EMBO/SourceData huggingface dataset:
Figure legend: "(E) Representative confocal images (63x) of cortical regions of 12-month mitoDendra -crossed WT and Miro1CKO mice stained with MAP2 and P-eIF2α. Arrows indicate the presence of megamitochondria (&gt;2.5 µm2), stars indicate neuronal somas without  megamitochondria."
NCBI gene IDs:
"Miro1: 59040"
Figure legend: "(F) Example zoom images of  neuronal somas with and without megamitochondria from cortical regions of 12-month  mitoDendra -crossed Miro1CKO mice stained with P-eIF2α. (G) Quantification P-eIF2α signal intensity (a.u.) from  neuronal somas with and without megamitochondria from cortical regions of 12-month mitoDendra-crossed Miro1CKO (n=16 sections from 4 mice; paired t-test)."
NCBI gene IDs:
"Miro1: 59040"
Figure legend: "(N) The hepatic mRNA levels of Il-6, Il-1β, Tnf-α and Mcp-1 involved in necroptosis at normal or necroptotic area from mice injected with PBS or rAAV in (H). n = 7 - 8 biological replicates."
NCBI gene IDs:
"Mcp-1: 20296
Il-1β: 16176
Il-6: 16193
Tnf-α: 21926"
Figure legend: "(L) The hepatic mRNA levels of Il-6, Il-1β, Tnf-α and Mcp-1 involved in necroptosis at normal or necroptotic area from mice in (E)."
NCBI gene IDs:
"Mcp-1: 20296
Il-1β: 16176
Il-6: 16193
Tnf-α: 21926"
Figure legend: "Body weight (D) of db/db mice after a single injection of rAAV-si-NC/Cyp4a14/Pebp1/Tat for 2 months. n = 10 - 12. rAAV-si-NC was packaged as indicated in Fig. 1A"
NCBI gene IDs:
"Cyp4a14: 13119
Pebp1: 23980
Tat: 234724"
Figure legend: "Two months after a single injection of rAAV-si-Pebp1, HFD-induced hyperglycemic and obese mice showed blood glucose levels (C) with the mice injected with rAAV-si-NC. n = 10 - 11. (D-E) Serum ALT (D) and AST (E) activities from mice in (B). The colored dots indicate the mice with high ALT or AST activity, and the same color dot in (D) and (E) indicates the same mouse."
NCBI gene IDs:
"Pebp1: 23980"
Figure legend: "(A) The effect of si-Pebp1 in primary mouse macrophages. n = 3. (B) Knockdown of Pebp1 markedly blocked the increase of some key inflammatory factors in mouse macrophages treated with poly(I:C). n = 6."
NCBI gene IDs:
"Pebp1: 23980"
Figure legend: "Knockdown of Pebp1 markedly blocked the loss of cell membrane integrity (C, n = 6 in duplicate or triplicate.) of mouse macrophages induced by poly(I:C) and z-VAD-fmk."
NCBI gene IDs:
"Pebp1: 23980"
Figure legend: "(E) Knockdown of Pebp1 attenuated the increase of p-Tbk1 level induced by poly(I:C). n = 3 biological replicates."
NCBI gene IDs:
"Pebp1: 23980"
Figure legend: "Knockdown of Tbk1 markedly blocked the loss of cell membrane integrity (H of mouse macrophages induced by poly(I:C) and z-VAD-fmk."
NCBI gene IDs:
"Tbk1: 56480"
Figure legend: "After a single injection of rAAV-si-Tbk1 for 11 weeks, the db/db mice showed blood glucose levels (M) with the mice injected with rAAV-si-NC. n = 11. (N-O) Serum ALT (N) and AST (O) activities of mice in (K)."
NCBI gene IDs:
"Tbk1: 56480"
Figure legend: "F RT-qPCR showing relative levels of miR-122 and indicated mRNAs in GA of indicated groups of mice. Data were normalized to U6 (for miR-122) or Ppib (for all mRNAs) and compared to control group receiving PBS (one-way ANOVA, n=4 or 5 mice per group). Data information: In bar graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ***P&lt;0.001, ns: not significant."
