatian: G.L. Pharma Gmbh конвулекс хроно
English: United Kingdom Aventis Pharma Ltd Depakote
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Depakote
English: Valproate Magnesium 500mg Tablet
Croatian: Magnezijev valproat 500 mg tableta
English: Pharma Gmbh Convulex
Croatian: G.L. Pharma Gmbh Convulex
English: United Kingdom Aventis Pharma Ltd Epilim
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim
English: Pharma Gmbh конвулекс
Croatian: G.L. Pharma Gmbh конвулекс
English: Natriumvalproaat Teva Valproic Acid 145mg G, Sodium Valproate
Croatian: Natriumvalproaat Teva Valproatna kiselina 145 mg G, natrijev valproat
English: Sodium Valproate 500mg
Croatian: Natrijev valproat 500 mg
English: Sodium Valproate 1000mg Container
Croatian: Natrijev valproat 1000 mg spremnik
English: Sanofi-Aventis Ireland Ltd. T/A SANOFI
Croatian: Sanofi-Aventis Ireland Ltd.
English: Valproic Acid 217.75mg Sachet, Sodium Valproate 500.06mg Sachet
Croatian: Valproatna kiselina 217,75 mg vrećica, natrijev valproat 500,06 mg vrećica
English: Valproate Magnesium 200mg Tablet
Croatian: Magnezijev valproat 200 mg tableta
English: Sodium Valproate 300mg Capsule
Croatian: Natrijev valproat 300 mg kapsula
English: Valproat Neuraxpharm Sodium Valproate 60mg/Ml
Croatian: Valproat Neuraxpharm Natrijev valproat 60 mg/ml
English: Valproic Acid 72.61mg Sachet, Sodium Valproate 166.76mg Sachet
Croatian: Valproatna kiselina 72,61 mg vrećica, natrijev valproat 166,76 mg vrećica
English: Gastro-Resistant Capsule, Hard
Croatian: Želučanootporna kapsula, tvrda
English: Sodium Valproate Teva Sodium Valproate 200mg Tablet
Croatian: Sodium Valproate Teva Natrijev valproat 200 mg tableta
English: Depakine Chrono 500 Valproic Acid 145.14mg Tablet, Sodium
Croatian: Depakine Chrono 500 Valproatna kiselina 145,14 mg tableta, natrijev valproat 333,3 mg tableta
English: Gastro-Resistant Capsule
Croatian: Želučanootporna kapsula
English: Valproic Acid 145.14mg Sachet, Sodium Valproate 333.3mg Sachet
Croatian: Valproatna kiselina 145,14 mg vrećica, natrijev valproat 333,3 mg vrećica
English: Sodium Valproate 200mg
Croatian: Natrijev valproat 200 mg
English: Sodium Valproate 150mg Capsule
Croatian: Natrijev valproat 150 mg kapsula
English: Valproate Semisodium 250mg Tablet
Croatian: Seminatrijev valproat 250 mg tableta
English: Sodium Valproate 500mg Capsule
Croatian: Natrijev valproat 500 mg kapsula
English: Valproate Retard Mylan Sodium Valproate 300mg Tablet
Croatian: Valproate Retard Mylan Natrijev valproat 300 mg tableta
English: Sodium Valproate Teva Sodium Valproate 500mg Tablet
Croatian: Sodium Valproate Teva Natrijev valproat 500 mg tableta
English: Sodium Valproate 400mg Container
Croatian: Natrijev valproat 400 mg spremnik
English: Valproic Acid 290.27mg Sachet, Sodium Valproate 666.6mg Sachet
Croatian: Valproatna kiselina 290,27 mg vrećica, natrijev valproat 666,6 mg vrećica
English: Valproic Acid 29.03mg Sachet, Sodium Valproate 66.66mg Sachet
Croatian: Valproatna kiselina 29.03 mg vrećica, natrijev valproat 66,66 mg vrećica
English: Valproate Retard Mylan Sodium Valproate 500mg Tablet
Croatian: Valproate Retard Mylan Natrijev valproat 500 mg tableta
English: Austria sanofi-aventis GmbH Depakine Chronosphere Valproic Acid 14.51mg Sachet, Sodium
Croatian: Austrija sanofi-aventis GmbH Depakine Chronosphere Valproatna kiselina 14,51 mg vrećica, natrijev valproat 33,33 mg vrećica
English: Austria sanofi-aventis GmbH Depakine Chronosphere Valproic Acid 72.61mg Sachet, Sodium
Croatian: Austrija sanofi-aventis GmbH Depakine Chronosphere Valproatna kiselina 72,61 mg vrećica, natrijev valproat 166,76 mg vrećica
English: Austria sanofi-aventis GmbH Depakine Chronosphere Valproic Acid 145.14mg Sachet, Sodium
Croatian: Austrija sanofi-aventis GmbH Depakine Chronosphere Valproatna kiselina 145,14 mg vrećica, natrijev valproat 333,3 mg vrećica
English: Prolonged-Release Capsule, Hard
Croatian: Kapsula s produljenim oslobađanjem, tvrda
English: Valproat Neuraxpharm Sodium Valproate 300mg/Ml
Croatian: Valproat Neuraxpharm Natrijev valproat 300 mg/ml
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 217.75mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 217,75 mg vrećica, natrijev valproat 500,06 mg vrećica
