FrancophonIA/ELRC3.0 huggingface dataset:
English: B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2) .
Slovenian: B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja zdravila je le s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
English: There is insufficient data to recommend a specific dose in patients with partial DPD activity as measured by specific test.
Slovenian: Na voljo ni dovolj podatkov, da bi pri bolnikih z delnim pomanjkanjem aktivnosti DPD, določenim s posebnim testom, lahko priporočili specifičen odmerek.
English: Capecitabine Teva may be used either alone or in combination with other medicines.
Slovenian: Zdravilo Kapecitabin Teva se lahko uporablja samostojno ali v kombinaciji z drugimi zdravili.
English: Creatinine clearance was found to influence the systemic exposure to 5'-DFUR (35% increase in AUC when creatinine clearance decreases by 50%) and to FBAL (114% increase in AUC when creatinine clearance decreases by 50%).
Slovenian: Kreatininski očistek je vplival na sistemsko izpostavljenost 5´-DFUR (35 % povečanje AUC, kreatininski očistek zmanjšan za 50 %) in FBAL (114 % povečanje AUC in padec kreatinskega očistka za 50 %).
English: The AUC0-∞ values in μg•h/ml were 7.75, 7.24, 24.6, 2.03 and 36.3.
Slovenian: Vrednosti AUC0-∞ v μg•h/ml so znašale 7,75; 7,24; 24,6; 2,03 in 36,3.
English: The dose of Capecitabine Teva is based on your body surface area.
Slovenian: Odmerek zdravila Kapecitabin Teva je določen glede na vašo telesno površino.
English: Table 9 Key efficacy results for the non-inferiority analysis of Study NO16967 PRIMARY ANALYSIS
Slovenian: Preglednica 9 Glavni rezultati o učinkovitosti za analizo ne-inferiornosti v študiji NO16967 OSNOVNA ANALIZA
English: It is therefore possible that Capecitabine Teva could affect your ability to drive a car or operate machines.
Slovenian: Zato je možno, da zdravilo Kapecitabin Teva lahko vpliva na vašo sposobnost za vožnjo in upravljanje strojev.
English: -2nd appearance -3rd appearance -4th appearance
Slovenian: -drugo pojavljanje -tretje pojavljanje -četrto pojavljanje
English: Your doctor may want you to take a combination of 150 mg and 500 mg tablets for each dose.
Slovenian: Zdravnik vam bo morda predpisal jemanje kombinacije 150-mg in 500-mg tablet pri vsakem odmerku.
English: For those toxicities considered by the treating physician to be unlikely to become serious or life-threatening, e.g. alopecia, altered taste, nail changes, treatment can be continued at the same dose without reduction or interruption.
Slovenian: Pri tistih toksičnostih, za katere lečeči zdravnik meni, da je malo verjetno, da bodo postale resne ali življenjsko ogrožujoče (na primer alopecija, spremembe okusa, spremembe nohtov), se lahko zdravljenje nadaljuje z enakim odmerkom brez zmanjšanja ali prekinitve.
English: Other side-effects seen in this setting are the following:
Slovenian: Ostali neželeni učinki pri takšni uporabi so naslednji:
English: Capecitabine Teva should be permanently discontinued in patients who experience a severe skin reaction during treatment.
Slovenian: Zdravilo Kapecitabin Teva je treba trajno ukiniti pri bolnikih, pri katerih se med zdravljenjem pojavi huda kožna reakcija.
English: Furthermore, Capecitabine Teva is used to prevent new occurrence of colon cancer after complete removal of the tumour by surgery.
Slovenian: Zdravilo Kapecitabin Teva se uporablja tudi za preprečevanje novega pojava raka debelega črevesa po kompletni odstranitvi tumorja z operacijo.
English: Contact your doctor immediately if you are concerned about any of the side effects or if you notice any additional side effects not listed in the leaflet (see section 4 Possible side effects).
Slovenian: Nemudoma obvestite zdravnika, če vas skrbi kateri koli od neželenih učinkov ali če opazite kateri koli dodatni neželeni učinek, ki ni naveden v tem navodilu (glejte poglavje 4.
English: Brivudine must not be administered concomitantly with capecitabine.
Slovenian: Brivudina ne smemo dajati sočasno s kapecitabinom.
