Before revision: Assuming that mutation and fixation processes are reversible Markov processes, we prove that the equilibrium ensemble of sequences obeys a Boltzmann distribution with \exp(4N_e m(1 - 1/(2N))), where m is a Malthusian fitness and N_e and N are the effective and actual population sizes.
After revision: Assuming that mutation and fixation processes are reversible Markov processes, we prove that the equilibrium ensemble of sequences obeys a Boltzmann distribution with \exp(4N_e m(1 - 1/(2N))), where m is a Malthusian fitness and N_e and N are effective and actual population sizes.