NCBI gene IDs:
"miR-122: 387231
Ppib: 19035
U6: 19864"
Figure legend: "C Responsiveness of the reporters to miR-122 mimic in transfected C2C12 (t-test, n=3 biological replicates). Data information: In bar graph, values are shown as mean ± SD. **P&lt;0.01, ns: not significant."
NCBI gene IDs:
"miR-122: RF00684"
Figure legend: "A Western blot showing levels of indicated proteins in C2C12 treated with indicated EVs, or transfected as indicated with miR-122 mimic or TP53 expression plasmid carrying silent mutation of the miR-122 binding site. Data information: Western blot signals are quantified and normalized to Gapdh."
NCBI gene IDs:
"miR-122: RF00684
TP53: 7157"
Figure legend: "D RT-qPCR indicated mRNAs (D) in GA of tumor-free and tumor-bearing mice. Data were normalized to Ppib (for all mRNAs) and compared to the tumor-free group (one-way ANOVA, n=4 or 5 mice per group). Data information: In bar graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ***P&lt;0.001, ns: not significant."
NCBI gene IDs:
"Ppib: 19035"
Figure legend: "C RT-qPCR showing indicated mRNAs in GA of indicated groups of mice. Data were normalized to Ppib and compared to control group receiving PBS (one-way ANOVA, n=4 mice per group). Data information: In bar graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ns: not significant."
NCBI gene IDs:
"Ppib: 19035"
Figure legend: "AAV8-TP53 virus or AAV8-eGFP control virus were injected into GA of both sides twice during the entire experiments, first immediately following implantation of MDA-MB-231 cells into the mammary fat pad, and then one month later. Muscles were collected at 6 weeks after tumor implantation. A Western blot showing indicated protein levels in the GA. Western blot signals are quantified and normalized to Gapdh."
NCBI gene IDs:
"eGFP: 
TP53: 7157"
Figure legend: "AAV8-TP53 virus or AAV8-eGFP control virus were injected into GA of both sides twice during the entire experiments, first immediately following implantation of MDA-MB-231 cells into the mammary fat pad, and then one month later. Muscles were collected at 6 weeks after tumor implantation. C Relative mtDNA/nDNA ratio in GA determined by PCR (two-tailed Student's t-test, n=8 mice per group). Data information: In all bar and line graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ***P&lt;0.001, ns: not significant."
NCBI gene IDs:
"eGFP: 
TP53: 7157"
Figure legend: "AAV8-TP53 virus or AAV8-eGFP control virus were injected into GA of both sides twice during the entire experiments, first immediately following implantation of MDA-MB-231 cells into the mammary fat pad, and then one month later. Muscles were collected at 6 weeks after tumor implantation. D Representative TEM images showing SS and IMF mitochondria and their quantification in GA (two-tailed Student's t-test, n=3 mice per group for the left subpanel and n=166 or 181 mitochondria analyzed per group for the right subpanel). Scale bar: 1 µm. Yellow bars: depths of SS mitochondrial areas; arrows: IMF mitochondrial area. Data information: In all bar and line graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ***P&lt;0.001, ns: not significant."
NCBI gene IDs:
"eGFP: 
TP53: 7157"
Figure legend: "AAV8-TP53 virus or AAV8-eGFP control virus were injected into GA of both sides twice during the entire experiments, first immediately following implantation of MDA-MB-231 cells into the mammary fat pad, and then one month later. Muscles were collected at 6 weeks after tumor implantation. E ROS levels in GA from indicated groups of mice. Quantified DHE signals were normalized to DAPI signals on the same section and used in analysis (two-tailed Student's t-test, n=4 mice per group). Scale bar: 50 µm. Data information: In all bar and line graphs, values are shown as mean ± SD. The boxes in the box-and-whiskers plots show the median (center line) and the quartile range (25-75%), and the whiskers extend from the quartile to the minimum and maximum values. *P&lt;0.05, **P&lt;0.01, ***P&lt;0.001, ns: not significant."
