FrancophonIA/ELRC3.0 huggingface dataset:
English: The plasma half-life in adults was 7±1 hours and did not vary either with dose, route of administration or repeated administration.
Slovenian: Plazemski razpolovni čas pri odraslih je 7  1 ur in se ne spreminja z odmerkom, potjo uporabe ali ponavljajočo se uporabo.
English: • swelling of the face, lips, tongue and throat (Quincke's oedema)
Slovenian: • otekanje obraza, ustnic, jezika in žrela (Quinckejev edem)
English: If you notice any slow down in the growth or unexpected puberty development of your child, please contact your doctor.
Slovenian: če ste pri otroku opazili počasnejšo rast ali nepričakovan razvoj v puberteti, se posvetujte z zdravnikom.
English: The physician should prescribe the most appropriate pharmaceutical form, presentation and strength according to age, weight and dose.
Slovenian: Zdravnik mora glede na starost, telesno maso in odmerek predpisati najustreznejšo farmacevtsko obliko, velikost pakiranja in jakost.
English: • decreased number of blood platelets, decreased number of white blood cells;
Slovenian: zmanjšano število krvnih ploščic, zmanjšano število belih krvnih celic;
English: The dialyser extraction efficiency is 60% for levetiracetam and 74% for the primary metabolite.
Slovenian: Učinkovitost dializne ekstrakcije levetiracetama je 60 %, primarnega presnovka pa 74 %.
English: CLcr (ml/min/1.73 m 2) = ---------------------------- x 1.73 BSA subject (m
Slovenian: CLcr (ml/min/1,73 m 2) = ----------------------- x 1,73 BSA bolnika (m
English: Following dialysis, a 250 to 500 mg supplemental dose is recommended.
Slovenian: Po dializi je priporočljiv dodatni odmerek od 250 do 500 mg.
English: Withdrawal Volume Volume of Diluent
Slovenian: Odmerek Odvzeti volumen Volumen redčila
English: Results related to behavioural and emotional functioning indicated a worsening in levetiracetam treated patients on aggressive behaviour as measured in a standardised and systematic way using a validated instrument (CBCL - Achenbach Child Behaviour Checklist).
Slovenian: Rezultati povezani z vedenjskimi in emocionalnimi funkcijami kažejo pri bolnikih, ki se zdravijo z levetiracetamom, poslabšanje agresivnega obnašanja, ki se izmeri na standardiziran in sistematičen način z uporabo validiranega merskega instrumenta (CBCL - Achenbach Child Behavior Checklist).
English: Levetiracetam Hospira may impair your ability to drive or operate any tools or machinery, as it may make you feel sleepy.
Slovenian: Zdravilo Levetiracetam Hospira lahko oslabi vašo sposobnost vožnje ali upravljanja z orodjem ali stroji, saj lahko zdravilo Levetiracetam Hospira povzroči zaspanost.
English: In addition, it partially reverses the reductions in GABA- and glycine-gated currents induced by zinc and β-carbolines.
Slovenian: Poleg tega delno preprečuje inhibicijo GABA in glicinskih kanalov povzročeno z Zn in β- karbolini.
English: Furthermore, levetiracetam has been shown in in vitro studies to bind to a specific site in rodent brain tissue.
Slovenian: Nadalje se je za levetiracetam v in vitro študijah pokazalo, da se veže na specifično mesto v možganskem tkivu glodalcev.
English: Adverse reactions reported in clinical studies (adults, adolescents, children and infants > 1 month) and from post-marketing experience are listed in the following table per System Organ Class and per frequency.
Slovenian: Neželeni učinki, o katerih so poročali v kliničnih študijah (odrasli, mladostniki, otroci in dojenčki, starejši od 1 meseca) in v postmarketinškem obdobju, so navedeni v spodnji preglednici po organskih sistemih in pogostnosti.
English: Due to possible different individual sensitivity, some patients might experience somnolence or other central nervous system related symptoms, especially at the beginning of treatment or following a dose increase.
Slovenian: Pri nekaterih bolnikih se lahko zaradi različne individualne občutljivosti predvsem na začetku zdravljenja ali po povečanju odmerka pojavi somnolenca ali drugi simptomi, povezani s centralnim živčnim sistemom.
