FrancophonIA/DGT-Translation_Memory huggingface dataset:
English: Washington, DC: National Academies Press.
Portuguese: Washington, DC. National Academies Press.
Finnish: painos. Washington, DC: National Academies Press.
English: , Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances, Toxicologist, 96, 235.
French: , Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances, Toxicologist, 96 (S-1), 235.
Portuguese: Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances. Toxicologist, 96, 235.
Finnish: Toxicologist 96, s. 235.
Slovak: L., DiDonato, L. and DeGeorge, G. L. (2007), Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances, Toxicologist, 96, 235.
English: , Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice, Drug.
Portuguese: Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice. Drug.
Finnish: Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice. Drug. Chem.
English: Chem.
Finnish: Toxicol.
Slovak: Drug.
Lithuanian: Drug.
English: , An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions, Toxicol.
Portuguese: An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions.
Finnish: An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions. Toxicol. Appl.
English: Appl.
Portuguese: Toxicol. Appl.
Finnish: Pharmacol.
English: , A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals, Toxicol.
Portuguese: A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals. Toxicol.
Finnish: A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals. Toxicol. Meth.
English: , Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods, Drug.
Portuguese: Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods. Drug.
Finnish: Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods. Drug. Chem.
English: , A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round.
Portuguese: A European interlaboratory validation of alternative endpoints of the murine local lymph node assay: first round.
Finnish: A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round. Toxicol.
English: , The local lymph node assay being too sensitive?
Portuguese: The local lymph node assay being too sensitive?
Finnish: The local lymph node assay being too sensitive? Arch.
English: Arch.
Finnish: Toxicol.
English: EpiSkinTM (SM)
Finnish: EpiSkinTM (ihomalli)
English: EpiDermTM SIT (EPI-200)
Finnish: EpiDermTM-ihoärsytystesti (EPI-200)
English: SkinEthicTM RHE
Finnish: SkinEthicTM-RhE-menetelmä
English: , In vitro skin irritation: fact and future.
Italian: ,In vitro skin irritation: fact and future.
Portuguese: In vitro skin irritation: fact and future. State of the art review of mechanisms and models.
Finnish: State of the art review of mechanisms and models.
English: , Determination of skin irritation potential in the human 4-h patch test.
Portuguese: Determination of skin irritation potential in the human 4-h patch test.
Finnish: Determination of skin irritation potential in the human 4-h patch test.
English: physical nature and purity; physico-chemical properties relevant to the conduct of the study;
Finnish: tutkimuksen tekemisen kannalta merkitykselliset fysikaaliskemialliset ominaisuudet
English: Mol.
Portuguese: Environ. Mol.
Finnish: Mol. Mutagen.
Slovak: P., Holland, N., Kirsch-Volders, M., Zeiger, E., Ban, S., Barale, R., Bigatti, M. P., Bolognesi, C., Jia, C., Di Giorgio, M., Ferguson, L. R., Fucic, A., Lima, O. G., Hrelia, P., Krishnaja, A. P., Lee, T. K., Migliore, L., Mikhalevich, L., Mirkova, E., Mosesso, P., Muller, W. U., Odagiri, Y., Scarffi, M. R., Szabova, E., Vorobtsova, I., Vral, A. and Zijno, A. (2001), HUman MicroNucleus Project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes, I. Effect of laboratory protocol, scoring criteria and host factors on the frequency of micronuclei, Environ.
English: , Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody, Environ.
Portuguese: Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody.
Finnish: Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ.
English: , International Commission for Protection Against Environmental Mutagens and Carcinogens, Genotoxicity under extreme culture conditions.
Portuguese: International Commission for Protection Against Environmental Mutagens and Carcinogens, Genotoxicity under extreme culture conditions.
Finnish: International Commission for Protection Against Environmental Mutagens and Carcinogens, Genotoxicity under extreme culture conditions.
English: Pathol.
Portuguese: J. Environ. Pathol.
Finnish: J. Environ. Pathol. Toxicol.
English: , Alternatives to Aroclor 1254-induced S9 in in-vitro genotoxicity assays.
