(A) Fold change in cell number per colony in 18-hour period (n=3 pairs; each biological replicate is an average of 3 different colonies). (B, C) Live imaging reveals an increased frequency of type-II divisions in SSKO culture, as quantified in (B) (n=3 pairs; each biological replicate is an average of 3 different colonies); shown in (C) are representative images from a single experiment. (D) Cell cycle analysis of cultured Bu-HFSCs from control and Ovol2 SSKO cells (n=3 pairs) 