FrancophonIA/ELRC3.0 huggingface dataset:
English: • Injection site reactions (such as bruising, pain, irritation, itching and rash)
Croatian: • Reakcije na mjestu injiciranja (kao što su modrice, bol, nadraženost, svrbež i osip) • Porast enzima gušterače (kao što su lipaza i amilaza).
English: If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
Croatian: U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka, obratite se liječniku, ljekarniku ili medicinskoj sestri.
English: A stepwise approach to insulin dose reduction is recommended.
Croatian: Preporučuje se smanjenje doze inzulina korak po korak.
English: Few cases of acute pancreatitis (<0.2%) have been reported during long-term, controlled phase 3 clinical trials with Victoza.
Croatian: Tijekom dugotrajnih kontroliranih kliničkih ispitivanja lijeka Victoza faze 3 prijavljeno je nekoliko slučajeva akutnog pankreatitisa (<0,2%).
English: Gastrointestina l disorders
Croatian: Gastrointestinalne nuspojave
English: Five double-blind, randomised, controlled clinical phase 3a adult trials were conducted to evaluate the effects of liraglutide on glycaemic control (Table 2).
Croatian: Djelovanje liraglutida na regulaciju glikemije procjenjivalo se u pet dvostruko slijepih, randomiziranih, kontroliranih kliničkih ispitivanja faze 3a u odraslih osoba (Tablica 2).
English: In an open label trial comparing the efficacy and safety of liraglutide (1.2 mg and 1.8 mg) and sitagliptin (a DPP-4 inhibitor, 100 mg) in patients inadequately controlled on metformin therapy (mean HbA1c 8.5%), liraglutide at both doses was statistically superior to sitagliptin treatment in reducing HbA1c after 26 weeks (-1.24%, -1.50% vs -0.90%, p<0.0001).
Croatian: U otvorenom ispitivanju u kojem je uspoređivana djelotvornost i sigurnost liraglutida (1,2 mg i 1,8 mg) i sitagliptina (DPP-4 inhibitor, 100 mg) u bolesnika koji nisu odgovarajuće kontrolirani liječenjem metforminom (srednja vrijednost HbA1c 8,5%), liraglutid je u obje doze bio statistički superiorniji u odnosu na liječenje sitagliptinom u smanjenju HbA1c nakon 26 tjedana (-1,24%, -1,50% naspram -0,90%, p<0,0001).
English: In a 104-week clinical trial, 57% of patients with type 2 diabetes treated with insulin degludec in combination with metformin achieved a target HbA1c <7% and the remaining patients continued in a
Croatian: U kliničkom ispitivanju koje je trajalo 104 tjedna, 57% bolesnika sa šećernom bolešću tipa 2 liječenih degludek inzulinom u kombinaciji s metforminom postiglo je ciljni HbA1c <7%, a preostali bolesnici nastavili su sudjelovati u 26-tjednom, otvorenom ispitivanju te su randomizirani tako da je liječenju dodan liraglutid ili jedna doza aspart inzulina (uz najveći obrok).
English: (CrCL 30-59 ml/min, see section 5.1) had 26% lower liraglutide exposure when compared with a separate trial including patients with type 2 diabetes with normal renal function or mild renal impairment.
Croatian: Slično tome, u 26-tjednom kliničkom ispitivanju, bolesnici sa šećernom bolešću tipa 2 i umjerenim oštećenjem bubrega (CrCl 30-59 ml/min, vidjeti dio 5.1) imali su 26% nižu izloženost liraglutidu u usporedbi sa zasebnim ispitivanjem koje je uključivalo bolesnike sa šećernom bolešću tipa 2 s normalnom bubrežnom funkcijom ili blažim oštećenjem bubrega.
English: For use by one person only
Croatian: Lijek smije primjenjivati samo jedna osoba.
English: - if you are allergic to liraglutide or any of the other ingredients of this medicine (listed in section
Croatian: Što morate znati prije nego počnete primjenjivati lijek Victoza Nemojte primjenjivati lijek Victoza - ako ste alergični na liraglutid ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
English: Serious side effects
Croatian: Ozbiljne nuspojave
English: Mean weight change from baseline (kg)
Croatian: Srednja vrijednost promjene tjelesne težine od početne vrijednosti (kg)
English: Your pen comes with 18 mg of liraglutide.
Croatian: Vaša brizgalica sadrži 18 mg liraglutida.
English: The pen is designed to be used with NovoFine or NovoTwist disposable injection needles up to a length of 8 mm and as thin as 32G (0.25/0.23 mm).
