FrancophonIA/ELRC3.0 huggingface dataset:
English: You must take at least 5 doses during the seven days before the first dose of Pemetrexed Krka.
Croatian: Morate uzeti barem 5 doza tijekom 7 dana prije prve doze lijeka Pemetrexed Krka.
English: White to either light yellow or green yellow lyophilized cake or powder.
Croatian: Bijeli do svijetložuti ili zeleno-žuti liofilizirani kolačić ili prašak.
English: You will also receive an injection of vitamin B12 (1000 micrograms) in the week before administration of Pemetrexed Krka and then approximately every 9 weeks (corresponding to 3 courses of Pemetrexed Krka treatment).
Croatian: Također ćete dobiti injekciju vitamina B12 (1000 mikrograma) u tjednu prije primjene lijeka Pemetrexed Krka i zatim otprilike svakih 9 tjedana (što odgovara 3 ciklusa liječenja lijekom Pemetrexed Krka).
English: - Immune mediated haemolytic anaemia (antibody-mediated destruction of red blood cells) - Hepatitis (inflammation of the liver) - Anaphylactic shock (severe allergic reaction)
Croatian: - imunološki posredovana hemolitička anemija (razaranje crvenih krvnih stanica posredstvom protutijela) - hepatitis (upala jetre) - anafilaktički šok (teška alergijska reakcija)
English: ** which is derived from the term “renal/genitourinary other”.
Croatian: ** Izveden iz izraza „ostali bubrežni/genitourinarni poremećaji“.
English: Before each infusion you will have samples of your blood taken to evaluate if you have sufficient kidney and liver function and to check that you have enough blood cells to receive Pemetrexed Krka.
Croatian: Prije svake infuzije uzet će Vam se uzorak krvi kako bi se provjerilo jesu li Vam bubrežna ili jetrena funkcija dovoljno dobre i imate li dovoljno krvnih stanica da biste primili lijek Pemetrexed Krka.
English: *p-values < 0.05 comparing pemetrexed/cisplatin to gemcitabine/cisplatin, using Fisher Exact test.
Croatian: * P-vrijednosti < 0,05 za usporedbu kombinacija pemetreksed/cisplatin i gemcitabin/cisplatin uz primjenu Fisherova egzaktnog testa.
English: The use of Pemetrexed Krka should be avoided during pregnancy.
Croatian: Primjena lijeka Pemetrexed Krka mora se izbjegavati tijekom trudnoće.
English: If you currently have or have previously had problems with your kidneys, talk to your doctor or hospital pharmacist as you may not be able to receive Pemetrexed Krka.
Croatian: Ako trenutno imate ili ste prethodno imali problema s bubrezima, obratite se svom liječniku ili bolničkom ljekarniku jer možda nećete smjeti primati lijek Pemetrexed Krka.
English: The dose of Pemetrexed Krka is 500 milligrams for every square metre of your body's surface area.
Croatian: Doza lijeka Pemetrexed Krka je 500 miligrama po svakom kvadratnom metru Vaše površine tijela.
English: Chemical and physical in-use stability of reconstituted and infusion solutions of pemetrexed were demonstrated for 24 hours at 2°C to 8°C (and 25°C).
Croatian: Dokazano je da su rekonstituirana otopina pemetrekseda i otopina pemetrekseda za infuziju fizikalno i kemijski stabilne tijekom 24 sata ako se čuvaju na temperaturi od 2°C do 8°C (i 25°C).
English: Pemetrexed Placebo
Croatian: - Pemetreksed - Placebo
English: What you need to know before you use Pemetrexed Krka
Croatian: Što morate znati prije nego počnete uzimati Pemetrexed Krka
English: Intravenous use after reconstitution and dilution.
Croatian: Intravenski nakon pripreme otopine i razrjeđivanja.
English: 3 and platelets should be ≥ 100,000 cells/mm Creatinine clearance should be ≥ 45 ml/min.
