FrancophonIA/ELRC3.0 huggingface dataset:
English: • get left upper belly (abdominal) pain, pain below the left rib cage or at the tip of your left shoulder (these may be symptoms of an enlarged spleen (splenomegaly), or possibly rupture of the spleen).
Croatian: • Vam se pojavi bol u lijevom gornjem dijelu trbuha (abdomena), bol ispod lijevog rebrenog luka ili u vrhu lijevog ramena (to mogu biti simptomi povećane slezene (splenomegalije) ili možda i puknuća (rupture) slezene),
English: The subcutaneous route is preferred in most cases.
Croatian: U većini se slučajeva prednost daje supkutanom putu primjene.
English: The long-term safety of administration of Grastofil at doses above 2.4 MU/kg/day (24 micrograms/kg/day) in patients with SCN has not been established.
Croatian: Sigurnost dugotrajne primjene Grastofila u dozama većim od 2,4 MU/kg/dan (24 mikrograma/kg/dan) u bolesnika s teškom kroničnom neutropenijom nije utvrđena.
English: Data from clinical studies in paediatric patients indicate that the safety and efficacy of filgrastim are similar in both adults, children and adolescents receiving cytotoxic chemotherapy suggesting no agerelated differences in the pharmacokinetics of filgrastim.
Croatian: Podaci iz kliničkih ispitivanja filgrastima u pedijatrijskih bolesnika pokazuju da su sigurnost i djelotvornost filgrastima u djece i adolescenata koji primaju citotoksičnu kemoterapiju slične onima u odraslih, što ukazuje na to da nema razlike u farmakokinetici filgrastima povezane s dobi.
English: Cases of capillary leak syndrome have been reported with granulocyte colony-stimulating factor use.
Croatian: Slučajevi stanja povećane kapilarne propusnosti zabilježeni su uz primjenu čimbenika poticanja granulocitnih kolonija.
English: • inflammation of the blood vessels in the skin (cutaneous vasculitis)
Croatian: • upala krvnih žila u koži (kožni vaskulitis)
English: The usual starting dose is between 0.1 million units (1 micrograms) and 0.4 million units (4 micrograms) per kilogram bodyweight each day.
Croatian: Uobičajena početna doza je između 0,1 milijuna jedinica (1 mikrograma) i 0,4 milijuna jedinica (4 mikrograma) po kilogramu tjelesne težine dnevno.
English: Store in a refrigerator (2 °C - 8 °C).
Croatian: Čuvati u hladnjaku (2 °C-8 °C).
English: In patients with known bone marrow-infiltrating infections or malignancy, consider appropriate therapy for treatment of the underlying condition in addition to administration of filgrastim for treatment of neutropenia.
Croatian: U bolesnika s poznatim infekcijama ili zloćudnom bolešću koje infiltriraju koštanu srž, razmotrite odgovarajuće liječenje tog osnovnog stanja uz primjenu filgrastima za liječenje neutropenije.
English: The recommended dose of Grastofil for PBPC mobilisation after myelosuppressive chemotherapy is 0.5 MU/kg/day (5 micrograms/kg/day) from the first day after completion of chemotherapy until the expected neutrophil nadir is passed and the neutrophil count has recovered to the normal range.
Croatian: Preporučena doza Grastofila za mobilizaciju progenitorskih stanica periferne krvi nakon mijelosupresivne kemoterapije iznosi 0,5 MU/kg/dan (5 mikrograma/kg/dan) od prvog dana nakon završetka kemoterapije do očekivanog najnižeg pada broja neutrofila te njihovog oporavka do normalnog raspona vrijednosti.
English: If you are donating stem cells for yourself, the usual dose is 0.5 million units (5 micrograms) to 1 million units (10 micrograms) per kilogram bodyweight each day.
Croatian: Ako darujete matične stanice samom sebi, uobičajena doza je 0,5 milijuna jedinica (5 mikrograma) do 1 milijun jedinica (10 mikrograma) po kilogramu tjelesne težine svaki dan.
English: Dilution to a final concentration less than 0.2 MU (2 µg) per mL is not recommended at any time.
Croatian: Nikako se ne preporučuje razrijediti do konačne koncentracije manje od 0,2 MU (2 µg) po ml.
English: Treatment with filgrastim significantly reduces the duration of febrile neutropenia, antibiotic use and hospitalisation after induction chemotherapy for acute myelogenous leukaemia or myeloablative therapy followed by bone marrow transplantation.
