Druvith/medqa1 huggingface dataset:
Question:  What are the symptoms of Peripheral Arterial Disease (P.A.D.) ?
Answer: People who have P.A.D. may have symptoms when walking or climbing stairs. These may include pain, numbness, aching, or heaviness in the leg muscles. Symptoms may also include cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. Some possible signs of P.A.D. include - weak or absent pulses in the legs or feet  - sores or wounds on the toes, feet, or legs that heal slowly  - a pale or bluish color to the skin  - poor nail growth on the toes and decreased hair growth on the legs  - erectile dysfunction, especially among men who have diabetes. weak or absent pulses in the legs or feet sores or wounds on the toes, feet, or legs that heal slowly a pale or bluish color to the skin poor nail growth on the toes and decreased hair growth on the legs erectile dysfunction, especially among men who have diabetes.
Question:  How to diagnose Peripheral Arterial Disease (P.A.D.) ?
Answer: There are several tests used to diagnose P.A.D. These include - an ankle-brachial index (ABI). This test compares blood pressure in your ankle to blood pressure in your arm. It shows how well blood is flowing in your limbs.  - a Doppler ultrasound. This test uses sound waves to show whether a blood vessel is blocked. A blood pressure cuff and special device measure blood flow in the veins and arteries of the limbs. A Doppler ultrasound can help find out how where P.A.D. is.   - a treadmill test. This test shows if you have any problems during normal walking, how severe your symptoms are, and what level of exercise brings them on.  - a magnetic resonance angiogram (MRA). This test uses magnetic and radio waves to take pictures of your blood vessels. An MRA can find the location of a blocked blood vessel and show how severe the blockage is.   - an arteriogram. This test is used to find the exact location of a blocked artery. Dye is injected through a needle or catheter (thin tube) into an artery, then an X-ray is taken. The pictures from the X-ray can show the location, type, and extent of the blockage in the artery.   - blood tests. These tests check for P.A.D. risk factors such as diabetes and high blood cholesterol levels.  an ankle-brachial index (ABI). This test compares blood pressure in your ankle to blood pressure in your arm. It shows how well blood is flowing in your limbs. a Doppler ultrasound. This test uses sound waves to show whether a blood vessel is blocked. A blood pressure cuff and special device measure blood flow in the veins and arteries of the limbs. A Doppler ultrasound can help find out how where P.A.D. is. a treadmill test. This test shows if you have any problems during normal walking, how severe your symptoms are, and what level of exercise brings them on. a magnetic resonance angiogram (MRA). This test uses magnetic and radio waves to take pictures of your blood vessels. An MRA can find the location of a blocked blood vessel and show how severe the blockage is. an arteriogram. This test is used to find the exact location of a blocked artery. Dye is injected through a needle or catheter (thin tube) into an artery, then an X-ray is taken. The pictures from the X-ray can show the location, type, and extent of the blockage in the artery. blood tests. These tests check for P.A.D. risk factors such as diabetes and high blood cholesterol levels.
Question:  How to prevent Peripheral Arterial Disease (P.A.D.) ?
Answer: Treatment and prevention for P.A.D. often includes making long-lasting lifestyle changes, such as - quitting smoking  - lowering blood pressure  - lowering high blood cholesterol levels  - lowering high blood glucose levels if you have diabetes  - getting regular physical activity  - following a healthy eating plan that's low in total fat, saturated fat, trans fat, cholesterol, and sodium (salt). quitting smoking lowering blood pressure lowering high blood cholesterol levels lowering high blood glucose levels if you have diabetes getting regular physical activity following a healthy eating plan that's low in total fat, saturated fat, trans fat, cholesterol, and sodium (salt). Two examples of healthy eating plans are Therapeutic Lifestyle Changes (TLC) and  Dietary Approaches to Stop Hypertension (DASH).
Question:  what research (or clinical trials) is being done for Peripheral Arterial Disease (P.A.D.) ?
