FrancophonIA/ELRC3.0 huggingface dataset:
English: According to current treatment guidelines, dual therapy with protease inhibitors is generally not recommended.
Danish: Proteasehæmmere: Ifølge nuværende retningslinjer frarådes kombinationsbehandling med flere proteasehæmmere.
English: Paroxetine: Cmax ↓ 51% Paroxetine: AUC ↓ 55%
Danish: Paroxetin: Cmax  51 % Paroxetin: AUC 55 %
English: Rifampicin 600 mg once daily
Danish: Rifampicin 600 mg én gang daglig
English: Don't stop Telzir without advice Take Telzir for as long as your doctor recommends.
Danish: Tag Telzir så længe som lægen har anbefalet.
English: Drugs by Therapeutic Area Interaction
Danish: Lægemidler efter terapeutisk område
English: AUC ↓ 55% (-76%; -16%) Cmin ↓ 36 % (-57%; -3%)
Danish: Cmax 51 % (-75 % til -3 %) AUC 55 % (-76 % til -16 %) Cmin 36 % (-57 % til -3 %)
English: Lopinavir / ritonavir
Danish: LPV/RTV - lopinavir / ritonavir.
English: ≤ 200 mg once daily
Danish: Methadon ≤ 200 mg én gang daglig
English: In a randomised open-label study (APV30003) in protease inhibitor experienced patients with virological failure (less than or equal to two PIs) the fosamprenavir with ritonavir combination (700 / 100 mg twice daily or 1400 / 200 mg once daily) did not demonstrate non-inferiority to lopinavir / ritonavir with regard to viral suppression as measured by the average area under the curve minus baseline (AAUCMB) for plasma HIV-1 RNA over 48 weeks (the primary end point).
Danish: I et randomiseret åbent studie (APV30003) med proteasehæmmer-erfarne patienter, som havde virologisk svigt (< 2 PI'er) viste kombinationen med fosamprenavir og ritonavir (700/100 mg 2 gange daglig eller 1.400/200 mg én gang daglig) ikke non-inferioritet over for lopinavir/ritonavir med hensyn til viral suppression målt ved det gennemsnitlige areal under kurven minus baseline (AAUCMB) for plasma hiv-1-RNA over 48 uger (det primære endepunkt).
English: Pink film coated, capsule shaped, biconvex tablets, marked with GXLL7 on one side.
Danish: De filmovertrukne tabletter er lyserøde, kapselformede og bikonvekse.
English: Amprenavir Cmax ↔ Amprenavir AUC ↔ Amprenavir Cmin (C12h) ↔
Danish: Amprenavir Cmax  Amprenavir AUC  Amprenavir Cmin (C12h)  (Forhøjet gastrisk pH)
English: Fosamprenavir with ritonavir was generally well-tolerated in subjects with mild, moderate, or severe hepatic impairment, and these regimens had similar adverse event and clinical laboratory profiles as previous studies of HIV-1 infected subjects with normal hepatic function.
Danish: Ovennævnte studier viste samme bivirkningsprofil og samme kliniske laboratorieværdier som tidligere studier af hiv-1-inficerede personer med normal leverfunktion.
English: Push the plastic adapter into the neck of the bottle, while holding the bottle firmly.
Danish: Hold fast om flasken og sæt plastikadaptoren i flaskehalsen.
English: Subjects (%) with plasma HIV-1 RNA <50 copies/ml
Danish: Patienter (%) med plasma-hiv1-RNA < 50 kopier/ml
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON FOR TABLETS
Danish: YDRE KARTON TIL TABLETTER
English: ViiV Healthcare SAS Tél: + 33 (0)1 39 17 6969 Infomed@viivhealthcare.com
Danish: : + 33 (0)1 39 17 6969 Infomed@viivhealthcare.com
English: In subjects with severe hepatic impairment (Child-Pugh score of 10-13), a reduced dose of fosamprenavir 300 mg twice daily with a reduced dosing frequency of ritonavir 100 mg once daily delivered 19% lower plasma amprenavir Cmax, 23% lower AUC(0-12), and 38% lower C12 values, but similar unbound plasma amprenavir C12 values than achieved in subjects with normal hepatic function receiving the standard fosamprenavir with ritonavir 700 mg / 100 mg twice daily regimen.
