FrancophonIA/ELRC3.0 huggingface dataset:
English: • Changes in the way your heart beats (heart rhythm change) may occasionally happen.
Slovenian: • Občasno lahko pride do sprememb srčnega utripa (sprememba srčnega ritma).
English: As a result, greater peak to trough ratios are observed, however at recommended doses, geometric mean atazanavir exposures (Cmin, Cax and AUC) in paediatric patients are expected to be similar to those observed in adults.
Slovenian: Posledično so opažali večje razmerje med največjo in najmanjšo koncentracijo, vendar pa se pri priporočenih odmerkih pričakuje, da bo geometrična srednja izpostavljenost atazanavirju (Cmin, Cmax in AUC) pri pediatričnih bolnikih podobna kot pri odraslih.
English: The primary endpoint was the time-averaged difference in change from baseline in HIV RNA through 48 weeks (Table 6).
Slovenian: Primarni opazovani dogodek je bil povprečna časovna razlika v spremembi vrednosti HIV RNA po 48 tednih od izhodišča (preglednica 6).
English: Number of patients with paired genotypes classified as virological failures (HIV RNA ≥ 400 copies/ml).
Slovenian: Število bolnikov s pari genotipov, označenimi kot virusni neodziv (HIV RNA ≥ 400 kopij/ml).
English: Fifteen of 120 (13%) patients in the atazanavir + ritonavir treatment arm and 17 of 123 (14%) patients in the lopinavir + ritonavir arm had four or more of the PI substitutions L10, M46, I54, V82, I84, and L90.
Slovenian: Petnajst od 120 (13 %) bolnikov v skupini z atazanavirjem + ritonavirjem in 17 od 123 (14 %) bolnikov v skupini z lopinavirjem + ritonavirjem je imelo štiri ali več PI substitucij L10, M46, I54, V82, I84 in L90.
English: The signs may be a mild yellowing of the skin or eyes.
Slovenian: Znak je lahko blago rumeno obarvanje kože ali očesnih beločnic.
English: , angioedema a, urticaria, alopecia, pruritus; rare: Stevens-Johnson syndrome a,b
Slovenian: urtikarija, alopecija, pruritus; redki: Stevens-Johnsonov sindrom a,b
English: If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Slovenian: Če opazite kakršne koli simptome okužbe ali druge simptome, na primer mišično oslabelost, oslabelost, ki se najprej pojavi v dlaneh in stopalih in nato širi proti trupu, palpitacije, tremor ali hiperaktivnost, zaradi potrebnega zdravljenja nemudoma obvestite zdravnika.
English: In the majority of patients, a reduction in both voriconazole and atazanavir exposures are expected.
Slovenian: Pri večini bolnikov se pričakuje zmanjšanje izpostavljenosti tako vorikonazolu kot atazanavirju.
English: Atazanavir should not be used in combination with medicinal products that are substrates of CYP3A4 and have a narrow therapeutic index.
Slovenian: Atazanavirja se ne sme uporabljati skupaj z zdravili, ki so substrat za CYP3A4 in imajo ozek terapevtski indeks.
English: If necessary, monitor carbamazepine serum concentrations and adjust the dose accordingly.
Slovenian: Po potrebi je treba spremljati koncentracije karbamazepina v serumu in odmerek ustrezno prilagoditi.
English: • insomnia (difficulty sleeping)
Slovenian: • insomnia (nespečnost).
English: Week 48: -3% [-7.6%, 1.5%] Week 96: 2.2% [-2.3%, 6.7%] HIV RNA <50 copies/ml, % by Baseline Characteristic d
Slovenian: 48. teden: -3 % [-7,6 %; 1,5 %] 96. teden: 2,2 % [-2,3 %; 6,7 %] HIV RNA <50 kopij/ml, % glede na izhodiščne lastnosti d
English: Grade 3 or 4 elevation of total bilirubin was noted in 37% (6% Grade 4).
Slovenian: Zvišanje vrednosti celotnega bilirubina 3. ali 4. stopnje so zabeležili pri 37 % bolnikov (4. stopnje pri 6 % bolnikov).
English: Although this study presented some limitations (i.e., unbound drug concentrations not studied), results suggested that the atazanavir pharmacokinetic parameters were decreased by 30% to 50% in patients undergoing haemodialysis compared to patients with normal renal function.
