FrancophonIA/ELRC3.0 huggingface dataset:
English: In populations where the dose may be increased to 8 mg once daily, the dose increase should be preceded by an evaluation of the individual response and tolerability.
Danish: I populationer, hvor dosis kan øges til 8 mg 1 gang dagligt, skal øgningen af dosis ledsages af en evaluering af den enkeltes respons og tolerance.
English: Number of urge incontinence episodes per 24 hours
Danish: Antal episoder med urgeinkontinens pr. 24 timer
English: For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:
Danish: Hvis du ønsker yderligere oplysninger om denne medicin, skal du henvende dig til den lokale repræsentant for indehaveren af markedsføringstilladelsen:
English: Fesoterodine has been safely administered in clinical studies at doses up to 28 mg/day.
Danish: Fesoterodin er i kliniske undersøgelser administreret sikkert ved doser på op til 28 mg/dag.
English: TOVIAZ has minor influence on the ability to drive and use machines.
Danish: TOVIAZ påvirker i mindre grad evnen til at føre motorkøretøj eller betjene maskiner.
English: The maximum daily dose is 8 mg.
Danish: Den maksimale daglige dosis er 8 mg.
English: Table 1: Mean changes from Baseline to end of treatment for primary and selected secondary endpoints Study 1
Danish: Tabel 1: Gennemsnitlig ændring fra baseline til behandlingsafslutning for primære og udvalgte sekundære endepunkter.
English: You should stop taking TOVIAZ and contact your doctor immediately if you develop swelling of the face, mouth or throat.
Danish: Du skal stoppe med at tage TOVIAZ, og straks kontakte lægen, hvis du får hævelser i ansigtet, munden eller svælget.
English: Show them your pack of tablets.
Danish: Vis dem æsken med tabletterne.
English: Therapeutic plasma levels are achieved after the first administration of fesoterodine.
Danish: Det terapeutiske plasmaniveau opnås efter første administration af fesoterodin.
English: Hepatic metabolism and renal excretion contribute significantly to the elimination of the active metabolite.
Danish: Hepatisk metabolisering og renal udskillelse bidrager væsentligt til eliminationen af den aktive metabolit.
English: No clinical trials have been conducted to assess the effect of fesoterodine on human fertility.
Danish: Der er ikke udført kliniske forsøg med henblik på vurdering af fesoterodins virkning på fertilitet hos mennesker.
English: If you have taken more tablets than you have been told to take, or if someone else accidentally takes your tablets, contact your doctor or hospital for advice immediately.
Danish: Hvis du har taget flere tabletter, end lægen har foreskrevet, eller hvis en anden ved et uheld indtager dine tabletter, skal du omgående kontakte lægen eller hospitalet og spørge om råd.
English: Change from baseline in QTc based on the Fridericia correction method did not show any differences between the active treatment and placebo group.
Danish: Ændring i QTc fra baseline baseret på Fridericia korrektionsmetoden viste ingen forskelle mellem den aktive behandling og placebogruppen.
English: - medicines containing the active substance methadone (used in the treatment of severe pain and abuse problems).
Danish: - Medicin, der indeholder det aktive stof methadon (bruges til at behandle stærke smerter og misbrugsproblemer).
English: Clinical efficacy and safety
Danish: Klinisk vurdering og sikkerhed
English: Do not chew the tablet.
Danish: Du må ikke tygge tabletten.
English: R-Pharm Germany GmbH Heinrich-Mack-Str. 35, 89257 Illertissen Germany
Danish: R-Pharm Germany GmbH Heinrich-Mack-Str. 35, 89257 Illertissen Tyskland
English: Overdose with antimuscarinics, including fesoterodine can result in severe anticholinergic effects.
Danish: Overdosering med antimuskarine stoffer, herunder fesoterodin, kan resultere i svære antikolinerge virkninger.
English: Thus fesoterodine is unlikely to alter the clearance of medicinal products that are metabolised by these enzymes.
Danish: Det er derfor ikke sandsynligt, at fesoterodin ændrer clearance af lægemidler, som metaboliseres af disse enzymer.
English: None of these metabolites contribute significantly to the antimuscarinic activity of fesoterodine.
Danish: Ingen af disse metabolitter bidrager væsentligt til fesoterodins antimuskarine aktivitet.