NCBI gene IDs:
"eGFP: 
TP53: 7157"
Figure legend: "a, Polychromasia (Wright-Giemsa stain, indicated by arrows) and increased reticulocytes (brilliant cresyl blue stain) revealed by staining blood smears from 6-week-old wild-type (WT) or Nix-/- mice (scale bar, 20 µm)."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "c, The relative luminescence units (RLU) of caspase activities in cultured RBCs and the suppression of annexin V staining in Nix-/- RBCs after 12-h culture in the presence of qVD-oph or solvent control (DMSO) (n = 3)."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "e, Mean fluorescent intensity (MFI) of ROS staining in RBCs after in vitro culture, and caspase activities in Nix-/- RBCs after 24 h culture with solvent control, ROS scavengers or qVD-oph (n = 3). BHT, butylated hydroxytoluene; CAT, catalase; TEM, tempol."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "f, Haematoxylin and eosin (HE) staining of spleen sections of 9-week-old wild-type and Nix-/- mice. Arrows denote iron deposits within macrophagecytoplasm. Iron deposits were also stained with Prussian blue, followed by counterstain with nuclear-fast red. Scale bar, 20 µm."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "g, Real-time RT-PCR of erythropoietin (Epo) (n = 12). For all relevant panels, statistical significance of the data (mean ± s.e.m.) is: *P &lt; 0.05; **P &lt; 0.01; ***P &lt; 0.001."
NCBI gene IDs:
"erythropoietin: 13856"
Figure legend: "c, CD71+Ter119+ reticulocytes sorted at day 3 after PHZ treatment were stained for LC3 and COX IV and analysed by deconvolution microscopy. Scale bar, 5 µm. The Pearson coefficiency for LC3 and COX IV co-localization at day 0 (mean ± s.e.m.) is: wild type, 0.81 ± 0.001; Nix-/-, 0.44 ± 0.036 (n = 35, P = 0.0006)."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "a, Ter119+CD71+ reticulocytes were sorted from the peripheral blood of wild-type and Nix-/- mice at day 6 after PHZ treatment. The cells were cultured for in vitro maturation in the presence of 10 µM FCCP or 1 µM ABT-737, followed by staining with Mitotracker deep red and phycoerythrin-conjugated anti-Ter119."
NCBI gene IDs:
"Nix: 12177"
Figure legend: "C Quantification of total numbers of generated cell types (BrdU+; rNSCs, IPCs  + neuroblasts, astrocytes) per area in the DGs  of 8 week-, 14 month-, and 21 month-old hGFAPeGFP animals. rNSCs: *** p = 0.00076, ** p = 0.0014; IPCs/neuroblasts  **** p &lt; 0.0001; astrocytes: *** p = 0.0008; * p = 0.0403; one-way ANOVA with Tukey's post hoc test. D Quantification of the percentages of generated cell types out of all generated cells (rNSCs, IPCs  + neuroblasts, astrocytes) in the DG  of 8 week-, 14 month-, and 21 month-old animals. rNSCs: not significant; IPCs/neuroblasts  **** p &lt; 0.0001, *** p = 0.0001; astrocytes: ** p &lt; 0.0019, **** p &lt; 0.0001; one-way ANOVA with Tukey's post hoc test. Data information: All data are represented as mean ± SEM; number of experimental animals (indicated by red dots): (C,D) n = 5 in 8 week-old mice, n = 6 in 14 month-old mice, n = 5 in 21 month-old mice"
NCBI gene IDs:
"eGFP: 
GFAP: 2670"
Figure legend: "G Confocal  images of 8 week- and 14 month-old NestinCreERT2; GFP  animals, which received tamoxifen  for five days (10 times, every 12 h) and were killed 12 days after the last tamoxifen  shot. The majority of recombined cells were rNSCs  [SOX2+ cell nuclei  (cyan) residing in the SGZ  with a NESTIN+ radial process (white)] and IPCs/neuroblasts [SOX2+ (cyan) nuclei located  to the SGZ, DCX+ cells (magenta) in the SGZ  and GZ, respectively], and only very few astrocytes  [SOX2+ cells (cyan) in the hilus, GZ, and ML] were generated by initially recombined rNSCs. H Quantification of total numbers of recombined (GFP+) rNSCs, IPCs/neuroblasts, astrocytes  per area in the DGs of 8 week- and 14 month-old animals. rNSCs: * p = 0.0460; IPCs/neuroblasts: **** &lt; 0.0001; astrocytes: not significant; unpaired t-test. Data information: All data are represented as mean ± SEM; number of experimental animals (indicated by red dots): ; (H) n = 3 in 8 week-old mice, n = 5 in 14 month-old mice  ; dotted lines border SGZ   and GZ; scale bars = 50 µm."