Slovenian: Študija ima sicer nekaj omejitev (npr. ni vrednotila koncentracij nevezanega zdravila), vendar pa rezultati kažejo, da se v primerjavi z bolniki z normalnim delovanjem ledvic pri bolnikih, ki se zdravijo s hemodializo, farmakokinetični parametri atazanavirja zmanjšajo za 30 % do 50 %.
English: Patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities during combination antiretroviral therapy and should be monitored according to standard practice.
Slovenian: Pri bolnikih z že obstoječo okvaro jeter, vključno s kroničnim aktivnim hepatitisom, so med kombiniranim protiretrovirusnim zdravljenjem okvare jeter pogostejše, zato jih je treba nadzirati v skladu s standardno prakso.
English: Given that low dose ritonavir (100 mg twice daily) has been shown to have no significant effect on methadone concentrations, no interaction is expected if methadone is co-administered with atazanavir, based on these data.
Slovenian: Glede na to, da je bilo dokazano, da nizki odmerek ritonavirja (100 mg dvakrat na dan) nima pomembnega vpliva na koncentracije metadona, na osnovi teh podatkov pri sočasni uporabi metadona z atazanavirjem interakcij ne pričakujemo.
English: If atazanavir is coadministered with parenteral midazolam, it should be done in an intensive care unit (ICU) or similar setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.
Slovenian: Če se atazanavir uporablja skupaj s parenteralnim midazolamom, ga je treba uporabljati v enoti za intenzivno nego ali podobnih okoliščinah, ki zagotavljajo skrben klinični nadzor in možnost ustreznega zdravniškega ukrepanja v primeru pojava zavore dihanja in/ali podaljšane sedacije.
English: In some patients with advanced HIV infection (AIDS) and a history of opportunistic infection, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started.
Slovenian: Pri nekaterih bolnikih z napredovalo okužbo s HIV (AIDS) in z oportunistično okužbo v anamnezi se lahko kmalu po začetku anti-HIV zdravljenja pojavijo znaki in simptomi vnetja, povezani s prejšnjimi okužbami.
English: Patients with chronic hepatitis B or C and treated with combination antiretroviral therapy are at an increased risk for severe and potentially fatal hepatic adverse reactions.
Slovenian: Bolniki s kroničnim hepatitisom B ali C, ki dobivajo kombinirano protiretrovirusno zdravljenje, so zaradi okvare jeter v večji nevarnosti za hude in morda smrtno nevarne neželene učinke.
English: It is recommended that women infected with HIV do not breast-feed because the virus might be transmitted through the breast milk.
Slovenian: Ženskam, okuženim s HIV, ne priporočamo dojenja, zaradi možnosti prenosa virusa z mlekom.
English: A dose reduction of the glucocorticoid should be considered with close monitoring of local and systemic effects or a switch to a glucocorticoid, which is not a substrate for CYP3A4 (e.g., beclomethasone).
Slovenian: Razmisliti je treba o zmanjšanju odmerka glukokortikoida in skrbno nadzirati morebiten pojav lokalnih ali sistemskih učinkov ali glukokortikoid zamenjati s takšnim, ki ni substrat za CYP3A4 (npr. beklometazon).
English: The potential for PR prolongation should be considered in cases of overdose (see section 4.9).
Slovenian: V primerih prevelikega odmerjanja je treba upoštevati možnost podaljšanja intervala PR (glejte poglavje 4.9).
English: The safety and efficacy of atazanavir has not been established in patients with significant underlying liver disorders.
Slovenian: Varnost in učinkovitost atazanavirja nista raziskani pri bolnikih s pomembnimi osnovnimi boleznimi jeter.
English: Atazanavir binds to both alpha-1-acid glycoprotein (AAG) and albumin to a similar extent (89% and 86%, respectively, at 1,000 ng/ml).
Slovenian: Atazanavir se v podobni meri veže na alfa-1-kisli glikoprotein in na albumin (89 % na prvega in 86 % na drugega pri 1.000 ng/ml).
English: In the pre- and postnatal development assessment in rats, atazanavir produced a transient reduction in body weight in the offspring at a maternally toxic dose.
Slovenian: Med pred- in postnatalno oceno razvoja pri podganah je atazanavir povzročil prehodno zmanjšanje telesne mase mladičev pri maternalno toksičnih odmerkih.
English: • quetiapine (used to treat schizophrenia, bipolar disorder and major depressive disorder).
