EMBO/SourceData huggingface dataset:
Figure legend: "(C-D) Immunoblotting  of EMT markers of HCC  cells treated with or without 200 nM Gboxin  for 24 hours (shTOM: shTOMM34, TOMM34  knockdown cells; OE-TOM: OE-TOMM34, TOMM34  overexpressed cells)."
NCBI gene IDs:
"TOM: 
TOM: 10953
TOMM34: 10953"
Figure legend: "(E-F) Transwell assay  showing the migration  and invasion  of HCC  cells treated with or without 200 nM Gboxin  for 36 hours (5×104 cells; shTOM: shTOMM34, TOMM34  knockdown cells). Scale bars, 100 μm. (n=3 biological replicates, two-way ANOVA). Data information: Data are presented as means ± S.D."
NCBI gene IDs:
"TOM: 10953
TOMM34: 10953"
Figure legend: "(A) B cell development in Igh∆890/∆890 mice. The relative frequencies of the indicated cell types were determined by flow cytometric  analysis of  bone marrow  cells  from  Igh∆890/∆890 and Igh+/+ mice  at the age of 3-4 weeks, indicating a 1.3-fold increase of  pro-B cells and a moderate decrease at subsequent  B cell developmental stages in  Igh∆890/∆890 mice. Statistical data are shown as mean value with SEM. Data information: Statistical data were analyzed by multiple t-tests (unpaired and two-tailed with Holm-Sidak correction; A, ; *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001, ****P &lt; 0.0001. Each dot (A, corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(B) Two-color 3D  DNA-FISH  analysis of ex vivo sorted pro-B cells of the indicated genotypes with the RP23-340K14 (red) and RP24-275L15  (green) BAC probes (Fig 1A). Representative images are show above. Dot plots (below) show the distances measured between the two DNA  signals in individual Igh alleles (2,123 for Rag2-/-, 1,514 for Igh∆890/∆890 Rag2-/- and 502 for Vav-Cre Pax5fl/fl (Pax5∆/∆) Rag2-/-pro-B cells) together with the mean distance (red bar) and SEM determined for each genotype. In total, four independent DNA-FISH experiments were performed. Data information: Statistical data were analyzed by multiple t-tests (unpaired one-way ANOVA (Tukey post-hoc test; B); *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001, ****P &lt; 0.0001."
NCBI gene IDs:
"Cre: 2777477
Igh: 111507
Pax5: 18507
Rag2: 19374
Vav: 7409"
Figure legend: "(C, VH   gene  recombination analysis in ex vivo sorted  Igh∆890/∆890 and Igh+/+ pro-B cells, as determined by VDJ-seq experiments (C) The percentages of uniquely identified DJH and VDJH sequences are shown as mean percentage with SEM. Each dot corresponds to an independent VDJ-seq experiments performed with sorted pro-B cells from one mouse. Data information: Statistical data were analyzed by multiple t-tests (unpaired and two-tailed with Holm-Sidak correction; ; *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001, ****P &lt; 0.0001. Each dot C, corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507
VH: 111507"
Figure legend: "(B) Flow cytometric determination of the ratio of immature IgMb  (B6) to IgMa   (129) B cells in the bone marrow  of Igh∆890(B6)/+(129), IghP4V (B6)/+(129) and control Igh+(B6)/+(129) mice, which were generated by crossing Igh∆890/+, IghP4V/+ and Igh+/+ mice  on the C57BL/6 (B6) background with Igh+/+ mice  of the 129/Sv (129) strain. The rearranged Igh  alleles of the C57BL/6 and 129/Sv strains give rise to the expression  of IgMb  and IgMa, respectively. The IgMb  (B6) to IgMa  (129) ratio is shown as mean value with SEM (right). Data information: Statistical data were analyzed by multiple t-tests (unpaired and two-tailed with Holm-Sidak correction; B, ; *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001, ****P &lt; 0.0001. Each dot (B, corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(C) Summary of the ratios of immature IgMb  (B6) to IgMa  (129)  B cells, determined for the indicated six mouse  strains analyzed and shown as mean values with SEM. The ratio determined for control  Igh+(B6)/+(129) B cells was set to 1. Data information: Statistical data were analyzed by multiple t-tests (unpaired one-way ANOVA (Tukey post-hoc test; C, ; *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001, ****P &lt; 0.0001. Each dot C, corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(D) Comparison of the VDJ-seq  data obtained with  pro-B cells  of the Igh+/+ (black), Igh∆890/∆890 (white bars) and IghP4V/P4V (gray) genotypes. The different VH genes (horizontal axis) are aligned according to their position in the Igh  locus The usage of each VH gene (vertical axis) is shown as percentage of all VDJH and DJH recombination  events determined for each pro-B cell  type. The relative frequency of each VH gene is shown as mean value with SEM and is based on three independent VDJ-seq experiments for  pro-B cells of each genotype."