FrancophonIA/ELRC3.0 huggingface dataset:
English: • Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached.
Croatian: • Uoči svake izmjene sustava za upravljanje rizicima, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist /rizik, odnosno kada je omjer korist/rizik rezultat ostvarenja nekog važnog cilja (u smislu farmakovigilancije ili smanjenja rizika).
English: This is most likely to happen within 4 hours after taking VIAGRA.
Croatian: To će se najvjerojatnije dogoditi unutar 4 sata nakon uzimanja lijeka VIAGRA.
English: What VIAGRA is and what it is used for
Croatian: Što je VIAGRA i za što se koristi
English: Orodispersible tablets can be taken with or without water.
Croatian: Raspadljive tablete za usta mogu se uzimati sa ili bez vode.
English: Tell your doctor or pharmacist if you are already taking riociguat.
Croatian: Obavijestite svog liječnika ili ljekarnika ako već uzimate riocigvat.
English: If you feel that the effect of VIAGRA is too strong or too weak, talk to your doctor or pharmacist.
Croatian: Ako osjećate da je učinak lijeka VIAGRA prejak ili preslab, obratite se svom liječniku ili ljekarniku.
English: It should be taken immediately upon removal from the blister.
Croatian: Potrebno ju je uzeti odmah nakon otvaranja blistera.
English: In order for VIAGRA to be effective, sexual stimulation is required.
Croatian: Kako bi VIAGRA djelovala, neophodna je seksualna stimulacija.
English: VIAGRA will only help you to get an erection if you are sexually stimulated.
Croatian: VIAGRA će Vam pomoći u postizanju erekcije jedino ako ste seksualno stimulirani.
English: Recommend tablet be taken on an empty stomach.
Croatian: Preporučuje se uzimanje tablete na prazan želudac.
English: To get the maximum benefit from your medicine, you are advised not to drink excessive amounts of alcohol before taking VIAGRA.
Croatian: Kako biste izvukli najviše koristi od lijeka, savjetuje se da ne uzimate veće količine alkohola prije uzimanja lijeka VIAGRA.
English: VIAGRA may have a minor influence on the ability to drive and use machines.
Croatian: VIAGRA može imati mali utjecaj na sposobnost upravljanja vozilima i rada sa strojevima.
English: VIAGRA potentiates the hypotensive effect of nitrates (see section 4.3).
Croatian: VIAGRA pojačava hipotenzivne učinke nitrata (vidjeti dio 4.3).
English: Certain patients have experienced these symptoms when taking VIAGRA with alpha-blockers.
Croatian: Određeni bolesnici imali su te simptome prilikom uzimanja lijeka VIAGRA s alfa-blokatorima.
English: VIAGRA with alcohol
Croatian: VIAGRA s alkoholom
English: Do not take VIAGRA with other medicines unless your doctor tells you that you can.
Croatian: Nemojte uzimati lijek VIAGRA s drugim lijekovima, osim ako Vam tako nije rekao liječnik.
English: Many events were reported to occur during or shortly after sexual intercourse and a few were reported to occur shortly after the use of VIAGRA without sexual activity.
Croatian: Za mnoge događaje prijavljeno je da su nastupili za vrijeme ili ubrzo nakon spolnog odnosa, a za nekolicinu da su nastali ubrzo nakon primjene lijeka VIAGRA bez spolne aktivnosti.
English: VIAGRA can cause dizziness and can affect vision.
Croatian: VIAGRA može uzrokovati omaglicu i utjecati na vid.
English: If you currently have a stomach ulcer, or a bleeding problems (such as haemophilia).
Croatian: Ako trenutno imate čir na želucu ili probleme s krvarenjem (kao što je hemofilija).
English: VIAGRA tablets may interfere with some medicines, especially those used to treat chest pain.
Croatian: VIAGRA tablete mogu međusobno djelovati s nekim lijekovima, osobito onima koji se koriste za liječenje boli u prsima.
English: In the event of a medical emergency, you should tell your doctor, pharmacist or nurse that you have taken VIAGRA and when you did.
Croatian: U slučaju hitne medicinske intervencije, morate upozoriti svog liječnika, ljekarnika ili medicinsku sestru da ste uzeli lijek VIAGRA te kada ste ga uzeli.
