Before revision: Transcriptome-wide association study (TWAS) is a statistical genetics methodology to improve detection power and provide functional annotation for genetic associations with phenotypes by integrating single-nucleotide polymorphism to trait (SNP-trait)associations from genome-wide association studies with SNP-based prediction models of gene expression.
After revision: Transcriptome-wide association studyTranscriptome-wide association study (TWAS) is a statistical genetics methodology to improve detection power and provide functional annotation for genetic associations with phenotypes by integrating single-nucleotide polymorphism to trait (SNP-trait)associations from genome-wide association studies with SNP-based prediction models of gene expression.