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(A) Presence of open chromatin  and the active histone marks H3K27ac and H3K4me2 at the V8.8E enhancer in  pro-B cells. The location of the VH8-8  gene, V8.8E enhancer (dashed line) and PAIR5  element are shown together with the mm9  genomic coordinates of mouse chromosome 12. The VH8-8 gene with 500 bp of its upstream and downstream sequences (indicated by violet overlay) was inserted with the Floxin method at the deletion point of the Igh∆890 allele to generate the IghV8-8  allele"
NCBI gene IDs:
"Igh: 111507
VH8-8: 780938
V8-8: 780938
mm9: 109279847"
Figure legend: "(B, Flow-cytometric analysis (B) of GFP expression  are shown for  pro-B, pre-B,  immature B  and recirculating B cells from the bone marrow of IghP4GV/P4GV (dark green, n=16), IghP4GV/+ (light green, n=12) and control Igh+/+ (black, n=13) mice."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "C) geometric mean fluorescence intensity measurements (MFI, C) of GFP expression  are shown for pro-B,  pre-B, immature B and  recirculating B cells  from the bone marrow of  IghP4GV/P4GV (dark green, n=16),  IghP4GV/+ (light green, n=12) and control  Igh+/+ (black, n=13) mice. Geometric mean fluorescence intensity measurements (C) are shown as mean values with SEM."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "G) Absence of GFP expression  in DN (CD4-CD8-) and  DP (CD4+CD8+)  T cells, geometric mean fluorescence intensity measurements (G) of GFP expression  in thymocytes  from the indicated mice. Geometric mean fluorescence intensity measurements (G) are shown as mean value with SEM based on 12 (Igh+/+), 11 (IghP4GV/+) or 12 (IghP4GV/P4GV) independent replicates."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(A, B) Flow-cytometric analysis (A) and geometric mean fluorescence intensity measurements (MFI, B) of GFP expression  are shown for pro-B, pre-B, immature B and  recirculating B cells from the bone marrow  of IghP4GV/+ (green, n=6), IghP4∆Pax5GV/+ (yellow, n=5), IghP4∆CtcfGV/+ (brown, n=4) and control Igh+/+ (black, n=4) mice. Geometric mean fluorescence intensity measurements (B) are shown as mean value with SEM. Data information: Each dot corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(C, D) Activation of the PAIR4-V8.7E  module in thymocytes  upon loss of CTCF   binding at PAIR4, as shown by flow-cytometric  analysis (C) and geometric mean fluorescence intensity measurements (MFI, D) of GFP expression  in DN, DP, CD4+  and CD8+ thymocytes of IghP4∆CtcfGV/+ (light brown, n=5) and  IghP4∆CtcfGV/P4∆CtcfGV (dark brown, n=6) mice  compared with control Igh+/+ (black, n=7) mice. Geometric mean fluorescence intensity measurements (D) are shown as mean value with SEM. Data information: Each dot corresponds to one mouse."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(B, C) Flow-cytometric  analysis (B) and geometric mean fluorescence intensity measurements (MFI, C) of YFP expression  are shown for MPPs  (LSK), LMPPs, ALPs  and BLPs  from the bone marrow  of Rosa26LSL-YPF/+ IghCμCre/+ (violet) and control  Rosa26LSL-YPF/+ Igh+/+ (black) mice. Geometric mean fluorescence intensity measurements (B) are shown as mean value with SEM and have been normalized by setting the mean value obtained with Igh+/+ cells to 1. Data information: Each dot corresponds to one mouse."
NCBI gene IDs:
"Cre: 2777477
Rosa26: 14910
Igh: 111507"
Figure legend: "Flow-cytometric  analysis (E) of GFP expression  are shown for MPPs  (LSK), LMPPs, ALPs, BLPs,  pro-B, pre-B, immature B and recirculating B cells from the bone marrow  of IghEμG/+ (light blue), IghEμG/EμG (dark blue) and control Igh+/+ (black) mice."