English: Viagra should be taken as needed approximately one hour before sexual activity.
Croatian: Viagra se treba uzimati po potrebi približno jedan sat prije spolne aktivnosti.
English: The safety profile of VIAGRA is based on 9,570 patients in 74 double-blind placebo-controlled clinical studies.
Croatian: Profil sigurnosti lijeka VIAGRA temelji se na podacima dobivenim od 9570 bolesnika koji su sudjelovali u 74 dvostruko slijepa, placebom kontrolirana klinička ispitivanja.
English: Children and adolescents VIAGRA should not be given to individuals under the age of 18.
Croatian: VIAGRA se ne smije davati osobama mlađim od 18 godina.
English: You should not take VIAGRA if you are a woman.
Croatian: Ne smijete uzimati lijek VIAGRA ako ste žena.
English: Paediatric population VIAGRA is not indicated for individuals below 18 years of age.
Croatian: Pedijatrijska populacija VIAGRA nije indicirana za primjenu u osoba mlađih od 18 godina.
English: VIAGRA is a treatment for adult men with erectile dysfunction, sometimes known as impotence.
Croatian: VIAGRA je lijek namijenjen liječenju odraslih muškaraca s erektilnom disfunkcijom, ponekad zvanom impotencija.
English: What VIAGRA contains
Croatian: Što VIAGRA sadrži
English: As dizziness and altered vision were reported in clinical trials with sildenafil, patients should be aware of how they react to VIAGRA, before driving or operating machinery.
Croatian: Budući da su omaglica i poremećaj vida zabilježeni u kliničkim ispitivanjima sa sildenafilom, bolesnici moraju biti svjesni na koji način oni reagiraju na lijek VIAGRA prije upravljanja vozilima ili rada sa strojevima.
English: Place the orodispersible tablet in the mouth, on the tongue, where it will dissolve in seconds, then swallow with saliva or water.
Croatian: Stavite raspadljivu tabletu za usta u usta, na jezik gdje će se rastopiti u roku od nekoliko sekundi, zatim progutajte sa slinom ili vodom.
English: Patients should be advised that in the event of any sudden visual defect, they should stop taking VIAGRA and consult a physician immediately (see section 4.3).
Croatian: Bolesnike treba savjetovati da u slučaju bilo kakvog iznenadnog poremećaja vida prestanu uzimati lijek VIAGRA i odmah zatraže savjet liječnika (vidjeti dio 4.3).
English: If you have a severe heart or liver problem.
Croatian: Ako imate teške probleme sa srcem ili jetrom.
English: VIAGRA is indicated in adult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
Croatian: VIAGRA je indicirana u odraslih muškaraca s erektilnom disfunkcijom, odnosno nemogućnošću postizanja ili održavanja penilne erekcije dostatne za zadovoljavajuću seksualnu aktivnost.
English: If VIAGRA is taken with food, the onset of activity may be delayed compared to the fasted state (see section 5.2).
Croatian: Ako se VIAGRA uzima s hranom, nastup djelovanja može biti odgođen u usporedbi s uzimanjem natašte (vidjeti dio 5.2).
English: Date of first authorisation: 14 September 1998 Date of latest renewal: 14 September 2008
Croatian: Datum posljednje obnove : 14. rujna 2008.
English: Due to age-differences in plasma protein binding, the corresponding increase in free sildenafil plasma concentration was approximately 40%.
Croatian: Zbog dobnih razlika u vezanju na proteine plazme, odgovarajući porast koncentracija slobodnog sildenafila u plazmi iznosio je približno 40%.
English: What VIAGRA is and what it is used for What you need to know before you take VIAGRA How to take VIAGRA
Croatian: Što je VIAGRA i za što se koristi Što morate znati prije nego počnete uzimati lijek VIAGRA
English: Rare ( 1/10,000 and <1/1,000)
Croatian: Rijetko ( 1/10 000 do <1/1000)
English: If you are allergic to sildenafil or any of the other ingredients of this medicine (listed in section 6).
Croatian: - ako ste alergični na sildenafil ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
English: VIAGRA is not indicated for use by women.
Croatian: VIAGRA nije namijenjena za primjenu u žena.
