FrancophonIA/ELRC3.0 huggingface dataset:
English: The dose for children and adolescents is calculated by body weight and is taken once daily as shown below:
Slovenian: Odmerek za otroke in mladostnike je izračunan glede na telesno težo ter se vzame enkrat na dan, kakor je prikazano v naslednji tabeli:
English: Insufficient numbers of elderly patients have been evaluated in clinical studies to determine whether they respond differently than younger patients.
Slovenian: V kliničnih študijah niso preučili zadostnega števila starejših bolnikov, da bi lahko ugotovili, ali se ti odzivajo drugače od mlajših bolnikov.
English: Tell your doctor immediately if you feel depressed, have suicidal thoughts or have strange thoughts (see section 4, Possible side effects).
Slovenian: Takoj povejte zdravniku, če se počutite depresivno, mislite na samomor ali imate čudne misli (glejte poglavje 4, Možni neželeni učinki).
English: Efavirenz has been studied in over 9,000 patients.
Slovenian: Efavirenz so preučevali pri več kot 9.000 bolnikih.
English: Aesica Queenborough Limited North Road, Queenborough Kent, ME11 5EL United Kingdom
Slovenian: Aesica Queenborough Limited North Road, Queenborough Kent, ME11 5EL Velika Britanija
English: Keep the medicine container with you so that you can easily describe what you have taken.
Slovenian: S seboj imejte embalažo zdravila, da boste lahko opisali, kaj ste zaužili.
English: It is recommended that HIV infected women do not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Slovenian: Priporočamo, da z virusom HIV okužene matere svojih otrok ne dojijo v nobenem primeru, da bi se izognile prenosu virusa HIV.
English: Therefore, efavirenz should not be given to children less than 3 months of age.
Slovenian: Zato se efavirenza ne sme dati otrokom, mlajšim od 3 mesecev.
English: Use a small container for mixing.
Slovenian: Za mešanje uporabite majhno posodo.
English: Make sure the child eats the full amount of the mixture of food and capsule contents.
Slovenian: Zagotovite, da je otrok pojedel vso mešanico hrane in vsebine kapsule.
English: Any inflammatory symptoms should be evaluated and treatment instituted when necessary.
Slovenian: Kakršnekoli vnetne simptome je potrebno obravnavati in uvesti zdravljenje, kadar je potrebno.
English: The clinical significance of these effects is not known.
Slovenian: Klinični pomen teh učinkov ni znan.
English: One patient experienced involuntary muscle contractions.
Slovenian: Pri enem bolniku so se pojavile nehotene mišične kontrakcije.
English: Efavirenz is highly bound (approximately 99.5 - 99.75%) to human plasma proteins, predominantly albumin.
Slovenian: Efavirenz se močno veže (približno 99,5 - 99,75 %) na človeške plazemske beljakovine, predvsem na albumin.
English: Tell your doctor if you notice any of the following side effects:
Slovenian: Zdravniku povejte, če opazite katerega koli od naslednjih neželenih učinkov:
English: Treatment of overdose with efavirenz should consist of general supportive measures, including monitoring of vital signs and observation of the patient's clinical status.
Slovenian: Zdravljenje prevelikega odmerjanja z efavirenzem naj vključuje splošne podporne ukrepe, vključno s spremljanjem življenjskih znakov in opazovanjem bolnikovega kliničnega stanja.
English: Some patients accidentally taking 600 mg twice daily have reported increased nervous system symptoms.
Slovenian: Nekaj bolnikov, ki so pomotoma jemali 600 mg dvakrat na dan, je poročalo o večjem pojavljanju simptomov živčnega sistema.
English: Other interactions: efavirenz does not bind to cannabinoid receptors.
Slovenian: Druge interakcije: efavirenz se ne veže na kanabinoidne receptorje.
English: Increases in bupropion dosage should be guided by clinical response, but the maximum recommended dose of bupropion should not be exceeded.
Slovenian: Odmerek bupropiona je treba povečati glede na klinični odziv, vendar največji priporočeni odmerek bupropiona ne sme biti presežen.
English: if your doctor has told you that you have high or low levels of electrolytes such as potassium or magnesium in your blood.
