FrancophonIA/ELRC3.0 huggingface dataset:
English: 24-Hour Mean SBP: LS Mean Change from Baseline (BL) to Week 6 (mm Hg) Study 1
Danish: 24-timers middel SBP: LS middel ændring fra baseline (BL) til uge 6 (mm Hg) Studie 1
English: Fumaric acid (E 297) Sodium hydroxide Hydroxypropylcellulose (E 463) Croscarmellose sodium Cellulose, microcrystalline (E 460) Magnesium stearate (E 572)
Danish: Hydroxypropylcellulose (E 463) Croscarmellosenatrium Cellulose, mikrokrystallinsk (E 460) Magnesiumstearat (E 572)
English: Blood creatine phosphokinase increased Blood creatinine increased Blood uric acid increased / Hyperuricemia
Danish: Forhøjet blodkreatinin Forhøjet urinsyre i blodet/hyperurikæmi
English: These are ranked by frequency, using the following convention: very common (≥ 1/10); common (≥ 1/100, < 1/10); uncommon (≥ 1/1,000, < 1/100); rare (≥ 1/10,000, < 1/1,000); very rare (< 1/10,000), including isolated reports.
Danish: Bivirkningerne er opdelt efter frekvens ud fra følgende konvention: Meget almindelig (≥ 1/10), almindelig (≥ 1/100 til < 1/10), ikke almindelig (≥ 1/1.000 til < 1/100), sjælden (≥ 1/10.000 til
English: Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium.
Danish: Angiotensin II er det primære pressorstof af reninangiotensinsystemet med virkninger, der omfatter vasokonstriktion, stimulering af syntese og frigivelse af aldosteron, hjertestimulering og renal reabsorption af natrium.
English: Swelling of the hands, ankles or feet is more common (in less than 1 in 10 users) when Ipreziv is taken with amlodipine (a calcium channel blocker for treating hypertension) than when Ipreziv is taken alone (less than 1 in 100 users).
Danish: Hævelser i hænder, ankler og fødder er mere almindelige (forekommer hos færre end 1 ud af 10 brugere), når Ipreziv tages sammen med amlodipin (en kalciumkanalblokker til behandling af forhøjet blodtryk), end når Ipreziv tages alene (forekommer hos færre end 1 ud af 100 brugere).
English: What Ipreziv contains - The active substance is azilsartan medoxomil (as potassium) either 20 mg, 40 mg or 80 mg - The other ingredients are mannitol, fumaric acid, sodium hydroxide, hydroxypropylcellulose,
Danish: Ipreziv indeholder: - Aktivt stof: azilsartan medoxomil (som kalium) enten 20 mg, 40 mg eller 80 mg - Øvrige indholdsstoffer: mannitol, fumarsyre, natriumhydroxid, hydroxypropylcellulose,
English: As with all other angiotensin II receptor antagonist medicines, azilsartan medoxomil may be less effective in lowering the blood pressure in black patients.
Danish: Ligesom andre angiotensin II-receptorantagonister, kan azilsartan medoxomil være mindre effektivt til at sænke blodtrykket hos negroide patienter.
English: Mechanism of action and pharmacodynamic effect Azilsartan medoxomil is an orally active prodrug that is rapidly converted to the active moiety, azilsartan, which selectively antagonises the effects of angiotensin II by blocking its binding to the AT1 receptor in multiple tissues (see section 5.2).
Danish: Virkningsmekanisme og farmakodynamisk virkning Azilsartan medoxomil er et oralt aktivt prodrug, der hurtigt omdannes til den aktive del, azilsartan, som selektivt antagoniserer virkningerne af angiotensin II ved at blokere bindingen heraf til AT1receptoren i mange vævstyper (se pkt.
English: Hypotension in volume- and /or salt-depleted patients In patients with marked volume- and/or salt-depletion (e.g. patients with vomiting, diarrhoea or taking high doses of diuretics) symptomatic hypotension could occur after initiation of treatment with Ipreziv.
Danish: Hypotension hos volumen- og/eller saltdepleterede patienter Hos patienter med markant volumen- og saltdepletering (f.eks. patienter med opkastninger, diarré, eller patienter, som har taget høje doser diuretika), kan der forekomme symptomatisk hypotension efter initiering af behandling med Ipreziv.
