Before revision:  Scientists measure rate constants associated with these reactions  in an optical biosensor: an instrument in which ligand molecules are convected through a flow cell, over a surface on which receptors are immobilized. In applications such as DNA damage repair multiple simultaneous reactions occur on the surface of the biosensor. We quantify transport effects on such multiple-component reactions, which result in a nonlinear set of integrodifferential equations for the reacting species concentrations.
After revision:  Scientists measure rate constants associated with these reactions in an optical biosensor: an instrument in which ligand molecules are convected through a flow cell, over a surface on which receptors are confined. Currently, scientists are using optical biosenors to measure the kinetic rate constants associated with DNA translesion synthesis--a process critical to DNA damage repair. Biosensor experiments to study this process involve multiple interacting components on the sensor surface. This multiple-component reactions, which result in a nonlinear set of integrodifferential equations for the reacting species concentrations.