D Representative DAPI staining (white) of P56 adult WT and 11B mouse neocortex illustrating the measurements of cortical perimeter (blue) and thickness (red). E, F Quantification of cortical perimeter (E) and thickness (F) in the rostral part of P56 adult WT and 11B mouse brain. G Data information: Images are single optical sections Scale bar, 1 mm Data are the mean of 8 (WT) and 8 (11B) adult littermate mice. Error bars indicate SD, two-tailed unpaired Student's t-test , * P < 0.05, ** P < 0.01, **** P < 0.0001. P = 0.0297 (E); P = 0.0092 (F) 