Before revision:  The atlases are generated by the geometric method and curated opensource software EASAL (efficient atlasing and search of assembly landscapes), whose input consists of (a) the monomer geometry - atom coordinates; and for each interface type, (b) pair potentials for a candidate set of interactions along with Van der Waals sterics, and (c) structure of selected, small subassemblies. The method comes with rigorous accuracy-efficiency trade-off estimates. A second two-scale measure of cruciality of interactions and residues for capsid assembly is obtained as follows. Combinatorial entropy is used to define the cruciality of an interface for successful assembly of the capsid.
After revision:  The atlases are generated by the geometric method and curated opensource software EASAL . At the capsid-scale, combinatorial entropy is used to define the cruciality of an interface for successful assembly of the capsid.