Before revision:  In this study, we adapt a recent model of pacemaker cells (Severi et al., 2012), incorporating biophysical representations of ion channel and intracellular calcium dynamics, to capture physiological features of a heterogeneous population of pacemaker cells , in particular "center" and "peripheral" cells with distinct intrinsic frequencies and action potential morphology.
After revision:  In this study, we adapt a recent model of pacemaker cells (Severi et al., 2012), incorporating biophysical representations of ion channel and intracellular calcium dynamics, to capture physiological features of a heterogeneous population of pacemaker cells ; in particular "center" and "peripheral" cells with distinct intrinsic frequencies and action potential morphology.