Answer: The National Heart, Lung, and Blood Institute (NHLBI) supports research aimed at learning more about peripheral arterial disease (P.A.D.). For example, NHLBI-supported research on P.A.D. includes studies that - explore whether group walking sessions increase physical activity in people who have P.A.D.  - compare how effective certain exercise programs are at reducing leg pain in people who have P.A.D.  - examine how inflammation and insulin resistance affect people who have P.A.D.  explore whether group walking sessions increase physical activity in people who have P.A.D. compare how effective certain exercise programs are at reducing leg pain in people who have P.A.D. examine how inflammation and insulin resistance affect people who have P.A.D. Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and ways to improve health. For more information about clinical trials related to P.A.D., talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials. - http://www.nih.gov/health/clinicaltrials/  - http://www.clinicaltrials.gov/  - http://www.nhlbi.nih.gov/studies/index.htm  - https://www.researchmatch.org/  - http://www.cleverstudy.org/ http://www.nih.gov/health/clinicaltrials/ http://www.clinicaltrials.gov/ http://www.nhlbi.nih.gov/studies/index.htm https://www.researchmatch.org/ http://www.cleverstudy.org/
Question:  What is (are) Peripheral Arterial Disease (P.A.D.) ?
Answer: Here are links to more information about P.A.D. from the National Heart, Lung, and Blood Institute. -  What Is Peripheral Arterial Disease?  -  Atherosclerosis  -  The DASH Eating Plan  - Facts about P.A.D.   - Facts about P.A.D. (Spanish)  - Facts About P.A.D. for African Americans  -  Keep the Beat: Heart Healthy Recipes  - Smoking and Your Heart  -   Your Guide to Physical Activity and Your Heart  -  Stay in Circulation: Take Steps to Learn about P.A.D. - Stay in Circulation: Take Steps to Learn about P.A.D. Wallet Card  - Your Guide to Lowering Your Blood Pressure with DASH  -  Your Guide to Lowering Your Cholesterol with TLC What Is Peripheral Arterial Disease? Atherosclerosis The DASH Eating Plan Facts about P.A.D.  Facts about P.A.D. (Spanish) Facts About P.A.D. for African Americans  Keep the Beat: Heart Healthy Recipes Smoking and Your Heart  Your Guide to Physical Activity and Your Heart Stay in Circulation: Take Steps to Learn about P.A.D. Stay in Circulation: Take Steps to Learn about P.A.D. Wallet Card Your Guide to Lowering Your Blood Pressure with DASH Your Guide to Lowering Your Cholesterol with TLC For print resources and materials on P.A.D. visit http://www.nhlbi.nih.gov/health/public/heart/pad/index.html
Question:  What is (are) Rheumatoid Arthritis ?
Answer: An Inflammatory, Autoimmune Disease Rheumatoid arthritis is an inflammatory disease that causes pain, swelling, stiffness, and loss of function in the joints. It can cause mild to severe symptoms. Rheumatoid arthritis not only affects the joints, but may also attack tissue in the skin, lungs, eyes, and blood vessels. People with rheumatoid arthritis may feel sick, tired, and sometimes feverish. Rheumatoid arthritis is classified as an autoimmune disease. An autoimmune disease occurs when the immune system turns against parts of the body it is designed to protect. Rheumatoid arthritis generally occurs in a symmetrical pattern. This means that if one knee or hand is involved, the other one is, too. It can occur at any age, but usually begins during a person's most productive years. Affects More Women Than Men Rheumatoid arthritis occurs much more frequently in women than in men. About two to three times as many women as men have the disease. Learn more about how rheumatoid arthritis occurs.  Effects Vary Rheumatoid arthritis affects people differently. Some people have mild or moderate forms of the disease, with periods of worsening symptoms, called flares, and periods in which they feel better, called remissions. Others have a severe form of the disease that is active most of the time, lasts for many years or a lifetime, and leads to serious joint damage and disability. Although rheumatoid arthritis is primarily a disease of the joints, its effects are not just physical. Many people with rheumatoid arthritis also experience issues related to - depression, anxiety  - feelings of helplessness  - low self-esteem. depression, anxiety feelings of helplessness low self-esteem. Rheumatoid arthritis can affect virtually every area of a persons life from work life to family life. It can also interfere with the joys and responsibilities of family life and may affect the decision to have children. Treatment Can Help Fortunately, current treatment strategies allow most people with the disease to lead active and productive lives. These strategies include pain-relieving drugs and medications that slow joint damage, a balance between rest and exercise, and patient education and support programs. In recent years, research has led to a new understanding of rheumatoid arthritis and has increased the likelihood that, in time, researchers will find even better ways to treat the disease.
