Before revision:  We use simulations to provide evidence for our hypotheses, taking into account data showing that certain B cell mutations are more likely than others  .
After revision:  We use simulations to provide evidence for our hypotheses, taking into account data showing that certain B cell mutations are more likely than others . Our findings are consistent with memory B cells having high-affinity to mutated antigens, but do not provide strong evidence that memory B cells will be more useful than selected naive B cells for seeding the secondary germinal centers .