Before revision:  Generally, miRNAs vary their physical targets and functions with the switch of pluripotency to differentiation state. During pluripotency miRNAs primarily and mechanistically target and repress developmental processes, but surprisingly  miRNAs do not directly target the pluripotent core factors but only mediate extrinsic signal pathways associated with pluripotency.
After revision:  Generally, miRNAs primarily repress developmental processes, but surprisingly miRNAs do not directly target the pluripotent core factors but only mediate extrinsic signal pathways associated with pluripotency.