NCBI gene IDs:
"Igh: 111507"
Figure legend: "(F) Representative fluorescence micrographs of A549 cells of the indicated genotypes. Cells were either left untransduced (mock) or transduced with PIDD1-V5 lentiviral vectors expressing the PIDD1 non-cleavable derivative (PIDD1S446A-S588A) or truncations thereof. Blow-ups without Hoechst 33342 are magnified 2.5X. Scale bar: 5 μm."
NCBI gene IDs:
"PIDD1: 55367"
Figure legend: "(E) Movie stills of a representative RPE1 cell stably expressing CETN1-GFP treated with DHCB and subjected to time-lapse video microscopy in the presence of SiR-DNA. Time is expressed in minutes, relative to anaphase onset. The dashed line indicates the plasma membrane of the cell of interest, arrowheads indicate the centrosomes' position."
NCBI gene IDs:
"GFP: 
CETN1: 1068"
Figure legend: "(F) Centrosomal distance over time in RPE1 cells stably expressing CETN1-GFP and treated with DHCB. Time zero corresponds to the frame preceding anaphase onset. Coloured dots (lower panel) summarize the clustering time for each cell, mean ± standard deviation in black. Data calculated from four-dimensional imaging as in (E). N = 10 cells."
NCBI gene IDs:
"GFP: 
CETN1: 1068"
Figure legend: "(C) RT-qPCR analysis of PIDD1 mRNA expression in A549 cells upon treatment with increasing doses of Nutlin 3a (i.e. 3.3 μM or 10 μM) using two independent probes. The average fold of induction ± standard deviation is shown. N = 3 biological replicates with two technical replicates each. Comparisons were performed between treatments of every genotype and the corresponding treatment of wild type (WT) cells"
NCBI gene IDs:
"PIDD1: 55367"
Figure legend: "E) Representative western blot of the solubility analysis of GK variants upon overexpression in E. coli K12. Bands show Soluble (Sol) and Pellet fractions after centrifugation at 17,100 g for 15 mins. \"-DnaK\" indicates expression in E. coli K12 DnaK knockout line, \"+ Dnak\" indicates co-expression of pKJE7, encoding DnaK, DnaJ and GrpE."
NCBI gene IDs:
"DnaK: "
Figure legend: "G) Structured Illumination Microsopy (SIM) images of E. coli after three hours of expression of one of the GK variants. GFP fluorescence is shown in green. \"ΔDnaK\" indicates expression in E. coli K12 DnaK knockout line, \"+ Dnak\" indicates co-expression of pKJE7, encoding DnaK, DnaJ and GrpE."
NCBI gene IDs:
"DnaK: "
Figure legend: "Microautophagic degradation of peroxisomes is not observed in a vacuolar protease-negative strain (STK7) of P. pastoris. Kinetics of morphological changes in vacuoles and peroxisomal GFP-SKL during (a) glucose adaptation and (b) ethanol adaptation. (c) Fluorescence images taken after 2 h of glucose adaptation. Arrows show GFP-SKL in vacuolar matrix. Some cells showed diffusion of GFP-SKL into the vacuolar matrix."
NCBI gene IDs:
"vacuolar protease: 855949"
Figure legend: "(a) Visualization of alcohol oxidase activity in colonies after (a) glucose adaptation for 8 h and ethanol adaptation for 24 h in wild-type (strain PPY12) and pag mutant cells (strains STK1-STK6, Materials and Methods) of P. pastoris. (b) Western-blot analysis of samples taken from cultures shifted from methanol to glucose for the indicated time. Antibodies used were AOX, alcohol oxidase; F1, mitochondrial F1β subunit; G6PDH, glucose-6-phosphate dehydrogenase. Growth curve of the wild-type strain PPY12 and the pag4 mutant (strain STK4) after shift from methanol to glucose."
NCBI gene IDs:
"pag4: 853034"
Figure legend: "Fluorescence images of (a) pag2 (strain STK2) and (b) pag3 (strain STK3) mutants of P. pastoris after a 3 h shift to glucose. (b) Arrows show deeply invaginated structures of vacuolar membranes surrounding peroxisomes in the pag3 mutant."
