(A-C) Computational docking of (A) PLY, (B) LLO and (C) SLO (in green) with the CTLD4 domain of MRC-1 (in red) was performed using the ClusPro 2.0 docking server. Modeling based on least energy configurations indicate that the unstructured loop of MRC-1 docks to the conserved cholesterol binding loop (in yellow) of PLY, LLO and SLO. The amino acid residues predicted to involve in hydrogen bonding interactions are zoomed in below. 