Original: It flows west to east and crosses the Paktia Province Afghan-Pakistan border at  about 80 km southwest of Jalalabad, and joins the Indus near Isa Khel after a course of more than 320 km (200 miles).
Simplified: It crosses the Afghan-Pakistan border about 80 km southwest of Jalalabad, and joins the Indus near Isa Khel after a course of more than 320 km (200 miles).