Slovenian: • kvetiapin (uporabljamo ga za zdravljenje shizofrenije, bipolarne motnje in hude depresije),
English: Paediatric patients (6 years to less than 18 years of age and weighing at least 15 kg): The dose of atazanavir capsules for paediatric patients is based on body weight as shown in Table 1 and should not exceed the recommended adult dose.
Slovenian: Pediatrični bolniki (stari od 6 do manj kot 18 let in s telesno maso najmanj 15 kg): Odmerek atazanavirja v obliki kapsul pri pediatričnih bolnikih temelji na njihovi telesni masi, kot prikazuje preglednica 1, in ne sme preseči priporočenega odmerka za odrasle.
English: As a general rule, it is recommended that HIV infected women not breast-feed their infants in order to avoid transmission of HIV.
Slovenian: Splošno priporočilo je, da ženske, okužene z virusom HIV, ne dojijo, da ne bi tako prišlo do prenosa virusa HIV.
English: • interstitial nephritis (kidney inflammation), haematuria (blood in the urine), proteinuria (excess protein in the urine), pollakiuria (increased frequency of urination)
Slovenian: • intersticijski nefritis (vnetje ledvic), hematurija (kri v urinu), proteinurija (presežek beljakovin v urinu), polakisurija (pogostejše uriniranje);
English: Ritonavir capsules, tablets or oral solution.
Slovenian: Ritonavir v obliki kapsul, tablet ali peroralne raztopine.
English: Following a possible decrease in atazanavir exposure during the second and third trimester, atazanavir exposures might increase during the first two months after delivery (see section 5.2).
Slovenian: Poporodno obdobje Po morebitnem zmanjšanju izpostavljenosti atazanavirju med drugim in tretjim trimesečjem nosečnosti, se lahko izpostavljenost atazanavirju poveča v prvih dveh mesecih po porodu (glejte poglavje 5.2).
English: Resistance levels to atazanavir ranged from 3.5- to 29-fold without evidence of phenotypic cross resistance to other PIs.
Slovenian: Raven odpornosti proti atazanavirju je segala od 3,5- do 29-kratne brez znakov fenotipske navzkrižne odpornosti proti drugim zaviralcem proteaz.
English: • It is not recommended to use atazanavir with ritonavir for pregnant patients who are receiving both tenofovir disoproxil and an H2-receptor antagonist.
Slovenian: • Uporaba atazanavirja z ritonavirjem ni priporočljiva pri nosečih bolnicah, ki prejemajo tako dizoproksiltenofovirat kot antagonist receptorjev H2.
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant Summary of Product Characteristics for these medicinal products (see section 4.8).
Slovenian: V primeru sočasnega zdravljenja hepatitisa B ali C je treba upoštevati povzetke glavnih značilnosti za uporabljena zdravila (glejte poglavje 4.8).
English: Increased plasma concentrations of quetiapine may lead to coma (see section 4.3).
Slovenian: Zvišane koncentracije kvetiapina v plazmi lahko povzročijo komo (glejte poglavje 4.3).
English: uncommon: hypertension
Slovenian: občasni: hipertenzija
English: • carbamazepine, phenytoin, phenobarbital, lamotrigine (antiepileptics)
Slovenian: • karbamazepin, fenitoin, fenobarbital in lamotrigin (antiepileptiki),
English: Manufacturer
Slovenian: Izdelovalci
English: This association was observed independently of exposure to tenofovir disoproxil.
Slovenian: To povezavo so opazili ne glede na izpostavljenost dizoproksiltenofoviratu.
English: Atazanavir given without ritonavir should not be used in pregnant patients given that it could result of suboptimal exposure of particular concern for the mother infection and vertical transmission.
Slovenian: Atazanavirja brez ritonavirja se ne sme uporabljati pri nosečnicah, saj možna suboptimalna izpostavljenost predstavlja pomembno tveganje za okužbo matere in vertikalni prenos.
English: Rashes are usually mild-to-moderate maculopapular skin eruptions that occur within the first 3 weeks of starting therapy with atazanavir.
Slovenian: Izpuščaji so običajno blagi do zmerni makulopapulozni izbruhi na koži, ki se lahko pojavijo v prvih 3 tednih po začetku zdravljenja z atazanavirjem.
English: Ten patients had baseline phenotypic resistance to atazanavir + ritonavir (fold change [FC]>5.2).
