FrancophonIA/ELRC3.0 huggingface dataset:
English: Sodium hydroxide (NaOH) (for pH adjustment) Water for injections
Croatian: 6.1 Popis pomoćnih tvari manitol citratna kiselina natrijev hidroksid (NaOH) (za podešavanje pH) voda za injekcije
English: Using aseptic technique, withdraw all of the diluted solution using an appropriate sterile needle (slightly incline the vial to ease withdrawal) (Figure 5) and discard the needle after withdrawal of the vial contents.
Croatian: 6. Primjenom aseptičke tehnike, izvucite svu razrijeđenu otopinu koristeći prikladnu sterilnu iglu (malo nagnite bočicu radi lakšeg izvlačenja sadržaja) (Slika 5) te nakon izvlačenja sadržaja iz bočice, iglu bacite.
English: Each vial contains 0.5 mg of ocriplasmin* in 0.2 mL solution.
Croatian: Jedna bočica sadržava 0,5 mg okriplazmina* u 0,2 ml otopine.
English: Ocriplasmin
Croatian: FARMACEUTSKI
English: JETREA 0.375 mg/0.3 mL solution for injection
Croatian: JETREA 0.375 mg/0.3 ml otopina za injekciju
English: Eye disorders
Croatian: Makularna rupa
English: Using aseptic technique, withdraw all of the solution using an appropriate sterile needle (slightly incline the vial to ease withdrawal) (Figure 3) and discard the needle after withdrawal of the vial contents.
Croatian: Primjenom aseptičke tehnike, izvucite svu otopinu koristeći prikladnu sterilnu iglu (malo nagnite bočicu radi lakšeg izvlačenja sadržaja) (Slika 3) te nakon izvlačenja sadržaja iz bočice, iglu bacite.
English: Repeated administration
Croatian: - pojačano suzenje
English: Once completely thawed, remove the protective orange polypropylene flip-off cap from the vial.
Croatian: Nakon potpunog odmrzavanja, skinite zaštitnu narančastu polipropilensku flip-off kapicu s bočice.
English: JETREA 0.375 mg/0.3 mL solution for injection ocriplasmin
Croatian: JETREA 0,375 mg/0,3 ml otopina za injekciju okriplazmin
English: Once completely thawed, remove the protective blue polypropylene flip-off cap from the vial.
Croatian: Nakon potpunog odmrzavanja, skinite zaštitnu plavu polipropilensku flip-flap kapicu s bočice.
English: Using aseptic technique, withdraw all of the diluted solution using an appropriate sterile needle (slightly incline the vial to ease withdrawal) and discard the needle after withdrawal of the vial contents.
Croatian: Primjenom aseptičke tehnike, izvucite svu razrijeđenu otopinu, koristeći prikladnu sterilnu iglu (malo nagnite bočicu radi lakšeg izvlačenja) te nakon izvlačenja sadržaja bočice iglu bacite.
English: JETREA 0.375 mg/0.3 mL injection ocriplasmin
Croatian: JETREA 0,375 mg/0,3 ml injekcija okriplazmin
English: 1 vial contains 0.5 mg ocriplasmin.
Croatian: NAVOĐENJE DJELATNE(IH) TVARI 1 bočica sadržava 0,5 mg okriplazmina.
English: Discard the vial and any unused portion of the diluted solution after single use.
Croatian: Nakon jednokratne primjene bacite bočicu i preostali neiskorišteni dio razrijeđene otopine.
English: Once completely thawed, remove the protective orange polypropylene flip-off cap from the vial
Croatian: Nakon potpunog odmrzavanja s bočice skinite zaštitnu narančastu polipropilensku flip-off kapicu
English: A higher proportion of JETREA treated patients gained ≥ 2 or ≥ 3 lines in BCVA (irrespective of vitrectomy) at Month 6 (28.0% and 12.3%, respectively) compared with patients treated with placebo
Croatian: Veći udio bolesnika liječenih JETREOM dobili su ≥ 2 ili ≥ 3 reda BCVA (bez obzira na vitrektomiju)
English: Solution for injection 1 vial
Croatian: Otopina za injekciju
English: Talk to your doctor/ophthalmologist if you develop any of the additional side effects listed below:
Croatian: Molimo obratite se liječniku/oftalmologu ako razvijete koji od dodatnih niže navedenih simptoma: Vrlo česte nuspojave (mogu se pojaviti u više od 1 na 10 bolesnika):
English: Discussion of the data available
Croatian: Rasprava dostupnih podataka
English: Any unnecessary exposure should be avoided.
