(F) Linear regression analysis for inter-architectural block-wise combinatorial mutations. The measured expressions (on the y-axis) for inter-architectural block-wise combinatorial mutations compared to the predicted expressions (on the x-axis) from the linear regression fit (log2 scale). Red solid line: y = x; red dashed lines: y = x ± 3×SD, where SD denotes the median of all standard deviations over all measured synthetic promoter constructs. Pearson coefficient 0.81.   