Before revision:  Here we study the physical mechanism of the reversible mechanosensor of the 2nd kind, using FAK as a practical example , and find how the rates of conformation changes depend on the substrate stiffness and the pulling force applied from the cell cytoskeleton.
After revision:  Here we study the physical mechanism of the reversible mechanosensor of the 2nd kind, using FAK as a practical example . We find how the rates of conformation changes depend on the substrate stiffness and the pulling force applied from the cell cytoskeleton.