The measurement of distances between the 5′- and 3′-ends of Target-L fragments on the same genomic strand. Heat map displays 5′-ends of Target-L in a window around the most abundant 1,000 3′-ends of Target-L. The measurement of distances between the 5′-ends and 3′-ends of Target-S fragments on the same genomic strand. The heat map displays 5′-ends of Target-S in a window around the most abundant 1,000 3′-ends of Target-S. The measurement of distances between the 5′-ends of Target-L and the 3′-ends of Target-S on the same genomic strand. The heat map displays 5′-ends of Target-L in a window around the most abundant 1,000 3′-ends of Target-S. The measurement of distances between the 5′-ends of Target-S and the 3′-ends of Target-L on the same genomic strand. The heat map displays 5′-ends of Target-S in a window around the most abundant 1,000 3′-ends of Target-L. 