Before revision:  By comparing our results for a specific gene of the Escherichia coli bacteria with those for the corresponding homogeneous mRNA template, we demonstrate the effects of the sequence inhomogeneities of real genes on the fluctuations and noise . We also suggest {\it in-vitro} laboratory experimentsfor testing our theoretical predictions .
After revision:  By comparing our results for a specific gene of the Escherichia coli bacteria with those for the corresponding homogeneous mRNA template, we demonstrate the effects of the sequence inhomogeneities of real genes on the fluctuations and noise in translation. In principle, our new predictions can be tested by carrying out {\it in-vitro} laboratory experimentsfor testing our theoretical predictions .