Before revision:  Instead, as evaluated by bootstrapping, the information content of SHAPE data appears insufficient to define these RNAs' structures.
After revision:  Instead, as evaluated by bootstrapping, the information content of SHAPE data appears insufficient to define these RNAs' SHAPE data, as evaluated by a nonparametric bootstrapping analysis. Beyond these benchmark cases, bootstrapping suggests a low level of confidence (<50\%) in the majority of helices in a previously proposed SHAPE-directed model for the HIV-1 RNA genome.