FrancophonIA/ELRC3.0 huggingface dataset:
English: Norvir should be started at 250 mg/m² and increased at 2 to 3 day intervals by 50 mg/m² twice daily (please refer to the Norvir 100 mg powder for oral suspension Summary of Product Characteristics).
Croatian: Liječenje treba početi dozom lijeka Norvir od 250 mg/m2 dvaput na dan i povećavati je u razmacima od 2 do 3 dana za po 50 mg/m2 (vidjeti Sažetak opisa svojstava lijeka za Norvir 100 mg prašak za oralnu suspenziju).
English: The signs of toxicity observed in animals (mice and rats) included decreased activity, ataxia, dyspnoea and tremors.
Croatian: Među znakove toksičnosti zamijećene u životinja (miševi i štakori) ubrajaju se smanjena aktivnost,
English: Norvir should be started at 250 mg/m² and increased at 2 to 3 day intervals by 50 mg/m² twice daily.
Croatian: Liječenje treba početi dozom lijeka Norvir od 250 mg/m2 dvaput na dan i povećavati je u razmacima od 2 do 3 dana za po 50 mg/m2.
English: Clorazepate, diazepam, estazolam, flurazepam, oral and parenteral midazolam
Croatian: Klorazepat, diazepam, estazolam, flurazepam, oralni i parenteralni midazolam
English: Step 7.
Croatian: Korak 7.
English: If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Croatian: valja razmotriti prekid ili obustavu liječenja.
English: 16 q24h
Croatian: 16 svakih 24h
English: b. Place the syringe tip into the liquid.
Croatian: Stavite štrcaljku u tekućinu.
English: 1, single dose
Croatian: 1, jednokratna doza
English: 5, single dose
Croatian: 5, jednokratna doza
English: Concomitant use of sildenafil for the treatment of erectile dysfunction with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer should be with caution and in no instance should sildenafil doses exceed 25 mg in 48 hours (see also section 4.4).
Croatian: Pri primjeni sildenafila za liječenje erektilne disfunkcije istodobno s ritonavirom doziranim kao antiretrovirusnim lijekom ili kao farmakokinetičkim pojačivačem nužan je oprez, a sildenafil se ni u kojem slučaju ne smije davati u dozama većima od 25 mg u 48 sati (vidjeti i dio 4.4).
English: - Atorvastatin or rosuvastatin (for high cholesterol) as Norvir may raise the blood levels of these medicines.
Croatian: Atorvastatin ili rosuvastatin (za visok kolesterol), jer Norvir može povisiti razine tih lijekova u krvi.
English: How do I take the correct dose of Norvir powder for oral suspension mixed with liquid?
Croatian: Norvir praška za oralnu suspenziju pomiješanog s tekućinom?
English: The interaction profiles of HIV-protease inhibitors, co-administered with low dose ritonavir, are dependant on the specific co-administered protease inhibitor.
Croatian: Profil interakcija inhibitora HIV-proteaza, kada se daju istodobno s ritonavirom u malim dozama, ovisi o određenom inhibitoru proteaza koji se daje.
English: ↑ 49-fold
Croatian: ↑ 49 puta
English: Treatment should be initiated at 300 mg (three sachets) twice daily for a period of three days and increased by 100 mg (one sachet) twice daily increments up to 600 mg twice daily over a period of no longer than 14 days.
Croatian: Liječenje treba početi dozom od 300 mg (tri vrećice) dva puta na dan tijekom tri dana, a potom dozu tijekom razdoblja ne dužeg od 14 dana povećavati za po 100 mg (jedna vrećica) dva puta na dan sve do 600 mg dva puta na dan.
English: • inflammation of the liver and yellowing of skin or whites of the eyes
Croatian: • upala jetre i žuta boja kože ili bjeloočnica • učestalije mokrenje
English: 500 q12h, 10
Croatian: 500 svakih 12h, 10 dana
English: - The active substance is ritonavir.
Croatian: Djelatna tvar je ritonavir.
English: Barrier or other non-hormonal methods of contraception should be considered when administering ritonavir at therapeutic or low doses as ritonavir is likely to reduce the effect and change the uterine bleeding profile when co-administered with estradiol-containing contraceptives.
Croatian: Pri primjeni ritonavira u terapijskim ili malim dozama treba razmotriti korištenje mehaničkih i ostalih nehormonskih metoda kontracepcije jer bi ritonavir vjerojatno oslabio djelovanje etinilestradiola i promijenio profil uterinog krvarenja kada bi se uzimao istodobno s kontraceptivima koji sadržavaju estradiol.
