FrancophonIA/ELRC3.0 huggingface dataset:
English: You may take Neulasta out of the refrigerator and keep it at room temperature (not above 30°C) for no longer than 3 days.
Slovenian: Zdravilo Neulasta smete vzeti iz hladilnika in ga hraniti pri sobni temperaturi (pod 30 °C) največ 3 dni dolgo.
English: Patients with a recent history of pulmonary infiltrates or pneumonia may be at higher risk (see section 4.8).
Slovenian: Bolj ogroženi so lahko bolniki z nedavno anamnezo pljučnih infiltratov ali pljučnice (glejte poglavje 4.8).
English: If the pre-filled syringe co-packed with the on-body injector is used for manually administering a subcutaneous injection, the patient will receive more than the recommended dose.
Slovenian: Če je napolnjena injekcijska brizga, ki je priložena v pakiranju injektorja, uporabljena za ročno subkutano injiciranje, bolnik prejme večji odmerek od priporočenega.
English: - The active substance is pegfilgrastim.
Slovenian: - Učinkovina je pegfilgrastim.
English: Once filled, the on-body injector should be used for immediate application and can be applied on the same day as the administration of cytotoxic chemotherapy, as long as application is timed to ensure the on-body injector delivers Neulasta at least 24 hours after administration of cytotoxic chemotherapy.
Slovenian: Ko je injektor napolnjen, ga je treba namestiti takoj; namestiti ga je mogoče isti dan, ko je uporabljena citotoksična kemoterapija, pod pogojem, da injektor zdravilo Neulasta injicira vsaj 24 ur po uporabi citotoksične kemoterapije.
English: “BEEPS”
Slovenian: “PISKI”
English: Contact your healthcare provider immediately if the on-body injector comes away from your skin at any time before your full dose has been delivered.
Slovenian: Nemudoma se posvetujte z zdravnikom, če se vam telesni injektor odlepi od kože kadar koli prej, preden dobite celoten odmerek.
English: Hypersensitivity-type reactions, including skin rash, urticaria, angioedema, dyspnoea, erythaema, flushing, and hypotension occurred on initial or subsequent treatment with pegfilgrastim (uncommon [≥ 1/1,000 to < 1/100]).
Slovenian: Med začetnim ali nadaljnjim zdravljenjem s pegfilgrastimom so se pojavile reakcije preobčutljivostne vrste, vključno z izpuščajem na koži, urtikarijo, angioedemom, dispnejo, eritemom, zardevanjem in hipotenzijo (občasno [≥ 1/1.000 do < 1/100]).
English: • if you have sudden signs of allergy such as rash, itching or hives on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing these could be signs of a severe allergic reaction.
Slovenian: • če se vam pojavijo nenadni znaki alergije, kot so izpuščaj, srbečica ali koprivnica na koži, otekanje obraza, ustnic, jezika ali drugih delov telesa, kratka sapa, piskajoče ali oteženo dihanje.
English: Severe skin reactions (Stevens-Johnson syndrome) have been reported with the use of Neulasta.
Slovenian: Ob uporabi zdravila Neulasta so poročali o hudih kožnih reakcijah (Stevens-Johnsonov sindrom).
English: Correct
Slovenian: Pravilno
English: • Contact your healthcare provider immediately if you experience persistent or worsening redness or tenderness at the application site, as this can be a sign of infection.
Slovenian: • Nemudoma se posvetujte z zdravnikom, če pordelost ali občutljivost na mestu namestitve traja ali se slabša, kajti to je lahko znak okužbe.
English: • Contact your healthcare provider immediately as you may not have received your full dose and may need a replacement dose.
Slovenian: • Nemudoma se posvetujte z zdravnikom, ker morda niste dobili celotnega odmerka zdravila in boste morda potrebovali nadomestni odmerek.
English: Concomitant use of Neulasta with any chemotherapy agent has not been evaluated in patients.
Slovenian: Sočasne uporabe zdravila Neulasta s katerim koli kemoterapevtskim zdravilom pri bolnikih niso ovrednotili.
English: Splenomegaly, generally asymptomatic, is uncommon.
Slovenian: Občasen neželen učinek je splenomegalija, praviloma asimptomatska.
English: Pegfilgrastim appears to be mainly eliminated by neutrophil mediated clearance, which becomes saturated at higher doses.
