FrancophonIA/ELRC3.0 huggingface dataset:
English: In the therapeutic studies no dosage adjustment was made on the basis of age.
Slovenian: V terapevtskih študijah odmerjanja niso prilagajali glede na starost.
English: The severity of the adverse reactions was generally mild to moderate.
Slovenian: Resnost neželenih učinkov je bila na splošno blaga do zmerna.
English: The volume of distribution at steady state for voriconazole is estimated to be 4.6 L/kg, suggesting extensive distribution into tissues.
Slovenian: Ocenjeni volumen porazdelitve vorikonazola v stanju dinamičnega ravnovesja je 4,6 l/kg, kar nakazuje na znatno porazdelitev v tkiva.
English: Dosage adjustment (Children [2 to <12 years] and young adolescents with low body weight [12 to 14 years and <50 kg])
Slovenian: Prilagajanje odmerka (otroci [2 do < 12 let] in mlajši mladostniki z majhno telesno maso [12 do 14 let in < 50 kg])
English: For Caucasians and Blacks the prevalence of poor metabolisers is 3-5 %.
Slovenian: Med belci in črnci je prevalenca oseb z zmanjšano presnovo 3- 5 %.
English: Aspergillus infections - efficacy in aspergillosis patients with poor prognosis Voriconazole has in vitro fungicidal activity against Aspergillus spp.
Slovenian: Okužbe z Aspergillusom - učinkovitost pri bolnikih z aspergilozo s slabo prognozo Vorikonazol deluje in vitro fungicidno proti Aspergillus spp.
English: In fluconazole-resistant non albicans species, a successful outcome was seen in 3/3 C. krusei (complete responses) and 6/8 C. glabrata (5 complete, 1 partial response) infections.
Slovenian: Pri ne-albicans vrstah, odpornih na flukonazol, so uspešen odziv ugotovili pri 3/3 okužbah s C. krusei (popolni odzivi) in 6/8 okužbah s C. glabrata (5 popolnih, 1 delni odziv).
English: A relationship between plasma concentrations and age was observed.
Slovenian: Opažali so razmerje med koncentracijo v plazmi in starostjo.
English: Body Weight (kg)
Slovenian: telesna masa (kg)
English: Stability after reconstitution:
Slovenian: Stabilnost po rekonstituciji:
English: Monitoring of pancreatic function
Slovenian: Nadzor delovanja pankreasa
English: You should avoid any sunlight and sun exposure while being treated.
Slovenian: Med zdravljenjem se povsem izogibajte sončni svetlobi in izpostavljenosti soncu.
English: The species most frequently involved in causing human infections include C. albicans, C. parapsilosis, C. tropicalis, C. glabrata and C. krusei, all of which usually exhibit minimum inhibitory concentration (MICs) of less than 1 mg/L for voriconazole.
Slovenian: Vrste, ki so najpogosteje vpletene pri povzročanju okužb pri ljudeh, so C. albicans, C. parapsilosis, C. tropicalis, C. glabrata in C. krusei, pri čemer pri vseh naštetih minimalna inhibitorna koncentracija (MIK) za vorikonazol običajno znaša manj kot 1 mg/L.
English: The recommended dosing regimen is as follows:
Slovenian: Priporočena shema odmerjanja je:
English: Safety and effectiveness in paediatric subjects below the age of two years has not been established (see sections 4.8 and 5.1).
Slovenian: Varnost in učinkovitost pri otrocih, mlajših od dveh let, ni raziskana (glejte poglavji 4.8 in 5.1).
English: If VORICONAZOLE HIKMA is continued, however, dermatologic evaluation should be performed on a systematic and regular basis, to allow early detection and management of premalignant lesions.
Slovenian: Če pa se zdravljenje z zdravilom VORIKONAZOL HIKMA nadaljuje, je treba bolnike redno in sistematično dermatološko ocenjevati, da se omogoči zgodnje odkrivanje in obravnavanje predrakavih lezij.
English: Infusion of total parenteral nutrition can occur silmultaneously with Voriconazole Hikma but not in the same line or cannula.
Slovenian: Sočasna infuzija popolne parenteralne prehrane z zdravilom Vorikonazol Hikma je možna, vendar ne v isto linijo ali kanilo.
