Before revision:  As COVID-19 cases are re-surging in the U. S. and around the world, a Machine Learning pipeline like MLHOis crucial to improve our readiness for confronting the potential future waves of COVID-19, as well as other novel infectious diseases that may emerge in the near future .
After revision:  Our results demonstrated that while demographic variables (namely age) are important predictors of adverse outcomes after a COVID-19 cases are re-surging in the U. S. and around the world, a Machine Learning pipeline like MLHOis crucial to improve our readiness for confronting the potential future waves of COVID-19, as well as other novel infectious diseases that may emerge in the near future .