(e) Binding of ICAM-1/CD54-Fc or VCAM-1/CD106-Fc to primary mouse neutrophils ('mAB 24' recognizing high-affinity conformation, 'Kim127' recognizing intermediate and high affinity conformation of β2 integrins) as assessed upon exposure to recombinant murine/human uPA-PAI-1, TNF, or saline by multi-channel flow cytometry, a representative histogram plot and quantitative data are shown (mean±SEM for n=4-7 mice/human blood samples per group; #p<0.05 vs. saline; One-way ANOVA). 