Before revision:  In this way , not only  therapies govern the evolution of different  phenotypes, but variable resistances of cells govern the evolution of  therapies as well  .
After revision:  In this way , not only therapies govern the evolution of different phenotypes, but variable resistances of cells govern the evolution of therapies as well . We illustrate the approach by the minimalistic ad hoc evolutionary model. Its results indicate that the resistant cells could bias the evolution towards more toxic elementary therapies by inhibiting the less toxic ones .