Croatian: Treba izbjegavati svako nepotrebno izlaganje.
English: Do not use colistin as a substitute for good management practices.
Croatian: Ne koristite kolistin kao zamjenu za dobru praksu upravljanja.
English: There is no current scientifically well founded justification for the different treatment periods available.
Croatian: Ne postoji aktualno znanstveno dobro utemeljeno opravdanje za dostupna različita razdoblja terapije.
English: Hungary Biopol Fejlesztő és Kereskedelmi Kft.
Croatian: Mađarska Biopol Fejlesztő és Kereskedelmi Kft.
English: Str. Principala nr. 944, Filipestii de Padure , Jud.
Croatian: Principala nr. 944, Filipestii de Padure , Jud.
English: Next to that, treatment of subclinical Salmonella infections with the objective to reduce the number of bacteria might interfere with control programmes (e.g. Regulation 1177/2006; EFSA, 20105) for this disease.
Croatian: Osim toga, liječenje subkliničkih infekcija Salmonella sa ciljem smanjivanja broja bakterija može interferirati s kontrolnim programima (primjerice Uredba 1177/2006; EFSA, 20105) za ovu bolest.
English: This is in line with the previous assessment of the CVMP and the scientific advice to the European Commission.
Croatian: Ovo je u skladu s prethodnom ocjenom CVMP-a i znanstvenim savjetom Europske komisije.
English: Netherlands Eurovet Animal Health BV Postbus 179,
Croatian: Nizozemska Eurovet Animal Health BV Postbus 179,
English: 683 23 Ivanovice na Hané Czech Republic
Croatian: 683 23 Ivanovice na Hané Češka Republika
English: Following a request from the European Commission (EC), in July 2013 the CVMP and CHMP adopted scientific advice and detailed considerations on colistin1.
Croatian: Po zahtjevu Europske Komisije (EK), u srpnju 2013. CVMP i CHMP usvojili su znanstveni savjet i detaljnija razmatranja o kolistinu1.
English: Pol. Industrial El Segre P. 410 25191
Croatian: Industrial El Segre P. 410 25191
English: Colistin should not be used for the control of salmonellosis since it is not in line with control programmes for this disease and may present a risk to public and animal health.
Croatian: Kolistin se ne smije koristiti za kontrolu salmoneloze budući da nije u skladu s kontrolnim programima za ovu bolest i može predstavljati rizik za javno i životinjsko zdravstvo.
English: EFSA Panel on Biological Hazards; Scientific Opinion on a Quantitative Microbiological Risk Assessment of Salmonella in slaughter and breeder pigs In EFSA Journal.
Croatian: EFSA Panel on Biological Hazards; Scientific Opinion on a Quantitative Microbiological Risk Assessment of Salmonella in slaughter and breeder pigs In EFSA
English: Oral powder, white to almost white powder
Croatian: Oralni prašak, bijeli do gotovo bijeli prašak
English: Responsible use principles
Croatian: Načela odgovorne primjene
English: This group of antibiotics has a polypeptide structure, with mainly bactericidal activity and a medium antibacterial spectrum, which covers Gram-negative microorganisms only.
Croatian: Ova grupa antibiotika ima polipeptidnu strukturu, s uglavnom bakterijskim djelovanjem i srednjim antibakterijskim spektrom koji pokriva samo gram-negativne mikroorganizme.
English: CEVA SALUD ANIMAL, S.A. Carabela La Niña nº 12 5ª planta
Croatian: Španjolska CEVA SALUD ANIMAL, S.A. Carabela La Niña nº 12 5ª planta
English: Adyliget, Pipitér u. 5., Hungary
Croatian: Adyliget, Pipitér u. 5., Mađarska
English: Treatment duration should not exceed 7 days.
Croatian: Trajanje terapije ne smije iznositi više od 7 dana.
English: Romania PASTEUR - Filiala Filipesti SRL
Croatian: Rumunjska PASTEUR - Filiala Filipesti SRL
English: In many cases the dose is recommended as 100 000 IU/kg for mammalians (non-poultry species), (range approximately 18 000 IU/kg to 250 000 IU/kg body weight), and of 75 000 IU/kg for poultry species (range approximately 19 200 IU/kg to 270 000 IU/kg body weight.
