Before revision:  For methodology, with  Principal component analysis technique, 22 variables in socioeconomic data related to the continuous use of opioid drugs was filtered, where the 'Relationship' Part deserves  highlight.
After revision:  For methodology, with Principal component analysis technique, 22 variables in socio-economic data related to the continuous use of opioid drugs was filtered, where the 'Relationship' Part deserves highlight.