English: Plasma protein binding of the active metabolite is low with approximately 50% bound to albumin and alpha-1-acid glycoprotein.
Danish: Den aktive metabolits plasma-proteinbinding er lav med cirka 50% bundet til albumin og alpha-1syre-glycoprotein.
English: The interaction with CYP2D6 inhibitors was not tested clinically.
Danish: Interaktion med CYP2D6-hæmmere er ikke klinisk undersøgt.
English: It is rapidly and extensively hydrolysed by non-specific plasma esterases to the 5-hydroxymethyl derivative, its primary active metabolite, which is the main active pharmacological principle of fesoterodine.
Danish: Den hydrolyseres hurtigt og omfattende via ikke-specifikke plasmaesteraser til et 5-hydroxymethylderivat, den primære aktive metabolit, som er fesoterodins primære, aktive farmakologiske princip.
English: The maternal No-Observed-Effect Level (NOEL) and the NOEL for effects on reproduction and early embryonic development were both 15 mg/kg/day.
Danish: Niveauet for Ingen Observeret Effekt (NOEL) hos moderdyr og NOEL for effekt på reproduktion og tidlig embryonal udvikling er 15 mg/kg/dag.
English: Other causes of frequent urination (treatment of heart failure or renal disease) should be assessed before treatment with fesoterodine.
Danish: Andre årsager til hyppig vandladning (behandling af hjertesvigt eller nyresygdom) bør vurderes, før der behandles med fesoterodin.
English: The terminal half-life of the active metabolite following oral administration is approximately 7 hours and is absorption rate-limited.
Danish: Den terminale halveringstid af den aktive metabolit efter oral administration er cirka 7 timer og er betinget af absorptionshastighed.
English: If you experience any of these effects, do not drive or use any tools or machines.
Danish: Hvis du får nogen af disse bivirkninger, må du ikke køre bil, motorcykel eller cykel eller arbejde med værktøj eller maskiner.
English: In non-clinical safety pharmacology, general toxicity, genotoxicity and carcinogenicity studies no clinically relevant effects have been observed, except those related to the pharmacological effect of the active substance.
Danish: I ikke-klinisk sikkerhedsfarmakologiske, generel toksicitets-, genotoksicitets- samt karcinogenecitetsforsøg sås ingen klinisk relevant virkning, med undtagelse af virkningen, som var forbundet med lægemidlets farmakologiske virkning.
English: After oral administration, fesoterodine is rapidly and extensively hydrolysed to its active metabolite.
Danish: Efter oral administration bliver fesoterodin hurtigt og omfattende hydrolyseret til den aktive metabolit.
English: Dry mouth, the only very common adverse reactions, occurred with a frequency of 28.8% in the fesoterodine group compared to 8.5% in the placebo group.
Danish: Mundtørhed, som er den eneste meget almindelige bivirkning, forekom med en frekvens på 28,8% i fesoterodin-gruppen sammenlignet med 8,5% i placebogruppen.
English: The majority of adverse reactions occurred during the first month of treatment with the exception of cases classified as urinary retention or post void residual urine greater than 200 ml, which could occur after long term treatment and was more common in male than female subjects.
Danish: Hovedparten af bivirkningerne forekom i løbet af den første måned af behandlingen, med undtagelse af urinretention med mere end 200 ml residualurin, der kunne forekomme efter længere tids behandling og forekom hyppigere hos mænd end hos kvinder.
English: TOVIAZ contains an active substance called fesoterodine fumarate, and is a so called antimuscarinic treatment which reduces the activity of an overactive bladder and it is used in adults to treat the symptoms.
Danish: TOVIAZ indeholder et aktivt stof, som kaldes fesoterodinfumarat, og det er en såkaldt antimuskarin behandling, der nedsætter aktiviteten af en overaktiv blære og det anvendes til at behandle symptomerne hos voksne.
English: Reproductive toxicity studies with fesoterodine in animals show minor embryotoxicity.
Danish: Reproduktive toksicitetesforsøg med fesoterodin i dyr viser lettere embroyotoksicitet.