Slovenian: b Deset bolnikov je v izhodišču imelo fenotipsko odpornost na atazanavir + ritonavir (razmerje spremembe ('fold change' [FC]) >5,2).
English: The mechanism of interaction between atazanavir and tenofovir disoproxil fumarate is unknown.
Slovenian: Mehanizem interakcije med atazanavirjem in dizoproksiltenofovirijevim fumaratom ni znan.
English: Time-averaged difference ATV/RTV-LPV/RTV [97.5% CI
Slovenian: ATV/RTVLPV/RTV [97,5 % IZ
English: Switching to capsules from other formulations is encouraged as soon as patients are able to consistently swallow capsules.
Slovenian: Prehod z zdravljenja z drugimi farmacevtskimi oblikami zdravila na zdravljenje z zdravilom v obliki kapsul je priporočljiv takoj, ko lahko bolniki kapsule zanesljivo pogoltnejo.
English: Asymptomatic PR interval prolongation was more frequent in paediatric patients than adults.
Slovenian: Pri pediatričnih bolnikih je asimptomatsko podaljšanje intervala PR pogostejše kot pri odraslih bolnikih.
English: If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Slovenian: Če se pri takšnih bolnikih pojavijo znaki slabšanja bolezni jeter, je treba razmisliti o prekinitvi ali opustitvi zdravljenja.
English: uncommon: torsades de pointes a rare: QTc prolongation a, oedema, palpitation
Slovenian: občasni: torsade de pointes a; redki: podaljšanje intervala Q-Tc a, edem, palpitacije
English: Calcium channel blockers Bepridil
Slovenian: Zaviralci kalcijevih kanalčkov bepridil
English: • ketoconazole, itraconazole, and voriconazole (antifungals)
Slovenian: • ketokonazol, itrakonazol in vorikonazol (antimikotiki),
English: Antacids and medicinal products containing buffers
Slovenian: Antacidi antacidi in zdravila, ki vsebujejo pufre
English: Particular caution should be used when prescribing Atazanavir Mylan in association with medicinal products which have the potential to increase the QT interval and/or in patients with pre-existing risk factors (bradycardia, long congenital QT, electrolyte imbalances (see sections 4.8 and 5.3).
Slovenian: Posebna previdnost je potrebna pri predpisovanju zdravila Atazanavir Mylan skupaj z zdravili, ki lahko podaljšajo interval QT, in/ali pri bolnikih z že obstoječimi dejavniki tveganja (bradikardija, prirojeno podaljšanje intervala QT, neravnovesje elektrolitov) (glejte poglavji 4.8 in 5.3).
English: For co-administration of sildenafil for the treatment of erectile dysfunction see sections 4.4 and 4.5.
Slovenian: Glede sočasne uporabe sildenafila za zdravljenje erektilne disfunkcije glejte poglavji 4.4 in 4.5.
English: In long-term carcinogenicity studies of atazanavir in mice and rats, an increased incidence of benign hepatic adenomas was seen in female mice only.
Slovenian: V dolgoročnih študijah kancerogenosti pri miših in podganah so večjo incidenco benignih jetrnih adenomov odkrili samo pri mišjih samicah.
English: This co-administration might be considered on a case by case basis if deemed necessary, in patients with suppressed HIV viral loads and with HIV viral strain without any suspected resistance to the HIV regimen.
Slovenian: O sočasni uporabi, če je le-ta potrebna, je smiselno razmisliti pri vsakem posameznem bolniku z nadzorovanim bremenom virusa HIV in z okužbo s sevi virusa HIV, ki niso odporni na režim zdravljenja.
English: Based on data obtained with other boosted PIs and ketoconazole, where ketoconazole AUC showed a 3-fold increase, atazanavir/ritonavir is expected to increase ketoconazole or itraconazole concentrations.
Slovenian: Na osnovi podatkov, pridobljenih pri uporabi drugih okrepljenih zaviralcev proteaz in ketokonazola, kjer se je vrednost AUC ketokonazola povečala za 3krat, pri uporabi atazanavirja/ritonavirja pričakujemo, da se bodo koncentracije ketokonazola ali itrakonazola povečale.
English: In clinical studies AI424-397 and AI424-451, paediatric patients 3 months to less than 11 years of age had a mean duration of treatment with atazanavir oral powder of 80 weeks.
