FrancophonIA/ELRC3.0 huggingface dataset:
English: The study had two primary endpoints: all cause mortality (time to death) and composite mortality and heart failure morbidity (time to first morbid event) defined as death, sudden death with resuscitation, hospitalisation for heart failure, or administration of intravenous inotropic or vasodilator agents for four hours or more without hospitalisation.
Lithuanian: Tyrimas buvo vertinamas atsižvelgiant du pirminius vertinamosios baigties kriterijus: mirtingum d l bet kokios priežasties (laik , per kur vyko mirtis) ir kombinuot mirtingum bei mirtingum d l širdies nepakankamumo sukeltos patologijos (laik , per kur pasireišk pirmasis patologinis reiškinys), tai apibr žiama kaip mirtis, staigi mirtis, kurios metu ligonis atgaivintas, hospitalizacija d l širdies nepakankamumo arba ne ligonin je pacientui keturias valandas ar ilgiau ven infuzuota širdies inotropin funkcij stiprinan i arba kraujagysles ple ian i medikament .
English: A somewhat higher systemic exposure to valsartan was observed in some elderly subjects than in young subjects; however, this has not been shown to have any clinical significance.
Lithuanian: Pasteb ta, kad kai kuri pagyvenusi žmoni organizme valsartano ekspozicija buvo šiek tiek didesn nei jaun , ta iau klinikai tai nebuvo reikšminga.
English: Weight
Lithuanian: Stiprumas
English: In general, it is recommended that patients achieve a dose level of 80 mg twice daily by two weeks after treatment initiation and that the target maximum dose, 160 mg twice daily, be achieved by three months, based on the patient's tolerability.
Lithuanian: Paprastai pacientams rekomenduojama 80 mg doz pasiekti per dvi savaites nuo gydymo pradžios, o tikslin didžiausi doz - 160 mg du kartus per par -per tris m nesius, atsižvelgiant tai, kaip pacientas j toleruoja.
English: The apparent clearance of valsartan following oral administration is approximately 4.5 l/h.
Lithuanian: Išgerto valsartano klirensas yra maždaug 4,5 l /val.
English: • [Storage conditions statements - To be completed nationally]
Lithuanian: • [Laikymo s lygos - pildyti savo šalies kalba]
English: This dose is 6 times the maximum recommended human dose on a mg/m2 basis (calculations assume an oral dose of 320 mg/day and a 60-kg patient).
Lithuanian: Tokia doz yra 6 kartus didesn už didžiausi rekomenduojam doz žmogui, perskai iuojant mg/m2 paviršiaus ploto (skai iuojant laikyta, kad geriamoji paros doz yra 320 mg, o pacientas sveria 60 kg).
English: The recommended starting dose of Diovan is 80 mg once daily.
Lithuanian: Rekomenduojama pradin Diovan doz yra 80 mg vien kart per par .
English: In patients who weigh 35 kg or more the usual starting dose is 80 mg of valsartan once daily.
Lithuanian: Jei pacientas sveria 35 kg ar daugiau, prasta vien kart per par vartojama pradin valsartano doz yra 80 mg.
English: After an initial dose of 20 mg twice daily, valsartan should be titrated to 40 mg, 80 mg, and 160 mg twice daily over the next few weeks.
Lithuanian: Po pradin s, du kartus per par vartojamos 20 doz s, per kelias tolesnes savaites valsartano doz reikia pritaikyti iki 4080 ir 160 mg du kartus per par .
English: HOW TO TAKE DIOVAN
Lithuanian: KAIP LAIKYTI DIOVAN
English: Diovan is contraindicated in patients with severe hepatic impairment, biliary cirrhosis and in patients with cholestasis (see sections 4.3, 4.4 and 5.2).
Lithuanian: Diovan negalima skirti pacientams, kuriems yra sunkus kepen funkcijos sutrikimas, biliarin ciroz ar cholestaz (žr. 4.3, 4.4 ir 5.2 skyrius).