English: The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Danish: Indehaveren af markedsføringstilladelsen skal udføre de påkrævede lægemiddelovervågningsaktiviteter og foranstaltninger vedrørende lægemiddelovervågning, som er beskrevet i den godkendte RMP version i modul 1.8.2 i markedsføringstilladelsen, og enhver efterfølgende godkendt opdatering af RMP.
English: The safety of fesoterodine was evaluated in placebo-controlled clinical studies in a total of 2859 patients with overactive bladder, of which 780 received placebo.
Danish: Sikkerheden af fesoterodin blev vurderet i placebokontrollerede kliniske forsøg med i alt 2.859 patienter med overaktiv blære, hvoraf 780 fik placebo.
English: Post-marketing cases of urinary retention requiring catheterisation have been described, generally within the first week of treatment with fesoterodine.
Danish: Efter markedsføring, er der set tilfælde af urinretention, hvor kateterindføring har været nødvendig, normalt inden for den første uge af behandlingen med fesoterodin.
English: If urinary tract infection is present, an appropriate medical approach should be taken/antibacterial therapy should be started.
Danish: Hvis der er urinvejsinfektion, bør relevant medicinsk/antibakteriel behandling indledes.
English: Induction of CYP3A4 may lead to subtherapeutic plasma levels.
Danish: Induktion af CYP3A4 kan føre til subterapeutiske plasmaniveauer.
English: In a study of fertility and early embryonic development in mice, fesoterodine had no effect on male reproductive function or fertility at doses up to 45 mg/kg/day.
Danish: I et forsøg vedrørende fertilitet og tidlig embryonal udvikling hos mus havde fesoterodin ingen virkning på den reproduktive funktion eller fertilitet hos hanner ved doser på op til 45 mg/kg/dag.
English: Reproduction studies have shown minor embryotoxicity at doses close to maternally toxic ones (increased number of resorptions, pre-implantation and post-implantation losses).
Danish: Reproduktionsforsøg har vist mindre embryotoksicitet ved doser, som var toksiske for moderen (øget antal resorptioner samt præimplantatorisk og postimplantatorisk embryotab).
English: • Severe hepatic impairment (Child Pugh C)
Danish: • Svært nedsat leverfunktion (Child Pugh C)
English: The incidence rates of QTc 500 ms post baseline or QTc increase of 60 ms is 1.9%, 1.3%, 1.4% and 1.5%, for fesoterodine 4 mg, 8 mg, 12 mg and placebo, respectively.
Danish: Incidensen af QTc ≥ 500 ms post baseline eller af QTc-stigning på ≥ 60 ms er henholdsvis 1,9%, 1,3%, 1,4% og 1,5%, for fesoterodin 4 mg, 8 mg, 12 mg og placebo.
English: Do not store above 25oC.
Danish: Må ikke opbevares ved temperaturer over 25°C.
English: Based upon individual response, the dose may be increased to 8 mg once daily.
Danish: På basis af individuelt respons kan dosis øges til 8 mg 1 gang dagligt.
English: In vitro data demonstrate that the active metabolite of fesoterodine does not inhibit CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, or 3A4, or induce CYP1A2, 2B6, 2C9, 2C19, or 3A4 at clinically relevant plasma concentrations.
Danish: In vitro-data viser, at fesoterodins aktive metabolit ikke hæmmer CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1 eller 3A4 eller inducerer CYP1A2, 2B6, 2C9, 2C19 eller 3A4 ved klinisk relevante plasmakoncentrationer.
English: - if you have an infection of the urinary tract, your doctor may need to prescribe some antibiotics
Danish: • hvis du har en urinvejsinfektion, kan lægen være nødt til at udskrive antibiotika til dig.
English: You should not take TOVIAZ if you are pregnant, as the effects of fesoterodine on pregnancy and the unborn baby are not known.
Danish: Du må ikke tage TOVIAZ, hvis du er gravid, da man ikke ved, hvordan fesoterodin virker på graviditet eller det ufødte barn.
English: In patients with a combination of these factors, additional exposure increases are expected.
Danish: Patienter med en kombination af disse faktorer må forventes at være yderligere eksponerede for den aktive metabolit.
English: After single or multiple-dose oral administration of fesoterodine in doses from 4 mg to 28 mg, plasma concentrations of the active metabolite are proportional to the dose.
