Before revision: Events such as cancer might always be considered serious, whereas liver disease, depending on its CTCAE ( Common Terminology Criteria for Adverse Events ) grade—Grades 1 or 2 are generally considered non-serious and Grades 3-5 may be considered serious.
After revision: Events such as cancer might always be considered serious, whereas liver disease, depending on its (CTCAE Common Terminology Criteria for Adverse Events ) grade—Grades 1 or 2 are generally considered non-serious and Grades 3-5 may be considered serious.