Before revision: As a comparison, an SpCas9-reverse transcriptase fusion protein is 6.3kb, which doesn't even account for the lengthened guide RNA necessary for targeting and priming the site of interest.
After revision: As a comparison, an SpCas9-reverse transcriptase fusion protein is 6.3kb, which does not even account for the lengthened guide RNA necessary for targeting and priming the site of interest.