FrancophonIA/ELRC3.0 huggingface dataset:
English: The syringe inside the pen is a 1 mL pre-filled syringe made of glass (Type I) with a bromobutyl rubber stopper and thermoplastic and polypropylene rigid needle shield, containing 0.5 mL of solution.
Slovenian: 6.5 Vrsta ovojnine in vsebina 1-ml napolnjena injekcijska brizga iz stekla (tip I) z zamaškom iz bromobutilne gume in termoplastičnim in polipropilenskim togim pokrovom za iglo, ki vsebuje 0,5 ml raztopine.
English: Supplies needed for your Plegridy Pen injection:
Slovenian: Pripomočki, ki jih potrebujete za injiciranje zdravila Plegridy v injekcijskem peresniku:
English: Do not rest the pen on the injection site until you are ready to inject.
Slovenian: Opozorilo: Injekcijskega peresnika ne položite na mesto za injiciranje, dokler niste pripravljeni na injiciranje.
English: Each inner carton contains 2 pens in a protective plastic tray.
Slovenian: 2 injekcijska peresnika na zatesnjenem plastičnem pladnju.
English: For example, if you are prescribed other medicines, or if you have a blood test. Plegridy may affect the other medicines or the test result.
Slovenian: Zdravilo Plegridy lahko vpliva na druga zdravila ali na rezultate preiskav.
English: The Plegridy Initiation Pack contains 1x 63 micrograms pre-filled syringe (orange labelled syringe, 1st dose) and 1x 94 micrograms pre-filled syringe (blue labelled syringe, 2nd dose) in sealed plastic trays.
Slovenian: Začetno pakiranje zdravila Plegridy vsebuje 1 x 63-mikrogramsko napolnjeno injekcijsko brizgo (brizga z oranžno nalepko, 1. odmerek) in 1 x 94-mikrogramsko napolnjeno injekcijsko brizgo (brizga z modro nalepko, 2. odmerek) na zatesnjenih plastičnih pladnjih.
English: Step 4: Choose and clean your injection site a. Choose an injection site in your thigh, abdomen, or the back of your upper arm (see highlighted areas in Figure D).
Slovenian: a. Izberite mesto injiciranja na stegnu, trebuhu ali hrbtni strani nadlahti (glejte označena območja na sliki D).
English: Plegridy also significantly reduced the risk of relapse by 39% (p=0.0003), the risk of sustained disability progression confirmed at 12 weeks by 38% (p=0.0383) and at 24 weeks (post-hoc analysis) by 54% (p=0.0069), the number of new or newly enlarging T2 lesions by 67% (p<0.0001), the number of Gd-enhancing lesions by 86% (p<0.0001) and the number of new T1 hypointense lesions compared to placebo by 53% (p<0.0001).
Slovenian: Plegridy je tudi značilno zmanjšalo tveganje za recidiv za 39 % (p = 0,0003), tveganje za trajno napredovanje bolezni, potrjeno pri 12. tednih za 38 % (p = 0,0383) in pri 24. tednih (analiza post-hoc) za
English: Plegridy 63 micrograms solution for injection in pre-filled syringe Plegridy 94 micrograms solution for injection in pre-filled syringe Plegridy 125 micrograms solution for injection in pre-filled syringe Plegridy 63 micrograms solution for injection in pre-filled pen Plegridy 94 micrograms solution for injection in pre-filled pen Plegridy 125 micrograms solution for injection in pre-filled pen
Slovenian: Plegridy 63 mikrogramov raztopina za injiciranje v napolnjeni injekcijski brizgi Plegridy 94 mikrogramov raztopina za injiciranje v napolnjeni injekcijski brizgi Plegridy 125 mikrogramov raztopina za injiciranje v napolnjeni injekcijski brizgi Plegridy 63 mikrogramov raztopina za injiciranje v napolnjenem injekcijskem peresniku Plegridy 94 mikrogramov raztopina za injiciranje v napolnjenem injekcijskem peresniku Plegridy 125 mikrogramov raztopina za injiciranje v napolnjenem injekcijskem peresniku
English: Repeated dose toxicology studies were limited to 5 weeks as exposure was greatly diminished from 3 weeks onwards, due to the formation of anti-drug antibodies by rhesus monkeys to human interferon beta-1a.
Slovenian: 3 tednu močno zmanjšala, ker so se pri opicah Rhesus razvila protitelesa proti zdravilu na človeški interferon beta-1a.
