FrancophonIA/ELRC3.0 huggingface dataset:
English: • Famotidine
Icelandic: Famotidin
English: • Potassium phosphate
Icelandic: Kalíumfosfat
English: Oral contraceptives ethinylestradiol (EE) (0.03 mg)/ levonorgestrel (LNG) (0.15 mg) single dose/ letermovir (480 mg daily)
Icelandic: Cmax 0,92 (0,84; 1,00) Getnaðarvarnarlyf til inntöku ethinylestradiol (EE) (0,03 mg)/ levonorgestrel (LNG) (0,15 mg) stakur skammtur/ letermovir (480 mg daglega)
English: It is unknown whether dialysis will result in meaningful removal of PREVYMIS from systemic circulation.
Icelandic: Ekki er þekkt hvort himnuskilun fjarlægi PREVYMIS svo nokkru nemi úr blóðrás.
English: Risk of ↓ contraceptive steroids Letermovir may reduce plasma concentrations of other oral contraceptive steroids thereby affecting their efficacy.
Icelandic: Letermovir getur minnkað plasmaþéttni annarra getnaðarvarnarhormóna til inntöku og þannig haft áhrif á verkun þeirra.
English: Intravenous bag materials
Icelandic: Efni í innrennslissettum
English: Both elimination pathways involve active uptake into the hepatocyte through the hepatic uptake transporters OATP1B1/ 3.
Icelandic: Báðar brotthvarfsleiðir fela í sér virka upptöku í lifrarfrumur með þátttöku lifrarupptökupróteinanna OATP1B1/3.
English: Anti-arrhythmic medicinal products amiodarone
Icelandic: Lyf við hjartsláttartruflunum amiodaron
English: HMG-CoA reductase inhibitors atorvastatin (20 mg single dose)/ letermovir (480 mg daily)
Icelandic: HMG-CoA redúktasahemlar atorvastatin (20 mg stakur skammtur)/ letermovir (480 mg daglega)
English: PREVYMIS contains lactose
Icelandic: PREVYMIS inniheldur laktósa
English: The recommended dose of PREVYMIS is 480 mg once a day.
Icelandic: Ráðlagður skammtur af PREVYMIS er 480 mg einu sinni á dag.
English: -Examples of moderate inducers include thioridazine, modafinil, ritonavir, lopinavir, efavirenz and etravirine.
Icelandic: -Dæmi um meðalöfluga virkja eru m.a. thioridazin, modafinil, ritonavir, lopinavir, efavirenz og etravirin.
English: INSTRUCTIONS ON USE
Icelandic: Niðurstöður vantar
English: If PREVYMIS is co-administered with cyclosporine, the dosage of PREVYMIS should be decreased to 240 mg once daily (see sections 4.5 and 5.2).
Icelandic: Ef PREVYMIS er gefið samhliða cyclosporini á að minnka skammt PREVYMIS í 240 mg einu sinni á dag (sjá kafla 4.5 og 5.2).
English: If you are breast-feeding or are planning to breast-feed, tell your doctor before taking this medicine.
Icelandic: Ef þú ert með barn á brjósti eða ef brjóstagjöf er fyrirhuguð skaltu láta lækninn vita áður en þú byrjar að nota lyfið.
English: PREVYMIS concentrate for solution for infusion must be diluted prior to intravenous use.
Icelandic: PREVYMIS innrennslisþykkni, lausn verður að þynna fyrir notkun í bláæð.
English: Carcinogenesis Carcinogenicity studies with letermovir have not been conducted.
Icelandic: Krabbameinsvaldandi áhrif Ekki hafa verið gerðar rannsóknir á krabbameinsvaldandi áhrifum letermovirs.
English: Letermovir demonstrated superior efficacy over placebo in the analysis of the primary endpoint, as shown in Table 3.
Icelandic: Verkun letermovirs var betri en eftir lyfleysu í greiningu á aðalendapunkti eins og fram kemur í töflu
English: Letermovir may substantially increase plasma concentrations of these statins.
Icelandic: Letermovir getur aukið þéttni þessara statína í plasma verulega.
