FrancophonIA/ELRC3.0 huggingface dataset:
English: Main human metabolites are N-3,5-dimethyl-gludantan, the isomeric mixture of 4- and 6-hydroxy-memantine, and 1-nitroso-3,5-dimethyl-adamantane.
Danish: Humane hovedmetabolitter er N-3,5-dimethyl-gludantan, den isomeriske blanding af 4- og 6-hydroxy-memantin og 1-nitroso-3,5-dimethyl-adamantan.
English: Memantine Merz belongs to a group of medicines called NMDA-receptor antagonists.
Danish: Memantine Merz hører til en gruppe af medicin kaldet NMDA-receptor-antagonister.
English: Place the bottle on a flat, horizontal surface, for example a table top, and only use it in a upright position.
Danish: Sæt flasken på en flad, vandret overflade, f.eks. på en bordplade, og brug kun pumpen, når den er opretstående.
English: week 2
Danish: 2. uge
English: If you go into hospital, let your doctor know that you are taking Memantine Merz.
Danish: Hvis De kommer på hospitalet, skal De sige til lægen, at De får Memantine Merz.
English: In clinical trials in mild to severe dementia, involving 1,784 patients treated with Memantine Merz and 1,595 patients treated with placebo, the overall incidence rate of adverse reactions with Memantine Merz did not differ from those with placebo; the adverse reactions were usually mild to moderate in severity.
Danish: I kliniske forsøg med 1.784 patienter i behandling med Memantine Merz for mild til svær demens og med 1.595 patienter i placebobehandling adskilte den generelle incidensrate for biverkninger med Memantine Merz sig ikke fra placebobehandlingen, og bivirkningerne var som regel milde til moderate.
English: Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Danish: Fortæl det altid til lægen eller apoteket, hvis De bruger anden medicin eller har brugt det for nylig.
English: Memantine Merz contains the active substance memantine hydrochloride.
Danish: Memantine Merz indeholder det aktive stof memantinhydrochlorid.
English: In another monotherapy study in mild to moderate Alzheimer's disease a total of 470 patients (MMSE total scores at baseline of 11-23) were randomised.
Danish: I en anden monoterapiundersøgelse med mild til moderat Alzheimers sygdom blev i alt 470 patienter randomiseret (samlet MMSE-score ved baseline 11-23).
English: When daily doses of 5 to 30 mg were administered, a mean cerebrospinal fluid (CSF)/serum ratio of 0.52 was calculated.
Danish: Ved indgivelse af daglige doser på 5 til 30 mg udregnedes en gennemsnitlig cerebrospinalvæske (CSF)/serumværdi på 0,52.
English: No data on the use of memantine in patients with severe hepatic impairment are available.
Danish: Der foreligger ikke tilgængelige data om brug af memantin hos patienter med svært nedsat leverfunktion.
English: Furthermore, Memantine Merz has minor to moderate influence on the ability to drive and use machines such that outpatients should be warned to take special care.
Danish: Derudover har Memantine Merz mindre til moderat indflydelse på evnen til at føre motorkøretøj og betjene maskiner, hvorfor ambulante patienter skal informeres om at være særligt forsigtige.
English: 7 film-coated tablets.
Danish: 7 filmovertrukne tabletter.
English: The solution also contains potassium sorbate and sorbitol (E 420).
Danish: Opløsningen indeholder også kaliumsorbat og sorbitol (E 420).
English: Blister packs containing 14 film-coated tablets per PVDC/PE/PVC/Al-blister or PP/Al-blister strip.
Danish: 6.5 Emballagetype og pakningsstørrelser Blisterpakninger indeholder 14 filmovertrukne tabletter pr. PVDC/PE/PVC/Alu-blisterstrip eller PP/Alu-blisterstrip.
English: Therefore, the pump must be prepared (primed) by pushing the dosing pump head down completely five times in succession (fig. 5).
Danish: Derfor skal pumpen klargøres (fyldes op) ved at trykke doseringspumpen helt ned fem gange i træk (fig. 5).
English: Each pack of 28 film-coated tablets for a 4 week treatment schedule contains: 7 x Memantine Merz 5 mg
Danish: Hver pakke med 28 filmovertrukne tabletter til et 4-ugers behandlingsforløb indeholder: 7 x Memantine Merz 5 mg
English: The dosing pump head can then be released and is ready for the next pump actuation.
