Before revision:  To address the need for quantitative VBA validation we propose a  framework consisting of morphological phantoms, and four quantitative metrics. We address several factors that impact VBA results, including registration parameters, and template construction strategies.
After revision:  To address the need for quantitative VBA validation we propose a framework consisting of morphological phantoms, and four metrics. This addresses several sources that impact VBA results, including registration parameters, and template construction strategies.