E - Venn diagrams showing overlaps between groups of genes upregulated upon 15 min TPA treatment in RPB1-52R and RPB1-25R cells (left panel), 30 min TPA treatment in RPB1-52R and RPB1-25R cells (middle panel) as well as triple overlap between genes upregulated upon 15 min TPA in RPB1-52R and RPB1-25R cells with those upregulated upon 30 min TPA in RPB1-25R cells (right panel). Genes showing adjusted p value < 0.05 and log2 fold change >= 1 were considered upregulated. 