English: When Ipreziv was coadministered with amlodipine, the frequency of peripheral oedema was increased from uncommon to common, but was lower than amlodipine alone.
Danish: Når Ipreziv blev administreret samtidig med amlodipin, blev frekvensen af perifere ødemer forhøjet fra ikke almindelig til almindelig, men frekvensen var lavere end for amlodipin alene.
English: The incidence of elevations in serum creatinine following treatment with Ipreziv was similar to placebo in the randomised placebo-controlled monotherapy studies.
Danish: Incidensen af forhøjet serumkreatinin efter behandling med Ipreziv svarede til placebo i de randomiserede, placebokontrollerede monoterapistudier.
English: Nonclinical studies demonstrated that azilsartan did not appear to affect male or female fertility in the rat (see section 5.3).
Danish: Non-kliniske studier viser, at azilsartan ikke synes at påvirke fertiliteten hos han- eller hunrotter (se pkt.
English: Detailed information on this product is available on the website of the European Medicines Agency http://www.ema.europa.eu
Danish: DATO FOR ÆNDRING AF TEKSTEN Yderligere information om Ipreziv findes på Det Europæiske Lægemiddelagenturs hjemmeside http://www.ema.europa.eu.
English: Ipreziv has not been studied in patients with severe hepatic impairment.
Danish: Ipreziv er ikke undersøgt hos patienter med svært nedsat leverfunktion.
English: The blood pressure lowering effect of Ipreziv was also maintained throughout the 24-hour dosing interval.
Danish: Iprezivs blodtryksreducerende virkning blev også opretholdt over hele doseringsintervallet på 24 timer.
English: As with other angiotensin II receptor antagonists and angiotensin converting enzyme inhibitors the antihypertensive effect was lower in black patients (usually a lowrenin population).
Danish: Som det også er tilfældet for andre angiotensin IIreceptorantagonister og angiotensin-konverterende enzyminhibitorer, var den antihypertensive virkning lavere hos negroide patienter (normalt en population med lav-renin tilstande).
English: SPECIAL STORAGE CONDITIONS Store in the original package in order to protect from light and moisture.
Danish: SÆRLIGE OPBEVARINGSBETINGELSER Opbevares i den originale pakning for at beskytte mod lys og fugt.
English: In active-comparator studies with either valsartan or ramipril, the blood-pressure-lowering effect with Ipreziv was sustained during long-term treatment.
Danish: I studier med aktive komparatorer med enten valsartan eller ramipril blev Iprezivs antihypertensive virkning opretholdt ved langtidsbehandling.
English: For Ipreziv, olmesartan medoxomil and valsartan, respectively dizziness was observed at an incidence of 3.0%, 3.3% and 1.8%; headache at 4.8%, 5.5% and 7.6% and dyslipidemia at 3.5%, 2.4% and 1.1%.
Danish: Svimmelhed blev observeret med en hyppighed på 3,0 %, 3,3 % og 1,8 %, hovedpine med en hyppighed på 4,8 %, 5,5 % og 7,6 % og dyslipædimi med en hyppighed på 3,5 %, 2,4 % og 1,1 % for henholdsvis Ipreziv, olmesartan medoxomil og valsartan.
English: Food does not affect the bioavailability of azilsartan (see section 4.2).
Danish: Føde påvirker ikke azilsartans biotilgængelighed (se pkt.
English: Common side effects affecting less than 1 in 10 people: - Dizziness - Diarrhoea - Increased blood creatine phosphokinase (an indicator of muscle damage).
Danish: Almindelige bivirkninger (forekommer hos færre end 1 ud af 10 personer): - Svimmelhed - Diarré - Forhøjet blodkreatinfosfokinase (viser muskelskade).
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION 7 December 2011
Danish: DATO FOR FØRSTE MARKEDSFØRINGSTILLADELSE/FORNYELSE AF TILLADELSEN
English: When Ipreziv was coadministered with chlortalidone, the frequencies of blood creatinine increased and hypotension were increased from uncommon to common.
Danish: Når Ipreziv blev administreret samtidig med chlortalidon, forhøjedes frekvensen af blodkreatinin, og frekvensen af hypotension blev forhøjet fra ikke almindelig til almindelig.
