FrancophonIA/ELRC3.0 huggingface dataset:
English: The cardiovascular profile of modafinil is of particular concern in the OSA population given the already elevated baseline risk.
Estonian: Modafiniili kardiovaskulaarsed tüsistused tekitavad erilist ettevaatlikkust obstruktiivse uneapnoe populatsioonis, kus baasrisk on juba suurem.
English: • Vertigo (spinning sensation).
Estonian: • vertiigo (pööritustunne);
English: • Flushing.
Estonian: • migreen;
English: • Abnormal periods.
Estonian: • tavatud menstruatsioonitsüklid;
English: Rare cases of serious or life-threatening rash, including Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), and Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) have been reported in adults and children in worldwide post-marketing experience.
Estonian: Üleilmsel turustamisjärgsel kasutamisel on täiskasvanutel ja lastel teatatud raskekujulisest või eluohtlikust lööbest, sh Stevens-Johnsoni sündroomist (SJS), toksilisest epidermaalsest nekrolüüsist ning ravimilööbest koos eosinofiilia ja süsteemsete sümptomitega (DRESS).
English: • Loss of appetite, feeling sick, stomach pain, indigestion, diarrhoea or constipation
Estonian: • isupuudus, haiglane enesetunne, maovalu, seedimishäired, kõhulahtisus või kõhukinnisus;
English: • Back pain, neck pain, muscle pain, muscle weakness, leg cramps, joint pain, twitching or tremor.
Estonian: • seljavalu, kaelavalu, lihasvalu, lihasnõrkus, krambid jalgades, liigesevalu, lihastõmblused või värisemine;
English: • Omeprazole (for acid reflux, indigestion or ulcers).
Estonian: • Omeprasool (happerefluksi, seedimishäirete või haavandite korral).
English: Serious nervous system and psychiatric related events such as suicidal ideation, psychotic episodes, and depression have also been identified in association to modafinil.
Estonian: Modafiniili kasutamisega on seostatud ka raskeid närvisüsteemi ja psühhiaatriahäireid, nagu suitsiidimõtteid, psühhoosiepisoode ja depressiooni.
English: Cardiovascular effects
Estonian: Kardiovaskulaarsed nähud
English: Uncommon: sweating, rash, acne, pruritis
Estonian: Aeg-ajalt: higistamine, lööve, akne, sügelus.
English: • Weakness.
Estonian: • suukuivus;
English: BEFORE YOU TAKE MODAFINIL CONTAINING MEDICINAL PRODUCTS
Estonian: KUIDAS MODAFINIILI SISALDAVAID RAVIMEID VÕTTA
English: Common: abdominal pain, nausea, dry mouth, diarrhoea, dyspepsia, constipation Uncommon: flatulence, reflux, vomiting, dysphagia, glossitis, mouth ulcers
Estonian: Aeg-ajalt: puhitus, refluks, oksendamine, düsfaagia, glossiit, suuhaavandid.
English: Musculoskeletal and connective tissue disorders Uncommon: back pain, neck pain, myalgia, myasthenia, leg cramps, arthralgia, twitch
Estonian: Lihas-skeleti ja sidekoe kahjustused Aeg-ajalt: seljavalu, kaelavalu, müalgia, müasteenia, krambid jalgades, artralgia, kontraktsioon.
English: Take special care with Modafinil containing medicinal products if you
Estonian: Eriline ettevaatus on vajalik modafiniili sisaldavate ravimitega:
English: • Dry mouth.
Estonian: Manustamisviis Suukaudne.
English: Common: blurred vision Uncommon: abnormal vision, dry eye
Estonian: Aeg-ajalt: ebanormaalne nägemine, silmade kuivus.
English: Statistically significant differences were seen in the subjective parameters (ESS and CGI-C).
Estonian: Subjektiivsete näitajate (Epworthi unisuse skaala (Epworth Sleepiness Scale) ja üldkliiniliste muutuste skaala (Clinical Global Impression of Change)) osas täheldati statistiliselt olulisi erinevusi.
English: Infections and infestations Uncommon: pharyngitis, sinusitis
Estonian: Infektsioonid ja infestatsioonid Aeg-ajalt: farüngiit, sinusiit.