English: • History of severe and unexpected reactions to fluoropyrimidine therapy,
Slovenian: • Hude ali nepričakovane reakcije na zdravljenje s fluoropirimidinom v preteklosti.
English: • pain in the joints, or in the limbs (extremities), chest or back
Slovenian: • bolečine v sklepih ali v okončinah (ekstremitetah), prsih ali hrbtu
English: No information is available on hepatic impairment due to cirrhosis or hepatitis.
Slovenian: O okvari jeter zaradi ciroze ali hepatitisa ni na voljo nobenih podatkov.
English: • pain or altered/abnormal sensation in the mouth, pain in the jaw
Slovenian: • bolečina ali spremenjen/nenormalen občutek v ustih, bolečine v čeljusti
English: These dose adjustment recommendations for renal impairment apply both to monotherapy and combination use (see also section “Elderly” below).
Slovenian: Priporočila glede prilagoditve odmerka pri ledvičnih okvarah veljajo tako za samostojno kot kombinirano zdravljenje (glejte tudi poglavje »Starejši« spodaj).
English: During a treatment cycle for those toxicities considered by the treating physician not to be related to capecitabine, capecitabine should be continued and the dose of the other medicinal product should be adjusted according to the appropriate Prescribing Information.
Slovenian: Med ciklom zdravljenja za tiste toksičnosti, ki po mnenju lečečega zdravnika niso povezane s kapecitabinom, je treba zdravljenje s kapecitabinom nadaljevati in odmerke ostalih zdravil prilagoditi v skladu z ustreznimi informacijami o odmerjanju.
English: If you take more Capecitabine Teva than you should If you take more Capecitabine Teva than you should, contact your doctor as soon as possible before taking the next dose.
Slovenian: Če ste vzeli večji odmerek zdravila Kapecitabin Teva, kot bi smeli Če ste vzeli večji odmerek zdravila Kapecitabin Teva kot bi smeli, obvestite svojega zdravnika, preden boste zaužili naslednji odmerek.
English: The capecitabine pivotal studies included females of childbearing potential and males only if they agreed to use an acceptable method of birth control to avoid pregnancy for the duration of the study and for a reasonable period thereafter.
Slovenian: V ključnih študijah s kapecitabinom so sodelovale ženske v rodni dobi in moški, če so se strinjali, da bodo uporabljali sprejemljivo metodo kontracepcije, da bi preprečili nosečnost v času študije in primernem obdobju po njej.
English: • hiccups, change in voice
Slovenian: • kolcanje, sprememba glasu
English: Capecitabine Teva can induce severe skin reactions such as Stevens-Johnson syndrome and Toxic Epidermal Necrolysis.
Slovenian: Zdravilo Kapecitabin Teva lahko izzove hude kožne reakcije, kot sta Stevens-Johnsonov sindrom in toksična epidermalna nekroliza.
English: • certain types of arrhythmia (including ventricular fibrillation, torsade de pointes, and bradycardia)
Slovenian: • določeni tipi aritmije (vključno z ventrikularno fibrilacijo, torsades de pointes in bradikardijo)
English: See also section “Do not take Capecitabine Teva”.
Slovenian: Glejte tudi poglavje “Ne jemljite zdravila Kapecitabin
English: The usual dose for adults is 1250 mg/m2 of body surface area taken two times daily (morning and evening).
Slovenian: Običajni odmerek za odrasle je 1.250 mg/m2 telesne površine dvakrat na dan (zjutraj in zvečer).
English: Capecitabine is not indicated in children and adolescents.
Slovenian: Otroci in mladostniki Kapecitabin ni indiciran za otroke in mladostnike.
English: Patients with baseline neutrophil counts of <1.5 x 109/L and/or thrombocyte counts of <100 x 109/L should not be treated with capecitabine.
Slovenian: Bolniki, ki imajo osnovno število neutrofilcev <1.5 x 109/L in/ali število trombocitov <100 x 109/L, ne smejo biti zdravljeni s kapecitabinom.
English: Deficiency of DPD may lead to increased toxicity of capecitabine (see section 4.3 and
Slovenian: Pomanjkanje DPD lahko vodi do povečane toksičnosti kapecitabina (glejte poglavji 4.3 in 4.4).
