FrancophonIA/ELRC3.0 huggingface dataset:
English: Coronary heart disease and cerebrovascular disease As with any antihypertensive agents, excessive blood pressure decrease in patients with ischaemic cardiovascular and cerebrovascular disease could result in a myocardial infarction or stroke.
Slovenian: Koronarna srčna bolezen in možganskožilna bolezen Tako kot pri drugih antihipertenzivih lahko preveliko znižanje krvnega tlaka pri bolnikih z ishemično srčnožilno in možganskožilno boleznijo povzroči miokardni infarkt ali možgansko kap.
English: The results showed that the treatment with Losartan (327 events) as compared with placebo (359 events) resulted in a 16.1 % risk reduction (p = 0.022) in the number of patients reaching the primary composite endpoint.
Slovenian: Rezultati so pokazali, da je bilo pri zdravljenju z losartanom (327 dogodkov) v primerjavi s placebom (359 dogodkov) tveganje za primarni sestavljeni opazovani dogodek (v številu bolnikov, ki so doživeli primarni sestavljeni opazovani dogodek) manjše za 16,1 % (p = 0,022).
English: Neither Losartan nor the active metabolite can be removed by haemodialysis.
Slovenian: Niti losartana niti njegovega aktivnega presnovka ni možno odstraniti s hemodializo.
English: Based on pharmacokinetic data which demonstrate significantly increased plasma concentrations of losartan in cirrhotic patients, a lower dose should be considered for patients with a history of hepatic impairment.
Slovenian: Izhajajoč iz farmakokinetičnih podatkov, ki izkazujejo signifikantno povečanje koncentracije losartana v plazmi pri cirotičnih bolnikih, je treba pri bolnikih z okvaro jeter v anamnezi razmisliti o zmanjšanju odmerka.
English: Hypertension and type 2 diabetes with renal disease In a controlled clinical trial in type 2 diabetic patients with proteinuria (RENAAL study, see section 5.1) the most common drug-related adverse events which were reported for losartan are as follows: Nervous system disorders: common: dizziness
Slovenian: Hipertenzija in sladkorna bolezen tipa 2 z boleznijo ledvic V kontroliranem kliničnem preizkušanju pri bolnikih s sladkorno boleznijo tipa 2 s proteinurijo (študija RENAAL, glejte poglavje 5.1) so najpogostejši z zdravilom povezani neželeni učinki, o katerih so poročali za losartan, sledeči:
English: Co-medication is not advisable.
Slovenian: Sočasna uporaba ni priporočljiva.
English: Therefore the results observed with losartan in comparison with atenolol in the LIFE study with regard to cardiovascular morbidity/mortality do not apply for black patients with hypertension and left ventricular hypertrophy.
Slovenian: Zato rezultati glede srčno-žilne obolevnosti/smrtnosti iz študije LIFE za losartan v primerjavi z atenololom ne veljajo za bolnike črne rase s hipertenzijo in hipertrofijo levega prekata.
English: Infants whose mothers have taken losartan should be closely observed for hypotension (see also section 4.3 and 4.4).
Slovenian: Otroke, katerih matere so prejemale losartan, je treba pozorno spremljati zaradi možnosti pojava hipotenzije (glejte poglavji 4.3 in 4.4).
English: HDPE bottles of 100 or 300 tablets.
Slovenian: HDPE plastenke po 100 ali 300 tablet.
English: The plasma concentrations of the active metabolite are not altered in patients with renal impairment or in heamodialysis patients.
Slovenian: Plazemske koncentracije aktivnega presnovka se pri bolnikih z okvaro ledvic ali bolnikih na hemodializi ne razlikujejo.
English: Special caution is necessary when you are treated with a ß-blocker concomitantly,
Slovenian: Posebna previdnost je potrebna, če sočasno jemljete beta zaviralec.
English: WEEK 3 (day 15-21) 1 tablet = 50 mg daily
Slovenian: TEDEN (15.-21. dan) 1 tableta = 50 mg dnevno
English: Immune system disorders: rare: hypersensitivity: anaphylactic reactions, angiooedema including swelling of the larynx and glottis causing airway obstruction and/or swelling of the face, lips, pharynx, and/or tongue; in some of these patients angiooedema had been reported in the past in connection with the administration of other medicines, including ACE inhibitors; vasculitis, including Henoch-Schonlein purpura.
