EMBO/SourceData huggingface dataset:
Figure legend: "B | hFwe-Lose expression is elevated in nasopharyngeal swab probes from patients with comorbidities. Box plots illustrate an increased relative expression of hFwe-Lose in nasopharyngeal swabs of patients with diabetes (n = 129), COPD (n = 20), obesity (BMI &gt; 30; n = 152), cardiomyopathy (&quot;CM&quot;, n = 19), heart failure (&quot;HF&quot;, n = 35), hypertension (&quot;HT&quot;, n = 121), chronic kidney disease (&quot;CKD&quot;, n = 60) versus disease-free patients (n = 96). Two-sided Student's t-tests were performed (compared to disease-free patients), and p-values are presented on the plot. The vertical axis represents relative hFwe-Lose expression normalized to the mean of non-hospitalized patients. The color refers to the COVID-19 disease outcome: gray for not hospitalised, blue for hospitalised and red for deceased patients. The shape of data points reflects the cohorts: circles for the training cohort (n = 203) and triangles for the validation cohort (n = 80). The central band shows the median, the box indicates the interquartile range, the whiskers extend to the most extreme points within the 1.5-fold distance of the interquartile range above and below the box."
NCBI gene IDs:
"hFwe-Lose: "
Figure legend: "D | Elevated hFwe-Lose expression in the nasal swab samples associates with patients' condition severity and respective medical treatment. Box plots illustrate an increased expression of hFwe-Lose in nasal swabs of patients, who were hospitalized within 14 days of disease progression (n = 177), admitted to intensive care unit (ICU) (n = 34), underwent intubation (n = 58), had respiratory rate greater than 30 (GT30) (n = 76), had blood oxygenation level (SpO2) less than 94% (n = 147), and who died within 30 days of disease progression (n = 21) versus patients without respective conditions. Pairwise two-sided Student's t-tests were performed (compared to patients without respective conditions), and p-values are presented on the plot. The vertical axis represents hFwe-Lose expression normalized to the mean of non-hospitalized patients. The color refers to the COVID-19 disease outcome: gray for not hospitalised, blue for hospitalised and red for deceased patients. The shape of data points reflects the cohorts: circles for the training cohort (n = 203) and triangles for the validation cohort (n = 80). The central band shows the median, the box indicates the interquartile range, the whiskers extend to the most extreme points within the 1.5-fold distance of the interquartile range above and below the box."
NCBI gene IDs:
"hFwe-Lose: "
Figure legend: "E |Elevated hFwe-Lose expression in nasal swab associates with patients' disease outcome. Box plot emphasizes an increased expression of hFwe-Lose in nasal swabs of patients, who were hospitalized within 14 days of disease progression (n = 177), and who died within 30 days of disease progression (n = 21) versus patients without respective conditions. Two-sided Student's t-tests were performed (compared to non-hospitalised patients), and p-values are presented on the plot. The vertical axis represents hFwe-Lose expression normalized to the mean of non-hospitalized patients. The color refers to the COVID-19 disease outcome: gray for not hospitalised, blue for hospitalised and red for deceased patients. The shape of data points reflects the cohorts: circles for the training cohort (n = 203) and triangles for the validation cohort (n = 80). The central band shows the median, the box indicates the interquartile range, the whiskers extend to the most extreme points within the 1.5-fold distance of the interquartile range above and below the box."
NCBI gene IDs:
"hFwe-Lose: "
Figure legend: "(A-D)  Chip-seq  genome track of ASCL1/NEUROD1, RNAPII, and H3K27Ac on ASCL1, BCL2; INSM1  and MYB (hg19), in untreated (dark blue) and in lurbinectedin treated (green) conditions respectively; to be noticed the location of CGG rich motifs (lower part of each panel) which parallel the presence of lurbinectedin (red)."
