Before revision:  The model serves as an elementary "building block" towards understanding more complex cross-wired receptor-ligand signaling networks , and suggests how cross-talk and pleiotropy might be inherent features of combinatorial signaling in cross-wired networks. The results of the paper suggest a novel outlook at a number of experimental systems .
After revision:  The model serves as an elementary "building block" towards understanding more complex cross-wired receptor-ligand signaling networks .