Before revision:  This  framework is very general and can be used to model a variety of problems , such as pharmaceutical companies choosing drugs to develop , studios selecting movies to produce , or our focus in this work, which is venture capital firms picking startup companies in which to invest. We first frame the construction of a  portfolio as a combinatorial optimization problem with objective function given by the probability of having at least one item in the selected portfolio win.
After revision:  This framework is very general and can be used to model a variety of problems , such as pharmaceutical companies choosing drugs to develop , studios selecting movies to produce . We frame the construction of a portfolio as a combinatorial optimization problem with objective function given by the probability of having at least one item in the selected portfolio win.