Before revision:  In this study, mice spinal cords from the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS) were investigated for the first time using this modality in combination with biophysical modeling to reveal the relationship between microstructural metrics and clinical disability. Thirteen EAE spinal cords of variable disability were extracted, dissected and subsequently scanned in a high-field MRI scanner along with 5 control specimen.
After revision:  In this study, mice spinal cords from the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS) were investigated for the first time using this modality in combination with biophysical modeling to reveal the relationship between microstructural metrics and degree of animal dysfunction. Thirteen spinal cords were extracted from animals of variable disability were extracted, dissected and subsequently scanned in a high-field MRI scanner along with 5 control specimen.