Before revision:  Mean curvature of schizophrenia cases was approximately 1.5 -times as high as that of controls .
After revision:  Mean curvature of schizophrenia cases was approximately 1.5 times higher than that of the controls. A schizophrenia case carrying a frame shift mutation in the GLO1 gene showed the highest neurite curvature, suggesting that oxidative stress due to the GLO1 mutation caused the structural alteration of the neurites. The differences in the neurite curvature result in differences in the spatial trajectory and hence alter neuronal circuits .