FrancophonIA/ELRC3.0 huggingface dataset:
English: The patients had at least one additional coronary heart disease risk factor, including: previous myocardial infarction or stroke (>6 months prior to enrollment) or documentation of other atherosclerotic cardiovascular disease (overall 51.5%), type 2 diabetes (36.1%), high density lipoprotein - cholesterol <35 mg/dl or <0.906 mmol/l (11.6%), left ventricular hypertrophy diagnosed by electrocardiogram or echocardiography (20.9%), current cigarette smoking (21.9%).
Danish: Patienterne havde mindst én ekstra risikofaktor for koronar hjertelidelse fx tidligere myokardieinfarkt eller apopleksi (>6 måneder før inkludering) eller dokumenteret anden aterosklerotisk kardiovaskulær sygdom (tilsammen 51,5 %), type 2-diabetes (36,1 %), HDL-kolesterol <35 mg/dl (<0,906 mmol/l) (11,6 %), venstre ventrikel-hypertrofi diagnosticeret ved elektrokardiogram eller ekkokardiografi (20,9 %), aktuel cigaretrygning (21,9 %).
English: If patients taking Dafiro HCT suffer from dizziness, headache, fatigue or nausea the ability to react may be impaired.
Danish: Hos patienter, der tager Dafiro HCT, og som får bivirkninger som svimmelhed, hovedpine, træthed eller kvalme, kan reaktionsevnen blive påvirket.
English: The safety of Dafiro HCT has been evaluated at its maximum dose of 10 mg/320 mg/25 mg in one controlled short-term (8 weeks) clinical study with 2,271 patients, 582 of whom received valsartan in combination with amlodipine and hydrochlorothiazide.
Danish: Sikkerheden af Dafiro HCT er blevet vurderet ved den maksimale dosis på 10 mg/320 mg/25 mg i et kontrolleret, kortvarigt (8 uger) klinisk studie med 2.271 patienter, af hvilke 582 fik valsartan i kombination med amlodipin og hydrochlorthiazid.
English: • inflamed pancreas, which may cause severe abdominal and back pain accompanied with feeling of being very unwell
Danish: • betændelse i bugspytkirtlen, som kan give stærke smerter i maven og ryggen og få dig til at føle dig meget utilpas
English: Patients taking Dafiro HCT and driving vehicles or using machines should take into account that dizziness or weariness may occasionally occur.
Danish: Patienter, som fører motorkøretøj eller betjener maskiner under behandling med Dafiro HCT, skal være opmærksomme på, at der lejlighedsvis kan optræde svimmelhed eller træthed.
English: After oral administration of therapeutic doses of amlodipine alone, peak plasma concentrations of amlodipine are reached in 6-12 hours.
Danish: Efter oral administration af amlodipin alene i terapeutiske doser opnås maksimal plasmakoncentration af amlodipin efter 6-12 timer.
English: Frequency Dafiro HCT
Danish: Frekvens Dafiro HCT
English: • skin and lip cancer (non-melanoma skin cancer)
Danish: • hud- og læbekræft (non-melanom hudkræft)
English: • cholestyramine, colestipol or other resins (substances used mainly to treat high levels of lipids in the blood);
Danish: • colestyramin og colestipol eller andre ionbytterresiner (medicin, der primært bruges til behandling af forhøjet fedtniveau i blodet);
English: • swelling of the tongue and throat which causes great difficulty breathing
Danish: • hævelse af tunge eller svælg, hvilket kan gøre det meget svært at trække vejret
English: • medicines that may reduce the amount of potassium in your blood, such as diuretics (water tablets), corticosteroids, laxatives, amphotericin or penicillin G;
Danish: • medicin som kan nedsætte mængden af kalium i dit blod, som fx diuretika (vanddrivende tabletter), kortikosteroider, afføringsmidler, amphotericin eller benzylpenicillin;
English: • severe skin reactions including intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of the mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions
Danish: • alvorlige hudreaktioner, som indbefatter udbredt hududslæt, nældefeber, hudrødme over hele kroppen, intens kløe, blæredannelse, afskalning eller hævelse i huden, betændelseslignende tilstand i slimhinderne (Stevens-Johnsons syndrom, toksisk epidermal nekrolyse) eller andre allergiske reaktioner
English: High hydrochlorothiazide use (≥50000 mg cumulative) was associated with an adjusted odds ratio (OR) of 1.29 (95% CI: 1.23-1.35) for BCC and 3.98 (95% CI: 3.68-4.31) for SCC.