Slovenian: Bolezni imunskega sistema redke: preobčutljivost: anafilaktične reakcije, angioedem vključno z otekanjem grla in glotisa, zaradi česar se zožijo dihalne poti in/ali otekanjem obraza, ustnic, žrela in/ali jezika - pri nekaterih od teh bolnikov so v preteklosti poročali o angioedemu v povezavi z jemanjem drugih zdravil, vključno z zaviralci ACE; vaskulitis vključno s Henoch-Schoenleinovo purpuro Bolezni živčevja pogostnost ni znana: migrena
English: In some patients the dose may later be increased to 100 mg losartan (two tablets Cozaar 50 mg) once daily
Slovenian: Pri nekaterih bolnikih se odmerek kasneje lahko poveča na 100 mg losartana (dve tableti Cozaar 50 mg) enkrat na dan.
English: In the ELITE II Study Losartan 50 mg once daily (starting dose 12.5 mg, increased to 25 mg, then 50 mg once daily) was compared with captopril 50 mg three times daily (starting dose 12.5 m, increased to 25 mg and then to 50 mg three times daily).
Slovenian: V študiji ELITE II so losartan 50 mg enkrat na dan (začetni odmerek 12,5 mg, povečan na 25 mg, nato 50 mg enkrat na dan) primerjali s kaptoprilom 50 mg trikrat na dan (začetni odmerek 12,5 mg, povečan na 25 mg in nato 50 mg trikrat na dan).
English: 1 tablet = 12,5 mg daily Use this card first
Slovenian: 1 tableta = 12,5 mg dnevno Najprej porabite tablete s te ploščice.
English: non-steroidal anti-inflammatory drugs such as indomethacin, including cox-2-inhibitors (medicines that reduce inflammation, and can be used to help relieve pain) as they may reduce the blood lowering effect of losartan.
Slovenian: • nesteroidne antirevmatike, kot je indometacin, vključno z zaviralci COX-2 (zdravila, ki zdravijo vnetje in se lahko uporabljajo za odpravljanje bolečine), ker lahko zmanjšajo losartanov učinek znižanja krvnega tlaka.
English: WEEK 4 (day 22-28) 1 tablet = 50 mg daily
Slovenian: TEDEN (22.-28. dan) 1 tableta = 50 mg dnevno
English: Cozaar may be administered with other antihypertensive agents, especially with diuretics (e.g. hydrochlorothiazide).
Slovenian: Zdravilo Cozaar se lahko jemlje skupaj z drugimi antihipertenzivnimi zdravili, še posebej z diuretiki (npr. hidroklorotiazidom).
English: As a consequence of inhibiting the renin-angiotensin system, changes in renal function including renal failure have been reported (in particular, in patients whose renal function is dependent on the renin angiotensin aldosterone system such as those with severe cardiac insufficiency or pre-existing renal dysfunction).
Slovenian: Kot posledico inhibicije sistema renin-angiotenzin so poročali o spremembah ledvične funkcije, vključno z ledvično odpovedjo (še posebej pri bolnikih, katerih ledvična funkcija je odvisna od sistema renin-angiotenzin-aldosteron, kot je pri bolnikih s hudo srčno insuficienco ali že obstoječo ledvično disfunkcijo).
English: It was found that concomitant treatment of losartan with rifampicine (inducer of matabolism enzymes) gave a 40% reduction in plasma concentration of the active metabolite.
Slovenian: Ugotovili so, da je pri sočasnem zdravljenju z losartanom in rifampicinom (induktor presnovnih encimov) plazemska koncentracija aktivnega presnovka manjša za 40 %.
English: • fainting (syncope),
Slovenian: • omedlevica (sinkopa)
English: It is not known whether losartan is excreted in human milk.
Slovenian: Ni znano, če se losartan izloča v materino mleko.Vendar pa se losartan izloča v materino mleko pri podganah.
English: In this study losartan was generally well tolerated, as shown by a therapy discontinuation rate on account of adverse events that was comparable to the placebo group.
Slovenian: V tej študiji so bolniki losartan na splošno dobro prenašali, na kar kaže podobno število prekinitev zdravljenja zaradi neželenih učinkov kot pri placebu.
English: The rates of cardiovascular death and myocardial infarction were not significantly different between the treatment groups.
