FrancophonIA/ELRC3.0 huggingface dataset:
English: Local treatment guidelines regarding the use of antibiotic prophylaxis around orthopaedic surgery should
Slovenian: Upoštevati je treba lokalne smernice zdravljenja glede uporabe antibiotične profilakse pri ortopedskem
English: In such situations, your surgeon will be informed and might have to select an alternative treatment for
Slovenian: V teh primerih vas bo vaš kirurg o tem obvestil in morda za vas izbral drugo zdravljenje.
English: Controlled physiotherapy, including early mobilisation, range-of-motion exercises, and partial weightbearing is recommended as soon as possible to promote graft maturation and to reduce the risk of postoperative thromboembolic events and joint stiffness.
Slovenian: Takoj ko je mogoče, se priporoča fizioterapija, vključno z zgodnjo mobilizacijo, vajami za izboljšanje gibljivosti in delnim obremenjevanjem, da se pospeši zorenje vsadka in zmanjša tveganje trombemboličnih dogodkov in otrdelosti sklepa po operaciji.
English: You will need to have two surgical procedures to receive this treatment:
Slovenian: V okviru tega zdravljenja boste imeli dva kirurška posega:
English: Patients with local inflammations or active infections in the bone, joint, and surrounding soft tissue should be temporarily deferred until documented recovery.
Slovenian: Pri bolnikih z lokalnim vnetjem ali aktivno okužbo kosti, sklepa ali okoliškega mehkega tkiva je treba postopek začasno odložiti, dokler bolnik ne okreva.
English: Limited clinical data on exposed pregnancies are available.
Slovenian: Podatki o uporabi pri nosečnicah so omejeni.
English: Store shipping box in an area below 37°C.
Slovenian: Transportno škatlo shranjujte pri temperaturi do 37 °C.
English: A fibrin sealant is a type of glue that is made from human blood-clotting
Slovenian: Fibrinsko lepilo je vrsta lepila, izdelanega iz človeških beljakovin, ki povzročajo
English: Risk factors for graft delamination can include but are not limited to poor patient selection, poor adherence to recommended surgical technique, failure to address concomitant pathologies, poor compliance with the rehabilitation protocol or post-operative trauma to the knee.
Slovenian: Dejavniki tveganja za razslojitev presadka lahko med drugim vključujejo neustrezno izbiro bolnika, neupoštevanje priporočene kirurške tehnike, neobravnavanje sočasnih patologij, neupoštevanje rehabilitacijskega protokola ali poškodbo kolena po operaciji.
English: • are allergic to any of the ingredients of MACI (listed in section 6), or porcine products (derived from pigs), bovine serum (a protein derived from cows) or gentamicin (an antibiotic)
Slovenian: • če ste alergični na katero koli sestavino zdravila MACI (navedeno v poglavju 6) ali na izdelke pridobljene iz prašičev, goveji serum (beljakovina, pridobljena iz krav) ali gentamicin
English: While oral use of pain medication is recommended for post-surgical pain relief, intra-articular administration of analgesics is not recommended as studies have shown adverse effects on articular cartilage and chondrocytes with exposure.
Slovenian: Medtem ko se za lajšanje bolečine po operaciji priporočajo peroralni analgetiki, se intraartikularno dajanje analgetikov ne priporoča, saj so študije pokazale neželene učinke na sklepni hrustanec in hondrocite.
English: Genzyme Biosurgery ApS, Oliefabriksvej 51B, DK-2770 Kastrup, Denmark This leaflet was last revised in MM/YYYY
Slovenian: Izdelovalec Genzyme Biosurgery ApS, Oliefabriksvej 51B, DK-2770 Kastrup, Danska
English: The safe use of MACI has not been demonstrated during pregnancy or breast-feeding.
Slovenian: Varnost uporabe zdravila MACI med nosečnostjo ali dojenjem ni bila dokazana.
English: The educational pack for healthcare professionals shall contain the following components:
Slovenian: Izbraževalni paket za zdravstveno osebje mora vsebovati naslednje:
English: In the pivotal study of MACI, patients were excluded if they had a history of osteoarthritis (Kellgren-Lawrence Grade 3 or 4) in the target knee, or concomitant inflammatory disease.