Croatian: ≥ 100 000 stanica/mm Klirens kreatinina mora biti  45 ml/min.
English: Do not use this medicine after the expiry date which is stated on the label and carton after EXP.
Croatian: Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju iza oznake EXP.
English: The doctor or hospital pharmacist will work out the dose you need based on your height and weight.
Croatian: Liječnik ili bolnički ljekarnik će odrediti potrebnu dozu na temelju
English: ***Integrated adverse reactions table combines the results of the JMEN pemetrexed maintenance (N=663) and PARAMOUNT continuation pemetrexed maintenance (N=539) studies.
Croatian: *** Integrirana tablica nuspojava objedinjuje rezultate ispitivanja terapije održavanja pemetreksedom (JMEN) (N=663) i kontinuirane terapije održavanja pemetreksedom (PARAMOUNT) (N=539).
English: a Grade
Croatian: a stupanj
English: Children and adolescents There is no relevant use of Pemetrexed Krka in the paediatric population
Croatian: Djeca i adolescenti Pemetrexed Krka nema relevantne primjene u pedijatrijskoj populaciji.
English: Pemetrexed Krka is a medicine used in the treatment of cancer.
Croatian: Pemetrexed Krka je lijek koji se koristi za liječenje raka.
English: Pemetrexed Krka can be prescribed to you if you have lung cancer at an advanced stage if your disease has responded to treatment or it remains largely unchanged after initial chemotherapy.
Croatian: Pemetrexed Krka Vam se može propisati ako imate rak pluća u uznapredovaloj fazi i ako je Vaša bolest reagirala na liječenje ili ostala uglavnom nepromijenjena nakon početne kemoterapije.
English: If you have an accumulation of fluid around your lungs, your doctor may decide to remove the fluid before giving you Pemetrexed Krka.
Croatian: Ako Vam se oko pluća nakupila tekućina, liječnik može odlučiti ukloniti tu tekućinu prije primjene lijeka Pemetrexed Krka.
English: You must continue taking the folic acid for 21 days after the last dose of Pemetrexed Krka.
Croatian: Morate nastaviti uzimati folatnu kiselinu još najmanje 21 dan nakon posljednje doze lijeka Pemetrexed Krka.
English: Dose for cisplatin (mg/m
Croatian: Doza cisplatina (mg/m
English: Your doctor will use this body surface area to work out the right dose for you.
Croatian: Vašeg tijela odrediti odgovarajuću dozu za Vas.
English: Corticosteriods: your doctor will prescribe you steroid tablets (equivalent to 4 milligram of dexamethasone twice a day) that you will need to take on the day before, on the day of, and the day after Pemetrexed Krka treatment.
Croatian: Kortikosteroidi: liječnik će Vam propisati tablete kortikosteroida (ekvivalentne dozi deksametazona od 4 mg dvaput na dan) koje ćete morati uzeti dan prije, na sam dan i dan nakon primjene lijeka Pemetrexed Krka.
English: Alkaline phosphatase, AST and ALT ≤ 5-times upper limit of normal is acceptable if liver has tumour involvement.
Croatian: Prihvatljive su vrijednosti alkalne fosfataze, AST-a i ALT-a od  5 puta iznad gornje granice normale ako je jetra zahvaćena tumorom.
English: After reconstitution (see section 6.6), each vial contains 25 mg/ml pemetrexed.
Croatian: Nakon rekonstitucije (vidjeti dio 6.6), jedna bočica sadrži 25 mg/ml pemetrekseda.
English: If you have been recently vaccinated, please tell your doctor, as this can possibly cause bad effects with Pemetrexed Krka.
Croatian: Ako ste nedavno cijepljeni, obavijestite o tome svog liječnika jer to može izazvati štetne učinke uz primjenu lijeka Pemetrexed Krka.
