FrancophonIA/ELRC3.0 huggingface dataset:
English: Patients with an increased risk of bradycardic events (e.g. patients without a pacemaker who have sick sinus syndrome, 2
Slovenian: V glavno študijo varnosti in učinkovitosti ticagrelorja niso bili vključeni bolniki s tveganjem bradikardnih dogodkov (npr. bolniki brez srčnega spodbujevalnika in z boleznijo sinusnega vozla, AV-blokom 2. ali 3. stopnje ali sinkopo zaradi bradikardije).
English: Diarrhoea, Nausea, Dyspepsia, Constipation
Slovenian: navzea, dispepsija, zaprtost retroperitonealna krvavitev
English: Titanium dioxide (E171) Iron oxide yellow (E172) Macrogol 400
Slovenian: Obloga tablete smukec titanov dioksid (E171) rumeni železov oksid (E172) makrogol 400 hipromeloza (E464)
English: • Bruising
Slovenian: • srbenje
English: Do not take Brilique if:
Slovenian: Ne jemljite zdravila Brilique
English: No dose adjustment is necessary for patients with mild hepatic impairment (see section 5.2).
Slovenian: Bolnikom z blago okvaro jeter odmerka ni treba prilagoditi (glejte poglavje 5.2).
English: Talk to your doctor before taking this medicine if you are breast-feeding.
Slovenian: Preden vzamete to zdravilo, se morate posvetovati z zdravnikom če dojite.
English: The superiority of ticagrelor over clopidogrel in reducing major CV events was not significantly affected by patient CYP2C19 or ABCB1 genotype.
Slovenian: Genotip CYP2C19 ali ABCB1 ni bistveno vplival na superiornost ticagrelorja v primerjavi s klopidogrelom za zmanjšanje hudih kardiovaskularnih dogodkov.
English: No dose adjustment is required in elderly (see section 5.2).
Slovenian: Starejši bolniki Starejšim bolnikom odmerka ni treba prilagoditi (glejte poglavje 5.2).
English: Brilique 90 mg film-coated tablets ticagrelor
Slovenian: Brilique 90 mg filmsko obložene tablete ticagrelor
English: Respiratory, thoracic and mediastinal disorders
Slovenian: Bolezni dihal, prsnega koša in mediastinalnega prostora dispneja krvavitev v dihalih
English: Ticagrelor is well tolerated in single doses up to 900 mg. Gastrointestinal toxicity was dose-limiting in a single ascending dose study.
Slovenian: Bolniki ticagrelor dobro prenašajo v enkratnih odmerkih do 900 mg.
English: Stroke
Slovenian: Operacija
English: See a doctor straight away if you notice any of the following - you may need urgent medical treatment:
Slovenian: Morda boste potrebovali nujno zdravniško pomoč:
English: What Brilique looks like and contents of the pack Film-coated tablet (tablet): The tablets are round, biconvex, yellow, film-coated marked with a “90” above “T” on one side.
Slovenian: Filmsko obložena tableta (tableta): Tablete so okrogle, na obeh straneh izbočene, rumene filmsko obložene tablete z oznako "90" nad "T" na eni strani.
English: Therefore, only Brilique 60 mg twice daily co-administered with ASA is recommended for the prevention atherothrombotic events (CV death, MI and stroke) in patients with a history of MI and a high risk of developing an atherothrombotic event.
Slovenian: Zato je pri bolnikih z anamnezo miokardnega infarkta in velikega tveganja za aterotrombotične dogodke za preprečevanje aterotrombotičnih dogodkov (kardiovaskularna smrt, miokardni infarkt in možganska kap) priporočljivo uporabljati le zdravilo Brilique 60 mg dvakrat na dan skupaj z ASA.
English: ICH
Slovenian: IKK
English: Patients self-identified as black had an 18% lower bioavailability of ticagrelor compared to Caucasian patients, in clinical pharmacology studies, the exposure (Cmax and AUC) to ticagrelor in
Slovenian: Bolniki, ki so se opredelili za črnce, so imeli 18 % manjšo biološko uporabnost ticagrelorja kot bolniki-belci.
