FrancophonIA/ELRC3.0 huggingface dataset:
English: silver foil, and electrically conductive adhesive tape - skin adhesive: polybutene, polyisobutylene, and rosin ester - protective liner: polyester film coated on one side with silicone.
Croatian: - ljepilo za kožu: polibuten, poliizobutilen i ester kolofonija - zaštitna podloga: poliesterski film s jedne strane obložen silikonom.
English: No overall differences were observed in the safety of IONSYS fentanyl 40 micrograms in elderly patients (≥ 65 years including a subpopulation ≥ 75 years) and adult patients for all controlled studies.
Croatian: 40 mikrograma u starijih bolesnika (≥65 godina uključujući subpopulaciju ≥75 godina) i odraslih bolesnika u svim kontroliranim ispitivanjima.
English: Each IONSYS system is packaged in a sealed thermoform tray.
Croatian: Jedan sustav IONSYS pakiran je u zatvorenom, toplinski oblikovanom podlošku.
English: • Press IONSYS firmly in place for at least 15 seconds with the sticky side down on the skin of the chest or upper arm of the patient.
Croatian: • Čvrsto pritisnite IONSYS na mjestu najmanje 15 sekundi s ljepljivom stranom okrenutom prema koži prsišta ili nadlaktice bolesnika.
English: • If at any point during use IONSYS loosens from the skin, a non-allergenic tape may be used to secure the edges to ensure complete contact with the skin.
Croatian: • Ako se u bilo kojem trenutku tijekom primjene IONSYS olabavi od kože, može se koristiti traka za pričvršćivanje rubova koja nije alergena kako bi se osiguralo potpuno prianjanje uz kožu.
English: • You will know the 10-minute dose is complete when the fast blinking green light returns to a slow blinking green light.
Croatian: • Znat ćete da je 10-minutna doza dovršena kada se zeleno svjetlo koje brzo treperi ponovno pretvori u zeleno svjetlo koje sporo treperi.
English: At the end of the self-test, the display will show the number “0” and a green light will flash at a slow rate to indicate IONSYS is ready for application.
Croatian: Na kraju samotestiranja zaslon će prikazivati broj „0“, a zeleno svjetlo će sporo treperiti kako bi označilo da je IONSYS spreman za primjenu.
English: NAME OF THE MEDICINAL PRODUCT AND ROUTE(S) OF ADMINISTRATION IONSYS
Croatian: NAZIV LIJEKA I PUT(EVI) PRIMJENE LIJEKA IONSYS
English: • you are taking medicines for HIV infection (such as ritonavir, nelfinavir, amprenavir or
Croatian: • uzimate lijekove za infekcije HIV-om (kao što su ritonavir, nelfinavir, amprenavir ili fosamprenavir);
English: Hypertension Orthostatic hypotension, Vasodilitation
Croatian: Krvožilni poremećaji hipotenzija hipertenzija ortostatska hipotenzija, vazodilatacija
English: • fluid retention/swelling in the body
Croatian: • zadržavanje tekućine/oticanje tijela
English: Open the sachet containing the drug unit starting at the pre-cut notch and then carefully tearing along the top of the sachet.
Croatian: Otvorite vrećicu koja sadrži odjeljak s lijekom počevši od unaprijed zarezanog dijela vrećice i zatim pažljivo poderite uzduž vrha vrećice.
English: Across the active-controlled studies, dosing with IONSYS was similar to intravenous PCA morphine pump use.
Croatian: U ispitivanjima kontroliranim aktivnim lijekom doziranje sa sustavom IONSYS bilo je slično intravenskom PCA morfinu primijenjenim pumpom.
English: • sneezing, itchiness and blocked or runny nose
Croatian: • kihanje, svrbež i začepljenje ili curenje nosa
English: Hold the Controller in one hand and pull the red tab with the other hand to separate the
Croatian: • Držite kontroler u jednoj ruci i povucite crveni jezičak
English: • you are taking medicines for fungal infections (such as ketoconazole, itraconazole or
Croatian: • uzimate lijekove za gljivične infekcije (kao što su ketokonazol, itrakonazol ili flukonazol);
English: If patients with renal impairment receive IONSYS, they should be observed carefully for signs of fentanyl toxicity.
Croatian: Ako bolesnici s oštećenjem bubrega prime IONSYS, trebaju se pažljivo nadzirati zbog moguće pojave znakova toksičnosti fentanila.