Danish: Stort forbrug af hydrochlorthiazid (≥50.000 mg kumulativt) var forbundet med en justeret odds ratio (OR)-værdi på 1,29 (95 % KI: 1,23-1,35) for basalcellekarcinom og på 3,98 (95 % KI: 3,68-4,31) for pladecellekarcinom.
English: Dafiro HCT tablets contain three substances called amlodipine, valsartan and hydrochlorothiazide.
Danish: Dafiro HCT tabletter indeholder tre stoffer, som kaldes amlodipin, valsartan og hydrochlorthiazid.
English: Following oral administration of valsartan alone, peak plasma concentrations of valsartan are reached in 2-4 hours.
Danish: Efter oral administration af valsartan alene opnås valsartans maksimale plasmakoncentration efter 2-4 timer.
English: When Dafiro HCT is used in patients with renal impairment periodic monitoring of serum electrolytes (including potassium), creatinine and uric acid serum levels is recommended.
Danish: Når Dafiro HCT anvendes hos patienter med nedsat nyrefunktion, anbefales regelmæssig monitorering af serumelektrolytter herunder kalium, samt serum-kreatinin og serum-urinsyre.
English: Amlodipine, valsartan and hydrochlorothiazide exhibit linear pharmacokinetics.
Danish: Amlodipin, valsartan og hydrochlorthiazid udviser lineær farmakokinetik.
English: Valsartan Inhibitors of the uptake transporter (rifampicin, ciclosporin) or efflux transporter (ritonavir)
Danish: Hæmmere af optagelsestransportøren (rifampicin, ciclosporin) eller effluxtransportøren (ritonavir)
English: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with ACE inhibitors, angiotensin II receptor antagonists including valsartan or thiazides.
Danish: Der er rapporteret reversibelt forhøjede serumkoncentrationer og toksicitet af lithium ved administration af lithium sammen med angiotensinkonverteringsenzym (ACE)-hæmmere, angiotensin IIantagonister inklusive valsartan eller thiazider.
English: if you have or have had heart failure or coronary artery disease, particularly if you are prescribed the maximum dose of Dafiro HCT (10 mg/320 mg/25 mg).
Danish: - hvis du har eller har haft hjertevigt eller sygdom i kranspulsåren, specielt hvis du får ordineret den højeste dosis af Dafiro HCT (10 mg/320 mg/25 mg).
English: There is evidence that the concomitant use of ACE inhibitors, ARBs or aliskiren increases the risk of hypotension, hyperkalaemia, and decreased renal function (including acute renal failure).
Danish: Der er tegn på, at samtidig brug af ACE-hæmmere og ARBer eller aliskiren øger risikoen for hypotension, hyperkaliæmi og nedsat nyrefunktion (inklusive akut nyresvigt).
English: The mode of action of thiazides is through inhibition of the Na
Danish: Thiaziders virkningsmåde er gennem hæmning af Na
English: However, there was no significant difference in all-cause mortality between amlodipine-based therapy and chlorthalidone-based therapy RR 0.96 95% CI [0.89-1.02] p=0.20.
Danish: Der var dog ingen signifikant forskel på mortalitet af alle årsager mellem amlodipin-baseret behandling og chlorthalidon-baseret behandling, RR 0,96; 95 % KI [0,89-1,02]; p=0,20.
English: if you experience dizziness and/or fainting during treatment with Dafiro HCT, tell your doctor as soon as possible.
Danish: - hvis du bliver svimmel og/eller besvimer under behandlingen med Dafiro HCT, skal du fortælle det til din læge med det samme.
English: Amlodipine dose recommendations have not been established in patients with mild to moderate hepatic impairment.
Danish: Amlodipindosis er ikke fastlagt til patienter med let til moderat nedsat leverfunktion.