Slovenian: V osrednji študiji z zdravilom MACI so bili bolniki izključeni, če so imeli v anamnezi osteoartritis (3. ali 4. stopnje po lestvici Kellgren-Lawrence) v ciljnem kolenu ali sočasno vnetno bolezen.
English: Patients may require debridement of the hypertrophic tissue
Slovenian: Bolniki bodo morda potrebovali presaditev hipertrofičnega tkiva z artroskopskim postopkom.
English: MACI was superior compared to microfracture regarding the improvement of pain and function according to the KOOS scale (Knee Injury and Osteoarthritis Outcome Score).
Slovenian: Zdravilo MACI je bilo v primerjavi s postopkom mikrofrakture boljše v smislu izboljšanja bolečine in funkcije po lestvici KOOS (angl. Knee Injury and Osteoarthritis Outcome Score - merjenje izida ob poškodbi kolena in osteoartritisu).
English: When you receive MACI, you may experience side effects soon after the implantation.
Slovenian: Ko boste prejeli zdravilo MACI, boste morda kmalu po vsaditvi začutili neželene učinke.
English: SPECIAL STORAGE CONDITIONS Do not refrigerate or freeze.
Slovenian: POSEBNA NAVODILA ZA SHRANJEVANJE Ne shranjujte v hladilniku ali zamrzujte.
English: The use of MACI in elderly with generalised degeneration of the cartilage or osteoarthritis is not recommended.
Slovenian: Uporaba zdravila MACI pri starejših bolnikih z generalizirano degeneracijo hrustanca ali osteoartritisom ni priporočljiva.
English: However as MACI will be implanted using invasive surgical techniques, a decision must be made whether to discontinue breastfeeding taking into account the benefits of treatment for the woman and the risk to the infant.
Slovenian: Ker pa poteka vsaditev zdravila MACI z uporabo invazivne kirurške tehnike, se je treba odločiti, ali naj mati z dojenjem preneha, pri čemer je treba pretehtati prednosti dojenja za otroka in prednosti zdravljenja za mater.
English: MACI is not recommended in patients with a total menisectomy unless the meniscal deficiency can be addressed with a staged or concurrent meniscal graft.
Slovenian: Zdravila MACI se ne priporoča pri bolnikih s popolno meniscektomijo, razen če je mogoče okvaro meniskusa obravnavati z zaporednim ali sočasnim presadkom meniskusa.
English: MACI is an autologous implant and must only be administered to the patient for whom it was manufactured.
Slovenian: Zdravilo MACI je avtologni vsadek, ki ga lahko dobi le bolnik, za katerega je bil izdelan.
English: Abnormal varus or valgus loading of the tibio-femoral joint may jeopardise the implant and should be addressed with a corrective osteotomy or similar procedure.
Slovenian: Obremenitev tibiofemoralnega sklepa zaradi nenormalnega varusa ali valgusa lahko ogrozi vsadek, zato jo je treba obravnavati s korekcijsko osteotomijo ali podobnim postopkom.
English: There is limited experience with delivery of MACI to the knee via arthroscopy, however, arthroscopic techniques may be used to apply MACI at the discretion of the treating physician.
Slovenian: Izkušnje z vstavitvijo zdravila MACI v koleno z artroskopijo so omejene, vendar pa se po presoji lečečega zdravnika lahko uporabijo artroskopske tehnike za vsaditev zdravila MACI lahko uporabijo.
English: There were no indications of gross inflammatory
Slovenian: Znakov večje vnetne reakcije ni bilo.
English: INFORMATION IN BRAILLE Justification for not including Braille accepted
Slovenian: Sprejeta je utemeljitev, da Braillova pisava ni potrebna
English: • difficulty breathing, chest pain and palpitations • leg swelling, leg pain and redness
Slovenian: • težko dihanje, bolečine v prsih in razbijanje srca (palpitacije), • otekanje noge, bolečina v nogi in rdečica.
