FrancophonIA/DGT-Translation_Memory huggingface dataset:
English: Stephan, C.E. Methods for calculating an LC50. In Aquatic Toxicology and Hazard Evaluation (edited by F.I. Mayer and J.L. Hamelink).
Slovak: Stephan, C. E. Method for calculating an LC50 Toxicology and Hazard Evaluation (edited by F. I. Mayer and J. L. Hamelink).
English: A computer program for calculating an LC50. US EPA.
Slovak: A computer program for calculating an LC50 US EPA.
English: DATA Data should be summarised in tabular form, showing for each treatment group and control, the number of daphnids used, immobilisation at each observation. The percentages immobilised at 24 hours and 48 hours are plotted against test concentrations.
Slovak: ÚDAJE
English: An OECD inter-laboratory comparison exercise, done in 1988, has shown that the methods give consistent results. However, depending on the physical characteristics of the substance to be tested, one or other of the methods may be preferred. I.2. SELECTION OF THE APPROPRIATE METHOD
Slovak: Medzilaboratórny porovnávací test OECD, vykonaný v roku 1988, ukázal, že metódy poskytujú zhodné výsledky.
English: In order to select the most appropriate method, information on the chemical's solubility, vapour pressure and adsorption characteristics is essential. The chemical structure or formula should be known in order to calculate theoretical values and/or check measured values of parameters, e.g. ThOD, ThCO2, DOC, TOC, COD (see Appendices 1 and 2). Test chemicals which are soluble in water to at least 100 mg/l may be assessed by all methods, provided they are non-volatile and non-adsorbing. For those chemicals which are poorly soluble in water, volatile or adsorbing, suitable methods are indicated in Table 1.
Slovak: V závislosti od fyzikálneho charakteru látky, ktorá má byť testovaná, sa však môže dávať prednosť určitej metóde.
English: The manner in which poorly water-soluble chemicals and volatile chemicals can be dealt with is described in Appendix 3. Moderately volatile chemicals may be tested by the DOC Die-Away method if there is sufficient gas space in the test vessels (which should be suitably stoppered). In this case, an abiotic control must be set up to allow for any physical loss. Table 1: Applicability of test methods Test Analytical Method Suitability for substances which are: poorly soluble volatile adsorbing DOC Die-Away Dissolved organic carbon – – +/– Mod. OECD Die-Away Dissolved organic carbon – – +/– CO2 Evolution Respirometry: CO2 evolution + – + Manometric Respirometry Manometric respirometry: oxygen consumption + +/– + Closed Bottle Respirometry: dissolved oxygen +/– + + MITI Respirometry: oxygen consumption + +/– +
Slovak: VÝBER VHODNEJ SKÚŠOBNEJ METÓDY
English: A further source for the inoculum is surface water. In this case, collect a sample of an appropriate surface water, e.g. river, lake, and keep aerobic until required.
Slovak: V tomto prípade sa odoberie vzorka z vhodnej povrchovej vody, napr. rieky, jazera a udržiava sa v aeróbnom stave.
English: Cs(o)
Slovak: Ca(i)
English: If the percentage degradation of aniline calculated from the oxygen consumption does not exceed 40 % after seven days and 65 % after 14 days, the test is regarded as invalid. VII.3.3. Reporting
Slovak: Ak percento degradácie anilínu, vypočítané zo spotreby kyslíka, nepresahuje 40 % po 7 dňoch a 65 % po 14 dňoch, test sa považuje za neplatný.
English: DATA SHEET An example of a data sheet is given below. MITI (I) TEST 1. LABORATORY 2. DATE AT START OF TEST 3. TEST SUBSTANCE Name: Stock solution concentration: mg/1 as chemical Initial concentration in medium, Co: … mg/1 as chemical
Slovak: Pozri I.8.
English: ThOD: … mg O2/1 4. INOCULUM
Slovak: Príklad karty údajov je uvedený nižšie.
