(c) Production of TNF was analyzed in mouse RAW 264.7 macrophages bEnd.3 microvascular endothelial cells as assessed in vitro by multi-channel flow cytometry upon exposure to recombinant murine uPA-PAI-1, TNF, or saline, quantitative data are shown (mean±SEM for n=4 experiments per group; #p<0.05 vs. saline; One-way ANOVA / t test). 