EMBO/SourceData huggingface dataset:
Figure legend: "The responses of th acetate sensors during growth in shake flasks are shown"
NCBI gene IDs:
"sensors: "
Figure legend: "(e) The responses of a 3-input, 2-output circuit are shown. (f) Shown are the circuit (left) and genetic diagram (right) of the circuit corresponding to part e. In the genetic diagram, the dashed line and * indicates a second copy of the PgluA7 promoter that drives rfp expression and is repressed by PhlF via an immediately downstream PhlF operator. (g) The response of the circuit in parts e and f to different combinations of stimuli under the same conditions as Figure 1 (Methods). The (+) and (-) indicate whether the output promoter of each sensor is active under those conditions. Bars where the circuit is predicted to be on are shown in grey and white when predicted to be off"
NCBI gene IDs:
"PgluA7: 
PhlF: 
sensor: "
Figure legend: "(b) Reduction of fluorescence of RFP by the different mechanisms of repression after 18 hours of growth (Methods). The inducers are either 1 mM IPTG (sRNA) or 25 μM DAPG (sgRNA, mf-LON). sgRNA and mf-LON are co-transcribed on a single transcript, processed by ribozymes (Appendix Figure S13). (c) The dynamics of repression by each of the mechanisms is shown. Empty circles are uninduced and black circles are induced (1 mM IPTG or 25 µM DAPG) at the 2-hour time point (dashed line) (Methods)"
NCBI gene IDs:
"LON: "
Figure legend: "(f) The impact on acetate production for a double mutant where poxB is complemented on a BAC (Methods). Note that complementation causes a ~3-fold reduction in acetate compared to WT in part d. N-ter and E170 refer to the location of the SuMMV tag. (g) Reduction of acetate production by the expression of SuMMV from an DAPG-inducible promoter (- no inducer, + 25 µM). The PoxB variant with the degron inserted at position E170 is either carried on a BAC or at its native location in the genome"
NCBI gene IDs:
"SuMMV: 
poxB: 946132
PoxB: 946132"
Figure legend: "(b) The transcription of poxB over time (E. coli MG1655∆glnL), as calculated from RNA-seq data (Methods). The colored bars indicate the times at which the glucose/acetate sensors will be on based on metabolite measurements. It should be noted that these are right-shifted compared to Figure 2 due to slower growth of the tested strains"
NCBI gene IDs:
"sensors: 
glnL: 948360
poxB: 946132"
Figure legend: "(c) The production of acetate is shown over time for E. coli MG1655∆glnL∆pta poxB::E170 (black) as compared to the same strain containing the complete circuit (green). A version of the circuit in which the sgRNA is targeted to rfp (not present in the system) and is tested in MG1655∆glnL∆pta containing an untagged poxB as a control (red). Empty circles connected by the dashed line represent MG1655∆glnL∆pta∆poxB"
NCBI gene IDs:
"glnL: 948360
poxB: 946132
pta: 946778"
Figure legend: "(e) The transcription of pta over time (E. coli MG1655∆glnL), as calculated from RNA-seq data (Methods). The colored bars indicate the times at which the glucose/oxygen sensors will be on based on metabolite measurements"
NCBI gene IDs:
"sensors: 
glnL: 948360
pta: 946778"
Figure legend: "(f) The production of acetate is shown over time for E. coli MG1655∆glnL∆poxB pta::pdt3 as compared to a strain containing the complete circuit (green) tested in same strain. A version of the circuit in which the sgRNA is targeted to rfp (not present in the system) and is tested in MG1655∆glnL∆poxB containing an untagged pta as a control (red) Empty circles connected by the dashed line represent MG1655∆glnL∆pta∆poxB"
NCBI gene IDs:
"glnL: 948360
poxB: 946132
pta: 946778"