English: … (6) …
Slovak: LABORATÓRIUM
English: … (7) …
Slovak: DÁTUM ZAČIATKU TESTU
English: 13,15 ml. HCl + 25 ml. KCl dil. to 100 ml 1,6 8,3 ml. HCl + 25 ml. KCl dil. to 100 ml
Slovak: 13,15 ml HCl + 25 ml KCl zriediť na 100 ml
English: 2,63 ml. 0,1 N HCl + 50 ml. biphthalate to 100 ml 3,8 0,1 M potassium biphthalate +0,1 N NaOH at 20 oC 0,40 ml. 0,1 N NaOH + 50 ml. biphthalate to 100 ml 4,0
Slovak: 2,63 ml 0,1 N HCl + 50 ml hydrogénftalánu do 100 ml
English: 0,1 N NaOH + 50 ml. biphthalate to 100 ml 4,6
Slovak: 12,15 ml 0,1 N NaOH + 50 ml hydrogénftalánu do 100 ml
English: 45,20 ml. 0,1 N NaOH + 50 ml. phosphate to 100 ml 7,8 46,80 ml. 0,1 N NaOH + 50 ml. phosphate to 100 ml
Slovak: 45,20 ml 0,1 N NaOH + 50 ml dihydrogénfosforečnanu do 100 ml
English: 0,1 M H3B03 in 0,1 M KCl +0,1 N NaOH at 20 oC 2,61 ml.
Slovak: 46,80 ml 0,1 N NaOH + 50 ml 100 ml dihydrogénfosforečnanu do 100 ml
English: KOLTHOFF AND VLEESCHHOUWER: Citrate buffers of KOLTHOFF and VLEESCHHOUWER [2] Composition pH
Slovak: 43,90 ml 0,1 N NaOH + 50 ml kyseliny trihydrogénboritej do 100 ml
English: 0,1 N HCl + 50 ml. citrate to 100 ml 2,2 43,4 ml. 0,1 N HCl + 50 ml. citrate to 100 ml 2,4 36,8 ml. 0,1 N HCl + 50 ml. citrate to 100 ml
Slovak: 0,1 M citran draselný a 0,1 N HCl pri 18 oC [2]49,7 ml 0,1 N HCl + 50 ml citranu do 100 ml
English: 0,1 N HCl + 50 ml. citrate to 100 ml 3,0
Slovak: 30,2 ml 0,1 N HCl + 50 ml citranu do 100 ml
English: 0,1 N HCl + 50 ml. citrate to 100 ml 3,2 10,7 ml.
Slovak: 23,6 ml 0,1 N HCl + 50 ml citranu do 100 ml
English: 0,1 N NaOH + 50 ml. citrate to 100 ml 4,4
Slovak: 16,3 ml 0,1 N NaOH + 50 ml citranu do 100 ml
English: 0,1 N NaOH + 50 ml. citrate to 100 ml 4,6 39,2 ml. 0,1 N NaOH + 50 ml. citrate to 100 ml
Slovak: 23,7 ml 0,1 N NaOH + 50 ml citranu do 100 ml
English: Test procedure Test concentrations
Slovak: Postup testu
English: Range finding test The range of concentrations just causing mortalities of 0 to 100 % may be determined in a range-finding test to provide information on the range of concentrations to be used in the definitive test.
Slovak: Koncentrácie testovanej látky sú vyjadrené ako hmotnosť látky na hmotnosť sušiny základného substrátu (mg/kg).
English: The substance should be tested at the following concentrations: 1000; 100; 10; 1; 0,1 mg substance/kilogram test substrate (dry weight). If a full definitive test is to be carried out, one test batch per concentration and one for the untreated control, each with 10 worms, could be sufficient for the range-finding test. Definitive test
Slovak: Test na vyhľadávanie rozsahu
English: The results of the range-finding test are used to choose at least five concentrations in a geometric series just spanning the range 0 to 100 % mortality and differing by a constant factor not exceeding 1,8. Tests using these series of concentration should allow the LC50 value and its confidence limits to be estimated as precisely as possible. In the definitive test at least four test batches per concentration and four untreated controls, each with 10 worms, are used. The results of these replicate batches are given as a mean and standard deviation.
Slovak: Rozpätie koncentrácií spôsobujúcich mortalitu od 0 do 100 % môže byť stanovené v teste na vyhľadávanie rozsahu, pri ktorom sa získajú informácie o tom, ktoré koncentrácie sa použijú v konečnom teste.
