Before revision:  Our proposed cell-based mechanostat theory gives a cellular interpretation of the different phenomena and timescales occurring during the mechanical adaptation of bone tissues . The consideration of osteocyte desensitisation and osteocyte replacement enables to resolve several shortcomings of the standard mechanostat theory.
After revision:  Our proposed cell-based mechanostat theory gives a cellular interpretation of the different phenomena and timescales occurring during the mechanical adaptation of bone tissues , lending support to this theory.