Before revision:  During pluripotency , miRNAs primarily repress developmental processes while they inhibit metabolism in the differential state. Interestingly, in the pluripotent state, miRNAs do not directly regulate the pluripotent core activities but mediate extrinsic signal pathways associated with the pluripotency;
After revision:  During pluripotency , miRNAs primarily repress developmental processes , but surprisingly miRNAs do not directly regulate the pluripotent core activities but mediate extrinsic signal pathways associated with the pluripotency;