Before revision:  We propose that this memory B cell selection process may be a heuristic solution to two expected risk optimization problems: optimizing for affinity to similar antigens in the future despite mutations or other minor differences, and optimizing to warm start the generation of plasma B cells in the future.
After revision:  We propose that this memory B cell selection process may be an approximate solution to two expected risk optimization problems: optimizing for affinity to similar antigens in the future despite mutations or other minor differences, and optimizing to warm start the generation of plasma B cells in the future.