Druvith/medqa huggingface dataset:
what research (or clinical trials) is being done for Neuroblastoma ? 

New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Immunotherapy     Immunotherapy is a treatment that uses the patients immune system to fight cancer. Substances made by the body or made in a laboratory are used to boost, direct, or restore the bodys natural defenses against cancer. This type of cancer treatment is also called biotherapy or biological therapy.     Vaccine therapy uses a substance to stimulate the immune system to destroy a tumor. Vaccine therapy is being studied to treat neuroblastoma that has come back after treatment.       Other drug therapy     Lenalidomide is a type of angiogenesis inhibitor. It prevents the growth of new blood vessels that are needed by a tumor to grow.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
What causes Childhood Extracranial Germ Cell Tumors ? 

The cause of most childhood extracranial germ cell tumors is unknown.
Who is at risk for Childhood Extracranial Germ Cell Tumors? ? 

Having certain inherited disorders can increase the risk of an extracranial germ cell tumor. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your childs doctor if you think your child may be at risk.    Possible risk factors for extracranial germ cell tumors include the following:         - Having certain genetic syndromes:               -  Klinefelter syndrome may increase the risk of germ cell tumors in the mediastinum.      - Swyer syndrome may increase the risk of germ cell tumors in the testicles or ovaries.      - Turner syndrome may increase the risk of germ cell tumors in the ovaries.             - Having an undescended testicle may increase the risk of developing a testicular germ cell tumor.
What are the symptoms of Childhood Extracranial Germ Cell Tumors ? 

Signs of childhood extracranial germ cell tumors depend on the type of tumor and where it is in the body. Different tumors may cause the following signs and symptoms. Other conditions may cause these same signs and symptoms. Check with a doctor if your child has any of the following:         - A lump in the abdomen or lower back.    -  A painless lump in the testicle.    - Pain in the abdomen.    -  Fever.    -  Constipation.    - In females, no menstrual periods.    - In females, unusual vaginal bleeding.
What is the outlook for Childhood Extracranial Germ Cell Tumors ? 

Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The type of germ cell tumor.    - Where the tumor first began to grow.    - The stage of the cancer (whether it has spread to nearby areas or to other places in the body).    - How well the tumor responds to treatment (lower AFP and -hCG levels).    - Whether the tumor can be completely removed by surgery.    - The patient's age and general health.    - Whether the cancer has just been diagnosed or has recurred (come back).        The prognosis for childhood extracranial germ cell tumors, especially ovarian germ cell tumors, is good.
What is (are) Small Cell Lung Cancer ? 

Key Points
                    - Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.    - There are two main types of small cell lung cancer.     - Smoking is the major risk factor for small cell lung cancer.    - Signs and symptoms of small cell lung cancer include coughing, shortness of breath, and chest pain.    - Tests and procedures that examine the lungs are used to detect (find), diagnose, and stage small cell lung cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.    - For most patients with small cell lung cancer, current treatments do not cure the cancer.
                
                
                    Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.
                    The lungs are a pair of cone-shaped breathing organs that are found in the chest. The lungs bring oxygen into the body when you breathe in and take out carbon dioxide when you breathe out. Each lung has sections called lobes. The left lung has two lobes. The right lung, which is slightly larger, has three. A thin membrane called the pleura surrounds the lungs. Two tubes called bronchi lead from the trachea (windpipe) to the right and left lungs. The bronchi are sometimes also affected by lung cancer. Small tubes called bronchioles and tiny air sacs called alveoli make up the inside of the lungs.     There are two types of lung cancer: small cell lung cancer and non-small cell lung cancer.    This summary is about small cell lung cancer and its treatment. See the following PDQ summaries for more information about lung cancer:          -  Non-Small Cell Lung Cancer Treatment     -  Unusual Cancers of Childhood Treatment     -  Lung Cancer Prevention     -  Lung Cancer Screening
                
                
                    There are two main types of small cell lung cancer.
                    These two types include many different types of cells. The cancer cells of each type grow and spread in different ways. The types of small cell lung cancer are named for the kinds of cells found in the cancer and how the cells look when viewed under a microscope:         - Small cell carcinoma (oat cell cancer).     - Combined small cell carcinoma.
                
                
                    For most patients with small cell lung cancer, current treatments do not cure the cancer.
                    If lung cancer is found, patients should think about taking part in one of the many clinical trials being done to improve treatment. Clinical trials are taking place in most parts of the country for patients with all stages of small cell lung cancer. Information about ongoing clinical trials is available from the NCI website.
Who is at risk for Small Cell Lung Cancer? ? 

