FrancophonIA/ELRC3.0 huggingface dataset:
English: If using an intravenous line, follow the injection with an intravenous flush of 5 mL to 15 mL of sterile sodium chloride 9 mg/mL (0.9%) solution for injection to ensure full delivery of the dose.
Slovenian: Pri uporabi intravenskega kanala je po injiciranju treba opraviti intravenozno spiranje s 5 ml do 15 ml sterilne raztopine natrijevega klorida 9 mg/ml (0,9 %) za injiciranje, s čimer se zagotovi injiciranje celotnega odmerka.
English: Please refer to the SmPC {SmPC should be included in the box}.
Slovenian: Glejte SmPC {SmPC mora biti priložen v pakiranju}.
English: Due to the small quantity of flutemetamol (18F) in each dose, overdose is not expected to result in pharmacological effects.
Slovenian: Zaradi majhne količine flutemetamola (18F) v vsakem odmerku, ni pričakovati, da bi prekomeren odmerek imel farmakološke učinke.
English: 185 MBq the typical radiation dose to the target organ (brain) is 2.0 mGy.
Slovenian: Za odmerjeno aktivnost 185 MBq je značilen odmerek sevanja za ciljni organ (možgani) 2,0 mGy.
English: The adult effective dose resulting from the administration of a maximal recommended activity of 185 MBq dose for an adult weighing 70 kg is approximately 5.9 mSv.
Slovenian: Učinkoviti odmerek pri odraslem po dajanju odmerka največje priporočene aktivnosti 185 MBq za odraslo osebo, ki tehta 70 kg, je približno 5,9 mSv.
English: The estimated absorbed radiation doses for adults following intravenous injection of VIZAMYL are shown in Table 2.
Slovenian: Ocenjen absorbiran odmerek sevanja pri odraslih po intravenskem injiciranju zdravila VIZAMYL je prikazan v preglednici 2.
English: What VIZAMYL is and what it is used for
Slovenian: Kaj je zdravilo VIZAMYL in za kaj ga uporabljamo
English: Sensitivity and specificity to estimate β-amyloid deposition of flutemetamol (18F) was further investigated in one additional study, in which a different set of 5 electronically-trained blinded readers interpreted images from the same 68 patients followed to autopsy in the pivotal study.
Slovenian: Občutljivost in specifičnost za oceno nalaganja flutemetamola (18F) v β-amiloidnih lehah sta bili nadalje preučeni v eni dodatni študiji, v kateri je druga skupina slepo izbranih 5 odčitovalcev, ki so imeli usposabljanje v elektronski obliki, interpretiralo posnetke istih 68 bolnikov, pri katerih je bila v ključni študiji opravljena obdukcija.
English: Brain uptake and distribution of flutemetamol (18F) were not evaluated in a specific study aimed to evaluate pharmacodynamics.
Slovenian: Možgansko privzemanje in porazdelitev flutemetamola (18F) nista bila ovrednoteni v posebnih študijah z namenom ocenjevanja farmakodinamike.
English: It is strongly recommended to review MR or CT images when available to aid interpretation of the VIZAMYL image, especially when atrophy is suspected.
Slovenian: Zelo priporočljivo je, da kot pomoč pri interpretaciji posnetka z uporabo zdravila VIZAMYL pregledate slike MR ali CT, če jih imate na voljo, še zlasti ko obstaja sum na atrofijo.
English: A negative scan indicates sparse or no plaques, which is not consistent with a diagnosis of AD. For the limitations in the interpretation of a positive scan, see sections 4.4 and 5.1.
Slovenian: Negativen rezultat preiskave kaže na redke ali odsotne lehe, kar se ne ujema z diagnozo AB. Za omejitve pri interpretaciji pozitivnega rezultata preiskave glejte poglavji 4.4 in 5.1. 4.2 Odmerjanje in način uporabe
English: This radiopharmaceutical will deliver low amounts of ionising radiation, which is associated with very low risk of cancer and hereditary abnormalities (passing on faulty genes).
Slovenian: S tem radiofarmakom prejmete majhne količine ionizirajočega sevanja, ki je povezano z zelo majhnim tveganjem za razvoj raka in dednih nepravilnosti (tj. genetskih bolezni).
English: Elimination and half-Life Flutemetamol (18F) is rapidly cleared from circulation (through the intestinal and urinary tracts).
