FrancophonIA/ELRC3.0 huggingface dataset:
English: Imatinib was not considered genotoxic when tested in an in vitro bacterial cell assay (Ames test), an in vitro mammalian cell assay (mouse lymphoma) and an in vivo rat micronucleus test.
Danish: Imatinib ansås ikke som værende genotoksisk i in vitro bakteriecelleundersøgelse (Ames-test), i in vitro pattedyrscelleundersøgelse (muselymfom) samt i in vivo rottemikronukleusundersøgelse.
English: Patients with renal impairment should be given the minimum starting dose.
Danish: Der bør anvendes mindste startdosis til patienter med nedsat nyrefunktion.
English: Arrhythmia, atrial fibrillation, cardiac arrest, myocardial infarction, angina pectoris, pericardial effusion
Danish: Arytmi, atrieflimren, hjertestop, myokardieinfarkt, angina pectoris, perikardiel effusion
English: Pruritus, face oedema, dry skin, erythema, alopecia, night sweats, photosensitivity
Danish: Pruritus, ansigtsødem, tør hud, erythem, alopeci, natlig svedtendens,
English: Pleuritic pain, pulmonary fibrosis, pulmonary hypertension, pulmonary haemorrhage
Danish: Pleuralgi, lungefibrose, pulmonal hypertension, pulmonal blødning
English: Hepatic function should be carefully monitored in circumstances where imatinib is combined with chemotherapy regimens also known to be associated with hepatic dysfunction (see section 4.5 and 4.8).
Danish: Nøje monitorering af leverfunktionen skal udføres i tilfælde, hvor imatinib kombineres med kemoterapiregimer, som også vides at være forbundet med leverdysfunktion (se pkt.
English: Newly diagnosed Ph+ ALL: In a controlled study (ADE10) of imatinib versus chemotherapy induction in 55 newly diagnosed patients aged 55 years and over, imatinib used as single agent induced a significantly higher rate of complete haematological response than chemotherapy (96.3 % vs. 50 %; p = 0.0001).
Danish: Nydiagnostiseret Ph+ ALL: I et kontrolleret studie (ADE10) hvor imatinib blev sammenlignet med kemoterapi-induktion hos 55 nydiagnostiserede patienter i alderen 55 år og derover, gav imatinib brugt som monoterapi anledning til en signifikant højere ratio af hæmatologisk respons end kemoterapi (96,3 % vs. 50 %, p = 0,0001).
English: Dose increases from 340 mg/m daily to 570 mg/m daily (not to exceed the total dose of 800 mg) may be considered in the absence of severe adverse drug reaction and severe non-leukaemia-related neutropenia or thrombocytopenia in the following circumstances: disease progression (at any time); failure to achieve a satisfactory haematological response after at least 3 months of treatment; failure to achieve a cytogenetic response after 12 months of treatment; or loss of a previously achieved haematological and/or cytogenetic response.
Danish: Dosisøgning fra 340 mg/m² dagligt til 570 mg/m² dagligt (uden at overstige total dosis på 800 mg) kan overvejes ved fravær af alvorlige bivirkninger og svær ikke-leukæmirelateret neutropeni eller trombocytopeni ved følgende omstændigheder: sygdomsprogression (på ethvert tidspunkt); hvis der ikke er opnået tilfredsstillende hæmatologisk respons efter mindst 3 måneders behandling; hvis der ikke er opnået cytogenetisk respons efter 12 måneders behandling; eller ved tab af tidligere opnået hæmatologisk og/eller cytogenetisk respons.
English: 9/l, then resume treatment at 200 mg/m
Danish: 9l og genoptag behandling med 200 mg/m².
English: • Severe headache, weakness or paralysis of limbs or face, difficulty speaking, sudden loss of consciousness (signs of nervous system problems such as bleeding or swelling in skull/brain).
Danish: • Kraftig hovedpine, svækkelse eller lammelser af lemmer eller ansigt, talebesvær, pludseligt bevidsthedstab (tegn på problemer med nervesystemet såsom blødning eller hævelse i
English: Migraine, somnolence, syncope, peripheral neuropathy, memory impairment, sciatica, restless leg syndrome, tremor, cerebral haemorrhage
Danish: Migræne, døsighed, synkope, perifer neuropati, hukommelsessvigt, iskias, restless leg syndrome, tremor, hjerneblødning
English: 12 Gy in 8 fractions for all patients that are CNS1 and CNS2 at diagnosis 18 Gy in 10 fractions for patients that are CNS3 at diagnosis VCR (1.5 mg/m2/day, IV): days 1, 29
Danish: 18 Gy i 10 fraktioner for patienter, som er CNS3 ved diagnosticering VCR (1,5 mg/m²/dag, i.v.
