Before revision:  We show that the core of the cellular autocatalytic network is the transcription--translation machinery -- in itself an autocatalytic network comprising several coupled autocatalytic cycles, including the ribosome, RNA polymerase, and tRNA charging cycles.
After revision:  We show that the core of the cellular autocatalytic network is the transcription -- translation machinery -- in itself an autocatalytic network comprising several coupled autocatalytic cycles, including the ribosome, RNA polymerase, and tRNA charging cycles.