Figure legend: "(H, I) Enzymatic activity of FBL is not required for cell proliferation. Colony formation assays were conducted to investigate the role of enzymatic activity in cell proliferation. FBL knockdown HCT116 or A549 cells with ectopic expression of FBL or the catalytically inactive mutant (FBL-E191A/ D236A) were used, with a bar graph showing the relative number of colonies per well (mean ± SD). All cells were allowed to form colonies for 10 days and representative images of colonies in plates stained with Giemsa were displayed. The bar graphs present data as mean ± SD from three independent experiments. The statistical significance was determined using one-way ANOVA. ns denotes no statistical significance, * indicates P &lt; 0.05, *** indicates P &lt; 0.001."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(A, B) Knockdown of FBL results in increased cellular sensitivity to DNA damage treatment. Cell viability analysis was performed on control (shNC) and shFBL-HCT116/shFBL-A549 cells treated with indicated concentrations of 5 μM MMC using CCK-8 assays. Each data point represents the mean ± SD from three replicates. The statistical significance was determined using Student's t-test. ***p &lt; 0.001."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(D-F) Immunofluorescence staining showed the formation of γH2AX and BRCA1 foci in shFBL and shNC HCT116 cells treated with 5 μM MMC or mock treatment. The scale bar represents 10 μm. The (E) and (F) panel displays quantification of the (D) panel: indicating the number of γH2AX or BRCA1 foci per cell (n≥100 cells). Data are shown as the mean ± SD. The statistical significance was determined using one-way ANOVA, with ns indicating no statistical significance, *** indicating P &lt; 0.001."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(B). Co-IP analyses of GFP- tagged FBL and SFB-tagged YBX1 in HCT116 cells using indicated antibodies. HCT116 cells were transfected with vectors encoding GFP-FBL and SFB-YBX1. Cells were lyzed with NETN300 buffer. Cell extracts were examined by IP and western blot with indicated antibodies."
NCBI gene IDs:
"GFP: 
FBL: 2091
YBX1: 4904"
Figure legend: "(E) The N-terminal GAR domain is essential for the interaction between FBL and YBX1. Upper panel, a schematic representation of wild-type FBL with the GAR domain and methyltransferase domain (MTase). Lower panel, Co-IP analyses of GFP-tagged FBL deletion mutants and SFB-tagged YBX1 in HCT116 cells."
NCBI gene IDs:
"GFP: 
FBL: 2091
YBX1: 4904"
Figure legend: "(F) The B/A repeat domain of YBX1 is essential for the interaction between YBX1 and FBL. Upper panel, a schematic representation of wild-type YBX1 with the Alanine/proline rich domain, Cold shock domain and B/A repeat domain. Lower panel, co-IP analyses of GFP-tagged YBX1 deletion mutants and SFB-tagged FBL in HCT116 cells."
NCBI gene IDs:
"GFP: 
FBL: 2091
YBX1: 4904"
Figure legend: "(C) Subcellular localization of YBX1/FBL was confirmed by immunofluorescence staining following MMC (5 μM, overnight) or cisplatin (25 μM, 2 hours) treatment in shFBL and shNC cells. Scale bar, 10 μm."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(E) The distribution of YBX1 proteins in the nuclear and cytoplasmic fractions of control or FBL KD HCT116 cells after 5 μM MMC incubation overnight were determined by western blotting assays. H3 was used as a nuclear control. GAPDH was used as a cytoplasmic control."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(F) The protein contents of YBX1 in the nuclear and cytoplasmic fractions in FBL KD HCT116 cells reconstituted with wild-type FBL or deletion mutants of FBL with 5 μM MMC treatment overnight were detected by western blotting assays with indicated antibodies."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(A) A Volcano plot of differentially expressed gene analysis results for RNA-seq data comparing FBL KD HCT116 cells (n = 3) to control cells (n = 3). The dots for significant upregulated or downregulated genes were colored in red or blue, respectively."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "(E) The mRNA and protein levels of BRCA1 and RAD51 were validated by RT-qPCR and western blot assays using FBL KD HCT116 cells or control cells. Ct values were normalized to GAPDH. The bar graphs present data as mean ± SD from three independent experiments. The statistical significance was determined using Student's t-test. ***P &lt; 0.001."
NCBI gene IDs:
"BRCA1: 672
FBL: 2091
RAD51: 5888"
Figure legend: "(F) The mRNA and protein levels of BRCA1 were validated by RT-qPCR and Western blotting assays using YBX1-silenced HCT116 cells or control cells. Ct values were normalized to GAPDH. The bar graphs present data as mean ± SD from three independent experiments. The statistical significance was determined using Student's t-test. ***P &lt; 0.001."