Slovenian: Zdi se, da se pegfilgrastim izloča iz telesa v glavnem z očistkom, ki ga sprožijo nevtrofilci in ki se pri večjih odmerkih nasiti.
English: • If medicine has leaked or the adhesive is noticeably wet (saturated), contact your healthcare provider immediately as you may not have received your full dose and you may need a replacement dose.
Slovenian: • Če je zdravilo puščalo ali je lepilo opazno mokro (prepojeno), se nemudoma posvetujte z zdravnikom, saj morda niste dobili celotnega odmerka zdravila in boste morda potrebovali nadomestni odmerek.
English: • redness at the site of injection.
Slovenian: • pordelost na mestu injiciranja.
English: In one study (n = 157), which used a 6 mg fixed dose of pegfilgrastim the mean duration of grade 4 neutropenia for the pegfilgrastim group was 1.8 days compared with 1.6 days in the filgrastim group (difference 0.23 days, 95% CI -0.15, 0.63).
Slovenian: V eni študiji (n = 157), v kateri so uporabili stalni odmerek 6 mg pegfilgrastima, je bilo srednje trajanje nevtropenije 4. stopnje v skupini s pegfilgrastimom 1,8 dni, v skupini s filgrastimom pa 1,6 dni (razlika 0,23 dneva, 95 % IZ je -0,15, 0,63).
English: NL-4817 ZK Breda The Netherlands
Slovenian: NL-4817 ZK Breda Nizozemska
English: In a phase I (n = 253) randomised, single dose, parallel-group study conducted in healthy subjects the exposure (mean serum concentration-time profiles) of pegfilgrastim delivered by manual injection and by the on-body injector were comparable.
Slovenian: V randomizirani študiji I. faze vzporednih skupin z enim odmerkom (n = 253) pri zdravih osebah je bila izpostavljenost (profil povprečne serumske koncentracije skozi čas) pegfilgrastimu po ročnem injiciranju in injiciranju z injektorjem podobna.
English: Before use, Neulasta solution should be inspected visually for particulate matter.
Slovenian: Pred uporabo morate raztopino zdravila Neulasta pregledati glede vidnih delcev.
English: Regular monitoring of platelet count and haematocrit is recommended.
Slovenian: Priporočajo redno spremljanje števila trombocitov in hematokrita.
English: Increased haematopoietic activity of the bone marrow in response to growth factor therapy has been associated with transient positive bone-imaging findings.
Slovenian: Povečana hemopoetična aktivnost kostnega mozga zaradi zdravljenja z rastnimi dejavniki je bila povezana s prehodnimi pozitivnimi izvidi pri slikanju kosti, kar je treba upoštevati pri interpretaciji izvidov na podlagi slikanja kosti.
English: The needle cap on the pre-filled syringe contains a derivative of latex and may cause severe allergic reactions.
Slovenian: Pokrovček igle na napolnjeni injekcijski brizgi vsebuje derivat lateksa in lahko povzroči hude alergijske reakcije.
English: If the adhesive becomes noticeably wet (saturated) with fluid, or you see dripping, contact your healthcare provider immediately as you may need a replacement dose.
Slovenian: Če postane lepilo opazno mokro (napojeno) s tekočino, ali če opazite kapljanje, se nemudoma posvetujte z zdravnikom, kajti morda boste potrebovali nadomestni odmerek.
English: • Tell your doctor if you have an allergy to latex.
Slovenian: • Zdravniku morate povedati, če imate alergijo na lateks.
English: Contact dermatitis and local skin reactions such as rash, pruritus, and urticaria have been reported with the use of the on-body injector, possibly indicating a hypersensitivity reaction to the adhesive.
Slovenian: Med uporabo injektorja so poročali o kontaktnem dermatitisu in lokalnih kožnih reakcijah, kot so izpuščaj, srbenje in urtikarija, ki morda kažejo na preobčutljivostno reakcijo na lepilo.
English: Guide to parts for on-body injector for Neulasta Green flashing status light
Slovenian: Vodnik o delih injektorja za zdravilo Neulasta Zelena utripajoča lučka stanja
English: Uncommon pulmonary adverse reactions including interstitial pneumonia, pulmonary oedema, pulmonary infiltrates and pulmonary fibrosis have been reported.
