Before revision: The adductome is the totality of chemical adducts that arise from the chemical reaction between any xenobiotic substance that an organism is exposed to (sometimes referred to as the "exposome") and macromolecules such as DNA, and RNA, or proteins found within the organism.
After revision: The adductome is the totality of chemical adducts that arise from the chemical reaction between any xenobiotic (or indeed endogenous) substance to which an organism is exposed may (sometimes referred to as the "exposome") and macromolecules such as DNA, and RNA, or proteins found within the organism.