Danish: Doseringspumpen slippes og er nu klar til næste tryk på pumpen.
English: Mounting the dosing pump on the bottle:
Danish: Påsætning af doseringspumpen på flasken:
English: Correct use of the dosing pump:
Danish: Korrekt brug af doseringspumpen:
English: week 3
Danish: 3. uge
English: In the overdose cases below 140 mg or unknown dose the patients revealed symptoms from central nervous system (confusion, drowsiness, somnolence, vertigo, agitation, aggression, hallucination and gait disturbance) and/or gastrointestinal origin (vomiting and diarrhoea).
Danish: I tilfælde af overdosering med doser under 140 mg eller ukendt dosis har patienterne haft symptomer fra centralnervesystemet (forvirring, døsighed, sløvhed (søvntrang), svimmelhed, agitation, aggression, hallucinationer og gangforstyrrelser) og/eller fra mave-tarmkanalen (opkastning og diarré).
English: In order to reduce the risk of side effects this dose is achieved gradually by the following daily treatment scheme.
Danish: For at mindske risikoen for bivirkninger opnås denne dosis gradvist ud fra følgende daglige behandlingsskema.
English: Memantine is a voltage-dependent, moderate-affinity uncompetitive NMDA-receptor antagonist.
Danish: Memantin er en ikke-kompetitiv, spændingsafhængig NMDA-receptorantagonist med moderat affinitet.
English: The other ingredients are: potassium sorbate, sorbitol (E 420) and purified water.
Danish: Øvrige indholdsstoffer: Kaliumsorbat, sorbitol (E 420) og renset vand.
English: Talk to your doctor or pharmacist before taking Memantine Merz - if you have a history of epileptic seizures - if you have recently experienced a myocardial infarction (heart attack), or if you are suffering from congestive heart failure or from an uncontrolled hypertension (high blood pressure).
Danish: Kontakt lægen eller apoteketspersonalet, før De tager Memantine Merz - hvis De tidligere har haft epileptiske anfald - hvis De for nylig har haft en blodprop i hjertet (myokardieinfarkt) , eller hvis De lider af dårligt hjerte eller ukontrolleret forhøjet blodtryk (hypertension).
English: Standard clinical procedures to remove active substance material, e.g. gastric lavage, carbo medicinalis (interruption of potential entero-hepatic recirculation), acidification of urine, forced diuresis should be used as appropriate.
Danish: Der bør anvendes passende standardprocedurer for at fjerne det aktive stof, f.eks. ventrikeltømning, medicinsk kul (afbrydelse af potentiel enterohepatisk recirkulation), surgøring af urinen og forceret diurese.
English: Women taking Memantine Merz should not breast-feed.
Danish: Kvinder, der tager Memantine Merz, bør ikke amme.
English: What you need to know before you take Memantine Merz Do not take Memantine Merz
Danish: Det skal de vide, før de begynder at tage Memantine Merz Tag ikke Memantine Merz
English: The following Adverse Reactions listed in the Table below have been accumulated in clinical studies with Memantine Merz and since its introduction in the market.
Danish: Følgende bivirkninger i nedenstående tabel er indrapporteret i forbindelse med kliniske forsøg med Memantine Merz og efter markedsføring.
English: From the fourth week on, the usual dose is 2 tablets once a day (1x 20 mg).
Danish: Fra og med den fjerde uge er den normale dosis 2 tabletter en gang om dagen (1 x 20 mg).
English: Each tablet contains 5/10/15/20 mg of memantine hydrochloride equivalent to 4.15/8.31/12.46/16.62 mg memantine.
Danish: Hver tablet indeholder 5/10/15/20 mg memantinhydrochlorid (svarende til 4,15/8,31/12,46/16,62mg memantin).
English: In order to reduce the risk of side effects this dose is achieved gradually by the following daily treatment scheme:
Danish: For at mindske risikoen for bivirkninger opnås denne dosis gradvist ud fra følgende daglige behandlingsskema:
English: In patients with mildly impaired renal function (creatinine clearance 50 - 80 ml/min) no dose adjustment is required.
Danish: Hos patienter med let nedsat nyrefunktion (kreatinin-clearance 50-80 ml/min) er dosisjustering ikke påkrævet.
English: Ocular changes were inconsistently observed in repeat dose toxicity studies in rodents and dogs, but not in monkeys.