Slovenian: Izločanje in razpolovni čas Flutemetamol (18F) se hitro odstrani iz krvnega obtoka (skozi prebavni in sečni trakt).
English: This medicinal product contains up to 41 mg (or 1.8 mmol) sodium per dose,equivalent to 2 % of the WHO recommended maximum daily intake of 2 g sodium for an adult.
Slovenian: To zdravilo vsebuje do 41 mg (1,8 mmol) natrija na odmerek, kar je enako 2 % največjega dnevnega vnosa natrija za odrasle osebe, ki ga priporoča SZO in znaša 2 g..
English: The solution should then be withdrawn via the stopper, using either a single-dose syringe fitted with suitable protective shielding and a disposable sterile needle, or an authorised automated application system.
Slovenian: Vial ne smete odpreti, dokler ne razkužite zamaška, raztopino pa morate odvzeti prek zamaška z enoodmerno injekcijsko brizgo, opremljeno z ustrezno zaščito in sterilno iglo za enkratno uporabo, ali z uporabo odobrenega avtomatskega sistema apliciranja.
English: There is no relevant use of VIZAMYL in the paediatric population.
Slovenian: Zdravilo VIZAMYL ni namenjeno za uporabo pri pediatrični populaciji.
English: A positive scan does not independently establish a diagnosis of AD or other cognitive disorder since neuritic plaque deposition in grey matter may be present in asymptomatic elderly patients and some neurodegenerative dementias (Alzheimer's disease, but also Lewy body dementia and Parkinson's disease dementia).
Slovenian: Pozitiven rezultat ocene posnetka sam po sebi ne postavlja diagnoze AB ali druge kognitivne okvare, saj je nastajanje nevritičnih leh v sivi možganovini lahko prisotno pri asimptomatskih starejših osebah in osebah z nekaterimi nevrodegenerativnimi demencami (Alzheimerjeva bolezen, demenca z Lewyjevimi telesci, demenca pri Parkinsonovi bolezni).
English: Read the package leaflet before use.
Slovenian: Pred uporabo natančno preberite priloženo navodilo!
English: Key: Grey matter - f frontal and ac anterior cingulate, pc posterior cingulate and precuneus, lt lateral temporal, tp temporo-parietal and in insula and and s striatum.
Slovenian: Gesla: siva možganovina - f frontalni in ac anteriorni cingulatni, pc posterioni cingulati in prekuneusni, lt stranski temporalni , tp temporo-parietalni in in insula in s striatum.
English: Signal will not be completely absent in grey matter regions of the images, as white matter binding in adjacent regions will bleed into the grey matter regions due to PET partial volume resolution effects.
Slovenian: Signal ne bo popolnoma odsoten v območjih sive možganovine na posnetkih, saj se bo bela možganovina, ki je vezana s sosednjimi območji, zlila z območji sive možganovine, zaradi delnih prostorninskih učinkov ločljivosti PET.
English: The injection of flutemetamol (18F) must be intravenous in order to avoid irradiation as a result of local extravasation, as well as imaging artefacts.
Slovenian: Injiciranje flutemetamola (18F) mora biti intravensko, da se prepreči obsevanje zaradi lokalnega izliva in artefakte pri slikanju.
English: VIZAMYL should be used by, or under the control of, physicians who are qualified by specific training and experienced in the safe use and handling of radionuclides, and whose experience and training have been approved by the appropriate government agency authorised to license the use of radiopharmaceuticals.
Slovenian: Zdravilo VIZAMYL lahko uporabljajo zdravniki, ki so posebej usposobljeni in izkušeni pri varni uporabi in ravnanju z radionuklidi ter katerih izkušnje in usposabljanje je potrdil pristojni upravni organ za podeljevanje licenc za uporabo radiofarmakov, ali osebe pod nadzorom takih zdravnikov.
English: Activity: 400 MBq/mL at {hh:mm} {Time Zone} on {dd-mm-yyyy} Activity: YYYY MBq at hh:mm {Time Zone} dd-mm-yyyy
Slovenian: Aktivnost: 400 MBq/ml ob {hh:mm} {časovni pas} dne {dd-mm-llll} Aktivnost: LLLL MBq v hh:mm {časovni pas} dd-mm-llll
English: • The material should include VIZAMYL PET demonstration cases with correct PET scan interpretation by an experienced reader; VIZAMYL-PET scans for self-assessment; and a selfqualification procedure to be offered to each trainee.
