FrancophonIA/ELRC3.0 huggingface dataset:
English: Capsule shell body 200 mg
Icelandic: Hylkisbotn 200 mg
English: The frequency of treatment emergent hepatitis or transaminase elevations in co-infected patients was comparable between atazanavir and comparator regimens (see section 4.4).
Icelandic: B eða C var sambærileg milli atazanavírs og samanburðar meðferðarinnar (sjá kafla 4.4).
English: ACID REDUCING AGENTS H2-Receptor antagonists
Icelandic: H2-viðtakablokkar
English: Administration of atazanavir with ritonavir with either a light or a high-fat meal decreased the coefficient of variation of AUC and Cmax by approximately 25% compared to the fasting state.
Icelandic: Gjöf atazanavírs með rítónavíri annaðhvort með léttri eða fituríkri máltíð minnkaði fráviksstuðull AUC og Cmax um u.þ.b.
English: Antiretroviral treatment experienced adult patients
Icelandic: Fullorðnir sjúklingar sem hafa fengið meðferð með andretróveirulyfjum
English: CD4 Mean Change from Baseline, cells/mm by Baseline Characteristic
Icelandic: CD4 Meðalbreyting frá upphafsgildi, frumur/mm3
English: PVC/PVDC/Aluminium blisters containing 60, 60 x 1 (unit dose) capsules.
Icelandic: PVC/PVDC/ álþynnur sem innihalda 60, 60 x 1 (stakskammtur) hylki.
English: In antiretroviral experienced adult patients
Icelandic: Sjúklingar með langvinna lifrarbólgu
English: Pravastatin
Icelandic: Breyta
English: ANTIPSYCHOTICS Quetiapine
Icelandic: GEÐROFSLYF Quetiapín
English: Capsule shell cap 200 mg
Icelandic: Hylkislok 200 mg
English: (atazanavir/ritonavir)
Icelandic: (Hypericum perforatum)
English: common: ocular icterus
Icelandic: algengar: gul augnhvíta
English: In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant Summary of Product Characteristics for these medicinal products (see section 4.8).
Icelandic: B eða C sem fá samsetta meðferð með andretróveirulyfjum eru í aukinni hættu á að fá alvarleg og hugsanlega lífshættuleg viðbrögð í lifur, sjá kafla einnig Samantekt á eiginleikum þessara lyfja (sjá kafla 4.8).
English: However, Atazanavir Mylan is not recommended in patients undergoing haemodialysis (see sections 4.2 and 5.2).
Icelandic: Mylan ekki ráðlagt hjá sjúklingum sem gangast undir blóðskilun (sjá kafla 4.2 og 5.2).
English: Co-administration of Atazanavir Mylan with proton pump inhibitors is not recommended (see section 4.5).
Icelandic: Ekki er ráðlagt að gefa Atazanavir Mylan samtímis prótónpumpuhemlum (sjá kafla 4.5).
English: Co-administration of nevirapine and atazanavir is not recommended (see section 4.4)
Icelandic: Ekki er mælt með samhliða gjöf nevírapíns og atazanavírs (sjá kafla 4.4)
English: uncommon: hypertension
Icelandic: sjaldgæfar: háþrýstingur
English: Midazolam and triazolam are extensively metabolised by CYP3A4.
Icelandic: Mídazólam og tríazólam umbrotna aðallega fyrir tilstilli CYP3A4.
English: Pharmacotherapeutic group: Antivirals for systemic use, protease inhibitors, ATC code: J05AE08
Icelandic: Veirulyf til altækrar notkunar (systemic use), próteasahemill, ATC flokkur:
English: Atazanavir Mylan once daily dose ritonavir once daily dose a
Icelandic: Mylan skammtur einu sinni á dag rítónavír skammtur einu sinni á daga
English: The capsules are axially printed with ‘MYLAN' over ‘AR300' in black ink on cap and body.
Icelandic: Áslæg prentun er á hylkinu sem er merkt með „MYLAN“ fyrir ofan „AR300“ með svörtu bleki á lokið og botninn.
