Before revision:  In particular, we find that the Shannon information communicated by an allosterically regulated protein is a complex function of the transition kinetics between its different allosterically regulated states  and their respective product formation rates . Surprisingly, our work implies that allosteric down-regulation of protein product formation may not only be used to silence proteins as one would normally expect.
After revision:  In particular, we find that the Shannon information communicated by an allosterically regulated enzyme and a receiver protein downstream in the signaling pathway depends on the transition kinetics between its different allosterically regulated states and their respective product formation rates . Surprisingly, our work implies that allosteric down-regulation of protein product formation may not only be used to silence proteins as one would normally expect.