Figure 4: FMN2 is linked to age-associate memory declineD. Contextual freezing in 3-month old Fmn2 +/+ (n=14), APPPS1-21 (n=13), APPPS1-21_Fmn2 -/- (n=14) and Fmn2 -/- mice (n=14). Freezing behavior differed amongst groups (P = 0.0005, F= 6,947) and was significantly impaired in APPPS1-21_Fmn2 -/- mice when compared to the other groups (***P < 0,001).Error bars indicate SEM. 