FrancophonIA/ELRC3.0 huggingface dataset:
English: • Certain anti-psychotics such as chlorpromazine, flupenthixol, thoridazine, clozapine and risperidone.
Croatian: • određeni antipsihotici poput klorpromazina, flupentiksola, toridazina, klozapina i risperidona.
English: Sodium hydroxide (for pH adjustment) Hydrochloric acid (for pH adjustment) Water for injections
Croatian: 6.1 Popis pomoćnih tvari natrijev klorid natrijev hidroksid (za podešavanje pH) kloridna kiselina (za podešavanje pH) voda za injekcije
English: You will have to inject Ceplene and IL-2 twice a day by subcutaneous injection (in the layer of tissue just under the skin), according to the directions provided by your doctor.
Croatian: Ceplene i IL-2 ćete supkutanom injekcijom (u sloj tkiva odmah ispod kože) morati ubrizgavati dvaput na dan, prema uputama koje Vam je dao liječnik.
English: PREPARATION FOR INJECTION OF CEPLENE
Croatian: PRIPREMA ZA UBRIZGAVANJE CEPLENEA
English: • Rapid heart beat (tachycardia)
Croatian: • ubrzani otkucaji srca (tahikardija)
English: • Headache and dizziness
Croatian: • glavobolja i omaglica
English: Date of first authorisation: Date of latest renewal:
Croatian: Datum prvog odobrenja: Datum posljednje obnove odobrenja: 26.08.2013
English: Treatment with Ceplene in conjunction with IL-2 should be used with caution in patients with poorly compensated cardiac function.
Croatian: Liječenje Cepleneom u kombinaciji s IL-2 u bolesnika sa slabo kompenziranom funkcijom srca mora se primjenjivati s oprezom.
English: The vials contain 0.70 mL of solution (including overfill) to facilitate the dose extraction of a single 0.5 mL dose.
Croatian: Bočica sadrži 0,70 ml otopine (uključujući prepunjenje) čime se omogućuje vađenje jedne doze od 0,5 ml.
English: While posology differs, when Ceplene is used in conjunction with IL-2, physicians should also refer to the Summary of Product Characteristics (SmPC) for IL-2 and observe the respective medicinal product interactions.
Croatian: Iako se doziranje razlikuje, kada se Ceplene primjenjuje u kombinaciji s IL-2, liječnici moraju pogledati i sažetak opisa svojstava lijeka za IL-2 te paziti i na interakcije tog lijeka.
English: • Drying-out of the body (dehydration)
Croatian: • smanjenje količine tjelesne vode (dehidracija)
English: Histamine is rapidly absorbed after subcutaneous injection.
Croatian: Nakon supkutanog injiciranja, histamin se brzo apsorbira.
English: Ceplene must be injected 1 to 3 minutes after IL-2.
Croatian: Ceplene se mora ubrizgavati 1 do 3 minute nakon IL-2.
English: Ceplene is administered 1 to 3 minutes after each injection of IL-2.
Croatian: Ceplene se primjenjuje 1 do 3 minute nakon svake injekcije IL-2.
English: Clear, colourless aqueous solution.
Croatian: Bistra, bezbojna vodena otopina.
English: Patients with renal impairment may be more sensitive to the blood pressure lowering effects of Ceplene.
Croatian: Bolesnici s oštećenjem funkcije bubrega mogu biti osjetljiviji na Cepleneov učinak snižavanja krvnog tlaka.
English: Dispensing instructions for IL-2 (aldesleukin)
Croatian: Upute za izdavanje za IL-2 (aldesleukin)
English: Ceplene and IL-2 must not be injected into the same region.
Croatian: Ceplene i IL-2 ne smiju se ubrizgati na isto područje.
English: w.13 to w.15 (Days 1-21)
Croatian: 13. do 15. tjedan (1.-21. dan)
English: - H2 blockers such as cimetidine, ranitidine, famotidine or nizatidine which are used to treat stomach ulcers, indigestion (dyspepsia) or heartburn.