English: uncommon: muscle atrophy, arthralgia, myalgia; rare: myopathy
Icelandic: sjaldgæfar: vöðvarýrnun, liðverkir, vöðvaþrautir mjög sjaldgæfar:
English: (range: 100 to 1157 cells/ mm 3) and mean baseline plasma HIV 1 RNA was 4.09 log10 copies/ml (range: 3.28 to 5.00 log10 copies/ml).
Icelandic: Hjá sjúklingum sem höfðu fengið meðferð með andretróveirulyfjum áður var meðalupphafsgildi CD4 522 frumur/mm3 (á bilinu:100-1.157 frumur/mm3) og meðalupphafsgildi HIV 1 RNA í plasma 4,09 log10 eintök/ml (á bilinu: 3,28-5,00 log10 eintök/ml).
English: Table 6: Efficacy Outcomes at Week 48
Icelandic: 96 voru útilokaðir frá greiningu í viku
English: There is no specific antidote for overdose with atazanavir.
Icelandic: Ekkert sértækt mótefni er við ofskömmtun með atazanavíri.
English: Hard capsule
Icelandic: 1 hörð hylki
English: In female mice, atazanavir exposure at a dose that produced single-cell necrosis was 12 times the exposure in humans given 400 mg once daily.
Icelandic: Þéttni atazanavírs í skömmtum sem ollu einstaka lifrarfrumudrepi hjá kvenmúsum var 12 sinnum meiri en í mönnum við ráðlagðan skammt.
English: Indinavir
Icelandic: Indínavír
English: Co-administration with atazanavir with ritonavir warrants clinical monitoring for sedation and cognitive effects.
Icelandic: Samhliða gjöf atazanavírs ásamt rítónavíri krefst klínísks eftirlits vegna slævandi áhrifa og áhrifa á skilvitlega starfsemi.
English: INSTRUCTIONS ON USE
Icelandic: Ráðlagt er að fylgjast
English: Diltiazem 180 mg once daily
Icelandic: Diltiazem 180 mg einu sinni á dag (atazanavír 400 mg einu sinni á dag)
English: The mechanism of nevirapine/atazanavir interaction is CYP3A4 induction.
Icelandic: Verkunarháttur milliverkunar nevírapín/atazanavír er CYP3A4 virkjun.
English: Atazanavir and fluconazole concentrations were not significantly modified when Atazanavir /ritonavir was co-administered with fluconazole.
Icelandic: Engin marktæk breyting varð á þéttni atazanavírs og flúkónazóls þegar atazanavír/rítónavír var gefið ásamt flúkónazól.
English: The capsules are axially printed with ‘MYLAN' over ‘AR200' in black ink on cap and body.
Icelandic: Áslæg prentun er á hylkinu sem er merkt með „MYLAN“ fyrir ofan „AR200“ með svörtu bleki á lokið og botninn.
English: Lovastatin
Icelandic: Bepridíl
English: How to store Atazanavir Mylan
Icelandic: 3. Hvernig nota á Atazanavir Mylan
English: common: fatigue; uncommon: chest pain, malaise, pyrexia, asthenia; rare: gait disturbance a These adverse reactions were identified through post-marketing surveillance, however, the frequencies were estimated from a statistical calculation based on the total number of patients exposed to atazanavir in randomised controlled and other available clinical trials (n = 2321).
Icelandic: a Þessar aukaverkanir komu fram eftir markaðssetningu, hins vegar var tíðnin metin með tölfræðiútreikningum byggðum á heildarfjölda sjúklinga sem fengu atazanavír í slembuðum samanburðarrannsóknum og öðrum tiltækum klínískum rannsóknum (n = 2.321).
English: Table 5: Efficacy Outcomes in Study 138
Icelandic: Niðurstöður verkunar (í rannsókn 138) a
English: The mechanism of the clarithromycin/atazanavir interaction is CYP3A4 inhibition.
Icelandic: Verkunarháttur milliverkunar claritrómýcin/atazanavír er CYP3A4 hömlun.
English: Capsule shell body 150 mg
Icelandic: Hylkisbotn 150 mg
English: In antiretroviral treatment experienced patients from Studies 009, 043, and 045, 100 isolates from patients designated as virological failures on therapy that included either atazanavir, atazanavir + ritonavir, or atazanavir + saquinavir were determined to have developed resistance to atazanavir.
