Before revision:  We introduce novel nonparametric estimators for sharp and fuzzy designs based on the isotonic regression . The large sample distributions of introduced estimatorsare driven by scaled Brownian motions originating from zero and moving in opposite directions. Since these distributions are not pivotal, we also introduce a novel trimmed wild bootstrap procedure, which does not require additional nonparametric smoothing , typically needed in such settings, and show its consistency.
After revision:  We introduce novel nonparametric estimators for sharp and fuzzy designs based on the isotonic regression is inconsistent in this setting and derive the asymptotic distributions of boundary corrected estimators. Interestingly, the boundary corrected estimators can be bootstrapped without subsampling or additional nonparametric smoothing , typically needed in such settings, and show its consistency.