NCBI gene IDs:
"YBX1: 4904"
Figure legend: "(C) HE staining of tumor tissues. Scale bar, 50 µm. (D Representative images of immunohistochemical staining showing BRCA1 and γH2AX expression levels in MMC-treated and untreated xenograft tumors driven by control or FBL KD HCT116 cells. panel displays quantification of the (D) panel: showing BRCA1 and γH2AX expression levels. Scale bar, 25 µm. Graphs represent the mean ± SD (n = 3 mice in each group). The statistical significance was determined using one-way ANOVA. *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001."
NCBI gene IDs:
"FBL: 2091"
Figure legend: "The rapZ  mutants were expressed from plasmids under control of the PBAD promoter (induction with arabinose, repression by glucose) and tested for the ability to complement a strain lacking the chromosomal rapZ  gene in (b) Northern blotting experiment detecting GlmZ  (top panel) and 5S rRNA (bottom panel; loading control) to assess the degree of GlmZ  cleavage triggered by the RapZ  variants. Processed GlmZ  is indicated with an asterisk. Strains Z8 (wild-type, lanes 1, 2) and Z28 (∆rapZ, all other lanes were used. Strain Z28 carried plasmid pBAD33 (lanes 3, 4; empty vector control = VC) or derivatives triggering synthesis of the indicated RapZ  variants"
NCBI gene IDs:
"5S rRNA: 
GlmZ: 2847678
rapZ: 947727
RapZ: 947727"
Figure legend: "The rapZ  mutants were expressed from plasmids under control of the PBAD promoter (induction with arabinose, repression by glucose) and tested for the ability to complement a strain lacking the chromosomal rapZ  gene in (c) GlmS  protein (MW = 66.9 kDa) levels in the same cultures as revealed by  SDS-PAGE  of total protein extracts followed by Coomassie blue staining. Strains Z8 (wild-type, lanes 1, 2) and Z28 (∆rapZ, all other lanes were used. Strain Z28 carried plasmid pBAD33 (lanes 3, 4; empty vector control = VC) or derivatives triggering synthesis of the indicated RapZ  variants"
NCBI gene IDs:
"rapZ: 947727
RapZ: 947727"
Figure legend: "The rapZ  mutants were expressed from plasmids under control of the PBAD  promoter (induction with arabinose, repression by glucose) and tested for the ability to complement a strain lacking the chromosomal rapZ  gene in (d)  β-Galactosidase activities produced by the same cultures and replicates (mean values and standard deviations are shown). Cells carry a  glmS'-lacZ  fusion on the chromosome, which requires base-pairing with sRNA GlmZ  for high expression. Strains Z8 (wild-type columns 1, 2) and Z28 all other columns) were used. Strain Z28 carried plasmid pBAD33 columns 3, 4; empty vector control = VC) or derivatives triggering synthesis of the indicated RapZ  variants"
NCBI gene IDs:
"lacZ: 
GlmZ: 2847678
rapZ: 947727
RapZ: 947727"
Figure legend: "(H-I) EHD1 depletion prevents CP110 degradation upon serum starvation. (H) Mock-transfected RPE-1 cells or EHD1 siRNA-transfected RPE-1 cells were grown in media containing serum, or serum starved for 4 h in the absence or presence of MG132, and then lysed, separated by SDS-PAGE and immunoblotted with anti-CP110 antibodies (upper panel) or anti-actin antibodies (loading control; lower panel). Validation of EHD1 depletion is shown in the right panel. (I) Graph displaying densitometric analysis of the intensity of the CP110 bands shown in H normalized to actin (means and p-values are representative of 3 independent experiments). Normal distribution was determined by the Shapiro-Wilk normality test."
NCBI gene IDs:
"EHD1: 10938"
Figure legend: "(A-B) PCM1-depletion impedes CP110 ubiquitination upon serum starvation. (A) Mock-transfected RPE-1 cells were maintained in media with serum, and both mock-transfected and PCM1 siRNA-transfected cells were serum starved for 4 h in the presence of MG132 prior to lysis and immunoblotting with anti-CP110 antibodies (second panel from top), or first immunoprecipitated with anti-CP110 antibodies and then immunoblotted with antibodies to detect ubiquitinated CP110 (top panel). Bottom panels depict the efficacy of PCM1 depletion upon PCM1 siRNA-transfection, with actin as a loading control. (B) Graph displaying densitometric analysis of ubiquitinated CP110 levels (from the upper panel of A) normalized to total CP110 immunoprecipitated. Normal distribution was determined by the Shapiro-Wilk normality test."