Croatian: - H2 blokatore poput cimetidina, ranitidina, famotidina ili nizatidina koji se koriste za liječenje čireva u želucu, probavnih tegoba (dispepsije) ili žgaravice.
English: Treatment can be resumed by administering Ceplene at the full dose and IL-2 at 50%.
Croatian: Liječenje se može nastaviti primjenom pune doze Ceplenea i 50% doze IL-2.
English: Ceplene should be administered 1 to 3 minutes after IL-2 administration, and not concomitantly.
Croatian: Ceplene se mora primjenjivati 1 do 3 minute nakon primjene IL-2, a ne istodobno.
English: They are used to inhibit activity of the immune system (immunosuppressant) and to reduce inflammation (see above “Do not use Ceplene”).
Croatian: Oni se uzimaju za inhibiranje aktivnosti imunološkog sustava (imunosupresivi) i smanjenje upale (pogledajte gore navedeno
English: Ceplene 0.5 mg/0.5 mL solution for injection
Croatian: Ceplene 0,5 mg/0,5 ml otopina za injekciju
English: 2 mL type I glass vial, with bromobutyl rubber stopper and flip-off aluminium over seal, containing 0.5 mL of solution (0.70 mL including overfill).
Croatian: Bočica od stakla tip I od 2 ml, s bromobutilnim gumenim čepom i odvojivim aluminijskim zatvaračem, sadrži 0,5 ml otopine (0,70 ml uključujući prepunjenje).
English: • Tricyclic antidepressant medicines such as amitryptiline, imipramine, or monoamine oxidase inhibitors, such as phenelzine, isocarboxazide, tranylcypromine or moclobemide.
Croatian: • triciklički antidepresivi poput amitriptilina, imipramina ili inhibitora monoaminooksidaze, poput fenelzina, izokarboksazida, tranilcipromina ili moklobemida.
English: • bleeding ulcers,
Croatian: • čirevi koji krvare,
English: How to take Ceplene
Croatian: Kako uzimati Ceplene
English: • Hives, bruising, rash and swelling at the injection site, weakness (asthenia) and chest pain
Croatian: • koprivnjača, stvaranje modrica, osip i oticanje na mjestu ubrizgavanja, slabost (astenija) i bol u prsištu
English: • H2 blockers such as cimetidine, ranitidine, famotidine or nizatidine.
Croatian: • H2 blokatori poput cimetidina, ranitidina, famotidina ili nizatidina.
English: w.7 to w.9 (Days 1-21)
Croatian: 7. do 9. tjedan (1.-21. dan)
English: There is no information about the use of Ceplene in pregnant women.
Croatian: Nema podataka o primjeni Ceplenea kod trudnica.
English: For cycles 4-10, each cycle consists of 3 weeks of treatment, followed by a 6-week treatment free period.
Croatian: Kod 4. do 10. ciklusa, svaki se ciklus sastoji od 3 tjedna liječenja, nakon čega slijedi 6tjedno razdoblje bez liječenja.
English: • Patients who have received an allogenic stem cell transplant.
Croatian: • Bolesnici kojima su presađene alogene matične stanice.
English: Women of childbearing potential and sexually active men must use effective methods of contraception during treatment with Ceplene and IL-2.
Croatian: Žene u reproduktivnoj dobi i seksualno aktivni muškarci tijekom liječenja Cepleneom i IL-2 moraju koristiti učinkovite metode kontracepcije.
English: Thus, subjects with severe renal impairment may be more sensitive to the blood pressure lowering effects of exogenously administered histamine than subjects with normal renal function or subjects with mild or moderate renal impairment.
Croatian: Stoga, ispitanici s teškim oštećenjem funkcije bubrega mogu biti osjetljiviji na učinke sniženja krvnog tlaka egzogeno primijenjenog histamina od ispitanika s normalnom funkcijom bubrega ili ispitanika s blagom do umjereno oštećenom funkcijom bubrega.
