Before revision:  We provide experimental evidence suggestive of its presence in DNA. Asymmetric cooperativity is used to explain, apart from the broken symmetries mentioned above, a number of other properties of DNA that includes four nucleotide alphabet, three nucleotide codons,  helicity, anti-parallel double-strand orientation, heteromolecular base-pairing, asymmetric base compositions, and palindromic instability  .
After revision:  We provide experimental evidence suggestive of its presence in DNA. Asymmetric cooperativity is used to explain, apart from the broken symmetries mentioned above, a number of other properties of DNA that includes four nucleotide alphabet, three nucleotide codons, helicity, anti-parallel double-strand orientation, heteromolecular base-pairing, asymmetric base compositions, and palindromic instability , apart from the structural asymmetries mentioned above. Our model results and explanations are consistent with multiple lines of experimental evidence, which include evidence for the presence of asymmetric cooperativity in DNA .