English: Dosing in paediatric patients at 260 and 340 mg/m2/day achieved the same exposure, respectively, as doses of 400 mg and 600 mg in adult patients.
Danish: Doser på 260 og 340 mg/m²/dag til børn gav samme optagelse som doser på henholdsvis 400 mg og 600 mg til voksne.
English: Increased intracranial pressure, convulsions, optic neuritis
Danish: Øget interkranielt tryk, kramper, synsnervebetændelse
English: Ara-C 1,000 mg/m2/12 h i.v.
Danish: Ara-C 1.000 mg/m²/12 timer i.v.
English: (1 h), days 26, 46; Ara-C 75 mg/m i.v.
Danish: (1 time), dag 26, 46; Ara-C 75 mg/m² i.v.
English: • adult patients with relapsed or refractory Ph+ ALL as monotherapy.
Danish: • voksne patienter med Ph+ ALL med tilbagefald eller refraktær sygdom som monoterapi.
English: Of a panel of potential comedications (acetaminophen, aciclovir, allopurinol, amphotericin, cytarabine, erythromycin, fluconazole, hydroxyurea, norfloxacin, penicillin V) only erythromycin (IC50 50 μM) and fluconazole (IC50 118 μM) showed inhibition of imatinib metabolism which could have clinical relevance (see section 4.5).
Danish: Af en række potentielle samtidigt administrerede lægemidler (acetaminophen, acicolvir, allopurinol, amphotericin, cytarabin, erythromycin, fluconazol, hydroxyurea, norfloxacin, penicillin V) viste kun erythromycin (IC50 50 µm) og fluconazol (IC50 118 µm) hæmning af imatinib-metabolismen i et omfang der kunne have klinisk betydning.
English: The compound selectively inhibits proliferation and induces apoptosis in Bcr-Abl positive cell lines as well as fresh leukaemic cells from Philadelphia chromosome positive CML and ALL patients.
Danish: Stoffet hæmmer selektivt proliferationen og inducerer apoptosis i Bcr-Ablpositive cellelinier såvel som i friske leukæmiceller fra patienter, der er Philadelphia-kromosom
English: • Feeling dizzy or weak.
Danish: • Føle sig svimmel eller svag.
English: Total bilirubin: >3-10 ULN AST: any
Danish: Total bilirubin > 3-10 ULN
English: Imatinib medac 400 mg capsules are supplied in packs containing 30 capsules in blisters.
Danish: Imatinib medac 400 mg kapsler leveres i pakninger med 30 kapsler i blister.
English: Active substances that may increase imatinib plasma concentrations Substances that inhibit the cytochrome P450 isoenzyme CYP3A4 activity (e.g. protease inhibitors such as indinavir, lopinavir/ritonavir, ritonavir, saquinavir, telaprevir, nelfinavir, boceprevir; azole antifungals including ketoconazole, itraconazole, posaconazole, voriconazole; certain macrolides such as erythromycin, clarithromycin and telithromycin) could decrease metabolism and increase imatinib concentrations.
Danish: Aktive stoffer, der kan øge plasmakoncentrationen af imatinib Stoffer, der hæmmer cytochrom P450 isoenzym CYP3A4-aktiviteten (f.eks. proteasehæmmere som f.eks. indinavir, lopinavir/ritonavir, ritonavir, saquinavir, teleprevir, nelfinavir, boceprevir; azolantimykotika inklusive ketoconazol, itraconazol, posaconazol, voriconazol; visse makrolider som f.eks. erythromycin, clarithromycin og telithromycin), kan nedsætte metaboliseringen og øge koncentrationen af imatinib.
English: Methotrexate (20 mg/m2/week, PO): days 8, 15, 22, 29, 36, 43, 50
Danish: Methotrexat (20 mg/m²/uge, p.o.): dag 8, 15, 22, 29, 36, 43, 50
English: Acute febrile neutrophilic dermatosis (Sweet's syndrome), nail discolouration, angioneurotic oedema, rash vesicular, erythema multiforme, leucocytoclastic vasculitis, Stevens-Johnson syndrome, acute generalised exanthematous pustulosis
Danish: Akut febril neutrofil dermatose (Sweets syndrom), misfarvning af negle, angioødem, vesikulært udslæt, erythema multiforme, leukocytoklastisk vasculitis, Stevens-Johnson syndrom, akut generaliseret eksantematøs
English: Blast crisis is the most
Danish: Blastkrise er den mest fremskredne fase af denne sygdom,
English: • Muscle weakness and spasms with an abnormal heart rhythm (signs of changes in the amount of
Danish: • Muskelsvaghed, kramper og en unormal hjerterytme (tegn på ændringer i mængden af kalium i
English: Imatinib is also an inhibitor of the receptor tyrosine kinases for platelet-derived growth factor (PDGF), PDGF-R, and stem cell factor (SCF), c-Kit, and inhibits PDGF- and SCF-mediated cellular events.
