Before revision:  However, these methods mainly assume multiple regions as one vast uniform region or several independent regions, ignoring connections among them .
After revision:  However, the critical assumption in these methods is that a priori different brain regions respond the same way to all the stimuli, that is, there is no modularity or specialization assumed for any region. This goes against the modularity theory, supported by many cognitive neuroscience investigations suggesting that there are functionally specialized regions in the brain .