Danish: Hos personer med svært nedsat leverfunktion (Child-Pugh score på 10-13) medførte en reduceret dosis af fosamprenavir på 300 mg 2 gange daglig i kombination med 100 mg ritonavir reduceret til én gang daglig en 19 % lavere plasma-Cmax, 23 % lavere plasma-AUC(0-12) og 38 % lavere plasma-C12værdier for amprenavir end hos personer med normal leverfunktion, som fik standardbehandlingen 700 mg fosamprenavir i kombination med 100 mg ritonavir 2 gange daglig.
English: amprenavir and raltegravir (especially in fed conditions) may result in virological
Danish: Signifikant nedsat eksposition og Cmin er observeret for både amprenavir og raltegravir (især ved samtidig fødeindtagelse), hvilket kan medføre virologisk svigt hos nogle patienter.
English: Do not leave the syringe in the bottle.
Danish: 10. Sprøjten må ikke efterlades i flasken efter brug.
English: For adults with moderate hepatic impairment (Child-Pugh score: 7-9) the recommended dose is 450 mg fosamprenavir (i.e. 9 ml Telzir oral suspension) twice daily with 100 mg ritonavir once daily.
Danish: Til voksne med moderat nedsat leverfunktion (Child-Pugh Score: 7-9) er den anbefalede dosis 450 mg fosamprenavir (f.eks. 9 ml Telzir oral suspension) 2 gange daglig i kombination med 100 mg ritonavir en gang daglig.
English: 150 mg every other day
Danish: Rifabutin 150 mg hver anden dag
English: If you take too much Telzir
Danish: Hvis du holder op med at tage Telzir
English: For adult patients the fosamprenavir oral suspension should be taken without food and on an empty stomach.
Danish: Voksne patienter bør tage fosamprenavir oral suspension uden mad og på tom mave.
English: LPV/RTV 400 mg/100 mg BID (n=91)
Danish: LPV/RTV 400 mg/100 mg 2 gange daglig (n=91)
English: Subjects (%) with plasma HIV-1 RNA <400 copies/ml
Danish: Patienter (%) med plasma-hiv1-RNA < 400 kopier/ml
English: HMG-COA REDUCTASE INHIBITORS
Danish: HMG-COAREDUKTASEHÆMMERE
English: • The other ingredients are: hypromellose, sucralose, polysorbate 80, calcium chloride dihydrate,
Danish: • Øvrige indholdsstoffer: hypromellose, sucralose, polysorbat 80, calciumchloriddihydrat, syntetisk grape-tyggegummismagsstof, naturligt pebermyntesmagsstof, renset vand, propylenglycol, methylparahydroxybenzoat (E218) og propylparahydroxybenzoat (E216).
English: Each ml of suspension contains 50 mg of fosamprenavir as fosamprenavir calcium salt (equivalent to approximately 43 mg of amprenavir).
Danish: Hver ml af suspensionen indeholder 50 mg fosamprenavir som fosamprenavircalciumsalt (svarende til ca. 43 mg amprenavir).
English: 400 mg/100 mg twice daily
Danish: Lopinavir / ritonavir 400 mg/100 mg 2 gange daglig
English: Atazanavir: Cmax ↓ 24%* Atazanavir: AUC ↓ 22%* Atazanavir: Cmin↔* *compared to atazanavir/ ritonavir 300 mg/ 100 mg once daily
Danish: Atazanavir: Cmax  24 %* Atazanavir: AUC 22 %* Atazanavir: Cmin* *sammenlignet med atazanavir/ ritonavir 300 mg/ 100 mg én gang daglig
English: All Subjects Baseline HIV-1 RNA < 100,000 copies/ml
Danish: Baseline-hiv-1-RNA < 100.000 kopier/ml
English: Doses of atorvastatin no greater than 20 mg/day should be administered, with careful monitoring for atorvastatin toxicity.
