EMBO/SourceData huggingface dataset:
Figure legend: "D Experimental validation of basal DUSP expression in mCFU-E and BaF3-EpoR. Quantitative RT-PCR was performed with all samples on the same plate, allowing a direct comparison of mRNA levels between mCFU-E and BaF3-EpoR cells. Data is normalized to the Rpl32 gene. Ratios of expression in BaF3-EpoR cells compared to mCFU-E cells are shown as box plots. N=10. For details, see Appendix K."
NCBI gene IDs:
"Rpl32: "
Figure legend: "C Model prediction and experimental validation for RSK, AKT, ERK and S6 activation upon RSK overexpression (oe) and 5 U/ml Epo stimulation in 32DEpoR cells. Simulations are based on measured, cell-type-specific protein abundance of 32D-EpoR cells and global kinetic rates estimated from mCFUE and BaF3-EpoR cells. Model predictions are represented by solid lines. Experimental validation data obtained by quantitative immunoblotting represented by filled circles. Error bars represent standard deviation estimated by an error model. Integrated pS6 was significantly higher upon RSK overexpression as compared to 32D-EpoR wild-type (wt) cells, N=4 (lower right panel). Two-Sample t-Test, *** p&lt;0.005."
NCBI gene IDs:
"RSK: 20111"
Figure legend: "D Impact of AKT, Ras or PTEN overexpression on BaF3-induced pS6 dynamics in EpoR and BaF3-PTEN cells. Quantitative AKT upon overexpression of PTEN, Ras, a constitutive active BaF3 protein, or the empty vector control in EpoR cells or BaF3-mCFU-E cells. BaF3-factor deprived mCFU-E cells (5x106 cells per condition) and Epo-immunoblotting cells (1x107 cells per condition) were stimulated with 5 U/ml Epo for indicated time points. Cellular lysates were analyzed by S6 employing sequential reprobing anti-pAKT, anti-ppERK, anti-pS6, anti-Epo and to ensure equal loading with anti-beta-actin antibodies. Detection was performed with chemiluminescence using a CCD camera device (ImageQuant). Quantification of pS6 on the right is depicted as fold change to wild-type samples at 30 minutes after Epo stimulation. Error bars represent standard deviation. oe: overexpression. N=3. Welch Modified Two-Sample t-Test, n.s. = not significant, * p &lt; 0.05"
NCBI gene IDs:
"PTEN: 19211"
Figure legend: "C Analysis of cell-cycle indicator genes upon AKT VIII and U0126 treatment. Growth-factor deprived cells were pretreated for half an hour indicated doses of a single inhibitor, followed by stimulation with 5 U/ml Epo for 0 h and 3 h. The expression of cyclinD2, cyclinG2 and p27 was measured by quantitative RT-PCR and normalized to the Rpl32 gene. Genes were selected based on microarray analysis. Experimental data is shown as fold change to unstimulated cells with mean ± standard deviation, N=3. Welch Modified Two-Sample t-Test, n.s. not significant, * p&lt;0.05, ** p&lt;0.01, *** p&lt;0.005."
NCBI gene IDs:
"Rpl32: 
cyclinD2: 12444
cyclinG2: 12452
p27: 12576"
Figure legend: "Lower panel: Experimental validation of PTEN and SHIP1 overexpression effects on Epo-dependent proliferation. Proliferation was assessed using [3H]-Thymidine incorporation 14 h (mCFU-E) or 38 h (BaF3-EpoR) after retroviral transduction with PTEN or SHIP1 construct for overexpression. Data represented as mean ± standard deviation, N=3. EC50 values are given."
NCBI gene IDs:
"SHIP1: 16331
PTEN: 19211"
Figure legend: ", Protein fold changes of the CcpA mutant over wild type. Log2 fold changes were calculated from LFQ values p values were calculated based on 2-sided two sample t-tests with a FDR threshold of 0.05 and S­0 equal to 1 (Tusher et al, 2001). Proteins outside the significance lines (FDR = 0.05, S­0 = 1) are significantly changed in expression. Example sets of proteins are highlighted and are labeled with their gene names."