English: Dulbecco's Modified Eagles Medium (DMEM; Calcium Chloride anhydrous, Ferric Nitrate.9H2O, Potassium Chloride, Magnesium Sulphate anhydrous, Sodium Chloride, Sodium Bicarbonate, Potassium Phosphate Monobasic.H2O, D-Glucose, L-Arginine.HCl, L-Cystine.2HCl, L-Glutamine, Glycine, L-Histidine.HCl.H2O, L-Isoleucine, L-Leucine, L-Lysine.HCl, L-Methionine, L-Phenylalanine, L-Serine, L-Threonine, L-Tryptophan, L-Tyrosine.2Na.2H2O, L-Valine, D-Calcium Pantothenate, Choline Chloride, Folic Acid, i-Inositol, Niacinamide, Riboflavin, Thiamine.HCl, Pyridoxine.HCl) with 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium (HEPES) adjusted for pH with HCl or NaOH and osmality with NaCl.
Slovenian: Eaglov medij, modificiran po Dulbeccu (DMEM; Dulbecco's Modified Eagles Medium; brezvodni kalcijev klorid, železov nitrat.9H2O, kalijev klorid, brezvodni magnezijev sulfat, natrijev klorid, natrijev bikarbonat, monobazični kalijev fosfat.H2O, D-glukoza, L-arginin.HCl, L-cistin.2HCl, Lglutamin, glicin, L-histidin.HCl.H2O, L-izolevcin, L-levcin, L-lizin.HCl, L-metionin, L-fenilalanin, L
English: The use of MACI is not recommended in patients over 65 years of age who have generalised degeneration of the cartilage or osteoarthritis (disease of the joints with pain and swelling).
Slovenian: Uporaba zdravila MACI se ne priporoča pri bolnikih, starejših od 65 let z generalizirano degeneracijo hrustanca ali osteoartritisom (boleznijo bolečih in oteklih sklepov).
English: Possible side effects
Slovenian: Ti učinki se
English: There were no significant differences observed in the structural markers of cartilage repair between both treatments, as assessed by International Cartilage Repair Society (ICRS) II overall assessment histology scores of biopsies, and MRI defect fill scores.
Slovenian: Značilnih razlik v strukturnih markerjih obnovljenega hrustanca med obema skupinama niso opazili, kar so ocenili s splošnim rezultatom histološkega rezultata biopsij po Mednarodni organizaciji za zdravljenje hrustanca (ICRS II, International Cartilage Repair Society) in rezultatu zapolnjenja okvare na MRI.
English: Missing * KOOS Response Rate: Responder is defined as an improvement of the Knee Injury and Osteoarthritis Outcome Score from baseline of minimal 10 points of a scale of 100.
Slovenian: * Stopnja odziva po lestvici KOOS: Kot odzivni bolnik je opredeljen bolnik z izboljšanjem izida poškodbe kolena in osteoartritisa od izhodiščne vrednosti za vsaj 10 točk na 100-točkovni lestvici.
English: Implantation of MACI is performed using sterile surgical techniques and requires both the preparation of the defect bed and the application of fibrin sealant to the base and rim of the defect in order to secure the implant.
Slovenian: Vsaditev zdravila MACI se izvede s sterilno kirurško tehniko in zahteva pripravo ležišča okvare in uporabo fibrinskih lepil na bazi in robu območja okvare, da se vsadek dobro pritrdi.
English: Given the local nature of the medicinal product, adverse reactions of MACI on pregnancy are not anticipated.
Slovenian: Zaradi lokalne narave zdravila neželenih reakcij zaradi zdravila MACI na nosečnost ne pričakujemo.
English: In rare cases the cell processing facility will not be able to produce MACI from your cells.
Slovenian: V redkih primerih v laboratoriju za obdelavo celic ne bodo uspeli izdelati zdravila MACI iz vaših celic.
English: To create a favourable environment for healing, concomitant pathologies must be addressed prior to or concurrent with implantation of MACI.
Slovenian: Da ustvarite ugodno okolje za celjenje, je treba sočasne patologije obravnavati pred vsaditvijo zdravila MACI ali sočasno.
English: Complications related to knee surgery in general may also include deep vein thrombosis and pulmonary embolism.
Slovenian: Zapleti, na splošno povezani z operacijo kolena, lahko vključujejo globoko vensko trombozo in pljučno embolijo.
English: Complications related to knee surgery in general may include deep vein thrombosis (blood clotting in a deep vein) and pulmonary embolism (blood clotting in the lung due to blockage of a lung artery).
