FrancophonIA/ELRC3.0 huggingface dataset:
English: Pravastatin is contraindicated during pregnancy and should be administered to women of childbearing potential only when such patients are unlikely to conceive and have been informed of the potential risk.
Slovenian: Pravastatin je med nosečnostjo kontraindiciran in se lahko daje ženskam v rodni dobi le, če je malo verjetno, da bodo te bolnice zanosile, in če so bile obveščene o možnem tveganju.
English: In all clinical trials, patients were instructed to take Pravafenix daily during the evening meal and dietary restrictions instituted before therapy should be continued.
Slovenian: V vseh kliničnih študijah je bilo bolnikom dano navodilo, da jemljejo zdravilo Pravafenix vsak dan med večernim obrokom in da še naprej upoštevajo dietne omejitve, vpeljane pred zdravljenjem.
English: Frequency categories are based on information available from pravastatin and fenofibrate Summary of Product characteristics available in the EU.
Slovenian: Kategorije pogostnosti temeljijo na informacijah iz Povzetka glavnih značilnosti zdravila za pravastatin in fenofibrat, ki je na voljo v EU.
English: If you take indigestion remedies (used to neutralise acid in your stomach), take Pravafenix 1 hour after.
Slovenian: Če jemljete zdravila za prebavne težave (za nevtralizacijo kisline v želodcu), vzemite zdravilo Pravafenix eno uro kasneje.
English: Interaction between pravastatin and fusidic acid can lead to an increased risk of rhabdomyolysis.
Slovenian: Medsebojno delovanje pravastatina in fusidne kisline lahko privede do povečanega tveganja za rabdomiolizo.
English: If you are not sure about this, please follow your doctor's advice.
Slovenian: Če ste v dvomu, upoštevajte nasvet zdravnika.
English: Additional adverse reactions associated with the use of medicinal products containing pravastatin or fenofibrate observed in clinical trials and postmarketing experience that may potentially occur with Pravafenix are listed below.
Slovenian: Dodatni neželeni učinki, povezani z uporabo zdravil, ki vsebujejo pravastatin ali fenofibrat, ki so jih opazili v kliničnih študijah in pri izkušnjah z zdravilom po začetku trženja in do katerih lahko pride pri uporabi zdravila Pravafenix, so našteti spodaj.
English: In the majority of cases, liver transaminase levels have returned to their baseline value without the need for treatment discontinuation.
Slovenian: Pri večini primerov so ravni jetrnih transaminaz padle na izhodiščno vrednost, ne da bi bilo treba zdravljenje prekiniti.
English: Additionally, fibrates have the properties to modify the size and density of LDL-C particles to make them less atherogenic.
Slovenian: Poleg tega imajo fibrati lastnosti, s katerimi lahko spreminjajo velikost in gostoto delcev holesterola LDL in jih tako spreminjajo v manj aterogene.
English: Sleep disturbance including insomnia and nightmares
Slovenian: Psihiatrične motnje motnje spanja, vključno z nespečnostjo in nočnimi morami občasni
English: Clinical and biochemical monitoring of patients receiving this combination is recommended.
Slovenian: Pri bolnikih, ki prejemajo to kombinacijo, je priporočeno spremljanje kliničnih in biokemičnih parametrov.
English: Thromboembolism (pulmonary embolism, deep vein thrombosis)*
Slovenian: Žilne bolezni tromboembolija (pljučna embolija, globoka venska tromboza)*
English: Pravafenix has no or negligible influence on the ability to drive and use machines.
Slovenian: Zdravilo Pravafenix nima ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja s stroji.
English: Following oral administration, 20% of the initial dose is eliminated in the urine and 70% in the faeces.
Slovenian: Po peroralni uporabi se 20 % začetnega odmerka izloči z urinom, 70 % pa z blatom.
English: The medicine must be discontinued because of the potential risk to the foetus.
Slovenian: Jemanje zdravila je treba zaradi možnega tveganja za plod prekiniti.
English: Each hard capsule contains 19 mg of lactose.
Slovenian: Ena trda kapsula vsebuje 19 mg laktoze.
English: Do not take Pravafenix if any of the above applies to you.
Slovenian: Ne vzemite zdravila Pravafenix, če kaj od naštetega velja za vas.