English: Although sensitivity analyses show that differences in regimen schedules and timing of tumor assessments impact the ontreatment PFS analysis, a full explanation for this result has not been found.
Slovenian: Čeprav je analiza občutljivosti pokazala, da na preživetje brez napredovanja bolezni ob zdravljenju vplivajo razlike med odmerjanji v shemah zdravljenja in čas ocene tumorja, popolne razlage tega rezultata niso našli.
English: Diabetes mellitus or electrolyte disturbances
Slovenian: Sladkorna bolezen ali elektrolitske motnje
English: LIST OF EXCIPIENTS Also contains lactose.
Slovenian: SEZNAM POMOŽNIH SNOVI Vsebuje tudi laktozo.
English: In addition to the ADRs described in tables 4 and 5, and based on the above pooled analysis from clinical safety data from 7 clinical trials, encephalopathy was also associated with the use of capecitabine monotherapy with an incidence of less than 0.1%.
Slovenian: Poleg neželenih učinkov, opisanih v preglednicah 4 in 5, in na podlagi zgoraj omenjene skupne analize iz kliničnih podatkov o varnosti iz sedmih kliničnih preskušanj, je bila tudi encefalopatija povezana s samostojno uporabo kapecitabina, in sicer z incidenco, manjšo kot 0,1 %.
English: For patients with partial DPD deficiency (such as those with heterozygous mutations in the DPYD gene) and where the benefits of Capecitabine Teva are considered to outweigh the risks (taking into account the suitability of an alternative non-fluoropyrimidine chemotherapeutic regimen), these patients must be treated with extreme caution and frequent monitoring with dose adjusment according to toxicity.
Slovenian: Bolnike z delnim pomanjkanjem DPD (kot so tisti s heterozigotnimi mutacijami v genu DPYD) za katere smatramo, da koristi zdravila Kapecitabin Teva odtehtajo tveganja (upoštevaje primernost druge ne-fluoropirimidinske sheme kemoterapije), je treba zdraviti izredno previdno in jih pogosto spremljati ter prilagoditi odmerek glede na toksičnost.
English: • In patients with severe hepatic impairment,
Slovenian: • Pri bolnikih s hudo jetrno okvaro.
English: Body temperature increased ** Based on the post-marketing experience, persistent or severe palmar-plantar erythrodysaesthesia syndrome can eventually lead to loss of fingerprints (see section 4.4)
Slovenian: ** Na podlagi izkušenj po prihodu zdravila na trg lahko vztrajen ali hud sindrom palmarno-plantarne eritrodisestezije sčasoma privede do izgube prstnih odtisov (glejte poglavje 4.4).
English: Patients with severe diarrhoea should be carefully monitored and given fluid and electrolyte replacement if they become dehydrated.
Slovenian: Bolnike, pri katerih se pojavi huda driska, je treba skrbno opazovati in jim v primeru dehidracije nadomeščati tekočino in elektrolite.
English: • problems with liver function (seen in blood tests) and increased blood bilirubin (excreted by the liver)
Slovenian: • težave z delovanjem jeter (vidno v krvnih testih) in povečanje bilirubina v krvi (izločenega iz jeter)
English: There are no studies in pregnant women using capecitabine; however, it should be assumed that capecitabine may cause foetal harm if administered to pregnant women.
Slovenian: Študij o jemanju kapecitabina pri nosečnicah niso opravili, vendar se predvideva, da lahko kapecitabin povzroči okvare ploda, če bi ga ženske jemale med nosečnostjo.
English: red iron oxide (E172).
Slovenian: (E172), rdeči železov oksid (E172).
English: Not applicable *According to the National Cancer Institute of Canada Clinical Trial Group (NCIC CTG) Common Toxicity Criteria (version 1) or the Common Terminology Criteria for Adverse Events (CTCAE) of the Cancer Therapy Evaluation Program, US National Cancer Institute, version 4.0.
Slovenian: Navedba smiselno ni potrebna *Po splošnih kriterijih toksičnosti (različica 1) skupine za klinične raziskave Kandskega nacionalnega inštituta za onkologijo (NCIC CTG) ali splošnih terminoloških kriterijih za neželene učinke (CTCAE) (različica 4) programa za ocenjevanje zdravljenja raka Ameriškega nacionalnega inštituta.