Slovenian: Občasno so poročali o pljučnih neželenih reakcijah, vključno z intersticijsko pljučnico, pljučnim edemom, pljučnimi infiltrati in pljučno fibrozo.
English: Stop using Neulasta if you develop these symptoms and contact your doctor or seek medical attention immediately.
Slovenian: Če se vam pojavijo ti simptomi, prenehajte uporabljati zdravilo Neulasta in se nemudoma posvetujte z zdravnikom ali poiščite zdravniško pomoč.
English: Disposing of used syringes
Slovenian: Odlaganje rabljenih injekcijskih brizg
English: In a second study (n = 310), which used a weightadjusted dose (100 mcg/kg), the mean duration of grade 4 neutropenia for the pegfilgrastim group was 1.7 days, compared with 1.8 days in the filgrastim group (difference 0.03 days, 95% CI -0.36, 0.30).
Slovenian: V drugi študiji (n = 310), v kateri so uporabljali za telesno maso popravljen odmerek (100 μg/kg), je bilo srednje trajanje nevtropenije 4. stopnje v skupini s pegfilgrastimom 1,7 dni, v skupini s filgrastimom pa 1,8 dni (razlika 0,03 dneva, 95 % IZ je -0,36, 0,30).
English: The rate (Cmax) and extent (AUC0-inf) of the absorption of pegfilgrastim delivered by the on-body injector were similar to those from the manual injection of the pre-filled syringe.
Slovenian: Delež (Cmax) in obseg (AUC0-inf) absorpcije pegfilgrastima sta bila po injiciranju z injektorjem podobna kot po ročnem injiciranju z napolnjeno injekcijsko brizgo.
English: A Record the end status of your on-body injector.
Slovenian: A Zabeležite končno stanje injektorja.
English: What if my application site is red or tender after on-body injector removal?
Slovenian: Kaj če je mesto injiciranje po odstranitvi injektorja rdeče ali občutljivo?
English: The incidence of hospitalisations and IV anti-infective use associated with a clinical diagnosis of febrile neutropenia was lower in the pegfilgrastim group compared with placebo (1% versus 14%, p < 0.001; and 2% versus 10%, p < 0.001).
Slovenian: Med prejemnicami pegfilgrastima je bila tudi manjša incidenca hospitalizacij in intravensko uporabljene antiinfektivne terapije, povezanih s klinično diagnozo febrilne nevtropenije, kot med prejemnicami placeba (1 % v primerjavi s 14 %, p < 0,001, ter 2 % v primerjavi z 10 %, p < 0,001).
English: You may notice a small air bubble in the pre-filled syringe.
Slovenian: V napolnjeni injekcijski brizgi lahko opazite majhen zračni mehurček.
English: 6.6 Special precautions for disposal and other handling
Slovenian: 6.6 Posebni varnostni ukrepi za odstranjevanje
English: • Remove any extra adhesive using soap and water.
Slovenian: • Morebiten preostanek lepila odstranite z milom in vodo.
English: The on-body injector will use sounds and lights to let you know its status.
Slovenian: Injektor vam bo z zvočnimi in svetlobnimi signali posredoval svoje stanje.
English: 4817 ZK Breda The Netherlands
Slovenian: 4817 ZK Breda Nizozemska
English: Marketing Authorisation Holder and Manufacturer Amgen Europe B.V.
Slovenian: Imetnik dovoljenja za promet z zdravilom in izdelovalec Amgen Europe B.V.
English: Each pack contains 1 glass pre-filled syringe with an attached stainless steel needle and needle cap.
Slovenian: Vsaka škatla vsebuje 1 stekleno napolnjeno injekcijsko brizgo s pričvrščeno iglo iz nerjavečega jekla in pokrovčkom igle.
English: Hold the syringe barrel and gently take the cap from the needle without twisting.
Slovenian: Primite telo injekcijske brizge ter nežno in brez sukanja potegnite pokrovček z igle.
English: If the pre-filled syringe for manual administration is used with the on-body injector, the patient may receive less than the recommended dose.
Slovenian: Če je z injektorjem uporabljena napolnjena injekcijska brizga za ročno injiciranje, lahko bolnik dobi odmerek, manjši od priporočenega.
English: On-body injector placement Important: Contact your healthcare provider immediately if you have severe pain or skin discomfort around your on-body injector.