Slovenian: Zapleti, ki so v splošnem povezani z operacijo kolena, lahko vključujejo globoko vensko trombozo (krvne strdke v globokih venah) in pljučni embolizem (krvni strdek v pljučih zaradi zamašitve pljučne arterije).
English: Therefore, it may occur that MACI cannot be delivered.
Slovenian: Zato se lahko zgodi, da zdravila MACI ne bo mogoče
English: A rabbit study demonstrated that at 3 months post-implantation, minimal numbers of inflammatory cells were present in the vicinity of the defect, with variable chondrogenesis.
Slovenian: Študija pri kuncih je dokazala, da je bilo v 3 mesecih po vsaditvi prisotno minimalno število vnetnih celic v bližini okvare s spremenljivo hondrogenezo.
English: The final MACI implant will be sent back to your surgeon.
Slovenian: Končni vsadek zdravila MACI se vrne kirurgu.
English: Thromboprophylaxis should be administered according to local guidelines.
Slovenian: Tromboprofilakso je treba dati v skladu z lokalnimi smernicami.
English: If you notice any of the following, please contact your doctor immediately, since these may be symptoms of blood clotting:
Slovenian: Če opazite katero koli od naslednjih stanj, se nemudoma posvetujte z zdravnikom, saj so lahko to
English: • have severe osteoarthritis of the knee (disease of the joints with pain and swelling)
Slovenian: • če imate hud osteoartritis kolena (bolezen bolečih in oteklih sklepov);
English: • That MACI is an autologous product and should only be administered to the patient that the biopsy was taken from.
Slovenian: • Da je zdravilo MACI avtologni izdelek in da se uporablja le pri bolnikih, ki so jim z biopsijo odvzeli hrustanec.
English: The implantation matrix is trimmed by the treating surgeon to the size and shape of the defect, to ensure the damaged area is completely covered, and implanted cell-side down.
Slovenian: Kirurg obreže matriks za vsaditev na velikost in obliko okvare, pri čemer zagotovi, da je poškodovani predel v celoti prekrit in da je stran z vsajenimi celicami obrnjena navzdol.
English: What MACI looks like and contents of the pack
Slovenian: Izgled zdravila MACI in vsebina pakiranja
English: • Educational material on appropriate follow-up The educational material for surgeons and other healthcare professionals involved in the surgical treatment of patients receiving MACI shall include the following key messages:
Slovenian: • Izobraževalno gradivo o ustreznem postopku spremljanja bolnika Izobraževalno gradivo za kirurge in drugo zdravstveno osebje, ki je odgovorno za kirurško zdravljenje bolnikov z zdravilom MACI, mora vsebovati naslednja ključna sporočila:
English: Characterised viable autologous chondrocytes expanded ex vivo expressing chondrocyte-specific marker genes, seeded onto a CE marked porcine derived Type I/III collagen membrane.
Slovenian: Karakterizirani viabilni avtologni hondrociti, ekspandirani ex vivo, ki izražajo hondrocitsko specifične markerske gene, nacepljeni na kolagensko membrano tipa I/III, pridobljeno iz prašiča, z oznako CE.
English: • Inflammatory arthritis, inflammatory joint disease, or uncorrected congenital blood coagulation
Slovenian: • Vnetni artritis, vnetna bolezen sklepov ali nekorigirane prirojene motnje strjevanja krvi.
English: MACI will be sent back to the surgeon.
Slovenian: Zdravilo MACI bo vrnjeno kirurgu.
English: • If you have any further questions, ask your doctor, surgeon or physical therapist.
Slovenian: • Če imate dodatna vprašanja, se posvetujte z zdravnikom, kirurgom ali fizioterapevtom.
English: • have a known, uncorrected bleeding disorder
Slovenian: • če imate neobravnavano motnjo strjevanja krvi;
English: Cases in which MACI cannot be supplied
Slovenian: Primeri, ko zdravila MACI ni mogoče priskrbeti
English: The minimum amount of time is 6 weeks; however, cells can also be cryopreserved and held in storage for up to 24 months until a surgical date is established.
Slovenian: Najkrajši čas je 6 tednov, vendar pa je mogoče celice z liofilizacijo shraniti do 24 mesecev, dokler se ne določi dan posega.
English: On average this will be 6 weeks, however, cells can also be frozen and held in storage for up to 2 years until a convenient date for surgery is agreed between you and your surgeon.
