VcdRP is a dual-function regulator that represses CTX production in V. cholerae. Additionally, CRP and cAMP act on the regulator at the transcriptional level and suppress the production of VcdRP. The sRNA element (VcdR) acts via a conserved stretch of four consecutive cytosines to base pair with the translation initiation sites of PTS-specific and non-specific sugars, resulting in the inhibition of carbon uptake. The peptide VcdP binds to and increases the activity of citrate synthase enzyme, thereby modulating the levels of metabolites within the cycle. Thus, VcdR and VcdP together synchronize the carbon uptake and its subsequent utilization, thereby balancing carbon metabolism. 