Before revision: When the rare disease assumption does not hold, the unadjusted odds ratio can overestimate the relative risk, but novel methods can easily use the same data to estimate the relative risk, risk differences, base probabilities, or other quantities.
After revision: When the rare disease assumption does not hold, the unadjusted odds ratio will be greater than the relative risk, but novel methods can easily use the same data to estimate the relative risk, risk differences, base probabilities, or other quantities.