Before revision:  Additionally, there has been a growing interest in the systematic comparison of multiple networks to identify deferentially changed links. Typically, such analyses are focused on the comparison of networks or data from two different conditions. Results: Here, we present an R package for calculating the weighted topological overlap (wTO), that explicitly addresses the sign of wTO values .
After revision:  Here, we present an R package for calculating the weighted topological overlap (wTO), that explicitly addresses the sign of wTO values .