FrancophonIA/ELRC3.0 huggingface dataset:
English: - Convulsion (seizure) - Headache - Vomiting - Changes in blood tests of liver function - Rash, pruritis (itching) - Changes in blood tests of kidney function - Abnormal flow of bile from the gallbladder into the intestine (cholestasis) - High blood sugar - High blood pressure - Low blood pressure - Sudden contraction of the muscles around the airways resulting in wheezing or coughing - Difficulty of breathing
Croatian: - konvulzije (napadaji) - glavobolja - povraćanje - promjene u nalazima krvnih pretraga funkcije jetre - osip, svrbež (pruritus) - promjene u nalazima krvnih pretraga funkcije bubrega - smetnje otjecanja žuči iz žučnog mjehura u crijevo (kolestaza) - povišeni šećer u krvi - povišeni krvni tlak - sniženi krvni tlak - iznenadno stezanje mišića oko dišnih puteva koje uzrokuje piskanje ili kašalj - otežano disanje
English: Rats in the high dose group experienced infusion-related reactions that were exacerbated by anaesthesia.
Croatian: U skupini štakora koji su dobivali visoku dozu razvile su se infuzijske reakcije, koje je anestezija dodatno pogoršala.
English: No specific tissue distribution studies of anidulafungin have been done in humans.
Croatian: Nisu provedena posebna ispitivanja tkivne raspodjele anidulafungina u ljudi.
English: In the clinical trials the outcome for anidulafungin with C. parapsilosis was not statistically different from other species however, the use of echinocandins in candidaemia due to C. parapsilosis may not be regarded as therapy of first choice
Croatian: U kliničkim ispitivanjima ishod za anidulafungin kod C. parapsilosis nije bio statistički različit od drugih vrsta, međutim, primjena ehinokandina u kandidemiji izazvanoj s C. parapsilosis ne mora se smatrati terapijom prvog izbora EUCAST nije odredio granične koncentracije za anidulafungin nevezane za vrstu
English: Dose Number of vials of powder
Croatian: Doza Broj bočica s praškom
English: With the 200/100 mg daily dose regimen at an infusion rate of 1.1 mg/min, the steady state Cmax and trough concentrations (Cmin) could reach approximately 7 and 3 mg/l, respectively, with an average steady state AUC of approximately 110 mgh/l.
Croatian: Kod sheme doziranja 200/100 mg na dan i brzine infuzije od 1,1 mg/min, Cmax u stanju dinamičke ravnoteže iznosi 7 mg/l, a najniže koncentracije (Cmin) 3 mg/l, uz prosječni AUC u stanju dinamičke ravnoteže od približno 110 mg·h/l.
English: The successful global response rate at the End of Intravenous Treatment (primary endpoint) was 18/35 (51.4%) and 16/35 (45.7%) at the End of All Treatment.
Croatian: Stopa uspješnog općeg odgovora na kraju intravenskog liječenja (primarna mjera ishoda) iznosila je 18/35 (51,4%) odnosno 16/35 (45,7%) na kraju svih liječenja.
English: The successful global response rate at End of Intravenous Treatment (primary endpoint) was 26/46 (56.5%) and End of All Treatment was 24/46 (52.2%).
Croatian: Stopa uspješnog općeg odgovora na kraju intravenskog liječenja (primarna mjera ishoda) bila je 26/46 (56,5%) te na kraju svih liječenja bila je 24/46 (52,2%).
English: In multiple dose studies in rabbits with disseminated candidiasis and in mice with CNS candida infection, anidulafungin has been shown to reduce fungal burden in the brain.
Croatian: U ispitivanjima višestrukih doza u kunića s diseminiranom kandidijazom i u miševa s infekcijom središnjeg živčanog sustava prouzročenom Candidom, pokazalo se da je anidulafungin smanjio količinu gljivica u mozgu.
English: Specimens for fungal culture should be obtained prior to therapy.
Croatian: Prije terapije treba uzeti uzorke za kulturu gljivica.
English: Anidulafungin has shown fungicidal activity against Candida species and activity against regions of active cell growth of the hyphae of Aspergillus fumigatus.
Croatian: Anidulafungin je pokazao fungicidni učinak na vrstu Candida, a djeluje i na područja aktivnog rasta stanica hifa Aspergillus fumigatusa.
English: The successful global response rate at End of Intravenous Treatment and End of All Treatment were both 7/13 (53.8%) in the 13 patients with neutropenia assessed by investigators at baseline.
