FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients with rare hereditary problems of fructose intolerance or sucrase-isomaltase insufficiency should not take this medicinal product (see section 2).
Slovenian: Bolniki z redko dedno intoleranco za fruktozo ali s pomanjkanjem saharaze - izomaltaze ne smejo uporabljati tega zdravila (glejte poglavje 2).
English: Your doctor will decide how much Caspofungin Accord you need and for how long each day.
Slovenian: Zdravnik se bo odločil, koliko zdravila Kaspofungin Accord boste prejeli dnevno in trajanje zdravljenja.
English: Further metabolism involves peptide hydrolysis and N-acetylation.
Slovenian: V nadaljnji presnovi pride do peptidne hidrolize in N-acetilacije.
English: • Increased blood pressure and alterations in some laboratory blood tests (including kidney electrolyte and clotting tests), increased levels of the medicines you are taking that weaken the immune system
Slovenian: • zvišan krvni tlak in spremembe nekaterih laboratorijskih izvidov krvi (vključno z ledvičnimi elektroliti in s testi strjevanja krvi), zvišane koncentracije zdravil, ki jih uporabljate in oslabijo imunski sistem
English: In patients who were treated empirically or who had invasive candidiasis, a similar modest effect of age was seen in older patients relative to younger patients.
Slovenian: Pri bolnikih, ki so se zdravili empirično, ali so imeli invazivno kandidiazo je bil pri starejših bolnikih v primerjavi z mlajšimi bolniki opazen podoben zmeren vpliv starosti.
English: Increased caspofungin exposure was seen in adult patients with renal impairment and mild liver impairment, in female subjects, and in the elderly.
Slovenian: Večjo izpostavitev kaspofunginu so opazili pri odraslih bolnikih z ledvično okvaro in blago jetrno okvaro, pri ženskah in pri starejših.
English: Also reported in patients with invasive aspergillosis were pulmonary oedema, adult respiratory distress syndrome (ARDS), and radiographic infiltrates.
Slovenian: Pri bolnikih z invazivno aspergilozo so poročali tudi o pljučnem edemu, sindromu dihalne stiske pri odraslih (ARDS) in rentgensko vidnih infiltratih.
English: This finding may indicate that paediatric patients will have similar reductions with inducers as seen in adults.
Slovenian: To lahko kaže, da induktorji pri pediatričnih bolnikih povzročijo podobno zmanjšanje, kot je bilo ugotovljeno pri odraslih.
English: • Changes in some laboratory blood tests (including disease of blood clotting, platelets, red blood cells and white blood cells)
Slovenian: • spremembe nekaterih laboratorijskih izvidov krvi (vključno z motnjami strjevanja krvi, trombocitov, rdečih krvnih celic in belih krvnih celic)
English: ** If 70 mg vial is not available, the 70 mg dose can be prepared from two 50 mg vials
Slovenian: **Če 70 ml viala ni na voljo, lahko 70 ml odmerek pripravite iz dveh 50 ml vial.
English: • Loss of appetite, increase in amount of body fluid, imbalance of salt in the body, high sugar level in the blood, low calcium level in the blood, increase calcium level in the blood, low magnesium level in the blood, increase in acid level in the blood
Slovenian: • izguba apetita, povečanje količine telesne tekočine, porušeno ravnotežje soli v telesu, visoke vrednosti sladkorja v krvi, nizke vrednosti kalcija v krvi, zvišane vrednosti kalcija v krvi, nizke vrednosti magnezija v krvi, zvišanje vrednosti kisline v krvi
English: Tell your doctor, nurse or pharmacist if you are taking any of the following medicines:
Slovenian: Obvestite zdravnika, medicinsko sestro ali farmacevta, če jemljete katero od naslednjih zdravil:
English: To reconstitute the powder, bring the vial to room temperature and aseptically add 10.5 mL of water for injection.
Slovenian: Za pripravo koncentrata prenesite vialo na sobno temperaturo in vanjo aseptično dodajte 10,5 ml vode za injekcije.
English: Caspofungin acetate is a semi-synthetic lipopeptide (echinocandin) compound synthesised from a fermentation product of Glarea lozoyensis.
Slovenian: Kaspofunginijev acetat je polsintetična lipopeptidna (ehinokandin) spojina, sintetizirana iz fermentacijskega produkta Glarea-e lozoyensis.
