FrancophonIA/ELRC3.0 huggingface dataset:
English: IntronA is a medicine that contains the active substance interferon alfa-2b.
Slovenian: IntronA je zdravilo, ki vsebuje zdravilno učinkovino interferon alfa-2b.
English: IntronA is used as an add-on to anticancer treatments;
Slovenian: Zdravilo IntronA se uporablja kot dodatek zdravilom proti raku;
English: The active substance in IntronA, interferon alfa-2b, belongs to the group ‘interferons'.
Slovenian: Zdravilna učinkovina zdravila IntronA, interferon alfa-2b, spada v skupino interferonov.
English: For the full list of all side effects reported with IntronA, see the Package Leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila IntronA, glejte navodilo za uporabo.
English: • chronic myelogenous leukaemia (CML, a cancer of the white blood cells) in adults.
Slovenian: • kronične mieloične levkemije (CML, druge vrste raka belih krvničk) pri odraslih.
English: For a list of all restrictions with IntronA, see the package leaflet.
Slovenian: Za celoten seznam omejitev za zdravilo IntronA glejte navodilo za uporabo.
English: How has IntronA been studied?
Slovenian: Kako je bilo zdravilo IntronA raziskano?
English: What is IntronA used for?
Slovenian: Za kaj se zdravilo IntronA uporablja?
English: • follicular lymphoma (a cancer of the lymph tissue).
Slovenian: • folikularnega limfoma (raka limfatičnega tkiva).
English: • hairy cell leukaemia (a cancer of the white blood cells);
Slovenian: • dlakastocelične levkemije (raka belih krvničk);
English: How does IntronA work?
Slovenian: Kako zdravilo IntronA deluje?
English: How is IntronA used?
Slovenian: Kako se zdravilo IntronA uporablja?
English: • multiple myeloma (a cancer of the bone marrow).
Slovenian: • multiplega mieloma (raka kostnega mozga).
English: What is IntronA?
Slovenian: Kaj je zdravilo IntronA?
English: This overview was last updated in 02-2018.
Slovenian: Pregled je bil nazadnje posodobljen 02-2018.
English: It should be used in combination with safer sex practices, such as use of condoms.
Slovenian: Uporabljati se mora v kombinaciji z varnejšimi spolnimi praksami, na primer uporabo kondomov.
English: Further information on Truvada can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Slovenian: Nadaljnje informacije za zdravilo Truvada so na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: What measures are being taken to ensure the safe and effective use of Truvada?
Slovenian: Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Truvada?
English: The European Commission granted a marketing authorisation valid throughout the European Union for Truvada on 21 February 2005.
Slovenian: Evropska komisija je dovoljenje za promet z zdravilom Truvada, veljavno po vsej Evropski uniji, izdala 21. februarja 2005.
English: This means that it is converted into tenofovir in the body.
Slovenian: To pomeni, da se v telesu pretvori v tenofovir.
English: Other information about Truvada
Slovenian: Druge informacije o zdravilu Truvada
English: An overview of Truvada and why it is authorised in the EU
Slovenian: Pregled zdravila Truvada in zakaj je odobreno v EU
English: Why is Truvada authorised in the EU?
Slovenian: Zakaj je bilo zdravilo Truvada odobreno v EU?
English: What benefits of Truvada have been shown in studies?
Slovenian: Kakšne koristi zdravila Truvada so se pokazale v študijah?
English: Truvada is available as tablets.
Slovenian: Zdravilo Truvada je na voljo v obliki tablet.
English: What is Truvada and what is it used for?
Slovenian: Kaj je zdravilo Truvada in za kaj se uporablja?
English: There is a risk that pre-exposure prophylaxis may encourage risky behaviour but one of the main studies found that participation in the study reduced risky behaviour.
Slovenian: Obstaja tveganje, da bi predekspozicijska profilaksa utegnila spodbujati tvegano vedenje, a v eni od glavnih študij so ugotovili, da je bilo zaradi sodelovanja v študiji to manjše.
English: What are the risks associated with Truvada?
Slovenian: Kakšna tveganja so povezana z zdravilom Truvada?
English: As for all medicines, data on the use of Truvada is continuously monitored.
