D-E Graph of log10(mean) versus log10(CV2) for endogenous gene targets that maintain CV2 (D) or decrease CV2 (E) after treatment with 20ng/mL TNF in Jurkat T cells (black), HeLa cells (red) or murine bone marrow derived macrophages (green). Gray shading indicates 95% CI of basal trendline. Poisson trendline indicated by dashed line. 