English: Abnormal urination (including dysuria, frequency, nocturia)
Slovenian: nenormalno uriniranje (vključno z dizurijo, pogostim uriniranjem, nikturijo)
English: 14 hard capsules 30 hard capsules 60 hard capsules 90 hard capsules
Slovenian: 14 trdih kapsul 30 trdih kapsul 60 trdih kapsul 90 trdih kapsul
English: Interactions relevant to fenofibrate
Slovenian: Interakcije, povezane s fenofibratom
English: • Tiredness, weakness, influenza-like illness.
Slovenian: • utrujenost, oslabelost, gripi podobno bolezensko stanje,
English: Presenting features can include dyspnoea, non-productive cough and deterioration in general health (fatigue, weight loss and fever).
Slovenian: Med simptomi in znaki so lahko dispneja, neproduktiven kašelj in poslabšanje splošnega zdravstvenega stanja (utrujenost, hujšanje in vročina).
English: Maximum plasma concentrations (Cmax) occur within 4 to 5 hours after oral administration.
Slovenian: Najvišja koncentracija v plazmi se pojavi v 4 do 5 urah po peroralni uporabi.
English: Concomitant administration of pravastatin and ciclosporin leads to an approximately 4 fold increase in pravastatin systemic exposure.
Slovenian: Sočasna uporaba pravastatina in ciklosporina vodi k približno štirikratnemu povečanju sistemske izpostavljenosti pravastatina.
English: The baseline CK levels may also be useful as a reference in the event of a later increase during the combination therapy.
Slovenian: Izhodiščne vrednosti kreatin-fosfokinaze so lahko uporabne tudi kot referenčne, če do zvišanja pride kasneje, med kombiniranim zdravljenjem.
English: If you feel any of these symptoms you should stop taking Pravafenix and inform your doctor.
Slovenian: Če imate kateregakoli od teh simptomov, morate z jemanjem zdravila Pravafenix prenehati in o tem obvestiti zdravnika.
English: This occurrence may represent a failure of efficacy in patients with severe hypertriglyceridaemia, a direct medicinal product effect, or a secondary phenomenon mediated through biliary tract stone or sludge formation, resulting in the obstruction of the common bile duct.
Slovenian: To lahko kaže na neučinkovitost zdravila pri bolnikih s hudo hipertrigliceridemijo, kar je neposredna posledica zdravila, ali pa gre za sekundarni pojav, ki nastane zaradi kamna ali usedline v biliarnem traktu, ki ovira žolčevod.
English: In the event of an overdose, symptomatic and supportive measures should be employed.
Slovenian: V primeru prevelikega odmerjanja je potrebno začeti simptomatsko in podporno zdravljenje.
English: In a similar study with clarithromycin a statistically significant increase in AUC (110%) and Cmax (127%) was observed.
Slovenian: V podobni študiji s klaritromicinom so opazili statistično pomembno zvišanje površine pod krivuljo (110 %) in Cmax (127 %).
English: Prior to initiating Pravafenix, secondary causes of combined dyslipidaemia should be excluded and patients should be placed on a standard cholesterol and triglycerides-lowering diet which should be continued during treatment.
Slovenian: Pred začetkom zdravljenja z zdravilom Pravafenix je treba izključiti sekundarne vzroke za kombinirano dislipidemijo, bolnikom pa mora biti predpisana standardna dieta za zniževanje vrednosti holesterola in trigliceridov, ki se je morajo držati tudi med zdravljenjem.
English: The major degradation product of pravastatin is the 3-αhydroxy isomeric metabolite.
Slovenian: Glavni produkt razgradnje pravastatina je izomerni metabolit 3-α-hidroksi.
English: In such cases CK levels should be measured (see below).
Slovenian: V takih primerih je treba izmeriti vrednosti kreatin-fosfokinaze (glejte spodaj).
English: Pravafenix must be taken with food, as food enhances the bioavailability of fenofibrate (see sections 4.2 and 5.2).
Slovenian: Zdravilo Pravafenix je treba jemati s hrano, saj hrana zviša biološko uporabnost fenofibrata (glejte poglavji 4.2 in 5.2).
English: Although these changes were minor, caution should be exercised when associating pravastatin with erythromycin or clarithromycin.
Slovenian: Čeprav gre za manjše spremembe, je pri sočasnem jemanju pravastatina z eritromicinom ali klaritromicinom potrebna previdnost.
