FrancophonIA/ELRC3.0 huggingface dataset:
English: The other ingredients are: hydroxypropyl cellulose, sucralose, saccharin sodium, sodium citrate dihydrate, mannitol, yellow iron oxide, monoammonium glycyrrhizinate, sorbitol (E420), fructose, natural and artificial flavours (orange, banana, and masking), aspartame (E951), crospovidone Type A, magnesium stearate, sodium stearyl fumarate, ethylcellulose 20 cP, ammonium hydroxide, medium chain triglycerides, oleic acid, hypromellose 2910/6cP and macrogol/PEG 400.
Croatian: Drugi sastojci su: hidroksipropilceluloza, sukraloza, saharinnatrij, natrijev citrat dihidrat, manitol, žuti željezov oksid, amonijev glicirizat, sorbitol (E420), fruktoza, prirodne i umjetne arome (naranča, banana i aroma za maskiranje okusa), aspartam (E951), krospovidon tipa A, magnezijev stearat, natrijev stearilfumarat, etilceluloza 20 cP, amonijev hidroksid, trigliceridi srednje duljine lanca, oleatna kiselina, hipromeloza 2910/6cP i makrogol/PEG 400.
English: ISENTRESS 100 mg granules for oral suspension
Croatian: ISENTRESS 100 mg granule za oralnu suspenziju
English: Snap the lid of the mixing cup shut.
Croatian: Zatvorite čašu za miješanje poklopcem.
English: Each film-coated tablet contains 600 mg of raltegravir (as potassium).
Croatian: Jedna filmom obložena tableta sadrži 600 mg raltegravira (u obliku raltegravirkalija).
English: Each film-coated tablet contains 400 mg of raltegravir (as potassium).
Croatian: Jedna filmom obložena tableta sadrži 400 mg raltegravira (u obliku raltegravirkalija).
English: No hepatic impairment study has been conducted with raltegravir 1,200 mg once daily, however, based on results with the 400 mg twice daily tablet, no clinically meaningful effect is expected for mild and moderate hepatic impairment.
Croatian: Međutim, s obzirom na rezultate kod primjene tablete od 400 mg dvaput na dan ne očekuje se klinički značajan učinak kod blagog i umjerenog oštećenja funkcije jetre.
English: raltegravir AUC  55% raltegravir C12 hr  32% raltegravir Cmax  52%
Croatian: raltegravir AUC  55% raltegravir C12h  32% raltegravir Cmax  52%
English: 100 mg chewable tablets:
Croatian: Tablete za žvakanje od 100 mg:
English: 6 hours before raltegravir raltegravir AUC  13% raltegravir C12 hr  50% raltegravir Cmax  10%
Croatian: 6 sati prije raltegravira raltegravir AUC  13% raltegravir C12h  50% raltegravir Cmax  10%
English: Therefore, co-administration of raltegravir with aluminium and/or magnesium containing antacids is not recommended.
Croatian: Iz toga se razloga istodobna primjena raltegravira s antacidima koji sadrže aluminij i/ili magnezij ne preporučuje.
English: 2 hours after raltegravir raltegravir AUC  30 % raltegravir C12 hr  57 % raltegravir Cmax  24 %
Croatian: 2 sata nakon raltegravira raltegravir AUC  30% raltegravir C12h  57% raltegravir Cmax  24%
English: 0.8 mL (8 mg) twice daily
Croatian: 0,8 ml (8 mg) dvaput na dan od 3 do manje od 4
English: raltegravir AUC ↑ 44 % raltegravir C12 hr ↑ 6 % raltegravir Cmax ↑ 60 %
Croatian: raltegravir AUC ↑ 44% raltegravir C12h ↑ 6% raltegravir Cmax ↑ 60%
English: raltegravir AUC  24 % raltegravir C12hr  55 % raltegravir Cmax  18 %
Croatian: raltegravir AUC  24% raltegravir C12h  55% raltegravir Cmax  18%
English: Uncommon asthenia, fatigue, pyrexia chest discomfort, chills, face oedema, fat tissue increased, feeling jittery, malaise, submandibular mass, oedema peripheral, pain
Croatian: Opći poremećaji i reakcije na mjestu primjene često manje često astenija, umor, pireksija nelagoda u prsima, zimica, edem lica, nakupljanje masnog tkiva, osjećaj nervoze, malaksalost, submandibularna nakupina, periferni edem, bol
English: raltegravir AUC  40 % raltegravir C12hr  61 % raltegravir Cmax  38 %
Croatian: raltegravir AUC  40% raltegravir C12h  61% raltegravir Cmax  38%
English: Each tablet contains 25 mg of raltegravir (as potassium).