Danish: Imatinib hæmmer også receptortyrosinkinaserne for trombocytafledte vækstfaktorer (PDGF), PDGFR, og stamcellefaktorer (SCF), c-Kit, og hæmmer PDGF- og SCF-medierede cellulære signaler.
English: Target organs for neoplastic changes were the kidneys, urinary bladder, urethra, preputial and clitoral gland, small intestine, parathyroid glands, adrenal glands and non-glandular stomach.
Danish: Målorganerne for neoplastiske ændringer var nyrerne, urinblæren, urinrøret, fedtkirtlerne på forhuden og klitoris, tyndtarmen, biskjoldbruskkirtlerne, binyrerne og den ikke-kirtellignende del af maven.
English: In non-clinical studies, the fertility of male and female rats was not affected (see section 5.3).
Danish: I prækliniske studier var fertiliteten hos han- og hunrotter ikke påvirket (se pkt.
English: Some cases resulted in acute hepatic failure or fulminant hepatitis leading to liver transplantation or a fatal outcome (see section 4.4).
Danish: I nogle tilfælde har dette medført akut leversvigt eller fulminant hepatitis, førende til levertransplantation eller død (se pkt.
English: Thrombosis/embolism* Respiratory, thoracic and mediastinal disorders
Danish: Trombose/emboli* Luftveje, thorax og mediastinum
English: Dose increases from 600 mg to a maximum of 800 mg (given as 400 mg twice daily) in patients with blast crisis may be considered in the absence of severe adverse drug reaction and severe non-leukaemia-related neutropenia or thrombocytopenia in the following circumstances: disease progression (at any time); failure to achieve a satisfactory haematological response after at least 3 months of treatment; failure to achieve a cytogenetic response after 12 months of treatment; or loss of a previously achieved haematological and/or cytogenetic response.
Danish: Dosisøgninger fra 600 mg til maksimalt 800 mg (givet som 400 mg 2 gange dagligt) til patienter i blastkrise kan, hvis der ikke opstår svære bivirkninger og svær ikke-leukæmirelateret neutropeni eller trombocytopeni, overvejes i følgende tilfælde: Sygdomsprogression (til enhver tid), udeblivende tilfredsstillende hæmatologisk respons efter mindst 3 måneders behandling, udeblivende opnåelse af cytogenetisk respons efter 12 måneders behandling, samt hvis tidligere hæmatologisk og/eller cytogenetisk respons ikke genopnås.
English: In the study in patients with unresectable and/or metastatic GIST, both gastrointestinal and intratumoural haemorrhages were reported (see section 4.8).
Danish: I undersøgelsen med patienter med inoperabel og/eller metastaserende GIST rapporteredes både gastrointestinale og intra-tumorale blødninger (se pkt.
English: Induction therapy II
Danish: Induktionsbehandling II
English: INFORMATION IN BRAILLE Imatinib medac 100 mg
Danish: INFORMATION I BRAILLESKRIFT Imatinib medac 100 mg
English: Posology for CML in adult patients
Danish: Dosering ved CML hos voksne patienter
English: If your daily dose is 800 mg, you should take 1 capsule of 400 mg in the morning and 1 capsule of 400 mg in the evening.
Danish: Hvis din daglige dosis er 800 mg skal du tage 1 kapsel med 400 mg om morgenen og 1 kapsel med
English: If cytopenia persists for 4 weeks and is still unrelated to leukaemia, stop imatinib until ANC ≥ 1 x 10
Danish: Hvis cytopeni vedvarer i 4 uger og stadig ikke er leukæmirelateret, seponér imatinib-behandlingen indtil ANC ≥1,0 x 10
English: (1 h), days 1-5
Danish: (1 time), dag 1-5
English: Currently available published data are summarised in section 5.1 but no recommendation on a posology can be made.
