D. Schematic presentation of FET family of fusion oncoproteins, targeted DNA sequences and associated tumors. Left: FET N-terminal fusion partners and binding to SWI/SNF. Center: C-terminal transcription factor fusion partners and their DNA target sequences (JASPAR database). Right: Tumor types caused by respective fusion oncogene. Note tumor type specificity for each fusion oncoprotein and that the FET NTDs replace each other as fusion partners in some entities. Only a selection of the FET family fusion-oncoproteins and tumors is shown as more members are continuously discovered. 