D, Quantification of the subcellular localization of the respective Fluc-EGFP protein in the presence of the indicated mHTT constructs. N=3 independent experiments. Three-way ANOVA with Tukey's multiple comparisons test. ANOVA: Localization, *p=0.019; HTT, n.s.; Fluc, n.s.; Localization x HTT, **p=0.0012; Localization x Fluc, ****p<0.0001; HTT x Fluc, n.s.; Localization x HTT x Fluc, ***p=0.0009. 