Before revision: Transfection of the SV40 large T antigen oncogene into noncancerous cells can rapidly, albeit transiently, induce apoptosis, nuclear translocation , and apoptin phosphorylation in normal cells, showing that apoptin can detect early oncogenic change.
After revision: Transfection of the SV40 large T antigen oncogene into noncancerous cells can rapidly, albeit transiently, induce the phosphorylation and nuclear translocation of apoptin in normal cells, showing that apoptin can detect early oncogenic change.