Before revision:  We used this technique to explore the dynamics of the  heat shock protein 90 (Hsp90) and find (beside the well-known fast dynamics in the range netween 0.1 and 10 s) states with very long dwell times (linked to rarely visited states) in the minute timescale, which could indicate, for instance, pathways to protein denaturation.
After revision:  We used this technique to explore the dynamics of the molecular chaperone heat shock protein 90 (Hsp90) and find (beside the well-known fast dynamics in the range netween 0.1 and 10 s) states with very long dwell times (linked to rarely visited states) in the minute timescale, which could indicate, for instance, pathways to protein denaturation.