Before revision: Network biology approaches have over the last decade proven to be very useful for the integration and generation of functional hypothesis by providing a context for specific molecular components and processes. Recent experimental and computational techniques yield networksof increased size and sophistication. The study of these complex cellular networks is emerging as a new challenge in biology. A number of dimensionality reduction techniques for graphs have been developed to cope with complexity of networks .
After revision: To cope with the complexity of large networks, a number of dimensionality reduction techniques for graphs have been developed to cope with complexity of networks .