B-G Quantification across the rostral-caudal axis (sections 1-9, B-D) and only the rostral part of the brain (sections 1-3, E-G) of cortical perimeter (B, E), cortical thickness (C, F) and ventricular length (D, G) of E18.5 WT (white) and 11B (black) mouse neocortex. Data information: Images are single optical sections Scale bar, 20 µm Data are the mean of 7 (WT) and 8-12 (11B) littermate embryos, which were derived from 4 separate litters. Error bars indicate SD. Two-way ANOVA, followed by Bonferroni's multiple comparisons test ; two-tailed unpaired Student's t-test , * P < 0.05, ** P < 0.01, **** P < 0.0001. WT vs. 11B, P < 0.0001; section number 3, P = 0.0322; section number 8, P = 0.0411 WT vs. 11B, P < 0.0001; section number 1, 2, P = 0.0233; section number 3, P < 0.0001 (C). P = 0.0476 (E); P < 0.0001 (F) 