NCBI gene IDs:
"CcpA: "
Figure legend: " B, C Relative abundance of sgRNAs in cell populations with high versus low signal were visualized as log2 fold chances for basal as well as activated autophagy conditions for (B) p62 or (C) NDP52. Entire data is reported in Dataset EV1 "
NCBI gene IDs:
"sgRNAs: "
Figure legend: " D-F Validation of TMEM41B. H4 Cas9 cells were infected with sgRNAs targeting TMEM41B or a non-targeting (NT) control, treated with 500 nM AZD8055, 50nM Bafilomycin A1 (BafA1) or DMSO vehicle control for 24 h, and analyzed by immunoblotting. (E, F) p62 and NDP52 band intensities are depicted as total levels relative to vehicle control in H4 Cas9 NT cells (E), or as flux by calculating the ratio in BafA1-treated cells versus vehicle control (F). Data are presented as mean ± SD (n=6 independent experiments) with paired t-test values "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " I HeLa cells were transduced with Cas9 and TMEM41B or NT sgRNAs followed by infection with luciferase-expressing S. typhimurium. Luciferase readings were taken up to 8.5 h post-infection. Results from one representative experiment are presented as mean ± SD (n=8 technical replicates) "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " A H4 Cas9 cells were infected with sgRNAs targeting ATG7, TMEM41B or NT control, treated with 500 nM AZD8055 or vehicle control for 24 h, and analyzed by immunoblotting. B Ratio of LC3-II to LC3-I band intensities are depicted as mean ± SD (n=6 independent experiments) with Wilcoxon test values "
NCBI gene IDs:
"ATG7: 10533
TMEM41B: 440026"
Figure legend: " C H4 Cas9 TMEM41B and NT control cells were probed by LC3B immunostaining and imaged with an automated CV7000 confocal microscope. Scale bar: 20 μm. D The number of LC3 puncta per cell was quantified using Yokogawa Analysis Software (YAS) and depicted as mean ± SD (n=3 technical replicates) "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " H H4 Cas9 TMEM41B and NT control cells were infected with a RFP-DFCP1 expression construct for 72h, fixed, stained with LC3 antibodies and imaged with an automated CV7000 confocal microscope. Arrowheads point at co-localized LC3 and RFP-DFCP1 puncta. Scale bar: 5 µm. I The number of RFP-DFCP1 puncta positive for LC3 was quantified using ImageJ and depicted as mean ± SD (n=10 technical replicates) "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026
DFCP1: 53349"
Figure legend: " J mCherry-GFP-LC3 was expressed in H4 Cas9 TMEM41B KO and NT control cells which were treated with 50nM BafA1 or vehicle control for 24 h, fixed and imaged. Scale bar: 20 μm. The number of mCherry- and GFP-positive puncta per cell was quantified using YAS and are depicted as mean ± SD (n=3 technical replicates) "
NCBI gene IDs:
"Cas9: 
LC3: 81631
TMEM41B: 440026"
Figure legend: " A H4 Cas9 cells stably expressing NT, TMEM41B or ATG7 sgRNAs were stained with BODIPY 493, NBD cholesterol or BODIPY FL C12 probes for 2 h at 37°C and imaged live with an automated CV7000 confocal microscope. Puncta area per cell was quantified using YAS and depicted as mean ± SD (n=4 technical replicates). Scale bar: 20 μm "
NCBI gene IDs:
"ATG7: 10533
TMEM41B: 440026"
Figure legend: " B H4 Cas9 TMEM41B KO and NT control cells were treated overnight with 400 μM BSA-conjugated oleic acid or 0.1% BSA as vehicle control, stained for 2 h with HCS LipidTox Green Neutral Lipid Stain and imaged with an automated Operetta microscope. Scale bar: 20 μm "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " D H4 Cas9 TMEM41B KO and NT control cells were probed by ADRP immunostaining and imaged with an automated CV7000 confocal microscope. Scale bar: 20 μm. E Size of ADRP droplets was quantified with YAS and depicted as mean ± SD (n=3 technical replicates) "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " F Protein level of ADRP was probed by immunoblotting in H4 Cas9 TMEM41B KO and NT control cells. G ADRP band intensities were quantified and depicted as mean ± SD (n=4 independent experiments) with paired t-test values "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026"