English: Dafiro HCT individual component
Danish: Dafiro HCT enkelte komponenter
English: Lipids increased
Danish: Forhøjet lipidtal
English: No dose adjustment of Dafiro HCT is required for patients with mild to moderate renal impairment (GFR ≥30 ml/min/1.73 m
Danish: Dosisjustering er ikke nødvendig hos patienter med let til moderat nedsat nyrefunktion (GFR ≥30 ml/min/1,73 m
English: Vasculitis necrotising and toxic epidermal necrolysis
Danish: Nekrotiserende vaskulitis, toksisk epidermal nekrolyse
English: The maximum recommended dose of Dafiro HCT is 10 mg/320 mg/25 mg.
Danish: Den maksimalt anbefalede dosis af Dafiro HCT er 10 mg/320 mg/25 mg.
English: • anticonvulsant medicines and mood-stabilising medicines used to treat epilepsy and bipolar disorder (e.g. carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone);
Danish: • krampehæmmende og humørstabiliserende medicin, som bruges til behandling af epilepsi og bipolar sygdom (fx carbamazepin, phenobarbital, phenytoin, fosphenytoin, primidon);
English: No information is available regarding the use of valsartan during breast-feeding.
Danish: Der foreligger ingen dokumentation vedrørende brug af valsartan under amning.
English: • ciclosporin (a medicine used in transplantation to prevent organ rejection or for other conditions, e.g: rheumatoid arthritis or atopic dermatitis);
Danish: • ciclosporin (medicin, som bruges ved transplantation for at undgå afstødning af et organ eller bruges til behandling af andre tilstande, fx leddegigt eller eksem);
English: If excessive hypotension occurs with Dafiro HCT, the patient should be placed in the supine position and, if necessary, given an intravenous infusion of normal saline.
Danish: Hvis der forekommer udtalt hypotension med Dafiro HCT, skal patienten placeres i liggende rygstilling, og om nødvendigt skal der gives intravenøs infusion af isotonisk natriumchlorid.
English: If you have accidentally taken too many Dafiro HCT tablets, talk to a doctor immediately.You may require medical attention.
Danish: Hvis du ved et uheld har taget for mange Dafiro HCT-tabletter, skal du straks kontakte en læge.
English: Heart failure and coronary artery disease/post-myocardial infarction
Danish: Hjertesvigt og lidelser i kranspulsåren/post-myokardieinfarkt
English: Antidiabetic agents (e.g. insulin and oral antidiabetic agents)
Danish: Antidiabetika (fx insulin og orale midler)
English: There is limited experience with the use of Dafiro HCT, particulary at the maximum dose, in patients with heart failure and coronary artery disease.
Danish: Der er begrænset erfaring med brug af Dafiro HCT til patienter med hjertesvigt og lidelser i kranspulsåren, især med den maksimale dosis.
English: • medicines used for HIV/AIDS (e.g. ritonavir, indinavir, nelfinavir);
Danish: • medicin mod hiv/aids (fx ritonavir, indinavir, nelfinavir);
English: • alcohol, sleeping pills and anaesthetics (medicines allowing patients to undergo surgery and other procedures);
Danish: • alkohol, sovemedicin og narkosemedicin (medicin, der bruges ved operationer og andre procedurer);
English: • medicines used to treat fungal infections (e.g. ketoconazole, itraconazole);
Danish: • medicin til behandling af svampeinfektioner (fx ketoconazol, itraconazol);
English: In the 8-week controlled clinical study, changes in laboratory parameters observed with the combination of Dafiro HCT were minor and consistent with the pharmacological mechanism of action of the monotherapy agents.
Danish: Ændringerne i laboratorieværdier, som blev set i det kontrollerede kliniske studie af 8 ugers varighed, var små og i overensstemmelse med de farmakologiske virkningsmekanisme for komponenterne i monoterapi.
English: Non-depolarising skeletal muscle relaxants (e.g. tubocurarine)
Danish: Ikke-depolariserende muskelrelaksantia (fx tubocurarin)
English: • sudden wheeziness, chest pain, shortness of breath or difficulty breathing
Danish: • pludselig åndenød, brystsmerter, kortåndethed eller besvær med at trække vejret.
