FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients with mild to moderate renal insufficiency (creatinine clearance from 45 to 79 ml/min) should avoid taking non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, and acetylsalicylic acid (>1.3 g daily) for 2 days before, on the day of, and 2 days following pemetrexed administration (see section 4.5).
Danish: Patienter med let til moderat nyreinsufficiens (kreatininclearance på 45-79 ml/min) skal undgå at tage non-steroide anti-inflammatoriske lægemidler (NSAID-præparater) såsom ibuprofen og acetylsalicylsyre (>1,3 g daglig) i 2 dage før, på dagen for og i 2 dage efter indgift af pemetrexed (se pkt.
English: Pemetrexed was not mutagenic in either the in vitro chromosome aberration test in Chinese hamster ovary cells, or the Ames test. Pemetrexed has been shown to be clastogenic in the in vivo micronucleus test in the mouse.
Danish: Pemetrexed var hverken mutagent i in vitro-testen for kromosomafvigelse hos kinesiske hamstere eller i Ames-testen.
English: A multi-centre, randomised, double-blind, placebo-controlled Phase-3 study (JMEN), compared the efficacy and safety of maintenance treatment with pemetrexed plus best supportive care (BSC) (N = 441) with that of placebo plus BSC (N = 222) in patients with locally advanced (Stage IIIB) or metastatic (Stage IV) Non-Small Cell Lung Cancer (NSCLC) who did not progress after 4 cycles of first-line doublet therapy containing cisplatin or carboplatin in combination with gemcitabine, paclitaxel, or docetaxel.
Danish: Et randomiseret, dobbeltblindt, placebokontrolleret fase 3-multicenterstudie (JMEN) sammenlignede virkning og sikkerhed af vedligeholdelsesbehandling med pemetrexed plus bedste understøttende pleje (BSC) (N = 441) med placebo plus BSC (N = 222) hos patienter med lokalt fremskreden (trin IIIB) eller metastatisk (trin IV) ikke-småcellet lungecancer (NSCLC), som ikke fik bedring efter 4 serier med 1. linje-dubletbehandling bestående af cisplatin eller carboplatin sammen med gemcitabin, paclitaxel eller docetaxel.
English: What Pemetrexed Pfizer contains
Danish: Pemetrexed Pfizer indeholder:
English: Abbreviations: ALT = alanine aminotransferase; AST = aspartate aminotransferase; CTCAE = Common Terminology Criteria for Adverse Event; NCI = National Cancer Institute; SGOT = serum glutamic oxaloacetic aminotransferase; SGPT = serum glutamic pyruvic aminotransferase.
Danish: Nyrer og urinveje Almindelig Nyresygdomme**** 7,6 0,9 1,7 0,0 Forkortelser: ALAT = alaninaminotransferase; ASAT = aspartataminotransferase; CTCAE = Common Terminology Criteria for Adverse Event; NCI = National Cancer Institute.
English: The table below provides the frequency and severity of undesirable effects that have been reported in > 5% of 265 patients randomly assigned to receive single-agent pemetrexed with folic acid and vitamin B12 supplementation, and 276 patients randomly assigned to receive single-agent docetaxel.
Danish: Nedenstående tabel viser hyppigheden og sværhedsgraden af bivirkninger, der blev rapporteret hos > 5 % af 265 patienter, som var randomiseret til enkeltstofbehandling med pemetrexed og tilskud af folsyre og B12-vitamin, og 276 patienter, som var randomiseret til enkeltstofbehandling med docetaxel.
English: Sexually mature males are advised not to father a child during the treatment and up to 6 months thereafter.
Danish: Det frarådes, at kønsmodne mænd gør en kvinde gravid under behandlingen og i op til 6 måneder efter behandlingen.
English: An analysis of the impact of NSCLC histology on the treatment effect on overall survival was in favour of pemetrexed versus docetaxel for other than predominantly squamous histologies (N = 399, 9.3 versus 8.0 months, (HR) = 0.78; 95% CI = 0.61-1.00, p = 0.047) and was in favour of docetaxel for squamous cell carcinoma histology (N =172, 6.2 versus 7.4 months, adjusted HR = 1.56; 95% CI = 1.08-2.26, p = 0.018).
