FrancophonIA/ELRC3.0 huggingface dataset:
English: Following injection with Natpar, serum phosphate levels decrease proportionally to PTH(1-84) levels over the first 4 hours and persist over 24 hours post-injection.
Croatian: Nakon injekcije lijeka Natpar, razine fosfata u serumu smanjuju se razmjerno razinama PTH-a(1-84) tijekom prva 4 sata i ostaju održane tijekom razdoblja od 24 sata nakon injekcije.
English: Talk to your doctor, pharmacist or nurse before using Natpar.
Croatian: Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego primijenite lijek Natpar.
English: Natpar should be used with caution in young adult patients with open epiphyses as these patients may be at increased risk for osteosarcoma (see section 4.3).
Croatian: Natpar treba primjenjivati uz oprez u mladih odraslih bolesnika s otvorenim epifizama, budući da ti bolesnici mogu biti izloženi povećanom riziku od osteosarkoma (vidjeti dio 4.3).
English: Each dose must be administered as a subcutaneous injection once a day in alternating thighs.
Croatian: Svaka doza mora biti primijenjena kao supkutana injekcija jedanput dnevno, svakog dana u drugo bedro.
English: It is available in 4 different strengths of pen (each pre-filled pen contains 14 doses): Natpar 25 micrograms
Croatian: Dostupan je u 4 različite jačine brizgalica (jedna napunjena brizgalica sadrži 14 doza): Natpar 25 mikrograma
English: Lower than 2 mmol/L
Croatian: Niže od 2 mmol/l
English: Check the dose counter to see if there are any doses left, or check the “Discard On” date on the Medicine Tracker to see if it has been more than 14 days.
Croatian: Provjerite na brojaču ima li preostalih doza i provjerite datum naveden pored „Baciti“ u Dnevniku zamjene brizgalice da vidite je li prošlo više od 14 dana.
English: Do not place the pen under water.
Croatian: Nemojte brizgalicu stavljati pod vodu.
English: • headaches*
Croatian: • glavobolje*
English: Then consider resuming Natpar, calcium and active vitamin D at lower doses (see sections 4.2 and 4.8).
Croatian: Zatim razmotrite nastavak primjene lijeka Natpar, kalcija i aktivnog vitamina D u nižim dozama (vidjeti dijelove 4.2 i 4.8).
English: EXP Discard mixed pen after 14 days.
Croatian: EXP Bacite brizgalicu s izmiješanim lijekom nakon 14 dana.
English: The goal of treatment with Natpar is to achieve calcaemic control and to reduce symptoms (see also section 4.4).
Croatian: Cilj liječenja lijekom Natpar je postići kontrolu kalcemije i smanjiti simptome (vidjeti također dio 4.4).
English: Non-interventional post-authorisation safety study (PASS): In order to collect long-term data on clinical efficacy and safety, the MAH should submit the results of a study based on data deriving from a registry of patients with hypoparathyroidism and who are treated with NATPAR.
Croatian: Neintervencijsko ispitivanje sigurnosti primjene lijeka nakon dobivanja odobrenja za stavljanje lijeka u promet (PASS): Za svrhe prikupljanja dugoročnih podataka o kliničkoj djelotvornosti i sigurnosti, nositelj odobrenja mora predati rezultate ispitivanja temeljene na podacima dobivenim iz registra bolesnika s hipoparatireoidizmom koji su liječeni lijekom NATPAR.
English: Concomitant use of Natpar with bisphosphonates is not recommended.
Croatian: Ne preporučuje se istodobna primjena lijeka Natpar s bisfosfonatima.
English: Important: To make capping easier, place the needle cap against an object or surface.
Croatian: Važno: Kako biste si olakšali vraćanje kapice na iglu, prislonite kapicu uz neki predmet ili površinu.
English: In the kidney, PTH (1-84) increases renal tubular reabsorption of calcium and promotes phosphate excretion.
Croatian: U bubrezima, PTH (1-84) povećava renalnu tubularnu reapsorpciju kalcija i potiče izlučivanje fosfata.
English: The safety and clinical efficacy of Natpar in adults with hypoparathyroidism is derived from 1 randomised, placebo-controlled study and an open-label extension study.
