Drug metabolizing ability in operating theatre personnel
Drug metabolizing ability was determined in a group of anesthetists and other operating theatre personnel. Two indices were used: plasma antipyrine half life and plasma γ glutamyl transpeptidase activity (γ GPT). The plasma clearance of antipyrine (2.93 ± 0.79 l./hr mean ± SD) was significantly faster (21%) in the operating theatre exposed group than in the matched controls (2.46 ± 0.76 l./hr).