Croatian: 8 mm i ne tanjim od 32G (0,25/0,23 mm).
English: To improve gastro-intestinal tolerability, the starting dose is 0.6 mg liraglutide daily.
Croatian: Početna doza je 0,6 mg liraglutida na dan, kako bi se poboljšala gastrointestinalna podnošljivost lijeka.
English: EXP Discard pen 1 month after first use.
Croatian: Mjesec dana nakon prve primjene brizgalicu baciti u otpad.
English: Non-cardiovascular death
Croatian: Smrt uzrokovana kardiovaskularnim događajem
English: 2 inhibitor (SGLT2i)) and/or insulin.
Croatian: pioglitazon, sulfonilureja, inhibitor suprijenosnika natrija-glukoze 2 (inhibitor SGLT2)) i/ili inzulin.
English: • Headache
Croatian: • Glavobolja
English: • Toothache
Croatian: • Zubobolja
English: • Fasting plasma glucose
Croatian: • Glukoza u plazmi natašte
English: Liraglutide in combination with metformin, glimepiride, metformin and rosiglitazone or SGLT2i ± metformin resulted in a statistically significant greater proportion of patients achieving an HbA1c ≤6.5% at 26 weeks compared with patients receiving these agents alone.
Croatian: SGLT2 ± metforminom doveo je do statistički značajno većeg udjela bolesnika koji su postigli HbA1c ≤6,5% nakon 26 tjedana u usporedbi s bolesnicima koji su primali ove lijekove samostalno.
English: Name and address of the manufacturer responsible for batch release
Croatian: Naziv i adresa proizvođača odgovornog za puštanje serije lijeka u promet Novo Nordisk A/S
English: • Immunogenicity
Croatian: • Imunogenost
English: Vomiting Dyspepsia Abdominal pain upper
Croatian: Bolovi u gornjem dijelu abdomena Konstipacija
English: Common: may affect up to 1 in 10 people
Croatian: Često: mogu se javiti u do 1 na 10 osoba
English: Urticaria Pruritus
Croatian: Mučnina Proljev
English: Cholelithiasis and cholecystitis
Croatian: Kolelitijaza Kolecistitis
English: A mean increase in heart rate from baseline of 2 to 3 beats per minute has been observed with liraglutide in long-term clinical trials including LEADER.
Croatian: U dugotrajnim kliničkim ispitivanjima, uključujući ispitivanje LEADER, primijećena je srednja vrijednost porasta srčane frekvencije za 2-3 otkucaja u minuti u odnosu na početnu vrijednost.
English: ss
Croatian: D.
English: Gender had no clinically meaningful effect on the pharmacokinetics of liraglutide based on the results of population pharmacokinetic data analysis of male and female patients and a pharmacokinetic study in healthy subjects.
Croatian: Prema rezultatima analize populacijskih farmakokinetičkih podataka bolesnika i bolesnica te farmakokinetičkog ispitivanja u zdravih ispitanika, spol nije imao klinički značajnog učinka na farmakokinetiku liraglutida.
English: Ethnic origin had no clinically relevant effect on the pharmacokinetics of liraglutide based on the results of population pharmacokinetic analysis which included patients of White, Black, Asian and Hispanic groups.
Croatian: Prema rezultatima populacijske farmakokinetičke analize koja je obuhvatila bolesnike bijele, crne, azijske i hispano skupine, etničko podrijetlo nije imalo klinički značajnog utjecaja na farmakokinetiku liraglutida.
English: Add-on to SGLT2i5 ± metformin (≥1500 mg/day)
Croatian: Dodatak inhibitoru SGLT25 ± metforminu (≥1500 mg/dan) Liraglutid 1,8 mg
English: At week 26, the estimated mean change in HbA1c was -1.4% and -0.5% for liraglutide and placebo, respectively, with an estimated treatment difference of -0.9 [-1.00; -0.70]95% CI.
Croatian: uz liraglutid i -0,5% uz placebo, uz procijenjenu razliku između liječenja od -0,9 [-1,00; -0,70]95% CI.
English: One pre-filled pen contains 18 mg liraglutide.
Croatian: Jedna napunjena brizgalica sadrži 18 mg liraglutida.
English: Add-on to metformin (2,000 mg/day) + rosiglitazone (4 mg twice daily) Liraglutide 1.2 mg 177 8.48
Croatian: Dodatak metforminu (2000 mg/dan) + roziglitazonu (4 mg dvaput na dan)
English: • Indigestion
Croatian: • Umor
English: No severe hypoglycaemic episodes occurred in the liraglutide treatment group.