Danish: I toksicitetsstudier med gentagen dosis var der modstridende observationer af okulære forandringer hos gnavere og hunde, men ikke hos aber.
English: Additional for 15 mg and 20 mg film-coated tablets: Iron oxide yellow and red (E 172)
Danish: Yderligere for 15 og 20 mg filmovertrukne tabletter: Gul og rød jernoxid (E 172)
English: See package leaflet for further information.
Danish: Pakningsstørrelser og y derligere oplysninger
English: Do not use Memantine Merz after the expiry date which is stated on the carton and the bottle label after the EXP.
Danish: Brug ikke Memantine Merz efter den udløbsdato, der står på æsken og flaskeetiketten efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: To unlock, turn the pump head in the direction of the arrow until it cannot be turned any further (about one eighth of a turn, fig. 4).
Danish: For at åbne pumpen skal De dreje pumpens top i pilens retning, indtil De ikke kan dreje den længere (ca. 1/8 omgang, fig. 4).
English: Venous thrombosis/thromboembolism
Danish: Venetrombose/ tromboembolisme (blodpropper)
English: CARTON AND LABEL FOR 50 ml BOTTLE AS INTERMEDIATE PACK / COMPONENT OF A MULTIPACK (WITHOUT BLUE BOX)
Danish: ÆSKE OG MÆRKAT TIL 50 ml FLASKE SOM INTERMEDIÆR PAKNING / KOMPONENTERNE AF MULTIPAKNINGEN (EKSKLUSIV »BLUE BOX«)
English: The use of medicinal products called amantadine (for the treatment of Parkinson´s disease), ketamine (a substance generally used as an anaesthetic), dextromethorphan (generally used to treat cough) and other NMDA-antagonists at the same time should be avoided.
Danish: Samtidig brug af medicin ved navn amantadin (til behandling af Parkinsons sygdom), ketamin (et middel, der anvendes til bedøvelse), dextromethorfan (anvendes generelt til behandling af hoste) og andre NMDA-antagonister bør undgås.
English: Multipack 840 (20 packs of 42) film-coated tablets Multipack 980 (10 packs of 98) film-coated tablets Multipack 1000 (20 packs of 50) film-coated tablets
Danish: Multipakning 840 (20 pakninger a 42) filmovertrukne tabletter Multipakning 980 (10 pakninger a 98) filmovertrukne tabletter Multipakning 1000 (20 pakninger a 50) filmovertrukne tabletter
English: You should inform your doctor if you have recently changed or intend to change your diet substantially (e.g. from normal diet to strict vegetarian diet) or if you are suffering from states of renal tubulary acidosis (RTA, an excess of acid-forming substances in the blood due to renal dysfunction (poor kidney function)) or severe infections of the urinary tract (structure that carries urine), as your doctor may need to adjust the dose of your medicine.
Danish: De bør informere Deres læge, hvis De for nylig har ændret eller har i sinde at ændre Deres kost væsentligt (f.eks. fra en normal kost til en streng vegetarisk kost), eller hvis De lider at tilstande med renal tubulær acidose (RTA, overskud af syredannende stoffer i blodet på grund af nedsat nyrefunktion) eller alvorlige infektioner i urinvejene (som urinen udskilles igennem), da Deres læge i så fald kan være nødt til at justere dosis af Deres medicin.
English: Preparing the dosing pump:
Danish: Forberedelse af doseringspumpen:
English: Common (may affect up to 1 in 10 users):
Danish: Almindelige (kan påvirke op til 1 ud af 10 brugere):
English: A pivotal monotherapy study in a population of patients suffering from moderate to severe Alzheimer's disease (mini mental state examination (MMSE) total scores at baseline of 3 - 14) included a total of 252 outpatients.
Danish: I en pivotal monoterapiundersøgelse med en patientpopulation, der led af moderat til svær Alzheimers sygdom (med en samlet Mini mental state examination (MMSE)-score ved baseline på 3-14), indgik i alt 252 ambulante patienter.
English: Patients with rare hereditary problems of fructose intolerance should not take this medicine.
Danish: Bør ikke anvendes til patienter med arvelig fructoseintolerans.
English: Maintenance dose The recommended maintenance dose is 20 mg per day.