English: Brilique 90 mg tablets ticagrelor
Slovenian: Brilique 90 mg tablete ticagrelor
English: TIMI-defined bleeding categories
Slovenian: Kategorije krvavitev, opredeljene po TIMI Hude po TIMI
English: PLATO Major or Minor
Slovenian: Hude ali blage po PLATO
English: PLATO-defined bleeding categories
Slovenian: Kategorije krvavitev, opredeljene po PLATO Hude po PLATO
English: How to store Brilique
Slovenian: Kako deluje zdravilo Brilique
English: Always take this medicine exactly as your doctor has told you.
Slovenian: kot vam naroči zdravnik.
English: • perforated unit-dosed blisters in a carton of 100x1 tablets Not all pack sizes may be marketed.
Slovenian: • perforiranih pretisnih omotih za enkratni odmerek v škatli s 100 x 1 tableto.
English: What Brilique is
Slovenian: Kaj je zdravilo Brilique
English: • Nosebleed
Slovenian: • podplutbe
English: Tablet coating Talc
Slovenian: KOLEDARSKI PRETISNI OMOT
English: EXPIRY DATE
Slovenian: Dnevi od randomizacije
English: Secondary endpoint
Slovenian: Sekundarni opazovani dogodek
English: SOC Very common Common
Slovenian: Zelo pogosti
English: Treatment with Brilique 90 mg twice daily is recommended for 12 months in ACS patients unless discontinuation is clinically indicated (see section 5.1).
Slovenian: Zdravljenje z zdravilom Brilique je treba začeti z enim 180-mg polnilnim odmerkom (dve tableti po 90 mg) in ga nadaljevati z 90 mg dvakrat na dan. Zdravljenje z zdravilom Brilique 90 mg je pri bolnikih z AKS priporočljivo nadaljevati 12 mesecev, razen če je prenehanje z zdravljenjem klinično indicirano (glejte poglavje 5.1).
English: AstraZeneca S.p.A. Tel: +39 02 9801 1
Slovenian: Tel: + 39 02 9801 1
English: TIMI Requiring medical attention: Requiring intervention, OR leading to hospitalisation, OR prompting evaluation.
Slovenian: Blage po TIMI: Klinično opazna z znižanjem hemoglobina od 30 do50 g/l TIMI s potrebo po medicinski oskrbi: Zahteva ukrepanje ALI povzroči sprejem v bolnišnico ALI zahteva ovrednotenje.
English: Dizziness, Syncope, Headache
Slovenian: Bolezni živčevja omotica, sinkopa, glavobol intrakranialna krvavitev
English: An updated RMP shall be submitted every three years.
Slovenian: Posodobljen RMP je treba predložiti vsake tri leta.
English: Thus it is important to regularly measure blood pressure to verify if it is within the normal range.
Slovenian: Torej je potrebno krvni tlak redno meriti, da bi lahko preverili, ali je v normalnem območju.
English: The tablets should be swallowed with some water or other non-alcoholic drink.
Slovenian: Tablete morate pogoltniti z nekaj vode ali brezalkoholne pijače.
English: See also information under the heading “Do not take MicardisPlus”.
Slovenian: Glejte tudi informacije pod naslovom “Ne jemljite zdravila MicardisPlus”.
English: Your doctor will normally advise you to stop taking MicardisPlus before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of MicardisPlus.
Slovenian: Zdravnik vam bo praviloma svetoval, da zdravilo MicardisPlus prenehate jemati, preden boste zanosili ali takoj, ko boste vedeli, da ste noseči, in vam svetoval, da namesto zdravila MicardisPlus jemljete drugo zdravilo.
English: Date of latest renewal: 23 April 2007
Slovenian: Datum prve odobritve: 19. april 2002 Datum zadnjega podaljšanja: 23. april 2007
English: MicardisPlus can have influence on the ability to drive and use machines.
Slovenian: Zdravilo MicardisPlus lahko vpliva na sposobnost vožnje in upravljanja strojev.
English: The European Medicines Agency has waived the obligation to submit the results of studies with MicardisPlus in all subsets of the paediatric population in hypertension (see section 4.2 for information on paediatric use).
Slovenian: Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom MicardisPlus za vse podskupine pediatrične populacije s hipertenzijo (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
English: MicardisPlus with food and alcohol
Slovenian: Zdravilo MicardisPlus skupaj s hrano in alkoholom
English: If you take more MicardisPlus than you should If you accidentally take too many tablets you may experience symptoms such as low blood pressure and rapid heartbeat.
