FrancophonIA/ELRC3.0 huggingface dataset:
English: Appropriate aseptic technique should be used for reconstitution and dilution procedures.
Croatian: Tijekom postupaka rekonstitucije i razrjeđivanja potrebno je primijeniti odgovarajuću aseptičku tehniku.
English: The data also suggested that the pharmacokinetics of cisplatin were not affected by concurrent use of capecitabine or by concurrent use of capecitabine plus trastuzumab.
Croatian: Podaci su također ukazali da istodobna primjena kapecitabina ili istodobna primjena kapecitabina i trastuzumaba ne utječe na farmakokinetiku cisplatina.
English: Hazard Ratio vs AC→D (95% CI)
Croatian: Omjer hazarda naspram AC→D (95% CI)
English: KANJINTI 420 mg powder for concentrate for solution for infusion
Croatian: KANJINTI 420 mg prašak za koncentrat za otopinu za infuziju
English: neck pain haemorrhoids bone pain itchiness acne leg cramps
Croatian: bol u vratu hemoroidi bol u kostima svrbež akne grčevi u nogama
English: Pulmonary events
Croatian: Plućne reakcije
English: Trastuzumab may persist in the circulation for up to 7 months after stopping KANJINTI treatment based on population pharmacokinetic analysis of all available data (see section 5.2).
Croatian: Na temelju populacijske farmakokinetičke analize svih dostupnih podataka (vidjeti dio 5.2), trastuzumab može biti prisutan u cirkulaciji do 7 mjeseci nakon prestanka liječenja lijekom KANJINTI.
English: This yields a 7.4 mL solution for single-dose use, containing approximately 21 mg/mL trastuzumab, at a pH of approximately 6.1.
Croatian: Time se dobiva 7,4 ml otopine za jednokratnu primjenu, koja sadrži približno 21 mg/ml trastuzumaba, s pH vrijednošću od približno 6,1.
English: The recommended weekly maintenance dose of KANJINTI is 2 mg/kg body weight, beginning one week after the loading dose.
Croatian: Preporučena doza održavanja lijeka KANJINTI koja se primjenjuje u tjednim intervalima iznosi 2 mg/kg tjelesne težine, a počinje se primjenjivati tjedan dana nakon udarne doze.
English: 2+ A weak to moderate complete membrane staining is detected in > 10% of the tumour cells.
Croatian: Slaba do umjerena obojenost cijele membrane u > 10% tumorskih stanica.
English: This yields a 21 mL solution for single-dose use, containing approximately 21 mg/mL trastuzumab, at a pH of approximately 6.1.
Croatian: Time se dobiva 21 ml otopine za jednokratnu primjenu, koja sadrži približno 21 mg/ml trastuzumaba, s pH vrijednošću od približno 6,1.
English: KANJINTI 150 mg powder for concentrate for solution for infusion
Croatian: KANJINTI 150 mg prašak za koncentrat za otopinu za infuziju
English: Table 14 Population predicted cycle 1 PK exposure values (median with 5th - 95th percentiles) for trastuzumab intravenous dosing regimens in MBC, EBC and AGC patients
Croatian: Vrijednosti farmakokinetičke izloženosti predviđene za populaciju u 1. ciklusu (medijan i 5. do 95. percentil) uz režime doziranja intravenske formulacije trastuzumaba u bolesnika s metastatskim rakom dojke, ranim rakom dojke i uznapredovalim rakom želuca
English: Detection of HER2 over expression or HER2 gene amplification in gastric cancer Only an accurate and validated assay should be used to detect HER2 over expression or HER2 gene amplification.
Croatian: Za otkrivanje pojačane ekspresije HER2 ili HER2 genske amplifikacije potrebno je primjenjivati samo precizne i validirane metode.
English: The recommended maintenance dose at three-weekly intervals is 6 mg/kg body weight, beginning three weeks after the loading dose.
Croatian: Preporučena doza održavanja koja se primjenjuje u trotjednim intervalima iznosi 6 mg/kg tjelesne težine, a počinje se primjenjivati 3 tjedna nakon početne doze.
English: 3+ Strong complete membrane staining is detected in > 10% of the tumour cells.
Croatian: Jaka obojenost cijele membrane otkrivena u > 10% tumorskih stanica.