English: Treatment with Pemetrexed Krka should be discontinued if a patient experiences any haematologic or non-haematologic Grade 3 or 4 toxicity after 2 dose reductions or immediately if Grade 3 or 4 neurotoxicity is observed.
Croatian: Liječenje lijekom Pemetrexed Krka se mora obustaviti ako se u bolesnika pojavi bilo kakva hematološka ili nehematološka toksičnost stupnja 3 ili 4 nakon dvaju sniženja doze, odnosno odmah ako se ustanovi neurotoksičnost stupnja 3 ili 4.
English: * Refer to National Cancer Institute CTC version 2 for each grade of toxicity except the term “creatinine clearance decreased”
Croatian: * Za sve stupnjeve toksičnosti vidjeti CTC NCI verziju 2, osim za izraz „smanjen klirens kreatinina“
English: Before the start of any cycle of chemotherapy, patients are required to have the following: absolute neutrophil count (ANC) should be ≥ 1500 cells/mm
Croatian: Prije početka svakog ciklusa kemoterapije bolesnici moraju imate sljedeće vrijednosti laboratorijskih parametara: apsolutni broj neutrofila (ABN) mora biti ≥ 1500 stanica/mm
English: National Cancer Institute Common Toxicity Criteria (CTC v2.0; NCI 1998)
Croatian: Zajednički kriteriji toksičnosti Nacionalnog instituta za rak (CTC v2.0; NCI 1998)
English: All grades toxicit y (%)
Croatian: Svi stupnjevi toksičnost i(%)
English: Women must use effective contraception during treatment with Pemetrexed Krka.
Croatian: Žene moraju primjenjivati djelotvornu kontracepciju tijekom liječenja lijekom Pemetrexed Krka.
English: - If you experience sudden breathlessness, intense chest pain or cough with bloody sputum (uncommon) (may indicate a blood clot in the blood vessels of the lungs).
Croatian: - ako iskusite iznenadni nedostatak zraka, osjećate intenzivnu bol u prsima ili iskašljavate krv (manje često) (može ukazivati na krvni ugrušak u krvnim žilama u plućima).
English: Driving and using machines Pemetrexed Krka may make you feel tired.
Croatian: Upravljanje vozilima i strojevima Pemetrexed Krka može izazvati umor.
English: Calculate the dose and the number of Pemetrexed Krka vials needed.
Croatian: Izračunajte dozu i potreban broj bočica lijeka Pemetrexed Krka.
English: Vitamin supplementation: your doctor will prescribe you oral folic acid (vitamin) or a multivitamin containing folic acid (350 to 1000 micrograms) that you must take once a day while you are taking Pemetrexed Krka.
Croatian: Vitaminska nadoknada: liječnik će Vam propisati folatnu kiselinu (vitamin) koja se uzima kroz usta ili multivitaminski pripravak koji sadrži folatnu kiselinu (350 do 1000 mikrograma), koji morate uzimati jedanput na dan za vrijeme liječenja lijekom Pemetrexed Krka.
English: Limited clinical data from a separate randomized, Phase 3, controlled trial, suggest that efficacy data (overall survival, progression-free survival) for pemetrexed are similar between patients previously pre-treated with docetaxel (N=41) and patients who did not receive previous docetaxel treatment (N=540).
Croatian: Ograničeni klinički podaci iz zasebnog randomiziranog kontroliranog ispitivanja faze III ukazuju na to da su podaci o djelotvornosti (ukupno preživljenje, preživljenje bez progresije bolesti) za pemetreksed podjednaki u bolesnika prethodno liječenih docetakselom (N=41) i bolesnika koji prethodno nisu primali docetaksel (N=540).
English: Pemetrexed Krka is available in transparent glass vials containing either 100 mg or 500 mg pemetrexed.
Croatian: Pemetrexed Krka je dostupan u prozirnim staklenim bočicama koji sadrže 100 mg ili 500 mg pemetrekseda.
