Before revision:  We were able to identify distinct increases in negative sentiment , theory-specific trends in geospatial spread, and the evolution of conspiracy theory topics and subtopics over time. Conclusions: COVID-19 related conspiracy theories show that history frequently repeats itself, with the same conspiracy theories being recycled for new situations. We use a combination of supervised learning, unsupervised learning, and natural language processing techniques to look at the evolution of theories over the first four months of the COVID-19 outbreak, how these theories intertwine, and to hypothesize on more effective public health messaging to combat misinformation in online spaces .
After revision:  We were able to identify distinct increases in negative sentiment , incorporating details from unrelated conspiracy theories as well as real-world events. Conclusions: Although we focus here on health-related misinformation, this combination of approaches is not specific to public health and is valuable for characterizing misinformation in general, which is an important first step in creating targeted messaging to counteract its spread. Initial messaging should aim to preempt generalized misinformation before it becomes widespread, while later messaging will need to target evolving conspiracy theories and the new facets of each as they become incorporated .