Croatian: Liječenje filgrastimom značajno smanjuje trajanje febrilne neutropenije, primjenu antibiotika i hospitalizaciju nakon indukcijske kemoterapije zbog akutne mijelogene leukemije ili mijeloablativnog liječenja nakon kojeg slijedi transplantacija koštane srži.
English: Transient thrombocytopenia (platelets < 100 x 10
Croatian: Prolazna trombocitopenija (trombociti < 100 x 10
English: Glacial acetic acid, sodium hydroxide, sorbitol (E420), polysorbate 80, and water for injections.
Croatian: Ledena acetatna kiselina, natrijev hidroksid, sorbitol (E420), polisorbat 80 i voda za injekcije.
English: • sickle cell anaemia, as filgrastim can cause sickle cell crisis.
Croatian: • anemiju srpastih stanica, jer filgrastim može uzrokovati krizu srpastih stanica.
English: Idiopathic or cyclic neutropenia: the recommended starting dose is 0.5 MU/kg/day (5 micrograms/kg/day) as a single dose or in divided doses.
Croatian: Idiopatska ili ciklička neutropenija: Preporučena početna doza je 0,5 MU/kg/dan (5 mikrograma/kg/dan) primijenjena u jednoj ili više doza.
English: • to increase the number of white blood cells if you suffer from severe chronic neutropenia to help prevent infections;
Croatian: • za povećanje broja bijelih krvnih stanica ako patite od teške kronične neutropenije, radi sprječavanja infekcija,
English: The usual starting dose is between 0.5 million units (5 micrograms) and 1.2 million units (12 micrograms) per kilogram bodyweight each day in a single or divided dose.
Croatian: Uobičajena početna doza je između 0,5 milijuna jedinica (5 mikrograma) i 1,2 milijuna jedinica (12 mikrograma) po kilogramu tjelesne težine svaki dan u jednoj ili više doza.
English: There have been reports of GvHD and fatalities in patients after allogeneic bone marrow transplantation (see section Description of selected adverse reactions)
Croatian: Zabilježeni su slučajevi GvHD-a i smrtni ishodi u bolesnika nakon transplantacije alogene koštane srži (vidjeti dio: Opis odabranih nuspojava)
English: Initial dose adjustment to alternate day dosing with 30 MU/day (300 micrograms/day) is recommended.
Croatian: Preporučuje se početna prilagodba doze na 30 MU/dan (300 mikrograma/dan) primijenjena svaki drugi dan.
English: Congenital neutropenia: the recommended starting dose is 1.2 MU/kg/day (12 micrograms/kg/day) as a single dose or in divided doses.
Croatian: Kongenitalna neutropenija: preporučena početna doza je 1,2 MU/kg/dan (12 mikrograma/kg/dan) primijenjena u jednoj ili više doza.
English: Leukocytosis White blood cell counts of 100 x 10
Croatian: Broj bijelih krvnih stanica od 100 x 10
English: • inflammation of the lungs (interstitial lung disease)
Croatian: • upala pluća (intersticijska bolest pluća)
English: Each syringe of 0.5 mL solution contains 48 MU (480 micrograms) of filgrastim (960 micrograms/mL).
Croatian: Jedna štrcaljka s 0,5 ml otopine sadrži 48 MU (480 mikrograma) filgrastima (960 mikrograma/ml).
English: The first dose of Grastofil should be administered at least 24 hours after cytotoxic chemotherapy.
Croatian: Prva doza Grastofila treba se primijeniti najmanje 24 sata nakon citotoksične kemoterapije.
English: Following termination of filgrastim therapy, circulating neutrophil counts decrease by 50% within 1 to 2 days, and to normal levels within 1 to 7 days.
Croatian: Nakon prestanka liječenja filgrastimom, broj cirkulirajućih neutrofila smanji se za 50% u roku od 1 do 2 dana te na normalne vrijednosti unutar 1 do 7 dana.