NCBI gene IDs:
"PCM1: 5108"
Figure legend: "(D-G) Serum starved mock-transfected RPE-1 cells on cover-slips were fixed and immunostained with antibodies directed against acetylated tubulin and CP110 and display primary cilia generation (marked by acetylated tubulin; D, F and inset in G) and removal of CP110 from the m-centriole (E-G; see arrow marking CP110 only on the daughter centriole). (H-K) Serum starved PCM siRNA-transfected RPE-1 cells on cover-slips were fixed and immunostained with antibodies directed against acetylated tubulin and CP110 and display limited ciliogenesis (H, J and inset in K) and failure to remove CP110 from the m-centriole (I-K; see arrows identifying CP110 on both centrioles)."
NCBI gene IDs:
"PCM: 5108"
Figure legend: "EHD1 regulates the distribution of centriolar satellites to the centrosomal region. Mock-transfected RPE-1 cells on cover-slips were serum starved and immunostained with antibodies against acetylated tubulin and PCM1 and EHD1 siRNA-transfected cells on cover-slips were serum starved and immunostained with antibodies against acetylated tubulin and PCM1 The p-values are calculated for all non-ciliated and ciliated mock-transfected cells compared to all EHD1 siRNA non-ciliated and ciliated cells. Note that as expected, among the EHD1-depleted cells, there are minimal cells that display ciliation."
NCBI gene IDs:
"EHD1: 10938"
Figure legend: "(A) Validation of siRNA depletion. RPE-1 cells were mock-transfected or transfected with siRNA oligonucleotides to impair translation of Cullin3, HERC2, or MIB1. 72 h later, the cells were lysed, subjected to SDS-PAGE and immunoblotted. Immunoblotting with anti-actin antibodies was done as a loading control."
NCBI gene IDs:
"Cullin3: 8452
HERC2: 8924
MIB1: 57534"
Figure legend: "(B) HERC2 or MIB1 depletion impairs CP110 ubiquitination. RPE-1 cells were grown in serum (first lane from left), or with MG132 in the absence of serum for 4 h (second lane from left), transfected with Cullin3 siRNA-oligonucleotides and treated with MG132 in the absence of serum for 4 h (third lane from left), transfected with HERC2 siRNA-oligonucleotides and treated with MG132 in the absence of serum for 4 h (fourth lane from left), or transfected with MIB1 siRNA-oligonucleotides and treated with MG132 in the absence of serum for 4 h (fifth lane from left). Cells were lysed and immunoprecipitated with anti-CP110 antibodies, and the resultant immunoprecipitates were immunoblotted with anti-ubiquitin to identify ubiquitinated CP110 (upper panel). The blot was then stripped and re-immunoblotted with anti-CP110 to reveal the amount of CP110 pulled-down from the lysate (lower panel)."
NCBI gene IDs:
"Cullin3: 8452
HERC2: 8924
MIB1: 57534"
Figure legend: "(B-M) (B-D) Mock-transfected cells, (E-G) MIB1 siRNA-transfected cells, (H-J) HERC2 siRNA-transfected cells, or (K-M) MIB1 and HERC2 siRNA-transfected cells on cover-slips were fixed and immunostained with antibodies against acetylated tubulin (insets; C, F, I, L: merged field; B, E, H, K) and CP110 (insets; D, G, J, M: merged field; B, E, H, K). Bars (B, E, H, K), 10 mm. Bars (C, D, F, G, I, J, L, M), 2 μm."
NCBI gene IDs:
"HERC2: 8924
MIB1: 57534"
Figure legend: "(A) EHD1 is required for the interaction between HERC2 and CP110. RPE-1 cells were mock-transfected or transfected with EHD1 siRNA oligonucleotides for 72 h. Cells were lysed and immunoprecipitated with anti-CP110 or beads only (control) and separated by SDS-PAGE along with 7% of the lysate (input). After transfer to nitrocellulose, antibodies were used to detect CP110 (lower panel) and HERC2 (upper panel)."
