FrancophonIA/ELRC3.0 huggingface dataset:
English: Use of filgrastim for the mobilisation of PBPCs in normal donors prior to allogeneic PBPC transplantation
Croatian: Primjena filgrastima za mobilizaciju progenitorskih stanica periferne krvi u zdravih darivatelja prije transplantacije alogenih progenitorskih stanica periferne krv
English: The use of filgrastim-mobilised PBPCs has been shown to reduce the depth and duration of thrombocytopenia following myelosuppressive or myeloablative chemotherapy.
Croatian: Pokazalo se da primjena filgrastimom mobiliziranih progenitorskih stanica periferne krvi smanjuje jačinu i trajanje trombocitopenije nakon mijelosupresivne ili mijeloablativne kemoterapije.
English: Glomerulonephritis has been reported in patients receiving filgrastim and pegfilgrastim.
Croatian: U bolesnika koji primaju filgrastim i pegfilgrastim zabilježen je glomerulonefritis.
English: Telephone +420/257-888.111
Croatian: Česká republika STADA Pharma CZ s.r.o. Tel: +420/257-888.111
English: For infusions Grastofil should be diluted in 20 mL of 5% glucose solution (see section 6.6).
Croatian: Kada se daje infuzijom, Grastofil se treba razrijediti u 20 ml 5%-tne otopine glukoze (vidjeti dio 6.6).
English: In this leaflet
Croatian: U ovoj uputi:
English: Uncommon (≥ 1/1,000 to <
Croatian: Manje često (≥1/1000 i <1/100)
English: Special precautions in SCN patients
Croatian: Posebne mjere opreza u onkoloških bolesnika
English: Vascular disorders, including veno-occlusive disease and fluid volume disturbances, have been reported occasionally in patients undergoing high dose chemotherapy followed by transplantation.
Croatian: U bolesnika koji su prije transplantacije primali visoke doze kemoterapijskih lijekova povremeno su zabilježeni krvožilni poremećaji, uključujući venookluzivnu bolest i poremećaje volumena tekućine.
English: The safety and efficacy of Grastofil are similar in adults, children and adolescents receiving cytotoxic chemotherapy.
Croatian: Sigurnost i djelotvornost Grastofila u djece i adolescenata koji primaju citotoksičnu kemoterapiju slične su onima u odraslih.
English: Magyarország STADA Arzneimittel AG Telephone +49/6101.603.0
Croatian: Magyarország STADA Arzneimittel AG Tel.: +49/6101.603.0
English: Pulmonary adverse reactions, in particular interstitial lung disease, have been reported after G-CSF administration.
Croatian: Nakon primjene G-CSF-a zabilježene su plućne nuspojave, osobito intersticijska bolest pluća.
English: Unless your doctor directs you otherwise, you must stop breast-feeding if you use Grastofil.
Croatian: Ako uzimate Grastofil morate prestati dojiti, osim ako Vam liječnik nije savjetovao drugačije.
English: Consideration should be given to temporary discontinuation or dose reduction of filgrastim in patients with severe chronic neutropenia who develop thrombocytopenia (platelet count < 100 x 10
Croatian: U bolesnika s teškom kroničnom neutropenijom u kojih se razvije trombocitopenija (broj trombocita < 100 x 10
English: Telephone +421/2-5262.1933
Croatian: Slovenská republika STADA PHARMA Slovakia s.r.o. Tel: +421/2-5262.1933
English: STADA Arzneimittel AG Telephone +49/6101.603.0
Croatian: STADA Arzneimittel AG Tel +49/6101.603.0
English: Grastofil contains sodium
Croatian: Grastofil sadrži natrij
English: There was a low frequency (approximately 3%) of myelodysplastic syndromes (MDS) or leukaemia in clinical trial patients with SCN treated with filgrastim.
Croatian: U kliničkim je ispitivanjima kod bolesnika s teškom kroničnom neutropenijom liječenih filgrastimom postojala niska učestalost (približno 3%) mijelodisplastičnih sindroma (MDS) ili leukemije.