English: Concomitant administration with ergot alkaloids: (see sections 4.4 and 4.5).
Icelandic: Gjöf samhliða ergotalkalóíðum (sjá kafla 4.4 og 4.5).
English: (OATP1B1/3 inhibition)
Icelandic: (OATP1B1/3 hömlun)
English: Do not take PREVYMIS if any of the above apply to you.
Icelandic: Ekki skal nota PREVYMIS ef eitthvað af ofangreindu á við.
English: Frequent monitoring of sirolimus whole blood concentrations should be performed during treatment, when changing PREVYMIS administration route, and at discontinuation of PREVYMIS and the dose of sirolimus adjusted accordingly Frequent monitoring of sirolimus concentrations is recommended at initiation or discontinuation of cyclosporine coadministration with PREVYMIS.
Icelandic: Fylgjast á með þéttni sirolimus í heilblóði, með tíðum og reglubundnum hætti, meðan á meðferð stendur, þegar íkomuleið PREVYMIS er breytt og þegar meðferð með PREVYMIS er hætt og aðlaga skammt sirolimus í samræmi við það Mælt er með tíðu og reglulegu eftirliti með þéttni sirolimus þegar samhliða gjöf cyclosporins með PREVYMIS er hafin eða henni hætt.
English: Compatible intravenous solutions and other medicinal products
Icelandic: Samrýmanlegar lausnir í bláæð og önnur lyf
English: This medicine contains less than 1 mmol sodium (23 mg) per 240 mg tablet, that is to say essentially ‘sodium-free'.
Icelandic: Lyfið inniheldur minna en 1 mmól af natríum (23 mg) í hverri 240 mg töflu þ.e. sem næst natríumlaust.
English: Letermovir may increase the plasma concentrations of amiodarone.
Icelandic: Letermovir getur aukið plasmaþéttni amiodarons.
English: (OATP1B1/3 and/or P-gp inhibition)
Icelandic: (OATP1B1/3 og/eða P-gp hömlun)
English: • modafinil - for wakefulness
Icelandic: • modafinil - til að efla vökuvitund
English: • midazolam - used as a sedative
Icelandic: • midazolam - róandi lyf
English: When PREVYMIS is co-administered with cyclosporine, atorvastatin is contraindicated.
Icelandic: Þegar PREVYMIS er gefið samhliða cyclosporini á ekki að nota atorvastatin.
English: Marked increases in letermovir unbound exposure are anticipated in patients with moderate hepatic impairment combined with moderate or severe renal impairment (see section 4.2).
Icelandic: Gert er ráð fyrir áberandi aukningu á útsetningu fyrir óbundnu letermoviri hjá sjúklingum með meðalskerta lifrarstarfsemi sem eru einnig með meðalskerta eða alvarlega skerta nýrnastarfsemi (sjá kafla 4.2).
English: Administration instructions for PREVYMIS concentrate for solution for infusion
Icelandic: Leiðbeiningar um gjöf PREVYMIS innrennslisþykknis, lausnar
English: This medicine contains less than 1 mmol sodium (23 mg) per 480 mg tablet, that is to say essentially ‘sodium-free'.
Icelandic: Lyfið inniheldur minna en 1 mmól af natríum (23 mg) í hverri 480 mg töflu þ.e. sem næst natríumlaust.
English: PREVYMIS is not recommended in patients with moderate hepatic impairment combined with moderate or severe renal impairment (see section 5.2).
Icelandic: Notkun PREVYMIS er ekki ráðlögð hjá sjúklingum sem eru bæði með meðalskerta lifrarstarfsemi og meðalskerta eða alvarlega skerta nýrnastarfsemi (sjá kafla 5.2).
English: • Norepinephrine bitartrate
Icelandic: Noradrenalín bitartrat
English: Compatible intravenous bags and infusion set materials
Icelandic: Samrýmanleg efni í innrennslispokum og innrennslissettum
English: Efficacy and safety has not been demonstrated for patients with ESRD.
Icelandic: Ekki hefur verið sýnt fram á verkun og öryggi fyrir sjúklinga með nýrnasjúkdóm á lokastigi.
