Before revision:  Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed a priori known , the evolution of the genetic composition of a population does not affect demography nor population structure, and there is no selection nor interaction between and within genetic strains.
After revision:  Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed a priori known , the evolution of the genetic composition of a population does not affect demography nor population structure, and there is no selection nor interaction between and within genetic strains.