Figure 5: Memory decline in 8-month old Fmn2 -/- mice correlates with deregulated transcriptome plasticity I. Volcano plot showing genes differentially expressed in 3-month old APPPS1-21 mice compared to a wild type control group (green) and APPPS1-21_Fmn2 -/- mice compared to wild type control mice (purple). (FDR < 0,05, log2 fold change < +/- 0,5). The upper panel depicts the number of altered genes. 