Before revision:  In this work we propose to use the eigenvector centrality metric distribution as a mean of post-processing molecular dynamics simulations to determine the principal correlation paths involved in the transfer of information which is essential for the normal performance of enzymatic activity.
After revision:  In this work we propose to use the eigenvector centrality metric in terms of the mutual information, as a mean of post-processing molecular dynamics simulations to determine the principal correlation paths involved in the transfer of information which is essential for the normal performance of enzymatic activity.