Before revision:  Inspired by biological processes such as protein synthesis  and motor protein transport, we intro- duce the concept of localized dynamical sites coupled to a driven lattice gas dynamics.
After revision: Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically non-static: affected by a fluctuating environment, they can undergo conformational changes. This is particularly true in biological cells, where the state of the substrate is often coupled to the active motion of macromolecular complexes, such as motor proteins on microtubules or ribosomes on mRNAs, causing new interesting phenomena. Inspired by biological processes such as protein synthesis and motor protein transport, we intro- duce the concept of localized dynamical sites coupled to a driven lattice gas dynamics.