Before revision:  Combining previous knowledge about the fate specification induced by asymmetric division and the anti-correlation between cell cycle length and cell volume  , we propose a model to simulate lineage  by altering cell volume segregation ratio in each division, and quantify the derived lineage 's performance in proliferation rapidity , fate diversity and space robustness (PFS Model) .
After revision:  Combining previous knowledge about the fate specification induced by asymmetric division and the anti-correlation between cell cycle length and cell volume , we propose a model to simulate lineage initiation by altering cell volume segregation ratio in each division, and quantify the derived lineage 's performance in proliferation rapidity , fate diversity and space robustness (PFS Model) .