English: Glacial acetic acid Sodium hydroxide Sorbitol (E420) Polysorbate 80
Croatian: 6.1 Popis pomoćnih tvari ledena acetatna kiselina natrijev hidroksid sorbitol (E420) polisorbat 80 voda za injekcije
English: Grastofil 48 MU/0.5 mL solution for injection/infusion in pre-filled syringe filgrastim
Croatian: Grastofil 48 MU/0,5 ml otopina za injekciju/infuziju u napunjenoj štrcaljki filgrastim
English: • pain when passing urine (dysuria)
Croatian: • bol pri mokrenju (dizurija)
English: Proteinuria
Croatian: Zbrinjavanje
English: Patients with renal/hepatic impairment
Croatian: Bolesnici s oštećenjem funkcije bubrega/jetre
English: Telephone +43/1-367.85.85.0
Croatian: STADA Arzneimittel Gesellschaft m.b.H. Tel:+43/1-367.85.85.0
English: EU/1/13/877/003 1 prefilled syringe EU/1/13/877/004 5 prefilled syringes
Croatian: EU/1/13/877/003 1 napunjena štrcaljka EU/1/13/877/004 5 napunjenih štrcaljki
English: Hypersensitivity, including anaphylactic reactions, occurring on initial or subsequent treatment have been reported in patients treated with filgrastim.
Croatian: Kod bolesnika liječenih filgrastimom prijavljena je preosjetljivost, uključujući anafilaktičke reakcije, koje su se javile kod prvog ili sljedećeg liječenja.
English: Special precautions in sickle cell trait and sickle cell disease Sickle cell crises, in some cases fatal, have been reported with the use of filgrastim in patients with sickle cell trait or sickle cell disease.
Croatian: Posebne mjere opreza kod nasljednog obilježja srpastih stanica i anemije srpastih stanica Uz primjenu filgrastima u bolesnika s nasljednim obilježjem srpastih stanica ili anemijom srpastih stanica zabilježena je kriza srpastih stanica, u nekim slučajevima sa smrtnim ishodom.
English: CLONMEL Healthcare Ltd. Telephone +353/52.61.77.777
Croatian: Tel:+ 353/52.61.77.777
English: Grastofil 30 MU/0.5 mL solution for injection/infusion in pre-filled syringe filgrastim
Croatian: Grastofil 30 MU/0,5 ml otopina za injekciju/infuziju u napunjenoj štrcaljki filgrastim
English: Acute respiratory distress syndrome a mediastinal disorders
Croatian: Krvožilni poremećaji hipertenzija hipotenzija venookluzivna bolestd stanje povećane kapilarne propusnostia aortitis
English: Cases of Sweets syndrome (acute febrile neutrophilic dermatosis) have been reported in patients treated with filgrastim.
Croatian: U bolesnika liječenih filgrastimom zabilježeni su slučajevi Sweetsovog sindroma (akutne febrilne neutrofilne dermatoze).
English: Hyperuricaemia
Croatian: • omaglica
English: International Retrospective Study (2006)
Croatian: Međunarodno retrospektivno ispitivanje b
English: EU/1/13/877/001 1 prefilled syringe EU/1/13/877/002 5 prefilled syringes
Croatian: EU/1/13/877/001 1 napunjena štrcaljka EU/1/13/877/002 5 napunjenih štrcaljki
English: For the mobilisation of PBPCs in normal donors prior to allogeneic PBPC transplantation
Croatian: Za mobilizaciju progenitorskih stanica periferne krvi u zdravih darivatelja prije transplantacije alogenih progenitorskih stanica periferne krvi
English: Grastofil 48 MU/0.5 mL solution for injection/infusion in pre-filled syringe
Croatian: Grastofil 48 MU/0,5 ml otopina za injekciju/infuziju u napunjenoj štrcaljki
English: Then, if ANC remains > 1.0 x 10
Croatian: Zatim, ako ABN ostane > 1,0 x 109/l tijekom još 3 uzastopna dana
English: Injury, poisoning and procedural complications
Croatian: Ozljede, trovanja i proceduralne komplikacije transfuzijska reakcijae aVidjeti dio:
English: 9/L for 3 consecutive days
Croatian: ABN > 1,0 x 109/l tijekom 3 uzastopna dana
English: Grastofil 30 MU/0.5 mL solution for injection/infusion in pre-filled syringe
Croatian: Grastofil 30 MU/0,5 ml otopina za injekciju/infuziju u napunjenoj štrcaljki
English: Hepatomegaly
Croatian: Leukocitoza
English: Cutaneous vasculitis has been reported in patients treated with filgrastim.
Croatian: U bolesnika liječenih filgrastimom zabilježen je kožni vaskulitis.
