Before revision: Neurodegeneration and cancer may share a common pathomechanism of defective cell-cycle control as a consequence of age-dependent accumulation of DNA damage. The response to DNA damage is controlled by the tumor suppressor P53 that coordinates a complex network of cellular pathways.
After revision: Cells are constantly exposed to DNA damaging insults. To protect URLanism, cells developed a complex molecular response coordinated by P53 that coordinates a complex network of cellular pathways.