NCBI gene IDs:
"EHD1: 10938"
Figure legend: "(G-H) Representative micrographs of RPE-1 cells on cover-slips that were mock-transfected (G) or EHD1 siRNA-transfected (H) and immunostained with antibodies to acetylated tubulin (red) or HERC2 (green). Dashed yellow regions of interest highlight the centrosomal area. Arrows denote the HERC2 signal observed in each micrograph. Bars, 1 μm."
NCBI gene IDs:
"EHD1: 10938"
Figure legend: "(A-D) RPE-1 cells on coverslips were mock-transfected (A), transfected with CP110 siRNA-oligonucleotides (B) transfected with HERC2 siRNA-oligonucleotides (C), or transfected with both CP110 and HERC2 siRNA-oligonucleotides (D). Cells were fixed and immunostained with acetylated tubulin to detect primary cilia (yellow arrows). Bars, 10 μm. : Graphs show standard deviation and p-values from 3 independent experiments. The micrographs (A-D) are representative ones from the 3 individual biological experiments. More than 50 cells were quantified in each experiment, although fewer ciliated cells were observed and measured under the HERC2 knock-down condition."
NCBI gene IDs:
"CP110: 9738
HERC2: 8924"
Figure legend: "(E) Immunoblot demonstrating the efficacy of depletion for CP110 (middle panel), HERC2 (top panel), and simultaneous CP110 and HERC2 depletion (middle and top panels). Actin was used as a loading control (bottom panel). : Graphs show standard deviation and p-values from 3 independent experiments. immunoblots (E) are representative ones from the 3 individual biological experiments."
NCBI gene IDs:
"CP110: 9738
HERC2: 8924"
Figure legend: "A Levels of VEGF-A mRNA in the intestinal tissues from  COVID-19 patients (n=5) or healthy controls (n=5) by RNA-seq. Data information: All data are shown as mean ± SD. For (A), P values are determined by Student's t-test"
NCBI gene IDs:
"VEGF-A: 7422"
Figure legend: "A qRT-PCR analysis of levels of VEGF mRNA in HUVEC treated with Control-Fc or Spike RBD-Fc. For each group, n=3. Data are from 3 independent biological experiments. Data information: All data are shown as mean ± SD. For (A) P values are determined by Paired Student's t-test"
NCBI gene IDs:
"VEGF: 7422"
Figure legend: "Representative grey-scale images of primary rat hippocampal neurons (DIV 10) transfected with GFP and the indicated miRNA mimics. Quantification of the mean number of intersections by Sholl analysis. GFP-only transfected conditions were set to one in each experiment."
NCBI gene IDs:
"GFP: "
Figure legend: "Representative grey-scale images of GFP-transfected Cacna1c+/+ (WT) or Cacna1c+/- primary rat hippocampal neurons (DIV 10). Scale bars = 50 μm.   Quantification of the mean number of intersections by Sholl analysis. Data are represented as scattered dot plots with bar, mean±S.D. (n=3 independent experiments; Unpaired two-sample t-Test, **p=0.0096). Fold changes represent changes in dendritic complexity relative to the control condition.  "
NCBI gene IDs:
"GFP: 
Cacna1c: 24239"
Figure legend: "Representative images of DIV 10 hippocampal neurons co-transfected with control or miR-499-5p mimics and a pMT2-CACNB2 expression plasmid (CACNB2). Scale bars = 50 μm.   Quantification of the mean number of intersections by Sholl analysis. Data are represented as scattered dot plots with bar, mean±S.D. (n=3 independent experiments; Two-way ANOVA: no main effect of the CACNB2 transfection p=0.5027 or the miRNA mimics p=0.0805, main effect of the CACBN2 transfection by miRNA mimics interaction p=0.0213, Tukey's HSD: *p=0.0303). Fold changes represent the changes in dendritic complexity of transfected neurons compared to non-treated control neurons. ns = not significant.  "
NCBI gene IDs:
"CACBN2: 116600
CACNB2: 116600
miR-499-5p: 100314091"
Figure legend: "A) Representative images of DIV 19 rat hippocampal neurons co-transfected with GFP (green channel) and Cav1.2-HA (red channel), together with either control or miR-499-5p mimics. After 12-13 days of expression, labeling with Anti-HA antibodies was performed in live conditions to identify cell surface Cav1.2 channels. Whole cells: scale bars = 20 μm; cell body and dendrite insets: scale bars= 5 μm. B) Quantification of the area occupied by surface Cav1.2 fluorescence normalized to the total cell area (GFP fluorescence) from non-permeabilized neurons transfected as in A). Data are represented as scattered dot plots with bar, mean±S.D. (n=4 independent experiments; Paired two-sample t-Test *p=0.0318)."