English: When two consecutive concentrations, at a ratio of 1,8, give only 0 % and 100 % mortality, these two values are sufficient to indicate the range within which the LC50 falls. Mixture of the basic test substrate and the test substance The test substrate should, whenever possible, be made up without any additional agents other than water. Immediately before the start of the test, an emulsion or dispersion of the test substance in deionised water or other solvent is mixed with the basic test substrate, or sprayed evenly over it with a fine chromatographic or similar spray. If insoluble in water, the test substance can be dissolved in as small a volume as possible of suitable organic solvent (e.g. hexane, acetone or chloroform). Only agents which volatilise readily may be used to solubilise, disperse or emulsify the test substance. The test substrate must be ventilated before use. The amount of water evaporated must be replaced. The control should contain the same quantity of any additive agent. If the test substance is not soluble, dispersible or emulsifiable in organic solvents, 10 g of a mixture of fine ground quartz sand and a quantity of test substance necessary to treat 500 g dry weight of artificial soil are mixed with 490 g of dry weight of test substrate.
Slovak: Látka by mala byť testovaná v nasledovných koncentráciách: 1000; 100; 10; 1; 0,1 mg látky/kilogram testovacieho substrátu (sušiny).
English: Degradation %
Slovak: degradáde
English: Analysis Specific
Slovak: Chemická spotreba kyslíka
English: COD DOC
Slovak: Rozpustený organický uhlík
English: If this is not possible because of the 1 % of LC50 criterion and the analytical limit, a lower factor than ten can be used or the use of 14C labelled test substance should be considered. No concentration used should be above the solubility of the test substance.
Slovak: Ak to z dôvodu kritéria 1 % hodnoty LC50 alebo analytického prahu nie je možné, potom možno použiť faktor nižší ako 10 alebo treba uvažovať o označení testovanej látky izotopom14 C. Nesmú sa používať koncentrácie, ktoré sú vyššie ako rozpustnosť testovanej látky.
English: Shiner perch Cymatogaster aggregata
Slovak: Cymatogaster aggregata
English: Gasterosteus aculeatus Sea bass
Slovak: Dicentracus labrax
English: Dicentracus labrax Bleak
Slovak: belička európska
English: Spacie A. and Hamelink J.L. (1982) Alternative models for describing the bioconcentration of organics in fish. Environ. Toxicol. and Chem.
Slovak: Spacie A. a Hamelink J. L. (1982), Alternative models for describing the bloconcentration of organics in fish.
English: Danish Water Quality Institute.
Swedish: Danska vattenkvalitetsinstitutet.
Slovak: Water Quality Institute, Denmark.
English: Chiou C.T. and Schmedding D.W. (1982) Partitioning of organic compounds in octanol-water systems.
Slovak: Chiou C T, a Schmedding D. W, (1982), Partitioning of organic Compounds in octanol-water systems.
English: Environ. Sci. Technol.
Slovak: Environ, Sci.
English: Hawker D.W. and Connell D.W. (1988) Influence of partition coefficient of lipophilic compounds on bioconcentration kinetics with fish.
Slovak: Hawker D. W. and Connell D, W, (1988). influence of partition coefficient of lipophilic compounds on bioconcentration kinetics with fish. Wat.
English: Branson D.R., Blau G.E., Alexander H.C. and Neely W.B. (1975) Transactions of the American Fisheries Society, 104 (4), pp 785-792.
Slovak: Branson D. R., Blau G. E,, Alexander H. C and Neely W, B. (1975), Transactions of the American Fisheries Society, 104 (4), pp, 785 – 792.
English: Guidelines for the optimal design of experiments to estimate parameters in first order kinetic models, Can. J. Chem. Eng.
Slovak: Guidelines for the optimal design of experiments to estimate parameters in first order kinetic models, Can, J. Chem. Eng.
English: Rainbow trout (Oncorhynchus mykiss) is the recommended species for this test since most experience has been gained from ring-test with this species (1)(2). However, other well documented species can be used but the test procedure may have to be adapted to provide suitable test conditions.
Slovak: Pstruh dúhový (Oncorhynchus mykiss) je odporúčaným druhom na tento test odvtedy, čo sa v skupinových testoch získalo dostatočné množstvo skúseností s týmto druhom (1), (2).
English: A ring-test (2) has shown that, for rainbow trout, a loading rate of 16 trouts of 3-5 g in a 40-litre volume is acceptable. Recommended frequency of water removal during the test is 6 litres/g of fish/day.
