Before revision:  The results indicate that living cells realize optimal search strategies for various intracellular transport problems  economically through a spatial URLanization that involves  only a narrow actin cortex rather than a cell body filled with randomly oriented actin filaments.
After revision:  The results indicate that living cells realize optimal search strategies for various intracellular transport problems  economically through a spatial URLanization that involves radial microtubules in the central region and only a narrow actin cortex rather than a cell body filled with randomly oriented actin filaments.