Croatian: Stopa uspješnog općeg odgovora na kraju intravenskog liječnja i na kraju svih liječenja bila je u oba slučaja 7/13 (53,8%) u 13 bolesnika s neutropenijom, koju su ispitivači procijenili prije početka liječenja.
English: Drug interaction studies were performed with anidulafungin and other medicinal products likely to be co-administered.
Croatian: Provedena su ispitivanja interakcija anidulafungina i drugih lijekova s kojima će se vjerojatno istovremeno primjenjivati.
English: Anidulafungin is not hepatically metabolised.
Croatian: Anidulafungin se ne metabolizira u jetri.
English: Total infusion volume
Croatian: Ukupni volumen infuzije
English: 30 mL Type 1 glass vial with an elastomeric stopper (butyl rubber with an inert polymer coating on the product contact surface and lubricant on the top surface for easier machinability, or alternatively bromobutyl rubber with a lubricant) and aluminium seal with flip-off cap.
Croatian: Bočica od stakla tipa 1 od 30 ml s elastomerskim čepom (od butilne gume s neaktivnom polimerskom prevlakom na dodirnoj površini sa lijekom te sredstvom za podmazivanje na vanjskoj površini čepa radi lakšeg rukovanja ili od brombutilne gume sa sredstvom za podmazivanje) te aluminijskim prstenom i „flip-off“ kapicom.
English: From a microbiological point of view, following good aseptic practices, the infusion solution can be utilized for up to 48 hours from preparation when stored at 25ºC.
Croatian: S mikrobiološkog stajališta, kod pridržavanja dobre aseptičke prakse, otopina za infuziju može se iskoristiti u roku od najviše 48 sata nakon pripreme ako se čuva na temperaturi od 25ºC.
English: The infusion solution may be stored at 25ºC for 48 hours or stored frozen for at least 72 hours.
Croatian: Otopina za infuziju može se čuvati na temperaturi od 25ºC tijekom 48 sati ili zamrznuta najmanje 72 sata.
English: Infusion-related adverse events have been reported with anidulafungin, including rash, urticaria, flushing, pruritus, dyspnoea, bronchospasm and hypotension.
Croatian: Zabilježene su reakcije povezane s infuzijom anidulafungina, uključujući osip, urtikariju, navale crvenila, svrbež, dispneju, bronhospazam i hipotenziju.
English: Infusion-related adverse reactions have been reported with anidulafungin in clinical studies, including rash, pruritus, dyspnoea, bronchospasm, hypotension (common events), flushing, hot flush, and urticaria (uncommon events), summarized in Table 1 (see section 4.4).
Croatian: Zabilježene su nuspojave povezane s infuzijom anidulafungina u kliničkim ispitivanjima uključujući osip, svrbež, dispneju, bronhospazam, hipotenziju (česti događaji), navale crvenila, navale vrućine i urtikarijske nuspojave (manje česti događaji), sažeto prikazane u tablici 1 (vidjeti dio 4.4).
English: Treatment was administered for at least 14 and not more than 42 days.
Croatian: Liječenje je trajalo najkraće 14, a najdulje 42 dana.
English: The most common sites of infection included the peritoneal cavity (54.3%; 70 of 129), hepatobiliary tract (7.0%; 9 of 129), pleural cavity (5.4%; 7 of 129) and kidney (3.1%; 4 of 129).
Croatian: Najčešća mjesta infekcije uključivala su peritonealnu šupljinu (54,3%; 70 od 129), hepatobilijarni trakt (7,0%; 9 od 129), pleuralnu šupljinu (5,4%; 7 od 129) i bubrege (3,1%; 4 od 129).
English: In vivo, the ring-opened product is subsequently converted to peptidic degradants and eliminated mainly through biliary excretion.
Croatian: In vivo se peptidni spoj s otvorenim prstenom postupno pretvara u razgradne spojeve peptida i kao takav uglavnom eliminira izlučivanjem putem žuči.
English: Each vial contains 100 mg anidulafungin.
Croatian: Jedna bočica sadrži 100 mg anidulafungina.
English: From a microbiological point of view, following good aseptic practices, the reconstituted solution can be utilized for up to 24 hours when stored at 25ºC.
Croatian: S mikrobiološkog stajališta, kod pridržavanja dobre aseptičke prakse, rekonstituirana otopina može se iskoristiti u roku od najviše 24 sata kad se čuva na temperaturi od 25ºC.