English: The recommended dose Each dose of IONSYS delivers 40 micrograms of fentanyl.
Croatian: Preporučena doza Jedna doza sustava IONSYS isporučuje 40 mikrograma fentanila.
English: IONSYS should be pressed firmly in place for at least 15 seconds with the sticky side down on the skin of the chest or upper arm of the patient.
Croatian: IONSYS se mora čvrsto pritisnuti na mjestu najmanje 15 sekundi s ljepljivom stranom okrenutom prema koži prsišta ili nadlaktice bolesnika.
English: 1 system contains fentanyl hydrochloride equivalent to 9.7 mg of fentanyl.
Croatian: 1 sustav sadrži 9,7 mg fentanila u obliku fentanilklorida.
English: The primary efficacy endpoint was the patient global assessment of method of pain control at 24 hours used to test equivalence between IONSYS and intravenous PCA morphine using a pre-specified ± 10% equivalence boundary with a 2-sided 95% confidence interval.
Croatian: 24 sata korištena za ispitivanje ekvivalencije između sustava IONSYS i intravenskog PCA morfina korištenjem unaprijed definirane ±10%-tne granice ekvivalencije s dvostranim 95%-tnim intervalom pouzdanosti.
English: • Remove the drug unit from the sachet and place on a hard, flat
Croatian: • Izvadite odjeljak s lijekom iz vrećice i stavite ga na tvrdu, ravnu površinu.
English: How IONSYS works
Croatian: Kako IONSYS djeluje
English: Hair at the application site should be clipped (not shaved) before system application.
Croatian: Potrebno je podrezati (ne brijati) dlake na mjestu primjene prije primjene sustava.
English: Published literature has indicated that the CYP3A4*22 and CYP3A5*3 single nucleotide polymorphisms influence fentanyl to norfentanyl metabolism with the potential for increased fentanyl exposure in patients with these genetic polymorphs.
Croatian: Pacijenti s genetskim polimorfizmima koji se odnose na CYP3A4 i CYP3A5 Objavljena literatura ukazuje na to da CYP3A4*22 i CYP3A5*3 jednonukleotidni polimorfizmi utječu na metabolizam fentanila u norfentanil, s potencijalom za povećanu izloženost fentanilu u bolesnika s tim genetskim polimorfima.
English: If the patient requires additional or continuation of pain relief, a new IONSYS may be applied to a new skin site on the upper outer arm or chest.
Croatian: Ako bolesnik zahtijeva dodatno ili daljnje ublažavanje boli, smije se primijeniti novi IONSYS na drugo mjesto na koži na vanjskom dijelu nadlaktice ili na prsištu.
English: Dispose of the folded hydrogel housing in accordance with local requirements for opioid
Croatian: 3. Zbrinite savijeno kućište hidrogela u skladu s lokalnim propisima za opioidne lijekove.
English: Prior to launch of IONSYS in each Member State the Marketing Authorisation Holder (MAH) must agree about the content and format of the educational programme, including communication media, distribution modalities, and any other aspects of the programme, with the National Competent Authority.
Croatian: • Dodatne mjere minimizacije rizika Prije stavljanja lijeka IONSYS u promet u svakoj državi članici, nositelj odobrenja za stavljanje lijeka u promet mora dogovoriti sadržaj i format obrazovnog programa, uključujući medij komunikacije,
English: Each dose of IONSYS delivers 40 micrograms of fentanyl over a 10 minute period, to a maximum of 240 micrograms per hour (6 doses each of 10 minutes duration).
Croatian: Jedna doza sustava IONSYS isporučuje 40 mikrograma fentanila tijekom razdoblja od 10 minuta, do najviše 240 mikrograma na sat (6 doza, svaka u trajanju od 10 minuta).
English: Fentanyl has a well-known abuse potential.
Croatian: Postoji poznata mogućnost zlouporabe fentanila.
English: • If you have any further questions, please ask your doctor or your nurse.
Croatian: • Ako imate dodatnih pitanja, obratite se svom liječniku ili medicinskoj sestri.
English: Dispose of remainder of the system, containing electronics, according to hospital procedures
Croatian: Zbrinite preostali dio sustava, koji sadrži elektroniku, u skladu s postupcima bolnice vezanim za iskorištene baterije.
