FrancophonIA/ELRC3.0 huggingface dataset:
English: The method of administration is 200 mg of mifepristone in a single oral dose, followed 36 to 48 hours later by the administration of the prostaglandin analogue gemeprost 1 mg per vaginam.
Slovenian: Način uporabe je 200 mg mifepristona v enkratnem peroralnem odmerku, kateremu po 36 do 48 urah sledi vaginalna uporaba 1 mg prostaglandinskega analoga gemeprosta.
English: The method of administration is 200 mg of mifepristone (1 tablet) should be taken, followed 36 to 48 hours later by the administration of a prostaglandin analogue ( 1 pessary containing 1 mg of gemeprost placed in the vagina).
Slovenian: Način uporabe je 200 mg mifepristona (1 tableta), čemur po 36 do 48 urah sledi uporaba prostaglandinskega analoga (1 vaginalne globule, ki vsebuje 1 mg gemeprosta in se vstavi v nožnico).
English: Amendments to be included in the relevant sections of the summary of product characteristic
Slovenian: Spremembe, ki jih je treba vključiti v zadevna poglavja povzetka glavnih značilnosti zdravila
English: The valid package leaflet is the final version achieved during the Coordination group procedure with the following amendments (highlighted below in bold underlined) in section 3:
Slovenian: Veljavno navodilo za uporabo je končna različica, ki je bila sestaviljena med postopkom koordinacijske skupine in ki vključuje naslednje spremembe (spodaj označene z okrepljenim in podčrtanim besedilom) v poglavju 3:
English: Summary of product characteristics and package leaflet
Slovenian: Povzetek glavnih značilnosti zdravila in navodilo za uporabo
English: Mifepristone Linepharma is for oral use.
Slovenian: Zdravilo Mifepristone Linepharma je namenjeno peroralni uporabi.
English: The valid summary of product characteristics is the final version achieved during the Coordination group procedure with the following amendments (highlighted below in bold underlined) in the section
Slovenian: Veljavni povzetek glavnih značilnosti zdravila je končna različica, ki je bila sestaviljena med postopkom koordinacijske skupine in ki vključuje naslednje spremembe (spodaj označene z okrepljenim in podčrtanim besedilom) v poglavju 4.2:
English: Amendments to be included in the relevant sections of the package leaflet
Slovenian: Spremembe, ki jih je treba vključiti v zadevna poglavja navodila za uporabo
English: HOW TO USE MIFEPRISTONE LINEPHARMA Always take Mifepristone Linepharma exactly as your doctor has told you.
Slovenian: Pri uporabi zdravila Mifepristone Linepharma natančno upoštevajte navodila svojega zdravnika.
English: It is available as capsules (20 mg).
Slovenian: Na voljo je v obliki kapsul (20 mg).
English: The main measure of effectiveness was based on an assessment of the patients' nerve damage and quality of life after 18 months of treatment.
Slovenian: Glavno merilo učinkovitosti je temeljilo na oceni poškodbe živcev pri bolniku in kakovosti življenja po 18 mesecih zdravljenja.
English: The European Commission granted a marketing authorisation valid throughout the European Union for Vyndaqel on 16 November 2011.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Vyndaqel, veljavno po vsej Evropski uniji, izdala 16. novembra 2011.
English: This is a summary of the European public assessment report (EPAR) for Vyndaqel.
Slovenian: To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Vyndaqel.
English: The material will include a leaflet containing information on the risks of the medicine including the risks to the unborn baby and on how to contribute to a post-marketing study and a surveillance programme for pregnant women.
Slovenian: To bo vključevalo brošuro z informacijami o tveganjih zdravila, vključno s tveganji za nerojenega otroka, in napotke o tem, kako prispevati k študiji zdravila iz obdobja po pridobitvi dovoljenja za promet in programu nadzora nosečnic.
English: The results did not include patients with more severe disease who left the study early because they needed to undergo a liver transplant.
Slovenian: Rezultati ne vključujejo bolnikov s hujšo obliko bolezni, ki so iz študije izstopili predčasno, ker so potrebovali presaditev jeter.
