raphical representation of the expected transcriptome changes with regard to Alu RNA expression and processing levels based on previous findings in mouse (Appendix Figure S1) and prior reports on the ability of Alu RNAs to control transcription (Mariner et al., 2008; Ponicsan et al., 2010; Yakovchuk et al., 2009) and become self-cleaved (Hernandez et al., 2020). 