FrancophonIA/ELRC3.0 huggingface dataset:
English: Cmin: ↑ 51% (↑ 37 to ↑ 66) Higher tenofovir concentrations could potentiate tenofovirassociated adverse events, including renal disorders.
Croatian: Cmin: ↑ 51 % (↑ 37 do ↑ 66) Više koncentracije tenofovira mogu potencirati štetne događaje povezane s tenofovirom, uključujući poremećaje u radu bubrega.
English: If you think that you may have any of these serious side effects, talk to your doctor.
Croatian: Mislite li da imate bilo koju od ovih ozbiljnih nuspojava, obratite se svojem liječniku.
English: Interrupting treatment with efavirenz/emtricitabine/tenofovir disoproxil should also be considered in case of progressive decline of renal function when no other cause has been identified.
Croatian: Prekid terapije efavirenzom/emtricitabinom/tenofovirdizoproksilom također treba razmotriti u slučaju progresivnog slabljenja funkcije bubrega ako se nije utvrdio nijedan drugi uzrok.
English: Emtricitabine and tenofovir disoproxil: A large amount of data on pregnant women (more than 1,000 pregnancy outcomes) indicates no malformations or foetal/neonatal toxicity associated with emtricitabine and tenofovir disoproxil.
Croatian: Emtricitabin i tenofovirdizoproksil: brojni podaci u trudnica (više od 1000 trudnoća) ne ukazuju na malformacije ili fetalnu/neonatalnu toksičnost povezanu s emtricitabinom i tenofovirdizoproksilom.
English: Efavirenz is an NNRTI of HIV-1.
Croatian: Efavirenz je NNRTI lijek za HIV-1.
English: Two additional cases (1 prospective and 1 retrospective) including events consistent with neural tube defects have been reported with the fixed-dose combination tablet containing efavirenz, emtricitabine, and tenofovir disoproxil.
Croatian: Prijavljena su dva dodatna slučaja (1 prospektivni i 1 retrospektivni) koja su uključivala događaje s oštećenjem neuralne cijevi s primjenom tableta s fiksnom kombinacijom efavirenza, emtricitabina i tenofovirdizoproksila.
English: 1 Other efavirenz resistance mutations included A98G (n=1), K103E (n=1), V179D (n=1), and M230L (n=1).
Croatian: 1 Druge mutacije za rezistenciju na efavirenz uključivale su A98G (n = 1), K103E (n = 1), V179D (n = 1) i M230L (n = 1).
English: Multipack size: 90 (3 packs of 30) tablets
Croatian: Veličina višestrukog pakiranja: 90 (3 pakiranja po 30) tableta
English: - Medicines used to prevent organ transplant rejection (also called immunosuppressants), such as cyclosporine, sirolimus or tacrolimus.
Croatian: - Lijekovi koji se koriste za sprječavanje odbacivanja transplantiranih organa (poznati i pod nazivom imunosupresivi), kao što su ciklosporin, sirolimus ili takrolimus.
English: - if you are allergic to efavirenz, emtricitabine, tenofovir, tenofovir disoproxil or any of the other ingredients of this medicine (listed in section 6).
Croatian: - ako ste alergični na efavirenz, emtricitabin, tenofovir, tenofovirdizoproksil ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan is a treatment for Human Immunodeficiency Virus (HIV) infection in adults aged 18 years and over who have previously been treated with other antiretroviral medicines and have their HIV-1 infection under control for at least three months.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan namijenjen je za liječenje infekcije virusom humane imunodeficijencije (HIV) odraslih osoba u dobi od 18 godina i više koje su prethodno bile liječene drugim antiretrovirusnim lijekovima i njihova je infekcija virusom HIV-1 pod kontrolom najmanje tri mjeseca.
English: Each tablet also contains 105.5 mg of lactose per tablet.
Croatian: Svaka tableta sadržava i 105,5 mg laktoze po tableti.
English: Administration of efavirenz capsules with a high fat meal increased the mean AUC and Cmax of efavirenz by 28% and 79%, respectively, compared to administration in a fasted state.
