Before revision:  In this study, we have taken a computational approach to examine how an anti-ABeta antibody binds to one or more ABeta epitopes in its antigen-combining site. Our unbiased fragment-based docking method successfully predicted the emergence of the key EFRH epitopecommonly observed when ABeta binds to anti-ABeta antibodies.
After revision:  In this study, we have taken a computational approach to examine how an anti-ABeta antibodies for rational drug design efforts. Our fragment-based docking method successfully predicted the emergence of the key EFRH epitopecommonly observed when ABeta binds to anti-ABeta antibodies.