Before revision:  Counter-intuitively, patterns in those interactions effectively revealed by FunChisq enlist a network inference principle of applying perturbations to a biological system such that it transits between linear and nonlinear working zones, instead of operates only at a linear working zone.
After revision:  Counter-intuitively, patterns in those interactions effectively revealed by FunChisq enlist an experimental design principle essential to network inference -- perturbations to a biological system such that it transits between linear and nonlinear working zones, instead of operates only at a linear working zone.