Figure 4: FMN2 is linked to age-associate memory declineF. During the probe test there was a significant difference amongst groups in the time spent in the target quadrant (P = 0.04, F = 3,22). Expect for APPPS1-21_Fmn2 -/- mice, all groups showed a significant preference for the target quadrant (*P < 0.05). A direct comparison between Fmn2 -/- and APPPS1-21_Fmn2 -/- mice revealed a significant reduction in the latter group (*P = 0,017). Error bars indicate SEM. 