Figure 6: Cognitive decline in 8-month old Fmn2 -/- mice is rescued by the HDAC inhibitor Vorinostat. D. Freezing behavior during the memory test was significantly increased in the Fmn2-/- Vorinostat group when compared to the placebo group (P = 0,04) (Fmn2-/- placebo, n=8; Fmn2-/- Vorinostat, n=9). 