Before revision:  As an input-output approach, I-V curve shaping proves effective in enabling robust and accurate control of the circuit behavior , suggesting a close analogy to the biophysical mechanisms of neuromodulation  .
After revision:  As an input-output approach, I-V curve shaping proves effective in enabling robust and accurate control of the circuit behavior , suggesting a close analogy to the biophysical mechanisms of neuromodulation . As a proof of concept, we simulate a SPICE model composed of MOSFET transconductance amplifiers operating in the weak inversion regime .