English: • you are already taking cyclosporin (used to help prevent organ transplant rejection or to suppress your immune system) - as your doctor may need to run extra blood tests during your treatment.
Slovenian: • če že jemljete ciklosporin (ki se uporablja za preprečevanje reakcije zavrnitve presajenega organa ali za zaviranje vašega imunskega sistema) - zdravnik se bo med zdravljenjem morda odločil za dodatne preiskave krvi.
English: In two clinical studies performed in healthy adult subjects, cyclosporin A (one 4 mg/kg dose or two 3 mg/kg doses 12 hours apart) increased the AUC of caspofungin by approximately 35 %.
Slovenian: V dveh kliničnih študijah pri zdravih odraslih preiskovancih je ciklosporin A (en odmerek 4 mg/kg ali dva odmerka 3 mg/kg v 12-urnem razmiku) povečal AUC kaspofungina za približno 35 %.
English: The study excluded patients with suspected Candida endocarditis, meningitis, or osteomyelitis.
Slovenian: Iz študije so izključili bolnike s sumom na kandidiazni endokarditis, meningitis ali osteomielitis.
English: Stringent definitions, modelled after the Mycoses Study Group Criteria, were used for diagnosis of invasive aspergillosis and for response to therapy (favourable response required clinically significant improvement in radiographs as well as in signs and symptoms).
Slovenian: Za diagnozo invazivne aspergiloze in odziv na zdravljenje so uporabili stroge definicije, oblikovane po merilih Mycoses Study Group (za ugoden odziv je bilo potrebno klinično pomembno izboljšanje tako radiogramov kot tudi znakov in simptomov).
English: The second study was a prospective, open-label, non-comparative study estimating the safety and efficacy of caspofungin in paediatric patients (ages 6 months to 17 years) with invasive candidiasis, esophageal candidiasis, and invasive aspergillosis (as salvage therapy).
Slovenian: Druga študija je bila prospektivna, odprta, neprimerjalna študija varnosti in učinkovitosti kaspofungina pri pediatričnih bolnikih (starih od 6 mesecev do 17 let) z invazivno kandidiazo, ezofagealno kandidiazo in invazivno aspergilozo (kot rešilno zdravljenje).
English: CONTENTS BY WEIGHT, BY VOLUME OR BY UNIT OTHER
Slovenian: VSEBINA IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ENOT DRUGI PODATKI
English: PREPARATION OF THE SOLUTION FOR INFUSION IN ADULTS
Slovenian: PRIPRAVA RAZTOPINE ZA INFUNDIRANJE ZA ODRASLE
English: Caspofungin Accord may also cause Serious Cutaneous Adverse Reactions such as Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN).
Slovenian: Zdravilo Kaspofungin Accord lahko povzroči tudi resne kožne neželene učinke, kot npr. StevensJohnsonov sindrom (SJS) in toksično epidermalno nekrolizo (TEN).
English: There are no or limited data from the use of caspofungin in pregnant women.
Slovenian: Podatkov o uporabi kaspofungina pri nosečnicah ni oziroma so omejeni.
English: • Caspofungin Accord has not been studied in pregnant women.
Slovenian: • Uporabe zdravila Kaspofungin Accord pri nosečnicah niso preučevali.
English: Caspofungin is not a substrate for P-glycoprotein and is a poor substrate for cytochrome P450 enzymes.
Slovenian: Kaspofungin ni substrat za P-glikoprotein in je šibek substrat za encime sistema citokrom P450.
English: Only a trained healthcare professional who has read the complete directions should prepare the medicine (please see below “Instructions of how to reconstitute and dilute Caspofungin Accord”).
Slovenian: Zdravilo lahko pripravi le usposobljeni zdravstveni delavec, ki je prebral celotno navodilo (v nadaljevanju glejte "Navodilo za pripravo in razredčevanje zdravila Kaspofungin Accord").
English: If you have been given more Caspofungin Accord than you should
Slovenian: Če ste uporabili večji odmerek zdravila Kaspofungin Accord, kot bi smeli
English: However, in adult patients with invasive candidiasis, oesophageal candidiasis, or invasive aspergillosis who received multiple daily doses of caspofungin 50 mg, there was no significant effect of mild to advanced renal impairment on caspofungin concentrations.