English: Box of 10 or 25 vials
Slovenian: Škatla z 10 ali 25 vialami
English: Pre-marketing data from clinical studies conducted in adults indicate that levetiracetam did not influence the serum concentrations of existing antiepileptic medicinal products (phenytoin, carbamazepine, valproic acid, phenobarbital, lamotrigine, gabapentin and primidone) and that these antiepileptic medicinal products did not influence the pharmacokinetics of levetiracetam.
Slovenian: Predmarketinški podatki iz kliničnih študij, izvedenih pri odraslih kažejo, da levetiracetam ne vpliva na serumsko koncentracijo drugih antiepileptičnih zdravil (fenitoina, karbamazepina, valprojske kisline, fenobarbitala, lamotrigina, gabapentina in primidona), in da ta antiepileptična zdravila ne vplivajo na farmakokinetiko levetiracetama.
English: Six-month seizure freedom was achieved in 73.0% of levetiracetam-treated patients and 72.8% of carbamazepine-CR treated patients; the adjusted absolute difference between treatments was 0.2% (95% CI:-7.8 8.2).
Slovenian: 73,0 % bolnikov, ki so se zdravili z levetiracetamom, in 72,8 % bolnikov, ki so se zdravili s karbamazepinom z nadzorovanim sproščanjem (CR) je bilo šest mesecev brez napadov; prilagojena absolutna razlika med zdravljenjema je bila 0,2 % (95-% CI: 7,8-8,2).
English: Пфайзер Люксембург САРЛ, Клон България Тел.
Slovenian: Пфайзер Люксембург САРЛ, Клон БългарияHospira UK Limited Тел.
English: This binding site is the synaptic vesicle protein 2A, believed to be involved in vesicle fusion and neurotransmitter exocytosis.
Slovenian: To vezavno mesto je sinaptični vezikularni protein 2A, ki naj bi bil udeležen pri fuziji veziklov in eksocitozi nevrotransmiterjev.
English: Directions for the proper use of Levetiracetam Hospira is provided in section 3.
Slovenian: Navodila za pravilno uporabo zdravila Levetiracetam Hospira se nahajajo v poglavju 3.
English: Should your doctor decide to stop your Levetiracetam Hospira treatment, he/she will instruct you about the gradual withdrawal of Levetiracetam Hospira.
Slovenian: Če se bo vaš zdravnik odločil za prekinitev zdravljenja z zdravilom Levetiracetam Hospira, vam bo dal napotke o postopni ukinitvi zdravila Levetiracetam Hospira.
English: In vitro, levetiracetam and its primary metabolite have been shown not to inhibit the major human liver cytochrome P450 isoforms (CYP3A4, 2A6, 2C9, 2C19, 2D6, 2E1 and 1A2), glucuronyl transferase (UGT1A1 and UGT1A6) and epoxide hydroxylase activities.
Slovenian: In vitro so pokazali, da levetiracetam in njegov primarni presnovek ne zavirata aktivnosti glavnih izooblik človeškega jetrnega citokroma P450 (CYP3A4, 2A6, 2C9, 2C19, 2D6, 2E1 in 1A2), glukuronil-transferaze (UGT1A1 in UGT1A6) in epoksid-hidroksilaze.
English: General dose: between 1,000 mg and 3,000 mg each day.
Slovenian: Običajni odmerek: med 1.000 mg in 3.000 mg na dan.
English: If you stop using Levetiracetam Hospira:
Slovenian: Če ste prenehali uporabljati zdravilo Levetiracetam Hospira:
English: Since there was limited exposure for levetiracetam intravenous use and since oral and intravenous formulations are bioequivalent, the safety information of levetiracetam intravenous will rely on levetiracetam oral use.
Slovenian: Zaradi omejene izpostavljenosti intravenski uporabi levetiracetama in zaradi bioekvivalence med peroralno in intravensko obliko informacije o varnosti intravenske uporabe levetiracetama temeljijo na peroralni uporabi levetiracetama.
English: A small number of people being treated with antiepileptics such as Levetiracetam Hospira have had thoughts of harming or killing themselves.
Slovenian: pri majhnem številu bolnikov, ki so se zdravili z antiepileptiki, kot je zdravilo Levetiracetam Hospira, so se pojavile misli na samopoškodovanje ali samomor.
