Before revision: Transfection of the SV40 large T antigen oncogene can transiently induce apoptosis, nuclear translocation, and apoptin phosphorylation in normal cells, showing that apoptin can detect early oncogenic change.
After revision: Transfection of the SV40 large T antigen oncogene can rapidly, albeit transiently, induce apoptosis, nuclear translocation, and apoptin phosphorylation in normal cells, showing that apoptin can detect early oncogenic change.