Danish: Efter oral administration af fesoterodin som enkelteller flerdosis i doser fra 4 mg til 28 mg er plasmakoncentrationerne af den aktive metabolit proportional med dosis.
English: In addition, TOVIAZ is also available in HDPE bottles containing 30 or 90 tablets.
Danish: Desuden findes TOVIAZ også i HDPE-beholdere med 30 eller 90 tabletter.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Danish: Fortæl altid lægen eller på apoteket, hvis du tager anden medicin, har gjort det for nylig eller påtænker at tage anden medicin.
English: (1) Mild GFR = 50-80 ml/min; Moderate GFR = 30-50 ml/min; Severe GFR = <30 ml/min (2) Cautious dose increase.
Danish: Kontraindiceret (1) Let: GFR = 50-80 ml/min; moderat: GFR = 30-50 ml/min; svær GFR ≤30 ml/min (2) Dosis øges forsigtigt.
English: TOVIAZ can cause blurred vision, dizziness, and sleepiness.
Danish: TOVIAZ kan forårsage synsforstyrrelser, svimmelhed og søvnighed.
English: • Toxic megacolon.
Danish: • Toksisk megacolon
English: In the presence of fesoterodine there are no changes in the plasma concentrations of combined oral contraceptives containing ethinylestradiol and levonorgestrel.
Danish: Ved brug af fesoterodin er der ingen ændringer i plasmakoncentrationerne for kombinations-P-piller, som indeholder ethinylestradiol og levonorgestrel.
English: In animal reproduction studies, oral administration of fesoterodine to pregnant mice and rabbits during organogenesis resulted in fetotoxicity at maternal exposures that were 6 and 3 times the maximum recommended human dose (MRHD), respectively, based on AUC (see section 5.3).
Danish: I dyrereproduktionsstudier resulterede oral administration af fesoterodin til gravide mus og kaniner under organogenese i føtotoksicitet ved maternelle eksponeringer, som var henholdsvis 6 og 3 gange den maksimale anbefalede humane dosis (MRHD - Maximum Recommended Human Dose) baseret på AUC (se pkt.
English: A clinical study in healthy volunteers has shown that fesoterodine 8 mg once daily has no significant effect on the pharmacokinetics or the anticoagulant activity of a single dose of warfarin.
Danish: Et klinisk forsøg med raske forsøgspersoner har vist, at fesoterodin 8 mg én gang dagligt ikke har nogen signifikant virkning på farmakokinetikken eller den koagulationshæmmende virkning af en enkelt dosis warfarin.
English: The table below gives the frequency of treatment emergent adverse reactions from placebocontrolled clinical trials and from post-marketing experience.
Danish: Nedenstående tabel viser hyppigheden af bivirkninger, som forekom under behandlingen i placebokontrollerede kliniske undersøgelser og efter markedsføring.
English: See sections 4.3, 4.4 and 4.5
Danish: 4.3, 4.4 og 4.5
English: The efficacy of fixed doses of fesoterodine 4 mg and 8 mg was evaluated in two Phase 3 randomised, double-blind, placebo-controlled, 12-week studies.
Danish: Virkningen af fast doseret fesoterodin 4 mg og 8 mg blev evalueret i to randomiserede, dobbeltblinde, placebokontrollerede fase 3-undersøgelser af 12-ugers varighed.
English: Due to the pharmacological properties of fesoterodine, treatment may cause mild to moderate antimuscarinic effects like dry mouth, dry eye, dyspepsia and constipation.
Danish: På grund af fesoterodins farmakologiske egenskaber kan behandlingen give lette til moderate antimuskarine virkninger som mundtørhed, tørre øjne, dyspepsi og forstoppelse.
English: Fesoterodine may reduce the effect of medicinal products that stimulate the motility of the gastro-intestinal tract, such as metoclopramide.
Danish: Fesoterodin kan nedsætte virkningen af lægemidler, der stimulerer motiliteten af mavetarmkanalen, f.eks. metoclopramid.
English: If you forget to take a tablet, take your tablet as soon as you remember, but do not take more than one tablet in one day.
Danish: Hvis du glemmer at tage en tablet, skal du tage tabletten, så snart du kommer i tanke om det.
English: TOVIAZ is indicated in adults for treatment of the symptoms (increased urinary frequency and/or urgency and/or urgency incontinence) that may occur with overactive bladder syndrome.