English: As there is limited experience of use of Ipreziv in patients with mild to moderate hepatic impairment close monitoring is recommended and consideration should be given to 20 mg as a starting dose (see section 5.2).
Danish: Da der er begrænset erfaring med brug af Ipreziv til patienter med mild eller moderat nedsat leverfunktion, anbefales tæt monitorering, og det bør overvejes at give 20 mg som startdosis (se pkt.
English: In patients whose vascular tone and renal function depend predominantly on the activity of the reninangiotensin-aldosterone system (e.g. patients with congestive heart failure, severe renal impairment or renal artery stenosis), treatment with medicinal products that affect this system, such as angiotensinconverting enzyme inhibitors and angiotensin II receptor antagonists, has been associated with acute hypotension, azotaemia, oliguria or, rarely, acute renal failure.
Danish: Hos patienter, hvis vaskulære tonus og nyrefunktion overvejende afhænger af aktiviteten af reninangiotensin-aldosteronsystemet (f.eks. patienter med kongestivt hjertesvigt, svært nedsat nyrefunktion eller nyrearteriestenose), har behandling med lægemidler, som påvirker dette system, såsom angiotensin-konverterende enzyminhibitorer og angiotensin II-receptorantagonister, været forbundet med akut hypotension, azotæmi, oliguri eller i sjældne tilfælde med akut nyresvigt.
English: Rash, pruritus Angioedema
Danish: Udslæt, pruritus Angioødem
English: - have severe liver disease - have heart problems (including heart failure, recent heart attack) - have ever had a stroke - have low blood pressure or feel dizzy or lightheaded - are vomiting, have recently had severe vomiting, or have diarrhoea - have elevated levels of potassium in your blood - have a disease of the adrenal gland called primary hyperaldosteronism - have been told that you have a narrowing of the valves in your heart (called “aortic or mitral valve stenosis”) or that the thickness of your heart muscle is abnormally increased (called
Danish: - har hjerteproblemer (herunder dårligt hjerte, nyligt hjerteanfald) - har eller tidligere har haft et slagtilfælde - har lavt blodtryk eller føler dig svimmel eller uklar - kaster op, har haft svære opkastninger for nylig eller har diarré - har forhøjet kaliumindhold i blodet - har en sygdom i binyren, som kaldes primær hyperaldosteronisme - har fået at vide, at du har en indsnævring i dine hjerteklapper (såkaldt “aorta- eller mitralklapstenose”), eller at tykkelsen på din hjertemuskel er unormalt forøget (såkaldt
English: The antihypertensive effect of Ipreziv occurred within the first 2 weeks of dosing with the full effect achieved by 4 weeks.
Danish: Iprezivs antihypertensive virkning viste sig inden for de 2 første uger efter dosering, med fuld opnået virkning efter 4 uger.
English: Your doctor may need to change your dose and/or to take other precautions if you are taking an ACE-inhibitor or aliskiren (see also information under the headings “Do not take Ipreziv” and “Warnings and precautions”).
Danish: Hvis du samtidig tager en ACE-hæmmer eller aliskiren (se også information under overskrifterne ”Tag ikke Ipreziv” og ”Advarsler og forsigtighedsregler”).
English: Coadministration of Ipreziv with diuretics, such as chlortalidone, resulted in a greater incidence of creatinine elevations, an observation consistent with that of other angiotensin II receptor antagonists and angiotensin converting enzyme inhibitors.
Danish: Samtidig administration af Ipreziv med diuretika, såsom chlortalidon, resulterede i en større forekomst af kreatininforhøjelser, hvilket er en observation, der stemmer overens med observationen for andre angiotensin II-receptorantagonister og angiotensin-konverterende enzyminhibitorer.
English: Doses were force-titrated at Week 2 from 20 to 40 mg and 40 to 80 mg for Ipreziv, and 20 to 40 mg and 160 to 320 mg, respectively, for olmesartan medoxomil and valsartan
Danish: 80 mg for Ipreziv, og 20 til 40 mg og 160 til 320 mg for henholdsvis olmesartan medoxomil og valsartan
English: - The concomitant use of Ipreziv with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73m2) (see sections 4.5 and 5.1).
