(E) Fecal microbiota were analysed following administration of MBELNs (10 x 109 particle/100 µl/dose/day/mouse) for 7 days to C57BL/6 mice. Alpha diversity (Shannon index) was calculated at the family level and is displayed as a bar-and-whiskers plot for each individual combination of control and MBELN treatment. The centre line represents the median and the box encloses the 1st and 3rd quartiles ("hinges"). The upper and lower whiskers represent the furthermost points from the respective hinges, which are no more than 1.5 interquartile ranges from the hinge. The individual points are overlaid. Data are presented from five mice or biological replicates. 