FrancophonIA/ELRC3.0 huggingface dataset:
English: Mycamine is used to treat fungal infections caused by fungal or yeast cells called Candida.
Croatian: Mycamine se primjenjuje za liječenje gljivičnih infekcija uzrokovanih stanicama gljivice ili plijesni koja se zove Candida.
English: There are currently insufficient data available for the use of micafungin in patients with severe hepatic impairment and its use is not recommended in these patients (see sections 4.4 and 5.2).
Croatian: Trenutno nema dovoljno dostupnih podataka o primjeni mikafungina u bolesnika s teškim oštećenjem funkcije jetre i njegova se primjena ne preporučuje u tih bolesnika (vidjeti dijelove 4.4
English: Cardiac disorders tachycardia, palpitations, bradycardia
Croatian: Srčani poremećaji tahikardija, palpitacije, bradikardija
English: ≥ 1/1,000 to < 1/100
Croatian: ≥ 1/1 000 do < 1/100
English: Micafungin is unlikely to have an effect on driving or using machines.
Croatian: Nije vjerojatno da će mikafungin imati utjecaj na upravljanje vozilima ili rad sa strojevima.
English: Efficacy findings were consistent, independent of the infective Candida species, primary site of infection and neutropenic status (see Table).
Croatian: neovisno o vrsti infektivne gljivice Candida, primarnom mjestu infekcije i neutropenijskom statusu (vidjeti tablicu).
English: The vial is for single use only.
Croatian: Bočica je namijenjena samo za jednokratnu primjenu.
English: After reconstitution and dilution, the solution should be administered by intravenous infusion over approximately 1 hour.
Croatian: Nakon rekonstitucije i razrjeđenja, otopinu treba primijeniti intravenskom infuzijom u trajanju od približno 1 sat.
English: The diluted infusion solution should be used immediately.
Croatian: Razrijeđenu otopinu za infuziju treba odmah primijeniti.
English: Hypersensitivity to the active substance, to other echinocandins or to any of the excipients listed in section 6.1.
Croatian: Preosjetljivost na djelatnu tvar, druge ehinokandine ili neku od pomoćnih tvari navedenih u dijelu 6.1.
English: If patients develop a rash they should be monitored closely and micafungin discontinued if lesions progress.
Croatian: Ako se u bolesnika razvije osip, potrebno ih je pažljivo nadzirati i prekinuti primjenu mikafungina u slučaju napredovanja lezija.
English: 1 mg/kg/day *If the patient's response is inadequate, e.g. persistence of cultures or if clinical condition does not improve, the dose may be increased to 200 mg/day in patients weighing > 40 kg or 4 mg/kg/day in patients ≤ 40 kg.
Croatian: 1 mg/kg na dan *Ako odgovor bolesnika nije adekvatan, npr. i dalje pozitivna kultura ili ako se kliničko stanje ne poboljša, doza se može povisiti na 200 mg na dan u bolesnika tjelesne težine > 40 kg ili 4 mg/kg na dan u bolesnika tjelesne težine ≤ 40 kg.
English: Micafungin has been shown to be metabolised to several compounds; of these M-1 (catechol form), M-2 (methoxy form of M-1) and M-5 (hydroxylation at the side chain) of micafungin have been detected in systemic circulation.
Croatian: Pokazalo se da se mikafungin metabolizira u nekoliko spojeva; od kojih su M-1 (kateholni oblik), M-2 (metoksi oblik M-1) i M-5 (hidroksilacija na postraničnom lancu) metaboliti otkriveni u sistemskoj cirkulaciji.
English: Five ml of sodium chloride 9 mg/ml (0.9%) solution for infusion or glucose 50 mg/ml (5%) solution for infusion (taken from a 100 ml bottle/bag) should be aseptically and slowly injected into each vial along the side of the inner wall.
Croatian: Pet ml otopine za infuziju natrijevog klorida od 9 mg/ml (0,9%) ili otopine za infuziju glukoze od 50 mg/ml (5%) (koji se uzmu iz boce/vrećice od 100 ml) treba aseptički i sporo ubrizgati u svaku bočicu niz unutarnju stranu stijenke.
English: Your doctor monitors your response and condition to determine what Mycamine treatment is needed.
Croatian: Liječnik će pratiti Vaš odgovor na liječenje i stanje kako bi odredio kakvo je liječenje Mycamineom potrebno.