Croatian: Sigurnost i klinička djelotvornost lijeka Natpar u odraslih osoba s hipoparatiroidizmom izvedeni su iz jednog randomiziranog, placebom kontroliranog ispitivanja i jednog otvorenog nastavka ispitivanja.
English: System organ class
Croatian: Klasifikacija organskog sustava
English: If you stop using Natpar
Croatian: Ako prestanete primjenjivati Natpar
English: It is recommended to measure the albumin-corrected serum calcium 8-12 hours after dosing Natpar.
Croatian: Preporučuje se mjerenje kalcija u serumu korigiranog za albumin 8-12 sati nakon doziranja lijeka Natpar.
English: The cartridge is made of glass, with a rubber seal on top.
Croatian: Uložak je izrađen od stakla, s gumenom brtvom na vrhu.
English: Available pharmacology data in animals have shown excretion of Natpar in milk (see section 5.3).
Croatian: Dostupni farmakološki podaci u životinja pokazuju da se Natpar izlučuje u mlijeko (vidjeti dio 5.3).
English: The clinical study report should be submitted by:
Croatian: Izvješće o kliničkom ispitivanju treba dostaviti do:
English: It is strongly recommended that every time you receive a dose of Natpar, the name and batch number of the product are recorded in order to maintain a record of the batches used.
Croatian: Strogo se preporučuje da se svaki put kada dobijete dozu lijeka Natpar zabilježi naziv lijeka i broj serije lijeka kako bi se vodila evidencija o primijenjenim brojevima serije.
English: Weight No dose adjustment is necessary based on weight.
Croatian: Nije potrebno prilagođavanje doze na temelju tjelesne težine.
English: If your levels of parathyroid hormone are too low, you can have low blood calcium.
Croatian: Ako su Vaše razine paratiroidnog hormona preniske, možda imate nizak kalcij u krvi.
English: Can I re-use the pen needles?
Croatian: Smijem li više puta upotrijebiti igle brizgalice?
English: A new sterile needle must be used for every injection.
Croatian: Za svaku injekciju mora se koristiti nova sterilna igla.
English: You may need to take more calcium supplements if you have signs of low blood calcium; see section 4 for symptoms.
Croatian: Možda ćete trebati uzeti više nadomjestka kalcija ako imate znakove niske razine kalcija u krvi; vidjeti dio 4 za simptome.
English: • redness and pain at injection site
Croatian: • crvenilo i bol na mjestu injekcije
English: Your doctor will decide whether to start treatment with Natpar.
Croatian: Vaš liječnik će odlučiti treba li započeti liječenje lijekom Natpar.
English: Sodium chloride, mannitol, citric acid monohydrate, metacresol, sodium hydroxide (for pH adjustment), water for injections.
Croatian: Natrijev klorid, manitol, citratna kiselina hidrat, metakrezol, natrijev hidroksid (za podešavanje pH), voda za injekcije.
English: The apparent terminal half-life (t1/2) was 3.02 and 2.83 hours for the 50 and 100 micrograms dose, respectively.
Croatian: Prividni terminalni poluvijek (t1/2) bio je 3,02 i 2,83 sata za dozu od 50, odnosno 100 mikrograma.
English: Study 2 is a long-term, open-label extension study of daily subcutaneous dosing of Natpar in hypoparathyroidism patients who completed prior studies with Natpar.
Croatian: Ispitivanje 2 je dugoročni, otvoreni nastavak ispitivanja svakodnevnih doza supkutano primjenjivanog lijeka Natpar u bolesnika s hipoparatiroidizmom koji su dovršili prethodna ispitivanja s lijekom Natpar.
English: You can pinch a fold of the skin if told by your doctor or nurse.
Croatian: Možete prstima uhvatiti kožu u nabor ako su Vas tako uputili liječnik ili medicinska sestra.
English: A decision must be made whether to discontinue breast-feeding or to discontinue therapy with Natpar, taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Croatian: Mora se odlučiti da li prekinuti dojenje ili prekinuti liječenje lijekom Natpar uzimajući u obzir korist dojenja za dijete i korist liječenja za ženu.
English: Distribution Following intravenous administration, Natpar has a volume of distribution of 5.35 L at steady state.
Croatian: Nakon intravenske primjene, Natpar ima volumen distribucije od 5,35 l u stanju dinamičke ravnoteže.