Slovenian: Deleži smrti zaradi srčno-žilnih vzrokov in miokardnega infarkta med obema skupinama niso bili pomembno različni.
English: After discontinuation of Losartan, PRA and angiotensin II values fell within three days to the baseline values.
Slovenian: Po prekinitvi zdravljenja z losartanom so aktivnost renina v plazmi in vrednosti angiotenzina II v treh dneh padle na začetne vrednosti.
English: These conditions should be corrected prior to administration of <COZAAR>, or a lower starting dose should be used (see section 4.2).
Slovenian: Tovrstna stanja moramo uravnati pred uporabo zdravila <COZAAR> oz. moramo uporabiti nižji začetni odmerek (glejte poglavje 4.2).
English: PHARMACEUTICAL FORM AND CONTENTS 100 or 300 tablets.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 100 ali 300 tablet.
English: The other ingredients are microcrystalline cellulose (E460), lactose monohydrate, pregelatinized maize starch, magnesium stearate (E572), hydroxypropyl cellulose (E463), hypromellose (E464).
Slovenian: Pomožne snovi so: mikrokristalna celuloza (E460), laktoza monohidrat, predgeliran koruzni škrob, magnezijev stearat (E572), hidroksipropilceluloza (E463), hipromeloza (E464).
English: Investigations:
Slovenian: Preiskave
English: As with other drugs that block angiotensin II or its effects, concomitant use of other drugs which retain potassium (e.g. potassium-sparing diuretics: amiloride, triamterene, spironolactone) or may increase potassium levels (e.g. heparin), potassium supplements or salt substitutes containing potassium may lead to increases in serum potassium.
Slovenian: Kot pri drugih zdravilih, ki zavirajo angiotenzin II ali njegove učinke, lahko sočasna uporaba drugih zdravil, ki zadržujejo kalij (npr. diuretikov, ki varčujejo kalij, amilorida, triamterena, spironolaktona) ali lahko povečajo količino kalija (npr. heparin), dodatkov kalija ali nadomestkov soli, ki vsebujejo kalij, povzroči zvišanje vrednosti kalija v serumu.
English: As with other drugs that affect the renin-angiotensin-aldosterone system, increases in blood urea and serum creatinine have also been reported in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney; these changes in renal function may be reversible upon discontinuation of therapy.
Slovenian: Kot pri drugih zdravilih, ki vplivajo na renin-angiotenzinaldosteronski sistem, so poročali tudi o povišanju koncentracije sečnine v krvi in serumskega kreatinina pri bolnikih z bilateralno stenozo ledvične arterije ali stenozo ledvične arterije ob solitarni ledvici; te spremembe ledvične funkcije se po prekinitvi zdravljenja lahko povrnejo v predhodno stanje.
English: Hypertensive patients with left ventricular hypertrophy In a controlled clinical trial in hypertensive patients with left ventricular hypertrophy the following adverse events were reported:
Slovenian: Hipertenzivni bolniki s hipertrofijo levega prekata V kontroliranem kliničnem preizkušanju pri hipertenzivnih bolnikih s hipertrofijo levega prekata so poročali o naslednjih neželenih učinkih:
English: Aortic and mitral valve stenosis, obstructive hypertrophic cardiomyopathy As with other vasodilators, special caution is indicated in patients suffering from aortic or mitral stenosis, or obstructive hypertrophic cardiomyopathy.
Slovenian: Zožanje aortne in mitralne zaklopke, obstruktivna hipertrofična kardiomiopatija Tako kot pri drugih vazodilatatorjih je posebna previdnost indicirana pri bolnikih, ki imajo zožitev aortne ali mitralne zaklopke ali obstruktivno hipertofično kardiomiopatijo.
English: SPECIAL STORAGE CONDITIONS Store in the original bottle.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Shranjujte v originalni plastenki.
English: A package containing 35 tablets (21 pcs of 12.5 mg tablet and 14 pcs of the 50 mg tablet) or 28 tablets (21 pcs of 12.5 mg tablet and 7 pcs of the 50 mg tablet) is available in a PVC/PE/PVDC titration blister package.
Slovenian: Pakiranje po 35 tablet (enaindvajset 12,5 mg tablet in štirinajst 50 mg tablet) in 28 tablet (enaindvajset 12,5 mg tablet in sedem 50 mg tablet) je na voljo v PVC/PE/PVDC pretisnih omotih za titracijsko odmerjanje.
