Before revision: Moderate evidence summarized in clinical guidelines as of 2022 suggests that the daily intake of 400–600 mg /d of flavan-3-ol could have a small but statistically significant benefit to cardiometabolic health .
After revision: As of 2022 , food-based evidence indicates that intake of 400–600 mg per day of flavan-3-ols could have a small positive effect on cardiovascular biomarkers .