English: In some patients whose blood pressure is not adequately controlled, the dose can be increased to 160 mg and to a maximum of 320 mg. Diovan may also be administered with other antihypertensive agents.
Lithuanian: Kai kuriems pacientams, kuri kraujosp dis sureguliuojamas nepakankamai, doz galima didinti iki 160 mg ir iki didžiausios 320 mg doz s.
English: No dose adjustment is required for adult patients with a creatinine clearance >10 ml/min (see sections 4.4 and 5.2).
Lithuanian: Suaugusiesiems pacientams, kuri kreatinino klirensas > 10 ml/min, doz s koreguoti nereikia (žr. 4.4 ir 5.2 skyrius).
English: There was no difference in all-cause mortality, cardiovascular mortality or morbidity when beta blockers were administered together with the combination of valsartan + captopril, valsartan alone, or captopril alone.
Lithuanian: Mirtingumas d l bet kokios priežasties, d l širdies ir kraujagysli lig ar sergamumas po to, kai buvo paskirti beta adrenoblokatoriai kartu su valsartanu ir kaptopriliu, vien tiktai valsartanas arba vien tiktai kaptoprilis, nebuvo skirtingas.
English: Patients treated with valsartan had a better quality of life as demonstrated by change in the Minnesota Living with Heart Failure Quality of Life score from baseline at endpoint than placebo.
Lithuanian: Valsartanu gydyt pacient gyvenimo kokyb , lyginant pradži ir pabaig , buvo geresn nei t , kuriems buvo skiriamas placebas, tai paaišk jo, vertinus poky ius pagal Minesotos gyvenimo kokyb s skal , pagal kuri vertinamas gyvenimas esant širdies nepakankamumui.
English: Food decreases exposure (as measured by AUC) to valsartan by about 40% and peak plasma concentration (Cmax) by about 50%, although from about 8 h post dosing plasma valsartan concentrations are similar for the fed and fasted groups.
Lithuanian: Valsartano išg rus valgio metu, plotas po koncentracijos kreive (AUC) sumaž ja 40%, o didžiausia koncentracija plazmoje (Cmax) - apie 50 %, ta iau pra jus maždaug 8 val.
English: Rixil 320 mg 320 mg
Lithuanian: Rixil 320 mg
English: Rua do Centro Empresarial, Edificio 8 Quinta da Beloura
Lithuanian: Quinta da Beloura
English: Rixil 40 mg 40 mg
Lithuanian: Rixil 40 mg
English: Provas 320 mg 320 mg
Lithuanian: Provas 320 mg
English: Valsartan was also effective in prolonging the time to and reducing cardiovascular mortality, hospitalisation for heart failure, recurrent myocardial infarction, resuscitated cardiac arrest, and non-fatal stroke (secondary composite endpoint).
Lithuanian: Valsartanas buvo veiksmingas ir ilginant laik iki mirties d l širdies ir kraujagysli lig , mažinant kardiovaskulin mirštamum , b tinum ligon guldyti ligonin d l širdies funkcijos nepakankamumo, miokardo infarkto pasikartojimo, atgaivinimo po širdies sustojimo bei nemirtino smegen insulto (antrinis sud tinis vertinamosios baigties kriterijus).
English: One film-coated tablet contains 320 mg of valsartan.
Lithuanian: Vienoje pl vele dengtoje tablet je yra 320 mg valsartano.
English: Novartis Farmacéutica, S.A. Gran Via de les Corts Catalanes, 764
Lithuanian: Gran Via de les Corts Catalanes,
English: Hypertension Treatment of hypertension in children and adolescents 6 to 18 years of age.
Lithuanian: Arterin hipertenzija Hipertenzijos gydymas 6-18 met vaikams ir paaugliams.
English: When angiotensin II antagonists are administered simultaneously with NSAIDs, attenuation of the antihypertensive effect may occur.
Lithuanian: Skiriant angiotenzino II antagonistus ir NVNU vienu metu, gali silpniau pasireikšti kraujosp d mažinantis poveikis.