English: Modafinil "Teva" 100 mg tablets
Estonian: Modafinil "Teva" 100 mg
English: MARKETING AUTHORISATION NUMBER(S) [To be completed nationally]
Estonian: MÜÜGILOA NUMBER (NUMBRID)
English: 100 MG tablets
Estonian: 100 mg tablett
English: MODIODAL 100 mg tablets
Estonian: MODIODAL 100 mg/tablett
English: ANNEX II
Estonian: LISA III
English: Skin and hypersensitivity reactions
Estonian: Naha- ja ülitundlikkusreaktsioonid
English: • Chest pain
Estonian: • peapööritus;
English: MODIODAL 100MG/TA B
Estonian: MODIODAL 100 mg
English: General disorders and administration site conditions Common: asthenia, chest pain Uncommon: peripheral oedema, thirst
Estonian: Üldised häired ja manustamiskoha reaktsioonid Sage: asteenia, valu rindkeres.
English: 1 CCID50: Cell Culture Infective Dose 50 %
Estonian: 1 CCID50: rakukultuure 50% ulatuses nakatav annus
English: What is Balaxur?
Estonian: Mis on Balaxur?
English: It was expected to be available as tablets (20 mg/10 mg).
Estonian: Seda kavatseti turustada tablettidena (20 mg/10 mg).
English: In addition, the company pooled and analysed the results from the different studies together.
Estonian: Lisaks koondas ettevõte eri uuringute tulemused ja analüüsis neid.
English: The company that applied for authorisation is Merz Pharmaceuticals GmbH, Germany.
Estonian: Müügiluba taotles Merz Pharmaceuticals GmbH (Saksamaa).
English: Therefore, the CHMP was of the opinion that the benefits of Balaxur did not outweigh its risks and recommended that it be refused marketing authorisation.
Estonian: Komitee oli seetõttu arvamusel, et Balaxuri kasulikkus ei ole suurem kui kaasnevad riskid, ja soovitas müügiloa andmisest keelduda.
English: The company informed the CHMP that there are no patients currently included in clinical trials with Balaxur in the European Union.
Estonian: Ettevõte teatas inimravimite komiteele, et praegu Balaxuri kliinilistes uuringutes Euroopas patsiente ei osale.
English: Balaxur is a medicine that contains two active substances, memantine hydrochloride and donepezil hydrochloride.
Estonian: Balaxur on ravim, mis sisaldab kaht toimeainet: memantiinvesinikkloriidi ja donepesiilvesinikkloriidi.
English: Balaxur was expected to be used to treat moderate to moderately severe Alzheimer's disease, in patients who are already taking a daily dose of 20 mg memantine and 10 mg donepezil.
Estonian: Balaxurit kavatseti kasutada mõõduka kuni mõõdukalt raske Alzheimeri tõve ravimiseks patsientidel, kes juba võtavad ööpäevas 20 mg memantiini ja 10 mg donepesiili.
English: The company also presented information intended to show the use of memantine and donepezil in combination to treat Alzheimer's disease across the European Union, including the available guidelines for treating Alzheimer's disease in different European countries.
Estonian: Ettevõte eitas ka teabe memantiini ja donepesiili koos kasutamise kohta Alzheimeri tõve ravis Euroopa Liidus, sealhulgas Alzheimeri tõve olemasolevate ravisuuniste kohta Euroopa riikides.
English: Balaxur is a combination treatment containing two active substances which are already authorised in the EU to treat the symptoms of Alzheimer's disease.
Estonian: Balaxur on kombinatsioonravim, mille mõlemal toimeainel juba on Euroopa Liidus müügiluba ja mis on näidustatud Alzheimeri tõve sümptomite raviks.
English: How is Balaxur expected to work?
Estonian: Milline on Balaxuri eeldatav toime?
English: The Committee also noted that a published study did not show a significant improvement in patients taking the combination treatment when compared with memantine alone.
Estonian: Komitee märkas ka, et ühes avaldatud uuringus puudus kombinatsiooniravimit võtnud patsientide seisundi oluline paranemine ainult memantiini võtnud patsientide seisundiga võrreldes.
English: Memantine works by blocking types of receptor called NMDA receptors, to which the neurotransmitter glutamate normally attaches.
Estonian: Memantiini toime seisneb selles, et see blokeerib teatud retseptoreid (NMDA-retseptoreid), millele tavaliselt kinnitub neurotransmitter glutamaat.
English: What consequences does this refusal have for patients in clinical trials?
