FrancophonIA/ELRC3.0 huggingface dataset:
English: Aranesp 500 micrograms solution for injection in pre-filled pen 1 mL solution for injection (500 mcg/mL darbepoetin alfa) in a pre-filled pen with type 1 glass syringe and stainless steel 27 gauge needle.
Croatian: Aranesp 500 mikrograma otopina za injekciju u napunjenoj brizgalici 1 ml otopine za injekciju (500 µg/ml darbepoetina alfa) u napunjenoj brizgalici sa štrcaljkom od stakla tipa 1 i iglom od 27 gauge od nehrđajućeg čelika.
English: A sustained haemoglobin level of greater than 12 g/dL (7.5 mmol/L) should be avoided; guidance for appropriate dose adjustment for when haemoglobin values exceeding 12 g/dL (7.5 mmol/L) are observed are described below.
Croatian: Mora se izbjeći kontinuirano održanu vrijednost hemoglobina veću od 12 g/dl (7,5 mmol/l).
English: Aranesp 20 micrograms solution for injection in pre-filled pen 0.5 mL solution for injection (40 mcg/mL darbepoetin alfa) in a pre-filled pen with type 1 glass syringe and stainless steel 27 gauge needle.
Croatian: Aranesp 20 mikrograma otopina za injekciju u napunjenoj brizgalici 0,5 ml otopine za injekciju (40 µg/ml darbepoetina alfa) u napunjenoj brizgalici sa štrcaljkom od stakla tipa 1 i iglom od 27 gauge od nehrđajućeg čelika.
English: EU/1/01/185/009 1 pack EU/1/01/185/010 4 pack EU/1/01/185/082 1 pack with needle guard EU/1/01/185/083 4 pack with needle guard
Croatian: EU/1/01/185/082 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/083 pakiranje od 1 sa štitnikom za iglu
English: Aranesp 60 micrograms solution for injection in pre-filled pen 0.3 mL solution for injection (200 mcg/mL darbepoetin alfa) in a pre-filled pen with type 1 glass syringe and stainless steel 27 gauge needle.
Croatian: Aranesp 60 mikrograma otopina za injekciju u napunjenoj brizgalici 0,3 ml otopine za injekciju (200 µg/ml darbepoetina alfa) u napunjenoj brizgalici sa štrcaljkom od stakla tipa 1 i iglom od 27 gauge od nehrđajućeg čelika.
English: MARKETING AUTHORISATION NUMBER(S) EU/1/01/185/053 1 pack
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/01/185/053 pakiranje od 1
English: EU/1/01/185/018 4 Pack Blister
Croatian: EU/1/01/185/018 pakiranje od 4
English: EU/1/01/185/019 1 pack EU/1/01/185/020 4 pack EU/1/01/185/094 1 pack with needle guard EU/1/01/185/095 4 pack with needle guard
Croatian: EU/1/01/185/094 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/095 pakiranje od 4 sa štitnikom za iglu
English: EU/1/01/185/021 1 pack EU/1/01/185/022 4 pack EU/1/01/185/096 1 pack with needle guard EU/1/01/185/097 4 pack with needle guard
Croatian: EU/1/01/185/096 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/097 pakiranje od 4 sa štitnikom za iglu
English: Aranesp 30 micrograms solution for injection in pre-filled pen Each pre-filled pen contains 1.14 mg of sodium in 0.3 mL.
Croatian: Aranesp 30 mikrograma otopina za injekciju u napunjenoj brizgalici Jedna napunjena brizgalica sadrži 1,14 mg natrija u 0,3 ml.
English: Thromboembolic eventsc
Croatian: ATK oznaka: B03XA02
English: Aranesp 300 micrograms solution for injection in pre-filled pen 0.6 mL solution for injection (500 mcg/mL darbepoetin alfa) in a pre-filled pen with type 1 glass syringe and stainless steel 27 gauge needle.
Croatian: Aranesp 300 mikrograma otopina za injekciju u napunjenoj brizgalici 0,6 ml otopine za injekciju (500 µg/ml darbepoetina alfa) u napunjenoj brizgalici sa štrcaljkom od stakla tipa 1 i iglom od 27 gauge od nehrđajućeg čelika.