English: The most common pathogens isolated at baseline were C. tropicalis (12 patients), C. albicans (7 patients), C. glabrata (7 patients), C. krusei (7 patients), and C. parapsilosis (6 patients).
Croatian: Najčešći patogeni izolirani na početku bili su C. tropicalis (12 bolesnika), C. albicans (7 bolesnika), C. glabrata (7 bolesnika) i C. krusei (7 bolesnika) i C. parapsilosis (6 bolesnika).
English: - Disorder of blood clotting system - Flushing - Hot flush - Stomach pain - Hives - Pain at injection site
Croatian: - poremećaji sustava zgrušavanja krvi - navale crvenila - navale vrućine - bol u trbuhu - koprivnjača - bol na mjestu primjene injekcije
English: Anidulafungin is not a clinically relevant substrate, inducer, or inhibitor of cytochrome P450 isoenzymes.
Croatian: Anidulafungin nije klinički značajan supstrat, induktor niti inhibitor izoenzima citokroma P450.
English: After subsequent dilution, the solution is to be discarded if particulate matter or discoloration is identified.
Croatian: Nakon daljnjeg razrjeđenja, otopinu treba odbaciti ako se primijete čestice ili promjena boje.
English: No dose limiting toxicity was observed in a study of 10 healthy subjects administered a loading dose of 260 mg followed by 130 mg daily; 3 of the 10 subjects experienced transient, asymptomatic transaminase elevations (3 x Upper Limit of Normal (ULN)).
Croatian: U ispitivanju u 10 zdravih ispitanika kojima je primijenjena udarna doza od 260 mg nakon koje se nastavilo s dozom od 130 mg na dan, nije bila primijećena toksičnost koja ograničuje dozu; 3 od tih 10 ispitanika imalo je prolazna asimptomatska povišenja transaminaza ( 3 x iznad gornje granice normale).
English: Rats were dosed with anidulafungin at three dose levels and anaesthetised within one hour using a combination of ketamine and xylazine.
Croatian: Anidulafungin je primijenjen štakorima u tri različite doze, nakon čega su štakori anestezirani kombinacijom ketamina i ksilazina unutar sat vremena od primjene lijeka.
English: 3, WBC ≤ 500
Croatian: 3 ili broj leukocita ≤ 500
English: ECALTA is supplied as a box containing 1 vial of 100 mg powder for concentrate for solution for infusion.
Croatian: ECALTA se isporučuje u kutiji koja sadrži 1 bočicu sa 100 mg praška za koncentrat za otopinu za infuziju.
English: C. parapsilosis harbours an intrinsic alteration in the target gene, which is the likely mechanism for the higher MICs than with other Candida species.
Croatian: Nema dovoljno dokaza C. parapsilosis ima intrinzičnu promjenu u ciljnom genu, što je vjerojatni mehanizam za više minimalne inhibitorne koncentracije od onih za druge vrste iz roda Candida.
English: The most common pathogens isolated at baseline were C. tropicalis (34.8%; 16/46), C. krusei (19.6%; 9/46), C. parapsilosis (17.4%; 8/46), C. albicans (15.2%; 7/46), and C. glabrata (15.2%; 7/46).
Croatian: Najčešći patogeni izolirani na početku ispitivanja bili su C. tropicalis (34,8%; 16/46), C. krusei (19,6%; 9/46), C. parapsilosis (17,4%; 8/46), C. albicans (15,2%; 7/46) i C. glabrata (15,2%; 7/46).
English: Additional Data in Neutropenic Patients
Croatian: Dodatni podaci za bolesnike s neutropenijom
English: Ask your doctor or pharmacist for advice before taking ECALTA while breast-feeding.
Croatian: Obratite se svom liječniku ili ljekarniku za savjet prije nego uzmete lijek ECALTA za vrijeme dojenja.
English: Parenteral medicinal products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Croatian: Lijekove za parenteralnu primjenu treba vizualno pregledati prije primjene da ne sadrže čestice i da nisu promijenili boju, kad god to otopina i spremnik omogućuju.
English: Infusion volume
Croatian: Volumen infuzije
English: It is unknown whether anidulafungin is excreted in human milk.
Croatian: Nije poznato izlučuje li se anidulafungin u majčino mlijeko.
English: Patients were randomised to receive either anidulafungin (200 mg intravenous loading dose followed by 100 mg intravenous daily) or fluconazole (800 mg intravenous loading dose followed by 400 mg intravenous daily), and were stratified by APACHE II score (≤20 and >20) and the presence or absence of neutropaenia.