Danish: En analyse af virkningen på NSCLCs histologi for behandlingens virkning på overlevelse var til fordel for pemetrexed versus docetaxel bortset fra cancerformer hovedsageligt bestående af pladeepitelceller (n=399; 9,3 versus 8,0 måneder, HR= 0,78; 95 % CI= 0,61-1,00; p= 0,047) og til fordel for docetaxel for carcinom af pladeepitelceller (n= 172; 6,2 versus 7,4 måneder, justeret HR = 1,56; 95 % CI= 1,08-2,26; p= 0,018).
English: EMPHACIS, a multi-centre, randomised, single-blind Phase 3 study of pemetrexed plus cisplatin versus cisplatin in chemonaive patients with malignant pleural mesothelioma, has shown that patients treated with pemetrexed and cisplatin had a clinically meaningful 2.8-month median survival advantage over patients receiving cisplatin alone.
Danish: EMPHACIS, et randomiseret, enkeltblindet, fase 3-multicenterstudie med pemetrexed sammen med cisplatin versus cisplatin alene til patienter, der ikke tidligere havde fået kemoterapi, og som led af malignt pleuramesoteliom, viste, at de patienter, som blev behandlet med pemetrexed og cisplatin, havde en klinisk meningsfuld længere median-levetid på 2,8 måneder end patienter, som kun blev behandlet med cisplatin.
English: In the absence of data regarding potential interaction with NSAIDs having longer half-lives such as piroxicam or rofecoxib, the concomitant administration with pemetrexed in patients with mild to moderate renal insufficiency should be interrupted for at least 5 days prior to, on the day of, and at least 2 days following pemetrexed administration (see section 4.4).
Danish: Da der ikke foreligger data om potentielle interaktioner mellem pemetrexed og NSAID-præparater med længere halveringstid, såsom piroxicam og rofecoxib, skal behandling med disse afbrydes hos patienter med let til moderat nyreinsufficiens mindst 5 dage før, på behandlingsdagen og i mindst 2 dage efter indgift af pemetrexed (se pkt.
English: Parenteral medicinal products must be inspected visually for particulate matter and discolouration prior to administration.
Danish: Parenterale lægemidler bør kontrolleres visuelt for partikler og misfarvning før indgivelse.
English: 50% of previous dose (both pemetrexed and cisplatin) a These criteria meet the National Cancer Institute Common Toxicity Criteria (CTC v2.0; NCI 1998)
Danish: 50 % af tidligere dosis (både pemetrexed og cisplatin) Disse kriterier opfylder National Cancer Institute Common Toxicity Criteria (CTC v2.0; NCI 1998) definition på ≥CTC grad 2 blødning.
English: Clinically relevant CTC toxicities that were reported in < 1% of the patients that were randomly assigned to pemetrexed include supraventricular arrhythmias.
Danish: De klinisk relevante CTC-toksiciteter, som blev rapporteret hos < 1 % af de patienter, der var randomiseret til pemetrexed, omfattede supraventrikulær arytmi.
English: Median overall survival in months (95% CI)
Danish: Median overlevelse i måneder (95% CI)
English: Pemetrexed infusion solutions prepared as directed above are compatible with polyvinyl chlorideand polyolefin- lined administration sets and infusion bags.
Danish: Pemetrexedinfusionsopløsninger, der er forberedt som angivet ovenfor, er kompatible med indgivelsessæt og dropposer, som er belagt med polyvinylchlorid og polyolefin.
English: In clinical trials, cases of interstitial pneumonitis with respiratory insufficiency, sometimes fatal, have been reported uncommonly in patients treated with pemetrexed.
Danish: Tilfælde af pnemonia interstitialis med respiratorisk insufficiens, sommetider dødeligt, er ikke almindeligt rapporteret hos patienter behandlet med pemetrexed i kliniske studier.
English: Women of childbearing potential must use effective contraception during treatment with pemetrexed.
Danish: Kvinder i den fertile alder skal anvende effektiv kontraception under behandling med pemetrexed.
English: The median time from the start of pemetrexed plus cisplatin induction therapy to the start of maintenance treatment was 2.96 months on both the pemetrexed arm and the placebo arm. Randomised patients received maintenance treatment until disease progression.
Danish: Den mediane tid fra start af pemetrexed og cisplatin induktionsbehandling til start af vedligeholdelsesbehandling var 2,96 måneder i både pemetrexedog placeboarmen.