English: In patients with severe chronic neutropenia (SCN)
Croatian: Bolesnici s teškom kroničnom neutropenijom Doziranje
English: Includes bone pain, back pain, arthralgia, myalgia, pain in extremity, musculoskeletal pain, musculoskeletal chest pain, neck pain d
Croatian: Poremećaji kože i potkožnog tkiva alopecija a osip a eritem makulopapularni osip kožni vaskulitis a
English: The cells are collected using a process called apheresis (ay-fer-ree-sis).
Croatian: Te se stanice prikupljaju postupkom koji se naziva afereza.
English: Grastofil for PBPC mobilisation after myelosuppressive chemotherapy
Croatian: Kada se Grastofil primjenjuje za mobilizaciju progenitorskih stanica periferne krvi nakon mijelosupresivne kemoterapije
English: PRE-FILLED SYRINGE
Croatian: Kožni vaskulitis
English: Česká republika STADA Pharma CZ s.r.o.
Croatian: Deutschland STADAPHARM GmbH Tel.
English: Kidney injury has been seen in patients who received filgrastim.
Croatian: U bolesnika koji primaju filgrastim opaženo je oštećenje bubrega.
English: Your doctor may regularly test your urine if you experience this side effect or if protein is found in your urine (proteinuria).
Croatian: Ako dobijete ovu nuspojavu ili se pronađu bjelančevine u mokraći (proteinurija), liječnik Vam može redovito raditi pretrage mokraće.
English: Blood alkaline phosphatase increased
Croatian: Poremećaji jetre i žuči hepatomegalija povišena alkalna fosfataza u krvi povišena aspartat aminotransferaza povišena gamaglutamil transferaza
English: Medicinal products such as melphalan, carmustine (BCNU) and carboplatin, when administered over prolonged periods prior to attempts at progenitor mobilisation, may reduce progenitor yield.
Croatian: Lijekovi poput melfalana, karmustina (BCNU) i karboplatine,
English: Respiratory, thoracic and
Croatian: Učinak kemoterapije na eritrocite i trombocite
English: Upper respiratory tract infection
Croatian: Infekcije i infestacije sepsa bronhitis infekcija gornjih dišnih putova infekcija mokraćnog sustava
English: Thrombocytopenia has been reported in patients receiving filgrastim.
Croatian: U bolesnika koji primaju filgrastim zabilježena je trombocitopenija.
English: which are known to decrease the heart rate
Croatian: NAVOĐENJE DJELATNE(IH) TVARI
English: • wearing appropriate protective clothing.
Croatian: • nositi prikladnu zaštitnu odjeću.
English: Take tablet(s) at the same time every day.
Croatian: Uzmite tabletu(e) svaki dan u isto vrijeme.
English: These could be serious and possibly even life-threatening.
Croatian: To bi moglo biti ozbiljno i možda čak opasno po život.
English: Mayzent is taken once daily.
Croatian: Mayzent se uzima jedanput na dan.
English: It must be repeated at suitable intervals.
Croatian: Mora se ponavljati u odgovarajućim intervalima.
English: You will have to restart at day 1.
Croatian: Morat ćete ponovno početi od 1. dana.
English: Characteristics in specific groups or special populations
Croatian: Karakteristike u specifičnim skupinama ili specijalnim populacijama
English: • if you have high blood pressure that cannot be controlled by medicines.
Croatian: • ako imate visoki krvni tlak koji se ne može kontrolirati lijekovima.
English: Do not give this medicine to children and adolescents below 18 years of age because it has not yet been studied in this age group.
Croatian: Nemojte davati ovaj lijek djeci i adolescentima mlađima od 18 godina jer on još nije bio ispitivan u toj dobnoj skupini.
English: Ask your doctor about reliable methods of contraception.
Croatian: Pitajte svog liječnika koje su pouzdane metode kontracepcije.
English: • pain in hands or feet
Croatian: • bol u rukama ili nogama
English: The safety and efficacy of siponimod in children and adolescents aged 0 to 18 years have not yet been established.
Croatian: Sigurnost i djelotvornost siponimoda u djece i adolescenata u dobi od 0 do 18 godina nisu još ustanovljene.
English: Some side effects could be serious
Croatian: Neke bi nuspojave mogle biti ozbiljne
English: • Other reminders:
Croatian: • Ostali podsjetnici:
English: - if you have an active cancer.
Croatian: - ako imate aktivni rak.
