Before revision:  SUM149 /TIME platformswere 1.3 fold lower (p<0.05) , and MDA-MB-231 /TIME platforms were 1.5 fold lower (p< 0.01) in endothelial coverage compared to the control TIME only platform. HER2+ MDA-IBC3 tumor cells expressed high levels of VEGF (p<0.01) and induced vessel sprouting.
After revision:  SUM149 /TIME platformswere 1.3 fold lower (p<0.05) , and MDA-MB-231 /TIME platforms were 1.5 fold lower (p< 0.05) and control (p<0.01) and induced vessel sprouting.