Slovenian: Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila Truvada stalno spremljajo.
English: The level of protection depended on how well individuals stuck to taking their medicine.
Slovenian: Raven zaščite je bila odvisna od tega, kako dosledno so osebe jemale zdravilo.
English: Truvada (emtricitabine / tenofovir disoproxil)
Slovenian: Truvada (emtricitabin/dizoproksiltenofovirat)
English: Side effects reported with Truvada are carefully evaluated and any necessary action taken to protect patients.
Slovenian: Neželeni učinki, o katerih so poročali pri zdravilu Truvada, se skrbno ovrednotijo in po potrebi se sprejmejo ukrepi za zaščito bolnikov.
English: The Agency concluded that Truvada's benefits are greater than its risks and recommended that it be given marketing authorisation.
Slovenian: Agencija je zaključila, da so koristi zdravila Truvada večje od z njim povezanih tveganj, in priporočila, da se zanj izda dovoljenje za promet.
English: Around two-thirds of the patients achieved and maintained viral load below 50 copies/ml after 48 weeks.
Slovenian: Pri približno dveh tretjinah bolnikov je bilo po 48 tednih doseženo in vzdrževano virusno breme pod 50 kopij/ml.
English: The main measure of effectiveness was the number of adults who tested positive for HIV-1 infection.
Slovenian: Glavno merilo učinkovitosti je bilo število odraslih, pri katerih je bilo testiranje za okužbo z virusom HIV-1 pozitivno.
English: Truvada was more effective than placebo for preventing HIV-1 infection.
Slovenian: Zdravilo Truvada je bilo učinkovitejše od placeba pri preprečevanju okužbe z virusom HIV-1.
English: When the active substances emtricitabine or tenofovir are given separately, the most common side effects (seen in more than 1 patient in 10) also include hypophosphataemia (low levels of phosphates in the blood), headache, dizziness, vomiting, rash, weakness and raised blood levels of creatine kinase (an enzyme found in muscles).
Slovenian: Kadar se zdravilni učinkovini emtricitabin ali tenofovir dajeta ločeno, najpogostejši neželeni učinki (opaženi pri več kot 1 od 10 bolnikov) vključujejo tudi hipofosfatemijo (nizko raven fosfatov v krvi), glavobol, omotico, bruhanje, izpuščaj, oslabelost in povišane ravni kreatin kinaze v krvi (encima, ki se nahaja v mišicah).
English: If patients with HIV-1 infection need to stop taking emtricitabine or tenofovir, or need to take different doses, they will need to take medicines containing emtricitabine or tenofovir disoproxil separately.
Slovenian: Če morajo bolniki, okuženi z virusom HIV-1, prekiniti jemanje bodisi emtricitabina ali tenofovirja oziroma je treba njune odmerke spremeniti, bodo morali jemati zdravila, ki ločeno vsebujejo emtricitabin ali dizoproksiltenofovirat.
English: The second study involved over 4,700 heterosexual couples, each with one partner who did not have HIV-1 infection and the other who had the infection.
Slovenian: V drugo študijo je bilo vključenih 4 700 heteroseksualnih parov, v katerih je bil en partner okužen z virusom HIV-1, drugi pa ne.
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Truvada have also been included in the summary of product characteristics and the package leaflet.
Slovenian: Priporočila in previdnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Truvada upoštevati zdravstveni delavci in bolniki, so vključeni tudi v povzetek glavnih značilnosti zdravila in navodilo za uporabo.
English: The main measure of effectiveness was the proportion of patients whose HIV-1 level in the blood (viral load) had fallen below a defined level.
Slovenian: Glavno merilo učinkovitosti je bil delež bolnikov, pri katerih je raven virusa HIV-1 v krvi (virusno breme) padla pod določeno raven.
English: The recommended dose for treating or preventing HIV-1 infection is one tablet once a day, preferably taken with food.
Slovenian: Priporočeni odmerek za zdravljenje ali preprečevanje okužbe z virusom HIV-1 je ena tableta enkrat na dan, ki se po možnosti vzame s hrano.