Slovenian: če vam je zdravnik povedal, da imate visok ali nizek nivo elektrolitov, kot sta kalij ali magnezij, v krvi.
English: This decrease in atazanavir Cmin might negatively impact the efficacy of atazanavir.
Slovenian: To zmanjšanje Cmin atazanavirja lahko negativno vpliva na učinkovitost atazanavirja.
English: 24 weeks
Slovenian: 24 tednov
English: In controlled trials, the frequency of specific serious psychiatric events were:
Slovenian: V nadzorovanih preskušanjih je bila pogostnost določenih resnih psihiatričnih neželenih učinkov sledeča:
English: Caution is warranted since this dose adjustment might be insufficient in some patients.
Slovenian: Previdnost je utemeljena, saj je lahko tako prilagajanje odmerkov pri nekaterih bolnikih nezadostno.
English: Skin and subcutaneous tissue disorders very common rash (11.6%)*
Slovenian: Bolezni kože in podkožja zelo pogosti izpuščaj (11,6 %)*
English: 5 SUSTIVA capsules must be opened carefully over the food container, as described in steps 6-7, so that the contents do not spill.
Slovenian: 5 Previdno odprite kapsule SUSTIVA nad posodo s hrano, kakor je opisano v korakih 6-7, da ne raztresete vsebine.
English: What SUSTIVA is and what it is used for 2.
Slovenian: Kaj je zdravilo SUSTIVA in za kaj ga uporabljamo 2.
English: Patients should be informed that if they do occur, these common symptoms are likely to improve with continued therapy and are not predictive of subsequent onset of any of the less frequent psychiatric symptoms.
Slovenian: Bolnikom je treba povedati, da se bodo ti običajni simptomi, če se pojavijo, najverjetneje z nadaljevanjem terapije izboljšali, in da ne napovedujejo kasnejšega pojava katerega od manj pogostih psihiatričnih simptomov.
English: For a summary of clinical and pharmacodynamic information, see section 5.1.
Slovenian: Za povzetek kliničnih in farmakodinamičnih informacij glejte poglavje 5.1.
English: This may make some side effects (for example, dizziness, drowsiness) less troublesome.
Slovenian: Tako so lahko nekateri neželeni učinki (na primer omotica, zaspanost) manj moteči.
English: Responder rates were highest in patients who switched NRTIs.
Slovenian: Deleži odziva so bili najvišji pri bolnikih, ki so zamenjali NRTI.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web-portal.
Slovenian: Redno posodobljena poročila o varnosti zdravila (PSUR) Zahteve glede predložitve rednega posodobljenega poročila o varnosti zdravila za to zdravilo so določene v seznamu referenčnih datumov EU (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES, in vseh kasnejših posodobitvah, objavljenih na evropskem spletnem portalu o zdravilih.
English: Once you start taking SUSTIVA, look out for:
Slovenian: Ko začnete jemati zdravilo SUSTIVA, bodite pozorni na:
English: - severe disturbances of electrolyte balance e.g. hypokalemia or hypomagnesemia.
Slovenian: - hudo motnjo elektrolitskega ravnotežja, npr. hipokaliemijo ali hipomagnezemijo.
English: 9 If the daily dose consists of more than one capsule, follow steps 5-8 for each capsule.
Slovenian: 9 Če za dnevni odmerek potrebujete več kapsul, ponovite korake 5-8 za vsako kapsulo.
English: Patients should be monitored for seizure control.
Slovenian: Bolnike je treba nadzorovati glede krčev.
English: unexplained feelings of distress not associated with hallucinations, but it may be difficult to think clearly or sensibly suicide
Slovenian: nepojasnjeni občutki stiske, ki niso povezani s halucinacijami, lahko pa povzročajo težave pri jasnem ali razumnem razmišljanju samomor.
English: if you have a history of liver disease, including active chronic hepatitis.
Slovenian: če ste v preteklosti imeli bolezen jeter, vključno z aktivnim kroničnim hepatitisom.
English: QTc Prolongation
Slovenian: Podaljšanje intervala QTc
English: The mechanism of tumour formation and the potential relevance for humans are not known.
