Before revision:  Since functional status and structural properties are often intertwined, in this work we look at the structural properties of URLanelle in normal mouse embryonic fibroblasts , describing its most relevant features . Subsequently we manipulated mitochondrial morphology using two interventions with opposite effects: over-expression of mitofusin 1, a protein that promotes mitochondria fusion , and paraquat treatment, a compound that induces mitochondrial fragmentation due to oxidative stress . Quantitative analysis of URLanelle's structural clusters revealed that healthy mitochondrial networks were in a status intermediate between the extremes of highly fragmented and completely fusioned networks.
After revision:  Since functional status and structural properties are often intertwined, in this work we look at the structural properties of URLanelle in normal mouse embryonic fibroblasts , describing its most relevant features . Subsequently we perturbed the system either by promoting the fusion of mitochondrial segments or by inducing mitochondrial fission . Quantitative analysis of URLanelle's structural clusters revealed that healthy mitochondrial networks were in a status intermediate between the extremes of highly fragmented and completely fusioned networks.