Croatian: Primjena kapsula efavirenza uz obrok s velikom količinom masnoće povećala je srednju vrijednost AUC i Cmax efavirenza za 28 %, odnosno 79 %, u usporedbi s davanjem natašte.
English: Interactions between efavirenz/emtricitabine/tenofovir disoproxil or its individual component(s) and other medicinal products are listed in Table 1 below (increase is indicated as ‘↑', decrease as ‘↓', no change as ‘↔', twice daily as ‘b.i.d.
Croatian: Interakcije između efavirenza/emtricitabina/tenofovirdizoproksila ili njegovih pojedinačnih komponenti i drugih lijekova navedene su u nastavku u Tablici 1 (povećanje je označeno kao „↑”, smanjenje kao „↓”, bez promjene kao „↔”, dvaput na dan kao „b.i.d.”, jedanput na dan kao „q.d.” i svakih 8 sati kao „q8h”).
English: Cholesterol levels should be periodically monitored.
Croatian: Potrebna je povremena kontrola razina kolesterola.
English: Genotoxicity studies revealed positive results in the in vitro mouse lymphoma assay, equivocal results in one of the strains used in the Ames test, and weakly positive results in an UDS test in primary rat hepatocytes.
Croatian: Ispitivanja genotoksičnosti dala su pozitivne rezultate u in vitro testu mišjeg limfoma, nepouzdane rezultate u jednom soju upotrijebljenom u Amesovom testu i slabo pozitivne rezultate UDS testa (UDS, engl. unscheduled DNA synthesis; test neplanirane DNK sinteze) na primarnim hepatocitima štakora.
English: • liver and pancreas problems • increased fatty acids (triglycerides), bilirubin or sugar levels in the blood
Croatian: • povišene trigliceride (masne kiseline), bilirubin ili šećer u krvi
English: Pack size: 30 tablets
Croatian: Veličina pakiranja: 30 tableta
English: In vitro studies have determined that neither tenofovir disoproxil nor tenofovir are substrates for the CYP enzymes.
Croatian: In vitro ispitivanja pokazala su da ni tenofovirdizoproksil ni tenofovir nisu supstrati za CYP enzime.
English: The oral bioavailability of tenofovir from tenofovir disoproxil in fasted patients was approximately 25%.
Croatian: Peroralna bioraspoloživost tenofovira iz tenofovirdizoproksila u bolesnika natašte bila je približno 25 %.
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan contains three active substances that are used to treat human immunodeficiency virus (HIV) infection:
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan sadržava tri djelatne tvari koje se koriste za liječenje infekcije virusom humane imunodeficijencije (HIV):
English: Liver enzyme monitoring should be considered for all patients independent of pre-existing hepatic dysfunction or other risk factors.
Croatian: Nužno je uzeti u obzir nadzor jetrenih enzima kod svih bolesnika, bez obzira na prethodna postojeća oštećenja funkcije jetre ili druge faktore rizika.
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan should be taken on an empty stomach (commonly defined as 1 hour before or 2 hours after a meal) preferably at bedtime.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan treba se uzimati na prazan želudac (stanje koje se obično definira kao 1 sat prije ili 2 sata nakon jela), po mogućnosti prije spavanja.
English: If you are taking any of these medicines, your doctor may need to check the level of anticonvulsant medicine in your blood to ensure that it is not affected while taking Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan.
Croatian: Uzimate li bilo koji od tih lijekova, Vaš liječnik mora provjeriti razinu antikonvulziva u Vašoj krvi da bi se osiguralo da se ona nije promijenila zbog uzimanja lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan.
English: - Medicines used to lower blood fats (also called statins): Atorvastatin, pravastatin, simvastatin.
Croatian: - Lijekovi koji se koriste za snižavanje razine masnoća u krvi (poznati i pod nazivom statini): atorvastatin, pravastatin, simvastatin.
English: K103N was the most frequently observed RT substitution in viral isolates from patients who experienced rebound in viral load during clinical studies of efavirenz.
Croatian: K103N je bila najčešće opažena RT supstitucija pri virusnim izolatima dobivenim od bolesnika kod kojih je tijekom kliničkih ispitivanja efavirenza došlo do povećanja koncentracije virusa.