English: • decrease of platelets which reduces the ability of blood to clot (thrombocytopenia)
Croatian: • smanjenje broja trombocita, što smanjuje sposobnost zgrušavanja krvi (trombocitopenija)
English: Grastofil and bone marrow transplantation
Croatian: Grastofil i presađivanje koštane srži
English: • lack of absorption of oxygen in the lung (hypoxia)
Croatian: • smanjena apsorpcija kisika u plućima (hipoksija)
English: • bleeding from the lung (pulmonary haemorrhage)
Croatian: • krvarenje iz pluća (plućna hemoragija)
English: For the mobilisation of peripheral blood progenitor cells (PBPC) in patients undergoing myelosuppressive or myeloablative therapy followed by autologous PBPC transplantation
Croatian: Za mobilizaciju progenitorskih stanica periferne krvi u bolesnika u tijeku mijelosupresivne i mijeloablativne terapije nakon kojeg slijedi transplantacija autolognih progenitorskih stanica periferne krvi
English: The first dose of Grastofil should be administered at least 24 hours after cytotoxic chemotherapy and at least 24 hours after bone marrow infusion.
Croatian: Prvu dozu Grastofila treba dati najmanje 24 sata nakon citotoksične kemoterapije i najmanje 24 sata nakon infuzije koštane srži.
English: The recommended starting dose of Grastofil is 1.0 MU/kg/day (10 micrograms/kg/day).
Croatian: Preporučena početna doza Grastofila je 1,0 MU/kg/dan (10 mikrograma/kg/dan).
English: • upper respiratory tract infection
Croatian: • infekcija gornjih dišnih putova
English: • to increase the number of white blood cells after treatment with chemotherapy to help prevent infections;
Croatian: • za povećanje broja bijelih krvnih stanica nakon liječenja kemoterapijom radi sprječavanja infekcija,
English: There were no differences in the safety profiles for paediatric patients treated for SCN.
Croatian: Nije bilo razlike u sigurnosnim profilima u pedijatrijskih bolesnika liječenih zbog teške kronične neutropenije.
English: You may change the injection site if you notice the area is red or sore.
Croatian: Ako primjetite da je mjesto injekcije crveno ili bolno, možete ga promijeniti.
English: The usual dose is 0.5 million units (5 micrograms) per kilogram of bodyweight each day.
Croatian: Uobičajena doza je 0,5 milijuna jedinica (5 mikrograma) po kilogramu tjelesne težine svakog dana.
English: The usual starting dose is 1 million units (10 micrograms) per kilogram of bodyweight each day given as an infusion.
Croatian: Uobičajena početna doza je 1 milijun jedinica (10 mikrograma) po kilogramu tjelesne težine svaki dan primijenjena u infuziji.
English: Special warning and precautions associated with co-morbidities
Croatian: Posebna upozorenja i mjere opreza u vezi s istodobno prisutnim bolestima
English: Grastofil for PBPC mobilisation when used alone Grastofil may be given as a 24 hour subcutaneous continuous infusion or subcutaneous injection.
Croatian: Kad se za mobilizaciju progenitorskih stanica periferne krvi primjenjuje samo Grastofil Grastofil se može primijeniti putem 24-satne supkutane kontinuirane infuzije ili supkutane injekcije.
English: Regular monitoring of platelet count and haematocrit is recommended.
Croatian: Preporučuje se redovito mjerenje broja trombocita i hematokrita.
English: Premature discontinuation of Grastofil therapy, prior to the time of the expected neutrophil nadir, is not recommended.
Croatian: Ne preporučuje se preuranjeni prekid terapije Grastofilom, prije očekivanog pada broja neutrofila na najnižu vrijednost.
English: It is advisable to wait and see how you feel after receiving Grastofil and before driving or operating machinery.
Croatian: Prije upravljanja vozilima ili rukovanja strojevima preporučljivo je pričekati da vidite kako ćete se osjećati nakon što primite Grastofil.
English: The needle cover of the pre-filled syringe contains dry natural rubber (a derivative of latex), which may cause allergic reactions.
Croatian: Pokrov igle na napunjenoj štrcaljki sadrži suhu prirodnu gumu (derivat lateksa), koja može uzrokovati alergijske reakcije.
English: The needle cover of the pre-filled syringe contains dry natural rubber (a derivative of latex) which may cause an allergic reaction.
Croatian: Pokrov igle na napunjenoj štrcaljki sadrži suhu prirodnu gumu (derivat lateksa), koja može izazvati alergijsku reakciju.
English: Special precautions in normal donors undergoing peripheral blood progenitor cell mobilisation
Croatian: Posebne mjere opreza u zdravih darivatelja u kojih se provodi mobilizacija progenitorskih stanica periferne krvi
English: Rare (≥ 1/10,000 to <
Croatian: Rijetko (≥1/10 000 i
English: The recommended dose of Grastofil is 0.5 MU/kg/day (5 micrograms/kg/day).
