Before revision: RNA genes are ubiquitous in cell physiology, with a diverse repertoire of known functions. In fact, the majority of the eukaryotic genome does not code for proteins, and thousands of conserved RNAs of currently unknown function have been identified . Knowledge of 3D structure could can help elucidate the function of these RNAs but despite outstanding word using X-ray crystallography, NMR and cryoEM, structure determination remains low-throughput.
After revision: RNA genes are ubiquitous in cell physiology, but the vast majority of non-coding RNAs are poorly understood . Knowledge of 3D structure could can help elucidate the function of these RNAs but despite outstanding word using X-ray crystallography, NMR and cryoEM, structure determination remains low-throughput.