English: This represents a heterogeneous population, containing patients with haematological malignancy, HIV infected patients with oesophageal candidiasis and refractory fungal infections, non-neutropenic patients with candidaemia or aspergillosis and healthy volunteers.
Slovenian: Gre za heterogeno populacijo, ki zajema bolnike s hematološkimi malignomi, s HIV okužene bolnike s kandidiazo požiralnika in refraktarnimi glivičnimi okužbami, nenevtropenične bolnike s kandidemijo ali aspergilozo ter zdrave prostovoljce.
English: In the 22 patients less than 2 years old who received voriconazole in a compassionate use programme, the following adverse reactions (for which a relationship to voriconazole could not be excluded) were reported: photosensitivity reaction (1), arrhythmia (1), pancreatitis (1), blood bilirubin increased (1), hepatic enzymes increased (1), rash (1) and papilloedema (1).
Slovenian: Pri 22 bolnikih, mlajših od dveh let, ki so dobivali vorikonazol v programu sočutne uporabe, so poročali o naslednjih neželenih učinkih (za katere povezava z vorikonzolom ni bila izključena): fotosenzitivnostna kožna reakcija (1), aritmija (1), pankreatitis (1), zvišanje ravni bilirubina v krvi (1), zvišanje ravni jetrnih encimov (1), izpuščaj (1) in edem papile vidnega živca (1).
English: • Inflammation of the thin tissue that lines the inner wall of the abdomen and covers the abdominal organs
Slovenian: • vnetje tankega tkiva, ki obdaja notranjo steno trebuha in prekriva organe v trebuhu
English: Voriconazole exposures in the majority of adolescent patients were comparable to those in adults receiving the same dosing regimens.
Slovenian: Izpostavljenosti vorikonazolu pri večini mladostnikov so bile primerljive tistim pri odraslih, ki so prejemali enake sheme odmerjanja.
English: In the same study, no significant differences in Cmax and AUCτ were observed between healthy elderly males and healthy elderly females (≥ 65 years).
Slovenian: V isti študiji niso ugotovili pomembnih razlik C maxin AUCτ med zdravimi starejšimi moški in zdravimi starejšimi ženskami (≥ 65 let).
English: Elevated liver enzymes were also observed more frequently in children.
Slovenian: Pri otrocih so pogosteje poročali tudi o zvišanih ravneh jetrnih encimov.
English: Voriconazole has not been studied in patients with severe chronic hepatic cirrhosis (Child-Pugh C).
Slovenian: Vorikonazola niso raziskovali pri bolnikih s hudo kronično cirozo jeter (Child-Pugh C).
English: Cimetidine (400 mg BID) [non-specific CYP450 inhibitor and increases gastric pH]
Slovenian: cimetidin (400 mg BID) [non-specific CYP450 inhibitor and increases gastric pH]
English: In 10 therapeutic studies, the median for the average and maximum plasma concentrations in individual subjects across the studies was 2425 ng/ml (inter-quartile range 1193 to 4380 ng/ml) and 3742 ng/ml (interquartile range 2027 to 6302 ng/ml), respectively.
Slovenian: V 10 terapevtskih študijah je bila mediana povprečne koncentracije v plazmi pri posameznih preskušancih v vseh študijah 2425 ng/ml (interkvartilni obseg od 1193 do 4380 ng/ml), mediana največje koncentracije v plazmi pa 3742 ng/ml (interkvartilni obseg od 2027 do 6302 ng/ml).
English: Because of non-linear pharmacokinetics, the terminal half-life is not useful in the prediction of the accumulation or elimination of voriconazole.
Slovenian: Zaradi nelinearne farmakokinetike končni razpolovni čas ne pomaga predvideti kopičenja ali izločanja vorikonazola.
English: Voriconazole Cmax and AUCτ ↔ The effect of voriconazole on either erythromycin or azithromycin is unknown.
Slovenian: vorikonazol Cmax in AUCτ ↔ Učinek vorikonazola na eritromicin ali azitromicin ni znan.
English: • You are suffering from, or have ever suffered from liver disease.
Slovenian: • imate ali ste v preteklosti imeli bolezen jeter.
English: Compared to efavirenz 600 mg QD,
Slovenian: v primerjavi s 600 mg efavirenza QD,
English: All other adolescents (12 to 14 years and ≥50 kg; 15 to 17 years regardless of body weight) Voriconazole should be dosed as adults.