Slovenian: Namestitev injektorja Pomembno: Če imate hude bolečine ali nelagodje na koži okrog injektorja, se nemudoma posvetujte z zdravnikom.
English: Neulasta is injected subcutaneously via:
Slovenian: Zdravilo Neulasta se injicira subkutano z:
English: 9) was observed in younger children aged 0-5 years (8.9 days) compared to older children aged 6-11 years and 12-21 years (6 days and 3.7 days, respectively) and adults.
Slovenian: 9) (8,9 dni) kot pri starejših otrocih, starih od 6 do 11 let (6 dni) in 12 do 21 let (3,7 dni) in pri odraslih.
English: Do not attempt to activate the pre-filled syringe prior to injection.
Slovenian: Ne poskušajte aktivirati napolnjene injekcijske brizge pred injiciranjem.
English: Remember, any time you see a status light flashing red, call your healthcare provider immediately, as you may need a replacement dose.
Slovenian: Ne pozabite: vsakokrat, ko vidite, da lučka stanja rdeče utripa, se nemudoma posvetujte z zdravnikom, kajti morda boste potrebovali nadomestni odmerek.
English: Contact your healthcare provider immediately if you experience persistent or worsening redness or tenderness at the application site, as this can be a sign of infection.
Slovenian: Nemudoma se posvetujte z zdravnikom, če pordelost ali občutljivost na mestu namestitve traja ali se slabša, kajti to je lahko znak okužbe.
English: Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, 4.2).
Slovenian: Predpisovanje in izdaja zdravila je le s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: Syringe label Syringe barrel Syringe safety guard
Slovenian: Nalepka brizge Valj brizge Varnostni ščitnik brizge
English: Additionally a higher incidence of febrile neutropenia was observed in younger children aged 0-5 years (75%) compared to older children aged 6-11 years and 12-21 years (70% and 33%, respectively) and adults (see sections 4.8 and 5.2).
Slovenian: Poleg tega so pri mlajših otrocih, starih od 0 do 5 let, ugotovili večjo incidenco febrilne nevtropenije (75 %) kot pri starejših otrocih, starih od 6 do 11 (70 %) in 12 do 21 let (33 %) ter pri odraslih (glejte poglavji 4.8 in 5.2).
English: • if you get left upper abdominal pain or pain at the tip of your shoulder.
Slovenian: • če začutite bolečino levo zgoraj v trebuhu ali v predelu lopatice.
English: • if you have an allergy to latex.
Slovenian: • če ste alergični na lateks.
English: Solution for injection in a pack size of one single use pre-filled syringe (0.64 mL) and one on-body injector (Onpro kit).
Slovenian: Raztopina za injiciranje v pakiranju z eno napolnjeno injekcijsko brizgo (0,64 ml) za enkratno uporabo in enim injektorjem, ki se pritrdi na telo (komplet Onpro).
English: Pegfilgrastim has no or negligible influence on the ability to drive and use machines.
Slovenian: 4.7 Vpliv na sposobnost vožnje in upravljanja s stroji Pegfilgrastim nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja s stroji.
English: Your platelet count may become low which might result in bruising.
Slovenian: Število krvnih ploščic se vam lahko zmanjša, kar lahko povzroči nastajanje podplutb.
English: • a pre-filled syringe with on-body injector for automatic administration.
Slovenian: • napolnjeno injekcijsko brizgo in injektorjem, ki se pritrdi na telo, za avtomatično injiciranje.
English: Marketing Authorisation Holder Amgen Europe B.V.
Slovenian: Imetnik dovoljenja za promet z zdravilom Amgen Europe B.V.
English: • rash, itchy red raised bumps (contact dermatitis/local skin reactions) have been seen with the on-body injector.
Slovenian: • med uporabo injektorja so opažali izpuščaj, srbeče, rdeče dvignjene bulice (kontaktni dermatitis/lokalne kožne reakcije).
English: The grey needle cap of the pre-filled syringe contains dry natural rubber, which is derived from latex.
Slovenian: Sivi pokrovček igle na napolnjeni injekcijski brizgi vsebuje suho naravno gumo, pridobljeno iz lateksa.
English: Do not grasp the grey needle cap.
Slovenian: Ne primite brizge za sivi pokrovček igle.
English: • if you experience a cough, fever and difficulty breathing.
Slovenian: • če začnete kašljati, se vam zviša telesna temperatura in začnete težko dihati.
