Before revision:  Based on the patch-clamp experimental data obtained from the outer membranes of isolated nuclei of theXenopus oocyte, we construct an allosteric competition model of single IPR channels on their native ER membrane environment.
After revision:  Based on the patch-clamp experimental data obtained from the outer membranes of isolated nuclei of the oocyte, we construct an allosteric competition model of single IPR channels on their native ER membrane environment.