English: The orodispersible tablet should be placed in the mouth, on the tongue, and allowed to disintegrate before swallowing with or without water.
Croatian: Raspadljiva tableta za usta treba se staviti u usta, na jezik, pričekati da se rastopi prije nego se proguta, sa ili bez vode.
English: Pharmacotherapeutic group: Urologicals; Drugs used in erectile dysfunction, ATC Code: G04B E03.
Croatian: Farmakoterapijska skupina: urološki preparati; lijekovi koji se primjenjuju kod erektilne disfunkcije, ATK oznaka: G04B E03
English: VIAGRA is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure (see section 4.4).
Croatian: VIAGRA je kontraindicirana u bolesnika koji su izgubili vid na jednom oku zbog nearteritične anteriorne ishemijske optičke neuropatije (NAION), bez obzira je li ta epizoda bila u vezi ili ne s prethodnom izloženošću PDE5 inhibitoru (vidjeti dio 4.4).
English: What you need to know before you take VIAGRA
Croatian: Što morate znati prije nego počnete uzimati lijek VIAGRA
English: The film coating of the tablet contains lactose.
Croatian: Film ovojnica tablete sadrži laktozu.
English: PDE5 inhibitors, such as Viagra have been shown to increase the hypotensive effects of this medicine.
Croatian: PDE5 inhibitori, kao što je Viagra su pokazali da povećavaju hipotenzivne učinke ovog lijeka.
English: In the same study, the AUC was unchanged but the mean Cmax was 14% lower when 50 mg orodispersible tablets were administered with water compared to 50 mg film-coated tablet.
Croatian: U istom ispitivanju AUC je bio neizmijenjen, ali srednji Cmax bio je 14% niži kada su raspadljive tablete za usta od 50 mg primijenjene s vodom u usporedbi s filmom obloženom tabletom od 50 mg.
English: You should not take VIAGRA if you do not have erectile dysfunction.
Croatian: Ne smijete uzimati lijek VIAGRA ako nemate poremećaj erekcije.
English: If you experience any of the following serious side effects stop taking VIAGRA and seek medical help immediately:
Croatian: Ako primijetite bilo koju od sljedećih nuspojava, prestanite uzimati lijek VIAGRA i odmah zatražite medicinsku pomoć:
English: The active substance is sildenafil.
Croatian: - Djelatna tvar je sildenafil.
English: The manufacturer of VIAGRA is Fareva Amboise, Zone Industrielle, 29 route des Industries, 37530 Pocé-sur-Cisse, France.
Croatian: Proizvođač lijeka VIAGRA je Fareva Amboise, Zone Industrielle, 29 route des Industries, 37530 Pocé-sur-Cisse, Francuska.
English: If you require a second 50 mg orodispersible tablet to make a 100 mg dose, you should wait until the first one has completely disintegrated and you have swallowed it before taking the second orodispersible tablet.
Croatian: Ako trebate uzeti drugu 50 mg raspadljivu tabletu za usta kako biste postigli dozu od 100 mg, trebate pričekati da se prva potpuno rastopi u ustima i da je progutate prije uzimanja druge raspadljive tablete za usta.
English: The safety and efficacy of combinations of sildenafil with other PDE5 Inhibitors, or other pulmonary arterial hypertension (PAH) treatments containing sildenafil (REVATIO), or other treatments for erectile dysfunction have not been studied.
Croatian: Sigurnost i djelotvornost kombinacija sildenafila s drugim inhibitorima PDE5, s drugim terapijama za plućnu arterijsku hipertenziju (PAH) koje sadrže sildenafil (REVATIO) ili s drugim oblicima liječenja erektilne disfunkcije nije ispitana.
English: Given sildenafil peak plasma concentrations of approximately 1 μM after recommended doses, it is unlikely that VIAGRA will alter the clearance of substrates of these isoenzymes.
Croatian: S obzirom da su nakon preporučenih doza vršne koncentracije sildenafila u plazmi približno 1 μM, nije vjerojatno da će VIAGRA promijeniti klirens supstrata tih izoenzima.
English: If a dose of 25 mg is required, the use of the 25 mg film-coated tablets should be recommended.