English: Many of the patients in whom these occurred had underlying risk factors for the development of renal events, including dehydration or pre-existing hypertension or diabetes.
Croatian: Mnogi bolesnici u kojih se to dogodilo imali su podležeće čimbenike rizika za razvoj bubrežnih događaja, uključujući dehidraciju,
English: Use an inactivated vaccine where it exists (poliomyelitis) (see section
Croatian: Treba koristiti inaktivirano cjepivo, ako postoji (poliomijelitis) (vidjeti dio 4.4).
English: Pemetrexed Krka (pemetrexed) is a multi-targeted anti-cancer antifolate agent that exerts its action by disrupting crucial folate-dependent metabolic processes essential for cell replication.
Croatian: Pemetrexed Krka (pemetrexed) je protutumorski lijek s višestrukim antifolatnim djelovanjem koji djeluje tako da prekida ključne metaboličke procese ovisne o folatima neophodne za umnažanje stanica.
English: Efficacy of pemetrexed vs. docetaxel in NSCLC - ITT population
Croatian: Djelotvornost pemetrekseda u odnosu na docetaksel kod NSCLC - ITT populacija
English: ****Combined term includes increased serum/blood creatinine, decreased glomerular filtration rate, renal failure and renal/genitourinary- other.
Croatian: **** Združeni termin obuhvaća povišene vrijednosti kreatinina u serumu/krvi, smanjenu brzinu glomerularne filtracije, zatajenje bubrega i ostale poremećaje bubrega/genitourinarnog sustava.
English: Pemetrexed Krka should be administered as an intravenous infusion over 10 minutes on the first day of each 21-day cycle.
Croatian: Pemetrexed Krka se mora primjenjivati u obliku intravenske infuzije u trajanju od 10 minuta prvog dana svakog 21-dnevnog ciklusa.
English: Pemetrexed + Cisplatin Gemcitabine + Cisplatin
Croatian: p-vrijednost za superiornost pemetreksed+cisplatin gemcitabin+cisplatin
English: For precautions to be taken before handling or administering Pemetrexed Krka, see section 6.6.
Croatian: Za mjere opreza koje je potrebno poduzeti prije rukovanja ili primjene lijeka Pemetrexed Krka, vidjeti dio 6.6.
English: Excipient with known effect Each vial contains approximately 11 mg (0.48 mmol) sodium.
Croatian: Pomoćna tvar s poznatim učinkom Jedna bočica sadrži približno 11 mg (0,48 mmol) natrija.
English: For storage conditions after reconstitution and dilution of the medicinal product, see section 6.3.
Croatian: Uvjete čuvanja nakon rekonstitucije i razrjeđenja lijeka vidjeti u dijelu 6.3.
English: **In the pemetrexed/cisplatin arm, randomized and treated (N=225) and fully supplemented (N=167).
Croatian: ** Skupina liječena kombinacijom pemetreksed/cisplatin, randomizirani i liječeni bolesnici (N = 225) i bolesnici s potpunim nadomjeskom (N = 167).
English: Excipient with known effect Each vial contains approximately 54 mg (2.35 mmol) sodium.
Croatian: Pomoćna tvar s poznatim učinkom Jedna bočica sadrži približno 54 mg (2,35 mmol) natrija.
English: Patients received a median of 4 cycles of maintenance treatment with pemetrexed and 4 cycles of placebo.
Croatian: od 4 ciklusa terapije održavanja pemetreksedom i 4 ciklusa placeba.
English: Pemetrexed*** (N=800)
Croatian: Pemetreksed*** (N=800)
English: Docetaxel (N=276)
Croatian: Docetaksel (N=276)
English: In patients with normal renal function (creatinine clearance ≥ 80 ml/min), high doses of non-steroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen > 1600 mg/day) and acetylsalicylic acid at higher doses (≥ 1.3 g daily) may decrease pemetrexed elimination and, consequently, increase the occurrence of pemetrexed adverse events.
Croatian: U bolesnika s normalnom funkcijom bubrega (klirens kreatinina ≥ 80 ml/min) visoke doze nesteroidnih protuupalnih lijekova (NSAIL, npr. ibuprofen > 1600 mg na dan) i više doze acetilsalicilatne kiseline (≥ 1,3 g na dan) mogu smanjiti eliminaciju pemetrekseda i, posljedično povećati pojavu nuspojava izazvanih pemetreksedom.
English: - The other ingredients are mannitol, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment) (E524).
Croatian: - Drugi sastojci su manitol, kloridna kiselina (za podešavanje pH), natrijev hidroksid (za podešavanje pH) (E524).
English: Excipients: mannitol, hydrochloric acid, sodium hydroxide (E524).
Croatian: Pomoćne tvari: manitol, kloridna kiselina, natrijev hidroksid (E524).
English: Other medicines and Pemetrexed Krka
Croatian: Drugi lijekovi i Pemetrexed Krka
English: As with other potentially toxic anti-cancer agents, care should be exercised in the handling and preparation of pemetrexed infusion solutions.
Croatian: Kao i kod svih potencijalno toksičnih protutumorskih lijekova, treba biti oprezan pri rukovanju i pripremi otopine pemetrekseda za infuziju.
English: Pemetrexed Krka 500 mg contains 54 mg sodium (main component of cooking/table salt) per vial.
Croatian: Pemetrexed Krka 500 mg sadrži 54 mg natrija (glavni sastojak kuhinjske/stolne soli) po bočici.
English: Clinically relevant Grade 3 and Grade 4 laboratory toxicities were similar between integrated Phase 2 results from three single-agent pemetrexed studies (N=164) and the Phase 3 single-agent pemetrexed study described above, with the exception of neutropenia (12.8% versus 5.3%, respectively) and alanine aminotransferase elevation (15.2% versus 1.9%, respectively).
Croatian: Klinički značajni oblici toksičnosti stupnja 3 i 4 utvrđeni laboratorijskim pretragama bili su podjednaki u objedinjenim rezultatima triju ispitivanja faze II pemetrekseda u monoterapiji (n=164) i rezultatima gore opisanog kliničkog ispitivanja faze III pemetrekseda u monoterapiji, s iznimkom neutropenije (12,8% naspram 5,3%) i povišenih vrijednosti alanin aminotransferaze (15,2% naspram 1,9%).
English: There is no relevant use of Pemetrexed Krka in the paediatric population in malignant pleural mesothelioma and non-small cell lung cancer.
Croatian: Nema relevantne primjene lijeka Pemetrexed Krka u pedijatrijskoj populaciji za indikaciju malignog pleuralnog mezotelioma i raka pluća nemalih stanica.
English: Fully supplemented patients
Croatian: Bolesnici s potpunim nadomjestkom
English: Grade toxicit y (%)
Croatian: Toksičnos stupnjevi toksičnost i (%)
English: Use aseptic techniques during the reconstitution and further dilution of pemetrexed for intravenous infusion administration.
Croatian: Koristiti aseptičku tehniku kod rekonstitucije i daljnjeg razrjeđivanja pemetrekseda za primjenu u intravenskoj infuziji.
English: Rare (may affect up to 1 in 1,000 people) - Radiation recall (a skin rash like severe sunburn) which can occur on skin that has previously been exposed to radiotherapy, from days to years after the radiation - Bullous conditions (blistering skin diseases)-including Stevens-Johnson syndrome and Toxic epidermal necrolysis
Croatian: Rijetko (mogu se javiti u manje od 1 na 1000 osoba) - radijacijski „recall“ dermatitis (kožni osip poput teške opekline od sunca) koji se može pojaviti na koži prethodno izloženoj zračenju, više dana ili više godina nakon zračenja - bulozna stanja (bolesti kože kod kojih se stvaraju mjehurići na koži) - uključujući Stevens
English: Pemetrexed Krka is also given in combination with cisplatin for the initial treatment of patients with advanced stage of lung cancer.
