Before revision:  We use B-DNA as our prototype system , where all sequences have purines  on the same strand and start with guanine.We investigate the interplay between structure, magnitude of parameters , and spectral, localization and charge transport properties.
After revision:  We use B-DNA as our prototype system , where all sequences have purines on the same strand , i.e., our prototype binary alphabet is (G,A). Our aim is to examine the influence of sequence intricacy and magnitude of parameters , and spectral, localization and charge transport properties.