Before revision: The first example of an artificial molecular machine (AMM) was reported in 1994, featuring a rotaxane with a ring and two different possible binding sites .300px| Kinesin walking on a microtubule is a molecular biological machine using protein domain dynamics on nanoscales .
After revision: The first example of an artificial molecular machine (AMM) was reported in 1994, featuring a rotaxane with a ring and two different possible binding sites .