English: − pethidine, piroxicam, propoxyphene (used to relieve pain);
Croatian: − petidin, piroksikam, propoksifen (koriste se za ublažavanje boli);
English: Decreased R-warfarin levels may lead to reduced anticoagulation, therefore it is recommended that anticoagulation parameters are monitored when warfarin is coadministered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Croatian: Zbog sniženih razina R-varfarina može oslabiti antikoagulacijski učinak te se stoga preporučuje praćenje koagulacijskih parametara kada se varfarin daje istodobno s ritonavirom doziranim kao antiretrovirusnim lijekom ili kao farmakokinetičkim pojačivačem.
English: Amprenavir1 ↑ 64% ↑ 5 fold
Croatian: 100 svakih 12h Amprenavir1 ↑ 64% ↑ 5 puta
English: Norvir is also supplied as a powder for oral suspension containing 100 mg of ritonavir.
Croatian: Norvir dolazi i u obliku praška za oralnu suspenziju koji sadrži 100 mg ritonavira.
English: Didanosine 200 q12h
Croatian: Didanozin 200 svakih 12h
English: − Multipack containing 90 (3 bottles of 30) film-coated tablets
Croatian: Višestruko pakiranje sadrži 90 (3 boce sa 30) filmom obloženih tableta
English: Medicinal
Croatian: Liječenje
English: Norvir 100 mg film-coated tablets ritonavir
Croatian: Norvir 100 mg filmom obložene tablete ritonavir
English: Polyethylene/aluminium/polyethylene terephthalate foil sachet.
Croatian: Vrećica od polietilen/aluminij/polietilen tereftalatne folije. 30 vrećica u kutiji.
English: Increased plasma concentrations of avanafil (see section 4.4. and 4.5).
Croatian: Povišena koncentracija avanafila u plazmi (vidjeti dio 4.4 i 4.5).
English: A controlled study completed in 1996 with ritonavir as add-on therapy in HIV-1 infected patients extensively pre-treated with nucleoside analogues and baseline CD4 cell counts ≤ 100 cells/µl showed a reduction in mortality and AIDS defining events.
Croatian: Kontrolirano ispitivanje dovršeno 1996. godine, s ritonavirom kao dopunskim lijekom u liječenju bolesnika s HIV-1 infekcijama prethodno opsežno liječenima analozima nukleozida i s brojem CD4
English: − heart medicines (e.g. disopyramide, mexiletine and calcium channel antagonists such as amlodipine, diltiazem and nifedipine);
Croatian: − lijekove za srce (npr. dizopiramid, meksiletin i antagonisti kalcijevih kanala, poput amlodipina,
English: When ritonavir is used as a pharmacokinetic enhancer, full details on the warnings and precautions relevant to that particular PI must be considered, therefore the Summary of Product Characteristics, section 4.4, for the particular PI must be consulted to determine if the information below is applicable.
Croatian: Kada se ritonavir daje kao farmakokinetički pojačivač, nužno je potanko se upoznati sa svim upozorenjima i mjerama opreza za određeni IP te se stoga mora pročitati njihov Sažetak opisa svojstava lijeka i dio 4.4, da se vidi vrijede li niže navedene informacije.
English: Ritonavir should not be given as a pharmacokinetic enhancer to patients with decompensated liver disease (see section 4.3).
Croatian: Ritonavir se ne smije davati kao farmakokinetički pojačivač bolesnicima s dekompenziranom bolešću jetre (vidjeti dio 4.3).
English: • severe or life threatening skin reaction including blisters (Stevens Johnson syndrome, toxic epidermal necrolysis)
Croatian: uključujući pojavu mjehurića (StevensJohnsonov sindrom, toksična epidermalna nekroliza)
English: Medicinal product interactions - Ritonavir with antiretroviral agents other than protease inhibitors
Croatian: Interakcije lijekova - ritonavir s antiretroviroticima koji nisu inhibitori proteaza
English: 500 q12h ↓ 20% / ↑ 20% ↔
Croatian: 400 svakih 12h ↓ 82%
English: 526 mg (52.6 ml) twice daily
Croatian: 526 mg (52,6 ml) dva puta na dan
English: 20, single dose
Croatian: 20, jednokratna doza
English: − morphine and morphine-like medicines used to treat severe pain (e.g. methadone, fentanyl);
Croatian: − levotiroksin (koristi se za liječenje problema štitnjače); − morfin i njemu slične lijekove, koji se koriste za liječenje jake boli (npr. metadon, fentanil);
English: − Norvir is not a cure for HIV infection or AIDS.
