Before revision:  Our data show that telosomes predominantly restrict both MRE11  and  mre11A470T telosomes exclusively to sister chromatids, suggesting conservative segregation. To show this, we used ectopic integration to characterize cells that carry either the MRE11 or mre11A470T alleles at the genomic g site, and a second opposing mre11A470T or MRE11 allele, respectively, at an ectopic site.
After revision:  Our data show that telosomes predominantly restrict both MRE11 and mre11A470T g site, and a second opposing mre11A470T or MRE11 allele, respectively, at an ectopic site.