NCBI gene IDs:
"pag2: 853219
pag3: 851929"
Figure legend: "Fluorescence images of the pag4 (strain STK4) mutant of P. pastoris after (a) 0, (b) 3, or (c) 6 h of glucose adaptation. The vacuolar membrane proliferated extensively and surrounded peroxisomes during glucose adaptation."
NCBI gene IDs:
"pag4: 853034"
Figure legend: "Microautophagy of peroxisomes in a pex1-ts mutant (strain SJH242) of P. pastoris expressing GFP-SKL from the constitutive glyceraldehyde-3-phosphate dehydrogenase (GAPDH) promoter at the restrictive temperature for peroxisome assembly (34°C). (a) Kinetics of peroxisome degradation at 34°C. Strain SJH242 was induced on methanol at 23°C, and glucose adaptation was performed at 34°C. (b) Changes in vacuole morphology were seen even in the absence of normal peroxisomes. At 0 h, SJH242 cells were grown at 34°C when GFP-SKL was diffuse in the cytosol and many vacuoles showed spherical morphologies. After 2 h, ∼20-30% vacuoles showed complicated membrane structures representative of stage 2 cells."
NCBI gene IDs:
"GAPDH: 
pex1: 853636"
Figure legend: "(A) In vivo fundusimage of an AAV-injected rd1mouse expressing ReaChR-mCitrine driven by the hSyn promoter (AAV2-hSyn:ReaChR-mCitrine); transduced RGCs are visible as green puncta."
NCBI gene IDs:
"rd1: 18587
hSyn: 8224///6854///6853"
Figure legend: "(A) Examples of local field potential (LFP) traces in response to light flashes at 595 nm (light stimulus is shown as orange bar; 1.25 × 1017 photons cm-2 s-1). (B) Spike raster plots in response to 200 repetitions of the same light stimulus. (C) Averaged spike responses shown as peristimulus time histograms (PSTH, bin size: 5 ms) based on the spike raster plots. Top-row: WT-mice, middle row: rd1 control mice, bottom-row: ReaChR-treated rd1 mice. (D) ReaChR-induced cortical responses (spikes and LFP) as a function of light intensity at (595 nm) demonstrating that ReaChR-treated rd1 mice (n = 4) can detect light in the visual cortex at intensities well below the safety threshold allowed for the humanretina. Data presented as mean ± SEM."
NCBI gene IDs:
"ReaChR: 
rd1: 18587"
Figure legend: "(A) Locomotory behavior of a representative rd1 and ReaChR-treated mouse during illumination with light at 590 nm in an open field arena (irradiance measured at the level of the mice's eyes was ~1015 photons cm-2 s-1, cumulative activity trajectories are shown as red traces after 2 min of illumination), see also EV Movie 1 and EV Movie 2. (B) Mean velocities of the ReaChR-treated and rd1mice analyzed over a duration of 2 min at light onset. The mean velocity of ReaChR-treated mice were significantly reduced than rd1mice (P = 0.006, one-tailed t-test) upon illumination. Mean ± SEM are shown for each group. ReaChR-treated rd1 (n = 11), rd1 (n = 12)."
NCBI gene IDs:
"ReaChR: 
rd1: 18587"
Figure legend: "(C) Light/dark box test. Percentage of time mice spent in the light compartment as a function of light intensity (WT, n = 9; rd1, n = 9; ReaChR-treated n = 7). Mean ± SEM are shown for each group. (D) Percentage of time rd1 (n = 9), WT (n = 9) and ReaChR-treated (n = 7) mice spent in the light compartment for an illumination intensity of 2.11 × 1015 photons cm-2 s-1. Both WT as well as ReaChR-treated mice spent significantly less time in the light compartment than the rd1mice (P &lt; 0.0001, ordinary one-way ANOVA). *** and **** indicates significance levels determined by Tukey's multiple comparisons test for rd1 vs. WT and rd1 vs. ReaChR-treated. See also EV Movie 3 for the response of a representative ReaChR-treated rd1 mouse plotted in (D)."
NCBI gene IDs:
"ReaChR: 
rd1: 18587"
Figure legend: "(A) Vertical section of macaqueretinal explant transfected with AAV2 hSyn:ReaChR-mCit after 10 days of incubation exhibiting mCitrine expresssion densely in neuronal processes in the GCL. (B) Vertical section of macaqueretinal explant transfected with AAV8 Y447 733F-CAG:ReaChR-GFP after 3 days of incubation. GFP expression was primarily observed in the cell bodies but also in processes of RGCs; green: endogenous GFP fluorescence; blue: DAPI; outer nuclear layer (ONL). scale bars = 10 µm."