Danish: Atorvastatindoser op til 20 mg/dag kan administreres.
English: GlaxoSmithKline s.r.o.
Danish: Česká republika GlaxoSmithKline s.r.o.
English: Each tablet contains 700 mg of fosamprenavir as fosamprenavir calcium (equivalent to approximately 600 mg amprenavir).
Danish: Hver tablet indeholder 700 mg fosamprenavir som fosamprenavircalcium (svarende til cirka 600 mg amprenavir).
English: Adults The recommended dose is one 700 mg Telzir tablet twice daily with 100 mg ritonavir twice daily.
Danish: Den sædvanlige dosis er én 700 mg Telzir tablet 2 gange daglig sammen med 100 mg ritonavir 2 gange daglig.
English: LPV/RTV 400 mg/100 mg BID (n=444)
Danish: LPV/RTV 400 mg/100 mg 2 gange daglig (n = 444)
English: In the paediatric studies APV20003 and APV29005, 77 PI-experienced patients were treated with fosamprenavir / ritonavir-based regimens and 43 patients met study-defined virologic failure criteria through 48 weeks in APV29005 and up to 108 weeks in APV20003.
Danish: 43 patienter mødte studiedefinerede virologiske fejlkriterier gennem 48 uger i APV29005 og op til 108 uger i APV20003.
English: If you have moderate liver disease the dose is 9 ml Telzir oral suspension (450 mg fosamprenavir) twice daily with 100 mg ritonavir only once daily.
Danish: Hvis du har en moderat leversygdom, er dosis 9 ml Telzir oral suspension (450 mg fosamprenavir) 2 gange daglig med 100 mg ritonavir kun én gang daglig.
English: Oral suspension should be taken with food <25 kg No dosing recommendations
Danish: < 25 kg Ingen doseringsanbefalinger
English: Adults should take Telzir oral suspension without food and on an empty stomach.
Danish: Voksne bør tage Telzir oral suspension uden samtidig indtagelse af mad og på tom mave.
English: In the studies of PI-experienced adult patients, PRO30017 (amprenavir 600 mg / ritonavir 100 mg twice daily in sub-study A and B with 80 and 37 patients respectively), the following mutations emerged in patients with virological failure: L10F/I/V, V11I, I13V, K20R, V32I, L33F, E34Q, M36I, M46I/L, I47V, G48V, I50V, I54L/M/T/V, Q58E, D60E, I62V, A71V, V77I, V82A/I, I84V, I85V, L90M and I93L/M.
Danish: I forbindelse med studier af voksne patienter, som fik behandling med PI'er, observeredes følgende mutationer hos de patienter, der fik virologisk svigt: L10F/I/V, V11I, I13V, K20R, V32I, L33F, E34Q, M36I, M46I/L, I47V, G48V, I50V, I54L/M/T/V, Q58E, D60E, I62V, A71V, V77I, V82A/I, I84V, I85V, L90M og I93L/M.
English: Amiodarone: ↑ expected Bepridil: ↑ expected Quinidine: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Amiodaron:  forventet Bepridil:  forventet Quinidin:  forventet (FPV/RTV hæmmer CYP3A4)
English: If you have mild liver disease, the dose is one Telzir tablet (700 mg) twice daily with 100 mg ritonavir only once daily.
Danish: Hvis du har en mild leversygdom, er den sædvanlige dosis én Telzir tablet (700 mg) 2 gange daglig med 100 mg ritonavir kun én gang daglig.
English: FPV/RTV 700 mg/100 mg BID (n= 434)
Danish: FPV/RTV 700 mg/100 mg 2 gange daglig (n = 434)
English: For adults with mild hepatic impairment (Child-Pugh score: 5-6) the recommended dose is 700 mg fosamprenavir twice daily with 100 mg ritonavir once daily.
