Before revision: The adductome is the totality of chemical adducts that may arise from the chemical reaction between any xenobiotic (or indeed endogenous) substance to which an organism is exposed (sometimes referred to as the "exposome") and macromolecules such as DNA, and RNA, or proteins found within the organism.
After revision: The adductome is the totality of chemical adducts that may arise from the chemical reaction between any xenobiotic substance to which an organism is exposed (sometimes referred to as the "exposome") and macromolecules such as DNA, and RNA, or proteins found within the organism.