Danish: 5.1, men der kan ikke gives nogen anbefaling vedrørende dosering.
English: {2D barcode carrying the unique identifier included.}
Danish: <Der er anført en 2D-stregkode, som indeholder en entydig identifikator.>
English: • Feeling sick (nausea), with loss of appetite, dark-coloured urine, yellow skin or eyes (signs of
Danish: • Have kvalme med tab af appetitten, mørk urin, gul hud eller øjne (tegn på leverproblemer).
English: Paediatric chronic phase CML (at dose 340 mg/m
Danish: Børn med CML i kronisk fase (ved en dosis på 340 mg/m²)
English: • If you are unable to swallow the capsules, you can open them up and pour the powder into a glass of still mineral water or apple juice.
Danish: • Hvis du ikke er i stand til at synke kapslerne, kan du åbne dem og opløse pulveret i et glas
English: One phase II, open label, multicentre clinical trial (study B2225) was conducted including 12 patients with DFSP treated with imatinib 800 mg daily.
Danish: Der er udført et åbent multicenter fase II-klinisk forsøg (studie B2225) med inklusion af 12 patienter med DFSP, som blev behandlet med imatinib 800 mg dagligt.
English: The paediatric patient received 400 mg/m2/daily, subsequently increased to 520 mg/m2/daily.
Danish: (Barnet fik 400 mg/m²/dagligt, der senere blev øget til 520 mg/m²/dagligt).
English: • Rash, red skin with blisters on the lips, eyes, skin or mouth, peeling skin, fever, raised red or purple skin patches, itching, burning sensation, pustular eruption (signs of skin problems).
Danish: • Udslæt, rød hud med små blærer på læber, øjne, hud eller mund, afskallet hud, feber, hævede røde eller lilla hudområder, kløe, brændende fornemmelse, pustuløst udslæt (tegn på
English: The effectiveness of imatinib is based on overall haematological and cytogenetic response rates and progression-free survival.
Danish: Kliniske undersøgelser vedrørende kronisk myeloid leukæmi Imatinibs effekt er baseret på generelle hæmatologiske og cytogene responsrater og progressionsfri overlevelse.
English: If cytopenia is unrelated to leukaemia, reduce dose of imatinib to 400 mg.
Danish: Hvis cytopeni ikke er leukæmirelateret, reducér imatinib-dosis til 400 mg.
English: Papilloma/carcinoma of the preputial/clitoral gland were noted from 30 mg/kg/day onwards, representing approximately 0.5 or 0.3 times the human daily exposure (based on AUC) at 400 mg/day or 800 mg/day, respectively, and 0.4 times the daily exposure in paediatric patients (based on AUC) at 340 mg/m2/day.
Danish: Papillomaer/carcinomer i fedtkirtlerne på forhuden/klitoris blev set fra 30 mg/kg/dag og højere, som svarer til cirka 0,5 eller 0,3 gange den daglige humane eksponering (baseret på AUC) på henholdsvis 400 mg/dag eller 800 mg/dag.
English: Stomatitis, mouth ulceration, gastrointestinal haemorrhage
Danish: Stomatitis, mundulcera, gastrointestinalblødning
English: Imatinib medac 100 mg hard capsules PA-Aluminium/PVC//Aluminium blisters.
Danish: Imatinib medac 100 mg hårde kapsler PA-aluminium/PVC/aluminium blister.
English: Imatinib medac 400 mg hard capsules PA-Aluminium/PVC//Aluminium blisters.
Danish: Imatinib medac 400 mg hårde kapsler PA-aluminium/PVC/aluminium blister.
English: Therefore, caution is recommended when administering imatinib with CYP3A4 substrates with a narrow therapeutic window (e.g. cyclosporin, pimozide, tacrolimus, sirolimus, ergotamine, diergotamine, fentanyl, alfentanil,
Danish: Forsigtighed tilrådes derfor, når imatinib administreres sammen med CYP3A4-substrater med snævert terapeutisk interval (f.eks. cyclosporin, pimozid, tacrolimus, sirolimus, ergotamin, diergotamin, fentanyl, alfentanil, terfenadin, bortezomib, docetaxel og quinidin).
English: Posology for CML in paediatric patients Dosing for paediatric patients should be on the basis of body surface area (mg/m2).
Danish: Dosering til pædiatriske patienter bør baseres på legemsoverfladeareal (mg/m²).
English: Study 0102 38-month data Myeloid blast crisis (n = 260) % of patients (CI95 %)
Danish: (n = 260) % patienter (CI95 %)
English: If you forget to take Imatinib medac • If you forget a dose, take it as soon as you remember.