English: IONSYS delivers a nominal dose of 40 micrograms fentanyl over each 10-minute dosing period at steady state.
Croatian: IONSYS isporučuje nominalnu dozu od 40 mikrograma fentanila tijekom svakog 10-minutnog razdoblja doziranja u stanju dinamičke ravnoteže.
English: The sachet containing the Drug Unit should be opened starting at the pre-cut notch, then by carefully tearing along the top of the sachet.
Croatian: Vrećica koja sadrži odjeljak s lijekom mora se otvoriti počevši od unaprijed zarezanog dijela vrećice, zatim pažljivim trganjem uzduž vrha vrećice.
English: If the medicinal product contacts the skin during removal, the contact area should be thoroughly rinsed with water without using any soap.
Croatian: Ako lijek dođe u dodir s kožom tijekom uklanjanja, potrebno je temeljito isprati mjesto dodira vodom bez uporabe sapuna.
English: Removal and Disposal of IONSYS.
Croatian: Uklanjanje i zbrinjavanje sustava IONSYS
English: Tell your doctor or nurse if you have taken them within the last 14 days before using IONSYS;
Croatian: Obavijestite svog liječnika ili medicinsku sestru ako ste ih uzeli unutar zadnjih 14 dana prije primjene sustava IONSYS; • uzimate lijekove za topikalnu primjenu (tj. lijekove koji se primjenjuju na kožu).
English: At the end of the self-test, the display will show the number 0 and a green light will flash at a slow rate to indicate IONSYS is ready for application.
Croatian: Na kraju samotestiranja zaslon će prikazivati broj 0, a zeleno svjetlo će sporo treperiti kako bi označilo da je IONSYS spreman za primjenu.
English: Fold the hydrogel housing in half with the sticky side facing in. 3.
Croatian: Savijte kućište hidrogela na pola s ljepljivom stranom okrenutom prema unutra.
English: • you have had a chest or upper abdominal operation
Croatian: • ako ste imali operaciju prsišta ili gornjeg dijela trbuha
English: Before any surgery, the healthcare professional should ensure that the patient has been properly informed on how to use IONSYS post-operatively.
Croatian: 4.4 Posebna upozorenja i mjere opreza pri uporabi Prije bilo kojeg kirurškog zahvata, zdravstveni radnik mora osigurati da bolesnik bude ispravno obaviješten kako koristiti IONSYS postoperativno.
English: The safety of IONSYS has not been established in patients with American Society of Anesthesiologists (ASA) physical status classification IV (i.e. patients with a severe systemic disease that is a constant threat to life).
Croatian: American Society of Anesthesiologists, ASA) (tj. bolesnici s teškom sistemskom bolesti koja je stalno opasna po život) nije ustanovljena.
English: The other ingredients are: bottom housing unit: glycol-modified polyethylene terephthalate anode hydrogel: polacrilin, purified water, sodium hydroxide, polyvinyl alcohol cathode hydrogel: purified water, sodium chloride, sodium citrate, polyvinyl alcohol, anhydrous citric acid, cetylpyridinium chloride anode electrode: layers of silver foil and electrically conductive adhesive tape cathode electrode: layers of polyisobutylene/silver chloride/carbon black composite material, silver foil, and electrically conductive adhesive tape skin adhesive: polybutene, polyisobutylene, and rosin ester protective liner: polyester film coated on one side with silicone.
Croatian: Drugi sastojci su: odjeljak donjeg kućišta: glikolom modificiran polietilentereftalat anodni hidrogel: polakrilin, pročišćena voda, natrijev hidroksid, polivinilni alkohol katodni hidrogel: pročišćena voda, natrijev klorid, natrijev citrat, polivinilni alkohol, bezvodna citratna kiselina, cetilpiridinijev klorid anodna elektroda: slojevi srebrne folije i električki provodne ljepljive trake katodna elektroda: slojevi poliizobutilena/srebrovog klorida/ kompozitnog materijala čađe/ srebrne folije i električki provodne ljepljive trake ljepilo za kožu: polibuten, poliizobutilen i ester kolofonija zaštitna podloga: poliesterski film s jedne strane obložen silikonom.
English: The healthcare professional must ensure the patient understands that if they suspect a device failure or malfunction, they must inform a healthcare professional immediately.
