Before revision:  By analyzing the balance between mixing entropy and protein affinities, we elucidate by statistical mechanics arguments how such protein sorting in distinct domains can be explained without appealing to pre-existing lipidic micro-phase separations, as in the lipid raft scenario.
After revision:  By analyzing the balance between mixing entropy and protein affinities, we propose that such protein sorting in distinct domains can be explained without appealing to pre-existing lipidic micro-phase separations, as in the lipid raft scenario.