Slovak: Skupinové testy (2) ukázali, že u pstruha dúhového je prípustné nasadenie množstva 16 pstruhov o hmotnosti 3 – 5 g v objeme 40 l. Odporúčaná frekvencia výmeny vody počas testu je 6 l/g na telesnú hmotnosť ryby/deň.
English: Logarithmic series of concentrations suitable for toxicity test (9) Column (Number of concentrations between 100 and 10, or between 10 and 1) [1] 1 2 3 4 5 6 7 100
Slovak: Logaritmické série koncentrácií vhodných na test na toxicitu (9)
English: The test is begun by placing fertilised eggs in the test chambers and is terminated just before the yolk-sac of any larvae in any of the test chambers has been completely absorbed or before mortalities by starvation start in controls. Lethal and sub-lethal effects are assessed and compared with control values to determine the lowest observed effect concentration and hence the no observed effect concentration.
Slovak: Test začína umiestnením oplodnených vajíčok do testovacej komory a končí práve predtým, ako ktorákoľvek z lariev v ktorejkoľvek testovanej komore komplexne absorbuje žĺtkový vak alebo pred uhynutím v dôsledku začínajúceho hladovania v kontrolnej komore.
English: Where egg containers, grids or meshes have been used to hold eggs within the main test vessel, these restraints should be removed after the larvae hatch [13] OECD, Paris, 1992, Test Guideline 210, ‘Fish, Early-life Stage Toxicity Test’. , except that meshes should be retained to prevent the escape of the fish.
Slovak: Ak sa v hlavnej testovacej nádobe na zadržiavanie vajíčok použili kontajnery, mriežky alebo sieťky, potom po vyliahnutí lariev môžu byť tieto zábrany odstránené [2] s výnimkou, ak mriežky preventívne zabraňujú úniku rýb.
English: The use of fewer than five concentrations, for example in limit tests, and a narrower concentration interval may be appropriate in some circumstances. Justification should be provided if fewer than five concentrations are used.
Slovak: Za určitých okolností je vhodné použiť menej ako päť koncentrácií, napr. v limitných testoch a v užších koncentračných intervaloch.
English: Environ. Tox.
Slovak: Environ.
English: Amer. Statist.
Slovak: Amer. Statist.
English: Adult worker honeybees (Apis mellifera) are exposed to a range of doses of the test substance dispersed in sucrose solution. The bees are then fed the same diet, free of the test substance.
Slovak: Dospelé robotnice včiel obecných (Apis mellifera) sú vystavené celému radu dávok testovanej látky, ktorá je rozptýlená v roztoku sacharózy.
English: Dose: is the amount of test substance applied. Dose is expressed as mass (μg) of test substance per test animal (μg/bee).
Slovak: Dávka: je množstvo skonzumovanej testovanej látky a je vyjadrená ako hmotnosť (μg) testovanej látky na testovaného živočícha (μg/včelu).
English: Abbott, W.S., (1925) A method for computing the effectiveness of an insecticide. Jour.
Slovak: Abbott, W.S.(1925). A method for computing the effectiveness of an insecticide.
English: The use of non-labelled test substances with known composition and preferably at least 95 % purity or of radiolabelled test substances with known composition and radio-purity, is recommended. In the case of short half-life tracers, decay corrections should be applied.
Slovak: Odporúča sa použitie neoznačkovaných testovacích látok so známym zložením aspoň 95 % čistoty alebo u rádiooznačených látok o známom zložení a rádio-čistoty v prípade krátkej polovičnej doby rozpadu by sa mali aplikovať korekcie na rozpad.
English: The analytical methods which can be used for sorption measurements include gas-liquid chromatography (GLC), high-performance liquid chromatography (HPLC), spectrometry (e.g. GC/mass spectrometry, HPLC/mass spectrometry) and liquid scintillation counting (for radiolabelled substances). Independent of the analytical method used, it is considered suitable if the recoveries are between 90 % and 110 % of the nominal value.
Slovak: Medzi analytické metódy, ktoré môžme použiť na sorpčné merania, patria chromatografia plyn – kvapalina (GLC), vysoko účinná kvapalinová chromaografia (HPLC), spektrometria (GC/hmotnostná spektrometria – plynová chromatografia v kombinácii s hmotnostnou spektrometriou), HPLC/hmotnostná spektrometria – kvapalinová chromatografia v kombinácii s hmotnostnou spektrometriou) a kvapalné scintilačné počítadlo (na látky označené rádioaktívnou látkou).
English: The applicable relationship is obtained by rearranging equation (4) of the Kd in the form of equation (1): V0 msoil =m0 ms ads eq -1 Kd
Slovak: V tomto zámere je predpoklad, že adsorpčná rovnováha je v lineárnom vzťahu.
English: %/100 (2) Fig. 1 Relationship between soil to solution ratios and Kd at various percentages of adsorbed test substance Soil to Solution Ratio Distribution coefficient Kd (cm3 g–1)
Slovak: alebo v logaritmickej forme, ktorá predpokladá, že: R = mpôda/V0 a Aeq %/100 =ms
English: Fig. 1 shows soil/solution ratios required as a function of Kd for different levels of adsorption. For example, with a soil/solution ratio of 1:5 and a Kd of 20, approximately 80 % adsorption would occur.
Slovak: ads
English: Areas which are more difficult to deal with are those where the chemical is highly or very slightly adsorbed. Where low adsorption occurs, a 1:1 soil/solution ratio is recommended, although for some very organic soil types smaller ratios may be necessary to obtain a slurry. Care must be taken with the analytical methodology to measure small changes in solution concentration; otherwise the adsorption measurement will be inaccurate.
Slovak: +logAeq
English: A system of classification of solution adsorption isotherms and its use in the diagnosis of adsorption mechanisms and in measurements of pesticides surface areas of soils’. J. Chem.
Slovak: A system of classification of solution adsorption isotherms and its use in the diagnosis of adsorption mechanisms and in measurements of pesticides surface areas of soils“.
English: Check for the stability by means of parental mass balance Tier 1
Slovak: Kontrola stability v zmysle rovnováhy rodičovských hmotností
English: Equilibrium plateau is achieved?
Slovak: Dosiahlo sa rovnovážne plató? Áno
English: Adsorption kinetics
Slovak: NIE 5 vzoriek pôdy
English: In case the concentration in the aqueous phase is given on a weight/volume base then the units are ml· g-1. Kd can vary with sorbent properties and can be concentration dependent.
Slovak: V prípade koncentrácie vo vodnej fáze je daná na základe hmotnosť/objem, potom jednotky sú ml.g-1.Kd sa môže meniť s vlastnosťou sorbentu a môže byť závislé od koncentrácie.
English: As a result of partitioning between mobile and stationary phases the test substance is retarded. The dual composition of the stationary phase having polar and non-polar sites allows for interaction of polar and non-polar groups of a molecule in a similar way as is the case for organic matter in soil or sewage sludge matrices.
Slovak: Dvojité zloženie stacionárnej fázy, ktorá má polárny aj nepolárny charakter, umožňuje interakcie pólových aj nepólových skupín v molekule podobnou cestou ako v prípade organickej látky v pôdach alebo v splaškovo kalových matriciach.
English: Lowest Observed Effect Concentration (LOEC): is the lowest tested concentration at which the substance is observed to have a statistically significant effect on reproduction and parent mortality (at p < 0,05) when compared with the control, within a stated exposure period. However, all test concentrations above the LOEC must have a harmful effect equal to or greater than those observed at the LOEC. When these two conditions cannot be satisfied, a full explanation must be given for how the LOEC (and hence the NOEC) has been selected.
Slovak: Najnižšia zistená účinná koncentrácia (LOEC): je najnižšia testovaná koncentrácia, pri ktorej je badateľný štatisticky významný efekt tejto látky na reprodukciu a rodičovskú mortalitu (v p < 0,05), keď porovnávame s kontrolou v medziach stanoveného času pôsobenia.
English: At the end of the test, the total number of living offspring produced per parent animal alive at the end of the test is assessed. This means that juveniles produced by adults that die during the test are excluded from the calculations.
Slovak: Na konci testu sa odhaduje celkový počet živého potomstva vyprodukovaného rodičovským živočíchom, ktorý prežil do konca testu, to znamená, že mláďatá vyprodukované dospelými jedincami, ktorí uhynuli počas testu, sú vylúčené z výpočtov.
English: For this reason, a fully defined medium is desirable. However, at present, the only fully defined media which are known to be suitable for long-term culture of Daphnia magna are Elendt M4 and M7.
Slovak: Z tohto dôvodu sa vyžaduje úplne definované médium, v súčasnosti sú však iba Elendt M4 a M7 plne definované médiá, ktoré sú vhodné na dlhožijúce kultúry Daphnia magna.
English: For the estimation of the LOEC, and hence the NOEC, for effects of the chemical on reproductive output, it is necessary to calculate the mean reproductive output across replicates for each concentration and the pooled residual standard deviation, and this can be done using analysis of variance (ANOVA). The mean for each concentration must then be compared with the control mean using an appropriate multiple comparison method.
Slovak: Na odhad LOEC ako aj na NOEC na vplyvy chemikálií na reprodukčný výstup je potrebné vypočítať významný reprodukčný výstup cez replikáty cez každú koncentráciu a združené reziduálne štandardné odchýlky, môže sa to vykonať za použitia analýzy rozptylu (ANOVA).
English: b mean circumference of the ring (cm) σ a
Slovenian: b povprečni obseg obročka (cm)
English: DEFINITION AND UNITS The partition coefficient (P) is defined as the ratio of the equilibrium concentrations (ci) of a dissolved substance in a two-phase system consisting of two largely immiscible solvents. In the case n-octanol and water: Pow =cn-octanol cwater
Slovenian: OPREDELITVE IN ENOTE
English: A period of at least 24 hours will be allowed between the dosing of each animal. All animals should be observed for at least 14 days.
Slovenian: Med odmerjanjem za vsako žival bo dovoljeno obdobje najmanj 24 ur. Vse živali je treba opazovati najmanj 14 dni.
English: Starting dose: 300 mg/kg START 5 animals 5 mg/kg
Slovenian: 5 živali 50 mg/kg
English: 5 animals 300 mg/kg 5 animals 2000 mg/kg*
Slovenian: Začetni odmerek: 300 mg/kg
English: 5/Unclassified starting dose: 2000 mg/kg START 5 animals 5 mg/kg
Slovenian: 5 živali 5 mg/kg
English: TEST PROCEDURE WITH A STARTING DOSE OF 2000 MG/KG BODY WEIGHT Start 5 mg/kg 3 animals 50 mg/kg 3 animals
Slovenian: preskušarije pri 5000 mg/kg telesne leže: glej Prilogo 2
English: If a corrosive effect is not observed in the initial test, the irritant or negative response should be confirmed using up to two additional animals, each with one patch, for an exposure period of four hours. If an irritant effect is observed in the initial test, the confirmatory test may be conducted in a sequential manner, or by exposing two additional animals simultaneously.
Slovenian: Če se jedek učinek ne opazi v začetnem preskusu, je treba dražilni ali negativni odziv potrditi z uporabo do dveh dodatnih živali, s po enim obližem za vsako, v obdobju izpostavitve štirih ur. Če se v začetnem preskusu opazi dražilen učinek, se potrditveni preskus lahko naredi na zaporeden način ali s sočasno izpostavitvijo dveh dodatnih živali.
English: Existing human data, e.g. clinical and occupational studies, and case reports, and/or animal test data from ocular studies should be considered first, because they provide information directly related to effects on the eyes. Thereafter, available data from human and/or animal studies investigating dermal corrosion/irritation should be evaluated.
Slovenian: Najprej je treba upoštevati obstoječe podatke o ljudeh, npr. klinične ali poklicne študije in poročila o primerih, in/ali podatke preskusov na živalih, ker dajejo informacije, ki so neposredno povezane z učinki na oči.
English: If extreme pH is the basis for identifying a substance as corrosive or irritant to the eye, then its acid/alkaline reserve (buffering capacity) may also be taken into consideration (5)(6). If the buffering capacity suggests that a substance may not be corrosive to the eye, then further testing should be undertaken to confirm this, preferably by the use of a validated and accepted in vitro or ex vivo test (see Section step 5 and 6).
Slovenian: Če blažilna sposobnost nakazuje, da snov morda ni jedka za kožo, tedaj je treba opraviti nadaljnje preskušanje za potrditev le-tega, najbolje z uporabo validiranega in sprejetega preskusa in vitro ali ex vivo (glej oddelek koraka 5 in 6).