Before revision:  By reliably and rapidly narrowing down target interactions,  our predictions can inform and reduce the time spent on more computationally intensive in-silico analyses, and time-consuming in-vitro and in-vivo experiments  .
After revision:  By reliably and rapidly narrowing down target interactions, our predictions can inform and reduce the time spent on more computationally intensive in-silico analyses, and time-consuming in-vitro and in-vivo experiments , or more computationally intensive in-silico analyses .