Before revision:  For 32 of 40 loops that challenged prior approaches, at least one of five lowest energy SWA models agrees with the crystallographic conformation with C \alpha RMSD accuracy better than 1.0 \AA . SWA successes include hairpin-like loops , cis-Pro touch turns, loops with lengths of up to 24 residues (well outside the range of previous methods), and five blind tests: all four loops of an unreleased 275-residue protein structure and an RNA-binding loop of YbxF, a target in the fourth RNA-puzzle competition.
After revision:  For 32 of 40 loops that challenged prior approaches, at least one of five lowest energy SWA models agrees with the crystallographic conformation with C \alpha RMSD accuracy better than 1.0 \AA . SWA successes include hairpin-like loops , cis-Pro touch turns, loops with lengths of up to 24 residues . Remaining problem cases are traced to inaccuracies in the Rosetta all-atom energy function. In five additional blind tests, SWA achieves sub-Angstrom accuracy models, including the first such success in a protein/RNA binding interface, the YbxF/kink-turn interaction in the fourth RNA-puzzle competition.