FrancophonIA/ELRC3.0 huggingface dataset:
English: For the treatment of major depressive episodes in bipolar disorder Seroquel XR should be administered at bedtime.
Croatian: Za liječenje velikih depresivnih epizoda u bipolarnom poremećaju Seroquel XR je potrebno uzimati prije spavanja.
English: If you forget to take a dose of Seroquel XR
Croatian: Ako ste zaboravili uzeti Seroquel XR
English: (11) Cholesterol ≥240 mg/dL (≥6.2064 mmol/L) (patients ≥18 years of age) or ≥200 mg/dL (≥5.172 mmol/L) (patients <18 years of age) on at least one occasion.
Croatian: 11. Barem jednom izmjerena vrijednost kolesterola ≥ 240 mg/dL (≥ 6,2064 mmol/L) (bolesnici ≥ 18 godina starosti) ili ≥200 mg/dL (≥5,172 mmol/L) (bolesnici < 18 godina starosti).
English: • A serious blistering condition of the skin, mouth, eyes and genitals (Stevens-Johnson syndrome)
Croatian: • brzo oticanje kože, obično oko očiju, usana i u području ždrijela (angioedem) • ozbiljno stanje stvaranja mjehura na koži, ustima, očima i spolnim organima (Stevens-Johnsonov sindrom)
English: 10 tablets
Croatian: 10 tableta
English: In all clinical trials (placebo-controlled, open-label, active comparator) in patients with a baseline neutrophil count ≥1.5 X 109/L, the incidence of at least one occurrence of a shift to neutrophil count <1.5 x 109/L was 2.9% and to <0.5 X 109/L was 0.21% in patients treated with quetiapine.
Croatian: U svim kliničkim ispitivanjima (placebom kontroliranim, otvorenim ispitivanjima, ispitivanjima s aktivnim lijekom komparatorom) kod bolesnika koji su prije početka liječenja imali broj neutrofila ≥ 1,5 X 109/L, incidencija najmanje jedne pojave pomaka do broja neutrofila nižeg od <1,5 x 109/L je bila 2,9% i na <0,5 X 109/L je bila 0,21% kod bolesnika liječenih kvetiapinom.
English: SUMMARY OF PRODUCT CHARACTERISTICS, LABELLING AND PACKAGE LEAFLET
Croatian: Sažetak opisa svojstava lijeka, označavanje i uputa o lijeku
English: Elevations in serum aspartate aminotransferas e (AST) 3
Croatian: povećanja razine aspartat aminotransferaze (AST) u serumu žutica5, hepatitis
English: In a meta-analysis of atypical antipsychotics, it has been reported that elderly patients with dementiarelated psychosis are at an increased risk of death compared to placebo.
Croatian: U meta-analizi atipičnih antipsihotika, zabilježen je povećani rizik od smrti kod starijih bolesnika oboljelih od psihoze povezane s demencijom u usporedbi s kontrolnom skupinom koja je uzimala placebo.
English: This is because the combined effect of Seroquel and alcohol can make you sleepy.
Croatian: Seroquela i alkohola može učiniti pospanima.
English: • Women to have no monthly period or irregular periods.
Croatian: • izostanka mjesečnice ili neredovite mjesečnice kod žena.
English: This could increase the risk of accidental injury (fall)
Croatian: Ovo može povećati rizik ozljeda uslijed nezgode (pada) kod starijih bolesnika.
English: The dose should be adjusted within the effective dose range of 400 mg to 800 mg per day, depending on the clinical response and tolerability of the patient.
Croatian: Dozu je potrebno prilagoditi unutar raspona učinkovite doze od 400 do 800 mg dnevno, ovisno o kliničkom odgovoru i podnošljivosti kod pojedinog bolesnika.
English: The dosage should be increased daily with increments of 25-50 mg/day until an effective dosage, depending on the clinical response and tolerability of the individual patient.
Croatian: Dozu je potom potrebno svakoga dana povećavati za po 25 do 50 mg dnevno do postizanja učinkovite doze, ovisno o kliničkom odgovoru i podnošljivosti kod pojedinog bolesnika.
English: • Decrease in the amount of sodium in the blood
Croatian: • smanjenje količine natrija u krvi
English: (31) See Section 4.6.
Croatian: 31. Vidjeti dio 4.6.
