Before revision:  Further, neurons coordinating activity across distinct neuronal clusters are seen to appear early which relates the temporal hierarchy imposed by development to the functional role of neurons. By providing a framework for a mechanistic understanding of how developmentshapes a nervous system, our results complement interpretive analysis of how efficiency and optimality govern its design . Providing crucial insights for understanding principles that may be common across URLanisms, our study shows how the trajectory in the developmental landscape constrains the eventual spatial and network URLanization of a nervous system.
After revision:  Further, neurons coordinating activity across distinct neuronal clusters are seen to appear early which relates the temporal hierarchy of their appearance during the course of development . Providing crucial insights for understanding principles that may be common across URLanisms, our study shows how the trajectory in the developmental landscape constrains the eventual spatial and network URLanization of a nervous system.