Before revision: Improvisation of ACI Techniques such as the EELS-TALC to enhance ACI and MACI with enabling chondrocytes to be tissue engineered with long term native knee cartilage phenotype maintenance in vitro and in vivo, with the engineered tissue construct containing stem cell progenitors along with those expressing pluripotency markers and with added advantage of enriched hyaluronic acid (HA) expression by the cells have been reported which will contribute to improvised regenerative therapies for cartilage damage.
After revision: Improvisation of ACI Techniques such as the EELS-TALC to enhance ACI and its next generation advancement called Matrix Assisted Chondrocyte Implantation (MACI) with enabling chondrocytes to be tissue engineered with long term native knee cartilage phenotype maintenance in vitro and in vivo, with the engineered tissue construct containing stem cell progenitors along with those expressing pluripotency markers and with added advantage of enriched hyaluronic acid (HA) expression by the cells have been reported which will contribute to improvised regenerative therapies for cartilage damage.