Croatian: U mnogim slučajevima preporučena je doza od 100 000 IU/kg za sisavce (vrste koje nisu perad), (raspon od otprilike 18 000 IU/kg do 250 000 IU/kg tjelesne mase), te od 75 000 IU/kg za vrste peradi (raspon od otprilike 19 200 IU/kg do 270 000 IU/kg tjelesne mase).
English: 96-100 Skierniewice Poland
Croatian: 96-100 Skierniewice Poljska
English: 3 000 000 IU Tablet
Croatian: 3 000 000 IU Tableta
English: Romania CEVA SANTE ANIMALE ROMANIA SRL
Croatian: Rumunjska CEVA SANTE ANIMALE RUMUNJSKA SRL
English: Hungary Chemifarma S.p.a, 47122 Forli,
Croatian: Mađarska Chemifarma S.p.a, 47122 Forli,
English: “Transfer of resistance either on mobile genetic elements (such as plasmids) between bacteria or from animals to humans has not been reported.”
Croatian: „Nema prijava o prijenosu rezistencije na mobilne genetičke elemente (poput plazmida) između bakterija ili sa životinja na ljude.”
English: Specific treatment recommendations shorter than 7 days should be maintained.
Croatian: Treba zadržati specifične preporuke za terapiju kraću od 7 dana.
English: Data from the last report of the EMA European Surveillance of Veterinary Antimicrobial Consumption (ESVAC)2 shows that polymixins (colistin) are used mostly in oral forms.
Croatian: Podaci dostupni iz posljednjeg izvještaja Europskog praćenja veterinarske potrošnje antimikrobika (ESVAC)2 pri EMA potvrđuju da se polimiksini (kolistin) koriste najčešće u oralnim oblicima.
English: In addition, further information in line with prudent use principles for antimicrobials should be added in the product literature.
Croatian: Nadalje, treba dodati dodatne informacije o načelima razumne primijene za antimikrobike u literaturu proizvoda.
English: Pharmacotherapeutic group: Intestinal antiinfectives, antibiotics ATCvet code: QA07AA10
Croatian: Farmakoterapijska grupa: Intestinalni antiinfektivni lijekovi, antibiotici ATCvet kod: QA07AA10
English: Some of the products included in the scope of this referral procedure are indicated for use in horses and, although not stated explicitly in the product literature, it is assumed that these products are used predominantly in foals.
Croatian: Pojedini proizvodi uključeni u predmet ovog postupka upućivanja su indicirani za uporabu u konja te, iako nije eksplicitno navedeno u literaturi proizvoda, pretpostavlja se da se ovi proizvodi uglavnom koriste u ždrjebadi.
English: V. del Commercio 28/30 41012 - Carpi (MO) Italy
Croatian: V. del Commercio 28/30 41012 - Carpi (MO) Italija
English: Netherlands Virbac Laboratories 1ere Avenue, 2065 m L.I.D.,
Croatian: Nizozemska Virbac Laboratories 1ere Avenue, 2065 m L.I.D.,
English: The use of colistin for prophylaxis does not comply with responsible use principles.
Croatian: Primjena kolistina za profilaksu ne udovoljava načelima odgovorne primjene.
English: 42010 - Rio Saliceto (RE) Italy
Croatian: 42010 - Rio Saliceto (RE) Italija
English: Animal species
Croatian: Životinske vrste
English: Thus, the use of colistin in horses is considered to present a serious risk in relation to target animal safety and is no longer supported.
Croatian: Stoga se smatra da primjena kolistina u konja predstavlja ozbiljan rizik s obzirom na sigurnu primjenu u ciljnih životinja, te više nije podržana.
English: About 54% of the products concerned by this procedure contain general indications, whilst the remaining 46% contain specific indications, mainly gastrointestinal infections caused by colistin sensitive Enterobacteriaceae (e.g. E. coli and Salmonella).
Croatian: Otprilike 54% proizvoda obuhvaćenih ovim postupkom sadrži općenite indikacije, dok preostalih 46% sadrži specifične indikacije, uglavnom gastrointestinalne infekcije uzrokovane Enterobacteriaceae (primjerice E. coli i Salmonella) osjetljivom na kolistin.
English: In conclusion the CVMP recommended to add advice in the SPC that the duration of treatment should be limited to the minimum time necessary for the treatment of the disease, and that treatment duration should not exceed 7 days.