NCBI gene IDs:
"ASCL1: 429
BCL2: 596
INSM1: 3642
MYB: 4602"
Figure legend: "(A) LncRNA CRNDE expression level was measured by qRT-PCR  in cancerous  tissues  and adjacent normal tissues obtained from 35 cases of gastric cancer  (GC) patients. Data information: Data are expressed as mean ± SD. Student's t-test **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "(C) LncRNA CRNDE expression level was measured by qRT-PCR in adjacent normal tissue-derived  macrophages (NTMs) and tumor-associated macrophages (TAMs) obtained from 7 cases of GC patients. Data information: Data are expressed as mean ± SD. Student's t-test **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "(C) and (D) Left: representative  electron micrograph of exosomes  isolated from the medium of BMDMs,  BMDM-polarized  M2 macrophages, monocytes and  monocyte-polarized  M2 macrophages are depicted, showing the typical morphology  of exosomes. Upper right: the protein levels of CD63  and CD81  were measured by Western blot. Lower left: Nanoparticle tracking analysis showed that most of the particles had a similar size of 50-150 nm in diameter with a peak at around 100 nm. Lower right: LncRNA CRNDE expression levels in different exosomes. Data information: Scale bar= 100 nm. The results shown are from three biological replicates. Data are expressed as mean ± SD. Student's t-test. **P&lt;0.01 vs. BMDMs or monocytes  or BMDMs-exo or monocytes-exo. "
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "(B)  BMDM-polarized M2 macrophages  were transfected with Cy3-labelled CRNDE and  exosomes were isolated from the medium (Cy3-CRNDE-EXO). Then, MFC  cells were incubated with Cy3-CRNDE-EXO. Left: Confocal microscopy was used to detect the  Cy3-labelled  CRNDE in MFC cells. The  nuclei were  stained  with DAPI. Scale bar= 20 µm. Right: Flow cytometry was performed to quantitate the Cy3-positive cells. **P&lt;0.01 vs. MFC cells incubated with the control  EXO. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. Student's t-test."
NCBI gene IDs:
"CRNDE: "
Figure legend: "(D) Monocyte-polarized  M2 macrophages were transfected with Cy3-labelled  CRNDE  and  exosomes  were isolated from the medium (Cy3-CRNDE-EXO). Then, SGC7901 cells were incubated with  Cy3-CRNDE-EXO. Confocal microscopy  was used to detect the  Cy3-labelled CRNDE in SGC7901 cells. The  nuclei were stained  with DAPI. Scale bar= 20 µm. Right: Flow cytometry was performed to quantitate the Cy3-positive cells. **P&lt;0.01 vs. SGC7901 cells incubated with the control  EXO. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. Student's t-test."
NCBI gene IDs:
"CRNDE: "
Figure legend: "(E) SGC7901  cells were incubated with chlorpromazine (CPZ, 50 μM),  genistein (GEN, 200 μM), 5-(n-ethyl-n-isopropyl)-amiloride (EIPA, 100 μM), or methyl-β-cyclodextrin (MβCD, 10 mM), following by the incubation of Cy3-CRNDE-EXO.  Confocal microscopy was used to detect the  Cy3-labelled  CRNDE in SGC7901  cells. The nuclei were stained with  DAPI. Right: Flow cytometry was performed to quantitate the Cy3-positive cells. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. one-way ANOVA."
NCBI gene IDs:
"CRNDE: "
Figure legend: "(F) SGC7901 cells were incubated with 0, 25, 50, 100 μM CPZ, following by the incubation of  Cy3-CRNDE-EXO.  Confocal microscopy was used to detect the Cy3-labelled  CRNDE  in SGC7901 cells. The nuclei were  stained with DAPI. Right: Flow cytometry  was performed to quantitate the Cy3-positive cells. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. one-way ANOVA."