Slovenian: Vsi drugi mladostniki (12 do 14 let in ≥ 50 kg; 15 do 17 let ne glede na telesno maso) Vorikonazol je treba odmerjati kot pri odraslih.
English: Dose reduction of methadone may be needed.
Slovenian: Morda bo treba odmerek metadona zmanjšati.
English: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those that are obtained without a prescription.
Slovenian: Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katerokoli drugo zdravilo, tudi če ste ga dobili brez recepta.
English: The absolute bioavailability of voriconazole after oral administration is estimated to be 96 %.
Slovenian: Ocenjena absolutna biološka uporabnost vorikonazola po peroralni uporabi je 96 %.
English: For patients with ICC the global response rate at EOT was 85.7% (6/7) and for patients with EC the global response rate at EOT was 70% (7/10).
Slovenian: Pri bolnikih z ICC je bila stopnja globalnega odziva ob koncu terapije 85,7 % (6/7), pri bolnikih z EC pa je bila stopnja globalnega odziva ob koncu terapije 70 % (7/10).
English: Primary Prophylaxis of Invasive Fungal Infections - Efficacy in HSCT recipients without prior proven or probable IFI
Slovenian: Primarna profilaksa invazivnih glivičnih okužb - učinkovitost pri prejemnikih HSCT brez predhodno dokazane ali verjetne IGO
English: This should be taken into consideration for patients on a controlled sodium diet.
Slovenian: To morajo upoštevati bolniki, ki so na dieti z nadzorovanim vnosom natrija.
English: If you or your child are taking Voriconazole Hikma for prevention of fungal infections, your doctor may stop giving Voriconazole Hikma if you or your child develop treatment related side effects.
Slovenian: Če vi ali vaš otrok jemljete zdravilo Vorikonazol Hikma za preprečevanje glivičnih okužb, vam bo zdravnik morda prenehal dajati zdravilo Vrikonazol Hikma, če se pri vas ali vašem otroku pojavijo neželeni učinki, povezani z zdravljenjem
English: Serious side effects - Stop taking Voriconazole Hikma and see a doctor immediately
Slovenian: Resni neželeni učinki - prenehajte uporabljati zdravilo Vorikonazol Hikma in nemudoma poiščite zdravnika
English: • Low blood sugar, low blood potassium, low sodium in the blood
Slovenian: • nizka raven sladkorja v krvi, nizka raven kalija v krvi, nizka raven natrija v krvi
English: For patients with IA the overall rates of global response at 6 weeks were 64.3% (9/14), the global response rate was 40% (2/5) for patients 2 to <12 years and 77.8% (7/9) for patients 12 to <18 years of age.
Slovenian: Pri bolnikih z IA so bile celokupne stopnje globalnega odziva po 6 tednih 64,3 % (9/14), stopnja globalnega odziva za bolnike, stare od 2 do < 12 let, je bila 40 % (2/5), za bolnike, stare od 12 do < 18 let, pa 77,8 % (7/9).
English: Voriconazole Hikma must not be infused into the same line or cannula concomitantly with other drug infusions, including parenteral nutrition (e.g. Aminofusin 10% Plus).
Slovenian: Zdravila Vorikonazol Hikma se ne sme infundirati v isto linijo ali kanilo sočasno z infundiranjem drugih zdravil, vključno s parenteralno prehrano (npr. Aminofusin 10 % Plus).
English: In vitro activity against the following pathogens has been shown, but the clinical significance is unknown: Curvularia spp.
Slovenian: In vitro je bilo dokazano delovanje proti naslednjim patogenom, vendar klinični pomen tega ni znan:
English: The intravenous vehicle, SBECD, is haemodialysed with a clearance of 55 ml/min.
Slovenian: Intravenski vehikel SBECD se hemodializira z očistkom 55 ml/min.
English: • serious fungal infections caused by Scedosporium sp. or Fusarium sp. (two different species of fungi).
Slovenian: • s hudimi glivičnimi okužbami, ki jih povzročajo vrste Scedosporium ali Fusarium (dve različni vrsti gliv).
English: • Cisapride (used for stomach problems)
Slovenian: • cisaprid (uporablja se proti težavam z želodcem)
English: The compatibility of Voriconazole Hikma with diluents other than listed above (or listed below under ‘Incompatibilities') is unknown.
