Before revision: Since the estimate provides little support for causal role mutation accumulation in human aging , damaging mutations, germline and somatic, can only contribute to aging as a result of higher-order effects including interactions of multiple forms of damage.
After revision: Since the estimate provides little support for causal role mutation accumulation in human ageing , damageing mutations, germline and somatic, can only contribute to aging as a result of higher-order effects including interactions of multiple forms of damage.