Estonian: Kuidas mõjutab müügiloa andmisest keeldumine praegu kliinilistes uuringutes osalevaid patsiente?
English: The effects of Balaxur were first tested in experimental models before being studied in humans.
Estonian: Enne inimuuringuid kontrolliti Balaxuri toimet muude katsetega.
English: What was Balaxur expected to be used for?
Estonian: Milleks kavatseti Balaxurit kasutada?
English: On 18 October 2012, the Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion, recommending the refusal of the marketing authorisation for the medicinal product Balaxur, intended for the treatment of moderate to moderately severe Alzheimer's disease in patients who are already taking memantine and donepezil.
Estonian: 18. oktoobril 2012 võttis inimravimite komitee vastu negatiivse arvamuse, soovitades keelduda Balaxuri müügiloa andmisest.
English: By blocking NMDA receptors, memantine helps to reduce the symptoms of Alzheimer's disease.
Estonian: NMDA-retseptoreid blokeerides aitab memantiin
English: Especially severe cases may require more prolonged and more frequent treatment.
Estonian: Eriti rasked juhtumid vajavad pikemat ja sagedasemat ravi.
English: Do not eat, drink or smoke during application.
Estonian: Mitte süüa, juua ega suitsetada preparaadi manustamise ajal.
English: Date of first authorisation: 02/04/2003.
Estonian: Esmase müügiloa väljastamise kuupäev 02/04/2003.
English: This is not a sign of intoxication and disappears within some minutes without treatment.
Estonian: See ei ole mürgistuse tunnuseks ning kaob mõne minuti jooksul ilma ravita.
English: It is a parasiticide which is active against many internal and external parasites.
Estonian: See on parasititsiid, mis toimib paljudesse sise- ja välisparasiitidesse.
English: Do not use on canaries.
Estonian: Mitte kasutada kanaarilindudel.
English: Imidacloprid is toxic for birds, especially canaries.
Estonian: Imidaklopriid on toksiline lindudele, eriti kanaarilindudele.
English: Container material
Estonian: Konteineri materjal
English: Each unit dose (pipette) contains:
Estonian: Iga doos (pipett) sisaldab:
English: Seek the advice of your veterinarian.
Estonian: Pea nõu oma loomaarstiga.
English: ATCvet code: QP54AB52.
Estonian: ATCvet kood: QP54AB52
English: Do not allow recently treated animals to groom each other.
Estonian: Mitte lasta ravitud loomadel üksteist lakkuda.
English: The T ½ in dogs is about 28.4 days.
Estonian: T 1/2 koertel on ligikaudu 28,4 päeva.
English: Do not use in kittens under 9 weeks of age.
Estonian: Mitte kasutada kassipoegadele vanuses alla 9 nädala.
English: In the study these reactions were common (seen in 2 of 106 treated dogs).
Estonian: Katsetes täheldati neid reaktsioone sagedasti (2 koeral 106-st ravitud koerast).
English: The mean T ½ in cats ranges between 18.7 and 25.7 days.
Estonian: Keskmine T½ kassidel on vahemikus 18,7 ja 25,7 päeva.
English: In these severe cases concomitant supportive treatment is necessary as treatment with the product alone may not be sufficient to prevent death of the animal.
Estonian: Selliste raskete juhtumite korral on vajalik kaasnev toetav ravi, kuna ravi vaid selle preparaadiga ei pruugi olla piisav looma surma vältimiseks.
English: Do not exceed the recommended dose.
Estonian: Mitte ületada soovituslikke doose.
English: Do not use in dogs classified as Class 4 for heartworm disease as the safety of the product has not been evaluated in this animal group.
Estonian: Mitte kasutada südameussile positiivsetel koertel klassifikatsiooniga 4. klass kuna selle preparaadi ohutust ei ole sellises loomade grupis hinnatud.
English: The product's efficacy has not been tested in ferrets weighing over 2 kg and therefore the duration of effect might be shorter in these animals.
Estonian: Preparaadi efektiivsust ei ole testitud tuhkrutel kehakaaluga üle 2 kg ning seetõttu võib toime pikkus olla neil lühem.
English: Dogs should not be allowed to swim in surface waters for 4 days after treatment.
Estonian: Koertel ei tohiks lubada ujuda veekogudes 4 päeva jooksul pärast ravi.
English: Chemically, it is more accurately described as a chloronicotinyl nitroguanidine.
