FrancophonIA/ELRC3.0 huggingface dataset:
English: Signifor 0.3 mg solution for injection Signifor 0.6 mg solution for injection Signifor 0.9 mg solution for injection
Danish: Signifor 0,3 mg injektionsvæske, opløsning Signifor 0,6 mg injektionsvæske, opløsning Signifor 0,9 mg injektionsvæske, opløsning
English: For further details on handling, see section 6.6.
Danish: Yderligere detaljer vedrørende håndtering er angivet i pkt.
English: Signifor 20 mg: each vial contains 20 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 20 mg: Et hætteglas indeholder 20 mg pasireotid (som pasireotidpamoat).
English: Pull the protective cover straight off the needle.
Danish: Træk beskyttelseshætten af kanylen med en lige bevægelse.
English: What Signifor looks like and contents of the pack Signifor solution for injection is a clear, colourless solution in an ampoule.
Danish: Signifor injektionsvæske er en klar, farveløs opløsning i en ampul.
English: Signifor 0.6 mg solution for injection EU/1/12/753/005-008
Danish: Signifor 0,6 mg injektionsvæske, opløsning EU/1/12/753/005-008
English: pimozide, haloperidol, tiapride, amisulpride, sertindole, methadone); - medicines to treat hay fever and other allergies (terfenadine, astemizole, mizolastine); - medicines used in the prevention or treatment of malaria (chloroquine, halofantrine,
Danish: fluphenazin, pimozid, haloperidol, tiaprid, amisulprid, sertindol, metadon); - medicin, der bruges til at behandle høfeber og andre allergier (terfenadin, astemizol,
English: Patients should receive instructions from the physician or a healthcare professional on how to inject Signifor subcutaneously.
Danish: Patienterne skal vejledes i subkutan injektion af Signifor af en læge eller sygeplejerske.
English: Monitoring of liver enzymes is recommended before and during treatment with Signifor (see section 4.4), as clinically appropriate.
Danish: Det anbefales at monitorere leverenzymtallet før og under behandling med Signifor (se pkt.
English: Signifor 0.3 mg solution for injection Signifor 0.6 mg solution for injection Signifor 0.9 mg solution for injection pasireotide
Danish: Signifor 0,3 mg injektionsvæske, opløsning Signifor 0,6 mg injektionsvæske, opløsning Signifor 0,9 mg injektionsvæske, opløsning pasireotid
English: Signifor 0.9 mg solution for injection EU/1/12/753/009-0012
Danish: Signifor 0,9 mg injektionsvæske, opløsning EU/1/12/753/009-012
English: What Signifor is and what it is used for What you need to know before you use Signifor How to use Signifor
Danish: Det skal du vide, før du begynder at bruge Signifor Sådan skal du bruge Signifor Bivirkninger
English: Doses up to 2.1 mg twice a day have been used in healthy volunteers, with the adverse reaction diarrhoea being observed at a high frequency.
Danish: Hos raske forsøgspersoner er bivirkningen diaré observeret med høj frekvens ved doseringer på op til 2,1 mg to gange dagligt.
English: Signifor 0.3 mg solution for injection EU/1/12/753/001-004
Danish: Signifor 0,3 mg injektionsvæske, opløsning EU/1/12/753/001-004
English: Vomiting, abdominal pain upper
Danish: Opkastning, øvre abdominalsmerter
English: Compound hsst1
Danish: Forbindelse hsst1
English: Signifor 60 mg powder and solvent for suspension for injection EU/1/12/753/016-017
Danish: Signifor 60 mg pulver og solvens til injektionsvæske, suspension EU/1/12/753/016-017
English: Signifor 60 mg: each vial contains 60 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 60 mg: Et hætteglas indeholder 60 mg pasireotid (som pasireotidpamoat).
English: If you are not sure about giving yourself the injection or if you have any questions, please ask your doctor or nurse for help.
Danish: Spørg lægen eller sygeplejersken til råds, hvis du ikke føler dig sikker i at give dig selv en injektion, eller hvis du har spørgsmål.
