D) Statistical analysis of Ki67 CC3 (D) activity in ADC lung sections of vehicle (Veh) and phenformin (Phen) groups. The numbers of tumors analyzed over vehicle and phenfortmin groups were 32, 23 for CC3. Results were shown as mean ± SEM. Significance was calculated by two-tailed unpaired Student's t-test with Welch's correction. p=0.0162 (D). 