Before revision:  This approach is particularly useful when  data noise can be represented as a probabilistic distribution: from the point of view of nonparametric regression, the wQISA estimator is robust to random data perturbation such as noise and outliers.
After revision:  This approach is particularly useful when the data noise can be represented as a probabilistic distribution: from the point of view of nonparametric regression, the wQISA estimator is robust to random data perturbation such as noise and outliers.