Before revision: Since light field microscopy captures full volume information in a single frame, it is possible to monitor neural activity in individual neurons randomly distributed in a large volume at video framerate.Grosenick, 2009, 2017; Perez, 2015 Quantitative measurement of neural activity can be done despite optical aberrations in brain tissue and without reconstructing a volume image,Pegard, 2016 and be used to monitor activity in thousands of neurons.Grosenick, 2017 Generalized Scene Reconstruction (GSR)–This is a method of 3D reconstruction from multiple images that creates a scene model representing a generalized light field and a relightable matter field.Leffingwell, 2018 The light field represents light flowing in every direction through every point in the scene.
After revision: Since light field microscopy captures full volume information in a single frame, it is possible to monitor neural activity in individual neurons randomly distributed in a large volume at video framerate.Grosenick, 2009, 2017; Perez, 2015 Quantitative measurement of neural activity can be done despite optical aberrations in brain tissue and without reconstructing a volume image,Pegard, 2016 and be used to monitor activity in thousands of neurons.Grosenick, 2017 Generalized Scene Reconstruction (GSR)–This is a method of 3D reconstruction from multiple images that creates a scene model comprisinggeneralized a generalized light field and a relightable matter field.Leffingwell, 2018 The light field represents light flowing in every direction through every point in the scene.