Figure legend: " A H4 Cas9 TMEM41B KO and NT control cells were pulsed with the fatty acid analog Red C12, chased in complete medium or upon serum-deprivation, and stained with MitoTracker. Cells were imaged live with an automated CV7000 confocal microscope. Scale bar: 20 μm "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026"
Figure legend: " C-E H4 Cas9 TMEM41B KO and NT control cells were plated in XF96 plates and analyzed using a Seahorse Bioscience XF96. (C) Basal oxygen consumption rates (OCR) and extra cellular acidification rates (ECAR) were measured in cells grown in complete medium. OCR/ECAR ratio is also reported. Data are presented as mean ± SEM (n=30-32 technical replicates) from one representative experiment "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026"
Figure legend: " A H4 Cas9 cells stably expressing N-terminally (Myc-TMEM41B) or C-terminally Myc-tagged TMEM41B (TMEM41B-Myc) were probed by calnexin (CANX) and Myc tag immunostaining and imaged with an automated CV7000 confocal microscope. Scale bar: 20 μm "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026"
Figure legend: " B-D Endogenous TMEM41B locus was tagged with C-terminal Myc using CRISPR-directed homologous recombination in HeLa cells. HeLa knock-in (KI) cells were compared to parental HeLa (-) and HeLa cells stably transduced with a TMEM41B-Myc over-expression (OE) construct. (B) Confocal micrographs of cells stained with antibodies against CANX and Myc confirming ER localization of both KI and OE TMEM41B-Myc. Scale bar represents 20 μm "
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: "(D) PCR analysis with primers binding to TMEM41B last intron and to Myc tag confirming successful targeting of the endogenous TMEM41B locus with Myc (band labeled with asterisk). M=size marker"
NCBI gene IDs:
"TMEM41B: 440026"
Figure legend: " E H4 Cas9 cells and H4 Cas9 cells stably expressing Myc-TMEM41B or TMEM41B-Myc were lysed and subjected to anti-Myc IP. Eluates were analyzed by mass spectrometry. Enrichment of proteins in IPs from Myc-TMEM41B or TMEM41B-Myc cells versus H4 Cas9 cells is depicted as log2 fold changes. Entire data is reported in Dataset EV2 "
NCBI gene IDs:
"Cas9: 
TMEM41B: 440026"
Figure legend: "Left graph reports the tumor volume in NSG mice injected with control (shCTR) and antimiR-9 FaDu cells followed for up to 35 days (n=5 mice/group). Data represent the mean (±SD) and unpaired t-test was used to verify the statistical significance at each time point. On the right, typical images of explanted tumors formed by control (shCTR) and antimiR-9 FaDu cells at necropsy."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "qRT-PCR analyses of normalized miR-9 expression, expressed as fold over the untreated condition, in control (shCTR) and antimiR-9 FaDu cells treated with Cetuximab (CTX) for up to four hours. Data represent the mean (±SD) of three independent experiments performed in duplicate and two-way ANOVA test was used to verify the statistical significance."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "Graph reporting the cell viability of control (shCTR) and antimiR-9 FaDu cells treated with increasing concentration of Gefitinib as indicated and evaluated using the MTS assay. Data represent the mean (±SD) of two independent experiments performed in sextuplicate, and unpaired t-test was used to verify the statistical significance per each dose."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "qRT-PCR analyses of Sp1 expression in control (shCTR) and antimiR-9 FaDu cells transiently transduced with PGK-miR-9 or control vector as indicated. Data represent the mean (±SD) of three independent experiments performed in duplicate and two-way ANOVA with Sidak's multiple comparison test was used to verify the statistical significance. qRT-PCR analyses of Sp1 expression in CAL27 cells transfected with pcDNA miR-9 or control vector. Data represent the mean (±SD) of three independent experiments performed in duplicate and unpaired t-test was used to verify the statistical significance."
NCBI gene IDs:
"PGK: 
miR-9: 407046
Sp1: 6667"
Figure legend: "Graph reporting the normalized Luciferase activity of Sp1 promoter fragments in control (shCTR) or antimiR-9 FaDu cells. Data represent the mean (±SD) of three independent experiments performed in duplicate and unpaired t test was used to verify the statistical significance."