English: Signifor 20 mg powder and solvent for suspension for injection One vial contains 20 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 20 mg pulver og solvens til injektionsvæske, suspension Et hætteglas indeholder 20 mg pasireotid (som pasireotidpamoat).
English: 1 pre-filled syringe with 2 ml solvent 1 safety-engineered needle 1 vial adapter
Danish: 1 hætteglas med pulver 1 fyldt injektionssprøjte med 2 ml solvens 1 sikkerhedskanyle
English: Signifor is to be administered subcutaneously by self injection.
Danish: Signifor skal indgives subkutant ved selvinjektion.
English: Always keeping your skin pinched, slowly press the plunger down as far as it will go until all the solution is injected.
Danish: Bliv ved med at knibe huden sammen ved injektionsstedet og pres langsomt stemplet helt i bund, indtil hele injektionssprøjtens indhold er sprøjtet ind. Hold stemplet nede, og lad injektionssprøjten sidde i 5 sekunder.
English: Signifor 30 mg: each vial contains 30 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 30 mg: Et hætteglas indeholder 30 mg pasireotid (som pasireotidpamoat).
English: Signifor 20 mg is available in unit packs containing one vial of powder with 20 mg pasireotide and one pre-filled syringe with 2 ml solvent.
Danish: Signifor 20 mg fås i enkeltpakninger, der indeholder et hætteglas med pulver med 20 mg pasireotid og en fyldt injektionssprøjte med 2 ml solvens.
English: Liver tests
Danish: Levertests
English: Signifor 40 mg: each vial contains 40 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 40 mg: Et hætteglas indeholder 40 mg pasireotid (som pasireotidpamoat).
English: One vial contains 20 mg pasireotide (as pasireotide pamoate).
Danish: 1 hætteglas indeholder 20 mg pasireotid (som pasireotidpamoat).
English: - If you have any further questions, ask your doctor, nurse or pharmacist.
Danish: Er du i tvivl, så spørg lægen eller apotekspersonalet.
English: Signifor 10 mg: each vial contains 10 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 10 mg: Et hætteglas indeholder 10 mg pasireotid (som pasireotidpamoat).
English: 1 ml solution for injection contains 0.9 mg pasireotide (as pasireotide diaspartate).
Danish: 1 ml injektionsvæske, opløsning indeholder 0,9 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 40 mg powder and solvent for suspension for injection EU/1/12/753/014-015
Danish: Signifor 40 mg pulver og solvens til injektionsvæske, suspension EU/1/12/753/014-015
English: One vial contains 60 mg pasireotide (as pasireotide pamoate).
Danish: 1 hætteglas indeholder 60 mg pasireotid (som pasireotidpamoat).
English: Signifor 20 mg powder for injection pasireotide
Danish: Signifor 20 mg pulver til injektion pasireotid i.m.
English: 1 ml solution for injection contains 0.6 mg pasireotide (as pasireotide diaspartate).
Danish: 1 ml injektionsvæske, opløsning indeholder 0,6 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 60 mg powder and solvent for suspension for injection One vial contains 60 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 60 mg pulver og solvens til injektionsvæske, suspension Et hætteglas indeholder 60 mg pasireotid (som pasireotidpamoat).
English: Signifor 0.9 mg: One ampoule of 1 ml solution contains 0.9 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,9 mg: En ampul med 1 ml opløsning indeholder 0,9 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 30 mg powder and solvent for suspension for injection One vial contains 30 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 30 mg pulver og solvens til injektionsvæske, suspension Et hætteglas indeholder 30 mg pasireotid (som pasireotidpamoat).
English: Signifor 30 mg is available in unit packs containing one vial of powder with 30 mg pasireotide and one pre filled syringe with 2 ml solvent.
Danish: Signifor 30 mg fås i enkeltpakninger, der indeholder et hætteglas med pulver med 30 mg pasireotid og en fyldt injektionssprøjte med 2 ml solvens.
English: Signifor 10 mg powder and solvent for suspension for injection EU/1/12/753/018
Danish: Signifor 10 mg pulver og solvens til injektionsvæske, suspension EU/1/12/753/018
English: Signifor 60 mg is available in unit packs containing one vial of powder with 60 mg pasireotide and one pre-filled syringe with 2 ml solvent.
