Before revision:   For comparison purposes, we applied the Least Square Regression (LSR), Ridge Regression (RR), LASSO, non-negative LASSO (nLASSO), and the Bayesian approaches to four public data sets which have the known interaction pairs of miRNA and mRNA. Comparing to the point estimate algorithms,  the Bayesian methods are able to infer more known interactions and are more meaningful to provide credible intervals to take into account the uncertainty of the interactions of miRNA and mRNA.
After revision:  For comparison purposes, we applied the Least Square Regression (LSR), Ridge Regression (RR), LASSO, non-negative LASSO (nLASSO), and the Bayesian approaches to four public datasets. We concluded that nLASSO and nBLASSO perform best in terms of sensitivity and specificity. Compared to the point estimate algorithms, the Bayesian methods are able to infer more known interactions and are more meaningful to provide credible intervals to take into account the uncertainty of the interactions of miRNA and mRNA.