Before revision: In this article , we present a polymer model of the chromosome that can be parameterized to quantitatively reproduce contact probabilities measured in high-throughput chromosome conformation capture  (Hi-C) or genome architecture mapping  (GAM) experiments.
After revision: It is widely believed that the folding of the chromosome in the nucleus has a major effect on genetic expression. For example co-regulated genes in several species have been shown to colocalize in space despite being far away on the DNA sequence. In this manuscript , we present a polymer model of the chromosome that can be parameterized to quantitatively reproduce contact probabilities measured in high-throughput chromosome conformation capture (Hi-C) or genome architecture mapping (GAM) experiments.