Danish: Signifor 60 mg fås i enkeltpakninger, der indeholder et hætteglas med pulver med 60 mg pasireotid og en fyldt injektionssprøjte med 2 ml solvens.
English: One vial contains 40 mg pasireotide (as pasireotide pamoate).
Danish: 1 hætteglas indeholder 40 mg pasireotid (som pasireotidpamoat).
English: Signifor 10 mg powder for injection pasireotide
Danish: Signifor 10 mg pulver til injektion pasireotid i.m.
English: One vial contains 10 mg pasireotide (as pasireotide pamoate).
Danish: 1 hætteglas indeholder 10 mg pasireotid (som pasireotidpamoat).
English: If you use more Signifor than you should
Danish: Hvis du har taget for meget Signifor
English: Signifor 40 mg is available in unit packs containing one vial of powder with 40 mg pasireotide and one pre-filled syringe with 2 ml solvent.
Danish: Signifor 40 mg fås i enkeltpakninger, der indeholder et hætteglas med pulver med 40 mg pasireotid og en fyldt injektionssprøjte med 2 ml solvens.
English: Signifor 30 mg powder for injection pasireotide
Danish: Signifor 30 mg pulver til injektion pasireotid i.m.
English: Signifor 40 mg powder and solvent for suspension for injection One vial contains 40 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 40 mg pulver og solvens til injektionsvæske, suspension Et hætteglas indeholder 40 mg pasireotid (som pasireotidpamoat).
English: Signifor 40 mg powder for injection pasireotide
Danish: Signifor 40 mg pulver til injektion pasireotid i.m.
English: Injection sites angle
Danish: Injektionssteder
English: Signifor 0.9 mg injection pasireotide
Danish: Signifor 0,9 mg injektionsvæske pasireotid s.c.
English: Signifor 10 mg is available in unit packs containing one vial of powder with 10 mg pasireotide and one pre filled syringe with 2 ml solvent.
Danish: Signifor 10 mg fås i enkeltpakninger, der indeholder et hætteglas med pulver med 10 mg pasireotid og en fyldt injektionssprøjte med 2 ml solvens.
English: Signifor 10 mg powder and solvent for suspension for injection One vial contains 10 mg pasireotide (as pasireotide pamoate).
Danish: Signifor 10 mg pulver og solvens til injektionsvæske, suspension Et hætteglas indeholder 10 mg pasireotid (som pasireotidpamoat).
English: Signifor 0.9 mg solution for injection One ampoule of 1 ml contains 0.9 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,9 mg injektionsvæske, opløsning En ampul med 1 ml indeholder 0,9 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 60 mg powder for injection pasireotide
Danish: Signifor 60 mg pulver til injektion pasireotid i.m.
English: Signifor 0.6 mg injection pasireotide
Danish: Signifor 0,6 mg injektionsvæske pasireotid s.c.
English: One vial contains 30 mg pasireotide (as pasireotide pamoate).
Danish: 1 hætteglas indeholder 30 mg pasireotid (som pasireotidpamoat).
English: Signifor 0.6 mg: One ampoule of 1 ml solution contains 0.6 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,6 mg: En ampul med 1 ml opløsning indeholder 0,6 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 20 mg powder and solvent for suspension for injection EU/1/12/753/013
Danish: Signifor 20 mg pulver og solvens til injektionsvæske, suspension EU/1/12/753/013
English: 1 ml solution for injection contains 0.3 mg pasireotide (as pasireotide diaspartate).
Danish: 1 ml injektionsvæske, opløsning indeholder 0,3 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 0.6 mg solution for injection One ampoule of 1 ml contains 0.6 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,6 mg injektionsvæske, opløsning En ampul med 1 ml indeholder 0,6 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 0.3 mg: One ampoule of 1 ml solution contains 0.3 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,3 mg: En ampul med 1 ml opløsning indeholder 0,3 mg pasireotid (som pasireotiddiaspartat).
