Before revision:   Volume change and advective solute transport varies with the phase of muscle stimulation during periodic contraction but remains significant at all conditions . Nonetheless, advective transport varies will occur in all cases where the sarcomere is not isovolumetric .
After revision:  Lattice spacing depends on a variety of factors that produce radial force, including crossbridges, titin-like molecules, and other structural proteins. Volume change and advective solute transport varies with the phase of muscle stimulation during periodic contraction but remains significant at all conditions . Nonetheless, advective transport varies will occur in all cases where the sarcomere is not isovolumetric .