Before revision:  The translation produces a network with stochastically equivalent dynamics, but the DRE of the expanded network can be interpreted as a correction to the original ones. Through a publicly available software implementation of FSE , we demonstrate its effectiveness in models from systems biology which challenge state-of-the-art techniques due to the presence of intrinsic noise, multi-scale population dynamics , and multi-stability.
After revision:  The translation produces a network with stochastically equivalent dynamics, but the DRE of the expanded network can be interpreted as a correction to the original one. The effectiveness of FSE is demonstrated in models that challenge state-of-the-art techniques due to the presence of intrinsic noise, multi-scale population dynamics , and multi-stability.