Slovenian: Združljivost zdravila Vorikonazol Hikma z drugimi tekočinami razen zgoraj naštetih (ali omenjenih spodaj pod "Inkompatibilnosti") ni znana.
English: In the clinical programme, no dosage adjustment was made on the basis of gender.
Slovenian: V kliničnem programu odmerjanja niso prilagajali glede na spol.
English: Dermatological reactions were very common in patients treated with voriconazole in clinical trials, but these patients had serious underlying diseases and were receiving multiple concomitant medicinal products.
Slovenian: V kliničnih preskušanjih so bile dermatološke reakcije pri bolnikih, zdravljenih z vorikonazolom, zelo pogoste, toda ti bolniki so imeli hude že obstoječe bolezni in so sočasno dobivali več zdravil.
English: In addition VORICONAZOLE HIKMA has been associated with phototoxicity including reactions such as ephelides, lentigo, actinic keratosis and pseudoporphyria.
Slovenian: Poleg tega je bilo zdravilo VORIKONAZOL HIKMA povezano s fototoksičnostjo, vključno z reakcijami, kot so efelide, lentigo, aktinična keratoza in psevdoporfirija.
English: 4 EUCAST has not determined non-species related breakpoints for voriconazole.
Slovenian: 4 EUCAST ni določil mejnih vrednosti za vorikonazol, ki niso povezane z vrsto.
English: Voriconazole is indicated for paediatric patients aged two years or older.
Slovenian: Vorikonazol je indiciran pri pediatričnih bolnikih, starih dve leti ali več.
English: • Everolimus (used for treating advanced kidney cancer and in transplant patients)
Slovenian: everolimus (uporablja se za zdravljenje napredovalega raka ledvic in pri bolnikih po presaditvi)
English: There is limited data on the safety of voriconazole in patients with abnormal liver function tests (aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), or total bilirubin >5 times the upper limit of normal).
Slovenian: Na voljo so omejeni podatki o varnosti vorikonazola pri bolnikih z nenormalnimi testi jetrne funkcije (aspartat-aminotransferaza [AST], alanin-aminotransferaza [ALT], alkalna fosfataza [ALP] ali celotni bilirubin > 5-kratna zgornja meja normalne vrednosti).
English: Frequent monitoring for adverse reactions and toxicity related to methadone, including QTc prolongation, is recommended.
Slovenian: Priporočljiv je pogost nadzor neželenih učinkov in toksičnosti, povezanih z metadonom, vključno s podaljšanjem QTc.
English: The effects on parturition are probably mediated by species-specific mechanisms, involving reduction of oestradiol levels, and are consistent with those observed with other azole antifungal agents.
Slovenian: Učinki na porod se verjetno posredujejo z za živalsko vrsto specifičnimi mehanizmi, ki obsegajo zmanjšanje koncentracije estradiola in se skladajo z mehanizmi, ugotovljenimi pri drugih azolskih antimikotikih.
English: If you or your child develops skin disorders, your doctor may refer you to a dermatologist, who after consultation may decide that it is important for you or your child to be seen on a regular basis.
Slovenian: Če se vam ali vašemu otroku pojavijo bolezni kože, vas bo zdravnik morda napotil k dermatologu, ki se po posvetu lahko odloči, da je pomembno, da ga redno obiskujete.
English: Voriconazole has been associated with elevations in liver function tests and clinical signs of liver damage, such as jaundice, and must only be used in patients with severe hepatic impairment if the benefit outweighs the potential risk.
Slovenian: Vorikonazol je bil povezan z zvišanjem testov jetrne funkcije in kliničnimi znaki okvare jeter, kot na primer ikterusom, zato ga smemo pri bolnikih s hudo jetrno okvaro uporabiti le, če korist odtehta možno tveganje.
English: Pharmacokinetic/pharmacodynamic relationship
Slovenian: Odnos med farmakokinetiko/farmakodinamiko
English: • Cardiomyopathy, in particular when heart failure is present
Slovenian: • kardiomiopatija, posebej ob prisotnem popuščanju srca,
English: The higher intravenous maintenance dose in paediatric patients relative to adults reflects the higher elimination capacity in paediatric patients due to a greater liver mass to body mass ratio.