English: Treatment with losartan reduced the risk of stroke by 25% relative to atenolol (p=0.001 95% confidence interval 0.63-0.89).
Slovenian: Zdravljenje z losrtanom je v primerjavi z atenololom zmanjšalo tveganje za možgansko kap za 25 % (p=0,001 95-odstotni interval zaupanja 0,63-0,89).
English: Other substances inducing hypotension like tricyclic antidepressants, antipsychotics, baclofene, amifostine: Concomitant use with these drugs that lower blood pressure, as main or side-effect, may increase the risk of hypotension.
Slovenian: Druge učinkovine, ki povzročajo hipotenzijo, kot so triciklični antidepresivi, antipsihotiki, baklofen, amifostin: sočasna uporaba teh učinkovin, ki znižujejo krvni tlak (in je to njihov glavni ali neželeni učinek), lahko poveča tveganje za hipotenzijo.
English: In controlled clinical trials for essential hypertension with losartan the following adverse events were reported
Slovenian: V kontroliranih kliničnih preizkušanjih esencialne hipertenzije z uporabo losartana so poročali o naslednjih neželenih učinkih:
English: There is no therapeutic experience in patients with severe hepatic impairment.
Slovenian: Terapevtskih izkušenj pri bolnikih s hudo okvaro jeter nimamo.
English: In repeated dose toxicity studies, the administration of losartan induced a decrease in the red blood cell parameters (erythrocytes, haemoglobin, haematocrit), a rise in urea-N in the serum and occasional rises in serum creatinine, a decrease in heart weight (without a histological correlate) and gastrointestinal changes (mucous membrane lesions, ulcers, erosions, haemorrhages).
Slovenian: V študijah toksičnosti pri ponavljajočih se odmerkih je uporaba losartana povzročila zmanjšanje števila eritrocitov, hemoglobina, hematokrita, povečanje količine N-sečnine v serumu in občasno zvišanje kreatinina v serumu, zmanjšanje mase srca (brez histološke povezave) in spremembe v prebavilih (poškodbe, razjede, erozije in krvavitve mukozne membrane).
English: Following oral and intravenous administration of 14C-labeled losartan potassium, circulating plasma radioactivity primarily is attributed to losartan and its active metabolite.
Slovenian: Radioaktivnost plazme po peroralni in intravenski aplikaciji s 14C označenega losartana pripisujemo predvsem losartanu in njegovemu aktivnemu presnovku.
English: Renal transplantation There is no experience in patients with recent kidney transplantation.
Slovenian: Presaditev ledvice Izkušenj pri bolnikih z nedavno presaditvijo ledvice ni.
English: Mean peak concentrations of losartan and its active metabolite are reached in 1 hour and in 3-4 hours, respectively.
Slovenian: Najvišja srednja koncentracija losartana in njegovega aktivnega presnovka so dosežene po 1 oz. 3-4 urah.
English: - the scope of the referral was the harmonisation of the Summaries of Products Characteristics, labelling and package leaflet.
Slovenian: - Namen napotitve je bil usklajevanje povzetkov glavnih značilnosti zdravila, označevanja in navodila za uporabo.
English: The primary endpoint was the composite of cardiovascular morbidity and mortality as measured by a reduction in the combined incidence of cardiovascular death, stroke and myocardial infarction.
Slovenian: Primarni opazovani dogodek sta predstavljali srčno-žilna obolevnost in smrtnost, merjeni z zmanjšanjem kombinirane pojavnosti smrti zaradi srčno-žilnih zapletov, možganske kapi in miokardnega infarkta.
English: Galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorbtion Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucosegalactose malabsorption should not take this medicine.
Slovenian: Bolniki z redko dedno intoleranco za galaktozo, laponsko obliko zmanjšane aktivnosti laktaze ali malabsorpcijo glukoze-galaktoze tega zdravila ne smejo jemati.
English: The following side effects have been reported with Cozaar:
Slovenian: Poročali so o naslednjih neželenih učinkih zdravila Cozaar:
English: Cardiac disorder: Uncommon: palpitations, angina pectoris
Slovenian: Srčne bolezni občasne: palpitacije, angina pektoris
English: In controlled clinical trials for essential hypertension, hypertensive patients with left ventricular hypertrophy, chronic heart failure as well as for hypertension and type 2 diabetes mellitus with renal disease, the most common adverse event was dizziness.