NCBI gene IDs:
"GFP: 
Cre: 2777477
ER: 2099
Nestin: 18008"
Figure legend: "RNAi injections schedule in starved conditions. Planarians are at 14dS when the amputation is performed (indicated by the grey cross at day 14). Live images show that cct3A(RNAi) planarians form a minimal blastema compared to controls at the time points shown. At the bottom are the number of planarians with the phenotype shown. The remaining planarians are dead by the time point of regeneration shown. dR indicates days of regeneration. RNAi injections schedule in feeding conditions. One extra feeding in respect to (B) is introduced one day prior to injections. Planarians are at 8dS when the amputation is performed. The live images show that most of the cct3A(RNAi) planarians regenerate like controls. At the bottom are the number of planarians with the phenotype shown. At 8-10dR, the remaining planarians are either dead (4/124) or have a tiny blastema (23/124) and either died or regenerated later. At 51-68dR, the remaining planarians are either dead (10/93) or have a tiny blastema and died later (5/93)."
NCBI gene IDs:
"cct3A: "
Figure legend: "The graph shows the mitotic numbers of trunks during different time points of regeneration in the starved condition for cct3A RNAi and controls. Error bars are s.d. from the mean and asterisks indicate P &lt; 0.001 (three asterisks), P &lt; 0.01 (two asterisks) and n.s. indicates not significant using two-tailed Student's test with equal variance. n ≥ 9 planarians per time point. Also shown are maximum projections of representative trunks labelled with anti-H3P at different time points of regeneration in the starved condition. On the bottom, the number of planarians with the phenotype shown from the total is displayed. Note that at 50dR planarians show few (a4) or no mitoses (a5). The dashed line delimits the body of the planarian."
NCBI gene IDs:
"cct3A: "
Figure legend: "Maximum projections of representative trunks after FISH for smedwi-1 at different time points of regeneration under starved and feeding conditions. On the bottom, the number of planarians with the phenotype shown from the total is displayed. At 15dR the expression levels are similar. At 30dR some planarians have almost no expression (c5) and at 50dR almost all planarians show no expression (c10 and c11) in starved conditions. Under the feeding condition the expression levels at 30dS are similar. On the bottom, the number of planarians with the phenotype shown from the total is displayed. The dashed line delimits the body of the planarian."
NCBI gene IDs:
"smedwi-1: "
Figure legend: "Volcano plot displaying DEGs in starved cct3A(RNAi) planarians compared to controls at 72hR (q-value &lt; 0.05). Y-axis indicates the negative log10 of the false discovery rate (FDR) (q- value). X-axis indicates the beta values (b), a biased estimator of the fold change. For better visualization, 13 dots with -log10 (q-value) &gt; 20 are not displayed. This includes cct3A with q = 0. Notice that when down-regulating cct3A in starved planarians, xbp1, atf6, bip-1 and a repertoire of ER chaperones are down-regulated, whereas dnajb9, a repressor of the UPR, and other ccts are up-regulated."
NCBI gene IDs:
"bip-1: 
atf6: 
cct3A: 
dnajb9: 
xbp1: "
Figure legend: "Live images show that xbp1/atf6(RNAi) planarians in starved conditions form a minimal blastema when compared to controls while at the feeding condition most of them can regenerate as controls. The remaining planarians in the starved condition are dead by the time point of regeneration shown. In the feeding condition, the remaining planarians at 8-10dR are either dead (13/145) or have a tiny blastema and died or regenerated later (40/145) while at 21-27dR are dead."
NCBI gene IDs:
"atf6: 
xbp1: "
Figure legend: "Maximum projections of representative regenerating trunks after FISH for smedwi-1 in starved conditions. The dashed line delimits the body of the planarian."
