Before revision:  The non-monotonic relation between abundances and Protein-Protein Interaction network degrees of yeast proteins validates our predictions. Furthermore, in agreement with our model we found that highly abundant yeast proteins show a positive correlation between their degree and dosage sensitivity with respect to overexpression .
After revision:  Based on these principles we generated and analyzed a possible realization of the proteome-wide PPI network in yeast. In this simulation we found that highly abundant yeast proteins show a positive correlation between their degree and dosage sensitivity with respect to overexpression .