Before revision: Characteristics In 2001, Sutton and colleagues proposed that intermediate-term memory possesses the following three characteristics: Its induction requires translation, but not transcription Its expression requires the persistent activation of protein kinase A and protein kinase C It declines completely before the onset of long-term memory Mechanism Induction Because intermediate-term memory does not involve transcription, it likely involves the translation of mRNA transcripts already present in neurons.
After revision: Characteristics In 2001, Sutton and colleagues proposed that intermediate-term memory possesses the following 3 characteristics: Its induction requires translation, but not transcription Its expression requires the persistent activation of protein kinase A and protein kinase C It declines completely before the onset of long-term memory Mechanism Induction Because intermediate-term memory does not involve transcription, it likely involves the translation of mRNA transcripts already present in neurons.