Before revision: History Questions about the optimal stopping policies in the context of clinical trials have been open from the 1940s and in the 1960s a few authors analyzed simple models leading to optimal index policies, but it was only in the 1970s that Gittins and his collaborators demonstrated in a markovian framework that the optimal solution of the general case is an index policy whose "dynamic allocation index" is computable in principle for every state of each project as a function of the single project's dynamics.
After revision: History Questions about the optimal stopping policies in the context of clinical trials have been open from the 1940s and in the 1960s a few authors analyzed simple models leading to optimal index policies, but it was only in the 1970s that Gittins and his collaborators demonstrated in a Markovian framework that the optimal solution of the general case is an index policy whose "dynamic allocation index" is computable in principle for every state of each project as a function of the single project's dynamics.