B, C, Principal component (PC) analyses of normal (blue), tumor (orange) and residual (green) cells based on (B) RNA-sequencing data (normal, n=8; tumor and residual, n=4 each) and (C) lipidomics data (n=4). Data information: Number of replicates corresponds to individual mice used to derive organoids. Centroids represent the mean and concentration ellipses represent one standard deviation (level=0.68) of an estimated t-distribution based on the first two principal components. 