Before revision:  But at what level do measurements made by cellular systems map onto computational measurements made, for example, by magnetic devices ? Can cells reach the thermodynamic limit of minimal dissipation for a given measurement accuracy, and , if not, what is the cause? We consider a canonical biochemical network that reads out the state of a receptor and show rigorously how it relates to a measurement protocol of the type studied in the computational literature.
After revision:  But at what level do measurements made by cellular systems map onto computational measurements made, for example, by magnetic devices ? Can cells reach the thermodynamic limit of minimal dissipation for a given measurement accuracy, and , if not, why? We show that, as in computation, a canonical biochemical network that reads out the state of a receptor and show rigorously how it relates to a measurement protocol of the type studied in the computational literature.