NCBI gene IDs:
"smedwi-1: "
Figure legend: "Quantification of the percentage of stem cells in different mitotic phases and the percentage of defective mitotic figures in 72hR anterior blastemas of xbp1/atf6 RNAi and controls in starved conditions after double immunostaining with anti-tyrosine-tubulin and anti-H3P (****P &lt; 0.0001, ***P &lt; 0.001, *P &lt; 0.05, n.s. indicates not significant using two-sided Chi-square test); n ≥ 5 planarians. Representative images are shown. Arrows indicate abnormal organization or number of spindle poles. j8 displays asymmetrical distribution of chromosome content."
NCBI gene IDs:
"atf6: 
xbp1: "
Figure legend: "The Kaplan-Meier curve demonstrates increased survival of cct3A RNAi animals when treated with DTT under starved conditions. Percentages indicate the number of survivals at the indicated time points. Three asterisks indicate p &lt; 0.001 with log-rank (Mantel-Cox) test. Images are representative surviving animals for the different conditions at the displayed time point of regeneration. At the bottom are the number of planarians with the phenotype shown. The rest of planarians are dead at the displayed time point."
NCBI gene IDs:
"cct3A: "
Figure legend: "Volcano plots displaying shRNA-Cct3- and shRNA-luciferase-infected LSK cells cultured either in normal glucose (upper graph) or low glucose conditions (lower graph). Dots represent all the NanoString analyzed transcripts. Red dots are UPR and ER stress related genes. The UPR and ER stress genes significantly down-regulated only under low glucose conditions in shCct3 cells compared to controls are indicated near the lower graph. For better visualization two dots with q ≤ 0.001 have been removed from the volcano plot (see them in Dataset EV4). Y-axis indicates the false discovery rate (FDR) (q- value), and the X-axis indicates the log2 fold changes. The FDR-based method of p-value adjustment was conducted to calculate the q-values by nSolver software using Benjamini-Hochberg methods. Significance is established by q-value &lt; 0.05 and indicated by the dotted horizontal line. n= 3 mice."
NCBI gene IDs:
"luciferase: 
Cct3: 12462"
Figure legend: "The Kaplan-Meier curve demonstrates increased survival of starved cct3A(RNAi) animals when treated with palmitic acid/palmitoylcarnitine (PA/PC). Percentages indicate the number of survivals at the indicated time points. Three asterisks indicate P &lt; 0.001 with log-rank (Mantel-Cox) test."
NCBI gene IDs:
"cct3A: "
Figure legend: "K. Representative data showing OTI CD8+ T cells proliferation  3 days after activation with Listeria-OVA  (left panel, orange) or Listeria  ∆hly -OVA  (right panel, blue) BacB cells. Non-activated naïve CD8+ T cells  (grey) are shown as a negative proliferation  controls."
NCBI gene IDs:
"hly: 987033"
Figure legend: "M. Representative data showing OTI CD8+ T cells proliferation  3 days after activation with Listeria-OVA  (orange), Listeria  ∆hly-OVA  (blue) or Listeria  ∆hly::hly-OVA BacB cells (Purple)."
NCBI gene IDs:
"hly: 987033"
Figure legend: "F. Kaplan Meier survival curve of Rag1-/- mice  after adoptive transfer and bacteria challenge. Data information: Bars in the figure represent the mean. Error bars indicate the SD. Statistical significant differences, analyzed by ANOVA are represented by asterisk; *P&lt;0.05, ***P&lt;0.0005, non-significant differences are marked as (ns). …"
NCBI gene IDs:
"Rag1: 19373"
Figure legend: "H. BacB cells reduce melanoma  growth.  B16 F10 melanoma  cells (4 × 105) were injected s.c. in the mid-right flank of C57BL/6J (WT) host mice  (4 mice/group; treated with BacB or untreated). Once tumors were formed and visible (6 days after imlantation) mice  were treated with Listeria TRP2   BacB cells or with vehicle (PBS) (three consecutive injections in three days). Tumor growth were monitored every 1-3 days. It is shown the mean and the SD of the tumor volume  in each group at the indicated time points. Mice  with tumors ≥ 300 mm3 were sacrified. Data information: Bars in the figure represent the mean. Error bars indicate the SD. Statistical significant differences, analyzed by ANOVA are represented by asterisk; *P&lt;0.05, ***P&lt;0.0005, non-significant differences are marked as (ns). …"
NCBI gene IDs:
"TRP2: 104042"
Figure legend: "B. RIBEYE mutations do not alter mouse survival. Data show surviving post-weaning mice (at &gt;P21) derived from matings between mice heterozygous for the RBEKI allele (dark red) or the RBEKO allele (bright red) normalized for the total number of mice (absolute numbers per genotype/absolute number of all mice per respective breeding strategy) The expected Mendelian ratio is indicated by the dashed line. Statistical analysis using the 2-test revealed no statistical difference between wild-type and mutant mice (RBEKI allele p=0.33; RBEKO allele p=0.11)."
