Before revision:  It turns out that our model successfully reproduces the patch-clamp experimental data of the steady-state open probability, the mean close duration, and the bi-exponential distribution of the open duration . Particularly, our model successfully describes the  bimodal [Ca^{2+}]
After revision:  It turns out that our model successfully reproduces the patch-clamp experimental data of the steady-state open probability, the mean close duration, and the bi-exponential distribution of the open duration . Particularly, our model successfully describes the complicated bimodal [Ca^{2+}]