English: Sanofi-Aventis Aebe Depakine Chronosphere Valproic Acid 29.03mg Sachet, Sodium
Croatian: Sanofi-Aventis Aebe Depakine Chronosphere Valproatna kiselina 29.03 mg vrećica, natrijev valproat 66,66 mg vrećica
English: Depakine Chrono 300 Valproic Acid 87mg Tablet, Sodium
Croatian: Depakine Chrono 300 Valproatna kiselina 87 mg tableta, natrijev valproat 200 mg tableta
English: ácido Valpróico Generis Valproic Acid 87mg Tablet, Sodium
Croatian: ácido Valpróico Generis Valproatna kiselina 87 mg tableta, natrijev valproat 199,8 mg tableta
English: ácido Valproico G.E.S Sodium Valproate 400mg Vial
Croatian: ácido Valproico G.E.S
English: Acido Valproico Sandoz Sodium Valproate 300mg Tablet
Croatian: Acido Valproico Sandoz Natrijev valproat 300 mg tableta
English: Sodium Valproate 500mg Container
Croatian: Natrijev valproat 500 mg spremnik
English: Sodium Valproate 1000mg Sachet
Croatian: Natrijev valproat 1000 mg vrećica
English: ácido Valpróico Sandoz Sodium Valproate 300mg Tablet
Croatian: ácido Valpróico Sandoz Natrijev valproat 300 mg tableta
English: Acido Valproico Sandoz Sodium Valproate 500mg Tablet
Croatian: Acido Valproico Sandoz Natrijev valproat 500 mg tableta
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 14.51mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 14,51 mg vrećica, natrijev valproat 33,33 mg vrećica
English: ácido Valpróico Sandoz Sodium Valproate 500mg Tablet
Croatian: ácido Valpróico Sandoz Natrijev valproat 500 mg tableta
English: Sanofi-Aventis Aebe Depakine Chronosphere Valproic Acid 290.27mg Sachet, Sodium
Croatian: Sanofi-Aventis Aebe Depakine Chronosphere Valproatna kiselina 290,27 mg vrećica, natrijev valproat 666,6 mg vrećica
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 29.03mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 29.03 mg vrećica, natrijev valproat 66,66 mg vrećica
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 145.14mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 145,14 mg vrećica, natrijev valproat 333,3 mg vrećica
English: Sanofi-Aventis Aebe Depakine Chronosphere Valproic Acid 72.61mg Sachet, Sodium
Croatian: Sanofi-Aventis Aebe Depakine Chronosphere Valproatna kiselina 72,61 mg vrećica, natrijev valproat 166,76 mg vrećica
English: Valproat 1 A Pharma Sodium Valproate 300mg Tablet
Croatian: Valproat 1 A Pharma Natrijev valproat 300 mg tableta
English: Valproat Chrono Sandoz Sodium Valproate 300mg Tablet
Croatian: Valproat Chrono Sandoz Natrijev valproat 300 mg tableta
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 72.61mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 72,61 mg vrećica, natrijev valproat 166,76 mg vrećica
English: Valproat Chrono Sandoz Sodium Valproate 500mg Tablet
Croatian: Valproat Chrono Sandoz Natrijev valproat 500 mg tableta
English: Espa-Valept Retard Sodium Valproate 300mg Tablet
Croatian: Espa-Valept Retard Natrijev valproat 300 mg tableta
English: Valproat 1 A Pharma Sodium Valproate 500mg Tablet
Croatian: Valproat 1 A Pharma Natrijev valproat 500 mg tableta
English: Oral Drops, Solution Oral Use
Croatian: Oralne kapi, otopina Kroz usta
English: Valproát Chrono Sandoz Sodium Valproate 500mg Tablet
Croatian: Valproát Chrono Sandoz Natrijev valproat 500 mg tableta
English: Valproat Neuraxpharm Sodium Valproate 150mg Units
Croatian: Valproat Neuraxpharm Natrijev valproat 150 mg jedinica
English: Valproat 1 A Pharma Sodium Valproate 600mg Tablet
Croatian: Valproat 1 A Pharma Natrijev valproat 600 mg tableta
English: Valproát Chrono Sandoz Sodium Valproate 300mg Tablet
Croatian: Valproát Chrono Sandoz Natrijev valproat 300 mg tableta
English: Valproat Neuraxpharm Sodium Valproate 600mg Units
Croatian: Valproat Neuraxpharm Natrijev valproat 600 mg jedinica
English: Valproate Retard Eg Valproic Acid 87mg Tablet, Sodium
Croatian: Eurogenerics N.V./S.A. Valproate Retard Eg Valproatna kiselina 87 mg tableta, natrijev valproat 199,8 mg tableta
English: ácido Valpróico Generis Valproic Acid 145mg Tablet, Sodium
Croatian: ácido Valpróico Generis Valproatna kiselina 145 mg tableta, natrijev valproat 333 mg tableta