English: The MAH shall ensure that prior to prescribing of the product prescribers will receive the prescriber checklist.
Croatian: Nositelj odobrenja će osigurati da, prije propisivanja lijeka, liječnici koji ga propisuju dobiju kontrolnu listu za propisivača.
English: In rats, long-term treatment with micafungin led to liver damage and subsequent liver tumours.
Croatian: U štakora je dugotrajno liječenje mikafunginom dovelo do oštećenja jetre i posljedičnih tumora jetre.
English: The development of foci of altered hepatocytes (FAH) and hepatocellular tumours in rats was dependent on both dose and duration of micafungin treatment.
Croatian: Razvoj žarišta promijenjenih hepatocita i hepatocelularnih tumora u štakora ovisio je kako o dozi, tako i o trajanju liječenja mikafunginom.
English: Psychiatric disorders insomnia, anxiety, confusion
Croatian: Psihijatrijski poremećaji nesanica, anksioznost, konfuzija
English: One abortion occurred in rabbits at 32 mg/kg/day.
Croatian: Jedan se pobačaj dogodio u kunića pri dozi od 32 mg/kg na dan.
English: Overall Treatment Success in the Per Protocol Set, Invasive Candidiasis Study Micafungin
Croatian: Ukupni uspjeh liječenja prema planu ispitivanja, Ispitivanje invazivne kandidijaze Mikafungin
English: The antifungal treatment should continue for at least one week after two sequential negative blood cultures have been obtained and after resolution of clinical signs and symptoms of infection.
Croatian: Antimikotičko liječenje treba se nastaviti još najmanje jedan tjedan nakon što se uzastopno dobiju dvije negativne hemokulture i nakon nestanka kliničkih znakova i simptoma infekcije.
English: Micafungin has no or negligible influence on the ability to drive or use machines.
Croatian: Mikafungin ne utječe ili zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
English: Pack size: packs of 1 vial.
Croatian: Veličina pakiranja: 1 bočica.
English: • To minimise the risk of adaptive regeneration and potentially subsequent liver tumour formation, early discontinuation in the presence of significant and persistent elevation of ALT/AST is recommended.
Croatian: • Da bi se smanjio rizik od adaptivne regeneracije i mogućnost posljedičnog stvaranja tumora jetre, preporučuje se rano prekinuti primjenu u prisutnosti značajno i stalno povišenih vrijednosti ALT/AST.
English: Mycamine contains no preservatives.
Croatian: Mycamine ne sadrži konzervanse.
English: ¶ Clinical efficacy was also observed (< 5 patients) in the following Candida species: C. guilliermondii, C. famata, C. lusitaniae, C. utilis, C. inconspicua and C. dubliniensis.
Croatian: C. guilliermondii, C. famata, C. lusitaniae, C. utilis, C. inconspicua i C. dubliniensis.
English: The safety and efficacy in children (including neonates) less than 4 months of age of doses of 4 and 10 mg/kg for the treatment of invasive candidiasis with CNS involvement has not been adequately established.
Croatian: Sigurnost i djelotvornost u djece (uključujući novorođenčad) mlađe od 4 mjeseca u dozama od 4 i 10 mg/kg za liječenje invazivne kandidijaze koja zahvaća SŽS nisu adekvatno ustanovljene.
English: • Patients should be carefully monitored for liver damage and for worsening of renal function.
Croatian: • Bolesnike treba pažljivo pratiti zbog mogućeg oštećenja jetre i pogoršanja funkcije bubrega.
English: Patients with renal impairment: Severe renal impairment (Glomerular Filtration Rate [GFR] < 30 ml/min) did not significantly affect the pharmacokinetics of micafungin.
Croatian: Bolesnici s oštećenjem funkcije bubrega: Teško oštećenje funkcije bubrega (brzina glomerularne filtracije < 30 ml/min) nije značajno utjecala na farmakokinetiku mikafungina.
English: No dose adjustment of micafungin is required based on gender or race.
Croatian: Nije potrebna prilagodba doze mikafungina prema spolu ili rasi.
English: In juvenile dogs, 39 weeks treatment did not induce lesions in the testis and epididymides in a dose dependent manner at the end of treatment but after a treatment free period of 13 weeks a dose dependent increase in these lesions were noted in the treated recovery groups.