English: Seroquel XR contains lactose
Croatian: Seroquel XR sadrži laktozu
English: Withdrawal (dis continuation) symptoms 1,9
Croatian: Opći poremećaji i reakcije na mjestu primjene simptomi ustezanja (prekida primjene lijeka)1, 9
English: Mild asthenia, peripheral oedema, irritability, pyrexia
Croatian: blaga astenija, periferni edem, razdražljivost, pireksija neuroleptički maligni sindrom1, hipotermija
English: Seroquel is not recommended for use in children and adolescents below 18 years of age, due to a lack of data to support use in this age group.
Croatian: Ne preporuča se primjena Seroquela u djece i adolescenata mlađih od 18 godina zbog nedostatka podataka koji bi poduprli primjenu u toj dobnoj skupini.
English: Elevations in serum triglyceride levels 10,30
Croatian: Poremećaji metabolizma i prehrane povećanja razine triglicerida u serumu10, 30
English: Quetiapine is well absorbed and extensively metabolised following oral administration.
Croatian: Apsorpcija Kvetiapin se nakon peroralne primjene dobro apsorbira i opsežno metabolizira.
English: See Section 5.1
Croatian: Vidjeti dio 5.1.
English: The most commonly reported Adverse Drug Reactions (ADRs) with quetiapine (≥10%) are somnolence, dizziness, headache, dry mouth, withdrawal (discontinuation) symptoms, elevations in serum triglyceride levels, elevations in total cholesterol (predominantly LDL cholesterol), decreases in HDL cholesterol, weight gain, decreased haemoglobin and extrapyramidal symptoms.
Croatian: suha usta, simptomi ustezanja (prekida primjene lijeka), porast razine triglicerida u serumu, porast razine ukupnog kolesterola (pretežno LDL kolesterola), smanjenje razine HDL kolesterola, povećanje tjelesne težine, smanjenje razine hemoglobina i ekstrapiramidni simptomi.
English: What Seroquel is and what it is used for
Croatian: Što se nalazi u ovoj uputi: Što je Seroquel i za što se koristi
English: Seroquel XR 50 mg, 150 mg, 200 mg, 300 mg, 400 mg prolonged-release tablets quetiapine
Croatian: Seroquel XR 50 mg, 150 mg, 200 mg, 300 mg, 400 mg tablete s produljenim oslobađanjem kvetiapin
English: The pharmacokinetics of lithium were not altered when co-administered with quetiapine.
Croatian: Farmakokinetika litija nije se promijenila kad se davao istodobno s kvetiapinom.
English: Inhibition of NET and partial agonist action at 5HT1A sites by norquetiapine may contribute to Seroquel's therapeutic efficacy as an antidepressant.
Croatian: 5HT1A receptora pridonosi terapijskoj djelotvornosti Seroquela kao antidepresiva.
English: Severe neutropenia (neutrophil count <0.5 X 109/L) has been reported in quetiapine clinical trials.
Croatian: U kliničkim ispitivanjima kvetiapina prijavljena je teška neutropenija (broj neutrofila <0,5 x 109/L).
English: • A combination of fever, severe muscle stiffness, sweating or a lowered level of consciousness (a disorder called “neuroleptic malignant syndrome).” Immediate medical treatment may be needed.
Croatian: • kombinaciju visoke tjelesne temperature (vrućice), teške ukočenosti mišića, znojenja ili smanjene razine svijesti (poremećaj koji se zove "neuroleptički maligni sindrom").
English: Seroquel XR is not recommended for use in children and adolescents below 18 years of age, due to a lack of data to support use in this age group.
Croatian: Ne preporuča se primjena Seroquela XR u djece i adolescenata mlađih od 18 godina zbog nedostatka podataka koji bi poduprli primjenu u toj dobnoj skupini.
English: 50 mg tablets are peach coloured; 150 mg tablets are white coloured, 200 mg tablets are yellow coloured; 300 mg tablets are pale yellow coloured and 400 mg tablets are white coloured.
Croatian: Sve tablete s produljenim oslobađanjem su oblika kapsule s utisnutim oznakom “XR” i oznakom jačine.Tablete od 50 mg su boje breskve, tablete od 150 mg su bijele boje, tablete od 200 mg su žute boje, tablete od 300 mg su svijetložute boje, a tablete od 400 mg su bijele boje.
English: Triglycerides ≥200 mg/dL (≥2.258 mmol/L) (patients ≥18 years of age) or ≥150 mg/dL (≥1.694 mmol/L)
Croatian: Barem jednom izmjerena vrijednost triglicerida ≥ 200 mg/dL (≥ 2,258 mmol/L) (bolesnici ≥ 18 godina starosti) ili ≥150 mg/dL (≥1,694 mmol/L) (bolesnici < 18 godina starosti).
