EMBO/SourceData huggingface dataset:
Figure legend: "(L) The average number of GSC and CB in nos-Gal4 line, nos-Gal4&gt;UAS-eggpl-RNAi line and nos-Gal4&gt;UAS-eggpl::GFP line on 2 day, 7 day, 14 day and 21 day. Error bars show mean ± SEM, one-way ANOVA, ns indicates no significant difference, *P&lt;0.05, ***P&lt;0.001, n ≥ 72, biological replicates."
NCBI gene IDs:
"GFP: 
eggpl: 318223
Gal4: 855828
nos: 42297"
Figure legend: "(Q) The statistical analysis of the average number of GSCs and CBs and Cysts in eggpl[1] line. Error bars show mean ± SEM, one-way ANOVA, ns indicates no significant difference, ***P&lt;0.001, n ≥ 104, biological replicates."
NCBI gene IDs:
"eggpl: 318223"
Figure legend: "(R) The average number of apoptotic germ cells in wild type, nos-Gal4&gt;UAS-eggpl-RNAi line and eggpl[1] line. Error bars show mean ± SEM, one-way ANOVA, ns indicates no significant difference (biological replicates, n=3), and N represents the total number of counted ovarioles."
NCBI gene IDs:
"eggpl: 318223
Gal4: 855828
nos: 42297"
Figure legend: "(D) Immunofluorescence staining on PGCs of larvae testis tissue. The scale bar is 20 μm. (E) Immunofluorescence staining with anti-α-Spectrin (red) and anti-Vasa (green) on testis from wild type or eggpl[1] flies. The scale bar is 10 μm."
NCBI gene IDs:
"eggpl: 318223"
Figure legend: "(B) The oviposition of wild type, Nos-Gal4&gt;UAS-eggpl-RNAi and eggpl[1] line over 21 days. Error bars show mean ± SEM, 3 biological replicates (n=3) were performed, and there were 10 female and 5 male adult flies in each biological replicate."
NCBI gene IDs:
"eggpl: 318223
Gal4: 855828
Nos: 42297"
Figure legend: "(F) Immunofluorescence staining with anti-GFP on germaria from eggpl::GFP knock-in flies with or without feeding fresh yeast paste on day 2-, 7-, 14- and 21. The dotted line indicates the examined area. The scale bar is 10 μm. (G) Quantification of the GFP intensity mean in the eggpl::GFP knock-in line. The central band indicates the median, the box length indicates the interquartile range, and the upper and whisker indicate the maximum and minimum value respectively. The 10 biological replicates (n=10) were performed, one-way ANOVA, ***P&lt;0.001. The dashed line indicates the examined area."
NCBI gene IDs:
"GFP: 
eggpl: 318223"
Figure legend: "(B) Quantification of the GFP signal in germaria from eggpl::GFP knock-in flies of the indicated genotypes under different conditions. The central band indicates the median, the box length indicates the interquartile range, and the upper and whisker indicate the maximum and minimum value respectively, one-way ANOVA, **P&lt;0.01, ***P&lt;0.001, n = 10, biological replicates."
NCBI gene IDs:
"GFP: 
eggpl: 318223"
Figure legend: "(b-e) Normalized ratio between luciferase activity bound to beads and present in lysates. The indicated purified GST fusion proteins coupled to beads were incubated with lysates of 293ET cells expressing Nap1, Sintbad or Tank, each fused to luciferase (b)"
NCBI gene IDs:
"luciferase: 
Nap1: 64343
Tank: 10010
Sintbad: 9755"
Figure legend: "(c), lysates of 293ET cells expressing the indicated Nap1 mutants fused to luciferase"
NCBI gene IDs:
"luciferase: 
Nap1: 64343"
Figure legend: "(d), lysates of E. coli expressing Nap1(1-85) fused to luciferase"
NCBI gene IDs:
"luciferase: 
Nap1: 64343"
Figure legend: "(e) lysates of 293ET cells expressing Nap1, NEMO or Optineurin fused to luciferase"
NCBI gene IDs:
"luciferase: 
Nap1: 64343
NEMO: 8517
Optineurin: 10133"
Figure legend: "(c,d) Normalized ratio between luciferase activity bound to beads and present in lysates. The indicated purified GST fusion proteins coupled to beads were incubated with bacterially expressed Nap1(1-85) fused to luciferase. Reactions were complemented with lysates from 293ET cells that had been depleted with the indicated (α-) antibodies (c, top). Immunoblot of lysates after depletion (c, bottom)."