NCBI gene IDs:
"CRNDE: "
Figure legend: "Exosomes were isolated from the media of  BMDMs  (BMDMs-exo), BMDM-polarized M2 macrophages  (M2-exo), BMDM-polarized  M2 macrophages transfected with si-CRNDE (M2-si-CRNDE-exo), and BMDM-polarized M2 macrophages transfected with the negative control of si-CRNDE (M2-si-control-exo). (A) LncRNA CRNDE expression in indicated exosomes was detected by qRT-PCR. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. : one-way ANOVA. **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "Exosomes were isolated from the media of BMDMs (BMDMs-exo), BMDM-polarized  M2 macrophages (M2-exo), BMDM-polarized M2 macrophages transfected with si-CRNDE (M2-si-CRNDE-exo), and BMDM-polarized M2 macrophages transfected with the negative control of si-CRNDE (M2-si-control-exo). Then, MFC cells were treated with indicated exosomes  and cisplatin (CDDP; 1μg/ml) for 48 h. (C) Representative images of colony formation assay performed on MFC cells."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "Exosomes  were isolated from the medium of monocytes (monocytes-exo), monocyte-polarized M2 macrophages (M2-exo), monocyte-polarized M2 macrophages transfected with si-CRNDE (M2-si-CRNDE-exo), and monocyte-polarized M2 macrophages transfected with si-control (M2-si-control-exo). (E) LncRNA CRNDE expression were measured. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. one-way ANOVA. **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "Exosomes were isolated from the medium of monocytes (monocytes-exo), monocyte-polarized M2 macrophages  (M2-exo), monocyte-polarized M2 macrophages transfected with si-CRNDE (M2-si-CRNDE-exo), and  monocyte-polarized M2 macrophages transfected with si-control (M2-si-control-exo). Then, SGC7901 cells were treated with indicated exosomes and CDDP (1μg/ml). (G) cell proliferation  were measured."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "3×105 MFC cells were subcutaneously injected into nude mice. Ten days after injection, BMDMs-exo, M2-exo, M2-si-control-exo, or  M2-si-CRNDE-exo (10 µg) was injected into the center of the homograft tumors of mice (n=7 each group), followed by intraperitoneal injection of CDDP (10 mg/kg). Six days after CDDP treatment, all mice were sacrificed and the homograft tumors were collected. (A) Growth curves of MFC  subcutaneous homograft tumors (The homograft tumor sizes were recorded from the day of CDDP  treatment). *P&lt;0.05, **P&lt;0.01 vs. BMDMs-exo; #P&lt;0.05, ##P&lt;0.01 vs. M2-si-control-exo. Data information: Data are expressed as mean ± SD. one-way ANOVA."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "3×105 MFC cells were subcutaneously injected into nude mice. Ten days after injection, BMDMs-exo, M2-exo, M2-si-control-exo, or M2-si-CRNDE-exo (10 µg) was injected into the center of the homograft tumors of  mice  (n=7 each group), followed by intraperitoneal injection of CDDP (10 mg/kg). Six days after CDDP treatment, all mice  were sacrificed and the homograft tumors were collected. (D) LncRNA CRNDE expression in homograft tumors of  mice. **P&lt;0.01. Data information: Data are expressed as mean ± SD. : one-way ANOVA."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "(C) SGC7901 cells were transfected with pcDNA-CRNDE or its negative control (Mock) before MG132 treatment (10 µM, 6 h). The Co-immunoprecipitation (Co-IP) assay was performed to examine the combination of PTEN and NEDD4-1."
NCBI gene IDs:
"CRNDE: "
Figure legend: "(E) The  expressions of PTEN and  NEDD4-1 were measured in SGC7901 cells transfected with pcDNA-CRNDE or Mock at four time-points after cycloheximide (CHX, 100 μg/mL) treatment. GAPDH  was served as an internal control. Left: Representative bands. Right: Quantitative results. The results shown are from three biological replicates and are expressed as mean ± SD. Student's t-test. *P&lt;0.05, **P&lt;0.01 vs. Mock."
NCBI gene IDs:
"CRNDE: "
Figure legend: "Normal, si-control-transfected, or si-PTEN-transfected  SGC7901 cells were treated with CDDP (1 µg/ml) and M2-si-control-exo or M2-si-CRNDE-exo. Si-control, the negative control of si-PTEN. (A) The protein levels of  PTEN, phosphorylated phosphatidylinositol 3-kinase (p-PI3K), phosphorylated protein kinase B (p-AKT), p-glycoprotein (p-gp), B-cell lymphoma 2 (Bcl-2) were measured. GAPDH was served as an internal control."
NCBI gene IDs:
"CRNDE: 643911
PTEN: 5728"
Figure legend: "Normal, si-control-transfected, or si-PTEN-transfected  SGC7901 cells were treated with CDDP  (1 µg/ml) and M2-si-control-exo or M2-si-CRNDE-exo. Si-control, the negative control of si-PTEN. The cell apoptosis in SGC7901  cells. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. one-way ANOVA. **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911
PTEN: 5728"
Figure legend: "SGC7901  cells were divided into four groups: M2-si-control-exo, M2-si-CRNDE-exo, M2-si-CRNDE-exo +PTEN inhibitor (SF1670; 50 μmol/l), M2-si-control-exo+PTEN inhibitor. All cells were treated with  CDDP. The cell survival rate were measured. Data information: The results shown are from seven biological replicates. Data are expressed as mean ± SD. : one-way ANOVA. **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "SGC7901 cells were divided into four groups: M2-si-control-exo,  M2-si-CRNDE-exo, M2-si-CRNDE-exo +PTEN inhibitor (SF1670; 50 μmol/l), M2-si-control-exo+PTEN inhibitor. All cells were treated with CDDP. The cell apoptosis were measured. Data information: The results shown are from three biological replicates. Data are expressed as mean ± SD. one-way ANOVA. **P&lt;0.01."
