Before revision: The mesoscopic Peyrard-Bishop DNA Hamiltonian describes the main molecular interactions with simple potentials , resulting in an efficient calculation of the melting of the duplex helix. It is based on a 2D model which can be simplified to calculate the classical partition function with the transfer-integral technique.
After revision: The mesoscopic Peyrard-Bishop DNA Hamiltonian describes the main molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a 2D model which can be simplified to calculate the classical partition function with the transfer-integral technique.