NCBI gene IDs:
"luciferase: 
Nap1: 64343"
Figure legend: "(c,d) Normalized ratio between luciferase activity bound to beads and present in lysates. The indicated purified GST fusion proteins coupled to beads were incubated with bacterially expressed Nap1(1-85) fused to luciferase.Reactions were complemented with the indicated amounts of lysates from E. coli cultures expressing myelin basic protein (MBP) fused to NDP52 (d)."
NCBI gene IDs:
"luciferase: 
Nap1: 64343"
Figure legend: "Percentage of NDP52-positive S. Typhimurium among ubiquitin-coated bacteria, determined by microscopy. HeLa cells transduced with the indicated NDP52 domain-deletion mutants fused to green fluorescent protein were infected with S. Typhimurium and stained for ubiquitin 2 h after infection. ZnF, zinc finger domain. *P 0.01, Student's t-test. Mean and s.d. of triplicate coverslips from two independent experiments; more than 50 ubiquitin-positive bacteria were evaluated per coverslip."
NCBI gene IDs:
"NDP52: 10241"
Figure legend: "(a) Lysates of cells transfected with the indicated siRNAs blotted for NDP52, TBK1, IKKε and proliferating cell nuclear antigen (PCNA). Control, a nonspecific band detected by the IKKε antibody."
NCBI gene IDs:
"IKKε: 9641"
Figure legend: "(a-d) Analysis of HeLa cells stably expressing green fluorescent protein-LC3, infected with S. Typhimurium. (a) Confocal micrographs of cells stained 1 h after infection with NDP52 antiserum. Scale bar, 10 μm; arrowheads, bacteria shown in insets. (b) Colocalization of NDP52 with LC3-positive bacteria. (c,d) Counts of LC3-positive S. Typhimurium 1 h after infection in cells transfected with the indicated siRNAs. In c, cells were stained for ubiquitin (Ub); in d, red fluorescence protein (RFP)-expressing S. Typhimurium were used. Means of duplicate counts from four independent experiments; *P 0.05, Student's t-test."
NCBI gene IDs:
"NDP52: 10241
LC3: 440738///81631///84557"
Figure legend: "(f) Normalized ratio of luciferase-LC3 binding to beads. The indicated purified GST proteins coupled to beads were incubated with bacterially expressed LC3 fused to luciferase and the indicated volumes of lysed E. coli expressing NDP52. Data in a,b,e and f are representative of at least two independent experiments."
NCBI gene IDs:
"luciferase: 
LC3: 81631///84557///440738"
Figure legend: "Logarithm of the relative viability  after treatment with Resiquimod  (A, n=169), IL4  (B, n=174) stratified by   trisomy 12, and in A, also by IGHV  status. P-values from Student's t-test (two-sided, non-paired). The central bar, boxes and whiskers of the plot represent the median, first and third quartiles, and 1.5-times IQR, respectively."
NCBI gene IDs:
"IGHV: 3492"
Figure legend: "Beeswarm-boxplots of the natural logarithm of the relative viability  of 169 CLL  samples, for (C) fludarabine  + CpG ODN and combinatorial treatments, faceted by IGHV  status and trisomy 12 status. P-values from paired Student's t-test . The central bar, boxes and whiskers of the plot represent the median, first and third quartiles, and 1.5-times IQR, respectively."
NCBI gene IDs:
"IGHV: 3492"
Figure legend: "Beeswarm-boxplots of the natural logarithm of the relative viability  of 169 CLL  samples, for (D) ibrutinib  + IL4  single and combinatorial treatments, faceted by IGHV  status and trisomy 12 status. P-values from paired Student's t-test . The central bar, boxes and whiskers of the plot represent the median, first and third quartiles, and 1.5-times IQR, respectively."