Danish: TOVIAZ er indiceret hos voksne til behandling af de symptomer (hyppig vandladning og/eller imperiøs vandladningstrang og/eller urgeinkontinens), som kan forekomme med overaktiv blære.
English: The active metabolite is further metabolised in the liver to its carboxy, carboxy-N-desisopropyl, and N-desisopropyl metabolite with involvement of CYP2D6 and CYP3A4.
Danish: Den aktive metabolit metaboliseres yderligere i leveren til carboxyl-, carboxyl-N-desisopropyl- og N-desisopropylmetabolitter med involvering af CYP2D6 og CYP3A4.
English: Fesoterodine treated patients had statistically significant mean reductions in the number of micturitions per 24 hours and in the number of urge incontinence episodes per 24 hours at the end of treatment compared to placebo.
Danish: De patienter, der blev behandlet med fesoterodin havde statistisk signifikant gennemsnitlig reduktion i antallet af vandladninger pr. 24 timer og i antallet af episoder med urgeinkontinens pr. 24 timer ved behandlingens afslutning sammenlignet med patienterne, der fik placebo.
English: Based on how you respond to the medicine, your doctor may prescribe you a higher dose; one 8 mg tablet a day.
Danish: Alt efter hvordan du reagerer på medicinen, kan lægen ordinere en højere dosis på 1 TOVIAZ 8 mg tablet dagligt.
English: If you stop taking TOVIAZ
Danish: Hvis du holder op med at tage TOVIAZ
English: Pharmacotherapeutic group: Urologicals, Urinary antispasmodics, ATC code: G04BD11.
Danish: Farmakoterapeutisk klassifikation: Urologisk spasmolytikum, ATC-kode: G04BD11
English: Co-administration of a potent CYP2D6 inhibitor may result in increased exposure and adverse events.
Danish: Samtidig anvendelse af en potent CYP2D6-hæmmere kan resultere i øget eksponering og bivirkninger.
English: Caution should be exercised when prescribing or uptitrating fesoterodine to patients in whom an increased exposure to the active metabolite (see section 5.1) is expected:
Danish: Der bør udvises forsigtighed ved behandling af eller optitrering af dosis til patienter, der forventes at være mere eksponerede for den aktive metabolit (se pkt.
English: • The active substance is fesoterodine fumarate.
Danish: • Aktivt stof: fesoterodinfumarat.
English: Tachycardia; Palpitations
Danish: Takykardi; palpitationer
English: Angioedema; Urticaria
Danish: Angioødem; urticaria
English: What you need to know before you take TOVIAZ
Danish: Det skal du vide, før du begynder at tage TOVIAZ
English: Angioedema has been reported with fesoterodine and has occurred after the first dose in some cases.
Danish: Der er set angioødem ved brug af fesoterodin, i nogle tilfælde opstået efter den første dosis.
English: • Severe ulcerative colitis
Danish: • Svær colitis ulcerosa
English: Urinary retention may occur uncommonly.
Danish: Urinretention kan opstå i sjældne tilfælde.
English: Dysgeusia; Somnolence
Danish: Dysgeusi; søvnighed
English: At 45 mg/kg/day, a lower number of corpora lutea, implantation sites and viable foetuses was observed in female mice administered fesoterodine for 2 weeks prior to mating and continuing through day 7 of gestation.
Danish: Ved 45 mg/kg/dag sås der et lavere antal corpora lutea, antal implantationssteder og antal levedygtige fostre hos hunner, som fik fesoterodin i to uger inden parring og med fortsættelse indtil dag 7 i drægtighedsperioden.
English: If angioedema occurs, fesoterodine should be discontinued and appropriate therapy should be promptly provided.
Danish: Hvis angioødem opstår, skal behandlingen med fesoterodin seponeres og passende behandling straks påbegyndes.
English: The recommended starting dose is 4 mg once daily.
Danish: Den anbefalede startdosis er 4 mg 1 gang dagligt.
English: What TOVIAZ contains
Danish: TOVIAZ indeholder
English: Dose dependent antimuscarinic adverse reactions are likely to occur.
Danish: Dosisafhængige antimuskarine bivirkninger må forventes at forekomme.