English: Valproat 1 A Pharma Sodium Valproate 150mg Tablet
Croatian: Valproat 1 A Pharma Natrijev valproat 150 mg/ml tableta
English: United Kingdom Aventis Pharma Ltd Epilim Chronosphere Valproic Acid 290.27mg Sachet, Sodium
Croatian: Ujedinjeno Kraljevstvo Aventis Pharma Ltd Epilim Chronosphere Valproatna kiselina 290,27 mg vrećica, natrijev valproat 666,6 mg vrećica
English: Valproat Neuraxpharm Sodium Valproate 500mg Units
Croatian: Valproat Neuraxpharm Natrijev valproat 500 mg jedinica
English: Valproat Neuraxpharm Sodium Valproate 300mg Units
Croatian: Valproat Neuraxpharm Natrijev valproat 300 mg jedinica
English: Depakine Chronosphere Valproic Acid 217.75mg Sachet, Sodium
Croatian: Depakine Chronosphere Valproatna kiselina 217,75 mg vrećica, natrijev valproat 500,06 mg vrećica
English: Pharma Gmbh Epival Cr
Croatian: Ujedinjeno Kraljevstvo G.L. Pharma Gmbh Epival Cr
English: Sodium Valproate 400mg Vial
Croatian: Natrijev valproat 400 mg bočica
English: Sodium Valproate 300mg Suppository
Croatian: Natrijev valproat 300 mg čepić
English: Valproate Semisodium 500mg Tablet
Croatian: Seminatrijev valproat 500 mg tableta
English: Depakine Chronosphere Valproic Acid 14.51mg Sachet, Sodium
Croatian: Depakine Chronosphere Valproatna kiselina 14,51 mg vrećica, natrijev valproat 33,33 mg vrećica
English: Gastro-Resistant Capsule, Soft
Croatian: Želučanootporna kapsula, meka
English: Valproate Retard Eg Valproic Acid 145mg Tablet, Sodium
Croatian: Eurogenerics N.V./S.A. Valproate Retard Eg Valproatna kiselina 145 mg tableta, natrijev valproat 333 mg tableta
English: Sodium Valproate 500mg Sachet
Croatian: Natrijev valproat 500 mg vrećica
English: Ucedane carglumic acid
Croatian: Ucedane karglumatna kiselina
English: The initial daily dose of Ucedane should be 100 mg per kilogram body weight, but up to 250 mg/kg can be used if necessary.
Croatian: Početna doza lijeka Ucedane treba biti 100 mg po kilogramu tjelesne težine, ali ako je potrebno može se primijeniti do 250 mg/kg.
English: The full EPAR for Ucedane can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Croatian: Cjeloviti EPAR za lijek Ucedane nalazi se na internetskim stranicama Agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: What is Ucedane and what is it used for?
Croatian: Što je Ucedane i za što se koristi?
English: Treatment may be started as early as the first day of life and the medicine is used for the patient's whole life.
Croatian: S liječenjem se može započeti već prvog dana života, a lijek se uzima tijekom cijelog života bolesnika.
English: When ammonia builds up in the blood, it is toxic to the body, especially the brain.
Croatian: Kada se amonijak nakuplja u krvi, toksičan je za tijelo, a osobito mozak.
English: What measures are being taken to ensure the safe and effective use of Ucedane?
Croatian: Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena lijeka Ucedane?
English: Two medicines are bioequivalent when they produce the same levels of the active substance in the body and are therefore expected to have the same effect.
Croatian: Dva su lijeka bioekvivalentna ako proizvode jednake razine djelatne tvari u tijelu pa se stoga očekuje da imaju jednak učinak.
English: If the enzyme is not present, ammonia cannot be broken down and it builds up in the blood.
Croatian: Ako ovaj enzim nije prisutan, amonijak se ne može razgraditi i nakuplja se u krvi.
English: The dose should then be adjusted to maintain normal blood ammonia levels.
Croatian: Dozu zatim treba prilagoditi kako bi se održavale normalne razine amonijaka u krvi.
English: Ucedane is available as dispersible tablets (200 mg) that are to be dispersed (mixed) in a small amount of water.
Croatian: Ucedane je dostupan u obliku tableta za oralnu suspenziju (200 mg) koje treba rastopiti (izmiješati) u malo vode.
English: The medicine can only be obtained with a prescription and treatment should be started by a doctor who has experience in treating patients with metabolic diseases such as NAGS deficiency.
Croatian: Lijek se izdaje samo na recept, a liječenje treba započeti liječnik s iskustvom u liječenju bolesnika s metaboličkim bolestima kao što je manjak NAGS-a.