English: Plegridy pre-filled syringe must not be used if the liquid is coloured, cloudy, or contains floating particles.
Slovenian: Zdravilo Plegridy napolnjena injekcijska brizga se ne sme uporabiti, če je tekočina obarvana, motna ali če vsebuje plavajoče delce.
English: External heat sources such as hot water must not be used to warm Plegridy.
Slovenian: Za ogrevanje zdravila Plegridy ni dovoljeno uporabljati zunanjih virov toplote, na primer vroče vode.
English: 1 pre-filled syringe of 63 micrograms 1 pre-filled syringe of 94 micrograms
Slovenian: 1 napolnjena injekcijska brizga s 63 mikrogrami 1 napolnjena injekcijska brizga s 94 mikrogrami
English: Do not touch, clean, or manipulate the needle cover.
Slovenian: Opozorilo: Varovala igle se ne dotikajte, ne čistite ga in ne posegajte vanj.
English: Sometimes you will need to remind other healthcare professionals that you are being treated with Plegridy.
Slovenian: Včasih bo treba zdravstvene delavce opomniti, da se zdravite z zdravilom Plegridy, na primer, če vam želijo predpisati druga zdravila ali če pri vas opravljajo krvne preiskave.
English: Instructions for injecting Plegridy pre-filled syringe
Slovenian: Navodila za injiciranje zdravila Plegridy napolnjena injekcijska brizga
English: Patients with relapsing-remitting MS have periods when the disease is not active (remission) in between flare-ups of symptoms (relapses).
Slovenian: To prekine sporočila, ki potekajo med možgani in drugimi deli telesa, in povzroča simptome MS. Bolniki z recidivno-remitentno MS imajo med zagoni simptomov (recidivi) obdobja, ko bolezen ni aktivna (remisija).
English: Which dose
Slovenian: Kolikšen odmerek
English: Box of two 125 microgram pre-filled pens (grey labelled pens) in a protective plastic tray.
Slovenian: Škatla z dvema 125-mikrogramskima napolnjenima injekcijskima peresnikoma (peresnika s sivima nalepkama) na zatesnjenem plastičnem pladnju.
English: Precautions to be taken before handling or administering the medicinal product Once removed from the refrigerator, Plegridy should be allowed to warm to room temperature (up to 25°C) for about 30 minutes prior to injection.
Slovenian: Zdravilo Plegridy naj se po odstranitvi iz hladilnika in pred injiciranjem ogreje na sobno temperaturo (do 25 °C) v približno 30 minutah.
English: Cases of TMA, manifested as thrombotic thrombocytopenic purpura (TTP) or haemolytic uraemic syndrome (HUS), including fatal cases, have been reported with interferon beta products.
Slovenian: Trombotična mikroangiopatija (TMA) (učinki skupine) Pri uporabi zdravil z interferonom beta so poročali o primerih TMA, ki se kažejo kot trombotična trombocitopenična purpura (TTP) ali hemolitični uremični sindrom (HUS), vključno s smrtnimi primeri.
English: Hypothyroidism and hyperthyroidism have been observed with the use of interferon beta products.
Slovenian: Pri uporabi zdravil z interferonom beta so opazili hipotiroidizem in hipertiroidizem.
English: Do not use more than one pen per 14-day period (every 2 weeks).
Slovenian: Ne uporabite več kot enega peresnika v 14-dnevnem obdobju (vsaka 2 tedna).
English: Plegridy 125 mcg injection peginterferon beta-1a SC
Slovenian: Plegridy 125 µg injekcija peginterferon beta-1a s.c.
English: Re-capping could cause the pen to lock.
Slovenian: Pri ponovnem natikanju pokrova bi se namreč lahko zbodli.
English: Solution for injection Initiation Pack
Slovenian: raztopina za injiciranje začetno pakiranje
English: Caution should be used when administering Plegridy to patients with severe renal impairment.
Slovenian: Pri dajanju zdravila Plegridy bolnikom s hudo ledvično okvaro je potrebna previdnost.
English: The efficacy and safety of Plegridy was assessed from the placebo-controlled first year of a 2 year randomised, double-blind, clinical study in patients with relapsing remitting multiple sclerosis (the ADVANCE study).
Slovenian: Učinkovitost in varnost zdravila Plegridy so ocenili v prvem letu 2-letne, s placebom kontrolirane,
English: - Throw away any syringe that is kept out of the fridge for more than 30 days.