English: This may lead to a greater risk of dental caries.
Danish: Mundtørhed giver en øget risiko for huller i tænderne.
English: The coating: polyvinyl alcohol, titanium dioxide (E171), macrogol (3350), talc, soya lecithin, indigo carmine aluminium lake (E132).
Danish: Overtræk: polyvinylalkohol, titandioxid (E171), macrogol (3350), talcum, sojalecithin, indigotin I (E132).
English: • Uncontrolled narrow angle glaucoma
Danish: • Ukontrolleret snævervinklet glaukom
English: The tablet core: xylitol, lactose monohydrate, microcrystalline cellulose, hypromellose, glycerol dibehenate, talc.
Danish: Tabletkerne: xylitol, laktosemonohydrat, mikrokrystallinsk cellulose, hypromellose, glyceroldibehenat, talcum.
English: • difficulty sleeping (insomnia)
Danish: • søvnbesvær (søvnløshed)
English: Electrocardiograms were obtained from 782 patients treated with 4 mg, 785 treated with 8 mg, 222 treated with 12 mg fesoterodine and 780 with placebo.
Danish: Der blev taget elektrokardiogram af 782 patienter, som blev behandlet med 4 mg fesoterodin, af 785 patienter, som blev behandlet med 8 mg fesoterodin, af 222 patienter, som blev behandlet med 12 mg fesoterodin, og af 780 personer, som fik placebo.
English: • Concomitant use of potent CYP3A4 inhibitors in subjects with moderate to severe hepatic or renal impairment
Danish: • Samtidig brug af potente CYP3A4-hæmmere hos patienter med svært nedsat lever- eller nyrefunktion
English: • confusion
Danish: • konfusion
English: TOVIAZ contains lactose and soya oil
Danish: TOVIAZ indeholder lactose og sojaolie
English: Based on AUC, the systemic exposure was 0.6 to 1.5 times higher in mice than in humans at the MRHD, whereas based on peak plasma concentrations, the exposure in mice was 5 to 9 times higher.
Danish: På baggrund af AUC er den systemiske eksponering 0,6-1,5 gange højere hos mus end hos mennesker ved MRHD (Maximum Recommended Human Dose), hvorimod eksponering hos mus på baggrund af maksimal plasmakoncentration er 5-9 gange højere.
English: TOVIAZ 4 mg and 8 mg tablets are packed in aluminium-aluminium blisters in cartons containing 7, 14, 28, 30, 56, 84, 98 or 100 tablets.
Danish: TOVIAZ 4 mg og 8 mg tabletter er pakket i aluminium-aluminium-blistere i æsker med 7, 14, 28, 30, 56, 84, 98 eller 100 tabletter.
English: Urinary retention (including feeling of residual urine; micturition disorder);
Danish: Urinretention (herunder følelse af resturin, miktionslidelser); igangsætningsbesvær ved vandladning
English: If you forget to take TOVIAZ
Danish: Hvis du har glemt at tage TOVIAZ
English: Voided volume per micturition (ml)
Danish: Udtømt mængde pr. vandladning (ml)
English: Microcrystalline cellulose Hypromellose Glycerol dibehenate Talc
Danish: Lactosemonohydrat Mikrokrystallinsk cellulose Hypromellose Glyceroldibehenat Talcum
English: In addition, TOVIAZ 4 mg and 8 mg tablets are also packed in HDPE bottles containing 30 or 90 tablets.
Danish: Desuden er TOVIAZ 4 mg og 8 mg tabletter også pakket i HDPEbeholdere med 30 eller 90 tabletter.
English: No dosing adjustments are recommended in the presence of moderate CYP3A4 inhibitors (e.g., erythromycin, fluconazole, diltiazem, verapamil and grapefruit juice).
Danish: Dosisjustering anbefales ikke ved tilstedeværelse af moderate CYP3A4-hæmmere (f.eks. erythromycin, fluconazol, diltiazem, verapamil og grapefrugtjuice).
English: TOVIAZ is available in blister packs of 7, 14, 28, 30, 56, 84, 98 and 100 prolonged-release tablets.
Danish: TOVIAZ fås i blisterpakninger med 7, 14, 28, 30, 56, 84, 98 eller 100 depottabletter.