Before revision: The fundamental law for protein folding is the  Thermodynamic Principle : the amino acid sequence of a protein determines its native structure and the native structure has the minimum Gibbs free energy among all possible conformations of the protein. The very essential of the thermodynamic principle, a Gibbs free energy formula G(   ) for every possible conformation   of the protein , has never been theoretically formulated from the fundamental physical laws.
After revision: The fundamental law for protein folding is the  Thermodynamic Principle : the amino acid sequence of a protein determines its native structure and the native structure has the minimum Gibbs free energy . If all chemical problems can be answered by quantum mechanics, there should be a quantum mechanics derivation of Gibbs free energy formula G(  ) for every possible conformation  of the protein , has never been theoretically formulated from the fundamental physical laws.