Before revision: Clinical significance Diseases There are many CNS diseases and conditions, including infections such as encephalitis and poliomyelitis , early-onset neurological disorders including ADHD and autism , seizure disorders such as epilepsy , headache disorders such as migraine , late-onset neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and essential tremor , autoimmune and inflammatory diseases such as multiple sclerosis and acute disseminated encephalomyelitis , genetic disorders such as Krabbe's disease and Huntington's disease , as well as amyotrophic lateral sclerosis and adrenoleukodystrophy.
After revision: Clinical significance Diseases There are many CNS diseases and conditions, including : Infections such as encephalitis and poliomyelitis Early-onset neurological disorders including ADHD and autism Seizure disorders such as epilepsy Headache disorders such as migraine Late-onset neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and essential tremor , autoimmune and inflammatory diseases such as multiple sclerosis and acute disseminated encephalomyelitis Genetic disorders such as Krabbe's disease and Huntington's disease  as well as amyotrophic lateral sclerosis and adrenoleukodystrophy.