Icelandic: Í 100 stofnum frá sjúklingum þar sem meðferð með veirueyðandi lyfjum hafði ekki skilað viðunandi árangri með annaðhvort atazanavíri, atazanavíri+rítónavír, eða atazanavíri+saquinavíri var ónæmi fyrir atazanavíri staðfest.
English: Iron oxide yellow (E172) Titanium dioxide (E171) Patent blue V (E131) Gelatin
Icelandic: Gult járnoxíð (E172) Títantvíoxíð (E171) Patentblátt V (E131) Gelatína
English: Store below 25°C.
Icelandic: Þéttni í 24 klst.
English: Capsule shell cap 150 mg
Icelandic: Hylkislok 150 mg
English: Medicinal products by therapeutic area
Icelandic: Lyf eftir meðferðarsviðum
English: Co-administration of atorvastatin with atazanavir is not recommended.
Icelandic: Samhliða gjöf atorvastatíns og atazanavírs er ekki ráðlögð.
English: During attempts to overcome the decreased exposure by increasing the dose of atazanavir or other protease inhibitors with ritonavir, a high frequency of liver reactions was seen.
Icelandic: Þegar skammtar atazanavír eða annarra próteasahemla með rítónavíri voru auknir í tilraunum til að vinna bug á minnkaðri útsetningu varð vart við hækkaða tíðni aukaverkana á lifur
English: Iron oxide red (E172) Titanium dioxide (E171) Patent blue V (E131) Gelatin
Icelandic: Rautt járnoxíð (E172) Títantvíoxíð (E171) Patentblátt V (E131) Gelatína
English: Cardiac monitoring is recommended based on the presence of clinical findings (e.g., bradycardia).
Icelandic: Ráðlagt er að fylgjast með hjartastarfsemi á grundvelli klínískra upplýsinga (t.d. hægslætti).
English: There are no pharmacokinetic data available for atazanavir with ritonavir in patients with renal insufficiency.
Icelandic: Engar upplýsingar um lyfjahvörf atazanavír ásamt rítónavír hjá sjúklingum með skerta nýrnastarfsemi liggja fyrir.
English: Atazanavir Cmax ↔6% (↓7% ↑20%)
Icelandic: Atazanavír Cmax ↔6% (↓7%
English: All patients HIV RNA <400 copies/ml, %
Icelandic: HIV RNA <400 eintök/ml, % a Allir sjúklingar
English: Age/gender
Icelandic: Aldur/kyn
English: 50 to <100 cells/mm
Icelandic: 50 til <100 frumur/mm3 76 (n=45)
English: Atazanavir Mylan 200 mg hard capsules
Icelandic: Mylan 200 mg hörð hylki
English: Capsules/ritonavir (300 mg/100 mg once daily) n=25
Icelandic: ATV/RTVb (300 mg/ 100 mg einu sinni á dag) n=120
English: Of the 60 isolates from patients treated with either atazanavir or atazanavir + ritonavir, 18 (30%) displayed the I50L phenotype previously described in naive patients.
Icelandic: Af 60 stofnum frá sjúklingum sem fengu atazanavír eða atazanavír+rítónavír, sýndu 18 (30%) I50L svipgerð sem áður var lýst hjá sjúklingum sem ekki höfðu verið á meðferð með andretróveirulyfjum, þetta kom fram í rannsóknum 009, 043 og 045 hjá sjúklingum sem vanir voru meðferð með andretróveirulyfjum.
English: Atazanavir should be discontinued if severe rash develops.
Icelandic: Hætta á notkun atazanavírs ef veruleg útbrot koma fram.
English: Atazanavir Mylan 300 mg hard capsules atazanavir
Icelandic: Mylan 300 mg hörð hylki atazanavír
English: Each hard capsule contains 150 mg of atazanavir (as sulphate).
Icelandic: Hvert hart hylki inniheldur 150 mg af atazanavíri (sem súlfat).
English: Atazanavir (pm): all administered with food
Icelandic: Atazanavír (e.h.): gefið með mat
English: ANTIMYCOBACTERIAL
Icelandic: Kalíumhýdroxíð
English: The mechanism of interaction is decreased solubility of atazanavir as intra-gastric pH increases with H2-blockers.