English: • sudden decrease in kidney function;
Slovenian: • nenadno zmanjšanje delovanja ledvic;
English: • uncontrollable muscle spasms affecting the head, torso and limbs, difficulty in controlling movements, hyperkinesia (hyperactivity);
Slovenian: • nekontrolirani mišični spazmi, ki prizadenejo glavo, trup in okončine, težave pri nadzoru gibanja, hiperkinezija (hiperaktivnost);
English: However, data suggested a 20% higher levetiracetam clearance in children taking enzyme-inducing antiepileptic medicinal products.
Slovenian: Vendar pa podatki nakazujejo, da je pri otrocih, ki jemljejo antiepileptična zdravila, ki inducirajo encime, povečan očistek levetiracetama za 20 %.
English: Levetiracetam induces seizure protection in a broad range of animal models of partial and primary generalised seizures without having a pro-convulsant effect.
Slovenian: Levetiracetam povzroči zaščito pred parcialnimi in primarno generaliziranimi napadi pri širokem spektru živalskih modelov in nima prokonvulzivnega učinka.
English: • weakness, feel light-headed or dizzy or have difficulty breathing, as these may be signs of a serious allergic (anaphylactic) reaction
Slovenian: • šibkost, vrtoglavico ali omotico ali težave z dihanjem, saj so to lahko znaki resne alergijske (anafilaktične) reakcije
English: To use this dosing table, an estimate of the patient's creatinine clearance (CLcr) in ml/min is needed.
Slovenian: Za uporabo te preglednice je treba predhodno oceniti bolnikov očistek kreatinina (CLcr) v ml/min.
English: The pharmacokinetic profile is linear with low intra- and inter-subject variability.
Slovenian: Ima linearni farmakokinetični profil, z majhno intra- in interindividualno variabilnostjo.
English: • rhabdomyolysis (breakdown of muscle tissue) and associated blood creatine phosphokinase increase.
Slovenian: • rabdomioliza (razgradnja mišičnega tkiva) in z njo povezano zvišanje kreatin fosfokinaze v krvi.
English: The intravenous formulation is an alternative to your oral administration.
Slovenian: Intravenska oblika je alternativa vaši peroralni uporabi.
English: In man, an activity in both partial and generalised epilepsy conditions (epileptiform discharge/photoparoxysmal response) has confirmed the broad spectrum pharmacological profile of levetiracetam.
Slovenian: Delovanje na parcialne in generalizirane epileptične napade (epileptiformno proženje/fotoparoksizmalen odgovor) potrjuje njegov širok spekter farmakološkega profila levetiracetama pri ljudeh.
English: A retrospective assessment of pharmacokinetic interactions in children and adolescents with epilepsy (4 to 17 years) confirmed that adjunctive therapy with orally administered levetiracetam did not influence the steady-state serum concentrations of concomitantly administered carbamazepine and valproate.
Slovenian: Retrospektivna ocena o farmakokinetičnih interakcijah pri otrocih in mladostnikih z epilepsijo (od 4 do 17 let) je potrdila, da dopolnilna terapija s peroralno uporabljenim levetiracetamom ni vplivala na koncentracije v serumu v stanju dinamičnega ravnovesja pri sočasnem dajanju karbamazepina in valproata.
English: The time independent pharmacokinetic profile of levetiracetam was also confirmed following 1,500 mg intravenous infusion for 4 days with twice daily dosing.
Slovenian: Potrjen je bil tudi časovno neodvisen farmakokinetični profil levetiracetama pri intravenski infuziji 1.500 mg dvakrat dnevno 4 dni.
English: The primary metabolite is inactive.
Slovenian: Njegov primarni presnovek ni aktiven.
English: What Levetiracetam Hospira is and what it is used for
Slovenian: Kaj je zdravilo Levetiracetam Hospira in za kaj ga uporabljamo
English: This is more likely at the beginning of treatment or after an increase in the dose.
Slovenian: Zaspanost se največkrat pojavlja na začetku zdravljenja ali po povečanju odmerka.
English: Two minor metabolites were also identified.
Slovenian: Odkrili so še dva manj pomembna presnovka.