English: For cycles 1-3, each cycle consists of 3 weeks of treatment, followed by a 3-week treatment free period.
Croatian: Kod 1. do 3. ciklusa, svaki se ciklus sastoji od 3 tjedna liječenja, nakon čega slijedi 3-tjedno razdoblje bez liječenja.
English: Withdraw and discard the syringe as instructed.
Croatian: Izvucite štrcaljku i bacite prema uputama.
English: For instructions on the initial reconstitution and subsequent dilution to 200 µg/mL of Interleukin-2 (aldesleukin) before administration, see commercially available IL-2 SmPC.
Croatian: Za upute o početnoj rekonstituciji i daljnjem razrjeđivanju na 200 µg/ml interleukina-2 (aldesleukina) prije primjene, vidjeti komercijalno dostupan sažetak opisa svojstava lijeka za IL-2.
English: • For the following 63 weeks: you will use IL-2 and Ceplene daily for 3 weeks, followed by a
Croatian: • prvih 18 tjedana: IL-2 i Ceplene primjenjivat ćete svakodnevno kroz 3 tjedna, nakon čega slijedi
English: Ceplene and IL-2 are not to be injected at the same time.
Croatian: Ceplene i IL-2 ne smiju se ubrizgavati u isto vrijeme.
English: Periodic Safety Update Reports
Croatian: Periodička izvješća o neškodljivosti
English: If you have liver problems, talk to your doctor before using this medicine.
Croatian: Ako imate problema s jetrom, prije uzimanja ovog lijeka obratite se svom liječniku.
English: It is provided in a glass vial with a grey rubber stopper and a blue peel flip off aluminium tamper evident over seal.
Croatian: Isporučuje se u staklenoj bočici sa sivim gumenim čepom i plavim odvojivim aluminijskim zatvaračem s evidencijom otvaranja.
English: INSTRUCTIONS FOR SELF-INJECTION OF CEPLENE
Croatian: UPUTE ZA SAMOINJICIRANJE CEPLENEA
English: • Bloating of the belly (abdominal distension)
Croatian: • nadimanje trbuha (distenzija abdomena)
English: Blood and lymphatic system disorders eosinophilia, thrombocytopenia Very common leucopenia, neutropenia
Croatian: Poremećaji krvi i limfnog sustava eozinofilija, trombocitopenija vrlo često leukopenija, neutropenija često
English: • Decrease in the number of white blood cells (leucopenia)
Croatian: • smanjenje broja bijelih krvnih stanica (leukopenija)
English: Figure 1
Croatian: Slika 1
English: Although the degree of renal impairment has little effect on the PK disposition of histamine, caution should be used in the administration of histamine to patients with severe renal impairment.
Croatian: Iako stupanj oštećenja funkcije bubrega ima mali učinak na PK raspoloživost histamina, kod primjene histamina u bolesnika s teškim oštećenjem funkcije bubrega potreban je oprez.
English: If you are taking any of the following medicines, please be sure to discuss this with your doctor or pharmacist before using Ceplene.
Croatian: Ako uzimate bilo koji od sljedećih lijekova, prije primjene Ceplenea molimo o tome porazgovarajte sa svojim liječnikom ili ljekarnikom.
English: • Infections of the upper breathing (respiratory) tract
Croatian: • infekcije gornjih dišnih puteva
English: Metabolism and nutrition disorders decreased appetite
Croatian: Poremećaji metabolizma i prehrane smanjen apetit vrlo često dehidracija često
English: If you have kidney problems, talk to your doctor before using this medicine.
Croatian: Ako imate problema s bubrezima, prije uzimanja ovog lijeka obratite se svom liječniku.