English: - Before starting taking Pravafenix, you should be on a diet to lower your cholesterol.
Slovenian: - Pred začetkom jemanja zdravila Pravafenix morate biti na dieti za zniževanje holesterola.
English: It contains two active substances: pravastatin and fenofibrate.
Slovenian: Vsebuje dve zdravilni učinkovini: pravastatin in fenofibrat.
English: In exceptional circumstances, where prolonged systemic fusidic acid is needed e.g for the treatment of severe infections, the need for co-administration of pravastatin and fusidic acid should only be considered on a case by case basis and under close medical supervision.
Slovenian: izjemnih okoliščinah, ko je potrebno podaljšano sistemsko zdravljenje s fusidno kislino, npr. za zdravljenje hudih okužb, je sočasna uporaba pravastatina in fusidne kisline upoštevna le v posameznih primerih in pod strogim zdravniškim nadzorom.
English: The plasma concentrations are proportional to the doses administered.
Slovenian: Koncentracije v plazmi so sorazmerne uporabljenim odmerkom.
English: The systemic clearance of pravastatin is 0.81 l/h/kg and the renal clearance is 0.38 l/h/kg indicating tubular secretion.
Slovenian: Sistemski očistek pravastatina je 0,81 l/h/kg, ledvični očistek pa 0,38 l/h/kg, kar kaže na tubularno sekrecijo.
English: In one of two interaction studies with pravastatin and erythromycin a statistically significant increase in the area under the curve (AUC) (70%) and Cmax (121%) of pravastatin was observed.
Slovenian: V enih od dveh študij medsebojnega delovanja s pravastatinom in eritromicinom so opazili statistično pomembno zvišanje površine pod krivuljo (AUC) (70 %) in Cmax (121 %) za pravastatin.
English: Fenofibrate is a fibric acid derivative whose lipid modifying effects reported in humans are mediated via activation of Peroxisome Proliferator Activated Receptor type alpha (PPARα).
Slovenian: Fenofibrat je derivat fibrične kisline (fibrat), katerega vpliv na lipide, o katerem poročajo pri ljudeh, se posreduje z aktivacijo s peroksisomskim proliferatorjem aktiviranega receptorja alfa (PPARα).
English: In line with several formulations for fenofibrate, the fixed combination is recommended to be taken with food because the bioavailability of fenofibrate is increased when administered with food and the lipid-lowering efficacy of pravastatin is not altered.
Slovenian: V skladu z več pripravki za fenofibrat je priporočljivo, da se fiksna kombinacija vzame s hrano, saj se biološka uporabnost fenofibrata pri jemanju s hrano poveča, učinkovitost pravastatina pri zniževanju koncentracije lipidov pa se ne spremeni.
English: Studies with fenofibrate on lipoprotein fractions show decreases in levels of LDL and VLDL cholesterol.
Slovenian: Študije vpliva fenofibrata na frakcije lipoproteinov kažejo znižanje ravni holesterola LDL in VLDL.
English: Embryotoxic effects have been shown at doses in the range of maternal toxicity (see section 5.3).
Slovenian: Embriotoksični učinki so dokazani v odmerkih, pri katerih se je kazala tudi toksičnost za mater (glejte poglavje 5.3).
English: Some evidence suggests that statins as a class raise blood glucose and in some patients, at high risk of future diabetes, may produce a level of hyperglycaemia where formal diabetes care is appropriate.
Slovenian: Nekateri dokazi kažejo, da statini kot razred zdravil povišajo raven glukoze in lahko pri nekaterih bolnikih z velikim tveganjem za razvoj sladkorne bolezni ustvarijo hiperglikemijo, ki zahteva uradno oskrbo sladkorne bolezni.
English: The safety of concomitant administration of pravastatin and fenofibrate was assessed in rats.
Slovenian: Varnost sočasne uporabe pravastatina in fenofibrata so ocenjevali na podganah.
English: The respective effects of pravastatin and fenofibrate are complementary.
Slovenian: Individualni učinki pravastatina in fenofibrata se med seboj dopolnjujejo.
English: - capsule shell: gelatine, indigo carmine (E132), black iron oxide (E172), titanium dioxide (E171), yellow iron oxide (E172).