English: 56 x 1 film-coated tablet (unit dose) 98 x 1 film-coated tablet (unit dose) 280 x 1 film-coated tablet (unit dose)
Danish: 56 x 1 filmovertrukket tablet (enhedsdosis) 98 x 1 filmovertrukket tablet (enhedsdosis) 280 x 1 filmovertrukket tablet (enhedsdosis)
English: • anticholinergic agents (medicines used to treat a variety of disorders such as gastrointestinal cramps, urinary bladder spasm, asthma, motion sickness, muscular spasms, Parkinson's disease and as an aid to anaesthesia);
Danish: • antikolinerge stoffer (medicin, som bruges til at behandle forskellige sygdomme som fx gastrointestinale kramper, urinblærekramper, astma, transportsyge, muskelkramper, Parkinsons sygdom samt i forbindelse med narkose);
English: if the level of potassium or sodium in your blood is too low despite treatment to increase the potassium or sodium levels in your blood.
Danish: - hvis mængden af kalium eller natrium i dit blod er lavere end normalt, selvom du er i behandling for at øge mængden af kalium og natrium i dit blod.
English: Dafiro HCT is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is a newborn, or was born prematurely.
Danish: Hvis du ønsker at amme, kan din læge vælge en anden behandling til dig, især hvis dit barn er nyfødt eller født for tidligt.
English: The use of hydrochlorothiazide may also need to be reconsidered in patients who have experienced previous NMSC (see also section 4.8).
Danish: Det kan også være nødvendigt at genoverveje, om hydrochlorthiazid bør anvendes hos patienter, der tidligere har haft non-melanom hudkræft (se også pkt.
English: There was no significant difference in the primary endpoint between amlodipine-based therapy and chlorthalidone-based therapy: risk ratio (RR) 0.98 95% CI (0.90-1.07) p=0.65.
Danish: Der var ingen signifikant forskel mellem amlodipin-baseret behandling og chlorthalidon-baseret behandling på det primære endepunkt: Risikoratio (RR) 0,98; 95 % KI (0,90-1,07); p=0,65.
English: Two large randomised, controlled trials (ONTARGET [ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial] and VA NEPHRON-D [The Veterans Affairs Nephropathy in Diabetes]) have examined the use of the combination of an ACE inhibitor with an ARB.
Danish: Kombinationen af en ACE-hæmmer og en ARB er undersøgt i to store randomiserede, kontrollerede studier (ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial) og VA NEPHRON-D (The Veterans Affairs Nephropathy in Diabetes)).
English: if your doctor has told you that you have a narrowing of the valves in your heart (called “aortic or mitral stenosis”) or that the thickness of your heart muscle is abnormally increased (called “obstructive hypertrophic cardiomyopathy”).
Danish: - hvis din læge har fortalt dig, at du har en forsnævring af hjerteklappen (dette kaldes ”aorta- eller mitralklapstenose”) eller hvis du har en unormal fortykkelse af hjertemusklen (dette kaldes
English: In case severe or rapid hyponatraemia develops during Dafiro HCT therapy, the treatment should be discontinued until normalisation of natraemia.
Danish: Hvis svær eller pludselig hyponatriæmi opstår under behandling med Dafiro HCT, bør behandlingen seponeres, indtil natriumbalancen er normaliseret.
English: Hypersensitivity to the active substances, to other sulphonamide derivatives, to dihydropyridine derivatives, or to any of the excipients listed in section 6.1.
Danish: - Overfølsomhed over for de aktive stoffer, andre sulfonamidderivater, dihydropyridinderivater eller over for et eller flere af hjælpestofferne anført i pkt.
English: Treatment with Dafiro HCT should only start after correction of hypokalaemia and any coexisting hypomagnesaemia.
Danish: Behandling med Dafiro HCT bør kun påbegyndes efter korrektion af hypokaliæmi og eventuel samtidig forekommende hypomagnesiæmi.
English: The following adverse reactions, listed by MedDRA System Organ Class and frequency, concern Dafiro HCT (amlodipine/valsartan/HCT) and amlodipine, valsartan and HCT individually.
Danish: Følgende bivirkninger, som er opstillet efter systemorganklasser i henhold til MedDRA og hyppighed gælder for Dafiro HCT (amlodipin/valsartan/hydrochlorthiazid) og amlodipin, valsartan og HCT individuelt.
English: If hypokalaemia develops during hydrochlorothiazide therapy, Dafiro HCT should be discontinued until stable correction of the potassium balance.
Danish: Hvis hypokaliæmi opstår under behandling med hydrochlorthiazid, bør Dafiro HCT seponeres, indtil kaliumbalancen er genoprettet og stabil.