Icelandic: Verkunarháttur milliverkana er sá að með auknu pH í maga af völdum H2viðtakablokka dregur úr leysanleika atazanavírs
English: The Summary of Product Characteristics for ritonavir must be consulted before initiation of therapy with Atazanavir Mylan and ritonavir.
Icelandic: Áður en meðferð með Atazanavir Mylan og rítínóvíri hefst þarf að athuga Samantekt á eiginleikum rítónavírs.
English: No drug interaction study has been performed for the co-administration of atazanavir with benzodiazepines.
Icelandic: Engar rannsóknir á milliverkunum vegna samtímis notkunar atazanavírs og benzódíazepína hafa verið gerðar.
English: PULMONARY ARTERIAL HYPERTENSION PDE5 Inhibitors
Icelandic: PDE5 HEMLAR
English: The mechanism of diltiazem/atazanavir interaction is CYP3A4 inhibition.
Icelandic: Verkunarháttur milliverkana diltiazem/atazanavír er CYP3A4 hömlun.
English: No dose adjustment is needed for atazanavir.
Icelandic: Ekki er mælt með Atazanavir
English: No significant effect on didanosine and stavudine concentrations was observed.
Icelandic: Engin marktæk áhrif á þéttni dídanósíns og stavúdíns komu í ljós.
English: Children receiving Atazanavir Mylan may require their heart to be monitored.
Icelandic: Nauðsynlegt getur verið að fylgjast með hjartastarfsemi hjá börnum sem fá Atazanavir Mylan.
English: Atazanavir Mylan 200 mg hard capsules - The active substance is atazanavir.
Icelandic: Mylan 200 mg hörð hylki Virka innihaldsefnið er atazanavír.
English: Tenofovir disoproxil fumarate 300 mg once daily
Icelandic: Tenófóvír dísóproxílfúmarat 300 mg einu sinni á dag
English: Co-administration with atazanavir has the potential to increase or decrease warfarin concentrations.
Icelandic: Við samhliða gjöf atazanavírs getur hugsanlega orðið hækkun eða lækkun í þéttni warfaríns.
English: Atazanavir Cmax ↔9% (↓5% ↑26%)
Icelandic: Atazanavír Cmax ↔9% (↓5%
English: Co-administration of salmeterol with atazanavir is not recommended (see section 4.4).
Icelandic: Ekki má gefa alfuzosín ásamt atazanavíri (sjá kafla 4.3).
English: (atazanavir 300 mg and ritonavir 100 mg once daily)
Icelandic: (atazanavír 300 mg og rítónavír 100 mg einu sinni á dag)
English: Each hard capsule contains 300 mg of atazanavir (as sulphate).
Icelandic: Hvert hart hylki inniheldur 300 mg af atazanavíri (sem súlfat).
English: ANTIBIOTICS Clarithromycin 500 mg twice daily
Icelandic: Claritrómýcin 500 mg tvisvar á dag (atazanavír 400 mg einu sinni á dag)
English: Table 4.
Icelandic: Tafla 6:
English: Atazanavir Mylan dose once daily (mg)
Icelandic: Mylan skammtur einu sinni á sólarhring (mg)
English: Efavirenz 600 mg once daily
Icelandic: Efavírenz 600 mg einu sinni á dag
English: BOTTLE LABEL FOR 300 MG HARD CAPSULES
Icelandic: MERKING Á ÞYNNUÖSKJU FYRIR 300 MG HÖRÐ HYLKI
English: Indinavir is associated with indirect unconjugated hyperbilirubinaemia due to inhibition of UGT.
Icelandic: Indínavír tengist óbeint bilirúbínhækkun í blóði (óbundið bilirúbín) vegna bælingar á UGT.
English: The length of combination antiretroviral therapy, corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index, among others, may be some of the many risk factors for developing this disease.
Icelandic: Nokkrir af mörgum áhættuþáttum, fyrir myndun þessa sjúkdóms, geta verið lengd samsettrar andretróveirumeðferðar, notkun barkstera, áfengisneysla, öflug ónæmisbæling og hár líkamsþyngdarstuðull (BMI).
English: If signs or symptoms of nephrolithiasis occur, temporary interruption or discontinuation of treatment may be considered.
Icelandic: Ef einkenni nýrnasteinakvilla koma fram þarf að hugleiða tímabundið hlé á meðferðinni eða hætta henni alveg.
