Before revision:  More importantly , the model allows to pinpoint few deviations in human from the neutral scenario it assumes: three over-expanded families corresponding to HOX and FOX type genes , a set of "singleton" TFs for which duplication seems to be selected against, and an higher-than-average rate of diversification of the binding preferences of TFs with a Zinc Finger DNA binding domain.
After revision:  More importantly , the model allows to pinpoint few deviations from the neutral scenario it assumes: three over-expanded families corresponding to HOX and FOX type genes , a set of "singleton" TFs for which duplication seems to be selected against, and an higher-than-average rate of diversification of the binding preferences of TFs with a Zinc Finger DNA binding domain.