Before revision:  In this work we build an automatically trainable model that is based on a combination of thermodynamic parameters, chemical probing data ( Selective 2^\prime Hydroxyl Acylation analyzed via Primer Extension , SHAPE), and co-evolutionary data (Direct Coupling Analysis, DCA)
After revision:  Here, we build a set of models that combine thermodynamic parameters, chemical probing data ( Selective 2^\prime Hydroxyl Acylation analyzed via Primer Extension , SHAPE), and co-evolutionary data (Direct Coupling Analysis, DCA)