Before revision:  If the intracellular chemical reactions include multibody reactions , in particular, catalytic reactions, this advantageous leakage of essential metabolites is shown to be possible and indeed typical for most of metabolic networks via a mechanism termed as " catalytic flux control.
After revision:  If the intracellular chemical reactions include multibody reactions , in particular, catalytic reactions, this advantageous leakage of essential metabolites is shown to be possible and indeed typical for most of metabolic networks via a mechanism termed as " flux control