FrancophonIA/ELRC3.0 huggingface dataset:
English: - If you have any further questions, please ask your doctor or pharmacist.
Danish: Er De i tvivl, så spørg lægen eller på apoteket.
English: In adult patients, STAYVEER treatment should be initiated at a dose of 62.5 mg twice daily for 4 weeks and then increased to the maintenance dose of 125 mg twice daily.
Danish: Hos voksne patienter bør behandling med STAYVEER påbegyndes med en dosis på 62,5 mg to gange dagligt i 4 uger, hvorefter dosis forhøjes til en vedligeholdelsesdosis på 125 mg to gange dagligt.
English: It cannot be excluded that this may affect your ability to father a child. Talk to your doctor if you have any questions or concerns about this.
Danish: Det kan ikke udelukkes, at dette kan påvirke din evne til at gøre en kvinde gravid.
English: STAYVEER 62.5 mg film-coated tablets are orange-white, round film-coated tablets with “62,5” on one side.
Danish: STAYVEER 62,5 mg filmovertrukne tabletter er orange-hvide, runde filmovertrukne tabletter med ”62,5” på den ene side.
English: Blood tests for anaemia
Danish: Blodprøver for blodmangel
English: • Gastrooesophageal reflux disease (acid reflux)
Danish: • Tilbageløb af mavesyre til spiserøret (gastroøsofageal reflukssygdom)
English: STAYVEER 125 mg film-coated tablets Each film-coated tablet contains 125 mg bosentan (as monohydrate).
Danish: STAYVEER 125 mg filmovertrukne tabletter Hver filmovertrukket tablet indeholder 125 mg bosentan (som monohydrat).
English: STAYVEER 125 mg film-coated tablets Orange-white, oval, biconvex, film-coated tablets, embossed with “125” on one side.
Danish: STAYVEER 125 mg filmovertrukne tabletter Orange-hvide, ovale, bikonvekse, filmovertrukne tabletter, med “125” præget på den ene side.
English: Cartons contain 56 or 112 film coated tablets (STAYVEER 62.5 mg film-coated tablets).
Danish: Æsker indeholder 56 eller 112 filmovertrukne tabletter (STAYVEER 62,5 mg filmovertrukne tabletter).
English: For further information see sections 4.5 and 4.6.
Danish: 4.4, 4.5 og 4.6)
English: STAYVEER 62.5 mg tablets bosentan
Danish: STAYVEER 62,5 mg tabletter bosentan
English: Uncommon (may affect up to one in 100 people):
Danish: Ikke almindelige (kan forekomme hos op til 1 ud af 100 personer):
English: Liver dysfunction risk may also be increased when medicinal products that are inhibitors of the bile salt export pump, e.g., rifampicin, glibenclamide and cyclosporine A (see sections 4.3 and 4.5), are co-administered with bosentan, but limited data are available.
Danish: Risikoen for leverdysfunktion kan også øges, når der indgives lægemidler, som hæmmer galdesalteksportpumpen, f.eks. rifampicin, glibenclamid og ciclosporin (se pkt.
English: STAYVEER 125 mg film-coated tablets are orange-white, oval film-coated tablets with “125” on one side.
Danish: STAYVEER 125 mg filmovertrukne tabletter er orange-hvide, ovale filmovertrukne tabletter med ”125” på den ene side.
English: Liver cirrhosis, liver failure1
Danish: Levercirrose, leversvigt1
English: STAYVEER 125 mg tablets bosentan
Danish: STAYVEER 125 mg tabletter bosentan
English: Contents of the pack and other information What STAYVEER contains
Danish: Pakningsstørrelser og yderligere oplysninger STAYVEER indeholder
English: How to take STAYVEER
Danish: Sådan skal De tage STAYVEER
English: STAYVEER 62.5 mg film-coated tablets Orange-white, round, biconvex, film-coated tablets, embossed with “62,5” on one side.
Danish: STAYVEER 62,5 mg filmovertrukne tabletter Orange-hvide, runde, bikonvekse, filmovertrukne tabletter, med “62,5” præget på den ene side.
English: • Pregnancy (see sections 4.4 and 4.6)
Danish: 4.4 og 4.6)
English: A reduction in symptoms of PAH was observed with bosentan treatment.
