Before revision:  The hydration thermodynamics of g-butane or the conditional hydration thermodynamics of isoleucine from the GGIGG pentapeptide proves unsatisfactory in predicting the properties of either IGGGG or the isoleucine-substituted helical deca-peptides .
After revision:  The hydration thermodynamics of g-butane model are also more negative than the corresponding conditional quantities for the side-chain. The conditional solvation of isoleucine in GGIGG also proves unsatisfactory in predicting the properties of either IGGGG or the isoleucine-substituted helical deca-peptides .