Before revision:  Here, we have developed a multi-scale model of bacterial DNA replication coupled to cell division in the context of a logistically growing population. DNA replication is modeled as the stochastic dynamics of replication forks (RFs) which transition probabilistically between two states, stalled and recovered. In the model stalled RFs or incomplete DNA replication results in aberrant cell division.
After revision:  Here, we have developed a population dynamics model of individual cell division based on the BCD, birth, chromosome replication and division model, with DNA replication based on the Cooper and Helmstetter (CH) multi-fork replication. In our model, stochasticity in the model arises solely from the dynamics of DNA replication forks. We model the model stalled RFs or incomplete DNA replication results in aberrant cell division.