Original: Sprains can best be prevented by proper use of safety equipment (wrist, ankle guards; carts vs. lifting), warm-ups and cool-downs (including stretching), being aware of surroundings and maintaining strength and flexibility.
Simplified: Sprains can best be prevented by proper use of safety equipment (wrist, ankle guards), warm-ups and cool-downs (including stretching), being aware of your surroundings and maintaining strength and flexibility.