Danish: Vedligeholdelsesdosis Den anbefalede vedligeholdelsesdosis er 20 mg pr. dag.
English: The recommended maintenance dose is 20 mg (2 ml solution, equivalent to four pump actuations) per day.
Danish: Den anbefalede vedligeholdelsesdosis er 20 mg (2 ml opløsning, hvilket svarer til fire tryk på pumpen) dagligt.
English: Do not use Memantine Merz after the expiry date which is stated on the carton and the blister after EXP.
Danish: Brug ikke Memantine Merz efter den udløbsdato, der står på æsken og blisteret efter EXP. Udløbsdatoen er den sidste dag i den nævnte måned.
English: EU/1/12/799/025 28 film-coated tablets EU/1/12/799/026 28 film-coated tablets
Danish: EU/1/12/799/025 28 filmovertrukne tabletter EU/1/12/799/026 28 filmovertrukne tabletter
English: If you forget to take Memantine Merz
Danish: Hvis De har glemt at tage Memantine Merz
English: This dose is increased in the second week to two pump actuations once daily (1 x 10 mg), and in the third week to three pump actuations (1 x 15 mg) once daily.
Danish: Denne dosis øges til 2 tryk på pumpen en gang dagligt (1 x 10 mg) i den anden uge og til 3 tryk på pumpen (1 x 15 mg) en gang dagligt i den tredje uge.
English: The usual starting dose is half a tablet once a day (1x 5 mg) for the first week.
Danish: Den normale startdosis er en halv tablet en gang om dagen (1 x 5 mg) i den første uge.
English: The next time the dosing pump head is pushed downwards completely (equivalent to one pump actuation), it dispenses the correct dose (fig. 6).
Danish: Næste gang De trykker doseringspumpen helt ned (dvs. når der trykkes én gang på pumpen), bliver den korrekte dosis pumpet ud (fig. 6).
English: Check with your doctor or pharmacist if you are not sure.
Danish: Spørg lægen eller på apotekspersonalet, hvis der er noget, De er i tvivl om.
English: Additional for 10 mg film-coated tablets: Iron oxide yellow (E 172)
Danish: Yderligere for 10 mg filmovertrukne tabletter: Gul jernoxid (E 172)
English: The recommended dose of Memantine Merz for adults and elderly patients is 20 mg once a day.
Danish: Den anbefalede dosis af Memantine Merz til voksne og til ældre patienter er 20 mg en gang om dagen.
English: Do not store above 30ºC.
Danish: Må ikke opbevares over 30oC.
English: The active substance is memantine hydrochloride.
Danish: Aktivt stof: Memantinhydrochlorid.
English: In postmarketing experience these events have been reported in patients treated with Memantine Merz.
Danish: Efter markedsføringen er disse hændelser rapporteret hos patienter i behandling med Memantine Merz.
English: 14 film-coated tablets 28 film-coated tablets 42 film-coated tablets 56 film-coated tablets 98 film-coated tablets
Danish: 14 filmovertrukne tabletter 28 filmovertrukne tabletter 42 filmovertrukne tabletter 56 filmovertrukne tabletter 98 filmovertrukne tabletter
English: The dosing pump has to be removed from the plastic bag (fig. 2) and placed on top of the bottle, sliding the plastic dip tube carefully into the bottle.
Danish: Doseringspumpen tages ud af plastikposen (fig. 2) og sættes på flaskehalsen ved forsigtigt at stikke plastikslangen ned i flasken.
English: • Tiredness, fungal infections, confusion, hallucinations, vomiting, abnormal gait, heart failure and venous blood clotting (thrombosis/thromboembolism)
Danish: • Træthed, svampeinfektioner, forvirring, hallucinationer, opkastning, unormal gang, hjertesvigt og blodprop i en blodåre (vene)
English: How the dosing pump works:
Danish: Hvordan virker doseringspumpen:
English: The dosing pump head has two positions and is easy to turn: anticlockwise to unlock and clockwise to lock.
Danish: Doseringspumpen har to indstillingsmuligheder og er nem at dreje: - mod uret for at åbne pumpen og - med uret for lukke pumpen.
English: To do this, the dosing pump head has to be turned in the direction of the arrow about one eighth of a turn, until a resistance is felt (fig. 4).
Danish: For at åbne doseringspumpen skal toppen af pumpen drejes i pilens retning ca. 1/8 omgang, indtil der mærkes modstand (fig. 4).