Slovenian: To povprečno traja 6 tednov, vendar pa je mogoče celice zamrzniti za obdobje do 2 let, dokler se s kirurgom ne dogovorite za ustrezen datum operacije.
English: Typical clinical pharmacokinetic (ADME) studies have not been performed on MACI.
Slovenian: Z zdravilom MACI niso opravili običajnih kliničnih farmakokinetičnih študij (ADME).
English: MACI has been investigated in a parallel, randomised, open-label trial in 144 patients with Outerbridge Grade III or IV focal cartilage defects of the knee of 3-20 cm
Slovenian: Zdravilo MACI so preučili v paralelnem, randomiziranem, odprtem preskušanju s 144 bolniki s fokalno okvaro hrustanca kolena III. ali IV. stopnje po Outerbridgu, velikosti 3-20 cm
English: Your surgeon can explain these to you.
Slovenian: Kirurg vam bo razložil tveganja.
English: • Hypersensitivity to any of the excipients listed in section 6.1, or porcine products, or any residual component carried over from manufacture of MACI, including bovine serum, and gentamicin.
Slovenian: • Preobčutljivost na katero koli pomožno snov, navedeno v poglavju 6.1, pripravke iz prašičev ali preostanke snovi, ki nastanejo v postopku izdelave zdravila MACI, vključno z govejim
English: Medicinal products on “restricted” medical prescription, reserved for use in certain specialised areas (see Annex I: Summary of Product Characteristics, section 4.2).
Slovenian: Zdravilo je namenjeno uporabi samo za določena specialistična zdravljenja (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje
English: This package is enclosed in an outer carton insulated with ambient gel packs.
Slovenian: To pakiranje je spravljeno v zunanjo škatlo, izolirano z gelnimi vložki okoliške temperature.
English: Any spillage or waste material should be disposed as surgical waste material in compliance with local practice.
Slovenian: Razlit ali odpadni material odstranite kot kirurški odpadni material v skladu z lokalno prakso.
English: In a horse study, signs of a minor inflammatory response, characterised by a slight increase in synovial fluid volume and a mild lymphoid accumulation in the synovium, were observed at 3 months.
Slovenian: V študiji s konji so pri 3 mesecih opazili znake manjše vnetne reakcije, za katero je bilo značilno manjše zvišanje količine sinovijske tekočine in blago limfoidno kopičenje v sinoviji.
English: SPECIAL WARNING THAT THE MEDICINAL PRODUCT MUST BE STORED OUT OF THE SIGHT AND REACH OF CHILDREN
Slovenian: POSEBNO OPOZORILO O SHRANJEVANJU ZDRAVILA ZUNAJ DOSEGAIN
English: MACI must only be implanted by surgeons who have been specifically trained for this kind of surgery.
Slovenian: Zdravilo MACI lahko vsadijo le za to vrsto posegov posebej usposobljeni kirurgi.
English: On average this will be 6 weeks, however, cells can also be cryopreserved and held in storage for up to 2 years until a convenient date for surgery is agreed between the patient and surgeon.
Slovenian: To povprečno traja 6 tednov, vendar pa je mogoče celice shraniti z liofilizacijo za obdobje do 2 let, dokler se kirurg in bolnik ne dogovorita za ustrezen dan za operacijo.
English: Each dish is sealed in a gamma-irradiated clear plastic bag.
Slovenian: Vsaka posoda je zatesnjena v prozorni plastični vreči, obsevani z gama žarki.
English: Administration of pain relievers into the joint is not recommended.
Slovenian: Dajanje protibolečinskih blokad v sklepe ni priporočljivo.
English: Dulbecco's Modified Eagles Medium (DMEM) with 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium (HEPES)
Slovenian: Eaglov medij, modificiran po Dulbeccu (DMEM) s 4-(2-hidroksietil)piperazin-1-etansulfonska kislina
English: The timing between the removal of the biopsy and MACI implantation can vary depending on logistical factors in addition to the quality and number of cells obtained from the biopsy.
Slovenian: Časovni razmik med odvzemom biopsije in vsaditvijo zdravila MACI se razlikuje glede na logistične dejavnike in glede na kakovost in število celic, pridobljenih v biopsiji.
English: The implant is an opaque, off-white membrane supplied in 18 ml of colourless solution in a dish.