English: • Nausea, indigestion (dyspepsia) and diarrhoea
Croatian: • mučnina, probavne tegobe (dispepsija) i proljev
English: • Inflammation of the stomach (gastritis)
Croatian: • upala želuca (gastritis)
English: • Wheezing
Croatian: • piskanje
English: Up to two weeks supply of pre-filled capped tuberculin syringes may be provided to patients for home administration, with instructions that the syringes be stored under refrigeration at 2°C - 8°C prior to administration.
Croatian: Bolesnicima se za primjenu kod kuće smije izdati najviše dvotjedna zaliha napunjenih tuberkulinskih štrcaljki sa zatvaračem uz upute da se prije primjene te štrcaljke moraju čuvati u hladnjaku na 2°C8°C.
English: Ceplene should be used with caution in patients with moderate to severe hepatic impairment (see section 5.2).
Croatian: Ceplene se u bolesnika s umjerenim do teškim oštećenjem funkcije jetre (vidjeti dio 5.2) mora oprezno primjenjivati.
English: (hypothyroidism)
Croatian: (pruritus)
English: • For the first 18 weeks: you will use IL-2 and Ceplene daily for 3 weeks, followed by a 3 week break (no treatment at all).
Croatian: • sljedeća 63 tjedna: IL-2 i Ceplene primjenjivat ćete svakodnevno kroz 3 tjedna, nakon čega slijedi 6 tjedana prekida (bez liječenja).
English: General disorders and administration site conditions injection site granuloma, fatigue, pyrexia, injection site erythema, feeling hot, injection site reaction, injection site pruritus, influenza like illness, chills, injection site inflammation, injection site pain
Croatian: Opći poremećaji i reakcije na mjestu primjene granulom na mjestu injiciranja, umor, pireksija, eritem na mjestu injiciranja, osjećaj vrućine, reakcija na mjestu injiciranja, svrbež na mjestu injiciranja, bolest nalik gripi, zimica, upala na mjestu injiciranja, bol na mjestu injiciranja vrlo često urtikarija na mjestu injiciranja, stvaranje modrica na mjestu injiciranja, osip na mjestu injiciranja, oticanje na mjestu injiciranja, astenija, bol u prsima često
English: Nervous system disorders paraesthesia
Croatian: Poremećaji živčanog sustava parestezija često
English: • Nasal congestion
Croatian: • navale crvenila
English: Figure 5
Croatian: Slika 5
English: How to store Ceplene
Croatian: Kako primjenjivati Ceplene
English: Plasma Ceplene levels are higher in patients with moderate and severe liver impairment, and these patient groups tend to experience more tachycardia and lower blood pressure after Ceplene dosing than do patients with normal or mildly affected liver function.
Croatian: Razine Ceplenea u plazmi više su u bolesnika s umjerenim do teškim oštećenjem funkcije jetre te su, za razliku od bolesnika s normalnom ili blago oštećenom funkcijom jetre, ove skupine bolesnika sklonije tahikardiji i nižem krvnom tlaku nakon primjene doze Ceplenea.
English: Dose reduction of Ceplene is normally not required in hepatically impaired patients, but caution should be used in these patients.
Croatian: U bolesnika s oštećenjem jetre obično nije potrebno smanjiti dozu Ceplenea, no potreban je oprez.
English: Ask your doctor if you have any questions about Ceplene or IL-2.
Croatian: Ako imate bilo kakvih pitanja o Cepleneu ili IL-2, upitajte svog liječnika.
English: For instructions on reconstitution and dilution of Interleukin-2 (aldesleukin) before administration, see commercially available IL-2 SmPC.
Croatian: Za upute o rekonstituciji i razrjeđivanju interleukina-2 (aldesleukina) prije primjene vidjeti komercijalno dostupan sažetak opisa svojstava lijeka za IL-2.