English: Each hard capsule contains 200 mg of atazanavir (as sulphate).
Icelandic: Hvert hart hylki inniheldur 200 mg af atazanavíri (sem súlfat).
English: It is not known whether Atazanavir Mylan with ritonavir administered to the mother during pregnancy will exacerbate physiological hyperbilirubinaemia and lead to kernicterus in neonates and infants.
Icelandic: Þegar Atazanavir Mylan ásamt rítónavíri er gefið konum á meðgöngu er ekki vitað hvort það hækki bilirúbín í blóði og valdi gulufárstaugakvilla hjá nýburum og ungbörnum.
English: During postpartum
Icelandic: eftir omeprazol
English: (atazanavir 400 mg once daily with ritonavir 100 mg once daily)
Icelandic: (atazanavír 400 mg einu sinni á dag ásamt rítónavíri 100 mg einu sinni á dag)
English: Cholelithiasis
Icelandic: Gallsteinar
English: Close monitoring of patient's virologic response should be exercised.
Icelandic: Fylgjast skal náið með veirusvörun sjúklings.
English: For treatment-naive paediatric patients, the mean baseline CD4 cell count was 344 cells/mm
Icelandic: Hjá sjúklingum sem höfðu ekki fengið meðferð með andretróveirulyfjum áður var meðalupphafsgildi CD4 344 frumur/mm3 (á bilinu 2-800 frumur/mm3) og meðalupphafsgildi HIV 1
English: The mechanism of interaction between atazanavir and ritonavir is CYP3A4 inhibition.
Icelandic: Verkunarháttur milliverkana atazanavírs og rítónavírs er CYP3A4 hömlun.
English: Atazanavir Mylan 300 mg hard capsules
Icelandic: Mylan 300 mg hörð hylki
English: The mechanism of this interaction is CYP3A4 inhibition.
Icelandic: Verkunarháttur þessarar milliverkunar er CYP3A4 hömlun.
English: Unchanged drug accounted for approximately 20% and 7% of the administered dose in the faeces and urine, respectively.
Icelandic: U.þ.b. 20% af lyfinu á óbreyttu formi finnst í hægðum og 7% í þvagi.
English: De novo substitutions in treatment experienced patients failing therapy with atazanavir +
Icelandic: Fullorðnir sjúklingar sem hafa ekki fengið meðferð með andretróveirulyfjum
English: The mechanism of interaction is CYP3A4 inhibition.
Icelandic: Verkunarháttur milliverkana er CYP3A4 hömlun.
English: TM
Icelandic: Τηλ:
English: Atazanavir Mylan 150 mg hard capsules
Icelandic: Mylan 150 mg hörð hylki
English: (range: 2 to 800 cells/ mm 3) and mean baseline plasma HIV 1 RNA was 4.67 log10 copies/ml (range: 3.70 to 5.00 log10 copies/ml).
Icelandic: RNA í plasma 4,67 log10 eintök/ml (á bilinu:3,70-5,00 log10 eintök/ml).
English: Concentrations of atazanavir (when given with ritonavir) were not significantly affected.
Icelandic: Ekki marktæk áhrif á þéttni atazanavírs (þegar lyfið er gefið ásamt rítónavíri).
English: Voriconazole 50 mg twice daily (atazanavir 300 mg/ritonavir 100 mg once daily)
Icelandic: Lamivúdín 150 mg tvisvar á dag + zídóvúdín 300 mg tvisvar á dag (atazanavír 400 mg einu sinni á dag)
English: • myopathy (aching muscles, muscle tenderness of weakness, not caused by exercise)
Icelandic: QTc lenging (óreglulegur hjartsláttur) óeðlilegt göngulag bjúgur lifrar- og miltisstækkun vöðvakvilli (einkenni frá vöðvum sem ekki eru af völdum líkamsræktar) verkur í nýrum
English: Store in the originalpackage in order to protect from moisture.
Icelandic: Geymið ekki við hærri hita en 25°C. Geymið í upprunalegum umbúðum til varnar gegn raka.
English: Atazanavir is metabolised in the liver through CYP3A4.
Icelandic: Atazanavír umbrotnar í lifur fyrir tilstuðlan CYP3A4.