Estonian: Keemiliselt kirjeldatakse seda kui kloornikotinüül nitroguanidiidi.
English: Therefore, the use of this product should be based on the assessment of each individual case and on local epidemiological information about the current susceptibility of the target species in order to limit the possibility of a future selection for resistance.
Estonian: Seepärast peab selle preparaadi kasutamine põhinema iga juhtumi individuaalsel hinnangul ja kohalikul epidemioloogilisel informatsioonil sihtliigi tundlikkuse kohta limiteerimaks resistentsuse tekke võimalust.
English: In certain individual cats Notoedres cati infestation may be severe.
Estonian: Individuaalselt võib teatud kassidel Notoedres cati nakkus olla raske.
English: Date of last renewal: 14/01/2013.
Estonian: Müügiloa viimase uuendamise kuupäev 14/01/2013.
English: Following absorption from the skin, moxidectin is distributed systemically throughout the body tissues but due to its lipophilicity it is concentrated mainly in the fat.
Estonian: Pärast nahalt imendumist jaotub moksidektiin süsteemselt kõikjal keha kudedes, kuid oma lipofiilsuse tõttu kontsentreerub peamiselt rasvas.
English: Do not use in puppies under 7 weeks of age.
Estonian: Mitte kasutada koerakutsikatele vanuses alla 7 nädala.
English: 1 pipette 2 pipettes 3 pipettes 4 pipettes 6 pipettes 9 pipettes 12 pipettes 21 pipettes 42 pipettes
Estonian: 1 pipett 2 pipetti 3 pipetti 4 pipetti 6 pipetti 9 pipetti 12 pipetti 21 pipetti 42 pipetti
English: A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.
Estonian: 30 päeva pärast ravi on soovitav loomade veterinaarne läbivaatus, kuna mõned loomad võivad vajada teistkordset ravi.
English: For external use only.
Estonian: Ainult välispidiseks manustamiseks.
English: Efficacy against adult Dirofilaria repens has not been tested under field conditions.
Estonian: Preparaadi efektiivsust täiskasvanud Dirofilaria repens' i vastu ei ole välitingimustes testitud.
English: Dosage schedule for cats:
Estonian: Doseerimisskeem kassidele:
English: For ferrets: Do not use Advocate for dogs.
Estonian: Tuhkrutele: mitte kasutada Advocate'i koertele.
English: The result is flaccid paralysis of affected parasites, followed by their death and/or expulsion.
Estonian: Tulemuseks on parasiidi lõtv paralüüs, millele järgneb surm ja/või väljutamine.
English: Therefore they can be treated without special precautions.
Estonian: Seetõttu võib neid ravida ilma ettevaatusabinõusid tarvitamata.
English: These signs disappear without further treatment.
Estonian: Need tunnused kaovad ilma ravita.
English: A field study has shown that in heartworm positive dogs with microfilaraemia there is a risk of severe respiratory signs (coughing, tachypnea and dyspnea) that may require prompt veterinary treatment.
Estonian: Katsed on näidanud, et südameusssidele positiivsetel koertel, kellel on mikrofilareemia, on risk tõsisteks respiratoorseteks tunnusteks (köhimine, tahhüpnoe ja düspnoe), mis võivad vajada kohest veterinaarset ravi.
English: The product tastes bitter.
Estonian: Preparaat on kibeda maitsega.
English: Moxidectin, 23-(O-methyloxime)-F28249 alpha is a second-generation macrocyclic lactone of the milbemycin family.
Estonian: Moksidektiin, 23-(O-metüüloksiim)-F28249 alfa, on milbemütsiini perekonda kuuluv teise põlvkonna makrotsükliline laktoon.
English: Transient mydriasis, salivation, vomiting and transient rapid respiration were observed.
Estonian: Täheldati mööduvat müdriaasi, salivatsiooni, oksendust ja mööduvat kiiret hingamist.
English: Microfilaria
Estonian: Mikrofilaaria
English: No interactions between Advocate and routinely used veterinary medicinal products or medical or surgical procedures have been observed.
Estonian: Koostoimed Advocate'i ja tavakasutuses olevate veterinaarravimite ja meditsiiniliste või kirurgiliste protseduuride vahel puuduvad.
English: The ensuing inhibition of cholinergic transmission in insects results in paralysis and death.
