Before revision:  This study addresses this issue by developing a computational algorithm to determine pulmonary hemodynamics ( blood pressure and flow ) in a large network of arterial vessels and subsequently quantify the uncertainty of these predictionsto geometric variation associated with image segmentation. We introduce uncertainty in the blood vessel network by generating multiple segmentations of a pulmonary tree from a single image of an excised mouse lung using randomly selected pre-segmentation parameters.
After revision:  This study addresses this issue by developing a computational algorithm to determine pulmonary hemodynamics ( blood pressure and flow predictions. We analyse multiple segmentations of a pulmonary tree from a single image of an excised mouse lung using randomly selected pre-segmentation parameters.