Portuguese: Alternatives to Aroclor 1254-induced S9 in in-vitro genotoxicity assays.
Finnish: Alternatives to Aroclor 1254-induced S9 in in-vitro genotoxicity assays.
English: , Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or Aroclor 1254 induced rat S-9, Environ.
French: , Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or Aroclor 1254 induced rat S-9. Environ.
Portuguese: Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or Aroclor 1254 induced rat S-9.
Finnish: Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or Aroclor 1254 induced rat S-9. Environ.
English: , CHO/HGPRT Mutation Assay: Evaluation of Gases and Volatile Liquids, In: Tice, R.R., Costa, D.L. and Schaich, K.M. (eds), Genotoxic Effects of Airborne Agents.
Finnish: CHO/HGPRT Mutation Assay: Evaluation of Gases and Volatile Liquids, teoksessa: Tice, R. R., Costa, D. L. ja Schaich, K. M. (ed.), Genotoxic Effects of Airborne Agents.
English: , Evaluation of an exposure system using cells grown on collagen gels for detecting highly volatile mutagens in the CHO/HGPRT mutation assay, Environ.
Portuguese: Evaluation of an exposure system using cells grown on collagen gels for detecting highly volatile mutagens in the CHO/HGPRT mutation assay. Environ.
Finnish: Evaluation of an exposure system using cells grown on collagen gels for detecting highly volatile mutagens in the CHO/HGPRT mutation assay. Environ.
English: , A protocol for the in vitro micronucleus test.
Portuguese: A protocol for the in vitro micronucleus test.
Finnish: A protocol for the in vitro micronucleus test.
Slovak: P. (2002), A protocol for the in vitro micronucleus test.
English: Molec.
Portuguese: Environ. Molec.
Finnish: Environ. Molec.
English: A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent NC group treated only with the vehicle for the test substance, and a PC (concurrent or recent, based on laboratory policy in considering paragraphs 11-15). Testing multiple doses of the PC should be considered, especially when testing the PC on an intermittent basis.
Finnish: Kussakin annostasoryhmässä on oltava vähintään neljä eläintä, ja testiaineesta on käytettävä vähintään kolmea konsentraatiota; lisäksi käytetään samanaikaisesti määritettävää negatiivista kontrolliryhmää, joka käsitellään vain testiaineen kantaja-aineella, sekä positiivista kontrolliryhmää (joka määritetään samanaikaisesti tai joka on määritetty hiljattain, laboratorion toimintatavan mukaisesti, ottaen huomioon 11–15 kohdat).
English: , The local lymph node assay: status of validation.
Portuguese: The local lymph node assay: status of validation.
Finnish: The local lymph node assay: status of validation. Food Chem.
Maltese: The local lymph node assay: status of validation.
English: , The local lymph node assay: A viable alternative to currently accepted skin sensitisation tests.
Portuguese: The local lymph node assay: A viable alternative to currently accepted skin sensitisation tests.
Finnish: The local lymph node assay: A viable alternative to currently accepted skin sensitisation tests. Food Chem.
English: Food Chem.
Finnish: Food Chem. Toxicol.
English: Pharmacol.
Portuguese: Toxicol.
Finnish: Toxicol.
English: Toxicol.
Finnish: Meth.
English: J. Immunol.
Finnish: J. Immunol. Meth.
English: , Development of a bioluminescent ATP assay to quantify mammalian and bacterial cell number from a mixed population.
Portuguese: Development of a bioluminescent ATP assay to quantify mammalian and bacterial cell number from a mixed population.
Finnish: Development of a bioluminescent ATP assay to quantify mammalian and bacterial cell number from a mixed population. Biomat.
English: Meth.
Finnish: Enzymol.
English: 7th ed.
French: édition.
Portuguese: Institute of Laboratory Animal Research (ILAR) Guide for the Care and Use of Laboratory Animals, 7.a edição.
Finnish: painos.
Maltese: 7 edizzjoni.
English: , The murine local lymph node assay: regulatory and potency considerations under REACH.
Portuguese: The murine local lymph node assay: regulatory and potency considerations under REACH.