English: Signifor 30 mg powder and solvent for suspension for injection EU/1/12/753/019
Danish: Signifor 30 mg pulver og solvens til injektionsvæske, suspension EU/1/12/753/019
English: Signifor 0.3 mg solution for injection One ampoule of 1 ml contains 0.3 mg pasireotide (as pasireotide diaspartate).
Danish: Signifor 0,3 mg injektionsvæske, opløsning En ampul med 1 ml indeholder 0,3 mg pasireotid (som pasireotiddiaspartat).
English: INSTRUCTIONS FOR USE OF SIGNIFOR SOLUTION FOR INJECTION
Danish: BRUGSANVISNING TIL SIGNIFOR INJEKTIONSVÆSKE, OPLØSNING
English: Signifor 20 mg powder and solvent for suspension for injection pasireotide
Danish: Signifor 20 mg pulver og solvens til injektionsvæske, suspension pasireotid
English: Signifor 0.3 mg injection pasireotide
Danish: Signifor 0,3 mg injektionsvæske pasireotid s.c.
English: Signifor 60 mg powder and solvent for suspension for injection pasireotide
Danish: Signifor 60 mg pulver og solvens til injektionsvæske, suspension pasireotid
English: Signifor 10 mg powder and solvent for suspension for injection pasireotide
Danish: Signifor 10 mg pulver og solvens til injektionsvæske, suspension pasireotid
English: Signifor 40 mg powder and solvent for suspension for injection pasireotide
Danish: Signifor 40 mg pulver og solvens til injektionsvæske, suspension pasireotid
English: Signifor 30 mg powder and solvent for suspension for injection pasireotide
Danish: Signifor 30 mg pulver og solvens til injektionsvæske, suspension pasireotid
English: The dose could be reduced by decrements of 0.3 mg twice daily at any time during the study for reasons of intolerability.
Danish: Hvis dosis ikke kunne tåles, kunne den til enhver tid reduceres i trin på 0,3 mg to gange dagligt.
English: 1 vial of powder
Danish: 1 hætteglasadapter
English: Remove the cover from the needle.
Danish: Fjern kanylens beskyttelseshylster.
English: Coagulation abnormalities
Danish: Binyrebarkinsufficiens
English: Unscrew the syringe from the vial adapter.
Danish: Skru sprøjten af hætteglasadapteren.
English: Pasireotide has been shown to prolong the QT interval on the ECG in two dedicated healthy volunteer studies.
Danish: at pasireotid forlænger QT-intervallet i EKG.
English: Cholelithiasis
Danish: Dosering
English: procainamide, quinidine, sotalol, dofetilide, ibutilide, amiodarone or dronedarone; - medicines to treat bacterial infections (by mouth: clarithromycin, moxifloxacin; via injection:
Danish: Du skal specielt fortælle din læge, hvis du bruger: - medicin, der bruges til at behandle uregelmæssig hjerterytme, som fx medicin der indeholder disopyramid, procainamid, quinidin, sotalol, dofetilid, ibutilid, amiodaron eller dronedaron; - medicin, der bruges til at behandle bakterieinfektioner (indtagelse igennem munden:
English: Alcohol wipes or similar
Danish: Spritservietter
English: 4 vials + 8 swabs
Danish: 4 hætteglas + 8 alkoholservietter
English: 25 mg Powder for solution for injection
Danish: 25 mg Pulver til injektionsvæske, opløsning powder: vial (glass)
English: 24 vials + 24 prefilled syringes + 24 needles + 24 vial adaptors + 48 swabs
Danish: 0,5 ml (50 mg/ml) 12 fyldte injektionssprøøjter + 12 alkoholservietter
English: Section 4.8.
Danish: Punkt 4.8.
English: Adopted at the 11-14 April 2016 PRAC
Danish: Vedtaget på PRAC's møde 11.-14. april 2016
English: Olanzapine - Drug reaction with eosinophilia and systemic symptoms (DRESS)(EPITT no 18534)
Danish: Olanzapin - Lægemiddelfremkaldt reaktion med eosinofili og systemiske symptomer (DRESS)(EPITT nr. 18534)
English: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) (frequency unknown)
Danish: Lægemiddelfremkaldt reaktion med eosinofili og systemiske symptomer (DRESS) (hyppighed ikke kendt)
English: They shall be removed or replaced by accurate medical terms.