Slovenian: - Vsak peresnik, shranjen zunaj hladilnika več kot 30 dni, zavrzite.
English: Do not touch or blow this area again before giving the injection.
Slovenian: Tega mesta se do injiciranja ne dotikajte več in nanj ne pihajte.
English: • Adhesive bandage
Slovenian: • Napolnjeno injekcijsko brizgo zdravila
English: Plegridy 125 micrograms every 2 weeks
Slovenian: Placebo Zdravilo Plegridy 125 mikrogramov vsaka 2 tedna
English: - The 125 micrograms grey syringes are provided in a pack containing either two or six pre-filled syringes.
Slovenian: - Pakiranje s sivimi injekcijskimi brizgami s 125 mikrogrami vsebuje dve ali šest napolnjenih injekcijskih brizg.
English: Mean white blood cell counts remained within normal limits in patients treated with Plegridy.
Slovenian: zdravljenih z zdravilom Plegridy, ostalo znotraj normalnih meja.
English: Do not reuse the Plegridy pre-filled syringe.
Slovenian: Napolnjene injekcijske brizge zdravila Plegridy ne uporabite ponovno.
English: Step 6: Give the injection a. Hold the pen over your injection site.
Slovenian: a. Injekcijski peresnik držite nad mestom za injiciranje.
English: Do not pull back on the plunger.
Slovenian: Ne vlecite bata nazaj.
English: Urinary (renal) clearance is postulated to be a major excretory pathway for Plegridy.
Slovenian: Domneva se, da je glavna pot izločanja zdravila Plegridy urinski (ledvični) očistek.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING MULTIPACK OUTER CARTON Pre-filled pen 125 mcg Multipack (with bluebox)
Slovenian: SKUPNO PAKIRANJE ZUNANJA ŠKATLA Napolnjen injekcijski peresnik 125 µg skupno pakiranje (z »modrim okencem«)
English: b. Firmly press and hold down the pen on your injection site.
Slovenian: b. Trdno pritisnite injekcijski peresnik na mesto injiciranja in ga držite pri miru.
English: No information is available on the potential effects of peginterferon beta-1a on male fertility.
Slovenian: Informacij o možnih učinkih peginterferona beta-1a na plodnost pri moških ni na voljo.
English: Instructions for injecting Plegridy pre-filled syringe BEFORE YOU START How to inject Plegridy
Slovenian: Navodila za injiciranje zdravila Plegridy napolnjena injekcijska brizga Kako injicirati zdravilo Plegridy
English: Quickly insert the needle straight into the skin fold until the needle is fully under the skin.
Slovenian: Iglo vstavite naravnost v kožno gubo s hitrim gibom, tako da igla v celoti zdrsne v kožo (glejte sliko H).
English: Do not reuse your Plegridy pen.
Slovenian: Injekcijskega peresnika zdravila Plegridy ne uporabite ponovno.
English: Dosage schedule
Slovenian: Režim odmerjanja
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Pre-Filled Syringe Label Initiation Pack
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Začetno pakiranje napolnjene injekcijske brizge, nalepka
English: • After the needle is in, let go of your skin.
Slovenian: • Po vstavitvi igle kožno gubo izpustite.
English: (See Figure H).
Slovenian: (navedeno v poglavju 6).
English: Annualised relapse rate Rate ratio
Slovenian: Letni delež recidiva
English: Respiratory, thoracic and mediastinal disorders
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora pljučna arterijska hipertenzija┼ neznana
English: • Plegridy pre-filled syringe is for injecting the medicine under the skin only (subcutaneous)
Slovenian: • Napolnjena injekcijska brizga zdravila Plegridy je namenjena izključno injiciranju zdravila pod kožo
English: Very rare (<1/10,000) Not known (cannot be estimated from the available data)
Slovenian: neznana (ni mogoče oceniti iz razpoložljivih podatkov) Organski sistem po MedDRA Neželeni učinek
English: Sodium acetate trihydrate Acetic acid, glacial Arginine hydrochloride Polysorbate 20
Slovenian: FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi natrijev acetat trihidrat koncentrirana ocetna kislina argininijev klorid polisorbat 20 voda za injekcije
English: Do not use more than one pre-filled syringe per 14-day period (every 2 weeks).
