Figure 6: Cognitive decline in 8-month old Fmn2 -/- mice is rescued by the HDAC inhibitor Vorinostat.. E. Left panel: The escape latency in the water maze test was significantly improved in the Fmn2-/- Vorinostat group when compared to the placebo group (P < 0.0001, F = 4,86; n=10/group). Right panel: Swim speed was not altered amongst groups 