English: Pemetrexed Pfizer is also a treatment for patients with advanced stage of lung cancer whose disease has progressed after other initial chemotherapy has been used.
Danish: Pemetrexed Pfizer er også en behandling til patienter med fremskreden lungekræft, hvor sygdommen har udviklet sig, efter anden indledende behandling med kemoterapi har været forsøgt.
English: Rarely, immune-mediated haemolytic anaemia has been reported in patients treated with pemetrexed.
Danish: Der er rapporteret sjældne tilfælde af immunmedieret hæmolytisk anæmi hos patienter behandlet med pemetrexed.
English: Patients with hepatic impairment
Danish: Patienter med nedsat leverfunktion
English: Breast-feeding must be discontinued during pemetrexed treatment.
Danish: Amningen skal afbrydes under behandling med pemetrexed.
English: Time to treatment failure (months) (95% CI)
Danish: Tid til behandlingssvigt (måneder) (95 % - CI)
English: Pemetrexed Pfizer is also given in combination with cisplatin for the initial treatment of patients with advanced stage of lung cancer.
Danish: Pemetrexed Pfizer er også en behandling, som gives i kombination med cisplatin, som første behandling af patienter med fremskreden lungecancer.
English: Common ALT (SGPT) elevation
Danish: Almindelig ALAT-forhøjelse ASAT-forhøjelse
English: The following information is intended for healthcare professionals only: Instructions for use, handling and disposal
Danish: Følgende oplysninger er tiltænkt læger og sundhedspersonale:
English: Creatinine elevation Creatinine clearance decreased**
Danish: Nedsat kreatininclearance**
English: Following pemetrexed plus cisplatin induction (4 cycles), treatment with pemetrexed was statistically superior to placebo for OS (median 13.9 months versus 11.0 months, hazard ratio = 0.78, 95%CI=0.64-0.96, p=0.0195).
Danish: Efter induktionsbehandling med pemetrexed plus cisplatin (4 serier) var behandling med pemetrexed statistisk superior i forhold til placebo med hensyn til total overlevelse (median 13,9 måneder versus 11,0 måneder, hazard ratio = 0,78; 95 % CI=0,64-0,96; p=0,0195).
English: **According to National Cancer Institute CTC (v2.0; NCI 1998), alopecia should only be reported as Grade 1 or 2.
Danish: ** I henhold til National Cancer Institute CTC (v2.0; NCI 1998), bør alopeci kun rapporteres som grad 1 eller 2.
English: N = 863 0.94a
Danish: N=863 0,94
English: Unopened vial
Danish: Lever og galdeveje
English: Breast-feeding must be discontinued during pemetrexed therapy (see section 4.3).
Danish: Amning skal ophøre under behandling med pemetrexed (se pkt.
English: 100% of previous dose a National Cancer Institute Common Toxicity Criteria (CTC v2.0; NCI 1998) b Excluding neurotoxicity
Danish: National Cancer Institute Common Toxicity Criteria (CTC v 2.0; NCI 1998) Undtagen neurotoksicitet
English: Single use only SPECIAL WARNING THAT THE MEDICINAL PRODUCT MUST BE STORED OUT OF THE SIGHT AND REACH OF CHILDREN Keep out of the sight and reach of children.
Danish: SÆRLIG ADVARSEL OM, AT LÆGEMIDLET SKAL OPBEVARES UTILGÆNGELIGT FOR BØRN
English: Pemetrexed Pfizer is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy (see section
Danish: Pemetrexed Pfizer er indiceret som monoterapi til vedligeholdelsesbehandling af lokalt fremskreden eller metastatisk ikke-småcellet lungecancer, bortset fra cancer hovedsageligt bestående af pladeepitelceller, hos patienter, hvis sygdom ikke har vist progression umiddelbart efter platinbaseret kemoterapi (se pkt.
English: Common Dyspepsia
Danish: Forstoppelse Almindelig Dyspepsi
English: How to use Pemetrexed Pfizer
Danish: Sådan skal De bruge Pemetrexed Pfizer
English: Clinically relevant CTC toxicity that was reported in <1% of the patients that were randomly assigned to pemetrexed include: allergic reaction/hypersensitivity, erythema multiforme, supraventricular arrhythmia and pulmonary embolism.
