Before revision:  The Kramers rate formula to estimate the transition times from the unfolded to the native-like states shows that these times are in reasonable agreement with the corresponding times obtained in the simulations and may be far shorter than the MFPTs to reach the native state  .
After revision:  The Kramers rate formula to estimate the transition times from the unfolded to the native-like states shows that these times are in reasonable agreement with the corresponding times obtained in the simulations and may be far shorter than the MFPTs to reach the native state . The time to find the native state among native-like ones increases with temperature, which explains the known U-shape dependence of the MFPTs on temperature .