Croatian: U mladih pasa, 39 tjedana liječenja nije izazvalo lezije testisa i epididimisa na način ovisan o dozi na kraju liječenja, ali nakon razdoblja bez liječenja od 13 tjedana zabilježeno je povećanje ovih lezija ovisno o dozi u liječenim skupinama.
English: Micafungin may have the potential to affect male fertility in humans.
Croatian: U ljudi, mikafungin može djelovati na plodnost u muškaraca.
English: What you need to know before you use Mycamine Do not use Mycamine
Croatian: Što morate znati prije nego počnete primjenjivati Mycamine
English: In a second 26-week study hyperplasia of transitional cells in the urinary bladder occurred with a much lower incidence.
Croatian: U drugom 26-tjednom ispitivanju, incidencija hiperplazije prijelaznog epitela u mokraćnom mjehuru bila je puno niža.
English: A sufficient number of vials of Mycamine must be reconstituted to obtain the required dose in mg (see table below).
Croatian: Mycaminea kako bi se dobila potrebna doza u mg (vidjeti tablicu niže).
English: The incidence of some adverse reactions (listed in the table below) was higher in paediatric patients than in adult patients.
Croatian: Incidencija nekih nuspojava (navedenih u tablici niže) bila je viša u pedijatrijskih bolesnika nego u odraslih bolesnika.
English: The most frequently reported adverse reactions were nausea (2.8%), blood alkaline phosphatase increased (2.7%), phlebitis (2.5%, primarily in HIV infected patients with peripheral lines), vomiting (2.5%), and aspartate aminotransferase increased (2.3%).
Croatian: Najčešće zabilježene nuspojave bile su mučnina (2,8%), povišena alkalna fosfataza u krvi (2,7%), flebitis (2,5%, primarno u bolesnika zaraženih HIV-om, s perifernim venskim putevima), povraćanje (2,5%) i povišena aspartat aminotransferaza (2,3%).
English: In adult dogs, atrophy of seminiferous tubules with vacuolation of the seminiferous epithelium and decreased sperm in the epididymides were noted after prolonged treatment (39 weeks) but not after 13 weeks of treatment.
Croatian: U odraslih su pasa bili zabilježeni atrofija seminifernih kanalića s vakuolizacijom seminifernog epitela i smanjenje sperme u epididimisu nakon produljenog liječenja (39 tjedana), ali ne nakon 13 tjedana liječenja.
English: Mycamine contains the active substance micafungin.
Croatian: Mycamine sadrži djelatnu tvar mikafungin.
English: Diluted infusion solution
Croatian: Razrijeđena otopina za infuziju
English: If you experience an allergic attack, or a severe skin reaction (e.g. blistering and peeling of the skin), you must inform your doctor or nurse immediately
Croatian: Ako dobijete alergijsku reakciju ili tešku kožnu reakciju (npr. stvaranje mjehura i guljenje kože),
English: PK/PD bridging study demonstrated dose-dependent penetration of micafungin into CNS with the minimum AUC of 170 µg*hr/L required to achieve maximum eradication of fungal burden in the CNS tissues.
Croatian: Farmakokinetičko/farmakodinamičko ispitivanje s premošćivanjem podataka pokazalo je penetraciju mikafungina u SŽS ovisnu o dozi s minimalnim AUC od 170 µg*hr/L potrebnim za postizanje maksimalnog iskorjenjivanja gljivičnog opterećenja iz tkiva SŽS-a.
English: Male rats treated intravenously for 9 weeks showed vacuolation of the epididymal ductal epithelial cells, increased epididymis weights and reduced number of sperm cells (by 15%), however, in studies of 13 and 26 weeks duration these changes did not occur.
Croatian: Mužjaci štakora liječeni intravenski tijekom 9 tjedana imali su vakuolizaciju epitelnih stanica kanalića epididimisa, povećanu težinu epididimisa i smanjen broj spermija (za 15%), međutim, u ispitivanjima u trajanju od 13 i 26 tjedana ove promjene nisu nastale.
English: Animal studies have shown excretion of micafungin in breast milk.
Croatian: Ispitivanja na životinjama pokazala su da se mikafungin izlučuje u mlijeko ženki tijekom laktacije.
English: Do not use Mycamine after the expiry date which is stated on the vial and on the carton.
