Before revision:  In this study, we show that the RNAP-II based reinitiation process in gene expression can increase or decrease the mean and Fano factor both at the mRNA levels and therefore, can have important contributions on cellular functions .
After revision:  In this study, we show that the RNAP-II based reinitiation process in gene transcription can have different effects on both mean and Fano factor at mRNA levels in different model systems. It decreases the mean and Fano factor both at the mRNA levels and therefore, can have important contributions on cellular functions .