NCBI gene IDs:
"CRNDE: 643911"
Figure legend: "C. As for A, but analysing Col/Ler SNPs/kb around crossovers from wild type, HEI10-OE, recq4a recq4b or HEI10-OE recq4a recq4b (Serra et al, 2018b). All populations were generated from Col×Ler hybrids. Printed beneath are the estimated average numbers of Class I and Class II crossovers per meiosis for each genotype, measured via genotyping-by-sequencing (Serra et al, 2018b; Ziolkowski et al, 2017). To the right are plots showing the significance of SNPs/kb differences between crossover sets, across the windows tested (Bonferroni adjusted t-tests)."
NCBI gene IDs:
"HEI10: 841784
recq4a: 837636
recq4b: 842384"
Figure legend: "A. Histograms of observed crossovers per F2 individual in the indicated wild type and msh2 populations, from Col×Ct, Col×Ler and Col×CLC crosses (blue). The Poisson expectation is plotted in red. Data from HEI10-OE, recq4a recq4b and HEI10-OE recq4a recq4b F2 populations are also shown for comparison (Serra et al, 2018b; Ziolkowski et al, 2017). Mean values are indicated by black dotted lines."
NCBI gene IDs:
"HEI10: 841784
msh2: 821383
recq4a: 837636
recq4b: 842384"
Figure legend: "B. Crossovers per 200 kb per F2 plotted along the Arabidopsis chromosomes, with mean values shown by horizontal dashed lines. Data are shown for wild type (red) and msh2 (blue) crossovers generated from Col×Ct, Col×Ler and Col×CLC hybrids. SNPs per 200 kb are shaded in colour (blue=Col/Ct, green=Col/Ler, pink=Col/Cvi). The positions of telomeres (TEL) and centromeres (CEN) are labeled. The number of crossovers analysed is printed inset. C. Data as for B, but analyzing crossovers in wild type (red) and msh2 (blue), or SNPs along proportionally scaled chromosome arms orientated from telomeres (TEL) to centromeres (CEN). Crossover data from HEI10-OE, recq4a recq4b and HEI10-OE recq4a recq4b Col×Ler F2 populations are also shown (Serra et al, 2018b; Ziolkowski et al, 2017)."
NCBI gene IDs:
"HEI10: 
HEI10: 841784
msh2: 821383
recq4a: 837636
recq4b: 842384"
Figure legend: "B. SNPs/kb values were calculated in physical windows of increasing size (kb) around crossover midpoints in wild type (red) and msh2 (blue). The same values were calculated for matched randomly chosen positions (grey). Printed above the plot for each window are circles that are coloured green if crossover SNPs/kb values are significantly different to random (P&lt;0.05), or red if not (P&gt;0.05) (Bonferroni adjusted t-tests). The population analysed (Col×Ct, Col×Ler, Col×CLC) and its genome average SNP frequency (SNPs/kb) is printed above the plots and the number of crossover positions analysed is printed inset. Beneath are plots showing the significance of SNPs/kb differences around crossovers between the indicated genotypes."
NCBI gene IDs:
"msh2: 821383"
Figure legend: "A. Representative DAPI-stained spreads of pachytene, diakinesis, metaphase-I, dyad and tetrad meiotic stages, for wild type and msh2, in Col×Ler or Col×CLC hybrid backgrounds."
NCBI gene IDs:
"msh2: 821383"
Figure legend: "B. Male meiocytes immunostained for MSH2 (red) and ASY1 (green), and stained for DAPI (blue) in wild type (Col) or msh2."
NCBI gene IDs:
"msh2: 821383"
Figure legend: "C. 420 crossover frequency (cM) in the HOM-HOM, HET-HET, HET-HOM, HOM-HET genotypes shown in B, in either wild type or msh2. Values for replicate individuals are plotted, in addition to the mean (red)."
NCBI gene IDs:
"msh2: 821383"
Figure legend: "D. As for C, but comparing genotypes in wild type or HEI10-OE backgrounds. Values for replicate individuals are plotted, in addition to the mean (red)."