Danish: Bosentan behandlingen reducerede symptomerne på PAH.
English: Nov _____
Danish: Nov _____ Apr ______ Aug ______ Dec _____
English: In the event of associated clinical symptoms of liver injury, i.e., nausea, vomiting, fever, abdominal pain, jaundice, unusual lethargy or fatigue, flu-like syndrome (arthralgia, myalgia, fever), treatment must be stopped and re-introduction of STAYVEER is not to be considered.
Danish: mavesmerter, gulsot, usædvanlig apati eller træthed, influenza-lignende syndrom (arthralgia, myalgia,
English: Appropriate precautions must be taken for women of childbearing potential (see sections 4.3, 4.4 and 4.6).
Danish: Der bør tages passende forholdsregler for kvinder i den fertile alder (se pkt.
English: Common (may affect up to one in 10 people):
Danish: Almindelige bivirkninger (kan forekomme hos op til 1 ud af 10 personer):
English: STAYVEER 62.5 mg film-coated tablets bosentan
Danish: STAYVEER 62,5 mg filmovertrukne tabletter bosentan
English: STAYVEER 125 mg film-coated tablets bosentan
Danish: STAYVEER 125 mg filmovertrukne tabletter bosentan
English: Each tablet contains 62.5 mg of bosentan (as monohydrate).
Danish: Hver tablet indeholder 62,5 mg bosentan (som monohydrat).
English: • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 • Moderate to severe hepatic impairment, i.e., Child-Pugh class B or C (see section 5.2)
Danish: • Moderat til stærkt nedsat leverfunktion, dvs. Child-Pugh klasse B eller C (se pkt.
English: Cartons contain 56 film-coated tablets (STAYVEER 125 mg film-coated tablets).
Danish: Æsker med 56 filmovertrukne tabletter (STAYVEER 125 mg filmovertrukne tabletter).
English: Oedema, fluid retention5
Danish: Ødem, væskeretention5
English: Each tablet contains 125 mg of bosentan (as monohydrate).
Danish: Hver tablet indeholder 125 mg bosentan (som monohydrat).
English: Each film-coated tablet contains 62.5 mg bosentan (as monohydrate)
Danish: Hver filmovertrukket tablet indeholder 62,5 mg bosentan (som monohydrat)
English: • One patient in the bosentan group had treatment failure (need for ECMO as per protocol definition), which was declared based on increasing Oxygenation Index values within 8 h after the first study drug dose.
Danish: • En patient i bosentangruppen fik konstateret behandlingssvigt (behov for EMCO iht.
English: Each film-coated tablet contains 125 mg bosentan (as monohydrate)
Danish: Hver filmovertrukket tablet indeholder 125 mg bosentan (som monohydrat)
English: STAYVEER is contraindicated in patients with moderate to severe liver dysfunction (see sections 4.3, 4.4 and 5.2).
Danish: STAYVEER er kontraindiceret til patienter med moderat til svært nedsat leverfunktion (se pkt.
English: No recommendation on a posology can be made (see sections 5.1 and 5.2).
Danish: 5.1 og 5.2).
English: Jun ______
Danish: Jan ______ Maj ______ Sep _____ Feb ______ Jun _____
English: During treatment with STAYVEER, your doctor will arrange for regular blood tests to check for changes in your liver function.
Danish: Derfor vil lægen regelmæssigt, mens De er i behandling med STAYVEER, tage blodprøver for at undersøge, om der sker ændringer i Deres leverfunktion.
English: ((Front cover))
Danish: ((Forside))
English: In the post-marketing period rare cases of unexplained hepatic cirrhosis were reported after prolonged therapy with STAYVEER in patients with multiple co-morbidities and therapies with medicinal products.
Danish: Hos patienter med flere andre sygdomme og i behandling med andre lægemidler har der i perioden efter markedsføring været rapporteret sjældne tilfælde af uforklarlig levercirrose efter langvarig behandling med STAYVEER.
English: Cartons contain 56 film-coated tablets (STAYVEER 62.5 mg film-coated tablets).
Danish: Æsker med 56 filmovertrukne tabletter (STAYVEER 62,5 mg filmovertrukne tabletter).