English: Both active substances have been authorised in the European Union (EU) since the early 2000s: emtricitabine was authorised as Emtriva in 2003, and tenofovir disoproxil was authorised as Viread in
Slovenian: Obe zdravilni učinkovini imata dovoljenje za promet v Evropski uniji (EU) od začetka 21. stoletja: emtricitabin kot zdravilo Emtriva od leta 2003, dizoproksiltenofovirat pa kot zdravilo Viread od leta 2002.
English: In addition it may be used from the age of 12 in adolescents with HIV who are resistant to first-line treatments or who cannot take them because of side effects.
Slovenian: Poleg tega se lahko uporablja tudi pri mladostnikih, starejših od 12 let, ki so okuženi z virusom HIV in so odporni proti zdravilom prve izbire ali teh zaradi neželenih učinkov ne morejo jemati.
English: The European Medicines Agency noted that the benefit of Truvada for treating HIV-1 infection has only been shown in patients who have not taken HIV treatment before, but that the simplified dosing regimen offered by the combination tablet taken once a day may help patients to stick to their treatment.
Slovenian: Evropska agencija za zdravila je ugotovila, da so bile koristi zdravila Truvada za zdravljenje okužbe z virusom HIV-1 dokazane samo pri bolnikih, ki predhodno še niso bili zdravljeni zaradi okužbe z virusom HIV, vendar da lahko poenostavljen način odmerjanja z uporabo kombinirane tablete enkrat na dan bolnikom pomaga vztrajati pri zdravljenju.
English: Truvada's active substances, taken in combination with other antiviral medicines, reduced viral load in the majority of patients and were more effective than the comparator medicines.
Slovenian: Zdravilni učinkovini v zdravilu Truvada sta v kombinaciji z drugimi protivirusnimi zdravili znižali virusno breme pri večini bolnikov in sta bili učinkovitejši kot primerjalna zdravila.
English: Truvada does not cure HIV infection or AIDS, but it may hold off damage to the immune system and the development of infections and diseases associated with AIDS.
Slovenian: Zdravilo Truvada ne ozdravi okužbe z virusom HIV ali aidsa, lahko pa upočasni slabšanje imunskega sistema ter prepreči razvoj okužb in bolezni, povezanih z aidsom.
English: Two main studies have evaluated the addition of Truvada to standard preventative measures for preexposure prophylaxis.
Slovenian: V dveh glavnih študijah so ocenjevali dodajanje zdravila Truvada standardnim preprečevalnim ukrepom predekspozicijske profilakse.
English: For the treatment of HIV-1 infection, Truvada, taken in combination with at least one other HIV medicine, reduces the amount of HIV in the blood and keeps it at a low level.
Slovenian: Pri zdravljenju okužbe z virusom HIV-1 zdravilo Truvada v kombinaciji z vsaj še enim drugim zdravilom proti virusu HIV zniža količino virusa HIV v krvi in jo vzdržuje na nizki ravni.
English: Healthcare professionals will also receive a brochure and reminder card to hand out to individuals receiving Truvada for pre-exposure prophylaxis.
Slovenian: Zdravstveni delavci bodo prejeli tudi brošuro in opozorilno kartico, namenjeno posameznikom, ki jemljejo zdravilo Truvada za predekspozicijsko profilakso.
English: The effectiveness of Truvada in adolescents was supported by studies showing that emtricitabine or tenofovir disoproxil reduced viral load when given with other antivirals to HIV-infected patients aged from 12 to 18 years, as well as evidence that the active ingredients are distributed similarly in the bodies of adolescents to those of adults and so would be expected to act in the same way.
Slovenian: Podporni dokazi za učinkovitost zdravila Truvada pri mladostnikih so bili pridobljeni v študijah, v katerih so dokazali, da sta emtricitabin ali dizoproksiltenofovirat zmanjšala virusno breme, kadar sta bila uporabljena v kombinaciji z drugimi protivirusnimi zdravili pri bolnikih, okuženih z virusom HIV, ki so bili stari od 12 do 18 let, prav tako pa so bili zbrani dokazi, da se zdravilni učinkovini pri mladostnikih podobno porazdelita po telesu kot pri odraslih, iz česar izhaja sklep, da bosta tudi delovali na enak način.
