Before revision:  Further, we refined the targets for SBC-specificity by filtering out the genes involved in primary bone cancer , any other type of cancer or any other known disease.
After revision:  Further, we refined the targets for SBC-specificity by filtering out the genes from published literature which serves as a basis of ontological correlates of secondary bone cancer. Building on these results, we implement a strategy based on generic cancer genes , any other type of cancer or any other known disease.