Before revision:  We develop a  theoretical framework for addressing this question that is based on: (1) considering a computational model for the flow of ribosomes along the mRNA, called the ribosome flow model, but with rates that are random variables ; and (2) analyzing the model steady-state behaviour using tools from random matrix theory .
After revision:  We develop a theoretical framework for addressing this question by modeling the rates as identically and independently distributed random variables and using tools from random matrix theory .