FrancophonIA/ELRC3.0 huggingface dataset:
English: One phase II, open label, multicentre clinical trial (study B2225) was conducted including 12 patients with DFSP treated with imatinib 800 mg daily.
Swedish: En öppen, multicenter, klinisk fas II-studie (studie B2225) utfördes på 12 patienter med DFSP som behandlades med imatinib 800 mg dagligen.
English: Biochemistry
Swedish: Biokemi
English: Severe liver toxicity was observed in dogs treated for 2 weeks, with elevated liver enzymes, hepatocellular necrosis, bile duct necrosis, and bile duct hyperplasia.
Swedish: Allvarlig levertoxicitet observerades hos hundar som behandlats i 2 veckor, med förhöjda leverenzymer, hepatocellulär nekros, gallgångsnekros och gallgångshyperplasi.
English: Active substances that may increase imatinib plasma concentrations Substances that inhibit the cytochrome P450 isoenzyme CYP3A4 activity (e.g. protease inhibitors such as indinavir, lopinavir/ritonavir, ritonavir, saquinavir, telaprevir, nelfinavir, boceprevir; azole antifungals including ketoconazole, itraconazole, posaconazole, voriconazole; certain macrolides such as erythromycin, clarithromycin and telithromycin) could decrease metabolism and increase imatinib concentrations.
Swedish: Substanser som hämmar aktiviteten av cytokrom P450-isoenzymet CYP3A4 (t.ex. proteashämmare såsom indinavir, lopinavir/ritonavir, ritonavir, saquinavir, telaprevir, nelfinavir, boceprevir, antimykotikum inkluderande ketokonazol, itrakonazol, posakonazol, vorikonazol, vissa makrolider såsom erytromycin, klaritromycin och telitromycin) kan minska metabolismen och öka koncentrationen av imatinib.
English: How long to take Imatinib medac Keep taking Imatinib medac every day for as long as your doctor tells you.
Swedish: Fortsätt att ta Imatinib medac varje dag så länge din läkare säger åt dig att göra det.
English: Rash pustular, contusion, sweating increased, urticaria, ecchymosis, increased tendency to bruise, hypotrichosis, skin hypopigmentation, dermatitis exfoliative, onychoclasis, folliculitis, petechiae, psoriasis, purpura, skin hyperpigmentation,
Swedish: Pustulöst utslag, kontusion, ökad svettning, urtikaria, ekkymos, ökad tendens till blåmärken, hypotrikos, hypopigmentering av huden, exfoliativ dermatit, spruckna naglar, follikulit, petekier, psoriasis, purpura, hyperpigmentering av huden, bullöst utslag
English: Five (5) patients with MDS/MPD associated with PDGFR gene re-arrangements were reported in 4 publications.
Swedish: Fem (5) patienter med MDS/MPD associerat med rearrangemang av PDGFR-genen har rapporterats i fyra publikationer.
English: G-CSF (5 μg/kg, SC): days 4-13 or until ANC > 1500 post nadir
Swedish: G-CSF (5 μg/kg, SC): dagar 4-13 eller tills ANC > 1 500 efter nadir
English: Posology for Ph+ ALL in children
Swedish: Dosering vid Ph+ ALL hos barn
English: • Pale skin, feeling tired and breathlessness and having dark urine (signs of low levels of red
Swedish: • Blekhet, trötthet och andfåddhet med mörk urin (tecken på låg nivå av röda blodkroppar).
English: Marketing Authorisation Holder medac
Swedish: Innehavare av godkännande för försäljning medac
English: Migraine, somnolence, syncope, peripheral neuropathy, memory impairment, sciatica, restless leg syndrome, tremor, cerebral haemorrhage
Swedish: Migrän, somnolens, synkope, perifer neuropati, nedsatt minnesförmåga, ischiassmärta, restless legs syndrom, tremor, hjärnblödning
English: • Do not breast-feed during the treatment with Imatinib medac as there is limited information on the distribution of imatinib into the breast milk.