Croatian: Jedna tableta sadrži 25 mg raltegravira (u obliku raltegravirkalija).
English: No dose adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily).
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan).
English: Baseline Characteristic HIV-RNA > 100,000 copies/mL ≤ 100,000 copies/mL CD4-count ≤ 50 cells/mm > 50 and ≤ 200 cells/mm > 200 cells/mm Sensitivity score (GSS)
Croatian: ≤ 100 000 kopija/ml Broj CD4 stanica ≤ 50 stanica/mm > 50 i ≤ 200 stanica/mm > 200 stanica/mm Indeks genotipske osjetljivosti (GSS)
English: Ask your doctor, pharmacist or nurse for advice before taking any medicine if you are pregnant or breast-feeding.
Croatian: Ako ste trudni ili dojite, obratite se svom liječniku, ljekarniku ili medicinskoj sestri za savjet prije nego uzmete bilo koji lijek.
English: Chewable tablet 25 mg Pale yellow, round, chewable tablet with MSD corporate logo on one side and “473” on the other side.
Croatian: Blijedožuta, okrugla tableta za žvakanje, s logotipom tvrtke MSD na jednoj i oznakom "473" na drugoj strani.
English: Percent HIV-RNA < 50 copies/mL (95 % CI)
Croatian: Postotak s < 50 HIV-RNK kopija/ml (95% CI)
English: 12 hours after raltegravir raltegravir AUC  10% raltegravir C24 hr  57% raltegravir Cmax  2%
Croatian: 12 sati nakon primjene raltegravira raltegravir AUC  10% raltegravir C24h  57% raltegravir Cmax  2%
English: calcium carbonate antacid (raltegravir 400 mg Twice Daily)
Croatian: antacid s kalcijevim karbonatom (raltegravir 400 mg dvaput na dan)
English: Cancers were reported in treatment-experienced and treatment-naïve patients who initiated raltegravir in conjunction with other antiretroviral agents.
Croatian: U prethodno liječenih i još neliječenih bolesnika, koji su započeli liječenje raltegravirom u kombinaciji s drugim antiretrovirusnim lijekovima, prijavljeni su slučajevi raka.
English: METAL CATION ANTACIDS aluminium and magnesium hydroxide antacid (raltegravir 400 mg Twice Daily)
Croatian: ANTACIDI KOJI SADRŽE KATIONE METALA antacid s aluminijevim i magnezijevim hidroksidom (raltegravir 400 mg dvaput na dan)
English: ISENTRESS 600 mg film-coated tablets
Croatian: ISENTRESS 600 mg filmom obložene tablete
English: raltegravir AUC  10 % raltegravir C12hr  34 % raltegravir Cmax  11 %
Croatian: raltegravir AUC  10% raltegravir C12h  34% raltegravir Cmax  11%
English: Refer to the chewable tablet and granules for oral suspension SmPCs for additional dosing information.
Croatian: Za dodatne informacije o doziranju, pročitajte sažetke opisa svojstava lijeka za tablete za žvakanje i granule za oralnu suspenziju.
English: ISENTRESS 400 mg film-coated tablets
Croatian: ISENTRESS 400 mg filmom obložene tablete
English: Extrapolated from 400 mg twice daily study
Croatian: Ekstrapolirano iz ispitivanja raltegravira od 400 mg dvaput na dan.