English: Mucosal inflammation
Croatian: • zatajenje bubrega
English: Ear and labyrinth disorders
Croatian: Poremećaji uha i labirinta gluhoća manje često
English: Disease-free survival - No. patients with event - No. patients without event P-value versus Observation Hazard Ratio versus Observation Recurrence-free survival - No. patients with event - No. patients without event P-value versus Observation Hazard Ratio versus Observation Distant disease-free survival - No. patients with event - No. patients without event P-value versus Observation Hazard Ratio versus Observation Overall survival (death) - No. patients with event - No. patients without event P-value versus Observation Hazard Ratio versus Observation
Croatian: Preživljenje bez povrata bolesti - broj bolesnica s događajem - broj bolesnica bez događaja P-vrijednost naspram opservacije Omjer hazarda naspram opservacije
English: Hepatitis
Croatian: Hematotoksičnost
English: Pulmonary hypoplasia
Croatian: • mišićna slabost
English: t1/2 range from
Croatian: Raspon t1/2 od Cmax,ss do
English: The recommended maintenance dose of KANJINTI at three-weekly intervals is 6 mg/kg body weight, beginning three weeks after the loading dose.
Croatian: Preporučena doza održavanja lijeka KANJINTI koja se primjenjuje u trotjednim intervalima iznosi 6 mg/kg tjelesne težine, a počinje se primjenjivati 3 tjedna nakon udarne doze.
English: • respiratory failure
Croatian: • nedostatak zraka
English: 4 mg/kg + 2 mg/kg qw
Croatian: 4 mg/kg + 2 mg/kg jedanput na tjedan metastatski rak dojke 805
English: How KANJINTI is given
Croatian: Kako čuvati KANJINTI
English: • tremor
Croatian: • umor
English: Distant recurrence No. patients with event p < 0.0001
Croatian: Pojava udaljenih metastaza broj bolesnica s događajem p < 0,0001
English: Event-free survival No. patients with event
Croatian: Preživljenje bez štetnih događaja Broj bolesnica s događajem
English: Febrile neutropenia
Croatian: • nevoljno drhtanje
English: This medicinal product must not be mixed or diluted with other medicinal products except those mentioned under section 6.6.
Croatian: Ovaj lijek se ne smije miješati ni razrjeđivati s drugim lijekovima, osim onih navedenih u dijelu 6.6. KANJINTI se ne smije razrjeđivati s otopinama glukoze jer izazivaju taloženje proteina.
English: Onychoclasis
Croatian: Nuspojava
English: Trastuzumab washout period was assessed following q1w or q3w intravenous administration using the population PK model.
Croatian: Razdoblje ispiranja trastuzumaba ocijenjeno je nakon intravenske primjene lijeka jedanput na tjedan ili jedanput svaka 3 tjedna uz pomoć populacijskog farmakokinetičkog modela.
English: The median overall survival for the high HER2 expressing group was 11.8 months versus 16 months, HR 0.65 (95% CI 0.51-0.83) and the median progression free survival was 5.5 months versus 7.6 months, HR 0.64 (95% CI 0.51-0.79) for FP versus FP + H, respectively.
Croatian: Medijan ukupnog preživljenja u skupini s visokom ekspresijom HER2 koja nije primala trastuzumab iznosio je 11,8 mjeseci u usporedbi sa 16 mjeseci u skupini koja je primala trastuzumab, omjer hazarda (HR) 0,65 (95% CI 0,51-0,83).
English: • runny nose
Croatian: • curenje iz nosa
English: • capecitabine - 1,000 mg/m2 orally twice daily for 14 days every 3 weeks for 6 cycles (evening of day 1 to morning of day 15 of each cycle)
Croatian: Kemoterapija je primjenjivana na sljedeći način: - kapecitabin - 1000 mg/m2 peroralno, dvaput dnevno, tijekom 14 dana svaka 3 tjedna u 6 ciklusa
English: or - intravenous paclitaxel - 175 mg/m2 as a continuous intravenous infusion, given every 3 weeks for 4 cycles (day 1 of each cycle).
