H GSEA plots showing gene sets that are differentially regulated between ILC and non-ILC FACS sorted intraductal PDXs, related to luminal progenitor features (left) and increased expression of basal and mesenchymal versus luminal genes (middle and right). Significance scores (P-values) of GSEAs are computed by nonparametric permutation tests, a procedure that yields only estimates of the P-values. 