Before revision: Using our recent contribution, the "  partitioned leaping algorithm"  [L. A. Harris and P. Clancy, J. Chem.
After revision: Using our recent contribution, the " Leaping" methods show great promise for significantly accelerating stochastic simulations of complex biochemical reaction networks. However, few practical applications of leaping have appeared in the literature to date. Here, we address this issue using the " partitioned leaping algorithm" [L. A. Harris and P. Clancy, J. Chem.