English: The most frequent adverse reactions among patients treated with Natpar were hypercalcaemia, hypocalcaemia, and their associated clinical manifestations including headache, diarrhoea, vomiting, paraesthesia, hypoaesthesia and hypercalciuria.
Croatian: Najčešće nuspojave među bolesnicima liječenima lijekom Natpar bile su hiperkalcemija, hipokalcemija i njihove povezane kliničke manifestacije uključujući glavobolju, dijareju, povraćanje, paresteziju, hipoesteziju i hiperkalciuriju.
English: You may have forgotten to prime the pen as instructed in “New Pen Setup & Mixing” (Section B).
Croatian: Možda ste zaboravili napuniti brizgalicu kako je opisano u uputama pod naslovom „Priprema nove brizgalice i miješanje lijeka” (dio B).
English: Consider reducing or stopping Natpar and re-assess by means of serum calcium measurement
Croatian: Razmotrite smanjivanje ili prekid primjene lijeka Natpar i napravite ponovnu procjenu mjerenjem kalcija u serumu
English: Do not use the Natpar Pre-filled Pen unless you have been shown the right way to give the injections by a doctor or nurse.
Croatian: Nemojte upotrijebiti Natpar napunjenu brizgalicu ako Vam liječnik ili medicinska sestra nisu pokazali pravilan način injiciranja lijeka.
English: If serum concentration of 25-OH vitamin D is low then appropriate supplementation may restore serum calcium response to Natpar (see section 4.2).
Croatian: Ako je koncentracija 25-OH vitamina D u serumu niska, tada prikladni nadomjestak može ponovno uspostaviti odgovor kalcija u serumu na Natpar (vidjeti dio 4.2).
English: 11 • Check if the yellow dose counter lines up with the number “14” (See Figure L).
Croatian: 11. • Provjerite je li žuta oznaka brojača doza u ravnini s brojem „14“ (pogledajte sliku L).
English: Natpar is a synthetic form of parathyroid hormone that helps you keep calcium and phosphate levels in your blood and urine at a normal level.
Croatian: Natpar je sintetički oblik paratiroidnog hormona koji Vam pomaže održavati razine kalcija i fosfata u krvi i urinu na normalnoj razini.
English: The risk for serious hypocalcaemia is highest after Natpar is withheld, missed or abruptly discontinued, but can occur at any time.
Croatian: Rizik od ozbiljne hipokalcemije najveći je nakon što se primjena lijeka Natpar prekine, ako se lijek propusti uzeti ili se s njegovom primjenom naglo prestane, ali može se pojaviti bilo kada.
English: Consistent with the potentially immunogenic properties of medicinal products containing peptides, administration of Natpar may trigger the development of antibodies.
Croatian: Zbog potencijalno imunogenih svojstava lijekova koji sadrže peptide, primjena lijeka Natpar može izazvati razvoj antitijela.
English: The overall effect of PTH is to increase serum calcium concentration, to reduce urinary excretion of calcium and to lower serum phosphate concentration.
Croatian: Ukupni učinak PTH-a je povećavanje koncentracije kalcija u serumu, smanjivanje urinarnog izlučivanja kalcija i smanjivanje koncentracije fosfata u serumu.
English: Parathyroid hormone receptors belong to the family of G-coupled protein receptors.
Croatian: Receptori paratiroidnog hormona spadaju u obitelj receptora spregnutih s G proteinima.
English: 1 • Check the expiration date (EXP) on the pen (See Figure A).
Croatian: 1. • Provjerite rok valjanosti (EXP) na brizgalici (pogledajte sliku A).
English: Important: If the cartridge is hard to screw down all the way, tighten the needle and try to slowly screw down the cartridge again.
Croatian: Važno: Ako je uložak teško zakrenuti do kraja, zategnite iglu i ponovno pokušajte polaganim zakretanjem pričvrstiti uložak.
English: • Let the injection site air dry.
Croatian: • Pustite da se to područje osuši.
English: If pre-dose serum calcium is >2.25 mmol/L, a starting dose of 25 micrograms can be considered.
Croatian: Ako je prije primjene doze kalcij u serumu >2,25 mmol/l, treba razmotriti početnu dozu od 25 mikrograma.
English: Co-administration of alendronic acid and Natpar may lead to a reduction in the calcium sparing effect, which can interfere with the normalisation of serum calcium.