Question:  What causes Rheumatoid Arthritis ?
Answer: Actual Cause Is Unknown Scientists believe that rheumatoid arthritis may result from the interaction of many factors such as genetics, hormones, and the environment. Although rheumatoid arthritis sometimes runs in families, the actual cause of rheumatoid arthritis is still unknown. Research suggests that a person's genetic makeup is an important part of the picture, but not the whole story. Some evidence shows that infectious agents, such as viruses and bacteria, may trigger rheumatoid arthritis in people with an inherited tendency to develop the disease. However, a specific agent or agents are not yet known. Not Contagious It is important to note that rheumatoid arthritis is not contagious. A person cannot catch it from someone else.  Learn more about the causes of rheumatoid arthritis.
Question:  What are the symptoms of Rheumatoid Arthritis ?
Answer: Swelling and Pain in the Joints Different types of arthritis have different symptoms. In general, people with most forms of arthritis have pain and stiffness in their joints. Rheumatoid arthritis is characterized by inflammation of the joint lining. This inflammation causes warmth, redness, swelling, and pain around the joints. A person also feels sick, tired, and sometimes feverish. Rheumatoid arthritis generally occurs in a symmetrical pattern. If one knee or hand is affected, the other one is also likely to be affected. Diagnostic Tests Rheumatoid arthritis can be difficult to diagnose in its early stages for several reasons. There is no single test for the disease. In addition, symptoms differ from person to person and can be more severe in some people than in others. Common tests for rheumatoid arthritis include - The rheumatoid factor test. Rheumatoid factor is an antibody that is present eventually in the blood of most people with rheumatoid arthritis However, not all people with rheumatoid arthritis test positive for rheumatoid factor, especially early in the disease. Also, some people who do test positive never develop the disease. The rheumatoid factor test. Rheumatoid factor is an antibody that is present eventually in the blood of most people with rheumatoid arthritis However, not all people with rheumatoid arthritis test positive for rheumatoid factor, especially early in the disease. Also, some people who do test positive never develop the disease. -  The citrulline antibody test. This blood test detects antibodies to cyclic citrullinated peptide (anti-CCP). This test is positive in most people with rheumatoid arthritis and can even be positive years before rheumatoid arthritis symptoms develop. When used with the rheumatoid factor test, the citrulline antibody test results are very useful in confirming a rheumatoid arthritis diagnosis.  The citrulline antibody test. This blood test detects antibodies to cyclic citrullinated peptide (anti-CCP). This test is positive in most people with rheumatoid arthritis and can even be positive years before rheumatoid arthritis symptoms develop. When used with the rheumatoid factor test, the citrulline antibody test results are very useful in confirming a rheumatoid arthritis diagnosis. Other common tests for rheumatoid arthritis include - the erythrocyte sedimentation rate, which indicates the presence of inflammation in the body  - a test for white blood cell count and  - a blood test for anemia.  the erythrocyte sedimentation rate, which indicates the presence of inflammation in the body a test for white blood cell count and a blood test for anemia. Diagnosis Can Take Time Symptoms of rheumatoid arthritis can be similar to those of other types of arthritis and joint conditions, and it may take some time to rule out other conditions. The full range of symptoms develops over time, and only a few symptoms may be present in the early stages. Learn more about how rheumatoid arthritis is diagnosed.