Finnish: The murine local lymph node assay: regulatory and potency considerations under REACH. Toxicol.
English: , The local lymph node assay: developments and applications.
Portuguese: The local lymph node assay: developments and applications.
Finnish: The local lymph node assay: developments and applications. Toxicol.
English: , Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances.
Portuguese: Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances.
Finnish: Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances.
Slovak: L., DiDonato, L., and DeGeorge, G. L. (2007), Use of an enhanced local lymph node assay to correctly classify irritants and false positive substances.
English: Toxicologist, 96, 235.
Finnish: Toxicologist 96, s. 235.
English: , Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice.
Portuguese: Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice.
Finnish: Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice. Drug Chem.
English: Drug.
Finnish: Chem.
English: , An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions.
Portuguese: An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions.
Finnish: An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions.
English: , A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals.
Portuguese: A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals.
Finnish: A combined murine local lymph node and irritancy assay to predict sensitisation and irritancy potential of chemicals. Toxicol.
English: , Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods.
Italian: , Contact sensitivity to selected acrylate compounds in B6Cice: relative potency, cross reactivity, and comparison of test methods.
Portuguese: Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods.
Finnish: Contact sensitivity to selected acrylate compounds in B6C3F1 mice: relative potency, cross reactivity, and comparison of test methods. Drug.
English: Drug Chem.
Finnish: Toxicol.
English: Environ.
Portuguese: J. Toxicol. Environ.
Finnish: Health Perspect.
English: , Assessment of the skin sensitisation potential of topical medicaments using the local lymph node assay: An interlaboratory exercise.
Portuguese: Assessment of the skin sensitisation potential of topical medicaments using the local lymph node assay: An interlaboratory exercise.
Finnish: Assessment of the skin sensitisation potential of topical medicaments using the local lymph node assay: An interlaboratory exercise.
Maltese: An interlaboratory exercise.
English: For example, if a false negative result is obtained in the periodic PC study, negative test substance results obtained in the interval between the last acceptable periodic PC study and the unacceptable periodic PC study may be questioned. Implications of these outcomes should be carefully considered when determining whether to include concurrent PCs or to only conduct periodic PCs.
Finnish: Jos esimerkiksi saadaan väärä negatiivinen tulos, kun positiivinen kontrolli ei ole ollut aina samanaikaisesti mukana, positiivisen kontrollikemikaalin viimeisen hyväksytyn yksittäisen tutkimuksen ja positiivisen kontrollikemikaalin hylätyn yksittäisen tutkimuksen tuloksen välisenä aikana saadut testiaineen negatiiviset tulokset voivat olla kyseenalaisia.
English: J. Appl.
Finnish: Toxicol.
English: NIH Publication Number 09-7357.
Swedish: NIH Publication Number 09–7357.
Finnish: NIH-julkaisunumero 09-7357.
Lithuanian: NIH Publication Number 09–7357.
English: , A European inter- laboratory validation of alternative endpoints of the murine local lymph node assay: first round.
Portuguese: A European inter- laboratory validation of alternative endpoints of the murine local lymph node assay: first round.
Finnish: A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round. Toxicol.
Maltese: , A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round.
English: Although the PC should be tested in the vehicle that is known to elicit a consistent response (e.g. acetone: olive oil; 4:1, v/v), there may be certain regulatory situations in which testing in a non-standard vehicle (clinically/chemically relevant formulation) will also be necessary (24). If the concurrent PC is tested in a different vehicle than the test substance, then a separate VC for the concurrent PC should be included.
French: Quoique le témoin positif doive être testé dans un véhicule déclenchant un effet constant (par exemple acétone/huile d’olive (4:1, v/v)], certaines situations réglementaires nécessitent aussi l’essai d’un véhicule moins courant (mélange cliniquement ou chimiquement pertinent) (24). Si le TP concurrent est testé avec un véhicule différent de celui de la substance d’essai, il convient de mettre en place un essai témoin indépendant pour le véhicule du TP.