English: ISENTRESS 100 mg chewable tablets raltegravir
Croatian: Isentress 100 mg tablete za žvakanje raltegravir
English: Durable outcomes (Week 48 and Week 96) for patients on the recommended dose raltegravir 400 mg twice daily from the pooled studies BENCHMRK 1 and BENCHMRK 2 are shown in Table 2.
Croatian: U Tablici 4 prikazani su dugotrajni ishodi (48. i 96. tjedan) liječenja bolesnika koji su primali preporučenu dozu raltegravira 400 mg dvaput na dan, iz objedinjenih ispitivanja BENCHMRK 1 i BENCHMRK 2.
English: famotidine (raltegravir 400 mg Twice Daily)
Croatian: famotidin (raltegravir 400 mg dvaput na dan)
English: Uncommon arthralgia, arthritis, back pain, flank pain, musculoskeletal pain, myalgia, neck pain, osteopenia, pain in extremity, tendonitis, rhabdomyolysis
Croatian: Poremećaji mišićnokoštanog sustava i vezivnog tkiva manje često artralgija, artritis, bol u leđima, bol u slabinama, bol u kostima i mišićima, mialgija, bol u vratu, osteopenija, bol u ekstremitetima, tendinitis, rabdomioliza
English: Carton for the 25 mg chewable tablets
Croatian: Kutija za 25 mg tablete za žvakanje
English: raltegravir AUC  4% raltegravir C12hr  25% raltegravir Cmax  11%
Croatian: raltegravir AUC  4% raltegravir C12h  25% raltegravir Cmax  11%
English: Isentress 100 mg granules for oral suspension raltegravir
Croatian: ISENTRESS 100 mg granule za oralnu suspenziju raltegravir
English: How to store Isentress
Croatian: Kako čuvati Isentress
English: 0.4 mL (4 mg) once daily
Croatian: 0,4 ml (4 mg) jedanput na dan od 3 do manje od 4
English: Gender, race and BMI
Croatian: Spol, rasa i indeks tjelesne mase
English: Weight based dosing, see dosing Table 1
Croatian: ≥ 25 kg tableta za žvakanje doziranje na temelju tjelesne težine, vidjeti Tablicu 1
English: Do not switch between the granules for oral suspension, chewable tablet, 600 mg tablet or 400 mg tablet without first talking to your child's doctor, pharmacist or nurse.
Croatian: Nemojte prelaziti s granula za oralnu suspenziju na tablete za žvakanje, tablete od 600 mg ili tablete od 400 mg i obrnuto ako prethodno niste o tome razgovarali s djetetovim liječnikom, ljekarnikom ili medicinskom sestrom.
English: Carton for 400 mg film-coated tablets
Croatian: Kutija za 400 mg filmom obložene tablete
English: Each chewable tablet contains 25 mg of raltegravir (as potassium).
Croatian: Jedna tableta za žvakanje sadrži 25 mg raltegravira (u obliku raltegravirkalija).
English: Anti-retroviral Pregnancy Registry
Croatian: ANTIRETROVIRUSNI
English: Weight based dosing, see dosing tables for the chewable tablet
Croatian: ≥ 25 kg tableta za žvakanje doziranje na temelju tjelesne težine, vidjeti tablice za doziranje tableta za žvakanje 9
English: Co-administration of atazanavir with raltegravir 1,200 mg once daily significantly increased plasma levels of raltegravir; therefore, co-administration of raltegravir 1,200 mg once daily and atazanavir is not recommended.
Croatian: Stoga se istodobna primjena raltegravira u dozi od 1200 mg jedanput na dan i atazanavira ne preporučuje.
English: ISENTRESS is also available in a chewable tablet formulation and in granules for oral suspension formulation.
Croatian: ISENTRESS je dostupan i u obliku tableta za žvakanje te u obliku granula za oralnu suspenziju.
