Before revision: tumoroids, organoids, cell clusters, single cells) and subsequent exposition to the clinically most important cytotoxic agents (5-FU, oxaliplatin, irinotecan, individually or in combinations (CAPOX, FOLFOX, FOLFIRI, FOLFOXIRI), as well as to other cytotoxic substances,
After revision: Tumor cells can be grown in different environments including 3-dimensional organoids, on chips that simulate the tumor microenvironment, or xenografted on to animal models.tumoroids, organoids, cell clusters, single cells) and subsequent exposition to the clinically most important cytotoxic agents (5-FU, oxaliplatin, irinotecan, individually or in combinations (CAPOX, FOLFOX, FOLFIRI, FOLFOXIRI), as well as to other cytotoxic substances,