Figure 3. 3D replication profile.(A) Comparison of replication profiles of the synchronized populations used for the analysis displayed in Fig 2G. The read coverage of raw Hi-C libraries reflects the replication progression throughout S phase, plotted along the 16 chromosomes of the yeast genome (top axis; blue curve). The replication timing obtained in this study is highly similar to the one from McCune et al., 2008 (yellow curve). 