FrancophonIA/ELRC3.0 huggingface dataset:
English: There were no apparent trends toward a greater frequency of haemorrhagic adverse effects in patients taking cilostazol and ASA compared to patients taking placebo and equivalent doses of ASA.
Slovenian: Očitnega trenda večje pogostnosti hemoragičnih neželenih učinkov pri bolnikih, ki so jemali cilostazol in ASK, v primerjavi z bolniki, ki so jemali placebo in enakovredne odmerke ASK, ni bilo.
English: During treatment with <Cilostazol-containing medicinal product> make sure that
Slovenian: Med zdravljenjem z <zdravilom, ki vsebuje cilostazol>, se prepričajte, da
English: Administration of a single dose of 100 mg cilostazol with 240 ml grapefruit juice (an inhibitor of intestinal CYP3A4) did not have a notable effect on the pharmacokinetics of cilostazol.
Slovenian: Dajanje enega odmerka 100 mg cilostazola z 240 ml soka grenivke (zaviralec črevesnega CYP3A4) ni imelo opaznih učinkov na farmakokinetiko cilostazola.
English: There are no special dosage requirements for the elderly.
Slovenian: Za starejše bolnike ni posebnih zahtev glede odmerjanja.
English: If you forget to take <Cilostazol-containing medicinal product> If you miss a dose, do not worry; wait until the next dose to take your next tablet and then carry on as normal.
Slovenian: Če izpustite odmerek, ne skrbite; počakajte, da je čas za naslednji odmerek in vzemite naslednjo tableto, nato pa nadaljujte, kot običajno.
English: There are two major metabolites, a dehydro-cilostazol and a 4'-trans-hydroxy cilostazol, both of which have similar apparent half-lives.
Slovenian: Obstajata dva glavna presnovka, dehidrocilostazol in 4'-trans-hidroksi cilostazol, ki imata podobna navidezna razpolovna časa.
English: The inhibition is effective against a range of aggregants (including shear stress, arachidonic acid, collagen, ADP and adrenaline); in man the inhibition lasts for up to 12 hours, and on cessation of administration of cilostazol recovery of aggregation occurred within 48-96 hours, without rebound hyperaggregability.
Slovenian: Zaviranje učinkuje proti vrsti agregantov (vključno s strižno napetostjo, arahidonsko kislino, kolagenom, ADP in adrenalinom); pri ljudeh traja zaviranje do 12 ur, po prekinitvi dajanja cilostazol pa je okrevanje agregacije nastopilo v 48-96 urah, brez povratne hiperagregabilnosti.
English: Taking cilostazol with food has been shown to increase the maximum plasma concentrations (Cmax) of cilostazol, which may be associated with an increased frequency of adverse reactions.
Slovenian: Pokazalo se je, da jemanje cilostazola s hrano poveča največje koncentracije (Cmax) cilostazola v plazmi, kar je lahko povezano s povečano pogostnostjo neželenih reakcij.
English: If you take more <Cilostazol-containing medicinal product> than you should If for any reason you have taken more <Cilostazol-containing medicinal product> tablets than you should, you may have signs and symptoms such as severe headache, diarrhoea, a fall in blood pressure and irregularities of your heartbeat.
Slovenian: Če zaradi katerega koli razloga vzamete večji odmerek <zdravila, ki vsebuje cilostazol>, tablete, kot bi smeli, se bodo morda pojavili znaki in simptomi, kot so hud glavobol, driska, padec krvnega tlaka in nereden srčni utrip.
English: Concomitant administration of cilostazol and clopidogrel did not have any effect on platelet count, prothrombin time (PT) or activated partial thromboplastin time (aPTT).
Slovenian: Sočasno dajanje cilostazola in klopidogrela ni vplivalo na število trombocitov, protrombinski čas (PT) ali aktivirani delni tromboplastinski čas (aPTT).
English: Patients should be warned to report any episode of bleeding or easy bruising whilst on therapy.
Slovenian: Bolnike je treba opozoriti, da morajo sporočiti vse epizode krvavitve ali hitrega nastajanja modric med zdravljenjem.
English: Cilostazol may cause dizziness and patients should be warned to exercise caution before they drive or operate machinery.
Slovenian: Cilostazol lahko povzroči omotico, zato je treba bolnike opozoriti, da so med vožnjo ali upravljanjem s stroji previdni.