Slovenian: Večji intravenski vzdrževalni odmerek pri pediatričnih bolnikih v primerjavi z odmerkom pri odraslih je posledica večje kapacitete izločanja pri pediatričnih bolnikih, ki imajo večje razmerje med maso jeter in telesno maso.
English: In an independent published study, Voriconazole AUC0-∞ ↓ 59%
Slovenian: v neodvisni, objavljeni študiji, vorikonazol AUC0-∞ ↓ 59%
English: Low dose (100 mg BID)*
Slovenian: majhni odmerki (100 mg BID)*
English: During oral administration of 200 mg or 300 mg twice daily for 14 days in patients at risk of aspergillosis (mainly patients with malignant neoplasms of lymphatic or haematopoietic tissue), the observed pharmacokinetic characteristics of rapid and consistent absorption, accumulation and non-linear pharmacokinetics were in agreement with those observed in healthy subjects.
Slovenian: Med 14-dnevno peroralno uporabo 200 mg ali 300 mg dvakrat na dan pri bolnikih, ogroženih z aspergilozo (v glavnem bolnikih z malignimi novotvorbami limfatičnega ali hematopoetskega tkiva), so se opazovane farmakokinetične značilnosti, hitra in konstantna absorpcija, kopičenje in nelinearna farmakokinetika, ujemale s tistimi, opazovanimi pri zdravih preskušancih.
English: In the pre and postnatal development study in rats at exposures lower than those obtained in humans with therapeutic doses, voriconazole prolonged the duration of gestation and labour and produced dystocia with consequent maternal mortality and reduced perinatal survival of pups.
Slovenian: V študijah pre- in postnatalnega razvoja pri podganah je vorikonazol ob izpostavljenosti, manjši kot je pri ljudeh dosežena s terapevtskimi odmerki, podaljšal gestacijo in porod ter povzročil distocijo s posledično maternalno umrljivostjo in zmanjšanim perinatalnim preživetjem mladičev.
English: 3 In clinical studies, response to voriconazole in C. krusei infections was similar to C. albicans, C.
Slovenian: 3 V kliničnih študijah je bil odziv na vorikonazol pri okužbah s C. krusei podoben kot pri C. albicans, C.
English: Digoxin (0.25 mg QD) [P-gp substrate]
Slovenian: digoksin (0.25 mg QD) [P-gp substrate]
English: Inhibitors or inducers of these isoenzymes may increase or decrease voriconazole plasma concentrations, respectively, and there is potential for voriconazole to increase the plasma concentrations of substances metabolised by these CYP450 isoenzymes.
Slovenian: Inhibitorji ali induktorji teh izoencimov lahko zvečajo oziroma zmanjšajo koncentracijo vorikonazola v plazmi, obstaja pa tudi možnost, da vorikonazol zveča plazemsko koncentracijo snovi, ki se presnavljajo preko teh izoencimov CYP450.
English: Do not use this medicine after the expiry date which is stated on the label after EXP.
Slovenian: Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na ovojnini za 'Uporabno do:'.
English: The efficacy and survival benefit of voriconazole versus conventional amphotericin B in the primary treatment of acute invasive aspergillosis was demonstrated in an open, randomised, multicentre study in 277 immunocompromised patients treated for 12 weeks.
Slovenian: Učinkovitost in korist glede preživetja sta bili za vorikonazol v primerjavi s konvencionalnim amfotericinom B pri primarnem zdravljenju akutne invazivne aspergiloze dokazani v odprti, randomizirani, multicentrični raziskavi 277 imunsko oslabelih bolnikov, zdravljenih 12 tednov.
English: In a secondary analysis, which utilised DRC assessments at the latest evaluable time point (EOT, or 2, 6, or 12 weeks after EOT) voriconazole and the regimen of amphotericin B followed by fluconazole had successful response rates of 65 % and 71 %, respectively.
Slovenian: V sekundarni analizi, ki je uporabljala oceno OPP na najpoznejši ocenljivi časovni točki (konec terapije ali 2, 6 ali 12 tednov po koncu terapije), je bil delež uspešnega odziva z vorikonazolom 65 %, s shemo amfotericin B/flukonazol pa 71 %.
English: Patients with renal failure were excluded from this study.
Slovenian: Iz študije so bili izključeni bolniki z odpovedjo ledvic.
English: The ERG measures electrical currents in the retina.
Slovenian: ERG meri električne tokove v mrežnici.
English: Not for bolus injection.