English: The mean apparent terminal half-life for letermovir is approximately 12 hours with 480 mg IV letermovir in healthy subjects.
Icelandic: Meðalgildi lokahelmingunartíma letermovirs er u.þ.b. 12 klst. eftir 480 mg af letermoviri í bláæð hjá heilbrigðum þátttakendum.
English: Each film-coated tablet contains 240 mg of letermovir.
Icelandic: Hver filmuhúðuð tafla inniheldur 240 mg letermovir.
English: Letermovir may decrease the plasma concentrations of dabigatran and may decrease efficacy of dabigatran.
Icelandic: Letermovir getur dregið úr plasmaþéttni dabigatrans og getur dregið úr verkun dabigatrans.
English: PREVYMIS is compatible with the following intravenous bags and infusion set materials.
Icelandic: PREVYMIS er samrýmanlegt eftirfarandi efnum í innrennslispokum og innrennslissettum.
English: Reasons for Failures
Icelandic: EÐA ÚRGANGS VEGNA
English: There were no differences in the incidence of or time to engraftment between the PREVYMIS and placebo groups.
Icelandic: Enginn munur var á tilvikum eða tíma fram að ígræðslu hjá þeim sem fengu PREVYMIS og þeim sem fengu lyfleysu.
English: midazolam (2 mg single dose PO) / letermovir (240 mg once daily PO)
Icelandic: midazolam (2 mg stakur skammtur til inntöku) / letermovir (240 mg einu sinni á dag til inntöku)
English: Each 12 mL vial contains 240 mg letermovir.
Icelandic: Hvert 12 ml hettuglas inniheldur 240 mg letermovir.
English: • changes in taste
Icelandic: • breytt bragðskyn
English: Each film-coated tablet contains 480 mg of letermovir.
Icelandic: Hver filmuhúðuð tafla inniheldur 480 mg letermovir.
English: (OATP1B1/3 and/or BCRP inhibition)
Icelandic: (OATP1B1/3 og/eða BCRP hömlun)
English: A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from PREVYMIS therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.
Icelandic: Vega þarf og meta kosti brjóstagjafar fyrir barnið og ávinning meðferðar fyrir konuna og ákveða á grundvelli matsins hvort hætta eigi brjóstagjöf eða hætta/stöðva tímabundið meðferð með PREVYMIS.
English: Each vial contains 240 mg or 480 mg letermovir.
Icelandic: Hvert hettuglas inniheldur 240 mg eða 480 mg letermovir.
English: Subjects were randomised (2:1) to receive either letermovir at a dose of 480 mg once daily adjusted to 240 mg when co-administered with cyclosporine, or placebo.
Icelandic: 480 mg einu sinni á dag aðlagað að 240 mg þegar það var gefið samhliða cyclosporini, eða lyfleysu.
English: Efficacy consistently favoured letermovir across subgroups including low and high risk for CMV reactivation, conditioning regimens, and concomitant immunosuppressive regimens (see Figure 2).
Icelandic: Hjá öllum undirhópunum var verkun letermovir í hag m.a. í undirhópum lítillar og mikillar hættu á endurvirkjun CMV, undirbúningsmeðferða og samhliða ónæmisbælandi meðferða (sjá mynd 2).
English: (intestinal P-gp induction)
Icelandic: (virkjun P-gp í þörmum)
English: tacrolimus (5 mg single dose)/ letermovir (480 mg daily)
Icelandic: tacrolimus (5 mg stakur skammtur)/ letermovir (480 mg daglega)
English: Close clinical monitoring for respiratory depression and/or prolonged sedation should be exercised during coadministration of PREVYMIS with midazolam.
Icelandic: öndunarbælingar og/eða langvarandi slævingar við samhliða gjöf PREVYMIS og midazolams.