Croatian: U grupi liječenoj liraglutidom nisu zabilježene epizode teške hipoglikemije.
English: A single dose administration of digoxin 1 mg with liraglutide resulted in a reduction of digoxin AUC by 16%; Cmax decreased by 31%.
Croatian: Digoksin Primjena jedne doze digoksina od 1 mg s liraglutidom rezultirala je smanjenjem AUC digoksina za
English: Liraglutide
Croatian: Omaglica
English: - The active substance is liraglutide.
Croatian: Što Victoza sadrži - Djelatna tvar je liraglutid.
English: Hypoglycaemia
Croatian: Hipoglikemija
English: Victoza 6 mg/ml solution for injection in pre-filled pen Liraglutide
Croatian: Victoza 6 mg/ml otopina za injekciju u napunjenoj brizgalici liraglutid
English: The reductions in HbA1c and superiority vs sitagliptin observed after 26 weeks of liraglutide treatment (1.2 mg and 1.8 mg) were sustained after 52 weeks of treatment (-1.29% and -1.51% vs -0.88%, p<0.0001).
Croatian: Smanjenje HbA1c i superiornost naspram sitagliptina opažena nakon 26 tjedana liječenja liraglutidom (1,2 mg i 1,8 mg)
English: Read the package leaflet before use.
Croatian: NAČIN I PUT PRIMJENE LIJEKA Prije uporabe pročitajte uputu o lijeku.
English: The incidence of withdrawal due to adverse reactions was 7.8% for liraglutide-treated patients and 3.4% for comparator-treated patients in the long-term controlled trials (26 weeks or longer).
Croatian: U dugotrajnim kontroliranim ispitivanjima (26 tjedana ili duže) incidencija prestanka primjene lijeka zbog nuspojava bila je 7,8% u bolesnika liječenih liraglutidom i 3,4% u bolesnika liječenih lijekom usporedbe.
English: EXP
Croatian: Osip
English: Summary of the safety profile
Croatian: 4.8 Nuspojave Sažetak sigurnosnog profila
English: • Inflamed gallbladder
Croatian: • Upala žučnog mjehura
English: Few cases of anaphylactic reactions with additional symptoms such as hypotension, palpitations, dyspnoea and oedema have been reported with marketed use of Victoza.
Croatian: Nakon stavljanja lijeka Victoza na tržište, prijavljeno je nekoliko slučajeva anafilaktičkih reakcija s dodatnim simptomima kao što su hipotenzija, palpitacije, dispneja i edem.
English: Acute pancreatitis has been observed with the use of GLP-1 receptor agonists.
Croatian: Kod primjene agonista receptora GLP-1 primijećen je akutni pankreatitis.
English: Digoxin median tmax was delayed from 1 h to 1.5 h. No adjustment of digoxin dose is required based on these results.
Croatian: Medijan tmax digoksina bio je odgođen sa 1 h na 1,5 h.
English: Monotherapy
Croatian: Monoterapija
English: Fatigue Injection site reactions
Croatian: Opći poremećaji i reakcije na mjestu primjene
English: Victoza 6 mg/ml solution for injection in pre-filled pen
Croatian: Victoza 6 mg/ml otopina za injekciju u napunjenoj brizgalici
English: Placebo Victoza
Croatian: UPUTE ZA UPORABU BRIZGALICE VICTOZA
English: Uncommon: may affect up to 1 in 100 people
Croatian: Manje često: mogu se javiti u do 1 na 100 osoba
English: PC:
Croatian: C.
English: In an open label trial comparing the efficacy and safety of liraglutide 1.8 mg once daily and exenatide 10 mcg twice daily in patients inadequately controlled on metformin and/or sulfonylurea therapy (mean HbA1c 8.3%), liraglutide was statistically superior to exenatide treatment in reducing HbA1c after 26 weeks (-1.12% vs -0.79%; estimated treatment difference: -0.33; 95% CI: -0.47 to -0.18).
Croatian: U otvorenom ispitivanju u kojem je uspoređivana djelotvornost i sigurnost liraglutida 1,8 mg jednom dnevno i eksenatida 10 µg dvaput dnevno u bolesnika koji nisu odgovarajuće kontrolirani liječenjem metforminom i/ili sulfonilurejom (srednja vrijednost HbA1c 8,3%), liraglutid je bio statistički superiorniji u odnosu na liječenje eksenatidom u smanjenju HbA1c nakon 26 tjedana (-1,12%
English: Favours Victoza Favours Placebo
Croatian: U korist placeba
English: Liraglutide did not change the overall exposure of paracetamol following a single dose of 1000 mg. Paracetamol Cmax was decreased by 31% and median tmax was delayed up to 15 min. No dose adjustment for concomitant use of paracetamol is required.