English: The medicine presented no major safety concerns and the risks were considered to be manageable.
Slovenian: Zdravilo ni pokazalo nobenih večjih varnostnih zadržkov, tveganja, povezana z njim, pa so obvladljiva.
English: What measures are being taken to ensure the safe and effective use of Vyndaqel?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Vyndaqel?
English: In 45% of patients taking Vyndaqel, nerve function either improved or stabilised, compared with 30% of patients taking placebo.
Slovenian: Pri 45 % bolnikov, ki so jemali zdravilo Vyndaqel, se je delovanje živcev bodisi izboljšalo bodisi stabiliziralo, v primerjavi s 30 % bolnikov, ki so prejemali placebo.
English: The company will also provide long-term post-marketing safety data.
Slovenian: Zagotovila bo tudi dolgoročne podatke o varnosti zdravila v obdobju po pridobitvi dovoljenja za promet.
English: This means that because transthyretin amyloidosis is rare, for scientific reasons, it has not been possible to obtain complete information about Vyndaqel.
Slovenian: To pomeni, da zaradi redkosti transtiretinske amiloidoze iz znanstvenih razlogov ni bilo mogoče pridobiti popolnih informacij o njem.
English: Treatment should be started and supervised by a doctor knowledgeable in the management of patients with this disease.
Slovenian: Zdravljenje lahko uvede in nadzoruje le zdravnik, ki ima izkušnje z zdravljenjem bolnikov s to boleznijo.
English: The company that makes Vyndaqel will carry out a study on the effects of the medicine in a subgroup of patients with certain genetic mutations.
Slovenian: Družba, ki izdeluje zdravilo Vyndaqel, bo izvedla študijo učinkov zdravila v podskupini bolnikov z določenimi genskimi mutacijami.
English: For more information about treatment with Vyndaqel, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Slovenian: Za več informacij o zdravljenju z zdravilom Vyndaqel preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Vyndaqel have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo upoštevati zdravstveni delavci in bolniki za varno in učinkovito uporabo tega zdravila so prav tako vključeni v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: Vyndaqel has been authorised under ‘exceptional circumstances'.
Slovenian: Zdravilo Vyndaqel je pridobilo dovoljenje za promet „v izjemnih okoliščinah“.
English: The summary of the opinion of the Committee for Orphan Medicinal Products for Vyndaqel can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/Rare disease designations.
Slovenian: Povzetek mnenja Odbora za zdravila sirote o zdravilu Vyndaqel je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/Rare disease designations.
English: It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Vyndaqel.
Slovenian: Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil to zdravilo, na podlagi česar je oblikoval mnenje za izdajo dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
English: The most common side effects with Vyndaqel (seen in more than 1 patient in 10) are urinary tract infection (infection of the structures that carry urine), vaginal infection, upper abdominal pain (stomach ache) and diarrhoea.
Slovenian: Najpogostejši neželeni učinki zdravila Vyndaqel (opaženi pri več kot 1 bolniku od 10) so vnetje sečil (okužba struktur za odvajanje seča), vnetje nožnice, bolečine v zgornjem delu trebuha (bolečine v želodcu) in driska.
English: The CHMP therefore concluded that the benefits of Vyndaqel are greater than its risks and recommended that it be granted marketing authorisation.
Slovenian: CHMP je zaključil, da so koristi zdravila Vyndaqel večje od z njim povezanih tveganj, in priporočil, da se zanj izda dovoljenje za promet.
English: The full EPAR for Vyndaqel can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Slovenian: Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Vyndaqel je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
English: In patients with transthyretin amyloidosis, a blood protein called transthyretin is defective and breaks easily.
Slovenian: Pri bolnikih s transtiretinsko amiloidozo je krvna beljakovina, imenovana transtiretin, poškodovana in hitro razpade.
English: The broken protein forms a fibrous substance called amyloid that is deposited in tissues and organs around the body, including around nerves, where it interferes with their normal functions.