Croatian: Mycamine se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na bočici i kutiji.
English: Please tell your doctor if you have severe liver problems (e.g. liver failure or hepatitis) or have had abnormal liver function tests.
Croatian: Obavijestite liječnika ako imate tešku bolest jetre (npr. zatajenje jetre ili hepatitis) ili imate poremećene nalaze pretraga jetrene funkcije.
English: Co-administration of micafungin and amphotericin B desoxycholate was associated with a 30% increase in amphotericin B desoxycholate exposure.
Croatian: Istodobna primjena mikafungina s amfotericin B dezoksikolatom bila je povezana s povećanjem izloženosti amfotericin B dezoksikolatu za 30%.
English: Use in adults, adolescents ≥ 16 years of age and elderly
Croatian: Primjena u odraslih, adolescenata u dobi od 16 ili više godina i starijih osoba
English: Repeated daily doses up to 8 mg/kg (maximum total dose 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity.
Croatian: U kliničkim su ispitivanjima u odraslih bolesnika primijenjene ponovljene dnevne doze do 8 mg/kg (maksimalna ukupna doza 896 mg) bez zabilježene toksičnosti koja limitira dozu.
English: Indication
Croatian: OZNAČIVANJE
English: Micafungin haemolysed rabbit blood in vitro.
Croatian: Mikafungin je hemolizirao krv kunića in vitro.
English: The majority of hepatic adverse reactions were mild and moderate.
Croatian: Jetrene su nuspojave većinom bile blage i umjerene.
English: Treatment of invasive candidiasis
Croatian: Liječenje invazivne kandidijaze
English: Cases of serious hepatic dysfunction occurred uncommonly (see section 4.4).
Croatian: Slučajevi ozbiljnog poremećaja funkcije jetre su bili manje česti (vidjeti dio 4.4).
English: In a study performed in patients with severe hepatic impairment (ChildPugh score 10-12) (n=8), lower plasma concentrations of micafungin and higher plasma concentrations of the hydroxide metabolite (M-5) were seen compared to healthy subjects (n=8).
Croatian: U ispitivanju provedenom u bolesnika s teškim oštećenjem funkcije jetre (Child-Pugh bodovi: 10-12) (n = 8), opažene su niže koncentracije mikafungina u plazmi i više koncentracije hidroksi-metabolita (M-5) u plazmi u usporedbi s onima u zdravih ispitanika (n = 8).
English: Mean weight-adjusted clearance in children less than 4 months of age is approximately 2.6-fold greater than older children (12-16 years) and 2.3-fold greater than in adults.
Croatian: 2,6 puta veća nego kod starije djece (12-16 godina) i 2,3 puta veća nego u odraslih.
English: The infusion bottle/bag should be gently inverted to disperse the diluted solution but NOT agitated in order to avoid foaming.
Croatian: Boca/vrećica za infuziju treba se nježno okrenuti tako da se razrijeđena otopina rasprši, ali se NE SMIJE mućkati da se ne stvori pjena.
English: No standard carcinogenicity studies have been conducted but the development of FAH was assessed in female rats after up to 20 and 18 months after cessation of a 3 and 6 month treatment, respectively.
Croatian: Nisu provedena standardna ispitivanja kancerogenosti, ali razvoj žarišta promijenjenih hepatocita procijenjen je u ženki štakora najviše 20 mjeseci nakon prestanka tromjesečnog liječenja te 18 mjeseci nakon prestanka šestomjesečnog liječenja.
English: Rare (may affect up to 1 in 1,000 people) - anaemia due to breakdown of red blood cells (haemolytic anaemia), breakdown of red blood cells (haemolysis)
Croatian: Rijetko (mogu se javiti u do 1 na 1000 ljudi) - anemija zbog raspada crvenih krvnih stanica (hemolitička anemija), raspad crvenih krvnih stanica
English: To minimise the risk of adaptive regeneration and potentially subsequent liver tumour formation, early discontinuation in the presence of significant and persistent elevation of ALT/AST is recommended.
Croatian: Da bi se smanjio rizik od adaptivne regeneracije i posljedičnog mogućeg nastanka tumora jetre, preporučuje se rano prekinuti primjenu ako su vrijednosti ALT/AST značajno ili neprekidno povišene.