English: 5 How to store Levetiracetam Hospira 6 Contents of the pack and other information
Slovenian: 5 Shranjevanje zdravila Levetiracetam Hospira 6 Vsebina pakiranja in dodatne informacije
English: The renal clearance of levetiracetam and ucb L057 is 0.6 and 4.2 ml/min/kg respectively indicating that levetiracetam is excreted by glomerular filtration with subsequent tubular reabsorption and that the primary metabolite is also excreted by active tubular secretion in addition to glomerular filtration.
Slovenian: Ledvični očistek levetiracetama 0,6 ml/min/kg in njegovega primarnega presnovka ucb L057 4,2 ml/min/kg kažeta na to, da se levetiracetam izloča z glomerulno filtracijo, ki ji sledi tubularna reabsorpcija, primarni presnovek pa se poleg glomerulne filtracije izloča tudi z aktivno tubularno sekrecijo.
English: • symptoms such as low urine volume, tiredness, nausea, vomiting, confusion and swelling in the legs, ankles or feet, as this may be a sign of sudden decrease of kidney function
Slovenian: • simptome kot so majhen volumen urina, utrujenost, slabost, bruhanje, zmedenost in otekanje nog, gležnjev ali stopal saj so lahko to znaki nenadnega zmanjšanja delovanja ledvic
English: In addition, levetiracetam does not affect the in vitro glucuronidation of valproic acid.
Slovenian: Levetiracetam in vitro prav tako ne vpliva na glukuronidacijo valprojske kisline.
English: Levetiracetam Hospira concentrate is for intravenous use only and the recommended dose must be diluted in at least 100 ml of a compatible diluent and administered intravenously as a 15-minute intravenous infusion (see section 6.6).
Slovenian: Zdravilo Levetiracetam Hospira koncentrat je samo za intravensko uporabo, priporočeni odmerek mora biti razredčen v vsaj 100 ml kompatibilnega topila in uporabljen intravensko kot 15-minutna intravenska infuzija (glejte poglavje 6.6).
English: At 3,600 mg/kg/day, in only one of the 2 EFD studies, there was a slight decrease in foetal weight associated with a marginal increase in skeletal variations/minor anomalies.
Slovenian: Pri 3.600 mg/kg/dan se je samo v eni od dveh študij embriofetalnega razvoja telesna masa plodu zanemarljivo zmanjšala v povezavi z marginalnim povečanjem skeletnih sprememb/manjših anomalij.
English: The active substance, levetiracetam, is a pyrrolidone derivative (S-enantiomer of α-ethyl-2-oxo-1-pyrrolidine acetamide), chemically unrelated to existing antiepileptic active substances.
Slovenian: Učinkovina levetiracetam je pirolidonski derivat (S-enantiomer -etil-2-okso-1-pirolidinacetamida), ki kemično ni podoben drugim antiepileptičnim učinkovinam.
English: Levetiracetam is not extensively metabolised in humans.
Slovenian: Levetiracetam se pri ljudeh ne presnavlja obsežno.
English: • a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome)
Slovenian: • široko razširjen izpuščaj z mehurji in luščenjem kože, še posebej okoli ust, nosu, oči in v predelu spolovil (Stevens-Johnsonov sindrom)
English: Do not use this medicine after the expiry date stated on the vial and carton box after EXP: The expiry date refers to the last day of the month.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na viali in škatli poleg oznake EXP:.
English: Levetiracetam Hospira is for intravenous use.
Slovenian: Zdravilo Levetiracetam Hospira je za intravensko uporabo.
English: What you need to know before you are given Levetiracetam Hospira
Slovenian: Kaj morate vedeti, preden boste prejeli zdravilo Levetiracetam Hospira
English: Peak plasma concentration was observed 0.5 to 1.0 hour after dosing.
Slovenian: Največja plazemska koncentracija je bila dosežena med 0,5 in 1 uro po odmerku.
English: It is therefore recommended to adjust the maintenance daily dose of levetiracetam, based on creatinine clearance in patients with moderate and severe renal impairment (see section 4.2).
Slovenian: Zato je priporočljivo dnevni vzdrževalni odmerek levetiracetama pri bolnikih z zmerno in hudo ledvično okvaro prilagoditi očistku kreatinina (glejte poglavje 4.2).