English: In placebo-controlled clinical trials with children and adolescent patients, quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for schizophrenia, bipolar mania, and bipolar depression (see section 4.8).
Croatian: U placebom kontroliranim kliničkim ispitivanjima, u kojima su sudjelovala djeca i adolescenti, kvetiapin je bio povezan s povećanom incidencijom ekstrapiramidnih simptoma u usporedbi s placebom u bolesnika liječenih zbog shizofrenije, bipolarne manije i bipolarne depresije (vidjeti dio 4.8).
English: Inhibition of NET and partial agonist action at 5HT1A sites by norquetiapine may contribute to Seroquel XR's therapeutic efficacy as an antidepressant.
Croatian: 5HT1A receptora pridonosi terapijskoj djelotvornosti Seroquela XR kao antidepresiva.
English: 1 blister of 6 tablets
Croatian: 1 blister sa 6 tableta
English: In placebo controlled clinical trials of adult patients quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for major depressive episodes in bipolar disorder and major depressive disorder (see sections 4.8 and 5.1).
Croatian: U placebom kontroliranim kliničkim ispitivanjima odraslih bolesnika kvetiapin je povezan s povećanom incidencijom ekstrapiramidnih simptoma (EPS) u usporedbi s placebom u bolesnika liječenih od velikih depresivnih epizoda u bipolarnom poremećaju i u velikom depresivnom poremećaju (vidjeti dio 4.8 i 5.1).
English: 24 blisters of 10 tablets (150 mg and 300 mg tablets only)
Croatian: 24 blistera s 10 tablets (samo za tablete od 150 mg i 300 mg)
English: For the treatment of major depressive episodes in bipolar disorder Seroquel should be administered once daily at bedtime.
Croatian: Za liječenje velikih depresivnih epizoda u bipolarnom poremećaju Seroquel je potrebno uzimati jednom dnevno prije spavanja.
English: Very rare side effects (may affect up to 1 in 10,000 people):
Croatian: Vrlo rijetke nuspojave (mogu se javiti u do 1 na 10 000 osoba):
English: In placebo controlled clinical trials of adult patients quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for major depressive episodes in bipolar disorder(see sections 4.8 and 5.1).
Croatian: U placebom kontroliranim kliničkim ispitivanjima odraslih bolesnika, kvetiapin je povezan s povećanom incidencijom ekstrapiramidnih simptoma (EPS) u usporedbi s placebom u bolesnika liječenih od velikih depresivnih epizoda u bipolarnom poremećaju (vidjeti dijelove 4.8 i 5.1).
English: • Do not drink grapefruit juice while you are taking Seroquel XR.
Croatian: • Tijekom liječenja Seroquelom XR nemojte piti sok od grejpa.
English: INFORMATION IN BRAILLE Seroquel 25 mg, 100 mg and 200 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Seroquel 25 mg, 100 mg i 200 mg
English: If you do, your doctor may check your blood sugar levels while you are taking Seroquel.
Croatian: U tom slučaju, tijekom liječenja Seroquelom liječnik Vam može provjeravati razinu šećera u krvi.
English: In all short-term placebo-controlled monotherapy trials in patients with a baseline neutrophil count ≥1.5 X 109/L, the incidence of at least one occurrence of a shift to neutrophil count <1.5 X 109/L, was 1.9% in patients treated with quetiapine compared to 1.5% in placebo-treated patients.
Croatian: U svim kratkoročnim, placebo-kontroliranim kliničkim ispitivanjima u kojima je Seroquel primjenjivan kao monoterapija, incidencija najmanje jedne pojave pomaka do broja neutrofila nižeg od 1,5 X 109/L, kod bolesnika koji su prije početka liječenja imali broj neutrofila ≥ 1,5 X 109/L, je bila 1,9% u skupini bolesnika koji su liječeni kvetiapinom u usporedbi s 1,5% kod bolesnika liječenih placebom.
English: Day 4 morning evening 25 mg 2x25 mg 100 mg 200 mg
Croatian: 25 mg 2x25 mg 100 mg 200 mg
English: The efficacy of Seroquel XR was further demonstrated with significance versus placebo in an additional 3 week study.
Croatian: U dodatnom trotjednom ispitivanju je Seroquel XR pokazao značajnu razliku u djelotvornosti u odnosu na placebo.