English: No formal interaction studies with other medicinal products have been performed with Dafiro HCT.
Danish: Der er ikke udført formelle interaktionsstudier af Dafiro HCT i kombination med andre lægemidler.
English: In non-clinical safety studies, high doses of valsartan (200 to 600 mg/kg body weight) caused in rats a reduction of red blood cell parameters (erythrocytes, haemoglobin, haematocrit) and evidence of changes in renal haemodynamics (slightly raised blood urea nitrogen, and renal tubular hyperplasia and basophilia in males).
Danish: I prækliniske sikkerhedsstudier med rotter forårsagede høje doser valsartan (200-600 mg/kg legemsvægt) reduktion af blodtal (erytrocytter, hæmoglobin og hæmatokritværdi) og tegn på ændringer i den renale hæmodynamik (lettere forhøjet carbamid samt renal tubulær hyperplasi og basofili hos hanner).
English: The reductions in systolic/diastolic blood pressure with Dafiro HCT were 7.6/5.0 mmHg greater than with valsartan/hydrochlorothiazide, 6.2/3.3 mmHg greater than with amlodipine/valsartan, and 8.2/5.3 mmHg greater than with amlodipine/hydrochlorothiazide.
Danish: Reduktionen i systolisk/diastolisk blodtryk med Dafiro HCT var 7,6/5,0 mmHg større end med valsartan/hydrochlorthiazid; 6,2/3,3 mmHg større end med, amlodipin/valsartan og 8,2/5,3 mmHg større end med amlodipin/hydrochlorthiazid.
English: Multipack: 280 (4 packs of 70x1) film-coated tablets.
Danish: Multipakning: 280 (4 pakninger med 70x1) filmovertrukne tabletter.
English: Very rare** Not known
Danish: Meget sjælden**
English: Administration of thiazide diuretics, including hydrochlorothiazide, with vitamin D or with calcium salts may potentiate the rise in serum calcium.
Danish: D-vitamin og calciumsalte Administration af thiaziddiuretika, herunder hydrochlorthiazid, sammen med D-vitamin eller calciumsalte kan forstærke stigningen i serumcalcium.
English: • medicines that may induce “torsades de pointes” (irregular heart beat), such as antiarrhythmics
Danish: • medicin, som kan medføre ”torsades de pointes” (uregelmæssig hjerterytme), som fx antiarytmika (medicin, som bruges til behandling af hjerteproblemer) og visse antipsykotika;
English: CYP3A4 inducers (anticonvulsant agents [e.g. carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone], rifampicin, Hypericum perforatum [St. John's wort])
Danish: CYP3A4-inducerende stoffer (antikrampemidler [fx carbamazepin, phenobarbital, phenytoin, fosphenytoin, primidon], rifampicin, perikon)
English: There are no clinical studies on fertility with Dafiro HCT.
Danish: Der er ikke udført fertilitetsstudier med Dafiro HCT.
English: In the controlled trial of Dafiro HCT, the counteracting effects of valsartan 320 mg and hydrochlorothiazide 25 mg on serum potassium approximately balanced each other in many patients.
Danish: De modsat rettede effekter af valsartan 320 mg og hydrochlorthiazid 25 mg på kaliumniveauet i serum balancerede næsten hinanden hos mange patienter i det kontrollerede studie.
English: At week 8, the mean reductions in systolic/diastolic blood pressure were 39.7/24.7 mmHg with Dafiro HCT, 32.0/19.7 mmHg with valsartan/hydrochlorothiazide, 33.5/21.5 mmHg with amlodipine/valsartan, and 31.5/19.5 mmHg with amlodipine/hydrochlorothiazide.
Danish: I uge 8 var gennemsnitsreduktionen i systolisk/diastolisk blodtryk 39,7/24,7 mmHg med Dafiro HCT; 32,0/19,7 mmHg med valsartan/hydrochlorthiazid; 33,5/21,5 mmHg med amlodipin/valsartan, og 31,5/19,5 mmHg med amlodipin/hydrochlorthiazid.
English: Dizziness postural, dizziness exertional
Danish: Postural svimmelhed, svimmelhed ved aktivitet
English: Iron oxide, yellow (E172)
Danish: Jernoxid, rød (E172)
English: Titanium dioxide (E171) Iron oxide, yellow (E172)
Danish: Titandioxid (E171)
English: This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of Dafiro HCT.