English: Do not switch between the 600 mg tablet, 400 mg tablet, chewable tablet or granules for oral suspension without first talking with your doctor, pharmacist or nurse.
Croatian: Nemojte prelaziti s tableta od 600 mg na tablete od 400 mg, tablete za žvakanje ili granule za oralnu suspenziju i obrnuto ako prethodno niste o tome razgovarali sa svojim liječnikom, ljekarnikom ili medicinskom sestrom.
English: raltegravir AUC  49% raltegravir C12hr  3% raltegravir Cmax ↑ 64%
Croatian: raltegravir AUC  49% raltegravir C12h  3% raltegravir Cmax ↑ 64%
English: The risk of developing cancer in these studies was similar in the groups receiving raltegravir and in the groups receiving comparators.
Croatian: U tim su ispitivanjima skupine koje su primale raltegravir i skupine koje su primale usporedne lijekove imale sličan rizik za razvoj raka.
English: raltegravir AUC  49% raltegravir C12 hr  63% raltegravir Cmax  44%
Croatian: raltegravir AUC  49% raltegravir C12h  63% raltegravir Cmax  44%
English: † 10 mL (100 mg) twice daily 1 x 100 mg twice daily 20 to less than 25
Croatian: 1 ml (10 mg) dvaput na dan od 4 do manje od 5
English: Do not switch between the 400 mg tablet, the 600 mg tablet, chewable tablet or granules for oral suspension without first talking with your doctor, pharmacist or nurse.
Croatian: Nemojte prelaziti s tableta od 400 mg na tablete od 600 mg, tablete za žvakanje ili granule za oralnu suspenziju i obrnuto ako prethodno niste o tome razgovarali sa svojim liječnikom, ljekarnikom ili medicinskom sestrom.
English: Isentress is also available in a 400 mg tablet, a 600 mg tablet and in granules for oral suspension.
Croatian: Isentress je dostupan i u obliku tableta od 400 mg, tableta od 600 mg te granula za oralnu suspenziju.
English: Carton for ISENTRESS 100 mg granules for oral suspension
Croatian: Kutija za ISENTRESS 100 mg granule za oralnu suspenziju
English: vomiting; indigestion; belching
Croatian: probavne smetnje; podrigivanje
English: Each chewable tablet contains 100 mg of raltegravir (as potassium).
Croatian: Jedna tableta za žvakanje sadrži 100 mg raltegravira (u obliku raltegravirkalija).
English: Carton for 600 mg film-coated tablets
Croatian: Kutija za 600 mg filmom obložene tablete
English: There was no clinically meaningful effect of age on raltegravir pharmacokinetics over the age range studied in ONCEMRK with raltegravir 1,200 mg (2 x 600 mg) once daily.
Croatian: U ispitivanjima interakcija efavirenz nije imao klinički značajan utjecaj na farmakokinetiku raltegravira u dozi od 1200 mg jedanput na dan.
English: STARTMRK (multi-centre, randomised, double-blind, active-control trial) evaluated the safety and anti-retroviral activity of raltegravir 400 mg twice daily vs. efavirenz 600 mg at bedtime, in a combination with emtricitabine (+) tenofovir disoproxil fumarate, in treatment-naïve HIV-infected patients with HIV RNA > 5,000 copies/mL.
Croatian: U ispitivanju STARTMRK (multicentrično, randomizirano, dvostruko slijepo, aktivnim lijekom kontrolirano ispitivanje) ocjenjivale su se sigurnost i antiretrovirusna aktivnost raltegravira u dozi od 400 mg dvaput na dan naspram efavirenza u dozi od 600 mg primijenjenim navečer prije spavanja, u kombinaciji s emtricitabinom (+) tenofovirdizoproksilfumaratom u bolesnika s HIV infekcijom s > 5000 HIV-RNK kopija/ml koji prethodno nisu bili liječeni.