Slovenian: Vendar pa pri odraslih bolnikih z invazivno kandidiazo, ezofagealno kandidiazo ali z invazivno aspergilozo, ki so dobivali kaspofungin 50 mg v večkratnih dnevnih odmerkih, blaga do napredovala ledvična okvara ni pomembno vplivala na koncentracijo kaspofungina.
English: The daily maintenance dose should not exceed 70 mg regardless of the patient's calculated dose.
Slovenian: Dnevni vzdrževalni odmerek ne sme preseči 70 mg, ne glede na izračunani odmerek za bolnika.
English: • The active substance is caspofungin.
Slovenian: • Zdravilna učinkovina je kaspofungin.
English: The incidence of resistance to caspofungin by various clinical isolates of Aspergillus is rare.
Slovenian: Pojavnost rezistence na kaspofungin pri različnih kliničnih izolatih vrste Candida in Aspergillus je redka.
English: Caspofungin acetate inhibits the synthesis of beta (1,3)-D-glucan, an essential component of the cell wall of many filamentous fungi and yeast.
Slovenian: Kaspofunginijev acetat zavira sintezo beta (1,3)-Dglukana, ki je bistvena sestavina celične stene številnih filamentoznih gliv in kvasovk.
English: What Caspofungin Accord is and what it is used for
Slovenian: Kaj je zdravilo Kaspofungin Accord in za kaj ga uporabljamo
English: For those patients who received more than 7 days of therapy with caspofungin, 50 % (26/52) had a favourable response.
Slovenian: Med bolniki, ki so se s kaspofunginom zdravili več kot 7 dni, se jih je na zdravljenje ugodno odzvalo 50 % (26/52).
English: This medicinal product contains sucrose.
Slovenian: To zdravilo vsebuje saharozo.
English: In adult patients with moderate liver impairment or in higher weight patients, a dosage adjustment may be necessary (see below).
Slovenian: Pri odraslih bolnikih z zmerno jetrno okvaro ali večjo telesno maso je lahko potrebna prilagoditev odmerka (glejte nadaljevanje).
English: In this group of patients, the safety of caspofungin at this higher dose appeared generally similar to patients receiving the 50-mg daily dose of caspofungin.
Slovenian: Kaže, da je v tej skupini bolnikov varnost kaspofungina pri višjem odmerku na splošno podobna kot pri bolnikih, ki so prejemali 50 mg odmerek kaspofungina na dan.
English: Invasive Aspergillosis in Adult Patients: Sixty-nine adult patients (age 18-80) with invasive aspergillosis were enrolled in an open-label, non-comparative study to evaluate the safety, tolerability, and efficacy of caspofungin.
Slovenian: Invazivna aspergiloza pri odraslih bolnikih: 69 odraslih bolnikov (starih 18-80 let) z invazivno aspergilozo je sodelovalo v odprti, neprimerjalni študiji za oceno varnosti, prenašanja in učinkovitosti kaspofungina.
English: Caution is advised when treating this age group.
Slovenian: Pri zdravljenju bolnikov iz te starostne skupine je potrebna previdnost.
English: • Changes in some laboratory blood tests.
Slovenian: • spremembe nekaterih laboratorijskih izvidov krvi
English: What you need to know before you are given Caspofungin Accord
Slovenian: Kaj morate vedeti, preden boste dobili zdravilo Kaspofungin Accord
English: SPECIAL WARNING THAT THE MEDICINAL PRODUCT MUST BE STORED OUT OF THE SIGHT AND REACH OF CHILDREN Keep out of the sight and reach of children.
Slovenian: POSEBNO OPOZORILO O SHRANJEVANJU ZDRAVILA ZUNAJ POGLEDA IN DOSEGA OTROK
English: Concomitant use of caspofungin with cyclosporin has been evaluated in healthy adult volunteers and in adult patients.
Slovenian: Sočasno zdravljenje s kaspofunginom in ciklosporinom so preučevali tako pri zdravih odraslih prostovoljcih kot pri odraslih bolnikih.
English: The proportion of patients with a serious drug-related adverse reaction or a drug-related adverse reaction leading to caspofungin discontinuation was comparable in the 2 treatment groups.
Slovenian: Delež bolnikov z zdravilom povezanimi resnimi neželenimi učinki ali z zdravilom povezanimi neželenimi učinki, zaradi katerih je bil kaspofungin ukinjen, je bil primerljiv v obeh skupinah.
English: Both 70 mg and 50 mg vials are available.