NCBI gene IDs:
"IGHV: 3492"
Figure legend: "(C) Gene expression for Stat3, Klf2, Esrrb and Tfcp2l1 during EpiSC resetting relative to established mouse ESCs. β-actin serves as an internal control. Mean +/- SEM, n=4 independent experiments. * = p&lt;0.05 Student&quot;s t"
NCBI gene IDs:
"Esrrb: 26380
Klf2: 16598
Stat3: 20848
Tfcp2l1: 81879"
Figure legend: "(C) Left: Flow cytometry profiles of the resetting progression of EpiSCs stably transfected with the Esrrb-T2A-Klf4 construct and cultured in 2i+LIF with DOX for 2 and 4 days, with the indicated fraction of cells sorted for colony formation assay. Since the Venus reporter is under the control of a DOX responsive element, and the emission spectra of Venus and GFP fluorescence overlap, Oct4-GFP reporter could not be fully distinguished from Venus expression. Right: Number of AP+ colonies formed from 250 sorted cells from indicated fractions. Data points represent two technical replicates of one out of two independent experiments"
NCBI gene IDs:
"Esrrb: 26380
Klf4: 16600"
Figure legend: "(C) Left, resetting capacity of Klf2 and Klf4 KO EpiSCs measured by Oct4-GFP+ colony formation at Day 6 of resetting. Data points represent two independent experiments. Right, representative fluorescent and bright field images of wild type and Klf2 KO EpiSCs at Day 6 of resetting in 2i+LIF"
NCBI gene IDs:
"Klf2: 16598
Klf4: 16600"
Figure legend: "(D) Expression of naïve pluripotency, transition and somatic lineage markers in wild type and Klf2 KO EpiSCs during a resetting time course in 2i+LIF. Expression is normalised to wild type EpiSCs in A/F, and β-actin was used as internal control. The values shown correspond to the average expression of three technical replicates from one representative experiment out of two"
NCBI gene IDs:
"β-actin: 
Klf2: 16598"
Figure legend: "(E) Rescue of Klf2 KO EpiSC resetting by forced expression of individual network components measured by Oct4-GFP+ colony formation at Day 6 of resetting in 2i+LIF. Data points represent two independent experiments"
NCBI gene IDs:
"Klf2: 16598"
Figure legend: "(G) EpiSC resetting in 2i+LIF measured by Oct4-GFP+ colony formation after Stat3 siRNA in wild type EpiSCs (left), or Klf4 KO EpiSCs transfected with Tfcp2l1 and Gbx2 siRNAs. n=3 independent experiments in wild type cells (box plots indicate min, median, max), n=2 for Klf4-/- cells (box plots indicate min, mean, max)"
NCBI gene IDs:
"Gbx2: 14472
Klf4: 16600
Stat3: 20848
Tfcp2l1: 81879"
Figure legend: "(H) EpiSC resetting in 2i+LIF measured by Oct4-GFP+ colony formation of Stat3 knockdown EpiSCs transiently transfected with Tfcp2l1, Gbx2 and Klf4. n=4 independent experiments: Student\"s t-test, p-value indicated on plot. Box plots indicate min, median, max. See also Appendix Fi"
NCBI gene IDs:
"Gbx2: 14472
Klf4: 16600
Stat3: 20848
Tfcp2l1: 81879"
Figure legend: "(B) Comparison of predictions (left) and experimental outcome (right) for the potency of additional network factors in OSKM-driven MEF reprogramming in LIF containing medium n=4 independent experiments, except Klf2 and Nanog where n=2 independent experiments. * = p&lt;0.05 Student\"s t-test. n.s. = not significant. Red dashed lines indicate empty vector + OSKM (C) Comparison of predictions (left) and experimental outcome (right) for the potency of additional network factors in OSKM-driven MEF reprogramming in 2i+LIF. n=4 independent experiments, except Klf2 and Nanog where n=2 independent experiments. * = p&lt;0.05 Student\"s t-test. n.s. = not significant. Empty vector + OSKM reprogramming in LIF ('control no 2i') was included as a control for the effect of 2i addition. Red dashed lines indicate empty vector + OSKM control level. Box plots indicate min, median"
NCBI gene IDs:
"Klf2: 16598
Nanog: 71950"
Figure legend: "(D) Recapitulation of the gene activation kinetics during MEF reprogramming. Top, the number of regulation steps required for permanent activation of the indicated gene. Tfcp2l1 and Sall4 are found to activate earlier than Nanog and Esrrb. Bottom, gene expression measured from sorted populations of reprogramming intermediates from O&quot;Malley et al. ("
NCBI gene IDs:
"Esrrb: 26380
Nanog: 71950
Sall4: 99377
Tfcp2l1: 81879"
Figure legend: "Quantitation of resection activity in NBS1∆N cells complemented with wild type (WT) or NBS1 R28A K160M mutant and either mock depleted (siCtrl) or depleted of CtIP (siCtIP). At least 300 cells were assessed per condition. The horizontal line represents a median, the box spans from 25th to 75th percentile and the whiskers from 10th to 90th percentile. Statistical significance was determined using ordinary one-way ANOVA with Tukey's multiple comparison test, **** (p&lt;0.0001)."