Croatian: Ako je potrebna doza od 25 mg, preporučuje se primjena filmom obložene tablete od 25 mg.
English: If you have ever had loss of vision due to non-arteritic anterior ischaemic optic neuropathy (NAION).
Croatian: Ako ste ikada imali gubitak vida zbog nearteritične anteriorne ishemijske optičke neuropatije (NAION).
English: The dosing recommendations described in ‘Use in adults' apply to patients with mild to moderate renal impairment (creatinine clearance = 30-80 mL/min).
Croatian: Preporuke za doziranje opisane pod „Primjena u odraslih osoba“ odnose se na bolesnike s blagim do umjerenim oštećenjem funkcije bubrega (klirens kreatinina= 30-80 ml/min).
English: VIAGRA contains the active substance sildenafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors.
Croatian: VIAGRA sadrži djelatnu tvar sildenafil koja pripada skupini lijekova pod nazivom inhibitori fosfodiesteraze tipa 5 (PDE5).
English: Epidermal Necrolysis (TEN)*
Croatian: Stevens-Johnsonov sindrom (SJS)*, toksična epidermalna nekroliza (TEN)*
English: The side effects reported in association with the use of VIAGRA are usually mild to moderate and of a short duration.
Croatian: Nuspojave zabilježene kod primjene lijeka VIAGRA obično su blage do umjerene i kratko traju.
English: In the table below all medically important adverse reactions, which occurred in clinical trials at an incidence greater than placebo are listed by system organ class and frequency (very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000).
Croatian: U donjoj tablici navedene su sve medicinski značajne nuspojave koje su se javile u kliničkim ispitivanjima s incidencijom većom nego kod placeba razvrstane prema organskim sustavima i učestalosti (vrlo često (≥1/10), često (≥1/100 do <1/10), manje često (≥1/1000 do <1/100), rijetko (≥1/10 000 do <1/1000)).
English: If you experience sudden decrease or loss of vision, stop taking VIAGRA and contact your doctor immediately.
Croatian: Ako osjetite iznenadno slabljenje ili gubitak vida, prestanite uzimati lijek VIAGRA i odmah zatražite savjet liječnika.
English: The orodispersible tablets should be taken on an empty stomach as you may find that it takes longer to start working if you take it with a heavy meal.
Croatian: Raspadljivu tabletu za usta treba uzeti na prazan želudac jer, ako je uzmete uz obilniji obrok, možda će proći više vremena do početka njezinog djelovanja.
English: After a single oral dose of 100 mg, the mean maximum total plasma concentration of sildenafil is approximately 440 ng/mL (CV 40%).
Croatian: Nakon jednokratne oralne doze od 100 mg srednja maksimalna ukupna koncentracija sildenafila u plazmi iznosi približno 440 ng/ml(CV 40%).
English: In a clinical study in 36 healthy males 45 years or older, 50 mg orodispersible tablets administered without water were observed to be bioequivalent to the 50 mg film-coated tablets.
Croatian: U kliničkom ispitivanju na 36 zdravih muškaraca u dobi od 45 godina naviše zapaženo je da su raspadljive tablete za usta primijenjene bez vode biološki ekvivalentne filmom obloženim tabletama od 50 mg.
English: You should not use VIAGRA with treatments for pulmonary arterial hypertension (PAH) containing sildenafil or any other PDE5 inhibitors.
Croatian: Ne smijete uzimati lijek VIAGRA zajedno s terapijom za plućnu arterijsku hiperteniziju (PAH) koja sadrži sildenafil ili neke druge inhibitore PDE5.
English: You should take VIAGRA about one hour before you plan to have sex.
Croatian: Trebate uzeti lijek VIAGRA oko jedan sat prije planirane spolne aktivnosti.
English: The mean AUC and Cmax of the N-desmethyl metabolite increased up to 126% and up to 73% respectively, compared to age-matched volunteers with no renal impairment.
Croatian: Srednja AUC i Cmax N-dezmetil metabolita porasla je do 126% odnosno do 73% u usporedbi s dobrovoljcima odgovarajućim po dobi, bez oštećenja bubrega.
English: The recommended dose is 50 mg taken on an empty stomach as concomitant intake with food delays absorption and delays the effect of the orodispersible tablet (see section 5.2).