English: Breast-feeding
Danish: Glyceroldibehenat
English: Haemoglobin
Danish: Hæmoglobin
English: The treatment in adults is usually started for the first 4 weeks with 62.5 mg twice daily (morning and evening), from then your doctor will usually advise you to take a 125 mg tablet twice daily, depending on how you react to STAYVEER.
Danish: Derefter vil Deres læge sædvanligvis råde Dem til at tage en tablet à 125 mg to gange dagligt, afhængigt af hvordan De reagerer på STAYVEER.
English: Do not swallow the desiccant
Danish: Tørremidlet må ikke sluges
English: Glycerol dibehenate Magnesium stearate
Danish: Magnesiumstearat
English: Anaemia, haemoglobin decrease, (see section 4.4)
Danish: Anæmi, nedsat hæmoglobin (se pkt.
English: If any of these apply to you, tell your doctor.
Danish: Hvis De opdager et eller flere af disse tegn, skal De omgående fortælle det til Deres læge.
English: What STAYVEER is and what it is used for What you need to know before you take STAYVEER How to take STAYVEER
Danish: Det skal De vide, før De begynder at tage STAYVEER Sådan skal De tage STAYVEER Bivirkninger
English: FUTURE 3/Extension, elevations in liver aminotransferases ≥ 3 × ULN were observed in 2% of patients.
Danish: I den samlede analyse af 100 PAH-børn fra de ikke-kontrollerede pædiatriske studier FUTURE 1/2 og FUTURE 3/forlængelse blev der set stigning i leveraminotransferaser til ≥ 3 × ULN hos 2% af patienterne.
English: For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder.
Danish: Hvis De vil have yderligere oplysninger om STAYVEER, skal De henvende Dem til den lokale repræsentant:
English: No effect of bosentan on time to healing of digital ulcers was observed in either study.
Danish: Ingen af studierne påviste virkning af bosentan på ophelingen af fingersår.
English: The recommended dose is calculated using the patient's height and weight.
Danish: Den anbefalede dosis beregnes på baggrund af patientens højde og vægt.
English: It can also be used as a maintenance treatment in patients who have received a platinum-based chemotherapy.
Danish: Det kan desuden anvendes som vedligeholdelsesbehandling hos patienter, der har fået platinbaseret kemoterapi
English: The full EPAR for Pemetrexed Fresenius Kabi can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
Danish: Den fuldstændige EPAR og resuméet af risikostyringsplanen for Pemetrexed Fresenius Kabi findes på agenturets websted under: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
English: This is a summary of the European public assessment report (EPAR) for Pemetrexed Fresenius Kabi.
Danish: Dette dokument er et sammendrag af den europæiske offentlige vurderingsrapport (EPAR) for Pemetrexed Fresenius Kabi.
English: The Committee recommended that Pemetrexed Fresenius Kabi be approved for use in the EU.
Danish: Udvalget anbefalede, at Pemetrexed Fresenius Kabi godkendes til anvendelse i EU.
English: The Agency's Committee for Medicinal Products for Human Use (CHMP) concluded that, in accordance with EU requirements, Pemetrexed Fresenius Kabi has been shown to be comparable to Alimta.
Danish: Udvalget for Lægemidler til Mennesker (CHMP) konkluderede, at det i overensstemmelse med EU's krav er påvist, at Pemetrexed Fresenius Kabi er sammenligneligt med Alimta.
English: This means that Pemetrexed Fresenius Kabi is similar to a ‘reference medicine' already authorised in the European Union (EU) called Alimta.
Danish: Det betyder, at Pemetrexed Fresenius Kabi er identisk med et "referencelægemiddel", som allerede er godkendt i Den Europæiske Union (EU), og som hedder Alimta.
English: In the body, pemetrexed is converted into an active form that blocks the activity of the enzymes that are involved in producing ‘nucleotides' (the building blocks of DNA and RNA, the genetic material of cells).
Danish: I kroppen omdannes pemetrexed til en aktiv form, der blokerer de enzymer, der medvirker ved dannelsen af nukleotider (byggestenene i dna og rna, cellernes genetiske materiale).
English: No additional studies were needed as Pemetrexed Fresenius Kabi is a generic medicine that is given by infusion and contains the same active substance as the reference medicine, Alimta.