English: Do not use <Cilostazol-containing medicinal product> after the expiry date which is stated on the carton and blister after "EXP".
Slovenian: <Zdravila, ki vsebuje cilostazol>, ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in pretisnemu omotu poleg oznake "EXP".
English: In case of retinal bleeding administration of cilostazol should be stopped.
Slovenian: V primeru retinalne krvavitve je treba z uporabo cilostazola prenehati.
English: • If you need to have surgery including having teeth removed, tell your doctor or dentist that you are taking <Cilostazol-containing medicinal product>.
Slovenian: • Če vam morajo operativno odstraniti zobe, povejte svojemu zdravniku ali zobozdravniku, da jemljete <zdravilo, ki vsebuje cilostazol>.
English: In in vitro tests on Chinese ovary hamster cells cilostazol produced a weak but significant increase in chromosome aberration frequency.
Slovenian: V testih in vitro s celicami jajčnika kitajskega hrčka je cilostazol povzročil šibko, a značilno zvišanje pogostnostjo kromosomske aberacije.
English: If you are not sure if this applies to your medicines ask your doctor or pharmacist.
Slovenian: Če niste prepričani, ali kaj od tega velja za vaša zdravila, se posvetujte s svojim zdravnikom ali farmacevtom.
English: Your medicine is supplied in packs of 14, 20, 28, 30, 50, 56, 98, 100, 112 or 168 tablets or hospital packs with 70 (5x14) tablets.
Slovenian: Zdravilo je na voljo v pakiranjih po 14, 20, 28, 30, 50, 56, 98, 100, 112 ali 168 tablet ali bolnišničnih pakiranjih s 70 (5x14) tabletami.
English: The signs and symptoms can be anticipated to be severe headache, diarrhoea, tachycardia and possibly cardiac arrhythmias.
Slovenian: Pričakovani znaki in simptomi so hud glavobol, driska, tahikardija in možne srčne aritmije.
English: Cartons containing 14, 20, 28, 30, 50, 56, 98, 100, 112 and 168 tablets as well as hospital packs with 70 (5x14) tablets packed in PVC/Aluminium blisters.
Slovenian: Škatla, ki vsebuje 14, 20, 28, 30, 50, 56, 98, 100, 112 in 168 tablet ter bolnišnično pakiranje s 70 (5x14) tabletami, pakirano v pretisne omote iz PVC/aluminija.
English: Mutagenicity studies were negative in bacterial gene mutation, bacterial DNA repair, mammalian cell gene mutation and mouse in vivo bone marrow chromosomal aberrations.
Slovenian: Študije mutagenosti so bile negativne za mutacijo gena bakterije, popravljanja bakterijske DNA, genske mutacije v celicah sesalcev in kromosomske aberacije kostnega mozga pri miši in vivo.
English: Clopidogrel and other antiplatelet drugs
Slovenian: Klopidogrel in druga antiagregacijska zdravila
English: Animal studies have shown cilostazol to have vasodilator effects and this has been demonstrated in small studies in man where ankle blood flow was measured by strain gauge plethysmography.
Slovenian: Študije na živalih so pokazale, da ima cilostazol vazodilatatorski učinek, kar so ugotovili v majhnih študijah pri ljudeh, kjer so pretok krvi v gležnju izmerili s pletizmografijo z merilnimi lističi.
English: It has several actions which include widening of some blood vessels and reducing the clotting activity (clumping) of some blood cells called platelets inside your vessels.
Slovenian: Deluje na več načinov, med drugim širi nekatere krvne žile in zmanjša koagulacijo (zlepljanje) nekaterih krvnih celic, imenovanih trombociti, v vaših žilah.
English: Cilostazol and several of its metabolites are phosphodiesterase III inhibitors which suppress cyclic AMP degradation, resulting in increased cAMP in a variety of tissues including platelets and blood vessels.
Slovenian: Cilostazol in številni njegovi presnovki so zaviralci fosfodiesteraze III, ki zavira razgradnjo cikličnega AMP, kar povzroči povečanje cAMP pri različnih tkivih, vključno s trombociti in krvnimi žilami.
English: • Diuretics (e.g., hydrochlorothiazide, furosemide)
Slovenian: • diuretike (npr. hidroklorotiazid, furosemid)
English: Plasma concentrations (as measured by AUC) of the dehydro and 4`-trans-hydroxy metabolites are ~41% and ~12% of cilostazol concentrations.