Swedish: • Amma inte under behandling med Imatinib medac då det finns begränsat med information om
English: Ileus/intestinal obstruction*, gastrointestinal perforation*, diverticulitis*, gastric Hepatobiliary disorders
Swedish: Ingen känd frekvens: Ileus/tarmobstruktion*, gastrointestinal perforation*, divertikulit*, antrala kärlektasier (GAVE)*
English: Very common (may affect more than 1 in 10 people) or common (may affect up to 1 in 10 people):
Swedish: Mycket vanliga (kan förekomma hos fler än 1 av 10 personer) eller vanliga (kan förekomma hos upp till 1 av 10 personer):
English: Population pharmacokinetics
Swedish: Farmakokinetik i populationen
English: (24 h), day 1; Etoposide 250 mg/m i.v.
Swedish: (24 tim), dag 1; Etoposid 250 mg/m² i.v.
English: 10) Musculoskeletal pain and related events were more commonly observed in patients with CML than in GIST patients.
Swedish: 10) Muskel- och skelettsmärta och besläktade biverkningar sågs oftare hos patienter med KML än hos patienter med GIST.
English: Imatinib medac 100 mg hard capsules Each hard capsule contains 12.518 mg lactose monohydrate.
Swedish: Imatinib medac 100 mg hårda kapslar Varje hård kapsel innehåller 12,518 mg laktosmonohydrat.
English: Target organs for neoplastic changes were the kidneys, urinary bladder, urethra, preputial and clitoral gland, small intestine, parathyroid glands, adrenal glands and non-glandular stomach.
Swedish: Målorgan för neoplastiska förändringar var njurar, urinblåsa, urinrör, preputiala och klitorala körtlar, tunntarm, bisköldkörtlar, binjurekörtlar och icke-glandulär magsäck.
English: • Rash, red skin with blisters on the lips, eyes, skin or mouth, peeling skin, fever, raised red or purple skin patches, itching, burning sensation, pustular eruption (signs of skin problems).
Swedish: • Hudutslag, rodnad med blåsor på läppar, ögon, hud eller mun, flagning av huden, feber, upphöjda röda eller lila hudområden, klåda, brännande känsla, utslag med små varfyllda blåsor
English: The age of these patients ranged from 3 months to 4 years and imatinib was given at dose 50 mg daily or doses ranging from 92.5 to 340 mg/m daily.
Swedish: Åldern på dessa patienter sträckte sig från 3 månader till 4 år och imatinib gavs i en dos om 50 mg dagligen eller doser från 92,5 till 340 mg/m² dagligen.
English: Capsule shell
Swedish: Kapselskal Gelatin
English: These events can usually be managed with either a reduction of the dose or an interruption of treatment with imatinib, but can in rare cases lead to permanent discontinuation of treatment.
Swedish: Dessa händelser kan vanligen åtgärdas med antingen dosminskning eller uppehåll av behandlingen med imatinib.
English: The age of these patients ranged from 2 to 16 years and imatinib was given at dose 300 mg/m daily or doses ranging from 200 to 400 mg daily.
Swedish: Åldern på dessa patienter sträckte sig från 2 till 16 år och imatinib gavs i en dos om 300 mg/m² dagligen och doser från 200 till 400 mg dagligen.
English: Concomitant use of imatinib and medicinal products that induce CYP3A4 (e.g. dexamethasone, phenytoin, carbamazepine, rifampicin, phenobarbital or Hypericum perforatum, also known as St. John's Wort) may significantly reduce exposure to imatinib, potentially increasing the risk of therapeutic failure.
Swedish: Samtidig användning av imatinib och läkemedel som inducerar CYP3A4 (t.ex. dexametason, fenytoin, karbamazepin, rifampicin, fenobarbital eller Hypericum perforatum, även känd som johannesört) kan signifikant minska exponeringen för imatinib och därigenom öka risken för terapisvikt.