Danish: Der krævedes ingen supplerende undersøgelser, eftersom Pemetrexed Fresenius Kabi er et generisk lægemiddel, der indgives ved infusion og indeholder det samme aktive stof som referencelægemidlet Alimta.
English: Pemetrexed Fresenius Kabi is a cancer medicine used to treat two types of lung cancer:
Danish: Pemetrexed Fresenius Kabi er et kræftlægemiddel til behandling af to typer af lungekræft:
English: What measures are being taken to ensure the safe and effective use of Pemetrexed Fresenius Kabi?
Danish: Hvilke foranstaltninger træffes der for at sikre risikofri og effektiv anvendelse af Pemetrexed Fresenius Kabi?
English: The active substance in Pemetrexed Fresenius Kabi, pemetrexed, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells), which belongs to the group ‘antimetabolites'.
Danish: Det aktive stof i Pemetrexed Fresenius Kabi, pemetrexed, er et vævsgiftigt (cytotoksisk) lægemiddel (dvs. det dræber celler, der deler sig, såsom kræftceller) i gruppen "antimetabolitter".
English: It is not intended to provide practical advice on how to use Pemetrexed Fresenius Kabi.
Danish: Det er ikke en praktisk vejledning i, hvordan Pemetrexed Fresenius Kabi bør anvendes.
English: For more information about treatment with Pemetrexed Fresenius Kabi, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Danish: Hvis du ønsker yderligere oplysninger om behandling med Pemetrexed Fresenius Kabi, kan du læse indlægssedlen (også en del af denne EPAR) eller kontakte din læge eller dit apotek.
English: Pemetrexed Fresenius Kabi is a ‘generic medicine'.
Danish: Pemetrexed Fresenius Kabi er et "generisk lægemiddel".
English: Other information about Pemetrexed Fresenius Kabi
Danish: Andre oplysninger om Pemetrexed Fresenius Kabi
English: Because Pemetrexed Fresenius Kabi is a generic medicine, its benefits and risks are taken as being the same as the reference medicine's.
Danish: Da Pemetrexed Fresenius Kabi er et generisk lægemiddel, anses benefit/risk-forholdet for at være det samme som for referencelægemidlet.
English: Pemetrexed Fresenius Kabi contains the active substance pemetrexed.
Danish: Pemetrexed Fresenius Kabi indeholder det aktive stof pemetrexed.
English: For practical information about using Pemetrexed Fresenius Kabi, patients should read the package leaflet or contact their doctor or pharmacist.
Danish: Hvis du ønsker praktisk vejledning om anvendelsen af Pemetrexed Fresenius Kabi, kan du læse indlægssedlen eller kontakte din læge eller dit apotek.
English: What are the benefits and risks of Pemetrexed Fresenius Kabi?
Danish: Hvilken fordel og risiko er der forbundet med Pemetrexed Fresenius Kabi?
English: What is Pemetrexed Fresenius Kabi and what is it used for?
Danish: Hvad er Pemetrexed Fresenius Kabi, og hvad anvendes det til?
English: Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Pemetrexed Fresenius Kabi have been included in the summary of product characteristics and the package leaflet.
Danish: I produktresuméet og indlægssedlen er der indføjet anbefalinger og forholdsregler, som sundhedspersonale og patienter skal følge med henblik på sikker og effektiv anvendelse af Pemetrexed Fresenius Kabi.
English: To reduce side effects, patients should take a corticosteroid (a type of medicine that reduces inflammation) and folic acid (a type of vitamin), and receive injections of vitamin B12 during treatment with Pemetrexed Fresenius Kabi.
Danish: For at mindske bivirkningerne under behandlingen med Pemetrexed Fresenius Kabi bør patienten få binyrebarkhormon (en type lægemiddel, der mindsker inflammation), folsyre (en type vitamin) og indsprøjtninger med B12-vitamin.
English: When Pemetrexed Fresenius Kabi is given with cisplatin, an ‘anti-emetic' medicine (to prevent vomiting) and fluids (to prevent dehydration) should also be given before or after the cisplatin dose.
Danish: Når Pemetrexed Fresenius Kabi gives sammen med cisplatin, bør der desuden før og efter cisplatin gives medicin mod kvalme og opkastninger samt væsketilskud for at forhindre udtørring.