Slovenian: Mehanizem nastanka tumorjev in možen pomen za ljudi nista znana.
English: Patients who cannot swallow
Slovenian: Bolniki, ki zdravila ne morejo pogoltniti
English: rare photoallergic dermatitis
Slovenian: redki fotoalergijski dermatitis‡
English: It is important to tell your doctor or pharmacist if you are taking any of the following:
Slovenian: Pomembno je, da zdravniku ali farmacevtu poveste, če jemljete kar koli od naštetega:
English: if you have a heart disorder, such as abnormal electrical signal called prolongation of the QT interval.
Slovenian: če imate motnjo v delovanju srca, kot je nenormalen električni signal, ki se imenuje podaljšanje intervala QT.
English: Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines.
Slovenian: Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo.
English: Dosing at bedtime seems to improve the tolerability of these symptoms and can be recommended during the first weeks of therapy and in patients who continue to experience these symptoms (see section 4.2).
Slovenian: Kaže, da odmerjanje pred spanjem izboljša prenašanje teh simptomov in ga lahko priporočamo v prvih tednih zdravljenja ter pri bolnikih, pri katerih se ti simptomi nadaljujejo (glejte poglavje 4.2).
English: Confirmatory testing by a more specific method such as gas chromatography/mass spectrometry is recommended in such cases.
Slovenian: V teh primerih je priporočljiva uporaba bolj specifičnih potrditvenih metod, kot sta plinska kromatografija/masna spektrometrija.
English: If available, 90% or 95% confidence intervals are shown in parentheses.
Slovenian: 90-odstotni ali 95-odstotni intervali zaupanja so prikazani v oklepajih, če so na voljo.
English: If you are pregnant, you should take SUSTIVA only if you and your doctor decide it is clearly needed.
Slovenian: Če ste noseči, lahko zdravilo SUSTIVA jemljete le, če se z zdravnikom skupaj odločita, da je to nujno potrebno.
English: Use in the paediatric population
Slovenian: Uporaba pri pediatrični populaciji
English: Your doctor has prescribed SUSTIVA for you because you have HIV infection.
Slovenian: Zdravnik vam je predpisal zdravilo SUSTIVA, ker ste okuženi z virusom HIV.
English: Patients with severe hepatic impairment (Child Pugh Class C) (see section 5.2).
Slovenian: Bolniki s hudo okvaro jeter (razred C po Child Pugh-u) (glejte poglavje 5.2).
English: 14 Have the child eat the full amount again (illustration f).
Slovenian: 14 Znova dajte otroku vso količino hrane (slika f).
English: Try not to miss a dose.
Slovenian: Trudite se, da ne bi izpustili nobenega odmerka.
English: Not recommended as the exposure to both PIs is expected to be significantly decreased.
Slovenian: Ne priporočamo, ker lahko pričakujemo, da bi s tem pomembno zmanjšali izpostavitev obema ZP.
English: Frequency is defined using the following convention: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); or very rare (< 1/10,000).
Slovenian: Pogostnost je definirana z uporabo sledečega dogovora: zelo pogosti (≥ 1/10); pogosti (≥ 1/100, < 1/10); občasni (≥ 1/1.000, < 1/100); redki (≥ 1/10.000, < 1/1.000) ali zelo redki (< 1/10.000).
English: Instructions for capsule sprinkle method:
Slovenian: Navodila za uporabo metode posutja kapsule:
English: astemizole or terfenadine (used to treat allergy symptoms)
Slovenian: astemizol ali terfenadin (za zdravljenje alergijskih simptomov)
English: The incidence of erythema multiforme or Stevens-Johnson syndrome was approximately 0.1%.
Slovenian: Pojavnost multiformnega eritema ali Stevens-Johnsonovega sindroma je bila približno 0,1 %.
English: †These adverse reactions were identified through post-marketing surveillance; however, the frequencies were determined using data from 16 clinical trials (n=3,969).
Slovenian: †Te neželene učinke so odkrili med spremljanjem zdravila na trgu; vendar pa so bile pogostnosti določene z uporabo podatkov iz 16 kliničnih preskušanj (n = 3.969).
English: What you need to know before you take SUSTIVA 3.