Slovenian: Ne uporabite več kot ene napolnjene injekcijske brizge v 14-dnevnem obdobju (vsaka 2 tedna).
English: • Close the pack and put pack back in the fridge after removing one pre-filled syringe.
Slovenian: • Ko ste iz pakiranja vzeli eno napolnjeno injekcijsko brizgo, zaprite pakiranje in ga vrnite v hladilnik.
English: Musculoskeletal and connective tissue disorders
Slovenian: Bolezni mišično-skeletnega sistema in vezivnega tkiva mialgija zelo pogosti artralgija
English: - If you have trouble handling the syringe, ask your doctor or nurse who may be able to help.
Slovenian: - Če imate težave z uporabo brizge, prosite za pomoč zdravnika ali medicinsko sestro.
English: After your injection Step 9: Disposing of the used Plegridy pre-filled syringe
Slovenian: 9. korak: Zavrzite uporabljeno napolnjeno injekcijsko brizgo zdravila Plegridy.
English: The active substance in Plegridy is peginterferon beta-1a.
Slovenian: Kaj je zdravilo Plegridy Učinkovina v zdravilu Plegridy je peginterferon beta-1a.
English: Starting Plegridy
Slovenian: Plegridy.
English: When you are ready to inject, carefully follow the instructions in section 7 “Instructions for injecting Plegridy pre-filled pen”, at the end of this leaflet.
Slovenian: Preden začnete uporabljati zdravilo Plegridy, preberite navodila v poglavju 7 »Navodila za injiciranje zdravila Plegridy napolnjeni injekcijski peresnik« na koncu tega navodila.
English: This may cause the pen to accidently lock.
Slovenian: To bi namreč lahko povzročilo nehoten zaklep injekcijskega peresnika.
English: Plegridy 63 mcg injection Plegridy 94 mcg injection peginterferon beta-1a SC
Slovenian: Plegridy 63 µg injekcija Plegridy 94 µg injekcija peginterferon beta-1a s.c.
English: Race had no effect on the pharmacokinetics of peginterferon beta-1a in a population pharmacokinetic analysis.
Slovenian: Populacijska farmakokinetična analiza ni pokazala učinkov rase na farmakokinetiko peginterferona beta-1a.
English: • Plegridy pre-filled syringe should be injected into the abdomen, thigh, or the back of the upper arm. (See Figure E).
Slovenian: • Napolnjeno injekcijsko brizgo zdravila Plegridy je treba injicirati v trebuh, stegno ali zadnji del nadlahti.
English: When you are ready to inject, carefully follow the instructions in section 7 “Instructions for injecting Plegridy pre-filled syringe”, at the end of this leaflet.
Slovenian: Preden začnete uporabljati zdravilo Plegridy, preberite navodila v poglavju 7 »Navodila za injiciranje zdravila Plegridy napolnjena injekcijska brizga« na koncu tega navodila.
English: Serum concentration of peginterferon beta-1a was dose-proportional in the range of 63 to 188 micrograms as observed in a single dose and a multiple dose study in healthy subjects.
Slovenian: Koncentracija peginterferona beta-1a v serumu je bila sorazmerna z odmerkom in v razponu od 63 do
English: How to store Plegridy
Slovenian: Shranjevanje zdravila Plegridy
English: Decreased peripheral blood counts in all cell lines, including rare pancytopenia and severe thrombocytopenia, have been reported in patients receiving interferon beta.
Slovenian: Pri bolnikih, ki so prejemali interferon beta, so poročali o zmanjšanju perifernih krvnih vrednosti vseh celičnih vrst, vključno z redko pancitopenijo in hudo trombocitopenijo.
English: First injection: 63 micrograms, choose orange pen
Slovenian: Prva injekcija: 63 mikrogramov, izberite oranžno brizgo dan 14 (94 mikrogramov)
English: Warnings and precautions Talk to your doctor if you have ever had:
Slovenian: Opozorila in previdnostni ukrepi Posvetujte se z zdravnikom, če ste kadar koli imeli: - depresijo ali težave, ki vplivajo na vaše razpoloženje, - misli o tem, da bi naredili samomor,
English: Close the pack and put back in the fridge after removing one pen.
Slovenian: Ko ste iz pakiranja vzeli en injekcijski peresnik, zaprite pakiranje in ga vrnite v hladilnik.
English: Step 10: Care for your injection site
Slovenian: 10. korak: Negujte mesto injiciranja.