English: EU/1/01/185/011 1 pack EU/1/01/185/012 4 pack EU/1/01/185/084 1 pack with needle guard EU/1/01/185/085 4 pack with needle guard
Croatian: EU/1/01/185/084 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/085 pakiranje od 4 sa štitnikom za iglu
English: EU/1/01/185/069 1 pack EU/1/01/185/070 4 pack EU/1/01/185/092 1 pack with needle guard EU/1/01/185/093 4 pack with needle guard
Croatian: EU/1/01/185/092 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/093 pakiranje od 4 sa štitnikom za iglu
English: Aranesp 80 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 80 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: Aranesp 60 micrograms solution for injection in pre-filled pen Each pre-filled pen contains 1.14 mg of sodium in 0.3 mL.
Croatian: Aranesp 60 mikrograma otopina za injekciju u napunjenoj brizgalici Jedna napunjena brizgalica sadrži 1,14 mg natrija u 0,3 ml.
English: Aranesp 10 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 10 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: Aranesp 100 micrograms solution for injection in pre-filled pen 0.5 mL solution for injection (200 mcg/mL darbepoetin alfa) in a pre-filled pen with type 1 glass syringe and stainless steel 27 gauge needle.
Croatian: Aranesp 100 mikrograma otopina za injekciju u napunjenoj brizgalici 0,5 ml otopine za injekciju (200 µg/ml darbepoetina alfa) u napunjenoj brizgalici sa štrcaljkom od stakla tipa 1 i iglom od 27 gauge od nehrđajućeg čelika.
English: Aranesp 50 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 50 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: EU/1/01/185/041 1 Pack Unblistered EU/1/01/185/090 1 blister pack with needle guard EU/1/01/185/091 4 blister pack with needle guard Aranesp 130 micrograms solution for injection pre-filled syringe EU/1/01/185/069 1 Pack Blister
Croatian: EU/1/01/185/090 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/091 pakiranje od 4 sa štitnikom za iglu
English: Aranesp 20 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 20 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: Aranesp 40 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 40 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: Aranesp 60 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 60 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: STATEMENT OF ACTIVE SUBSTANCE(S) Each 0.3 mL pre-filled pen contains 60 micrograms darbepoetin alfa (200 micrograms/mL).
Croatian: NAVOĐENJE DJELATNE(IH) TVARI Jedna napunjena brizgalica od 0,3 ml sadrži 60 mikrograma darbepoetina alfa (200 mikrograma/ml).
English: EU/1/01/185/061 - 4 pack
Croatian: EU/1/01/185/061 - pakiranje od 4
English: EU/1/01/185/015 1 pack EU/1/01/185/016 4 pack EU/1/01/185/088 1 pack with needle guard EU/1/01/185/089 4 pack with needle guard
Croatian: EU/1/01/185/088 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/089 pakiranje od 4 sa štitnikom za iglu
English: MARKETING AUTHORISATION NUMBER(S) EU/1/01/185/051 1 pack
Croatian: 12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/01/185/051 pakiranje od 1
English: Aranesp 30 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 30 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: EU/1/01/185/017 1 pack EU/1/01/185/018 4 pack EU/1/01/185/090 1 pack with needle guard EU/1/01/185/091 4 pack with needle guard
Croatian: EU/1/01/185/078 pakiranje od 1 sa štitnikom za iglu EU/1/01/185/079 pakiranje od 4 sa štitnikom za iglu
English: EU/1/01/185/070 4 Pack Blister
Croatian: EU/1/01/185/070 pakiranje od 4
English: • Stroke
Croatian: • Natkoljenica
English: Aranesp 100 micrograms solution for injection in pre-filled pen.
Croatian: Aranesp 100 mikrograma otopina za injekciju u napunjenoj brizgalici.
English: Subcutaneous use pre-filled syringe (glass)
Croatian: Napunjena štrcaljka (staklo)
English: Strength Pharmaceutical Form
Croatian: Doza Farmaceutski oblik Put primjene Unutarnje pakiranje
English: Solution for injection
Croatian: 6 mg Otopina za injekciju Potkožno
English: PC: {number} SN: {number} < NN: {number} >
Croatian: PC: {broj} SN: {broj} < NN: {broj} >
English: Otherwise, you may put yourself and others at risk of serious injury or death.
Croatian: U protivnom možete sebe i druge izložiti riziku od ozbiljne ozljede ili smrti.
English: After taking one of them, wait at least 2 to 3 hours before taking the other.
Croatian: Nakon uzimanja jednog od njih, pričekajte najmanje 2 do 3 sata prije nego uzmete drugi.
English: In individual cases, only some of these symptoms and/or findings may be evident.
Croatian: U pojedinačnim slučajevima mogu biti izraženi samo neki od ovih simptoma i/ili nalaza.
English: Accordingly, to date there has been no indication of such interactions.
Croatian: U skladu s tim, za sada nema naznake takvih interakcija.
English: - You should take only one tablet each time.
Croatian: - Svaki puta smijete uzeti samo jednu tabletu.
English: Your doctor may need to review your treatments.
Croatian: Vaš liječnik će možda trebati preispitati liječenje.
English: FI-02200 Espoo Finland
Croatian: FI-02200 Espoo Finska
English: [carton only]:
Croatian: [samo kutija]:
English: Consult your doctor if you think this applies to you.
Croatian: Obratite se svom liječniku ako mislite da se to odnosi na vas.
English: This may cause difficulties in breathing or swallowing.
Croatian: To može uzrokovati teškoće s disanjem ili gutanjem.
English: Dose reduction may be needed (see section 5.2).
Croatian: Smanjenje doze može biti potrebno (vidjeti dio 5.2).
English: After that carry on as normal.
Croatian: Nakon toga nastavite prema uobičajenom rasporedu.
English: - Depending on how you respond to treatment, your doctor may suggest a higher or lower dose.
Croatian: - Ovisno o tome kako reagirate na liječenje, liječnik može odrediti veću ili manju dozu.
English: The INR values increased on average by 13% [CI90 6-19%].
Croatian: Vrijednosti INR-a porasle su prosječno za 13% [CI90 6-19%].
English: - The tablets are not intended to be split or broken into smaller pieces.
Croatian: - Nije predviđeno da se tableta lomi ili dijeli na manje dijelove.
English: Dose adjustment during the course of the treatment
Croatian: Prilagođavanje doze tijekom liječenja
English: Take a tablet as soon as you remember, wait 1 hour, then take another tablet.
Croatian: Uzmite jednu tabletu čim se sjetite, pričekajte jedan sat i zatim uzmite drugu tabletu.
English: Date of first authorisation: 24 August 2011 Date of latest renewal: 26 May 2016
Croatian: Datum posljednje obnove odobrenja: 26. svibnja 2016.
English: Each tablet is to be taken orally either with or without food (see section 5.2).
Croatian: Svaka tableta uzima se peroralno sa ili bez hrane (vidjeti dio 5.2).
English: If required, appropriate anti-arrhythmic therapy should be given.
Croatian: Po potrebi treba dati odgovarajuću antiaritmičku terapiju.
English: There are no significant differences in the AUC of carbidopa or entacapone between younger (45-64 years) and elderly (65-75 years).
Croatian: Nema značajnih razlika u AUC karbidope ili entakapona između mlađih (45-64 godina) i starijih osoba (65-75 godina).
English: Neuroleptic malignant syndrome*
Croatian: Neuroleptički maligni sindrom*
English: Picture 1
Croatian: Slika 1
English: To open the bottle for the first time: open the closure, and then press with your thumb on the seal until it breaks.
Croatian: Pri prvom otvaranju bočice: uklonite zatvarač i zatim palcem pritisnite zaštitnu foliju tako da je probijete.
English: even if their symptoms signs of illness are the same as yours.
Croatian: Može im naškoditi, čak i ako su njihovi znakovi bolesti jednaki Vašima.
English: Weight decreased*, decreased appetite*
Croatian: Smanjenje tjelesne težine*, smanjenje apetita*
English: Tell your doctor if you experience any of these behaviours; they will discuss ways of managing or reducing the symptoms.
Croatian: Obavijestite svog liječnika ako imate bilo koje od tih ponašanja; on će razmotriti načine za suzbijanje ili ublažavanje simptoma.
English: One tablet contains one treatment dose and the tablet may only be administered as whole tablets.
Croatian: Jedna tableta sadrži jednu terapijsku dozu i smije ju se uzeti isključivo kao cijelu tabletu.
English: The optimum daily dose must be determined by careful titration of levodopa in each patient.
Croatian: Optimalna dnevna doza mora se odrediti pažljivim titriranjem levodope u svakog bolesnika.
English: If you feel very drowsy, or if you sometimes find yourself suddenly falling asleep, wait until you feel fully awake again before driving or doing anything else that requires you to be alert.
Croatian: Ako osjećate jaku pospanost ili ponekad iznenada zaspete, pričekajte da se potpuno razbudite prije nego počnete voziti ili raditi bilo što drugo što zahtijeva Vašu potpunu pozornost.
English: The requirements for submission of periodic safety update reports for this medicinal product are set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and any subsequent updates published on the European medicines web portal.
Croatian: Zahtjevi za podnošenje periodičkih izvješća o neškodljivosti za ovaj lijek definirani su u referentnom popisu datuma EU (EURD popis) predviđenom člankom 107.c stavkom 7. Direktive 2001/83/EZ i svim sljedećim ažuriranim verzijama objavljenima na europskom internetskom portalu za lijekove.
English: If it is more than 1 hour until your next dose: Take one tablet as soon as you remember, and the next tablet at the normal time.
Croatian: Ako sljedeću dozu trebate uzeti za više od jednog sata: Uzmite jednu tabletu čim se sjetite, a sljedeću tabletu prema uobičajenom rasporedu.
English: However, in an interaction study with healthy volunteers, entacapone did not change the plasma levels of S-warfarin, while the AUC for Rwarfarin increased on average by 18% [CI90 11-26%].
Croatian: Međutim, u jednom ispitivanju interakcija na zdravim dobrovoljcima, entakapon nije promijenio razine S-varfarina u plazmi, dok je AUC Rvarfarina porastao prosječno za 18% [CI90 11-26%].
English: Like all medicines, this medicine can cause side effects, although not everybody gets them.
Croatian: Kao i svi lijekovi, ovaj lijek može uzrokovati nuspojave iako se neće one javiti kod svakoga.
English: Consequently the clinical response to each dose of levodopa is enhanced and prolonged.
Croatian: Posljedično je klinički odgovor na svaku dozu levodope pojačan i produljen.
English: Studies in animals have shown reproductive toxicity of the separate compounds (see section 5.3).
Croatian: Ispitivanja na životinjama pokazala su reproduktivnu toksičnost pojedinačnih spojeva (vidjeti dio 5.3).
English: No pharmacodynamic interactions were observed.
Croatian: Nisu opažene farmakodinamičke interakcije.
English: Hepatitis with mainly cholestatic features (see section 4.4)*
Croatian: Hepatitis s uglavnom kolestatskim obilježjima (vidjeti dio 4.4)*
English: Rash*, hyperhidrosis
Croatian: Osip*, hiperhidroza
English: ECG monitoring should be started and the patient carefully monitored for the possible development of arrhythmias.
Croatian: Mora se započeti praćenje EKG-a i bolesnika treba pažljivo nadzirati radi mogućeg razvoja aritmija.
English: - Patients should be regularly monitored for the development of impulse control disorders.
Croatian: - Bolesnike treba redovito nadzirati zbog mogućeg razvoja poremećaja kontrole impulsa.
English: The main metabolic pathway is glucuronidation of entacapone and its active metabolite, the cis-isomer, which accounts for about 5% of plasma total amount.
Croatian: Glavni metabolički put je glukuronidacija entakapona i njegovog aktivnog metabolita, cis-izomera, koji čini oko 5% ukupne količine u plazmi.
English: See picture 1.
Croatian: Vidjeti sliku 1.
English: In such a case your doctor may need to adjust your other antiparkinson medicines, especially levodopa, to give sufficient control of your symptoms.
Croatian: U tom će slučaju liječnik možda trebati prilagoditi Vaše ostale antiparkinsonike, posebno levodopu, kako bi se postigla zadovoljavajuća kontrola Vaših simptoma.
English: Gender: Bioavailability of levodopa is significantly higher in women than in men.
Croatian: Spol: bioraspoloživost levodope je značajno viša u žena nego u muškaraca.
English: Adverse reactions are ranked under headings of frequency, the most frequent first, using the following convention: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000), very rare (<1/10,000), not known (cannot be estimated from the available data, since no valid estimate can be derived from clinical trials or epidemiological studies).
Croatian: Nuspojave su poredane prema učestalosti, pri čemu se na početku navode najčešće, koristeći sljedeće izraze: vrlo često (≥1/10); često (≥1/100 i <1/10); manje često (≥1/1000 i <1/100); rijetko (≥1/10 000 i <1/1000); vrlo rijetko (<1/10 000); nepoznato (ne može se procijeniti iz dostupnih podataka, jer se ne može izvesti valjana procjena iz kliničkih ispitivanja ili epidemioloških studija).
English: Therefore, be particularly careful when you drive or when you use any tools or machines.
Croatian: Stoga budite posebno oprezni kada vozite ili rukujete alatima ili strojevima.
English: This may hasten the elimination of entacapone in particular by decreasing its absorption/reabsorption from the GI tract.
Croatian: To može ubrzati eliminaciju entakapona, posebno smanjenjem njegove apsorpcije/reapsorpcije iz GI trakta.
English: Pharmacotherapeutic group: anti-parkinson drugs, dopa and dopa derivatives, ATC code: N04BA03
Croatian: Farmakoterapijska skupina: antiparkinsonici, dopa i derivati dope, ATK oznaka: N04BA03
English: Correspondingly, the decrease in daily OFF time was 24% in the entacapone group and 0% in the placebo group.
Croatian: U skladu s time, sniženje dnevnog trajanja "OFF" faze bilo je 24% u entakapon grupi i 0% u placebo grupi.
English: Meals rich in large neutral amino acids may delay and reduce the absorption of levodopa.
Croatian: Obroci bogati velikim neutralnim aminokiselinama mogu odgoditi i smanjiti apsorpciju levodope.
English: In the event of prolonged or persistent diarrhoea, the drug should be discontinued and appropriate medical therapy and investigations considered.
Croatian: Kod dugotrajne ili ustrajne dijareje, treba prekinuti davanje lijeka i razmotriti odgovarajuća liječenja i pretrage.
English: The value of dialysis in the treatment of overdose is not known.
Croatian: Vrijednost dijalize u liječenju predoziranja nije poznata.
English: Tell your doctor if you or your family/carer notices you are developing urges or cravings to behave in ways that are unusual for you or you cannot resist the impulse, drive or temptation to carry out certain activities that could harm yourself or others.
Croatian: Obavijestite svog liječnika ako Vi ili Vaša obitelj/skrbnik primijetite da se kod Vas razvija nagon i žudnja za ponašanjem na načine koji su za Vas neuobičajeni ili da se ne možete oduprijeti impulsu, porivu ili iskušenju za neke aktivnosti koje mogu biti štetne za Vas ili druge.
English: Unchanged carbidopa accounts for 30% of the total urinary excretion.
Croatian: Nepromijenjena karbidopa čini 30% ukupnog izlučivanja mokraćom.
English: This is translated to a mean increase of 35 min in the daily ON time.
Croatian: To se može prevesti u srednju vrijednost porasta od 35 min u dnevnom trajanju "ON" faze.
English: The early diagnosis is important for the appropriate management of NMS.
Croatian: Rana dijagnoza je važna zbog odgovarajućeg liječenja NMS-a.
English: See section c.
Croatian: Vidjeti dio c.
English: If it is less than 1 hour until your next dose:
Croatian: Ako sljedeću dozu trebate uzeti za manje od jednog sata:
English: Many of the side effects can be relieved by adjusting the dose.
Croatian: Mnoge se nuspojave mogu ublažiti prilagođavanjem doze.
English: Consult your doctor if you are currently taking: - antipsychotics (medicines used to treat psychosis) - a medicine which may cause low blood pressure when rising from a chair or bed.
Croatian: Savjetujte se sa svojim liječnikom ako trenutno uzimate: - antipsihotike (lijekovi za liječenje psihoze), - lijek koji može uzrokovati pad krvnog tlaka kada ustajete sa stolice ili kreveta.
English: In vitro data: Entacapone binds to human albumin binding site II which also binds several other medicinal products, including diazepam and ibuprofen.
Croatian: In vitro podaci: entakapon se veže na vezno mjesto II ljudskog albumina, na koje se također veže nekoliko drugih lijekova, uključujući diazepam i ibuprofen.
English: Entacapone may in some cases cause also discolouration of e.g. skin, nail, hair and sweat.
Croatian: Entakapon može u nekim slučajevima također izazvati diskoloraciju npr. kože, noktiju, kose i znoja.
