Before revision:  Towards this end, the recently developed two-moment approximation (2MA) is a promising approach, accounting for the coupling between the means and ( co)variances.
After revision:  Towards this end, the recently developed two-moment approximation (2MA) is a promising addition to the established analytical approaches including the chemical Langevin equation (CLE) and the related linear noise approximation (LNA). The 2MA approach directly tracks the mean and ( co)variances.