English: Infections and infestations upper respiratory tract infections
Croatian: Infekcije i infestacije infekcije gornjih dišnih putova vrlo često pneumonija često
English: Figure 2
Croatian: Slika 2
English: They are used to treat stomach ulcers, indigestion (dyspepsia) or heartburn (see above “Do not use Ceplene”).
Croatian: Koriste se za liječenje čireva želuca, probavnih tegoba (dispepsija) ili žgaravice (pogledajte gore navedeno
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE Bočica
English: Treatment should then be resumed using the full dose of Ceplene, but reducing the IL-2 dose by 20%.
Croatian: Liječenje je zatim potrebno nastaviti uz punu dozu Ceplenea, no uz smanjenje doze IL-2 za
English: For persistent hypotension, headache, arrhythmia, cardiac, hepatic and renal toxicities - the time of injection of the dose of Ceplene should be extended to a maximum of 15 minutes.
Croatian: Kod ustrajne hipotenzije, glavobolje, aritmije, kardijalne, hepatične i renalne toksičnosti - vrijeme injiciranja doze Ceplenea mora se produljiti na maksimalno 15 minuta. - količinu doze Ceplenea i IL-2 potrebno je smanjiti za 20%.
English: • During breast feeding.
Croatian: • Tijekom dojenja.
English: A maximum delay of one treatment cycle can be considered for the resolution of grade 3 and 4 events.
Croatian: Za povlačenje toksičnosti stupnja 3 i 4, može se razmotriti maksimalna odgoda jednog ciklusa liječenja.
English: Pull the needle cover straight off. With the vial standing on a flat surface, insert the needle straight through the rubber stopper into the vial.
Croatian: Dok je bočica na ravnoj površini, iglu umetnite ravno kroz gumeni čep u bočicu.
English: • Cough, difficulty in breathing (dyspnoea)
Croatian: • kašalj, otežano disanje (dispneja)
English: See Figure 1.
Croatian: Vidjeti sliku 1.
English: Table 3: Administration chart for IL-2 (aldesleukin)
Croatian: Tablica 3: Tablica za primjenu IL-2 (aldesleukina)
English: Psychiatric disorders insomnia
Croatian: Psihijatrijski poremećaji nesanica često
English: NOTE: The vial of Ceplene contains an overfill to facilitate the dose extraction of a single 0.5 mL dose.
Croatian: Bočica Ceplenea sadrži veću količinu otopine od potrebnog, čime se omogućuje izvlačenje jedne doze od 0,5 ml.
English: One vial contains 0.5 mg histamine dihydrochloride in 0.5 mL solution.
Croatian: Jedna bočica sadrži 0,5 mg histamindiklorida u 0,5 ml otopine.
English: Therefore, the treatment with Ceplene and IL-2 must not be used during pregnancy.
Croatian: Stoga se Ceplene i IL-2 ne smiju primjenjivati tijekom trudnoće.
English: Ceplene 0.5 mg/0.5 mL solution for injection histamine dihydrochloride
Croatian: Ceplene 0,5 mg/0,5 ml otopina za injekciju histamindiklorid
English: 12 Take the needle out of the vial.
Croatian: Izvucite iglu iz bočice.
English: Subsequent injections of Ceplene may be self-administered at home by a patient who demonstrates a good understanding of necessary precautions and who has demonstrated adequate injection skills.
Croatian: Bolesnici koji su pokazali dobro razumijevanje nužnih mjera opreza i koji su pokazali odgovarajuće vještine injiciranja, sljedeće injekcije Ceplenea mogu primjenjivati sami, kod kuće.
English: Twice daily w.22
Croatian: 22. do tjedan
English: See Figure 6.
Croatian: Pogledajte sliku 6.
English: Figure 3
Croatian: Slika 3
English: Patients showed a higher degree of variability with respect to systemic exposure as compared to healthy subjects.
Croatian: U usporedbi sa zdravim dobrovoljcima, bolesnici su pokazali veći stupanj varijabilnosti spram sustavne izloženosti.
