Before revision:  The features inferred by the RBM can be biologically interpreted in terms of structural modes, including residue-residue tertiary contacts and extended secondary motifs (\alpha-helix and \beta-sheet) , of functional modes controlling activity and ligand specificity , or of phylogenetic identity.
After revision:  The features inferred by the RBM can be biologically interpreted in terms of structural modes, including residue-residue tertiary contacts and extended secondary motifs (\alpha-helix and \beta-sheet) and intrinsically disordered regions), to function (such as activity and ligand specificity , or of phylogenetic identity.