Claim: South Carolina Highway 341, which actually runs diagonally from the southeast to northwest (but signed as north-south), has major junctions in the county of Florence for cities such as Lake City, and Bethune, for the county of Sumter, and for the county of Lee for cities such as Lynchburg and Wisacky.
Evidence: South Carolina Highway 341 (SC 341) is a 93.9-mile-long (151.1 km) state highway that runs through northeastern South Carolina. It runs diagonally from the southeast to northwest (but signed as north-south) from SC 41 and SC 51 in Johnsonville to U.S. Route 521 Business (US 521 Bus.) Florence Lake City Sumter Lee Lynchburg Wisacky