Before revision:  Do living cells operate at the thermodynamic limits for taking a measurement? Here, we consider a canonical biochemical network for receptor readout and show how it maps onto a measurement protocol of the type studied in the computational literature.
After revision:  Can cells reach the thermodynamic limit of minimal dissipation for a given measurement accuracy, and, if not, what is the cause? We consider a canonical biochemical network for receptor readout and show how it maps onto a measurement protocol of the type studied in the computational literature.