Slovenian: • Gradivo mora vsebovati primere posnetkov PET z zdravilom VIZAMYL in pravilno interpretacijo izkušenega odčitovalca; posnetke PET z zdravilom VIZAMYL za samooceno in postopek samokvalifikacije za vsakega udeleženca usposabljanja.
English: Axial view (first row), sagittal view (second row) and coronal view (third row) are displayed.
Slovenian: Prikazani so aksialni pogled (prva vrstica), sagitalni pogled (druga vrstica) in koronalni pogled (tretja vrstica).
English: The patient's head should be tilted so that the anterior commissure-posterior commissure (ACPC) plane is at right angles to the bore-axis of the PET scanner with the head positioned in a suitable head support.
Slovenian: Glava bolnika mora biti nagnjena, tako da je ravnina sprednje komisure - zadnje komisure, (ravnina AC-PC), pravokotna na os odprtine PET skenerja, pri tem pa mora biti glava nameščena na ustrezni opori za glavo.
English: VIZAMYL contains a maximum of 41 mg of sodium (main component of cooking/table salt) in each dose.
Slovenian: Zdravilo VIZAMYL vsebuje največ 41 mg natrija (glavne sestavine kuhinjske soli) na odmerek.
English: Careful consideration of the benefit risk ratio in these patients is required since an increased radiation exposure is possible.
Slovenian: Pri teh bolnikih je treba skrbno premisliti o razmerju med koristmi in tveganji, saj je lahko izpostavljenost sevanju večja.
English: You must stop breast-feeding for 24 hours after the injection.
Slovenian: Z dojenjem morate prenehati za 24 ur po injiciranju.
English: 400 MBq at reference time.
Slovenian: YYYY MBq na referenčni čas.
English: NAME OF THE MEDICINAL PRODUCT VIZAMYL 400 MBq/mL solution for injection
Slovenian: IME ZDRAVILA VIZAMYL 400 MBq/ml raztopina za injiciranje
English: In vivo, quantitative correlation was assessed in end-of-life patients between flutemetamol (18F) uptake in cortical grey matter and the total β-amyloid burden in autopsied samples using 4G8 anti-amyloid antibody that stains β-amyloid found in both neuritic and diffuse plaques.
Slovenian: In vivo je bila pri bolnikih ob koncu življenja ocenjena kvantitativna korelacija med privzemom flutemetamola (18F) v kortikalno sivo možganovino in celokupnim β-amiloidnim bremenom v vzorcih odvzetih z avtopsijo, z uporabo 4G8 protitelesa proti amiloidu, ki obarva β-amiloid v obeh, nevritičnih in difuznih lehah.
English: For an administered activity of 185 MBq the typical radiation doses delivered to the critical organs, gallbladder, urinary bladder wall, upper large intestine wall, lower large intestine wall, small intestine and liver are 53.1 mGy, 26.8 mGy, 21.6 mGy, 7.8 mGy, 18.9 mGy and 10.5 mGy, respectively.
Slovenian: Za odmerjeno aktivnost 185 MBq so značilni odmerki sevanja za kritične organe, žolčnik, sečni mehur, steno zgornjega debelega črevesa, steno spodnjega debelega črevesa, tankega črevesa in jeter 53,1 mGy, 26,8 mGy, 21,6 mGy, 7,8 mGy, 18,9 mGy in 10,5 mGy, v istem vrstnem redu.
English: Osteogenic cells Ovaries
Slovenian: Mišice osteogene celice
English: Flutemetamol (18F) is distributed throughout the body within several minutes of injection.
Slovenian: Flutemetamol (18F) se v nekaj minutah po injiciranju porazdeli po celem telesu.
English: Vial No: xxx
Slovenian: Št. viale: xxx
English: Common - may affect up to 1 in 10 people looking flushed increased blood pressure
Slovenian: Drugi neželeni učinki vključujejo Pogosti - pojavijo se lahko pri največ 1 od 10 bolnikov zardel izgled, zvišan krvni tlak.
English: Volume: xx.x mL
Slovenian: Prostornina: xx,x ml
English: In a longitudinal study, 232 patients clinically diagnosed with amnestic mild cognitive impairment (aMCI), underwent baseline flutemetamol (18F) PET scans, and were followed for 36 months to evaluate the relationship between flutemetamol (18F) imaging and changes in diagnostic status.
