Before revision:  The states result from large fluctuations of a duplex and have a great influence on a wide range of biochemical processes , including electric charge transfer in DNA  . A comparative analysis of kinetic and thermodynamic experimental data on  DNA open states has been performed for a wide temperature range .
After revision:  The states result from large fluctuations of a duplex and have a great impact on a number of biochemical processes , including electric charge transfer in DNA . A comparative analysis of kinetic and thermodynamic experimental data on DNA open states has been performed for a wide temperature range .