Danish: - Samtidig brug af Ipreziv og lægemidler indeholdende aliskiren er kontraindiceret hos patienter med diabetes mellitus eller nedsat nyrefunktion (GFR < 60 ml/min/1,73m2) (se pkt 4.5 og 5.1).
English: Uncommon side effects affecting less than 1 in 100 people: - Low blood pressure, which may make you feel faint or dizzy - Feeling tired - Swelling of the hands, ankles or feet (peripheral oedema) - Skin rash and itching - Nausea - Muscle spasms - Increased serum creatinine in the blood (an indicator of kidney function) - Increased uric acid in the blood (an indicator of kidney function).
Danish: Ikke almindelige bivirkninger (forekommer hos færre end 1 ud af 100 personer): - Lavt blodtryk, der kan bevirke, at du føler dig svag eller svimmel - Træthedsfølelse - Hævede hænder, ankler eller fødder (perifert ødem) - Hududslæt og kløe - Kvalme - Muskelspasmer - Forhøjet indhold af serumkreatinin i blodet (viser hvordan nyrerne fungerer) - Forhøjet indhold af urinsyre i blodet (tegn på hvordan nyrerne fungerer).
English: Other medicines and Ipreziv
Danish: Brug af anden medicin sammen med Ipreziv
English: Hypovolemia should be corrected prior to administration of Ipreziv, or the treatment should start under close medical supervision, and consideration can be given to a starting dose of 20 mg.
Danish: Hypovolæmi bør korrigeres før behandling med Ipreziv, eller behandlingen bør starte under tæt lægelig overvågning.
English: Ipreziv is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.
Danish: Din læge vil sædvanligvis anbefale en anden behandling til dig, hvis du ønsker at amme dit barn, især hvis dit barn er nyfødt eller født for tidligt.
English: If blood pressure is not adequately controlled with Ipreziv alone, additional blood pressure reduction can be achieved when Ipreziv is coadministered with other antihypertensive medicinal products, including diuretics (such as chlortalidone and hydrochlorothiazide) and calcium channel blockers (see sections 4.3, 4.4, 4.5 and 5.1).
Danish: Hvis blodtrykket ikke er tilstrækkeligt kontrolleret med Ipreziv alene, kan der opnås yderligere blodtryksreduktion, når Ipreziv administreres i kombination med andre antihypertensiva, herunder diuretika (såsom chlortalidon og hydrochlorthiazid) og calciumkanalblokkere (se pkt.
English: In the repeated-dose toxicity studies, doses producing exposure comparable to that in the clinical therapeutic range caused reduced red cell parameters, changes in the kidney and renal haemodynamics, as well as increased serum potassium in normotensive animals.
Danish: I toksicitetsstudier med gentagne doser i normotensive dyr, frembringer eksponering, som kan sammenlignes med eksponeringen i det kliniske, terapeutiske interval, reduktion af de røde blodlegemer, ændringer i nyre- og leverhæmodynamik, såvel som forhøjet serumkalium.
English: Aortic and mitral valve stenosis, obstructive hypertrophic cardiomyopathy Special caution is indicated in patients suffering from aortic or mitral valve stenosis, or hypertrophic obstructive cardiomyopathy (HOCM).
Danish: Aorta- og mitralklapstenose, obstruktiv hypertrofisk kardiomyopati Der skal udvises ekstra forsigtighed hos patienter med aorta- eller mitralklapstenose eller hypertrofisk obstruktiv kardiomyopati.
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu
Danish: Denne indlægsseddel blev senest godkendt den {MM/YYYY} Du kan finde yderligere information om Ipreziv på Det Europæiske Lægemiddelagenturs hjemmeside: http://www.ema.europa.eu.
English: Based on experience with the use of other medicinal products that affect the renin-angiotensinaldosterone system, concomitant use of Ipreziv with potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, or other medicinal products that may increase potassium levels (e.g. heparin) may lead to increases in serum potassium in hypertensive patients (see section 4.5).
Danish: Baseret på erfaringen med brug af andre lægemidler, der påvirker renin-angiotensinaldosteronsystemet, kan samtidig anvendelse af Ipreziv med kaliumbesparende diuretika, kaliumtilskud, salterstatninger indeholdende kalium eller andre lægemidler, der kan øge kaliumniveauet (f.eks. heparin) medføre stigninger i serumkalium hos hypertensive patienter (se pkt.
