Before revision:  In light of the COVID-19 pandemic, we focus on characterizing the global features of SARS-Cov2 (COVID-19) spike glycoprotein. Our objective is to review and apply our network approaches to gain insights into a key viral protein at the structural level. We employ dynamical side-chain network concepts on COVID-19 spike glycoprotein, which is crucial for viral entry into human cells.
After revision:  We present technical details of the construction and analyses of protein structure networks, encompassing both the non-covalent connectivity and dynamics. We examine the selection of optimal criteria for connectivity based on the physical concept of percolation. We highlight the advantages of using side-chain network concepts on COVID-19 spike glycoprotein, which is crucial for viral entry into human cells.