Before revision:  Computational models predict that an interplay between noise and spike-frequency adaptation can yield a transition from sleep-like to anesthesia-like slow-wave dynamics. These predictions were confirmed by pharmacological manipulations in vitro , inducing a switch between the two types of slow-waves.
After revision:  Computational models predict that an interplay between noise and spike-frequency adaptation in excitatory cells can account for dynamical distinctions between the two types. This prediction was tested in vitro by varying adaptation strength using an agonist of acetylcholine receptors, which demonstrated a neuromodulatory switch between the two types of slow-waves.