Slovenian: Če ste vzeli večji odmerek zdravila MicardisPlus, kot bi smeli Če pomotoma vzamete preveč tablet, se lahko pojavijo simptomi, kot so nizek krvni tlak in pospešen srčni utrip.
English: What MicardisPlus is and what it is used for
Slovenian: Kaj je zdravilo MicardisPlus in za kaj ga uporabljamo
English: DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation:19 April 2002
Slovenian: DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Z ZDRAVILOM Datum prve odobritve: 19. april 2002 Datum zadnjega podaljšanja: 23. april 2007
English: Adverse reactions have been ranked under headings of frequency using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Slovenian: Neželeni učinki so razvrščeni po pogostnosti, za katero veljajo naslednji kriteriji: zelo pogosti (≥ 1/10); pogosti (≥ 1/100 do < 1/10); občasni (≥ 1/1.000 do < 1/100); redki (≥ 1/10.000 do < 1/1.000); zelo redki (< 1/10.000), neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
English: There are no adequate data from the use of MicardisPlus in pregnant women.
Slovenian: Ni zadostnih podatkov o uporabi zdravila MicardisPlus pri nosečnicah.
English: Erectile dysfunction
Slovenian: erektilna disfunkcija
English: Some people feel dizzy or tired when taking MicardisPlus.
Slovenian: Nekateri ljudje so med zdravljenjem z zdravilom MicardisPlus omotični ali utrujeni.
English: The primary treatment is to discontinue hydrochlorothiazide as rapidly as possible.
Slovenian: Primarno zdravljenje je, čim hitrejša prekinitev uporabe hidroklorotiazida.
English: • Second and third trimesters of pregnancy (see sections 4.4 and 4.6).
Slovenian: • drugo in tretje trimesečje nosečnosti (glejte poglavji 4.4 in 4.6),
English: Greece and
Slovenian: Grčija in
English: You should consult with your doctor if you need to adjust the dose of your other medicine while taking MicardisPlus.
Slovenian: Z zdravnikom se morate posvetovati, ali je treba med jemanjem zdravila MicardisPlus prilagoditi odmerek vašega drugega zdravila.
English: The safety and efficacy of MicardisPlus in children and adolescents aged below 18 have not been established.
Slovenian: Varnost in učinkovitost zdravila MicardisPlus pri otrocih in mladostnikih, mlajših od 18 let, še nista bili dokazani.
English: • Hypersensitivity to other sulphonamide-derived substances (since hydrochlorothiazide is a sulphonamide-derived medicinal product).
Slovenian: • preobčutljivost na druge sulfonamidne derivate (ker je hidroklorotiazid sulfonamidni derivat),
English: • if you are allergic to telmisartan or any other ingredients of this medicine (listed in section 6)
Slovenian: • če ste alergični na telmisartan ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
English: It is important that you take MicardisPlus every day until your doctor tells you otherwise.
Slovenian: Zdravilo MicardisPlus morate jemati vsak dan, dokler vam ga bo zdravnik predpisoval.
English: What you need to know before you take MicardisPlus
Slovenian: Kaj morate vedeti, preden boste vzeli zdravilo MicardisPlus
English: Children and adolescents The use of MicardisPlus in children and adolescents up to the age of 18 years is not recommended.
Slovenian: Otroci in mladostniki Uporabe zdravila MicardisPlus pri otrocih in mladostnikih do 18. leta ne priporočamo.
English: Rare cases have also been reported with angiotensin II receptor antagonists (including MicardisPlus).
Slovenian: O redkih tovrstnih primerih poročajo tudi za antagoniste angiotenzina II (vključno z zdravilom MicardisPlus).
English: You can take MicardisPlus with or without food.
Slovenian: Zdravilo MicardisPlus lahko jemljete s hrano ali brez.
English: If you forget to take MicardisPlus
Slovenian: Če ste pozabili vzeti zdravilo MicardisPlus
English: What MicardisPlus is and what it is used for What you need to know before you take MicardisPlus How to take MicardisPlus
Slovenian: Kaj je zdravilo MicardisPlus in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo MicardisPlus Kako jemati zdravilo MicardisPlus Možni neželeni učinki
English: UNIQUE IDENTIFIER - HUMAN READABLE DATA PC: {number} {product code}
Slovenian: EDINSTVENA OZNAKA - V BERLJIVI OBLIKI PC: {številka} [koda zdravila]
English: Such conditions should be corrected before the administration of MicardisPlus.