NCBI gene IDs:
"HEI10: 841784"
Figure legend: "(H) The  bur1-ΔC mutant exhibits a synthetic growth defect with the  vac17Δ mutant. Plasmids were transformed into a bur1Δ or  bur1Δ vac17Δ mutant containing YCp50 [URA3] BUR1. Plasmids tested were pRS415 [LEU2] (mock), pRS415 BUR1, or pRS415 bur1-ΔC. Transformed colonies were cultured in liquid medium and serial dilutions spotted onto SC+5-FOA or SC-Leu-Ura  plates. Plates were incubated at 24 ̊C for 3 days."
NCBI gene IDs:
"LEU2: 850342
bur1: 856290
BUR1: 856290
URA3: 856692
vac17: 850296"
Figure legend: "(A, B) The  bur1-ΔC  vac17Δ double mutant exhibits a delay in progression  through  G1  phase of the cell cycle. Yeast were grown in  YPD  medium and collected in log phase growth. DNA content was measured using propidium iodide (PI) staining  and assessed by  flow cytometry. p-value determined with a one-way ANOVA and Tukey post hoc test. ** (p-value &lt; 1 x 10-2). Error bars; SD calculated from at least four independent experiments with at least 100 cells counted in each strain/experiment. (C, D) A bur1-267 mutant also exhibits a delay in progression through  G1  phase of the  cell cycle. DNA content was measured using   PI staining and assessed by flow cytometry. p-value determined with a one-way ANOVA and Tukey post hoc test. **** (p-value &lt; 1 x 10-4). Error bars; SD calculated from at least four independent experiments with at least 100 cells counted in each strain/experiment."
NCBI gene IDs:
"bur1: 856290
vac17: 850296"
Figure legend: "(E, F) The bur1-ΔC  vac17Δ double mutant shows accumulation of Whi5 in the nucleus. WT, vac17Δ, bur1-ΔC, and bur1-ΔC vac17Δ cells, which express Whi5-3xGFP and  Nup188-mCherry from endogenous loci, were incubated at 24 ̊C. Cells were scored for the presence of Whi5-3xGFP in within the nucleus (Nup188-mCherry). Error bars; SD calculated from at least four independent experiments with at least 100 cells counted in each strain/experiment. p-value determined with a one-way ANOVA and Tukey post hoc test. ** (p-value &lt; 1 x 10-2). Error bars; SD calculated from at least four independent experiments with at least 100 cells counted in each strain/experiment. Scale bar, 2 μm."
NCBI gene IDs:
"bur1: 856290
vac17: 850296"
Figure legend: "(B) The bur1-∆C vac17∆ double mutant cells have the ability to generate a  vacuole de novo, which suggests that the  cell-cycle delay is due to a defect in Bur1-dependent signaling. WT, vac17Δ, bur1-∆C, and bur1-∆C vac17∆ cells which express  Vph1-GFP from its endogenous locus, were  pulse labeled with the  vacuole specific dye FM4-64. WT and bur1-∆C cells have both FM4-64 and Vph1-GFP  signals in both mother and daughter cells. vac17Δ and bur1-∆C vac17∆ cells have both  Vph1-GFP  and  FM4-64 on the vacuole in mother cells, however the daughter cells solely have a Vph1-GFP labeled vacuole, indicating that the vacuole was generated de novo, rather than inherited from the mother vacuole. Arrowheads; new vacuoles in daughter cells. Scale bar, 2 μm."
NCBI gene IDs:
"bur1: 856290
Bur1: 856290
vac17: 850296"
Figure legend: "(A) In vivo phosphorylation  of Sch9  is reduced in  bur1-∆C vac17∆ cells. WT, bur1-∆C, vac17∆, or  bur1-∆C vac17∆ cells expressing SCH9-HA from the URA3 locus were grown in  YPD. Cell lysates were analyzed by immunoblot  with antibodies directed against  HA (top) and Pgk1 (loading control). (B) In vivo phosphorylation of Sch9 is reduced in bur1-267 cells. WT, vac17∆, bur1-267, or  bur1-267 vac17∆ cells expressing SCH9-HA from the URA3  locus were grown in  YPD. Cell lysates were analyzed by immunoblot with antibodies directed against  HA (top) and Pgk1  (loading control)."
NCBI gene IDs:
"bur1: 856290
URA3: 856692
vac17: 850296"
Figure legend: "(C) bur1-∆C shows high rapamycin sensitivity. WT, tor1∆, bur1-∆C,  tor1∆ bur1-∆C or vac17∆ cells were cultured in liquid YPD medium and serial dilutions were spotted onto YPD plates with 0, 2, 4 or 8 ng/ml of  rapamycin added. Plates were incubated at 24 ̊C for 2 days."