Croatian: Zaključno, CVMP je preporučio dodavanje savjeta u SPC-u da trajanje terapije treba ograničiti na minimalno vrijeme potrebno za liječenje bolesti, a da trajanje liječenja ne smije premašiti 7 dana.
English: Bulgaria Zavet Kiril and Metodiy str. 5 Zavet 7330
Croatian: Bugarska Zavet Kiril and Metodiy str. 5 Zavet 7330
English: Nevertheless, it is recognised that repeated or frequent use of an antimicrobial of the same class increases the risk of resistance development and transmission of such resistances to humans cannot be excluded.
Croatian: Bez obzira na navedeno, prepoznato je kako ponovljena ili česta uporaba antimikrobika iste klase može povećati rizik od razvoja rezistencije, a ne može se isključiti prijenos takve rezistencije na ljude.
English: Via San Zeno, 99/A 25124 Brescia Italy
Croatian: Via San Zeno, 99/A 25124 Brescia Italija
English: Thus, any pathogens other than non-invasive E. coli that are typically not associated with non-invasive gastrointestinal infections, and/or associated with general infections should be taken out of the SPC.
Croatian: Stoga, bilo koji drugi patogeni osim neinvanzivne E. coli koji se tipično ne povezuju s neinvazivnim gastrointestinalnim infekcijama, i/ili se povezuju s općenitim infekcijama treba ukloniti iz SPC-a.
English: This advice critically reviews recent information on the use of colistin in food-producing animals in the EU, its effect on the development of resistance to this category of antimicrobial agents in bacterial species that are of importance for human and animal health, and the possible impact on human and animal health.
Croatian: Ovaj savjet daje kritički osvrt na najnovije informacije o primjeni kolistina u životinja koje se koriste u proizvodnji hrane u EU, njegovom djelovanju na razvoj rezistencije u ovoj kategoriji antimikrobnih sredstava koji su važni za ljudsko i životinjsko zdravlje, kao i moguće djelovanje na zdravlje ljudi i životinja.
English: Doxal Italia S.p.a. largo Donegani 2 20121 - Milano Italy
Croatian: Doxal Italia S.p.a. largo Donegani 2 20121 - Milano Italija
English: Zone d'activites du bois de teillay
Croatian: Francuska Deltavit Zone d'activites du bois de teillay
English: Netherlands A.A.-Vet Diergeneesmiddelen N.V., Loofklapper 6-8, 8256 SL Biddinghuizen, Netherlands
Croatian: Nizozemska A.A.-Vet Diergeneesmiddelen N.V., Loofklapper 6-8, 8256 SL Biddinghuizen, Nizozemska
English: Whenever possible, colistin should only be used based on susceptibility testing.
Croatian: Kada je to moguće, kolistin treba koristiti samo na temelju testiranja podložnosti.
English: Bulgaria Gabropharm OOD 16 Alei Vazrajdane str., app. 42
Croatian: Bugarska Gabropharm OOD 16 Alei Vazrajdane str., app. 42
English: Bulgaria Farma SIS OOD 4 San Stefano str.
Croatian: Bugarska Farma SIS OOD 4 San Stefano str.
English: The recommended treatment period is similar for poultry and non-poultry species, 3-5 days or 5-7 days for most products, but for some products the treatment period is up to 10-15 days.
Croatian: Preporučena razdoblja terapije su slična za vrste peradi i vrste koje nisu perad, 3-5 dana ili 5-7 dana za većinu proizvoda, no za pojedine proizvode razdoblje terapije iznosi 10-15 dana.
English: Laboratoires Biove 3 Rue De Lorraine 62510 Arques France
Croatian: Francuska Laboratoires Biove 3 Rue De Lorraine 62510 Arques
English: List of the names, pharmaceutical forms, strengths of the veterinary medicinal products, animal species, applicants/marketing authorisation holders in the Member States
Croatian: Popis naziva, farmaceutskih oblika, jačina veterinarskomedicinskog proizvoda, životinjskih vrsta, podnositelja zahtjeva/nositelja odobrenja u državama članica
English: In addition to the measures described above the CVMP recommended to include the following special precautions for use in animals in order to ensure responsible use of colistin in animals: “Do not use colistin as a substitute for good management practices.
Croatian: Uz prethodno opisane mjere, CVMP je preporučio uključivanje sljedećih specijalnih mjera opreza za primjenu u životinja kako bi se osigurala odgovorna primjena kolistina u životinja: „Ne koristite kolistin kao zamjenu za dobru praksu upravljanja.