English: • Be careful not to bump or knock the on-body injector off your body.
Slovenian: • Pazite, da injektorja ne zadenete in ne zbijete s telesa.
English:  Status light is solid green or the status light has switched off.
Slovenian:  Lučka stanja je stalno zelena ali se je izključila.
English: For a more comfortable injection, let the pre-filled syringe stand for 30 minutes to reach room temperature or hold the pre-filled syringe gently in your hand for a few minutes.
Slovenian: Da bo injiciranje manj neprijetno, pustite napolnjeno injekcijsko brizgo stati 30 minut zunaj hladilnika, da bo dosegla sobno temperaturo, ali jo nekaj minut previdno držite v roki.
English: Studies in rats indicated that reproductive performance, fertility, oestrous cycling, days between pairing and coitus, and intrauterine survival were unaffected by pegfilgrastim given subcutaneously.
Slovenian: Študije na podganah so pokazale, da subkutano dajanje pegfilgrastima ne vpliva na sposobnost razmnoževanja, plodnost, obdobje estrusa, dneve med parjenjem in koitusom ter intrauterino preživetje.
English: In a phase II (n = 37) multicentre, randomised, open-label study of paediatric sarcoma patients receiving 100 mcg/kg pegfilgrastim following cycle 1 of vincristine, doxorubicin and cyclophosphamide (VAdriaC/IE) chemotherapy, a longer duration of severe neutropenia (neutrophils < 0.5 x 10
Slovenian: faze pri pediatričnih bolnikih s sarkomom (n = 37), ki so dobili 100 µg/kg pegfilgrastima po 1. ciklusu kemoterapije z vinkristinom, doksorubicinom in ciklofosfamidom (VAdriaC/IE), so pri mlajših otrocih, starih od 0 do 5 let, ugotovili dolgotrajnejšo hudo nevtropenijo (nevtrofilci < 0,5 x 10
English: • if you experience an allergic reaction including weakness, drop in blood pressure, difficulty breathing, swelling of the face (anaphylaxis), redness and flushing, skin rash and areas of the skin that itch.
Slovenian: • če se vam pojavi alergijska reakcija, vključno s šibkostjo, padcem krvnega tlaka, težavami z dihanjem, otekanjem obraza (anafilaksa), pordelostjo in navali vročine, izpuščajem na koži in predeli kože, ki srbijo.
English: What Neulasta contains
Slovenian: Kaj vsebuje zdravilo Neulasta
English: Noticeably wet (saturated) adhesive Dripping fluid from on-body injector
Slovenian: Opazno vlažno (napojeno) lepilo Kapljanje tekočine z injektorja
English: Remove and save the pre-filled syringe label.
Slovenian: Odstranite in shranite nalepko z napolnjene injekcijske brizge.
English: On-body injector for Neulasta 6 mg solution for injection Patient instructions for use
Slovenian: Injektor, ki se pritrdi na telo (injektor), za zdravilo Neulasta 6 mg raztopina za injiciranje Navodila za uporabo za bolnika
English: When administering using the manual pre-filled syringe, allow the pre-filled syringe to reach room temperature before injecting.
Slovenian: V primeru uporabe napolnjene injekcijske brizge za ročno injiciranje pustite napolnjeno injekcijsko brizgo, da pred injiciranjem doseže sobno temperaturo.
English: Pinch (without squeezing) the skin using your thumb and forefinger.
Slovenian: Kožo primite (ne da bi jo stiskali) med palec in kazalec.
English: The needle cap of the pre-filled syringe contains dry natural rubber (a derivative of latex), which may cause allergic reactions.
Slovenian: Pokrovček igle pri napolnjeni injekcijski brizgi vsebuje suho naravno gumo (derivat lateksa), ki lahko povzroča alergične reakcije.
English: Serious allergic reactions, including anaphylaxis can occur in patients receiving pegfilgrastim (uncommon) (see section 4.4).
Slovenian: Bolnikom, ki prejemajo pegfilgrastim, se lahko pojavijo resne alergijske reakcije, vključno z anafilaksijo (občasno) (glejte poglavje 4.4).
English: The pre-filled syringe for use with the on-body injector may be exposed at room temperature for no longer than 36 hours prior to filling the on-body injector.
Slovenian: Napolnjena injekcijska brizga, namenjena za uporabo z injektorjem, sme biti na sobni temperaturi največ 36 ur pred polnjenjem injektorja.
