Before revision:  The goal of this review is to synthesize studies published mostly in the last 25 years on the membrane trafficking of the five major junction transmembrane proteins: claudins, occludin, and junction adhesion molecules (JAMs) in tight junctions;
After revision:  The goal of this review is to synthesize published studies on the membrane trafficking of the five major junction transmembrane proteins: claudins, occludin, and junction adhesion molecules (JAMs) in tight junctions;