Before revision:  As a consequence, the precise hierarchical modularity of healthy brains  is crumbled in schizophrenic ones, making possible a peculiar arrangement of region-to-region interaction that, in turns, produces several topologically equivalent backbones of the whole functional brain network. We hypothesize that the manifold nature of the basal scheme of URLanization within the brain, together with its altered hierarchical modularity, contributes to positive symptoms of schizophrenia. Our work also fits the disconnection hypothesis that describes schizophrenia as a brain disorder, characterized by abnormal functional integration among brain regions .
After revision:  As a consequence, the precise hierarchical modularity of healthy brains is crumbled in schizophrenic ones, making possible a peculiar arrangement of the functional connections, characterized by several topologically equivalent backbones .