(B) Tumor volumes measured daily in SCID/NOD mice treated with 3x106 irradiated YTS KIR2DL1 and NPs containing Cbl-b, c-Cbl and SHP-1 siRNA (n=13), or mice treated with 3x106 irradiated YTS KIR2DL1, and NPs containing N.S siRNA that served as a negative control (n=12). P values were calculated using two-tailed Student's t-test and are indicated by asterisks. * P < 0.05. Data are shown as mean ± SEM. 