Before revision:  DDD movies of the\textit{Saccharomyces cerevisiae V-ATPase are used to demonstrate that the algorithm is able to produce physically reasonable trajectories for a 900 kDa membrane protein complex .
After revision:  DDD movies of the\textit{Saccharomyces cerevisiae This individual particle motion correction, in combination with weighting of Fourier components to account for increasing radiation damage in later frames, can be used to improve 3-D maps from single particle cryo-EM .