English: • In patients with severe renal impairment (creatinine clearance below 30 ml/min),
Slovenian: • Pri bolnikih s hudo ledvično okvaro (očistek kreatinina pod 30 ml/min).
English: Musculoskeletal stiffness, Muscular weakness
Slovenian: mišično-skeletna togost, mišična šibkost
English: PHARMACEUTICAL FORM AND CONTENTS 60 film-coated tablets
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 60 filmsko obloženih tablet
English: There was a small increase in plasma concentrations of capecitabine and one metabolite (5'-DFCR); there was no effect on the 3 major metabolites (5'-DFUR, 5-FU and FBAL).
Slovenian: V plazmi so opazili majhno povečanje koncentracij kapecitabina in enega presnovka (5´-DFCR); na preostale tri glavne presnovke (5´-DFUR, 5-FU in FBAL) pa ni vplival.
English: • severe skin reaction such as skin rash, ulceration and blistering which may involve ulcers of the mouth, nose, genitalia, hands, feet and eyes (red and swollen eyes)
Slovenian: • hude kožne reakcije, kot so kožni izpuščaj, razjede in mehurji, ki lahko vključujejo razjede v ustih, nosu, na spolovilih, rokah, nogah in v očeh (rdeče in zatekle oči)
English: Based on the population pharmacokinetic analysis, which included patients with a wide range of ages (27 to 86 years) and included 234 (46%) patients greater or equal to 65, age has no influence on the pharmacokinetics of 5'-DFUR and 5-FU.
Slovenian: Na osnovi podatkov populacijske farmakokinetične študije, ki je zajela bolnike z velikim razponom v letih (27 do 86 let) in 234 bolnikov (46 %), starih 65 let ali starejših, so ugotovili, da starost ne vpliva na farmakokinetiko 5´-DFUR in 5-FU.
English: In addition to the above, when capecitabine is used alone, very common side effects which may affect more than 1 in 10 people are: - abdominal pain - rash, dry or itchy skin - tiredness - loss of appetite (anorexia)
Slovenian: Poleg zgoraj omenjenih, se lahko, kadar se kapecitabin uporablja samostojno, zelo pogosto (pri več kot 1 od 10 bolnikov) pojavijo naslednji neželeni učinki: - bolečina v trebuhu, - izpuščaj, suha ali srbeča koža, - utrujenost, - izguba apetita (anoreksija).
English: Discontinue permanently or If physician deems it to be in the patient's best interest to continue, interrupt until resolved to grade 0-1
Slovenian: Če zdravnik meni, da je za bolnika najbolje nadaljevati, prekiniti, dokler ne doseže stopnje 0-1
English: • cold sores or other herpes infections
Slovenian: • mehurčke na ustnicah ali druge okužbe s herpesom
English: What Capecitabine Teva is and what it is used for
Slovenian: Kaj je zdravilo Kapecitabin Teva in za kaj ga uporabljamo
English: • irregular heartbeat and palpitations (arrhythmias), chest pain and heart attack (infarction)
Slovenian: • neobičajno bitje srca in palpitacije (aritmija), bolečine v prsnem košu in srčni napad (infarkt)
English: No significant differences occurred in the exposure to other metabolites (5'-DFCR, 5'-DFUR, and 5-FU).
Slovenian: Značilnih razlik v izpostavljenosti drugim presnovkom (5´-DFCR, 5´-DFUR in 5-FU) ni bilo.
English: Dihydropyrimidine dehydrogenase (DPD) deficiency Rarely, unexpected, severe toxicity (e.g. stomatitis, diarrhoea, mucosal inflammation, neutropenia and neurotoxicity) associated with 5-FU has been attributed to a deficiency of DPD activity.
Slovenian: Pomanjkanje dihidropirimidin dehidrogenaze (DPD) Redko, nepričakovano, hudo toksičnost (npr. stomatitis, diarejo, vnetje sluznic, nevtropenijo in nevrotoksičnost), povezano s 5-FU, pripisujemo pomanjkanju aktivnosti DPD.
English: Capecitabine is contraindicated in patients with severe renal impairment (creatinine clearance below 30 ml/min [Cockcroft and Gault] at baseline).