Slovenian: Tovrstna stanja je treba uravnati pred zdravljenjem z zdravilom MicardisPlus.
English: MicardisPlus is a combination of two active substances, telmisartan and hydrochlorothiazide in one tablet.
Slovenian: Zdravilo MicardisPlus je kombinacija dveh zdravilnih učinkovin, telmisartana in hidroklorotiazida v eni tableti.
English: Possible side effects of MicardisPlus:
Slovenian: Možni neželeni učinki zdravila MicardisPlus so:
English: In a follow-up trial with the 80 mg/25 mg combination, blood pressure was further decreased (resulting in an overall reduction of 11.5/9.9 mm Hg (SBP/DBP).
Slovenian: V nadaljni raziskavi s kombinacijo 80 mg/25 mg se je krvni tlak nadalje znižal (skupno za 11,5/9,9 mm Hg) (AKT/DKT).
English: • if you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren.
Slovenian: • če imate sladkorno bolezen ali okvaro delovanja ledvic in se zdravite z zdravilom za znižanje krvnega tlaka, ki vsebuje aliskiren.
English: An increase in cholesterol and triglyceride levels has been associated with thiazide diuretic therapy; however, at the 12.5 mg dose contained in MicardisPlus, minimal or no effects were reported.
Slovenian: Z zdravljenjem s tiazidnimi diuretiki povezujejo povečanje ravni holesterola in trigliceridov, vendar za odmerek po 12,5 mg, ki ga vsebuje zdravilo MicardisPlus, poročajo le o minimalnih ali nikakršnih tovrstnih učinkih.
English: MicardisPlus is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Slovenian: Zdravila MicardisPlus med nosečnostjo ne priporočajo; ne smete pa ga jemati, ko boste noseči več kot 3 mesece, ker lahko po tretjem mesecu nosečnosti resno škoduje vašemu otroku.
English: MicardisPlus is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section).
Slovenian: Uporaba zdravila MicardisPlus ni priporočljiva v zgodnjem obdobju nosečnosti in ga ne smete jemati, če ste noseči več kot 3 mesece, ker lahko v tem obdobju resno škoduje vašemu otroku (glejte poglavje o nosečnosti).
English: Experience with MicardisPlus is modest in the patients with mild to moderate renal impairment, therefore periodic monitoring of potassium, creatinine and uric acid serum levels is recommended.
Slovenian: Z zdravilom MicardisPlus je malo izkušenj pri bolnikih z blago do zmerno zmanjšanim delovanjem ledvic, zato so priporočljivi periodični kontrolni pregledi serumskih ravni kalija, kreatinina in sečne kisline.
English: MicardisPlus contains milk sugar (lactose) and sorbitol.
Slovenian: Zdravilo MicardisPlus vsebuje mlečni sladkor (laktozo) in sorbitol.
English: In case of surgery or anaesthetics, you should tell your doctor that you are taking MicardisPlus.
Slovenian: Če boste operirani ali boste dobili anestetike, morate zdravniku povedati, da jemljete zdravilo MicardisPlus.
English: No additional preclinical studies have been performed with the Fixed Dose Combination product 80 mg/25 mg.
Slovenian: Dodatnih predkliničnih raziskav s fiksno kombinacijo zdravila 80 mg/25 mg niso izvedli.
English: MicardisPlus 40 mg/12.5 mg tablets EU/1/02/213/001-005, 011, 013-014
Slovenian: MicardisPlus 40 mg/12,5 mg tablete EU/1/02/213/001-005, 011, 013-014
English: MicardisPlus must not be used in patients with severe renal impairment (creatinine clearance <30 ml/min) (see section 4.3).
Slovenian: Zdravila MicardisPlus ne smemo dajati bolnikom z močno zmanjšanim delovanjem ledvic (kreatininskim očistkom < 30 ml/min) (glejte poglavje 4.3).