Slovenian: V kontroliranih kliničnih preizkušanjih pri bolnikih z esencialno hipertenzijo, pri hipertenzivnih bolnikih z hipertrofijo levega prekata, pri bolnikih s kroničnim srčnim popuščanjem ter bolnikih s hipertenzijo in sladkorno boleznijo tipa 2 z boleznijo ledvic je bila najpogostejši neželeni učinek omotica.
English: Preclinical data reveal no special hazard for humans based on conventional studies of general pharmacology, genotoxicity and carcinogenic potential.
Slovenian: Predklinični podatki na osnovi običajnih študij splošne farmokologije, genotoksičnosti in kancerogenega potenciala ne kažejo posebnega tveganja za človeka.
English: The patients should have a left ventricular ejection fraction ≤ 40% and should be stabilised under the treatment of the chronic heart failure.
Slovenian: Bolniki morajo imeti iztisno frakcijo levega prekata ≤ 40 % in morajo biti stabilni ob zdravljenu kroničnega srčnega popuščanja.
English: Patients with proteinuria and a serum creatinine of 1.3 - 3.0 mg/dl were randomised to receive Losartan 50 mg once a day, titrated if necessary, to achieve blood pressure response, or to placebo, on a background of conventional antihypertensive therapy excluding ACE-inhibitors and angiotension II antagonists.
Slovenian: Bolnike s proteinurijo in vrednostjo kreatinina v serumu1,3-3,0 mg/dl so randomizirali tako, da so dobivali losartan 50 mg enkrat na dan (po potrebi so odmerek titrirali, da so dosegli odziv krvnega tlaka) ali placebo; poleg tega so bolniki iz obeh skupin dobivali običajna antihipertenzivna zdravila razen zaviralcev ACE in antagonistov angiotenzina II.
English: • medicines which retain potassium or may increase potassium levels (e.g. potassium supplements, potassium-containing salt substitutes or potassium-sparing medicines such as certain diuretics [amiloride, triamteren, spironolactone] or heparine),
Slovenian: • zdravila, ki zadržujejo kalij ali lahko povečajo količino kalija (npr. dodatki kalija, nadomestki soli, ki vsebujejo kalij, zdravila, ki varčujejo kalij, kot so določeni diuretiki [amilorid, trimateren, spironolakton], ali heparin).
English: • Treatment of chronic heart failure (in patients ≥ 60 years), when treatment with ACE inhibitors is not considered suitable due to incompatibility, especially cough, or contraindication.
Slovenian: • Zdravljenje kroničnega srčnega popuščanja (pri bolnikih ≥ 60 let) kadar zdravljenje z zaviralci ACE ne velja za primerno zaradi inkompatibilnosti, posebno kašlja, ali kontraindikacije.
English: • localised swelling (oedema).
Slovenian: • lokalizirano zatekanje (edem)
English: The use of losartan is not recommended during the first trimester of pregnancy (see section 4.4).
Slovenian: Uporaba losartana v prvem trimesečju nosečnosti ni priporočljiva (glejte poglavje 4.4).
English: PHARMACEUTICAL FORM AND CONTENTS 7, 14, 21, 28, 50, 98, 210 or 500 film-coated tablets.
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 7, 14, 21, 28, 50, 98, 210 ali 500 filmsko obloženih tablet.
English: There is no sufficient therapeutic experience with losartan in patients with heart failure and concomitant severe renal impairment, in patients with severe heart failure (NYHA class IV) as well as in patients with heart failure and symptomatic life threatening cardiac arrhythmias.
Slovenian: Izkušenj z zdravljenjem z losartanom pri bolnikih s srčnim popuščanjem in sočasno hudo okvaro ledvic, pri bolnikih s hudim srčnim popuščanjem (NYHA razred IV) ter bolnikih s srčnim popuščanjem in simptomatsko življenjsko nevarno srčno aritmijo ni dovolj.
English: Treatment usually starts with 50 mg losartan (one tablet Cozaar 50 mg) once a day.
Slovenian: Zdravljenje se običajno začne s 50 mg losartana (ena tableta Cozaar 50 mg) enkrat na dan.