Danish: De klinisk relevante CTC-toksiciteter, som blev rapporteret hos < 1 % af de patienter, som blev randomiseret til pemetrexed, omfatter: allergisk reaktion/overfølsomhed, erythema multiforme, supraventrikulær arytmi og lungeemboli.
English: 50% of previous dose a National Cancer Institute Common Toxicity Criteria (CTC v2.0; NCI 1998)
Danish: National Cancer Institute Common Toxicity Criteria (CTC v 2.0; NCI 1998)
English: In patients with mild to moderate renal insufficiency (creatinine clearance from 45 to 79 ml/min), the concomitant administration of pemetrexed with NSAIDs (e.g., ibuprofen) or acetylsalicylic acid at higher doses should be avoided for 2 days before, on the day of, and 2 days following pemetrexed administration (see section 4.4).
Danish: Hos patienter med let til moderat nyreinsufficiens (kreatininclearance 45-79 ml/min) bør samtidig administration af pemetrexed og NSAID-præparater (for eksempel ibuprofen) eller acetylsalicylsyre i højere doser undgås 2 dage inden, på behandlingsdagen og i 2 dage efter indgift af pemetrexed (se pkt.
English: In patients with mild to moderate renal insufficiency eligible for pemetrexed therapy, NSAIDs with long elimination half-lives should be interrupted for at least 5 days prior to, on the day of, and at least 2 days following pemetrexed administration (see section 4.5).
Danish: Hos patienter med let til moderat nyreinsufficiens, som er egnet til behandling med pemetrexed, skal behandling med NSAID-præparater med en lang halveringstid afbrydes mindst 5 dage før, på dagen for og i mindst 2 dage efter indgift af pemetrexed (se pkt.
English: Common Conjunctivitis
Danish: Almindelig Konjunctivitis
English: The independent review of patient scans confirmed the findings of the investigator assessment of PFS. For randomised patients, as measured from the start of pemetrexed plus cisplatin first-line induction treatment, the median investigator-assessed PFS was 6.9 months for the pemetrexed arm and 5.6 months for the placebo arm (hazard ratio = 0.59, 95% CI = 0.47-0.74).
Danish: Den uafhængige evaluering af patienternes skanninger bekræftede investigatorernes vurdering af PFS. Investigatorernes mediane PFS-vurdering for de randomiserede patienter var 6,9 måneder for pemetrexedarmen og 5,6 måneder for placeboarmen (hazard ratio = 0,59; 95 % CI = 0,47-0,74) målt fra start af pemetrexed og cisplatin førstelinje-induktionsbehandling.
English: In a study conducted in beagle dog by intravenous bolus injection for 9 months, testicular findings (degeneration/necrosis of the seminiferous epithelium) have been observed.
Danish: Der blev set en påvirkning af testiklerne (degenerering/nekrose af seminiferous epithelium) i et studie udført på beaglehunde, der fik intravenøse bolusinjektioner i 9
English: Frequency Event**
Danish: Hyppighed Bivirkning**
English: The study met its primary endpoint and showed a statistically significant improvement in PFS in the pemetrexed arm over the placebo arm (N = 472, independently reviewed population; median of 3.9 months and 2.6 months, respectively) (hazard ratio = 0.64, 95% CI = 0.51-0.81, p = 0.0002).
Danish: Studiets primære endepunkt blev mødt og viste en statistisk signifikant forbedring i PFS i pemetrexedarmen over for placebo (N = 472, uafhængigt evalueret population, median på henholdsvis 3,9 måneder og 2,6 måneder) (hazard ratio = 0,64; 95 % CI = 0,51-0,81; p = 0,0002).
English: Women of childbearing potential must use effective contraception during treatment with pemetrexed (see section 4.6).
Danish: Kvinder i den fødedygtige alder skal anvende effektive svangerskabsforebyggende midler under behandlingen med pemetrexed (se pkt.