Danish: • Hvis du glemmer at tage en dosis, så tag den, så snart du kommer i tanker om det.
English: Posology for DFSP in adult patients The recommended dose of imatinib is 800 mg/day for patients with DFSP.
Danish: Dosering ved DFSP hos voksne patienter Den anbefalede dosis af imatinib er 800 mg/dag til patienter med DSFP.
English: Study AJP01 Induction therapy i.v.
Danish: Studie AJP01 Induktionsbehandling
English: Imatinib medac may cause your body to retain water (severe fluid retention).
Danish: Imatinib medac kan forårsage, at din krop begynder at ophobe væske (svær væskeretention).
English: If any of these apply to you, tell your doctor before taking Imatinib medac.
Danish: Hvis noget af det ovenstående gælder for dig, skal du fortælle din læge det, før du tager Imatinib medac.
English: Common: Uncommon: Rare:
Danish: Ikke almindelig: Sjælden:
English: Avascular necrosis/hip necrosis*, growth retardation in children* Renal and urinary disorders
Danish: Avaskulær nekrose/hoftenekrose*, væksthæmning hos børn*
English: • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby,
Danish: • Hvis du er gravid eller ammer, har mistanke om, at du er gravid, eller planlægger at blive gravid, skal du spørge din læge til råds, før du tager dette lægemiddel.
English: Chronic myeloid leukaemia is a form of leukaemia in which certain abnormal white cells (named myeloid cells) start growing out of control.
Danish: Kronisk myeloid leukæmi er en type leukæmi, hvor nogle bestemte unormale hvide blodlegemer (der kaldes myeloide celler) vokser ukontrolleret.
English: • Cough, having difficulty breathing or painful breathing (signs of lung problems).
Danish: • Hoste, åndedrætsbesvær eller smerter ved vejrtrækning (tegn på lungeproblemer).
English: If cytopenia is unrelated to leukaemia, reduce dose of imatinib to 260 mg/m 3.
Danish: Hvis cytopeni ikke er leukæmirelateret, reducér imatinib-dosis til 260 mg/m².
English: • Anorexia, weight loss or a disturbed sense of taste.
Danish: • Appetitløshed, vægttab eller smagsforstyrrelser.
English: Imatinib administration to patients without the genetic translocation generally results in no improvement.
Danish: Der ses generelt ingen bedring ved indgift af imatinib til patienter uden genetisk translokation.
English: Posology for Ph+ ALL in adult patients
Danish: Dosering ved Ph+ ALL hos voksne patienter
English: Blood amylase increased
Danish: Forhøjet serumamylase
English: 9) Musculoskeletal pain during treatment with imatinib or after discontinuation has been observed in post-marketing
Danish: 9 Muskuloskeletale smerter under behandling med imatinib eller efter seponering er blevet
English: G-CSF (5 μg/kg, SC): days 4-13 or until ANC > 1500 post nadir
Danish: G-CSF (5 μg/kg, s.c.): dag 4-13, eller indtil ANC >1500 post nadir
English: A major response combines both complete and partial responses: complete (0 % Ph+ metaphases), partial (1-35 %)
Danish: Cytogenetiske responskriterier: Et hovedrespons kombinerer både fuldstændig og partiel respons: Fuldstændig (0 % Ph metafaser),
English: Paediatric accelerated phase CML and blast crisis (starting dose 340 mg/m
Danish: Børn med CML i accelereret fase og blastkrise (startdosis 340 mg/m²)
English: oral, days 1-7, 15-21;
Danish: ): dag 1-7 og 15-21
English: In Ph+ ALL patients, there is clinical experience of co-administering imatinib with chemotherapy (see section 5.1), but drug-drug interactions between imatinib and chemotherapy regimens are not well characterised.
Danish: Der er klinisk erfaring med administration af imatinib sammen med kemoterapi til patienter med Ph+ ALL, men specifikke interaktionsstudier mellem imatinib og kemoterapiregimer er ikke tilstrækkeligt karakteriseret.
English: Clinical cases of hypothyroidism have been reported in thyroidectomy patients undergoing levothyroxine replacement during treatment with imatinib (see section 4.5).
Danish: Kliniske tilfælde af hypotyroidisme er rapporteret hos patienter, der har fået foretaget tyroidektomi, og som er i levothyroxin-erstatningsterapi samtidig med imatinib-behandling (se pkt.
