Before revision:  TF3P can encode the 3D force fields information of molecules and demonstrates its stronger ability to capture 3D structural changes,  recognize molecules alike in 3D but not in 2D, and recognize similar targets inaccessible by other fingerprints, including the solely existing 3D fingerprint E3FP, based on only ligands similarity.
After revision:  TF3P can encode the 3D force fields information of molecules and demonstrates its stronger ability to capture 3D structural changes, recognize molecules alike in 3D but not in 2D, and recognize similar targets inaccessible by other 2D or 3D fingerprint E3FP, based on only ligands similarity.