Before revision:  Our results suggest a method to select groups of functionally similar proteins even when no annotation is yet known, thereby yielding a valuable diagnostic tool to predict groups that act concertedly within the cell .
After revision:  Our results suggest a method to select groups of proteins which are likely to participate in similar biological functions. We show that high mean clustering coefficient and low mean node betweenness centrality can be used to predict functionally homogeneous communities. Availability: All the data sets and the community detection algorithm are available online .