Croatian: Zdravstveni radnik mora osigurati da bolesnik razumije da mora odmah obavijestiti zdravstvenog radnika ako posumnja na kvar ili neispravnost uređaja.
English: What IONSYS is used for
Croatian: Za što se IONSYS koristi
English: Complete these steps before applying IONSYS to the patient:
Croatian: Prije primjene sustava IONSYS na bolesnika dovršite ove korake:
English: Migraine Paraesthesia Somnolence Syncope
Croatian: Poremećaji živčanog sustava omaglica glavobolja migrena parestezije somnolencija sinkopa disgeuzija hipoestezija
English: To initiate administration of a fentanyl dose, the patient should press and release the dosing button twice within 3 seconds.
Croatian: Za započinjanje primjene doze fentanila bolesnik mora pritisnuti i otpustiti dugme za doziranje dvaput u roku od 3 sekunde.
English: Refer to the Summary of Product of Characteristics (SmPC) for more information about IONSYS.
Croatian: Vidjeti Sažetak opisa svojstava lijeka za više informacija o sustavu IONSYS.
English: • chest pain, feeling of general discomfort or uneasiness
Croatian: • bol u prsištu, opći osjećaj nelagode ili uznemirenosti
English: The tray is opened by pulling back on the tray lid.
Croatian: Podložak se otvara povlačenjem poklopca podloška unatrag.
English: • Fold the hydrogel housing in half with the sticky side facing
Croatian: • Savijte kućište hidrogela na pola s ljepljivom stranom okrenutom prema unutra.
English: IONSYS will operate for 24 hours after the system is assembled or for 80 doses, whichever comes first, and then becomes inoperative.
Croatian: IONSYS će raditi 24 sata nakon sastavljanja sustava ili dok ne ispostavi 80 doza, što god nastupi prije, a zatim prestaje raditi.
English: If the fentanyl hydrogel contacts the skin during removal, the contact area should be thoroughly rinsed with water without using any soap.
Croatian: Ako fentanil hidrogel dođe u dodir s kožom tijekom uklanjanja, potrebno je temeljito isprati mjesto dodira vodom bez korištenja sapuna.
English: Patients should be titrated to an acceptable level of analgesia prior to initiating use of IONSYS (see section 5.1).
Croatian: Bolesnike treba titrirati do prihvatljive razine analgezije prije početka primjene sustava IONSYS
English: The clear plastic film covering the adhesive should be removed and discarded with care taken not to touch the hydrogels.
Croatian: Potrebno je ukloniti i baciti prozirni plastični pokrov koji prekriva ljepilo pazeći da se ne dodiruju hidrogelovi.
English: (86/1436 or 6%) showed no meaningful difference relative to patients with BMI ≤ 40.
Croatian: U populaciji iz kontroliranih kliničkih ispitivanja, profil nuspojava u bolesnika sa ITM >40 (86/1436 ili 6%) nije pokazao značajne razlike u odnosu na bolesnike sa ITM ≤40.
English: Local arrangements should be in place to ensure that used systems are returned appropriately (e.g., to hospital pharmacies) for disposal of the residual fentanyl in the hydrogel.
Croatian: Potrebno je organizirati se lokalno kako bi se osigurao prikladan povrat iskorištenih sustava (npr.
English: IONSYS is indicated for the management of acute moderate to severe post-operative pain in adult patients.
Croatian: 4.1 Terapijske indikacije IONSYS je indiciran za liječenje akutne umjerene do teške postoperativne boli u odraslih bolesnika.
English: • Steady display number
Croatian: • Stalno prikazan broj
English: • To start a dose from IONSYS, press and release the dosing button twice within 3 seconds.
Croatian: • Za početak primjene doze sustavom IONSYS pritisnite i otpustite dugme za doziranje dvaput u roku od 3 sekunde.
English: What IONSYS is and what it is used for
Croatian: Što je IONSYS i za što se koristi Što je IONSYS
English: • To start a dose, press and release the dosing button 2 times within 3 seconds.
Croatian: • Za početak primjene doze pritisnite i otpustite dugme za doziranje 2 puta u roku od 3 sekunde.
English: See also instructions in SmPC Section 6.6.
Croatian: Vidjeti također upute u dijelu 6.6.
English: CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to special and restricted medical prescription (see Annex I: Summary of Product Characteristics, section 4.2).
