Before revision:  rather we present an artificial neural network inspired by those biological systems in the human brain, that has unique strengths .
After revision:  rather we present an artificial neural network inspired by those biological systems in the human brain, that has unique strengths. We demonstrate that we can tag an image with salience with only a single training iteration, and that the same image will then produces the highest reverse salience signal during classification. We explore the effects of salience on learning via its effect on the activation functions of each node, as well as on the strength of weights in the network. We demonstrate that a salience signal improves classification accuracy of the specific image that was tagged with salience, as well as all images in the same class, while penalizing images in other classes. Results are validated using 5-fold validation testing on MNIST and Fashion MNIST datasets. This research serves as a proof of concept, and could be the first step towards introducing salience tagging into Deep Learning Networks and robotics .