NCBI gene IDs:
"miR-9: 407046
Sp1: 6667"
Figure legend: "On the left, WB analyses of KLF5 and Sp1 expression in control (shCTR) and antimiR-9 FaDu. Histone H3 expression was used as loading control. On the right, protein quantification analyses of KLF5 and SP1 expression normalized on H3 loading control. Data represent the mean (±SD) of three biological replicates and unpaired t test was used to verify the statistical significance."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "Left, WB analyses of the indicated protein expression in control (shCTR) and antimiR-9 FaDu cells not irradiated (NIR) or treated with 5Gy IR and allowed to repair for the indicated hours (h). Tubulin was used as loading control. On the right, protein quantification analyses of KLF5 and Sp1 expression normalized on tubulin loading control. On the right, graphs report the quantification of the indicated proteins normalized on tubulin expression. Data are expressed as mean (±SD) of three independent experiments and unpaired t test was used to calculate the statistical significance at time point."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "Left panel reports typical immunofluorescence images of control (shCTR) or antimiR-9 FaDu cells, not irradiated (NIR) and analyzed 1, 4 or 8 hours after 2Gy IR (γH2AX green, pS10-H3 red, nuclei in blue). Graphs report the percentage of γH2AX (middle) and pS10-H3 (right) positive cells. Data represent the mean (±SD) of three independent experiments in which at least 10 randomly selected fields were evaluated. Unpaired t test was used to calculate the statistical significance at each time point."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "Kaplan-Mayer curve evaluating the overall survival of HNSCC patients treated with RT+Cetuximab (CTX) combination included in the TCGA dataset, segregated on the expression of miR-9 in the primary tumor (Low expression &lt;75819 reads n=8; High expression ≥75819 reads n=23). Number of evaluated samples (n) and p value are reported in the graph. Statistical significance was calculated with long-rank test."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "Kaplan-Mayer curve evaluating the progression free survival of HNSCC patients treated with RT+Cetuximab (CTX) combination at the CRO-Aviano National Cancer Institute and at the University Cattolica segregated based on miR-9 expression in primary tumors, defined as the expression in above (high expression n=18) or below (low expression n=17) the median expression, as defined by ddPCR. Hazard Ratio (HR) and statistical significance were calculated with long-rank (Mentel-Cox) test and are reported in the graph."
NCBI gene IDs:
"miR-9: 407046"
Figure legend: "B. Representative images (upper) and QIBC analysis (lower) (solid lines, median; dashed lines, quartiles; &gt;10000 cells analyzed per condition) of Ub(G76V)-GFP  expression in stable U2OS/Ub(G76V)-GFP  cells treated or not with p97i for 4 h. Data information: Data are representative of three independent experiments with similar outcome."
NCBI gene IDs:
"GFP: 
Ub: 6233///7311///7314///7316"
Figure legend: "D. DOX-treated U2OS/shUb/HA-Ub(WT) and U2OS/shUb/HA-Ub(K27R) cell lines were transfected with shUb-resistant Ub(G76V)-GFP construct and treated or not with  p97i for 4 h. Cell extracts were subjected to GFP IP followed by  immunoblotting  with indicated antibodies. Data information: Data are representative of three independent experiments with similar outcome."
NCBI gene IDs:
"GFP: 
HA: 
Ub: 6233///7311
Ub: 6233///7311///7314///7316
Ub: 7311///6233
Ub: 7314///7316///6233///7311"
Figure legend: "E. Immunoblot  analysis of DOX-treated U2OS/shUb/HA-Ub cell lines treated or not with MG132 for 4 h. Data information: Data are representative of three independent experiments with similar outcome."
NCBI gene IDs:
"HA: 
Ub: 6233///7311///7314///7316
Ub: 7311///6233"
Figure legend: "G. DOX-treated U2OS/shUb/HA-Ub(WT) and U2OS/shUb/HA-Ub(K27R) cell lines transfected with indicated Ub(G76V)-GFP expression constructs were subjected to  GFP IP under denaturing conditions followed by immunoblotting  with indicated antibodies. Data information: Data are representative of four (G) independent experiments with similar outcome."