English: However, patients should be informed that dizziness has been reported during treatment with micafungin (see section
Croatian: Ipak, potrebno je bolesnike informirati da je tijekom liječenja mikafunginom prijavljena omaglica (vidjeti dio 4.8).
English: Nervous system disorders headache somnolence, tremor, dizziness, dysgeusia
Croatian: Poremećaji živčanog sustava glavobolja somnolencija, tremor, omaglica, disgeuzija
English: In standard safety pharmacology tests, cardiovascular and histamine releasing effects of micafungin were evident and appeared to be time above threshold dependent.
Croatian: Standardna ispitivanja sigurnosne farmakologije pokazala su da mikafungin ima kardiovaskularne učinke i učinke na oslobađanje histamina za koje se činilo da ovise o trajanju koncentracije iznad granične vrijednosti.
English: The nature and incidence of adverse events were similar between treatment groups.
Croatian: Narav i incidencija nuspojava bile su slične u obje liječene skupine.
English: Injection-site reactions None of the injection-site adverse reactions were treatment limiting.
Croatian: Niti jedna nuspojava na mjestu primjene injekcije nije ograničila liječenje.
English: Additionally, paediatric patients < 1 year of age experienced about two times more often an increase in ALT, AST and AP than older paediatric patients (see section 4.4).
Croatian: Osim toga, povišenje ALT, AST i AP se javljalo oko dva puta češće u pedijatrijskih bolesnika u dobi do 1 godine nego u starijih pedijatrijskih bolesnika (vidjeti dio 4.4).
English: There was a fixed daily dose of 50 mg (1.0 mg/kg) for micafungin and 400 mg (8 mg/kg) for fluconazole.
Croatian: Fiksna dnevna doza mikafungina iznosila je 50 mg (1,0 mg/kg), a flukonazola 400 mg (8 mg/kg).
English: Co. Kerry
Croatian: Kerry
English: Patients should be closely monitored for worsening of renal function.
Croatian: Bolesnike treba pažljivo nadzirati zbog mogućeg pogoršanja funkcije bubrega.
English: It is not known whether micafungin is excreted in human breast milk.
Croatian: Nije poznato izlučuje li se mikafungin u majčino mlijeko u ljudi.
English: In some patients more severe hepatic dysfunction, hepatitis, or hepatic failure including fatal cases have been reported.
Croatian: U nekih su bolesnika zabilježeni teži poremećaji funkcije jetre, hepatitis ili zatajenje jetre uključujući slučajeve sa smrtnim ishodom.
English: The infusion bottle/bag containing the diluted infusion solution should be inserted into a closable opaque bag for protection from light.
Croatian: Bocu/vrećicu za infuziju koja sadrži razrijeđenu otopinu za infuziju treba umetnuti u neprozirnu vreću koja se može zatvoriti radi zaštite od svjetlosti.
English: Micafungin is highly protein-bound and not dialysable.
Croatian: Mikafungin je velikim dijelom vezan za proteine plazme i ne može se ukloniti dijalizom.
English: Your doctor monitors your response and condition to determine what dose of Mycamine is needed.
Croatian: Liječnik će pratiti Vaš odgovor na liječenje i stanje kako bi odredio potrebnu dozu Mycaminea.
English: Micafungin treatment should be conducted on a careful risk/benefit basis, particularly in patients having severe liver function impairment or chronic liver diseases known to represent preneoplastic conditions, such as advanced liver fibrosis, cirrhosis, viral hepatitis, neonatal liver disease or congenital enzyme defects, or receiving a concomitant therapy including hepatotoxic and/or genotoxic properties.
Croatian: Liječenje mikafunginom treba provesti na temelju pažljive procjene omjera rizika i koristi, osobito u bolesnika s teškim poremećajem funkcije jetre ili kroničnom bolešću jetre za koju je poznato da predstavlja preneoplastično stanje, kao što su uznapredovala jetrena fibroza, ciroza, virusni hepatitis, neonatalna jetrena bolest ili urođeni enzimski poremećaji, ili istodobno primanje terapije koja ima hepatotoksična i/ili genotoksična svojstva.
English: Metabolism and nutritional disorders hypokalaemia, hypomagnesaemia, hypocalcaemia hyponatraemia, hyperkalaemia, hypophosphataemia, anorexia
Croatian: Poremećaji metabolizma i prehrane hipokalemija, hipomagnezemija, hipokalcemija hiponatremija, hiperkalemija, hipofosfatemija, anoreksija
English: No dose adjustment is necessary for the elderly.
