Before revision: If you know from experience that the signals can shift relative to each other by as much as 2 microseconds, for instance, designing your system with at least 2 microseconds of timing margin will prevent incorrect interpretation of the data signal by the receiver.
After revision: If it is known from experience that the signals can shift relative to each other by as much as 2 microseconds, for instance, designing the system with at least 2 microseconds of timing margin will prevent incorrect interpretation of the data signal by the receiver.