Before revision: Markov state models (MSMs) are a powerful means of understanding the structure and function of biomolecules by describing their free energy landscapes as a set of local minima (a.k.a. states) and the probabilities of transitioning between them.
After revision: Markov state models (MSMs) ---or discrete-time master equation models---are a powerful way of understanding the structure and function of biomolecules by describing their free energy landscapes as a set of local minima (a.k.a. states) and the probabilities of transitioning between them.