Slovenian: - ovoj kapsul: želatina, indigotin (E132), črni železov oksid (E172), titanov dioksid (E171),
English: Concomitant administration resulted in approximately 40 to 50% decrease in the bioavailability of pravastatin.
Slovenian: Zaradi sočasnega dajanja se je biološka uporabnost pravastatina zmanjšala za 40 do 50 %.
English: In elderly patients, the fenofibric acid apparent total plasma clearance is not modified.
Slovenian: Pri starejših pacientih se navidezni skupni očistek fenofibratne kisline ne spremeni.
English: LDL and VLDL triglycerides are reduced.
Slovenian: Ravni trigliceridov LDL in VLDL se znižajo.
English: You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in your blood, are overweight and have high blood pressure.
Slovenian: Verjetno je, da imate tveganje za razvoj sladkorne bolezni, če imate visoke ravni sladkorjev in maščob v krvi, imate čezmerno telesno maso in visok krvi tlak.
English: If CK levels are significantly elevated > 5 times the ULN at baseline, the results should be controlled after 5-7 days.
Slovenian: Če se vrednosti kreatin-fosfokinaze znatno povečajo, tj. če so večje od petkratne zgornje meje normalnih vrednosti glede na izhodiščno vrednost, je treba rezultate v petih do sedmih dneh ponovno preveriti.
English: • The active substances are fenofibrate and pravastatin.
Slovenian: • Zdravilni učinkovini sta fenofibrat in pravastatin.
English: Medicinal products metabolised by cytochrome P450
Slovenian: Zdravila, ki se presnavljajo s citokromom P450
English: This metabolite has one-tenth to one-fortieth the HMG-CoA reductase inhibitor activity of the parent compound.
Slovenian: Ta metabolit ima od ene desetine do ene štiridesetine aktivnosti zaviralca reduktaze HMG-CoA matične spojine.
English: - Gallbladder disease (see section 4.4).
Slovenian: - Bolezen žolčnika (glejte poglavje 4.4).
English: Repeated dose studies indicate that pravastatin may induce varying degrees of hepatotoxicity and myopathy; in general, substantive effects on these tissues were only evident at doses 50 or more times the maximum human mg/kg dose.
Slovenian: Študije toksičnosti pri ponavljajočih se odmerkih kažejo, da lahko pravastatin sproži različne stopnje hepatotoksičnosti in miopatije; v splošnem so bili znatni učinki na ta tkiva opazni šele pri odmerkih, ki so znašali 50-kratnik največjega odmerka pri človeku v mg/kg ali več.
English: Vision disturbance (including blurred vision and diplopia)
Slovenian: Očesne bolezni motnje vida (vključno z zamegljenim vidom in diplopijo)
English: The presence of food in the gastrointestinal tract leads to a reduction in the bioavailability, but the cholesterol-lowering effect of pravastatin is identical whether taken with or without food.
Slovenian: Če je v gastrointestinalnem traktu prisotna hrana, se biološka uporabnost zmanjša, učinek pravastatina na zniževanje koncentracije holesterola pa je enak, ne glede na to, ali je zdravilo zaužito skupaj s hrano ali ne.
English: When measured, CK levels should be interpreted in the context of other potential factors that can cause transient muscle damage, such as strenuous exercise or muscle trauma and repeated if necessary.
Slovenian: Pri merjenju je treba vrednosti kreatin-fosfokinaze razlagati skupaj z drugimi potencialnimi dejavniki, ki lahko povzročijo prehodno poškodbo mišic, npr. z naporno telesno dejavnostjo, in merjenje po potrebi ponoviti.
English: Rare side effects (may affect up to 1 in 1,000 people) • Decrease in haemoglobin (oxygen-carrying pigment in blood) and leukocytes (white blood cells).
Slovenian: Redki neželeni učinki (pojavijo se pri 1 do 10 bolnikih od 10 000 bolnikov) • znižanje hemoglobina (krvnega barvila, ki prenaša kisik) in levkocitov (belih krvničk).
English: LDL cholesterol is often called ‘bad' cholesterol because it can build up in the walls of your arteries and form plaque.
Slovenian: Holesterol LDL pogosto imenujemo „slabi“ holesterol, ker se lahko kopiči v stenah arterij in tako povzroči nastanek oblog.