Croatian: Pemetrexed Krka se također primjenjuje u kombinaciji s cisplatinom za početno liječenje bolesnika s uznapredovalim stadijem raka pluća.
English: For instructions on reconstitution and dilution of Pemetrexed Krka before administration, see section 6.6.
Croatian: Za upute o rekonstituciji i razrjeđivanju lijeka Pemetrexed Krka prije primjene vidjeti dio 6.6.
English: If you have had or are going to have radiation therapy, please tell your doctor, as there may be an early or late radiation reaction with Pemetrexed Krka.
Croatian: Ako ste primali ili ćete primati terapiju zračenjem, obavijestite o tome svog liječnika jer se uz primjenu lijeka Pemetrexed Krka mogu pojaviti rane ili kasne reakcije na zračenje.
English: If patients develop non-haematologic toxicities ≥ Grade 3 (excluding neurotoxicity), Pemetrexed Krka should be withheld until resolution to less than or equal to the patient's pre-therapy value.
Croatian: Razvije li se u bolesnika nehematološka toksičnost stupnja ≥ 3 (osim neurotoksičnosti), primjena lijeka Pemetrexed Krka mora se prekinuti dok se vrijednosti ne vrate na razinu prije liječenja ili nižu.
English: - If you experience bleeding from the gums, nose or mouth or any bleeding that would not stop, reddish or pinkish urine, unexpected bruising (since you might have less platelets than normal which is very common).
Croatian: - ako imate krvarenje iz desni, nosa ili usta ili bilo kakvo krvarenje koje ne prestaje, crvenkastu ili ružičastu boju mokraće, neočekivane modrice (jer broj krvnih pločica može biti niži od normalnog, što je vrlo česta pojava).
English: 75% of previous dose (both Pemetrexed Krka and cisplatin)
Croatian: 75% prethodne doze (i lijeka Pemetrexed Krka i cisplatina)
English: Each 100 mg vial contains an excess of pemetrexed to facilitate delivery of the label amount.
Croatian: Jedna bočica od 100 mg sadrži pemetreksed u suvišku kako bi se olakšala primjena deklarirane količine lijeka.
English: Dose of Pemetrexed Krka (mg/m
Croatian: Doza lijeka Pemetrexed Krka (mg/m
English: A Phase 2 study of pemetrexed in 31 solid tumour patients with stable third-space fluid demonstrated no difference in pemetrexed dose normalized plasma concentrations or clearance compared to patients without third-space fluid collections.
Croatian: U ispitivanju pemetrekseda faze II u 31 bolesnika sa solidnim tumorom i stabilnom tekućinom u transcelularnom prostoru nije uočena razlika u koncentracijama pemetrekseda u plazmi normaliziranima za dozu, kao ni u klirensu pemetrekseda, u usporedbi s bolesnicima koji nisu imali nakupljanje tekućine u transcelularnom prostoru.
English: 100% of previous dose a
Croatian: 100% prethodne doze a
English: 50% of previous dose (both Pemetrexed Krka and cisplatin)
Croatian: 50% prethodne doze (i lijeka Pemetrexed Krka i cisplatina)
English: Patients should be monitored for myelosuppression during therapy and pemetrexed should not be given to patients until absolute neutrophil count (ANC) returns to ≥ 1,500 cells/mm
Croatian: U bolesnika se tijekom liječenja moraju pratiti pokazatelji mijelosupresije i pemetreksed se ne smije davati sve dok apsolutni broj neutrofila (ABN) ne bude ≥ 1500 stanica/mm a broj trombocita  100 000 stanica/mm
English: Progression-free survival (PFS) and overall response rate were similar between treatment arms: median PFS was 4.8 months for pemetrexed plus cisplatin versus 5.1 months for gemcitabine plus cisplatin (adjusted hazard ratio (HR) 1.04; 95% CI=0.94-1.15), and overall response rate was 30.6% (95% CI=27.3- 33.9) for pemetrexed plus cisplatin versus 28.2% (95% CI=25.0-31.4) for gemcitabine plus cisplatin.