Croatian: Istodobna primjena alendronatne kiseline i lijeka Natpar može dovesti do smanjenja učinka štednje kalcija, što može ometati normalizaciju razine kalcija u serumu.
English: • tingling and numbness of the skin
Croatian: • trnci i utrnulost kože
English: • Get a new pen needle and set it next to the pen.
Croatian: • Uzmite novu iglu i položite je uz brizgalicu.
English: Cardiac disorders palpitations*
Croatian: Srčani poremećaji palpitacije*
English: The MAH should collect data on clinical hard endpoints (bone, soft tissue calcifications and renal function), together with data on hypercalciuria and quality of life.
Croatian: Nositelj odobrenja mora prikupljati podatke na klinički čvrstim mjerama ishoda (kost, kalcifikacije mekih tkiva i bubrežna funkcija), zajedno s podacima o hiperkalciuriji i kvaliteti života.
English: Sharing your pen or pen needles may give yourself or others a serious infection.
Croatian: Dijeljenjem brizgalice ili igala možete dobiti ozbiljnu infekciju ili zaraziti druge osobe.
English: • nausea and vomiting*
Croatian: • mučnina i povraćanje*
English: Greater than 2.25 mmol/L and below the upper limit of normal (2.55 mmol/L)*
Croatian: Više od 2,25 mmol/l i ispod gornje granice normale (2,55 mmol/l)*
English: • When your sharps disposal container is two thirds full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container.
Croatian: • Kada je spremnik za oštre predmete dvije trećine napunjen, postupite prema važećim smjernicama za pravilno zbrinjavanje spremnika za oštre predmete.
English: Hypercalcaemia and hypocalcaemia were commonly encountered during the dose titration period.
Croatian: Hiperkalcemija i hipokalcemija bile su česte tijekom razdoblja titracije doze.
English: Combined use of Natpar and cardiac glycosides (e.g., digoxin or digitoxin) may predispose patients to digitalis toxicity if hypercalcaemia develops.
Croatian: . Kombinirana uporaba lijeka Natpar i kardioaktivnih glikozida (npr. digoksina ili digitoksina) može predisponirati bolesnike za toksičnost digitalisa ako dođe do razvoja hiperkalcemije.
English: Do not blow on it or fan it with your hand.
Croatian: Nemojte ga sušiti puhanjem ili mahanjem ruke iznad tog područja.
English: Natpar is a protein that is not metabolised by and does not inhibit hepatic microsomal drug-metabolising enzymes (e.g., cytochrome P450 isoenzymes).
Croatian: Natpar je protein koji se ne metabolizira jetrenim mikrosomalnim enzimima koji metaboliziraju lijekove (npr. izoenzimi citokroma P450) niti ih inhibira.
English: If the needle is not pointing straight up or the cartridge is screwed down too quickly during this step, medicine may leak from your pen.
Croatian: Ako tijekom ovog koraka igla nije usmjerena ravno prema gore ili ako ste prebrzo zakrenuli uložak, iz brizgalice može curiti lijek.
English: If pre-dose serum calcium is below 1.87 mmol/L or above 2.55 mmol/L, this measurement should be repeated the following day.
Croatian: Ako je prije primjene doze kalcij u serumu ispod 1,87 mmol/l ili iznad 2,55 mmol/l, mjerenje treba ponoviti sljedeći dan.
English: The pharmacokinetics of Natpar following subcutaneous administration in the thigh of hypoparathyroidism subjects was consistent with that observed in healthy post-menopausal women who received parathyroid hormone in the thigh and abdomen.
Croatian: Farmakokinetika lijeka Natpar nakon supkutane primjene u bedro ispitanika s hipoparatiroidizmom bila je u skladu s onom opaženom u zdravih žena u postmenopauzi koje su primile paratiroidni hormon u bedro i abdomen.
English: • pain in your muscles
Croatian: • bol u mišićima
English: Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see section 5.3).
Croatian: Istraživanja na životinjama ne ukazuju na izravan ili neizravan štetan učinak na reprodukciju (vidjeti dio 5.3).
English: Measurements of pre- and post-dose serum calcium should be repeated and confirmed to be within an acceptable range before titration to a higher dose of Natpar is considered.