NCBI gene IDs:
"NBS1: 4683
CtIP: 5932"
Figure legend: "A. Left: Snapshots of actin  comet tails  assembled in Assembly  conditions: 4.5 µm polystyrene  beads coated with 400 nM Strep-SNAP-WA; 3 µM actin, 6 µM profilin, 90 nM Arp2/3 complex, 15 nM capping protein. Right: Tracking of the comet shown in the snapshots. Time  is encoded in color. B. Left: Snapshots of actin  comet tails  assembled in Disassembly conditions: same as assembly  conditions with 200 nM ADF/cofilin  added. Right: Tracking of the comet  shown in the snapshots. Time  is encoded in color. C. Left: Snapshots of actin  comet tails assembled in Recycling  conditions: Disassembly  conditions with 400 nM Cyclase Associated Protein (CAP) added. Right: Tracking of the comet  shown in the snapshots. Time  is encoded in color."
NCBI gene IDs:
"SNAP: "
Figure legend: "(A) Mouse embryos were immunostained with anti-neurofilament antibody (blue), showing mesencephalic projection. Dispersed axon projections (arrows point to the area of the superior colliculus) and decreased axon fibers (arrowheads point to the area of the pretectal commissure) were observed in Plcg1f/f;Nes-Cre mice at E11.5 (n = 20). The areas of the superior colliculus is shown magnified in each inset (scale bar = 200 μm)"
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(E) Whole-mount immunostaining images show neurofilament (red), netrin-1 (purple), and DCC (green), respectively. An E11.5 Plcg1f/f;Nes-Cre embryo showed shortened dorsal ramus and opthalmic nerves (white and yellow boxes). Scale bar: 200 μm"
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(B) Phosphorylation of PLCγ1 on Y783 was decreased after knockdown of the DCC receptor by siRNA (siDcc) (N = 3)"
NCBI gene IDs:
"Dcc: 13176
DCC receptor: 13176"
Figure legend: "(C) Western blot for the NTN1 secretion test. Lane #1: transfection-free lysate, #2: transfection-free supernatant, #3: NTN1-transfected cell lyasate, #3 and #4: NTN-1- transfected supernatant"
NCBI gene IDs:
"NTN-1: 9423
NTN1: 9423"
Figure legend: "(D) Ventral mesencephalic (A9) cultures (daggers) derived from control or Plcg1f/f;Nes-Cre mice, were co-cultured with netrin-1-releasing 293T cell aggregates (asterisks; scale bar = 100 μm). The areas delineated by the white boxes between the mesencephalon tissue and 293T cell aggregates are magnified in the respective insets (n = 4)"
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(I) Primary mesencephalic neuron culture in the absence or presence of NTN1-conditioned media (n = 100; scale bar: 500μm)"
NCBI gene IDs:
"NTN1: 9423"
Figure legend: "(H) Representative immunoblot of cultured Plcg1f/f (n = 2, N = 3) and Plcg1f/f;Nes-Cre (n = 2, N = 3) mesencephalic neurons stimulated with conditioned media containing Netrin-1."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(B) Immunohistochemical staining of control and Plcg1 conditional knockout (cKO) sagittal brain sections. The deletion of Plcg1 caused structural changes in SI and OT projections in the Plcg1f/f;Nes-Cre (d) mice compared to the controls (a) (n = 4; scale bar = 1 mm). The areas delineated by the white boxes (insets) are magnified images of the OT (b and e), and the yellow boxes are magnified images of the SI (c and f). (C) Quantification of the axon bundle distribution. Green boxes in (b) and (e) were selected as tegions of interest (ROIs) using the ZEN software (n = 4) (one-way ANOVA, F-value: 118.5745, P**&lt;0.005)."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(F) In situ hybridization of PLCγ1 in mDA neurons (scale bar = 50 μm) (green: TH, violet: DIG-labeled probe)."
