Before revision:  This algorithm provides an alternate viewpoint on frequency-domain analysis and enables one to quantify the synchronizing timings among signaling pathways for rhythmical calcium oscillations . Numerical results show three types of calcium oscillations of SMCs in mesenteric arterioles: the spontaneous calcium oscillation, the agonist-dependent calcium oscillation, and the agonist-dependent calcium spike.
After revision:  This algorithm provides an alternate viewpoint on frequency-domain analysis and enables one to quantify the synchronizing timings among signaling pathways for rhythmical calcium oscillations . Numerical results show three types of calcium oscillations of SMCs in mesenteric arterioles: spontaneous calcium oscillation, the agonist-dependent calcium oscillation, and the agonist-dependent calcium spike.