Smoking is the major risk factor for small cell lung cancer. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk to your doctor if you think you may be at risk for lung cancer.    Risk factors for lung cancer include the following:            -  Smoking cigarettes, pipes, or cigars, now or in the past. This is the most important risk factor for lung cancer. The earlier in life a person starts smoking, the more often a person smokes, and the more years a person smokes, the greater the risk of lung cancer.      -  Being exposed to secondhand smoke.     - Being exposed to radiation from any of the following:                  -  Radiation therapy to the breast or chest.       -  Radon in the home or workplace.       -  Imaging tests such as CT scans.       - Atomic bomb radiation.                 -  Being exposed to asbestos, chromium, nickel, beryllium, arsenic, soot, or tar in the workplace.     -  Living where there is air pollution.     -  Having a family history of lung cancer.     -  Being infected with the human immunodeficiency virus (HIV).     -  Taking beta carotene supplements and being a heavy smoker.           Older age is the main risk factor for most cancers. The chance of getting cancer increases as you get older.     When smoking is combined with other risk factors, the risk of lung cancer is increased.
What are the symptoms of Small Cell Lung Cancer ? 

Signs and symptoms of small cell lung cancer include coughing, shortness of breath, and chest pain. These and other signs and symptoms may be caused by small cell lung cancer or by other conditions. Check with your doctor if you have any of the following:         - Chest discomfort or pain.    - A cough that doesnt go away or gets worse over time.     - Trouble breathing.    - Wheezing.    -  Blood in sputum (mucus coughed up from the lungs).     - Hoarseness.    - Trouble swallowing.    - Loss of appetite.    - Weight loss for no known reason.    - Feeling very tired.     - Swelling in the face and/or veins in the neck.
what research (or clinical trials) is being done for Small Cell Lung Cancer ? 

New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
What is (are) Retinoblastoma ? 

Key Points
                    - Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina.    - Retinoblastoma occurs in heritable and nonheritable forms.     -  Treatment for both forms of retinoblastoma should include genetic counseling.    - Children with a family history of retinoblastoma should have eye exams to check for retinoblastoma.     - A child who has heritable retinoblastoma has an increased risk of trilateral retinoblastoma and other cancers.    - Signs and symptoms of retinoblastoma include "white pupil" and eye pain or redness.     - Tests that examine the retina are used to detect (find) and diagnose retinoblastoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina.
                    The retina is the nerve tissue that lines the inside of the back of the eye. The retina senses light and sends images to the brain by way of the optic nerve.      Although retinoblastoma may occur at any age, it occurs most often in children younger than 2 years. The cancer may be in one eye (unilateral) or in both eyes (bilateral). Retinoblastoma rarely spreads from the eye to nearby tissue or other parts of the body.    Cavitary retinoblastoma is a rare type of retinoblastoma in which cavities (hollow spaces) form within the tumor.
                
                
                    Treatment for both forms of retinoblastoma should include genetic counseling.
                    Parents should receive genetic counseling (a discussion with a trained professional about the risk of genetic diseases) to discuss genetic testing to check for a mutation (change) in the RB1 gene. Genetic counseling also includes a discussion of the risk of retinoblastoma for the child and the child's brothers or sisters.
Is Retinoblastoma inherited ? 

Retinoblastoma occurs in heritable and nonheritable forms.
                    A child is thought to have the heritable form of retinoblastoma when one of the following is true:         - There is a family history of retinoblastoma.    - There is a certain mutation (change) in the RB1 gene. The mutation in the RB1 gene may be passed from the parent to the child or it may occur in the egg or sperm before conception or soon after conception.    - There is more than one tumor in the eye or there is a tumor in both eyes.    - There is a tumor in one eye and the child is younger than 1 year.        After heritable retinoblastoma has been diagnosed and treated, new tumors may continue to form for a few years. Regular eye exams to check for new tumors are usually done every 2 to 4 months for at least 28 months.    Nonheritable retinoblastoma is retinoblastoma that is not the heritable form. Most cases of retinoblastoma are the nonheritable form.
                
                
                    Treatment for both forms of retinoblastoma should include genetic counseling.
                    Parents should receive genetic counseling (a discussion with a trained professional about the risk of genetic diseases) to discuss genetic testing to check for a mutation (change) in the RB1 gene. Genetic counseling also includes a discussion of the risk of retinoblastoma for the child and the child's brothers or sisters.
                
                
                    Children with a family history of retinoblastoma should have eye exams to check for retinoblastoma.
                    A child with a family history of retinoblastoma should have regular eye exams beginning early in life to check for retinoblastoma, unless it is known that the child does not have the RB1 gene change. Early diagnosis of retinoblastoma may mean the child will need less intense treatment.   Brothers or sisters of a child with retinoblastoma should have regular eye exams by an ophthalmologist until age 3 to 5 years, unless it is known that the brother or sister does not have the RB1 gene change.
                