English: Percent HIV-RNA < 50 copies/mL (95 % CI) All patients
Croatian: Postotak bolesnika s < 40 HIV-RNK kopija/ml (95% CI) Svi bolesnici
English: Response
Croatian: Doziranje
English: Isentress is also available in a 600 mg tablet, a chewable tablet and in granules for oral suspension.
Croatian: Isentress je dostupan i u obliku tableta od 600 mg, tableta za žvakanje te granula za oralnu suspenziju.
English: Co-administration of raltegravir 1,200 mg once daily with calcium carbonate and aluminium/magnesium containing antacids resulted in reduced raltegravir plasma levels; therefore, co-administration is not recommended (see section 4.5).
Croatian: Istodobna primjena raltegravira u dozi od 1200 mg jedanput na dan s antacidima koji sadrže kalcijev karbonat i aluminij/magnezij rezultirala je sniženim koncentracijama raltegravira u plazmi.
English: Baseline Characteristic HIV-RNA > 100,000 copies/mL ≤ 100,000 copies/mL CD4-count ≤ 50 cells/mm
Croatian: ≤ 100 000 kopija/ml Broj CD4 stanica ≤ 50 stanica/mm > 50 i
English: No dose adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily) or etravirine.
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan) ili etravirina.
English: Inducers of drug metabolizing enzymes
Croatian: ANTIMIKROBNI LIJEKOVI Antimikobakterijski lijekovi
English: • Prescribing leaflet
Croatian: Prijavljivanje nuspojava
English: Percent HIV-RNA < 40 copies/mL (95 % CI)
Croatian: Postotak s < 400 HIV-RNK kopija/ml (95% CI)
English: Raltegravir was not teratogenic in developmental toxicity studies in rats and rabbits.
Croatian: U ispitivanjima razvojne toksičnosti na štakorima i kunićima raltegravir se nije pokazao teratogenim.
English: Each tablet contains 600 mg of raltegravir (as potassium).
Croatian: Jedna tableta sadrži 600 mg raltegravira (u obliku raltegravirkalija).
English: The exposure-adjusted rates of rash (all causality) were 10.9, 4.2, and 3.8 per 100 patient-years (PYR), respectively; and for drug-related rash were 2.4, 1.1, and 2.3 per 100 PYR, respectively.
Croatian: Stope osipa (bilo kojeg uzroka) prilagođene s obzirom na izloženost iznosile su 10,9 na 100 bolesnik-godina u bolesnika koji su primali raltegravir + darunavir, 4,2 na 100 bolesnik-godina u bolesnika koji su primali raltegravir bez darunavira i 3,8 na 100 bolesnikgodina u bolesnika koji su primali darunavir bez raltegravira; dok su za osip povezan s lijekom u te tri skupine stope iznosile 2,4; 1,1 odnosno 2,3 na 100 bolesnik-godina.
English: No dose adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily) or boceprevir.
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan) ili boceprevira.
English: Each tablet contains 400 mg of raltegravir (as potassium).
Croatian: Jedna tableta sadrži 400 mg raltegravira (u obliku raltegravirkalija).
English: Refer to the 600 mg tablet SmPCs for additional dosing information.
Croatian: Za dodatne informacije o doziranju pročitajte sažetak opisa svojstava lijeka za tablete od 600 mg.
English: No dosage adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily) or midazolam.
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan) ili midazolama.
English: The exposure-adjusted rates of rash (all causality) were 10.9, 4.2, and 3.8 per 100 patient-years (PYR), respectively; and for drug-related rash were 2.4, 1.1, and 2.3
Croatian: Stope osipa (bilo kojeg uzroka) prilagođene s obzirom na izloženost iznosile su 10,9 na 100 bolesnik-godina u bolesnika koji su primali raltregravir + darunavir, 4,2 na
English: Each tablet contains 100 mg of raltegravir (as potassium).
Croatian: Jedna tableta sadrži 100 mg raltegravira (u obliku raltegravirkalija).