English: Duration of treatment should be limited to the minimum time necessary for the treatment of the disease.
Croatian: Trajanje terapije treba ograničiti na minimalno vrijeme potrebno za liječenje bolesti.
English: 1ere Avenue 2065 M L I D 06516 Carros Cedex France
Croatian: Francuska VIRBAC 1ere Avenue 2065 M L I D 06516 Carros Cedex Francuska
English: The prophylactic use of colistin and any extended use that is not in line with good veterinary practice present a risk from resistance perspective and is not justifiable from a scientific point of view.
Croatian: Profilaktička primjena kolistina i bilo kakva produljena primjena koja nije u skladu s dobrom veterinarskom praksom predstavlja rizik sa stajališta rezistencije i ne može se opravdati sa znanstvenog stajališta.
English: Buckinghamshire, HP7 9FB United Kingdom
Croatian: Buckinghamshire, HP7 9FB Ujedinjena Kraljevina
English: Replace, where applicable, treatment recommendations which are extended beyond 7 days, or where no treatment duration recommendation is given, with the following statement:
Croatian: Zamijeniti, gdje je primjenjivo, preporuke za terapiju koja je dulja od 7 dana, ili u slučaju kada nije navedena preporuka za trajanje terapije, sljedećom izjavom:
English: Račianska 77, 81 02 Bratislava, Slovak Republic
Croatian: Račianska 77, 81 02 Bratislava, Slovačka Republika
English: The advice states:
Croatian: U savjetu se navodi sljedeće:
English: While in these cases colistin is not the only active substance, it is the sole antimicrobial in the product and therefore these products are included in the scope of this referral.
Croatian: Iako u ovim slučajevima kolistin nije jedina djelatna tvar, on je jedini antimikrobik u proizvodu i stoga su ovi proizvodi obuhvaćeni ovim postupkom upućivanjem.
English: D-85276 Pfaffenhofen Germany
Croatian: D-85276 Pfaffenhofen Njemačka
English: In addition, advice should be included in the SPC that the presence of the disease should be established in the group or herd before metaphylactic treatment.
Croatian: 6. Nadalje, savjet treba biti uključen u SPC tako da se prisutnost bolesti treba utvrditi u grupi ili stadu prije metafilaktičkog liječenja.
English: Add, to all products and amend where applicable:
Croatian: Dodati za sve proizvode i dopuniti gdje je primjenjivo:
English: 831 02 Bratislava, Slovak Republic
Croatian: 831 02 Bratislava, Slovačka Republika
English: Alvetra & Werfft GmbH Boltzmanngasse 11, 1090 Wien, Austria
Croatian: Alvetra & Werfft GmbH Boltzmanngasse 11, 1090 Wien, Austrija
English: 2 Intrarea Vagonetului, Bl.
Croatian: 2 Intrarea Vagonetului, Bl. 101,Ap.
English: Hence a maximum treatment period of 7 days would ensure sufficient efficacy in the treatment and metaphylaxis of enteric diseases associated with non-invasive E. coli and would also satisfy the requirement to avoid unnecessary exposure and thus reduce the risk of resistance development.
Croatian: Stoga maksimalno razdoblje terapije od 7 dana osiguralo bi dostatnu djelotvornost u terapiji i metafilaksi enteričnih bolesti povezanih s neinvazivnom E. coli, te bi se udovoljilo zahtjevima za izbjegavanje nepotrebnog izlaganja, a tako ujedno i smanjio rizik od razvoja rezistencije.
English: Slovenia Krka, d. d., Novo mesto,
Croatian: Slovenija Krka, d. d., Novo mesto,
English: Colistin exerts concentration-dependent activity against Gram-negative bacteria.
Croatian: Kolistin ima djelovanje ovisno o koncentracije protiv gram-negativnih bakterija.
English: The Committee for Medicinal Products for Veterinary Use (CVMP) was requested to give its opinion on the measures that need to be taken in order to ensure the prudent use of colistin in food-producing animals across the EU and to minimise potential risks with the use of the identified products; inter alia whether there is a need to include adequate indications and warnings on prudent use in the product information and/or restrict indications for the identified products taking into account the CVMP revised guideline on the SPC for antimicrobial products (EMEA/CVMP/SAGAM/383441/2005)3.