English: Treatment with Plegridy should not be restarted (see section
Slovenian: Zdravljenja z zdravilom Plegridy se ne sme ponovno uvesti (glejte poglavje 4.8).
English: Of a total of 1468 patients, 658 patients continued at least 4 years of treatment with Plegridy.
Slovenian: Plegridy z neprekinjenim zdravljenjem do 4 leta, kot kažejo klinična merila in merila MRS za aktivnost bolezni MS. Od vsega skupaj 1.468 bolnikov je 658 bolnikov nadaljevalo zdravljenje z zdravilom Plegridy vsaj 4 leta.
English: België/Belgique/Belgien
Slovenian: België/Belgique/Belgien Biogen Belgium NV/SA
English: 1 pre-filled pen of 63 micrograms 1 pre-filled pen of 94 micrograms
Slovenian: 1 napolnjen injekcijski peresnik s 63 mikrogrami 1 napolnjen injekcijski peresnik s 94 mikrogrami
English: If you get some or all of these symptoms: - Increased bruising or bleeding - Extreme weakness - Headache, dizziness or light-headedness
Slovenian: - pogostejše modrice ali krvavitve, - izjemna šibkost, - glavobol, omotica ali vrtoglavica,
English: Alopecia$
Slovenian: Bolezni kože in podkožja alopecija$
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Pre-Filled Pen Label Initiation pack
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Začetno pakiranje napolnjenega injekcijskega peresnika, nalepka
English: Step 9: Dispose of used Plegridy pen
Slovenian: 9. korak: Zavrzite uporabljeni injekcijski peresnik zdravila Plegridy.
English: Less than 1% of Plegridy treated patients experienced a serious hypersensitivity event (e.g. angioedema, urticaria) and they recovered promptly after treatment with anti-histamines and/or corticosteroids.
Slovenian: zdravljenih z zdravilom Plegridy, se je pojavil resen preobčutljivostni dogodek (npr. angioedem, urtikarija),
English: Pack sizes: - The Plegridy Initiation Pack contains one orange pre-filled syringe of 63 micrograms and one blue pre-filled syringe of 94 micrograms.
Slovenian: - Začetno pakiranje zdravila Plegridy vsebuje eno oranžno napolnjeno injekcijsko brizgo s 63 mikrogrami in eno modro napolnjeno injekcijsko brizgo s 94 mikrogrami.
English: No gender effect on the pharmacokinetics of peginterferon beta-1a was found in a population pharmacokinetic analysis.
Slovenian: Populacijska farmakokinetična analiza ni pokazala učinkov spola na farmakokinetiko peginterferona beta-1a.
English: Preparing for your injection Step 1: Remove your pen from the fridge.
Slovenian: 1. korak: Vzemite injekcijski peresnik iz hladilnika.
English: • If needed, apply a gauze pad or adhesive bandage or plaster to the injection site.
Slovenian: • Po potrebi mesto injiciranja prekrijte z blazinico iz gaze ali obližem.
English: Do not use the Plegridy pre-filled syringe if the liquid is coloured, cloudy, or has floating particles in it. o You might see air bubbles in the Plegridy medicine.
Slovenian: Ne uporabite napolnjene injekcijske brizge zdravila Plegridy, če je tekočina obarvana, motna ali so v njej prisotni delci.
English: What Plegridy is used for
Slovenian: Za kaj uporabljamo zdravilo Plegridy
English: Injection Site
Slovenian: Mesto injiciranja
English: In post marketing experience, serious hypersensitivity events including cases of anaphylaxis (frequency not known) have been reported following Plegridy administration.
Slovenian: V obdobju trženja zdravila so po dajanju zdravila Plegridy poročali o resnih preobčutljivostnih dogodkih, vključno s primeri anafilaksije
English: Plegridy 125 micrograms solution for injection in pre-filled syringe peginterferon beta-1a
Slovenian: Plegridy 125 mikrogramov raztopina za injiciranje v napolnjenem injekcijskem peresniku peginterferon beta-1a
English: - If you have trouble handling the pen, ask your doctor or nurse who may be able to help.
Slovenian: - Če imate težave z uporabo peresnika, prosite za pomoč zdravnika ali medicinsko sestro.
English: Initiation Pack.
Slovenian: - Navodilo shranite.
