Before revision: Payloads include the microtubulin inhibitors monomethyl auristatin A MMAE , monomethyl auristatin F MMAF and mertansine, DNA binder calicheamicin and topoisomerase 1 inhibitors SN-38 and exatecan resulting in a renaissance for natural product total synthesis.
After revision: Payloads include the microtubulin inhibitors monomethyl auristatin E (MMAE) , monomethyl auristatin F (MMAF) and mertansine, DNA binder calicheamicin and topoisomerase 1 inhibitors SN-38 and exatecan resulting in a renaissance for natural product total synthesis.