Before revision:  In an attempt to throw light on this issue here we present analysis , in terms of the amide hydrogen exchange protection factor,  to determine the likely existence of structural fluctuations in the native-state consistent with both the protein's marginal stability upper bound and the metamorphism presence.
After revision:  In an attempt to throw light on this issue here we present analysis , in terms of the amide hydrogen exchange protection factor, to determine the likely existence of structural fluctuations in the native-state consistent with both the upper bound marginal stability of proteins and the metamorphism presence.