Before revision:  We present a  framework for the construction and analysis of metabolic reaction networksthat can be tailored to reflect different environmental conditions . Using context-dependent flux distributions from Flux Balance Analysis (FBA), we produce directed networks with weighted links representing the amount of metabolite flowing from a source reaction to a target reaction per unit time.
After revision:  We present a systematic flux-based framework for the construction and analysis of metabolic reaction networksthat can be tailored to reflect different environmental conditions . Using context-dependent flux distributions from Flux Balance Analysis (FBA), we produce directed networks with weighted links representing the amount of metabolite flowing from a source reaction to a target reaction per unit time.