Before revision: Exerkines come in many forms, including hormones, metabolites, proteins and nucleic acids; are synthesized and secreted from a broad variety of tissues and cell types; and exert their effects through endocrine, paracrine and/or autocrine pathways.
After revision: BackgroundExerkines come in many forms, including hormones, metabolites, proteins and nucleic acids; are synthesized and secreted from a broad variety of tissues and cell types; and exert their effects through endocrine, paracrine and/or autocrine pathways.