Slovenian: Razgrajena beljakovina tvori vlaknasto snov, imenovano amiloid, ki se odlaga v tkivih in organih po vsem telesu, vključno okoli živcev, kjer moti njihovo normalno delovanje.
English: Vyndaqel is used in adult patients with the early stage of nerve disease (stage 1).
Slovenian: Uporablja se pri odraslih bolnikih z zgodnjo stopnjo živčnega obolenja (stopnja 1).
English: The company that markets Vyndaqel will provide educational material to all doctors expected to prescribe Vyndaqel.
Slovenian: Družba, ki trži zdravilo Vyndaqel, bo vsem zdravnikom, ki naj bi ga predpisovali, priskrbela ustrezno izobraževalno gradivo.
English: For the full list of all side effects and restrictions with Vyndaqel, see the package leaflet.
Slovenian: Za celoten seznam vseh neželenih učinkov in omejitev pri uporabi zdravila Vyndaqel glejte navodilo za uporabo.
English: Because the number of patients with transthyretin amyloidosis is low, the disease is considered ‘rare', and Vyndaqel was designated an ‘orphan medicine' (a medicine used in rare diseases) on 28 August
Slovenian: Ker je bolnikov s transtiretinsko amiloidozo malo, velja ta bolezen za redko, zato je bilo zdravilo Vyndaqel 28. avgusta 2006 določeno kot „zdravilo sirota“ (zdravilo za zdravljenje redkih bolezni).
English: What benefit has Vyndaqel shown during the studies?
Slovenian: Kakšne koristi je zdravilo Vyndaqel izkazalo med študijami?
English: Vyndaqel is a medicine that contains the active substance tafamidis.
Slovenian: Vyndaqel je zdravilo, ki vsebuje zdravilno učinkovino tafamidis.
English: Other information about Vyndaqel
Slovenian: Druge informacije o zdravilu Vyndaqel
English: It attaches to transthyretin, which prevents the protein from breaking up, thereby stopping the formation of amyloid and slowing down the progression of the nerve disease.
Slovenian: Z vezavo na transtiretin prepreči njegovo razgradnjo, s čemer se ustavi tvorba amiloida in upočasni napredovanje obolenja živcev.
English: The active substance in Vyndaqel, tafamidis, is a transthyretin stabilizer.
Slovenian: Zdravilna učinkovina zdravila Vyndaqel, tafamidis, je stabilizator transtiretina.
English: Vyndaqel is used to delay nerve damage caused by transthyretin amyloidosis, a hereditary disease in which fibres called amyloid build up in tissues around the body including around the nerves.
Slovenian: Zdravilo Vyndaqel se uporablja za upočasnitev napredovanja poškodbe živcev, ki jo povzroča transtiretinska amiloidoza, tj. dedna bolezen, pri kateri se amiloidna vlakna kopičijo v tkivih po telesu, vključno okoli živcev.
English: Vyndaqel was more effective than placebo at treating patients with transthyretin amyloidosis.
Slovenian: Zdravilo Vyndaqel je bilo učinkovitejše od placeba pri zdravljenju bolnikov s transtiretinsko amiloidozo.
English: Vyndaqel was compared with placebo (a dummy treatment) in 128 patients with transthyretin amyloidosis.
Slovenian: Zdravilo Vyndaqel so primerjali s placebom (zdravilom brez zdravilne učinkovine) pri 128 bolnikih s transtiretinsko amiloidozo.
English: What is the risk associated with Vyndaqel?
Slovenian: Kakšna tveganja so povezana z zdravilom Vyndaqel?
English: What information is still awaited for Vyndaqel?
Slovenian: Katere informacije o zdravilu Vyndaqel še pričakujemo?
English: Why has Vyndaqel been approved?
Slovenian: Zakaj je bilo zdravilo Vyndaqel odobreno?
English: The CHMP noted that, apart from in patients who left the study because they needed a liver transplant, Vyndaqel was more effective than placebo in delaying nerve damage in patients with transthyretin amyloidosis.
