Before revision: AQPs (aquaporins), the rapid water channels of cells, play a key role in maintaining osmotic equilibrium of cells. In this paper, we reported the dynamic mechanism of AQP osmosis at the molecular level. A theoretical model based on molecular dynamics was carried out and verified by the published experimental data. The reflection coefficients ( \sigma ) of neutral molecules are mainly decided by their relative size with AQPs, and increase with a third power up to a constant value 1.
After revision:  \sigma ) of neutral molecules are mainly decided by their relative size with AQPs, and increase with a third power up to a constant value 1.