English: A pivotal monotherapy study of memantine in the treatment of mild to moderate Alzheimer's disease (MMSE total scores at baseline of 10 to 22) included 403 patients.
Danish: I en pivotal monoterapiundersøgelse med memantin til behandling af mild til moderat Alzheimers sygdom (med en samlet MMSE-score ved baseline på 10-22) indgik 403 patienter.
English: Concomitant use of other N-methyl-D-aspartate (NMDA)-antagonists such as amantadine, ketamine or dextromethorphan should be avoided.
Danish: Samtidig brug af andre N-metyl-D-aspartat(NMDA)-antagonister såsom amantadin, ketamin eller dextromethorfan bør undgås.
English: 14 film-coated tablets 28 film-coated tablets 30 film-coated tablets 42 film-coated tablets 50 film-coated tablets 56 film-coated tablets 98 film-coated tablets 100 film-coated tablets 112 film-coated tablets
Danish: 28 filmovertrukne tabletter 30 filmovertrukne tabletter 42 filmovertrukne tabletter 50 filmovertrukne tabletter 56 filmovertrukne tabletter 98 filmovertrukne tabletter 100 filmovertrukne tabletter 112 filmovertrukne tabletter
English: Concomitant use of N-methyl-D-aspartate(NMDA)-antagonists such as amantadine, ketamine or dextromethorphan should be avoided.
Danish: Samtidig brug af N-metyl-D-aspartat(NMDA)-antagonister såsom amantadin, ketamin eller dextromethorfan bør undgås.
English: Your doctor should assess your treatment on a regular basis.
Danish: I så fald bør Deres læge overvåge Deres nyrefunktion regelmæssigt.
English: The other ingredients for Memantine Merz 5/10/15 and 20 mg film-coated tablets are microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate, all in the tablet core; and hypromellose, macrogol 400, titanium dioxide (E 171) and additional for Memantine Merz 10 mg film-coated tablets is iron oxide yellow (E172) and for Memantine Merz 15 mg and Memantine Merz 20 mg film-coated tablets are iron oxide yellow and red (E 172), all in the tablet coating.
Danish: Øvrige indholdsstoffer for Memantine Merz 5/10/15 og 20 mg filmovertrukne tabletter er mikrokrystallinsk cellulose, croscarmellosenatrium, kolloid vandfri silica, magnesiumstearat, som alle findes i tablettens kerne, og hypromellose, macrogol 400, titandioxid (E 171) og desuden for Memantine Merz 10 mg filmovertrukne tabletter er gul jernoxid (E 172) og for Memantine Merz 15 mg og Memantine Merz 20 mg filmovertrukne tabletter også gul og rød jernoxid (E 172), som alle findes i tablettens overtræk.
English: 20 mg tablets once a day
Danish: En tablet à 20 mg én gang dagligt
English: The solution can be taken with or without food.
Danish: Opløsningen kan indtages uafhængigt af måltider.
English: Also, Memantine Merz may change your reactivity, making driving or operating machinery inappropriate.
Danish: Desuden kan Memantine Merz påvirke Deres reaktionsevne, så det ikke er hensigtsmæssigt at køre bil eller betjene maskiner.
English: Pack sizes of 14, 28, 30, 42, 50, 56, 98, 100, 112, and multipacks containing 840 (20 x 42), 980 (10 x 98) or 1000 (20 x 50) tablets are presented.
Danish: Fås i pakningsstørrelser på 14, 28, 30, 42, 50, 56, 98, 100, 112 og multipakninger med 840 (20 x 42), 980 (10 x 98) eller 1.000 (20 x 50) tabletter.
English: In order to reduce the risk of undesirable effects the maintenance dose is achieved by upward titration of 5 mg per week over the first 3 weeks as follows.
Danish: For at reducere risikoen for bivirkninger opnås vedligeholdelsesdosis ved en gradvis dosisøgning på 5 mg om ugen i de første 3 uger som følger.
English: 50 film-coated tablets
Danish: 50 filmovertrukne tabletter
English: Administration of Memantine Merz in patients with severe hepatic impairment is not recommended.
Danish: Administration af Memantine Merz til patienter med svært nedsat leverfunktion kan ikke anbefales.
English: The usual starting dose is one pump actuation (1 x 5 mg) once daily for the first week.
