Before revision:  In the present study structure of 3CL^{pro is used to study drug: 3CL^{pro interactions and thus to investigate whether all or any of the main chemical constituents of Tinospora cordifolia (e.g., berberine (C_{20 , \beta-sitosterol (C_{29 \rm{(C_{21}H_{25}NO_{4})} \rm{(C_{28}H_{58}O))} can be used as an anti-viral drug against SARS-CoV-2.
After revision:  In the present study structure of 3CL^{pro is used to study drug: 3CL^{pro interactions and thus to investigate whether all or any of the main chemical constituents of Tinospora cordifolia (e.g., berberine (C_{20 , \beta-sitosterol (C_{29 , tetrahydropalmatine\rm{(C_{21}H_{25}NO_{4})} \rm{(C_{28}H_{58}O))} can be used as an anti-viral drug against SARS-CoV-2.