English: (5-10 mg/od), in 332 type 2 diabetic patients (mean age: 58 years; 265 men) with microalbuminuria (valsartan: 58 µg/min; amlodipine: 55.4 µg/min), normal or high blood pressure and with preserved renal function (blood creatinine <120 µmol/l).
Lithuanian: (amžiaus vidurkis 58 metai; 265 vyrai), kuriems pasireišk mikroalbuminurija (valsartanas58 µg/min; amlodipinas - 55,4 µg/min), buvo normalus arba aukštas kraujosp dis ir išsaugota inkst funkcija (kreatininas kraujyje <120 µmol/l).
English: Provas 160 mg 160 mg
Lithuanian: Provas 160 mg
English: Tareg 40 mg 40 mg
Lithuanian: Tareg 40 mg
English: The Diovan Reduction of Proteinuria (DROP) study further examined the efficacy of valsartan in reducing UAE in 391 hypertensive patients (BP=150/88 mmHg) with type 2 diabetes, albuminuria (mean=102 µg/min; 20-700 µg/min) and preserved renal function (mean serum creatinine = 80 µmol/l).
Lithuanian: Diovan Reduction of Proteinuria, DROP) buvo toliau tiriamas valsartano veiksmingumas, mažinant AIŠ 391 hipertenzija sergantiems pacientams (AKS=150/88 mmHg), kurie papildomai sirgo II tipo cukriniu diabetu, jiems pasireišk albuminurija (vidurkis=102 µg/min; 20-700 µg/min) ir buvo išsaugota inkst funkcija (vidutin kreatinino koncentracija serume = 80 µmol/l).
English: Rixil 160 mg 160 mg
Lithuanian: Rixil 160 mg
English: These doses in rats (600 mg/kg/day) are approximately 18 times the maximum recommended human dose on a mg/m2 basis (calculations assume an oral dose of 320 mg/day and a 60-kg patient).
Lithuanian: Ši doz žiurk ms (600 mg/kg per par ) yra maždaug 18 kart didesn už rekomenduojam doz žmogui, jei remiamasi mg/m2 matavimu (skai iuojant 60 kg svorio pacientei, gaut si 320 mg paros doz ).
English: Valsartan may be administered with other heart failure therapies.
Lithuanian: Valsartan galima skirti kartu su kitais vaistais, skirtais širdies nepakankamumui gydyti.
English: In patients with heart failure, the triple combination of an ACE inhibitor, a beta blocker and Diovan has not shown any clinical benefit (see section 5.1).
Lithuanian: Širdies nepakankamumo atvejais pacientams skiriant trij vaist - AKF inhibitoriaus, beta adrenoblokatoriaus ir Diovan - derin klinikin s naudos nebuvo (žr.
English: Diovane 40 mg 40 mg
Lithuanian: Diovane 40 mg
English: Rixil 80 mg 80 mg
Lithuanian: Rixil 80 mg
English: Cordinate 40 mg 40 mg
Lithuanian: Cordinate 40 mg
English: Tareg 80 mg 80 mg
Lithuanian: Tareg 80 mg
English: The VALsartan In Acute myocardial iNfarcTion trial (VALIANT) was a randomised, controlled, multinational, double-blind study in 14,703 patients with acute myocardial infarction and signs, symptoms or radiological evidence of congestive heart failure and/or evidence of left ventricular systolic dysfunction (manifested as an ejection fraction 40% by radionuclide ventriculography or 35% by echocardiography or ventricular contrast angiography).
Lithuanian: Tyrime dalyvavo 14 703 pacientai po maus miokardo infarkto, kuriems buvo radiologiniu tyrimu patvirtinto stazinio širdies nepakankamumo simptom ir požymi ir (arba) kairiojo širdies skilvelio sistolin s funkcijos sutrikimas: išmetimo frakcija, nustatyta radionuklidine ventrikulografija, buvo ≤ 40% , nustatyta echokardiografija ar kontrastin s angiografijos b du − ≤ 35 %).
English: In the overall Val-HeFT population, valsartan treated patients showed significant improvement in NYHA class, and heart failure signs and symptoms, including dyspnoea, fatigue, oedema and rales compared to placebo.
