Before revision: Developing efficient computational methods to change the state of a cell from an undesirable condition, e.g. diseased, into a desirable, e.g. healthy, condition is an important goal of systems biology.
After revision: Developing efficient computational methods to change the state of a cell from an undesirable condition, e.g. diseased, into a desirable, e.g. healthy, condition is an important problem in systems biology.