Before revision:  We show that the core of the cellular autocatalytic network is the transcription-translation machinery which by itself is an autocatalytic network composed of several coupled autocatalytic cycles like ribosome, RNA-polymerase and tRNA charging cycles.
After revision:  We show that the core of the cellular autocatalytic network is the transcription--translation machinery -- in itself an autocatalytic network composed of several coupled autocatalytic cycles like ribosome, RNA-polymerase and tRNA charging cycles.