Lithuanian: Bendroje val-HeFT populiacijoje valsartanu gydyt pacient b kl , lyginant su placebo grupe, reikšmingai pager jo, vertinant NYHA klas s kriterijus, širdies nepakankamumo požymius ir simptomus: dusul , nuovarg , edem ir karkalus.
English: In patients whose renal function may depend on the activity of the renin-angiotensin system (e.g patients with severe congestive heart failure), treatment with angiotensin converting enzyme inhibitors has been associated with oliguria and/or progressive azotaemia and in rare cases with acute renal failure and/or death.
Lithuanian: Pacient , kuri inkst funkcija gali priklausyti nuo renino-angiotenzino sistemos aktyvumo (pvz., pacient , sergan i sunkiu staziniu širdies nepakankamumu), gydymas angiotenzin konvertuojan io fermento inhibitoriais buvo susij s su oligurija ir (arba) progresuojan ia azotemija, retais atvejais − su miniu inkst nepakankamumu ir (arba) mirtimi.
English: The average time to peak concentration and elimination half-life of valsartan in heart failure patients are similar to that observed in healthy volunteers.
Lithuanian: Širdies nepakankamumu sergan i pacient organizme vidutinis laikas, per kur valsartano koncentracija kraujyje tampa didžiausia, ir pusin s eliminacijos laikas yra tokie patys kaip sveik savanori .
English: Cordinate 80 mg 80 mg
Lithuanian: Cordinate 80 mg
English: In clinically stable patients, therapy may be initiated as early as 12 hours after a myocardial infarction.
Lithuanian: Pacientus, kuri klinikin b kl stabili, galima prad ti gydyti ne anks iau kaip pra jus 12 valand nuo miokardo infarkto.
English: Dalzad 80 mg 80 mg
Lithuanian: Dalzad 80 mg
English: Diovane 80 mg 80 mg
Lithuanian: Diovane 80 mg
English: Your doctor will increase this dose gradually over several weeks to a maximum of 160 mg twice daily.
Lithuanian: Gydytojas ši doz didins palaipsniui kelet savai i iki didžiausios 160 mg doz s du kartus per par .
English: Cordinate 320 mg 320 mg
Lithuanian: Cordinate 320 mg
English: At 24 weeks, UAE was reduced (p <0.001) by 42% (-24.2 µg/min; 95% CI: -40.4 to -19.1) with valsartan and approximately 3% (-1.7 µg/min; 95% CI: -5.6 to 14.9) with amlodipine despite similar rates of blood pressure reduction in both groups.
Lithuanian: Per 24 savaites AIŠ sumaž jo (p < 0,001) 42 % (-24,2 µg/min; 95 % PI: nuo -40,4 iki -19,1) skiriant valsartan ir apie 3 % (-1,7 µg/min; 95 % PI: nuo -5,6 iki 14,9) skiriant amlodipin , nepaisant panašaus kraujosp džio rodikli sumaž jimo abejose grup se.
English: Heart failure symptoms include shortness of breath, and swelling of the feet and legs due to fluid build-up.
Lithuanian: Širdies nepakankamumo simptomai yra dusulys, p d ir koj patinimas d l skys i susikaupimo.
English: Cordinate 160 mg 160 mg
Lithuanian: Cordinate 160 mg
English: At 24 weeks, UAE was reduced (p<0.001) by 42% (-24.2 µg/min; 95% CI: -40.4 to -19.1) with valsartan and approximately 3% (-1.7 µg/min; 95% CI: -5.6 to 14.9) with amlodipine despite similar rates of blood pressure reduction in both groups.
Lithuanian: Per 24 savaites AIŠ sumaž jo (p < 0,001) 42 % (24,2 µg/min; 95 % PI: nuo -40,4 iki -19,1) skiriant valsartan ir apie 3 % (-1,7 µg/min; 95 % PI: nuo5,6 iki 14,9) skiriant amlodipin , nepaisant panašaus kraujosp džio rodikli sumaž jimo abejose grup se.
English: Diovane 160 mg 160 mg
Lithuanian: Diovane 160 mg
English: Hyperkalaemia was more frequently observed in children and adolescents aged 6 to 18 years with underlying chronic kidney disease.
Lithuanian: 6-18 met vaikams ir paaugliams, sirgusiems l tine inkst liga, dažniau pasireikšdavo hiperkaliemija.
English: • if you are being treated for heart failure, a triple combination with ACE inhibitors and beta blockers (medications to treat heart failure) is not recommended.
Lithuanian: • jeigu Jums skiriamas gydymas d l širdies nepakankamumo, nerekomenduojama tuo pa iu metu vartoti trij r ši vaistus - AKF inhibitorius ir beta adrenoblokatorius (vaistus, naudojamus širdies nepakankamumui gydyti);
English: Tareg 320 mg 320 mg
Lithuanian: Tareg 320 mg
English: However, the triple combination of an ACE inhibitor, a beta blocker and valsartan is not recommended (see sections 4.4 and 5.1).
Lithuanian: Ta iau nerekomenduojama skirti trij vaist - AKF inhibitoriaus, beta adrenoblokatoriaus ir valsartanoderinio (žr. 4.4 ir 5.1 skyrius).
English: Tareg 160 mg 160 mg
Lithuanian: Tareg 160 mg
English: Diovane 320 mg 320 mg
Lithuanian: Diovane 320 mg
English: Diovan is used when a group of medicines called Angiotensin Converting Enzyme (ACE) inhibitors (a medication to treat heart failure) cannot be used or it may be used in addition to ACE inhibitors when beta blockers (another medication to treat heart failure) cannot be used.
Lithuanian: Diovan naudojamas, kai negalima vartoti grup s vaist , vadinam angiotenzin konvertuojan io fermento (AKF) inhibitoriais (vaist , skirt širdies nepakankamumui gydyti) arba j galima naudoti kartu su AKF inhibitoriais, kai negalima vartoti beta adrenoblokatori (kit vaist , skirt širdies nepakankamumui gydyti).
English: Dalzad 160 mg 160 mg
Lithuanian: Dalzad 160 mg
English: The MARVAL (Micro Albuminuria Reduction with Valsartan) study assessed the reduction in urinary albumin excretion (UAE) with valsartan (80-160 mg/od) versus amlodipine (5-10 mg/od), in 332 type 2 diabetic patients (mean age: 58 years; 265 men) with microalbuminuria (valsartan: 58 µg/min; amlodipine: 55.4 µg/min), normal or high blood pressure and with preserved renal function (blood creatinine <120 µmol/l).
Lithuanian: Micro Albuminuria Reduction with valsartan, „mikroalbuminurijos sumažinimo skiriant valsartan “) tyrimo metu buvo vertinamas albumino išsiskyrimas su šlapimu (AIŠ), skiriant valsartan (80-160 mg, skiriant vien kart per par ) arba amlodipin (5-10 mg, skiriant vien kart per par ) 332 antrojo tipo cukriniu diabetu sergantiems pacientams (amžiaus vidurkis 58 metai; 265 vyrai), kuriems pasireišk mikroalbuminurija (valsartanas - 58 µg/min; amlodipinas55,4 µg/min), buvo normalus arba aukštas kraujosp dis ir išsaugota inkst funkcija (kreatininas kraujyje < 120 µmol/l).
English: • if you are being treated after a heart attack, a combination with ACE inhibitors (a medication to treat heart attack) is not recommended.
Lithuanian: • jeigu Jums skiriamas gydymas po miokardo infarkto, nerekomenduojama tuo pa iu metu vartoti AKF inhibitori (vaist , naudojam miokardo infarktui gydyti);
English: Treatment of essential hypertension in adults, and hypertension in children and adolescents 6 to 18 years of age.
Lithuanian: Pirmin s arterin s hipertenzijos gydymas suaugusiesiems žmon ms bei hipertenzijos gydymas 6-18 met vaikams ir paaugliams.
