Before revision:  This relation is used here to solve the inverse problem of constructing a GEM which best reproduces the contact probabilities measured experimentally. For that purpose, we present a minimization scheme that searches for the GEM that has contact probabilities as close as possible to the experimental ones. We apply this method to several data sets generated from experiments using the Hi-C or GAM techniques.
After revision:  This relation is used here to solve the inverse problem of constructing a GEM which best reproduces the contact probabilities measured in Hi-C or GAM techniques.