Before revision:  Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations , considering the huge number of possible disease mutations. The most important drawback of GWAS analysis in addition to its high cost  is the large number of false-positives.
After revision:  Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations , considering the huge number of possible mutations, in addition to its high cost is the large number of false-positives.