Target-Controlled Drug Delivery: Progress Toward an Intravenous "Vaporizer" and Automated Anesthetic Administration
Based on a drug's typical pharmacokinetic behavior, target-controlled infusion systems calculate and deliver the infusion rate that is necessary to achieve and maintain a user-designated drug concentration in the blood or theoretical effect site. Employed in both clinical and research settings, target-controlled infusion technology represents an important advance in the delivery of intravenous anesthetics.