Before revision:  Our study goes all the way from resource-light, multiscale computational predictions of crucial hotspot inter-atomic interactions to experimental validation by biophysical assays of the effect of site-directed mutagenesis  on capsid assembly.
After revision:  Our study goes all the way from resource-light, multiscale computational predictions of crucial hotspot inter-atomic interactions to experimental validation by biophysical assays of the effect of site-directed mutagenesis ' effect on capsid assembly.