Slovenian: V longitudinalni študiji je 232 bolnikov s klinično diagnozo amnestičnega blagega upada kognitivnih sposobnosti (aMCI - amnestic mild cognitive impairment) opravilo osnovno slikanje PET s flutemetamolom (18F), ti so bili nato spremljani 36 mesecev zaradi ocene povezave posnetkov s flutemetamolom (18F) in sprememb statusa diagnoze.
English: The reader should compare the cortical grey matter signal intensity to the maximum white matter signal intensity.
Slovenian: Odčitovalec mora primerjati intenzivnost signalov kortikalne sive možganovine z največjo intenziteto signalov bele možganovine.
English: See special handling precautions in section 6.6.
Slovenian: Glejte posebne varnostne ukrepe za rokovanje z zdravilom v poglavju 6.6.
English: Healthy controls show low levels of flutemetamol (18F) retention in cerebral cortex.
Slovenian: Zdrave kontrolne osebe kažejo nizke ravni zadržanega flutemetamola (18F) v cerebralni skorji.
English: Administration of VIZAMYL and conduct of the procedure VIZAMYL is given as an injection into your vein (intravenous injection) followed by a flush of sodium chloride solution to ensure full delivery of the dose.
Slovenian: Odmerjanje zdravila VIZAMYL in izvajanje postopka Zdravilo VIZAMYL se daje z injekcijo v veno (intravensko injiciranje), čemur sledi spiranje z raztopino natrijevega klorida, kar pomaga zagotoviti, da prejmete cel odmerek.
English: back pain feeling hot or cold increased breathing rate pain at the injection site heart pounding (palpitations) pain in muscles or bones shaking movements (tremor) puffy and swollen skin fever over breathing (hyperventilation) change in the way you taste things a spinning feeling (vertigo) reduced sense of touch or sensation feeling tired or weak inability to get or maintain an erection indigestion, stomach ache or sore mouth vomiting decreased feeling or sensitivity especially in your skin or your face increase in “blood lactate dehydrogenase” or “neutrophils” in blood tests skin tightness
Slovenian: razbijanje srca (palpitacije), bolečine v mišicah ali kosteh, tresenje (tremor), zabuhla ali otečena koža, povišana telesna temperatura, čezmerno dihanje (hiperventilacija), spremenjen okus, občutek vrtenja (vrtoglavica), zmanjšan občutek za dotik ali zmanjšana občutljivost čutil, utrujenost ali šibkost, nezmožnost erekcije ali ohranjanja erekcije, prebavne težave, bolečine v trebuhu ali vneta usta, bruhanje, zmanjšana občutljivost ali preobčutljivost, še posebej na koži ali obrazu, zvišana količina laktat-dehidrogenaze v krvi ali nevtrofilcev pri krvnih testih, občutek, da vas koža veže.
English: Axial (a), Sagittal (b) and coronal (c) views of a negative and positive flutemetamol (18F)
Slovenian: Aksialni (a), sagitalni (b) in koronalni (c) pogledi negativne in pozitivne slike z flutemetamolom (18F) (levo oziroma desno).
English: Data suggest that flutemetamol (18F) is able to label cored and diffuse amyloid β deposits and neuritic plaques.
Slovenian: Podatki kažejo, da lahko flutemetamol (18F) označi združene in difuzne βamiloidne depozite in nevritične lehe.
English: Non-clinical data reveal no special hazard for humans based on conventional studies of safety pharmacology and repeated dose toxicity.
Slovenian: Neklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti pri ponavljajočih se odmerkih, ne kažejo posebnega tveganja za človeka.
English: Flutemetamol (18F) must not be diluted.
Slovenian: Flutemetamola (18F) ne smete redčiti.
English: VIZAMYL contains alcohol (ethanol) and sodium VIZAMYL contains alcohol (ethanol).
Slovenian: Zdravilo VIZAMYL vsebuje alkohol (etanol) in natrij Zdravilo VIZAMYL vsebuje alkohol (etanol).
English: No dose adjustment is recommended based on age.
Slovenian: Ni priporočil glede prilagoditev odmerka pri starejših.
