Before revision:  A common class of such receptors are G-protein coupled receptors, where extracellular binding induces changes in the membrane affinity near the receptor for certain diffusible cytosolic proteins, effectively altering their chemical potential.
After revision:  A common class of such receptors are G-protein coupled receptors, where extracellular binding induces changes on the membrane affinity near the receptor for certain diffusible cytosolic proteins, effectively altering their chemical potential.