Croatian: Preporučena doza Grastofila je 0,5 MU/kg/dan (5 mikrograma/kg/dan).
English: European Retrospective Study (2004)
Croatian: Europsko retrospektivno ispitivanje b
English: Filgrastim has minor influence on the ability to drive and use machines.
Croatian: Filgrastim malo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: • you have any of the following or a combination of the following side effects: o swelling or puffiness, which may be associated with passing water less frequently, difficulty breathing, abdominal swelling and feeling of fullness, and a general feeling of tiredness.
Croatian: • imate jednu ili više od sljedećih nuspojava: o oticanje ili podbuhlost, možebitno popraćeno rjeđom potrebom za mokrenjem, poteškoće s disanjem, oticanje u području abdomena i osjećaj sitosti uz opći osjećaj umora.
English: Data from clinical studies in paediatric patients indicate that the safety and efficacy of filgrastim are similar in both adults, children and adolescents receiving cytotoxic chemotherapy.
Croatian: Podaci iz kliničkih ispitivanja u pedijatrijskih bolesnika pokazuju da su sigurnost i djelotvornost filgrastima u djece i adolescenata koji primaju citotoksičnu kemoterapiju slične onima u odraslih.
English: 9/L during the treatment period, the dose of Grastofil should be reescalated according to the above steps ANC = absolute neutrophil count
Croatian: 9/l tijekom razdoblja liječenja, dozu Grastofila potrebno je ponovno povisiti sukladno gore opisanim koracima.
English: Telephone +39/02-89.421721
Croatian: CRINOS S.p.A. Tel: +39/02-89.421721
English: Each syringe of 0.5 mL solution contains 30 MU (300 micrograms) of filgrastim (600 micrograms/mL).
Croatian: Jedna štrcaljka s 0,5 ml otopine sadrži 30 MU (300 mikrograma) filgrastima (600 mikrograma/ml).
English: Permanently discontinue filgrastim in patients with clinically significant hypersensitivity.
Croatian: Liječenje filgrastimom mora se trajno prekinuti u bolesnika koji razviju klinički značajnu preosjetljivost.
English: Grastofil and neutropenia (low number of a type of white blood cells) associated with chemotherapy
Croatian: Grastofil i neutropenija (nizak broj podvrste bijelih krvnih stanica) uzrokovana kemoterapijom
English: Hypersensitivity-type reactions including anaphylaxis, rash, urticaria, angioedema, dyspnoea and hypotension occurring on initial or subsequent treatment have been reported in clinical studies and in post-marketing experience.
Croatian: Pojava reakcija preosjetljivosti uključujući anafilaksiju, osip, urtikariju, angioedem, dispneju i hipotenziju zabilježena je na početku i kasnije tijekom liječenja bolesnika koji su primali filgrastim.
English: Type I glass pre-filled syringe with permanently attached stainless steel needle in the tip and 1/40 printed markings for graduations from 0.1 mL to 1 mL on the barrel.
Croatian: I s neodvojivom iglom od nehrđajućeg čelika na vrhu i gradacijskom skalom s 1/40 otisnutim oznakama od 0,1 ml do 1 ml na tijelu štrcaljke.
English: Once the neutrophil nadir has been passed, the daily dose of Grastofil should be titrated against the neutrophil response as follows:
Croatian: Nakon prestanka pada broja neutrofila na najnižu vrijednost, dnevnu dozu Grastofila potrebno je prilagoditi odgovoru neutrofila na sljedeći način:
English: The recommended dose of Grastofil for PBPC mobilisation when used alone is 1.0 MU/kg/day (10 micrograms/kg/day) for 5-7 consecutive days.
Croatian: Preporučena doza Grastofila za mobilizaciju progenitorskih stanica periferne krvi kad se primjenjuje sam iznosi 1,0 MU/kg/dan (10 mikrograma/kg/dan) tijekom 5 do 7 uzastopnih dana.
English: The duration of fever was not reduced in patients undergoing myeloablative therapy followed by bone marrow transplantation.
Croatian: Trajanje vrućice nije bilo smanjeno u bolesnika na mijeloablativnom liječenju prije transplantacije koštane srži.
English: Grastofil should be diluted in 20 mL of 5% glucose solution (see section 6.6).
Croatian: Grastofil se treba razrijediti u 20 ml 5%-tne otopine glukoze (vidjeti dio 6.6).
English: Prior exposure to cytotoxic medicinal products
Croatian: Prethodno izlaganje citotoksičnim lijekovima
English: Telephone +385/1.3764.111
Croatian: STADA d.o.o Tel: +385/1.3764.111
English: Special precautions in recipients of allogeneic PBPC mobilised with filgrastim Current data indicate that immunological interactions between the allogeneic PBPC graft and the recipient may be associated with an increased risk of acute and chronic GvHD when compared with bone marrow transplantation.
Croatian: Sadašnji podaci pokazuju da imunološke interakcije između alogenog presatka progenitorskih stanica periferne krvi i primatelja mogu biti povezane s povećanim rizikom od akutnog i kroničnog GvHD-a u usporedbi s transplantacijom koštane srži.
English: Each pre-filled syringe contains 48 MU (480 μg) filgrastim in 0.5 mL solution.
Croatian: Jedna napunjena štrcaljka sadrži 48 MU (480 μg) filgrastima u 0,5 ml otopine.
English: 9/L prior to leukapheresis; in general apheresis should not be performed if platelets are
Croatian: 9/l prije leukafereze; općenito aferezu se ne smije provoditi ako je broj trombocita < 75 x 10
English: • soreness and swelling of the digestive tract lining which runs from the mouth to the anus
Croatian: • bolnost i oticanje sluznice probavnog trakta koja se proteže od usta do čmara (upala sluznice)
English: • inflammation of the lung (bronchitis)
Croatian: • upala u plućima (bronhitis)
English: Pseudogout (chondrocalcinosis pyrophosphate) has been reported in cancer patients treated with filgrastim.
Croatian: Pseudogiht (pirofosfatna hondrokalcinoza) U onkoloških bolesnika liječenih filgrastimom zabilježen je pseudogiht (pirofosfatna hondrokalcinoza).
English: Physicians should use caution when prescribing filgrastim in patients with sickle cell trait or sickle cell disease.
Croatian: Liječnici trebaju s oprezom propisivati filgrastim u bolesnika s nasljednim obilježjem srpastih stanica ili anemijom srpastih stanica.
English: Your doctor may then test your blood to see how well the treatment is working and how long it should last.
Croatian: Vaš liječnik Vam može napraviti krvne pretrage kako bi ocijenio djelotvornost liječenja te odlučio o potrebnoj duljini trajanja liječenja.
English: Each pre-filled syringe contains 0.5 mL of solution.
Croatian: Svaka napunjena štrcaljka sadrži 0,5 ml otopine.
English: • changes in blood chemistry
Croatian: • promjene u biokemijskim laboratorijskim nalazima
English: You will normally receive your first dose of Grastofil at least 24 hours after your chemotherapy and at least 24 hours after receiving your bone marrow transplant.
Croatian: Prvu dozu Grastofila u pravilu ćete primiti najmanje 24 sata nakon kemoterapije i najmanje 24 sata nakon primanja presatka koštane srži.
English: Daily dosing with Grastofil should continue until the expected neutrophil nadir is passed and the neutrophil count has recovered to the normal range.
Croatian: Svakodnevnu primjenu Grastofila potrebno je nastaviti sve do prestanka očekivanog najnižeg pada broja neutrofila i njihovog porasta do normalnog raspona vrijednosti.
English: For PBPC mobilisation in normal donors, Grastofil should be administered at 1.0 MU/kg/day (10 micrograms/kg/day) for 4 - 5 consecutive days.
Croatian: Za mobilizaciju progenitorskih stanica periferne krvi u zdravih darivatelja, Grastofil je potrebno primijeniti u dozi od 1,0 MU/kg/dan (10 mikrograma/kg/dan) tijekom 4-5 uzastopnih dana.
English: Each pre-filled syringe contains 30 MU (300 μg) filgrastim in 0.5 mL solution.
Croatian: Jedna napunjena štrcaljka sadrži 30 MU (300 μg) filgrastima u 0,5 ml otopine.
English: > 5.0 x 10
Croatian: 9/l na > 5,0 x 10
English: What Grastofil is used for
Croatian: Za što se Grastofil koristi
English: Paediatric patients in the SCN and cancer settings
Croatian: Pedijatrijski bolesnici s teškom kroničnom neutropenijom i karcinomom
English: Each mL of solution contains 96 million units (MU) (equivalent to 960 micrograms [μg]) of filgrastim.
