(B) H&amp;amp;E staining of representative atherosclerotic lesions in aortic root (upper panel-4x magnification) and brachiocephalic arteries (lower panel-10x magnification) at 14 week harvest. Lesion width of roots highlighted with black bars. (C) Quantification of root lesion size (left panel, *p=0.002), and of brachiocephalic lesion size (right panel, *p=0.001), both quantified as percent of total lumen area. Data in (C) are averaged lesion percentages from 4-6μm serial sections from each animal, n=9, 13, 15. All of the data represent the mean + SEM, *p<0.05 versus LNA-control tissue. Level of significance was determined using one-way ANOVA with Bonferroni's post test. 