Slovenian: Vsadek je neprozorna, belkasta membrana, na voljo v 18-mililitrski brezbarvni raztopini v posodici.
English: MACI is supplied in 1 to 2 dishes, which are placed into a 95kPa pouch (outer bag) with absorbent material for transport.
Slovenian: Zdravilo MACI je na voljo v 1 do 2 posodah, ki sta spravljeni v vrečo (zunanja vreča) s 95 kPa z
English: Any unused medicinal product or waste material should be disposed of as surgical waste in accordance with local requirements.
Slovenian: Neuporabljeno zdravilo ali odpadni material zavrzite kot kirurški odpadek v skladu z lokalnimi predpisi.
English: Do not use MACI after the expiry date which is stated on the outer carton and the dish after EXP. Do not refrigerate or freeze.
Slovenian: Zdravila MACI ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na zunanji škatli in posodici poleg oznake EXP.
English: The length of time between your biopsy and the implantation of MACI can vary depending on the procedure date and the quality and number of cells in the biopsy.
Slovenian: Čas med biopsijo in vsaditvijo zdravila MACI se razlikuje glede na datum postopka in kakovost števila celic v biopsiji.
English: MACI is used in adults to repair cartilage defects in your knee joint.
Slovenian: Zdravilo MACI se uporablja pri odraslih za zdravljenje okvar hrustanca v kolenskem sklepu.
English: PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON, OUTER BAG
Slovenian: PODATKI NA ZUNANJI OVOJNINI ZUNANJA ŠKATLA, ZUNANJA VREČA
English: Post-operative haemarthrosis occurs mainly in patients with a predisposition to haemorrhage or poor surgical haemorrhage control.
Slovenian: Pooperativna hemartroza se pojavi predvsem pri bolnikih, nagnjenih h krvavitvam, ali pri neustreznem kirurškem nadzoru krvavitve.
English: Name and address of the manufacturer of the biological active substance Genzyme Biosurgery ApS
Slovenian: Ime in naslov izdelovalca biološke zdravilne učinkovine
English: The surgeon will organise the date for MACI implantation in consultation with the Marketing Authorisation Holder (MAH) or its local representative.
Slovenian: Kirurg bo določil dan za ponovno vsaditev zdravila MACI v dogovoru z imetnikom dovoljenja za promet ali njegovim lokalnim predstavnikom.
English: MACI is indicated for the repair of symptomatic, full-thickness cartilage defects of the knee (grade III and IV of the Modified Outerbridge Scale) of 3-20 cm in skeletally mature adult patients.
Slovenian: Zdravilo MACI je indicirano za popravljanje simptomatskih okvar kolenskega hrustanca po vsej debelini (III. in IV. stopnje Modificirane lestvice Outerbridge, angl. Modified Outerbridge Scale) v pri odraslih bolnikih z zrelim okostjem.
English: If this occurs, the surgeon will advise the patient on the best course of action.
Slovenian: V tem primeru bo kirurg bolniku svetoval najprimernejši nadaljnji potek.
English: Infections and infestations
Slovenian: • okužba,
English: The surgical procedure will have a major impact on your ability to drive and use machines.
Slovenian: Vpliv na sposobnost upravljanja vozil in strojev Kirurški poseg bo bistveno vplival na vašo sposobnost vožnje ali upravljanja strojev.
English: What you need to know before you use MACI Do NOT use MACI if you:
Slovenian: Kaj morate vedeti, preden boste uporabili zdravilo MACI
English: In rare cases the MAH will not be able to produce a MACI implant from the available cells.
Slovenian: V redkih primerih imetnik dovoljenja za promet ne bo uspel izdelati vsadka zdravila MACI iz razpoložljivih celic.
English: When treating trochlear and patellar defects, abnormal patellar tracking must be corrected, prior to or concurrent with MACI implantation.
Slovenian: Pri zdravljenju trohlearnih in patelarnih okvar je treba nenormalno sledenje pogačice popraviti pred vsaditvijo zdravila MACI ali sočasno ob vsaditvi.
English: • currently suffer from inflammatory arthritis or inflammatory joint disease of the knee
Slovenian: • če imate trenutno vnetni artritis ali vnetno bolezen kolenskega sklepa;