English: Week 48 and Week 240 outcomes for patients on the recommended dose of raltegravir 400 mg twice daily from STARTMRK are shown in Table 3.
Croatian: U Tablici 3 prikazani su ishodi (48. i 240. tjedna) liječenja bolesnika koji su primali preporučenu dozu raltegravira 400 mg dvaput na dan u ispitivanju STARTMRK.
English: Do not switch between the chewable tablet, granules for oral suspension, 600 mg tablet or 400 mg tablet without first talking with your doctor, pharmacist or nurse.
Croatian: Nemojte prelaziti s tableta za žvakanje na granule za oralnu suspenziju, tablete od 600 mg ili tablete od 400 mg i obrnuto ako prethodno niste o tome razgovarali s liječnikom, ljekarnikom ili medicinskom sestrom.
English: No dose adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily) or maraviroc.
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan) ili maraviroka.
English: Each sachet contains 100 mg of raltegravir (as potassium).
Croatian: Jedna vrećica sadrži 100 mg raltegravira (u obliku raltegravirkalija).
English: Week 48 and Week 240 outcomes for patients on the recommended dose of raltegravir 400 mg twice daily from STARTMRK are shown in Table 5.
Croatian: U Tablici 5 prikazani su ishodi (48. i 240. tjedna) liječenja bolesnika koji su primali preporučenu dozu raltegravira 400 mg dvaput na dan u ispitivanju STARTMRK.
English: Non-Clade B
Croatian: Podtipovi virusa osim skupine B
English: No dose adjustment required for raltegravir (400 mg twice daily and 1,200 mg once daily) or methadone.
Croatian: Nije potrebno prilagođavati dozu raltegravira (400 mg dvaput na dan i 1200 mg jedanput na dan) ili metadona.
English: Isentress is also available in a 400 mg tablet, a chewable tablet and in granules for oral suspension.
Croatian: Isentress je dostupan i u obliku tableta od 400 mg, tableta za žvakanje te granula za oralnu suspenziju.
English: Isentress 600 mg film-coated tablets raltegravir
Croatian: ISENTRESS 600 mg filmom obložene tablete raltegravir
English: ISENTRESS 600 mg film-coated tablets raltegravir
Croatian: Isentress 600 mg filmom obložene tablete raltegravir
English: EXPIRY DATE
Croatian: Ispitivanje STARTMRK
English: ISENTRESS 400 mg film-coated tablets raltegravir
Croatian: Isentress 400 mg filmom obložene tablete raltegravir
English: - Hydroxypropyl cellulose - Sucralose - Mannitol - Monoammonium glycyrrhizinate - Sorbitol (E420) - Fructose - Banana flavour - Sucrose - Crospovidone, Type A - Magnesium stearate - Hypromellose 2910/6cP - Macrogol/PEG 400 - Ethylcellulose 20 cP - Ammonium hydroxide - Medium chain triglycerides - Oleic acid - Microcrystalline cellulose - Carmellose sodium
Croatian: A - magnezijev stearat - hipromeloza 2910/6cP - makrogol/PEG 400 - etilceluloza 20 cP - amonijev hidroksid - trigliceridi srednje duljine lanca - oleatna kiselina - mikrokristalična celuloza - umrežena karmelozanatrij
English: ISENTRESS is also available in a 400 mg tablet and as granules for oral suspension for use.
Croatian: ISENTRESS je dostupan i u obliku tablete od 400 mg te u obliku granula za oralnu suspenziju.
English: Recommendations concerning co-administration tipranavir /ritonavir (raltegravir 400 mg Twice Daily)
Croatian: Preporuke za istodobnu primjenu etravirin (raltegravir 400 mg dvaput na dan)
English: Renal and urinary disorders Uncommon renal failure, nephritis, nephrolithiasis, nocturia, renal cyst, renal impairment, tubulointerstitial nephritis
Croatian: Poremećaji bubrega i mokraćnog sustava manje često zatajenje bubrega, nefritis, nefrolitijaza, nikturija, bubrežna cista, oštećenje funkcije bubrega, tubulointersticijski nefritis
English: No renal impairment study was conducted with raltegravir 1,200 mg once daily however, based on results with the 400 mg twice daily tablet, no clinically meaningful effect is anticipated.