Danish: De skal enten slettes eller erstattes af nøjagtige medicinske termer.
English: The PRAC adopted a recommendation on 16 October 2018 which was then considered by the CHMP, in accordance with Article 107k of Directive 2001/83/EC.
Danish: PRAC har den 16. oktober 2018 vedtaget en anbefaling, der efterfølgende er blevet vurderet af CHMP, jf. artikel 107k i direktiv 2001/83/EF.
English: Therefore, PRAC concluded that these indications should be maintained.
Danish: PRAC fandt derfor, at disse indikationer bør fastholdes.
English: The PRAC also reviewed all data submitted by different stakeholders, both before and after, the public hearing.
Danish: PRAC gennemgik også alle data, som forskellige interessenter havde indsendt såvel før som efter den offentlige høring.
English: Most cases of travellers' diarrhoea are self-limiting and resolve spontaneously within 3-5 days.
Danish: De fleste tilfælde af turistdiarré er selvbegrænsende og forsvinder spontant inden for 3-5 dage.
English: (2) or the terminology is incorrect from a medical perspective.
Danish: (2) eller terminologien ikke er korrekt set fra et medicinsk synspunkt.
English: Other indications were found to be incorrectly formulated in medical terms.
Danish: Andre indikationer blev fundet at være formuleret med forkerte medicinske termer.
English: Based on the review of available scientific data, cases of uncomplicated cystitis have been often described as self-limiting.
Danish: Baseret på gennemgangen af tilgængelige videnskabelige data er tilfælde af ukompliceret cystitis ofte blevet beskrevet som selvbegrænsende.
English: Therefore these broad indications need to be amended.
Danish: Derfor er det nødvendigt at ændre disse brede indikationer.
English: Indications in this category are amended (please refer to Annex III) as they are either:
Danish: Indikationerne i denne kategori ændres (se bilag III), da:
English: This included the responses submitted by the marketing authorisation holders in writing as well as the outcomes of consultations with the Infectious Disease Working Party.
Danish: Det omfattede blandt andet de skriftlige svar, som indehaverne af markedsføringstilladelse havde indsendt, samt udfaldet af høringerne af arbejdsgruppen vedrørende smitsomme sygdomme.
English: In addition, the PRAC considered the views of patient organisations, patients, families and carers, and the views of healthcare professionals in a public hearing.
Danish: Derudover vurderede PRAC de synspunkter, som patientorganisationer, patienter, pårørende og omsorgspersoner samt sundhedspersoner havde givet udtryk for i en offentlig høring.
English: Details of the amendments/ rewording of category 4 indications mentioned in tables 4 and 5 above are provided in Annex III of the CHMP opinion.
Danish: Oplysninger om ændringerne/omformuleringerne af kategori 4-indikationerne i tabel 4 og 5 ovenfor er anført i bilag III til CHMP's udtalelse.
English: Generally, the most bronchial infections are of viral origin.
Danish: Generelt er de fleste bronkiale infektioner af viral oprindelse.
English: Thus, the indication septicaemia should be deleted.
Danish: Indikationen sepsis bør derfor slettes.
English: In these infections complicated course as well as high level of the resistant pathogens should be expected.
Danish: Ved disse infektioner bør et kompliceret forløb samt et højt niveau af resistente patogener forventes.
English: Boader-spectrum antibiotics should not be used for peri-procedural prophylaxis or only cautiously in very selective cases (The 2015 European Association of Urology (EAU) guidelines on Urological infections).
Danish: Bredspektret antibiotika bør ikke anvendes til perioperativ profylakse eller kun med forsigtighed i meget selektive tilfælde (The 2015 European Association of Urology (EAU) guidelines on Urological infections).
English: • Category 4: The Indications are considered too broad in view of the evidence available and related to some (sub) indications mentioned in categories 1, 2 or 3 above.
Danish: • Kategori 4: Indikationerne anses for at være for brede i lyset af den tilgængelige evidens og relateret til nogle af de (under)indikationer, der er nævnt i kategori 1, 2 eller 3 ovenfor.