English: • skin rash, which may form blisters and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge) (erythema multiforme), a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form causing skin peeling in more than 30% of the body surface (toxic epidermal necrolysis);
Slovenian: • kožni izpuščaj, ki lahko tvori mehurčke in izgleda kot majhne tarče (na sredini temne pike, obkrožene s svetlejšim delom in s temnim krogom na robu) (multiformni eritem), široko razširjen izpuščaj z mehurčki in luščenjem kože, še posebej okoli ust, nosu, oči in v predelu spolovil (Stevens-Johnsonov sindrom) in bolj huda oblika, ki povzroči luščenje kože na več kot 30 % telesne površine (toksična epidermalna nekroliza);
English: 5 ml glass vial (type I) with bromobutyl coated rubber stoppers and an aluminium flip-off seal.
Slovenian: 5 ml steklena viala (tip I) z bromobutilnim gumijastim zamaškom in aluminijasto zaporko s ploščico.
English: • Sodium chloride 9 mg/ml (0.9%) solution for injection
Slovenian: • natrijev klorid 9 mg/ml (0,9 %) raztopina za injiciranje
English: The patients were randomized to carbamazepine CR 400-1,200 mg/day or levetiracetam 1,000-3,000 mg/day, the duration of the treatment was up to 121 weeks depending on the response.
Slovenian: Bolniki so randomizirano prejemali 400-1.200 mg karbamazepina z nadzorovanim sproščanjem (CR) na dan ali 1.000-3.000 mg levetiracetama na dan, trajanje zdravljenja pa je bilo do 121 tednov oziroma odvisno od odziva.
English: • a skin rash which may form blisters and look like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge) (erythema multiforme)
Slovenian: • kožni izpuščaj, ki lahko tvori mehurje in po videzu spominja na majhne tarče (na sredini temne pike, obkrožene s svetlejšim delom in s temnim krogom na robu) (multiformni eritem)
English: Each carton contains 10 or 25 vials.
Slovenian: Ena škatla vsebuje 10 ali 25 vial.
English: In paediatric patients (4 to 16 years of age), levetiracetam efficacy was established in a double-blind, placebo-controlled study, which included 198 patients and had a treatment duration of 14 weeks.
Slovenian: Pri pediatričnih bolnikih (od 4 do 16 let) je bila učinkovitost levetiracetama dokazana v dvojno slepi, s placebom nadzorovani študiji, ki je vključevala 198 bolnikov in trajala 14 tednov.
English: The adverse reaction profile presented below is based on the analysis of pooled placebo-controlled clinical trials with all indications studied, with a total of 3,416 patients treated with levetiracetam.
Slovenian: Profil neželenih učinkov, ki je opisan spodaj, temelji na analizi združenih s placebom nadzorovanih kliničnih preskušanj za vse preučevane indikacije, v katerih so z levetiracetamom zdravili 3416 bolnikov.
English: For children with renal impairment, levetiracetam dose needs to be adjusted based on the renal function as levetiracetam clearance is related to renal function.
Slovenian: Pri otrocih z ledvično okvaro je treba odmerek levetiracetama prilagoditi glede na delovanje ledvic, kajti z njihovim delovanjem je povezan tudi očistek levetiracetama.
English: • diplopia (double vision), vision blurred;
Slovenian: • diplopija (dvojni vid), zamegljen vid;
English: The dose level of 1800 mg/kg/day induced a marked maternal toxicity and a decrease in foetal weight associated with increased incidence of foetuses with cardiovascular/skeletal anomalies.
Slovenian: Odmerki 1.800 mg/kg/dan so sprožili izrazito toksičnost pri samicah in zmanjšanje telesne mase zarodka, povezano s povečanjem pogostnosti zarodkov s kardiovaskularnimi/skeletnimi anomalijami.
English: You can switch from the filmcoated tablets or from the oral solution to the intravenous formulation or reverse directly without dose adaptation.
Slovenian: Prehod od filmsko obloženih tablet ali od peroralne raztopine k intravenski obliki ali obratno, je lahko neposreden brez prilagajanja odmerka.
English: If you have any symptoms of depression and/or suicidal ideation, please contact your doctor.
Slovenian: Če imate kakršne koli simptome depresije ali misli o samomoru ali oboje, se posvetujte z zdravnikom.
