Before revision:   We find that when the method is properly applied, variance reductions by factors in the thousands can be obtained.
After revision:  The task is to estimate the expectation of a function of molecule copy numbers at a given future time T by the sample average over n sample paths, and the goal is to reduce the variance of this sample-average estimator. We find that when the method is properly applied, variance reductions by factors in the thousands can be obtained.