Estonian: Kolinergilise ülekande inhibeerumine putukatel viib paralüüsi ja surmani.
English: Avoid contact with skin, eyes or mouth.
Estonian: Vältida kontakti naha, silmade ja suuga.
English: If adult heartworm infection is diagnosed, the infection should be treated in accordance with current scientific knowledge.
Estonian: Kui on diagnoositud nakkus täiskasvanud südameussidega, tuleb haigust ravida vastavalt kasutuselolevatele teaduslikele ravimeetoditele.
English: The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes.
Estonian: Preparaati võib manustada ka aastaringselt või siis vähemalt 1 kuu enne esimest oodatavat kokkupuudet sääskedega.
English: Allow the application site to dry before permitting contact with such materials.
Estonian: Lasta manustamiskohal enne nende materjalidega kokkupuutumist kuivada.
English: Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Estonian: Müügipakendis veterinaarpreparaadi kõlblikkusaeg: 3 aastat.
English: In all cases it is essential that the treatment should be continued until skin scrapings are negative on at least 2 consecutive monthly occasions.
Estonian: Võimalusel tuleb ravi jätkata kuni nahakaabete analüüsid on negatiivsed vähemalt kahel kuul järjest.
English: Under heavy flea pressure it may be necessary to repeat administration after 2 weeks.
Estonian: Tugeva kirburünnaku korral võib vajalikuks osutuda kordusravi tegemine 2 nädala pärast.
English: The safety of the product has only been evaluated in dogs classified as either Class 1 or 2 for heartworm disease in laboratory studies and in a few Class 3 dogs in a field study.
Estonian: Selle preparaadi ohutust on hinnatud südameussi osas klassifikatsiooniga 1. ja 2.klassi koertel laborkatsetes ja mõnedel 3. klassi koertel välikatsetes.
English: The drug has a persistent action and protects dogs for 4 weeks after a single application against reinfection with the following parasites: Dirofilaria immitis, Dirofilaria repens, Angiostrongylus vasorum.
Estonian: Ravim omab püsivat toimet ja kaitseb koeri 4 nädalat pärast ühekordset manustamist taasnakatumise eest järgmiste parasiitidega: Dirofilaria immitis, Dirofilaria repens, Angiostrongylus vasorum.
English: When 40 % of the unit dose was given orally, severe neurological signs were observed.
Estonian: Kui 40% doosist anti suukaudselt, täheldati raskeid neuroloogilisi häireid.
English: See sections 4.5 and 6.6.
Estonian: Keskkonnaomadused vt lõike 4.5. ja 6.6.
English: Wash hands thoroughly after use.
Estonian: Pärast preparaadi käsitsemist pesta käed.
English: Moxidectin interacts with GABA and glutamate-gated chloride channels.
Estonian: Moksidektiin mõjutab GABA ja glutamaat-sõltuvaid kloori kanaleid.
English: The product has a persistent action and protects cats for 4 weeks after a single application against reinfection with Dirofilaria immitis.
Estonian: Ravim omab püsivat toimet ja kaitseb kassi 4 nädalat pärast ühekordset manustamist taasnakatumise eest Dirofilaria immitis`ega.
English: The treatment schedule should be based on individual veterinary diagnosis and on the local epidemiological situation.
Estonian: Raviskeem peab põhinema individuaalsel veterinaarsel diagnoosil ja kohalikul epidemioloogilisel olukorral.
English: The administration of a single dose every 4 weeks for 2 to 4 months is efficacious against Demodex canis and leads to a marked improvement of clinical signs particularly in mild to moderate cases.
Estonian: Manustades ühe doosi 2-4 korda 4-nädalaste vahedega toimib efektiivselt Demodex canis`esse ning kliinilised tunnused vähenevad märkimisväärselt, eriti just kergetel ja mõõdukatel juhtudel.
English: Imidacloprid, 1-(6-Chloro-3-pyridylmethyl)-N-nitro-imidazolidin-2-ylideneamine is an ectoparasiticide belonging to the chloronicotinyl group of compounds.
Estonian: Imidaklopriid, 1-(6-kloor-3-püridüülmetüül)-N-nitro-imidasolidiin-2-ülideneamiin, on ektoparasititsiid, mis kuulub kloornikotinüülide gruppi.
English: Therefore the use in dogs with obvious or severe symptoms of the disease should be based on a careful benefit-risk assessment by the treating veterinarian.