English: posaconazole (300 mg single dose)/ letermovir (480 mg daily)
Icelandic: posaconazol (300 mg stakur skammtur)/ letermovir (480 mg daglega)
English: Figure 2: P001: Forest plot of the proportion of subjects initiating anti-CMV PET or with CMV end-organ disease through Week 24 post-transplant by selected subgroups (NC=F approach, FAS population)
Icelandic: Forest-graf sem sýnir hlutfall þeirra sem hófu and-CMV PET eða voru með sjúkdóm í marklíffæri af völdum CMV 24 vikum eftir ígræðslu samkvæmt völdum undirhópum (NC=F nálgun, greining á heildarþýði)
English: Letermovir may decrease the plasma concentrations of warfarin.
Icelandic: Letermovir getur dregið úr plasmaþéttni warfarins.
English: The recommended dosage of PREVYMIS is one 480 mg tablet once daily.
Icelandic: Ráðlagður skammtur af PREVYMIS er ein 480 mg tafla á dag.
English: PREVYMIS 480 mg tablets letermovir
Icelandic: PREVYMIS 480 mg töflur letermovir
English: Frequent monitoring of glucose concentrations is recommended the first 2 weeks after initiating or ending letermovir, as well as after changing route of administration of letermovir.
Icelandic: Ráðlagt er að fylgjast reglulega með þéttni glúkósa fyrstu 2 vikurnar eftir að gjöf letermovirs er hafin eða henni hætt, sem og eftir breytingu á íkomuleið letermovirs.
English: Figure 1: P001: Kaplan-Meier plot of time to initiation of anti-CMV PET or onset of CMV endorgan disease through Week 24 post-transplant in HSCT recipients (FAS population)
Icelandic: Kaplan-Meier graf yfir tímann þar til CMV hindrandi meðferð (PET) hefst eða CMV sjúkdómur kemur fram í marklíffæri 24 vikum eftir ígræðslu hjá þeim sem fengu blóðmyndandi stofnfrumuígræðslu (greining á heildarþýði)
English: Each 24 mL vial contains 480 mg of letermovir.
Icelandic: Hvert 24 ml hettuglas inniheldur 480 mg letermovir.
English: How to take • Swallow the tablet whole with some water.
Icelandic: Töflurnar á að gleypa heilar með nægu vatni.
English: Table 4: Letermovir AUC (ng•hr/mL) values in HSCT Recipients Treatment Regimen
Icelandic: Letermovir AUC (ng•klst./ml) gildi hjá þeim sem fengu blóðmyndandi stofnfrumuígræðslu
English: Medicinal products transported by P-gp in the intestine Letermovir is an inducer of intestinal P-gp.
Icelandic: Lyf sem eru flutt með P-gp í þörmum
English: 480 mg Oral, no cyclosporine
Icelandic: 480 mg til inntöku, án cyclosporins
English: Each 480 mg vial contains 46 mg sodium (main component of cooking/table salt).
Icelandic: Hvert 480 mg hettuglas inniheldur 46 mg af natríum (aðalefnið í matarsalti).
English: Endothelin antagonists bosentan
Icelandic: Endóþelínblokkar bosentan
English: Co-administration of PREVYMIS and bosentan is not recommended.
Icelandic: Gjöf PREVYMIS samhliða bosentani er ekki ráðlögð.
English: Letermovir is a moderate inducer of enzymes and transporters.
Icelandic: Letermovir er meðalöflugur virkir ensíma og ferja.
English: When PREVYMIS is co-administered with cyclosporine, refer also to the glyburide prescribing information for specific dosing recommendations.
Icelandic: Þegar PREVYMIS er gefið samhliða cyclosporini, sjá einnig sérstakar skammtaleiðbeiningar í samantekt á eiginleikum glyburids.
English: In HSCT recipients, bioavailability of letermovir was estimated to be approximately 35% with 480 mg once daily oral letermovir administered without cyclosporine.
Icelandic: 35% eftir inntöku 480 mg letermovirs einu sinni á dag gefið án cyclosporins.
English: Oral anticoagulants warfarin
Icelandic: Segavarnarlyf til inntöku warfarin
English: Antivirals acyclovir (400 mg single dose)/ letermovir (480 mg daily)
Icelandic: Veirulyf acyclovir (400 mg stakur skammtur)/ letermovir (480 mg daglega)
English: • Ceftaroline
Icelandic: Ceftarolin
English: Expected: ↑ CYP3A metabolised opioids
Icelandic: ↑ CYP3A umbrotnir ópíóíðar
English: Rifabutin may decrease plasma concentrations of letermovir.
