(A) Relative transcripts of components of Notch signaling, Wnt signaling, Hedgehog signaling pathway in IMA tumors of KLN group relative to KL mice (n=4 per group). Results are mean ± SD. Significance was calculated by two-tailed unpaired Student's t-test with Welch's correction. **p=0.0048 (Hes1), ***p=0.0003 (Hes5), **p=0.0051 (Hey1), **p=0.0025 (Hey2), *p=0.0110 (Ccnd1). 