Before revision:  Our predictions imply that low-affinity binding scores, usually wasted in protein-protein and protein-DNA docking algorithms, can be efficiently utilized to compute the free energy  .
After revision:  Our predictions imply that low-affinity binding scores, usually wasted in protein-protein and protein-DNA docking algorithms, can be efficiently utilized to compute the free energy . Using the results of Rosetta docking simulations of protein-protein interactions from Andre et al., Proc. Natl. Acad. Sci. U.S.A. 105, 16148 (2008), we demonstrate the power of our predictions .