Icelandic: Rifabutin getur dregið úr plasmaþéttni letermovirs.
English: PREVYMIS 240 mg concentrate for solution for infusion PREVYMIS 480 mg concentrate for solution for infusion letermovir
Icelandic: PREVYMIS 240 mg innrennslisþykkni, lausn PREVYMIS 480 mg innrennslisþykkni, lausn letermovir
English: Frequent monitoring for adverse reactions related to amiodarone is recommended during co-administration.
Icelandic: Mælt er með tíðu eftirliti m.t.t. aukaverkana af völdum amiodarons meðan á samhliða gjöf stendur.
English: Table 2: Adverse reactions identified with PREVYMIS Frequency
Icelandic: Aukaverkanir sem hafa komið fram með PREVYMIS Tíðni
English: PREVYMIS 240 mg tablets letermovir
Icelandic: PREVYMIS 240 mg töflur letermovir
English: Expected: ↑ quinidine
Icelandic: ↑ quinidin
English: PREVYMIS contains lactose monohydrate.
Icelandic: PREVYMIS inniheldur laktósaeinhýdrat.
English: Do not shake PREVYMIS vial.
Icelandic: Ekki hrista PREVYMIS hettuglas.
English: *Refer to the prescribing information to confirm compatibility of simultaneous co-administration.
Icelandic: *Sjá samantekt á eiginleikum lyfs til að staðfesta samrýmanleika á samhliðagjöf.
English: Each 240 mg vial contains 23 mg sodium (main component of cooking/table salt).
Icelandic: Hvert 240 mg hettuglas inniheldur 23 mg af natríum (aðalefnið í matarsalti).
English: 240 mg film-coated tablets
Icelandic: 240 mg filmuhúðaðar töflur
English: Adult CMV-seropositive recipients [R+] of an allogeneic hematopoietic stem cell transplant To evaluate letermovir prophylaxis as a preventive strategy for CMV infection or disease, the efficacy of letermovir was assessed in a multicenter, double-blind, placebo-controlled Phase 3 trial (P001) in adult CMV-seropositive recipients [R+] of an allogeneic HSCT.
Icelandic: Til að meta fyrirbyggjandi notkun letermovirs sem áætlun til að koma í veg fyrir CMV sýkingu eða sjúkdóm, var verkun letermovirs metin í fjölsetra, tvíblindri 3. stigs samanburðarrannsókn með lyfleysu (P001) hjá fullorðnum CMV-sermisjákvæðum [R+] einstaklingum sem hafa fengið ósamgena blóðmyndandi stofnfrumuígræðslu.
English: Thioridazine may decrease plasma concentrations of letermovir.
Icelandic: Thioridazin getur dregið úr plasmaþéttni letermovirs.
English: 480 mg film-coated tablets
Icelandic: 480 mg filmuhúðaðar töflur
English: PREVYMIS 240 mg concentrate for solution for infusion PREVYMIS 480 mg concentrate for solution for infusion
Icelandic: PREVYMIS 240 mg innrennslisþykkni, lausn PREVYMIS 480 mg innrennslisþykkni, lausn
English: The major elimination pathways of letermovir is biliary excretion as well as direct glucuronidation.
Icelandic: Aðalbrotthvarfsleið letermovirs er útskilnaður með galli sem og með glucurontengingu.
English: If PREVYMIS is co-administered with cyclosporine, the dosage of PREVYMIS should be decreased to 240 mg once daily (see sections 4.2 and 5.1).
Icelandic: Ef PREVYMIS er gefið samhliða cyclosporini skal minnka skammt PREVYMIS í 240 mg einu sinni á sólarhring (sjá kafla 4.2 og 5.1).