English: Specific measures are also included in the Physician Education Pack.
Croatian: Specifične mjere su također uključene u edukacijski paket za liječnika.
English: Mayzent will stay in your body for up to 10 days after you stop taking it.
Croatian: Mayzent će ostati u Vašem tijelu do 10 dana nakon što ga prestanete uzimati.
English: In both species, prenatal mortality was increased.
Croatian: U obje je vrste bio povećan prenatalni mortalitet.
English: Missed dose after day 6
Croatian: Propuštena doza nakon 6. dana
English: • What multiple sclerosis is.
Croatian: • Što je multipla skleroza.
English: New onset third-degree AV block occurring at any time b.
Croatian: Novonastali AV blok trećeg stupnja koji se pojavi u bilo kojem trenutku b.
English: Tests before and during treatment
Croatian: Pretrage prije i tijekom liječenja
English: • Reproductive toxicity:
Croatian: • Reproduktivna toksičnost:
English: Your doctor will advise you on this (see “Other medicines and Mayzent”).
Croatian: Vaš će Vas liječnik savjetovati u vezi toga (vidjeti „Drugi lijekovi i Mayzent“).
English: Post-dose declines on the following days are less pronounced.
Croatian: Smanjenja nakon doze u narednim danima manje su izražena.
English: How quickly this medicine is broken down (metabolised) in the body varies from patient to patient and different people therefore require different doses.
Croatian: Koliko brzo se ovaj lijek razgrađuje (metabolizira) u tijelu varira od bolesnika do bolesnika pa različitim ljudima stoga trebaju različite doze.
English: • Mayzent is not recommended in:
Croatian: • Mayzent se ne preporučuje u:
English: You should limit your exposure to the sun and UV rays by:
Croatian: Trebate ograničiti svoju izloženost suncu i UV zrakama tako što ćete:
English: Elderly patients (65 years of age and above)
Croatian: Stariji bolesnici (u dobi od 65 i više godina)
English: Additional exposure of 0.25 mg on day 5 does not compromise patient safety.
Croatian: Dodatna izloženost od 0,25 mg 5. dana ne ugrožava sigurnost bolesnika.
English: 78% of patients had been previously treated with a therapy for their MS.
Croatian: Ukupno 78% bolesnika prethodno se liječilo terapijom za svoj MS.
English: Siponimod is taken with or without food.
Croatian: Siponimod se uzima s hranom ili bez nje nje.
English: Follow the instructions on the pack (see also the “Titration pack” table).
Croatian: Slijedite upute na pakiranju (vidjeti i tablicu „Pakiranje za titraciju“).
English: This may increase your risk of developing skin cancer.
Croatian: To može kod Vas povećati rizik od razvoja raka kože.
English: On day 6, you will switch to your regular treatment dose.
Croatian: 6. dana ćete prijeći na Vašu redovitu dozu liječenja.
English: Average over month 12 and month 24
Croatian: Prosjek tijekom 12. i 24. mjeseca
English: Estimated CL/F (L/h)
Croatian: Procijenjeni CL/F (L/h)
English: Unexpected neurological or psychiatric symptoms/signs
Croatian: Neočekivani neurološki ili psihijatrijski simptomi/znakovi
English: Such events have not been reported for siponimod in the development programme.
Croatian: Takvi događaji nisu bili prijavljeni za siponimod u programu razvoja.
English: Talk to your doctor if you have any concerns.
Croatian: Obratite se svom liječniku ako ste oko bilo čega zabrinuti.
English: Make sure to tell your doctor if you are taking or receiving any of the following medicines or therapies:
Croatian: Svakako obavijestite svog liječnika ako uzimate ili dobivate bilo koji od sljedećih lijekova ili terapija:
English: • if you think your MS is getting worse or if you notice any new or unusual symptoms.
Croatian: • ako mislite da se Vaša multipla skleroza (MS) pogoršava ili ako primijetite bilo kakve nove ili neuobičajene simptome.
English: Bradycardia Atrioventricular block (first and second degree)
Croatian: Bradikardija Atrioventrikularni blok (prvog i drugog stupnja)
English: There is no experience with Mayzent in elderly patients.
Croatian: Nema iskustva s Mayzentom u starijih bolesnika.
English: Take the tablet with water.
Croatian: Uzmite tabletu s vodom.
English: Patients who experienced bradycardia were generally asymptomatic.
