Before revision:  Based on the correlation structure of the four individually varying, and readily interpretable model parameters and eleven popular non-compartmental parameters , recommendations for statistical analysis plans are derived .
After revision:  Based on the correlation structure of the four individually varying, and readily interpretable model parameters and eleven popular non-compartmental parameters . Based on these analyses, we recommend to use the minimum-maximum cortisol difference and the minimum concentration as proxy measures of reactivity and recovery, respectively .