English: Do not grasp the plunger.
Slovenian: Ne primite brizge za bat.
English: There is insufficient information on the excretion of pegfilgrastim/metabolites in human milk, a risk to the newborns/infants cannot be excluded.
Slovenian: Ni dovolj podatkov o izločanju pegfilgrastima/presnovkov v materino mleko.
English: • are planning to have a baby.
Slovenian: • načrtujete zanositev.
English: Aortitis has been reported after G-CSF administration in healthy subjects and in cancer patients.
Slovenian: Po dajanju G-CSF zdravim osebam in bolnikom z rakom so poročali o aortitisu.
English: Do not try to inject yourself if you have not been trained.
Slovenian: Če vas samoinjiciranja še niso naučili, si ne poskušajte sami dajati injekcij.
English: If it is flashing red, contact your healthcare provider immediately.
Slovenian: Če utripa rdeče, se nemudoma posvetujte z zdravnikom.
English: Pack size of one pre-filled syringe in blistered packaging co-packed with an on-body injector.
Slovenian: Velikost pakiranja z eno napolnjeno injekcijsko brizgo v pretisnem pakiranju, pakirano skupaj z injektorjem.
English: Neulasta contains the active substance pegfilgrastim.
Slovenian: Zdravilo Neulasta vsebuje učinkovino pegfilgrastim.
English: No dose change is recommended in patients with renal impairment, including those with end-stage renal disease.
Slovenian: Pri bolnikih z okvaro ledvic odmerka ni treba spreminjati; to velja tudi za bolnike s končno odpovedjo ledvic.
English: Fill indicator
Slovenian: Kazalnik polnosti
English: Leukocytosis
Slovenian: Levkocitoza
English: Pre-filled syringe (Type I glass), with a rubber stopper, stainless steel needle and needle cap with or without an automatic needle guard.
Slovenian: Napolnjena injekcijska brizga (iz stekla tipa I) z gumijastim zamaškom, nerjavečo jekleno iglo in pokrovčkom igle z avtomatskim ščitnikom igle ali brez njega.
English: Do not attempt to remove the clear pre-filled syringe safety guard from the pre-filled syringe.
Slovenian: Ne poskušajte odstraniti prozornega varnostnega ščitnika z napolnjene injekcijske brizge.
English: Neulasta contains sorbitol (E420) and sodium acetate
Slovenian: Zdravilo Neulasta vsebuje sorbitol (E420) in natrijev acetat
English: Pegfilgrastim Conc.
Slovenian: pegfilgrastima ANC
English: Do not remove the grey needle cap from the pre-filled syringe until you are ready to inject.
Slovenian: Ne odstranite sivega pokrovčka igle z napolnjene injekcijske brizge, dokler niste pripravljeni za injiciranje.
English: MedDRA system organ class
Slovenian: Organski sistem po MedDRA
English: If the on-body injector was placed on the back of your arm, a caregiver must be available to monitor its status.
Slovenian: Če je bil telesni injektor nameščen na zadnjo stran nadlakta, morate imeti na voljo skrbnika, ki nadzoruje stanje injektorja.
English: Excipients: sodium acetate, sorbitol (E420), polysorbate 20, water for injections.
Slovenian: Pomožne snovi: natrijev acetat, sorbitol (E420), polisorbat 20, voda za injekcije.
English: Finger grips
Slovenian: Oprijemalo za prste
English: • coughing up blood (haemoptysis).
Slovenian: • izkašljevanje krvi (hemoptiza).
English: In two randomised, double-blind, pivotal studies in patients with high-risk stage II-IV breast cancer undergoing myelosuppressive chemotherapy consisting of doxorubicin and docetaxel, use of pegfilgrastim, as a single once per cycle dose, reduced the duration of neutropenia and the incidence of febrile neutropenia similarly to that observed with daily administrations of filgrastim (a median of 11 daily administrations).
Slovenian: do IV. stadiju na mielosupresivni kemoterapiji z doksorubicinom in docetakselom je uporaba pegfilgrastima v obliki enega samega odmerka na cikel skrajšala trajanje nevtropenije in incidenco febrilne nevtropenije, podobno kot so opazili pri vsakodnevni uporabi filgrastima (mediana števila dnevnih aplikacij je bila 11).