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo SUSTIVA 3.
English: When treating HIV infection, it is not always possible to tell whether some of the unwanted effects are caused by SUSTIVA or by other medicines that you are taking at the same time, or by the HIV disease itself.
Slovenian: Pri zdravljenju okužbe s HIV je včasih težko reči, ali se nekateri neželeni učinki pojavijo zaradi zdravila SUSTIVA, drugih zdravil, ki jih jemljete sočasno, ali zaradi bolezni HIV same.
English: Despite the decrease in buprenorphine exposure, no patients exhibited withdrawal symptoms.
Slovenian: Kljub zmanjšanju izpostavljenosti buprenorfinu se pri bolnikih niso pokazali odtegnitveni simptomi.
English: For the drug-drug interaction with etonogestrel implant, the PRAC noted the available data from 16 case reports and the published literature articles by Vieira et al., 2014 and Chappel et al., 2017.
Slovenian: Odbor PRAC je za medsebojno delovanje zdravil z vsadkom etonogestrela upošteval razpoložljive podatke iz 16 poročil o primerih in iz člankov, objavljenih v literaturi, avtorjev Vieira et al., 2014, in Chappel et al., 2017.
English: Annex IV Scientific conclusions and grounds for the variation to the terms of the marketing authorisation(s)
Slovenian: Priloga IV ZNANSTVENI ZAKLJUČKI IN PODLAGA ZA SPREMEMBO POGOJEV DOVOLJENJA (DOVOLJENJ) ZA PROMET Z ZDRAVILOM
English: Opening the capsule and taking the contents with a small amount of food may be considered for children who cannot swallow the hard capsule.
Slovenian: Odpiranje kapsule in jemanje vsebine z majhno količino hrane je lahko rešitev za otroke, ki ne morejo pogoltniti trdih kapsul.
English: In such patients, interruption or discontinuation of treatment must be considered (see section 4.8).
Slovenian: Pri teh bolnikih je potrebno razmisliti o prekinitvi oziroma prenehanju zdravljenja (glejte poglavje 4.8).
English: any signs of skin rash.
Slovenian: kateri koli znak kožnega izpuščaja.
English: The incidence of neural tube defects in the general population ranges from 0.5-1 case per 1,000 live births.
Slovenian: Pojavnost okvar nevralne cevi v splošni populaciji se giblje v razponu od 0,5 do 1 primer na 1.000 živorojenih otrok.
English: If you do miss a dose, take the next dose as soon as possible, but do not take a double dose to make up for a forgotten dose.
Slovenian: Če kljub temu izpustite odmerek, vzemite naslednji odmerek takoj, ko je mogoče, vendar ne vzemite dvojnega odmerka, da bi nadomestili izpuščenega.
English: If you have severe liver disease, do not take SUSTIVA (see section 2, Do not take SUSTIVA).
Slovenian: Če imate hudo bolezen jeter, ne jemljite zdravila SUSTIVA (glejte poglavje 2, Ne jemljite zdravila SUSTIVA).
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 28 May 1999
Slovenian: Datum prve odobritve: 28. maj 1999
English: Similar elevations were seen in patients treated with control regimens (5% after long-term treatment).
Slovenian: Podobna povišanja so opazili tudi pri bolnikih na kontrolnem režimu (5 % po dolgotrajnem zdravljenju).
English: The standard doses of NRTIs given every 12 hours were used in each of these studies.
Slovenian: V vsaki od teh študij so uporabili standardne odmerke NRTI-jev na vsakih 12 ur.
English: Contraindications of concomitant use
Slovenian: Kontraindikacije za sočasno uporabo
English: If any antiretroviral medicinal product in a combination regimen is interrupted because of suspected intolerance, serious consideration should be given to simultaneous discontinuation of all antiretroviral medicinal products.
Slovenian: Če bolnik katero od protiretrovirusnih zdravil v kombiniranem režimu preneha jemati zaradi suma intolerance, je treba resno premisliti o istočasnem prenehanju jemanja vseh protiretrovirusnih zdravil.
English: This medicine is not a cure for HIV infection and you may continue to develop infections or other illnesses associated with HIV disease.