Croatian: Lijek se izdaje na poseban i ograničeni recept (vidjeti Dodatak I: Sažetak opisa svojstava lijeka, dio
English: Abnormal dreams Agitation Anxiety
Croatian: Psihijatrijski poremećaji nesanica neuobičajeni snovi agitacija anksioznost konfuzija halucinacije nervoza depresija neuobičajene misli
English: Soap, alcohol, or other solvents should not be used to remove the hydrogel because they may enhance the active substances' ability to penetrate the skin.
Croatian: Za uklanjanje hidrogela ne smiju se koristiti sapun, alkohol ili druga otapala jer bi mogli pojačati sposobnost prodiranja djelatne tvari kroz kožu.
English: IONSYS was also evaluated in four active-control trials (predominantly female (65%), Caucasian (85%), with a mean age of 55 years (range, 18-91 years), and primarily comprised of surgeries including lower abdominal and orthopedic bone procedures) using a standard intravenous patient controlled analgesia (PCA) morphine regimen as the comparator.
Croatian: (65%), bijelci (85%), srednje vrijednosti dobi 55 godina (raspon 18-91 godina) koja su se primarno sastojala od kirurških zahvata koji su uključivali postupke na donjem abdomenu i ortopedske postupke na kostima) uz primjenu morfina kao standardne intravenske analgezije koju nadzire bolesnik (engl. patient controlled analgesia, PCA) kao lijek usporedbe.
English: Patients with hepatic impairment should be observed carefully for signs of fentanyl toxicity.
Croatian: Bolesnike s oštećenom funkcijom jetre treba pažljivo nadzirati zbog moguće pojave znakova toksičnosti fentanila.
English: IONSYS should be administered with caution to patients with moderate or severe hepatic or renal impairment (see section 4.4).
Croatian: Oštećenje funkcije jetre ili bubrega IONSYS je potrebno primjenjivati uz oprez u bolesnika s umjerenim ili teškim oštećenjem funkcije jetre ili bubrega (vidjeti dio 4.4).
English: Do not use IONSYS if you are breast-feeding.
Croatian: Nemojte primjenjivati IONSYS ako dojite.
English: • you have abnormally slow bowel movements or severe constipation
Croatian: • ako imate neuobičajeno sporo pražnjenje crijeva ili teški zatvor
English: Another published article of 52 elderly Japanese post-operative patients receiving continuous intravenous (IV) fentanyl infusion (0.5-1.5 µg/kg/h) showed increased fentanyl exposure in the CYP3A5*3 group (3*/3*) than in the 1* carrier group.
Croatian: Drugi objavljeni članak vezan uz 52 japanska postoperativna bolesnika koji su primali kontinuiranu intravensku (i.v.) infuziju fentanila (0,5-1,5 µg/kg/h) je pokazao povećanu izloženost fentanilu u
English: Topical medicines
Croatian: Topikalni lijekovi
English: Each IONSYS is designed to deliver up to 80 10-minute doses of fentanyl over a period of 24 hours.
Croatian: Jedan IONSYS dizajniran je za isporuku do 80 10-minutnih doza fentanila tijekom razdoblja od 24
English: Preparation of the Application Site
Croatian: Priprema mjesta primjene
English: MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS TRAY LABEL
Croatian: PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE NALJEPNICA NA PODLOŠKU
English: The concomitant use of potent CYP3A4 inhibitors (e.g., as ritonavir, ketoconazole, itraconazole, troleandomycin, clarithromycin, and nelfinavir) or moderate CYP3A4 inhibitors (e.g., amprenavir, aprepitant, diltiazem, erythromycin, fluconazole, fosamprenavir, grapefruit juice, and verapamil) with IONSYS may result in an increase in fentanyl plasma concentrations, which could increase or prolong both the therapeutic effect and adverse reactions, and may cause serious respiratory depression.
Croatian: Istodobna primjena snažnih inhibitora CYP3A4 (npr. ritonavira, ketokonazola, itrakonazola, troleandomicina, klaritromicina i nelfinavira) ili umjerenih inhibitora CYP3A4 (npr. amprenavira, aprepitanta, diltiazema, eritromicina, flukonazola, fosamprenavira, soka od grejpa i verapamila) sa sustavom
English: IONSYS (fentanyl 40 micrograms per dose transdermal system, maximum of 80 doses (3.2 mg/24 hours)).
