Before revision: Pluripotency is the defining characteristic of human embryonic stem cells (hESCs) allowing them to differentiate into any somatic cell in the human body. For the promising clinical applications of hESCs, improved regulation of pluripotency and differentiation trajectories of their colonies is required .
After revision: Pluripotency is the defining characteristic of human embryonic stem cell (hESC) pluripotency and differentiation trajectories of their colonies is required .