(B) Breast cancer specific survival (BCSS) based on gene expression and methylation levels of ECHDC1 in breast cancer patient tumors in the combined Metabric and Oslo datasets (n=3885). Patients in the low GEXP category class have lower BCSS than those in the non-low GEXP group. Numbers above the x-axis line indicate the number of patients in each group, defined by the color code, at each time point. P-value from age-adjusted Cox-proportion hazard model. 