English: Pemetrexed Pfizer 100 mg powder for concentrate for solution for infusion Pemetrexed Pfizer 500 mg powder for concentrate for solution for infusion Pemetrexed Pfizer 1,000 mg powder for concentrate for solution for infusion pemetrexed
Danish: Pemetrexed Pfizer 100 mg pulver til koncentrat til infusionsvæske, opløsning Pemetrexed Pfizer 500 mg pulver til koncentrat til infusionsvæske, opløsning Pemetrexed Pfizer 1.000 mg pulver til koncentrat til infusionsvæske, opløsning pemetrexed
English: Median time to tumour progression (months) (95% CI)
Danish: Median tid til tumorprogression (måneder) (95 % - CI)
English: The study met its primary endpoint and showed a statistically significant improvement in PFS in the pemetrexed arm over the placebo arm (N = 581, independently reviewed population; median of 4.0 months and 2.0 months, respectively) (hazard ratio = 0.60, 95% CI = 0.49-0.73, p < 0.00001).
Danish: Studiet mødte dets primære endepunkt og viste statistisk signifikant forbedring i PFS i pemetrexedarmen i forhold til placeboarmen (N=581, en uafhængig overvåget population, median på henholdsvis 4 måneder og 2 måneder) (hazard ratio = 0,60, 95 % CI = 0,49-0,73; p < 0,00001).
English: ***According to National Cancer Institute CTC (v2.0; NCI 1998), taste disturbance and alopecia should only be reported as Grade 1 or 2.
Danish: ***I henhold til National Cancer Institute CTC (v2.0; NCI 1998), smagsforstyrrelser og alopeci bør kun rapporteres som grad 1 eller 2.
English: median OS for the overall population (N = 663) was 13.4 months for the pemetrexed arm and 10.6 months for the placebo arm, hazard ratio = 0.79 (95% CI= 0.65-0.95, p = 0.01192).
Danish: Den mediane samlede overlevelse (OS) for den totale population (N = 663) var 13,4 måneder for pemetrexed-armen og 10,6 måneder for placeboarmen, hazard ratio = 0,79 (95 % CI = 0,65- 0,95; p =
English: Serious cardiovascular events, including myocardial infarction and cerebrovascular events have been uncommonly reported during clinical studies with pemetrexed, usually when given in combination with another cytotoxic agent.
Danish: Under kliniske studier med pemetrexed er der ikke almindeligt rapporteret om svære kardiovaskulære hændelser herunder myokardieinfarkt og cerebrovaskulære hændelser, sædvanligvis når pemetrexed gives i kombination med et andet cytotoksisk lægemiddelstof.
English: Progression-free survival (months)
Danish: 95 %-CI for HR p-værdifornon-inferioritet(HR) Progressionsfri overlevelse (måneder)
English: Overall response rate** 41.3% (95% CI)
Danish: Samlet responsrate** (95 % - CI)
English: Clinically relevant CTC toxicities that were reported in < 1% of the patients that were randomly assigned to receive cisplatin and pemetrexed include arrhythmia and motor neuropathy.
Danish: De klinisk relevante CTC-toksiciteter, som blev rapporteret hos < 1 % af de patienter, der var randomiseret til cisplatin og pemetrexed, omfattede arytmi og motorisk neuropati.
English: As a result, concomitant use of live attenuated vaccines is not recommended (see sections 4.3 and 4.5).
Danish: Som et resultat heraf frarådes samtidig indgift af levende svækkede vacciner (se pkt.
English: Low haemoglobin level (anaemia) Low platelet count
Danish: Lavthæmoglobinniveau(anæmi)
English: In both treatment arms, these chemonaive patients were fully supplemented with folic acid and vitamin B12.
Danish: I begge behandlingsarme fik disse patienter, som ikke tidligere havde været i kemoterapi, fuldt tilskud af folsyre og B12-vitamin.
English: Extravasation should be managed by local standard practice as with other non-vesicants.
Danish: Som med andre ikke-blæretrækkende stoffer skal eventuel ekstravasation håndteres i henhold til lokal standardpraksis.
English: Pemetrexed Pfizer 1,000mg vial:
Danish: Pemetrexed Pfizer 1.000 mg hætteglas:
English: Medicinal product subject to restricted medical prescription (see Annex I: Summary of Product Characteristics, 4.2)
Danish: Lægemidlet må kun udleveres efter ordination på en recept udstedt af en begrænset lægegruppe (se bilag I: Produktresumé, pkt.
English: pemetrexed/cisplatin
Danish: Hyppighed Bivirkning* pemetrexed/cisplatin cisplatin
English: Clinically relevant CTC toxicities that were reported in ≥ 1% and ≤ 5% of the patients that were randomly assigned to pemetrexed include: infection without neutropenia, febrile neutropenia, allergic reaction/hypersensitivity, increased creatinine, motor neuropathy, sensory neuropathy, erythema multiforme, and abdominal pain.