English: Lot: Vial No: xxx
Slovenian: Lot: Št. viale: xxx
English: MARKETING AUTHORISATION NUMBER(S) EU/1/14/941/001
Slovenian: ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/14/941/001
English: The images should be viewed in a systematic manner (Figure 1) starting at the level of pons (p) and scrolling up through The frontal lobes and anterior cingulate (f, ac, axial review) Posterior cingulate and precuneus (pc, sagittal review) Temporo-parietal aspects including Insula (in, axial review and tp-in, coronal review) Lateral temporal lobes (lt, axial review) Striatal region (s, axial review)
Slovenian: Posnetke je treba pregledati sistematično (slika 1) in začeti na višini ponsa (p) ter se pomikati navzgor po čelnih režnjih in anteriornem cingulatnem korteksu (f, ac, aksialni pregled); posteriornem cingulatnem kortes in prekuneus (pc, sagitalni pregled); temporo-parietalnem pogledu vključno z insulo (in, aksialni pregled in tp-in, koronalni pregled); striatnem območju (s, aksialni pregled).
English: Summary of the safety profile The overall safety profile of VIZAMYL is based on data from its administrations to 831 subjects.
Slovenian: Celovit varnostni profil zdravila VIZAMYL temelji na podatkih 831 oseb, ki so prejele zdravilo.
English: In vitro binding studies have not shown interference of flutemetamol (18F) binding to β-amyloid plaques in the presence of other common medicinal products taken by AD patients.
Slovenian: Študije vezave in vitro niso prikazale motenj vezave flutemetamola (18F) na β-amiloidne lehe v prisotnosti drugih pogostih zdravil, ki jih jemljejo bolniki z AB.
English: As a result of the manufacturing process some vials are distributed with punctured rubber stoppers.
Slovenian: Zaradi razlik pri proizvodnem procesu obstaja možnost, da imajo viale nekaterih serij zdravila prebodene gumijaste zamaške.
English: Dizziness Headache Hypoaesthesia Hypotonia Dysgeusia Tremor
Slovenian: Bolezni živčevja omotica glavobol hipestezija hipotonija disgevzija tresavica
English: The negative images show a sulcal/gyral white matter pattern.
Slovenian: Negativni posnetki kažejo vzorec sulkusov/girusov bele možganovine.
English: What VIZAMYL looks like and contents of the pack VIZAMYL is a clear, colourless to slightly yellow solution for injection.
Slovenian: Izgled zdravila VIZAMYL in vsebina pakiranja Zdravilo VIZAMYL je čista, brezbarvna do rahlo rumena raztopina za injiciranje.
English: You must inform the nuclear medicine doctor before you are given VIZAMYL if there is a possibility you might be pregnant, if you have missed your period or if you are breast-feeding.
Slovenian: Preden prejmete zdravilo, morate zdravnika nuklearne medicine obvestiti, če obstaja možnost, da ste noseči, če ste imeli izpad mesečnega perila ali če dojite.
English: What you need to know before VIZAMYL is used
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo VIZAMYL
English: A region is considered positive (abnormal) if the tracer signal in cortical regions appears high (i.e., approximately at the same or higher signal intensity as adjacent white matter and greater than the grey matter-rich regions of the cerebellum).
Slovenian: Območje ima pozitiven (nenormalen) vzorec, če je signal označevalnega sredstva v kortikalnih območjih na videz močan (npr. približno enake ali višje intenzivnosti kot signal sosednje bele možganovine in večji kot v območjih sive možganovine v bogatih območjih malih možganov).
English: No animal studies have been conducted to investigate the reproductive effects of flutemetamol (18F) (see section 5.3).
Slovenian: Študij na živalih, s katerimi bi preučili učinke flutemetamola (18F) na razmnoževanje, niso izvedli (glejte poglavje 5.3).
English: Serious side effects Tell your doctor straight away, if you notice any of the following, as you may need urgent medical treatment: Allergic reactions - the signs may include swelling of your face or eyes, having pale, itchy or tight skin or having a rash, feeling short of breath, tightness in the chest, irritation in your throat or being sick.
Slovenian: Resni neželeni učinki Če opazite kateri koli neželeni učinek, takoj obvestite zdravnika, morda boste potrebovali nujno zdravniško pomoč: Alergijske reakcije - znaki vključujejo otekanje obraza ali oči, bleda, srbeča ali napeta koža ali izpuščaj, težave z dihanjem, stiskanje v prsnem košu, draženje v grlu ali občutek slabosti.
English: Tell your doctor straight away if you notice any of the signs above.
