Before revision: A nine state master equation for Na+ channel gating that describes the coupling between three activation sensors, a two-stage fast inactivation process and a slow inactivated state, may be reduced to a system of kinetic equations for a six state system.
After revision: A thirteen-state master equation for Na+ channel gating that describes the coupling between three activation sensors, a two-stage fast inactivation process and a slow inactivated state, may be reduced to a system of kinetic equations for a six state system.