Danish: Til voksne med let nedsat leverfunktion (Child-Pugh Score: 5-6) er den anbefalede dosis 700 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir en gang daglig.
English: Telzir/ritonavir should not be co-administered with orally administered midazolam (see section 4.3), whereas caution should be used with co-administration of Telzir/ritonavir and parenteral midazolam.
Danish: Der skal udvises forsigtighed ved samtidig administration af Telzir/ritonavir og parenteral midazolam.
English: Caution is advised if the recommended dose of fosamprenavir with ritonavir detailed below are exceeded (see section 4.4).
Danish: Forsigtighed tilrådes ved doser, der er større end de anbefalede (se pkt.
English: Children and adolescents: The adverse reaction profile in children and adolescents is based on integrated safety data from two studies (APV29005 Week 24 data and APV20003 Week 168 data [final data]) in which 158 HIV-1 infected subjects 2 to 18 years of age received fosamprenavir with ritonavir with background nucleoside reverse transcriptase inhibitor therapy (see section 5.1 for information on dosing regimens applied for each age group).
Danish: Børn og unge: Bivirkningsprofilen hos børn og unge er baseret på integrerede sikkerhedsdata fra to studier (APV29005 uge 24 data og APV20003 uge 168 data [endelige data]).
English: What Telzir is and what it is used for What you need to know before you take Telzir How to take Telzir
Danish: Det skal du vide, før du begynder at tage Telzir Sådan skal du tage Telzir Bivirkninger
English: Didanosine gastro-resistant capsule
Danish: Didanosin-enterokapsel
English: Ethinyl estradiol: Cmax Ethinyl estradiol: AUC
Danish: Ethinylestradiol: Cmax 28 % Ethinylestradiol: AUC 37 %
English: Each film-coated tablet contains 700 mg fosamprenavir as fosamprenavir calcium (equivalent to approximately 600 mg of amprenavir)
Danish: Hver filmovertrukken tablet indeholder 700 mg fosamprenavir som fosamprenavircalcium (svarende til ca. 600 mg amprenavir)
English: Harmire Road Barnard Castle Co. Durham DL12 8DT United Kingdom
Danish: Co. Durham DL12 8DT Storbritannien eller
English: For adults with moderate hepatic impairment (Child-Pugh score: 7-9) the recommended dose is 450 mg fosamprenavir twice daily with 100 mg ritonavir once daily.
Danish: Til voksne med moderat nedsat leverfunktion (Child-Pugh Score: 7-9) er den anbefalede dosis 450 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir en gang daglig.
English: b) PI-experienced patients
Danish: b) Patienter, der tidligere har været behandlet med PI'er Amprenavir
English: Fluticasone propionate: ↑ Intrinsic cortisol levels: ↓
Danish: Intrinsisk kortisolniveau: 
English: 1000 - 10,000 copies/ml >10,000 - 100,000 copies/ml >100,000 copies/ml AAUCMB Observed Analysis
Danish: 1.000 - 10.000 kopier/ml
English: Medicinal products - interactions
Danish: LÆGEMIDLER MOD INFEKTIONER
English: If you have severe liver disease the dose is 6 ml Telzir oral suspension (300 mg fosamprenavir) twice daily with 100 mg ritonavir only once daily.
Danish: Hvis du har en svær leversygdom, er dosis 6 ml Telzir oral suspension (300 mg fosamprenavir) 2 gange daglig med 100 mg ritonavir kun én gang daglig.
English: In a clinical study on pharmacokinetics of fosamprenavir in paediatric patients, eight subjects 12 to 18 years of age received the standard fosamprenavir adult tablet dose of 700 mg twice daily (with ritonavir 100 mg twice daily).
Danish: Otte patienter mellem 12 og 18 år blev behandlet med tabletstandarddoseringen til behandling af voksne på 700 mg fosamprenavir 2 gange daglig (i kombination med 100 mg ritonavir 2 gange daglig).