NCBI gene IDs:
"bur1: 856290
tor1: 853529
vac17: 850296"
Figure legend: "(B) In vitro, Bur1 directly phosphorylates the kinase domain of Sch9 as well as Bur1  itself. pRS425 BUR1-HA and pVT102-Ura BUR2, the essential cyclin for BUR1, were co-expressed in a bur1Δ mutant, immunoprecipitated using anti-HA antibody and protein A  beads, and then incubated with [γ-32P]ATP  and GST, GST-N-Sch9  (1-390) or GST-C-Sch9  (391-824). Proteins were eluted with SDS  sample buffer, separated by  SDS-PAGE, and transferred to  nitrocellulose  membranes. Membranes exposed to x-ray film (top) or stained  with Ponceau S (bottom). Red arrowhead; phosphorylated GST-C-Sch9. Gray arrowhead; auto-phosphorylated Bur1."
NCBI gene IDs:
"HA: 
BUR2: 850923
BUR1: 856290
bur1: 856290"
Figure legend: "(D)  Sch9-2D3E, but not Sch9-3A-2D3E, partially suppressed the rapamycin sensitivity of tor1∆ cells.  tor1∆ which expresses pRS426 (mock), pRS425 TOR1, pVT102-Ura (mock), pVT102-Ura Sch9, pVT102-Ura Sch9-2D3E, or pVT102-Ura Sch9-3A-2D3E, were cultured in liquid SC-Ura  medium and serial dilutions spotted onto SC-Ura plates with 0 or 8 ng/ml of rapamycin added. Plates were incubated at 24 ̊C for 2-3 days."
NCBI gene IDs:
"Sch9: 856612
tor1: 853529
TOR1: 853529"
Figure legend: "(E) The  Sch9-2D3E mutant did not suppress the rapamycin sensitivity of bur1-∆C cells. bur1-∆C which expresses pRS426 (mock), pRS426 BUR1, pVT102-Ura (mock), pVT102-Ura SCH9, pVT102-Ura sch9-2D3E, pVT102-Ura sch9-3A-2D3E, pVT102-Ura sch9-3D/E, or pVT102-Ura sch9-3D/E-2D3E were cultured in liquid  SC-Ura medium and serial dilutions spotted onto  SC-Ura plates with 0 or 8 ng/ml of  rapamycin  added. Plates were incubated at 24 ̊C for 3 days."
NCBI gene IDs:
"sch9: 856612
Sch9: 856612
SCH9: 856612
bur1: 856290
BUR1: 856290"
Figure legend: "(A) Bur1  fused SV40-NLS does not rescue the rapamycin sensitivity of bur1-∆C compared to Bur1 without the NLS. bur1-∆C which expresses pRS416 (mock), pRS416 BUR1, pRS416 BUR1-mNG, pRS416 BUR1-mNG-NLS, pRS416 bur1-∆C, pRS416  bur1-∆C-mNG-NLS or pRS416 bur1-∆N, were cultured in liquid SC-Ura medium and serial dilutions spotted onto SC-Ura plates with 0, 4, 8, or 16 ng/ml of rapamycin added. Plates were incubated at 24 ̊C for 2 days."
NCBI gene IDs:
"mNG: 
bur1: 856290
Bur1: 856290
BUR1: 856290"
Figure legend: "(B) Adding nuclear-export signal (NES) of PKI to Bur1 and/or deletion of the   importin α-dependent NLS  from  Bur1  resulted in higher sensitivity to rapamycin compared to Bur1  without this NES. bur1-∆C which expresses pRS426 (mock), pRS426 BUR1, pRS426 bur1-∆N, pRS426  BUR1-mNG, pRS426 BUR1-mNG-NES, or pRS426 bur1-∆N-mNG-NES, were cultured in liquid  SC-Ura medium and serial dilutions spotted onto SC-Ura plates with 0, 4, 8, or 16 ng/ml of  rapamycin added. Plates were incubated at 24 ̊C for 2 days."
NCBI gene IDs:
"mNG: 
BUR1: 856290
Bur1: 856290
bur1: 856290"
Figure legend: "Representative flow cytometric showing the specific depletion efficiency of ATM subsets from eWAT of CD169-DTR ND- (A) or HFD-treated (16 weeks) (B) mice. A representative analysis of three independent experiments is shown."
NCBI gene IDs:
"DTR: 15200
CD169: 20612"