Croatian: Preporučena doza iznosi 50 mg i uzima se na prazan želudac jer istovremena primjena s hranom odgađa djelovanje raspadljive tablete za usta (vidjeti dio 5.2).
English: The European Medicines Agency has waived the obligation to submit the results of studies with VIAGRA in all subsets of the paediatric population for the treatment of erectile dysfunction.
Croatian: Europska Agencija za lijekove je izuzela obvezu podnošenja rezultata ispitivanja lijeka VIAGRA u svim podskupinama pedijatrijske populacije u svrhu liječenja erektilne disfunkcije (vidjeti dio 4.2 za informacije o pedijatrijskoj primjeni).
English: Do not store above 30oC.
Croatian: Ne čuvati na temperaturi iznad 30°C.
English: Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.
Croatian: Detaljnije informacije o ovom lijeku dostupne su na web stranici Europske agencije za lijekove: http://www.ema.europa.eu/
English: Warnings and precautions Talk to your doctor, pharmacist or nurse before taking VIAGRA If you have sickle cell anaemia (an abnormality of red blood cells), leukaemia (cancer of blood cells), multiple myeloma (cancer of bone marrow).
Croatian: Obratite se svom liječniku, ljekarniku ili medicinskoj sestri prije nego uzmete lijek VIAGRA: - Ako imate anemiju srpastih stanica (poremećaj crvenih krvnih stanica), leukemiju (rak krvnih stanica), multipli mijelom (rak koštane srži).
English: Since sildenafil (and its major circulating N-desmethyl metabolite) is 96% bound to plasma proteins, this results in the mean maximum free plasma concentration for sildenafil of 18 ng/mL (38 nM).
Croatian: Budući da je sildenafil (i njegov glavni cirkulirajući N-dezmetil metabolit) 96% vezan na proteine u plazmi, to rezultira srednjom maksimalnom koncentracijom slobodnog sildenafila u plazmi od 18 ng/ml(38 nM).
English: Serious cardiovascular events, including myocardial infarction, unstable angina, sudden cardiac death, ventricular arrhythmia, cerebrovascular haemorrhage, transient ischaemic attack, hypertension and hypotension have been reported post-marketing in temporal association with the use of VIAGRA.
Croatian: Ozbiljni kardiovaskularni događaji, uključujući infarkt miokarda, nestabilnu anginu, iznenadnu srčanu smrt, ventrikularnu aritmiju, cerebrovaskularno krvarenje, tranzitornu ishemijsku ataku, hipertenziju i hipotenziju bili su prijavljeni u razdoblju nakon stavljanja lijeka u promet, kao vremenski povezani s primjenom lijeka VIAGRA.
English: The maximum recommended dose is 100 mg.
Croatian: Najveća preporučena doza je 100 mg.
English: Tell your doctor if you are taking any of these medicines which are often given for relief of angina pectoris (or “chest pain”).
Croatian: Obavijestite svog liječnika ako uzimate bilo koji od ovih lijekova koji se često koriste za ublažavanje angine pektoris (ili "boli u prsima").
English: Riociguat: Preclinical studies showed additive systemic blood pressure lowering effect when PDE5 inhibitors were combined with riociguat.
Croatian: Riocigvat: Pretklinička ispitivanja su pokazala aditivan učinak na snižavanje krvnog tlaka kada su se PDE5 inhibitori koriste u kombinaciji sa riocigvatom.
English: If you are taking medicines known as protease inhibitors, such as for the treatment of HIV, your doctor may start you on the lowest dose (25 mg) of VIAGRA.
Croatian: Ako uzimate lijekove poznate kao inhibitori proteaze, na primjer za liječenje infekcije HIV-om, liječnik Vam može propisati najnižu početnu dozu (25 mg) lijeka VIAGRA.
English: There is a significant delay in absorption when orodispersible tablets are taken with a high fat meal compared to the fasted state (see section 5.2).
Croatian: Dolazi do znatne odgode djelovanja kada se raspadljive tablete za usta uzimaju s jelom koje sadrži visoku količinu masnoća u usporedbi sa stanjem natašte (vidjeti dio 5.2).
