Before revision: Synaptic tagging, or the synaptic tagging hypothesis, was first proposed in 1997 by Julietta U. Frey (her publishing name was Uwe Frey or J. U. Frey before the year 2000 URL and Richard G. Morris; it seeks to explain how neural signaling at a particular synapse creates a target for subsequent plasticity-related product (PRP) trafficking essential for sustained LTP and LTD.
After revision: Synaptic tagging, or the synaptic tagging hypothesis, has been proposed to explain how neural signaling at a particular synapse creates a target for subsequent plasticity-related product (PRP) trafficking essential for sustained LTP and LTD.