Before revision:  Meanwhile, the sizes of many molecular datasets are far smaller than many other datasets in typical deep learning applications , and most hyperparameter optimization (HPO) methods have not been explored in terms of their efficiencies on such small datasets in  molecular domain.
After revision:  Meanwhile, the sizes of many molecular datasets are far smaller than many other datasets in typical deep learning applications . Most hyperparameter optimization (HPO) methods have not been explored in terms of their efficiencies on such small datasets in molecular domain.