NCBI gene IDs:
"GFP: 
HA: 
Cav1.2: 24239
miR-499-5p: 100314091"
Figure legend: "D) Representative Western blot images of CACNB2 (upper panel) and GAPDH (lower panel) protein expression levels in the hippocampus of WT rats and Cacna1c +/- rats injected with the AAV-Control or AAV-miR-499 hairpin viruses. GAPDH was used as a loading control E) Quantification of CACNB2 Western blots using hippocampal protein lysate from wild type rats injected with either AAV-control or AAV-miR-499. Data are represented as box plot with whiskers and data points (+: mean, line: median; whiskers: minimum and maximum values). (*p=0.0103, Unpaired two-sample t-Test; n=7 rats in the AAV-Control group, n=6 rats in the AAV-miR-499 group). F) Quantification of CACNB2 Western blots using hippocampal protein lysate from Cacna1c +/- rats injected with either AAV-control or AAV-miR-499. Data are represented as box plot with whiskers and data points (+: mean, line: median; whiskers: minimum and maximum values). (**p=0.0044, Unpaired two-sample t-Test; n=8 rats in the AAV-Control group, n=7 rats in the AAV-miR-499 group)."
NCBI gene IDs:
"Cacna1c: 24239
miR-499: 100314091"
Figure legend: "miR-499-5p qPCR analysis of total RNA isolated from PBMCs of control (female= 26, male= 31), BD (female= 26, male= 37), or MDD (female= 18, male=24) subjects. Wilcoxon rank sum test after correction for age and antidepressant treatment (linear model of the form Fold Change ~ Group*Sex + Age + Antidepressant treatment). 2-way ANOVA with correction for sex, age and antidepressant treatment (linear model of the form Fold Change ~ Group*Sex + Age + Antidepressant treatment). Control vs. BD: ****p=8.89e-07; control vs. MDD: n.s. p=0.12674. Data are presented as violin plots with median, quartiles and data points."
NCBI gene IDs:
"miR-499-5p: 574501"
Figure legend: "miR-499-5p qPCR analysis of total RNA isolated from PBMCs of control (female= 8, male= 10) and SZ (female= 8, male= 15) subjects. 2-way ANOVA, Main effect Sex: p=0.9785; main effect Group: p= 0.0924; main effect Interaction: p= 0.9802. Tukey's HSD: p=0.0924, ns. Data are presented as violin plots with median, quartiles and data points."
NCBI gene IDs:
"miR-499-5p: 574501"
Figure legend: "miR-499-5p qPCR analysis of total RNA isolated from PBMCs of control (female= 26, male= 31), BD I (female= 9, male= 9), or BDI II (female= 12, male=16) subjects. 2-way ANOVA, Main effect Sex: p=0.174; main effect Group: ****p=4.07e-09; Interaction Group x Sex: p=0.311. Tukey's HSD: control vs. BDI: ****p=0.0000037. control vs. BDII:p=0.0000002. Data are presented as violin plots with median, quartiles and data points."
NCBI gene IDs:
"miR-499-5p: 574501"
Figure legend: "miR-499-5p qPCR analysis of total RNA isolated from PBMCs of control subjects (female= 26, male= 31), and BD subjects in different mood states (depressive (female= 7, male=11), euthymic (female= 7, male=4), hypomanic (female=2, male=6), manic (female=2, male=1), mixed (female=1, male=1). 2-way ANOVA, main effect Sex: p=0.260; main effect Group: p=1.26e-07; Interaction Group x Sex: p=0.059; Tukey's HSD: control vs. depressive ***p=0.0002621, control vs. euthymic ***p=0.0008533, control vs. hypomanic ****p=0.0000470. Data are presented as violin plots with median, quartiles and data points."
NCBI gene IDs:
"miR-499-5p: 574501"