English: Very common (may affect more than 1 in 10 people) or common (may affect up to 1 in 10 people):
Danish: Meget almindelige (kan forekomme hos flere end 1 ud af 10 personer) eller almindelige (kan forekomme hos op til 1 ud af 10 personer):
English: The most commonly reported (≥ 10 %) treatment-related adverse reactions were mild nausea, vomiting, diarrhoea, abdominal pain, fatigue, myalgia, muscle cramps and rash.
Danish: De mest almindelige rapporterede (≥ 10 %) behandlingsrelaterede bivirkninger var: let kvalme, opkastning, diarré, abdominalsmerter, træthed, myalgi og muskelkramper samt udslæt.
English: (24 h), day 4; DEX 40 mg/day on days 1-4 and 11-14, alternated with MTX 1 g/m i.v.
Danish: DEX 40 mg/dag på dag 1-4 og 11-14, supplerende med MTX 1 g/m² i.v.
English: • Pain or swelling in your abdomen, flatulence, heartburn or constipation.
Danish: • Smerte eller oppustning af maven, luft i maven, halsbrand eller forstoppelse.
English: Rash pustular, contusion, sweating increased, urticaria, ecchymosis, increased tendency to bruise, hypotrichosis, skin hypopigmentation, dermatitis exfoliative, onychoclasis, folliculitis, petechiae, psoriasis, purpura, skin hyperpigmentation,
Danish: Pustuløst udslæt, kontusion, øget svedtendens, urticaria, ecchymose, let til knubs og mærker, hypotrichosis, hypopigmentering af huden, dermatitis exfoliativa, onychoclasi, folliculitis, petechier, psoriasis, purpura, hyperpigmentering af huden, bulløst udslæt
English: Musculoskeletal and connective tissue disorders Very common: Muscle spasm and cramps, musculoskeletal pain including myalgia
Danish: Muskelspasmer og kramper, muskuloskeletale smerter herunder myalgi
English: Imatinib medac 400 mg hard capsules Each hard capsule contains 50.072 mg lactose monohydrate.
Danish: Imatinib medac 400 mg hårde kapsler Hver hårde kapsel indeholder 50,072 mg lactosemonohydrat.
English: Flushing, haemorrhage
Danish: Flushing, blødning
English: (24 h), day 1; Etoposide 250 mg/m i.v.
Danish: (24 timer), dag 1; Etoposid 250 mg/m² i.v.
English: Check with your doctor, pharmacist or nurse if you are not sure.
Danish: Spørg lægen, på apoteket eller sundhedspersonalet, hvis der er noget, du er i tvivl om.
English: Concomitant use of imatinib and medicinal products that induce CYP3A4 (e.g. dexamethasone, phenytoin, carbamazepine, rifampicin, phenobarbital or Hypericum perforatum, also known as St. John's Wort) may significantly reduce exposure to imatinib, potentially increasing the risk of therapeutic failure.
Danish: Samtidig anvendelse af imatinib og lægemidler, der inducerer CYP3A4 (f.eks. dexamethason, phenytoin, carbamazepin, rifampicin, phenobarbital eller Hypericum perforatum, også kendt som prikbladet perikum) kan signifikant reducere følsomheden over for imatinib, og dermed potentielt øge risikoen for terapeutisk svigt.
English: However, always take this medicine exactly as your doctor, pharmacist or nurse has told you.
Danish: Tag altid lægemidlet nøjagtigt efter lægens eller apotekspersonalets anvisning.
English: Posology modification
Danish: Ændring af dosering
English: Posology for Ph+ ALL in children
Danish: Dosering ved Ph+ ALL hos børn
English: DEX (6 mg/m2/day, PO): days 1-7 and 15-21
Danish: DEX (6 mg/m²/dag, p.o.): dag 1-7 og 15-21
English: Imatinib medac is also a treatment for children and adolescents with CML.
Danish: Imatinib medac bruges også til behandling af børn og unge med CML.
English: CP 200 mg/m i.v., days 3-5; MTX 15 mg intrathecal, day 1
Danish: CP 200 mg/m² i.v., dag 3, 4, 5; MTX 12 mg intrathecal, dag 1
English: Imatinib medac contains lactose.
Danish: Imatinib medac indeholder lactose.
English: In the event of recurrence of ANC < 1.0 x 10
Danish: I tilfælde af tilbagevenden af ANC <1,0 x 10
English: If this applies to you, tell your doctor without taking Imatinib medac.
Danish: Hvis dette gælder for dig, skal du fortælle din læge det, før du tager Imatinib medac.