Before revision:  in the probability distributions of noise, we find that the fluctuations in the synthesis reaction rate lead to peculiar transitions to high concentrations and thus to possible transcriptions, such as realizing higher likelihood of transcription for larger positive skewness (i.e., asymmetry)
After revision:  in the probability distributions of noise, we find that the fluctuations in the synthesis reaction rate lead to peculiar likelihood for transcription. This includes, in the additive noise case, realizing higher likelihood of transcription for larger positive skewness (i.e., asymmetry)