A. Using a representative Aft1 responsive gene, YHB1, fold-change differences between timepoints (solid grey dots) are compared to the LASSO regression model's fit (crosses). The model's predicted marginal contribution of three predicted regulators (Fet3, Hmx1, and Arn2) to the combinatorial control of YHB1 are shown with bars that sum to the model's overall fit (crosses). 