Slovenian: Kapecitabin je kontraindiciran pri bolnikih z resnimi okvarami ledvic (kreatinski očistek pod 30 ml/min [Cockcroft in Gault] v izhodišču).
English: • confusional state, panic attacks, depressed mood, decreased libido
Slovenian: • zmedenost, panični napadi, depresivno razpoloženje, zmanjšan libido
English: The overall objective response rates (investigator assessment) were 20% (first trial) and 25% (second trial).
Slovenian: Celotni objektivni odziv po oceni raziskovalca je bil v prvem preskušanju 20 %, v drugem pa 25 %.
English: • Stevens-Johnson syndrome: if you experience painful red or purplish rash that spreads and blisters and/or other lesions begin to appear in the mucous membrane (e.g. mouth and lips), in particular if you had before light sensitivity, infections of the respiratory system (e.g. bronchitis) and/or fever.
Slovenian: • Stevens-Johnsonov sindrom: če dobite boleč, rdeč ali škrlaten izpuščaj, ki se širi, ali se začnejo pojavljati mehurji in/ali druge poškodbe na sluznici (npr. v ustih in na ustnicah), še posebno, če ste bili občutljivi na svetlobo ali imeli okužbe dihal (npr. bronhitis) in/ali zvišano telesno temperaturo.
English: If you have an unrecognised DPD deficiency and take capecitabine, you are at an increased risk of acute early-onset of severe forms of the side effects listed under section 4 Possible side effects.
Slovenian: Če ne veste, da imate pomanjkanje DPD in vzamete kapecitabin, imate večje tveganje za nenaden, zgodnji pojav hudih oblik neželenih učinkov, navedenih v poglavju 4.
English: Table 6 Treatment regimens in study NO16966 (mCRC) Treatment
Slovenian: Preglednica 6 Sheme zdravljenja v študiji NO16966 (metastatski kolorektalni rak)
English: Also, you need to be particularly careful if you are taking any of the following: - gout medicines (allopurinol), - blood-thinning medicines (coumarin, warfarin), - medicines for seizures or tremors (phenytoin), - certain medicines used to treat various cancers or virus infection (interferon alpha), - radiotherapy and certain medicines used to treat cancer (folinic acid, oxaliplatin, bevacizumab,
Slovenian: Posebno previdni morate biti tudi pri jemanju naslednjih zdravil: - zdravil proti protinu (alopurinol), - zdravil proti strjevanju krvi (kumarini, varfarin), - zdravil za preprečevanje epileptičnih napadov ali tremorja (fenitoin), - določenih zdravil za zdravljenje različnih vrst raka ali virusne okužbe (interferona alfa), - pri radioterapiji in določenih zdravilih za zdravljenje raka (folinska kislina, oksaliplatin,
English: If the calculated creatinine clearance decreases during treatment to a value below 30 ml/min, Capecitabine Teva should be discontinued.
Slovenian: Če se izračunani kreatinski očistek med zdravljenjem zmanjša pod vrednost 30 ml/min, je treba zdravljenje z zdravilom Kapecitabin Teva prenehati.
English: What you need to know before you take Capecitabine Teva
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo Kapecitabin Teva
English: Caution must be exercised in patients with diabetes mellitus or electrolyte disturbances, as these may be aggravated during capecitabine treatment.
Slovenian: Pri bolnikih s sladkorno boleznijo ali elektrolitskimi motnjami je potrebna previdnost, ker se njihovo stanje med zdravljenjem s kapecitabinom lahko poslabša.
English: No clinically significant differences in exposure to capecitabine or its metabolites, free platinum or total platinum occurred when capecitabine was administered in combination with oxaliplatin or in combination with oxaliplatin and bevacizumab.
Slovenian: Klinično pomembnih razlik v izpostavljenosti kapecitabinu ali njegovim presnovkom, prosti platini ali celokupni platini, ni bilo, ko so kapecitabin dajali v kombinaciji z oksaliplatinom ali v kombinaciji z oksaliplatinom in bevacizumabom.
English: Hand-foot syndrome
Slovenian: Sindrom roka-noga
English: - first-line treatment of advanced gastric cancer in combination with a platinum-based regimen (see section 5.1).
Slovenian: - za prvo linijo zdravljenja napredovalega raka želodca v kombinaciji s shemo na osnovi platine (glejte poglavje 5.1).