Croatian: Jedan ml otopine sadrži 96 milijuna jedinica (MU) (što odgovara 960 mikrograma [µg]) filgrastima.
English: Your doctor will monitor your blood to determine the best time to collect the stem cells.
Croatian: Vaš će liječnik redovito raditi krvne pretrage kako bi se odredilo najbolje vrijeme za prikupljanje matičnih stanica.
English: For example, if you weigh 60 kilograms your daily dose will be 30 million units (300 micrograms).
Croatian: Na primjer, ako je Vaša tjelesna težina 60 kilograma, Vaša dnevna doza iznosit će 30 milijuna jedinica
English: Cases of decreased bone density and osteoporosis have been reported in paediatric patients with severe chronic neutropenia receiving chronic treatment with filgrastim.
Croatian: Pedijatrijski bolesnici s teškom kroničnom neutropenijom Slučajevi smanjene gustoće kostiju i osteoporoze zabilježeni su u pedijatrijskih bolesnika s teškom kroničnom neutropenijom koji se dugotrajno liječe filgrastimom.
English: Filgrastim should not be administered to patients with severe congenital neutropenia who develop leukaemia or have evidence of leukaemic evolution.
Croatian: Posebne mjere opreza u bolesnika s teškom kroničnom neutropenijom Filgrastim se ne smije primjenjivati u bolesnika s teškom kongenitalnom neutropenijom koji imaju leukemiju ili u kojih postoji dokaz razvoja leukemije.
English: How to use Grastofil
Croatian: Kako primjenjivati Grastofil
English: Capillary leak syndrome, which can be life-threatening if treatment is delayed, has been reported after granulocyte colony-stimulating factor administration, and is characterised by hypotension, hypoalbuminaemia, oedema and hemoconcentration.
Croatian: Nakon primjene čimbenika poticanja granulocitnih kolonija (G-CSF) zabilježena je pojava stanja povećane kapilarne propusnosti („sindrom kapilarnog curenja“), koje u slučaju nepravodobnog liječenja može biti opasno po život, a karakteriziraju ga hipotenzija, hipoalbuminemija, edem i hemokoncentracija.
English: Each mL of solution contains 60 million units (MU) (equivalent to 600 micrograms [μg]) of filgrastim.
Croatian: Jedan ml otopine sadrži 60 milijuna jedinica (MU) (što odgovara 600 mikrograma [μg]) filgrastima.
English: How to store Grastofil
Croatian: Kako čuvati Grastofil
English: Complete blood cell counts with differential and platelet counts and an evaluation of bone marrow morphology and karyotype should be performed prior to treatment.
Croatian: Prije liječenja potrebno je napraviti kompletnu krvnu sliku s diferencijalnom krvnom slikom i brojem trombocita te procjenu morfologije i kariotipa koštane srži.
English: • to increase the number of white blood cells after a bone marrow transplant to help prevent infections;
Croatian: • za povećanje broja bijelih krvnih stanica nakon presađivanja koštane srži radi sprječavanja infekcija,
English: Suomi/Finland
Croatian: Suomi
English: • a new pre-filled syringe of Grastofil; and
Croatian: • nova napunjena štrcaljka Grastofila.
English: Urinalysis monitoring is recommended.
Croatian: Preporučuje se praćenje analizom mokraće.
English: How Grastofil is given
Croatian: Kako se Grastofil primjenjuje
English: Effect of chemotherapy on erythrocytes and thrombocytes Treatment with filgrastim alone does not preclude thrombocytopenia and anaemia due to myelosuppressive chemotherapy.
Croatian: Liječenje samo filgrastimom ne isključuje trombocitopeniju i anemiju zbog mijelosupresivne kemoterapije.
English: • think you may be pregnant, or
Croatian: Važno je da kažete svom liječniku: ako ste trudni ili dojite mislite da biste mogli biti trudni ili planirate imati dijete
English: Monitoring of bone density may be indicated in patients with underlying osteoporotic bone diseases who undergo continuous therapy with filgrastim for more than 6 months.
Croatian: U bolesnika s postojećom osteoporozom koji su na kontinuiranoj terapiji filgrastimom dulje od 6 mjeseci indicirano je mjerenje gustoće kostiju.