English: The Agency also considered that the benefit of Truvada has been shown for pre-exposure prophylaxis but the level of protection depends on how well individuals stick to the recommended dose schedule.
Slovenian: Odbor je tudi menil, da so bile dokazane koristi zdravila Truvada za predekspozicijsko profilakso, da pa je raven zaščite odvisna od tega, kako dosledno oseba upošteva shemo priporočenih odmerkov.
English: Truvada contains two active substances, emtricitabine (200 mg) and tenofovir disoproxil (245 mg).
Slovenian: Zdravilo Truvada vsebuje dve zdravilni učinkovini, emtricitabin (200 mg) in dizoproksiltenofovirat (245 mg).
English: The company that markets Truvada will provide an information pack to doctors which covers the risk of reduced kidney function with Truvada in adults and children, and information about use in adults for pre-exposure prophylaxis.
Slovenian: Podjetje, ki trži zdravilo Truvada, bo pripravilo informacijski komplet za zdravnike, ki bo obsegal opis tveganja za zmanjšano delovanje ledvic ob jemanju zdravila Truvada pri odraslih in otrocih ter informacije o uporabi tega zdravila pri odraslih za predekspozicijsko profilakso.
English: Truvada is used in combination with at least one other HIV medicine to treat adults infected with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Slovenian: Zdravilo Truvada se uporablja v kombinaciji z vsaj enim drugim zdravilom proti virusu HIV za zdravljenje odraslih, okuženih z virusom humane imunske pomanjkljivosti tipa 1 (HIV-1), tj. virusom, ki povzroča sindrom pridobljene imunske pomanjkljivosti (aids).
English: Both emtricitabine and tenofovir work in similar ways by blocking the activity of reverse transcriptase, an enzyme produced by HIV that allows it to infect cells and make more viruses.
Slovenian: Emtricitabin in tenofovir na podoben način zavirata delovanje reverzne transkriptaze, tj. encima, ki ga tvori virus HIV, s katerim lahko ta okuži celice ter tvori še več virusov.
English: For pre-exposure prophylaxis of HIV-1 infection, it is expected that Truvada in the blood will stop the virus from multiplying and spreading from the site of infection in case the individual is exposed to the virus.
Slovenian: Pri predekspozicijski profilaksi okužbe z virusom HIV-1 naj bi zdravilo Truvada v krvi preprečilo razmnoževanje in širjenje virusa z mesta okužbe v primeru izpostavljenosti posameznika virusu.
English: Individuals taking Truvada to prevent HIV-1 infection should be tested at least every 3 months to make sure that they are free of HIV-1.
Slovenian: Osebe, ki jemljejo zdravilo Truvada za preprečitev okužbe z virusom HIV-1, morajo vsaj vsake tri mesece s testiranjem preveriti, da niso okužene z njim.
English: The first study compared the combination of emtricitabine and tenofovir disoproxil with the combination of lamivudine and zidovudine (other antiviral medicines).
Slovenian: V prvi študiji so primerjali kombinacijo emtricitabina in dizoproksiltenofovirata s kombinacijo lamivudina in zidovudina (drugih protivirusnih zdravil).
English: Truvada is also used to help prevent sexually transmitted HIV-1 infection in adults and adolescents who are at high risk of being infected (pre-exposure prophylaxis or PrEP).
Slovenian: Uporablja se tudi kot pomoč za preprečevanje spolno prenosljive okužbe z virusom HIV-1 pri odraslih in mladostnikih, pri katerih je tveganje za okužbo veliko (predekspozicijska profilaksa oziroma PrEP).
English: How is Truvada used?
Slovenian: Kako se zdravilo Truvada uporablja?
English: How does Truvada work?
Slovenian: Kako zdravilo Truvada deluje?
English: The most common side effects in adults treated with Truvada are diarrhoea and nausea (feeling sick).
Slovenian: Najpogostejša neželena učinka pri odraslih, ki se zdravijo z zdravilom Truvada, sta driska in navzea (siljenje na bruhanje).
English: In children, skin discoloration and anaemia (low red blood cell counts) are also common side effects.
