Before revision:  In accordance with the standard model of LD formation, we assumed that neutral lipids oil-out between the membrane leaflets of the endoplasmic reticulum (ER), resulting in LDs that bud-off when a critical size is reached.
After revision:  In accordance with the prevailing model of LD formation, we assumed that neutral lipids oil-out between the membrane leaflets of the endoplasmic reticulum (ER), resulting in LDs that bud-off when a critical size is reached.