NCBI gene IDs:
"PLCγ1: 18803"
Figure legend: "(G) Representative images of the CC axon bundles in control (left) and a Plcg1f/f;Nes-Cre (right) mice (n = 4). The tip of the CC was triangular in the control mouse, but oval in the Plcg1f/f;Nes-Cre mouse. The areas delineated by the white boxes are magnified in the insets (red: neurofilament, green: glial fibrillary acidic protein, blue: Hoechst; scale bar = 1 mm)."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(H) The area of the CC in the Plcg1f/f;Nes-Cre mouse was 36% smaller than that in the control mouse (scale bar = 500 μm) (I) Quantitative comparison of the CC areas in the control and Plcg1f/f;Nes-Cre mice (n = 4; t-test; **p &lt; 0.005). Data are presented as the mean ± s.e.m."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(A) Cumulative histograms based on fractional anisotropy (FA) values. (B), show the CC volume relative to FA values. As FA values increased, the structural (CC volume differences increased between the control and Plcg1f/f;Nes-Cre mice. (n = 4; Shapiro-Wilk and t-test; *p &lt; 0.05). Data are presented as the mean ± s.e.m."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(C), Cumulative histograms based on fractional anisotropy (FA) values. (D), show the number of tensors relative to FA values. As FA values increased, the structural number of tensors) differences increased between the control and Plcg1f/f;Nes-Cre mice. (n = 4; Shapiro-Wilk and t-test; *p &lt; 0.05). Data are presented as the mean ± s.e.m."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "(E) Cumulative histograms based on fractional anisotropy (FA) values. (F) show the CC volume and the number of tensors relative to FA values. As FA values increased, the structural (CC volume and the number of tensors) differences increased between the control and Plcg1f/f;Nes-Cre mice. Depending on the number of tensors, the length in the CC appeared to be shortened (E, F). (n = 4; Shapiro-Wilk and t-test; *p &lt; 0.05). Data are presented as the mean ± s.e.m."
NCBI gene IDs:
"Cre: 2777477
Nes: 18008
Plcg1: 18803"
Figure legend: "E-G, RT-qPCR measurement of mRNA for (E), Fxr1, (F), Fxr2, (G), Fmr1 during upscaling. n=4 in each condition, Student's T-test *p&lt;0.05."
NCBI gene IDs:
"Fmr1: 14265
Fxr1: 14359
Fxr2: 23879"
Figure legend: "B, Western blot analysis of total GluA1 expression in Ctrl or Fxr1 overexpression (Fxr1) condition during upscaling (Ctrl/Veh n=5, Ctrl/TTX n=5, Fxr1/Veh n=6, Fxr1/Veh n=6). One way Anova with Dunnett's Multiple Comparison Test ***p&lt;0.001."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "C, Western blot analysis of total GluA1 expression in Ctrl or Fxr1over condition during downscaling (Ctrl/Veh n=4, Ctrl/TTX n=4, Fxr1/Veh n=4, Fxr1/Veh n=4)."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "D, RT-qPCR measurement of Gria1 mRNA in Ctrl or Fxr1over condition during upscaling (Ctrl/Veh n=3, Ctrl/TTX n=3, Fxr1/Veh n=3, Fxr1/Veh n=3). One way Anova with Bonferroni's Multiple Comparison Test ***p&lt;0.001."
NCBI gene IDs:
"Fxr1: 14359
Gria1: 14799"
Figure legend: "F, Measurement of relative luciferase signal after co-transfection of different tagged luciferase constructs along with GFP (Ctrl) or GFP-Fxr1 (Fxr1) plasmids. n=5 in each condition, Student's T-test *p&lt;0.05, ***p&lt;0.001."
NCBI gene IDs:
"GFP: 
luciferase: 
Fxr1: 14359"
Figure legend: "G, Immunostaining for surface GluA1 in GFP (Ctrl) or GFP-Fxr1 (Fxr1 over) infected cultures after treatment with Veh, TTX or BIC for 48h."