English: In a 6-week, randomised, study of lithium and SEROQUEL XR versus placebo and SEROQUEL XR in adult patients with acute mania, the difference in YMRS mean improvement between the lithium add-on group and the placebo add-on group was 2.8 points and the difference in % responders (defined as 50% improvement from baseline on the YMRS) was 11% (79% in the lithium add-on group vs. 68% in the placebo add-on group).
Croatian: naspram placeba i lijeka Seroquel XR u odraslih bolesnika s akutnom manijom, razlika u srednjoj vrijednosti poboljšanja rezultata na YMRS (Young Mania Rating Scale) ljestvici između skupine kojoj je dodavan litij i skupine kojoj je dodavan placebo iznosila je 2,8 bodova, a razlika u postotku bolesnika koji su odgovorili na liječenje (što je definirano kao poboljšanje za 50% od početnog rezultata na YMRS
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Seroquel 25 mg contains 25 mg quetiapine (as quetiapine fumarate) Excipient : 18 mg lactose (anhydrous) per tablet
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Seroquel 25 mg sadržava 25 mg kvetiapina (u obliku kvetiapinfumarata).
English: If you forget to take a dose of Seroquel
Croatian: Ako ste zaboravili uzeti Seroquel
English: In placebo-controlled studies in elderly patients with dementia-related psychosis, the incidence of cerebrovascular adverse events per 100 patient years was not higher in quetiapine-treated patients than in placebo-treated patients.
Croatian: incidencija cerebrovaskularnih štetnih događaja na 100 bolesnik-godina nije bila viša u bolesnika liječenih kvetiapinom u odnosu na bolesnike koji su dobivali placebo.
English: Cases of QT prolongation, ventricular arrhythmia, sudden unexplained death, cardiac arrest and torsades de pointes have been reported with the use of neuroleptics and are considered class effects.
Croatian: Pri primjeni neuroleptika zabilježeni su slučajevi produljenja QT-intervala, ventrikularnih aritmija, iznenadne neobjašnjive smrti, srčanog zastoja i aritmije poznate pod nazivom "torsades de pointes".
English: Based on shifts from normal baseline to potentially clinically important value at anytime post-baseline in all trials.
Croatian: Temeljeno na pomaku sa normalnih početnih vrijednosti na potencijalno klinički važne vrijednosti u bilo kojem trenutku tijekom primjene lijeka u svim ispitivanjima.
English: 100 mg/day; subsequently the dose was titrated to a target dose (mania 400-600 mg/day; schizophrenia 400-800 mg/day) using increments of 100 mg/day given two or three times daily.
Croatian: primijenjeno dva ili tri puta dnevno do ciljane doze (manija 400-600 mg dnevno; shizofrenija 400-800 mg dnevno).
English: (27) Based on shifts from normal baseline to potentially clinically important value at anytime post-baseline in all trials.
Croatian: 27. Temeljeno na pomaku sa normalnih početnih vrijednosti na potencijalno klinički važne vrijednosti u bilo kojem trenutku tijekom primjene lijeka u svim ispitivanjima.
English: Seroquel® 200 mg Filmtabletten, Seroquel® 300 mg Filmtabletten
Croatian: Seroquel® 25 mg Filmtabletten, Seroquel® 100 mg Filmtabletten, Seroquel® 200 mg Filmtabletten, Seroquel® 300 mg Filmtabletten
English: In this study patients randomised to Seroquel XR received 50 mg/day on Days 1-3, the dose could be increased to 100 mg/day on Day 4, 150 mg/day on Day 8 and up to 300 mg/day depending on clinical response and tolerability.
Croatian: mg/dnevno prvi, drugi i treći dan, a doza se mogla povećati na 100 mg/dnevno četvrti dan, na 150 mg/dnevno osmi dan i do 300 mg/dnevno ovisno o kliničkom odgovoru i podnošljivosti.
English: Fasting blood glucose ≥126 mg/dL (≥7.0 mmol/L) or a non fasting blood glucose ≥200 mg/dL (≥11.1 mmol/L) on at least one occasion.
Croatian: Barem jednom izmjerena vrijednost glukoze u krvi natašte ≥ 126 mg/dL (≥ 7,0 mmol/L), ili barem jednom izmjerena vrijednost glukoze u krvi nakon uzimanja obroka ≥ 200 mg /dL (≥ 11,1 mmol/L).
English: The dose can be increased in increments of 50 mg/day to an effective dose, depending on the clinical response and tolerability of the individual patient.
Croatian: Doza se može povećavati za 50 mg dnevno do postizanja učinkovite doze, ovisno o kliničkom odgovoru i podnošljivosti kod pojedinog bolesnika.