Croatian: Preživljenje bez progresije bolesti (PFS) i stopa ukupnog odgovora bili su podjednaki između terapijskih skupina: medijan PFS-a iznosio je 4,8 mjeseci za pemetreksed i cisplatin u usporedbi s 5,1 mjeseci za gemcitabin i cisplatin (prilagođen omjer hazarda 1,04; 95% CI = 0,94-1,15), a stopa ukupnog odgovora bila je 30,6% (95% CI = 27,3-33,9) za pemetreksed i cisplatin u usporedbi s 28,2% (95% CI = 25,0-31,4) za gemcitabin i cisplatin.
English: 50% of previous dose a
Croatian: 50% prethodne doze a
English: powder for concentrate for solution for infusion
Croatian: Prašak za koncentrat za otopinu za infuziju
English: Pemetrexed Krka 500 mg powder for concentrate for solution for infusion This medicinal product contains 54 mg sodium per vial, equivalent to 2.7% of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Croatian: Pemetrexed Krka 500 mg prašak za koncentrat za otopinu za infuziju Ovaj lijek sadrži 54 mg natrija po bočici, što odgovara 2,7% maksimalnog dnevnog unosa od 2 g natrija prema preporukama Svjetske zdravstvene organizacije (SZO) za odraslu osobu.
English: Pemetrexed Krka contains sodium
Croatian: Pemetrexed Krka sadrži natrij
English: Posology Pemetrexed Krka must only be administered under the supervision of a physician qualified in the use of anti-cancer chemotherapy.
Croatian: Doziranje Pemetrexed Krka se smije primjenjivati samo pod nadzorom liječnika koji je obučen za primjenu antitumorske kemoterapije.
English: Live attenuated vaccines (except yellow fever, for which concomitant use is contraindicated): Risk of systemic, possibly fatal, disease.
Croatian: Živa atenuirana cjepiva (osim cjepiva protiv žute groznice, čija je istodobna primjena kontraindicirana).
English: Large Cell Carcinoma
Croatian: Karcinom skvamoznih stanica
English: Patients treated with pemetrexed and cisplatin required fewer transfusions (16.4% versus 28.9%, p < 0.001), red blood cell transfusions (16.1% versus 27.3%, p < 0.001) and platelet transfusions (1.8% versus 4.5%, p=0.002).
Croatian: Bolesnici liječeni pemetreksedom i cisplatinom trebali su manje transfuzija (16,4% naspram 28,9%, p < 0,001), transfuzija eritrocita (16,1% naspram 27,3%, p < 0,001) i transfuzija trombocita (1,8% naspram 4,5%, p = 0,002).
English: Patients also required lower administration of erythropoietin/darbopoietin (10.4% versus 18.1%, p < 0.001), G-CSF/GM-CSF (3.1% versus 6.1%, p=0.004), and iron preparations (4.3% versus 7.0%, p=0.021).
Croatian: U tih je bolesnika također rjeđe trebalo primijeniti eritropoetin/darbepoetin (10,4% naspram 18,1%, p<0,001), G-CSF/GM-CSF (3,1% naspram 6,1%, p = 0,004) i pripravke željeza (4,3% naspram 7,0%, p = 0,021).
English: - If you experience tiredness, feeling faint, becoming easily breathless or if you look pale (since you might have less haemoglobin than normal which is very common).
Croatian: - ako osjetite umor, nesvjesticu, nedostatak zraka ili ste blijedi (jer razina hemoglobina može biti niža od normalne, što je vrlo česta pojava).