Before revision:  We expect our particle picking tool, Topaz , based on CNNs trained with GE-binomial, to be an essential component of single particle cryoEM analysisand our GE-binomial objective function to be widely applicable to positive-unlabeled classification problems .
After revision:  We expect our particle picking tool, Topaz , based on CNNs trained with GE-binomial, to be an essential component of cryoEM analysis .