English: Day 3 morning evening 25 mg 2x25 mg 100 mg
Croatian: 25 mg 2x25 mg 100 mg
English: Patients with hepatic impairment should be started on 50 mg/day.
Croatian: U bolesnika s oštećenom funkcijom jetre, liječenje se mora započeti dozom od 50 mg dnevno.
English: Increases in triglycerides, LDL and total cholesterol, and decreases in HDL cholesterol have been observed in clinical trials with quetiapine (see section 4.8).
Croatian: U kliničkim ispitivanjima kvetiapina primijećen je porast razine triglicerida, LDL-a i ukupnog kolesterola, te smanjenje razine HDL-kolesterola (vidjeti dio 4.8).
English: Tablet core : povidone, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, sodium starch glycollate Type A, lactose monohydrate, magnesium stearate Tablet coating: hypromellose, macrogol, titanium dioxide (E171).
Croatian: Jezgra tablete: povidon, kalcijev hidrogenfosfat dihidrat, mikrokristalična celuloza, natrijev škroboglikolat vrste A, laktoza hidrat, magnezijev stearat.
English: Also caution should be exercised when quetiapine is prescribed either with medicines known to increase QT interval, or with concomitant neuroleptics, especially in the elderly, in patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalaemia or hypomagnesaemia (see section 4.5).
Croatian: Također je nužan oprez pri propisivanju kvetiapina s lijekovima za koje je poznato da produžuju QT interval te pri istodobnoj primjeni neuroleptika, naročito u starijih, u bolesnika: s kongenitalnim sindromom produljenog QT intervala, kongestivnim srčanim zatajenjem, hipertrofijom srca,
English: 18 blisters of 10 tablets (150 mg and 300 mg tablets only)
Croatian: 18 blistera s 10 tableta (samo za tablete od 150 mg i 300 mg)
English: The symptoms of tardive dyskinesia can worsen or even arise after discontinuation of treatment (see Section 4.8).
Croatian: Simptomi tardivne diskinezije mogu se pogoršati ili čak pojaviti nakon prestanka terapije
English: The total daily dose for the first four days of therapy is 100 mg (Day 1), 200 mg (Day 2), 300 mg (Day 3) and 400 mg (Day 4).
Croatian: Ukupna dnevna doza za prva četiri dana terapije iznosi kako slijedi: 100 mg (prvi dan), 200 mg (drugi dan), 300 mg (treći dan) i 400 mg (četvrti dan).
English: NAME OF THE MEDICINAL PRODUCT Seroquel 100 (or 150 mg, or 200 mg or 300 mg) mg film-coated tablets quetiapine
Croatian: Seroquel 100 mg (ili 150 mg, ili 200 mg, ili 300 mg) filmom obložene tablete kvetiapin
English: Dry mouth
Croatian: • začepljen nos
English: Elevations in serum alanine aminotransferas e (ALT)3, Elevatio ns in gammaGT levels3
Croatian: Poremećaji jetre i žući povećanja razine alanin aminotransfer aze (ALT) u serumu3,
English: Constipation and intestinal obstruction have been reported with quetiapine (see section 4.8 Undesirable effects).
Croatian: Konstipacija i opstrukcija crijeva prijavljene su kod primjene kvetiapina (vidjeti dio 4.8 Nuspojave).
English: Dyspnoea 23
Croatian: disfagija7
English: See leaflet for further information.
Croatian: Za daljnje informacije vidjeti Uputu o lijeku.
English: • Shortness of breath.
Croatian: • nedostatak zraka
English: INFORMATION IN BRAILLE Seroquel 25 mg and 100 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Seroquel 25 mg i 100 mg
English: Respiratory, thoracic and mediastinal disorder
Croatian: Poremećaji dišnog sustava, prsišta i sredoprsja dispneja rinitis
English: The total daily dose for the first four days of therapy is 50 mg (Day 1), 100 mg (Day 2), 200 mg (Day 3) and 300 mg (Day 4).
Croatian: Ukupna dnevna doza za prva četiri dana liječenja iznosi 50 mg (prvi dan), 100 mg (drugi dan), 200 mg (treći dan) i 300 mg (četvrti dan).
