Druvith/medqa huggingface dataset:
what research (or clinical trials) is being done for Adult Non-Hodgkin Lymphoma ? 

New types of treatment are being tested in clinical trials.
				                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Vaccine therapy     Vaccine therapy is a type of biologic therapy. Biologic therapy is a treatment that uses the patients immune system to fight cancer. Substances made by the body or made in a laboratory are used to boost, direct, or restore the bodys natural defenses against cancer. This type of cancer treatment is also called biotherapy or immunotherapy. Vaccine therapy can also be a type of targeted therapy.
				                
				                
				                    Patients may want to think about taking part in a clinical trial.
				                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
				                
				                
				                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
				                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Who is at risk for Adult Non-Hodgkin Lymphoma? ? 

Age, gender, and a weakened immune system can affect the risk of adult non-Hodgkin lymphoma. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your doctor if you think you may be at risk.    These and other risk factors may increase the risk of certain types of adult non-Hodgkin lymphoma:         - Being older, male, or white.    - Having one of the following medical conditions:               - An inherited immune disorder (such as hypogammaglobulinemia or Wiskott-Aldrich syndrome).      - An autoimmune disease (such as rheumatoid arthritis, psoriasis, or Sjgren syndrome).      - HIV/AIDS.      - Human T-lymphotrophic virus type I or Epstein-Barr virus infection.      - Helicobacter pylori infection.             - Taking immunosuppressant drugs after an organ transplant.
What are the symptoms of Adult Non-Hodgkin Lymphoma ? 

Signs and symptoms of adult non-Hodgkin lymphoma include swelling in the lymph nodes, fever, night sweats, weight loss, and fatigue. These signs and symptoms may be caused by adult non-Hodgkin lymphoma or by other conditions. Check with your doctor if you have any of the following:         - Swelling in the lymph nodes in the neck, underarm, groin, or stomach.    - Fever for no known reason.    - Recurring night sweats.    - Feeling very tired.    - Weight loss for no known reason.    - Skin rash or itchy skin.    - Pain in the chest, abdomen, or bones for no known reason.        When fever, night sweats, and weight loss occur together, this group of symptoms is called B symptoms.    Other signs and symptoms of adult non-Hodgkin lymphoma may occur and depend on the following:          - Where the cancer forms in the body.    - The size of the tumor.    - How fast the tumor grows.
What is the outlook for Adult Non-Hodgkin Lymphoma ? 

Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer.    - The type of non-Hodgkin lymphoma.     - The amount of lactate dehydrogenase (LDH) in the blood.    - Whether there are certain changes in the genes.    - The patients age and general health.    - Whether the lymphoma has just been diagnosed or has recurred (come back).        For non-Hodgkin lymphoma during pregnancy, the treatment options also depend on:         - The wishes of the patient.    - Which trimester of pregnancy the patient is in.    - Whether the baby can be delivered early.        Some types of non-Hodgkin lymphoma spread more quickly than others do. Most non-Hodgkin lymphomas that occur during pregnancy are aggressive. Delaying treatment of aggressive lymphoma until after the baby is born may lessen the mother's chance of survival. Immediate treatment is often recommended, even during pregnancy.
What causes Childhood Brain and Spinal Cord Tumors ? 

The cause of most childhood brain and spinal cord tumors is unknown.
What are the symptoms of Childhood Brain and Spinal Cord Tumors ? 

The signs and symptoms of childhood brain and spinal cord tumors are not the same in every child. Signs and symptoms depend on the following:         - Where the tumor forms in the brain or spinal cord.    - The size of the tumor.    - How fast the tumor grows.    - The child's age and development.        Signs and symptoms may be caused by childhood brain and spinal cord tumors or by other conditions, including cancer that has spread to the brain. Check with your child's doctor if your child has any of the following:      Brain Tumor Signs and Symptoms       - Morning headache or headache that goes away after vomiting.    - Frequent nausea and vomiting.     - Vision, hearing, and speech problems.    - Loss of balance and trouble walking.    - Unusual sleepiness or change in activity level.     - Unusual changes in personality or behavior.    -  Seizures.    - Increase in the head size (in infants).           Spinal Cord Tumor Signs and Symptoms       - Back pain or pain that spreads from the back towards the arms or legs.    - A change in bowel habits or trouble urinating.    - Weakness in the legs.    - Trouble walking.        In addition to these signs and symptoms of brain and spinal cord tumors, some children are unable to reach certain growth and development milestones such as sitting up, walking, and talking in sentences.
How to diagnose Childhood Brain and Spinal Cord Tumors ? 

