Before revision: Causes This condition is caused by a mutation in the ACO2 URL located on chromosome 22q13.2
After revision: , normally, this gene produces a protein/enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle.Causes This condition is caused by a mutation in the ACO2 URL located on chromosome 22q13.2