(F) Venn diagram model depicting the co-expression of the nine TRs in cells lying within the early-iPSCs colonies on day 6 of reprogramming. The area of each circle represents the percentage of cells expressing each TR, as determined from the single single-cell experiments and the overlapping areas between circles represents the percentage of co-expression of two or three TRs, as revealed from our double and triple TR single-cell RNA expression experiments. The shaded blue area highlights the percentage of cells co-expressing all the nine TRs. 