Before revision: The function of proteins is determined by a combination of their structure and dynamics. Acquisition of structural information has recently been revolutionized by advances in electron microscopy, however protein dynamics is difficult to obtain over long timescales. Here we show a novel plasmon ruler based single molecule approach to study the conformational dynamics of single proteins over 24 hours at video rate in and out of equilibrium (i. e. in the absence and presence of ATP).
After revision: We use plasmon rulers to follow the conformational dynamics of single proteins over 24 hours at video rate in and out of equilibrium (i. e. in the absence and presence of ATP).