Before revision:  Here, we present a retrospective study of outcomes in patients with acute respiratory distress (n = 13,125) or pneumonia (n = 108,956) . Patients with acute respiratory distress who were taking \alpha_1-AR antagonists for other conditions had a 35\% reduced risk of requiring ventilation , and a 56\% reduced risk of ventilation and death, compared to non-users (adjusted OR = 0.41 , 95\% CI 0.17-0.81, p = 0.01).
After revision:  Here, we present a retrospective study of outcomes in patients with acute respiratory distress (n = 13,125) or pneumonia (n = 108,956) from all causes; patients who were incidentally taking \alpha-blockers had a reduced risk of requiring ventilation , and a 56\% reduced risk of ventilation and death, compared to non-users (adjusted OR = 0.41 , 95\% CI 0.17-0.81, p = 0.01).