NCBI gene IDs:
"CAG: 
hSyn: 6853///8224///6854"
Figure legend: "(A) Humanretinal explant, prepared from the far periphery, infected with an AAV8 Y447 733F-CAG :ReaChR-GFP, placed on a multi-electrode array chip (left); GFP epifluorescence of the same explant following 12 days of incubation is shown on the right. Scale bars: 100 µm. The location of two cells that responded to repeated 2 s full field stimulations of orange light (600 nm) are highlighted."
NCBI gene IDs:
"CAG: "
Figure legend: "(B) Sashimi plots comparing muscle RNA sequencing reads in P1 (red) and two control muscle samples (blue and green) at the exons 3-5 of BET1."
NCBI gene IDs:
"BET1: 10282"
Figure legend: "(D) HeLa-cells stably expressing the pC4-reporter were transfected with control siRNA (ctrl) or two independent siRNAs (#1 and #2) directed against BET1 (siRNA #1 is shown in figure EV 2B). 2d post-transfection the pC4-secretion assay was performed for 0 and 10 min post induction of secretion. Representative images are shown (upper panel ctrl and lower panel #2 siRNA, respectively. Scale bar: 20 µm. Right panels represent magnifications of dashed areas."
NCBI gene IDs:
"BET1: 10282"
Figure legend: "(A) Volcano plot of AP-MS data using HA-BET1 or Ile51Ser."
NCBI gene IDs:
"HA: 
BET1: 10282"
Figure legend: "(B) Co-IPs using HA-tagged constructs expressed in HEK293 cells. As baits HA-tagged proteins were immunoprecipitated with anti-HA beads. IP samples and cell lysates were subjected to immunoblotting with α-HA, α-ERGIC-53, α-BET1, α-SEC22b, α-GOSR2 and α-GAPDH antibodies, respectively."
NCBI gene IDs:
"HA: "
Figure legend: "Ribosome occupancy map at the LINC00665 locus. MCF10A were either mock-treated or treated with TGF-β and Ribosome profiling on three biological replicates were shown."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Relative levels of CIP2A-BP were determined by polysome profiling and qRT-PCR in MCF-10A and TNBC cells either mock treated or treated with TGF-β. Relative levels of LINC00665 were determined by qRT-PCR in MCF-10A and TNBC cells either mock treated or treated with TGF-β."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Upper: putative ORFs in LINC00665. Lower: The ORFs were constructed into pcDNA3.1 vector and transfected to MCF-10A cells for 24h. The ORFs-His fusion proteins were determined by western blot with anti-His antibody."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Diagram of the His fusion constructs. The start codon ATG of the LINC00665 ORF is mutated to ATT. The indicated constructs were stably expressed in MDA-MB-231 cells, micropeptide CIP2A-BP was immuno-stained using anti-His (I) and anti-CIP2A-BP antibodies (K) respectively; CIP2A-BP-His fusion protein levels were determined by western blotting with anti-His and CIP2A-BP antibodies"
NCBI gene IDs:
"His: 
LINC00665: 100506930"
Figure legend: "MCF-10A cells were first transfected with anti-LINC00665 translation-blocking antisense oligo, then micropeptide CIP2A-BP was detected."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Migration and invasion of TNBC cells transfected with LINC00665 ORF and control lentiviruses for 48h. Right panel is the quantification of TNBC cells that migrated through the membrane without the Matrigel (upper) and invaded through Matrigel-coated membrane (lower)."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Wound-healing assay on Hs578T and MDA-MB-231 cells transfected with LINC00665 ORF expressing and control lentiviruses. The wound edges were photographed at the indicated time points after wounding. Right panel is the quantification of the relative wound healing area."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "Chromatin immunoprecipitation showing Smad4 occupancy at the 4E-BP1 locus in TNBC cells. Co-precipitated DNA was analyzed for amplicons A-E by qPCR. Values represent the enrichment of bound protein fractions relative to input."
NCBI gene IDs:
"4E-BP1: 1978"
Figure legend: "Luciferase reporter assay was performed in Hs578T (F) and MDA-MB-231 (G) cells following co-transfection with wildtype or mutant 4E-BP1 promoter fragment and Smad4 over-expressed, or knocked down and respective controls for 36h and treatment with TGF-β for 24h. The reporter constructs were expressing the luciferase gene under 4E-BP1 promoter segment or 4E-BP1 promoter deleted 0 to +200 region."
