Before revision: While there has been an explosion in the number of experimentally determined, atomically detailed structures of proteins, how to represent these structures in a machine learning context remains an open research question.
After revision: While there has been an explosion in the number of experimentally determined, atomically detailed structures of biomolecules, many critical tasks in structural biology remain data-limited. Whether performance in such tasks can be improved by using large repositories of tangentially related structural data remains an open research question.