English: Dose adjustments for neutropenia and thrombocytopenia:
Swedish: Dosjustering vid neutropeni och trombocytopeni:
English: The most commonly reported (≥ 10 %) treatment-related adverse reactions were mild nausea, vomiting, diarrhoea, abdominal pain, fatigue, myalgia, muscle cramps and rash.
Swedish: De vanligast förekommande (≥ 10 %) behandlingsrelaterade biverkningarna var lätt illamående, kräkning, diarré, buksmärta, trötthet, myalgi, muskelkramper och hudutslag.
English: VP-16 (100 mg/m2/day, IV): days 1-5
Swedish: VP-16 (100 mg/m²/dag, IV): dagar 1-5
English: 9/l) and thrombocytopenias (platelet count < 50 x 10
Swedish: 9/l) och trombocytopeni (trombocytnivåer < 50 x 10
English: INFORMATION IN BRAILLE Imatinib medac 100 mg
Swedish: INFORMATION I PUNKTSKRIFT Imatinib medac 100 mg
English: Therefore, the use of imatinib in combination with other chemotherapeutic agents requires special precaution.
Swedish: Därför krävs särskild försiktighet vid användning av imatinib i kombination med andra kemoterapeutiska medel.
English: Imatinib medac 400 mg hard capsules Each hard capsule contains 50.072 mg lactose monohydrate.
Swedish: Imatinib medac 400 mg hårda kapslar Varje hård kapsel innehåller 50,072 mg laktosmonohydrat.
English: Positive genotoxic effects were obtained for imatinib in an in vitro mammalian cell assay (Chinese hamster ovary) for clastogenicity (chromosome aberration) in the presence of metabolic activation at a concentration of 125 μg/ml.Two intermediates of the manufacturing process, which are also present in the final product, are positive for mutagenesis in the Ames assay.
Swedish: Positiva genotoxiska effekter avseende klastogenicitet (kromosomavvikelser) erhölls i ett mammaliecellstest in vitro (Chinese hamster ovary) i närvaro av metabolisk aktivering vid en koncentration på 125 µg/ml.
English: MTX 15 mg intrathecal, day 1;
Swedish: MTX 15 mg intratekal, dag 1
English: Imatinib medac is also a treatment for adults for:
Swedish: Imatinib medac är även en behandling för vuxna för:
English: (24 h), day 1, and Ara-C 2 g/m i.v.
Swedish: (24 tim), dag 1, och Ara-C 2 g/m² i.v.
English: Stop imatinib until ANC ≥ 1.5 x 10
Swedish: Sätt ut imatinib till dess ANC ≥ 1,5 x 109/l och trombocyter ≥ 75 x 10
English: The age of these patients ranged from newborn to 14 years and imatinib was given at dose 50 mg daily or doses ranging from 400 to 520 mg/m daily.
Swedish: Åldern på dessa patienter sträckte sig från nyfödda till 14 år och imatinib gavs i en dos om 50 mg dagligen eller doser från 400 till 520 mg/m² dagligen.
English: Avascular necrosis/hip necrosis*, growth retardation in children* Renal and urinary disorders
Swedish: Ingen känd frekvens: Avaskulär nekros/höftnekros*, tillväxthämning hos barn* Njurar och urinvägar
English: (3 h, q 12 h), days 1-3; i.v.
Swedish: (3 tim, q 12 tim), dagar 1-3;
English: Ifosfamide (1.8 g/m2/day, IV): days 1-5
Swedish: Ifosfamid (1,8 g/m²/dag, IV): dagar 1-5
English: Posology for CML in paediatric patients Dosing for paediatric patients should be on the basis of body surface area (mg/m2).
Swedish: Doseringen för pediatriska patienter skall baseras på kroppsyta (mg/m²).
English: VCR (1.5 mg/m 2/day, IV): days 1, 29
Swedish: VCR (1,5 mg/m²/dag, IV): dagar 1, 29
English: Patients with advanced stages of malignancies may have numerous confounding medical conditions that make causality of adverse reactions difficult to assess due to the variety of symptoms related to the underlying disease, its progression, and the co-administration of numerous medicinal products.
