Before revision:  We apply the method to simulate multivalent ligand-receptor interaction systems . Simulation results reveal insights into ligand-receptor binding kinetics that are not available from previously developed equilibrium models .
After revision:  We apply the method to simulate interactions of an m-valent ligand with an n-valent cell-surface receptor . Simulation results reveal insights into ligand-receptor binding kinetics that are not available from previously developed equilibrium models .