Before revision: Deformable registration of clinical scans is a fundamental task for many applications, such as population studies or the monitoring of long-term disease progression in individual patients. This task is challenging because, in contrast to high-resolution research-quality scans, clinical images are often sparse, missing up to 85\% of the slices in comparison.
After revision: Deformable registration of clinical scans is a fundamental task for many medical image applications such as longitudinal population studies. Most registration algorithms are designed for high-resolution research-quality scans and under-perform when applied to clinical data. Clinical scans present unique challenges because, in contrast to high-resolution research-quality scans, clinical images are often sparse, missing up to 85\% of the slices in comparison.