Croatian: ili - intravenski paklitaksel - 175 mg/m2 u kontinuiranoj intravenskoj infuziji svaka 3 tjedna u 4
English: +Respiratory distress
Croatian: • zatajenje disanja
English: Time to disease progression, Median months
Croatian: Preživljenje bez napredovanja bolesti, medijan u mjesecima Vrijeme do progresije bolesti, medijan u mjesecima Stopa ukupnog odgovora na liječenje, %
English: Hazard Ratio versus AC→P (95% CI)
Croatian: Omjer hazarda naspram AC→P (95% CI)
English: Disease-free survival No. patients with event p < 0.0001
Croatian: Preživljenje bez bolesti broj bolesnica s događajem p < 0,0001
English: The recommended scoring system to evaluate the IHC staining patterns is as stated in table 3: Table 3 Recommended scoring system to evaluate the IHC staining patterns in gastric cancer Score Surgical specimen - staining pattern
Croatian: Tablica 3. Preporučena ljestvica vrednovanja rezultata bojanja preparata po IHC metodi u raku želuca
English: Breast inflammation/mastitis
Croatian: Poremećaji reproduktivnog sustava i dojki upala dojke/mastitis često
English: • deafness
Croatian: • omaglica
English: MBC EBC Table 15 Population predicted steady-state PK exposure values (median with 5th - 95th percentiles) for trastuzumab intravenous dosing regimens in MBC, EBC and AGC patients
Croatian: Vrijednosti farmakokinetičke izloženosti u stanju dinamičke ravnoteže predviđene za populaciju (medijan i 5. do 95. percentil) uz režime doziranja intravenske formulacije trastuzumaba u bolesnika s metastatskim rakom dojke, ranim rakom dojke i uznapredovalim rakom želuca
English: Patients with MBC or MGC should be treated with KANJINTI until progression of disease.
Croatian: U bolesnika s metastatskim rakom dojke ili metastatskim rakom želuca liječenje lijekom KANJINTI traje do progresije bolesti.
English: Hazard Ratio vs AC→P (95% CI) p-value
Croatian: Omjer hazarda naspram AC→P (95% CI) p-vrijednost
English: Cmax,ss to Cmin,ss
Croatian: Cmin,ss
English: PHARMACEUTICAL FORM AND CONTENTS Powder for concentrate for solution for infusion
Croatian: Prašak za koncentrat za otopinu za infuziju
English: Parenteral medicinal products should be inspected visually for particulate matter and discolouration prior to administration.
Croatian: Prije primjene, parenteralne lijekove treba pregledati zbog mogućih zaostalih čestica ili promjene boje.
English: • fatigue
Croatian: • mučnina
English: • high potassium levels
Croatian: • visoke razine kalija
English: Urticaria
Croatian: Sljedivost
English: Severe pulmonary adverse reactions occur in association with the use of trastuzumab and have been associated with a fatal outcome.
Croatian: Pri primjeni trastuzumaba uočene su teške plućne nuspojave koje su završavale smrtnim ishodom.
English: NAME OF THE MEDICINAL PRODUCT KANJINTI 420 mg powder for concentrate for solution for infusion trastuzumab
Croatian: KANJINTI 420 mg prašak za koncentrat za otopinu za infuziju trastuzumab
English: Signs and symptoms of cardiac dysfunction such as dyspnoea, orthopnoea, increased cough, pulmonary oedema, S3 gallop, or reduced ventricular ejection fraction, have been observed in patients treated with trastuzumab (see section 4.4).
Croatian: U bolesnika liječenih trastuzumabom primijećeni su znakovi i simptomi disfunkcije srca, poput dispneje, ortopneje, pojačanog kašlja, plućnog edema, trećeg srčanog zvuka ili smanjene ejekcijske frakcije klijetke (vidjeti dio 4.4).
English: - following adjuvant chemotherapy with doxorubicin and cyclophosphamide, in combination with paclitaxel or docetaxel.
Croatian: Primjena u kombinaciji s paklitakselom ili docetakselom
English: Ataxia
Croatian: Doziranje
English: +1Wheezing
Croatian: +1piskanje vrlo često
English: ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS
Croatian: Rezultat Karakteristika obojenja
English: Table 16 Population predicted PK parameter values at steady-state for trastuzumab intravenous dosing regimens in MBC, EBC and AGC patients
Croatian: Vrijednosti farmakokinetičkih parametara u stanju dinamičke ravnoteže predviđene za populaciju uz režime doziranja intravenske formulacije trastuzumaba u bolesnika s metastatskim rakom dojke, ranim rakom dojke i uznapredovalim rakom želuca
English: Papilloedema
Croatian: Imunogenost
English: NAME OF THE MEDICINAL PRODUCT KANJINTI 150 mg powder for concentrate for solution for infusion trastuzumab
Croatian: KANJINTI 150 mg prašak za koncentrat za otopinu za infuziju trastuzumab
English: - in combination with paclitaxel for the treatment of those patients who have not received chemotherapy for their metastatic disease and for whom an anthracycline is not suitable.