Slovenian: Pri otrocih sta pogosta neželena učinka tudi sprememba obarvanosti kože in anemija (nizka raven rdečih krvničk).
English: Two main studies have examined the effects of Truvada's active substances, emtricitabine and tenofovir disoproxil, in adults infected with HIV-1 who had not been treated before.
Slovenian: V dveh glavnih študijah so proučevali učinke zdravilnih učinkovin v zdravilu Truvada, emtricitabina in dizoproksiltenofovirata, pri odraslih, okuženih z virusom HIV-1, ki pred tem še niso bili zdravljeni.
English: The second study examined the effects of emtricitabine and tenofovir disoproxil, taken with lopinavir and ritonavir (other antiviral medicines) in 196 patients with HIV-1 infection.
Slovenian: V drugi študiji so proučevali učinke jemanja emtricitabina in dizoproksiltenofovirata skupaj z lopinavirjem in ritonavirjem (drugima protivirusnima zdraviloma) pri 196 bolnikih z okužbo z virusom HIV-1.
English: Of the individuals taking Truvada, 0.8% (13 out of 1,576) tested positive for HIV-1 infection over 1 year compared with 3.3% (52 out of 1,578) of those taking placebo.
Slovenian: Med tistimi, ki so jemali zdravilo Truvada, je bilo v enem letu testiranje za okužbo z virusom HIV-1 pozitivno pri 0,8 % (13 od 1 576), med tistimi, ki so jemali placebo, pa pri 3,3 % (52 od 1 578).
English: In the first study involving over 2,400 men who have sex with men, 3.9% (48 out of 1,224) individuals taking Truvada tested positive for HIV-1 infection compared with 6.8% (83 out of 1,217) individuals taking placebo.
Slovenian: V prvi študiji, v katero je bilo vključenih 2 400 moških, ki spolno občujejo z moškimi, je bilo testiranje za okužbo z virusom HIV-1 pozitivno pri 3,9 % (48 od 1 224) tistih, ki so jemali zdravilo Truvada, in pri 6,8 % (83 od 1 217) tistih, ki so jemali placebo.
English: Of the patients taking the active substances of Truvada, 80% (194 out of 244) achieved and maintained viral load below 50 HIV1 copies/ml by 48 weeks, compared with 70% of the patients taking the comparator medicines (171 out of 243).
Slovenian: Do 48. tedna je bilo pri 80 % (194 od 244) bolnikov, ki so jemali zdravilni učinkovini v zdravilu Truvada, doseženo in vzdrževano virusno breme pod 50 kopij HIV-1/ml v primerjavi s 70 % (171 od 243) bolnikov, ki so jemali primerjalni zdravili.
English: In both studies Truvada was compared with placebo (a dummy treatment) in adults at high risk of sexually transmitted HIV-1 infection.
Slovenian: V obeh študijah so zdravilo Truvada primerjali s placebom (zdravilom brez zdravilne učinkovine) pri odraslih z velikim tveganjem za okužbo s spolno prenosljivim virusom HIV-1.
English: Truvada can only be obtained with a prescription, and treatment should be started by a doctor who has experience in the management of HIV infection.
Slovenian: Predpisovanje in izdaja zdravila Truvada je le na recept, zdravljenje z njim pa mora uvesti zdravnik, ki ima izkušnje z zdravljenjem okužbe z virusom HIV.
English: Truvada contains two active substances: emtricitabine, which is a nucleoside reverse transcriptase inhibitor; and tenofovir disoproxil, which is a ‘prodrug' of tenofovir.
Slovenian: Zdravilo Truvada vsebuje dve zdravilni učinkovini: emtricitabin, ki je nukleozidni zaviralec reverzne transkriptaze, in dizoproksiltenofovirat, ki je „predzdravilo“ zdravila tenofovir.
English: For the full list of all side effects reported with Truvada, see the package leaflet.
Slovenian: Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Truvada, glejte navodilo za uporabo.
English: Truvada can be used for pre-exposure prophylaxis only in individuals who have been tested to be free of HIV infection.
Slovenian: Za predekspozicijsko profilakso se zdravilo Truvada lahko uporablja samo pri osebah, pri katerih je bila s testiranjem potrjena odsotnost okužbe z virusom HIV.