Question:  what research (or clinical trials) is being done for Rheumatoid Arthritis ?
Answer: Scientists are making rapid progress in understanding the complexities of rheumatoid arthritis. They are learning more about how and why it develops and why some people have more severe symptoms than others. Research efforts are focused on developing drugs that can reduce inflammation and slow or stop the disease with few side effects. Identifying Possible Triggers Some evidence shows that infectious agents, such as viruses and bacteria, may contribute to triggering rheumatoid arthritis in people with an inherited tendency to develop the disease. Investigators are trying to identify the infectious agents and understand how they work. This knowledge could lead to new therapies. Why More Women Than Men? Researchers are also exploring why so many more women than men develop rheumatoid arthritis. In the hope of finding clues, they are studying complex relationships between the hormonal, nervous, and immune systems in rheumatoid arthritis. For example, they are exploring whether and how the normal changes in the levels of steroid hormones such as estrogen and testosterone during a person's lifetime may be related to the development, improvement, or flares of the disease. Scientists are also examining why rheumatoid arthritis often improves during pregnancy. Learn more about current research on rheumatoid arthritis. Interested in Clinical Trials? The U.S. National Institutes of Health, through its National Library of Medicine and other Institutes, maintains a database of clinical trials at Clinical Trials.gov.  To see a list of current clinical trials on rheumatoid arthritis, type "rheumatoid arthritis" into the search box.
Question:  What is (are) Rheumatoid Arthritis ?
Answer: Rheumatoid arthritis is an inflammatory disease that causes pain, swelling, stiffness, and loss of function in the joints. It can cause mild to severe symptoms. People with rheumatoid arthritis may feel sick, tired, and sometimes feverish. Sometimes rheumatoid arthritis attacks tissue in the skin, lungs, eyes, and blood vessels. The disease generally occurs in a symmetrical pattern. If one knee or hand is involved, usually the other one is, too. It can occur at any age, but often begins between ages 40 and 60. About two to three times as many women as men have rheumatoid arthritis. Learn more about how rheumatoid arthritis occurs.
Question:  What causes Rheumatoid Arthritis ?
Answer: Scientists believe that rheumatoid arthritis may result from the interaction of many factors such as genetics, hormones, and the environment. Although rheumatoid arthritis sometimes runs in families, the actual cause of rheumatoid arthritis is still unknown. Research suggests that a person's genetic makeup is an important part of the picture, but not the whole story. Some evidence shows that infectious agents, such as viruses and bacteria, may trigger rheumatoid arthritis in people with an inherited tendency to develop the disease. The exact agent or agents, however, are not yet known. It is important to note that rheumatoid arthritis is not contagious. A person cannot catch it from someone else. Learn more about the causes of rheumatoid arthritis.
Question:  What are the symptoms of Rheumatoid Arthritis ?
Answer: Rheumatoid arthritis is characterized by inflammation of the joint lining. This inflammation causes warmth, redness, swelling, and pain around the joints. The pain of rheumatoid arthritis varies greatly from person to person, for reasons that doctors do not yet understand completely. Factors that contribute to the pain include swelling within the joint, the amount of heat or redness present, or damage that has occurred within the joint.
Question:  How to diagnose Rheumatoid Arthritis ?
Answer: Rheumatoid arthritis can be difficult to diagnose in its early stages because the full range of symptoms develops over time, and only a few symptoms may be present in the early stages. As part of the diagnosis, your doctor will look for symptoms such as swelling, warmth, pain, and limitations in joint motion throughout your body. Your doctor may ask you questions about the intensity of your pain symptoms, how often they occur, and what makes the pain better or worse.
Question:  How to diagnose Rheumatoid Arthritis ?