Danish: Det skyldes, at grapefrugt og grapefrugtjuice kan føre til en øget mængde af det aktive stof, amlodipin, i blodet.
English: A total of 2,271 patients with moderate to severe hypertension (mean baseline systolic/diastolic blood pressure was 170/107 mmHg) received treatments of amlodipine/valsartan/hydrochlorothiazide 10 mg/320 mg/25 mg, valsartan/hydrochlorothiazide 320 mg/25 mg, amlodipine/valsartan 10 mg/320 mg, or hydrochlorothiazide/amlodipine 25 mg/10 mg. At study initiation patients were assigned lower doses of their treatment combination and were titrated to their full treatment dose by week 2.
Danish: 2.271 patienter med moderat til svær hypertension (hvor middel baseline for systolisk/diastolisk blodtryk var 170/107 mmHg) fik behandling med amlodipin/valsartan/hydrochlorthiazid 10 mg/320 mg/25 mg, valsartan/hydrochlorthiazid 320 mg/25 mg, amlodipin/valsartan 10 mg/320 mg, eller hydrochlorthiazid/amlodipin 25 mg/10 mg. Ved studiestart blev patienterne tildelt lavere doser af deres behandlingskombination, hvorefter de blev titreret til deres fulde behandlingsdosis i uge 2.
English: Photosensitivity reaction*
Danish: Lysfølsomhed*
English: What you need to know before you take Dafiro HCT
Danish: Det skal du vide, før du begynder at tage Dafiro HCT
English: In patients with mild to moderate hepatic impairment without cholestasis, the maximum recommended dose is 80 mg valsartan and therefore Dafiro HCT is not suitable in this group of patients (see sections 4.3, 4.4 and 5.2).
Danish: Den maksimale anbefalede dosis til patienter med let til moderat nedsat leverfunktion uden kolestase er 80 mg valsartan, og Dafiro HCT er derfor ikke egnet til denne patientgruppe (se pkt.
English: Dafiro HCT should be used only after correction of any pre-existing sodium and/or volume depletion.
Danish: Dafiro HCT bør kun bruges efter korrektion af eventuel eksisterende væske- eller natriummangel.
English: When switching eligible elderly hypertensive patients (see section 4.1) to Dafiro HCT, the lowest available dose of the amlodipine component should be used.
Danish: 4.1) med nedsat leverfunktion skiftes til Dafiro HCT, skal den laveste tilgængelige amlodipinkombination anvendes.
English: If you stop taking Dafiro HCT
Danish: Hvis du holder op med at tage Dafiro HCT
English: In marmosets at comparable doses, the changes were similar though more severe, particularly in the kidney where the changes developed to a nephropathy including raised blood urea nitrogen and creatinine.
Danish: Hos silkeaber, som fik sammenlignelige doser, sås tilsvarende, men mere alvorlige ændringer, især i nyrerne, hvor der udvikledes nefropati, omfattende forhøjet carbamid g kreatinin.
English: If you forget to take Dafiro HCT
Danish: Hvis du har glemt at tage Dafiro HCT
English: Multipack: 280 (20 packs of 14) film-coated tablets.
Danish: Multipakning: 280 (20 pakninger med 14) filmovertrukne tabletter.
English: Based on available data from epidemiological studies, cumulative dose-dependent association between hydrochlorothiazide and NMSC has been observed.
Danish: Tilgængelige data fra epidemiologiske studier viser en kumulativ dosis-afhængig forbindelse mellem hydrochlorthiazid og non-melanom hudkræft.
English: if you have gout (uric acid crystals in the joints).
Danish: - hvis du har urinsyregigt (urinsyrekrystaller i leddene).
English: Concomitant use of Dafiro HCT with aliskiren-containing products in patients with diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m2) (see sections 4.5 and 5.1).
Danish: - Samtidig brug af Dafiro HCT og lægemidler indeholdende aliskiren er kontraindiceret hos patienter med diabetes mellitus eller nedsat nyrefunktion (GFR < 60 ml/min/1,73 m 2) (se pkt.
English: What Dafiro HCT contains
Danish: Dafiro HCT indeholder: