FrancophonIA/ELRC3.0 huggingface dataset:
English: Bleeding gums, weight gain, severe chest pain (angina pectoris), heart muscle disease, (signs include fatigue, chest pain and palpitations), enlarged heart, accumulation of fluid around the heart, loss of coordination, difficulty in speaking, dry skin, migraine, visual disturbances or double vision, ringing in the ears, dizziness on standing up (especially when getting up from a sitting or lying position), increased need to pass water at night, pain, ‘flu-like' symptoms, sleepiness, widening of blood vessels, inflammation of the large bowel (signs include: diarrhoea, usually with blood and mucus, stomach pain, fever), inflammation of the stomach (signs include: pain, nausea, vomiting), area of abnormal density in the lung, increased creatinine level in blood tests, which may be a sign of kidney problems.
Slovenian: Redki neželeni učinki: pojavijo se pri največ 1 od 1.000 bolnikov krvavenje dlesni, pridobitev telesne mase, močna bolečina v prsih (angina pektoris), obolenje srčne mišice (znaki vključujejo utrujenost, bolečino v prsih in palpitacije), zvečanje srca, kopičenje tekočine okrog srca, izguba koordinacije, težave z govorom, suha koža, migrenski glavobol, poslabšanje vida ali dvojni vid, zvonjenje v ušesih, omedlevica v pokončnem položaju (posebno pri vstajanju iz sedečega ali ležečega položaja), povečana potreba po odvajanju vode ponoči, bolečine, gripi podobni simptomi, zaspanost, razširitev krvnih žil, vnetje debelega črevesa (znaki vključujejo: drisko, navadno s krvjo in sluzjo, bolečine v trebuhu, vročino), vnetje želodca (znaki vključujejo: bolečino, navzeo, bruhanje), predel nenormalne gostote v pljučih, zvečana koncentracija kreatinina pri krvnih preiskavah, ki je lahko znak težav z ledvicami.
English: Anagrelide at ≥60 mg/kg increased parturition time and mortality in the dam and foetus respectively.
Slovenian: Anagrelid je v odmerkih ≥60 mg/kg podaljšal porod pri podganji samici in zvečal smrtnost pri plodu.
English: Xagrid 0.5 mg hard capsules anagrelide
Slovenian: IME ZDRAVILA Xagrid 0,5 mg trde kapsule anagrelid
English: At the NOEL dose (30mg/kg/day), the AUCs for anagrelide and the metabolites BCH24426 and RL603 were 425-, 31- and 13-fold higher than the AUC in humans administered an oral dose of anagrelide 2 mg/day, respectively.
Slovenian: Pri odmerku NOEL (30 mg/kg/dan) so bile AUC za anagrelid oziroma presnovke BCH24426 in RL603 425-, 31- oziroma 13-krat večje kot AUC pri ljudeh, ki so prejemali peroralni odmerek anagrelida 2 mg/dan.
English: Xagrid contains the active substance, anagrelide.
Slovenian: Zdravilo Xagrid vsebuje učinkovino anagrelid.
English: Xagrid should not be taken while breast-feeding.
Slovenian: Zdravila Xagrid v času dojenja ne smete jemati.
English: Talk to your doctor before taking Xagrid:
Slovenian: Opozorila in previdnostni ukrepi Pred začetkom jemanja zdravila Xagrid se posvetujte z zdravnikom:
English: A feeling of weakness or feeling unwell, high blood pressure, irregular heart beat, fainting, chills or fever, indigestion, loss of appetite, constipation, bruising, bleeding, swelling (oedema), weight loss, muscle aches, painful joints, back pain, decreased or loss of feeling or sensation such as numbness, especially in the skin, abnormal feeling or sensation such as tingling and ‘pins and needles', sleeplessness, depression, confusion, nervousness, dry mouth, loss of memory, breathlessness, nosebleed, serious lung infection with fever, shortness of breath, cough, phlegm; hair loss, skin itching or discolouration, impotence, chest pain, reduction in blood platelets, which increases the risk of bleeding or bruising (thrombocytopenia), accumulation of fluid around the lungs or an increase in liver enzymes.
Slovenian: zbadanje in mravljinčenje, nespečnost, depresija, zmedenost, nervoza, suha usta, izguba spomina, zasoplost, krvavenje iz nosa, resna okužba pljuč z vročino, kratko sapo, kašljem, gnojnim izkašljevanjem, izpadanje las, srbenje ali razbarvanje kože, impotenca, bolečina v prsih, zmanjšanje koncentracije krvnih ploščic, ki zveča tveganje krvavitev ali podplutb (trombocitopenija), kopičenje tekočine okrog pljuč ali zvišanje jetrnih encimov.
English: Xagrid contains lactose
Slovenian: Zdravilo Xagrid vsebuje laktozo
English: One hard capsule contains 0.5 mg anagrelide (as anagrelide hydrochloride).
Slovenian: Ena kapsula vsebuje 0,5 mg anagrelida (v obliki anagrelidijevega klorida).
English: At the NOEL dose (3mg/kg/day), the AUCs for anagrelide and the metabolites BCH24426 and RL603 were 14, 2 and 2-fold higher than the AUC in humans administered an oral dose of anagrelide 2mg/day.
Slovenian: Pri odmerku NOEL (3 mg/kg/dan) so bile AUC za anagrelid oziroma presnovka RL603 in BCH24426 14-, 2- oziroma 2krat večje kot AUC pri ljudeh, ki so jim dajali peroralni odmerek anagrelida 2 mg/dan.
English: • Medicines that can alter your heart rhythm e.g. sotalol, amiodarone;
Slovenian: • zdravila, ki lahko vplivajo na srčni ritem, n.pr.
English: Nervous system disorders
Slovenian: Motnje v delovanju jeter
English: Xagrid contains lactose.
Slovenian: Zdravilo Xagrid vsebuje laktozo.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING AND THE IMMEDIATE PACKAGING
Slovenian: PODATKI NA ZUNANJI OVOJNINI IN PRIMARNI OVOJNINI ZUNANJA OVOJNINA IN NALEPKA NA PLASTENKI
English: Tinnitus
Slovenian: kondoma).
English: How to store Xagrid
Slovenian: Shranjevanje zdravila Xagrid
English: The potential risks and benefits of anagrelide therapy in a patient with mild impairment of hepatic function should be assessed before treatment is commenced (see sections 4.3 and 4.4).
Slovenian: Pred začetkom zdravljenja je treba ugotoviti morebitna tveganja in koristi ob zdravljenju z anagrelidom pri bolnikih z blagim do hudim poslabšanim delovanjem jeter (glejte poglavji 4.3 in 4.4).
English: PHARMACEUTICAL FORM AND CONTENTS
Slovenian: FARMACEVTSKA OBLIKA IN VSEBINA 100 trdih kapsul
English: Hepatic impairment
Slovenian: Oslabljena jetra
English: The effects of medicinal products with similar properties such as the inotropes milrinone, enoximone, amrinone, olprinone and cilostazol may be exacerbated by anagrelide.
Slovenian: • Anagrelid je zaviralec PDE III. Anagrelid utegne poslabšati učinke zdravil s podobnimi lastnostmi, kot so inotropna zdravila milrinon, enoksimon, amrinon, olprinon in cilostazol.
English: Symptoms resolved with conservative management.
Slovenian: Simptomi prevelikega odmerka so sinusna tahikardija in bruhanje, ki pa jih odpravimo s konzervativnim zdravljenjem.
English: Dizziness, tiredness, rapid heart beat, irregular or strong heartbeat (palpitations), feeling sick (nausea), diarrhoea, stomach pain, wind, being sick (vomiting), reduction in red blood cell count (anaemia), fluid retention or rash.
Slovenian: Pogosti neželeni učinki: pojavijo se pri največ 1 od 10 bolnikov vrtoglavica, utrujenost, pospešen srčni utrip, nereden ali močan srčni utrip (palpitacije), siljenje na bruhanje (navzea), driska, bolečine v trebuhu, vetrovi, bruhanje, zmanjšanje števila rdečih krvničk (anemija), zastajanje tekočine ali izpuščaji.
English: Contents of the pack and other information What Xagrid contains
Slovenian: Shranjevanje zdravila Xagrid Vsebina pakiranja in dodatne informacije
English: The potential risks and benefits of anagrelide therapy in a patient with mild impairment of hepatic function should be assessed before treatment is commenced.
Slovenian: Pred začetkom zdravljenja je treba ugotoviti morebitno tveganje in koristi ob zdravljenju z anagrelidom pri bolnikih z blagim ali zmernim poslabšanjem delovanja jeter.
English: Renal impairment
Slovenian: Oslabljene ledvice
English: Gastrointestinal haemorrhage Pancreatitis Anorexia Dyspepsia Constipation
Slovenian: Bolezni prebavil driska bruhanje bolečine v trebuhu slabost vetrovi gastrointestinalna krvavitev vnetje trebušne slinavke anoreksija prebavne motnje zaprtje gastrointestinalne motnje kolitis gastritis krvavitev dlesni
English: Tubulointerstitial nephritis
Slovenian: Bolezni sečil impotenca ledvična odpoved nokturija tubulointersticijski nefritis
English: Skin and subcutaneous tissue disorders
Slovenian: Bolezni kože in podkožja izpuščaji izpadanje las pruritus razbarvanje kože suha koža
English: Skin discoloration
Slovenian: Krvne ploščice
English: Gastrointestinal disorder
Slovenian: Motnje v delovanju ledvic
English: Musculoskeletal and connective tissue disorders
Slovenian: Bolezni mišičnoskeletnega sistema in vezivnega tkiva artralgija mialgija bolečine v križu
English: Breast-feeding
Slovenian: klopidogrel;
English: Shire Pharmaceuticals Ireland Limited Dublin 2
Slovenian: IME IN NASLOV IMETNIKA DOVOLJENJA ZA PROMET Z ZDRAVILOM Shire Pharmaceuticals Ireland Ltd.
English: Take your next dose at the usual time.
Slovenian: Naslednji odmerek vzemite ob običajnem času.
English: Your doctor will take further measures.
Slovenian: Nadaljnje ukrepe bo uvedel zdravnik.
English: Diameter: about 8 mm.
Slovenian: Premer: približno 8 mm.
English: Its duration of action is 24 hours - also depending on dose.
Slovenian: Trajanje njegovega delovanja je 24 ur, kar je odvisno tudi od odmerka.
English: The overall design of the study was adequately pre-specified in the protocol and was considered acceptable.
Slovenian: Celotna zasnova študije je bilo ustrezno predhodno opredeljena v protokolu in je bila sprejemljiva.
English: Infections are more likely.
Slovenian: Verjetnejše so okužbe.
English: These effects are usually reversible.
Slovenian: Ti učinki so navadno reverzibilni.
English: Alcohol enhances the hypotensive effect.
Slovenian: Alkohol poveča hipotenzivni učinek.
English: Caution is required with concomitant use.
Slovenian: Pri sočasni uporabi je potrebna previdnost.
English: • Heart failure after acute myocardial infarction (during the first 28 days).
Slovenian: • Srčna odpoved po akutnem miokardnem infarktu (v prvih 28 dneh).
English: Lisonorm may influence the ability to drive and operate machines (particularly during the initial period of treatment).
Slovenian: Zdravilo Lisonorm lahko vpliva na sposobnost vožnje in upravljanja s stroji (predvsem v začetnem obdobju zdravljenja).
English: The maximum daily dose is one tablet.
Slovenian: Največji dnevni odmerek je ena tableta.
English: Do not take a double dose to make up for a forgotten tablet, to avoid the risk of overdose.
Slovenian: Ne vzemite dvojnega odmerka, če ste pozabili vzeti prejšnjo tableto, da se izognete tveganju prevelikega odmerjanja.
English: LC-MS/MS methods were validated for analysis of both compounds, and the stability of the samples was documented over the period of sample storage.
Slovenian: Metode LC-MS/MS so bile potrjene za analizo obeh sestavin, stabilnost vzorcev pa je bila dokumentirana v obdobju shranjevanja vzorcev.
English: Additionally, there was a high incidence of QT prolongation observed in 16.7% subjects (n=8).
Slovenian: Poleg tega je bila opažena tudi visoka pojavnost podaljšanega intervala QT, ki se je pojavil pri 16,7 % sodelujočih (n=8).
English: Some of these patients developed serious infections, which in a few instances did not respond to intensive antibiotic therapy.
Slovenian: Pri nekaterih od teh bolnikov so se razvile resne okužbe, ki se v nekaterih primerih niso odzvale na intenzivno zdravljenje z antibiotiki.
English: Due to the slow onset of action, acute hypotension does not occur.
Slovenian: Zaradi počasnega začetka delovanja se akutna hipotenzija ne pojavi.
English: The sampling interval and wash-out period were considered long enough and the statistical evaluation was also appropriate.
Slovenian: Interval vzorčenja in obdobje izpiranja sta bila dovolj dolga, pa tudi statistična ocena je bila ustrezna.
English: The bioavailability of amlodipine is 64 to 80 %; its volume of distribution is approximately 20 l/kg.
Slovenian: Biološka uporabnost amlodipina je od 64- do 80-odstotna; njegov volumen porazdelitve je približno 20 l/kg.
English: The effective half-life of lisinopril is 12.6 hours.
Slovenian: Učinkoviti razpolovni čas lizinoprila je 12,6 ure.
English: This phenomenon appeared to be more likely to occur during the first weeks of combined treatment and in patients with renal impairment.
Slovenian: Ta pojav je verjetnejši v prvih tednih kombiniranega zdravljenja in pri bolnikih z ledvično okvaro.
English: Dose reduction and/or discontinuation of the diuretic may also be required.
Slovenian: Morda bo potrebno tudi zmanjšanje odmerka in/ali prekinitev uporabe diuretika.
English: OVERALL SUMMARY OF THE SCIENTIFIC EVALUATION OF LISONORM AND ASSOCIATED NAMES (SEE ANNEX I)
Slovenian: SPLOŠNI POVZETEK ZNANSTVENEGA VREDNOTENJA ZDRAVILA LISONORM IN Z NJIM POVEZANIH IMEN (GLEJTE DODATEK I)
English: It reduces peripheral vascular resistance and systemic blood pressure.
Slovenian: Zmanjša periferni vaskularni upor in sistemski krvni tlak.
English: In the systemic circulation 95 to 98 % of amlodipine is bound to plasma protein.
Slovenian: V sistemskem obtoku se 95 do 98 % amlodipina veže na beljakovine v plazmi.
English: If hypotension occurs, probably as a consequence of this mechanism, it can be corrected by volume expansion
Slovenian: Če se pojavi hipotenzija, ki je verjetno posledica tega mehanizma, se lahko popravi s zvečanjem prostornine.
English: Since no dose recommendations have been established, this medicinal product should therefore be administered with caution, weighing individually the expected benefits and potential risks of the treatment.
Slovenian: Ker priporočil za odmerjanje ni, je treba to zdravilo previdno uporabljati, pri čemer je treba pretehtati pričakovane koristi in morebitna tveganja zdravljenja.
English: Taking Lisonorm with food and drink Lisonorm can be taken with or without food, but alcohol should be avoided during treatment.
Slovenian: Jemanje zdravila Lisonorm skupaj s hrano in pijačo Zdravilo Lisonorm se lahko jemlje s hrano ali brez nje, alkoholu pa se je treba med zdravljenjem izogibati.
English: • Unstable angina pectoris (excluding Prinzmetal's angina).
Slovenian: • Nestabilna angina pektoris (razen Prinzmetalove angine).
English: Sympathomimetics may reduce the antihypertensive effects of ACE inhibitors; patients should be carefully monitored to confirm that the desired effect is being obtained.
Slovenian: Simpatikomimetiki lahko zmanjšajo anhihipertenzivne učinke zaviralcev ACE; bolnike je treba skrbno spremljati, da potrdite, ali se je dosegel želeni učinek.
English: Frequencies are defined as follows: Very common (≥ 1/10), Common (≥ 1/100 to < 1/10), Uncommon (≥ 1/1,000 to < 1/100), Rare (≥ 1/10,000 to <1/1,000), Very rare (< 1/10,000), not known (cannot be estimated from the available data).
Slovenian: Njihova pogostnost je opredeljena na naslednji način: zelo pogosti (> 1/10), pogosti (> 1/100 do < 1/10), občasni (> 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
English: Special caution is necessary when Lisonorm is taken together with the following medicines:
Slovenian: Posebno je treba biti previden, kadar se zdravilo Lisonorm jemlje skupaj z naslednjimi zdravili:
English: You might not have any symptoms from your too high blood pressure, but it may increase the risk of certain complications (such as stroke or heart attack), if you do not take your antihypertensive medicine regularly.
Slovenian: Morda zaradi previsokega krvnega tlaka nimate nobenih simptomov, vendar pa lahko poveča tveganje nekaterih zapletov (kot je možganska kap ali srčni napad), če zdravil proti hipertenziji ne jemljete redno.
English: If Lisonorm is used in such patients, periodic monitoring of white blood cell counts is advised and patients should be instructed to report any sign of infection.
Slovenian: Če se zdravilo Lisonorm uporablja pri teh bolnikih, se priporoča periodično spremljanje števila belih krvnih celic, bolnikom pa je treba svetovati, naj zdravnika obvestijo o vsakršnih znakih okužbe.
English: • narcotics, morphine and related drugs used to treat severe pain
Slovenian: • narkotiki, morfin in sorodna zdravila, ki se uporabljajo za zdravljenje hude bolečine,
English: Frequencies are defined as follows: very common: affects more than 1 user in 10 common: affects 1 to 10 users in 100 uncommon: affects 1 to 10 users in 1,000 rare: affects 1 to 10 users in 10,000 very rare: affects less than 1 user in 10,000 not known: frequency cannot be estimated from the available data.
Slovenian: Njihova pogostnost je opredeljena na naslednji način: zelo pogosti: prizadenejo več kot 1 od 10 uporabnikov, pogosti: prizadenejo 1 do 10 od 100 uporabnikov, občasni: prizadenejo 1 do 10 od 1.000 uporabnikov, redki: prizadenejo 1 do 10 od 10.000 uporabnikov, zelo redki: prizadenejo manj kot 1 od 10.000 uporabnikov, neznana: na podlagi razpoložljivih podatkov ni mogoče oceniti pogostosti.
English: Elimination from the plasma is biphasic with a terminal elimination half-life of about 30-50 hours.
Slovenian: Izločanje iz plazme je dvofazno, pri čemer je končni razpolovni čas izločanja približno 30-50 ur.
English: ANNEX I LIST OF THE NAMES, PHARMACEUTICAL FORM, STRENGTH OF THE MEDICINAL PRODUCT, ROUTE OF ADMINISTRATION, APPLICANTS / MARKETING AUTHORISATION HOLDERS IN THE MEMBER STATES
Slovenian: DODATEK I SEZNAM IMEN, FARMACEVTSKIH OBLIK, JAKOSTI ZDRAVILA, POTI UPORABE ZDRAVILA, PREDLAGATELJEV, IMETNIKOV DOVOLJENJA ZA PROMET Z ZDRAVILOM V DRŽAVAH ČLANICAH
English: WHAT LISONORM IS AND WHAT IT IS USED FOR
Slovenian: KAJ JE ZDRAVILO LISONORM IN ZA KAJ GA UPORABLJAMO
English: The appearance of QT prolongation was similar in all 3 different treatment options, and there were no statistically significant differences between predose and post-dose QTc values.
Slovenian: Pojav podaljšanega intervala QT je bil podoben pri uporabi vseh treh možnostih zdravljenja, prav tako pa ni bilo statistično bistvenih razlik v vrednosti podaljšanega intervala QTc pred in po zaužitju odmerka.
English: Since food does not affect absorption, Lisonorm may be taken irrespective of meals.
Slovenian: Ker hrana ne vpliva na absorpcijo, se lahko zdravilo Lisonorm jemlje ne glede na obroke.
English: No experience is available with the use of Lisonorm in pregnant women from adequately controlled clinical studies.
Slovenian: Pri nosečnicah ni izkušenj z uporabo zdravila Lisonorm iz ustrezno nadzorovanih kliničnih študij.
English: If available, treatment with angiotensin II infusion may also be considered.
Slovenian: Če je na razpolago, lahko razmislite tudi o zdravljenju z infundiranjem angiotenzina II.
English: • Haemodynamically significant obstruction in the outflow tract of the left ventricle (aortic stenosis,
Slovenian: • Hemodinamično pomembna obstrukcija izhodnega trakta levega prekata (aortna stenoza,
English: It is not known whether amlodipine is excreted in human milk.
Slovenian: Ni znano, ali se amlodipin izloča v materino mleko.
English: Since amlodipine is slowly absorbed, gastric lavage can be useful in some cases.
Slovenian: Ker se amlodipin absorbira počasi, je lahko v nekaterih primerih koristna gastrična lavaža.
English: These patients presented with abdominal pain (with or without nausea and vomiting); in some cases there was no prior facial angioedema and C-1 esterase levels were normal.
Slovenian: Ti bolniki so imeli abdominalno bolečino (s slabostjo in bruhanjem ali brez njiju); v nekaterih primerih predhodni angioedem obraza ni bil prisoten, raven esteraze C1 pa je bila normalna.
English: Fixed dose combination
Slovenian: Fiksna kombinacija
English: In patients with normal renal function and no other complicating factors, neutropenia occurs rarely.
Slovenian: Pri bolnikih z normalnim delovanjem ledvic in brez drugih dejavnikov za zaplete je nevtropenija redka.
English: • other medicines used to lower blood pressure (antihypertensives)
Slovenian: • druga zdravila za zniževanje krvnega tlaka (antihipertenzivi),
English: The most common adverse reactions with the combination were headache (8%), cough (5%), and dizziness (3%).
Slovenian: Najpogostejši neželeni učinki pri tej kombinaciji so bili glavobol (8 %), kašelj (5 %) in omotica (3 %).
English: Rarely, acute renal failure may occur, especially in patients with compromised renal function such as the elderly or dehydrated.
Slovenian: Redko se lahko pojavi akutna ledvična odpoved, zlasti pri bolnikih z okvarjenim delovanjem ledvic, kot so starejši ali dehidrirani bolniki.
English: Amlodipine, used at similar doses in elderly or younger patients, is equally well tolerated and therefore, normal dose is recommended for older people.
Slovenian: Amlodipin, ki se pri starejših in mlajših bolnikih uporablja v podobnih odmerkih, se enako dobro prenaša, zato se pri starejših osebah priporoča normalen odmerek.
English: This is especially likely in patients with renal insufficiency.
Slovenian: To je še posebno verjetno pri bolnikih z ledvično insuficienco.
English: These changes may be accompanied by an increase in cardiac output at unchanged heart frequency, as well as an increase in renal blood flow.
Slovenian: Te spremembe lahko spremljata povečanje srčnega iztisa pri nespremenjeni srčni frekvenci in povečanje ledvičnega krvnega pretoka.
English: Steady-state plasma levels are reached after 7 to 8 days of consecutive daily dosing.
Slovenian: Stanje dinamičnega ravnovesja v plazmi se doseže po sedmih do osmih dneh neprekinjenega dnevnega odmerjanja.
English: Amlodipine (n=64)
Slovenian: Amlodipin (n = 64)
English: Peak plasma concentration (Cmax) occurs 6 to 10 hours after dosing.
Slovenian: Največja koncentracija v plazmi (Cmax) se pojavi šest do deset ur po odmerjanju.
English: Lisonorm is used to treat hypertension (high blood pressure).
Slovenian: Zdravilo Lisonorm se uporablja za zdravljenje hipertenzije (visokega krvnega tlaka).
English: INFORMATION IN BRAILLE Lisonorm 10/5 mg
Slovenian: PODATKI V BRAILLOVI PISAVI Lisonorm 10/5 mg
English: Concomitant use with glyceryl trinitrate and other nitrates, or other vasodilators, may further reduce blood pressure.
Slovenian: Sočasna uporaba z gliceriltrinitratom in drugimi nitrati ali drugimi vazodilatatorji lahko dodatno zniža krvni tlak.
English: If you have the impression that the effect of Lisonorm is too strong or too weak, talk to your doctor or pharmacist.
Slovenian: Če menite, da je učinek zdravila Lisonorm premočan ali prešibak, se posvetujte z zdravnikom ali farmacevtom.
English: Compensatory activation of the renin-angiotensin-aldosterone system (RAAS) should be expected and therefore, counter-regulatory mechanisms activated by ACE inhibitors may contribute to the restoration of physiological responses to increased salt intake.
Slovenian: Pričakuje se kompenzacijska aktivacija sistema renin-angiotenzin-aldosteron, zato lahko nasprotno regulacijski mehanizmi, ki jih aktivirajo zaviralci ACE, prispevajo k obnovitvi fizioloških odzivov na povečan vnos soli.
English: • insulin and oral antidiabetics
Slovenian: • insulin in peroralni antidiabetiki,
English: If concomitant use of the abovementioned substances is needed, regular monitoring of potassium serum levels is recommended (see section 4.5).
Slovenian: Če je potrebna sočasna uporaba zgoraj naštetih snovi, se priporoča redno spremljanje ravni kalija v serumu (glejte poglavje 4.5).
English: This may result in prolonged bleeding, tiredness, weakness, disease of the lymph node, autoimmune disease (in which the body attacks itself).
Slovenian: To lahko povzroči dolgotrajno krvavitev, utrujenost, šibkost, bolezen bezgavk, avtoimunsko bolezen (pri kateri telo napade samo sebe).
English: The antihypertensive efficacy of lisinopril is also maintained on the long term.
Slovenian: Antihipertenzivna učinkovitost lizinoprila se vzdržuje tudi dolgotrajno.
English: Although some dihydropyridine compounds have been found to be teratogenic in animals, data in the rat and rabbit for amlodipine provide no evidence for a teratogenic effect (see section 5.3).
Slovenian: Čeprav so ugotovili, da so nekatere dihidropiridinske spojine teratogene pri živalih, podatki pri podganah in zajcih ne kažejo nikakršnih dokazov o teratogenih učinkih amlodipina (glejte poglavje 5.3).