English: • you take the following herbal product:
Icelandic: ef þú notar eftirtalið jurtalyf:
English: At baseline, 31% of subjects were at high risk for reactivation as defined by one or more of the following criteria: Human Leukocyte Antigen (HLA)-related (sibling) donor with at least one mismatch at one of the following three HLA-gene loci: HLA-A, -B or -DR, haploidentical donor; unrelated donor with at least one mismatch at one of the following four HLA-gene loci: HLA-A, -B,C and -DRB1; use of umbilical cord blood as stem cell source; use of ex vivo T-cell-depleted grafts; Grade 2 or greater Graft-Versus-Host Disease (GVHD), requiring systemic corticosteroids.
Icelandic: HLA-A, -B, -C og -DRB1; notkun stofnfrumna úr naflastrengsblóði; notkun ígræðis sem T-frumur hafa verið fjarlægðar úr ex vivo; minnst 2. stigs hýsilsótt sem krefst notkunar altækra barkstera.
English: Do not stop taking PREVYMIS
Icelandic: Ekki má nota PREVYMIS
English: In HSCT recipients, co-administration of cyclosporine increased plasma concentrations of letermovir due to inhibition of OATP1B.
Icelandic: Hjá þeim sem fengu blóðmyndandi stofnfrumuígræðslu jók samhliða gjöf cyclosporins plasmaþéttni letermovirs vegna OATP1B hömlunar.
English: Based on population pharmacokinetic analyses, letermovir AUC is estimated to be 33.2% higher in Asians compared to Whites.
Icelandic: 33,2% hærra hjá Asíumönnum miðað við hjá hvítum einstaklingum.
English: sirolimus (2 mg single dose)/ letermovir (480 mg daily)
Icelandic: sirolimus (2 mg stakur skammtur)/ letermovir (480 mg daglega)
English: Phenytoin may decrease plasma concentrations of letermovir.
Icelandic: Phenytoin getur dregið úr plasmaþéttni letermovirs.
English: PREVYMIS 480 mg film-coated tablets
Icelandic: PREVYMIS 480 mg filmuhúðaðar töflur
English: PREVYMIS 240 mg film-coated tablets
Icelandic: PREVYMIS 240 mg filmuhúðaðar töflur
English: Weeks Post-Transplant
Icelandic: Vikur eftir ígræðslu
English: • significant decrease of concomitant medicinal product plasma concentrations which may lead to reduced therapeutic effect of the concomitant medicinal product.
Icelandic: verulega minnkaðri plasmaþéttni samhliða lyfja, sem getur dregið úr verkun þeirra lyfja.
English: Antifungals fluconazole (400 mg single dose)/letermovir (480 mg single dose)
Icelandic: Sveppalyf fluconazol (400 mg stakur skammtur)/ letermovir (480 mg stakur skammtur)
English: • Cefazolin sodium
Icelandic: Cefazolin natríum
English: Incompatible intravenous bags and infusion set materials PREVYMIS concentrate for solution for infusion is incompatible with polyurethane-containing IV administration set tubing.
Icelandic: Ósamrýmanleg efni í innrennslispokum og innrennslissettum PREVYMIS innrennslisþykkni, lausn er ósamrýmanlegt slöngum í innrennslissettum sem innihalda polyurethan.
English: Pharmacotherapeutic group: Antivirals for systemic use, direct acting antivirals, ATC code: J05AX18
Icelandic: Veirulyf til altækrar notkunar (systemic use), með beina verkun á veirur, ATC-flokkur:
English: (600 mg single dose IV)/ letermovir (480 mg single dose PO)
Icelandic: (600 mg stakur skammtur i.v./ letermovir (480 mg stakur skammtur til inntöku)
English: Bosentan may decrease plasma concentrations of letermovir.
Icelandic: Bosentan getur dregið úr plasmaþéttni letermovirs.
English: Letermovir also appears to be subject to P-gp and BCRP mediated efflux in the liver and intestine (see section 5.2).
Icelandic: P-gp og BCRP (sjá kafla 5.2).
English: (600 mg once daily PO)/ letermovir (480 mg once daily PO)
Icelandic: (600 mg einu sinni á dag til inntöku/ letermovir (480 mg einu sinni á dag til inntöku)
English: If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.
Icelandic: Við meðgöngu, grun um þungun eða ef þungun er fyrirhuguð skal leita ráða hjá lækninum áður en lyfið er notað.
