(A) The promoter region was divided into 7 building blocks: block 1 with 239 bp of a potential -1 nucleosomal sequence; block 2 with 73 bp sequence representing the ecdysone receptor binding region; block 3-6 with 131 bp sequence representing the native and perturbative core promoter regions from different architectures; block 7 with 240 bp of a potential +1 nucleosomal sequence. (B) Synthetic promoter design - building blocks. The promoter region (sketch in lower panel) was divided into 7 building blocks: block 1 with 239 bp sequence representing a potential -1 nucleosome; block 2 with 73 bp sequence representing the ecdysone receptor binding region; block 3-6 with 131 bp sequence representing the native and perturbative core promoter regions from different architectures; block 7 with 240 bp sequence representing a potential +1 nucleosome. ( 