Before revision: thumb 3DISCO (stands for “3D imaging of solvent-cleared organs“) is histological method which make biological samples more transparent (so called “cleared”) , by using series of organic solvents for matching refractive index (RI) of tissue and surrounding medium.
After revision: thumb 3DISCO (stands for “3D imaging of solvent-cleared organs“) is a histological method that make biological samples more transparent (so called “cleared”) , by using series of organic solvents for matching refractive index (RI) of the tissues with that of thethe surrounding medium.