Croatian: U bolesnika s pozitivnim hormonskim receptorima indiciran je u slučaju progresije na provedenu hormonsku terapiju, što ne vrijedi za bolesnike koji nisu bili pogodni za hormonsko liječenje. - u kombinaciji s paklitakselom u liječenju bolesnika koji prethodno nisu primali kemoterapiju za metastatsku bolest i onih koji nisu pogodni za liječenje antraciklinom.
English: • dizziness
Croatian: • gluhoća
English: AC→DH (n = 1074) Hazard Ratio vs AC→D (95% CI) p-value
Croatian: Omjer hazarda naspram AC→D (95% CI) p-vrijednost
English: +Hypoxia
Croatian: +hipoksija nepoznato
English: • bruising
Croatian: • proljev
English: Immune system disorders
Croatian: Poremećaji imunološkog sustava preosjetljivost često
English: KANJINTI and anthracyclines should not be given concurrently in combination in the MBC setting.
Croatian: Kod liječenja metastatskog raka dojke ne smiju se istodobno davati KANJINTI i antraciklini.
English: Therefore you should tell your doctor, pharmacist or nurse that you have had KANJINTI if you start any new medicine in the 7 months after stopping treatment.
Croatian: Ako započnete uzimanje bilo kojeg novog lijeka tijekom 7 mjeseci nakon prestanka terapije lijekom KANJINTI, recite svom liječniku, ljekarniku ili medicinskoj sestri da ste primali KANJINTI.
English: The median duration of follow-up was 1.8 years for the patients in the AC→P arm and 2.0 years for patients in the AC→PH arm. Table 7 Summary of efficacy results from the joint analysis of the NSABP B-31 and NCCTG N9831 trials at the time of the definitive DFS analysis*
Croatian: Medijan trajanja praćenja iznosio je 1,8 godina za bolesnice u skupini koja je primila AC→P kemoterapiju i 2,0 godine za bolesnice u skupini koja je primala AC→PH kemoterapiju.
English: Parenteral solutions should be inspected visually for particulates and discolouration prior to administration.
Croatian: Parenteralnu otopinu prije davanja treba pregledati zbog mogućih zaostalih čestica ili promjene boje.
English: Early breast cancer
Croatian: Rani rak dojke
English: +Bronchospasm
Croatian: • uzdignuti osip
English: Nail disorder
Croatian: Prijavljivanje nuspojava
English: Death (OS event) No. patients with event p < 0.0001
Croatian: Smrt (događaj ukupnog preživljenja): broj bolesnica s događajem p = 0,014**
English: Adopted at the 6-9 February 2017 PRAC
Croatian: Usvojeno na sjednici PRAC-a 6.-9. veljače 2017.
English: Undesirable effects e Rash is a composite term which includes maculopapular rash, rash erythematous, rash pruritic, rash follicular, rash macular, rash morbilliform, rash papular, rash pustular, rash papulosquamous, rash vesicular, rash generalised, dermatitis, dermatitis acneiform, dermatitis allergic, dermatitis atopic, dermatitis bullous, dermatitis exfoliative, dermatitis psoriasiform, and drug eruption and pemphigoid.
Croatian: Nuspojave e Osip je kompozitni pojam koji uključuje makulopapularni osip, eritematozni osip, pruritički osip, folikularni osip, makularni osip, morbiliformni osip, papularni osip, pustularni osip, papuloskvamozni osip, vezikularni osip, generalizirani osip, dermatitis, akneiformni dermatitis, alergijski dermatitis, atopijski dermatitis, bulozni dermatitis, eksfolijativni dermatitis, psorijaziformni dermatitis, i izbijanje kožnih promjena uzrokovano lijekom i pemfigoid.
English: Nivolumab - Pemphigoid (EPITT no 18759)
Croatian: Nivolumab - pemfigoid (EPITT br. 18759)
English: The relationship between fluconazole use and these events is unclear.
