Before revision:  Test results prove that it is effective to quantity time irreversibility by measuring probabilistic divergence of symmetrical ordinal patternsand validate our hypothesis that epilepsy has lasting impacts on brain' nonlinear dynamics, leading to a decline in brain signals directional asymmetry or time irreversibility, and the losing temporal asymmetries stemming from our findings may contribute to the preclinical diagnosis of epilepsy .
After revision:  Test results prove that it is promising to quantify time irreversibility by measuring probabilistic divergence of symmetrical ordinal patternsand validate our hypothesis that epilepsy has lasting impacts on brain' nonlinear dynamics, leading to a decline in brain signals directional asymmetry or time irreversibility, and the losing temporal asymmetries stemming from our findings may contribute to the preclinical diagnosis of epilepsy .