Slovenian: V kliničnih študijah AI424-397 in AI424-451 je zdravljenje pediatričnih bolnikov, starih od 3 mesece do manj kot 11 let, z atazanavirjem v obliki peroralnega praška v povprečju trajalo 80 tednov.
English: Some medicines may interact with ritonavir, a medicine that is taken with Atazanavir Mylan.
Slovenian: Nekatera zdravila lahko vplivajo na delovanje ritonavirja, zdravila, ki se jemlje skupaj z zdravilom Atazanavir Mylan.
English: Data from concomitant use of parenteral midazolam with other protease inhibitors suggest a possible 3-4 fold increase in midazolam plasma levels.
Slovenian: Podatki o sočasni uporabi parenteralnega midazolama z drugimi zaviralci proteaz kažejo, da se plazemske vrednosti midazolama lahko povečajo za 3- do 4-krat.
English: Co-administration with a high-fat meal did not affect the AUC of atazanavir relative to fasting conditions and the Cmax was within 11% of fasting values.
Slovenian: Uporaba skupaj z obrokom, bogatim z maščobami, ni vplivala na vrednost AUC atazanavirja v primerjavi z uporabo na tešče, vrednost Cmax pa je ostala znotraj 11 % vrednosti na tešče.
English: The efficacy of atazanavir/ritonavir in combination with tenofovir disoproxil fumarate in treatment-experienced patients has been demonstrated in clinical study 045 and in treatment naive patients in clinical study 138 (see sections 4.8 and 5.1).
Slovenian: Učinkovitost atazanavirja/ritonavirja v kombinaciji z dizoproksiltenofovirijevim fumaratom pri predhodno že zdravljenih bolnikih je bila dokazana v klinični študiji 045, pri predhodno še nezdravljenih bolnikih pa v klinični študiji 138 (glejte poglavji 4.8 in 5.1).
English: Desacetyl-diltiazem Cmax ↑172%
Slovenian: dezacetil-diltiazem Cmax ↑172 %
English: The withdrawal of ritonavir from the boosted regimen of atazanavir is not recommended, but may be considered in adults patients at the dose of 400 mg once daily with food only under the following combined restrictive conditions:
Slovenian: Odtegnitev ritonavirja iz okrepljenega režima zdravljenja z atazanavirjem ni priporočljiva, se pa o njej lahko razmisli pri odraslih bolnikih pri uporabi odmerka 400 mg enkrat na dan skupaj s hrano, vendar le ob upoštevanju vseh naslednjih omejitvenih pogojev:
English: Atazanavir exhibits anti- HIV-1 (including all clades tested) and anti-HIV-2 activity in cell culture.
Slovenian: Atazanavir na celičnih kulturah kaže anti-HIV-1 aktivnost (vključno z vsemi testiranimi sevi) in antiHIV-2 aktivnost.
English: [95% CI]
Slovenian: [95 % interval zaupanja]
English: PULMONARY ARTERIAL HYPERTENSION PDE5 Inhibitors
Slovenian: PLJUČNA ARTERIJSKA HIPERTENZIJA Zaviralci PDE5 sildenafil
English: The frequency of treatment emergent hepatitis or transaminase elevations in co-infected patients was comparable between atazanavir and comparator regimens (see section 4.4).
Slovenian: Pogostnost med zdravljenjem nastalega hepatitisa ali zvišanja transaminaz pri sočasno okuženih bolnikih je bila primerljiva med atazanavirjem in primerjalnimi shemami (glejte poglavje 4.4).
English: There is a trend toward a higher clearance in younger children when normalised for body weight.
Slovenian: Pri normalizaciji na telesno maso se pri mlajših otrocih kaže trend k večjemu očistku zdravila.
English: If you notice any of these symptoms please inform your doctor.
Slovenian: Če opazite katerega koli od teh simptomov, obvestite zdravnika.
English: It is one of a group called protease inhibitors.
Slovenian: Spada v skupino zaviralcev proteaz.
English: Chronic kidney disease
Slovenian: Kronična ledvična bolezen
English: Some patients taking combination antiretroviral therapy may develop a bone disease called osteonecrosis (death of bone tissue caused by loss of blood supply to the bone).
Slovenian: Pri nekaterih bolnikih, ki jemljejo kombinirano protiretrovirusno zdravljenje, se lahko pojavi bolezen kosti, imenovana osteonekroza (odmiranje kostnega tkiva zaradi nezadostne prekrvitve kosti).