English: Compared to fasted administration, dosing of tenofovir disoproxil and emtricitabine in combination with either a high fat meal or a light meal increased the mean AUC of tenofovir by 43.6% and 40.5%, and Cmax by 16% and 13.5%, respectively without affecting emtricitabine exposures.
Croatian: U usporedbi s davanjem natašte, doziranje tenofovirdizoproksila i emtricitabina u kombinaciji s obrokom s velikom količinom masnoće ili laganim obrokom povećalo je srednju vrijednost AUC-a tenofovira za 43,6 % odnosno 40,5 % i vrijednost Cmax tenofovira za 16 % odnosno 13,5 %, bez utjecaja na izloženost emtricitabinu
English: If you have taken Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Croatian: Ako ste Efavirenz/emtricitabin/tenofovirdizoproksil Mylan uzimali tijekom trudnoće, postoji mogućnost da liječnik zatraži redovito provođenje pretraga krvi i drugih dijagnostičkih pretraga kako bi pratio razvoj Vašega djeteta.
English: - Warfarin or acenocoumarol (medicines used to reduce clotting of the blood): Your doctor may need to adjust your dose of warfarin or acenocoumarol.
Croatian: - Varfarin ili acenokumarol (lijekovi koji se koriste za smanjenje zgrušavanja krvi): liječnik će možda morati prilagoditi dozu varfarina ili acenokumarola.
English: - Medicines used to treat bacterial infections, including tuberculosis and AIDS-related mycobacterium avium complex: Clarithromycin, rifabutin, rifampicin.
Croatian: - Lijekovi koji se koriste za liječenje bakterijskih infekcija, uključujući tuberkulozu i infekciju bakterijama skupine mycobacterium avium complex koja je povezana sa SIDA-om: klaritromicin, rifabutin, rifampicin.
English: Cmax: ↔ 11% (CYP3A induction - effect on boceprevir) *0-8 hours
Croatian: Cmax: ↔ 11 %* (indukcija CYP3A- učinak na boceprevir) *0 - 8 sati
English: Multipack: 90 (3 packs of 30) film-coated tablets.
Croatian: Višestruko pakiranje: 90 (3 pakiranja po 30) filmom obloženih tableta
English: PHARMACEUTICAL FORM AND CONTENTS Film-coated tablet
Croatian: OBLIK I SADRŽAJ Filmom obložena tableta
English: • angry behaviour, suicidal thoughts, strange thoughts, paranoia, unable to think clearly, mood being affected, seeing or hearing things that are not really there (hallucinations), suicide attempts, personality change (psychosis), catatonia (a condition in which the patient is rendered motionless and speechless for a period)
Croatian: • srdito ponašanje, samoubilačke misli, neobične misli, paranoja, nemogućnost jasnog razmišljanja, promjene raspoloženja, osoba čuje ili vidi stvari koje nisu stvarne (halucinacije),
English: Each dose also contains 105.5 mg of lactose.
Croatian: Svaka doza sadržava i 105,5 mg laktoze.
English: - This medicine contains sodium metabisulfite and lactose.
Croatian: - Ovaj lijek sadržava natrijev metabisulfit i laktozu.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON OF BOTTLE MULTIPACK (WITH BLUE BOX)
Croatian: PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU VANJSKA KUTIJA VIŠESTRUKOG PAKIRANJA BOCE (S PLAVIM OKVIROM)
English: Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan may interact with other medicines, including herbal preparations such as Ginkgo biloba extracts.
Croatian: Efavirenz/emtricitabin/tenofovirdizoproksil Mylan može imati interakcije s drugim lijekovima, uključujući biljne pripravke kao što je ekstrakt Ginkgo biloba.
English: Each film-coated tablet contains 7.5 mg of sodium metabisulfite and 105.5 mg of lactose monohydrate.
Croatian: Jedna filmom obložena tableta sadržava 7,5 mg natrijeva metabisulfita i 105,5 mg laktoze hidrata.
English: All 3 subjects had received a fixed dose combination of lamivudine and zidovudine and efavirenz for 144 weeks and then switched to efavirenz/emtricitabine/tenofovir disoproxil.