Swedish: Patienter med avancerade maligniteter kan ha flera andra symtom relaterade till grundsjukdomen, dess progression och samtidig behandling med flera andra läkemedel vilket försvårar bedömningen av ett eventuellt orsakssamband vid misstänkt biverkan.
English: Induction therapy (de novo Ph+ ALL)
Swedish: Studie AAU02 Induktionsbehandling (de novo Ph+ ALL)
English: One open-label, multicentre, phase II clinical trial (study B2225) was conducted testing imatinib in diverse populations of patients suffering from life-threatening diseases associated with Abl, Kit or PDGFR protein tyrosine kinases.
Swedish: En öppen, multicenter, klinisk fas II-studie (studie B2225) som testade imatinib hos olika populationer av patienter med livshotande sjukdomar förknippade med Abl, Kit eller PDGFR-proteintyrosinkinaser genomfördes.
English: Thrombocythaemia, lymphopenia, bone marrow depression, eosinophilia,
Swedish: Trombocytemi, lymfopeni, benmärgsdepression, eosinofili, lymfadenopati
English: What Imatinib medac is and what it is used for What you need to know before you take Imatinib medac
Swedish: I denna bipacksedel finns information om följande: Vad du behöver veta innan du tar Imatinib medac
English: 9/l, repeat step 1 and resume imatinib at reduced dose of 400 mg.
Swedish: 9/l, upprepa steg 1 och återuppta imatinib i reducerad dos om 400 mg.
English: ARA-C (3 g/m2/dose q 12 h x 4, IV): days 2 and 3
Swedish: ARA-C (3 g/m²/dos q12tim x 4, IV): dagar 2 och 3
English: CPM (250 mg/m2/dose q12h x 4 doses, IV): days 3 and 4
Swedish: CPM (250 mg/m²/dos q12tim x 4 doser, iv): dagar 3 och 4
English: If you get any of the above, tell your doctor straight away.
Swedish: Meddela omedelbart din läkare om du får något av ovanstående.
English: Intensification block 2 (9 weeks)
Swedish: Intensifieringsblock 2 (9 veckor)
English: Intensification block 1 (9 weeks)
Swedish: Intensifieringsblock 1 (9 veckor)
English: Accelerated phase is an intermediate phase among the chronic phase and the onset of the blast crisis; it is considered as the first manifestation of resistance to therapy.
Swedish: Accelererad fas är en intermediär fas mellan den kroniska fasen och inledningen av blastkrisen.
English: Paediatric accelerated phase CML and blast crisis (starting dose 340 mg/m
Swedish: KML i accelererad fas och blastkris hos barn (startdos 340 mg/m²)
English: G-CSF (5 μg/kg, SC): days 5-14 or until ANC > 1500 post nadir Triple IT therapy (age-adjusted): days 1 and 15
Swedish: G-CSF (5 μg/kg, SC): dagar 5-14 eller tills ANC > 1 500 efter nadir Trippel IT terapi (åldersjusterad): dagar 1 och 15
English: Active substances that may have their plasma concentration altered by imatinib Imatinib increases the mean Cmax and AUC of simvastatin (CYP3A4 substrate) 2- and 3.5-fold, respectively, indicating an inhibition of the CYP3A4 by imatinib.
Swedish: Imatinib ökar genomsnittligt Cmax och AUC för simvastatin (CYP3A4-substrat) 2 respektive 3,5 gånger, vilket visar att CYP3A4 hämmas av imatinib.