Croatian: Cmax paracetamola smanjio se za 31%, dok je medijan tmax bio odgođen do 15 min.
English: Liraglutide 1.8 mg 203 8.00
Croatian: Liraglutid 1,8 mg
English: • Dizziness
Croatian: Dispepsija
English: Liraglutide should not be used in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.
Croatian: Preosjetljivost na djelatnu tvar ili neku od pomoćnih tvari navedenih u dijelu 6.1. 4.4 Posebna upozorenja i mjere opreza pri uporabi Liraglutid se ne smije primjenjivati u bolesnika sa šećernom bolešću tipa 1 niti za liječenje dijabetičke ketoacidoze.
English: Investigations
Croatian: Pretrage
English: The dose selector clicks when you turn it. Do not use these clicks to select your dose.
Croatian: Nemojte koristiti taj zvuk za odabir doze.
English: Liraglutide did not change the overall exposure of griseofulvin following administration of a single dose of griseofulvin 500 mg. Griseofulvin Cmax increased by 37% while median tmax did not change.
Croatian: Liraglutid nije promijenio ukupnu izloženost grizeofulvinu nakon primjene jedne doze grizeofulvina od 500 mg.
English: NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER
Croatian: 11. NAZIV I ADRESA NOSITELJA ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET Novo Nordisk A/S
English: When you have found the most convenient time of the day it is preferred that you inject Victoza around the same time of the day.
Croatian: Vam je najprikladnije, poželjno je lijek Victoza injicirati otprilike u isto vrijeme svakog dana.
English: The contraceptive effect is therefore anticipated to be unaffected when co-administered with liraglutide.
Croatian: Stoga se smatra kako istodobna primjena liraglutida ne utječe na kontraceptivni učinak tih lijekova.
English: In five large long-term clinical phase 3a trials over 2,500 adult patients have received treatment with Victoza alone or in combination with metformin, a sulfonylurea (with or without metformin) or metformin plus rosiglitazone.
Croatian: U pet velikih dugotrajnih kliničkih ispitivanja faze 3a više od 2500 odraslih bolesnika primalo je lijek
English: How to use Victoza
Croatian: U korist lijeka Victoza
English: Add-on to metformin (2,000 mg/day) + glimepiride (4 mg/day) Liraglutide 1.8 mg 230 8.3
Croatian: Dodatak metforminu (2000 mg/dan) + glimepiridu (4 mg/dan)
English: Liraglutide 1.2 mg 251 8.18
Croatian: Liraglutid 1,2 mg Liraglutid 1,8 mg Placebo
English: - If you get any side effects, talk to your doctor, pharmacist or nurse.
Croatian: - Ako primijetite bilo koju nuspojavu, potrebno je obavijestiti liječnika, ljekarnika ili medicinsku sestru.
English: Liraglutide lowered ethinyloestradiol and levonorgestrel Cmax by 12 and 13%, respectively, following administration of a single dose of an oral contraceptive product.
Croatian: Nakon primjene jedne doze oralnog kontraceptiva, liraglutid je smanjio Cmax etinilestradiola za 12%, a levonorgestrela za 13%.
English: No dose adjustment of lisinopril is required based on these results.
Croatian: Na osnovi ovih rezultata, nije potrebno prilagođavanje doze lizinoprila.
English: • Bowel obstruction.
Croatian: • Opstrukcija crijeva.
English: In an open label trial comparing the efficacy and safety of liraglutide 1.8 mg with lixisenatide 20 mcg in 404 patients inadequately controlled on metformin therapy (mean HbA1c 8.4%), liraglutide was superior to lixisenatide in reducing HbA1c after 26 weeks of treatment (-1.83% vs -1.21%, p<0.0001).
