Before revision:  In this paper, we trace the history of how the 3D CNN was developed from its machine learning roots, give a brief mathematical description of 3D CNN and  the preprocessing steps required for medical images before feeding them to 3D CNNs.
After revision:  In this paper, we trace the history of how the 3D CNN was developed from its machine learning roots, we provide a brief mathematical description of 3D CNN and the preprocessing steps required for medical images before feeding them to 3D CNNs.