Estonian: Seepärast peab selle haiguse ilmsete või raskete sümptomitega koertel kasutamine põhinema raviva loomaarsti poolt antud hoolikal kasu-riski hinnangul.
English: It is advisable to prevent auto-coprophagia between the two treatments in order to prevent possible reinfection.
Estonian: Võimaliku taasnakatumise ärahoidmiseks on soovitatav kahe ravi vahepeal vältida autokoprofaagiat.
English: Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Estonian: Parasiitidel võib kujuneda resistentsus ükskõik millise anthelmintikumide klassi suhtes, sellesse klassi kuuluvate preparaatide korduval järjestikusel manustamisel.
English: The use of the product should be based on the confirmed diagnosis of mixed infection (or risk of infection, where prevention applies) at the same time (see also sections 4 and 8).
Estonian: Selle preparaadi kasutamine peab põhinema samal ajal segainfektsiooni kinnitatud diagnoosil (või siis infektsiooni riskil profülaktikaks) (vt ka osa 4 ja 8).
English: Gastrointestinal signs (vomiting, diarrhoea, inappetence) and lethargy are also common adverse reactions following treatment in such dogs.
Estonian: Seedekulgla tunnused (oksendamine, diarröa, isutus) ja letargia on samuti sagedased kõrvaltoimed selliste koerte ravimisel.
English: Do not apply an excessive amount of solution at any one spot, as that could cause some of the product to run down the animal's side.
Estonian: Mitte manustada ühte kohta liiga palju, sest sel juhul võib preparaat mööda looma külgi maha voolata.
English: Treatment should be stopped in dogs that show no improvement or do not respond in mite count after 2 months treatment.
Estonian: Koertel tuleb ravi peatada kui ei ole nähtavat paranemist või lestade koguse vähenemist proovides peale kahekuulist ravi.
English: 0.4 ml, 1.0 ml, 2.5 ml and 4.0 ml per pipette.
Estonian: 0,4 ml, 1,0 ml, 2,5 ml ja 4,0 ml pipetis.
English: When the product is applied in 3 to 4 separate spots, specific care should be taken to prevent the animal licking the application sites.
Estonian: Kui preparaati manustatakse 3-4 erinevasse kohta tuleb jälgida, et loom ei lakuks manustamiskohti.
English: The use of activated charcoal may be beneficial.
Estonian: Kasulikuks võib osutuda aktiivsöe manustamine.
English: The treatment schedule should be based on the local epidemiological situation.
Estonian: Raviskeem peab põhinema kohalikul epidemioloogilisel olukorral.
English: Capillaria) boehmi (adults) The product should be administered monthly for two consecutive months.
Estonian: Capillaria) boehmi (täiskasvanud) tõrje Seda preparaati tuleb manustada kord kuus kahel järjestikusel kuul.
English: The entire contents of the pipette should be applied evenly as 3 or 4 spots along the top of the back, from between the shoulders to the base of the tail.
Estonian: Kogu pipeti sisu manustada ühtlaselt 3-4 kohta selja keskjoonele (abaluude vahelt kuni sabajuureni).
English: The safety of Advocate has not been evaluated when administered on the same day as an adulticide.
Estonian: Advocate' i ohutust ei ole hinnatud kasutades seda samal päeval täiskasvanud vormide vastase ravimiga.
English: ANNEX III LABELLING AND PACKAGE LEAFLET
Estonian: III LISA PAKENDI MÄRGISTUS JA PAKENDI INFOELHT
English: It is slowly eliminated from the plasma as manifested by detectable moxidectin concentrations in plasma throughout the treatment interval of one month.
Estonian: Väljutatakse plasmast aeglaselt nagu ilmnes tuvastatavate moksidektiinide kontsentratsioonide alusel raviprotseduuride vahele jääva kuu aja vältel.
English: Ivermectin-sensitive Collie dogs tolerated up to 5 times the recommended dose repeated at monthly intervals without any adverse effects, but the safety of application at weekly intervals has not been investigated in ivermectin-sensitive Collie dogs.
Estonian: Ivermektiinile tundlikud kollid talusid soovituslikust doosist 5 korda suuremaid, igakuiselt manustatud doose ilma kõrvaltoimeteta, kuid ohutust ei ole uuritud iganädalasel manustamisel ivermektiinile tundlikel kollidel.