English: telmisartan, irbesartan).
Danish: (hæmoglobin).
English: Takeda Pharma A/S, Dybendal Alle 10, 2630 Taastrup, Denmark Manufacturer:
Danish: Indehaver af markedsføringstilladelsen: Takeda Pharma A/S, Dybendal Alle 10, 2630 Taastrup, Danmark
English: Following oral administration, azilsartan medoxomil is rapidly hydrolyzed to the active moiety azilsartan in the gastrointestinal tract and/or during absorption.
Danish: Efter oral administration hydrolyseres azilsartan medoxomil hurtigt til den aktive del azilsartan i mave-tarm-kanalen og/eller under absorption.
English: IPREZIV 20 MG TABLETS IPREZIV 40 MG TABLETS IPREZIV 80 MG TABLETS
Danish: IPREZIV 20 MG TABLETTER IPREZIV 40 MG TABLETTER IPREZIV 80 MG TABLETTER
English: No initial dose adjustment with Ipreziv is necessary in elderly patients (see section 5.2), although consideration can be given to 20 mg as a starting dose in the very elderly (≥ 75 years), who may be at risk of hypotension.
Danish: 5.2), selvom det kan overvejes at give 20 mg som startdosis til de noget ældre patienter (≥ 75 år), der kan have risiko for hypotension.
English: MINIMUM PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING Blister pack
Danish: MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS Blisterpakning
English: Dual blockade of the renin-angiotensin-aldosterone system (RAAS) There is evidence that the concomitant use of ACE inhibitors, angiotensin II receptor blockers or aliskiren increases the risk of hypotension, hyperkalaemia and decreased renal function (including acute renal failure).
Danish: Dobbelt hæmning af renin-angiotensin-aldosteron-systemet (RAAS) Der er tegn på, at samtidig brug af ACE-hæmmere og angiotensin II-receptorantagonister eller aliskiren øger risikoen for hypotension, hyperkaliæmi og nedsat nyrefunktion (inklusive akut nyresvigt).
English: Ipreziv is not recommended in early pregnancy, and must NOT be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Danish: Ipreziv bør ikke anvendes tidligt i graviditeten, og Ipreziv må IKKE anvendes, hvis du er længere end 3 måneder henne i graviditeten.
English: BATCH NUMBER Lot
Danish: FREMSTILLERENS BATCHNUMMER Batch
English: As with other angiotensin II receptor antagonists the combination of lithium and Ipreziv is not recommended (see section 4.5).
Danish: Som for andre angiotensin II-receptorantagonister frarådes kombinationen af lithium og Ipreziv (se pkt.
English: Ipreziv has not been studied in patients with severe hepatic impairment and therefore its use is not recommended in this patient group (see sections 4.4 and 5.2).
Danish: Ipreziv er ikke blevet undersøgt hos patienter med svært nedsat leverfunktion, og derfor bør Ipreziv ikke anvendes hos denne patientgruppe (se pkt.
English: Adverse reactions were reported at a similar frequency for the Ipreziv 20 mg dose as with the 40 and 80 mg doses in one placebo controlled study.
Danish: I et placebokontrolleret studie blev der indberettet samme hyppighed af bivirkninger ved Ipreziv 20 mg dosis, som ved doser på 40 mg og 80 mg.
English: Dose dependent adverse events including dizziness, hypotension and serum creatinine elevations were more frequent with diuretic coadministration compared with Ipreziv alone, while hypokalemia was less frequent compared with diuretic alone.
Danish: Dosisafhængige bivirkninger, herunder svimmelhed, hypotension og forhøjet serumkreatininniveau, forekom hyppigere med samtidig administration af et diuretikum sammenlignet med Ipreziv alene.
English: The elevations in serum creatinine during coadminstiration of Ipreziv with diuretics were associated with larger blood pressure reductions compared with a single medicinal product.
Danish: Stigningerne i serum-kreatinin var forbundet med en større blodtryksreduktion ved samtidig administration af Ipreziv og diuretika sammenlignet med administration af et enkelt lægemiddel alene.