Croatian: Norvir nije lijek za izlječenje HIV-infekcije ni AIDS-a.
English: 200 q12h, 2 days
Croatian: 200 svakih 12h, 2 dana
English: Measure the liquid a. Keep the syringe pointed up.
Croatian: Slika 3. Izmjerite tekućinu a.
English: Norvir is also supplied as a film-coated tablet containing 100 mg ritonavir.
Croatian: Norvir dolazi i u obliku filmom obloženih tableta koje sadrže 100 mg ritonavira.
English: Immunosupressants
Croatian: Imunosupresivi
English: Amiodarone, bepridil, dronedarone, encainide, flecanide, propafenone, quinidine
Croatian: Amiodaron, bepridil, dronedaron, enkainid, flekanid, propafenon, kinidin
English: HCV Direct Acting Antiviral
Croatian: Direktno djelujući antivirotici za liječenje HCV-a
English: You must not take Norvir with sildenafil if you suffer from pulmonary arterial hypertension (see also section 2.
Croatian: Ako bolujete od plućne arterijske hipertenzije, Norvir ne smijete uzimati istodobno sa sildenafilom (pogledajte i dio 2.
English: Ritonavir co-administration is likely to result in increased plasma concentrations of amiodarone, bepridil, dronedarone, encainide, flecainide, propafenone, and quinidine and is therefore contraindicated (see section 4.3).
Croatian: Istodobno primijenjeni ritonavir vjerojatno povećava koncentracije amiodarona, bepridila, dronedarona, enkainida, flekainida, propafenona i kinidina te je stoga je kontraindiciran (vidjeti dio 4.3).
English: 500 q12h ↓ 20% / ↑ 20% ↔ Dose alteration of sulfamethoxazole/trimethoprim during concomitant ritonavir therapy should not be necessary.
Croatian: 500 svakih 12h Mijenjanje doze sulfametoksazola/trimetoprima nije nužno pri njihovoj istodobnoj primjeni s ritonavirom.
English: Check the prescription label on the carton or call your doctor or pharmacist if you are not sure.
Croatian: Provjerite recept ili kontaktirajte Vašeg liječnika ili ljekarnika za informaciju o broju vrećica ako niste sigurni.
English: Pharmacokinetic enhancement by ritonavir is based on ritonavir's activity as a potent inhibitor of CYP3A- mediated metabolism.
Croatian: Ritonavir doziran kao farmakokinetički pojačivač Pospješivanje farmakokinetike pomoću ritonavira zasniva se na njegovoj aktivnosti kao snažnog inhibitora metabolizma putem CYP3A.
English: Delavirdine 400 q8h
Croatian: Delavirdin 400 svakih 8h 600 svakih 12h
English: − antidepressants (e.g. amitriptyline, desipramine, fluoxetine, imipramine, nefazodone,
Croatian: − antidepresive (npr. amitriptilin, dezipramin, fluoksetin, imipramin, nefazodon, nortriptilin,
English: Darunavir 600 mg twice daily with ritonavir 100 mg twice daily in antiretroviral treatment (ART) experienced patients.
Croatian: Darunavir 600 mg dva puta na dan s ritonavirom 100 mg dva puta na dan u bolesnika koji su već primali antiretrovirusnu terapiju (ART).
English: - Trazodone (a medicine for depression) as, unwanted effects like nausea, dizziness, low blood pressure and fainting can occur when taken with Norvir.
Croatian: − Trazodon (lijek za depresiju), jer se pri njegovu uzimanju s lijekom Norvir mogu javiti nuspojave poput mučnine, omaglice, niskog krvnog tlaka i nesvjestice.
English: Silica, colloidal anhydrous Polysorbate 80
Croatian: koloidni, bezvodni silicijev dioksid, polisorbat 80.
English: Based on cross-study comparison to 800 mg indinavir three times daily alone.
Croatian: Zasniva se na usporedbi među ispitivanjima s 800 mg indinavira triput na dan, u monoterapiji.
English: Also read the list of medicines under ‘Other medicines and Norvir' for use with certain other medicines which require special care.
Croatian: molimo pogledajte i popis lijekova u dijelu „Drugi lijekovi i Norvir“.
English: 800 q12h
Croatian: 800 svakih 12h
English: 300 q24h
Croatian: 300 svakih 24h
English: The co-administration of riociguat with Norvir is not recommended (see section 4.4 and refer to riociguat SmPC).