English: Inject 250 μL of sterile phosphate-buffered saline (PBS) containing 20 μCi (7,4 × 105 Bq) of tritiated (3H)-methyl thymidine into all test and control mice via the tail vein. Alternatively, inject 250 μL sterile PBS containing 2 μCi (7,4 × 104 Bq) of 125I-iododeoxyuridine and 10–5M fluorodeoxyuridine into all mice via the tail vein.
French: Il est également possible d’injecter 250 μL de PBS stérile contenant 2 μCi (7,4 × 104 Bq) de 125I-iododésoxyuridine et de la fluorodésoxyuridine à 10-5 M dans la veine caudale de toutes les souris.
English: OECD (2002), Skin Sensitisation: Local Lymph Node Assay. OECD Guideline for the Testing of Chemicals No 429, Paris.
French: OCDE (2002), Sensibilisation cutanée: essai des ganglions lymphatiques locaux, Ligne directrice no 429, Lignes directrices de l’OCDE pour les essais de produits chimiques, OCDE, Paris.
English: OECD (1992), Skin Sensitisation. OECD Guideline for Testing of Chemicals No 406, OECD, Paris.
French: OCDE (1992), Sensibilisation de la peau, Ligne directrice no 406, Lignes directrices de l’OCDE pour les essais de produits chimiques, OCDE, Paris.
English: ICCVAM (2009), The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) Test Method Evaluation Report. The Reduced Murine Local Lymph Node Assay: An Alternative Test Method Using Fewer Animals to Assess the Allergic Contact Dermatitis Potential of Chemicals and Products, NIH Publication Number 09-6439, Research Triangle Park, NC: National Institute of Environmental Health Sciences.
French: ICCVAM (2009), The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) Test Method Evaluation Report, The Reduced Murine Local Lymph Node Assay: An Alternative Test Method Using Fewer Animals to Assess the Allergic Contact Dermatitis Potential of Chemicals and Products, NIH Publication Number 09-6439, Research Triangle Park, NC: National Institute of Environmental Health Sciences.
English: OECD (2002), Acute Dermal Irritation/Corrosion. OECD Guideline for Testing of Chemicals No 404, Paris, France.
French: OCDE (2002), Effet irritant/corrosif aigu sur la peau, Ligne directrice no 404, Lignes directrices de l’OCDE pour les essais de produits chimiques, OCDE, Paris.
English: , A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round. Toxicol., 212, 60-68.
French: , A European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round, Toxicol., 212, 60-68.
English: AOO
French: AHO
Portuguese: AAZ
English: MEK
French: MEC
English: A benchmark substance should have the following properties: (i) consistent and reliable source(s); (ii) structural and functional similarity to the class of substances being tested; (iii) known physicochemical characteristics; (iv) supporting data on known effects; and (v) known potency in the range of the desired response. Estimated concentration threshold (ECt) Estimated concentration of a test substance needed to produce a stimulation index that is indicative of a positive response. Estimated concentration three (EC3) Estimated concentration of a test substance needed to produce a stimulation index of three. False negative A test substance incorrectly identified as negative or non-active by a test method, when in fact it is positive or active. False positive A test substance incorrectly identified as positive or active by a test, when in fact it is negative or non-active. Hazard The potential for an adverse health or ecological effect. The adverse effect is manifested only if there is an exposure of sufficient level.
French: Une substance étalon doit posséder les propriétés suivantes: i) provenir d’une ou de plusieurs sources régulières et fiables; ii) présenter une similitude structurale et fonctionnelle avec la classe des substances testées; iii) posséder des caractéristiques physico-chimiques connues; iv) être accompagnée de données confirmant ses effets connus; et v) avoir une puissance connue dans l’intervalle de la réponse désirée.
English: Inter-laboratory reproducibility A measure of the extent to which different qualified laboratories, using the same protocol and testing the same test substances, can produce qualitatively and quantitatively similar results. Inter-laboratory reproducibility is determined during the pre-validation and validation processes, and indicates the extent to which a test can be successfully transferred between laboratories, also referred to as between-laboratory reproducibility (14). Intra-laboratory reproducibility A determination of the extent that qualified people within the same laboratory can successfully replicate results using a specific protocol at different times. Also referred to as within-laboratory reproducibility (14). Me-too test A colloquial expression for a test method that is structurally and functionally similar to a validated and accepted reference test method. Such a test method would be a candidate for catch-up validation. Interchangeably used with similar test method (14).