Croatian: Međutim, s obzirom na rezultate kod primjene tablete od 400 mg dvaput na dan ne očekuje se klinički značajan učinak.
English: Clean up
Croatian: • smanjen tek
English: Uncommon skin papilloma
Croatian: manje često kožni papilomi
English: Check your prescription
Croatian: 8. korak: Provjerite propisanu dozu
English: Tell your doctor, pharmacist or nurse immediately if you notice any symptoms of infection, such as fever, and/or feeling unwell.
Croatian: Primijetite li bilo koji simptom infekcije, primjerice vrućicu i/ili opće loše osjećanje, odmah o tome obavijestite svog liječnika, ljekarnika ili medicinsku sestru.
English: 11 to less than 25 kg Chewable tablet
Croatian: od 11 do manje od 25 kg tableta za žvakanje doziranje na temelju tjelesne težine, vidjeti tablice za doziranje tableta za žvakanje 13
English: Measure Isentress
Croatian: 10. korak: Odmjerite Isentress
English: Co-administration of raltegravir 1,200 mg once daily with tipranavir/ritonavir could result in decreased raltegravir trough plasma levels; therefore, co-administration is not recommended (see section 4.5).
Croatian: Istodobna primjena raltegravira u dozi od 1200 mg jedanput na dan s tipranavirom/ritonavirom može sniziti najniže koncentracije raltegravira u plazmi.
English: 3 syringes
Croatian: 4.8 Nuspojave
English: 1.5 x 100 mg † twice daily
Croatian: 1,5 x 100 mg † dvaput na dan od 28 do manje od 40
English: In drug interaction studies, efavirenz did not have a clinically meaningful effect on the pharmacokinetics of raltegravir 1,200 mg once daily; therefore, other less potent inducers (e.g., efavirenz, nevirapine, rifabutin, glucocorticoids, St. John's wort, pioglitazone) may be used with the recommended dose of raltegravir.
Croatian: Stoga se drugi manje snažni induktori (npr. efavirenz, nevirapin, rifabutin, glukokortikoidi, gospina trava, pioglitazon) mogu primjenjivati s preporučenom dozom raltegravira.
English: Refer to the 400 mg tablet and granules for oral suspension SmPCs for additional dosing information.
Croatian: Za dodatne informacije o doziranju, pročitajte sažetke opisa svojstava lijeka za tablete od 400 mg i granule za oralnu suspenziju.
English: Raltegravir was administered without regard to food in the pivotal safety and efficacy studies in HIV-infected patients.
Croatian: U ključnim ispitivanjima sigurnosti i djelotvornosti bolesnici inficirani HIV-om uzimali su raltegravir bez obzira na hranu.
English: SUMMARY OF PRODUCT CHARACTERISTICS
Croatian: Početne karakteristike
English: 4 µg Conjugated to CRM197 carrier protein ~ 20 µg
Croatian: 4 μg konjugirani na CRM 197 proteinski nosač ~ 20 μg
English: 1 vial with 1 syringe and 2 needles
Croatian: 1 bočica s 1 štrcaljkom i 2 igle
English: Serotype 6B
Croatian: serotipa 6B
English: Strength Pharmaceutical Form
Croatian: Doza Farmacuetski oblik Put primjene
English: Streptococcus pneumoniae saccharide suspension of: Serotype 4 2 µg
Croatian: 1 * Svaka doza od 0.5 ml sadrži: suspenziju pneumokoknog polisaharida: serotipa 4
English: Serotype 18C 2 µg
Croatian: serotipa 18C
English: Serotype 9V 2 µg
Croatian: serotipa 9V
English: 5 x 10 pre-filled syringes l t o r
Croatian: 5 X 10 napunjenih štrcaljki