English: Dalzad 320 mg 320 mg
Lithuanian: Dalzad 320 mg
English: Diovan 160 mg film-coated tablets can be used for three different conditions:
Lithuanian: Diovan 160 mg pl vele dengtos tablet s gali b ti naudojamos trim skirtingais atvejais:
English: Combining valsartan with captopril did not add further benefit over captopril alone.
Lithuanian: Kartu su kaptopriliu prad jus vartoti valsartan , didesn s naudos, negu gydant vien kaptopriliu, negauta.
English: Diovan 40 mg film-coated tablets can be used for three different conditions:
Lithuanian: Diovan 40 mg pl vele dengtos tablet s gali b ti naudojamos trim skirtingais atvejais:
English: Diovan 80 mg film-coated tablets can be used for three different conditions:
Lithuanian: Diovan 80 mg pl vele dengtos tablet s gali b ti naudojamos trim skirtingais atvejais:
English: Patients were randomised within 12 hours to 10 days after the onset of myocardial infarction symptoms to valsartan, captopril, or the combination of both.
Lithuanian: - 10 dien nuo miokardo infarkto simptom atsiradimo pradžios, pacientai atsitiktini im i b du buvo suskirstyti tris grupes: valsartano, kaptoprilio, valsartano ir kaptoprilio.
English: Evaluation of post-myocardial infarction patients should always include assessment of renal function.
Lithuanian: Vertinant pacient b kl po miokardo infarkto, taip pat visada reikia vertinti ir inkst funkcij .
English: In some cases your doctor may prescribe higher doses (e.g. 160 mg or 320 mg).
Lithuanian: Tam tikrais atvejais gydytojas gali skirti didesn doz (ji gali b ti padidinta iki 160 mg ir maksimalios 320 mg doz s).
English: One film-coated tablet contains 40 mg of valsartan.
Lithuanian: Vienoje pl vele dengtoje tablet je yra 40 mg valsartano.
English: • allergic reactions with rash, itching and hives; symptoms of fever, swollen joints and joint pain,
Lithuanian: • alergin reakcija, pasireiškianti išb rimu, niežuliu ir dilg line; galimi tokie simptomai kaip karš iavimas, s nari patinimas ir skausmas, raumen skausmas, limfmazgi patinimas ir (arba) simptomai, panaš s gripo (serumin s ligos požymiai);
English: Doses higher than those listed have not been studied and are therefore not recommended.
Lithuanian: Didesn s nei nurodytos doz s netirtos, tod l j vartoti nerekomenduojama.
English: One film-coated tablet contains 80 mg of valsartan.
Lithuanian: Vienoje pl vele dengtoje tablet je yra 80 mg valsartano.
English: Adult patients after a recent heart attack: After a heart attack the treatment is generally started as early as after 12 hours, usually at a low dose of 20 mg twice daily.
Lithuanian: Po miokardo infarkto gydymas paprastai pradedamas per 12 valand , skiriama prasta 20 mg doz du kartus per par .
English: You obtain the 20 mg dose by dividing the 40 mg tablet.
Lithuanian: Pradin doz gaunama padalinus 40 mg tablet .
English: The MARVAL (Micro Albuminuria Reduction with Valsartan) study assessed the reduction in urinary albumin excretion (UAE) with valsartan (80-160 mg/od) versus amlodipine
Lithuanian: Micro Albuminuria Reduction with valsartan, „mikroalbuminurijos sumažinimo skiriant valsartan “) tyrimo metu buvo vertinamas albumino išsiskyrimas su šlapimu (AIŠ), skiriant valsartan (80-160 mg vien kart per par) arba amlodipin (5-10 mg vien kart per par) 332 antrojo tipo diabetu sergantiems pacientams
English: One film-coated tablet contains 160 mg of valsartan.
Lithuanian: Vienoje pl vele dengtoje tablet je yra 160 mg valsartano.
English: Valsartan was as effective as captopril in reducing all-cause mortality after myocardial infarction.