English: Figure 4
Croatian: Slika 4
English: For patients experiencing grade 2 (including cardiac function, renal, hepatic) toxicity - treatment should be discontinued until the event has returned to grade 1 - the time of injection of the dose of Ceplene should be extended to a maximum of 15 minutes.
Croatian: Za bolesnike sa stupnjem toksičnosti 2 (uključujući funkciju srca, bubrega, jetre) - liječenje se mora prekinuti do povrata na stupanj 1 - vrijeme injiciranja doze Ceplenea mora se produljiti na maksimalno 15 minuta. - za kardijalnu, hepatičnu i renalnu toksičnost, doza Ceplenea i IL-2 mora se smanjiti za 20%.
English: Figure 7
Croatian: Slika 7
English: Figure 6
Croatian: Slika 6
English: Gastrointestinal disorders constipation, abdominal distention, stomatitis
Croatian: Poremećaji probavnog sustava konstipacija, distenzija abdomena, stomatitis često
English: • Rash
Croatian: • osip
English: - Monoamine oxidase inhibitors and anti-malarial and anti-trypanosomal agents.
Croatian: Inhibitori monoaminooksidaze, djelatne tvari protiv malarije i protiv tripanosoma mogu izmjeniti metabolizam
English: See Figure 2.
Croatian: Vidjeti sliku 2.
English: See Figure 7.
Croatian: Pogledajte sliku 7.
English: Vascular disorders hot flush
Croatian: Krvožilni poremećaji navale vrućine često
English: to w.21
Croatian: U CR1
English: 10 Holding both the vial and the syringe, turn the vial upside down.
Croatian: Držeći i bočicu i štrcaljku, okrenite bočicu naopako.
English: (chills), injection site inflammation and pain.
Croatian: simptomi nalik gripi, drhtanje (zimica), upala na mjestu ubrizgavanja i bol.
English: • Inflamed granulated skin at the injection site, fatigue, fever (pyrexia), injection site redness,
Croatian: • upaljena granulirana koža na mjestu ubrizgavanja, umor, vrućica (pireksija), crvenilo na mjestu ubrizgavanja, osjećaj vrućine, reakcije na mjestu ubrizgavanja, svrbež na mjestu ubrizgavanja,
English: -for grade 1 to 3 toxicity, treatment should be discontinued until grade 0 toxicity event has been achieved.
Croatian: Za bolesnike sa stupnjem neurološke toksičnosti od 1-4 - za stupnjeve toksičnosti 1 do 3, liječenje se mora prekinuti dok se ne postigne stupanj toksičnosti 0.
English: One vial of 0.5 mL of solution contains 0.5 mg histamine dihydrochloride.
Croatian: Jedna bočica s 0,5 ml otopine sadrži 0,5 mg histamindiklorida.
English: Vascular disorders flushing, hypotension
Croatian: Krvožilni poremećaji navale crvenila, hipotenzija vrlo često
English: • Hot flushes
Croatian: • navale vrućine (valunzi)
English: Therefore Ceplene and IL-2 must not be used during breast-feeding.
Croatian: Stoga se Ceplene i IL-2 ne smiju primjenjivati tijekom dojenja.
English: • Sensation of spinning (vertigo)
Croatian: • osjećaj vrtnje (vrtoglavica)
English: Refer to the IL-2 SmPC for information on pregnancy and breast-feeding with IL-2.
Croatian: Za informacije o primjeni IL-2 tijekom trudnoće i dojenja pogledajte sažetak opisa svojstava lijeka za IL-2.
English: Inspect each vial visually for particulate matter and discolouration prior to administration.
Croatian: Prije primjene svaku bočicu vizualno pregledajte na prisutnost čestica i promjenu boje.
English: Cycle 1 Cycle 2 Cycle 3 w.1 to w.3 (Days 1-21)
Croatian: 1. do 3.tjedan (1.-21. dan)
English: The solution should be visually inspected for particulate matter and discolouration prior to administration.