Slovenian: Koncentracije v plazmi (izmerjeno z AUC) za presnovka dehidro in 4`-trans-hisdroksi sta ~41 % in ~12 % koncentracij cilostazola.
English: Cilostazol should be initiated by physicians experienced in the management of intermittent claudication (see also section 4.4).
Slovenian: Zdravljenje s cilostazolom mora uvesti zdravnik z izkušnjami pri zdravljenju intermitentne klavdikacije (glejte tudi poglavje 4.4).
English: • If you experience easy bruising or bleeding, stop taking <Cilostazol-containing medicinal product> and tell your doctor.
Slovenian: • Če hitro dobite modrice ali začnete krvaveti, prenehajte jemati <zdravilo, ki vsebuje cilostazol>, in to povejte svojemu zdravniku.
English: • angiotensin II receptor blockers (e.g., valsartan, candesartan)
Slovenian: • zaviralce receptorja angiotenzina II (npr. valsartan, kandesartan)
English: Patients with any history of ventricular tachycardia, ventricular fibrillation or multifocal ventricular ectopics, whether or not adequately treated, and in patients with prolongation of the QTc interval
Slovenian: • bolniki z ventrikularno tahikardijo, ventrikularno fibrilacijo ali multifokalno ventrikularno ektopijo v anamnezi, z ustreznim zdravljenjem ali brez njega, in bolniki s podaljšanim intervalom QTc
English: In subjects with severe renal impairment, the free fraction of cilostazol was 27% higher and both Cmax and AUC were 29% and 39% lower respectively than in subjects with normal renal function.
Slovenian: Pri osebah s hudo okvaro delovanja ledvic je bila prosta frakcija cilostazola 27 % višja, Cmax in AUC pa sta bila 29 % oz. 39 % nižja kot pri osebah z normalnim delovanjem ledvic.
English: You have been prescribed <Cilostazol-containing medicinal product> for "intermittent claudication".
Slovenian: <Zdravilo, ki vsebuje cilostazol>, vam je bilo predpisano za "intermitentno klavdikacijo".
English: • acetylsalicylic acid
Slovenian: • acetilsalicilno kislino
English: Patients receiving treatment with cilostazol should continue with their life-style modifications (smoking cessation and exercise), and pharmacological interventions (such as lipid lowering and antiplatelet treatment) to reduce the risk of cardiovascular events.
Slovenian: Bolniki, ki se zdravijo s cilostazolom, naj spremembe svojega življenjskega sloga izvajajo še naprej (prenehanje kajenja in vadba) in nadaljujejo s farmakološkimi ukrepi (kot je zdravljenje z zdravili za zmanjšanje maščob in z protitrombocitnimi zdravili), da zmanjšajo tveganje za nastanek kardiovaskularnih dogodkov.
English: The antiplatelet effect may theoretically be altered and should be carefully monitored when cilostazol is co-administered with CYP3A4 and CYP2C19 inducers.
Slovenian: Antiagregacijski učinek se lahko teoretično spremeni in ga je treba skrbno spremljati pri sočasnem dajanju cilostazola z induktorji CYP3A4 in CYP2C19.
English: <Cilostazol-containing medicinal product> is for second-line use, in patients in whom lifestyle modifications (including stopping smoking and [supervised] exercise programs) and other appropriate interventions have failed to sufficiently improve their intermittent claudication symptoms.
Slovenian: <Zdravilo, ki vsebuje cilostazol> je za uporabo kot druga izbira zdravljenja pri bolnikih, pri katerih sprememba življenjskega sloga (vključno s prenehanjem kajenja in [nadziranimi] programi vadbe) in drugi ustrezni posegi niso ustrezno izboljšali njihovih simptomov intermitentne klavdikacije.
English: The Cmax of cilostazol and its primary circulating metabolites increase less than proportionally with increasing doses.
Slovenian: Cmax za cilostazol in njegove primarne presnovke v obtoku se je z večanjem odmerka povečal manj kot sorazmerno.
English: increases in mean ACD ranged from 60.4 - 129.1 metres, whilst mean ICD increases ranged from 47.3 - 93.6 metres.
Slovenian: Po 24 tednih zdravljenja je cilostazol 100 mg dvakrat na dan zvišal povprečni razpon ACD med 60,4 do 129,1 metri, povprečni razpon ICD pa se je povečal za med 47,3 do 93,6 metri.
English: Most patients recovered on discontinuation of cilostazol.