Croatian: Nije jasna povezanost između primjene flukonazola i tih anomalija.
English: An observational study has suggested an increased risk of spontaneous abortion in women treated with fluconazole during the first trimester.
Croatian: Opservacijsko ispitivanje ukazalo je na povećani rizik od spontanog pobačaja kod žena liječenih flukonazolom tijekom prvog tromjesečja.
English: There have been reports of multiple congenital abnormalities (including brachycephalia, ears dysplasia, giant anterior fontanelle, femoral bowing and radio-humeral synostosis) in infants whose mothers were treated for at least three or more months with high doses (400-800 mg daily) of fluconazole for coccidioidomycosis.
Croatian: Postoje izvješća o višestrukim kongenitalnim anomalijama (uključujući brahicefaliju, displaziju ušiju, divovsku prednju fontanelu, iskrivljenje femura i sinostozu ramene i palčane kosti) u novorođenčadi čije su majke liječene visokim dozama flukonazola (400 - 800 mg dnevno) tijekom najmanje tri ili više mjeseci zbog kokcidioidomikoze.
English: Data from several hundred pregnant women treated with standard doses (<200 mg/day) of fluconazole, administered as a single or repeated dose in the first trimester, show no increased risk of undesirable effects in the foetus.
Croatian: Podaci od nekoliko stotina trudnica liječenih standardnim dozama(<200 mg/dan) flukonazola, primijenjenima kao jednokratne ili opetovane doze u prvom tromjesečju trudnoće, nisu pokazali povećan rizik od nuspojava kod fetusa.
English: Fluconazole in standard doses and short-term treatments should not be used in pregnancy unless clearly necessary.
Croatian: Flukonazol se u standardnim dozama i za kratkotrajno liječenje ne smije koristiti u trudnoći, osim ako je to neophodno.
English: New product information wording - Extracts from PRAC recommendations on signals EMA/PRAC/68687/2017
Croatian: Novi tekst informacija o lijeku - izvadci iz preporuka PRAC-a vezanih uz signale EMA/PRAC/115779/2017
English: 4 - Possible side effects Skin rash sometimes with blisters, itching
Croatian: Osip kože ponekad sa mjehurićima, praćen svrbežom
English: Fluconazole in high dose and/or in prolonged regimens should not be used during pregnancy except for potentially life-threatening infections.
Croatian: Flukonazol se u visokim dozama i/ili za dugotrajno liječenje ne smije se koristiti u trudnoći, osim za infekcije koje mogu biti opasne po život.
English: Fluconazole - Spontaneous abortion and stillbirth (EPITT no 18666)
Croatian: Flukonazol - spontani pobačaj i mrtvorođenje (EPITT br.
English: Package leaflet
Croatian: 4 - Moguće nuspojave
English: Water may be given.
Croatian: Može im se dati voda.
English: The expiry date refers to the last day of that month.
Croatian: Rok isteka valjanosti odnosi se na posljednji dan toga mjeseca.
English: If symptoms occur, seek the advice of a physician.
Croatian: U slučaju pojave simptoma, potražiti savjet liječnika.
English: Spontaneous recovery occurs within 3 hours.
Croatian: Do spontanog oporavka dolazi unutar 3 sata.
English: The following doses are recommended:
Croatian: Preporučene su sljedeće doze:
English: The veterinary medicinal product is intended for:
Croatian: Ovaj veterinarsko-medicinski proizvod namijenjen je za:
English: The stopper may be safely punctured up to 100 times.
Croatian: Čep se može sigurno probušiti do najviše 100 puta.
English: Sympathetic neurotransmission is prevented and the level of consciousness decreases.
Croatian: Simpatička neurotransmisija se sprječava, a stupanj svijesti se smanjuje.
English: The corresponding doses based on body weight are presented in the following tables.
Croatian: Odgovarajuće doze zasnovane na tjelesnoj težini prikazane su u sljedećim tablicama.
English: These measures should help to protect the environment.
Croatian: Te mjere pomažu u očuvanju okoliša.
English: At maximal effect, the animal is relaxed, recumbent and does not respond to external stimulus.
Croatian: Pri maksimalnom učinku životinja je opuštena i ne reagira na vanjske podražaje.
English: Dosing for cats is presented in the following table.
Croatian: Doziranje za mačke prikazano je u sljedećoj tablici.
English: Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (http://www.ema.europa.eu/).