English: 30 hard capsules 60 hard capsules.
Icelandic: LYFJAFORM OG INNIHALD 30 hörð hylki.
English: The mechanism of this decrease is unknown.
Icelandic: Verkunarháttur þessarar lækkunar er ekki þekktur.
English: The mechanism of amiodarone or systemic lidocaine/atazanavir interaction is CYP3A inhibition.
Icelandic: Verkunarháttur milliverkana amiódarons eða lídókains (til almennrar notkunar) og atazanavírs er vegna CYP3A hömlunar.
English: Each capsule contains 150 mg atazanavir (as sulphate)
Icelandic: Hvert hylki inniheldur 150 mg af atazanavíri (sem súlfat).
English: Systemic corticosteroid effects including Cushing's syndrome and adrenal suppression have been reported in patients receiving ritonavir and inhaled or intranasally administered fluticasone propionate; this could also occur with other corticosteroids metabolised via the P450 3A pathway, e.g., budesonide.
Icelandic: Greint hefur verið frá almennum barksteraáhrifum m.a. Cushings heilkenni og bælandi áhrifum á nýrnahettur hjá sjúklingum sem fengu rítónavír og flútíkasón própíónat með innöndun eða í nef.
English: Atazanavir Cmax ↓23% (↓36% ↓8%)
Icelandic: Atazanavír Cmax ↓23% (↓33% ↓12%)
English: uncommon: nephrolithiasis a, haematuria, proteinuria, pollakiuria, interstitial nephritis, chronic kidney disease a;
Icelandic: (DRESS heilkenni)a,b, ofnæmisbjúgura, ofsakláði, hárlos, kláði mjög sjaldgæfar:
English: Rifabutin 150 mg twice weekly
Icelandic: Vorikónazól 50 mg tvisvar á dag
English: This leaflet was last revised in
Icelandic: Tíðni aukaverkana hér að neðan er skilgreind á eftirfarandi hátt:
English: Number of patients with paired genotypes classified as virological failures (HIV RNA ≥ 400 copies/ml).
Icelandic: CD4 Meðalbreyting frá upphafsgildi frumur/mm3 af upphafsgildi HIV RNA <100.000 eintök/ml
English: The co-administration of stavudine with atazanavir is not expected to significantly alter the exposure of stavudine.
Icelandic: Þegar stavúdín er gefið samhliða atazanavíri er ekki gert ráð fyrir marktækri breytingu á útsetningu fyrir stavúdíni.
English: Carbamazepine should be used with caution in combination with atazanavir.
Icelandic: Gæta skal varúðar við notkun karbamazepíns samhliða atazanavíri.
English: Atazanavir Mylan with ritonavir is contraindicated in patients with moderate hepatic insufficiency (see sections 4.2, 4.4 and 5.2).
Icelandic: Mylan ásamt rítónavíri má ekki nota hjá sjúklingum með í meðallagi alvarlega lifrarbilun (sjá kafla 4.2, 4.4 og 5.2).
English: Human experience of acute overdose with atazanavir is limited.
Icelandic: Takmörkuð reynsla er af bráðri ofskömmtun atazanavírs hjá mönnum.
English: Atazanavir may affect how well your kidneys work.
Icelandic: Atazanavir getur haft áhrif á starfsemi nýrnanna.
English: 200 mg capsules
Icelandic: 200 mg hörð hylki
English: In clinical trials of antiretroviral treatment naive patients treated with boosted atazanavir, the I50L substitution did not emerge in any patient without baseline PI substitutions.
Icelandic: örvað atazanavír kom I50L útskipting ekki fram hjá neinum sjúklingi án útskiptingar fyrir próteasahemla í upphafi.
English: Weight and metabolic parameters
Icelandic: LYF SEM HAFA ÁHRIF Á MÝCOBAKTERÍUR
English: Intent-to-treat analysis, with missing values considered as failures.
Icelandic: a Greining á þeim sem til stóð að meðhöndla (intent-to-treat analysis), þar sem litið var á gildi sem vantaði sem meðferðarbrest.
English: Lactose
Icelandic: Umbrot
English: Each capsule contains 300 mg or atazanavir (as sulphate).
Icelandic: Hvert hylki inniheldur 300 mg af atazanavíri (sem súlfat).