Croatian: Sva 3 ispitanika primala su fiksnu dozu kombinacije lamivudina i zidovudina i efavirenz 144 tjedna, a potom su bili prebačeni na efavirenz/emtricitabin/tenofovirdizoproksil.
English: IMMUNOSUPPRESSANTS Immunosuppressants metabolised by CYP3A4 (e.g. cyclosporine, tacrolimus, sirolimus)/Efavirenz
Croatian: Imunosupresivi koji se metaboliziraju enzimom CYP3A4 (npr. ciklosporin, takrolimus, sirolimus)/efavirenz
English: These drugs include: - antiarrhythmics of classes IA and III, - neuroleptics, antidepressive agents, - certain antibiotics including some agents of the following classes: macrolides,
Croatian: Ti lijekovi uključuju: - antiaritmike skupina IA i III - neuroleptike, antidepresive - određene antibiotike uključujući neke lijekove iz sljedećih skupina: makrolidi, fluorokinoloni,
English: Common elevated aspartate aminotransferase (AST), elevated alanine aminotransferase (ALT), elevated gammaglutamyltransferase (GGT)
Croatian: Poremećaji jetre i žuči: Često povišena aspartat aminotransferaza (AST), povišena alanin aminotransferaza (ALT), povišena gama- glutamil transferaza (GGT)
English: - Medicines containing didanosine (for HIV infection): Taking Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan with other antiviral medicines that contain didanosine can raise the levels of didanosine in your blood and may reduce CD4 cell counts.
Croatian: - Lijekovi koji sadržavaju didanozin (za liječenje infekcije HIV-om): Uzimanjem lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan s drugim antivirusnim lijekovima koji sadržavaju didanozin može Vam se povećati razina didanozina u krvi i smanjiti broj CD4 stanica.
English: Psychiatric disorders: Common depression (severe in 1.6%)3, anxiety3, abnormal dreams3, insomnia3
Croatian: Psihijatrijski poremećaji: Često depresija (teška u 1,6 % slučajeva)3, anksioznost3, abnormalni snovi3, nesanica3
English: Limited clinical experience in patients co-infected with HIV and HBV suggests that treatment with emtricitabine or tenofovir disoproxil in antiretroviral combination therapy to control HIV infection also results in a reduction in HBV DNA (3 log10 reduction or 4 to 5 log10 reduction, respectively) (see section 4.4).
Croatian: Ograničeno kliničko iskustvo u bolesnika koji su istovremeno inficirani HIV-om i HBV-om navodi na zaključak da liječenje s emtricitabinom ili tenofovirdizoproksilom u kombiniranoj antiretrovirusnoj terapiji, u cilju kontroliranja infekcije HIV-om također rezultira smanjenjem HBV DNK (smanjenje od 3 log10 odnosno smanjenje od 4 do 5 log10 (vidjeti dio 4.4).
English: If there is evidence of worsening liver disease or persistent elevations of serum transaminases to greater than 5 times the upper limit of the normal range, the benefit of continued therapy with efavirenz/emtricitabine/tenofovir disoproxil needs to be weighed against the potential risks of significant liver toxicity.
Croatian: Postoje li dokazi o pogoršanju bolesti jetre ili stalno povišenje serumskih transaminaza za više od 5 puta iznad gornje granice normalnog raspona, nužno je odmjeriti koristi nastavka terapije efavirenzom/emtricitabinom/tenofovirdizoproksilom naprema mogućim rizicima značajne toksičnosti za jetru.
English: Tenofovir disoproxil is converted in vivo to tenofovir, a nucleoside monophosphate (nucleotide) analogue of adenosine monophosphate.
Croatian: Tenofovirdizoproksil se pretvara in vivo u tenofovir, nukleozidni monofosfatni (nukleotidni) analog adenozin monofosfata.
English: Pink capsule-shaped, biconvex, beveled-edge film-coated tablet, approximately 21 mm x 11 mm and debossed with ‘M' on one side and ‘TME' on the other side.
Croatian: Ružičasta bikonveksna, filmom obložena tableta u obliku kapsule s ukošenim rubom približne veličine 21 mm × 11 mm s utisnutom oznakom „M” na jednoj strani i „TME” na drugoj strani.