NCBI gene IDs:
"GFP: 
HA: 
Ub: 6233///7311///7314///7316
Ub: 7311///6233
Ub: 7316///7314///7311///6233"
Figure legend: "A. FLAG IPs from U2OS  cells transfected with indicated FLAG- tagged expression constructs were incubated with purified K27 di-Ub and analyzed by immunoblotting. Data information: Data are representative of three (A independent experiments with similar outcome."
NCBI gene IDs:
"FLAG: "
Figure legend: "I. U2OS/Ub(G76V)-GFP and U2OS/Ub(G76V)-20AA-GFP  cell lines were transfected or not with FLAG-UCHL3  C95S expression construct, treated with MG132  for 2 h and subjected to GFP IP  followed by immunoblotting. Data information: Data are representative of three independent experiments with similar outcome."
NCBI gene IDs:
"FLAG: 
GFP: 
Ub: 7316///7314///7311///6233
UCHL3: 7347"
Figure legend: "A. Schematic diagram of sucrose  density gradient ultracentrifugation for  RNC isolation, and PCR  verification of the 12 screened lncRNA  in both RNC-RNA and total RNA from two groups of  CRC cells, among which the translation level of lnc-AP (marked with a green box) was the most notably dysregulated in both groups of drug-resistant cells (n = 3, biological replicates, mean±SEM, t test). Data information: * for P &lt; 0.05; ** for P &lt; 0.01; NS for no significance."
NCBI gene IDs:
"lnc-AP: 
lncRNA: "
Figure legend: "B. PCR analysis of  lnc-AP in serum samples from  oxaliplatin-resistant (PD, n = 15) and -sensitive (PR, n = 9) CRC patients (mean±SEM, t test)."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "C. In the public database lncCAR, high expression level of lnc-AP was correlated with long overall survival in CRC patients."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "E. PCR  and WB analysis of  HEK293T cells transfected with either  lnc-AP-Flag OE plasmid (n = 3, biological replicates, mean±SEM, Dunnett-t test). F. PCR  and WB analysis of HCT116/L-OHP  and SW480/L-OHP cells transfected with either lnc-AP-Flag OE plasmid (n = 3, biological replicates, mean±SEM, Dunnett-t test). Data information: * for P &lt; 0.05; ** for P &lt; 0.01; NS for no significance. Control referred to the corresponding plasmid vector."
NCBI gene IDs:
"Flag: 
lnc-AP: "
Figure legend: "J.  IF detection of  pep-AP in HCT116/L-OHP and  SW480/L-OHP cells transfected with either HA-lnc-AP OE plasmid. Scale bar, 10 µm."
NCBI gene IDs:
"HA: 
lnc-AP: "
Figure legend: "B. CCK-8 assay of inhibition ratio by L-OHP in two groups of  CRC cells with down- or up-regulation of  lnc-AP  (n = 3, biological replicates, mean±SEM). Data information: * si-NC was the abbreviation of commercial normal control of siRNA."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "C.  IF detection of H2AFX for  DNA damage by L-OHP in two groups of CRC cells with down- or up-regulation of   lnc-AP, and nuclei were stained with DAPI (n = 3, biological replicates, mean±SEM, Dunnett-t test)."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "G. Verification of the  interaction between  CEBPA and the upstream region of  AP002387  via ChIP assay followed by  PCR (n = 3, biological replicates, mean±SEM, t test). Data information: * for P &lt; 0.05; ** for P &lt; 0.01"
NCBI gene IDs:
"AP002387: "
Figure legend: "H.  PCR analysis of lnc-AP attenuation and restoration in HCT116  and SW480 cells (n = 3, biological replicates, mean±SEM, Dunnett-t test). Data information: * for P &lt; 0.05; ** for P &lt; 0.01; NS for no significance. Control referred to the corresponding plasmid vector and si-NC was the abbreviation of commercial normal control of siRNA."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "J. CCK-8 assay of inhibition ratio by L-OHP in  HCT116 and  SW480 cells with  lnc-AP/pep-AP attenuation and restoration (n = 3, biological replicates, mean±SEM). Data information: * si-NC was the abbreviation of commercial normal control of siRNA."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "D. Survival analysis correlated with TALDO1 using TCGA data. Upper: the Kaplan curve of overall survival probability for patients with high or low level of TALDO1. Lower: the  expression graph of TALDO1 in  patients who were dead or not."