Croatian: U otvorenom ispitivanju u kojem je uspoređivana djelotvornost i sigurnost liraglutida 1,8 mg i liksisenatida 20 µg u 404 bolesnika koji nisu odgovarajuće kontrolirani liječenjem metforminom (srednja vrijednost HbA1c 8,4%), liraglutid je bio superioran liksisenatidu u smanjenju HbA1c nakon
English: Biotransformation
Croatian: Koronarna revaskularizacija
English: Headache Dizziness
Croatian: Poremećaji srca
English: Subcutaneous use
Croatian: Za supkutanu primjenu
English: • Malaise (feeling unwell)
Croatian: • Opće loše stanje (malaksalost)
English: ≤5.5 mmol/l (≤100 mg/dl) Target
Croatian: Samoodređivanje glukoze u plazmi natašte Povećanje doze glargin inzulina (IU) ≤5,5 mmol/l (≤100 mg/dl) ciljno
English: Tabulated list of adverse reactions
Croatian: Tablični prikaz nuspojava
English: Marketing Authorisation Holder and Manufacturer
Croatian: Nositelj odobrenja za stavljanje lijeka u promet i proizvođač Novo Nordisk A/S
English: Very few episodes (0.001 events/patient year) were observed with administration of liraglutide in combination with oral antidiabetics other than sulfonylureas.
Croatian: zabilježeno je kad se liraglutid primjenjivao u kombinaciji s drugim oralnim antidijabeticima osim sulfonilureje.
English: 1 ml of solution contains 6 mg of liraglutide*.
Croatian: KVALITATIVNI I KVANTITATIVNI SASTAV Jedan ml otopine sadrži 6 mg liraglutida*.
English: No episodes of severe hypoglycaemia were observed in the trial with liraglutide used as monotherapy.
Croatian: U ispitivanju liraglutida u monoterapiji nisu zapažene epizode teške hipoglikemije.
English: • Tiredness
Croatian: • Omaglica
English: Withdrawal
Croatian: Povraćanje
English: In a double-blind trial comparing the efficacy and safety of liraglutide 1.8 mg versus placebo as addon to insulin and/or OAD in patients with type 2 diabetes and moderate renal impairment, liraglutide was superior to placebo treatment in reducing HbA1c after 26 weeks (-1.05% vs -0.38%).
Croatian: U dvostruko slijepom ispitivanju koje je usporedilo djelotvornost i sigurnost 1,8 mg liraglutida u usporedbi s placebom kao dodatka terapiji inzulinom i/ili OAD u bolesnika sa šećernom bolešću tipa 2
English: Liraglutide 1.2 mg 228 8.5
Croatian: Liraglutid 1,2 mg
English: Liraglutide 1.8 mg 234 8.5
Croatian: Roziglitazon 4 mg/dan 231 8,4
English: Digoxin
Croatian: Gastritis
English: 140 (2 x 70) tablets (multipack)
Croatian: 140 (2 x 70) tableta (višestruko pakiranje)
English: Strength
Croatian: Sastav
English: MA (EU) number (Invented) name
Croatian: Broj (EU) odobrenja
English: Pharmaceutical Form
Croatian: Zaštićeno ime Doza Farmaceutski oblik Put primjene Unutarnje pakiranje
English: • At the request of the European Medicines Agency;
Croatian: • Na zahtjev Europske agencije za lijekove;
English: Keep the bottle tightly closed.
Croatian: Bočicu čuvati čvrsto zatvorenu.
English: This may take up to 2 years.
Croatian: Za to može biti potrebno i do dvije godine.
English: Interactions studies have only been performed in adults.
Croatian: Ispitivanja interakcija provedena su samo u odraslih.
English: The mechanism of this effect is unclear.
Croatian: Nije jasan mehanizam tog učinka.
English: Check with your doctor or pharmacist if you are not sure.
Croatian: Provjerite sa svojim liječnikom ili ljekarnikom ako niste sigurni.
English: After this, most patients need a dose of:
Croatian: Nakon toga većini bolesnika treba sljedeća doza:
English: There is no preferential uptake in erythrocytes.
Croatian: Nema preferencijalnog preuzimanja u eritrocitima.
English: Aluminium / Aluminium blister.
Croatian: Aluminij/aluminij blister.
English: DATE OF FIRST AUTHORISATION / RENEWAL OF THE AUTHORISATION
Croatian: DATUM PRVOG ODOBRENJA/DATUM OBNOVE ODOBRENJA
English: The duration may be modified depending on clinical or laboratory variables.
Croatian: Trajanje postupka može se promijeniti ovisno o kliničkim ili laboratorijskim varijablama.
English: Do not take a double dose to make up for a forgotten dose.
Croatian: Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
English: • Additional risk minimisation measures
Croatian: • Dodatne mjere minimizacije rizika
English: Fertility was not reduced.
Croatian: Fertilnost nije bila smanjena.