English: Pemetrexed Fresenius Kabi is available as a powder that is made up into a solution for infusion (drip) into a vein.
Danish: Pemetrexed Fresenius Kabi fås som et pulver, der efter opløsning indgives med drop (ved infusion i en vene).
English: Why is Pemetrexed Fresenius Kabi approved?
Danish: Hvorfor blev Pemetrexed Fresenius Kabi godkendt?
English: As a result, the active form of pemetrexed slows down the formation of DNA and RNA and prevents the cells from dividing and multiplying.
Danish: Dannelsen af dna og rna bremses derved af den aktive form af pemetrexed.
English: How is Pemetrexed Fresenius Kabi used?
Danish: Hvordan anvendes Pemetrexed Fresenius Kabi?
English: How has Pemetrexed Fresenius Kabi been studied?
Danish: Hvordan blev Pemetrexed Fresenius Kabi undersøgt?
English: How does Pemetrexed Fresenius Kabi work?
Danish: Hvordan virker Pemetrexed Fresenius Kabi?
English: This overview was last updated in 04-2019.
Danish: Denne oversigt blev sidst opdateret i 04-2019.
English: For adults with a weakened immune system (the body's natural defences), it is given for 10 days.
Danish: Hos voksne med et svækket immunsystem (kroppens naturlige forsvar) gives det i 10 dage.
English: Ebilfumin received a marketing authorisation valid throughout the EU on 22 May 2014.
Danish: Ebilfumin fik en markedsføringstilladelse med gyldighed i hele EU den 22. maj 2014.
English: This is generally done on a caseby-case basis.
Danish: Dette afgøres sædvanligvis i hvert enkelt tilfælde.
English: When the neuraminidases are blocked, the virus cannot spread.
Danish: Når neuraminidaserne blokeres, kan virusset ikke brede sig.
English: Further information on Ebilfumin can be found on the Agency's website: ema.europa.eu/medicines/human/EPAR/ebilfumin.
Danish: Yderligere information om Ebilfumin findes på agenturets websted under: ema.europa.eu/medicines/human/EPAR/ebilfumin.
English: Ebilfumin is available as capsules (30 mg, 45 mg, and 75 mg).
Danish: Ebilfumin fås som kapsler (30 mg, 45 mg og 75 mg).
English: Two medicines are bioequivalent when they produce the same levels of the active substance in the body and are therefore expected to have the same effect.
Danish: To lægemidler er bioækvivalente, når de giver de samme niveauer af det aktive stof i kroppen, og de forventes derfor at have samme virkning.
English: Other information about Ebilfumin
Danish: Andre oplysninger om Ebilfumin
English: For children who weigh less than 40 kg, the dose is calculated according to the child's weight.
Danish: Hos børn, der vejer mindre end 40 kg, beregnes dosen ud fra barnets vægt.
English: Ebilfumin does not replace flu vaccination, and its use should be based on official recommendations.
Danish: Ebilfumin er ikke en erstatning for influenzavaccination, og anvendelsen af lægemidlet skal være baseret på officielle anbefalinger.
English: For more information about using Ebilfumin, see the package leaflet or contact your doctor or pharmacist.
Danish: For mere information om brug af Ebilfumin, se indlægssedlen eller kontakt lægen eller apotekspersonalet.
English: As for all medicines, data on the use of Ebilfumin are continuously monitored.
Danish: Som for alle lægemidler bliver data vedrørende brug af Ebilfumin løbende overvåget.
English: When Ebilfumin is used during a flu epidemic, it is given for up to 6 weeks.
Danish: Når Ebilfumin anvendes under en influenzaepidemi, gives det i op til seks uger.
English: What are the benefits and risks of Ebilfumin?
Danish: Hvilke fordele og risici er der forbundet med Ebilfumin?
English: An overview of Ebilfumin and why it is authorised in the EU
Danish: En oversigt over Ebilfumin og hvorfor det er godkendt i EU
English: Side effects reported with Ebilfumin are carefully evaluated and any necessary action taken to protect patients.
Danish: Bivirkninger rapporteret for Ebilfumin vurderes omhyggeligt, og der foretages de nødvendige forholdsregler for at beskytte patienterne.