English: DEX (6 mg/m 2/day, PO): days 1-5; 29-33 6-MP (75 mg/m 2/day, PO): days 1-56 Methotrexate (20 mg/m 2/week, PO): days 1, 8, 15, 22, 29, 36, 43, 50 G-CSF = granulocyte colony stimulating factor, VP-16 = etoposide, MTX = methotrexate, IV = intravenous, SC = subcutaneous, IT = intrathecal, PO = oral, IM = intramuscular, ARA-C = cytarabine, CPM = cyclophosphamide, VCR = vincristine, DEX = dexamethasone, DAUN = daunorubicin, 6-MP = 6-mercaptopurine, E.Coli L-ASP = L-asparaginase, PEG-ASP = PEG asparaginase, MESNA= 2-mercaptoethane sulfonate sodium, iii= or until MTX level is < 0.1 µM, q6h = every 6 hours, Gy= Gray
Swedish: G-CS = granulocyte colony stimulating factor, VP-16 = etoposid, MTX = metotrexat, IV = intravenös, SC = subkutan, IT = intratekal, PO = oral, IM = intramuskulär, ARA-C = cytarabin, CPM = cyklofosfamid, VCR = vinkristin, DEX = dexametason, DAUN = daunorubicin, 6-MP = 6-merkaptopurin, E.Coli L-ASP = L-asparaginas, PEG-ASP = PEG asparaginas, MESNA = 2-merkaptoetan sulfonat natrium, iii = eller tills MTX nivå är < 0,1 µM, q6tim = var 6:e timme, Gy = Gray
English: Hypertension, haematoma, subdural haematoma, peripheral coldness, hypotension, Raynaud's phenomenon
Swedish: Hypertoni, hematom, subduralhematom, perifer kyla, hypotoni, Raynauds
English: 9/l, repeat step 1 and resume imatinib at reduced dose of 300 mg.
Swedish: 9/l, upprepa steg 1 och återuppta imatinib i reducerad dos om 300 mg.
English: 9/l, repeat step 1 and resume imatinib at reduced dose of 260 mg/m
Swedish: 9/l, upprepa steg 1 och återuppta imatinib i reducerad dos om 260 mg/m².
English: • Feeling dizzy or weak.
Swedish: • Yrsel eller svaghet.
English: When and how to take Imatinib medac • Take Imatinib medac with a meal.
Swedish: När och hur skall man ta Imatinib medac?
English: Study AUS01
Swedish: Studie AJP01
English: Treatment of CML patients with imatinib has been associated with neutropenia or thrombocytopenia.
Swedish: Imatinib har förknippats med neutropeni eller trombocytopeni vid behandling av patienter med KML.
English: The starting dose is 600 mg to be taken as 6 capsules of 100 mg (or 1 capsule of 400 mg plus 2 capsules of 100 mg) once a day.
Swedish: • Om du behandlas för Ph+ ALL: är startdosen 600 mg som tas som 6 kapslar på 100 mg (eller 1 kapsel på 400 mg plus 2 kapslar på 100 mg) en gång dagligen.
English: Imatinib medac is a treatment for adults and children and adolescents for:
Swedish: Imatinib medac är en behandling för vuxna och barn och ungdomar för:
English: If you take more Imatinib medac than you should If you have accidentally taken too many capsules, talk to your doctor straight away.
Swedish: Om du har tagit för stor mängd av Imatinib medac Kontakta din läkare omedelbart om du av misstag tagit för många kapslar.
English: If any of these affects you severely, tell your doctor.
Swedish: Meddela din läkare om något av detta påverkar dig allvarligt.
English: If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Swedish: Imatinib medac innehåller laktosmonohydrat Om du inte tål vissa sockerarter, bör du kontakta din läkare innan du tar denna medicin.
English: • Severe abdominal pain, blood in your vomit, stools or urine, black stools (signs of
Swedish: • Svår buksmärta, blod i uppkastning, avföring eller urin, svartfärgad avföring (tecken på
English: Studies in animals have however shown reproductive toxicity (see section 5.3) and the potential risk for the foetus is unknown.
Swedish: Djurstudier har visat reproduktionstoxikologiska effekter (se avsnitt 5.3).
English: (n = 5), 340 mg/m2/day (n = 7) and 570 mg/m 2/day (n = 5).
Swedish: Patienterna behandlades med doser av imatinib om 260 mg/m²/dag (n = 5), 340 mg/m²/dag (n = 9), 440 mg/m²/dag (n = 7) och 570 mg/m²/dag (n = 5).