Croatian: Bolesnici su bili randomizirani tako da su primali anidulafungin (intravenski u udarnoj dozi od 200 mg, nakon koje je slijedila intravenska doza od 100 mg na dan) ili flukonazol (intravenski u udarnoj dozi od 800 mg, nakon koje je slijedila intravenska doza od 400 mg na dan) i pri tom su stratificirani prema APACHE II ocjenskoj ljestvici (20 i >20) i prisutnosti odnosno odsutnosti neutropenije.
English: Nevertheless, care should be taken when co-administering anidulafungin and anaesthetic agents.
Croatian: Ipak, potreban je oprez kad se anidulafungin primjenjuje istovremeno s anesteticima.
English: The most common pathogens isolated at baseline were C. tropicalis (4 anidulafungin, 0 caspofungin), C. parapsilosis (2 anidulafungin, 1 caspofungin), C. krusei (2 anidulafungin, 1 caspofungin), and C. ciferrii (2 anidulafungin, 0 caspofungin).
Croatian: Najčešći patogeni izolirani na početku bili su C. tropicalis (4 ih je primalo anidulafungin, nijedan kaspofungin), C. parapsilosis (2 su primala anidulafungin, 1 bolesnik primao je kaspofungin), C. crusei (2 su bolesnika primala anidulafungin, 1 bolesnik primao je kaspofungin) i C. ciferrii (2 su bolesnika primala anidulafungin, nijedan kaspofungin).
English: Chemical and physical in-use stability of the reconstituted solution has been demonstrated for 24 hours at 25ºC.
Croatian: Dokazana kemijska i fizikalna stabilnost rekonstituirane otopine je 24 sata na temperaturi od 25ºC.
English: The efficacy of anidulafungin in adult neutropenic patients (defined as absolute neutrophil count ≤ 500 cells/mm
Croatian: Djelotvornost anidulafungina kod odraslih bolesnika s neutropenijom (definirana kao apsolutni broj neutrofila ≤ 500 stanica/mm
English: Aseptically reconstitute each vial with 30 mL water for injections to provide a concentration of 3.33 mg/mL.
Croatian: Na aseptički način pripremite svaku bočicu s 30 ml vode za injekciju, kako biste dobili koncentraciju od 3,33 mg/ml.
English: (Cyprus Branch) Τηλ: +357 22 817690
Croatian: Τηλ: +357 22 817690
English: The efficacy of anidulafungin (200 mg intravenous loading dose followed by 100 mg intravenous daily) in adult patients with microbiologically confirmed deep tissue candidiasis was assessed in an analysis of pooled data from 5 prospective studies (1 comparative and 4 open-label).
Croatian: Djelotvornost anidulafungina (intravenska udarna doza od 200 mg nakon čega slijedi 100 mg intravenski jednom na dan) kod odraslih bolesnika s mikrobiološki potvrđenom kandidijazom dubokih tkiva procijenjena je u analizi udruženih podataka iz 5 prospektivnih ispitivanja (1 usporedno i 4 otvorena ispitivanja).
English: Hepatic metabolism of anidulafungin has not been observed.
Croatian: Nije primijećen metabolizam anidulafungina u jetri.
English: The concentration of anidulafungin in the brain was low (brain to plasma ratio of approximately 0.2) in uninfected adult and neonatal rats after a single dose.
Croatian: Koncentracija anidulafungina u mozgu nakon jednokratne primijene doze u neinficiranih odraslih i tek okoćenih štakora bila je niska (omjer koncentracije u mozgu i plazmi iznosio je približno 0,2).
English: It is unlikely that anidulafungin will have clinically relevant effects on the metabolism of drugs metabolised by cytochrome P450 isoenzymes.
Croatian: Anidulafungin najvjerojatnije nema klinički značajne učinke na metabolizam drugih lijekova koji se metaboliziraju putem izoenzima citokroma P450.
English: There were no adverse reactions in the low-dose animals in the presence or absence of anaesthesia, and no infusion-related reactions in the mid-dose group in the absence of anaesthesia.
Croatian: U skupini štakora koja je primala nisku dozu nije bilo nuspojava, bez obzira na anesteziju, kao što ih nije bilo niti u skupini koja je primala srednju dozu kad nije bilo anestezije.