English: In adults, the oral suspension should be taken without food and on an empty stomach.
Danish: Voksne bør tage den orale suspension uden mad og på tom mave.
English: Amprenavir: AUC ↓ 82% Contraindicated (see section
Danish: Amprenavir: AUC  82 %
English: Propafenone: ↑ expected (CYP2D6 inhibition by RTV)
Danish: Flecainid:  forventet Propafenon:  forventet (RTV hæmmer CYP2D6)
English: (Mild CYP2D6 inhibition by RTV)
Danish: (RTV hæmmer i mindre grad CYP2D6)
English: Norethisterone: Cmax ↓ 38% Norethisterone: AUC ↓ 34% Norethisterone: Cmin ↓ 26
Danish: Norethisteron: Cmax 38 % Norethisteron: AUC 34 % Norethisteron: Cmin  26 % (FPV/RTV inducerer CYP3A4)
English: Combination of rifampicin with Telzir with concomitant low-dose ritonavir is contraindicated (see section 4.5).
Danish: Samtidig behandling med Telzir og lavdosis ritonavir i kombination med rifampicin er kontraindiceret (se pkt.
English: Hepatitis C virus (HCV) Direct-Acting Antivirals: When hepatitis C virus direct-acting antiviral (DAA) drugs, which are metabolised by CYP3A4 or are inducers/inhibitors of CYP3A4, are coadministered with fosamprenavir/ritonavir, altered plasma concentrations of medications are expected due to inhibition or induction of CYP3A4 enzyme activity (see sections 4.3 and 4.5).
Danish: Hepatitis C-virus (HCV) direkte virkende antivirale stoffer: Når hepatitis C-virus direkte virkende antivirale stoffer, som metaboliseres af CYP3A4, eller som er induktorer/hæmmere af CYP3A4,
English: If you have mild liver disease, the dose is 14 ml Telzir oral suspension (700 mg fosamprenavir) twice daily with 100 mg ritonavir only once daily.
Danish: Hvis du har en mild leversygdom, er dosis 14 ml Telzir oral suspension (700 mg fosamprenavir) 2 gange daglig med 100 mg ritonavir kun én gang daglig.
English: A MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE Name and address of the manufacturers responsible for batch release Film-coated tablets
Danish: Navn og adresse på den fremstiller, der er ansvarlig for batchfrigivelse
English: ombitasvir +/- dasabuvir suggest that coadministration of fosamprenavir/ritonavir with paritaprevir/ritonavir/ ombitasvir+/-dasabuvir is likely to lead to increased plasma exposures of paritaprevir due to CYP3A4 enzyme inhibition and higher ritonavir dose.
Danish: Resultater fra studier med andre hiv-proteasehæmmere og paritaprevir/ritonavir/ombitasvir +/- dasabuvir antyder, at samtidig administration af fosamprenavir/ritonavir og paritaprevir/ritonavir/ombitasvir +/- dasabuvir sandsynligvis medfører øget plasmakoncentration af paritaprevir pga. CYP3A4enzymhæmning og højere ritonavir-dosis.
English: ≥ 4 mutations from score
Danish: Resistente over for FPV/RTV ≥ 4 mutationer fra score
English: Vardenafil
Danish: Terfenadin
English: ANTIARRHYTHMICS
Danish: ANTIPSYKOTIKA
English: Each ml of oral suspension contains 50 mg fosamprenavir as fosamprenavir calcium (equivalent to approximately 43 mg amprenavir).
Danish: En ml oral suspension indeholder 50 mg fosamprenavir som fosamprenavircalcium (svarende til ca. 43 mg amprenavir).
English: Not recommended.
Danish: Frarådes.