English: Musculoskeletal and connective tissue disorders Very common: Muscle spasm and cramps, musculoskeletal pain including myalgia
Swedish: Muskelspasm och kramper, muskel- och skelettsmärta inklusive myalgi
English: In the study in patients with unresectable and/or metastatic GIST, grade 3 and 4 anaemia was reported in 5.4 % and 0.7 % of patients, respectively, and may have been related to gastrointestinal or intratumoural bleeding in at least some of these patients.
Swedish: I studien på patienter med icke-resercerbar och/eller metastaserande GIST rapporterades anemier av grad 3 och 4 hos 5,4 % respektive 0,7 % av patienterna.
English: Maintenance
Swedish: Underhållsbehandling
English: • Joint pain with swelling.
Swedish: • Ledsmärta med svullnad.
English: Methotrexate (5 g/m over 24 hours, IV): day 1 Leucovorin (75 mg/m at hour 36, IV; 15 mg/m
Swedish: Metotrexat (5 g/m² över 24 timmar, IV): dagar 1 och 15 Leucovorin (75 mg/m² vid timme 36, IV; 15 mg/m² IV eller PO q6tim x 6
English: Active substances that may decrease imatinib plasma concentrations Substances that are inducers of CYP3A4 activity (e.g. dexamethasone, phenytoin, carbamazepine, rifampicin, phenobarbital, fosphenytoin, primidone or Hypericum perforatum, also known as St. John's Wort) may significantly reduce exposure to imatinib, potentially increasing the risk of therapeutic failure.
Swedish: Substanser som inducerar CYP3A4-aktivitet (t.ex. dexametason, fenytoin, karbamazepin, rifampicin, fenobarbital, fosfenytoin, primidon eller Hypericum perforatum, även känd som johannesört) kan signifikant minska exponeringen för imatinib och därigenom potentiellt öka risken för terapisvikt.
English: 9/l and/or platelets < 50 x 10
Swedish: 9/l och/eller trombocyter < 50 x 10
English: The capsule shell for 100 mg capsule is composed of gelatine, yellow iron oxide (E172), titanium dioxide (E171) and red iron oxide (E172).
Swedish: Kapselskalet (för 100 mg kapsel) består av gelatin, gul järnoxid (E172), titandioxid (E171) och röd järnoxid (E172).
English: Posology for CML in adult patients
Swedish: Dosering vid KML hos vuxna
English: • Feeling sick (nausea) with diarrhoea and vomiting, abdominal pain or fever (signs of bowel
Swedish: • Illamående, med diarré och kräkningar, buksmärta eller feber (tecken på tarmproblem).
English: Skin and subcutaneous tissue disorders Very common: Periorbital oedema, dermatitis/eczema/rash
Swedish: Periorbitalt ödem, dermatit/eksem/utslag
English: The no observed effect level (NOEL) was 15 mg/kg/day.
Swedish: NOEL var 15 mg/kg/dag.
English: • Bruising.
Swedish: • Näsblödning.
English: The capsule shell for 400 mg capsule is composed of gelatine, yellow iron oxide (E172), titanium dioxide (E171), red iron oxide (E172) and black iron oxide (E172).
Swedish: Kapselskalet (för 400 mg kapsel) består av gelatin, gul järnoxid (E172), titandioxid (E171), röd järnoxid (E172) och svart järnoxid (E172).
English: Haematological response criteria (all responses to be confirmed after ≥ 4 weeks): CHR:
Swedish: Hematologiska svarskriterier (alla svar skall bekräftas efter ≥ 4 veckor): FHS I studie 0102 (ANC ≥ 1,5 x 10
English: Accelerated phase is an intermediate phase among the chronic phase and the onset of blast crisis; it is considered as the first manifestation of resistance to therapy.
Swedish: Accelererad fas anses vara den första manifestationen av terapiresistens.
English: Maximal plasma concentrations of imatinib in patients are 2-4 μmol/l, consequently an inhibition of CYP2D6 and/or CYP3A4/5-mediated metabolism of co-administered medicinal products is possible.
