E) Proportion of cell populations derived from Pacs1+/+;CD45.1 and Pacs1−/−;CD45.2 donors during competitive bone marrow reconstitution. Populations were determined based on the same markers as in (C) with the added congenic markers CD45.1 and CD45.2. Each symbol represents an individual recipient. Results are representative of two independent transplant experiments. Two-tailed unpaired t test, ns = not significant, *P < 0.05, **P < 0.01, and ***P < 0.001. 