Before revision:  These results indicate that iMD-VR affords sufficient control for users to generate reversible binding pathways that recover crystallographic poses, offering a new approach for simulating drug docking and generating binding hypothesis .
After revision:  These results indicate that iMD-VR affords sufficient control for users to carry out the detailed atomic manipulations required to dock flexible ligands into dynamic enzyme active sites and recover crystallographic poses, offering a new approach for simulating drug docking and generating binding hypothesis .