Lithuanian: Mirtingum po miokardo infarkto d l bet kokios priežasties valsartanas mažinto tiek pat veiksmingai, kaip kaptoprilis.
English: All-cause mortality was similar in the valsartan (19.9%), captopril (19.5%), and valsartan + captopril (19.3%) groups.
Lithuanian: Valsartanu (19,9 %), kaptopriliu (19,5 %) ar valsartanu kartu su kaptopriliu (19,3 %) gydyt pacient grup se mirtingumas nuo bet kokios priežasties buvo panašus.
English: Treatment of symptomatic heart failure in adult patients when Angiotensin Converting Enzyme (ACE) inhibitors cannot be used, or as add-on therapy to ACE inhibitors when beta blockers cannot be used (see sections 4.4 and 5.1).
Lithuanian: Simptominio suaugusi j pacient širdies nepakankamumo gydymas, kai negalima vartoti angiotenzin konvertuojan io fermento (AKF) inhibitori , arba papildomas gydymas kartu su AKF inhibitoriais, kai negalima vartoti beta adrenoblokatori (žr.
English: Evaluation of patients with heart failure should always include assessment of renal function.
Lithuanian: Vertinant pacient , kuriems yra širdies nepakankamumas, b kl , taip pat visada reikia vertinti ir inkst funkcij .
English: Diovan belongs to a class of medicines known as angiotensin II receptor antagonist, which help to control high blood pressure.
Lithuanian: Diovan priklauso grupei vaist , kurie vadinami angiotenzino II receptori anatagonistais, jie padeda reguliuoti padid jus kraujosp d . Angiotenzinas II yra organizmo medžiaga, kuri sutraukia kraujagysles, tod l did ja kraujosp dis.
English: The safety profile of valsartan was consistent with the clinical course of patients treated in the postmyocardial infarction setting.
Lithuanian: Valsartano saugumas kito atitinkami, priklausomai nuo pacient , kurie buvo gydomi po miokardo infarkto, klinikin s b kl s kitimo.
English: Cardiac failure
Lithuanian: Širdies sutrikimai Nedažni
English: The combination of captopril and valsartan has shown no additional clinical benefit, instead the risk for adverse events increased compared to treatment with the respective therapies (see sections 4.2 and 5.1).
Lithuanian: Gydant kaptopriliu ir kartu valsartanu, klinikin nauda nebuvo didesn , nei gydant kiekvienu medikamentu atskirai, ta iau nepageidaujam reiškini rizika padid jo (žr.
English: Therefore, the combination of valsartan with an ACE inhibitor is not recommended.
Lithuanian: Tod l vienu metu gydymui skirti valsartan ir AKF inhibitori nerekomenduojama.
English: Regarding renal function, doubling of serum creatinine was observed in 4.2% of valsartan-treated patients, 4.8% of valsartan+captopril-treated patients, and 3.4% of captopril-treated patients.
Lithuanian: Vertinant inkst funkcij , kreatinino kiekis padvigub jo 4,2 % pacient , vartojusi vien valsartan , 4,8 % vartojusi valsartan kartu kaptopriliu ir 3,4 % vartojusi tik kaptopril . Gydymas d l vairi inkst funkcijos sutrikim nutrauktas 1,1 % pacient , vartojusi vien valsartano, 1,3 % vartojusi valsartan kartu kaptopriliu ir 0,8 % vartojusi tik kaptopril .
English: Use of Diovan in post-myocardial infarction patients commonly results in some reduction in blood pressure, but discontinuation of therapy because of continuing symptomatic hypotension is not usually necessary provided dosing instructions are followed (see section 4.2).
Lithuanian: Miokardo infarkto ištiktiems pacientams Diovan paprastai šiek tiek sumažina kraujosp d , ta iau d l išsilaikan ios simptomin s hipotenzijos gydymo dažniausiai nutraukti nereikia, jeigu doz sumažinama taip, kaip rekomenduojama (žr. 4.2 skyri ).
English: Paediatric population
Lithuanian: Senyvo amžiaus pacientai