English: 12 blisters of 10 tablets (150 mg and 300 mg tablets only)
Croatian: 12 blistera s 10 tableta (samo za tablete od 150 mg i 300 mg)
English: • Inflammation of the pancreas
Croatian: • razdražljivost Prijavljivanje nuspojava
English: INFORMATION IN BRAILLE Seroquel 25 mg
Croatian: 16. PODACI NA BRAILLEOVOM PISMU Seroquel 25 mg
English: Calcium Hydrogen Phosphate Dihydrate Microcrystalline Cellulose Sodium Starch Glycolate Type A Lactose Monohydrate Magnesium Stearate
Croatian: Jezgra povidon kalcijev hidrogenfosfat dihidrat celuloza, mikrokristalična natrijev škroboglikolat, vrste A laktoza hidrat magnezijev stearat
English: Therefore, Seroquel XR should be used with caution in patients with known hepatic impairment, especially during the initial dosing period.
Croatian: Kvetiapin se opsežno metabolizira u jetri te se stoga Seroquel XR mora s oprezom davati bolesnicima s poznatim oštećenjem funkcije jetre, naročito tijekom početnog razdoblja doziranja.
English: 100 film-coated tablets
Croatian: 100 filmom obloženih tableta
English: Seroquel was administered twice-daily totalling 400 mg to 800 mg a day as combination therapy to lithium or valproate.
Croatian: Seroquel je davan kao kombinirano liječenje s litijem ili valproatom dvaput dnevno u ukupnoj dozi od 400 mg do 800 mg na dan.
English: For the treatment of moderate to severe manic episodes in bipolar disorder For the treatment of manic episodes associated with bipolar disorder, Seroquel should be administered twice a day.
Croatian: Za liječenje maničnih epizoda povezanih s bipolarnim poremećajem, Seroquel je potrebno uzimati dva puta dnevno.
English: If you do, your doctor may check your blood sugar levels while you are taking Seroquel XR.
Croatian: U tom slučaju, tijekom liječenja Seroquelom XR liječnik Vam može provjeravati razinu šećera u krvi.
English: PACKAGE LEAFLET
Croatian: Sadržaj pakiranja
English: Very Common side effects (may affect more than 1 in 10 people):
Croatian: Vrlo česte nuspojave (mogu se javiti u više od 1 na 10 osoba):
English: Blood and lymphatic system disorders
Croatian: Poremećaji krvi i limfnog sustava smanjena razina hemoglobina22
English: Platelets ≤100 x 109/L on at least one occasion 14.
Croatian: 13. Barem jednom izmjerena vrijednost trombocita ≤ 100 x 109/L 14.
English: Constipation and intestinal obstruction
Croatian: Konstipacija i opstrukcija crijeva
English: Seroquel XR dose can be adjusted depending on clinical response and tolerability of the individual patient within the dose range of 300 mg to 800 mg/day.
Croatian: Doza Seroquela XR se može prilagoditi u rasponu od 300 mg do 800 mg dnevno, ovisno o kliničkom odgovoru i podnošljivosti kod pojedinog bolesnika.
English: Treatment with quetiapine should be reassessed in patients with suspected cardiomyopathy or myocarditis.
Croatian: U bolesnika u kojih se sumnja na kardiomiopatiju ili miokarditis treba ponovno procijeniti liječenje kvetiapinom.
English: Prolactin levels (patients>18 years of age): >20 µg/L (>869.56 pmol/L) males; >30 µg/L (>1304.34 pmol/L) females at any time 16.
Croatian: 15. Razina prolaktina (bolesnici > 18 godina) u bilo kojem trenutku: > 20µg/L (> 869,56 pmol/L) muškarci; >
English: Seroquel XR 50 mg prolonged-release tablets Seroquel XR 150 mg prolonged-release tablets Seroquel XR 200 mg prolonged-release tablets Seroquel XR 300 mg prolonged-release tablets Seroquel XR 400 mg prolonged-release tablets
Croatian: Seroquel XR 50 mg tablete s produljenim oslobađanjem Seroquel XR 150 mg tablete s produljenim oslobađanjem Seroquel XR 200 mg tablete s produljenim oslobađanjem Seroquel XR 300 mg tablete s produljenim oslobađanjem Seroquel XR 400 mg tablete s produljenim oslobađanjem
English: Musculoskeletal and connective tissue disorders
Croatian: Poremećaji mišićno koštanog sustava i vezivnog tkiva rabdomioliza
English: Quetiapine was administered twice-daily totalling 400 mg to 800 mg a day as combination therapy to lithium or valproate.
Croatian: Kvetiapin je davan kao kombinirana terapija s litijem ili valproatom dvaput dnevno u ukupnoj dozi od 400 mg do 800 mg na dan.