Danish: De klinisk relevante CTC-toksiciteter, som blev rapporteret hos ≥ 1 % og ≤ 5 % af de patienter, der var randomiseret til pemetrexed, omfattede: infektion uden neutropeni, febril neutropeni, allergisk reaktion/overfølsomhed, forhøjet kreatinin, motorisk neuropati, sensorisk neuropati, erythema multiforme og mavesmerter.
English: Clinically relevant toxicity that was reported in < 1% of the patients that were randomly assigned to receive cisplatin and pemetrexed include: GGT increase, chest pain, arrhythmia, and motor neuropathy.
Danish: Klinisk relevant toksicitet, som blev rapporteret hos <1 % af de patienter, som blev randomiseret til at få cisplatin og pemetrexed, omfattede: forhøjet GGT, brystsmerter, arytmier og motorisk neuropati.
English: For patients with NSCLC other than predominantly squamous cell histology (N = 430, independently reviewed population) median PFS was 4.4 months for the pemetrexed arm and 1.8 months for the placebo arm, hazard ratio = 0.47 (95% CI = 0.37-0.60, p = 0.00001).
Danish: For patienter med NSCLC bortset fra cancer hovedsageligt bestående af pladeepitelceller (N = 430, uafhængig overvåget population) var den mediane PFS 4,4 måneder for pemetrexed-armen og 1,8 måneder for placeboarmen, hazard ratio = 0,47, 95 % CI = 0,37-0,60; p=0,00001.
English: Common Neuropathysensory
Danish: Almindelig Sensorisk neuropati
English: Reconstituted and infusion solutions
Danish: Til intravenøs anvendelse efter rekonstitution og fortynding
English: Stomatitis
Danish: Udslæt
English: The recommended dose of pemetrexed is 500 mg/m2 of body surface area (BSA) administered as an intravenous infusion over 10 minutes on the first day of each 21-day cycle.
Danish: Pemetrexed i kombination med cisplatin Den anbefalede dosis af pemetrexed er 500 mg/m2 legemesoverflade indgivet som intravenøs infusion over 10 minutter på den første dag i hver 21-dages-serie.
English: Hair loss
Danish: Hårtab
English: Pancytopenia- combined low counts of white cells, red cells and platelets Radiation pneumonitis (scarring of the air sacs of the lung associated with radiation therapy) may occur in patients who are also treated with radiation either before, during or after their pemetrexed therapy.
Danish: Strålingspneumonitis (arvæv i de fineste bronkier samt alveolerne på grund af strålebehandling) kan opstå hos patienter, somogsåbehandles medstrålingenten før, underellerefterderes behandlingmed pemetrexed.
English: Patients in both study arms were fully supplemented with folic acid and vitamin B12.
Danish: Patienterne i begge behandlingsgrupper fik fuldstændigt dækkende tilskud af folsyre og cyanocobalamin (vitamin B12).
English: Rash Alopecia
Danish: Udslæt Alopeci
English: Clinically relevant CTC toxicity of any grade that was reported in ≥1% and ≤5% of the patients that were randomly assigned to pemetrexed include: febrile neutropenia, infection, decreased platelets, diarrhoea, constipation, alopecia, pruritus/itching, fever (in the absence of neutropenia), ocular surface disease (including conjunctivitis), increased lacrimation, dizziness and motor neuropathy.
Danish: De klinisk relevante CTC-toksiciteter af enhver grad, der blev rapporteret hos ≥ 1 % og ≤ 5 % af de patienter, som var randomiseret til pemetrexed, omfatter: febril neutropeni, infektion, nedsat antal blodplader, diarré, forstoppelse, alopeci, pruritus/kløe, feber (uden neutropeni), sygdom i øjets overflade (inklusive konjunktivitis), øget tåreflåd, svimmelhed og motorisk neuropati.
English: Pemetrexed Pfizer 100mg vial:
Danish: Pemetrexed Pfizer 100 mg hætteglas:
English: Pemetrexed Pfizer in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma.
Danish: Pemetrexed Pfizer er indiceret til behandling af kemoterapinaive patienter med inoperabelt malignt pleuramesoteliom i kombination med cisplatin.