Before revision: This functional ratio change is mediated by a decrease in myometrial sensitivity to progesterone, due to an increase (surely this should be decrease ) in progesterone receptor A, and a concurrent increase in myometrial sensitivity to estrogen, due to an increase in estrogen receptor α.
After revision: This functional ratio change is mediated by a decrease in myometrial sensitivity to progesterone, due to a decrease in progesterone receptor A, and a concurrent increase in myometrial sensitivity to estrogen, due to an increase in estrogen receptor α.