Croatian: IONSYS (fentanil 40 mikrograma po dozi transdermalni sustav, do najviše 80 doza (3,2 mg/24 sata)).
English: 1 system delivers 40 micrograms fentanyl per dose, to a maximum of 80 doses (3.2 mg/24 hours).
Croatian: 1 sustav isporučuje 40 mikrograma fentanila po dozi, do najviše 80 doza (3,2 mg/24 sata).
English: Elderly patients (≥ 65 years) made up 28% (499/1763) of the total controlled clinical trial exposure to
Croatian: Stariji bolesnici (≥65 godina) sačinjavali su 28% (499/1763) ukupne izloženosti sustavu IONSYS 40 mikrograma u kontroliranim kliničkim ispitivanjima, a približno 10% (174/1763) izloženosti bila je u bolesnika ≥75 godina.
English: These studies evaluated IONSYS vs. intravenous PCA morphine in various surgical procedures commonly seen in clinical practice.
Croatian: morfina u raznim kirurškim zahvatima koji se uobičajeni u kliničkoj praksi.
English: • IONSYS Instructions for Use and Disposal
Croatian: • Upute za primjenu i zbrinjavanje lijeka IONSYS
English: • Gloves must be worn while removing IONSYS from the skin and care should be taken to avoid touching the hydrogels.
Croatian: • Prilikom uklanjanja sustava IONSYS s kože moraju se nositi rukavice i potreban je oprez da se ne dodiruju hidrogelovi.
English: Open the tray by peeling back the tray lid.
Croatian: Otvorite podložak tako da povučete unatrag poklopac podloška.
English: See package leaflet for disposal information.
Croatian: Vidjeti uputu o lijeku za informacije o zbrinjavanju.
English: Skin and subcutaneous tissue disorders
Croatian: Poremećaji kože i potkožnog tkiva svrbež osip hiperhidroza
English: The green light will switch off and the number of doses delivered will flash on and off. No more doses can be delivered after this and IONSYS will be removed by your doctor or nurse.
Croatian: Nakon toga se ne može isporučiti nijedna doza, a IONSYS će ukloniti liječnik ili medicinska sestra.
English: Place a new system on a different skin site
Croatian: Stavite novi sustav na drugo mjesto na koži
English: Tolerance, physical dependence, and psychological dependence may develop upon repeated administration of opioids.
Croatian: Kod ponovljene primjene opioida može se pojaviti tolerancija, fizička ovisnost i psihička ovisnost.
English: • swelling, itching, irritation or blistering of skin at the patch site
Croatian: • oticanje, svrbež, nadraženost ili mjehurići na koži na mjestu primjene flastera
English: Table 1: Placebo-controlled Trials (N=727) Patients Percent (n) of patients who withdrew due to inadequate analgesia Hours 3-24
Croatian: Postotak (n) bolesnika koji su prekinuli liječenje zbog neadekvatne analgezije Sati 3-24
English: QUALITATIVE AND QUANTITATIVE COMPOSITION Each IONSYS system contains fentanyl hydrochloride equivalent to 9.7 mg of fentanyl and delivers 40 micrograms fentanyl per dose, to a maximum of 80 doses (3.2 mg/24 hours).
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedan sustav IONSYS sadrži 9,7 mg fentanila u obliku fentanilklorida i isporučuje 40 mikrograma fentanila po dozi, do najviše 80 doza (3,2 mg/24 sata).
English: IONSYS should also be removed prior to a magnetic resonance imaging (MRI) procedure, X-ray or CT scan.
Croatian: IONSYS se također treba ukloniti prije postupka snimanja magnetskom rezonancijom
English: Once comfortable, patients were then randomized to either IONSYS or intravenous PCA morphine treatment.
Croatian: Nakon što je postignuta adekvatna analgezija, bolesnici su radnomizirani u skupinu koja je primala terapiju sustavom IONSYS ili intravenskim PCA morfinom.
English: Infections and infestations
Croatian: Infekcije i infestacije rinitis
English: Patients should not get IONSYS wet.
Croatian: Bolesnicima se ne smije primijeniti IONSYS dok su mokri.
English: The active substance in IONSYS is fentanyl hydrochloride.
Croatian: Što IONSYS sadržiDjelatna tvar u sustavu IONSYS je fentanilklorid.
English: Action required
Croatian: Potrebna radnja