Figure 1. Comparison of genome structures recovered from five synchronized stages over the cell cycle. (C, D) Comparison of contact maps. The 16 yeast chromosomes are displayed atop the maps. Black arrowheads: inter-telomere contacts. Yellow arrowheads: inter-centromeric contacts. Left panels: Hi-C maps obtained from two G1 cell populations synchronized independently (C) . Right panels: log-ratio between each pair of maps. Insets display magnifications of chr4. Blue to red color scales reflect the enrichment in contacts in one population with respect to the other (log2). 