Slovenian: To zdravilo ne pozdravi okužbe s HIV in pri vas se bodo lahko še naprej pojavljale okužbe ali druge bolezni, povezane z boleznijo HIV.
English: Clinical experience in controlled studies with combinations including didanosine or zalcitabine is limited.
Slovenian: Klinične izkušnje iz nadzorovanih študij s kombinacijami zdravil, ki so vključevale didanozin ali zalcitabin, so omejene.
English: What SUSTIVA is and what it is used for
Slovenian: Kaj je zdravilo SUSTIVA in za kaj ga uporabljamo
English: The doctor may also recommend this method of taking SUSTIVA for adults who cannot swallow capsules.
Slovenian: Zdravnik lahko takšen način uporabe zdravila SUSTIVA priporoči tudi odraslim osebam, ki ne morejo pogoltniti kapsul.
English: Verapamil, Felodipine, Nifedipine and Nicardipine
Slovenian: verapamil, felodipin, nifedipin in nikardipin
English: if you have a heart condition, such as changes in the rhythm or rate of the heart beat, a slow heart beat, or severe heart disease.
Slovenian: če imate bolezen srca, kot so sprememba ritma ali hitrosti bitja srca, počasen srčni utrip ali hudo bolezen srca.
English: Patients with: - a family history of sudden death or of congenital prolongation of the QTc interval on electrocardiograms, or with any other clinical condition known to prolong the QTc interval.
Slovenian: Bolniki z/s: - družinsko anamnezo nenadne smrti ali prirojenega podaljšanja intervala QTc na elektrokardiogramu ali s katerim koli drugim kliničnim stanjem, za katerega je znano, da podaljša interval QTc.
English: Efavirenz may remain in your blood for a time after therapy is stopped.
Slovenian: Efavirenz lahko ostane v krvi še nekaj časa po prenehanju zdravljenja.
English: A positive relationship between efavirenz concentration and QTc prolongation was observed.
Slovenian: Ugotovili so pozitivno povezavo med koncentracijo efavirenza in podaljšanjem intervala QTc.
English: Table 1: Paediatric dose to be administered once daily*
Slovenian: Preglednica 1: Pediatrični odmerki za uporabo enkrat na dan*
English: - severe depression - suicidal ideation - non-fatal suicide attempts - aggressive behaviour - paranoid reactions - manic reactions
Slovenian: - huda oblika depresije - misel na samomor - samomorilni poskusi (ne smrtni) - agresivno vedenje - paranoidne reakcije - manične reakcije
English: Eighty-seven percent of patients had received prior antiretroviral therapy.
Slovenian: Sedeminosemdeset odstotkov bolnikov se je že prej zdravilo s protiretrovirusnimi zdravili.
English: This proportion is approximately 3-fold higher than the nonprotein-bound (free) fraction of efavirenz in plasma.
Slovenian: Ta delež je približno 3-krat višji od frakcije efavirenza v plazmi, ki ni vezana na beljakovine (prosta frakcija).
English: if you have severe liver disease.
Slovenian: če imate hudo bolezen jeter.
English: A causal relationship of these events to the use of efavirenz has not been established, and the denominator is unknown.
Slovenian: Vzročna povezava med temi dogodki in uporabo efavirenza ni bila ugotovljena in tudi skupni imenovalec ni znan.
English: You must not take SUSTIVA with certain medicines.
Slovenian: Zdravila SUSTIVA ne smete jemati skupaj z določenimi zdravili.
English: Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Slovenian: Znaki osteonekroze so togost sklepa, bolečnost in bolečine (zlasti v kolku, kolenu in rami) in težave z gibljivostjo.
English: Very common (affects more than 1 user in 10) skin rash
Slovenian: Zelo pogosti (pojavijo se pri več kot 1 od 10 bolnikov) kožni izpuščaj
English: Patients should be advised that if they experience symptoms such as severe depression, psychosis or suicidal ideation, they should contact their doctor immediately to assess the possibility that the symptoms may be related to the use of efavirenz, and if so, to determine whether the risks of continued therapy outweigh the benefits (see section 4.8).