English: Do not take MicardisPlus
Slovenian: Ne jemljite zdravila MicardisPlus
English: Rottendorf Pharma GmbH Ostenfelder Straße 51 - 61 D-59320 Ennigerloh
Slovenian: Rottendorf Pharma GmbH Ostenfelder Straße 51 - 61 D-59320 Ennigerloh Nemčija
English: MicardisPlus 80 mg/12.5 mg tablets EU/1/02/213/006-010, 012, 015-016
Slovenian: MicardisPlus 80 mg/12,5 mg tablete EU/1/02/213/006-010, 012, 015-016
English: Because no information is available regarding the use of MicardisPlus during breast-feeding, MicardisPlus is not recommended and alternative treatments with better established safety profiles during breast-feeding are preferable, especially while nursing a newborn or preterm infant.
Slovenian: Ker o uporabi zdravila MicardisPlus med dojenjem ni podatkov, ga ne priporočajo, zato je treba med dojenjem, še zlasti med dojenjem novorojenčkov ali prezgodaj rojenih dojenčkov, dajati prednost alternativnim zdravilom, katerih varnostne lastnosti so bolj raziskane.
English: The use of MicardisPlus during breast feeding is not recommended.
Slovenian: Uporabe zdravila MicardisPlus med dojenjem ne priporočajo.
English: Other medicines and MicardisPlus:
Slovenian: Druga zdravila in zdravilo MicardisPlus
English: Coadministration of lithium and MicardisPlus is not recommended (see section 4.4).
Slovenian: Sočasno dajanje litija in zdravila MicardisPlus ne priporočamo (glejte poglavje 4.4).
English: Hydrochlorothiazide: Following oral administration of MicardisPlus peak concentrations of hydrochlorothiazide are reached in approximately 1.0 - 3.0 hours after dosing.
Slovenian: Hidroklorotiazid: Po peroralnem dajanju zdravila MicardisPlus doseže hidroklorotiazid največjo koncentracijo v plazmi približno v 1,0 do 3,0 urah.
English: The concomitant use of MicardisPlus with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 ml/min/1.73 m2) (see sections 4.5 and 5.1).
Slovenian: Sočasna uporaba zdravila MicardisPlus in zdravil, ki vsebujejo aliskiren je kontraindicirana pri bolnikih s sladkorno boleznijo ali z okvaro ledvic (hitrost glomerularne filtracije < 60 ml/min/1,73 2) (glejte poglavji 4.5 in 5.1).
English: MicardisPlus once daily produces effective and smooth reductions in blood pressure across the therapeutic dose range.
Slovenian: Zdravilo MicardisPlus v enem odmerku na dan učinkovito in enakomerno znižuje krvni tlak v celotnem razponu odmerjanja.
English: • Severe renal impairment (creatinine clearance < 30 ml/min).
Slovenian: • huda ledvična okvara (kreatininski očistek < 30 ml/min),
English: MicardisPlus may increase the blood pressure lowering effect of other medicines used to treat high blood pressure or of medicines with blood pressure lowering potential (e.g. baclofen, amifostine).
Slovenian: Zdravilo MicardisPlus lahko poveča antihipertenzivni učinek drugih zdravil, ki znižujejo krvni tlak, ali zdravil z možnim antihipertenzivnim učinkom (npr. baklofen, amifostin).
English: Sialadenitis Neoplasms benign, malignant and unspecified (incl cysts and polyps) Not known:
Slovenian: sialoadenitis Benigne, maligne in neopredeljene novotvorbe (vključno s cistami in polipi) Neznana:
English: MARKETING AUTHORISATION NUMBER(S) EU/1/02/213/017-023
Slovenian: EU/1/02/213/017-023
English: • if your doctor determines that you have low potassium levels or high calcium levels in your blood that do not get better with treatment.
Slovenian: • če vaš zdravnik odkrije, da imate nizko raven kalija ali visoko raven kalcija v krvi in da tega stanja zdravljenje ne izboljša.
English: MicardisPlus may be less effective in lowering the blood pressure in black patients.
Slovenian: Zdravilo MicardisPlus lahko pri črni rasi manj učinkovito znižuje krvni tlak.
English: Remove your MicardisPlus tablet from the blister only directly prior to intake.
Slovenian: Tableto zdravila MicardisPlus vzemite iz pretisnega omota tik, preden jo boste zaužili.
English: • if you have severe liver problems such as cholestasis or biliary obstruction (problems with drainage of the bile from the liver and gall bladder) or any other severe liver disease.
