Before revision:  This paper introduces a dynamic metabolic modelling framework that is a synthesis of recent ideas on resource allocation and the powerful optimal control formulation of Ramkrishna and colleagues.
After revision: Organisms have evolved a variety of mechanisms to cope with the unpredictability of environmental conditions, and yet mainstream models of metabolic regulation are typically based on strict optimality principles that do not account for uncertainty. This paper introduces a dynamic metabolic modelling framework that is a synthesis of recent ideas on resource allocation and the powerful optimal control formulation of Ramkrishna and colleagues.