Slovenian: Večina bolnikov je po prekinitvi uporabe cilostazola okrevala.
English: There have been rare or very rare reports of haematological abnormalities including thrombocytopenia, leucopenia, agranulocytosis, pancytopenia and aplastic anaemia (see section 4.8).
Slovenian: Obstajajo redka ali zelo redka poročila o hematoloških nepravilnostih, vključno s trombocitopenijo, levkopenijo, agranulocitozo, pancitopenijo in aplastično anemijo (glejte poglavje 4.8).
English: The usual dose is two 50 mg tablets twice a day (morning and evening).
Slovenian: • Priporočeni odmerek je dve tableti 50 mg dvakrat na dan (zjutraj in zvečer).
English: If you have any further questions, please ask your doctor or your pharmacist.
Slovenian: - Če imate dodatna vprašanja, se posvetujte z zdravnikom ali farmacevtom.
English: WHAT <CILOSTAZOL-CONTAINING MEDICINAL PRODUCT> IS AND WHAT IT IS USED FOR
Slovenian: Kaj je <zdravilo, ki vsebuje cilostazol>, in za kaj ga uporabljamo
English: However, your doctor may prescribe a lower dose if you are taking other medicines which may have an effect on <Cilostazol-containing medicinal product>.
Slovenian: Vendar pa vam lahko zdravnik predpiše manjši odmerek, če jemljete druga zdravila, ki lahko vplivajo na učinek <zdravila, ki vsebuje cilostazol>.
English: Based on its mechanism of action, cilostazol may induce tachycardia, palpitation, tachyarrhythmia and/or hypotension.
Slovenian: Na podlagi mehanizma delovanja lahko cilostazol povzroči tahikardijo, palpitacije, tahiaritmijo in/ali hipotenzijo.
English: However, the AUC for cilostazol and its metabolites increase approximately proportionately with dose.
Slovenian: Vendar pa se AUC za cilostazol in njegove presnovke poveča približno sorazmerno z odmerkom.
English: Driving and using machines <Cilostazol-containing medicinal product> may cause dizziness.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev <Zdravilo, ki vsebuje cilostazol>, lahko povzroči omotico.
English: Caution is needed when co-administering cilostazol with any other agent which has the potential to reduce blood pressure due to the possibility that there may be an additive hypotensive effect with a reflex tachycardia.
Slovenian: Previdnost je potrebna pri sočasni uporabi cilostazola z drugimi zdravili, ki lahko zmanjšajo krvni tlak, saj obstaja možnost aditivnega hipotenzivnega učinka z refleksno tahikardijo.
English: The usual dose is one 100 mg tablet twice a day (morning and evening).
Slovenian: • Priporočeni odmerek je ena tableta 100 mg dvakrat na dan (zjutraj in zvečer).
English: What <Cilostazol-containing medicinal product> is and what it is used for Before you take <Cilostazol-containing medicinal product> How to take <Cilostazol-containing medicinal product> Possible side effects
Slovenian: Kaj je <zdravilo, ki vsebuje cilostazol>, in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli <zdravilo, ki vsebuje cilostazol> Kako jemati <zdravilo, ki vsebuje cilostazol> Možni neželeni učinki
English: An increase in the frequency of diarrhoea and palpitation has been found in patients older than 70 years.
Slovenian: Pri bolnikih, starejših kot 70 let, so opazili povečanje pogostnosti driske in palpitacij.
English: A meta-analysis based on weighted mean differences across the nine studies indicated that there was a significant absolute overall post-baseline improvement of 42 m in maximal walking distance (ACD) for cilostazol 100 mg b.i.d.
Slovenian: Metaanaliza na podlagi uteženih povprečnih razlik v devetih študijah je pokazala obstoj značilnega absolutnega splošnega izboljšanja po izhodišču 42 m pri najdaljši prehojeni razdalji (ACD) za cilostazol 100 mg dvakrat na dan glede na izboljšanje s placebom.
English: The effect of CYP3A4 and CYP2C19 inducers (such as carbamazepine, phenytoin, rifampicin and St. John's wort) on cilostazol pharmacokinetics has not been evaluated.
Slovenian: Učinka induktorjev CYP3A4 in CYP2C19 (kot so karbamazepin, fenitoin, rifampicin in šentjanževka) na farmakokinetiko cilostazol niso ovrednotili.