English: EU/1/11/679/007 14 hard capsules EU/1/11/679/004 30 hard capsules EU/1/11/679/005 60 hard capsules EU/1/11/679/006 90 hard capsules
Slovenian: EU/1/11/679/007, 14 trdih kapsul EU/1/11/679/004, 30 trdih kapsul EU/1/11/679/005, 60 trdih kapsul EU/1/11/679/006, 90 trdih kapsul
English: Therefore, caution should be exercised in patients with history of pulmonary embolism.
Slovenian: Zato je pri bolnikih, ki imajo v anamnezi pljučno embolijo, potrebna previdnost.
English: The absence of a significant pharmacokinetic interaction with pravastatin has been specifically demonstrated for several medicinal products, particularly those that are substrates/inhibitors of CYP3A4 e.g. diltiazem, verapamil, itraconazole, ketoconazole, protease inhibitors, grapefruit juice and CYP2C9 inhibitors (e.g. fluconazole).
Slovenian: Odsotnost pomembnih farmakokinetičnih interakcij s pravastatinom je še posebej dokazana pri posameznih zdravilih, zlasti pri tistih, ki so substrati/zaviralci encima CYP3A4, npr. pri diltiazemu, verapamilu, itrakonazolu, ketokonazolu, zaviralcih proteaz, soku grenivke in zaviralcih encima CYP2C9 (npr. flukonazolu).
English: Embryotoxic effects were observed at doses in the range of maternal toxicity.
Slovenian: Opazili so embriotoksične učinke v odmerkih, katerih količine so bile v okviru količin toksičnosti pri materi.
English: The frequencies of adverse reactions are ranked according to the following: Very common ( ≥ 1/10),
Slovenian: Neželeni učinki so po pogostnosti razvrščeni takole: Zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do
English: The name of your medicine is Pravafenix.
Slovenian: Vaše zdravilo se imenuje Pravafenix.
English: There are no data on the excretion of fenofibrate and/or its metabolites into human breast milk.
Slovenian: O izločanju fenofibrata in/ali njegovih presnovkov v materino mleko ni podatkov.
English: Fenofibrate may increase cholesterol excretion into the bile, potentially leading to cholelithiasis.
Slovenian: Fenofibrat lahko poveča izločanje holesterola v žolč, kar lahko vodi do holelitiaze.
English: As with other lipid lowering medicinal products, moderate increases in transaminase levels have been reported in some patients treated with pravastatin or fenofibrate.
Slovenian: Tako kot pri drugih zdravilih za zniževanje lipidov so pri nekaterih bolnikih, ki so se zdravili s pravastatinom ali fenofibratom, poročali o zmernem zvišanju ravni transaminaz.
English: Plasma elimination half-life of oral pravastatin is 1.5 to 2 hours.
Slovenian: Razpolovni časizločanja peroralno zaužitega pravastatina v plazmi je od 1,5 do 2 uri.
English: - Moderate to severe renal impairment (defined as an estimated creatinine clearance < 60 ml/min).
Slovenian: - Blaga do zmerna okvara ledvic (ki je določena z ocenjenim očistkom kreatinina < 60 ml/min).
English: When your doctor has prescribed Pravafenix along with colestyramine or any other bile acid binding resins (medicines for lowering cholesterol), take Pravafenix 1 hour before, or 4 to 6 hours after the resin.
Slovenian: Če vam je zdravnik predpisal zdravilo Pravafenix skupaj s holestiraminom ali s katerokoli drugo smolo, ki veže žolčno kislino (zdravilom za zniževanje holesterola), vzemite zdravilo Pravafenix eno uro pred smolo ali 4 do 6 ur po njej.
English: There was no clinically significant decrease in bioavailability or therapeutic effect when pravastatin was administered one hour before or four hours after colestyramine or one hour before colestipol.
Slovenian: Klinično pomembnega znižanja biološke uporabnosti ali terapevtskega učinka ni bilo, če je bil pravastatin vzet eno uro pred holestiraminom ali štiri ure po njem ter eno uro pred holestipolom.
English: Your total cholesterol is made up mainly of LDL and HDL cholesterol.
Slovenian: Celotni holesterol v glavnem sestavljata holesterol LDL in holesterol HDL.
English: • The other ingredients are: - capsule content: lactose monohydrate, cellulose microcrystalline, ascorbyl palmitate, povidone, sodium starch glycolate, magnesium stearate, talc, triacetin, sodium hydrogen carbonate, lauroyl macrogolglycerides, hydroxypropylcellulose, macrogol 20 000.