English: Antiretroviral Experienced Adult Patients
Danish: Voksne patienter tidligere behandlet med antiretrovirale lægemidler
English: Each ml of oral suspension contains 50 mg fosamprenavir as fosamprenavir calcium (equivalent to approximately 43 mg of amprenavir)
Danish: En ml oral suspension indeholder 50 mg fosamprenavir som fosamprenavircalcium (svarende til ca. 43 mg amprenavir)
English: (CYP3A4 induction by FPV/RTV)
Danish: (FPV/RTV inducerer CYP3A4)
English: ANNEX III LABELLING AND PACKAGE LEAFLET
Danish: Oversigt over indlægssedlen Virkning og anvendelse
English: Children from 6 years of age and weighing at least 39 kg Children can take the adult tablet dose of one 700 mg Telzir tablet twice daily with ritonavir 100 mg twice daily if they can swallow the tablets whole.
Danish: Børn kan tage en voksendosis på én 700 mg Telzir tablet 2 gange daglig sammen med 100 mg ritonavir 2 gange daglig, hvis de kan sluge tabletterne hele.
English: Potential for increased
Danish: Integrasehæmmere
English: In the studies of PI-experienced adult patients, APV30003 and its extension, APV30005 (fosamprenavir 700 mg / ritonavir 100 mg twice daily: n=107), the following mutations emerged in patients experiencing virological failure through 96 weeks: L10F/I, L24I, V32I, L33F, M36I, M46I/L, I47V, I50V, I54L/M/S, A71I/T/V, G73S, V82A, I84V, and L90M.
Danish: Følgende mutationer blev påvist hos de patienter, der fik virologsik svigt i løbet af 96 uger: L10F/I, L24I, V32I, L33F, M36I, M46I/L, I47V, I50V, I54L/M/S, A71I/T/V, G73S, V82A, I84V og L90M.
English: Itraconazole: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Itraconazol:  forventet (FPV/RTV hæmmer CYP3A4)
English: In subjects with moderate hepatic impairment (Child-Pugh score of 7-9), a reduced dose of fosamprenavir 450 mg twice daily with a reduced dosing frequency of ritonavir 100 mg once daily is predicted to deliver similar plasma amprenavir Cmax and AUC(0-12), but approximately 35 % lower plasma total amprenavir C12 values and approximately 88 % higher plasma unbound amprenavir C12 values than achieved in subjects with normal hepatic function receiving the standard fosamprenavir with ritonavir 700 mg / 100 mg twice daily regimen.
Danish: Hos personerne med moderat nedsat leverfunktion (Child-Pugh score på 7-9) forventes en reduceret dosis af fosamprenavir på 450 mg 2 gange daglig i kombination med 100 mg ritonavir reduceret til én gang daglig at give samme plasma-Cmax and plasma-AUC(0-12) for amprenavir, som dem, der blev opnået hos personer med normal leverfunktion og som fik administreret 700 mg fosamprenavir 2 gange daglig i kombination med 100 mg ritonavir 2 gange daglig.
English: Don't push too hard and squirt the liquid into the back of the throat or you may choke.
Danish: For kraftig sprøjten bagtil i halsen kan øge risikoen for, at du får væsken galt i halsen.
English: The mutational profiles were similar to those described for PIexperienced adults treated with fosamprenavir / ritonavir.
Danish: De nævnte mutationer sås kun sjældent, når ART-naive voksne patienter blev behandlet med de på nuværende tidspunkt godkendte doser af fosamprenavir/ritonavir.
English: In subjects with mild hepatic impairment (Child-Pugh score of 5-6), the dosage regimen of fosamprenavir 700 mg twice daily with a reduced dosing frequency of ritonavir 100 mg once daily provided slightly higher plasma amprenavir Cmax (17 %), slightly higher plasma amprenavir AUC(0-12) (22 %), similar plasma total amprenavir C12 values and approximately 117 % higher plasma unbound amprenavir C12 values compared to subjects with normal hepatic function receiving the standard fosamprenavir / ritonavir 700 mg /100 mg twice daily regimen.
Danish: Hos personerne med let nedsat leverfunktion sås en let forhøjet plasma-Cmax for amprenavir (17 %), en let forhøjet plasma-AUC(0-12) for amprenavir (22 %), tilsvarende totale plasma-C12-værdier for amprenavir og cirka 117 % højere plasma-C12-værdier for ubundet amprenavir.
