Before revision:  We find that regardless of the network parameters , the biochemical network can never reach the thermodynamic limit of efficiency, and faces a tradeoff between accuracy and dissipation that is more severe than and qualitatively distinct from the tradeoff required thermodynamically .
After revision:  We find that regardless of the network parameters , the biochemical network cannot reach this bound, even with arbitrarily slow reactions or weak thermodynamic driving. It faces an accuracy-dissipation trade-off that is qualitatively distinct from the tradeoff required thermodynamically .