English: When capecitabine was used in combination with other medicinal products, elderly patients (≥65 years) experienced more grade 3 and grade 4 adverse drug reactions, including those leading to discontinuation, compared to younger patients.
Slovenian: Kadar je bil kapecitabin uporabljen v kombinaciji z drugimi zdravili, so bolniki, starejši od 65 let imeli več neželenih učinkov stopnje 3 in 4, vključno z takimi, ki so vodili do prekinitev, v primerjavi z mlajšimi bolniki.
English: HR (97.5% CI)
Slovenian: Razmerje ogroženosti (97,5-% CI)
English: Discontinue permanently
Slovenian: Trajno prekiniti ali
English: There is some evidence that dexpanthenol is effective for hand-foot syndrome prophylaxis in patients treated with Capecitabine.
Slovenian: Obstajajo dokazi, da je dekspantenol učinkovit pri preprečevanju sindroma roka-noga pri bolnikih, zdravljenih z zdravilom Kapecitabin Teva.
English: Two examples are provided here: A person whose body weight is 64 kg and height is 1.64 m has a body surface area of 1.7 m2 and should take 4 tablets of 500 mg and 1 tablet of 150 mg two times daily.
Slovenian: Navedena sta dva primera: oseba, ki tehta 64 kg in je visoka 1,64 m, ima telesno površino 1,7 m in mora vzeti 4 tablete po 500 mg in 1 tableto po 150 mg dvakrat na dan.
English: Administration with food decreases the rate of capecitabine absorption, but only results in a minor effect on the AUC of 5'-DFUR, and on the AUC of the subsequent metabolite 5-FU.
Slovenian: Jemanje s hrano zmanjša hitrost absorpcije kapecitabina, kar pa ima le neznaten vpliv na AUC 5´-DFUR in na AUC presnovka 5-FU.
English: FOLFOX-4/FOLFOX-4+P/ FOLFOX-4+BV (EPP*: N=937; ITT**: N=1017)
Slovenian: FOLFOX-4/FOLFOX-4 + P/ FOLFOX-4 + BEVACIZUMAB (EPP*: N=937; ITT**: N=1.017)
English: • In patients with severe leukopenia, neutropenia, or thrombocytopenia,
Slovenian: • Pri bolnikih s hudo levkopenijo, nevtropenijo ali trombocitopenijo.
English: If the other medicinal product(s) have to be discontinued permanently, capecitabine treatment can be resumed when the requirements for restarting capecitabine are met.
Slovenian: Če je treba zdravljenje z drugim(i) zdravili trajno prekiniti, se lahko z zdravljenjem s kapecitabinom nadaljuje, ko so izpolnjeni vsi pogoji za ponovno zdravljenje s kapecitabinom.
English: • inflammation of the veins (thrombophlebitis)
Slovenian: • vnetje ven (tromboflebitis)
English: Patients taking capecitabine should be informed of the need to interrupt treatment immediately if moderate or severe toxicity occurs.
Slovenian: Bolnike, ki prejemajo kapecitabin, je treba obvestiti, da je zdravljenje v primeru zmernih ali resnih toksičnosti treba opustiti.
English: Your doctor may instruct you to restart treatment at a lower dose.
Slovenian: Morda vam bo predpisal, da po prekinitvi nadaljujete zdravljenje z manjšimi odmerki.
English: Table 5 lists ADRs associated with the use of capecitabine in combination with different chemotherapy regimens in multiple indications based on safety data from over 3000 patients.
Slovenian: Preglednica 5 našteva neželene učinke, povezane z uporabo kapecitabina v kombinaciji z različnimi kemoterapijami pri več indikacijah, ki temeljijo na podatkih o varnosti, zbranih pri več kot 3.000 bolnikih.
English: • decrease in blood sodium, magnesium or calcium, increase in blood sugar
Slovenian: • znižanje natrija, magnezija ali kalcija v krvi, povišanje krvnega sladkorja,
English: There was no clinically significant effect of bevacizumab on the pharmacokinetic parameters of capecitabine or its metabolites in the presence of oxaliplatin.
Slovenian: Klinično pomembnega vpliva bevacizumaba na farmakakokinetične parametre kapecitabina ali njegovih presnovkov v prisotnosti oksaliplatina ni bilo.