Before revision:  Additionally, our R package incorporates a novel method for calculating a consensus network (CN) from two or more networks . To visualize the resulting networks, the R packagecontains a visualization tool which allows for the direct network manipulation and access of node and link information. When testing the package on a standard laptop computer, we can conduct all calculations for systems of 20,000 genes in under two hours. Conclusion: In this work, we developed an R package that allows the computation of wTO networks, CNs and a visualization tool in the R statistical environment.
After revision:  Additionally, our R package incorporates a novel method for calculating a consensus network (CN) from two or more networks into our R package. We compare our new wTO package to state of art packages and demonstrate the application of the wTO and CN functions using 3 independently derived datasets from healthy human pre-frontal cortex samples. To showcase an example for the time series application we utilized a metagenomics data set. In this work, we developed an R package that allows the computation of wTO networks, CNs and a visualization tool in the R statistical environment.