Croatian: Istodobna primjena riocigvata i lijeka Norvir se ne preporučuje (vidjeti dio 4.4 i Sažetak opisa svojstava lijeka za riocigvat).
English: 200 mg in the morning and 200 mg in the evening
Croatian: 200 mg ujutro i 200 mg navečer
English: Step 6.
Croatian: Korak 6.
English: For further dosage recommendations, refer to the product information of other protease inhibitors approved for co-administration with ritonavir.
Croatian: Za ostale preporuke o doziranju pročitati uputu o lijeku za druge inhibitore proteaza, odobrene za primjenu u kombinaciji s ritonavirom.
English: Sulfamethoxazole was co-administered with trimethoprim.
Croatian: 2.Sulfametoksazol se davao istodobno s trimetoprimom.
English: Very common Fatigue including asthenia, flushing, feeling hot
Croatian: Vrlo često Umor uključujući asteniju, crvenilo uz osjećaj vrućine
English: − antihistamines (e.g. loratidine, fexofenadine);
Croatian: − antihistaminike (npr. loratidin, feksofenadin);
English: Refer to the ceritinib SmPC for dosage adjustment recommendations.
Croatian: Vidjeti Sažetak opisa svojstava lijeka za ceritinib za preporuke vezane uz prilagodbu doze.
English: Pour the powder into the cup a. Tear open the sachet.
Croatian: Slika 5. Uspite prašak u čašu a.
English: Ritonavir inhibits CYP3A-mediated metabolism of ketoconazole.
Croatian: Ritonavir inhibira metabolizam ketokonazola posredovan enzimom CYP3A.
English: Ethinyl estradiol
Croatian: KG Knollstrasse
English: Each tablet contains 100 mg ritonavir.
Croatian: Jedna tableta sadrži 100 mg ritonavira.
English: Low doses of ritonavir have shown profound effects on the pharmacokinetics of other protease inhibitors (and other products metabolised by CYP3A4) and other protease inhibitors may influence the pharmacokinetics of ritonavir (see section 4.5).
Croatian: (i ostalih pripravaka koji se metaboliziraju putem CYP3A4), te da drugi inhibitori proteaza mogu utjecati na farmakokinetiku ritonavira (vidjeti dio 4.5).
English: 50, single dose
Croatian: 50, jednokratna doza
English: Norvir powder for oral suspension has a lingering aftertaste.
Croatian: Norvir prašak za oralnu suspenziju ostavlja okus u ustima neko vrijeme.
English: Dose of Coadministered Medicinal Product (mg)
Croatian: Doza istodobno primijenjenog lijeka (mg)
English: 600 q24h
Croatian: 600 svakih 24h
English: Co-administration of encorafenib and ritonavir should be avoided.
Croatian: Potrebno je izbjegavati istodobnu primjenu enkorafeniba i ritonavira.
English: Inform your doctor as soon as possible if you experience any symptoms that suggest an allergic reaction after taking Norvir such as rash, hives or breathing difficulties.
Croatian: Jave li se pri uzimanju lijeka Norvir bilo koji simptom koji upućuje na alergijsku reakciju, poput osipa, koprivnjače ili otežanog disanja, o tome što prije obavijestite svog liječnika.
English: (For caution on parenterally administered midazolam, see section 4.5.
Croatian: (Za mjere opreza pri parenteralnoj primjeni midazolama vidjeti dio
English: Each sachet of Norvir contains 100 mg ritonavir.
Croatian: Jedna vrećica lijeka Norvir sadrži 100 mg ritonavira.
English: Tel: +40 21 529 30 35
Croatian: AbbVie SRL Tel: +40 21 529 30 35
English: In intent to treat analyses, 72% and 36% of patients achieved reduction in plasma HIV-1 RNA of ≤ 400 copies/ml at Week 16 and 104, respectively.
Croatian: Intent-to-treat (ITT) analiza pokazala je da se broj kopija HIV-1 RNK smanjio na ≤ 400/ml u 72% bolesnika nakon 16 tjedana, a u 36% bolesnika nakon 104 tjedna.
English: Cl/F (L/h) 1 Values expressed as geometric means.
Croatian: 1 Vrijednosti izražene kao geometrijske srednje vrijednosti.
English: 10, single dose 600 q12h ↑ 153% ↑ 55% Inhibition of CYP3A and P-gp lead to increased plasma levels and pharmacodynamic effects of rivaroxaban which may lead to an increased bleeding risk.