English: What measures are being taken to ensure the safe and effective use of Ebilfumin?
Danish: Hvilke foranstaltninger træffes der for at sikre risikofri og effektiv anvendelse af Ebilfumin?
English: As for every medicine, the company provided studies on the quality of Ebilfumin.
Danish: Som for alle lægemidler fremlagde virksomheden studier af kvaliteten af Ebilfumin.
English: Ebilfumin can also be used as preventative treatment in exceptional cases, for instance when the seasonal flu vaccine may not provide sufficient protection and when there is a pandemic (a global epidemic of flu).
Danish: Ebilfumin kan undtagelsesvis gennemføres som en forebyggende behandling, f.eks. når vaccinen mod sæsoninfluenza ikke er tilstrækkelig, og hvis der er en pandemi (en global influenzaepidemi).
English: Oseltamivir works on the neuraminidases of both influenza-A (the most common type) and influenza-B viruses.
Danish: Oseltamivir virker på neuraminidaserne både ved influenza A-virus (den mest almindelige type) og influenza B-virus.
English: Studies on the benefits and risks of the active substance in the authorised uses have already been carried out with the reference medicine, Tamiflu, and do not need to be repeated for Ebilfumin.
Danish: Der er allerede gennemført studier af fordelene og risiciene ved det aktive stof i de godkendte anvendelser med referencelægemidlet, Tamiflu, og det er ikke nødvendigt at gentage disse med Ebilfumin.
English: This means that Ebilfumin contains the same active substance and works in the same way as a ‘reference medicine' already authorised in the EU called Tamiflu.
Danish: Det betyder, at Ebilfumin indeholder det samme aktive stof og virker på samme måde som et "referencelægemiddel", der allerede er godkendt i EU, og som hedder Tamiflu.
English: The European Medicines Agency concluded that, in accordance with EU requirements, Ebilfumin has been shown to have comparable quality and to be bioequivalent to Tamiflu.
Danish: Det Europæiske Lægemiddelagentur konkluderede, at det i overensstemmelse med EU's krav er påvist, at Ebilfumin er af sammenlignelig kvalitet og er bioækvivalent med Tamiflu.
English: What is Ebilfumin and what is it used for?
Danish: Hvad er Ebilfumin, og hvad anvendes det til?
English: Ebilfumin contains the active substance oseltamivir.
Danish: Ebilfumin indeholder det aktive stof oseltamivir.
English: Why is Ebilfumin authorised in the EU?
Danish: Hvorfor blev Ebilfumin godkendt i EU?
English: Because Ebilfumin is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine's.
Danish: Da Ebilfumin er et generisk lægemiddel, som er bioækvivalent med referencelægemidlet, anses benefit/risk-forholdet for at være det samme som for referencelægemidlet.
English: The usual dose for adults and children weighing more than 40 kg is 75 mg given once a day for 10 days after contact with an infected person.
Danish: Den sædvanlige dosis for voksne og børn, der vejer over 40 kg, er 75 mg én gang dagligt i 10 dage efter kontakt med en smittet person.
English: The active substance in Ebilfumin, oseltamivir, acts on the flu virus, blocking some of the enzymes on its surface known as neuraminidases.
Danish: Det aktive stof i Ebilfumin, oseltamivir, virker specifikt på influenzavirusset ved at blokere visse enzymer på virussets overflade, der kaldes neuraminidaser.
English: Ebilfumin is an antiviral medicine used to treat or prevent influenza (flu).
Danish: Ebilfumin er et antiviralt lægemiddel, der anvendes til behandling eller forebyggelse af influenza.
English: • To treat flu, it can be used in adults and children (including full-term newborns) who have the symptoms of flu, when the flu virus is circulating in the community;
Danish: • Til behandling af influenza kan det anvendes hos voksne og børn (inklusive fuldbårne nyfødte) med symptomer på influenza, når der er influenzavirus i omløb i befolkningen.
English: The usual dose for adults and children weighing more than 40 kg is 75 mg given twice a day for 5 days.
Danish: Den sædvanlige dosis for voksne og børn, der vejer over 40 kg, er 75 mg to gange dagligt i 5 dage.