English: If you could get pregnant while receiving Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan, you need to use a reliable form of barrier contraception (for example, a condom) with other methods of contraception including oral (pill) or other hormonal contraceptives (for example, implants, injection).
Croatian: Ako postoji mogućnost da zatrudnite tijekom uzimanja lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, trebate koristiti pouzdan oblik barijerne kontracepcije (primjerice, kondom) u kombinaciji s drugim metodama kontracepcije, uključujući oralne (pilula) i druge hormonalne kontraceptive (na primjer, implantati, injekcije).
English: 3 See section 4.8 Description of selected adverse reactions for more details.
Croatian: 3 Dodatne podatke potražite u dijelu 4.8 Opis odabranih nuspojava.
English: Table 5: Maintenance of pure virologic response (Kaplan Meier% (Standard Error) [95%CI]) at week 48 for treatment-experienced patients with baseline HIV-1 RNA < 75 copies/ml who had therapy switched to efavirenz/emtricitabine/tenofovir disoproxil according to the type of prior antiretroviral regimen (Kaiser Permanente patient database)
Croatian: Tablica 5: Održavanje čistog virološkog odgovora (% po Kaplan-Meierovoj metodi (standardna pogreška) [95 %CI]) u 48. tjednu za prethodno liječene bolesnike s početnom raznom HIV-1 RNA < 75 kopija/ml koji su prešli na liječenje efavirenzom/emtricitabinom/tenofovirdizoproksilom u skladu s vrstom prethodnog antiretrovirusnog režima (baza podataka bolesnika Kaiser Permanente)
English: Although in vitro data suggest that efavirenz inhibits CYP2C9 and CYP2C19, there have been contradictory reports of both increased and decreased exposures to substrates of these enzymes when coadministered with efavirenz in vivo.
Croatian: Iako podaci in vitro pokazuju da efavirenz inhibira CYP2C9 i CYP2C19, postoje kontradiktorna izvješća kako o povećanoj, tako i o smanjenoj izloženosti supstratima ovih enzima kad se primjenjuju istovremeno s efavirenzom in vivo.
English: These patients should be carefully monitored for rises in viral load and, since the safety profile of efavirenz differs from that of protease inhibitors, for adverse reactions.
Croatian: Te bolesnike nužno je pomno pratiti radi mogućnosti povećanja virusnog opterećenja te, budući da se sigurnosni profil efavirenza razlikuje od profila inhibitora proteaze, nuspojava.
English: When you start or stop taking Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan your doctor will closely monitor your plasma levels of the immunosuppressant and may need to adjust its dose.
Croatian: Kada započnete ili prestanete s uzimanjem lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, liječnik će pomno nadzirati razine imunosupresiva u plazmi i možda će morati prilagoditi njihove doze.
English: After 96 weeks of efavirenz/emtricitabine/tenofovir disoproxil treatment, HIV-1 RNA plasma concentrations remained < 50 copies/ml in 82% of patients and < 400 copies/ml in 85% of patients (intention to treat analysis (ITT), missing=failure).
Croatian: Nakon 96 tjedana liječenja efavirenzom/emtricitabinom/tenofovirdizoproksilom, u 82 % bolesnika koncentracija HIV-1 RNA u plazmi zadržana je na < 50 kopija/ml, a u 85 % bolesnika na < 400 kopija/ml (analiza sa svrhom liječenja (ITT), nedostaje = neuspjeh).
English: The net effect of co-administration is not clear.
Croatian: Neto učinak istovremene primjene nije jasan.
English: Based on the concentration-QTc relationship, the mean QTc prolongation and its upper bound 90% confidence interval are 8.7 ms and 11.3 ms in subjects with CYP2B6*6/*6 genotype following the administration of 600 mg daily dose for 14 days (see section 4.5).
Croatian: Na temelju odnosa između koncentracije i QTc-a, srednja vrijednost produljenja QTc-a i gornja granica 90%-tnog intervala pouzdanosti iznose 8,7 ms i 11,3 ms u ispitanika s genotipom CYP2B6*6/*6 nakon primjene dnevne doze od 600 mg tijekom 14 dana (vidjeti dio 4.5).
