Before revision: DNA binding domain of QF2 fused with VP16 transcriptional activator domain was successfully applied in Penicillium to gain control over the Penicillin producing secondary metabolite gene cluster with a scalable manner.
After revision: DNA binding domain of QF2 fused with VP16 transcriptional activator domain was successfully applied in Penicillium to gain control over the penicillin producing secondary metabolite gene cluster in a scalable manner.