English: Nevirapine may decrease plasma concentrations of letermovir.
Icelandic: Nevirapin getur dregið úr plasmaþéttni letermovirs.
English: Combined hepatic and renal impairment
Icelandic: LYFJAFORM OG INNIHALD
English: After dilution, PREVYMIS should be administered by intravenous infusion via peripheral or central venous catheter using a total time of approximately 60 minutes.
Icelandic: Eftir þynningu skal heildartíminn við gjöf PREVYMIS með innrennsli í bláæð með út- eða miðlægum bláæðarlegg vera u.þ.b. 60 mínútur.
English: Outer carton for 240 mg concentrate for solution for infusion
Icelandic: Ytri askja fyrir 240 mg innrennslisþykkni, lausn
English: Herbal products St. John's wort (Hypericum perforatum)
Icelandic: Jurtalyf Jóhannesarjurt (Hypericum perforatum)
English: Peripheral blood (n=241, 117)
Icelandic: Útæðablóð (n=241, 117) Beinmergur (n=72, 43)
English: • Ampicillin sodium
Icelandic: Ampicillin natríum
English: (600 mg single dose PO)/ letermovir (480 mg single dose PO)
Icelandic: (600 mg stakur skammtur til inntöku/ letermovir (480 mg stakur skammtur til inntöku)
English: Efavirenz may decrease plasma concentrations of letermovir.
Icelandic: Efavirenz getur dregið úr plasmaþéttni letermovirs.
English: (induction of CYP2C19)
Icelandic: (CYP2C19 virkjun)
English: Concomitant use is not recommended.
Icelandic: Samhliðanotkun er ekki ráðlögð.
English: Catheters Radiopaque polyurethane
Icelandic: Holleggir Geislaþétt polyurethan.
English: Nafcillin may decrease plasma concentrations of letermovir.
Icelandic: Nafcillin getur dregið úr plasmaþéttni letermovirs.
English: Sedatives midazolam (1 mg single dose IV)/ letermovir (240 mg once daily PO)
Icelandic: Róandi lyf midazolam (1 mg stakur skammtur í bláæð)/ letermovir (240 mg einu sinni á dag til inntöku)
English: PREVYMIS 480 mg film-coated tablets letermovir
Icelandic: PREVYMIS 480 mg filmuhúðaðar töflur letermovir
English: • If cyclosporine is initiated after starting PREVYMIS, the next dose of PREVYMIS should be decreased to 240 mg once daily.
Icelandic: Ef gjöf cyclosporins er hafin eftir að byrjað er að nota PREVYMIS á að minnka næsta skammt af
English: Based on population pharmacokinetic analyses, the mean steady-state volume of distribution is estimated to be 45.5 L following intravenous administration in HSCT recipients.
Icelandic: Samkvæmt þýðisgreiningu á lyfjahvörfum var mat á meðaldreifingarrúmmáli við jafnvægi 45,5 l eftir gjöf í bláæð hjá þeim sem fengu blóðmyndandi stofnfrumuígræðslu.
English: Missed dose
Icelandic: Ósamrýmanleg lyf
English: Outer carton for 480 mg film-coated tablets
Icelandic: Ytri askja fyrir 480 mg filmuhúðaðar töflur
English: Antidiabetic medicinal products repaglinide
Icelandic: LYFJAGERÐARFRÆÐILEGAR UPPLÝSINGAR
English: Favors Letermovir
Icelandic: ↔ letermovir
English: No dose adjustment required.
Icelandic: Ekki þarf að aðlaga skammta.
English: Letermovir may increase statin plasma concentrations.
Icelandic: Letermovir getur aukið þéttni statína í plasma.
English: - Examples of medicinal products metabolised by UGT1A1 are raltegravir and dolutegravir.
Icelandic: UGT1A1 eru raltegravir og dolutegravir.
English: Co-administration of PREVYMIS and etravirine is not recommended.
Icelandic: Gjöf PREVYMIS samhliða etravirini er ekki ráðlögð.
English: • loss of appetite
Icelandic: • mikil þreytutilfinning