Slovenian: Bolnikom je treba svetovati, naj se v primeru pojava simptomov, kot so huda oblika depresije, psihoza ali misel na samomor, nemudoma posvetujejo s svojim zdravnikom, ki bo ocenil, ali so simptomi lahko povezani z jemanjem efavirenza, in odločil, ali je tveganje nadaljevanja zdravljenja z efavirenzem večje od koristi (glejte poglavje 4.8).
English: You can still pass on HIV when taking this medicine, although the risk is lowered by effective antiretroviral therapy.
Slovenian: Kljub jemanju tega zdravila lahko še vedno s HIV okužite druge osebe, čeprav je tveganje zmanjšano z učinkovitim protiretrovirusnim zdravljenjem.
English: Patients should be instructed that if they experience these symptoms they should avoid potentially hazardous tasks such as driving or operating machinery.
Slovenian: Bolnikom je treba naročiti, naj se v primeru teh simptomov izogibajo potencialno nevarnim opravilom, kakršna sta vožnja ali upravljanje strojev.
English: In patients treated with other medicinal products associated with liver toxicity, monitoring of liver enzymes is also recommended.
Slovenian: Pri bolnikih, ki se zdravijo z drugimi zdravili, ki so toksična za jetra, prav tako priporočamo spremljanje jetrnih encimov.
English: For children who are not able to swallow the capsules, the doctor may recommend opening the hard capsule and mixing the contents with a small amount (1-2 teaspoons) of food (e.g., yogurt ).
Slovenian: Za otroke, ki ne morejo pogoltniti kapsul, lahko zdravnik priporoči, da odprete trdo kapsulo in njeno vsebino zmešate z majhno količino (1-2 kavni žlički) hrane (npr. jogurta).
English: Your doctor may conduct blood tests in order to check how well your liver is working or may switch you to another medicine.
Slovenian: Zdravnik bo morda naročil krvne teste, da bo preveril, kako dobro delujejo vaša jetra, ali pa vam bo zamenjal zdravilo.
English: Pharmacokinetic studies have not been performed in the elderly.
Slovenian: Farmakokinetičnih študij pri starejših bolnikih še niso opravili.
English: posaconazole.
Slovenian: posakonazol.
English: These immunosuppressants are not anticipated to affect exposure of efavirenz.
Slovenian: Pri teh imunosupresivih ne pričakujemo, da vplivajo na izpostavitev efavirenzu.
English: Efavirenz is a NNRTI of HIV-1.
Slovenian: Efavirenz je NNRTI HIV-1.
English: Efavirenz should not be used during pregnancy, unless the patient's clinical condition requires such treatment.
Slovenian: V nosečnosti se efavirenza ne sme uporabljati, razen če zdravstveno stanje bolnice zahteva tovrstno zdravljenje.
English: Ketoconazole and other imidazole antifungals
Slovenian: ketokonazol in drugi imidazolski antimikotiki
English: The dose for adults is 600 mg once daily.
Slovenian: Odmerek za odrasle je 600 mg enkrat na dan.
English: How to take SUSTIVA 4.
Slovenian: Kako jemati zdravilo SUSTIVA 4.
English: Neither aluminium/magnesium hydroxide antacids nor famotidine altered the absorption of efavirenz.
Slovenian: Niti aluminijevi/magnezijevi hidroksidni antacidi niti famotidin niso spremenili absorpcije efavirenza.
English: Hypromellose (E464)
Slovenian: Hipromeloza (E464)
English: Although limited data suggest that females as well as Asian and Pacific Island patients may have higher exposure to efavirenz, they do not appear to be less tolerant of efavirenz.
Slovenian: Čeprav malo podatkov kaže, da je lahko tako pri ženskah kot pri bolnikih iz Azije ali s Pacifiških otokov izpostavljenost efavirenzu večja, izgleda da ti bolniki zdravila ne prenašajo nič slabše.
English: While the carcinogenic potential in humans is unknown, these data suggest that the clinical benefit of efavirenz outweighs the potential carcinogenic risk to humans.
Slovenian: Čeprav potencialna karcinogenost za ljudi ni znana, podatki nakazujejo, da klinični učinek efavirenza odtehta možno tveganje za karcinogenost pri ljudeh.