Before revision:  Relying on this mechanism, we have calculated the change in the elastic free energy of the membrane caused by nascent LDs. We found a gradual de-mixing of lipids in the membrane leaflet that goes along with an increase in surface curvature at the site of LD formation.
After revision:  Relying on this mechanism, we have calculated the change in the elastic free energy of the membrane caused by nascent LD. Based on this model calculation, we found a gradual de-mixing of lipids in the membrane leaflet that goes along with an increase in surface curvature at the site of LD formation.