English: • calcium channel blockers (e.g., verapamil, amlodipine)
Slovenian: • zaviralce kalcijevih kanalčkov (npr. verapamil, amlodipin)
English: The dehydro metabolite is 4-7 times as active a platelet antiaggregant as the parent compound and the 4'-trans-hydroxy metabolite is one fifth as active.
Slovenian: Presnovek dehidro je 4-7-krat tako aktiven zaviralec agregacije trombocitov kot osnovna spojina, presnovek 4'trans-hidroksi pa je eno petino tako aktiven.
English: Short term (4 days) co-administration of ASA with cilostazol suggested a 23-25% increase in inhibition of ADP-induced ex vivo platelet aggregation when compared to ASA alone.
Slovenian: Kratkotrajno ( 4 dni) sočasno dajanje ASK s cilostazolom je pokazalo 23-25 % zvišanje zaviranja agregacije trombocitov ex vivo zaradi ADP v primerjavi s samo ASK.
English: Taking <Cilostazol-containing medicinal product> with food and drink <Cilostazol-containing medicinal product> tablets should be taken 30 minutes before breakfast and the evening meal.
Slovenian: <Zdravilo, ki vsebuje cilostazol>, skupaj s hrano in pijačo <Zdravilo, ki vsebuje cilostazol>, tablete, morate vzeti 30 minut pred zajtrkom in večerjo.
English: No unusual neoplastic outcomes were observed in two-year carcinogenicity studies in rats at oral (dietary) doses up to 500 mg/kg/day, and in mice at doses up to 1000 mg/kg/day.
Slovenian: V dveletnih študijah kancerogenosti pri podganah s peroralnimi (s hrano) odmerki do 500 mg/kg/dan in pri miših z odmerki do 1.000 mg/kg/dan niso opazili neobičajnih neoplastičnih izidov.
English: Caution should be exercised when prescribing cilostazol for patients with atrial or ventricular ectopy and patients with atrial fibrillation or flutter.
Slovenian: Pri predpisovanju cilostazola bolnikom z atrijsko ali ventrikularno ektopijo in bolnikom z atrijsko fibrilacijo ali undulacijo je potrebna previdnost.
English: Therefore, drugs inhibiting CYP3A4 (e.g., some macrolides, azole antifungals, protease inhibitors) or CYP2C19 (like proton pump inhibitors, PPIs) increase the total pharmacological activity and could have the potential to enhance the undesirable effects of cilostazol.
Slovenian: Zato zdravila, ki zavirajo CYP3A4 (npr. nekateri makrolidi, azolni antimikotiki, zaviralci proteaze) ali CYP2C19 (kot so zaviralci protonske črpalke) povečajo skupno farmakološko aktivnost in lahko pospešijo neželene učinke cilostazola.
English: Like all medicines, <Cilostazol-containing medicinal product> can cause side effects, although not everybody gets them.
Slovenian: Kot vsa zdravila ima lahko tudi to zdravilo neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
English: The Cmax and AUC of the dehydro metabolite were 41% and 47% lower respectively in the severely renally impaired subjects compared to subjects with normal renal function.
Slovenian: Cmax in AUC presnovka dehidro sta bila 41 % oz. 47 % nižja pri osebah s hudo okvaro ledvic kot pri osebah normalnim delovanjem ledvic.
English: The medicine must not be administered to patients with a creatinine clearance <25ml/min (see section 4.3).
Slovenian: Bolniki s očistkom kreatinina < 25 ml/min zdravila ne smejo jemati (glejte poglavje 4.3).
English: In the case of patients receiving strong inhibitors for CYP3A4 or CYP2C19, plasma levels of cilostazol were shown to be increased.
Slovenian: Pokazalo se je, da se pri bolnikih, ki prejemajo močne zaviralce encimov CYP3A4 ali CYP2C19, ravni cilostazola v plazmi zvišajo.
English: At lower dose levels, retardations of ossification were observed.
Slovenian: Pri nižjih odmerkih so opazili zapoznelo okostenitev.
English: <Cilostazol-containing medicinal product> may do the same to other medicines.
Slovenian: Tudi <zdravilo, ki vsebuje cilostazol>, ima lahko enak učinek na nekatera zdravila.
English: Since cilostazol is extensively metabolised by hepatic enzymes, it is contraindicated in patients with moderate or severe hepatic impairment.