NCBI gene IDs:
"luciferase: 
4E-BP1: 1978
Smad4: 4089"
Figure legend: "Smad4 siRNA and corresponding control transfected TNBC cells were cultured with or without TGF-β. The indicated proteins were determined by Immunoblotting analysis."
NCBI gene IDs:
"Smad4: 4089"
Figure legend: "4E-BP1 siRNA and corresponding control transfected TNBC cells were cultured with or without TGF-β. The indicated proteins were determined by immunoblotting analysis."
NCBI gene IDs:
"4E-BP1: 1978"
Figure legend: "LINC00665 ORF-His plasmid was transfected into MDA-MB-231 cells. Whole-cell lysates were subjected to co-immunoprecipitation using anti-His antibody and immunoblot analysis with CIP2A antibody to verify that CIP2A bound to CIP2A-BP."
NCBI gene IDs:
"His: 
LINC00665: 100506930"
Figure legend: "LINC00665 ORF-His plasmid was transfected into MDA-MB-231 cells. Whole-cell lysates were subjected to co-immunoprecipitation by CIP2A antibody and immunoblot analysis with CIP2A-BP antibodies to verify that CIP2A-BP bound to CIP2A."
NCBI gene IDs:
"His: 
LINC00665: 100506930"
Figure legend: "LINC00665 ORF-His plasmid was transfected into MDA-MB-231 cells. Whole-cell lysates were treated with 30 mg/mL RNase A for 30 min, the indicated complexes were co-immunoprecipitated by anti-His or anti-CIP2A antibody, and CIP2A or micropeptide CIP2A-BP were detected."
NCBI gene IDs:
"His: 
LINC00665: 100506930"
Figure legend: "The expression levels of the indicated proteins were detected by immunoblotting analysis in CIP2A-BP KO, LINC00665 ORF overexpressed (OE) and respective controls of TNBC cells."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "PP2A activity was measured using a protein phosphatase assay kit. PP2A activity assay was performed to evaluate PP2A activity in CIP2A-BP KO, LINC00665 ORF overexpressed (OE) and respective control TNBC cells."
NCBI gene IDs:
"LINC00665: 100506930"
Figure legend: "MDA-MB-231 cells were transfected with anti-CIP2A siRNAs. Whole-cell lysates of these cells were subjected to immunoblot analysis with CIP2A, CIP2A-BP, PP2Ac, p-AKT, AKT and β-actin antibodies."
NCBI gene IDs:
"CIP2A: 57650"
Figure legend: "CIP2A-BP KO, LINC00665 ORF overexpressed (OE) and respective control MDA-MB-231 cells were transfected with anti-CIP2A siRNAs. PP2A activity assay was performed to evaluate PP2A activity in the indicated cells."
NCBI gene IDs:
"CIP2A: 57650
LINC00665: 100506930"
Figure legend: "Macroscopic and histological analysis of the lungs of 140 days old MMTV-PyMT mice; lung metastatic nodules were visualized 8 weeks post-transplantation (5 mice per group). Right panel is the quantification of pulmonary metastases."
NCBI gene IDs:
"PyMT: "
Figure legend: "Immunohistochemistry (IHC) staining of p-AKT of mammary tumors from MMTV-PyMT;CIP2A-BP+/+ or MMTV-PyMT;CIP2A-BP-/- mice. Lower panels show higher-magnification images of insets in upper panels. Right panel is the quantification of IHC staining p-AKT ."
NCBI gene IDs:
"PyMT: "
Figure legend: "MMTV-PyMT mice were injected with CIP2A-BP or svCIP2A-BP via mammary fat pad. Macroscopic and histological analysis of the lungs of 140 days old MMTV-PyMT mice; lung metastatic nodules were visualized 8 weeks post-transplantation (5 mice per group). Right panel is the quantification of pulmonary metastases."
NCBI gene IDs:
"PyMT: "
Figure legend: "Representative IHC images of p-AKT of mammary tumors from MMTV-PyMT mice that were injected with CIP2A-BP or svCIP2A-BP via mammary fat pad; Lower panels show higher-magnification images of insets in upper panels. Right panel is the quantification of IHC staining p-AKT."
NCBI gene IDs:
"PyMT: "