Claim: Cowpea chlorotic mottle virus is dependent on aspecific binding and it takes advantage if the membrane which is where the most effective infections can occur.
Evidence: One study examined the interactions between CCMV and cowpea protoplasts and found that it was dependent on aspecific binding, mostly relying on electrostatic interactions between the plasma membrane and virus particles, specifically negatively charged vesicles and the positively charged N-terminal arm of viral coat proteins, further labelling CCMV as an endocytic virus. It also takes advantage of membrane lesions to introduce viral particles into the cell. Overall, the most effective infection occurred by internalization through membrane lesions of the host.