Before revision:  While binding dominance is inevitable at the molecular level, it may be difficult to detect in the phenotype under some biophysical conditions, more so when TF concentration is high and allele-specific binding affinities are similar.
After revision:  While binding dominance is inevitable at the molecular level, it may be difficult to detect in the phenotype under some biophysical conditions, more so when TF dosage is high and allele-specific binding affinities are similar.