D, E Venn diagrams showing overlaps between protein-protein interactions deduced from the CBL (D) or CBLB (E) CNs and those reported in the BioGRID database for Homo sapiens and Mus musculus. Two sets of analysis are shown according to Pearson correlation coefficient values (R<0.8 or R>0.8). Histograms below the Venn diagrams compare the probabilities to predict existing interactions with a random network (Random), the complete CN or the high confidence CN (R>0.8). 