Swedish: Följaktligen är en hämning av CYP2D6- och/eller CYP3A4/5-medierad metabolism möjlig av samtidigt givna läkemedel.
English: Gynaecomastia, erectile dysfunction, menorrhagia, menstruation irregular, sexual dysfunction, nipple pain, breast enlargement, scrotal oedema
Swedish: Gynekomasti, erektil dysfunktion, menorragi, oregelbunden menstruation, sexuell dysfunktion, ömma bröstvårtor, bröstförstoring, skrotumödem
English: Common: Uncommon:
Swedish: Vanliga: Mindre vanliga:
English: Imatinib medac 100 mg hard capsules Imatinib medac 400 mg hard capsules
Swedish: Imatinib medac 100 mg hårda kapslar Imatinib medac 400 mg hårda kapslar
English: Nervous system disorders
Swedish: Förvirring Centrala och perifera nervsystemet
English: Consolidation therapy DEX 10 mg/m oral, days 1-5; Vindesine 3 mg/m i.v., day 1;
Swedish: DEX 10 mg/m² oral, dagar 1-5; Vindesin 3 mg/m² i.v., dag 1;
English: Reinduction block 2 (3 weeks)
Swedish: Reinduktionsblock 2 (3 veckor)
English: Reinduction block 1 (3 weeks)
Swedish: Reinduktionsblock 1 (3 veckor)
English: • Nausea, shortness of breath, irregular heartbeat, clouding of urine, tiredness and/or joint discomfort associated with abnormal laboratory test results (eg.
Swedish: • Illamående, andfåddhet, oregelbundna hjärtslag, grumlig urin, trötthet och/eller ledbesvär associerat med onormala laboratorievärden (t.ex. höga kalium-, urinsyra- och kalciumnivåer,
English: (q 12 h), days 2-3, for
Swedish: (q 12 tim), dagar 2-3, i 4 cykler
English: If this applies to you, tell your doctor without taking Imatinib medac.
Swedish: Om detta gäller dig, ta inte Imatinib medac utan meddela din läkare.
English: 1, sinusitis, cellulitis, upper respiratory tract infection, influenza, urinary tract infection, gastroenteritis, sepsis
Swedish: Herpes zoster, herpes simplex, nasofaryngit, pneumoni1, sinuit, celluliter, övre luftvägsinfektion, influensa, urinvägsinfektion, gastroenterit, sepsis
English: Laboratory test abnormalities
Swedish: Avvikelser i laboratorieundersökningar:
English: • Swelling such as round your ankles or puffy eyes.
Swedish: • Svullnad runt leder eller uppsvullna ögon.
English: The no observed effect level (NOEL) was 30 mg/kg/day.
Swedish: NOEL var 30 mg/kg/dag.
English: Imatinib medac is also a treatment for children and adolescents for:
Swedish: Imatinib medac är även en behandling för barn och ungdomar för:
English: Consolidation block 2 (3 weeks)
Swedish: Konsolideringsblock 2 (3 veckor)
English: Acute febrile neutrophilic dermatosis (Sweet's syndrome), nail discolouration, angioneurotic oedema, rash vesicular, erythema multiforme, leucocytoclastic vasculitis, Stevens-Johnson syndrome, acute generalised exanthematous pustulosis
Swedish: Akut febril neutrofil dermatos (Sweet's syndrom), missfärgning av naglar, angioödem, vesikulärutslag, erytema multiforme, leukocytoklastisk vaskulit, Stevens-Johnsons syndrom, AGEP (akut generaliserad exantematös pustulos) Ingen känd frekvens: Palmar-plantar erytrodysestesi syndrom*, likenoid keratos*, lichen planus*, toxisk epidermal nekrolys*, läkemedelsrelaterade utslag med eosinofili och
English: Organ function impairment
Swedish: Organfunktionsnedsättning
English: (1 h), days 28-31, 35-38, 42-45;
Swedish: (1 tim), dagar 28-31,