Slovenian: Če opazite katerega koli od zgornjih znakov, nemudoma obvestite zdravnika.
English: After 20 minutes approximately 20 % of the active compound flutemetamol (18F) remains in the circulation,
Slovenian: Po 20 minutah ostane v krvnem obtoku približno 20 % aktivne učinkovine flutemetamol (18F) v 180 minutah pa se vsebnost zniža na 10 %.
English: The following adverse reactions may occur as symptoms and signs of a hypersensitivity reaction to VIZAMYL or any of its excipients (see section 6.1): eye/face swelling, pallor, dyspnoea, throat irritation, vomiting, rash, pruritus, skin tightness, chest tightness (see also section 4.4).
Slovenian: Naslednji neželeni učinki se lahko pojavijo kot simptomi ali znaki preobčutljivostne reakcije na zdravilo VIZAMYL ali katero koli pomožno snov (glejte poglavje 6.1): zatekanje oči/obraza, bledica, dispneja, draženje grla, bruhanje, izpuščaj, pruritus, napetost kože, stiskanje v prsnem košu (glejte tudi poglavje 4.4).
English: The administration of radiopharmaceuticals creates risks for other persons from external radiation or contamination from spills of urine, vomiting etc.
Slovenian: Dajanje radiofarmakov pomeni tveganje za druge osebe zaradi izpostavljenosti zunanjemu sevanju ali kontaminacije zaradi razlitja urina, bruhanja, itd. Previdnostni ukrepi za zaščito pred sevanjem morajo biti v skladu z nacionalnimi predpisi.
English: A region is considered as having a negative (normal) pattern if the tracer signal in cortical regions is low (i.e. distinctly lower signal intensity compared with adjacent white matter and similar in intensity to the grey matter-rich regions of the cerebellum).
Slovenian: Območje ima negativen (normalen) vzorec, če je signal označevalnega sredstva v kortikalnih območjih nizek (npr. jasno nižja intenzivnost signala v primerjavi s signalom sosednje bele možganovine in ima podobno intenzivnost kot signal sive možganovine-bogata območja malih možganov).
English: MARKETING AUTHORISATION NUMBER(S) EU/1/14/941/002
Slovenian: ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/14/941/002
English: Breast-feeding It is not known whether flutemetamol (18F) is excreted in human milk during breast-feeding.
Slovenian: Ni znano, ali se flutemetamol (18F) med dojenjem izloča v materino mleko.
English: VIZAMYL is a radiopharmaceutical medicinal product indicated for Positron Emission Tomography (PET) imaging of β-amyloid neuritic plaque density in the brains of adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) and other causes of cognitive impairment.
Slovenian: Zdravilo VIZAMYL je radiofarmak, indiciran za slikanje gostote β-amiloidnih nevritičnih leh s pozitronsko emisijsko tomografijo (PET) v možganih odraslih bolnikov s kognitivno motnjo, pri katerih se ugotavlja Alzheimerjeva bolezen (AB) in drugi vzroki kognitivne motnje.
English: A PET scan with flutemetamol (18F) should be requested by clinicians experienced in the clinical management of neurodegenerative disorders.
Slovenian: Preiskavo PET s flutemetamolom (18F) mora naročiti zdravnik, ki je usposobljen za klinično obravnavo nevrodegenerativnih bolezni.
English: The in vivo binding of flutemetamol (18F) to other β-amyloid structures or other brain structures or receptors remains unknown.
Slovenian: Vezava flutemetamola (18F) in vivo na druge β-amiloidne strukture ali druge strukture v možganih ostaja nepoznana.
English: At the 36-month follow-up, 81 (35%) converted to clinical AD. Of the 97 aMCI patients who had a positive PET scan and at least one committee assessment, 52 (54%) were classified clinically as converted to clinical AD after 36 months compared to 29 (23%) of 127 who had a negative scan and at least one committee assessment.
Slovenian: V spremljanju po 36 mesecih je 81 (35 %) bolnikov dobilo diagnozo AB. Od 97 bolnikov z diagnozo aMCI, pri katerih je bila PET slika pozitivna in so imeli vsaj eno oceno neodvisne komisije, jih je bilo 52 (54 %) klinično ocenjenih s spremenjeno diagnozo v AB po 36 mesecih, v primerjavi z 29 (23 %) od 127 bolnikov, pri katerih je bila slika negativna in so imeli vsaj eno oceno neodvisne komisije.