Croatian: Detaljne informacije o ovome veterinarsko-medicinskom proizvodu dostupne su na mrežnoj stranici Europske agencije za lijekove (http://www.ema.europa.eu/).
English: Some dogs and cats may also vomit at the time of recovery.
Croatian: Neki psi i mačke mogu povraćati i tijekom oporavka.
English: Pulse oximetry may be useful but is not essential for adequate monitoring.
Croatian: Pulsna oksimetrija može biti korisna, ali nije neophodna za adekvatan nadzor.
English: EXP {month/year} Once broached use by
Croatian: EXP{mjesec/godina} Jednom otvoren, upotrijebiti do:
English: *only intramuscularly
Croatian: * samo intramuskularno
English: The eyes should be protected by a suitable eye lubricant.
Croatian: Oči treba zaštititi prikladnim lubrikantom za oči.
English: Do not use in animals with severe systemic disease or in animals that are moribund.
Croatian: Ne primjenjivati na životinjama s teškim sustavnim bolestima ili na životinjama koje su na umoru.
English: The mean half-life of elimination of dexmedetomidine increased to 1.6 h and the total exposure (AUC) increased by 50%.
Croatian: Prosječno poluvrijeme eliminacije deksmedetomidina povećalo se na 1,6 h, a ukupna izloženost (AUC) povećala se za 50%.
English: All known metabolites lack pharmacological activity.
Croatian: Svi su poznati metaboliti bez farmakološke aktivnosti.
English: Frequent and regular monitoring of respiratory and cardiac function should be performed.
Croatian: Potrebno je često i redovito pratiti respiratornu i kardijalnu funkciju.
English: Within 15 minutes dogs and cats are normally awake and standing.
Croatian: Kroz 15 minuta psi i mačke su normalnog stanja budnosti te ustaju.
English: The maximum plasma concentration is reached about 0.24 h after intramuscular administration.
Croatian: Maksimalna koncentracija u plazmi postiže se oko 0,24 h nakon intramuskularne primjene.
English: Treated animals should be kept warm and at a constant temperature, both during the procedure and recovery.
Croatian: Tretirane životinje treba držati na toplom i na stalnoj temperaturi, kako za vrijeme postupka, tako i tijekom oporavka.
English: It is also advisable to have oxygen readily available, should hypoxaemia be detected or suspected.
Croatian: Također je uputno imati odmah dostupan kisik u slučaju detektiranja hipoksemije ili da se na nju posumnja.
English: In the circulation, dexmedetomidine is largely bound to plasma proteins (>90%).
Croatian: U cirkulaciji je veliki dio deksmedetomidina vezan za proteine plazme (>90%).
English: Avoid skin, eye or mucosal contact; the use of impermeable gloves is advisable.
Croatian: Izbjegavati kontakt s kožom, očima ili sluznicom; preporučuje se upotreba nepropusnih rukavica.
English: Not all pack sizes may be marketed.
Croatian: U prometu možda neće biti sve veličine pakovanja.
English: Ventricular arrhythmias have also been reported.
Croatian: Ventrikularne aritmije su također zabilježene.
English: Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes.
Croatian: Preporučuje se upotreba prikladno baždarene štrcaljke kako bi se osiguralo točno doziranje kod primjene malih volumena.
English: However this duration is dependent on a number of variables and further analgesia should be administered in accordance with clinical judgement.
Croatian: Ipak, ovo je trajanje ovisno o nizu parametara pa bi primjenu daljnje analgezije trebalo provoditi u skladu s kliničkom prosudbom.
English: The dose should be adjusted to the type of surgery, length of procedure and patient temperament.
Croatian: Dozu treba prilagoditi ovisno o vrsti operacije, trajanju postupka i temperamentu pacijenta.
English: According to studies in rats, the maximum concentration in the central nervous system is several times that of the corresponding concentration in plasma.
Croatian: Prema ispitivanjima na štakorima, maksimalna koncentracija u središnjem živčanom sustavu nekoliko je puta veća od koncentracije u plazmi.
English: For deep sedation and analgesia with butorphanol
Croatian: Za duboku sedaciju i analgeziju s butorfanolom
English: The veterinary medicinal product is not intended for repeat injections.
Croatian: Ovaj veterinarsko-medicinski proizvod nije namijenjen za ponavljano injiciranje.