Slovenian: • Pomožne snovi so: - vsebina kapsule: laktoza monohidrat, mikrokristalna celuloza, askorbilpalmitat, povidon, natrijev karboksimetilškrob, magnezijev stearat, smukec, triacetin, natrijev hidrogenkarbonat, lauroil makrogolgliceridi, hidroksipropilceluloza, makrogol 20 000.
English: Pravafenix contains fenofibrate and pravastatin, which have different modes of action and show additive effects in terms of reduction of serum lipid.
Slovenian: Farmakodinamični učinki Zdravilo Pravafenix vsebuje fenofibrat in pravastatin, ki imata različen način delovanja in v smislu zniževanja serumskih lipidov izkazujeta aditivno delovanje.
English: It is rapidly absorbed; peak serum levels are achieved 1 to 1.5 hours after ingestion.
Slovenian: Absorbira se hitro; najvišje serumske vrednosti so dosežene v uri do uri in pol po zaužitju.
English: What Pravafenix is and what it is used for What you need to know before you take Pravafenix How to take Pravafenix
Slovenian: Kaj je zdravilo Pravafenix in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Pravafenix Kako jemati zdravilo Pravafenix Možni neželeni učinki
English: - Your doctor may also want you to have blood tests to check how well your liver is working after you start taking Pravafenix.
Slovenian: - Zdravnik bo morda pri vas želel opraviti preiskavo krvi tudi po tem, ko ste že začeli jemati zdravilo Pravafenix; tako bo preveril, ali vaša jetra dobro delujejo.
English: - Fusidic acid: do not take fusidic acid (a medicine for bacterial infections) while using this medicine.
Slovenian: - s fusidno kislino: dokler uporabljate to zdravilo, ne jemljite fusidne kisline (zdravila za bakterijske okužbe).
English: Consequently, the potential benefit/risk ratio of Pravafenix should be closely assessed before treatment initiation and patients should be monitored for any signs of muscle toxicity.
Slovenian: Zato je treba pred začetkom zdravljenja skrbno oceniti razmerje med morebitnimi koristmi in tveganji zdravila Pravafenix, pri bolnikih pa spremljati, ali so se pojavili kakršnikoli simptomi toksičnih učinkov na mišice.
English: Fenofibrate is excreted in milk of female rat.
Slovenian: Fenofibrat se izloča v mleko samic podgan.
English: In these cases, CK levels should be measured.
Slovenian: V teh primerih je treba izmeriti vrednosti kreatin fosfokinaze.
English: The risk of myopathy including rhabdomyolysis may be increased by the concomitant administration of systemic fusidic acid with statins.
Slovenian: Tveganje za miopatijo, vključno z rabdomiolizo, se lahko poveča pri sistemskem zdravljenju s fusidno kislino ob sočasni uporabi statinov.
English: of fenofibric acid (point estimate) is of 30.94%, 10.9% and
Slovenian: Cmax fenofibratne kisline (ocenjena vrednost) znaša 30,94 %, 10,9 % in 68,71 %.
English: The following statements reflect the information available on the individual active substances (fenofibrate and pravastatin).
Slovenian: Spodnje navedbe odražajo dostopne podatke o posameznih zdravilnih učinkovinah (fenofibratu in pravastatinu).
English: If an overdose is suspected, treat symptomatically and institute appropriate supportive measures as required.
Slovenian: Če obstaja sum na preveliko odmerjanje, zdravite simptomatsko in po potrebi uvedite ustrezne podporne ukrepe.
English: The capsules are supplied in Polyamide-Aluminium-PVC/aluminium blister packs containing 30, 60, or 90 capsules, and in opaque white plastic bottles containing either 14, 30, 60 or 90 capsules.
Slovenian: Kapsule so na voljo v pretisnih omotih iz poliamidaaluminija-PVC/aluminija, ki vsebujejo 30, 60 in 90 trdih kapsul, in v neprozornih belih plastenkah s 14, 30, 60 ali 90 kapsulami.
English: The usual dose is one capsule taken daily during the evening meal.
Slovenian: Običajni odmerek za odrasle je ena kapsula dnevno, ki se zaužije med večernim obrokom.