English: • Feeling tired
Danish: • træthed
English: Blood cholesterol increased Blood triglycerides increased Alanine aminotransferase increased
Danish: Forhøjet kolesterol i blodet
English: Haemophiliacs may bleed more
Danish: Blødere kan bløde mere
English: After multiple dose oral administration of equivalent fosamprenavir and amprenavir doses, comparable amprenavir AUC values were observed; however, Cmax values were approximately 30 % lower and Cmin values were approximately 28 % higher with fosamprenavir.
Danish: For fosamprenavir var Cmax-værdien ca. 30 % lavere og Cmin-værdien ca. 28 % højere.
English: PDE5 inhibitors: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: PDE5-hæmmere:  forventet (FPV/RTV hæmmer CYP3A4)
English: Lidocaine: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Lidocain:  forventet (FPV/RTV hæmmer CYP3A4)
English: (CYP3A4 inhibition by FPV/RTV)
Danish: (FPV/RTV hæmmer CYP3A4)
English: Anti-fungals:
Danish: Antimykotika:
English: Uncommon side effects
Danish: Tabel over bivirkninger
English: NEUROLEPTIC Pimozide
Danish: NEUROLEPTIKA
English: • Feeling sick or being sick (nausea or vomiting), pain in the stomach, loose stools
Danish: Kvalme eller opkastning, mavesmerter, løs afføring
English: Pimozide: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Pimozid:  forventet (FPV/RTV hæmmer CYP3A4)
English: Erythromycin: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Erythromycin:  forventet (FPV/RTV hæmmer CYP3A4)
English: Liver disease
Danish: Leversygdomme
English: Halofantrine: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Halofantrin:  forventet (FPV/RTV hæmmer CYP3A4)
English: You may experience muscle problems
Danish: Muskelproblemer
English: • If you have haemophilia.
Danish: • hvis du lider af hæmofili (blødersygdom).
English: The relevance of the hepatocellular findings in the rodents for humans is uncertain; however, there is no evidence from clinical trials or marketed use to suggest that these findings are of clinical significance.
Danish: Der er dog ingen kliniske studier eller postmarketingsdata, der tyder på, at disse hepatocellulære fund har klinisk betydning.
English: Abacavir
Danish: Halofantrin
English: Cisapride: ↑ expected (CYP3A4 inhibition by FPV/RTV)
Danish: Cisaprid:  forventet (FPV/RTV hæmmer CYP3A4)
English: Children 6 to 11 years of age (n=9) receiving fosamprenavir / ritonavir 18 / 3 mg/kg twice daily had 26 % higher AUC(0-24) and similar Cmax and Cmin values when compared to the historical adult population receiving fosamprenavir / ritonavir 700 / 100 mg twice daily.
Danish: Børn i aldersgruppen 6 til 11 år (n=9) blev behandlet med 18 mg fosamprenavir/kg og 3 mg ritonavir/kg 2 gange daglig.
English: I62V, V82A/C/F/G, I84V and L90M and is associated with increased phenotypic resistance to fosamprenavir with ritonavir as well as reduced likelihood of virological response (resistance).
Danish: Den er forbundet med øget fænotyperesistens over for fosamprenavir i kombination med ritonavir samt som reduceret sandsynlighed for virologisk respons (resistens).
English: ERGOT DERIVATIVES
Danish: Bivirkninger
English: In heavily pretreated patients the use of Telzir in combination with low dose ritonavir has not been sufficiently studied.
Danish: Telzir i kombination med en lav dosis ritonavir er ikke tilstrækkeligt undersøgt hos patienter, der har fået antiretroviral behandling i en længere periode.
English: methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216).
Danish: Propylparahydroxybenzoat (E216)
English: ANTICONVULSANTS Phenytoin
Danish: Didanosin-tyggetablet