English: The capsules should be swallowed whole.
Icelandic: Blóðfituröskun skal meðhöndla eins og klínískt á við.
English: Excipients
Icelandic: Pravastatín
English: (atazanavir 300 mg once daily with ritonavir 100 mg once daily)
Icelandic: (atazanavír 300 mg einu sinni á dag með rítónavír 100 mg einu sinni á dag)
English: See section 4.
Icelandic: Tafla 7:
English: Atazanavir Mylan with ritonavir must not be used in patients with moderate to severe hepatic impairment (see sections 4.3, 4.4, and
Icelandic: Sjúklingar með í meðallagi alvarlega skerta/alvarlega skerta lifrarstarfsemi eiga ekki að nota Atazanavir Mylan ásamt rítónavíri (sjá kafla 4.3, 4.4 og 5.2).
English: Each capsule contains 200 mg atazanavir (as sulphate)
Icelandic: Hvert hylki inniheldur 200 mg af atazanavíri (sem súlfat).
English: • if you have moderate to severe liver problems.
Icelandic: ef þú ert með meðalalvarlegan/alvarlegan lifrarsjúkdóm.
English: Elbasvir Cmax: ↑315% (↑246%
Icelandic: ↑315% (↑246% Elbasvir Cmin:
English: Grazoprevir concentrations were greatly increased when co-administered with atazanavir/ritonavir.
Icelandic: Þéttni grazoprevirs jókst stórlega við samhliða gjöf atazanavirs/ritonavirs.
English: Musculoskeletal and connective tissue disorders:
Icelandic: Sjúklingar sem fá tenófóvír dísóproxílfúmarat:
English: 300 mg capsules
Icelandic: 300 mg hörð hylki
English: PHARMACOLOGICAL PROPERTIES
Icelandic: LYFJAFRÆÐILEGAR UPPLÝSINGAR
English: Atazanavir is metabolised and eliminated primarily by the liver.
Icelandic: Umbrot og brotthvarf atazanavírs fer aðallega fram í lifur.
English: C-atazanavir, 79% and 13% of the total radioactivity was recovered in the faeces and urine, respectively.
Icelandic: Eftir einn 400 mg skammt af 14C-atazanavír kom 79% af heildargeislavirkni fram í hægðum og 13% í þvagi.
English: Each hard capsule contains 150 mg atazanavir (as sulphate).
Icelandic: Hvert hart hylki inniheldur 150 mg atazanavír (sem súlfat).
English: MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS
Icelandic: LÁGMARKS UPPLÝSINGAR SEM SKULU KOMA FRAM Á ÞYNNUM EÐA STRIMLUM 1. HEITI LYFS
English: Each hard capsule contains 200 mg atazanavir (as sulphate).
Icelandic: Hvert hart hylki inniheldur 200 mg atazanavír (sem súlfat).
English: EU/1/16/1091/003
Icelandic: 12. MARKAÐSLEYFISNÚMER EU/1/16/1091/003
English: Buprenorphine Cmin ↑69%
Icelandic: Etinýlöstradiól Cmin ↑ 91%
English: The concomitant use of quinidine is contraindicated (see section 4.3).
Icelandic: Kínidín á ekki að nota samhliða (sjá kafla 4.3).
English: common: headache; uncommon: peripheral neuropathy, syncope, amnesia, dizziness, somnolence, dysgeusia
Icelandic: algengar: höfuðverkur sjaldgæfar: úttaugakvilli, yfirlið, minnisleysi, sundl, svefnhöfgi, brenglað bragðskyn
English: Atazanavir Mylan 150 mg hard capsules Atazanavir Mylan 200 mg hard capsules Atazanavir Mylan 300 mg hard capsules atazanavir
Icelandic: Mylan 300 mg hörð hylki atazanavír VIRK(T) EFNI Hvert hart hylki inniheldur 300 mg af atazanavíri (sem súlfat).
English: In some cases, nephrolithiasis has been associated with acute renal failure or renal insufficiency.
Icelandic: Í nokkrum tilvikum hefur nýrnasteinakvilli tengst bráðri nýrnabilun eða skertri nýrnastarfsemi.
English: SEDATIVES Benzodiazepines Midazolam
Icelandic: JURTALYF Jóhannesarjurt