Before revision: We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built only uponknown biomolecular interactions in the system ,a posteriori identifying the key ones necessary for bistability of epigenetic states.
After revision: We introduce and analyze a minimal model of epigenetic silencing in budding yeast, built only uponknown biomolecular interactions in the system ,a posteriori . Doing so, we identify the epigenetic marks essential for the bistability of epigenetic states.