Before revision:  Incorporating this catchbonding behavior of dynein in a theoretical model and using experimentally relevant measures characterizing cargo transport , we show that the functional divergence of the two motors species manifests itself as an internal regulatory mechanism for bidirectional transport and resolves the paradox of codependence.
After revision:  Incorporating this catchbonding behavior of dynein in a theoretical model , we show that the functional divergence of the two motors species manifests itself as an internal regulatory mechanism for bidirectional transport and resolves the paradox of codependence.