E, Fluc-EGFP specific luciferase activity measured in the indicated brain regions of Fluc-EGFP mice at the indicated ages. Values are normalized to the 3-month-old group. N=5 Fluc-EGFP mice for each age group. One-way ANOVA with Bonferroni's multiple comparisons test. ANOVA: Hippocampus, *p = 0.0205; Cortex, **p = 0.0077; Cerebellum, n.s. Significant pairwise comparisons to the 3-month-old group are indicated on the graphs. 