Before revision:  Our model uses a combina- tion of analytic techniques as well as computational simulations to calculate the mean-expression and noise profiles of genes regu- lated by both sRNAs and microRNAs . We find that despite very different molecular machinery and modes of action (catalytic vs stoichiometric), the mean expression levels and noise profiles of microRNA-regulated genes are almost identical to genes regu- lated by prokaryotic sRNAs.
After revision:  Our model uses a combination of analytic techniques as well as computational simulations to calculate the mean-expression and noise profiles of genes regu- lated by both sRNAs and microRNAs . We find that despite very different molecular machinery and modes of action (catalytic vs stoichiometric), the mean expression levels and noise profiles of microRNA-regulated genes are almost identical to genes regu- lated by prokaryotic sRNAs.