Before revision:  The same approach also yields the potential of mean-force for reaction coordinates, the reaction rate and transition path time. For illustration and validation purposes, we test this method against the results of protein folding MDsimulations which were obtained on the Anton supercomputer, using the same all-atom force field  .
After revision:  We test this method against the results of protein folding MDsimulations which were obtained on the Anton supercomputer, using the same all-atom force field .