English: Eligible patients received either anidulafungin (200 mg intravenous loading dose followed by 100 mg intravenous daily) or caspofungin (70 mg intravenous loading dose followed by 50 mg intravenous daily) (2:1 randomization).
Croatian: Podobni bolesnici primili su bilo anidulafungin (udarna doza od 200 mg intravenski nakon čega slijedi intravenska doza od 100 mg jednom na dan) ili kaspofungin (udarna doza od 70 mg intravenski nakon čega slijedi doza od 50 mg intravenski jednom na dan) (randomizacija u omjeru 2:1).
English: Mortality rates in both the anidulafungin and fluconazole arms are presented below in Table 4:
Croatian: Stope smrtnosti u obje skupine, u onoj koja je primala anidulafungin i onoj koja je primala flukonazol, prikazane su u tablici 4:
English: Infusion associated reactions are infrequent when the rate of anidulafungin infusion does not exceed 1.1 mg/min (see section 4.4).
Croatian: Reakcije povezane s infuzijom nisu česte kad brzina infuzije anidulafungina ne prelazi 1,1 mg/min (vidjeti dio 4.4).
English: Pharmacotherapeutic group: - Antimycotics for systemic use, other antimycotics for systemic use.ATC code: JO2AX06
Croatian: Farmakoterapijska skupina: - antimikotici za sustavnu primjenu, ostali antimikotici za sustavnu primjenu.
English: Common side effects (may affect up to 1 in 10 people) are:
Croatian: Česte nuspojave (mogu se javiti u do 1 na 10 osoba) su:
English: If either particulate matter or discolouration are identified, discard the solution.
Croatian: Ako primijetite čestice ili promjenu boje, otopinu odbacite.
English: EXP {MONTH - YYYY}
Croatian: Rok valjanosti (MJESEC - GGGG)
English: Infusion-related adverse events are infrequent when the rate of anidulafungin infusion does not exceed 1.1 mg/min (see section 4.8).
Croatian: Nuspojave povezane s infuzijom su rijetke kada brzina infuzije anidulafungina ne prelazi 1,1 mg/minuti (vidjeti dio 4.8).
English: Each vial of powder contains 100 mg anidulafungin.
Croatian: Jedna bočica s praškom sadrži 100 mg anidulafungina.
English: The reconstituted solution may be stored up to 25°C for up to 24 hours prior to further dilution.
Croatian: Rekonstituirana otopina može se čuvati na temperaturi do 25ºC najviše 24 sata prije daljnjeg razrjeđivanja.
English: It is recommended that ECALTA be administered at a rate of infusion that does not exceed 1.1 mg/min (equivalent to 1.4 mL/min when reconstituted and diluted per instructions).
Croatian: Preporučuje se primijeniti lijek ECALTA brzinom infuzije koja ne prelazi 1,1 mg/min (što odgovara 1,4 ml/min nakon rekonstitucije i razrjeđenja prema uputama).
English: C. albicans (63.8% anidulafungin, 59.3% fluconazole), followed by C. glabrata (15.7%, 25.4%), C. parapsilosis (10.2%, 13.6%) and C. tropicalis (11.8%, 9.3%) - with 20, 13 and 15 isolates of the last 3 species, respectively, in the anidulafungin group.
Croatian: Najčešće izolirane vrste na početku ispitivanja bile su: C. albicans (63,8% anidulafungin, 59,3% flukonazol), zatim C. glabrata (15,7%, 25,4%), C. parapsilosis (10,2%, 13,6%) i C. tropicalis (11,8%, 9,3%) - s 20, 13 i 15 izolata za svaki od posljednja 3 soja u skupini koja je primala anidulafungin.
English: The pharmacokinetics of anidulafungin in patients with fungal infections are similar to those observed in healthy subjects based on population pharmacokinetic analyses.
Croatian: Na temelju populacijske farmakokinetičke analize, farmakokinetika anidulafungina u bolesnika s gljivičnim infekcijama slična je onoj kod zdravih ispitanika.
English: - If you have any further questions, ask your doctor or pharmacist or nurse.
Croatian: - Ako imate dodatnih pitanja, obratite se liječniku ili ljekarniku ili medicinskoj sestri.
English: The most common pathogens isolated from a deep tissue site at baseline were C. albicans (64.3%; 83 of 129), C. glabrata (31.0%; 40 of 129), C. tropicalis (11.6%; 15 of 129), and C. krusei (5.4%; 7 of 129).