Tests that examine the brain and spinal cord are used to detect (find) childhood brain and spinal cord tumors. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.     -   Neurological exam : A series of questions and tests to check the brain, spinal cord, and nerve function. The exam checks a persons mental status, coordination, and ability to walk normally, and how well the muscles, senses, and reflexes work. This may also be called a neuro exam or a neurologic exam.     -   MRI (magnetic resonance imaging) with gadolinium : A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of the brain and spinal cord. A substance called gadolinium is injected into a vein. The gadolinium collects around the cancer cells so they show up brighter in the picture. This procedure is also called nuclear magnetic resonance imaging (NMRI).    -   Serum tumor marker test : A procedure in which a sample of blood is examined to measure the amounts of certain substances released into the blood by organs, tissues, or tumor cells in the body. Certain substances are linked to specific types of cancer when found in increased levels in the blood. These are called tumor markers.
                         Most childhood brain tumors are diagnosed and removed in surgery. If doctors think there might be a brain tumor, a biopsy may be done to remove a sample of tissue. For tumors in the brain, the biopsy is done by removing part of the skull and using a needle to remove a sample of tissue. A pathologist views the tissue under a microscope to look for cancer cells. If cancer cells are found, the doctor may remove as much tumor as safely possible during the same surgery. The pathologist checks the cancer cells to find out the type and grade of brain tumor. The grade of the tumor is based on how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread.    The following test may be done on the sample of tissue that is removed:         -   Immunohistochemistry : A test that uses antibodies to check for certain antigens in a sample of tissue. The antibody is usually linked to a radioactive substance or a dye that causes the tissue to light up under a microscope. This type of test may be used to tell the difference between different types of cancer.         
                    					Some childhood brain and spinal cord tumors are diagnosed by imaging tests. Sometimes a biopsy or surgery cannot be done safely because of where the tumor formed in the brain or spinal cord. These tumors are diagnosed based on the results of imaging tests and other procedures.
What is the outlook for Childhood Brain and Spinal Cord Tumors ? 

Certain factors affect prognosis (chance of recovery). The prognosis (chance of recovery) depends on the following:         - Whether there are any cancer cells left after surgery.    - The type of tumor.    - Where the tumor is in the body.    - The child's age.    - Whether the tumor has just been diagnosed or has recurred (come back).
what research (or clinical trials) is being done for Childhood Brain and Spinal Cord Tumors ? 

New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     High-dose chemotherapy with stem cell transplant     High-dose chemotherapy with stem cell transplant is a way of giving high doses of chemotherapy and replacing blood -forming cells destroyed by the cancer treatment. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After the chemotherapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the bodys blood cells.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.    Clinical trials are taking place in many parts of the country. Information about clinical trials is available from the NCI website.
What is (are) Endometrial Cancer ? 

Key Points
                    - Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium.     - In the United States, endometrial cancer is the most common invasive cancer of the female reproductive system.    -  Health history and certain medicines can affect the risk of developing endometrial cancer.
                
                
                    Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium.
                    The endometrium is the innermost lining of the uterus. The uterus is a hollow, muscular organ in a woman's pelvis. The uterus is where a fetus grows. In most nonpregnant women, the uterus is about 3 inches long.     Cancer of the endometrium is different from cancer of the muscle of the uterus, which is called uterine sarcoma. See the PDQ summary on Uterine Sarcoma Treatment for more information.   See the following PDQ summaries for more information about endometrial cancer:         -  Endometrial Cancer Treatment     -  Endometrial Cancer Prevention
                
                
                    In the United States, endometrial cancer is the most common invasive cancer of the female reproductive system.
                    Endometrial cancer is diagnosed most often in postmenopausal women at an average age of 60 years.   From 2004 to 2013, the number of new cases of endometrial cancer increased slightly in white and black women. From 2005 to 2014, the number of deaths from endometrial cancer increased slightly in white and black women. When endometrial cancer is diagnosed in black women, it is usually more advanced and less likely to be cured.
Who is at risk for Endometrial Cancer? ? 

Health history and certain medicines can affect the risk of developing endometrial cancer. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. People who think they may be at risk should discuss this with their doctor. Risk factors for endometrial cancer include the following:         - Taking tamoxifen for treatment or prevention of breast cancer.    - Taking estrogen alone. (Taking estrogen in combination with progestin does not appear to increase the risk of endometrial cancer.)    - Being overweight.    - Eating a high-fat diet.    -  Never giving birth.    - Beginning menstruation at an early age.    - Reaching menopause at an older age.    - Having the gene for hereditary non-polyposis colon cancer (HNPCC).     - Being white.
Who is at risk for Wilms Tumor and Other Childhood Kidney Tumors? ? 

