Before revision:  Steps a and b allow a global binding score of the ligand-receptor complexes , based on the distribution of the "effective affinity", i.e. the sum of the conformational and the docking energies . Step c. employes a complex network approach (Proteotronics) to characterize the electrical properties of the aptamers and the complexes.
After revision:  Steps a . and b. allow a global binding score of the ligand-receptor complexes , based on the distribution of the "effective affinity", i.e. the sum of the conformational and the docking energies . Step c. employes a complex network approach (Proteotronics) to characterize the electrical properties of the aptamers and the complexes.