English: In addition to the opportunistic infections, autoimmune disorders (a condition that occurs when the immune system attacks healthy body tissue) may also occur after you start taking medicines for the treatment of your HIV infection.
Slovenian: Poleg oportunističnih okužb se lahko po začetku jemanja zdravil za zdravljenje okužbe s HIV pojavijo tudi avtoimunske bolezni (stanja, do katerih pride, ko imunski sistem napade zdravo telesno tkivo).
English: An initial dose reduction of diltiazem by 50% is recommended, with subsequent
Slovenian: Priporočamo začetno zmanjšanje odmerka diltiazema za 50 % ter kasnejše povečevanje odmerka v skladu s spremljanjem EKG.
English: Medicinal products by therapeutic area
Slovenian: Zdravila po terapevtskih področjih
English: Overall in this study, 182 paediatric patients (81 antiretroviral-naive and 101 antiretroviral-experienced) received once daily atazanavir (capsule or powder formulation), with or without ritonavir, in combination with two NRTIs.
Slovenian: Skupaj je v tej študiji 182 pediatričnih bolnikov (81 jih še ni prejemalo protiretrovirusnih zdravil, 101 bolnik pa je protiretrovirusna zdravila že jemal) prejemalo atazanavir enkrat na dan (v obliki kapsul ali praška), z ali brez ritonavirja, v kombinaciji z dvema NRTI-jema.
English: Efficacy data observed in the 41 paediatric patients aged 6 years to less than 18 years that received Atazanavir capsules with ritonavir are presented in Table 7.
Slovenian: Podatki o učinkovitosti zdravila pri 41 pediatričnih bolnikih, starih od 6 do manj kot 18 let, ki so prejemali kapsule atazanavirja skupaj z ritonavirjem, so predstavljeni v preglednici 7.
English: When transitioning between formulations, a change in dose may be needed.
Slovenian: Pri zamenjavi farmacevtskih oblik bo morda treba spremeniti odmerek.
English: Atazanavir + saquinavir was shown to be inferior to lopinavir + ritonavir.
Slovenian: Dokazano je bilo, da je kombinacija atazanavir + sakvinavir slabša od kombinacije lopinavir + ritonavir.
English: ≥ 200 cells/mm
Slovenian: ≥ 200 celic/mm
English: eczema, vasodilatation
Slovenian: ekcem, vazodilatacija
English: At high doses that lead to high drug exposures, jaundice due to indirect (unconjugated) hyperbilirubinaemia (without associated liver function test changes) or PR interval prolongations may be observed (see sections 4.4 and 4.8).
Slovenian: Pri velikih odmerkih, ki povzročijo veliko izpostavljenost zdravilu, se lahko pojavita zlatenica, ki je posledica indirektne (nekonjugirane) hiperbilirubinemije (brez spremljajočih sprememb testov jetrnih funkcij), ali podaljšanje intervala PR (glejte poglavji 4.4 in 4.8).
English: • absence of prior virologic failure
Slovenian: • odsotnost predhodnega virusnega neodziva,
English: Desacetyl-diltiazem AUC ↑165%
Slovenian: dezacetil-diltiazem AUC ↑165 %
English: Other marked clinical laboratory abnormalities (Grade 3 or 4) reported in ≥ 2% of patients receiving regimens containing atazanavir and one or more NRTIs included: elevated creatine kinase (7%), elevated alanine aminotransferase/serum glutamic-pyruvic transaminase (ALT/SGPT) (5%), low neutrophils (5%), elevated aspartate aminotransferase/serum glutamic-oxaloacetic transaminase (AST/SGOT) (3%), and elevated lipase (3%).
Slovenian: Druge izrazite patološke laboratorijske vrednosti (3. ali 4. stopnje), opisane pri ≥ 2 % bolnikih, ki so prejemali atazanavir in enega ali več NRTI-jev, so: zvišanje kreatin-kinaze (7 %), zvišanje alaninaminotransferaze/serumske glutamat-piruvat transaminaze (ALT/SGPT) (5 %), zmanjšanje števila nevtrofilcev (5 %), zvišanje aspartat-aminotransferaze/serumske glutamat-oksalacetat transaminaze (AST/SGOT) (3 %) in zvišanje lipaze (3 %).