Croatian: Mjerenja kalcija u serumu prije i nakon doze treba ponoviti i potvrditi da se vrijednosti nalaze u prihvatljivom rasponu prije razmatranja titriranja na višu dozu lijeka Natpar.
English: Less than or equal to 2.25 mmol/L and above 2 mmol/L
Croatian: Manje ili jednako 2,25 mmol/l i iznad 2 mmol/l
English: How do I throw away my pen?
Croatian: Kako ću baciti brizgalicu?
English: This means that further evidence on this medicinal product is awaited.
Croatian: To znači da se očekuju dodatni podaci o ovom lijeku.
English: Natpar is indicated as adjunctive treatment of adult patients with chronic hypoparathyroidism who cannot be adequately controlled with standard therapy alone.
Croatian: Natpar je indiciran kao pomoćna terapija u odraslih bolesnika s kroničnim hipoparatiroidizmom koji ne mogu biti prikladno liječeni samo standardnom terapijom.
English: 1 • If you just completed “New Pen Setup & Mixing” (Section B), go to Step 8 below.
Croatian: 1. • Ako ste upravo završili „Pripremu nove brizgalice i miješanje lijeka“ (dio B), prijeđite na 8. korak opisan nešto dalje u tekstu.
English: If severe hypercalcaemia (>3.0 mmol/L or above upper limit of normal with symptoms) develops, hydration and temporarily stopping Natpar, calcium and active vitamin D should be considered until serum calcium returns to the normal range.
Croatian: Ako se razvije teška hiperkalcemija (>3,0 mmol/l ili iznad gornje granice normale sa simptomima), treba razmotriti primjenu hidracije i privremeni prekid primjene lijeka Natpar, kalcija i aktivnog vitamina D dok se kalcij u serumu ne vrati u normalan raspon.
English: • Confirm serum magnesium is within the reference range.
Croatian: • Provjerite je li magnezij u serumu unutar referentnih vrijednosti.
English: Natpar pen 25 Natpar pen 50 Natpar pen 75 Natpar pen 100
Croatian: Natpar brizgalica 25 Natpar brizgalica 50 Natpar brizgalica 75 Natpar brizgalica 100
English: Treatment with Natpar increases serum calcium concentration in hypoparathyroidism patients, and this increase occurs in a dose-related manner.
Croatian: Liječenje lijekom Natpar povećava koncentraciju kalcija u serumu u bolesnika s hipoparatiroidizmom, a to povećanje nastupa na način povezan s dozom.
English: Instructions for use” in this leaflet before you use the pen.
Croatian: Upute za uporabu” u ovoj uputi prije korištenja brizgalice.
English: There are no data on the effects of Natpar on human fertility.
Croatian: Nema podataka o učincima lijeka Natpar na plodnost u ljudi.
English: In patients using active vitamin D, decrease the dose of active vitamin D by 50%, if pre-dose serum calcium is above 1.87 mmol/L.
Croatian: Ako bolesnici koriste aktivni vitamin D, smanjite dozu aktivnog vitamina D za 50%, ako je kalcij u serumu prije primjene doze iznad 1,87 mmol/l.
English: Important: It is normal to see 1 or 2 drops of medicine leaking out of the skin or from the needle tip after this step.
Croatian: Važno: Poslije ovog koraka normalno je primijetiti da iz kože ili s vrha igle iscure 1 ili 2 kapi lijeka.
English: Important: Dispose of your pen on the “Discard On” date even if you have medicine left in your pen.
Croatian: Važno: Brizgalicu bacite na datum naveden pored „Baciti“ čak i ako je u brizgalici ostalo još lijeka.
English: Nervous system disorders headache* hypoaesthesia paraesthesia somnolence*
Croatian: Poremećaji živčanog sustava glavobolja* hipoestezija parestezija somnolencija*
English: Natpar is contraindicated in patients: - with hypersensitivity to the active substance or to any of the excipients listed in section 6.1 - who are receiving or who have previously received radiation therapy to the skeleton - with skeletal malignancies or bone metastases - who are at increased baseline risk for osteosarcoma such as patients with Paget's disease of bone or hereditary disorders - with unexplained elevations of bone-specific alkaline phosphatase - with pseudohypoparathyroidism.
