C: Combined violin and box plot (box shows lower quartile, median and upper quartile, whiskers extend to the most extreme data point within 1.5 the interquartile range of the box) of the proportion of low-complexity regions (D2P2) of GFP-TDP-25-specific, GFP-TDP-43-specific or shared/common interactors. TDP-25 specific (0.144 ± 0.021, n=432 Uniprot IDs) vs TDP-43 specific (0.266 ± 0.061, n=78) vs common interactors (0.184 ± 0.02, n=481): H(1)=22.276, df=2, p=1.455*10-5, η²[H]=0.0205, Kruskal-Wallis test. TDP-25 specific vs TDP-43 specific: ***p=0.00054, TDP-25 specific vs common: ***p=0.00035, TDP-43 specific vs common interactors: *p=0.04893, Pairwise Wilcoxon Rank Sum Tests with Benjamini-Hochberg correction. 