Before revision: Phosphoanhydride Bond Formation While early studies of phosphorimidazolide derivatives of nucleotides found that oligonucleotides could form in the presence of a complimentary template, pyrophosphate-linked dimers formed predominantly in the absence of a template.
After revision: Phosphoanhydride Bond formation While early studies of phosphorimidazolide derivatives of nucleotides found that oligonucleotides could form in the presence of a complimentary template, pyrophosphate-linked dimers formed predominantly in the absence of a template.