English: Food does not significantly affect the absorption of entacapone.
Croatian: Hrana ne utječe značajno na apsorpciju entakapona.
English: However, no interaction with carbidopa has been observed with the recommended treatment schedule (200 mg of entacapone up to 10 times daily).
Croatian: Međutim, nije opažena interakcija s karbidopom uz preporučenu shemu doziranja (200 mg entakapona do 10 puta na dan).
English: Patients receiving less than 70-100 mg carbidopa a day are more likely to experience nausea and vomiting.
Croatian: U bolesnika koji dnevno primaju manje od 70-100 mg karbidope postoji veća mogućnost za pojavu mučnine i povraćanja.
English: Entacapone showed little or no inhibition of other types of P450 isoenzymes (CYP1A2, CYP2A6, CYP2D6, CYP2E1, CYP3A and CYP2C19); see section 4.5.
Croatian: Entakapon je pokazao malo ili nikakvo inhibiranje drugih tipova P450 izoenzima (CYP1A2, CYP2A6, CYP2D6, CYP2E1, CYP3A i CYP2C19); vidjeti dio 4.5.
English: Entacapone in high doses may affect the absorption of carbidopa.
Croatian: Entakapon u visokim dozama može utjecati na apsorpciju karbidope.
English: Entacapone is almost completely metabolized prior to excretion via urine (10 to 20%) and bile/faeces (80 to 90%).
Croatian: Entakapon se gotovo u potpunosti metabolizira prije izlučivanja mokraćom (10 do 20%) i žuči/stolicom (80 do 90%).
English: The SmPC section 4.4 and 4.8 are being updated to add Dopamine Dysregulation Syndrome (DDS) with a frequency “not known” and to add further explanation with regards to DDS to section 4.8 to increase awareness and understanding on the pathology and add a warning to section 4.4 to recommend relevant precautions.
Croatian: Dijelovi 4.4 i 4.8 sažetka opisa svojstava lijeka se ažuriraju kako bi se dodao sindrom poremećene regulacije dopamina (DDS) s učestalošću "nepoznato" i kako bi se dodalo dodatno objašnjenje u vezi s DDS-om u dijelu 4.8 kako bi se povećala svijest i razumijevanje patologije te dodalo upozorenje u dijelu 4.4 kojim se preporučuju odgovarajuće mjere opreza.
English: Therefore, any abrupt dose reduction or withdrawal of levodopa should be carefully observed, particularly in patients who are also receiving neuroleptics.
Croatian: Stoga treba pažljivo promatrati svako naglo smanjenje doze ili prekid uzimanja levodope, posebno u bolesnika koji uzimaju i neuroleptike.
English: The post-marketing data includes isolated cases of overdose in which the reported highest daily doses of levodopa and entacapone have been at least 10,000 mg and 40,000 mg, respectively.
Croatian: Podaci nakon stavljanja lijeka u promet uključuju izolirane slučajeve predoziranja, u kojima su najviše prijavljene dnevne doze levodope i entakapona bile najmanje 10 000 mg, odnosno 40 000 mg.
English: Carbidopa is absorbed and eliminated slightly slower compared with levodopa.
Croatian: Karbidopa se apsorbira i eliminira nešto sporije u usporedbi s levodopom.
English: HDPE bottle with a child resistant PP-closure.
Croatian: HDPE bočica s polipropilenskim sigurnosnim zatvaračem za djecu.
English: Label Orion Corporation
Croatian: Naljepnica Orion Corporation
English: **The incidence rates of myocardial infarction and other ischemic heart disease events (0.43% and 1.54%, respectively) are derived from an analysis of 13 double-blind studies involving 2082 patients with end-of-dose motor fluctuations receiving entacapone.
Croatian: **Stope incidencije infarkta miokarda i drugih događaja vezanih uz ishemičku srčanu bolest (0,43%, odnosno 1,54%) su izvedene iz analize 13 dvostruko slijepih ispitivanja u kojima su bila uključena 2082 bolesnika s motoričkim fluktuacijama na kraju intervala doziranja koji su primali entakapon.
English: The use of glucose oxidase methods may give false negative results for glycosuria.
Croatian: Primjena metoda s glukoza-oksidazom može dati lažno negativne rezultate za glikozuriju.