Slovenian: Odbor za zdravila za uporabo v humani medicini (CHMP) je menil, da se je zdravilo Vyndaqel pri bolnikih s transtiretinsko amiloidozo razen bolnikov, ki so študijo predčasno zapustili, ker so potrebovali presaditev jeter, izkazalo za učinkovitejše od placeba pri upočasnitvi napredovanja poškodbe živcev.
English: How is Vyndaqel used?
Slovenian: Kako se zdravilo Vyndaqel uporablja?
English: How has Vyndaqel been studied?
Slovenian: Kako je bilo zdravilo Vyndaqel raziskano?
English: How does Vyndaqel work?
Slovenian: Kako zdravilo Vyndaqel deluje?
English: What is Vyndaqel?
Slovenian: Kaj je zdravilo Vyndaqel?
English: EU/1/09/537/001 Mozobil
Slovenian: EU/1/09/537/001
English: 20 mg/ml Solution for injection
Slovenian: 20 mg/ml raztopina za injiciranje subkutana uporaba viala (steklo)
English: Pack size
Slovenian: Mozobil
English: 2 As lower confidence limit (p = 0.95)
Slovenian: 2 Kot spodnja meja zaupanja (p = 0,95)
English: _*_One 2-ml dose contains: rotavirus serotype* G1
Slovenian: _*_ En 2-ml odmerek vsebuje: G1 serotip* rotavirusa
English: not less than 2.3 x 106 IU1, 2 * human-bovine rotavirus reassortants (live), produced in Vero cells.
Slovenian: P1[8] serotip* rotavirusa ne manj kot 2,3 x 106 IE1, 2 * prerazporejeni humano-bovini rotavirusi (živi), pridobljeni na celicah Vero 1 Infektivnih enot
English: Invented name Strength Pharmaceutical Form
Slovenian: Številka EU Izmišljeno ime Jakost Farnacevtska oblika Pot uporabe
English: Content
Slovenian: Ovojnina Vsebina
English: Regulation 1530/02 / OJL230 of 28 August 2002
Slovenian: Uredba 1530/02 / OJL230 z dne 28. avgusta 2002
English: Gonazon for fish:
Slovenian: Gonazon za ribe:
English: No antidotes are available.
Slovenian: Protistrupov ni na voljo.
English: Fish should be anaesthetised.
Slovenian: Ribe je treba anestezirati.
English: Withdraw the needle from the skin.
Slovenian: Izvlecite iglo iz kože.
English: Do not store above 25C.
Slovenian: Ne shranjujte pri temperaturi nad 25 C.
English: Position the bitch on her back.
Slovenian: Psico namestimo na hrbet.
English: The recommended dose is 32 µg/kg body weight.
Slovenian: Priporočeni odmerek je 32 µg/kg telesne mase.
English: Benzyl alcohol (1%)
Slovenian: Benzilni alkohol (1 %)
English: The transition between the stimulatory and inhibitory effects is completed within approximately one month.
Slovenian: Prehod od stimulativnega do zaviralnega delovanja se zaključi približno v enem mesecu.
English: It is recommended to strip fish after injection at intervals of approximately 50-100 degree days.
Slovenian: Ribe je po injekciji priporočljivo smukati v presledkih po približno 50-100 dnevnih stopinj.
English: In some cases this can be related to the use of the compound too early in the spawning season.
Slovenian: To je včasih lahko posledica prezgodnje uporabe spojine v sezoni mrestenja.
English: Additional sterile vials will be supplied on request.
Slovenian: Dodatne sterilne viale so na voljo po naročilu.
English: This brief phase may result in induced heat within one to four weeks following the first administration of the implant (see section 4.5).
Slovenian: Posledica te kratke faze je lahko indukcija gonitve v enem do štirih tednih po prvi uporabi implantata (glejte poglavje 4.5).
English: Gonazon for dogs: Intervet GesmbH Siemensstrasse 107 A-1210 Wien Austria
Slovenian: Gonazon za pse: Intervet GesmbH Siemensstrasse 107 A-1210 Wien Avstrija
English: REMOVAL:
Slovenian: ODSTRANITEV:
English: Do not use in bitches (prepubertal and adult) intended for breeding (see section 4.7).
