(D) Correlation of the different types of data modalities of cancer cell lines profiled at multiple research sites. Spearman correlation was calculated between identical cell lines for the shared set of genes that were overlapping between any two datasets. Gray distributions show the correlation of non-identical cell lines between datasets from various research sites for comparison. Ng and Nc indicate the median [ranges] of the number of genes and cell lines, respectively, across the pairwise comparisons made between datasets from different research sites. More details on the breakdown of Nc and Ng by data modality and research site is available in Appendix Figure S5B and S6, respectively, and Appendix Figure S7C shows the correlation P-values adjusted for the sample size (Ng). For the point mutation view, only those genes having mutations with an associated functional consequence were considered in the Matthews correlation analysis. Only those datasets for which the mutation profiles were obtained using the whole-exome sequencing technology were considered in this study. Horizontal lines mark the median value. Target addiction score (TAS), Drug Sensitivity Score (DSS), Gene dependency (FUNC), protein phosphorylation (PHOS), protein expression (PEXP), gene expression (GEXP), copy number variation (CNV), point mutation (MUT) and methylation (METH) profiles. 