English: INFORMATION IN BRAILLE Ipreziv 40 mg
Danish: INFORMATION I BRAILLE-SKRIFT Ipreziv 40 mg
English: EU/1/11/735/001 14 tablets EU/1/11/735/002 28 tablets EU/1/11/735/012 30 tablets EU/1/11/735/003 56 tablets EU/1/11/735/013 90 tablets EU/1/11/735/004 98 tablets
Danish: EU/1/11/735/001 14 tabletter EU/1/11/735/002 28 tabletter EU/1/11/735/012 30 tabletter EU/1/11/735/003 56 tabletter EU/1/11/735/013 90 tabletter EU/1/11/735/004 98 tabletter
English: EU/1/11/735/016 14 tablets EU/1/11/735/009 28 tablets EU/1/11/735/017 30 tablets EU/1/11/735/010 56 tablets EU/1/11/735/018 90 tablets EU/1/11/735/011 98 tablets
Danish: EU/1/11/735/016 14 tabletter EU/1/11/735/009 28 tabletter EU/1/11/735/017 30 tabletter EU/1/11/735/010 56 tabletter EU/1/11/735/018 90 tabletter EU/1/11/735/011 98 tabletter
English: Epidemiological evidence regarding the risk of teratogenicity following exposure to angiotensin converting enzyme inhibitors during the first trimester of pregnancy has not been conclusive; however, a small increase in risk cannot be excluded.
Danish: Ud fra de epidemiologiske data, kan man ikke konkludere, at behandling med angiotensinkonverterende enzyminhibitorer i 1. trimester medfører en risiko for teratogenicitet.
English: EU/1/11/735/005 14 tablets EU/1/11/735/006 28 tablets EU/1/11/735/014 30 tablets EU/1/11/735/007 56 tablets EU/1/11/735/015 90 tablets EU/1/11/735/008 98 tablets
Danish: EU/1/11/735/005 14 tabletter EU/1/11/735/006 28 tabletter EU/1/11/735/014 30 tabletter EU/1/11/735/007 56 tabletter EU/1/11/735/015 90 tabletter EU/1/11/735/008 98 tabletter
English: Your doctor may increase this dose to a maximum of 80 mg once a day depending on blood pressure response.
Danish: Afhængigt af Iprezivs påvirkning af dit blodtryk, kan din læge vælge at øge denne dosis til højst 80 mg én gang dagligt.
English: Musculoskeletal and connective tissue disorders General disorders and administration site conditions
Danish: Almene symptomer og reaktioner på administrationsstedet
English: INFORMATION IN BRAILLE Ipreziv 80 mg
Danish: INFORMATION I BRAILLE-SKRIFT Ipreziv 80 mg
English: White to nearly white round tablets, 7.6 mm in diameter, debossed “ASL” on one side and “40” on the other.
Danish: Hvide til næsten hvide, runde tabletter, 7,6 mm i diameter, præget med ”ASL” på den ene side og ”40” på den anden side.
English: Caution should be exercised in hypertensive patients with congestive heart failure as there is no experience of use of Ipreziv in these patients (see section 4.4).
Danish: Der bør udvises forsigtighed hos hypertensive patienter med kongestivt hjertesvigt, da der ikke er erfaring med brug af Ipreziv til disse patienter (se pkt.
English: What Ipreziv looks like and contents of the pack Ipreziv are white round tablets debossed “ASL” on one side and either “20”, “40” or “80” on the other.
Danish: Ipreziv er hvide, runde tabletter mærket med ”ASL” på den ene side og enten ”20”, ”40” eller ”80” på den anden side.
English: Two large randomised, controlled trials (ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial) and VA NEPHRON-D (The Veterans Affairs Nephropathy in Diabetes)) have examined the use of the combination of an ACE inhibitor with an angiotensin II receptor blocker.
Danish: Kombinationen af en ACE-hæmmer og en angiotensin II-receptorantagonist er undersøgt i to store randomiserede, kontrollerede studier (ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial) og VA NEPHRON-D (The Veterans Affairs Nephropathy in Diabetes)).
English: INFORMATION IN BRAILLE Ipreziv 20 mg
Danish: INFORMATION I BRAILLE-SKRIFT Ipreziv 20 mg