Slovenian: Ne uporabite pri psicah (pred puberteto in odraslih), namenjenih za vzrejo (glejte poglavje 4.7).
English: The risk of inducing a fertile heat is low in metoestrus (5%).
Slovenian: Tveganje, da bi spodbudili fertilni estrus, je v metestrusu majhno (5 %).
English: The duration of prevention of gonadal function is obtained as detailed in the table below:
Slovenian: Trajanje preprečevanja gonadne funkcije je navedeno v spodnji tabeli:
English: 3 - 6 years old
Slovenian: 3 -6 let trajanje blokade
English: An overdose will not accelerate the onset or increase the degree of ovulation.
Slovenian: Prevelik odmerek ne pospeši začetka ovulacije ali poveča njene stopnje.
English: For Arctic charr, injections should be given only if the water temperature is < 8°C.
Slovenian: Jezerskim zlatovčicam smemo injekcije dajati samo pri temperaturi vode < 8 ºC.
English: Simultaneous administration of five implants during a oneyear period was well tolerated.
Slovenian: Prenašanje sočasne uporabe petih implantatov v obdobju enega leta je bilo dobro.
English: THE WORDS “FOR ANIMAL TREATMENT ONLY” AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE, if applicable
Slovenian: BESEDILO “SAMO ZA ŽIVALI” IN POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE, če je navedba smiselna
English: There are no data available for animals treated on more than two occasions.
Slovenian: Ni na voljo podatkov o živalih, pri katerih bi izdelek uporabili več kot dvakrat.
English: The recommended dose is one implant per bitch.
Slovenian: Priporočeni odmerek je en implantat za eno psico.
English: Inability to locate and remove Gonazon will not have serious effects on the general health of the dog.
Slovenian: Če Gonazona ne najdemo in odstranimo, nima resnejših učinkov na splošno zdravje psice.
English: Water for injection
Slovenian: voda za injekcije
English: Instruct the owner to keep the administration site clean and dry for 24 hours.
Slovenian: Lastnika poučite, da mora biti mesto dajanja čisto in suho 24 ur.
English: Ensure that the administration site is clean and dry.
Slovenian: Poskrbite, da bo mesto dajanja čisto in suho.
English: If the implant cannot be palpated in the month following administration, the owner is encouraged to seek veterinary advice as efficacy cannot be ensured in these cases.
Slovenian: Če ga lastnik v mesecu po vnosu ne more otipati, naj se posvetuje z veterinarjem, ker v tem primeru učinkovitost ni zagotovljena.
English: Make a stab incision, approximately 5 mm long, along the elevated near end of the implant.
Slovenian: Napravimo vbodni rez, približno 5 mm, vzdolž dvignjenega bližnjega konca implantata.
English: Keep out of the reach and sight of children.
Slovenian: Zdravilo shranjujte izven dosega in pogleda otrok.
English: Sterile container: 50-ml empty
Slovenian: Sterilni vsebnik: po 50 ml, prazen
English: Operators should wash their hands after use of the product.
Slovenian: Osebe, ki uporabljajo izdelek, si morajo po uporabi umiti roke.
English: A large proportion (68%) of the first heat after a single treatment in adult bitches were non-ovulatory.
Slovenian: Pri velikem deležu (68 %) prve gonitve po enkratni uporabi pri odraslih psicah ni prišlo do ovulacije.
English: At the end of a one year treatment, it may not be possible to locate and remove the implant in approximately 10% of cases.
Slovenian: Po enem letu v približno 10 % primerov ne moremo določiti mesta implantata in ga odstraniti.
English: GnRH analogues are peptides.
Slovenian: Analogi GnRH so peptidi.
English: The product is contraindicated in bitches intended for breeding (adult and prepubertal) as laboratory studies in which dogs received 3 simultaneous implants for a period of 12 months revealed a reduction in the numbers of live pups at whelping and weaning compared to an untreated control group.