English: Do not take VIAGRA film-coated tablets in combination with VIAGRA orodispersible tablets.
Croatian: Nemojte uzeti VIAGRA filmom obložene tablete u kombinaciji s VIAGRA raspadljivim tabletama za usta.
English: Healthy, elderly volunteers (65 years or over) had a reduced clearance of sildenafil, resulting in approximately 90% higher plasma concentrations of sildenafil and the active N-desmethyl metabolite compared to those seen in healthy younger volunteers (18-45 years).
Croatian: Zdravi, stariji dobrovoljci (65 godina ili stariji) imali su smanjeni klirens sildenafila što je rezultiralo približno 90% višim koncentracijama sildenafila i aktivnog N-dezmetil metabolita u plazmi u usporedbi s koncentracijama opaženim u zdravih mlađih dobrovoljaca (18-45 godina).
English: Glycerol (E422) Propylene glycol (E1520)
Croatian: Prirodna aroma sadrži: maltodekstrin glicerol (E422) propilenglikol (E1520)
English: Always tell your doctor, pharmacist or nurse if you are taking any of these medicines that are often used for the relief of angina pectoris (or “chest pain”).
Croatian: Uvijek obavijestite svog liječnika, ljekarnika ili medicinsku sestru ako uzimate bilo koji od ovih lijekova koji se često koriste za ublažavanje angine pektoris (ili "boli u prsima“).
English: VIAGRA contains lactose
Croatian: VIAGRA sadrži laktozu
English: When orodispersible tablets is taken with a high fat meal, the rate of absorption of sildenafil is reduced, median Tmax is delayed by about 3.4 hours and mean Cmax and AUC are reduced respectively by about 59% and 12%, compared to administration of orodispersible tablets under fasting conditions (See Section 4.2).
Croatian: Kada su raspadljive tablete za usta uzete s jelom s visokim sadržajem masnoća, stopa apsorpcije sildenafila je smanjena, medijan tmax je odgođen za približno 3,4 sata, a srednji Cmax je smanjen za približno 59% u usporedbi s primjenom raspadljivih tableta za usta natašte (vidjeti dio 4.2).
English: Do not take VIAGRA orodispersible tablets in combination with film-coated tablets containing sildenafil including VIAGRA film-coated tablets.
Croatian: Nemojte uzeti VIAGRA raspadljive tablete za usta u kombinaciji s filmom obloženim tabletama koje sadrže sildenafil, uključujući VIAGRA filmom obložene tablete.
English: Alpha-tocopherol (E307)
Croatian: Aroma limuna sadrži: maltodekstrin alfa-tokoferol (E307)
English: Visual colour distortions**, Visual disturbance, Vision blurred
Croatian: Vizualni poremećaj percepcije boja**, Poremećaji vida, zamagljeni vid
English: If you are taking medicines known as protease inhibitors, such as for the treatment of HIV, your doctor may start you on the lowest dose (25 mg film-coated tablets) of VIAGRA.
Croatian: Ako uzimate lijekove poznate kao inhibitori proteaze, na primjer za liječenje infekcije HIV-om, liječnik Vam može propisati najnižu početnu dozu (25 mg filmom obložene tablete) lijeka VIAGRA.
English: Your doctor may start you on a lower dose (25 mg film-coated tablets) of VIAGRA.
Croatian: Liječnik Vas može staviti na početnu nižu dozu (25 mg filmom obložene tablete) lijeka VIAGRA.
English: Your doctor may start you on a lower dose (25 mg) of VIAGRA.
Croatian: Liječnik Vas može staviti na početnu nižu dozu (25 mg) lijeka VIAGRA.
English: In three specific drug-drug interaction studies, the alpha-blocker doxazosin (4 mg and 8 mg) and sildenafil (25 mg, 50 mg, or 100 mg) were administered simultaneously to patients with benign prostatic hyperplasia (BPH) stabilized on doxazosin therapy.
Croatian: U tri specifična ispitivanja interakcije lijek-lijek alfa-blokator doksazosin (4 mg i 8 mg) i sildenafil (25 mg, 50 mg ili 100 mg) primijenjeni su istodobno u bolesnika s benignom hiperplazijom prostate (BHP) stabiliziranima na terapiji doksazosinom.