Croatian: Bolesnici koji su imali bradikardiju općenito su bili asimptomatski.
English: If you miss a dose when you are on the regular treatment dose (day 7 onwards), take it as soon as you remember.
Croatian: Ako propustite dozu kada ste na redovitoj dozi liječenja (7. dan i nadalje), uzmite je čim se sjetite.
English: Race/Ethnicity
Croatian: Rasa/etničko podrijetlo
English: Unchanged siponimod was not detected in urine.
Croatian: Nepromijenjeni siponimod nije bio pronađen u urinu.
English: • regularly applying sunscreen with a high degree of UV protection.
Croatian: • redovito nanositi kremu za sunčanje s visokim stupnjem UV zaštite.
English: Your doctor will tell you whether your illness allows you to drive vehicles and use machines safely.
Croatian: Liječnik će Vam reći dopušta li Vam bolest da sigurno upravljate vozilima i strojevima.
English: If you take more Mayzent than you should
Croatian: Ako uzmete više Mayzenta nego što ste trebali
English: The film-coated tablets should be swallowed whole with water.
Croatian: Filmom obložene tablete treba progutati cijele s vodom.
English: Interference with haematological testing
Croatian: Interferencija s hematološkim testiranjem
English: The majority of cases occurred within the first 3-4 months of therapy.
Croatian: Većina slučajeva dogodila se u prva 3-4 mjeseca terapije.
English: • if you have severe breathing problems when sleeping (sleep apnoea).
Croatian: • ako imate teških problema s disanjem u snu (apneja u snu).
English: Your doctor will advise you on this.
Croatian: Vaš liječnik će Vas savjetovati o ovome.
English: • Doctors will provide counselling in the event of pregnancy and evaluation of the outcome of any pregnancy.
Croatian: • Liječnici će pružiti savjetovanje u slučaju trudnoće i procjenu ishoda bilo koje trudnoće.
English: Study duration was variable for individual patients (median study duration was 21 months, range: 1 day to 37 months).
Croatian: Trajanje ispitivanja bilo je različito za pojedinačne bolesnike (medijan trajanja ispitivanja bio je 21 mjesec, raspon: 1 dan do 37 mjeseci).
English: The siponimod fraction found in plasma is 68% in humans.
Croatian: Frakcija siponimoda koja se nalazi u plazmi je 68% u ljudi.
English: - if blood tests show that your body cannot break down this medicine well enough, you should not take it (see “Blood tests before and during treatment” below).
Croatian: - ako krvne pretrage pokazuju da Vaše tijelo ne može dovoljno dobro razgrađivati ovaj lijek, ne biste ga smjeli uzimati (vidjeti dio „Krvne pretrage prije i tijekom liječenja“ u nastavku).
English: Information that the monitoring may need to extend overnight, if the patient experiences symptoms during the first 6 hours.
Croatian: Informacija da će praćenje možda trebati produžiti preko noći, ako bolesnik iskusi simptome tijekom prvih 6 sati.
English: Talk to your doctor before taking Mayzent:
Croatian: Obratite se svom liječniku prije nego uzmete Mayzent:
English: Risk of infections
Croatian: Rizik od infekcija
English: • if you have an infection.
Croatian: • ako imate infekciju.
English: Prior to launch of Mayzent in each Member State the Marketing Authorisation Holder (MAH) must agree about the content and format of the educational programme, including communication media, distribution modalities, and any other aspects of the programme, with the National Competent Authority (NCA).
Croatian: Prije stavljanja Mayzenta u promet u svakog državi članici nositelj odobrenja mora usuglasiti sadržaj i format edukacijskog programa, uključujući komunikacijske medije, načine distribucije i sve druge aspekte programa s nacionalnim nadležnim tijelom.
English: At the start of treatment you may occasionally feel dizzy.
Croatian: Na početku liječenja možda ćete povremeno osjećati omaglicu.
English: Up to month 24
Croatian: Do 24. mjeseca
English: You will be given a titration pack, with which your dose will be gradually increased over 5 days.
Croatian: Dobit ćete pakiranje za titraciju, uz koje će se Vaša doza postupno povećavati tijekom 5 dana.
English: Study A2304 (EXPAND) in SPMS
Croatian: Ispitivanje A2304 (EXPAND) za SPMS
English: If this applies to you, note that it is nevertheless safe for you to take five 0.25 mg tablets on day 5 of the titration period as indicated above.
