Before revision: This evidence in considered to be of the "moderate" level of certainty by a 2023 Cochrane Systematic Review, however, the safety profile was not clear in these studies as adverse effects were not well considered or properly reported.
After revision: This evidence is considered to be of the "moderate" level of certainty by a 2023 Cochrane Systematic Review, however, the safety profile was not clear in these studies as adverse effects were not well considered or properly reported.