Before revision:  In this study, we develop an in vitrovascularized tumor platform that allows for investigation of tumor-stromal interactions in three breast tumor derived cell lines of varying aggressiveness: MDA-IBC3, SUM149, and  MDA-MB-231 .
After revision:  In this study, we develop an in vitrovascularized tumor platform that allows for investigation of tumor-stromal interactions in three breast tumor derived cell lines of varying aggressiveness: MDA-IBC3, SUM149, and tumor-ECM interactions specific to IBC. Platforms consisting of collagen type 1 ECM with an endothelialized blood vessel were cultured with IBC cells, MDA-IBC3 (HER2+) or SUM149 (triple negative), and for comparison to non-IBC cells, MDA-MB-231 .