English: Both combinations were taken with efavirenz (another antiviral medicine) by patients with HIV-1 infection.
Slovenian: Obe kombinaciji zdravil so bolniki z okužbo z virusom HIV-1 jemali sočasno z efavirenzom (drugim protivirusnim zdravilom).
English: Do not store above 30°C.
Slovenian: Shranjujte pri temperaturi do 30 C.
English: Date of first authorisation: 4 June 2010 Date of latest renewal: 19 March 2015
Slovenian: Datum prve odobritve: 4. junij 2010 Datum zadnjega podaljšanja: 19. marec 2015
English: It is important that you take Tolura every day until your doctor tells you otherwise.
Slovenian: Pomembno je, da jemljete zdravilo Tolura vsak dan, dokler vam zdravnik ne naroči drugače.
English: You should see your doctor immediately if you experience any of the following symptoms:
Slovenian: Nemudoma morate obiskati zdravnika, če se pojavi kateri od naslednjih simptomov:
English: If you feel dizzy or tired, do not drive or operate machinery.
Slovenian: Če ste omotični ali utrujeni, ne vozite in ne upravljajte strojev.
English: Thus it is important to regularly measure blood pressure to verify if it is within the normal range.
Slovenian: Zato je pomembno, da krvni tlak redno merimo in tako preverjamo, ali je v normalnem območju.
English: If you forget to take a dose, do not worry.
Slovenian: Če ste pozabili vzeti odmerek zdravila, naj vas ne skrbi.
English: See also information under the heading “Do not take Tolura”.
Slovenian: Glejte tudi informacije pod naslovom “Ne jemljite zdravila Tolura”.
English: The tablets should be swallowed with some water or other non-alcoholic drink.
Slovenian: Tablete morate pogoltniti z malo vode ali druge brezalkoholne pijače.
English: Your doctor may need to change the dose of these other medicines or take other precautions.
Slovenian: Zdravnik bo morda moral spremeniti odmerek teh zdravil ali uvesti druge previdnostne ukrepe.
English: In some cases you may have to stop taking one of the medicines.
Slovenian: V nekaterih primerih boste morali katero od teh zdravil prenehati jemati.
English: BLISTER/OPA/Al/PVC Al
Slovenian: PRETISNI OMOT/ OPA/Al/PVC Al
English: Some side effects can be serious and need immediate medical attention:
Slovenian: Nekateri neželeni učinki so lahko resni in zahtevajo takojšnjo zdravstveno oskrbo.
English: The marketing authorisation holder shall submit periodic safety update reports for this product in accordance with the requirements set out in the list of Union reference dates (EURD list)) provided for under Article 107c(7) of Directive 2001/83/EC and published on the European medicines web-portal.
Slovenian: Imetnik dovoljenja za promet z zdravilom mora redno posodobljena poročila o varnosti zdravila za to zdravilo predložiti v skladu z zahtevami, določenimi v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES in objavljenem na evropskem spletnem portalu o zdravilih.
English: You may notice this as dizziness when standing up.
Slovenian: Ta učinek boste opazili kot omotico med vstajanjem.
English: Take it as soon as you remember then carry on as before.
Slovenian: Vzemite ga takoj, ko se spomnite, in z jemanjem nadaljujte kot običajno.
English: 1, 2, 3, 4: for further descriptions, please see sub-section “Description of selected adverse reactions”
Slovenian: 1, 2, 3, 4: Za podrobnejši opis glejte podpoglavje »Opis izbranih neželenih učinkov«
English: You can take Tolura with or without food.
Slovenian: Zdravilo Tolura lahko jemljete s hrano ali brez nje.
English: 02-235 Warszawa Poland
Slovenian: 02-235 Warszawa Poljska
English: Therefore, the combination should be administered with caution, especially in the elderly.
Slovenian: Zato je treba kombinacijo dajati previdno, še zlasti starejšim bolnikom.
English: The incidence of adverse reactions was not dose related and showed no correlation with gender, age or race of the patients.
Slovenian: Pogostost neželenih dogodkov ni bila povezana z odmerkom in ni kazala korelacije s spolom, starostjo ali raso bolnika.