Slovenian: Zdravilo je kontraindicirano pri psicah, namenjenih za vzrejo (odraslih in pred puberteto), ker je bilo v laboratorijskih študijah, v katerih so psi sočasno prejeli 3 implantate v obdobju 12 mesecev, število živih mladičev ob kotitvi in odstavitvi manjše kot v nezdravljeni kontrolni skupini.
English: Therefore, if heat is observed, contact with male dogs should be prevented until all signs of heat (vulvar swelling, bleeding and attractiveness to male dogs) cease.
Slovenian: Če se pojavi gonitev, moramo zato preprečiti stik s samci, dokler vsi znaki gonitve (nabreklo zunanje spolovilo, krvavitev in privlačnost za samce) ne minejo.
English: Do not mix with other medicinal products.
Slovenian: Ne mešajte z drugimi zdravili.
English: Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (EMEA) http://www.emea.europa.eu/.
Slovenian: Podrobne informacije o tem zdravilu za uporabo v veterinarski medicini so na voljo na spletni strani Evropske agencije za zdravila (European Medicines Agency, EMEA) http://www.emea.europa.eu/.
English: Grasp it with forceps and remove.
Slovenian: Primemo ga s pinceto in odstranimo.
English: Azagly-nafarelin
Slovenian: Azagli-nafarelin
English: In the absence of clinical information, do not treat bitches less than 3 kg bodyweight and bitches of giant breeds over 45 kg bodyweight.
Slovenian: Ker ni na voljo kliničnih podatkov, ne uporabite pri psicah z manjšo telesno maso od 3 kg in pri zelo velikih pasmah s telesno maso nad 45 kg.
English: Preferred injection volume per kg fish (depending on fish
Slovenian: Primeren injekcijski volumen na kg rib (glede na velikost
English: The product should not be used in fish maintained in water temperatures that would normally inhibit ovulation as this can result in a decrease in egg quality.
Slovenian: Izdelka ne smemo uporabljati pri ribah, ki jih gojimo v vodi s temperaturo, katera bi normalno zavirala ovulacijo, ker se lahko zmanjša kakovost iker.
English: Administration of Gonazon at other stages of the cycle may induce heat that may be fertile.
Slovenian: Uporaba Gonazona v drugih obdobjih cikla lahko spodbudi gonitev, ki je fertilna.
English: The method of administration is as follows:
Slovenian: Dajemo ga po naslednji metodi:
English: Intraperitoneal (IP) use
Slovenian: Intraperitonealna (i.p.)
English: Separate empty sterile containers
Slovenian: Prazni, sterilni vsebniki
English: Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (EMEA) http://www.emea.europa.eu
Slovenian: Podrobne informacije o tem zdravilu za uporabo v veterinarski medicini so na voljo na spletni strani Evropske agencije za zdravila (European Medicines Agency, EMEA) http://www.emea.europa.eu
English: Risk of overdose is negligible owing to the type of formulation and administration (single dose implant for subcutaneous administration).
Slovenian: Tveganje prevelikega odmerka je neznatno zaradi oblike pripravka in načina dajanja (enoodmerni implantat za podkožno dajanje).
English: Inject intraperitoneally along the central line, 1/2 to 1 fin length in front of the pelvic fin base.
Slovenian: Injiciramo intraperitonealno vzdolž osrednje linije, 1/2 do 1 dolžino plavuti pred osnovo pelvične plavuti.
English: To minimise this problem, caution needs to be exercised to ensure that the implant is administered by subcutaneous injection, particularly in dogs with pronounced depots of subcutaneous fat.
Slovenian: Da bi to težavo kolikor je možno zmanjšali, moramo poskrbeti, da se implantat vnese s podkožno injekcijo, zlasti pri psicah z izrazitim podkožnim maščevjem.
English: The implant may be administered to bitches from the age of four months.
Slovenian: Implantat lahko uporabimo pri psicah od starosti štirih mesecev.
English: As a consequence, there is no follicular follicle growth (hence no oestrus is observed) and no ovulation.
Slovenian: Posledica tega je, da preneha folikularna rast (zato se estrus ne pojavi) in ne pride do ovulacije.