Before revision: Generation of loops in dsDNA A single molecule study using atomic force microscopy (AFM) and tethered particle motion (TPM) has observed that ISWI can bound naked DNA in absence ATP wrapping DNA around the protein.
After revision: Generation of loops in dsDNA A single molecule study using atomic force microscopy (AFM) and tethered particle motion (TPM) has observed that ISWI can bind naked DNA in the absence of ATP, wrapping DNA around the protein.