Slovenian: Na voljo so tako 70 mg kot 50 mg viale.
English: • Treatment of invasive aspergillosis in adult or paediatric patients who are refractory to or intolerant of amphotericin B, lipid formulations of amphotericin B and/or itraconazole.
Slovenian: • Zdravljenje invazivne aspergiloze pri odraslih ali pediatričnih bolnikih, ki so nedovzetni za zdravljenje z amfotericinom B, lipidnimi pripravki amfotericina B in/ali itrakonazolom ali teh zdravil ne prenašajo.
English: • difficulty breathing with wheezing or a rash that gets worse - you may be having an allergic reaction to the medicine.
Slovenian: • težave pri dihanju s piskanjem ali poslabšanje obstoječega izpuščaja - morda imate alergijsko reakcijo na zdravilo,
English: Caspofungin should be given as a single daily infusion.
Slovenian: Kaspofungin se daje v obliki infuzije enkrat na dan.
English: • Decreased blood albumin (a type of protein) in your blood, decreased potassium or low potassium levels in the blood
Slovenian: • zmanjšana vrednost albumina (vrsta beljakovine) v vaši krvi, zmanjšana vrednost kalija ali nizka vrednost kalija v krvi
English: Patients who develop abnormal liver function tests during caspofungin therapy should be monitored for evidence of worsening hepatic function and the risk/benefit of continuing caspofungin therapy should be re-evaluated.
Slovenian: Bolnike, pri katerih so se med zdravljenjem s kaspofunginom pojavili nenormalni izvidi jetrnih testov, je treba spremljati glede znakov poslabšanja delovanja jeter in pri njih ponovno oceniti razmerje med tveganjem in koristjo nadaljevanja zdravljenja s kaspofunginom.
English: Caspofungin should be initiated by a physician experienced in the management of invasive fungal infections.
Slovenian: Zdravljenje s kaspofunginom mora uvesti zdravnik z izkušnjami pri zdravljenju invazivnih glivnih okužb.
English: Repeated dose toxicity studies in rats and monkeys using doses up to 7-8 mg/kg given intravenously showed injection site reactions in rats and monkeys, signs of histamine release in rats, and evidence of adverse effects directed at the liver in monkeys.
Slovenian: Študije toksičnosti po ponavljajočih odmerkih pri podganah in opicah z odmerki do 7-8 mg/kg intravensko so pokazale reakcije na mestu vbrizganja pri podganah in opicah, znake sproščanja histamina pri podganah in znake neželenih učinkov na jetra pri opicah.
English: Candida species (Candida albicans [N = 1,032], Candida dubliniensis [N = 100], Candida glabrata [N = 151], Candida guilliermondii [N = 67], Candida kefyr [N = 62], Candida krusei [N = 147], Candida lipolytica [N = 20], Candida lusitaniae [N = 80], Candida parapsilosis [N = 215], Candida rugosa [N = 1], and Candida tropicalis [N = 258]), including isolates with multiple resistance transport mutations and those with acquired or intrinsic resistance to fluconazole, amphotericin B, and 5-flucytosine.
Slovenian: In vitro je kaspofungin učinkovit tudi proti Candida sp. (Candida albicans n = 1.032, Candida dubliniensis n = 100, Candida glabrata n = 151, Candida guilliermondii n = 67, Candida kefyr n = 62, Candida krusei n = 147, Candida lipolytica n = 20, Candida lusitaniae n = 80, Candida parapsilosis n = 215, Candida rugosa n = 1 in Candida tropicalis n = 258, vključno z izolati s prenosnimi mutacijami, ki so odgovorne za rezistenco na številne antibiotike, in tistimi s pridobljeno ali intrinzično rezistenco na flukonazol, amfotericin B in 5flucitozin.
English: Hypersensitivity reactions (anaphylaxis and possibly histamine-mediated adverse reactions) have been reported (see section 4.4).
Slovenian: Poročali so o preobčutljivostnih reakcijah (anafilaksiji in verjetno histaminsko posredovanih neželenih učinkih) (glejte poglavje 4.4).
English: Caspofungin did not increase the plasma levels of cyclosporin.
Slovenian: Kaspofungin ni povečal plazemskih koncentracij ciklosporina.
English: In this study, the caspofungin dose was administered over 2 hours (instead of the routine 1-hour administration).
