Before revision:  We compare our procedure with state-of-the-art methodologies in simulations and applications . We use our method to re-examine the scientific question of how Beringian bison went extinct analyzing modern and ancient molecular sequences of bison in North America, and to reconstruct population size trajectory of SARS-CoV-2 from viral sequences collected in France and Germany .
After revision:  We compare our procedure with state-of-the-art methodologies in simulations and applications .