Having certain genetic syndromes or other conditions can increase the risk of Wilms tumor.
                    Anything that increases the risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk to your child's doctor if you think your child may be at risk.    Wilms tumor may be part of a genetic syndrome that affects growth or development. A genetic syndrome is a set of signs and symptoms or conditions that occur together and is caused by certain changes in the genes. Certain conditions can also increase a child's risk of developing Wilms tumor. These and other genetic syndromes and conditions have been linked to Wilms tumor:         -  WAGR syndrome (Wilms tumor, aniridia, abnormal genitourinary system, and mental retardation).     -  Denys-Drash syndrome (abnormal genitourinary system).    - Frasier syndrome (abnormal genitourinary system).    -  Beckwith-Wiedemann syndrome (abnormally large growth of one side of the body or a body part, large tongue, umbilical hernia at birth, and abnormal genitourinary system).     - A family history of Wilms tumor.    - Aniridia (the iris, the colored part of the eye, is missing).    - Isolated hemihyperplasia (abnormally large growth of one side of the body or a body part).    -  Urinary tract problems such as cryptorchidism or hypospadias.
                
                
                    Having certain conditions may increase the risk of renal cell cancer.
                    Renal cell cancer may be related to the following conditions:         -  Von Hippel-Lindau disease (an inherited condition that causes abnormal growth of blood vessels). Children with Von Hippel-Lindau disease should be checked yearly for renal cell cancer with an ultrasound of the abdomen or an MRI (magnetic resonance imaging) beginning at age 8 to 11 years.     -  Tuberous sclerosis (an inherited disease marked by noncancerous fatty cysts in the kidney).    -  Familial renal cell cancer (an inherited condition that occurs when certain changes in the genes that cause kidney cancer are passed down from the parent to the child).    - Renal medullary cancer (a rare kidney cancer that grows and spreads quickly).    -  Hereditary leiomyomatosis (an inherited disorder that increases the risk of having cancer of the kidney, skin, and uterus).        Prior chemotherapy or radiation therapy for a childhood cancer, such as neuroblastoma, soft tissue sarcoma, leukemia, or Wilms tumor may also increase the risk of renal cell cancer. See the Second Cancers section in the PDQ summary about Late Effects of Treatment for Childhood Cancer for more information.
What are the symptoms of Wilms Tumor and Other Childhood Kidney Tumors ? 

Signs of Wilms tumor and other childhood kidney tumors include a lump in the abdomen and blood in the urine. Sometimes childhood kidney tumors do not cause signs and symptoms and the parent finds a mass in the abdomen by chance or the mass is found during a well-child health check up. These and other signs and symptoms may be caused by kidney tumors or by other conditions. Check with your child's doctor if your child has any of the following:         - A lump, swelling, or pain in the abdomen.    - Blood in the urine.     -  High blood pressure (headache, feeling very tired, chest pain, or trouble seeing or breathing).    -  Hypercalcemia (loss of appetite, nausea and vomiting, weakness, or feeling very tired).    -  Fever for no known reason.    - Loss of appetite.    - Weight loss for no known reason.        Wilms tumor that has spread to the lungs or liver may cause the following signs and symptoms:         - Cough.    - Blood in the sputum.    - Trouble breathing.    - Pain in the abdomen.
What is the outlook for Wilms Tumor and Other Childhood Kidney Tumors ? 

Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for Wilms tumor depend on the following:         - How different the tumor cells are from normal kidney cells when looked at under a microscope.    - The stage of the cancer.    - The type of tumor.    - The age of the child.    - Whether the tumor can be completely removed by surgery.    - Whether there are certain changes in chromosomes or genes.    - Whether the cancer has just been diagnosed or has recurred (come back).        The prognosis for renal cell cancer depends on the following:         - The stage of the cancer.    - Whether the cancer has spread to the lymph nodes.        The prognosis for rhabdoid tumor of the kidney depends on the following:         - The age of the child at the time of diagnosis.    - The stage of the cancer.    - Whether the cancer has spread to the brain or spinal cord.        The prognosis for clear cell sarcoma of the kidney depends on the following:         - The age of the child at the time of diagnosis.    - The stage of the cancer.
what research (or clinical trials) is being done for Wilms Tumor and Other Childhood Kidney Tumors ? 

New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.     Targeted therapy     Targeted therapy is a treatment that uses drugs or other substances to identify and attack specific cancer cells without harming normal cells. Targeted therapy used to treat childhood kidney tumors may include the following:            -  Monoclonal antibodies: This targeted therapy uses antibodies made in the laboratory, from a single type of immune system cell. These antibodies can identify substances on cancer cells or normal substances that may help cancer cells grow. The antibodies attach to the substances and kill the cancer cells, block their growth, or keep them from spreading. Monoclonal antibodies are given by infusion. They may be used alone or to carry drugs, toxins, or radioactive material directly to cancer cells. Lorvotuzumab is being studied in the treatment of recurrent Wilms tumor.     -  Kinase inhibitors: This targeted therapy blocks signals that cancer cells need to grow and divide. LOXO-101 and entrectinib are kinase inhibitors being studied to treat congenital mesoblastic nephroma.     -  Histone methyltransferase inhibitors: This targeted therapy slows down the cancer cell's ability to grow and divide. Tazemetostat is being studied in the treatment of rhabdoid tumor of the kidney.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.