Croatian: Ako se to odnosi na Vas, imajte na umu da je svejedno sigurno da uzmete pet tableta od po 0,25 mg na 5. dan razdoblja titracije kako je gore navedeno.
English: • Patient/Caregiver Guide to be provided to all patients;
Croatian: • Vodič za bolesnika/skrbnika koji će se dati svim bolesnicima;
English: In the phase III clinical study, 1% of all discontinuations met one of these criteria.
Croatian: U kliničkom ispitivanju faze III, 1% svih trajnih prekida liječenja ispunjavao je jedan od ovih kriterija.
English: • Due to the potential teratogenic risk of siponimod women of childbearing potential should:
Croatian: • Zbog potencijalnog teratogenog rizika siponimoda, žene reproduktivne dobi trebaju:
English: You may not feel anything or you may feel dizzy or tired.
Croatian: Možda nećete ništa osjećati ili biste mogli osjećati omaglicu ili umor.
English: Your doctor may ask you to stop taking these to avoid an increased effect on the immune system.
Croatian: Liječnik Vas može zamoliti da prestanete uzimati te lijekove kako bi se izbjegao povećani učinak na imunološki sustav.
English: Clinical evaluations were performed at screening and every 3 months and at the time of relapse.
Croatian: Kliničke evaluacije obavljene su na probiru te svaka 3 mjeseca i u vrijeme relapsa.
English: • Infections, including varicella zoster reactivation, reactivation of the other viral infections, PML and other rare opportunistic infections:
Croatian: • Infekcije, uključujući reaktivaciju varicella zoster virusa, reaktivaciju drugih virusnih infekcija, PML i druge rijetke oportunističke infekcije:
English: Both are single nucleotide polymorphisms.
Croatian: Oba su polimorfizmi jednog nukleotida.
English: Fertility and reproductive toxicity
Croatian: Plodnost i reproduktivna toksičnost
English: UV therapy during Mayzent treatment may increase your risk of developing skin cancer.
Croatian: UV terapija tijekom liječenja Mayzentom može povećati rizik od razvoja raka kože.
English: Siponimod readily crosses the blood-brain barrier.
Croatian: Siponimod lako prelazi krvno-moždanu barijeru.
English: • Bradyarrhythmia (including conduction defects) during treatment initiation:
Croatian: • Bradiaritmija (uključujući smetnje provođenja) tijekom početka liječenja:
English: If you need to have a vaccination, talk to your doctor first.
Croatian: Ako morate primiti cjepivo, razgovarajte najprije sa svojim liječnikom.
English: - Active malignancies.
Croatian: - Aktivne zloćudne bolesti.
English: Mayzent is not expected to affect your ability to drive and use machines when you are on your regular treatment dose.
Croatian: Ne očekuje se da bi Mayzent mogao utjecati na Vašu sposobnost upravljanja vozilima i strojevima kada ste na redovitoj dozi liječenja.
English: The side effects described in this leaflet may still occur during this period (see “Possible side effects” in section 4).
Croatian: Nuspojave opisane u ovoj uputi mogu se i dalje javljati tijekom ovog razdoblja (vidjeti „Moguće nuspojave“ u dijelu 4).
English: Other side effects include those listed below.
Croatian: Druge nuspojave uključuju one navedene u nastavku.
English: Due to the high plasma protein binding (>99.9%) of siponimod, haemodialysis is not expected to alter the total and unbound siponimod concentration and no dose adjustments are anticipated based on these considerations.
Croatian: Zbog visokog stupnja vezanja siponimoda za proteine u plazmi (>99,9%), ne očekuje se da će hemodijaliza promijeniti koncentraciju ukupnog i nevezanog siponimoda i nisu predviđene prilagodbe doze na temelju ovih razmatranja.
English: Do not use this medicine if you notice that the pack is damaged or shows signs of tampering.
Croatian: Ovaj se lijek ne smije upotrijebiti ako primijetite da je pakiranje oštećeno ili su vidljivi znakovi otvaranja.
English: If you are taking a beta blocker, such as atenolol or propranolol, your doctor may ask you to temporarily stop your beta-blocker treatment until you have reached your full daily dose of Mayzent.
Croatian: Ako uzimate beta blokator, poput atenolola ili propranolola, liječnik Vas može reći da privremeno prekinete liječenje beta blokatorom dok ne dosegnete Vašu punu dnevnu dozu Mayzenta.