Danish: Den sædvanlige startdosis er 1 tryk på pumpen (1 x 5 mg) en gang dagligt i den første uge.
English: shortness of breath, high blood pressure and drug hypersensitivity
Danish: svimmelhed, balanceforstyrrelser kortåndethed, forhøjet blodtryk og overfølsomhed over for medicinen
English: Uncommon (may affect up to 1 in 100 users):
Danish: Ikke almindelige (kan påvirke op til 1 ud af 100 brugere):
English: Tablet coating for 5/10/15/20 mg film-coated tablets Hypromellose
Danish: Tabletovertræk for 5/10/15/20 mg filmovertrukne tabletter
English: These events have been reported in patients treated with Memantine Merz.
Danish: Disse følger er blevet set hos patienter i behandling med Memantine Merz.
English: For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder.
Danish: Hvis De ønsker yderligere oplysninger om Memantine Merz, skal De henvende Dem til den lokale repræsentant for indehaveren af markedsføringstilladelsen:
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING INNER CARTON FOR BLISTER PACK; front and backside
Danish: MÆRKNING, DER SKAL ANFØRES PÅ DEN YDRE EMBALLAGE INDRE ÆSKE TIL BLISTERPAKNING; for- og bagside
English: Titanium dioxide (E 171) Iron oxide yellow and red (E 172)
Danish: Titandioxid (E 171) Gul og rød jernoxid (E 172)
English: Memantine Merz film-coated tablets are available in blister packs of 14 tablets, 28 tablets, 42 tablets, 56 tablets, 98 tablets or in multipacks of 840 (20 x 42) tablets.
Danish: Memantine Merz filmovertrukne tabletter fås i blisterpakninger med 14 tabletter, 28 tabletter, 42 tabletter, 56 tabletter eller 98 tabletter og multipakninger med 840 (20 x 42) tabletter.
English: EU/1/12/799/018 840 film-coated tablets (20 packs of 42) EU/1/12/799/024 840 film-coated tablets (20 packs of 42)
Danish: EU/1/12/799/018 840 filmovertrukne tabletter (20 x 42) EU/1/12/799/024 840 filmovertrukne tabletter (20 x 42)
English: In order to reduce the risk of undesirable effects the maintenance dose is achieved by upward titration of 5 mg per week over the first 3 weeks as follows:
Danish: For at reducere risikoen for bivirkninger opnås vedligeholdelsesdosis ved en gradvis dosisøgning på 5 mg om ugen i de første 3 uger som følger:
English: The maximum daily dose is 20 mg per day.
Danish: Den maksimale daglige dosis er 20 mg pr. dag.
English: No adverse effects of memantine were noted on non-clinical male and female fertility studies.
Danish: Der er ikke registreret uønskede virkninger af memantin i forbindelse med ikke-kliniske fertilitetsstudier hos hanner og hunner.
English: Fungal infections
Danish: Svampeinfektioner
English: Take the screw cap off the bottle: The cap must be turned anticlockwise, unscrewed completely and removed (fig. 1).
Danish: Tag skruelåget af flasken: Låget skal drejes i retning mod uret, skru låget helt af og fjern det (fig. 1).
English: Memantine Merz 5 mg, 10 mg, 15 mg, 20 mg tablets
Danish: Memantine Merz 5 mg, 10 mg, 15 mg, 20 mg tabletter
English: Memantine Merz belongs to a group of medicines known as anti-dementia medicines.
Danish: Memantine Merz tilhører gruppen af medicin kaldet antidemensmedicin (medicin til behandling af demens).
English: The recommended starting dose is 5 mg per day which is stepwise increased over the first 4 weeks of treatment reaching the recommended maintenance dose as follows:
Danish: Den anbefalede startdosis er 5 mg pr. dag med gradvis dosisøgning over de første fire uger som følger:
English: At a dose of memantine of 20 mg per day the CSF levels match the ki-value (ki = inhibition constant) of memantine, which is 0.5 µmol in human frontal cortex.
Danish: Ved en dosis af memantin på 20 mg pr. dag svarer CSF-niveauerne til ki-værdien (ki = hæmningsfaktor) for memantin, som er 0,5 µmol i den humane frontale cortex.
English: Immune systeme disorders
Danish: Immunsystemet
English: one pump actuation.
Danish: 1 tryk på pumpen