Before revision:  We first show that DKT estimates plausible multimodal trajectories in PCAthat agree with previous literature. We further validate DKT in two situations: (1) on synthetic data , showing that it can accurately estimate the ground truth parameters and (2) on 20 DTI scans from controls and PCA patients, showing that it has favourable predictive performance compared to standard approaches .
After revision:  Although validation is challenging due to lack of data in PCA, we validate DKT on synthetic data , showing that it can accurately estimate the ground truth parameters and (2) on 20 DTI scans from controls and PCA patients, showing that it has favourable predictive performance compared to standard approaches .