                
                    A child who has heritable retinoblastoma has an increased risk of trilateral retinoblastoma and other cancers.
                    A child with heritable retinoblastoma has an increased risk of a pineal tumor in the brain. When retinoblastoma and a brain tumor occur at the same time, it is called trilateral retinoblastoma. The brain tumor is usually diagnosed between 20 and 36 months of age. Regular screening using MRI (magnetic resonance imaging) may be done for a child thought to have heritable retinoblastoma or for a child with retinoblastoma in one eye and a family history of the disease. CT (computerized tomography) scans are usually not used for routine screening in order to avoid exposing the child to ionizing radiation.    Heritable retinoblastoma also increases the child's risk of other types of cancer such as lung cancer, bladder cancer, or melanoma in later years. Regular follow-up exams are important.
Who is at risk for Retinoblastoma? ? 

A child who has heritable retinoblastoma has an increased risk of trilateral retinoblastoma and other cancers. A child with heritable retinoblastoma has an increased risk of a pineal tumor in the brain. When retinoblastoma and a brain tumor occur at the same time, it is called trilateral retinoblastoma. The brain tumor is usually diagnosed between 20 and 36 months of age. Regular screening using MRI (magnetic resonance imaging) may be done for a child thought to have heritable retinoblastoma or for a child with retinoblastoma in one eye and a family history of the disease. CT (computerized tomography) scans are usually not used for routine screening in order to avoid exposing the child to ionizing radiation.    Heritable retinoblastoma also increases the child's risk of other types of cancer such as lung cancer, bladder cancer, or melanoma in later years. Regular follow-up exams are important.
What are the symptoms of Retinoblastoma ? 

These and other signs and symptoms may be caused by retinoblastoma or by other conditions. Check with a doctor if your child has any of the following:         -  Pupil of the eye appears white instead of red when light shines into it. This may be seen in flash photographs of the child.    - Eyes appear to be looking in different directions (lazy eye).    - Pain or redness in the eye.    -  Infection around the eye.     - Eyeball is larger than normal.     - Colored part of the eye and pupil look cloudy.
How to diagnose Retinoblastoma ? 

The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken. The doctor will ask if there is a family history of retinoblastoma.    -  Eye exam with dilated pupil: An exam of the eye in which the pupil is dilated (opened wider) with medicated eye drops to allow the doctor to look through the lens and pupil to the retina. The inside of the eye, including the retina and the optic nerve, is examined with a light. Depending on the age of the child, this exam may be done under anesthesia. There are several types of eye exams that are done with the pupil dilated:               -  Ophthalmoscopy : An exam of the inside of the back of the eye to check the retina and optic nerve using a small magnifying lens and a light.      -  Slit-lamp biomicroscopy : An exam of the inside of the eye to check the retina, optic nerve, and other parts of the eye using a strong beam of light and a microscope.      - Fluorescein angiography : A procedure to look at blood vessels and the flow of blood inside the eye. An orange fluorescent dye called fluorescein is injected into a blood vessel in the arm and goes into the bloodstream. As the dye travels through blood vessels of the eye, a special camera takes pictures of the retina and choroid to find any blood vessels that are blocked or leaking.              -   RB1 gene test: A laboratory test in which a sample of blood or tissue is tested for a change in the RB1 gene.    -   Ultrasound exam of the eye: A procedure in which high-energy sound waves (ultrasound) are bounced off the internal tissues of the eye to make echoes. Eye drops are used to numb the eye and a small probe that sends and receives sound waves is placed gently on the surface of the eye. The echoes make a picture of the inside of the eye and the distance from the cornea to the retina is measured. The picture, called a sonogram, shows on the screen of the ultrasound monitor. The picture can be printed to be looked at later.    -  MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body, such as the eye. This procedure is also called nuclear magnetic resonance imaging (NMRI).    -  CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, such as the eye, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.        Retinoblastoma can usually be diagnosed without a biopsy.   When retinoblastoma is in one eye, it sometimes forms in the other eye. Exams of the unaffected eye are done until it is known if the retinoblastoma is the heritable form.
What is the outlook for Retinoblastoma ? 

The prognosis (chance of recovery) and treatment options depend on the following:         - Whether the cancer is in one or both eyes.    - The size and number of tumors.    - Whether the tumor has spread to the area around the eye, to the brain, or to other parts of the body.    - Whether there are symptoms at the time of diagnosis, for trilateral retinoblastoma.    - The age of the child.    - How likely it is that vision can be saved in one or both eyes.    - Whether a second type of cancer has formed.
what research (or clinical trials) is being done for Retinoblastoma ? 

New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.