Claim: PMS2 has been shown to interact with MLH1, though there is competition between MLH3, PMS1, and PMS2 for the interacting domain on MLH1.
Evidence: PMS2 has been shown to interact with MLH1 by forming the heterodimer MutLα. There is competition between MLH3, PMS1, and PMS2 for the interacting domain on MLH1, which is located in residues 492-742.