NCBI gene IDs:
"TALDO1: 6888"
Figure legend: "F. MMP detection with down- or up-regulation of   lnc-AP/pep-AP in two groups of  CRC cells. Scale bar, 10 µm."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "C. Flow cytometry of the cell apoptosis ratio under  L-OHP with down- or up-regulation of  lnc-AP/pep-AP in two groups of CRC cells, which was quantified in bar charts on the right (n = 3, biological replicates, mean±SEM, Dunnett-t test). Data information: * for P &lt; 0.05; ** for P &lt; 0.01; NS for no significance. Control referred to the corresponding plasmid vector and si-NC was the abbreviation of commercial normal control of siRNA."
NCBI gene IDs:
"lnc-AP: "
Figure legend: "Composite immunofluorescent images showing GFP expression of whole-ear sections from DKO*-mT/mG mice at day 5, 7, 15 and 30. Increased GFP expression is shown at day 7 followed by progressive decrease of GFP+ keratinocytes (white dotted line represents basal layer, and red dotted line represents outermost skin layer). n=3 per time point. Quantification analysis of GFP expression (top) and epidermal thickness (bottom) of DKO* mice at different time points during psoriasis-like disease progression. n=6 per time point. Statistical significance *p&lt;0.05, **p&lt;0.01, ***p&lt;0.001 (t-student two tailed-test relative to control group)."
NCBI gene IDs:
"mG: 
mT: "
Figure legend: "Intravital confocal time-lapse imaging of non-mutant Tomato keratinocytes and mutant GFP keratinocytes of DKO*-mT/mG at day 7 after first tamoxifen injection. Dotted circles emphasize areas in which mutant GFP+ keratinocytes are replaced by non-mutant Tomato+ keratinocytes."
NCBI gene IDs:
"mG: 
mT: "
Figure legend: "Percentage of GFP+ area eliminated during intravital confocal time-lapse imaging at day 5, 7 and 15 in DKO*-mT/mG mice (Time-lapse 1:8h). Positive value: Area of GFP increased. Negative value: Area of GFP reduced."
NCBI gene IDs:
"mG: 
mT: "
Figure legend: "Fluorescence imaging of DKO*-mT/mG ear skin at day 30 after first tamoxifen injection shows that remaining mutant GFP+ keratinocytes reside along the hair follicles. White dotted line separates epidermis and dermis. White arrows represent GFP+ hair follicles."
NCBI gene IDs:
"mG: 
mT: "
Figure legend: "Intravital confocal time-lapse imaging of DKO*-mT/mG at day 15 after first tamoxifen injection. Mutant GFP+ Keratinocytes (white arrows) are maintained around hair follicles."
NCBI gene IDs:
"mG: 
mT: "
Figure legend: "Ear pictures of control, DKO*, and DKO*K15 mice after 15 days of induction show clear signs of inflammation and psoriatic-like scales in both models."
NCBI gene IDs:
"K15: 16665"
Figure legend: "Representative images of hematoxylin and eosin (H&amp;E) staining of ear sections from control, DKO* and DKO*K15 mice."
NCBI gene IDs:
"K15: 16665"
Figure legend: "Ear thickness measurement at different time points during psoriasis-like development in control, DKO* and DKO*K15 mice. n &gt; 5 per group. Statistical significance *p&lt;0.05, **p&lt;0.01, ***p&lt;0.001 (t-student two tailed-test relative to control group)."
NCBI gene IDs:
"K15: 16665"
Figure legend: "FACS quantification of CD45+ cells from ear skin of control, DKO* and DKO*K15 mice at different time points during psoriasis-like development. n &gt; 5 per group. Statistical significance *p&lt;0.05, **p&lt;0.01, ***p&lt;0.001 (t-student two tailed-test relative to controls)."
NCBI gene IDs:
"K15: 16665"
Figure legend: "Quantification of IL-17A, IL-6 and LCN2 production in sera of control, DKO* and DKO*K15 mice at day 30 of psoriasis-like disease by ELISA. n &gt; 4 per group. Statistical significance *p&lt;0.05, **p&lt;0.01, ***p&lt;0.001 (t-student two tailed-test relative to controls)."
NCBI gene IDs:
"K15: 16665"