English: Procreation (recommendations for men)
Croatian: Planiranje obitelji (preporuke za muškarce)
English: Always take this medicine exactly as your doctor or pharmacist has told you.
Croatian: Uvijek uzmite ovaj lijek točno onako kako Vam je rekao Vaš liječnik ili ljekarnik.
English: CYP450 inhibitors and inducers
Croatian: CYP450 inhibitori i induktori
English: If possible, take your tablets or the box with you to show the doctor.
Croatian: Ako je moguće, ponesite tablete ili kutiju sa sobom i pokažite je liječniku.
English: The elimination half-life in patients is approximately 2 weeks.
Croatian: Poluvijek eliminacije u bolesnika iznosi približno 2 tjedna.
English: For more information on these, please read section 4 (Possible side effects).
Croatian: Za daljnje informacije o tome molimo pročitajte dio 4 (Moguće nuspojave).
English: Use of alternative contraceptive methods is recommended.
Croatian: Preporučuje se primjena alternativnih metoda kontracepcije.
English: Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
Croatian: Pažljivo pročitajte cijelu uputu prije nego počnete uzimati ovaj lijek jer sadrži Vama važne podatke.
English: For washout procedures and other recommended actions in case of desired or unintended pregnancy, see section 4.6.
Croatian: Za postupak ispiranja i ostale preporučene aktivnosti u slučaju željene ili neplanirane trudnoće vidjeti dio 4.6.
English: This leaflet was last revised in {MM/YYYY} Other sources of information
Croatian: Ova uputa je zadnji puta revidirana u {MM/GGGG} Drugi izvori informacija
English: An updated RMP should be submitted:
Croatian: Nadopunjeni RMP treba dostaviti:
English: Most of the cases occurred within the first 6 months of treatment.
Croatian: Većina slučajeva pojavila se tijekom prvih 6 mjeseci liječenja.
English: This includes medicines obtained without a prescription.
Croatian: To uključuje lijekove koje ste nabavili bez recepta.
English: Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Croatian: Obavijestite svog liječnika ili ljekarnika ako uzimate, nedavno ste uzeli ili biste mogli uzeti bilo koje druge lijekove.
English: In rats and dogs, Heinz bodies and/or Howell-Jolly bodies were found.
Croatian: U štakora i pasa nađena su Heinzova tjelešca i/ili Howell-Jolly tjelešca.
English: Infections may be more severe in nature and may, therefore, require early and vigorous treatment.
Croatian: Infekcije mogu biti teže prirode i stoga može biti potrebno rano i intenzivno liječenje.
English: Duration of a complete washout is usually 11 days.
Croatian: Potpuno ispiranje postiže se obično za 11 dana.
English: • every two weeks during the first six months of treatment, and
Croatian: • svaka dva tjedna tijekom prvih šest mjeseci liječenja, te
English: U kabelovny 130 102 37 Prague 10 Czech Republic
Croatian: U kabelovny 130 102 37 Prague 10 Češka Republika
English: If you are affected, do not drive, or use machines.
Croatian: Ako se to dogodi, nemojte voziti ni upravljati strojevima.
English: In such cases patients should refrain from driving cars and using machines.
Croatian: U tim slučajevima bolesnici trebaju izbjegavati upravljanje vozilima i strojevima.
English: Before starting treatment, all patients should be evaluated for active and inactive (“latent”) tuberculosis, as per local recommendations.
Croatian: Prije početka liječenja za sve bolesnike potrebno je utvrditi imaju li aktivnu ili neaktivnu („latentnu“) tuberkulozu, prema lokalnim preporukama.
English: Your doctor may perform additional tests for differential diagnosis.
Croatian: Vaš liječnik treba provesti dodatna testiranja za postavljanje diferencijalne dijagnoze.
English: UNIQUE IDENTIFIER - HUMAN READABLE DATA PC:
Croatian: JEDINSTVENI IDENTIFIKATOR - PODACI ČITLJIVI LJUDSKIM OKOM PC:
English: - if you have ever had tuberculosis or if you have been in close contact with someone who has or has had tuberculosis.
Croatian: - ako ste ikad imali upalu pluća (intersticijsku plućnu bolest) - ako ste ikad imali tuberkulozu ili ako ste bili u bliskom kontaktu s nekim tko ima ili je imao tuberkulozu.
English: Warfarin and other coumarine anticoagulants
Croatian: Varfarin i drugi kumarinski antikoagulansi
English: Peripheral neuropathy
Croatian: Periferna neuropatija