Slovenian: V tej študiji so bolnikom dajali odmerek kaspofungina dve uri (namesto običajnega enournega dajanja).
English: There is limited treatment experience in patients 65 years of age and older (see section 5.2).
Slovenian: Izkušenj z zdravljenjem bolnikov, starih 65 let ali več, je malo (glejte poglavje 5.2).
English: The most common drug-related clinical adverse experiences reported in paediatric patients treated with caspofungin were pyrexia (11.7%), rash (4.7%) and headache (2.9%).
Slovenian: Najpogostejši klinični neželeni učinki, povezani z zdravilom, o katerih so poročali pri pediatričnih bolnikih, zdravljenih s kaspofunginom, so bili zvišana telesna temperatura (11,7 %), izpuščaj (4,7 %) in glavobol (2,9 %).
English: The caspofungin plasma concentrations in these adolescents were reduced relative to adults receiving 70 mg daily, the dose most often administered to adolescents.
Slovenian: Koncentracija kaspofungina v plazmi je bila pri teh mladostnikih nižja kot pri odraslih, ki so dobivali 70 mg na dan, tj. odmerek, ki so ga najpogosteje dobili mladostniki.
English: Patients in the non-comparative Aspergillus study often had serious predisposing medical conditions (e.g., bone marrow or peripheral stem cell transplants, haematologic malignancy, solid tumours or organ transplants) requiring multiple concomitant medications.
Slovenian: Bolniki v neprimerjalni študiji Aspergillusa so pogosto imeli resna predisponirajoča zdravstvena stanja (npr. presaditev kostnega mozga ali perifernih matičnih celic, hematološke malignome, solidne tumorje ali presajene organe), zaradi katerih so morali sočasno dobivati več zdravil.
English: Blood and lymphatic system disorders eosinophil count increased
Slovenian: Bolezni krvi in limfatičnega sistema povečano število eozinofilcev
English: Isolates of Candida with reduced susceptibility to caspofungin have been identified in a small number of patients during treatment (MICs for caspofungin >2 mg/L (4- to 30-fold MIC increases) have been reported using standardized MIC testing techniques approved by the CLSI).
Slovenian: Pri manjšem številu bolnikov so med zdravljenjem odkrili izolate vrste Candida z zmanjšano občutljivostjo na kaspofungin (poročali so o MIC za kaspofungin > 2 mg/l (4-do 30-kratno povečanje MIC), pri čemer so uporabili standardizirane tehnike za testiranje MIC, odobrene s strani CLSI).
English: Caspofungin has also been evaluated at 150 mg daily (for up to 51 days) in 100 adult patients (see section 5.1).
Slovenian: Ovrednotili so tudi odmerke po 150 mg kaspofungina na dan (v času do 51 dni) pri 100 odraslih bolnikih (glejte poglavje 5.1).
English: For adult patients with mild hepaticimpairment (Child-Pugh score 5 to 6), no dosage adjustment is needed.
Slovenian: Pri odraslih bolnikih z blago jetrno okvaro (stopnja Child-Pugh 5 do 6 točk) prilagoditev odmerka ni potrebna.
English: The following adverse reactions were reportedduring clinical studies and/or post-marketing use:
Slovenian: Seznam neželenih učinkov v preglednici V kliničnih študijah in/ali v obdobju trženja so poročali o naslednjih neželenih učinkih:
English: This infection is caused by fungal (yeast) cells called Candida.
Slovenian: Te okužbe povzročajo glive (kvasovke), imenovane Candida.
English: After two weeks' administration rifampicin had limited effect on AUC, but trough levels were 30 % lower than in adult subjects who received caspofungin alone.
Slovenian: Po dveh tednih zdravljenja je imel rifampicin omejen učinek na AUC, koncentracije, izmerjene tik pred naslednjim odmerkom, pa so bile 30 % manjše kot pri odraslih preiskovancih, ki so dobivali samo kaspofungin.
English: In the studies involving patients with documented Candida infections, the majority of the patients with invasive Candida infections had serious underlying medical conditions (e.g., haematologic or other malignancy, recent major surgery, HIV) requiring multiple concomitant medications.
Slovenian: V študijah pri bolnikih s potrjenimi okužbami s Candido je imela večina bolnikov z invazivnimi okužbami s Candido resne osnovne bolezni (npr. hematološki ali kakšen drug malignom, nedavni večji kirurški poseg, HIV), zaradi katerih so morali sočasno dobivati več zdravil.
