F Left panel: Schematic diagram of dual luciferase reporter constructs. Right panel: Relative luciferase activity of WT or MUT (A-to-T mutation) TRAF4 3ʹUTR luciferase reporter in control, WT and MUT-ALKBH5 overexpressing cells. Firefly luciferase activity was measured and normalized to Renilla luciferase activity. 