French: Valeur aberrante une valeur aberrante est une valeur observée qui diffère nettement des autres valeurs dans un échantillon aléatoire d’une population.
English: 2 Liquid No Cat. (Optional Cat. 3) [3], [4] cyclamen aldehyde
French: cuményl-2-méthylpropionaldéhyde
English: UN (2009), United Nations Globally Harmonised System of Classification and Labelling of Chemicals (GHS), Third revised edition, UN New York and Geneva. Available at: [http://www.unece.org/trans/danger/publi/ghs/ghs_rev03/03files_e.html]
French: Nations unies (2009), Système général harmonisé de classification et d’étiquetage des produits chimiques (SGH), Troisième édition révisée, ONU New York et Genève, 2007, disponible à l’adresse suivante: [http://www.unece.org/trans/danger/publi/ghs/ghs_rev03/03files_f.html].
English: OECD (2004), Acute Dermal Irritation/Corrosion, OECD Guideline for the Testing of Chemicals No 404, OECD, Paris. Available at: [http://www.oecd.org/env/testguidelines]
French: OCDE (2002), Effet irritant/corrosif aigu sur la peau, Ligne directrice no 404, Lignes directrices pour les essais de produits chimiques, OCDE, Paris, disponible à l’adresse suivante: [http://www.oecd.org/env/testguidelines]
English: OECD (2004), In Vitro Skin Corrosion: Transcutaneous Electrical Resistance (TER), OECD Guideline for the Testing of Chemicals No 430, OECD, Paris. Available at: [http://www.oecd.org/env/testguidelines]
French: OCDE (2004), Corrosion cutanée in vitro: Essai de résistance électrique transcutanée (TER), Ligne directrice no 430, Lignes directrices pour les essais de produits chimiques, OCDE, Paris, disponible à l’adresse suivante: [http://www.oecd.org/env/testguidelines]
English: OECD (2004), In Vitro Skin Corrosion: Human Skin Model Test, OECD Guideline for the Testing of Chemicals No 431, OECD, Paris. Available at: [http://www.oecd.org/env/testguidelines]
French: OCDE (2004), Corrosion cutanée in vitro: Essai sur modèle de peau humaine, Ligne directrice no 431, Lignes directrices pour les essais de produits chimiques, OCDE, Paris, disponible à l’adresse suivante: [http://www.oecd.org/env/testguidelines]
English: OECD (2006), In Vitro Membrane Barrier Test Method for Skin Corrosion, OECD Guideline for the Testing of Chemicals No 435, OECD, Paris. Available at: [http://www.oecd.org/env/testguidelines]
French: OCDE (2006), Méthode d’essai in vitro sur membrane d’étanchéité pour la corrosion cutanée, Lignes directrices no 435, Ligne directrice pour les essais de produits chimiques, OCDE, Paris, disponible à l’adresse suivante: [http://www.oecd.org/env/testguidelines]
English: EC-ECVAM (2009), Performance Standards for in vitro skin irritation test methods based on Reconstructed human Epidermis (RhE)? Available at: [http://ecvam.jrc.ec.europa.eu]
French: EC-ECVAM (2009), Performance Standards for in vitro skin irritation test methods based on Reconstructed human Epidermis (RhE), disponible à l’adresse suivante: [http://ecvam.jrc.ec.europa.eu]
English: Hoffmann, S. (2006), ECVAM skin irritation validation study phase II: Analysis of the primary endpoint MTT and the secondary endpoint IL1-α. Available at: [http://ecvam.jrc.ec.europa.eu]
French: Hoffmann, S. (2006), ECVAM skin irritation validation study phase II: Analysis of the primary endpoint MTT and the secondary endpoint IL1-α, disponible à l’adresse suivante: [http://ecvam.jrc.ec.europa.eu]