Croatian: Prije primjene otopina se mora vizualno pregledati na prisutnost čestica i promjenu boje.
English: See Figure 3.
Croatian: Vidjeti sliku 3.
English: However, no Ceplene dose reduction is normally required in renally impaired patients.
Croatian: Međutim, u bolesnika s oštećenom funkcijom bubrega obično nije potrebno smanjiti dozu Ceplenea.
English: System organ class
Croatian: Klasifikacija organskih sustava Nuspojave
English: Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
Croatian: nuspojave su navedene prema ozbiljnosti, padajućim redoslijedom.
English: Very common erythema, hyperhidrosis, night sweats, pruritus
Croatian: Poremećaji kože i potkožnog tkiva osip vrlo često eritem, hiperhidroza, noćno znojenje, svrbež često
English: Treatment should then be resumed at a 20% dose reduction for both Ceplene and IL-2.
Croatian: Liječenje je zatim potrebno nastaviti uz 20% smanjenje doze Ceplenea i IL-2. - za toksičnost stupnja 4, potrebno je razmotriti prekid liječenja.
English: Adverse reactions were reported to be at least possibly related to IL-2 and Ceplene treatment in almost all patients in studies in AML.
Croatian: Tijekom ispitivanja AML-a, kod gotovo svih bolesnika zabilježene su nuspojave za koje je malo vjerojatno da su povezane s liječenjem IL-2 i Cepleneom.
English: Ear and labyrinth disorders vertigo
Croatian: Poremećaji uha i labirinta vrtoglavica često
English: Subcutaneous use only.
Croatian: Samo za supkutanu primjenu.
English: Psychiatric disorders anxiety
Croatian: Psihijatrijski poremećaji anksioznost vrlo često depresija često
English: Method
Croatian: Ciklusi
English: w.58
Croatian: 58. do tjedan
English: Patients receiving the following medicinal products should be treated with caution (see section 4.5): - Beta-blockers or other anti-hypertensive agents.
Croatian: Bolesnike koji primaju sljedeće lijekove mora se oprezno liječiti (vidjeti dio 4.5): - beta-blokatore ili druge antihipertenzive - blokatore H1 i neuroleptike (antipsihotike) sa svojstvima blokiranja H1 receptora - tricikličke antidepresive koji mogu imati svojstva blokiranja H1 i H2 receptora - inhibitore monoaminooksidaze te tvari protiv malarije i protiv tripanosoma - neuromuskularne blokatore, narkotičke analgetike i razna kontrastna sredstva.
English: Respiratory, thoracic, and mediastinal disorders wheezing
Croatian: Poremećaji dišnog sustava, prsišta i sredoprsja piskanje pri disanju često
English: Posology
Croatian: Kutija
English: w.37
Croatian: 37. do tjedan
English: w.73
Croatian: 73. do tjedan
English: w.76
Croatian: 76. do tjedan
English: w.67
Croatian: 67. do tjedan
English: w.55to w.57
Croatian: 55. do tjedan
English: Vial
Croatian: Doziranje
English: Ceplene should be administered in the clinic under supervision of the physician on day 1 of the initial treatment cycle.
Croatian: Na 1. dan pokretanja ciklusa liječenja, Ceplene se mora primjenjivati u klinici, pod nadzorom liječnika.
English: Method of administration
Croatian: NAČIN IZDAVANJA LIJEKA
English: Sodium chloride
Croatian: Samoinjiciranje Ceplenea
English: w.49
Croatian: 49. do tjedan
English: • stroke,
Croatian: • moždani udar,
English: w.64
Croatian: 64. do tjedan
English: Fever
Croatian: Dojenje
English: Ceplene in conjunction with IL-2 must not be used during pregnancy.
Croatian: Tijekom trudnoće, Ceplene se ne smije primjenjivati u kombinaciji s IL-2.