Croatian: Natpar je kontraindiciran u bolesnika: - koji su preosjetljivi na djelatnu tvar ili neku od pomoćnih tvari navedenih u dijelu 6.1 - koji primaju ili su prije primali radijacijsku terapiju kostiju - koji imaju maligna oboljenja kostiju ili metastaze na kostima - kod kojih postoji povećan početni rizik od osteosarkoma, kao što su bolesnici s Pagetovom bolešću kostiju ili nasljednim poremećajima - kod kojih postoje neobjašnjiva povećanja alkalne fosfataze specifične za kosti - kod kojih postoji pseudohipoparatiroidizam.
English: This confirms that your pen has not been primed yet.
Croatian: To je znak da brizgalica još nije napunjena.
English: Hypocalcaemia may be minimised by following the recommended dosing, the monitoring information, and asking patients about any symptoms of hypocalcaemia (see sections 4.2 and 4.8).
Croatian: Hipokalcemija može biti minimizirana praćenjem preporučenog doziranja, informacija o nadziranju bolesnika, te postavljanjem pitanja bolesnicima o bilo kojim simptomima hipokalcemije (vidjeti dijelove 4.2 i 4.8).
English: A minimal amount of Natpar is excreted in the milk of lactating rats.
Croatian: Minimalna količina lijeka Natpar izlučivala se u mlijeko ženki štakora za vrijeme laktacije.
English: Avoid areas with scars, bruises, redness, or moles.
Croatian: Izbjegavajte područja s ožiljcima, modricama, crvenilom kože ili madežima.
English: Patients must be trained on the proper injection techniques by the prescriber or nurse, in particular during initial use.
Croatian: Liječnik koji propisuje lijek ili medicinska sestra moraju obučiti bolesnike u pogledu pravilnih tehnika davanja injekcija, posebno na početku uporabe.
English: Natpar has no effect on your being able to drive or use machines.
Croatian: Natpar nema nikakvih učinaka na Vašu sposobnost upravljanja vozilima ili rada sa strojevima.
English: Hypercalcaemia may be minimised by following the recommended dosing, the monitoring information, and asking patients about any symptoms of hypercalcaemia.
Croatian: Hiperkalcemija može biti minimizirana praćenjem preporučenog doziranja, informacija o nadziranju bolesnika, te postavljanjem pitanja bolesnicima o bilo kojim simptomima hiperkalcemije.
English: 10 • While holding the pen with the needle cap pointing straight up, press the blue button on a flat surface until you hear or feel a ‘hard' click (See Figure K) and the blue button stays in.
Croatian: 10. • Dok držite brizgalicu s kapicom igle usmjerenom ravno prema gore, pritisnite plavi gumb o ravnu površinu dok ne čujete ili ne osjetite „čvrsti“ klik (pogledajte sliku K) i plavi gumb ne ostane uvučen.
English: Important: Carefully read Step 10 through Step 14 before injecting.
Croatian: Važno: Prije injiciranja lijeka pažljivo pročitajte upute od 10. do 14. koraka.
English: 17 Discard your used needles:
Croatian: Bacite iskorištene igle:
English: What if I see air bubbles floating in the medicine or the medicine appears foamy after mixing?
Croatian: Što ako vidim mjehuriće zraka u lijeku ili poslije miješanja u lijeku ima pjene?
English: Do not place your pen under water.
Croatian: Nemojte stavljati brizgalicu pod vodu.
English: E. Frequently Asked Questions
Croatian: Česta pitanja
English: Natpar 100 micrograms/dose Blue pen label.
Croatian: Natpar 100 mikrograma/doza Plava naljepnica na brizgalici.
English: • Continue to point the needle straight down.
Croatian: • Nastavite držati iglu usmjerenu ravno prema dolje.
English: Natpar is suitable for patient self-administration.
Croatian: Natpar je pogodan za samoprimjenu od strane bolesnika.
English: Your pen is to be used daily for 14 days and should be thrown away (discarded) 14 days after mixing, even if medicine remains in the pen.
Croatian: Brizgalicu koju ste svakodnevno upotrebljavali tijekom 14 dana morate baciti nakon što je prošlo 14 dana od miješanja lijeka, čak i ako je u njoj ostalo još lijeka.
English: Abrupt interruption or discontinuation of Natpar can result in severe hypocalcaemia.
Croatian: Nagli privremen ili trajan prekid primjene lijeka Natpar može rezultirati teškom hipokalcemijom.