English: Hypersensitivity Anaphylaxis1
Slovenian: Bolezni imunskega sistema angioedem občasni preobčutljivost anafilaksija1
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Pre-Filled Syringe Label 125 mcg
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Napolnjen injekcijski peresnik 125 µg, nalepka
English: Solution for injection 2 pre-filled pens.
Slovenian: raztopina za injiciranje 2 napolnjena injekcijska peresnika.
English: Proportion of subjects relapsed HR
Slovenian: Delež oseb z recidivom
English: No information is available on the effects of peginterferon beta-1a on male fertility in animals.
Slovenian: Informacij o učinkih peginterferona beta-1a na plodnost pri samcih živali ni na voljo.
English: Solution for injection 2 pre-filled pens
Slovenian: raztopina za injiciranje 2 napolnjena injekcijska peresnika
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS Pre-Filled Syringe Double Lid Initiation Pack
Slovenian: PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA PRETISNEM OMOTU ALI DVOJNEM TRAKU
English: Plegridy 125 micrograms solution for injection in pre-filled syringe Each pre-filled syringe contains 125 micrograms of peginterferon beta-1a* in 0.5 mL solution for injection.
Slovenian: Plegridy 125 mikrogramov raztopina za injiciranje v napolnjeni injekcijski brizgi Ena napolnjena injekcijska brizga vsebuje 125 mikrogramov peginterferona beta-1a* v 0,5 ml raztopine za injiciranje.
English: Injection site reactions, including injection site necrosis, have been reported with the use of subcutaneous interferon beta.
Slovenian: Pri uporabi subkutanega interferona beta so poročali o reakcijah na mestu injiciranja, vključno z nekrozo na mestu injiciranja.
English: Do not share your Plegridy pen.
Slovenian: Injekcijskega peresnika zdravila Plegridy ne delite z drugimi.
English: c. Let your injection site dry on its own before injecting your dose.
Slovenian: c. Pred injiciranjem odmerka počakajte, da se mesto za injiciranje samo posuši.
English: Day 28 and then every two weeks after that (125 micrograms)
Slovenian: 125 mikrogramov (za dan 28 in nato vsaka dva tedna).
English: Pre-Filled Pen 125 mcg Multipack (without bluebox)
Slovenian: SKUPNO PAKIRANJE NOTRANJA ŠKATLA Napolnjen injekcijski peresnik 125 µg skupno pakiranje (brez »modrega okenca«)
English: Day 14
Slovenian: 2. odmerek 14. dan modra
English: In the ATTAIN extension study, long-term efficacy with Plegridy was maintained with continuous treatment up to 4 years as shown by clinical and MRI measures of MS disease activity.
Slovenian: V podaljšani študiji ATTAIN so vzdrževali dolgoročno učinkovitost z zdravilom
English: Peginterferon beta-1a has not been tested for reproductive toxicity in pregnant animals.
Slovenian: Vpliv na sposobnost razmnoževanja Peginterferon beta-1a ni bil testiran glede vpliva na sposobnost razmnoževanja pri brejih živalih.
English: HR: Hazard ratio
Slovenian: RT: razmerje tveganja IZ: interval zaupanja
English: Step 7: Remove the Plegridy pen from your injection site a. After the clicking sound has stopped, lift the pen from your injection site.
Slovenian: 7. korak: Injekcijski peresnik zdravila Plegridy odstranite z mesta injiciranja.
English: Preparing for your injection Step 1: Remove your pre-filled syringe from the fridge
Slovenian: 1. korak: Vzemite napolnjeno injekcijsko brizgo iz hladilnika.
English: How to use Plegridy
Slovenian: Kako deluje zdravilo Plegridy
English: - Irritation at an injection site, which can lead to skin and tissue damage (injection site necrosis).
Slovenian: Težave se lahko med uporabo zdravila Plegridy poslabšajo: - resne težave z jetri ali ledvicami; - draženje na mestu injiciranja, ki lahko povzroči poškodovanje kože in tkiva (nekroza na mestu injiciranja).
English: Do not share your Plegridy pre-filled syringe.
Slovenian: Napolnjene injekcijske brizge zdravila Plegridy ne delite z drugimi.
English: (uncommon - may affect up to 1 in 100 people) If you get any of these: - Difficulty breathing - Swelling around the face (lips, tongue or throat) - Skin rashes or redness
Slovenian: (pojavijo se lahko pri največ 1 od 10 bolnikov) - siljenje na bruhanje (navzea) ali bruhanje, - izpadanje las (alopecija),