Before revision: Biochemical networks, under mass-action kinetics, containing reactions with three or more reactants (called high-molecular reactions) are investigated. An algorithm for stochastically approximating the high-molecular reactions with a set of bi-molecular ones, involving at most two reactants, is presented.
After revision: Biochemical networks, under mass-action kinetics, containing reactions with three or more reactants , called higher-molecular reactions, play an important role in theoretical systems and synthetic biology. In particular, such reactions underpin a variety of important bio-dynamical phenomena, such as multi-stability/multi-modality, oscillations, bifurcations, and noise-induced effects. However, only reactions with at most two reactants, is presented.