English: Category 4: rewording of indications according to the current medical knowledge
Danish: Kategori 4: omformulering af indikationer i henhold til gældende medicinsk viden
English: Antimicrobial prophylaxis can be given only after counselling and behavioural modification has been attempted and when nonantimicrobial measures have been unsuccessful.
Danish: Antimikrobiel profylakse kan kun gives efter, at rådgivning og adfærdsændring er forsøgt, og når ikkeantimikrobielle foranstaltninger ikke har haft effekt.
English: (Fluoro)quinolones have been approved in the EU for a diversity of indications - over one hundred indications of various granularities.
Danish: (Fluor)quinoloner er godkendt i EU i mange forskellige indikationer (over 100 indikationer af forskellig karakter).
English: Therefore, septicaemia is not acceptable as a stand-alone indication as per the Note for Guidance (CPMP/EWP/558/95 rev 2).
Danish: Derfor er sepsis ikke acceptabelt som en selvstændig indikation i henhold til Note for Guidance (CPMP/EWP/558/95 rev 2).
English: After review of the available data, mainly based on animal models (Giamarellou H et al. 1989), efficacy of pefloxacin cannot be established.
Danish: Efter gennemgang af de tilgængelige data, der primært er baseret på dyremodeller (Giamarellou H. et al., 1989), kan virkningen af pefloxacin ikke fastslås.
English: These indications shall be amended.
Danish: Disse indikationer skal ændres.
English: About 80% cases of rhinosinusitis occurring in clinical practice are of viral origin and only a negligible proportion of these cases (i.e. 0,5-2%) develop to bacterial infection (Gwaltney 1996).
Danish: Ca. 80 % af tilfældene af rhinosinuit, der ses i klinisk praksis, er af viral oprindelse, og kun en ubetydelig andel af disse tilfælde (dvs. 0,5-2 %) udvikler sig til en bakterieinfektion (Gwaltney 1996).
English: Reviewed European guidelines do not discuss an option of non-antibacterial therapy of urinary tract infections.
Danish: De gennemgåede europæiske retningslinjer indeholder ikke en diskussion af muligheden for ikkeantibakteriel behandling af urinvejsinfektioner.
English: Table 4 - Category 4 indications that are considered too broad
Danish: Tabel 4 - kategori 4-indikationer, der anses for at være for brede
English: • The PRAC concluded that in case of milder infections, other treatment options should be considered.
Danish: • PRAC vurderede, at andre behandlingsmuligheder bør overvejes i tilfælde af mildere infektioner.
English: According to the current evidence and in line with the European guidelines (Woodhead et al. 2005, 2011), there is a modest benefit in using antibiotics for acute bronchitis in otherwise healthy individuals.
Danish: I henhold til den aktuelle evidens og i overensstemmelse med de europæiske retningslinjer (Woodhead et al., 2005, 2011) er der en beskeden fordel ved brug af antibiotika mod akut bronkitis hos ellers raske personer.
English: In cases with Candida present on microscopy or culture, antifungals must be tried first, in order to see if other treatment is still needed.
Danish: I tilfælde, hvor Candida er til stede efter mikroskopi eller dyrkning, skal antimykotika forsøges først for at se, om anden behandling stadig er nødvendigt.
English: The recent study by Gágyor et al (2015) showed that two thirds of women with uncomplicated urinary tract infection treated with ibuprofen recovered without any antibiotics.
Danish: Det nylige studie af Gágyor et al. (2015) viste, at to tredjedele af kvinder med ukompliceret urinvejsinfektion, der blev behandlet med ibuprofen, kom sig uden antibiotika.
English: Urethritis and cervicitis
Danish: Uretritis og cervicitis
English: These substances inhibit synthesis of bacterial DNA via binding to intracellular topoisomerase enzymes and forming drug-enzyme-DNA complexes.
Danish: Disse stoffer hæmmer syntesen af bakterielt dna via binding til intracellulære topoisomerase-enzymer og dannelse af lægemiddel-enzym-dna-komplekser.
English: There is no avalaible data establishing efficacy in this clinical setting.
Danish: Der foreligger ingen data, der fastslår effekten i klinisk praksis.