Croatian: Inhibicija CYP3A i P-gp je rezultirala povećanjem razina u plazmi te povećanjem farmakodinamičkog učinka rivaroksabana što može dovesti do povećanog rizika od krvarenja.
English: c. The liquid may look cloudy - this is okay.
Croatian: Tekućina može biti mutna, ali to je uredu.
English: Lopinavir co-formulated with ritonavir (lopinavir/ritonavir) 400 mg/100 mg or 800 mg/200 mg. Saquinavir 1000 mg twice daily with ritonavir 100 mg twice daily in ART experienced patients.
Croatian: Lopinavir u formulaciji s ritonavirom (lopinavir/ritonavir) 400 mg/100 mg ili 800 mg/200 mg.
English: Concomitant use of avanafil or vardenafil with ritonavir is contraindicated (see section 4.3).
Croatian: Istodobna primjena avanafila ili vardenafila s ritonavirom je kontraindicirana (vidjeti dio 4.3).
English: c. Slowly pull the plunger back to the 10 ml mark - try not to pull any bubbles into the syringe (see Figure 8).
Croatian: Polako vucite klip do oznake od 10 ml pokušajte ne uvući mjehuriće u štrcaljku
English: Modest prolongation of the PR interval was also noted in subjects receiving ritonavir in the same study on Day 3.
Croatian: U ispitanika koji su primali ritonavir u istom je ispitivanju trećeg dana uočeno i umjereno produženje
English: Due to the risk of QTc prolongation associated with DM-6705, if co-administration of delamanid with ritonavir is considered necessary, very frequent ECG monitoring throughout the full delamanid treatment period is recommended (see section 4.4 and refer to the delamanid Summary of Product Characteristics).
Croatian: Zbog rizika od produženja QTc intervala povezanog s metabolitom DM-6705, ukoliko je nužna istodobna primjena delamanida i ritonavira, preporučuje se učestalo praćenje
English: − The tablet coating is composed of: hypromellose, titanium dioxide, macrogols, hydroxypropyl cellulose, talc, colloidal anhydrous silica, polysorbate 80.
Croatian: Film ovojnica: hipromeloza titanijev dioksid (E171) makrogoli hidroksipropilceluloza talk silicijev dioksid, koloidni, bezvodni polisorbat 80
English: Increased plasma concentrations of vardenafil (see section 4.4. and 4.5).
Croatian: Povišena koncentracija vardenafila u plazmi (vidjeti dio 4.4 i 4.5).
English: PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING NORVIR FILM-COATED TABLETS BOTTLE LABEL TEXT - 3 BOTTLES
Croatian: PODACI KOJI SE MORAJU NALAZITI NA UNUTARNJEM PAKIRANJU TEKST NA NALJEPNICI NA BOCI NORVIR FILMOM OBLOŽENIH TABLETA- 3 BOCE
English: Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
Croatian: Ritonavir doziran kao antiretrovirusni lijek ili kao farmakokinetički pojačivač inducira oksidaciju posredovanu enzimom CYP2C9 i glukuronidaciju, zbog čega se očekuje smanjenje koncentracije antikonvulziva u plazmi.
English: In a study completed in 1996 recruiting less advanced HIV-1 infected patients (CD4 200-500 cells/µl) without previous antiretroviral therapy, ritonavir in combination with zidovudine or alone reduced viral load in plasma and increased CD4 count.
Croatian: 200-500 stanica/µl) bez prethodnog antiretrovirusnog liječenja, ritonavir u kombinaciji sa zidovudinom i ritonavir u monoterapiji, smanjio je broj virusnih čestica u plazmi i povećao broj CD4
English: Based on cross-study comparison to 600 mg saquinavir three times daily alone.
Croatian: 4. Zasniva se na usporedbi među ispitivanjima sa 600 mg sakvinavira triput na dan, u monoterapiji.
English: Twice Daily Dose 300 mg/m2
Croatian: Doziranje dva puta na dan 300 mg/m²
English: The co-administration of vorapaxar with Norvir is not recommended (see section 4.4 and refer to the vorapaxar SmPC).
Croatian: Istodobna primjena vorapaksara i lijeka Norvir se ne preporučuje (vidjeti dio 4.4 i Sažetak opisa svojstava lijeka za vorapaksar).
English: For administration using a feeding tube follow the instructions in section ‘How do I take the correct dose of Norvir powder for oral suspension mixed with liquid?'