NCBI gene IDs:
"GFP: 
Fxr1: 14359"
Figure legend: "Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from cultured cortical neurons after 48 hours of 1 µM TTX or Veh exposure (E) Fxr1overexpressing neurons (Fxr1/Veh n=10 and Fxr1/TTX n=8)"
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from cultured cortical neurons after 48 hours of 1 µM TTX or Veh exposure (F) Gsk3 KO neurons (Gsk3KO/Veh n=10 and Gsk3KO/TTX n=11)"
NCBI gene IDs:
"Gsk3: 56637"
Figure legend: "Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from cultured cortical neurons after 48 hours of 1 µM TTX or Veh exposure (G) Fxr1 KO neurons (Fxr1KO/Veh n=16 and Fxr1KO/TTX n=8). H, A linear fit of Fxr1 KO/Veh and Ctrl/Veh amplitudes. I, The degrees of overlap between Fxr1 KO/Veh and Ctrl/Veh data were assessed using various scaling factors. The largest non-significant p-value was obtained with 1.27 scaling factor. J, Cumulative probability plots of the mEPSCs amplitude of Ctrl/Veh, Fxr1 KO/Veh and Fxr1 KO/Veh divided by scaling factor 1.27, which yielded the maximum overlap with Ctrl/Veh data. "
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "K, Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from cultured cortical Gsk3 and Fxr1 KO neurons after 48 hours of 1 µM TTX or Veh exposure (Gsk3/Fxr1KO/Veh n=8 and Gsk3/Fxr1KO/TTX n=11). L, A linear fit of Gsk3/Fxr1 KO/Veh and Ctrl/Veh amplitudes. M, The degrees of overlap between Gsk3/Fxr1 KO/Veh and Ctrl/Veh data were assessed using various scaling factors. The largest non-significant p-value was obtained with 1.68 scaling factor. N, Cumulative probability plots of the mEPSCs amplitude of Ctrl/Veh, Gsk3/Fxr1 KO/Veh and Gsk3/Fxr1 KO/Veh divided by scaling factor 1.68, which yielded the maximum overlap with Ctrl/Veh data. "
NCBI gene IDs:
"Fxr1: 14359
Gsk3: 56637"
Figure legend: "A, Hourly distribution of wakefulness (WAKE), slow-wave sleep (SWS) and paradoxical sleep (PS) during a 24-h baseline (BL) recording and a second 24-h starting with 6-h sleep deprivation (SD) (recovery: REC) in Ctrl and Fxr1 overexpressing (Fxr1) mice. Significant Group-by-Hour interactions were found for wakefulness during BL (F23,230 = 1.67, p = 0.046) and REC (F23,230 = 2.83, p = 0.0029), for SWS during BL (F23,230 = 1.66, p = 0.045) and REC (F23,230 = 2.89, p=0.0028), and for PS during REC (F16,160 = 2.54, p=0.0018, Two-way ANOVA Huynh-Feldt corrected, *p&lt;0.05)."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "B, Power spectra for WAKE, SWS, and PS in Ctrl and Fxr1 mice computed between 0.75 and 50 Hz per 0.25-Hz for the full 24-h of BL and REC."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "C, D, The spectral activity of Fxr1 mice expressed relative to that of Ctrl mice for WAKE, SWS and PS during (C) the 24-h BL and (D) the 24-h REC. A significant difference between groups was found for the frequency band 8 to 11.75 Hz during wakefulness (t = 2.30, p=0.044 Student's T-test *p&lt;0.05)."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "E, Time course of wakefulness spectral activity ratio between low alpha (8.5-10.5 Hz) and low theta (4-6 Hz) during BL and REC in Ctrl and Fxr1 mice. A significant Group-by-Interval interaction was found for REC (F22,220 = 1.96, Two-way ANOVA Huynh-Feldt corrected; *p &lt; 0.05), and also when using BL and REC intervals of the light periods (F16,160 = 3.11, p &lt; 0.01),."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "F, Time course of SWS relative delta activity during BL and REC in Ctrl and Fxr1 mice. A significant Group-by-Interval interaction was found during REC (F13,130 = 1.89, Two-way ANOVA Huynh-Feldt corrected; *p &lt; 0.05)."
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "F-H, RNAseq measurement of mRNA for (F) Fxr1, (G) Fxr2, (H) Fmr1 during SD. n=3 in each condition, Student's T-test *p&lt;0.05."
NCBI gene IDs:
"Fmr1: 14265
Fxr1: 14359
Fxr2: 23879"
Figure legend: "Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from brain slices of S and SD mice. (C) Fxr1 overexpressing (Fxr1/S n=7 cells/5 mice, Fxr1 over/SD n=9 cells/5 mice)"
NCBI gene IDs:
"Fxr1: 14359"
Figure legend: "Cumulative probability plots of mEPSCs amplitude (500 events per cell) and representative examples of mEPSCs (left panel) recorded from brain slices of S and SD mice. (D) Gsk3 sKO (Gsk3sKO/S n=6 cells/3 mice, Gsk3sKO/SD n=7 cells/4 mice)."
NCBI gene IDs:
"Gsk3: 56637"