Croatian: Najčešći patogeni izolirani iz dubokog tkiva na početku ispitivanja bili su C. albicans (64,3%; 83 od 129), C. glabrata (31,0%; 40 of 129), C. tropicalis (11,6%; 15 od 129) i C. krusei (5,4%; 7 od 129).
English: Diarrhoea, Nausea
Croatian: Proljev, mučnina
English: Chemical and physical in-use stability of the infusion solution has been demonstrated for 48 hours at 25ºC.
Croatian: Dokazana kemijska i fizikalna stabilnost rekonstituirane otopine je 48 sati na temperaturi od 25ºC.
English: Dilution requirements for ECALTA administration
Croatian: Potrebno razrjeđenje za primjenu lijeka ECALTA
English: Uncommon side effects (may affect up to 1 in 100 people) are:
Croatian: Manje česte nuspojave (mogu se javiti u do 1 na 100 osoba) su:
English: The rate of infusion should not exceed 1.1 mg/min (equivalent to 1.4 mL/min when reconstituted and diluted per instructions).
Croatian: Brzina infuzije ne smije biti veća od 1,1 mg/min (što odgovara 1,4 ml/min kod rekonstitucije i razrjeđivanja prema uputama).
English: - The other ingredients are: fructose, mannitol, polysorbate 80, tartaric acid, sodium hydroxide
Croatian: - Pomoćne tvari su: fruktoza, manitol, polisorbat 80, tartaratna kiselina, natrijev hidroksid (za podešavanje pH), kloridna kiselina (za podešavanje pH)
English: cells/mm or classified by the investigator as neutropenic at baseline) with microbiologically confirmed invasive candidiasis was assessed in an analysis of pooled data from 5 prospective studies (1 comparative versus caspofungin and 4 open-label, non-comparative).
Croatian: 3 ili bolesnici klasificirani od strane ispitivača kao bolesnici s neutropenijom prije početka liječenja) s mikrobiološki potvrđenom invazivnom kandidijazom procijenjena je u analizi udruženih podataka iz pet prospektivnih ispitivanja (jedno usporedno naspram kaspofungina i 4 otvorena, neusporedna ispitivanja).
English: Flushing, hot flush
Croatian: Navale crvenila, navale vrućine
English: How to store ECALTA
Croatian: Kako čuvati lijek ECALTA
English: Total reconstituted volume
Croatian: Ukupni volumen rekonstituirano g lijeka
English: If you have any further questions on the use of this medicine, ask your doctor, or pharmacist or nurse.
Croatian: U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka, obratite se svom liječniku ili ljekarniku ili medicinskoj sestri.
English: The efficacy of anidulafungin (200 mg intravenous loading dose followed by 100 mg intravenous daily) was assessed in 35 adult neutropenic patients defined as absolute neutrophil count ≤ 500 cells/mm
Croatian: Djelotvornost anidulafungina (intravenska udarna doza od 200 mg nakon čega slijedi 100 mg intravenski jednom na dan) procijenjena je u 35 odraslih bolesnika s neutropenijom definiranom kao apsolutni broj neutrofila ≤ 500 stanica/mm
English: In the 4 open-label studies, a switch to oral azole therapy was permitted after at least 5 to 10 days of treatment with anidulafungin.
Croatian: U četiri otvorena ispitivanja, prebacivanje na peroralnu terapiju azolima bilo je dopušteno nakon najmanje 5 do 10 dana liječenja anidulafunginom.
English: The efficacy of anidulafungin (200 mg intravenous loading dose followed by 100 mg intravenous daily) in adult neutropenic patients (defined as absolute neutrophil count ≤ 500 cells/mm
Croatian: Djelotvornost anidulafungina (udarna intravenska doza od 200 mg nakon čega slijedi 100 mg intravenski jednom na dan) kod odraslih bolesnika s neutropenijom (definirana kao apsolutni broj neutrofila ≤ 500 stanica/mm
English: Table of Adverse Reactions System Organ
Croatian: Tablica 1. Tablica s nuspojavama Klasa organskih sustava
English: ECALTA 100 mg powder for concentrate for solution for infusion
Croatian: ECALTA 100 mg prašak za koncentrat za otopinu za infuziju
English: In clinically stable patients, a switch to oral azole therapy was permitted after at least 10 days of study treatment.
Croatian: Kod klinički stabilnih bolesnika prebacivanje na peroralnu terapiju azolima bilo je dopušteno nakon najmanje 10 dana primanja ispitivanog lijeka.