Croatian: Od Odbora za veterinarsko-medicinske proizvode (CVMP) zatraženo je da donese svoje mišljenje o mjerama potrebnima kako bi se osigurala sigurna primjena kolistina u životinja koje se koriste u proizvodnji hrane diljem EU te kako bi se smanjili potencijalni rizici vezani uz primjenu identificiranih proizvoda; inter alia postoji li potreba za uključivanjem primjerenih indikacija i upozorenja o razumnoj uporabi u informacijama o proizvodu i/ili ograničiti proizvode uzimajući u obzir revidirane smjernice CVMP-a o SPC-u za antimikrobike (EMEA/CVMP/SAGAM/383441/2005)3.
English: 47122 Forlì Italy
Croatian: 47122 Forlì Italija
English: Romania LAVET PHARMACEUTICALS LTD.
Croatian: Rumunjska LAVET PHARMACEUTICALS LTD.
English: Currently, there is no evidence of spread of colistin resistance from food-producing animals to human patients, or vice versa.”
Croatian: Trenutno, nema dokaza o širenju rezistencije na kolistin od životinja koje se koriste u proizvodnji hrane na ljudske bolesnike ili obratno.”
English: 150 mg/tablet
Croatian: 150 mg/Tableta Tableta
English: Romania S.C. ROMVAC COMPANY S.A.
Croatian: Rumunjska S.C. ROMVAC COMPANY S.A.
English: Colistin sulfate is a polypeptide antibiotic belonging to the polymyxin group of antibiotics.
Croatian: Kolistin sulfat je polipeptidni antibiotik koji se ubraja u grupu antibiotika polimiksina.
English: Special precautions for use in animals:
Croatian: Posebna upozorenja prilikom primjene na životinjama:
English: In line with responsible use principles the duration of treatment should be limited to the time needed for cure of the disease to avoid any unnecessary exposure.
Croatian: U skladu s odgovornim načelima primjene trajanje liječenja treba ograničiti na vrijeme potrebno za liječenje bolesti kako bi se izbjeglo bilo kakvo nepotrebno izlaganje.
English: The indication salmonellosis is no longer maintained and gastrointestinal infection caused by E. coli (colibacillosis) is not a recognised clinical disease in foals or adult horses.
Croatian: Indikacija salmoneloza više nije sadržana, a gastrointestinalna infekcija koju uzrokuje E. coli (kolibaciloza) nije priznata klinička bolest u ždrjebadi ili odraslih konja.
English: Add, to all products:
Croatian: Dodati za sve proizvode:
English: In addition, orally administered colistin would not be appropriate for systemic therapy due to poor absorption from the gastrointestinal tract.
Croatian: Nadalje, oralno primijenjen kolistin ne bi bio primjeren za sistemijsku terapiju uslijed slabe apsorpcije iz gastrointestinalnog trakta.
English: The advice also indicates for combinations of colistin with other antimicrobials that “The marketing authorisations for these products should be reviewed and unless sound justification can be provided that the combination is in line with responsible use principles, combination products should be withdrawn.”
Croatian: Dokaz, također, ukazuje na kombinaciju kolistina s drugim antimikrobicima da „Odobrenja za stavljanje VMP-a u promet za ove proizvode trebaju biti pregledani, te izuzev ako nije dostavljeno razumno opravdanje da je kombinacija u skladu s načelima, kombinirani proizvodi trebaju se povući iz prometa.”
English: There is no evidence at present that the use of colistin in food-producing species resulted in widespread colistin resistance and its transfer to humans.
Croatian: Trenutno ne postoje dokazi da je primjena kolistina u vrsta koje se koriste za proizvodnju hrane rezultirala širenjem rezistencije na kolistin i njegovim prijenosom na ljude.
English: Most of the colistin formulations concerned (approximately 90%) are for administration in feed or water for group or flock treatment and, consequently, most of the indications are for “treatment and prevention”, meaning a situation where clinically diseased animals and in-contact animals presumably in the incubation phase but not yet showing clinical signs are treated at the same time.
Croatian: Većina predmetnih koncentracija kolistina (otprilike 90%) predviđena je za primjenu u hrani ili vodi za terapiju grupe ili jata, i posljedično, većina indikacija glasi za „liječenje i prevenciju“, što označava situaciju kada se klinički bolesne životinje i životinje u kontaktu nalaze najvjerojatnije u inkubacijskoj fazi no još uvijek ne pokazuju kliničke znakove pa se liječe istovremeno.