Croatian: Nije potrebna prilagodba doze u starijih bolesnika.
English: Patients with hepatic impairment: In a study performed in patients with moderate hepatic impairment (Child-Pugh score 7-9), (n=8), the pharmacokinetics of micafungin did not significantly differ from those in healthy subjects (n=8).
Croatian: Bolesnici s oštećenjem funkcije jetre: U ispitivanju provedenom u bolesnika s umjerenim oštećenjem funkcije jetre (Child-Pugh bodovi: 7-9), (n = 8), farmakokinetika mikafungina nije se značajno razlikovala od one u zdravih ispitanika (n = 8).
English: No dose adjustment is necessary in patients with mild or moderate hepatic impairment (see section 5.2).
Croatian: Nije potrebna prilagodba doze u bolesnika s blagim ili umjerenim oštećenjem funkcije jetre (vidjeti dio 5.2).
English: However some people may feel dizzy when taking this medicine and if this happens to you, do not drive or use any tools or machines.
Croatian: Ukoliko se to dogodi Vama, nemojte upravljati vozilom niti koristiti bilo kakav alat ili stroj.
English: Reconstituted concentrate in vial
Croatian: Rekonstituirani koncentrat u bočici
English: In order to protect the infusion bottle / bag containing the diluted infusion solution from light it should be inserted into a closable opaque bag.
Croatian: Radi zaštite od svjetlosti, bocu/vrećicu za infuziju koja sadrži otopinu za infuziju treba umetnuti u neprozirnu vrećicu koja se može zatvoriti.
English: • To prevent infection with Candida in patients who are having a bone-marrow transplant or who are expected to have a neutropenia (low levels of neutrophils, a type of white blood cell) for 10 days or more.
Croatian: • Za sprečavanje infekcije Candidom u bolesnika koji su podvrgnuti presađivanju koštane srži ili za koje se očekuje da će imati neutropeniju (niska razina neutrofila, vrsta bijelih krvnih stanica)
English: Therefore, unused reconstituted concentrate must be discarded immediately.
Croatian: Stoga, rekonstituirani koncentrat koji nije primijenjen, mora se odmah zbrinuti.
English: ≥ 1/10,000 to
Croatian: ≥ 1/10 000 do
English: Breakthrough Aspergillus infections were observed in 1 versus 7 patients, and proven or probable breakthrough Candida infections were observed in 4 versus 2 patients in the micafungin and fluconazole groups, respectively.
Croatian: Probojne infekcije prouzročene Aspergillusom bile su opažene u jednog bolesnika u skupini koja je primala mikafungin nasuprot 7 bolesnika u skupini koja je primala flukonazol, a dokazane ili vjerojatne probojne infekcije prouzročene Candidom bile su opažene u 4 bolesnika u skupini koja je primala mikafungin nasuprot 2 bolesnika u skupini koja je primala flukonazol.
English: 2 mg/kg/day *Micafungin dosed at 4 mg/kg in children less than 4 months approximates drug exposures achieved in adults receiving 100 mg/day for the treatment of invasive candidiasis.
Croatian: *Mikafungin u dozi od 4 mg/kg kod djece mlađe od 4 mjeseca aproksimira izloženost lijeku postignutu kod odraslih osoba koje primaju 100 mg/dan za liječenje invazivne kandidijaze.
English: Drug interaction studies in healthy human subjects were conducted to evaluate the potential for interaction between micafungin and mycophenolate mofetil, ciclosporin, tacrolimus, prednisolone, sirolimus, nifedipine, fluconazole, ritonavir, rifampicin, itraconazole, voriconazole and amphotericin B. In these studies, no evidence of altered pharmacokinetics of micafungin was observed.
Croatian: Provedena su ispitivanja interakcija lijekova u zdravih ispitanika kako bi se procijenila mogućnost interakcija mikafungina i mofetilmikofenolata, ciklosporina, takrolimusa, prednizolona, sirolimusa, nifedipina, flukonazola, ritonavira, rifampicina, itrakonazola, vorikonazola i amfotericina B.
English: Investigations blood lactate dehydrogenase increased
Croatian: Pretrage povišena laktat dehidrogenaza u krvi