Slovenian: Ni primerno za bolusno injekcijo.
English: In children experiencing photoaging injuries such as lentigines or ephelides, sun avoidance and dermatologic follow-up are recommended even after treatment discontinuation.
Slovenian: Pri otrocih, pri katerih se zaradi svetlobe pojavljajo starostne poškodbe na koži, kot so lentigo ali efelide, je priporočljivo izogibanje soncu in kontrolni pregledi pri dermatologu, tudi po prekinitvi zdravljenja.
English: Hepatic function should be monitored in both children and adults.
Slovenian: Delovanje jeter je treba nadzirati tako pri otrocih kot pri odraslih.
English: Proven or probable IFIs developed in 7.5% (3/40) of patients during the first year after HSCT, including one candidemia, one scedosporiosis (both relapses of prior IFI), and one zygomycosis.
Slovenian: V prvem letu po HSCT se je dokazana ali verjetna IGO pojavila pri 7,5 % (3/40) bolnikov, vključno z enim primerom kandidemije, enim primerom scedosporioze (oba sta bila ponovitev predhodne IGO) in enim primerom zigomikoze.
English: Voriconazole Hikma is presented in packs of 1 or 5 glass vials as a powder for solution for infusion.
Slovenian: Vorikonazol Hikma je na voljo v pakiranjih po 1 ali 5 steklenih vial v obliki praška za raztopino za infundiranje.
English: 30 ml clear Type I glass vial closed with a chlorobutyl rubber stopper and sealed with an aluminium flip off seal with a red plastic matte top button.
Slovenian: 30 ml viala, izdelana iz stekla tipa I, zaprta z gumijastim zamaškom iz klorobutilne gume in zapečatena z aluminijasto dvižno zaporko z mat rdečim vrhnjim gumbom iz plastike.
English: The majority of patients receiving voriconazole treatment of the above mentioned rare infections were intolerant of, or refractory to, prior antifungal therapy.
Slovenian: Večina bolnikov, ki so bili zdravljeni z vorikonazolom zaradi omenjenih redkih okužb, ni prenašala prejšnjega antimikotičnega zdravljenja ali je bila zanj odporna.
English: If you have liver disease, your doctor may prescribe a lower dose of Voriconazole Hikma.
Slovenian: Če imate bolezen jeter, vam bo vaš zdravnik morda predpisal manjši odmerek zdravila Vorikonazol Hikma .
English: 2 In clinical studies, response to voriconazole in patients with C glabrata infections was 21% lower compared to C. albicans, C. parapsilosis and C. tropicalis.
Slovenian: 2 V kliničnih študijah je bil odziv na vorikonazol pri bolnikih z okužbami s C. glabrata za 21 % manjši kot pri C. albicans, C. parapsilosis in C. tropicalis.
English: The major metabolite of voriconazole is the N-oxide, which accounts for 72 % of the circulating radiolabelled metabolites in plasma.
Slovenian: Glavni presnovek vorikonazola je N-oksid; na njegov račun gre 72 % radioaktivno označenih presnovkov, ki krožijo v plazmi.
English: Voriconazole Hikma may cause blurring of vision or uncomfortable sensitivity to light.
Slovenian: Zdravilo Vorikonazol Hikma lahko povzroči zamegljen vid ali neprijetno občutljivost na svetlobo.
English: Scedosporium and Fusarium infections Voriconazole was shown to be effective against the following rare fungal pathogens:
Slovenian: Okužbe s Scedosporium in Fusarium Dokazano je bilo, da je vorikonazol učinkovit proti naslednjim redkim glivičnim patogenom:
English: Instances of hepatic reactions were noted to occur primarily in patients with serious underlying medical conditions (predominantly haematological malignancy).
Slovenian: Primere jetrnih reakcij so opažali predvsem pri bolnikih s hudimi že obstoječimi boleznimi (zlasti hematološkimi malignomi).
English: The compatibility of voriconazole with diluents other than described above or in section 6.2 is unknown.
Slovenian: Združljivost zdravila Vorikonazol Hikma z drugimi tekočinami razen zgoraj naštetih ali omenjenih v poglavju 6.2 ni znana.
English: • Concomitant medicinal product that is known to prolong QTc interval.
Slovenian: • sočasno zdravljenje z zdravili, ki podaljšujejo interval QTc.