Slovenian: • če imate hude jetrne težave, kot sta holestaza ali zapora žolčevoda (težave z odtekanjem žolča iz jeter in žolčnika), ali katerokoli drugo hudo jetrno bolezen;
English: Non-steroidal anti-inflammatory medicinal products NSAIDs (i.e. acetylsalicylic acid at anti-inflammatory dosage regimens, COX-2 inhibitors and nonselective NSAIDs) may reduce the diuretic, natriuretic and antihypertensive effects of thiazide diuretics and the antihypertensive effects of angiotensin II receptor antagonists.
Slovenian: Nesteroidna protivnetna zdravila (acetilsalicilna kislina v odmerkih, ki učinkujejo protivnetno, zaviralci ciklooksigenaze 2 in neselektivna nesteroidna protivnetna zdravila) lahko zmanjšajo diuretične, natriuretične in antihipertenzivne učinke tiazidnih diuretikov ter antihipertenzivne učinke antagonistov receptorjev angiotenzina II.
English: • Refractory hypokalaemia, hypercalcaemia.
Slovenian: • refraktarna hipokaliemija, hiperkalcemija.
English: If any of the above applies to you, tell your doctor or pharmacist before taking MicardisPlus.
Slovenian: Če imate katero od naštetih stanj, povejte zdravniku ali farmacevtu preden boste vzeli zdravilo MicardisPlus.
English: In patients whose vascular tone and renal function depend predominantly on the activity of the reninangiotensin-aldosterone system (e.g. patients with severe congestive heart failure or underlying renal disease, including renal artery stenosis), treatment with medicinal products that affect this system has been associated with acute hypotension, hyperazotaemia, oliguria, or rarely acute renal failure (see section 4.8).
Slovenian: Če sta žilni tonus in delovanje ledvic pretežno odvisna od delovanja renin-angiotenzinaldosteronskega sistema (npr. pri bolnikih s hudim kongestivnim srčnim popuščanjem ali ledvično boleznijo, tudi zožitvijo ledvične arterije), povezujejo zdravljenje z zdravili, katera delujejo na ta sistem, z akutno hipotenzijo, s hiperazotemijo, oligurijo in, redko, z akutno ledvično odpovedjo (glejte poglavje 4.8).
English: These could be symptoms of an increase of pressure in your eye and can happen within hours to weeks of taking MicardisPlus.
Slovenian: Oba sta lahko tudi simptoma zvišanega očesnega tlaka, ki se pojavita nekaj ur do nekaj tednov po začetku jemanja zdravila MicardisPlus.
English: MicardisPlus should not be given to patients with cholestasis, biliary obstructive disorders or severe hepatic insufficiency (see section 4.3) since telmisartan is mostly eliminated with the bile.
Slovenian: Zdravila MicardisPlus ne smemo dajati bolnikom s holestazo, z obolenji z zaporo žolčevoda ali močno zmanjšanim delovanjem jeter (glejte poglavje 4.3), ker se telmisartan v glavnem izloča z žolčem.
English: If you are intolerant to some sugars, consult your doctor before taking MicardisPlus.
Slovenian: Če nekaterih sladkorjev ne prenašate, se pred uporabo zdravila MicardisPlus posvetujte s svojim zdravnikom.
English: Conversely, due to the antagonism of the angiotensin II (AT1) receptors by the telmisartan component of MicardisPlus, hyperkalaemia might occur.
Slovenian: Zaradi antagonističnega delovanja telmisartana v zdravilu MicardisPlus na receptorje za angiotenzin II (AT1) je možna tudi hiperkaliemija.
English: In addition, MicardisPlus should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.
Slovenian: Zdravila MicardisPlus moramo previdno dajati tudi bolnikom z motnjami v delovanju jeter ali napredujočo jetrno boleznijo, ker lahko že manjše spremembe ravnovesja tekočin in elektrolitov povzročijo jetrno komo.
English: • Hypersensitivity to any of the active substances or to any of the excipients listed in section 6.1.
Slovenian: • Preobčutljivost na katero koli učinkovino ali katero koli pomožno snov, navedeno v poglavju
English: If your liver is not working properly, the usual dose should not exceed 40 mg/12.5 mg once a day.
Slovenian: Če imate motnje v delovanju jeter, običajni odmerek ne sme prekoračiti 40 mg/12,5 mg enkrat na dan.