Before revision:  However, one of the current limitations compared to statistical and traditional machine learning approaches is the lack of explainability, which not only reduces the reliability, but limits the potential for acquiring novel knowledge from unpicking the " black-box "  models.
After revision:  However, one of the current limitations compared to statistical and traditional machine learning approaches is the lack of explainability, which not only reduces the reliability, but limits the potential for acquiring novel knowledge from unpicking the " black-box " problem can undermine the credibility and limit the practical implementation of biomedical deep learning models.