NCBI gene IDs:
"RBE: 
RIBEYE: "
Figure legend: "C. Representative immunoblot of retina homogenates from homozygous RBEWT/WT, RBEKI/KI and RBEKO/KO mice probed with antibodies to CtBP2 (to detect the B-domain of RIBEYE and CtBP2) and to EGFP (to detect GCamP3 in the RIBEYE A-domain GCamP3 fusion protein referred to as RIB-G3)."
NCBI gene IDs:
"RBE: 
RIBEYE: "
Figure legend: "D. Measurements by RT-PCR of the relative abundance of CtBP2 and RIBEYE mRNAs using an assay that simultaneously measures both mRNAs in retina and in brain from control wild-type mice (RBEWT/WT), KI-mice expressing the RIBEYE-A-domain fusion protein with GCamP3 (RBEKI/KI), and KO mice (RBEKO/KO). These measurements were performed to test the relative expression of RIBEYE and CtBP2 in retina, and to examine whether the RIBEYE A-domain KO impairs CtBP2 expression in brain, which expresses little RIBEYE. Assays are based on a qRT-PCR strategy detecting mRNAs containing the spliced connection between exon 2 and 3 which is common to both transcript isoforms (RIBEYE and CtBP2). Statistical analyses were performed using Student's t-test; data are presented as mean ± SEM (***, p&lt;0.001; n=4 mice per genotype)."
NCBI gene IDs:
"RBE: 
RIBEYE: 
CtBP2: 13017"
Figure legend: "E. Representative immunofluorescence labeling of cryostat sections from littermate wild-type and RBEKI/KI mice for EGFP (green, to detect GCamP3 in RIB-G3) and SV2 (red, to label synapses) demonstrates expression of the A-domain/GCamP3 fusion protein in knockin mice (OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, granule cell layer). Scale bar = 5 µm."
NCBI gene IDs:
"RBE: "
Figure legend: "F. Levels of CtBP2 and of synaptic proteins in retina homogenates from littermate RBEWT/WT and RBEKO/KO mice. Levels were determined by quantitative immunoblotting using fluorescently labeled secondary antibodies; results are normalized to loading controls depending on molecular weights (actin, fodrin, VCP, and GDI) and to wild-type controls. Statistical analyses were performed using Student's t-test; data are presented as mean ± SEM (*, p&lt;0.05; n=4 mice per genotype)."
NCBI gene IDs:
"RBE: "
Figure legend: "G. Immunofluoresence labeling for CtBP2 (green, to label RIBEYE) and mGluR6 (red, to label photoreceptorsynapses) in cryostat sections from littermate RBEWT/WT and RBEKO/KOmouseretinas demonstrates that the KO abolishes RIBEYE expression (OPL, outer plexiform layer). Scale bars: 5 µm."
NCBI gene IDs:
"RBE: 
RIBEYE: "
Figure legend: "A. Overview of the synaptic organization of the retina in RBEWT/WT and RBEKO/KOmice. Cryostat sections from littermate mice were labeled by double immunofluorescence for the RIBEYE B-domain (CtBP2; green) and SV2. Scale bar: 20 µm; abbreviations: ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer."
NCBI gene IDs:
"RBE: "