English: Tenofovir disoproxil and emtricitabine, two of the active substances in Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan, show some activity against hepatitis B virus although emtricitabine is not approved for the treatment of hepatitis B infection.
Croatian: Tenofovirdizoproksil i emtricitabin, dvije od djelatnih tvari koje sadržava lijek Efavirenz/emtricitabin/tenofovirdizoproksil Mylan, pokazuju određenu aktivnost protiv virusa hepatitisa B, iako emtricitabin nije odobren za liječenje infekcije hepatitisa B.
English: Emtricitabine-resistant viruses with the M184V/I mutation were cross-resistant to lamivudine, but retained sensitivity to didanosine, stavudine, tenofovir disoproxil and zidovudine.
Croatian: Virusi rezistentni na emtricitabin s mutacijom M184V/I bili su križno rezistentni na lamivudin, ali su zadržali osjetljivost na didanozin, stavudin, tenofovirdizoproksil i zidovudin.
English: Effects on drug levels
Croatian: Učinci na razinu lijekova
English: This medicinal product contains 7.5 mg of sodium metabisulfite per dose, which may rarely cause severe hypersensitivity reactions and bronchospasm.
Croatian: Ovaj lijek sadržava 7,5 mg natrijeva metabisulfita po dozi, što u rijetkim slučajevima može uzrokovati teške reakcije preosjetljivosti i bronhospazam.
English: Compounds that are substrates of these enzymes may have decreased plasma concentrations when co-administered with efavirenz.
Croatian: Spojevi koji su supstrati ovih enzima mogu imati smanjene koncentracije u plazmi kada se primjenjuju istovremeno s efavirenzom.
English: Renal function should be closely monitored (see section 4.4).
Croatian: Nužno je pomno nadzirati funkciju bubrega (vidjeti dio 4.4).
English: Some patients have had blood tests or symptoms indicating that their hepatitis has got worse after stopping emtricitabine or tenofovir disoproxil (two of the three components of Efavirenz/Emtricitabine/Tenofovir disoproxil Mylan).
Croatian: U nekih su bolesnika krvne pretrage ili simptomi ukazivali da se stanje hepatitisa pogoršalo nakon prestanka uzimanja emtricitabina ili tenofovirdizoproksila (dva od tri sastojka lijeka Efavirenz/emtricitabin/tenofovirdizoproksil Mylan).
English: Data are available from 286 patients who switched to efavirenz/emtricitabine/tenofovir disoproxil: 160 had previously received efavirenz, emtricitabine and tenofovir disoproxil, and 126 had previously received lamivudine/zidovudine and efavirenz.
Croatian: Dostupni su podaci za 286 bolesnika koji su prebačeni na liječenje efavirenzom/emtricitabinom/tenofovirdizoproksilom: 160 njih prethodno je primalo efavirenz, emtricitabin i tenofovirdizoproksil, a 126 je prethodno primalo lamivudin/zidovudin i efavirenz.
English: - Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) - Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) - Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor (NtRTI)
Croatian: - efavirenz je nenukleozidni inhibitor reverzne tranksriptaze (NNRTI) - emtricitabin je nukleozidni inhibitor reverzne transkriptaze (NRTI) - tenofovirdizoproksil je nukleotidni inhibitor reverzne transkriptaze (NtRTI)
English: Table 1: Interactions between efavirenz/emtricitabine/tenofovir disoproxil or its individual components and other medicinal products
Croatian: Tablica 1: Interakcije između efavirenza/emtricitabina/tenofovirdizoproksila ili njegovih pojedinačnih komponenti i drugih lijekova
English: It is indicated for the treatment of human immunodeficiency virus-1 (HIV-1) infection in adults aged 18 years and over with virologic suppression to HIV-1 RNA levels of < 50 copies/ml on their current combination antiretroviral therapy for more than three months.
Croatian: Indicirana je za liječenje odraslih osoba u dobi od 18 godina i više koje su inficirane humanim virusom imunodeficijencije-1 (HIV-1), s virološkom supresijom razina HIV-1 RNK na < 50 kopija/ml na trenutnoj kombiniranoj antiretrovirusnoj terapiji tijekom više od tri mjeseca.