Croatian: Za primjenu putem cjevčice za hranjenje slijedite upute u dijelu „Kako uzeti točnu dozu
English: Very common Arthralgia and back pain Common Myositis, rhabdomyolysis, myalgia, myopathy/CPK increased
Croatian: Često Miozitis, rabdomioliza, mialgija, miopatija/povišenje CK
English: Place empty sachet in rubbish.
Croatian: Korak 9. Praznu vrećicu odložite u smeće.
English: 100 q24h
Croatian: 100 svakih 24h
English: You may also notice irregular uterine bleeding if you are taking this type of hormonal contraceptive with Norvir.
Croatian: Uzimate li tu vrstu hormonskog kontraceptiva i Norvir, možda primijetite da je i menstrualno krvarenje postalo neredovito.
English: - Colchicine (for gout) as Norvir may raise the blood levels of this medicine.
Croatian: Kolhicin (za liječenje gihta) jer Norvir može povisiti razine ovog lijeka u krvi.
English: − atovaquone, a medicine used to treat a certain type of pneumonia and malaria;
Croatian: − atovakon, lijek koji se koristi za liječenje određenih vrsta upale pluća i malarije; − buprenorfin, koji se koristi za liječenje kronične boli;
English: Twice Daily Dose 350 mg/m2
Croatian: Doziranje dva puta na dan 350 mg/m²
English: Adverse reactions of nausea, dizziness, hypotension and syncope have been observed in single dose interaction studies in healthy volunteers (see section 4.5)
Croatian: U ispitivanjima interakcija pri primjeni jednokratnih doza zdravim dobrovoljcima uočene su nuspojave poput mučnine, omaglice, hipotenzije i sinkope (vidjeti dio 4.5).
English: Co-administration of fosamprenavir with ritonavir in doses greater than 100 mg twice daily has not been clinically evaluated.
Croatian: Fosamprenavir Primjena fosamprenavira istodobno s ritonavirom u dozama većim od većim od 100 mg dva puta na dan nije klinički evaluirana.
English: Refer to the darunavir Summary of Product Characteristics for further information on once daily dosing in ART experienced patients.
Croatian: Za više informacija o doziranju jedanput na dan kod bolesnika koji su prethodno primali ART treba pročitati
English: HMG-CoA reductase inhibitors which are highly dependent on CYP3A metabolism, such as lovastatin and simvastatin, are expected to have markedly increased plasma concentrations when co-administered with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer.
Croatian: koji su izrazito ovisni o metabolizmu posredovanom enzimima CYP3A , poput lovastatina i simvastatina, znatno povećati pri njihovoj istodobnoj primjeni s ritonavirom doziranim kao antiretrovirusnim lijekom ili kao farmakokinetičkim pojačivačem.
English: b. Point the syringe into the mixing cup and slowly push the plunger to the correct ml for the dose (see Figure 10).
Croatian: Usmjerite štrcaljku u čašu za miješanje i polako potiskujte klip do točne doze u mililitrima
English: Thereby, increasing the risk of arrhythmias or other serious adverse reactions from these agents.
Croatian: Time se povećava rizik od aritmija i od ostalih ozbiljnih nuspojava tih lijekova.
English: 500 mg in the morning and 500 mg in the evening
Croatian: 500 mg ujutro i 500 mg navečer
English: - Bosentan, riociguat (used for pulmonary arterial hypertension) as Norvir may increase the blood levels of this medicine.
Croatian: − Bosentan, riocigvat (lijekovi za plućnu arterijsku hipertenziju) jer Norvir može povisiti razinu tog lijeka u krvi.
English: Dose of Coadministered Medicinal Products (mg)
Croatian: Doza istodobno primijenjeno g lijeka (mg)
English: Concomitant use of sildenafil for the treatment of erectile dysfunction, with ritonavir dosed as an antiretroviral agent or as a pharmacokinetic enhancer should be used with caution and in no instance should sildenafil doses exceed 25 mg in 48 hours (see also section 4.4).
Croatian: Pri primjeni sildenafila za liječenje erektilne disfunkcije istodobno s ritonavirom doziranim kao antiretrovirusnim lijekom ili kao farmakokinetičkim pojačivačem nužan je oprez, a sildenafil se ni u kojem slučaju ne smije davati u dozama većima od 25 mg u 48 sati
English: Method of administration
Croatian: Sustav organa
English: Tel: +39 06 928921
Croatian: AbbVie S.r.l. Tel: + 39 06 928921