Answer: There is no single, definitive test for rheumatoid arthritis. Common tests for rheumatoid arthritis include - The rheumatoid factor test. Rheumatoid factor is an antibody that is present eventually in the blood of most people with rheumatoid arthritis. However, not all people with rheumatoid arthritis test positive for rheumatoid factor, especially early in the disease. Also, some people who do test positive never develop the disease.  The rheumatoid factor test. Rheumatoid factor is an antibody that is present eventually in the blood of most people with rheumatoid arthritis. However, not all people with rheumatoid arthritis test positive for rheumatoid factor, especially early in the disease. Also, some people who do test positive never develop the disease. - The citrulline antibody test. This blood test detects antibodies to cyclic citrullinated peptide (anti-CCP). This test is positive in most people with rheumatoid arthritis and can even be positive years before rheumatoid arthritis symptoms develop. When used with the rheumatoid factor test, the citrulline antibody test results are very useful in confirming a rheumatoid arthritis diagnosis.  The citrulline antibody test. This blood test detects antibodies to cyclic citrullinated peptide (anti-CCP). This test is positive in most people with rheumatoid arthritis and can even be positive years before rheumatoid arthritis symptoms develop. When used with the rheumatoid factor test, the citrulline antibody test results are very useful in confirming a rheumatoid arthritis diagnosis. Other common tests for rheumatoid arthritis include - the erythrocyte sedimentation rate, which indicates the presence of inflammation in the body   - a test for white blood cell count   - a blood test for anemia.  the erythrocyte sedimentation rate, which indicates the presence of inflammation in the body a test for white blood cell count a blood test for anemia. X-rays are often used to determine the degree of joint destruction. They are not useful in the early stages of rheumatoid arthritis before bone damage is evident, but they can be used later to monitor the progression of the disease. Learn more about how rheumatoid arthritis is diagnosed.
Question:  What are the treatments for Rheumatoid Arthritis ?
Answer: Medication, exercise, and, in some cases, surgery are common treatments for this disease. Most people who have rheumatoid arthritis take medications. Some drugs only provide relief for pain; others reduce inflammation. People with rheumatoid arthritis can also benefit from exercise, but they need to maintain a good balance between rest and exercise. They should get rest when the disease is active and get more exercise when it is not. In some cases, a doctor will recommend surgery to restore function or relieve pain in a damaged joint. Several types of surgery are available to patients with severe joint damage. Joint replacement and tendon reconstruction are examples.
Question:  What are the treatments for Rheumatoid Arthritis ?
Answer: Most people who have rheumatoid arthritis take medications. Some drugs only provide relief for pain; others reduce inflammation. Still others, called disease-modifying anti-rheumatic drugs or DMARDs, can often slow the course of the disease. - DMARDs include methotrexate, leflunomide, sulfasalazine, and cyclosporine.   - Steroids, which are also called corticosteroids, are another type of drug used to reduce inflammation for people with rheumatoid arthritis. Cortisone, hydrocortisone, and prednisone are some commonly used steroids.   - DMARDs called biological response modifiers also can help reduce joint damage. These drugs include etanercept, infliximab, and anakinra.   - Another DMARD, tofacitinib, from a new class of drugs called jak kinase (JAK) inhibitors is also available.  DMARDs include methotrexate, leflunomide, sulfasalazine, and cyclosporine. Steroids, which are also called corticosteroids, are another type of drug used to reduce inflammation for people with rheumatoid arthritis. Cortisone, hydrocortisone, and prednisone are some commonly used steroids. DMARDs called biological response modifiers also can help reduce joint damage. These drugs include etanercept, infliximab, and anakinra. Another DMARD, tofacitinib, from a new class of drugs called jak kinase (JAK) inhibitors is also available. Early treatment with powerful drugs and drug combinations -- including biological response modifiers and DMARDs -- instead of single drugs may help prevent the disease from progressing and greatly reduce joint damage.