English: Levetiracetam is an antiepileptic medicine (a medicine used to treat seizures (fits) in epilepsy).
Slovenian: Levetiracetam je zdravilo proti epilepsiji (zdravilo za zdravljenje epileptičnih napadov).
English: Breast-feeding is not recommended during treatment.
Slovenian: Med zdravljenjem ni priporočljivo dojiti.
English: For doctors and nurses, more detailed direction for the proper use of Levetiracetam Hospira is provided in section 6.
Slovenian: Za zdravnike in medicinske sestre so podrobna navodila za uporabo zdravila Levetiracetam Hospira navedena v poglavju 6.
English: Levetiracetam 1,000 mg daily did not influence the pharmacokinetics of oral contraceptives (ethinylestradiol and levonorgestrel); endocrine parameters (luteinizing hormone and progesterone) were not modified.
Slovenian: Levetiracetam v odmerku 1.000 mg na dan ni vplival na farmakokinetiko peroralnih kontraceptivov (etinilestradiola in levonorgestrela); endokrini parametri (luteinizirajoči hormon in progesteron) se niso spremenili.
English: However, based on the pharmacokinetic characteristics of levetiracetam, the pharmacokinetics in adults after intravenous administration and the pharmacokinetics in children after oral administration, the exposure (AUC) of levetiracetam is expected to be similar in paediatric patients aged 4 to 12 years after intravenous and oral administration.
Slovenian: Vendar je na osnovi farmakokinetičnih znaličnosti levetiracetama, farmakokinetike pri odraslih po intravenskem dajanju in farmakokinetike pri otrocih po peroralnem dajanju, pričakovati pri otrocih od 4 do 12 let podobno razpoložljivost (AUC) levetiracetama po intravenskem in peroralnem dajanju.
English: Vial of 5 ml
Slovenian: Viala s 5 ml
English: Dose in children 50 kg or greater is the same as in adults.
Slovenian: Pri otrocih, ki so težki 50 kg ali več, je odmerjanje enako kot pri odraslih.
English: • depression, hostility or aggression, anxiety, insomnia, nervousness or irritability;
Slovenian: • depresija, sovražnost ali agresivnost, anksioznost, nespečnost, živčnost ali razdražljivost;
English: • decreased blood sodium concentration;
Slovenian: • znižana koncentracija natrija v krvi;
English: Following repeated oral dose administration (20 to 60 mg/kg/day) to epileptic children (4 to 12 years), levetiracetam was rapidly absorbed.
Slovenian: Po uporabi večkratnih peroralnih odmerkov (od 20 do 60 mg/kg/dan) pri otrocih z epilepsijo (od 4 do 12 let) se je levetiracetam hitro absorbiral.
English: 58.3% of the levetiracetam treated patients and 23.3% of the patients on placebo had at least a 50% reduction in myoclonic seizure days per week.
Slovenian: 58,3 % bolnikov, ki so se zdravili z levetiracetamom, in 23,3 % bolnikov, ki so prejemali placebo, je imelo vsaj 50-odstotno zmanjšanje števila dni z miokloničnimi napadi na teden.
English: In the elderly, the half-life is increased by about 40% (10 to 11 hours).
Slovenian: Zaradi zmanjšanega delovanja ledvic se pri starejših razpolovni čas podaljša za približno 40 % (10 do 11 ur) (glejte poglavje 4.2).
English: In a pooled analysis, the percentage of patients who achieved 50% or greater reduction from baseline in the partial onset seizure frequency per week at stable dose (12/14 weeks) was of 27.7%, 31.6% and 41.3% for patients on 1,000, 2,000 or 3,000 mg levetiracetam respectively and of 12.6% for patients on placebo.
Slovenian: Delež bolnikov iz zbranih analiz, pri katerih je bilo doseženo 50 ali več odstotno zmanjšanje pogostnosti parcialnih napadov na teden pri stalnem odmerku (12/14 tednov), je bil 27,7 % pri bolnikih, ki so prejemali 1.000 mg, 31,6 % pri bolnikih, ki so prejemali 2.000 mg in 41,3 % pri bolnikih, ki so prejemali 3.000 mg levetiracetama, ter 12,6 % pri bolnikih, ki so prejemali placebo.