English: In patients >50 kg, the usual dose is 50 mg once daily.
Slovenian: Pri bolnikih > 50 kg je običajni odmerek 50 mg enkrat na dan.
English: Hypertension Studies
Slovenian: Študije hipertenzije
English: There is no therapeutic experience with losartan in patients with severe hepatic impairment.
Slovenian: Izkušenj z zdravljenjem z losartanom pri bolnikih s hudo jetrno okvaro ni.
English: - Treatment of renal disease in patients with hypertension and type 2 diabetes mellitus with proteinuria > 0.5 g/day as part of an antihypertensive treatment
Slovenian: - Zdravljenje ledvične bolezni pri bolnikih s hipertenzijo in sladkorno boleznijo tipa 2 s proteinurijo > 0,5 g/dan kot del antihipertenzivnega zdravljenja
English: • to protect the kidney in hypertensive type 2 diabetic patients with laboratory evidence of impaired renal function and proteinuria ≥ 0.5 g per day (a condition in which urine contains an abnormal amount of protein).
Slovenian: • za zaščito ledvic pri bolnikih s hipertenzijo in sladkorno boleznijo tipa 2, pri katerih so laboratorijski izvidi pokazali okvaro ledvic in proteinurijo ≥ 0,5 g na dan (stanje s preveliko količino beljakovin v urinu).
English: Renal clearance of losartan and its active metabolite is about 74 mL/min and 26 mL/min, respectively.
Slovenian: Renalni očistek losartana je 74 ml/min, njegovega aktivnega presnovka pa 26 ml/min.
English: During administration of Losartan, removal of the angiotensin II negative feedback on renin secretion leads to increased plasma renin activity (PRA).
Slovenian: Med dajanjem losartana odsotnost negativne povratne zveze angiotenzina II na izločanje renina povzroči povečano aktivnost renina v plazmi.
English: 2003 PC HAARLEM the Netherlands
Slovenian: 2003 PC Haarlem Nizozemska
English: 2003 PC Haarlem The Netherlands
Slovenian: 2003 PC HAARLEM Nizozemska
English: The following wording has been added to SPC section 4.2 Posology and Method of Administration:
Slovenian: Naslednje besedilo je bilo dodano v poglavje 4.2 SPC „Odmerjanje in način uporabe“:
English: Concomitant use of losartan and ACE-inhibitors has shown to impair renal function.
Slovenian: Za sočasno uporabo losartana in zaviralcev ACE se je izkazalo, da poslabša ledvično funkcijo.
English: • to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower high blood pressure) is not considered suitable by your doctor.
Slovenian: • za zdravljenje bolnikov s kroničnim srčnim popuščanjem, če zdravnik meni, da zdravljenje z zaviralci angiotenzinske konvertaze (zaviralci ACE, zdravila za zniževanje krvnega tlaka) ni primerno.
English: In controlled clinical studies, once-daily administration of Losartan to patients with mild to moderate essential hypertension produced statistically significant reductions in systolic and diastolic blood pressure.
Slovenian: V kontroliranih kliničnih študijah je losartan v odmerkih enkrat na dan pri bolnikih z blago do zmerno esencialno hipertenzijo statistično pomembno znižal sistolični in diastolični krvni tlak.
English: Electrolyte imbalances are common in patients with renal impairment, with or without diabetes, and should be addressed.
Slovenian: Pri bolnikih z okvaro ledvic, s sladkorno boleznijo ali brez nje, so pogosta elektrolitska neravnovesja, ki jih je treba urediti.
English: if you suffer from excessive vomiting or diarrhoea leading to an extreme loss of fluid and/or salt in your body,
Slovenian: • če močno bruhate ali imate hudo drisko in zato izgubljate veliko tekočine in/ali soli.
English: PHARMACEUTICAL FORM AND CONTENTS 7 film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 7 filmsko obloženih tablet 28 filmsko obloženih tablet
English: Increase in the PRA leads to an increase in angiotensin II in plasma.
Slovenian: Povečana aktivnost renina v plazmi povzroči zvečanje koncentracije angiotenzina II v plazmi.
English: Belgium Therabel Pharma S.A. Rue Egide Van Ophem 108 B-1180 Brussels
Slovenian: Therabel Pharma S.A. - Rue Egide Van Ophem 108 - B-1180 Bruselj, Belgija