Slovenian: Ker cilostazol obširno presnovijo jetrni encimi, je kontraindiciran pri bolnikih z zmerno ali hudo okvaro jeter.
English: How to store <Cilostazol-containing medicinal product> Contents of the pack and other information
Slovenian: Shranjevanje <zdravila, ki vsebuje cilostazol> Vsebina pakiranja in dodatne informacije
English: The primary isoenzymes involved in its metabolism are cytochrome P-450 CYP3A4, to a lesser extent, CYP2C19, and to an even lesser extent CYP1A2.
Slovenian: Primarni izoencimi, ki sodelujejo pri presnovi, so citokrom P-450 CYP3A4, v manjšem obsegu CYP2C19 in v še manjšem obsegu CYP1A2.
English: A full blood count should be performed if infection is suspected or there is any other clinical evidence of blood dyscrasia.
Slovenian: Pri sumu na okužbo ali drugih kliničnih znakih diskrazije krvi je treba opraviti preiskavo celotne krvne slike.
English: Cilostazol is not a substitute for such treatments.
Slovenian: Cilostazol ni nadomestilo za ta zdravljenja.
English: Caution is advised in case of co-administration with statins metabolised by CYP3A4, for example simvastatin, atorvastatin and lovastatin.
Slovenian: Previdnost se priporoča tudi pri sočasnem dajanju s statini, ki jih presnavlja CYP3A4, na primer s simvastatinom, atorvastatinom in lovastatinom.
English: Cilostazol also inhibits smooth muscle cell proliferation in rat and human smooth muscle cells in vitro, and inhibits the platelet release reaction of platelet-derived growth factor and PF-4 in human platelets.
Slovenian: Cilostazol pri podganah in v celicah gladkih mišic človeka in vitro zavira tudi proliferacijo gladkih mišičnih celic in zavira reakcijo sproščanja trombocitov trombocitnega rastnega faktorja in PF-4 pri trombocitih pri ljudeh.
English: <Cilostazol-containing medicinal product> tablets should be taken 30 minutes before breakfast and the evening meal.
Slovenian: • <Zdravilo, ki vsebuje cilostazol>, tablete, morate vzeti 30 minut pred zajtrkom in večerjo.
English: Consequently, for patients concomitantly taking strong CYP3A4 or CYP2C19 inhibitors the recommended dose is 50 mg twice daily (see section
Slovenian: Posledično je za bolnike, ki sočasno jemljejo močne zaviralce CYP3A4 ali CYP2C19, priporočeni odmerek 50 mg dvakrat na dan (glejte poglavje 4.2).
English: Cilostazol has been shown to increase the AUC of lovastatin (sensitive substrate for CYP3A4) and its hydroxy acid by 70%.
Slovenian: Pokazalo se je, da cilostazol poveča AUC lovastatina (občutljivi substrat CYP3A4) in njegove hidroksi kisline za 70 %.
English: • beta blockers (e.g., labetalol, carvedilol);
Slovenian: • zaviralce beta (npr. labetalol, karvedilol)
English: Cilostazol is extensively metabolised by CYP enzymes, particularly CYP3A4 and CYP2C19 and to a lesser extent CYP1A2.
Slovenian: Cilostazol obsežno presnavljajo encimi CYP, zlasti CYP3A4 in CYP2C19, v manjši meri pa CYP1A2.
English: What <Cilostazol-containing medicinal product> looks like and contents of the pack The <Cilostazol-containing medicinal product> 50 mg tablet is a white, round, flat-faced tablet, debossed with “OG31” on one side.
Slovenian: Izgled <zdravila, ki vsebuje cilostazol>, in vsebina pakiranja <Zdravilo, ki vsebuje cilostazol,> 50 mg tablete, so bele, okrogle, ploske tablete z vtisom "OG31" na eni strani.
English: The Cmax and AUC of 4'-transhydroxy cilostazol were 173% and 209% greater in subjects with severe renal impairment.
Slovenian: Cmax in AUC 4'-trans-hidroksi cilostazola sta bila 173 % oz. 209 % višja pri osebah s hudo okvaro delovanja ledvic.
English: Based on these data, the recommended dose of cilostazol is 50 mg bid in the presence of ketoconazole and similar agents (e.g., itraconazole).
Slovenian: Na podlagi teh podatkov je priporočeni odmerek cilostazola 50 mg dvakrat na dan v prisotnosti ketokonazola in podobnih učinkovin (npr. itrokonazola).