Before revision:  For 32 of 40 loops that challenged prior approaches, at least one of five lowest energy SWA models agrees with the crystallographic conformation with C \alpha RMSD accuracy better than 1.0 \AA . SWA successes include hairpin-like loops , cis-Pro touch turns, loops with lengths of up to 24 residues (well outside the range of previous methods), and five blind tests:
After revision:  For 32 of 40 loops that challenged prior approaches, at least one of five lowest energy SWA models agrees with the crystallographic conformation with C \alpha RMSD accuracy better than 1.0 \AA enables enumerative sampling of a 12 residue loop at a significant but achievable cost of thousands of CPU-hours. In a previously established benchmark, SWA recovers crystallographic conformations with sub-Angstrom accuracy for 19 of 20 loops, compared to 14 of 20 by KIC modeling with a comparable expenditure of computational power. Furthermore, SWA gives high accuracy results on an additional set of 15 loops highlighted in the biological literature for their irregularity or unusual length. Successes include cis-Pro touch turns, loops with lengths of up to 24 residues (well outside the range of previous methods), and five blind tests: