C) Quantification of 2C1 stained area in livers from vehicle and 100mg/kg TID GSK716 treated animals at day 15 (top) and 21 (bottom), shown as total area and low-only or high and mid-only intensity stained areas. There were no significant differences between groups by Mann-Whitney U test; graphs show median±interquartile ranges, with n=5 per group.  