English: Nervous system disorders headache
Slovenian: Bolezni živčevja glavobol
English: For reconstitution directions see section 6.6.
Slovenian: Za navodila glede rekonstitucije glejte poglavje 6.6.
English: The safety and efficacy of caspofungin have not been sufficiently studied in clinical trials involving neonates and infants below 12 months of age.
Slovenian: Varnost in učinkovitost kaspofungina nista bili dovolj raziskani v kliničnih preskušanjih, ki bi vključevala novorojenčke in dojenčke, mlajše od 12 mesecev.
English: Renal impairment: In a clinical study of single 70 mg doses, caspofungin pharmacokinetics were similar in adult volunteers with mild renal impairment (creatinine clearance 50 to 80 mL/min) and control subjects.
Slovenian: Okvara ledvic: V klinični študiji enkratnih 70 mg odmerkov je bila farmakokinetika kaspofungina pri odraslih prostovoljcih z blago ledvično okvaro (kreatininski očistek 50 do 80 ml/min) podobna kot pri kontrolnih preiskovancih.
English: However, variability was seen in both C1 hr (Day 4 geometric mean 11.73 µg/mL, range 2.63 to 22.05 µg/mL) and C24 hr (Day 4 geometric mean 3.55 µg/mL, range 0.13 to 7.17 µg/mL).
Slovenian: Vendar pa je bila variabilnost opazna tako pri C1 h (geometrična sredina 4. dan 11,73 µg/ml, razpon od 2,63 do 22,05 µg/ml) kot pri C24 h (geometrična sredina 4. dan 3,55 µg/ml, razpon od 0,13 do 7,17 µg/ml).
English: In the empirical therapy study patients had received chemotherapy for malignancy or had undergone hematopoietic stem-cell transplantation (including 39 allogeneic transplantations).
Slovenian: Bolniki v študiji empiričnega zdravljenja so dobivali kemoterapijo zaradi malignoma ali so prestali presaditev hematopoetskih matičnih celic (vključno z 39 alogenskimi presaditvami).
English: Patients had to be either refractory to (disease progression or failure to improve with other antifungal therapies given for at least 7 days) (84 % of the enrolled patients) or intolerant of (16 % of enrolled patients) other standard antifungal therapies.
Slovenian: Bolniki so morali biti nedovzetni za druga standardna protiglivna zdravila (napredovanje bolezni ali nespremenjeno stanje ob vsaj 7 dnevnem prejemanju drugih protiglivnih zdravil) (84 % vključenih bolnikov) ali jih niso smeli prenašati (16 % vključenih bolnikov).
English: • Loss of kidney function, sudden loss of kidney function
Slovenian: • prenehanje delovanja ledvic, nenadno prenehanje delovanja ledvic
English: Among patients with extrapulmonary disease, 2 of 8 patients who also had definite, probable, or possible CNS involvement had a favourable response.
Slovenian: Med bolniki z zunaj-pljučno boleznijo sta se na zdravljenje ugodno odzvala 2 bolnika od 8 z gotovo, verjetno ali možno okužbo osrednjega živčevja.
English: BSA (m2) X 50 mg/m2 = Daily Maintenance Dose
Slovenian: Telesna površina (m2) X 50 mg/m2 = dnevni vzdrževalni odmerek
English: Equilibrate the refrigerated vial of Caspofungin Accord to room temperature.
Slovenian: Pustite, da se ohlajena viala z zdravilom Kaspofungin Accord ogreje na sobno temperaturo.
English: Supplied in packs of 1 vial.
Slovenian: Zdravilo je na voljo v pakiranjih po 1 vialo.
English: Talk to your doctor, nurse or pharmacist before you are given Caspofungin Accord if:
Slovenian: Posvetujte se z zdravnikom, medicinsko sestro ali farmacevtom, preden dobite zdravilo Kaspofungin Accord:
English: Studies in vitro and in vivo demonstrate that exposure of Aspergillus to caspofungin results in lysis and death of hyphal apical tips and branch points where cell growth and division occur.
Slovenian: Študije in vitro in in vivo so pokazale, da pri izpostavitvi glive Aspergillus kaspofunginu pride do lize in odmrtja apikalnih vršičkov in mest vejanja hif, kjer se odvijata celična rast in delitev.